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Search of human proteins with 155030192
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|155030192 RAP1, GTP-GDP dissociation stimulator 1 isoform 1
[Homo sapiens]
(608 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|155030192 RAP1, GTP-GDP dissociation stimulator 1 isoform 1 [... 1164 0.0
gi|155030196 RAP1, GTP-GDP dissociation stimulator 1 isoform 3 [... 1160 0.0
gi|155030194 RAP1, GTP-GDP dissociation stimulator 1 isoform 2 [... 1157 0.0
gi|155030198 RAP1, GTP-GDP dissociation stimulator 1 isoform 4 [... 1036 0.0
gi|155030200 RAP1, GTP-GDP dissociation stimulator 1 isoform 5 [... 1033 0.0
gi|155030202 RAP1, GTP-GDP dissociation stimulator 1 isoform 6 [... 759 0.0
gi|189409124 armadillo repeat containing 3 [Homo sapiens] 54 3e-07
gi|224589129 karyopherin 7 [Homo sapiens] 48 2e-05
gi|31657114 armadillo repeat containing 4 [Homo sapiens] 47 4e-05
gi|39812229 karyopherin alpha 5 [Homo sapiens] 46 9e-05
gi|4504897 karyopherin alpha 2 [Homo sapiens] 44 4e-04
gi|11034811 catenin (cadherin-associated protein), delta 2 (neur... 40 0.006
gi|94536840 transmembrane and coiled-coil domains 6 [Homo sapiens] 39 0.011
gi|91206450 ankyrin and armadillo repeat containing [Homo sapiens] 38 0.024
gi|4504811 junction plakoglobin [Homo sapiens] 38 0.031
gi|12056468 junction plakoglobin [Homo sapiens] 38 0.031
gi|6912678 sperm associated antigen 6 isoform 1 [Homo sapiens] 38 0.031
gi|27262641 sperm associated antigen 6 isoform 2 [Homo sapiens] 38 0.031
gi|148227672 catenin (cadherin-associated protein), beta 1, 88kD... 37 0.053
gi|148233338 catenin (cadherin-associated protein), beta 1, 88kD... 37 0.053
gi|4503131 catenin (cadherin-associated protein), beta 1, 88kDa ... 37 0.053
gi|15529984 armadillo repeat containing 6 [Homo sapiens] 37 0.069
gi|7106299 ataxin 10 [Homo sapiens] 36 0.12
gi|4504901 karyopherin alpha 4 [Homo sapiens] 35 0.15
gi|222144293 karyopherin alpha 1 [Homo sapiens] 34 0.45
gi|146231975 catenin, delta 1 isoform 3A [Homo sapiens] 34 0.45
gi|146231948 catenin, delta 1 isoform 3A [Homo sapiens] 34 0.45
gi|146231994 catenin, delta 1 isoform 3A [Homo sapiens] 34 0.45
gi|146231977 catenin, delta 1 isoform 3AC [Homo sapiens] 34 0.45
gi|146231946 catenin, delta 1 isoform 3B [Homo sapiens] 34 0.45
>gi|155030192 RAP1, GTP-GDP dissociation stimulator 1 isoform 1
[Homo sapiens]
Length = 608
Score = 1164 bits (3010), Expect = 0.0
Identities = 608/608 (100%), Positives = 608/608 (100%)
Query: 1 MADNLSDTLKKLKITAVDKTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFASLLT 60
MADNLSDTLKKLKITAVDKTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFASLLT
Sbjct: 1 MADNLSDTLKKLKITAVDKTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFASLLT 60
Query: 61 PQSSCKAKVANIIAEVAKNEFMRIPCVDAGLISPLVQLLNSKDQEVLLQTGRALGNICYD 120
PQSSCKAKVANIIAEVAKNEFMRIPCVDAGLISPLVQLLNSKDQEVLLQTGRALGNICYD
Sbjct: 61 PQSSCKAKVANIIAEVAKNEFMRIPCVDAGLISPLVQLLNSKDQEVLLQTGRALGNICYD 120
Query: 121 SHEGRSAVDQAGGAQIVIDHLRSLCSITDPANEKLLTVFCGMLMNYSNENDSLQAQLINM 180
SHEGRSAVDQAGGAQIVIDHLRSLCSITDPANEKLLTVFCGMLMNYSNENDSLQAQLINM
Sbjct: 121 SHEGRSAVDQAGGAQIVIDHLRSLCSITDPANEKLLTVFCGMLMNYSNENDSLQAQLINM 180
Query: 181 GVIPTLVKLLGIHCQNAALTEMCLVAFGNLAELESSKEQFASTNIAEELVKLFKKQIEHD 240
GVIPTLVKLLGIHCQNAALTEMCLVAFGNLAELESSKEQFASTNIAEELVKLFKKQIEHD
Sbjct: 181 GVIPTLVKLLGIHCQNAALTEMCLVAFGNLAELESSKEQFASTNIAEELVKLFKKQIEHD 240
Query: 241 KREMIFEVLAPLAENDAIKLQLVEAGLVECLLEIVQQKVDSDKEDDITELKTGSDLMVLL 300
KREMIFEVLAPLAENDAIKLQLVEAGLVECLLEIVQQKVDSDKEDDITELKTGSDLMVLL
Sbjct: 241 KREMIFEVLAPLAENDAIKLQLVEAGLVECLLEIVQQKVDSDKEDDITELKTGSDLMVLL 300
Query: 301 LLGDESMQKLFEGGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARNDANCIHMVDNGIV 360
LLGDESMQKLFEGGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARNDANCIHMVDNGIV
Sbjct: 301 LLGDESMQKLFEGGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARNDANCIHMVDNGIV 360
Query: 361 EKLMDLLDRHVEDGNVTVQHAALSALRNLAIPVINKAKMLSAGVTEAVLKFLKSEMPPVQ 420
EKLMDLLDRHVEDGNVTVQHAALSALRNLAIPVINKAKMLSAGVTEAVLKFLKSEMPPVQ
Sbjct: 361 EKLMDLLDRHVEDGNVTVQHAALSALRNLAIPVINKAKMLSAGVTEAVLKFLKSEMPPVQ 420
Query: 421 FKLLGTLRMLIDAQAEAAEQLGKNVKLVERLVEWCEAKDHAGVMGESNRLLSALIRHSKS 480
FKLLGTLRMLIDAQAEAAEQLGKNVKLVERLVEWCEAKDHAGVMGESNRLLSALIRHSKS
Sbjct: 421 FKLLGTLRMLIDAQAEAAEQLGKNVKLVERLVEWCEAKDHAGVMGESNRLLSALIRHSKS 480
Query: 481 KDVIKTIVQSGGIKHLVTMATSEHVIMQNEALVALALIAALELGTAEKDLESAKLVQILH 540
KDVIKTIVQSGGIKHLVTMATSEHVIMQNEALVALALIAALELGTAEKDLESAKLVQILH
Sbjct: 481 KDVIKTIVQSGGIKHLVTMATSEHVIMQNEALVALALIAALELGTAEKDLESAKLVQILH 540
Query: 541 RLLADERSAPEIKYNSMVLICALMGSECLHKEVQDLAFLDVVSKLRSHENKSVAQQASLT 600
RLLADERSAPEIKYNSMVLICALMGSECLHKEVQDLAFLDVVSKLRSHENKSVAQQASLT
Sbjct: 541 RLLADERSAPEIKYNSMVLICALMGSECLHKEVQDLAFLDVVSKLRSHENKSVAQQASLT 600
Query: 601 EQRLTVES 608
EQRLTVES
Sbjct: 601 EQRLTVES 608
>gi|155030196 RAP1, GTP-GDP dissociation stimulator 1 isoform 3
[Homo sapiens]
Length = 607
Score = 1160 bits (3001), Expect = 0.0
Identities = 606/606 (100%), Positives = 606/606 (100%)
Query: 3 DNLSDTLKKLKITAVDKTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFASLLTPQ 62
DNLSDTLKKLKITAVDKTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFASLLTPQ
Sbjct: 2 DNLSDTLKKLKITAVDKTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFASLLTPQ 61
Query: 63 SSCKAKVANIIAEVAKNEFMRIPCVDAGLISPLVQLLNSKDQEVLLQTGRALGNICYDSH 122
SSCKAKVANIIAEVAKNEFMRIPCVDAGLISPLVQLLNSKDQEVLLQTGRALGNICYDSH
Sbjct: 62 SSCKAKVANIIAEVAKNEFMRIPCVDAGLISPLVQLLNSKDQEVLLQTGRALGNICYDSH 121
Query: 123 EGRSAVDQAGGAQIVIDHLRSLCSITDPANEKLLTVFCGMLMNYSNENDSLQAQLINMGV 182
EGRSAVDQAGGAQIVIDHLRSLCSITDPANEKLLTVFCGMLMNYSNENDSLQAQLINMGV
Sbjct: 122 EGRSAVDQAGGAQIVIDHLRSLCSITDPANEKLLTVFCGMLMNYSNENDSLQAQLINMGV 181
Query: 183 IPTLVKLLGIHCQNAALTEMCLVAFGNLAELESSKEQFASTNIAEELVKLFKKQIEHDKR 242
IPTLVKLLGIHCQNAALTEMCLVAFGNLAELESSKEQFASTNIAEELVKLFKKQIEHDKR
Sbjct: 182 IPTLVKLLGIHCQNAALTEMCLVAFGNLAELESSKEQFASTNIAEELVKLFKKQIEHDKR 241
Query: 243 EMIFEVLAPLAENDAIKLQLVEAGLVECLLEIVQQKVDSDKEDDITELKTGSDLMVLLLL 302
EMIFEVLAPLAENDAIKLQLVEAGLVECLLEIVQQKVDSDKEDDITELKTGSDLMVLLLL
Sbjct: 242 EMIFEVLAPLAENDAIKLQLVEAGLVECLLEIVQQKVDSDKEDDITELKTGSDLMVLLLL 301
Query: 303 GDESMQKLFEGGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARNDANCIHMVDNGIVEK 362
GDESMQKLFEGGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARNDANCIHMVDNGIVEK
Sbjct: 302 GDESMQKLFEGGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARNDANCIHMVDNGIVEK 361
Query: 363 LMDLLDRHVEDGNVTVQHAALSALRNLAIPVINKAKMLSAGVTEAVLKFLKSEMPPVQFK 422
LMDLLDRHVEDGNVTVQHAALSALRNLAIPVINKAKMLSAGVTEAVLKFLKSEMPPVQFK
Sbjct: 362 LMDLLDRHVEDGNVTVQHAALSALRNLAIPVINKAKMLSAGVTEAVLKFLKSEMPPVQFK 421
Query: 423 LLGTLRMLIDAQAEAAEQLGKNVKLVERLVEWCEAKDHAGVMGESNRLLSALIRHSKSKD 482
LLGTLRMLIDAQAEAAEQLGKNVKLVERLVEWCEAKDHAGVMGESNRLLSALIRHSKSKD
Sbjct: 422 LLGTLRMLIDAQAEAAEQLGKNVKLVERLVEWCEAKDHAGVMGESNRLLSALIRHSKSKD 481
Query: 483 VIKTIVQSGGIKHLVTMATSEHVIMQNEALVALALIAALELGTAEKDLESAKLVQILHRL 542
VIKTIVQSGGIKHLVTMATSEHVIMQNEALVALALIAALELGTAEKDLESAKLVQILHRL
Sbjct: 482 VIKTIVQSGGIKHLVTMATSEHVIMQNEALVALALIAALELGTAEKDLESAKLVQILHRL 541
Query: 543 LADERSAPEIKYNSMVLICALMGSECLHKEVQDLAFLDVVSKLRSHENKSVAQQASLTEQ 602
LADERSAPEIKYNSMVLICALMGSECLHKEVQDLAFLDVVSKLRSHENKSVAQQASLTEQ
Sbjct: 542 LADERSAPEIKYNSMVLICALMGSECLHKEVQDLAFLDVVSKLRSHENKSVAQQASLTEQ 601
Query: 603 RLTVES 608
RLTVES
Sbjct: 602 RLTVES 607
>gi|155030194 RAP1, GTP-GDP dissociation stimulator 1 isoform 2
[Homo sapiens]
Length = 607
Score = 1157 bits (2994), Expect = 0.0
Identities = 607/608 (99%), Positives = 607/608 (99%), Gaps = 1/608 (0%)
Query: 1 MADNLSDTLKKLKITAVDKTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFASLLT 60
MADNLSDTLKKLKITAVDKTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFASLLT
Sbjct: 1 MADNLSDTLKKLKITAVDKTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFASLLT 60
Query: 61 PQSSCKAKVANIIAEVAKNEFMRIPCVDAGLISPLVQLLNSKDQEVLLQTGRALGNICYD 120
PQSSCKAKVANIIAEVAKNEFMRIPCVDAGLISPLVQLLNSKDQEVLLQTGRALGNICYD
Sbjct: 61 PQSSCKAKVANIIAEVAKNEFMRIPCVDAGLISPLVQLLNSKDQEVLLQTGRALGNICYD 120
Query: 121 SHEGRSAVDQAGGAQIVIDHLRSLCSITDPANEKLLTVFCGMLMNYSNENDSLQAQLINM 180
SHEGRSAVDQAGGAQIVIDHLRSLCSITDPANEKLLTVFCGMLMNYSNENDSLQAQLINM
Sbjct: 121 SHEGRSAVDQAGGAQIVIDHLRSLCSITDPANEKLLTVFCGMLMNYSNENDSLQAQLINM 180
Query: 181 GVIPTLVKLLGIHCQNAALTEMCLVAFGNLAELESSKEQFASTNIAEELVKLFKKQIEHD 240
GVIPTLVKLLGIHCQNAALTEMCLVAFGNLAELESSKEQFASTNIAEELVKLFKKQIEHD
Sbjct: 181 GVIPTLVKLLGIHCQNAALTEMCLVAFGNLAELESSKEQFASTNIAEELVKLFKKQIEHD 240
Query: 241 KREMIFEVLAPLAENDAIKLQLVEAGLVECLLEIVQQKVDSDKEDDITELKTGSDLMVLL 300
KREMIFEVLAPLAENDAIKLQLVEAGLVECLLEIVQQKVDSDKEDDITELKTGSDLMVLL
Sbjct: 241 KREMIFEVLAPLAENDAIKLQLVEAGLVECLLEIVQQKVDSDKEDDITELKTGSDLMVLL 300
Query: 301 LLGDESMQKLFEGGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARNDANCIHMVDNGIV 360
LLGDESMQKLFEGGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARNDANCIHMVDNGIV
Sbjct: 301 LLGDESMQKLFEGGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARNDANCIHMVDNGIV 360
Query: 361 EKLMDLLDRHVEDGNVTVQHAALSALRNLAIPVINKAKMLSAGVTEAVLKFLKSEMPPVQ 420
EKLMDLLDRHVEDGNVTVQHAALSALRNLAIPVINKAKMLSAGVTEAVLKFLKSEMPPVQ
Sbjct: 361 EKLMDLLDRHVEDGNVTVQHAALSALRNLAIPVINKAKMLSAGVTEAVLKFLKSEMPPVQ 420
Query: 421 FKLLGTLRMLIDAQAEAAEQLGKNVKLVERLVEWCEAKDHAGVMGESNRLLSALIRHSKS 480
FKLLGTLRMLIDAQ EAAEQLGKNVKLVERLVEWCEAKDHAGVMGESNRLLSALIRHSKS
Sbjct: 421 FKLLGTLRMLIDAQ-EAAEQLGKNVKLVERLVEWCEAKDHAGVMGESNRLLSALIRHSKS 479
Query: 481 KDVIKTIVQSGGIKHLVTMATSEHVIMQNEALVALALIAALELGTAEKDLESAKLVQILH 540
KDVIKTIVQSGGIKHLVTMATSEHVIMQNEALVALALIAALELGTAEKDLESAKLVQILH
Sbjct: 480 KDVIKTIVQSGGIKHLVTMATSEHVIMQNEALVALALIAALELGTAEKDLESAKLVQILH 539
Query: 541 RLLADERSAPEIKYNSMVLICALMGSECLHKEVQDLAFLDVVSKLRSHENKSVAQQASLT 600
RLLADERSAPEIKYNSMVLICALMGSECLHKEVQDLAFLDVVSKLRSHENKSVAQQASLT
Sbjct: 540 RLLADERSAPEIKYNSMVLICALMGSECLHKEVQDLAFLDVVSKLRSHENKSVAQQASLT 599
Query: 601 EQRLTVES 608
EQRLTVES
Sbjct: 600 EQRLTVES 607
>gi|155030198 RAP1, GTP-GDP dissociation stimulator 1 isoform 4
[Homo sapiens]
Length = 559
Score = 1036 bits (2680), Expect = 0.0
Identities = 556/608 (91%), Positives = 558/608 (91%), Gaps = 49/608 (8%)
Query: 1 MADNLSDTLKKLKITAVDKTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFASLLT 60
MADNLSDTLKKLKITAVDKTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFASLLT
Sbjct: 1 MADNLSDTLKKLKITAVDKTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFASLLT 60
Query: 61 PQSSCKAKVANIIAEVAKNEFMRIPCVDAGLISPLVQLLNSKDQEVLLQTGRALGNICYD 120
PQSSCKAKVANIIAEVAKNEFMRIPCVDAGLISPLVQLLNSKDQEVLLQTGRALGNICY
Sbjct: 61 PQSSCKAKVANIIAEVAKNEFMRIPCVDAGLISPLVQLLNSKDQEVLLQTGRALGNICY- 119
Query: 121 SHEGRSAVDQAGGAQIVIDHLRSLCSITDPANEKLLTVFCGMLMNYSNENDSLQAQLINM 180
++ SLQAQLINM
Sbjct: 120 ------------------------------------------------DSHSLQAQLINM 131
Query: 181 GVIPTLVKLLGIHCQNAALTEMCLVAFGNLAELESSKEQFASTNIAEELVKLFKKQIEHD 240
GVIPTLVKLLGIHCQNAALTEMCLVAFGNLAELESSKEQFASTNIAEELVKLFKKQIEHD
Sbjct: 132 GVIPTLVKLLGIHCQNAALTEMCLVAFGNLAELESSKEQFASTNIAEELVKLFKKQIEHD 191
Query: 241 KREMIFEVLAPLAENDAIKLQLVEAGLVECLLEIVQQKVDSDKEDDITELKTGSDLMVLL 300
KREMIFEVLAPLAENDAIKLQLVEAGLVECLLEIVQQKVDSDKEDDITELKTGSDLMVLL
Sbjct: 192 KREMIFEVLAPLAENDAIKLQLVEAGLVECLLEIVQQKVDSDKEDDITELKTGSDLMVLL 251
Query: 301 LLGDESMQKLFEGGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARNDANCIHMVDNGIV 360
LLGDESMQKLFEGGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARNDANCIHMVDNGIV
Sbjct: 252 LLGDESMQKLFEGGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARNDANCIHMVDNGIV 311
Query: 361 EKLMDLLDRHVEDGNVTVQHAALSALRNLAIPVINKAKMLSAGVTEAVLKFLKSEMPPVQ 420
EKLMDLLDRHVEDGNVTVQHAALSALRNLAIPVINKAKMLSAGVTEAVLKFLKSEMPPVQ
Sbjct: 312 EKLMDLLDRHVEDGNVTVQHAALSALRNLAIPVINKAKMLSAGVTEAVLKFLKSEMPPVQ 371
Query: 421 FKLLGTLRMLIDAQAEAAEQLGKNVKLVERLVEWCEAKDHAGVMGESNRLLSALIRHSKS 480
FKLLGTLRMLIDAQAEAAEQLGKNVKLVERLVEWCEAKDHAGVMGESNRLLSALIRHSKS
Sbjct: 372 FKLLGTLRMLIDAQAEAAEQLGKNVKLVERLVEWCEAKDHAGVMGESNRLLSALIRHSKS 431
Query: 481 KDVIKTIVQSGGIKHLVTMATSEHVIMQNEALVALALIAALELGTAEKDLESAKLVQILH 540
KDVIKTIVQSGGIKHLVTMATSEHVIMQNEALVALALIAALELGTAEKDLESAKLVQILH
Sbjct: 432 KDVIKTIVQSGGIKHLVTMATSEHVIMQNEALVALALIAALELGTAEKDLESAKLVQILH 491
Query: 541 RLLADERSAPEIKYNSMVLICALMGSECLHKEVQDLAFLDVVSKLRSHENKSVAQQASLT 600
RLLADERSAPEIKYNSMVLICALMGSECLHKEVQDLAFLDVVSKLRSHENKSVAQQASLT
Sbjct: 492 RLLADERSAPEIKYNSMVLICALMGSECLHKEVQDLAFLDVVSKLRSHENKSVAQQASLT 551
Query: 601 EQRLTVES 608
EQRLTVES
Sbjct: 552 EQRLTVES 559
>gi|155030200 RAP1, GTP-GDP dissociation stimulator 1 isoform 5
[Homo sapiens]
Length = 558
Score = 1033 bits (2671), Expect = 0.0
Identities = 554/606 (91%), Positives = 556/606 (91%), Gaps = 49/606 (8%)
Query: 3 DNLSDTLKKLKITAVDKTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFASLLTPQ 62
DNLSDTLKKLKITAVDKTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFASLLTPQ
Sbjct: 2 DNLSDTLKKLKITAVDKTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFASLLTPQ 61
Query: 63 SSCKAKVANIIAEVAKNEFMRIPCVDAGLISPLVQLLNSKDQEVLLQTGRALGNICYDSH 122
SSCKAKVANIIAEVAKNEFMRIPCVDAGLISPLVQLLNSKDQEVLLQTGRALGNICY
Sbjct: 62 SSCKAKVANIIAEVAKNEFMRIPCVDAGLISPLVQLLNSKDQEVLLQTGRALGNICY--- 118
Query: 123 EGRSAVDQAGGAQIVIDHLRSLCSITDPANEKLLTVFCGMLMNYSNENDSLQAQLINMGV 182
++ SLQAQLINMGV
Sbjct: 119 ----------------------------------------------DSHSLQAQLINMGV 132
Query: 183 IPTLVKLLGIHCQNAALTEMCLVAFGNLAELESSKEQFASTNIAEELVKLFKKQIEHDKR 242
IPTLVKLLGIHCQNAALTEMCLVAFGNLAELESSKEQFASTNIAEELVKLFKKQIEHDKR
Sbjct: 133 IPTLVKLLGIHCQNAALTEMCLVAFGNLAELESSKEQFASTNIAEELVKLFKKQIEHDKR 192
Query: 243 EMIFEVLAPLAENDAIKLQLVEAGLVECLLEIVQQKVDSDKEDDITELKTGSDLMVLLLL 302
EMIFEVLAPLAENDAIKLQLVEAGLVECLLEIVQQKVDSDKEDDITELKTGSDLMVLLLL
Sbjct: 193 EMIFEVLAPLAENDAIKLQLVEAGLVECLLEIVQQKVDSDKEDDITELKTGSDLMVLLLL 252
Query: 303 GDESMQKLFEGGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARNDANCIHMVDNGIVEK 362
GDESMQKLFEGGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARNDANCIHMVDNGIVEK
Sbjct: 253 GDESMQKLFEGGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARNDANCIHMVDNGIVEK 312
Query: 363 LMDLLDRHVEDGNVTVQHAALSALRNLAIPVINKAKMLSAGVTEAVLKFLKSEMPPVQFK 422
LMDLLDRHVEDGNVTVQHAALSALRNLAIPVINKAKMLSAGVTEAVLKFLKSEMPPVQFK
Sbjct: 313 LMDLLDRHVEDGNVTVQHAALSALRNLAIPVINKAKMLSAGVTEAVLKFLKSEMPPVQFK 372
Query: 423 LLGTLRMLIDAQAEAAEQLGKNVKLVERLVEWCEAKDHAGVMGESNRLLSALIRHSKSKD 482
LLGTLRMLIDAQAEAAEQLGKNVKLVERLVEWCEAKDHAGVMGESNRLLSALIRHSKSKD
Sbjct: 373 LLGTLRMLIDAQAEAAEQLGKNVKLVERLVEWCEAKDHAGVMGESNRLLSALIRHSKSKD 432
Query: 483 VIKTIVQSGGIKHLVTMATSEHVIMQNEALVALALIAALELGTAEKDLESAKLVQILHRL 542
VIKTIVQSGGIKHLVTMATSEHVIMQNEALVALALIAALELGTAEKDLESAKLVQILHRL
Sbjct: 433 VIKTIVQSGGIKHLVTMATSEHVIMQNEALVALALIAALELGTAEKDLESAKLVQILHRL 492
Query: 543 LADERSAPEIKYNSMVLICALMGSECLHKEVQDLAFLDVVSKLRSHENKSVAQQASLTEQ 602
LADERSAPEIKYNSMVLICALMGSECLHKEVQDLAFLDVVSKLRSHENKSVAQQASLTEQ
Sbjct: 493 LADERSAPEIKYNSMVLICALMGSECLHKEVQDLAFLDVVSKLRSHENKSVAQQASLTEQ 552
Query: 603 RLTVES 608
RLTVES
Sbjct: 553 RLTVES 558
>gi|155030202 RAP1, GTP-GDP dissociation stimulator 1 isoform 6
[Homo sapiens]
Length = 516
Score = 759 bits (1959), Expect = 0.0
Identities = 406/441 (92%), Positives = 417/441 (94%), Gaps = 3/441 (0%)
Query: 169 ENDSLQAQLINMGVIPTLVKLLGIHCQNAALTEMCLVAFGNLA-ELESSKEQFASTNIAE 227
+N+ ++ ++ G+I LV+LL Q L A GN+ + +SSKEQFASTNIAE
Sbjct: 78 KNEFMRIPCVDAGLISPLVQLLNSKDQEVLLQTGR--ALGNICYDSQSSKEQFASTNIAE 135
Query: 228 ELVKLFKKQIEHDKREMIFEVLAPLAENDAIKLQLVEAGLVECLLEIVQQKVDSDKEDDI 287
ELVKLFKKQIEHDKREMIFEVLAPLAENDAIKLQLVEAGLVECLLEIVQQKVDSDKEDDI
Sbjct: 136 ELVKLFKKQIEHDKREMIFEVLAPLAENDAIKLQLVEAGLVECLLEIVQQKVDSDKEDDI 195
Query: 288 TELKTGSDLMVLLLLGDESMQKLFEGGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARN 347
TELKTGSDLMVLLLLGDESMQKLFEGGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARN
Sbjct: 196 TELKTGSDLMVLLLLGDESMQKLFEGGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARN 255
Query: 348 DANCIHMVDNGIVEKLMDLLDRHVEDGNVTVQHAALSALRNLAIPVINKAKMLSAGVTEA 407
DANCIHMVDNGIVEKLMDLLDRHVEDGNVTVQHAALSALRNLAIPVINKAKMLSAGVTEA
Sbjct: 256 DANCIHMVDNGIVEKLMDLLDRHVEDGNVTVQHAALSALRNLAIPVINKAKMLSAGVTEA 315
Query: 408 VLKFLKSEMPPVQFKLLGTLRMLIDAQAEAAEQLGKNVKLVERLVEWCEAKDHAGVMGES 467
VLKFLKSEMPPVQFKLLGTLRMLIDAQAEAAEQLGKNVKLVERLVEWCEAKDHAGVMGES
Sbjct: 316 VLKFLKSEMPPVQFKLLGTLRMLIDAQAEAAEQLGKNVKLVERLVEWCEAKDHAGVMGES 375
Query: 468 NRLLSALIRHSKSKDVIKTIVQSGGIKHLVTMATSEHVIMQNEALVALALIAALELGTAE 527
NRLLSALIRHSKSKDVIKTIVQSGGIKHLVTMATSEHVIMQNEALVALALIAALELGTAE
Sbjct: 376 NRLLSALIRHSKSKDVIKTIVQSGGIKHLVTMATSEHVIMQNEALVALALIAALELGTAE 435
Query: 528 KDLESAKLVQILHRLLADERSAPEIKYNSMVLICALMGSECLHKEVQDLAFLDVVSKLRS 587
KDLESAKLVQILHRLLADERSAPEIKYNSMVLICALMGSECLHKEVQDLAFLDVVSKLRS
Sbjct: 436 KDLESAKLVQILHRLLADERSAPEIKYNSMVLICALMGSECLHKEVQDLAFLDVVSKLRS 495
Query: 588 HENKSVAQQASLTEQRLTVES 608
HENKSVAQQASLTEQRLTVES
Sbjct: 496 HENKSVAQQASLTEQRLTVES 516
>gi|189409124 armadillo repeat containing 3 [Homo sapiens]
Length = 872
Score = 54.3 bits (129), Expect = 3e-07
Identities = 81/355 (22%), Positives = 154/355 (43%), Gaps = 38/355 (10%)
Query: 259 KLQLVEAGLVECLLEIVQQKVDSDKEDDITELKTGSDLMVLLLLGDESMQKLFEGGKGSV 318
K L+E G VE L +++ ED I ++ + ++ +L + ++KL + V
Sbjct: 60 KTTLLELGAVEPLTKLLTH------EDKI--VRRNATMIFGILASNNDVKKLLR--ELDV 109
Query: 319 FQRVLSWI-PSNNHQLQLAGALAIANFARNDANCIHMVDNGIVEKLMDLLDRHVEDGNVT 377
V++ + P + +L +AN + + + + ++G +E L+ LL D
Sbjct: 110 MNSVIAQLAPEEEVVIHEFASLCLANMSAEYTSKVQIFEHGGLEPLIRLLSSPDPD---- 165
Query: 378 VQHAALSALRNLAIPVINKAKMLSAGVTEAVLKFLKSEMPPVQFKLLGTLRMLIDAQAEA 437
V+ ++ + NL +AK+ +L LKSE P +Q L TL ++ + E+
Sbjct: 166 VKKNSMECIYNLVQDFQCRAKLQELNAIPPILDLLKSEYPVIQLLALKTLGVIAN-DKES 224
Query: 438 AEQLGKNVKLVERLVEWCEAKDHAGVMGESNRLLSALIRHSKSKDVIKTIVQSGGIKHLV 497
L N L + L++ E K+ + E+ L+ + + D + I Q+GG+K L+
Sbjct: 225 RTMLRDNQGL-DHLIKILETKELNDLHIEA---LAVIANCLEDMDTMVQIQQTGGLKKLL 280
Query: 498 TMATSEHVIMQNEALVALALIAALELGTAEKDLESAKLV------QILHRLLADERSAPE 551
+ A +N + + AA + A D E+ KL + L LL E +
Sbjct: 281 SFA-------ENSTIPDIQKNAAKAITKAAYDPENRKLFHEQEVEKCLVALLGSENDGTK 333
Query: 552 IKYNSMV-LICALMGSECLHKEVQDLAFLDVVSKLRSHENKSVAQQASLTEQRLT 605
I + + +C GS K+ + + + +L +N+ V + A+L LT
Sbjct: 334 IAASQAISAMCENSGS----KDFFNNQGIPQLIQLLKSDNEEVREAAALALANLT 384
Score = 41.6 bits (96), Expect = 0.002
Identities = 98/535 (18%), Positives = 219/535 (40%), Gaps = 63/535 (11%)
Query: 87 VDAGLISPLVQLLNSKDQEVLLQTGRALGNICYDSHEGRSAVDQAGGAQIVIDHLRSLCS 146
+++ + +V +LNS ++E+L + A+ E ++ + + G ++ L L +
Sbjct: 22 IESKKAATVVLMLNSPEEEILAKACEAIYKFALKGEENKTTLLELG----AVEPLTKLLT 77
Query: 147 ITDPANEKLLTVFCGMLMNYSNENDSLQAQLINMGVIPTLVKLLGIHCQNAALTEMCLVA 206
D + T+ G+L + N+ ++ L + V+ +++ L + + E +
Sbjct: 78 HEDKIVRRNATMIFGILAS----NNDVKKLLRELDVMNSVIAQLAPE-EEVVIHEFASLC 132
Query: 207 FGNLAELESSKEQFASTNIAEELVKLFKKQIEHDKREMIFEVLAPLAENDAIKLQLVEAG 266
N++ +SK Q E L++L + D ++ E + L ++ + +L E
Sbjct: 133 LANMSAEYTSKVQIFEHGGLEPLIRLLSSP-DPDVKKNSMECIYNLVQDFQCRAKLQELN 191
Query: 267 LVECLLEIVQQK--------------VDSDKED--------------DITELKTGSDLMV 298
+ +L++++ + + +DKE I E K +DL +
Sbjct: 192 AIPPILDLLKSEYPVIQLLALKTLGVIANDKESRTMLRDNQGLDHLIKILETKELNDLHI 251
Query: 299 --LLLLGD--ESMQKLFEGGKGSVFQRVLSWIPSNN-HQLQLAGALAIANFARNDANCIH 353
L ++ + E M + + + +++LS+ ++ +Q A AI A + N
Sbjct: 252 EALAVIANCLEDMDTMVQIQQTGGLKKLLSFAENSTIPDIQKNAAKAITKAAYDPEN-RK 310
Query: 354 MVDNGIVEKLMDLLDRHVEDGNVTVQHAALSALRNLAIPVINKAKMLSAGVTEAV--LKF 411
+ VEK + L DG A+SA+ + +K + G+ + + LK
Sbjct: 311 LFHEQEVEKCLVALLGSENDGTKIAASQAISAMCENS---GSKDFFNNQGIPQLIQLLKS 367
Query: 412 LKSEMPPVQFKLLGTLRMLIDAQAEAAEQLGKNVKLVERLVEWCEAKDHAGVMGESNRLL 471
E+ L L A A AA + ++ L+ +K +
Sbjct: 368 DNEEVREAAALALANLTTCNPANANAAAEADG----IDPLINLLSSKRDGAIAN-----A 418
Query: 472 SALIRHSKSKDVIKTIVQSGGIKH-LVTMATSEHVIMQNEALVALALIAALELGTAEKDL 530
+ ++ + ++ ++ +Q+ I H +++ S + ++Q++A ALA+ A A +L
Sbjct: 419 ATVLTNMAMQEPLRLNIQNHDIMHAIISPLRSANTVVQSKA--ALAVTATACDVEARTEL 476
Query: 531 ESAKLVQILHRLLADERSAPEIKYNSMVLICALMGSECLHKEVQDLAFLDVVSKL 585
++ ++ L LL + + V++CA G E E+ L LD++ ++
Sbjct: 477 RNSGGLEPLVELLRSKNDEVRKHASWAVMVCA--GDELTANELCRLGALDILEEV 529
>gi|224589129 karyopherin 7 [Homo sapiens]
Length = 516
Score = 48.1 bits (113), Expect = 2e-05
Identities = 66/287 (22%), Positives = 117/287 (40%), Gaps = 26/287 (9%)
Query: 87 VDAGLISPLVQLLNSKDQEVLLQTGRALGNICYDSHEGRSAVDQAGGAQIVIDHLRSLCS 146
V+ G I PL++LL+S + V Q ALGNI D E R V + I HL +L S
Sbjct: 153 VEGGAIQPLIELLSSSNVAVCEQAVWALGNIAGDGPEFRDNVITSN----AIPHLLALIS 208
Query: 147 ITDPANEKLLTVFCGMLMNYSNENDSLQAQLINMGVIPTLVKLLGIHCQNAALTEMCLVA 206
T P L L N + ++P L+ LL H + L++ C A
Sbjct: 209 PTLPIT--FLRNITWTLSNLCRNKNPYPCDTAVKQILPALLHLLQ-HQDSEVLSDACW-A 264
Query: 207 FGNLAELESSK-EQFASTNIAEELVKLFKKQIEHDKREMIFEVLAPLAENDAIKLQLVEA 265
L + + + Q +T + LV L + + V + D ++A
Sbjct: 265 LSYLTDGSNKRIGQVVNTGVLPRLVVLMTSSELNVLTPSLRTVGNIVTGTDEQTQMAIDA 324
Query: 266 GLVECLLEIVQQKVDSDKED---DITELKTGSDLMVLLLLGDESMQKLFEGGKGSVFQRV 322
G++ L +++Q S +++ ++ + G + LL + V +
Sbjct: 325 GMLNVLPQLLQHNKPSIQKEAAWALSNVAAGPCHHIQQLLAYD------------VLPPL 372
Query: 323 LSWIPSNNHQLQLAGALAIANFARNDA--NCIHMVDNGIVEKLMDLL 367
++ + + ++Q +ANFA I +V +G++E L++LL
Sbjct: 373 VALLKNGEFKVQKEAVWMVANFATGATMDQLIQLVHSGVLEPLVNLL 419
>gi|31657114 armadillo repeat containing 4 [Homo sapiens]
Length = 1044
Score = 47.4 bits (111), Expect = 4e-05
Identities = 53/219 (24%), Positives = 91/219 (41%), Gaps = 17/219 (7%)
Query: 34 ALAQNNTETSEKIQASGILQLFASLL-TPQSSCKAKVANIIAEVAKNEFMRIPCVDAGLI 92
+LAQ + + I+ G L++ +LL T + CK I+ E++ N +R VD G +
Sbjct: 480 SLAQETCQLA--IRDVGGLEVLINLLETDEVKCKIGSLKILKEISHNPQIRQNIVDLGGL 537
Query: 93 SPLVQLLNSKDQEVLLQTGRALGNICYDSHEGRSAVDQAGGAQIVIDHLRSLCSITDPAN 152
+V +L+S + + + N+ R V Q GG ++ L T PA
Sbjct: 538 PIMVNILDSPHKSLKCLAAETIANVA-KFKRARRVVRQHGGITKLVALLDCAHDSTKPAQ 596
Query: 153 EKLL------TVFCGMLMNYSNENDSLQAQLI-NMGVIPTLVKLLGIHCQNAALTEMCLV 205
L CG L +S + I G IP L +LL +N M +
Sbjct: 597 SSLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLLKTSHEN-----MLIP 651
Query: 206 AFGNLAELESSKEQFASTNIAEELVKLFKKQIEHDKREM 244
G L E +S+E + + AE +++ K + + ++
Sbjct: 652 VVGTLQEC-ASEENYRAAIKAERIIENLVKNLNSENEQL 689
Score = 43.5 bits (101), Expect = 6e-04
Identities = 76/379 (20%), Positives = 153/379 (40%), Gaps = 40/379 (10%)
Query: 19 KTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFASLLTPQSSCKAKVANIIAEVAK 78
+ E E C + Q + ET + ++ G L+ ASLL + K ++A + + K
Sbjct: 685 ENEQLQEHCAMAIYQCA--EDKETRDLVRLHGGLKPLASLLNNTDN-KERLAAVTGAIWK 741
Query: 79 NEFMRIPCV---DAGLISPLVQLLNSKDQEVLLQTGRALGNICYDSHEGRSAVDQAGGAQ 135
+ + I LV LL + +EVL+ ALG C + E R V + GG Q
Sbjct: 742 CSISKENVTKFREYKAIETLVGLLTDQPEEVLVNVVGALGECCQE-RENRVIVRKCGGIQ 800
Query: 136 IVIDHLRSLCSITDPANEKLLTVFCGMLMNYSNENDSLQAQLINMGVIPTL--VKLLGIH 193
P L+ + +L+N + + + +M +I L V+LL
Sbjct: 801 --------------PLVNLLVGINQALLVNVTKAVGACAVEPESMMIIDRLDGVRLLWSL 846
Query: 194 CQNAALTEMCLVAFGNLAELESSKEQFASTNIAEELVKLFKKQIEHDKREMIFEVLAP-- 251
+N A+ ++++K+ ++L ++ D +E++ V A
Sbjct: 847 LKNPHPDVKASAAWALCPCIKNAKDAGEMVRSFVGGLELIVNLLKSDNKEVLASVCAAIT 906
Query: 252 -LAENDAIKLQLVEAGLVECLLEIVQQKVDSDKEDDITELKTGSDLMVLLLLGDESMQKL 310
+A++ + + G+V L ++ ++ ++ + + G +
Sbjct: 907 NIAKDQENLAVITDHGVVPLLSKL------ANTNNNKLRHHLAEAISRCCMWG----RNR 956
Query: 311 FEGGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARNDANCIHMVDNGIVEKLMDLLDRH 370
G+ ++ ++ SN+ + A A A+ + + NCI M +NG V+ L+D++
Sbjct: 957 VAFGEHKAVAPLVRYLKSNDTNVHRATAQALYQLSEDADNCITMHENGAVKLLLDMVGSP 1016
Query: 371 VEDGNVTVQHAALSALRNL 389
+D +Q AA + N+
Sbjct: 1017 DQD----LQEAAAGCISNI 1031
Score = 37.4 bits (85), Expect = 0.040
Identities = 83/417 (19%), Positives = 160/417 (38%), Gaps = 29/417 (6%)
Query: 1 MADNLSDTLKKLKITAVDKTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFASLLT 60
+ D D+ K + + + + + C L + ++++T +A GI L L T
Sbjct: 584 LLDCAHDSTKPAQSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLLKT 643
Query: 61 PQSSCKAKVANIIAEVAKNEFMRIPCVDAGLISPLVQLLNSKDQEVLLQTGRALGNICYD 120
+ V + E A E R +I LV+ LNS+++++ A+ C +
Sbjct: 644 SHENMLIPVVGTLQECASEENYRAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQ-CAE 702
Query: 121 SHEGRSAVDQAGGAQIVIDHLRSLCSITDPANEKLLTVFCGMLMNYSNENDSLQAQLINM 180
E R V GG + L SL + TD N++ L G + S +++ +
Sbjct: 703 DKETRDLVRLHGG----LKPLASLLNNTD--NKERLAAVTGAIWKCSISKENV-TKFREY 755
Query: 181 GVIPTLVKLLGIHCQNAALTEMCLVAFGNLAELESSKEQFASTNIAEELVKLFKKQIEHD 240
I TLV LL + + + A G + ++ + LV L +
Sbjct: 756 KAIETLVGLLTDQPEEVLVN--VVGALGECCQERENRVIVRKCGGIQPLVNLLVGINQAL 813
Query: 241 KREMIFEVLAPLAENDAIKL--QLVEAGLVECLLEIVQQKVDSDKEDDITE-LKTGSDLM 297
+ V A E +++ + +L L+ LL+ V + + +K D
Sbjct: 814 LVNVTKAVGACAVEPESMMIIDRLDGVRLLWSLLKNPHPDVKASAAWALCPCIKNAKDA- 872
Query: 298 VLLLLGDESMQKLFEGGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARNDANCIHMVDN 357
M + F GG + +++ + S+N ++ + AI N A++ N + D+
Sbjct: 873 -------GEMVRSFVGG----LELIVNLLKSDNKEVLASVCAAITNIAKDQENLAVITDH 921
Query: 358 GIVEKLMDLLDRHVEDGNVTVQHAALSALRNLAIPVINKAKMLSAGVTEAVLKFLKS 414
G+V LL + N ++H A+ + N+ ++++LKS
Sbjct: 922 GVV----PLLSKLANTNNNKLRHHLAEAISRCCMWGRNRVAFGEHKAVAPLVRYLKS 974
>gi|39812229 karyopherin alpha 5 [Homo sapiens]
Length = 539
Score = 46.2 bits (108), Expect = 9e-05
Identities = 66/280 (23%), Positives = 116/280 (41%), Gaps = 44/280 (15%)
Query: 39 NTETSEKIQASGILQLFASLLTPQSSC--KAKVANIIAEVAKNEFMRIPCV-DAGLISPL 95
N + IQ G++Q F L +C + + A + +A F+ V + G +
Sbjct: 116 NPPIDQVIQKPGVVQRFVKFLERNENCTLQFEAAWALTNIASGTFLHTKVVIETGAVPIF 175
Query: 96 VQLLNSKDQEVLLQTGRALGNICYDSHEGRSAV----------------DQAGGAQIVID 139
++LLNS+ ++V Q ALGNI D+ E R V ++ + +
Sbjct: 176 IKLLNSEHEDVQEQAVWALGNIAGDNAECRDFVLNCEILPPLLELLTNSNRLTTTRNAVW 235
Query: 140 HLRSLCSITDP--------------------ANEKLLTVFCGMLMNYSN-ENDSLQAQLI 178
L +LC +P ++ +L C L S+ ND +QA +I
Sbjct: 236 ALSNLCRGKNPPPNFSKVSPCLNVLSRLLFSSDPDVLADVCWALSYLSDGPNDKIQA-VI 294
Query: 179 NMGVIPTLVKLLGIHCQNAALTEMCLVAFGNLAELESSKEQ-FASTNIAEELVKLFKKQI 237
+ GV LV+LL +H + + L A GN+ + + Q + + L+ L
Sbjct: 295 DSGVCRRLVELL-MH-NDYKVVSPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPK 352
Query: 238 EHDKREMIFEVLAPLAENDAIKLQLVEAGLVECLLEIVQQ 277
E ++E + V A N A +++A + L+EI+Q+
Sbjct: 353 ESIRKEACWTVSNITAGNRAQIQAVIDANIFPVLIEILQK 392
>gi|4504897 karyopherin alpha 2 [Homo sapiens]
Length = 529
Score = 43.9 bits (102), Expect = 4e-04
Identities = 96/439 (21%), Positives = 168/439 (38%), Gaps = 85/439 (19%)
Query: 35 LAQNNTETSEKIQASGILQLFASLL--TPQSSCKAKVANIIAEVAKNEFMRIPCV-DAGL 91
L++ + I +G++ F S L T S + + A + +A + V D G
Sbjct: 104 LSREKQPPIDNIIRAGLIPKFVSFLGRTDCSPIQFESAWALTNIASGTSEQTKAVVDGGA 163
Query: 92 ISPLVQLLNSKDQEVLLQTGRALGNICYDSHEGRSAVDQAGGAQIVIDHLRSLCSITDPA 151
I + LL S + Q ALGNI D R V + G +D L +L ++ D
Sbjct: 164 IPAFISLLASPHAHISEQAVWALGNIAGDGSVFRDLVIKYG----AVDPLLALLAVPD-- 217
Query: 152 NEKLLTVFCGMLMNYS--------NENDSLQAQLINMGVIPTLVKLLGIHCQNAALTEMC 203
+ ++ CG L N + N+N + + ++PTLV+LL H L + C
Sbjct: 218 ---MSSLACGYLRNLTWTLSNLCRNKNPAPPIDAVEQ-ILPTLVRLLH-HDDPEVLADTC 272
Query: 204 LVAFGNLAELESSK-EQFASTNIAEELVKLFKKQIEHDKREMIFEVLAPLAENDAIKLQL 262
A L + + + T + +LVKL A +L +
Sbjct: 273 W-AISYLTDGPNERIGMVVKTGVVPQLVKLL----------------------GASELPI 309
Query: 263 VEAGLVECLLEIVQQKVDSDKEDDITELKTGSDLMVLLLLGDESMQKLFEGGKGSVFQRV 322
V L I + TG+ DE Q + + G +VF +
Sbjct: 310 VTPAL-----------------RAIGNIVTGT---------DEQTQVVIDAGALAVFPSL 343
Query: 323 LSWIPSNNHQLQLAGALAIANFARNDANCIHMVDNGIVEKLMDLLDRHVEDGNVTVQHAA 382
L+ P N Q + ++ R D +V++G+V L+ +L + + Q A
Sbjct: 344 LT-NPKTNIQKEATWTMSNITAGRQD-QIQQVVNHGLVPFLVSVLSK----ADFKTQKEA 397
Query: 383 LSALRNLAI--PVINKAKMLSAGVTEAVLKFLKSEMPPVQFKLLGTLRMLIDAQAEAAEQ 440
+ A+ N V ++ G+ E ++ L ++ + +L + + +AAE+
Sbjct: 398 VWAVTNYTSGGTVEQIVYLVHCGIIEPLMNLLTAKDTKIILVILDAISNIF----QAAEK 453
Query: 441 LGKNVKLVERLVEWCEAKD 459
LG+ KL ++E C D
Sbjct: 454 LGETEKL-SIMIEECGGLD 471
>gi|11034811 catenin (cadherin-associated protein), delta 2 (neural
plakophilin-related arm-repeat protein) [Homo sapiens]
Length = 1225
Score = 40.0 bits (92), Expect = 0.006
Identities = 26/98 (26%), Positives = 47/98 (47%), Gaps = 9/98 (9%)
Query: 95 LVQLLNSKDQEVLLQTGRALGNICYDSHEGRSAVDQAGGAQIVIDHLRSLCSITDPANEK 154
++Q+L + V L ++C+ ++ ++ + + GG Q+++D + D +
Sbjct: 555 VIQMLQHQFPSVQSNAAAYLQHLCFGDNKIKAEIRRQGGIQLLVD-------LLDHRMTE 607
Query: 155 LLTVFCGMLMN--YSNENDSLQAQLINMGVIPTLVKLL 190
+ CG L N Y ND + L N G IP LV+LL
Sbjct: 608 VHRSACGALRNLVYGKANDDNKIALKNCGGIPALVRLL 645
>gi|94536840 transmembrane and coiled-coil domains 6 [Homo sapiens]
Length = 493
Score = 39.3 bits (90), Expect = 0.011
Identities = 49/218 (22%), Positives = 87/218 (39%), Gaps = 34/218 (15%)
Query: 18 DKTEDSLEGCLDCLL------QALAQNNTETSEKIQASGILQLFASLLTPQSSCKAKVAN 71
D E++ EGC+ +L Q L Q T EK + ++ L L P++
Sbjct: 48 DAPEEAGEGCVAAILGETEVQQFLRQAQRGTEEKEREGALVSLRRGLQHPET-------- 99
Query: 72 IIAEVAKNEFMRIPCVDAGLISPLVQLLNSKDQEVLLQTGRALGNICYDSHEGRSAVDQA 131
+ F+R+ G + LV LL S + L+ R L + SH +S V
Sbjct: 100 ------QQTFIRLE----GSMRTLVGLLTSNQALLQLEAARCLHEL---SHSEQSTV--- 143
Query: 132 GGAQIVIDHLRSLCSITDPANEKLLTVFCGMLMNYSNENDSLQAQLINMGVIPTLVKLLG 191
A+ + L + + + + L N E+++++ QL+ G++P L
Sbjct: 144 --AEACLPATSYLLTYLSSHSSDFIELCLYTLGNLIVESEAVRRQLLPQGIVPALAAC-- 199
Query: 192 IHCQNAALTEMCLVAFGNLAELESSKEQFASTNIAEEL 229
I + A+ E A L + E + E+ + +A L
Sbjct: 200 IQSPHVAVLEALGYALSQLLQAEEAPEKIIPSILASTL 237
>gi|91206450 ankyrin and armadillo repeat containing [Homo sapiens]
Length = 1363
Score = 38.1 bits (87), Expect = 0.024
Identities = 90/445 (20%), Positives = 180/445 (40%), Gaps = 60/445 (13%)
Query: 170 NDSLQAQLINMGVIPTLVKLL-----GIHCQNAALTEMCLVAFGNLAELESSKEQFASTN 224
ND +++ G IP L+ LL + C+ L N++ +S+
Sbjct: 660 NDQYWRCILDAGTIPALINLLKSSKIKLQCKTVGL-------LSNISTHKSAVHALVEAG 712
Query: 225 IAEELVKLF--KKQIEHDKREMIFEVLAPLAENDAIKLQLVEAGLVECLLEIVQQKVDSD 282
L+ L + H + +I +A D I + + L+ ++ +++
Sbjct: 713 GIPSLINLLVCDEPEVHSRCAVILYDIAQCENKDVI----AKYNGIPSLINLLNLNIEN- 767
Query: 283 KEDDITELKTGSDLMVLLLLGDESMQKLFEGGKGSVFQRVLSWIPSNNHQLQLAGALAIA 342
L + + +L +G+E+ Q+ KG + ++ ++ S++ L+ + AIA
Sbjct: 768 ------VLVNVMNCIRVLCIGNENNQRAVREHKGLPY--LIRFLSSDSDVLKAVSSAAIA 819
Query: 343 NFARNDANCIHMVD-NGIVEKLMDLLDRHVEDGNVTVQHAALSALRNLAI--PVINKAKM 399
R++ + G + L+ L + ++VQ A+ +LA +I KA
Sbjct: 820 EVGRDNKEIQDAIAMEGAIPPLVALF----KGKQISVQMKGAMAVESLASHNALIQKA-F 874
Query: 400 LSAGVTEAVLKFLKSEMPPVQ----FKLLGTLRMLIDAQAEAAEQLGKNVKLVERLVEWC 455
L +T+ +LK LK+ V+ L + Q AEQ+G + ++ L+
Sbjct: 875 LEKSLTKYLLKLLKAFQIDVKEQGAVALWALAGQTLKQQKYMAEQIGYSF-IINMLLSPS 933
Query: 456 EAKDHAGVMGESNRLLSALIRHSKSKDVIKTIVQSGGIKHLVTMATSEHVIMQNEALVAL 515
+ G GE+ LS R +++ I + GI LV + I + L +
Sbjct: 934 AKMQYVG--GEAVIALSKDSRMHQNQ-----ICEGNGIAPLVRLLRIS-TIAEGTLLSVI 985
Query: 516 ALIAALELGTA-------EKDLESAKLVQILHRLLADERSAPEIKYN-SMVLICALMGSE 567
+ ++ +G A ++ + +L +LL + S P IK + L C ++G++
Sbjct: 986 RAVGSICIGVAHTSNPVSQQFVVDENAFPVLIQLLRNHPS-PNIKVEVAFSLACIVLGND 1044
Query: 568 CLHKEVQD---LAFLDVVSKLRSHE 589
L K++ + + DV+ L S E
Sbjct: 1045 VLQKDLHENEGFEYADVLYLLHSTE 1069
>gi|4504811 junction plakoglobin [Homo sapiens]
Length = 745
Score = 37.7 bits (86), Expect = 0.031
Identities = 91/422 (21%), Positives = 159/422 (37%), Gaps = 65/422 (15%)
Query: 92 ISPLVQLLNSKDQEVLLQTGRALGNICYDSHEGRSAVDQAGGAQIVIDHLRSLCSITDPA 151
+ +V LLN + + L T L + Y + E + + GG Q ++ +R+ +
Sbjct: 270 LQKMVPLLNKNNPKFLAITTDCLQLLAYGNQESKLIILANGGPQALVQIMRNY------S 323
Query: 152 NEKLLTVFCGMLMNYSNENDSLQAQLINMGVIPTLVKLLGIHCQNAALTEMCLVAFGNLA 211
EKLL ++ + S + ++ G + L K L + L + CL NL+
Sbjct: 324 YEKLLWT-TSRVLKVLSVCPSNKPAIVEAGGMQALGKHL--TSNSPRLVQNCLWTLRNLS 380
Query: 212 ELESSKEQFASTNIAEELVKLFKKQIEHDKREMIFEVLAPLA----ENDAIKLQLVEAGL 267
++ + +E E ++K+ Q+ D ++ L+ N K + +
Sbjct: 381 DVATKQEGL------ESVLKILVNQLSVDDVNVLTCATGTLSNLTCNNSKNKTLVTQNSG 434
Query: 268 VECLLEIVQQKVDSDKEDDITELKTGSDLMVLLLLGDESMQKLFEGGKGSVFQRVLSWIP 327
VE L+ + + D +DDITE V L S E + SV R+ IP
Sbjct: 435 VEALIHAILRAGD---KDDITE------PAVCALRHLTSRHPEAEMAQNSV--RLNYGIP 483
Query: 328 S--------NNHQLQLAGALAIANFARNDANCIHMVDNGIVEKLMDLL-------DRHVE 372
+ N L A I N A AN + + ++ +L+ LL RHV
Sbjct: 484 AIVKLLNQPNQWPLVKATIGLIRNLALCPANHAPLQEAAVIPRLVQLLVKAHQDAQRHVA 543
Query: 373 DGN----------VTVQHAALSALRNLAIPVINKAKMLSAGVTEAVLKFLKSEMPPVQFK 422
G + AL LA +N+ ++ ++ L S + +Q
Sbjct: 544 AGTQQPYTDGVRMEEIVEGCTGALHILARDPMNRMEIFRLNTIPLFVQLLYSSVENIQRV 603
Query: 423 LLGTLRMLIDAQ--AEAAEQLGKNVKLVERLVEWCEAKDHAGVMGESNRLLSALIRHSKS 480
G L L + A+A + G + L+E L H+ G + + L R S+
Sbjct: 604 AAGVLCELAQDKEAADAIDAEGASAPLMELL--------HSRNEGTATYAAAVLFRISED 655
Query: 481 KD 482
K+
Sbjct: 656 KN 657
>gi|12056468 junction plakoglobin [Homo sapiens]
Length = 745
Score = 37.7 bits (86), Expect = 0.031
Identities = 91/422 (21%), Positives = 159/422 (37%), Gaps = 65/422 (15%)
Query: 92 ISPLVQLLNSKDQEVLLQTGRALGNICYDSHEGRSAVDQAGGAQIVIDHLRSLCSITDPA 151
+ +V LLN + + L T L + Y + E + + GG Q ++ +R+ +
Sbjct: 270 LQKMVPLLNKNNPKFLAITTDCLQLLAYGNQESKLIILANGGPQALVQIMRNY------S 323
Query: 152 NEKLLTVFCGMLMNYSNENDSLQAQLINMGVIPTLVKLLGIHCQNAALTEMCLVAFGNLA 211
EKLL ++ + S + ++ G + L K L + L + CL NL+
Sbjct: 324 YEKLLWT-TSRVLKVLSVCPSNKPAIVEAGGMQALGKHL--TSNSPRLVQNCLWTLRNLS 380
Query: 212 ELESSKEQFASTNIAEELVKLFKKQIEHDKREMIFEVLAPLA----ENDAIKLQLVEAGL 267
++ + +E E ++K+ Q+ D ++ L+ N K + +
Sbjct: 381 DVATKQEGL------ESVLKILVNQLSVDDVNVLTCATGTLSNLTCNNSKNKTLVTQNSG 434
Query: 268 VECLLEIVQQKVDSDKEDDITELKTGSDLMVLLLLGDESMQKLFEGGKGSVFQRVLSWIP 327
VE L+ + + D +DDITE V L S E + SV R+ IP
Sbjct: 435 VEALIHAILRAGD---KDDITE------PAVCALRHLTSRHPEAEMAQNSV--RLNYGIP 483
Query: 328 S--------NNHQLQLAGALAIANFARNDANCIHMVDNGIVEKLMDLL-------DRHVE 372
+ N L A I N A AN + + ++ +L+ LL RHV
Sbjct: 484 AIVKLLNQPNQWPLVKATIGLIRNLALCPANHAPLQEAAVIPRLVQLLVKAHQDAQRHVA 543
Query: 373 DGN----------VTVQHAALSALRNLAIPVINKAKMLSAGVTEAVLKFLKSEMPPVQFK 422
G + AL LA +N+ ++ ++ L S + +Q
Sbjct: 544 AGTQQPYTDGVRMEEIVEGCTGALHILARDPMNRMEIFRLNTIPLFVQLLYSSVENIQRV 603
Query: 423 LLGTLRMLIDAQ--AEAAEQLGKNVKLVERLVEWCEAKDHAGVMGESNRLLSALIRHSKS 480
G L L + A+A + G + L+E L H+ G + + L R S+
Sbjct: 604 AAGVLCELAQDKEAADAIDAEGASAPLMELL--------HSRNEGTATYAAAVLFRISED 655
Query: 481 KD 482
K+
Sbjct: 656 KN 657
>gi|6912678 sperm associated antigen 6 isoform 1 [Homo sapiens]
Length = 509
Score = 37.7 bits (86), Expect = 0.031
Identities = 29/134 (21%), Positives = 61/134 (45%), Gaps = 2/134 (1%)
Query: 12 LKITAVDKTEDSLEGCLDCLLQALAQNNTETSEKI-QASGILQLFASLLTPQSSCKAKVA 70
L + + + E +L+ L +A+++ E ++ + A + L +L P + K ++
Sbjct: 171 LLVLCIQEPEIALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMILNPDAKLKHQIL 230
Query: 71 NIIAEVAKNEF-MRIPCVDAGLISPLVQLLNSKDQEVLLQTGRALGNICYDSHEGRSAVD 129
+ +++V+K+ + V+A + ++ L KD+ V + I + E V
Sbjct: 231 SALSQVSKHSVDLAEMVVEAEIFPVVLTCLKDKDEYVKKNASTLIREIAKHTPELSQLVV 290
Query: 130 QAGGAQIVIDHLRS 143
AGG VID + S
Sbjct: 291 NAGGVAAVIDCIGS 304
Score = 31.6 bits (70), Expect = 2.2
Identities = 23/90 (25%), Positives = 48/90 (53%), Gaps = 5/90 (5%)
Query: 471 LSALIRHSKSKDVIKTIVQSGGIKHLVTMATSEHVIMQNEALVALALIAALELGTAEKDL 530
LS + +HS ++ +T+V +G + HL M + ++++ L AL+ ++ + AE +
Sbjct: 191 LSDIAKHSP--ELAQTVVDAGAVAHLAQMILNPDAKLKHQILSALSQVSKHSVDLAEMVV 248
Query: 531 ESAKLVQILHRLLADERSAPEIKYNSMVLI 560
E A++ ++ L D+ +K N+ LI
Sbjct: 249 E-AEIFPVVLTCLKDKDE--YVKKNASTLI 275
>gi|27262641 sperm associated antigen 6 isoform 2 [Homo sapiens]
Length = 458
Score = 37.7 bits (86), Expect = 0.031
Identities = 29/134 (21%), Positives = 61/134 (45%), Gaps = 2/134 (1%)
Query: 12 LKITAVDKTEDSLEGCLDCLLQALAQNNTETSEKI-QASGILQLFASLLTPQSSCKAKVA 70
L + + + E +L+ L +A+++ E ++ + A + L +L P + K ++
Sbjct: 171 LLVLCIQEPEIALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMILNPDAKLKHQIL 230
Query: 71 NIIAEVAKNEF-MRIPCVDAGLISPLVQLLNSKDQEVLLQTGRALGNICYDSHEGRSAVD 129
+ +++V+K+ + V+A + ++ L KD+ V + I + E V
Sbjct: 231 SALSQVSKHSVDLAEMVVEAEIFPVVLTCLKDKDEYVKKNASTLIREIAKHTPELSQLVV 290
Query: 130 QAGGAQIVIDHLRS 143
AGG VID + S
Sbjct: 291 NAGGVAAVIDCIGS 304
Score = 31.6 bits (70), Expect = 2.2
Identities = 23/90 (25%), Positives = 48/90 (53%), Gaps = 5/90 (5%)
Query: 471 LSALIRHSKSKDVIKTIVQSGGIKHLVTMATSEHVIMQNEALVALALIAALELGTAEKDL 530
LS + +HS ++ +T+V +G + HL M + ++++ L AL+ ++ + AE +
Sbjct: 191 LSDIAKHSP--ELAQTVVDAGAVAHLAQMILNPDAKLKHQILSALSQVSKHSVDLAEMVV 248
Query: 531 ESAKLVQILHRLLADERSAPEIKYNSMVLI 560
E A++ ++ L D+ +K N+ LI
Sbjct: 249 E-AEIFPVVLTCLKDKDE--YVKKNASTLI 275
>gi|148227672 catenin (cadherin-associated protein), beta 1, 88kDa
[Homo sapiens]
Length = 781
Score = 37.0 bits (84), Expect = 0.053
Identities = 42/170 (24%), Positives = 73/170 (42%), Gaps = 24/170 (14%)
Query: 31 LLQALAQNNTETSEKIQASGILQLFASLLTPQS----SCKAKVANIIAEVAKNEFMRIPC 86
+L+ L+ ++ ++A G+ L L P +C + N+ K E M
Sbjct: 343 VLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGME--- 399
Query: 87 VDAGLISPLVQLLNSKDQEVLLQTGRALGNICYDSHEGRSAVDQAGGAQIVIDHLRSLC- 145
GL+ LVQLL S D V+ L N+ ++++ + V Q GG + ++ +
Sbjct: 400 ---GLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGD 456
Query: 146 --SITDPANEKLLTVFCGMLMNYSNENDSLQAQ---LINMGVIPTLVKLL 190
IT+PA C + S ++ AQ ++ G +P +VKLL
Sbjct: 457 REDITEPA-------ICALRHLTSRHQEAEMAQNAVRLHYG-LPVVVKLL 498
Score = 32.7 bits (73), Expect = 1.00
Identities = 95/422 (22%), Positives = 159/422 (37%), Gaps = 60/422 (14%)
Query: 89 AGLISPLVQLLNSKDQEVLLQTGRALGNICYDSHEGRSAVDQAGGAQIVIDHLRSLCSIT 148
AG + +V LLN + + L T L + Y + E + + +GG Q +++ +R+
Sbjct: 276 AGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRTY---- 331
Query: 149 DPANEKLLTVFCGMLMNYSNENDSLQAQLINMGVIPTLVKLLGIHCQNAA--LTEMCLVA 206
EKLL +L S + + A + G ++ LG+H + + L + CL
Sbjct: 332 --TYEKLLWTTSRVLKVLSVCSSNKPAIVEAGG-----MQALGLHLTDPSQRLVQNCLWT 384
Query: 207 FGNLAELESSKEQFASTNIAEELVKLFKKQIEHDKREMIFEVLAPL-AENDAIKLQLVEA 265
NL++ + +E + LV+L + + +L+ L N K+ + +
Sbjct: 385 LRNLSDAATKQE--GMEGLLGTLVQLLGSD-DINVVTCAAGILSNLTCNNYKNKMMVCQV 441
Query: 266 GLVECLLEIVQQKVDSDKEDDITELKTGSDLMVLLLLGDESMQKLFEGGKGSVFQR---- 321
G +E L+ V + D +DITE + L S + E + +V
Sbjct: 442 GGIEALVRTVLRAGD---REDITE------PAICALRHLTSRHQEAEMAQNAVRLHYGLP 492
Query: 322 --VLSWIPSNNHQLQLAGALAIANFARNDANCIHMVDNGIVEKLMDLLDRHVED------ 373
V P ++ L A I N A AN + + G + +L+ LL R +D
Sbjct: 493 VVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAHQDTQRRTS 552
Query: 374 -GNVTVQ-----------HAALSALRNLAIPVINKAKMLSAGVTEAVLKFLKSEMPPVQF 421
G Q AL LA V N+ + ++ L S + +Q
Sbjct: 553 MGGTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFVQLLYSPIENIQR 612
Query: 422 KLLGTLRMLIDAQ--AEAAEQLGKNVKLVERLVEWCEAKDHAGVMGESNRLLSALIRHSK 479
G L L + AEA E G L E L H+ G + + L R S+
Sbjct: 613 VAAGVLCELAQDKEAAEAIEAEGATAPLTELL--------HSRNEGVATYAAAVLFRMSE 664
Query: 480 SK 481
K
Sbjct: 665 DK 666
Score = 30.0 bits (66), Expect = 6.5
Identities = 31/113 (27%), Positives = 51/113 (45%), Gaps = 10/113 (8%)
Query: 79 NEFMRIPCVDAGLISPLVQLLNSKDQEVLLQTGRALGNICYDSHEGRSAVDQAGGAQIVI 138
N+ ++ + +G LV ++ + E LL T + + + A+ +AGG Q +
Sbjct: 308 NQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALG 367
Query: 139 DHLRSLCSITDPANEKLLTVFCGMLMNYSNENDSLQAQLINMGVIPTLVKLLG 191
HL TDP+ L C L N +D+ Q G++ TLV+LLG
Sbjct: 368 LHL------TDPSQR--LVQNC--LWTLRNLSDAATKQEGMEGLLGTLVQLLG 410
>gi|148233338 catenin (cadherin-associated protein), beta 1, 88kDa
[Homo sapiens]
Length = 781
Score = 37.0 bits (84), Expect = 0.053
Identities = 42/170 (24%), Positives = 73/170 (42%), Gaps = 24/170 (14%)
Query: 31 LLQALAQNNTETSEKIQASGILQLFASLLTPQS----SCKAKVANIIAEVAKNEFMRIPC 86
+L+ L+ ++ ++A G+ L L P +C + N+ K E M
Sbjct: 343 VLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGME--- 399
Query: 87 VDAGLISPLVQLLNSKDQEVLLQTGRALGNICYDSHEGRSAVDQAGGAQIVIDHLRSLC- 145
GL+ LVQLL S D V+ L N+ ++++ + V Q GG + ++ +
Sbjct: 400 ---GLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGD 456
Query: 146 --SITDPANEKLLTVFCGMLMNYSNENDSLQAQ---LINMGVIPTLVKLL 190
IT+PA C + S ++ AQ ++ G +P +VKLL
Sbjct: 457 REDITEPA-------ICALRHLTSRHQEAEMAQNAVRLHYG-LPVVVKLL 498
Score = 32.7 bits (73), Expect = 1.00
Identities = 95/422 (22%), Positives = 159/422 (37%), Gaps = 60/422 (14%)
Query: 89 AGLISPLVQLLNSKDQEVLLQTGRALGNICYDSHEGRSAVDQAGGAQIVIDHLRSLCSIT 148
AG + +V LLN + + L T L + Y + E + + +GG Q +++ +R+
Sbjct: 276 AGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRTY---- 331
Query: 149 DPANEKLLTVFCGMLMNYSNENDSLQAQLINMGVIPTLVKLLGIHCQNAA--LTEMCLVA 206
EKLL +L S + + A + G ++ LG+H + + L + CL
Sbjct: 332 --TYEKLLWTTSRVLKVLSVCSSNKPAIVEAGG-----MQALGLHLTDPSQRLVQNCLWT 384
Query: 207 FGNLAELESSKEQFASTNIAEELVKLFKKQIEHDKREMIFEVLAPL-AENDAIKLQLVEA 265
NL++ + +E + LV+L + + +L+ L N K+ + +
Sbjct: 385 LRNLSDAATKQE--GMEGLLGTLVQLLGSD-DINVVTCAAGILSNLTCNNYKNKMMVCQV 441
Query: 266 GLVECLLEIVQQKVDSDKEDDITELKTGSDLMVLLLLGDESMQKLFEGGKGSVFQR---- 321
G +E L+ V + D +DITE + L S + E + +V
Sbjct: 442 GGIEALVRTVLRAGD---REDITE------PAICALRHLTSRHQEAEMAQNAVRLHYGLP 492
Query: 322 --VLSWIPSNNHQLQLAGALAIANFARNDANCIHMVDNGIVEKLMDLLDRHVED------ 373
V P ++ L A I N A AN + + G + +L+ LL R +D
Sbjct: 493 VVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAHQDTQRRTS 552
Query: 374 -GNVTVQ-----------HAALSALRNLAIPVINKAKMLSAGVTEAVLKFLKSEMPPVQF 421
G Q AL LA V N+ + ++ L S + +Q
Sbjct: 553 MGGTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFVQLLYSPIENIQR 612
Query: 422 KLLGTLRMLIDAQ--AEAAEQLGKNVKLVERLVEWCEAKDHAGVMGESNRLLSALIRHSK 479
G L L + AEA E G L E L H+ G + + L R S+
Sbjct: 613 VAAGVLCELAQDKEAAEAIEAEGATAPLTELL--------HSRNEGVATYAAAVLFRMSE 664
Query: 480 SK 481
K
Sbjct: 665 DK 666
Score = 30.0 bits (66), Expect = 6.5
Identities = 31/113 (27%), Positives = 51/113 (45%), Gaps = 10/113 (8%)
Query: 79 NEFMRIPCVDAGLISPLVQLLNSKDQEVLLQTGRALGNICYDSHEGRSAVDQAGGAQIVI 138
N+ ++ + +G LV ++ + E LL T + + + A+ +AGG Q +
Sbjct: 308 NQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALG 367
Query: 139 DHLRSLCSITDPANEKLLTVFCGMLMNYSNENDSLQAQLINMGVIPTLVKLLG 191
HL TDP+ L C L N +D+ Q G++ TLV+LLG
Sbjct: 368 LHL------TDPSQR--LVQNC--LWTLRNLSDAATKQEGMEGLLGTLVQLLG 410
>gi|4503131 catenin (cadherin-associated protein), beta 1, 88kDa
[Homo sapiens]
Length = 781
Score = 37.0 bits (84), Expect = 0.053
Identities = 42/170 (24%), Positives = 73/170 (42%), Gaps = 24/170 (14%)
Query: 31 LLQALAQNNTETSEKIQASGILQLFASLLTPQS----SCKAKVANIIAEVAKNEFMRIPC 86
+L+ L+ ++ ++A G+ L L P +C + N+ K E M
Sbjct: 343 VLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGME--- 399
Query: 87 VDAGLISPLVQLLNSKDQEVLLQTGRALGNICYDSHEGRSAVDQAGGAQIVIDHLRSLC- 145
GL+ LVQLL S D V+ L N+ ++++ + V Q GG + ++ +
Sbjct: 400 ---GLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGD 456
Query: 146 --SITDPANEKLLTVFCGMLMNYSNENDSLQAQ---LINMGVIPTLVKLL 190
IT+PA C + S ++ AQ ++ G +P +VKLL
Sbjct: 457 REDITEPA-------ICALRHLTSRHQEAEMAQNAVRLHYG-LPVVVKLL 498
Score = 32.7 bits (73), Expect = 1.00
Identities = 95/422 (22%), Positives = 159/422 (37%), Gaps = 60/422 (14%)
Query: 89 AGLISPLVQLLNSKDQEVLLQTGRALGNICYDSHEGRSAVDQAGGAQIVIDHLRSLCSIT 148
AG + +V LLN + + L T L + Y + E + + +GG Q +++ +R+
Sbjct: 276 AGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRTY---- 331
Query: 149 DPANEKLLTVFCGMLMNYSNENDSLQAQLINMGVIPTLVKLLGIHCQNAA--LTEMCLVA 206
EKLL +L S + + A + G ++ LG+H + + L + CL
Sbjct: 332 --TYEKLLWTTSRVLKVLSVCSSNKPAIVEAGG-----MQALGLHLTDPSQRLVQNCLWT 384
Query: 207 FGNLAELESSKEQFASTNIAEELVKLFKKQIEHDKREMIFEVLAPL-AENDAIKLQLVEA 265
NL++ + +E + LV+L + + +L+ L N K+ + +
Sbjct: 385 LRNLSDAATKQE--GMEGLLGTLVQLLGSD-DINVVTCAAGILSNLTCNNYKNKMMVCQV 441
Query: 266 GLVECLLEIVQQKVDSDKEDDITELKTGSDLMVLLLLGDESMQKLFEGGKGSVFQR---- 321
G +E L+ V + D +DITE + L S + E + +V
Sbjct: 442 GGIEALVRTVLRAGD---REDITE------PAICALRHLTSRHQEAEMAQNAVRLHYGLP 492
Query: 322 --VLSWIPSNNHQLQLAGALAIANFARNDANCIHMVDNGIVEKLMDLLDRHVED------ 373
V P ++ L A I N A AN + + G + +L+ LL R +D
Sbjct: 493 VVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAHQDTQRRTS 552
Query: 374 -GNVTVQ-----------HAALSALRNLAIPVINKAKMLSAGVTEAVLKFLKSEMPPVQF 421
G Q AL LA V N+ + ++ L S + +Q
Sbjct: 553 MGGTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFVQLLYSPIENIQR 612
Query: 422 KLLGTLRMLIDAQ--AEAAEQLGKNVKLVERLVEWCEAKDHAGVMGESNRLLSALIRHSK 479
G L L + AEA E G L E L H+ G + + L R S+
Sbjct: 613 VAAGVLCELAQDKEAAEAIEAEGATAPLTELL--------HSRNEGVATYAAAVLFRMSE 664
Query: 480 SK 481
K
Sbjct: 665 DK 666
Score = 30.0 bits (66), Expect = 6.5
Identities = 31/113 (27%), Positives = 51/113 (45%), Gaps = 10/113 (8%)
Query: 79 NEFMRIPCVDAGLISPLVQLLNSKDQEVLLQTGRALGNICYDSHEGRSAVDQAGGAQIVI 138
N+ ++ + +G LV ++ + E LL T + + + A+ +AGG Q +
Sbjct: 308 NQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALG 367
Query: 139 DHLRSLCSITDPANEKLLTVFCGMLMNYSNENDSLQAQLINMGVIPTLVKLLG 191
HL TDP+ L C L N +D+ Q G++ TLV+LLG
Sbjct: 368 LHL------TDPSQR--LVQNC--LWTLRNLSDAATKQEGMEGLLGTLVQLLG 410
>gi|15529984 armadillo repeat containing 6 [Homo sapiens]
Length = 476
Score = 36.6 bits (83), Expect = 0.069
Identities = 56/228 (24%), Positives = 95/228 (41%), Gaps = 12/228 (5%)
Query: 388 NLAIPVINKAKMLSAGVTEAVLKFLKSEMPPVQFKLLGTLRMLIDAQAEAAE--QLGKNV 445
N A ++ + K L + EA FL + P + +L GTL L E LG
Sbjct: 239 NHAKMIVQENKGLKV-LIEATKAFLDN--PGILSELCGTLSRLAIRNEFCQEVVDLGGLS 295
Query: 446 KLVERLVEWC---EAKDHAGVMGESNRLLSALIRHSKSKDVIKTIVQSGGIKHLVTMATS 502
LV L + C + +D +GV ++LS L + + DV IV++GG + +V T
Sbjct: 296 ILVSLLAD-CNDHQMRDQSGVQELVKQVLSTLRAIAGNDDVKDAIVRAGGTESIVAAMTQ 354
Query: 503 EHVIMQ--NEALVALALIAALELGTAEKDLESAKLVQILHRLLADERSAPEIKYNSMVLI 560
Q ++ AL +A + + +E V L + A + A K M++
Sbjct: 355 HLTSPQVCEQSCAALCFLALRKPDNSRIIVEGGGAVAALQAMKAHPQKAGVQKQACMLIR 414
Query: 561 CALMGSECLHKEVQDLAFLDVVSKLRS-HENKSVAQQASLTEQRLTVE 607
+ + K + DL ++ + RS H + +A+L + VE
Sbjct: 415 NLVAHGQAFSKPILDLGAEALIMQARSAHRDCEDVAKAALRDLGCHVE 462
>gi|7106299 ataxin 10 [Homo sapiens]
Length = 475
Score = 35.8 bits (81), Expect = 0.12
Identities = 40/187 (21%), Positives = 80/187 (42%), Gaps = 18/187 (9%)
Query: 12 LKITAVDKTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFASLLTPQSSCKAKVAN 71
LK+ + + +D LL L + T + G LQ+F LL +V +
Sbjct: 287 LKLASEEPPDDEEALATIRLLDVLCEMTVNT----ELLGYLQVFPGLLERVIDL-LRVIH 341
Query: 72 IIAEVAKNEFMRIPCVDAGLISPLVQLLNSKDQEVLLQTGRALGNICYDSHEGRSAVDQA 131
+ + N F CV A + + N ++ R +GN+CY + + + V++
Sbjct: 342 VAGKETTNIFSNCGCVRAE--GDISNVANGFKSHLI----RLIGNLCYKNKDNQDKVNEL 395
Query: 132 GGAQIVIDHLRSLCSITD--PANEKLLTVFCGMLMNYSNENDSLQAQLINMGVI-PTLVK 188
G +++D+ C+I+D P + + L +++N L A++ G+ +L+K
Sbjct: 396 DGIPLILDN----CNISDSNPFLTQWVIYAIRNLTEDNSQNQDLIAKMEEQGLADASLLK 451
Query: 189 LLGIHCQ 195
+G +
Sbjct: 452 KVGFEVE 458
>gi|4504901 karyopherin alpha 4 [Homo sapiens]
Length = 521
Score = 35.4 bits (80), Expect = 0.15
Identities = 83/382 (21%), Positives = 147/382 (38%), Gaps = 51/382 (13%)
Query: 35 LAQNNTETSEKIQASGILQLFASLLTPQS--SCKAKVANIIAEVAKNEFMRIPCVDAGLI 92
L+ + + + SGIL + L S + + A + +A + V
Sbjct: 99 LSSDRNPPIDDLIKSGILPILVHCLERDDNPSLQFEAAWALTNIASGTSEQTQAVVQSNA 158
Query: 93 SPL-VQLLNSKDQEVLLQTGRALGNICYDSHEGRSAVDQAG---------GAQIVIDHLR 142
PL ++LL+S Q V Q ALGNI D + R V G I I LR
Sbjct: 159 VPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFISPSIPITFLR 218
Query: 143 S-------LCSITDPAN-----EKLLTVFCGML--------------MNYSNENDSLQAQ 176
+ LC DP +++L C ++ ++Y + + Q Q
Sbjct: 219 NVTWVMVNLCRHKDPPPPMETIQEILPALCVLIHHTDVNILVDTVWALSYLTDAGNEQIQ 278
Query: 177 L-INMGVIPTLVKLLGIHCQNAALTEMCLVAFGNLAELESSKEQFA-STNIAEELVKLFK 234
+ I+ G++P LV LL Q + L A GN+ + Q + + L
Sbjct: 279 MVIDSGIVPHLVPLLS--HQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLT 336
Query: 235 KQIEHDKREMIFEVLAPLAENDAIKLQLVEAGLVECLLEIVQQKVDSDKEDDITELKTGS 294
E +E ++ + A N +++A LV ++ ++ DK D T+ +
Sbjct: 337 HPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMIIHLL------DKGDFGTQKEAAW 390
Query: 295 DLMVLLLLG-DESMQKLFEGGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARNDANCI- 352
+ L + G + + L + F +L+ + Q+ L G I A ++A I
Sbjct: 391 AISNLTISGRKDQVAYLIQQNVIPPFCNLLTVKDAQVVQVVLDGLSNILKMAEDEAETIG 450
Query: 353 HMVDN-GIVEKLMDLLDRHVED 373
++++ G +EK+ L + ED
Sbjct: 451 NLIEECGGLEKIEQLQNHENED 472
>gi|222144293 karyopherin alpha 1 [Homo sapiens]
Length = 538
Score = 33.9 bits (76), Expect = 0.45
Identities = 26/104 (25%), Positives = 45/104 (43%), Gaps = 7/104 (6%)
Query: 87 VDAGLISPLVQLLNSKDQEVLLQTGRALGNICYDSHEGRSAVDQAGGAQIVIDHLRSLCS 146
+DAG+ LV+LL D +V+ RA+GNI + D + L+SL
Sbjct: 293 IDAGVCRRLVELLMHNDYKVVSPALRAVGNIV-------TGDDIQTQVILNCSALQSLLH 345
Query: 147 ITDPANEKLLTVFCGMLMNYSNENDSLQAQLINMGVIPTLVKLL 190
+ E + C + N + N + +I+ + P L+ +L
Sbjct: 346 LLSSPKESIKKEACWTISNITAGNRAQIQTVIDANIFPALISIL 389
>gi|146231975 catenin, delta 1 isoform 3A [Homo sapiens]
Length = 832
Score = 33.9 bits (76), Expect = 0.45
Identities = 31/118 (26%), Positives = 54/118 (45%), Gaps = 10/118 (8%)
Query: 163 LMNYSNENDSLQAQLINMGVIPTLVKLLGIHCQNAALTEMCLVAFGNLAELESSKEQFAS 222
L + ND ++ + + IP LV LL + E+ L A G L + ++Q
Sbjct: 289 LQHLCYRNDKVKTDVRKLKGIPVLVGLL-----DHPKKEVHLGACGALKNISFGRDQDNK 343
Query: 223 TNIAE-----ELVKLFKKQIEHDKREMIFEVLAPLAENDAIKLQLVEAGLVECLLEIV 275
I LV+L +K + D E+I L L+ +D+IK+++V+ L E++
Sbjct: 344 IAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVI 401
>gi|146231948 catenin, delta 1 isoform 3A [Homo sapiens]
Length = 832
Score = 33.9 bits (76), Expect = 0.45
Identities = 31/118 (26%), Positives = 54/118 (45%), Gaps = 10/118 (8%)
Query: 163 LMNYSNENDSLQAQLINMGVIPTLVKLLGIHCQNAALTEMCLVAFGNLAELESSKEQFAS 222
L + ND ++ + + IP LV LL + E+ L A G L + ++Q
Sbjct: 289 LQHLCYRNDKVKTDVRKLKGIPVLVGLL-----DHPKKEVHLGACGALKNISFGRDQDNK 343
Query: 223 TNIAE-----ELVKLFKKQIEHDKREMIFEVLAPLAENDAIKLQLVEAGLVECLLEIV 275
I LV+L +K + D E+I L L+ +D+IK+++V+ L E++
Sbjct: 344 IAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVI 401
>gi|146231994 catenin, delta 1 isoform 3A [Homo sapiens]
Length = 832
Score = 33.9 bits (76), Expect = 0.45
Identities = 31/118 (26%), Positives = 54/118 (45%), Gaps = 10/118 (8%)
Query: 163 LMNYSNENDSLQAQLINMGVIPTLVKLLGIHCQNAALTEMCLVAFGNLAELESSKEQFAS 222
L + ND ++ + + IP LV LL + E+ L A G L + ++Q
Sbjct: 289 LQHLCYRNDKVKTDVRKLKGIPVLVGLL-----DHPKKEVHLGACGALKNISFGRDQDNK 343
Query: 223 TNIAE-----ELVKLFKKQIEHDKREMIFEVLAPLAENDAIKLQLVEAGLVECLLEIV 275
I LV+L +K + D E+I L L+ +D+IK+++V+ L E++
Sbjct: 344 IAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVI 401
>gi|146231977 catenin, delta 1 isoform 3AC [Homo sapiens]
Length = 838
Score = 33.9 bits (76), Expect = 0.45
Identities = 31/118 (26%), Positives = 54/118 (45%), Gaps = 10/118 (8%)
Query: 163 LMNYSNENDSLQAQLINMGVIPTLVKLLGIHCQNAALTEMCLVAFGNLAELESSKEQFAS 222
L + ND ++ + + IP LV LL + E+ L A G L + ++Q
Sbjct: 289 LQHLCYRNDKVKTDVRKLKGIPVLVGLL-----DHPKKEVHLGACGALKNISFGRDQDNK 343
Query: 223 TNIAE-----ELVKLFKKQIEHDKREMIFEVLAPLAENDAIKLQLVEAGLVECLLEIV 275
I LV+L +K + D E+I L L+ +D+IK+++V+ L E++
Sbjct: 344 IAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVI 401
>gi|146231946 catenin, delta 1 isoform 3B [Homo sapiens]
Length = 840
Score = 33.9 bits (76), Expect = 0.45
Identities = 31/118 (26%), Positives = 54/118 (45%), Gaps = 10/118 (8%)
Query: 163 LMNYSNENDSLQAQLINMGVIPTLVKLLGIHCQNAALTEMCLVAFGNLAELESSKEQFAS 222
L + ND ++ + + IP LV LL + E+ L A G L + ++Q
Sbjct: 289 LQHLCYRNDKVKTDVRKLKGIPVLVGLL-----DHPKKEVHLGACGALKNISFGRDQDNK 343
Query: 223 TNIAE-----ELVKLFKKQIEHDKREMIFEVLAPLAENDAIKLQLVEAGLVECLLEIV 275
I LV+L +K + D E+I L L+ +D+IK+++V+ L E++
Sbjct: 344 IAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVI 401
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.132 0.359
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,622,944
Number of Sequences: 37866
Number of extensions: 712265
Number of successful extensions: 2267
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 58
Number of HSP's that attempted gapping in prelim test: 2119
Number of HSP's gapped (non-prelim): 130
length of query: 608
length of database: 18,247,518
effective HSP length: 108
effective length of query: 500
effective length of database: 14,157,990
effective search space: 7078995000
effective search space used: 7078995000
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.