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Search of human proteins with 153792140
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|153792140 PRAME family member 14 [Homo sapiens]
(426 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|153792140 PRAME family member 14 [Homo sapiens] 871 0.0
gi|66954681 PRAME family member 13 [Homo sapiens] 844 0.0
gi|12738831 PRAME family member 1 [Homo sapiens] 818 0.0
gi|12738834 PRAME family member 2 [Homo sapiens] 777 0.0
gi|239741051 PREDICTED: similar to PRAME family member 10 [Homo ... 526 e-149
gi|239741055 PREDICTED: similar to PRAME family member 10 [Homo ... 526 e-149
gi|157426839 PRAME family member 17 [Homo sapiens] 516 e-146
gi|113865933 PRAME family member 16 [Homo sapiens] 514 e-146
gi|194018546 PRAME family member 10 [Homo sapiens] 508 e-144
gi|154800493 PRAME family member 22 [Homo sapiens] 486 e-137
gi|194306635 PRAME family member 19 [Homo sapiens] 486 e-137
gi|153791443 PRAME family member 18 [Homo sapiens] 482 e-136
gi|194306638 PRAME family member 3 [Homo sapiens] 480 e-136
gi|239741047 PREDICTED: PRAME family member 25-like [Homo sapiens] 424 e-118
gi|124249372 PRAME family member 12 [Homo sapiens] 412 e-115
gi|239741053 PREDICTED: similar to Putative PRAME family member ... 395 e-110
gi|59676587 PRAME family member 8 [Homo sapiens] 395 e-110
gi|59676593 PRAME family member 7 [Homo sapiens] 392 e-109
gi|153792112 PRAME family member 20 [Homo sapiens] 385 e-107
gi|153945800 PRAME family member 21 [Homo sapiens] 385 e-107
gi|61696142 PRAME family member 5 [Homo sapiens] 364 e-101
gi|58219004 PRAME family member 6 [Homo sapiens] 363 e-100
gi|148356236 PRAME family member 15 [Homo sapiens] 363 e-100
gi|61102721 PRAME family member 9 [Homo sapiens] 363 e-100
gi|239741045 PREDICTED: PRAME family member 23 [Homo sapiens] 361 e-100
gi|239741043 PREDICTED: PRAME family member 11 [Homo sapiens] 356 2e-98
gi|59958373 PRAME family member 4 [Homo sapiens] 353 1e-97
gi|46249373 preferentially expressed antigen in melanoma [Homo s... 311 6e-85
gi|46249371 preferentially expressed antigen in melanoma [Homo s... 311 6e-85
gi|46249369 preferentially expressed antigen in melanoma [Homo s... 311 6e-85
>gi|153792140 PRAME family member 14 [Homo sapiens]
Length = 426
Score = 871 bits (2251), Expect = 0.0
Identities = 426/426 (100%), Positives = 426/426 (100%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP
Sbjct: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW
Sbjct: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
Query: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL
Sbjct: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
Query: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS
Sbjct: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
Query: 241 RCLQNPLENLELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIA 300
RCLQNPLENLELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIA
Sbjct: 241 RCLQNPLENLELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIA 300
Query: 301 ASLETLILEGCQIHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLCHTSGLSKLS 360
ASLETLILEGCQIHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLCHTSGLSKLS
Sbjct: 301 ASLETLILEGCQIHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLCHTSGLSKLS 360
Query: 361 LETYPAPEESLNSLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEEL 420
LETYPAPEESLNSLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEEL
Sbjct: 361 LETYPAPEESLNSLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEEL 420
Query: 421 ELHLCC 426
ELHLCC
Sbjct: 421 ELHLCC 426
>gi|66954681 PRAME family member 13 [Homo sapiens]
Length = 474
Score = 844 bits (2180), Expect = 0.0
Identities = 425/474 (89%), Positives = 425/474 (89%), Gaps = 48/474 (10%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP
Sbjct: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW
Sbjct: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
Query: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL
Sbjct: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
Query: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS
Sbjct: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
Query: 241 ------------------------------------------------RCLQNPLENLEL 252
RCLQNPLENLEL
Sbjct: 241 RCHHSMSDNELEGRLVTKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL 300
Query: 253 TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEGCQ 312
TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEGCQ
Sbjct: 301 TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEGCQ 360
Query: 313 IHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLCHTSGLSKLSLETYPAPEESLN 372
IHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLL HTSGLSKLSLETYPAPEESLN
Sbjct: 361 IHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLRHTSGLSKLSLETYPAPEESLN 420
Query: 373 SLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLCC 426
SLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLCC
Sbjct: 421 SLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLCC 474
>gi|12738831 PRAME family member 1 [Homo sapiens]
Length = 474
Score = 818 bits (2114), Expect = 0.0
Identities = 413/474 (87%), Positives = 418/474 (88%), Gaps = 48/474 (10%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAF RRHFQTLTVMVQAWP
Sbjct: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFSRRHFQTLTVMVQAWP 60
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW
Sbjct: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
Query: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
ALSCFPET SKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL
Sbjct: 121 ALSCFPETTSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
Query: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
CCSKLVNYLTPIK+LRKSLKIIYLNSIQ+LEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS
Sbjct: 181 CCSKLVNYLTPIKYLRKSLKIIYLNSIQELEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
Query: 241 RC------------------------------------------------LQNPLENLEL 252
RC LQNPLENLEL
Sbjct: 241 RCHHYTSDNELQGRLVAKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL 300
Query: 253 TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEGCQ 312
TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASL+TLILEGCQ
Sbjct: 301 TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLKTLILEGCQ 360
Query: 313 IHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLCHTSGLSKLSLETYPAPEESLN 372
IHYSQLSAILP LS CSQLTTFYFGRNCMS+ ALKDLL HTSGLSKLSLETYPAPEESLN
Sbjct: 361 IHYSQLSAILPALSRCSQLTTFYFGRNCMSIDALKDLLRHTSGLSKLSLETYPAPEESLN 420
Query: 373 SLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLCC 426
SLVRV+WEIF LRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLCC
Sbjct: 421 SLVRVNWEIFTPLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLCC 474
>gi|12738834 PRAME family member 2 [Homo sapiens]
Length = 474
Score = 777 bits (2007), Expect = 0.0
Identities = 395/474 (83%), Positives = 403/474 (85%), Gaps = 48/474 (10%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLF EAF RRHFQTLTVMVQAWP
Sbjct: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFREAFSRRHFQTLTVMVQAWP 60
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
FTCLPL SLMKTLHLE LKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW
Sbjct: 61 FTCLPLVSLMKTLHLEPLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
Query: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
ALSCFPE MSKRQTAEDCPR GEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL
Sbjct: 121 ALSCFPEAMSKRQTAEDCPRTGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
Query: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
CCSKLVNYLTPIK+LRKSLKIIY+NSI +LEI N WP LIRKL CYLKEMK L KLVFS
Sbjct: 181 CCSKLVNYLTPIKYLRKSLKIIYINSIGELEIHNTCWPHLIRKLYCYLKEMKTLCKLVFS 240
Query: 241 RC------------------------------------------------LQNPLENLEL 252
RC LQNPLENLEL
Sbjct: 241 RCHHYTSDNELEGWLVTRFTSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL 300
Query: 253 TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEGCQ 312
T G LLEED+KCLSQ+PSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETL+LEGCQ
Sbjct: 301 TCGNLLEEDLKCLSQFPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLVLEGCQ 360
Query: 313 IHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLCHTSGLSKLSLETYPAPEESLN 372
IHYSQLSAILPGLS CSQLTTFYFG NCMS+ ALKDLL HTSGLSKLSLETYPAPEESLN
Sbjct: 361 IHYSQLSAILPGLSCCSQLTTFYFGSNCMSIDALKDLLRHTSGLSKLSLETYPAPEESLN 420
Query: 373 SLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLCC 426
SLVRV+WEIF LRAELMCTLRE RQPKRIFIGPTPCPSCGSSPSEELELHLCC
Sbjct: 421 SLVRVNWEIFTPLRAELMCTLREFRQPKRIFIGPTPCPSCGSSPSEELELHLCC 474
>gi|239741051 PREDICTED: similar to PRAME family member 10 [Homo
sapiens]
Length = 426
Score = 526 bits (1356), Expect = e-149
Identities = 268/425 (63%), Positives = 314/425 (73%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
MS+QAP RLLELAGQSLLR+Q L+I ++ELPR ++ +FMEAF R F+ L +MVQAWP
Sbjct: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F LPLGSLMKT HLETL+A+L GL L+ QK RPRRWKLQVLDLRDVDENFW W GA
Sbjct: 61 FLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
Query: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
LSC PE MSKRQT EDCPRMGE QPLKVFID+CLKE DECL YLF W++ RRGLVHL
Sbjct: 121 VLSCSPEAMSKRQTVEDCPRMGERQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
Query: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
CCSK+ NY P R L+ IY +SIQ+LE+ K YL +M NLR+L F
Sbjct: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFFP 240
Query: 241 RCLQNPLENLELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIA 300
R L+NPL + YL + DM+CLSQYPSL LK L L ++L++ +LEPLG LLEK+A
Sbjct: 241 RYLKNPLGAFIFSDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTNLEPLGVLLEKVA 300
Query: 301 ASLETLILEGCQIHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLCHTSGLSKLS 360
A+L+TL+L+ C+I QL +LP LSHCSQLTTF F N SM ALKDLL HT GLSKL
Sbjct: 301 ATLKTLVLKDCRIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLG 360
Query: 361 LETYPAPEESLNSLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEEL 420
LE YPAP ESL+ V+WEI +RAELM TLREVRQPKRIF GP PCP+CGS PSE++
Sbjct: 361 LELYPAPLESLDYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGSWPSEKV 420
Query: 421 ELHLC 425
+ HLC
Sbjct: 421 DFHLC 425
>gi|239741055 PREDICTED: similar to PRAME family member 10 [Homo
sapiens]
Length = 426
Score = 526 bits (1354), Expect = e-149
Identities = 268/425 (63%), Positives = 313/425 (73%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
MS+QAP RLLELAGQSLLR+Q L+I ++ELPR ++ +FMEAF R F+ L +MVQAWP
Sbjct: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F LPLGSLMKT HLETL+A+L GL L+ QK RPRRWKLQVLDLRDVDENFW W GA
Sbjct: 61 FLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
Query: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
LSC PE MSKRQT EDCPRMGE QPLKVFID+CLKE DECL YLF W++ RRGLVHL
Sbjct: 121 VLSCSPEAMSKRQTVEDCPRMGERQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
Query: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
CCSK+ NY P R L+ IY +SIQ+LE+ K YL +M NLR+L F
Sbjct: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFFP 240
Query: 241 RCLQNPLENLELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIA 300
R L+NPL + YL + DM+CLSQYPSL LK L L ++L++ LEPLG LLEK+A
Sbjct: 241 RYLKNPLGAFIFSDAYLADRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVA 300
Query: 301 ASLETLILEGCQIHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLCHTSGLSKLS 360
A+L+TL+L+ C+I QL +LP LSHCSQLTTF F N SM ALKDLL HT GLSKL
Sbjct: 301 ATLKTLVLKDCRIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLG 360
Query: 361 LETYPAPEESLNSLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEEL 420
LE YPAP ESL+ V+WEI +RAELM TLREVRQPKRIF GP PCP+CGS PSE++
Sbjct: 361 LELYPAPLESLDYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGSWPSEKV 420
Query: 421 ELHLC 425
+ HLC
Sbjct: 421 DFHLC 425
>gi|157426839 PRAME family member 17 [Homo sapiens]
Length = 474
Score = 516 bits (1329), Expect = e-146
Identities = 271/473 (57%), Positives = 319/473 (67%), Gaps = 48/473 (10%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
MS+Q+P RLLELAGQSLLR+Q L+I ++ELPR ++ +FMEA RHF+ L +MVQAWP
Sbjct: 1 MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F LPLGSLMKT HLETL+A+L+GL LL QK RPRRWKLQVLDLRDVD NFW W GA
Sbjct: 61 FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
Query: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
ALSC PE MSKRQT ED PR GEHQPLKVFID+C KE DECL YL +W++ RRGLVHL
Sbjct: 121 ALSCSPEAMSKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
Query: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
CC+K+ NY P R LK +Y +SIQ+LEI+ K YL +M NLRKL +
Sbjct: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
Query: 241 ------------------------------------------------RCLQNPLENLEL 252
RCL+NPL
Sbjct: 241 FGYDDELYVSGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTFIF 300
Query: 253 TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEGCQ 312
+ YL ++DM+CLSQYPSL LK L+L ++L++ +LEPLGALLEK+AA+LE L L+ CQ
Sbjct: 301 CHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKDCQ 360
Query: 313 IHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLCHTSGLSKLSLETYPAPEESLN 372
I SQL +LP LS CSQLTTFYF N S ALKDLLCHT GLSKL LE YPAP E L+
Sbjct: 361 IQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLECLD 420
Query: 373 SLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLC 425
+ V+WEI A +RAELMCTLREVRQPKRIF GP PCPSCGS PSE+++ HLC
Sbjct: 421 NRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGSWPSEKVDFHLC 473
>gi|113865933 PRAME family member 16 [Homo sapiens]
Length = 474
Score = 514 bits (1324), Expect = e-146
Identities = 270/473 (57%), Positives = 318/473 (67%), Gaps = 48/473 (10%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
MS+Q+P RLLELAGQSLLR+Q L+I ++ELPR ++ +FMEA RHF+ L +MVQAWP
Sbjct: 1 MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F LPLGSLMKT HLETL+A+L+GL LL QK RPRRWKLQVLDLRDVD NFW W GA
Sbjct: 61 FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
Query: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
ALSC PE M KRQT ED PR GEHQPLKVFID+C KE DECL YL +W++ RRGLVHL
Sbjct: 121 ALSCSPEAMRKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
Query: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
CC+K+ NY P R LK +Y +SIQ+LEI+ K YL +M NLRKL +
Sbjct: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
Query: 241 ------------------------------------------------RCLQNPLENLEL 252
RCL+NPL
Sbjct: 241 FGYDDELYVSGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTFIF 300
Query: 253 TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEGCQ 312
+ YL ++DM+CLSQYPSL LK L+L ++L++ +LEPLGALLEK+AA+LE L L+ CQ
Sbjct: 301 CHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKDCQ 360
Query: 313 IHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLCHTSGLSKLSLETYPAPEESLN 372
I SQL +LP LS CSQLTTFYF N S ALKDLLCHT GLSKL LE YPAP E L+
Sbjct: 361 IQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLECLD 420
Query: 373 SLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLC 425
+ V+WEI A +RAELMCTLREVRQPKRIF GP PCPSCGS PSE+++ HLC
Sbjct: 421 NRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGSWPSEKVDFHLC 473
>gi|194018546 PRAME family member 10 [Homo sapiens]
Length = 474
Score = 508 bits (1309), Expect = e-144
Identities = 269/473 (56%), Positives = 315/473 (66%), Gaps = 48/473 (10%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
MS+QAP RLLELAGQSLLR+Q L+I ++ELPR ++ +FMEAF R F+ L +MVQAWP
Sbjct: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F LPLGSLMKTLHLETL+A+L GL L+ QK RPRRWKLQVLDLRDVDENFW W GA
Sbjct: 61 FLSLPLGSLMKTLHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
Query: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
LSC PE MSKRQT EDCPRMGEHQPLKVFID+CLKE DECL YLF W++ RRGLVHL
Sbjct: 121 VLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
Query: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
CCSK+ NY P R L+ IY +SIQ+LE+ K YL +M NLR+L +
Sbjct: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLA 240
Query: 241 ------------------------------------------------RCLQNPLENLEL 252
R L+NPL
Sbjct: 241 FGYERELYVSVQWPCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAFIF 300
Query: 253 TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEGCQ 312
+ YL + DM+CLSQYPSL LK L L ++L++ LEPLG LLEK+AA+L+TL+L+ C+
Sbjct: 301 SDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDCR 360
Query: 313 IHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLCHTSGLSKLSLETYPAPEESLN 372
I QL +LP LSHCSQLTTF F N SM ALKDLL HT GLSKL LE YPAP ESL+
Sbjct: 361 IQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTGGLSKLGLELYPAPLESLD 420
Query: 373 SLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLC 425
V+WEI +RAELM TLREVRQPKRIF GP PCP+CGS PSE+++ HLC
Sbjct: 421 YKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPNCGSWPSEKVDFHLC 473
>gi|154800493 PRAME family member 22 [Homo sapiens]
Length = 481
Score = 486 bits (1252), Expect = e-137
Identities = 266/473 (56%), Positives = 310/473 (65%), Gaps = 48/473 (10%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
MS+QAP RLLELAGQSLL DQAL+IS ++ELPR L+ PLF+EAF R + L VMVQAWP
Sbjct: 3 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F CLPLGSLMKT LE L +++G+ LL QK RPRRWKLQVL+LRDVDENFW W GA
Sbjct: 63 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSGAR 122
Query: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
LSC PE MSKRQT EDCPR GE QPLKVF+D+CLKE DE L + WV RRG VHL
Sbjct: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182
Query: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
CC+K+VNY I + R L+ +Y +SIQ LEI NM WP +I + YL +M+NLRKL S
Sbjct: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSRYLSQMRNLRKLFIS 242
Query: 241 ------------------------------------------------RCLQNPLENLEL 252
RCL++PLE L L
Sbjct: 243 DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETLAL 302
Query: 253 TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEGCQ 312
TYG+L + D+KCL +YPSL LK LNLS+ L I LEPL ALLEK+AA+L+TL L C
Sbjct: 303 TYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVDCG 362
Query: 313 IHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLCHTSGLSKLSLETYPAPEESLN 372
I S+L ILP LS CS LTTF F N SM LKDLL HT LS LSLETYPAP ESL+
Sbjct: 363 IRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 422
Query: 373 SLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLC 425
RV E+ L+AELM LREVR+PKRIF GP CP CG+SP+E+LE + C
Sbjct: 423 DRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFC 475
>gi|194306635 PRAME family member 19 [Homo sapiens]
Length = 479
Score = 486 bits (1251), Expect = e-137
Identities = 266/473 (56%), Positives = 308/473 (65%), Gaps = 48/473 (10%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
MS QAP RLLELAGQSLLRDQAL+IS ++ELPR L+ LF+EAF R + L VMVQAWP
Sbjct: 1 MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F CLPLGSLMKT LE L +++G+ LL QK RPRRWKLQVL++RDVDENFW W GA
Sbjct: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
Query: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
LSC PE MSKRQT EDCPR GE QPLKVF+D+CLKE DE L + WV RR VHL
Sbjct: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
Query: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
CC+K+VNY I + R L+ +Y +SIQ LEI NM WP ++ ++ YL +MKNLRKL S
Sbjct: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSRYLSQMKNLRKLFIS 240
Query: 241 ------------------------------------------------RCLQNPLENLEL 252
RCL++PLE L L
Sbjct: 241 DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLETLAL 300
Query: 253 TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEGCQ 312
TYG L EED+KCL YPSL LK LNLS+ L I LEPL ALLEK+AA+L+TL L C
Sbjct: 301 TYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLVDCG 360
Query: 313 IHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLCHTSGLSKLSLETYPAPEESLN 372
I YS+L ILP LS CS LTTF F N SM LKDLL HT LS LSLETYPAP ESL+
Sbjct: 361 IGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 420
Query: 373 SLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLC 425
+ RV E+ L+AELM LREVR+P RIF GP CP CG SP+E+LE + C
Sbjct: 421 NRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFC 473
>gi|153791443 PRAME family member 18 [Homo sapiens]
Length = 479
Score = 482 bits (1241), Expect = e-136
Identities = 265/473 (56%), Positives = 307/473 (64%), Gaps = 48/473 (10%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
MS QAP RLLELAGQSLLRDQAL+IS ++ELPR L+ LF+EAF R + L VMVQAWP
Sbjct: 1 MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F CLPLGSLMKT LE L +++G+ LL QK RPRRWKLQVL++RDVDENFW W GA
Sbjct: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
Query: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
LSC PE MSKRQT EDCPR GE QPLKVF+D+CLKE DE L + WV RR VHL
Sbjct: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
Query: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
CC+K+VNY I + R L+ +Y +SIQ LEI NM WP ++ ++ YL +MKNLRKL S
Sbjct: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSRYLSQMKNLRKLFIS 240
Query: 241 ------------------------------------------------RCLQNPLENLEL 252
RCL++PLE L L
Sbjct: 241 DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLETLAL 300
Query: 253 TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEGCQ 312
TYG L EED+KCL YPSL LK LNLS+ L I LEPL ALLEK+AA+L+TL L C
Sbjct: 301 TYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLVDCG 360
Query: 313 IHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLCHTSGLSKLSLETYPAPEESLN 372
I S+L ILP LS CS LTTF F N SM LKDLL HT LS LSLETYPAP ESL+
Sbjct: 361 IGDSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 420
Query: 373 SLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLC 425
+ RV E+ L+AELM LREVR+P RIF GP CP CG SP+E+LE + C
Sbjct: 421 NRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFC 473
>gi|194306638 PRAME family member 3 [Homo sapiens]
Length = 481
Score = 480 bits (1236), Expect = e-136
Identities = 265/473 (56%), Positives = 309/473 (65%), Gaps = 48/473 (10%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
MS+QAP RLLELAGQSLL DQAL+IS ++ELPR L+ PLF+EAF R + L VMVQAWP
Sbjct: 3 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F CLPLGSLMKT LE L +++G+ LL QK RPRR KLQVL+LRDVDENFW W GA
Sbjct: 63 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSGAR 122
Query: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
LSC PE MSKRQT EDCPR GE QPLKVF+D+CLKE DE L + WV RRG VHL
Sbjct: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182
Query: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
CC+K+VNY I + R L+ +Y +SIQ LEI NM WP +I + YL +M+NLRKL S
Sbjct: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFIRYLSQMRNLRKLFIS 242
Query: 241 ------------------------------------------------RCLQNPLENLEL 252
RCL++PLE L L
Sbjct: 243 DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETLAL 302
Query: 253 TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEGCQ 312
TYG+L + D+KCL +YPSL LK LNLS+ L I LEPL ALLEK+AA+L+TL L C
Sbjct: 303 TYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVDCG 362
Query: 313 IHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLCHTSGLSKLSLETYPAPEESLN 372
I S+L ILP LS CS LTTF F N SM LKDLL HT LS LSLETYPAP ESL+
Sbjct: 363 IRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 422
Query: 373 SLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLC 425
RV E+ L+AELM LREVR+PKRIF GP CP CG+SP+E+LE + C
Sbjct: 423 DRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFC 475
>gi|239741047 PREDICTED: PRAME family member 25-like [Homo sapiens]
Length = 474
Score = 424 bits (1089), Expect = e-118
Identities = 242/474 (51%), Positives = 291/474 (61%), Gaps = 48/474 (10%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
MS+QAP RLLELAGQSLL DQAL+IS ++ELPR L+ PLF+EAF R + L VMVQAWP
Sbjct: 1 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 60
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F CLPLGSLMKT LE L +++G+ LL QK RPRR KLQVL+LRDVDENFW W GA
Sbjct: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSGAR 120
Query: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
LSC PE MSKRQT EDCPR GE QPLKVF+D+CLKE DE L + WV RRG VHL
Sbjct: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 180
Query: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
CC+K+VNY I + R L+ +Y +SIQ LEI NM WP +I + YL +M+NLRKL S
Sbjct: 181 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSPYLSQMRNLRKLFIS 240
Query: 241 -----------------------------------------------RCLQNPLENLELT 253
CL+ L+ L +T
Sbjct: 241 DGCRYLLSSDSQEQIAPFTTQFLKLHCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLTIT 300
Query: 254 YGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEGCQI 313
LLE D+K LSQ PS+ LK L+LS + L SL PL LLEK+AA+LE L L+ C I
Sbjct: 301 NCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDCGI 360
Query: 314 HYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLCHTSGLSKLSLETYPAPEESLNS 373
SQ++AILP LS C +L TF F N +SM L++LL HT L L LE YPAP ES +
Sbjct: 361 IDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCLELYPAPRESYGA 420
Query: 374 LVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELEL-HLCC 426
+ W F +RAELM +R++R PKRI G CP CG+ +LE CC
Sbjct: 421 DGTLCWSRFTQIRAELMKRVRDLRHPKRILFGTDYCPDCGNRSFYDLEADQYCC 474
>gi|124249372 PRAME family member 12 [Homo sapiens]
Length = 483
Score = 412 bits (1060), Expect = e-115
Identities = 240/480 (50%), Positives = 296/480 (61%), Gaps = 56/480 (11%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
MS+QAPPRLLELA QSLLRD+AL+I +EELPR L+ PLFMEAF RR +TLT MVQAWP
Sbjct: 1 MSLQAPPRLLELAEQSLLRDRALAIPTLEELPRELFPPLFMEAFTRRCCETLTTMVQAWP 60
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
FTCLPLGSLMK+ +LE +A+LEGL LL QK RPRRWKLQVLDLR+VDENFW W GA
Sbjct: 61 FTCLPLGSLMKSCNLEIFRAVLEGLDALLAQKVRPRRWKLQVLDLRNVDENFWGIWSGAS 120
Query: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
ALS PE +SKR+TA +CPR G QPL V +D+C K DECL + +W QR+GL+H+
Sbjct: 121 ALS--PEALSKRRTAGNCPRPGGQQPLMVILDLCFKNGMLDECLTHFLEWGKQRKGLLHV 178
Query: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLV-- 238
CC +L + I + + L + L+ IQ++E+ ++ + YL +M+NLRKLV
Sbjct: 179 CCKELQIFGIAIHRIIEVLNTVELDCIQEVEVCCPWELSILIRFAPYLGQMRNLRKLVLF 238
Query: 239 -----------------------------------------------FSRCLQNPLENLE 251
RCLQ PLE +
Sbjct: 239 NIHVSACIPLDRKEQFVIQFTSQFLKLDYFQKLYMHSVSFLEGHLDQLLRCLQAPLETVV 298
Query: 252 LTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEGC 311
+T L E D+K LS PS+ LK L+L + L S EPL LLE+ A+L+TL LE C
Sbjct: 299 MTECLLSESDLKHLSWCPSIRQLKELDLRGITLTHFSPEPLSVLLEQAEATLQTLDLEDC 358
Query: 312 QIHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLCHTSGLSKLSLETYPAPEESL 371
I SQLSAILP LS CSQL+TF F N +SM AL++LL HT GLSKLSLE YPAP ES
Sbjct: 359 GIVDSQLSAILPALSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESY 418
Query: 372 NSLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELE-----LHLCC 426
++ + W F+ L AELM TLR++RQPK I PCP CG S +LE L+ CC
Sbjct: 419 DAQGALCWGRFSQLGAELMKTLRDLRQPKIIVFSTVPCPRCGIRASYDLEPSHCLLNACC 478
>gi|239741053 PREDICTED: similar to Putative PRAME family member 24
[Homo sapiens]
Length = 474
Score = 395 bits (1014), Expect = e-110
Identities = 237/474 (50%), Positives = 294/474 (62%), Gaps = 51/474 (10%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
MSI+APPRLLELA Q LLRDQAL+IS MEELPR L+ LFMEAF RR +TL MVQAWP
Sbjct: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
FT LPLGSLMK+ HLE+LK++LEG+ +LLTQ+ RPR+ KLQVLDLR+VDENF + GA
Sbjct: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120
Query: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
A FPE +S++QTA++CP G QP VFID+CLK DECL +L +W QR+GL+H+
Sbjct: 121 A--SFPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178
Query: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLV-- 238
CC +L + PI + + L ++ L+ IQ++E+ + K YL +M+NLRKLV
Sbjct: 179 CCKELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMRNLRKLVLF 238
Query: 239 -----------------------------------------------FSRCLQNPLENLE 251
RCLQ LE +
Sbjct: 239 NIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLEMVV 298
Query: 252 LTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEGC 311
+T L E D+K LS PS+ LK L+L V L S EPL LLE++ A+L+TL LE C
Sbjct: 299 MTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDLEDC 358
Query: 312 QIHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLCHTSGLSKLSLETYPAPEESL 371
I SQLSAILP LS CSQL+TF F N +SM AL++LL HT GLSKLSLE YPAP ES
Sbjct: 359 GIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESY 418
Query: 372 NSLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLC 425
++ + W FA L AELM TLR++RQPK I PCP CG S +LE C
Sbjct: 419 DTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHC 472
>gi|59676587 PRAME family member 8 [Homo sapiens]
Length = 474
Score = 395 bits (1014), Expect = e-110
Identities = 237/474 (50%), Positives = 294/474 (62%), Gaps = 51/474 (10%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
MSI+APPRLLELA Q LLRDQAL+IS MEELPR L+ LFMEAF RR +TL MVQAWP
Sbjct: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
FT LPLGSLMK+ HLE+LK++LEG+ +LLTQ+ RPR+ KLQVLDLR+VDENF + GA
Sbjct: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120
Query: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
A FPE +S++QTA++CP G QP VFID+CLK DECL +L +W QR+GL+H+
Sbjct: 121 A--SFPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178
Query: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLV-- 238
CC +L + PI + + L ++ L+ IQ++E+ + K YL +M+NLRKLV
Sbjct: 179 CCQELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMRNLRKLVLF 238
Query: 239 -----------------------------------------------FSRCLQNPLENLE 251
RCLQ LE +
Sbjct: 239 NIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLEMVV 298
Query: 252 LTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEGC 311
+T L E D+K LS PS+ LK L+L V L S EPL LLE++ A+L+TL LE C
Sbjct: 299 MTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDLEDC 358
Query: 312 QIHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLCHTSGLSKLSLETYPAPEESL 371
I SQLSAILP LS CSQL+TF F N +SM AL++LL HT GLSKLSLE YPAP ES
Sbjct: 359 GIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESY 418
Query: 372 NSLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLC 425
++ + W FA L AELM TLR++RQPK I PCP CG S +LE C
Sbjct: 419 DTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHC 472
>gi|59676593 PRAME family member 7 [Homo sapiens]
Length = 474
Score = 392 bits (1007), Expect = e-109
Identities = 236/474 (49%), Positives = 293/474 (61%), Gaps = 51/474 (10%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
MSI+APPRLLELA Q LLRDQAL+IS MEELPR L+ LFMEAF RR +TL MVQAWP
Sbjct: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
FT LPLGSLMK+ HLE+LK++LEG+ +LLTQ+ RPR+ KLQVLDLR+VDENF + GA
Sbjct: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120
Query: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
A FPE +S++QTA++CP G QP VFID+CLK DECL +L +W QR+GL+H+
Sbjct: 121 A--SFPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178
Query: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLV-- 238
CC +L + PI + + L ++ L+ IQ++E+ + K YL +M+NLRKLV
Sbjct: 179 CCKELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMRNLRKLVLF 238
Query: 239 -----------------------------------------------FSRCLQNPLENLE 251
RCLQ LE +
Sbjct: 239 NIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLEMVV 298
Query: 252 LTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEGC 311
+T L E D+K LS PS+ LK L+L V L S EPL LLE++ A+L+TL LE C
Sbjct: 299 MTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDLEDC 358
Query: 312 QIHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLCHTSGLSKLSLETYPAPEESL 371
I SQLSAILP LS CSQL+TF F N +SM AL++LL HT GLSKLSLE YPAP ES
Sbjct: 359 GIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESY 418
Query: 372 NSLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLC 425
++ + W FA L AELM T R++RQPK I PCP CG S +LE C
Sbjct: 419 DTQGALCWGRFAELGAELMKTPRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHC 472
>gi|153792112 PRAME family member 20 [Homo sapiens]
Length = 475
Score = 385 bits (989), Expect = e-107
Identities = 227/475 (47%), Positives = 280/475 (58%), Gaps = 50/475 (10%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
MSI+ PPRLLELAG+SLLRD+AL+IS +EELP L+ PLFMEAF RRH + L +MVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWP 60
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F LPLGSLMK ET +A+L+GL LLT + R RRWKLQVLDL+DV ENFW W A
Sbjct: 61 FLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAM 120
Query: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
A C P M R+ +DCPRM QPL VFID+CLK DE LF WV QR GLVHL
Sbjct: 121 ARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHL 180
Query: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWP-RLIRKLRCYLKEMKNLRKLVF 239
CC KL ++R LK + L+ IQ++E+ N +W ++ + YL +M+NLRKLV
Sbjct: 181 CCKKLKMLGMLFHNIRNILKTVNLDCIQEVEV-NCNWTLPVLAEFTPYLGQMRNLRKLVL 239
Query: 240 S------------------------------------------------RCLQNPLENLE 251
S CL+ L L
Sbjct: 240 SDIDSRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNILA 299
Query: 252 LTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEGC 311
+T LLE D+K LS+YPS+G LK L+LS L SL PL LLEK+AA+LE L L+ C
Sbjct: 300 ITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDDC 359
Query: 312 QIHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLCHTSGLSKLSLETYPAPEESL 371
I SQ++AILP LS C +LTTF F N +S L++LLCHT L+ L LE YPAP ES
Sbjct: 360 GIVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRESY 419
Query: 372 NSLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLCC 426
+ V FA L AELM +R +R+P+RI CP CG+ +LE+ CC
Sbjct: 420 DVRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGNRSLYDLEVDRCC 474
>gi|153945800 PRAME family member 21 [Homo sapiens]
Length = 475
Score = 385 bits (989), Expect = e-107
Identities = 227/475 (47%), Positives = 280/475 (58%), Gaps = 50/475 (10%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
MSI+ PPRLLELAG+SLLRD+AL+IS +EELP L+ PLFMEAF RRH + L +MVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWP 60
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F LPLGSLMK ET +A+L+GL LLT + R RRWKLQVLDL+DV ENFW W A
Sbjct: 61 FLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAM 120
Query: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
A C P M R+ +DCPRM QPL VFID+CLK DE LF WV QR GLVHL
Sbjct: 121 ARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHL 180
Query: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWP-RLIRKLRCYLKEMKNLRKLVF 239
CC KL ++R LK + L+ IQ++E+ N +W ++ + YL +M+NLRKLV
Sbjct: 181 CCKKLKMLGMLFHNIRNILKTVNLDCIQEVEV-NCNWTLPVLAEFTPYLGQMRNLRKLVL 239
Query: 240 S------------------------------------------------RCLQNPLENLE 251
S CL+ L L
Sbjct: 240 SDIDSRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNILA 299
Query: 252 LTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEGC 311
+T LLE D+K LS+YPS+G LK L+LS L SL PL LLEK+AA+LE L L+ C
Sbjct: 300 ITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDDC 359
Query: 312 QIHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLCHTSGLSKLSLETYPAPEESL 371
I SQ++AILP LS C +LTTF F N +S L++LLCHT L+ L LE YPAP ES
Sbjct: 360 GIVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRESY 419
Query: 372 NSLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLCC 426
+ V FA L AELM +R +R+P+RI CP CG+ +LE+ CC
Sbjct: 420 DVRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGNRSLYDLEVDRCC 474
>gi|61696142 PRAME family member 5 [Homo sapiens]
Length = 476
Score = 364 bits (934), Expect = e-101
Identities = 215/476 (45%), Positives = 276/476 (57%), Gaps = 51/476 (10%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
MSI+ PPRLLELAG+SLLRDQAL++S +EELP L+ PLFMEAF RR + L +MVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F LPL L+K LE +A+L+GL LLTQ PRRWKLQVLDL+DV ENFW W A
Sbjct: 61 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
Query: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
A CF ++ +DCPRM QPL VF+++ LK DE L L WV QR+ L+HL
Sbjct: 121 AHGCFLNAKRNKKPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
Query: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPR-LIRKLRCYLKEMKNLRKLVF 239
CC KL P +++R LK++ L+ IQ++E+ N W ++ + YL M+NL+KLV
Sbjct: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKLVL 239
Query: 240 SR-------------------------------------------------CLQNPLENL 250
S CL+ L+ L
Sbjct: 240 SHMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVL 299
Query: 251 ELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEG 310
+T LLE D+K LSQ PS+ LK L+LS + L SL PL LLEK+AA+LE L L+
Sbjct: 300 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 359
Query: 311 CQIHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLCHTSGLSKLSLETYPAPEES 370
C I SQ++AILP LS C +L TF F N +SM L++LL HT L L +E YPAP ES
Sbjct: 360 CGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRES 419
Query: 371 LNSLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLCC 426
++ + W FA +RAELM +R++R PKRI CP CG+ +LE CC
Sbjct: 420 YDADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQCC 475
>gi|58219004 PRAME family member 6 [Homo sapiens]
Length = 476
Score = 363 bits (933), Expect = e-100
Identities = 215/476 (45%), Positives = 275/476 (57%), Gaps = 51/476 (10%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
MSI+ PPRLLELAG+SLLRDQAL++S +EELP L+ PLFMEAF RR + L +MVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F LPL L+K LE +A+L+GL LLTQ PRRWKLQVLDL+DV ENFW W A
Sbjct: 61 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
Query: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
A CF + +DCPRM QPL VF+++ LK DE L L WV QR+ L+HL
Sbjct: 121 ARGCFLNAKRNKTPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
Query: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPR-LIRKLRCYLKEMKNLRKLVF 239
CC KL P +++R LK++ L+ IQ++E+ N W ++ + YL M+NL+KLV
Sbjct: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKLVL 239
Query: 240 SR-------------------------------------------------CLQNPLENL 250
S CL+ L+ L
Sbjct: 240 SHMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVL 299
Query: 251 ELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEG 310
+T LLE D+K LSQ PS+ LK L+LS + L SL PL LLEK+AA+LE L L+
Sbjct: 300 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 359
Query: 311 CQIHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLCHTSGLSKLSLETYPAPEES 370
C I SQ++AILP LS C +L TF F N +SM L++LL HT L L +E YPAP ES
Sbjct: 360 CGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRES 419
Query: 371 LNSLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLCC 426
++ + W FA +RAELM +R++R PKRI CP CG+ +LE CC
Sbjct: 420 YDADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQCC 475
>gi|148356236 PRAME family member 15 [Homo sapiens]
Length = 478
Score = 363 bits (932), Expect = e-100
Identities = 216/477 (45%), Positives = 276/477 (57%), Gaps = 52/477 (10%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
MSI+ PPRLLELAG+SLLRDQAL++S +EELP L+ PLFMEAF RR + L +MVQAWP
Sbjct: 3 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 62
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F LPL L+K LE +A+L+GL LLTQ RPRRWKLQVLDL+DV ENFW W A
Sbjct: 63 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
Query: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
A CF ++ +DCPRM QPL VF+++ LK DE L YL WV QR+ L+HL
Sbjct: 123 AHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLLHL 182
Query: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWP-RLIRKLRCYLKEMKNLRKLVF 239
CC KL P +++R LK++ L+ IQ++E+ N W ++ + YL M+NL+KLV
Sbjct: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKLVL 241
Query: 240 SR-------------------------------------------------CLQNPLENL 250
S CL+ L+ L
Sbjct: 242 SHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVL 301
Query: 251 ELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEG 310
+T LLE D+K LSQ PS+ LK L+LS + L SL PL LLEK+AA+LE L L+
Sbjct: 302 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 361
Query: 311 CQIHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLCHTSGLSKLSLETYPAPEES 370
C I SQ++AILP LS C +L TF F N + M L++LL HT L L +E YPAP ES
Sbjct: 362 CGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRES 421
Query: 371 LNSLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELEL-HLCC 426
+ + W FA +RAELM +R++R PKRI CP CG+ +LE CC
Sbjct: 422 YGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC 478
>gi|61102721 PRAME family member 9 [Homo sapiens]
Length = 478
Score = 363 bits (932), Expect = e-100
Identities = 216/477 (45%), Positives = 276/477 (57%), Gaps = 52/477 (10%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
MSI+ PPRLLELAG+SLLRDQAL++S +EELP L+ PLFMEAF RR + L +MVQAWP
Sbjct: 3 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 62
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F LPL L+K LE +A+L+GL LLTQ RPRRWKLQVLDL+DV ENFW W A
Sbjct: 63 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
Query: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
A CF ++ +DCPRM QPL VF+++ LK DE L YL WV QR+ L+HL
Sbjct: 123 AHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLLHL 182
Query: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWP-RLIRKLRCYLKEMKNLRKLVF 239
CC KL P +++R LK++ L+ IQ++E+ N W ++ + YL M+NL+KLV
Sbjct: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKLVL 241
Query: 240 SR-------------------------------------------------CLQNPLENL 250
S CL+ L+ L
Sbjct: 242 SHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVL 301
Query: 251 ELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEG 310
+T LLE D+K LSQ PS+ LK L+LS + L SL PL LLEK+AA+LE L L+
Sbjct: 302 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 361
Query: 311 CQIHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLCHTSGLSKLSLETYPAPEES 370
C I SQ++AILP LS C +L TF F N + M L++LL HT L L +E YPAP ES
Sbjct: 362 CGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRES 421
Query: 371 LNSLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELEL-HLCC 426
+ + W FA +RAELM +R++R PKRI CP CG+ +LE CC
Sbjct: 422 YGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC 478
>gi|239741045 PREDICTED: PRAME family member 23 [Homo sapiens]
Length = 476
Score = 361 bits (926), Expect = e-100
Identities = 214/476 (44%), Positives = 275/476 (57%), Gaps = 51/476 (10%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
MSI+ PPRLLELAG+SLLRDQAL++S +EELP L+ PLFMEAF RR + L +MVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F LPL L+K LE +A+L+GL LLTQ PRRWKLQVLDL+DV ENFW W A
Sbjct: 61 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
Query: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
A CF ++ +DCPRM QPL VF+++ LK DE L L WV QR+ L+HL
Sbjct: 121 AHGCFLNAKRNKKPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
Query: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPR-LIRKLRCYLKEMKNLRKLVF 239
CC KL P +++R LK++ L+ IQ++E+ N W ++ + YL M+NL+KLV
Sbjct: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKLVL 239
Query: 240 SR-------------------------------------------------CLQNPLENL 250
S CL+ L+ L
Sbjct: 240 SHMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVL 299
Query: 251 ELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEG 310
+T LLE D+K LSQ PS+ LK L+LS + L SL PL LLEK+AA+LE L L+
Sbjct: 300 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 359
Query: 311 CQIHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLCHTSGLSKLSLETYPAPEES 370
C I SQ++AILP LS C +L TF F N +SM L++LL HT L L +E YPAP ES
Sbjct: 360 CGIIDSQVNAILPALSCCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRES 419
Query: 371 LNSLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLCC 426
++ + W F +RAELM +R++R PKRI CP CG+ +LE CC
Sbjct: 420 YDADGTLCWSRFPQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQCC 475
>gi|239741043 PREDICTED: PRAME family member 11 [Homo sapiens]
Length = 513
Score = 356 bits (914), Expect = 2e-98
Identities = 215/477 (45%), Positives = 272/477 (57%), Gaps = 52/477 (10%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
MSI+ PPRLLEL G+SLLRDQAL++S +EELP L+ PLFMEAF RR + L +MVQAWP
Sbjct: 38 MSIRIPPRLLELXGRSLLRDQALAVSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 97
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F LPL L+K LE +A+L+GL LLTQ RPRRWKLQVLDL+DV ENFW W A
Sbjct: 98 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 157
Query: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
A CF + +DCPRM E QPL VF+++ LK DE L L WV QRR L+HL
Sbjct: 158 AHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTLDEYLTCLLLWVKQRRDLLHL 217
Query: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSW-PRLIRKLRCYLKEMKNLRKLVF 239
CC KL P +++R LK++ L+ IQ++E+ N W ++ + YL ++NL+KLV
Sbjct: 218 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWILPILTQFTPYLGHLRNLQKLVL 276
Query: 240 SR-------------------------------------------------CLQNPLENL 250
S CL+ L+ L
Sbjct: 277 SHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVL 336
Query: 251 ELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEG 310
+T LLE D+K LSQ PS+ LK L+LS + L SL PL LLEK+AA+LE L L+
Sbjct: 337 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 396
Query: 311 CQIHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLCHTSGLSKLSLETYPAPEES 370
C I SQ++AILP LS C +L TF F N + M L++LL HT L L LE YPAP+ES
Sbjct: 397 CGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCLELYPAPQES 456
Query: 371 LNSLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELEL-HLCC 426
+ + W FA +RAELM +R +R PKRI CP G +LE CC
Sbjct: 457 YGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPDHGDRSFYDLEADQYCC 513
>gi|59958373 PRAME family member 4 [Homo sapiens]
Length = 478
Score = 353 bits (907), Expect = 1e-97
Identities = 212/477 (44%), Positives = 272/477 (57%), Gaps = 52/477 (10%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
MSI PPRLLELAG+SLLRDQAL++S +EELP L+ PLFMEAF RR + L +MVQ+WP
Sbjct: 3 MSIWTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQSWP 62
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F LPL L+K LE +A+L+GL LL RPRRWKLQVLDL+DV ENFW W A
Sbjct: 63 FRRLPLRPLIKMPCLEAFQAVLDGLDALLNLGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
Query: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
A CF ++ EDCPRM QPL VF+++ LK DE L L WV QR+ L+HL
Sbjct: 123 AHGCFLNAKRNKKPVEDCPRMRGRQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 182
Query: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPR-LIRKLRCYLKEMKNLRKLVF 239
CC KL P +++R LK++ L+ IQ++E+ N W ++ + YL M+NL+KL+
Sbjct: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKLIL 241
Query: 240 SR-------------------------------------------------CLQNPLENL 250
S CL+ L+ L
Sbjct: 242 SHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKFL 301
Query: 251 ELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEG 310
+T LLE D+K LSQ PS+ LK L+LS + L SL PL LLEK+AA+LE L L+
Sbjct: 302 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 361
Query: 311 CQIHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLCHTSGLSKLSLETYPAPEES 370
C I SQ++AILP LS C +L TF F N + M L++LL HT L L +E YPAP ES
Sbjct: 362 CGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRES 421
Query: 371 LNSLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELEL-HLCC 426
+ + W FA +RAELM +R++R PKRI CP CG+ +LE CC
Sbjct: 422 YGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC 478
>gi|46249373 preferentially expressed antigen in melanoma [Homo
sapiens]
Length = 509
Score = 311 bits (798), Expect = 6e-85
Identities = 202/482 (41%), Positives = 271/482 (56%), Gaps = 61/482 (12%)
Query: 5 APPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWPFTCL 64
+P RL+ELAGQSLL+D+AL+I+A+E LPR L+ PLFM AF RH QTL MVQAWPFTCL
Sbjct: 22 SPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAWPFTCL 81
Query: 65 PLGSLMK--TLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLR-DVDENFWARWPGAWA 121
PLG LMK LHLET KA+L+GL +LL Q+ RPRRWKLQVLDLR + ++FW W G A
Sbjct: 82 PLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVWSGNRA 141
Query: 122 -LSCFPE-----TMSKRQTAEDCPRMGEHQ--PLKVFIDICLKEIPQDECLRYLFQWVYQ 173
L FPE M+K++ + E P++V +D+ LKE DE YL + V +
Sbjct: 142 SLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLIEKVKR 201
Query: 174 RRGLVHLCCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKN 233
++ ++ LCC KL + P++ ++ LK++ L+SI+ LE+ + K YL +M N
Sbjct: 202 KKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYLGQMIN 261
Query: 234 LRKLVFS---------------------------RCLQ---------------------- 244
LR+L+ S +CLQ
Sbjct: 262 LRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQLLRHVM 321
Query: 245 NPLENLELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLE 304
NPLE L +T L E D+ LSQ PS+ L L+LS V+L +S EPL ALLE+ +A+L+
Sbjct: 322 NPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERASATLQ 381
Query: 305 TLILEGCQIHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLCHTSGLSKLSLETY 364
L+ + C I QL A+LP LSHCSQLTT F N +S+ AL+ LL H GLS L+ Y
Sbjct: 382 DLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNLTHVLY 441
Query: 365 PAPEESLNSL-VRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELH 423
P P ES + + E A L A L L E+ +P +++ PCP CG + E
Sbjct: 442 PVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGDRTFYDPEPI 501
Query: 424 LC 425
LC
Sbjct: 502 LC 503
>gi|46249371 preferentially expressed antigen in melanoma [Homo
sapiens]
Length = 509
Score = 311 bits (798), Expect = 6e-85
Identities = 202/482 (41%), Positives = 271/482 (56%), Gaps = 61/482 (12%)
Query: 5 APPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWPFTCL 64
+P RL+ELAGQSLL+D+AL+I+A+E LPR L+ PLFM AF RH QTL MVQAWPFTCL
Sbjct: 22 SPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAWPFTCL 81
Query: 65 PLGSLMK--TLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLR-DVDENFWARWPGAWA 121
PLG LMK LHLET KA+L+GL +LL Q+ RPRRWKLQVLDLR + ++FW W G A
Sbjct: 82 PLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVWSGNRA 141
Query: 122 -LSCFPE-----TMSKRQTAEDCPRMGEHQ--PLKVFIDICLKEIPQDECLRYLFQWVYQ 173
L FPE M+K++ + E P++V +D+ LKE DE YL + V +
Sbjct: 142 SLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLIEKVKR 201
Query: 174 RRGLVHLCCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKN 233
++ ++ LCC KL + P++ ++ LK++ L+SI+ LE+ + K YL +M N
Sbjct: 202 KKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYLGQMIN 261
Query: 234 LRKLVFS---------------------------RCLQ---------------------- 244
LR+L+ S +CLQ
Sbjct: 262 LRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQLLRHVM 321
Query: 245 NPLENLELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLE 304
NPLE L +T L E D+ LSQ PS+ L L+LS V+L +S EPL ALLE+ +A+L+
Sbjct: 322 NPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERASATLQ 381
Query: 305 TLILEGCQIHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLCHTSGLSKLSLETY 364
L+ + C I QL A+LP LSHCSQLTT F N +S+ AL+ LL H GLS L+ Y
Sbjct: 382 DLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNLTHVLY 441
Query: 365 PAPEESLNSL-VRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELH 423
P P ES + + E A L A L L E+ +P +++ PCP CG + E
Sbjct: 442 PVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGDRTFYDPEPI 501
Query: 424 LC 425
LC
Sbjct: 502 LC 503
>gi|46249369 preferentially expressed antigen in melanoma [Homo
sapiens]
Length = 509
Score = 311 bits (798), Expect = 6e-85
Identities = 202/482 (41%), Positives = 271/482 (56%), Gaps = 61/482 (12%)
Query: 5 APPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWPFTCL 64
+P RL+ELAGQSLL+D+AL+I+A+E LPR L+ PLFM AF RH QTL MVQAWPFTCL
Sbjct: 22 SPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAWPFTCL 81
Query: 65 PLGSLMK--TLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLR-DVDENFWARWPGAWA 121
PLG LMK LHLET KA+L+GL +LL Q+ RPRRWKLQVLDLR + ++FW W G A
Sbjct: 82 PLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVWSGNRA 141
Query: 122 -LSCFPE-----TMSKRQTAEDCPRMGEHQ--PLKVFIDICLKEIPQDECLRYLFQWVYQ 173
L FPE M+K++ + E P++V +D+ LKE DE YL + V +
Sbjct: 142 SLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLIEKVKR 201
Query: 174 RRGLVHLCCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKN 233
++ ++ LCC KL + P++ ++ LK++ L+SI+ LE+ + K YL +M N
Sbjct: 202 KKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYLGQMIN 261
Query: 234 LRKLVFS---------------------------RCLQ---------------------- 244
LR+L+ S +CLQ
Sbjct: 262 LRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQLLRHVM 321
Query: 245 NPLENLELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLE 304
NPLE L +T L E D+ LSQ PS+ L L+LS V+L +S EPL ALLE+ +A+L+
Sbjct: 322 NPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERASATLQ 381
Query: 305 TLILEGCQIHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLCHTSGLSKLSLETY 364
L+ + C I QL A+LP LSHCSQLTT F N +S+ AL+ LL H GLS L+ Y
Sbjct: 382 DLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNLTHVLY 441
Query: 365 PAPEESLNSL-VRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELH 423
P P ES + + E A L A L L E+ +P +++ PCP CG + E
Sbjct: 442 PVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGDRTFYDPEPI 501
Query: 424 LC 425
LC
Sbjct: 502 LC 503
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.326 0.139 0.439
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,941,799
Number of Sequences: 37866
Number of extensions: 758977
Number of successful extensions: 2488
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 39
Number of HSP's successfully gapped in prelim test: 19
Number of HSP's that attempted gapping in prelim test: 2353
Number of HSP's gapped (non-prelim): 97
length of query: 426
length of database: 18,247,518
effective HSP length: 105
effective length of query: 321
effective length of database: 14,271,588
effective search space: 4581179748
effective search space used: 4581179748
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.