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Search of human proteins with 153946401
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|153946401 BCL2/adenovirus E1B 19kD interacting protein 1
isoform BNIP1 [Homo sapiens]
(228 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|153946401 BCL2/adenovirus E1B 19kD interacting protein 1 isof... 435 e-122
gi|153946399 BCL2/adenovirus E1B 19kD interacting protein 1 isof... 414 e-116
gi|153946403 BCL2/adenovirus E1B 19kD interacting protein 1 isof... 351 3e-97
gi|153946405 BCL2/adenovirus E1B 19kD interacting protein 1 isof... 330 6e-91
gi|109255234 centrosomal protein 290kDa [Homo sapiens] 44 1e-04
gi|28195388 RAB11 family interacting protein 4 (class II) [Homo ... 44 1e-04
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 43 2e-04
gi|56550047 uveal autoantigen with coiled-coil domains and ankyr... 43 3e-04
gi|59850762 uveal autoantigen with coiled-coil domains and ankyr... 43 3e-04
gi|38044112 restin isoform b [Homo sapiens] 42 3e-04
gi|4506751 restin isoform a [Homo sapiens] 42 3e-04
gi|71061468 centromere protein E [Homo sapiens] 41 0.001
gi|190341068 forkhead-associated (FHA) phosphopeptide binding do... 40 0.001
gi|22749217 coiled-coil domain containing 63 [Homo sapiens] 40 0.002
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 39 0.003
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 39 0.003
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 39 0.003
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 39 0.003
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 39 0.003
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 39 0.003
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 39 0.003
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 39 0.003
gi|124249396 coiled-coil domain containing 30 [Homo sapiens] 39 0.004
gi|46049114 M-phase phosphoprotein 1 [Homo sapiens] 39 0.004
gi|48762942 huntingtin interacting protein-1-related [Homo sapiens] 39 0.005
gi|239750456 PREDICTED: similar to KIAA0655 protein [Homo sapiens] 39 0.005
gi|50658065 SMC4 structural maintenance of chromosomes 4-like 1 ... 39 0.005
gi|50658063 SMC4 structural maintenance of chromosomes 4-like 1 ... 39 0.005
gi|31982906 cingulin-like 1 [Homo sapiens] 38 0.006
gi|110347443 TATA element modulatory factor 1 [Homo sapiens] 38 0.008
>gi|153946401 BCL2/adenovirus E1B 19kD interacting protein 1 isoform
BNIP1 [Homo sapiens]
Length = 228
Score = 435 bits (1118), Expect = e-122
Identities = 228/228 (100%), Positives = 228/228 (100%)
Query: 1 MAAPQDVHVRICNQEIVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQD 60
MAAPQDVHVRICNQEIVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQD
Sbjct: 1 MAAPQDVHVRICNQEIVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQD 60
Query: 61 LEQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDL 120
LEQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDL
Sbjct: 61 LEQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDL 120
Query: 121 LRQRKTTKESLAQTSSTITESLMGISRMMAQQVQQSEEAMQSLVTSSRTILDANEEFKSM 180
LRQRKTTKESLAQTSSTITESLMGISRMMAQQVQQSEEAMQSLVTSSRTILDANEEFKSM
Sbjct: 121 LRQRKTTKESLAQTSSTITESLMGISRMMAQQVQQSEEAMQSLVTSSRTILDANEEFKSM 180
Query: 181 SGTIQLGRKLITKYNRRELTDKLLIFLALALFLATVLYIVKKRLFPFL 228
SGTIQLGRKLITKYNRRELTDKLLIFLALALFLATVLYIVKKRLFPFL
Sbjct: 181 SGTIQLGRKLITKYNRRELTDKLLIFLALALFLATVLYIVKKRLFPFL 228
>gi|153946399 BCL2/adenovirus E1B 19kD interacting protein 1 isoform
BNIP1-b [Homo sapiens]
Length = 271
Score = 414 bits (1064), Expect = e-116
Identities = 228/271 (84%), Positives = 228/271 (84%), Gaps = 43/271 (15%)
Query: 1 MAAPQDVHVRICNQEIVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQ- 59
MAAPQDVHVRICNQEIVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQ
Sbjct: 1 MAAPQDVHVRICNQEIVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQP 60
Query: 60 ------------------------------------------DLEQLAKEQDKESEKQLL 77
DLEQLAKEQDKESEKQLL
Sbjct: 61 VLYQRAFIWTASTFFFKLTYSLTDFSSTQHDFNSPTTPVTFSDLEQLAKEQDKESEKQLL 120
Query: 78 LQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDLLRQRKTTKESLAQTSST 137
LQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDLLRQRKTTKESLAQTSST
Sbjct: 121 LQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDLLRQRKTTKESLAQTSST 180
Query: 138 ITESLMGISRMMAQQVQQSEEAMQSLVTSSRTILDANEEFKSMSGTIQLGRKLITKYNRR 197
ITESLMGISRMMAQQVQQSEEAMQSLVTSSRTILDANEEFKSMSGTIQLGRKLITKYNRR
Sbjct: 181 ITESLMGISRMMAQQVQQSEEAMQSLVTSSRTILDANEEFKSMSGTIQLGRKLITKYNRR 240
Query: 198 ELTDKLLIFLALALFLATVLYIVKKRLFPFL 228
ELTDKLLIFLALALFLATVLYIVKKRLFPFL
Sbjct: 241 ELTDKLLIFLALALFLATVLYIVKKRLFPFL 271
>gi|153946403 BCL2/adenovirus E1B 19kD interacting protein 1 isoform
BNIP1-a [Homo sapiens]
Length = 194
Score = 351 bits (900), Expect = 3e-97
Identities = 194/228 (85%), Positives = 194/228 (85%), Gaps = 34/228 (14%)
Query: 1 MAAPQDVHVRICNQEIVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQD 60
MAAPQDVHVRICNQEIVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQD
Sbjct: 1 MAAPQDVHVRICNQEIVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQD 60
Query: 61 LEQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDL 120
LEQLAKEQDKESEKQLLLQEVENHKKQML
Sbjct: 61 LEQLAKEQDKESEKQLLLQEVENHKKQML------------------------------- 89
Query: 121 LRQRKTTKESLAQTSSTITESLMGISRMMAQQVQQSEEAMQSLVTSSRTILDANEEFKSM 180
RKTTKESLAQTSSTITESLMGISRMMAQQVQQSEEAMQSLVTSSRTILDANEEFKSM
Sbjct: 90 ---RKTTKESLAQTSSTITESLMGISRMMAQQVQQSEEAMQSLVTSSRTILDANEEFKSM 146
Query: 181 SGTIQLGRKLITKYNRRELTDKLLIFLALALFLATVLYIVKKRLFPFL 228
SGTIQLGRKLITKYNRRELTDKLLIFLALALFLATVLYIVKKRLFPFL
Sbjct: 147 SGTIQLGRKLITKYNRRELTDKLLIFLALALFLATVLYIVKKRLFPFL 194
>gi|153946405 BCL2/adenovirus E1B 19kD interacting protein 1 isoform
BNIP1-c [Homo sapiens]
Length = 237
Score = 330 bits (846), Expect = 6e-91
Identities = 194/271 (71%), Positives = 194/271 (71%), Gaps = 77/271 (28%)
Query: 1 MAAPQDVHVRICNQEIVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQ- 59
MAAPQDVHVRICNQEIVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQ
Sbjct: 1 MAAPQDVHVRICNQEIVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQP 60
Query: 60 ------------------------------------------DLEQLAKEQDKESEKQLL 77
DLEQLAKEQDKESEKQLL
Sbjct: 61 VLYQRAFIWTASTFFFKLTYSLTDFSSTQHDFNSPTTPVTFSDLEQLAKEQDKESEKQLL 120
Query: 78 LQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDLLRQRKTTKESLAQTSST 137
LQEVENHKKQML RKTTKESLAQTSST
Sbjct: 121 LQEVENHKKQML----------------------------------RKTTKESLAQTSST 146
Query: 138 ITESLMGISRMMAQQVQQSEEAMQSLVTSSRTILDANEEFKSMSGTIQLGRKLITKYNRR 197
ITESLMGISRMMAQQVQQSEEAMQSLVTSSRTILDANEEFKSMSGTIQLGRKLITKYNRR
Sbjct: 147 ITESLMGISRMMAQQVQQSEEAMQSLVTSSRTILDANEEFKSMSGTIQLGRKLITKYNRR 206
Query: 198 ELTDKLLIFLALALFLATVLYIVKKRLFPFL 228
ELTDKLLIFLALALFLATVLYIVKKRLFPFL
Sbjct: 207 ELTDKLLIFLALALFLATVLYIVKKRLFPFL 237
>gi|109255234 centrosomal protein 290kDa [Homo sapiens]
Length = 2479
Score = 43.9 bits (102), Expect = 1e-04
Identities = 39/186 (20%), Positives = 83/186 (44%), Gaps = 13/186 (6%)
Query: 7 VHVRICNQEIVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQDLEQLA- 65
V ++ C +I D E++ L ++I +S + N ++E+ + DL +
Sbjct: 463 VEIKNCKNQIKIRDREIEILTKEINKLELKISDFLDENEALRERVGLEPKTMIDLTEFRN 522
Query: 66 ----KEQDKESEKQLLLQEVENHKKQMLSNQASWR-------KANLTCKIAIDNLEKAEL 114
K+Q +E Q+LL+E+E+ +++ L + R K + T + ++L E
Sbjct: 523 SKHLKQQQYRAENQILLKEIESLEEERLDLKKKIRQMAQERGKRSATSGLTTEDLNLTEN 582
Query: 115 LQGGDLLRQRKTTKESLAQTSSTITESLMGISRMMAQQVQQSEEAMQSLVTSSRTILDAN 174
+ GD + +RK SL S +++ +SR + ++ + E + + + +
Sbjct: 583 ISQGDRISERKLDLLSLKNMSEAQSKNEF-LSRELIEKERDLERSRTVIAKFQNKLKELV 641
Query: 175 EEFKSM 180
EE K +
Sbjct: 642 EENKQL 647
Score = 37.4 bits (85), Expect = 0.011
Identities = 38/160 (23%), Positives = 75/160 (46%), Gaps = 19/160 (11%)
Query: 43 LNTKVKEKFQQLRHRIQDLEQLAKEQDKESE--KQLLL--QEVENHKKQMLSNQASWRKA 98
L ++ + +QL + ++LE + KE +KE + +QL L +E EN ++ +K
Sbjct: 113 LRNEICQLEKQLEQKDRELEDMEKELEKEKKVNEQLALRNEEAENENSKLRRENKRLKKK 172
Query: 99 N-LTCKIAIDNLEKAELLQGGDLLRQRKTTKESLAQTSSTITESLMGISRMMAQQVQQSE 157
N C+ I D +Q + KE+L ++ +S+ + +Q +
Sbjct: 173 NEQLCQDII------------DYQKQIDSQKETLLSRRGEDSDYRSQLSKKNYELIQYLD 220
Query: 158 EAMQSLVTSSRTILDANEEF-KSMSGTIQLGRKLITKYNR 196
E +Q+L ++ I N+E K++ ++Q K+ +YNR
Sbjct: 221 E-IQTLTEANEKIEVQNQEMRKNLEESVQEMEKMTDEYNR 259
Score = 32.7 bits (73), Expect = 0.26
Identities = 24/80 (30%), Positives = 42/80 (52%), Gaps = 10/80 (12%)
Query: 9 VRICNQEIVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQDLEQLAKEQ 68
+R+ N ++ K E+ I+ +D SG S + + + QL+ +I+DLE K
Sbjct: 2344 LRLANHQLDKEKAELIHQIEANKDQSGAESTIPDAD--------QLKEKIKDLETQLKMS 2395
Query: 69 DKESEKQLLLQEVENHKKQM 88
D EKQ L +E++ KK++
Sbjct: 2396 D--LEKQHLKEEIKKLKKEL 2413
>gi|28195388 RAB11 family interacting protein 4 (class II) [Homo
sapiens]
Length = 637
Score = 43.5 bits (101), Expect = 1e-04
Identities = 38/153 (24%), Positives = 70/153 (45%), Gaps = 17/153 (11%)
Query: 42 ELNTKVKEKFQQLRHRIQDLEQLAKEQDKESEKQLLLQEVENHKKQ--MLSNQASWRKAN 99
+L +K+K++ QL HR+ +LE++ K+Q+ +E Q L +E H++ L + +
Sbjct: 363 DLKSKLKQENTQLVHRVHELEEMVKDQETTAE-QALEEEARRHREAYGKLEREKATEVEL 421
Query: 100 LTCKIAIDNLEKAEL--------LQGGDLLRQRKTTKESLAQTSSTITESLMGISRMMAQ 151
L ++ E EL Q L +R+ + L TS + + + RMM +
Sbjct: 422 LNARVQQLEEENTELRTTVTRLKSQTEKLDEERQRMSDRLEDTSLRLKDEMDLYKRMMDK 481
Query: 152 ------QVQQSEEAMQSLVTSSRTILDANEEFK 178
+ Q+ EA Q L+ R L+ + +K
Sbjct: 482 LRQNRLEFQKEREATQELIEDLRKELEHLQMYK 514
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 43.1 bits (100), Expect = 2e-04
Identities = 47/203 (23%), Positives = 90/203 (44%), Gaps = 24/203 (11%)
Query: 8 HVRICNQEIVKFDLEVKALIQDIRDCSGPLS----ALTELNTKVKEKFQQLRHRIQDLEQ 63
H+R ++ + + +D+ SG LS ALT++ T++ E+ ++ LE
Sbjct: 1386 HLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEM 1445
Query: 64 LAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDLLRQ 123
AKE D E KQL ++ E +K + S K + K+ +A L+ + L++
Sbjct: 1446 QAKEHD-ERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKL------QAALISRKEALKE 1498
Query: 124 RKTTKESLAQTSSTI---TESLMGISRMMAQQVQQS----------EEAMQSLVTSSRTI 170
K+ +E L+ TI T+SL + ++ Q ++ +E L+T
Sbjct: 1499 NKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRS 1558
Query: 171 LDANEEFKSMSGTIQLGRKLITK 193
L N+ S +++L + +T+
Sbjct: 1559 LLENQSLSSSCESLKLALEGLTE 1581
Score = 38.5 bits (88), Expect = 0.005
Identities = 43/184 (23%), Positives = 84/184 (45%), Gaps = 18/184 (9%)
Query: 22 EVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQDLEQLAKEQDKESEKQLLLQEV 81
E + L+Q + S + + V+++ Q+L +++ E KE +K+ ++ QE+
Sbjct: 1614 EYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQE--AEQEM 1671
Query: 82 ENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGGD--------LLRQRKTTKESLA- 132
E K++M S ++ L + D L +AE+ GD LL + KE L
Sbjct: 1672 EEMKEKMRKFAKSKQQKILELEEENDRL-RAEVHPAGDTAKECMETLLSSNASMKEELER 1730
Query: 133 -----QTSSTITESLMGISRMMAQQVQQSEEAMQSLVTSSRTILDANEEFKSMSGTIQLG 187
+T S +SLM ++++VQ + ++ V S + L+A E+ + + + G
Sbjct: 1731 VKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNV-SKQANLEATEKHDNQTNVTEEG 1789
Query: 188 RKLI 191
+ I
Sbjct: 1790 TQSI 1793
Score = 32.3 bits (72), Expect = 0.34
Identities = 36/173 (20%), Positives = 78/173 (45%), Gaps = 16/173 (9%)
Query: 13 NQEIVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQDLEQLAKEQDKES 72
+Q I + E L ++IR + L N K+ + Q R +DL Q+ +D +
Sbjct: 2495 DQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYR---EDLNQVITIKDSQQ 2551
Query: 73 EKQLLLQ-----EVENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDLLRQRKTT 127
++ L +Q E+EN ++ +AN + + + L++ + DL ++ ++
Sbjct: 2552 KQLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQE----EKQDLSKEIESL 2607
Query: 128 KESLAQTSSTIT----ESLMGISRMMAQQVQQSEEAMQSLVTSSRTILDANEE 176
K S++Q + +T E +G+ + ++ + +L +SS+ + EE
Sbjct: 2608 KVSISQLTRQVTALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEE 2660
Score = 31.6 bits (70), Expect = 0.59
Identities = 34/136 (25%), Positives = 58/136 (42%), Gaps = 14/136 (10%)
Query: 37 LSALTELNTKVKEKFQQLRHRIQDLEQLAKEQDK--------ESEKQLLLQEVENHKKQM 88
LS L +LN ++ K +QL H LE + ++E+ L E+E +K
Sbjct: 2800 LSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSE 2859
Query: 89 LSNQASWRKANLTCKIAIDNLEKAELLQGGD---LLRQRKTTKESLAQTSSTITESLMGI 145
Q S + + T + +L+KA D LL++ K ++ Q + ITE +
Sbjct: 2860 EGKQRSAAQPS-TSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITE--LHP 2916
Query: 146 SRMMAQQVQQSEEAMQ 161
+ Q+ Q +A Q
Sbjct: 2917 LKAQLQEYQDKTKAFQ 2932
Score = 30.4 bits (67), Expect = 1.3
Identities = 41/181 (22%), Positives = 78/181 (43%), Gaps = 21/181 (11%)
Query: 40 LTELNTKVKEKFQQ----LRHRIQDLEQLAKEQDKESEKQLLLQEVENHKKQMLSNQASW 95
LT LN ++E Q L Q EQL+K DK S ++ + E HK Q S
Sbjct: 104 LTSLNKYIEEMKAQGGTVLPTEPQSEEQLSK-HDKSSTEEEMEIEKIKHKLQEKEELIST 162
Query: 96 RKANLTCKIAIDNLEKAELLQGGDLLRQRKTTKE---SLAQTSSTITESLMGISRMMAQ- 151
+A LT A + + ++ +++Q+ KE S Q + T++ +++ +
Sbjct: 163 LQAQLTQAQAEQPAQSSTEMEEFVMMKQQLQEKEEFISTLQAQLSQTQAEQAAQQVVREK 222
Query: 152 ------QVQQSEEAMQSLVTSSRTILDANEEFKSMSGTIQ------LGRKLITKYNRREL 199
QV+ E+ + LVT + + ++ + + ++ +GR + ++EL
Sbjct: 223 DARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQEL 282
Query: 200 T 200
T
Sbjct: 283 T 283
Score = 29.6 bits (65), Expect = 2.2
Identities = 40/196 (20%), Positives = 83/196 (42%), Gaps = 12/196 (6%)
Query: 13 NQEIVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQDLE---QLAKEQD 69
N+E +E+K L + + S A E + E L+ ++ Q++KE +
Sbjct: 918 NEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKE-E 976
Query: 70 KESEKQLLLQEVENHKKQMLS-----NQASWRKANLTCKIA-IDNLEKAELLQGGDLLRQ 123
+ E LL +E E K+++ + + R + L ++A + + K E+ +
Sbjct: 977 LQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDESKKEIPLSETERGE 1036
Query: 124 RKTTKESLAQTSSTITESLMGISRMMAQQVQQSEEAMQSLVTSSRTILDANEEFKSMSGT 183
+ KE+ + +T I + Q + + E +Q + L A E+F+++
Sbjct: 1037 VEEDKENKEYSEKCVTSKCQEIEIYLKQTISEKEVELQHIRKDLEEKLAAEEQFQAL--V 1094
Query: 184 IQLGRKLITKYNRREL 199
Q+ + L K N+ +L
Sbjct: 1095 KQMNQTLQDKTNQIDL 1110
Score = 29.6 bits (65), Expect = 2.2
Identities = 33/155 (21%), Positives = 57/155 (36%), Gaps = 7/155 (4%)
Query: 44 NTKVKEKFQQLRHRIQDLEQLAKEQDKE-----SEKQLLLQEVENHKKQMLSNQASWRKA 98
N K+KE+ + LR + DL + D E + ++ ++ +KQ+L Q K
Sbjct: 2505 NNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKE 2564
Query: 99 NLTCKIAIDNLEKAELLQGGDLLRQRKTTKESLAQTSSTITESLMGISRMMAQQVQQSEE 158
++ K DL R +E S I + IS++ Q EE
Sbjct: 2565 LENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEE 2624
Query: 159 AMQSLVTSSRTILDANEEFKSMSGTIQLGRKLITK 193
L + + + EE +S +K I +
Sbjct: 2625 GTLGLYHAQLKVKE--EEVHRLSALFSSSQKRIAE 2657
Score = 27.7 bits (60), Expect = 8.5
Identities = 38/177 (21%), Positives = 77/177 (43%), Gaps = 15/177 (8%)
Query: 22 EVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRH---RIQDLEQLAKEQDKESEKQLL- 77
E L+ I G L L E TK+ QQ++ R+ L++ A+E+ + E++L+
Sbjct: 1869 EKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLMN 1928
Query: 78 -LQEVENHKKQMLSNQASWRKANLTCKIAIDNLEK--AELLQGGDLLRQRKTTKESLAQT 134
L E+ + + N + + NL+K +EL + L + KT ES +
Sbjct: 1929 QLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVES--EI 1986
Query: 135 SSTITESLMGI-----SRMMAQQVQQ-SEEAMQSLVTSSRTILDANEEFKSMSGTIQ 185
E + G ++ A+++Q+ +E Q + + + E+ ++ T++
Sbjct: 1987 RKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVK 2043
>gi|56550047 uveal autoantigen with coiled-coil domains and ankyrin
repeats isoform 2 [Homo sapiens]
Length = 1403
Score = 42.7 bits (99), Expect = 3e-04
Identities = 44/200 (22%), Positives = 89/200 (44%), Gaps = 20/200 (10%)
Query: 14 QEIVKFDLEVKAL---IQDIRDCS----GPLSALTELNTKVKEKFQQLRHRIQDLEQLAK 66
+EIV E+KA + I++C P+ + E K K ++L+ ++ EQ K
Sbjct: 945 EEIVTLHAEIKAQKKELDTIQECIKVKYAPIVSFEECERKFKATEKELKDQLS--EQTQK 1002
Query: 67 EQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDLLRQRK- 125
E E + QE + KK++ + Q R + + + + +E+A + +L +Q K
Sbjct: 1003 YSVSEEEVKKNKQENDKLKKEIFTLQKDLRDKTVLIEKSHE-MERALSRKTDELNKQLKD 1061
Query: 126 ---------TTKESLAQTSSTITESLMGISRMMAQQVQQSEEAMQSLVTSSRTILDANEE 176
KE L + ++ T ++ + ++ +Q E+ + + TI + EE
Sbjct: 1062 LSQKYTEVKNVKEKLVEENAKQTSEILAVQNLLQKQHVPLEQVEALKKSLNGTIENLKEE 1121
Query: 177 FKSMSGTIQLGRKLITKYNR 196
KSM + ++ +TK ++
Sbjct: 1122 LKSMQRCYEKEQQTVTKLHQ 1141
Score = 28.5 bits (62), Expect = 5.0
Identities = 30/147 (20%), Positives = 63/147 (42%), Gaps = 12/147 (8%)
Query: 22 EVKALIQDIR-DCSGPLSALTELNTKVKEKFQQLRHRIQDLEQLAKEQDKESEKQLLLQE 80
E+K ++D++ G + + +L ++K+ + +D +L E++K +K+L + E
Sbjct: 528 ELKDQLKDLKVKYEGASAEVGKLRNQIKQNEMIVEEFKRDEGKLI-EENKRLQKELSMCE 586
Query: 81 VENHKK----QMLSNQASWRKANLTCKIAIDNLEKAELLQGGDLLRQRKTTKESLAQTSS 136
+E KK + QA A L I + E + ++ + K E +
Sbjct: 587 MEREKKGRKVTEMEGQAKELSAKLALSIPAEKFENMKSSLSNEVNEKAKKLVEMEREHEK 646
Query: 137 TITE------SLMGISRMMAQQVQQSE 157
+++E L + +AQ V+ E
Sbjct: 647 SLSEIRQLKRELENVKAKLAQHVKPEE 673
>gi|59850762 uveal autoantigen with coiled-coil domains and ankyrin
repeats isoform 1 [Homo sapiens]
Length = 1416
Score = 42.7 bits (99), Expect = 3e-04
Identities = 44/200 (22%), Positives = 89/200 (44%), Gaps = 20/200 (10%)
Query: 14 QEIVKFDLEVKAL---IQDIRDCS----GPLSALTELNTKVKEKFQQLRHRIQDLEQLAK 66
+EIV E+KA + I++C P+ + E K K ++L+ ++ EQ K
Sbjct: 958 EEIVTLHAEIKAQKKELDTIQECIKVKYAPIVSFEECERKFKATEKELKDQLS--EQTQK 1015
Query: 67 EQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDLLRQRK- 125
E E + QE + KK++ + Q R + + + + +E+A + +L +Q K
Sbjct: 1016 YSVSEEEVKKNKQENDKLKKEIFTLQKDLRDKTVLIEKSHE-MERALSRKTDELNKQLKD 1074
Query: 126 ---------TTKESLAQTSSTITESLMGISRMMAQQVQQSEEAMQSLVTSSRTILDANEE 176
KE L + ++ T ++ + ++ +Q E+ + + TI + EE
Sbjct: 1075 LSQKYTEVKNVKEKLVEENAKQTSEILAVQNLLQKQHVPLEQVEALKKSLNGTIENLKEE 1134
Query: 177 FKSMSGTIQLGRKLITKYNR 196
KSM + ++ +TK ++
Sbjct: 1135 LKSMQRCYEKEQQTVTKLHQ 1154
Score = 28.5 bits (62), Expect = 5.0
Identities = 30/147 (20%), Positives = 63/147 (42%), Gaps = 12/147 (8%)
Query: 22 EVKALIQDIR-DCSGPLSALTELNTKVKEKFQQLRHRIQDLEQLAKEQDKESEKQLLLQE 80
E+K ++D++ G + + +L ++K+ + +D +L E++K +K+L + E
Sbjct: 541 ELKDQLKDLKVKYEGASAEVGKLRNQIKQNEMIVEEFKRDEGKLI-EENKRLQKELSMCE 599
Query: 81 VENHKK----QMLSNQASWRKANLTCKIAIDNLEKAELLQGGDLLRQRKTTKESLAQTSS 136
+E KK + QA A L I + E + ++ + K E +
Sbjct: 600 MEREKKGRKVTEMEGQAKELSAKLALSIPAEKFENMKSSLSNEVNEKAKKLVEMEREHEK 659
Query: 137 TITE------SLMGISRMMAQQVQQSE 157
+++E L + +AQ V+ E
Sbjct: 660 SLSEIRQLKRELENVKAKLAQHVKPEE 686
>gi|38044112 restin isoform b [Homo sapiens]
Length = 1392
Score = 42.4 bits (98), Expect = 3e-04
Identities = 46/201 (22%), Positives = 86/201 (42%), Gaps = 12/201 (5%)
Query: 13 NQEIVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQDLEQLAKEQDKES 72
NQ++ +F E++ L Q S LSAL E N K+ E+ + R + ++L +E+ +
Sbjct: 1102 NQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEVTSHQKLEEERSVLN 1161
Query: 73 EKQLLLQEVE-------NHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDLLRQRK 125
+ L +++ E + +K L S A LT K A E +L +LR
Sbjct: 1162 NQLLEMKKRESKFIKDADEEKASLQKSISITSALLTEKDA----ELEKLRNEVTVLRGEN 1217
Query: 126 TTKESLAQTSSTITESLMGIS-RMMAQQVQQSEEAMQSLVTSSRTILDANEEFKSMSGTI 184
+ +SL T+ + + ++ ++Q E Q +S T A+E+ ++ I
Sbjct: 1218 ASAKSLHSVVQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDTQADEDERAQESQI 1277
Query: 185 QLGRKLITKYNRRELTDKLLI 205
+I R+ K+ +
Sbjct: 1278 DFLNSVIVDLQRKNQDLKMKV 1298
Score = 33.9 bits (76), Expect = 0.12
Identities = 41/194 (21%), Positives = 83/194 (42%), Gaps = 40/194 (20%)
Query: 40 LTELNTKVKEKFQQLRHRIQDLEQLAKEQDKESEKQL------LLQEVENHKKQMLSNQA 93
L + K+K ++ +Q+LE+L K+ DK Q +++++ K + L++
Sbjct: 1005 LLDTEDKLKGAREENSGLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLE 1064
Query: 94 SWRKANLTCKIAIDNLEK------AELLQGGDLL-----------RQRKTTKESLAQTSS 136
++ N + +D L++ EL + +LL ++ +T K++ AQ S
Sbjct: 1065 DTKQTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQ 1124
Query: 137 TIT---------ESLMGISRMMAQQVQQSEE--------AMQSLVTSSRTILDANEEFKS 179
++ +G SR Q+ EE ++ S+ I DA+EE S
Sbjct: 1125 QLSALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKAS 1184
Query: 180 MSGTIQLGRKLITK 193
+ +I + L+T+
Sbjct: 1185 LQKSISITSALLTE 1198
Score = 28.9 bits (63), Expect = 3.8
Identities = 33/190 (17%), Positives = 81/190 (42%), Gaps = 23/190 (12%)
Query: 9 VRICNQEIVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQDLEQLAKEQ 68
++I ++ + E ++ + +++ L E + ++LR + D+E +E+
Sbjct: 807 LQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREK 866
Query: 69 DKESEKQLLLQE-VENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDLLRQRKTT 127
D+ E+ + +E +EN +++ K++ DN ++L + D LR ++
Sbjct: 867 DEREEQLIKAKEKLENDIAEIM-------------KMSGDN--SSQLTKMNDELRLKERD 911
Query: 128 KESLAQTSSTITESLMGISRMMAQQVQQSEEAMQSLVTSSRTILDANEEFKSMSGTI-QL 186
E L + E+ + + + ++E++ Q EE K + + L
Sbjct: 912 VEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKH------EEEKKELERKLSDL 965
Query: 187 GRKLITKYNR 196
+K+ T +N+
Sbjct: 966 EKKMETSHNQ 975
Score = 28.5 bits (62), Expect = 5.0
Identities = 35/159 (22%), Positives = 70/159 (44%), Gaps = 26/159 (16%)
Query: 12 CNQE---IVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQDLEQLAKEQ 68
CN++ I F ++KA + + D A +E +++K+ QQL + ++ L E+
Sbjct: 706 CNEQTKVIDNFTSQLKATEEKLLDLDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEK 765
Query: 69 DKESEK-QLLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDLLRQRKTT 127
+ ES K + +E++ + ++ + Q +NL + ++ L ++ +
Sbjct: 766 NAESSKASSITRELQGRELKLTNLQ--------------ENLSEVSQVK-ETLEKELQIL 810
Query: 128 KESLAQTSSTITESLMGISRMMAQQV---QQSEEAMQSL 163
KE A+ S E + + R M + V Q EE L
Sbjct: 811 KEKFAEAS----EEAVSVQRSMQETVNKLHQKEEQFNML 845
>gi|4506751 restin isoform a [Homo sapiens]
Length = 1427
Score = 42.4 bits (98), Expect = 3e-04
Identities = 46/201 (22%), Positives = 86/201 (42%), Gaps = 12/201 (5%)
Query: 13 NQEIVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQDLEQLAKEQDKES 72
NQ++ +F E++ L Q S LSAL E N K+ E+ + R + ++L +E+ +
Sbjct: 1137 NQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEVTSHQKLEEERSVLN 1196
Query: 73 EKQLLLQEVE-------NHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDLLRQRK 125
+ L +++ E + +K L S A LT K A E +L +LR
Sbjct: 1197 NQLLEMKKRESKFIKDADEEKASLQKSISITSALLTEKDA----ELEKLRNEVTVLRGEN 1252
Query: 126 TTKESLAQTSSTITESLMGIS-RMMAQQVQQSEEAMQSLVTSSRTILDANEEFKSMSGTI 184
+ +SL T+ + + ++ ++Q E Q +S T A+E+ ++ I
Sbjct: 1253 ASAKSLHSVVQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDTQADEDERAQESQI 1312
Query: 185 QLGRKLITKYNRRELTDKLLI 205
+I R+ K+ +
Sbjct: 1313 DFLNSVIVDLQRKNQDLKMKV 1333
Score = 33.9 bits (76), Expect = 0.12
Identities = 41/194 (21%), Positives = 83/194 (42%), Gaps = 40/194 (20%)
Query: 40 LTELNTKVKEKFQQLRHRIQDLEQLAKEQDKESEKQL------LLQEVENHKKQMLSNQA 93
L + K+K ++ +Q+LE+L K+ DK Q +++++ K + L++
Sbjct: 1040 LLDTEDKLKGAREENSGLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLE 1099
Query: 94 SWRKANLTCKIAIDNLEK------AELLQGGDLL-----------RQRKTTKESLAQTSS 136
++ N + +D L++ EL + +LL ++ +T K++ AQ S
Sbjct: 1100 DTKQTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQ 1159
Query: 137 TIT---------ESLMGISRMMAQQVQQSEE--------AMQSLVTSSRTILDANEEFKS 179
++ +G SR Q+ EE ++ S+ I DA+EE S
Sbjct: 1160 QLSALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKAS 1219
Query: 180 MSGTIQLGRKLITK 193
+ +I + L+T+
Sbjct: 1220 LQKSISITSALLTE 1233
Score = 28.9 bits (63), Expect = 3.8
Identities = 33/190 (17%), Positives = 81/190 (42%), Gaps = 23/190 (12%)
Query: 9 VRICNQEIVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQDLEQLAKEQ 68
++I ++ + E ++ + +++ L E + ++LR + D+E +E+
Sbjct: 842 LQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREK 901
Query: 69 DKESEKQLLLQE-VENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDLLRQRKTT 127
D+ E+ + +E +EN +++ K++ DN ++L + D LR ++
Sbjct: 902 DEREEQLIKAKEKLENDIAEIM-------------KMSGDN--SSQLTKMNDELRLKERD 946
Query: 128 KESLAQTSSTITESLMGISRMMAQQVQQSEEAMQSLVTSSRTILDANEEFKSMSGTI-QL 186
E L + E+ + + + ++E++ Q EE K + + L
Sbjct: 947 VEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKH------EEEKKELERKLSDL 1000
Query: 187 GRKLITKYNR 196
+K+ T +N+
Sbjct: 1001 EKKMETSHNQ 1010
Score = 28.5 bits (62), Expect = 5.0
Identities = 35/159 (22%), Positives = 70/159 (44%), Gaps = 26/159 (16%)
Query: 12 CNQE---IVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQDLEQLAKEQ 68
CN++ I F ++KA + + D A +E +++K+ QQL + ++ L E+
Sbjct: 741 CNEQTKVIDNFTSQLKATEEKLLDLDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEK 800
Query: 69 DKESEK-QLLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDLLRQRKTT 127
+ ES K + +E++ + ++ + Q +NL + ++ L ++ +
Sbjct: 801 NAESSKASSITRELQGRELKLTNLQ--------------ENLSEVSQVK-ETLEKELQIL 845
Query: 128 KESLAQTSSTITESLMGISRMMAQQV---QQSEEAMQSL 163
KE A+ S E + + R M + V Q EE L
Sbjct: 846 KEKFAEAS----EEAVSVQRSMQETVNKLHQKEEQFNML 880
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 40.8 bits (94), Expect = 0.001
Identities = 42/153 (27%), Positives = 71/153 (46%), Gaps = 17/153 (11%)
Query: 14 QEIVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQDLEQLAKEQDKESE 73
QEIV E I+ + S L E+ K+KEK QQL+ + Q QL Q++ SE
Sbjct: 1098 QEIVA--QEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQ---QLLNVQEEMSE 1152
Query: 74 KQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGG-----DLLRQRKTTK 128
Q + E+EN K ++ + + + + + LE A+ L + ++RK K
Sbjct: 1153 MQKKINEIENLKNELKNKELTLE------HMETERLELAQKLNENYEEVKSITKERKVLK 1206
Query: 129 ESLAQTSSTITESLMGISRMMAQQVQQSEEAMQ 161
E L ++ T + L G R + Q++E ++
Sbjct: 1207 E-LQKSFETERDHLRGYIREIEATGLQTKEELK 1238
Score = 35.0 bits (79), Expect = 0.053
Identities = 40/176 (22%), Positives = 80/176 (45%), Gaps = 22/176 (12%)
Query: 40 LTELNTKVKEKFQQLRHRIQDLEQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRK-- 97
L N K++EK Q+L+ L L K+ ++ +K + E+E KKQ+ + K
Sbjct: 1811 LENSNAKLQEKIQELKANEHQLITLKKDVNETQKK---VSEMEQLKKQIKDQSLTLSKLE 1867
Query: 98 ---ANLTCKIAIDNLEKAELLQGGDLLR--------QRKTTKESLAQTSSTITE--SLMG 144
NL K+ + E +++ D LR +R KESL +T + E +
Sbjct: 1868 IENLNLAQKLHENLEEMKSVMKERDNLRRVEETLKLERDQLKESLQETKARDLEIQQELK 1927
Query: 145 ISRMMAQQVQQSEEAMQSLVTSSR-TILDANEEFKSMSGTIQLGRKLITKYNRREL 199
+RM++++ +++ + ++ ++ I D ++ +Q K I + ++EL
Sbjct: 1928 TARMLSKEHKETVDKLREKISEKTIQISDIQKDLDKSKDELQ---KKIQELQKKEL 1980
Score = 34.7 bits (78), Expect = 0.069
Identities = 38/176 (21%), Positives = 79/176 (44%), Gaps = 15/176 (8%)
Query: 15 EIVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQDLEQLAKEQDKESEK 74
E+V + V+ L+++I L+ ++FQ + D EQ K +E+E+
Sbjct: 783 EVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEENER 842
Query: 75 QLLLQEVENHKK--QMLSNQASWRKANLTCKIAIDNLEKAELLQGGDLLRQRKTTKESLA 132
+ QE+ N K Q + K L+ K + EK +Q + L + + KE L
Sbjct: 843 --MNQEIVNLSKEAQKFDSSLGALKTELSYKTQ-ELQEKTREVQ--ERLNEMEQLKEQLE 897
Query: 133 QTSSTITESLMGISRMMAQQVQQSEEAMQSLVTSSRTILDANEEFKSMSGTIQLGR 188
ST+ +++ ++ +++QQ+ E + +T+ ++ K + ++Q+ R
Sbjct: 898 NRDSTL-QTVEREKTLITEKLQQTLEEV-------KTLTQEKDDLKQLQESLQIER 945
Score = 31.6 bits (70), Expect = 0.59
Identities = 36/155 (23%), Positives = 74/155 (47%), Gaps = 9/155 (5%)
Query: 51 FQQLRHRIQDLEQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLE 110
++QLR +++E KE++ E + L ++ + ++ L ++ S K NL + N +
Sbjct: 514 YEQLRTEKEEMELKLKEKNDLDEFEALERKTKKDQEMQLIHEISNLK-NLVKHAEVYNQD 572
Query: 111 -KAELLQGGDLLRQRKTTKESLAQ--TSSTITESLMGISRMMAQQVQQSEEAMQSLVTSS 167
+ EL +LLR+++ + L + S + M +S + + ++ ++ Q+L +
Sbjct: 573 LENELSSKVELLREKEDQIKKLQEYIDSQKLENIKMDLSYSL-ESIEDPKQMKQTLFDAE 631
Query: 168 RTILDANEEFKSM-SGTIQLGRK---LITKYNRRE 198
LDA E + S ++L K L T Y + E
Sbjct: 632 TVALDAKRESAFLRSENLELKEKMKELATTYKQME 666
Score = 31.2 bits (69), Expect = 0.77
Identities = 38/192 (19%), Positives = 81/192 (42%), Gaps = 21/192 (10%)
Query: 15 EIVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQDLEQLAKEQDKESEK 74
E+ EV+ L ++I+D S L +T K+ F ++ H KES
Sbjct: 748 ELKSLPSEVERLRKEIQDKSEELHIITSEKDKL---FSEVVH-------------KESRV 791
Query: 75 QLLLQEVENHKKQMLSNQASWRKANLTCK----IAIDNLEKAEL-LQGGDLLRQRKTTKE 129
Q LL+E+ K + + Q++++ + + + +D +K ++ L+ + + Q
Sbjct: 792 QGLLEEIGKTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLS 851
Query: 130 SLAQTSSTITESLMGISRMMAQQVQQSEEAMQSLVTSSRTILDANEEFKSMSGTIQLGRK 189
AQ + +L Q++Q+ +Q + + + E S T++ +
Sbjct: 852 KEAQKFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKT 911
Query: 190 LITKYNRRELTD 201
LIT+ ++ L +
Sbjct: 912 LITEKLQQTLEE 923
Score = 30.4 bits (67), Expect = 1.3
Identities = 34/157 (21%), Positives = 65/157 (41%), Gaps = 36/157 (22%)
Query: 42 ELNTKVKEKFQQLRHRIQDLEQLAKEQDKESEKQLLLQEVENHKKQM------------- 88
E+ +KEK + R+Q+ Q+ ++Q KE+ K+++ + E+ +K+
Sbjct: 1584 EIQIMIKEKEEM--KRVQEALQIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQE 1641
Query: 89 -------LSNQASWRKANLTCKIAIDNLEKAELLQGGDLLRQRKTTKESLAQTSSTITES 141
L Q +K NL I +N+ ++L +L R TKE +
Sbjct: 1642 KMCEIEHLKEQFETQKLNLE-NIETENIRLTQILH-ENLEEMRSVTKE---------RDD 1690
Query: 142 LMGISRMMAQQVQQSEEAMQSLVTSSRTILDANEEFK 178
L + + + Q +E ++ +T L+ EE K
Sbjct: 1691 LRSVEETLKVERDQLKENLRETITRD---LEKQEELK 1724
Score = 29.3 bits (64), Expect = 2.9
Identities = 39/191 (20%), Positives = 82/191 (42%), Gaps = 24/191 (12%)
Query: 22 EVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQDLEQLAKEQDKESEKQLLLQEV 81
EV+ + +++ A ++ K +L +R+Q+ ++ + KE E+ +QE
Sbjct: 1542 EVQEKVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEA 1601
Query: 82 ---------ENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDLLRQRKTTKESLA 132
EN K+ + + S K K+ N + ++ + L Q +T K +L
Sbjct: 1602 LQIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLE 1661
Query: 133 QTSSTITESLMGISRMMAQQVQQSEEAMQSLVTSSRTILDANEEFKSMSGTIQLGRKLIT 192
TE++ + Q + ++ E M+S VT R ++ +S+ T+++ R +
Sbjct: 1662 NIE---TENI-----RLTQILHENLEEMRS-VTKER------DDLRSVEETLKVERDQLK 1706
Query: 193 KYNRRELTDKL 203
+ R +T L
Sbjct: 1707 ENLRETITRDL 1717
>gi|190341068 forkhead-associated (FHA) phosphopeptide binding
domain 1 [Homo sapiens]
Length = 1412
Score = 40.4 bits (93), Expect = 0.001
Identities = 48/201 (23%), Positives = 87/201 (43%), Gaps = 12/201 (5%)
Query: 13 NQEIVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQDLEQLAKEQDKES 72
N EI E + L +D SG +S+L + E+ QQL+ + L+ K++D +
Sbjct: 325 NSEITSLKNEGENLKRDNAITSGMVSSLQKDILAKDEQVQQLKEEVSHLKSQNKDKDHQL 384
Query: 73 EK-----QLLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDLLRQRKTT 127
E +L +E++ +A ++ L CK I ++EK E+ + LR+ T
Sbjct: 385 EALGSRCSVLKEELKQEDAHRELREAQEKELKL-CKTQIQDMEK-EMKKLRAELRKSCTE 442
Query: 128 KESLAQT---SSTITESLMGISRMMAQQVQQSEEAMQSLVTSSRTILDANEEFKSMSGTI 184
+ +++T S + E L SR Q+Q+ + + + E F+S
Sbjct: 443 QSVISRTLREKSKVEEKLQEDSRRKLLQLQEMGNRESVIKINLERAVGQLEHFRSQVIKA 502
Query: 185 QLGRKLITKYNRRELTDKLLI 205
GR + + +TD+ LI
Sbjct: 503 TYGR--AKPFRDKPVTDQQLI 521
Score = 36.6 bits (83), Expect = 0.018
Identities = 41/183 (22%), Positives = 85/183 (46%), Gaps = 20/183 (10%)
Query: 24 KALIQDIRDCSGPLSALTELNT-----KVKEKFQQLRHRIQDLEQLAKEQDKESEKQLLL 78
K +QD+ + ++E N K KE ++ + ++QDLE +Q +E E +
Sbjct: 781 KRKVQDLENHLTQQKEISESNIAYEKRKAKEAMEKEKKKVQDLENRLTKQKEELELKEQK 840
Query: 79 QEVENHK-KQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDLLRQRKTTKESLAQTSST 137
++V N+K L+ +K T + ++L L+ + L + +TTK T
Sbjct: 841 EDVLNNKLSDALAMVEETQKTKATESLKAESL----ALKLNETLAELETTK-----TKMI 891
Query: 138 ITESLMGISRMMAQQVQQSEEAMQSLVTSSRTILDANEEFKSMSGTI-QLGRKL--ITKY 194
+ E + + + M + +Q +E+ + I++ E+ K + TI L KL +T++
Sbjct: 892 MVEERLILQQKMVKALQDEQESQRH--GFEEEIMEYKEQIKQHAQTIVSLEEKLQKVTQH 949
Query: 195 NRR 197
+++
Sbjct: 950 HKK 952
Score = 35.4 bits (80), Expect = 0.041
Identities = 31/149 (20%), Positives = 66/149 (44%), Gaps = 15/149 (10%)
Query: 40 LTELNTKVKEKFQQLRHRIQDLEQLAKEQDKESEKQLLLQ--------EVENHKKQMLSN 91
+T+ + KE ++ R R+Q+LE L +Q K K + + E E + Q L
Sbjct: 694 ITQERNRAKETLEEERKRMQELESLLAQQKKALAKSITQEKNRVKEALEEEQTRVQELEE 753
Query: 92 QASWRKANLTCKIAIDNLEKAELLQGGDLLRQRKTTKESLAQTSSTITESLMGISRMMAQ 151
+ + +K L IA + + E L+ +++ E+ I+ES + + A+
Sbjct: 754 RLARQKEVLESSIAHEKRKAKEALESE---KRKVQDLENHLTQQKEISESNIAYEKRKAK 810
Query: 152 QVQQSE----EAMQSLVTSSRTILDANEE 176
+ + E + +++ +T + L+ E+
Sbjct: 811 EAMEKEKKKVQDLENRLTKQKEELELKEQ 839
>gi|22749217 coiled-coil domain containing 63 [Homo sapiens]
Length = 563
Score = 39.7 bits (91), Expect = 0.002
Identities = 41/154 (26%), Positives = 77/154 (50%), Gaps = 16/154 (10%)
Query: 21 LEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQDLEQL-AKEQD----KESEKQ 75
+E++ L+Q D + +L L ++ EK Q+ +I + +Q+ AK Q+ ++ +KQ
Sbjct: 94 MELRLLLQTKEDYEALIKSLKVLLAELDEKILQMEKKIANQKQIFAKMQEANNPRKLQKQ 153
Query: 76 LLLQE-----VENHKKQMLSNQASWRKANLTC---KIAIDNLEKAELLQGGDLLRQRKTT 127
+ + E V H +ML+ A RK K A DN+ + LQ LL ++KT
Sbjct: 154 IHILETRLNLVTVHFDKMLTTNAKLRKEIEDLRFEKAAYDNVYQQ--LQHC-LLMEKKTM 210
Query: 128 KESLAQTSSTITESLMGISRMMAQQVQQSEEAMQ 161
++ Q+S + + ++RM A + +Q ++ Q
Sbjct: 211 NLAIEQSSQAYEQRVEAMARMAAMKDRQKKDTSQ 244
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 39.3 bits (90), Expect = 0.003
Identities = 30/126 (23%), Positives = 65/126 (51%), Gaps = 7/126 (5%)
Query: 48 KEKF-QQLRHRIQDL--EQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKI 104
+E+F +Q + +++ L +++AK Q E+Q Q++E +++++++ R+ +
Sbjct: 2505 RERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEE 2564
Query: 105 AIDNLEKAELLQGGDLLRQRKTTKESLAQTSSTITESLMGISRMMAQQVQQSEEAMQSLV 164
+ K E LQ L +QR+ +E LA+ + + E L + + SEE S V
Sbjct: 2565 GVRR--KQEELQ--QLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQV 2620
Query: 165 TSSRTI 170
+++T+
Sbjct: 2621 AATKTL 2626
Score = 33.5 bits (75), Expect = 0.15
Identities = 30/121 (24%), Positives = 59/121 (48%), Gaps = 9/121 (7%)
Query: 60 DLEQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKA-----EL 114
+ E KE++ E+E+ L E E +++ L QA+ KA++ ++A L KA E
Sbjct: 1851 EAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLA--QLRKASDSELER 1908
Query: 115 LQG--GDLLRQRKTTKESLAQTSSTITESLMGISRMMAQQVQQSEEAMQSLVTSSRTILD 172
+G D LRQR+ +E + ++ ++ G + + + + A +L + + L+
Sbjct: 1909 QKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELE 1968
Query: 173 A 173
A
Sbjct: 1969 A 1969
Score = 33.1 bits (74), Expect = 0.20
Identities = 34/153 (22%), Positives = 68/153 (44%), Gaps = 20/153 (13%)
Query: 46 KVKEKFQQLRHRIQDLEQLAKEQDKE------------SEKQLLLQEVENHKKQMLSNQA 93
+ +E+ ++LR ++QD Q ++ + E EKQ LQ +E + Q +
Sbjct: 1491 QAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAER 1550
Query: 94 SWRKANLTCKIAID-NLEKAELLQGGDLLRQRKTTKESLAQTSSTITESLMGISRMMAQ- 151
R+A + + LE A+ +L +R + E AQ ++ E + ++++ +
Sbjct: 1551 RLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEA 1610
Query: 152 --QVQQSEEAMQSLVTSSRTI----LDANEEFK 178
+ QQ EA ++ + R + L ANE +
Sbjct: 1611 ERRAQQQAEAERAREEAERELERWQLKANEALR 1643
Score = 32.3 bits (72), Expect = 0.34
Identities = 42/178 (23%), Positives = 67/178 (37%), Gaps = 32/178 (17%)
Query: 28 QDIRDCSGPLSALTELNTKVKEKFQQLRHRIQDLEQLAKEQDKESEKQLLLQEVENHKKQ 87
Q D A+ EL + KEK QQ L QL E+ + +++ LLQE + ++
Sbjct: 2440 QSDHDAERLREAIAELERE-KEKLQQEAK----LLQLKSEEMQTVQQEQLLQETQALQQS 2494
Query: 88 MLSNQASWRKANLTCKIAIDNLEKAELLQGGDLLRQRKTTKESLAQTSSTITESLMGISR 147
LS EK LLQ + Q K E L Q + L +
Sbjct: 2495 FLS-------------------EKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQ 2535
Query: 148 MMAQQVQQS--------EEAMQSLVTSSRTILDANEEFKSMSGTIQLGRKLITKYNRR 197
QQ++Q EEA + + + EE + + + +L+ + N+R
Sbjct: 2536 RQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQR 2593
Score = 29.6 bits (65), Expect = 2.2
Identities = 26/117 (22%), Positives = 54/117 (46%), Gaps = 10/117 (8%)
Query: 49 EKFQQLRHRIQDLEQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDN 108
E+ +L+ RI+ + +DK++ ++ L +E E K Q + A L+ +A
Sbjct: 2238 EELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMK------QVAEEAARLS--VAAQE 2289
Query: 109 LEKAELLQGGDLLRQRKTTKESLAQTSSTITES--LMGISRMMAQQVQQSEEAMQSL 163
+ L DL +QR ++ L + + E+ L + ++ QQ + ++E + L
Sbjct: 2290 AARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRL 2346
Score = 27.7 bits (60), Expect = 8.5
Identities = 26/122 (21%), Positives = 57/122 (46%), Gaps = 6/122 (4%)
Query: 54 LRHRIQDLEQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAE 113
LR + Q + A+++ +E++ +E E ++ L A+ +A K A++ +E+ +
Sbjct: 1959 LRSKEQAELEAARQRQLAAEEERRRREAEERVQKSL---AAEEEAARQRKAALEEVERLK 2015
Query: 114 L-LQGGDLLRQR--KTTKESLAQTSSTITESLMGISRMMAQQVQQSEEAMQSLVTSSRTI 170
++ LR+R + + L + L + A VQQ E+ +Q + +++
Sbjct: 2016 AKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSV 2075
Query: 171 LD 172
LD
Sbjct: 2076 LD 2077
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 39.3 bits (90), Expect = 0.003
Identities = 30/126 (23%), Positives = 65/126 (51%), Gaps = 7/126 (5%)
Query: 48 KEKF-QQLRHRIQDL--EQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKI 104
+E+F +Q + +++ L +++AK Q E+Q Q++E +++++++ R+ +
Sbjct: 2509 RERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEE 2568
Query: 105 AIDNLEKAELLQGGDLLRQRKTTKESLAQTSSTITESLMGISRMMAQQVQQSEEAMQSLV 164
+ K E LQ L +QR+ +E LA+ + + E L + + SEE S V
Sbjct: 2569 GVRR--KQEELQ--QLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQV 2624
Query: 165 TSSRTI 170
+++T+
Sbjct: 2625 AATKTL 2630
Score = 33.5 bits (75), Expect = 0.15
Identities = 30/121 (24%), Positives = 59/121 (48%), Gaps = 9/121 (7%)
Query: 60 DLEQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKA-----EL 114
+ E KE++ E+E+ L E E +++ L QA+ KA++ ++A L KA E
Sbjct: 1855 EAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLA--QLRKASDSELER 1912
Query: 115 LQG--GDLLRQRKTTKESLAQTSSTITESLMGISRMMAQQVQQSEEAMQSLVTSSRTILD 172
+G D LRQR+ +E + ++ ++ G + + + + A +L + + L+
Sbjct: 1913 QKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELE 1972
Query: 173 A 173
A
Sbjct: 1973 A 1973
Score = 33.1 bits (74), Expect = 0.20
Identities = 34/153 (22%), Positives = 68/153 (44%), Gaps = 20/153 (13%)
Query: 46 KVKEKFQQLRHRIQDLEQLAKEQDKE------------SEKQLLLQEVENHKKQMLSNQA 93
+ +E+ ++LR ++QD Q ++ + E EKQ LQ +E + Q +
Sbjct: 1495 QAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAER 1554
Query: 94 SWRKANLTCKIAID-NLEKAELLQGGDLLRQRKTTKESLAQTSSTITESLMGISRMMAQ- 151
R+A + + LE A+ +L +R + E AQ ++ E + ++++ +
Sbjct: 1555 RLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEA 1614
Query: 152 --QVQQSEEAMQSLVTSSRTI----LDANEEFK 178
+ QQ EA ++ + R + L ANE +
Sbjct: 1615 ERRAQQQAEAERAREEAERELERWQLKANEALR 1647
Score = 32.3 bits (72), Expect = 0.34
Identities = 42/178 (23%), Positives = 67/178 (37%), Gaps = 32/178 (17%)
Query: 28 QDIRDCSGPLSALTELNTKVKEKFQQLRHRIQDLEQLAKEQDKESEKQLLLQEVENHKKQ 87
Q D A+ EL + KEK QQ L QL E+ + +++ LLQE + ++
Sbjct: 2444 QSDHDAERLREAIAELERE-KEKLQQEAK----LLQLKSEEMQTVQQEQLLQETQALQQS 2498
Query: 88 MLSNQASWRKANLTCKIAIDNLEKAELLQGGDLLRQRKTTKESLAQTSSTITESLMGISR 147
LS EK LLQ + Q K E L Q + L +
Sbjct: 2499 FLS-------------------EKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQ 2539
Query: 148 MMAQQVQQS--------EEAMQSLVTSSRTILDANEEFKSMSGTIQLGRKLITKYNRR 197
QQ++Q EEA + + + EE + + + +L+ + N+R
Sbjct: 2540 RQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQR 2597
Score = 29.6 bits (65), Expect = 2.2
Identities = 26/117 (22%), Positives = 54/117 (46%), Gaps = 10/117 (8%)
Query: 49 EKFQQLRHRIQDLEQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDN 108
E+ +L+ RI+ + +DK++ ++ L +E E K Q + A L+ +A
Sbjct: 2242 EELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMK------QVAEEAARLS--VAAQE 2293
Query: 109 LEKAELLQGGDLLRQRKTTKESLAQTSSTITES--LMGISRMMAQQVQQSEEAMQSL 163
+ L DL +QR ++ L + + E+ L + ++ QQ + ++E + L
Sbjct: 2294 AARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRL 2350
Score = 27.7 bits (60), Expect = 8.5
Identities = 26/122 (21%), Positives = 57/122 (46%), Gaps = 6/122 (4%)
Query: 54 LRHRIQDLEQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAE 113
LR + Q + A+++ +E++ +E E ++ L A+ +A K A++ +E+ +
Sbjct: 1963 LRSKEQAELEAARQRQLAAEEERRRREAEERVQKSL---AAEEEAARQRKAALEEVERLK 2019
Query: 114 L-LQGGDLLRQR--KTTKESLAQTSSTITESLMGISRMMAQQVQQSEEAMQSLVTSSRTI 170
++ LR+R + + L + L + A VQQ E+ +Q + +++
Sbjct: 2020 AKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSV 2079
Query: 171 LD 172
LD
Sbjct: 2080 LD 2081
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 39.3 bits (90), Expect = 0.003
Identities = 30/126 (23%), Positives = 65/126 (51%), Gaps = 7/126 (5%)
Query: 48 KEKF-QQLRHRIQDL--EQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKI 104
+E+F +Q + +++ L +++AK Q E+Q Q++E +++++++ R+ +
Sbjct: 2505 RERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEE 2564
Query: 105 AIDNLEKAELLQGGDLLRQRKTTKESLAQTSSTITESLMGISRMMAQQVQQSEEAMQSLV 164
+ K E LQ L +QR+ +E LA+ + + E L + + SEE S V
Sbjct: 2565 GVRR--KQEELQ--QLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQV 2620
Query: 165 TSSRTI 170
+++T+
Sbjct: 2621 AATKTL 2626
Score = 33.5 bits (75), Expect = 0.15
Identities = 30/121 (24%), Positives = 59/121 (48%), Gaps = 9/121 (7%)
Query: 60 DLEQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKA-----EL 114
+ E KE++ E+E+ L E E +++ L QA+ KA++ ++A L KA E
Sbjct: 1851 EAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLA--QLRKASDSELER 1908
Query: 115 LQG--GDLLRQRKTTKESLAQTSSTITESLMGISRMMAQQVQQSEEAMQSLVTSSRTILD 172
+G D LRQR+ +E + ++ ++ G + + + + A +L + + L+
Sbjct: 1909 QKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELE 1968
Query: 173 A 173
A
Sbjct: 1969 A 1969
Score = 33.1 bits (74), Expect = 0.20
Identities = 34/153 (22%), Positives = 68/153 (44%), Gaps = 20/153 (13%)
Query: 46 KVKEKFQQLRHRIQDLEQLAKEQDKE------------SEKQLLLQEVENHKKQMLSNQA 93
+ +E+ ++LR ++QD Q ++ + E EKQ LQ +E + Q +
Sbjct: 1491 QAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAER 1550
Query: 94 SWRKANLTCKIAID-NLEKAELLQGGDLLRQRKTTKESLAQTSSTITESLMGISRMMAQ- 151
R+A + + LE A+ +L +R + E AQ ++ E + ++++ +
Sbjct: 1551 RLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEA 1610
Query: 152 --QVQQSEEAMQSLVTSSRTI----LDANEEFK 178
+ QQ EA ++ + R + L ANE +
Sbjct: 1611 ERRAQQQAEAERAREEAERELERWQLKANEALR 1643
Score = 32.3 bits (72), Expect = 0.34
Identities = 42/178 (23%), Positives = 67/178 (37%), Gaps = 32/178 (17%)
Query: 28 QDIRDCSGPLSALTELNTKVKEKFQQLRHRIQDLEQLAKEQDKESEKQLLLQEVENHKKQ 87
Q D A+ EL + KEK QQ L QL E+ + +++ LLQE + ++
Sbjct: 2440 QSDHDAERLREAIAELERE-KEKLQQEAK----LLQLKSEEMQTVQQEQLLQETQALQQS 2494
Query: 88 MLSNQASWRKANLTCKIAIDNLEKAELLQGGDLLRQRKTTKESLAQTSSTITESLMGISR 147
LS EK LLQ + Q K E L Q + L +
Sbjct: 2495 FLS-------------------EKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQ 2535
Query: 148 MMAQQVQQS--------EEAMQSLVTSSRTILDANEEFKSMSGTIQLGRKLITKYNRR 197
QQ++Q EEA + + + EE + + + +L+ + N+R
Sbjct: 2536 RQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQR 2593
Score = 29.6 bits (65), Expect = 2.2
Identities = 26/117 (22%), Positives = 54/117 (46%), Gaps = 10/117 (8%)
Query: 49 EKFQQLRHRIQDLEQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDN 108
E+ +L+ RI+ + +DK++ ++ L +E E K Q + A L+ +A
Sbjct: 2238 EELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMK------QVAEEAARLS--VAAQE 2289
Query: 109 LEKAELLQGGDLLRQRKTTKESLAQTSSTITES--LMGISRMMAQQVQQSEEAMQSL 163
+ L DL +QR ++ L + + E+ L + ++ QQ + ++E + L
Sbjct: 2290 AARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRL 2346
Score = 27.7 bits (60), Expect = 8.5
Identities = 26/122 (21%), Positives = 57/122 (46%), Gaps = 6/122 (4%)
Query: 54 LRHRIQDLEQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAE 113
LR + Q + A+++ +E++ +E E ++ L A+ +A K A++ +E+ +
Sbjct: 1959 LRSKEQAELEAARQRQLAAEEERRRREAEERVQKSL---AAEEEAARQRKAALEEVERLK 2015
Query: 114 L-LQGGDLLRQR--KTTKESLAQTSSTITESLMGISRMMAQQVQQSEEAMQSLVTSSRTI 170
++ LR+R + + L + L + A VQQ E+ +Q + +++
Sbjct: 2016 AKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSV 2075
Query: 171 LD 172
LD
Sbjct: 2076 LD 2077
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 39.3 bits (90), Expect = 0.003
Identities = 30/126 (23%), Positives = 65/126 (51%), Gaps = 7/126 (5%)
Query: 48 KEKF-QQLRHRIQDL--EQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKI 104
+E+F +Q + +++ L +++AK Q E+Q Q++E +++++++ R+ +
Sbjct: 2473 RERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEE 2532
Query: 105 AIDNLEKAELLQGGDLLRQRKTTKESLAQTSSTITESLMGISRMMAQQVQQSEEAMQSLV 164
+ K E LQ L +QR+ +E LA+ + + E L + + SEE S V
Sbjct: 2533 GVRR--KQEELQ--QLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQV 2588
Query: 165 TSSRTI 170
+++T+
Sbjct: 2589 AATKTL 2594
Score = 33.5 bits (75), Expect = 0.15
Identities = 30/121 (24%), Positives = 59/121 (48%), Gaps = 9/121 (7%)
Query: 60 DLEQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKA-----EL 114
+ E KE++ E+E+ L E E +++ L QA+ KA++ ++A L KA E
Sbjct: 1819 EAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLA--QLRKASDSELER 1876
Query: 115 LQG--GDLLRQRKTTKESLAQTSSTITESLMGISRMMAQQVQQSEEAMQSLVTSSRTILD 172
+G D LRQR+ +E + ++ ++ G + + + + A +L + + L+
Sbjct: 1877 QKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELE 1936
Query: 173 A 173
A
Sbjct: 1937 A 1937
Score = 33.1 bits (74), Expect = 0.20
Identities = 34/153 (22%), Positives = 68/153 (44%), Gaps = 20/153 (13%)
Query: 46 KVKEKFQQLRHRIQDLEQLAKEQDKE------------SEKQLLLQEVENHKKQMLSNQA 93
+ +E+ ++LR ++QD Q ++ + E EKQ LQ +E + Q +
Sbjct: 1459 QAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAER 1518
Query: 94 SWRKANLTCKIAID-NLEKAELLQGGDLLRQRKTTKESLAQTSSTITESLMGISRMMAQ- 151
R+A + + LE A+ +L +R + E AQ ++ E + ++++ +
Sbjct: 1519 RLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEA 1578
Query: 152 --QVQQSEEAMQSLVTSSRTI----LDANEEFK 178
+ QQ EA ++ + R + L ANE +
Sbjct: 1579 ERRAQQQAEAERAREEAERELERWQLKANEALR 1611
Score = 32.3 bits (72), Expect = 0.34
Identities = 42/178 (23%), Positives = 67/178 (37%), Gaps = 32/178 (17%)
Query: 28 QDIRDCSGPLSALTELNTKVKEKFQQLRHRIQDLEQLAKEQDKESEKQLLLQEVENHKKQ 87
Q D A+ EL + KEK QQ L QL E+ + +++ LLQE + ++
Sbjct: 2408 QSDHDAERLREAIAELERE-KEKLQQEAK----LLQLKSEEMQTVQQEQLLQETQALQQS 2462
Query: 88 MLSNQASWRKANLTCKIAIDNLEKAELLQGGDLLRQRKTTKESLAQTSSTITESLMGISR 147
LS EK LLQ + Q K E L Q + L +
Sbjct: 2463 FLS-------------------EKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQ 2503
Query: 148 MMAQQVQQS--------EEAMQSLVTSSRTILDANEEFKSMSGTIQLGRKLITKYNRR 197
QQ++Q EEA + + + EE + + + +L+ + N+R
Sbjct: 2504 RQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQR 2561
Score = 29.6 bits (65), Expect = 2.2
Identities = 26/117 (22%), Positives = 54/117 (46%), Gaps = 10/117 (8%)
Query: 49 EKFQQLRHRIQDLEQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDN 108
E+ +L+ RI+ + +DK++ ++ L +E E K Q + A L+ +A
Sbjct: 2206 EELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMK------QVAEEAARLS--VAAQE 2257
Query: 109 LEKAELLQGGDLLRQRKTTKESLAQTSSTITES--LMGISRMMAQQVQQSEEAMQSL 163
+ L DL +QR ++ L + + E+ L + ++ QQ + ++E + L
Sbjct: 2258 AARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRL 2314
Score = 27.7 bits (60), Expect = 8.5
Identities = 26/122 (21%), Positives = 57/122 (46%), Gaps = 6/122 (4%)
Query: 54 LRHRIQDLEQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAE 113
LR + Q + A+++ +E++ +E E ++ L A+ +A K A++ +E+ +
Sbjct: 1927 LRSKEQAELEAARQRQLAAEEERRRREAEERVQKSL---AAEEEAARQRKAALEEVERLK 1983
Query: 114 L-LQGGDLLRQR--KTTKESLAQTSSTITESLMGISRMMAQQVQQSEEAMQSLVTSSRTI 170
++ LR+R + + L + L + A VQQ E+ +Q + +++
Sbjct: 1984 AKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSV 2043
Query: 171 LD 172
LD
Sbjct: 2044 LD 2045
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 39.3 bits (90), Expect = 0.003
Identities = 30/126 (23%), Positives = 65/126 (51%), Gaps = 7/126 (5%)
Query: 48 KEKF-QQLRHRIQDL--EQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKI 104
+E+F +Q + +++ L +++AK Q E+Q Q++E +++++++ R+ +
Sbjct: 2642 RERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEE 2701
Query: 105 AIDNLEKAELLQGGDLLRQRKTTKESLAQTSSTITESLMGISRMMAQQVQQSEEAMQSLV 164
+ K E LQ L +QR+ +E LA+ + + E L + + SEE S V
Sbjct: 2702 GVRR--KQEELQ--QLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQV 2757
Query: 165 TSSRTI 170
+++T+
Sbjct: 2758 AATKTL 2763
Score = 33.5 bits (75), Expect = 0.15
Identities = 30/121 (24%), Positives = 59/121 (48%), Gaps = 9/121 (7%)
Query: 60 DLEQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKA-----EL 114
+ E KE++ E+E+ L E E +++ L QA+ KA++ ++A L KA E
Sbjct: 1988 EAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLA--QLRKASDSELER 2045
Query: 115 LQG--GDLLRQRKTTKESLAQTSSTITESLMGISRMMAQQVQQSEEAMQSLVTSSRTILD 172
+G D LRQR+ +E + ++ ++ G + + + + A +L + + L+
Sbjct: 2046 QKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELE 2105
Query: 173 A 173
A
Sbjct: 2106 A 2106
Score = 33.1 bits (74), Expect = 0.20
Identities = 34/153 (22%), Positives = 68/153 (44%), Gaps = 20/153 (13%)
Query: 46 KVKEKFQQLRHRIQDLEQLAKEQDKE------------SEKQLLLQEVENHKKQMLSNQA 93
+ +E+ ++LR ++QD Q ++ + E EKQ LQ +E + Q +
Sbjct: 1628 QAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAER 1687
Query: 94 SWRKANLTCKIAID-NLEKAELLQGGDLLRQRKTTKESLAQTSSTITESLMGISRMMAQ- 151
R+A + + LE A+ +L +R + E AQ ++ E + ++++ +
Sbjct: 1688 RLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEA 1747
Query: 152 --QVQQSEEAMQSLVTSSRTI----LDANEEFK 178
+ QQ EA ++ + R + L ANE +
Sbjct: 1748 ERRAQQQAEAERAREEAERELERWQLKANEALR 1780
Score = 32.3 bits (72), Expect = 0.34
Identities = 42/178 (23%), Positives = 67/178 (37%), Gaps = 32/178 (17%)
Query: 28 QDIRDCSGPLSALTELNTKVKEKFQQLRHRIQDLEQLAKEQDKESEKQLLLQEVENHKKQ 87
Q D A+ EL + KEK QQ L QL E+ + +++ LLQE + ++
Sbjct: 2577 QSDHDAERLREAIAELERE-KEKLQQEAK----LLQLKSEEMQTVQQEQLLQETQALQQS 2631
Query: 88 MLSNQASWRKANLTCKIAIDNLEKAELLQGGDLLRQRKTTKESLAQTSSTITESLMGISR 147
LS EK LLQ + Q K E L Q + L +
Sbjct: 2632 FLS-------------------EKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQ 2672
Query: 148 MMAQQVQQS--------EEAMQSLVTSSRTILDANEEFKSMSGTIQLGRKLITKYNRR 197
QQ++Q EEA + + + EE + + + +L+ + N+R
Sbjct: 2673 RQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQR 2730
Score = 29.6 bits (65), Expect = 2.2
Identities = 26/117 (22%), Positives = 54/117 (46%), Gaps = 10/117 (8%)
Query: 49 EKFQQLRHRIQDLEQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDN 108
E+ +L+ RI+ + +DK++ ++ L +E E K Q + A L+ +A
Sbjct: 2375 EELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMK------QVAEEAARLS--VAAQE 2426
Query: 109 LEKAELLQGGDLLRQRKTTKESLAQTSSTITES--LMGISRMMAQQVQQSEEAMQSL 163
+ L DL +QR ++ L + + E+ L + ++ QQ + ++E + L
Sbjct: 2427 AARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRL 2483
Score = 27.7 bits (60), Expect = 8.5
Identities = 26/122 (21%), Positives = 57/122 (46%), Gaps = 6/122 (4%)
Query: 54 LRHRIQDLEQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAE 113
LR + Q + A+++ +E++ +E E ++ L A+ +A K A++ +E+ +
Sbjct: 2096 LRSKEQAELEAARQRQLAAEEERRRREAEERVQKSL---AAEEEAARQRKAALEEVERLK 2152
Query: 114 L-LQGGDLLRQR--KTTKESLAQTSSTITESLMGISRMMAQQVQQSEEAMQSLVTSSRTI 170
++ LR+R + + L + L + A VQQ E+ +Q + +++
Sbjct: 2153 AKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSV 2212
Query: 171 LD 172
LD
Sbjct: 2213 LD 2214
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 39.3 bits (90), Expect = 0.003
Identities = 30/126 (23%), Positives = 65/126 (51%), Gaps = 7/126 (5%)
Query: 48 KEKF-QQLRHRIQDL--EQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKI 104
+E+F +Q + +++ L +++AK Q E+Q Q++E +++++++ R+ +
Sbjct: 2483 RERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEE 2542
Query: 105 AIDNLEKAELLQGGDLLRQRKTTKESLAQTSSTITESLMGISRMMAQQVQQSEEAMQSLV 164
+ K E LQ L +QR+ +E LA+ + + E L + + SEE S V
Sbjct: 2543 GVRR--KQEELQ--QLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQV 2598
Query: 165 TSSRTI 170
+++T+
Sbjct: 2599 AATKTL 2604
Score = 33.5 bits (75), Expect = 0.15
Identities = 30/121 (24%), Positives = 59/121 (48%), Gaps = 9/121 (7%)
Query: 60 DLEQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKA-----EL 114
+ E KE++ E+E+ L E E +++ L QA+ KA++ ++A L KA E
Sbjct: 1829 EAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLA--QLRKASDSELER 1886
Query: 115 LQG--GDLLRQRKTTKESLAQTSSTITESLMGISRMMAQQVQQSEEAMQSLVTSSRTILD 172
+G D LRQR+ +E + ++ ++ G + + + + A +L + + L+
Sbjct: 1887 QKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELE 1946
Query: 173 A 173
A
Sbjct: 1947 A 1947
Score = 33.1 bits (74), Expect = 0.20
Identities = 34/153 (22%), Positives = 68/153 (44%), Gaps = 20/153 (13%)
Query: 46 KVKEKFQQLRHRIQDLEQLAKEQDKE------------SEKQLLLQEVENHKKQMLSNQA 93
+ +E+ ++LR ++QD Q ++ + E EKQ LQ +E + Q +
Sbjct: 1469 QAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAER 1528
Query: 94 SWRKANLTCKIAID-NLEKAELLQGGDLLRQRKTTKESLAQTSSTITESLMGISRMMAQ- 151
R+A + + LE A+ +L +R + E AQ ++ E + ++++ +
Sbjct: 1529 RLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEA 1588
Query: 152 --QVQQSEEAMQSLVTSSRTI----LDANEEFK 178
+ QQ EA ++ + R + L ANE +
Sbjct: 1589 ERRAQQQAEAERAREEAERELERWQLKANEALR 1621
Score = 32.3 bits (72), Expect = 0.34
Identities = 42/178 (23%), Positives = 67/178 (37%), Gaps = 32/178 (17%)
Query: 28 QDIRDCSGPLSALTELNTKVKEKFQQLRHRIQDLEQLAKEQDKESEKQLLLQEVENHKKQ 87
Q D A+ EL + KEK QQ L QL E+ + +++ LLQE + ++
Sbjct: 2418 QSDHDAERLREAIAELERE-KEKLQQEAK----LLQLKSEEMQTVQQEQLLQETQALQQS 2472
Query: 88 MLSNQASWRKANLTCKIAIDNLEKAELLQGGDLLRQRKTTKESLAQTSSTITESLMGISR 147
LS EK LLQ + Q K E L Q + L +
Sbjct: 2473 FLS-------------------EKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQ 2513
Query: 148 MMAQQVQQS--------EEAMQSLVTSSRTILDANEEFKSMSGTIQLGRKLITKYNRR 197
QQ++Q EEA + + + EE + + + +L+ + N+R
Sbjct: 2514 RQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQR 2571
Score = 29.6 bits (65), Expect = 2.2
Identities = 26/117 (22%), Positives = 54/117 (46%), Gaps = 10/117 (8%)
Query: 49 EKFQQLRHRIQDLEQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDN 108
E+ +L+ RI+ + +DK++ ++ L +E E K Q + A L+ +A
Sbjct: 2216 EELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMK------QVAEEAARLS--VAAQE 2267
Query: 109 LEKAELLQGGDLLRQRKTTKESLAQTSSTITES--LMGISRMMAQQVQQSEEAMQSL 163
+ L DL +QR ++ L + + E+ L + ++ QQ + ++E + L
Sbjct: 2268 AARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRL 2324
Score = 27.7 bits (60), Expect = 8.5
Identities = 26/122 (21%), Positives = 57/122 (46%), Gaps = 6/122 (4%)
Query: 54 LRHRIQDLEQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAE 113
LR + Q + A+++ +E++ +E E ++ L A+ +A K A++ +E+ +
Sbjct: 1937 LRSKEQAELEAARQRQLAAEEERRRREAEERVQKSL---AAEEEAARQRKAALEEVERLK 1993
Query: 114 L-LQGGDLLRQR--KTTKESLAQTSSTITESLMGISRMMAQQVQQSEEAMQSLVTSSRTI 170
++ LR+R + + L + L + A VQQ E+ +Q + +++
Sbjct: 1994 AKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSV 2053
Query: 171 LD 172
LD
Sbjct: 2054 LD 2055
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 39.3 bits (90), Expect = 0.003
Identities = 30/126 (23%), Positives = 65/126 (51%), Gaps = 7/126 (5%)
Query: 48 KEKF-QQLRHRIQDL--EQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKI 104
+E+F +Q + +++ L +++AK Q E+Q Q++E +++++++ R+ +
Sbjct: 2491 RERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEE 2550
Query: 105 AIDNLEKAELLQGGDLLRQRKTTKESLAQTSSTITESLMGISRMMAQQVQQSEEAMQSLV 164
+ K E LQ L +QR+ +E LA+ + + E L + + SEE S V
Sbjct: 2551 GVRR--KQEELQ--QLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQV 2606
Query: 165 TSSRTI 170
+++T+
Sbjct: 2607 AATKTL 2612
Score = 33.5 bits (75), Expect = 0.15
Identities = 30/121 (24%), Positives = 59/121 (48%), Gaps = 9/121 (7%)
Query: 60 DLEQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKA-----EL 114
+ E KE++ E+E+ L E E +++ L QA+ KA++ ++A L KA E
Sbjct: 1837 EAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLA--QLRKASDSELER 1894
Query: 115 LQG--GDLLRQRKTTKESLAQTSSTITESLMGISRMMAQQVQQSEEAMQSLVTSSRTILD 172
+G D LRQR+ +E + ++ ++ G + + + + A +L + + L+
Sbjct: 1895 QKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELE 1954
Query: 173 A 173
A
Sbjct: 1955 A 1955
Score = 33.1 bits (74), Expect = 0.20
Identities = 34/153 (22%), Positives = 68/153 (44%), Gaps = 20/153 (13%)
Query: 46 KVKEKFQQLRHRIQDLEQLAKEQDKE------------SEKQLLLQEVENHKKQMLSNQA 93
+ +E+ ++LR ++QD Q ++ + E EKQ LQ +E + Q +
Sbjct: 1477 QAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAER 1536
Query: 94 SWRKANLTCKIAID-NLEKAELLQGGDLLRQRKTTKESLAQTSSTITESLMGISRMMAQ- 151
R+A + + LE A+ +L +R + E AQ ++ E + ++++ +
Sbjct: 1537 RLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEA 1596
Query: 152 --QVQQSEEAMQSLVTSSRTI----LDANEEFK 178
+ QQ EA ++ + R + L ANE +
Sbjct: 1597 ERRAQQQAEAERAREEAERELERWQLKANEALR 1629
Score = 32.3 bits (72), Expect = 0.34
Identities = 42/178 (23%), Positives = 67/178 (37%), Gaps = 32/178 (17%)
Query: 28 QDIRDCSGPLSALTELNTKVKEKFQQLRHRIQDLEQLAKEQDKESEKQLLLQEVENHKKQ 87
Q D A+ EL + KEK QQ L QL E+ + +++ LLQE + ++
Sbjct: 2426 QSDHDAERLREAIAELERE-KEKLQQEAK----LLQLKSEEMQTVQQEQLLQETQALQQS 2480
Query: 88 MLSNQASWRKANLTCKIAIDNLEKAELLQGGDLLRQRKTTKESLAQTSSTITESLMGISR 147
LS EK LLQ + Q K E L Q + L +
Sbjct: 2481 FLS-------------------EKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQ 2521
Query: 148 MMAQQVQQS--------EEAMQSLVTSSRTILDANEEFKSMSGTIQLGRKLITKYNRR 197
QQ++Q EEA + + + EE + + + +L+ + N+R
Sbjct: 2522 RQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQR 2579
Score = 29.6 bits (65), Expect = 2.2
Identities = 26/117 (22%), Positives = 54/117 (46%), Gaps = 10/117 (8%)
Query: 49 EKFQQLRHRIQDLEQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDN 108
E+ +L+ RI+ + +DK++ ++ L +E E K Q + A L+ +A
Sbjct: 2224 EELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMK------QVAEEAARLS--VAAQE 2275
Query: 109 LEKAELLQGGDLLRQRKTTKESLAQTSSTITES--LMGISRMMAQQVQQSEEAMQSL 163
+ L DL +QR ++ L + + E+ L + ++ QQ + ++E + L
Sbjct: 2276 AARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRL 2332
Score = 27.7 bits (60), Expect = 8.5
Identities = 26/122 (21%), Positives = 57/122 (46%), Gaps = 6/122 (4%)
Query: 54 LRHRIQDLEQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAE 113
LR + Q + A+++ +E++ +E E ++ L A+ +A K A++ +E+ +
Sbjct: 1945 LRSKEQAELEAARQRQLAAEEERRRREAEERVQKSL---AAEEEAARQRKAALEEVERLK 2001
Query: 114 L-LQGGDLLRQR--KTTKESLAQTSSTITESLMGISRMMAQQVQQSEEAMQSLVTSSRTI 170
++ LR+R + + L + L + A VQQ E+ +Q + +++
Sbjct: 2002 AKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSV 2061
Query: 171 LD 172
LD
Sbjct: 2062 LD 2063
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 39.3 bits (90), Expect = 0.003
Identities = 30/126 (23%), Positives = 65/126 (51%), Gaps = 7/126 (5%)
Query: 48 KEKF-QQLRHRIQDL--EQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKI 104
+E+F +Q + +++ L +++AK Q E+Q Q++E +++++++ R+ +
Sbjct: 2532 RERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEE 2591
Query: 105 AIDNLEKAELLQGGDLLRQRKTTKESLAQTSSTITESLMGISRMMAQQVQQSEEAMQSLV 164
+ K E LQ L +QR+ +E LA+ + + E L + + SEE S V
Sbjct: 2592 GVRR--KQEELQ--QLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQV 2647
Query: 165 TSSRTI 170
+++T+
Sbjct: 2648 AATKTL 2653
Score = 33.5 bits (75), Expect = 0.15
Identities = 30/121 (24%), Positives = 59/121 (48%), Gaps = 9/121 (7%)
Query: 60 DLEQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKA-----EL 114
+ E KE++ E+E+ L E E +++ L QA+ KA++ ++A L KA E
Sbjct: 1878 EAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLA--QLRKASDSELER 1935
Query: 115 LQG--GDLLRQRKTTKESLAQTSSTITESLMGISRMMAQQVQQSEEAMQSLVTSSRTILD 172
+G D LRQR+ +E + ++ ++ G + + + + A +L + + L+
Sbjct: 1936 QKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELE 1995
Query: 173 A 173
A
Sbjct: 1996 A 1996
Score = 33.1 bits (74), Expect = 0.20
Identities = 34/153 (22%), Positives = 68/153 (44%), Gaps = 20/153 (13%)
Query: 46 KVKEKFQQLRHRIQDLEQLAKEQDKE------------SEKQLLLQEVENHKKQMLSNQA 93
+ +E+ ++LR ++QD Q ++ + E EKQ LQ +E + Q +
Sbjct: 1518 QAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAER 1577
Query: 94 SWRKANLTCKIAID-NLEKAELLQGGDLLRQRKTTKESLAQTSSTITESLMGISRMMAQ- 151
R+A + + LE A+ +L +R + E AQ ++ E + ++++ +
Sbjct: 1578 RLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEA 1637
Query: 152 --QVQQSEEAMQSLVTSSRTI----LDANEEFK 178
+ QQ EA ++ + R + L ANE +
Sbjct: 1638 ERRAQQQAEAERAREEAERELERWQLKANEALR 1670
Score = 32.3 bits (72), Expect = 0.34
Identities = 42/178 (23%), Positives = 67/178 (37%), Gaps = 32/178 (17%)
Query: 28 QDIRDCSGPLSALTELNTKVKEKFQQLRHRIQDLEQLAKEQDKESEKQLLLQEVENHKKQ 87
Q D A+ EL + KEK QQ L QL E+ + +++ LLQE + ++
Sbjct: 2467 QSDHDAERLREAIAELERE-KEKLQQEAK----LLQLKSEEMQTVQQEQLLQETQALQQS 2521
Query: 88 MLSNQASWRKANLTCKIAIDNLEKAELLQGGDLLRQRKTTKESLAQTSSTITESLMGISR 147
LS EK LLQ + Q K E L Q + L +
Sbjct: 2522 FLS-------------------EKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQ 2562
Query: 148 MMAQQVQQS--------EEAMQSLVTSSRTILDANEEFKSMSGTIQLGRKLITKYNRR 197
QQ++Q EEA + + + EE + + + +L+ + N+R
Sbjct: 2563 RQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQR 2620
Score = 29.6 bits (65), Expect = 2.2
Identities = 26/117 (22%), Positives = 54/117 (46%), Gaps = 10/117 (8%)
Query: 49 EKFQQLRHRIQDLEQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDN 108
E+ +L+ RI+ + +DK++ ++ L +E E K Q + A L+ +A
Sbjct: 2265 EELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMK------QVAEEAARLS--VAAQE 2316
Query: 109 LEKAELLQGGDLLRQRKTTKESLAQTSSTITES--LMGISRMMAQQVQQSEEAMQSL 163
+ L DL +QR ++ L + + E+ L + ++ QQ + ++E + L
Sbjct: 2317 AARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRL 2373
Score = 27.7 bits (60), Expect = 8.5
Identities = 26/122 (21%), Positives = 57/122 (46%), Gaps = 6/122 (4%)
Query: 54 LRHRIQDLEQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAE 113
LR + Q + A+++ +E++ +E E ++ L A+ +A K A++ +E+ +
Sbjct: 1986 LRSKEQAELEAARQRQLAAEEERRRREAEERVQKSL---AAEEEAARQRKAALEEVERLK 2042
Query: 114 L-LQGGDLLRQR--KTTKESLAQTSSTITESLMGISRMMAQQVQQSEEAMQSLVTSSRTI 170
++ LR+R + + L + L + A VQQ E+ +Q + +++
Sbjct: 2043 AKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSV 2102
Query: 171 LD 172
LD
Sbjct: 2103 LD 2104
>gi|124249396 coiled-coil domain containing 30 [Homo sapiens]
Length = 783
Score = 38.9 bits (89), Expect = 0.004
Identities = 47/222 (21%), Positives = 93/222 (41%), Gaps = 38/222 (17%)
Query: 12 CNQEIVKFDLEVKALIQDIRDCSGPLSALTELNTKV---KEKFQQLRHRI---------- 58
C Q+I + +LEV Q I+ + L + +KV +EK L+ ++
Sbjct: 314 CQQKIKELELEVLKHTQSIKSQNNLQEKLVQEKSKVADAEEKILDLQRKLEHAHKVCLTD 373
Query: 59 ------QDLEQLAKE------------QDKESEKQLLLQEVENHKKQMLSNQASWRKANL 100
Q LE+ KE Q+++ +++LL Q V+ +Q+ + Q +
Sbjct: 374 TCISEKQQLEEKIKEATQNEAKVKQQYQEEQQKRKLLYQNVDELHRQVRTLQDKENLLEM 433
Query: 101 TCKIAIDNLEKAELLQGGDLLRQRKTTKESLAQTSSTITESLMGISRMMAQQVQQSEEAM 160
TC + +++ + Q LL+Q + K + + E +S++ ++ EE +
Sbjct: 434 TC-----SQQQSRIQQQEALLKQLENEKRKYDEHVKSNQELSEKLSKLQQEKEALREEYL 488
Query: 161 QSLVTSSRTILDANEEFKSMSGTIQLGRKLITKYNRRELTDK 202
+ L + + + NE+ +Q + +T N EL DK
Sbjct: 489 RLLKLLNVHVRNYNEKHHQQKVKLQKVKYRLT--NEVELRDK 528
>gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]
Length = 1780
Score = 38.9 bits (89), Expect = 0.004
Identities = 38/164 (23%), Positives = 73/164 (44%), Gaps = 7/164 (4%)
Query: 16 IVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQDLEQLAKEQDKESEKQ 75
I+K + +K + ++D L K+KE+ QL + +QD++ L Q KE E++
Sbjct: 1154 ILKLERNLKEFQEHLQDSVKNTKDLNVKELKLKEEITQLTNNLQDMKHLL--QLKEEEEE 1211
Query: 76 LLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDLLRQRKTTKESLAQTS 135
QE E K+++ ++ A R NL + + A+L + L +K K+ + S
Sbjct: 1212 TNRQETEKLKEELSASSA--RTQNLKADLQRKEEDYADLKE--KLTDAKKQIKQVQKEVS 1267
Query: 136 STITESLMGISRMMAQQVQQSEEAMQSLVTSSRTILDANEEFKS 179
E + + + + ++ + Q L RTI E+ +
Sbjct: 1268 VMRDEDKL-LRIKINELEKKKNQCSQELDMKQRTIQQLKEQLNN 1310
Score = 29.6 bits (65), Expect = 2.2
Identities = 37/182 (20%), Positives = 72/182 (39%), Gaps = 14/182 (7%)
Query: 17 VKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQDLEQLAKEQDKESEKQL 76
V D++++ +++ R S +T K+KE L + + AK + EK+
Sbjct: 1093 VTLDVQIQHVVEGKRALSELTQGVTCYKAKIKELETILETQKVECSHSAKLEQDILEKES 1152
Query: 77 L-------LQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDLLRQRKTTKE 129
+ L+E + H + + N L K I L L LL+ ++ +E
Sbjct: 1153 IILKLERNLKEFQEHLQDSVKNTKDLNVKELKLKEEITQLTN-NLQDMKHLLQLKEEEEE 1211
Query: 130 SLAQTSSTITESLMGIS---RMMAQQVQQSEEAMQSLVTSSRTILDANEEFKSMSGTIQL 186
+ Q + + E L S + + +Q+ EE L + DA ++ K + + +
Sbjct: 1212 TNRQETEKLKEELSASSARTQNLKADLQRKEEDYADL---KEKLTDAKKQIKQVQKEVSV 1268
Query: 187 GR 188
R
Sbjct: 1269 MR 1270
>gi|48762942 huntingtin interacting protein-1-related [Homo sapiens]
Length = 1068
Score = 38.5 bits (88), Expect = 0.005
Identities = 46/203 (22%), Positives = 96/203 (47%), Gaps = 25/203 (12%)
Query: 20 DLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQDLEQLAKEQDKESEK----- 74
DL++++L +++ S L ++ + + QL+ ++ LE +EQ K+ +K
Sbjct: 353 DLQIESLKREVEMLR---SELEKIKLEAQRYIAQLKSQVNALEGELEEQRKQKQKALVDN 409
Query: 75 --------QLLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLEK--AELLQ-GGDLLRQ 123
QL ++E + Q L +A RKA+ T + + L++ +EL+ +LLR+
Sbjct: 410 EQLRHELAQLRAAQLEGERSQGLREEAE-RKASAT-EARYNKLKEKHSELVHVHAELLRK 467
Query: 124 RKTTKESLAQTSSTITESLMGISRMMAQQVQQ-SEEAMQSLVTSSRTILDANEEFKSMSG 182
T + L T + E + + +A QV+Q E+ L S + E ++ +G
Sbjct: 468 NADTAKQLTVTQQS-QEEVARVKEQLAFQVEQVKRESELKLEEKSDQLEKLKRELEAKAG 526
Query: 183 TIQLGRKLI--TKYNRRELTDKL 203
+ ++ + T+ ++ EL+ +L
Sbjct: 527 ELARAQEALSHTEQSKSELSSRL 549
>gi|239750456 PREDICTED: similar to KIAA0655 protein [Homo sapiens]
Length = 1048
Score = 38.5 bits (88), Expect = 0.005
Identities = 46/203 (22%), Positives = 96/203 (47%), Gaps = 25/203 (12%)
Query: 20 DLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQDLEQLAKEQDKESEK----- 74
DL++++L +++ S L ++ + + QL+ ++ LE +EQ K+ +K
Sbjct: 333 DLQIESLKREVEMLR---SELEKIKLEAQRYIAQLKSQVNALEGELEEQRKQKQKALVDN 389
Query: 75 --------QLLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLEK--AELLQ-GGDLLRQ 123
QL ++E + Q L +A RKA+ T + + L++ +EL+ +LLR+
Sbjct: 390 EQLRHELAQLRAAQLEGERSQGLREEAE-RKASAT-EARYNKLKEKHSELVHVHAELLRK 447
Query: 124 RKTTKESLAQTSSTITESLMGISRMMAQQVQQ-SEEAMQSLVTSSRTILDANEEFKSMSG 182
T + L T + E + + +A QV+Q E+ L S + E ++ +G
Sbjct: 448 NADTAKQLTVTQQS-QEEVARVKEQLAFQVEQVKRESELKLEEKSDQLEKLKRELEAKAG 506
Query: 183 TIQLGRKLI--TKYNRRELTDKL 203
+ ++ + T+ ++ EL+ +L
Sbjct: 507 ELARAQEALSHTEQSKSELSSRL 529
>gi|50658065 SMC4 structural maintenance of chromosomes 4-like 1
[Homo sapiens]
Length = 1288
Score = 38.5 bits (88), Expect = 0.005
Identities = 39/184 (21%), Positives = 85/184 (46%), Gaps = 22/184 (11%)
Query: 22 EVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQDLEQLAKEQDKESEKQLLLQEV 81
E+KA +D++D L+ +T+ + KEKF QL ++D++ K + S+ + L +++
Sbjct: 361 EMKAKNKDVKDTEKKLNKITKFIEENKEKFTQL--DLEDVQVREKLKHATSKAKKLEKQL 418
Query: 82 ENHKKQMLSNQASWRKAN------LTCKIAIDNLEKAELLQGGDLLRQRKTTKESLAQTS 135
+ K+++ ++ K+N T A++ ++ E + +++ K + L +
Sbjct: 419 QKDKEKVEEFKSIPAKSNNIINETTTRNNALEKEKEKEEKKLKEVMDSLKQETQGLQKEK 478
Query: 136 STITESLMGISRMMAQ-----QVQQSE---------EAMQSLVTSSRTILDANEEFKSMS 181
+ + LMG S+ + + V QSE A+ L + ++ A+E K
Sbjct: 479 ESREKELMGFSKSVNEARSKMDVAQSELDIYLSRHNTAVSQLTKAKEALIAASETLKERK 538
Query: 182 GTIQ 185
I+
Sbjct: 539 AAIR 542
Score = 28.9 bits (63), Expect = 3.8
Identities = 19/89 (21%), Positives = 45/89 (50%), Gaps = 1/89 (1%)
Query: 6 DVHVRICNQEIVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQDLEQLA 65
D+++ N + + +ALI +A+ ++ K+ + Q+L+ + ++L++L
Sbjct: 507 DIYLSRHNTAVSQLTKAKEALIAASETLKERKAAIRDIEGKLPQTEQELKEKEKELQKLT 566
Query: 66 KEQDK-ESEKQLLLQEVENHKKQMLSNQA 93
+E+ +S L Q+VE K + N++
Sbjct: 567 QEETNFKSLVHDLFQKVEEAKSSLAMNRS 595
>gi|50658063 SMC4 structural maintenance of chromosomes 4-like 1
[Homo sapiens]
Length = 1288
Score = 38.5 bits (88), Expect = 0.005
Identities = 39/184 (21%), Positives = 85/184 (46%), Gaps = 22/184 (11%)
Query: 22 EVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQDLEQLAKEQDKESEKQLLLQEV 81
E+KA +D++D L+ +T+ + KEKF QL ++D++ K + S+ + L +++
Sbjct: 361 EMKAKNKDVKDTEKKLNKITKFIEENKEKFTQL--DLEDVQVREKLKHATSKAKKLEKQL 418
Query: 82 ENHKKQMLSNQASWRKAN------LTCKIAIDNLEKAELLQGGDLLRQRKTTKESLAQTS 135
+ K+++ ++ K+N T A++ ++ E + +++ K + L +
Sbjct: 419 QKDKEKVEEFKSIPAKSNNIINETTTRNNALEKEKEKEEKKLKEVMDSLKQETQGLQKEK 478
Query: 136 STITESLMGISRMMAQ-----QVQQSE---------EAMQSLVTSSRTILDANEEFKSMS 181
+ + LMG S+ + + V QSE A+ L + ++ A+E K
Sbjct: 479 ESREKELMGFSKSVNEARSKMDVAQSELDIYLSRHNTAVSQLTKAKEALIAASETLKERK 538
Query: 182 GTIQ 185
I+
Sbjct: 539 AAIR 542
Score = 28.9 bits (63), Expect = 3.8
Identities = 19/89 (21%), Positives = 45/89 (50%), Gaps = 1/89 (1%)
Query: 6 DVHVRICNQEIVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQDLEQLA 65
D+++ N + + +ALI +A+ ++ K+ + Q+L+ + ++L++L
Sbjct: 507 DIYLSRHNTAVSQLTKAKEALIAASETLKERKAAIRDIEGKLPQTEQELKEKEKELQKLT 566
Query: 66 KEQDK-ESEKQLLLQEVENHKKQMLSNQA 93
+E+ +S L Q+VE K + N++
Sbjct: 567 QEETNFKSLVHDLFQKVEEAKSSLAMNRS 595
>gi|31982906 cingulin-like 1 [Homo sapiens]
Length = 1302
Score = 38.1 bits (87), Expect = 0.006
Identities = 45/196 (22%), Positives = 94/196 (47%), Gaps = 20/196 (10%)
Query: 8 HVRICNQEIVK-FDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQDLEQLAK 66
H++ +VK + +V L ++ + L+E ++ +E+ +QLR+ + L++ A
Sbjct: 1054 HLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERISRSREQMEQLRNEL--LQERAA 1111
Query: 67 EQDKESEKQLLLQEVENHKKQMLSNQASWRKAN------LTCKIAI--DNLEKAELLQGG 118
QD E +K L ++ ++ K +++ + S+R + + +IA D LE E +
Sbjct: 1112 RQDLECDKISLERQNKDLKSRIIHLEGSYRSSKEGLVVQMEARIAELEDRLESEERDRAN 1171
Query: 119 DLLRQRKT---TKESLAQTSS---TITESLMGIS---RMMAQQVQQSEEAMQSLVTSSRT 169
L R+ KE + Q ++T+ +S + M +QV+++EE + L +S +
Sbjct: 1172 LQLSNRRLERKVKELVMQVDDEHLSLTDQKDQLSLRLKAMKRQVEEAEEEIDRLESSKKK 1231
Query: 170 ILDANEEFKSMSGTIQ 185
+ EE M+ +Q
Sbjct: 1232 LQRELEEQMDMNEHLQ 1247
>gi|110347443 TATA element modulatory factor 1 [Homo sapiens]
Length = 1093
Score = 37.7 bits (86), Expect = 0.008
Identities = 28/103 (27%), Positives = 48/103 (46%), Gaps = 12/103 (11%)
Query: 39 ALTELNTKVKEKFQQLRHRIQDLEQLAKEQDKESEK---------QLLLQEVENHKKQML 89
AL K LRH I +L+Q +E + +++ + LL+++EN + +
Sbjct: 724 ALQRTEQAAARKEDYLRHEIGELQQRLQEAENRNQELSQSVSSTTRPLLRQIENLQATLG 783
Query: 90 SNQASWRKANLTCKIAIDNLEKAELLQGGDLLRQRKTTKESLA 132
S +SW K K D L +++ L + R+R T+E LA
Sbjct: 784 SQTSSWEKLE---KNLSDRLGESQTLLAAAVERERAATEELLA 823
Score = 32.3 bits (72), Expect = 0.34
Identities = 33/146 (22%), Positives = 68/146 (46%), Gaps = 14/146 (9%)
Query: 40 LTELNTKVKEKFQQLRH--RIQDLEQLAKEQDKESEKQL--LLQEVENHKKQMLSNQASW 95
+ +LN KVKE ++L+H ++ D ++ ++Q +E+ K+L +++ E ++ +
Sbjct: 590 VAKLNKKVKELEEELQHLKQVLDGKEEVEKQHRENIKKLNSMVERQEKDLGRLQVDMDEL 649
Query: 96 RKANLTCKIAIDNLEKAELLQGGDLLRQRKTTKESLAQTSS-----TITESLMGISRMMA 150
+ N + + A+D+ K EL L + K+S AQ ++ E L
Sbjct: 650 EEKNRSIQAALDSAYK-ELTD----LHKANAAKDSEAQEAALSREMKAKEELSAALEKAQ 704
Query: 151 QQVQQSEEAMQSLVTSSRTILDANEE 176
++ +Q +E + V R L E+
Sbjct: 705 EEARQQQETLAIQVGDLRLALQRTEQ 730
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.130 0.342
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,582,080
Number of Sequences: 37866
Number of extensions: 240189
Number of successful extensions: 3060
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 85
Number of HSP's successfully gapped in prelim test: 340
Number of HSP's that attempted gapping in prelim test: 2298
Number of HSP's gapped (non-prelim): 1039
length of query: 228
length of database: 18,247,518
effective HSP length: 99
effective length of query: 129
effective length of database: 14,498,784
effective search space: 1870343136
effective search space used: 1870343136
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.