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Search of human proteins with 154759291
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|154759291 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 10 [Homo sapiens]
(444 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|154759291 serine (or cysteine) proteinase inhibitor, clade A ... 885 0.0
gi|7705879 serine (or cysteine) proteinase inhibitor, clade A (a... 885 0.0
gi|27777657 serine (or cysteine) proteinase inhibitor, clade A (... 216 4e-56
gi|189163542 serine proteinase inhibitor, clade A, member 1 [Hom... 213 2e-55
gi|189163540 serine proteinase inhibitor, clade A, member 1 [Hom... 213 2e-55
gi|189163538 serine proteinase inhibitor, clade A, member 1 [Hom... 213 2e-55
gi|189163536 serine proteinase inhibitor, clade A, member 1 [Hom... 213 2e-55
gi|189163534 serine proteinase inhibitor, clade A, member 1 [Hom... 213 2e-55
gi|189163532 serine proteinase inhibitor, clade A, member 1 [Hom... 213 2e-55
gi|189163530 serine proteinase inhibitor, clade A, member 1 [Hom... 213 2e-55
gi|189163528 serine proteinase inhibitor, clade A, member 1 [Hom... 213 2e-55
gi|50363219 serine proteinase inhibitor, clade A, member 1 [Homo... 213 2e-55
gi|50363221 serine proteinase inhibitor, clade A, member 1 [Homo... 213 2e-55
gi|50363217 serine proteinase inhibitor, clade A, member 1 [Homo... 213 2e-55
gi|50659080 serpin peptidase inhibitor, clade A, member 3 precur... 202 5e-52
gi|194018472 serine (or cysteine) proteinase inhibitor, clade A ... 190 2e-48
gi|205277441 serine (or cysteine) proteinase inhibitor, clade A,... 189 4e-48
gi|110225347 serine (or cysteine) proteinase inhibitor, clade A ... 186 3e-47
gi|73858564 corticosteroid binding globulin precursor [Homo sapi... 186 5e-47
gi|73858566 heparin cofactor II precursor [Homo sapiens] 181 9e-46
gi|5453886 serpin peptidase inhibitor, clade I (pancpin), member... 169 6e-42
gi|13489087 serine (or cysteine) proteinase inhibitor, clade B (... 167 2e-41
gi|21361302 serine (or cysteine) proteinase inhibitor, clade A (... 164 1e-40
gi|170295807 neuroserpin precursor [Homo sapiens] 163 3e-40
gi|4826904 neuroserpin precursor [Homo sapiens] 163 3e-40
gi|122937297 serpin peptidase inhibitor, clade A (alpha-1 antipr... 162 6e-40
gi|4758906 serpin peptidase inhibitor, clade B, member 9 [Homo s... 159 4e-39
gi|4502261 serpin peptidase inhibitor, clade C, member 1 [Homo s... 158 1e-38
gi|156071456 serpin peptidase inhibitor, clade B, member 11 [Hom... 154 2e-37
gi|41152086 serine (or cysteine) proteinase inhibitor, clade B (... 151 1e-36
>gi|154759291 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 10 [Homo
sapiens]
Length = 444
Score = 885 bits (2288), Expect = 0.0
Identities = 444/444 (100%), Positives = 444/444 (100%)
Query: 1 MKVVPSLLLSVLLAQVWLVPGLAPSPQSPETPAPQNQTSRVVQAPKEEEEDEQEASEEKA 60
MKVVPSLLLSVLLAQVWLVPGLAPSPQSPETPAPQNQTSRVVQAPKEEEEDEQEASEEKA
Sbjct: 1 MKVVPSLLLSVLLAQVWLVPGLAPSPQSPETPAPQNQTSRVVQAPKEEEEDEQEASEEKA 60
Query: 61 SEEEKAWLMASRQQLAKETSNFGFSLLRKISMRHDGNMVFSPFGMSLAMTGLMLGATGPT 120
SEEEKAWLMASRQQLAKETSNFGFSLLRKISMRHDGNMVFSPFGMSLAMTGLMLGATGPT
Sbjct: 61 SEEEKAWLMASRQQLAKETSNFGFSLLRKISMRHDGNMVFSPFGMSLAMTGLMLGATGPT 120
Query: 121 ETQIKRGLHLQALKPTKPGLLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFN 180
ETQIKRGLHLQALKPTKPGLLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFN
Sbjct: 121 ETQIKRGLHLQALKPTKPGLLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFN 180
Query: 181 LSKRYFDTECVPMNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKG 240
LSKRYFDTECVPMNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKG
Sbjct: 181 LSKRYFDTECVPMNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKG 240
Query: 241 KWLTPFDPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLV 300
KWLTPFDPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLV
Sbjct: 241 KWLTPFDPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLV 300
Query: 301 VLMEKMGDHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRI 360
VLMEKMGDHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRI
Sbjct: 301 VLMEKMGDHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRI 360
Query: 361 FSPFADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVDRPF 420
FSPFADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVDRPF
Sbjct: 361 FSPFADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVDRPF 420
Query: 421 HFMIYEETSGMLLFLGRVVNPTLL 444
HFMIYEETSGMLLFLGRVVNPTLL
Sbjct: 421 HFMIYEETSGMLLFLGRVVNPTLL 444
>gi|7705879 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 10 [Homo
sapiens]
Length = 444
Score = 885 bits (2288), Expect = 0.0
Identities = 444/444 (100%), Positives = 444/444 (100%)
Query: 1 MKVVPSLLLSVLLAQVWLVPGLAPSPQSPETPAPQNQTSRVVQAPKEEEEDEQEASEEKA 60
MKVVPSLLLSVLLAQVWLVPGLAPSPQSPETPAPQNQTSRVVQAPKEEEEDEQEASEEKA
Sbjct: 1 MKVVPSLLLSVLLAQVWLVPGLAPSPQSPETPAPQNQTSRVVQAPKEEEEDEQEASEEKA 60
Query: 61 SEEEKAWLMASRQQLAKETSNFGFSLLRKISMRHDGNMVFSPFGMSLAMTGLMLGATGPT 120
SEEEKAWLMASRQQLAKETSNFGFSLLRKISMRHDGNMVFSPFGMSLAMTGLMLGATGPT
Sbjct: 61 SEEEKAWLMASRQQLAKETSNFGFSLLRKISMRHDGNMVFSPFGMSLAMTGLMLGATGPT 120
Query: 121 ETQIKRGLHLQALKPTKPGLLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFN 180
ETQIKRGLHLQALKPTKPGLLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFN
Sbjct: 121 ETQIKRGLHLQALKPTKPGLLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFN 180
Query: 181 LSKRYFDTECVPMNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKG 240
LSKRYFDTECVPMNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKG
Sbjct: 181 LSKRYFDTECVPMNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKG 240
Query: 241 KWLTPFDPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLV 300
KWLTPFDPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLV
Sbjct: 241 KWLTPFDPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLV 300
Query: 301 VLMEKMGDHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRI 360
VLMEKMGDHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRI
Sbjct: 301 VLMEKMGDHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRI 360
Query: 361 FSPFADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVDRPF 420
FSPFADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVDRPF
Sbjct: 361 FSPFADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVDRPF 420
Query: 421 HFMIYEETSGMLLFLGRVVNPTLL 444
HFMIYEETSGMLLFLGRVVNPTLL
Sbjct: 421 HFMIYEETSGMLLFLGRVVNPTLL 444
>gi|27777657 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 12 [Homo
sapiens]
Length = 414
Score = 216 bits (549), Expect = 4e-56
Identities = 119/385 (30%), Positives = 212/385 (55%), Gaps = 6/385 (1%)
Query: 59 KASEEEKAWLMA-SRQQLAKETSNFGFSLLRKISMRHDGNMVF-SPFGMSLAMTGLMLGA 116
KA E + W + ++LA++ + GF LL+K++ + G +F SP +S A + L LGA
Sbjct: 31 KALSEVQGWKQRMAAKELARQNMDLGFKLLKKLAFYNPGRNIFLSPLSISTAFSMLCLGA 90
Query: 117 TGPTETQIKRGLHLQALKPTKPGLLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKE 176
T +IK+G + + K + L + E + +L L+ G+ FI + +
Sbjct: 91 QDSTLDEIKQGFNFR--KMPEKDLHEGFHYIIHELTQKTQDLKLSIGNTLFIDQRLQPQR 148
Query: 177 TFFNLSKRYFDTECVPMNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYI 236
F +K ++ E + NF+N A++ +N +I+++T GKI L + I+P T ++L +YI
Sbjct: 149 KFLEDAKNFYSAETILTNFQNLEMAQKQINDFISQKTHGKINNLIENIDPGTVMLLANYI 208
Query: 237 LFKGKWLTPFDPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNA 296
F+ +W FDP T+ + F L+K ++KVPMM+ +G + +D C +L++PYQ N
Sbjct: 209 FFRARWKHEFDPNVTKEEDFFLEKNSSVKVPMMFRSGIYQVGYDDKLSCTILEIPYQKNI 268
Query: 297 TMLVVLMEKMGDHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMG 356
T + +L ++ G LE L D W + R ++V P+ + +++ + L +G
Sbjct: 269 TAIFILPDE-GKLKHLEKGLQVDTFSRWKTLLSRRVVDVSVPRLHMTGTFDLKKTLSYIG 327
Query: 357 IRRIFSPFADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKV 416
+ +IF DL+++ A R+L+V + + +++DERGTE AG ++ P V+K+
Sbjct: 328 VSKIFEEHGDLTKI-APHRSLKVGEAVHKAELKMDERGTEGAAGTGAQTLPMETPLVVKI 386
Query: 417 DRPFHFMIYEETSGMLLFLGRVVNP 441
D+P+ +IY E +LFLG++VNP
Sbjct: 387 DKPYLLLIYSEKIPSVLFLGKIVNP 411
>gi|189163542 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 213 bits (543), Expect = 2e-55
Identities = 127/399 (31%), Positives = 211/399 (52%), Gaps = 3/399 (0%)
Query: 45 PKEEEEDEQEASEEKASEEEKAWLMASRQQLAKETSNFGFSLLRKISMRHDG-NMVFSPF 103
P ED Q + +K + ++ + F FSL R+++ + + N+ FSP
Sbjct: 20 PVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLYRQLAHQSNSTNIFFSPV 79
Query: 104 GMSLAMTGLMLGATGPTETQIKRGLHLQALKPTKPGLLPSLFKGLRETLSRNLELGLTQG 163
++ A L LG T +I GL+ + + + + LR + +L LT G
Sbjct: 80 SIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTG 139
Query: 164 SFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRNASQAKRLMNHYINKETRGKIPKLFDE 223
+ F+ + + + F K+ + +E +NF + +AK+ +N Y+ K T+GKI L E
Sbjct: 140 NGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKE 199
Query: 224 INPETKLILVDYILFKGKWLTPFDPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNF 283
++ +T LV+YI FKGKW PF+ TE + FH+D+ T+KVPMM G F K
Sbjct: 200 LDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKL 259
Query: 284 RCHVLKLPYQGNATMLVVLMEKMGDHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLD 343
VL + Y GNAT + L ++ G LE+ LT D++ +L N R+ + PK +
Sbjct: 260 SSWVLLMKYLGNATAIFFLPDE-GKLQHLENELTHDIITKFLENEDRRSASLHLPKLSIT 318
Query: 344 QKYEMHELLRQMGIRRIFSPFADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILS 403
Y++ +L Q+GI ++FS ADLS ++ L++S+ + + V+ +DE+GTEA +
Sbjct: 319 GTYDLKSVLGQLGITKVFSNGADLSGVTEEA-PLKLSKAVHKAVLTIDEKGTEAAGAMFL 377
Query: 404 EITAYSMPPVIKVDRPFHFMIYEETSGMLLFLGRVVNPT 442
E S+PP +K ++PF F++ E+ + LF+G+VVNPT
Sbjct: 378 EAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNPT 416
>gi|189163540 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 213 bits (543), Expect = 2e-55
Identities = 127/399 (31%), Positives = 211/399 (52%), Gaps = 3/399 (0%)
Query: 45 PKEEEEDEQEASEEKASEEEKAWLMASRQQLAKETSNFGFSLLRKISMRHDG-NMVFSPF 103
P ED Q + +K + ++ + F FSL R+++ + + N+ FSP
Sbjct: 20 PVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLYRQLAHQSNSTNIFFSPV 79
Query: 104 GMSLAMTGLMLGATGPTETQIKRGLHLQALKPTKPGLLPSLFKGLRETLSRNLELGLTQG 163
++ A L LG T +I GL+ + + + + LR + +L LT G
Sbjct: 80 SIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTG 139
Query: 164 SFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRNASQAKRLMNHYINKETRGKIPKLFDE 223
+ F+ + + + F K+ + +E +NF + +AK+ +N Y+ K T+GKI L E
Sbjct: 140 NGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKE 199
Query: 224 INPETKLILVDYILFKGKWLTPFDPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNF 283
++ +T LV+YI FKGKW PF+ TE + FH+D+ T+KVPMM G F K
Sbjct: 200 LDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKL 259
Query: 284 RCHVLKLPYQGNATMLVVLMEKMGDHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLD 343
VL + Y GNAT + L ++ G LE+ LT D++ +L N R+ + PK +
Sbjct: 260 SSWVLLMKYLGNATAIFFLPDE-GKLQHLENELTHDIITKFLENEDRRSASLHLPKLSIT 318
Query: 344 QKYEMHELLRQMGIRRIFSPFADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILS 403
Y++ +L Q+GI ++FS ADLS ++ L++S+ + + V+ +DE+GTEA +
Sbjct: 319 GTYDLKSVLGQLGITKVFSNGADLSGVTEEA-PLKLSKAVHKAVLTIDEKGTEAAGAMFL 377
Query: 404 EITAYSMPPVIKVDRPFHFMIYEETSGMLLFLGRVVNPT 442
E S+PP +K ++PF F++ E+ + LF+G+VVNPT
Sbjct: 378 EAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNPT 416
>gi|189163538 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 213 bits (543), Expect = 2e-55
Identities = 127/399 (31%), Positives = 211/399 (52%), Gaps = 3/399 (0%)
Query: 45 PKEEEEDEQEASEEKASEEEKAWLMASRQQLAKETSNFGFSLLRKISMRHDG-NMVFSPF 103
P ED Q + +K + ++ + F FSL R+++ + + N+ FSP
Sbjct: 20 PVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLYRQLAHQSNSTNIFFSPV 79
Query: 104 GMSLAMTGLMLGATGPTETQIKRGLHLQALKPTKPGLLPSLFKGLRETLSRNLELGLTQG 163
++ A L LG T +I GL+ + + + + LR + +L LT G
Sbjct: 80 SIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTG 139
Query: 164 SFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRNASQAKRLMNHYINKETRGKIPKLFDE 223
+ F+ + + + F K+ + +E +NF + +AK+ +N Y+ K T+GKI L E
Sbjct: 140 NGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKE 199
Query: 224 INPETKLILVDYILFKGKWLTPFDPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNF 283
++ +T LV+YI FKGKW PF+ TE + FH+D+ T+KVPMM G F K
Sbjct: 200 LDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKL 259
Query: 284 RCHVLKLPYQGNATMLVVLMEKMGDHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLD 343
VL + Y GNAT + L ++ G LE+ LT D++ +L N R+ + PK +
Sbjct: 260 SSWVLLMKYLGNATAIFFLPDE-GKLQHLENELTHDIITKFLENEDRRSASLHLPKLSIT 318
Query: 344 QKYEMHELLRQMGIRRIFSPFADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILS 403
Y++ +L Q+GI ++FS ADLS ++ L++S+ + + V+ +DE+GTEA +
Sbjct: 319 GTYDLKSVLGQLGITKVFSNGADLSGVTEEA-PLKLSKAVHKAVLTIDEKGTEAAGAMFL 377
Query: 404 EITAYSMPPVIKVDRPFHFMIYEETSGMLLFLGRVVNPT 442
E S+PP +K ++PF F++ E+ + LF+G+VVNPT
Sbjct: 378 EAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNPT 416
>gi|189163536 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 213 bits (543), Expect = 2e-55
Identities = 127/399 (31%), Positives = 211/399 (52%), Gaps = 3/399 (0%)
Query: 45 PKEEEEDEQEASEEKASEEEKAWLMASRQQLAKETSNFGFSLLRKISMRHDG-NMVFSPF 103
P ED Q + +K + ++ + F FSL R+++ + + N+ FSP
Sbjct: 20 PVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLYRQLAHQSNSTNIFFSPV 79
Query: 104 GMSLAMTGLMLGATGPTETQIKRGLHLQALKPTKPGLLPSLFKGLRETLSRNLELGLTQG 163
++ A L LG T +I GL+ + + + + LR + +L LT G
Sbjct: 80 SIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTG 139
Query: 164 SFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRNASQAKRLMNHYINKETRGKIPKLFDE 223
+ F+ + + + F K+ + +E +NF + +AK+ +N Y+ K T+GKI L E
Sbjct: 140 NGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKE 199
Query: 224 INPETKLILVDYILFKGKWLTPFDPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNF 283
++ +T LV+YI FKGKW PF+ TE + FH+D+ T+KVPMM G F K
Sbjct: 200 LDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKL 259
Query: 284 RCHVLKLPYQGNATMLVVLMEKMGDHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLD 343
VL + Y GNAT + L ++ G LE+ LT D++ +L N R+ + PK +
Sbjct: 260 SSWVLLMKYLGNATAIFFLPDE-GKLQHLENELTHDIITKFLENEDRRSASLHLPKLSIT 318
Query: 344 QKYEMHELLRQMGIRRIFSPFADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILS 403
Y++ +L Q+GI ++FS ADLS ++ L++S+ + + V+ +DE+GTEA +
Sbjct: 319 GTYDLKSVLGQLGITKVFSNGADLSGVTEEA-PLKLSKAVHKAVLTIDEKGTEAAGAMFL 377
Query: 404 EITAYSMPPVIKVDRPFHFMIYEETSGMLLFLGRVVNPT 442
E S+PP +K ++PF F++ E+ + LF+G+VVNPT
Sbjct: 378 EAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNPT 416
>gi|189163534 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 213 bits (543), Expect = 2e-55
Identities = 127/399 (31%), Positives = 211/399 (52%), Gaps = 3/399 (0%)
Query: 45 PKEEEEDEQEASEEKASEEEKAWLMASRQQLAKETSNFGFSLLRKISMRHDG-NMVFSPF 103
P ED Q + +K + ++ + F FSL R+++ + + N+ FSP
Sbjct: 20 PVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLYRQLAHQSNSTNIFFSPV 79
Query: 104 GMSLAMTGLMLGATGPTETQIKRGLHLQALKPTKPGLLPSLFKGLRETLSRNLELGLTQG 163
++ A L LG T +I GL+ + + + + LR + +L LT G
Sbjct: 80 SIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTG 139
Query: 164 SFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRNASQAKRLMNHYINKETRGKIPKLFDE 223
+ F+ + + + F K+ + +E +NF + +AK+ +N Y+ K T+GKI L E
Sbjct: 140 NGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKE 199
Query: 224 INPETKLILVDYILFKGKWLTPFDPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNF 283
++ +T LV+YI FKGKW PF+ TE + FH+D+ T+KVPMM G F K
Sbjct: 200 LDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKL 259
Query: 284 RCHVLKLPYQGNATMLVVLMEKMGDHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLD 343
VL + Y GNAT + L ++ G LE+ LT D++ +L N R+ + PK +
Sbjct: 260 SSWVLLMKYLGNATAIFFLPDE-GKLQHLENELTHDIITKFLENEDRRSASLHLPKLSIT 318
Query: 344 QKYEMHELLRQMGIRRIFSPFADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILS 403
Y++ +L Q+GI ++FS ADLS ++ L++S+ + + V+ +DE+GTEA +
Sbjct: 319 GTYDLKSVLGQLGITKVFSNGADLSGVTEEA-PLKLSKAVHKAVLTIDEKGTEAAGAMFL 377
Query: 404 EITAYSMPPVIKVDRPFHFMIYEETSGMLLFLGRVVNPT 442
E S+PP +K ++PF F++ E+ + LF+G+VVNPT
Sbjct: 378 EAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNPT 416
>gi|189163532 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 213 bits (543), Expect = 2e-55
Identities = 127/399 (31%), Positives = 211/399 (52%), Gaps = 3/399 (0%)
Query: 45 PKEEEEDEQEASEEKASEEEKAWLMASRQQLAKETSNFGFSLLRKISMRHDG-NMVFSPF 103
P ED Q + +K + ++ + F FSL R+++ + + N+ FSP
Sbjct: 20 PVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLYRQLAHQSNSTNIFFSPV 79
Query: 104 GMSLAMTGLMLGATGPTETQIKRGLHLQALKPTKPGLLPSLFKGLRETLSRNLELGLTQG 163
++ A L LG T +I GL+ + + + + LR + +L LT G
Sbjct: 80 SIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTG 139
Query: 164 SFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRNASQAKRLMNHYINKETRGKIPKLFDE 223
+ F+ + + + F K+ + +E +NF + +AK+ +N Y+ K T+GKI L E
Sbjct: 140 NGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKE 199
Query: 224 INPETKLILVDYILFKGKWLTPFDPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNF 283
++ +T LV+YI FKGKW PF+ TE + FH+D+ T+KVPMM G F K
Sbjct: 200 LDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKL 259
Query: 284 RCHVLKLPYQGNATMLVVLMEKMGDHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLD 343
VL + Y GNAT + L ++ G LE+ LT D++ +L N R+ + PK +
Sbjct: 260 SSWVLLMKYLGNATAIFFLPDE-GKLQHLENELTHDIITKFLENEDRRSASLHLPKLSIT 318
Query: 344 QKYEMHELLRQMGIRRIFSPFADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILS 403
Y++ +L Q+GI ++FS ADLS ++ L++S+ + + V+ +DE+GTEA +
Sbjct: 319 GTYDLKSVLGQLGITKVFSNGADLSGVTEEA-PLKLSKAVHKAVLTIDEKGTEAAGAMFL 377
Query: 404 EITAYSMPPVIKVDRPFHFMIYEETSGMLLFLGRVVNPT 442
E S+PP +K ++PF F++ E+ + LF+G+VVNPT
Sbjct: 378 EAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNPT 416
>gi|189163530 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 213 bits (543), Expect = 2e-55
Identities = 127/399 (31%), Positives = 211/399 (52%), Gaps = 3/399 (0%)
Query: 45 PKEEEEDEQEASEEKASEEEKAWLMASRQQLAKETSNFGFSLLRKISMRHDG-NMVFSPF 103
P ED Q + +K + ++ + F FSL R+++ + + N+ FSP
Sbjct: 20 PVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLYRQLAHQSNSTNIFFSPV 79
Query: 104 GMSLAMTGLMLGATGPTETQIKRGLHLQALKPTKPGLLPSLFKGLRETLSRNLELGLTQG 163
++ A L LG T +I GL+ + + + + LR + +L LT G
Sbjct: 80 SIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTG 139
Query: 164 SFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRNASQAKRLMNHYINKETRGKIPKLFDE 223
+ F+ + + + F K+ + +E +NF + +AK+ +N Y+ K T+GKI L E
Sbjct: 140 NGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKE 199
Query: 224 INPETKLILVDYILFKGKWLTPFDPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNF 283
++ +T LV+YI FKGKW PF+ TE + FH+D+ T+KVPMM G F K
Sbjct: 200 LDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKL 259
Query: 284 RCHVLKLPYQGNATMLVVLMEKMGDHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLD 343
VL + Y GNAT + L ++ G LE+ LT D++ +L N R+ + PK +
Sbjct: 260 SSWVLLMKYLGNATAIFFLPDE-GKLQHLENELTHDIITKFLENEDRRSASLHLPKLSIT 318
Query: 344 QKYEMHELLRQMGIRRIFSPFADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILS 403
Y++ +L Q+GI ++FS ADLS ++ L++S+ + + V+ +DE+GTEA +
Sbjct: 319 GTYDLKSVLGQLGITKVFSNGADLSGVTEEA-PLKLSKAVHKAVLTIDEKGTEAAGAMFL 377
Query: 404 EITAYSMPPVIKVDRPFHFMIYEETSGMLLFLGRVVNPT 442
E S+PP +K ++PF F++ E+ + LF+G+VVNPT
Sbjct: 378 EAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNPT 416
>gi|189163528 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 213 bits (543), Expect = 2e-55
Identities = 127/399 (31%), Positives = 211/399 (52%), Gaps = 3/399 (0%)
Query: 45 PKEEEEDEQEASEEKASEEEKAWLMASRQQLAKETSNFGFSLLRKISMRHDG-NMVFSPF 103
P ED Q + +K + ++ + F FSL R+++ + + N+ FSP
Sbjct: 20 PVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLYRQLAHQSNSTNIFFSPV 79
Query: 104 GMSLAMTGLMLGATGPTETQIKRGLHLQALKPTKPGLLPSLFKGLRETLSRNLELGLTQG 163
++ A L LG T +I GL+ + + + + LR + +L LT G
Sbjct: 80 SIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTG 139
Query: 164 SFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRNASQAKRLMNHYINKETRGKIPKLFDE 223
+ F+ + + + F K+ + +E +NF + +AK+ +N Y+ K T+GKI L E
Sbjct: 140 NGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKE 199
Query: 224 INPETKLILVDYILFKGKWLTPFDPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNF 283
++ +T LV+YI FKGKW PF+ TE + FH+D+ T+KVPMM G F K
Sbjct: 200 LDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKL 259
Query: 284 RCHVLKLPYQGNATMLVVLMEKMGDHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLD 343
VL + Y GNAT + L ++ G LE+ LT D++ +L N R+ + PK +
Sbjct: 260 SSWVLLMKYLGNATAIFFLPDE-GKLQHLENELTHDIITKFLENEDRRSASLHLPKLSIT 318
Query: 344 QKYEMHELLRQMGIRRIFSPFADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILS 403
Y++ +L Q+GI ++FS ADLS ++ L++S+ + + V+ +DE+GTEA +
Sbjct: 319 GTYDLKSVLGQLGITKVFSNGADLSGVTEEA-PLKLSKAVHKAVLTIDEKGTEAAGAMFL 377
Query: 404 EITAYSMPPVIKVDRPFHFMIYEETSGMLLFLGRVVNPT 442
E S+PP +K ++PF F++ E+ + LF+G+VVNPT
Sbjct: 378 EAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNPT 416
>gi|50363219 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 213 bits (543), Expect = 2e-55
Identities = 127/399 (31%), Positives = 211/399 (52%), Gaps = 3/399 (0%)
Query: 45 PKEEEEDEQEASEEKASEEEKAWLMASRQQLAKETSNFGFSLLRKISMRHDG-NMVFSPF 103
P ED Q + +K + ++ + F FSL R+++ + + N+ FSP
Sbjct: 20 PVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLYRQLAHQSNSTNIFFSPV 79
Query: 104 GMSLAMTGLMLGATGPTETQIKRGLHLQALKPTKPGLLPSLFKGLRETLSRNLELGLTQG 163
++ A L LG T +I GL+ + + + + LR + +L LT G
Sbjct: 80 SIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTG 139
Query: 164 SFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRNASQAKRLMNHYINKETRGKIPKLFDE 223
+ F+ + + + F K+ + +E +NF + +AK+ +N Y+ K T+GKI L E
Sbjct: 140 NGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKE 199
Query: 224 INPETKLILVDYILFKGKWLTPFDPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNF 283
++ +T LV+YI FKGKW PF+ TE + FH+D+ T+KVPMM G F K
Sbjct: 200 LDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKL 259
Query: 284 RCHVLKLPYQGNATMLVVLMEKMGDHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLD 343
VL + Y GNAT + L ++ G LE+ LT D++ +L N R+ + PK +
Sbjct: 260 SSWVLLMKYLGNATAIFFLPDE-GKLQHLENELTHDIITKFLENEDRRSASLHLPKLSIT 318
Query: 344 QKYEMHELLRQMGIRRIFSPFADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILS 403
Y++ +L Q+GI ++FS ADLS ++ L++S+ + + V+ +DE+GTEA +
Sbjct: 319 GTYDLKSVLGQLGITKVFSNGADLSGVTEEA-PLKLSKAVHKAVLTIDEKGTEAAGAMFL 377
Query: 404 EITAYSMPPVIKVDRPFHFMIYEETSGMLLFLGRVVNPT 442
E S+PP +K ++PF F++ E+ + LF+G+VVNPT
Sbjct: 378 EAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNPT 416
>gi|50363221 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 213 bits (543), Expect = 2e-55
Identities = 127/399 (31%), Positives = 211/399 (52%), Gaps = 3/399 (0%)
Query: 45 PKEEEEDEQEASEEKASEEEKAWLMASRQQLAKETSNFGFSLLRKISMRHDG-NMVFSPF 103
P ED Q + +K + ++ + F FSL R+++ + + N+ FSP
Sbjct: 20 PVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLYRQLAHQSNSTNIFFSPV 79
Query: 104 GMSLAMTGLMLGATGPTETQIKRGLHLQALKPTKPGLLPSLFKGLRETLSRNLELGLTQG 163
++ A L LG T +I GL+ + + + + LR + +L LT G
Sbjct: 80 SIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTG 139
Query: 164 SFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRNASQAKRLMNHYINKETRGKIPKLFDE 223
+ F+ + + + F K+ + +E +NF + +AK+ +N Y+ K T+GKI L E
Sbjct: 140 NGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKE 199
Query: 224 INPETKLILVDYILFKGKWLTPFDPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNF 283
++ +T LV+YI FKGKW PF+ TE + FH+D+ T+KVPMM G F K
Sbjct: 200 LDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKL 259
Query: 284 RCHVLKLPYQGNATMLVVLMEKMGDHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLD 343
VL + Y GNAT + L ++ G LE+ LT D++ +L N R+ + PK +
Sbjct: 260 SSWVLLMKYLGNATAIFFLPDE-GKLQHLENELTHDIITKFLENEDRRSASLHLPKLSIT 318
Query: 344 QKYEMHELLRQMGIRRIFSPFADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILS 403
Y++ +L Q+GI ++FS ADLS ++ L++S+ + + V+ +DE+GTEA +
Sbjct: 319 GTYDLKSVLGQLGITKVFSNGADLSGVTEEA-PLKLSKAVHKAVLTIDEKGTEAAGAMFL 377
Query: 404 EITAYSMPPVIKVDRPFHFMIYEETSGMLLFLGRVVNPT 442
E S+PP +K ++PF F++ E+ + LF+G+VVNPT
Sbjct: 378 EAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNPT 416
>gi|50363217 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 213 bits (543), Expect = 2e-55
Identities = 127/399 (31%), Positives = 211/399 (52%), Gaps = 3/399 (0%)
Query: 45 PKEEEEDEQEASEEKASEEEKAWLMASRQQLAKETSNFGFSLLRKISMRHDG-NMVFSPF 103
P ED Q + +K + ++ + F FSL R+++ + + N+ FSP
Sbjct: 20 PVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLYRQLAHQSNSTNIFFSPV 79
Query: 104 GMSLAMTGLMLGATGPTETQIKRGLHLQALKPTKPGLLPSLFKGLRETLSRNLELGLTQG 163
++ A L LG T +I GL+ + + + + LR + +L LT G
Sbjct: 80 SIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTG 139
Query: 164 SFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRNASQAKRLMNHYINKETRGKIPKLFDE 223
+ F+ + + + F K+ + +E +NF + +AK+ +N Y+ K T+GKI L E
Sbjct: 140 NGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKE 199
Query: 224 INPETKLILVDYILFKGKWLTPFDPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNF 283
++ +T LV+YI FKGKW PF+ TE + FH+D+ T+KVPMM G F K
Sbjct: 200 LDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKL 259
Query: 284 RCHVLKLPYQGNATMLVVLMEKMGDHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLD 343
VL + Y GNAT + L ++ G LE+ LT D++ +L N R+ + PK +
Sbjct: 260 SSWVLLMKYLGNATAIFFLPDE-GKLQHLENELTHDIITKFLENEDRRSASLHLPKLSIT 318
Query: 344 QKYEMHELLRQMGIRRIFSPFADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILS 403
Y++ +L Q+GI ++FS ADLS ++ L++S+ + + V+ +DE+GTEA +
Sbjct: 319 GTYDLKSVLGQLGITKVFSNGADLSGVTEEA-PLKLSKAVHKAVLTIDEKGTEAAGAMFL 377
Query: 404 EITAYSMPPVIKVDRPFHFMIYEETSGMLLFLGRVVNPT 442
E S+PP +K ++PF F++ E+ + LF+G+VVNPT
Sbjct: 378 EAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNPT 416
>gi|50659080 serpin peptidase inhibitor, clade A, member 3 precursor
[Homo sapiens]
Length = 423
Score = 202 bits (514), Expect = 5e-52
Identities = 127/377 (33%), Positives = 212/377 (56%), Gaps = 15/377 (3%)
Query: 75 LAKETSNFGFSLLRKISMRH-DGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQAL 133
LA +F FSL +++ ++ D N++FSP +S A+ L LGA T T+I +GL L
Sbjct: 49 LASANVDFAFSLYKQLVLKAPDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFN-L 107
Query: 134 KPTKPGLLPSLFKGLRETLSRNL-ELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVP 192
T + F+ L TL+++ EL L+ G+ F+ + + + F +KR + +E
Sbjct: 108 TETSEAEIHQSFQHLLRTLNQSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFA 167
Query: 193 MNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPVFTE 252
+F++++ AK+L+N Y+ TRGKI L +++ +T ++LV+YI FK KW PFDP T
Sbjct: 168 TDFQDSAAAKKLINDYVKNGTRGKITDLIKDLDSQTMMVLVNYIFFKAKWEMPFDPQDTH 227
Query: 253 VDTFHLDKYKTIKVPMMYGAGKFASTF-DKNFRCHVLKLPYQGNATMLVVL--MEKMGDH 309
F+L K K + VPMM F D+ C V++L Y GNA+ L +L +KM +
Sbjct: 228 QSRFYLSKKKWVMVPMMSLHHLTIPYFRDEELSCTVVELKYTGNASALFILPDQDKMEE- 286
Query: 310 LALEDYLTTDLVETWLRNMKTRNM-EVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLS 368
+E L + ++ W +++ R + E++ PKF + + Y ++++L Q+GI F+ ADLS
Sbjct: 287 --VEAMLLPETLKRWRDSLEFREIGELYLPKFSISRDYNLNDILLQLGIEEAFTSKADLS 344
Query: 369 ELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYS----MPPVIKVDRPFHFMI 424
++ RNL VS+V+ + V++V E GTEA A +IT S +++ +RPF +I
Sbjct: 345 GITG-ARNLAVSQVVHKAVLDVFEEGTEASAATAVKITLLSALVETRTIVRFNRPFLMII 403
Query: 425 YEETSGMLLFLGRVVNP 441
+ + F+ +V NP
Sbjct: 404 VPTDTQNIFFMSKVTNP 420
>gi|194018472 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 5 [Homo
sapiens]
Length = 406
Score = 190 bits (483), Expect = 2e-48
Identities = 118/365 (32%), Positives = 195/365 (53%), Gaps = 9/365 (2%)
Query: 81 NFGFSLLRKI-SMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQALKPTKPG 139
+F F L R + S ++ FSP +S+++ L LGA T+ QI GL L K ++
Sbjct: 47 DFTFDLYRALASAAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSEKE 106
Query: 140 LLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRNAS 199
L + L+E L+ G+ F D+++TF + K + + P NFR+++
Sbjct: 107 LHRGFQQLLQELNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNFRDSA 166
Query: 200 QAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPVFTEVDTFHLD 259
A + +N Y+ K+T+GKI L ++ +I+V+YI FK KW T F+ T+ F++
Sbjct: 167 GAMKQINDYVAKQTKGKIVDLLKNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDFYVT 226
Query: 260 KYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHLALEDYLTTD 319
++VPMM ++ D+N C V+ +PYQGNAT L +L + G +E+ L+
Sbjct: 227 SETVVRVPMMSREDQYHYLLDRNLSCRVVGVPYQGNATALFILPSE-GKMQQVENGLSEK 285
Query: 320 LVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSATGRNLQV 379
+ WL+ K R +E++ PKF ++ Y++ ++L +GI +F+ ADLS +S N+QV
Sbjct: 286 TLRKWLKMFKKRQLELYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLSGIS-NHSNIQV 344
Query: 380 SRVLQRTVIEVDERGTEAVAG---ILSEITAYSMPPVIKVDRPFHFMIYEETSGMLLFLG 436
S ++ + V+EVDE GT A A I + +A + +RPF I + +LFLG
Sbjct: 345 SEMVHKAVVEVDESGTRAAAATGTIFTFRSARLNSQRLVFNRPFLMFIVDNN---ILFLG 401
Query: 437 RVVNP 441
+V P
Sbjct: 402 KVNRP 406
>gi|205277441 serine (or cysteine) proteinase inhibitor, clade A,
member 7 [Homo sapiens]
Length = 415
Score = 189 bits (480), Expect = 4e-48
Identities = 125/382 (32%), Positives = 205/382 (53%), Gaps = 14/382 (3%)
Query: 70 ASRQQLAKETSNFGFSLLRKISMRH-DGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGL 128
A+ +++ ++F F+L R+ ++ D N+ FSP +S A+ L GA T+T+I L
Sbjct: 37 ATLYKMSSINADFAFNLYRRFTVETPDKNIFFSPVSISAALVMLSFGACCSTQTEIVETL 96
Query: 129 HLQALKPTKPGLLPSLFKGLRETLS-RNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFD 187
L T + F+ L +L+ EL L G+ FI K F N K ++
Sbjct: 97 GFN-LTDTPMVEIQHGFQHLICSLNFPKKELELQIGNALFIGKHLKPLAKFLNDVKTLYE 155
Query: 188 TECVPMNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFD 247
TE +F N S AK+ +N ++ +T+GK+ L ++ P T ++LV+YI FK +W PFD
Sbjct: 156 TEVFSTDFSNISAAKQEINSHVEMQTKGKVVGLIQDLKPNTIMVLVNYIHFKAQWANPFD 215
Query: 248 PVFTE-VDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKM 306
P TE +F +DK T++VPMM+ ++ D C VL++ Y NA L VL K
Sbjct: 216 PSKTEDSSSFLIDKTTTVQVPMMHQMEQYYHLVDMELNCTVLQMDYSKNALALFVL-PKE 274
Query: 307 GDHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFAD 366
G ++E +++ ++ W R ++ +++F PKF + Y++ L +MGI+ +S AD
Sbjct: 275 GQMESVEAAMSSKTLKKWNRLLQKGWVDLFVPKFSISATYDLGATLLKMGIQHAYSENAD 334
Query: 367 LSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMP------PVIKVDRPF 420
S L+ L++S + V+ + E+GTEA A + E+ P P+I++DR F
Sbjct: 335 FSGLT-EDNGLKLSNAAHKAVLHIGEKGTEAAA--VPEVELSDQPENTFLHPIIQIDRSF 391
Query: 421 HFMIYEETSGMLLFLGRVVNPT 442
+I E ++ +LFLG+VVNPT
Sbjct: 392 MLLILERSTRSILFLGKVVNPT 413
>gi|110225347 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 9 isoform
A [Homo sapiens]
Length = 435
Score = 186 bits (473), Expect = 3e-47
Identities = 120/376 (31%), Positives = 197/376 (52%), Gaps = 10/376 (2%)
Query: 74 QLAKETSNFGFSLLRKISMRHDG-NMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQA 132
Q+ ++F F L R++ + N+ FSP +S ++ L LGA T+TQI +GL
Sbjct: 61 QVYSLNTDFAFRLYRRLVLETPSQNIFFSPVSVSTSLAMLSLGAHSVTKTQILQGLGFN- 119
Query: 133 LKPTKPGLLPSLFKGLRETLS-RNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECV 191
L T + F+ L +L+ + +L L GS F+ K+ ++ F KR ++ E
Sbjct: 120 LTHTPESAIHQGFQHLVHSLTVPSKDLTLKMGSALFVKKELQLQANFLGNVKRLYEAEVF 179
Query: 192 PMNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPVFT 251
+F N S A+ +N ++ K+T+GK+ + ++ T ++LV++I FK KW PF P +T
Sbjct: 180 STDFSNPSIAQARINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYT 239
Query: 252 EVD-TFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHL 310
+ F + + T+ VPMM+ +FA D C VL++ Y+G+A VL K G
Sbjct: 240 RKNFPFLVGEQVTVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSK-GKMR 298
Query: 311 ALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSEL 370
LE L+ + W +++ R +EVF P+F + Y + +L +MGI+ +F AD S +
Sbjct: 299 QLEQALSARTLRKWSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGI 358
Query: 371 SATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPP----VIKVDRPFHFMIYE 426
A +LQVS+ + V++V E GTEA A ++ S + +R F MI
Sbjct: 359 -AKRDSLQVSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITN 417
Query: 427 ETSGMLLFLGRVVNPT 442
+ + +LFLG+V NPT
Sbjct: 418 KATDGILFLGKVENPT 433
>gi|73858564 corticosteroid binding globulin precursor [Homo
sapiens]
Length = 405
Score = 186 bits (471), Expect = 5e-47
Identities = 104/369 (28%), Positives = 199/369 (53%), Gaps = 5/369 (1%)
Query: 75 LAKETSNFGFSLLRK-ISMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQAL 133
LA +F FSL + +++ N+ SP +S+A+ L LG G T Q+ +GL
Sbjct: 39 LASANVDFAFSLYKHLVALSPKKNIFISPVSISMALAMLSLGTCGHTRAQLLQGLGFNLT 98
Query: 134 KPTKPGLLPSLFKGLRETLSRN-LELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVP 192
+ ++ + F+ L + +++ L +T G+ F+ ++ E+F K Y+++E +
Sbjct: 99 ERSETEIHQG-FQHLHQLFAKSDTSLEMTMGNALFLDGSLELLESFSADIKHYYESEVLA 157
Query: 193 MNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPVFTE 252
MNF++ + A R +N Y+ +T+GKI LF ++ L+LV+YI FKG W PFD T
Sbjct: 158 MNFQDWATASRQINSYVKNKTQGKIVDLFSGLDSPAILVLVNYIFFKGTWTQPFDLASTR 217
Query: 253 VDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHLAL 312
+ F++D+ +KVPMM + + D C ++++ Y GN T+ +L +K G +
Sbjct: 218 EENFYVDETTVVKVPMMLQSSTISYLHDAELPCQLVQMNYVGNGTVFFILPDK-GKMNTV 276
Query: 313 EDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSA 372
L+ D + W + + ++++ PK + Y++ ++L +MGI +F+ A+ S ++
Sbjct: 277 IAALSRDTINRWSAGLTSSQVDLYIPKVTISGVYDLGDVLEEMGIADLFTNQANFSRITQ 336
Query: 373 TGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVDRPFHFMIYEETSGML 432
+ L+ S+V+ + V++++E G + + S P +++ ++PF MI++ +
Sbjct: 337 DAQ-LKSSKVVHKAVLQLNEEGVDTAGSTGVTLNLTSKPIILRFNQPFIIMIFDHFTWSS 395
Query: 433 LFLGRVVNP 441
LFL RV+NP
Sbjct: 396 LFLARVMNP 404
>gi|73858566 heparin cofactor II precursor [Homo sapiens]
Length = 499
Score = 181 bits (460), Expect = 9e-46
Identities = 120/377 (31%), Positives = 186/377 (49%), Gaps = 10/377 (2%)
Query: 73 QQLAKETSNFGFSLLR--KISMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHL 130
Q+L + F F+L R K + N+ +P G+S AM + LG G T Q+ LH
Sbjct: 124 QRLNILNAKFAFNLYRVLKDQVNTFDNIFIAPVGISTAMGMISLGLKGETHEQVHSILHF 183
Query: 131 Q----ALKPTKPGLLPSLFKGLRETL-SRNLELGLTQGSFAFIHKDFDVKETFFNLSKRY 185
+ A + + +LF+ L L RN L + +I K F + F + Y
Sbjct: 184 KDFVNASSKYEITTIHNLFRKLTHRLFRRNFGYTLRSVNDLYIQKQFPILLDFKTKVREY 243
Query: 186 FDTECVPMNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTP 245
+ E +F + + + NH I K T+G I + I+P T++++++ I FKG W+
Sbjct: 244 YFAEAQIADFSDPAFISKTNNH-IMKLTKGLIKDALENIDPATQMMILNCIYFKGSWVNK 302
Query: 246 FDPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEK 305
F T F L++ + +KV MM G F + D+ C +L+L Y G +ML+V+ K
Sbjct: 303 FPVEMTHNHNFRLNEREVVKVSMMQTKGNFLAANDQELDCDILQLEYVGGISMLIVVPHK 362
Query: 306 MGDHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFA 365
M LE LT +VE W ++M R EV PKFKL++ Y + E L+ MGIR +F
Sbjct: 363 MSGMKTLEAQLTPRVVERWQKSMTNRTREVLLPKFKLEKNYNLVESLKLMGIRMLFDKNG 422
Query: 366 DLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVDRPFHFMIY 425
+++ +S + + + + I V+E GT+A S VDRPF F+IY
Sbjct: 423 NMAGIS--DQRIAIDLFKHQGTITVNEEGTQATTVTTVGFMPLSTQVRFTVDRPFLFLIY 480
Query: 426 EETSGMLLFLGRVVNPT 442
E + LLF+GRV NP+
Sbjct: 481 EHRTSCLLFMGRVANPS 497
>gi|5453886 serpin peptidase inhibitor, clade I (pancpin), member 2
[Homo sapiens]
Length = 405
Score = 169 bits (427), Expect = 6e-42
Identities = 105/374 (28%), Positives = 193/374 (51%), Gaps = 12/374 (3%)
Query: 76 AKETSNFGFSLLRKISMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQALKP 135
A++ + F L +++S+ H N++FSP G++L + + LGA G + QI++ L Q
Sbjct: 23 AQKNTEFAVDLYQEVSLSHKDNIIFSPLGITLVLEMVQLGAKGKAQQQIRQTLKQQETSA 82
Query: 136 TKPG-LLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMN 194
+ +L S F + E + E + ++ + F VKE + + +K +F + ++
Sbjct: 83 GEEFFVLKSFFSAISE---KKQEFTFNLANALYLQEGFTVKEQYLHGNKEFFQSAIKLVD 139
Query: 195 FRNASQAKRLMNHYINKETRGKIPKLF--DEINPETKLILVDYILFKGKWLTPFDPVFTE 252
F++A +++ ++ ++T GKI +F +E P T+L+LV+ I FKG W F T+
Sbjct: 140 FQDAKACAEMISTWVERKTDGKIKDMFSGEEFGPLTRLVLVNAIYFKGDWKQKFRKEDTQ 199
Query: 253 VDTFHLDKYKTIKVPMMYGA--GKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKMG-DH 309
+ F T+K+PMM K+ + + VL+L Y+G+ L++++ G D
Sbjct: 200 LINFTKKNGSTVKIPMMKALLRTKYGYFSESSLNYQVLELSYKGDEFSLIIILPAEGMDI 259
Query: 310 LALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSE 369
+E +T + WL M+ +E+ P+FK++QK + ++L + I IFS DLS
Sbjct: 260 EEVEKLITAQQILKWLSEMQEEEVEISLPRFKVEQKVDFKDVLYSLNITEIFSGGCDLSG 319
Query: 370 LSATGRNLQVSRVLQRTVIEVDERGTEAV--AGILSEITAYSMPPVIKVDRPFHFMIYEE 427
++ + + VS+V Q+ E++E G+EA GI + + PF F++
Sbjct: 320 ITDSS-EVYVSQVTQKVFFEINEDGSEAATSTGIHIPVIMSLAQSQFIANHPFLFIMKHN 378
Query: 428 TSGMLLFLGRVVNP 441
+ +LF+GRV NP
Sbjct: 379 PTESILFMGRVTNP 392
>gi|13489087 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 1 [Homo sapiens]
Length = 379
Score = 167 bits (423), Expect = 2e-41
Identities = 114/384 (29%), Positives = 197/384 (51%), Gaps = 21/384 (5%)
Query: 73 QQLAKETSNFGFSLLRKISMRHD-GNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQ 131
+QL+ + F L +S + GN+ SPF +S AM + LG G T Q+ + H
Sbjct: 2 EQLSSANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHFN 61
Query: 132 ALKPTKPGLLPSLFKGLRETLS-RNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTEC 190
++ S F+ L ++ R L + + K ++ F +++ + +
Sbjct: 62 TVEEVH-----SRFQSLNADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQKTYGADL 116
Query: 191 VPMNFRNASQ-AKRLMNHYINKETRGKIPKLFDE--INPETKLILVDYILFKGKWLTPFD 247
++F++AS+ A++ +N ++ +T GKIP+L ++ TKL+LV+ I FKG W F
Sbjct: 117 ASVDFQHASEDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFKGNWKDKFM 176
Query: 248 PVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLM---- 303
T F L+K V MMY KFA + ++ +C VL+LPYQG +V+L+
Sbjct: 177 KEATTNAPFRLNKKDRKTVKMMYQKKKFAYGYIEDLKCRVLELPYQGEELSMVILLPDDI 236
Query: 304 -EKMGDHLALEDYLTTDLVETWLR--NMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRI 360
++ +E+ LT + + W + N+ + V P+FKL++ Y ++ L ++G++ +
Sbjct: 237 EDESTGLKKIEEQLTLEKLHEWTKPENLDFIEVNVSLPRFKLEESYTLNSDLARLGVQDL 296
Query: 361 F-SPFADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPV--IKVD 417
F S ADLS +S R++ +S+++ ++ +EV+E GTEA A T + P D
Sbjct: 297 FNSSKADLSGMSG-ARDIFISKIVHKSFVEVNEEGTEAAAATAGIATFCMLMPEENFTAD 355
Query: 418 RPFHFMIYEETSGMLLFLGRVVNP 441
PF F I +SG +LFLGR +P
Sbjct: 356 HPFLFFIRHNSSGSILFLGRFSSP 379
>gi|21361302 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 4 [Homo
sapiens]
Length = 427
Score = 164 bits (416), Expect = 1e-40
Identities = 113/381 (29%), Positives = 195/381 (51%), Gaps = 17/381 (4%)
Query: 74 QLAKETSNFGFSLLRKISMRHDG-NMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQA 132
++A ++F F I+ G N+ FSP +S A L LGA + +QI GL
Sbjct: 50 KIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNL 109
Query: 133 LKPTKPGLLPSLFKGLRETLS---RNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTE 189
+ ++ + F+ L TL+ LE + GS F+ + F N + ++ +
Sbjct: 110 TELSESDVHRG-FQHLLHTLNLPGHGLETRV--GSALFLSHNLKFLAKFLNDTMAVYEAK 166
Query: 190 CVPMNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPV 249
NF + +L+N ++ KETRGKI L E+ + ++LV+YI FK W PF
Sbjct: 167 LFHTNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISS 226
Query: 250 FTEVDTFHLDKYKTIKVPMMYGAGKFA-STFDKNFRCHVLKLPYQGNATMLVVLMEKMGD 308
T F++D+ T++VPMM + D+ C VL++ Y+G+AT+ +L G
Sbjct: 227 RTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFIL-PNQGK 285
Query: 309 HLALEDYLTTDLVETWLRNMKTRN----MEVFFPKFKLDQKYEMHELLRQMGIRRIFSPF 364
+E+ LT +++ W ++ RN +E+ PKF + Y + ++L ++G +FS +
Sbjct: 286 MREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKW 345
Query: 365 ADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPP---VIKVDRPFH 421
ADLS ++ + L+ S+ + ++VDE GTEA A I +S +++ +RPF
Sbjct: 346 ADLSGITKQ-QKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPFL 404
Query: 422 FMIYEETSGMLLFLGRVVNPT 442
+I+ ++ +LFLG+VV+PT
Sbjct: 405 VVIFSTSTQSVLFLGKVVDPT 425
>gi|170295807 neuroserpin precursor [Homo sapiens]
Length = 410
Score = 163 bits (412), Expect = 3e-40
Identities = 98/358 (27%), Positives = 188/358 (52%), Gaps = 14/358 (3%)
Query: 95 DGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQALKPTKPGLLPSLFKGLRETLSR 154
D N++FSP ++LAM + LGA G T+ +I+ + +LK + F + ++
Sbjct: 43 DENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDSLKNGEEFSFLKEFSNM--VTAK 100
Query: 155 NLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRNASQAKRLMNHYINKETR 214
+ + + F+ F V E F + K+YF+ ++F +N ++ T
Sbjct: 101 ESQYVMKIANSLFVQNGFHVNEEFLQMMKKYFNAAVNHVDFSQNVAVANYINKWVENNTN 160
Query: 215 GKIPKLFD--EINPETKLILVDYILFKGKWLTPFDPVFTEVDTFHLDKYKTIKVPMMYGA 272
+ L + + T L L++ + FKG W + F P T +F D +++PMMY
Sbjct: 161 NLVKDLVSPRDFDAATYLALINAVYFKGNWKSQFRPENTRTFSFTKDDESEVQIPMMYQQ 220
Query: 273 GKFA------STFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHLA-LEDYLTTDLVETWL 325
G+F + + VL++PY+G+ +++++ + LA LE + LVE W
Sbjct: 221 GEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVLSRQEVPLATLEPLVKAQLVEEWA 280
Query: 326 RNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSATGRNLQVSRVLQR 385
++K + +EV+ P+F ++Q+ ++ ++L+ +GI IF A+L+ LS + + +S+ + +
Sbjct: 281 NSVKKQKVEVYLPRFTVEQEIDLKDVLKALGITEIFIKDANLTGLS-DNKEIFLSKAIHK 339
Query: 386 TVIEVDERGTE--AVAGILSEITAYSMPPVIKVDRPFHFMIYEETSGMLLFLGRVVNP 441
+ +EV+E G+E AV+G+++ + P + VD PF F+I +G +LF+GRV++P
Sbjct: 340 SFLEVNEEGSEAAAVSGMIAISRMAVLYPQVIVDHPFFFLIRNRRTGTILFMGRVMHP 397
>gi|4826904 neuroserpin precursor [Homo sapiens]
Length = 410
Score = 163 bits (412), Expect = 3e-40
Identities = 98/358 (27%), Positives = 188/358 (52%), Gaps = 14/358 (3%)
Query: 95 DGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQALKPTKPGLLPSLFKGLRETLSR 154
D N++FSP ++LAM + LGA G T+ +I+ + +LK + F + ++
Sbjct: 43 DENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDSLKNGEEFSFLKEFSNM--VTAK 100
Query: 155 NLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRNASQAKRLMNHYINKETR 214
+ + + F+ F V E F + K+YF+ ++F +N ++ T
Sbjct: 101 ESQYVMKIANSLFVQNGFHVNEEFLQMMKKYFNAAVNHVDFSQNVAVANYINKWVENNTN 160
Query: 215 GKIPKLFD--EINPETKLILVDYILFKGKWLTPFDPVFTEVDTFHLDKYKTIKVPMMYGA 272
+ L + + T L L++ + FKG W + F P T +F D +++PMMY
Sbjct: 161 NLVKDLVSPRDFDAATYLALINAVYFKGNWKSQFRPENTRTFSFTKDDESEVQIPMMYQQ 220
Query: 273 GKFA------STFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHLA-LEDYLTTDLVETWL 325
G+F + + VL++PY+G+ +++++ + LA LE + LVE W
Sbjct: 221 GEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVLSRQEVPLATLEPLVKAQLVEEWA 280
Query: 326 RNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSATGRNLQVSRVLQR 385
++K + +EV+ P+F ++Q+ ++ ++L+ +GI IF A+L+ LS + + +S+ + +
Sbjct: 281 NSVKKQKVEVYLPRFTVEQEIDLKDVLKALGITEIFIKDANLTGLS-DNKEIFLSKAIHK 339
Query: 386 TVIEVDERGTE--AVAGILSEITAYSMPPVIKVDRPFHFMIYEETSGMLLFLGRVVNP 441
+ +EV+E G+E AV+G+++ + P + VD PF F+I +G +LF+GRV++P
Sbjct: 340 SFLEVNEEGSEAAAVSGMIAISRMAVLYPQVIVDHPFFFLIRNRRTGTILFMGRVMHP 397
>gi|122937297 serpin peptidase inhibitor, clade A (alpha-1
antiproteinase, antitrypsin), member 11 [Homo sapiens]
Length = 422
Score = 162 bits (410), Expect = 6e-40
Identities = 107/369 (28%), Positives = 192/369 (52%), Gaps = 11/369 (2%)
Query: 80 SNFGFSLLRKISMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQALKPTKPG 139
+NF L ++++ GN+ FSP +S + L LGA T I GL L T
Sbjct: 55 TNFALRLYKELAADAPGNIFFSPVSISTTLALLSLGAQANTSALILEGLGFN-LTETPEA 113
Query: 140 LLPSLFKGLRETLSR-NLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRNA 198
+ F+ L TL+ + +L L G+ F+ K ++ + + K + NF ++
Sbjct: 114 DIHQGFRSLLHTLALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGAFAFSANFTDS 173
Query: 199 SQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPVFTE-VDTFH 257
R +N Y+ ++T G++ E + +T ++L +YI FK KW PF T+ ++F
Sbjct: 174 VTTGRQINDYLRRQTYGQVVDCLPEFSQDTFMVLANYIFFKAKWKHPFSRYQTQKQESFF 233
Query: 258 LDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHLALEDYLT 317
+D+ +++VPMM+ +D++ C VL++ Y+GNA L+VL + G +E L
Sbjct: 234 VDERTSLQVPMMHQKEMHRFLYDQDLACTVLQIEYRGNALALLVLPDP-GKMKQVEAALQ 292
Query: 318 TDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSATGR-N 376
+ W + + +++ P+F + Y + ++L Q+G+ I + AD S TG+ N
Sbjct: 293 PQTLRKWGQLLLPSLLDLHLPRFSISGTYNLEDILPQIGLTNILNLEADFS--GVTGQLN 350
Query: 377 LQVSRVLQRTVIEVDERGTE--AVAGILSEITAYS--MPPVIKVDRPFHFMIYEETSGML 432
+S+V + ++++ E+GTE A +G+LS+ + + P +RPF +++E T+ L
Sbjct: 351 KTISKVSHKAMVDMSEKGTEAGAASGLLSQPPSLNTMSDPHAHFNRPFLLLLWEVTTQSL 410
Query: 433 LFLGRVVNP 441
LFLG+VVNP
Sbjct: 411 LFLGKVVNP 419
>gi|4758906 serpin peptidase inhibitor, clade B, member 9 [Homo
sapiens]
Length = 376
Score = 159 bits (403), Expect = 4e-39
Identities = 119/380 (31%), Positives = 189/380 (49%), Gaps = 16/380 (4%)
Query: 73 QQLAKETSNFGFSLLRKISMRHDGNMVF-SPFGMSLAMTGLMLGATGPTETQIKRGLHLQ 131
+ L+ + F LL+ + + + VF SP +S A+ ++LGA G T TQ+ + L L
Sbjct: 2 ETLSNASGTFAIRLLKILCQDNPSHNVFCSPVSISSALAMVLLGAKGNTATQMAQALSLN 61
Query: 132 ALKPTKPGLLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECV 191
T+ + + L E + L + F K TF +++ E
Sbjct: 62 ----TEEDIHRAFQSLLTEVNKAGTQYLLRTANRLFGEKTCQFLSTFKESCLQFYHAELK 117
Query: 192 PMNF-RNASQAKRLMNHYINKETRGKIPKLF--DEINPETKLILVDYILFKGKWLTPFDP 248
++F R A ++++ +N +++K+T GKI +L I+ ET+L+LV+ I FKGKW PFD
Sbjct: 118 ELSFIRAAEESRKHINTWVSKKTEGKIEELLPGSSIDAETRLVLVNAIYFKGKWNEPFDE 177
Query: 249 VFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGD 308
+T F +++ + V MMY F R +L+LPY L+VL+ G
Sbjct: 178 TYTREMPFKINQEEQRPVQMMYQEATFKLAHVGEVRAQLLELPYARKELSLLVLLPDDGV 237
Query: 309 HLA-LEDYLTTDLVETWLRN--MKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSP-F 364
L+ +E LT + + W + MK+ +EV PKFKL + Y+M +LR +GI F
Sbjct: 238 ELSTVEKSLTFEKLTAWTKPDCMKSTEVEVLLPKFKLQEDYDMESVLRHLGIVDAFQQGK 297
Query: 365 ADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITA---YSMPPVIKVDRPFH 421
ADLS +SA R+L +S+ + ++ +EV+E GTEA A + A P D PF
Sbjct: 298 ADLSAMSAE-RDLCLSKFVHKSFVEVNEEGTEAAAASSCFVVAECCMESGPRFCADHPFL 356
Query: 422 FMIYEETSGMLLFLGRVVNP 441
F I + +LF GR +P
Sbjct: 357 FFIRHNRANSILFCGRFSSP 376
>gi|4502261 serpin peptidase inhibitor, clade C, member 1 [Homo
sapiens]
Length = 464
Score = 158 bits (399), Expect = 1e-38
Identities = 127/451 (28%), Positives = 210/451 (46%), Gaps = 24/451 (5%)
Query: 8 LLSVLLAQVWLVPGLAPSPQSPETPAPQN--QTSRVVQAPKEEEEDEQEASEEKASE--E 63
LLS+LL W SP T P++ + E++ E E SE+K E
Sbjct: 18 LLSLLLIGFWDCVTCHGSPVDICTAKPRDIPMNPMCIYRSPEKKATEDEGSEQKIPEATN 77
Query: 64 EKAWLMASRQQLAKETSNFGFSLLRKI--SMRHDGNMVFSPFGMSLAMTGLMLGATGPTE 121
+ W +L+K S F + + + S + N+ SP +S A LGA T
Sbjct: 78 RRVW------ELSKANSRFATTFYQHLADSKNDNDNIFLSPLSISTAFAMTKLGACNDTL 131
Query: 122 TQIKRGLHLQALKPTKPGLLPSLFKGLRETLSR--NLELGLTQGSFAFIHKDFDVKETFF 179
Q+ + + F L L R N L + F K ET+
Sbjct: 132 QQLMEVFKFDTISEKTSDQIHFFFAKLNCRLYRKANKSSKLVSANRLFGDKSLTFNETYQ 191
Query: 180 NLSKRYFDTECVPMNFR-NASQAKRLMNHYINKETRGKIPKLF--DEINPETKLILVDYI 236
++S+ + + P++F+ NA Q++ +N +++ +T G+I + + IN T L+LV+ I
Sbjct: 192 DISELVYGAKLQPLDFKENAEQSRAAINKWVSNKTEGRITDVIPSEAINELTVLVLVNTI 251
Query: 237 LFKGKWLTPFDPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNA 296
FKG W + F P T + F+ ++ MMY GKF VL+LP++G+
Sbjct: 252 YFKGLWKSKFSPENTRKELFYKADGESCSASMMYQEGKFRYRRVAE-GTQVLELPFKGDD 310
Query: 297 TMLVVLMEKMGDHLA-LEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQM 355
+V+++ K LA +E LT ++++ WL ++ + V P+F+++ + + E L+ M
Sbjct: 311 ITMVLILPKPEKSLAKVEKELTPEVLQEWLDELEEMMLVVHMPRFRIEDGFSLKEQLQDM 370
Query: 356 GIRRIFSP-FADLSELSATGR-NLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPP- 412
G+ +FSP + L + A GR +L VS + +EV+E G+EA A I S+ P
Sbjct: 371 GLVDLFSPEKSKLPGIVAEGRDDLYVSDAFHKAFLEVNEEGSEAAASTAVVIAGRSLNPN 430
Query: 413 --VIKVDRPFHFMIYEETSGMLLFLGRVVNP 441
K +RPF I E ++F+GRV NP
Sbjct: 431 RVTFKANRPFLVFIREVPLNTIIFMGRVANP 461
>gi|156071456 serpin peptidase inhibitor, clade B, member 11 [Homo
sapiens]
Length = 392
Score = 154 bits (389), Expect = 2e-37
Identities = 111/390 (28%), Positives = 200/390 (51%), Gaps = 30/390 (7%)
Query: 79 TSNFGFSL--LRKISMRHDG-NMVFSPFGMSLAMTGLMLGATGPTETQIKRGLH----LQ 131
T+N F L ++++ + G N+ FS + A++ ++LGA G TE Q+++ LH +
Sbjct: 6 TANVEFCLDVFKELNSNNIGDNIFFSSLSLLYALSMVLLGARGETEEQLEKVLHFSHTVD 65
Query: 132 ALKP--------TKPGLLPSLFKGLRETLSR---NLELGLTQGSFAFIHKDFDVKETFFN 180
+LKP ++ G + S F +++ N L + + K + + +
Sbjct: 66 SLKPGFKDSPKCSQAGRIHSEFGVEFSQINQPDSNCTLSIANRLYGT--KTMAFHQQYLS 123
Query: 181 LSKRYFDTECVPMNFRNASQ-AKRLMNHYINKETRGKIPKLFDE--INPETKLILVDYIL 237
S++++ ++F +++ ++ +N ++ +T GK+ LF + I+P + ++LV+ I
Sbjct: 124 CSEKWYQARLQTVDFEQSTEETRKTINAWVENKTNGKVANLFGKSTIDPSSVMVLVNAIY 183
Query: 238 FKGKWLTPFDPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGN-A 296
FKG+W F T F L + K + V MMY G F F K + VL+LPY N
Sbjct: 184 FKGQWQNKFQVRETVKSPFQLSEGKNVTVEMMYQIGTFKLAFVKEPQMQVLELPYVNNKL 243
Query: 297 TMLVVLMEKMGDHLALEDYLTTDLVETWL--RNMKTRNMEVFFPKFKLDQKYEMHELLRQ 354
+M+++L + + +E L + W NM R +EV P+FKL+ KYE++ LL+
Sbjct: 244 SMIILLPVGIANLKQIEKQLNSGTFHEWTSSSNMMEREVEVHLPRFKLETKYELNSLLKS 303
Query: 355 MGIRRIFSPF-ADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMP-- 411
+G+ +F+ ADLS +S T + L +S+ + ++ ++V E GTEA A I S+P
Sbjct: 304 LGVTDLFNQVKADLSGMSPT-KGLYLSKAIHKSYLDVSEEGTEAAAATGDSIAVKSLPMR 362
Query: 412 PVIKVDRPFHFMIYEETSGMLLFLGRVVNP 441
K + PF F I + +LF G++ +P
Sbjct: 363 AQFKANHPFLFFIRHTHTNTILFCGKLASP 392
>gi|41152086 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 6 [Homo sapiens]
Length = 376
Score = 151 bits (382), Expect = 1e-36
Identities = 110/380 (28%), Positives = 186/380 (48%), Gaps = 20/380 (5%)
Query: 75 LAKETSNFGFSLLRKISMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQALK 134
LA+ F +LL+ + + N+ FSP MS A+ + +GA G T Q+ Q L
Sbjct: 4 LAEANGTFALNLLKTLGKDNSKNVFFSPMSMSCALAMVYMGAKGNTAAQMA-----QILS 58
Query: 135 PTKPGLLPSLFKGLRETLSRNLELG----LTQGSFAFIHKDFDVKETFFNLSKRYFDTEC 190
K G + +G + L+ + G L + F K D +F + ++++ E
Sbjct: 59 FNKSGGGGDIHQGFQSLLTEVNKTGTQYLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEM 118
Query: 191 VPMNFRNA-SQAKRLMNHYINKETRGKIPKLFD--EINPETKLILVDYILFKGKWLTPFD 247
++F +A ++++ +N ++ ++T GKI +L ++P T+L+LV+ + F+G W FD
Sbjct: 119 EELDFISAVEKSRKHINTWVAEKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFD 178
Query: 248 PVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQG-NATMLVVLMEKM 306
TE F + K + V MM+ F T+ +L LPY G M+++L ++
Sbjct: 179 KENTEERLFKVSKNEEKPVQMMFKQSTFKKTYIGEIFTQILVLPYVGKELNMIIMLPDET 238
Query: 307 GDHLALEDYLTTDLVETWLR--NMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFS-P 363
D +E LT + W R M +EV P+FKL++ Y+M +LR +G+ F
Sbjct: 239 TDLRTVEKELTYEKFVEWTRLDMMDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAFELG 298
Query: 364 FADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVA--GILSEITAYSMPPVIKVDRPFH 421
AD S +S T +L +S+V+ ++ +EV+E GTEA A + + P D PF
Sbjct: 299 KADFSGMSQT--DLSLSKVVHKSFVEVNEEGTEAAAATAAIMMMRCARFVPRFCADHPFL 356
Query: 422 FMIYEETSGMLLFLGRVVNP 441
F I + +LF GR +P
Sbjct: 357 FFIQHSKTNGILFCGRFSSP 376
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.395
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,251,439
Number of Sequences: 37866
Number of extensions: 745704
Number of successful extensions: 11254
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 183
Number of HSP's successfully gapped in prelim test: 73
Number of HSP's that attempted gapping in prelim test: 8955
Number of HSP's gapped (non-prelim): 1394
length of query: 444
length of database: 18,247,518
effective HSP length: 105
effective length of query: 339
effective length of database: 14,271,588
effective search space: 4838068332
effective search space used: 4838068332
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.