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Search of human proteins with 154759423
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|154759423 Cdk5 and Abl enzyme substrate 1 isoform 2 [Homo
sapiens]
(633 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|154759423 Cdk5 and Abl enzyme substrate 1 isoform 2 [Homo sap... 1266 0.0
gi|24308408 Cdk5 and Abl enzyme substrate 1 isoform 1 [Homo sapi... 700 0.0
gi|145275195 Cdk5 and Abl enzyme substrate 2 [Homo sapiens] 434 e-121
gi|165905613 ring finger and KH domain containing 1 [Homo sapiens] 56 9e-08
gi|7706469 Kruppel-like factor [Homo sapiens] 54 6e-07
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] 53 1e-06
gi|110832843 TBP-associated factor 4 [Homo sapiens] 52 2e-06
gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap... 52 2e-06
gi|126090909 engrailed homeobox 1 [Homo sapiens] 50 5e-06
gi|59806361 hypothetical protein LOC387104 [Homo sapiens] 50 5e-06
gi|4504713 insulinoma-associated 1 [Homo sapiens] 50 8e-06
gi|55750053 atrophin-1 [Homo sapiens] 49 1e-05
gi|55750041 atrophin-1 [Homo sapiens] 49 1e-05
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 49 1e-05
gi|122937321 UNC homeobox [Homo sapiens] 49 1e-05
gi|42544130 splicing factor 1 isoform 1 [Homo sapiens] 49 2e-05
gi|239757043 PREDICTED: functional smad suppressing element 18 [... 48 2e-05
gi|239751555 PREDICTED: functional smad suppressing element 18 [... 48 2e-05
gi|239746067 PREDICTED: functional smad suppressing element 18 [... 48 2e-05
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ... 48 2e-05
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ... 48 2e-05
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ... 48 2e-05
gi|154146199 sal-like 3 [Homo sapiens] 48 3e-05
gi|142976757 immediate early response 5 [Homo sapiens] 47 7e-05
gi|118766337 zinc finger protein of the cerebellum 5 [Homo sapiens] 46 9e-05
gi|156071470 hyperpolarization activated cyclic nucleotide-gated... 46 1e-04
gi|12707580 paired-like homeobox 2b [Homo sapiens] 46 1e-04
gi|57222568 myeloid/lymphoid or mixed-lineage leukemia (trithora... 46 1e-04
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 46 1e-04
gi|42519916 forkhead box O3A [Homo sapiens] 45 2e-04
>gi|154759423 Cdk5 and Abl enzyme substrate 1 isoform 2 [Homo
sapiens]
Length = 633
Score = 1266 bits (3276), Expect = 0.0
Identities = 633/633 (100%), Positives = 633/633 (100%)
Query: 1 MAAAAAAATTAACSSGSAGTDAAGASGLQQPPPQPQPQPAAAAPAQPPPEPPRKPRMDPR 60
MAAAAAAATTAACSSGSAGTDAAGASGLQQPPPQPQPQPAAAAPAQPPPEPPRKPRMDPR
Sbjct: 1 MAAAAAAATTAACSSGSAGTDAAGASGLQQPPPQPQPQPAAAAPAQPPPEPPRKPRMDPR 60
Query: 61 RRQAALSFLTNISLDGRLPPQDAEWGGGEEGGAAKPGAGGACGARTRFSLLAAAERGGCI 120
RRQAALSFLTNISLDGRLPPQDAEWGGGEEGGAAKPGAGGACGARTRFSLLAAAERGGCI
Sbjct: 61 RRQAALSFLTNISLDGRLPPQDAEWGGGEEGGAAKPGAGGACGARTRFSLLAAAERGGCI 120
Query: 121 ALAAPGTPAAGLAAGSGPCLPQPSSLPPLIPGGHATVSGPGVARGFASPLGAGRASGEQW 180
ALAAPGTPAAGLAAGSGPCLPQPSSLPPLIPGGHATVSGPGVARGFASPLGAGRASGEQW
Sbjct: 121 ALAAPGTPAAGLAAGSGPCLPQPSSLPPLIPGGHATVSGPGVARGFASPLGAGRASGEQW 180
Query: 181 QPPRPAPLAACAQLQLLDGSGAAGQEELEEDDAFISVQVPAAAFLGSGTPGSGSGSRGRL 240
QPPRPAPLAACAQLQLLDGSGAAGQEELEEDDAFISVQVPAAAFLGSGTPGSGSGSRGRL
Sbjct: 181 QPPRPAPLAACAQLQLLDGSGAAGQEELEEDDAFISVQVPAAAFLGSGTPGSGSGSRGRL 240
Query: 241 NSFTQGILPIAFSRPTSQNYCSLEQPGQGGSTSAFEQLQRSRRRLISQRSSLETLEDIEE 300
NSFTQGILPIAFSRPTSQNYCSLEQPGQGGSTSAFEQLQRSRRRLISQRSSLETLEDIEE
Sbjct: 241 NSFTQGILPIAFSRPTSQNYCSLEQPGQGGSTSAFEQLQRSRRRLISQRSSLETLEDIEE 300
Query: 301 NAPLRRCRTLSGSPRPKNFKKIHFIKNMRQHDTRNGRIVLISGRRSFCSIFSVLPYRDST 360
NAPLRRCRTLSGSPRPKNFKKIHFIKNMRQHDTRNGRIVLISGRRSFCSIFSVLPYRDST
Sbjct: 301 NAPLRRCRTLSGSPRPKNFKKIHFIKNMRQHDTRNGRIVLISGRRSFCSIFSVLPYRDST 360
Query: 361 QVGDLKLDGGRQSTGAVSLKEIIGLEGVELGADGKTVSYTQFLLPTNAFGARRNTIDSTS 420
QVGDLKLDGGRQSTGAVSLKEIIGLEGVELGADGKTVSYTQFLLPTNAFGARRNTIDSTS
Sbjct: 361 QVGDLKLDGGRQSTGAVSLKEIIGLEGVELGADGKTVSYTQFLLPTNAFGARRNTIDSTS 420
Query: 421 SFSQFRNLSHRSLSIGRASGTQGSLDTGSDLGDFMDYDPNLLDDPQWPCGKHKRVLIFPS 480
SFSQFRNLSHRSLSIGRASGTQGSLDTGSDLGDFMDYDPNLLDDPQWPCGKHKRVLIFPS
Sbjct: 421 SFSQFRNLSHRSLSIGRASGTQGSLDTGSDLGDFMDYDPNLLDDPQWPCGKHKRVLIFPS 480
Query: 481 YMTTVIDYVKPSDLKKDMNETFKEKFPHIKLTLSKIRSLKREMRKLAQEDCGLEEPTVAM 540
YMTTVIDYVKPSDLKKDMNETFKEKFPHIKLTLSKIRSLKREMRKLAQEDCGLEEPTVAM
Sbjct: 481 YMTTVIDYVKPSDLKKDMNETFKEKFPHIKLTLSKIRSLKREMRKLAQEDCGLEEPTVAM 540
Query: 541 AFVYFEKLALKGKLNKQNRKLCAGACVLLAAKIGSDLKKHEVKHLIDKLEEKFRLNRREL 600
AFVYFEKLALKGKLNKQNRKLCAGACVLLAAKIGSDLKKHEVKHLIDKLEEKFRLNRREL
Sbjct: 541 AFVYFEKLALKGKLNKQNRKLCAGACVLLAAKIGSDLKKHEVKHLIDKLEEKFRLNRREL 600
Query: 601 IAFEFPVLVALEFALHLPEHEVMPHYRRLVQSS 633
IAFEFPVLVALEFALHLPEHEVMPHYRRLVQSS
Sbjct: 601 IAFEFPVLVALEFALHLPEHEVMPHYRRLVQSS 633
>gi|24308408 Cdk5 and Abl enzyme substrate 1 isoform 1 [Homo
sapiens]
Length = 368
Score = 700 bits (1806), Expect = 0.0
Identities = 351/351 (100%), Positives = 351/351 (100%)
Query: 283 RRLISQRSSLETLEDIEENAPLRRCRTLSGSPRPKNFKKIHFIKNMRQHDTRNGRIVLIS 342
RRLISQRSSLETLEDIEENAPLRRCRTLSGSPRPKNFKKIHFIKNMRQHDTRNGRIVLIS
Sbjct: 18 RRLISQRSSLETLEDIEENAPLRRCRTLSGSPRPKNFKKIHFIKNMRQHDTRNGRIVLIS 77
Query: 343 GRRSFCSIFSVLPYRDSTQVGDLKLDGGRQSTGAVSLKEIIGLEGVELGADGKTVSYTQF 402
GRRSFCSIFSVLPYRDSTQVGDLKLDGGRQSTGAVSLKEIIGLEGVELGADGKTVSYTQF
Sbjct: 78 GRRSFCSIFSVLPYRDSTQVGDLKLDGGRQSTGAVSLKEIIGLEGVELGADGKTVSYTQF 137
Query: 403 LLPTNAFGARRNTIDSTSSFSQFRNLSHRSLSIGRASGTQGSLDTGSDLGDFMDYDPNLL 462
LLPTNAFGARRNTIDSTSSFSQFRNLSHRSLSIGRASGTQGSLDTGSDLGDFMDYDPNLL
Sbjct: 138 LLPTNAFGARRNTIDSTSSFSQFRNLSHRSLSIGRASGTQGSLDTGSDLGDFMDYDPNLL 197
Query: 463 DDPQWPCGKHKRVLIFPSYMTTVIDYVKPSDLKKDMNETFKEKFPHIKLTLSKIRSLKRE 522
DDPQWPCGKHKRVLIFPSYMTTVIDYVKPSDLKKDMNETFKEKFPHIKLTLSKIRSLKRE
Sbjct: 198 DDPQWPCGKHKRVLIFPSYMTTVIDYVKPSDLKKDMNETFKEKFPHIKLTLSKIRSLKRE 257
Query: 523 MRKLAQEDCGLEEPTVAMAFVYFEKLALKGKLNKQNRKLCAGACVLLAAKIGSDLKKHEV 582
MRKLAQEDCGLEEPTVAMAFVYFEKLALKGKLNKQNRKLCAGACVLLAAKIGSDLKKHEV
Sbjct: 258 MRKLAQEDCGLEEPTVAMAFVYFEKLALKGKLNKQNRKLCAGACVLLAAKIGSDLKKHEV 317
Query: 583 KHLIDKLEEKFRLNRRELIAFEFPVLVALEFALHLPEHEVMPHYRRLVQSS 633
KHLIDKLEEKFRLNRRELIAFEFPVLVALEFALHLPEHEVMPHYRRLVQSS
Sbjct: 318 KHLIDKLEEKFRLNRRELIAFEFPVLVALEFALHLPEHEVMPHYRRLVQSS 368
>gi|145275195 Cdk5 and Abl enzyme substrate 2 [Homo sapiens]
Length = 478
Score = 434 bits (1116), Expect = e-121
Identities = 231/362 (63%), Positives = 271/362 (74%), Gaps = 12/362 (3%)
Query: 279 QRSRRRLISQRSSLETLEDIEENAPLRRCRTLSGSPRPKNFKKIHFIKNMRQHDTRNGRI 338
QR R+R+ SQR SLE LED AP +R + SGSPR K KK HFIKNMRQ+DTRN RI
Sbjct: 118 QRQRKRVTSQRCSLEFLEDAVGCAPAQRTKHTSGSPRHKGLKKTHFIKNMRQYDTRNSRI 177
Query: 339 VLISGRRSFCSIFSVLPYRDSTQVGDLKLDGGRQS--TGAVSLKE--IIGLEGVELGADG 394
VLI +RS C+ FSVLPY + ++ DL++D +Q +G VS+ + LEGVELGADG
Sbjct: 178 VLICAKRSLCAAFSVLPYGEGLRISDLRVDSQKQRHPSGGVSVSSEMVFELEGVELGADG 237
Query: 395 KTVSYTQFLLPTNAFGARRNTIDSTSSFSQFRNLSHRSLSIGR-----ASGTQGSLDTGS 449
K VSY +FL PTNA ++ DS R R+L R S + GS
Sbjct: 238 KVVSYAKFLYPTNALVTHKS--DSHGLLPTPRPSVPRTLPGSRHKPAPTKSAPASTELGS 295
Query: 450 DLGDFMDYDPNLLDDPQWPCGKHKRVLIFPSYMTTVIDYVKPSDLKKDMNETFKEKFPHI 509
D+GD ++Y+PNLLDDPQWPCGKHKRVLIF SYMTTVI+YVKPSDLKKDMNETF+EKFPH+
Sbjct: 296 DVGDTLEYNPNLLDDPQWPCGKHKRVLIFASYMTTVIEYVKPSDLKKDMNETFREKFPHV 355
Query: 510 KLTLSKIRSLKREMRKLAQEDCGLEEPTVAMAFVYFEKLALKGKLNKQNRKLCAGACVLL 569
KLTLSKIRSLKREMR L++E C LE TVAMA+VYFEKL L+GKL+KQNRKLCAGACVLL
Sbjct: 356 KLTLSKIRSLKREMRSLSEE-CSLEPVTVAMAYVYFEKLVLQGKLSKQNRKLCAGACVLL 414
Query: 570 AAKIGSDLKKHEVKHLIDKLEEKFRLNRRELIAFEFPVLVALEFALHLPEHEVMPHYRRL 629
AAKI SDL+K V LIDKLEE+FR NRR+LI FEF VLVALE AL+LPE++V+PHYRRL
Sbjct: 415 AAKISSDLRKSGVTQLIDKLEERFRFNRRDLIGFEFTVLVALELALYLPENQVLPHYRRL 474
Query: 630 VQ 631
Q
Sbjct: 475 TQ 476
Score = 55.1 bits (131), Expect = 2e-07
Identities = 34/61 (55%), Positives = 37/61 (60%), Gaps = 4/61 (6%)
Query: 22 AAGASGLQQPPPQPQPQPAAAAP---AQPPPEPPRKPRMDPRRRQAALSFLTNISLDGRL 78
AA A G P P P P AAP A+ PP+ R+ R D RRRQAAL FL NISLDGR
Sbjct: 3 AAAAGGAPGPAPGPAGPPPPAAPTSAARAPPQALRR-RGDSRRRQAALFFLNNISLDGRP 61
Query: 79 P 79
P
Sbjct: 62 P 62
Score = 32.7 bits (73), Expect = 1.0
Identities = 22/59 (37%), Positives = 27/59 (45%), Gaps = 10/59 (16%)
Query: 24 GASGLQQPPPQPQPQPAAAAPAQPPPEPP-----RKPRMDPRRRQAALSFLTNISLDGR 77
G G + PPP P A PA PPPEPP R P P+ + T + LDG+
Sbjct: 65 GPGGEKPPPP---PAEAREPPAPPPPEPPTGLPARTPA--PQGLLSPTQVPTGLGLDGQ 118
>gi|165905613 ring finger and KH domain containing 1 [Homo sapiens]
Length = 651
Score = 56.2 bits (134), Expect = 9e-08
Identities = 52/152 (34%), Positives = 62/152 (40%), Gaps = 14/152 (9%)
Query: 16 GSAGTDAAGASGLQQPPPQPQPQPAAAAPAQPPPEPPRKPRMDPRRRQAALSFLTNISLD 75
G G GA+G + P P P P P A A P P PP +P + AL L+ + L
Sbjct: 14 GGGGGGGVGAAG-EDPGPGPAPPPEGAQEAAPAPRPPPEPDDAAAALRLALDQLSALGLG 72
Query: 76 GRLPPQDAEWGGGEEGGAAKPGAGGACGARTRFSLLAAAERGGCIALAAPGTPAAGLAAG 135
G G +E GAA GA A GA + G AP T A +A G
Sbjct: 73 GA--------GDTDEEGAAGDGAAAAGGADGGAAPEPVPPDGP--EAGAPPTLAPAVAPG 122
Query: 136 SGPCLPQPSSLPPLIPGGHATVSGPGVARGFA 167
S P L +S PP P S P V GFA
Sbjct: 123 SLPLLDPNASPPPPPP---PRPSPPDVFAGFA 151
Score = 33.9 bits (76), Expect = 0.47
Identities = 34/112 (30%), Positives = 45/112 (40%), Gaps = 13/112 (11%)
Query: 118 GCIAL-AAPGTPAAGLAAGSGPCLPQPSSLPPLIPGGHATVSGPGVARGFASPLGAGRAS 176
GC + APG PAAG SG P+ S P L G + P RG P+GA
Sbjct: 487 GCSTVNGAPGPPAAGARRSSGAGTPRHS--PTLPEPGGLRLELPLSRRGAPDPVGA---- 540
Query: 177 GEQWQPPR-----PAPLAACAQLQLLDGSGAAGQEELEEDDAFISVQVPAAA 223
W+PP+ P A L AA L+ + S + P+A+
Sbjct: 541 -LSWRPPQGPVSFPGGAAFSTATSLPSSPAAAACAPLDSGASENSRKPPSAS 591
Score = 32.7 bits (73), Expect = 1.0
Identities = 21/73 (28%), Positives = 25/73 (34%), Gaps = 18/73 (24%)
Query: 1 MAAAAAAATTAACSSGSAGTDAAGASGLQQPPPQPQPQPAAAAP---------------- 44
+ A T ++G A GA G P P P P A AP
Sbjct: 69 LGLGGAGDTDEEGAAGDGAAAAGGADGGAAPEPVPPDGPEAGAPPTLAPAVAPGSLPLLD 128
Query: 45 --AQPPPEPPRKP 55
A PPP PP +P
Sbjct: 129 PNASPPPPPPPRP 141
>gi|7706469 Kruppel-like factor [Homo sapiens]
Length = 355
Score = 53.5 bits (127), Expect = 6e-07
Identities = 56/180 (31%), Positives = 63/180 (35%), Gaps = 24/180 (13%)
Query: 17 SAGTDAAGASGLQQPPPQPQPQPAA--AAPAQPPPEPPRKPRMDPRRRQAALSFLTNISL 74
S G D GA +PPP P P PA P PPP + + L +L
Sbjct: 50 SMGLDGLGAEAAPEPPPPPPP-PAFYYPEPGAPPPYSAPAGGLVSELLRPELDAPLGPAL 108
Query: 75 DGRL---PPQDAEWGGGEEGGAAKPGAGGACGARTRFSLLAAAERG--GCIALAAPGTPA 129
GR PP G A P A G G + RG G APG PA
Sbjct: 109 HGRFLLAPP-------GRLVKAEPPEADGGGG----YGCAPGLTRGPRGLKREGAPG-PA 156
Query: 130 AGLAAGSGPCLPQPSSLPPLIPGGHATVSGPGVARGFASPLG----AGRASGEQWQPPRP 185
A G G P P PPL P G A + PG F P G G + PP P
Sbjct: 157 ASCMRGPGGRPPPPPDTPPLSPDGPARLPAPGPRASFPPPFGGPGFGAPGPGLHYAPPAP 216
>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
Length = 538
Score = 52.8 bits (125), Expect = 1e-06
Identities = 55/174 (31%), Positives = 65/174 (37%), Gaps = 45/174 (25%)
Query: 4 AAAAATTAACSSGSA--GTDAAGASGLQQPPPQPQPQPAAAAPA-------------QPP 48
AAAAA TA S G A G A A+ L PPP P PA A PA +PP
Sbjct: 151 AAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPP 210
Query: 49 PEPPRKPRMDPRRRQAALSFLTNISLDGRLPPQ---DAEWGGGEEGGAAKP--------- 96
PP +P P+++Q PPQ E G GGAA+P
Sbjct: 211 LPPPPQPPAPPQQQQPP-------------PPQPQPPPEGGAVRAGGAARPVSLREVVRY 257
Query: 97 --GAGGACGARTRFSLLAAAERGGCIALAAPGTPAAGLAAGSGPCLPQPSSLPP 148
G+GGA G TR + E T LA G +P PP
Sbjct: 258 LGGSGGAGGRLTRGRVQGLLEEEAAARGRLERTRLGALALPRG---DRPGRAPP 308
Score = 36.6 bits (83), Expect = 0.072
Identities = 59/224 (26%), Positives = 75/224 (33%), Gaps = 63/224 (28%)
Query: 31 PPPQPQPQPAAAAPAQPPPEPPRKPRMDPRRRQAALSFLTNISLDGRLPPQDAEWGGGEE 90
PP P+ PAAAA A PPP P P P A + PP
Sbjct: 111 PPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSP-------- 162
Query: 91 GGAAKPGAGGACGARTRFSLLAAAERGGCIALAAPGTPAA--GLAAGSGPCLPQPSSL-- 146
G A+PG A+R +A A P PAA +A +GP P ++
Sbjct: 163 -GPAQPG--------------PRAQRAAPLA-APPPAPAAPPAVAPPAGPRRAPPPAVAA 206
Query: 147 --PPLIPGGHATVSGPGVARGFASPLGAGRASGEQWQPPRPAPLAACAQLQLLDGSGAAG 204
PPL P A +Q QPP P P + + GAA
Sbjct: 207 REPPLPPPPQPP------------------APPQQQQPPPPQPQPP-PEGGAVRAGGAAR 247
Query: 205 QEELEEDDAFISVQVPAAAFLGSGTPGSGSGSRGRLNSFTQGIL 248
L E +LG G +RGR+ QG+L
Sbjct: 248 PVSLRE----------VVRYLGGSGGAGGRLTRGRV----QGLL 277
Score = 34.3 bits (77), Expect = 0.36
Identities = 25/70 (35%), Positives = 30/70 (42%), Gaps = 12/70 (17%)
Query: 8 ATTAACSSGSAGTDAAGASGLQQPPPQPQPQP---AAAAPAQPP---------PEPPRKP 55
AT A G AA A+ P P P P P AAAAPA+ P P P
Sbjct: 106 ATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPA 165
Query: 56 RMDPRRRQAA 65
+ PR ++AA
Sbjct: 166 QPGPRAQRAA 175
Score = 32.7 bits (73), Expect = 1.0
Identities = 31/100 (31%), Positives = 40/100 (40%), Gaps = 30/100 (30%)
Query: 74 LDGRLPPQDA-----EWG------GGEEGGAAKPGAGGACGARTRFSLLAAAERGGCIAL 122
L+G PQ A EW G +EG PG+G R FS+ A + GG ++
Sbjct: 364 LNGERGPQSAKERVKEWTPCGPHQGQDEGRGPAPGSG----TRQVFSMAAMNKEGGTASV 419
Query: 123 AAPGTPAAGLAAGSGPCLPQPSSLP---PLIPGGHATVSG 159
A +GP P P LP P +PG T G
Sbjct: 420 A------------TGPDSPSPVPLPPGKPALPGADGTPFG 447
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 52.0 bits (123), Expect = 2e-06
Identities = 58/213 (27%), Positives = 75/213 (35%), Gaps = 28/213 (13%)
Query: 2 AAAAAAATTAACSSGSAGTDAAGASG--------LQQPPPQPQPQPAAAAPAQPPPEPPR 53
AAAA A S AG AG + +PPP + +P P +P P PR
Sbjct: 52 AAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPR 111
Query: 54 KPRMDPRRRQAALSFLTNISLDGRLPPQDAEWGGGEEGGAAKPGAGGACGARTRFSLLAA 113
+P + A R PP+ G G A A A A +
Sbjct: 112 RPLVPAGPAPPAAKL--------RPPPE------GSAGSCAPVPAAAAVAAGPEPAPAGP 157
Query: 114 AERGGCIALAAPGTPAAGLAAGSGPCLPQPSSLPPLIPGGHATVSGPGV---ARGFASPL 170
A+ G ALAA P G G G P P P PG T++G + A+P
Sbjct: 158 AKPAGPAALAARAGPGPGPGPGPG---PGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPA 214
Query: 171 GAGRASGEQWQPPRPAPLAACAQLQLLDGSGAA 203
+ +G P P P A +Q GAA
Sbjct: 215 VSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAA 247
Score = 52.0 bits (123), Expect = 2e-06
Identities = 55/179 (30%), Positives = 62/179 (34%), Gaps = 47/179 (26%)
Query: 6 AAATTAACSSGSAGTDAAGASGLQQPPPQPQPQPAAAAPAQPPP------EPPRKPRMDP 59
AA T + G A A PP P P AAAP PPP PP P P
Sbjct: 232 AAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPP 291
Query: 60 RRRQAALSFLTNISLDGRLPPQDAEWGGGEEGGAAKPG--AGGACGARTRFSLLAAA--- 114
A +PP A GG G A P AGG G + AAA
Sbjct: 292 TAAPA-------------VPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAP 338
Query: 115 ------ERGGCIALAAPGTPAAGLAAGSGPC---------------LPQPSSLPPLIPG 152
E + AAP PAA A SGP LP P+++PP PG
Sbjct: 339 APGVKAESPKRVVQAAP--PAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPG 395
Score = 45.1 bits (105), Expect = 2e-04
Identities = 73/266 (27%), Positives = 94/266 (35%), Gaps = 33/266 (12%)
Query: 3 AAAAAATTAACSSGSAGTDAAGASGLQQPPPQPQPQPAAAAPAQPPPEPPRKPRMDPRRR 62
+A + A A ++ +AG + A A P +P A AA A P P P P P
Sbjct: 133 SAGSCAPVPAAAAVAAGPEPAPAG-----PAKPAGPAALAARAGPGPGPGPGPGPGPGPG 187
Query: 63 QAALSFLTNISLDGRLPPQDAEWGGG------EEGGAA-----KPGAGGACGARTRFSLL 111
+ A +L+G ++ G AA KP A G F
Sbjct: 188 KPAGPGAAQ-TLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGA 246
Query: 112 AAAERGGCIALAAPGTPAAGLAAGSGPCLPQPSSLPPLI--PGGHATVSGPGVARGFASP 169
AA A AAP PAA A P P P + P GH +GP A P
Sbjct: 247 AAPP-----APAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHP--AGPPTAAPAVPP 299
Query: 170 LGAGRASGEQWQPPRPAPLA-ACAQLQLLDGSGAAGQE-----ELEEDDAFISVQVPAAA 223
A + G P PAP A A + G GAA + E + PAA
Sbjct: 300 PAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQ 359
Query: 224 FLGSGTPGSGSGSRGRLNSFTQGILP 249
L + P S + S + QG LP
Sbjct: 360 TLAASGPASTAASM-VIGPTMQGALP 384
>gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens]
Length = 2161
Score = 52.0 bits (123), Expect = 2e-06
Identities = 71/224 (31%), Positives = 90/224 (40%), Gaps = 34/224 (15%)
Query: 4 AAAAATTAACSSGSAGTDAAGASGLQQPPPQPQPQPAAAAPA--QPPPEPPRKPRMDP-- 59
+ A++ T+ S + T A A+ PP P P PAA APA QP P+PP P D
Sbjct: 1619 STASSLTSYDSEVATLTQGASAAPGDPHPPGP-PAPAAPAPAAPQPGPDPP--PGTDSGI 1675
Query: 60 ---RRRQAALSFLTNISLDGRLPPQDAEWGGGEEGGAAKPGAGGACGARTRFSLLAAAER 116
R ++ L IS L AE GGG GG GAG A G + +A +
Sbjct: 1676 EEVDSRSSSDHPLETISSASTLSSLSAE-GGGSAGGGGGAGAGVASGPELLDTYVAYLDG 1734
Query: 117 GGCIALAAPGTP----------AAGLAAG-SGPCLPQPSS--LPPLIP-GGHATVSGPG- 161
+ PG P G A G SG P PS P+ P +V+G G
Sbjct: 1735 QAFGGSSTPGPPYPPQLMTPSKLRGRALGASGGLRPGPSGGLRDPVTPTSPTVSVTGAGT 1794
Query: 162 ----VARGFASPLGAGRASG----EQWQPPRPAPLAACAQLQLL 197
R + P AG A G E PP P P A+ +LL
Sbjct: 1795 DGLLALRACSGPPTAGVAGGPVAVEPEVPPVPLPTASSLPRKLL 1838
Score = 38.9 bits (89), Expect = 0.015
Identities = 59/206 (28%), Positives = 76/206 (36%), Gaps = 43/206 (20%)
Query: 12 ACSSGSAGTDAAGASGLQQPPPQPQP---------QPAAAAPAQP-PPEPPRKPRMDPRR 61
A S+ S+G + G+S +PP QP+P P+ A P PP P P
Sbjct: 1162 APSTSSSGRSSQGSSTEAEPPTQPEPTGGGGGGGSSPSPAPAMSPVPPSPSPVPTPASPS 1221
Query: 62 RQAALSFLTNI--SLDGRLPPQDAEW---------------GGGEEGGAAKPGAGGACGA 104
A L F + +L G ++ W G E+GG G G A G
Sbjct: 1222 GPATLDFTSQFGAALVG-AARREGGWQNEARRRSTLFLSTDAGDEDGGDGGLGTGAAPGP 1280
Query: 105 RTRFSL-----LAAAERGGCIALAAPGTPAAGLAAGS------GPCLPQPSSLPPLIPGG 153
R R S + +AE + A G G AGS G S LPP P
Sbjct: 1281 RLRHSKSIDEGMFSAEPYLRLESAGSGAGYGGYGAGSRAYGGGGGSSAFTSFLPPR-PLV 1339
Query: 154 HATVSGPGVARGFASPLGAGRASGEQ 179
H G A ASPLG A+ E+
Sbjct: 1340 HPLT---GKALDPASPLGLALAARER 1362
Score = 32.3 bits (72), Expect = 1.4
Identities = 61/233 (26%), Positives = 77/233 (33%), Gaps = 53/233 (22%)
Query: 26 SGLQQPPPQPQPQPAAAAPAQPPPEPPRKPRMDPRRRQAALSFLTNISLDGRLPPQDAEW 85
S L PP P P A A PP PP P A S L D+E
Sbjct: 1582 SPLTPGPPHPLPDTPAPATPLPPVPPPAVAAAPPTLDSTASS----------LTSYDSEV 1631
Query: 86 GGGEEGGAAKPGAGGACGARTRFSLLAAAERGGCIALAAPGTPAAGLAAGSGPCLPQPSS 145
+G +A PG G + AA + G P G +G + SS
Sbjct: 1632 ATLTQGASAAPGDPHPPGPPAPAAPAPAAPQPG-------PDPPPGTDSGIEEVDSRSSS 1684
Query: 146 LPPLIPGGHATVSGPGVARGFASPLGAGRASGEQWQPPRPAPLAACAQLQLLDGSG-AAG 204
PL A+ A G S G G A G+G A+G
Sbjct: 1685 DHPLETISSASTLSSLSAEGGGSAGGGGGA-----------------------GAGVASG 1721
Query: 205 QEELEEDDAFISVQVPAAAFLGSGTPG--------SGSGSRGRLNSFTQGILP 249
E L+ A++ Q AF GS TPG + S RGR + G+ P
Sbjct: 1722 PELLDTYVAYLDGQ----AFGGSSTPGPPYPPQLMTPSKLRGRALGASGGLRP 1770
Score = 32.0 bits (71), Expect = 1.8
Identities = 68/279 (24%), Positives = 92/279 (32%), Gaps = 55/279 (19%)
Query: 4 AAAAATTAACSSGSAGTDAAGASG--LQQPPPQPQPQPAAAAPAQPPPEPPRKPRMDPRR 61
AA+AA SG G G ++Q + +PQ P P P P P+ P
Sbjct: 1091 AASAAMYVPARSGR------GRKGPLVKQTKVEGEPQKGGGLPPAPSPTSPASPQPPP-- 1142
Query: 62 RQAALSFLTNISLDGRLPPQDAEWGGGEEGGAAKPGAGGACGARTRFSLLAAAERGGCIA 121
AA S +I +P + G + G+ T+ GG
Sbjct: 1143 AVAAPSEKNSIP----IPTIIIKAPSTSSSGRSSQGSSTEAEPPTQPEPTGGGGGGGSSP 1198
Query: 122 LAAPGTPAAGLAAGSGPCLPQPSSLP-PLIPGGHATVSGPGVARGFASPLGAG------R 174
AP P P PS +P P P G AT+ F S GA R
Sbjct: 1199 SPAP---------AMSPVPPSPSPVPTPASPSGPATLD-------FTSQFGAALVGAARR 1242
Query: 175 ASGEQWQPPRPAPLAACAQLQLLD------GSGAAGQEELEEDDAFISVQVPAAAFL--- 225
G Q + R + L D G+GAA L + A +L
Sbjct: 1243 EGGWQNEARRRSTLFLSTDAGDEDGGDGGLGTGAAPGPRLRHSKSIDEGMFSAEPYLRLE 1302
Query: 226 ----GSGTPGSGSGSR-----GRLNSFTQGILPIAFSRP 255
G+G G G+GSR G ++FT + P P
Sbjct: 1303 SAGSGAGYGGYGAGSRAYGGGGGSSAFTSFLPPRPLVHP 1341
Score = 30.8 bits (68), Expect = 4.0
Identities = 35/120 (29%), Positives = 42/120 (35%), Gaps = 22/120 (18%)
Query: 120 IALAAPGTPAAGLAAGSGPCLPQPSSLPPLIPGGHATVSGPGVARGFASPLGAGRASGEQ 179
+ +APG AA SG P S P T G R +SP GA S +
Sbjct: 449 MVFSAPG------AASSGAPGPTSGSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSR 502
Query: 180 WQPPRPAPLAACAQLQLLDGSGAAGQEELEEDDAFISVQVPAAAFLGSGTPGSGSGSRGR 239
+ P A Q + S +E PA GSG PG GSRGR
Sbjct: 503 GRHPEDAK----RQPRGRPSSSGTPREG------------PAGGTGGSGGPGGSLGSRGR 546
Score = 30.0 bits (66), Expect = 6.8
Identities = 21/60 (35%), Positives = 25/60 (41%), Gaps = 6/60 (10%)
Query: 2 AAAAAAATTAACSSGSAGT-DAAGASGLQQPP-----PQPQPQPAAAAPAQPPPEPPRKP 55
AAAA AT+ + SS S T G +PP P P PA+ P P P P
Sbjct: 1962 AAAAPGATSPSASSSSTSTRHLQGVEFEMRPPLLRRAPSPSLLPASEHKVSPAPRPSSLP 2021
>gi|126090909 engrailed homeobox 1 [Homo sapiens]
Length = 392
Score = 50.4 bits (119), Expect = 5e-06
Identities = 60/210 (28%), Positives = 80/210 (38%), Gaps = 33/210 (15%)
Query: 2 AAAAAAATT-----AACSSGSAGTDAAGASGLQQP-PPQPQPQPAAAAPA---------- 45
A AAAA T + S G++G+ +G+ G P PQP P AAP
Sbjct: 15 ALGAAAAATPGGLSLSLSPGASGSSGSGSDGDSVPVSPQPAPPSPPAAPCLPPLAHHPHL 74
Query: 46 --QPPPEPPRKPRMDPRRRQ--AALSFLTNISLDGRLPPQDAEWGGGEE--------GGA 93
PPP PP+ + Q A L TN +D L P ++G +E A
Sbjct: 75 PPHPPPPPPQHLAAPAHQPQPAAQLHRTTNFFIDNILRP---DFGCKKEQPPPQLLVAAA 131
Query: 94 AKPGAGGACGA-RTRFSLLAAAERGGCIALAAPGTPAAGLAAGSGPCLPQPSSLPPLIPG 152
A+ GAGG R R A + + APG A+ L A C P S P
Sbjct: 132 ARGGAGGGGRVERDRGQTAAGRDPVHPLGTRAPGA-ASLLCAPDANCGPPDGSQPAAAGA 190
Query: 153 GHATVSGPGVARGFASPLGAGRASGEQWQP 182
G + P A A+ A A+ +P
Sbjct: 191 GASKAGNPAAAAAAAAAAVAAAAAAAAAKP 220
Score = 29.6 bits (65), Expect = 8.8
Identities = 28/87 (32%), Positives = 32/87 (36%), Gaps = 12/87 (13%)
Query: 19 GTDAAGASGLQQPP-----PQPQPQPAAAAPAQPPPEPPRKPRMDPRRRQAALSFLTNIS 73
GT A GA+ L P P QPAAA P AA + + +
Sbjct: 160 GTRAPGAASLLCAPDANCGPPDGSQPAAAGAGASKAGNPAAAAA------AAAAAVAAAA 213
Query: 74 LDGRLPPQDAEWGGGEEGGAAKPGAGG 100
P D GGG GGA PGA G
Sbjct: 214 AAAAAKPSDTG-GGGSGGGAGSPGAQG 239
>gi|59806361 hypothetical protein LOC387104 [Homo sapiens]
Length = 947
Score = 50.4 bits (119), Expect = 5e-06
Identities = 77/264 (29%), Positives = 95/264 (35%), Gaps = 55/264 (20%)
Query: 11 AACSSGSAGTDAA-------GASGLQQPPPQPQPQPAA--AAPAQPPPEPPRKPRMDPRR 61
A+ G G + A A G QP + PAA AA P PP +P PR
Sbjct: 93 ASIRGGGGGAEKATPLAPKGAAPGAVQPVAGAEAAPAATLAALGGRRPGPPEEP---PRE 149
Query: 62 RQAALSFLTNISLDGRLPPQDAEWGGGEEGGAAKPGAGGACGARTRFSLLAAAERGGCIA 121
++ S L G PP GGG EGG GAGG G R + RG
Sbjct: 150 LESVPSKL------GEPPPLGEGGGGGGEGG----GAGGGSGEREGGAPQPPPPRG---- 195
Query: 122 LAAPGTPA--AGLAAGSGPCLPQPSSLPPLIPGGHATVSGPGVARGFASPLGAGRASGEQ 179
G A G + G G SS PG + SG GVA G G+G G
Sbjct: 196 WRGKGVRAQQRGGSGGEGASPSPSSSSAGKTPGTGSRNSGSGVAGG-----GSG-GGGSY 249
Query: 180 W--------------QPPRPAPLAACAQLQLLDGSGA-------AGQEELEEDDAFISVQ 218
W + R A AA AQ+ +G G+ +G + E A S
Sbjct: 250 WKEGCLQSELIQFHLKKERAAAAAAAAQMHAKNGGGSSSRSSPVSGPPAVCETLAVASAS 309
Query: 219 VPAAAFLGSGTPGSGSGSRGRLNS 242
AAA G GS S G + +
Sbjct: 310 PMAAAAEGPQQSAEGSASGGGMQA 333
Score = 32.0 bits (71), Expect = 1.8
Identities = 44/182 (24%), Positives = 62/182 (34%), Gaps = 14/182 (7%)
Query: 28 LQQPP-PQPQPQPAAAAPAQPPPEPPRKPRMDPRRRQAALSFLTNISLDGRLPPQDAEWG 86
+ QPP P AAA+PA E P R++Q A S P+D+
Sbjct: 1 MSQPPIGGAAPATAAASPAAAATEARLHPEGSSRKQQRAQS---------PARPRDSSLR 51
Query: 87 GGEEGGAAKPGAGGACGARTRFSLLAAAERGGCIALAAPGTPAAGLAAGSGPCLPQPSSL 146
+ GAG + + L ++G + G PA+ G G P +
Sbjct: 52 QTIAATRSPVGAGTKLNSVRQQQLQQQQQQGNKTG-SRTGPPASIRGGGGGAEKATPLAP 110
Query: 147 PPLIPGGHATVSGPGVARGFASPLGAGRASGEQWQPPR---PAPLAACAQLQLLDGSGAA 203
PG V+G A GR G +PPR P L +G G
Sbjct: 111 KGAAPGAVQPVAGAEAAPAATLAALGGRRPGPPEEPPRELESVPSKLGEPPPLGEGGGGG 170
Query: 204 GQ 205
G+
Sbjct: 171 GE 172
>gi|4504713 insulinoma-associated 1 [Homo sapiens]
Length = 510
Score = 49.7 bits (117), Expect = 8e-06
Identities = 47/153 (30%), Positives = 61/153 (39%), Gaps = 24/153 (15%)
Query: 3 AAAAAATTAACSSGSAGTDAAGASGLQQPPPQP-------QPQPAAAAPAQPPPEPPRKP 55
A AA A AC+ G QPPPQ P+ A AP P P +
Sbjct: 62 AHAALAAALACAPGP------------QPPPQGPRAAHFGNPEAAHPAPLYSPTRPVSRE 109
Query: 56 RMDPRRRQAALSFLTNISLDGRLPPQDAEWGGGEEGGAAKPGAGGACGARTRFSLLAAAE 115
+ + + + + +S + P A GGG GGA+ G GG CG L A AE
Sbjct: 110 HEKHKYFERSFNLGSPVSAES-FPTPAALLGGGGGGGASGAGGGGTCGGDP--LLFAPAE 166
Query: 116 RGGCIALAAPGTPAAGLAAGSGPCLPQPSSLPP 148
A +A A G G GP LP ++L P
Sbjct: 167 LKMGTAFSAGAEAARG--PGPGPPLPPAAALRP 197
Score = 36.2 bits (82), Expect = 0.095
Identities = 51/192 (26%), Positives = 66/192 (34%), Gaps = 32/192 (16%)
Query: 1 MAAAAAAATTAACSSGSAGTDAAGASGLQQPPPQPQPQPAAAAPAQPPPEPPRKPRMDPR 60
M A +A AA G G A+ L+ P +P P AA PA+ P K R
Sbjct: 169 MGTAFSAGAEAARGPGP-GPPLPPAAALRPPGKRPPPPTAAEPPAKAVKAPGAKKPKAIR 227
Query: 61 RRQAALSFLTNISLDGRLPPQDAEWGGGEEGGAAKPGAGGACGARTRFSLLAAAERGGCI 120
+ T+ L ++ E G GGAA+P C L E
Sbjct: 228 KLHFEDEVTTSPVLGLKIKEGPVEAPRGRAGGAARPLGEFIC-------QLCKEEYADPF 280
Query: 121 ALAAPGTPAAGLAAGSGPCLPQPSSLPPLIPGGHATVSGPGVARGFASPLGAGRASGEQW 180
ALA + + C P A+ F+ P A AS +W
Sbjct: 281 ALAQ--HKCSRIVRVEYRC--------------------PECAKVFSCP--ANLASHRRW 316
Query: 181 QPPRPAPLAACA 192
PRPAP AA A
Sbjct: 317 HKPRPAPAAARA 328
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 49.3 bits (116), Expect = 1e-05
Identities = 64/261 (24%), Positives = 88/261 (33%), Gaps = 40/261 (15%)
Query: 14 SSGSAGTDAAGASGLQQ-------PPP--QPQPQPAAAAPAQPPPEPPRKPRMDPRRRQA 64
S GS D+ +SGL Q PPP P PQP + P QP P + P A
Sbjct: 137 SPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHA 196
Query: 65 ALSFLTNISLD---GRLPPQDAEWGG-----------GEEGGAAKPGAGGACGARTRFSL 110
+ T+ G PP + G G +GG A GG G +
Sbjct: 197 PMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPP 256
Query: 111 LAAAERGGCIALAAPGT--PAAGLAAGSGPCLPQPSSLPPLIPG----------GHATVS 158
A AP T P + G+ P P P++ P + P +A+ S
Sbjct: 257 TTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASAS 316
Query: 159 GPGVAR-----GFASPLGAGRASGEQWQPPRPAPLAACAQLQLLDGSGAAGQEELEEDDA 213
PG+ SP G+ G P P A + L S +A + +
Sbjct: 317 PPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYS 376
Query: 214 FISVQVPAAAFLGSGTPGSGS 234
S AA+ S + S S
Sbjct: 377 SSSSSSAAASSSSSSSSSSAS 397
Score = 30.8 bits (68), Expect = 4.0
Identities = 44/156 (28%), Positives = 51/156 (32%), Gaps = 16/156 (10%)
Query: 14 SSGSAGTDAAGASGLQQPPPQPQPQPAAAAPAQPPPEPPRKPRMDPRRRQAALSFLTNIS 73
SS S+ + + G+ P P PQ AP PP P A +
Sbjct: 571 SSNSSSSTSQGSYPCSHPSPSQGPQ---GAPYPFPPVPTVTTSSATLSTVIATVASSPAG 627
Query: 74 LDGRLPPQDAEWGGGEEGGAAKPGA-------GGACGARTRFSLLAAAERGGCIALAAPG 126
PP +G A PGA G G+ F G A PG
Sbjct: 628 YKTASPPGPPPYGKR----APSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPG 683
Query: 127 TPAAGL-AAGSGPCLPQ-PSSLPPLIPGGHATVSGP 160
T G G GP P PS LP L P A SGP
Sbjct: 684 TFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGP 719
>gi|55750041 atrophin-1 [Homo sapiens]
Length = 1190
Score = 49.3 bits (116), Expect = 1e-05
Identities = 64/261 (24%), Positives = 88/261 (33%), Gaps = 40/261 (15%)
Query: 14 SSGSAGTDAAGASGLQQ-------PPP--QPQPQPAAAAPAQPPPEPPRKPRMDPRRRQA 64
S GS D+ +SGL Q PPP P PQP + P QP P + P A
Sbjct: 137 SPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHA 196
Query: 65 ALSFLTNISLD---GRLPPQDAEWGG-----------GEEGGAAKPGAGGACGARTRFSL 110
+ T+ G PP + G G +GG A GG G +
Sbjct: 197 PMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPP 256
Query: 111 LAAAERGGCIALAAPGT--PAAGLAAGSGPCLPQPSSLPPLIPG----------GHATVS 158
A AP T P + G+ P P P++ P + P +A+ S
Sbjct: 257 TTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASAS 316
Query: 159 GPGVAR-----GFASPLGAGRASGEQWQPPRPAPLAACAQLQLLDGSGAAGQEELEEDDA 213
PG+ SP G+ G P P A + L S +A + +
Sbjct: 317 PPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYS 376
Query: 214 FISVQVPAAAFLGSGTPGSGS 234
S AA+ S + S S
Sbjct: 377 SSSSSSAAASSSSSSSSSSAS 397
Score = 30.8 bits (68), Expect = 4.0
Identities = 44/156 (28%), Positives = 51/156 (32%), Gaps = 16/156 (10%)
Query: 14 SSGSAGTDAAGASGLQQPPPQPQPQPAAAAPAQPPPEPPRKPRMDPRRRQAALSFLTNIS 73
SS S+ + + G+ P P PQ AP PP P A +
Sbjct: 571 SSNSSSSTSQGSYPCSHPSPSQGPQ---GAPYPFPPVPTVTTSSATLSTVIATVASSPAG 627
Query: 74 LDGRLPPQDAEWGGGEEGGAAKPGA-------GGACGARTRFSLLAAAERGGCIALAAPG 126
PP +G A PGA G G+ F G A PG
Sbjct: 628 YKTASPPGPPPYGKR----APSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPG 683
Query: 127 TPAAGL-AAGSGPCLPQ-PSSLPPLIPGGHATVSGP 160
T G G GP P PS LP L P A SGP
Sbjct: 684 TFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGP 719
>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
sapiens]
Length = 483
Score = 48.9 bits (115), Expect = 1e-05
Identities = 51/171 (29%), Positives = 67/171 (39%), Gaps = 25/171 (14%)
Query: 31 PPPQPQPQPAAAAPAQPPPEPP-------RKPRMDPRRRQAALSFLTN-------ISLDG 76
PPP P P P AP PPP P R DP+ R A L+ + ++
Sbjct: 8 PPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLRKVTQIND 67
Query: 77 RLPPQ-DAEWGGGEEGGAAKPGAGGACGARTRFSLLAAAERGGCIALAAPGTPAAGLAAG 135
R PQ ++ G +EGG G+ GA T +L G + A AG G
Sbjct: 68 RSAPQIESSKGTNKEGG----GSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAGGKTG 123
Query: 136 SGPCLPQPSSLPPLIPGGHATVSGPGVARGFASPLGAGRASG-EQWQPPRP 185
GP PS P +P + T+SGP + A G + PPRP
Sbjct: 124 QGPGSRAPS---PRLP--NKTISGPLIPPASPRLGNTSEAHGAARTAPPRP 169
Score = 32.0 bits (71), Expect = 1.8
Identities = 48/183 (26%), Positives = 61/183 (33%), Gaps = 20/183 (10%)
Query: 31 PPPQPQPQPAAAAPAQPPPEPPRKPRMDPRRRQAALSFLTNISLDGRLPPQDAEWGGGEE 90
PPP P P PPP PP P +A L + L PP G
Sbjct: 223 PPPPPPP---------PPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYP 273
Query: 91 GGAAKPGAGGACGARTRFSLLAAAERGGC---IALAAPGTPAAGLAAGSGPCLPQPS--- 144
G A+P + C +L AP P ++ + P LP S
Sbjct: 274 GLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSF 333
Query: 145 SLPPLIPGGHATVSGPGV--ARGFASPLGAGR--ASGEQWQPPRPAPLAACAQLQLLDGS 200
PP G A + P ++ F GR A G + PP PAP A +L S
Sbjct: 334 QAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPP-PAPPARSPTTELSSKS 392
Query: 201 GAA 203
A
Sbjct: 393 QQA 395
Score = 30.4 bits (67), Expect = 5.2
Identities = 14/40 (35%), Positives = 17/40 (42%)
Query: 20 TDAAGASGLQQPPPQPQPQPAAAAPAQPPPEPPRKPRMDP 59
++A GA+ P P P P PPP PP P P
Sbjct: 156 SEAHGAARTAPPRPNVPAPPPPTPPPPPPPLPPPLPSSSP 195
>gi|122937321 UNC homeobox [Homo sapiens]
Length = 531
Score = 48.9 bits (115), Expect = 1e-05
Identities = 74/238 (31%), Positives = 89/238 (37%), Gaps = 32/238 (13%)
Query: 14 SSGSAGTDAAGASGLQQPPPQPQPQPAAAAPA-----------QPPPEPPRKPRMDPRRR 62
S+ S+ +D+ G GL PP+P P PAA P PP EPP DP
Sbjct: 229 SAPSSDSDSGGG-GLSPEPPEP-PPPAAKGPGAHASGAAGTAPAPPGEPPAPGTCDPAFY 286
Query: 63 QAALSFLTNISLDGRLPPQD-AEWGGGEEGGAAKPGAGGACGAR--TRFSLLAAAERGGC 119
+ S GR +D A G G A + GA G A + SLL+ +
Sbjct: 287 PSQRSGAGPQPRPGRPADKDAASCGPGAAVAAVERGAAGLPKASPFSVESLLSDSPPRRK 346
Query: 120 IALAAPGTPAAGLAAGSG-PCLPQPSSLPPLIPGGHATVSGPGVARGFASPL-----GAG 173
A A AAGL G PC P+ LI GH + GF P GAG
Sbjct: 347 AASNAAAAAAAGLDFAPGLPCAPR-----TLIGKGHFLLYPITQPLGFLVPQAALKGGAG 401
Query: 174 RASGEQWQPPRPA-PLAACAQLQLLDGSGAAGQEELEEDDAFISVQVPAAAFLGSGTP 230
+ PP PA P A AQ SG G D AF A A G+ P
Sbjct: 402 LEPAPKDAPPAPAVPPAPPAQASFGAFSGPGG----APDSAFARRSPDAVASPGAPAP 455
Score = 33.9 bits (76), Expect = 0.47
Identities = 17/44 (38%), Positives = 21/44 (47%), Gaps = 1/44 (2%)
Query: 8 ATTAACSSGSAGTDAAGASGLQQPPPQPQPQPAAAAPAQPPPEP 51
A+ AA G AG +G PPP P P+P P+ P EP
Sbjct: 464 ASAAATEGGGGDCADAGTAGPAPPPPAPSPRPGPRPPS-PAEEP 506
Score = 30.0 bits (66), Expect = 6.8
Identities = 17/46 (36%), Positives = 20/46 (43%), Gaps = 4/46 (8%)
Query: 10 TAACSSGSAGTDAAGASGLQQPPPQPQPQPAAAAPAQPPPEPPRKP 55
+AA + G G D A A PP P P P P PP P +P
Sbjct: 465 SAAATEGGGG-DCADAGTAGPAPPPPAPSP---RPGPRPPSPAEEP 506
>gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
Length = 639
Score = 48.5 bits (114), Expect = 2e-05
Identities = 52/175 (29%), Positives = 62/175 (35%), Gaps = 27/175 (15%)
Query: 27 GLQQPPPQP---QPQPAAAAPA--------QPPPEPPRKPRM---DPRRRQAALSFLTNI 72
G+ PPP P QP P + P QPPP PP M P Q + T
Sbjct: 476 GMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTS 535
Query: 73 SLDGRLPPQDAEWGGGEEGGAAKPGAGGACGARTRFSLLAAAERGGCIALAAPGTPAAGL 132
+ G +PP W + AA PGA G T L + P P
Sbjct: 536 AGTGSIPP----WQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPG 591
Query: 133 AAGSGPCLPQPSSLPPLIPGGHATVSGPGVARGFASPLGAGRASGEQWQPPRPAP 187
+AG P P PP+ P T+ G GVA P G A PP P P
Sbjct: 592 SAGM-MYAPPPPPPPPMDPSNFVTMMGMGVAG--MPPFGMPPA------PPPPPP 637
Score = 35.0 bits (79), Expect = 0.21
Identities = 24/62 (38%), Positives = 27/62 (43%), Gaps = 7/62 (11%)
Query: 4 AAAAATTAACSSGSAGTDAAGASGLQQP------PPQPQPQPAAAAPAQPPPEPPRKPRM 57
AAAAA+ A T G+Q P PP P P P +A PP PP P M
Sbjct: 549 AAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMYAPPPPP-PPPM 607
Query: 58 DP 59
DP
Sbjct: 608 DP 609
>gi|239757043 PREDICTED: functional smad suppressing element 18
[Homo sapiens]
Length = 996
Score = 48.1 bits (113), Expect = 2e-05
Identities = 47/146 (32%), Positives = 55/146 (37%), Gaps = 22/146 (15%)
Query: 2 AAAAAAATTAACSSGSAGTDAAGASGLQQPPPQPQPQPAAAAPAQPPPEPPRKPRM---D 58
AAA AAA A G G GA PPP P P P A A P ++PR D
Sbjct: 261 AAAVAAAAAVAGGGGLLGPHLLGA-----PPPPPPPPPPLAELAGAPHAHHKRPRFDDDD 315
Query: 59 PRRRQAALSFLTNISLDGRLPPQDAEWGGGEEGGAAKPGAGGACGARTRFSLLAAAERGG 118
++AA+ ++S A GG GG GAGG C A G
Sbjct: 316 DSLQEAAVVAAASLSAAAASLSVAAASGGAGTGGG---GAGGGCVAGV-----------G 361
Query: 119 CIALAAPGTPAAGLAAGSGPCLPQPS 144
A A G A S P +P PS
Sbjct: 362 VGAGAGAGAGAGAKGPRSYPVIPVPS 387
Score = 38.5 bits (88), Expect = 0.019
Identities = 52/188 (27%), Positives = 60/188 (31%), Gaps = 35/188 (18%)
Query: 2 AAAAAAATTAACSSGSAGTDAAGASGLQQP---------------PPQPQPQPAAAAPAQ 46
A AAA A A + G+ AG SGL P PP+ Q
Sbjct: 427 AGAAAEALGGAGAGGAGAAPKAGLSGLFWPAGRKDAFYPPFCMFWPPRTPGGLPVPTYLQ 486
Query: 47 PPPEPPRK-----PRMDPRRRQAALSFLTNISLDGRL-----PPQDAEWGGGEEGGAAKP 96
PPP+PP RQA L G P Q + G P
Sbjct: 487 PPPQPPSALGCALGESPALLRQAFLDLAEPGGAAGSAEAAPPPGQPPQVVANGPGSGPPP 546
Query: 97 GAGGACGARTRFSLLAAAERGGCIALAAP------GTPAAGLAAGSGPC---LPQPSSLP 147
AGGA F G C A + P A AAGSGP +P P P
Sbjct: 547 PAGGAGSRDALFESPPGGSGGDCSAGSTPPADSVAAAGAGAAAAGSGPAGSRVPAPHH-P 605
Query: 148 PLIPGGHA 155
L+ G A
Sbjct: 606 HLLEGRKA 613
Score = 30.0 bits (66), Expect = 6.8
Identities = 29/98 (29%), Positives = 35/98 (35%), Gaps = 2/98 (2%)
Query: 22 AAGASGLQQPPPQPQPQPAAAAPAQPPPEPPRKPRMDPRRRQAALSFLTNISLDGRLPPQ 81
AAG++ PP QP PQ A P PP P ++ G PP
Sbjct: 519 AAGSAEAAPPPGQP-PQVVANGPGSGPPPPAGGAGSRDALFESPPGGSGGDCSAGSTPPA 577
Query: 82 DAEWGGGEEGGAAKPG-AGGACGARTRFSLLAAAERGG 118
D+ G AA G AG A LL + GG
Sbjct: 578 DSVAAAGAGAAAAGSGPAGSRVPAPHHPHLLEGRKAGG 615
Score = 29.6 bits (65), Expect = 8.8
Identities = 34/116 (29%), Positives = 43/116 (37%), Gaps = 26/116 (22%)
Query: 140 LPQPSSLP---PLIPGGHATVSGPGVARGFASPLGAGRASGEQWQPPRPAPLAACAQLQL 196
LPQP + P PL A V+ G LG PP P PLA A
Sbjct: 244 LPQPGAHPACHPLSSVKAAAVAAAAAVAGGGGLLGPHLLGAPPPPPPPPPPLAELA---- 299
Query: 197 LDGSGAAGQEEL---EEDDAFISVQVPAAAFL--------------GSGTPGSGSG 235
G+ A + ++DD+ V AAA L G+GT G G+G
Sbjct: 300 --GAPHAHHKRPRFDDDDDSLQEAAVVAAASLSAAAASLSVAAASGGAGTGGGGAG 353
>gi|239751555 PREDICTED: functional smad suppressing element 18
[Homo sapiens]
Length = 1252
Score = 48.1 bits (113), Expect = 2e-05
Identities = 47/146 (32%), Positives = 55/146 (37%), Gaps = 22/146 (15%)
Query: 2 AAAAAAATTAACSSGSAGTDAAGASGLQQPPPQPQPQPAAAAPAQPPPEPPRKPRM---D 58
AAA AAA A G G GA PPP P P P A A P ++PR D
Sbjct: 261 AAAVAAAAAVAGGGGLLGPHLLGA-----PPPPPPPPPPLAELAGAPHAHHKRPRFDDDD 315
Query: 59 PRRRQAALSFLTNISLDGRLPPQDAEWGGGEEGGAAKPGAGGACGARTRFSLLAAAERGG 118
++AA+ ++S A GG GG GAGG C A G
Sbjct: 316 DSLQEAAVVAAASLSAAAASLSVAAASGGAGTGGG---GAGGGCVAGV-----------G 361
Query: 119 CIALAAPGTPAAGLAAGSGPCLPQPS 144
A A G A S P +P PS
Sbjct: 362 VGAGAGAGAGAGAKGPRSYPVIPVPS 387
Score = 38.5 bits (88), Expect = 0.019
Identities = 52/188 (27%), Positives = 60/188 (31%), Gaps = 35/188 (18%)
Query: 2 AAAAAAATTAACSSGSAGTDAAGASGLQQP---------------PPQPQPQPAAAAPAQ 46
A AAA A A + G+ AG SGL P PP+ Q
Sbjct: 427 AGAAAEALGGAGAGGAGAAPKAGLSGLFWPAGRKDAFYPPFCMFWPPRTPGGLPVPTYLQ 486
Query: 47 PPPEPPRK-----PRMDPRRRQAALSFLTNISLDGRL-----PPQDAEWGGGEEGGAAKP 96
PPP+PP RQA L G P Q + G P
Sbjct: 487 PPPQPPSALGCALGESPALLRQAFLDLAEPGGAAGSAEAAPPPGQPPQVVANGPGSGPPP 546
Query: 97 GAGGACGARTRFSLLAAAERGGCIALAAP------GTPAAGLAAGSGPC---LPQPSSLP 147
AGGA F G C A + P A AAGSGP +P P P
Sbjct: 547 PAGGAGSRDALFESPPGGSGGDCSAGSTPPADSVAAAGAGAAAAGSGPAGSRVPAPHH-P 605
Query: 148 PLIPGGHA 155
L+ G A
Sbjct: 606 HLLEGRKA 613
Score = 30.0 bits (66), Expect = 6.8
Identities = 29/98 (29%), Positives = 35/98 (35%), Gaps = 2/98 (2%)
Query: 22 AAGASGLQQPPPQPQPQPAAAAPAQPPPEPPRKPRMDPRRRQAALSFLTNISLDGRLPPQ 81
AAG++ PP QP PQ A P PP P ++ G PP
Sbjct: 519 AAGSAEAAPPPGQP-PQVVANGPGSGPPPPAGGAGSRDALFESPPGGSGGDCSAGSTPPA 577
Query: 82 DAEWGGGEEGGAAKPG-AGGACGARTRFSLLAAAERGG 118
D+ G AA G AG A LL + GG
Sbjct: 578 DSVAAAGAGAAAAGSGPAGSRVPAPHHPHLLEGRKAGG 615
Score = 29.6 bits (65), Expect = 8.8
Identities = 34/116 (29%), Positives = 43/116 (37%), Gaps = 26/116 (22%)
Query: 140 LPQPSSLP---PLIPGGHATVSGPGVARGFASPLGAGRASGEQWQPPRPAPLAACAQLQL 196
LPQP + P PL A V+ G LG PP P PLA A
Sbjct: 244 LPQPGAHPACHPLSSVKAAAVAAAAAVAGGGGLLGPHLLGAPPPPPPPPPPLAELA---- 299
Query: 197 LDGSGAAGQEEL---EEDDAFISVQVPAAAFL--------------GSGTPGSGSG 235
G+ A + ++DD+ V AAA L G+GT G G+G
Sbjct: 300 --GAPHAHHKRPRFDDDDDSLQEAAVVAAASLSAAAASLSVAAASGGAGTGGGGAG 353
>gi|239746067 PREDICTED: functional smad suppressing element 18
[Homo sapiens]
Length = 1252
Score = 48.1 bits (113), Expect = 2e-05
Identities = 47/146 (32%), Positives = 55/146 (37%), Gaps = 22/146 (15%)
Query: 2 AAAAAAATTAACSSGSAGTDAAGASGLQQPPPQPQPQPAAAAPAQPPPEPPRKPRM---D 58
AAA AAA A G G GA PPP P P P A A P ++PR D
Sbjct: 261 AAAVAAAAAVAGGGGLLGPHLLGA-----PPPPPPPPPPLAELAGAPHAHHKRPRFDDDD 315
Query: 59 PRRRQAALSFLTNISLDGRLPPQDAEWGGGEEGGAAKPGAGGACGARTRFSLLAAAERGG 118
++AA+ ++S A GG GG GAGG C A G
Sbjct: 316 DSLQEAAVVAAASLSAAAASLSVAAASGGAGTGGG---GAGGGCVAGV-----------G 361
Query: 119 CIALAAPGTPAAGLAAGSGPCLPQPS 144
A A G A S P +P PS
Sbjct: 362 VGAGAGAGAGAGAKGPRSYPVIPVPS 387
Score = 38.5 bits (88), Expect = 0.019
Identities = 52/188 (27%), Positives = 60/188 (31%), Gaps = 35/188 (18%)
Query: 2 AAAAAAATTAACSSGSAGTDAAGASGLQQP---------------PPQPQPQPAAAAPAQ 46
A AAA A A + G+ AG SGL P PP+ Q
Sbjct: 427 AGAAAEALGGAGAGGAGAAPKAGLSGLFWPAGRKDAFYPPFCMFWPPRTPGGLPVPTYLQ 486
Query: 47 PPPEPPRK-----PRMDPRRRQAALSFLTNISLDGRL-----PPQDAEWGGGEEGGAAKP 96
PPP+PP RQA L G P Q + G P
Sbjct: 487 PPPQPPSALGCALGESPALLRQAFLDLAEPGGAAGSAEAAPPPGQPPQVVANGPGSGPPP 546
Query: 97 GAGGACGARTRFSLLAAAERGGCIALAAP------GTPAAGLAAGSGPC---LPQPSSLP 147
AGGA F G C A + P A AAGSGP +P P P
Sbjct: 547 PAGGAGSRDALFESPPGGSGGDCSAGSTPPADSVAAAGAGAAAAGSGPAGSRVPAPHH-P 605
Query: 148 PLIPGGHA 155
L+ G A
Sbjct: 606 HLLEGRKA 613
Score = 30.0 bits (66), Expect = 6.8
Identities = 29/98 (29%), Positives = 35/98 (35%), Gaps = 2/98 (2%)
Query: 22 AAGASGLQQPPPQPQPQPAAAAPAQPPPEPPRKPRMDPRRRQAALSFLTNISLDGRLPPQ 81
AAG++ PP QP PQ A P PP P ++ G PP
Sbjct: 519 AAGSAEAAPPPGQP-PQVVANGPGSGPPPPAGGAGSRDALFESPPGGSGGDCSAGSTPPA 577
Query: 82 DAEWGGGEEGGAAKPG-AGGACGARTRFSLLAAAERGG 118
D+ G AA G AG A LL + GG
Sbjct: 578 DSVAAAGAGAAAAGSGPAGSRVPAPHHPHLLEGRKAGG 615
Score = 29.6 bits (65), Expect = 8.8
Identities = 34/116 (29%), Positives = 43/116 (37%), Gaps = 26/116 (22%)
Query: 140 LPQPSSLP---PLIPGGHATVSGPGVARGFASPLGAGRASGEQWQPPRPAPLAACAQLQL 196
LPQP + P PL A V+ G LG PP P PLA A
Sbjct: 244 LPQPGAHPACHPLSSVKAAAVAAAAAVAGGGGLLGPHLLGAPPPPPPPPPPLAELA---- 299
Query: 197 LDGSGAAGQEEL---EEDDAFISVQVPAAAFL--------------GSGTPGSGSG 235
G+ A + ++DD+ V AAA L G+GT G G+G
Sbjct: 300 --GAPHAHHKRPRFDDDDDSLQEAAVVAAASLSAAAASLSVAAASGGAGTGGGGAG 353
>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo
sapiens]
Length = 1650
Score = 48.1 bits (113), Expect = 2e-05
Identities = 51/197 (25%), Positives = 74/197 (37%), Gaps = 9/197 (4%)
Query: 15 SGSAGTDAAGASGLQQPPPQPQPQPAAAAPAQPPPEPPRKPRMD--PRRRQAALSFLTNI 72
SGS G G G++ P + + + P +P P P+ P D P+ + F +
Sbjct: 1132 SGSPGIQ--GEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDP 1189
Query: 73 SLDGRLPP--QDAEWGG-GEEGGAAKPGAGGACGARTRFSLLAAAERGGCIALAAPGTPA 129
G P QD G GE+G +PG+ G G L +RG + + G
Sbjct: 1190 GPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLG--KRGPAGSPGSEGRQG 1247
Query: 130 AGLAAGSGPCLPQPSSLPPLIPGGHATVSGPGVARGFASPLGAGRASGEQWQPPRPAPLA 189
A G + P P+ P G A GP RG +G G Q P P+
Sbjct: 1248 GKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVG 1307
Query: 190 ACAQLQLLDGSGAAGQE 206
L +GA G++
Sbjct: 1308 PPGLPGLRGDAGAKGEK 1324
Score = 37.4 bits (85), Expect = 0.042
Identities = 50/176 (28%), Positives = 61/176 (34%), Gaps = 20/176 (11%)
Query: 16 GSAG-TDAAGASGLQQPPPQPQ----PQPAAAAPAQPPPEPPRKPRMDPRRRQAALSFLT 70
G+AG T G G PP P P A + P PP P D + L
Sbjct: 845 GAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKD------GPAGLR 898
Query: 71 NISLDGRLPPQDAEWG-GGEEGGAAKPGAGGACGARTRFSLLAAAERGGCIALAAPGTPA 129
+ LP G G EG + PG G+ G R AA GG I PG P
Sbjct: 899 GFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGER------GAAGSGGPIG--PPGRPG 950
Query: 130 AGLAAGSGPCLPQPSSLPPLIPGGHATVSGPGVARGFASPLGAGRASGEQWQPPRP 185
G+ P P+ P G V GP G A P G G++ + P
Sbjct: 951 PQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDP 1006
Score = 36.6 bits (83), Expect = 0.072
Identities = 56/193 (29%), Positives = 67/193 (34%), Gaps = 25/193 (12%)
Query: 11 AACSSGSAGTDAAGASGLQQPPPQ---PQPQPAAAAPA-QPPPEPPRK---PRMDPRRRQ 63
A SG+ GT +G G PP + P PQ P + PP PP K P +R +
Sbjct: 768 ATGKSGAKGT--SGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGE 825
Query: 64 AALSFLTNI-SLDGRLPPQDAEWGGGEEGGAAKPGAGGACGARTRFSLLAAAERGGCIAL 122
T G + PQ A G G PG G G + L A + G
Sbjct: 826 VGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQ---GLPGTAGKEG--TK 880
Query: 123 AAPGTPAAGLAAGSGPC----LPQPSSLPPLIPG----GHATVSGPGVARGFASPLGAGR 174
PG P G GP P LP G G+ SGP G GA
Sbjct: 881 GDPGPP--GAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAG 938
Query: 175 ASGEQWQPPRPAP 187
+ G P RP P
Sbjct: 939 SGGPIGPPGRPGP 951
Score = 35.8 bits (81), Expect = 0.12
Identities = 57/251 (22%), Positives = 77/251 (30%), Gaps = 37/251 (14%)
Query: 15 SGSAGTDAAGASGLQQPPPQPQPQPAAAAPAQPPPEPPRKPRMDPRRRQAALSFLTNISL 74
+GS G++ + P P P P P KP D R L
Sbjct: 1237 AGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAG-PAGKPGPDGLR-----------GL 1284
Query: 75 DGRLPPQDAEWGGGEEGGAAKPGAGGACGARTRFSLLAAAERGGCIALAAP--------- 125
G + Q G+ G G G G R G I L P
Sbjct: 1285 PGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGD 1344
Query: 126 -GTPAAGLAAGSGPCLPQPSSLPPLIPGGHATVSGPGVARGFASPLGAGRASGE---QWQ 181
G P + G + P + P+ PGG + GP +G G G GE Q
Sbjct: 1345 RGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGP 1404
Query: 182 PPRPAPLAAC-----AQLQLLDGSGAAGQEELEEDDAFISVQVPAAAFLGSGTPGSGSGS 236
P P P Q+ G ++ED+A + P G+PG
Sbjct: 1405 PGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAP-------GSPGGLEEI 1457
Query: 237 RGRLNSFTQGI 247
G L+S + I
Sbjct: 1458 FGSLDSLREEI 1468
Score = 32.0 bits (71), Expect = 1.8
Identities = 55/211 (26%), Positives = 65/211 (30%), Gaps = 22/211 (10%)
Query: 16 GSAGTDAAGASGLQQPPPQPQPQPAAAAPAQPPPEPPRKPRMDPRRRQAALSFLTNISLD 75
GS G D Q+ Q Q A A PP R P + +
Sbjct: 371 GSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDL 430
Query: 76 GRLPPQDAEWGGGEEGGAAKPGAGGACGARTR-----------FSLLAA-----AERGGC 119
G P+ + G G A + G GA GAR F L RG
Sbjct: 431 GPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDT 490
Query: 120 IALAAPGTPAAGLAAGS----GPC-LPQPSSLPPLI-PGGHATVSGPGVARGFASPLGAG 173
A PG P G GP LP S L+ P G + GP RG P G
Sbjct: 491 GAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPK 550
Query: 174 RASGEQWQPPRPAPLAACAQLQLLDGSGAAG 204
+ G Q +P P L GA G
Sbjct: 551 GSLGPQGEPGPPGQQGTPGTQGLPGPQGAIG 581
>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo
sapiens]
Length = 1629
Score = 48.1 bits (113), Expect = 2e-05
Identities = 51/197 (25%), Positives = 74/197 (37%), Gaps = 9/197 (4%)
Query: 15 SGSAGTDAAGASGLQQPPPQPQPQPAAAAPAQPPPEPPRKPRMD--PRRRQAALSFLTNI 72
SGS G G G++ P + + + P +P P P+ P D P+ + F +
Sbjct: 1111 SGSPGIQ--GEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDP 1168
Query: 73 SLDGRLPP--QDAEWGG-GEEGGAAKPGAGGACGARTRFSLLAAAERGGCIALAAPGTPA 129
G P QD G GE+G +PG+ G G L +RG + + G
Sbjct: 1169 GPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLG--KRGPAGSPGSEGRQG 1226
Query: 130 AGLAAGSGPCLPQPSSLPPLIPGGHATVSGPGVARGFASPLGAGRASGEQWQPPRPAPLA 189
A G + P P+ P G A GP RG +G G Q P P+
Sbjct: 1227 GKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVG 1286
Query: 190 ACAQLQLLDGSGAAGQE 206
L +GA G++
Sbjct: 1287 PPGLPGLRGDAGAKGEK 1303
Score = 37.4 bits (85), Expect = 0.042
Identities = 50/176 (28%), Positives = 61/176 (34%), Gaps = 20/176 (11%)
Query: 16 GSAG-TDAAGASGLQQPPPQPQ----PQPAAAAPAQPPPEPPRKPRMDPRRRQAALSFLT 70
G+AG T G G PP P P A + P PP P D + L
Sbjct: 824 GAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKD------GPAGLR 877
Query: 71 NISLDGRLPPQDAEWG-GGEEGGAAKPGAGGACGARTRFSLLAAAERGGCIALAAPGTPA 129
+ LP G G EG + PG G+ G R AA GG I PG P
Sbjct: 878 GFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGER------GAAGSGGPIG--PPGRPG 929
Query: 130 AGLAAGSGPCLPQPSSLPPLIPGGHATVSGPGVARGFASPLGAGRASGEQWQPPRP 185
G+ P P+ P G V GP G A P G G++ + P
Sbjct: 930 PQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDP 985
Score = 36.6 bits (83), Expect = 0.072
Identities = 56/193 (29%), Positives = 67/193 (34%), Gaps = 25/193 (12%)
Query: 11 AACSSGSAGTDAAGASGLQQPPPQ---PQPQPAAAAPA-QPPPEPPRK---PRMDPRRRQ 63
A SG+ GT +G G PP + P PQ P + PP PP K P +R +
Sbjct: 747 ATGKSGAKGT--SGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGE 804
Query: 64 AALSFLTNI-SLDGRLPPQDAEWGGGEEGGAAKPGAGGACGARTRFSLLAAAERGGCIAL 122
T G + PQ A G G PG G G + L A + G
Sbjct: 805 VGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQ---GLPGTAGKEG--TK 859
Query: 123 AAPGTPAAGLAAGSGPC----LPQPSSLPPLIPG----GHATVSGPGVARGFASPLGAGR 174
PG P G GP P LP G G+ SGP G GA
Sbjct: 860 GDPGPP--GAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAG 917
Query: 175 ASGEQWQPPRPAP 187
+ G P RP P
Sbjct: 918 SGGPIGPPGRPGP 930
Score = 35.8 bits (81), Expect = 0.12
Identities = 57/251 (22%), Positives = 77/251 (30%), Gaps = 37/251 (14%)
Query: 15 SGSAGTDAAGASGLQQPPPQPQPQPAAAAPAQPPPEPPRKPRMDPRRRQAALSFLTNISL 74
+GS G++ + P P P P P KP D R L
Sbjct: 1216 AGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAG-PAGKPGPDGLR-----------GL 1263
Query: 75 DGRLPPQDAEWGGGEEGGAAKPGAGGACGARTRFSLLAAAERGGCIALAAP--------- 125
G + Q G+ G G G G R G I L P
Sbjct: 1264 PGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGD 1323
Query: 126 -GTPAAGLAAGSGPCLPQPSSLPPLIPGGHATVSGPGVARGFASPLGAGRASGE---QWQ 181
G P + G + P + P+ PGG + GP +G G G GE Q
Sbjct: 1324 RGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGP 1383
Query: 182 PPRPAPLAAC-----AQLQLLDGSGAAGQEELEEDDAFISVQVPAAAFLGSGTPGSGSGS 236
P P P Q+ G ++ED+A + P G+PG
Sbjct: 1384 PGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAP-------GSPGGLEEI 1436
Query: 237 RGRLNSFTQGI 247
G L+S + I
Sbjct: 1437 FGSLDSLREEI 1447
Score = 32.0 bits (71), Expect = 1.8
Identities = 55/211 (26%), Positives = 65/211 (30%), Gaps = 22/211 (10%)
Query: 16 GSAGTDAAGASGLQQPPPQPQPQPAAAAPAQPPPEPPRKPRMDPRRRQAALSFLTNISLD 75
GS G D Q+ Q Q A A PP R P + +
Sbjct: 350 GSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDL 409
Query: 76 GRLPPQDAEWGGGEEGGAAKPGAGGACGARTR-----------FSLLAA-----AERGGC 119
G P+ + G G A + G GA GAR F L RG
Sbjct: 410 GPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDT 469
Query: 120 IALAAPGTPAAGLAAGS----GPC-LPQPSSLPPLI-PGGHATVSGPGVARGFASPLGAG 173
A PG P G GP LP S L+ P G + GP RG P G
Sbjct: 470 GAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPK 529
Query: 174 RASGEQWQPPRPAPLAACAQLQLLDGSGAAG 204
+ G Q +P P L GA G
Sbjct: 530 GSLGPQGEPGPPGQQGTPGTQGLPGPQGAIG 560
>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo
sapiens]
Length = 1736
Score = 48.1 bits (113), Expect = 2e-05
Identities = 51/197 (25%), Positives = 74/197 (37%), Gaps = 9/197 (4%)
Query: 15 SGSAGTDAAGASGLQQPPPQPQPQPAAAAPAQPPPEPPRKPRMD--PRRRQAALSFLTNI 72
SGS G G G++ P + + + P +P P P+ P D P+ + F +
Sbjct: 1218 SGSPGIQ--GEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDP 1275
Query: 73 SLDGRLPP--QDAEWGG-GEEGGAAKPGAGGACGARTRFSLLAAAERGGCIALAAPGTPA 129
G P QD G GE+G +PG+ G G L +RG + + G
Sbjct: 1276 GPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLG--KRGPAGSPGSEGRQG 1333
Query: 130 AGLAAGSGPCLPQPSSLPPLIPGGHATVSGPGVARGFASPLGAGRASGEQWQPPRPAPLA 189
A G + P P+ P G A GP RG +G G Q P P+
Sbjct: 1334 GKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVG 1393
Query: 190 ACAQLQLLDGSGAAGQE 206
L +GA G++
Sbjct: 1394 PPGLPGLRGDAGAKGEK 1410
Score = 37.4 bits (85), Expect = 0.042
Identities = 50/176 (28%), Positives = 61/176 (34%), Gaps = 20/176 (11%)
Query: 16 GSAG-TDAAGASGLQQPPPQPQ----PQPAAAAPAQPPPEPPRKPRMDPRRRQAALSFLT 70
G+AG T G G PP P P A + P PP P D + L
Sbjct: 931 GAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKD------GPAGLR 984
Query: 71 NISLDGRLPPQDAEWG-GGEEGGAAKPGAGGACGARTRFSLLAAAERGGCIALAAPGTPA 129
+ LP G G EG + PG G+ G R AA GG I PG P
Sbjct: 985 GFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGER------GAAGSGGPIG--PPGRPG 1036
Query: 130 AGLAAGSGPCLPQPSSLPPLIPGGHATVSGPGVARGFASPLGAGRASGEQWQPPRP 185
G+ P P+ P G V GP G A P G G++ + P
Sbjct: 1037 PQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDP 1092
Score = 36.6 bits (83), Expect = 0.072
Identities = 56/193 (29%), Positives = 67/193 (34%), Gaps = 25/193 (12%)
Query: 11 AACSSGSAGTDAAGASGLQQPPPQ---PQPQPAAAAPA-QPPPEPPRK---PRMDPRRRQ 63
A SG+ GT +G G PP + P PQ P + PP PP K P +R +
Sbjct: 854 ATGKSGAKGT--SGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGE 911
Query: 64 AALSFLTNI-SLDGRLPPQDAEWGGGEEGGAAKPGAGGACGARTRFSLLAAAERGGCIAL 122
T G + PQ A G G PG G G + L A + G
Sbjct: 912 VGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQ---GLPGTAGKEG--TK 966
Query: 123 AAPGTPAAGLAAGSGPC----LPQPSSLPPLIPG----GHATVSGPGVARGFASPLGAGR 174
PG P G GP P LP G G+ SGP G GA
Sbjct: 967 GDPGPP--GAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAG 1024
Query: 175 ASGEQWQPPRPAP 187
+ G P RP P
Sbjct: 1025 SGGPIGPPGRPGP 1037
Score = 35.8 bits (81), Expect = 0.12
Identities = 57/251 (22%), Positives = 77/251 (30%), Gaps = 37/251 (14%)
Query: 15 SGSAGTDAAGASGLQQPPPQPQPQPAAAAPAQPPPEPPRKPRMDPRRRQAALSFLTNISL 74
+GS G++ + P P P P P KP D R L
Sbjct: 1323 AGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAG-PAGKPGPDGLR-----------GL 1370
Query: 75 DGRLPPQDAEWGGGEEGGAAKPGAGGACGARTRFSLLAAAERGGCIALAAP--------- 125
G + Q G+ G G G G R G I L P
Sbjct: 1371 PGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGD 1430
Query: 126 -GTPAAGLAAGSGPCLPQPSSLPPLIPGGHATVSGPGVARGFASPLGAGRASGE---QWQ 181
G P + G + P + P+ PGG + GP +G G G GE Q
Sbjct: 1431 RGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGP 1490
Query: 182 PPRPAPLAAC-----AQLQLLDGSGAAGQEELEEDDAFISVQVPAAAFLGSGTPGSGSGS 236
P P P Q+ G ++ED+A + P G+PG
Sbjct: 1491 PGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAP-------GSPGGLEEI 1543
Query: 237 RGRLNSFTQGI 247
G L+S + I
Sbjct: 1544 FGSLDSLREEI 1554
Score = 32.0 bits (71), Expect = 1.8
Identities = 55/211 (26%), Positives = 65/211 (30%), Gaps = 22/211 (10%)
Query: 16 GSAGTDAAGASGLQQPPPQPQPQPAAAAPAQPPPEPPRKPRMDPRRRQAALSFLTNISLD 75
GS G D Q+ Q Q A A PP R P + +
Sbjct: 457 GSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDL 516
Query: 76 GRLPPQDAEWGGGEEGGAAKPGAGGACGARTR-----------FSLLAA-----AERGGC 119
G P+ + G G A + G GA GAR F L RG
Sbjct: 517 GPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDT 576
Query: 120 IALAAPGTPAAGLAAGS----GPC-LPQPSSLPPLI-PGGHATVSGPGVARGFASPLGAG 173
A PG P G GP LP S L+ P G + GP RG P G
Sbjct: 577 GAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPK 636
Query: 174 RASGEQWQPPRPAPLAACAQLQLLDGSGAAG 204
+ G Q +P P L GA G
Sbjct: 637 GSLGPQGEPGPPGQQGTPGTQGLPGPQGAIG 667
>gi|154146199 sal-like 3 [Homo sapiens]
Length = 1300
Score = 47.8 bits (112), Expect = 3e-05
Identities = 47/151 (31%), Positives = 59/151 (39%), Gaps = 29/151 (19%)
Query: 28 LQQPPPQPQPQPAAAAPAQPPPEPPRKPRM--------DPRRRQAALSFLTNISLDGRLP 79
+Q+PPP+P PAAA P+ P P P + P + P A + +G P
Sbjct: 233 MQRPPPRPSLSPAAA-PSAPGPAPSQLPGLAALPLSAGAPAAAIAGSGPAAPAAFEGAQP 291
Query: 80 PQDAEWGGGEEGGAAKPGAGGACGARTRFSLLAAAERGGCIALAAPGTPAAGLAAGSGPC 139
E G GG A+P A A A A AAP A +A S
Sbjct: 292 LSRPESGASTPGGPAEPSAPAAPSAAP--------------APAAPAPAPAPQSAASSQ- 336
Query: 140 LPQPSSLPPLIPGGHATVSGPGVARGFASPL 170
PQ +S PP + G S G A G SPL
Sbjct: 337 -PQSASTPPALAPG----SLLGAAPGLPSPL 362
>gi|142976757 immediate early response 5 [Homo sapiens]
Length = 327
Score = 46.6 bits (109), Expect = 7e-05
Identities = 60/205 (29%), Positives = 78/205 (38%), Gaps = 48/205 (23%)
Query: 19 GTDAAGASGLQQPPPQPQP-QPAAAAPA---QPPPEPPRK--PRMDPRRRQAALSFLTNI 72
G AG +G PPPQ QP +PAA PA +PPP R P +P+ ++++S +
Sbjct: 54 GLYLAGPAGTPAPPPQQQPGEPAAGPPAGWGEPPPPAARASWPETEPQPERSSVSDAPRV 113
Query: 73 SLD---------------GRLPPQDAEWG--GGEEGGAAKPGAGGACGARTRFSLLAAAE 115
+ G +A W G AA+ G A G + AA
Sbjct: 114 GDEVPVATVTGVGDVFQGGEADATEAAWSRVEGPRQAAAREAEGTAGGWGVFPEVSRAAR 173
Query: 116 RGGCIALAA---PGTPAAGLAAGSGPCLPQPSSLPPLIP--------------GGHATVS 158
R L PGTPAA A C PQP+ P P GG A
Sbjct: 174 RPCGCPLGGEDPPGTPAATPRAAC-CCAPQPAEDEPPAPPAVCPRKRCAAGVGGGPAGCP 232
Query: 159 GPGVARGFASPLGAGRASGEQWQPP 183
PG ++PL R + E QPP
Sbjct: 233 APG-----STPLKKPRRNLE--QPP 250
>gi|118766337 zinc finger protein of the cerebellum 5 [Homo sapiens]
Length = 663
Score = 46.2 bits (108), Expect = 9e-05
Identities = 51/172 (29%), Positives = 60/172 (34%), Gaps = 35/172 (20%)
Query: 2 AAAAAAATTAACSSGSAGTDAAGASGLQQPPPQPQPQPAAAAPAQPPPEPPRKPRMDPRR 61
AAAA AA A + G+SG Q P P P P+ PPP PP P
Sbjct: 119 AAAARAAALVAHPGAGSYPCGGGSSGAQPSAPPPPAPPLPPTPSPPPPPPPPPP------ 172
Query: 62 RQAALSFLTNISLDGRLPPQDAEWGGGEEGGAAKPGAGGACGARTRFSLLAAAERGGCIA 121
ALS T + GG G G + R L A A A
Sbjct: 173 --PALSGYTTTN----------------SGGGGSSGKGHSRDFVLRRDLSATAP-----A 209
Query: 122 LAAPGTPAAGLAAGSGPCLPQPSSLPPLIPGGHATVSGPGVARGFASPLGAG 173
A G P G SG PQ + PP G + SG +A P G+G
Sbjct: 210 AAMHGAPLGG-EQRSGTGSPQHPAPPPHSAGMFISASGT-----YAGPDGSG 255
Score = 44.7 bits (104), Expect = 3e-04
Identities = 62/243 (25%), Positives = 85/243 (34%), Gaps = 27/243 (11%)
Query: 2 AAAAAAATTAACSSGS--AGTDAAGASGLQQPPPQPQPQPAAAAPAQPPPEPPRKPRMD- 58
AAA AAA A +GS G ++GA PPP P P + P PPP PP P +
Sbjct: 120 AAARAAALVAHPGAGSYPCGGGSSGAQPSAPPPPAPPLPPTPSPPPPPPPPPP--PALSG 177
Query: 59 ----------PRRRQAALSFLTNISLDGRLPPQDAEWGGGEEGGAAKPGAGGACGARTRF 108
+ + F+ L P A G GG + G G
Sbjct: 178 YTTTNSGGGGSSGKGHSRDFVLRRDLSATAPA--AAMHGAPLGGEQRSGTGSPQHP---- 231
Query: 109 SLLAAAERGGCIALAAPGTPAAGLAAGSGPCLPQPSSLPPLIPGGHATVSGPGVARGFAS 168
A + ++A GT AG GP L P PGGH + G A+
Sbjct: 232 ---APPPHSAGMFISASGT-YAGPDGSGGPALFPALHDTPGAPGGHPHPLNGQMRLGLAA 287
Query: 169 PLGAGRASGEQWQPPRPAPLAACAQLQLLDGSGAAGQEELEEDDAFISVQVPAAAFLGSG 228
A A P AP + A + + AA + +++ + AAA +
Sbjct: 288 AAAAAAAELYGRAEPPFAPRSGDAHYGAVAAAAAAALHGYGAVN--LNLNLAAAAAAAAA 345
Query: 229 TPG 231
PG
Sbjct: 346 GPG 348
Score = 30.4 bits (67), Expect = 5.2
Identities = 18/50 (36%), Positives = 22/50 (44%)
Query: 3 AAAAAATTAACSSGSAGTDAAGASGLQQPPPQPQPQPAAAAPAQPPPEPP 52
AAAAAA + + + A A+ P P Q A PA PPP P
Sbjct: 317 AAAAAAALHGYGAVNLNLNLAAAAAAAAAGPGPHLQHHAPPPAPPPPPAP 366
>gi|156071470 hyperpolarization activated cyclic nucleotide-gated
potassium channel 2 [Homo sapiens]
Length = 889
Score = 45.8 bits (107), Expect = 1e-04
Identities = 46/179 (25%), Positives = 58/179 (32%), Gaps = 47/179 (26%)
Query: 12 ACSSGSAGTDAAGASGLQQPPPQPQP-----QPAAAAPAQPPPEPPRKPRMDPRRRQAAL 66
A G ++ GA+ PPP P P QP P PPP P P P R +A
Sbjct: 3 ARGGGGRPGESPGATPAPGPPPPPPPAPPQQQPPPPPPPAPPPGPGPAPPQHPPRAEA-- 60
Query: 67 SFLTNISLDGRLPPQDAEWGG------GEEGGAAKPGAGGACGARTRFSLLAAAERGGCI 120
LPP+ A+ GG + +PG GA
Sbjct: 61 -----------LPPEAADEGGPRGRLRSRDSSCGRPGTPGA------------------- 90
Query: 121 ALAAPGTPAAGLAAGSGPCLPQ----PSSLPPLIPGGHATVSGPGVARGFASPLGAGRA 175
A A G+P G C P P+ P + SGP G A G+ A
Sbjct: 91 ASTAKGSPNGECGRGEPQCSPAGPEGPARGPKVSFSCRGAASGPAPGPGPAEEAGSEEA 149
Score = 41.6 bits (96), Expect = 0.002
Identities = 55/173 (31%), Positives = 69/173 (39%), Gaps = 35/173 (20%)
Query: 4 AAAAATTAACSSGSAGTDAAGASGLQQPPPQPQPQPAAAAPAQPPPEPPRKPRMDPRRRQ 63
AAA + + G A G+ L + PP P P PAAA+P PPP P PR
Sbjct: 733 AAAMSFCPQVARPLVGPLALGSPRLVRRPP-PGPAPAAASPGPPPPASPPGAPASPR--- 788
Query: 64 AALSFLTNISLDGRLPPQDAEWGGGEEGGAAKPGAGGACGARTRFSLLAAAERGGCIALA 123
P+ + +G G A P AG A AR L+ A R ++ +
Sbjct: 789 ---------------APRTSPYG----GLPAAPLAGPALPARR----LSRASRP--LSAS 823
Query: 124 APGTP--AAGLAAGSGPCLPQPSSLPPLIPGGHATVSGPGV-ARGFASPLGAG 173
P P A G AA + P SS P L P A + P R ASP AG
Sbjct: 824 QPSLPHGAPGPAASTRPA---SSSTPRLGPTPAARAAAPSPDRRDSASPGAAG 873
Score = 35.4 bits (80), Expect = 0.16
Identities = 53/182 (29%), Positives = 57/182 (31%), Gaps = 43/182 (23%)
Query: 21 DAAGASGLQQPPPQPQPQPAAAAP-------AQPPPEPPRKPRMDPRRRQAALSFLTNIS 73
DA G G P P P P QPPP PP P P
Sbjct: 2 DARGGGGRPGESPGATPAPGPPPPPPPAPPQQQPPPPPPPAPPPGP-------------- 47
Query: 74 LDGRLPPQDAEWGGGEEGGAAKPGAGGACGARTRFSLLAAAERGGCIALAAPGTP-AAGL 132
G PPQ A P A G R R R + PGTP AA
Sbjct: 48 --GPAPPQHP-----PRAEALPPEAADEGGPRGRL-------RSRDSSCGRPGTPGAAST 93
Query: 133 AAGS--GPC---LPQPSSLPPLIP--GGHATVSGPGVARGFASPLGAGRASGEQWQPPRP 185
A GS G C PQ S P P G + S G A G A G +G + P
Sbjct: 94 AKGSPNGECGRGEPQCSPAGPEGPARGPKVSFSCRGAASGPAPGPGPAEEAGSEEAGPAG 153
Query: 186 AP 187
P
Sbjct: 154 EP 155
>gi|12707580 paired-like homeobox 2b [Homo sapiens]
Length = 314
Score = 45.8 bits (107), Expect = 1e-04
Identities = 41/143 (28%), Positives = 50/143 (34%), Gaps = 15/143 (10%)
Query: 5 AAAATTAACSSGSAGTDAAGASGLQQPPPQPQPQPAAAAPAQPPPEPPRKPRMDPRRRQA 64
AAAA AA +GS+G + + + + + P P P
Sbjct: 159 AAAAAAAAAKNGSSGKKSDSSRDDESKEAKSTDPDSTGGPGPNPNPTP------------ 206
Query: 65 ALSFLTNISLDGRLPPQDAEWGGGEEGGAAKPGAGGACGARTRFSLLAAAERGGCIA-LA 123
S N G P A G G +PG GGA A + AAA LA
Sbjct: 207 --SCGANGGGGGGPSPAGAPGAAGPGGPGGEPGKGGAAAAAAAAAAAAAAAAAAAAGGLA 264
Query: 124 APGTPAAGLAAGSGPCLPQPSSL 146
A G P G A G GP P SL
Sbjct: 265 AAGGPGQGWAPGPGPITSIPDSL 287
>gi|57222568 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 6 [Homo sapiens]
Length = 1093
Score = 45.8 bits (107), Expect = 1e-04
Identities = 76/331 (22%), Positives = 114/331 (34%), Gaps = 44/331 (13%)
Query: 12 ACSSGSAGTDAAGASGLQQPPPQPQPQPAAAAPAQPP-PEPPRKPRMDPRRRQAALS--- 67
A SS + D + L+QP +P A AP+ PP P P P+ D ++ S
Sbjct: 345 AVSSLQSSPDFSAFPKLEQPEEDKYSKPTAPAPSAPPSPSAPEPPKADLFEQKVVFSGFG 404
Query: 68 ----FLTNISLDGRLPPQDAEWGGGEEGGAAKPGAGGACGARTRFSLLAAAERGGCIALA 123
F T S GR G+ G+G + G R L+A +
Sbjct: 405 PIMRFSTTTSSSGRARAPSP----GDYKSPHVTGSGASAGTHKRMPALSAT------PVP 454
Query: 124 APGTPAAGL---------AAGSGPCLPQPS------------SLPPLIPGGHATVSGPGV 162
A TP GL + GP P+ S SLP G +
Sbjct: 455 ADETPETGLKEKKHKASKRSRHGPGRPKGSRNKEGTGGPAAPSLPSAQLAGFTATAASPF 514
Query: 163 ARGFASPLGAGRASGEQWQPPRPAPLAACAQLQLLDGSGAAGQEELEEDDAFISV--QVP 220
+ G G G S + P P + L G + ++ + + P
Sbjct: 515 SGGSLVSSGLGGLSSRTFGPSGSLPSLSLESPLLGAGIYTSNKDPISHSGGMLRAVCSTP 574
Query: 221 AAAFLGSGTPGSGSGSRGRLNSFTQGILPIAFSRPTSQNYCSLEQPGQGGSTSAFEQLQR 280
++ L G PG+ + R + FT + + S T+Q + ST F
Sbjct: 575 LSSSL-LGPPGTSALPRLSRSPFTSTLPSSSASISTTQVFSLAGSTFSLPSTHIFGTPMG 633
Query: 281 SRRRLISQRSSLETLEDIEENAPLRRCRTLS 311
+ L+SQ S T D+E+ + RCR S
Sbjct: 634 AVNPLLSQAESSHTEPDLEDCS--FRCRGTS 662
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 45.8 bits (107), Expect = 1e-04
Identities = 45/171 (26%), Positives = 63/171 (36%), Gaps = 30/171 (17%)
Query: 27 GLQQPPPQPQPQPAAAAPAQPPPEPPRKPRMDPRRRQAALSFLTNISLDGRLPPQDAEWG 86
G+ +P P P P P + P PPR+ A+ + GR PP +
Sbjct: 2247 GVVRPAPPPPPPPLTLVLSSGPASPPRQ----------AIRVKRVSTFSGRSPPAPPPYK 2296
Query: 87 G---GEEGGAAK-----PGAGGACGARTRFSLLAAAERGGCIALAAPGTPAAGLAAG--- 135
E+G A++ PG G +R R G + L PG PA + G
Sbjct: 2297 APRLDEDGEASEDTPQVPGLGSGGFSRVRMKTPTVR---GVLDLDRPGEPAGEESPGPLQ 2353
Query: 136 -SGPCLPQPSSLPPLIPGGHATVSGPGVARGFASPLGAGRASGEQWQPPRP 185
P LP P PP +P G P + +G AS + +PP P
Sbjct: 2354 ERSPLLPLPEDGPPQVPDG-----PPDLLLESQWHHYSGEASSSEEEPPSP 2399
Score = 31.6 bits (70), Expect = 2.3
Identities = 12/25 (48%), Positives = 13/25 (52%)
Query: 31 PPPQPQPQPAAAAPAQPPPEPPRKP 55
PPP P P + P PPP PP P
Sbjct: 414 PPPLPPPSTSPPPPLCPPPPPPVSP 438
Score = 30.4 bits (67), Expect = 5.2
Identities = 12/29 (41%), Positives = 12/29 (41%)
Query: 31 PPPQPQPQPAAAAPAQPPPEPPRKPRMDP 59
PPP P P P PP PP P P
Sbjct: 418 PPPSTSPPPPLCPPPPPPVSPPPLPSPPP 446
>gi|42519916 forkhead box O3A [Homo sapiens]
Length = 673
Score = 45.4 bits (106), Expect = 2e-04
Identities = 39/139 (28%), Positives = 51/139 (36%), Gaps = 14/139 (10%)
Query: 28 LQQPPPQPQPQPAAAAPAQPPPEPPRKPR------MDPRRRQAALSFLTNISLDGRLPPQ 81
+ + P P P P EP +PR P + + + D +P +
Sbjct: 1 MAEAPASPAPLSPLEVELDPEFEPQSRPRSCTWPLQRPELQASPAKPSGETAADSMIPEE 60
Query: 82 ----DAEWGGGEEGGAAKPGAGGACGARTRFSLLAAAER----GGCIALAAPGTPAAGLA 133
D E GGG G A G GG G LL + R GG + P T A GL+
Sbjct: 61 EDDEDDEDGGGRAGSAMAIGGGGGSGTLGSGLLLEDSARVLAPGGQDPGSGPATAAGGLS 120
Query: 134 AGSGPCLPQPSSLPPLIPG 152
G+ L LPP PG
Sbjct: 121 GGTQALLQPQQPLPPPQPG 139
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.134 0.395
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,715,778
Number of Sequences: 37866
Number of extensions: 1728638
Number of successful extensions: 31082
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 446
Number of HSP's successfully gapped in prelim test: 1009
Number of HSP's that attempted gapping in prelim test: 18036
Number of HSP's gapped (non-prelim): 9397
length of query: 633
length of database: 18,247,518
effective HSP length: 108
effective length of query: 525
effective length of database: 14,157,990
effective search space: 7432944750
effective search space used: 7432944750
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.