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Search of human proteins with 15431332
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|15431332 caspase 1 isoform delta [Homo sapiens]
(263 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|15431332 caspase 1 isoform delta [Homo sapiens] 535 e-152
gi|15431330 caspase 1 isoform gamma precursor [Homo sapiens] 512 e-145
gi|4502573 caspase 1 isoform beta precursor [Homo sapiens] 477 e-135
gi|15431328 caspase 1 isoform alpha precursor [Homo sapiens] 476 e-135
gi|15451910 caspase 4 isoform gamma precursor [Homo sapiens] 269 2e-72
gi|4502577 caspase 4 isoform alpha precursor [Homo sapiens] 269 2e-72
gi|209870079 caspase 5 isoform f precursor [Homo sapiens] 258 4e-69
gi|209870073 caspase 5 isoform c [Homo sapiens] 258 4e-69
gi|209870071 caspase 5 isoform b precursor [Homo sapiens] 258 4e-69
gi|209870069 caspase 5 isoform a precursor [Homo sapiens] 258 4e-69
gi|209870075 caspase 5 isoform d [Homo sapiens] 197 1e-50
gi|15431334 caspase 1 isoform epsilon [Homo sapiens] 155 4e-38
gi|39995059 caspase 2 isoform 1 preproprotein [Homo sapiens] 96 2e-20
gi|6912286 caspase 14 precursor [Homo sapiens] 74 1e-13
gi|47078272 caspase 10 isoform d preproprotein [Homo sapiens] 63 3e-10
gi|47078269 caspase 10 isoform b preproprotein [Homo sapiens] 63 3e-10
gi|47078267 caspase 10 isoform a preproprotein [Homo sapiens] 62 5e-10
gi|62953113 caspase-1 dominant-negative inhibitor pseudo-ICE iso... 61 9e-10
gi|14790115 caspase 3 preproprotein [Homo sapiens] 61 1e-09
gi|14790119 caspase 3 preproprotein [Homo sapiens] 61 1e-09
gi|14790124 caspase 9 isoform alpha preproprotein [Homo sapiens] 59 3e-09
gi|14916483 caspase 6 isoform alpha preproprotein [Homo sapiens] 55 5e-08
gi|122056476 caspase 8 isoform G precursor [Homo sapiens] 53 3e-07
gi|15718706 caspase 8 isoform B precursor [Homo sapiens] 53 3e-07
gi|15718698 caspase 7 isoform delta [Homo sapiens] 53 3e-07
gi|15718700 caspase 7 isoform alpha [Homo sapiens] 53 3e-07
gi|4502581 caspase 7 isoform alpha precursor [Homo sapiens] 53 3e-07
gi|122056474 caspase 8 isoform C precursor [Homo sapiens] 52 4e-07
gi|15718708 caspase 8 isoform C precursor [Homo sapiens] 52 4e-07
gi|15718704 caspase 8 isoform A precursor [Homo sapiens] 52 4e-07
>gi|15431332 caspase 1 isoform delta [Homo sapiens]
Length = 263
Score = 535 bits (1377), Expect = e-152
Identities = 263/263 (100%), Positives = 263/263 (100%)
Query: 1 MADKVLKEKRKLFIRSMGEAPQAVQDNPAMPTSSGSEGNVKLCSLEEAQRIWKQKSAEIY 60
MADKVLKEKRKLFIRSMGEAPQAVQDNPAMPTSSGSEGNVKLCSLEEAQRIWKQKSAEIY
Sbjct: 1 MADKVLKEKRKLFIRSMGEAPQAVQDNPAMPTSSGSEGNVKLCSLEEAQRIWKQKSAEIY 60
Query: 61 PIMDKSSRTRLALIICNEEFDSIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTT 120
PIMDKSSRTRLALIICNEEFDSIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTT
Sbjct: 61 PIMDKSSRTRLALIICNEEFDSIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTT 120
Query: 121 ELEAFAHRPEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSL 180
ELEAFAHRPEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSL
Sbjct: 121 ELEAFAHRPEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSL 180
Query: 181 KDKPKVIIIQACRGDNVSWRHPTMGSVFIGRLIEHMQEYACSCDVEEIFRKVRFSFEQPD 240
KDKPKVIIIQACRGDNVSWRHPTMGSVFIGRLIEHMQEYACSCDVEEIFRKVRFSFEQPD
Sbjct: 181 KDKPKVIIIQACRGDNVSWRHPTMGSVFIGRLIEHMQEYACSCDVEEIFRKVRFSFEQPD 240
Query: 241 GRAQMPTTERVTLTRCFYLFPGH 263
GRAQMPTTERVTLTRCFYLFPGH
Sbjct: 241 GRAQMPTTERVTLTRCFYLFPGH 263
>gi|15431330 caspase 1 isoform gamma precursor [Homo sapiens]
Length = 311
Score = 512 bits (1318), Expect = e-145
Identities = 263/311 (84%), Positives = 263/311 (84%), Gaps = 48/311 (15%)
Query: 1 MADKVLKEKRKLFIRSMGEAPQAVQDNPAMPTSSGSEGNVKLCSLEEAQRIWKQKSAEIY 60
MADKVLKEKRKLFIRSMGEAPQAVQDNPAMPTSSGSEGNVKLCSLEEAQRIWKQKSAEIY
Sbjct: 1 MADKVLKEKRKLFIRSMGEAPQAVQDNPAMPTSSGSEGNVKLCSLEEAQRIWKQKSAEIY 60
Query: 61 PIMDKSSRTRLALIICNEEFDSIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTT 120
PIMDKSSRTRLALIICNEEFDSIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTT
Sbjct: 61 PIMDKSSRTRLALIICNEEFDSIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTT 120
Query: 121 ELEAFAHRPEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSL 180
ELEAFAHRPEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSL
Sbjct: 121 ELEAFAHRPEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSL 180
Query: 181 KDKPKVIIIQACRG---------------------------------------------- 194
KDKPKVIIIQACRG
Sbjct: 181 KDKPKVIIIQACRGDSPGVVWFKDSVGVSGNLSLPTTEEFEDDAIKKAHIEKDFIAFCSS 240
Query: 195 --DNVSWRHPTMGSVFIGRLIEHMQEYACSCDVEEIFRKVRFSFEQPDGRAQMPTTERVT 252
DNVSWRHPTMGSVFIGRLIEHMQEYACSCDVEEIFRKVRFSFEQPDGRAQMPTTERVT
Sbjct: 241 TPDNVSWRHPTMGSVFIGRLIEHMQEYACSCDVEEIFRKVRFSFEQPDGRAQMPTTERVT 300
Query: 253 LTRCFYLFPGH 263
LTRCFYLFPGH
Sbjct: 301 LTRCFYLFPGH 311
>gi|4502573 caspase 1 isoform beta precursor [Homo sapiens]
Length = 383
Score = 477 bits (1227), Expect = e-135
Identities = 244/295 (82%), Positives = 245/295 (83%), Gaps = 48/295 (16%)
Query: 17 MGEAPQAVQDNPAMPTSSGSEGNVKLCSLEEAQRIWKQKSAEIYPIMDKSSRTRLALIIC 76
+ APQAVQDNPAMPTSSGSEGNVKLCSLEEAQRIWKQKSAEIYPIMDKSSRTRLALIIC
Sbjct: 89 LSAAPQAVQDNPAMPTSSGSEGNVKLCSLEEAQRIWKQKSAEIYPIMDKSSRTRLALIIC 148
Query: 77 NEEFDSIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHRPEHKTSDS 136
NEEFDSIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHRPEHKTSDS
Sbjct: 149 NEEFDSIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHRPEHKTSDS 208
Query: 137 TFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVIIIQACRG-- 194
TFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVIIIQACRG
Sbjct: 209 TFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVIIIQACRGDS 268
Query: 195 ----------------------------------------------DNVSWRHPTMGSVF 208
DNVSWRHPTMGSVF
Sbjct: 269 PGVVWFKDSVGVSGNLSLPTTEEFEDDAIKKAHIEKDFIAFCSSTPDNVSWRHPTMGSVF 328
Query: 209 IGRLIEHMQEYACSCDVEEIFRKVRFSFEQPDGRAQMPTTERVTLTRCFYLFPGH 263
IGRLIEHMQEYACSCDVEEIFRKVRFSFEQPDGRAQMPTTERVTLTRCFYLFPGH
Sbjct: 329 IGRLIEHMQEYACSCDVEEIFRKVRFSFEQPDGRAQMPTTERVTLTRCFYLFPGH 383
Score = 40.0 bits (92), Expect = 0.002
Identities = 19/19 (100%), Positives = 19/19 (100%)
Query: 1 MADKVLKEKRKLFIRSMGE 19
MADKVLKEKRKLFIRSMGE
Sbjct: 1 MADKVLKEKRKLFIRSMGE 19
>gi|15431328 caspase 1 isoform alpha precursor [Homo sapiens]
Length = 404
Score = 476 bits (1226), Expect = e-135
Identities = 244/292 (83%), Positives = 244/292 (83%), Gaps = 48/292 (16%)
Query: 20 APQAVQDNPAMPTSSGSEGNVKLCSLEEAQRIWKQKSAEIYPIMDKSSRTRLALIICNEE 79
APQAVQDNPAMPTSSGSEGNVKLCSLEEAQRIWKQKSAEIYPIMDKSSRTRLALIICNEE
Sbjct: 113 APQAVQDNPAMPTSSGSEGNVKLCSLEEAQRIWKQKSAEIYPIMDKSSRTRLALIICNEE 172
Query: 80 FDSIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHRPEHKTSDSTFL 139
FDSIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHRPEHKTSDSTFL
Sbjct: 173 FDSIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHRPEHKTSDSTFL 232
Query: 140 VFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVIIIQACRG----- 194
VFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVIIIQACRG
Sbjct: 233 VFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVIIIQACRGDSPGV 292
Query: 195 -------------------------------------------DNVSWRHPTMGSVFIGR 211
DNVSWRHPTMGSVFIGR
Sbjct: 293 VWFKDSVGVSGNLSLPTTEEFEDDAIKKAHIEKDFIAFCSSTPDNVSWRHPTMGSVFIGR 352
Query: 212 LIEHMQEYACSCDVEEIFRKVRFSFEQPDGRAQMPTTERVTLTRCFYLFPGH 263
LIEHMQEYACSCDVEEIFRKVRFSFEQPDGRAQMPTTERVTLTRCFYLFPGH
Sbjct: 353 LIEHMQEYACSCDVEEIFRKVRFSFEQPDGRAQMPTTERVTLTRCFYLFPGH 404
Score = 40.0 bits (92), Expect = 0.002
Identities = 19/19 (100%), Positives = 19/19 (100%)
Query: 1 MADKVLKEKRKLFIRSMGE 19
MADKVLKEKRKLFIRSMGE
Sbjct: 1 MADKVLKEKRKLFIRSMGE 19
>gi|15451910 caspase 4 isoform gamma precursor [Homo sapiens]
Length = 321
Score = 269 bits (687), Expect = 2e-72
Identities = 143/281 (50%), Positives = 177/281 (62%), Gaps = 48/281 (17%)
Query: 31 PTSSGSEGNVKLCSLEEAQRIWKQKSAEIYPIMDKSSRTRLALIICNEEFDSIPRRTGAE 90
P S S +KLC EE R+ K+++ EIYPI ++++RTRLALIICN EFD +P R GA+
Sbjct: 41 PESGESTDALKLCPHEEFLRLCKERAEEIYPIKERNNRTRLALIICNTEFDHLPPRNGAD 100
Query: 91 VDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHRPEHKTSDSTFLVFMSHGIREGI 150
DITGM LL+ L YSVDV++NLTA DM + L AFA RPEHK+SDSTFLV MSHGI EGI
Sbjct: 101 FDITGMKELLEGLDYSVDVEENLTARDMESALRAFATRPEHKSSDSTFLVLMSHGILEGI 160
Query: 151 CGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVIIIQACRG---------------- 194
CG H E+ PD+L + IF + N +NC SLKDKPKVII+QACRG
Sbjct: 161 CGTVHDEKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGANRGELWVRDSPASLE 220
Query: 195 --------------------------------DNVSWRHPTMGSVFIGRLIEHMQEYACS 222
NVSWR TMGS+FI +LI Q+Y+
Sbjct: 221 VASSQSSENLEEDAVYKTHVEKDFIAFCSSTPHNVSWRDSTMGSIFITQLITCFQKYSWC 280
Query: 223 CDVEEIFRKVRFSFEQPDGRAQMPTTERVTLTRCFYLFPGH 263
C +EE+FRKV+ SFE P +AQMPT ER+++TR FYLFPG+
Sbjct: 281 CHLEEVFRKVQQSFETPRAKAQMPTIERLSMTRYFYLFPGN 321
>gi|4502577 caspase 4 isoform alpha precursor [Homo sapiens]
Length = 377
Score = 269 bits (687), Expect = 2e-72
Identities = 143/281 (50%), Positives = 177/281 (62%), Gaps = 48/281 (17%)
Query: 31 PTSSGSEGNVKLCSLEEAQRIWKQKSAEIYPIMDKSSRTRLALIICNEEFDSIPRRTGAE 90
P S S +KLC EE R+ K+++ EIYPI ++++RTRLALIICN EFD +P R GA+
Sbjct: 97 PESGESTDALKLCPHEEFLRLCKERAEEIYPIKERNNRTRLALIICNTEFDHLPPRNGAD 156
Query: 91 VDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHRPEHKTSDSTFLVFMSHGIREGI 150
DITGM LL+ L YSVDV++NLTA DM + L AFA RPEHK+SDSTFLV MSHGI EGI
Sbjct: 157 FDITGMKELLEGLDYSVDVEENLTARDMESALRAFATRPEHKSSDSTFLVLMSHGILEGI 216
Query: 151 CGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVIIIQACRG---------------- 194
CG H E+ PD+L + IF + N +NC SLKDKPKVII+QACRG
Sbjct: 217 CGTVHDEKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGANRGELWVRDSPASLE 276
Query: 195 --------------------------------DNVSWRHPTMGSVFIGRLIEHMQEYACS 222
NVSWR TMGS+FI +LI Q+Y+
Sbjct: 277 VASSQSSENLEEDAVYKTHVEKDFIAFCSSTPHNVSWRDSTMGSIFITQLITCFQKYSWC 336
Query: 223 CDVEEIFRKVRFSFEQPDGRAQMPTTERVTLTRCFYLFPGH 263
C +EE+FRKV+ SFE P +AQMPT ER+++TR FYLFPG+
Sbjct: 337 CHLEEVFRKVQQSFETPRAKAQMPTIERLSMTRYFYLFPGN 377
>gi|209870079 caspase 5 isoform f precursor [Homo sapiens]
Length = 447
Score = 258 bits (659), Expect = 4e-69
Identities = 141/281 (50%), Positives = 167/281 (59%), Gaps = 48/281 (17%)
Query: 31 PTSSGSEGNVKLCSLEEAQRIWKQKSAEIYPIMDKSSRTRLALIICNEEFDSIPRRTGAE 90
P S+ S +KLC EE R+ K+ EIYPI + R RLALIICN +FD +P R GA
Sbjct: 167 PESAESTNILKLCPREEFLRLCKKNHDEIYPIKKREDRRRLALIICNTKFDHLPARNGAH 226
Query: 91 VDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHRPEHKTSDSTFLVFMSHGIREGI 150
DI GM LLQ LGY+V +KNLTA DM + L AFA RPEHK+SDSTFLV MSHGI EGI
Sbjct: 227 YDIVGMKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGI 286
Query: 151 CGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVIIIQACRGD--------------- 195
CG H ++ PD+L + IF + N +NC SLKDKPKVII+QACRG+
Sbjct: 287 CGTAHKKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLA 346
Query: 196 ---------------------------------NVSWRHPTMGSVFIGRLIEHMQEYACS 222
NVSWR T GS+FI LI Q+Y+C
Sbjct: 347 LISSQSSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCC 406
Query: 223 CDVEEIFRKVRFSFEQPDGRAQMPTTERVTLTRCFYLFPGH 263
C + EIFRKV+ SFE P +AQMPT ER TLTR FYLFPG+
Sbjct: 407 CHLMEIFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN 447
>gi|209870073 caspase 5 isoform c [Homo sapiens]
Length = 292
Score = 258 bits (659), Expect = 4e-69
Identities = 141/281 (50%), Positives = 167/281 (59%), Gaps = 48/281 (17%)
Query: 31 PTSSGSEGNVKLCSLEEAQRIWKQKSAEIYPIMDKSSRTRLALIICNEEFDSIPRRTGAE 90
P S+ S +KLC EE R+ K+ EIYPI + R RLALIICN +FD +P R GA
Sbjct: 12 PESAESTNILKLCPREEFLRLCKKNHDEIYPIKKREDRRRLALIICNTKFDHLPARNGAH 71
Query: 91 VDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHRPEHKTSDSTFLVFMSHGIREGI 150
DI GM LLQ LGY+V +KNLTA DM + L AFA RPEHK+SDSTFLV MSHGI EGI
Sbjct: 72 YDIVGMKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGI 131
Query: 151 CGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVIIIQACRGD--------------- 195
CG H ++ PD+L + IF + N +NC SLKDKPKVII+QACRG+
Sbjct: 132 CGTAHKKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLA 191
Query: 196 ---------------------------------NVSWRHPTMGSVFIGRLIEHMQEYACS 222
NVSWR T GS+FI LI Q+Y+C
Sbjct: 192 LISSQSSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCC 251
Query: 223 CDVEEIFRKVRFSFEQPDGRAQMPTTERVTLTRCFYLFPGH 263
C + EIFRKV+ SFE P +AQMPT ER TLTR FYLFPG+
Sbjct: 252 CHLMEIFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN 292
>gi|209870071 caspase 5 isoform b precursor [Homo sapiens]
Length = 376
Score = 258 bits (659), Expect = 4e-69
Identities = 141/281 (50%), Positives = 167/281 (59%), Gaps = 48/281 (17%)
Query: 31 PTSSGSEGNVKLCSLEEAQRIWKQKSAEIYPIMDKSSRTRLALIICNEEFDSIPRRTGAE 90
P S+ S +KLC EE R+ K+ EIYPI + R RLALIICN +FD +P R GA
Sbjct: 96 PESAESTNILKLCPREEFLRLCKKNHDEIYPIKKREDRRRLALIICNTKFDHLPARNGAH 155
Query: 91 VDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHRPEHKTSDSTFLVFMSHGIREGI 150
DI GM LLQ LGY+V +KNLTA DM + L AFA RPEHK+SDSTFLV MSHGI EGI
Sbjct: 156 YDIVGMKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGI 215
Query: 151 CGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVIIIQACRGD--------------- 195
CG H ++ PD+L + IF + N +NC SLKDKPKVII+QACRG+
Sbjct: 216 CGTAHKKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLA 275
Query: 196 ---------------------------------NVSWRHPTMGSVFIGRLIEHMQEYACS 222
NVSWR T GS+FI LI Q+Y+C
Sbjct: 276 LISSQSSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCC 335
Query: 223 CDVEEIFRKVRFSFEQPDGRAQMPTTERVTLTRCFYLFPGH 263
C + EIFRKV+ SFE P +AQMPT ER TLTR FYLFPG+
Sbjct: 336 CHLMEIFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN 376
>gi|209870069 caspase 5 isoform a precursor [Homo sapiens]
Length = 434
Score = 258 bits (659), Expect = 4e-69
Identities = 141/281 (50%), Positives = 167/281 (59%), Gaps = 48/281 (17%)
Query: 31 PTSSGSEGNVKLCSLEEAQRIWKQKSAEIYPIMDKSSRTRLALIICNEEFDSIPRRTGAE 90
P S+ S +KLC EE R+ K+ EIYPI + R RLALIICN +FD +P R GA
Sbjct: 154 PESAESTNILKLCPREEFLRLCKKNHDEIYPIKKREDRRRLALIICNTKFDHLPARNGAH 213
Query: 91 VDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHRPEHKTSDSTFLVFMSHGIREGI 150
DI GM LLQ LGY+V +KNLTA DM + L AFA RPEHK+SDSTFLV MSHGI EGI
Sbjct: 214 YDIVGMKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGI 273
Query: 151 CGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVIIIQACRGD--------------- 195
CG H ++ PD+L + IF + N +NC SLKDKPKVII+QACRG+
Sbjct: 274 CGTAHKKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLA 333
Query: 196 ---------------------------------NVSWRHPTMGSVFIGRLIEHMQEYACS 222
NVSWR T GS+FI LI Q+Y+C
Sbjct: 334 LISSQSSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCC 393
Query: 223 CDVEEIFRKVRFSFEQPDGRAQMPTTERVTLTRCFYLFPGH 263
C + EIFRKV+ SFE P +AQMPT ER TLTR FYLFPG+
Sbjct: 394 CHLMEIFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN 434
>gi|209870075 caspase 5 isoform d [Homo sapiens]
Length = 216
Score = 197 bits (500), Expect = 1e-50
Identities = 108/216 (50%), Positives = 127/216 (58%), Gaps = 48/216 (22%)
Query: 96 MTMLLQNLGYSVDVKKNLTASDMTTELEAFAHRPEHKTSDSTFLVFMSHGIREGICGKKH 155
M LLQ LGY+V +KNLTA DM + L AFA RPEHK+SDSTFLV MSHGI EGICG H
Sbjct: 1 MKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAH 60
Query: 156 SEQVPDILQLNAIFNMLNTKNCPSLKDKPKVIIIQACRGD-------------------- 195
++ PD+L + IF + N +NC SLKDKPKVII+QACRG+
Sbjct: 61 KKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQ 120
Query: 196 ----------------------------NVSWRHPTMGSVFIGRLIEHMQEYACSCDVEE 227
NVSWR T GS+FI LI Q+Y+C C + E
Sbjct: 121 SSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLME 180
Query: 228 IFRKVRFSFEQPDGRAQMPTTERVTLTRCFYLFPGH 263
IFRKV+ SFE P +AQMPT ER TLTR FYLFPG+
Sbjct: 181 IFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN 216
>gi|15431334 caspase 1 isoform epsilon [Homo sapiens]
Length = 88
Score = 155 bits (391), Expect = 4e-38
Identities = 74/84 (88%), Positives = 78/84 (92%), Gaps = 1/84 (1%)
Query: 180 LKDKPKVIIIQACRGDNVSWRHPTMGSVFIGRLIEHMQEYACSCDVEEIFRKVRFSFEQP 239
LK+K K + I++ DNVSWRHPTMGSVFIGRLIEHMQEYACSCDVEEIFRKVRFSFEQP
Sbjct: 6 LKEKRK-LFIRSMGEDNVSWRHPTMGSVFIGRLIEHMQEYACSCDVEEIFRKVRFSFEQP 64
Query: 240 DGRAQMPTTERVTLTRCFYLFPGH 263
DGRAQMPTTERVTLTRCFYLFPGH
Sbjct: 65 DGRAQMPTTERVTLTRCFYLFPGH 88
Score = 40.0 bits (92), Expect = 0.002
Identities = 19/19 (100%), Positives = 19/19 (100%)
Query: 1 MADKVLKEKRKLFIRSMGE 19
MADKVLKEKRKLFIRSMGE
Sbjct: 1 MADKVLKEKRKLFIRSMGE 19
>gi|39995059 caspase 2 isoform 1 preproprotein [Homo sapiens]
Length = 452
Score = 96.3 bits (238), Expect = 2e-20
Identities = 75/259 (28%), Positives = 107/259 (41%), Gaps = 67/259 (25%)
Query: 67 SRTR-LALIICNEEFDS---IPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTEL 122
SR R LAL++ N F + R+G +VD + + L + LGY V V + TA +M +L
Sbjct: 196 SRPRGLALVLSNVHFTGEKELEFRSGGDVDHSTLVTLFKLLGYDVHVLCDQTAQEMQEKL 255
Query: 123 EAFAHRPEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKD 182
+ FA P H+ +DS + +SHG+ I G +LQL +F + + NCPSL++
Sbjct: 256 QNFAQLPAHRVTDSCIVALLSHGVEGAIYGVDGK-----LLQLQEVFQLFDNANCPSLQN 310
Query: 183 KPKVIIIQACRGD----------------------------------------------- 195
KPK+ IQACRGD
Sbjct: 311 KPKMFFIQACRGDETDRGVDQQDGKNHAGSPGCEESDAGKEKLPKMRLPTRSDMICGYAC 370
Query: 196 ---NVSWRHPTMGSVFIGRLIEHMQEYACSCDVEEIFRKVRFSFEQPDGRAQMPTTERV- 251
+ R+ GS +I L + E AC V ++ KV + +G A R
Sbjct: 371 LKGTAAMRNTKRGSWYIEALAQVFSERACDMHVADMLVKVNALIKDREGYAPGTEFHRCK 430
Query: 252 -------TLTRCFYLFPGH 263
TL R YLFPGH
Sbjct: 431 EMSEYCSTLCRHLYLFPGH 449
>gi|6912286 caspase 14 precursor [Homo sapiens]
Length = 242
Score = 74.3 bits (181), Expect = 1e-13
Identities = 48/131 (36%), Positives = 69/131 (52%), Gaps = 12/131 (9%)
Query: 67 SRTRLALIICNEEFDSIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFA 126
S RLALI+C + R G+E D+ + + + L + +K++ TA ELE F
Sbjct: 15 SGARLALILCVTK-----AREGSEEDLDALEHMFRQLRFESTMKRDPTAEQFQEELEKFQ 69
Query: 127 HRPEHKTS--DSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKP 184
+ + F+V M+HG REG + E V +L +F LN KNC +L+ KP
Sbjct: 70 QAIDSREDPVSCAFVVLMAHG-REGFLKGEDGEMV----KLENLFEALNNKNCQALRAKP 124
Query: 185 KVIIIQACRGD 195
KV IIQACRG+
Sbjct: 125 KVYIIQACRGE 135
>gi|47078272 caspase 10 isoform d preproprotein [Homo sapiens]
Length = 522
Score = 62.8 bits (151), Expect = 3e-10
Identities = 41/143 (28%), Positives = 67/143 (46%), Gaps = 7/143 (4%)
Query: 55 KSAEIYPIMDKSSRTRLALIICNEEFDSIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLT 114
K A +Y M+++ R L +I+ N F S+ R G D ++ + Q LG++V + N+T
Sbjct: 271 KRAAVYR-MNRNHRG-LCVIVNNHSFTSLKDRQGTHKDAEILSHVFQWLGFTVHIHNNVT 328
Query: 115 ASDMTTELEAFAHRPEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNT 174
+M L+ P H D ++HG R G +P + I +
Sbjct: 329 KVEMEMVLQKQKCNPAHADGDCFVFCILTHG-RFGAVYSSDEALIP----IREIMSHFTA 383
Query: 175 KNCPSLKDKPKVIIIQACRGDNV 197
CP L +KPK+ IQAC+G+ +
Sbjct: 384 LQCPRLAEKPKLFFIQACQGEEI 406
>gi|47078269 caspase 10 isoform b preproprotein [Homo sapiens]
Length = 521
Score = 62.8 bits (151), Expect = 3e-10
Identities = 41/143 (28%), Positives = 67/143 (46%), Gaps = 7/143 (4%)
Query: 55 KSAEIYPIMDKSSRTRLALIICNEEFDSIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLT 114
K A +Y M+++ R L +I+ N F S+ R G D ++ + Q LG++V + N+T
Sbjct: 271 KRAAVYR-MNRNHRG-LCVIVNNHSFTSLKDRQGTHKDAEILSHVFQWLGFTVHIHNNVT 328
Query: 115 ASDMTTELEAFAHRPEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNT 174
+M L+ P H D ++HG R G +P + I +
Sbjct: 329 KVEMEMVLQKQKCNPAHADGDCFVFCILTHG-RFGAVYSSDEALIP----IREIMSHFTA 383
Query: 175 KNCPSLKDKPKVIIIQACRGDNV 197
CP L +KPK+ IQAC+G+ +
Sbjct: 384 LQCPRLAEKPKLFFIQACQGEEI 406
>gi|47078267 caspase 10 isoform a preproprotein [Homo sapiens]
Length = 479
Score = 62.0 bits (149), Expect = 5e-10
Identities = 36/127 (28%), Positives = 58/127 (45%), Gaps = 5/127 (3%)
Query: 71 LALIICNEEFDSIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHRPE 130
L +I+ N F S+ R G D ++ + Q LG++V + N+T +M L+ P
Sbjct: 242 LCVIVNNHSFTSLKDRQGTHKDAEILSHVFQWLGFTVHIHNNVTKVEMEMVLQKQKCNPA 301
Query: 131 HKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVIIIQ 190
H D ++HG R G +P + I + CP L +KPK+ IQ
Sbjct: 302 HADGDCFVFCILTHG-RFGAVYSSDEALIP----IREIMSHFTALQCPRLAEKPKLFFIQ 356
Query: 191 ACRGDNV 197
AC+G+ +
Sbjct: 357 ACQGEEI 363
>gi|62953113 caspase-1 dominant-negative inhibitor pseudo-ICE
isoform 1 [Homo sapiens]
Length = 197
Score = 61.2 bits (147), Expect = 9e-10
Identities = 28/39 (71%), Positives = 31/39 (79%)
Query: 17 MGEAPQAVQDNPAMPTSSGSEGNVKLCSLEEAQRIWKQK 55
+ A QAVQDNPAMPT S EG +KLC LE+AQRIWKQK
Sbjct: 89 LSAALQAVQDNPAMPTCSSPEGRIKLCFLEDAQRIWKQK 127
Score = 38.1 bits (87), Expect = 0.008
Identities = 18/19 (94%), Positives = 18/19 (94%)
Query: 1 MADKVLKEKRKLFIRSMGE 19
MADKVLKEKRKLFI SMGE
Sbjct: 1 MADKVLKEKRKLFIHSMGE 19
>gi|14790115 caspase 3 preproprotein [Homo sapiens]
Length = 277
Score = 60.8 bits (146), Expect = 1e-09
Identities = 59/210 (28%), Positives = 81/210 (38%), Gaps = 50/210 (23%)
Query: 71 LALIICNEEFDS---IPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAH 127
L +II N+ F + R+G +VD + +NL Y V K +LT ++ EL
Sbjct: 46 LCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIV-ELMRDVS 104
Query: 128 RPEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVI 187
+ +H S V +SHG EGI + + L I N C SL KPK+
Sbjct: 105 KEDHSKRSSFVCVLLSHG-EEGIIFGTNGP-----VDLKKITNFFRGDRCRSLTGKPKLF 158
Query: 188 IIQACRGDNV------------------------------------SWRHPTMGSVFIGR 211
IIQACRG + SWR+ GS FI
Sbjct: 159 IIQACRGTELDCGIETDSGVDDDMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQS 218
Query: 212 LIEHMQEYACSCDVEEIF----RKVRFSFE 237
L +++YA + I RKV FE
Sbjct: 219 LCAMLKQYADKLEFMHILTRVNRKVATEFE 248
>gi|14790119 caspase 3 preproprotein [Homo sapiens]
Length = 277
Score = 60.8 bits (146), Expect = 1e-09
Identities = 59/210 (28%), Positives = 81/210 (38%), Gaps = 50/210 (23%)
Query: 71 LALIICNEEFDS---IPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAH 127
L +II N+ F + R+G +VD + +NL Y V K +LT ++ EL
Sbjct: 46 LCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIV-ELMRDVS 104
Query: 128 RPEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVI 187
+ +H S V +SHG EGI + + L I N C SL KPK+
Sbjct: 105 KEDHSKRSSFVCVLLSHG-EEGIIFGTNGP-----VDLKKITNFFRGDRCRSLTGKPKLF 158
Query: 188 IIQACRGDNV------------------------------------SWRHPTMGSVFIGR 211
IIQACRG + SWR+ GS FI
Sbjct: 159 IIQACRGTELDCGIETDSGVDDDMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQS 218
Query: 212 LIEHMQEYACSCDVEEIF----RKVRFSFE 237
L +++YA + I RKV FE
Sbjct: 219 LCAMLKQYADKLEFMHILTRVNRKVATEFE 248
>gi|14790124 caspase 9 isoform alpha preproprotein [Homo sapiens]
Length = 416
Score = 59.3 bits (142), Expect = 3e-09
Identities = 53/205 (25%), Positives = 88/205 (42%), Gaps = 22/205 (10%)
Query: 1 MADKVLKEKRKLFIRSMGEAPQAVQDNPAMPTSSGSEGNVKLCSLEEAQRIWKQKSAEIY 60
++ L+ + +R P+ ++ P GS G + +LE + +A++
Sbjct: 98 LSKPTLENLTPVVLRPEIRKPEVLRPETPRPVDIGSGGFGDVGALESLRG-----NADLA 152
Query: 61 PIMDKSSRTRLALIICNEEF---DSIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASD 117
I+ LII N F + RTG+ +D + +L + V+VK +LTA
Sbjct: 153 YILSMEPCGH-CLIINNVNFCRESGLRTRTGSNIDCEKLRRRFSSLHFMVEVKGDLTAKK 211
Query: 118 MTTELEAFAHRPEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDI-------LQLNAIFN 170
M L A + +H D +V +SHG C H + + + + I N
Sbjct: 212 MVLALLELAQQ-DHGALDCCVVVILSHG-----CQASHLQFPGAVYGTDGCPVSVEKIVN 265
Query: 171 MLNTKNCPSLKDKPKVIIIQACRGD 195
+ N +CPSL KPK+ IQAC G+
Sbjct: 266 IFNGTSCPSLGGKPKLFFIQACGGE 290
Score = 28.5 bits (62), Expect = 6.2
Identities = 15/50 (30%), Positives = 26/50 (52%)
Query: 197 VSWRHPTMGSVFIGRLIEHMQEYACSCDVEEIFRKVRFSFEQPDGRAQMP 246
VSWR P GS ++ L + +++A S D++ + +V + QMP
Sbjct: 352 VSWRDPKSGSWYVETLDDIFEQWAHSEDLQSLLLRVANAVSVKGIYKQMP 401
>gi|14916483 caspase 6 isoform alpha preproprotein [Homo sapiens]
Length = 293
Score = 55.5 bits (132), Expect = 5e-08
Identities = 39/131 (29%), Positives = 61/131 (46%), Gaps = 10/131 (7%)
Query: 68 RTRLALIICNEEFD---SIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEA 124
R +ALI +E F ++P R G D +T +LG+ V +L A ++ ++
Sbjct: 43 RRGIALIFNHERFFWHLTLPERRGTCADRDNLTRRFSDLGFEVKCFNDLKAEELLLKIHE 102
Query: 125 FAHRPEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKP 184
+ H +D VF+SHG EG H +++ + + C SL KP
Sbjct: 103 VS-TVSHADADCFVCVFLSHG--EG----NHIYAYDAKIEIQTLTGLFKGDKCHSLVGKP 155
Query: 185 KVIIIQACRGD 195
K+ IIQACRG+
Sbjct: 156 KIFIIQACRGN 166
>gi|122056476 caspase 8 isoform G precursor [Homo sapiens]
Length = 538
Score = 52.8 bits (125), Expect = 3e-07
Identities = 47/174 (27%), Positives = 73/174 (41%), Gaps = 17/174 (9%)
Query: 34 SGSEGNVKLCSLEEAQRIWKQKSAEIYPIMDKSSRTR-LALIICNEEF----------DS 82
S E + ++ ++ R +S + + S+ R LII N F S
Sbjct: 256 SNGEELCGVMTISDSPREQDSESQTLDKVYQMKSKPRGYCLIINNHNFAKAREKVPKLHS 315
Query: 83 IPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHRPEHKTSDSTFLVFM 142
I R G +D +T + L + + + T + L+ + +H D +
Sbjct: 316 IRDRNGTHLDAGALTTTFEELHFEIKPHDDCTVEQIYEILKIY-QLMDHSNMDCFICCIL 374
Query: 143 SHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVIIIQACRGDN 196
SHG + GI ++ P I +L + F L CPSL KPKV IQAC+GDN
Sbjct: 375 SHGDK-GIIYGTDGQEAP-IYELTSQFTGLK---CPSLAGKPKVFFIQACQGDN 423
>gi|15718706 caspase 8 isoform B precursor [Homo sapiens]
Length = 479
Score = 52.8 bits (125), Expect = 3e-07
Identities = 47/174 (27%), Positives = 73/174 (41%), Gaps = 17/174 (9%)
Query: 34 SGSEGNVKLCSLEEAQRIWKQKSAEIYPIMDKSSRTR-LALIICNEEF----------DS 82
S E + ++ ++ R +S + + S+ R LII N F S
Sbjct: 197 SNGEELCGVMTISDSPREQDSESQTLDKVYQMKSKPRGYCLIINNHNFAKAREKVPKLHS 256
Query: 83 IPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHRPEHKTSDSTFLVFM 142
I R G +D +T + L + + + T + L+ + +H D +
Sbjct: 257 IRDRNGTHLDAGALTTTFEELHFEIKPHDDCTVEQIYEILKIY-QLMDHSNMDCFICCIL 315
Query: 143 SHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVIIIQACRGDN 196
SHG + GI ++ P I +L + F L CPSL KPKV IQAC+GDN
Sbjct: 316 SHGDK-GIIYGTDGQEAP-IYELTSQFTGLK---CPSLAGKPKVFFIQACQGDN 364
>gi|15718698 caspase 7 isoform delta [Homo sapiens]
Length = 336
Score = 52.8 bits (125), Expect = 3e-07
Identities = 49/202 (24%), Positives = 78/202 (38%), Gaps = 49/202 (24%)
Query: 73 LIICNEEFDSIPR---RTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHRP 129
+II N+ FD + R G + D + ++LG+ V V + + + M L+ A
Sbjct: 104 IIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAKMQDLLKK-ASEE 162
Query: 130 EHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVIII 189
+H + + +SHG I GK + V I L A F C +L +KPK+ I
Sbjct: 163 DHTNAACFACILLSHGEENVIYGK---DGVTPIKDLTAHFR---GDRCKTLLEKPKLFFI 216
Query: 190 QACRGDNV---------------------------------------SWRHPTMGSVFIG 210
QACRG + SWR P GS F+
Sbjct: 217 QACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQ 276
Query: 211 RLIEHMQEYACSCDVEEIFRKV 232
L ++E+ ++ +I +V
Sbjct: 277 ALCSILEEHGKDLEIMQILTRV 298
>gi|15718700 caspase 7 isoform alpha [Homo sapiens]
Length = 303
Score = 52.8 bits (125), Expect = 3e-07
Identities = 49/202 (24%), Positives = 78/202 (38%), Gaps = 49/202 (24%)
Query: 73 LIICNEEFDSIPR---RTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHRP 129
+II N+ FD + R G + D + ++LG+ V V + + + M L+ A
Sbjct: 71 IIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAKMQDLLKK-ASEE 129
Query: 130 EHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVIII 189
+H + + +SHG I GK + V I L A F C +L +KPK+ I
Sbjct: 130 DHTNAACFACILLSHGEENVIYGK---DGVTPIKDLTAHFR---GDRCKTLLEKPKLFFI 183
Query: 190 QACRGDNV---------------------------------------SWRHPTMGSVFIG 210
QACRG + SWR P GS F+
Sbjct: 184 QACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQ 243
Query: 211 RLIEHMQEYACSCDVEEIFRKV 232
L ++E+ ++ +I +V
Sbjct: 244 ALCSILEEHGKDLEIMQILTRV 265
>gi|4502581 caspase 7 isoform alpha precursor [Homo sapiens]
Length = 303
Score = 52.8 bits (125), Expect = 3e-07
Identities = 49/202 (24%), Positives = 78/202 (38%), Gaps = 49/202 (24%)
Query: 73 LIICNEEFDSIPR---RTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHRP 129
+II N+ FD + R G + D + ++LG+ V V + + + M L+ A
Sbjct: 71 IIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAKMQDLLKK-ASEE 129
Query: 130 EHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVIII 189
+H + + +SHG I GK + V I L A F C +L +KPK+ I
Sbjct: 130 DHTNAACFACILLSHGEENVIYGK---DGVTPIKDLTAHFR---GDRCKTLLEKPKLFFI 183
Query: 190 QACRGDNV---------------------------------------SWRHPTMGSVFIG 210
QACRG + SWR P GS F+
Sbjct: 184 QACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQ 243
Query: 211 RLIEHMQEYACSCDVEEIFRKV 232
L ++E+ ++ +I +V
Sbjct: 244 ALCSILEEHGKDLEIMQILTRV 265
>gi|122056474 caspase 8 isoform C precursor [Homo sapiens]
Length = 464
Score = 52.4 bits (124), Expect = 4e-07
Identities = 43/142 (30%), Positives = 60/142 (42%), Gaps = 16/142 (11%)
Query: 65 KSSRTRLALIICNEEF----------DSIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLT 114
KS LII N F SI R G +D +T + L + + + T
Sbjct: 214 KSKPRGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFEIKPHDDCT 273
Query: 115 ASDMTTELEAFAHRPEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNT 174
+ L+ + +H D +SHG + GI ++ P I +L + F L
Sbjct: 274 VEQIYEILKIY-QLMDHSNMDCFICCILSHGDK-GIIYGTDGQEAP-IYELTSQFTGLK- 329
Query: 175 KNCPSLKDKPKVIIIQACRGDN 196
CPSL KPKV IQAC+GDN
Sbjct: 330 --CPSLAGKPKVFFIQACQGDN 349
>gi|15718708 caspase 8 isoform C precursor [Homo sapiens]
Length = 464
Score = 52.4 bits (124), Expect = 4e-07
Identities = 43/142 (30%), Positives = 60/142 (42%), Gaps = 16/142 (11%)
Query: 65 KSSRTRLALIICNEEF----------DSIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLT 114
KS LII N F SI R G +D +T + L + + + T
Sbjct: 214 KSKPRGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFEIKPHDDCT 273
Query: 115 ASDMTTELEAFAHRPEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNT 174
+ L+ + +H D +SHG + GI ++ P I +L + F L
Sbjct: 274 VEQIYEILKIY-QLMDHSNMDCFICCILSHGDK-GIIYGTDGQEAP-IYELTSQFTGLK- 329
Query: 175 KNCPSLKDKPKVIIIQACRGDN 196
CPSL KPKV IQAC+GDN
Sbjct: 330 --CPSLAGKPKVFFIQACQGDN 349
>gi|15718704 caspase 8 isoform A precursor [Homo sapiens]
Length = 496
Score = 52.4 bits (124), Expect = 4e-07
Identities = 43/142 (30%), Positives = 60/142 (42%), Gaps = 16/142 (11%)
Query: 65 KSSRTRLALIICNEEF----------DSIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLT 114
KS LII N F SI R G +D +T + L + + + T
Sbjct: 246 KSKPRGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFEIKPHDDCT 305
Query: 115 ASDMTTELEAFAHRPEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNT 174
+ L+ + +H D +SHG + GI ++ P I +L + F L
Sbjct: 306 VEQIYEILKIY-QLMDHSNMDCFICCILSHGDK-GIIYGTDGQEAP-IYELTSQFTGLK- 361
Query: 175 KNCPSLKDKPKVIIIQACRGDN 196
CPSL KPKV IQAC+GDN
Sbjct: 362 --CPSLAGKPKVFFIQACQGDN 381
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.134 0.397
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,764,555
Number of Sequences: 37866
Number of extensions: 387797
Number of successful extensions: 939
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 39
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 862
Number of HSP's gapped (non-prelim): 70
length of query: 263
length of database: 18,247,518
effective HSP length: 100
effective length of query: 163
effective length of database: 14,460,918
effective search space: 2357129634
effective search space used: 2357129634
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.