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Search of human proteins with 154091310
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|154091310 transient receptor potential cation channel,
subfamily M, member 3 isoform g [Homo sapiens]
(1569 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|154091310 transient receptor potential cation channel, subfam... 3156 0.0
gi|154091308 transient receptor potential cation channel, subfam... 3148 0.0
gi|154091318 transient receptor potential cation channel, subfam... 3088 0.0
gi|154091320 transient receptor potential cation channel, subfam... 3080 0.0
gi|154091314 transient receptor potential cation channel, subfam... 3080 0.0
gi|154091316 transient receptor potential cation channel, subfam... 3079 0.0
gi|154091312 transient receptor potential cation channel, subfam... 3071 0.0
gi|148612863 transient receptor potential cation channel, subfam... 1354 0.0
gi|18921093 transient receptor potential cation channel, subfami... 1252 0.0
gi|94538366 transient receptor potential cation channel, subfami... 1207 0.0
gi|4507689 transient receptor potential cation channel, subfamil... 521 e-147
gi|55953096 transient receptor potential cation channel, subfami... 518 e-146
gi|21314671 transient receptor potential cation channel, subfami... 467 e-131
gi|11225266 transient receptor potential cation channel, subfami... 460 e-129
gi|45935368 transient receptor potential cation channel, subfami... 450 e-126
gi|109689695 transient receptor potential cation channel, subfam... 276 1e-73
gi|209863032 transient receptor potential cation channel, subfam... 80 1e-14
gi|209863030 transient receptor potential cation channel, subfam... 80 1e-14
gi|209863026 transient receptor potential cation channel, subfam... 80 1e-14
gi|7706747 transient receptor potential cation channel, subfamil... 80 1e-14
gi|209863024 transient receptor potential cation channel, subfam... 78 6e-14
gi|6912736 transient receptor potential cation channel, subfamil... 71 7e-12
gi|209863028 transient receptor potential cation channel, subfam... 62 3e-09
gi|9966865 transient receptor potential cation channel, subfamil... 57 1e-07
gi|194733735 transient receptor potential cation channel, subfam... 57 2e-07
gi|4507687 transient receptor potential cation channel, subfamil... 57 2e-07
gi|5730102 transient receptor potential cation channel, subfamil... 54 9e-07
gi|21314682 transient receptor potential cation channel, subfami... 53 3e-06
gi|17505200 transient receptor potential cation channel, subfami... 50 1e-05
gi|4507685 transient receptor potential cation channel, subfamil... 47 2e-04
>gi|154091310 transient receptor potential cation channel, subfamily
M, member 3 isoform g [Homo sapiens]
Length = 1569
Score = 3156 bits (8183), Expect = 0.0
Identities = 1569/1569 (100%), Positives = 1569/1569 (100%)
Query: 1 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 60
MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT
Sbjct: 1 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 60
Query: 61 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 120
TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ
Sbjct: 61 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 120
Query: 121 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRCLPFFSLD 180
TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRCLPFFSLD
Sbjct: 121 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRCLPFFSLD 180
Query: 181 SRLFYSFWGSCQLDSVGIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRA 240
SRLFYSFWGSCQLDSVGIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRA
Sbjct: 181 SRLFYSFWGSCQLDSVGIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRA 240
Query: 241 SDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVF 300
SDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVF
Sbjct: 241 SDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVF 300
Query: 301 RMGSEGHQDIDLAILTALLKGANASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQ 360
RMGSEGHQDIDLAILTALLKGANASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQ
Sbjct: 301 RMGSEGHQDIDLAILTALLKGANASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQ 360
Query: 361 AMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLP 420
AMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLP
Sbjct: 361 AMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLP 420
Query: 421 PDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRDDIPLRRGRKTTKKREE 480
PDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRDDIPLRRGRKTTKKREE
Sbjct: 421 PDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRDDIPLRRGRKTTKKREE 480
Query: 481 EVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAH 540
EVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAH
Sbjct: 481 EVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAH 540
Query: 541 EASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQL 600
EASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQL
Sbjct: 541 EASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQL 600
Query: 601 AVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPY 660
AVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPY
Sbjct: 601 AVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPY 660
Query: 661 MSQAQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPL 720
MSQAQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPL
Sbjct: 661 MSQAQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPL 720
Query: 721 GRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVISYIFTLGIEKM 780
GRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVISYIFTLGIEKM
Sbjct: 721 GRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVISYIFTLGIEKM 780
Query: 781 REILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSDGRVIYCVNII 840
REILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSDGRVIYCVNII
Sbjct: 781 REILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSDGRVIYCVNII 840
Query: 841 YWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSW 900
YWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSW
Sbjct: 841 YWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSW 900
Query: 901 KLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLL 960
KLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLL
Sbjct: 901 KLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLL 960
Query: 961 VANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIF 1020
VANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIF
Sbjct: 961 VANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIF 1020
Query: 1021 QHLCCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERI 1080
QHLCCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERI
Sbjct: 1021 QHLCCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERI 1080
Query: 1081 RVTSERVENMSMRLEEVNEREHSMKASLQTVDIRLAQLEDLIGRMATALERLTGLERAES 1140
RVTSERVENMSMRLEEVNEREHSMKASLQTVDIRLAQLEDLIGRMATALERLTGLERAES
Sbjct: 1081 RVTSERVENMSMRLEEVNEREHSMKASLQTVDIRLAQLEDLIGRMATALERLTGLERAES 1140
Query: 1141 NKIRSRTSSDCTDAAYIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSPTLMPRMRSHS 1200
NKIRSRTSSDCTDAAYIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSPTLMPRMRSHS
Sbjct: 1141 NKIRSRTSSDCTDAAYIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSPTLMPRMRSHS 1200
Query: 1201 FYSVNMKDKGGIEKLESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLAIVPDSRRPSS 1260
FYSVNMKDKGGIEKLESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLAIVPDSRRPSS
Sbjct: 1201 FYSVNMKDKGGIEKLESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLAIVPDSRRPSS 1260
Query: 1261 CIDIYVSAMDELHCDIDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATLAPTDRPPSRS 1320
CIDIYVSAMDELHCDIDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATLAPTDRPPSRS
Sbjct: 1261 CIDIYVSAMDELHCDIDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATLAPTDRPPSRS 1320
Query: 1321 IDFEDITSMDTRSFSSDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATTPFLLEEAPIV 1380
IDFEDITSMDTRSFSSDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATTPFLLEEAPIV
Sbjct: 1321 IDFEDITSMDTRSFSSDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATTPFLLEEAPIV 1380
Query: 1381 KSHSFMFSPSRSYYANFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAFPGGLGDKVED 1440
KSHSFMFSPSRSYYANFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAFPGGLGDKVED
Sbjct: 1381 KSHSFMFSPSRSYYANFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAFPGGLGDKVED 1440
Query: 1441 LTCCHPEREAELSHPSSDSEENEAKGRRATIAISSQEGDNSERTLSNNITVPKIERANSY 1500
LTCCHPEREAELSHPSSDSEENEAKGRRATIAISSQEGDNSERTLSNNITVPKIERANSY
Sbjct: 1441 LTCCHPEREAELSHPSSDSEENEAKGRRATIAISSQEGDNSERTLSNNITVPKIERANSY 1500
Query: 1501 SAEEPSAPYAHTRKSFSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSLSMRRLSRTSA 1560
SAEEPSAPYAHTRKSFSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSLSMRRLSRTSA
Sbjct: 1501 SAEEPSAPYAHTRKSFSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSLSMRRLSRTSA 1560
Query: 1561 FQSFESKHN 1569
FQSFESKHN
Sbjct: 1561 FQSFESKHN 1569
>gi|154091308 transient receptor potential cation channel, subfamily
M, member 3 isoform f [Homo sapiens]
Length = 1579
Score = 3148 bits (8162), Expect = 0.0
Identities = 1569/1579 (99%), Positives = 1569/1579 (99%), Gaps = 10/1579 (0%)
Query: 1 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 60
MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT
Sbjct: 1 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 60
Query: 61 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 120
TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ
Sbjct: 61 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 120
Query: 121 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRCLPFFSLD 180
TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRCLPFFSLD
Sbjct: 121 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRCLPFFSLD 180
Query: 181 SRLFYSFWGSCQLDSVGIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRA 240
SRLFYSFWGSCQLDSVGIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRA
Sbjct: 181 SRLFYSFWGSCQLDSVGIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRA 240
Query: 241 SDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVF 300
SDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVF
Sbjct: 241 SDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVF 300
Query: 301 RMGSEGHQDIDLAILTALLKGANASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQ 360
RMGSEGHQDIDLAILTALLKGANASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQ
Sbjct: 301 RMGSEGHQDIDLAILTALLKGANASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQ 360
Query: 361 AMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLP 420
AMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLP
Sbjct: 361 AMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLP 420
Query: 421 PDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKR----------DDIPLRR 470
PDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKR DDIPLRR
Sbjct: 421 PDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPKALKLLGMEDDIPLRR 480
Query: 471 GRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALV 530
GRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALV
Sbjct: 481 GRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALV 540
Query: 531 ACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELK 590
ACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELK
Sbjct: 541 ACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELK 600
Query: 591 NWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSL 650
NWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSL
Sbjct: 601 NWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSL 660
Query: 651 EFKNKDDMPYMSQAQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEE 710
EFKNKDDMPYMSQAQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEE
Sbjct: 661 EFKNKDDMPYMSQAQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEE 720
Query: 711 VQSKHRLIPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVIS 770
VQSKHRLIPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVIS
Sbjct: 721 VQSKHRLIPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVIS 780
Query: 771 YIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSD 830
YIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSD
Sbjct: 781 YIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSD 840
Query: 831 GRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQA 890
GRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQA
Sbjct: 841 GRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQA 900
Query: 891 ILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWI 950
ILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWI
Sbjct: 901 ILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWI 960
Query: 951 VPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPL 1010
VPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPL
Sbjct: 961 VPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPL 1020
Query: 1011 IIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDD 1070
IIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDD
Sbjct: 1021 IIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDD 1080
Query: 1071 RFNSSNDERIRVTSERVENMSMRLEEVNEREHSMKASLQTVDIRLAQLEDLIGRMATALE 1130
RFNSSNDERIRVTSERVENMSMRLEEVNEREHSMKASLQTVDIRLAQLEDLIGRMATALE
Sbjct: 1081 RFNSSNDERIRVTSERVENMSMRLEEVNEREHSMKASLQTVDIRLAQLEDLIGRMATALE 1140
Query: 1131 RLTGLERAESNKIRSRTSSDCTDAAYIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSP 1190
RLTGLERAESNKIRSRTSSDCTDAAYIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSP
Sbjct: 1141 RLTGLERAESNKIRSRTSSDCTDAAYIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSP 1200
Query: 1191 TLMPRMRSHSFYSVNMKDKGGIEKLESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLA 1250
TLMPRMRSHSFYSVNMKDKGGIEKLESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLA
Sbjct: 1201 TLMPRMRSHSFYSVNMKDKGGIEKLESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLA 1260
Query: 1251 IVPDSRRPSSCIDIYVSAMDELHCDIDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATL 1310
IVPDSRRPSSCIDIYVSAMDELHCDIDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATL
Sbjct: 1261 IVPDSRRPSSCIDIYVSAMDELHCDIDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATL 1320
Query: 1311 APTDRPPSRSIDFEDITSMDTRSFSSDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATT 1370
APTDRPPSRSIDFEDITSMDTRSFSSDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATT
Sbjct: 1321 APTDRPPSRSIDFEDITSMDTRSFSSDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATT 1380
Query: 1371 PFLLEEAPIVKSHSFMFSPSRSYYANFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAF 1430
PFLLEEAPIVKSHSFMFSPSRSYYANFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAF
Sbjct: 1381 PFLLEEAPIVKSHSFMFSPSRSYYANFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAF 1440
Query: 1431 PGGLGDKVEDLTCCHPEREAELSHPSSDSEENEAKGRRATIAISSQEGDNSERTLSNNIT 1490
PGGLGDKVEDLTCCHPEREAELSHPSSDSEENEAKGRRATIAISSQEGDNSERTLSNNIT
Sbjct: 1441 PGGLGDKVEDLTCCHPEREAELSHPSSDSEENEAKGRRATIAISSQEGDNSERTLSNNIT 1500
Query: 1491 VPKIERANSYSAEEPSAPYAHTRKSFSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSL 1550
VPKIERANSYSAEEPSAPYAHTRKSFSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSL
Sbjct: 1501 VPKIERANSYSAEEPSAPYAHTRKSFSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSL 1560
Query: 1551 SMRRLSRTSAFQSFESKHN 1569
SMRRLSRTSAFQSFESKHN
Sbjct: 1561 SMRRLSRTSAFQSFESKHN 1579
>gi|154091318 transient receptor potential cation channel, subfamily
M, member 3 isoform d [Homo sapiens]
Length = 1544
Score = 3088 bits (8006), Expect = 0.0
Identities = 1544/1569 (98%), Positives = 1544/1569 (98%), Gaps = 25/1569 (1%)
Query: 1 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 60
MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT
Sbjct: 1 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 60
Query: 61 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 120
TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ
Sbjct: 61 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 120
Query: 121 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRCLPFFSLD 180
TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTR
Sbjct: 121 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTR-------- 172
Query: 181 SRLFYSFWGSCQLDSVGIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRA 240
IGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRA
Sbjct: 173 -----------------IGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRA 215
Query: 241 SDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVF 300
SDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVF
Sbjct: 216 SDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVF 275
Query: 301 RMGSEGHQDIDLAILTALLKGANASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQ 360
RMGSEGHQDIDLAILTALLKGANASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQ
Sbjct: 276 RMGSEGHQDIDLAILTALLKGANASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQ 335
Query: 361 AMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLP 420
AMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLP
Sbjct: 336 AMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLP 395
Query: 421 PDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRDDIPLRRGRKTTKKREE 480
PDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRDDIPLRRGRKTTKKREE
Sbjct: 396 PDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRDDIPLRRGRKTTKKREE 455
Query: 481 EVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAH 540
EVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAH
Sbjct: 456 EVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAH 515
Query: 541 EASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQL 600
EASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQL
Sbjct: 516 EASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQL 575
Query: 601 AVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPY 660
AVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPY
Sbjct: 576 AVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPY 635
Query: 661 MSQAQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPL 720
MSQAQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPL
Sbjct: 636 MSQAQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPL 695
Query: 721 GRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVISYIFTLGIEKM 780
GRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVISYIFTLGIEKM
Sbjct: 696 GRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVISYIFTLGIEKM 755
Query: 781 REILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSDGRVIYCVNII 840
REILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSDGRVIYCVNII
Sbjct: 756 REILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSDGRVIYCVNII 815
Query: 841 YWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSW 900
YWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSW
Sbjct: 816 YWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSW 875
Query: 901 KLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLL 960
KLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLL
Sbjct: 876 KLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLL 935
Query: 961 VANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIF 1020
VANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIF
Sbjct: 936 VANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIF 995
Query: 1021 QHLCCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERI 1080
QHLCCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERI
Sbjct: 996 QHLCCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERI 1055
Query: 1081 RVTSERVENMSMRLEEVNEREHSMKASLQTVDIRLAQLEDLIGRMATALERLTGLERAES 1140
RVTSERVENMSMRLEEVNEREHSMKASLQTVDIRLAQLEDLIGRMATALERLTGLERAES
Sbjct: 1056 RVTSERVENMSMRLEEVNEREHSMKASLQTVDIRLAQLEDLIGRMATALERLTGLERAES 1115
Query: 1141 NKIRSRTSSDCTDAAYIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSPTLMPRMRSHS 1200
NKIRSRTSSDCTDAAYIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSPTLMPRMRSHS
Sbjct: 1116 NKIRSRTSSDCTDAAYIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSPTLMPRMRSHS 1175
Query: 1201 FYSVNMKDKGGIEKLESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLAIVPDSRRPSS 1260
FYSVNMKDKGGIEKLESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLAIVPDSRRPSS
Sbjct: 1176 FYSVNMKDKGGIEKLESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLAIVPDSRRPSS 1235
Query: 1261 CIDIYVSAMDELHCDIDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATLAPTDRPPSRS 1320
CIDIYVSAMDELHCDIDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATLAPTDRPPSRS
Sbjct: 1236 CIDIYVSAMDELHCDIDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATLAPTDRPPSRS 1295
Query: 1321 IDFEDITSMDTRSFSSDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATTPFLLEEAPIV 1380
IDFEDITSMDTRSFSSDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATTPFLLEEAPIV
Sbjct: 1296 IDFEDITSMDTRSFSSDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATTPFLLEEAPIV 1355
Query: 1381 KSHSFMFSPSRSYYANFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAFPGGLGDKVED 1440
KSHSFMFSPSRSYYANFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAFPGGLGDKVED
Sbjct: 1356 KSHSFMFSPSRSYYANFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAFPGGLGDKVED 1415
Query: 1441 LTCCHPEREAELSHPSSDSEENEAKGRRATIAISSQEGDNSERTLSNNITVPKIERANSY 1500
LTCCHPEREAELSHPSSDSEENEAKGRRATIAISSQEGDNSERTLSNNITVPKIERANSY
Sbjct: 1416 LTCCHPEREAELSHPSSDSEENEAKGRRATIAISSQEGDNSERTLSNNITVPKIERANSY 1475
Query: 1501 SAEEPSAPYAHTRKSFSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSLSMRRLSRTSA 1560
SAEEPSAPYAHTRKSFSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSLSMRRLSRTSA
Sbjct: 1476 SAEEPSAPYAHTRKSFSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSLSMRRLSRTSA 1535
Query: 1561 FQSFESKHN 1569
FQSFESKHN
Sbjct: 1536 FQSFESKHN 1544
>gi|154091320 transient receptor potential cation channel, subfamily
M, member 3 isoform a [Homo sapiens]
Length = 1554
Score = 3080 bits (7985), Expect = 0.0
Identities = 1544/1579 (97%), Positives = 1544/1579 (97%), Gaps = 35/1579 (2%)
Query: 1 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 60
MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT
Sbjct: 1 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 60
Query: 61 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 120
TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ
Sbjct: 61 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 120
Query: 121 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRCLPFFSLD 180
TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTR
Sbjct: 121 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTR-------- 172
Query: 181 SRLFYSFWGSCQLDSVGIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRA 240
IGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRA
Sbjct: 173 -----------------IGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRA 215
Query: 241 SDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVF 300
SDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVF
Sbjct: 216 SDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVF 275
Query: 301 RMGSEGHQDIDLAILTALLKGANASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQ 360
RMGSEGHQDIDLAILTALLKGANASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQ
Sbjct: 276 RMGSEGHQDIDLAILTALLKGANASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQ 335
Query: 361 AMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLP 420
AMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLP
Sbjct: 336 AMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLP 395
Query: 421 PDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKR----------DDIPLRR 470
PDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKR DDIPLRR
Sbjct: 396 PDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPKALKLLGMEDDIPLRR 455
Query: 471 GRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALV 530
GRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALV
Sbjct: 456 GRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALV 515
Query: 531 ACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELK 590
ACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELK
Sbjct: 516 ACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELK 575
Query: 591 NWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSL 650
NWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSL
Sbjct: 576 NWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSL 635
Query: 651 EFKNKDDMPYMSQAQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEE 710
EFKNKDDMPYMSQAQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEE
Sbjct: 636 EFKNKDDMPYMSQAQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEE 695
Query: 711 VQSKHRLIPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVIS 770
VQSKHRLIPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVIS
Sbjct: 696 VQSKHRLIPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVIS 755
Query: 771 YIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSD 830
YIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSD
Sbjct: 756 YIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSD 815
Query: 831 GRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQA 890
GRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQA
Sbjct: 816 GRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQA 875
Query: 891 ILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWI 950
ILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWI
Sbjct: 876 ILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWI 935
Query: 951 VPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPL 1010
VPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPL
Sbjct: 936 VPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPL 995
Query: 1011 IIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDD 1070
IIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDD
Sbjct: 996 IIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDD 1055
Query: 1071 RFNSSNDERIRVTSERVENMSMRLEEVNEREHSMKASLQTVDIRLAQLEDLIGRMATALE 1130
RFNSSNDERIRVTSERVENMSMRLEEVNEREHSMKASLQTVDIRLAQLEDLIGRMATALE
Sbjct: 1056 RFNSSNDERIRVTSERVENMSMRLEEVNEREHSMKASLQTVDIRLAQLEDLIGRMATALE 1115
Query: 1131 RLTGLERAESNKIRSRTSSDCTDAAYIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSP 1190
RLTGLERAESNKIRSRTSSDCTDAAYIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSP
Sbjct: 1116 RLTGLERAESNKIRSRTSSDCTDAAYIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSP 1175
Query: 1191 TLMPRMRSHSFYSVNMKDKGGIEKLESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLA 1250
TLMPRMRSHSFYSVNMKDKGGIEKLESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLA
Sbjct: 1176 TLMPRMRSHSFYSVNMKDKGGIEKLESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLA 1235
Query: 1251 IVPDSRRPSSCIDIYVSAMDELHCDIDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATL 1310
IVPDSRRPSSCIDIYVSAMDELHCDIDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATL
Sbjct: 1236 IVPDSRRPSSCIDIYVSAMDELHCDIDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATL 1295
Query: 1311 APTDRPPSRSIDFEDITSMDTRSFSSDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATT 1370
APTDRPPSRSIDFEDITSMDTRSFSSDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATT
Sbjct: 1296 APTDRPPSRSIDFEDITSMDTRSFSSDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATT 1355
Query: 1371 PFLLEEAPIVKSHSFMFSPSRSYYANFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAF 1430
PFLLEEAPIVKSHSFMFSPSRSYYANFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAF
Sbjct: 1356 PFLLEEAPIVKSHSFMFSPSRSYYANFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAF 1415
Query: 1431 PGGLGDKVEDLTCCHPEREAELSHPSSDSEENEAKGRRATIAISSQEGDNSERTLSNNIT 1490
PGGLGDKVEDLTCCHPEREAELSHPSSDSEENEAKGRRATIAISSQEGDNSERTLSNNIT
Sbjct: 1416 PGGLGDKVEDLTCCHPEREAELSHPSSDSEENEAKGRRATIAISSQEGDNSERTLSNNIT 1475
Query: 1491 VPKIERANSYSAEEPSAPYAHTRKSFSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSL 1550
VPKIERANSYSAEEPSAPYAHTRKSFSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSL
Sbjct: 1476 VPKIERANSYSAEEPSAPYAHTRKSFSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSL 1535
Query: 1551 SMRRLSRTSAFQSFESKHN 1569
SMRRLSRTSAFQSFESKHN
Sbjct: 1536 SMRRLSRTSAFQSFESKHN 1554
>gi|154091314 transient receptor potential cation channel, subfamily
M, member 3 isoform k [Homo sapiens]
Length = 1707
Score = 3080 bits (7985), Expect = 0.0
Identities = 1544/1579 (97%), Positives = 1544/1579 (97%), Gaps = 35/1579 (2%)
Query: 1 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 60
MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT
Sbjct: 154 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 213
Query: 61 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 120
TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ
Sbjct: 214 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 273
Query: 121 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRCLPFFSLD 180
TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTR
Sbjct: 274 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTR-------- 325
Query: 181 SRLFYSFWGSCQLDSVGIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRA 240
IGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRA
Sbjct: 326 -----------------IGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRA 368
Query: 241 SDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVF 300
SDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVF
Sbjct: 369 SDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVF 428
Query: 301 RMGSEGHQDIDLAILTALLKGANASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQ 360
RMGSEGHQDIDLAILTALLKGANASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQ
Sbjct: 429 RMGSEGHQDIDLAILTALLKGANASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQ 488
Query: 361 AMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLP 420
AMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLP
Sbjct: 489 AMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLP 548
Query: 421 PDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKR----------DDIPLRR 470
PDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKR DDIPLRR
Sbjct: 549 PDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPKALKLLGMEDDIPLRR 608
Query: 471 GRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALV 530
GRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALV
Sbjct: 609 GRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALV 668
Query: 531 ACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELK 590
ACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELK
Sbjct: 669 ACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELK 728
Query: 591 NWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSL 650
NWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSL
Sbjct: 729 NWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSL 788
Query: 651 EFKNKDDMPYMSQAQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEE 710
EFKNKDDMPYMSQAQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEE
Sbjct: 789 EFKNKDDMPYMSQAQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEE 848
Query: 711 VQSKHRLIPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVIS 770
VQSKHRLIPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVIS
Sbjct: 849 VQSKHRLIPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVIS 908
Query: 771 YIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSD 830
YIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSD
Sbjct: 909 YIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSD 968
Query: 831 GRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQA 890
GRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQA
Sbjct: 969 GRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQA 1028
Query: 891 ILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWI 950
ILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWI
Sbjct: 1029 ILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWI 1088
Query: 951 VPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPL 1010
VPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPL
Sbjct: 1089 VPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPL 1148
Query: 1011 IIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDD 1070
IIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDD
Sbjct: 1149 IIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDD 1208
Query: 1071 RFNSSNDERIRVTSERVENMSMRLEEVNEREHSMKASLQTVDIRLAQLEDLIGRMATALE 1130
RFNSSNDERIRVTSERVENMSMRLEEVNEREHSMKASLQTVDIRLAQLEDLIGRMATALE
Sbjct: 1209 RFNSSNDERIRVTSERVENMSMRLEEVNEREHSMKASLQTVDIRLAQLEDLIGRMATALE 1268
Query: 1131 RLTGLERAESNKIRSRTSSDCTDAAYIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSP 1190
RLTGLERAESNKIRSRTSSDCTDAAYIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSP
Sbjct: 1269 RLTGLERAESNKIRSRTSSDCTDAAYIVRQSSFNSQEGNTFKLQESIDPAGEETMSPTSP 1328
Query: 1191 TLMPRMRSHSFYSVNMKDKGGIEKLESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLA 1250
TLMPRMRSHSFYSVNMKDKGGIEKLESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLA
Sbjct: 1329 TLMPRMRSHSFYSVNMKDKGGIEKLESIFKERSLSLHRATSSHSVAKEPKAPAAPANTLA 1388
Query: 1251 IVPDSRRPSSCIDIYVSAMDELHCDIDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATL 1310
IVPDSRRPSSCIDIYVSAMDELHCDIDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATL
Sbjct: 1389 IVPDSRRPSSCIDIYVSAMDELHCDIDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYATL 1448
Query: 1311 APTDRPPSRSIDFEDITSMDTRSFSSDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATT 1370
APTDRPPSRSIDFEDITSMDTRSFSSDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATT
Sbjct: 1449 APTDRPPSRSIDFEDITSMDTRSFSSDYTHLPECQNPWDSEPPMYHTIERSKSSRYLATT 1508
Query: 1371 PFLLEEAPIVKSHSFMFSPSRSYYANFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAF 1430
PFLLEEAPIVKSHSFMFSPSRSYYANFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAF
Sbjct: 1509 PFLLEEAPIVKSHSFMFSPSRSYYANFGVPVKTAEYTSITDCIDTRCVNAPQAIADRAAF 1568
Query: 1431 PGGLGDKVEDLTCCHPEREAELSHPSSDSEENEAKGRRATIAISSQEGDNSERTLSNNIT 1490
PGGLGDKVEDLTCCHPEREAELSHPSSDSEENEAKGRRATIAISSQEGDNSERTLSNNIT
Sbjct: 1569 PGGLGDKVEDLTCCHPEREAELSHPSSDSEENEAKGRRATIAISSQEGDNSERTLSNNIT 1628
Query: 1491 VPKIERANSYSAEEPSAPYAHTRKSFSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSL 1550
VPKIERANSYSAEEPSAPYAHTRKSFSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSL
Sbjct: 1629 VPKIERANSYSAEEPSAPYAHTRKSFSISDKLDRQRNTASLRNPFQRSKSSKPEGRGDSL 1688
Query: 1551 SMRRLSRTSAFQSFESKHN 1569
SMRRLSRTSAFQSFESKHN
Sbjct: 1689 SMRRLSRTSAFQSFESKHN 1707
>gi|154091316 transient receptor potential cation channel, subfamily
M, member 3 isoform e [Homo sapiens]
Length = 1556
Score = 3079 bits (7983), Expect = 0.0
Identities = 1544/1581 (97%), Positives = 1544/1581 (97%), Gaps = 37/1581 (2%)
Query: 1 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 60
MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT
Sbjct: 1 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 60
Query: 61 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 120
TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ
Sbjct: 61 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 120
Query: 121 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRCLPFFSLD 180
TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTR
Sbjct: 121 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTR-------- 172
Query: 181 SRLFYSFWGSCQLDSVGIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRA 240
IGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRA
Sbjct: 173 -----------------IGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRA 215
Query: 241 SDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVF 300
SDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVF
Sbjct: 216 SDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVF 275
Query: 301 RMGSEGHQDIDLAILTALLKGANASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQ 360
RMGSEGHQDIDLAILTALLKGANASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQ
Sbjct: 276 RMGSEGHQDIDLAILTALLKGANASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQ 335
Query: 361 AMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKK---- 416
AMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKK
Sbjct: 336 AMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKREYP 395
Query: 417 --------GNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRDDIPL 468
GNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRDDIPL
Sbjct: 396 GFGWIYFKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRDDIPL 455
Query: 469 RRGRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKA 528
RRGRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKA
Sbjct: 456 RRGRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKA 515
Query: 529 LVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYE 588
LVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYE
Sbjct: 516 LVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYE 575
Query: 589 LKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSIL 648
LKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSIL
Sbjct: 576 LKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSIL 635
Query: 649 SLEFKNKDDMPYMSQAQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDE 708
SLEFKNKDDMPYMSQAQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDE
Sbjct: 636 SLEFKNKDDMPYMSQAQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDE 695
Query: 709 EEVQSKHRLIPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIV 768
EEVQSKHRLIPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIV
Sbjct: 696 EEVQSKHRLIPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIV 755
Query: 769 ISYIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFR 828
ISYIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFR
Sbjct: 756 ISYIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFR 815
Query: 829 SDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVAR 888
SDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVAR
Sbjct: 816 SDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVAR 875
Query: 889 QAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGA 948
QAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGA
Sbjct: 876 QAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGA 935
Query: 949 WIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPP 1008
WIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPP
Sbjct: 936 WIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPP 995
Query: 1009 PLIIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEEYFREK 1068
PLIIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEEYFREK
Sbjct: 996 PLIIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEEYFREK 1055
Query: 1069 DDRFNSSNDERIRVTSERVENMSMRLEEVNEREHSMKASLQTVDIRLAQLEDLIGRMATA 1128
DDRFNSSNDERIRVTSERVENMSMRLEEVNEREHSMKASLQTVDIRLAQLEDLIGRMATA
Sbjct: 1056 DDRFNSSNDERIRVTSERVENMSMRLEEVNEREHSMKASLQTVDIRLAQLEDLIGRMATA 1115
Query: 1129 LERLTGLERAESNKIRSRTSSDCTDAAYIVRQSSFNSQEGNTFKLQESIDPAGEETMSPT 1188
LERLTGLERAESNKIRSRTSSDCTDAAYIVRQSSFNSQEGNTFKLQESIDPAGEETMSPT
Sbjct: 1116 LERLTGLERAESNKIRSRTSSDCTDAAYIVRQSSFNSQEGNTFKLQESIDPAGEETMSPT 1175
Query: 1189 SPTLMPRMRSHSFYSVNMKDKGGIEKLESIFKERSLSLHRATSSHSVAKEPKAPAAPANT 1248
SPTLMPRMRSHSFYSVNMKDKGGIEKLESIFKERSLSLHRATSSHSVAKEPKAPAAPANT
Sbjct: 1176 SPTLMPRMRSHSFYSVNMKDKGGIEKLESIFKERSLSLHRATSSHSVAKEPKAPAAPANT 1235
Query: 1249 LAIVPDSRRPSSCIDIYVSAMDELHCDIDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYA 1308
LAIVPDSRRPSSCIDIYVSAMDELHCDIDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYA
Sbjct: 1236 LAIVPDSRRPSSCIDIYVSAMDELHCDIDPLDNSVNILGLGEPSFSTPVPSTAPSSSAYA 1295
Query: 1309 TLAPTDRPPSRSIDFEDITSMDTRSFSSDYTHLPECQNPWDSEPPMYHTIERSKSSRYLA 1368
TLAPTDRPPSRSIDFEDITSMDTRSFSSDYTHLPECQNPWDSEPPMYHTIERSKSSRYLA
Sbjct: 1296 TLAPTDRPPSRSIDFEDITSMDTRSFSSDYTHLPECQNPWDSEPPMYHTIERSKSSRYLA 1355
Query: 1369 TTPFLLEEAPIVKSHSFMFSPSRSYYANFGVPVKTAEYTSITDCIDTRCVNAPQAIADRA 1428
TTPFLLEEAPIVKSHSFMFSPSRSYYANFGVPVKTAEYTSITDCIDTRCVNAPQAIADRA
Sbjct: 1356 TTPFLLEEAPIVKSHSFMFSPSRSYYANFGVPVKTAEYTSITDCIDTRCVNAPQAIADRA 1415
Query: 1429 AFPGGLGDKVEDLTCCHPEREAELSHPSSDSEENEAKGRRATIAISSQEGDNSERTLSNN 1488
AFPGGLGDKVEDLTCCHPEREAELSHPSSDSEENEAKGRRATIAISSQEGDNSERTLSNN
Sbjct: 1416 AFPGGLGDKVEDLTCCHPEREAELSHPSSDSEENEAKGRRATIAISSQEGDNSERTLSNN 1475
Query: 1489 ITVPKIERANSYSAEEPSAPYAHTRKSFSISDKLDRQRNTASLRNPFQRSKSSKPEGRGD 1548
ITVPKIERANSYSAEEPSAPYAHTRKSFSISDKLDRQRNTASLRNPFQRSKSSKPEGRGD
Sbjct: 1476 ITVPKIERANSYSAEEPSAPYAHTRKSFSISDKLDRQRNTASLRNPFQRSKSSKPEGRGD 1535
Query: 1549 SLSMRRLSRTSAFQSFESKHN 1569
SLSMRRLSRTSAFQSFESKHN
Sbjct: 1536 SLSMRRLSRTSAFQSFESKHN 1556
>gi|154091312 transient receptor potential cation channel, subfamily
M, member 3 isoform b [Homo sapiens]
Length = 1566
Score = 3071 bits (7962), Expect = 0.0
Identities = 1544/1591 (97%), Positives = 1544/1591 (97%), Gaps = 47/1591 (2%)
Query: 1 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 60
MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT
Sbjct: 1 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 60
Query: 61 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 120
TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ
Sbjct: 61 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 120
Query: 121 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRCLPFFSLD 180
TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTR
Sbjct: 121 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTR-------- 172
Query: 181 SRLFYSFWGSCQLDSVGIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRA 240
IGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRA
Sbjct: 173 -----------------IGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRA 215
Query: 241 SDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVF 300
SDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVF
Sbjct: 216 SDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVF 275
Query: 301 RMGSEGHQDIDLAILTALLKGANASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQ 360
RMGSEGHQDIDLAILTALLKGANASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQ
Sbjct: 276 RMGSEGHQDIDLAILTALLKGANASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQ 335
Query: 361 AMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKK---- 416
AMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKK
Sbjct: 336 AMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKREYP 395
Query: 417 --------GNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKR----- 463
GNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKR
Sbjct: 396 GFGWIYFKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPKALK 455
Query: 464 -----DDIPLRRGRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFW 518
DDIPLRRGRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFW
Sbjct: 456 LLGMEDDIPLRRGRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFW 515
Query: 519 QHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDE 578
QHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDE
Sbjct: 516 QHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDE 575
Query: 579 QLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVI 638
QLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVI
Sbjct: 576 QLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVI 635
Query: 639 LGILLPPSILSLEFKNKDDMPYMSQAQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRN 698
LGILLPPSILSLEFKNKDDMPYMSQAQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRN
Sbjct: 636 LGILLPPSILSLEFKNKDDMPYMSQAQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRN 695
Query: 699 NGESSRKKDEEEVQSKHRLIPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKME 758
NGESSRKKDEEEVQSKHRLIPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKME
Sbjct: 696 NGESSRKKDEEEVQSKHRLIPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKME 755
Query: 759 RWPSTQEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGM 818
RWPSTQEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGM
Sbjct: 756 RWPSTQEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGM 815
Query: 819 ILRLQDQPFRSDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIML 878
ILRLQDQPFRSDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIML
Sbjct: 816 ILRLQDQPFRSDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIML 875
Query: 879 VVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKI 938
VVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKI
Sbjct: 876 VVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKI 935
Query: 939 IQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIM 998
IQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIM
Sbjct: 936 IQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIM 995
Query: 999 TFHERPVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITDDELKKVHDFEE 1058
TFHERPVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITDDELKKVHDFEE
Sbjct: 996 TFHERPVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITDDELKKVHDFEE 1055
Query: 1059 QCIEEYFREKDDRFNSSNDERIRVTSERVENMSMRLEEVNEREHSMKASLQTVDIRLAQL 1118
QCIEEYFREKDDRFNSSNDERIRVTSERVENMSMRLEEVNEREHSMKASLQTVDIRLAQL
Sbjct: 1056 QCIEEYFREKDDRFNSSNDERIRVTSERVENMSMRLEEVNEREHSMKASLQTVDIRLAQL 1115
Query: 1119 EDLIGRMATALERLTGLERAESNKIRSRTSSDCTDAAYIVRQSSFNSQEGNTFKLQESID 1178
EDLIGRMATALERLTGLERAESNKIRSRTSSDCTDAAYIVRQSSFNSQEGNTFKLQESID
Sbjct: 1116 EDLIGRMATALERLTGLERAESNKIRSRTSSDCTDAAYIVRQSSFNSQEGNTFKLQESID 1175
Query: 1179 PAGEETMSPTSPTLMPRMRSHSFYSVNMKDKGGIEKLESIFKERSLSLHRATSSHSVAKE 1238
PAGEETMSPTSPTLMPRMRSHSFYSVNMKDKGGIEKLESIFKERSLSLHRATSSHSVAKE
Sbjct: 1176 PAGEETMSPTSPTLMPRMRSHSFYSVNMKDKGGIEKLESIFKERSLSLHRATSSHSVAKE 1235
Query: 1239 PKAPAAPANTLAIVPDSRRPSSCIDIYVSAMDELHCDIDPLDNSVNILGLGEPSFSTPVP 1298
PKAPAAPANTLAIVPDSRRPSSCIDIYVSAMDELHCDIDPLDNSVNILGLGEPSFSTPVP
Sbjct: 1236 PKAPAAPANTLAIVPDSRRPSSCIDIYVSAMDELHCDIDPLDNSVNILGLGEPSFSTPVP 1295
Query: 1299 STAPSSSAYATLAPTDRPPSRSIDFEDITSMDTRSFSSDYTHLPECQNPWDSEPPMYHTI 1358
STAPSSSAYATLAPTDRPPSRSIDFEDITSMDTRSFSSDYTHLPECQNPWDSEPPMYHTI
Sbjct: 1296 STAPSSSAYATLAPTDRPPSRSIDFEDITSMDTRSFSSDYTHLPECQNPWDSEPPMYHTI 1355
Query: 1359 ERSKSSRYLATTPFLLEEAPIVKSHSFMFSPSRSYYANFGVPVKTAEYTSITDCIDTRCV 1418
ERSKSSRYLATTPFLLEEAPIVKSHSFMFSPSRSYYANFGVPVKTAEYTSITDCIDTRCV
Sbjct: 1356 ERSKSSRYLATTPFLLEEAPIVKSHSFMFSPSRSYYANFGVPVKTAEYTSITDCIDTRCV 1415
Query: 1419 NAPQAIADRAAFPGGLGDKVEDLTCCHPEREAELSHPSSDSEENEAKGRRATIAISSQEG 1478
NAPQAIADRAAFPGGLGDKVEDLTCCHPEREAELSHPSSDSEENEAKGRRATIAISSQEG
Sbjct: 1416 NAPQAIADRAAFPGGLGDKVEDLTCCHPEREAELSHPSSDSEENEAKGRRATIAISSQEG 1475
Query: 1479 DNSERTLSNNITVPKIERANSYSAEEPSAPYAHTRKSFSISDKLDRQRNTASLRNPFQRS 1538
DNSERTLSNNITVPKIERANSYSAEEPSAPYAHTRKSFSISDKLDRQRNTASLRNPFQRS
Sbjct: 1476 DNSERTLSNNITVPKIERANSYSAEEPSAPYAHTRKSFSISDKLDRQRNTASLRNPFQRS 1535
Query: 1539 KSSKPEGRGDSLSMRRLSRTSAFQSFESKHN 1569
KSSKPEGRGDSLSMRRLSRTSAFQSFESKHN
Sbjct: 1536 KSSKPEGRGDSLSMRRLSRTSAFQSFESKHN 1566
>gi|148612863 transient receptor potential cation channel, subfamily
M, member 7 [Homo sapiens]
Length = 1865
Score = 1354 bits (3504), Expect = 0.0
Identities = 684/1217 (56%), Positives = 888/1217 (72%), Gaps = 107/1217 (8%)
Query: 2 YVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTT 61
YVR+S+DTKP+++L L+ KEWQ+ELPKL+ISVHGG+Q FEL P++KQ+ GKGLIKAA+TT
Sbjct: 108 YVRLSYDTKPEVILQLLLKEWQMELPKLVISVHGGMQKFELHPRIKQLLGKGLIKAAVTT 167
Query: 62 GAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQT 121
GAWI TGGVNTGV +HVGDALK+HAS+S KICTIGIAPWG++EN+ DL+GRDVV PYQT
Sbjct: 168 GAWILTGGVNTGVAKHVGDALKEHASRSSRKICTIGIAPWGVIENRNDLVGRDVVAPYQT 227
Query: 122 MSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRCLPFFSLDS 181
+ NP+SKL VLN++HSHFIL D+GT GKYGAEV+LRR+LEK I+ Q+I+ R
Sbjct: 228 LLNPLSKLNVLNNLHSHFILVDDGTVGKYGAEVRLRRELEKTINQQRIHAR--------- 278
Query: 182 RLFYSFWGSCQLDSVGIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRAS 241
IGQGVPVVALI EGGPNVI VLEYL+++PPVPVVVC+G+GRA+
Sbjct: 279 ----------------IGQGVPVVALIFEGGPNVILTVLEYLQESPPVPVVVCEGTGRAA 322
Query: 242 DILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFR 301
D+LA+ HK +EEGG + ++ ++ TI+KTF + + +A HLF LMECMK+KELITVF
Sbjct: 323 DLLAYIHKQTEEGGNLPDAAEPDIISTIKKTFNFGQNEALHLFQTLMECMKRKELITVFH 382
Query: 302 MGSEGHQDIDLAILTALLKGANASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQA 361
+GS+ HQDID+AILTALLKG NASA DQL L LAW+RVDIA++ +F+YGQQW VGSLEQA
Sbjct: 383 IGSDEHQDIDVAILTALLKGTNASAFDQLILTLAWDRVDIAKNHVFVYGQQWLVGSLEQA 442
Query: 362 MLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNT-LYHLVRDVKKGNLP 420
MLDALV+DRV FVKLLIENGVSMH+FLTI RLEELYNT+ GP+N L+HLVRDVK+GNLP
Sbjct: 443 MLDALVMDRVAFVKLLIENGVSMHKFLTIPRLEELYNTKQGPTNPMLFHLVRDVKQGNLP 502
Query: 421 PDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRDDIPLRRGRKTT----- 475
P Y+I+LIDIGLVIEYLMGG YRC YTRKRFR +Y++L G R R GR T+
Sbjct: 503 PGYKITLIDIGLVIEYLMGGTYRCTYTRKRFRLIYNSLGGNNR-----RSGRNTSSSTPQ 557
Query: 476 ------------------------------------------KKREEEVDIDLDDPEINH 493
KKR ++ +D+DDPE
Sbjct: 558 LRKSHESFGNRADKKEKMRHNHFIKTAQPYRPKIDTVMEEGKKKRTKDEIVDIDDPETKR 617
Query: 494 FPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQ 553
FP+P +EL++WA LMKRQ MA F WQHGEE+MAKALVACK+ ++MA+EA ++D+VDD S+
Sbjct: 618 FPYPLNELLIWACLMKRQVMARFLWQHGEESMAKALVACKIYRSMAYEAKQSDLVDDTSE 677
Query: 554 ELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHT 613
EL S DFGQLAVELL+QS++QDE +AMKLLTYELKNWSN+TCL+LAV+++ R F+AHT
Sbjct: 678 ELKQYSNDFGQLAVELLEQSFRQDETMAMKLLTYELKNWSNSTCLKLAVSSRLRPFVAHT 737
Query: 614 CSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMSQAQEIHLQEKE 673
C+QMLL+DMWMGRL MRKNS KVIL IL+PP+IL LE+K K +M ++ Q+Q+ H +
Sbjct: 738 CTQMLLSDMWMGRLNMRKNSWYKVILSILVPPAILLLEYKTKAEMSHIPQSQDAHQMTMD 797
Query: 674 AEEP--EKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPLGRKIYEFYNAP 731
E + T+E E + +L N G K+E E+Q K + +P+ RK Y FY+AP
Sbjct: 798 DSENNFQNITEEIPMEVFKEVRILDSNEG-----KNEMEIQMKSKKLPITRKFYAFYHAP 852
Query: 732 IVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVISYIFTLGIEKMREILMSEPGKL 791
IVKFWF TLAY+G+LML+ ++VLV+ME+ PS QEWIVI+YIFT IEK+REI MSE GK+
Sbjct: 853 IVKFWFNTLAYLGFLMLYTFVVLVQMEQLPSVQEWIVIAYIFTYAIEKVREIFMSEAGKV 912
Query: 792 LQKVKVWLQEYWNVTDLIAILLFSVGMILRL---------QDQPFRSDGRVIYCVNIIYW 842
QK+KVW +Y+N++D IAI+ F +G LR D GR+IYC+NII+W
Sbjct: 913 NQKIKVWFSDYFNISDTIAIISFFIGFGLRFGAKWNFANAYDNHVFVAGRLIYCLNIIFW 972
Query: 843 YIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKL 902
Y+RLLD VN+ GPYVMMIGKM+ +M Y V+IM +VL+SFGV R+AIL+P+E PSW L
Sbjct: 973 YVRLLDFLAVNQQAGPYVMMIGKMVANMFYIVVIMALVLLSFGVPRKAILYPHEAPSWTL 1032
Query: 903 AKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVA 962
AK+I + PYWMI+GEV+A +ID D I Q+ C G W+ P + A YL V
Sbjct: 1033 AKDIVFHPYWMIFGEVYAYEID------VCANDSVIPQI--CGPGTWLTPFLQAVYLFVQ 1084
Query: 963 NILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQH 1022
I++VNLLIA FNN + +VK+ISN VWK+QRY IM +HE+PVLPPPLII SH+ +F
Sbjct: 1085 YIIMVNLLIAFFNNVYLQVKAISNIVWKYQRYHFIMAYHEKPVLPPPLIILSHIVSLFCC 1144
Query: 1023 LCCRWRKHESDPDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRV 1082
+C R +K D+ G KLF+T+++ KK+HDFEEQC+E YF EKDD+F+S ++ERIRV
Sbjct: 1145 ICKRRKK-----DKTSDGPKLFLTEEDQKKLHDFEEQCVEMYFNEKDDKFHSGSEERIRV 1199
Query: 1083 TSERVENMSMRLEEVNEREHSMKASLQTVDIRLAQLEDLIGRMATALERLTGLERAESNK 1142
T ERVE M ++++EV +R + +K SLQ++D ++ L+DL L+ LT + +E++K
Sbjct: 1200 TFERVEQMCIQIKEVGDRVNYIKRSLQSLDSQIGHLQDLSALTVDTLKTLTAQKASEASK 1259
Query: 1143 IRSRTSSDCTDAAYIVR 1159
+ + + + + + ++ +
Sbjct: 1260 VHNEITRELSISKHLAQ 1276
>gi|18921093 transient receptor potential cation channel, subfamily M,
member 6 [Homo sapiens]
Length = 2022
Score = 1252 bits (3240), Expect = 0.0
Identities = 638/1188 (53%), Positives = 845/1188 (71%), Gaps = 90/1188 (7%)
Query: 2 YVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTT 61
Y+R S+DTK D LLHLM KEW++ELPKL+ISVHGG+QNF + K K++F +GL+KAA TT
Sbjct: 111 YIRTSYDTKLDHLLHLMLKEWKMELPKLVISVHGGIQNFTMPSKFKEIFSQGLVKAAETT 170
Query: 62 GAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQT 121
GAWI T G+NTGV +HVGDALK H+S S KI T+GI PWG++ENQ DLIG+DVV YQT
Sbjct: 171 GAWIITEGINTGVSKHVGDALKSHSSHSLRKIWTVGIPPWGVIENQRDLIGKDVVCLYQT 230
Query: 122 MSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRCLPFFSLDS 181
+ NP+SKLT LNSMHSHFIL+D+GT GKYG E+KLRR LEK++SLQKI+ R S
Sbjct: 231 LDNPLSKLTTLNSMHSHFILSDDGTVGKYGNEMKLRRNLEKYLSLQKIHCR--------S 282
Query: 182 RLFYSFWGSCQLDSVGIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRAS 241
R QGVPVV L+VEGGPNVI V E ++D PV VVC+G+GRA+
Sbjct: 283 R-----------------QGVPVVGLVVEGGPNVILSVWETVKDKDPV--VVCEGTGRAA 323
Query: 242 DILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFR 301
D+LAF HK+ + G++ ++++++ IQ TF ++ Q++HLF ILMECM ++ IT+F
Sbjct: 324 DLLAFTHKHLADEGMLRPQVKEEIICMIQNTFNFSLKQSKHLFQILMECMVHRDCITIFD 383
Query: 302 MGSEGHQDIDLAILTALLKGANASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQA 361
SE QD+DLAILTALLKG N SA +QL+LA+AW+RVDIA+ I IY Q W +LEQA
Sbjct: 384 ADSEEQQDLDLAILTALLKGTNLSASEQLNLAMAWDRVDIAKKHILIYEQHWKPDALEQA 443
Query: 362 MLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTL-YHLVRDVKKGNLP 420
M DALV+DRVDFVKLLIE GV++HRFLTI RLEELYNT+ GP+NTL +HLV+DVK+ L
Sbjct: 444 MSDALVMDRVDFVKLLIEYGVNLHRFLTIPRLEELYNTKQGPTNTLLHHLVQDVKQHTLL 503
Query: 421 PDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGP------------------- 461
YRI+LIDIGLV+EYL+G AYR NYTRK FR LY+NL+
Sbjct: 504 SGYRITLIDIGLVVEYLIGRAYRSNYTRKHFRALYNNLYRKYKHQRHSSGNRNESAESTL 563
Query: 462 -------------KRDDIPLRRGRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLM 508
K I L + RK K +E+ V DDPE F +P+++L+VWAVLM
Sbjct: 564 HSQFIRTAQPYKFKEKSIVLHKSRK--KSKEQNVS---DDPESTGFLYPYNDLLVWAVLM 618
Query: 509 KRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVE 568
KRQKMA+FFWQHGEEA KA++AC L +AMAHEA E+ MVDD S+EL + S+ FGQLA++
Sbjct: 619 KRQKMAMFFWQHGEEATVKAVIACILYRAMAHEAKESHMVDDASEELKNYSKQFGQLALD 678
Query: 569 LLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLR 628
LL++++KQ+E++AM LLTYEL+NWSN+TCL+LAV+ R F++HTC+QMLLTDMWMGRL+
Sbjct: 679 LLEKAFKQNERMAMTLLTYELRNWSNSTCLKLAVSGGLRPFVSHTCTQMLLTDMWMGRLK 738
Query: 629 MRKNSGLKVILGILLPPSILSLEFKNKDDMPYMSQAQEIHLQEKEAEEPEKPTKEK---E 685
MRKNS LK+I+ I+LPP+IL+LEFK+K +M ++ Q+Q+ +++ +KE +
Sbjct: 739 MRKNSWLKIIISIILPPTILTLEFKSKAEMSHVPQSQDFQFMWYYSDQNASSSKESASVK 798
Query: 686 EEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPLGRKIYEFYNAPIVKFWFYTLAYIGY 745
E D+E R + E + ++S H+ +P RK+YEFY+APIVKFWFYT+AY+ +
Sbjct: 799 EYDLE------RGHDEKLDENQHFGLESGHQHLPWTRKVYEFYSAPIVKFWFYTMAYLAF 852
Query: 746 LMLFNYIVLVKMERWPSTQEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNV 805
LMLF Y VLV+M+ PS QEW+V YIFT IE +REI +SEPGK QKVKVW+ EYWN+
Sbjct: 853 LMLFTYTVLVEMQPQPSVQEWLVSIYIFTNAIEVVREICISEPGKFTQKVKVWISEYWNL 912
Query: 806 TDLIAILLFSVGMILRLQDQPFRSDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGK 865
T+ +AI LFS G +LR D PF + GR+IYC++II+W+ RLLD F VN++ GPYV MI K
Sbjct: 913 TETVAIGLFSAGFVLRWGDPPFHTAGRLIYCIDIIFWFSRLLDFFAVNQHAGPYVTMIAK 972
Query: 866 MMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDP 925
M +M Y VIIM +VL+SFGVAR+AIL P E PSW LA++I + PYWMIYGEV+A +ID
Sbjct: 973 MTANMFYIVIIMAIVLLSFGVARKAILSPKEPPSWSLARDIVFEPYWMIYGEVYAGEIDV 1032
Query: 926 PCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSIS 985
Q P C G+++ P + A YL V I++VNLLIA FNN + +++SIS
Sbjct: 1033 CSSQ------------PSCPPGSFLTPFLQAVYLFVQYIIMVNLLIAFFNNVYLDMESIS 1080
Query: 986 NQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFI 1045
N +WK+ RY+ IMT+HE+P LPPPLI+ SH+ ++ + LCC H D +E D GLKL++
Sbjct: 1081 NNLWKYNRYRYIMTYHEKPWLPPPLILLSHVGLLLRRLCCHRAPH--DQEEGDVGLKLYL 1138
Query: 1046 TDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVTSERVENMSMRLEEVNEREHSMK 1105
+ ++LKK+HDFEEQC+E+YF EK + N S +ERIRVTSERV M +L+E+NE+ +K
Sbjct: 1139 SKEDLKKLHDFEEQCVEKYFHEKMEDVNCSCEERIRVTSERVTEMYFQLKEMNEKVSFIK 1198
Query: 1106 ASLQTVDIRLAQLEDLIGRMATALERLTGLERAESNK--IRSRTSSDC 1151
SL ++D ++ L+DL L+ L+ ++ + ++ + R S C
Sbjct: 1199 DSLLSLDSQVGHLQDLSALTVDTLKVLSAVDTLQEDEALLAKRKHSTC 1246
>gi|94538366 transient receptor potential cation channel, subfamily M,
member 1 [Homo sapiens]
Length = 1603
Score = 1207 bits (3122), Expect = 0.0
Identities = 672/1204 (55%), Positives = 818/1204 (67%), Gaps = 112/1204 (9%)
Query: 355 VGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDV 414
V +LEQAMLDALVLDRVDFVKLLIENGV+M FLTI RLEELYNTR GP NTL+ LVRDV
Sbjct: 458 VNALEQAMLDALVLDRVDFVKLLIENGVNMQHFLTIPRLEELYNTRLGPPNTLHLLVRDV 517
Query: 415 KKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKR----------- 463
KK NLPPDY ISLIDIGLV+EYLMGGAYRCNYTRK FRTLY+NLFGPKR
Sbjct: 518 KKSNLPPDYHISLIDIGLVLEYLMGGAYRCNYTRKNFRTLYNNLFGPKRPKALKLLGMED 577
Query: 464 DDIPLRRGRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEE 523
D+ P + +K KK+EEE+DID+DDP ++ F +PFHELMVWAVLMKRQKMA+F WQ GEE
Sbjct: 578 DEPPAKGKKKKKKKKEEEIDIDVDDPAVSRFQYPFHELMVWAVLMKRQKMAVFLWQRGEE 637
Query: 524 AMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMK 583
+MAKALVACKL KAMAHE+SE+D+VDDISQ+L++NS+DFGQLA+ELLDQSYK DEQ+AMK
Sbjct: 638 SMAKALVACKLYKAMAHESSESDLVDDISQDLDNNSKDFGQLALELLDQSYKHDEQIAMK 697
Query: 584 LLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILL 643
LLTYELKNWSN+TCL+LAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKN GLKVI+GILL
Sbjct: 698 LLTYELKNWSNSTCLKLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNPGLKVIMGILL 757
Query: 644 PPSILSLEFKNKDDMPYMSQAQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESS 703
PP+IL LEF+ DD Y + KE E+ KEKEEE+ + A G S
Sbjct: 758 PPTILFLEFRTYDDFSYQTS--------KENEDG----KEKEEENTDANADAG------S 799
Query: 704 RKKDEEEVQSKHRLIPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPST 763
RK DEE K R IP+G KI EFYNAPIVKFWFYT++Y+GYL+LFNY++LV+M+ WPS
Sbjct: 800 RKGDEENEHKKQRSIPIGTKICEFYNAPIVKFWFYTISYLGYLLLFNYVILVRMDGWPSL 859
Query: 764 QEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQ 823
QEWIVISYI +L +EK+REILMSEPGKL QK+KVWLQEYWN+TDL+AI F +G ILRLQ
Sbjct: 860 QEWIVISYIVSLALEKIREILMSEPGKLSQKIKVWLQEYWNITDLVAISTFMIGAILRLQ 919
Query: 824 DQPFRSDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMS 883
+QP+ GRVIYCV+II+WYIR+LDIFGVNKYLGPYVMMIGKMMIDM+YFV+IMLVVLMS
Sbjct: 920 NQPYMGYGRVIYCVDIIFWYIRVLDIFGVNKYLGPYVMMIGKMMIDMLYFVVIMLVVLMS 979
Query: 884 FGVARQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQID-------PPCGQNETREDG 936
FGVARQAIL P E+PSWKLA+NIFYMPYWMIYGEVFADQID PPCG+N E+G
Sbjct: 980 FGVARQAILHPEEKPSWKLARNIFYMPYWMIYGEVFADQIDLYAMEINPPCGENLYDEEG 1039
Query: 937 KIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQL 996
K +LPPC GAW+ PA+MACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQL
Sbjct: 1040 K--RLPPCIPGAWLTPALMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQL 1097
Query: 997 IMTFHERPVLPPPLIIFSHMTMIFQHLCCRWR-KHESDPDERDYGLKLFITDDELKKVHD 1055
IMTFH+RPVLPPP+II SH+ +I L R R K E D +ERD GLKLF++D+ELK++H+
Sbjct: 1098 IMTFHDRPVLPPPMIILSHIYIIIMRLSGRCRKKREGDQEERDRGLKLFLSDEELKRLHE 1157
Query: 1056 FEEQCIEEYFREKDDRFNSSNDERIRVTSERVENMSMRLEEVNEREHSMKASLQTVDIRL 1115
FEEQC++E+FREK+D SS+DERIRVTSERVENMSMRLEE+NERE MK SLQTVD+RL
Sbjct: 1158 FEEQCVQEHFREKEDEQQSSSDERIRVTSERVENMSMRLEEINERETFMKTSLQTVDLRL 1217
Query: 1116 AQLEDLIGRMATALERLTGLERAESNKIRSRTSSDCTDAAYIVRQSSFNSQEGNT----- 1170
AQLE+L RM ALE L G++R++ + RSR SS+C +A Y++RQSS NS +G +
Sbjct: 1218 AQLEELSNRMVNALENLAGIDRSDLIQARSRASSEC-EATYLLRQSSINSADGYSLYRYH 1276
Query: 1171 FKLQESIDPAGEETMSPTSPTLMPRMRSHSFYSVNMKDKGGIEKLESIFKERSLSLHRAT 1230
F +E + E+T TSP R ++ SF KD + E SLH +
Sbjct: 1277 FNGEELL---FEDTSLSTSPGTGVRKKTCSFRIKEEKD-----VKTHLVPECQNSLHLSL 1328
Query: 1231 SSHSVAKEPKAPAAPANTLAIVPDSRRPSSCIDIYVSAMDELHCDIDPLDNSVNILGLGE 1290
+ + A PD H +D L N+ E
Sbjct: 1329 GTSTSA---------------TPDGS----------------HLAVDDLKNA-------E 1350
Query: 1291 PSFSTPVPSTAPSSSAYATLAPTDRPPSRSIDFEDITSMDTRSFSSDYTHLPECQNPWDS 1350
S P + T + + S S++ D+ +S + E N
Sbjct: 1351 ESKLGPDIGISKEDDERQTDSKKEETISPSLNKTDVIHGQDKSDVQNTQLTVETTN---I 1407
Query: 1351 EPPMYHTIERSKSSRYLATTPFLLEEAPIVKSHSFMFSPSRSYYANFGVPVKTAEYTSIT 1410
E + + +E +K +RY + +KS SF++S R V EY+SIT
Sbjct: 1408 EGTISYPLEETKITRYFPDE--TINACKTMKSRSFVYSRGRKLVGGVNQDV---EYSSIT 1462
Query: 1411 D---CIDTRCVNAPQAIADRAAFPGGLGDKVEDLTCCHPEREAELSHPSSDSEENEAKGR 1467
D + +C + P + E + + + + EA R
Sbjct: 1463 DQQLTTEWQCQVQKITRSHSTDIP-----YIVSEAAVQAEHKEQFADMQDEHHVAEAIPR 1517
Query: 1468 RATIAISSQEGDNSERTLSNNITVPKIERANSYSAEEPSAPYAHTRKSFSISDKLDRQRN 1527
++++ + + E LS K ++ + + + + H R SI KLDR +
Sbjct: 1518 IPRLSLTITDRNGMENLLS-----VKPDQTLGFPSLRSKSLHGHPRNVKSIQGKLDRSGH 1572
Query: 1528 TASL 1531
+S+
Sbjct: 1573 ASSV 1576
Score = 558 bits (1438), Expect = e-158
Identities = 274/359 (76%), Positives = 309/359 (86%), Gaps = 26/359 (7%)
Query: 1 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 60
MY+RVS+DTKPD LLHLM K+WQLELPKLLISVHGGLQNFE+QPKLKQVFGKGLIKAAMT
Sbjct: 71 MYIRVSYDTKPDSLLHLMVKDWQLELPKLLISVHGGLQNFEMQPKLKQVFGKGLIKAAMT 130
Query: 61 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 120
TGAWIFTGGV+TGVI HVGDALKDH+SKSRG++C IGIAPWGIVEN+EDL+G+DV R YQ
Sbjct: 131 TGAWIFTGGVSTGVISHVGDALKDHSSKSRGRVCAIGIAPWGIVENKEDLVGKDVTRVYQ 190
Query: 121 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRCLPFFSLD 180
TMSNP+SKL+VLN+ H+HFILADNGT GKYGAEVKLRR LEKHISLQKINTR
Sbjct: 191 TMSNPLSKLSVLNNSHTHFILADNGTLGKYGAEVKLRRLLEKHISLQKINTR-------- 242
Query: 181 SRLFYSFWGSCQLDSVGIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRA 240
+GQGVP+V L+VEGGPNV+SIVLEYL++ PP+PVV+CDGSGRA
Sbjct: 243 -----------------LGQGVPLVGLVVEGGPNVVSIVLEYLQEEPPIPVVICDGSGRA 285
Query: 241 SDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVF 300
SDIL+F HKY EEGG+INESLR+QLLVTIQKTF Y + Q+ LF I+MECMKKKEL+TVF
Sbjct: 286 SDILSFAHKYCEEGGIINESLREQLLVTIQKTFNYNKAQSHQLFAIIMECMKKKELVTVF 345
Query: 301 RMGSEGHQDIDLAILTALLKGANASAPDQLSLALAWNRVDIARSQIFIYGQQW-PVGSL 358
RMGSEG QDI++AILTALLKG N SAPDQLSLALAWNRVDIARSQIF++G W P+GSL
Sbjct: 346 RMGSEGQQDIEMAILTALLKGTNVSAPDQLSLALAWNRVDIARSQIFVFGPHWPPLGSL 404
>gi|4507689 transient receptor potential cation channel, subfamily M,
member 2 [Homo sapiens]
Length = 1503
Score = 521 bits (1341), Expect = e-147
Identities = 371/1175 (31%), Positives = 594/1175 (50%), Gaps = 154/1175 (13%)
Query: 2 YVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTT 61
YVRVS DT ++ HLMT+ W L++P LLISV GG +NF ++P+LK +F +GL+K A TT
Sbjct: 142 YVRVSQDTPSSVIYHLMTQHWGLDVPNLLISVTGGAKNFNMKPRLKSIFRRGLVKVAQTT 201
Query: 62 GAWIFTGGVNTGVIRHVGDALKDHASKS---RGKICTIGIAPWGIVENQEDLIGRDVVRP 118
GAWI TGG +TGV++ VG+A++D + S G++ TIG+A WG V +E LI P
Sbjct: 202 GAWIITGGSHTGVMKQVGEAVRDFSLSSSYKEGELITIGVATWGTVHRREGLIHPTGSFP 261
Query: 119 --YQTMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRCLPF 176
Y + LT L+S HSHFIL D+GT G+YG E+ LR +LEK IS Q
Sbjct: 262 AEYILDEDGQGNLTCLDSNHSHFILVDDGTHGQYGVEIPLRTRLEKFISEQT-------- 313
Query: 177 FSLDSRLFYSFWGSCQLDSVGIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDG 236
+ G+ +P+V +++EGGP + + T P VV +G
Sbjct: 314 ----------------KERGGVAIKIPIVCVVLEGGPGTLHTIDN--ATTNGTPCVVVEG 355
Query: 237 SGRASDILAFGHKYSEEGGLINESLRDQLLVTIQKTF-TYTRTQAQHLFIILMECMKKKE 295
SGR +D++A I+ ++ +L V Q+ F T+T ++ + + +++++
Sbjct: 356 SGRVADVIAQVANLPVSDITIS-LIQQKLSVFFQEMFETFTESRIVEWTKKIQDIVRRRQ 414
Query: 296 LITVFRMGSEGHQDIDLAILTALLKGANASA-------PDQLSLALAWNRVDIARSQIFI 348
L+TVFR G +G QD+D+AIL ALLK + + QL LA+AWNRVDIARS+IF+
Sbjct: 415 LLTVFREGKDGQQDVDVAILQALLKASRSQDHFGHENWDHQLKLAVAWNRVDIARSEIFM 474
Query: 349 YGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLY 408
QW L M AL+ ++ +FVKL +ENGV + F+T L LY + L+
Sbjct: 475 DEWQWKPSDLHPTMTAALISNKPEFVKLFLENGVQLKEFVTWDTLLYLYENLD--PSCLF 532
Query: 409 H------LVRDVKKGNLPPDY-RISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGP 461
H LV D ++ P R+ + + V+ L+G + Y R R L
Sbjct: 533 HSKLQKVLVEDPERPACAPAAPRLQMHHVAQVLRELLGDFTQPLYPRPRHNDRLRLLLPV 592
Query: 462 KRDDIPLRRG--RKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQ 519
+ ++ R K+ V +D P +L++WA++ R+++A W
Sbjct: 593 PHVKLNVQGVSLRSLYKRSSGHVTFTMD---------PIRDLLIWAIVQNRRELAGIIWA 643
Query: 520 HGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQ 579
++ +A AL K+ K ++ E + D S+E+ + ++ A+ + + Y++DE+
Sbjct: 644 QSQDCIAAALACSKILKELSKEEEDTDS----SEEMLALAEEYEHRAIGVFTECYRKDEE 699
Query: 580 LAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGL-KVI 638
A KLLT + W TCLQLA+ AK F++H Q LT +W G+L + ++GL +V
Sbjct: 700 RAQKLLTRVSEAWGKTTCLQLALEAKDMKFVSHGGIQAFLTKVWWGQLSV--DNGLWRVT 757
Query: 639 LGILLPPSILSLEFKNKDDMPYMSQAQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRN 698
L +L P + LT ++
Sbjct: 758 LCMLAFPLL-------------------------------------------LTGLI--- 771
Query: 699 NGESSRKKDEEEVQSKHRLIPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKME 758
S R+K ++V + + F+ AP+V F L+Y +L LF Y+++V +
Sbjct: 772 ---SFREKRLQDVGTP------AARARAFFTAPVVVFHLNILSYFAFLCLFAYVLMVDFQ 822
Query: 759 RWPSTQEWIVISYIFTLGIEKMREILMSEPGK--LLQKVKVWLQEYWNVTDLIAILLFSV 816
PS E + ++F+L E+MR+ L +P + L++K ++ ++WN D+ AILLF
Sbjct: 823 PVPSWCECAIYLWLFSLVCEEMRQ-LFYDPDECGLMKKAALYFSDFWNKLDVGAILLFVA 881
Query: 817 GMILRLQDQPFRSDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVII 876
G+ RL GRVI ++ I + +RL+ IF ++K LGP ++++ +MM D+ +F+ +
Sbjct: 882 GLTCRLIPATLYP-GRVILSLDFILFCLRLMHIFTISKTLGPKIIIVKRMMKDVFFFLFL 940
Query: 877 MLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYGEV--FADQID---PPCGQNE 931
+ V ++SFGVA+QAIL NE L + Y Y I+G++ + D ++ C N
Sbjct: 941 LAVWVVSFGVAKQAILIHNERRVDWLFRGAVYHSYLTIFGQIPGYIDGVNFNPEHCSPNG 1000
Query: 932 TR-------EDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSI 984
T E Q P W+ ++ YLL NILL+NLLIA+FN TF +V+
Sbjct: 1001 TDPYKPKCPESDATQQRPAFPE--WLTVLLLCLYLLFTNILLLNLLIAMFNYTFQQVQEH 1058
Query: 985 SNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLF 1044
++Q+WKFQR+ LI +H RP PPP I+ SH+ + + + + P +R LK
Sbjct: 1059 TDQIWKFQRHDLIEEYHGRPAAPPPFILLSHLQLFIKRVVLK------TPAKRHKQLKNK 1112
Query: 1045 ITDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVTSERVENMSMRLE-EVNEREHS 1103
+ +E + +E E Y + + + +++I S +V+ M L+ + +R S
Sbjct: 1113 LEKNEEAALLSWEIYLKENYLQNRQFQQKQRPEQKIEDISNKVDAMVDLLDLDPLKRSGS 1172
Query: 1104 MKASLQTVDIRLAQLEDLIGRMATALERLTGLERA 1138
M+ RLA LE+ + + A AL + RA
Sbjct: 1173 MEQ-------RLASLEEQVAQTARALHWIVRTLRA 1200
>gi|55953096 transient receptor potential cation channel, subfamily
M, member 3 isoform c [Homo sapiens]
Length = 255
Score = 518 bits (1335), Expect = e-146
Identities = 255/255 (100%), Positives = 255/255 (100%)
Query: 1 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 60
MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT
Sbjct: 1 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 60
Query: 61 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 120
TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ
Sbjct: 61 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 120
Query: 121 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRCLPFFSLD 180
TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRCLPFFSLD
Sbjct: 121 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRCLPFFSLD 180
Query: 181 SRLFYSFWGSCQLDSVGIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRA 240
SRLFYSFWGSCQLDSVGIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRA
Sbjct: 181 SRLFYSFWGSCQLDSVGIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRA 240
Query: 241 SDILAFGHKYSEEGG 255
SDILAFGHKYSEEGG
Sbjct: 241 SDILAFGHKYSEEGG 255
>gi|21314671 transient receptor potential cation channel, subfamily M,
member 4 [Homo sapiens]
Length = 1214
Score = 467 bits (1202), Expect = e-131
Identities = 347/1178 (29%), Positives = 587/1178 (49%), Gaps = 120/1178 (10%)
Query: 2 YVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTT 61
++R+S T P + L+T+ W P L++SV GG LQ L+ + +GL++AA +T
Sbjct: 90 FLRLSDRTDPAAVYSLVTRTWGFRAPNLVVSVLGGSGGPVLQTWLQDLLRRGLVRAAQST 149
Query: 62 GAWIFTGGVNTGVIRHVGDALKDHASKSRG--KICTIGIAPWGIVENQEDLIGRDVVRP- 118
GAWI TGG++TG+ RHVG A++DH S G K+ +G+APWG+V N++ LI P
Sbjct: 150 GAWIVTGGLHTGIGRHVGVAVRDHQMASTGGTKVVAMGVAPWGVVRNRDTLINPKGSFPA 209
Query: 119 -YQTMSNPMSKLTV-LNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRCLPF 176
Y+ +P + L+ +S F L D+GT G G E + R +LE +IS QK
Sbjct: 210 RYRWRGDPEDGVQFPLDYNYSAFFLVDDGTHGCLGGENRFRLRLESYISQQKTGVG---- 265
Query: 177 FSLDSRLFYSFWGSCQLDSVGIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDG 236
G G +PV+ L+++G +++ + + +P ++ G
Sbjct: 266 --------------------GTGIDIPVLLLLIDGDEKMLTRIENATQ--AQLPCLLVAG 303
Query: 237 SGRASDILAFGHKYS---EEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKK 293
SG A+D LA + + GG RD++ + F + + + L + M +
Sbjct: 304 SGGAADCLAETLEDTLAPGSGGARQGEARDRI-----RRF-FPKGDLEVLQAQVERIMTR 357
Query: 294 KELITVFRMGSEGHQDIDLAILTALLKGANASAP----DQLSLALAWNRVDIARSQIFIY 349
KEL+TV+ +G ++ + +L AL+K +S D+L LA+AWNRVDIA+S++F
Sbjct: 358 KELLTVYS-SEDGSEEFETIVLKALVKACGSSEASAYLDELRLAVAWNRVDIAQSELFRG 416
Query: 350 GQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYH 409
QW LE +++DAL+ DR +FV+LLI +G+S+ FLT RL +LY+ PSN+L
Sbjct: 417 DIQWRSFHLEASLMDALLNDRPEFVRLLISHGLSLGHFLTPMRLAQLYSA--APSNSLIR 474
Query: 410 LVRDVKK---GNLPPDYR-----ISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGP 461
+ D G P + + D+G V+ L+G Y G
Sbjct: 475 NLLDQASHSAGTKAPALKGGAAELRPPDVGHVLRMLLGKMCAPRYPS-----------GG 523
Query: 462 KRDDIPLRRGRKTTKKREEEVDIDLD-DPEINHFPFPFHELMVWAVLMKRQKMALFFWQH 520
D P + ++ ++ L D + P+ +L++WA+L+ R +MA++FW+
Sbjct: 524 AWDPHPGQGFGESMYLLSDKATSPLSLDAGLGQAPWS--DLLLWALLLNRAQMAMYFWEM 581
Query: 521 GEEAMAKALVACKLCKAMAH---EASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQD 577
G A++ AL AC L + MA +A E D++ + F + V+L + Y+
Sbjct: 582 GSNAVSSALGACLLLRVMARLEPDAEEAARRKDLAFK-------FEGMGVDLFGECYRSS 634
Query: 578 EQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKV 637
E A +LL W +ATCLQLA+ A R F A Q LLT W G + +
Sbjct: 635 EVRAARLLLRRCPLWGDATCLQLAMQADARAFFAQDGVQSLLTQKWWGDMASTTPIWA-L 693
Query: 638 ILGILLPPSILS--LEFKNKDDMPYMSQAQEIHLQEKEAEEPEKPTKEKEEEDMELTAML 695
+L PP I + + F+ ++ P + + E P E+ + +
Sbjct: 694 VLAFFCPPLIYTRLITFRKSEEEPTREELEFDMDSVINGEGPVGTADPAEKTPLGVPRQS 753
Query: 696 GRNNGESSRKKDEEEVQSKHRLIPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLV 755
GR R + R+ + F+ AP+ F ++Y+ +L+LF+ ++LV
Sbjct: 754 GRPGCCGGRCGGRRCL----------RRWFHFWGAPVTIFMGNVVSYLLFLLLFSRVLLV 803
Query: 756 KMERWP-STQEWIVISYIFTLGIEKMREILMSEPGKLL------------QKVKVWLQEY 802
+ P + E ++ + FTL E++R+ L G L Q+++++L +
Sbjct: 804 DFQPAPPGSLELLLYFWAFTLLCEELRQGLSGGGGSLASGGPGPGHASLSQRLRLYLADS 863
Query: 803 WNVTDLIAILLFSVGMILRLQDQPFRSDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMM 862
WN DL+A+ F +G+ RL + GR + C++ + + +RLL IF VNK LGP +++
Sbjct: 864 WNQCDLVALTCFLLGVGCRLTPGLYHL-GRTVLCIDFMVFTVRLLHIFTVNKQLGPKIVI 922
Query: 863 IGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQ 922
+ KMM D+ +F+ + V L+++GVA + +L P + + + +FY PY I+G++ +
Sbjct: 923 VSKMMKDVFFFLFFLGVWLVAYGVATEGLLRPRDSDFPSILRRVFYRPYLQIFGQIPQED 982
Query: 923 IDPPCGQ--NETREDGKIIQLPPCKTGA-------WIVPAIMACYLLVANILLVNLLIAV 973
+D + N + E G P + G W+V ++ +LLVANILLVNLLIA+
Sbjct: 983 MDVALMEHSNCSSEPGFWAHPPGAQAGTCVSQYANWLVVLLLVIFLLVANILLVNLLIAM 1042
Query: 974 FNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHLCCRWRKHESD 1033
F+ TF +V+ S+ WK QRY+LI FH RP L PP I+ SH+ ++ + LC R R +
Sbjct: 1043 FSYTFGKVQGNSDLYWKAQRYRLIREFHSRPALAPPFIVISHLRLLLRQLCRRPRSPQPS 1102
Query: 1034 PDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVTSERVENMSMR 1093
++ +++++ + +K+ +E E + + S+ ER++ TS++V+ +
Sbjct: 1103 SPALEH-FRVYLSKEAERKLLTWESVHKENFLLARARDKRESDSERLKRTSQKVDLALKQ 1161
Query: 1094 LEEVNEREHSMKASLQTVDIRLAQLEDLIGRMATALER 1131
L + E E +K ++ + Q ++G +A AL R
Sbjct: 1162 LGHIREYEQRLK----VLEREVQQCSRVLGWVAEALSR 1195
>gi|11225266 transient receptor potential cation channel, subfamily M,
member 5 [Homo sapiens]
Length = 1165
Score = 460 bits (1184), Expect = e-129
Identities = 344/1157 (29%), Positives = 567/1157 (49%), Gaps = 146/1157 (12%)
Query: 2 YVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTT 61
+VRV P +L L+ EW L P L++S+ G Q F ++ L+ V KGL+KAA +T
Sbjct: 40 FVRVPSGVAPSVLFDLLLAEWHLPAPNLVVSLVGEEQPFAMKSWLRDVLRKGLVKAAQST 99
Query: 62 GAWIFTGGVNTGVIRHVGDALKDHA---SKSRGKICTIGIAPWGIV-------ENQEDLI 111
GAWI T + G+ RHVG A++DH+ + ++ ++ +G+A G V E QED
Sbjct: 100 GAWILTSALRVGLARHVGQAVRDHSLASTSTKVRVVAVGMASLGRVLHRRILEEAQEDF- 158
Query: 112 GRDVVRPYQTMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINT 171
V + L L+S SHFIL + G GK +LR +LEKHIS Q+
Sbjct: 159 ---PVHYPEDDGGSQGPLCSLDSNLSHFILVEPGPPGKGDGLTELRLRLEKHISEQRAG- 214
Query: 172 RCLPFFSLDSRLFYSFWGSCQLDSVGIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPV 231
Y GS + +PV+ L+V G PN + + + P +
Sbjct: 215 -------------YGGTGSIE---------IPVLCLLVNGDPNTLERISRAVEQAAPWLI 252
Query: 232 VVCDGSGRASDILAFGHKYSEEGGLINESLRDQLLV--TIQKTFTYTRTQAQHLFI---- 285
+V GSG +D+LA L+N+ LLV +K F + ++H
Sbjct: 253 LV--GSGGIADVLA---------ALVNQP---HLLVPKVAEKQFK-EKFPSKHFSWEDIV 297
Query: 286 ----ILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANASAP------DQLSLALA 335
+L + L+TV+ EG +++D IL AL+K + + D+L LA+A
Sbjct: 298 RWTKLLQNITSHQHLLTVYDFEQEGSEELDTVILKALVKACKSHSQEPQDYLDELKLAVA 357
Query: 336 WNRVDIARSQIFIYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEE 395
W+RVDIA+S+IF +W LE+ M+DALV ++ +FV+L ++NG + FLT RL+E
Sbjct: 358 WDRVDIAKSEIFNGDVEWKSCDLEEVMVDALVSNKPEFVRLFVDNGADVADFLTYGRLQE 417
Query: 396 LYNTRHGPSNTLYHLVRDVKKGNL----------------PPDYRISLIDIGLVIEYLMG 439
LY + S L R ++ L PP + SL ++ V++ +
Sbjct: 418 LYRSVSRKSLLFDLLQRKQEEARLTLAGLGTQQAREPPAGPPAF--SLHEVSRVLKDFLQ 475
Query: 440 GAYRCNYTRKRFRTLYHNLFGPKRDDIP--LRRGRKTTKKRE--EEVDIDLDDPEINHFP 495
A R Y +D P RR K KR ++ +DL+ N
Sbjct: 476 DACRGFY----------------QDGRPGDRRRAEKGPAKRPTGQKWLLDLNQKSEN--- 516
Query: 496 FPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQEL 555
P+ +L +WAVL R +MA +FW G+E +A AL ACK+ K M+H +E + +
Sbjct: 517 -PWRDLFLWAVLQNRHEMATYFWAMGQEGVAAALAACKILKEMSHLETEAEAARATREA- 574
Query: 556 NHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCS 615
+ +LA++L + Y E A LL + WS TCL LA A + F AH
Sbjct: 575 -----KYERLALDLFSECYSNSEARAFALLVRRNRCWSKTTCLHLATEADAKAFFAHDGV 629
Query: 616 QMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKN-KDDMPYMSQAQEIHLQEKEA 674
Q LT +W G M + + +LG L P+++ ++ P + ++ LQ+ ++
Sbjct: 630 QAFLTRIWWGD--MAAGTPILRLLGAFLCPALVYTNLITFSEEAPLRTGLED--LQDLDS 685
Query: 675 EEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPLGRKIYEFYNAPIVK 734
+ EK + +E R G+ R + L + +F+ AP+
Sbjct: 686 LDTEKSPLYGLQSRVEELVEAPRAQGDRGP-----------RAVFLLTRWRKFWGAPVTV 734
Query: 735 FWFYTLAYIGYLMLFNYIVLVKME---RWPSTQEWIVISYIFTLGIEKMRE-ILMSEPGK 790
F + Y +L LF Y++LV + PS E + ++FTL +E++R+ E
Sbjct: 735 FLGNVVMYFAFLFLFTYVLLVDFRPPPQGPSGPEVTLYFWVFTLVLEEIRQGFFTDEDTH 794
Query: 791 LLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSDGRVIYCVNIIYWYIRLLDIF 850
L++K +++ + WN D++AI LF VG+ R+ F + GR + ++ + + +RL+ IF
Sbjct: 795 LVKKFTLYVGDNWNKCDMVAIFLFIVGVTCRMLPSAFEA-GRTVLAMDFMVFTLRLIHIF 853
Query: 851 GVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMP 910
++K LGP ++++ +MM D+ +F+ + V L+++GV QA+L P++ + + + Y P
Sbjct: 854 AIHKQLGPKIIVVERMMKDVFFFLFFLSVWLVAYGVTTQALLHPHDGRLEWIFRRVLYRP 913
Query: 911 YWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKT--GAWIVPAIMACYLLVANILLVN 968
Y I+G++ D+ID N + + P C + W+V ++ +LLV N+LL+N
Sbjct: 914 YLQIFGQIPLDEIDE-ARVNCSTHPLLLEDSPSCPSLYANWLVILLLVTFLLVTNVLLMN 972
Query: 969 LLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTMIFQHLCCRWR 1028
LLIA+F+ TF V+ ++ WKFQRY LI+ +HERP L PP I+ SH+++ + + +
Sbjct: 973 LLIAMFSYTFQVVQGNADMFWKFQRYNLIVEYHERPALAPPFILLSHLSLTLRRVFKKEA 1032
Query: 1029 KHESDPDERDYGLKLFITDDELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRVTSERVE 1088
+H+ + ERD + D +KV +E E + + + R S E +R T+ RV+
Sbjct: 1033 EHKREHLERD------LPDPLDQKVVTWETVQKENFLSKMEKRRRDSEGEVLRKTAHRVD 1086
Query: 1089 NMSMRLEEVNEREHSMK 1105
++ L + E+E +K
Sbjct: 1087 FIAKYLGGLREQEKRIK 1103
>gi|45935368 transient receptor potential cation channel, subfamily
M, member 3 isoform h [Homo sapiens]
Length = 230
Score = 450 bits (1158), Expect = e-126
Identities = 230/255 (90%), Positives = 230/255 (90%), Gaps = 25/255 (9%)
Query: 1 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 60
MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT
Sbjct: 1 MYVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMT 60
Query: 61 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 120
TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ
Sbjct: 61 TGAWIFTGGVNTGVIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQ 120
Query: 121 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRCLPFFSLD 180
TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTR
Sbjct: 121 TMSNPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTR-------- 172
Query: 181 SRLFYSFWGSCQLDSVGIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRA 240
IGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRA
Sbjct: 173 -----------------IGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRA 215
Query: 241 SDILAFGHKYSEEGG 255
SDILAFGHKYSEEGG
Sbjct: 216 SDILAFGHKYSEEGG 230
>gi|109689695 transient receptor potential cation channel, subfamily
M, member 8 [Homo sapiens]
Length = 1104
Score = 276 bits (705), Expect = 1e-73
Identities = 196/662 (29%), Positives = 322/662 (48%), Gaps = 89/662 (13%)
Query: 2 YVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTT 61
Y+R+S DT ++L L+T+ W L+ P L+ISV GG +NF L+P+++++F + LI A +
Sbjct: 117 YIRLSCDTDAEILYELLTQHWHLKTPNLVISVTGGAKNFALKPRMRKIFSR-LIYIAQSK 175
Query: 62 GAWIFTGGVNTGVIRHVGDALKDH--ASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPY 119
GAWI TGG + G+++++G+ ++D+ + S I IGIA WG+V N++ LI Y
Sbjct: 176 GAWILTGGTHYGLMKYIGEVVRDNTISRSSEENIVAIGIAAWGMVSNRDTLIRNCDAEGY 235
Query: 120 QTMSNPMSKLT-----VLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRCL 174
M T +L++ H+H +L DNG G E KLR QLEK+IS + I
Sbjct: 236 FLAQYLMDDFTRDPLYILDNNHTHLLLVDNGCHGHPTVEAKLRNQLEKYISERTIQ---- 291
Query: 175 PFFSLDSRLFYSFWGSCQLDSVGIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVC 234
DS G +P+V GG + + +++ +P VV
Sbjct: 292 -------------------DS-NYGGKIPIVCFAQGGGKETLKAINTSIKNK--IPCVVV 329
Query: 235 DGSGRASDILAFGHKYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQHLFII-LMECMKK 293
+GSG+ +D++A E L + +++++L+ + +T + + +I L E ++
Sbjct: 330 EGSGQIADVIA--SLVEVEDALTSSAVKEKLVRFLPRTVSRLPEEETESWIKWLKEILEC 387
Query: 294 KELITVFRMGSEGHQDIDLAILTALLKGANASAPD------QLSLALAWNRVDIARSQIF 347
L+TV +M G + + AI AL K + S D QL L L WN++D+A +IF
Sbjct: 388 SHLLTVIKMEEAGDEIVSNAISYALYKAFSTSEQDKDNWNGQLKLLLEWNQLDLANDEIF 447
Query: 348 IYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTL 407
++W L++ M AL+ DR FV+L +ENG+++ +FLT L EL++ S +
Sbjct: 448 TNDRRWESADLQEVMFTALIKDRPKFVRLFLENGLNLRKFLTHDVLTELFSNHF--STLV 505
Query: 408 YHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRDDIP 467
Y ++ K S D L + + +R
Sbjct: 506 YRNLQIAKN---------SYNDALLTFVWKLVANFR------------------------ 532
Query: 468 LRRGRKTTKKREEEVDIDLDD--PEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAM 525
R RK + +E+DI+L D P H P L +WA+L +++++ W+
Sbjct: 533 -RGFRKEDRNGRDEMDIELHDVSPITRH---PLQALFIWAILQNKKELSKVIWEQTRGCT 588
Query: 526 AKALVACKLCKAMAHEASENDMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLL 585
AL A KL K +A ++ + + S+EL + ++ AVEL + Y DE LA +LL
Sbjct: 589 LAALGASKLLKTLAKVKNDINAAGE-SEEL---ANEYETRAVELFTECYSSDEDLAEQLL 644
Query: 586 TYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPP 645
Y + W + CL+LAV A + FIA Q L+ W G + R K+IL + + P
Sbjct: 645 VYSCEAWGGSNCLELAVEATDQHFIAQPGVQNFLSKQWYGEI-SRDTKNWKIILCLFIIP 703
Query: 646 SI 647
+
Sbjct: 704 LV 705
Score = 172 bits (435), Expect = 3e-42
Identities = 109/370 (29%), Positives = 193/370 (52%), Gaps = 32/370 (8%)
Query: 727 FYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIVISYIFTLGIEKMREILMS 786
F+ +P V F + + YI +L+LF Y++L+ P E ++ S +F L +++R+ ++
Sbjct: 730 FFTSPFVVFSWNVVFYIAFLLLFAYVLLMDFHSVPHPPELVLYSLVFVLFCDEVRQWYVN 789
Query: 787 EPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRS--DGRVIYCVNIIYWYI 844
+ + WNV D + + F G++ RL S GRVI+C++ I + +
Sbjct: 790 GVN--------YFTDLWNVMDTLGLFYFIAGIVFRLHSSNKSSLYSGRVIFCLDYIIFTL 841
Query: 845 RLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAK 904
RL+ IF V++ LGP ++M+ +M+ID+ +F+ + V +++FGVARQ IL NE+ + +
Sbjct: 842 RLIHIFTVSRNLGPKIIMLQRMLIDVFFFLFLFAVWMVAFGVARQGILRQNEQRWRWIFR 901
Query: 905 NIFYMPYWMIYGEVFADQID------PPCGQNETREDGKIIQLPP---CKTGAWIVPAIM 955
++ Y PY ++G+V +D +D C ++L + WI ++
Sbjct: 902 SVIYEPYLAMFGQVPSD-VDGTTYDFAHCTFTGNESKPLCVELDEHNLPRFPEWITIPLV 960
Query: 956 ACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLPPPLIIFSH 1015
Y+L NILLVNLL+A+F T V+ ++QVWKFQRY L+ + R +P P I+F++
Sbjct: 961 CIYMLSTNILLVNLLVAMFGYTVGTVQENNDQVWKFQRYFLVQEYCSRLNIPFPFIVFAY 1020
Query: 1016 MTMIFQ---HLCCRWRKHES------DPDERDYGLKLFITDDELKKVHDFEEQCIEEY-- 1064
M+ + CC+ + ES + D + + ++ L K++ EE
Sbjct: 1021 FYMVVKKCFKCCCKEKNMESSVCCFKNEDNETLAWEGVMKENYLVKINTKANDTSEEMRH 1080
Query: 1065 -FREKDDRFN 1073
FR+ D + N
Sbjct: 1081 RFRQLDTKLN 1090
>gi|209863032 transient receptor potential cation channel, subfamily
C, member 4 isoform zeta [Homo sapiens]
Length = 804
Score = 80.5 bits (197), Expect = 1e-14
Identities = 76/377 (20%), Positives = 164/377 (43%), Gaps = 71/377 (18%)
Query: 727 FYNAPIVKFWFYTLAYIGYLMLF----NYIVLVKMERW---PSTQEWIVISYIFTLGIEK 779
F P +KF +T +Y+ +L L +I + R P+ EW+++ ++ +
Sbjct: 185 FIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWGE 244
Query: 780 MREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQD-------QPFRS--- 829
+++ M + G ++ ++ ++WN+ D + L+ + L++ P S
Sbjct: 245 IKQ--MWDGG-----LQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDM 297
Query: 830 -----DGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSF 884
++ + I+ +RL+ +F N +LGP + +G+M++D++ F+ I +VL++F
Sbjct: 298 WHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAF 357
Query: 885 GVARQAILFPNEEPSWKLAKNI---------------FYMPYWMIYGEVFADQIDPPCGQ 929
+ F EE K I +W I+G + + Q
Sbjct: 358 ANGLNQLYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINL-YVTNVKAQ 416
Query: 930 NETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVW 989
+E E ++ + Y +++ ++L+N+LIA+ NN++ + ++ W
Sbjct: 417 HEFTE--------------FVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEW 462
Query: 990 KFQRYQLIMTFHER--------PVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGL 1041
KF R +L M++ E V+P P ++ + I+ HLC + + + + +G
Sbjct: 463 KFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTHLCKKKMRRKPE----SFGT 518
Query: 1042 KLFITDDELKKVHDFEE 1058
D L++ H ++E
Sbjct: 519 IGRRAADNLRRHHQYQE 535
>gi|209863030 transient receptor potential cation channel, subfamily
C, member 4 isoform delta [Homo sapiens]
Length = 836
Score = 80.5 bits (197), Expect = 1e-14
Identities = 76/377 (20%), Positives = 164/377 (43%), Gaps = 71/377 (18%)
Query: 727 FYNAPIVKFWFYTLAYIGYLMLF----NYIVLVKMERW---PSTQEWIVISYIFTLGIEK 779
F P +KF +T +Y+ +L L +I + R P+ EW+++ ++ +
Sbjct: 358 FIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWGE 417
Query: 780 MREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQD-------QPFRS--- 829
+++ M + G ++ ++ ++WN+ D + L+ + L++ P S
Sbjct: 418 IKQ--MWDGG-----LQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDM 470
Query: 830 -----DGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSF 884
++ + I+ +RL+ +F N +LGP + +G+M++D++ F+ I +VL++F
Sbjct: 471 WHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAF 530
Query: 885 GVARQAILFPNEEPSWKLAKNI---------------FYMPYWMIYGEVFADQIDPPCGQ 929
+ F EE K I +W I+G + + Q
Sbjct: 531 ANGLNQLYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINL-YVTNVKAQ 589
Query: 930 NETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVW 989
+E E ++ + Y +++ ++L+N+LIA+ NN++ + ++ W
Sbjct: 590 HEFTE--------------FVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEW 635
Query: 990 KFQRYQLIMTFHER--------PVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGL 1041
KF R +L M++ E V+P P ++ + I+ HLC + + + + +G
Sbjct: 636 KFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTHLCKKKMRRKPE----SFGT 691
Query: 1042 KLFITDDELKKVHDFEE 1058
D L++ H ++E
Sbjct: 692 IGRRAADNLRRHHQYQE 708
Score = 32.0 bits (71), Expect = 4.8
Identities = 28/109 (25%), Positives = 52/109 (47%), Gaps = 15/109 (13%)
Query: 549 DDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTY-------ELKNWSNATCLQLA 601
++ E SR Q A +LLDQ+ + +L + +L Y E ++ ++ L+LA
Sbjct: 235 NEFKSEYEELSRQCKQFAKDLLDQT-RSSRELEI-ILNYRDDNSLIEEQSGNDLARLKLA 292
Query: 602 VAAKHRDFIAHTCSQMLLTDMWMGRLR--MRKNSGLKV----ILGILLP 644
+ + ++F+A Q LL W R++ +K+ I+G+L P
Sbjct: 293 IKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFP 341
>gi|209863026 transient receptor potential cation channel, subfamily
C, member 4 isoform beta [Homo sapiens]
Length = 893
Score = 80.5 bits (197), Expect = 1e-14
Identities = 76/377 (20%), Positives = 164/377 (43%), Gaps = 71/377 (18%)
Query: 727 FYNAPIVKFWFYTLAYIGYLMLF----NYIVLVKMERW---PSTQEWIVISYIFTLGIEK 779
F P +KF +T +Y+ +L L +I + R P+ EW+++ ++ +
Sbjct: 358 FIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWGE 417
Query: 780 MREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQD-------QPFRS--- 829
+++ M + G ++ ++ ++WN+ D + L+ + L++ P S
Sbjct: 418 IKQ--MWDGG-----LQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDM 470
Query: 830 -----DGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSF 884
++ + I+ +RL+ +F N +LGP + +G+M++D++ F+ I +VL++F
Sbjct: 471 WHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAF 530
Query: 885 GVARQAILFPNEEPSWKLAKNI---------------FYMPYWMIYGEVFADQIDPPCGQ 929
+ F EE K I +W I+G + + Q
Sbjct: 531 ANGLNQLYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINL-YVTNVKAQ 589
Query: 930 NETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVW 989
+E E ++ + Y +++ ++L+N+LIA+ NN++ + ++ W
Sbjct: 590 HEFTE--------------FVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEW 635
Query: 990 KFQRYQLIMTFHER--------PVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGL 1041
KF R +L M++ E V+P P ++ + I+ HLC + + + + +G
Sbjct: 636 KFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTHLCKKKMRRKPE----SFGT 691
Query: 1042 KLFITDDELKKVHDFEE 1058
D L++ H ++E
Sbjct: 692 IGRRAADNLRRHHQYQE 708
Score = 32.0 bits (71), Expect = 4.8
Identities = 28/109 (25%), Positives = 52/109 (47%), Gaps = 15/109 (13%)
Query: 549 DDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTY-------ELKNWSNATCLQLA 601
++ E SR Q A +LLDQ+ + +L + +L Y E ++ ++ L+LA
Sbjct: 235 NEFKSEYEELSRQCKQFAKDLLDQT-RSSRELEI-ILNYRDDNSLIEEQSGNDLARLKLA 292
Query: 602 VAAKHRDFIAHTCSQMLLTDMWMGRLR--MRKNSGLKV----ILGILLP 644
+ + ++F+A Q LL W R++ +K+ I+G+L P
Sbjct: 293 IKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFP 341
>gi|7706747 transient receptor potential cation channel, subfamily C,
member 4 isoform alpha [Homo sapiens]
Length = 977
Score = 80.5 bits (197), Expect = 1e-14
Identities = 76/377 (20%), Positives = 164/377 (43%), Gaps = 71/377 (18%)
Query: 727 FYNAPIVKFWFYTLAYIGYLMLF----NYIVLVKMERW---PSTQEWIVISYIFTLGIEK 779
F P +KF +T +Y+ +L L +I + R P+ EW+++ ++ +
Sbjct: 358 FIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWGE 417
Query: 780 MREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQD-------QPFRS--- 829
+++ M + G ++ ++ ++WN+ D + L+ + L++ P S
Sbjct: 418 IKQ--MWDGG-----LQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDM 470
Query: 830 -----DGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSF 884
++ + I+ +RL+ +F N +LGP + +G+M++D++ F+ I +VL++F
Sbjct: 471 WHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAF 530
Query: 885 GVARQAILFPNEEPSWKLAKNI---------------FYMPYWMIYGEVFADQIDPPCGQ 929
+ F EE K I +W I+G + + Q
Sbjct: 531 ANGLNQLYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINL-YVTNVKAQ 589
Query: 930 NETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVW 989
+E E ++ + Y +++ ++L+N+LIA+ NN++ + ++ W
Sbjct: 590 HEFTE--------------FVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEW 635
Query: 990 KFQRYQLIMTFHER--------PVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGL 1041
KF R +L M++ E V+P P ++ + I+ HLC + + + + +G
Sbjct: 636 KFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTHLCKKKMRRKPE----SFGT 691
Query: 1042 KLFITDDELKKVHDFEE 1058
D L++ H ++E
Sbjct: 692 IGRRAADNLRRHHQYQE 708
Score = 32.0 bits (71), Expect = 4.8
Identities = 28/109 (25%), Positives = 52/109 (47%), Gaps = 15/109 (13%)
Query: 549 DDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTY-------ELKNWSNATCLQLA 601
++ E SR Q A +LLDQ+ + +L + +L Y E ++ ++ L+LA
Sbjct: 235 NEFKSEYEELSRQCKQFAKDLLDQT-RSSRELEI-ILNYRDDNSLIEEQSGNDLARLKLA 292
Query: 602 VAAKHRDFIAHTCSQMLLTDMWMGRLR--MRKNSGLKV----ILGILLP 644
+ + ++F+A Q LL W R++ +K+ I+G+L P
Sbjct: 293 IKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFP 341
>gi|209863024 transient receptor potential cation channel, subfamily
C, member 4 isoform epsilon [Homo sapiens]
Length = 982
Score = 78.2 bits (191), Expect = 6e-14
Identities = 71/343 (20%), Positives = 150/343 (43%), Gaps = 67/343 (19%)
Query: 727 FYNAPIVKFWFYTLAYIGYLMLF----NYIVLVKMERW---PSTQEWIVISYIFTLGIEK 779
F P +KF +T +Y+ +L L +I + R P+ EW+++ ++ +
Sbjct: 358 FIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWGE 417
Query: 780 MREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQD-------QPFRS--- 829
+++ M + G ++ ++ ++WN+ D + L+ + L++ P S
Sbjct: 418 IKQ--MWDGG-----LQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDM 470
Query: 830 -----DGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSF 884
++ + I+ +RL+ +F N +LGP + +G+M++D++ F+ I +VL++F
Sbjct: 471 WHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAF 530
Query: 885 GVARQAILFPNEEPSWKLAKNI---------------FYMPYWMIYGEVFADQIDPPCGQ 929
+ F EE K I +W I+G + + Q
Sbjct: 531 ANGLNQLYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINL-YVTNVKAQ 589
Query: 930 NETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVW 989
+E E ++ + Y +++ ++L+N+LIA+ NN++ + ++ W
Sbjct: 590 HEFTE--------------FVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEW 635
Query: 990 KFQRYQLIMTFHER--------PVLPPPLIIFSHMTMIFQHLC 1024
KF R +L M++ E V+P P ++ + I+ HLC
Sbjct: 636 KFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTHLC 678
Score = 32.0 bits (71), Expect = 4.8
Identities = 28/109 (25%), Positives = 52/109 (47%), Gaps = 15/109 (13%)
Query: 549 DDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTY-------ELKNWSNATCLQLA 601
++ E SR Q A +LLDQ+ + +L + +L Y E ++ ++ L+LA
Sbjct: 235 NEFKSEYEELSRQCKQFAKDLLDQT-RSSRELEI-ILNYRDDNSLIEEQSGNDLARLKLA 292
Query: 602 VAAKHRDFIAHTCSQMLLTDMWMGRLR--MRKNSGLKV----ILGILLP 644
+ + ++F+A Q LL W R++ +K+ I+G+L P
Sbjct: 293 IKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFP 341
>gi|6912736 transient receptor potential cation channel, subfamily C,
member 5 [Homo sapiens]
Length = 973
Score = 71.2 bits (173), Expect = 7e-12
Identities = 76/360 (21%), Positives = 154/360 (42%), Gaps = 77/360 (21%)
Query: 727 FYNAPIVKFWFYTLAYIGYLMLF----NYIVLVKMERW---PSTQEWIVISYIFTLGIEK 779
F P +KF +T +Y+ +L + +IV + P+ EW+++ ++ +
Sbjct: 359 FIKKPFIKFICHTASYLTFLFMLLLASQHIVRTDLHVQGPPPTVVEWMILPWVLGFIWGE 418
Query: 780 MREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQDQPFRSDGR------- 832
++E M + G ++ ++WN+ D L+ + L++ + R
Sbjct: 419 IKE--MWDGG-----FTEYIHDWWNLMDFAMNSLYLATISLKIVAYVKYNGSRPREEWEM 471
Query: 833 --------VIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSF 884
++ ++ I +RL+ +F N +LGP + +G+M++D++ F+ I +VL++F
Sbjct: 472 WHPTLIAEALFAISNILSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAF 531
Query: 885 GVARQAILF---------PNEEPSWKLAK--NIF-------YMPYWMIYG--EVFADQID 924
+ F PN + K N F +W ++G ++ +
Sbjct: 532 ANGLNQLYFYYETRAIDEPNNCKGIRCEKQNNAFSTLFETLQSLFWSVFGLLNLYVTNVK 591
Query: 925 PPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSI 984
++E E ++ + Y +++ ++L+N+LIA+ NN++ +
Sbjct: 592 ---ARHEFTE--------------FVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADH 634
Query: 985 SNQVWKFQRYQLIMT-FHERPVLPPPLII------FSHMTMIFQHLCCRWRKHESDPDER 1037
++ WKF R +L M+ F E LPPP I F ++ F + C R DPD R
Sbjct: 635 ADIEWKFARTKLWMSYFDEGGTLPPPFNIIPSPKSFLYLGNWFNNTFCPKR----DPDGR 690
>gi|209863028 transient receptor potential cation channel, subfamily
C, member 4 isoform gamma [Homo sapiens]
Length = 828
Score = 62.4 bits (150), Expect = 3e-09
Identities = 60/310 (19%), Positives = 135/310 (43%), Gaps = 60/310 (19%)
Query: 727 FYNAPIVKFWFYTLAYIGYLMLF----NYIVLVKMERW---PSTQEWIVISYIFTLGIEK 779
F P +KF +T +Y+ +L L +I + R P+ EW+++ ++ +
Sbjct: 358 FIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWGE 417
Query: 780 MREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQD-------QPFRS--- 829
+++ M + G ++ ++ ++WN+ D + L+ + L++ P S
Sbjct: 418 IKQ--MWDGG-----LQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDM 470
Query: 830 -----DGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSF 884
++ + I+ +RL+ +F N +LGP + +G+M++D++ F+ I +VL++F
Sbjct: 471 WHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAF 530
Query: 885 GVARQAILFPNEEPSWKLAKNI---------------FYMPYWMIYGEVFADQIDPPCGQ 929
+ F EE K I +W I+G + + Q
Sbjct: 531 ANGLNQLYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINL-YVTNVKAQ 589
Query: 930 NETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTF-FEVKSISNQV 988
+E E ++ + Y +++ ++L+N+LIA+ NN++ + ++ +
Sbjct: 590 HEFTE--------------FVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIARRAADNL 635
Query: 989 WKFQRYQLIM 998
+ +YQ +M
Sbjct: 636 RRHHQYQEVM 645
Score = 32.0 bits (71), Expect = 4.8
Identities = 28/109 (25%), Positives = 52/109 (47%), Gaps = 15/109 (13%)
Query: 549 DDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTY-------ELKNWSNATCLQLA 601
++ E SR Q A +LLDQ+ + +L + +L Y E ++ ++ L+LA
Sbjct: 235 NEFKSEYEELSRQCKQFAKDLLDQT-RSSRELEI-ILNYRDDNSLIEEQSGNDLARLKLA 292
Query: 602 VAAKHRDFIAHTCSQMLLTDMWMGRLR--MRKNSGLKV----ILGILLP 644
+ + ++F+A Q LL W R++ +K+ I+G+L P
Sbjct: 293 IKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFP 341
>gi|9966865 transient receptor potential cation channel, subfamily C,
member 7 [Homo sapiens]
Length = 862
Score = 57.0 bits (136), Expect = 1e-07
Identities = 46/198 (23%), Positives = 95/198 (47%), Gaps = 28/198 (14%)
Query: 823 QDQPFRSDGRVI----YCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIML 878
+D+ + SD ++I Y + ++ + R+ I N+ GP + +G+ + D+ F++I +
Sbjct: 528 RDKWWPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVIFI 587
Query: 879 VVLMSFGVARQAILF----PNEEPSWKLAKNIFYMPYWMIYG--EVFADQIDPPCGQNET 932
+V ++F + + P++ + F +W I+G EV + +
Sbjct: 588 MVFVAFMIGMFNLYSYYRGAKYNPAFTTVEESFKTLFWSIFGLSEVISVVL--------- 638
Query: 933 REDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQ 992
+ D K I+ I + Y + ++L+N+LIA+ NN++ E++ ++ WKF
Sbjct: 639 KYDHKFIEN--------IGYVLYGVYNVTMVVVLLNMLIAMINNSYQEIEEDADVEWKFA 690
Query: 993 RYQLIMT-FHERPVLPPP 1009
R +L ++ F E LP P
Sbjct: 691 RAKLWLSYFDEGRTLPAP 708
>gi|194733735 transient receptor potential cation channel, subfamily
C, member 3 isoform a [Homo sapiens]
Length = 921
Score = 56.6 bits (135), Expect = 2e-07
Identities = 48/226 (21%), Positives = 102/226 (45%), Gaps = 25/226 (11%)
Query: 794 KVKVWLQEYWNVTDLIAILLF-SVGMILRLQDQPFRSDGRVI----YCVNIIYWYIRLLD 848
K + ++ Y +DL + L + +D+ SD ++I Y + ++ + R+
Sbjct: 569 KAQQYVDSYVQESDLSEVTLPPEIQYFTYARDKWLPSDPQIISEGLYAIAVVLSFSRIAY 628
Query: 849 IFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAI----LFPNEEPSWKLAK 904
I N+ GP + +G+ + D+ F+++ ++V +F + + L ++ +
Sbjct: 629 ILPANESFGPLQISLGRTVKDIFKFMVLFIMVFFAFMIGMFILYSYYLGAKVNAAFTTVE 688
Query: 905 NIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANI 964
F +W I+G + + D K I+ I + Y + +
Sbjct: 689 ESFKTLFWSIFGLSEVTSV-------VLKYDHKFIEN--------IGYVLYGIYNVTMVV 733
Query: 965 LLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMT-FHERPVLPPP 1009
+L+N+LIA+ N+++ E++ S+ WKF R +L ++ F + LPPP
Sbjct: 734 VLLNMLIAMINSSYQEIEDDSDVEWKFARSKLWLSYFDDGKTLPPP 779
Score = 32.7 bits (73), Expect = 2.8
Identities = 19/103 (18%), Positives = 48/103 (46%), Gaps = 1/103 (0%)
Query: 718 IPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKME-RWPSTQEWIVISYIFTLG 776
I LGR + + + ++ + IG +L++Y + K+ + + +E + G
Sbjct: 641 ISLGRTVKDIFKFMVLFIMVFFAFMIGMFILYSYYLGAKVNAAFTTVEESFKTLFWSIFG 700
Query: 777 IEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMI 819
+ ++ +++ K ++ + L +NVT ++ +L + MI
Sbjct: 701 LSEVTSVVLKYDHKFIENIGYVLYGIYNVTMVVVLLNMLIAMI 743
>gi|4507687 transient receptor potential cation channel, subfamily C,
member 3 isoform b [Homo sapiens]
Length = 848
Score = 56.6 bits (135), Expect = 2e-07
Identities = 48/226 (21%), Positives = 102/226 (45%), Gaps = 25/226 (11%)
Query: 794 KVKVWLQEYWNVTDLIAILLF-SVGMILRLQDQPFRSDGRVI----YCVNIIYWYIRLLD 848
K + ++ Y +DL + L + +D+ SD ++I Y + ++ + R+
Sbjct: 496 KAQQYVDSYVQESDLSEVTLPPEIQYFTYARDKWLPSDPQIISEGLYAIAVVLSFSRIAY 555
Query: 849 IFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAI----LFPNEEPSWKLAK 904
I N+ GP + +G+ + D+ F+++ ++V +F + + L ++ +
Sbjct: 556 ILPANESFGPLQISLGRTVKDIFKFMVLFIMVFFAFMIGMFILYSYYLGAKVNAAFTTVE 615
Query: 905 NIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANI 964
F +W I+G + + D K I+ I + Y + +
Sbjct: 616 ESFKTLFWSIFGLSEVTSV-------VLKYDHKFIEN--------IGYVLYGIYNVTMVV 660
Query: 965 LLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMT-FHERPVLPPP 1009
+L+N+LIA+ N+++ E++ S+ WKF R +L ++ F + LPPP
Sbjct: 661 VLLNMLIAMINSSYQEIEDDSDVEWKFARSKLWLSYFDDGKTLPPP 706
Score = 32.7 bits (73), Expect = 2.8
Identities = 19/103 (18%), Positives = 48/103 (46%), Gaps = 1/103 (0%)
Query: 718 IPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKME-RWPSTQEWIVISYIFTLG 776
I LGR + + + ++ + IG +L++Y + K+ + + +E + G
Sbjct: 568 ISLGRTVKDIFKFMVLFIMVFFAFMIGMFILYSYYLGAKVNAAFTTVEESFKTLFWSIFG 627
Query: 777 IEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMI 819
+ ++ +++ K ++ + L +NVT ++ +L + MI
Sbjct: 628 LSEVTSVVLKYDHKFIENIGYVLYGIYNVTMVVVLLNMLIAMI 670
>gi|5730102 transient receptor potential cation channel, subfamily C,
member 6 [Homo sapiens]
Length = 931
Score = 54.3 bits (129), Expect = 9e-07
Identities = 70/349 (20%), Positives = 133/349 (38%), Gaps = 89/349 (25%)
Query: 762 STQEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILR 821
S E ++IS++ + + +EI P K +L E WN+ D + +F+ I R
Sbjct: 492 SWMEMLIISWVIGMIWAECKEIWTQGP-------KEYLFELWNMLDFGMLAIFAASFIAR 544
Query: 822 LQ-------------------------------------------DQPFRSDGRVIYCVN 838
D S+G +Y +
Sbjct: 545 FMAFWHASKAQSIIDANDTLKDLTKVTLGDNVKYYNLARIKWDPSDPQIISEG--LYAIA 602
Query: 839 IIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGV-----------A 887
++ + R+ I N+ GP + +G+ + D+ F++I ++V ++F + A
Sbjct: 603 VVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYIGA 662
Query: 888 RQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQNETREDGKIIQLPPCKTG 947
+Q F E S+K +W I+G + G ++
Sbjct: 663 KQNEAFTTVEESFKTL-------FWAIFGLSEVKSVVINYNHKFIENIGYVLY------- 708
Query: 948 AWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMT-FHERPVL 1006
Y + I+L+N+LIA+ N++F E++ ++ WKF R +L + F E L
Sbjct: 709 --------GVYNVTMVIVLLNMLIAMINSSFQEIEDDADVEWKFARAKLWFSYFEEGRTL 760
Query: 1007 PPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGLKLFITDDELKKVHD 1055
P P + +F +L + +K S+ + K F D E+ K+++
Sbjct: 761 PVPFNLVPSPKSLF-YLLLKLKKWISELFQGH--KKGFQEDAEMNKINE 806
Score = 36.6 bits (83), Expect = 0.20
Identities = 21/103 (20%), Positives = 49/103 (47%), Gaps = 1/103 (0%)
Query: 718 IPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKM-ERWPSTQEWIVISYIFTLG 776
I LGR + + + ++ + IG L++Y + K E + + +E + G
Sbjct: 625 ISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYIGAKQNEAFTTVEESFKTLFWAIFG 684
Query: 777 IEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMI 819
+ +++ ++++ K ++ + L +NVT +I +L + MI
Sbjct: 685 LSEVKSVVINYNHKFIENIGYVLYGVYNVTMVIVLLNMLIAMI 727
>gi|21314682 transient receptor potential cation channel, subfamily
V, member 6 [Homo sapiens]
Length = 725
Score = 52.8 bits (125), Expect = 3e-06
Identities = 41/138 (29%), Positives = 68/138 (49%), Gaps = 17/138 (12%)
Query: 856 LGPYVMMIGKMMI-DMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMI 914
LGP+ +MI KM+ D+M F +M VV++ F A I+F E+P +L Y
Sbjct: 475 LGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFY-IIFQTEDPE-ELGHFYDYPMALFS 532
Query: 915 YGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVF 974
E+F ID P N + LP ++ A + ++A +L++NLLIA+
Sbjct: 533 TFELFLTIIDGPANYN--------VDLP------FMYSITYAAFAIIATLLMLNLLIAMM 578
Query: 975 NNTFFEVKSISNQVWKFQ 992
+T + V +++W+ Q
Sbjct: 579 GDTHWRVAHERDELWRAQ 596
>gi|17505200 transient receptor potential cation channel, subfamily
V, member 5 [Homo sapiens]
Length = 729
Score = 50.4 bits (119), Expect = 1e-05
Identities = 38/138 (27%), Positives = 68/138 (49%), Gaps = 17/138 (12%)
Query: 856 LGPYVMMIGKMMI-DMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMI 914
LGP+ +MI KM+ D+M F +M VV++ F A I+F E+P+ L + Y
Sbjct: 475 LGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFY-IIFQTEDPT-SLGQFYDYPMALFT 532
Query: 915 YGEVFADQIDPPCGQNETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVF 974
E+F ID P + + LP ++ + + ++A +L++NL IA+
Sbjct: 533 TFELFLTVIDAPANYD--------VDLP------FMFSIVNFAFAIIATLLMLNLFIAMM 578
Query: 975 NNTFFEVKSISNQVWKFQ 992
+T + V +++W+ Q
Sbjct: 579 GDTHWRVAQERDELWRAQ 596
>gi|4507685 transient receptor potential cation channel, subfamily C,
member 1 [Homo sapiens]
Length = 759
Score = 46.6 bits (109), Expect = 2e-04
Identities = 68/322 (21%), Positives = 131/322 (40%), Gaps = 56/322 (17%)
Query: 729 NAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIV--ISYIFTLGIEKMREILMS 786
+ P +KF + +Y +L+L N LV E +T + I Y+ L I M + S
Sbjct: 347 HTPFMKFIIHGASYFTFLLLLNLYSLVYNEDKKNTMGPALERIDYLLILWIIGM---IWS 403
Query: 787 EPGKL-LQKVKVWLQEYWNVTDLIAILLFSVGMILRL------QDQPFRSD--------- 830
+ +L + ++ +L+E N + L+ L++ D R D
Sbjct: 404 DIKRLWYEGLEDFLEESRNQLSFVMNSLYLATFALKVVAHNKFHDFADRKDWDAFHPTLV 463
Query: 831 GRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQA 890
++ + Y+RL ++ + LGP + +G+M+ D F+ + L+VL SF +
Sbjct: 464 AEGLFAFANVLSYLRLFFMYTTSSILGPLQISMGQMLQDFGKFLGMFLLVLFSFTIGLTQ 523
Query: 891 IL---FPNEEPSWKLAKNIF----------------YMPYWMIYGEVFADQIDPPCGQNE 931
+ + ++E K IF + +W I+ E
Sbjct: 524 LYDKGYTSKEQ--KDCVGIFCEQQSNDTFHSFIGTCFALFWYIFSLAHVAIFVTRFSYGE 581
Query: 932 TREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKF 991
+ +++ I+ Y +V I+L LL+A+ + +F + + ++ WKF
Sbjct: 582 ELQ-------------SFVGAVIVGTYNVVVVIVLTKLLVAMLHKSFQLIANHEDKEWKF 628
Query: 992 QRYQLIMT-FHERPVLPPPLII 1012
R +L ++ F ++ LPPP I
Sbjct: 629 ARAKLWLSYFDDKCTLPPPFNI 650
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.402
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 59,756,115
Number of Sequences: 37866
Number of extensions: 2767256
Number of successful extensions: 13578
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 56
Number of HSP's successfully gapped in prelim test: 108
Number of HSP's that attempted gapping in prelim test: 12819
Number of HSP's gapped (non-prelim): 683
length of query: 1569
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1453
effective length of database: 13,855,062
effective search space: 20131405086
effective search space used: 20131405086
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.