Guide to the Human Genome
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Search of human proteins with 153792110

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|153792110 HEG homolog 1 [Homo sapiens]
         (1381 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|153792110 HEG homolog 1 [Homo sapiens]                            2736   0.0  
gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]           134   8e-31
gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]           134   8e-31
gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]           134   8e-31
gi|239740898 PREDICTED: hypothetical protein [Homo sapiens]           134   8e-31
gi|239740777 PREDICTED: hypothetical protein [Homo sapiens]           134   8e-31
gi|239740724 PREDICTED: hypothetical protein [Homo sapiens]           134   8e-31
gi|239740674 PREDICTED: hypothetical protein [Homo sapiens]           134   8e-31
gi|239740645 PREDICTED: hypothetical protein [Homo sapiens]           134   8e-31
gi|239513940 PREDICTED: hypothetical protein [Homo sapiens]           134   8e-31
gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo ...   132   2e-30
gi|91982772 mucin 17 [Homo sapiens]                                   122   3e-27
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                       119   2e-26
gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ...   116   1e-25
gi|239754668 PREDICTED: mucin 12 [Homo sapiens]                       116   2e-25
gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]      107   8e-23
gi|161019170 mucin 5AC [Homo sapiens]                                 105   3e-22
gi|239758038 PREDICTED: mucin 3A, cell surface associated, parti...   105   3e-22
gi|239743291 PREDICTED: mucin 3A, intestinal [Homo sapiens]           105   4e-22
gi|151301154 mucin 6, gastric [Homo sapiens]                          104   7e-22
gi|89026265 PREDICTED: mucin 12 [Homo sapiens]                         97   1e-19
gi|167736355 mucin 4 isoform a [Homo sapiens]                          96   2e-19
gi|116284392 mucin 2 precursor [Homo sapiens]                          96   3e-19
gi|239749213 PREDICTED: mucin 3B, cell surface associated, parti...    96   3e-19
gi|239508973 PREDICTED: similar to Mucin-3A [Homo sapiens]             96   3e-19
gi|239758058 PREDICTED: similar to mucin, partial [Homo sapiens]       94   1e-18
gi|239752529 PREDICTED: similar to mucin [Homo sapiens]                93   2e-18
gi|83367077 mucin 16 [Homo sapiens]                                    92   4e-18
gi|239757995 PREDICTED: similar to hCG1747327, partial [Homo sap...    91   8e-18
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    91   8e-18

>gi|153792110 HEG homolog 1 [Homo sapiens]
          Length = 1381

 Score = 2736 bits (7092), Expect = 0.0
 Identities = 1381/1381 (100%), Positives = 1381/1381 (100%)

Query: 1    MASPRASRWPPPLLLLLLPLLLLPPAAPGTRDPPPSPARRALSLAPLAGAGLELQLERRP 60
            MASPRASRWPPPLLLLLLPLLLLPPAAPGTRDPPPSPARRALSLAPLAGAGLELQLERRP
Sbjct: 1    MASPRASRWPPPLLLLLLPLLLLPPAAPGTRDPPPSPARRALSLAPLAGAGLELQLERRP 60

Query: 61   EREPPPTPPRERRGPATPGPSYRAPEPGAATQRGPSGRAPRGGSADAAWKHWPESNTEAH 120
            EREPPPTPPRERRGPATPGPSYRAPEPGAATQRGPSGRAPRGGSADAAWKHWPESNTEAH
Sbjct: 61   EREPPPTPPRERRGPATPGPSYRAPEPGAATQRGPSGRAPRGGSADAAWKHWPESNTEAH 120

Query: 121  VENITFYQNQEDFSTVSSKEGVMVQTSGKSHAASDAPENLTLLAETADARGRSGSSSRTN 180
            VENITFYQNQEDFSTVSSKEGVMVQTSGKSHAASDAPENLTLLAETADARGRSGSSSRTN
Sbjct: 121  VENITFYQNQEDFSTVSSKEGVMVQTSGKSHAASDAPENLTLLAETADARGRSGSSSRTN 180

Query: 181  FTILPVGYSLEIATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTASEMGTERAM 240
            FTILPVGYSLEIATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTASEMGTERAM
Sbjct: 181  FTILPVGYSLEIATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTASEMGTERAM 240

Query: 241  GLSEEWTVHSQEATTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASSPLL 300
            GLSEEWTVHSQEATTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASSPLL
Sbjct: 241  GLSEEWTVHSQEATTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASSPLL 300

Query: 301  DLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVSKTEGFP 360
            DLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVSKTEGFP
Sbjct: 301  DLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVSKTEGFP 360

Query: 361  KDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQNDSPTFG 420
            KDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQNDSPTFG
Sbjct: 361  KDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQNDSPTFG 420

Query: 421  EHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADVTGSSASYPEGV 480
            EHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADVTGSSASYPEGV
Sbjct: 421  EHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADVTGSSASYPEGV 480

Query: 481  NASVLTQFSDSTVQSGGSHTALGDRSYSESSSTSSSESLNSSAPRGERSIAGISYGQVRG 540
            NASVLTQFSDSTVQSGGSHTALGDRSYSESSSTSSSESLNSSAPRGERSIAGISYGQVRG
Sbjct: 481  NASVLTQFSDSTVQSGGSHTALGDRSYSESSSTSSSESLNSSAPRGERSIAGISYGQVRG 540

Query: 541  TAIEQRTSSDHTDHTYLSSTFTKGERALLSITDNSSSSDIVESSTSYIKISNSSHSEYSS 600
            TAIEQRTSSDHTDHTYLSSTFTKGERALLSITDNSSSSDIVESSTSYIKISNSSHSEYSS
Sbjct: 541  TAIEQRTSSDHTDHTYLSSTFTKGERALLSITDNSSSSDIVESSTSYIKISNSSHSEYSS 600

Query: 601  FFHAQTERSNISSYDGEYAQPSTESPVLHTSNLPSYTPTINMPNTSVVLDTDAEFVSDSS 660
            FFHAQTERSNISSYDGEYAQPSTESPVLHTSNLPSYTPTINMPNTSVVLDTDAEFVSDSS
Sbjct: 601  FFHAQTERSNISSYDGEYAQPSTESPVLHTSNLPSYTPTINMPNTSVVLDTDAEFVSDSS 660

Query: 661  SSSSSSSSSSSSGPPLPLPSVSQSHHLFSSILPSTRASVHLLKSTSDASTPWSSSPSPLP 720
            SSSSSSSSSSSSGPPLPLPSVSQSHHLFSSILPSTRASVHLLKSTSDASTPWSSSPSPLP
Sbjct: 661  SSSSSSSSSSSSGPPLPLPSVSQSHHLFSSILPSTRASVHLLKSTSDASTPWSSSPSPLP 720

Query: 721  VSLTTSTSAPLSVSQTTLPQSSSTPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADLKS 780
            VSLTTSTSAPLSVSQTTLPQSSSTPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADLKS
Sbjct: 721  VSLTTSTSAPLSVSQTTLPQSSSTPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADLKS 780

Query: 781  QSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESSTEQTLPATSTNLAQMSP 840
            QSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESSTEQTLPATSTNLAQMSP
Sbjct: 781  QSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESSTEQTLPATSTNLAQMSP 840

Query: 841  TFTTTILKTSQPLMTTPGTLSSTASLVTGPIAVQTTAGKQLSLTHPEILVPQISTEGGIS 900
            TFTTTILKTSQPLMTTPGTLSSTASLVTGPIAVQTTAGKQLSLTHPEILVPQISTEGGIS
Sbjct: 841  TFTTTILKTSQPLMTTPGTLSSTASLVTGPIAVQTTAGKQLSLTHPEILVPQISTEGGIS 900

Query: 901  TERNRVIVDATTGLIPLTSVPTSAKEMTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAED 960
            TERNRVIVDATTGLIPLTSVPTSAKEMTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAED
Sbjct: 901  TERNRVIVDATTGLIPLTSVPTSAKEMTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAED 960

Query: 961  LAPKSATFAVQSSTQSPTTVSSSASVNSCAVNPCLHNGECVADNTSRGYHCRCPPSWQGD 1020
            LAPKSATFAVQSSTQSPTTVSSSASVNSCAVNPCLHNGECVADNTSRGYHCRCPPSWQGD
Sbjct: 961  LAPKSATFAVQSSTQSPTTVSSSASVNSCAVNPCLHNGECVADNTSRGYHCRCPPSWQGD 1020

Query: 1021 DCSVDVNECLSNPCPSTAMCNNTQGSFICKCPVGYQLEKGICNLVRTFVTEFKLKRTFLN 1080
            DCSVDVNECLSNPCPSTAMCNNTQGSFICKCPVGYQLEKGICNLVRTFVTEFKLKRTFLN
Sbjct: 1021 DCSVDVNECLSNPCPSTAMCNNTQGSFICKCPVGYQLEKGICNLVRTFVTEFKLKRTFLN 1080

Query: 1081 TTVEKHSDLQEVENEITKTLNMCFSALPSYIRSTVHASRESNAVVISLQTTFSLASNVTL 1140
            TTVEKHSDLQEVENEITKTLNMCFSALPSYIRSTVHASRESNAVVISLQTTFSLASNVTL
Sbjct: 1081 TTVEKHSDLQEVENEITKTLNMCFSALPSYIRSTVHASRESNAVVISLQTTFSLASNVTL 1140

Query: 1141 FDLADRMQKCVNSCKSSAEVCQLLGSQRRIFRAGSLCKRKSPECDKDTSICTDLDGVALC 1200
            FDLADRMQKCVNSCKSSAEVCQLLGSQRRIFRAGSLCKRKSPECDKDTSICTDLDGVALC
Sbjct: 1141 FDLADRMQKCVNSCKSSAEVCQLLGSQRRIFRAGSLCKRKSPECDKDTSICTDLDGVALC 1200

Query: 1201 QCKSGYFQFNKMDHSCRACEDGYRLENETCMSCPFGLGGLNCGNPYQLITVVIAAAGGGL 1260
            QCKSGYFQFNKMDHSCRACEDGYRLENETCMSCPFGLGGLNCGNPYQLITVVIAAAGGGL
Sbjct: 1201 QCKSGYFQFNKMDHSCRACEDGYRLENETCMSCPFGLGGLNCGNPYQLITVVIAAAGGGL 1260

Query: 1261 LLILGIALIVTCCRKNKNDISKLIFKSGDFQMSPYAEYPKNPRSQEWGREAIEMHENGST 1320
            LLILGIALIVTCCRKNKNDISKLIFKSGDFQMSPYAEYPKNPRSQEWGREAIEMHENGST
Sbjct: 1261 LLILGIALIVTCCRKNKNDISKLIFKSGDFQMSPYAEYPKNPRSQEWGREAIEMHENGST 1320

Query: 1321 KNLLQMTDVYYSPTSVRNPELERNGLYPAYTGLPGSRHSCIFPGQYNPSFISDESRRRDY 1380
            KNLLQMTDVYYSPTSVRNPELERNGLYPAYTGLPGSRHSCIFPGQYNPSFISDESRRRDY
Sbjct: 1321 KNLLQMTDVYYSPTSVRNPELERNGLYPAYTGLPGSRHSCIFPGQYNPSFISDESRRRDY 1380

Query: 1381 F 1381
            F
Sbjct: 1381 F 1381


>gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score =  134 bits (336), Expect = 8e-31
 Identities = 217/904 (24%), Positives = 370/904 (40%), Gaps = 98/904 (10%)

Query: 134 STVSSKEGVMVQTSGKSHAASDAPENLTLLAETAD----ARGRSGSSSRTNFTILPVGYS 189
           ++ +S E  +  T+G          + T  A TAD    A   +GS   T FT      +
Sbjct: 127 NSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETIT 186

Query: 190 LEIATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTASEMGTERAMGLSEEWTVH 249
              A + T+      SE+  + ++ SE      A  +++  AS MG+E     ++  T  
Sbjct: 187 PSTAGSETTTVSTAGSETTTVSTTGSETTTASTA-HSETTAASTMGSE----TTKVSTAG 241

Query: 250 SQEATTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASS----PLLDLSSS 305
           S+   ++A S +   + E  E T  +   +S     S   F  TAAS+    P +  +  
Sbjct: 242 SETTVSTAGSETTAASTEDSE-TNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMG 300

Query: 306 SESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVSKTEGFPKDSRI 365
           SE+T  + ++ G +++ VS T +  V TVF   G  T+R+ TV  G  + T      +  
Sbjct: 301 SETT--MASTIGPETTKVS-TASSEVTTVFA-AGSETIRASTV--GSETTT---VSTTGS 351

Query: 366 ATTSSSVLLSPSAVESRRNSR-VTGNPGDEEFIEPSTENEFGLTSLRWQNDSPTFGEHQL 424
            TT++S++ S ++ +S   S   T +    E    STE     T     +++ T      
Sbjct: 352 ETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDS 411

Query: 425 ASSSEVQNGSPMSQTETV--SRSVAPMRGGEITAHWLLTNSTTSADVTGSSASYPEGVNA 482
            +++    GS M+   T     + A   G EIT      + TT+A   GS  +      +
Sbjct: 412 ETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGS 471

Query: 483 SVLTQFSDSTVQSGGSHTALGDR------SYSESSSTSSSESLNSSAPRGER---SIAGI 533
              T ++  +  +  S+T L         S + ++ST  SE+   SA   E    S  G 
Sbjct: 472 ETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGS 531

Query: 534 SYGQVRGTAIEQRTSSDHTDHTYLSSTFTKG-ERALLSITDNSSSSDIVESSTSYIKISN 592
               V  T  E  T S  T     ++T T+G E   +S T   +++D  E S +    ++
Sbjct: 532 ENTTVSTTGSETTTVS--TTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGT--TAAS 587

Query: 593 SSHSEYSSFFHAQTERSNISSYDGEYAQPST---ESPVLHTSNLPSYTPTINMPNTSVVL 649
           ++ SE ++   A +E +  S+ D E    ST   E+    T++  + T +     T+ V 
Sbjct: 588 TAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVS 647

Query: 650 DTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSILPSTRASVHLLKSTSDAS 709
            TD+E    S++ S  + +S+       + +      + +    +T  S+     T   +
Sbjct: 648 TTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSI-----TGSET 702

Query: 710 TPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQSSSTPVLPRARETPVTSFQTSTMTSFMTM 769
           T  S++ S      TT+++    ++  ++  S +T       ET   S + S  TS  T 
Sbjct: 703 TKVSTTGS----ETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTT 758

Query: 770 LHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESST----- 824
              + TA   S  T     + +E+   S +   +E+TK  T +S +    TE+S      
Sbjct: 759 GSETTTASTTSSETTMASIMGSETTMASTIG--SETTKVSTASSKMTTVFTENSETTIAS 816

Query: 825 -------------EQTLPATSTNLAQMSPTFTTTILKTSQ-PLMTTPGTLSSTASLVTGP 870
                         +T+PA++      S T TTT  + S+    +T G+ ++TAS  +  
Sbjct: 817 TTASETTTVSTAGSETIPASTAG----SETTTTTSTEGSETTTASTEGSETTTASTESSE 872

Query: 871 IAVQTTAGKQLSLTHPEILVPQISTEGG----ISTERNRVIVDATTGLIPLTSVPTSAKE 926
               TT G + +           STEG      STE +     +T G   +T+V T+  E
Sbjct: 873 TTTATTIGSETTTA---------STEGSETTTTSTEGSETTTASTEG-SEITTVSTTGSE 922

Query: 927 MTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSATFAVQSSTQSPTTVSSSASV 986
            TT     +E + AS    T  S  TTV +T  +    SA     S T + TT+ S  + 
Sbjct: 923 TTTASTEGSETTTAS----TEGSELTTVSTTGSETITVSAE---GSETTTVTTMGSETTT 975

Query: 987 NSCA 990
            S A
Sbjct: 976 ASTA 979



 Score =  128 bits (321), Expect = 4e-29
 Identities = 209/911 (22%), Positives = 353/911 (38%), Gaps = 84/911 (9%)

Query: 114  ESNTEAHVENITFYQNQEDFSTVSSKEGVMVQTSGKSHAASDAPENLTLLAETADARGRS 173
            +S T +     +   ++   ++    E   V T+G         ++ T    T  +   +
Sbjct: 366  DSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTA 425

Query: 174  GSSSRTNFTILPV-GYSLEIATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTAS 232
             S++    T     G  + IA+   S++   ++E     + ++   E   A+ T S T +
Sbjct: 426  VSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTT 485

Query: 233  EMGTERAMGLSEEWTVHSQEATTSAWSPSFLPALEMG-ELTTPSRKRNSSGPDLSWLHFY 291
               T   +  +  +T+ S   T S            G E+TT S + + +    +     
Sbjct: 486  ASNT--GLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSET 543

Query: 292  RTAASSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLG 351
             T +++ L   ++S+E +E    ST    ++   T+        T G   T    TVS  
Sbjct: 544  TTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETT----TVSTA 599

Query: 352  PVSKTEGFPKDSRIATTSSSVLLSPSAVESRRNSRVT--GNPGDEEFIEPSTENEFGLTS 409
                T     DS   TTS+S   S +   S  +S  T     G E     +T++E  + S
Sbjct: 600  DSENTTASTADSE--TTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVS 657

Query: 410  LRWQNDSPTFGEHQLASSSEVQNGSPMSQT---ETVSRSVAPMRGGEITAHWLLTNSTTS 466
                    T G  +  +S+E    + +S T    TVS   +      IT       STT 
Sbjct: 658  --------TTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTG 709

Query: 467  ADVTGSSASYPEGVNASVLTQFSDSTVQSGGSHTALGDRSYSE--SSSTSSSESLNSSAP 524
            ++ T +S    E   AS+ T    +T  + GS T       SE  S+ST+ SE+  +S  
Sbjct: 710  SETTTTSTEGSEITTASI-TGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTT 768

Query: 525  RGERSIAGISYGQVR-GTAIEQRTSSDHTDHTYLSSTFTKGERALLSITDNSSSSDIVES 583
              E ++A I   +    + I   T+   T  + +++ FT+     ++ T  S ++ +  +
Sbjct: 769  SSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTA 828

Query: 584  STSYIKISNSSHSEYSSFFHAQTERSNISSYDGEYAQPSTESPVLHTSNLPSYTPTINMP 643
             +  I  S +     ++     +E +  S+   E    STES    T+       TI   
Sbjct: 829  GSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTAT------TIGSE 882

Query: 644  NTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSI------LPSTRA 697
             T+    T+    + +S+  S ++++S+ G  +   S + S    +S         ST  
Sbjct: 883  TTTA--STEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEG 940

Query: 698  SVHLLKSTSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQSSSTPVLPRARETPVTS 757
            S     ST+ + T   S+      ++TT  S   + S      S +T V     ET   S
Sbjct: 941  SELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAG---SETTTVSTAGSETTTAS 997

Query: 758  FQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPT---ESTKAVTTNSP 814
             + S  T+      SS  ++  + ST   E  IT ++     ++ T   E+T   TT S 
Sbjct: 998  IEGSETTTV-----SSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSE 1052

Query: 815  LPPSLTESSTEQTLPATSTNLAQMSPT-FTTTILKTSQPLMTTPGTLSSTASLVTGPIAV 873
               + TE S   T+  T +     S     TT + TS    TT  T  S  + V    + 
Sbjct: 1053 TTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSK 1112

Query: 874  QTTAGKQLSLTHPEILVPQISTEGG----ISTERNRVIVDATTGLIPLTSVPTSAKEMTT 929
             TTA                STEG     +ST  +     +TTG   +T+V T+  E TT
Sbjct: 1113 TTTA----------------STEGSEATTVSTTSSETTTASTTG-SEMTTVFTTVSETTT 1155

Query: 930  --KLGVTAEYSPASRSLGTSPS---PQTTVVSTAEDLAPKSATFAVQSSTQS-----PTT 979
               +G  A  S A+ S  T+ S    +TT  STA      ++T   +++T S      TT
Sbjct: 1156 VSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTAGSETTT 1215

Query: 980  VSSSASVNSCA 990
             S+S S  + A
Sbjct: 1216 ASTSGSETNTA 1226



 Score =  118 bits (296), Expect = 3e-26
 Identities = 200/902 (22%), Positives = 348/902 (38%), Gaps = 74/902 (8%)

Query: 134  STVSSKEGVMVQTSG-KSHAASDAPENLTLLAETADARGRSGSSSRTNFTILPVGYSLEI 192
            ST+ S E  M  T G ++   S A   +T +        R+ +      T+   G     
Sbjct: 297  STMGS-ETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTT 355

Query: 193  ATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTASEMGTERAMGLSEEWTVH--S 250
            A+ + S++   ++      ++S+E  E   A    S   SE  T    G SE  TV    
Sbjct: 356  ASIMGSETSTDSTTGSETTTASTEGSETTTA----STEGSEATTVSTTG-SETTTVSITD 410

Query: 251  QEATTSAWSPSFLPAL------------EMGELT---TPSRKRNSSGPDLSWLHFYRTAA 295
             E TT+    S + A+            E  E+T   T   +  ++  + S      TA 
Sbjct: 411  SETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAG 470

Query: 296  SSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVSK 355
            S      ++ SE+T   N  TGL++++V  T      T  T+G   T  S T S      
Sbjct: 471  SETKTAYTTGSETTTASN--TGLETTTVF-TIGSDTTTASTEGSETTAVSATGSEMTTVS 527

Query: 356  TEGFPKDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQND 415
            TEG    +   T S +  +S + +E+   S         E  E +T +  G  +     +
Sbjct: 528  TEGSENTTVSTTGSETTTVSTTGLETTTTST--------EGSEMTTVSTTGAETTTDSTE 579

Query: 416  SPTFGEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADVTGSSAS 475
                     A S      +  S+  T S + +       T     T STTS++ T +S  
Sbjct: 580  GSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTE 639

Query: 476  YPEGVNASVLTQFSDSTVQSGGSHTALGDRSYSESSSTSSSESLNSSAPRGER----SIA 531
              E    S  T    + V + GS   +     SE+++ S++ S  + +  G      SI 
Sbjct: 640  GSETTTVST-TDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSIT 698

Query: 532  GISYGQVRGTAIEQRTSSDHTDHTYLSS--------TFTKGERALLSITDNS--SSSDIV 581
            G    +V  T  E  T+S        +S          T+G     + T+ S  +S+   
Sbjct: 699  GSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTT 758

Query: 582  ESSTSYIKISNSSHSEYSSFFHAQTERSNISSYDGEYAQPSTESPVLHTSNLPSYTPTIN 641
             S T+    ++S  +  S      T  S I S   + +  S++   + T N  +   +  
Sbjct: 759  GSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTT 818

Query: 642  MPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSILPS-TRASVH 700
               T+ V    +E +  S++ S +++++S+ G      S   S    +S   S T  +  
Sbjct: 819  ASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATT 878

Query: 701  LLKSTSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQ--SSSTPVLPRARETPVTSF 758
            +   T+ AST  S + +       T+T++      TT+    S +T       ET   S 
Sbjct: 879  IGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAST 938

Query: 759  QTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPS 818
            + S +T+  T    S+T  + ++ +         S++ +  +  +E+T   T  S    +
Sbjct: 939  EGSELTTVSTT--GSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTA 996

Query: 819  LTESSTEQTLPATSTNLAQMSPTFTTTILKTSQPLMTTPGTLSSTASLVTGPIAVQTTAG 878
              E S   T+ +T +    +S T T T + +++   TT  T+++  S  T   AV TT  
Sbjct: 997  SIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETT--TVTTAGSETT---AVYTTGS 1051

Query: 879  KQLSLTHPEILVPQISTEGGISTERNRVIVDATTGLIP---LTSVPTSAKEMTTKLGVTA 935
            +  + +        +ST G  +T  +   ++ TT        T+  T+  E TT     +
Sbjct: 1052 ETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGS 1111

Query: 936  EYSPASRSLGTSPSPQTTVVSTAEDLAPKSAT-------FAVQSSTQSPTTVSSSASVNS 988
            + + AS    T  S  TTV +T+ +    S T       F   S T + +T+ S A+ +S
Sbjct: 1112 KTTTAS----TEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSS 1167

Query: 989  CA 990
             A
Sbjct: 1168 AA 1169



 Score =  105 bits (261), Expect = 4e-22
 Identities = 191/857 (22%), Positives = 342/857 (39%), Gaps = 147/857 (17%)

Query: 230 TASEMGTERAMGLSEEWTVHSQEATTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLH 289
           TAS  G+E    L     + + E TT++ + S        E TTPS       P  S   
Sbjct: 17  TASTTGSETTTIL-----IKASETTTASTAGS--------ETTTPS-------PTGSQTT 56

Query: 290 FYRTAASSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVS 349
               + S      ++ SE+T   +  +G  ++S++ ++T    TV T G   T  S+T +
Sbjct: 57  IVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSET----TVSTAGSETTTVSITGT 112

Query: 350 LGPVSKTEGFPKDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTS 409
              +    G    +   T+S + + S +  E+   S V    G E     + ++E    S
Sbjct: 113 ETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTV----GSETTTAYTADSETTAAS 168

Query: 410 LRWQNDSPTFGEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADV 469
                 +  F     A S  +   +  S+T TVS +     G E T     T STT ++ 
Sbjct: 169 TTGSEMTTVF----TAGSETITPSTAGSETTTVSTA-----GSETT-----TVSTTGSET 214

Query: 470 TGSSASYPEGVNAS--------VLTQFSDSTVQSGGS------------HTALGDRSYSE 509
           T +S ++ E   AS        V T  S++TV + GS            +TA  + S + 
Sbjct: 215 TTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTT 274

Query: 510 SSSTSSSESLNSSAPRGERSIAGISYGQ-VRGTAIEQRTSSDHTDHTYLSSTFTKGERAL 568
           ++ST+  E+  +S    E ++A     +    + I   T+   T  + +++ F  G   +
Sbjct: 275 TASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETI 334

Query: 569 LSITDNSSSSDIVESSTSYIKISNSSHSEYSSFFHAQTERSNISSYDGEYAQPSTE-SPV 627
            + T  S ++  V ++ S    ++   SE S+     +E +  S+   E    STE S  
Sbjct: 335 RASTVGSETT-TVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEA 393

Query: 628 LHTSNLPSYTPTINMPNT---------------------SVVLDTDAEFVSDSSSSSSSS 666
              S   S T T+++ ++                     +    T+   ++ +S+S S +
Sbjct: 394 TTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSET 453

Query: 667 SSSSSSGPPLPLPSV--SQSHHLFSSILPSTRASVHLLKST------SDASTPWSSSPSP 718
           +++S+ G      +   S++   +++   +T AS   L++T      SD +T  +     
Sbjct: 454 TTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSET 513

Query: 719 LPVSLTTSTSAPLSV---SQTTLPQ--SSSTPVLPRARETPVTSFQTSTMTSFMT----- 768
             VS T S    +S      TT+    S +T V     ET  TS + S MT+  T     
Sbjct: 514 TAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAET 573

Query: 769 -------------MLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPL 815
                            S+T  + +  + +      +S++ S  +  +E+T A TT+S  
Sbjct: 574 TTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSET 633

Query: 816 PPSLTESSTEQTLPATSTNLAQMSPT------------FTTTILKT-SQPLMTTPGTLSS 862
             + TE S   T+  T +    +S T             TTT+  T S+  ++T G+ ++
Sbjct: 634 TTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTT 693

Query: 863 TASLVTGPIAVQTTAGKQLSLTH---PEILVPQI--------STEGG----ISTERNRVI 907
           T S+        +T G + + T     EI    I        STEG      STE +   
Sbjct: 694 TVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETT 753

Query: 908 VDATTGLIPLTSVPTSAKEMTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSAT 967
             +TTG    T+  TS++  TT   +    +  + ++G+  +  +T  S    +  +++ 
Sbjct: 754 SASTTGSETTTASTTSSE--TTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSE 811

Query: 968 FAVQSSTQSPTTVSSSA 984
             + S+T S TT  S+A
Sbjct: 812 TTIASTTASETTTVSTA 828



 Score = 97.4 bits (241), Expect = 8e-20
 Identities = 205/912 (22%), Positives = 341/912 (37%), Gaps = 105/912 (11%)

Query: 121  VENITFYQNQEDFSTVSSK--EGVMVQTSGKSHAASDAPENLTLLAETADARGRSGSSSR 178
            +E  T      + +TVS+   E     T G    A+    + T    TAD+   + S++ 
Sbjct: 551  LETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTAD 610

Query: 179  TNFTILPVGYSLEIATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTA--SEMGT 236
            +  T          A+   S++   ++ S    ++S+E  E      T S T   S  G+
Sbjct: 611  SETTS---------ASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGS 661

Query: 237  ERAMGLSEEWTVHSQEATTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAAS 296
            ER +  +E       E TT + + S       G  TT      S    +S      T  S
Sbjct: 662  ERTITSTE-----GSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTS 716

Query: 297  SPLLDLSSSS-ESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVSK 355
            +   +++++S   +E    ST    ++ + T+     +  T G   T  S T S   ++ 
Sbjct: 717  TEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMAS 776

Query: 356  TEGFPKDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQND 415
              G   ++ +A+T  S     S   S+  +  T N   E  I  +T +E    S      
Sbjct: 777  IMG--SETTMASTIGSETTKVSTASSKMTTVFTEN--SETTIASTTASETTTVS------ 826

Query: 416  SPTFGEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADVTGSSAS 475
              T G   + +S+     +  + TE    + A   G E T     T ST S++ T ++  
Sbjct: 827  --TAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETT-----TASTESSETTTATTI 879

Query: 476  YPEGVNASVLTQFSDSTVQSG-GSHTALGDRSYSESS--STSSSESLNSSAPRGERSIAG 532
              E   AS  T+ S++T  S  GS T       SE +  ST+ SE+  +S    E + A 
Sbjct: 880  GSETTTAS--TEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAS 937

Query: 533  ISYGQVRGTAIEQRTSSDHTDHTYLSSTFTKGERALLSITDNSSSSDIVESSTSYIKISN 592
                ++  T +    S   T     S T T       + T +++ S+    ST+  + + 
Sbjct: 938  TEGSEL--TTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTT 995

Query: 593  SS--HSEYSSFFHAQTERSNISSYDGEYAQPSTESPVLHTSNLPSYTPTINMPNTSVVLD 650
            +S   SE ++     +E + +S+   E    STE     T        T      S    
Sbjct: 996  ASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTT 1055

Query: 651  TDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHH--LFSSILPSTRASVHLLKS-TSD 707
            T  E    ++ S++ S ++++S   L   +VS S      +S   S   +V++  S T+ 
Sbjct: 1056 TSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTT 1115

Query: 708  ASTPWSSSPSPLPVSLTTSTSAPLSVSQTTL--PQSSSTPVLPRARETPVTSFQTSTMTS 765
            AST  S + +    S  T+T++      TT+    S +T V     E   +S   S  T+
Sbjct: 1116 ASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATT 1175

Query: 766  FMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESSTE 825
              T    + TA      T       +E+ + S     +E+T A T+ S    + T  S  
Sbjct: 1176 TSTEGSETTTASTAGSETTTASTAGSETTTASTAG--SETTTASTSGSETNTACTTGSET 1233

Query: 826  QT---------------LPATSTNLAQMSPTF-------TTTILKTSQPLMTTPGTLSST 863
             T                  T  + A + PT        TTT+  T+        T+SST
Sbjct: 1234 STPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSST 1293

Query: 864  ASLVT------------GPIAVQTTAGKQLSLTHPEILVPQISTEGGISTERNRVIVDAT 911
              ++T             P++   T G +L+ +    + P +      ++     IV  T
Sbjct: 1294 TFVLTKATDVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMDFTASAASHTVPGIVLNT 1353

Query: 912  TGLIPLT---SVPTSAKEMTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSATF 968
            +GL   T   S  TSA  + T  G T E  P S              ST ++  P S   
Sbjct: 1354 SGLGTSTMGASSTTSAHGVRTTTGSTRE--PTS--------------STFQETGPVSMGT 1397

Query: 969  AVQSSTQSPTTV 980
               S + +PT V
Sbjct: 1398 NTVSMSHTPTNV 1409



 Score = 93.6 bits (231), Expect = 1e-18
 Identities = 138/603 (22%), Positives = 237/603 (39%), Gaps = 69/603 (11%)

Query: 445 SVAPMRGGEITAHWLLTNSTTSADVTGSSASYPE---------GVNASVLTQFS-----D 490
           + A   G E T   +  + TT+A   GS  + P           ++ S +T  S     +
Sbjct: 16  TTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSEN 75

Query: 491 STVQSGGSHTALGDRSYSESS-STSSSESLNSSAPRGERSIAGISYGQVRGTAIEQRTSS 549
           +TV S GS T     + SE++ ST+ SE+          SI G     V     E  T+S
Sbjct: 76  TTVSSAGSGTTTASMAGSETTVSTAGSETTTV-------SITGTETTMVSAMGSETTTNS 128

Query: 550 DHTDHTYLSSTFTKGERALLSITDNSSSSDIVESSTSYIKISNSSHSEYSSFFHAQTERS 609
             +  T ++ST       + ++   ++++   +S T+    ++++ SE ++ F A +E  
Sbjct: 129 TTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETT---AASTTGSEMTTVFTAGSETI 185

Query: 610 NISSYDGEYAQPST---ESPVLHTSNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSS 666
             S+   E    ST   E+  + T+   + T +     T+      +E    S++ S ++
Sbjct: 186 TPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETT 245

Query: 667 SSSSSSGPPLPLPSVSQSHHLFSSILPSTRASVHLLKSTSDASTPWSSSPSPLPVSLTTS 726
            S++ S         S+++  F+    +T AS    ++T+ AST  S       +   T+
Sbjct: 246 VSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTA-ASTTGSEPTMASTMGSETT 304

Query: 727 TSAPLSVSQTTLPQSSS--TPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADL-----K 779
            ++ +    T +  +SS  T V     ET   S   S  T+  T    + TA +      
Sbjct: 305 MASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETS 364

Query: 780 SQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESSTEQTLPATSTNLAQMS 839
           + ST   E     ++     +  TE ++A T ++    + T S T+     T T  ++M+
Sbjct: 365 TDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMT 424

Query: 840 PTFTT--------------TILKTSQPLMTTPGTLSSTASLVT----GPIAVQTTAGKQL 881
              TT              TI  TS    TT  T  S  + VT          TT  +  
Sbjct: 425 AVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETT 484

Query: 882 SLTHPEILVPQISTEGG----ISTERNRVIVDATTGLIPLTSVPTSAKEMTTKLGVTAEY 937
           + ++  +    + T G      STE +     + TG   +T+V T   E TT     +E 
Sbjct: 485 TASNTGLETTTVFTIGSDTTTASTEGSETTAVSATG-SEMTTVSTEGSENTTVSTTGSET 543

Query: 938 SPAS------RSLGTSPSPQTTV----VSTAEDLAPKSATFAVQSSTQSPTTVSSSASVN 987
           +  S       +  T  S  TTV      T  D    S T A  ++    TTVS++ S N
Sbjct: 544 TTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSEN 603

Query: 988 SCA 990
           + A
Sbjct: 604 TTA 606



 Score = 63.9 bits (154), Expect = 1e-09
 Identities = 137/617 (22%), Positives = 220/617 (35%), Gaps = 62/617 (10%)

Query: 46   PLAGAGLELQLERRPEREPPPTPPRERRGPATPGPSYRAPEPGAATQRGP-SGRAPRGGS 104
            P + AG E       E     T   E  G  T   S  + E   AT  G  +  A   GS
Sbjct: 834  PASTAGSETTTTTSTEGSETTTASTE--GSETTTASTESSETTTATTIGSETTTASTEGS 891

Query: 105  ADAAWKHWPESNTEAHVEN--ITFYQNQEDFSTVSSKEGVMVQTSGKSHAASDAPENLTL 162
                        T A  E   IT        +T +S EG    T      AS     LT 
Sbjct: 892  ETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTT------ASTEGSELTT 945

Query: 163  LAETADARGRSGSSSRTNFTILPVGYSLEIATALTSQSGNLASESLHLPSSSSEFDERIA 222
            ++ T        +      T+  +G     A+   S++  +++      ++S E  E   
Sbjct: 946  VSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTT 1005

Query: 223  AFQTKSGTA--SEMGTERAMGLSEEWTVHSQEATTSAWSPSFLPAL-EMGELTTPSRKRN 279
               T S T   S  GTE  +  +E       E TT   + S   A+   G  TT +    
Sbjct: 1006 VSSTGSETTTVSTTGTETTITSTE-----GSETTTVTTAGSETTAVYTTGSETTTTSTEG 1060

Query: 280  SSGPDLSWLHFYRTAASSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVA-----TV 334
            S    +S      T AS+   DL +++ ST     +T   S++ S+T T+++      T 
Sbjct: 1061 SETTTVSTTGSETTTASTA--DLETTTVSTSGSGTTTA--STAGSETTTVYITGSKTTTA 1116

Query: 335  FTDGGPRTLRSLTVSLGPVSKTEGFPKDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDE 394
             T+G   T  S T S    + T G    +   T S +  +S    E+      T +    
Sbjct: 1117 STEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEA-----TTSSAAGS 1171

Query: 395  EFIEPSTENEFGLTSLRWQNDSPTFGEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEI 454
            E    STE     T+               A S      +  S+T T S +     G E 
Sbjct: 1172 EATTTSTEGSETTTA-------------STAGSETTTASTAGSETTTASTA-----GSET 1213

Query: 455  TAHWLLTNSTTSADVTGSSASYPEGVNASVLTQFSDSTVQSGGSHTALGDRSYSESSSTS 514
            T      + T +A  TGS  S P    +   T F   +  +  S  +L   + S + S +
Sbjct: 1214 TTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSET 1273

Query: 515  SSESLNSS-APRGERSIAGISYGQVRGTAIEQRTSSDHTDHTYLSSTFTKGERALLSIT- 572
            ++ S+ +S A     +++  ++   + T +    S     +T +S T T G R   S + 
Sbjct: 1274 TTVSITASGATAASTTVSSTTFVLTKATDV----SIQPITNTPMSGTRTTGTRLTASSSV 1329

Query: 573  DNSSSSDIVESSTSY----IKISNSSHSEYSSFFHAQTERSNISSYDGEYAQPSTESPVL 628
              +   D   S+ S+    I ++ S     +    + T    + +  G   +P T S   
Sbjct: 1330 TMAPGMDFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGSTREP-TSSTFQ 1388

Query: 629  HTSNLPSYTPTINMPNT 645
             T  +   T T++M +T
Sbjct: 1389 ETGPVSMGTNTVSMSHT 1405



 Score = 61.2 bits (147), Expect = 6e-09
 Identities = 106/542 (19%), Positives = 202/542 (37%), Gaps = 41/542 (7%)

Query: 644  NTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSILPSTRASVHLLK 703
            NT+    T +E  +     +S ++++S++G     PS + S    ++I+  + + +    
Sbjct: 14   NTTTASTTGSE-TTTILIKASETTTASTAGSETTTPSPTGSQ---TTIVSISGSEITTTS 69

Query: 704  STSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQSSSTPVLPRARETPVTSFQTSTM 763
            +    +T  SS+ S      TT++ A    + +T    ++T  +     T V++  + T 
Sbjct: 70   TAGSENTTVSSAGS----GTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETT 125

Query: 764  TSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESS 823
            T+  T   ++ T+   S++T         S++ +  +  +E+T A TT S +    T  S
Sbjct: 126  TNSTTSSETTVTSTAGSETTTVS---TVGSETTTAYTADSETTAASTTGSEMTTVFTAGS 182

Query: 824  TEQTLPATSTNLAQMSPTFTTTILKTSQPLMTTPGTLSSTASLVTGPIAVQTTAGKQLSL 883
             E   P+T+      S T T +   +    ++T G+ ++TAS         +T G + + 
Sbjct: 183  -ETITPSTAG-----SETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTK 236

Query: 884  THPEILVPQISTEGGIST-------ERNRVIV-DATTGLIPLTSVPTSAKEMTTKLGVTA 935
                     +ST G  +T       E N     D+ T     T   T+A   T      A
Sbjct: 237  VSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMA 296

Query: 936  EYSPASRSLGTSPSPQTTVVSTAED-----LAPKSATFAVQSSTQSPTTVSSSASVNSCA 990
                +  ++ ++  P+TT VSTA        A  S T    +     TTVS++ S  + A
Sbjct: 297  STMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTA 356

Query: 991  VNPCLHNGECVADNTSRGYHCRCPPSWQGDDCSVDVNE-----CLSNPCPSTAMCNNTQG 1045
                +   E   D+T+         S +G + +    E      +S     T   + T  
Sbjct: 357  ---SIMGSETSTDSTTGSE--TTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDS 411

Query: 1046 SFICKCPVGYQLEKGICNLVRTFVTEFKLKRTFLNTTVEKHSDLQEVENEITKTLNMCFS 1105
                 C  G ++      +  T     +     + +T +  +     E   T T+    S
Sbjct: 412  ETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGS 471

Query: 1106 ALPSYIRSTVHASRESNAVVISLQTTFSLASNVTLFDLADRMQKCVNSCKSSAEVCQLLG 1165
               +   +    +  SN   +   T F++ S+ T           V++  S        G
Sbjct: 472  ETKTAYTTGSETTTASN-TGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEG 530

Query: 1166 SQ 1167
            S+
Sbjct: 531  SE 532


>gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1521

 Score =  134 bits (336), Expect = 8e-31
 Identities = 217/904 (24%), Positives = 370/904 (40%), Gaps = 98/904 (10%)

Query: 134 STVSSKEGVMVQTSGKSHAASDAPENLTLLAETAD----ARGRSGSSSRTNFTILPVGYS 189
           ++ +S E  +  T+G          + T  A TAD    A   +GS   T FT      +
Sbjct: 127 NSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETIT 186

Query: 190 LEIATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTASEMGTERAMGLSEEWTVH 249
              A + T+      SE+  + ++ SE      A  +++  AS MG+E     ++  T  
Sbjct: 187 PSTAGSETTTVSTAGSETTTVSTTGSETTTASTA-HSETTAASTMGSE----TTKVSTAG 241

Query: 250 SQEATTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASS----PLLDLSSS 305
           S+   ++A S +   + E  E T  +   +S     S   F  TAAS+    P +  +  
Sbjct: 242 SETTVSTAGSETTAASTEDSE-TNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMG 300

Query: 306 SESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVSKTEGFPKDSRI 365
           SE+T  + ++ G +++ VS T +  V TVF   G  T+R+ TV  G  + T      +  
Sbjct: 301 SETT--MASTIGPETTKVS-TASSEVTTVFA-AGSETIRASTV--GSETTT---VSTTGS 351

Query: 366 ATTSSSVLLSPSAVESRRNSR-VTGNPGDEEFIEPSTENEFGLTSLRWQNDSPTFGEHQL 424
            TT++S++ S ++ +S   S   T +    E    STE     T     +++ T      
Sbjct: 352 ETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDS 411

Query: 425 ASSSEVQNGSPMSQTETV--SRSVAPMRGGEITAHWLLTNSTTSADVTGSSASYPEGVNA 482
            +++    GS M+   T     + A   G EIT      + TT+A   GS  +      +
Sbjct: 412 ETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGS 471

Query: 483 SVLTQFSDSTVQSGGSHTALGDR------SYSESSSTSSSESLNSSAPRGER---SIAGI 533
              T ++  +  +  S+T L         S + ++ST  SE+   SA   E    S  G 
Sbjct: 472 ETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGS 531

Query: 534 SYGQVRGTAIEQRTSSDHTDHTYLSSTFTKG-ERALLSITDNSSSSDIVESSTSYIKISN 592
               V  T  E  T S  T     ++T T+G E   +S T   +++D  E S +    ++
Sbjct: 532 ENTTVSTTGSETTTVS--TTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGT--TAAS 587

Query: 593 SSHSEYSSFFHAQTERSNISSYDGEYAQPST---ESPVLHTSNLPSYTPTINMPNTSVVL 649
           ++ SE ++   A +E +  S+ D E    ST   E+    T++  + T +     T+ V 
Sbjct: 588 TAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVS 647

Query: 650 DTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSILPSTRASVHLLKSTSDAS 709
            TD+E    S++ S  + +S+       + +      + +    +T  S+     T   +
Sbjct: 648 TTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSI-----TGSET 702

Query: 710 TPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQSSSTPVLPRARETPVTSFQTSTMTSFMTM 769
           T  S++ S      TT+++    ++  ++  S +T       ET   S + S  TS  T 
Sbjct: 703 TKVSTTGS----ETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTT 758

Query: 770 LHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESST----- 824
              + TA   S  T     + +E+   S +   +E+TK  T +S +    TE+S      
Sbjct: 759 GSETTTASTTSSETTMASIMGSETTMASTIG--SETTKVSTASSKMTTVFTENSETTIAS 816

Query: 825 -------------EQTLPATSTNLAQMSPTFTTTILKTSQ-PLMTTPGTLSSTASLVTGP 870
                         +T+PA++      S T TTT  + S+    +T G+ ++TAS  +  
Sbjct: 817 TTASETTTVSTAGSETIPASTAG----SETTTTTSTEGSETTTASTEGSETTTASTESSE 872

Query: 871 IAVQTTAGKQLSLTHPEILVPQISTEGG----ISTERNRVIVDATTGLIPLTSVPTSAKE 926
               TT G + +           STEG      STE +     +T G   +T+V T+  E
Sbjct: 873 TTTATTIGSETTTA---------STEGSETTTTSTEGSETTTASTEG-SEITTVSTTGSE 922

Query: 927 MTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSATFAVQSSTQSPTTVSSSASV 986
            TT     +E + AS    T  S  TTV +T  +    SA     S T + TT+ S  + 
Sbjct: 923 TTTASTEGSETTTAS----TEGSELTTVSTTGSETITVSAE---GSETTTVTTMGSETTT 975

Query: 987 NSCA 990
            S A
Sbjct: 976 ASTA 979



 Score =  129 bits (323), Expect = 3e-29
 Identities = 202/902 (22%), Positives = 348/902 (38%), Gaps = 76/902 (8%)

Query: 114  ESNTEAHVENITFYQNQEDFSTVSSKEGVMVQTSGKSHAASDAPENLTLLAETADARGRS 173
            +S T +     +   ++   ++    E   V T+G         ++ T    T  +   +
Sbjct: 366  DSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTA 425

Query: 174  GSSSRTNFTILPV-GYSLEIATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTAS 232
             S++    T     G  + IA+   S++   ++E     + ++   E   A+ T S T +
Sbjct: 426  VSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTT 485

Query: 233  EMGTERAMGLSEEWTVHSQEATTSAWSPSFLPALEMG-ELTTPSRKRNSSGPDLSWLHFY 291
               T   +  +  +T+ S   T S            G E+TT S + + +    +     
Sbjct: 486  ASNT--GLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSET 543

Query: 292  RTAASSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLG 351
             T +++ L   ++S+E +E    ST    ++   T+        T G   T    TVS  
Sbjct: 544  TTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETT----TVSTA 599

Query: 352  PVSKTEGFPKDSRIATTSSSVLLSPSAVESRRNSRVT--GNPGDEEFIEPSTENEFGLTS 409
                T     DS   TTS+S   S +   S  +S  T     G E     +T++E  + S
Sbjct: 600  DSENTTASTADSE--TTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVS 657

Query: 410  LRWQNDSPTFGEHQLASSSEVQNGSPMSQT---ETVSRSVAPMRGGEITAHWLLTNSTTS 466
                    T G  +  +S+E    + +S T    TVS   +      IT       STT 
Sbjct: 658  --------TTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTG 709

Query: 467  ADVTGSSASYPEGVNASVLTQFSDSTVQSGGSHTALGDRSYSE--SSSTSSSESLNSSAP 524
            ++ T +S    E   AS+ T    +T  + GS T       SE  S+ST+ SE+  +S  
Sbjct: 710  SETTTTSTEGSEITTASI-TGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTT 768

Query: 525  RGERSIAGISYGQVR-GTAIEQRTSSDHTDHTYLSSTFTKGERALLSITDNSSSSDIVES 583
              E ++A I   +    + I   T+   T  + +++ FT+     ++ T  S ++ +  +
Sbjct: 769  SSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTA 828

Query: 584  STSYIKISNSSHSEYSSFFHAQTERSNISSYDGEYAQPSTESPVLHTSNLPSYTPTINMP 643
             +  I  S +     ++     +E +  S+   E    STES    T+       TI   
Sbjct: 829  GSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTAT------TIGSE 882

Query: 644  NTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSI------LPSTRA 697
             T+    T+    + +S+  S ++++S+ G  +   S + S    +S         ST  
Sbjct: 883  TTTA--STEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEG 940

Query: 698  SVHLLKSTSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQSSSTPVLPRARETPVTS 757
            S     ST+ + T   S+      ++TT  S   + S      S +T V     ET   S
Sbjct: 941  SELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAG---SETTTVSTAGSETTTAS 997

Query: 758  FQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPT---ESTKAVTTNSP 814
             + S  T+      SS  ++  + ST   E  IT ++     ++ T   E+T   TT S 
Sbjct: 998  IEGSETTTV-----SSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSE 1052

Query: 815  LPPSLTESSTEQTLPATSTNLAQMSPT-FTTTILKTSQPLMTTPGTLSSTASLVTGPIAV 873
               + TE S   T+  T +     S     TT + TS    TT  T  S  + V    + 
Sbjct: 1053 TTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSK 1112

Query: 874  QTTAGKQLSLTHPEILVPQISTEGG----ISTERNRVIVDATTGLIPLTSVPTSAKEMTT 929
             TTA                STEG     +ST  +     +TTG   +T+V T+  E TT
Sbjct: 1113 TTTA----------------STEGSEATTVSTTSSETTTASTTG-SEMTTVFTTVSETTT 1155

Query: 930  --KLGVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSATFAVQSSTQSPTTVSSSASVN 987
               +G  A  S A+ S  T+ S + +  +TA     ++ T +   S  +  + S S +  
Sbjct: 1156 VSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNT 1215

Query: 988  SC 989
            +C
Sbjct: 1216 AC 1217



 Score =  118 bits (296), Expect = 3e-26
 Identities = 200/902 (22%), Positives = 348/902 (38%), Gaps = 74/902 (8%)

Query: 134  STVSSKEGVMVQTSG-KSHAASDAPENLTLLAETADARGRSGSSSRTNFTILPVGYSLEI 192
            ST+ S E  M  T G ++   S A   +T +        R+ +      T+   G     
Sbjct: 297  STMGS-ETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTT 355

Query: 193  ATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTASEMGTERAMGLSEEWTVH--S 250
            A+ + S++   ++      ++S+E  E   A    S   SE  T    G SE  TV    
Sbjct: 356  ASIMGSETSTDSTTGSETTTASTEGSETTTA----STEGSEATTVSTTG-SETTTVSITD 410

Query: 251  QEATTSAWSPSFLPAL------------EMGELT---TPSRKRNSSGPDLSWLHFYRTAA 295
             E TT+    S + A+            E  E+T   T   +  ++  + S      TA 
Sbjct: 411  SETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAG 470

Query: 296  SSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVSK 355
            S      ++ SE+T   N  TGL++++V  T      T  T+G   T  S T S      
Sbjct: 471  SETKTAYTTGSETTTASN--TGLETTTVF-TIGSDTTTASTEGSETTAVSATGSEMTTVS 527

Query: 356  TEGFPKDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQND 415
            TEG    +   T S +  +S + +E+   S         E  E +T +  G  +     +
Sbjct: 528  TEGSENTTVSTTGSETTTVSTTGLETTTTST--------EGSEMTTVSTTGAETTTDSTE 579

Query: 416  SPTFGEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADVTGSSAS 475
                     A S      +  S+  T S + +       T     T STTS++ T +S  
Sbjct: 580  GSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTE 639

Query: 476  YPEGVNASVLTQFSDSTVQSGGSHTALGDRSYSESSSTSSSESLNSSAPRGER----SIA 531
              E    S  T    + V + GS   +     SE+++ S++ S  + +  G      SI 
Sbjct: 640  GSETTTVST-TDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSIT 698

Query: 532  GISYGQVRGTAIEQRTSSDHTDHTYLSS--------TFTKGERALLSITDNS--SSSDIV 581
            G    +V  T  E  T+S        +S          T+G     + T+ S  +S+   
Sbjct: 699  GSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTT 758

Query: 582  ESSTSYIKISNSSHSEYSSFFHAQTERSNISSYDGEYAQPSTESPVLHTSNLPSYTPTIN 641
             S T+    ++S  +  S      T  S I S   + +  S++   + T N  +   +  
Sbjct: 759  GSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTT 818

Query: 642  MPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSILPS-TRASVH 700
               T+ V    +E +  S++ S +++++S+ G      S   S    +S   S T  +  
Sbjct: 819  ASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATT 878

Query: 701  LLKSTSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQ--SSSTPVLPRARETPVTSF 758
            +   T+ AST  S + +       T+T++      TT+    S +T       ET   S 
Sbjct: 879  IGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAST 938

Query: 759  QTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPS 818
            + S +T+  T    S+T  + ++ +         S++ +  +  +E+T   T  S    +
Sbjct: 939  EGSELTTVSTT--GSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTA 996

Query: 819  LTESSTEQTLPATSTNLAQMSPTFTTTILKTSQPLMTTPGTLSSTASLVTGPIAVQTTAG 878
              E S   T+ +T +    +S T T T + +++   TT  T+++  S  T   AV TT  
Sbjct: 997  SIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETT--TVTTAGSETT---AVYTTGS 1051

Query: 879  KQLSLTHPEILVPQISTEGGISTERNRVIVDATTGLIP---LTSVPTSAKEMTTKLGVTA 935
            +  + +        +ST G  +T  +   ++ TT        T+  T+  E TT     +
Sbjct: 1052 ETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGS 1111

Query: 936  EYSPASRSLGTSPSPQTTVVSTAEDLAPKSAT-------FAVQSSTQSPTTVSSSASVNS 988
            + + AS    T  S  TTV +T+ +    S T       F   S T + +T+ S A+ +S
Sbjct: 1112 KTTTAS----TEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSS 1167

Query: 989  CA 990
             A
Sbjct: 1168 AA 1169



 Score =  110 bits (274), Expect = 1e-23
 Identities = 205/949 (21%), Positives = 368/949 (38%), Gaps = 111/949 (11%)

Query: 124  ITFYQNQEDFSTVSSKEGVMVQTSGKSHAASDAPENLTLLAETADARGRSGSSSRTNFTI 183
            IT     +  +T +S EG   +T+  + A S+     T  +ET  A   +G  + T FTI
Sbjct: 443  ITIASTSDSETTTASTEGS--ETTTVTTAGSETKTAYTTGSETTTA-SNTGLETTTVFTI 499

Query: 184  LPVGYSLEIATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTASEMGTERAMGLS 243
               G     A+   S++  +++    + + S+E  E      T S T SE  T    GL 
Sbjct: 500  ---GSDTTTASTEGSETTAVSATGSEMTTVSTEGSENT----TVSTTGSETTTVSTTGLE 552

Query: 244  EEWTVH--SQEATTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASSPLLD 301
               T    S+  T S            G  TT +    S    +S      T AS+   +
Sbjct: 553  TTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSE 612

Query: 302  LSSSSES-TEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVSKTEGFP 360
             +S+S + +E    ST    ++ + T+     TV T     T+ S T S   ++ TEG  
Sbjct: 613  TTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSE 672

Query: 361  ----------------------------KDSRIATTSSSVLLSPSAVESRRNSRVTGNPG 392
                                        + ++++TT S    + +       + +TG+  
Sbjct: 673  TTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSET 732

Query: 393  DEEFIEPSTENEFGLTSLRWQNDSPTFGEHQLAS--SSEVQNGSPMSQTETVSRSVAPMR 450
                 E S             + S T  E   AS  SSE    S M    T++ ++    
Sbjct: 733  TTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSET 792

Query: 451  GGEITAHWLLTN-----------STTSADVTGSSASYPEGVNASVLTQFSDSTVQSGGSH 499
                TA   +T            STT+++ T  S +  E + AS     + +T  + GS 
Sbjct: 793  TKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSE 852

Query: 500  TALGDRSYSESS--STSSSESLNSSAPRGERSIAGISYGQVRGTAIE-QRTSSDHTDHTY 556
            T       SE++  ST SSE+  ++    E + A     +   T+ E   T++  T+ + 
Sbjct: 853  TTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSE 912

Query: 557  LSSTFTKGERALLSITDNSSSSDIVESSTSYIKISNSSHSEYSSFFHAQTERSNISSYDG 616
            +++  T G     + T+ S ++      +    +S +  SE  +     +E + +++   
Sbjct: 913  ITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTG-SETITVSAEGSETTTVTTMGS 971

Query: 617  EYAQPST---ESPVLHTSNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSG 673
            E    ST   E+  + T+   + T +I    T+ V  T +E  + S++ + ++ +S+   
Sbjct: 972  ETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGS 1031

Query: 674  PPLPLPSV-SQSHHLFSS----ILPSTRASVHLLKSTSDASTPWSSSPSPLPVSLTTS-- 726
                + +  S++  ++++       ST  S     ST+ + T  +S+      +++TS  
Sbjct: 1032 ETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGS 1091

Query: 727  --TSAPLSVSQTTLPQ-------------SSSTPVLPRARETPVTSFQTSTMTSFMTMLH 771
              T+A  + S+TT                S +T V   + ET   S   S MT+  T + 
Sbjct: 1092 GTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVS 1151

Query: 772  SSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESSTEQTLPAT 831
             + T      ST   E   + +      +  TE ++  TT S      T +ST  +   T
Sbjct: 1152 ETTTV-----STIGSEATTSSAAGSEATTTSTEGSE-TTTASTAGSETTTASTAGSETTT 1205

Query: 832  STNLAQMSPTFTTTILKTSQPLMTTPGTLSSTASLVTGPIAVQTTAGKQ---LSLTHPEI 888
            ++     + T  TT  +TS P  ++ G+ ++TA ++     + +TA  +    SLT  E 
Sbjct: 1206 ASTSGSETNTACTTGSETSTP--SSAGSETNTAFIIGSETTIASTASLEPTATSLTGSET 1263

Query: 889  LVPQISTEGGIS-----TERNRVIVDAT-TGLIPLTSVPTSAKEMT-TKLGVTAEYSPAS 941
                I+  G  +     +    V+  AT   + P+T+ P S    T T+L        AS
Sbjct: 1264 TTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRL-------TAS 1316

Query: 942  RSLGTSPSPQTTVVSTAEDLAPKSA--TFAVQSSTQSPTTVSSSASVNS 988
             S+  +P    T  S A    P     T  + +ST   ++ +S+  V +
Sbjct: 1317 SSVTMAPGMDFT-ASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRT 1364



 Score =  105 bits (261), Expect = 4e-22
 Identities = 191/857 (22%), Positives = 342/857 (39%), Gaps = 147/857 (17%)

Query: 230 TASEMGTERAMGLSEEWTVHSQEATTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLH 289
           TAS  G+E    L     + + E TT++ + S        E TTPS       P  S   
Sbjct: 17  TASTTGSETTTIL-----IKASETTTASTAGS--------ETTTPS-------PTGSQTT 56

Query: 290 FYRTAASSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVS 349
               + S      ++ SE+T   +  +G  ++S++ ++T    TV T G   T  S+T +
Sbjct: 57  IVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSET----TVSTAGSETTTVSITGT 112

Query: 350 LGPVSKTEGFPKDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTS 409
              +    G    +   T+S + + S +  E+   S V    G E     + ++E    S
Sbjct: 113 ETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTV----GSETTTAYTADSETTAAS 168

Query: 410 LRWQNDSPTFGEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADV 469
                 +  F     A S  +   +  S+T TVS +     G E T     T STT ++ 
Sbjct: 169 TTGSEMTTVF----TAGSETITPSTAGSETTTVSTA-----GSETT-----TVSTTGSET 214

Query: 470 TGSSASYPEGVNAS--------VLTQFSDSTVQSGGS------------HTALGDRSYSE 509
           T +S ++ E   AS        V T  S++TV + GS            +TA  + S + 
Sbjct: 215 TTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTT 274

Query: 510 SSSTSSSESLNSSAPRGERSIAGISYGQ-VRGTAIEQRTSSDHTDHTYLSSTFTKGERAL 568
           ++ST+  E+  +S    E ++A     +    + I   T+   T  + +++ F  G   +
Sbjct: 275 TASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETI 334

Query: 569 LSITDNSSSSDIVESSTSYIKISNSSHSEYSSFFHAQTERSNISSYDGEYAQPSTE-SPV 627
            + T  S ++  V ++ S    ++   SE S+     +E +  S+   E    STE S  
Sbjct: 335 RASTVGSETT-TVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEA 393

Query: 628 LHTSNLPSYTPTINMPNT---------------------SVVLDTDAEFVSDSSSSSSSS 666
              S   S T T+++ ++                     +    T+   ++ +S+S S +
Sbjct: 394 TTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSET 453

Query: 667 SSSSSSGPPLPLPSV--SQSHHLFSSILPSTRASVHLLKST------SDASTPWSSSPSP 718
           +++S+ G      +   S++   +++   +T AS   L++T      SD +T  +     
Sbjct: 454 TTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSET 513

Query: 719 LPVSLTTSTSAPLSV---SQTTLPQ--SSSTPVLPRARETPVTSFQTSTMTSFMT----- 768
             VS T S    +S      TT+    S +T V     ET  TS + S MT+  T     
Sbjct: 514 TAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAET 573

Query: 769 -------------MLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPL 815
                            S+T  + +  + +      +S++ S  +  +E+T A TT+S  
Sbjct: 574 TTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSET 633

Query: 816 PPSLTESSTEQTLPATSTNLAQMSPT------------FTTTILKT-SQPLMTTPGTLSS 862
             + TE S   T+  T +    +S T             TTT+  T S+  ++T G+ ++
Sbjct: 634 TTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTT 693

Query: 863 TASLVTGPIAVQTTAGKQLSLTH---PEILVPQI--------STEGG----ISTERNRVI 907
           T S+        +T G + + T     EI    I        STEG      STE +   
Sbjct: 694 TVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETT 753

Query: 908 VDATTGLIPLTSVPTSAKEMTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSAT 967
             +TTG    T+  TS++  TT   +    +  + ++G+  +  +T  S    +  +++ 
Sbjct: 754 SASTTGSETTTASTTSSE--TTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSE 811

Query: 968 FAVQSSTQSPTTVSSSA 984
             + S+T S TT  S+A
Sbjct: 812 TTIASTTASETTTVSTA 828



 Score = 93.6 bits (231), Expect = 1e-18
 Identities = 138/603 (22%), Positives = 237/603 (39%), Gaps = 69/603 (11%)

Query: 445 SVAPMRGGEITAHWLLTNSTTSADVTGSSASYPE---------GVNASVLTQFS-----D 490
           + A   G E T   +  + TT+A   GS  + P           ++ S +T  S     +
Sbjct: 16  TTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSEN 75

Query: 491 STVQSGGSHTALGDRSYSESS-STSSSESLNSSAPRGERSIAGISYGQVRGTAIEQRTSS 549
           +TV S GS T     + SE++ ST+ SE+          SI G     V     E  T+S
Sbjct: 76  TTVSSAGSGTTTASMAGSETTVSTAGSETTTV-------SITGTETTMVSAMGSETTTNS 128

Query: 550 DHTDHTYLSSTFTKGERALLSITDNSSSSDIVESSTSYIKISNSSHSEYSSFFHAQTERS 609
             +  T ++ST       + ++   ++++   +S T+    ++++ SE ++ F A +E  
Sbjct: 129 TTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETT---AASTTGSEMTTVFTAGSETI 185

Query: 610 NISSYDGEYAQPST---ESPVLHTSNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSS 666
             S+   E    ST   E+  + T+   + T +     T+      +E    S++ S ++
Sbjct: 186 TPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETT 245

Query: 667 SSSSSSGPPLPLPSVSQSHHLFSSILPSTRASVHLLKSTSDASTPWSSSPSPLPVSLTTS 726
            S++ S         S+++  F+    +T AS    ++T+ AST  S       +   T+
Sbjct: 246 VSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTA-ASTTGSEPTMASTMGSETT 304

Query: 727 TSAPLSVSQTTLPQSSS--TPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADL-----K 779
            ++ +    T +  +SS  T V     ET   S   S  T+  T    + TA +      
Sbjct: 305 MASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETS 364

Query: 780 SQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESSTEQTLPATSTNLAQMS 839
           + ST   E     ++     +  TE ++A T ++    + T S T+     T T  ++M+
Sbjct: 365 TDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMT 424

Query: 840 PTFTT--------------TILKTSQPLMTTPGTLSSTASLVT----GPIAVQTTAGKQL 881
              TT              TI  TS    TT  T  S  + VT          TT  +  
Sbjct: 425 AVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETT 484

Query: 882 SLTHPEILVPQISTEGG----ISTERNRVIVDATTGLIPLTSVPTSAKEMTTKLGVTAEY 937
           + ++  +    + T G      STE +     + TG   +T+V T   E TT     +E 
Sbjct: 485 TASNTGLETTTVFTIGSDTTTASTEGSETTAVSATG-SEMTTVSTEGSENTTVSTTGSET 543

Query: 938 SPAS------RSLGTSPSPQTTV----VSTAEDLAPKSATFAVQSSTQSPTTVSSSASVN 987
           +  S       +  T  S  TTV      T  D    S T A  ++    TTVS++ S N
Sbjct: 544 TTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSEN 603

Query: 988 SCA 990
           + A
Sbjct: 604 TTA 606



 Score = 75.1 bits (183), Expect = 4e-13
 Identities = 146/624 (23%), Positives = 255/624 (40%), Gaps = 74/624 (11%)

Query: 116  NTEAHVENITFYQNQEDFSTVSS--KEGVMVQTSGK---SHAASDAPENLTLLAETADAR 170
            N+E  + + T      + +TVS+   E +   T+G    +  +++  E  T   E ++  
Sbjct: 809  NSETTIASTT----ASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETT 864

Query: 171  GRSGSSSRTNFTILPVGYSLEIATALTSQSGNLASESLHLPSSSSEFDE--RIAAFQTKS 228
              S  SS T  T   +G     A+   S++   ++E     ++S+E  E   ++   +++
Sbjct: 865  TASTESSETT-TATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSET 923

Query: 229  GTASEMGTERAMGLSEEW------TVHSQEATTSAWSPSFLPALEMGELTTPSRKRNSSG 282
             TAS  G+E     +E        T  S+  T SA          MG  TT +    S  
Sbjct: 924  TTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSET 983

Query: 283  PDLSWLHFYRTAASSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRT 342
              +S      TA S         SE+T    +STG ++++VS T T    T  T+G   T
Sbjct: 984  TTVS------TAGSETTTASIEGSETTTV--SSTGSETTTVSTTGTETTITS-TEGSETT 1034

Query: 343  LRSLTVSLGPVSKTEGFPKDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTE 402
                TV+      T  +   S   TTS+      + V +  +   T +  D E    ST 
Sbjct: 1035 ----TVTTAGSETTAVYTTGSETTTTSTEGS-ETTTVSTTGSETTTASTADLETTTVSTS 1089

Query: 403  NEFGLTSLRWQNDSPTF---GEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWL 459
                 T+    +++ T    G     +S+E    + +S T + + + A   G E+T  + 
Sbjct: 1090 GSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSET-TTASTTGSEMTTVFT 1148

Query: 460  LTNSTTS-----ADVTGSSASYPEGVNASVLTQFSDSTVQS-GGSHTALGDRSYSESSST 513
              + TT+     ++ T SSA+  E    S  T+ S++T  S  GS T     + SE+++ 
Sbjct: 1149 TVSETTTVSTIGSEATTSSAAGSEATTTS--TEGSETTTASTAGSETTTASTAGSETTTA 1206

Query: 514  SSSES-LNSSAPRGERSIAGISYGQVRGTAI---EQRTSSDHTDHTYLSSTFTKGERALL 569
            S+S S  N++   G  +    S G    TA     + T +        +++ T  E   +
Sbjct: 1207 STSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTV 1266

Query: 570  SIT-DNSSSSDIVESSTSYI----------KISNSSHSEYSSFFHAQTERSNIS-----S 613
            SIT   ++++    SST+++           I+N+  S   +     T  S+++      
Sbjct: 1267 SITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMD 1326

Query: 614  YDGEYAQPSTESPVLHTSNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSSSSSS--S 671
            +    A  +    VL+TS L   T T+   +T     T A  V  ++ S+   +SS+   
Sbjct: 1327 FTASAASHTVPGIVLNTSGLG--TSTMGASST-----TSAHGVRTTTGSTREPTSSTFQE 1379

Query: 672  SGP-PLPLPSVSQSHHLFSSILPS 694
            +GP  +   +VS SH   + I PS
Sbjct: 1380 TGPVSMGTNTVSMSHTPTNVIKPS 1403



 Score = 61.2 bits (147), Expect = 6e-09
 Identities = 106/542 (19%), Positives = 202/542 (37%), Gaps = 41/542 (7%)

Query: 644  NTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSILPSTRASVHLLK 703
            NT+    T +E  +     +S ++++S++G     PS + S    ++I+  + + +    
Sbjct: 14   NTTTASTTGSE-TTTILIKASETTTASTAGSETTTPSPTGSQ---TTIVSISGSEITTTS 69

Query: 704  STSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQSSSTPVLPRARETPVTSFQTSTM 763
            +    +T  SS+ S      TT++ A    + +T    ++T  +     T V++  + T 
Sbjct: 70   TAGSENTTVSSAGS----GTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETT 125

Query: 764  TSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESS 823
            T+  T   ++ T+   S++T         S++ +  +  +E+T A TT S +    T  S
Sbjct: 126  TNSTTSSETTVTSTAGSETTTVS---TVGSETTTAYTADSETTAASTTGSEMTTVFTAGS 182

Query: 824  TEQTLPATSTNLAQMSPTFTTTILKTSQPLMTTPGTLSSTASLVTGPIAVQTTAGKQLSL 883
             E   P+T+      S T T +   +    ++T G+ ++TAS         +T G + + 
Sbjct: 183  -ETITPSTAG-----SETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTK 236

Query: 884  THPEILVPQISTEGGIST-------ERNRVIV-DATTGLIPLTSVPTSAKEMTTKLGVTA 935
                     +ST G  +T       E N     D+ T     T   T+A   T      A
Sbjct: 237  VSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMA 296

Query: 936  EYSPASRSLGTSPSPQTTVVSTAED-----LAPKSATFAVQSSTQSPTTVSSSASVNSCA 990
                +  ++ ++  P+TT VSTA        A  S T    +     TTVS++ S  + A
Sbjct: 297  STMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTA 356

Query: 991  VNPCLHNGECVADNTSRGYHCRCPPSWQGDDCSVDVNE-----CLSNPCPSTAMCNNTQG 1045
                +   E   D+T+         S +G + +    E      +S     T   + T  
Sbjct: 357  ---SIMGSETSTDSTTGSE--TTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDS 411

Query: 1046 SFICKCPVGYQLEKGICNLVRTFVTEFKLKRTFLNTTVEKHSDLQEVENEITKTLNMCFS 1105
                 C  G ++      +  T     +     + +T +  +     E   T T+    S
Sbjct: 412  ETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGS 471

Query: 1106 ALPSYIRSTVHASRESNAVVISLQTTFSLASNVTLFDLADRMQKCVNSCKSSAEVCQLLG 1165
               +   +    +  SN   +   T F++ S+ T           V++  S        G
Sbjct: 472  ETKTAYTTGSETTTASN-TGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEG 530

Query: 1166 SQ 1167
            S+
Sbjct: 531  SE 532


>gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1612

 Score =  134 bits (336), Expect = 8e-31
 Identities = 217/904 (24%), Positives = 370/904 (40%), Gaps = 98/904 (10%)

Query: 134 STVSSKEGVMVQTSGKSHAASDAPENLTLLAETAD----ARGRSGSSSRTNFTILPVGYS 189
           ++ +S E  +  T+G          + T  A TAD    A   +GS   T FT      +
Sbjct: 127 NSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETIT 186

Query: 190 LEIATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTASEMGTERAMGLSEEWTVH 249
              A + T+      SE+  + ++ SE      A  +++  AS MG+E     ++  T  
Sbjct: 187 PSTAGSETTTVSTAGSETTTVSTTGSETTTASTA-HSETTAASTMGSE----TTKVSTAG 241

Query: 250 SQEATTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASS----PLLDLSSS 305
           S+   ++A S +   + E  E T  +   +S     S   F  TAAS+    P +  +  
Sbjct: 242 SETTVSTAGSETTAASTEDSE-TNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMG 300

Query: 306 SESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVSKTEGFPKDSRI 365
           SE+T  + ++ G +++ VS T +  V TVF   G  T+R+ TV  G  + T      +  
Sbjct: 301 SETT--MASTIGPETTKVS-TASSEVTTVFA-AGSETIRASTV--GSETTT---VSTTGS 351

Query: 366 ATTSSSVLLSPSAVESRRNSR-VTGNPGDEEFIEPSTENEFGLTSLRWQNDSPTFGEHQL 424
            TT++S++ S ++ +S   S   T +    E    STE     T     +++ T      
Sbjct: 352 ETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDS 411

Query: 425 ASSSEVQNGSPMSQTETV--SRSVAPMRGGEITAHWLLTNSTTSADVTGSSASYPEGVNA 482
            +++    GS M+   T     + A   G EIT      + TT+A   GS  +      +
Sbjct: 412 ETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGS 471

Query: 483 SVLTQFSDSTVQSGGSHTALGDR------SYSESSSTSSSESLNSSAPRGER---SIAGI 533
              T ++  +  +  S+T L         S + ++ST  SE+   SA   E    S  G 
Sbjct: 472 ETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGS 531

Query: 534 SYGQVRGTAIEQRTSSDHTDHTYLSSTFTKG-ERALLSITDNSSSSDIVESSTSYIKISN 592
               V  T  E  T S  T     ++T T+G E   +S T   +++D  E S +    ++
Sbjct: 532 ENTTVSTTGSETTTVS--TTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGT--TAAS 587

Query: 593 SSHSEYSSFFHAQTERSNISSYDGEYAQPST---ESPVLHTSNLPSYTPTINMPNTSVVL 649
           ++ SE ++   A +E +  S+ D E    ST   E+    T++  + T +     T+ V 
Sbjct: 588 TAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVS 647

Query: 650 DTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSILPSTRASVHLLKSTSDAS 709
            TD+E    S++ S  + +S+       + +      + +    +T  S+     T   +
Sbjct: 648 TTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSI-----TGSET 702

Query: 710 TPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQSSSTPVLPRARETPVTSFQTSTMTSFMTM 769
           T  S++ S      TT+++    ++  ++  S +T       ET   S + S  TS  T 
Sbjct: 703 TKVSTTGS----ETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTT 758

Query: 770 LHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESST----- 824
              + TA   S  T     + +E+   S +   +E+TK  T +S +    TE+S      
Sbjct: 759 GSETTTASTTSSETTMASIMGSETTMASTIG--SETTKVSTASSKMTTVFTENSETTIAS 816

Query: 825 -------------EQTLPATSTNLAQMSPTFTTTILKTSQ-PLMTTPGTLSSTASLVTGP 870
                         +T+PA++      S T TTT  + S+    +T G+ ++TAS  +  
Sbjct: 817 TTASETTTVSTAGSETIPASTAG----SETTTTTSTEGSETTTASTEGSETTTASTESSE 872

Query: 871 IAVQTTAGKQLSLTHPEILVPQISTEGG----ISTERNRVIVDATTGLIPLTSVPTSAKE 926
               TT G + +           STEG      STE +     +T G   +T+V T+  E
Sbjct: 873 TTTATTIGSETTTA---------STEGSETTTTSTEGSETTTASTEG-SEITTVSTTGSE 922

Query: 927 MTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSATFAVQSSTQSPTTVSSSASV 986
            TT     +E + AS    T  S  TTV +T  +    SA     S T + TT+ S  + 
Sbjct: 923 TTTASTEGSETTTAS----TEGSELTTVSTTGSETITVSAE---GSETTTVTTMGSETTT 975

Query: 987 NSCA 990
            S A
Sbjct: 976 ASTA 979



 Score =  129 bits (323), Expect = 3e-29
 Identities = 202/902 (22%), Positives = 348/902 (38%), Gaps = 76/902 (8%)

Query: 114  ESNTEAHVENITFYQNQEDFSTVSSKEGVMVQTSGKSHAASDAPENLTLLAETADARGRS 173
            +S T +     +   ++   ++    E   V T+G         ++ T    T  +   +
Sbjct: 366  DSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTA 425

Query: 174  GSSSRTNFTILPV-GYSLEIATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTAS 232
             S++    T     G  + IA+   S++   ++E     + ++   E   A+ T S T +
Sbjct: 426  VSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTT 485

Query: 233  EMGTERAMGLSEEWTVHSQEATTSAWSPSFLPALEMG-ELTTPSRKRNSSGPDLSWLHFY 291
               T   +  +  +T+ S   T S            G E+TT S + + +    +     
Sbjct: 486  ASNT--GLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSET 543

Query: 292  RTAASSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLG 351
             T +++ L   ++S+E +E    ST    ++   T+        T G   T    TVS  
Sbjct: 544  TTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETT----TVSTA 599

Query: 352  PVSKTEGFPKDSRIATTSSSVLLSPSAVESRRNSRVT--GNPGDEEFIEPSTENEFGLTS 409
                T     DS   TTS+S   S +   S  +S  T     G E     +T++E  + S
Sbjct: 600  DSENTTASTADSE--TTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVS 657

Query: 410  LRWQNDSPTFGEHQLASSSEVQNGSPMSQT---ETVSRSVAPMRGGEITAHWLLTNSTTS 466
                    T G  +  +S+E    + +S T    TVS   +      IT       STT 
Sbjct: 658  --------TTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTG 709

Query: 467  ADVTGSSASYPEGVNASVLTQFSDSTVQSGGSHTALGDRSYSE--SSSTSSSESLNSSAP 524
            ++ T +S    E   AS+ T    +T  + GS T       SE  S+ST+ SE+  +S  
Sbjct: 710  SETTTTSTEGSEITTASI-TGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTT 768

Query: 525  RGERSIAGISYGQVR-GTAIEQRTSSDHTDHTYLSSTFTKGERALLSITDNSSSSDIVES 583
              E ++A I   +    + I   T+   T  + +++ FT+     ++ T  S ++ +  +
Sbjct: 769  SSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTA 828

Query: 584  STSYIKISNSSHSEYSSFFHAQTERSNISSYDGEYAQPSTESPVLHTSNLPSYTPTINMP 643
             +  I  S +     ++     +E +  S+   E    STES    T+       TI   
Sbjct: 829  GSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTAT------TIGSE 882

Query: 644  NTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSI------LPSTRA 697
             T+    T+    + +S+  S ++++S+ G  +   S + S    +S         ST  
Sbjct: 883  TTTA--STEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEG 940

Query: 698  SVHLLKSTSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQSSSTPVLPRARETPVTS 757
            S     ST+ + T   S+      ++TT  S   + S      S +T V     ET   S
Sbjct: 941  SELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAG---SETTTVSTAGSETTTAS 997

Query: 758  FQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPT---ESTKAVTTNSP 814
             + S  T+      SS  ++  + ST   E  IT ++     ++ T   E+T   TT S 
Sbjct: 998  IEGSETTTV-----SSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSE 1052

Query: 815  LPPSLTESSTEQTLPATSTNLAQMSPT-FTTTILKTSQPLMTTPGTLSSTASLVTGPIAV 873
               + TE S   T+  T +     S     TT + TS    TT  T  S  + V    + 
Sbjct: 1053 TTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSK 1112

Query: 874  QTTAGKQLSLTHPEILVPQISTEGG----ISTERNRVIVDATTGLIPLTSVPTSAKEMTT 929
             TTA                STEG     +ST  +     +TTG   +T+V T+  E TT
Sbjct: 1113 TTTA----------------STEGSEATTVSTTSSETTTASTTG-SEMTTVFTTVSETTT 1155

Query: 930  --KLGVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSATFAVQSSTQSPTTVSSSASVN 987
               +G  A  S A+ S  T+ S + +  +TA     ++ T +   S  +  + S S +  
Sbjct: 1156 VSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNT 1215

Query: 988  SC 989
            +C
Sbjct: 1216 AC 1217



 Score =  118 bits (296), Expect = 3e-26
 Identities = 200/902 (22%), Positives = 348/902 (38%), Gaps = 74/902 (8%)

Query: 134  STVSSKEGVMVQTSG-KSHAASDAPENLTLLAETADARGRSGSSSRTNFTILPVGYSLEI 192
            ST+ S E  M  T G ++   S A   +T +        R+ +      T+   G     
Sbjct: 297  STMGS-ETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTT 355

Query: 193  ATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTASEMGTERAMGLSEEWTVH--S 250
            A+ + S++   ++      ++S+E  E   A    S   SE  T    G SE  TV    
Sbjct: 356  ASIMGSETSTDSTTGSETTTASTEGSETTTA----STEGSEATTVSTTG-SETTTVSITD 410

Query: 251  QEATTSAWSPSFLPAL------------EMGELT---TPSRKRNSSGPDLSWLHFYRTAA 295
             E TT+    S + A+            E  E+T   T   +  ++  + S      TA 
Sbjct: 411  SETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAG 470

Query: 296  SSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVSK 355
            S      ++ SE+T   N  TGL++++V  T      T  T+G   T  S T S      
Sbjct: 471  SETKTAYTTGSETTTASN--TGLETTTVF-TIGSDTTTASTEGSETTAVSATGSEMTTVS 527

Query: 356  TEGFPKDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQND 415
            TEG    +   T S +  +S + +E+   S         E  E +T +  G  +     +
Sbjct: 528  TEGSENTTVSTTGSETTTVSTTGLETTTTST--------EGSEMTTVSTTGAETTTDSTE 579

Query: 416  SPTFGEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADVTGSSAS 475
                     A S      +  S+  T S + +       T     T STTS++ T +S  
Sbjct: 580  GSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTE 639

Query: 476  YPEGVNASVLTQFSDSTVQSGGSHTALGDRSYSESSSTSSSESLNSSAPRGER----SIA 531
              E    S  T    + V + GS   +     SE+++ S++ S  + +  G      SI 
Sbjct: 640  GSETTTVST-TDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSIT 698

Query: 532  GISYGQVRGTAIEQRTSSDHTDHTYLSS--------TFTKGERALLSITDNS--SSSDIV 581
            G    +V  T  E  T+S        +S          T+G     + T+ S  +S+   
Sbjct: 699  GSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTT 758

Query: 582  ESSTSYIKISNSSHSEYSSFFHAQTERSNISSYDGEYAQPSTESPVLHTSNLPSYTPTIN 641
             S T+    ++S  +  S      T  S I S   + +  S++   + T N  +   +  
Sbjct: 759  GSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTT 818

Query: 642  MPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSILPS-TRASVH 700
               T+ V    +E +  S++ S +++++S+ G      S   S    +S   S T  +  
Sbjct: 819  ASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATT 878

Query: 701  LLKSTSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQ--SSSTPVLPRARETPVTSF 758
            +   T+ AST  S + +       T+T++      TT+    S +T       ET   S 
Sbjct: 879  IGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAST 938

Query: 759  QTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPS 818
            + S +T+  T    S+T  + ++ +         S++ +  +  +E+T   T  S    +
Sbjct: 939  EGSELTTVSTT--GSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTA 996

Query: 819  LTESSTEQTLPATSTNLAQMSPTFTTTILKTSQPLMTTPGTLSSTASLVTGPIAVQTTAG 878
              E S   T+ +T +    +S T T T + +++   TT  T+++  S  T   AV TT  
Sbjct: 997  SIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETT--TVTTAGSETT---AVYTTGS 1051

Query: 879  KQLSLTHPEILVPQISTEGGISTERNRVIVDATTGLIP---LTSVPTSAKEMTTKLGVTA 935
            +  + +        +ST G  +T  +   ++ TT        T+  T+  E TT     +
Sbjct: 1052 ETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGS 1111

Query: 936  EYSPASRSLGTSPSPQTTVVSTAEDLAPKSAT-------FAVQSSTQSPTTVSSSASVNS 988
            + + AS    T  S  TTV +T+ +    S T       F   S T + +T+ S A+ +S
Sbjct: 1112 KTTTAS----TEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSS 1167

Query: 989  CA 990
             A
Sbjct: 1168 AA 1169



 Score =  109 bits (273), Expect = 2e-23
 Identities = 205/949 (21%), Positives = 368/949 (38%), Gaps = 111/949 (11%)

Query: 124  ITFYQNQEDFSTVSSKEGVMVQTSGKSHAASDAPENLTLLAETADARGRSGSSSRTNFTI 183
            IT     +  +T +S EG   +T+  + A S+     T  +ET  A   +G  + T FTI
Sbjct: 443  ITIASTSDSETTTASTEGS--ETTTVTTAGSETKTAYTTGSETTTA-SNTGLETTTVFTI 499

Query: 184  LPVGYSLEIATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTASEMGTERAMGLS 243
               G     A+   S++  +++    + + S+E  E      T S T SE  T    GL 
Sbjct: 500  ---GSDTTTASTEGSETTAVSATGSEMTTVSTEGSENT----TVSTTGSETTTVSTTGLE 552

Query: 244  EEWTVH--SQEATTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASSPLLD 301
               T    S+  T S            G  TT +    S    +S      T AS+   +
Sbjct: 553  TTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSE 612

Query: 302  LSSSSES-TEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVSKTEGFP 360
             +S+S + +E    ST    ++ + T+     TV T     T+ S T S   ++ TEG  
Sbjct: 613  TTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSE 672

Query: 361  ----------------------------KDSRIATTSSSVLLSPSAVESRRNSRVTGNPG 392
                                        + ++++TT S    + +       + +TG+  
Sbjct: 673  TTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSET 732

Query: 393  DEEFIEPSTENEFGLTSLRWQNDSPTFGEHQLAS--SSEVQNGSPMSQTETVSRSVAPMR 450
                 E S             + S T  E   AS  SSE    S M    T++ ++    
Sbjct: 733  TTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSET 792

Query: 451  GGEITAHWLLTN-----------STTSADVTGSSASYPEGVNASVLTQFSDSTVQSGGSH 499
                TA   +T            STT+++ T  S +  E + AS     + +T  + GS 
Sbjct: 793  TKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSE 852

Query: 500  TALGDRSYSESS--STSSSESLNSSAPRGERSIAGISYGQVRGTAIE-QRTSSDHTDHTY 556
            T       SE++  ST SSE+  ++    E + A     +   T+ E   T++  T+ + 
Sbjct: 853  TTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSE 912

Query: 557  LSSTFTKGERALLSITDNSSSSDIVESSTSYIKISNSSHSEYSSFFHAQTERSNISSYDG 616
            +++  T G     + T+ S ++      +    +S +  SE  +     +E + +++   
Sbjct: 913  ITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTG-SETITVSAEGSETTTVTTMGS 971

Query: 617  EYAQPST---ESPVLHTSNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSG 673
            E    ST   E+  + T+   + T +I    T+ V  T +E  + S++ + ++ +S+   
Sbjct: 972  ETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGS 1031

Query: 674  PPLPLPSV-SQSHHLFSS----ILPSTRASVHLLKSTSDASTPWSSSPSPLPVSLTTS-- 726
                + +  S++  ++++       ST  S     ST+ + T  +S+      +++TS  
Sbjct: 1032 ETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGS 1091

Query: 727  --TSAPLSVSQTTLPQ-------------SSSTPVLPRARETPVTSFQTSTMTSFMTMLH 771
              T+A  + S+TT                S +T V   + ET   S   S MT+  T + 
Sbjct: 1092 GTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVS 1151

Query: 772  SSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESSTEQTLPAT 831
             + T      ST   E   + +      +  TE ++  TT S      T +ST  +   T
Sbjct: 1152 ETTTV-----STIGSEATTSSAAGSEATTTSTEGSE-TTTASTAGSETTTASTAGSETTT 1205

Query: 832  STNLAQMSPTFTTTILKTSQPLMTTPGTLSSTASLVTGPIAVQTTAGKQ---LSLTHPEI 888
            ++     + T  TT  +TS P  ++ G+ ++TA ++     + +TA  +    SLT  E 
Sbjct: 1206 ASTSGSETNTACTTGSETSTP--SSAGSETNTAFIIGSESTIASTASLEPTATSLTGSET 1263

Query: 889  LVPQISTEGGIS-----TERNRVIVDAT-TGLIPLTSVPTSAKEMT-TKLGVTAEYSPAS 941
                I+  G  +     +    V+  AT   + P+T+ P S    T T+L        AS
Sbjct: 1264 TTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRL-------TAS 1316

Query: 942  RSLGTSPSPQTTVVSTAEDLAPKSA--TFAVQSSTQSPTTVSSSASVNS 988
             S+  +P    T  S A    P     T  + +ST   ++ +S+  V +
Sbjct: 1317 SSVTMAPGMDFT-ASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRT 1364



 Score =  105 bits (261), Expect = 4e-22
 Identities = 191/857 (22%), Positives = 342/857 (39%), Gaps = 147/857 (17%)

Query: 230 TASEMGTERAMGLSEEWTVHSQEATTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLH 289
           TAS  G+E    L     + + E TT++ + S        E TTPS       P  S   
Sbjct: 17  TASTTGSETTTIL-----IKASETTTASTAGS--------ETTTPS-------PTGSQTT 56

Query: 290 FYRTAASSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVS 349
               + S      ++ SE+T   +  +G  ++S++ ++T    TV T G   T  S+T +
Sbjct: 57  IVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSET----TVSTAGSETTTVSITGT 112

Query: 350 LGPVSKTEGFPKDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTS 409
              +    G    +   T+S + + S +  E+   S V    G E     + ++E    S
Sbjct: 113 ETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTV----GSETTTAYTADSETTAAS 168

Query: 410 LRWQNDSPTFGEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADV 469
                 +  F     A S  +   +  S+T TVS +     G E T     T STT ++ 
Sbjct: 169 TTGSEMTTVF----TAGSETITPSTAGSETTTVSTA-----GSETT-----TVSTTGSET 214

Query: 470 TGSSASYPEGVNAS--------VLTQFSDSTVQSGGS------------HTALGDRSYSE 509
           T +S ++ E   AS        V T  S++TV + GS            +TA  + S + 
Sbjct: 215 TTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTT 274

Query: 510 SSSTSSSESLNSSAPRGERSIAGISYGQ-VRGTAIEQRTSSDHTDHTYLSSTFTKGERAL 568
           ++ST+  E+  +S    E ++A     +    + I   T+   T  + +++ F  G   +
Sbjct: 275 TASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETI 334

Query: 569 LSITDNSSSSDIVESSTSYIKISNSSHSEYSSFFHAQTERSNISSYDGEYAQPSTE-SPV 627
            + T  S ++  V ++ S    ++   SE S+     +E +  S+   E    STE S  
Sbjct: 335 RASTVGSETT-TVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEA 393

Query: 628 LHTSNLPSYTPTINMPNT---------------------SVVLDTDAEFVSDSSSSSSSS 666
              S   S T T+++ ++                     +    T+   ++ +S+S S +
Sbjct: 394 TTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSET 453

Query: 667 SSSSSSGPPLPLPSV--SQSHHLFSSILPSTRASVHLLKST------SDASTPWSSSPSP 718
           +++S+ G      +   S++   +++   +T AS   L++T      SD +T  +     
Sbjct: 454 TTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSET 513

Query: 719 LPVSLTTSTSAPLSV---SQTTLPQ--SSSTPVLPRARETPVTSFQTSTMTSFMT----- 768
             VS T S    +S      TT+    S +T V     ET  TS + S MT+  T     
Sbjct: 514 TAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAET 573

Query: 769 -------------MLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPL 815
                            S+T  + +  + +      +S++ S  +  +E+T A TT+S  
Sbjct: 574 TTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSET 633

Query: 816 PPSLTESSTEQTLPATSTNLAQMSPT------------FTTTILKT-SQPLMTTPGTLSS 862
             + TE S   T+  T +    +S T             TTT+  T S+  ++T G+ ++
Sbjct: 634 TTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTT 693

Query: 863 TASLVTGPIAVQTTAGKQLSLTH---PEILVPQI--------STEGG----ISTERNRVI 907
           T S+        +T G + + T     EI    I        STEG      STE +   
Sbjct: 694 TVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETT 753

Query: 908 VDATTGLIPLTSVPTSAKEMTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSAT 967
             +TTG    T+  TS++  TT   +    +  + ++G+  +  +T  S    +  +++ 
Sbjct: 754 SASTTGSETTTASTTSSE--TTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSE 811

Query: 968 FAVQSSTQSPTTVSSSA 984
             + S+T S TT  S+A
Sbjct: 812 TTIASTTASETTTVSTA 828



 Score = 93.6 bits (231), Expect = 1e-18
 Identities = 138/603 (22%), Positives = 237/603 (39%), Gaps = 69/603 (11%)

Query: 445 SVAPMRGGEITAHWLLTNSTTSADVTGSSASYPE---------GVNASVLTQFS-----D 490
           + A   G E T   +  + TT+A   GS  + P           ++ S +T  S     +
Sbjct: 16  TTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSEN 75

Query: 491 STVQSGGSHTALGDRSYSESS-STSSSESLNSSAPRGERSIAGISYGQVRGTAIEQRTSS 549
           +TV S GS T     + SE++ ST+ SE+          SI G     V     E  T+S
Sbjct: 76  TTVSSAGSGTTTASMAGSETTVSTAGSETTTV-------SITGTETTMVSAMGSETTTNS 128

Query: 550 DHTDHTYLSSTFTKGERALLSITDNSSSSDIVESSTSYIKISNSSHSEYSSFFHAQTERS 609
             +  T ++ST       + ++   ++++   +S T+    ++++ SE ++ F A +E  
Sbjct: 129 TTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETT---AASTTGSEMTTVFTAGSETI 185

Query: 610 NISSYDGEYAQPST---ESPVLHTSNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSS 666
             S+   E    ST   E+  + T+   + T +     T+      +E    S++ S ++
Sbjct: 186 TPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETT 245

Query: 667 SSSSSSGPPLPLPSVSQSHHLFSSILPSTRASVHLLKSTSDASTPWSSSPSPLPVSLTTS 726
            S++ S         S+++  F+    +T AS    ++T+ AST  S       +   T+
Sbjct: 246 VSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTA-ASTTGSEPTMASTMGSETT 304

Query: 727 TSAPLSVSQTTLPQSSS--TPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADL-----K 779
            ++ +    T +  +SS  T V     ET   S   S  T+  T    + TA +      
Sbjct: 305 MASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETS 364

Query: 780 SQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESSTEQTLPATSTNLAQMS 839
           + ST   E     ++     +  TE ++A T ++    + T S T+     T T  ++M+
Sbjct: 365 TDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMT 424

Query: 840 PTFTT--------------TILKTSQPLMTTPGTLSSTASLVT----GPIAVQTTAGKQL 881
              TT              TI  TS    TT  T  S  + VT          TT  +  
Sbjct: 425 AVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETT 484

Query: 882 SLTHPEILVPQISTEGG----ISTERNRVIVDATTGLIPLTSVPTSAKEMTTKLGVTAEY 937
           + ++  +    + T G      STE +     + TG   +T+V T   E TT     +E 
Sbjct: 485 TASNTGLETTTVFTIGSDTTTASTEGSETTAVSATG-SEMTTVSTEGSENTTVSTTGSET 543

Query: 938 SPAS------RSLGTSPSPQTTV----VSTAEDLAPKSATFAVQSSTQSPTTVSSSASVN 987
           +  S       +  T  S  TTV      T  D    S T A  ++    TTVS++ S N
Sbjct: 544 TTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSEN 603

Query: 988 SCA 990
           + A
Sbjct: 604 TTA 606



 Score = 75.1 bits (183), Expect = 4e-13
 Identities = 146/624 (23%), Positives = 255/624 (40%), Gaps = 74/624 (11%)

Query: 116  NTEAHVENITFYQNQEDFSTVSS--KEGVMVQTSGK---SHAASDAPENLTLLAETADAR 170
            N+E  + + T      + +TVS+   E +   T+G    +  +++  E  T   E ++  
Sbjct: 809  NSETTIASTT----ASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETT 864

Query: 171  GRSGSSSRTNFTILPVGYSLEIATALTSQSGNLASESLHLPSSSSEFDE--RIAAFQTKS 228
              S  SS T  T   +G     A+   S++   ++E     ++S+E  E   ++   +++
Sbjct: 865  TASTESSETT-TATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSET 923

Query: 229  GTASEMGTERAMGLSEEW------TVHSQEATTSAWSPSFLPALEMGELTTPSRKRNSSG 282
             TAS  G+E     +E        T  S+  T SA          MG  TT +    S  
Sbjct: 924  TTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSET 983

Query: 283  PDLSWLHFYRTAASSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRT 342
              +S      TA S         SE+T    +STG ++++VS T T    T  T+G   T
Sbjct: 984  TTVS------TAGSETTTASIEGSETTTV--SSTGSETTTVSTTGTETTITS-TEGSETT 1034

Query: 343  LRSLTVSLGPVSKTEGFPKDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTE 402
                TV+      T  +   S   TTS+      + V +  +   T +  D E    ST 
Sbjct: 1035 ----TVTTAGSETTAVYTTGSETTTTSTEGS-ETTTVSTTGSETTTASTADLETTTVSTS 1089

Query: 403  NEFGLTSLRWQNDSPTF---GEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWL 459
                 T+    +++ T    G     +S+E    + +S T + + + A   G E+T  + 
Sbjct: 1090 GSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSET-TTASTTGSEMTTVFT 1148

Query: 460  LTNSTTS-----ADVTGSSASYPEGVNASVLTQFSDSTVQS-GGSHTALGDRSYSESSST 513
              + TT+     ++ T SSA+  E    S  T+ S++T  S  GS T     + SE+++ 
Sbjct: 1149 TVSETTTVSTIGSEATTSSAAGSEATTTS--TEGSETTTASTAGSETTTASTAGSETTTA 1206

Query: 514  SSSES-LNSSAPRGERSIAGISYGQVRGTAI---EQRTSSDHTDHTYLSSTFTKGERALL 569
            S+S S  N++   G  +    S G    TA     + T +        +++ T  E   +
Sbjct: 1207 STSGSETNTACTTGSETSTPSSAGSETNTAFIIGSESTIASTASLEPTATSLTGSETTTV 1266

Query: 570  SIT-DNSSSSDIVESSTSYI----------KISNSSHSEYSSFFHAQTERSNIS-----S 613
            SIT   ++++    SST+++           I+N+  S   +     T  S+++      
Sbjct: 1267 SITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMD 1326

Query: 614  YDGEYAQPSTESPVLHTSNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSSSSSS--S 671
            +    A  +    VL+TS L   T T+   +T     T A  V  ++ S+   +SS+   
Sbjct: 1327 FTASAASHTVPGIVLNTSGLG--TSTMGASST-----TSAHGVRTTTGSTREPTSSTFQE 1379

Query: 672  SGP-PLPLPSVSQSHHLFSSILPS 694
            +GP  +   +VS SH   + I PS
Sbjct: 1380 TGPVSMGTNTVSMSHTPTNVIKPS 1403



 Score = 61.2 bits (147), Expect = 6e-09
 Identities = 106/542 (19%), Positives = 202/542 (37%), Gaps = 41/542 (7%)

Query: 644  NTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSILPSTRASVHLLK 703
            NT+    T +E  +     +S ++++S++G     PS + S    ++I+  + + +    
Sbjct: 14   NTTTASTTGSE-TTTILIKASETTTASTAGSETTTPSPTGSQ---TTIVSISGSEITTTS 69

Query: 704  STSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQSSSTPVLPRARETPVTSFQTSTM 763
            +    +T  SS+ S      TT++ A    + +T    ++T  +     T V++  + T 
Sbjct: 70   TAGSENTTVSSAGS----GTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETT 125

Query: 764  TSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESS 823
            T+  T   ++ T+   S++T         S++ +  +  +E+T A TT S +    T  S
Sbjct: 126  TNSTTSSETTVTSTAGSETTTVS---TVGSETTTAYTADSETTAASTTGSEMTTVFTAGS 182

Query: 824  TEQTLPATSTNLAQMSPTFTTTILKTSQPLMTTPGTLSSTASLVTGPIAVQTTAGKQLSL 883
             E   P+T+      S T T +   +    ++T G+ ++TAS         +T G + + 
Sbjct: 183  -ETITPSTAG-----SETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTK 236

Query: 884  THPEILVPQISTEGGIST-------ERNRVIV-DATTGLIPLTSVPTSAKEMTTKLGVTA 935
                     +ST G  +T       E N     D+ T     T   T+A   T      A
Sbjct: 237  VSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMA 296

Query: 936  EYSPASRSLGTSPSPQTTVVSTAED-----LAPKSATFAVQSSTQSPTTVSSSASVNSCA 990
                +  ++ ++  P+TT VSTA        A  S T    +     TTVS++ S  + A
Sbjct: 297  STMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTA 356

Query: 991  VNPCLHNGECVADNTSRGYHCRCPPSWQGDDCSVDVNE-----CLSNPCPSTAMCNNTQG 1045
                +   E   D+T+         S +G + +    E      +S     T   + T  
Sbjct: 357  ---SIMGSETSTDSTTGSE--TTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDS 411

Query: 1046 SFICKCPVGYQLEKGICNLVRTFVTEFKLKRTFLNTTVEKHSDLQEVENEITKTLNMCFS 1105
                 C  G ++      +  T     +     + +T +  +     E   T T+    S
Sbjct: 412  ETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGS 471

Query: 1106 ALPSYIRSTVHASRESNAVVISLQTTFSLASNVTLFDLADRMQKCVNSCKSSAEVCQLLG 1165
               +   +    +  SN   +   T F++ S+ T           V++  S        G
Sbjct: 472  ETKTAYTTGSETTTASN-TGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEG 530

Query: 1166 SQ 1167
            S+
Sbjct: 531  SE 532


>gi|239740898 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1542

 Score =  134 bits (336), Expect = 8e-31
 Identities = 217/904 (24%), Positives = 370/904 (40%), Gaps = 98/904 (10%)

Query: 134  STVSSKEGVMVQTSGKSHAASDAPENLTLLAETAD----ARGRSGSSSRTNFTILPVGYS 189
            ++ +S E  +  T+G          + T  A TAD    A   +GS   T FT      +
Sbjct: 148  NSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETIT 207

Query: 190  LEIATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTASEMGTERAMGLSEEWTVH 249
               A + T+      SE+  + ++ SE      A  +++  AS MG+E     ++  T  
Sbjct: 208  PSTAGSETTTVSTAGSETTTVSTTGSETTTASTA-HSETTAASTMGSE----TTKVSTAG 262

Query: 250  SQEATTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASS----PLLDLSSS 305
            S+   ++A S +   + E  E T  +   +S     S   F  TAAS+    P +  +  
Sbjct: 263  SETTVSTAGSETTAASTEDSE-TNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMG 321

Query: 306  SESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVSKTEGFPKDSRI 365
            SE+T  + ++ G +++ VS T +  V TVF   G  T+R+ TV  G  + T      +  
Sbjct: 322  SETT--MASTIGPETTKVS-TASSEVTTVFA-AGSETIRASTV--GSETTT---VSTTGS 372

Query: 366  ATTSSSVLLSPSAVESRRNSR-VTGNPGDEEFIEPSTENEFGLTSLRWQNDSPTFGEHQL 424
             TT++S++ S ++ +S   S   T +    E    STE     T     +++ T      
Sbjct: 373  ETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDS 432

Query: 425  ASSSEVQNGSPMSQTETV--SRSVAPMRGGEITAHWLLTNSTTSADVTGSSASYPEGVNA 482
             +++    GS M+   T     + A   G EIT      + TT+A   GS  +      +
Sbjct: 433  ETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGS 492

Query: 483  SVLTQFSDSTVQSGGSHTALGDR------SYSESSSTSSSESLNSSAPRGER---SIAGI 533
               T ++  +  +  S+T L         S + ++ST  SE+   SA   E    S  G 
Sbjct: 493  ETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGS 552

Query: 534  SYGQVRGTAIEQRTSSDHTDHTYLSSTFTKG-ERALLSITDNSSSSDIVESSTSYIKISN 592
                V  T  E  T S  T     ++T T+G E   +S T   +++D  E S +    ++
Sbjct: 553  ENTTVSTTGSETTTVS--TTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGT--TAAS 608

Query: 593  SSHSEYSSFFHAQTERSNISSYDGEYAQPST---ESPVLHTSNLPSYTPTINMPNTSVVL 649
            ++ SE ++   A +E +  S+ D E    ST   E+    T++  + T +     T+ V 
Sbjct: 609  TAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVS 668

Query: 650  DTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSILPSTRASVHLLKSTSDAS 709
             TD+E    S++ S  + +S+       + +      + +    +T  S+     T   +
Sbjct: 669  TTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSI-----TGSET 723

Query: 710  TPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQSSSTPVLPRARETPVTSFQTSTMTSFMTM 769
            T  S++ S      TT+++    ++  ++  S +T       ET   S + S  TS  T 
Sbjct: 724  TKVSTTGS----ETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTT 779

Query: 770  LHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESST----- 824
               + TA   S  T     + +E+   S +   +E+TK  T +S +    TE+S      
Sbjct: 780  GSETTTASTTSSETTMASIMGSETTMASTIG--SETTKVSTASSKMTTVFTENSETTIAS 837

Query: 825  -------------EQTLPATSTNLAQMSPTFTTTILKTSQ-PLMTTPGTLSSTASLVTGP 870
                          +T+PA++      S T TTT  + S+    +T G+ ++TAS  +  
Sbjct: 838  TTASETTTVSTAGSETIPASTAG----SETTTTTSTEGSETTTASTEGSETTTASTESSE 893

Query: 871  IAVQTTAGKQLSLTHPEILVPQISTEGG----ISTERNRVIVDATTGLIPLTSVPTSAKE 926
                TT G + +           STEG      STE +     +T G   +T+V T+  E
Sbjct: 894  TTTATTIGSETTTA---------STEGSETTTTSTEGSETTTASTEG-SEITTVSTTGSE 943

Query: 927  MTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSATFAVQSSTQSPTTVSSSASV 986
             TT     +E + AS    T  S  TTV +T  +    SA     S T + TT+ S  + 
Sbjct: 944  TTTASTEGSETTTAS----TEGSELTTVSTTGSETITVSAE---GSETTTVTTMGSETTT 996

Query: 987  NSCA 990
             S A
Sbjct: 997  ASTA 1000



 Score =  129 bits (323), Expect = 3e-29
 Identities = 202/902 (22%), Positives = 348/902 (38%), Gaps = 76/902 (8%)

Query: 114  ESNTEAHVENITFYQNQEDFSTVSSKEGVMVQTSGKSHAASDAPENLTLLAETADARGRS 173
            +S T +     +   ++   ++    E   V T+G         ++ T    T  +   +
Sbjct: 387  DSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTA 446

Query: 174  GSSSRTNFTILPV-GYSLEIATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTAS 232
             S++    T     G  + IA+   S++   ++E     + ++   E   A+ T S T +
Sbjct: 447  VSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTT 506

Query: 233  EMGTERAMGLSEEWTVHSQEATTSAWSPSFLPALEMG-ELTTPSRKRNSSGPDLSWLHFY 291
               T   +  +  +T+ S   T S            G E+TT S + + +    +     
Sbjct: 507  ASNT--GLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSET 564

Query: 292  RTAASSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLG 351
             T +++ L   ++S+E +E    ST    ++   T+        T G   T    TVS  
Sbjct: 565  TTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETT----TVSTA 620

Query: 352  PVSKTEGFPKDSRIATTSSSVLLSPSAVESRRNSRVT--GNPGDEEFIEPSTENEFGLTS 409
                T     DS   TTS+S   S +   S  +S  T     G E     +T++E  + S
Sbjct: 621  DSENTTASTADSE--TTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVS 678

Query: 410  LRWQNDSPTFGEHQLASSSEVQNGSPMSQT---ETVSRSVAPMRGGEITAHWLLTNSTTS 466
                    T G  +  +S+E    + +S T    TVS   +      IT       STT 
Sbjct: 679  --------TTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTG 730

Query: 467  ADVTGSSASYPEGVNASVLTQFSDSTVQSGGSHTALGDRSYSE--SSSTSSSESLNSSAP 524
            ++ T +S    E   AS+ T    +T  + GS T       SE  S+ST+ SE+  +S  
Sbjct: 731  SETTTTSTEGSEITTASI-TGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTT 789

Query: 525  RGERSIAGISYGQVR-GTAIEQRTSSDHTDHTYLSSTFTKGERALLSITDNSSSSDIVES 583
              E ++A I   +    + I   T+   T  + +++ FT+     ++ T  S ++ +  +
Sbjct: 790  SSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTA 849

Query: 584  STSYIKISNSSHSEYSSFFHAQTERSNISSYDGEYAQPSTESPVLHTSNLPSYTPTINMP 643
             +  I  S +     ++     +E +  S+   E    STES    T+       TI   
Sbjct: 850  GSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTAT------TIGSE 903

Query: 644  NTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSI------LPSTRA 697
             T+    T+    + +S+  S ++++S+ G  +   S + S    +S         ST  
Sbjct: 904  TTTA--STEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEG 961

Query: 698  SVHLLKSTSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQSSSTPVLPRARETPVTS 757
            S     ST+ + T   S+      ++TT  S   + S      S +T V     ET   S
Sbjct: 962  SELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAG---SETTTVSTAGSETTTAS 1018

Query: 758  FQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPT---ESTKAVTTNSP 814
             + S  T+      SS  ++  + ST   E  IT ++     ++ T   E+T   TT S 
Sbjct: 1019 IEGSETTTV-----SSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSE 1073

Query: 815  LPPSLTESSTEQTLPATSTNLAQMSPT-FTTTILKTSQPLMTTPGTLSSTASLVTGPIAV 873
               + TE S   T+  T +     S     TT + TS    TT  T  S  + V    + 
Sbjct: 1074 TTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSK 1133

Query: 874  QTTAGKQLSLTHPEILVPQISTEGG----ISTERNRVIVDATTGLIPLTSVPTSAKEMTT 929
             TTA                STEG     +ST  +     +TTG   +T+V T+  E TT
Sbjct: 1134 TTTA----------------STEGSEATTVSTTSSETTTASTTG-SEMTTVFTTVSETTT 1176

Query: 930  --KLGVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSATFAVQSSTQSPTTVSSSASVN 987
               +G  A  S A+ S  T+ S + +  +TA     ++ T +   S  +  + S S +  
Sbjct: 1177 VSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNT 1236

Query: 988  SC 989
            +C
Sbjct: 1237 AC 1238



 Score =  118 bits (296), Expect = 3e-26
 Identities = 200/902 (22%), Positives = 348/902 (38%), Gaps = 74/902 (8%)

Query: 134  STVSSKEGVMVQTSG-KSHAASDAPENLTLLAETADARGRSGSSSRTNFTILPVGYSLEI 192
            ST+ S E  M  T G ++   S A   +T +        R+ +      T+   G     
Sbjct: 318  STMGS-ETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTT 376

Query: 193  ATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTASEMGTERAMGLSEEWTVH--S 250
            A+ + S++   ++      ++S+E  E   A    S   SE  T    G SE  TV    
Sbjct: 377  ASIMGSETSTDSTTGSETTTASTEGSETTTA----STEGSEATTVSTTG-SETTTVSITD 431

Query: 251  QEATTSAWSPSFLPAL------------EMGELT---TPSRKRNSSGPDLSWLHFYRTAA 295
             E TT+    S + A+            E  E+T   T   +  ++  + S      TA 
Sbjct: 432  SETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAG 491

Query: 296  SSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVSK 355
            S      ++ SE+T   N  TGL++++V  T      T  T+G   T  S T S      
Sbjct: 492  SETKTAYTTGSETTTASN--TGLETTTVF-TIGSDTTTASTEGSETTAVSATGSEMTTVS 548

Query: 356  TEGFPKDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQND 415
            TEG    +   T S +  +S + +E+   S         E  E +T +  G  +     +
Sbjct: 549  TEGSENTTVSTTGSETTTVSTTGLETTTTST--------EGSEMTTVSTTGAETTTDSTE 600

Query: 416  SPTFGEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADVTGSSAS 475
                     A S      +  S+  T S + +       T     T STTS++ T +S  
Sbjct: 601  GSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTE 660

Query: 476  YPEGVNASVLTQFSDSTVQSGGSHTALGDRSYSESSSTSSSESLNSSAPRGER----SIA 531
              E    S  T    + V + GS   +     SE+++ S++ S  + +  G      SI 
Sbjct: 661  GSETTTVST-TDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSIT 719

Query: 532  GISYGQVRGTAIEQRTSSDHTDHTYLSS--------TFTKGERALLSITDNS--SSSDIV 581
            G    +V  T  E  T+S        +S          T+G     + T+ S  +S+   
Sbjct: 720  GSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTT 779

Query: 582  ESSTSYIKISNSSHSEYSSFFHAQTERSNISSYDGEYAQPSTESPVLHTSNLPSYTPTIN 641
             S T+    ++S  +  S      T  S I S   + +  S++   + T N  +   +  
Sbjct: 780  GSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTT 839

Query: 642  MPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSILPS-TRASVH 700
               T+ V    +E +  S++ S +++++S+ G      S   S    +S   S T  +  
Sbjct: 840  ASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATT 899

Query: 701  LLKSTSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQ--SSSTPVLPRARETPVTSF 758
            +   T+ AST  S + +       T+T++      TT+    S +T       ET   S 
Sbjct: 900  IGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAST 959

Query: 759  QTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPS 818
            + S +T+  T    S+T  + ++ +         S++ +  +  +E+T   T  S    +
Sbjct: 960  EGSELTTVSTT--GSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTA 1017

Query: 819  LTESSTEQTLPATSTNLAQMSPTFTTTILKTSQPLMTTPGTLSSTASLVTGPIAVQTTAG 878
              E S   T+ +T +    +S T T T + +++   TT  T+++  S  T   AV TT  
Sbjct: 1018 SIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETT--TVTTAGSETT---AVYTTGS 1072

Query: 879  KQLSLTHPEILVPQISTEGGISTERNRVIVDATTGLIP---LTSVPTSAKEMTTKLGVTA 935
            +  + +        +ST G  +T  +   ++ TT        T+  T+  E TT     +
Sbjct: 1073 ETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGS 1132

Query: 936  EYSPASRSLGTSPSPQTTVVSTAEDLAPKSAT-------FAVQSSTQSPTTVSSSASVNS 988
            + + AS    T  S  TTV +T+ +    S T       F   S T + +T+ S A+ +S
Sbjct: 1133 KTTTAS----TEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSS 1188

Query: 989  CA 990
             A
Sbjct: 1189 AA 1190



 Score =  110 bits (274), Expect = 1e-23
 Identities = 205/949 (21%), Positives = 368/949 (38%), Gaps = 111/949 (11%)

Query: 124  ITFYQNQEDFSTVSSKEGVMVQTSGKSHAASDAPENLTLLAETADARGRSGSSSRTNFTI 183
            IT     +  +T +S EG   +T+  + A S+     T  +ET  A   +G  + T FTI
Sbjct: 464  ITIASTSDSETTTASTEGS--ETTTVTTAGSETKTAYTTGSETTTA-SNTGLETTTVFTI 520

Query: 184  LPVGYSLEIATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTASEMGTERAMGLS 243
               G     A+   S++  +++    + + S+E  E      T S T SE  T    GL 
Sbjct: 521  ---GSDTTTASTEGSETTAVSATGSEMTTVSTEGSENT----TVSTTGSETTTVSTTGLE 573

Query: 244  EEWTVH--SQEATTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASSPLLD 301
               T    S+  T S            G  TT +    S    +S      T AS+   +
Sbjct: 574  TTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSE 633

Query: 302  LSSSSES-TEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVSKTEGFP 360
             +S+S + +E    ST    ++ + T+     TV T     T+ S T S   ++ TEG  
Sbjct: 634  TTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSE 693

Query: 361  ----------------------------KDSRIATTSSSVLLSPSAVESRRNSRVTGNPG 392
                                        + ++++TT S    + +       + +TG+  
Sbjct: 694  TTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSET 753

Query: 393  DEEFIEPSTENEFGLTSLRWQNDSPTFGEHQLAS--SSEVQNGSPMSQTETVSRSVAPMR 450
                 E S             + S T  E   AS  SSE    S M    T++ ++    
Sbjct: 754  TTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSET 813

Query: 451  GGEITAHWLLTN-----------STTSADVTGSSASYPEGVNASVLTQFSDSTVQSGGSH 499
                TA   +T            STT+++ T  S +  E + AS     + +T  + GS 
Sbjct: 814  TKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSE 873

Query: 500  TALGDRSYSESS--STSSSESLNSSAPRGERSIAGISYGQVRGTAIE-QRTSSDHTDHTY 556
            T       SE++  ST SSE+  ++    E + A     +   T+ E   T++  T+ + 
Sbjct: 874  TTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSE 933

Query: 557  LSSTFTKGERALLSITDNSSSSDIVESSTSYIKISNSSHSEYSSFFHAQTERSNISSYDG 616
            +++  T G     + T+ S ++      +    +S +  SE  +     +E + +++   
Sbjct: 934  ITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTG-SETITVSAEGSETTTVTTMGS 992

Query: 617  EYAQPST---ESPVLHTSNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSG 673
            E    ST   E+  + T+   + T +I    T+ V  T +E  + S++ + ++ +S+   
Sbjct: 993  ETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGS 1052

Query: 674  PPLPLPSV-SQSHHLFSS----ILPSTRASVHLLKSTSDASTPWSSSPSPLPVSLTTS-- 726
                + +  S++  ++++       ST  S     ST+ + T  +S+      +++TS  
Sbjct: 1053 ETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGS 1112

Query: 727  --TSAPLSVSQTTLPQ-------------SSSTPVLPRARETPVTSFQTSTMTSFMTMLH 771
              T+A  + S+TT                S +T V   + ET   S   S MT+  T + 
Sbjct: 1113 GTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVS 1172

Query: 772  SSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESSTEQTLPAT 831
             + T      ST   E   + +      +  TE ++  TT S      T +ST  +   T
Sbjct: 1173 ETTTV-----STIGSEATTSSAAGSEATTTSTEGSE-TTTASTAGSETTTASTAGSETTT 1226

Query: 832  STNLAQMSPTFTTTILKTSQPLMTTPGTLSSTASLVTGPIAVQTTAGKQ---LSLTHPEI 888
            ++     + T  TT  +TS P  ++ G+ ++TA ++     + +TA  +    SLT  E 
Sbjct: 1227 ASTSGSETNTACTTGSETSTP--SSAGSETNTAFIIGSETTIASTASLEPTATSLTGSET 1284

Query: 889  LVPQISTEGGIS-----TERNRVIVDAT-TGLIPLTSVPTSAKEMT-TKLGVTAEYSPAS 941
                I+  G  +     +    V+  AT   + P+T+ P S    T T+L        AS
Sbjct: 1285 TTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRL-------TAS 1337

Query: 942  RSLGTSPSPQTTVVSTAEDLAPKSA--TFAVQSSTQSPTTVSSSASVNS 988
             S+  +P    T  S A    P     T  + +ST   ++ +S+  V +
Sbjct: 1338 SSVTMAPGMDFT-ASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRT 1385



 Score =  106 bits (265), Expect = 1e-22
 Identities = 184/857 (21%), Positives = 340/857 (39%), Gaps = 127/857 (14%)

Query: 230 TASEMGTERAMGLSEEWTVHSQEATTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLH 289
           TAS M +E  +  +      +   T S  +   + A E    +T   +  +  P  S   
Sbjct: 18  TASSMSSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTT 77

Query: 290 FYRTAASSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVS 349
               + S      ++ SE+T   +  +G  ++S++ +++    T+ T G   T  S+T +
Sbjct: 78  IVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSES----TISTAGSETTTVSITGT 133

Query: 350 LGPVSKTEGFPKDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTS 409
              +    G    +   T+S + + S +  E+   S V    G E     + ++E    S
Sbjct: 134 ETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTV----GSETTTAYTADSETTAAS 189

Query: 410 LRWQNDSPTFGEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADV 469
                 +  F     A S  +   +  S+T TVS +     G E T     T STT ++ 
Sbjct: 190 TTGSEMTTVF----TAGSETITPSTAGSETTTVSTA-----GSETT-----TVSTTGSET 235

Query: 470 TGSSASYPEGVNAS--------VLTQFSDSTVQSGGS------------HTALGDRSYSE 509
           T +S ++ E   AS        V T  S++TV + GS            +TA  + S + 
Sbjct: 236 TTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTT 295

Query: 510 SSSTSSSESLNSSAPRGERSIAGISYGQ-VRGTAIEQRTSSDHTDHTYLSSTFTKGERAL 568
           ++ST+  E+  +S    E ++A     +    + I   T+   T  + +++ F  G   +
Sbjct: 296 TASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETI 355

Query: 569 LSITDNSSSSDIVESSTSYIKISNSSHSEYSSFFHAQTERSNISSYDGEYAQPSTE-SPV 627
            + T  S ++  V ++ S    ++   SE S+     +E +  S+   E    STE S  
Sbjct: 356 RASTVGSETT-TVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEA 414

Query: 628 LHTSNLPSYTPTINMPNT---------------------SVVLDTDAEFVSDSSSSSSSS 666
              S   S T T+++ ++                     +    T+   ++ +S+S S +
Sbjct: 415 TTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSET 474

Query: 667 SSSSSSGPPLPLPSV--SQSHHLFSSILPSTRASVHLLKST------SDASTPWSSSPSP 718
           +++S+ G      +   S++   +++   +T AS   L++T      SD +T  +     
Sbjct: 475 TTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSET 534

Query: 719 LPVSLTTSTSAPLSV---SQTTLPQ--SSSTPVLPRARETPVTSFQTSTMTSFMT----- 768
             VS T S    +S      TT+    S +T V     ET  TS + S MT+  T     
Sbjct: 535 TAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAET 594

Query: 769 -------------MLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPL 815
                            S+T  + +  + +      +S++ S  +  +E+T A TT+S  
Sbjct: 595 TTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSET 654

Query: 816 PPSLTESSTEQTLPATSTNLAQMSPT------------FTTTILKT-SQPLMTTPGTLSS 862
             + TE S   T+  T +    +S T             TTT+  T S+  ++T G+ ++
Sbjct: 655 TTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTT 714

Query: 863 TASLVTGPIAVQTTAGKQLSLTH---PEILVPQI--------STEGG----ISTERNRVI 907
           T S+        +T G + + T     EI    I        STEG      STE +   
Sbjct: 715 TVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETT 774

Query: 908 VDATTGLIPLTSVPTSAKEMTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSAT 967
             +TTG    T+  TS++  TT   +    +  + ++G+  +  +T  S    +  +++ 
Sbjct: 775 SASTTGSETTTASTTSSE--TTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSE 832

Query: 968 FAVQSSTQSPTTVSSSA 984
             + S+T S TT  S+A
Sbjct: 833 TTIASTTASETTTVSTA 849



 Score = 98.2 bits (243), Expect = 5e-20
 Identities = 146/628 (23%), Positives = 247/628 (39%), Gaps = 75/628 (11%)

Query: 426 SSSEVQNGSPMSQTETVS------RSVAPMRGGEITAHWLLTNSTTSADVTGSSASYPE- 478
           + S+V   S MS   TV+       + A   G E T   +  + TT+A   GS  + P  
Sbjct: 12  ADSKVITASSMSSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSP 71

Query: 479 --------GVNASVLTQFS-----DSTVQSGGSHTALGDRSYSESS-STSSSESLNSSAP 524
                    ++ S +T  S     ++TV S GS T     + SES+ ST+ SE+      
Sbjct: 72  TGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSESTISTAGSETTTV--- 128

Query: 525 RGERSIAGISYGQVRGTAIEQRTSSDHTDHTYLSSTFTKGERALLSITDNSSSSDIVESS 584
               SI G     V     E  T+S  +  T ++ST       + ++   ++++   +S 
Sbjct: 129 ----SITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSE 184

Query: 585 TSYIKISNSSHSEYSSFFHAQTERSNISSYDGEYAQPST---ESPVLHTSNLPSYTPTIN 641
           T+    ++++ SE ++ F A +E    S+   E    ST   E+  + T+   + T +  
Sbjct: 185 TT---AASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTA 241

Query: 642 MPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSILPSTRASVHL 701
              T+      +E    S++ S ++ S++ S         S+++  F+    +T AS   
Sbjct: 242 HSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTG 301

Query: 702 LKSTSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQSSS--TPVLPRARETPVTSFQ 759
            ++T+ AST  S       +   T+ ++ +    T +  +SS  T V     ET   S  
Sbjct: 302 FETTA-ASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTV 360

Query: 760 TSTMTSFMTMLHSSQTADL-----KSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSP 814
            S  T+  T    + TA +      + ST   E     ++     +  TE ++A T ++ 
Sbjct: 361 GSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTT 420

Query: 815 LPPSLTESSTEQTLPATSTNLAQMSPTFTT--------------TILKTSQPLMTTPGTL 860
              + T S T+     T T  ++M+   TT              TI  TS    TT  T 
Sbjct: 421 GSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTE 480

Query: 861 SSTASLVT----GPIAVQTTAGKQLSLTHPEILVPQISTEGG----ISTERNRVIVDATT 912
            S  + VT          TT  +  + ++  +    + T G      STE +     + T
Sbjct: 481 GSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSAT 540

Query: 913 GLIPLTSVPTSAKEMTTKLGVTAEYSPAS------RSLGTSPSPQTTV----VSTAEDLA 962
           G   +T+V T   E TT     +E +  S       +  T  S  TTV      T  D  
Sbjct: 541 G-SEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDST 599

Query: 963 PKSATFAVQSSTQSPTTVSSSASVNSCA 990
             S T A  ++    TTVS++ S N+ A
Sbjct: 600 EGSGTTAASTAGSETTTVSTADSENTTA 627



 Score = 75.1 bits (183), Expect = 4e-13
 Identities = 146/624 (23%), Positives = 255/624 (40%), Gaps = 74/624 (11%)

Query: 116  NTEAHVENITFYQNQEDFSTVSS--KEGVMVQTSGK---SHAASDAPENLTLLAETADAR 170
            N+E  + + T      + +TVS+   E +   T+G    +  +++  E  T   E ++  
Sbjct: 830  NSETTIASTT----ASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETT 885

Query: 171  GRSGSSSRTNFTILPVGYSLEIATALTSQSGNLASESLHLPSSSSEFDE--RIAAFQTKS 228
              S  SS T  T   +G     A+   S++   ++E     ++S+E  E   ++   +++
Sbjct: 886  TASTESSETT-TATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSET 944

Query: 229  GTASEMGTERAMGLSEEW------TVHSQEATTSAWSPSFLPALEMGELTTPSRKRNSSG 282
             TAS  G+E     +E        T  S+  T SA          MG  TT +    S  
Sbjct: 945  TTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSET 1004

Query: 283  PDLSWLHFYRTAASSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRT 342
              +S      TA S         SE+T    +STG ++++VS T T    T  T+G   T
Sbjct: 1005 TTVS------TAGSETTTASIEGSETTTV--SSTGSETTTVSTTGTETTITS-TEGSETT 1055

Query: 343  LRSLTVSLGPVSKTEGFPKDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTE 402
                TV+      T  +   S   TTS+      + V +  +   T +  D E    ST 
Sbjct: 1056 ----TVTTAGSETTAVYTTGSETTTTSTEGS-ETTTVSTTGSETTTASTADLETTTVSTS 1110

Query: 403  NEFGLTSLRWQNDSPTF---GEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWL 459
                 T+    +++ T    G     +S+E    + +S T + + + A   G E+T  + 
Sbjct: 1111 GSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSET-TTASTTGSEMTTVFT 1169

Query: 460  LTNSTTS-----ADVTGSSASYPEGVNASVLTQFSDSTVQS-GGSHTALGDRSYSESSST 513
              + TT+     ++ T SSA+  E    S  T+ S++T  S  GS T     + SE+++ 
Sbjct: 1170 TVSETTTVSTIGSEATTSSAAGSEATTTS--TEGSETTTASTAGSETTTASTAGSETTTA 1227

Query: 514  SSSES-LNSSAPRGERSIAGISYGQVRGTAI---EQRTSSDHTDHTYLSSTFTKGERALL 569
            S+S S  N++   G  +    S G    TA     + T +        +++ T  E   +
Sbjct: 1228 STSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTV 1287

Query: 570  SIT-DNSSSSDIVESSTSYI----------KISNSSHSEYSSFFHAQTERSNIS-----S 613
            SIT   ++++    SST+++           I+N+  S   +     T  S+++      
Sbjct: 1288 SITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMD 1347

Query: 614  YDGEYAQPSTESPVLHTSNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSSSSSS--S 671
            +    A  +    VL+TS L   T T+   +T     T A  V  ++ S+   +SS+   
Sbjct: 1348 FTASAASHTVPGIVLNTSGLG--TSTMGASST-----TSAHGVRTTTGSTREPTSSTFQE 1400

Query: 672  SGP-PLPLPSVSQSHHLFSSILPS 694
            +GP  +   +VS SH   + I PS
Sbjct: 1401 TGPVSMGTNTVSMSHTPTNVIKPS 1424



 Score = 63.9 bits (154), Expect = 1e-09
 Identities = 108/556 (19%), Positives = 201/556 (36%), Gaps = 47/556 (8%)

Query: 653  AEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSILPSTRASVHLLKSTSDASTPW 712
            +E  + S++ S   ++SS S      P+   +    S+    T   +     T+ AST  
Sbjct: 4    SEATTTSTADSKVITASSMSSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAG 63

Query: 713  SSSPSPLPVS-------------LTTSTSAPLSVSQTTLPQSSSTPVLPRARETPVTSFQ 759
            S + +P P                TTST+   + + ++    ++T  +  +  T  T+  
Sbjct: 64   SETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSESTISTAGS 123

Query: 760  TST---MTSFMTMLHSSQTADLKSQSTPHQEKVITE---SKSPSLVSLPTESTKAVTTNS 813
             +T   +T   T + S+  ++  + ST   E  +T    S++ ++ ++ +E+T A T +S
Sbjct: 124  ETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADS 183

Query: 814  PLPPSLTESSTEQTL----PATSTNLAQMSPTFTTTILKTSQPLMTTPGTLSSTASLVTG 869
                + T  S   T+      T T     S T T +   +    ++T G+ ++TAS    
Sbjct: 184  ETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHS 243

Query: 870  PIAVQTTAGKQLSLTHPEILVPQISTEGGIST-------ERNRVIV-DATTGLIPLTSVP 921
                 +T G + +          +ST G  +T       E N     D+ T     T   
Sbjct: 244  ETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFE 303

Query: 922  TSAKEMTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAED-----LAPKSATFAVQSSTQS 976
            T+A   T      A    +  ++ ++  P+TT VSTA        A  S T    +    
Sbjct: 304  TTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSE 363

Query: 977  PTTVSSSASVNSCAVNPCLHNGECVADNTSRGYHCRCPPSWQGDDCSVDVNE-----CLS 1031
             TTVS++ S  + A    +   E   D+T+         S +G + +    E      +S
Sbjct: 364  TTTVSTTGSETTTA---SIMGSETSTDSTTGSE--TTTASTEGSETTTASTEGSEATTVS 418

Query: 1032 NPCPSTAMCNNTQGSFICKCPVGYQLEKGICNLVRTFVTEFKLKRTFLNTTVEKHSDLQE 1091
                 T   + T       C  G ++      +  T     +     + +T +  +    
Sbjct: 419  TTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTAS 478

Query: 1092 VENEITKTLNMCFSALPSYIRSTVHASRESNAVVISLQTTFSLASNVTLFDLADRMQKCV 1151
             E   T T+    S   +   +    +  SN   +   T F++ S+ T           V
Sbjct: 479  TEGSETTTVTTAGSETKTAYTTGSETTTASN-TGLETTTVFTIGSDTTTASTEGSETTAV 537

Query: 1152 NSCKSSAEVCQLLGSQ 1167
            ++  S        GS+
Sbjct: 538  SATGSEMTTVSTEGSE 553


>gi|239740777 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1612

 Score =  134 bits (336), Expect = 8e-31
 Identities = 217/904 (24%), Positives = 370/904 (40%), Gaps = 98/904 (10%)

Query: 134 STVSSKEGVMVQTSGKSHAASDAPENLTLLAETAD----ARGRSGSSSRTNFTILPVGYS 189
           ++ +S E  +  T+G          + T  A TAD    A   +GS   T FT      +
Sbjct: 127 NSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETIT 186

Query: 190 LEIATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTASEMGTERAMGLSEEWTVH 249
              A + T+      SE+  + ++ SE      A  +++  AS MG+E     ++  T  
Sbjct: 187 PSTAGSETTTVSTAGSETTTVSTTGSETTTASTA-HSETTAASTMGSE----TTKVSTAG 241

Query: 250 SQEATTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASS----PLLDLSSS 305
           S+   ++A S +   + E  E T  +   +S     S   F  TAAS+    P +  +  
Sbjct: 242 SETTVSTAGSETTAASTEDSE-TNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMG 300

Query: 306 SESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVSKTEGFPKDSRI 365
           SE+T  + ++ G +++ VS T +  V TVF   G  T+R+ TV  G  + T      +  
Sbjct: 301 SETT--MASTIGPETTKVS-TASSEVTTVFA-AGSETIRASTV--GSETTT---VSTTGS 351

Query: 366 ATTSSSVLLSPSAVESRRNSR-VTGNPGDEEFIEPSTENEFGLTSLRWQNDSPTFGEHQL 424
            TT++S++ S ++ +S   S   T +    E    STE     T     +++ T      
Sbjct: 352 ETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDS 411

Query: 425 ASSSEVQNGSPMSQTETV--SRSVAPMRGGEITAHWLLTNSTTSADVTGSSASYPEGVNA 482
            +++    GS M+   T     + A   G EIT      + TT+A   GS  +      +
Sbjct: 412 ETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGS 471

Query: 483 SVLTQFSDSTVQSGGSHTALGDR------SYSESSSTSSSESLNSSAPRGER---SIAGI 533
              T ++  +  +  S+T L         S + ++ST  SE+   SA   E    S  G 
Sbjct: 472 ETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGS 531

Query: 534 SYGQVRGTAIEQRTSSDHTDHTYLSSTFTKG-ERALLSITDNSSSSDIVESSTSYIKISN 592
               V  T  E  T S  T     ++T T+G E   +S T   +++D  E S +    ++
Sbjct: 532 ENTTVSTTGSETTTVS--TTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGT--TAAS 587

Query: 593 SSHSEYSSFFHAQTERSNISSYDGEYAQPST---ESPVLHTSNLPSYTPTINMPNTSVVL 649
           ++ SE ++   A +E +  S+ D E    ST   E+    T++  + T +     T+ V 
Sbjct: 588 TAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVS 647

Query: 650 DTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSILPSTRASVHLLKSTSDAS 709
            TD+E    S++ S  + +S+       + +      + +    +T  S+     T   +
Sbjct: 648 TTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSI-----TGSET 702

Query: 710 TPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQSSSTPVLPRARETPVTSFQTSTMTSFMTM 769
           T  S++ S      TT+++    ++  ++  S +T       ET   S + S  TS  T 
Sbjct: 703 TKVSTTGS----ETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTT 758

Query: 770 LHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESST----- 824
              + TA   S  T     + +E+   S +   +E+TK  T +S +    TE+S      
Sbjct: 759 GSETTTASTTSSETTMASIMGSETTMASTIG--SETTKVSTASSKMTTVFTENSETTIAS 816

Query: 825 -------------EQTLPATSTNLAQMSPTFTTTILKTSQ-PLMTTPGTLSSTASLVTGP 870
                         +T+PA++      S T TTT  + S+    +T G+ ++TAS  +  
Sbjct: 817 TTASETTTVSTAGSETIPASTAG----SETTTTTSTEGSETTTASTEGSETTTASTESSE 872

Query: 871 IAVQTTAGKQLSLTHPEILVPQISTEGG----ISTERNRVIVDATTGLIPLTSVPTSAKE 926
               TT G + +           STEG      STE +     +T G   +T+V T+  E
Sbjct: 873 TTTATTIGSETTTA---------STEGSETTTTSTEGSETTTASTEG-SEITTVSTTGSE 922

Query: 927 MTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSATFAVQSSTQSPTTVSSSASV 986
            TT     +E + AS    T  S  TTV +T  +    SA     S T + TT+ S  + 
Sbjct: 923 TTTASTEGSETTTAS----TEGSELTTVSTTGSETITVSAE---GSETTTVTTMGSETTT 975

Query: 987 NSCA 990
            S A
Sbjct: 976 ASTA 979



 Score =  129 bits (323), Expect = 3e-29
 Identities = 202/902 (22%), Positives = 348/902 (38%), Gaps = 76/902 (8%)

Query: 114  ESNTEAHVENITFYQNQEDFSTVSSKEGVMVQTSGKSHAASDAPENLTLLAETADARGRS 173
            +S T +     +   ++   ++    E   V T+G         ++ T    T  +   +
Sbjct: 366  DSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTA 425

Query: 174  GSSSRTNFTILPV-GYSLEIATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTAS 232
             S++    T     G  + IA+   S++   ++E     + ++   E   A+ T S T +
Sbjct: 426  VSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTT 485

Query: 233  EMGTERAMGLSEEWTVHSQEATTSAWSPSFLPALEMG-ELTTPSRKRNSSGPDLSWLHFY 291
               T   +  +  +T+ S   T S            G E+TT S + + +    +     
Sbjct: 486  ASNT--GLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSET 543

Query: 292  RTAASSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLG 351
             T +++ L   ++S+E +E    ST    ++   T+        T G   T    TVS  
Sbjct: 544  TTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETT----TVSTA 599

Query: 352  PVSKTEGFPKDSRIATTSSSVLLSPSAVESRRNSRVT--GNPGDEEFIEPSTENEFGLTS 409
                T     DS   TTS+S   S +   S  +S  T     G E     +T++E  + S
Sbjct: 600  DSENTTASTADSE--TTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVS 657

Query: 410  LRWQNDSPTFGEHQLASSSEVQNGSPMSQT---ETVSRSVAPMRGGEITAHWLLTNSTTS 466
                    T G  +  +S+E    + +S T    TVS   +      IT       STT 
Sbjct: 658  --------TTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTG 709

Query: 467  ADVTGSSASYPEGVNASVLTQFSDSTVQSGGSHTALGDRSYSE--SSSTSSSESLNSSAP 524
            ++ T +S    E   AS+ T    +T  + GS T       SE  S+ST+ SE+  +S  
Sbjct: 710  SETTTTSTEGSEITTASI-TGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTT 768

Query: 525  RGERSIAGISYGQVR-GTAIEQRTSSDHTDHTYLSSTFTKGERALLSITDNSSSSDIVES 583
              E ++A I   +    + I   T+   T  + +++ FT+     ++ T  S ++ +  +
Sbjct: 769  SSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTA 828

Query: 584  STSYIKISNSSHSEYSSFFHAQTERSNISSYDGEYAQPSTESPVLHTSNLPSYTPTINMP 643
             +  I  S +     ++     +E +  S+   E    STES    T+       TI   
Sbjct: 829  GSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTAT------TIGSE 882

Query: 644  NTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSI------LPSTRA 697
             T+    T+    + +S+  S ++++S+ G  +   S + S    +S         ST  
Sbjct: 883  TTTA--STEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEG 940

Query: 698  SVHLLKSTSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQSSSTPVLPRARETPVTS 757
            S     ST+ + T   S+      ++TT  S   + S      S +T V     ET   S
Sbjct: 941  SELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAG---SETTTVSTAGSETTTAS 997

Query: 758  FQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPT---ESTKAVTTNSP 814
             + S  T+      SS  ++  + ST   E  IT ++     ++ T   E+T   TT S 
Sbjct: 998  IEGSETTTV-----SSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSE 1052

Query: 815  LPPSLTESSTEQTLPATSTNLAQMSPT-FTTTILKTSQPLMTTPGTLSSTASLVTGPIAV 873
               + TE S   T+  T +     S     TT + TS    TT  T  S  + V    + 
Sbjct: 1053 TTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSK 1112

Query: 874  QTTAGKQLSLTHPEILVPQISTEGG----ISTERNRVIVDATTGLIPLTSVPTSAKEMTT 929
             TTA                STEG     +ST  +     +TTG   +T+V T+  E TT
Sbjct: 1113 TTTA----------------STEGSEATTVSTTSSETTTASTTG-SEMTTVFTTVSETTT 1155

Query: 930  --KLGVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSATFAVQSSTQSPTTVSSSASVN 987
               +G  A  S A+ S  T+ S + +  +TA     ++ T +   S  +  + S S +  
Sbjct: 1156 VSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNT 1215

Query: 988  SC 989
            +C
Sbjct: 1216 AC 1217



 Score =  118 bits (296), Expect = 3e-26
 Identities = 200/902 (22%), Positives = 348/902 (38%), Gaps = 74/902 (8%)

Query: 134  STVSSKEGVMVQTSG-KSHAASDAPENLTLLAETADARGRSGSSSRTNFTILPVGYSLEI 192
            ST+ S E  M  T G ++   S A   +T +        R+ +      T+   G     
Sbjct: 297  STMGS-ETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTT 355

Query: 193  ATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTASEMGTERAMGLSEEWTVH--S 250
            A+ + S++   ++      ++S+E  E   A    S   SE  T    G SE  TV    
Sbjct: 356  ASIMGSETSTDSTTGSETTTASTEGSETTTA----STEGSEATTVSTTG-SETTTVSITD 410

Query: 251  QEATTSAWSPSFLPAL------------EMGELT---TPSRKRNSSGPDLSWLHFYRTAA 295
             E TT+    S + A+            E  E+T   T   +  ++  + S      TA 
Sbjct: 411  SETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAG 470

Query: 296  SSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVSK 355
            S      ++ SE+T   N  TGL++++V  T      T  T+G   T  S T S      
Sbjct: 471  SETKTAYTTGSETTTASN--TGLETTTVF-TIGSDTTTASTEGSETTAVSATGSEMTTVS 527

Query: 356  TEGFPKDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQND 415
            TEG    +   T S +  +S + +E+   S         E  E +T +  G  +     +
Sbjct: 528  TEGSENTTVSTTGSETTTVSTTGLETTTTST--------EGSEMTTVSTTGAETTTDSTE 579

Query: 416  SPTFGEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADVTGSSAS 475
                     A S      +  S+  T S + +       T     T STTS++ T +S  
Sbjct: 580  GSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTE 639

Query: 476  YPEGVNASVLTQFSDSTVQSGGSHTALGDRSYSESSSTSSSESLNSSAPRGER----SIA 531
              E    S  T    + V + GS   +     SE+++ S++ S  + +  G      SI 
Sbjct: 640  GSETTTVST-TDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSIT 698

Query: 532  GISYGQVRGTAIEQRTSSDHTDHTYLSS--------TFTKGERALLSITDNS--SSSDIV 581
            G    +V  T  E  T+S        +S          T+G     + T+ S  +S+   
Sbjct: 699  GSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTT 758

Query: 582  ESSTSYIKISNSSHSEYSSFFHAQTERSNISSYDGEYAQPSTESPVLHTSNLPSYTPTIN 641
             S T+    ++S  +  S      T  S I S   + +  S++   + T N  +   +  
Sbjct: 759  GSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTT 818

Query: 642  MPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSILPS-TRASVH 700
               T+ V    +E +  S++ S +++++S+ G      S   S    +S   S T  +  
Sbjct: 819  ASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATT 878

Query: 701  LLKSTSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQ--SSSTPVLPRARETPVTSF 758
            +   T+ AST  S + +       T+T++      TT+    S +T       ET   S 
Sbjct: 879  IGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAST 938

Query: 759  QTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPS 818
            + S +T+  T    S+T  + ++ +         S++ +  +  +E+T   T  S    +
Sbjct: 939  EGSELTTVSTT--GSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTA 996

Query: 819  LTESSTEQTLPATSTNLAQMSPTFTTTILKTSQPLMTTPGTLSSTASLVTGPIAVQTTAG 878
              E S   T+ +T +    +S T T T + +++   TT  T+++  S  T   AV TT  
Sbjct: 997  SIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETT--TVTTAGSETT---AVYTTGS 1051

Query: 879  KQLSLTHPEILVPQISTEGGISTERNRVIVDATTGLIP---LTSVPTSAKEMTTKLGVTA 935
            +  + +        +ST G  +T  +   ++ TT        T+  T+  E TT     +
Sbjct: 1052 ETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGS 1111

Query: 936  EYSPASRSLGTSPSPQTTVVSTAEDLAPKSAT-------FAVQSSTQSPTTVSSSASVNS 988
            + + AS    T  S  TTV +T+ +    S T       F   S T + +T+ S A+ +S
Sbjct: 1112 KTTTAS----TEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSS 1167

Query: 989  CA 990
             A
Sbjct: 1168 AA 1169



 Score =  111 bits (278), Expect = 4e-24
 Identities = 201/949 (21%), Positives = 373/949 (39%), Gaps = 110/949 (11%)

Query: 124  ITFYQNQEDFSTVSSKEGVMVQTSGKSHAASDAPENLTLLAETADARGRSGSSSRTNFTI 183
            IT     +  +T +S EG   +T+  + A S+     T  +ET  A   +G  + T FTI
Sbjct: 443  ITIASTSDSETTTASTEGS--ETTTVTTAGSETKTAYTTGSETTTA-SNTGLETTTVFTI 499

Query: 184  LPVGYSLEIATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTASEMGTERAMGLS 243
               G     A+   S++  +++    + + S+E  E      T S T SE  T    GL 
Sbjct: 500  ---GSDTTTASTEGSETTAVSATGSEMTTVSTEGSENT----TVSTTGSETTTVSTTGLE 552

Query: 244  EEWTVH--SQEATTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASSPLLD 301
               T    S+  T S            G  TT +    S    +S      T AS+   +
Sbjct: 553  TTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSE 612

Query: 302  LSSSSES-TEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVSKTEGFP 360
             +S+S + +E    ST    ++ + T+     TV T     T+ S T S   ++ TEG  
Sbjct: 613  TTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSE 672

Query: 361  ----------------------------KDSRIATTSSSVLLSPSAVESRRNSRVTGNPG 392
                                        + ++++TT S    + +       + +TG+  
Sbjct: 673  TTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSET 732

Query: 393  DEEFIEPSTENEFGLTSLRWQNDSPTFGEHQLAS--SSEVQNGSPMSQTETVSRSVAPMR 450
                 E S             + S T  E   AS  SSE    S M    T++ ++    
Sbjct: 733  TTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSET 792

Query: 451  GGEITAHWLLTN-----------STTSADVTGSSASYPEGVNASVLTQFSDSTVQSGGSH 499
                TA   +T            STT+++ T  S +  E + AS     + +T  + GS 
Sbjct: 793  TKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSE 852

Query: 500  TALGDRSYSESS--STSSSESLNSSAPRGERSIAGISYGQVRGTAIE-QRTSSDHTDHTY 556
            T       SE++  ST SSE+  ++    E + A     +   T+ E   T++  T+ + 
Sbjct: 853  TTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSE 912

Query: 557  LSSTFTKGERALLSITDNSSSSDIVESSTSYIKISNSSHSEYSSFFHAQTERSNISSYDG 616
            +++  T G     + T+ S ++      +    +S +  SE  +     +E + +++   
Sbjct: 913  ITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTG-SETITVSAEGSETTTVTTMGS 971

Query: 617  EYAQPST---ESPVLHTSNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSG 673
            E    ST   E+  + T+   + T +I    T+ V  T +E  + S++ + ++ +S+   
Sbjct: 972  ETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGS 1031

Query: 674  PPLPLPSV-SQSHHLFSS----ILPSTRASVHLLKSTSDASTPWSSSPSPLPVSLTTS-- 726
                + +  S++  ++++       ST  S     ST+ + T  +S+      +++TS  
Sbjct: 1032 ETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGS 1091

Query: 727  --TSAPLSVSQTTLPQ-------------SSSTPVLPRARETPVTSFQTSTMTSFMTMLH 771
              T+A  + S+TT                S +T V   + ET   S   S MT+  T + 
Sbjct: 1092 GTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVS 1151

Query: 772  SSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESSTEQTLPAT 831
             + T      ST   E   + +      +  TE ++  TT S      T +ST  +   T
Sbjct: 1152 ETTTV-----STIGSEATTSSAAGSEATTTSTEGSE-TTTASTAGSETTTASTAGSETTT 1205

Query: 832  STNLAQMSPTFTTTILKTSQPLMTTPGTLSSTASLVTGPIAVQTTAGKQ---LSLTHPEI 888
            ++     + T  TT  +TS P  ++ G+ ++TA ++     + +TA  +    SLT  E 
Sbjct: 1206 ASTSGSETNTACTTGSETSTP--SSAGSETNTAFIIGSETTIASTASLEPTATSLTGSET 1263

Query: 889  LVPQISTEGGISTERNRVIVDATTGLIPLTSVPTSAKEMTTKLGVTAEYSPASRSLGTSP 948
                I+  G  +         A+T +   T V T A +++ +  +T      +R+ GT P
Sbjct: 1264 TTVSITASGATA---------ASTTVSSTTFVLTKATDVSIQ-PITNTPMSGTRTTGTRP 1313

Query: 949  SPQTTV-VSTAEDLAPKSATFAV-----QSSTQSPTTVSSSASVNSCAV 991
            +  ++V ++   D    +A+  V      +S    +T+ +S++ ++  V
Sbjct: 1314 TASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGV 1362



 Score =  105 bits (261), Expect = 4e-22
 Identities = 191/857 (22%), Positives = 342/857 (39%), Gaps = 147/857 (17%)

Query: 230 TASEMGTERAMGLSEEWTVHSQEATTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLH 289
           TAS  G+E    L     + + E TT++ + S        E TTPS       P  S   
Sbjct: 17  TASTTGSETTTIL-----IKASETTTASTAGS--------ETTTPS-------PTGSQTT 56

Query: 290 FYRTAASSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVS 349
               + S      ++ SE+T   +  +G  ++S++ ++T    TV T G   T  S+T +
Sbjct: 57  IVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSET----TVSTAGSETTTVSITGT 112

Query: 350 LGPVSKTEGFPKDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTS 409
              +    G    +   T+S + + S +  E+   S V    G E     + ++E    S
Sbjct: 113 ETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTV----GSETTTAYTADSETTAAS 168

Query: 410 LRWQNDSPTFGEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADV 469
                 +  F     A S  +   +  S+T TVS +     G E T     T STT ++ 
Sbjct: 169 TTGSEMTTVF----TAGSETITPSTAGSETTTVSTA-----GSETT-----TVSTTGSET 214

Query: 470 TGSSASYPEGVNAS--------VLTQFSDSTVQSGGS------------HTALGDRSYSE 509
           T +S ++ E   AS        V T  S++TV + GS            +TA  + S + 
Sbjct: 215 TTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTT 274

Query: 510 SSSTSSSESLNSSAPRGERSIAGISYGQ-VRGTAIEQRTSSDHTDHTYLSSTFTKGERAL 568
           ++ST+  E+  +S    E ++A     +    + I   T+   T  + +++ F  G   +
Sbjct: 275 TASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETI 334

Query: 569 LSITDNSSSSDIVESSTSYIKISNSSHSEYSSFFHAQTERSNISSYDGEYAQPSTE-SPV 627
            + T  S ++  V ++ S    ++   SE S+     +E +  S+   E    STE S  
Sbjct: 335 RASTVGSETT-TVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEA 393

Query: 628 LHTSNLPSYTPTINMPNT---------------------SVVLDTDAEFVSDSSSSSSSS 666
              S   S T T+++ ++                     +    T+   ++ +S+S S +
Sbjct: 394 TTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSET 453

Query: 667 SSSSSSGPPLPLPSV--SQSHHLFSSILPSTRASVHLLKST------SDASTPWSSSPSP 718
           +++S+ G      +   S++   +++   +T AS   L++T      SD +T  +     
Sbjct: 454 TTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSET 513

Query: 719 LPVSLTTSTSAPLSV---SQTTLPQ--SSSTPVLPRARETPVTSFQTSTMTSFMT----- 768
             VS T S    +S      TT+    S +T V     ET  TS + S MT+  T     
Sbjct: 514 TAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAET 573

Query: 769 -------------MLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPL 815
                            S+T  + +  + +      +S++ S  +  +E+T A TT+S  
Sbjct: 574 TTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSET 633

Query: 816 PPSLTESSTEQTLPATSTNLAQMSPT------------FTTTILKT-SQPLMTTPGTLSS 862
             + TE S   T+  T +    +S T             TTT+  T S+  ++T G+ ++
Sbjct: 634 TTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTT 693

Query: 863 TASLVTGPIAVQTTAGKQLSLTH---PEILVPQI--------STEGG----ISTERNRVI 907
           T S+        +T G + + T     EI    I        STEG      STE +   
Sbjct: 694 TVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETT 753

Query: 908 VDATTGLIPLTSVPTSAKEMTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSAT 967
             +TTG    T+  TS++  TT   +    +  + ++G+  +  +T  S    +  +++ 
Sbjct: 754 SASTTGSETTTASTTSSE--TTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSE 811

Query: 968 FAVQSSTQSPTTVSSSA 984
             + S+T S TT  S+A
Sbjct: 812 TTIASTTASETTTVSTA 828



 Score = 93.6 bits (231), Expect = 1e-18
 Identities = 138/603 (22%), Positives = 237/603 (39%), Gaps = 69/603 (11%)

Query: 445 SVAPMRGGEITAHWLLTNSTTSADVTGSSASYPE---------GVNASVLTQFS-----D 490
           + A   G E T   +  + TT+A   GS  + P           ++ S +T  S     +
Sbjct: 16  TTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSEN 75

Query: 491 STVQSGGSHTALGDRSYSESS-STSSSESLNSSAPRGERSIAGISYGQVRGTAIEQRTSS 549
           +TV S GS T     + SE++ ST+ SE+          SI G     V     E  T+S
Sbjct: 76  TTVSSAGSGTTTASMAGSETTVSTAGSETTTV-------SITGTETTMVSAMGSETTTNS 128

Query: 550 DHTDHTYLSSTFTKGERALLSITDNSSSSDIVESSTSYIKISNSSHSEYSSFFHAQTERS 609
             +  T ++ST       + ++   ++++   +S T+    ++++ SE ++ F A +E  
Sbjct: 129 TTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETT---AASTTGSEMTTVFTAGSETI 185

Query: 610 NISSYDGEYAQPST---ESPVLHTSNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSS 666
             S+   E    ST   E+  + T+   + T +     T+      +E    S++ S ++
Sbjct: 186 TPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETT 245

Query: 667 SSSSSSGPPLPLPSVSQSHHLFSSILPSTRASVHLLKSTSDASTPWSSSPSPLPVSLTTS 726
            S++ S         S+++  F+    +T AS    ++T+ AST  S       +   T+
Sbjct: 246 VSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTA-ASTTGSEPTMASTMGSETT 304

Query: 727 TSAPLSVSQTTLPQSSS--TPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADL-----K 779
            ++ +    T +  +SS  T V     ET   S   S  T+  T    + TA +      
Sbjct: 305 MASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETS 364

Query: 780 SQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESSTEQTLPATSTNLAQMS 839
           + ST   E     ++     +  TE ++A T ++    + T S T+     T T  ++M+
Sbjct: 365 TDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMT 424

Query: 840 PTFTT--------------TILKTSQPLMTTPGTLSSTASLVT----GPIAVQTTAGKQL 881
              TT              TI  TS    TT  T  S  + VT          TT  +  
Sbjct: 425 AVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETT 484

Query: 882 SLTHPEILVPQISTEGG----ISTERNRVIVDATTGLIPLTSVPTSAKEMTTKLGVTAEY 937
           + ++  +    + T G      STE +     + TG   +T+V T   E TT     +E 
Sbjct: 485 TASNTGLETTTVFTIGSDTTTASTEGSETTAVSATG-SEMTTVSTEGSENTTVSTTGSET 543

Query: 938 SPAS------RSLGTSPSPQTTV----VSTAEDLAPKSATFAVQSSTQSPTTVSSSASVN 987
           +  S       +  T  S  TTV      T  D    S T A  ++    TTVS++ S N
Sbjct: 544 TTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSEN 603

Query: 988 SCA 990
           + A
Sbjct: 604 TTA 606



 Score = 75.5 bits (184), Expect = 3e-13
 Identities = 146/624 (23%), Positives = 255/624 (40%), Gaps = 74/624 (11%)

Query: 116  NTEAHVENITFYQNQEDFSTVSS--KEGVMVQTSGK---SHAASDAPENLTLLAETADAR 170
            N+E  + + T      + +TVS+   E +   T+G    +  +++  E  T   E ++  
Sbjct: 809  NSETTIASTT----ASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETT 864

Query: 171  GRSGSSSRTNFTILPVGYSLEIATALTSQSGNLASESLHLPSSSSEFDE--RIAAFQTKS 228
              S  SS T  T   +G     A+   S++   ++E     ++S+E  E   ++   +++
Sbjct: 865  TASTESSETT-TATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSET 923

Query: 229  GTASEMGTERAMGLSEEW------TVHSQEATTSAWSPSFLPALEMGELTTPSRKRNSSG 282
             TAS  G+E     +E        T  S+  T SA          MG  TT +    S  
Sbjct: 924  TTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSET 983

Query: 283  PDLSWLHFYRTAASSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRT 342
              +S      TA S         SE+T    +STG ++++VS T T    T  T+G   T
Sbjct: 984  TTVS------TAGSETTTASIEGSETTTV--SSTGSETTTVSTTGTETTITS-TEGSETT 1034

Query: 343  LRSLTVSLGPVSKTEGFPKDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTE 402
                TV+      T  +   S   TTS+      + V +  +   T +  D E    ST 
Sbjct: 1035 ----TVTTAGSETTAVYTTGSETTTTSTEGS-ETTTVSTTGSETTTASTADLETTTVSTS 1089

Query: 403  NEFGLTSLRWQNDSPTF---GEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWL 459
                 T+    +++ T    G     +S+E    + +S T + + + A   G E+T  + 
Sbjct: 1090 GSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSET-TTASTTGSEMTTVFT 1148

Query: 460  LTNSTTS-----ADVTGSSASYPEGVNASVLTQFSDSTVQS-GGSHTALGDRSYSESSST 513
              + TT+     ++ T SSA+  E    S  T+ S++T  S  GS T     + SE+++ 
Sbjct: 1149 TVSETTTVSTIGSEATTSSAAGSEATTTS--TEGSETTTASTAGSETTTASTAGSETTTA 1206

Query: 514  SSSES-LNSSAPRGERSIAGISYGQVRGTAI---EQRTSSDHTDHTYLSSTFTKGERALL 569
            S+S S  N++   G  +    S G    TA     + T +        +++ T  E   +
Sbjct: 1207 STSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTV 1266

Query: 570  SIT-DNSSSSDIVESSTSYI----------KISNSSHSEYSSFFHAQTERSNIS-----S 613
            SIT   ++++    SST+++           I+N+  S   +     T  S+++      
Sbjct: 1267 SITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRPTASSSVTMAPGMD 1326

Query: 614  YDGEYAQPSTESPVLHTSNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSSSSSS--S 671
            +    A  +    VL+TS L   T T+   +T     T A  V  ++ S+   +SS+   
Sbjct: 1327 FTASAASHTVPGIVLNTSGLG--TSTMGASST-----TSAHGVRTTTGSTREPTSSTFQE 1379

Query: 672  SGP-PLPLPSVSQSHHLFSSILPS 694
            +GP  +   +VS SH   + I PS
Sbjct: 1380 TGPVSMGTNTVSMSHTPTNVIKPS 1403



 Score = 61.2 bits (147), Expect = 6e-09
 Identities = 106/542 (19%), Positives = 202/542 (37%), Gaps = 41/542 (7%)

Query: 644  NTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSILPSTRASVHLLK 703
            NT+    T +E  +     +S ++++S++G     PS + S    ++I+  + + +    
Sbjct: 14   NTTTASTTGSE-TTTILIKASETTTASTAGSETTTPSPTGSQ---TTIVSISGSEITTTS 69

Query: 704  STSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQSSSTPVLPRARETPVTSFQTSTM 763
            +    +T  SS+ S      TT++ A    + +T    ++T  +     T V++  + T 
Sbjct: 70   TAGSENTTVSSAGS----GTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETT 125

Query: 764  TSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESS 823
            T+  T   ++ T+   S++T         S++ +  +  +E+T A TT S +    T  S
Sbjct: 126  TNSTTSSETTVTSTAGSETTTVS---TVGSETTTAYTADSETTAASTTGSEMTTVFTAGS 182

Query: 824  TEQTLPATSTNLAQMSPTFTTTILKTSQPLMTTPGTLSSTASLVTGPIAVQTTAGKQLSL 883
             E   P+T+      S T T +   +    ++T G+ ++TAS         +T G + + 
Sbjct: 183  -ETITPSTAG-----SETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTK 236

Query: 884  THPEILVPQISTEGGIST-------ERNRVIV-DATTGLIPLTSVPTSAKEMTTKLGVTA 935
                     +ST G  +T       E N     D+ T     T   T+A   T      A
Sbjct: 237  VSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMA 296

Query: 936  EYSPASRSLGTSPSPQTTVVSTAED-----LAPKSATFAVQSSTQSPTTVSSSASVNSCA 990
                +  ++ ++  P+TT VSTA        A  S T    +     TTVS++ S  + A
Sbjct: 297  STMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTA 356

Query: 991  VNPCLHNGECVADNTSRGYHCRCPPSWQGDDCSVDVNE-----CLSNPCPSTAMCNNTQG 1045
                +   E   D+T+         S +G + +    E      +S     T   + T  
Sbjct: 357  ---SIMGSETSTDSTTGSE--TTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDS 411

Query: 1046 SFICKCPVGYQLEKGICNLVRTFVTEFKLKRTFLNTTVEKHSDLQEVENEITKTLNMCFS 1105
                 C  G ++      +  T     +     + +T +  +     E   T T+    S
Sbjct: 412  ETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGS 471

Query: 1106 ALPSYIRSTVHASRESNAVVISLQTTFSLASNVTLFDLADRMQKCVNSCKSSAEVCQLLG 1165
               +   +    +  SN   +   T F++ S+ T           V++  S        G
Sbjct: 472  ETKTAYTTGSETTTASN-TGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEG 530

Query: 1166 SQ 1167
            S+
Sbjct: 531  SE 532


>gi|239740724 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1704

 Score =  134 bits (336), Expect = 8e-31
 Identities = 217/904 (24%), Positives = 370/904 (40%), Gaps = 98/904 (10%)

Query: 134 STVSSKEGVMVQTSGKSHAASDAPENLTLLAETAD----ARGRSGSSSRTNFTILPVGYS 189
           ++ +S E  +  T+G          + T  A TAD    A   +GS   T FT      +
Sbjct: 127 NSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETIT 186

Query: 190 LEIATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTASEMGTERAMGLSEEWTVH 249
              A + T+      SE+  + ++ SE      A  +++  AS MG+E     ++  T  
Sbjct: 187 PSTAGSETTTVSTAGSETTTVSTTGSETTTASTA-HSETTAASTMGSE----TTKVSTAG 241

Query: 250 SQEATTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASS----PLLDLSSS 305
           S+   ++A S +   + E  E T  +   +S     S   F  TAAS+    P +  +  
Sbjct: 242 SETTVSTAGSETTAASTEDSE-TNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMG 300

Query: 306 SESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVSKTEGFPKDSRI 365
           SE+T  + ++ G +++ VS T +  V TVF   G  T+R+ TV  G  + T      +  
Sbjct: 301 SETT--MASTIGPETTKVS-TASSEVTTVFA-AGSETIRASTV--GSETTT---VSTTGS 351

Query: 366 ATTSSSVLLSPSAVESRRNSR-VTGNPGDEEFIEPSTENEFGLTSLRWQNDSPTFGEHQL 424
            TT++S++ S ++ +S   S   T +    E    STE     T     +++ T      
Sbjct: 352 ETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDS 411

Query: 425 ASSSEVQNGSPMSQTETV--SRSVAPMRGGEITAHWLLTNSTTSADVTGSSASYPEGVNA 482
            +++    GS M+   T     + A   G EIT      + TT+A   GS  +      +
Sbjct: 412 ETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGS 471

Query: 483 SVLTQFSDSTVQSGGSHTALGDR------SYSESSSTSSSESLNSSAPRGER---SIAGI 533
              T ++  +  +  S+T L         S + ++ST  SE+   SA   E    S  G 
Sbjct: 472 ETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGS 531

Query: 534 SYGQVRGTAIEQRTSSDHTDHTYLSSTFTKG-ERALLSITDNSSSSDIVESSTSYIKISN 592
               V  T  E  T S  T     ++T T+G E   +S T   +++D  E S +    ++
Sbjct: 532 ENTTVSTTGSETTTVS--TTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGT--TAAS 587

Query: 593 SSHSEYSSFFHAQTERSNISSYDGEYAQPST---ESPVLHTSNLPSYTPTINMPNTSVVL 649
           ++ SE ++   A +E +  S+ D E    ST   E+    T++  + T +     T+ V 
Sbjct: 588 TAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVS 647

Query: 650 DTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSILPSTRASVHLLKSTSDAS 709
            TD+E    S++ S  + +S+       + +      + +    +T  S+     T   +
Sbjct: 648 TTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSI-----TGSET 702

Query: 710 TPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQSSSTPVLPRARETPVTSFQTSTMTSFMTM 769
           T  S++ S      TT+++    ++  ++  S +T       ET   S + S  TS  T 
Sbjct: 703 TKVSTTGS----ETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTT 758

Query: 770 LHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESST----- 824
              + TA   S  T     + +E+   S +   +E+TK  T +S +    TE+S      
Sbjct: 759 GSETTTASTTSSETTMASIMGSETTMASTIG--SETTKVSTASSKMTTVFTENSETTIAS 816

Query: 825 -------------EQTLPATSTNLAQMSPTFTTTILKTSQ-PLMTTPGTLSSTASLVTGP 870
                         +T+PA++      S T TTT  + S+    +T G+ ++TAS  +  
Sbjct: 817 TTASETTTVSTAGSETIPASTAG----SETTTTTSTEGSETTTASTEGSETTTASTESSE 872

Query: 871 IAVQTTAGKQLSLTHPEILVPQISTEGG----ISTERNRVIVDATTGLIPLTSVPTSAKE 926
               TT G + +           STEG      STE +     +T G   +T+V T+  E
Sbjct: 873 TTTATTIGSETTTA---------STEGSETTTTSTEGSETTTASTEG-SEITTVSTTGSE 922

Query: 927 MTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSATFAVQSSTQSPTTVSSSASV 986
            TT     +E + AS    T  S  TTV +T  +    SA     S T + TT+ S  + 
Sbjct: 923 TTTASTEGSETTTAS----TEGSELTTVSTTGSETITVSAE---GSETTTVTTMGSETTT 975

Query: 987 NSCA 990
            S A
Sbjct: 976 ASTA 979



 Score =  129 bits (323), Expect = 3e-29
 Identities = 202/902 (22%), Positives = 348/902 (38%), Gaps = 76/902 (8%)

Query: 114  ESNTEAHVENITFYQNQEDFSTVSSKEGVMVQTSGKSHAASDAPENLTLLAETADARGRS 173
            +S T +     +   ++   ++    E   V T+G         ++ T    T  +   +
Sbjct: 366  DSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTA 425

Query: 174  GSSSRTNFTILPV-GYSLEIATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTAS 232
             S++    T     G  + IA+   S++   ++E     + ++   E   A+ T S T +
Sbjct: 426  VSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTT 485

Query: 233  EMGTERAMGLSEEWTVHSQEATTSAWSPSFLPALEMG-ELTTPSRKRNSSGPDLSWLHFY 291
               T   +  +  +T+ S   T S            G E+TT S + + +    +     
Sbjct: 486  ASNT--GLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSET 543

Query: 292  RTAASSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLG 351
             T +++ L   ++S+E +E    ST    ++   T+        T G   T    TVS  
Sbjct: 544  TTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETT----TVSTA 599

Query: 352  PVSKTEGFPKDSRIATTSSSVLLSPSAVESRRNSRVT--GNPGDEEFIEPSTENEFGLTS 409
                T     DS   TTS+S   S +   S  +S  T     G E     +T++E  + S
Sbjct: 600  DSENTTASTADSE--TTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVS 657

Query: 410  LRWQNDSPTFGEHQLASSSEVQNGSPMSQT---ETVSRSVAPMRGGEITAHWLLTNSTTS 466
                    T G  +  +S+E    + +S T    TVS   +      IT       STT 
Sbjct: 658  --------TTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTG 709

Query: 467  ADVTGSSASYPEGVNASVLTQFSDSTVQSGGSHTALGDRSYSE--SSSTSSSESLNSSAP 524
            ++ T +S    E   AS+ T    +T  + GS T       SE  S+ST+ SE+  +S  
Sbjct: 710  SETTTTSTEGSEITTASI-TGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTT 768

Query: 525  RGERSIAGISYGQVR-GTAIEQRTSSDHTDHTYLSSTFTKGERALLSITDNSSSSDIVES 583
              E ++A I   +    + I   T+   T  + +++ FT+     ++ T  S ++ +  +
Sbjct: 769  SSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTA 828

Query: 584  STSYIKISNSSHSEYSSFFHAQTERSNISSYDGEYAQPSTESPVLHTSNLPSYTPTINMP 643
             +  I  S +     ++     +E +  S+   E    STES    T+       TI   
Sbjct: 829  GSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTAT------TIGSE 882

Query: 644  NTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSI------LPSTRA 697
             T+    T+    + +S+  S ++++S+ G  +   S + S    +S         ST  
Sbjct: 883  TTTA--STEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEG 940

Query: 698  SVHLLKSTSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQSSSTPVLPRARETPVTS 757
            S     ST+ + T   S+      ++TT  S   + S      S +T V     ET   S
Sbjct: 941  SELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAG---SETTTVSTAGSETTTAS 997

Query: 758  FQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPT---ESTKAVTTNSP 814
             + S  T+      SS  ++  + ST   E  IT ++     ++ T   E+T   TT S 
Sbjct: 998  IEGSETTTV-----SSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSE 1052

Query: 815  LPPSLTESSTEQTLPATSTNLAQMSPT-FTTTILKTSQPLMTTPGTLSSTASLVTGPIAV 873
               + TE S   T+  T +     S     TT + TS    TT  T  S  + V    + 
Sbjct: 1053 TTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSK 1112

Query: 874  QTTAGKQLSLTHPEILVPQISTEGG----ISTERNRVIVDATTGLIPLTSVPTSAKEMTT 929
             TTA                STEG     +ST  +     +TTG   +T+V T+  E TT
Sbjct: 1113 TTTA----------------STEGSEATTVSTTSSETTTASTTG-SEMTTVFTTVSETTT 1155

Query: 930  --KLGVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSATFAVQSSTQSPTTVSSSASVN 987
               +G  A  S A+ S  T+ S + +  +TA     ++ T +   S  +  + S S +  
Sbjct: 1156 VSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNT 1215

Query: 988  SC 989
            +C
Sbjct: 1216 AC 1217



 Score =  118 bits (296), Expect = 3e-26
 Identities = 200/902 (22%), Positives = 348/902 (38%), Gaps = 74/902 (8%)

Query: 134  STVSSKEGVMVQTSG-KSHAASDAPENLTLLAETADARGRSGSSSRTNFTILPVGYSLEI 192
            ST+ S E  M  T G ++   S A   +T +        R+ +      T+   G     
Sbjct: 297  STMGS-ETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTT 355

Query: 193  ATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTASEMGTERAMGLSEEWTVH--S 250
            A+ + S++   ++      ++S+E  E   A    S   SE  T    G SE  TV    
Sbjct: 356  ASIMGSETSTDSTTGSETTTASTEGSETTTA----STEGSEATTVSTTG-SETTTVSITD 410

Query: 251  QEATTSAWSPSFLPAL------------EMGELT---TPSRKRNSSGPDLSWLHFYRTAA 295
             E TT+    S + A+            E  E+T   T   +  ++  + S      TA 
Sbjct: 411  SETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAG 470

Query: 296  SSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVSK 355
            S      ++ SE+T   N  TGL++++V  T      T  T+G   T  S T S      
Sbjct: 471  SETKTAYTTGSETTTASN--TGLETTTVF-TIGSDTTTASTEGSETTAVSATGSEMTTVS 527

Query: 356  TEGFPKDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQND 415
            TEG    +   T S +  +S + +E+   S         E  E +T +  G  +     +
Sbjct: 528  TEGSENTTVSTTGSETTTVSTTGLETTTTST--------EGSEMTTVSTTGAETTTDSTE 579

Query: 416  SPTFGEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADVTGSSAS 475
                     A S      +  S+  T S + +       T     T STTS++ T +S  
Sbjct: 580  GSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTE 639

Query: 476  YPEGVNASVLTQFSDSTVQSGGSHTALGDRSYSESSSTSSSESLNSSAPRGER----SIA 531
              E    S  T    + V + GS   +     SE+++ S++ S  + +  G      SI 
Sbjct: 640  GSETTTVST-TDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSIT 698

Query: 532  GISYGQVRGTAIEQRTSSDHTDHTYLSS--------TFTKGERALLSITDNS--SSSDIV 581
            G    +V  T  E  T+S        +S          T+G     + T+ S  +S+   
Sbjct: 699  GSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTT 758

Query: 582  ESSTSYIKISNSSHSEYSSFFHAQTERSNISSYDGEYAQPSTESPVLHTSNLPSYTPTIN 641
             S T+    ++S  +  S      T  S I S   + +  S++   + T N  +   +  
Sbjct: 759  GSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTT 818

Query: 642  MPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSILPS-TRASVH 700
               T+ V    +E +  S++ S +++++S+ G      S   S    +S   S T  +  
Sbjct: 819  ASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATT 878

Query: 701  LLKSTSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQ--SSSTPVLPRARETPVTSF 758
            +   T+ AST  S + +       T+T++      TT+    S +T       ET   S 
Sbjct: 879  IGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAST 938

Query: 759  QTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPS 818
            + S +T+  T    S+T  + ++ +         S++ +  +  +E+T   T  S    +
Sbjct: 939  EGSELTTVSTT--GSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTA 996

Query: 819  LTESSTEQTLPATSTNLAQMSPTFTTTILKTSQPLMTTPGTLSSTASLVTGPIAVQTTAG 878
              E S   T+ +T +    +S T T T + +++   TT  T+++  S  T   AV TT  
Sbjct: 997  SIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETT--TVTTAGSETT---AVYTTGS 1051

Query: 879  KQLSLTHPEILVPQISTEGGISTERNRVIVDATTGLIP---LTSVPTSAKEMTTKLGVTA 935
            +  + +        +ST G  +T  +   ++ TT        T+  T+  E TT     +
Sbjct: 1052 ETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGS 1111

Query: 936  EYSPASRSLGTSPSPQTTVVSTAEDLAPKSAT-------FAVQSSTQSPTTVSSSASVNS 988
            + + AS    T  S  TTV +T+ +    S T       F   S T + +T+ S A+ +S
Sbjct: 1112 KTTTAS----TEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSS 1167

Query: 989  CA 990
             A
Sbjct: 1168 AA 1169



 Score =  111 bits (278), Expect = 4e-24
 Identities = 201/949 (21%), Positives = 373/949 (39%), Gaps = 110/949 (11%)

Query: 124  ITFYQNQEDFSTVSSKEGVMVQTSGKSHAASDAPENLTLLAETADARGRSGSSSRTNFTI 183
            IT     +  +T +S EG   +T+  + A S+     T  +ET  A   +G  + T FTI
Sbjct: 443  ITIASTSDSETTTASTEGS--ETTTVTTAGSETKTAYTTGSETTTA-SNTGLETTTVFTI 499

Query: 184  LPVGYSLEIATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTASEMGTERAMGLS 243
               G     A+   S++  +++    + + S+E  E      T S T SE  T    GL 
Sbjct: 500  ---GSDTTTASTEGSETTAVSATGSEMTTVSTEGSENT----TVSTTGSETTTVSTTGLE 552

Query: 244  EEWTVH--SQEATTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASSPLLD 301
               T    S+  T S            G  TT +    S    +S      T AS+   +
Sbjct: 553  TTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSE 612

Query: 302  LSSSSES-TEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVSKTEGFP 360
             +S+S + +E    ST    ++ + T+     TV T     T+ S T S   ++ TEG  
Sbjct: 613  TTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSE 672

Query: 361  ----------------------------KDSRIATTSSSVLLSPSAVESRRNSRVTGNPG 392
                                        + ++++TT S    + +       + +TG+  
Sbjct: 673  TTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSET 732

Query: 393  DEEFIEPSTENEFGLTSLRWQNDSPTFGEHQLAS--SSEVQNGSPMSQTETVSRSVAPMR 450
                 E S             + S T  E   AS  SSE    S M    T++ ++    
Sbjct: 733  TTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSET 792

Query: 451  GGEITAHWLLTN-----------STTSADVTGSSASYPEGVNASVLTQFSDSTVQSGGSH 499
                TA   +T            STT+++ T  S +  E + AS     + +T  + GS 
Sbjct: 793  TKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSE 852

Query: 500  TALGDRSYSESS--STSSSESLNSSAPRGERSIAGISYGQVRGTAIE-QRTSSDHTDHTY 556
            T       SE++  ST SSE+  ++    E + A     +   T+ E   T++  T+ + 
Sbjct: 853  TTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSE 912

Query: 557  LSSTFTKGERALLSITDNSSSSDIVESSTSYIKISNSSHSEYSSFFHAQTERSNISSYDG 616
            +++  T G     + T+ S ++      +    +S +  SE  +     +E + +++   
Sbjct: 913  ITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTG-SETITVSAEGSETTTVTTMGS 971

Query: 617  EYAQPST---ESPVLHTSNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSG 673
            E    ST   E+  + T+   + T +I    T+ V  T +E  + S++ + ++ +S+   
Sbjct: 972  ETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGS 1031

Query: 674  PPLPLPSV-SQSHHLFSS----ILPSTRASVHLLKSTSDASTPWSSSPSPLPVSLTTS-- 726
                + +  S++  ++++       ST  S     ST+ + T  +S+      +++TS  
Sbjct: 1032 ETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGS 1091

Query: 727  --TSAPLSVSQTTLPQ-------------SSSTPVLPRARETPVTSFQTSTMTSFMTMLH 771
              T+A  + S+TT                S +T V   + ET   S   S MT+  T + 
Sbjct: 1092 GTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVS 1151

Query: 772  SSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESSTEQTLPAT 831
             + T      ST   E   + +      +  TE ++  TT S      T +ST  +   T
Sbjct: 1152 ETTTV-----STIGSEATTSSAAGSEATTTSTEGSE-TTTASTAGSETTTASTAGSETTT 1205

Query: 832  STNLAQMSPTFTTTILKTSQPLMTTPGTLSSTASLVTGPIAVQTTAGKQ---LSLTHPEI 888
            ++     + T  TT  +TS P  ++ G+ ++TA ++     + +TA  +    SLT  E 
Sbjct: 1206 ASTSGSETNTACTTGSETSTP--SSAGSETNTAFIIGSETTIASTASLEPTATSLTGSET 1263

Query: 889  LVPQISTEGGISTERNRVIVDATTGLIPLTSVPTSAKEMTTKLGVTAEYSPASRSLGTSP 948
                I+  G  +         A+T +   T V T A +++ +  +T      +R+ GT P
Sbjct: 1264 TTVSITASGATA---------ASTTVSSTTFVLTKATDVSIQ-PITNTPMSGTRTTGTRP 1313

Query: 949  SPQTTV-VSTAEDLAPKSATFAV-----QSSTQSPTTVSSSASVNSCAV 991
            +  ++V ++   D    +A+  V      +S    +T+ +S++ ++  V
Sbjct: 1314 TASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGV 1362



 Score =  105 bits (261), Expect = 4e-22
 Identities = 191/857 (22%), Positives = 342/857 (39%), Gaps = 147/857 (17%)

Query: 230 TASEMGTERAMGLSEEWTVHSQEATTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLH 289
           TAS  G+E    L     + + E TT++ + S        E TTPS       P  S   
Sbjct: 17  TASTTGSETTTIL-----IKASETTTASTAGS--------ETTTPS-------PTGSQTT 56

Query: 290 FYRTAASSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVS 349
               + S      ++ SE+T   +  +G  ++S++ ++T    TV T G   T  S+T +
Sbjct: 57  IVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSET----TVSTAGSETTTVSITGT 112

Query: 350 LGPVSKTEGFPKDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTS 409
              +    G    +   T+S + + S +  E+   S V    G E     + ++E    S
Sbjct: 113 ETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTV----GSETTTAYTADSETTAAS 168

Query: 410 LRWQNDSPTFGEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADV 469
                 +  F     A S  +   +  S+T TVS +     G E T     T STT ++ 
Sbjct: 169 TTGSEMTTVF----TAGSETITPSTAGSETTTVSTA-----GSETT-----TVSTTGSET 214

Query: 470 TGSSASYPEGVNAS--------VLTQFSDSTVQSGGS------------HTALGDRSYSE 509
           T +S ++ E   AS        V T  S++TV + GS            +TA  + S + 
Sbjct: 215 TTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTT 274

Query: 510 SSSTSSSESLNSSAPRGERSIAGISYGQ-VRGTAIEQRTSSDHTDHTYLSSTFTKGERAL 568
           ++ST+  E+  +S    E ++A     +    + I   T+   T  + +++ F  G   +
Sbjct: 275 TASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETI 334

Query: 569 LSITDNSSSSDIVESSTSYIKISNSSHSEYSSFFHAQTERSNISSYDGEYAQPSTE-SPV 627
            + T  S ++  V ++ S    ++   SE S+     +E +  S+   E    STE S  
Sbjct: 335 RASTVGSETT-TVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEA 393

Query: 628 LHTSNLPSYTPTINMPNT---------------------SVVLDTDAEFVSDSSSSSSSS 666
              S   S T T+++ ++                     +    T+   ++ +S+S S +
Sbjct: 394 TTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSET 453

Query: 667 SSSSSSGPPLPLPSV--SQSHHLFSSILPSTRASVHLLKST------SDASTPWSSSPSP 718
           +++S+ G      +   S++   +++   +T AS   L++T      SD +T  +     
Sbjct: 454 TTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSET 513

Query: 719 LPVSLTTSTSAPLSV---SQTTLPQ--SSSTPVLPRARETPVTSFQTSTMTSFMT----- 768
             VS T S    +S      TT+    S +T V     ET  TS + S MT+  T     
Sbjct: 514 TAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAET 573

Query: 769 -------------MLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPL 815
                            S+T  + +  + +      +S++ S  +  +E+T A TT+S  
Sbjct: 574 TTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSET 633

Query: 816 PPSLTESSTEQTLPATSTNLAQMSPT------------FTTTILKT-SQPLMTTPGTLSS 862
             + TE S   T+  T +    +S T             TTT+  T S+  ++T G+ ++
Sbjct: 634 TTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTT 693

Query: 863 TASLVTGPIAVQTTAGKQLSLTH---PEILVPQI--------STEGG----ISTERNRVI 907
           T S+        +T G + + T     EI    I        STEG      STE +   
Sbjct: 694 TVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETT 753

Query: 908 VDATTGLIPLTSVPTSAKEMTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSAT 967
             +TTG    T+  TS++  TT   +    +  + ++G+  +  +T  S    +  +++ 
Sbjct: 754 SASTTGSETTTASTTSSE--TTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSE 811

Query: 968 FAVQSSTQSPTTVSSSA 984
             + S+T S TT  S+A
Sbjct: 812 TTIASTTASETTTVSTA 828



 Score = 93.6 bits (231), Expect = 1e-18
 Identities = 138/603 (22%), Positives = 237/603 (39%), Gaps = 69/603 (11%)

Query: 445 SVAPMRGGEITAHWLLTNSTTSADVTGSSASYPE---------GVNASVLTQFS-----D 490
           + A   G E T   +  + TT+A   GS  + P           ++ S +T  S     +
Sbjct: 16  TTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSEN 75

Query: 491 STVQSGGSHTALGDRSYSESS-STSSSESLNSSAPRGERSIAGISYGQVRGTAIEQRTSS 549
           +TV S GS T     + SE++ ST+ SE+          SI G     V     E  T+S
Sbjct: 76  TTVSSAGSGTTTASMAGSETTVSTAGSETTTV-------SITGTETTMVSAMGSETTTNS 128

Query: 550 DHTDHTYLSSTFTKGERALLSITDNSSSSDIVESSTSYIKISNSSHSEYSSFFHAQTERS 609
             +  T ++ST       + ++   ++++   +S T+    ++++ SE ++ F A +E  
Sbjct: 129 TTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETT---AASTTGSEMTTVFTAGSETI 185

Query: 610 NISSYDGEYAQPST---ESPVLHTSNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSS 666
             S+   E    ST   E+  + T+   + T +     T+      +E    S++ S ++
Sbjct: 186 TPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETT 245

Query: 667 SSSSSSGPPLPLPSVSQSHHLFSSILPSTRASVHLLKSTSDASTPWSSSPSPLPVSLTTS 726
            S++ S         S+++  F+    +T AS    ++T+ AST  S       +   T+
Sbjct: 246 VSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTA-ASTTGSEPTMASTMGSETT 304

Query: 727 TSAPLSVSQTTLPQSSS--TPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADL-----K 779
            ++ +    T +  +SS  T V     ET   S   S  T+  T    + TA +      
Sbjct: 305 MASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETS 364

Query: 780 SQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESSTEQTLPATSTNLAQMS 839
           + ST   E     ++     +  TE ++A T ++    + T S T+     T T  ++M+
Sbjct: 365 TDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMT 424

Query: 840 PTFTT--------------TILKTSQPLMTTPGTLSSTASLVT----GPIAVQTTAGKQL 881
              TT              TI  TS    TT  T  S  + VT          TT  +  
Sbjct: 425 AVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETT 484

Query: 882 SLTHPEILVPQISTEGG----ISTERNRVIVDATTGLIPLTSVPTSAKEMTTKLGVTAEY 937
           + ++  +    + T G      STE +     + TG   +T+V T   E TT     +E 
Sbjct: 485 TASNTGLETTTVFTIGSDTTTASTEGSETTAVSATG-SEMTTVSTEGSENTTVSTTGSET 543

Query: 938 SPAS------RSLGTSPSPQTTV----VSTAEDLAPKSATFAVQSSTQSPTTVSSSASVN 987
           +  S       +  T  S  TTV      T  D    S T A  ++    TTVS++ S N
Sbjct: 544 TTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSEN 603

Query: 988 SCA 990
           + A
Sbjct: 604 TTA 606



 Score = 75.5 bits (184), Expect = 3e-13
 Identities = 146/624 (23%), Positives = 255/624 (40%), Gaps = 74/624 (11%)

Query: 116  NTEAHVENITFYQNQEDFSTVSS--KEGVMVQTSGK---SHAASDAPENLTLLAETADAR 170
            N+E  + + T      + +TVS+   E +   T+G    +  +++  E  T   E ++  
Sbjct: 809  NSETTIASTT----ASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETT 864

Query: 171  GRSGSSSRTNFTILPVGYSLEIATALTSQSGNLASESLHLPSSSSEFDE--RIAAFQTKS 228
              S  SS T  T   +G     A+   S++   ++E     ++S+E  E   ++   +++
Sbjct: 865  TASTESSETT-TATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSET 923

Query: 229  GTASEMGTERAMGLSEEW------TVHSQEATTSAWSPSFLPALEMGELTTPSRKRNSSG 282
             TAS  G+E     +E        T  S+  T SA          MG  TT +    S  
Sbjct: 924  TTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSET 983

Query: 283  PDLSWLHFYRTAASSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRT 342
              +S      TA S         SE+T    +STG ++++VS T T    T  T+G   T
Sbjct: 984  TTVS------TAGSETTTASIEGSETTTV--SSTGSETTTVSTTGTETTITS-TEGSETT 1034

Query: 343  LRSLTVSLGPVSKTEGFPKDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTE 402
                TV+      T  +   S   TTS+      + V +  +   T +  D E    ST 
Sbjct: 1035 ----TVTTAGSETTAVYTTGSETTTTSTEGS-ETTTVSTTGSETTTASTADLETTTVSTS 1089

Query: 403  NEFGLTSLRWQNDSPTF---GEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWL 459
                 T+    +++ T    G     +S+E    + +S T + + + A   G E+T  + 
Sbjct: 1090 GSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSET-TTASTTGSEMTTVFT 1148

Query: 460  LTNSTTS-----ADVTGSSASYPEGVNASVLTQFSDSTVQS-GGSHTALGDRSYSESSST 513
              + TT+     ++ T SSA+  E    S  T+ S++T  S  GS T     + SE+++ 
Sbjct: 1149 TVSETTTVSTIGSEATTSSAAGSEATTTS--TEGSETTTASTAGSETTTASTAGSETTTA 1206

Query: 514  SSSES-LNSSAPRGERSIAGISYGQVRGTAI---EQRTSSDHTDHTYLSSTFTKGERALL 569
            S+S S  N++   G  +    S G    TA     + T +        +++ T  E   +
Sbjct: 1207 STSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTV 1266

Query: 570  SIT-DNSSSSDIVESSTSYI----------KISNSSHSEYSSFFHAQTERSNIS-----S 613
            SIT   ++++    SST+++           I+N+  S   +     T  S+++      
Sbjct: 1267 SITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRPTASSSVTMAPGMD 1326

Query: 614  YDGEYAQPSTESPVLHTSNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSSSSSS--S 671
            +    A  +    VL+TS L   T T+   +T     T A  V  ++ S+   +SS+   
Sbjct: 1327 FTASAASHTVPGIVLNTSGLG--TSTMGASST-----TSAHGVRTTTGSTREPTSSTFQE 1379

Query: 672  SGP-PLPLPSVSQSHHLFSSILPS 694
            +GP  +   +VS SH   + I PS
Sbjct: 1380 TGPVSMGTNTVSMSHTPTNVIKPS 1403



 Score = 61.2 bits (147), Expect = 6e-09
 Identities = 106/542 (19%), Positives = 202/542 (37%), Gaps = 41/542 (7%)

Query: 644  NTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSILPSTRASVHLLK 703
            NT+    T +E  +     +S ++++S++G     PS + S    ++I+  + + +    
Sbjct: 14   NTTTASTTGSE-TTTILIKASETTTASTAGSETTTPSPTGSQ---TTIVSISGSEITTTS 69

Query: 704  STSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQSSSTPVLPRARETPVTSFQTSTM 763
            +    +T  SS+ S      TT++ A    + +T    ++T  +     T V++  + T 
Sbjct: 70   TAGSENTTVSSAGS----GTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETT 125

Query: 764  TSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESS 823
            T+  T   ++ T+   S++T         S++ +  +  +E+T A TT S +    T  S
Sbjct: 126  TNSTTSSETTVTSTAGSETTTVS---TVGSETTTAYTADSETTAASTTGSEMTTVFTAGS 182

Query: 824  TEQTLPATSTNLAQMSPTFTTTILKTSQPLMTTPGTLSSTASLVTGPIAVQTTAGKQLSL 883
             E   P+T+      S T T +   +    ++T G+ ++TAS         +T G + + 
Sbjct: 183  -ETITPSTAG-----SETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTK 236

Query: 884  THPEILVPQISTEGGIST-------ERNRVIV-DATTGLIPLTSVPTSAKEMTTKLGVTA 935
                     +ST G  +T       E N     D+ T     T   T+A   T      A
Sbjct: 237  VSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMA 296

Query: 936  EYSPASRSLGTSPSPQTTVVSTAED-----LAPKSATFAVQSSTQSPTTVSSSASVNSCA 990
                +  ++ ++  P+TT VSTA        A  S T    +     TTVS++ S  + A
Sbjct: 297  STMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTA 356

Query: 991  VNPCLHNGECVADNTSRGYHCRCPPSWQGDDCSVDVNE-----CLSNPCPSTAMCNNTQG 1045
                +   E   D+T+         S +G + +    E      +S     T   + T  
Sbjct: 357  ---SIMGSETSTDSTTGSE--TTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDS 411

Query: 1046 SFICKCPVGYQLEKGICNLVRTFVTEFKLKRTFLNTTVEKHSDLQEVENEITKTLNMCFS 1105
                 C  G ++      +  T     +     + +T +  +     E   T T+    S
Sbjct: 412  ETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGS 471

Query: 1106 ALPSYIRSTVHASRESNAVVISLQTTFSLASNVTLFDLADRMQKCVNSCKSSAEVCQLLG 1165
               +   +    +  SN   +   T F++ S+ T           V++  S        G
Sbjct: 472  ETKTAYTTGSETTTASN-TGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEG 530

Query: 1166 SQ 1167
            S+
Sbjct: 531  SE 532


>gi|239740674 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score =  134 bits (336), Expect = 8e-31
 Identities = 217/904 (24%), Positives = 370/904 (40%), Gaps = 98/904 (10%)

Query: 134 STVSSKEGVMVQTSGKSHAASDAPENLTLLAETAD----ARGRSGSSSRTNFTILPVGYS 189
           ++ +S E  +  T+G          + T  A TAD    A   +GS   T FT      +
Sbjct: 127 NSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETIT 186

Query: 190 LEIATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTASEMGTERAMGLSEEWTVH 249
              A + T+      SE+  + ++ SE      A  +++  AS MG+E     ++  T  
Sbjct: 187 PSTAGSETTTVSTAGSETTTVSTTGSETTTASTA-HSETTAASTMGSE----TTKVSTAG 241

Query: 250 SQEATTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASS----PLLDLSSS 305
           S+   ++A S +   + E  E T  +   +S     S   F  TAAS+    P +  +  
Sbjct: 242 SETTVSTAGSETTAASTEDSE-TNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMG 300

Query: 306 SESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVSKTEGFPKDSRI 365
           SE+T  + ++ G +++ VS T +  V TVF   G  T+R+ TV  G  + T      +  
Sbjct: 301 SETT--MASTIGPETTKVS-TASSEVTTVFA-AGSETIRASTV--GSETTT---VSTTGS 351

Query: 366 ATTSSSVLLSPSAVESRRNSR-VTGNPGDEEFIEPSTENEFGLTSLRWQNDSPTFGEHQL 424
            TT++S++ S ++ +S   S   T +    E    STE     T     +++ T      
Sbjct: 352 ETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDS 411

Query: 425 ASSSEVQNGSPMSQTETV--SRSVAPMRGGEITAHWLLTNSTTSADVTGSSASYPEGVNA 482
            +++    GS M+   T     + A   G EIT      + TT+A   GS  +      +
Sbjct: 412 ETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGS 471

Query: 483 SVLTQFSDSTVQSGGSHTALGDR------SYSESSSTSSSESLNSSAPRGER---SIAGI 533
              T ++  +  +  S+T L         S + ++ST  SE+   SA   E    S  G 
Sbjct: 472 ETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGS 531

Query: 534 SYGQVRGTAIEQRTSSDHTDHTYLSSTFTKG-ERALLSITDNSSSSDIVESSTSYIKISN 592
               V  T  E  T S  T     ++T T+G E   +S T   +++D  E S +    ++
Sbjct: 532 ENTTVSTTGSETTTVS--TTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGT--TAAS 587

Query: 593 SSHSEYSSFFHAQTERSNISSYDGEYAQPST---ESPVLHTSNLPSYTPTINMPNTSVVL 649
           ++ SE ++   A +E +  S+ D E    ST   E+    T++  + T +     T+ V 
Sbjct: 588 TAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVS 647

Query: 650 DTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSILPSTRASVHLLKSTSDAS 709
            TD+E    S++ S  + +S+       + +      + +    +T  S+     T   +
Sbjct: 648 TTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSI-----TGSET 702

Query: 710 TPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQSSSTPVLPRARETPVTSFQTSTMTSFMTM 769
           T  S++ S      TT+++    ++  ++  S +T       ET   S + S  TS  T 
Sbjct: 703 TKVSTTGS----ETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTT 758

Query: 770 LHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESST----- 824
              + TA   S  T     + +E+   S +   +E+TK  T +S +    TE+S      
Sbjct: 759 GSETTTASTTSSETTMASIMGSETTMASTIG--SETTKVSTASSKMTTVFTENSETTIAS 816

Query: 825 -------------EQTLPATSTNLAQMSPTFTTTILKTSQ-PLMTTPGTLSSTASLVTGP 870
                         +T+PA++      S T TTT  + S+    +T G+ ++TAS  +  
Sbjct: 817 TTASETTTVSTAGSETIPASTAG----SETTTTTSTEGSETTTASTEGSETTTASTESSE 872

Query: 871 IAVQTTAGKQLSLTHPEILVPQISTEGG----ISTERNRVIVDATTGLIPLTSVPTSAKE 926
               TT G + +           STEG      STE +     +T G   +T+V T+  E
Sbjct: 873 TTTATTIGSETTTA---------STEGSETTTTSTEGSETTTASTEG-SEITTVSTTGSE 922

Query: 927 MTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSATFAVQSSTQSPTTVSSSASV 986
            TT     +E + AS    T  S  TTV +T  +    SA     S T + TT+ S  + 
Sbjct: 923 TTTASTEGSETTTAS----TEGSELTTVSTTGSETITVSAE---GSETTTVTTMGSETTT 975

Query: 987 NSCA 990
            S A
Sbjct: 976 ASTA 979



 Score =  128 bits (321), Expect = 4e-29
 Identities = 209/911 (22%), Positives = 353/911 (38%), Gaps = 84/911 (9%)

Query: 114  ESNTEAHVENITFYQNQEDFSTVSSKEGVMVQTSGKSHAASDAPENLTLLAETADARGRS 173
            +S T +     +   ++   ++    E   V T+G         ++ T    T  +   +
Sbjct: 366  DSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTA 425

Query: 174  GSSSRTNFTILPV-GYSLEIATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTAS 232
             S++    T     G  + IA+   S++   ++E     + ++   E   A+ T S T +
Sbjct: 426  VSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTT 485

Query: 233  EMGTERAMGLSEEWTVHSQEATTSAWSPSFLPALEMG-ELTTPSRKRNSSGPDLSWLHFY 291
               T   +  +  +T+ S   T S            G E+TT S + + +    +     
Sbjct: 486  ASNT--GLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSET 543

Query: 292  RTAASSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLG 351
             T +++ L   ++S+E +E    ST    ++   T+        T G   T    TVS  
Sbjct: 544  TTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETT----TVSTA 599

Query: 352  PVSKTEGFPKDSRIATTSSSVLLSPSAVESRRNSRVT--GNPGDEEFIEPSTENEFGLTS 409
                T     DS   TTS+S   S +   S  +S  T     G E     +T++E  + S
Sbjct: 600  DSENTTASTADSE--TTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVS 657

Query: 410  LRWQNDSPTFGEHQLASSSEVQNGSPMSQT---ETVSRSVAPMRGGEITAHWLLTNSTTS 466
                    T G  +  +S+E    + +S T    TVS   +      IT       STT 
Sbjct: 658  --------TTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTG 709

Query: 467  ADVTGSSASYPEGVNASVLTQFSDSTVQSGGSHTALGDRSYSE--SSSTSSSESLNSSAP 524
            ++ T +S    E   AS+ T    +T  + GS T       SE  S+ST+ SE+  +S  
Sbjct: 710  SETTTTSTEGSEITTASI-TGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTT 768

Query: 525  RGERSIAGISYGQVR-GTAIEQRTSSDHTDHTYLSSTFTKGERALLSITDNSSSSDIVES 583
              E ++A I   +    + I   T+   T  + +++ FT+     ++ T  S ++ +  +
Sbjct: 769  SSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTA 828

Query: 584  STSYIKISNSSHSEYSSFFHAQTERSNISSYDGEYAQPSTESPVLHTSNLPSYTPTINMP 643
             +  I  S +     ++     +E +  S+   E    STES    T+       TI   
Sbjct: 829  GSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTAT------TIGSE 882

Query: 644  NTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSI------LPSTRA 697
             T+    T+    + +S+  S ++++S+ G  +   S + S    +S         ST  
Sbjct: 883  TTTA--STEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEG 940

Query: 698  SVHLLKSTSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQSSSTPVLPRARETPVTS 757
            S     ST+ + T   S+      ++TT  S   + S      S +T V     ET   S
Sbjct: 941  SELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAG---SETTTVSTAGSETTTAS 997

Query: 758  FQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPT---ESTKAVTTNSP 814
             + S  T+      SS  ++  + ST   E  IT ++     ++ T   E+T   TT S 
Sbjct: 998  IEGSETTTV-----SSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSE 1052

Query: 815  LPPSLTESSTEQTLPATSTNLAQMSPT-FTTTILKTSQPLMTTPGTLSSTASLVTGPIAV 873
               + TE S   T+  T +     S     TT + TS    TT  T  S  + V    + 
Sbjct: 1053 TTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSK 1112

Query: 874  QTTAGKQLSLTHPEILVPQISTEGG----ISTERNRVIVDATTGLIPLTSVPTSAKEMTT 929
             TTA                STEG     +ST  +     +TTG   +T+V T+  E TT
Sbjct: 1113 TTTA----------------STEGSEATTVSTTSSETTTASTTG-SEMTTVFTTVSETTT 1155

Query: 930  --KLGVTAEYSPASRSLGTSPS---PQTTVVSTAEDLAPKSATFAVQSSTQS-----PTT 979
               +G  A  S A+ S  T+ S    +TT  STA      ++T   +++T S      TT
Sbjct: 1156 VSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTAGSETTT 1215

Query: 980  VSSSASVNSCA 990
             S+S S  + A
Sbjct: 1216 ASTSGSETNTA 1226



 Score =  118 bits (296), Expect = 3e-26
 Identities = 200/902 (22%), Positives = 348/902 (38%), Gaps = 74/902 (8%)

Query: 134  STVSSKEGVMVQTSG-KSHAASDAPENLTLLAETADARGRSGSSSRTNFTILPVGYSLEI 192
            ST+ S E  M  T G ++   S A   +T +        R+ +      T+   G     
Sbjct: 297  STMGS-ETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTT 355

Query: 193  ATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTASEMGTERAMGLSEEWTVH--S 250
            A+ + S++   ++      ++S+E  E   A    S   SE  T    G SE  TV    
Sbjct: 356  ASIMGSETSTDSTTGSETTTASTEGSETTTA----STEGSEATTVSTTG-SETTTVSITD 410

Query: 251  QEATTSAWSPSFLPAL------------EMGELT---TPSRKRNSSGPDLSWLHFYRTAA 295
             E TT+    S + A+            E  E+T   T   +  ++  + S      TA 
Sbjct: 411  SETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAG 470

Query: 296  SSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVSK 355
            S      ++ SE+T   N  TGL++++V  T      T  T+G   T  S T S      
Sbjct: 471  SETKTAYTTGSETTTASN--TGLETTTVF-TIGSDTTTASTEGSETTAVSATGSEMTTVS 527

Query: 356  TEGFPKDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQND 415
            TEG    +   T S +  +S + +E+   S         E  E +T +  G  +     +
Sbjct: 528  TEGSENTTVSTTGSETTTVSTTGLETTTTST--------EGSEMTTVSTTGAETTTDSTE 579

Query: 416  SPTFGEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADVTGSSAS 475
                     A S      +  S+  T S + +       T     T STTS++ T +S  
Sbjct: 580  GSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTE 639

Query: 476  YPEGVNASVLTQFSDSTVQSGGSHTALGDRSYSESSSTSSSESLNSSAPRGER----SIA 531
              E    S  T    + V + GS   +     SE+++ S++ S  + +  G      SI 
Sbjct: 640  GSETTTVST-TDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSIT 698

Query: 532  GISYGQVRGTAIEQRTSSDHTDHTYLSS--------TFTKGERALLSITDNS--SSSDIV 581
            G    +V  T  E  T+S        +S          T+G     + T+ S  +S+   
Sbjct: 699  GSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTT 758

Query: 582  ESSTSYIKISNSSHSEYSSFFHAQTERSNISSYDGEYAQPSTESPVLHTSNLPSYTPTIN 641
             S T+    ++S  +  S      T  S I S   + +  S++   + T N  +   +  
Sbjct: 759  GSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTT 818

Query: 642  MPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSILPS-TRASVH 700
               T+ V    +E +  S++ S +++++S+ G      S   S    +S   S T  +  
Sbjct: 819  ASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATT 878

Query: 701  LLKSTSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQ--SSSTPVLPRARETPVTSF 758
            +   T+ AST  S + +       T+T++      TT+    S +T       ET   S 
Sbjct: 879  IGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAST 938

Query: 759  QTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPS 818
            + S +T+  T    S+T  + ++ +         S++ +  +  +E+T   T  S    +
Sbjct: 939  EGSELTTVSTT--GSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTA 996

Query: 819  LTESSTEQTLPATSTNLAQMSPTFTTTILKTSQPLMTTPGTLSSTASLVTGPIAVQTTAG 878
              E S   T+ +T +    +S T T T + +++   TT  T+++  S  T   AV TT  
Sbjct: 997  SIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETT--TVTTAGSETT---AVYTTGS 1051

Query: 879  KQLSLTHPEILVPQISTEGGISTERNRVIVDATTGLIP---LTSVPTSAKEMTTKLGVTA 935
            +  + +        +ST G  +T  +   ++ TT        T+  T+  E TT     +
Sbjct: 1052 ETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGS 1111

Query: 936  EYSPASRSLGTSPSPQTTVVSTAEDLAPKSAT-------FAVQSSTQSPTTVSSSASVNS 988
            + + AS    T  S  TTV +T+ +    S T       F   S T + +T+ S A+ +S
Sbjct: 1112 KTTTAS----TEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSS 1167

Query: 989  CA 990
             A
Sbjct: 1168 AA 1169



 Score =  105 bits (261), Expect = 4e-22
 Identities = 191/857 (22%), Positives = 342/857 (39%), Gaps = 147/857 (17%)

Query: 230 TASEMGTERAMGLSEEWTVHSQEATTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLH 289
           TAS  G+E    L     + + E TT++ + S        E TTPS       P  S   
Sbjct: 17  TASTTGSETTTIL-----IKASETTTASTAGS--------ETTTPS-------PTGSQTT 56

Query: 290 FYRTAASSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVS 349
               + S      ++ SE+T   +  +G  ++S++ ++T    TV T G   T  S+T +
Sbjct: 57  IVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSET----TVSTAGSETTTVSITGT 112

Query: 350 LGPVSKTEGFPKDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTS 409
              +    G    +   T+S + + S +  E+   S V    G E     + ++E    S
Sbjct: 113 ETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTV----GSETTTAYTADSETTAAS 168

Query: 410 LRWQNDSPTFGEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADV 469
                 +  F     A S  +   +  S+T TVS +     G E T     T STT ++ 
Sbjct: 169 TTGSEMTTVF----TAGSETITPSTAGSETTTVSTA-----GSETT-----TVSTTGSET 214

Query: 470 TGSSASYPEGVNAS--------VLTQFSDSTVQSGGS------------HTALGDRSYSE 509
           T +S ++ E   AS        V T  S++TV + GS            +TA  + S + 
Sbjct: 215 TTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTT 274

Query: 510 SSSTSSSESLNSSAPRGERSIAGISYGQ-VRGTAIEQRTSSDHTDHTYLSSTFTKGERAL 568
           ++ST+  E+  +S    E ++A     +    + I   T+   T  + +++ F  G   +
Sbjct: 275 TASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETI 334

Query: 569 LSITDNSSSSDIVESSTSYIKISNSSHSEYSSFFHAQTERSNISSYDGEYAQPSTE-SPV 627
            + T  S ++  V ++ S    ++   SE S+     +E +  S+   E    STE S  
Sbjct: 335 RASTVGSETT-TVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEA 393

Query: 628 LHTSNLPSYTPTINMPNT---------------------SVVLDTDAEFVSDSSSSSSSS 666
              S   S T T+++ ++                     +    T+   ++ +S+S S +
Sbjct: 394 TTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSET 453

Query: 667 SSSSSSGPPLPLPSV--SQSHHLFSSILPSTRASVHLLKST------SDASTPWSSSPSP 718
           +++S+ G      +   S++   +++   +T AS   L++T      SD +T  +     
Sbjct: 454 TTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSET 513

Query: 719 LPVSLTTSTSAPLSV---SQTTLPQ--SSSTPVLPRARETPVTSFQTSTMTSFMT----- 768
             VS T S    +S      TT+    S +T V     ET  TS + S MT+  T     
Sbjct: 514 TAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAET 573

Query: 769 -------------MLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPL 815
                            S+T  + +  + +      +S++ S  +  +E+T A TT+S  
Sbjct: 574 TTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSET 633

Query: 816 PPSLTESSTEQTLPATSTNLAQMSPT------------FTTTILKT-SQPLMTTPGTLSS 862
             + TE S   T+  T +    +S T             TTT+  T S+  ++T G+ ++
Sbjct: 634 TTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTT 693

Query: 863 TASLVTGPIAVQTTAGKQLSLTH---PEILVPQI--------STEGG----ISTERNRVI 907
           T S+        +T G + + T     EI    I        STEG      STE +   
Sbjct: 694 TVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETT 753

Query: 908 VDATTGLIPLTSVPTSAKEMTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSAT 967
             +TTG    T+  TS++  TT   +    +  + ++G+  +  +T  S    +  +++ 
Sbjct: 754 SASTTGSETTTASTTSSE--TTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSE 811

Query: 968 FAVQSSTQSPTTVSSSA 984
             + S+T S TT  S+A
Sbjct: 812 TTIASTTASETTTVSTA 828



 Score = 97.4 bits (241), Expect = 8e-20
 Identities = 205/912 (22%), Positives = 341/912 (37%), Gaps = 105/912 (11%)

Query: 121  VENITFYQNQEDFSTVSSK--EGVMVQTSGKSHAASDAPENLTLLAETADARGRSGSSSR 178
            +E  T      + +TVS+   E     T G    A+    + T    TAD+   + S++ 
Sbjct: 551  LETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTAD 610

Query: 179  TNFTILPVGYSLEIATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTA--SEMGT 236
            +  T          A+   S++   ++ S    ++S+E  E      T S T   S  G+
Sbjct: 611  SETTS---------ASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGS 661

Query: 237  ERAMGLSEEWTVHSQEATTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAAS 296
            ER +  +E       E TT + + S       G  TT      S    +S      T  S
Sbjct: 662  ERTITSTE-----GSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTS 716

Query: 297  SPLLDLSSSS-ESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVSK 355
            +   +++++S   +E    ST    ++ + T+     +  T G   T  S T S   ++ 
Sbjct: 717  TEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMAS 776

Query: 356  TEGFPKDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQND 415
              G   ++ +A+T  S     S   S+  +  T N   E  I  +T +E    S      
Sbjct: 777  IMG--SETTMASTIGSETTKVSTASSKMTTVFTEN--SETTIASTTASETTTVS------ 826

Query: 416  SPTFGEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADVTGSSAS 475
              T G   + +S+     +  + TE    + A   G E T     T ST S++ T ++  
Sbjct: 827  --TAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETT-----TASTESSETTTATTI 879

Query: 476  YPEGVNASVLTQFSDSTVQSG-GSHTALGDRSYSESS--STSSSESLNSSAPRGERSIAG 532
              E   AS  T+ S++T  S  GS T       SE +  ST+ SE+  +S    E + A 
Sbjct: 880  GSETTTAS--TEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAS 937

Query: 533  ISYGQVRGTAIEQRTSSDHTDHTYLSSTFTKGERALLSITDNSSSSDIVESSTSYIKISN 592
                ++  T +    S   T     S T T       + T +++ S+    ST+  + + 
Sbjct: 938  TEGSEL--TTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTT 995

Query: 593  SS--HSEYSSFFHAQTERSNISSYDGEYAQPSTESPVLHTSNLPSYTPTINMPNTSVVLD 650
            +S   SE ++     +E + +S+   E    STE     T        T      S    
Sbjct: 996  ASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTT 1055

Query: 651  TDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHH--LFSSILPSTRASVHLLKS-TSD 707
            T  E    ++ S++ S ++++S   L   +VS S      +S   S   +V++  S T+ 
Sbjct: 1056 TSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTT 1115

Query: 708  ASTPWSSSPSPLPVSLTTSTSAPLSVSQTTL--PQSSSTPVLPRARETPVTSFQTSTMTS 765
            AST  S + +    S  T+T++      TT+    S +T V     E   +S   S  T+
Sbjct: 1116 ASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATT 1175

Query: 766  FMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESSTE 825
              T    + TA      T       +E+ + S     +E+T A T+ S    + T  S  
Sbjct: 1176 TSTEGSETTTASTAGSETTTASTAGSETTTASTAG--SETTTASTSGSETNTACTTGSET 1233

Query: 826  QT---------------LPATSTNLAQMSPTF-------TTTILKTSQPLMTTPGTLSST 863
             T                  T  + A + PT        TTT+  T+        T+SST
Sbjct: 1234 STPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSST 1293

Query: 864  ASLVT------------GPIAVQTTAGKQLSLTHPEILVPQISTEGGISTERNRVIVDAT 911
              ++T             P++   T G +L+ +    + P +      ++     IV  T
Sbjct: 1294 TFVLTKATDVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMDFTASAASHTVPGIVLNT 1353

Query: 912  TGLIPLT---SVPTSAKEMTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSATF 968
            +GL   T   S  TSA  + T  G T E  P S              ST ++  P S   
Sbjct: 1354 SGLGTSTMGASSTTSAHGVRTTTGSTRE--PTS--------------STFQETGPVSMGT 1397

Query: 969  AVQSSTQSPTTV 980
               S + +PT V
Sbjct: 1398 NTVSMSHTPTNV 1409



 Score = 93.6 bits (231), Expect = 1e-18
 Identities = 138/603 (22%), Positives = 237/603 (39%), Gaps = 69/603 (11%)

Query: 445 SVAPMRGGEITAHWLLTNSTTSADVTGSSASYPE---------GVNASVLTQFS-----D 490
           + A   G E T   +  + TT+A   GS  + P           ++ S +T  S     +
Sbjct: 16  TTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSEN 75

Query: 491 STVQSGGSHTALGDRSYSESS-STSSSESLNSSAPRGERSIAGISYGQVRGTAIEQRTSS 549
           +TV S GS T     + SE++ ST+ SE+          SI G     V     E  T+S
Sbjct: 76  TTVSSAGSGTTTASMAGSETTVSTAGSETTTV-------SITGTETTMVSAMGSETTTNS 128

Query: 550 DHTDHTYLSSTFTKGERALLSITDNSSSSDIVESSTSYIKISNSSHSEYSSFFHAQTERS 609
             +  T ++ST       + ++   ++++   +S T+    ++++ SE ++ F A +E  
Sbjct: 129 TTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETT---AASTTGSEMTTVFTAGSETI 185

Query: 610 NISSYDGEYAQPST---ESPVLHTSNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSS 666
             S+   E    ST   E+  + T+   + T +     T+      +E    S++ S ++
Sbjct: 186 TPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETT 245

Query: 667 SSSSSSGPPLPLPSVSQSHHLFSSILPSTRASVHLLKSTSDASTPWSSSPSPLPVSLTTS 726
            S++ S         S+++  F+    +T AS    ++T+ AST  S       +   T+
Sbjct: 246 VSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTA-ASTTGSEPTMASTMGSETT 304

Query: 727 TSAPLSVSQTTLPQSSS--TPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADL-----K 779
            ++ +    T +  +SS  T V     ET   S   S  T+  T    + TA +      
Sbjct: 305 MASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETS 364

Query: 780 SQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESSTEQTLPATSTNLAQMS 839
           + ST   E     ++     +  TE ++A T ++    + T S T+     T T  ++M+
Sbjct: 365 TDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMT 424

Query: 840 PTFTT--------------TILKTSQPLMTTPGTLSSTASLVT----GPIAVQTTAGKQL 881
              TT              TI  TS    TT  T  S  + VT          TT  +  
Sbjct: 425 AVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETT 484

Query: 882 SLTHPEILVPQISTEGG----ISTERNRVIVDATTGLIPLTSVPTSAKEMTTKLGVTAEY 937
           + ++  +    + T G      STE +     + TG   +T+V T   E TT     +E 
Sbjct: 485 TASNTGLETTTVFTIGSDTTTASTEGSETTAVSATG-SEMTTVSTEGSENTTVSTTGSET 543

Query: 938 SPAS------RSLGTSPSPQTTV----VSTAEDLAPKSATFAVQSSTQSPTTVSSSASVN 987
           +  S       +  T  S  TTV      T  D    S T A  ++    TTVS++ S N
Sbjct: 544 TTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSEN 603

Query: 988 SCA 990
           + A
Sbjct: 604 TTA 606



 Score = 63.9 bits (154), Expect = 1e-09
 Identities = 137/617 (22%), Positives = 220/617 (35%), Gaps = 62/617 (10%)

Query: 46   PLAGAGLELQLERRPEREPPPTPPRERRGPATPGPSYRAPEPGAATQRGP-SGRAPRGGS 104
            P + AG E       E     T   E  G  T   S  + E   AT  G  +  A   GS
Sbjct: 834  PASTAGSETTTTTSTEGSETTTASTE--GSETTTASTESSETTTATTIGSETTTASTEGS 891

Query: 105  ADAAWKHWPESNTEAHVEN--ITFYQNQEDFSTVSSKEGVMVQTSGKSHAASDAPENLTL 162
                        T A  E   IT        +T +S EG    T      AS     LT 
Sbjct: 892  ETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTT------ASTEGSELTT 945

Query: 163  LAETADARGRSGSSSRTNFTILPVGYSLEIATALTSQSGNLASESLHLPSSSSEFDERIA 222
            ++ T        +      T+  +G     A+   S++  +++      ++S E  E   
Sbjct: 946  VSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTT 1005

Query: 223  AFQTKSGTA--SEMGTERAMGLSEEWTVHSQEATTSAWSPSFLPAL-EMGELTTPSRKRN 279
               T S T   S  GTE  +  +E       E TT   + S   A+   G  TT +    
Sbjct: 1006 VSSTGSETTTVSTTGTETTITSTE-----GSETTTVTTAGSETTAVYTTGSETTTTSTEG 1060

Query: 280  SSGPDLSWLHFYRTAASSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVA-----TV 334
            S    +S      T AS+   DL +++ ST     +T   S++ S+T T+++      T 
Sbjct: 1061 SETTTVSTTGSETTTASTA--DLETTTVSTSGSGTTTA--STAGSETTTVYITGSKTTTA 1116

Query: 335  FTDGGPRTLRSLTVSLGPVSKTEGFPKDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDE 394
             T+G   T  S T S    + T G    +   T S +  +S    E+      T +    
Sbjct: 1117 STEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEA-----TTSSAAGS 1171

Query: 395  EFIEPSTENEFGLTSLRWQNDSPTFGEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEI 454
            E    STE     T+               A S      +  S+T T S +     G E 
Sbjct: 1172 EATTTSTEGSETTTA-------------STAGSETTTASTAGSETTTASTA-----GSET 1213

Query: 455  TAHWLLTNSTTSADVTGSSASYPEGVNASVLTQFSDSTVQSGGSHTALGDRSYSESSSTS 514
            T      + T +A  TGS  S P    +   T F   +  +  S  +L   + S + S +
Sbjct: 1214 TTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSET 1273

Query: 515  SSESLNSS-APRGERSIAGISYGQVRGTAIEQRTSSDHTDHTYLSSTFTKGERALLSIT- 572
            ++ S+ +S A     +++  ++   + T +    S     +T +S T T G R   S + 
Sbjct: 1274 TTVSITASGATAASTTVSSTTFVLTKATDV----SIQPITNTPMSGTRTTGTRLTASSSV 1329

Query: 573  DNSSSSDIVESSTSY----IKISNSSHSEYSSFFHAQTERSNISSYDGEYAQPSTESPVL 628
              +   D   S+ S+    I ++ S     +    + T    + +  G   +P T S   
Sbjct: 1330 TMAPGMDFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGSTREP-TSSTFQ 1388

Query: 629  HTSNLPSYTPTINMPNT 645
             T  +   T T++M +T
Sbjct: 1389 ETGPVSMGTNTVSMSHT 1405



 Score = 61.2 bits (147), Expect = 6e-09
 Identities = 106/542 (19%), Positives = 202/542 (37%), Gaps = 41/542 (7%)

Query: 644  NTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSILPSTRASVHLLK 703
            NT+    T +E  +     +S ++++S++G     PS + S    ++I+  + + +    
Sbjct: 14   NTTTASTTGSE-TTTILIKASETTTASTAGSETTTPSPTGSQ---TTIVSISGSEITTTS 69

Query: 704  STSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQSSSTPVLPRARETPVTSFQTSTM 763
            +    +T  SS+ S      TT++ A    + +T    ++T  +     T V++  + T 
Sbjct: 70   TAGSENTTVSSAGS----GTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETT 125

Query: 764  TSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESS 823
            T+  T   ++ T+   S++T         S++ +  +  +E+T A TT S +    T  S
Sbjct: 126  TNSTTSSETTVTSTAGSETTTVS---TVGSETTTAYTADSETTAASTTGSEMTTVFTAGS 182

Query: 824  TEQTLPATSTNLAQMSPTFTTTILKTSQPLMTTPGTLSSTASLVTGPIAVQTTAGKQLSL 883
             E   P+T+      S T T +   +    ++T G+ ++TAS         +T G + + 
Sbjct: 183  -ETITPSTAG-----SETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTK 236

Query: 884  THPEILVPQISTEGGIST-------ERNRVIV-DATTGLIPLTSVPTSAKEMTTKLGVTA 935
                     +ST G  +T       E N     D+ T     T   T+A   T      A
Sbjct: 237  VSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMA 296

Query: 936  EYSPASRSLGTSPSPQTTVVSTAED-----LAPKSATFAVQSSTQSPTTVSSSASVNSCA 990
                +  ++ ++  P+TT VSTA        A  S T    +     TTVS++ S  + A
Sbjct: 297  STMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTA 356

Query: 991  VNPCLHNGECVADNTSRGYHCRCPPSWQGDDCSVDVNE-----CLSNPCPSTAMCNNTQG 1045
                +   E   D+T+         S +G + +    E      +S     T   + T  
Sbjct: 357  ---SIMGSETSTDSTTGSE--TTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDS 411

Query: 1046 SFICKCPVGYQLEKGICNLVRTFVTEFKLKRTFLNTTVEKHSDLQEVENEITKTLNMCFS 1105
                 C  G ++      +  T     +     + +T +  +     E   T T+    S
Sbjct: 412  ETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGS 471

Query: 1106 ALPSYIRSTVHASRESNAVVISLQTTFSLASNVTLFDLADRMQKCVNSCKSSAEVCQLLG 1165
               +   +    +  SN   +   T F++ S+ T           V++  S        G
Sbjct: 472  ETKTAYTTGSETTTASN-TGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEG 530

Query: 1166 SQ 1167
            S+
Sbjct: 531  SE 532


>gi|239740645 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score =  134 bits (336), Expect = 8e-31
 Identities = 217/904 (24%), Positives = 370/904 (40%), Gaps = 98/904 (10%)

Query: 134 STVSSKEGVMVQTSGKSHAASDAPENLTLLAETAD----ARGRSGSSSRTNFTILPVGYS 189
           ++ +S E  +  T+G          + T  A TAD    A   +GS   T FT      +
Sbjct: 127 NSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETIT 186

Query: 190 LEIATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTASEMGTERAMGLSEEWTVH 249
              A + T+      SE+  + ++ SE      A  +++  AS MG+E     ++  T  
Sbjct: 187 PSTAGSETTTVSTAGSETTTVSTTGSETTTASTA-HSETTAASTMGSE----TTKVSTAG 241

Query: 250 SQEATTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASS----PLLDLSSS 305
           S+   ++A S +   + E  E T  +   +S     S   F  TAAS+    P +  +  
Sbjct: 242 SETTVSTAGSETTAASTEDSE-TNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMG 300

Query: 306 SESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVSKTEGFPKDSRI 365
           SE+T  + ++ G +++ VS T +  V TVF   G  T+R+ TV  G  + T      +  
Sbjct: 301 SETT--MASTIGPETTKVS-TASSEVTTVFA-AGSETIRASTV--GSETTT---VSTTGS 351

Query: 366 ATTSSSVLLSPSAVESRRNSR-VTGNPGDEEFIEPSTENEFGLTSLRWQNDSPTFGEHQL 424
            TT++S++ S ++ +S   S   T +    E    STE     T     +++ T      
Sbjct: 352 ETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDS 411

Query: 425 ASSSEVQNGSPMSQTETV--SRSVAPMRGGEITAHWLLTNSTTSADVTGSSASYPEGVNA 482
            +++    GS M+   T     + A   G EIT      + TT+A   GS  +      +
Sbjct: 412 ETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGS 471

Query: 483 SVLTQFSDSTVQSGGSHTALGDR------SYSESSSTSSSESLNSSAPRGER---SIAGI 533
              T ++  +  +  S+T L         S + ++ST  SE+   SA   E    S  G 
Sbjct: 472 ETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGS 531

Query: 534 SYGQVRGTAIEQRTSSDHTDHTYLSSTFTKG-ERALLSITDNSSSSDIVESSTSYIKISN 592
               V  T  E  T S  T     ++T T+G E   +S T   +++D  E S +    ++
Sbjct: 532 ENTTVSTTGSETTTVS--TTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGT--TAAS 587

Query: 593 SSHSEYSSFFHAQTERSNISSYDGEYAQPST---ESPVLHTSNLPSYTPTINMPNTSVVL 649
           ++ SE ++   A +E +  S+ D E    ST   E+    T++  + T +     T+ V 
Sbjct: 588 TAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVS 647

Query: 650 DTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSILPSTRASVHLLKSTSDAS 709
            TD+E    S++ S  + +S+       + +      + +    +T  S+     T   +
Sbjct: 648 TTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSI-----TGSET 702

Query: 710 TPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQSSSTPVLPRARETPVTSFQTSTMTSFMTM 769
           T  S++ S      TT+++    ++  ++  S +T       ET   S + S  TS  T 
Sbjct: 703 TKVSTTGS----ETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTT 758

Query: 770 LHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESST----- 824
              + TA   S  T     + +E+   S +   +E+TK  T +S +    TE+S      
Sbjct: 759 GSETTTASTTSSETTMASIMGSETTMASTIG--SETTKVSTASSKMTTVFTENSETTIAS 816

Query: 825 -------------EQTLPATSTNLAQMSPTFTTTILKTSQ-PLMTTPGTLSSTASLVTGP 870
                         +T+PA++      S T TTT  + S+    +T G+ ++TAS  +  
Sbjct: 817 TTASETTTVSTAGSETIPASTAG----SETTTTTSTEGSETTTASTEGSETTTASTESSE 872

Query: 871 IAVQTTAGKQLSLTHPEILVPQISTEGG----ISTERNRVIVDATTGLIPLTSVPTSAKE 926
               TT G + +           STEG      STE +     +T G   +T+V T+  E
Sbjct: 873 TTTATTIGSETTTA---------STEGSETTTTSTEGSETTTASTEG-SEITTVSTTGSE 922

Query: 927 MTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSATFAVQSSTQSPTTVSSSASV 986
            TT     +E + AS    T  S  TTV +T  +    SA     S T + TT+ S  + 
Sbjct: 923 TTTASTEGSETTTAS----TEGSELTTVSTTGSETITVSAE---GSETTTVTTMGSETTT 975

Query: 987 NSCA 990
            S A
Sbjct: 976 ASTA 979



 Score =  128 bits (321), Expect = 4e-29
 Identities = 209/911 (22%), Positives = 353/911 (38%), Gaps = 84/911 (9%)

Query: 114  ESNTEAHVENITFYQNQEDFSTVSSKEGVMVQTSGKSHAASDAPENLTLLAETADARGRS 173
            +S T +     +   ++   ++    E   V T+G         ++ T    T  +   +
Sbjct: 366  DSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTA 425

Query: 174  GSSSRTNFTILPV-GYSLEIATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTAS 232
             S++    T     G  + IA+   S++   ++E     + ++   E   A+ T S T +
Sbjct: 426  VSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTT 485

Query: 233  EMGTERAMGLSEEWTVHSQEATTSAWSPSFLPALEMG-ELTTPSRKRNSSGPDLSWLHFY 291
               T   +  +  +T+ S   T S            G E+TT S + + +    +     
Sbjct: 486  ASNT--GLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSET 543

Query: 292  RTAASSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLG 351
             T +++ L   ++S+E +E    ST    ++   T+        T G   T    TVS  
Sbjct: 544  TTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETT----TVSTA 599

Query: 352  PVSKTEGFPKDSRIATTSSSVLLSPSAVESRRNSRVT--GNPGDEEFIEPSTENEFGLTS 409
                T     DS   TTS+S   S +   S  +S  T     G E     +T++E  + S
Sbjct: 600  DSENTTASTADSE--TTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVS 657

Query: 410  LRWQNDSPTFGEHQLASSSEVQNGSPMSQT---ETVSRSVAPMRGGEITAHWLLTNSTTS 466
                    T G  +  +S+E    + +S T    TVS   +      IT       STT 
Sbjct: 658  --------TTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTG 709

Query: 467  ADVTGSSASYPEGVNASVLTQFSDSTVQSGGSHTALGDRSYSE--SSSTSSSESLNSSAP 524
            ++ T +S    E   AS+ T    +T  + GS T       SE  S+ST+ SE+  +S  
Sbjct: 710  SETTTTSTEGSEITTASI-TGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTT 768

Query: 525  RGERSIAGISYGQVR-GTAIEQRTSSDHTDHTYLSSTFTKGERALLSITDNSSSSDIVES 583
              E ++A I   +    + I   T+   T  + +++ FT+     ++ T  S ++ +  +
Sbjct: 769  SSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTA 828

Query: 584  STSYIKISNSSHSEYSSFFHAQTERSNISSYDGEYAQPSTESPVLHTSNLPSYTPTINMP 643
             +  I  S +     ++     +E +  S+   E    STES    T+       TI   
Sbjct: 829  GSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTAT------TIGSE 882

Query: 644  NTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSI------LPSTRA 697
             T+    T+    + +S+  S ++++S+ G  +   S + S    +S         ST  
Sbjct: 883  TTTA--STEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEG 940

Query: 698  SVHLLKSTSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQSSSTPVLPRARETPVTS 757
            S     ST+ + T   S+      ++TT  S   + S      S +T V     ET   S
Sbjct: 941  SELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAG---SETTTVSTAGSETTTAS 997

Query: 758  FQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPT---ESTKAVTTNSP 814
             + S  T+      SS  ++  + ST   E  IT ++     ++ T   E+T   TT S 
Sbjct: 998  IEGSETTTV-----SSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSE 1052

Query: 815  LPPSLTESSTEQTLPATSTNLAQMSPT-FTTTILKTSQPLMTTPGTLSSTASLVTGPIAV 873
               + TE S   T+  T +     S     TT + TS    TT  T  S  + V    + 
Sbjct: 1053 TTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSK 1112

Query: 874  QTTAGKQLSLTHPEILVPQISTEGG----ISTERNRVIVDATTGLIPLTSVPTSAKEMTT 929
             TTA                STEG     +ST  +     +TTG   +T+V T+  E TT
Sbjct: 1113 TTTA----------------STEGSEATTVSTTSSETTTASTTG-SEMTTVFTTVSETTT 1155

Query: 930  --KLGVTAEYSPASRSLGTSPS---PQTTVVSTAEDLAPKSATFAVQSSTQS-----PTT 979
               +G  A  S A+ S  T+ S    +TT  STA      ++T   +++T S      TT
Sbjct: 1156 VSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTAGSETTT 1215

Query: 980  VSSSASVNSCA 990
             S+S S  + A
Sbjct: 1216 ASTSGSETNTA 1226



 Score =  118 bits (296), Expect = 3e-26
 Identities = 200/902 (22%), Positives = 348/902 (38%), Gaps = 74/902 (8%)

Query: 134  STVSSKEGVMVQTSG-KSHAASDAPENLTLLAETADARGRSGSSSRTNFTILPVGYSLEI 192
            ST+ S E  M  T G ++   S A   +T +        R+ +      T+   G     
Sbjct: 297  STMGS-ETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTT 355

Query: 193  ATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTASEMGTERAMGLSEEWTVH--S 250
            A+ + S++   ++      ++S+E  E   A    S   SE  T    G SE  TV    
Sbjct: 356  ASIMGSETSTDSTTGSETTTASTEGSETTTA----STEGSEATTVSTTG-SETTTVSITD 410

Query: 251  QEATTSAWSPSFLPAL------------EMGELT---TPSRKRNSSGPDLSWLHFYRTAA 295
             E TT+    S + A+            E  E+T   T   +  ++  + S      TA 
Sbjct: 411  SETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAG 470

Query: 296  SSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVSK 355
            S      ++ SE+T   N  TGL++++V  T      T  T+G   T  S T S      
Sbjct: 471  SETKTAYTTGSETTTASN--TGLETTTVF-TIGSDTTTASTEGSETTAVSATGSEMTTVS 527

Query: 356  TEGFPKDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQND 415
            TEG    +   T S +  +S + +E+   S         E  E +T +  G  +     +
Sbjct: 528  TEGSENTTVSTTGSETTTVSTTGLETTTTST--------EGSEMTTVSTTGAETTTDSTE 579

Query: 416  SPTFGEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADVTGSSAS 475
                     A S      +  S+  T S + +       T     T STTS++ T +S  
Sbjct: 580  GSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTE 639

Query: 476  YPEGVNASVLTQFSDSTVQSGGSHTALGDRSYSESSSTSSSESLNSSAPRGER----SIA 531
              E    S  T    + V + GS   +     SE+++ S++ S  + +  G      SI 
Sbjct: 640  GSETTTVST-TDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSIT 698

Query: 532  GISYGQVRGTAIEQRTSSDHTDHTYLSS--------TFTKGERALLSITDNS--SSSDIV 581
            G    +V  T  E  T+S        +S          T+G     + T+ S  +S+   
Sbjct: 699  GSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTT 758

Query: 582  ESSTSYIKISNSSHSEYSSFFHAQTERSNISSYDGEYAQPSTESPVLHTSNLPSYTPTIN 641
             S T+    ++S  +  S      T  S I S   + +  S++   + T N  +   +  
Sbjct: 759  GSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTT 818

Query: 642  MPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSILPS-TRASVH 700
               T+ V    +E +  S++ S +++++S+ G      S   S    +S   S T  +  
Sbjct: 819  ASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATT 878

Query: 701  LLKSTSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQ--SSSTPVLPRARETPVTSF 758
            +   T+ AST  S + +       T+T++      TT+    S +T       ET   S 
Sbjct: 879  IGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAST 938

Query: 759  QTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPS 818
            + S +T+  T    S+T  + ++ +         S++ +  +  +E+T   T  S    +
Sbjct: 939  EGSELTTVSTT--GSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTA 996

Query: 819  LTESSTEQTLPATSTNLAQMSPTFTTTILKTSQPLMTTPGTLSSTASLVTGPIAVQTTAG 878
              E S   T+ +T +    +S T T T + +++   TT  T+++  S  T   AV TT  
Sbjct: 997  SIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETT--TVTTAGSETT---AVYTTGS 1051

Query: 879  KQLSLTHPEILVPQISTEGGISTERNRVIVDATTGLIP---LTSVPTSAKEMTTKLGVTA 935
            +  + +        +ST G  +T  +   ++ TT        T+  T+  E TT     +
Sbjct: 1052 ETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGS 1111

Query: 936  EYSPASRSLGTSPSPQTTVVSTAEDLAPKSAT-------FAVQSSTQSPTTVSSSASVNS 988
            + + AS    T  S  TTV +T+ +    S T       F   S T + +T+ S A+ +S
Sbjct: 1112 KTTTAS----TEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSS 1167

Query: 989  CA 990
             A
Sbjct: 1168 AA 1169



 Score =  105 bits (261), Expect = 4e-22
 Identities = 191/857 (22%), Positives = 342/857 (39%), Gaps = 147/857 (17%)

Query: 230 TASEMGTERAMGLSEEWTVHSQEATTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLH 289
           TAS  G+E    L     + + E TT++ + S        E TTPS       P  S   
Sbjct: 17  TASTTGSETTTIL-----IKASETTTASTAGS--------ETTTPS-------PTGSQTT 56

Query: 290 FYRTAASSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVS 349
               + S      ++ SE+T   +  +G  ++S++ ++T    TV T G   T  S+T +
Sbjct: 57  IVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSET----TVSTAGSETTTVSITGT 112

Query: 350 LGPVSKTEGFPKDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTS 409
              +    G    +   T+S + + S +  E+   S V    G E     + ++E    S
Sbjct: 113 ETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTV----GSETTTAYTADSETTAAS 168

Query: 410 LRWQNDSPTFGEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADV 469
                 +  F     A S  +   +  S+T TVS +     G E T     T STT ++ 
Sbjct: 169 TTGSEMTTVF----TAGSETITPSTAGSETTTVSTA-----GSETT-----TVSTTGSET 214

Query: 470 TGSSASYPEGVNAS--------VLTQFSDSTVQSGGS------------HTALGDRSYSE 509
           T +S ++ E   AS        V T  S++TV + GS            +TA  + S + 
Sbjct: 215 TTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTT 274

Query: 510 SSSTSSSESLNSSAPRGERSIAGISYGQ-VRGTAIEQRTSSDHTDHTYLSSTFTKGERAL 568
           ++ST+  E+  +S    E ++A     +    + I   T+   T  + +++ F  G   +
Sbjct: 275 TASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETI 334

Query: 569 LSITDNSSSSDIVESSTSYIKISNSSHSEYSSFFHAQTERSNISSYDGEYAQPSTE-SPV 627
            + T  S ++  V ++ S    ++   SE S+     +E +  S+   E    STE S  
Sbjct: 335 RASTVGSETT-TVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEA 393

Query: 628 LHTSNLPSYTPTINMPNT---------------------SVVLDTDAEFVSDSSSSSSSS 666
              S   S T T+++ ++                     +    T+   ++ +S+S S +
Sbjct: 394 TTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSET 453

Query: 667 SSSSSSGPPLPLPSV--SQSHHLFSSILPSTRASVHLLKST------SDASTPWSSSPSP 718
           +++S+ G      +   S++   +++   +T AS   L++T      SD +T  +     
Sbjct: 454 TTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSET 513

Query: 719 LPVSLTTSTSAPLSV---SQTTLPQ--SSSTPVLPRARETPVTSFQTSTMTSFMT----- 768
             VS T S    +S      TT+    S +T V     ET  TS + S MT+  T     
Sbjct: 514 TAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAET 573

Query: 769 -------------MLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPL 815
                            S+T  + +  + +      +S++ S  +  +E+T A TT+S  
Sbjct: 574 TTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSET 633

Query: 816 PPSLTESSTEQTLPATSTNLAQMSPT------------FTTTILKT-SQPLMTTPGTLSS 862
             + TE S   T+  T +    +S T             TTT+  T S+  ++T G+ ++
Sbjct: 634 TTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTT 693

Query: 863 TASLVTGPIAVQTTAGKQLSLTH---PEILVPQI--------STEGG----ISTERNRVI 907
           T S+        +T G + + T     EI    I        STEG      STE +   
Sbjct: 694 TVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETT 753

Query: 908 VDATTGLIPLTSVPTSAKEMTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSAT 967
             +TTG    T+  TS++  TT   +    +  + ++G+  +  +T  S    +  +++ 
Sbjct: 754 SASTTGSETTTASTTSSE--TTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSE 811

Query: 968 FAVQSSTQSPTTVSSSA 984
             + S+T S TT  S+A
Sbjct: 812 TTIASTTASETTTVSTA 828



 Score = 97.4 bits (241), Expect = 8e-20
 Identities = 205/912 (22%), Positives = 341/912 (37%), Gaps = 105/912 (11%)

Query: 121  VENITFYQNQEDFSTVSSK--EGVMVQTSGKSHAASDAPENLTLLAETADARGRSGSSSR 178
            +E  T      + +TVS+   E     T G    A+    + T    TAD+   + S++ 
Sbjct: 551  LETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTAD 610

Query: 179  TNFTILPVGYSLEIATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTA--SEMGT 236
            +  T          A+   S++   ++ S    ++S+E  E      T S T   S  G+
Sbjct: 611  SETTS---------ASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGS 661

Query: 237  ERAMGLSEEWTVHSQEATTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAAS 296
            ER +  +E       E TT + + S       G  TT      S    +S      T  S
Sbjct: 662  ERTITSTE-----GSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTS 716

Query: 297  SPLLDLSSSS-ESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVSK 355
            +   +++++S   +E    ST    ++ + T+     +  T G   T  S T S   ++ 
Sbjct: 717  TEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMAS 776

Query: 356  TEGFPKDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQND 415
              G   ++ +A+T  S     S   S+  +  T N   E  I  +T +E    S      
Sbjct: 777  IMG--SETTMASTIGSETTKVSTASSKMTTVFTEN--SETTIASTTASETTTVS------ 826

Query: 416  SPTFGEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADVTGSSAS 475
              T G   + +S+     +  + TE    + A   G E T     T ST S++ T ++  
Sbjct: 827  --TAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETT-----TASTESSETTTATTI 879

Query: 476  YPEGVNASVLTQFSDSTVQSG-GSHTALGDRSYSESS--STSSSESLNSSAPRGERSIAG 532
              E   AS  T+ S++T  S  GS T       SE +  ST+ SE+  +S    E + A 
Sbjct: 880  GSETTTAS--TEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAS 937

Query: 533  ISYGQVRGTAIEQRTSSDHTDHTYLSSTFTKGERALLSITDNSSSSDIVESSTSYIKISN 592
                ++  T +    S   T     S T T       + T +++ S+    ST+  + + 
Sbjct: 938  TEGSEL--TTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTT 995

Query: 593  SS--HSEYSSFFHAQTERSNISSYDGEYAQPSTESPVLHTSNLPSYTPTINMPNTSVVLD 650
            +S   SE ++     +E + +S+   E    STE     T        T      S    
Sbjct: 996  ASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTT 1055

Query: 651  TDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHH--LFSSILPSTRASVHLLKS-TSD 707
            T  E    ++ S++ S ++++S   L   +VS S      +S   S   +V++  S T+ 
Sbjct: 1056 TSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTT 1115

Query: 708  ASTPWSSSPSPLPVSLTTSTSAPLSVSQTTL--PQSSSTPVLPRARETPVTSFQTSTMTS 765
            AST  S + +    S  T+T++      TT+    S +T V     E   +S   S  T+
Sbjct: 1116 ASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATT 1175

Query: 766  FMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESSTE 825
              T    + TA      T       +E+ + S     +E+T A T+ S    + T  S  
Sbjct: 1176 TSTEGSETTTASTAGSETTTASTAGSETTTASTAG--SETTTASTSGSETNTACTTGSET 1233

Query: 826  QT---------------LPATSTNLAQMSPTF-------TTTILKTSQPLMTTPGTLSST 863
             T                  T  + A + PT        TTT+  T+        T+SST
Sbjct: 1234 STPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSST 1293

Query: 864  ASLVT------------GPIAVQTTAGKQLSLTHPEILVPQISTEGGISTERNRVIVDAT 911
              ++T             P++   T G +L+ +    + P +      ++     IV  T
Sbjct: 1294 TFVLTKATDVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMDFTASAASHTVPGIVLNT 1353

Query: 912  TGLIPLT---SVPTSAKEMTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSATF 968
            +GL   T   S  TSA  + T  G T E  P S              ST ++  P S   
Sbjct: 1354 SGLGTSTMGASSTTSAHGVRTTTGSTRE--PTS--------------STFQETGPVSMGT 1397

Query: 969  AVQSSTQSPTTV 980
               S + +PT V
Sbjct: 1398 NTVSMSHTPTNV 1409



 Score = 93.6 bits (231), Expect = 1e-18
 Identities = 138/603 (22%), Positives = 237/603 (39%), Gaps = 69/603 (11%)

Query: 445 SVAPMRGGEITAHWLLTNSTTSADVTGSSASYPE---------GVNASVLTQFS-----D 490
           + A   G E T   +  + TT+A   GS  + P           ++ S +T  S     +
Sbjct: 16  TTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSEN 75

Query: 491 STVQSGGSHTALGDRSYSESS-STSSSESLNSSAPRGERSIAGISYGQVRGTAIEQRTSS 549
           +TV S GS T     + SE++ ST+ SE+          SI G     V     E  T+S
Sbjct: 76  TTVSSAGSGTTTASMAGSETTVSTAGSETTTV-------SITGTETTMVSAMGSETTTNS 128

Query: 550 DHTDHTYLSSTFTKGERALLSITDNSSSSDIVESSTSYIKISNSSHSEYSSFFHAQTERS 609
             +  T ++ST       + ++   ++++   +S T+    ++++ SE ++ F A +E  
Sbjct: 129 TTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETT---AASTTGSEMTTVFTAGSETI 185

Query: 610 NISSYDGEYAQPST---ESPVLHTSNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSS 666
             S+   E    ST   E+  + T+   + T +     T+      +E    S++ S ++
Sbjct: 186 TPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETT 245

Query: 667 SSSSSSGPPLPLPSVSQSHHLFSSILPSTRASVHLLKSTSDASTPWSSSPSPLPVSLTTS 726
            S++ S         S+++  F+    +T AS    ++T+ AST  S       +   T+
Sbjct: 246 VSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTA-ASTTGSEPTMASTMGSETT 304

Query: 727 TSAPLSVSQTTLPQSSS--TPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADL-----K 779
            ++ +    T +  +SS  T V     ET   S   S  T+  T    + TA +      
Sbjct: 305 MASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETS 364

Query: 780 SQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESSTEQTLPATSTNLAQMS 839
           + ST   E     ++     +  TE ++A T ++    + T S T+     T T  ++M+
Sbjct: 365 TDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMT 424

Query: 840 PTFTT--------------TILKTSQPLMTTPGTLSSTASLVT----GPIAVQTTAGKQL 881
              TT              TI  TS    TT  T  S  + VT          TT  +  
Sbjct: 425 AVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETT 484

Query: 882 SLTHPEILVPQISTEGG----ISTERNRVIVDATTGLIPLTSVPTSAKEMTTKLGVTAEY 937
           + ++  +    + T G      STE +     + TG   +T+V T   E TT     +E 
Sbjct: 485 TASNTGLETTTVFTIGSDTTTASTEGSETTAVSATG-SEMTTVSTEGSENTTVSTTGSET 543

Query: 938 SPAS------RSLGTSPSPQTTV----VSTAEDLAPKSATFAVQSSTQSPTTVSSSASVN 987
           +  S       +  T  S  TTV      T  D    S T A  ++    TTVS++ S N
Sbjct: 544 TTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSEN 603

Query: 988 SCA 990
           + A
Sbjct: 604 TTA 606



 Score = 63.9 bits (154), Expect = 1e-09
 Identities = 137/617 (22%), Positives = 220/617 (35%), Gaps = 62/617 (10%)

Query: 46   PLAGAGLELQLERRPEREPPPTPPRERRGPATPGPSYRAPEPGAATQRGP-SGRAPRGGS 104
            P + AG E       E     T   E  G  T   S  + E   AT  G  +  A   GS
Sbjct: 834  PASTAGSETTTTTSTEGSETTTASTE--GSETTTASTESSETTTATTIGSETTTASTEGS 891

Query: 105  ADAAWKHWPESNTEAHVEN--ITFYQNQEDFSTVSSKEGVMVQTSGKSHAASDAPENLTL 162
                        T A  E   IT        +T +S EG    T      AS     LT 
Sbjct: 892  ETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTT------ASTEGSELTT 945

Query: 163  LAETADARGRSGSSSRTNFTILPVGYSLEIATALTSQSGNLASESLHLPSSSSEFDERIA 222
            ++ T        +      T+  +G     A+   S++  +++      ++S E  E   
Sbjct: 946  VSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTT 1005

Query: 223  AFQTKSGTA--SEMGTERAMGLSEEWTVHSQEATTSAWSPSFLPAL-EMGELTTPSRKRN 279
               T S T   S  GTE  +  +E       E TT   + S   A+   G  TT +    
Sbjct: 1006 VSSTGSETTTVSTTGTETTITSTE-----GSETTTVTTAGSETTAVYTTGSETTTTSTEG 1060

Query: 280  SSGPDLSWLHFYRTAASSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVA-----TV 334
            S    +S      T AS+   DL +++ ST     +T   S++ S+T T+++      T 
Sbjct: 1061 SETTTVSTTGSETTTASTA--DLETTTVSTSGSGTTTA--STAGSETTTVYITGSKTTTA 1116

Query: 335  FTDGGPRTLRSLTVSLGPVSKTEGFPKDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDE 394
             T+G   T  S T S    + T G    +   T S +  +S    E+      T +    
Sbjct: 1117 STEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEA-----TTSSAAGS 1171

Query: 395  EFIEPSTENEFGLTSLRWQNDSPTFGEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEI 454
            E    STE     T+               A S      +  S+T T S +     G E 
Sbjct: 1172 EATTTSTEGSETTTA-------------STAGSETTTASTAGSETTTASTA-----GSET 1213

Query: 455  TAHWLLTNSTTSADVTGSSASYPEGVNASVLTQFSDSTVQSGGSHTALGDRSYSESSSTS 514
            T      + T +A  TGS  S P    +   T F   +  +  S  +L   + S + S +
Sbjct: 1214 TTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSET 1273

Query: 515  SSESLNSS-APRGERSIAGISYGQVRGTAIEQRTSSDHTDHTYLSSTFTKGERALLSIT- 572
            ++ S+ +S A     +++  ++   + T +    S     +T +S T T G R   S + 
Sbjct: 1274 TTVSITASGATAASTTVSSTTFVLTKATDV----SIQPITNTPMSGTRTTGTRLTASSSV 1329

Query: 573  DNSSSSDIVESSTSY----IKISNSSHSEYSSFFHAQTERSNISSYDGEYAQPSTESPVL 628
              +   D   S+ S+    I ++ S     +    + T    + +  G   +P T S   
Sbjct: 1330 TMAPGMDFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGSTREP-TSSTFQ 1388

Query: 629  HTSNLPSYTPTINMPNT 645
             T  +   T T++M +T
Sbjct: 1389 ETGPVSMGTNTVSMSHT 1405



 Score = 61.2 bits (147), Expect = 6e-09
 Identities = 106/542 (19%), Positives = 202/542 (37%), Gaps = 41/542 (7%)

Query: 644  NTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSILPSTRASVHLLK 703
            NT+    T +E  +     +S ++++S++G     PS + S    ++I+  + + +    
Sbjct: 14   NTTTASTTGSE-TTTILIKASETTTASTAGSETTTPSPTGSQ---TTIVSISGSEITTTS 69

Query: 704  STSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQSSSTPVLPRARETPVTSFQTSTM 763
            +    +T  SS+ S      TT++ A    + +T    ++T  +     T V++  + T 
Sbjct: 70   TAGSENTTVSSAGS----GTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETT 125

Query: 764  TSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESS 823
            T+  T   ++ T+   S++T         S++ +  +  +E+T A TT S +    T  S
Sbjct: 126  TNSTTSSETTVTSTAGSETTTVS---TVGSETTTAYTADSETTAASTTGSEMTTVFTAGS 182

Query: 824  TEQTLPATSTNLAQMSPTFTTTILKTSQPLMTTPGTLSSTASLVTGPIAVQTTAGKQLSL 883
             E   P+T+      S T T +   +    ++T G+ ++TAS         +T G + + 
Sbjct: 183  -ETITPSTAG-----SETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTK 236

Query: 884  THPEILVPQISTEGGIST-------ERNRVIV-DATTGLIPLTSVPTSAKEMTTKLGVTA 935
                     +ST G  +T       E N     D+ T     T   T+A   T      A
Sbjct: 237  VSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMA 296

Query: 936  EYSPASRSLGTSPSPQTTVVSTAED-----LAPKSATFAVQSSTQSPTTVSSSASVNSCA 990
                +  ++ ++  P+TT VSTA        A  S T    +     TTVS++ S  + A
Sbjct: 297  STMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTA 356

Query: 991  VNPCLHNGECVADNTSRGYHCRCPPSWQGDDCSVDVNE-----CLSNPCPSTAMCNNTQG 1045
                +   E   D+T+         S +G + +    E      +S     T   + T  
Sbjct: 357  ---SIMGSETSTDSTTGSE--TTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDS 411

Query: 1046 SFICKCPVGYQLEKGICNLVRTFVTEFKLKRTFLNTTVEKHSDLQEVENEITKTLNMCFS 1105
                 C  G ++      +  T     +     + +T +  +     E   T T+    S
Sbjct: 412  ETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGS 471

Query: 1106 ALPSYIRSTVHASRESNAVVISLQTTFSLASNVTLFDLADRMQKCVNSCKSSAEVCQLLG 1165
               +   +    +  SN   +   T F++ S+ T           V++  S        G
Sbjct: 472  ETKTAYTTGSETTTASN-TGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEG 530

Query: 1166 SQ 1167
            S+
Sbjct: 531  SE 532


>gi|239513940 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1521

 Score =  134 bits (336), Expect = 8e-31
 Identities = 217/904 (24%), Positives = 370/904 (40%), Gaps = 98/904 (10%)

Query: 134 STVSSKEGVMVQTSGKSHAASDAPENLTLLAETAD----ARGRSGSSSRTNFTILPVGYS 189
           ++ +S E  +  T+G          + T  A TAD    A   +GS   T FT      +
Sbjct: 127 NSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETIT 186

Query: 190 LEIATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTASEMGTERAMGLSEEWTVH 249
              A + T+      SE+  + ++ SE      A  +++  AS MG+E     ++  T  
Sbjct: 187 PSTAGSETTTVSTAGSETTTVSTTGSETTTASTA-HSETTAASTMGSE----TTKVSTAG 241

Query: 250 SQEATTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASS----PLLDLSSS 305
           S+   ++A S +   + E  E T  +   +S     S   F  TAAS+    P +  +  
Sbjct: 242 SETTVSTAGSETTAASTEDSE-TNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMG 300

Query: 306 SESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVSKTEGFPKDSRI 365
           SE+T  + ++ G +++ VS T +  V TVF   G  T+R+ TV  G  + T      +  
Sbjct: 301 SETT--MASTIGPETTKVS-TASSEVTTVFA-AGSETIRASTV--GSETTT---VSTTGS 351

Query: 366 ATTSSSVLLSPSAVESRRNSR-VTGNPGDEEFIEPSTENEFGLTSLRWQNDSPTFGEHQL 424
            TT++S++ S ++ +S   S   T +    E    STE     T     +++ T      
Sbjct: 352 ETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDS 411

Query: 425 ASSSEVQNGSPMSQTETV--SRSVAPMRGGEITAHWLLTNSTTSADVTGSSASYPEGVNA 482
            +++    GS M+   T     + A   G EIT      + TT+A   GS  +      +
Sbjct: 412 ETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGS 471

Query: 483 SVLTQFSDSTVQSGGSHTALGDR------SYSESSSTSSSESLNSSAPRGER---SIAGI 533
              T ++  +  +  S+T L         S + ++ST  SE+   SA   E    S  G 
Sbjct: 472 ETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGS 531

Query: 534 SYGQVRGTAIEQRTSSDHTDHTYLSSTFTKG-ERALLSITDNSSSSDIVESSTSYIKISN 592
               V  T  E  T S  T     ++T T+G E   +S T   +++D  E S +    ++
Sbjct: 532 ENTTVSTTGSETTTVS--TTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGT--TAAS 587

Query: 593 SSHSEYSSFFHAQTERSNISSYDGEYAQPST---ESPVLHTSNLPSYTPTINMPNTSVVL 649
           ++ SE ++   A +E +  S+ D E    ST   E+    T++  + T +     T+ V 
Sbjct: 588 TAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVS 647

Query: 650 DTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSILPSTRASVHLLKSTSDAS 709
            TD+E    S++ S  + +S+       + +      + +    +T  S+     T   +
Sbjct: 648 TTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSI-----TGSET 702

Query: 710 TPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQSSSTPVLPRARETPVTSFQTSTMTSFMTM 769
           T  S++ S      TT+++    ++  ++  S +T       ET   S + S  TS  T 
Sbjct: 703 TKVSTTGS----ETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTT 758

Query: 770 LHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESST----- 824
              + TA   S  T     + +E+   S +   +E+TK  T +S +    TE+S      
Sbjct: 759 GSETTTASTTSSETTMASIMGSETTMASTIG--SETTKVSTASSKMTTVFTENSETTIAS 816

Query: 825 -------------EQTLPATSTNLAQMSPTFTTTILKTSQ-PLMTTPGTLSSTASLVTGP 870
                         +T+PA++      S T TTT  + S+    +T G+ ++TAS  +  
Sbjct: 817 TTASETTTVSTAGSETIPASTAG----SETTTTTSTEGSETTTASTEGSETTTASTESSE 872

Query: 871 IAVQTTAGKQLSLTHPEILVPQISTEGG----ISTERNRVIVDATTGLIPLTSVPTSAKE 926
               TT G + +           STEG      STE +     +T G   +T+V T+  E
Sbjct: 873 TTTATTIGSETTTA---------STEGSETTTTSTEGSETTTASTEG-SEITTVSTTGSE 922

Query: 927 MTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSATFAVQSSTQSPTTVSSSASV 986
            TT     +E + AS    T  S  TTV +T  +    SA     S T + TT+ S  + 
Sbjct: 923 TTTASTEGSETTTAS----TEGSELTTVSTTGSETITVSAE---GSETTTVTTMGSETTT 975

Query: 987 NSCA 990
            S A
Sbjct: 976 ASTA 979



 Score =  129 bits (323), Expect = 3e-29
 Identities = 202/902 (22%), Positives = 348/902 (38%), Gaps = 76/902 (8%)

Query: 114  ESNTEAHVENITFYQNQEDFSTVSSKEGVMVQTSGKSHAASDAPENLTLLAETADARGRS 173
            +S T +     +   ++   ++    E   V T+G         ++ T    T  +   +
Sbjct: 366  DSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTA 425

Query: 174  GSSSRTNFTILPV-GYSLEIATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTAS 232
             S++    T     G  + IA+   S++   ++E     + ++   E   A+ T S T +
Sbjct: 426  VSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTT 485

Query: 233  EMGTERAMGLSEEWTVHSQEATTSAWSPSFLPALEMG-ELTTPSRKRNSSGPDLSWLHFY 291
               T   +  +  +T+ S   T S            G E+TT S + + +    +     
Sbjct: 486  ASNT--GLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSET 543

Query: 292  RTAASSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLG 351
             T +++ L   ++S+E +E    ST    ++   T+        T G   T    TVS  
Sbjct: 544  TTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETT----TVSTA 599

Query: 352  PVSKTEGFPKDSRIATTSSSVLLSPSAVESRRNSRVT--GNPGDEEFIEPSTENEFGLTS 409
                T     DS   TTS+S   S +   S  +S  T     G E     +T++E  + S
Sbjct: 600  DSENTTASTADSE--TTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVS 657

Query: 410  LRWQNDSPTFGEHQLASSSEVQNGSPMSQT---ETVSRSVAPMRGGEITAHWLLTNSTTS 466
                    T G  +  +S+E    + +S T    TVS   +      IT       STT 
Sbjct: 658  --------TTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTG 709

Query: 467  ADVTGSSASYPEGVNASVLTQFSDSTVQSGGSHTALGDRSYSE--SSSTSSSESLNSSAP 524
            ++ T +S    E   AS+ T    +T  + GS T       SE  S+ST+ SE+  +S  
Sbjct: 710  SETTTTSTEGSEITTASI-TGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTT 768

Query: 525  RGERSIAGISYGQVR-GTAIEQRTSSDHTDHTYLSSTFTKGERALLSITDNSSSSDIVES 583
              E ++A I   +    + I   T+   T  + +++ FT+     ++ T  S ++ +  +
Sbjct: 769  SSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTA 828

Query: 584  STSYIKISNSSHSEYSSFFHAQTERSNISSYDGEYAQPSTESPVLHTSNLPSYTPTINMP 643
             +  I  S +     ++     +E +  S+   E    STES    T+       TI   
Sbjct: 829  GSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTAT------TIGSE 882

Query: 644  NTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSI------LPSTRA 697
             T+    T+    + +S+  S ++++S+ G  +   S + S    +S         ST  
Sbjct: 883  TTTA--STEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEG 940

Query: 698  SVHLLKSTSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQSSSTPVLPRARETPVTS 757
            S     ST+ + T   S+      ++TT  S   + S      S +T V     ET   S
Sbjct: 941  SELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAG---SETTTVSTAGSETTTAS 997

Query: 758  FQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPT---ESTKAVTTNSP 814
             + S  T+      SS  ++  + ST   E  IT ++     ++ T   E+T   TT S 
Sbjct: 998  IEGSETTTV-----SSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSE 1052

Query: 815  LPPSLTESSTEQTLPATSTNLAQMSPT-FTTTILKTSQPLMTTPGTLSSTASLVTGPIAV 873
               + TE S   T+  T +     S     TT + TS    TT  T  S  + V    + 
Sbjct: 1053 TTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSK 1112

Query: 874  QTTAGKQLSLTHPEILVPQISTEGG----ISTERNRVIVDATTGLIPLTSVPTSAKEMTT 929
             TTA                STEG     +ST  +     +TTG   +T+V T+  E TT
Sbjct: 1113 TTTA----------------STEGSEATTVSTTSSETTTASTTG-SEMTTVFTTVSETTT 1155

Query: 930  --KLGVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSATFAVQSSTQSPTTVSSSASVN 987
               +G  A  S A+ S  T+ S + +  +TA     ++ T +   S  +  + S S +  
Sbjct: 1156 VSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNT 1215

Query: 988  SC 989
            +C
Sbjct: 1216 AC 1217



 Score =  118 bits (296), Expect = 3e-26
 Identities = 200/902 (22%), Positives = 348/902 (38%), Gaps = 74/902 (8%)

Query: 134  STVSSKEGVMVQTSG-KSHAASDAPENLTLLAETADARGRSGSSSRTNFTILPVGYSLEI 192
            ST+ S E  M  T G ++   S A   +T +        R+ +      T+   G     
Sbjct: 297  STMGS-ETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTT 355

Query: 193  ATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTASEMGTERAMGLSEEWTVH--S 250
            A+ + S++   ++      ++S+E  E   A    S   SE  T    G SE  TV    
Sbjct: 356  ASIMGSETSTDSTTGSETTTASTEGSETTTA----STEGSEATTVSTTG-SETTTVSITD 410

Query: 251  QEATTSAWSPSFLPAL------------EMGELT---TPSRKRNSSGPDLSWLHFYRTAA 295
             E TT+    S + A+            E  E+T   T   +  ++  + S      TA 
Sbjct: 411  SETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAG 470

Query: 296  SSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVSK 355
            S      ++ SE+T   N  TGL++++V  T      T  T+G   T  S T S      
Sbjct: 471  SETKTAYTTGSETTTASN--TGLETTTVF-TIGSDTTTASTEGSETTAVSATGSEMTTVS 527

Query: 356  TEGFPKDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQND 415
            TEG    +   T S +  +S + +E+   S         E  E +T +  G  +     +
Sbjct: 528  TEGSENTTVSTTGSETTTVSTTGLETTTTST--------EGSEMTTVSTTGAETTTDSTE 579

Query: 416  SPTFGEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADVTGSSAS 475
                     A S      +  S+  T S + +       T     T STTS++ T +S  
Sbjct: 580  GSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTE 639

Query: 476  YPEGVNASVLTQFSDSTVQSGGSHTALGDRSYSESSSTSSSESLNSSAPRGER----SIA 531
              E    S  T    + V + GS   +     SE+++ S++ S  + +  G      SI 
Sbjct: 640  GSETTTVST-TDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSIT 698

Query: 532  GISYGQVRGTAIEQRTSSDHTDHTYLSS--------TFTKGERALLSITDNS--SSSDIV 581
            G    +V  T  E  T+S        +S          T+G     + T+ S  +S+   
Sbjct: 699  GSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTT 758

Query: 582  ESSTSYIKISNSSHSEYSSFFHAQTERSNISSYDGEYAQPSTESPVLHTSNLPSYTPTIN 641
             S T+    ++S  +  S      T  S I S   + +  S++   + T N  +   +  
Sbjct: 759  GSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTT 818

Query: 642  MPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSILPS-TRASVH 700
               T+ V    +E +  S++ S +++++S+ G      S   S    +S   S T  +  
Sbjct: 819  ASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATT 878

Query: 701  LLKSTSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQ--SSSTPVLPRARETPVTSF 758
            +   T+ AST  S + +       T+T++      TT+    S +T       ET   S 
Sbjct: 879  IGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAST 938

Query: 759  QTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPS 818
            + S +T+  T    S+T  + ++ +         S++ +  +  +E+T   T  S    +
Sbjct: 939  EGSELTTVSTT--GSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTA 996

Query: 819  LTESSTEQTLPATSTNLAQMSPTFTTTILKTSQPLMTTPGTLSSTASLVTGPIAVQTTAG 878
              E S   T+ +T +    +S T T T + +++   TT  T+++  S  T   AV TT  
Sbjct: 997  SIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETT--TVTTAGSETT---AVYTTGS 1051

Query: 879  KQLSLTHPEILVPQISTEGGISTERNRVIVDATTGLIP---LTSVPTSAKEMTTKLGVTA 935
            +  + +        +ST G  +T  +   ++ TT        T+  T+  E TT     +
Sbjct: 1052 ETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGS 1111

Query: 936  EYSPASRSLGTSPSPQTTVVSTAEDLAPKSAT-------FAVQSSTQSPTTVSSSASVNS 988
            + + AS    T  S  TTV +T+ +    S T       F   S T + +T+ S A+ +S
Sbjct: 1112 KTTTAS----TEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSS 1167

Query: 989  CA 990
             A
Sbjct: 1168 AA 1169



 Score =  109 bits (273), Expect = 2e-23
 Identities = 205/949 (21%), Positives = 368/949 (38%), Gaps = 111/949 (11%)

Query: 124  ITFYQNQEDFSTVSSKEGVMVQTSGKSHAASDAPENLTLLAETADARGRSGSSSRTNFTI 183
            IT     +  +T +S EG   +T+  + A S+     T  +ET  A   +G  + T FTI
Sbjct: 443  ITIASTSDSETTTASTEGS--ETTTVTTAGSETKTAYTTGSETTTA-SNTGLETTTVFTI 499

Query: 184  LPVGYSLEIATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTASEMGTERAMGLS 243
               G     A+   S++  +++    + + S+E  E      T S T SE  T    GL 
Sbjct: 500  ---GSDTTTASTEGSETTAVSATGSEMTTVSTEGSENT----TVSTTGSETTTVSTTGLE 552

Query: 244  EEWTVH--SQEATTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASSPLLD 301
               T    S+  T S            G  TT +    S    +S      T AS+   +
Sbjct: 553  TTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSE 612

Query: 302  LSSSSES-TEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVSKTEGFP 360
             +S+S + +E    ST    ++ + T+     TV T     T+ S T S   ++ TEG  
Sbjct: 613  TTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSE 672

Query: 361  ----------------------------KDSRIATTSSSVLLSPSAVESRRNSRVTGNPG 392
                                        + ++++TT S    + +       + +TG+  
Sbjct: 673  TTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSET 732

Query: 393  DEEFIEPSTENEFGLTSLRWQNDSPTFGEHQLAS--SSEVQNGSPMSQTETVSRSVAPMR 450
                 E S             + S T  E   AS  SSE    S M    T++ ++    
Sbjct: 733  TTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSET 792

Query: 451  GGEITAHWLLTN-----------STTSADVTGSSASYPEGVNASVLTQFSDSTVQSGGSH 499
                TA   +T            STT+++ T  S +  E + AS     + +T  + GS 
Sbjct: 793  TKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSE 852

Query: 500  TALGDRSYSESS--STSSSESLNSSAPRGERSIAGISYGQVRGTAIE-QRTSSDHTDHTY 556
            T       SE++  ST SSE+  ++    E + A     +   T+ E   T++  T+ + 
Sbjct: 853  TTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSE 912

Query: 557  LSSTFTKGERALLSITDNSSSSDIVESSTSYIKISNSSHSEYSSFFHAQTERSNISSYDG 616
            +++  T G     + T+ S ++      +    +S +  SE  +     +E + +++   
Sbjct: 913  ITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTG-SETITVSAEGSETTTVTTMGS 971

Query: 617  EYAQPST---ESPVLHTSNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSG 673
            E    ST   E+  + T+   + T +I    T+ V  T +E  + S++ + ++ +S+   
Sbjct: 972  ETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGS 1031

Query: 674  PPLPLPSV-SQSHHLFSS----ILPSTRASVHLLKSTSDASTPWSSSPSPLPVSLTTS-- 726
                + +  S++  ++++       ST  S     ST+ + T  +S+      +++TS  
Sbjct: 1032 ETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGS 1091

Query: 727  --TSAPLSVSQTTLPQ-------------SSSTPVLPRARETPVTSFQTSTMTSFMTMLH 771
              T+A  + S+TT                S +T V   + ET   S   S MT+  T + 
Sbjct: 1092 GTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVS 1151

Query: 772  SSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESSTEQTLPAT 831
             + T      ST   E   + +      +  TE ++  TT S      T +ST  +   T
Sbjct: 1152 ETTTV-----STIGSEATTSSAAGSEATTTSTEGSE-TTTASTAGSETTTASTAGSETTT 1205

Query: 832  STNLAQMSPTFTTTILKTSQPLMTTPGTLSSTASLVTGPIAVQTTAGKQ---LSLTHPEI 888
            ++     + T  TT  +TS P  ++ G+ ++TA ++     + +TA  +    SLT  E 
Sbjct: 1206 ASTSGSETNTACTTGSETSTP--SSAGSETNTAFIIGSESTIASTASLEPTATSLTGSET 1263

Query: 889  LVPQISTEGGIS-----TERNRVIVDAT-TGLIPLTSVPTSAKEMT-TKLGVTAEYSPAS 941
                I+  G  +     +    V+  AT   + P+T+ P S    T T+L        AS
Sbjct: 1264 TTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRL-------TAS 1316

Query: 942  RSLGTSPSPQTTVVSTAEDLAPKSA--TFAVQSSTQSPTTVSSSASVNS 988
             S+  +P    T  S A    P     T  + +ST   ++ +S+  V +
Sbjct: 1317 SSVTMAPGMDFT-ASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRT 1364



 Score =  105 bits (261), Expect = 4e-22
 Identities = 191/857 (22%), Positives = 342/857 (39%), Gaps = 147/857 (17%)

Query: 230 TASEMGTERAMGLSEEWTVHSQEATTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLH 289
           TAS  G+E    L     + + E TT++ + S        E TTPS       P  S   
Sbjct: 17  TASTTGSETTTIL-----IKASETTTASTAGS--------ETTTPS-------PTGSQTT 56

Query: 290 FYRTAASSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVS 349
               + S      ++ SE+T   +  +G  ++S++ ++T    TV T G   T  S+T +
Sbjct: 57  IVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSET----TVSTAGSETTTVSITGT 112

Query: 350 LGPVSKTEGFPKDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTS 409
              +    G    +   T+S + + S +  E+   S V    G E     + ++E    S
Sbjct: 113 ETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTV----GSETTTAYTADSETTAAS 168

Query: 410 LRWQNDSPTFGEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADV 469
                 +  F     A S  +   +  S+T TVS +     G E T     T STT ++ 
Sbjct: 169 TTGSEMTTVF----TAGSETITPSTAGSETTTVSTA-----GSETT-----TVSTTGSET 214

Query: 470 TGSSASYPEGVNAS--------VLTQFSDSTVQSGGS------------HTALGDRSYSE 509
           T +S ++ E   AS        V T  S++TV + GS            +TA  + S + 
Sbjct: 215 TTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTT 274

Query: 510 SSSTSSSESLNSSAPRGERSIAGISYGQ-VRGTAIEQRTSSDHTDHTYLSSTFTKGERAL 568
           ++ST+  E+  +S    E ++A     +    + I   T+   T  + +++ F  G   +
Sbjct: 275 TASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETI 334

Query: 569 LSITDNSSSSDIVESSTSYIKISNSSHSEYSSFFHAQTERSNISSYDGEYAQPSTE-SPV 627
            + T  S ++  V ++ S    ++   SE S+     +E +  S+   E    STE S  
Sbjct: 335 RASTVGSETT-TVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEA 393

Query: 628 LHTSNLPSYTPTINMPNT---------------------SVVLDTDAEFVSDSSSSSSSS 666
              S   S T T+++ ++                     +    T+   ++ +S+S S +
Sbjct: 394 TTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSET 453

Query: 667 SSSSSSGPPLPLPSV--SQSHHLFSSILPSTRASVHLLKST------SDASTPWSSSPSP 718
           +++S+ G      +   S++   +++   +T AS   L++T      SD +T  +     
Sbjct: 454 TTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSET 513

Query: 719 LPVSLTTSTSAPLSV---SQTTLPQ--SSSTPVLPRARETPVTSFQTSTMTSFMT----- 768
             VS T S    +S      TT+    S +T V     ET  TS + S MT+  T     
Sbjct: 514 TAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAET 573

Query: 769 -------------MLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPL 815
                            S+T  + +  + +      +S++ S  +  +E+T A TT+S  
Sbjct: 574 TTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSET 633

Query: 816 PPSLTESSTEQTLPATSTNLAQMSPT------------FTTTILKT-SQPLMTTPGTLSS 862
             + TE S   T+  T +    +S T             TTT+  T S+  ++T G+ ++
Sbjct: 634 TTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTT 693

Query: 863 TASLVTGPIAVQTTAGKQLSLTH---PEILVPQI--------STEGG----ISTERNRVI 907
           T S+        +T G + + T     EI    I        STEG      STE +   
Sbjct: 694 TVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETT 753

Query: 908 VDATTGLIPLTSVPTSAKEMTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSAT 967
             +TTG    T+  TS++  TT   +    +  + ++G+  +  +T  S    +  +++ 
Sbjct: 754 SASTTGSETTTASTTSSE--TTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSE 811

Query: 968 FAVQSSTQSPTTVSSSA 984
             + S+T S TT  S+A
Sbjct: 812 TTIASTTASETTTVSTA 828



 Score = 93.6 bits (231), Expect = 1e-18
 Identities = 138/603 (22%), Positives = 237/603 (39%), Gaps = 69/603 (11%)

Query: 445 SVAPMRGGEITAHWLLTNSTTSADVTGSSASYPE---------GVNASVLTQFS-----D 490
           + A   G E T   +  + TT+A   GS  + P           ++ S +T  S     +
Sbjct: 16  TTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSEN 75

Query: 491 STVQSGGSHTALGDRSYSESS-STSSSESLNSSAPRGERSIAGISYGQVRGTAIEQRTSS 549
           +TV S GS T     + SE++ ST+ SE+          SI G     V     E  T+S
Sbjct: 76  TTVSSAGSGTTTASMAGSETTVSTAGSETTTV-------SITGTETTMVSAMGSETTTNS 128

Query: 550 DHTDHTYLSSTFTKGERALLSITDNSSSSDIVESSTSYIKISNSSHSEYSSFFHAQTERS 609
             +  T ++ST       + ++   ++++   +S T+    ++++ SE ++ F A +E  
Sbjct: 129 TTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETT---AASTTGSEMTTVFTAGSETI 185

Query: 610 NISSYDGEYAQPST---ESPVLHTSNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSS 666
             S+   E    ST   E+  + T+   + T +     T+      +E    S++ S ++
Sbjct: 186 TPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETT 245

Query: 667 SSSSSSGPPLPLPSVSQSHHLFSSILPSTRASVHLLKSTSDASTPWSSSPSPLPVSLTTS 726
            S++ S         S+++  F+    +T AS    ++T+ AST  S       +   T+
Sbjct: 246 VSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTA-ASTTGSEPTMASTMGSETT 304

Query: 727 TSAPLSVSQTTLPQSSS--TPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADL-----K 779
            ++ +    T +  +SS  T V     ET   S   S  T+  T    + TA +      
Sbjct: 305 MASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETS 364

Query: 780 SQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESSTEQTLPATSTNLAQMS 839
           + ST   E     ++     +  TE ++A T ++    + T S T+     T T  ++M+
Sbjct: 365 TDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMT 424

Query: 840 PTFTT--------------TILKTSQPLMTTPGTLSSTASLVT----GPIAVQTTAGKQL 881
              TT              TI  TS    TT  T  S  + VT          TT  +  
Sbjct: 425 AVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETT 484

Query: 882 SLTHPEILVPQISTEGG----ISTERNRVIVDATTGLIPLTSVPTSAKEMTTKLGVTAEY 937
           + ++  +    + T G      STE +     + TG   +T+V T   E TT     +E 
Sbjct: 485 TASNTGLETTTVFTIGSDTTTASTEGSETTAVSATG-SEMTTVSTEGSENTTVSTTGSET 543

Query: 938 SPAS------RSLGTSPSPQTTV----VSTAEDLAPKSATFAVQSSTQSPTTVSSSASVN 987
           +  S       +  T  S  TTV      T  D    S T A  ++    TTVS++ S N
Sbjct: 544 TTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSEN 603

Query: 988 SCA 990
           + A
Sbjct: 604 TTA 606



 Score = 75.1 bits (183), Expect = 4e-13
 Identities = 146/624 (23%), Positives = 255/624 (40%), Gaps = 74/624 (11%)

Query: 116  NTEAHVENITFYQNQEDFSTVSS--KEGVMVQTSGK---SHAASDAPENLTLLAETADAR 170
            N+E  + + T      + +TVS+   E +   T+G    +  +++  E  T   E ++  
Sbjct: 809  NSETTIASTT----ASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETT 864

Query: 171  GRSGSSSRTNFTILPVGYSLEIATALTSQSGNLASESLHLPSSSSEFDE--RIAAFQTKS 228
              S  SS T  T   +G     A+   S++   ++E     ++S+E  E   ++   +++
Sbjct: 865  TASTESSETT-TATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSET 923

Query: 229  GTASEMGTERAMGLSEEW------TVHSQEATTSAWSPSFLPALEMGELTTPSRKRNSSG 282
             TAS  G+E     +E        T  S+  T SA          MG  TT +    S  
Sbjct: 924  TTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSET 983

Query: 283  PDLSWLHFYRTAASSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRT 342
              +S      TA S         SE+T    +STG ++++VS T T    T  T+G   T
Sbjct: 984  TTVS------TAGSETTTASIEGSETTTV--SSTGSETTTVSTTGTETTITS-TEGSETT 1034

Query: 343  LRSLTVSLGPVSKTEGFPKDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTE 402
                TV+      T  +   S   TTS+      + V +  +   T +  D E    ST 
Sbjct: 1035 ----TVTTAGSETTAVYTTGSETTTTSTEGS-ETTTVSTTGSETTTASTADLETTTVSTS 1089

Query: 403  NEFGLTSLRWQNDSPTF---GEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWL 459
                 T+    +++ T    G     +S+E    + +S T + + + A   G E+T  + 
Sbjct: 1090 GSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSET-TTASTTGSEMTTVFT 1148

Query: 460  LTNSTTS-----ADVTGSSASYPEGVNASVLTQFSDSTVQS-GGSHTALGDRSYSESSST 513
              + TT+     ++ T SSA+  E    S  T+ S++T  S  GS T     + SE+++ 
Sbjct: 1149 TVSETTTVSTIGSEATTSSAAGSEATTTS--TEGSETTTASTAGSETTTASTAGSETTTA 1206

Query: 514  SSSES-LNSSAPRGERSIAGISYGQVRGTAI---EQRTSSDHTDHTYLSSTFTKGERALL 569
            S+S S  N++   G  +    S G    TA     + T +        +++ T  E   +
Sbjct: 1207 STSGSETNTACTTGSETSTPSSAGSETNTAFIIGSESTIASTASLEPTATSLTGSETTTV 1266

Query: 570  SIT-DNSSSSDIVESSTSYI----------KISNSSHSEYSSFFHAQTERSNIS-----S 613
            SIT   ++++    SST+++           I+N+  S   +     T  S+++      
Sbjct: 1267 SITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMD 1326

Query: 614  YDGEYAQPSTESPVLHTSNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSSSSSS--S 671
            +    A  +    VL+TS L   T T+   +T     T A  V  ++ S+   +SS+   
Sbjct: 1327 FTASAASHTVPGIVLNTSGLG--TSTMGASST-----TSAHGVRTTTGSTREPTSSTFQE 1379

Query: 672  SGP-PLPLPSVSQSHHLFSSILPS 694
            +GP  +   +VS SH   + I PS
Sbjct: 1380 TGPVSMGTNTVSMSHTPTNVIKPS 1403



 Score = 61.2 bits (147), Expect = 6e-09
 Identities = 106/542 (19%), Positives = 202/542 (37%), Gaps = 41/542 (7%)

Query: 644  NTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSILPSTRASVHLLK 703
            NT+    T +E  +     +S ++++S++G     PS + S    ++I+  + + +    
Sbjct: 14   NTTTASTTGSE-TTTILIKASETTTASTAGSETTTPSPTGSQ---TTIVSISGSEITTTS 69

Query: 704  STSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQSSSTPVLPRARETPVTSFQTSTM 763
            +    +T  SS+ S      TT++ A    + +T    ++T  +     T V++  + T 
Sbjct: 70   TAGSENTTVSSAGS----GTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETT 125

Query: 764  TSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESS 823
            T+  T   ++ T+   S++T         S++ +  +  +E+T A TT S +    T  S
Sbjct: 126  TNSTTSSETTVTSTAGSETTTVS---TVGSETTTAYTADSETTAASTTGSEMTTVFTAGS 182

Query: 824  TEQTLPATSTNLAQMSPTFTTTILKTSQPLMTTPGTLSSTASLVTGPIAVQTTAGKQLSL 883
             E   P+T+      S T T +   +    ++T G+ ++TAS         +T G + + 
Sbjct: 183  -ETITPSTAG-----SETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTK 236

Query: 884  THPEILVPQISTEGGIST-------ERNRVIV-DATTGLIPLTSVPTSAKEMTTKLGVTA 935
                     +ST G  +T       E N     D+ T     T   T+A   T      A
Sbjct: 237  VSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMA 296

Query: 936  EYSPASRSLGTSPSPQTTVVSTAED-----LAPKSATFAVQSSTQSPTTVSSSASVNSCA 990
                +  ++ ++  P+TT VSTA        A  S T    +     TTVS++ S  + A
Sbjct: 297  STMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTA 356

Query: 991  VNPCLHNGECVADNTSRGYHCRCPPSWQGDDCSVDVNE-----CLSNPCPSTAMCNNTQG 1045
                +   E   D+T+         S +G + +    E      +S     T   + T  
Sbjct: 357  ---SIMGSETSTDSTTGSE--TTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDS 411

Query: 1046 SFICKCPVGYQLEKGICNLVRTFVTEFKLKRTFLNTTVEKHSDLQEVENEITKTLNMCFS 1105
                 C  G ++      +  T     +     + +T +  +     E   T T+    S
Sbjct: 412  ETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGS 471

Query: 1106 ALPSYIRSTVHASRESNAVVISLQTTFSLASNVTLFDLADRMQKCVNSCKSSAEVCQLLG 1165
               +   +    +  SN   +   T F++ S+ T           V++  S        G
Sbjct: 472  ETKTAYTTGSETTTASN-TGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEG 530

Query: 1166 SQ 1167
            S+
Sbjct: 531  SE 532


>gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo
           sapiens]
          Length = 1521

 Score =  132 bits (333), Expect = 2e-30
 Identities = 216/904 (23%), Positives = 369/904 (40%), Gaps = 98/904 (10%)

Query: 134 STVSSKEGVMVQTSGKSHAASDAPENLTLLAETAD----ARGRSGSSSRTNFTILPVGYS 189
           ++ +S E  +  T+G          + T  A TAD    A   +GS   T FT      +
Sbjct: 127 NSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETIT 186

Query: 190 LEIATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTASEMGTERAMGLSEEWTVH 249
              A + T+      SE+  + ++ SE      A  +++  AS MG+E     ++  T  
Sbjct: 187 PSTAGSETTTVSTAGSETTTVSTTGSETTTASTA-HSETTAASTMGSE----TTKVSTAG 241

Query: 250 SQEATTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASS----PLLDLSSS 305
           S+   ++A S +   + E  E T  +   +S     S   F  TAAS+    P +  +  
Sbjct: 242 SETTVSTAGSETTAASTEDSE-TNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMG 300

Query: 306 SESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVSKTEGFPKDSRI 365
           SE+T  + ++ G +++ VS T +  V TVF   G  T+R+ TV  G  + T      +  
Sbjct: 301 SETT--MASTIGPETTKVS-TASSEVTTVFA-AGSETIRASTV--GSETTT---VSTTGS 351

Query: 366 ATTSSSVLLSPSAVESRRNSR-VTGNPGDEEFIEPSTENEFGLTSLRWQNDSPTFGEHQL 424
            TT++S++ S ++ +S   S   T +    E    STE     T     +++ T      
Sbjct: 352 ETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDS 411

Query: 425 ASSSEVQNGSPMSQTETV--SRSVAPMRGGEITAHWLLTNSTTSADVTGSSASYPEGVNA 482
            +++    GS M+   T     + A   G EIT      + TT+A   GS  +      +
Sbjct: 412 ETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGS 471

Query: 483 SVLTQFSDSTVQSGGSHTALGDR------SYSESSSTSSSESLNSSAPRGER---SIAGI 533
              T ++  +  +  S+T L         S + ++ST  SE+   SA   E    S  G 
Sbjct: 472 ETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGS 531

Query: 534 SYGQVRGTAIEQRTSSDHTDHTYLSSTFTKG-ERALLSITDNSSSSDIVESSTSYIKISN 592
               V  T  E  T S  T     ++T T+G E   +S T   +++D  E S +    ++
Sbjct: 532 ENTTVSTTGSETTTVS--TTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGT--TAAS 587

Query: 593 SSHSEYSSFFHAQTERSNISSYDGEYAQPST---ESPVLHTSNLPSYTPTINMPNTSVVL 649
           ++ SE ++   A +E +  S+ D E    ST   E+    T++  + T +     T+ V 
Sbjct: 588 TAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVS 647

Query: 650 DTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSILPSTRASVHLLKSTSDAS 709
            TD+E    S++ S  + +S+       + +      + +    +T  S+     T   +
Sbjct: 648 TTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSI-----TGSET 702

Query: 710 TPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQSSSTPVLPRARETPVTSFQTSTMTSFMTM 769
           T  S++ S   ++ T  +     ++  ++  S +T       ET   S + S  TS  T 
Sbjct: 703 TKVSTTGSETTITSTEGS----EITTASITGSETTTASTEGSETTTASTEGSETTSASTT 758

Query: 770 LHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESST----- 824
              + TA   S  T     + +E+   S +   +E+TK  T +S +    TE+S      
Sbjct: 759 GSETTTASTTSSETTMASIMGSETTMASTIG--SETTKVSTASSKMTTVFTENSETTIAS 816

Query: 825 -------------EQTLPATSTNLAQMSPTFTTTILKTSQ-PLMTTPGTLSSTASLVTGP 870
                         +T+PA++      S T TTT  + S+    +T G+ ++TAS  +  
Sbjct: 817 TTASETTTVSTAGSETIPASTAG----SETTTTTSTEGSETTTASTEGSETTTASTESSE 872

Query: 871 IAVQTTAGKQLSLTHPEILVPQISTEGG----ISTERNRVIVDATTGLIPLTSVPTSAKE 926
               TT G + +           STEG      STE +     +T G   +T+V T+  E
Sbjct: 873 TTTATTIGSETTTA---------STEGSETTTTSTEGSETTTASTEG-SEITTVSTTGSE 922

Query: 927 MTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSATFAVQSSTQSPTTVSSSASV 986
            TT     +E + AS    T  S  TTV +T  +    SA     S T + TT+ S  + 
Sbjct: 923 TTTASTEGSETTTAS----TEGSELTTVSTTGSETITVSAE---GSETTTVTTMGSETTT 975

Query: 987 NSCA 990
            S A
Sbjct: 976 ASTA 979



 Score =  128 bits (321), Expect = 4e-29
 Identities = 202/902 (22%), Positives = 348/902 (38%), Gaps = 76/902 (8%)

Query: 114  ESNTEAHVENITFYQNQEDFSTVSSKEGVMVQTSGKSHAASDAPENLTLLAETADARGRS 173
            +S T +     +   ++   ++    E   V T+G         ++ T    T  +   +
Sbjct: 366  DSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTA 425

Query: 174  GSSSRTNFTILPV-GYSLEIATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTAS 232
             S++    T     G  + IA+   S++   ++E     + ++   E   A+ T S T +
Sbjct: 426  VSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTT 485

Query: 233  EMGTERAMGLSEEWTVHSQEATTSAWSPSFLPALEMG-ELTTPSRKRNSSGPDLSWLHFY 291
               T   +  +  +T+ S   T S            G E+TT S + + +    +     
Sbjct: 486  ASNT--GLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSET 543

Query: 292  RTAASSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLG 351
             T +++ L   ++S+E +E    ST    ++   T+        T G   T    TVS  
Sbjct: 544  TTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETT----TVSTA 599

Query: 352  PVSKTEGFPKDSRIATTSSSVLLSPSAVESRRNSRVT--GNPGDEEFIEPSTENEFGLTS 409
                T     DS   TTS+S   S +   S  +S  T     G E     +T++E  + S
Sbjct: 600  DSENTTASTADSE--TTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVS 657

Query: 410  LRWQNDSPTFGEHQLASSSEVQNGSPMSQT---ETVSRSVAPMRGGEITAHWLLTNSTTS 466
                    T G  +  +S+E    + +S T    TVS   +      IT       STT 
Sbjct: 658  --------TTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTG 709

Query: 467  ADVTGSSASYPEGVNASVLTQFSDSTVQSGGSHTALGDRSYSE--SSSTSSSESLNSSAP 524
            ++ T +S    E   AS+ T    +T  + GS T       SE  S+ST+ SE+  +S  
Sbjct: 710  SETTITSTEGSEITTASI-TGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTT 768

Query: 525  RGERSIAGISYGQVR-GTAIEQRTSSDHTDHTYLSSTFTKGERALLSITDNSSSSDIVES 583
              E ++A I   +    + I   T+   T  + +++ FT+     ++ T  S ++ +  +
Sbjct: 769  SSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTA 828

Query: 584  STSYIKISNSSHSEYSSFFHAQTERSNISSYDGEYAQPSTESPVLHTSNLPSYTPTINMP 643
             +  I  S +     ++     +E +  S+   E    STES    T+       TI   
Sbjct: 829  GSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTAT------TIGSE 882

Query: 644  NTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSI------LPSTRA 697
             T+    T+    + +S+  S ++++S+ G  +   S + S    +S         ST  
Sbjct: 883  TTTA--STEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEG 940

Query: 698  SVHLLKSTSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQSSSTPVLPRARETPVTS 757
            S     ST+ + T   S+      ++TT  S   + S      S +T V     ET   S
Sbjct: 941  SELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAG---SETTTVSTAGSETTTAS 997

Query: 758  FQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPT---ESTKAVTTNSP 814
             + S  T+      SS  ++  + ST   E  IT ++     ++ T   E+T   TT S 
Sbjct: 998  IEGSETTTV-----SSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSE 1052

Query: 815  LPPSLTESSTEQTLPATSTNLAQMSPT-FTTTILKTSQPLMTTPGTLSSTASLVTGPIAV 873
               + TE S   T+  T +     S     TT + TS    TT  T  S  + V    + 
Sbjct: 1053 TTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSK 1112

Query: 874  QTTAGKQLSLTHPEILVPQISTEGG----ISTERNRVIVDATTGLIPLTSVPTSAKEMTT 929
             TTA                STEG     +ST  +     +TTG   +T+V T+  E TT
Sbjct: 1113 TTTA----------------STEGSEATTVSTTSSETTTASTTG-SEMTTVFTTVSETTT 1155

Query: 930  --KLGVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSATFAVQSSTQSPTTVSSSASVN 987
               +G  A  S A+ S  T+ S + +  +TA     ++ T +   S  +  + S S +  
Sbjct: 1156 VSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNT 1215

Query: 988  SC 989
            +C
Sbjct: 1216 AC 1217



 Score =  118 bits (296), Expect = 3e-26
 Identities = 202/902 (22%), Positives = 352/902 (39%), Gaps = 74/902 (8%)

Query: 134  STVSSKEGVMVQTSG-KSHAASDAPENLTLLAETADARGRSGSSSRTNFTILPVGYSLEI 192
            ST+ S E  M  T G ++   S A   +T +        R+ +      T+   G     
Sbjct: 297  STMGS-ETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTT 355

Query: 193  ATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTASEMGTERAMGLSEEWTVH--S 250
            A+ + S++   ++      ++S+E  E   A    S   SE  T    G SE  TV    
Sbjct: 356  ASIMGSETSTDSTTGSETTTASTEGSETTTA----STEGSEATTVSTTG-SETTTVSITD 410

Query: 251  QEATTSAWSPSFLPAL------------EMGELT---TPSRKRNSSGPDLSWLHFYRTAA 295
             E TT+    S + A+            E  E+T   T   +  ++  + S      TA 
Sbjct: 411  SETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAG 470

Query: 296  SSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVSK 355
            S      ++ SE+T   N  TGL++++V  T      T  T+G   T  S T S      
Sbjct: 471  SETKTAYTTGSETTTASN--TGLETTTVF-TIGSDTTTASTEGSETTAVSATGSEMTTVS 527

Query: 356  TEGFPKDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQND 415
            TEG    +   T S +  +S + +E+   S         E  E +T +  G  +     +
Sbjct: 528  TEGSENTTVSTTGSETTTVSTTGLETTTTST--------EGSEMTTVSTTGAETTTDSTE 579

Query: 416  SPTFGEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADVTGSSAS 475
                     A S      +  S+  T S + +       T     T STTS++ T +S  
Sbjct: 580  GSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTE 639

Query: 476  YPEGVNASVLTQFSDSTVQSGGSHTALGDRSYSESSSTSSSESLNSSAPRGER----SIA 531
              E    S  T    + V + GS   +     SE+++ S++ S  + +  G      SI 
Sbjct: 640  GSETTTVST-TDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSIT 698

Query: 532  GISYGQVRGTAIEQR-TSSDHTDHTYLSST-------FTKGERALLSITDNS--SSSDIV 581
            G    +V  T  E   TS++ ++ T  S T        T+G     + T+ S  +S+   
Sbjct: 699  GSETTKVSTTGSETTITSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTT 758

Query: 582  ESSTSYIKISNSSHSEYSSFFHAQTERSNISSYDGEYAQPSTESPVLHTSNLPSYTPTIN 641
             S T+    ++S  +  S      T  S I S   + +  S++   + T N  +   +  
Sbjct: 759  GSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTT 818

Query: 642  MPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSILPS-TRASVH 700
               T+ V    +E +  S++ S +++++S+ G      S   S    +S   S T  +  
Sbjct: 819  ASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATT 878

Query: 701  LLKSTSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQ--SSSTPVLPRARETPVTSF 758
            +   T+ AST  S + +       T+T++      TT+    S +T       ET   S 
Sbjct: 879  IGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAST 938

Query: 759  QTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPS 818
            + S +T+  T    S+T  + ++ +         S++ +  +  +E+T   T  S    +
Sbjct: 939  EGSELTTVSTT--GSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTA 996

Query: 819  LTESSTEQTLPATSTNLAQMSPTFTTTILKTSQPLMTTPGTLSSTASLVTGPIAVQTTAG 878
              E S   T+ +T +    +S T T T + +++   TT  T+++  S  T   AV TT  
Sbjct: 997  SIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETT--TVTTAGSETT---AVYTTGS 1051

Query: 879  KQLSLTHPEILVPQISTEGGISTERNRVIVDATTGLIP---LTSVPTSAKEMTTKLGVTA 935
            +  + +        +ST G  +T  +   ++ TT        T+  T+  E TT     +
Sbjct: 1052 ETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGS 1111

Query: 936  EYSPASRSLGTSPSPQTTVVSTAEDLAPKSAT-------FAVQSSTQSPTTVSSSASVNS 988
            + + AS    T  S  TTV +T+ +    S T       F   S T + +T+ S A+ +S
Sbjct: 1112 KTTTAS----TEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSS 1167

Query: 989  CA 990
             A
Sbjct: 1168 AA 1169



 Score =  111 bits (278), Expect = 4e-24
 Identities = 207/948 (21%), Positives = 374/948 (39%), Gaps = 109/948 (11%)

Query: 124  ITFYQNQEDFSTVSSKEGVMVQTSGKSHAASDAPENLTLLAETADARGRSGSSSRTNFTI 183
            IT     +  +T +S EG   +T+  + A S+     T  +ET  A   +G  + T FTI
Sbjct: 443  ITIASTSDSETTTASTEGS--ETTTVTTAGSETKTAYTTGSETTTA-SNTGLETTTVFTI 499

Query: 184  LPVGYSLEIATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTASEMGTERAMGLS 243
               G     A+   S++  +++    + + S+E  E      T S T SE  T    GL 
Sbjct: 500  ---GSDTTTASTEGSETTAVSATGSEMTTVSTEGSENT----TVSTTGSETTTVSTTGLE 552

Query: 244  EEWTVH--SQEATTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASSPLLD 301
               T    S+  T S            G  TT +    S    +S      T AS+   +
Sbjct: 553  TTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSE 612

Query: 302  LSSSSES-TEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVSKTEGFP 360
             +S+S + +E    ST    ++ + T+     TV T     T+ S T S   ++ TEG  
Sbjct: 613  TTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSE 672

Query: 361  KDSRIATTSSSVLL---SPSAVESRRNSRVT--GNPGDEEFIEPSTENEFGLTSLRWQND 415
              +  AT S + +    S +   S   S  T     G E  I  +  +E    S+     
Sbjct: 673  TTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTITSTEGSEITTASITGSET 732

Query: 416  SPTFGEHQLASSSEVQNGSPMSQTETVSRSV-APMRGGEITAHWLLTNSTTSADVTGSSA 474
            +    E    +++  +     S + T S +  A     E T   ++ + TT A   GS  
Sbjct: 733  TTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSET 792

Query: 475  SYPEGVNASVLTQFSDS--------------TVQSGGSHTALGDRSYSESSSTSS---SE 517
            +     ++ + T F+++              TV + GS T     + SE+++T+S   SE
Sbjct: 793  TKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSE 852

Query: 518  SLNSSAPRGERSIAGISYGQVR-GTAIEQRTSSDHTDHTYLSSTFTKGERALLSITDNS- 575
            +  +S    E + A     +    T I   T++  T+ +  ++T T+G     + T+ S 
Sbjct: 853  TTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSE 912

Query: 576  ------SSSDIVESST------------SYIKISNSSHSEYSSFFHAQTERSNISSYDGE 617
                  + S+   +ST            S +   +++ SE  +     +E + +++   E
Sbjct: 913  ITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSE 972

Query: 618  YAQPST---ESPVLHTSNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSGP 674
                ST   E+  + T+   + T +I    T+ V  T +E  + S++ + ++ +S+    
Sbjct: 973  TTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSE 1032

Query: 675  PLPLPSV-SQSHHLFSS----ILPSTRASVHLLKSTSDASTPWSSSPSPLPVSLTTS--- 726
               + +  S++  ++++       ST  S     ST+ + T  +S+      +++TS   
Sbjct: 1033 TTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSG 1092

Query: 727  -TSAPLSVSQTTLPQ-------------SSSTPVLPRARETPVTSFQTSTMTSFMTMLHS 772
             T+A  + S+TT                S +T V   + ET   S   S MT+  T +  
Sbjct: 1093 TTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSE 1152

Query: 773  SQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESSTEQTLPATS 832
            + T      ST   E   + +      +  TE ++  TT S      T +ST  +   T+
Sbjct: 1153 TTTV-----STIGSEATTSSAAGSEATTTSTEGSE-TTTASTAGSETTTASTAGSETTTA 1206

Query: 833  TNLAQMSPTFTTTILKTSQPLMTTPGTLSSTASLVTGPIAVQTTAGKQ---LSLTHPEIL 889
            +     + T  TT  +TS P  ++ G+ ++TA ++     + +TA  +    SLT  E  
Sbjct: 1207 STSGSETNTACTTGSETSTP--SSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETT 1264

Query: 890  VPQISTEGGIS-----TERNRVIVDAT-TGLIPLTSVPTSAKEMT-TKLGVTAEYSPASR 942
               I+  G  +     +    V+  AT   + P+T+ P S    T T+L        AS 
Sbjct: 1265 TVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRL-------TASS 1317

Query: 943  SLGTSPSPQTTVVSTAEDLAPKSA--TFAVQSSTQSPTTVSSSASVNS 988
            S+  +P    T  S A    P     T  + +ST   ++ +S+  V +
Sbjct: 1318 SVTMAPGMDFT-ASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRT 1364



 Score =  106 bits (264), Expect = 2e-22
 Identities = 191/857 (22%), Positives = 343/857 (40%), Gaps = 147/857 (17%)

Query: 230 TASEMGTERAMGLSEEWTVHSQEATTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLH 289
           TAS  G+E    L     + + E TT++ + S        E TTPS       P  S   
Sbjct: 17  TASTTGSETTTIL-----IKASETTTASTAGS--------ETTTPS-------PTGSQTT 56

Query: 290 FYRTAASSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVS 349
               + S      ++ SE+T   +  +G  ++S++ ++T    TV T G   T  S+T +
Sbjct: 57  IVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSET----TVSTAGSETTTVSITGT 112

Query: 350 LGPVSKTEGFPKDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTS 409
              +    G    +   T+S + + S +  E+   S V    G E     + ++E    S
Sbjct: 113 ETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTV----GSETTTAYTADSETTAAS 168

Query: 410 LRWQNDSPTFGEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADV 469
                 +  F     A S  +   +  S+T TVS +     G E T     T STT ++ 
Sbjct: 169 TTGSEMTTVF----TAGSETITPSTAGSETTTVSTA-----GSETT-----TVSTTGSET 214

Query: 470 TGSSASYPEGVNAS--------VLTQFSDSTVQSGGS------------HTALGDRSYSE 509
           T +S ++ E   AS        V T  S++TV + GS            +TA  + S + 
Sbjct: 215 TTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTT 274

Query: 510 SSSTSSSESLNSSAPRGERSIAGISYGQ-VRGTAIEQRTSSDHTDHTYLSSTFTKGERAL 568
           ++ST+  E+  +S    E ++A     +    + I   T+   T  + +++ F  G   +
Sbjct: 275 TASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETI 334

Query: 569 LSITDNSSSSDIVESSTSYIKISNSSHSEYSSFFHAQTERSNISSYDGEYAQPSTE-SPV 627
            + T  S ++  V ++ S    ++   SE S+     +E +  S+   E    STE S  
Sbjct: 335 RASTVGSETT-TVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEA 393

Query: 628 LHTSNLPSYTPTINMPNT---------------------SVVLDTDAEFVSDSSSSSSSS 666
              S   S T T+++ ++                     +    T+   ++ +S+S S +
Sbjct: 394 TTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSET 453

Query: 667 SSSSSSGPPLPLPSV--SQSHHLFSSILPSTRASVHLLKST------SDASTPWSSSPSP 718
           +++S+ G      +   S++   +++   +T AS   L++T      SD +T  +     
Sbjct: 454 TTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSET 513

Query: 719 LPVSLTTSTSAPLSV---SQTTLPQ--SSSTPVLPRARETPVTSFQTSTMTSFMT----- 768
             VS T S    +S      TT+    S +T V     ET  TS + S MT+  T     
Sbjct: 514 TAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAET 573

Query: 769 -------------MLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPL 815
                            S+T  + +  + +      +S++ S  +  +E+T A TT+S  
Sbjct: 574 TTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSET 633

Query: 816 PPSLTESSTEQTLPATSTNLAQMSPT------------FTTTILKT-SQPLMTTPGTLSS 862
             + TE S   T+  T +    +S T             TTT+  T S+  ++T G+ ++
Sbjct: 634 TTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTT 693

Query: 863 TASLVTGPIAVQTTAGKQLSLTH---PEILVPQI--------STEGG----ISTERNRVI 907
           T S+        +T G + ++T     EI    I        STEG      STE +   
Sbjct: 694 TVSITGSETTKVSTTGSETTITSTEGSEITTASITGSETTTASTEGSETTTASTEGSETT 753

Query: 908 VDATTGLIPLTSVPTSAKEMTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSAT 967
             +TTG    T+  TS++  TT   +    +  + ++G+  +  +T  S    +  +++ 
Sbjct: 754 SASTTGSETTTASTTSSE--TTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSE 811

Query: 968 FAVQSSTQSPTTVSSSA 984
             + S+T S TT  S+A
Sbjct: 812 TTIASTTASETTTVSTA 828



 Score = 93.6 bits (231), Expect = 1e-18
 Identities = 138/603 (22%), Positives = 237/603 (39%), Gaps = 69/603 (11%)

Query: 445 SVAPMRGGEITAHWLLTNSTTSADVTGSSASYPE---------GVNASVLTQFS-----D 490
           + A   G E T   +  + TT+A   GS  + P           ++ S +T  S     +
Sbjct: 16  TTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSEN 75

Query: 491 STVQSGGSHTALGDRSYSESS-STSSSESLNSSAPRGERSIAGISYGQVRGTAIEQRTSS 549
           +TV S GS T     + SE++ ST+ SE+          SI G     V     E  T+S
Sbjct: 76  TTVSSAGSGTTTASMAGSETTVSTAGSETTTV-------SITGTETTMVSAMGSETTTNS 128

Query: 550 DHTDHTYLSSTFTKGERALLSITDNSSSSDIVESSTSYIKISNSSHSEYSSFFHAQTERS 609
             +  T ++ST       + ++   ++++   +S T+    ++++ SE ++ F A +E  
Sbjct: 129 TTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETT---AASTTGSEMTTVFTAGSETI 185

Query: 610 NISSYDGEYAQPST---ESPVLHTSNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSS 666
             S+   E    ST   E+  + T+   + T +     T+      +E    S++ S ++
Sbjct: 186 TPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETT 245

Query: 667 SSSSSSGPPLPLPSVSQSHHLFSSILPSTRASVHLLKSTSDASTPWSSSPSPLPVSLTTS 726
            S++ S         S+++  F+    +T AS    ++T+ AST  S       +   T+
Sbjct: 246 VSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTA-ASTTGSEPTMASTMGSETT 304

Query: 727 TSAPLSVSQTTLPQSSS--TPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADL-----K 779
            ++ +    T +  +SS  T V     ET   S   S  T+  T    + TA +      
Sbjct: 305 MASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETS 364

Query: 780 SQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESSTEQTLPATSTNLAQMS 839
           + ST   E     ++     +  TE ++A T ++    + T S T+     T T  ++M+
Sbjct: 365 TDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMT 424

Query: 840 PTFTT--------------TILKTSQPLMTTPGTLSSTASLVT----GPIAVQTTAGKQL 881
              TT              TI  TS    TT  T  S  + VT          TT  +  
Sbjct: 425 AVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETT 484

Query: 882 SLTHPEILVPQISTEGG----ISTERNRVIVDATTGLIPLTSVPTSAKEMTTKLGVTAEY 937
           + ++  +    + T G      STE +     + TG   +T+V T   E TT     +E 
Sbjct: 485 TASNTGLETTTVFTIGSDTTTASTEGSETTAVSATG-SEMTTVSTEGSENTTVSTTGSET 543

Query: 938 SPAS------RSLGTSPSPQTTV----VSTAEDLAPKSATFAVQSSTQSPTTVSSSASVN 987
           +  S       +  T  S  TTV      T  D    S T A  ++    TTVS++ S N
Sbjct: 544 TTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSEN 603

Query: 988 SCA 990
           + A
Sbjct: 604 TTA 606



 Score = 75.1 bits (183), Expect = 4e-13
 Identities = 146/624 (23%), Positives = 255/624 (40%), Gaps = 74/624 (11%)

Query: 116  NTEAHVENITFYQNQEDFSTVSS--KEGVMVQTSGK---SHAASDAPENLTLLAETADAR 170
            N+E  + + T      + +TVS+   E +   T+G    +  +++  E  T   E ++  
Sbjct: 809  NSETTIASTT----ASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETT 864

Query: 171  GRSGSSSRTNFTILPVGYSLEIATALTSQSGNLASESLHLPSSSSEFDE--RIAAFQTKS 228
              S  SS T  T   +G     A+   S++   ++E     ++S+E  E   ++   +++
Sbjct: 865  TASTESSETT-TATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSET 923

Query: 229  GTASEMGTERAMGLSEEW------TVHSQEATTSAWSPSFLPALEMGELTTPSRKRNSSG 282
             TAS  G+E     +E        T  S+  T SA          MG  TT +    S  
Sbjct: 924  TTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSET 983

Query: 283  PDLSWLHFYRTAASSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRT 342
              +S      TA S         SE+T    +STG ++++VS T T    T  T+G   T
Sbjct: 984  TTVS------TAGSETTTASIEGSETTTV--SSTGSETTTVSTTGTETTITS-TEGSETT 1034

Query: 343  LRSLTVSLGPVSKTEGFPKDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTE 402
                TV+      T  +   S   TTS+      + V +  +   T +  D E    ST 
Sbjct: 1035 ----TVTTAGSETTAVYTTGSETTTTSTEGS-ETTTVSTTGSETTTASTADLETTTVSTS 1089

Query: 403  NEFGLTSLRWQNDSPTF---GEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWL 459
                 T+    +++ T    G     +S+E    + +S T + + + A   G E+T  + 
Sbjct: 1090 GSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSET-TTASTTGSEMTTVFT 1148

Query: 460  LTNSTTS-----ADVTGSSASYPEGVNASVLTQFSDSTVQS-GGSHTALGDRSYSESSST 513
              + TT+     ++ T SSA+  E    S  T+ S++T  S  GS T     + SE+++ 
Sbjct: 1149 TVSETTTVSTIGSEATTSSAAGSEATTTS--TEGSETTTASTAGSETTTASTAGSETTTA 1206

Query: 514  SSSES-LNSSAPRGERSIAGISYGQVRGTAI---EQRTSSDHTDHTYLSSTFTKGERALL 569
            S+S S  N++   G  +    S G    TA     + T +        +++ T  E   +
Sbjct: 1207 STSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTV 1266

Query: 570  SIT-DNSSSSDIVESSTSYI----------KISNSSHSEYSSFFHAQTERSNIS-----S 613
            SIT   ++++    SST+++           I+N+  S   +     T  S+++      
Sbjct: 1267 SITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMD 1326

Query: 614  YDGEYAQPSTESPVLHTSNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSSSSSS--S 671
            +    A  +    VL+TS L   T T+   +T     T A  V  ++ S+   +SS+   
Sbjct: 1327 FTASAASHTVPGIVLNTSGLG--TSTMGASST-----TSAHGVRTTTGSTREPTSSTFQE 1379

Query: 672  SGP-PLPLPSVSQSHHLFSSILPS 694
            +GP  +   +VS SH   + I PS
Sbjct: 1380 TGPVSMGTNTVSMSHTPTNVIKPS 1403



 Score = 61.2 bits (147), Expect = 6e-09
 Identities = 106/542 (19%), Positives = 202/542 (37%), Gaps = 41/542 (7%)

Query: 644  NTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSILPSTRASVHLLK 703
            NT+    T +E  +     +S ++++S++G     PS + S    ++I+  + + +    
Sbjct: 14   NTTTASTTGSE-TTTILIKASETTTASTAGSETTTPSPTGSQ---TTIVSISGSEITTTS 69

Query: 704  STSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQSSSTPVLPRARETPVTSFQTSTM 763
            +    +T  SS+ S      TT++ A    + +T    ++T  +     T V++  + T 
Sbjct: 70   TAGSENTTVSSAGS----GTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETT 125

Query: 764  TSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESS 823
            T+  T   ++ T+   S++T         S++ +  +  +E+T A TT S +    T  S
Sbjct: 126  TNSTTSSETTVTSTAGSETTTVS---TVGSETTTAYTADSETTAASTTGSEMTTVFTAGS 182

Query: 824  TEQTLPATSTNLAQMSPTFTTTILKTSQPLMTTPGTLSSTASLVTGPIAVQTTAGKQLSL 883
             E   P+T+      S T T +   +    ++T G+ ++TAS         +T G + + 
Sbjct: 183  -ETITPSTAG-----SETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTK 236

Query: 884  THPEILVPQISTEGGIST-------ERNRVIV-DATTGLIPLTSVPTSAKEMTTKLGVTA 935
                     +ST G  +T       E N     D+ T     T   T+A   T      A
Sbjct: 237  VSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMA 296

Query: 936  EYSPASRSLGTSPSPQTTVVSTAED-----LAPKSATFAVQSSTQSPTTVSSSASVNSCA 990
                +  ++ ++  P+TT VSTA        A  S T    +     TTVS++ S  + A
Sbjct: 297  STMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTA 356

Query: 991  VNPCLHNGECVADNTSRGYHCRCPPSWQGDDCSVDVNE-----CLSNPCPSTAMCNNTQG 1045
                +   E   D+T+         S +G + +    E      +S     T   + T  
Sbjct: 357  ---SIMGSETSTDSTTGSE--TTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDS 411

Query: 1046 SFICKCPVGYQLEKGICNLVRTFVTEFKLKRTFLNTTVEKHSDLQEVENEITKTLNMCFS 1105
                 C  G ++      +  T     +     + +T +  +     E   T T+    S
Sbjct: 412  ETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGS 471

Query: 1106 ALPSYIRSTVHASRESNAVVISLQTTFSLASNVTLFDLADRMQKCVNSCKSSAEVCQLLG 1165
               +   +    +  SN   +   T F++ S+ T           V++  S        G
Sbjct: 472  ETKTAYTTGSETTTASN-TGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEG 530

Query: 1166 SQ 1167
            S+
Sbjct: 531  SE 532


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score =  122 bits (305), Expect = 3e-27
 Identities = 216/932 (23%), Positives = 373/932 (40%), Gaps = 93/932 (9%)

Query: 129  NQEDFSTVSSKEGVMVQTSGKSHAASDAP-ENLTLLAETADARGRSGSSSRTNFTILPVG 187
            + + F T +S+      T+  +  A+  P E  T L     +     SS  +N +  PV 
Sbjct: 419  DSKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVD 478

Query: 188  YSLEIATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTASEMGTERAMGLSEEWT 247
               ++ T+  + S    +E   +P+S+    E      + S +   + +  A  LS    
Sbjct: 479  SKTQVTTSTEASSSPPTAEVNSMPTSTPS--EGSTPLTSMSVSTMPVASSEASTLSTTPV 536

Query: 248  VHSQEATTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASSPLLDLSSS-S 306
              S   TTS+ + S     E   + T +    S+ P  +     R   SS     S++ +
Sbjct: 537  DTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGST-PLTNMPVSTRLVVSSEASTTSTTPA 595

Query: 307  ESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVSKTEGF-----PK 361
            +S   +  S+   SSS +   T    + +++ G  T+ S++VS   V+ +E       P 
Sbjct: 596  DSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGT-TITSMSVSTTLVASSEASTLSTTPV 654

Query: 362  DSRIATTSSSVLLS----------PSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSLR 411
            DS    T+S+   S          P++  +  ++ +T  P +   +  S  +    T + 
Sbjct: 655  DSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPV- 713

Query: 412  WQNDSPTFGEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADVTG 471
                +P     + +SS    +G+ M  T T S    P+    ++   LLT+S  S   T 
Sbjct: 714  -DTSTPVTTSTEASSSPTTADGASMP-TSTPSEGSTPLTSMPVSKT-LLTSSEAS---TL 767

Query: 472  SSASYPEGVNASVLTQFSDSTVQSGGSHTALGDRSYSESSSTSSSESLN--SSAPRGERS 529
            S+       + +  T+ S S   + G+   +   S      TS   S+   +S      S
Sbjct: 768  STTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPVTSPEASTLS 827

Query: 530  IAGISYGQVRGTAIEQRTSSDHTDHTYL-SSTFTKGERALLSI---TDNSSSSDIVESST 585
               +       T+ E  +S    + T + +ST+++G   L S+   T   ++S I   ST
Sbjct: 828  TTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVATSAISTLST 887

Query: 586  SYIKISN--SSHSEYSSFFHAQTERSNISSYDGEYAQPSTESPVLHTSNLPSYTPTINMP 643
            + +  S   ++ +E  S        S  +S  GE + P T  P   T  + S   T++  
Sbjct: 888  TPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSAT 947

Query: 644  --NTSVVLDTDAEFVSDSSSSSSSS-SSSSSSGPPLPLPSVSQSHHLFSSILPSTRASVH 700
              +TS  + T  E  S  +++  +S  +S+ S    PL S   SH L ++   ST ++  
Sbjct: 948  PVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTP 1007

Query: 701  LLKSTSDASTPWSSSPSP------LPVSLTTSTSAPLS--VSQTTLPQSSSTPVL---PR 749
            +  +T   ++  +SSP P      +P S  +  S PL+     TT+  SS T  L   P 
Sbjct: 1008 VDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPA 1067

Query: 750  ARETPVTSFQ-------TSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLP 802
               TPVT++        T+  TS  T  +S  +  L   S P   +++  S++ +L + P
Sbjct: 1068 DTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPL--TSVPVSTRLVVSSEASTLSTTP 1125

Query: 803  TESTKAVTTNSPLPPSLTESSTEQTLPATSTNLAQMSPTFTTTILKTSQPLMTTPGTLSS 862
             +++  VTT+       TE+S+  T  A  T++    P+  TT L  S P+ TT    S 
Sbjct: 1126 VDTSIPVTTS-------TEASSSPT-TAEGTSIPTSPPSEGTTPL-ASMPVSTTLVVSSE 1176

Query: 863  TASLVTGPIAVQTTAGKQLSLTHP----EILVPQISTEGGISTERNRVIVDATTGLIPLT 918
              +L T P+  +T        + P    E+     ST G  ST              PLT
Sbjct: 1177 ANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERST--------------PLT 1222

Query: 919  SVP------TSAKEMTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSATFAVQS 972
            S+P       S++  T         +P + S  TS SP TT   T+   +  S    + +
Sbjct: 1223 SMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSP-TTAEGTSLPTSTTSEGSTLLT 1281

Query: 973  STQSPTTVSSSASVNSCAVNPCLHNGECVADN 1004
            S    TT+ +S   ++    P    G  V  N
Sbjct: 1282 SIPVSTTLVTSPEASTLLTTPVDTKGPVVTSN 1313



 Score =  120 bits (301), Expect = 9e-27
 Identities = 243/1046 (23%), Positives = 387/1046 (36%), Gaps = 131/1046 (12%)

Query: 24   PPAAPGTRDPPPSPARRALSLAPLAGAGLELQLERRPEREPPPTPPRERRGPATPGPSYR 83
            P  A GT  P   P+       PLA   +   L    E     T P + +          
Sbjct: 1142 PTTAEGTSIPTSPPSE---GTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEAS 1198

Query: 84   APEPGAATQRGPSGRAPRGGSADAAW--KHWPESNTEAHVENITFYQNQEDFSTVSSKEG 141
            +P P A     P+       +   +   +H P +++EA   + +        +T +    
Sbjct: 1199 SPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSS 1258

Query: 142  VMVQTSGKSHAASDAPENLTLLAETADARGRSGSSSRTNFTILPVGYSLEIATALTSQSG 201
                  G S   S   E  TLL     +     S   +     PV     + T+    S 
Sbjct: 1259 SPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSS 1318

Query: 202  NLASESLHLPSSSSEFDERIAAFQTKSGTASEMGTERAMGLSEEWTVHSQEATTSAWSPS 261
               +E   +P+S+  + E      +     + + +     LS     +S   TTS  + S
Sbjct: 1319 PTPAEGTSMPTST--YSEGRTPLTSIPVNTTLVASSAISILSTTPVDNSTPVTTSTEACS 1376

Query: 262  FLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASSPLLDLSSSSESTEKLNNSTGLQSS 321
              P    G     S     + P  S         SS    LS++   T     ++   +S
Sbjct: 1377 S-PTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPGTTSAEATS 1435

Query: 322  SVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVSKTEGF-----PKDSRI-ATTSSSVLLS 375
            S +  + + + T     G   L+S+ VS  PV+ +E       P DS     TS++V  S
Sbjct: 1436 SPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLSTTPVDSNSPVVTSTAVSSS 1495

Query: 376  PSAVE---------SRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQNDSPTFGEHQLAS 426
            P+  E         S  ++ +T  P     +  S  N    T         T+   Q +S
Sbjct: 1496 PTPAEGTSIAISTPSEGSTALTSIPVSTTTVASSEINSLSTTPAVTSTPVTTYS--QASS 1553

Query: 427  SSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADVTGSSASYPEGVNASVLT 486
            S    +G+ M QT T S    P+    ++   ++++   +   T   +        +  T
Sbjct: 1554 SPTTADGTSM-QTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDSK----TQVTAST 1608

Query: 487  QFSDSTVQSGGSHTALGDRSYSESSSTSSSESLNSSAPRGERSIAGISYGQVRGTAIEQR 546
            + S ST   G S T          S+ S    L +S P     +A      +  T ++  
Sbjct: 1609 EASSSTTAEGSSMTI---------STPSEGSPLLTSIPVSTTPVASPEASTLSTTPVDSN 1659

Query: 547  T--------SSDHTDHTYLS---STFTKGERALLSITDNSS---SSDIVESSTSYIK--- 589
            +        SS  T     S   ST+T+G   L SIT  ++   SS I   ST+ +    
Sbjct: 1660 SPVITSTEVSSSPTPAEGTSMPTSTYTEGRTPLTSITVRTTPVASSAISTLSTTPVDNST 1719

Query: 590  -ISNSSHSEYSSFFHAQTERSNISSYDGEYAQPSTESPVLHTSNLPSYTPTINMP--NTS 646
             ++ S+ +  S      T   N +  +G    P T  PV  T  L S   T++    +TS
Sbjct: 1720 PVTTSTEARSSPTTSEGTSMPNSTPSEG--TTPLTSIPVSTTPVLSSEASTLSATPIDTS 1777

Query: 647  VVLDTDAEFVSDSSSSSSSSSSSSSSGPPL-PLPSVSQSHHLFSSILPSTRASVHL-LKS 704
              + T  E  S  +++  +S  +S+    + PL S   SH L ++   ST ++  +   S
Sbjct: 1778 TPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNS 1837

Query: 705  TSDASTPWSSSPSP--------------------LPVSLTT----------STSAPLSVS 734
                ST  SSSP+P                    +PVS TT          +T A  S  
Sbjct: 1838 PVVTSTAVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVASSETNTLSTTPAVTSTP 1897

Query: 735  QTTLPQSSSTPVL----------PRARETPVTSFQTSTMTSFMTMLHSSQTADLKSQSTP 784
             TT  Q SS+P            PR    P+TS   ST     T + SS+   L +    
Sbjct: 1898 VTTYAQVSSSPTTADGSSMPTSTPREGRPPLTSIPVST-----TTVASSEINTLSTTLAD 1952

Query: 785  HQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESSTEQTLPATSTNLAQMS--PTF 842
             +  V T S++ S        T A  T+ P  P+ +E ST  T    ST L   S   T 
Sbjct: 1953 TRTPVTTYSQASS------SPTTADGTSMP-TPAYSEGSTPLTSMPLSTTLVVSSEASTL 2005

Query: 843  TTTILKTSQPLMTTPGTLSSTASLVTGPIAVQTTAGKQLSLTHPEILVPQISTEGGISTE 902
            +TT + TS P   T  T  S++    G  ++QT+   +   T P   +P +ST   +S+E
Sbjct: 2006 STTPVDTSTP--ATTSTEGSSSPTTAGGTSIQTSTPSE--RTTPLAGMP-VSTTLVVSSE 2060

Query: 903  RNRVI---VDATTGLIPLTSVPTSAKEMTTKLGVTA--EYSPASRSLGTSPSPQTTVVST 957
             N +    VD+ T +   T   +SA    + + ++A  E SP   S+  S +P  +  ++
Sbjct: 2061 GNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLLTSIPLSTTPVASPEAS 2120

Query: 958  AEDLAPKSATFAVQSSTQSPTTVSSS 983
                 P  +   V +ST+    VSSS
Sbjct: 2121 TLSTTPVDSNSPVITSTE----VSSS 2142



 Score =  117 bits (294), Expect = 6e-26
 Identities = 245/1055 (23%), Positives = 400/1055 (37%), Gaps = 148/1055 (14%)

Query: 24   PPAAPGTRDPPPSPARRALSLAPLAGAGLELQLERRPEREPPPTPPRERRGP---ATPGP 80
            P  A GT     +P+ R     PLAG  +   L    E     T P + +     +T   
Sbjct: 2026 PTTAGGTSIQTSTPSERT---TPLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEAS 2082

Query: 81   SYRAPEPGAATQRGPSGRAPRGGSADAAWKHWPESNTEAHVENITFYQNQEDFSTVSSKE 140
            S    E  + T   PS  +P   S   +    P ++ EA   + T   +     T +   
Sbjct: 2083 SSATAEGSSMTISAPSEGSPLLTSIPLSTT--PVASPEASTLSTTPVDSNSPVITSTEVS 2140

Query: 141  GVMVQTSGKSHAASDAPENLTLLAETADARGRSGSSSRTNFTILPVGYSLEIATALTSQS 200
               + T G S   S   +  T L     +     SS+ +  +  PV  S  +  +  ++S
Sbjct: 2141 SSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARS 2200

Query: 201  GNLASESLHLPSSSSEFDERIAAFQTKSGTASEMGTERAMGLSEEWTVHSQEATTSAWSP 260
                SE   +P+S+    E    F +   +   + T  A  LS      S   TTS  + 
Sbjct: 2201 SPTTSEGTSMPTSTPS--EGSTPFTSMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEAT 2258

Query: 261  SF--------LPALEMGELTTPSRK--------RNSSGPDLSWLHF-------YRTAASS 297
            S         +P   + E TTP            NS    LS             T ASS
Sbjct: 2259 SSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASS 2318

Query: 298  P-------LLDLSSSSESTEKLNNS-------TGLQSSSVSQTK--TMHVATVFTDGG-- 339
            P        +  S+SSE    L             ++S++S T   T    T ++  G  
Sbjct: 2319 PPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSS 2378

Query: 340  PRT-----------------LRSLTVSLGPVSKTEGFPKDSRIATTSSSVLLSPSAVESR 382
            P T                 L S+ VS  PV  +E     +    TS+ V  S  A  S 
Sbjct: 2379 PTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSP 2438

Query: 383  RNSRVTGNPGDEEFIEPSTENEFGLTSLRWQNDSPTFGEHQLASSSEVQNGSPMSQTETV 442
              +  T  P       P +E    L S+          E    S++ V   +PM+ +   
Sbjct: 2439 TTAEGTSIP-----TSPPSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEA 2493

Query: 443  SRS-------VAPMRGGEITAHWLLTNSTTSADVTGSSASY----PEGVNASVLTQFSDS 491
            S S       V P+      +  L +   ++  V    AS     P   N+ V+T    S
Sbjct: 2494 SSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPEASTLSTTPVDSNSPVVTSTEIS 2553

Query: 492  TVQSGGSHTALGDRSYSESSSTSSSESLNSSAPRGERSIAGISYGQVRGTAIEQRTSSDH 551
            +  +    T++   +YSE S+   S  + S+ P      + +S   V  T+I   TS++ 
Sbjct: 2554 SSATSAEGTSMPTSTYSEGSTPLRSMPV-STKPLASSEASTLSTTPV-DTSIPVTTSTET 2611

Query: 552  TDHTYLSSTFTKGERALLSITDNSSSSDIVESSTSYIKISNSSHSEYSSFFHAQTERSNI 611
            +     SS  T  + ++   T +  S+ +     S + +++S  S  S+       R+ +
Sbjct: 2612 S-----SSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLSTT--PVDTRTLV 2664

Query: 612  SSYDGEYAQPSTESPVLHTSNLPSYTP-TINMPNTSVVLDTDAEFVSDSSSSSSSSSSSS 670
            ++  G  + P+T       S++P+ TP   + P T++++ T    +++S +S+ S++   
Sbjct: 2665 TTSTGTSSSPTTAEG----SSMPTSTPGERSTPLTNILVSTT--LLANSEASTLSTTPVD 2718

Query: 671  SSGPPLPLPSVSQSHHLFSSILPSTRASVHLLKST-SDASTPWSSS-PSPLPVSLTTSTS 728
            +S P       S S        P+T     +  ST SD STP +S   S LPV+ + +++
Sbjct: 2719 TSTPVTTSAEASSS--------PTTAEGTSMRISTPSDGSTPLTSILVSTLPVASSEAST 2770

Query: 729  APLSVSQTTLPQSSSTPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADLKSQSTPHQEK 788
               +   T++P ++ST          VTS  TST +   T L           S P    
Sbjct: 2771 VSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPL----------TSMPVNHT 2820

Query: 789  VITESKSPSLVSLPTESTKAVTTNSPLPPSLTESSTEQTLPATSTNLAQMSPTFTTTILK 848
             +  S++ +L      ST  V T++P+  S   SS+  T       ++  S   T   L 
Sbjct: 2821 PVASSEAGTL------STTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEGST---LL 2871

Query: 849  TSQPLMTTPGTLSSTASLVTGP----IAVQTTAGKQLSLTHPEILVPQISTEGGISTERN 904
            TS P+ TTP   S  ++L T P    I V T+     S T  E     IST   +ST   
Sbjct: 2872 TSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLT 2931

Query: 905  RVIVD------------ATTGLIPLTSVPTSAKEMTTKLGVTAEYSPASRSLGTSPSPQT 952
             ++V             +TT +   T V TSA+  ++         P S + G   +P T
Sbjct: 2932 SILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPIS-TPGERRTPLT 2990

Query: 953  TV-VSTAEDLAPKSATFA-VQSSTQSPTTVSSSAS 985
            ++ VST    + +++T +   + T +P T S+ AS
Sbjct: 2991 SMSVSTMPVASSEASTLSRTPADTSTPVTTSTEAS 3025



 Score =  117 bits (294), Expect = 6e-26
 Identities = 242/1063 (22%), Positives = 392/1063 (36%), Gaps = 189/1063 (17%)

Query: 24   PPAAPGTRDPPPSPARRALSLAPLAGAGLELQLERRPEREPPPTPPRERRGPATPGPSYR 83
            P  A GT  P  + +       PL    +   L    E     T P +   P T      
Sbjct: 2261 PTTAEGTSIPTSTLSE---GTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEAS 2317

Query: 84   APEPGAATQRGPSGRAPRGGSADAAWKHWPESNTE-AHVENITFYQNQEDFST---VSSK 139
            +P P A     P+  +  G +        P S T  A  E  T      D ST     S+
Sbjct: 2318 SPPPTAEGTSMPTSTSSEGNTP---LTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQ 2374

Query: 140  EGVMVQTSGK-SHAASDAPENLTLLAETADARGRSGSSSRTNFTILPVGYSLEIATALTS 198
             G    T+   S   S   E  T L     +     SS  +  +  PV  S  + T+  +
Sbjct: 2375 AGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEA 2434

Query: 199  QSGNLASESLHLPSSS-SEFDERIAAF--QTKSGTASEMGTERAMGLSEEWTVHSQEATT 255
             S    +E   +P+S  SE    +A+    T    +SE GT     LS      S   TT
Sbjct: 2435 SSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSEAGT-----LSTTPVDTSTPMTT 2489

Query: 256  SAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASSPLLDLSSSS--ESTEKLN 313
            S  + S     E  ++  P    +     L+ +    T  +SP     S++  +S   + 
Sbjct: 2490 STEASSSPTTAE--DIVVPISTASEGSTLLTSIPVSTTPVASPEASTLSTTPVDSNSPVV 2547

Query: 314  NSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVSKTEGFPKDSRIATTSSSVL 373
             ST + SS+ S   T    + +++G    LRS+ VS  P++ +E     +    TS  V 
Sbjct: 2548 TSTEISSSATSAEGTSMPTSTYSEGST-PLRSMPVSTKPLASSEASTLSTTPVDTSIPVT 2606

Query: 374  LSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQNDSPTFGEHQLASSSEVQNG 433
             S     S   ++ T  P     I   +E    LTS+                   + + 
Sbjct: 2607 TSTETSSSPTTAKDTSMP-----ISTPSEVSTSLTSI-------------------LVST 2642

Query: 434  SPMSQTETVSRSVAPMRGGEITAHWLLTNST--TSADVTGSSASYPEGVNASVLTQFSDS 491
             P++ +E  + S  P     +    L+T ST  +S+  T   +S P        T  ++ 
Sbjct: 2643 MPVASSEASTLSTTP-----VDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNI 2697

Query: 492  TVQSGGSHTALGDRSYSESSSTSSSESLNSSAPRGERSIAGISYGQVRGTAIEQRTSSDH 551
             V    S T L +      +ST S+  +++S P    + A  S     GT++   T SD 
Sbjct: 2698 LV----STTLLAN----SEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDG 2749

Query: 552  TDHTYLSSTFTKGERALLSITDNSSSSDIVESSTSYIKISNSSHSEYSSFFHAQTERSNI 611
            +  T L+S          ++   SS +  V ++     I  ++ +E SS        S  
Sbjct: 2750 S--TPLTSILVS------TLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMP 2801

Query: 612  SSYDGEYAQPSTESPVLHTSNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSSSSSSS 671
            +S   E + P T  PV HT    S   T++    +  +DT       ++S+ +SSS +++
Sbjct: 2802 TSTPSETSTPLTSMPVNHTPVASSEAGTLS----TTPVDTSTPV---TTSTKASSSPTTA 2854

Query: 672  SGPPLPLPSVSQSHHLFSSILPSTR----------------ASVHLLKSTSDASTPWSSS 715
             G  +P+ + S+   L +SI  ST                  S+ +  ST  +S+P ++ 
Sbjct: 2855 EGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAE 2914

Query: 716  PSPLPVSLTTSTSAPL-SVSQTTLPQS-------SSTPV--------------------- 746
             + +P+S  +  S PL S+  +T+P +       S+TPV                     
Sbjct: 2915 GTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEG 2974

Query: 747  ------LPRARETPVTSFQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSL-- 798
                   P  R TP+TS   STM      + SS+ + L          V T +++ S   
Sbjct: 2975 TSMPISTPGERRTPLTSMSVSTMP-----VASSEASTLSRTPADTSTPVTTSTEASSSPT 3029

Query: 799  --------VSLPTESTKAVTTN--SPLPPSLTESSTEQTLPATSTNLAQMSPTFTTTILK 848
                    +S P+E +  +T+   S  P ++ E+ST  T P  S      SP  T+T + 
Sbjct: 3030 TAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSN-----SPVVTSTEVS 3084

Query: 849  TSQ-----------------------PLMTTPGTLSSTASLVTGPIAVQTTAGKQLSLTH 885
            +S                        P+ TTP T S+ ++L T P+   T        T 
Sbjct: 3085 SSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPV-----TTS 3139

Query: 886  PEILVPQISTEGGISTERNRVIVDATTGLIPLTSVPTSAKEMTTKLGVTAEYSPASRSLG 945
             E      ++EG      +      + G  PLT +P S   + +    T   +P   S  
Sbjct: 3140 TEAHSSPTTSEG-----TSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTP 3194

Query: 946  TSPSPQTTVVSTAEDLA-----PKSATFAVQSSTQSPTTVSSS 983
             + S + T  +TAE  +     P      + S   S T V+SS
Sbjct: 3195 VTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASS 3237



 Score =  117 bits (293), Expect = 8e-26
 Identities = 255/1108 (23%), Positives = 411/1108 (37%), Gaps = 181/1108 (16%)

Query: 24   PPAAPGTRDPPPSPARRALSLAPLAGAGLELQLERRPEREPPPTPPRERRGPATPGPSYR 83
            P  A GT  P  +P+       PL    +   L    E     T P +   P T      
Sbjct: 965  PTTAEGTSIPTSTPSE---GTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEAS 1021

Query: 84   APEPGAATQRGPSGRAPRGGSADAAWKHWPESNTE-AHVENITFYQNQEDFST----VSS 138
            +P P A     P+   P  GS        P S T  A  E  T      D ST     S 
Sbjct: 1022 SPPPTAEGTSMPTS-TPSEGSTPLT--RMPVSTTMVASSETSTLSTTPADTSTPVTTYSQ 1078

Query: 139  KEGVMVQTSGKSHAASDAPENLTLLAETADARGRSGSSSRTNFTILPVGYSLEIATALTS 198
                     G S   S   E  T L     +     SS  +  +  PV  S+ + T+  +
Sbjct: 1079 ASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEA 1138

Query: 199  QSGNLASESLHLPSSS-SEFDERIAAF--QTKSGTASEMGTERAMGLSEEWTVHSQEATT 255
             S    +E   +P+S  SE    +A+    T    +SE  T     LS        +  T
Sbjct: 1139 SSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSSEANT-----LSTTPVDSKTQVAT 1193

Query: 256  SAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASSPLLDLSSSSESTEKLNNS 315
            S  + S  P  E+  + T +    S+ P  S    +   ASS    LS+S   T     +
Sbjct: 1194 STEASSPPPTAEVTSMPTSTPGERST-PLTSMPVRHTPVASSEASTLSTSPVDTSTPVTT 1252

Query: 316  TGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVSKTEGF-----PKDSR-IATTS 369
            +   SSS +  +   + T  T  G   L S+ VS   V+  E       P D++    TS
Sbjct: 1253 SAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTS 1312

Query: 370  SSVLLSPSAVE---------SRRNSRVTGNPGDEEFIEPST---------ENEFGLTSLR 411
            + V  SP+  E         S   + +T  P +   +  S          +N   +T+  
Sbjct: 1313 NEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILSTTPVDNSTPVTTST 1372

Query: 412  WQNDSPTFGEHQLASSSEVQNGS------PMSQTETVSRSVAPMRGGEITAHWLLTNSTT 465
                SPT  E     +S    G+      P+S T  VS   + +    +      T  TT
Sbjct: 1373 EACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTS---TPGTT 1429

Query: 466  SADVTGSSASYPEGVNASVLTQFSDSTVQSG--GSHTALGDRSYSESSSTS--------S 515
            SA+ T SS +  EG++    T     T       S+T + +   S  S+T         +
Sbjct: 1430 SAEAT-SSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLSTTPVDSNSPVVT 1488

Query: 516  SESLNSSAPRGERSIAGISYGQVRGTAIEQR---------------------TSSDHTDH 554
            S +++SS    E +   IS      TA+                        TS+  T +
Sbjct: 1489 STAVSSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTVASSEINSLSTTPAVTSTPVTTY 1548

Query: 555  TYLSSTFTKGE-RALLSITDNSSSSDIVESSTSYIKISNSSHSEYSSF-------FHAQT 606
            +  SS+ T  +  ++ + T +  S+ +     S + + +S  +  S+          A T
Sbjct: 1549 SQASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTAST 1608

Query: 607  ERSNISSYDGE---YAQPSTESPVLHTSNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSS 663
            E S+ ++ +G     + PS  SP+L  +++P  T  +  P  S +  T  +  S   +S+
Sbjct: 1609 EASSSTTAEGSSMTISTPSEGSPLL--TSIPVSTTPVASPEASTLSTTPVDSNSPVITST 1666

Query: 664  S-SSSSSSSSGPPLPLPSVSQSHHLFSSIL----PSTRASVHLLKSTS-DASTPWSSS-- 715
              SSS + + G  +P  + ++     +SI     P   +++  L +T  D STP ++S  
Sbjct: 1667 EVSSSPTPAEGTSMPTSTYTEGRTPLTSITVRTTPVASSAISTLSTTPVDNSTPVTTSTE 1726

Query: 716  -------------PSPLPVSLTTS-TSAPLSVSQTTLPQSSSTPVLPRARETPVTSFQTS 761
                         P+  P   TT  TS P+S +     ++S+    P    TPVT+   +
Sbjct: 1727 ARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTTSTEA 1786

Query: 762  TMTSFMTMLHSSQTADLKS-----QSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLP 816
            T +       S  T+ L        STP    ++  S++ +L + P +S   V T++ + 
Sbjct: 1787 TSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAVS 1846

Query: 817  PSLTESSTEQTLPATSTNLAQMSPTFTTTILKTSQPLMTTPGTLSSTASLVTGPIAVQT- 875
             S T        PA  T++A  +P+  +T L TS P+ TT    S T +L T P    T 
Sbjct: 1847 SSPT--------PAEGTSIATSTPSEGSTAL-TSIPVSTTTVASSETNTLSTTPAVTSTP 1897

Query: 876  -TAGKQLSLT-----------------HPEILVPQISTEGGISTERNRVIVDATTGLIPL 917
             T   Q+S +                  P +    +ST    S+E N +         P+
Sbjct: 1898 VTTYAQVSSSPTTADGSSMPTSTPREGRPPLTSIPVSTTTVASSEINTLSTTLADTRTPV 1957

Query: 918  T-------------------------SVPTSAKEMTTKLGVTAEYSPASRSLGTSPSPQT 952
            T                         S P ++  ++T L V++E S  S +   + +P T
Sbjct: 1958 TTYSQASSSPTTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTPAT 2017

Query: 953  TVVSTAEDLAPKSA-TFAVQSSTQSPTT 979
            T  ST    +P +A   ++Q+ST S  T
Sbjct: 2018 T--STEGSSSPTTAGGTSIQTSTPSERT 2043



 Score =  117 bits (292), Expect = 1e-25
 Identities = 249/1122 (22%), Positives = 403/1122 (35%), Gaps = 189/1122 (16%)

Query: 24   PPAAPGTRDPPPSPARRALSLAPLAGAGLELQLERRPEREPPPTPPRERRGPATPGPSYR 83
            P  A G+  P  +P  R+    PL    +   L    E     T P +   P T      
Sbjct: 2674 PTTAEGSSMPTSTPGERS---TPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEAS 2730

Query: 84   APEPGAATQRGPSGR--APRGGSADAAW---KHWPESNTEAHVENITFYQNQEDFSTVSS 138
            +      T  G S R   P  GS           P +++EA   + T        +T + 
Sbjct: 2731 S---SPTTAEGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTE 2787

Query: 139  KEGVMVQTSGKSHAASDAPENLTLLAETADARGRSGSSSRTNFTILPVGYSLEIATALTS 198
                       S   S   E  T L           SS     +  PV  S  + T+  +
Sbjct: 2788 ASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKA 2847

Query: 199  QSGNLASESLHLP-SSSSEFDERIAAFQTKSGTASEMGTERAMGLSEEWTVHSQEATTSA 257
             S    +E + +P S++SE    + +    +   +            + ++    +T  +
Sbjct: 2848 SSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGS 2907

Query: 258  WSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASSPLLDLSSSSESTEKLNNSTG 317
             SP+      M  ++TPS     S P  S L      A S    LS++   T +   +T 
Sbjct: 2908 SSPTTAEGTSM-PISTPSEV---STPLTSILVSTVPVAGSEASTLSTTPVDT-RTPVTTS 2962

Query: 318  LQSSSVSQTKTMHVATVFTDGGPRT-LRSLTVSLGPVSKTEGFPKDSRIATTSSSVLLSP 376
             ++SS   T       + T G  RT L S++VS  PV+ +E        A TS+ V  S 
Sbjct: 2963 AEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTST 3022

Query: 377  SAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQNDSPTFGEHQLASSSEVQNGSPM 436
             A  S   +  TG P     I   +E    LTS+          E    S++ V + SP+
Sbjct: 3023 EASSSPTTAEGTGIP-----ISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPV 3077

Query: 437  SQTETVSRSVAPMRGGE----------------------ITAHWLLTNSTTSAD----VT 470
              +  VS S  P  G                        +T+  + T STT  D    VT
Sbjct: 3078 VTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVT 3137

Query: 471  GSSASYPEGVNASVLTQFSDSTVQSGGSHTALGDRS----YSESSSTSSSESLNSSAPRG 526
             S+ ++      S  T    ST   G +       S     S   ST S+  +++S P  
Sbjct: 3138 TSTEAH-SSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPV- 3195

Query: 527  ERSIAGISYGQVRGTAIEQRTSSD----------------HTDHTYLSSTFTKGERALLS 570
              S    S     GT+I   T S+                 ++ + LS+T       L +
Sbjct: 3196 TTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTT 3255

Query: 571  ITDNSSSSDIVESSTSYIKISNSSHSEYSSF-----FHAQTERSNISSYDGE-------Y 618
             T+ SSS    E ++      +   +  +S        A +E S +S+   +       Y
Sbjct: 3256 STEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTY 3315

Query: 619  AQPSTESPVLHTSNLPSYT------PTINMP-NTSVVLDTDAEFVSDS---------SSS 662
            +Q S+  P+   +++P+ T      P  NM  +T+ V+ ++A  +S +         +S+
Sbjct: 3316 SQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTST 3375

Query: 663  SSSSSSSSSSGPPLPLPSVSQSHHLFSSILPSTR----ASVHLLKSTS-------DASTP 711
             +S S +++ G  +P  S S+     +S+  ST     + V+ L +T          ST 
Sbjct: 3376 EASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPVDSNTLVTTSTE 3435

Query: 712  WSSSPS-----PLPVSLTTSTSAPLSVS--------------------QTTLPQSSSTPV 746
             SSSP+      LP S T+  S PLS+                      T+ P ++S+P 
Sbjct: 3436 ASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTTSSPT 3495

Query: 747  LPRARETPVTSFQTST----------MTSFMTMLHSSQTADLKSQSTPHQEKVITESKSP 796
                    VTS  TST          M    T + SS+ + L +        V + S++ 
Sbjct: 3496 NSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQAS 3555

Query: 797  SL----------VSLPTESTKAVTT-------------NSPLPPSL---------TESST 824
            S           +S P+E + ++TT             ++P  PS+         T+S++
Sbjct: 3556 SSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDRSTPVTTSTQSNS 3615

Query: 825  EQTLPATSTNLAQMSPTFTTTILKTSQPLMTTPGTLSSTASLVTGPIAVQTTAGKQLSLT 884
              T P   T L   +P+  +T L T  P+ TT  T+S   +  T P+   T         
Sbjct: 3616 TPTPPEVIT-LPMSTPSEVSTPL-TIMPVSTTSVTISEAGTASTLPVDTST--------- 3664

Query: 885  HPEILVPQISTEGGISTERNRVIVDATTGLIPLTSVPTSAKEMTTKLGVTAEYSPASRSL 944
             P I   Q+S+           I   + G  PLT++P S   +T+  G T        S 
Sbjct: 3665 -PVITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTPSVVTST 3723

Query: 945  GTSPSPQTTVVSTAEDLAPKSATFAVQSSTQSPTTVSSSASV 986
              + S +    S   D    S +  ++ ST   T + S+  V
Sbjct: 3724 PVTTSTEAISSSATLDSTTMSVSMPMEISTLGTTILVSTTPV 3765



 Score =  116 bits (291), Expect = 1e-25
 Identities = 233/1075 (21%), Positives = 378/1075 (35%), Gaps = 122/1075 (11%)

Query: 113  PESNTEAHVENITFYQNQEDFSTVSSKEGVMVQTSGKSHAASDAPENLTLLAETADARGR 172
            P +++EA + + T   +    +T +          G S   S   E  T L     +   
Sbjct: 3233 PVASSEASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTT 3292

Query: 173  SGSSSRTNFTILPVGYSLEIATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTAS 232
              SS  +  +  P   S  + T   + S    ++   +P+S+  + E        S + +
Sbjct: 3293 VASSETSTLSTTPADTSTPVTTYSQASSSPPIADGTSMPTST--YSEGSTPLTNMSFSTT 3350

Query: 233  EMGTERAMGLSEEWTVHSQEATTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYR 292
             + +  A  LS      S   TTS    S  P    G     S     + P  S      
Sbjct: 3351 PVVSSEASTLSTTPVDTSTPVTTST-EASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTT 3409

Query: 293  TAASSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGP 352
               SS +  LS++   +  L  ++   SSS +  +   + T  T  G   L  + +S  P
Sbjct: 3410 PVVSSEVNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTP 3469

Query: 353  VSKTEGFPKDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDE--EFIEPSTENEFGLTSL 410
            V+ +E     +    TS+ V  S     S   + VT  P     E   P T      T +
Sbjct: 3470 VASSEASTLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPV 3529

Query: 411  RWQNDSPT----FGEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTS 466
                 S         +   +SS   + SP +   T  R   P  G       LL+    S
Sbjct: 3530 ASSEASTLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLS----S 3585

Query: 467  ADVTGSSASYPEGVNASVLTQFSDSTVQSGGSHTALGDRSYSESSSTSSSESLNSSAPRG 526
              VT S AS P   +    T  + ST QS  + T     +   S+ +  S  L +  P  
Sbjct: 3586 TYVTSSEASTPSTPSVDRSTPVTTST-QSNSTPTPPEVITLPMSTPSEVSTPL-TIMPVS 3643

Query: 527  ERSIAGISYGQVRGTAIEQRTSSDHTDHTYLSSTFTKGERALLSI-TDNSSSSDIVESST 585
              S+     G      ++  TS+     T +SS+    E   + I T +  S+ +     
Sbjct: 3644 TTSVTISEAGTASTLPVD--TSTPVITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMPV 3701

Query: 586  SYIKISNSSHSEYSS-----------FFHAQTERSNISSYDGEYAQPSTESPVLHTSNLP 634
            S  ++++S  S  S+              A +  + + S     + P  E   L T+ L 
Sbjct: 3702 STTRVTSSEGSTLSTPSVVTSTPVTTSTEAISSSATLDSTTMSVSMPM-EISTLGTTILV 3760

Query: 635  SYTPTINMPNTSV--VLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSIL 692
            S TP    P +S   +          ++S  SSS ++      +P+ + S+   L +++L
Sbjct: 3761 STTPVTRFPESSTPSIPSVYTSMSMTTASEGSSSPTTLEGTTTMPMSTTSERSTLLTTVL 3820

Query: 693  -----------------PSTRASVHLLKSTSDASTPWSSSPSPLPVSLTTSTSAPLS--V 733
                             P    S  LL ST   S    +  + + +S+T+  S PL+  +
Sbjct: 3821 ISPISVMSPSEASTLSTPPGDTSTPLLTSTKAGSFSIPAEVTTIRISITSERSTPLTTLL 3880

Query: 734  SQTTLPQSSSTPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITES 793
              TTLP S      P A         TST  +  T   S+ T  +   +T     VITE 
Sbjct: 3881 VSTTLPTS-----FPGASIASTPPLDTSTTFTPSTDTASTPTIPV---ATTISVSVITEG 3932

Query: 794  KSP-SLVSLPTE-----------------STKAVTTNSPLPPSLTESSTEQTLPATSTNL 835
             +P + + +P+                  ST  +T+     PS + SST  +   T    
Sbjct: 3933 STPGTTIFIPSTPVTSSTADVFPATTGAVSTPVITSTELNTPSTSSSSTTTSFSTTK--- 3989

Query: 836  AQMSPTFTTTILKTSQPLMTTPGTLSSTASLVTGPIAVQTTAGKQLSLTHPEILVPQIST 895
                  FTT  + T+ PL  T  T+S+  S         TT+   LS T        ++T
Sbjct: 3990 -----EFTTPAMTTAAPL--TYVTMSTAPSTPRTTSRGCTTSASTLSATSTPHTSTSVTT 4042

Query: 896  EGGISTERNRVIVDATTGLIPLTSVPT-SAKEMTTKLGVTAEYSPASRSLGTSPSPQTTV 954
                 +  +      T+  IP T  P  S+   TT    T     A  ++ T   P T  
Sbjct: 4043 RPVTPSSESSRPSTITSHTIPPTFPPAHSSTPPTTSASSTTVNPEAVTTMTTRTKPSTRT 4102

Query: 955  VSTAEDLAPKSATFAVQSST---QSPTTVSSSASVNSCAVNPCLHN-GECVADNTSRGYH 1010
             S      P   T AV ++T    +PT+  +     +C  + C +    C    T  G  
Sbjct: 4103 TS-----FPTVTTTAVPTNTTIKSNPTSTPTVPRTTTCFGDGCQNTASRCKNGGTWDGLK 4157

Query: 1011 CRCPPSWQGDDCSVDVNECLSNPCPSTAMCNNTQGSFICKCPVGYQLEKGICNLVRTFVT 1070
            C+CP  + G+ C   V+     P P T               +  Q+E      +   VT
Sbjct: 4158 CQCPNLYYGELCEEVVSSIDIGP-PET---------------ISAQME------LTVTVT 4195

Query: 1071 EFKLKRTFLNTTVEKHSDLQEVENEITKTLNMCFSALPSYIRSTVHASRESNAVV 1125
              K      N       + QE +   T+ +N+ +S +P Y+   +   R  + VV
Sbjct: 4196 SVKFTEELKN---HSSQEFQEFKQTFTEQMNIVYSGIPEYVGVNITKLRLGSVVV 4247



 Score =  115 bits (288), Expect = 3e-25
 Identities = 225/954 (23%), Positives = 366/954 (38%), Gaps = 118/954 (12%)

Query: 115  SNTEAHVENITFYQNQEDFSTVSSKEGVMVQTSGKSHAASDAPENLTLLAETADARGRSG 174
            +++EA   + T        +T +          G S   S   E  T L     ++    
Sbjct: 701  ASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTLLT 760

Query: 175  SSSRTNFTILPVGYSLEIATALTSQSGNLASESLHLP-SSSSEFDERIAAFQTKSGTASE 233
            SS  +  +  P+  S  I T+  +      +E   +P S+ SE    + +      + + 
Sbjct: 761  SSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPV---SITP 817

Query: 234  MGTERAMGLSEEWTVHSQEATTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRT 293
            + +  A  LS    V S    T++   S  P    G     S       P  S       
Sbjct: 818  VTSPEASTLSTT-PVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTL 876

Query: 294  AASSPLLDLSSSSESTEK-LNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGP 352
             A+S +  LS++   T   + NST  +SS  +   T  + T     G   L S+  S  P
Sbjct: 877  VATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTS-MPTSTPGEGSTPLTSMPDSTTP 935

Query: 353  VSKTEGFPKDSRIATTSSSVLLSPSAVESRRNSRVTGNPGD--EEFIEPSTENEFGLTSL 410
            V  +E     +    TS+ V  S  A  S   +  T  P     E   P T      T +
Sbjct: 936  VVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLV 995

Query: 411  RWQNDS-----PTFGEHQLASSSEVQNGSPMSQ-----TETVSRSVAPMRGGEITAHWLL 460
                 S     P      L +S+E  +  P ++     T T S    P+    ++   + 
Sbjct: 996  ANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVA 1055

Query: 461  TNSTTSADVTGSSASYPEGVNASVLTQFSDSTVQSGGSHTALGDRSYSESS--------- 511
            ++ T++   T +  S P     +  +Q S S+  + G  T++   +YSE S         
Sbjct: 1056 SSETSTLSTTPADTSTP----VTTYSQASSSSTTADG--TSMPTSTYSEGSTPLTSVPVS 1109

Query: 512  ---------STSSSESLNSSAPRGERSIAGISYGQVRGTAIEQRTSSDHTDHTYLSSTFT 562
                     ST S+  +++S P    + A  S     GT+I     S+ T  T L+S   
Sbjct: 1110 TRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPPSEGT--TPLAS-MP 1166

Query: 563  KGERALLSITDNSSSSDIVESSTSYIKISNSSHSEYSSFFHAQTERSNISSYDGEYAQPS 622
                 ++S   N+ S+  V+S T       ++ +E SS        S  +S  GE + P 
Sbjct: 1167 VSTTLVVSSEANTLSTTPVDSKTQV-----ATSTEASSPPPTAEVTSMPTSTPGERSTPL 1221

Query: 623  TESPVLHTSNLPSYTPTINMP--NTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPS 680
            T  PV HT    S   T++    +TS  + T AE         +SSS +++ G  LP  +
Sbjct: 1222 TSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAE---------TSSSPTTAEGTSLPTST 1272

Query: 681  VSQSHHLFSSILPSTRASVH-----LLKSTSDASTPW------SSSPSP----------- 718
             S+   L +SI  ST          LL +  D   P       SSSP+P           
Sbjct: 1273 TSEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTY 1332

Query: 719  ---------LPVSLTTSTSAPLSVSQTTLPQSSSTPVLP--RARETPVTSFQTSTMTSFM 767
                     +PV+ T   S+ +S+  TT P  +STPV     A  +P TS  TS   S  
Sbjct: 1333 SEGRTPLTSIPVNTTLVASSAISILSTT-PVDNSTPVTTSTEACSSPTTSEGTSMPNSNP 1391

Query: 768  TMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLP------PSLTE 821
            +   +  T+   S +     +  T S +P   S P  +T A  T+SP        P+ T 
Sbjct: 1392 SEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPG-TTSAEATSSPTTAEGISIPTSTP 1450

Query: 822  SSTE---QTLPATSTNLAQM-SPTFTTTILKTSQPLMTTPGTLSSTASLVTGPIAVQTTA 877
            S  +   +++P ++T +A   + T +TT + ++ P++T+    SS        IA+ T +
Sbjct: 1451 SEGKTPLKSIPVSNTPVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPS 1510

Query: 878  GKQLSLTHPEILVPQISTEGGISTERNRVIVDATTGLIPLTSVPTSAKEMTTKLGV---T 934
                +LT     +P +ST    S+E N +         P+T+   ++   TT  G    T
Sbjct: 1511 EGSTALTS----IP-VSTTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQT 1565

Query: 935  AEYSPASRSLGTSPSPQTTVVSTAEDLAPKSATFAVQSSTQSPTTVSSSASVNS 988
            + YS  S  L + P     VVS+    A   +T  + S TQ   +  +S+S  +
Sbjct: 1566 STYSEGSTPLTSLPVSTMLVVSSE---ANTLSTTPIDSKTQVTASTEASSSTTA 1616



 Score =  113 bits (283), Expect = 1e-24
 Identities = 223/914 (24%), Positives = 359/914 (39%), Gaps = 120/914 (13%)

Query: 113  PESNTEAHVENITFYQNQEDFSTVSSKEGVMVQTSGKSHAASDAPENLTLLAETADARGR 172
            P +N+EA   + T   +     T ++         G S A S   E  T L     +   
Sbjct: 1466 PVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALTSIPVSTTT 1525

Query: 173  SGSSSRTNFTILPVGYSLEIATALTSQSGNLASESLHLPSSS-SEFDERIAAF--QTKSG 229
              SS   + +  P   S  + T   + S    ++   + +S+ SE    + +    T   
Sbjct: 1526 VASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLV 1585

Query: 230  TASEMGTERAMGLSEEWTVHSQEATTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLH 289
             +SE  T     +  +  V    A+T A S +      M  ++TPS       P L+ + 
Sbjct: 1586 VSSEANTLSTTPIDSKTQV---TASTEASSSTTAEGSSM-TISTPSE----GSPLLTSIP 1637

Query: 290  FYRTAASSPLLDLSSSS--ESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRT-LRSL 346
               T  +SP     S++  +S   +  ST + SS      T    + +T+G  RT L S+
Sbjct: 1638 VSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTYTEG--RTPLTSI 1695

Query: 347  TVSLGPVSKTEGFPKDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFG 406
            TV   PV+ +      +     S+ V  S  A  S   S  T  P               
Sbjct: 1696 TVRTTPVASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEGTSMP--------------- 1740

Query: 407  LTSLRWQNDSPTFGEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNST-- 464
                   N +P+ G   L S        P+S T  +S   + +    I     +T ST  
Sbjct: 1741 -------NSTPSEGTTPLTSI-------PVSTTPVLSSEASTLSATPIDTSTPVTTSTEA 1786

Query: 465  TSADVTGSSASYPEGVNASVLTQFSDSTVQSGGSHTALGDRSYSESSSTSSSESLNSSAP 524
            TS+  T    S P    +  +T  + + V    SHT + +      +ST S+  ++S++P
Sbjct: 1787 TSSPTTAEGTSIPTSTLSEGMTPLTSTPV----SHTLVAN----SEASTLSTTPVDSNSP 1838

Query: 525  RGERSIAGISYGQVRGTAIEQRTSSDHTDHTYLSSTFTKGERALLSITDNSSSSDIVESS 584
                +    S     GT+I   T S+ +  T L+S          S T+  S++  V S+
Sbjct: 1839 VVTSTAVSSSPTPAEGTSIATSTPSEGS--TALTSIPVSTTTVASSETNTLSTTPAVTST 1896

Query: 585  --TSYIKISNSSHSEYSSFFHAQTERSNISSYDGEYAQPSTESPVLHTSNLPSYTPTINM 642
              T+Y ++S+S  +   S     T R        E   P T  PV  T+   S   T++ 
Sbjct: 1897 PVTTYAQVSSSPTTADGSSMPTSTPR--------EGRPPLTSIPVSTTTVASSEINTLS- 1947

Query: 643  PNTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSILPSTRASVHLL 702
               + + DT       ++ S +SSS +++ G  +P P+ S+     +S+  ST   V   
Sbjct: 1948 ---TTLADTRTPV---TTYSQASSSPTTADGTSMPTPAYSEGSTPLTSMPLSTTLVV--- 1998

Query: 703  KSTSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQSSSTPVLPRARETPVTSFQTST 762
              +S+AST    S +P+  S   +TS   S S TT   +S     P  R TP+     ST
Sbjct: 1999 --SSEAST---LSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSERTTPLAGMPVST 2053

Query: 763  --MTSFMTMLHSSQTADLKSQSTPHQE--KVITESKSPSLVSLPTESTKAVTTN--SPLP 816
              + S      S+   D K+Q T   E     T   S   +S P+E +  +T+   S  P
Sbjct: 2054 TLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLLTSIPLSTTP 2113

Query: 817  PSLTESSTEQTLPATSTNLAQMSPTFTTTILKTSQPLMTTPGTLSSTAS-------LVTG 869
             +  E+ST  T P  S      SP  T+T + +S   + T GT   T++       L + 
Sbjct: 2114 VASPEASTLSTTPVDSN-----SPVITSTEVSSSP--IPTEGTSMQTSTYSDRRTPLTSM 2166

Query: 870  PIA---VQTTAGKQLSLTHPEILVPQI-STEGGISTERNRVIVDATT----GLIPLTSVP 921
            P++   V ++A   LS T  +   P   STE   S   +      T+    G  P TS+P
Sbjct: 2167 PVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFTSMP 2226

Query: 922  TSAKEMTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSATFAVQSSTQSPTTVS 981
             S   +     VT+E S    +L  +P   +T V+T+ + A  S T A  +S  + T   
Sbjct: 2227 VSTMPV-----VTSEAS----TLSATPVDTSTPVTTSTE-ATSSPTTAEGTSIPTSTLSE 2276

Query: 982  SSASVNSCAVNPCL 995
             +  + S  V+  L
Sbjct: 2277 GTTPLTSIPVSHTL 2290



 Score =  109 bits (273), Expect = 2e-23
 Identities = 222/933 (23%), Positives = 369/933 (39%), Gaps = 140/933 (15%)

Query: 113  PESNTEAHVENITFYQNQEDFSTVSSKEGVMVQTSGKSHAASDAPENLTLLAETADARGR 172
            P ++ EA   + T   +     T +          G S   S   E  T L         
Sbjct: 1642 PVASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTYTEGRTPLTSITVRTTP 1701

Query: 173  SGSSSRTNFTILPVGYSLEIATALTSQSGNLASESLHLPSSS-SEFDERIAAF--QTKSG 229
              SS+ +  +  PV  S  + T+  ++S    SE   +P+S+ SE    + +    T   
Sbjct: 1702 VASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPV 1761

Query: 230  TASEMGTERAMGLSEEWTVH-SQEATTSAWSP--SFLPALEMGELTTPSRKRNSSGPDLS 286
             +SE  T  A  +     V  S EAT+S  +   + +P   + E  TP      S     
Sbjct: 1762 LSSEASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVS----- 1816

Query: 287  WLHFYRTAASSPLLDLSSSS-ESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRS 345
                +   A+S    LS++  +S   +  ST + SSS +  +   +AT     G   L S
Sbjct: 1817 ----HTLVANSEASTLSTTPVDSNSPVVTSTAV-SSSPTPAEGTSIATSTPSEGSTALTS 1871

Query: 346  LTVSLGPVSKTEGFPKDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEF 405
            + VS   V+ +E     +   +T+ +V  +P    ++ +S  T   G         E   
Sbjct: 1872 IPVSTTTVASSE-----TNTLSTTPAVTSTPVTTYAQVSSSPTTADGSSMPTSTPREGRP 1926

Query: 406  GLTSLRWQNDSPTFGEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTT 465
             LTS+     +         +SSE+          T+S ++A  R   +T +   ++S T
Sbjct: 1927 PLTSIPVSTTT--------VASSEIN---------TLSTTLADTRT-PVTTYSQASSSPT 1968

Query: 466  SADVTGS-SASYPEGVNASVLTQFSDSTVQSGGSHTALGDRSYSESSSTSSSESLNSSAP 524
            +AD T   + +Y EG         S + V S  + T       + + +T+S+E  +S   
Sbjct: 1969 TADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTT 2028

Query: 525  RGERSIAGISYGQVRGTAIEQRTSSDHTDHTYLSSTFTKGERALLSITDNSSSSDIVESS 584
             G             GT+I+  T S+ T  T L+         ++S   N+ S+  V+S 
Sbjct: 2029 AG-------------GTSIQTSTPSERT--TPLAG-MPVSTTLVVSSEGNTLSTTPVDSK 2072

Query: 585  TSYIKISNSSHSEYSSFFHAQTERSNISSYDGEYAQPSTESPVLHTSNLPSYTPTINMPN 644
            T   +++NS+  E SS   A+     IS+       PS  SP+L  +++P  T  +  P 
Sbjct: 2073 T---QVTNST--EASSSATAEGSSMTISA-------PSEGSPLL--TSIPLSTTPVASPE 2118

Query: 645  TSVV----LDTDAEFVSDSSSSSS-------SSSSSSSSGPPLPLPSVSQSHHLFSSILP 693
             S +    +D+++  ++ +  SSS       S  +S+ S    PL S+  S  + +S   
Sbjct: 2119 ASTLSTTPVDSNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAI 2178

Query: 694  STRA------SVHLLKSTSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQSSSTPVL 747
            ST +      S  +  ST   S+P +S  + +P    TST +  S   T++P S+   V 
Sbjct: 2179 STLSTTPVDTSTPVTNSTEARSSPTTSEGTSMP----TSTPSEGSTPFTSMPVSTMPVVT 2234

Query: 748  PRARETPVTSFQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLP----- 802
              A     T   TST  +  T   SS T    ++ T      ++E  +P L S+P     
Sbjct: 2235 SEASTLSATPVDTSTPVTTSTEATSSPTT---AEGTSIPTSTLSEGTTP-LTSIPVSHTL 2290

Query: 803  -------TESTKAVTTNSPLPPSLTESSTEQTLPATS----------TNLAQM------- 838
                   T ST  V +N+P   S   SS   T   TS          T L +M       
Sbjct: 2291 VANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMV 2350

Query: 839  ----SPTFTTTILKTSQPLMT--TPGTLSSTASLVTGPIAVQTTAGKQLSLTHPEILVPQ 892
                + T +TT   TS P+ T    G+  +TA   + P +  +     L+ + P   +P 
Sbjct: 2351 ASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLT-SVPVSTMPV 2409

Query: 893  ISTEGGISTERNRVIVDATTGLIPLTSVPTSAKEMTTKLGVTAEYSPASRSLGTSPSPQT 952
            +S+E   ++  +   VD +T   P+T+   ++   TT  G +   SP S   GT+P    
Sbjct: 2410 VSSE---ASTHSTTPVDTST---PVTTSTEASSSPTTAEGTSIPTSPPSE--GTTPLASM 2461

Query: 953  TVVSTAEDLAPKSATFAVQSSTQSPTTVSSSAS 985
             V +T    +           T +P T S+ AS
Sbjct: 2462 PVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEAS 2494



 Score =  105 bits (263), Expect = 2e-22
 Identities = 210/976 (21%), Positives = 379/976 (38%), Gaps = 114/976 (11%)

Query: 60   PEREPPPTPPRERRGPA-TPGPSYRAPEPGAATQRGPS----GRAPRGGSADAAWKHWPE 114
            PE     T P +   P  T      +P P   T    S    GR P         +  P 
Sbjct: 1646 PEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTYTEGRTPL---TSITVRTTPV 1702

Query: 115  SNTEAHVENITFYQNQEDFSTVSSKEGVMVQTSGKSHAASDAPENLTLLAETADARGRSG 174
            +++     + T   N    +T +        + G S   S   E  T L     +     
Sbjct: 1703 ASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVL 1762

Query: 175  SSSRTNFTILPVGYSLEIATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTASEM 234
            SS  +  +  P+  S  + T+  + S    +E   +P+S+    E +    +   + + +
Sbjct: 1763 SSEASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIPTST--LSEGMTPLTSTPVSHTLV 1820

Query: 235  GTERAMGLSEEWT-VHSQEATTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRT 293
                A  LS      +S   T++A S S  PA E   + T +    S+            
Sbjct: 1821 ANSEASTLSTTPVDSNSPVVTSTAVSSSPTPA-EGTSIATSTPSEGSTA----------- 1868

Query: 294  AASSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGG------PRTLRSLT 347
              S P+   + +S  T  L+ +  + S+ V+    +  +    DG       PR  R   
Sbjct: 1869 LTSIPVSTTTVASSETNTLSTTPAVTSTPVTTYAQVSSSPTTADGSSMPTSTPREGRPPL 1928

Query: 348  VSLGPVSKTEGFPKDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGL 407
             S+ PVS T     +    +T+ +   +P    S+ +S  T   G        +E    L
Sbjct: 1929 TSI-PVSTTTVASSEINTLSTTLADTRTPVTTYSQASSSPTTADGTSMPTPAYSEGSTPL 1987

Query: 408  TSLRWQNDSPTFGEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSA 467
            TS+          E    S++ V   +P + +   S S     G  I        ++T +
Sbjct: 1988 TSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSI-------QTSTPS 2040

Query: 468  DVTGSSASYPEGVNASVLTQFSDSTVQSGGSHTALGDRSYSESSSTSSSESLNSSAPRGE 527
            + T   A  P      V ++ +  +     S T + + + + SS+T+   S+  SAP   
Sbjct: 2041 ERTTPLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAP--- 2097

Query: 528  RSIAGISYGQVRGTAIEQRTSSDHT-DHTYLSSTFTKGERALLSITDNSSS-----SDIV 581
                  S G    T+I   T+   + + + LS+T       +++ T+ SSS        +
Sbjct: 2098 ------SEGSPLLTSIPLSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPIPTEGTSM 2151

Query: 582  ESSTSYIKISNSSHSEYSSFFHAQTERSNISSYDGEYAQPSTESPVLHTS-------NLP 634
            ++ST   + +  +    S+   A +  S +S+   + + P T S    +S       ++P
Sbjct: 2152 QTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMP 2211

Query: 635  SYTPTI-NMPNTSVVLDTDAEFVSDSS---------------SSSSSSSSSSSSGPPLPL 678
            + TP+  + P TS+ + T     S++S               S+ ++SS +++ G  +P 
Sbjct: 2212 TSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPT 2271

Query: 679  PSVSQSHHLFSSILPSTRASVHLLKSTSDASTPWSSSPSPLPVSLTTSTSA---PLSVSQ 735
             ++S+     +SI  S     H L + S+ ST  S++P       TTST A   P +   
Sbjct: 2272 STLSEGTTPLTSIPVS-----HTLVANSEVST-LSTTPVDSNTPFTTSTEASSPPPTAEG 2325

Query: 736  TTLPQSSSTPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKS 795
            T++P S+S+        TP+T    ST     TM+ S +T+ L +        V T S++
Sbjct: 2326 TSMPTSTSSE-----GNTPLTRMPVST-----TMVASFETSTLSTTPADTSTPVTTYSQA 2375

Query: 796  PSLVSLPTESTKAVTTNSPLPPSLTESSTEQTLPATSTNLAQMS--PTFTTTILKTSQPL 853
             S  +   +++   +T S     LT S    T+P  S+  +  S  P  T+T + TS   
Sbjct: 2376 GSSPTTADDTSMPTSTYSEGSTPLT-SVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEA 2434

Query: 854  MTTPGTLSSTASLVTGPIAVQTTAGKQLSLTHPEILVPQISTEGGISTERNRVIVDATTG 913
             ++P T   T S+ T P +  TT         P   +P +ST   +S+E   +       
Sbjct: 2435 SSSPTTAEGT-SIPTSPPSEGTT---------PLASMP-VSTTPVVSSEAGTLSTTPVDT 2483

Query: 914  LIPLT------SVPTSAKEMTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSAT 967
              P+T      S PT+A+++   +   +E S    S+  S +P  +  ++     P  + 
Sbjct: 2484 STPMTTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPEASTLSTTPVDSN 2543

Query: 968  FAVQSSTQSPTTVSSS 983
              V +ST+  ++ +S+
Sbjct: 2544 SPVVTSTEISSSATSA 2559



 Score =  103 bits (257), Expect = 1e-21
 Identities = 239/1064 (22%), Positives = 386/1064 (36%), Gaps = 136/1064 (12%)

Query: 24   PPAAPGTRDPPPSPARRALSLAPLAGAGLELQLERRPEREPPPTPPRERRGPATPGPSYR 83
            P  A GT  P  +P  R     PL    +        E       P +   P T      
Sbjct: 2969 PTTAEGTSMPISTPGERR---TPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTE-A 3024

Query: 84   APEPGAATQRGPSGRAPRGGSADAAW---KHWPESNTEAHVENITFYQNQEDFSTVSSKE 140
            +  P  A   G     P  GS           P +  EA   + T   +     T +   
Sbjct: 3025 SSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVS 3084

Query: 141  GVMVQTSGKSHAASDAPENLTLLAETADARGRSGSSSRTNFTILPVGYSLEIATALTSQS 200
                   G S   S   E  T L     +     SS+ +  +  PV  S  + T+  + S
Sbjct: 3085 SSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTSTEAHS 3144

Query: 201  GNLASESLHLPSSS-------------------SEFDERIAAFQTKSGTASEMGTERAMG 241
                SE   +P+S+                   S  D  ++A    + T     TE    
Sbjct: 3145 SPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSS 3204

Query: 242  LSEEWTVHSQEATTSAWSPSFLPALEMGELTTPSRKRNSS------GPDLSWLHFYRTAA 295
             + E T       TS  S    P   +    TP     +S          + L     A+
Sbjct: 3205 TTAEGT----SIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEAS 3260

Query: 296  SSPLLDLSSSSESTEKLNNSTGLQSSSVSQT-----KTMHVATVFTDGG-PRTLRSLTVS 349
            SSP     +S  ++     ST L S  VS T     +T  ++T   D   P T  S   S
Sbjct: 3261 SSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQASS 3320

Query: 350  LGPVSKTEGFPKD--SRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEF-IEPSTENEFG 406
              P++     P    S  +T  +++  S + V S   S ++  P D    +  STE    
Sbjct: 3321 SPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTSTEASLS 3380

Query: 407  LTSLRWQN---DSPTFGEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNS 463
             T+    +    SP+ G   LAS        P+S T  VS  V  +    + ++ L+T S
Sbjct: 3381 PTTAEGTSIPTSSPSEGTTPLASM-------PVSTTPVVSSEVNTLSTTPVDSNTLVTTS 3433

Query: 464  TTSADVTGSSASYPEGVNASVLTQFSDSTVQSGGSHTALGDRSY----SESSSTSSSESL 519
            T ++    SS +  EG      T    ST   G +  ++   S     S  +ST S+  +
Sbjct: 3434 TEAS----SSPTIAEG------TSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTPV 3483

Query: 520  NSSAPRGERSIAGISYGQVRGTAIEQRTSSDH----TDHTYLSSTFTKGERALLSITDNS 575
            ++S P    S    S      T++   T+ +     T+    ++     E + LS T   
Sbjct: 3484 DTSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVD 3543

Query: 576  S-----SSDIVESSTSYIKISNSSHSEYSSFFHAQTERSNISSY--DGEYAQPSTES--- 625
            S     SS    SS + ++++    S  S    + T     S+Y    E + PST S   
Sbjct: 3544 SNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDR 3603

Query: 626  --PVLHTSNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQ 683
              PV  TS   + TPT   P   + L            S+ S  S+  +  P+   SV+ 
Sbjct: 3604 STPVT-TSTQSNSTPT---PPEVITLPM----------STPSEVSTPLTIMPVSTTSVTI 3649

Query: 684  SHHLFSSILPSTRASVHLLKSTSDASTPWSSSPSPLPV-----SLTTSTSAPLSVSQTTL 738
            S    +S LP    S  ++ ST  +S+P +   + +P+       T  T+ P+S ++ T 
Sbjct: 3650 SEAGTASTLP-VDTSTPVITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMPVSTTRVTS 3708

Query: 739  PQSSSTPVLPRARETPVTS----------FQTSTMTSFMTMLHSSQTADLKSQSTPHQEK 788
             + S+         TPVT+            ++TM+  M M  S+    +   +TP    
Sbjct: 3709 SEGSTLSTPSVVTSTPVTTSTEAISSSATLDSTTMSVSMPMEISTLGTTILVSTTPVTR- 3767

Query: 789  VITESKSPSLVSLPTESTKAVTTNSPLPPSLTESSTEQTLPATSTNLAQMSPTFTTTILK 848
               ES +PS+ S+ T  +    +     P+  E +T   +  TS        T  TT+L 
Sbjct: 3768 -FPESSTPSIPSVYTSMSMTTASEGSSSPTTLEGTTTMPMSTTSER-----STLLTTVLI 3821

Query: 849  TSQPLMTTP--GTLSSTASLVTGPIAVQTTAGKQLSLTHP-EILVPQISTEGGISTERNR 905
            +   +M+     TLS+     + P+   T AG   S + P E+   +IS     ST    
Sbjct: 3822 SPISVMSPSEASTLSTPPGDTSTPLLTSTKAG---SFSIPAEVTTIRISITSERSTPLTT 3878

Query: 906  VIVDATTGLIPLTSVPTSAKEMTTKLGVTAEYSPASRSLGTSPSPQTTVVSTA---EDLA 962
            ++V  T   +P TS P ++   T  L  +  ++P++ +  T   P  T +S +   E   
Sbjct: 3879 LLVSTT---LP-TSFPGASIASTPPLDTSTTFTPSTDTASTPTIPVATTISVSVITEGST 3934

Query: 963  PKSATFAVQSSTQSPTTVSSSASVNSCAVNPCLHNGECVADNTS 1006
            P +  F + S+  + +T     +       P + + E    +TS
Sbjct: 3935 PGTTIF-IPSTPVTSSTADVFPATTGAVSTPVITSTELNTPSTS 3977



 Score = 97.1 bits (240), Expect = 1e-19
 Identities = 194/908 (21%), Positives = 335/908 (36%), Gaps = 98/908 (10%)

Query: 24   PPAAPGTRDPPPSPARRALSLAPLAGAGLELQLERRPEREPPPTPPRERRGPATPGPSYR 83
            PP A GT  P  +P+  +    PL    +        E     T P +   P T      
Sbjct: 3263 PPTAEGTSMPTSTPSEGS---TPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQAS 3319

Query: 84   APEPGAATQRGPSGRAPRGGS--ADAAWKHWPESNTEAHVENITFYQNQEDFSTVSSKEG 141
            +  P A     P+     G +   + ++   P  ++EA   + T        +T +    
Sbjct: 3320 SSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTSTEASL 3379

Query: 142  VMVQTSGKSHAASDAPENLTLLAETADARGRSGSSSRTNFTILPVGYSLEIATALTSQSG 201
                  G S   S   E  T LA    +     SS     +  PV  +  + T+  + S 
Sbjct: 3380 SPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPVDSNTLVTTSTEASSS 3439

Query: 202  NLASESLHLPSSSSEFDERIAAFQTKSGTASEMGTERAMGLSEEWTVHSQEATTSAWSPS 261
               +E   LP+S++       +    S T   + +  A  LS      S   TTS+ + S
Sbjct: 3440 PTIAEGTSLPTSTTSEGSTPLSIMPLSTTP--VASSEASTLSTTPVDTSTPVTTSSPTNS 3497

Query: 262  FLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASSPLLDLSSSSESTEKLNNSTGLQSS 321
                 E+  + T +    S+             +++P+    +S+ ST  ++++T + SS
Sbjct: 3498 SPTTAEVTSMPTSTAGEGSTPLT------NMPVSTTPVASSEASTLSTTPVDSNTFVTSS 3551

Query: 322  SVSQTK--TMHVATVFTDGGPRTLRSLTVSLGPVSKTEGFPKDSRIATTSSSVLLSPSAV 379
            S + +   T+ V T+          SLT  L  +S T     ++   +T S    +P   
Sbjct: 3552 SQASSSPATLQVTTMRMSTPSEGSSSLTTML--LSSTYVTSSEASTPSTPSVDRSTPVTT 3609

Query: 380  ESRRNSRVTGNPGDEEFIEPSTENEFG--LTSLRWQNDSPTFGEHQLASSSEVQNGSPMS 437
             ++ NS  T  P +   +  ST +E    LT +     S T  E   AS+  V   +P+ 
Sbjct: 3610 STQSNS--TPTPPEVITLPMSTPSEVSTPLTIMPVSTTSVTISEAGTASTLPVDTSTPVI 3667

Query: 438  QTETVSRSVAPMRG----------GEITAHWLLTNSTTSADVTGSSASYPEGVNASVLTQ 487
             +  VS S     G          G      +  ++T      GS+ S P  V ++ +T 
Sbjct: 3668 TSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTPSVVTSTPVTT 3727

Query: 488  FSDSTVQSGGSHTALGDRSYSESSSTSSSESLNSSAP------RGERSIAGISYGQVRGT 541
             +++   S    +     S     ST  +  L S+ P          SI  +       T
Sbjct: 3728 STEAISSSATLDSTTMSVSMPMEISTLGTTILVSTTPVTRFPESSTPSIPSVYTSMSMTT 3787

Query: 542  AIEQRTSSDHTDHTYLSSTFTKGERALLSITDNSSSSDIVESS-----------TSYIKI 590
            A E  +S    + T      T  ER+ L  T   S   ++  S           TS   +
Sbjct: 3788 ASEGSSSPTTLEGTTTMPMSTTSERSTLLTTVLISPISVMSPSEASTLSTPPGDTSTPLL 3847

Query: 591  SNSSHSEYSSFFHAQTERSNISSYDGEYAQPSTESPVLHTSNLPSYTPTINMPNTSVVLD 650
            +++    +S      T R +I+S   E + P T   +L ++ LP+  P  ++ +T   LD
Sbjct: 3848 TSTKAGSFSIPAEVTTIRISITS---ERSTPLTT--LLVSTTLPTSFPGASIASTPP-LD 3901

Query: 651  TDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSILPSTRA---SVHLLKSTSD 707
            T   F         + S+ ++S P +P+ +      +     P T     S  +  ST+D
Sbjct: 3902 TSTTF---------TPSTDTASTPTIPVATTISVSVITEGSTPGTTIFIPSTPVTSSTAD 3952

Query: 708  ASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQSSSTPVLPRARETPVTSFQTSTMTSFM 767
               P ++     PV  +T  + P + S +T    S+T      +E    +  T+   +++
Sbjct: 3953 VF-PATTGAVSTPVITSTELNTPSTSSSSTTTSFSTT------KEFTTPAMTTAAPLTYV 4005

Query: 768  TMLHSSQT------------ADLKSQSTPHQEKVIT--------ESKSPSLVSLPTESTK 807
            TM  +  T            + L + STPH    +T        ES  PS ++  T    
Sbjct: 4006 TMSTAPSTPRTTSRGCTTSASTLSATSTPHTSTSVTTRPVTPSSESSRPSTITSHTIPPT 4065

Query: 808  AVTTNSPLPPSLTESSTEQTLPATSTNLAQMSPTFTTTILKTSQPLMTTPGTLSSTASLV 867
                +S  PP+ + SST     A +T   +  P+  T    TS P +TT    ++T ++ 
Sbjct: 4066 FPPAHSSTPPTTSASSTTVNPEAVTTMTTRTKPSTRT----TSFPTVTTTAVPTNT-TIK 4120

Query: 868  TGPIAVQT 875
            + P +  T
Sbjct: 4121 SNPTSTPT 4128



 Score = 96.3 bits (238), Expect = 2e-19
 Identities = 190/815 (23%), Positives = 325/815 (39%), Gaps = 86/815 (10%)

Query: 222 AAFQTKSGTASEMGTERAMGLSEEWTVHSQEATTSAWSPSFLPALEMGELTTPSRKRNSS 281
           +A  T +GT S    E  M LS           +S  S +  P +    +T P+  R +S
Sbjct: 63  SAANTATGTTSTNVVEPRMYLSCSTNPEMTSIESSVTSDT--PGVSSTRMT-PTESRTTS 119

Query: 282 GPDLSWLHFYRTAASSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGP- 340
                      T+ S+ L   S+   S+      T +  S+ S+ +++     F    P 
Sbjct: 120 ES---------TSDSTTLFPSSTEDTSSPTTPEGTDVPMSTPSE-ESISSTMAFVSTAPL 169

Query: 341 ---RTLRSLTVSLGPVSKTEGFPKDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFI 397
                  SLT  +   +      + S   TT  S  + P +  S  ++ +T  P     +
Sbjct: 170 PSFEAYTSLTYKVDMSTPLTTSTQASSSPTTPESTTI-PKSTNSEGSTPLTSMPAST--M 226

Query: 398 EPSTENEFGLTSLRWQNDSPTFGEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAH 457
           + ++     L +   +  +P     Q +SS     G  +S +       AP  G      
Sbjct: 227 KVASSEAITLLTTPVEISTPVTISAQASSSPTTAEGPSLSNS-------APSGGSTPLTR 279

Query: 458 WLLTNSTTSADVTGSSASYPEGVNASVLTQFSDSTVQSGGSHTALGDRSYSESS----ST 513
             L+     +    + ++ P   N  V+T    S+  +    T++   +Y+E S    ST
Sbjct: 280 MPLSVMLVVSSEASTLSTTPAATNIPVITSTEASSSPTTAEGTSIPTSTYTEGSTPLTST 339

Query: 514 SSSESLNSSAPRGERSIAGISYGQVRGTAIEQRTSSDHTDHT-YLSSTFTKGERALLSIT 572
            +S    +++     SI  +    +  T+ E  +     + T  L+ST ++G   L ++ 
Sbjct: 340 PASTMPVATSEMSTLSITPVDTSTLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTNMP 399

Query: 573 DNS---SSSDIVESSTSYI--KISNSSHSEYSSFFHAQTERSNISSYDGEYAQPSTESPV 627
            ++   +SS+   +ST  +  K   ++ SE SS      + S  +S   E + P T  PV
Sbjct: 400 VSTILVASSEASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPV 459

Query: 628 LHT-------SNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPS 680
             T       SNL S TP  +   T V   T+A     ++  +S  +S+ S G   PL S
Sbjct: 460 STTPVASSEASNL-STTPVDS--KTQVTTSTEASSSPPTAEVNSMPTSTPSEGST-PLTS 515

Query: 681 VSQSHHLFSSILPSTRASVHLLKST--SDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTL 738
           +S S    +S   ST ++  +  ST  + +S   SSS +P   S+ TST +  S   T +
Sbjct: 516 MSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNM 575

Query: 739 PQSSSTPVLPRARETPVTSFQTST-MTSFMTMLHSSQTADLKSQSTPHQEK----VITES 793
           P S+   V   A  T  T   ++T +T+      SS TA+  S  T    +    + + S
Sbjct: 576 PVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMS 635

Query: 794 KSPSLVSLPTESTKAVT-TNSPLPPSLTESSTEQTLPATSTNLAQMSPTFTTTILKTSQP 852
            S +LV+    ST + T  +S  P + +  +T  +  A  T++   + T  +T L TS P
Sbjct: 636 VSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPL-TSMP 694

Query: 853 LMTTPGTLSSTASLVTGPIAVQTTAGKQLSLTHPEILVPQISTEGGISTERNRVIVDATT 912
           + TT    S  ++L T P+   T          P     + S+    +   +      + 
Sbjct: 695 VNTTLVASSEASTLSTTPVDTST----------PVTTSTEASSSPTTADGASMPTSTPSE 744

Query: 913 GLIPLTSVPTSAKEMTTKLGVTAEYSP------ASRSLGTSPSPQTT-----VVSTAEDL 961
           G  PLTS+P S   +T+    T   +P       + S   S SP TT      +ST  + 
Sbjct: 745 GSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEG 804

Query: 962 APKSATFAV--------QSSTQSPTTVSSSASVNS 988
           +P   +  V        ++ST S T V S++ V +
Sbjct: 805 SPLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTT 839


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score =  119 bits (298), Expect = 2e-26
 Identities = 256/1073 (23%), Positives = 406/1073 (37%), Gaps = 176/1073 (16%)

Query: 66   PTPPRERRGPATPGPSYRAPEPGAATQRGPSGRAPRGGSADAAWKHW-PESN--TEAHVE 122
            P+PP     P     +Y        T   P+     G S  +   H  P+++  T +   
Sbjct: 2231 PSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAH 2290

Query: 123  NITFYQNQEDFSTVS------------------SKEGVMVQTSGKSHAASDAPENLTLLA 164
            + T  + +   S +S                  S+      +S +S   + +P ++T L 
Sbjct: 2291 STTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLG 2350

Query: 165  ---ETADARGRSGSSSRTNFTILPV-----GYSLEIATALTSQSGNLASESL-HLPSSSS 215
               E+  +R + GS   T+ T+ P      G S E  T  +S  G+  +      P++S 
Sbjct: 2351 VGEESTTSRSQPGS---THSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRTPTTSV 2407

Query: 216  EFDERIAAFQTKSGTASEMGTERAM--GLSEEWTVH-SQEATTSAWSPSFLPALEMGELT 272
              +E        + T + + TE +   GL+EE T      A+T    P+ L   ++GE +
Sbjct: 2408 RGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEES 2467

Query: 273  TPSRKRNSSGPDLSWLHFYRTAASSPLLD-----LSSSSESTEKL----------NNSTG 317
            T     +SSG   + L   R+  S  + +     LS SS  T  L            ST 
Sbjct: 2468 TTFP--SSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTT 2525

Query: 318  LQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVSKTEGFPKD------SRIATTSSS 371
              +S  S   T+  AT  T  G     S + S    + T  FP        SR +TTS S
Sbjct: 2526 FYTSPRSPDATLSPATT-TSSGVSEESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHS 2584

Query: 372  VLLSPSAVESRR--NSRVTGNPGDEEFIEPSTENEF-------GLTSLRWQNDSPTF--- 419
               SP + ++     S  T  P  E     S+             T+L +  +S TF   
Sbjct: 2585 ---SPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSS 2641

Query: 420  ----------------GEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEIT--AHWLLT 461
                            G  + ++      GSP +     S +   ++G   T   H   T
Sbjct: 2642 PGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTTFQTHPAST 2701

Query: 462  NSTTSADVTGS-----SASYPEGVNASVLTQFSDSTVQSGGSHTALGDRSYSESSSTSSS 516
            ++T S   T +     S +Y     ++  T F  S+  SG S  +    S  ++S T+ S
Sbjct: 2702 HTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPS 2761

Query: 517  ESLNSSAPRGERSIAGISYGQVRGTAIEQRTSSDHTDHTYLSSTFTKGERALLSITDNSS 576
             + ++++ RGE + + IS G    T +   T++        S+TF    R+  +    +S
Sbjct: 2762 SAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEA--STTFYSSPRSPTTTLSPAS 2819

Query: 577  --SSDIVESSTSYIKISNSSHSEYSSFFHAQTERSNISSYDGEYAQPSTESPVLHTSNLP 634
              S  + E ST+      S+HS  S         S  S+     +  STE+ V   S   
Sbjct: 2820 MTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTT 2879

Query: 635  S---------YTPTINMPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSH 685
            S         ++   +   T    D+    +++ S++   S +S+ +G P  L +     
Sbjct: 2880 SVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGE 2939

Query: 686  HLFSSILPSTRASVHLLKSTSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQSSSTP 745
               S+  PS+        ST    +P  S+ S L    T S  +P S   TTLP S +TP
Sbjct: 2940 E--STTFPSSSG------STGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTP 2991

Query: 746  VLPRARETPVTSFQTSTMTSFMTMLHSSQTADLKSQ--STPHQEKVITESKSPSLVSLPT 803
             L        T+F TS  +   T+  ++ T+   S+  ST H +   T +      + P 
Sbjct: 2992 SLSEKS----TTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHT-----TAFPD 3042

Query: 804  ESTKAVTTNSPLPPSLTESSTEQTL---PATSTNLAQMSPTF-------TTTILK----T 849
             +T +  +  P     ++ STE TL     T+++L Q S TF        TT+L     T
Sbjct: 3043 STTTSGLSQEPTASHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTIT 3102

Query: 850  SQPLMTTPGTLSSTASL-VTGPIAVQTTAG-KQLSLTHPEILVPQISTEGGISTERNRVI 907
            S  +  +  T SST SL  T   A  T+AG ++ S T         +T     T    V 
Sbjct: 3103 SGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVE 3162

Query: 908  VDATTGLIPLTSVPTSAKEMTTKLGVTAEYSPASRSLG---------------------T 946
            V  T    P ++  T     +T LG + E +    S G                     T
Sbjct: 3163 VSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTT 3222

Query: 947  SP----SPQTTVV---STAEDLAPKSATFAVQSSTQSPTTVSSSASVNSCAVN 992
            SP    S +TT +   +T   L+ KS TF   SS +SP T  S AS  S  V+
Sbjct: 3223 SPISSGSTETTALPGSTTTAGLSEKSTTF--YSSPRSPDTTLSPASTTSSGVS 3273



 Score =  119 bits (298), Expect = 2e-26
 Identities = 247/1016 (24%), Positives = 392/1016 (38%), Gaps = 145/1016 (14%)

Query: 91   TQRGPSGRAPRGGSADAAWKHWPESN---------TEAHVENITFYQNQED------FST 135
            T   P+G   R G +   ++ WP S          T A VE  T             FS 
Sbjct: 3372 TTLSPAGSTTRQGES-TTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSA 3430

Query: 136  VS-----SKEGVMVQTSGKSHAASDAPENLT---LLAETADARGRSGSSSRTNF--TILP 185
             S     S+E   V +S  + A + +P   T   L+ E+       GS+   +F  +   
Sbjct: 3431 SSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESDTT 3490

Query: 186  VGYSLEIATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTASEM---GTERAMGL 242
             G   E  T+ +S +  ++S     PS++S   E   ++ +  G+ +      +    G 
Sbjct: 3491 SGRGEESTTSHSSTTHTISSA----PSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGR 3546

Query: 243  SEEWTVH--SQEATTSAWSP-----------SFLPALEMGELTTPSRKRNSSGPDLSWLH 289
            SEE T    SQ+AT +   P           S    +  G + T +   +++ P LS   
Sbjct: 3547 SEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKS 3606

Query: 290  F-YRTAASSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGG--PRTLRSL 346
              + ++  SP   LS +S ++  ++  +    S    T T    T F D    P   R  
Sbjct: 3607 TTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHT----TAFPDSTTTPGLSRHS 3662

Query: 347  TVSLGPVSKTEG--FPKDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPST--E 402
            T S      T+    P  +  + +S     S S+  S   +   G+     F + ST   
Sbjct: 3663 TTSHSSPGSTDTTLLPASTTTSGSSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFH 3722

Query: 403  NEFGLTSLRWQNDSPTF-GEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITA---HW 458
            +  G T      DS T  G  + ++      GSP +     S S +P   GE TA   H 
Sbjct: 3723 SSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPAS-STSPGLQGESTAFQTHP 3781

Query: 459  LLTNSTTSADVTGS-----SASYPEGVNASVLTQFSDSTVQSGGSHTALGDRSYSESSST 513
              T++T S   T +     S +Y     ++  T F  S+  SG S  +    S  ++S T
Sbjct: 3782 ASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGT 3841

Query: 514  SSSESLNSSAPRGERSIAGISYGQVRGTAIEQRTSSDHTDHTYLSSTFTKGERALLSITD 573
            + S + ++++ RGE + + IS G    T +   T++        S+TF    R+  +   
Sbjct: 3842 TPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEA--STTFYSSPRSPTTTLS 3899

Query: 574  NSS--SSDIVESSTSYIKISNSSHSEYSSFFHAQTERSNISSYDGEYAQPSTESPVLHTS 631
             +S  S  + E ST+      S+HS  S         S  S+     +  STE+ V   S
Sbjct: 3900 PASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRS 3959

Query: 632  NLPS---------YTPTINMPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVS 682
               S         ++   +   T    D+    +++ S++   S +S+ +G P  L +  
Sbjct: 3960 TTTSVRREEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTAD 4019

Query: 683  QSHHLFSSILPSTRASVHLLKSTSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQSS 742
                  S+  PS+  S      T    +P  S+ S L    T S  +P S   TTLP S 
Sbjct: 4020 LGEE--STTFPSSSGS------TGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSP 4071

Query: 743  STPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADLKSQ--STPHQEKVITESKSPSLVS 800
            +TP L        T+F TS  +   T+  ++ T+   S+  ST H +   T +      +
Sbjct: 4072 TTPSLSEKS----TTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHT-----TA 4122

Query: 801  LPTESTKAVTTNSPLPPSLTESSTEQTL---PATSTNLAQMSPTF-------TTTILK-- 848
             P  +T +  +  P     ++ STE TL     T+++L Q S TF        TT+L   
Sbjct: 4123 FPDSTTTSGLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDD 4182

Query: 849  --TSQPLMTTPGTLSSTASLVT--GPIAVQTTAGKQLSLTHPEILVPQISTEGGISTERN 904
              TS  +  +  T SST SL T   P +  +T  ++ S T         +T    ST   
Sbjct: 4183 TITSGLVEASTPTHSSTGSLHTTLTPASSTSTGLQEESTTFQSWPSSSDTTPSPPSTTAV 4242

Query: 905  RVIVDATTGLIPLTSVPTSAKEMTTKLGVTAEYSPASRSLG------------------- 945
             V V  T    P ++  T     +T LG + E +    S G                   
Sbjct: 4243 PVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGE 4302

Query: 946  --TSP----SPQTTVV---STAEDLAPKSATFAVQSSTQSPTTVSSSASVNSCAVN 992
              TSP    S +TT +   +T   L+ KS TF   SS +SP T  S AS  S  V+
Sbjct: 4303 PTTSPISSGSTETTALPGSTTTAGLSEKSTTF--YSSPRSPDTTLSPASTTSSGVS 4356



 Score =  117 bits (292), Expect = 1e-25
 Identities = 234/992 (23%), Positives = 386/992 (38%), Gaps = 156/992 (15%)

Query: 113  PESNTEAHVENITFYQNQEDFSTVSSKEGVMVQTSGKSHAASDAPENLTLLAETADARGR 172
            P S T   VE  T Y ++   ST ++       T G+S       E  T +  +  A G 
Sbjct: 4236 PPSTTAVPVEVSTTYHSRPS-STPTTHFSASSTTLGRS-------EESTTVHSSPGATGT 4287

Query: 173  SGSSSRTNFTIL-------PVGYSLEIATAL--TSQSGNLASESLHLPSSSSEFDERIA- 222
            +   +R+  ++L       P+       TAL  ++ +  L+ +S    SS    D  ++ 
Sbjct: 4288 ALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSP 4347

Query: 223  AFQTKSGTASEMGTERAMGLSEEWTVH---------SQEATTSAWSPSFLPALEMGELTT 273
            A  T SG + E  T  +   S   T           SQE+T S  SP          L+ 
Sbjct: 4348 ASTTSSGVSEESTTSHSRPGSMHTTAFPSSTTMPGVSQESTASHSSPGSTDTT----LSP 4403

Query: 274  PSRKRNSSGPDLSWLHFYRTAASSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVAT 333
             S   +S GP+ +  H    +  + LL  ++++     L  ST + SS+ S   T+  A 
Sbjct: 4404 GSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGL--LEASTPVHSSTGSPHTTLSPAG 4461

Query: 334  VFTDGGPRTL-----RSLTVSLGPVSKTEGFPKDSRIATTSSSVLLSPSAVESRRNSRVT 388
              T  G  T       S   +  P + T  F +   ++TTS     SPS+  +   S  +
Sbjct: 4462 STTRQGESTTFQSWPNSKDTTPAPPTTTSAFVE---LSTTSHG---SPSSTPTTHFSASS 4515

Query: 389  GNPGDEEFIEPSTENEFGLTSLRWQNDSPTFGEHQLASSSEVQNGSPMSQTETV---SRS 445
               G  E       +     +      S T G   L   S   + SP S T+T+     +
Sbjct: 4516 TTLGRSEESTTVHSSPVATATTPSPARSTTSG---LVEESTTYHSSPGS-TQTMHFPESN 4571

Query: 446  VAPMRGGE-ITAHWLLTNSTTSADVTGSS-----ASYPEGVNASVLTQFSDSTVQSGGSH 499
                RG E  T+H   T++ +SA  T S+      SY     ++  T F DS+  SG S 
Sbjct: 4572 TTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSE 4631

Query: 500  TALGDRSYSESSSTSSSESLNS-SAPRGERSIAGISYGQVRGTAIEQRTSSDHTDHTYLS 558
             +    S  +++ T    + ++ S   GE + + IS G +  TA+   T++        S
Sbjct: 4632 ESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEK--S 4689

Query: 559  STFTKGERALLSITDNSSSSDIVESSTSYIKISNSSHSEYSSFFHAQTERSNISSYDGEY 618
            +TF          + +S+ +    +S++ +  S  S + +SS     T  S   S     
Sbjct: 4690 TTFHS--------SPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGL 4741

Query: 619  AQPSTESPVLHTSNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPL 678
             + ST     H+S  P  T T++ P +S      A   S+ S +S SS++ + S PP   
Sbjct: 4742 VEEST---AYHSS--PGSTQTMHFPESST-----ASGRSEESRTSHSSTTHTISSPPSTT 4791

Query: 679  PSVSQSHHLFSSILPSTRASVHLLKST-----SDASTPWSSSP-----SPLPVSLTTSTS 728
             ++ +    + S  P + A+ H  +S+     S+ ST   SSP     +PLP   TTS  
Sbjct: 4792 SALVEEPTSYHSS-PGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGR 4850

Query: 729  APLSVS--------QTTLPQSSSTPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADLKS 780
               S +        +TTL  +++TP L        T   +S+ +   T+  +S T+   S
Sbjct: 4851 IAESTTFYISPGSMETTLASTATTPGL----SAKSTILYSSSRSPDQTLSPASMTS---S 4903

Query: 781  QSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESSTEQTLPATSTNLAQMSP 840
              +     + ++++S    + P  +T +  +           STE TL   S   +  + 
Sbjct: 4904 SISGEPTSLYSQAESTHTTAFPASTTTSGLSQESTTFHSKPGSTETTLSPGSITTSSFAQ 4963

Query: 841  TFTT------TILKTSQPLMTT-PGTLSSTASLVTGPIAVQTTAGKQLSLTHPEILVPQI 893
             FTT      + L T  P  TT PG    + +  + P + +TTA      +H   +    
Sbjct: 4964 EFTTPHSQPGSALSTVSPASTTVPGLSEESTTFYSSPGSTETTA-----FSHSNTM---- 5014

Query: 894  STEGGISTERNRVIVDA---TTGLIPLTSVPTSAKEMTTKLGVTAEYSPASRSLGTSPSP 950
                 I ++++    D+   T  ++P T   T   + +T       +  +S + GT+P P
Sbjct: 5015 ----SIHSQQSTPFPDSPGFTHTVLPATLTTTDIGQESTA------FHSSSDATGTTPLP 5064

Query: 951  QTTVVSTAEDLAPKSATFAVQSS----------------TQSPTTVSSSASVNSCAVNP- 993
                 STA DL  +  TF +  S                T+  TT  +S S  S  V+  
Sbjct: 5065 AR---STASDLVGEPTTFYISPSPTYTTLFPASSSTSGLTEESTTFHTSPSFTSTIVSTE 5121

Query: 994  ---CLHNGECVADNTSRGYHCRCPPSWQGDDC 1022
                L  G C       G  C CP  + G  C
Sbjct: 5122 SLETLAPGLCQEGQIWNGKQCVCPQGYVGYQC 5153



 Score =  110 bits (274), Expect = 1e-23
 Identities = 222/985 (22%), Positives = 358/985 (36%), Gaps = 156/985 (15%)

Query: 78   PGPSYRAPEPGAATQRGPSGRAPRG----GSADAAWKHWPESNTEAHVENITFYQNQEDF 133
            PG ++    PG+ T  G S  +       GS D        + +    E+ TF+ +    
Sbjct: 1726 PGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGST 1785

Query: 134  STVSSKEGV----MVQTSGKSHAASDAPENLTLLAETADARGRSGS-----SSRTNFTIL 184
             T    +      +++ S   H+++ +P      A +   +G S +     SS+      
Sbjct: 1786 ETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAP 1845

Query: 185  PVGYSLEIATALTSQSGNLASESLHLPSSS-----SEFDERIAAFQTKSGTASEMGTERA 239
            P   S  +  + TS     ++ + H  +SS     SE    + +    + T         
Sbjct: 1846 PTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTT 1905

Query: 240  MGLSEEWTVHSQEATTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASSPL 299
             GL EE T +         SP     +   E +T S +   S          RT+ SS  
Sbjct: 1906 SGLVEESTAYHS-------SPGSTQTMHFPESSTASGRSEES----------RTSHSSTT 1948

Query: 300  LDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVSKTEGF 359
              +SS   +T  L        SS   T T H     T  G     + + S    + T   
Sbjct: 1949 HTISSPPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVL 2008

Query: 360  PKDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQNDSPTF 419
            P     A +++SVLL  S                     P +      T+L     +P  
Sbjct: 2009 P-----ARSTTSVLLGESTTS------------------PISSGSMETTALPGSTTTPGL 2045

Query: 420  GEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADVTGSS--ASYP 477
             E      S   + SP S   T+S +         T+  +   STTS    GS+   ++P
Sbjct: 2046 SE-----KSTTFHSSPRSPATTLSPA-------STTSSGVSEESTTSHSRPGSTHTTAFP 2093

Query: 478  EGVNASVLTQFSDSTVQSGGSHTALGDRSYSESSSTSSSESLNSSAPRGERSIAGISYGQ 537
            +      L++ S ++  S GS T       S ++S  S ES  S +  G    A +S G 
Sbjct: 2094 DSTTTPGLSRHSTTSHSSPGS-TDTTLLPASTTTSGPSQESTTSHSSPGSTDTA-LSPGS 2151

Query: 538  VRGTAIEQRTSSDHTDHTYLSSTFTKGERALLSITDNSSSSDIVESSTSYIKISNSSHS- 596
                +  Q +++ H+         + G        D+++SS IVE+ST     + S  + 
Sbjct: 2152 TTALSFGQESTTFHS---------SPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTT 2202

Query: 597  -------------EYSSFFHAQTERSNISSYDGEYAQPSTESPVLHTSNLPSYTPTINMP 643
                         E ++F           S       P  ES   H S  P  TPT + P
Sbjct: 2203 LSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRS--PGSTPTTHFP 2260

Query: 644  NTSVVL-----DTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSILPSTRAS 698
             +S         T      D+S ++ SS+ S++SG      S         + LP +  +
Sbjct: 2261 ASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTT 2320

Query: 699  VHLLK-STSDASTPWSSSPSPLPVSLT---------TSTSAPLSVSQTTLPQSSSTPVLP 748
              L + ST+  S+P S + +  P S+T         TS S P S   T  P S++TP L 
Sbjct: 2321 PGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLS 2380

Query: 749  RARETPVTSFQTSTMTSFM-----TMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPT 803
                T  +S   ST T+       T +   +     S+       + TE  + S   L  
Sbjct: 2381 EESTTVYSSSPGSTETTVFPRTPTTSVRGEEPTTFHSRPASTHTTLFTEDSTTS--GLTE 2438

Query: 804  EST----KAVTTNSPLPPSLT-----ESSTEQTLPATSTNL-AQMSPTFTTT--ILKTSQ 851
            EST       +T + LP +LT     E ST  T P++S +    +SP  +TT  ++  S 
Sbjct: 2439 ESTAFPGSPASTQTGLPATLTTADLGEEST--TFPSSSGSTGTTLSPARSTTSGLVGEST 2496

Query: 852  PLMTTPGTLSST---ASLVTGPIAVQTTAGKQLSLTHPEILVPQISTEGGISTERNRVIV 908
            P   +P +  +T    S  T  ++ ++T       +    L P  +T  G+S E      
Sbjct: 2497 PSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEE------ 2550

Query: 909  DATTGLIPLTSVPTSAKEMTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSATF 968
             +T+   P ++  T+  + TT  G++   + +  S G          ST   L P S T 
Sbjct: 2551 SSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPG----------STDTTLLPASTT- 2599

Query: 969  AVQSSTQSPTTVSSSASVNSCAVNP 993
                 +Q  TT  SS      A++P
Sbjct: 2600 -TSGPSQESTTSHSSPGSTDTALSP 2623



 Score =  108 bits (271), Expect = 3e-23
 Identities = 241/1020 (23%), Positives = 384/1020 (37%), Gaps = 115/1020 (11%)

Query: 64   PPPTPPRERRGPATPGP-SYRAPE----PGAATQRGPSGRAPRGGSADAA--WKHWPESN 116
            P  + P    G +TP P S  + E    PG+ T+ G S ++    S+  +    H P S 
Sbjct: 596  PAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASM 655

Query: 117  TEAHVENITFYQNQEDFSTVSSK---EGVMVQTSGKSHAASDAPENLTLLAETADARGRS 173
            T + V   +   +    ST ++       M   S +S A+  +P               S
Sbjct: 656  TSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASS 715

Query: 174  GSSSRTNFTILPVGYSLEIATALTSQSGNL-ASESLHLPSSSSEFDERIAAFQTKSGTA- 231
                 T F   P      +    T+ SG L AS  +H  + S       A   T+ G + 
Sbjct: 716  LGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGEST 775

Query: 232  ------SEMGTERAMGLSEEWTVHSQEATTSAWSPSFLPALEMGELTTPS------RKRN 279
                  S   T  A   +    V  + +TTS  SPS +P   +   +T S         +
Sbjct: 776  TFHSWPSSKDTRPAPPTTTSAFV--EPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYH 833

Query: 280  SSGPDLSWLHFYRTAASSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGG 339
            SS      +HF  +  +S         EST   +++T   SS+ S T  +          
Sbjct: 834  SSPGSTQTMHFPESDTTS-----GRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSS 888

Query: 340  PRTLRSLTVSLGPVSKTEGFPKDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEP 399
            P +  + T      S T G  ++S  A+ SS        + +R  + V      E    P
Sbjct: 889  PGS--TATTHFPDSSTTSGRSEEST-ASHSSQDATGTIVLPARSTTSVLLG---ESTTSP 942

Query: 400  STENEFGLTSLRWQNDSPTFGEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWL 459
             +      T+L     +P   E      S   + SP S   T+S +         T+  +
Sbjct: 943  ISSGSMETTALPGSTTTPGLSER-----STTFHSSPRSPATTLSPA-------STTSSGV 990

Query: 460  LTNSTTSADVTGSS--ASYPEGVNASVLTQFSDSTVQSGGS-HTALGDRSY-----SESS 511
               STTS    GS+   ++P+      L++ S ++  S GS  T L   S      S+ S
Sbjct: 991  SEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQES 1050

Query: 512  STSSSESLNSSAPRGERSIAGISYGQVRGTAIEQRTSSDHTDHTYLSSTFTKGERALLSI 571
            +TS S S ++       S   +S+GQ   T       S HT     S+T +    A   +
Sbjct: 1051 TTSHSSSGSTDTALSPGSTTALSFGQ-ESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRV 1109

Query: 572  TDNSSSSDIVESSTSYIKISNSSHSEYSSFFHAQTERSNISSYDGEYAQPSTESPVLHTS 631
              ++ S     S  S    S     E ++F           S       P  ES   H S
Sbjct: 1110 HSSTGSPRTTLSPAS--STSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRS 1167

Query: 632  NLPSYTPTINMPNTSVVL-----DTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHH 686
              P  TPT + P +S         T      D+S ++ SS+ S++SG      S      
Sbjct: 1168 --PGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGS 1225

Query: 687  LFSSILPSTRASVHLLK-STSDASTPWSSSPSPLPVSLT---------TSTSAPLSVSQT 736
               + LP +  +  L + ST+  S+P S + +  P S+T         TS S P S   T
Sbjct: 1226 TEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHST 1285

Query: 737  TLPQSSSTPVLPRARETPVTSFQTSTMT-----SFMTMLHSSQTADLKSQSTPHQEKVIT 791
              P S++TP L     T  +S + ST T     S  T +H  +     S+       + T
Sbjct: 1286 VSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFT 1345

Query: 792  ESKSPSLVSLPTEST----KAVTTNSPLPPSLT-----ESSTEQTLPATSTNL-AQMSPT 841
            E  + S   L  EST       +T + LP +LT     E ST  T P++S +   ++SP 
Sbjct: 1346 EDSTTS--GLTEESTAFPGSPASTQTGLPATLTTADLGEEST--TFPSSSGSTGTKLSPA 1401

Query: 842  FTTT--ILKTSQPLMTTPGTLSST---ASLVTGPIAVQTTAGKQLSLTHPEILVPQISTE 896
             +TT  ++  S P   +P +  +T    S  T  ++ ++T       +    L P  +T 
Sbjct: 1402 RSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTS 1461

Query: 897  GGISTERNRVIVDATTGLIPLTSVPTSAKEMTTKLGVTAEYSPASRSLGTSPSPQTTVVS 956
             G+S E       +T+   P ++  T+  + TT   ++ E + +  S G++ +  +   +
Sbjct: 1462 SGVSEE------SSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGST 1515

Query: 957  TAEDLAPKSATFAVQSSTQSPT-----TVSS---SASVNSCAVNPCLHNGECVADNTSRG 1008
            TA  L  +S TF         T     T++S    AS  + +    LH     A +TS G
Sbjct: 1516 TASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAG 1575



 Score =  103 bits (256), Expect = 1e-21
 Identities = 249/1023 (24%), Positives = 393/1023 (38%), Gaps = 124/1023 (12%)

Query: 34   PPSPARRALSLAPLAGAGLELQLERRPER-EPPPTPPRERRG-PATPGPS------YRAP 85
            P S       L+P       L  E  P R  P  T      G P TP  S      Y +P
Sbjct: 1388 PSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSP 1447

Query: 86   EPGAATQRGPSGRAPRGGSADAAWKHWP--ESNTEAHVENITFYQNQEDFSTVSSKEGVM 143
                AT   P+     G S +++  H     ++T A  ++ T     ++ +T  S +G  
Sbjct: 1448 RSPDATL-SPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGST 1506

Query: 144  VQT--SGKSHAASDAPENLTLLAETADARGRSGSSSRTNFTILP----VGYSLEIATALT 197
              T   G + A+S   ++ T  +   D          T  T+LP        +E +T   
Sbjct: 1507 EATLSPGSTTASSLGQQSTTFHSSPGD----------TETTLLPDDTITSGLVEASTPTH 1556

Query: 198  SQSGNLASESLHLPSSSSEFDERIAAFQT----KSGTASEMGTERAMGLSEEWTVHSQEA 253
            S +G+L +      S+S+   E    FQ+       T S  GT  A  +    T HS+ +
Sbjct: 1557 SSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAP-VEVSTTYHSRPS 1615

Query: 254  TTSA--WSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASSPLLDLSSSSESTEK 311
            +T    +S S        E TT      ++G  L    F   +A+S L+   ++S  +  
Sbjct: 1616 STPTTHFSASSTTLGRSEESTTVHSSPGATGTAL----FPTRSATSVLVGEPTTSPISSG 1671

Query: 312  LNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVSKT------EGFPKDSRI 365
               +T L  S+ +   +    T ++       RS   +L P S T      E     SR 
Sbjct: 1672 STETTALPGSTTTAGLSEKSTTFYSSP-----RSPDTTLSPASTTSSGVSEESTTSHSRP 1726

Query: 366  ATTSSSVLLSPSAVE--SRRNSRVTGNPGDEEF-IEP--STENEFGLTSLRWQNDSPTFG 420
             +T ++     + +   S+ ++    +PG  +  + P  +T +  G  S  + + SP   
Sbjct: 1727 GSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHS-SPGST 1785

Query: 421  EHQLASSSEVQNG----------SPMSQTETVSRSVAPMRGGEITAH--WLLTNSTTSAD 468
            E  L   +   +G          S  S   T+S + +  R GE T    W  +  T  A 
Sbjct: 1786 ETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAP 1845

Query: 469  VTGSSASYPEGVNASVLTQFSDSTVQSGGSHTALGDRSYSESSSTSSSESLNSSAPRGER 528
             T +SA + E    S  +  S  T     S T LG RS  ES++  SS    ++ P   R
Sbjct: 1846 PTTTSA-FVELSTTSHGSPSSTPTTHFSASSTTLG-RS-EESTTVHSSPVATATTPSPAR 1902

Query: 529  SIAGISYGQVR-GTAIEQRTSSDHTDHTYLSSTFT-KGERALLSITDN--------SSSS 578
            S      G V   TA      S  T H   SST + + E +  S +          S++S
Sbjct: 1903 STTS---GLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTS 1959

Query: 579  DIVESSTSYIKISNSS---HSEYSSFFHAQTERSNISSYDGEYAQPSTESPVLHTSNLPS 635
             +VE  TSY     S+   H   SS    ++E S  +S+  + A  +   P   T+++  
Sbjct: 1960 ALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEEST-ASHSSQDATGTIVLPARSTTSVLL 2018

Query: 636  YTPTINMPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSILPST 695
               T + P +S  ++T A   S ++   S  S++  S P  P  ++S +    S +   +
Sbjct: 2019 GESTTS-PISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEES 2077

Query: 696  RASVHLLKSTSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQSSSTPVLPRARETPV 755
              S     ST   + P S++   L    TTS S+P S   T LP S++            
Sbjct: 2078 TTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTT------------ 2125

Query: 756  TSFQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPL 815
                TS  +   T  HSS  +   + S      +    +S +  S P  +   +  +S  
Sbjct: 2126 ----TSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTT 2181

Query: 816  PPSLTESSTEQTLPATSTNLAQMSPTFTTT--ILKTSQPLMTTPG---TLSSTASLVTGP 870
               + E+ST +   +T +    +SP  +T+  +   S    T P    T  S  S  T P
Sbjct: 2182 SSGIVEAST-RVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAP 2240

Query: 871  IAVQTTAGKQLSLTHPEILVPQISTEGGISTERNRVIVDATTGLIPLTSVPTSAKEMTTK 930
            +   TT  +    T P    P  ST  G S E++ +   +        + P+SA   T+ 
Sbjct: 2241 VEESTTYHRSPGST-PTTHFPASSTTSGHS-EKSTIFHSSPDA---SGTTPSSAHSTTSG 2295

Query: 931  LG--VTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSATFAVQSSTQSPTTVSSSASVNS 988
             G   T+  SP S  + T P   TT       L+  S TF   SS +SPTT  S AS+ S
Sbjct: 2296 RGESTTSRISPGSTEITTLPGSTTT-----PGLSEASTTF--YSSPRSPTTTLSPASMTS 2348

Query: 989  CAV 991
              V
Sbjct: 2349 LGV 2351



 Score =  103 bits (256), Expect = 1e-21
 Identities = 246/1019 (24%), Positives = 391/1019 (38%), Gaps = 116/1019 (11%)

Query: 34   PPSPARRALSLAPLAGAGLELQLERRPER-EPPPTPPRERRG-PATPGPS------YRAP 85
            P S      +L+P       L  E  P R  P  T      G P TP  S      Y +P
Sbjct: 2945 PSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSP 3004

Query: 86   EPGAATQRGPSGRAPRGGSADAAWKHWPESNTEAHVENITFYQNQEDFSTVSSKEGVMVQ 145
                AT   P+     G S +++  H    +T       T + +    S +S +      
Sbjct: 3005 RSPDATL-SPATTTSSGVSEESSTSHSQPGSTHT-----TAFPDSTTTSGLSQEPTASHS 3058

Query: 146  TSGKSHAASDAPENLTLLAETADARGRSGSSSRTNFTILP----VGYSLEIATALTSQSG 201
            + G + A   +P + T  +    +     S   T  T+LP        +E +T   S +G
Sbjct: 3059 SQGSTEATL-SPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTG 3117

Query: 202  NLASESLHLPSSSSEFDERIAAFQT----KSGTASEMGTERAMGLSEEWTVHSQEATTSA 257
            +L +      S+S+   E    FQ+       T S  GT  A  +    T HS+ ++T  
Sbjct: 3118 SLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAP-VEVSTTYHSRPSSTPT 3176

Query: 258  --WSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASSPLLDLSSSSESTEKLNNS 315
              +S S        E TT      ++G  L    F   +A+S L+   ++S  +     +
Sbjct: 3177 THFSASSTTLGRSEESTTVHSSPGATGTAL----FPTRSATSVLVGEPTTSPISSGSTET 3232

Query: 316  TGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVSKT------EGFPKDSRIATTS 369
            T L  S+ +   +    T ++       RS   +L P S T      E     SR  +T 
Sbjct: 3233 TALPGSTTTAGLSEKSTTFYSSP-----RSPDTTLSPASTTSSGVSEESTTSHSRPGSTH 3287

Query: 370  SSVLLSPSAVE--SRRNSRVTGNPGDEEF-IEP--STENEFGLTSLRWQND--------- 415
            ++     + +   S+ ++    +PG  +  + P  +T +  G  S  + +          
Sbjct: 3288 TTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSGPGSTETTLL 3347

Query: 416  -SPTFGEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAH--WLLTNSTTSADVTGS 472
               T     L +S+ V + +    T T+S + +  R GE T    W  +  TT A  T +
Sbjct: 3348 PDNTTASGLLEASTPVHSSTGSPHT-TLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTT 3406

Query: 473  SASYPEGVNASVLTQFSDSTVQSGGSHTALGDRSYSESSSTSSSESLNSSAPRGERSIAG 532
            SA + E    S  +  S  T     S T LG RS  ES++  SS    ++ P   RS   
Sbjct: 3407 SA-FVELSTTSHGSPSSTPTTHFSASSTTLG-RS-EESTTVHSSPVATATTPSPARSTTS 3463

Query: 533  ISYGQVR-GTAIEQRTSSDHTDHTYLSSTFT-KGERALLSITDN--------SSSSDIVE 582
               G V   T       S  T H   S T + +GE +  S +          S++S +VE
Sbjct: 3464 ---GLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVE 3520

Query: 583  SSTSYIKISNSS---HSEYSSFFHAQTERSNISSYDGEYAQPSTESPVLHTSNLPSYTPT 639
              TSY     S+   H   SS    ++E S  +S+  + A  +   P   T+++     T
Sbjct: 3521 EPTSYHSSPGSTATTHFPDSSTTSGRSEEST-ASHSSQDATGTIVLPARSTTSVLLGEST 3579

Query: 640  INMPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSILPSTRASV 699
             + P +S  ++T A   S ++   S  S++  S P  P  ++S +    S +   +  S 
Sbjct: 3580 TS-PISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSH 3638

Query: 700  HLLKSTSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQSSSTPVLPRARETPVTSFQ 759
                ST   + P S++   L    TTS S+P S   T LP S++T            S Q
Sbjct: 3639 SRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTS----------GSSQ 3688

Query: 760  TSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSL 819
             ST +      HSS  +   + S      +    +S +  S P  +   +  +S     +
Sbjct: 3689 ESTTS------HSSSGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGI 3742

Query: 820  TESSTEQTLPATSTNLAQMSPTFTTT--ILKTSQPLMTTPG---TLSSTASLVTGPIAVQ 874
             E+ST +   +T +    +SP  +T+  +   S    T P    T  S  S  T P+   
Sbjct: 3743 VEAST-RVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEES 3801

Query: 875  TTAGKQLSLTHPEILVPQISTEGGISTERNRVIVDATTGLIPLTSVPTSAKEMTTKLG-- 932
            TT  +    T P    P  ST  G S E++ +   +        + P+SA   T+  G  
Sbjct: 3802 TTYHRSPGST-PTTHFPASSTTSGHS-EKSTIFHSSPDA---SGTTPSSAHSTTSGRGES 3856

Query: 933  VTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSATFAVQSSTQSPTTVSSSASVNSCAV 991
             T+  SP S  + T P   TT       L+  S TF   SS +SPTT  S AS+ S  V
Sbjct: 3857 TTSRISPGSTEITTLPGSTTT-----PGLSEASTTF--YSSPRSPTTTLSPASMTSLGV 3908



 Score =  103 bits (256), Expect = 1e-21
 Identities = 222/921 (24%), Positives = 349/921 (37%), Gaps = 115/921 (12%)

Query: 134  STVSSKEGVMVQTSGKSHAASDAPENLTLLAETADARGRSGSSSRTNFTILPVGYSLEIA 193
            S   S    +V  S  S  +  + E  TL          S S   T F   P      ++
Sbjct: 4039 SPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTP---SLSEKSTTFYTSPRSPDATLS 4095

Query: 194  TALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTASEMGTERAMGLSEEWTVH---- 249
             A T+ SG     S       S          T SG + E  T  +   S E T+     
Sbjct: 4096 PATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLSPGST 4155

Query: 250  -----SQEATTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSW---LHFYRTAASSPLLD 301
                  Q++TT   SP       + + T  S    +S P  S    LH   T ASS    
Sbjct: 4156 TASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSTG 4215

Query: 302  LSSSSESTEKLNNSTGLQSSSVSQTKT-MHVATVFTDGGPRTLRSLTVSLGPVSKTEGFP 360
            L   S + +   +S+    S  S T   + V+T +     R   + T      S T G  
Sbjct: 4216 LQEESTTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHS---RPSSTPTTHFSASSTTLGRS 4272

Query: 361  KDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQNDSPTFG 420
            ++S    +S     +         S + G P        STE     T+L     + T G
Sbjct: 4273 EESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTET----TAL--PGSTTTAG 4326

Query: 421  EHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADVTGS--SASYPE 478
               L+  S     SP S   T+S +         T+  +   STTS    GS  + ++P 
Sbjct: 4327 ---LSEKSTTFYSSPRSPDTTLSPA-------STTSSGVSEESTTSHSRPGSMHTTAFPS 4376

Query: 479  GVNASVLTQFSDSTVQSGGS-HTALGDRSYSESSSTSSSESLNSSAPRGERSIAG---IS 534
                  ++Q S ++  S GS  T L   S + SS    S + +SS    E ++      +
Sbjct: 4377 STTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTA 4436

Query: 535  YGQVRG-TAIEQRTSSDHTDHTYLSSTFTKGERALLSITDNSSSSDIVESSTS--YIKIS 591
             G +   T +   T S HT  +   ST  +GE        NS  +     +T+  ++++S
Sbjct: 4437 SGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELS 4496

Query: 592  NSSHSEYSS----FFHAQTE---RSNISS--YDGEYAQPSTESPVLHTSN---------- 632
             +SH   SS     F A +    RS  S+  +    A  +T SP   T++          
Sbjct: 4497 TTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYH 4556

Query: 633  -LPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSI 691
              P  T T++ P ++       E    S++S SS++ + SS P      V +     SS 
Sbjct: 4557 SSPGSTQTMHFPESNTTSGRGEE----STTSHSSTTHTISSAPSTTSALVEEPTSYHSS- 4611

Query: 692  LPSTRASVHLLKST-----SDASTPWSSSPSP-----LPVSLTTS------TSAPL---S 732
             P + A+ H   S+     S+ ST   SS        LP   TTS      T++P+   S
Sbjct: 4612 -PGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGS 4670

Query: 733  VSQTTLPQSSSTPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITE 792
            +  T LP S++TP L   + T   S  +ST T+  +   SS T     +ST      +  
Sbjct: 4671 METTALPGSTTTPGLSE-KSTTFHSSPSSTPTTHFSA--SSTTLGRSEESTTVHSSPVAT 4727

Query: 793  SKSPSLVSLPTESTKAVTTNSPLPPSLTESSTEQTLPATSTNLAQMSPTFTTTILKTSQP 852
            + +PS    P  ST +           +  ST+      S+  +  S    T+   T+  
Sbjct: 4728 ATTPS----PARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHT 4783

Query: 853  LMTTPGTLSSTASLVTGPIAVQTTAGKQLSLTHPEILVPQISTEGGISTERNRVIVDA-T 911
            + + P   S+T++LV  P +  ++ G  ++ TH     P+ ST  G S E         T
Sbjct: 4784 ISSPP---STTSALVEEPTSYHSSPG-SIATTH----FPESSTTSGRSEESTASHSSPDT 4835

Query: 912  TGLIPLTSVPTSAKEMTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSATFAVQ 971
             G+ PL +  T++  +      T   SP S         +TT+ STA      + +  + 
Sbjct: 4836 NGITPLPAHFTTSGRIAE--STTFYISPGSM--------ETTLASTATTPGLSAKSTILY 4885

Query: 972  SSTQSPTTVSSSASVNSCAVN 992
            SS++SP    S AS+ S +++
Sbjct: 4886 SSSRSPDQTLSPASMTSSSIS 4906



 Score = 92.4 bits (228), Expect = 3e-18
 Identities = 218/922 (23%), Positives = 339/922 (36%), Gaps = 130/922 (14%)

Query: 113  PESNTEAHVENITFYQNQEDFSTVSSKEGVMVQTSGKSHAASDAPENLTLLAETADARGR 172
            P   T A V+  T Y +    ST ++       T G S  ++    +    A T     R
Sbjct: 434  PSGTTSAFVKLSTTYHSSPS-STPTTHFSASSTTLGHSEESTPVHSSPVATATTPPP-AR 491

Query: 173  SGSSSRTNFTILPVGYSLEIATALTSQSGNLASESLHLPSSS--SEFDERIAAFQ----- 225
            S +S             +E +TA     G+  ++++H P SS  S   E  A F      
Sbjct: 492  SATSGH-----------VEESTAYHRSPGS--TQTMHFPESSTTSGHSEESATFHGSTTH 538

Query: 226  ----TKSGTASEMGTERAMGLSEEWTVH----------SQEATTSAWSPSFLPALEMGEL 271
                T S TA+   T     L    T H          S+E+  S  SP  +    +   
Sbjct: 539  TKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAG 598

Query: 272  TTPSRKRNSSGPDLSWLHFYRTAASSPLLDLSSSSESTEK--LNNSTGLQSSSVSQTKTM 329
            +TPS     S P         +  SS  ++ ++   ST K  L+  +    SS     T 
Sbjct: 599  STPSVLVGDSTP---------SPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTT 649

Query: 330  HVATVFTDGGPRTLRSLTVSLGPVSKTEGFPKDSRIATTSSSVLLSPSAVESRRNSRVTG 389
            H+    T  G     + + S    + T  FP  + +   S     S S   S   +  T 
Sbjct: 650  HLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHS---SPGPTDTTL 706

Query: 390  NPGDEEFIEPSTE-----NEFGLTSLRWQNDSPTFGEHQLASSSEVQNGSPMSQTETVSR 444
            +PG         E     +  G T      D+ T     L  +S   + S  S   T+S 
Sbjct: 707  SPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASG--LLEASMPVHSSTRSPHTTLSP 764

Query: 445  SVAPMRGGEITAH--WLLTNSTTSADVTGSSASYPEGVNASVLTQFSDSTVQSGGSHTAL 502
            + +  R GE T    W  +  T  A  T +SA             F + +  S GS +++
Sbjct: 765  AGSTTRQGESTTFHSWPSSKDTRPAPPTTTSA-------------FVEPSTTSHGSPSSI 811

Query: 503  GDRSYSESSSTSS---SESLNSSAPRGERSIAGISYGQVRGTAIEQRTSSDHTDHTYLSS 559
                 S  S+TS      +   S+P   +++         G   E  TS   T HT  S+
Sbjct: 812  PTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSA 871

Query: 560  TFTKGERALLSITDNSSSSDIVESSTSYIKISNSS---HSEYSSFFHAQTERSNISSYDG 616
                           S++S +VE  TSY     S+   H   SS    ++E S  +S+  
Sbjct: 872  P--------------STTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEEST-ASHSS 916

Query: 617  EYAQPSTESPVLHTSNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPL 676
            + A  +   P   T+++     T + P +S  ++T A   S ++   S  S++  S P  
Sbjct: 917  QDATGTIVLPARSTTSVLLGESTTS-PISSGSMETTALPGSTTTPGLSERSTTFHSSPRS 975

Query: 677  PLPSVSQSHHLFSSILPSTRASVHLLKSTSDASTPWSSSPSPLPVSLTTSTSAPLSVSQT 736
            P  ++S +    S +   +  S     ST   + P S++   L    TTS S+P S   T
Sbjct: 976  PATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTT 1035

Query: 737  TLPQSSSTPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSP 796
             LP S++                TS  +   T  HSS  +   + S      +    +S 
Sbjct: 1036 LLPASTT----------------TSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQEST 1079

Query: 797  SLVSLPTESTKAVTTNSPLPPSLTESSTEQTLPATSTNLAQMSPTFTTT--ILKTSQPLM 854
            +  S P  +   +  +S     + E+ST +   +T +    +SP  +T+  +   S    
Sbjct: 1080 TFHSNPGSTHTTLFPDSTTSSGIVEAST-RVHSSTGSPRTTLSPASSTSPGLQGESTAFQ 1138

Query: 855  TTPG---TLSSTASLVTGPIAVQTTAGKQLSLTHPEILVPQISTEGGISTERNRVIVDAT 911
            T P    T  S  S  T P+   TT  +    T P    P  ST  G S E++ +   + 
Sbjct: 1139 THPASTHTTPSPPSTATAPVEESTTYHRSPGST-PTTHFPASSTTSGHS-EKSTIFHSSP 1196

Query: 912  TGLIPLTSVPTSAKEMTTKLG--VTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSATFA 969
                   + P+SA   T+  G   T+  SP S  + T P   TT       L+  S TF 
Sbjct: 1197 DA---SGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTT-----PGLSEASTTF- 1247

Query: 970  VQSSTQSPTTVSSSASVNSCAV 991
              SS +SPTT  S AS+ S  V
Sbjct: 1248 -YSSPRSPTTTLSPASMTSLGV 1268



 Score = 76.6 bits (187), Expect = 1e-13
 Identities = 172/764 (22%), Positives = 272/764 (35%), Gaps = 146/764 (19%)

Query: 298 PLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVSKTE 357
           PL + + ++ + EK    T +  S+ S    +  +TV T  G  T  + T          
Sbjct: 133 PLSEQARAAGAREKERQETVINHSTFSGFSQITGSTVNTSIGGNTTSAST---------- 182

Query: 358 GFPKDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQNDSP 417
             P  S   TT S   +S + +        TG+   + F++ ST +     S    +   
Sbjct: 183 --PSSSDPFTTFSDYGVSVTFI--------TGSTATKHFLDSSTNSGHSEESTVSHSGPG 232

Query: 418 TFGEHQLASSS--EVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTT------SADV 469
             G     S S   V  G P +   T +        G  T   L   STT      S D 
Sbjct: 233 ATGTTLFPSHSATSVFVGEPKTSPITSASMETTALPGSTTTAGLSEKSTTFYSSPRSPDR 292

Query: 470 TGSSA-SYPEGVNASVLTQ-----------FSDSTVQSGGSHTALGDRSYSESSSTSSSE 517
           T S A +   GV+    T            F DST   G S  +    S   S+ T+ S 
Sbjct: 293 TLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDSTTMPGVSQESTASHSIPGSTDTTLSP 352

Query: 518 SLNSSAPRG-ERSIAGISYGQVR----------------GTAIEQRTSSDHTDHTYLSST 560
              + +  G E +    S G  +                 T +   T S HT  +  SST
Sbjct: 353 GTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEASTPVHSSTGSPHTTLSPSSST 412

Query: 561 FTKGERALLSITDNSSSSDIVESST--SYIKISNSSHSEYSSFFHAQTERSNISSYDGEY 618
             +GE        +S  +    S T  +++K+S + HS  SS        S+ +    E 
Sbjct: 413 THEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEE 472

Query: 619 AQPSTESPVLHTS--------------------NLPSYTPTINMPNTSVVLDTDAEFVSD 658
           + P   SPV   +                      P  T T++ P +S       E  + 
Sbjct: 473 STPVHSSPVATATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESATF 532

Query: 659 SSSSSSSSSSSSSSGPPL-------PLPSVSQSHHLFSSILPSTRASVHLLKSTSDAST- 710
             S++ + SS+ S+   L        L S   +H   SS +           S+ DA   
Sbjct: 533 HGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESKASHSSPDAMAT 592

Query: 711 ---PWSSSPSPLPVSLTTSTSAPLSVSQTTLPQSSSTPVLPRARETPVTSFQTSTMTSFM 767
              P  S+PS L    T S  +  S+  T LP S++ P L        T+F +S  +   
Sbjct: 593 TVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPGLSEKS----TTFYSSPRSPDT 648

Query: 768 TMLHSSQTADLKSQ--STPHQEKVITESKS-PSLVSLPTESTKAVTTNSPLPPSLTESST 824
           T L +S T+   S+  +T H     T + + P   ++P  S ++  ++S   P      T
Sbjct: 649 THLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGP------T 702

Query: 825 EQTLPATSTNLAQMSPTFTTTILKTSQPLMTTPGTLSSTASLVTGPIAVQTTAGKQLSLT 884
           + TL   ST  + + P +TT          + PG+  +T                     
Sbjct: 703 DTTLSPGSTTASSLGPEYTT--------FHSRPGSTETT--------------------- 733

Query: 885 HPEILVPQISTEGGISTERNRVIVDATTGLIPLTSVPTSAKEMTTKLGVTAEYSPASRSL 944
               L+P  +T  G+  E +  +  +T    P T++  S    TT+ G +  +     S 
Sbjct: 734 ----LLPDNTTASGL-LEASMPVHSSTRS--PHTTL--SPAGSTTRQGESTTFHSWPSSK 784

Query: 945 GTSPSPQTTVVSTAEDLAPKSATFAVQSSTQSPTTVSSSASVNS 988
            T P+P TT  +  E      +T +  S +  PTT  S+ S  S
Sbjct: 785 DTRPAPPTTTSAFVE-----PSTTSHGSPSSIPTTHISARSTTS 823



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 98/437 (22%), Positives = 164/437 (37%), Gaps = 58/437 (13%)

Query: 594 SHSEYSSFFHAQTERSNISSYDGEYAQPSTESPVLHTSNLPSYTPTINMPNTSVVLDTDA 653
           +HS +S F        N +S  G     ST S     +    Y  ++    T +   T  
Sbjct: 154 NHSTFSGFSQITGSTVN-TSIGGNTTSASTPSSSDPFTTFSDYGVSV----TFITGSTAT 208

Query: 654 EFVSDSSSSSSSSSSS--SSSGPPLPLPSVSQSHHLFSSILPSTRASVHLLKSTSDASTP 711
           +   DSS++S  S  S  S SGP     ++  SH   S  +   + S     S    + P
Sbjct: 209 KHFLDSSTNSGHSEESTVSHSGPGATGTTLFPSHSATSVFVGEPKTSPITSASMETTALP 268

Query: 712 WSSSPSPLPVSLTTSTSAPLSVSQTTLPQSSSTPVLPRARETPVTSFQTSTMTSFMTMLH 771
            S++ + L    TT  S+P S  +T  P  +++       E   TS      T  +    
Sbjct: 269 GSTTTAGLSEKSTTFYSSPRSPDRTLSPARTTS---SGVSEKSTTSHSRPGPTHTIAFPD 325

Query: 772 SSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSL-TESSTEQTLPA 830
           S+    +  +ST                S+P  +   ++  +  P SL  ES+T  + P 
Sbjct: 326 STTMPGVSQESTASH-------------SIPGSTDTTLSPGTTTPSSLGPESTTFHSSPG 372

Query: 831 TSTNLAQMSPTFTTTILKTSQPLMTTPG----TLSSTASLV----------------TGP 870
            +        T T+ +L+ S P+ ++ G    TLS ++S                  T P
Sbjct: 373 YTKTTRLPDNTTTSGLLEASTPVHSSTGSPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSP 432

Query: 871 IAVQTT-AGKQLSLTH-------PEILVPQISTEGGISTERNRVIVDATTGLIPLTSVPT 922
               TT A  +LS T+       P       ST  G S E   V     +  +   + P 
Sbjct: 433 APSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPV----HSSPVATATTPP 488

Query: 923 SAKEMTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSATFAVQSSTQSPTTVSS 982
            A+  T+  G   E +   RS G++ +      ST    + +SATF   ++    +T S+
Sbjct: 489 PARSATS--GHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPST 546

Query: 983 SASVNSCAVNPCLHNGE 999
           +A++   + +  L + E
Sbjct: 547 TAALAHTSYHSSLGSTE 563


>gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo
            sapiens]
          Length = 2036

 Score =  116 bits (291), Expect = 1e-25
 Identities = 248/1004 (24%), Positives = 378/1004 (37%), Gaps = 147/1004 (14%)

Query: 68   PPRERRGPATPGPSYRAPEPGAATQRGPSGRAPRGGSADAAWKHWPESNTEAHVENITFY 127
            P  +   PA P  +    EP   +   PS       SA +      E +T  H    +  
Sbjct: 268  PSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQ 327

Query: 128  QNQEDFSTVSSKEGVMVQTSGKS--HAASDAPENLTLLAETADARGRS-GSSSRTNF--T 182
                  S  +S  G    TS  S  H  S AP   + L E   +   S GS++ T+F  +
Sbjct: 328  TMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDS 387

Query: 183  ILPVGYSLEIATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTASEMGTERAMGL 242
                G S E   + +SQ    A+ ++ LP+ S           T S    E  T      
Sbjct: 388  STTSGRSEESTASHSSQD---ATGTIVLPARS-----------TTSVLLGESTTSPISSG 433

Query: 243  SEEWTVHSQEATTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASSPLLDL 302
            S E T      TT        P L     T  S  R S    LS      +  SS + + 
Sbjct: 434  SMETTALPGSTTT--------PGLSERSTTFHSSPR-SPATTLS----PASTTSSGVSEE 480

Query: 303  SSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVSKTEGFPKD 362
            S++S S     ++T    S+ +   + H  T  +  G     S   +L P S T   P  
Sbjct: 481  STTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPG-----STDTTLLPASTTTSGPSQ 535

Query: 363  SRIATTSSS----VLLSPSAVES----RRNSRVTGNPGDEEF-IEPSTENEFGLTSLRWQ 413
                + SSS      LSP +  +    + ++    NPG     + P +    G+     +
Sbjct: 536  ESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTR 595

Query: 414  NDSPTFGEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITA---HWLLTNSTTSADVT 470
              S T              GSP +     S S +P   GE TA   H   T++T S   T
Sbjct: 596  VHSST--------------GSPRTTLSPAS-STSPGLQGESTAFQTHPASTHTTPSPPST 640

Query: 471  GS-----SASYPEGVNASVLTQFSDSTVQSGGSHTALGDRSYSESSSTSSSESLNSSAPR 525
             +     S +Y     ++  T F  S+  SG S  +    S  ++S T+ S + ++++ R
Sbjct: 641  ATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGR 700

Query: 526  GERSIAGISYGQVRGTAIEQRTSSDHTDHTYLSSTFTKGERALLSITDNSS--SSDIVES 583
            GE + + IS G    T +   T++        S+TF    R+  +    +S  S  + E 
Sbjct: 701  GESTTSRISPGSTEITTLPGSTTTPGLSEA--STTFYSSPRSPTTTLSPASMTSLGVGEE 758

Query: 584  STSYIKISNSSHSEYSSFFHAQTERSNISSYDGEYAQPSTESPVLHTSNLPS-------- 635
            ST+      S+HS  S         S  S+     ++ STE+ V   S   S        
Sbjct: 759  STTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTT 818

Query: 636  -YTPTINMPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSILPS 694
             ++   +   T    D+    +++ S++   S +S+ +G P  L +        S+  PS
Sbjct: 819  FHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEE--STTFPS 876

Query: 695  TRASVHLLKSTSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQSSSTPVLPRARETP 754
            +  S      T    +P  S+ S L    T S  +P S   TTLP S +TP L       
Sbjct: 877  SSGS------TGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKS--- 927

Query: 755  VTSFQTSTMTSFMTMLHSSQTADLKSQ--STPHQEKVITESKSPSLVSLPTESTKAVTTN 812
             T+F TS  +   T+  ++ T+   S+  ST H +   T +      + P  +T +  + 
Sbjct: 928  -TTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHT-----TAFPDSTTTSDLSQ 981

Query: 813  SPLPPSLTESSTEQTL---PATSTNLAQMSPTF-------TTTILK----TSQPLMTTPG 858
             P     ++ STE TL     T+++L Q S TF        TT+L     TS  +  +  
Sbjct: 982  EPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTP 1041

Query: 859  TLSSTASL-VTGPIAVQTTAG-KQLSLTHPEILVPQISTEGGISTERNRVIVDATTGLIP 916
            T SST SL  T   A  T+AG ++ S T         +T     T    V V  T    P
Sbjct: 1042 THSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRP 1101

Query: 917  LTSVPTSAKEMTTKLGVTAEYSPASRSLG---------------------TSP----SPQ 951
             ++  T     +T LG + E +    S G                     TSP    S +
Sbjct: 1102 SSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTE 1161

Query: 952  TTVV---STAEDLAPKSATFAVQSSTQSPTTVSSSASVNSCAVN 992
            TT +   +T   L+ KS TF   SS +SP T  S AS  S  V+
Sbjct: 1162 TTALPGSTTTAGLSEKSTTF--YSSPRSPDTTLSPASTTSSGVS 1203



 Score = 99.8 bits (247), Expect = 2e-20
 Identities = 259/1131 (22%), Positives = 395/1131 (34%), Gaps = 200/1131 (17%)

Query: 36   SPARRALSLAPLAGAGLELQLERRPEREPP------------PTPPRERRGP---ATPGP 80
            SP   A +L+P +     +  E    R  P             TP   R      ++PG 
Sbjct: 459  SPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGS 518

Query: 81   SYRAPEPGAATQRGPSGRAPRG----GSADAAWKHWPESNTEAHVENITFYQNQEDFSTV 136
            +     P + T  GPS  +       GS D A      +      E+ TF+ N     T 
Sbjct: 519  TDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTT 578

Query: 137  ----SSKEGVMVQTSGKSHAASDAPENLTLLAETADARGRSGSSSR-------TNFTILP 185
                S+    +V+ S + H+++ +P   TL   ++ + G  G S+        T+ T  P
Sbjct: 579  LFPDSTTSSGIVEASTRVHSSTGSPRT-TLSPASSTSPGLQGESTAFQTHPASTHTTPSP 637

Query: 186  VGYS---LEIATALTSQSGNLASESLHLPSSSSEFDERIAAFQTK---SGTASEM----- 234
               +   +E +T      G+  +      S++S   E+   F +    SGT         
Sbjct: 638  PSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTT 697

Query: 235  ----------------------GTERAMGLSEEWTVH--SQEATTSAWSPSFLPALEMGE 270
                                  G+    GLSE  T    S  + T+  SP+ + +L +GE
Sbjct: 698  SGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGE 757

Query: 271  LTTPSRKRNSSGPDLSWLHFYRTAASSPLLDLSSSSESTEKLNNSTGLQSSSV---SQTK 327
             +T SR +  S         + T + +       S EST   ++S G   ++V   S T 
Sbjct: 758  ESTTSRSQPGST--------HSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTT 809

Query: 328  TMHV--------------ATVFTDGGPR---TLRSLTVSLGPVSKTEGFPKDSRIATTSS 370
            ++H                T+FT+       T  S      P S   G P     A    
Sbjct: 810  SVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGE 869

Query: 371  SVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQN--DSPTFGEHQLASSS 428
                 PS+  S               +  ST +    +S        SPT     L+  S
Sbjct: 870  ESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPT--TPSLSEKS 927

Query: 429  EVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADVTGSS--ASYPEGVNASVLT 486
                 SP S   T+S +     G       +   S+TS    GS+   ++P+    S L+
Sbjct: 928  TTFYTSPRSPDATLSPATTTSSG-------VSEESSTSHSQPGSTHTTAFPDSTTTSDLS 980

Query: 487  QFSDSTVQSGGSHTA-LGDRSYSESSSTSSSESLNSSAPRGERSIAG---ISYGQVRG-T 541
            Q   ++  S GS  A L   S + SS    S + +SS    E ++     I+ G V   T
Sbjct: 981  QEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEAST 1040

Query: 542  AIEQRTSSDHTDHTYLSSTFTKGERALLSITDNSSSSDI-----------VESSTSYIKI 590
                 T S HT  T  SST    +    +     SSSD            VE ST+Y   
Sbjct: 1041 PTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSR 1100

Query: 591  SNSS-------------HSEYSSFFHAQT---------ERSNISSYDGEYAQPSTESPVL 628
             +S+              SE S+  H+            RS  S   GE       S   
Sbjct: 1101 PSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGST 1160

Query: 629  HTSNLPSYTPTINMPNTSVVL-------DTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSV 681
             T+ LP  T T  +   S          DT     S +SS  S  S++S S P     S 
Sbjct: 1161 ETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPG----ST 1216

Query: 682  SQSHHLFSSILPSTRASVHLLKSTSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQS 741
              +    S+ +P         +ST+  S+P S+  +  P S T S+  P S +  + P S
Sbjct: 1217 HTTAFPGSTTMPGVSQ-----ESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGS 1271

Query: 742  SSTPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSL 801
            + T +LP   +    S      T   +   S  T    + ST  Q +  T    PS  S 
Sbjct: 1272 TETTLLP---DNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPS--SK 1326

Query: 802  PTESTKAVTTNSPLPPSLTESSTEQTLP-----ATSTNLAQMSPTFTTTILKTSQPLMTT 856
             T      TT++ +  S T   +  + P     A+ST L +     +TT+  +     TT
Sbjct: 1327 DTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEE--STTVHSSPVATATT 1384

Query: 857  PGTLSSTAS-LVTGPIAVQTTAGKQLSLTHPEILVPQISTEGGISTERNRVIVDATTGLI 915
            P    ST S LV    A  ++ G   ++  PE      ST  G S E +R    +TT  I
Sbjct: 1385 PSPARSTTSGLVEESTAYHSSPGSTQTMHFPE-----SSTASGRS-EESRTSHSSTTHTI 1438

Query: 916  --------PLTSVPTSAKEMTTKLGVT--AEYSPAS----RSLGTSPSPQTTVVS----- 956
                     L   PTS       +  T   E S  S     S  +  SP T  ++     
Sbjct: 1439 SSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAH 1498

Query: 957  -TAEDLAPKSATFAVQSSTQSPTTVSSSASVNSCAVNPCLHNGECVADNTS 1006
             T      +S TF +   +   T  S++ +    A +  L+  + V + T+
Sbjct: 1499 FTTSGRIAESTTFYISPGSMETTLASTATTPGLSAKSTILYTSDLVGEPTT 1549



 Score = 88.2 bits (217), Expect = 5e-17
 Identities = 198/827 (23%), Positives = 305/827 (36%), Gaps = 115/827 (13%)

Query: 208 LHLPSSS--SEFDERIAAFQ---------TKSGTASEMGTERAMGLSEEWTVH------- 249
           +H P SS  S   E  A F          T S TA+   T     L    T H       
Sbjct: 1   MHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTI 60

Query: 250 ---SQEATTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASSPLLDLSSSS 306
              S+E+  S  SP  +    +   +TPS     S P         +  SS  ++ ++  
Sbjct: 61  SGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTP---------SPISSGSMETTALP 111

Query: 307 ESTEK--LNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVSKTEGFPKDSR 364
            ST K  L+  +    SS     T H+    T  G     + + S    + T  FP  + 
Sbjct: 112 GSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTT 171

Query: 365 IATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTE-----NEFGLTSLRWQNDSPTF 419
           +   S     S S   S   +  T +PG         E     +  G T      D+ T 
Sbjct: 172 MPGLSQESTASHS---SPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTA 228

Query: 420 GEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAH--WLLTNSTTSADVTGSSASYP 477
               L  +S   + S  S   T+S + +  R GE T    W  +  T  A  T +SA   
Sbjct: 229 SG--LLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSA--- 283

Query: 478 EGVNASVLTQFSDSTVQSGGSHTALGDRSYSESSSTSS---SESLNSSAPRGERSIAGIS 534
                     F + +  S GS +++     S  S+TS      +   S+P   +++    
Sbjct: 284 ----------FVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPE 333

Query: 535 YGQVRGTAIEQRTSSDHTDHTYLSSTFTKGERALLSITDNSSSSDIVESSTSYIKISNSS 594
                G   E  TS   T HT  S+               S++S +VE  TSY     S+
Sbjct: 334 SDTTSGRGEESTTSHSSTTHTISSAP--------------STTSALVEEPTSYHSSPGST 379

Query: 595 ---HSEYSSFFHAQTERSNISSYDGEYAQPSTESPVLHTSNLPSYTPTINMPNTSVVLDT 651
              H   SS    ++E S  +S+  + A  +   P   T+++     T + P +S  ++T
Sbjct: 380 ATTHFPDSSTTSGRSEEST-ASHSSQDATGTIVLPARSTTSVLLGESTTS-PISSGSMET 437

Query: 652 DAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSILPSTRASVHLLKSTSDASTP 711
            A   S ++   S  S++  S P  P  ++S +    S +   +  S     ST   + P
Sbjct: 438 TALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFP 497

Query: 712 WSSSPSPLPVSLTTSTSAPLSVSQTTLPQSSSTPVLPRARETPVTSFQTSTMTSFMTMLH 771
            S++   L    TTS S+P S   T LP S++                TS  +   T  H
Sbjct: 498 DSTTTPGLSRHSTTSHSSPGSTDTTLLPASTT----------------TSGPSQESTTSH 541

Query: 772 SSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESSTEQTLPAT 831
           SS  +   + S      +    +S +  S P  +   +  +S     + E+ST +   +T
Sbjct: 542 SSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEAST-RVHSST 600

Query: 832 STNLAQMSPTFTTT--ILKTSQPLMTTPG---TLSSTASLVTGPIAVQTTAGKQLSLTHP 886
            +    +SP  +T+  +   S    T P    T  S  S  T P+   TT  +    T P
Sbjct: 601 GSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGST-P 659

Query: 887 EILVPQISTEGGISTERNRVIVDATTGLIPLTSVPTSAKEMTTKLG--VTAEYSPASRSL 944
               P  ST  G S E++ +   +        + P+SA   T+  G   T+  SP S  +
Sbjct: 660 TTHFPASSTTSGHS-EKSTIFHSSPDA---SGTTPSSAHSTTSGRGESTTSRISPGSTEI 715

Query: 945 GTSPSPQTTVVSTAEDLAPKSATFAVQSSTQSPTTVSSSASVNSCAV 991
            T P   TT       L+  S TF   SS +SPTT  S AS+ S  V
Sbjct: 716 TTLPGSTTT-----PGLSEASTTF--YSSPRSPTTTLSPASMTSLGV 755



 Score = 83.2 bits (204), Expect = 2e-15
 Identities = 202/877 (23%), Positives = 332/877 (37%), Gaps = 136/877 (15%)

Query: 78   PGPSYRAPEPGAATQRGPSGRAP------RGGSADAAWKHWPESNTEAHVENITFYQNQE 131
            PG ++    P + T  G S  +       RG +    + H   + T  H E  T + ++ 
Sbjct: 766  PGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPH--STTTSVHGEEPTTFHSRP 823

Query: 132  D------FSTVSSKEGVMVQTSGKSHAASDAPENLTLLAETADARGRS----GSSSRTNF 181
                   F+  S+  G+  +++    + +     L     TAD    S     SS  T  
Sbjct: 824  ASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGT 883

Query: 182  TILPVGYSLE--IATALTSQSGNLASESLHLPSSSS--EFDERIAAFQTKSGTASEM--- 234
             + P   +    +  +  S+    ++E+  LP S +     E+   F T   +       
Sbjct: 884  KLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSP 943

Query: 235  GTERAMGLSEEW-TVHSQEATTSAWSPSFLPALEMGELTT-PSRKRNSSGPDLSWLHFYR 292
             T  + G+SEE  T HSQ  +T   + +F  +    +L+  P+   +S G   + L    
Sbjct: 944  ATTTSSGVSEESSTSHSQPGSTH--TTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGS 1001

Query: 293  TAASSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGP 352
            T ASS L   S++  S+     +T L   +++           +  G     SL  +L P
Sbjct: 1002 TTASS-LGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTG-----SLHTTLTP 1055

Query: 353  VSKT-----------EGFPKDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPST 401
             S T           + +P  S    +      +P  V +  +SR +  P        +T
Sbjct: 1056 ASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTP--------TT 1107

Query: 402  ENEFGLTSLRWQNDSPTFGEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLT 461
                  T+L    +S T        SS    G+ +  T    RS   +  GE T   + +
Sbjct: 1108 HFSASSTTLGRSEESTT------VHSSPGATGTALFPT----RSATSVLVGEPTTSPISS 1157

Query: 462  NSTTSADVTGSSASYPEGVNASVLTQFSD----STVQSGGSHTALGDRSYSESSSTSSSE 517
             ST +  + GS+ +   G++    T +S      T  S  S T+ G    SE S+TS S 
Sbjct: 1158 GSTETTALPGSTTT--AGLSEKSTTFYSSPRSPDTTLSPASTTSSG---VSEESTTSHSR 1212

Query: 518  --SLNSSAPRGERSIAGISYGQVRGTAIEQRT----SSDHTDHTYL---SSTF--TKGER 566
              S +++A  G  ++ G+S       +    T    S   T  + L   S+TF  + G  
Sbjct: 1213 PGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGST 1272

Query: 567  ALLSITDNSSSSDIVESSTSYIKISNSSHSEYSSFF------HAQTERSNISSYDGEYAQ 620
                + DN+++S ++E+ST     + S H+  S          + T +S  SS D   A 
Sbjct: 1273 ETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAP 1332

Query: 621  PSTESPVLHTSNL----PSYTPTINMPNTSVVL------------------------DTD 652
            P+T S  +  S      PS TPT +   +S  L                         T 
Sbjct: 1333 PTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTT 1392

Query: 653  AEFVSDSSSSSSS----------SSSSSSSGPPLPLPSVSQSHHLFSSILPSTRASVHLL 702
            +  V +S++  SS           SS++S        S S + H  SS  P +  S  + 
Sbjct: 1393 SGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISS--PPSTTSALVE 1450

Query: 703  KSTSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQSSSTPVLPRARETPVTSFQTST 762
            + TS  S+P S + +  P S TTS  +  S +  + P ++    LP A  T  TS + + 
Sbjct: 1451 EPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLP-AHFT--TSGRIAE 1507

Query: 763  MTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTES 822
             T+F     S +T    + +TP      T   +  LV  PT  T  ++ +         S
Sbjct: 1508 STTFYISPGSMETTLASTATTPGLSAKSTILYTSDLVGEPT--TFYISPSPTYTTLFPAS 1565

Query: 823  STEQTLPATSTNLAQMSPTFTTTILKTSQPLMTTPGT 859
            S+   L   ST     SP+FT+TI+ T       P T
Sbjct: 1566 SSTSGLTEESTTF-HTSPSFTSTIVSTESLETLAPET 1601


>gi|239754668 PREDICTED: mucin 12 [Homo sapiens]
          Length = 1952

 Score =  116 bits (290), Expect = 2e-25
 Identities = 244/1021 (23%), Positives = 386/1021 (37%), Gaps = 163/1021 (15%)

Query: 91   TQRGPSGRAPRGGSADAAWKHWPESN---------TEAHVENITFYQNQED------FST 135
            T   P+G   R G +   +  WP SN         T A VE  T              S 
Sbjct: 681  TTLSPAGSTTRQGES-TTFHSWPSSNDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISA 739

Query: 136  VSSKEGVMVQTSGKSHAASDAPENLTLL-AETADARGRSGSSSRTNFT----ILPVGYSL 190
             S+  G +V+ S   H++  + + +    ++T   RG   ++S ++ T      P   S 
Sbjct: 740  RSTTSG-LVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSA 798

Query: 191  EIATALTSQSGNLASESLHLPSSSS---EFDERIAAFQTKSGTASEMGTERAMGLSEEWT 247
             +    +  S   ++ + H P SS+     +E IA+  ++  T + +   R+       +
Sbjct: 799  LVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESIASHSSQDATGTIVLPARSTN-----S 853

Query: 248  VHSQEATTSAWSPSFLPALEM-GELTTPSRKRNSSGPDLSWLHFYRTAASSPLLDLSSSS 306
            V   E+TTS  S   +    + G  TTP     S+         + ++  SP   LS +S
Sbjct: 854  VLLGESTTSPISSGSMETTALPGSTTTPGLSERSTT--------FHSSPRSPATTLSPAS 905

Query: 307  ESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVSKTEGFPKDSRIA 366
             ++  ++  +    S    T T    T F D                + T G    SR +
Sbjct: 906  TTSSGVSEESTTSHSRPGSTHT----TAFPDS---------------TTTPGL---SRHS 943

Query: 367  TTSSSVLLSPSAVESR-----RNSRVTGNPGDEEFIEPSTENEFGLTSLRWQNDSPTFGE 421
            TTS S   SP + ++        + + G P        STE     T+L     + T G 
Sbjct: 944  TTSHS---SPGSTDTTLLPASTTTXLVGEPTTSPISSGSTET----TAL--PGSTTTAG- 993

Query: 422  HQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADVTGSS--ASYPEG 479
              L+  S     SP S   T+S +         T+  +   STTS    GS+   ++P  
Sbjct: 994  --LSEKSTTFYSSPRSPDTTLSPA-------STTSSGVSEESTTSHSRPGSTHTTAFPGS 1044

Query: 480  VNASVLTQFSDSTVQSGGS-HTALGDRSYSESSSTSSSESLNSSAPRGERSIAG---ISY 535
                 ++Q S ++  S GS  T L  RS + SS    S + +S     E ++      + 
Sbjct: 1045 TTMPGVSQESTASHSSPGSTDTTLSPRSTTASSLGPESTTFHSGPGSTETTLLPDNTTAS 1104

Query: 536  GQVRG-TAIEQRTSSDHTDHTYLSSTFTKGERALLSITDNSSSSDIVESSTS--YIKISN 592
            G +   T +   T S  T  +   ST  +GE        +S  +     +T+  ++++S 
Sbjct: 1105 GLLEASTPVHSSTGSPRTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELST 1164

Query: 593  SSHSEYSSFFHAQTERSNISSYDGEYAQPSTESPVLHTSNL-PSYTPTINMPNTSVVLDT 651
            +SH   SS     T  S  S+  G     S ES  +H+S + P+ TP+     TS +++ 
Sbjct: 1165 TSHGSPSSI--PTTHFSASSTTFGR----SEESTTVHSSPVAPATTPSPARSTTSGLVEE 1218

Query: 652  DAEFVSDSSSSSSS---SSSSSSSGPPLPLPSVSQSHHLFSSILPSTRASVHLLKSTSDA 708
               + S   S+ +     SS++S        S S + H  SS  P +  S  + + TS  
Sbjct: 1219 STAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISS--PPSTTSALVEEPTSYH 1276

Query: 709  STPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQSSSTPVLP-----RARETPVTSFQTSTM 763
            S+P S + +  P S TTS  +  S +  + P ++    LP       R    T+F  S  
Sbjct: 1277 SSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYISPG 1336

Query: 764  TSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLP-PSLTES 822
            +   T+  ++ T  L ++ST     + + S+SP     P   T +  +  P    S  ES
Sbjct: 1337 SMETTLASTATTPGLSAKST----ILYSSSRSPDQTLSPASMTSSSISGEPTSLYSQAES 1392

Query: 823  STEQTLPA--TSTNLAQMSPTFTTTILKTSQPLMTTPGTLSSTASLVTGPIAVQTTAGKQ 880
            +     PA  T++ L+Q S TF +    T   L     T SS A   T P    +  G  
Sbjct: 1393 THTTAFPASTTTSGLSQESTTFHSKPGSTETTLSPGSITTSSFAQEFTTP---HSQPGSA 1449

Query: 881  LSLTHP-EILVPQISTEGGI------STERNRVIVDATTGLIPLTSVP-----------T 922
            LS   P    VP +S E         STE        T  +    S P            
Sbjct: 1450 LSTVSPASTTVPGLSEESTTFYSSPGSTETTAFSHSNTMSIHSQQSTPFPDSPGFTHTVL 1509

Query: 923  SAKEMTTKLG-VTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSATFAVQSS-------- 973
             A   TT +G  +  +  +S + GT+P P     STA DL  +  TF +  S        
Sbjct: 1510 PATLTTTDIGQESTAFHSSSDATGTTPLPAR---STASDLVGEPTTFYISPSPTYTTLFP 1566

Query: 974  --------TQSPTTVSSSASVNSCAVN----PCLHNGECVADNTSRGYHCRCPPSWQGDD 1021
                    T+  TT  +S S  S  V+      L  G C       G  C CP  + G  
Sbjct: 1567 ASSSTSGLTEESTTFHTSPSFTSTIVSTESLETLAPGLCQEGQIWNGKQCVCPQGYVGYQ 1626

Query: 1022 C 1022
            C
Sbjct: 1627 C 1627



 Score =  102 bits (254), Expect = 3e-21
 Identities = 223/952 (23%), Positives = 354/952 (37%), Gaps = 137/952 (14%)

Query: 113  PESNTEAHVENITFYQNQEDFSTVSSKEGVMVQTSGKSHAASDAPENLTLLAETADARGR 172
            P   T A V+  T Y +    ST ++       T G S  ++    +    A T     R
Sbjct: 355  PSGTTSAFVKLSTTYHSSPS-STPTTHFSASSTTLGHSEESTPVHSSPVATATTPPP-AR 412

Query: 173  SGSSSRTNFTILPVGYSLEIATALTSQSGNLASESLHLPSSS--SEFDERIAAFQ----- 225
            S +S             +E +TA     G+  ++++H P SS  S   E  A F      
Sbjct: 413  SATSGH-----------VEESTAYHRSPGS--TQTMHFPESSTTSGHSEESATFHGSTTH 459

Query: 226  ----TKSGTASEMGTERAMGLSEEWTVH----------SQEATTSAWSPSFLPALEMGEL 271
                T S TA+   T     L    T H          S+E+  S  SP  +    +   
Sbjct: 460  TKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAG 519

Query: 272  TTPSRKRNSSGPDLSWLHFYRTAASSPLLDLSSSSESTEK--LNNSTGLQSSSVSQTKTM 329
            +TPS     S P         +  SS  ++ ++   ST K  L+  +    SS     T 
Sbjct: 520  STPSVLVGDSTP---------SPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTT 570

Query: 330  HVATVFTDGGPRTLRSLTVSLGPVSKTEGFPKDSRIATTSSSVLLSPSAVESRRNSRVTG 389
            H+    T  G     + + S    + T  FP  + +   S     S S   S   +  T 
Sbjct: 571  HLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHS---SPGPTDTTL 627

Query: 390  NPGDEEFIEPSTE-----NEFGLTSLRWQNDSPTFGEHQLASSSEVQNGSPMSQTETVSR 444
            +PG         E     +  G T      D+ T     L  +S   + S  S   T+S 
Sbjct: 628  SPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASG--LLEASMPVHSSTRSPHTTLSP 685

Query: 445  SVAPMRGGEITAH--WLLTNSTTSADVTGSSASYPEGVNASVLTQFSDSTVQSGGSHTAL 502
            + +  R GE T    W  +N T  A  T +SA             F + +  S GS +++
Sbjct: 686  AGSTTRQGESTTFHSWPSSNDTRPAPPTTTSA-------------FVEPSTTSHGSPSSI 732

Query: 503  GDRSYSESSSTSS---SESLNSSAPRGERSIAGISYGQVRGTAIEQRTSSDHTDHTYLSS 559
                 S  S+TS      +   S+P   +++         G   E  TS   T HT  S+
Sbjct: 733  PTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSA 792

Query: 560  TFTKGERALLSITDNSSSSDIVESSTSYIKISNSS---HSEYSSFFHAQTERSNISSYDG 616
                           S++S +VE  TSY     S+   H   SS    ++E S I+S+  
Sbjct: 793  P--------------STTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEES-IASHSS 837

Query: 617  EYAQPSTESPVLHTSNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPL 676
            + A  +   P   T+++     T + P +S  ++T A   S ++   S  S++  S P  
Sbjct: 838  QDATGTIVLPARSTNSVLLGESTTS-PISSGSMETTALPGSTTTPGLSERSTTFHSSPRS 896

Query: 677  PLPSVSQSHHLFSSILPSTRASVHLLKSTSDASTPWSSSPSPLPVSLTTSTSAPLSVSQT 736
            P  ++S +    S +   +  S     ST   + P S++   L    TTS S+P S   T
Sbjct: 897  PATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTT 956

Query: 737  TLPQSSSTPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSP 796
             LP S++T ++     +P++S  T T      +  S+ TA L  +ST       +   + 
Sbjct: 957  LLPASTTTXLVGEPTTSPISSGSTET----TALPGSTTTAGLSEKSTTFYSSPRSPDTTL 1012

Query: 797  SLVSLPTESTKAVTTNSPLPPSLTESST---EQTLPATS--TNLAQMSPTFTTTILKTSQ 851
            S  S  +      +T S   P  T ++      T+P  S  +  +  SP  T T   T  
Sbjct: 1013 SPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDT---TLS 1069

Query: 852  PLMTTPGTLS-STASLVTGPIAVQTTAGKQLSLTHPEILVPQISTEGGISTERNRVIVDA 910
            P  TT  +L   + +  +GP + +TT            L+P  +T  G+        V +
Sbjct: 1070 PRSTTASSLGPESTTFHSGPGSTETT------------LLPDNTTASGLLEASTP--VHS 1115

Query: 911  TTGLIPLTSVPTSAKEMTTKLGVTAEYSPASRSLGTSPSPQTTV-----VSTAEDLAPKS 965
            +TG    T  P  +   TT+ G +  +     S  T P+P TT      +ST    +P S
Sbjct: 1116 STGSPRTTLSPAGS---TTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSS 1172

Query: 966  ---ATFAVQSST----QSPTTVSSSASVNSCAVNPCLHNGECVADNTSRGYH 1010
                 F+  S+T    +  TTV SS    +   +P       + +  S  YH
Sbjct: 1173 IPTTHFSASSTTFGRSEESTTVHSSPVAPATTPSPARSTTSGLVEE-STAYH 1223



 Score = 80.1 bits (196), Expect = 1e-14
 Identities = 176/773 (22%), Positives = 279/773 (36%), Gaps = 140/773 (18%)

Query: 276 RKRNSSGPDLSWL----HFYRTAASSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHV 331
           R+  SS PD+S L    H       S     S  + ST  +N S G  ++S S   +   
Sbjct: 52  RQEVSSSPDVSELTATKHEETVINHSTFSGFSQITGST--VNTSIGGNTTSASTPSSSDP 109

Query: 332 ATVFTDGGPRTLRSLTVSLGPVSKTEGFPKDSRIATTSSSVLLSPSAVESRRNSRVTGNP 391
            T F+D G     S+T   G  + T+ F   S  +  S    +S S   +   +    + 
Sbjct: 110 FTTFSDYGV----SVTFITGSTA-TKHFLDSSTNSGHSEESTVSHSGPGATGTTLFPSHS 164

Query: 392 GDEEFI-EPSTE--NEFGLTSLRWQNDSPTFGEHQLASSSEVQNGSPMSQTETVSRSVAP 448
               F+ EP T       + +      + T G   L+  S     SP S   T+S    P
Sbjct: 165 ATSVFVGEPKTSPITSASMETTALPGSTTTAG---LSEKSTTFYSSPRSPDRTLS----P 217

Query: 449 MRGGEITAHWLLTNSTTSADVTGSSASYPEGVNASVLTQFSDSTVQSGGSHTALGDRSYS 508
            R             TTS+ V+  S +       +    F DST   G S  +    S  
Sbjct: 218 AR-------------TTSSGVSEKSTTSHSRPGPTHTIAFPDSTTMPGVSQESTASHSIP 264

Query: 509 ESSSTSSSESLNSSAPRG-ERSIAGISYGQVR----------------GTAIEQRTSSDH 551
            S+ T+ S    + +  G E +    S G  +                 T +   T S H
Sbjct: 265 GSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEASTPVHSSTGSPH 324

Query: 552 TDHTYLSSTFTKGERALLSITDNSSSSDIVESST--SYIKISNSSHSEYSSFFHAQTERS 609
           T  +  SST  +GE        +S  +    S T  +++K+S + HS  SS        S
Sbjct: 325 TTLSPASSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSAS 384

Query: 610 NISSYDGEYAQPSTESPVLHTS--------------------NLPSYTPTINMPNTSVVL 649
           + +    E + P   SPV   +                      P  T T++ P +S   
Sbjct: 385 STTLGHSEESTPVHSSPVATATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPESSTTS 444

Query: 650 DTDAEFVSDSSSSSSSSSSSSSSGPPL-------PLPSVSQSHHLFSSILPSTRASVHLL 702
               E  +   S++ + SS+ S+   L        L S   +H   SS +          
Sbjct: 445 GHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESKAS 504

Query: 703 KSTSDAST----PWSSSPSPLPVSLTTSTSAPLSVSQTTLPQSSSTPVLPRARETPVTSF 758
            S+ DA      P  S+PS L    T S  +  S+  T LP S++ P L        T+F
Sbjct: 505 HSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPGLSEKS----TTF 560

Query: 759 QTSTMTSFMTMLHSSQTADLKSQ--STPHQEKVITESKS-PSLVSLPTESTKAVTTNSPL 815
            +S  +   T L +S T+   S+  +T H     T + + P   ++P  S ++  ++S  
Sbjct: 561 YSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSP 620

Query: 816 PPSLTESSTEQTLPATSTNLAQMSPTFTTTILKTSQPLMTTPGTLSSTASLVTGPIAVQT 875
            P      T+ TL   ST  + + P +TT          + PG+  +T            
Sbjct: 621 GP------TDTTLSPGSTTASSLGPEYTT--------FHSRPGSTETT------------ 654

Query: 876 TAGKQLSLTHPEILVPQISTEGGISTERNRVIVDATTGLIPLTSVPTSAKEMTTKLGVTA 935
                        L+P  +T  G+  E +  +  +T    P T++  S    TT+ G + 
Sbjct: 655 -------------LLPDNTTASGL-LEASMPVHSSTRS--PHTTL--SPAGSTTRQGEST 696

Query: 936 EYSPASRSLGTSPSPQTTVVSTAEDLAPKSATFAVQSSTQSPTTVSSSASVNS 988
            +     S  T P+P TT  +  E      +T +  S +  PTT  S+ S  S
Sbjct: 697 TFHSWPSSNDTRPAPPTTTSAFVE-----PSTTSHGSPSSIPTTHISARSTTS 744


>gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]
          Length = 5765

 Score =  107 bits (267), Expect = 8e-23
 Identities = 188/833 (22%), Positives = 313/833 (37%), Gaps = 117/833 (14%)

Query: 250  SQEATTSAWSPSFLPALE--MGELTTPSRKRNSSGPDLSWLHFYRTAASSPLLDLSSSSE 307
            S  AT+S   PS  P     + ELTT +    S+G   S      T  ++P   + +S  
Sbjct: 4233 STPATSSTAMPSSTPGTTWILTELTTTATTTASTG---STATPSSTPGTAPPPKVLTSPA 4289

Query: 308  STEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLT-VSLGPVSKTEGFPKDSRIA 366
            +T    +S    SSS     T+ V T  +     T  S+T +    +  T   P+ +   
Sbjct: 4290 TTPTATSSKATSSSSPRTATTLPVLT--STATKSTATSVTPIPSSTLGTTGTLPEQTTTP 4347

Query: 367  TTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQNDSPTFGEHQLAS 426
              + S +   S  E+   S V            ST          W        E   A+
Sbjct: 4348 VATMSTIHPSSTPETTHTSTVLTTKATTTRATSSTSTPSSTPGTTW-----ILTELTTAA 4402

Query: 427  SSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADVTGSSAS----------- 475
            ++    G   + + T   +            W+LT  TT+A  T S+ S           
Sbjct: 4403 TTTAATGPTATPSSTPGTT------------WILTELTTTATTTASTGSTATPSSTPGTT 4450

Query: 476  --YPEGVNASVLTQFSDSTVQSGGSHTALGDRSYSESSST---SSSESLNSSAPRGERSI 530
                E    + +T  + ST  +  +    G    S +++T   +SS++  SS+P    ++
Sbjct: 4451 WILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPSSSPGTATAL 4510

Query: 531  AGISYGQVRGTAIEQR---TSSDHTDHTYLSSTFTKGERALLSITDNSSSSDIVESSTSY 587
              +       TA       +SS  T  T LS T T    A +S    SS+ + V +ST  
Sbjct: 4511 PALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTP--TATMSTATPSSTPETVHTST-- 4566

Query: 588  IKISNSSHSEYSSFFHAQTERSNISSYDGEYAQPSTESPVLHTSNLPSYTPT------IN 641
                              T  +  +   G  A PS+     HT+ +P+ T T       +
Sbjct: 4567 ----------------VLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSS 4610

Query: 642  MPNTSVVLDTDAEFVSDSSSSSSSS-SSSSSSGPPLPLPSVSQSHHLFSSILPS--TRAS 698
             P T++   T   ++S +++ ++++ ++S S+  P  +P  + +  + ++   +  T + 
Sbjct: 4611 SPGTAL---TPPVWISTTTTPTTTTPTTSGSTVTPSSIPGTTHTARVLTTTTTTVATGSM 4667

Query: 699  VHLLKSTSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTT--LPQSSSTPVLPRARETPVT 756
                 ST  + TP S + +   ++ T ST+ P S   TT   P  +ST   P A  +  T
Sbjct: 4668 ATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPITPVLTSTATTPAATSSKAT 4727

Query: 757  SFQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVI-TESKSPSLVSLPTESTKAVTTNSPL 815
            S  +    + + +L S+ T    +  TP     + T    P+  + P  +   + T+S  
Sbjct: 4728 SSSSPRTATTLPVLTSTATKSTATSFTPIPSSTLWTTWTVPAQTTTPMSTMSTIHTSST- 4786

Query: 816  PPSLTESSTEQTLPATSTNLAQMSPTFTTTILKTS--QPLMTTPGTLSSTASLVTGPIAV 873
             P  T +ST  T  AT T     + T ++T+  T     L TT  T ++T S  T    +
Sbjct: 4787 -PETTHTSTVLTTTATMTRATNSTATPSSTLGTTRILTELTTTATTTAATGSTAT----L 4841

Query: 874  QTTAGKQLSLTHPEILVPQISTEGGISTERNRVIVDATTGLIPLTSVPTSAKEMTTKLGV 933
             +T G    LT P  +   +   G  +T        +T G      V T+   M T    
Sbjct: 4842 SSTPGTTWILTEPSTIATVMVPTGSTAT------ASSTLGTAHTPKVVTTMATMPT---A 4892

Query: 934  TAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSATFAVQSS---TQSPTTVSSSASVNSC- 989
            TA   P+S ++GT+ +P     S      P  +   V SS   T  PT   SS     C 
Sbjct: 4893 TASTVPSSSTVGTTRTPAVLPSS-----LPTFSVSTVSSSVLTTLRPTGFPSSHFSTPCF 4947

Query: 990  --AVNPCLHNGECVADNTSRG---YHCRCPPSWQGDDCSVD--VNECLSNPCP 1035
              A       GE + + T R    ++  C        C +D     C ++P P
Sbjct: 4948 CRAFGQFFSPGEVIYNKTDRAGCHFYAVC-----NQHCDIDRFQGACPTSPPP 4995



 Score = 97.4 bits (241), Expect = 8e-20
 Identities = 230/935 (24%), Positives = 360/935 (38%), Gaps = 150/935 (16%)

Query: 146  TSGKSHAASDAPENLTLLAETADARGRSGSSSRTNFT--ILPVGYSLEIATALTSQSGNL 203
            T   S   S  P +LT  A T  A G + + S T  T  I PV  +     A TS +   
Sbjct: 2679 TPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTP 2738

Query: 204  ASE--SLHLP--------------SSSSEFDERIAAFQTKSGTASEMG-TERAMGLSEEW 246
            +S   + H P              S SS    R A     SGT      TE + G S   
Sbjct: 2739 SSALGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTS--- 2795

Query: 247  TVHSQEATTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASSPLLDLSSSS 306
              H+  ATT     S  PAL       PS +   S P         T A+S     ++++
Sbjct: 2796 --HTPAATTGTTQHS-TPALSSPH---PSSRTTESPPSPGTTTPGHTRATSR----TTAT 2845

Query: 307  ESTEKLNNSTGLQSSSVSQTKTMHVATVFTDG-GPRTLRSLTVSLG-PVSKTEG--FPKD 362
             +  K   ST L SS  S      + TV T G  P+   S  +    P+    G  F   
Sbjct: 2846 ATPSKTRTSTLLPSSPTSAP----ITTVVTMGCEPQCAWSEWLDYSYPMPGPSGGDFDTY 2901

Query: 363  SRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQNDSPTFGEH 422
            S I     +V   P  +E R  ++  G P  E         +FGL       +    G+ 
Sbjct: 2902 SNIRAAGGAVCEQPLGLECRAQAQ-PGVPLRELGQVVECSLDFGLVC----RNREQVGKF 2956

Query: 423  QLASSSEVQ----NGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADVTGSSASYPE 478
            ++  + E++    N      T   S +  P      T  W+LT  TT+A  T ++ S   
Sbjct: 2957 KMCFNYEIRVFCCNYGHCPSTPATSSTATPSSTPGTT--WILTEQTTAATTTATTGS--- 3011

Query: 479  GVNASVLTQFSDSTVQSGGSHTALGDRSYSESSSTSSSESLNSSAPRGERSIAGISYGQV 538
                   T    ST  +      L   S + + + +SS++ +SS+PR   ++  ++    
Sbjct: 3012 -------TAIPSSTPGTAPPPKVL--TSTATTPTATSSKATSSSSPRTATTLPVLTSTAT 3062

Query: 539  RGTAIEQRTSSDHTDHTYLSSTFTKGERALLSITDNSSSSDIVESSTSYIKISNSSHSEY 598
            + TA    TS        L +T T  E+   + T  ++ S I  SST     +++  +  
Sbjct: 3063 KSTA----TSFTPIPSFTLGTTGTLPEQ---TTTPMATMSTIHPSSTPETTHTSTVLTTK 3115

Query: 599  SSFFHAQTERSNISSYDGE--YAQPSTESPVLHTSNLPSYTPTINMPNTSVVL---DTDA 653
            ++   A +  S  SS  G        T +     +  P+ TP+ + P T+ +L    T A
Sbjct: 3116 ATTTRATSSMSTPSSTPGTTWILTELTTAATTTAATGPTATPS-STPGTTWILTEPSTTA 3174

Query: 654  EFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSIL-----PSTRASVHLLKSTSDA 708
                 + S++++SS+ +++G    L S + +  + SS       P T  ++  L+ST  A
Sbjct: 3175 TVTVPTGSTATASSTRATAGTLKVLTSTATTPTVISSRATPSSSPGTATALPALRST--A 3232

Query: 709  STPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQSSSTPVLPRARETPVTSFQTSTMTSFMT 768
            +TP ++S + +P S  +  +A   +SQTT P ++ +   P +    V +    T T+  T
Sbjct: 3233 TTPTATSVTAIPSS--SLGTAWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTTTTT 3290

Query: 769  MLHSSQTADLKSQSTPHQEKV---------ITESKSPSLVSLP--------TESTKAVTT 811
                S      +  T H  KV          T S SP     P        T +T+  T 
Sbjct: 3291 RATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTV 3350

Query: 812  NSPLPPSLTESSTEQTL------------PATSTNLAQMSPTFTTTIL------KTSQPL 853
                 P  T ++T  T             P++ST  +   P+ TTT         T+ P 
Sbjct: 3351 TPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNP- 3409

Query: 854  MTTPGT------LSSTASLVTGPIAVQTTA--GKQLSLTHPEILVPQISTEGGISTERNR 905
             +TPGT      L++TA   T P A  +T      L  TH   +    +T  G S   + 
Sbjct: 3410 SSTPGTTPIPPVLTTTA---TTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLPPSS 3466

Query: 906  ------VIVDATTGLI---------PLTSVPTSAKEMTTKLGVTAEYSP--ASRSLGTSP 948
                      AT+G++          +TS   +A   TT+    A  SP  +SR+  + P
Sbjct: 3467 PHTVRTAWTSATSGILGTTHITEPSTVTSHTPAATTSTTQHSTPALSSPHPSSRTTESPP 3526

Query: 949  SPQTTVVSTAEDLAPKSATFAVQSSTQSPTTVSSS 983
            SP TT        +  +AT A  S T++ T + SS
Sbjct: 3527 SPGTTTPGHTRGTSRTTAT-ATPSKTRTSTLLPSS 3560



 Score = 96.3 bits (238), Expect = 2e-19
 Identities = 111/401 (27%), Positives = 169/401 (42%), Gaps = 40/401 (9%)

Query: 621  PSTESPVLHTSNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPS 680
            PST  P   ++ +PS TP      T   L T A   + + S+++ SS+  ++ PP  L S
Sbjct: 4232 PST--PATSSTAMPSSTPGTTWILTE--LTTTATTTASTGSTATPSSTPGTAPPPKVLTS 4287

Query: 681  VSQSHHLFSSILPSTRASVHLLKSTSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQ 740
                        P+T  +    K+TS +S+P +++  P+  S  T ++A    S T +P 
Sbjct: 4288 ------------PATTPTATSSKATS-SSSPRTATTLPVLTSTATKSTA---TSVTPIPS 4331

Query: 741  SS--STPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSL 798
            S+  +T  LP    TPV +  T   +S     H+S     K+ +T       T S +P  
Sbjct: 4332 STLGTTGTLPEQTTTPVATMSTIHPSSTPETTHTSTVLTTKATTTRATSSTSTPSSTPGT 4391

Query: 799  VSLPTESTKAVTTNSPLPPSLTESSTEQTLPATSTNLAQMSPTFTTTIL--KTSQPLMTT 856
              + TE T A TT +   P+ T SST    P T+  L +++ T TTT     T+ P  T 
Sbjct: 4392 TWILTELTTAATTTAATGPTATPSST----PGTTWILTELTTTATTTASTGSTATPSSTP 4447

Query: 857  PGTLSSTASLVTGPIAVQTTAGKQLSLTHPEILVPQISTEGGISTERNRVIVDATTGLIP 916
              T   T    T  + V T +    S T      P +ST     T  +     AT    P
Sbjct: 4448 GTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSS---KATPSSSP 4504

Query: 917  --LTSVPTSAKEMTTKLGVTAEYSPASRSLGTS---PSPQTTVVSTAEDLAPKSATFAVQ 971
               T++P      TT    +    P+S SLGT+    S  TT  +T     P S    V 
Sbjct: 4505 GTATALPALRSTATTPTATSFTAIPSS-SLGTTWTRLSQTTTPTATMSTATPSSTPETVH 4563

Query: 972  SS---TQSPTTVSSSASVNSCAVNPCLHNGECVADNTSRGY 1009
            +S   T + TT  ++ SV + +  P   +   V   T+ G+
Sbjct: 4564 TSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGF 4604



 Score = 84.0 bits (206), Expect = 9e-16
 Identities = 197/815 (24%), Positives = 311/815 (38%), Gaps = 127/815 (15%)

Query: 146  TSGKSHAASDAPENLTLLAETADARGRSGSSSRTNFT--ILPVGYSLEIATALTSQSGNL 203
            T   S   S  P +LT  A T  A G + + S T  T  I PV  +     A TS +   
Sbjct: 3379 TPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTP 3438

Query: 204  ASE--SLHLPS--------------SSSEFDERIAAFQTKSGTASEMGTERAMGLSEEWT 247
            +S   + H P                SS    R A     S T+  +GT     ++E  T
Sbjct: 3439 SSALGTTHTPPVPNTTATTHGRSLPPSSPHTVRTA---WTSATSGILGTTH---ITEPST 3492

Query: 248  V--HSQEATTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASSPLLDLSSS 305
            V  H+  ATTS    S  PAL       PS +   S P         T  +S     +++
Sbjct: 3493 VTSHTPAATTSTTQHS-TPALSSPH---PSSRTTESPPSPGTTTPGHTRGTSR----TTA 3544

Query: 306  SESTEKLNNSTGLQSSSVSQTKTMHVATVFTDG-GPRTLRSLTVSLG-PVSKTEG--FPK 361
            + +  K   ST L SS  S      + TV T G  P+   S  +    P+    G  F  
Sbjct: 3545 TATPSKTRTSTLLPSSPTSAP----ITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDT 3600

Query: 362  DSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQNDSPTFGE 421
             S I     +V   P  +E R  ++  G P  E         +FGL       +    G+
Sbjct: 3601 YSNIRAAGGAVCEQPLGLECRAQAQ-PGVPLRELGQVVECSLDFGLVC----RNREQVGK 3655

Query: 422  HQLASSSEVQ----NGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADVTGSSAS-- 475
             ++  + E++    N      T   S +  P      T  W+LT  TT+A  T S+ S  
Sbjct: 3656 FKMCFNYEIRVFCCNYGHCPSTPATSSTATPSSTPGTT--WILTKLTTTATTTESTGSTA 3713

Query: 476  -----------YPEGVNASVLTQFSDSTVQSGGSHTALGDRSYSESSST---SSSESLNS 521
                         E    + +T  + ST  +  +    G    S +++T   +SS++   
Sbjct: 3714 TPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPF 3773

Query: 522  SAPRGERSIAGISYGQVRGTAIEQRTSSDHTDHTYLSSTFTKGERALLSITDNSSSSDIV 581
            S+P    ++  +       TA    TS      + L +T+T   R   + T  ++ S   
Sbjct: 3774 SSPGTATALPALRSTATTPTA----TSFTAIPSSSLGTTWT---RLSQTTTPTATMSTAT 3826

Query: 582  ESSTSYIKISNSSHSEYSSFFHAQTERSNISSYDGEYAQPSTESPVLHTSNLPSYTP--- 638
             SST       ++H+       A T R+      G  A PS+     HT+ +P+ T    
Sbjct: 3827 PSST-----PETAHTSTVLTTTATTTRAT-----GSVATPSSTPGTAHTTKVPTTTTTGF 3876

Query: 639  TINMPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSILPSTRAS 698
            T+   ++     T   ++S +++ ++S S+ + S  P        +H    ++L +T  +
Sbjct: 3877 TVTPSSSPGTARTPPVWISTTTTPTTSGSTVTPSSVP------GTTH--TPTVLTTTTTT 3928

Query: 699  VHLLKSTSDASTPWSSS-PSPLPVSLTTSTSAPLSVSQTTLPQSSS-----TPVLPRARE 752
            V    +T   +TP SS+  S  P SL T+ +   +   TT P S+       PVL     
Sbjct: 3929 V----ATGSMATPSSSTQTSGTPPSLITTATTITATGSTTNPSSTPGTTPIPPVLTTTAT 3984

Query: 753  TPVTSFQTSTMTSFMTMLH------SSQTADLKSQSTPHQEKVITESKSPSLVSLPTEST 806
            TP  +  T T +S +   H      ++ T   +S S      V T   S +  +L T   
Sbjct: 3985 TPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHI 4044

Query: 807  KAVTTNSPLPPSLTESSTEQTLPATSTNLAQMSPTFTTTILKTSQPLMTTPGTLSSTASL 866
               +T +   P+ T  +T+ + PA    L+   P+  TT    S P  TTPG  ++T+  
Sbjct: 4045 TEPSTGTSHTPAATTGTTQHSTPA----LSSPHPSSRTTESPPS-PGTTTPGHTTATS-- 4097

Query: 867  VTGPIAVQTTAGKQLSLTHPEILVPQISTEGGIST 901
                   +TTA    S T    L+P   T   I+T
Sbjct: 4098 -------RTTATATPSKTRTSTLLPSSPTSAPITT 4125



 Score = 82.4 bits (202), Expect = 3e-15
 Identities = 208/999 (20%), Positives = 357/999 (35%), Gaps = 142/999 (14%)

Query: 76   ATPGPSYRAPEPGAATQRGPSGRAPRGGSADAAWKHWPESNTEAHVENITFYQNQEDFST 135
            +TPG ++   EP        +   P G +A A       S+T A    +    +     T
Sbjct: 3159 STPGTTWILTEPSTTA----TVTVPTGSTATA-------SSTRATAGTLKVLTSTATTPT 3207

Query: 136  VSSKEGVMVQTSGKSHAASDAPENLTLLAETADARGRSGSSSRTNFTILPVGYSLEIATA 195
            V S       + G + A       L  L  TA       + + T+ T +P        T 
Sbjct: 3208 VISSRATPSSSPGTATA-------LPALRSTAT------TPTATSVTAIPSSSLGTAWTR 3254

Query: 196  LTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTASEMGTERAMGLSEEWTVHSQEATT 255
            L+  +   A+ S   PSS+ E         T + T    G+  A   S   T H+ +  T
Sbjct: 3255 LSQTTTPTATMSTATPSSTPETVHTSTVLTTTTTTTRATGSV-ATPSSTPGTAHTTKVPT 3313

Query: 256  -----------SAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASSPLLDLSS 304
                       S+   +  P + +   TTP+ + ++  P         T  ++ +L  ++
Sbjct: 3314 TTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPS----SIPGTTHTATVLTTTT 3369

Query: 305  SSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPV----SKTEGFP 360
            ++ +T  +   +    +S +       AT  T  G  T  S T    P+    + T   P
Sbjct: 3370 TTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTP 3429

Query: 361  KDSRIATTSSSVL----------------------LSPSAVESRRNSRVTGNPGDEEFIE 398
              +    T SS L                       SP  V +   S  +G  G     E
Sbjct: 3430 AATSSTVTPSSALGTTHTPPVPNTTATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITE 3489

Query: 399  PSTENEF--GLTSLRWQNDSPTFGEHQLASSSEVQNGSPMS----QTETVSRSVAPMRGG 452
            PST        T+   Q+ +P       +S +     SP +     T   SR+ A     
Sbjct: 3490 PSTVTSHTPAATTSTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRGTSRTTATATPS 3549

Query: 453  EITAHWLLTNSTTSADVTG--SSASYPEGVNASVLTQFSDSTVQSGGSHTALGDRSYSES 510
            +     LL +S TSA +T   ++   P+   +  L         SGG      +   +  
Sbjct: 3550 KTRTSTLLPSSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGG 3609

Query: 511  SSTSSSESLNSSAPRGERSIAGISYGQVRGTAIEQRTSSDHTDHTYLSSTFTKGERALLS 570
            +       L   A + +  +     GQV   +++      + +           E  +  
Sbjct: 3610 AVCEQPLGLECRA-QAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFC 3668

Query: 571  ITDNSSSSDIVESSTSYIKISNSSHSEYSSFFHAQTERSNISSYDGEYAQPSTESPVLHT 630
                   S    SST+    + SS    +      T  +  +   G  A PS+       
Sbjct: 3669 CNYGHCPSTPATSSTA----TPSSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTTWI 3724

Query: 631  SNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPP-----LPLPSVSQSH 685
               PS T T+ +P               + S++++SS+ +++G P        P+V+ S 
Sbjct: 3725 LTEPSTTATVTVP---------------TGSTATASSTQATAGTPHVSTTATTPTVTSSK 3769

Query: 686  HL-FSSILPSTRASVHLLKSTSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQSSST 744
               FSS  P T  ++  L+ST  A+TP ++S + +P S   +T   LS  QTT P ++ +
Sbjct: 3770 ATPFSS--PGTATALPALRST--ATTPTATSFTAIPSSSLGTTWTRLS--QTTTPTATMS 3823

Query: 745  PVLPRARETPVTSFQTSTMTSFMTMLHSSQTADLKSQS--TPHQEKV---------ITES 793
               P +  TP T+  ++ +T+  T   ++ +    S +  T H  KV         +T S
Sbjct: 3824 TATPSS--TPETAHTSTVLTTTATTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPS 3881

Query: 794  KSPSLVSLP----TESTKAVTTNSPLPPSLTESSTEQ--TLPATSTNLAQMS---PTFTT 844
             SP     P    + +T   T+ S + PS    +T     L  T+T +A  S   P+ +T
Sbjct: 3882 SSPGTARTPPVWISTTTTPTTSGSTVTPSSVPGTTHTPTVLTTTTTTVATGSMATPSSST 3941

Query: 845  TILKTSQPLMTTPGTLSSTASLVTGPIAVQTTAGKQL---SLTHPEILVPQISTEGGIST 901
                T   L+TT  T+++T S         TT    +   + T P      ++    + T
Sbjct: 3942 QTSGTPPSLITTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGT 4001

Query: 902  ERNRVIVDATTGLIPLTSVPTSAKEMTTK--------LGVTAEYSPASRSLGTSPSPQTT 953
                 + + T      +  P+S   + T         LG T    P   S GTS +P  T
Sbjct: 4002 THTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEP---STGTSHTPAAT 4058

Query: 954  VVSTAEDLAPKSATFAVQSSTQSPTTVSSSASVNSCAVN 992
              +T       S+      +T+SP +  ++   ++ A +
Sbjct: 4059 TGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATS 4097



 Score = 80.9 bits (198), Expect = 8e-15
 Identities = 103/379 (27%), Positives = 152/379 (40%), Gaps = 65/379 (17%)

Query: 621  PSTESPVLHTSNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPS 680
            PST  P   ++  PS TP      T     T A   + + S++  SS+  ++ PP  L S
Sbjct: 2975 PST--PATSSTATPSSTPGTTWILTEQT--TAATTTATTGSTAIPSSTPGTAPPPKVLTS 3030

Query: 681  VSQ-----SHHLFSSILPSTRASVHLLKSTSDASTPWSSSPSPLPVSLTTSTSAPLSVSQ 735
             +      S    SS  P T  ++ +L ST+  ST  S +P P   S T  T+  L   Q
Sbjct: 3031 TATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIP---SFTLGTTGTLP-EQ 3086

Query: 736  TTLPQSSSTPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKS 795
            TT P ++ + + P +  TP T+  ++ +T+  T   ++      S STP        S +
Sbjct: 3087 TTTPMATMSTIHPSS--TPETTHTSTVLTTKATTTRATS-----SMSTP--------SST 3131

Query: 796  PSLVSLPTESTKAVTTNSPLPPSLTESSTEQTLPATSTNLAQMSPTFTTTI----LKTSQ 851
            P    + TE T A TT +   P+ T SST    P T+  L + S T T T+      T+ 
Sbjct: 3132 PGTTWILTELTTAATTTAATGPTATPSST----PGTTWILTEPSTTATVTVPTGSTATAS 3187

Query: 852  PLMTTPGTLSSTASLVTGPIAVQTTAGKQLSLTHPEILVPQISTEGGISTERNRVIVDAT 911
                T GTL    S  T P  + + A                S+  G +T    +   AT
Sbjct: 3188 STRATAGTLKVLTSTATTPTVISSRATP--------------SSSPGTATALPALRSTAT 3233

Query: 912  TGLIPLTSVPTSAKEMTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSATFAVQ 971
            T                T   VTA  S +  +  T  S  TT  +T     P S    V 
Sbjct: 3234 T---------------PTATSVTAIPSSSLGTAWTRLSQTTTPTATMSTATPSSTPETVH 3278

Query: 972  SSTQSPTTVSSSASVNSCA 990
            +ST   TT +++ +  S A
Sbjct: 3279 TSTVLTTTTTTTRATGSVA 3297



 Score = 78.2 bits (191), Expect = 5e-14
 Identities = 94/390 (24%), Positives = 159/390 (40%), Gaps = 34/390 (8%)

Query: 617  EYAQPSTESPVLHTSNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPL 676
            E    +T +    ++ +PS TP    P   +         + S ++SSSS  ++++ P L
Sbjct: 2998 EQTTAATTTATTGSTAIPSSTPGTAPPPKVLTSTATTPTATSSKATSSSSPRTATTLPVL 3057

Query: 677  PLPSVSQSHHLFSSILPSTRASVHLL--KSTSDASTPWSSSPSPLPVSLTTSTSAPLSVS 734
               +   +   F+ I   T  +   L  ++T+  +T  +  PS  P +  TST      +
Sbjct: 3058 TSTATKSTATSFTPIPSFTLGTTGTLPEQTTTPMATMSTIHPSSTPETTHTSTVLTTKAT 3117

Query: 735  QTTLPQSSSTPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESK 794
             T    S STP       TP T++  + +T+  T   ++      S STP    ++TE  
Sbjct: 3118 TTRATSSMSTP-----SSTPGTTWILTELTTAATTTAATGPTATPS-STPGTTWILTEPS 3171

Query: 795  SPSLVSLPTEST-------------KAVTTNSPLPPSLTESSTEQTLPATSTNLAQMSPT 841
            + + V++PT ST             K +T+ +  P  ++  +T  + P T+T L  +  T
Sbjct: 3172 TTATVTVPTGSTATASSTRATAGTLKVLTSTATTPTVISSRATPSSSPGTATALPALRST 3231

Query: 842  FTT-TILKTSQPLMTTPGTLSSTASLVTGPIAVQTTAGKQLSLTHPEILVPQISTEGGIS 900
             TT T    +    ++ GT  +  S  T P A  +TA    S T   +    + T    +
Sbjct: 3232 ATTPTATSVTAIPSSSLGTAWTRLSQTTTPTATMSTATP--SSTPETVHTSTVLTTTTTT 3289

Query: 901  TERNRVIV--DATTGLIPLTSVPTSAKEMTTKLGVTAEYSPASRSLGTSP---SPQTTVV 955
            T     +    +T G    T VPT     TT  G TA  S +  +  T P   S  TT  
Sbjct: 3290 TRATGSVATPSSTPGTAHTTKVPT-----TTTTGFTATPSSSPGTALTPPVWISTTTTPT 3344

Query: 956  STAEDLAPKSATFAVQSSTQSPTTVSSSAS 985
            +    + P S      ++T   TT ++ A+
Sbjct: 3345 TRGSTVTPSSIPGTTHTATVLTTTTTTVAT 3374



 Score = 77.4 bits (189), Expect = 9e-14
 Identities = 102/406 (25%), Positives = 168/406 (41%), Gaps = 57/406 (14%)

Query: 620  QPSTES----PVLHTSNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPP 675
            +PST +    P   T+   S   T   P+ S    T    V+ S ++  SS  ++++ P 
Sbjct: 2470 EPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPT--VTSSKATPFSSPGTATALPA 2527

Query: 676  LPLPSVSQSHHLFSSILPSTRASV--HLLKSTSDASTPWSSSPSPLPVSLTTSTSAPLSV 733
            L   + + +   F++I  S+  +    L ++T+  +T  +++PS  P ++ TST    + 
Sbjct: 2528 LRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTA 2587

Query: 734  SQTTLPQSSSTPVLPRARETPVTSFQTSTMTSFMTMLHSSQTAD----------LKSQST 783
            + T    S +TP       TP T+  T  +T+  T   ++ ++           + + +T
Sbjct: 2588 TTTGATGSVATP-----SSTPGTAHTTKVLTTTTTGFTATPSSSPGTARTLPVWISTTTT 2642

Query: 784  PHQE-KVITESKSPSLVSLPTESTKAVTT--------------NSPLPPSLTESSTEQTL 828
            P      +T S  P     PT  T   TT               S  PPSLT ++T  T 
Sbjct: 2643 PTTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITA 2702

Query: 829  PATSTNLAQ------MSPTFTTTILKTSQPLMT-TPGTLSSTASLVTGPIAVQTTAGKQL 881
              ++TN +       + P  TTT    +    T TP +   T      P    TT G+ L
Sbjct: 2703 TGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSL 2762

Query: 882  SLTHPEILVPQ--ISTEGGISTERNRVIVDATTGLIPLTSVPTSAKEMTTKLGVTAEYSP 939
            S + P  +      +T G + T     I + +TG    TS   +A   TT+    A  SP
Sbjct: 2763 SPSSPHTVRTAWTSATSGTLGTTH---ITEPSTG----TSHTPAATTGTTQHSTPALSSP 2815

Query: 940  --ASRSLGTSPSPQTTVVSTAEDLAPKSATFAVQSSTQSPTTVSSS 983
              +SR+  + PSP TT        +  +AT A  S T++ T + SS
Sbjct: 2816 HPSSRTTESPPSPGTTTPGHTRATSRTTAT-ATPSKTRTSTLLPSS 2860



 Score = 74.3 bits (181), Expect = 7e-13
 Identities = 191/815 (23%), Positives = 305/815 (37%), Gaps = 121/815 (14%)

Query: 146  TSGKSHAASDAPENLTLLAETADARGRSGSSSRTNFT--ILPVGYSLEIATALTSQSGNL 203
            T   S   S  P +LT  A T  A G + + S T  T  I PV  +     A TS +   
Sbjct: 2122 TPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSNTVTP 2181

Query: 204  ASE--SLHLPS--------------SSSEFDERIAAFQTKSGTASEMGTERAMGLSEEWT 247
            +S   + H P                SS    R A     S T+  +GT     ++E  T
Sbjct: 2182 SSALGTTHTPPVPNTMATTHGRSLPPSSPHTVRTA---WTSATSGILGTTH---ITEPST 2235

Query: 248  V--HSQEATTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASSPLLDLSSS 305
            V  H+  ATT     S  PAL       PS +   S P         T A+S     +++
Sbjct: 2236 VTSHTLAATTGTTQHS-TPALSSPH---PSSRTTESPPSPGTTTPGHTTATSR----TTA 2287

Query: 306  SESTEKLNNSTGLQSSSVSQTKTMHVATVFTDG-GPRTLRSLTVSLG-PVSKTEG--FPK 361
            + +  K   ST L SS  S      + TV T G  P+   S  +    P+    G  F  
Sbjct: 2288 TATPSKTRTSTLLPSSPTSAP----ITTVVTMGCEPQCAWSEWLDYSYPMPGPSGGDFDT 2343

Query: 362  DSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQNDSPTFGE 421
             S I     +V   P  +E R  ++  G P  E         +FGL       +    G+
Sbjct: 2344 YSNIRAAGGAVCEQPLGLECRAQAQ-PGVPLRELGQVVECSLDFGLVC----RNREQVGK 2398

Query: 422  HQLASSSEVQ----NGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADVTGSSAS-- 475
             ++  + E++    N      T   S +  P      T  W+LT  TT+A  T S+ S  
Sbjct: 2399 FKMCFNYEIRVFCCNYGHCPSTPATSSTAMPSSTPGTT--WILTELTTTATTTESTGSTA 2456

Query: 476  -----------YPEGVNASVLTQFSDSTVQSGGSHTALGDRSYSESSST---SSSESLNS 521
                         E    + +T  + ST  +  +    G    S +++T   +SS++   
Sbjct: 2457 TPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPF 2516

Query: 522  SAPRGERSIAGISYGQVRGTAIEQR---TSSDHTDHTYLSSTFTKGERALLSITDNSSSS 578
            S+P    ++  +       TA       +SS  T  T LS T T    A +S    SS+ 
Sbjct: 2517 SSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTP--TATMSTATPSSTP 2574

Query: 579  DIVESST------SYIKISNSSHSEYSSFFHAQTERSNISSYDGEYAQPSTESPVLHTSN 632
            + V +ST      +    + S  +  S+   A T +   ++  G  A PS+      T  
Sbjct: 2575 ETVHTSTVLTTTATTTGATGSVATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGTART-- 2632

Query: 633  LPSYTPTINMP----------------NTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPL 676
            LP +  T   P                +T  VL T    V+  S ++ SSS+ +S  PP 
Sbjct: 2633 LPVWISTTTTPTTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPS 2692

Query: 677  PLPSVSQSHHLFSSILPSTRASVHLLKSTSDASTPWSSSPSPLPVSLTTSTSAPLSVSQT 736
                           L +T  ++    ST++ S+  +   +P+P  LTT+ + P + S T
Sbjct: 2693 ---------------LTTTATTITATGSTTNPSS--TPGTTPIPPVLTTTATTPAATSST 2735

Query: 737  TLPQSS--STPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESK 794
              P S+  +T   P    T  T  ++ + +S  T+  +  +A   +  T H  +  T + 
Sbjct: 2736 VTPSSALGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTS 2795

Query: 795  SPSLVSLPTESTKAVTTNSPLPPSLTESSTEQ---TLPATSTNLAQMSPTFTTTILKTSQ 851
                 +  T        +SP P S T  S      T P  +   ++ + T T +  +TS 
Sbjct: 2796 HTPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRATSRTTATATPSKTRTST 2855

Query: 852  PLMTTPGTLSSTASLVTGPIAVQTTAGKQLSLTHP 886
             L ++P T +   ++VT     Q    + L  ++P
Sbjct: 2856 LLPSSP-TSAPITTVVTMGCEPQCAWSEWLDYSYP 2889



 Score = 73.2 bits (178), Expect = 2e-12
 Identities = 115/471 (24%), Positives = 197/471 (41%), Gaps = 70/471 (14%)

Query: 555  TYLSSTFTKGERALLSITDNSSSSDIVESSTSYIKISNSSHSEYSSFF------HAQTER 608
            T  ++T + G  A  S T  ++      S+T+ + +   S +  SS        H  T  
Sbjct: 3701 TTATTTESTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTA 3760

Query: 609  SN---ISSYDGEYAQPSTES--PVLH-TSNLPSYTPTINMPNTSVVLDTDAEFVSDSSSS 662
            +     SS    ++ P T +  P L  T+  P+ T    +P++S  L T    +S +++ 
Sbjct: 3761 TTPTVTSSKATPFSSPGTATALPALRSTATTPTATSFTAIPSSS--LGTTWTRLSQTTTP 3818

Query: 663  SSSSSSSSSSGPPLPLPSVSQSHHLFSSILPSTRASVHLLKSTSDASTPWSSSPSPLPVS 722
            +++ S+++ S  P       ++ H  S++L +T  +    ++T   +TP S+  +     
Sbjct: 3819 TATMSTATPSSTP-------ETAHT-STVLTTTATTT---RATGSVATPSSTPGTAHTTK 3867

Query: 723  LTTSTSAPLSVSQTTLPQSSST-PVLPRARETPVTSFQTSTMTSFMTMLHSSQTADLKSQ 781
            + T+T+   +V+ ++ P ++ T PV      TP TS  T T +S     H          
Sbjct: 3868 VPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGSTVTPSSVPGTTH---------- 3917

Query: 782  STPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESSTEQTLPATSTN------L 835
             TP      T + +   ++ P+ ST+     S  PPSL  ++T  T   ++TN       
Sbjct: 3918 -TPTVLTTTTTTVATGSMATPSSSTQ----TSGTPPSLITTATTITATGSTTNPSSTPGT 3972

Query: 836  AQMSPTFTTTILKTSQPLMT-TPGTLSSTASLVTGPIAVQTTAGKQLSLTHPEIL--VPQ 892
              + P  TTT    +    T TP +   T      P    TT G+ LS + P  +     
Sbjct: 3973 TPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWT 4032

Query: 893  ISTEGGISTERNRVIVDATTGLIPLTSVPTSAKEMTTKLGVTAEYS--PASRSLGTSPSP 950
             +T G + T     I + +TG    TS   +A   TT+    A  S  P+SR+  + PSP
Sbjct: 4033 SATSGTLGTTH---ITEPSTG----TSHTPAATTGTTQHSTPALSSPHPSSRTTESPPSP 4085

Query: 951  QTT----------VVSTAEDLAPKSATFAVQSSTQSP-TTVSSSASVNSCA 990
             TT            +TA     +++T    S T +P TTV ++     CA
Sbjct: 4086 GTTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTTGCEPQCA 4136



 Score = 72.8 bits (177), Expect = 2e-12
 Identities = 143/651 (21%), Positives = 244/651 (37%), Gaps = 111/651 (17%)

Query: 273  TPSRKRNSSGPDLSWLHFYRTAASSPLLDLSSSSESTEKLNNSTG---LQSSSVSQTKTM 329
            T S    SS P  +W+   +T A++      S++  +     +     L S++ + T T 
Sbjct: 2980 TSSTATPSSTPGTTWILTEQTTAATTTATTGSTAIPSSTPGTAPPPKVLTSTATTPTATS 3039

Query: 330  HVATVFTDGGPRTLRSLTVSLGPVSKTEGFPKDSRIATTSSSVLLSPSAVESRRNSRVTG 389
              AT  +   PRT  +L V     +K+         AT+ + +             + T 
Sbjct: 3040 SKAT--SSSSPRTATTLPVLTSTATKST--------ATSFTPIPSFTLGTTGTLPEQTTT 3089

Query: 390  NPGDEEFIEPSTENEFGLTSLRWQNDSPTFGEHQLASSSEVQNGSPMSQTETVSRSVAPM 449
                   I PS+  E   TS      + T       S+     G+    TE  + +    
Sbjct: 3090 PMATMSTIHPSSTPETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWILTELTTAATTTA 3149

Query: 450  RGGEITAH-------WLLTNSTTSADVTGSSASYPEGVNASVLTQFSDSTVQSGGSHTAL 502
              G            W+LT  +T+A VT  + S          T  + ST  + G+   L
Sbjct: 3150 ATGPTATPSSTPGTTWILTEPSTTATVTVPTGS----------TATASSTRATAGTLKVL 3199

Query: 503  GDRSYSESSSTSSSESLNSSAPRGERSIAGISYGQVRGTAIEQR---TSSDHTDHTYLSS 559
               S + + +  SS +  SS+P    ++  +       TA       +SS  T  T LS 
Sbjct: 3200 --TSTATTPTVISSRATPSSSPGTATALPALRSTATTPTATSVTAIPSSSLGTAWTRLSQ 3257

Query: 560  TFTKGERALLSITDNSSSSDIVESSTSYIKISNSSHSEYSSFFHAQTERSNISSYDGEYA 619
            T T    A +S    SS+ + V +ST                    T  +  +   G  A
Sbjct: 3258 TTTP--TATMSTATPSSTPETVHTST------------------VLTTTTTTTRATGSVA 3297

Query: 620  QPSTESPVLHTSNLPSYTPT------INMPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSG 673
             PS+     HT+ +P+ T T       + P T++   T   ++S +++ ++  S+ +   
Sbjct: 3298 TPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTAL---TPPVWISTTTTPTTRGSTVT--- 3351

Query: 674  PPLPLPSVSQSHHLFSSILPSTRASVHLLKSTSDASTPWSSSP-SPLPVSLTTSTSAPLS 732
             P  +P  + +    +++L +T  +V    +T   +TP SS+  S  P SLTT+ +   +
Sbjct: 3352 -PSSIPGTTHT----ATVLTTTTTTV----ATGSMATPSSSTQTSGTPPSLTTTATTITA 3402

Query: 733  VSQTTLPQSSS-----TPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADLKSQ------ 781
               TT P S+       PVL     TP  +  T T +S +   H+    +  +       
Sbjct: 3403 TGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSL 3462

Query: 782  --STPHQEKVITESKSPSLV--------SLPTESTKAVTTN----------SPLPPSLTE 821
              S+PH  +    S +  ++        S  T  T A TT+          SP P S T 
Sbjct: 3463 PPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTPAATTSTTQHSTPALSSPHPSSRTT 3522

Query: 822  SSTEQ---TLPATSTNLAQMSPTFTTTILKTSQPLMTTPGTLSSTASLVTG 869
             S      T P  +   ++ + T T +  +TS  L ++P +   T  + TG
Sbjct: 3523 ESPPSPGTTTPGHTRGTSRTTATATPSKTRTSTLLPSSPTSAPITTVVTTG 3573



 Score = 72.4 bits (176), Expect = 3e-12
 Identities = 180/791 (22%), Positives = 290/791 (36%), Gaps = 143/791 (18%)

Query: 173  SGSSSRTNFTILPVGYSLEIATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTAS 232
            S    R   T  P    LE AT  T+Q    A  S   P+SS        A  T   T S
Sbjct: 1602 SDDHCRGRATTPPPTTELETATTTTTQ----ALFSTPQPTSSPGLTRAPPASTTAVPTLS 1657

Query: 233  EMGTERAMGLSEEWTVHSQEATTSAWSPS-FLPALEMGELTTPSRKRNSSGPDLSW---- 287
            E G       S   T  +   TT A S    +P +    L T S    ++G   +W    
Sbjct: 1658 E-GLTSPRYTSTLGTATTGGPTTPAGSTEPTVPGVATSTLPTRSALPGTTGSLGTWRPSQ 1716

Query: 288  ---LHFYRTAASSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLR 344
               L     A S      ++S+ S E L  S     +S   T     +T  T+     L 
Sbjct: 1717 PPTLAPTTMATSRARPTGTASTASKEPLTTSLAPTLTSELSTSQAETSTPRTETTMSPLT 1776

Query: 345  SLTVSLGPV------SKTEGFPKD--------------SRIATTSSSVLLSPSAVESRRN 384
            + T S G          TE F  D                I      +  +P ++E R  
Sbjct: 1777 NTTTSQGTTRCQPKCEWTEWFDVDFPTSGVAGGDMETFENIRAAGGKMCWAPKSIECRA- 1835

Query: 385  SRVTGNPGDEEFIEPSTENEFGL------TSLRWQNDSPTFGEHQLASSSEVQ-----NG 433
                     E + E S +    +      T L  +N+  T G   +  +  V+     + 
Sbjct: 1836 ---------ENYPEVSIDQVGQVLTCSLETGLTCKNEDQT-GRFNMCFNYNVRVLCCDDY 1885

Query: 434  SPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADVTGSSASYPEGVNASVLTQFSDSTV 493
            S    T   S +  P      T  W+LT  TT+A  T S+ S          T    ST+
Sbjct: 1886 SHCPSTPATSSTATPSSTPGTT--WILTKPTTTATTTASTGS----------TATPTSTL 1933

Query: 494  QSGGSHTALGDRSYSESSSTSSSESLNSSAPRGERSIAGISYGQVRGTAIEQR---TSSD 550
            ++      L   + + + + +SS++  SS+P    ++  +       TA       +SS 
Sbjct: 1934 RTAPPPKVL--TTTATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSVTPIPSSSL 1991

Query: 551  HTDHTYLSSTFTKGERALLSITDNSSSSDIVESSTSYIKISNSSHSEYSSFFHAQTERSN 610
             T  T LS T T    A +S    SS+ +   +ST                    T  + 
Sbjct: 1992 GTTWTRLSQTTTP--TATMSTATPSSTPETAHTST------------------VLTATAT 2031

Query: 611  ISSYDGEYAQPSTESPVLHTSNLPSYTPT------INMPNTSVVLDTDAEFVSDSSSSSS 664
             +   G  A PS+     HT+ +P+ T T       + P T++   T   ++S +++ ++
Sbjct: 2032 TTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTAL---TPPVWISTTTTPTT 2088

Query: 665  SSSSSSSSGPPLPLPSVSQSHHLFSSILPSTRASVHLLKSTSDASTPWSSSP-SPLPVSL 723
              S+ +    P  +P  + +    +++L +T  +V    +T   +TP SS+  S  P SL
Sbjct: 2089 RGSTVT----PSSIPGTTHT----ATVLTTTTTTV----ATGSMATPSSSTQTSGTPPSL 2136

Query: 724  TTSTSAPLSVSQTTLPQSSS-----TPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADL 778
            TT+ +   +   TT P S+       PVL     TP  +  T T +S +   H+    + 
Sbjct: 2137 TTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSNTVTPSSALGTTHTPPVPNT 2196

Query: 779  KS--------QSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESSTEQTLPA 830
             +         S+PH  +    S +  ++     +  +  T+  L  + T  +T+ + PA
Sbjct: 2197 MATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTL--AATTGTTQHSTPA 2254

Query: 831  TSTNLAQMSPTFTTTILKTSQPLMTTPGTLSSTASLVTGPIAVQTTAGKQLSLTHPEILV 890
                L+   P+  TT    S P  TTPG  ++T+         +TTA    S T    L+
Sbjct: 2255 ----LSSPHPSSRTTESPPS-PGTTTPGHTTATS---------RTTATATPSKTRTSTLL 2300

Query: 891  PQISTEGGIST 901
            P   T   I+T
Sbjct: 2301 PSSPTSAPITT 2311



 Score = 71.6 bits (174), Expect = 5e-12
 Identities = 112/431 (25%), Positives = 178/431 (41%), Gaps = 84/431 (19%)

Query: 621  PSTESPVLHTSNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPL-- 678
            PST  P   ++  PS TP      T     T A   + + S+++ +S+  ++ PP  L  
Sbjct: 1889 PST--PATSSTATPSSTPGTTWILTKPT--TTATTTASTGSTATPTSTLRTAPPPKVLTT 1944

Query: 679  ----PSVSQSHHLFSSILPSTRASVHLLKSTSDASTPWSSSPSPLPVSLTTSTSAPLSVS 734
                P+V+ S    SS  P T  ++  L+ST  A+TP ++S +P+P S   +T   LS  
Sbjct: 1945 TATTPTVTSSKATPSSS-PGTATALPALRST--ATTPTATSVTPIPSSSLGTTWTRLS-- 1999

Query: 735  QTTLPQSSSTPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADLKSQS--TPHQEKV--- 789
            QTT P ++ +   P +  TP T+  ++ +T+  T   ++ +    S +  T H  KV   
Sbjct: 2000 QTTTPTATMSTATPSS--TPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTT 2057

Query: 790  ------ITESKSPSLVSLP--------TESTKAVTTNSPLPPSLTESSTEQTL------- 828
                   T S SP     P        T +T+  T      P  T ++T  T        
Sbjct: 2058 TTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVAT 2117

Query: 829  -----PATSTNLAQMSPTFTTTIL------KTSQPLMTTPGT------LSSTASLVTGPI 871
                 P++ST  +   P+ TTT         T+ P  +TPGT      L++TA   T P 
Sbjct: 2118 GSMATPSSSTQTSGTPPSLTTTATTITATGSTTNP-SSTPGTTPIPPVLTTTA---TTPA 2173

Query: 872  AVQTTA--GKQLSLTHPEILVPQISTEGGISTERNR------VIVDATTGLIPLTSVP-- 921
            A   T      L  TH   +   ++T  G S   +           AT+G++  T +   
Sbjct: 2174 ATSNTVTPSSALGTTHTPPVPNTMATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEP 2233

Query: 922  --TSAKEMTTKLGVTAEYSPA-------SRSLGTSPSPQTTVVSTAEDLAPKSATFAVQS 972
               ++  +    G T   +PA       SR+  + PSP TT        +  +AT A  S
Sbjct: 2234 STVTSHTLAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTAT-ATPS 2292

Query: 973  STQSPTTVSSS 983
             T++ T + SS
Sbjct: 2293 KTRTSTLLPSS 2303



 Score = 67.4 bits (163), Expect = 9e-11
 Identities = 190/830 (22%), Positives = 294/830 (35%), Gaps = 153/830 (18%)

Query: 247  TVHSQEATTSAWSP---SFLPALEMGELTTPSRKRNSSGPDLS----WLHFYRTAASSPL 299
            TV S +AT S+ SP   + LPAL     TTP+    +  P  S    W    +T   +  
Sbjct: 1950 TVTSSKATPSS-SPGTATALPALR-STATTPTATSVTPIPSSSLGTTWTRLSQTTTPTAT 2007

Query: 300  LDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVSKTEGF 359
            +  ++ S + E  + ST L +++ +   T  VAT      P T  +  V   P + T GF
Sbjct: 2008 MSTATPSSTPETAHTSTVLTATATTTGATGSVAT--PSSTPGTAHTTKV---PTTTTTGF 2062

Query: 360  ---PKDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQNDS 416
               P  S     +  V +S +   + R S VT +        P T +    T L     +
Sbjct: 2063 TATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSS------IPGTTHT--ATVLTTTTTT 2114

Query: 417  PTFGEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADVTGSSASY 476
               G     SSS   +G+P S T T +   A             T STT+   T  +   
Sbjct: 2115 VATGSMATPSSSTQTSGTPPSLTTTATTITA-------------TGSTTNPSSTPGTTPI 2161

Query: 477  PEGVNASVLTQFSDSTVQSGGSHTALGDRSYSESSSTSSSESLNSSAPRGERSIAGISYG 536
            P  +  +  T  + S   +  S  ALG        +T +    N+ A    RS+   S  
Sbjct: 2162 PPVLTTTATTPAATSNTVTPSS--ALG--------TTHTPPVPNTMATTHGRSLPPSSPH 2211

Query: 537  QVRGTAIEQRTSSDHTDHTYLSSTFTKGERALLSITDNSSSSDIVESSTSYIKISNSSHS 596
             VR       +    T H    ST T    A        +++   + ST  +   + S  
Sbjct: 2212 TVRTAWTSATSGILGTTHITEPSTVTSHTLA--------ATTGTTQHSTPALSSPHPSSR 2263

Query: 597  EYSSFFHAQTERSNISSYDGEYAQPSTESPVLHTSNLPSYTPTINMPNTSVV-------- 648
               S     T     ++        +T S    ++ LPS +PT + P T+VV        
Sbjct: 2264 TTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLPS-SPT-SAPITTVVTMGCEPQC 2321

Query: 649  -----LDTDAEFVSDSSSSSSSSSSSSSSG-----------------PPLPLPSVSQ--S 684
                 LD        S     + S+  ++G                 P +PL  + Q   
Sbjct: 2322 AWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQVVE 2381

Query: 685  HHLFSSILPSTRASVHLLKSTSD-------------ASTPWSSS---PSPLP------VS 722
              L   ++   R  V   K   +              STP +SS   PS  P        
Sbjct: 2382 CSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAMPSSTPGTTWILTE 2441

Query: 723  LTTSTSAPLSVSQTTLPQSSSTPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADLKSQS 782
            LTT+ +   S   T  P  SSTP        P T+   +  T       S+Q     +  
Sbjct: 2442 LTTTATTTESTGSTATP--SSTPGTTWILTEPSTTATVTVPTGSTATASSTQA----TAG 2495

Query: 783  TPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLT--ESSTEQTLPATS--TNLAQM 838
            TPH     T     S  + P  S    T    L  + T   +++   +P++S  T   ++
Sbjct: 2496 TPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRL 2555

Query: 839  SPTFTTTILKTSQPLMTTPGTLSSTASLVTGPIAVQTTAGKQLSLTHPEILVPQISTEGG 898
            S T T T   ++    +TP T+ ++  L T      TT G   S+  P       ST G 
Sbjct: 2556 SQTTTPTATMSTATPSSTPETVHTSTVLTT----TATTTGATGSVATPS------STPGT 2605

Query: 899  ISTERNRVIVDATTGLIPLTSVPTSA--KEMTTKLGVTAEYSPASRSLGTSPS------- 949
              T   +V+   TTG    T+ P+S+     T  + ++   +P +R    +PS       
Sbjct: 2606 AHT--TKVLTTTTTG---FTATPSSSPGTARTLPVWISTTTTPTTRGSTVTPSSIPGTTH 2660

Query: 950  ------PQTTVVSTAEDLAPKSATFAVQSSTQSPTTVSSSASVNSCAVNP 993
                    TT V+T     P S+T     +  S TT +++ +      NP
Sbjct: 2661 TPTVLTTTTTTVATGSMATPSSST-QTSGTPPSLTTTATTITATGSTTNP 2709



 Score = 64.3 bits (155), Expect = 8e-10
 Identities = 206/941 (21%), Positives = 338/941 (35%), Gaps = 154/941 (16%)

Query: 146  TSGKSHAASDAPENLTLLAETADARGRSGSSSRTNFTILPVGYSLEIATALTSQSGN-LA 204
            TS K+ ++S      TL   T+ A      S+ T+FT +P  ++L     L  Q+   +A
Sbjct: 3038 TSSKATSSSSPRTATTLPVLTSTAT----KSTATSFTPIP-SFTLGTTGTLPEQTTTPMA 3092

Query: 205  SESLHLPSSSSEFDERIAAFQTKSGTA---SEMGTERAMGLSEEWTVH---SQEATTSAW 258
            + S   PSS+ E         TK+ T    S M T  +      W +    +   TT+A 
Sbjct: 3093 TMSTIHPSSTPETTHTSTVLTTKATTTRATSSMSTPSSTP-GTTWILTELTTAATTTAAT 3151

Query: 259  SPSFLPALEMGE---LTTPSRKRNSSGPDLSWLHFYRTAASSPLLDLSSSSESTEKLNNS 315
             P+  P+   G    LT PS     + P  S      T A++  L + +S+ +T  + +S
Sbjct: 3152 GPTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRATAGTLKVLTSTATTPTVISS 3211

Query: 316  TGLQSSS---------VSQTKTMHVATVFTDGGPRTLRSLTVSLGPVSKTEGFPKDSRIA 366
                SSS         +  T T   AT  T     +L +    L   +        +  +
Sbjct: 3212 RATPSSSPGTATALPALRSTATTPTATSVTAIPSSSLGTAWTRLSQTTTPTATMSTATPS 3271

Query: 367  TTSSSVLLSPSAVESRRNSRVTGN-------PGDEEFIEPSTENEFGLTSLRWQNDSPTF 419
            +T  +V  S     +   +R TG+       PG     +  T    G T+    +     
Sbjct: 3272 STPETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTAL 3331

Query: 420  GEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADVTGSSASYPEG 479
                  S++     +P ++  TV+ S  P  G   TA  L T +TT A  TGS A+    
Sbjct: 3332 TPPVWISTTT----TPTTRGSTVTPSSIP--GTTHTATVLTTTTTTVA--TGSMAT---- 3379

Query: 480  VNASVLTQFSDSTVQSGGSHTALGDRSYSESSSTSSSESLNSSAPRGERSIAGISYGQVR 539
                       S+ Q+ G+  +L   + + ++ T++  + N S+  G   I  +      
Sbjct: 3380 ---------PSSSTQTSGTPPSL---TTTATTITATGSTTNPSSTPGTTPIPPVLTTTAT 3427

Query: 540  GTAIEQRTSSDHTDHTYLSSTFTKGERALLSITDNSSSSDIVESSTSYIKISNSSHSEYS 599
              A    TSS  T  + L +T T     + + T  +    +  SS   ++ + +S +   
Sbjct: 3428 TPAA---TSSTVTPSSALGTTHTP---PVPNTTATTHGRSLPPSSPHTVRTAWTSATSGI 3481

Query: 600  SFFHAQTERSNISSYDGEYAQPSTESPVLHTSNLPSYTPTINMPNTSVVLDTDAEFVSDS 659
                  TE S ++S+          +P   TS     TP ++ P+ S             
Sbjct: 3482 LGTTHITEPSTVTSH----------TPAATTSTTQHSTPALSSPHPS------------- 3518

Query: 660  SSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSILPSTRASVHLLKSTSDASTPWSSSPSPL 719
                    S ++  PP P  + +  H   +S     R +     S +  ST   SSP+  
Sbjct: 3519 --------SRTTESPPSP-GTTTPGHTRGTS-----RTTATATPSKTRTSTLLPSSPTSA 3564

Query: 720  PVSLTTSTSAPLSVSQTTLPQSSSTPVLPRARETPVTS---FQTSTMTSFMTMLHSSQTA 776
            P++   +T           PQ + +  L  +   P  S   F T +           Q  
Sbjct: 3565 PITTVVTTGCE--------PQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPL 3616

Query: 777  DLKSQS-----TPHQE--KVITESKSPSLVSLPTESTKAVTT--------------NSPL 815
             L+ ++      P +E  +V+  S    LV    E                     + P 
Sbjct: 3617 GLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPS 3676

Query: 816  PPSLTESSTEQTLPATSTNLAQMSPTFTTT--ILKTSQPLMTTPGTLSSTASLVTGPIAV 873
             P+ + ++T  + P T+  L +++ T TTT     T+ P  T   T   T    T  + V
Sbjct: 3677 TPATSSTATPSSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTTWILTEPSTTATVTV 3736

Query: 874  QTTAGKQLSLTHPEILVPQISTEGGISTERNRVIVDATTGLIP--LTSVPTSAKEMTTKL 931
             T +    S T      P +ST     T  +     AT    P   T++P      TT  
Sbjct: 3737 PTGSTATASSTQATAGTPHVSTTATTPTVTSS---KATPFSSPGTATALPALRSTATTPT 3793

Query: 932  GVTAEYSPASRSLGTS---PSPQTTVVSTAEDLAPKSATFAVQSSTQSPTTVSSSASVNS 988
              +    P+S SLGT+    S  TT  +T     P S      +ST   TT +++ +  S
Sbjct: 3794 ATSFTAIPSS-SLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTTATTTRATGS 3852

Query: 989  CAV---NPCLHNGECVADNTSRGY---------HCRCPPSW 1017
             A     P   +   V   T+ G+           R PP W
Sbjct: 3853 VATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVW 3893



 Score = 63.9 bits (154), Expect = 1e-09
 Identities = 86/348 (24%), Positives = 126/348 (36%), Gaps = 35/348 (10%)

Query: 658  DSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSILPSTRASVHLLKSTSDASTPWSS-SP 716
            D  S   S+ ++SS+  P   P  +        IL     +     ST   +TP S+   
Sbjct: 1883 DDYSHCPSTPATSSTATPSSTPGTTW-------ILTKPTTTATTTASTGSTATPTSTLRT 1935

Query: 717  SPLPVSLTTSTSAPLSVSQTTLPQSS--STPVLPRARETPVTSFQTSTMTSFMTMLHSSQ 774
            +P P  LTT+ + P   S    P SS  +   LP  R T  T   TS      + L ++ 
Sbjct: 1936 APPPKVLTTTATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSVTPIPSSSLGTTW 1995

Query: 775  TADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESSTEQTLPATSTN 834
            T   ++ +        T S +P      T  T   TT        T SST  T   T   
Sbjct: 1996 TRLSQTTTPTATMSTATPSSTPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKV- 2054

Query: 835  LAQMSPTFTTTILKTSQPLMTTPGTLSSTASLVTGPIAVQTTAGKQLSLTHPEILVPQIS 894
                 PT TTT          TP +   TA      I+  TT   + S   P  +     
Sbjct: 2055 -----PTTTTT------GFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTH 2103

Query: 895  TEGGISTERNRVIVD--ATTGLIPLTS-VPTSAKEMTTKLGVTAEYSPASRSLGTSPSP- 950
            T   ++T    V     AT      TS  P S     T +  T   +  S + GT+P P 
Sbjct: 2104 TATVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPP 2163

Query: 951  -----QTTVVSTAEDLAPKSATFAVQSSTQSPTTVSSSASVNSCAVNP 993
                  TT  +T+  + P SA      +T +P   ++ A+ +  ++ P
Sbjct: 2164 VLTTTATTPAATSNTVTPSSAL----GTTHTPPVPNTMATTHGRSLPP 2207



 Score = 36.6 bits (83), Expect = 0.17
 Identities = 54/190 (28%), Positives = 74/190 (38%), Gaps = 40/190 (21%)

Query: 827  TLPATSTNLAQMSPTFTTTILKTSQPLMTTPG-------------TLSS--TASLVTGPI 871
            T P  +T L   + T T  +  T QP  ++PG             TLS   T+   T  +
Sbjct: 1611 TTPPPTTELETATTTTTQALFSTPQP-TSSPGLTRAPPASTTAVPTLSEGLTSPRYTSTL 1669

Query: 872  AVQTTAGKQLSLTHPEILVPQISTEGGISTERNRVIVDATTGLI-------PLTSVPTSA 924
               TT G        E  VP ++T    ST   R  +  TTG +       P T  PT+ 
Sbjct: 1670 GTATTGGPTTPAGSTEPTVPGVAT----STLPTRSALPGTTGSLGTWRPSQPPTLAPTTM 1725

Query: 925  KEMTTKLGVTAEYSPASRS-LGTSPSPQTT---VVSTAEDLAPKSATFAVQSSTQSP-TT 979
               T++   T   S AS+  L TS +P  T     S AE   P++ T      T SP T 
Sbjct: 1726 --ATSRARPTGTASTASKEPLTTSLAPTLTSELSTSQAETSTPRTET------TMSPLTN 1777

Query: 980  VSSSASVNSC 989
             ++S     C
Sbjct: 1778 TTTSQGTTRC 1787


>gi|161019170 mucin 5AC [Homo sapiens]
          Length = 6207

 Score =  105 bits (262), Expect = 3e-22
 Identities = 241/1036 (23%), Positives = 390/1036 (37%), Gaps = 125/1036 (12%)

Query: 21   LLLPPAAPGTRDPPPSPARRALSLAPLAGAGLELQLERRPEREPPPTPPRERRGPATPGP 80
            +L  P+   T   P      A S    AG          P        P    G AT  P
Sbjct: 3102 ILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALP 3161

Query: 81   SYRAPEPGAATQRGPSGRAPRGGSADAAWKHWPESNTE-AHVENITFYQNQEDF--STVS 137
            + R+    A T    S  A    S    W    ++ T  A +   T     E    STV 
Sbjct: 3162 ALRST---ATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVL 3218

Query: 138  SKEGVMVQTSGKSHAASDAP---ENLTLLAETADARGRSGSSSRTNFTILPVGYSLEIA- 193
            +        +G     S  P       +L  T      + SSS      LPV  S     
Sbjct: 3219 TTTATTTGATGSVATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGTARTLPVWISTTTTP 3278

Query: 194  -------------------TALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTASEM 234
                               T LT+ +  +A+ S+  PSSS++           + TA+  
Sbjct: 3279 TTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTTHTPPVPNTTATTH 3338

Query: 235  GTERAMGLSEEWTVHSQ--EATTSAWSPSFLPALEMGELTTPSRKRNS---SGPDLSWLH 289
            G  R++  S   TV +    AT+     + +     G   TP+    +   S P LS  H
Sbjct: 3339 G--RSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPH 3396

Query: 290  FYRTAASSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTM--------HVATVFTDG-GP 340
                   SP    +++   T   + +T   + S ++T T+         + TV T G  P
Sbjct: 3397 PSSRTTESPPSPGTTTPGHTRATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTMGCEP 3456

Query: 341  RTLRSLTVSLG-PVSKTEG--FPKDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFI 397
            +   S  +    P+    G  F   S I     +V   P  +E R  ++  G P  E   
Sbjct: 3457 QCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQ-PGVPLRELGQ 3515

Query: 398  EPSTENEFGLTSLRWQNDSPTFGEHQLASSSEVQ----NGSPMSQTETVSRSVAPMRGGE 453
                  +FGL       +    G+ ++  + E++    N      T   S +  P     
Sbjct: 3516 VVECSLDFGLVC----RNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTATPSSTPG 3571

Query: 454  ITAHWLLTNSTTSADVTGSSASYPEGVNASVLTQFSDSTVQSGGSHTALGDRSYSESSST 513
             T  W+LT  TT+A  T ++ S          T    ST  +      L   S + + + 
Sbjct: 3572 TT--WILTEQTTAATTTATTGS----------TAIPSSTPGTAPPPKVL--TSTATTPTA 3617

Query: 514  SSSESLNSSAPRGERSIAGISYGQVRGTAIEQRTSSDHTDHTYLSSTFTKGERALLSITD 573
            +SS++ +SS+PR   ++  ++    + TA    TS        L +T T  E+   + T 
Sbjct: 3618 TSSKATSSSSPRTATTLPVLTSTATKSTA----TSFTPIPSFTLGTTGTLPEQ---TTTP 3670

Query: 574  NSSSSDIVESSTSYIKISNSSHSEYSSFFHAQTERSNISSYDGE--YAQPSTESPVLHTS 631
             ++ S I  SST     +++  +  ++   A +  S  SS  G        T +     +
Sbjct: 3671 MATMSTIHPSSTPETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWILTELTTAATTTAA 3730

Query: 632  NLPSYTPTINMPNTSVVL---DTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLF 688
              P+ TP+ + P T+ +L    T A     + S++++SS+ +++G    L S + +  + 
Sbjct: 3731 TGPTATPS-STPGTTWILTEPSTTATVTVPTGSTATASSTRATAGTLKVLTSTATTPTVI 3789

Query: 689  SSIL-----PSTRASVHLLKSTSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQSSS 743
            SS       P T  ++  L+ST  A+TP ++S + +P S  +  +A   +SQTT P ++ 
Sbjct: 3790 SSRATPSSSPGTATALPALRST--ATTPTATSVTAIPSS--SLGTAWTRLSQTTTPTATM 3845

Query: 744  TPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADLKSQSTPHQEKV---------ITESK 794
            +   P +    V +    T T+  T    S      +  T H  KV          T S 
Sbjct: 3846 STATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSS 3905

Query: 795  SPSLVSLPTESTKAVTTNSPLPPSLTESSTEQTLPATSTNLAQMSPTFTTTILKTSQPLM 854
            SP     P       TT +    ++T SS    +P T T+ A +  T TTT+   S   M
Sbjct: 3906 SPGTALTPPVWISTTTTPTTRGSTVTPSS----IPGT-THTATVLTTTTTTVATGS---M 3957

Query: 855  TTPGTLSSTASLVTGPIAVQTTA---GKQLSLTHPEILVPQ--ISTEGGISTERNRVIVD 909
             TP + + T+     P    TTA   G+ L  + P  +      +T G + T     I +
Sbjct: 3958 ATPSSSTQTSGTTHTPPVPNTTATTHGRSLPPSSPHTVRTAWTSATSGILGTTH---ITE 4014

Query: 910  ATTGLIPLTSVPTSAKEMTTKLGVTAEYSP--ASRSLGTSPSPQTTVVSTAEDLAPKSAT 967
             +T    +TS   +A   TT+    A  SP  +SR+  + PSP TT        +  +AT
Sbjct: 4015 PST----VTSHTPAATTSTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRGTSRTTAT 4070

Query: 968  FAVQSSTQSPTTVSSS 983
             A  S T++ T + SS
Sbjct: 4071 -ATPSKTRTSTLLPSS 4085



 Score =  101 bits (251), Expect = 6e-21
 Identities = 213/923 (23%), Positives = 353/923 (38%), Gaps = 134/923 (14%)

Query: 194  TALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTASEMGTERAMGLSEEWTVHSQ-- 251
            T LT+ +  +A+ S+  PSSS++           + TA+  G  R++  S   TV +   
Sbjct: 4445 TVLTTTTTTVATGSMATPSSSTQTSGTTHTPPVPNTTATTHG--RSLSPSSPHTVRTAWT 4502

Query: 252  EATTSAWSPSFLPALEMGELTTPSRKRNS---SGPDLSWLHFYRTAASSPLLDLSSSSES 308
             AT+     + +     G   TP+    +   S P LS  H       SP    +++   
Sbjct: 4503 SATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGH 4562

Query: 309  TEKLNNSTGLQSSSVSQTKTM--------HVATVFTDG-GPRTLRSLTVSLG-PVSKTEG 358
            T   + +T   + S ++T T+         + TV T G  P+   S  +    P+    G
Sbjct: 4563 TTATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSG 4622

Query: 359  --FPKDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQNDS 416
              F   S I     +V   P  +E R  ++  G P  E         +FGL       + 
Sbjct: 4623 GDFDTYSNIRAAGGAVCEQPLGLECRAQAQ-PGVPLGELGQVVECSLDFGLVC----RNR 4677

Query: 417  PTFGEHQLASSSEVQ----NGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADVTGS 472
               G+ ++  + E++    N      T   S +  P      T  W+LT  TT+A  T S
Sbjct: 4678 EQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAMPSSTPGTT--WILTELTTTATTTAS 4735

Query: 473  SASYPEGVNASVLTQFSDSTVQSGGSHTALGDRSYSESSSTSSSESLNSSAPRGERSIAG 532
            + S          T    ST  +      L   S + + + +SS++ +SS+PR   ++  
Sbjct: 4736 TGS----------TATPSSTPGTAPPPKVL--TSPATTPTATSSKATSSSSPRTATTLPV 4783

Query: 533  ISYGQVRGTAIEQRTSSDHTDHTYLSSTFTKGER-----ALLSITDNSSSSDIVESSTSY 587
            ++    + TA    TS      + L +T T  E+     A +S    SS+ +   +ST  
Sbjct: 4784 LTSTATKSTA----TSVTPIPSSTLGTTGTLPEQTTTPVATMSTIHPSSTPETTHTSTVL 4839

Query: 588  IKISNSSHSEYSSFFHAQTE-----------RSNISSYDGEYAQPSTE-----------S 625
               + ++ +  S+   + T             +  ++  G  A PS+            +
Sbjct: 4840 TTKATTTRATSSTSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTELTT 4899

Query: 626  PVLHTSNLPSYTPTINMPNTSVVL---DTDAEFVSDSSSSSSSSSSSSSSGPP-----LP 677
                T++  S     + P T+ +L    T A     + S++++SS+ +++G P       
Sbjct: 4900 TATTTASTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTAT 4959

Query: 678  LPSVSQSHHLFSSILPSTRASVHLLKSTSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTT 737
             P+V+ S    SS  P T  ++  L+ST  A+TP ++S + +P S   +T   LS  QTT
Sbjct: 4960 TPTVTSSKATPSSS-PGTATALPALRST--ATTPTATSFTAIPSSSLGTTWTRLS--QTT 5014

Query: 738  LPQSSSTPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADLKSQSTPHQEKV-------- 789
             P ++ +   P +    V +    T T+  T    S      +  T H  KV        
Sbjct: 5015 TPTATMSTATPSSTPETVHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGF 5074

Query: 790  -ITESKSPSLVSLPTESTKAVTTNS---PLPPSLTESSTEQTLPATSTNLAQMSPTFTTT 845
              T S SP     P  +T   T ++      P  T +ST  T  AT T     + T ++T
Sbjct: 5075 TATPSSSPGTALTPPTTTPMSTMSTIHTSSTPETTHTSTVLTTTATMTRATNSTATPSST 5134

Query: 846  ILKTS--QPLMTTPGTLSSTASLVTGPIAVQTTAGKQLSLTHPEILVPQISTEGGISTER 903
            +  T     L TT  T ++T S  T    + +T G    LT P  +   +   G  +T  
Sbjct: 5135 LGTTRILTELTTTATTTAATGSTAT----LSSTPGTTWILTEPSTIATVMVPTGSTAT-- 5188

Query: 904  NRVIVDATTGLIPLTSVPTSAKEMTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAEDLAP 963
                  +T G      V T+   M T    TA   P+S ++GT+ +P     S      P
Sbjct: 5189 ----ASSTLGTAHTPKVVTTMATMPT---ATASTVPSSSTVGTTRTPAVLPSS-----LP 5236

Query: 964  KSATFAVQSS---TQSPTTVSSSASVNSC---AVNPCLHNGECVADNTSRG---YHCRCP 1014
              +   V SS   T  PT   SS     C   A       GE + + T R    ++  C 
Sbjct: 5237 TFSVSTVSSSVLTTLRPTGFPSSHFSTPCFCRAFGQFFSPGEVIYNKTDRAGCHFYAVC- 5295

Query: 1015 PSWQGDDCSVD--VNECLSNPCP 1035
                   C +D     C ++P P
Sbjct: 5296 ----NQHCDIDRFQGACPTSPPP 5314



 Score = 99.8 bits (247), Expect = 2e-20
 Identities = 242/1059 (22%), Positives = 393/1059 (37%), Gaps = 137/1059 (12%)

Query: 23   LPPAAPGTRDPPPSPARRALSLAPLAGAGLELQLERRPEREP--PPTPPRERRGPATPGP 80
            +P + PGT  PP      A +    +         R     P    T  +      TP P
Sbjct: 3594 IPSSTPGTAPPPKVLTSTATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIP 3653

Query: 81   SYRAPEPGAATQRGPSGRAPRGGSADAAWKHWPESNTEAHVENITFYQNQEDFSTVSSKE 140
            S+     G   ++  +  A       ++      ++T    +  T  +     ST SS  
Sbjct: 3654 SFTLGTTGTLPEQTTTPMATMSTIHPSSTPETTHTSTVLTTKATTT-RATSSMSTPSSTP 3712

Query: 141  GVM------------VQTSGKSHAASDAPENLTLLAE---TADARGRSGSSSRTNFTILP 185
            G                 +G +   S  P    +L E   TA     +GS++  + T   
Sbjct: 3713 GTTWILTELTTAATTTAATGPTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRAT 3772

Query: 186  VGYSLEIATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGT--ASEMGTERAMGLS 243
             G +L++ T+  +    ++S +   PSSS      + A ++ + T  A+ +    +  L 
Sbjct: 3773 AG-TLKVLTSTATTPTVISSRAT--PSSSPGTATALPALRSTATTPTATSVTAIPSSSLG 3829

Query: 244  EEWTVHSQE----ATTSAWSPSFLPAL---------------EMGELTTPSRKRNSSG-- 282
              WT  SQ     AT S  +PS  P                   G + TPS    ++   
Sbjct: 3830 TAWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTT 3889

Query: 283  --PDLSWLHFYRTAASSPLLDLSS----SSESTEKLNNSTGLQSSSVSQTKTMHVATVFT 336
              P  +   F  T +SSP   L+     S+ +T     ST   SS    T T  V T  T
Sbjct: 3890 KVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTT 3949

Query: 337  D----GGPRTLRSLTVSLGPVSKTEGFPKDSRIATTSSSVL--LSPSAVESRRNSRVTGN 390
                 G   T  S T + G    T   P  +  ATT    L   SP  V +   S  +G 
Sbjct: 3950 TTVATGSMATPSSSTQTSGT---THTPPVPNTTATTHGRSLPPSSPHTVRTAWTSATSGI 4006

Query: 391  PGDEEFIEPSTENEF--GLTSLRWQNDSPTFGEHQLASSSEVQNGSPMS----QTETVSR 444
             G     EPST        T+   Q+ +P       +S +     SP +     T   SR
Sbjct: 4007 LGTTHITEPSTVTSHTPAATTSTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRGTSR 4066

Query: 445  SVAPMRGGEITAHWLLTNSTTSADVTG--SSASYPEGVNASVLTQFSDSTVQSGGSHTAL 502
            + A     +     LL +S TSA +T   ++   P+   +  L         SGG     
Sbjct: 4067 TTATATPSKTRTSTLLPSSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTY 4126

Query: 503  GDRSYSESSSTSSSESLNSSAPRGERSIAGISYGQVRGTAIEQRTSSDHTDHTYLSSTFT 562
             +   +  +       L   A + +  +     GQV   +++      + +         
Sbjct: 4127 SNIRAAGGAVCEQPLGLECRA-QAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCF 4185

Query: 563  KGERALLSITDNSSSSDIVESSTSYIKISNSSHSEYSSFFHAQTERSNISSYDGEYAQPS 622
              E  +         S    SST+    + SS    +      T  +  +   G  A PS
Sbjct: 4186 NYEIRVFCCNYGHCPSTPATSSTA----TPSSTPGTTWILTKLTTTATTTESTGSTATPS 4241

Query: 623  TESPVLHTSNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPP-----LP 677
            +          PS T T+ +P               + S++++SS+ +++G P       
Sbjct: 4242 STPGTTWILTEPSTTATVTVP---------------TGSTATASSTQATAGTPHVSTTAT 4286

Query: 678  LPSVSQSHHL-FSSILPSTRASVHLLKSTSDASTPWSSSPSPLPVSLTTSTSAPLSVSQT 736
             P+V+ S    FSS  P T  ++  L+ST  A+TP ++S + +P S   +T   LS  QT
Sbjct: 4287 TPTVTSSKATPFSS--PGTATALPALRST--ATTPTATSFTAIPSSSLGTTWTRLS--QT 4340

Query: 737  TLPQSSSTPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADLKSQS--TPHQEKVITESK 794
            T P ++ +   P +  TP T+  ++ +T+  T   ++ +    S +  T H  KV T + 
Sbjct: 4341 TTPTATMSTATPSS--TPETAHTSTVLTTTATTTRATGSVATPSSTPGTAHTTKVPTTTT 4398

Query: 795  SPSLVSLPTESTKAVTTNSPLPPSLTESSTEQTLPATSTNLAQMSPTFTTTILKTSQPL- 853
            +   V   T S+   T  +P P  ++ ++T  T  +T T  +    T T T+L T+    
Sbjct: 4399 TGFTV---TPSSSPGTARTP-PVWISTTTTPTTSGSTVTPSSVPGTTHTPTVLTTTTTTV 4454

Query: 854  ----MTTPGTLSSTASLVTGPIAVQTTA---GKQLSLTHPEILVPQ--ISTEGGISTERN 904
                M TP + + T+     P    TTA   G+ LS + P  +      +T G + T   
Sbjct: 4455 ATGSMATPSSSTQTSGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTH- 4513

Query: 905  RVIVDATTGLIPLTSVPTSAKEMTTKLGVTAEYSP--ASRSLGTSPSPQTT--------- 953
              I + +TG    TS   +A   TT+    A  SP  +SR+  + PSP TT         
Sbjct: 4514 --ITEPSTG----TSHTPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATS 4567

Query: 954  -VVSTAEDLAPKSATFAVQSSTQSP-TTVSSSASVNSCA 990
               +TA     +++T    S T +P TTV ++     CA
Sbjct: 4568 RTTATATPSKTRTSTLLPSSPTSAPITTVVTTGCEPQCA 4606



 Score = 96.7 bits (239), Expect = 1e-19
 Identities = 211/885 (23%), Positives = 332/885 (37%), Gaps = 105/885 (11%)

Query: 160  LTLLAETADARGRSGSSSRTNFTILPVGYSLEIATALTSQSGNLASESLHLPSSSSEFDE 219
            LT    TA     +GS++    T+        + T  T+ +    + S   PSSS     
Sbjct: 2600 LTKPTTTATTTASTGSTATPTSTLRTAPPPKVLTTTATTPT---VTSSKATPSSSPGTAT 2656

Query: 220  RIAAFQTKSGT--ASEMGTERAMGLSEEWTVHSQE----ATTSAWSPSFLPALE------ 267
             + A ++ + T  A+ +    +  L   WT  SQ     AT S  +PS  P         
Sbjct: 2657 ALPALRSTATTPTATSVTPIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVL 2716

Query: 268  ---------MGELTTPSRKRNSSG----PDLSWLHFYRTAASSPLLDLSS----SSESTE 310
                      G + TPS    ++     P  +   F  T +SSP   L+     S+ +T 
Sbjct: 2717 TATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTP 2776

Query: 311  KLNNSTGLQSSSVSQTKTMHVATVFTD----GGPRTLRSLTVSLGPVSKTEGFPKDSRIA 366
                ST   SS    T T  V T  T     G   T  S T + G    T   P  + +A
Sbjct: 2777 TTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGT---THTPPVPNTMA 2833

Query: 367  TTSSSVL--LSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGL--TSLRWQNDSPTFGEH 422
            TT    L   SP  V +   S  +G  G     EPST     L  T+   Q+ +P     
Sbjct: 2834 TTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTLAATTGTTQHSTPALSSP 2893

Query: 423  QLASSSEVQNGSPMS----QTETVSRSVAPMRGGEITAHWLLTNSTTSADVTG--SSASY 476
              +S +     SP +     T   SR+ A     +     LL +S TSA +T   +    
Sbjct: 2894 HPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTMGCE 2953

Query: 477  PEGVNASVLTQFSDSTVQSGGSHTALGDRSYSESSSTSSSESLNSSAPRGERSIAGISYG 536
            P+   +  L         SGG      +   +  +       L   A + +  +     G
Sbjct: 2954 PQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRA-QAQPGVPLRELG 3012

Query: 537  QVRGTAIEQRTSSDHTDHTYLSSTFTKGERALLSITDNSSSSDIVESSTSYIKISNSSHS 596
            QV   +++      + +           E  +         S    SST+      SS  
Sbjct: 3013 QVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAM----PSSTP 3068

Query: 597  EYSSFFHAQTERSNISSYDGEYAQPSTESPVLHTSNLPSYTPTINMPNTSVVLDTDAEFV 656
              +      T  +  +   G  A PS+          PS T T+ +P             
Sbjct: 3069 GTTWILTELTTTATTTESTGSTATPSSTPGTTWILTEPSTTATVTVP------------- 3115

Query: 657  SDSSSSSSSSSSSSSSGPP-----LPLPSVSQSHHL-FSSILPSTRASVHLLKSTSDAST 710
              + S++++SS+ +++G P        P+V+ S    FSS  P T  ++  L+ST  A+T
Sbjct: 3116 --TGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSS--PGTATALPALRST--ATT 3169

Query: 711  PWSSSPSPLPVSLTTSTSAPLSVSQTTLPQSSSTPVLPRARETPVTSFQTSTMTSFMTML 770
            P ++S + +P S   +T   LS  QTT P ++ +   P +    V +    T T+  T  
Sbjct: 3170 PTATSFTAIPSSSLGTTWTRLS--QTTTPTATMSTATPSSTPETVHTSTVLTTTATTTGA 3227

Query: 771  HSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESSTEQTLPA 830
              S      +  T H  KV+T + +    + P+ S     T   LP  ++ ++T  T  +
Sbjct: 3228 TGSVATPSSTPGTAHTTKVLTTTTT-GFTATPSSSPGTART---LPVWISTTTTPTTRGS 3283

Query: 831  TSTNLAQMSPTFTTTILKTSQPL-----MTTPGTLSSTASLVTGPIAVQTTA---GKQLS 882
            T T  +    T T T+L T+        M TP + + T+     P    TTA   G+ LS
Sbjct: 3284 TVTPSSIPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTTHTPPVPNTTATTHGRSLS 3343

Query: 883  LTHPEILVPQ--ISTEGGISTERNRVIVDATTGLIPLTSVPTSAKEMTTKLGVTAEYSP- 939
             + P  +      +T G + T     I + +TG    TS   +A   TT+    A  SP 
Sbjct: 3344 PSSPHTVRTAWTSATSGTLGTTH---ITEPSTG----TSHTPAATTGTTQHSTPALSSPH 3396

Query: 940  -ASRSLGTSPSPQTTVVSTAEDLAPKSATFAVQSSTQSPTTVSSS 983
             +SR+  + PSP TT        +  +AT A  S T++ T + SS
Sbjct: 3397 PSSRTTESPPSPGTTTPGHTRATSRTTAT-ATPSKTRTSTLLPSS 3440



 Score = 80.9 bits (198), Expect = 8e-15
 Identities = 103/379 (27%), Positives = 152/379 (40%), Gaps = 65/379 (17%)

Query: 621  PSTESPVLHTSNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPS 680
            PST  P   ++  PS TP      T     T A   + + S++  SS+  ++ PP  L S
Sbjct: 3555 PST--PATSSTATPSSTPGTTWILTEQT--TAATTTATTGSTAIPSSTPGTAPPPKVLTS 3610

Query: 681  VSQ-----SHHLFSSILPSTRASVHLLKSTSDASTPWSSSPSPLPVSLTTSTSAPLSVSQ 735
             +      S    SS  P T  ++ +L ST+  ST  S +P P   S T  T+  L   Q
Sbjct: 3611 TATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIP---SFTLGTTGTLP-EQ 3666

Query: 736  TTLPQSSSTPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKS 795
            TT P ++ + + P +  TP T+  ++ +T+  T   ++      S STP        S +
Sbjct: 3667 TTTPMATMSTIHPSS--TPETTHTSTVLTTKATTTRATS-----SMSTP--------SST 3711

Query: 796  PSLVSLPTESTKAVTTNSPLPPSLTESSTEQTLPATSTNLAQMSPTFTTTI----LKTSQ 851
            P    + TE T A TT +   P+ T SST    P T+  L + S T T T+      T+ 
Sbjct: 3712 PGTTWILTELTTAATTTAATGPTATPSST----PGTTWILTEPSTTATVTVPTGSTATAS 3767

Query: 852  PLMTTPGTLSSTASLVTGPIAVQTTAGKQLSLTHPEILVPQISTEGGISTERNRVIVDAT 911
                T GTL    S  T P  + + A                S+  G +T    +   AT
Sbjct: 3768 STRATAGTLKVLTSTATTPTVISSRATP--------------SSSPGTATALPALRSTAT 3813

Query: 912  TGLIPLTSVPTSAKEMTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSATFAVQ 971
            T                T   VTA  S +  +  T  S  TT  +T     P S    V 
Sbjct: 3814 T---------------PTATSVTAIPSSSLGTAWTRLSQTTTPTATMSTATPSSTPETVH 3858

Query: 972  SSTQSPTTVSSSASVNSCA 990
            +ST   TT +++ +  S A
Sbjct: 3859 TSTVLTTTTTTTRATGSVA 3877



 Score = 76.6 bits (187), Expect = 1e-13
 Identities = 106/384 (27%), Positives = 169/384 (44%), Gaps = 45/384 (11%)

Query: 621  PSTESPVLHTSNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPL-- 678
            PST  P   ++  PS TP      T     T A   + + S+++ +S+  ++ PP  L  
Sbjct: 2579 PST--PATSSTATPSSTPGTTWILTKPT--TTATTTASTGSTATPTSTLRTAPPPKVLTT 2634

Query: 679  ----PSVSQSHHLFSSILPSTRASVHLLKSTSDASTPWSSSPSPLPVSLTTSTSAPLSVS 734
                P+V+ S    SS  P T  ++  L+ST  A+TP ++S +P+P S   +T   LS  
Sbjct: 2635 TATTPTVTSSKATPSSS-PGTATALPALRST--ATTPTATSVTPIPSSSLGTTWTRLS-- 2689

Query: 735  QTTLPQSSSTPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADLKSQS--TPHQEKV--- 789
            QTT P ++ +   P +  TP T+  ++ +T+  T   ++ +    S +  T H  KV   
Sbjct: 2690 QTTTPTATMSTATPSS--TPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTT 2747

Query: 790  ------ITESKSPSLVSLPTESTKAVTTNSPLPPSLTESSTEQTLPATSTNLAQMSPTFT 843
                   T S SP     P       TT +    ++T SS    +P T T+ A +  T T
Sbjct: 2748 TTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSS----IPGT-THTATVLTTTT 2802

Query: 844  TTILKTSQPLMTTPGTLSSTASLVTGPIAVQTTAGKQLSLTHPEILVPQ--ISTEGGIST 901
            TT+   S    ++    S T      P  + TT G+ L  + P  +      +T G + T
Sbjct: 2803 TTVATGSMATPSSSTQTSGTTHTPPVPNTMATTHGRSLPPSSPHTVRTAWTSATSGILGT 2862

Query: 902  ERNRVIVDATTGLIPLTSVPTSAKEMTTKLGVTAEYSP--ASRSLGTSPSPQTTVVSTAE 959
                 I + +T    +TS   +A   TT+    A  SP  +SR+  + PSP TT      
Sbjct: 2863 TH---ITEPST----VTSHTLAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTT 2915

Query: 960  DLAPKSATFAVQSSTQSPTTVSSS 983
              +  +AT A  S T++ T + SS
Sbjct: 2916 ATSRTTAT-ATPSKTRTSTLLPSS 2938



 Score = 72.0 bits (175), Expect = 4e-12
 Identities = 166/739 (22%), Positives = 270/739 (36%), Gaps = 115/739 (15%)

Query: 193  ATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTASEMGTERAMGLSEEWTV--HS 250
            AT LT+ +  +A+ S+  PSSS++           SGT         M  +   ++   S
Sbjct: 2795 ATVLTTTTTTVATGSMATPSSSTQ----------TSGTTHTPPVPNTMATTHGRSLPPSS 2844

Query: 251  QEATTSAWSPSFLPALEMGELTTPSRKRNS-----------SGPDLSWLHFYRTAASSPL 299
                 +AW+ +    L    +T PS   +            S P LS  H       SP 
Sbjct: 2845 PHTVRTAWTSATSGILGTTHITEPSTVTSHTLAATTGTTQHSTPALSSPHPSSRTTESPP 2904

Query: 300  LDLSSSSESTEKLNNSTGLQSSSVSQTKTM--------HVATVFTDG-GPRTLRSLTVSL 350
               +++   T   + +T   + S ++T T+         + TV T G  P+   S  +  
Sbjct: 2905 SPGTTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTMGCEPQCAWSEWLDY 2964

Query: 351  G-PVSKTEG--FPKDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGL 407
              P+    G  F   S I     +V   P  +E R  ++  G P  E         +FGL
Sbjct: 2965 SYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQ-PGVPLRELGQVVECSLDFGL 3023

Query: 408  TSLRWQNDSPTFGEHQLASSSEVQ----NGSPMSQTETVSRSVAPMRGGEITAHWLLTNS 463
                   +    G+ ++  + E++    N      T   S +  P      T  W+LT  
Sbjct: 3024 VC----RNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAMPSSTPGTT--WILTEL 3077

Query: 464  TTSADVTGSSASYPEGVNASVLTQFSDSTVQSGGSHTALGDRSYSESSSTSSSESLNSSA 523
            TT+A  T S+ S               +T  S    T +          T  S +   + 
Sbjct: 3078 TTTATTTESTGS--------------TATPSSTPGTTWI---------LTEPSTTATVTV 3114

Query: 524  PRGERSIAGISYGQVRGTAIEQRTSSDHTDHTYLSSTFTK-GERALLSITDNSSSSDIVE 582
            P G  + A       + TA     S+  T  T  SS  T        +      S+    
Sbjct: 3115 PTGSTATAS----STQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTP 3170

Query: 583  SSTSYIKISNSSHSEYSSFFHAQTERSNISSYDGEYAQPSTESPVLHTSNLPSYTPTINM 642
            ++TS+  I +SS                + +     +Q +T +  + T+  PS TP    
Sbjct: 3171 TATSFTAIPSSS----------------LGTTWTRLSQTTTPTATMSTAT-PSSTP--ET 3211

Query: 643  PNTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSILPSTRASVHLL 702
             +TS VL T A     + S ++ SS+  ++     L + +       S  P T  ++ + 
Sbjct: 3212 VHTSTVLTTTATTTGATGSVATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGTARTLPVW 3271

Query: 703  KSTSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQSSSTPVLPRARETPVTSFQTST 762
             ST+   T   S+ +P  +  TT T   L+ + TT+   S          TP +S QTS 
Sbjct: 3272 ISTTTTPTTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGSMA--------TPSSSTQTSG 3323

Query: 763  MTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTES 822
             T    + +++ T   +S S      V T   S +  +L T      +T +   P+ T  
Sbjct: 3324 TTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTG 3383

Query: 823  STEQTLPATSTNLAQMSPTFTTTILKTSQPLMTTPGTLSSTASLVTGPIAVQTTAGKQLS 882
            +T+ + PA    L+   P+  TT    S P  TTPG   +T+         +TTA    S
Sbjct: 3384 TTQHSTPA----LSSPHPSSRTTESPPS-PGTTTPGHTRATS---------RTTATATPS 3429

Query: 883  LTHPEILVPQISTEGGIST 901
             T    L+P   T   I+T
Sbjct: 3430 KTRTSTLLPSSPTSAPITT 3448



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 164/733 (22%), Positives = 256/733 (34%), Gaps = 128/733 (17%)

Query: 173  SGSSSRTNFTILPVGYSLEIATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTAS 232
            S    R   T  P    LE AT  T+Q    A  S   P+SS        A  T   T S
Sbjct: 2292 SDDHCRGRATTPPPTTELETATTTTTQ----ALFSTPQPTSSPGLTRAPPASTTAVPTLS 2347

Query: 233  EMGTERAMGLSEEWTVHSQEATTSAWSPS-FLPALEMGELTTPSRKRNSSGPDLSW---- 287
            E G       S   T  +   TT A S    +P +    L T S    ++G   +W    
Sbjct: 2348 E-GLTSPRYTSTLGTATTGGPTTPAGSTEPTVPGVATSTLPTRSALPGTTGSLGTWRPSQ 2406

Query: 288  ---LHFYRTAASSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLR 344
               L     A S      ++S+ S E L  S     +S   T     +T  T+     L 
Sbjct: 2407 PPTLAPTTMATSRARPTGTASTASKEPLTTSLAPTLTSELSTSQAETSTPRTETTMSPLT 2466

Query: 345  SLTVSLGPV------SKTEGFPKD--------------SRIATTSSSVLLSPSAVESRRN 384
            + T S G          TE F  D                I      +  +P ++E R  
Sbjct: 2467 NTTTSQGTTRCQPKCEWTEWFDVDFPTSGVAGGDMETFENIRAAGGKMCWAPKSIECRA- 2525

Query: 385  SRVTGNPGDEEFIEPSTENEFGL------TSLRWQNDSPTFGEHQLASSSEVQ-----NG 433
                     E + E S +    +      T L  +N+  T G   +  +  V+     + 
Sbjct: 2526 ---------ENYPEVSIDQVGQVLTCSLETGLTCKNEDQT-GRFNMCFNYNVRVLCCDDY 2575

Query: 434  SPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADVTGSSASYPEGVNASVLTQFSDSTV 493
            S    T   S +  P      T  W+LT  TT+A  T S+ S          T    ST+
Sbjct: 2576 SHCPSTPATSSTATPSSTPGTT--WILTKPTTTATTTASTGS----------TATPTSTL 2623

Query: 494  QSGGSHTALGDRSYSESSSTSSSESLNSSAPRGERSIAGISYGQVRGTAIEQR---TSSD 550
            ++      L   + + + + +SS++  SS+P    ++  +       TA       +SS 
Sbjct: 2624 RTAPPPKVL--TTTATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSVTPIPSSSL 2681

Query: 551  HTDHTYLSSTFTKGERALLSITDNSSSSDIVESSTSYIKISNSSHSEYSSFFHAQTERSN 610
             T  T LS T T    A +S    SS+ +   +ST                    T  + 
Sbjct: 2682 GTTWTRLSQTTTP--TATMSTATPSSTPETAHTST------------------VLTATAT 2721

Query: 611  ISSYDGEYAQPSTESPVLHTSNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSSSSSS 670
             +   G  A PS+     HT+ +P+ T T                     +++ SSS  +
Sbjct: 2722 TTGATGSVATPSSTPGTAHTTKVPTTTTT-------------------GFTATPSSSPGT 2762

Query: 671  SSGPPLPLPSVSQSHHLFSSILPS-----TRASVHLLKSTSDASTPWSSSPSPLPVSLTT 725
            +  PP+ + + +      S++ PS     T  +  L  +T+  +T   ++PS    +  T
Sbjct: 2763 ALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGT 2822

Query: 726  STSAPLSVSQTTLPQSSSTPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADLKSQSTPH 785
            + + P+  +  T    S  P  P    T  TS  +  + +      S+ T+   + +T  
Sbjct: 2823 THTPPVPNTMATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTLAATTGT 2882

Query: 786  QEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESSTEQTLPATSTNLAQMSPTFTTT 845
             +       SP   S  TES        P P + T   T  T   T+T  A  S T T+T
Sbjct: 2883 TQHSTPALSSPHPSSRTTES-------PPSPGTTTPGHTTATSRTTAT--ATPSKTRTST 2933

Query: 846  IL---KTSQPLMT 855
            +L    TS P+ T
Sbjct: 2934 LLPSSPTSAPITT 2946



 Score = 51.2 bits (121), Expect = 7e-06
 Identities = 132/630 (20%), Positives = 218/630 (34%), Gaps = 86/630 (13%)

Query: 439  TETVSRSVAPMRGGEITAHWLLTNSTTSADVTGSSA---SYPEGVNAS-VLTQFSDSTVQ 494
            T   + SV P+    +   W   + TT+   T S+A   S PE  + S VLT  + +T  
Sbjct: 2666 TTPTATSVTPIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTATATTTGA 2725

Query: 495  SGGSHTALGDRSYSESSSTSSSESLNSSAPRGERSIAGISYGQVRGTAIEQRTSSDHTDH 554
            +G   T       S +  T+ +  + ++   G  +    S G      +   T++  T  
Sbjct: 2726 TGSVATP------SSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTR 2779

Query: 555  ----TYLSSTFTKGERALLSITDNSSSSDIVESSTSYIKISNSSHSEYSSFFHAQTERSN 610
                T  S   T     +L+ T  + ++  + + +S  + S ++H+       A T   +
Sbjct: 2780 GSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTTHTPPVPNTMATTHGRS 2839

Query: 611  I---SSYDGEYAQPSTESPVLHTSNL--PSYTPTINMPNTSVVLDTDAEFVSDSSSSSSS 665
            +   S +    A  S  S +L T+++  PS   +  +  T+         +S    SS +
Sbjct: 2840 LPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTLAATTGTTQHSTPALSSPHPSSRT 2899

Query: 666  SSSSSSSGPPLPLPSVSQSHHLFSSILPSTRASVHLLKSTSDA------------STPWS 713
            + S  S G   P  + + S    ++    TR S  L  S + A               WS
Sbjct: 2900 TESPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTMGCEPQCAWS 2959

Query: 714  -----SSPSPLPVSLTTSTSAPL-----SVSQTTLPQSSSTPVLPRARETPVTSFQTSTM 763
                 S P P P      T + +     +V +  L         P      +      ++
Sbjct: 2960 EWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQVVECSL 3019

Query: 764  TSFMTMLHSSQTADLKS----------------QSTPHQEKVITESKSPS----LVSLPT 803
               +   +  Q    K                  STP        S +P     L  L T
Sbjct: 3020 DFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAMPSSTPGTTWILTELTT 3079

Query: 804  ESTKAVTTNSPLPPS--------LTESSTEQTLPATSTNLAQMSPTFTTTILKTSQPLMT 855
             +T   +T S   PS        LTE ST  T+   + + A  S T  T          T
Sbjct: 3080 TATTTESTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTAT 3139

Query: 856  TPGTLSSTASLVTGPIAVQTTAGKQLSLTHPEILVPQISTEGGISTERNRVIVDATTGLI 915
            TP   SS A+  + P         + + T P            + T   R+    T    
Sbjct: 3140 TPTVTSSKATPFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTAT 3199

Query: 916  PLTSVPTSAKE---MTTKLGVTAEYSPASRSLGT-SPSPQT-------TVVSTAEDLAPK 964
              T+ P+S  E    +T L  TA  + A+ S+ T S +P T       T  +T     P 
Sbjct: 3200 MSTATPSSTPETVHTSTVLTTTATTTGATGSVATPSSTPGTAHTTKVLTTTTTGFTATPS 3259

Query: 965  SATFAVQ------SSTQSPTTVSSSASVNS 988
            S+    +      S+T +PTT  S+ + +S
Sbjct: 3260 SSPGTARTLPVWISTTTTPTTRGSTVTPSS 3289



 Score = 36.6 bits (83), Expect = 0.17
 Identities = 54/190 (28%), Positives = 74/190 (38%), Gaps = 40/190 (21%)

Query: 827  TLPATSTNLAQMSPTFTTTILKTSQPLMTTPG-------------TLSS--TASLVTGPI 871
            T P  +T L   + T T  +  T QP  ++PG             TLS   T+   T  +
Sbjct: 2301 TTPPPTTELETATTTTTQALFSTPQP-TSSPGLTRAPPASTTAVPTLSEGLTSPRYTSTL 2359

Query: 872  AVQTTAGKQLSLTHPEILVPQISTEGGISTERNRVIVDATTGLI-------PLTSVPTSA 924
               TT G        E  VP ++T    ST   R  +  TTG +       P T  PT+ 
Sbjct: 2360 GTATTGGPTTPAGSTEPTVPGVAT----STLPTRSALPGTTGSLGTWRPSQPPTLAPTTM 2415

Query: 925  KEMTTKLGVTAEYSPASRS-LGTSPSPQTT---VVSTAEDLAPKSATFAVQSSTQSP-TT 979
               T++   T   S AS+  L TS +P  T     S AE   P++ T      T SP T 
Sbjct: 2416 --ATSRARPTGTASTASKEPLTTSLAPTLTSELSTSQAETSTPRTET------TMSPLTN 2467

Query: 980  VSSSASVNSC 989
             ++S     C
Sbjct: 2468 TTTSQGTTRC 2477


>gi|239758038 PREDICTED: mucin 3A, cell surface associated, partial
            [Homo sapiens]
          Length = 909

 Score =  105 bits (262), Expect = 3e-22
 Identities = 216/939 (23%), Positives = 351/939 (37%), Gaps = 180/939 (19%)

Query: 230  TASEMGTERAMGLSEEWTVHSQEATTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLH 289
            T SE  + R    +   T      T S+ +PSF  ++   E T+ S    +S    +   
Sbjct: 2    TTSETPSHRTPSFTSSITTTE---TPSSSTPSFTSSITTTETTSHSTPSFTSSISTTETT 58

Query: 290  FYRTAASSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVS 349
             + T + + L+ +      TE  ++ST   ++S++ T+T   +T      P    S+T +
Sbjct: 59   SHSTPSFTSLITI------TETTSHSTPSYTTSITTTETPSHST------PSYTTSITTT 106

Query: 350  LGPVSKTEGFPKDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTS 409
              P   T  F   S I TT ++   +PS   S R +  T       F   +T  E   TS
Sbjct: 107  ETPSHSTPSFT--SSITTTETTSHSTPSFTSSIRTTETTSY-STPSFTSSNTITE--TTS 161

Query: 410  LRWQNDSPTFGEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADV 469
                +   +    +  SSS     S ++ TET S S               T+S T+ + 
Sbjct: 162  HSTPSYITSITTTETPSSSTPSFSSSITTTETTSHSTPGF-----------TSSITTTET 210

Query: 470  TGSSASYPEGVNASVLTQFSDSTVQSGGSHTALGDRSYSESSSTSSSESLNSSAPRGERS 529
            T  S        +S+ T  +++T     S T+    S + S ST SS SL ++      S
Sbjct: 211  TSHSTP---SFTSSITT--TETTSHDTPSFTSSITTSETPSHSTPSSTSLITTTKTTSHS 265

Query: 530  IAGISYGQVRGTAIEQRTSSDHTDHTYLSS-----TFTKGERALLS-ITDNSSSSDIVES 583
                +      ++I    ++ H+ H++ SS     T +   R+  S IT   ++S    S
Sbjct: 266  TPSFT------SSITTTETTSHSAHSFTSSITTTETTSHNTRSFTSSITTTETNSHSTTS 319

Query: 584  STSYIKISNSSHSEYSSFFHAQTERSNISSYDGEYAQ---------PSTESPVLHTSNLP 634
             TS I  + ++     SF  + T            ++         PS+ S  + T++L 
Sbjct: 320  FTSSITTTETTSHSTPSFSSSITTTETXXXXXXXTSETAVTPTPVTPSSLSTDIPTTSLR 379

Query: 635  SYTPTINMPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSILPS 694
            + TP+    +TS+   TD   +    S+  + +   SS P +     S      S  + +
Sbjct: 380  TLTPSSVGTSTSLTTTTDFPSIPTDISTLPTRTHIISSSPSIQSTETSSLVGTTSPTMST 439

Query: 695  TRASVHLLKSTSDAS----------TPWSSSP----------SPLPVSLT---------- 724
             R ++ + ++T  +S          TP  + P          SP P ++T          
Sbjct: 440  VRMTLRITENTPISSFSTSIVVIPETPTQTPPVLTSATGTQTSPAPTTVTFGSTDSSTST 499

Query: 725  -------TSTSAPLSVSQTTLPQSSS-----TPVLPRARE--TPVTSFQTST-------- 762
                   T+ S  +S SQ  +P + S     TP  P  +   T  + F T +        
Sbjct: 500  LHTLTPSTALSTIVSTSQVPIPSTHSSTLQTTPSTPSLQTSLTSTSEFTTESFTRGSTST 559

Query: 763  ---MTSFMTMLHSSQTADLKSQS------TPHQEKVI-----------TESK-SPSLVSL 801
               +TSF T++ SS    + S S      TP     I           TE+  S S+   
Sbjct: 560  NAILTSFSTIIWSSTPTIIMSSSPSSASITPVFSTTIHSVPSSPYIFSTENVGSASITGF 619

Query: 802  PTESTKAVTTNSPLPPSLTESSTEQTLPATSTNLAQMSP---TFTTTILKTS--QPLM-- 854
            P+ S+ A T+ S    SLT + TE T P +  +L   +P   T T TI+  S   P +  
Sbjct: 620  PSLSSSATTSTSSTSSSLTTALTEIT-PFSYISLPSTTPCPGTITITIVPASPTDPCVEM 678

Query: 855  ----------TTPGTLSS-TASLVTGP--IAVQTTAGKQLSLTH--PEI---LVPQISTE 896
                      TTP T+   T  +VT P  I++QTT    +  +   PE    + P  S+ 
Sbjct: 679  DPSTEATSPPTTPLTVFPFTTEMVTCPTSISIQTTLTTYMDTSSMMPESESSISPNASSS 738

Query: 897  GGISTERNRVIVDAT-----------TGLIPLTSVPTSAKEMTTKLGVTAEYSPASRSLG 945
             G  T     +  +T           + +IPL     S   +T K   +      + S  
Sbjct: 739  TGTGTVPTNTVFTSTRLPTSETWLSNSSVIPLPLPGVSTIPLTMKPSSSLPTILRTSSKS 798

Query: 946  TSPSPQTTVVSTAEDLAPKSATFAVQSSTQSPTTVSSSASVNSCAVNPCLHNGECVADNT 1005
            T PSP TT  S       ++ T      T   T+  ++ S  +     C + G      T
Sbjct: 799  THPSPPTTRTSETPVATTQTPTTLTSRRTTRITSQMTTQSTLTTTAGTCDNGG------T 852

Query: 1006 SRGYHCRCPPSWQGDDCSVDVN-------ECLSNPCPST 1037
                 C C P + GD C +          + L   CPST
Sbjct: 853  WEQGQCACLPGFSGDRCQLQTRCQNGGQWDGLKCQCPST 891



 Score = 81.6 bits (200), Expect = 5e-15
 Identities = 184/791 (23%), Positives = 302/791 (38%), Gaps = 101/791 (12%)

Query: 146 TSGKSHAASDAPENLTLLAETADARGRSGSSSRTNFTI---LPVGYSLEIATALTSQSGN 202
           T   SH+      ++T    T+ +     SS RT  T     P   S    T  TS S  
Sbjct: 106 TETPSHSTPSFTSSITTTETTSHSTPSFTSSIRTTETTSYSTPSFTSSNTITETTSHSTP 165

Query: 203 LASESL---HLPSSSS-EFDERIAAFQTKSG-----TASEMGTERAMGLSEEWTVH-SQE 252
               S+     PSSS+  F   I   +T S      T+S   TE     +  +T   +  
Sbjct: 166 SYITSITTTETPSSSTPSFSSSITTTETTSHSTPGFTSSITTTETTSHSTPSFTSSITTT 225

Query: 253 ATTSAWSPSFLPALEMGE-----------LTTPSRKRNSSGPDLSWLHFYRTAASSPLLD 301
            TTS  +PSF  ++   E           L T ++  + S P  +         S     
Sbjct: 226 ETTSHDTPSFTSSITTSETPSHSTPSSTSLITTTKTTSHSTPSFTSSITTTETTSHSAHS 285

Query: 302 LSSSSESTEKLNNSTGLQSSSVSQTKT-MHVATVFTDGGPRTLRSLTVSLGPVSKTEGFP 360
            +SS  +TE  +++T   +SS++ T+T  H  T FT        S+T +      T  F 
Sbjct: 286 FTSSITTTETTSHNTRSFTSSITTTETNSHSTTSFTS-------SITTTETTSHSTPSF- 337

Query: 361 KDSRIATT---------SSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGL-TSL 410
             S I TT         +S   ++P+ V    +S  T  P     +   T +  G  TSL
Sbjct: 338 -SSSITTTETXXXXXXXTSETAVTPTPVTP--SSLSTDIPTTS--LRTLTPSSVGTSTSL 392

Query: 411 RWQNDSPTFGE---------HQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLT 461
               D P+            H ++SS  +Q+    S   T S +++ +R   +T    +T
Sbjct: 393 TTTTDFPSIPTDISTLPTRTHIISSSPSIQSTETSSLVGTTSPTMSTVR---MTLR--IT 447

Query: 462 NSTTSADVTGSSASYPEGVNASVLTQFSDSTVQSGGSHTALGDRSYSESSSTSSSESLNS 521
            +T  +  + S    PE       TQ       + G+ T+    + +  S+ SS+ +L++
Sbjct: 448 ENTPISSFSTSIVVIPE-----TPTQTPPVLTSATGTQTSPAPTTVTFGSTDSSTSTLHT 502

Query: 522 SAPRGERSIAGISYGQV----RGTAIEQRTSSDHTDHTYLSST-------FTKGERALLS 570
             P    S   +S  QV      ++  Q T S  +  T L+ST       FT+G  +  +
Sbjct: 503 LTPSTALSTI-VSTSQVPIPSTHSSTLQTTPSTPSLQTSLTSTSEFTTESFTRGSTSTNA 561

Query: 571 ITDNSSSSDIVESSTSYIKISNSSHSE-----YSSFFHAQTERSNISSYDGEYAQPSTES 625
           I   +S S I+ SST  I +S+S  S      +S+  H+      I S +   +   T  
Sbjct: 562 IL--TSFSTIIWSSTPTIIMSSSPSSASITPVFSTTIHSVPSSPYIFSTENVGSASITGF 619

Query: 626 PVLHTSNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPL-PSVSQS 684
           P L +S   S + T +   T++   T   ++S  S++    + + +  P  P  P V   
Sbjct: 620 PSLSSSATTSTSSTSSSLTTALTEITPFSYISLPSTTPCPGTITITIVPASPTDPCVEMD 679

Query: 685 HHLFSSILPSTRASVHLLKSTSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQSSST 744
               ++  P+T  +V           P+++     P S++  T+    +  +++   S +
Sbjct: 680 PSTEATSPPTTPLTVF----------PFTTEMVTCPTSISIQTTLTTYMDTSSMMPESES 729

Query: 745 PVLPRARETPVTSFQTSTMTSFMTMLHSSQTADLKSQSTPHQ---EKVITESKSPSLVSL 801
            + P A  +  T    +      T L +S+T    S   P        I  +  PS  SL
Sbjct: 730 SISPNASSSTGTGTVPTNTVFTSTRLPTSETWLSNSSVIPLPLPGVSTIPLTMKPSS-SL 788

Query: 802 PTESTKAVTTNSPLPPSLTESSTEQTLPATSTNLAQMSPTFTTTILKTSQPLMTTPGTLS 861
           PT    +  +  P PP+   S T      T T L     T  T+ + T   L TT GT  
Sbjct: 789 PTILRTSSKSTHPSPPTTRTSETPVATTQTPTTLTSRRTTRITSQMTTQSTLTTTAGTCD 848

Query: 862 STASLVTGPIA 872
           +  +   G  A
Sbjct: 849 NGGTWEQGQCA 859


>gi|239743291 PREDICTED: mucin 3A, intestinal [Homo sapiens]
          Length = 1486

 Score =  105 bits (261), Expect = 4e-22
 Identities = 211/953 (22%), Positives = 353/953 (37%), Gaps = 114/953 (11%)

Query: 150  SHAASDAPENLTLLAETADARGRSGSSSRTNFTILPVGYSLEIATALTSQSGNLASESLH 209
            S  +++   ++T  A    A     S +RT  +  PV  S E  T+  + +  L++    
Sbjct: 262  SITSTNTVTSMTTTASQPTATNTLSSPTRTILSSTPV-LSTETITSGITNTTPLSTLVTT 320

Query: 210  LPSSSSEFDERIAAFQTKSGTASEMGTERAMGLSEEWTVHSQEATTSAWSPSFLPALEMG 269
            LP++ S            S T++   +   +  S   T      T+   + S LP  E  
Sbjct: 321  LPTTISRSTPTSETTYPTSPTSTVTDSTTKIAYSTSMTGTLSTETSLPPTSSSLPTTETA 380

Query: 270  E------LTTPSRKRNSSGPDLSWLHFYRTAASSPLLDLSSSSESTEKLNNSTGLQSSSV 323
                   +TT +   + S P  S    Y T  S      +SS  +TE  ++ST   +SS 
Sbjct: 381  TTPMTNLVTTTTEISSHSTPSFSSSTIYSTVTSHSTPRFTSSITTTETPSHSTPRFTSSF 440

Query: 324  SQTKTM-HVATVFTDGGPRTLRSLTVSLGPVSKTEGFPKDSRIATTSSSVLLSPSAVESR 382
            + TKT  H +  FT        SL  +    S +   P  +   TT+ +   S  +  S 
Sbjct: 441  TNTKTTSHRSPSFT--------SLITTTETTSHST--PSFTSSITTTETTSHSARSFTSS 490

Query: 383  RNSRVTGNPGDEEFIEPSTENEFGLTSLRWQNDSPTFGEHQLASSSEVQNGSPMSQTETV 442
              +  T +     F    T  E         N   T       +++E  + S  S + ++
Sbjct: 491  ITTTETTSHNTRSFTSSITTTE--------TNSHSTTSFTSSITTTETTSHSTPSFSSSI 542

Query: 443  SRSVAPMRGGEITAHWLLTNSTTSADVTGSSASYPEGVNASVLTQFSDSTVQSGGSHTAL 502
            + +  P+        W+ T  TTS            G+ +S+ T  + S    G + +  
Sbjct: 543  TTTETPLHSTPGLTSWVTTTKTTS--------HITPGLTSSITTTETTSHSTPGFTSSIT 594

Query: 503  GDRSYSESSSTSSSESLNSSAPRGERSIAGISYGQVRGTAIEQR--TSSDHTDHTYLSST 560
               + SES+ + SS ++ S+      +I   S+     TA+     T S  +     +S 
Sbjct: 595  TTETTSESTPSLSSSTIYSTVSTSTTAIT--SHFTTSETAVTPTPVTPSSLSTDIPTTSL 652

Query: 561  FTKGERALLSITDNSSSSDIVESSTSYIKISNSSHSEYSSFFHAQTERSNISSYDGEYAQ 620
             T    ++ + T  ++++D     T    +   +H   SS     TE S++         
Sbjct: 653  RTLTPSSVGTSTSLTTTTDFPSIPTDISTLPTRTHIISSSPSIQSTETSSLVG-----TT 707

Query: 621  PSTESPVLHTSNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPS 680
              T S V  T  +   TP I+  +TS+V+  +    +    +S++ + +S +   +   S
Sbjct: 708  SPTMSTVRMTLRITENTP-ISSFSTSIVVIPETPTQTPPVLTSATGTQTSPAPTTVTFGS 766

Query: 681  VSQSHHLFSSILPSTRASVHLLKSTSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQ 740
               S     ++ PST  S   + STS    P + S +     L T+ S P   +  T   
Sbjct: 767  TDSSTSTLHTLTPSTALST--IVSTSQVPIPSTHSST-----LQTTPSTPSLQTSLTSTS 819

Query: 741  SSSTPVLPRARETP---VTSFQTSTMTSFMTMLHSSQTADLKS--------QSTPHQEKV 789
              +T    R   +    +TSF T   +S  T++ SS  +             S P    +
Sbjct: 820  EFTTESFTRGSTSTNAILTSFSTIIWSSTPTIIMSSSPSSASITPVFSTTIHSVPSSPYI 879

Query: 790  ITESK--SPSLVSLPTESTKAVTTNSPLPPSLTESSTEQTLPATSTNLAQMSP---TFTT 844
             +     S S+   P+ S+ A T+ S    SLT + TE T P +  +L   +P   T T 
Sbjct: 880  FSTENVGSASITGFPSLSSSATTSTSSTSSSLTTALTEIT-PFSYISLPSTTPCPGTITI 938

Query: 845  TILKTS--QPLM------------TTPGTLSS-TASLVTGP--IAVQTTAGKQLSLTH-- 885
            TI+  S   P +            TTP T+   T  +VT P  I++QTT    +  +   
Sbjct: 939  TIVPASPTDPCVEMDPSTEATSPPTTPLTVFPFTTEMVTCPTSISIQTTLTTYMDTSSMM 998

Query: 886  PEI---LVPQISTEGGISTERNRVIVDAT-----------TGLIPLTSVPTSAKEMTTKL 931
            PE    + P  S+  G  T     +  +T           + +IPL     S   +T K 
Sbjct: 999  PESESSISPNASSSTGTGTVPTNTVFTSTRLPTSETWLSNSSVIPLPLPGVSTIPLTMKP 1058

Query: 932  GVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSATFAVQSSTQSPTTVSSSASVNSCAV 991
              +      + S  T PSP TT  S       ++ T      T   T+  ++ S  +   
Sbjct: 1059 SSSLPTILRTSSKSTHPSPPTTRTSETPVATTQTPTTLTSRRTTRITSQMTTQSTLTTTA 1118

Query: 992  NPCLHNGECVADNTSRGYHCRCPPSWQGDDCSVDVN-------ECLSNPCPST 1037
              C + G      T     C C P + GD C +          + L   CPST
Sbjct: 1119 GTCDNGG------TWEQGQCACLPGFSGDRCQLQTRCQNGGQWDGLKCQCPST 1165



 Score = 81.6 bits (200), Expect = 5e-15
 Identities = 187/817 (22%), Positives = 315/817 (38%), Gaps = 94/817 (11%)

Query: 96   SGRAPRGGSADAAWKHWPESNTEAHVENITFYQNQEDFSTVSSKE-----GVMVQTSGKS 150
            S   P   +A     +   + TE    +   + +   +STV+S         +  T   S
Sbjct: 371  SSSLPTTETATTPMTNLVTTTTEISSHSTPSFSSSTIYSTVTSHSTPRFTSSITTTETPS 430

Query: 151  HAASDAPENLTLLAETADARGRSGSS----SRTNFTILPVGYSLEIATALTSQSGNLASE 206
            H+      + T   +T   R  S +S    + T     P   S    T  TS S    + 
Sbjct: 431  HSTPRFTSSFTN-TKTTSHRSPSFTSLITTTETTSHSTPSFTSSITTTETTSHSARSFTS 489

Query: 207  SLHLPSSSSEFDERIAAFQTKSGTASEMGTERAMGLSEEWTVH-SQEATTSAWSPSFLPA 265
            S+    ++S          T+S T+S   TE     +  +T   +   TTS  +PSF   
Sbjct: 490  SITTTETTSH--------NTRSFTSSITTTETNSHSTTSFTSSITTTETTSHSTPSF--- 538

Query: 266  LEMGELTTPSRKRNSSGPDLSWLHFYRTAASSPLLDLSSSSESTEKLNNSTGLQSSSVSQ 325
                 +TT     +S+    SW+   +T  S     L+SS  +TE  ++ST   +SS++ 
Sbjct: 539  --SSSITTTETPLHSTPGLTSWVTTTKTT-SHITPGLTSSITTTETTSHSTPGFTSSITT 595

Query: 326  TKTMHVATVFTDGGPRTLRSLTVSLGPVSKTEGFPKDSRIATTSSSVLLSPSAVESRRNS 385
            T+T   +T        T+ S TVS    + T  F        T+S   ++P+ V    +S
Sbjct: 596  TETTSESTPSLSSS--TIYS-TVSTSTTAITSHF--------TTSETAVTPTPVTP--SS 642

Query: 386  RVTGNPGDEEFIEPSTENEFGL-TSLRWQNDSPTFGE---------HQLASSSEVQNGSP 435
              T  P     +   T +  G  TSL    D P+            H ++SS  +Q+   
Sbjct: 643  LSTDIPTTS--LRTLTPSSVGTSTSLTTTTDFPSIPTDISTLPTRTHIISSSPSIQSTET 700

Query: 436  MSQTETVSRSVAPMRGGEITAHWLLTNSTTSADVTGSSASYPEGVNASVLTQFSDSTVQS 495
             S   T S +++ +R   +T    +T +T  +  + S    PE       TQ       +
Sbjct: 701  SSLVGTTSPTMSTVR---MTLR--ITENTPISSFSTSIVVIPE-----TPTQTPPVLTSA 750

Query: 496  GGSHTALGDRSYSESSSTSSSESLNSSAPRGERSIAGISYGQV----RGTAIEQRTSSDH 551
             G+ T+    + +  S+ SS+ +L++  P    S   +S  QV      ++  Q T S  
Sbjct: 751  TGTQTSPAPTTVTFGSTDSSTSTLHTLTPSTALSTI-VSTSQVPIPSTHSSTLQTTPSTP 809

Query: 552  TDHTYLSST-------FTKGERALLSITDNSSSSDIVESSTSYIKISNSSHSE-----YS 599
            +  T L+ST       FT+G  +  +I   +S S I+ SST  I +S+S  S      +S
Sbjct: 810  SLQTSLTSTSEFTTESFTRGSTSTNAIL--TSFSTIIWSSTPTIIMSSSPSSASITPVFS 867

Query: 600  SFFHAQTERSNISSYDGEYAQPSTESPVLHTSNLPSYTPTINMPNTSVVLDTDAEFVSDS 659
            +  H+      I S +   +   T  P L +S   S + T +   T++   T   ++S  
Sbjct: 868  TTIHSVPSSPYIFSTENVGSASITGFPSLSSSATTSTSSTSSSLTTALTEITPFSYISLP 927

Query: 660  SSSSSSSSSSSSSGPPLPL-PSVSQSHHLFSSILPSTRASVHLLKSTSDASTPWSSSPSP 718
            S++    + + +  P  P  P V       ++  P+T  +V           P+++    
Sbjct: 928  STTPCPGTITITIVPASPTDPCVEMDPSTEATSPPTTPLTVF----------PFTTEMVT 977

Query: 719  LPVSLTTSTSAPLSVSQTTLPQSSSTPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADL 778
             P S++  T+    +  +++   S + + P A  +  T    +      T L +S+T   
Sbjct: 978  CPTSISIQTTLTTYMDTSSMMPESESSISPNASSSTGTGTVPTNTVFTSTRLPTSETWLS 1037

Query: 779  KSQSTPHQ---EKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESSTEQTLPATSTNL 835
             S   P        I  +  PS  SLPT    +  +  P PP+   S T      T T L
Sbjct: 1038 NSSVIPLPLPGVSTIPLTMKPSS-SLPTILRTSSKSTHPSPPTTRTSETPVATTQTPTTL 1096

Query: 836  AQMSPTFTTTILKTSQPLMTTPGTLSSTASLVTGPIA 872
                 T  T+ + T   L TT GT  +  +   G  A
Sbjct: 1097 TSRRTTRITSQMTTQSTLTTTAGTCDNGGTWEQGQCA 1133



 Score = 79.7 bits (195), Expect = 2e-14
 Identities = 121/483 (25%), Positives = 198/483 (40%), Gaps = 64/483 (13%)

Query: 555 TYLSSTFTKGERALLSITDNSSSSDIVESSTSYIKISNSSHSEYSSFFHAQ-------TE 607
           TY  +T  KG  A+      SS S      T  + ++ SS S   + FH         TE
Sbjct: 173 TYSMTTTEKGTSAM-----TSSPSTTTARETPIVTVTPSSVSATDTTFHTTISSTTRTTE 227

Query: 608 RSNISSYDGEYAQPSTESPVLHT-----SNLPSYTPTINMPNTSVVLDTDAEFVSDSSSS 662
           R+ + +  G     ++ +PV  T     ++    T +I   NT   + T A   + +++ 
Sbjct: 228 RTPLPT--GSIHTTTSPTPVFTTLKTAVTSTSPITSSITSTNTVTSMTTTASQPTATNTL 285

Query: 663 SSSSSSSSSSGPPLPLPSVSQSHHLFSSILPSTRAS--VHLLKSTSDASTPWSSSPSPL- 719
           SS + +  SS P L   +++      S I  +T  S  V  L +T   STP S +  P  
Sbjct: 286 SSPTRTILSSTPVLSTETIT------SGITNTTPLSTLVTTLPTTISRSTPTSETTYPTS 339

Query: 720 PVSLTTSTSAPLSVSQT-TLPQSSSTPVLPRARETPVTSFQTSTMTSFMTML-----HSS 773
           P S  T ++  ++ S + T   S+ T + P +   P T   T+ MT+ +T       HS+
Sbjct: 340 PTSTVTDSTTKIAYSTSMTGTLSTETSLPPTSSSLPTTETATTPMTNLVTTTTEISSHST 399

Query: 774 QT-------ADLKSQSTPHQEKVITESKSPSLVSLP--TESTKAVTTNSPLPPSLTE--S 822
            +       + + S STP     IT +++PS  S P  T S     T S   PS T   +
Sbjct: 400 PSFSSSTIYSTVTSHSTPRFTSSITTTETPS-HSTPRFTSSFTNTKTTSHRSPSFTSLIT 458

Query: 823 STEQTLPATSTNLAQMSPTFTTTILKTS--QPLMTTPGTLSSTASLVTGPIAVQTTAGKQ 880
           +TE T  +T +  + ++ T TT+    S    + TT  T  +T S  +     +T +   
Sbjct: 459 TTETTSHSTPSFTSSITTTETTSHSARSFTSSITTTETTSHNTRSFTSSITTTETNSHST 518

Query: 881 LSLTHPEILVPQISTEGGISTERNRVIVDATTGLIPLTSVPTSAKEMTTKL-------GV 933
            S T        I+T    S          TT   PL S P     +TT         G+
Sbjct: 519 TSFT------SSITTTETTSHSTPSFSSSITTTETPLHSTPGLTSWVTTTKTTSHITPGL 572

Query: 934 TAEYSPASRSLGTSP---SPQTTVVSTAEDLAPKSATFAVQSSTQSPTTVSSSASVNSCA 990
           T+  +    +  ++P   S  TT  +T+E     S++    + + S T ++S  + +  A
Sbjct: 573 TSSITTTETTSHSTPGFTSSITTTETTSESTPSLSSSTIYSTVSTSTTAITSHFTTSETA 632

Query: 991 VNP 993
           V P
Sbjct: 633 VTP 635



 Score = 66.2 bits (160), Expect = 2e-10
 Identities = 108/444 (24%), Positives = 182/444 (40%), Gaps = 46/444 (10%)

Query: 565 ERALLSITDNSSSSDIVESSTSYIKISNSSHSEYSSF-FHAQTERSNISSYDGEYAQPST 623
           E A +++T +   + I E+  +    SN+S +  S F F  +T    +  Y       +T
Sbjct: 72  ENAPMTLTTSPHDTLISETLLNSPVSSNTSTTPTSKFAFKVETTPPTVLVYS------AT 125

Query: 624 ESPVLHTSNLPSYTPTINMPNTSVVLDTDAEFVSDSSS-----------SSSSSSSSSSS 672
              V  TS    +  TI+ P +  V  T   F S  +S           +S+ S +++  
Sbjct: 126 TECVYPTS----FIITISHPTSICVTTTQVAFTSSYTSTPVTQKPVTTVTSTYSMTTTEK 181

Query: 673 GPPLPLPSVSQSHHLFSSILPSTRASVHLLKS---TSDASTPWSSSPSPLPVSLTTSTSA 729
           G      S S +    + I+  T +SV    +   T+ +ST  ++  +PLP     +T++
Sbjct: 182 GTSAMTSSPSTTTARETPIVTVTPSSVSATDTTFHTTISSTTRTTERTPLPTGSIHTTTS 241

Query: 730 PLSVSQTTLPQSSSTPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADLKSQSTPHQEKV 789
           P  V  T     +ST        +P+TS  TST T       +SQ     + S+P     
Sbjct: 242 PTPVFTTLKTAVTST--------SPITSSITSTNTVTSMTTTASQPTATNTLSSP----- 288

Query: 790 ITESKSPSLVSLPTES-TKAVTTNSPLPPSLTE-SSTEQTLPATSTNLAQMSPTFTTTIL 847
            T +   S   L TE+ T  +T  +PL   +T   +T      TS      SPT T T  
Sbjct: 289 -TRTILSSTPVLSTETITSGITNTTPLSTLVTTLPTTISRSTPTSETTYPTSPTSTVTDS 347

Query: 848 KTSQPLMTT-PGTLSSTASLVTGPIAVQTTAGKQLSLTHPEILVPQISTEGGISTERNRV 906
            T     T+  GTLS+  SL     ++ TT      +T+      +IS+    S   + +
Sbjct: 348 TTKIAYSTSMTGTLSTETSLPPTSSSLPTTETATTPMTNLVTTTTEISSHSTPSFSSSTI 407

Query: 907 IVDATTGLIP--LTSVPTSAKEMTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPK 964
               T+   P   +S+ T+     +    T+ ++    +   SPS  T++++T E  +  
Sbjct: 408 YSTVTSHSTPRFTSSITTTETPSHSTPRFTSSFTNTKTTSHRSPS-FTSLITTTETTSHS 466

Query: 965 SATFAVQSSTQSPTTVSSSASVNS 988
           + +F   S T + TT  S+ S  S
Sbjct: 467 TPSF-TSSITTTETTSHSARSFTS 489



 Score = 37.7 bits (86), Expect = 0.077
 Identities = 52/205 (25%), Positives = 83/205 (40%), Gaps = 31/205 (15%)

Query: 781 QSTPHQEKVITESKSPSLVSLP-TESTKAVTTNSPLPPSLTESSTEQTLPATSTNLAQMS 839
           +++P     ++ + S S V  P  E+  AV +NSP    L         P     LA  +
Sbjct: 14  KASPWATGTLSTATSISQVPFPRAEAASAVLSNSPHSRDLAG------WPLGVPQLASPA 67

Query: 840 PTFTTTILKTSQPLMTTPGTLSSTASLVTGPIAVQTTAGK------QLSLTHPEILVPQI 893
           P        T   L T+P     + +L+  P++  T+         ++  T P +LV   
Sbjct: 68  PGHRENAPMT---LTTSPHDTLISETLLNSPVSSNTSTTPTSKFAFKVETTPPTVLVYSA 124

Query: 894 STEGGISTERNRVIVDATTGLIPLTSVPTSAKEMTTKLGVTAEYSPASRSLGTSPSPQTT 953
           +TE           V  T+ +I + S PTS    TT++  T+ Y+    S   +  P TT
Sbjct: 125 TTE----------CVYPTSFIITI-SHPTSICVTTTQVAFTSSYT----STPVTQKPVTT 169

Query: 954 VVSTAEDLAPKSATFAVQSSTQSPT 978
           V ST      +  T A+ SS  + T
Sbjct: 170 VTSTYSMTTTEKGTSAMTSSPSTTT 194


>gi|151301154 mucin 6, gastric [Homo sapiens]
          Length = 2439

 Score =  104 bits (259), Expect = 7e-22
 Identities = 236/1029 (22%), Positives = 378/1029 (36%), Gaps = 150/1029 (14%)

Query: 65   PPTPPRERRGPATPGPSYRA----PEPGAATQRGP-SGRAPRGGSADAAWKHWPESNTEA 119
            PPT P+    P  P    R     P  G +T  G  S   P   S      H P S T+ 
Sbjct: 1198 PPTTPQPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSS-----NHTPASPTQT 1252

Query: 120  HVENITFYQNQEDFSTVSSKEGVMVQTSGKSHAASDAPENLTLLAETADARGRSGSSSRT 179
             +   T   ++    T SS E     T+    A S  P   TL +          ++  T
Sbjct: 1253 PLLPATLTSSKP---TASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRAT 1309

Query: 180  NFTILPVGYSLEIATALTSQS---GNLASESLHLPSSSSEFDERIAAFQTKSG------- 229
              T  P   S   +T  T+ +      +  S  LP S+++      A QT          
Sbjct: 1310 ASTASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPAST 1369

Query: 230  --------------TASEMGTERAMGLSEEWTVHSQEATTSAWSPSFLPALEMGELTTPS 275
                          TA+E    R    + E+T      TT +   +  P    G +T  S
Sbjct: 1370 TGPTTPQPGQPTRPTATETTQTRT---TTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATS 1426

Query: 276  RKRNSSGPDLSWLHFYRTAASS-PLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATV 334
                ++ P  S  H   T  +  P    S  + ST  +   T  Q ++ +     H A  
Sbjct: 1427 FHATTTYPTPS--HPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASN---HSAPT 1481

Query: 335  FTDGGPRTLRSL--TVSLGPVSKTEGFPKDSRIATTSSSVLLSPSAVESRRNSR------ 386
             T   P TL++   T +  P++ T         A +S S   +P+++ S  +S       
Sbjct: 1482 GTIPPPTTLKATGSTHTAPPITPTTSGTSQ---AHSSFSTNKTPTSLHSHTSSTHHPEVT 1538

Query: 387  ------VTGNPGDEEFIEPSTENEFGLTSLRWQNDSPTFGEHQLAS-SSEVQNGSPMSQT 439
                  +T NP       P        +S       P F  H   + SS   +  PM+ T
Sbjct: 1539 PTSTTTITPNPTSTRTRTPVAHTNSATSS----RPPPPFTTHSPPTGSSPFSSTGPMTAT 1594

Query: 440  ETVSRSVAPMRGGEITAHWLLTNSTTSADVTGSSASYPEGVNASVLTQFSDSTVQSGGSH 499
               + +  P      T         +++ VT S+ +     +A + T  S  ++ +G   
Sbjct: 1595 SFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSMPTG--- 1651

Query: 500  TALGDRSYSESSSTSSSESLNSSAPRGERSIAGISYGQVRGTAIEQRTSSDH------TD 553
            T     +   + ST ++ ++  +     ++++ ++  +   T++   TSS H      T 
Sbjct: 1652 TIPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKT-STSLHSHTSSTHHAEATSTS 1710

Query: 554  HTYLSSTFTKGERALLSITDNSSSSDIVESSTSYIKISNSSHSEYSSFFHAQTERSNISS 613
             T ++   T      +++T + +S     SS S  K S S HS  SS  H +   ++ +S
Sbjct: 1711 TTNITPNPTSTGTPPMTVTTSGTSQS--RSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTS 1768

Query: 614  YDGEYAQPSTESPVLHT-----SNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSSSS 668
                +    T +PV HT     S LP+   T + P  +  + +     + S  ++++  +
Sbjct: 1769 ITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGPVTATSFQTTTTYPT 1828

Query: 669  SSSSGPPLP--LPSVSQSHHLFSS---ILPS-----TRASVHLLKS-------------- 704
             S     LP  +PS S S    S+   I+P+     T AS+H + +              
Sbjct: 1829 PSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGTIPPPTTIKATGS 1888

Query: 705  --TSDASTPWSSSPSPLPVSLTT---STSAPLSVSQTTLPQ---SSSTPVLPR----ARE 752
              T+   TP +S  S  P S +T   STS P   S T  P+   +S+T + P+       
Sbjct: 1889 THTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVTPTSTTNITPKHTSTGTR 1948

Query: 753  TPV---TSFQTSTM-TSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKA 808
            TPV   TS  +S + T F T  HS  T      ST      +T +   +  + PT S   
Sbjct: 1949 TPVAHTTSASSSRLPTPFTT--HSPPTGSSPFSSTGP----MTATSFQTTTTYPTPSHPQ 2002

Query: 809  VTTNSPLPPSLTESSTEQTLPATSTNLAQMSPTFTTTILKTSQPLMTTPGTLSSTASLVT 868
             T  + +PP  T   T  T     T   QM+ +   +I  T    +  P TL +T S  T
Sbjct: 2003 TTLPTHVPPFSTSLVTPSTHTVIITTHTQMATS--ASIHSTPTGTVPPPTTLKATGSTHT 2060

Query: 869  GPIAVQTTAGKQLSLTHPEILVPQISTEGGISTERNRVIVDATTGLIPLTSVPTSAKEMT 928
             P    TT+G   S TH        S+    S+        +     P+T+        T
Sbjct: 2061 APPMTVTTSGT--SQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSAT 2118

Query: 929  TKLGVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSATFAVQSSTQSPTTVSSSASVNS 988
            T +  T + S +      SPSP           AP + +  V SS  SP T S S   +S
Sbjct: 2119 TPVSTTNQLSSSF-----SPSPS----------APSTVSSYVPSSHSSPQTSSPSVGTSS 2163

Query: 989  CAVNPCLHN 997
              V+  +H+
Sbjct: 2164 SFVSAPVHS 2172



 Score = 94.0 bits (232), Expect = 9e-19
 Identities = 246/1076 (22%), Positives = 383/1076 (35%), Gaps = 176/1076 (16%)

Query: 26   AAPGTRDPPPSPARRALSLAPLAGAGLELQLERRPEREPPPTP----------PRERRGP 75
            A+P T     S  R  ++L   A +G    L +   +E P T           P    GP
Sbjct: 1313 ASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTGP 1372

Query: 76   ATPGPS------------------YRAPEPGAATQRGPSGRAP--RGGSADAAWKH---- 111
             TP P                   Y  P+    T   P+  +P    G   A   H    
Sbjct: 1373 TTPQPGQPTRPTATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTT 1432

Query: 112  -----WPESNTEAHVENITFYQNQEDFSTVSSKEGVMVQTSGKSHAASDAPENLTLLAET 166
                  PE+    HV   +         TV +     + TS  +H+A   P        T
Sbjct: 1433 YPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASNHSA---PTGTIPPPTT 1489

Query: 167  ADARGRSGSSSRTNFTILPVGYSLEIATALTSQSGNLASESLHLPSSSSEFDERIAAFQT 226
              A G    S+ T   I P   +   + A +S S N    SLH  +SS+   E +    T
Sbjct: 1490 LKATG----STHTAPPITPT--TSGTSQAHSSFSTNKTPTSLHSHTSSTHHPE-VTPTST 1542

Query: 227  KSGTASEMGTERAMGLSEEWTVHSQEATTSAWSPSFL---------PALEMGELTTPSRK 277
             + T +   T     ++     H+  AT+S   P F          P    G +T  S K
Sbjct: 1543 TTITPNPTSTRTRTPVA-----HTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFK 1597

Query: 278  RNSSGPDLSWLHFYRTAASS-PLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATV-- 334
              ++ P  S  H   T  +  P    S  + ST  +   T  Q ++ +   +M   T+  
Sbjct: 1598 TTTTYPTPS--HPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSMPTGTIPP 1655

Query: 335  ----FTDGGPRTLRSLTVSLGPVSKTEGFPKDSRIATTSSSVLLSPSAVESRRNS--RVT 388
                   G   T  ++T++    S+       ++ +T+  S   S    E+   S   +T
Sbjct: 1656 PTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNIT 1715

Query: 389  GNPGDEEFIEPSTENEFGLTSLR--WQNDSPTFGEHQLASSS---EVQNGSPMSQT--ET 441
             NP       P T    G +  R  +     +   H   SS+   EV + S  S T   T
Sbjct: 1716 PNPTSTG-TPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHT 1774

Query: 442  VSRSVAPM-RGGEITAHWLLTNSTTSADVTGSSASYPEGVNASVLTQFSDSTVQSGGSHT 500
             + +  P+      T+  L T  TT +  TG++     G   +   Q + +       HT
Sbjct: 1775 STGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGPVTATSFQTTTTYPTPSHPHT 1834

Query: 501  ALGDRSYSESSSTSSSESLNSSAPRGERSIAGISYGQVRGTAIEQRTSSDHTDHTYLSST 560
             L     S S+S  +  +     P   +     S   +    I   T+   T  T+ +  
Sbjct: 1835 TLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGTIPPPTTIKATGSTHTAPP 1894

Query: 561  FTKGERALLSITDNSSSSDIVESSTSYIKISNSSHSEYSSFFHAQTERSNISSYDGEYAQ 620
             T         T  +S S    SS S  K S S     SS  H +   ++ ++   ++  
Sbjct: 1895 MTP-------TTSGTSQSP---SSFSTAKTSTSLPYHTSSTHHPEVTPTSTTNITPKHTS 1944

Query: 621  PSTESPVLHTSNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPS 680
              T +PV HT++  S    +  P T+    T +   S +   +++S  ++++ P    P 
Sbjct: 1945 TGTRTPVAHTTSASS--SRLPTPFTTHSPPTGSSPFSSTGPMTATSFQTTTTYPTPSHPQ 2002

Query: 681  VSQSHHL----FSSILPSTRASV-----HLLKSTSDASTPWSSSPSPLPVSLT--TSTSA 729
             +   H+     S + PST   +      +  S S  STP  + P P  +  T  T T+ 
Sbjct: 2003 TTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAP 2062

Query: 730  PLSV-----------------------SQTTLPQSSST--PVLPRARETPVTSFQT---- 760
            P++V                       S + LPQ+SS+  P  P   + P  S  T    
Sbjct: 2063 PMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVS 2122

Query: 761  ----------------STMTSFMTMLHSSQTADLKSQSTPHQ----EKVITESKSPSLVS 800
                            ST++S++   HSS      S  T           T   S S  S
Sbjct: 2123 TTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSS 2182

Query: 801  LPTESTKAVTTNSPLPPSLTESST--EQTLPATSTN---LAQMSPTFTTTILKT-----S 850
            L T  T A  + SPL PS   +ST    TLP T ++   L+ + P  T T+  T     +
Sbjct: 2183 LSTHPTTASVSASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLA 2242

Query: 851  QPLMTTPGTLSSTASLVTGP-IAVQTTAGKQLSLTHPEILVPQISTEGGISTERNRVIVD 909
               +  P T  +TAS  T P  + Q+T  +  SLT        +S   G++      + +
Sbjct: 2243 SSTIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIPTSPVTN 2302

Query: 910  ATT-----GLIPLTSVPTSAKEMTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAED 960
             TT      L P T   TS+    T  G T   +P S SLGT P+P +  V +  +
Sbjct: 2303 LTTRHPGPTLSPTTRFLTSS---LTAHGSTPASAPVS-SLGT-PTPTSPGVCSVRE 2353



 Score = 37.0 bits (84), Expect = 0.13
 Identities = 46/179 (25%), Positives = 64/179 (35%), Gaps = 29/179 (16%)

Query: 815  LPPSLTESSTEQTLPATSTNLAQMSPTFTTTILKTSQPLMTTPGTLSSTASLVTGPIAVQ 874
            +PP+  +  T   LP T +   Q+ P   T+         TT G LSST      P +  
Sbjct: 1197 MPPTTPQPPTTPQLPTTGSRPTQVWPMTGTS---------TTIGLLSSTG---PSPSSNH 1244

Query: 875  TTAGKQLSLTHPEILVPQISTEGGISTER--NRVIVDATTGLIP------------LTSV 920
            T A    +   P  L     T       R    V   AT+GL P            +T  
Sbjct: 1245 TPASPTQTPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQA 1304

Query: 921  PTSAKEMTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSATFAVQSSTQSPTT 979
             T A   T     T+     +R+  T P+P T+  S      PKS    +  +T + TT
Sbjct: 1305 TTRATASTASPATTSTAQSTTRTTMTLPTPATSGTSPT---LPKSTNQELPGTTATQTT 1360


>gi|89026265 PREDICTED: mucin 12 [Homo sapiens]
          Length = 978

 Score = 97.1 bits (240), Expect = 1e-19
 Identities = 159/630 (25%), Positives = 242/630 (38%), Gaps = 88/630 (13%)

Query: 463  STTSADVTGSSASYPEGVNASVLTQFSDSTVQSG------GSHTALG--DRSYSESSSTS 514
            STTS+ V+  S +      ++  T F  ST   G       SH++ G  D + S  S+T+
Sbjct: 45   STTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTA 104

Query: 515  SSESLNS----SAPRGERSIAGISYGQVRG-----TAIEQRTSSDHTDHTYLSSTFTKGE 565
            SS    S    S P    +          G     T +   T S HT  +   ST  +GE
Sbjct: 105  SSLGPESTTFHSGPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGE 164

Query: 566  RALLSITDNSSSSDIVESSTS--YIKISNSSHSEYSSFFHAQTERSNISSYDGEYAQPST 623
                    NS  +     +T+  ++++S +SH   SS     T  ++ S+      + S 
Sbjct: 165  STTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSS-----TPTTHFSASSTTLGR-SE 218

Query: 624  ESPVLHTSNLPSYT-PTINMPNTSVVLDTDAEFVSDSSSSSSS---SSSSSSSGPPLPLP 679
            ES  +H+S + + T P+     TS +++    + S   S+ +     SS++S        
Sbjct: 219  ESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRT 278

Query: 680  SVSQSHHLFSSILPSTRASVHLLKSTSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLP 739
            S S + H  SS  P +  S  + + TS  S+P S + +  P S TTS  +  S +  + P
Sbjct: 279  SHSSTTHTISS--PPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSP 336

Query: 740  QSSSTPVLPR-----ARETPVTSFQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESK 794
             ++    LP       R    T+F  S  +   T+  ++ T  L ++ST     + + S+
Sbjct: 337  DTNGITPLPAHFTTSGRIAESTTFYISPGSMETTLASTTTTPGLSAKSTI----LYSSSR 392

Query: 795  SPSLVSLPTESTKAVTTNSPLPP-SLTESSTEQTLPATSTN--LAQMSPTFTTTILKTSQ 851
            SP     P   T +  +  P    S  ES+     PA++T   L+Q S TF +    T  
Sbjct: 393  SPDQTLSPASMTSSSISGEPTSLYSQAESTHTTAFPASTTTSGLSQESTTFHSKPGSTET 452

Query: 852  PLMTTPGTLSSTASLVTGPIAVQTTAGKQLSLTHP-EILVPQISTEGGI------STERN 904
             L     T SS A   T P    +  G  LS   P    VP +S E         STE  
Sbjct: 453  TLSPGSITTSSFAQEFTTP---HSQPGSALSTVSPASTTVPGLSEESTTFYSSPGSTETT 509

Query: 905  RVIVDATTGLIPLTSVP-----------TSAKEMTTKLGV-TAEYSPASRSLGTSPSPQT 952
                  T  +    S P             A   TT +G  +  +  +S + GT+P P  
Sbjct: 510  AFSHSNTMSIHSQQSTPFPDSPGFTHTVLPATLTTTDIGQESTAFHSSSDATGTTPLPAR 569

Query: 953  TVVSTAEDLAPKSATFAVQSS----------------TQSPTTVSSSASVNSCAVNP--- 993
               STA DL  +  TF +  S                T+  TT  +S S  S  V+    
Sbjct: 570  ---STASDLVGEPTTFYISPSPTYTTLFPASSSTSGLTEESTTFHTSPSFTSTIVSTESL 626

Query: 994  -CLHNGECVADNTSRGYHCRCPPSWQGDDC 1022
              L  G C       G  C CP  + G  C
Sbjct: 627  ETLAPGLCQEGQIWNGKQCVCPQGYVGYQC 656



 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 100/409 (24%), Positives = 152/409 (37%), Gaps = 55/409 (13%)

Query: 630  TSNLPSYTPTINMPNTSVVL-------DTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVS 682
            T+ LP  T T  +   S          DT     S +SS  S  S++S S P     S  
Sbjct: 11   TTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPG----STH 66

Query: 683  QSHHLFSSILPSTRASVHLLKSTSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQSS 742
             +    S+ +P         +ST+  S+P S+  +  P S T S+  P S +  + P S+
Sbjct: 67   TTAFPGSTTMPGVSQ-----ESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSGPGST 121

Query: 743  STPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLP 802
             T +LP   +    S      T   +   S  T    + ST  Q +  T    P+  S  
Sbjct: 122  ETTLLP---DNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPN--SKD 176

Query: 803  TESTKAVTTNSPLPPSLTESSTEQTLP-----ATSTNLAQMSPTFTTTILKTSQPLMTTP 857
            T      TT++ +  S T   +  + P     A+ST L +     +TT+  +     TTP
Sbjct: 177  TTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEE--STTVHSSPVATATTP 234

Query: 858  GTLSSTAS-LVTGPIAVQTTAGKQLSLTHPEILVPQISTEGGISTERNRVIVDATTGLI- 915
                ST S LV    A  ++ G   ++  PE      ST  G S E +R    +TT  I 
Sbjct: 235  SPARSTTSGLVEESTAYHSSPGSTQTMHFPE-----SSTASGRS-EESRTSHSSTTHTIS 288

Query: 916  -------PLTSVPTSAKEMTTKLGVT--AEYSPAS----RSLGTSPSPQTTVVS------ 956
                    L   PTS       +  T   E S  S     S  +  SP T  ++      
Sbjct: 289  SPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHF 348

Query: 957  TAEDLAPKSATFAVQSSTQSPTTVSSSASVNSCAVNPCLHNGECVADNT 1005
            T      +S TF +   +   T  S++ +    A +  L++     D T
Sbjct: 349  TTSGRIAESTTFYISPGSMETTLASTTTTPGLSAKSTILYSSSRSPDQT 397



 Score = 45.1 bits (105), Expect = 5e-04
 Identities = 79/306 (25%), Positives = 117/306 (38%), Gaps = 33/306 (10%)

Query: 704 STSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQSS--------STPVLPRARETPV 755
           ST   + P S++ + L    TT  S+P S   T  P S+        ST    R   T  
Sbjct: 8   STETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHT 67

Query: 756 TSFQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTEST-----KAVT 810
           T+F  ST     TM   SQ +   S S+P          S +  SL  EST        T
Sbjct: 68  TAFPGST-----TMPGVSQES-TASHSSPGSTDTTLSPGSTTASSLGPESTTFHSGPGST 121

Query: 811 TNSPLPPSLTESS-TEQTLP---ATSTNLAQMSPTFTTTILKTSQPLMTTPGTLSSTASL 866
             + LP + T S   E + P   +T +    +SP  +TT    S    + P +  +T + 
Sbjct: 122 ETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAP 181

Query: 867 VTGPIAVQTTAGKQLSLT-HPEILVPQISTEGGISTERNRVIVDATTGLIPLTSVPTSAK 925
            T      T+A  +LS T H        +     ST   R     T    P+ +  T + 
Sbjct: 182 PT-----TTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSP 236

Query: 926 EMTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSATFAVQSSTQSPTTVSSSAS 985
             +T  G+  E +    S G++ +      STA   + +S T    S + +  T+SS  S
Sbjct: 237 ARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRT----SHSSTTHTISSPPS 292

Query: 986 VNSCAV 991
             S  V
Sbjct: 293 TTSALV 298



 Score = 31.2 bits (69), Expect = 7.2
 Identities = 63/322 (19%), Positives = 114/322 (35%), Gaps = 58/322 (18%)

Query: 67  TPPRERRGPATPGPSYRAPEPGAATQRGPSGRAPRGGSADAAWKHW-PESN----TEAH- 120
           +PP           SY +     AT   P      G S ++   H  P++N      AH 
Sbjct: 289 SPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHF 348

Query: 121 ------VENITFYQNQEDFSTVS---------SKEGVMVQTSGKSHAASDAPENLTLLAE 165
                  E+ TFY +     T           S +  ++ +S +S   + +P ++T  + 
Sbjct: 349 TTSGRIAESTTFYISPGSMETTLASTTTTPGLSAKSTILYSSSRSPDQTLSPASMTSSSI 408

Query: 166 TADARGRSGSSSRTNFTILPV-----GYSLEIATALTSQSGNLASESLHLPSSSSEFDER 220
           + +       +  T+ T  P      G S E +T   S+ G+  +       ++S F + 
Sbjct: 409 SGEPTSLYSQAESTHTTAFPASTTTSGLSQE-STTFHSKPGSTETTLSPGSITTSSFAQE 467

Query: 221 IAAFQTKSGTASEM---GTERAMGLSEEWT---------------------VHSQEATTS 256
                ++ G+A       +    GLSEE T                     +HSQ++T  
Sbjct: 468 FTTPHSQPGSALSTVSPASTTVPGLSEESTTFYSSPGSTETTAFSHSNTMSIHSQQSTPF 527

Query: 257 AWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASSPLLDLSSSSESTEKLNNST 316
             SP F   +    LTT    + S+        F+ ++ ++    L + S +++ +   T
Sbjct: 528 PDSPGFTHTVLPATLTTTDIGQESTA-------FHSSSDATGTTPLPARSTASDLVGEPT 580

Query: 317 GLQSSSVSQTKTMHVATVFTDG 338
               S      T+  A+  T G
Sbjct: 581 TFYISPSPTYTTLFPASSSTSG 602


>gi|167736355 mucin 4 isoform a [Homo sapiens]
          Length = 5284

 Score = 95.9 bits (237), Expect = 2e-19
 Identities = 222/951 (23%), Positives = 368/951 (38%), Gaps = 118/951 (12%)

Query: 132  DFSTVSSKEGVMVQTSGKSHAASDAPENLTLLAETADARGRSGSSSRTNFTILPVGYSLE 191
            D S++S+     +  +  S A++     L +   ++ + G +     T+ +    G++  
Sbjct: 2885 DTSSISTGHATPLHVTSPSSASTGHATPLPVTDTSSASTGHANPLHVTSPSSASTGHATP 2944

Query: 192  IATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTASEMGTERAMGLSEEWTVHSQ 251
            +    TS +    +  L + S SS            S +++  G    + +++  +  + 
Sbjct: 2945 LPVTDTSSASTGHATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHTTPLPVTDTSSASTG 3004

Query: 252  EAT----TSAWSPSFLPALEMGELTTPSRKRNSSGP-DLSWLHFYRTAASSPLLDLSSSS 306
            +AT    TS  S S      +    T S     + P  ++ L    T  ++PL   S SS
Sbjct: 3005 QATALPVTSTSSASTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSS 3064

Query: 307  ESTEKLNNS--TGLQSSSVSQTKTMHVATVFT-DGGPRTLRSLTVSLGPVSKTEGFPKDS 363
             ST        T   S+S  Q   + V ++ +   G  T   +T    P S + G     
Sbjct: 3065 ASTGHATPLLVTDASSASTGQATPLPVTSLSSVSTGDTTPLPVT---SPSSASTGHATSL 3121

Query: 364  RIATTSSSVLLSPSAVE-SRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQNDSPTFGEH 422
             +  TSS+     +++  +  +S  TG+       + S+ +    T L     S     H
Sbjct: 3122 PVTDTSSASTGDTTSLPVTDTSSAYTGDTTSLPVTDTSSSSTGDTTPLLVTETSSVSTGH 3181

Query: 423  QL------ASSSEVQNGSPMSQTETVSRSVAPMRGGEIT-AHWLLTNSTTSADVTG-SSA 474
                    ASS+   + +P+  T   S S        +T    + T   T   VTG SSA
Sbjct: 3182 ATPLLVTDASSASTGHATPLHVTSPSSASTGDTTPVPVTDTSSVSTGHATPLPVTGLSSA 3241

Query: 475  SYPEGVNASVLTQFSDSTVQS------GGSHTALGDRSYSESSSTSSSESLNSSAPRGER 528
            S  +     V    S ST Q+        S  + GD      +S SS+ S   + P    
Sbjct: 3242 STGDTTRLPVTDISSASTGQATPLPVTNTSSVSTGDTMPLPVTSPSSA-STGHATPLPVT 3300

Query: 529  SIAGISYGQVRGTAIEQRTSSDHTDHTYL-----SSTFTKGERALLSITDNSSSSDIVES 583
            S +  S G      +   TSS  T HT       +S+ + G+   L +T  SS+S    +
Sbjct: 3301 STSSASTGHATPVPVTS-TSSASTGHTTPLPVTDTSSASTGDTTPLPVTSPSSAST-GHT 3358

Query: 584  STSYIKISNSSHSEYSSFFHAQTERSNISSYDGEYAQPSTESPVLHTSNLPSYTPTINMP 643
            +  ++ I +S+ +         T    ++         +T  PV  TS++ +   T  +P
Sbjct: 3359 TPLHVTIPSSAST-------GDTSTLPVTGASSASTGHATPLPVTDTSSVSTGHAT-PLP 3410

Query: 644  NTSVVL----DTDAEFVSDSSSSSS--------SSSSSSSSGPPLPL-----PSVSQSHH 686
             TS+      DT    V+D+SS+S+        +S SS S+G   PL      SVS  H 
Sbjct: 3411 VTSLSSVSTGDTTPLPVTDASSASTGQATPLPVTSLSSVSTGDTTPLLVTDASSVSTGH- 3469

Query: 687  LFSSILPSTRASVHLLKSTS-----DASTPWSSSPSPLPV----SLTTSTSAPLSVSQ-T 736
              ++ LP T  S      T+     D S+  +   +PLPV    S++T  + PL V+  +
Sbjct: 3470 --ATPLPVTDTSSASTGDTTRLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLLVTDAS 3527

Query: 737  TLPQSSSTPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADLKS-QSTPHQEKVITESKS 795
            ++    +TP+       PVT   +S  T   T L  + T+   + Q+TP    + + S S
Sbjct: 3528 SVSTGHATPL-------PVTD-TSSASTGDTTRLPVTDTSSASTGQATPLPVTIPSSSSS 3579

Query: 796  PSLVSLPTESTKAVTTNSPLPPSLTESSTEQT-----LPATSTNLAQM---SPTFTTTIL 847
                 LP  ST +V+T    P  +T  S+  T     LP TST+ A     +P   T   
Sbjct: 3580 GHTTPLPVTSTSSVSTGHVTPLHVTSPSSASTGHVTPLPVTSTSSASTGHATPLLVTDAS 3639

Query: 848  KTSQ----PLMTTPGTLSSTASLVTGPIAVQTTAGKQLSLTHPEILVPQISTEGGISTER 903
              S     PL  T  + +ST      P+   ++A    +   P   +  +ST        
Sbjct: 3640 SVSTGHATPLPVTDASSASTGDTTPLPVTDTSSASTGQATPLPVTSLSSVST-------- 3691

Query: 904  NRVIVDATTGLIPLTSVPTSAKEMTTKLGVTAEYSPASRSLG-------TSPSPQTTVVS 956
                    T  +P+T   +++    T L VT    P+S S G       TSPS  +T  +
Sbjct: 3692 ------GDTTPLPVTDASSASTGHATPLPVTI---PSSVSTGDTMPLPVTSPSSASTGHA 3742

Query: 957  TAEDLAPKSATFAVQSSTQSPTTVSSSASVNSCAVNPCLHNGECVADNTSR 1007
            T   +   S+  +   +T  P T +SSAS       P         D+T+R
Sbjct: 3743 TPLPVTGLSSA-STGDTTPLPVTDTSSASTRHATPLPVTDTSSASTDDTTR 3792



 Score = 95.1 bits (235), Expect = 4e-19
 Identities = 232/956 (24%), Positives = 366/956 (38%), Gaps = 154/956 (16%)

Query: 134  STVSSKEGVMVQTSGKSHAASDAP-------ENLTLLAETADARGRSGSSSRTNFTILPV 186
            +T S  EG+   TSG++   S  P       ++ T L   + + G    S+    +I+P 
Sbjct: 813  TTPSGSEGI--STSGETTRFSSNPSRDSHTTQSTTELLSASASHGAIPVSTGMASSIVPG 870

Query: 187  GYSLEIATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTASEMGTERAMGLSEEW 246
             +   ++ A T+  G    +S   P+S S   +  AA    S  A    T  + G S+  
Sbjct: 871  TFHPTLSEASTA--GRPTGQSS--PTSPSASPQETAAI---SRMAQTQRTRTSRG-SDTI 922

Query: 247  TVHSQEATTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASSPLLDLSSSS 306
            ++ SQ   T +  P   P++    LT+P  + ++  P  S   F  TA  S    L  + 
Sbjct: 923  SLASQATDTFSTVPPTPPSITSTGLTSPQTETHTLSPSGSGKTF-TTALISNATPLPVTY 981

Query: 307  ESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVSKTEGFPKDSRIA 366
             S+    ++T L  +  S   T H AT      P ++ +   +  PV+ T          
Sbjct: 982  ASSASTGHTTPLHVTDASSVSTGH-ATPLPVTSPSSVSTGHTTPLPVTDT---------- 1030

Query: 367  TTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQNDSPTFGEHQLAS 426
            ++ S+  ++P  V S  +S  TG+       + S+ +   +T L   +           S
Sbjct: 1031 SSESTGHVTPLPVTSF-SSASTGDSTPLPVTDTSSASTGHVTPLPVTS----------LS 1079

Query: 427  SSEVQNGSPMSQTETVSRSVAPMRGGEIT-------AHWL-LTNSTTSADVTGSSASYPE 478
            S+   + +P+  T+T S S        +T        H   L  + TS+  TG + S P 
Sbjct: 1080 SASTGDTTPLPVTDTSSASTGHATSLPVTDTSSVSTGHTTPLPVTDTSSASTGHATSLPV 1139

Query: 479  GVNASVLT------QFSDSTVQSGGSHTALGDRSYSESSS---------TSSSESLNSSA 523
               +SV T        +D++  S G  T L   S S  S+         + SS S   + 
Sbjct: 1140 TDTSSVSTGHTTPLHVTDASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHAT 1199

Query: 524  PRGERSIAGISYGQVRGTAIEQRTSSDHTDHTY-----LSSTFTKGERALLSITDNSSSS 578
            P      +  S G      +    SS  TDH       + S  + G    L +TD SS+S
Sbjct: 1200 PLLVTDTSSASTGHATPLPVTD-ASSVSTDHATSLPVTIPSAASTGHTTPLPVTDTSSAS 1258

Query: 579  DIVESSTSYIKISNSSHSEYSSFFHAQTERSNISSYDGEYAQPSTESPVLHTSNLPSYTP 638
                 +TS +    SS S   +     T  S+ S+  G        SP   ++   +  P
Sbjct: 1259 --TGQATSLLVTDTSSVSTGDTTPLPVTSTSSAST--GHVTPLHVTSPSSASTGHATPLP 1314

Query: 639  TINMPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLP-----SVSQSH----HLFS 689
              ++ + S           D+     +S SS+S+G   PLP     SVS  H    H+  
Sbjct: 1315 VTSLSSAST---------GDTMPLPVTSPSSASTGDTTPLPVTDASSVSTGHTTPLHVTD 1365

Query: 690  SILPSTRASVHL-LKSTSDASTPWSSSPSPLPVSLTTSTSA------PLSVSQTTLPQSS 742
            +   ST  +  L + S S  ST      +PLPV  T+ +SA      PL V+ T+   + 
Sbjct: 1366 ASSASTGQATPLPVTSLSSVST---GDTTPLPV--TSPSSASTGHATPLLVTDTSSASTG 1420

Query: 743  STPVLPRARETPVTSFQTSTMTSFMTMLHSSQT---------ADLKSQSTPHQEK-VITE 792
                LP    T  +S  T   TS    + S+ +          D  S ST      ++T+
Sbjct: 1421 HATPLP---VTDASSVSTDHATSLPVTIPSAASTGHTTPLPVTDTSSASTGQATSLLVTD 1477

Query: 793  SKSPS---LVSLPTESTKAVTTNSPLPPSLTESSTEQT-----LPATSTNLAQMSPTFTT 844
            + S S      LP  ST + +T    P  +T  S+  T     LP TS + A    T   
Sbjct: 1478 TSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSASTGHATPLPVTSLSSASTGDTMPL 1537

Query: 845  TILKTSQPLM--TTPGTLSSTASLVTG---PIAVQTTAGKQLSLTHPEILVPQISTEGGI 899
             +   S      TTP  ++  +S+ TG   P+ V + +      T P  +    S   G 
Sbjct: 1538 PVTSPSSASTGDTTPLPVTDASSVSTGHTTPLPVTSPSSASTGHTTPLPVTDTSSASKGD 1597

Query: 900  STERNRVIVDATTGLIPLTSVPTSAKEMTTKLGVTAEYSPASRSLG-TSPSPQTTVVSTA 958
            +T             +P+TS  +++   TT L VT     +S S G T+P P T   S +
Sbjct: 1598 TTP------------LPVTSPSSASTGHTTPLPVT---DTSSASTGDTTPLPVTNASSLS 1642

Query: 959  EDLA-------PKSATFAVQSSTQSPTTVSSSASVNSCAVNPCLHNGECVADNTSR 1007
               A       P SA  +   +T  P T +SSAS       P         D+T+R
Sbjct: 1643 TGHATPLHVTSPSSA--STGHATPLPVTSTSSASTGHATPLPVTGLSSATTDDTTR 1696



 Score = 95.1 bits (235), Expect = 4e-19
 Identities = 233/1012 (23%), Positives = 388/1012 (38%), Gaps = 146/1012 (14%)

Query: 134  STVSSKEGVMVQTSGKSHAASDAPENLTLLAETADARGRSGSSSRTNFTILPVGYSLEIA 193
            S+VS+ +   +  +  S A++     L +   ++ + G +     T+ +    G +  + 
Sbjct: 2279 SSVSTGDTTPLPVTSPSSASTGHATPLHVTDASSASTGHATPLPVTSLSSASTGDTTPLP 2338

Query: 194  TALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTASEMGTERAMGLSEEWTVHSQEA 253
                S +    +  LH+  +SS            S +++  G    + +++  +  + + 
Sbjct: 2339 VTSPSSASTGHATPLHVTDASSVSTGDTTPLPVTSSSSASSGHTTPLPVTDASSASTGDT 2398

Query: 254  T------TSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASSPLLDLSSSSE 307
            T      TS+ S      L +  L++ S    +  P ++ +    T  ++PL   S+SS 
Sbjct: 2399 TPLPVTDTSSASTGHATHLPVTGLSSASTGDTTRLP-VTNVSSASTGHATPLPVTSTSSA 2457

Query: 308  STEKLNNSTGLQSSSVSQTKTMHV----ATVFTDGGPRTLRSLTVSLGPVSKTEGFP-KD 362
            ST       G  +SSVS   T  +    A+  + G    L   + S      T   P  D
Sbjct: 2458 STGDTTPLPGTDTSSVSTGHTTPLLVTDASSVSTGDTTRLPVTSPSSASTGHTTPLPVTD 2517

Query: 363  SRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQNDSPTFGEH 422
            +  A+T  +  L  +   S      T          PS+ +    TSL   + S     H
Sbjct: 2518 TPSASTGDTTPLPVTNASSLSTRHATSL----HVTSPSSASTGHATSLPVTDTSAASTGH 2573

Query: 423  QL------ASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADVTGSSASY 476
                     SS+   + +P+  T+T S S      G+ T    L  + TS+  TG +   
Sbjct: 2574 ATPLPVTSTSSASTGDTTPLPVTDTYSAST-----GQATP---LPVTDTSSASTGDTTPL 2625

Query: 477  PEGVNASVLTQFSDSTVQSGGSHTALGDRSYSESSSTSSSESLNSSAPRGERSIAGISYG 536
            P    +S  T  +     +  S  + G  +    +S SS+ S   + P      + +S G
Sbjct: 2626 PVTDTSSASTGHATPLPVTNTSSVSTGHATPLHVTSPSSA-STGHTTPLPVTDASSVSTG 2684

Query: 537  QVRGTAIEQRTSSDHTDHTY-----LSSTFTKGERALLSITDNSSSS----------DIV 581
                  +    SS  T H       + S+ + G    L +TD SS S          D  
Sbjct: 2685 HATSLPVTD-ASSVFTGHATSLPVTIPSSASSGHTTPLPVTDASSVSTGHATSLPVTDAS 2743

Query: 582  ESSTSYIKISNSSHSEYSSFFHAQ----TERSNISSYDGEYAQPSTESPVLHTSNLPSYT 637
              ST +      + +   S  HA     T  S++S+ D      +T  PV  TS+  +  
Sbjct: 2744 SVSTGHATPLPVTDASSVSTGHATPLPLTSLSSVSTGD------TTPLPVTDTSSASTGQ 2797

Query: 638  PTINMPNTSVVL----DTDAEFVSDSSSSSS--------SSSSSSSSGPPLPLP-----S 680
             T  +P TS+      DT    V+D+SS+S+        + +SS+S+G   PLP     S
Sbjct: 2798 AT-PLPVTSLSSVSTGDTTPLPVTDTSSASTGHATSLPVTDTSSASTGHATPLPDTDTSS 2856

Query: 681  VSQSHHLFSSILPSTRASVHLLKS--TSDASTPWSSSPSPL----PVSLTTSTSAPLSVS 734
             S  H     +  ++ AS+    S   +D S+  +   +PL    P S +T  + PL V+
Sbjct: 2857 ASTGHATLLPVTDTSSASIGHATSLPVTDTSSISTGHATPLHVTSPSSASTGHATPLPVT 2916

Query: 735  QT-------------TLPQSSSTPVLPRARETPVTSFQTSTMTSF-MTMLHSSQTADL-- 778
             T             T P S+ST        T  +S  T   T   +T L S  T D   
Sbjct: 2917 DTSSASTGHANPLHVTSPSSASTGHATPLPVTDTSSASTGHATPLPVTSLSSVSTGDTTP 2976

Query: 779  ------KSQSTPHQEKV-ITESKSPSL---VSLPTESTKAVTT--NSPLPPSLTES-STE 825
                   S ST H   + +T++ S S     +LP  ST + +T   +PLP + T S ST 
Sbjct: 2977 LPVTSPSSASTGHTTPLPVTDTSSASTGQATALPVTSTSSASTGDTTPLPVTDTSSASTG 3036

Query: 826  QTLPATSTNLAQMSPTFTTTILKTSQPLMTTPGTLSSTASLVTGPIAVQTTAGKQLSLTH 885
            Q  P   T+L+ +S T  TT L  + P   + G   +T  LVT   +  T     L +T 
Sbjct: 3037 QATPLPVTSLSSVS-TGDTTPLPVTSPSSASTG--HATPLLVTDASSASTGQATPLPVTS 3093

Query: 886  PEILVPQISTEGGISTERNRVIVDATTGLIPLTSVPTSAKEMTTKLGVTAEYSPASRSLG 945
                +  +ST                T  +P+TS  +++    T L VT   S ++    
Sbjct: 3094 ----LSSVST--------------GDTTPLPVTSPSSASTGHATSLPVTDTSSASTGDTT 3135

Query: 946  TSPSPQTTVVSTAEDLA-PKSATFAVQSSTQSPTTVSSSASVNSCAVNPCLHNGECVADN 1004
            + P   T+   T +  + P + T +  +   +P  V+ ++SV++    P L      A +
Sbjct: 3136 SLPVTDTSSAYTGDTTSLPVTDTSSSSTGDTTPLLVTETSSVSTGHATPLLVTD---ASS 3192

Query: 1005 TSRGY----HCRCPPSWQ-GDDCSVDVNECLS------NPCPSTAMCNNTQG 1045
             S G+    H   P S   GD   V V +  S       P P T + + + G
Sbjct: 3193 ASTGHATPLHVTSPSSASTGDTTPVPVTDTSSVSTGHATPLPVTGLSSASTG 3244



 Score = 93.6 bits (231), Expect = 1e-18
 Identities = 237/1069 (22%), Positives = 405/1069 (37%), Gaps = 150/1069 (14%)

Query: 19   PLLLLPPAAPGTRDPPPSPARRALSLAPLAGAGLELQLERRPEREPPPTPPRERRGPATP 78
            PL +  P++  T    P P     S +   G    L +          T P     P++ 
Sbjct: 2928 PLHVTSPSSASTGHATPLPVTDTSSAS--TGHATPLPVTSLSSVSTGDTTPLPVTSPSSA 2985

Query: 79   GPSYRAPEPGAATQRGPSGRA---PRGGSADAAWKHW---PESNTEAHVENITFYQNQED 132
               +  P P   T    +G+A   P   ++ A+       P ++T +             
Sbjct: 2986 STGHTTPLPVTDTSSASTGQATALPVTSTSSASTGDTTPLPVTDTSSASTGQATPLPVTS 3045

Query: 133  FSTVSSKEGVMVQTSGKSHAASDAPENLTLLAETADARGRS--------GSSSRTNFTIL 184
             S+VS+ +   +  +  S A++     L +   ++ + G++         S S  + T L
Sbjct: 3046 LSSVSTGDTTPLPVTSPSSASTGHATPLLVTDASSASTGQATPLPVTSLSSVSTGDTTPL 3105

Query: 185  PV--------GYSLEIATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTASEMGT 236
            PV        G++  +    TS +    + SL +  +SS +     +      ++S  G 
Sbjct: 3106 PVTSPSSASTGHATSLPVTDTSSASTGDTTSLPVTDTSSAYTGDTTSLPVTDTSSSSTGD 3165

Query: 237  ERAMGLSEEWTVHSQEAT----TSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYR 292
               + ++E  +V +  AT    T A S S   A  +  +T+PS         +       
Sbjct: 3166 TTPLLVTETSSVSTGHATPLLVTDASSASTGHATPL-HVTSPSSASTGDTTPV------- 3217

Query: 293  TAASSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGP 352
                 P+ D SS S         TGL S+S   T  + V  + +    +       +   
Sbjct: 3218 -----PVTDTSSVSTGHATPLPVTGLSSASTGDTTRLPVTDISSASTGQATPLPVTNTSS 3272

Query: 353  VSKTEGFPKDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSLRW 412
            VS  +  P      +++S+   +P  V S  +S  TG+         S+ +    T L  
Sbjct: 3273 VSTGDTMPLPVTSPSSASTGHATPLPVTST-SSASTGHATPVPVTSTSSASTGHTTPLPV 3331

Query: 413  QNDSPTFGEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITA-HWLLTNSTTSADVTG 471
             +           SS+   + +P+  T   S S        +T      T  T++  VTG
Sbjct: 3332 TD----------TSSASTGDTTPLPVTSPSSASTGHTTPLHVTIPSSASTGDTSTLPVTG 3381

Query: 472  SSASYPEGVNASVLTQFSDSTVQSGGSHTALGDRSYSESSS---------TSSSESLNSS 522
            +S++         +T   D++  S G  T L   S S  S+          +SS S   +
Sbjct: 3382 ASSASTGHATPLPVT---DTSSVSTGHATPLPVTSLSSVSTGDTTPLPVTDASSASTGQA 3438

Query: 523  APRGERSIAGISYGQVRGTAIEQRTSSDHTDHTYLSSTFTK----GERALLSITDNSSSS 578
             P    S++ +S G      +   +S      T L  T T     G+   L +TD SS+S
Sbjct: 3439 TPLPVTSLSSVSTGDTTPLLVTDASSVSTGHATPLPVTDTSSASTGDTTRLPVTDTSSAS 3498

Query: 579  DIVESSTSYIKISNSSHSEYSSFFHAQTERSNISSYDGEYAQP-------------STES 625
                +      +S+ S  + +      T+ S++S+    +A P             +T  
Sbjct: 3499 TGQATPLPVTSLSSVSTGDTTPLL--VTDASSVST---GHATPLPVTDTSSASTGDTTRL 3553

Query: 626  PVLHTSNLPSYTPT---INMPNTSVVLDTDAEFVSDSSSSSS--------SSSSSSSSGP 674
            PV  TS+  +   T   + +P++S    T    V+ +SS S+        +S SS+S+G 
Sbjct: 3554 PVTDTSSASTGQATPLPVTIPSSSSSGHTTPLPVTSTSSVSTGHVTPLHVTSPSSASTGH 3613

Query: 675  PLPLPSVSQSHHLFSSILP---STRASVHLLKST----SDASTPWSSSPSPLPVSLTTST 727
              PLP  S S        P   +  +SV    +T    +DAS+  +   +PLPV+ T+S 
Sbjct: 3614 VTPLPVTSTSSASTGHATPLLVTDASSVSTGHATPLPVTDASSASTGDTTPLPVTDTSSA 3673

Query: 728  SA----PLSVSQTTLPQSSSTPVLP----------RARETPVTSFQTSTMTSFMTMLHSS 773
            S     PL V+  +   +  T  LP           A   PVT   + +    M +  +S
Sbjct: 3674 STGQATPLPVTSLSSVSTGDTTPLPVTDASSASTGHATPLPVTIPSSVSTGDTMPLPVTS 3733

Query: 774  QTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESSTEQT-----L 828
             ++     +TP     ++ + +     LP   T + +T    P  +T++S+  T     L
Sbjct: 3734 PSSASTGHATPLPVTGLSSASTGDTTPLPVTDTSSASTRHATPLPVTDTSSASTDDTTRL 3793

Query: 829  PAT-----STNLAQMSPTFTTTILKTSQPLMTTPGTLSSTASLVTG-PIAVQTTAGKQLS 882
            P T     ST  A   P  +T+   T     TTP  ++ T+S+ TG   ++  T+    S
Sbjct: 3794 PVTDVSSASTGHATPLPVTSTSSASTGD---TTPLPVTDTSSVSTGHATSLPVTSRSSAS 3850

Query: 883  LTHPEILVPQISTEGGISTERNRVIVDATTGLIPLTSVPTSAKEMTTKLGVTAEYSPASR 942
              H   L   ++    +ST        AT   +P+TS  + +    T L VT   SP+S 
Sbjct: 3851 TGHATPL--PVTDTSSVSTGH------ATP--LPVTSTSSVSTGHATPLPVT---SPSSA 3897

Query: 943  SLG-TSPSPQTTVVSTAE-DLAPKSATFAVQSST--QSPTTVSSSASVN 987
            S G  +P P T+  S +  D  P   T A   ST   +P  V+S +S +
Sbjct: 3898 STGHATPVPVTSTSSASTGDTTPLPVTNASSLSTGHATPLHVTSPSSAS 3946



 Score = 93.2 bits (230), Expect = 2e-18
 Identities = 207/949 (21%), Positives = 364/949 (38%), Gaps = 112/949 (11%)

Query: 134  STVSSKEGVMVQTSGKSHAASDAPENLTLLAETADARGRSGSSSRTNFTILPVGYSLEIA 193
            S+VS+ +   +  +  S A++    +L +   ++ + G +     T+ +    G++  + 
Sbjct: 2807 SSVSTGDTTPLPVTDTSSASTGHATSLPVTDTSSASTGHATPLPDTDTSSASTGHATLLP 2866

Query: 194  TALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTASEMGTERAMGLSEEWTVHSQEA 253
               TS +    + SL +  +SS            S +++  G    + +++  +  +  A
Sbjct: 2867 VTDTSSASIGHATSLPVTDTSSISTGHATPLHVTSPSSASTGHATPLPVTDTSSASTGHA 2926

Query: 254  T----TSAWSPSFLPALEMGELTTPSRKRNSSGP-DLSWLHFYRTAASSPLLDLSSSSES 308
                 TS  S S   A  +    T S     + P  ++ L    T  ++PL   S SS S
Sbjct: 2927 NPLHVTSPSSASTGHATPLPVTDTSSASTGHATPLPVTSLSSVSTGDTTPLPVTSPSSAS 2986

Query: 309  TEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVSKTEGFP-KDSRIAT 367
            T    ++T L  +  S   T         G    L   + S      T   P  D+  A+
Sbjct: 2987 T---GHTTPLPVTDTSSAST---------GQATALPVTSTSSASTGDTTPLPVTDTSSAS 3034

Query: 368  TSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQNDSPTFGEHQLASS 427
            T  +  L  +++ S      T  P       PS+ +    T L   +          ASS
Sbjct: 3035 TGQATPLPVTSLSSVSTGDTTPLP----VTSPSSASTGHATPLLVTD----------ASS 3080

Query: 428  SEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADVTGSSASYPEGVNASVLTQ 487
            +     +P+  T     S++ +  G+ T    L  ++ S+  TG + S P    +S  T 
Sbjct: 3081 ASTGQATPLPVT-----SLSSVSTGDTTP---LPVTSPSSASTGHATSLPVTDTSSASTG 3132

Query: 488  FSDSTVQSGGSHTALGDRSYSESSSTSSSESLNSSAPRGERSIAGISYGQVRGTAIEQRT 547
             + S   +  S    GD +    + TSSS S   + P      + +S G      +   +
Sbjct: 3133 DTTSLPVTDTSSAYTGDTTSLPVTDTSSS-STGDTTPLLVTETSSVSTGHATPLLVTDAS 3191

Query: 548  SSD--HTD--HTYLSSTFTKGERALLSITDNSSSSDIVESSTSYIKISNSSHSEYSSFFH 603
            S+   H    H    S+ + G+   + +TD SS S    +      +S++S  +      
Sbjct: 3192 SASTGHATPLHVTSPSSASTGDTTPVPVTDTSSVSTGHATPLPVTGLSSASTGD------ 3245

Query: 604  AQTERSNISSYDGEYAQPSTESPVLHTSNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSS 663
              T R  ++         +T  PV +TS++ S   T+ +P TS    +     +     +
Sbjct: 3246 --TTRLPVTDISSASTGQATPLPVTNTSSV-STGDTMPLPVTSPSSASTGH--ATPLPVT 3300

Query: 664  SSSSSSSSSGPPLPLPSVSQSHHLFSSILPSTRASVHLLKSTSDASTPWSSSPSPL--PV 721
            S+SS+S+    P+P+ S S +    ++ LP T         TS AST   ++P P+  P 
Sbjct: 3301 STSSASTGHATPVPVTSTSSASTGHTTPLPVT--------DTSSASTG-DTTPLPVTSPS 3351

Query: 722  SLTTSTSAPLSVSQTTLPQSSSTPVLP--------RARETPVTSFQTSTMTSF------M 767
            S +T  + PL V+  +   +  T  LP            TP+    TS++++       +
Sbjct: 3352 SASTGHTTPLHVTIPSSASTGDTSTLPVTGASSASTGHATPLPVTDTSSVSTGHATPLPV 3411

Query: 768  TMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESSTEQT 827
            T L S  T D    +TP      + + +     LP  S  +V+T    P  +T++S+  T
Sbjct: 3412 TSLSSVSTGD----TTPLPVTDASSASTGQATPLPVTSLSSVSTGDTTPLLVTDASSVST 3467

Query: 828  -----LPATSTNLAQMSPTFTTTILKTSQPL--MTTPGTLSSTASLVTGPIA-VQTTAGK 879
                 LP T T+ A    T    +  TS       TP  ++S +S+ TG    +  T   
Sbjct: 3468 GHATPLPVTDTSSASTGDTTRLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLLVTDAS 3527

Query: 880  QLSLTHPEILVPQISTEGGISTERNRVIVDATTGLIPLTSVPTSAKEMTTKLGVTAEYSP 939
             +S  H   L P   T    + +  R         +P+T   +++    T L VT   S 
Sbjct: 3528 SVSTGHATPL-PVTDTSSASTGDTTR---------LPVTDTSSASTGQATPLPVTIPSSS 3577

Query: 940  ASRSLGTSPSPQTTVVSTAEDLAPKSATFAVQSST--QSPTTVSSSASVNSCAVNPCLHN 997
            +S      P   T+ VST   + P   T    +ST   +P  V+S++S ++    P L  
Sbjct: 3578 SSGHTTPLPVTSTSSVSTGH-VTPLHVTSPSSASTGHVTPLPVTSTSSASTGHATPLLVT 3636

Query: 998  GECVADNTSRGYHCRCPPSWQGDDCSVDVNECLSNPCPSTAMCNNTQGS 1046
                A + S G+    P +   D  S    +    P   T+  +  Q +
Sbjct: 3637 D---ASSVSTGHATPLPVT---DASSASTGDTTPLPVTDTSSASTGQAT 3679



 Score = 91.7 bits (226), Expect = 4e-18
 Identities = 230/1035 (22%), Positives = 400/1035 (38%), Gaps = 130/1035 (12%)

Query: 18   LPLLLLPPAAPGTRDPPPSPARRALSLAPLAGAGLELQLERRPEREPPPTPPRERRGPAT 77
            +PL +  P++  T D  P P   A S++      L           P  +P     G  T
Sbjct: 1535 MPLPVTSPSSASTGDTTPLPVTDASSVSTGHTTPL-----------PVTSPSSASTGHTT 1583

Query: 78   PGPSYRAPEPGAATQRGPSGRAPRGGSADAAWKHW---PESNTEAHVENITFYQNQEDFS 134
            P P        ++  +G +   P    + A+  H    P ++T +     T      + S
Sbjct: 1584 PLPVTDT----SSASKGDTTPLPVTSPSSASTGHTTPLPVTDTSSASTGDTTPLPVTNAS 1639

Query: 135  TVSSKEGVMVQTSGKSHAASDAPENLTLLAETADARGRS------GSSSRT--NFTILPV 186
            ++S+     +  +  S A++     L + + ++ + G +      G SS T  + T LPV
Sbjct: 1640 SLSTGHATPLHVTSPSSASTGHATPLPVTSTSSASTGHATPLPVTGLSSATTDDTTRLPV 1699

Query: 187  GYSLEIATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKS-GTASEMGTERAMGLSEE 245
                ++++A T Q+  L   SL   S+       + +  + S G AS +    A   S  
Sbjct: 1700 ---TDVSSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHASPLLVTDASSASTG 1756

Query: 246  WTVHSQEATTSAWSPSFLPALEMGELTTPSRKRNSSGP--DLSWLHFYRTAASSPLLDLS 303
                     TS+ S +    L +  L++ S    +  P  D+S      +A++   + L 
Sbjct: 1757 QATPLPVTDTSSVSTAHATPLPVTGLSSASTDDTTRLPVTDVS------SASTGQAIPLP 1810

Query: 304  SSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVSKTEGFPKDS 363
             +S S+    ++T L  +  S   T          G  T   +T+   P S + G     
Sbjct: 1811 VTSPSSASTGDTTPLPVTDASSAST----------GDTTSLPVTI---PSSASSGHTTSL 1857

Query: 364  RIATTSS-SVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQNDSPTFGEH 422
             +   SS S   + S + +  +S  TG+       + ++ +    T L   + S     H
Sbjct: 1858 PVTDASSVSTGHATSLLVTDASSVSTGDTTPLPVTDTNSASTGDTTPLHVTDASSVSTGH 1917

Query: 423  QLA------SSSEVQNGSPMSQTETVSRSVAPMRGGEIT-AHWLLTNSTTSADVT----- 470
              +      SS+   + +P+  T   S S        +T A  + T   TS  VT     
Sbjct: 1918 ATSLPVTSLSSASTGDTTPLPVTSPSSASSGHTTPLPVTDASSVPTGHATSLPVTDASSV 1977

Query: 471  --GSSASYPEGVNASVLT------QFSDSTVQSGGSHTALGDRSYSESSS---------T 513
              G +   P    +SV T        +D++  S G  T L   S S +S+          
Sbjct: 1978 STGHATPLPVTDASSVSTGHATPLPVTDTSSVSTGQATPLPVTSLSSASTGDTTPLPVTD 2037

Query: 514  SSSESLNSSAPRGERSIAGISYGQVRGTAIEQRTSSDHTDHTYL----SSTFTKGERALL 569
            +SS S     P    S++ +S G      +   +S+     T L    +S+ + G    L
Sbjct: 2038 TSSASTGQDTPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDASSVSTGHATSL 2097

Query: 570  SITDNSSSSDIVESSTSYIKISNSSHSEYSSFFHAQTERSNISSYDGEYAQPSTESPVLH 629
             +TD SS S       + + ++++S     S     T    ++S        +T  PV  
Sbjct: 2098 LVTDASSVST---GHATALHVTDAS-----SLSTGDTTPLPVTSPSSASTGDTTPLPVTD 2149

Query: 630  TSNLPS-YTPTINMPNTSVVLDTDAEF--VSDSSSSSS--------SSSSSSSSGPPLPL 678
            TS++ + +  ++ + +TS      A    V+D+SS+S+        + +SS+S+G   PL
Sbjct: 2150 TSSVSTGHATSLPVTDTSSASTGHATSLPVTDTSSASTGHATPLPVTDTSSASTGQATPL 2209

Query: 679  PSVSQSHHLFSSILPSTRASVHLLKSTSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTL 738
            P  S S       +P       L+  TS AST      +PLPV   TS S+  +   T L
Sbjct: 2210 PVTSPSSASTGHAIPL------LVTDTSSAST---GQATPLPV---TSLSSASTGDTTPL 2257

Query: 739  PQSSSTPVLP-RARETPVTSFQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPS 797
            P + ++ V    A   PVTS  + +      +  +S ++     +TP      + + +  
Sbjct: 2258 PVTDASSVSTGHATSLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLHVTDASSASTGH 2317

Query: 798  LVSLPTESTKAVTTNSPLPPSLTESSTEQTLPATSTNLAQMSPTFTTTILKTSQPLMTTP 857
               LP  S  + +T    P  +T  S+  T  AT  ++   S   T      + PL  T 
Sbjct: 2318 ATPLPVTSLSSASTGDTTPLPVTSPSSASTGHATPLHVTDASSVST----GDTTPLPVT- 2372

Query: 858  GTLSSTASLVTGPIAVQTTAGKQLSLTHPEILVPQISTEGGISTERNRV-IVDATTG--- 913
             + SS +S  T P+ V   +      T P  +    S   G +T      +  A+TG   
Sbjct: 2373 -SSSSASSGHTTPLPVTDASSASTGDTTPLPVTDTSSASTGHATHLPVTGLSSASTGDTT 2431

Query: 914  LIPLTSVPTSAKEMTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAED---LAPKSATFAV 970
             +P+T+V +++    T L VT+  S ++      P   T+ VST      L   +++ + 
Sbjct: 2432 RLPVTNVSSASTGHATPLPVTSTSSASTGDTTPLPGTDTSSVSTGHTTPLLVTDASSVST 2491

Query: 971  QSSTQSPTTVSSSAS 985
              +T+ P T  SSAS
Sbjct: 2492 GDTTRLPVTSPSSAS 2506



 Score = 89.7 bits (221), Expect = 2e-17
 Identities = 225/1011 (22%), Positives = 382/1011 (37%), Gaps = 133/1011 (13%)

Query: 19   PLLLLPPAAPGTRDPPPSPARRALSLA-----PLAGAGLELQLERRPEREPPPTPPRERR 73
            PL +  P++  T D  P P     S++     PL   GL         R P         
Sbjct: 3200 PLHVTSPSSASTGDTTPVPVTDTSSVSTGHATPLPVTGLSSASTGDTTRLPVTDISSAST 3259

Query: 74   GPATPGPSYRA---------PEPGAATQRGPSGRA---PRGGSADAAWKHW---PESNTE 118
            G ATP P             P P  +     +G A   P   ++ A+  H    P ++T 
Sbjct: 3260 GQATPLPVTNTSSVSTGDTMPLPVTSPSSASTGHATPLPVTSTSSASTGHATPVPVTSTS 3319

Query: 119  AHVENITFYQNQEDFSTVSSKEGVMVQTSGKSHAASDAPENLTLLAETADARGRSGSSSR 178
            +     T      D S+ S+ +   +  +  S A++     L +   ++ + G + +   
Sbjct: 3320 SASTGHTTPLPVTDTSSASTGDTTPLPVTSPSSASTGHTTPLHVTIPSSASTGDTSTLPV 3379

Query: 179  TNFTILPVGYSLEIATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTASEMGTER 238
            T  +    G++  +    TS      +  L + S SS              +++  G   
Sbjct: 3380 TGASSASTGHATPLPVTDTSSVSTGHATPLPVTSLSSVSTGDTTPLPVTDASSASTGQAT 3439

Query: 239  AMGLSEEWTVHSQEATTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASSP 298
             + ++                   L ++  G+ TTP    ++S   +S  H    A   P
Sbjct: 3440 PLPVTS------------------LSSVSTGD-TTPLLVTDASS--VSTGH----ATPLP 3474

Query: 299  LLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVSKTEG 358
            + D SS+S         T   S+S  Q   + V ++ +     T   L      VS    
Sbjct: 3475 VTDTSSASTGDTTRLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLLVTDASSVSTGHA 3534

Query: 359  FP---KDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQND 415
             P    D+  A+T  +  L  +   S    + T  P       PS+ +    T L     
Sbjct: 3535 TPLPVTDTSSASTGDTTRLPVTDTSSASTGQATPLP----VTIPSSSSSGHTTPL----- 3585

Query: 416  SPTFGEHQLASSSEVQNG--SPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADVTGSS 473
                    + S+S V  G  +P+  T   S S      G +T    L  ++TS+  TG +
Sbjct: 3586 -------PVTSTSSVSTGHVTPLHVTSPSSAST-----GHVTP---LPVTSTSSASTGHA 3630

Query: 474  ASYPEGVNASVLTQFSDSTVQSGGSHTALGDRSYSESSSTSSSESLNSSAPRGERSIAGI 533
                    +SV T  +     +  S  + GD +    + TSS+ S   + P    S++ +
Sbjct: 3631 TPLLVTDASSVSTGHATPLPVTDASSASTGDTTPLPVTDTSSA-STGQATPLPVTSLSSV 3689

Query: 534  SYGQVRGTAIEQRTSSDHTDHTYLS----STFTKGERALLSITDNSSSSDIVESSTSYIK 589
            S G      +   +S+     T L     S+ + G+   L +T  SS+S    +      
Sbjct: 3690 STGDTTPLPVTDASSASTGHATPLPVTIPSSVSTGDTMPLPVTSPSSASTGHATPLPVTG 3749

Query: 590  ISNSSHSEYSSFFHAQTERSNISSYDGEYAQPSTESPVLHTSNLPSYTPTINMPNTSVV- 648
            +S++S  + +      T+ S+ S+      + +T  PV  TS+  S   T  +P T V  
Sbjct: 3750 LSSASTGDTTPL--PVTDTSSAST------RHATPLPVTDTSSA-STDDTTRLPVTDVSS 3800

Query: 649  LDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSILPSTRASVHLLKST--- 705
              T        +S+SS+S+  ++  P     SVS  H   +S+  ++R+S     +T   
Sbjct: 3801 ASTGHATPLPVTSTSSASTGDTTPLPVTDTSSVSTGH--ATSLPVTSRSSASTGHATPLP 3858

Query: 706  -SDASTPWSSSPSPLPVSLTTSTS----APLSVSQTTLPQSSSTPVLPRARETPVTSFQT 760
             +D S+  +   +PLPV+ T+S S     PL V   T P S+ST        TPV    T
Sbjct: 3859 VTDTSSVSTGHATPLPVTSTSSVSTGHATPLPV---TSPSSAST-----GHATPVPVTST 3910

Query: 761  STMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLT 820
            S          S+ T D       +   + T   +P  V+ P+ +++  T+  P+  + +
Sbjct: 3911 S----------SASTGDTTPLPVTNASSLSTGHATPLHVTSPSSASRGDTSTLPVTDA-S 3959

Query: 821  ESSTEQTLPATSTNLAQMSPTFTT----TILKTSQPLMTTPGTLSSTASLVTG-----PI 871
             +ST    P   T+L+ +S   TT    T   ++     TP  ++S +S+ TG     P+
Sbjct: 3960 SASTGHATPLPLTSLSSVSTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPV 4019

Query: 872  AVQTTAGKQLSLTHPEILVPQISTEGGIS---TERNRVIVDATTGLIPLTSVPTSAKEMT 928
             + ++A    + + P      +ST  G     T  +      TT L P+T   +++    
Sbjct: 4020 TIPSSASSGHTTSLPVTDASSVSTGHGTPLPVTSTSSASTGDTTPL-PVTDTSSASTGHA 4078

Query: 929  TKLGVTAEYSPASRSLGTSPSPQTTVVST--AEDLAPKSATFAVQSSTQSP 977
            T L VT   S ++      P    + VST  A  LA  SAT A   S+ SP
Sbjct: 4079 TPLPVTDTSSASTGHATPLPVTSLSSVSTGHATPLAVSSATSASTVSSDSP 4129



 Score = 89.0 bits (219), Expect = 3e-17
 Identities = 209/912 (22%), Positives = 362/912 (39%), Gaps = 112/912 (12%)

Query: 132  DFSTVSSKEGVMVQTSGKSHAASDAPENLTLLAETADARGRSGSSSRTNFTILPVGYSLE 191
            D S+ S+     +  +  S  ++D   +L +   +A + G +     T+ +    G +  
Sbjct: 1413 DTSSASTGHATPLPVTDASSVSTDHATSLPVTIPSAASTGHTTPLPVTDTSSASTGQATS 1472

Query: 192  IATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTASEMGTERAMGLSEEWTVHSQ 251
            +    TS      +  L + S+SS     +      S +++  G    + ++        
Sbjct: 1473 LLVTDTSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSASTGHATPLPVTS-----LS 1527

Query: 252  EATTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASSPLLDLSSSSESTEK 311
             A+T    P  LP      +T+PS                 T  ++PL    +SS ST  
Sbjct: 1528 SASTGDTMP--LP------VTSPSSAS--------------TGDTTPLPVTDASSVST-- 1563

Query: 312  LNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSL---GPVSKTEGFPKDSRIATT 368
              ++T L  +S S   T H   +         +  T  L    P S + G      +  T
Sbjct: 1564 -GHTTPLPVTSPSSASTGHTTPLPVTDTSSASKGDTTPLPVTSPSSASTGHTTPLPVTDT 1622

Query: 369  SSSVLLSPSAVE-SRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQNDSPTFGEHQLA-- 425
            SS+     + +  +  +S  TG+        PS+ +    T L   + S     H     
Sbjct: 1623 SSASTGDTTPLPVTNASSLSTGHATPLHVTSPSSASTGHATPLPVTSTSSASTGHATPLP 1682

Query: 426  ----SSSEVQNGSPMSQTETVSRSVAPMRGGEITA-HWLLTNSTTSADVTGSSASYPEGV 480
                SS+   + + +  T+  S S        +T+   + T  TT   VT  S++     
Sbjct: 1683 VTGLSSATTDDTTRLPVTDVSSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHA 1742

Query: 481  NASVLTQFSDSTVQSGGSHTALGDRSYSESSSTS------SSESLNSSAPRGERSIAGIS 534
            +  ++T  S ++             S S + +T       SS S + +       ++  S
Sbjct: 1743 SPLLVTDASSASTGQATPLPVTDTSSVSTAHATPLPVTGLSSASTDDTTRLPVTDVSSAS 1802

Query: 535  YGQVRGTAIEQRTSSDHTDHTYL----SSTFTKGERALLSITDNSSSSDIVESSTSYIKI 590
             GQ     +   +S+   D T L    +S+ + G+   L +T  SS+S    +S      
Sbjct: 1803 TGQAIPLPVTSPSSASTGDTTPLPVTDASSASTGDTTSLPVTIPSSASSGHTTSLPVTDA 1862

Query: 591  SNSSHSEYSSFFHAQTERSNISSYDGEYAQPSTESPVLHTSNLPSYTPTINMPNTSVVLD 650
            S+ S    +S     T+ S++S+ D      +T  PV  T++  +        +T+ +  
Sbjct: 1863 SSVSTGHATSLL--VTDASSVSTGD------TTPLPVTDTNSAST-------GDTTPLHV 1907

Query: 651  TDAEFVSDSSSSS----SSSSSSSSSGPPLPLPSVSQSHHLFSSILPSTRAS-VHLLKST 705
            TDA  VS   ++S    S SS+S+    PLP+ S S +    ++ LP T AS V    +T
Sbjct: 1908 TDASSVSTGHATSLPVTSLSSASTGDTTPLPVTSPSSASSGHTTPLPVTDASSVPTGHAT 1967

Query: 706  S----DASTPWSSSPSPLPV----SLTTSTSAPLSVSQTTLPQSSSTPVLPRARETPVTS 757
            S    DAS+  +   +PLPV    S++T  + PL V+ T+   S ST    +A   PVTS
Sbjct: 1968 SLPVTDASSVSTGHATPLPVTDASSVSTGHATPLPVTDTS---SVSTG---QATPLPVTS 2021

Query: 758  FQTSTMTSFMTMLHSSQTADLKS-QSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLP 816
              +S  T   T L  + T+   + Q TP     ++   +     LP  S  + +T    P
Sbjct: 2022 L-SSASTGDTTPLPVTDTSSASTGQDTPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATP 2080

Query: 817  PSLTESSTEQTLPATS---TNLAQMSPTFTTTILKTSQPLM----TTPGTLSSTASLVTG 869
              +T++S+  T  ATS   T+ + +S    T +  T    +    TTP  ++S +S  TG
Sbjct: 2081 LLVTDASSVSTGHATSLLVTDASSVSTGHATALHVTDASSLSTGDTTPLPVTSPSSASTG 2140

Query: 870  ---PIAVQTTAGKQLSLTHPEILVPQISTEGGISTERNRVIVD---ATTG---LIPLTSV 920
               P+ V  T+   +S  H   L    ++        +  + D   A+TG    +P+T  
Sbjct: 2141 DTTPLPVTDTS--SVSTGHATSLPVTDTSSASTGHATSLPVTDTSSASTGHATPLPVTDT 2198

Query: 921  PTSAKEMTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAE--DLAPKSATFAVQSST--QS 976
             +++    T L VT   SP+S S G +     T  S+A      P   T    +ST   +
Sbjct: 2199 SSASTGQATPLPVT---SPSSASTGHAIPLLVTDTSSASTGQATPLPVTSLSSASTGDTT 2255

Query: 977  PTTVSSSASVNS 988
            P  V+ ++SV++
Sbjct: 2256 PLPVTDASSVST 2267



 Score = 88.6 bits (218), Expect = 4e-17
 Identities = 224/984 (22%), Positives = 376/984 (38%), Gaps = 136/984 (13%)

Query: 75   PATPGPSYRAPEPGA-ATQRGPSGRAPR--GGSADAAWKHWPESNTEAHVENITFYQNQE 131
            P  P       EPG   T    S   P+  G  A   W     +  EA + + ++   Q 
Sbjct: 530  PRVPSKVSAIGEPGEPTTYSSHSTTLPKTTGAGAQTQWTQETGTTGEALLSSPSYSVTQM 589

Query: 132  DFSTVSSKEGVMVQ-------TSGKS------HAASDAPENLTLLAETADARG-RSGSSS 177
              +  S     M+        T+  S      H+ S +P+    +++    +  ++   S
Sbjct: 590  IKTATSPSSSPMLDRHTSQQITTAPSTNHSTIHSTSTSPQESPAVSQRGHTQAPQTTQES 649

Query: 178  RTNFTILPVGYSLEIATALTS--QSGNLASESLHLPSSSSEFDERIAAFQTKSGTASEMG 235
            +T  ++ P+  +  + T  +S   SG+  SE +   + +       A   T  G  ++  
Sbjct: 650  QTTRSVSPMTDTKTVTTPGSSFTASGHSPSEIVPQDAPTISAATTFAPAPTGDGHTTQAP 709

Query: 236  TERAMGLSEEWTVHSQEATTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAA 295
            T                +  ++ S +    L    ++TP       GP+  W     +A+
Sbjct: 710  TTALQAAPSSHDATLGPSGGTSLSKTGALTLANSVVSTPG------GPEGQWTS--ASAS 761

Query: 296  SSP----LLDLSSSSESTEKLNNS-TGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSL 350
            +SP     +  +  +ESTE    + T   +SS S+T +   AT  + G   T  S +  +
Sbjct: 762  TSPDTAAAMTHTHQAESTEASGQTQTSEPASSGSRTTSAGTATPSSSGASGTTPSGSEGI 821

Query: 351  GPVSKTEGF---PKDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGL 407
                +T  F   P      T S++ LLS SA     +  +  + G    I P T +    
Sbjct: 822  STSGETTRFSSNPSRDSHTTQSTTELLSASA----SHGAIPVSTGMASSIVPGTFHPT-- 875

Query: 408  TSLRWQNDSPTFGEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSA 467
                  +++ T G     SS    + SP  +T  +SR     R         ++ ++ + 
Sbjct: 876  -----LSEASTAGRPTGQSSPTSPSASPQ-ETAAISRMAQTQRTRTSRGSDTISLASQAT 929

Query: 468  DVTGSSASYPEGVNASVLT--QFSDSTVQSGGSH----TALGDRS------YSESSST-- 513
            D   +    P  + ++ LT  Q    T+   GS     TAL   +      Y+ S+ST  
Sbjct: 930  DTFSTVPPTPPSITSTGLTSPQTETHTLSPSGSGKTFTTALISNATPLPVTYASSASTGH 989

Query: 514  --------SSSESLNSSAPRGERSIAGISYGQVRGTAIEQRTSSDHTDH------TYLSS 559
                    +SS S   + P    S + +S G      +   TSS+ T H      T  SS
Sbjct: 990  TTPLHVTDASSVSTGHATPLPVTSPSSVSTGHTTPLPVTD-TSSESTGHVTPLPVTSFSS 1048

Query: 560  TFTKGERALLSITDNSSSSDIVESSTSYIKISNSSHSEYSSFFHAQTERSNISSYDGEYA 619
              T G+   L +TD SS+S    +      +S++S  + +      T  ++         
Sbjct: 1049 AST-GDSTPLPVTDTSSASTGHVTPLPVTSLSSASTGDTTPLPVTDTSSASTGH------ 1101

Query: 620  QPSTESPVLHTSNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLP 679
              +T  PV  TS++ S   T  +P    V DT +     ++S   + +SS S+G   PL 
Sbjct: 1102 --ATSLPVTDTSSV-STGHTTPLP----VTDTSSASTGHATSLPVTDTSSVSTGHTTPLH 1154

Query: 680  SVSQSHHLFSSILPSTRASVHLLKSTSDASTPWSSSPSPLPVSLTTSTSA------PLSV 733
                S    +S   +T   V  L S S   T      +PLPV  T+ +SA      PL V
Sbjct: 1155 VTDASS---ASTGQATPLPVTSLSSVSTGDT------TPLPV--TSPSSASTGHATPLLV 1203

Query: 734  SQTTLPQSSSTPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITES 793
            + T+   +     LP    T  +S  T   TS    + S+ +      +TP      + +
Sbjct: 1204 TDTSSASTGHATPLP---VTDASSVSTDHATSLPVTIPSAAST---GHTTPLPVTDTSSA 1257

Query: 794  KSPSLVSLPTESTKAVTTNSPLPPSLTESSTEQTLPATSTNLAQMSPTFTTTILKTSQPL 853
             +    SL    T +V+T    P  +T +S+  T   T  ++   SP+  +T   T  P+
Sbjct: 1258 STGQATSLLVTDTSSVSTGDTTPLPVTSTSSASTGHVTPLHVT--SPSSASTGHATPLPV 1315

Query: 854  MTTPGTLSSTASLVTGPIAVQTTAGKQLSLTHPEILVPQISTEGGISTERNRVIVDATTG 913
                 +LSS ++  T P+ V + +      T P  +    S   G +T  +  + DA++ 
Sbjct: 1316 T----SLSSASTGDTMPLPVTSPSSASTGDTTPLPVTDASSVSTGHTTPLH--VTDASSA 1369

Query: 914  L------IPLTSVPTSAKEMTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAE--DLAPKS 965
                   +P+TS+ + +   TT L VT   SP+S S G +     T  S+A      P  
Sbjct: 1370 STGQATPLPVTSLSSVSTGDTTPLPVT---SPSSASTGHATPLLVTDTSSASTGHATPLP 1426

Query: 966  ATFAVQSSTQS----PTTVSSSAS 985
             T A   ST      P T+ S+AS
Sbjct: 1427 VTDASSVSTDHATSLPVTIPSAAS 1450



 Score = 85.1 bits (209), Expect = 4e-16
 Identities = 212/925 (22%), Positives = 361/925 (39%), Gaps = 114/925 (12%)

Query: 134  STVSSKEGVMVQTSGKSHAASDAPENLTLLAETADARGRSGSSSRTNFTILPVGYSLEIA 193
            S+ S+ +   +  +  S A++    +L +   ++ + G +     T+ +    G++  + 
Sbjct: 1079 SSASTGDTTPLPVTDTSSASTGHATSLPVTDTSSVSTGHTTPLPVTDTSSASTGHATSLP 1138

Query: 194  TALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTASEMGTERAMGLSEEWTVHSQEA 253
               TS      +  LH+  +SS    +       S ++   G    + ++   +  +  A
Sbjct: 1139 VTDTSSVSTGHTTPLHVTDASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHA 1198

Query: 254  T------TSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASSPLLDLSSSSE 307
            T      TS+ S      L + + ++ S    +S P ++      T  ++PL    +SS 
Sbjct: 1199 TPLLVTDTSSASTGHATPLPVTDASSVSTDHATSLP-VTIPSAASTGHTTPLPVTDTSSA 1257

Query: 308  STEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVSKTEGFPKDSRIAT 367
            ST         Q++S+  T T  V+T  T   P T  S + S G V+     P      +
Sbjct: 1258 STG--------QATSLLVTDTSSVSTGDTTPLPVTSTS-SASTGHVT-----PLHVTSPS 1303

Query: 368  TSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQNDSPTFGEHQLASS 427
            ++S+   +P  V S  +S  TG+        PS+ +    T L   +          ASS
Sbjct: 1304 SASTGHATPLPVTSL-SSASTGDTMPLPVTSPSSASTGDTTPLPVTD----------ASS 1352

Query: 428  SEVQNGSPMSQTETVSRSVAPMRGGEITA-HWLLTNSTTSADVTGSSASYPEGVNASVLT 486
                + +P+  T+  S S        +T+   + T  TT   VT  S++        ++T
Sbjct: 1353 VSTGHTTPLHVTDASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVT 1412

Query: 487  QFSDSTVQSGGSHTALGDRSYSESSSTSSSESLNSSAPRGERS------IAGISYGQVRG 540
              S ++             S S   +TS   ++ S+A  G  +       +  S GQ   
Sbjct: 1413 DTSSASTGHATPLPVTDASSVSTDHATSLPVTIPSAASTGHTTPLPVTDTSSASTGQATS 1472

Query: 541  TAIEQRTSSDHTDHTYLSSTFTK----GERALLSITDNSSSSDIVESSTSYIKISNSSHS 596
              +   +S    D T L  T T     G    L +T  SS+S     +T     S SS S
Sbjct: 1473 LLVTDTSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSAS--TGHATPLPVTSLSSAS 1530

Query: 597  EYSSFFHAQTERSNISSYDGEYAQPSTESPVL--HTSNLPSYTPTINMPNTSV---VLDT 651
               +     T  S+ S+ D      +  S V   HT+ LP  +P+      +    V DT
Sbjct: 1531 TGDTMPLPVTSPSSASTGDTTPLPVTDASSVSTGHTTPLPVTSPSSASTGHTTPLPVTDT 1590

Query: 652  DAEFVSDSSSSSSSSSSSSSSG--PPLPLPSVSQSHHLFSSILPSTRASVHLLKSTSDAS 709
             +    D++    +S SS+S+G   PLP+   S +    ++ LP T AS     ST  A+
Sbjct: 1591 SSASKGDTTPLPVTSPSSASTGHTTPLPVTDTSSASTGDTTPLPVTNASS---LSTGHAT 1647

Query: 710  TPWSSSPSPLPVSLTTSTSA------PLSVSQTT---------LP----QSSSTPVLPRA 750
                      P+ +T+ +SA      PL V+ T+         LP     S++T    R 
Sbjct: 1648 ----------PLHVTSPSSASTGHATPLPVTSTSSASTGHATPLPVTGLSSATTDDTTRL 1697

Query: 751  RETPVTSFQTSTMTSF-MTMLHSSQTADL--------KSQSTPHQEK-VITESKSPS--- 797
              T V+S  T   T   +T L S  T D          S ST H    ++T++ S S   
Sbjct: 1698 PVTDVSSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHASPLLVTDASSASTGQ 1757

Query: 798  LVSLPTESTKAVTT--NSPLP-PSLTESSTEQT--LPATSTNLAQMSPTFTTTILKTSQ- 851
               LP   T +V+T   +PLP   L+ +ST+ T  LP T  + A         +   S  
Sbjct: 1758 ATPLPVTDTSSVSTAHATPLPVTGLSSASTDDTTRLPVTDVSSASTGQAIPLPVTSPSSA 1817

Query: 852  ------PLMTTPGTLSSTASLVTGPIAVQTTAGKQLSLTHPEILVPQISTEGGIS---TE 902
                  PL  T  + +ST    + P+ + ++A    + + P      +ST    S   T+
Sbjct: 1818 STGDTTPLPVTDASSASTGDTTSLPVTIPSSASSGHTTSLPVTDASSVSTGHATSLLVTD 1877

Query: 903  RNRVIVDATTGLIPLTSVPTSAKEMTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAEDL- 961
             + V    TT L P+T   +++   TT L VT   S ++    + P    +  ST +   
Sbjct: 1878 ASSVSTGDTTPL-PVTDTNSASTGDTTPLHVTDASSVSTGHATSLPVTSLSSASTGDTTP 1936

Query: 962  APKSATFAVQSSTQSPTTVSSSASV 986
             P ++  +  S   +P  V+ ++SV
Sbjct: 1937 LPVTSPSSASSGHTTPLPVTDASSV 1961



 Score = 67.8 bits (164), Expect = 7e-11
 Identities = 145/624 (23%), Positives = 241/624 (38%), Gaps = 83/624 (13%)

Query: 416 SPTFGEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADVTGSSAS 475
           S T  +   ASS   Q  S  + ++  + ++  M    + +   + N   +A     + S
Sbjct: 63  SRTSNQDISASSQNHQTKSTETTSKAQTDTLTQMMTSTLFSSPSVHNVMETAPPDEMTTS 122

Query: 476 YPEGVNASVLTQFSDSTVQSGGSHTALGDRSYSESSSTSSSESLNSSAPRGERSIAGISY 535
           +P  V  + L   S +   +  + + LG+   + ++ T SS  + S+      SI     
Sbjct: 123 FPSSVT-NTLMMTSKTITMTTSTDSTLGNTEETSTAGTESSTPVTSAV-----SITAGQE 176

Query: 536 GQVRGTAIE---QRTSSDHTDHTYLSSTFTKGERALLSITDNSSS----SDIVESSTSYI 588
           GQ R T+     Q TS+   +H +  ST T  E    ++T  ++S    S  V + T  +
Sbjct: 177 GQSRTTSWRTSIQDTSASSQNH-WTRSTQTTRESQTSTLTHRTTSTPSFSPSVHNVTGTV 235

Query: 589 KISNSSHSEYSSFFHAQTERSNISSYDGEYAQPSTESPVLHTSNLPSYTPTIN-MPNTSV 647
               S   E ++        +++ + +      ST S + +     S   T + MP TS 
Sbjct: 236 SQKTSPSGETATSSLCSVTNTSMMTSEKITVTTSTGSTLGNPGETSSVPVTGSLMPVTSA 295

Query: 648 VLDT-DAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSH----HLFSSILPSTRASVHLL 702
            L T D E  S ++ S +S+  +++        SV  +     +  +++ P T ++V  L
Sbjct: 296 ALVTFDPEGQSPATFSRTSTQDTTAFSKNHQTQSVETTRVSQINTLNTLTPVTTSTV--L 353

Query: 703 KSTSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQS-------SSTPVLPRARETPV 755
            S S  +   + S    P   TT TS+P SVS T L  S       S    L    ET +
Sbjct: 354 SSPSGFNPSGTVSQETFPSGETT-TSSPSSVSNTFLVTSKVFRMPTSRDSTLGNTEETSL 412

Query: 756 TSFQT-STMTS-----------------------FMTMLHSSQTADLKSQSTPHQEKVIT 791
           +   T S +TS                         T  H+ Q+   ++   PH+    +
Sbjct: 413 SVSGTISAITSKVSTIWWSDTLSTALSPSSLPPKISTAFHTQQSEGAETTGRPHERSSFS 472

Query: 792 ESKSPSLVSLPTESTKAVTTNSPLPPSLTESSTEQTLPATSTNLAQMSPTFTTTILKTSQ 851
              S  + +L   +T   + +S      T S TE  LP+TST  A        T L T  
Sbjct: 473 PGVSQEIFTLHETTTWPSSFSSK--GHTTWSQTE--LPSTSTGAA--------TRLVTGN 520

Query: 852 PLMTTPGTLSSTASLVT--GPIAVQTTAGKQLSLTHPEILVPQISTEGGISTERNRVIVD 909
           P   T GT+    S V+  G     TT     S T P+      +T  G  T+  +    
Sbjct: 521 PSTGTAGTIPRVPSKVSAIGEPGEPTTYSSH-STTLPK------TTGAGAQTQWTQET-- 571

Query: 910 ATTGLIPLTSVPTSAKEMTTKLGVTAEYSP-----ASRSLGTSPSPQTTVVSTAEDLAPK 964
            TTG   L+S   S  +M  K   +   SP      S+ + T+PS   + + +      +
Sbjct: 572 GTTGEALLSSPSYSVTQMI-KTATSPSSSPMLDRHTSQQITTAPSTNHSTIHSTSTSPQE 630

Query: 965 SATFAVQSSTQSPTTVSSSASVNS 988
           S   + +  TQ+P T   S +  S
Sbjct: 631 SPAVSQRGHTQAPQTTQESQTTRS 654



 Score = 63.9 bits (154), Expect = 1e-09
 Identities = 168/713 (23%), Positives = 277/713 (38%), Gaps = 128/713 (17%)

Query: 132  DFSTVSSKEGVMVQTSGKSHAASDAPENLTLLAETADARGRS--------GSSSRTNFTI 183
            D S+VS+     +  +  S A++     L +   ++ + G++         SSS  + T 
Sbjct: 3525 DASSVSTGHATPLPVTDTSSASTGDTTRLPVTDTSSASTGQATPLPVTIPSSSSSGHTTP 3584

Query: 184  LPVGYSLEIATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTASEMGTERAMGLS 243
            LPV  +  ++T   +         LH+ S SS     +      S +++  G    + ++
Sbjct: 3585 LPVTSTSSVSTGHVTP--------LHVTSPSSASTGHVTPLPVTSTSSASTGHATPLLVT 3636

Query: 244  EEWTVHSQEATTSAWSPSFLPALEMGEL----TTPSRKRNSSGPDLSWLHFYRTAASSPL 299
            +  +V +  AT        LP  +        TTP    ++S           T  ++PL
Sbjct: 3637 DASSVSTGHATP-------LPVTDASSASTGDTTPLPVTDTSSAS--------TGQATPL 3681

Query: 300  LDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVSKTEGF 359
               S SS ST    ++T L  +  S   T H   +     P T+ S       VS  +  
Sbjct: 3682 PVTSLSSVST---GDTTPLPVTDASSASTGHATPL-----PVTIPS------SVSTGDTM 3727

Query: 360  PKDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQNDSPTF 419
            P      +++S+   +P  V    +S  TG+       + S+ +    T L   + S   
Sbjct: 3728 PLPVTSPSSASTGHATPLPVTGL-SSASTGDTTPLPVTDTSSASTRHATPLPVTDTSSAS 3786

Query: 420  GEHQL------ASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADVTGSS 473
             +          SS+   + +P+  T T S S      G+ T    L  + TS+  TG +
Sbjct: 3787 TDDTTRLPVTDVSSASTGHATPLPVTSTSSAST-----GDTTP---LPVTDTSSVSTGHA 3838

Query: 474  ASYPEGVNASVLTQFSDSTVQSGGSHTALGDRSYSESSSTSSSESLNSSAPRGERSIAGI 533
             S P    +S  T  +     +  S  + G  +    +STSS  S   + P    S +  
Sbjct: 3839 TSLPVTSRSSASTGHATPLPVTDTSSVSTGHATPLPVTSTSSV-STGHATPLPVTSPSSA 3897

Query: 534  SYGQVRGTAIEQRTSSDHTDHTYL----SSTFTKGERALLSITDNSSSSDIVESSTSYIK 589
            S G      +   +S+   D T L    +S+ + G    L +T  SS+S      TS + 
Sbjct: 3898 STGHATPVPVTSTSSASTGDTTPLPVTNASSLSTGHATPLHVTSPSSAS---RGDTSTLP 3954

Query: 590  ISNSSHSEYSSFFHAQ----TERSNISSYDGEYAQPSTESPVLHTSNLPSYTPTINMPNT 645
            ++++S +   S  HA     T  S++S+ D      +T  PV  TS+  +   T  +P T
Sbjct: 3955 VTDASSA---STGHATPLPLTSLSSVSTGD------TTPLPVTDTSSASTGQAT-PLPVT 4004

Query: 646  SVVL----DTDAEFVSDSSSSSS----------SSSSSSSSGPPLPLPSVSQSHHLFSSI 691
            S+      DT    V+  SS+SS          +SS S+  G PLP+ S S +    ++ 
Sbjct: 4005 SLSSVSTGDTTPLPVTIPSSASSGHTTSLPVTDASSVSTGHGTPLPVTSTSSASTGDTTP 4064

Query: 692  LPSTRASV----HLLK-STSDASTPWSSSPSPLPV----SLTTSTSAPLSVSQTTLPQSS 742
            LP T  S     H      +D S+  +   +PLPV    S++T  + PL+VS  T   + 
Sbjct: 4065 LPVTDTSSASTGHATPLPVTDTSSASTGHATPLPVTSLSSVSTGHATPLAVSSATSASTV 4124

Query: 743  S-------------TPVLPR------ARETPVTSFQTSTMTSFMTMLHSSQTA 776
            S             TP L        A   P T+ QT   T   T +H+  TA
Sbjct: 4125 SSDSPLKMETPGMTTPSLKTDGGRRTATSPPPTTSQTIISTIPSTAMHTRSTA 4177



 Score = 45.1 bits (105), Expect = 5e-04
 Identities = 80/316 (25%), Positives = 122/316 (38%), Gaps = 37/316 (11%)

Query: 700 HLLKSTSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLP---------------QSSST 744
           H++  T++  T  + S +  PV+ T ST+A L    T                  Q+ ST
Sbjct: 24  HVVPGTTE-DTLITGSKTAAPVTSTGSTTATLEGQSTAASSRTSNQDISASSQNHQTKST 82

Query: 745 PVLPRARETPVTSFQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTE 804
               +A+   +T   TST+ S  ++ +  +TA     +T     V       S     T 
Sbjct: 83  ETTSKAQTDTLTQMMTSTLFSSPSVHNVMETAPPDEMTTSFPSSVTNTLMMTSKTITMTT 142

Query: 805 STKAVTTNSPLPPSL-TESSTEQTLPATSTNLAQMSPTFTTTILKTSQPLMTTPGTLSST 863
           ST +   N+    +  TESST  T  A S    Q   + TT+   + Q         +S 
Sbjct: 143 STDSTLGNTEETSTAGTESSTPVT-SAVSITAGQEGQSRTTSWRTSIQD--------TSA 193

Query: 864 ASLVTGPIAVQTTAGKQLS-LTHPEILVPQIS-----TEGGISTERNRVIVDATTGL--I 915
           +S      + QTT   Q S LTH     P  S       G +S + +     AT+ L  +
Sbjct: 194 SSQNHWTRSTQTTRESQTSTLTHRTTSTPSFSPSVHNVTGTVSQKTSPSGETATSSLCSV 253

Query: 916 PLTSVPTSAK-EMTTKLGVTAEYSPASRSLGTSPS--PQTTVVSTAEDLAPKSATFAVQS 972
             TS+ TS K  +TT  G T      + S+  + S  P T+      D   +S     ++
Sbjct: 254 TNTSMMTSEKITVTTSTGSTLGNPGETSSVPVTGSLMPVTSAALVTFDPEGQSPATFSRT 313

Query: 973 STQSPTTVSSSASVNS 988
           STQ  T  S +    S
Sbjct: 314 STQDTTAFSKNHQTQS 329



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 130/618 (21%), Positives = 234/618 (37%), Gaps = 100/618 (16%)

Query: 132  DFSTVSSKEGVMVQTSGKSHAASDAPENLTLLAETADARGRSGSSSRTNFTILPVGYS-- 189
            D S+VS+     +  +  S A++     L +   ++ + G++     T+ + +  G +  
Sbjct: 3637 DASSVSTGHATPLPVTDASSASTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTP 3696

Query: 190  LEIATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTASEMGTERAM-GLSEEWTV 248
            L +  A ++ +G+     + +PSS S  D       + S  ++   T   + GLS     
Sbjct: 3697 LPVTDASSASTGHATPLPVTIPSSVSTGDTMPLPVTSPSSASTGHATPLPVTGLSS---- 3752

Query: 249  HSQEATTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASSPLLDLSSSSES 308
                A+T   +P  LP  +    +T                  R A   P+ D SS+S  
Sbjct: 3753 ----ASTGDTTP--LPVTDTSSAST------------------RHATPLPVTDTSSAST- 3787

Query: 309  TEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVSKTEGFPKDSRIATT 368
                +++T L  + VS   T H   +       T  + T    P+  T+         T+
Sbjct: 3788 ----DDTTRLPVTDVSSASTGHATPLPVTS---TSSASTGDTTPLPVTD---------TS 3831

Query: 369  SSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQNDSPTFGEHQLA--- 425
            S S   + S   + R+S  TG+       + S+ +    T L   + S     H      
Sbjct: 3832 SVSTGHATSLPVTSRSSASTGHATPLPVTDTSSVSTGHATPLPVTSTSSVSTGHATPLPV 3891

Query: 426  ---SSSEVQNGSPMSQTETVSRSVAPMRGGEIT-AHWLLTNSTTSADVTGSSASYPEGVN 481
               SS+   + +P+  T T S S        +T A  L T   T   VT  S++     +
Sbjct: 3892 TSPSSASTGHATPVPVTSTSSASTGDTTPLPVTNASSLSTGHATPLHVTSPSSASRGDTS 3951

Query: 482  ASVLTQFSDSTVQSGGSHTALGDRSYSESSS---------TSSSESLNSSAPRGERSIAG 532
               +T   D++  S G  T L   S S  S+          +SS S   + P    S++ 
Sbjct: 3952 TLPVT---DASSASTGHATPLPLTSLSSVSTGDTTPLPVTDTSSASTGQATPLPVTSLSS 4008

Query: 533  ISYGQVRG--TAIEQRTSSDHTDHTYLS--STFTKGERALLSITDNSSSSDIVESSTSYI 588
            +S G        I    SS HT    ++  S+ + G    L +T  SS+S      T+ +
Sbjct: 4009 VSTGDTTPLPVTIPSSASSGHTTSLPVTDASSVSTGHGTPLPVTSTSSAST---GDTTPL 4065

Query: 589  KISNSSHSEYSSFFHAQTERSNISSYDGEYAQPSTESPVLHTSNLPS-YTPTINMPNTSV 647
             ++++S +   S  HA                  T  PV  TS+  + +   + + + S 
Sbjct: 4066 PVTDTSSA---STGHA------------------TPLPVTDTSSASTGHATPLPVTSLSS 4104

Query: 648  VLDTDAEFVSDSSSSSSSSSSSSS----SGPPLPLPSVSQSHHLFSSILPSTRASVHLLK 703
            V    A  ++ SS++S+S+ SS S      P +  PS+       ++  P    S  ++ 
Sbjct: 4105 VSTGHATPLAVSSATSASTVSSDSPLKMETPGMTTPSLKTDGGRRTATSPPPTTSQTIIS 4164

Query: 704  STSDASTPWSSSPSPLPV 721
            +    +    S+ +P+P+
Sbjct: 4165 TIPSTAMHTRSTAAPIPI 4182


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score = 95.5 bits (236), Expect = 3e-19
 Identities = 89/384 (23%), Positives = 157/384 (40%), Gaps = 31/384 (8%)

Query: 623  TESPVLHTSNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVS 682
            T+   + T+   + TP    P T+    T     + + + +++  +++++  P P P+ +
Sbjct: 1880 TQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 1939

Query: 683  QSH-----HLFSSILPSTRASVHLLKSTSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTT 737
            Q+         +++ P+   +     +T+  +T  + +P+P P    T T+ P++ + T 
Sbjct: 1940 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 1999

Query: 738  LPQSSSTPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPS 797
             P  + T        TP+T+  T T T   T   +  T  + + +T      +T + +P+
Sbjct: 2000 TPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT------VTPTPTPT 2052

Query: 798  LVSLPTESTKAVTTNSPLPPSLTESSTEQTLPATSTNLAQMSPTFTTTILKTSQPLMTT- 856
                PT +    TT     P+ T + T  T P T+T     +PT T T   T+ P+ TT 
Sbjct: 2053 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2112

Query: 857  ----PGTLSSTASLVTGPIAVQTT-------AGKQLSLTHP---EILVPQISTEGGISTE 902
                  T + T +  T PI   TT        G Q   T P      V    T  G  T 
Sbjct: 2113 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2172

Query: 903  RNRVIVDATTGLIPLTSVPTSAK-EMTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAEDL 961
                I   TT  +  T  PT  +   TT +  T   +P     GT  +P TT ++T   +
Sbjct: 2173 TTTPITTTTT--VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTV 2229

Query: 962  APKSATFAVQSSTQSPTTVSSSAS 985
             P       Q+ T +P T +++ +
Sbjct: 2230 TPTPTPTGTQTPTTTPITTTTTVT 2253



 Score = 90.9 bits (224), Expect = 8e-18
 Identities = 151/789 (19%), Positives = 294/789 (37%), Gaps = 81/789 (10%)

Query: 254  TTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASSPLLDLSSSSESTEKLN 313
            TT+  +P+  P       TTP     +  P  +      T   +P     +++ +     
Sbjct: 1972 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-----PTGTQTPTTTPITTTTTVTPTP 2026

Query: 314  NSTGLQSSSVSQ-TKTMHVATVFTDGGPRT------LRSLTVSLGPVSKTEGFPKDSRIA 366
              TG Q+ + +  T T  V    T  G +T        + TV+  P       P  + I 
Sbjct: 2027 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2086

Query: 367  TTSSSV-------LLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQNDSPTF 419
            TT++           +P+       + VT  P       P+T     +T+      +PT 
Sbjct: 2087 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP---ITTTTTVTPTPT- 2142

Query: 420  GEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADVTGSSASYPEG 479
                  + ++    +P++ T TV+ +  P      T   + T +T +   T      P G
Sbjct: 2143 -----PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTG 2191

Query: 480  VNASVLTQFSDSTVQSGGSHTALGDRSYSESSSTSSSESLNSSAPRGERSIAGISYGQVR 539
                  T  + +T  +  + T  G ++ + +  T+++    +  P G ++          
Sbjct: 2192 TQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2250

Query: 540  GTAIEQRTSSDHTDHTYLSSTFTKGERALLSITDNSSSSDIVESSTSYIKISNSSHSEYS 599
                    +   T  T   +T T            + ++  + ++T+       + ++  
Sbjct: 2251 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2310

Query: 600  SFFHAQTERSNISSYDGEYAQPSTESPVLHTSNL-PSYTPT-----INMPNTSVVLDTDA 653
            +     T  +   +      Q  T +P+  T+ + P+ TPT        P T+    T  
Sbjct: 2311 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2370

Query: 654  EFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLF-----SSILPSTRASVHLLKSTSDA 708
               + + + +++  +++++  P P P+ +Q+         +++ P+   +     +T+  
Sbjct: 2371 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2430

Query: 709  STPWSSSPSPLPVSLTTSTSAPLSVSQT--------------TLPQSSSTPVLPRARETP 754
            +T  + +P+P P    T T+ P++ + T              T P +++T V P    T 
Sbjct: 2431 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2490

Query: 755  VTSFQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSP 814
              +  T+ +T+  T+  +      ++ +T       T + +P+     T +T  +TT + 
Sbjct: 2491 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2550

Query: 815  LPPSLTESSTE--QTLPATSTNLAQMSPTFTTTILKTSQPLMTT-----PGTLSSTASLV 867
            + P+ T + T+   T P T+T     +PT T T   T+ P+ TT       T + T +  
Sbjct: 2551 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2610

Query: 868  TGPIAVQTT-------AGKQLSLTHP---EILVPQISTEGGISTERNRVIVDATTGLIPL 917
            T PI   TT        G Q   T P      V    T  G  T     I   TT  +  
Sbjct: 2611 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--VTP 2668

Query: 918  TSVPTSAK-EMTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSATFAVQSSTQS 976
            T  PT  +   TT +  T   +P     GT  +P TT ++T   + P       Q+ T +
Sbjct: 2669 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTT 2727

Query: 977  PTTVSSSAS 985
            P T +++ +
Sbjct: 2728 PITTTTTVT 2736



 Score = 90.9 bits (224), Expect = 8e-18
 Identities = 151/789 (19%), Positives = 294/789 (37%), Gaps = 81/789 (10%)

Query: 254  TTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASSPLLDLSSSSESTEKLN 313
            TT+  +P+  P       TTP     +  P  +      T   +P     +++ +     
Sbjct: 2110 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-----PTGTQTPTTTPITTTTTVTPTP 2164

Query: 314  NSTGLQSSSVSQ-TKTMHVATVFTDGGPRT------LRSLTVSLGPVSKTEGFPKDSRIA 366
              TG Q+ + +  T T  V    T  G +T        + TV+  P       P  + I 
Sbjct: 2165 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2224

Query: 367  TTSSSV-------LLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQNDSPTF 419
            TT++           +P+       + VT  P       P+T     +T+      +PT 
Sbjct: 2225 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP---ITTTTTVTPTPT- 2280

Query: 420  GEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADVTGSSASYPEG 479
                  + ++    +P++ T TV+ +  P      T   + T +T +   T      P G
Sbjct: 2281 -----PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTG 2329

Query: 480  VNASVLTQFSDSTVQSGGSHTALGDRSYSESSSTSSSESLNSSAPRGERSIAGISYGQVR 539
                  T  + +T  +  + T  G ++ + +  T+++    +  P G ++          
Sbjct: 2330 TQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2388

Query: 540  GTAIEQRTSSDHTDHTYLSSTFTKGERALLSITDNSSSSDIVESSTSYIKISNSSHSEYS 599
                    +   T  T   +T T            + ++  + ++T+       + ++  
Sbjct: 2389 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2448

Query: 600  SFFHAQTERSNISSYDGEYAQPSTESPVLHTSNL-PSYTPT-----INMPNTSVVLDTDA 653
            +     T  +   +      Q  T +P+  T+ + P+ TPT        P T+    T  
Sbjct: 2449 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2508

Query: 654  EFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLF-----SSILPSTRASVHLLKSTSDA 708
               + + + +++  +++++  P P P+ +Q+         +++ P+   +     +T+  
Sbjct: 2509 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2568

Query: 709  STPWSSSPSPLPVSLTTSTSAPLSVSQT--------------TLPQSSSTPVLPRARETP 754
            +T  + +P+P P    T T+ P++ + T              T P +++T V P    T 
Sbjct: 2569 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2628

Query: 755  VTSFQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSP 814
              +  T+ +T+  T+  +      ++ +T       T + +P+     T +T  +TT + 
Sbjct: 2629 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2688

Query: 815  LPPSLTESSTE--QTLPATSTNLAQMSPTFTTTILKTSQPLMTT-----PGTLSSTASLV 867
            + P+ T + T+   T P T+T     +PT T T   T+ P+ TT       T + T +  
Sbjct: 2689 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2748

Query: 868  TGPIAVQTT-------AGKQLSLTHP---EILVPQISTEGGISTERNRVIVDATTGLIPL 917
            T PI   TT        G Q   T P      V    T  G  T     I   TT  +  
Sbjct: 2749 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--VTP 2806

Query: 918  TSVPTSAK-EMTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSATFAVQSSTQS 976
            T  PT  +   TT +  T   +P     GT  +P TT ++T   + P       Q+ T +
Sbjct: 2807 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTT 2865

Query: 977  PTTVSSSAS 985
            P T +++ +
Sbjct: 2866 PITTTTTVT 2874



 Score = 90.9 bits (224), Expect = 8e-18
 Identities = 151/789 (19%), Positives = 294/789 (37%), Gaps = 81/789 (10%)

Query: 254  TTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASSPLLDLSSSSESTEKLN 313
            TT+  +P+  P       TTP     +  P  +      T   +P     +++ +     
Sbjct: 2248 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-----PTGTQTPTTTPITTTTTVTPTP 2302

Query: 314  NSTGLQSSSVSQ-TKTMHVATVFTDGGPRT------LRSLTVSLGPVSKTEGFPKDSRIA 366
              TG Q+ + +  T T  V    T  G +T        + TV+  P       P  + I 
Sbjct: 2303 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2362

Query: 367  TTSSSV-------LLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQNDSPTF 419
            TT++           +P+       + VT  P       P+T     +T+      +PT 
Sbjct: 2363 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP---ITTTTTVTPTPT- 2418

Query: 420  GEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADVTGSSASYPEG 479
                  + ++    +P++ T TV+ +  P      T   + T +T +   T      P G
Sbjct: 2419 -----PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTG 2467

Query: 480  VNASVLTQFSDSTVQSGGSHTALGDRSYSESSSTSSSESLNSSAPRGERSIAGISYGQVR 539
                  T  + +T  +  + T  G ++ + +  T+++    +  P G ++          
Sbjct: 2468 TQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2526

Query: 540  GTAIEQRTSSDHTDHTYLSSTFTKGERALLSITDNSSSSDIVESSTSYIKISNSSHSEYS 599
                    +   T  T   +T T            + ++  + ++T+       + ++  
Sbjct: 2527 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2586

Query: 600  SFFHAQTERSNISSYDGEYAQPSTESPVLHTSNL-PSYTPT-----INMPNTSVVLDTDA 653
            +     T  +   +      Q  T +P+  T+ + P+ TPT        P T+    T  
Sbjct: 2587 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2646

Query: 654  EFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLF-----SSILPSTRASVHLLKSTSDA 708
               + + + +++  +++++  P P P+ +Q+         +++ P+   +     +T+  
Sbjct: 2647 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2706

Query: 709  STPWSSSPSPLPVSLTTSTSAPLSVSQT--------------TLPQSSSTPVLPRARETP 754
            +T  + +P+P P    T T+ P++ + T              T P +++T V P    T 
Sbjct: 2707 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2766

Query: 755  VTSFQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSP 814
              +  T+ +T+  T+  +      ++ +T       T + +P+     T +T  +TT + 
Sbjct: 2767 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2826

Query: 815  LPPSLTESSTE--QTLPATSTNLAQMSPTFTTTILKTSQPLMTT-----PGTLSSTASLV 867
            + P+ T + T+   T P T+T     +PT T T   T+ P+ TT       T + T +  
Sbjct: 2827 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2886

Query: 868  TGPIAVQTT-------AGKQLSLTHP---EILVPQISTEGGISTERNRVIVDATTGLIPL 917
            T PI   TT        G Q   T P      V    T  G  T     I   TT  +  
Sbjct: 2887 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--VTP 2944

Query: 918  TSVPTSAK-EMTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSATFAVQSSTQS 976
            T  PT  +   TT +  T   +P     GT  +P TT ++T   + P       Q+ T +
Sbjct: 2945 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTT 3003

Query: 977  PTTVSSSAS 985
            P T +++ +
Sbjct: 3004 PITTTTTVT 3012



 Score = 90.9 bits (224), Expect = 8e-18
 Identities = 151/789 (19%), Positives = 294/789 (37%), Gaps = 81/789 (10%)

Query: 254  TTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASSPLLDLSSSSESTEKLN 313
            TT+  +P+  P       TTP     +  P  +      T   +P     +++ +     
Sbjct: 2386 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-----PTGTQTPTTTPITTTTTVTPTP 2440

Query: 314  NSTGLQSSSVSQ-TKTMHVATVFTDGGPRT------LRSLTVSLGPVSKTEGFPKDSRIA 366
              TG Q+ + +  T T  V    T  G +T        + TV+  P       P  + I 
Sbjct: 2441 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2500

Query: 367  TTSSSV-------LLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQNDSPTF 419
            TT++           +P+       + VT  P       P+T     +T+      +PT 
Sbjct: 2501 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP---ITTTTTVTPTPT- 2556

Query: 420  GEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADVTGSSASYPEG 479
                  + ++    +P++ T TV+ +  P      T   + T +T +   T      P G
Sbjct: 2557 -----PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTG 2605

Query: 480  VNASVLTQFSDSTVQSGGSHTALGDRSYSESSSTSSSESLNSSAPRGERSIAGISYGQVR 539
                  T  + +T  +  + T  G ++ + +  T+++    +  P G ++          
Sbjct: 2606 TQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2664

Query: 540  GTAIEQRTSSDHTDHTYLSSTFTKGERALLSITDNSSSSDIVESSTSYIKISNSSHSEYS 599
                    +   T  T   +T T            + ++  + ++T+       + ++  
Sbjct: 2665 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2724

Query: 600  SFFHAQTERSNISSYDGEYAQPSTESPVLHTSNL-PSYTPT-----INMPNTSVVLDTDA 653
            +     T  +   +      Q  T +P+  T+ + P+ TPT        P T+    T  
Sbjct: 2725 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2784

Query: 654  EFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLF-----SSILPSTRASVHLLKSTSDA 708
               + + + +++  +++++  P P P+ +Q+         +++ P+   +     +T+  
Sbjct: 2785 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2844

Query: 709  STPWSSSPSPLPVSLTTSTSAPLSVSQT--------------TLPQSSSTPVLPRARETP 754
            +T  + +P+P P    T T+ P++ + T              T P +++T V P    T 
Sbjct: 2845 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2904

Query: 755  VTSFQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSP 814
              +  T+ +T+  T+  +      ++ +T       T + +P+     T +T  +TT + 
Sbjct: 2905 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2964

Query: 815  LPPSLTESSTE--QTLPATSTNLAQMSPTFTTTILKTSQPLMTT-----PGTLSSTASLV 867
            + P+ T + T+   T P T+T     +PT T T   T+ P+ TT       T + T +  
Sbjct: 2965 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3024

Query: 868  TGPIAVQTT-------AGKQLSLTHP---EILVPQISTEGGISTERNRVIVDATTGLIPL 917
            T PI   TT        G Q   T P      V    T  G  T     I   TT  +  
Sbjct: 3025 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--VTP 3082

Query: 918  TSVPTSAK-EMTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSATFAVQSSTQS 976
            T  PT  +   TT +  T   +P     GT  +P TT ++T   + P       Q+ T +
Sbjct: 3083 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTT 3141

Query: 977  PTTVSSSAS 985
            P T +++ +
Sbjct: 3142 PITTTTTVT 3150



 Score = 90.9 bits (224), Expect = 8e-18
 Identities = 151/789 (19%), Positives = 294/789 (37%), Gaps = 81/789 (10%)

Query: 254  TTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASSPLLDLSSSSESTEKLN 313
            TT+  +P+  P       TTP     +  P  +      T   +P     +++ +     
Sbjct: 2524 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-----PTGTQTPTTTPITTTTTVTPTP 2578

Query: 314  NSTGLQSSSVSQ-TKTMHVATVFTDGGPRT------LRSLTVSLGPVSKTEGFPKDSRIA 366
              TG Q+ + +  T T  V    T  G +T        + TV+  P       P  + I 
Sbjct: 2579 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2638

Query: 367  TTSSSV-------LLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQNDSPTF 419
            TT++           +P+       + VT  P       P+T     +T+      +PT 
Sbjct: 2639 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP---ITTTTTVTPTPT- 2694

Query: 420  GEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADVTGSSASYPEG 479
                  + ++    +P++ T TV+ +  P      T   + T +T +   T      P G
Sbjct: 2695 -----PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTG 2743

Query: 480  VNASVLTQFSDSTVQSGGSHTALGDRSYSESSSTSSSESLNSSAPRGERSIAGISYGQVR 539
                  T  + +T  +  + T  G ++ + +  T+++    +  P G ++          
Sbjct: 2744 TQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2802

Query: 540  GTAIEQRTSSDHTDHTYLSSTFTKGERALLSITDNSSSSDIVESSTSYIKISNSSHSEYS 599
                    +   T  T   +T T            + ++  + ++T+       + ++  
Sbjct: 2803 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2862

Query: 600  SFFHAQTERSNISSYDGEYAQPSTESPVLHTSNL-PSYTPT-----INMPNTSVVLDTDA 653
            +     T  +   +      Q  T +P+  T+ + P+ TPT        P T+    T  
Sbjct: 2863 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2922

Query: 654  EFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLF-----SSILPSTRASVHLLKSTSDA 708
               + + + +++  +++++  P P P+ +Q+         +++ P+   +     +T+  
Sbjct: 2923 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2982

Query: 709  STPWSSSPSPLPVSLTTSTSAPLSVSQT--------------TLPQSSSTPVLPRARETP 754
            +T  + +P+P P    T T+ P++ + T              T P +++T V P    T 
Sbjct: 2983 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3042

Query: 755  VTSFQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSP 814
              +  T+ +T+  T+  +      ++ +T       T + +P+     T +T  +TT + 
Sbjct: 3043 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3102

Query: 815  LPPSLTESSTE--QTLPATSTNLAQMSPTFTTTILKTSQPLMTT-----PGTLSSTASLV 867
            + P+ T + T+   T P T+T     +PT T T   T+ P+ TT       T + T +  
Sbjct: 3103 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3162

Query: 868  TGPIAVQTT-------AGKQLSLTHP---EILVPQISTEGGISTERNRVIVDATTGLIPL 917
            T PI   TT        G Q   T P      V    T  G  T     I   TT  +  
Sbjct: 3163 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--VTP 3220

Query: 918  TSVPTSAK-EMTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSATFAVQSSTQS 976
            T  PT  +   TT +  T   +P     GT  +P TT ++T   + P       Q+ T +
Sbjct: 3221 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTT 3279

Query: 977  PTTVSSSAS 985
            P T +++ +
Sbjct: 3280 PITTTTTVT 3288



 Score = 90.9 bits (224), Expect = 8e-18
 Identities = 151/789 (19%), Positives = 294/789 (37%), Gaps = 81/789 (10%)

Query: 254  TTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASSPLLDLSSSSESTEKLN 313
            TT+  +P+  P       TTP     +  P  +      T   +P     +++ +     
Sbjct: 2662 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-----PTGTQTPTTTPITTTTTVTPTP 2716

Query: 314  NSTGLQSSSVSQ-TKTMHVATVFTDGGPRT------LRSLTVSLGPVSKTEGFPKDSRIA 366
              TG Q+ + +  T T  V    T  G +T        + TV+  P       P  + I 
Sbjct: 2717 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2776

Query: 367  TTSSSV-------LLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQNDSPTF 419
            TT++           +P+       + VT  P       P+T     +T+      +PT 
Sbjct: 2777 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP---ITTTTTVTPTPT- 2832

Query: 420  GEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADVTGSSASYPEG 479
                  + ++    +P++ T TV+ +  P      T   + T +T +   T      P G
Sbjct: 2833 -----PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTG 2881

Query: 480  VNASVLTQFSDSTVQSGGSHTALGDRSYSESSSTSSSESLNSSAPRGERSIAGISYGQVR 539
                  T  + +T  +  + T  G ++ + +  T+++    +  P G ++          
Sbjct: 2882 TQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2940

Query: 540  GTAIEQRTSSDHTDHTYLSSTFTKGERALLSITDNSSSSDIVESSTSYIKISNSSHSEYS 599
                    +   T  T   +T T            + ++  + ++T+       + ++  
Sbjct: 2941 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3000

Query: 600  SFFHAQTERSNISSYDGEYAQPSTESPVLHTSNL-PSYTPT-----INMPNTSVVLDTDA 653
            +     T  +   +      Q  T +P+  T+ + P+ TPT        P T+    T  
Sbjct: 3001 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3060

Query: 654  EFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLF-----SSILPSTRASVHLLKSTSDA 708
               + + + +++  +++++  P P P+ +Q+         +++ P+   +     +T+  
Sbjct: 3061 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3120

Query: 709  STPWSSSPSPLPVSLTTSTSAPLSVSQT--------------TLPQSSSTPVLPRARETP 754
            +T  + +P+P P    T T+ P++ + T              T P +++T V P    T 
Sbjct: 3121 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3180

Query: 755  VTSFQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSP 814
              +  T+ +T+  T+  +      ++ +T       T + +P+     T +T  +TT + 
Sbjct: 3181 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3240

Query: 815  LPPSLTESSTE--QTLPATSTNLAQMSPTFTTTILKTSQPLMTT-----PGTLSSTASLV 867
            + P+ T + T+   T P T+T     +PT T T   T+ P+ TT       T + T +  
Sbjct: 3241 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3300

Query: 868  TGPIAVQTT-------AGKQLSLTHP---EILVPQISTEGGISTERNRVIVDATTGLIPL 917
            T PI   TT        G Q   T P      V    T  G  T     I   TT  +  
Sbjct: 3301 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--VTP 3358

Query: 918  TSVPTSAK-EMTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSATFAVQSSTQS 976
            T  PT  +   TT +  T   +P     GT  +P TT ++T   + P       Q+ T +
Sbjct: 3359 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTT 3417

Query: 977  PTTVSSSAS 985
            P T +++ +
Sbjct: 3418 PITTTTTVT 3426



 Score = 90.9 bits (224), Expect = 8e-18
 Identities = 151/789 (19%), Positives = 294/789 (37%), Gaps = 81/789 (10%)

Query: 254  TTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASSPLLDLSSSSESTEKLN 313
            TT+  +P+  P       TTP     +  P  +      T   +P     +++ +     
Sbjct: 2800 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-----PTGTQTPTTTPITTTTTVTPTP 2854

Query: 314  NSTGLQSSSVSQ-TKTMHVATVFTDGGPRT------LRSLTVSLGPVSKTEGFPKDSRIA 366
              TG Q+ + +  T T  V    T  G +T        + TV+  P       P  + I 
Sbjct: 2855 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2914

Query: 367  TTSSSV-------LLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQNDSPTF 419
            TT++           +P+       + VT  P       P+T     +T+      +PT 
Sbjct: 2915 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP---ITTTTTVTPTPT- 2970

Query: 420  GEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADVTGSSASYPEG 479
                  + ++    +P++ T TV+ +  P      T   + T +T +   T      P G
Sbjct: 2971 -----PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTG 3019

Query: 480  VNASVLTQFSDSTVQSGGSHTALGDRSYSESSSTSSSESLNSSAPRGERSIAGISYGQVR 539
                  T  + +T  +  + T  G ++ + +  T+++    +  P G ++          
Sbjct: 3020 TQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3078

Query: 540  GTAIEQRTSSDHTDHTYLSSTFTKGERALLSITDNSSSSDIVESSTSYIKISNSSHSEYS 599
                    +   T  T   +T T            + ++  + ++T+       + ++  
Sbjct: 3079 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3138

Query: 600  SFFHAQTERSNISSYDGEYAQPSTESPVLHTSNL-PSYTPT-----INMPNTSVVLDTDA 653
            +     T  +   +      Q  T +P+  T+ + P+ TPT        P T+    T  
Sbjct: 3139 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3198

Query: 654  EFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLF-----SSILPSTRASVHLLKSTSDA 708
               + + + +++  +++++  P P P+ +Q+         +++ P+   +     +T+  
Sbjct: 3199 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3258

Query: 709  STPWSSSPSPLPVSLTTSTSAPLSVSQT--------------TLPQSSSTPVLPRARETP 754
            +T  + +P+P P    T T+ P++ + T              T P +++T V P    T 
Sbjct: 3259 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3318

Query: 755  VTSFQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSP 814
              +  T+ +T+  T+  +      ++ +T       T + +P+     T +T  +TT + 
Sbjct: 3319 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3378

Query: 815  LPPSLTESSTE--QTLPATSTNLAQMSPTFTTTILKTSQPLMTT-----PGTLSSTASLV 867
            + P+ T + T+   T P T+T     +PT T T   T+ P+ TT       T + T +  
Sbjct: 3379 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3438

Query: 868  TGPIAVQTT-------AGKQLSLTHP---EILVPQISTEGGISTERNRVIVDATTGLIPL 917
            T PI   TT        G Q   T P      V    T  G  T     I   TT  +  
Sbjct: 3439 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--VTP 3496

Query: 918  TSVPTSAK-EMTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSATFAVQSSTQS 976
            T  PT  +   TT +  T   +P     GT  +P TT ++T   + P       Q+ T +
Sbjct: 3497 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTT 3555

Query: 977  PTTVSSSAS 985
            P T +++ +
Sbjct: 3556 PITTTTTVT 3564



 Score = 90.9 bits (224), Expect = 8e-18
 Identities = 151/789 (19%), Positives = 294/789 (37%), Gaps = 81/789 (10%)

Query: 254  TTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASSPLLDLSSSSESTEKLN 313
            TT+  +P+  P       TTP     +  P  +      T   +P     +++ +     
Sbjct: 2938 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-----PTGTQTPTTTPITTTTTVTPTP 2992

Query: 314  NSTGLQSSSVSQ-TKTMHVATVFTDGGPRT------LRSLTVSLGPVSKTEGFPKDSRIA 366
              TG Q+ + +  T T  V    T  G +T        + TV+  P       P  + I 
Sbjct: 2993 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3052

Query: 367  TTSSSV-------LLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQNDSPTF 419
            TT++           +P+       + VT  P       P+T     +T+      +PT 
Sbjct: 3053 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP---ITTTTTVTPTPT- 3108

Query: 420  GEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADVTGSSASYPEG 479
                  + ++    +P++ T TV+ +  P      T   + T +T +   T      P G
Sbjct: 3109 -----PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTG 3157

Query: 480  VNASVLTQFSDSTVQSGGSHTALGDRSYSESSSTSSSESLNSSAPRGERSIAGISYGQVR 539
                  T  + +T  +  + T  G ++ + +  T+++    +  P G ++          
Sbjct: 3158 TQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3216

Query: 540  GTAIEQRTSSDHTDHTYLSSTFTKGERALLSITDNSSSSDIVESSTSYIKISNSSHSEYS 599
                    +   T  T   +T T            + ++  + ++T+       + ++  
Sbjct: 3217 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3276

Query: 600  SFFHAQTERSNISSYDGEYAQPSTESPVLHTSNL-PSYTPT-----INMPNTSVVLDTDA 653
            +     T  +   +      Q  T +P+  T+ + P+ TPT        P T+    T  
Sbjct: 3277 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3336

Query: 654  EFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLF-----SSILPSTRASVHLLKSTSDA 708
               + + + +++  +++++  P P P+ +Q+         +++ P+   +     +T+  
Sbjct: 3337 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3396

Query: 709  STPWSSSPSPLPVSLTTSTSAPLSVSQT--------------TLPQSSSTPVLPRARETP 754
            +T  + +P+P P    T T+ P++ + T              T P +++T V P    T 
Sbjct: 3397 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3456

Query: 755  VTSFQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSP 814
              +  T+ +T+  T+  +      ++ +T       T + +P+     T +T  +TT + 
Sbjct: 3457 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3516

Query: 815  LPPSLTESSTE--QTLPATSTNLAQMSPTFTTTILKTSQPLMTT-----PGTLSSTASLV 867
            + P+ T + T+   T P T+T     +PT T T   T+ P+ TT       T + T +  
Sbjct: 3517 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3576

Query: 868  TGPIAVQTT-------AGKQLSLTHP---EILVPQISTEGGISTERNRVIVDATTGLIPL 917
            T PI   TT        G Q   T P      V    T  G  T     I   TT  +  
Sbjct: 3577 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--VTP 3634

Query: 918  TSVPTSAK-EMTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSATFAVQSSTQS 976
            T  PT  +   TT +  T   +P     GT  +P TT ++T   + P       Q+ T +
Sbjct: 3635 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTT 3693

Query: 977  PTTVSSSAS 985
            P T +++ +
Sbjct: 3694 PITTTTTVT 3702



 Score = 90.9 bits (224), Expect = 8e-18
 Identities = 151/789 (19%), Positives = 294/789 (37%), Gaps = 81/789 (10%)

Query: 254  TTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASSPLLDLSSSSESTEKLN 313
            TT+  +P+  P       TTP     +  P  +      T   +P     +++ +     
Sbjct: 3076 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-----PTGTQTPTTTPITTTTTVTPTP 3130

Query: 314  NSTGLQSSSVSQ-TKTMHVATVFTDGGPRT------LRSLTVSLGPVSKTEGFPKDSRIA 366
              TG Q+ + +  T T  V    T  G +T        + TV+  P       P  + I 
Sbjct: 3131 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3190

Query: 367  TTSSSV-------LLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQNDSPTF 419
            TT++           +P+       + VT  P       P+T     +T+      +PT 
Sbjct: 3191 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP---ITTTTTVTPTPT- 3246

Query: 420  GEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADVTGSSASYPEG 479
                  + ++    +P++ T TV+ +  P      T   + T +T +   T      P G
Sbjct: 3247 -----PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTG 3295

Query: 480  VNASVLTQFSDSTVQSGGSHTALGDRSYSESSSTSSSESLNSSAPRGERSIAGISYGQVR 539
                  T  + +T  +  + T  G ++ + +  T+++    +  P G ++          
Sbjct: 3296 TQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3354

Query: 540  GTAIEQRTSSDHTDHTYLSSTFTKGERALLSITDNSSSSDIVESSTSYIKISNSSHSEYS 599
                    +   T  T   +T T            + ++  + ++T+       + ++  
Sbjct: 3355 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3414

Query: 600  SFFHAQTERSNISSYDGEYAQPSTESPVLHTSNL-PSYTPT-----INMPNTSVVLDTDA 653
            +     T  +   +      Q  T +P+  T+ + P+ TPT        P T+    T  
Sbjct: 3415 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3474

Query: 654  EFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLF-----SSILPSTRASVHLLKSTSDA 708
               + + + +++  +++++  P P P+ +Q+         +++ P+   +     +T+  
Sbjct: 3475 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3534

Query: 709  STPWSSSPSPLPVSLTTSTSAPLSVSQT--------------TLPQSSSTPVLPRARETP 754
            +T  + +P+P P    T T+ P++ + T              T P +++T V P    T 
Sbjct: 3535 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3594

Query: 755  VTSFQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSP 814
              +  T+ +T+  T+  +      ++ +T       T + +P+     T +T  +TT + 
Sbjct: 3595 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3654

Query: 815  LPPSLTESSTE--QTLPATSTNLAQMSPTFTTTILKTSQPLMTT-----PGTLSSTASLV 867
            + P+ T + T+   T P T+T     +PT T T   T+ P+ TT       T + T +  
Sbjct: 3655 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3714

Query: 868  TGPIAVQTT-------AGKQLSLTHP---EILVPQISTEGGISTERNRVIVDATTGLIPL 917
            T PI   TT        G Q   T P      V    T  G  T     I   TT  +  
Sbjct: 3715 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--VTP 3772

Query: 918  TSVPTSAK-EMTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSATFAVQSSTQS 976
            T  PT  +   TT +  T   +P     GT  +P TT ++T   + P       Q+ T +
Sbjct: 3773 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTT 3831

Query: 977  PTTVSSSAS 985
            P T +++ +
Sbjct: 3832 PITTTTTVT 3840



 Score = 90.9 bits (224), Expect = 8e-18
 Identities = 151/789 (19%), Positives = 294/789 (37%), Gaps = 81/789 (10%)

Query: 254  TTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASSPLLDLSSSSESTEKLN 313
            TT+  +P+  P       TTP     +  P  +      T   +P     +++ +     
Sbjct: 3214 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-----PTGTQTPTTTPITTTTTVTPTP 3268

Query: 314  NSTGLQSSSVSQ-TKTMHVATVFTDGGPRT------LRSLTVSLGPVSKTEGFPKDSRIA 366
              TG Q+ + +  T T  V    T  G +T        + TV+  P       P  + I 
Sbjct: 3269 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3328

Query: 367  TTSSSV-------LLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQNDSPTF 419
            TT++           +P+       + VT  P       P+T     +T+      +PT 
Sbjct: 3329 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP---ITTTTTVTPTPT- 3384

Query: 420  GEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADVTGSSASYPEG 479
                  + ++    +P++ T TV+ +  P      T   + T +T +   T      P G
Sbjct: 3385 -----PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTG 3433

Query: 480  VNASVLTQFSDSTVQSGGSHTALGDRSYSESSSTSSSESLNSSAPRGERSIAGISYGQVR 539
                  T  + +T  +  + T  G ++ + +  T+++    +  P G ++          
Sbjct: 3434 TQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3492

Query: 540  GTAIEQRTSSDHTDHTYLSSTFTKGERALLSITDNSSSSDIVESSTSYIKISNSSHSEYS 599
                    +   T  T   +T T            + ++  + ++T+       + ++  
Sbjct: 3493 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3552

Query: 600  SFFHAQTERSNISSYDGEYAQPSTESPVLHTSNL-PSYTPT-----INMPNTSVVLDTDA 653
            +     T  +   +      Q  T +P+  T+ + P+ TPT        P T+    T  
Sbjct: 3553 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3612

Query: 654  EFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLF-----SSILPSTRASVHLLKSTSDA 708
               + + + +++  +++++  P P P+ +Q+         +++ P+   +     +T+  
Sbjct: 3613 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3672

Query: 709  STPWSSSPSPLPVSLTTSTSAPLSVSQT--------------TLPQSSSTPVLPRARETP 754
            +T  + +P+P P    T T+ P++ + T              T P +++T V P    T 
Sbjct: 3673 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3732

Query: 755  VTSFQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSP 814
              +  T+ +T+  T+  +      ++ +T       T + +P+     T +T  +TT + 
Sbjct: 3733 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3792

Query: 815  LPPSLTESSTE--QTLPATSTNLAQMSPTFTTTILKTSQPLMTT-----PGTLSSTASLV 867
            + P+ T + T+   T P T+T     +PT T T   T+ P+ TT       T + T +  
Sbjct: 3793 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3852

Query: 868  TGPIAVQTT-------AGKQLSLTHP---EILVPQISTEGGISTERNRVIVDATTGLIPL 917
            T PI   TT        G Q   T P      V    T  G  T     I   TT  +  
Sbjct: 3853 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--VTP 3910

Query: 918  TSVPTSAK-EMTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSATFAVQSSTQS 976
            T  PT  +   TT +  T   +P     GT  +P TT ++T   + P       Q+ T +
Sbjct: 3911 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTT 3969

Query: 977  PTTVSSSAS 985
            P T +++ +
Sbjct: 3970 PITTTTTVT 3978



 Score = 90.9 bits (224), Expect = 8e-18
 Identities = 151/789 (19%), Positives = 294/789 (37%), Gaps = 81/789 (10%)

Query: 254  TTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASSPLLDLSSSSESTEKLN 313
            TT+  +P+  P       TTP     +  P  +      T   +P     +++ +     
Sbjct: 3352 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-----PTGTQTPTTTPITTTTTVTPTP 3406

Query: 314  NSTGLQSSSVSQ-TKTMHVATVFTDGGPRT------LRSLTVSLGPVSKTEGFPKDSRIA 366
              TG Q+ + +  T T  V    T  G +T        + TV+  P       P  + I 
Sbjct: 3407 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3466

Query: 367  TTSSSV-------LLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQNDSPTF 419
            TT++           +P+       + VT  P       P+T     +T+      +PT 
Sbjct: 3467 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP---ITTTTTVTPTPT- 3522

Query: 420  GEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADVTGSSASYPEG 479
                  + ++    +P++ T TV+ +  P      T   + T +T +   T      P G
Sbjct: 3523 -----PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTG 3571

Query: 480  VNASVLTQFSDSTVQSGGSHTALGDRSYSESSSTSSSESLNSSAPRGERSIAGISYGQVR 539
                  T  + +T  +  + T  G ++ + +  T+++    +  P G ++          
Sbjct: 3572 TQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3630

Query: 540  GTAIEQRTSSDHTDHTYLSSTFTKGERALLSITDNSSSSDIVESSTSYIKISNSSHSEYS 599
                    +   T  T   +T T            + ++  + ++T+       + ++  
Sbjct: 3631 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3690

Query: 600  SFFHAQTERSNISSYDGEYAQPSTESPVLHTSNL-PSYTPT-----INMPNTSVVLDTDA 653
            +     T  +   +      Q  T +P+  T+ + P+ TPT        P T+    T  
Sbjct: 3691 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3750

Query: 654  EFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLF-----SSILPSTRASVHLLKSTSDA 708
               + + + +++  +++++  P P P+ +Q+         +++ P+   +     +T+  
Sbjct: 3751 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3810

Query: 709  STPWSSSPSPLPVSLTTSTSAPLSVSQT--------------TLPQSSSTPVLPRARETP 754
            +T  + +P+P P    T T+ P++ + T              T P +++T V P    T 
Sbjct: 3811 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3870

Query: 755  VTSFQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSP 814
              +  T+ +T+  T+  +      ++ +T       T + +P+     T +T  +TT + 
Sbjct: 3871 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3930

Query: 815  LPPSLTESSTE--QTLPATSTNLAQMSPTFTTTILKTSQPLMTT-----PGTLSSTASLV 867
            + P+ T + T+   T P T+T     +PT T T   T+ P+ TT       T + T +  
Sbjct: 3931 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3990

Query: 868  TGPIAVQTT-------AGKQLSLTHP---EILVPQISTEGGISTERNRVIVDATTGLIPL 917
            T PI   TT        G Q   T P      V    T  G  T     I   TT  +  
Sbjct: 3991 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--VTP 4048

Query: 918  TSVPTSAK-EMTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSATFAVQSSTQS 976
            T  PT  +   TT +  T   +P     GT  +P TT ++T   + P       Q+ T +
Sbjct: 4049 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTT 4107

Query: 977  PTTVSSSAS 985
            P T +++ +
Sbjct: 4108 PITTTTTVT 4116



 Score = 90.5 bits (223), Expect = 1e-17
 Identities = 92/409 (22%), Positives = 169/409 (41%), Gaps = 46/409 (11%)

Query: 620  QPSTESPVLHTSNL-PSYTPT-----INMPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSG 673
            Q  T +P+  T+ + P+ TPT        P T+    T     + + + +++  +++++ 
Sbjct: 1917 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 1976

Query: 674  PPLPLPSVSQSHHLF-----SSILPSTRASVHLLKSTSDASTPWSSSPSPLPVSLTTSTS 728
             P P P+ +Q+         +++ P+   +     +T+  +T  + +P+P P    T T+
Sbjct: 1977 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2036

Query: 729  APLSVSQT--------------TLPQSSSTPVLPRARETPVTSFQTSTMTSFMTMLHSSQ 774
             P++ + T              T P +++T V P    T   +  T+ +T+  T+  +  
Sbjct: 2037 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2096

Query: 775  TADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESSTE--QTLPATS 832
                ++ +T       T + +P+     T +T  +TT + + P+ T + T+   T P T+
Sbjct: 2097 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2156

Query: 833  TNLAQMSPTFTTTILKTSQPLMTT-----PGTLSSTASLVTGPIAVQTT-------AGKQ 880
            T     +PT T T   T+ P+ TT       T + T +  T PI   TT        G Q
Sbjct: 2157 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2216

Query: 881  LSLTHP---EILVPQISTEGGISTERNRVIVDATTGLIPLTSVPTSAK-EMTTKLGVTAE 936
               T P      V    T  G  T     I   TT  +  T  PT  +   TT +  T  
Sbjct: 2217 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--VTPTPTPTGTQTPTTTPITTTTT 2274

Query: 937  YSPASRSLGTSPSPQTTVVSTAEDLAPKSATFAVQSSTQSPTTVSSSAS 985
             +P     GT  +P TT ++T   + P       Q+ T +P T +++ +
Sbjct: 2275 VTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2322



 Score = 80.1 bits (196), Expect = 1e-14
 Identities = 146/785 (18%), Positives = 290/785 (36%), Gaps = 84/785 (10%)

Query: 254  TTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASSPLLDLSSSSESTEKLN 313
            TT+  +P+  P       TTP     +  P  +      T   +P     +++ +     
Sbjct: 3582 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-----PTGTQTPTTTPITTTTTVTPTP 3636

Query: 314  NSTGLQSSSVSQ-TKTMHVATVFTDGGPRT------LRSLTVSLGPVSKTEGFPKDSRIA 366
              TG Q+ + +  T T  V    T  G +T        + TV+  P       P  + I 
Sbjct: 3637 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3696

Query: 367  TTSSSV-------LLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQNDSPTF 419
            TT++           +P+       + VT  P       P+T     +T+      +PT 
Sbjct: 3697 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP---ITTTTTVTPTPT- 3752

Query: 420  GEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADVTGSSASYPEG 479
                  + ++    +P++ T TV+ +  P      T   + T +T +   T      P G
Sbjct: 3753 -----PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTG 3801

Query: 480  VNASVLTQFSDSTVQSGGSHTALGDRSYSESSSTSSSESLNSSAPRGERSIAGISYGQVR 539
                  T  + +T  +  + T  G ++ + +  T+++    +  P G ++          
Sbjct: 3802 TQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3860

Query: 540  GTAIEQRTSSDHTDHTYLSSTFTKGERALLSITDNSSSSDIVESSTSYIKISNSSHSEYS 599
                    +   T  T   +T T            + ++  + ++T+       + ++  
Sbjct: 3861 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3920

Query: 600  SFFHAQTERSNISSYDGEYAQPSTESPVLHTSNL-PSYTPT-----INMPNTSVVLDTDA 653
            +     T  +   +      Q  T +P+  T+ + P+ TPT        P T+    T  
Sbjct: 3921 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3980

Query: 654  EFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLF-----SSILPSTRASVHLLKSTSDA 708
               + + + +++  +++++  P P P+ +Q+         +++ P+   +     +T+  
Sbjct: 3981 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 4040

Query: 709  STPWSSSPSPLPVSLTTSTSAPLSVSQT--------------TLPQSSSTPVLPRARETP 754
            +T  + +P+P P    T T+ P++ + T              T P +++T V P    T 
Sbjct: 4041 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 4100

Query: 755  VTSFQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSP 814
              +  T+ +T+  T+  +      ++ +T       T + +P+     T +T  +TT + 
Sbjct: 4101 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 4160

Query: 815  LPPSLTESSTE--QTLPATSTNLAQMSPTFTTTILKTSQPLMTTPGTLSSTASLVTGPIA 872
            + P+ T + T+   T P T+T     +PT T T         T P T +STA     PIA
Sbjct: 4161 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT--------QTGPPTHTSTA-----PIA 4207

Query: 873  VQTTAGKQLSLTHPEILVPQISTEGGISTERNRVIVDATTGLIPLTS-VPTSAKEMTTKL 931
              TT+        PE   PQ S         +  ++      I +TS  P S     T  
Sbjct: 4208 ELTTSNPP-----PESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTT 4262

Query: 932  GVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSATFAVQSS---TQSPTTVSSSASVNS 988
                  SP   +  + P   T   +T    AP  +T    ++   T +PT +S+ + + +
Sbjct: 4263 SGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRT 4322

Query: 989  CAVNP 993
              + P
Sbjct: 4323 TGLRP 4327



 Score = 77.4 bits (189), Expect = 9e-14
 Identities = 87/366 (23%), Positives = 147/366 (40%), Gaps = 36/366 (9%)

Query: 622  STESPVLHTSNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSV 681
            +T SP   T+  P  T T + P T+          S   S++++   +++  PP   PS 
Sbjct: 1420 TTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSP 1479

Query: 682  SQSHHLFSSILPSTRASVHLLKSTSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQS 741
                       P+T  S     +T+   T   S P+  P++   ST+     +  + P +
Sbjct: 1480 -----------PTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTT 1528

Query: 742  SSTPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSL 801
            ++T   P    +P T+   +  TS  T+  ++  +   + +T       T + SP   + 
Sbjct: 1529 TTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPP---TTTPSPPTTTT 1585

Query: 802  PTESTKAVTT----NSPLPPSLTESSTEQTL-PATSTNLAQMSPTFTTTILKTSQPLMTT 856
            P+  T   TT     +P PP+ T ++   T  P+  T      PT TTT+  T+ P  + 
Sbjct: 1586 PSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTP--SP 1643

Query: 857  PGTLSSTASLVTGPIAVQTTAGKQLSLTHPEILVPQISTEGGISTERNRVIVDATTGLIP 916
            P T ++T    T P    TT         P   +   +T    +T  + +    TT   P
Sbjct: 1644 PPTTTTTPPPTTTPSPPTTTT--------PSPPITTTTTPPPTTTPSSPI---TTTPSPP 1692

Query: 917  LTSVPTSAKEMTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSATFAVQSSTQS 976
             T++ T +   T    +T   +P+S    T+PSP  T ++T       S       +T  
Sbjct: 1693 TTTMTTPSPTTTPSSPITTTTTPSST---TTPSPPPTTMTTPSPTTTPSPP-TTTMTTLP 1748

Query: 977  PTTVSS 982
            PTT SS
Sbjct: 1749 PTTTSS 1754



 Score = 75.1 bits (183), Expect = 4e-13
 Identities = 136/692 (19%), Positives = 265/692 (38%), Gaps = 68/692 (9%)

Query: 254  TTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASSPLLDLSSSSESTEKLN 313
            TT+  +P+  P       TTP     +  P  +      T   +P     +++ +     
Sbjct: 3674 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-----PTGTQTPTTTPITTTTTVTPTP 3728

Query: 314  NSTGLQSSSVSQ-TKTMHVATVFTDGGPRT------LRSLTVSLGPVSKTEGFPKDSRIA 366
              TG Q+ + +  T T  V    T  G +T        + TV+  P       P  + I 
Sbjct: 3729 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3788

Query: 367  TTSSSV-------LLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQNDSPTF 419
            TT++           +P+       + VT  P       P+T     +T+      +PT 
Sbjct: 3789 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP---ITTTTTVTPTPT- 3844

Query: 420  GEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADVTGSSASYPEG 479
                  + ++    +P++ T TV+ +  P      T   + T +T +   T      P G
Sbjct: 3845 -----PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTG 3893

Query: 480  VNASVLTQFSDSTVQSGGSHTALGDRSYSESSSTSSSESLNSSAPRGERSIAGISYGQVR 539
                  T  + +T  +  + T  G ++ + +  T+++    +  P G ++          
Sbjct: 3894 TQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3952

Query: 540  GTAIEQRTSSDHTDHTYLSSTFTKGERALLSITDNSSSSDIVESSTSYIKISNSSHSEYS 599
                    +   T  T   +T T            + ++  + ++T+       + ++  
Sbjct: 3953 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 4012

Query: 600  SFFHAQTERSNISSYDGEYAQPSTESPVLHTSNL-PSYTPT-----INMPNTSVVLDTDA 653
            +     T  +   +      Q  T +P+  T+ + P+ TPT        P T+    T  
Sbjct: 4013 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 4072

Query: 654  EFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLF-----SSILPSTRASVHLLKSTSDA 708
               + + + +++  +++++  P P P+ +Q+         +++ P+   +     +T+  
Sbjct: 4073 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 4132

Query: 709  STPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQSS--------STPVLPRARETPVTSFQT 760
            +T  + +P+P P    T T+ P++ + T  P  +        +TP+      TP T   T
Sbjct: 4133 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPT 4191

Query: 761  STMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLT 820
             T T   T   ++  A+L + + P +      S+S S  S  TEST  ++T   LPP++ 
Sbjct: 4192 GTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTS--SPLTESTTLLST---LPPAIE 4246

Query: 821  ESST----EQTLPATSTNLAQMSPTFTTTILKTSQPLMTTPGTLSSTASLVTGPIAVQTT 876
             +ST      T P T++    +SP  +TT   TS P   T GT + ++S  T P  VQTT
Sbjct: 4247 MTSTAPPSTPTAPTTTSGGHTLSPPPSTT---TSPPGTPTRGTTTGSSSAPT-PSTVQTT 4302

Query: 877  AGKQLSLTHPEILVPQISTEGGISTERNRVIV 908
                 + T   +  P I    G+    + V++
Sbjct: 4303 TTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLI 4334



 Score = 73.9 bits (180), Expect = 1e-12
 Identities = 92/381 (24%), Positives = 141/381 (37%), Gaps = 37/381 (9%)

Query: 622  STESPVLHTSNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSV 681
            +T SP   T + P  + T   P T+    T        +++ S   +++++ PP   PS 
Sbjct: 1397 TTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSP 1456

Query: 682  SQSHHLFSSILPSTRASVHLLKSTSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQS 741
              S         +T         +   +TP   + +P P + TT+T  P     TT    
Sbjct: 1457 PIS---------TTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPT----TTPSPP 1503

Query: 742  SSTPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSL 801
            ++TP+ P A  T +    T +  +  T      T      +TP      T +  P+    
Sbjct: 1504 TTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTT--- 1560

Query: 802  PTESTKAVTTNSPLPPSLTESSTEQTLPATSTNLAQMSPTFTT----TILKTSQPLMTTP 857
             T S    TT +P PP+ T S    T P+  T      P  TT    T   T+ P  TTP
Sbjct: 1561 -TPSPPPTTTTTP-PPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTP 1618

Query: 858  GTLSST-----ASLVTGPIAVQTTAGKQLSLTHPEILVPQISTEGGISTERNRVIVDATT 912
               ++T      S  T P     +     + T P    P   T    +T  +  I   TT
Sbjct: 1619 SPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPT----TTTPSPPITTTTT 1674

Query: 913  GLIPLTSVPTSAKEMTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSATFAVQS 972
               P T+ P+S    T     T   +P+  +  +SP   TT  S+    +P   T     
Sbjct: 1675 P--PPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTM---- 1728

Query: 973  STQSPTTVSSSASVNSCAVNP 993
            +T SPTT  S  +     + P
Sbjct: 1729 TTPSPTTTPSPPTTTMTTLPP 1749



 Score = 71.6 bits (174), Expect = 5e-12
 Identities = 70/269 (26%), Positives = 107/269 (39%), Gaps = 25/269 (9%)

Query: 733  VSQTTLPQSSSTPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITE 792
            V+Q T   +++T        TP+T+  T T T   T   +  T  + + +T      +T 
Sbjct: 1879 VTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT------VTP 1932

Query: 793  SKSPSLVSLPTESTKAVTTNSPLPPSLTESSTEQTLPATSTNLAQMSPTFTTTILKTSQP 852
            + +P+    PT +    TT     P+ T + T  T P T+T     +PT T T   T+ P
Sbjct: 1933 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 1992

Query: 853  LMTT-----PGTLSSTASLVTGPIAVQTT-------AGKQLSLTHP---EILVPQISTEG 897
            + TT       T + T +  T PI   TT        G Q   T P      V    T  
Sbjct: 1993 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2052

Query: 898  GISTERNRVIVDATTGLIPLTSVPTSAK-EMTTKLGVTAEYSPASRSLGTSPSPQTTVVS 956
            G  T     I   TT  +  T  PT  +   TT +  T   +P     GT  +P TT ++
Sbjct: 2053 GTQTPTTTPITTTTT--VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPIT 2109

Query: 957  TAEDLAPKSATFAVQSSTQSPTTVSSSAS 985
            T   + P       Q+ T +P T +++ +
Sbjct: 2110 TTTTVTPTPTPTGTQTPTTTPITTTTTVT 2138



 Score = 68.9 bits (167), Expect = 3e-11
 Identities = 96/410 (23%), Positives = 150/410 (36%), Gaps = 61/410 (14%)

Query: 622  STESPVLHTSNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSV 681
            +T SP   T+  P  T T + P T+          +   +++ S  +++++ PP   P+ 
Sbjct: 1560 TTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPP---PTT 1616

Query: 682  SQSHHLFSSILPSTRASVHLLKSTSDASTPWSSSPSPLPVSL----TTSTSAPLSVSQTT 737
            + S    + I P T  S   L  T+  S P +++ +P P +     TT+T +P  ++ TT
Sbjct: 1617 TPSPPTTTPITPPT--STTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSP-PITTTT 1673

Query: 738  LPQSSSTPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPS 797
             P  ++TP  P    TP     T T  S  T   S  T      ST       T   +PS
Sbjct: 1674 TPPPTTTPSSP-ITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPS 1732

Query: 798  LVSLPTESTKAVTTNSPLPPSLTESSTEQTLPATSTNLAQMSPTFTTTILKTSQPLMTTP 857
              + P+  T  +TT   LPP+ T S    T    S      SP  TTT      PL    
Sbjct: 1733 PTTTPSPPTTTMTT---LPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTPCVPLCNWT 1789

Query: 858  GTLSSTASLVTGP------IAVQTTAGKQLSLTHPEILVPQISTEGGISTERNRVIVDAT 911
            G L S       P      I      G   +++    + P +     I      V+ D +
Sbjct: 1790 GWLDSGKPNFHKPGGDTELIGDVCGPGWAANISCRATMYPDVP----IGQLGQTVVCDVS 1845

Query: 912  TGLI--------------------------------PLTSVPTSAKE----MTTKLGVTA 935
             GLI                                P T   T+ +      TT +  T 
Sbjct: 1846 VGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPPTTTPITTTT 1905

Query: 936  EYSPASRSLGTSPSPQTTVVSTAEDLAPKSATFAVQSSTQSPTTVSSSAS 985
              +P     GT  +P TT ++T   + P       Q+ T +P T +++ +
Sbjct: 1906 TVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 1954



 Score = 63.9 bits (154), Expect = 1e-09
 Identities = 73/294 (24%), Positives = 123/294 (41%), Gaps = 36/294 (12%)

Query: 622  STESPVLHTSNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSV 681
            +T SP   T+  P  T T + P T+ +    +      +++ S  ++++++ PP   PS 
Sbjct: 1482 TTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSP 1541

Query: 682  SQSHHLFSSILPSTRASVHLLKSTSDASTPWSSSPSPLPVSL----TTSTSAPLSVSQTT 737
              +    + I P T  S   L  T+  S P +++ +P P +     TT+T +P +++ TT
Sbjct: 1542 PTT----TPITPPT--STTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTT 1595

Query: 738  LPQSSSTPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPS 797
             P  ++TP  P    T      T +  +   +   + T  L   +TP      T +  P+
Sbjct: 1596 -PPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPT 1654

Query: 798  LV-SLPTESTKA--VTTNSPLPPSLTESSTEQTLPAT-STNLAQMSPTFTT--------- 844
               S PT +T +  +TT +  PP+ T SS   T P+  +T +   SPT T          
Sbjct: 1655 TTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTT 1714

Query: 845  -----------TILKTSQPLMT-TPGTLSSTASLVTGPIAVQTTAGKQLSLTHP 886
                       T + T  P  T +P T + T    T   +  TT     S+T P
Sbjct: 1715 PSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPP 1768



 Score = 61.2 bits (147), Expect = 6e-09
 Identities = 63/245 (25%), Positives = 101/245 (41%), Gaps = 33/245 (13%)

Query: 621  PSTESPVL---HTSNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPP-- 675
            P T +P+     T+ LP  T T + P T+          S  ++++ S  + +++ PP  
Sbjct: 1541 PPTTTPITPPTSTTTLPP-TTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPT 1599

Query: 676  -LPLPSVSQSHHLFSSILPSTRASVHLLKSTSDASTPWSSSPSPLPVSLTTS--TSAPLS 732
              P P  + +     +  PS   +  +   TS  + P +++PSP P + TT   T+ P  
Sbjct: 1600 TTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSP 1659

Query: 733  VSQTTLPQSSSTPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITE 792
             + TT     +T   P    TP +   T+      TM   S T    + S+P     IT 
Sbjct: 1660 PTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTT---TPSSP-----ITT 1711

Query: 793  SKSPSLVSLPTESTKAVTTNSPLPPSLTESSTEQTLPATSTNLAQMSPTFTTTILKTSQP 852
            + +PS  + P+     +TT SP       ++T  TLP T+T                S P
Sbjct: 1712 TTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTT----------------SSP 1755

Query: 853  LMTTP 857
            L TTP
Sbjct: 1756 LTTTP 1760


>gi|239749213 PREDICTED: mucin 3B, cell surface associated, partial
            [Homo sapiens]
          Length = 1063

 Score = 95.5 bits (236), Expect = 3e-19
 Identities = 174/782 (22%), Positives = 296/782 (37%), Gaps = 81/782 (10%)

Query: 293  TAASSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGP 352
            T+ S+P    +SS  +TE  +  T   +SS++ T+T+  +T        T  SL  +   
Sbjct: 5    TSRSTP--GFTSSIVTTETTSPHTPGFTSSITTTETIPHSTP-------TFTSLITTSEM 55

Query: 353  VSKTEGFPKDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSLRW 412
             S +   P  +   TT+ S   SP +  S   S  + +     F    T NE   TS   
Sbjct: 56   TSHST--PSLTFSITTTKSTSYSPPSFTSSITSTESTSHSTPPFTSSITTNE--TTSHST 111

Query: 413  QNDSPTFGEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADVTG- 471
             + + +  + +  S S     S  S T++ S S  P            T+S T+ ++T  
Sbjct: 112  PSFTTSITKTKTTSHSTPSFTSSNSITDSRSHSTPPF-----------TSSVTTPEMTSH 160

Query: 472  SSASYPEGVNASVLTQFSDSTVQSGGSHTALGDRSYSESSSTSSSESLNSSAPRGERSIA 531
            ++ S+   +  +  T  S  +  S   H+ +   + + +S  +++E+  +S P    S++
Sbjct: 161  NTPSFMSSIITTETTSHSTPSFTSSTIHSTVSSSTTAITSPFTTAETGVTSTPSSPSSLS 220

Query: 532  -GISYGQVRG-TAIEQRTSSDHTDHTYLSSTFTKGERALLSITDNSSSSDIVESSTSYIK 589
              I    +R  T +   TS+  T  T L S  T        I   SSS  I  + TS + 
Sbjct: 221  TDIPTTSLRTLTPLSLSTSTSLTTTTDLPSIPTDISSLPTPIHIISSSPSIQSTETSSLV 280

Query: 590  ISNSSHSEYSSFFHAQTERSNISSYDGEYA----QPSTESPVLHTSNLPSYTPTINMPNT 645
             + S            TE + ISS+          P+T++P +  S   + T T  +P T
Sbjct: 281  GTTSPTMSTVRATLRSTENTPISSFSTSIVVTPETPTTQAPPVLMS--ATGTQTSPVPTT 338

Query: 646  SVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSILPSTRASVHLLKST 705
                  D+   +  + + S++ S   S    P+PS   S    +  +PS + S   L ST
Sbjct: 339  VTFGSMDSSTSTLHTLTPSTALSKIMSTSQFPIPSTHSSTLQTTPSIPSLQTS---LTST 395

Query: 706  SDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQSSSTPVLPRARETPVTSFQTSTMTS 765
            S+ +T   +  S    ++ TS S  +  S  T+  SSS      A  TPV +    ++ S
Sbjct: 396  SEFTTESFTRGSTSTNAILTSFSTIIWSSTPTIIMSSSPS---SASITPVFATTIHSVPS 452

Query: 766  FMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTK-------AVTTNSPLPPS 818
               +  +         + P      T S SP+  SL T  T+       ++ + +P P +
Sbjct: 453  SPYIFSTENVGSASITAFPSLSSSSTTSTSPTSSSLTTALTEITPFSYISLPSTTPCPGT 512

Query: 819  LT-----ESSTEQTLPATSTNLAQMSPTFTTTILKTSQPLMTTPGTLSSTASLVTGPIAV 873
            +T      S T+  +    +  A   PT   T+   +  ++T P ++S   +L T     
Sbjct: 513  ITITIVPASPTDPCVEMDPSTEATSPPTTPLTVFPFTTEMVTCPSSISMQTTLATHMDTS 572

Query: 874  QTTAGKQLSLTHPEILVPQISTEGGISTERNRVIVDAT-----------TGLIPLTSVPT 922
              T   + S+      +P  S+  G  T     +  +T             +IP      
Sbjct: 573  SMTPESESSI------IPNASSSTGTGTVPTNTVFTSTRLPTSETWLSNNSVIPTPLPGV 626

Query: 923  SAKEMTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSATFAVQSSTQSPTTVSS 982
            S   +T K   +      + S  T PSP T   S       ++ T      T   T+  +
Sbjct: 627  STIPLTMKPSSSLPTILRTSSKSTHPSPPTARTSETSVATTQTPTTLTTRRTTPITSWMT 686

Query: 983  SASVNSCAVNPCLHNGECVADNTSRGYHCRCPPSWQGDDCSVDVN-------ECLSNPCP 1035
            + S  +     C + G      T     C C P + GD C +          + L   CP
Sbjct: 687  TQSTLTTTAGTCDNGG------TWEQGQCACLPGFSGDRCQLQTRCQNGGQWDGLKCQCP 740

Query: 1036 ST 1037
            ST
Sbjct: 741  ST 742



 Score = 81.6 bits (200), Expect = 5e-15
 Identities = 170/733 (23%), Positives = 285/733 (38%), Gaps = 88/733 (12%)

Query: 175 SSSRTNFTI---LPVGYSLEIATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTA 231
           SS  T  TI    P   SL   + +TS S    + S+    S+S        +   S T+
Sbjct: 31  SSITTTETIPHSTPTFTSLITTSEMTSHSTPSLTFSITTTKSTS--------YSPPSFTS 82

Query: 232 SEMGTERAMGLSEEWTVH-SQEATTSAWSPSFLPALEMGELT---TPSRKRNSSGPDLSW 287
           S   TE     +  +T   +   TTS  +PSF  ++   + T   TPS   ++S  D   
Sbjct: 83  SITSTESTSHSTPPFTSSITTNETTSHSTPSFTTSITKTKTTSHSTPSFTSSNSITDS-- 140

Query: 288 LHFYRTAASSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLT 347
               R+ ++ P     ++ E T   +N+    SS ++   T H    FT     T+ S T
Sbjct: 141 ----RSHSTPPFTSSVTTPEMTS--HNTPSFMSSIITTETTSHSTPSFTSS---TIHS-T 190

Query: 348 VSLGPVSKTEGFPKDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGL 407
           VS    + T  F       T  + V  +PS+  S      T +      +  ST      
Sbjct: 191 VSSSTTAITSPF------TTAETGVTSTPSSPSSLSTDIPTTSLRTLTPLSLSTS----- 239

Query: 408 TSLRWQNDSPTFGE---------HQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHW 458
           TSL    D P+            H ++SS  +Q+    S   T S +++ +R     A  
Sbjct: 240 TSLTTTTDLPSIPTDISSLPTPIHIISSSPSIQSTETSSLVGTTSPTMSTVR-----ATL 294

Query: 459 LLTNSTTSADVTGSSASYPEGVNASVLTQFSDSTVQSGGSHTALGDRSYSESSSTSSSES 518
             T +T  +  + S    PE    +  TQ     + + G+ T+    + +  S  SS+ +
Sbjct: 295 RSTENTPISSFSTSIVVTPE----TPTTQAPPVLMSATGTQTSPVPTTVTFGSMDSSTST 350

Query: 519 LNSSAPRGERS-IAGISYGQVRGT--AIEQRTSSDHTDHTYLSST-------FTKGERAL 568
           L++  P    S I   S   +  T  +  Q T S  +  T L+ST       FT+G  + 
Sbjct: 351 LHTLTPSTALSKIMSTSQFPIPSTHSSTLQTTPSIPSLQTSLTSTSEFTTESFTRGSTST 410

Query: 569 LSITDNSSSSDIVESSTSYIKISNSSHSE-----YSSFFHAQTERSNISSYDGEYAQPST 623
            +I   +S S I+ SST  I +S+S  S      +++  H+      I S +   +   T
Sbjct: 411 NAIL--TSFSTIIWSSTPTIIMSSSPSSASITPVFATTIHSVPSSPYIFSTENVGSASIT 468

Query: 624 ESPVLHTSNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPL-PSVS 682
             P L +S+  S +PT +   T++   T   ++S  S++    + + +  P  P  P V 
Sbjct: 469 AFPSLSSSSTTSTSPTSSSLTTALTEITPFSYISLPSTTPCPGTITITIVPASPTDPCVE 528

Query: 683 QSHHLFSSILPSTRASVHLLKSTSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQSS 742
                 ++  P+T  +V           P+++     P S++  T+    +  +++   S
Sbjct: 529 MDPSTEATSPPTTPLTVF----------PFTTEMVTCPSSISMQTTLATHMDTSSMTPES 578

Query: 743 STPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADLKSQSTPHQ---EKVITESKSPSLV 799
            + ++P A  +  T    +      T L +S+T    +   P        I  +  PS  
Sbjct: 579 ESSIIPNASSSTGTGTVPTNTVFTSTRLPTSETWLSNNSVIPTPLPGVSTIPLTMKPSS- 637

Query: 800 SLPTESTKAVTTNSPLPPSLTESSTEQTLPATSTNLAQMSPTFTTTILKTSQPLMTTPGT 859
           SLPT    +  +  P PP+   S T      T T L     T  T+ + T   L TT GT
Sbjct: 638 SLPTILRTSSKSTHPSPPTARTSETSVATTQTPTTLTTRRTTPITSWMTTQSTLTTTAGT 697

Query: 860 LSSTASLVTGPIA 872
             +  +   G  A
Sbjct: 698 CDNGGTWEQGQCA 710



 Score = 80.5 bits (197), Expect = 1e-14
 Identities = 141/607 (23%), Positives = 238/607 (39%), Gaps = 84/607 (13%)

Query: 439 TETVSRSVAPMRGGEITAHW-------LLTNSTTSADVTGSSASYPEGVNASVLTQFSDS 491
           TET SRS        +T            ++ TT+  +  S+ ++   +  S +T  S S
Sbjct: 2   TETTSRSTPGFTSSIVTTETTSPHTPGFTSSITTTETIPHSTPTFTSLITTSEMT--SHS 59

Query: 492 TVQSGGSHTALGDRSYSESSSTSSSESLNSSAPRGERSIAGISYGQVRG-------TAIE 544
           T     S T     SYS  S TSS  S  S++       + I+  +          T+I 
Sbjct: 60  TPSLTFSITTTKSTSYSPPSFTSSITSTESTSHSTPPFTSSITTNETTSHSTPSFTTSIT 119

Query: 545 QRTSSDHTDHTYLSSTFTKGERALLS-------ITDNSSSSDIVESSTSYIKISNSSHSE 597
           +  ++ H+  ++ SS      R+  +        T   +S +     +S I    +SHS 
Sbjct: 120 KTKTTSHSTPSFTSSNSITDSRSHSTPPFTSSVTTPEMTSHNTPSFMSSIITTETTSHST 179

Query: 598 YSSFFHAQTERSNISSYDGEYAQPST--ESPVLHTSNLPSYTPTINMPNTSVVLDTDAEF 655
            S  F + T  S +SS       P T  E+ V  T + PS   T ++P TS+        
Sbjct: 180 PS--FTSSTIHSTVSSSTTAITSPFTTAETGVTSTPSSPSSLST-DIPTTSL------RT 230

Query: 656 VSDSSSSSSSSSSSSSSGPPLP--LPSVSQSHHLFSSILPSTRASVHLLKSTSDASTPWS 713
           ++  S S+S+S ++++  P +P  + S+    H+ SS  PS       ++ST  +S   +
Sbjct: 231 LTPLSLSTSTSLTTTTDLPSIPTDISSLPTPIHIISSS-PS-------IQSTETSSLVGT 282

Query: 714 SSP--SPLPVSLTTSTSAPLSVSQTTLPQSSSTPVLPRARETPVTSFQTSTMTS------ 765
           +SP  S +  +L ++ + P+S   T++     TP  P  +  PV    T T TS      
Sbjct: 283 TSPTMSTVRATLRSTENTPISSFSTSIVV---TPETPTTQAPPVLMSATGTQTSPVPTTV 339

Query: 766 -FMTMLHSSQTADLKSQSTPHQEKVITESKSP----------SLVSLPTESTKAVTTNSP 814
            F +M  S+ T    + ST    K+++ S+ P          +  S+P+  T   +T+  
Sbjct: 340 TFGSMDSSTSTLHTLTPSTA-LSKIMSTSQFPIPSTHSSTLQTTPSIPSLQTSLTSTSEF 398

Query: 815 LPPSLTESSTEQTLPATSTNLAQMSPTFTTTILKTSQPLMTTPGTLSSTASLVTGPIAVQ 874
              S T  ST      TS +    S T T  +  +      TP   ++  S+ + P    
Sbjct: 399 TTESFTRGSTSTNAILTSFSTIIWSSTPTIIMSSSPSSASITPVFATTIHSVPSSPYIFS 458

Query: 875 TTAGKQLSLT-HPEILVPQISTEGGISTERNRVIVDAT-------------TGLIPLTSV 920
           T      S+T  P +     ++    S+     + + T              G I +T V
Sbjct: 459 TENVGSASITAFPSLSSSSTTSTSPTSSSLTTALTEITPFSYISLPSTTPCPGTITITIV 518

Query: 921 PTSAKEMTTKLGVTAE-YSPASRSLGTSPSPQTTVVSTAEDLAPKSATFAVQSSTQSPTT 979
           P S  +   ++  + E  SP +  L  +  P TT + T         T A    T S T 
Sbjct: 519 PASPTDPCVEMDPSTEATSPPTTPL--TVFPFTTEMVTCPSSISMQTTLATHMDTSSMTP 576

Query: 980 VSSSASV 986
            S S+ +
Sbjct: 577 ESESSII 583


>gi|239508973 PREDICTED: similar to Mucin-3A [Homo sapiens]
          Length = 596

 Score = 95.5 bits (236), Expect = 3e-19
 Identities = 131/524 (25%), Positives = 212/524 (40%), Gaps = 77/524 (14%)

Query: 549  SDHTDHTYLSSTFTKGERALLSITDNSSSSDIVESSTSYIKISNSSHSEYSSFFHAQTER 608
            S +T  T  S    K E    ++   S++++ V  ++  I IS+ +     S     T+ 
Sbjct: 97   SSNTSTTPTSKFAFKVETTPPTVLVYSATTECVYPTSFIITISHPT-----SICVTTTQV 151

Query: 609  SNISSYDGEYAQPSTESPVLHTSNLPSYTPT-------INMPNTSVVLDTDAEFVSDSSS 661
            +  SSY    + P T+ PV   ++  S T T        + P+T+   +T    V+ SS 
Sbjct: 152  AFTSSYT---STPVTQKPVTTVTSTYSMTTTEKGTSAMTSSPSTTTARETPIVTVTPSSV 208

Query: 662  SSS--------SSSSSSSSGPPLPLPSVSQSHHLFSSILPSTRASVHLLKSTSDASTPWS 713
            S++        SS++ ++   PLP  S+    H  +S  P        LK+   +++P +
Sbjct: 209  SATDTTFHTTISSTTRTTERTPLPTGSI----HTTTSPTPVFTT----LKTAVTSTSPIT 260

Query: 714  SSPSPLPVSLTTSTSAPLSVSQTTLPQSSSTPVLPRARETPVTSFQTSTMTSFMTMLHSS 773
            SS +    S  T TS   + SQ T   + S+P       TPV S +T T     T   S+
Sbjct: 261  SSIT----STNTVTSMTTTASQPTATNTLSSPTRTILSSTPVLSTETITSGITNTTPLST 316

Query: 774  QTADLK---SQSTPHQEKVI------TESKSPSLVSLPTESTKAVTTNSPLPPSLTESST 824
                L    S+STP  E         T + S + ++  T  T  ++T + LPP      T
Sbjct: 317  LVTTLPTTISRSTPTSETTYPTSPTSTVTDSTTKIAYSTSMTGTLSTETSLPP------T 370

Query: 825  EQTLPATSTNLAQMSPTFTTTILKTSQPLMTTPGTLSSTA-SLVTGPIAVQTTAGKQLSL 883
              +LP T T    M+   TTT   +S    +TP   SST  S VT  I+  TTA      
Sbjct: 371  SSSLPTTETATTPMTNLVTTTTEISSH---STPSFSSSTIYSTVTSHISTSTTAITSHFT 427

Query: 884  THPEILVPQISTEGGISTERNRVIVDATTGLIPLTSVPT---SAKEMTTKLGVTAEYSPA 940
            T    + P   T   +ST+            IP TS+ T   S+   +T L  T ++   
Sbjct: 428  TSETAVTPTPVTPSSLSTD------------IPTTSLRTLTPSSVGTSTSLTTTTDFPSI 475

Query: 941  SRSLGTSPSPQTTVVSTAEDLAPKSATFAVQSSTQSPTTVSSSASVNSCAVNPCLHNGEC 1000
               + T P+ +T ++S++  +     +  V +++ + +TV  +  +             C
Sbjct: 476  PTDISTLPT-RTHIISSSPSIQSTETSSLVGTTSPTMSTVRMTLRITENTPISSFSTSTC 534

Query: 1001 VADNTSRGYHCRCPPSWQGDDCSVDVN-------ECLSNPCPST 1037
                T     C C P + GD C +          + L   CPST
Sbjct: 535  DNGGTWEQGQCACLPGFSGDRCQLQTRCQNGGQWDGLKCQCPST 578


>gi|239758058 PREDICTED: similar to mucin, partial [Homo sapiens]
          Length = 967

 Score = 93.6 bits (231), Expect = 1e-18
 Identities = 199/794 (25%), Positives = 308/794 (38%), Gaps = 125/794 (15%)

Query: 254 TTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASSPLLDLSSSSESTEKLN 313
           TTS  +P F  ++   E+T+ S    +S    +    + T         SSS  +TE  +
Sbjct: 13  TTSQNTPGFTSSIATTEITSHSPPSFTSSSTTTETPSHSTPG------FSSSIATTETTS 66

Query: 314 NSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVSKTEGFPKDSRIATTSSSVL 373
           +ST   +SS++ T+TM      +   P    S+  +      T  F   S I TT ++  
Sbjct: 67  HSTASFTSSIATTETM------SQNIPGFTSSIATTEITSHSTPSF--TSSITTTETTSQ 118

Query: 374 LSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQNDSPTFGEHQLASSSEVQNG 433
            SPS         +TG+         S+      TS   ++ + +    +  S S +   
Sbjct: 119 SSPSFTSL---ITITGSTSHSTASFTSSITTTETTSHSTRSITSSITTTKRTSHSSLSYT 175

Query: 434 SPMSQTETVSRSVAPMRG----GEITAHWLLTNSTTSADVTGSSASYPEGVNASVLTQFS 489
           S ++ +ET S +V          E T+H     S TSA  T  + S+   +  S +T   
Sbjct: 176 SSIATSETPSHTVPSFTSLITTTESTSH--SNPSLTSAITTTETRSHSPPIFTSSITTI- 232

Query: 490 DSTVQSGGSHTALGDRSYSES-------SSTSSSESLNSSAPRGERSIAGI---SYGQVR 539
           ++T  S  S T+L   + + S        S S++E+ + S P    SIA     S+    
Sbjct: 233 ETTSHSTPSFTSLMTTTETTSLSPPAFTFSISTTETNSHSPPSFTSSIATTETPSHSPPS 292

Query: 540 GTAIEQRTSSDHTDHTYLSSTFTKGERALLSITDNSSSSDIVESSTSYIKISNSSHSEYS 599
            T++   T+++ T H+ LS T          IT   S+S    S TS I  + ++     
Sbjct: 293 FTSL--ITTTESTSHSPLSFTSV--------ITTTESTSHSTPSFTSSIATTETTSHTPP 342

Query: 600 SFFHAQTERSNISSYDGEYAQ--PSTESPVLHTSNLPSYTPTINMPNTSVVLDTDAEFVS 657
           SF    T     S  +  +     +TES      +  S   T  + + S  + T     +
Sbjct: 343 SFTSLITTTETPSHSNPSFTSLITATESTSHSPPSFTSAIATTGITSHSTPIFTSLIATT 402

Query: 658 DSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSILPSTRASVHLLKSTSDASTPWSSSPS 717
           DS+S S+ S +SS +       ++S S   FSS++ +T+ + H   S +   T   S+P 
Sbjct: 403 DSTSHSTPSFTSSITS----TETISHSTPSFSSLITATKTTSHSTPSLTSLITTTKSTPH 458

Query: 718 PLPVSLTTSTSAPLSVSQT---------TLPQSSSTPVLPRARETPVTSFQTSTMTSFMT 768
                   + S+  S SQ           +PQ S            +T F TS +T+  T
Sbjct: 459 --------NASSFTSYSQLHFFDHHHRGHIPQYSQLDFFDHYNRDHLTQF-TSLITTTKT 509

Query: 769 MLHS--SQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESST-- 824
             HS  S TA + S  T       T   +PS     T S     T S  PPS T SST  
Sbjct: 510 TSHSPPSFTALITSTKT-------TSHSTPSF----TSSIATTETTSHSPPSFTSSSTTT 558

Query: 825 ---EQTLP------ATSTNLAQMSPTFTTTILKTSQPLMTTP----------GTLSSTAS 865
                + P      ATS   +   P FT  I  T   L +TP           T  ST S
Sbjct: 559 ETHSHSTPGFSSSIATSKTTSTSPPRFTFAIATTKTTLHSTPRFTLAIASTKTTSHSTPS 618

Query: 866 LVTGPIAVQTTAGKQLSLTHPEILVPQISTEGGISTERNRVIVDATTGLIPLTS----VP 921
           L +    ++TT+    SLT        I+T G IS         + T LI +T       
Sbjct: 619 LTSLITTIETTSHCTPSLT------SSITTSGTISHS-----TPSFTSLITITESTSHST 667

Query: 922 TSAKEMTTKLGVTAEYSPASRSL-------GTSPSPQTTVVSTAEDLAPKSATFAVQSST 974
           TS     T    T+  +P+  SL         S    T+ ++T E  +  + +F   S T
Sbjct: 668 TSFPSSITTTETTSHSTPSFTSLIATTEIISHSTPSYTSSIATTETPSHSTPSFPF-SIT 726

Query: 975 QSPTTVSSSASVNS 988
            + T   S+ S+NS
Sbjct: 727 TTETIPHSTPSLNS 740



 Score = 77.8 bits (190), Expect = 7e-14
 Identities = 156/651 (23%), Positives = 253/651 (38%), Gaps = 94/651 (14%)

Query: 363 SRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQNDSPTFGEH 422
           S IATT ++   +P    S   + +T +     F   ST  E    S      S +    
Sbjct: 6   SSIATTETTSQNTPGFTSSIATTEITSH-SPPSFTSSSTTTE--TPSHSTPGFSSSIATT 62

Query: 423 QLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADVTGSSASYPEGVNA 482
           +  S S     S ++ TET+S+++              T+S  + ++T  S        +
Sbjct: 63  ETTSHSTASFTSSIATTETMSQNIPGF-----------TSSIATTEITSHSTP---SFTS 108

Query: 483 SVLTQFSDSTVQSGGSHTAL----GDRSYSESSSTSSSESLNSSAPRGERSIAGISYGQV 538
           S+ T  +++T QS  S T+L    G  S+S +S TSS  +  +++    RSI        
Sbjct: 109 SITT--TETTSQSSPSFTSLITITGSTSHSTASFTSSITTTETTS-HSTRSITS------ 159

Query: 539 RGTAIEQRTSSDHTDHTYLSSTFTKGERALLSITDNSSSSDIVESSTSYIKISNSSHSEY 598
                   T++  T H+ LS T         SI  + + S  V S TS I  + S+    
Sbjct: 160 ------SITTTKRTSHSSLSYTS--------SIATSETPSHTVPSFTSLITTTESTSHSN 205

Query: 599 SSFFHAQTERSNISSYDGEYAQPSTESPVLHTSNLPSYTPTINMPNTSVVLDTDAEFVSD 658
            S   A T             +  + SP + TS++ +   T +   +   L T  E  S 
Sbjct: 206 PSLTSAITT-----------TETRSHSPPIFTSSITTIETTSHSTPSFTSLMTTTETTSL 254

Query: 659 SSSS---SSSSSSSSSSGPPLPLPSV------SQSHHLFSSILPSTRASVHL-LKSTSDA 708
           S  +   S S++ ++S  PP    S+      S S   F+S++ +T ++ H  L  TS  
Sbjct: 255 SPPAFTFSISTTETNSHSPPSFTSSIATTETPSHSPPSFTSLITTTESTSHSPLSFTSVI 314

Query: 709 STPWSSS---PSPLPVSLTTSTSAPLSVSQTTLPQSSSTPVLPRARETPVTSFQTSTMTS 765
           +T  S+S   PS      TT T++    S T+L  ++ TP       T + +   ST  S
Sbjct: 315 TTTESTSHSTPSFTSSIATTETTSHTPPSFTSLITTTETPSHSNPSFTSLITATESTSHS 374

Query: 766 FMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESSTE 825
             +   +  T  + S STP    +I            T+ST   T      PS T S T 
Sbjct: 375 PPSFTSAIATTGITSHSTPIFTSLIA----------TTDSTSHST------PSFTSSIT- 417

Query: 826 QTLPATSTNLAQMSPTFTTTILKTSQPLMTTPGTLS-STASLVTGPIAVQTTAGKQLSL- 883
                ++  ++  +P+F++ I  T     +TP   S  T +  T   A   T+  QL   
Sbjct: 418 -----STETISHSTPSFSSLITATKTTSHSTPSLTSLITTTKSTPHNASSFTSYSQLHFF 472

Query: 884 -THPEILVPQISTEGGISTERNRVIVDATTGLIPLTSVPTSAKEMTTKLGVTAEYSPASR 942
             H    +PQ S +       NR  +   T LI  T   + +    T L  + + +  S 
Sbjct: 473 DHHHRGHIPQYS-QLDFFDHYNRDHLTQFTSLITTTKTTSHSPPSFTALITSTKTTSHST 531

Query: 943 SLGTSPSPQTTVVSTAEDLAPKSATFAVQSSTQSPTTVSSSASVNSCAVNP 993
              TS    T   S +      S+T     S  +P   SS A+  + + +P
Sbjct: 532 PSFTSSIATTETTSHSPPSFTSSSTTTETHSHSTPGFSSSIATSKTTSTSP 582



 Score = 73.9 bits (180), Expect = 1e-12
 Identities = 186/815 (22%), Positives = 305/815 (37%), Gaps = 94/815 (11%)

Query: 146 TSGKSHAASDAPENLTLLAETADARGRSGSSSRTNFT---ILPVGYSLEIATALTSQSGN 202
           T   SH+      ++T    T+ +     SS  T+ T    +P   SL   T  TS S  
Sbjct: 147 TETTSHSTRSITSSITTTKRTSHSSLSYTSSIATSETPSHTVPSFTSLITTTESTSHSNP 206

Query: 203 LASESLHLPSSSSE----FDERIAAFQTKSGTA----SEMGTERAMGLSEE---WTVHSQ 251
             + ++    + S     F   I   +T S +     S M T     LS     +++ + 
Sbjct: 207 SLTSAITTTETRSHSPPIFTSSITTIETTSHSTPSFTSLMTTTETTSLSPPAFTFSISTT 266

Query: 252 EATTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASSPLLDLSSSSESTEK 311
           E T S   PSF  ++   E  TPS     S P  + L     + S   L  +S   +TE 
Sbjct: 267 E-TNSHSPPSFTSSIATTE--TPSH----SPPSFTSLITTTESTSHSPLSFTSVITTTES 319

Query: 312 LNNSTGLQSSSVSQTKT---------------------------MHVATVFTDGGPRTLR 344
            ++ST   +SS++ T+T                           +  AT  T   P +  
Sbjct: 320 TSHSTPSFTSSIATTETTSHTPPSFTSLITTTETPSHSNPSFTSLITATESTSHSPPSFT 379

Query: 345 SLTVSLGPVSKTEGFPKDSRIATTSSSVLLSPSAVESRRNSRVTGN--PGDEEFI---EP 399
           S   + G  S +      S IATT S+   +PS   S  ++    +  P     I   + 
Sbjct: 380 SAIATTGITSHSTPI-FTSLIATTDSTSHSTPSFTSSITSTETISHSTPSFSSLITATKT 438

Query: 400 STENEFGLTSLRWQNDSPTFGEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWL 459
           ++ +   LTSL     S         S S++       +      S           H  
Sbjct: 439 TSHSTPSLTSLITTTKSTPHNASSFTSYSQLHFFDHHHRGHIPQYSQLDFFDHYNRDH-- 496

Query: 460 LTNSTTSADVTGSSASYPEGVNASVLTQ--FSDSTVQSGGSHTALGDRSYSESSSTSSSE 517
           LT  T+    T +++  P    A + +    S ST     S       S+S  S TSSS 
Sbjct: 497 LTQFTSLITTTKTTSHSPPSFTALITSTKTTSHSTPSFTSSIATTETTSHSPPSFTSSST 556

Query: 518 SLNSSAPRGERSIAGISYGQVRGTAIEQRTSSDHTDHTYLSSTFTKGERALLSITDNSSS 577
           +  + +       + I+  +   T+  + T +  T  T L ST     R  L+I    ++
Sbjct: 557 TTETHSHSTPGFSSSIATSKTTSTSPPRFTFAIATTKTTLHST----PRFTLAIASTKTT 612

Query: 578 SDIVESSTSYIKISNSSHSEYSSFFHAQTERSNISSYDGEYAQ--PSTESPVLHTSNLPS 635
           S    S TS I    ++     S   + T    IS     +      TES    T++ PS
Sbjct: 613 SHSTPSLTSLITTIETTSHCTPSLTSSITTSGTISHSTPSFTSLITITESTSHSTTSFPS 672

Query: 636 YTPTINMPN------TSVVLDTDAEFVSDSSSSSSSSSSS----SSSGPPLPLP-----S 680
              T    +      TS++  T  E +S S+ S +SS ++    S S P  P       +
Sbjct: 673 SITTTETTSHSTPSFTSLIATT--EIISHSTPSYTSSIATTETPSHSTPSFPFSITTTET 730

Query: 681 VSQSHHLFSSILPSTRASVHLLKS-TSDASTPWSSSPSP------LPVSLTTSTSAP-LS 732
           +  S    +S + +T    H +    S  +T  ++SP P      +  + TTS S P  +
Sbjct: 731 IPHSTPSLNSAITTTETMSHSIPGFASSITTSETTSPFPPRFTSLITTTKTTSHSPPSFT 790

Query: 733 VSQTTLPQSSSTPVLPRA--RETPVTSFQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVI 790
            S T+   +S +P+   +    T +TS  T ++TS +T   +S    L   S+    K  
Sbjct: 791 ASLTSTEATSHSPLSFTSVIASTKITSQSTPSLTSLITTTGTSSHNTLGLSSSVDTTKTT 850

Query: 791 TESKSPSLVSLPTESTKAVTTNSPLPPSLTESSTEQTLPATSTNLAQMSPTFTTTILKTS 850
           + S +     + T  T +  T        T   T  + P+ ++++  M  T  ++   TS
Sbjct: 851 SHSTASFTSLIATTETTSHNTPGFTSSIATTEITSHSTPSFTSSITTMETTSRSSPSFTS 910

Query: 851 QPLMTTPGTLS-STASLVTGPIAVQTTAGKQLSLT 884
             L+T  G+ S STAS  +     +TT+    S+T
Sbjct: 911 --LITITGSTSHSTASFTSSITTTETTSHSTPSIT 943



 Score = 55.1 bits (131), Expect = 5e-07
 Identities = 152/665 (22%), Positives = 251/665 (37%), Gaps = 85/665 (12%)

Query: 150 SHAASDAPENLTLLAETADARGRSGSSSRTNFTIL------PVGYSLEIATA-LTSQSGN 202
           +   S  P + T L  T +    S  S  +  T        P  ++  IAT  +TS S  
Sbjct: 334 TETTSHTPPSFTSLITTTETPSHSNPSFTSLITATESTSHSPPSFTSAIATTGITSHSTP 393

Query: 203 LASESLHLPSSSSEFDERIAAFQTKSGTASEMGTERAMGLSEEWTVHSQEATTSAWSPSF 262
           + +  +    S+S          T S T+S   TE    +S      S   T +  +   
Sbjct: 394 IFTSLIATTDSTSH--------STPSFTSSITSTET---ISHSTPSFSSLITATKTTSHS 442

Query: 263 LPALEMGELTTPSRKRNSSG-PDLSWLHFYRTAASSPLLDLSSSSESTEKLNNSTGLQSS 321
            P+L     TT S   N+S     S LHF+       +   S          +     +S
Sbjct: 443 TPSLTSLITTTKSTPHNASSFTSYSQLHFFDHHHRGHIPQYSQLDFFDHYNRDHLTQFTS 502

Query: 322 SVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVS-KTEGFPKDSRIATTSSSVLLSPSAVE 380
            ++ TKT       T   P +  +L  S    S  T  F   S IATT ++    PS   
Sbjct: 503 LITTTKT-------TSHSPPSFTALITSTKTTSHSTPSFT--SSIATTETTSHSPPSFTS 553

Query: 381 SRRNSRVTGN--PGDEEFIEPSTENEFGLTSLRWQNDSPTFGEHQLASSSEVQNGSP--- 435
           S   +    +  PG    I  S          +  + SP      +A++    + +P   
Sbjct: 554 SSTTTETHSHSTPGFSSSIATS----------KTTSTSPPRFTFAIATTKTTLHSTPRFT 603

Query: 436 --MSQTETVSRSVAPMRGG----EITAHW---LLTNSTTSADVTGSSASYPEGVNASVLT 486
             ++ T+T S S   +       E T+H    L ++ TTS  ++ S+ S+   +  +  T
Sbjct: 604 LAIASTKTTSHSTPSLTSLITTIETTSHCTPSLTSSITTSGTISHSTPSFTSLITITEST 663

Query: 487 QFSDSTVQSGGSHTALGDRSYSESSSTS---SSESLNSSAPRGERSIAGISYGQVRGTAI 543
             S ST     S T     S+S  S TS   ++E ++ S P    SIA          + 
Sbjct: 664 --SHSTTSFPSSITTTETTSHSTPSFTSLIATTEIISHSTPSYTSSIATTETPSHSTPSF 721

Query: 544 E-QRTSSDHTDHTY--LSSTFTKGERA-------LLSITDNSSSSDIVESSTSYIKISNS 593
               T+++   H+   L+S  T  E           SIT + ++S      TS I  + +
Sbjct: 722 PFSITTTETIPHSTPSLNSAITTTETMSHSIPGFASSITTSETTSPFPPRFTSLITTTKT 781

Query: 594 -SHSEYSSFFHAQTERSNISSYDGEYAQPSTESPVLHTSNLPSYTPTINMPNTSVVLDTD 652
            SHS  S  F A    +  +S+          S  + + + PS T  I    TS     +
Sbjct: 782 TSHSPPS--FTASLTSTEATSHSPLSFTSVIASTKITSQSTPSLTSLITTTGTS---SHN 836

Query: 653 AEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHL--FSSILPSTRASVHLLKS------ 704
              +S S  ++ ++S S++S   L   + + SH+   F+S + +T  + H   S      
Sbjct: 837 TLGLSSSVDTTKTTSHSTASFTSLIATTETTSHNTPGFTSSIATTEITSHSTPSFTSSIT 896

Query: 705 ---TSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQSSSTPVLPRARETPVTSFQTS 761
              T+  S+P  +S   +  S + ST++  S   TT   S STP +  +  T   +F ++
Sbjct: 897 TMETTSRSSPSFTSLITITGSTSHSTASFTSSITTTETTSHSTPSITSSVTTAERTFHST 956

Query: 762 TMTSF 766
              +F
Sbjct: 957 PSYAF 961


>gi|239752529 PREDICTED: similar to mucin [Homo sapiens]
          Length = 594

 Score = 93.2 bits (230), Expect = 2e-18
 Identities = 159/625 (25%), Positives = 261/625 (41%), Gaps = 80/625 (12%)

Query: 287 WLHFYRTAASSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTM-HVATVFTDGGPRTLRS 345
           W+H      S  +   +S   +T+  ++S    +S+++ T+T  H   +FT         
Sbjct: 5   WVHIPHETPSHTVPSFTSLITTTDSTSHSNPSLTSAITTTETRSHSPPIFTS-------- 56

Query: 346 LTVSLGPVSKTE-GFPKDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENE 404
              S+  +  T    P  + + TT+ +  LSP A     ++  T +     F       E
Sbjct: 57  ---SITTIETTSHSTPSFTSLMTTTETTSLSPPAFTFSISTTETNSHSPPSFTSSIATTE 113

Query: 405 FGLTSLRWQNDSPTFGEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNST 464
                    +  P+F    L +++E  + SP+S T  ++ +       E T+H   T S 
Sbjct: 114 TP------SHSPPSFTS--LITTTESTSHSPLSFTSVITTT-------ESTSH--STPSF 156

Query: 465 TSADVTGSSASYPEGVNASVLTQFSDSTVQSGGSHTALGDRSYSESSSTSSSESLNSSAP 524
           TS+  T  + S+      S++T  +++   S  S T+L   + +ES+S S     ++ A 
Sbjct: 157 TSSIATTETTSHTPPSFTSLITT-TETPSHSNPSFTSL--ITATESTSHSPPSFTSAIAT 213

Query: 525 RGERSIAGISYGQVRGTAIEQRTSSDHTDHTYLSS-----TFTKGERALLS-ITDNSSSS 578
            G  S +   +  +  T      S+ H+  ++ SS     T +    +  S IT   ++S
Sbjct: 214 TGITSHSTPIFTSLIATT----DSTSHSTPSFTSSITSTETISHSTPSFSSLITATKTTS 269

Query: 579 DIVESSTSYIKISNSSHSEYS-SFFHAQTERSNISSYDGEYAQPSTESPVLHTSNLPSYT 637
               S TS I  +N+SHS  S +     TE ++ S+        + E+    T +L S  
Sbjct: 270 HSTPSLTSLITTTNTSHSTPSLTSLVTSTETASHSTPSFTSLITTIEATSHSTPSLTSSI 329

Query: 638 PTINMPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLF----SSILP 693
            T    + S    T    +++S+S S+ S +S+ +       + + SH +     S I P
Sbjct: 330 TTTGTTSHSTPSFTYLTTITESTSHSTPSLTSAIT------TTETMSHSILGFTPSIISP 383

Query: 694 STRASVHLLKSTSDASTPWSSSPSPLPVSLTTSTSAP------LSVSQTTLPQSSSTPVL 747
           ST + + L+ +T    TP  S+PS  P S+TT+ SA        S   TT   S S PV 
Sbjct: 384 STPSYISLIATT---ETPSHSTPS-FPSSITTTQSASHSTPSLTSAISTTEAMSHSIPVF 439

Query: 748 PR-ARETPVTSFQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLP--TE 804
                 T  TS      TS +T      T    S S P    +IT +K+ S  S P  T 
Sbjct: 440 TSLITTTETTSHLPPRFTSLIT------TTKTTSHSPPSFTALITSTKTTS-HSTPSFTS 492

Query: 805 STKAVTTNSPLPPSLTESST-----EQTLPATSTNLAQMSPTFTTTILKTSQPLMTTPGT 859
           S     T S  PPS T SST       + P  S+++A  S T +T+  + +  + TT  T
Sbjct: 493 SIATTETTSHSPPSFTSSSTTTETHSHSTPGFSSSIA-TSKTTSTSPPRFTFAIATTKTT 551

Query: 860 LSSTASLVTGPIAVQTTAGKQLSLT 884
           L ST        + +TT+    SLT
Sbjct: 552 LHSTPRFTLAIASTKTTSHSTPSLT 576



 Score = 67.4 bits (163), Expect = 9e-11
 Identities = 109/455 (23%), Positives = 189/455 (41%), Gaps = 68/455 (14%)

Query: 547 TSSDHTDHTYLSSTFTKGERALLSITDNSSSSDIVESSTSYIKISNSSHSEYSSFFHAQT 606
           T++D T H+  S T      A+ +    S S  I  SS + I+ ++ S   ++S     T
Sbjct: 25  TTTDSTSHSNPSLT-----SAITTTETRSHSPPIFTSSITTIETTSHSTPSFTSLM-TTT 78

Query: 607 ERSNISSYDGEYAQPSTESPVLHTSNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSS 666
           E +++S     ++  +TE+   ++ + PS+T        S +  T+    S  S +S  +
Sbjct: 79  ETTSLSPPAFTFSISTTET---NSHSPPSFT--------SSIATTETPSHSPPSFTSLIT 127

Query: 667 SSSSSSGPPLPLPSVSQSHHLFSSILPSTRASVHLLKSTSDASTPWSSSPSPLPVSLTTS 726
           ++ S+S  PL           F+S++ +T ++ H             S+PS      TT 
Sbjct: 128 TTESTSHSPLS----------FTSVITTTESTSH-------------STPSFTSSIATTE 164

Query: 727 TSAPLSVSQTTLPQSSSTPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADLKSQSTPHQ 786
           T++    S T+L  ++ TP       T + +   ST  S  +   +  T  + S STP  
Sbjct: 165 TTSHTPPSFTSLITTTETPSHSNPSFTSLITATESTSHSPPSFTSAIATTGITSHSTPIF 224

Query: 787 EKVI--TESKSPSLVSLPTESTKAVTTNSPLPPSLTESSTEQTLPATSTNLAQMSPTFTT 844
             +I  T+S S S  S  +  T   T +   P   + SS       TS +   ++   TT
Sbjct: 225 TSLIATTDSTSHSTPSFTSSITSTETISHSTP---SFSSLITATKTTSHSTPSLTSLITT 281

Query: 845 TILKTSQPLMTTPGTLSSTASLVTGPIAVQTTAGKQLSLTHPEILVPQISTEGGISTERN 904
           T    S P +T+  T + TAS  T       T  +  S + P  L   I+T G  S    
Sbjct: 282 TNTSHSTPSLTSLVTSTETASHSTPSFTSLITTIEATSHSTPS-LTSSITTTGTTS---- 336

Query: 905 RVIVDATTGLIPLTSVPTSAKEMTTKL--GVTAEYSPASRSLGTSP---SPQT----TVV 955
                +T     LT++  S    T  L   +T   + +   LG +P   SP T    +++
Sbjct: 337 ----HSTPSFTYLTTITESTSHSTPSLTSAITTTETMSHSILGFTPSIISPSTPSYISLI 392

Query: 956 STAEDLAPKSATF-----AVQSSTQSPTTVSSSAS 985
           +T E  +  + +F       QS++ S  +++S+ S
Sbjct: 393 ATTETPSHSTPSFPSSITTTQSASHSTPSLTSAIS 427



 Score = 64.3 bits (155), Expect = 8e-10
 Identities = 154/617 (24%), Positives = 246/617 (39%), Gaps = 122/617 (19%)

Query: 250 SQEATTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASSPLLDLSSSSEST 309
           S   T S   PSF  ++   E  TPS     S P  + L     + S   L  +S   +T
Sbjct: 93  STTETNSHSPPSFTSSIATTE--TPSH----SPPSFTSLITTTESTSHSPLSFTSVITTT 146

Query: 310 EKLNNSTGLQSSSVSQTK-TMHVATVFTDGGPRTLRSLTVSLGPVSKTEGFPKDSRIATT 368
           E  ++ST   +SS++ T+ T H    FT         +T +  P      F   S I  T
Sbjct: 147 ESTSHSTPSFTSSIATTETTSHTPPSFTS-------LITTTETPSHSNPSF--TSLITAT 197

Query: 369 SSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQNDSPTFGEHQLASSS 428
            S+    PS   +   + +T +         ST      TSL    DS +       SS 
Sbjct: 198 ESTSHSPPSFTSAIATTGITSH---------STPI---FTSLIATTDSTSHSTPSFTSS- 244

Query: 429 EVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADVTGSSASYPEGVNASVLTQF 488
                  ++ TET+S S  P     ITA    ++ST S                S++T  
Sbjct: 245 -------ITSTETISHS-TPSFSSLITATKTTSHSTPSL--------------TSLIT-- 280

Query: 489 SDSTVQSGGSHTALGDRSYSESSSTSSSESLNSSAPRGERSIAGISYGQVRGTAIEQRTS 548
           + +T  S  S T+L   + + S ST S  SL ++      S   ++            T+
Sbjct: 281 TTNTSHSTPSLTSLVTSTETASHSTPSFTSLITTIEATSHSTPSLT---------SSITT 331

Query: 549 SDHTDHTYLSSTFTKGERALLSITDNSSSSDIVESSTSYIKISNSSHSEYSSFFHAQTER 608
           +  T H+  S T+      L +IT+++               S+S+ S  S+    +T  
Sbjct: 332 TGTTSHSTPSFTY------LTTITEST---------------SHSTPSLTSAITTTETMS 370

Query: 609 SNISSYDGEYAQPSTES--PVLHTSNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSS 666
            +I  +      PST S   ++ T+  PS++ T + P++     T  +  S S+ S +S+
Sbjct: 371 HSILGFTPSIISPSTPSYISLIATTETPSHS-TPSFPSSI----TTTQSASHSTPSLTSA 425

Query: 667 SSSSSSGPPLPLPSVSQSHHLFSSILPSTRASVHL-LKSTSDASTPWSSSPSPLPVSLTT 725
            S++         ++S S  +F+S++ +T  + HL  + TS  +T  ++S SP       
Sbjct: 426 ISTTE--------AMSHSIPVFTSLITTTETTSHLPPRFTSLITTTKTTSHSP------P 471

Query: 726 STSAPLSVSQTTLPQSSSTPVLPRA-RETPVTSFQTSTMTSFMTMLHSSQTADLKSQSTP 784
           S +A ++ ++TT   S STP    +   T  TS    + TS      SS T +  S STP
Sbjct: 472 SFTALITSTKTT---SHSTPSFTSSIATTETTSHSPPSFTS------SSTTTETHSHSTP 522

Query: 785 HQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESSTEQTLPATSTNLAQMS-PTFT 843
                I  SK+ S  + P   T A+ T      +   S+   TL   ST     S P+ T
Sbjct: 523 GFSSSIATSKTTS--TSPPRFTFAIATTK----TTLHSTPRFTLAIASTKTTSHSTPSLT 576

Query: 844 TTILKTSQPLMTTPGTL 860
           + I      L   P +L
Sbjct: 577 SLITTIETTLHLRPASL 593



 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 115/516 (22%), Positives = 197/516 (38%), Gaps = 83/516 (16%)

Query: 629  HTSNLPSYTPTINMPN-TSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHL 687
            H  ++P  TP+  +P+ TS++  TD+   S+ S +S+ +++ + S  P           +
Sbjct: 4    HWVHIPHETPSHTVPSFTSLITTTDSTSHSNPSLTSAITTTETRSHSP----------PI 53

Query: 688  FSSILPSTRASVHLLKS-TSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQSSSTPV 746
            F+S + +   + H   S TS  +T  ++S SP   + + ST+   S S  +   S +T  
Sbjct: 54   FTSSITTIETTSHSTPSFTSLMTTTETTSLSPPAFTFSISTTETNSHSPPSFTSSIATT- 112

Query: 747  LPRARETPVTSFQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTEST 806
                 ETP  S    + TS +T   S+  + L   S        TES S S  S  T S 
Sbjct: 113  -----ETP--SHSPPSFTSLITTTESTSHSPLSFTSVI----TTTESTSHSTPSF-TSSI 160

Query: 807  KAVTTNSPLPPSLTESSTEQTLPATSTNLAQMSPTFTTTILKTSQPLMTTPGTLSSTASL 866
                T S  PPS T   T    P+ S      +P+FT+ I  T     + P   S+ A+ 
Sbjct: 161  ATTETTSHTPPSFTSLITTTETPSHS------NPSFTSLITATESTSHSPPSFTSAIAT- 213

Query: 867  VTGPIAVQTTAGKQLSLTHPEILVPQISTEGGI-STERNRVIVDATTGLIPLTSVPTSAK 925
             TG  +  T     L  T         S    I STE       + + LI  T   + + 
Sbjct: 214  -TGITSHSTPIFTSLIATTDSTSHSTPSFTSSITSTETISHSTPSFSSLITATKTTSHST 272

Query: 926  EMTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSATFAVQSSTQSPTTVSSSAS 985
               T L  T   S ++ SL       T++V++ E  +  + +F    +T   T+ S+ + 
Sbjct: 273  PSLTSLITTTNTSHSTPSL-------TSLVTSTETASHSTPSFTSLITTIEATSHSTPSL 325

Query: 986  VNSCAVNPCLHNGECVADNTSRGYHCRCPPSWQGDDCSVDVNECLSNPCPSTAMCNNTQG 1045
             +S                T+ G      PS+        + E  S+  PS      T  
Sbjct: 326  TSSI---------------TTTGTTSHSTPSFT---YLTTITESTSHSTPSLTSAITTTE 367

Query: 1046 SFICKCPVGYQLEKGICNLVRTFVTEFKLKRTFLNTTVEKHSDLQEVENEITKTLNMCFS 1105
            +          +   I     + ++        L  T              T+T +    
Sbjct: 368  T----------MSHSILGFTPSIISPSTPSYISLIAT--------------TETPSHSTP 403

Query: 1106 ALPSYIRSTVHASRESNAVVISLQTTFSLASNVTLF 1141
            + PS I +T  AS  + ++  ++ TT +++ ++ +F
Sbjct: 404  SFPSSITTTQSASHSTPSLTSAISTTEAMSHSIPVF 439


>gi|83367077 mucin 16 [Homo sapiens]
          Length = 14507

 Score = 91.7 bits (226), Expect = 4e-18
 Identities = 223/985 (22%), Positives = 366/985 (37%), Gaps = 175/985 (17%)

Query: 146  TSGKSHAASDAPENLTLLAETA--DARGRSGSSSRTNFTILPVGYSLEIATALTSQSGNL 203
            TS   + +S + E LT   +T   +A   S S++ TN      G+         SQS  L
Sbjct: 6854 TSSPPNLSSTSHEILTTDEDTTAIEAMHPSTSTAATNVETTSSGHG--------SQSSVL 6905

Query: 204  ASESLHLPSSSSEFDERIAAFQTKSGTASEMGTERAMGLSEEWTVHSQEATTSAWSPSFL 263
            A          SE  +  A   T S T        +M +S E T   +E+T S       
Sbjct: 6906 AD---------SEKTKATAPMDTTS-TMGHTTVSTSMSVSSETTKIKRESTYS-----LT 6950

Query: 264  PALEMGELTTPSRKRNSSGPDLSWLHFYRTAASSPLLDLSSSSESTEKLNNSTGLQSSSV 323
            P L    ++  +     +   LS +    TA  S     SS   S    + ST L   S 
Sbjct: 6951 PGLRETSISQNASFSTDTSIVLSEVPTGTTAEVSRTEVTSSGRTSIPGPSQSTVLPEIST 7010

Query: 324  SQTKTMHVATVFTDGGPRTLRSLTVSLGPVSKTEGFPKDSRIATTSSSVLLSPSAVESRR 383
                 +  +   T+    T+ + T   GP   T         +TT S      +  +   
Sbjct: 7011 RTMTRLFASPTMTESAEMTIPTQT---GPSGSTSQDTLTLDTSTTKSQAKTHSTLTQRFP 7067

Query: 384  NSRVTG----NPGDEEF-IEPSTENEFGLTSLRWQNDSPTFGEHQLASSSEVQ-NGSPMS 437
            +S +T      PGD  +   PS EN   L SL   +   T     ++S+  V  + SP+ 
Sbjct: 7068 HSEMTTLMSRGPGDMSWQSSPSLENPSSLPSLL--SLPATTSPPPISSTLPVTISSSPLP 7125

Query: 438  QTETVSRSVAPMRGGEITAHWLLTNSTTSAD-------VTGSSASYPEGVNASVLTQFSD 490
             T  ++ S         T+  L+T+S             TG   +  E V+ S  T  S+
Sbjct: 7126 VTSLLTSSPVTTTDMLHTSPELVTSSPPKLSHTSDERLTTGKDTTNTEAVHPSTNTAASN 7185

Query: 491  STVQSGGSHTALGDRSYSESSSTSSSESLNSSAPRGERSIAGISYGQVRGTAIEQRTSSD 550
              + S G  +     + SE+S  +S   + S+    E +   IS      T+  Q+ S  
Sbjct: 7186 VEIPSSGHESPSSALADSETSKATSPMFITSTQ---EDTTVAISTPHFLETSRIQKES-- 7240

Query: 551  HTDHTYLSSTFTKGERALLSITDNSSSSDIVESSTSYIKISNSSHSEYSSFFHAQTERSN 610
                  +SS   K    L     +  +S  +E+S    ++S  + +E S      + R++
Sbjct: 7241 ------ISSLSPK----LRETGSSVETSSAIETSAVLSEVSIGATTEISRTEVTSSSRTS 7290

Query: 611  ISSYDGEYAQPSTESPVLHTSNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSSSSSS 670
            IS      +  ST  P + T+        I  P + ++ ++    +   +S   S+S S+
Sbjct: 7291 ISG-----SAESTMLPEISTTR-----KIIKFPTSPILAESSEMTIKTQTSPPGSTSEST 7340

Query: 671  SSGPPLPLPSVSQSHHLFSSILPSTRASVHLLKSTSDASTPWS-----SSP--------- 716
             +      PS+  +H   +  LP +  +  + +   D   P S     +SP         
Sbjct: 7341 FTLDTSTTPSLVITHSTMTQRLPHSEITTLVSRGAGDVPRPSSLPVEETSPPSSQLSLSA 7400

Query: 717  --SPLPVSLT---TSTSAPLSVSQTTLPQSSSTPVLPRARETPVTSFQTSTMTSFMTMLH 771
              SP PVS T   +S S+  SV+    P    T  +  A   P TS   S  ++ + +L 
Sbjct: 7401 MISPSPVSSTLPASSHSSSASVTSLLTPGQVKTTEVLDASAEPETSSPPSLSSTSVEILA 7460

Query: 772  SSQTADLKSQSTPHQEKVITE-------SKSPSLVSLPTESTKAV-----------TTNS 813
            +S+      +  P     +T+        +SPS V   +E+TKA            T+ S
Sbjct: 7461 TSEVTTDTEKIHPFSNTAVTKVGTSSSGHESPSSVLPDSETTKATSAMGTISIMGDTSVS 7520

Query: 814  PLPPSLTESSTEQTLPATS--TNLAQMSPTFTTTILKTSQPLMTTPGTLSSTASLVTGPI 871
             L P+L+ +   Q+ PA+S  T L + S +  T++   +  +++   T ++T    T  I
Sbjct: 7521 TLTPALSNTRKIQSEPASSLTTRLRETSTSEETSLATEANTVLSKVSTGATTEVSRTEAI 7580

Query: 872  AVQTTA--GKQLSLTHPEI---LVPQISTEGGISTERNRVIVDATTG--------LIPLT 918
            +   T+  G + S    +I    +P+IS    + TE  ++ +   TG         + L 
Sbjct: 7581 SFSRTSMSGPEQSTMSQDISIGTIPRISASS-VLTESAKMTITTQTGPSESTLESTLNLN 7639

Query: 919  SVPTSA--------------KEMTTKLG------------VTAEYSPASRSLG----TSP 948
            +  T +               EMTT +G               E SP S  L     TSP
Sbjct: 7640 TATTPSWVETHSIVIQGFPHPEMTTSMGRGPGGVSWPSPPFVKETSPPSSPLSLPAVTSP 7699

Query: 949  SPQTTV-----------VSTAEDLAPKSATFAVQSSTQSPTTVSSSASVNSC-------- 989
             P +T            V++     P + T  + +ST+  T+ SSS S  S         
Sbjct: 7700 HPVSTTFLAHIPPSPLPVTSLLTSGPATTTDILGTSTEPGTSSSSSLSTTSHERLTTYKD 7759

Query: 990  -----AVNPCLHNGECVADNTSRGY 1009
                 AV+P  + G      TS GY
Sbjct: 7760 TAHTEAVHPSTNTGGTNVATTSSGY 7784



 Score = 90.9 bits (224), Expect = 8e-18
 Identities = 181/851 (21%), Positives = 347/851 (40%), Gaps = 121/851 (14%)

Query: 196  LTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTASEMGTERAMGLSEEWTVHSQEATT 255
            LT+      +E++H  ++++  +  I +   +S +++   +E +   S  +   +QE TT
Sbjct: 7163 LTTGKDTTNTEAVHPSTNTAASNVEIPSSGHESPSSALADSETSKATSPMFITSTQEDTT 7222

Query: 256  SAWS-PSFLPA--LEMGELTTPSRKRNSSGPDLSWLHFYRTAASSPLLDLSSSSE--STE 310
             A S P FL    ++   +++ S K   +G  +       T+A    + + +++E   TE
Sbjct: 7223 VAISTPHFLETSRIQKESISSLSPKLRETGSSVETSSAIETSAVLSEVSIGATTEISRTE 7282

Query: 311  KLNNSTGLQSSSVSQTKTMHVAT-----------VFTDGGPRTLRSLTVSLGPVSKTEGF 359
              ++S    S S   T    ++T           +  +    T+++ T   G  S++  F
Sbjct: 7283 VTSSSRTSISGSAESTMLPEISTTRKIIKFPTSPILAESSEMTIKTQTSPPGSTSEST-F 7341

Query: 360  PKDSRIATTSSSVLLSPSAVESRRNSRVTG--NPGDEEFIEPSTENEFGLTSLRWQNDSP 417
              D+  +TT S V+   +  +   +S +T   + G  +   PS        SL  +  SP
Sbjct: 7342 TLDT--STTPSLVITHSTMTQRLPHSEITTLVSRGAGDVPRPS--------SLPVEETSP 7391

Query: 418  TFGEHQLA---SSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNST---TSADVTG 471
               +  L+   S S V +  P S   + +   + +  G++    +L  S    TS+  + 
Sbjct: 7392 PSSQLSLSAMISPSPVSSTLPASSHSSSASVTSLLTPGQVKTTEVLDASAEPETSSPPSL 7451

Query: 472  SSASYPEGVNASVLTQ------FSDSTVQSGGSHTALGDRSYS----ESSSTSSSESLNS 521
            SS S      + V T       FS++ V   G+ ++ G  S S    +S +T ++ ++ +
Sbjct: 7452 SSTSVEILATSEVTTDTEKIHPFSNTAVTKVGTSSS-GHESPSSVLPDSETTKATSAMGT 7510

Query: 522  SAPRGERSIAGISYGQVRGTAIEQRTSSDHTDHTYLSSTFTKGERALLSITDNSSSSDIV 581
             +  G+ S++ ++        I+   +S  T  T L  T T  E +L +           
Sbjct: 7511 ISIMGDTSVSTLTPALSNTRKIQSEPASSLT--TRLRETSTSEETSLAT----------- 7557

Query: 582  ESSTSYIKISNSSHSEYSSFFHAQTERSNISSYDGEYAQPSTESPVLHTSNLPSYTPTIN 641
            E++T   K+S  + +E S     +TE  + S       + ST S  +    +P  + +  
Sbjct: 7558 EANTVLSKVSTGATTEVS-----RTEAISFSRTSMSGPEQSTMSQDISIGTIPRISAS-- 7610

Query: 642  MPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSILPSTRASVHL 701
                SV+ ++    ++  +  S S+  S+ +      PS  ++H +     P    +  +
Sbjct: 7611 ----SVLTESAKMTITTQTGPSESTLESTLNLNTATTPSWVETHSIVIQGFPHPEMTTSM 7666

Query: 702  LKSTSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQSSSTPVLPRARET--PVTSFQ 759
             +     S  W   PSP  V  T+  S+PLS+   T P   ST  L     +  PVTS  
Sbjct: 7667 GRGPGGVS--W---PSPPFVKETSPPSSPLSLPAVTSPHPVSTTFLAHIPPSPLPVTSLL 7721

Query: 760  TSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSL 819
            TS   +   +L +S                 TE  + S  SL T S + +TT        
Sbjct: 7722 TSGPATTTDILGTS-----------------TEPGTSSSSSLSTTSHERLTTYK------ 7758

Query: 820  TESSTEQTLPATS---TNLAQMSPTF--TTTILKTSQPLMTTPGTLSSTASLVTGPIAVQ 874
              + TE   P+T+   TN+A  S  +   +++L  S P+ TT  T+  T+ L + P  ++
Sbjct: 7759 DTAHTEAVHPSTNTGGTNVATTSSGYKSQSSVLADSSPMCTT-STMGDTSVLTSTPAFLE 7817

Query: 875  TTAGKQLSLTHPEILVPQISTEGGISTERNRVIVDATTGLIPLTSVPTSAKEMTTKLGVT 934
            T   +++       L P +    G     +      T     L+ VPT A    +K  VT
Sbjct: 7818 T---RRIQTELASSLTPGLRESSG-----SEGTSSGTKMSTVLSKVPTGATTEISKEDVT 7869

Query: 935  AEYSPASRSLGTSPSPQTT-------VVSTAEDLAPKSATFAVQSSTQSPTTVSSSASVN 987
            +   PA  ++    S +T        V++ + ++   + T  + ++TQ  +T+ +S++ +
Sbjct: 7870 SIPGPAQSTISPDISTRTVSWFSTSPVMTESAEITMNTHTSPLGATTQGTSTLDTSSTTS 7929

Query: 988  SCAVNPCLHNG 998
                +  +  G
Sbjct: 7930 LTMTHSTISQG 7940



 Score = 89.0 bits (219), Expect = 3e-17
 Identities = 237/980 (24%), Positives = 381/980 (38%), Gaps = 166/980 (16%)

Query: 130  QEDFSTVSSKEGVMVQTSGKSHAASDAPENLTLLAETADARGRSGSSSRTNFTILPVGYS 189
            +E  S++S K    ++ +G S   S A E   +L+E +   G +   SRT  T       
Sbjct: 7238 KESISSLSPK----LRETGSSVETSSAIETSAVLSEVSI--GATTEISRTEVT------- 7284

Query: 190  LEIATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKS--GTASEMGTERAM---GLSE 244
               +++ TS SG+  +ES  LP  S+    +I  F T      +SEM  +      G + 
Sbjct: 7285 ---SSSRTSISGS--AESTMLPEISTT--RKIIKFPTSPILAESSEMTIKTQTSPPGSTS 7337

Query: 245  EWTVHSQEATTSAW---SPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASSPLLD 301
            E T     +TT +      +    L   E+TT   +     P  S L    T+  S  L 
Sbjct: 7338 ESTFTLDTSTTPSLVITHSTMTQRLPHSEITTLVSRGAGDVPRPSSLPVEETSPPSSQLS 7397

Query: 302  LS---SSSESTEKLNNSTGLQSSSVS------QTKTMHVATVFTD---GGPRTLRSLTVS 349
            LS   S S  +  L  S+   S+SV+      Q KT  V     +     P +L S +V 
Sbjct: 7398 LSAMISPSPVSSTLPASSHSSSASVTSLLTPGQVKTTEVLDASAEPETSSPPSLSSTSVE 7457

Query: 350  LGPVSK----TEGFPKDSRIATT----SSSVLLSPSAV----ESRRNSRVTGN---PGDE 394
            +   S+    TE     S  A T    SSS   SPS+V    E+ + +   G     GD 
Sbjct: 7458 ILATSEVTTDTEKIHPFSNTAVTKVGTSSSGHESPSSVLPDSETTKATSAMGTISIMGDT 7517

Query: 395  EF--IEPSTENEFGLTSLRWQN------DSPTFGEHQLASS-----SEVQNGSP--MSQT 439
                + P+  N   + S    +      ++ T  E  LA+      S+V  G+   +S+T
Sbjct: 7518 SVSTLTPALSNTRKIQSEPASSLTTRLRETSTSEETSLATEANTVLSKVSTGATTEVSRT 7577

Query: 440  ETVSRSVAPMRGGEITAHWLLTNSTTSADVTGSSASYPEGVNASVLTQFSDSTV--QSGG 497
            E +S S   M G E         ST S D+  S  + P    +SVLT+ +  T+  Q+G 
Sbjct: 7578 EAISFSRTSMSGPE--------QSTMSQDI--SIGTIPRISASSVLTESAKMTITTQTGP 7627

Query: 498  SHTALGDRSYSESSSTSS-------------SESLNSSAPRGERSIAGISYGQVRGTA-- 542
            S + L       +++T S                + +S  RG   ++  S   V+ T+  
Sbjct: 7628 SESTLESTLNLNTATTPSWVETHSIVIQGFPHPEMTTSMGRGPGGVSWPSPPFVKETSPP 7687

Query: 543  -----IEQRTSSDHTDHTYLS----------STFTKGERALLSI----TDNSSSSDIVES 583
                 +   TS      T+L+          S  T G      I    T+  +SS    S
Sbjct: 7688 SSPLSLPAVTSPHPVSTTFLAHIPPSPLPVTSLLTSGPATTTDILGTSTEPGTSSSSSLS 7747

Query: 584  STSYIKISNSSHSEYSSFFHAQTER--SNISSYDGEYAQPSTESPVLHTSNLPSYTPTIN 641
            +TS+ +++    + ++   H  T    +N+++    Y    ++S VL  S+    T T  
Sbjct: 7748 TTSHERLTTYKDTAHTEAVHPSTNTGGTNVATTSSGY---KSQSSVLADSSPMCTTST-- 7802

Query: 642  MPNTSVVLDTDAEF----VSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSILPSTRA 697
            M +TSV+  T A      +    +SS +     SSG          S  L  S +P+   
Sbjct: 7803 MGDTSVLTSTPAFLETRRIQTELASSLTPGLRESSGSEGTSSGTKMSTVL--SKVPTGAT 7860

Query: 698  SVHLLKSTSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQSSSTPVLPRARETPVTS 757
            +    +  +    P  S+ SP   + T S  +   V   +   + +T   P    T  TS
Sbjct: 7861 TEISKEDVTSIPGPAQSTISPDISTRTVSWFSTSPVMTESAEITMNTHTSPLGATTQGTS 7920

Query: 758  FQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTE------------- 804
               ++ T+ +TM HS+      SQ   H +      + P  VS  +              
Sbjct: 7921 TLDTSSTTSLTMTHSTI-----SQGFSHSQMSTLMRRGPEDVSWMSPPLLEKTRPSFSLM 7975

Query: 805  STKAVTTNSPLPPSLTESSTEQTLPATSTNLAQMSPTFTTTILKTSQPLMTTPGTLSSTA 864
            S+ A T+ SP+  +L ES +   LP TS   + ++ T T  + K+S+P+  +P  LSST+
Sbjct: 7976 SSPATTSPSPVSSTLPESISSSPLPVTSLLTSGLAKT-TDMLHKSSEPVTNSPANLSSTS 8034

Query: 865  SLVTGPIAVQTTAGKQLSLTHPEI--LVPQISTEGGISTERNRVIVDATTGLIPLTSVPT 922
              +     V T   K    THP     V  + T        + V+ D+ T  +    V T
Sbjct: 8035 VEILATSEVTTDTEK----THPSSNRTVTDVGTSSSGHESTSFVLADSQTSKVTSPMVIT 8090

Query: 923  SAKEMTTKLGVTAEYSPASR---------SLG---TSPSPQTTVVSTAEDLAPKSATFAV 970
            S  E T+    T  +   SR         +LG   TS S  T++ +    +     T A 
Sbjct: 8091 STMEDTSVSTSTPGFFETSRIQTEPTSSLTLGLRKTSSSEGTSLATEMSTVLSGVPTGAT 8150

Query: 971  QSSTQSPTTVSSSASVNSCA 990
               +++  T SS  S++  A
Sbjct: 8151 AEVSRTEVTSSSRTSISGFA 8170



 Score = 87.4 bits (215), Expect = 8e-17
 Identities = 214/936 (22%), Positives = 354/936 (37%), Gaps = 144/936 (15%)

Query: 114  ESNTEAHVENITFYQNQEDFSTVSSKEGVMVQTSGKSHAASDAPENLTL-LAETADARGR 172
            +S T      +      ED S  +S  G        S   ++   +LTL L +T+ + G 
Sbjct: 8077 DSQTSKVTSPMVITSTMEDTSVSTSTPGFFET----SRIQTEPTSSLTLGLRKTSSSEGT 8132

Query: 173  S-GSSSRTNFTILPVGYSLEIA-TALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGT 230
            S  +   T  + +P G + E++ T +TS S           +S S F +   + +T + T
Sbjct: 8133 SLATEMSTVLSGVPTGATAEVSRTEVTSSSR----------TSISGFAQLTVSPETSTET 8182

Query: 231  ASEMGTERAMGLSEEWTVHSQEATTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHF 290
             + + T   M  S E  + +Q     + +P     +++   TTP+           W+  
Sbjct: 8183 ITRLPTSSIMTESAEMMIKTQTDPPGS-TPESTHTVDIS--TTPN-----------WVET 8228

Query: 291  YRTAASSPLLDLSSSSESTEKLNNSTG--LQSSSVSQTKTMHVATVFTDGGPRTLRSLTV 348
            + T          S SE T  ++ S G  L  S  S  +T   +++ +          T 
Sbjct: 8229 HSTVTQR-----FSHSEMTTLVSRSPGDMLWPSQSSVEETSSASSLLS-------LPATT 8276

Query: 349  SLGPVSKT--EGFPKDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFG 406
            S  PVS T  E FP  S   T+    LL+P  V +     ++  PG       S+ +   
Sbjct: 8277 SPSPVSSTLVEDFPSASLPVTS----LLNPGLVITTDRMGISREPGTSSTSNLSSTSHER 8332

Query: 407  LTSLRWQNDSPTFGEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTS 466
            LT+L                   V        T T   +V     G  +   +L++S T 
Sbjct: 8333 LTTLE----------------DTVDTEDMQPSTHTAVTNVRTSISGHESQSSVLSDSETP 8376

Query: 467  ADVTGSSASYPEG---VNASVLTQFSDSTVQSGGSHTALGDRSYSESSSTSSSESLNSSA 523
               +    +Y  G   V+ S    F  S +Q   + +       S    TSSSE + SSA
Sbjct: 8377 KATSPMGTTYTMGETSVSISTSDFFETSRIQIEPTSSLT-----SGLRETSSSERI-SSA 8430

Query: 524  PRGERSIAGISYGQVRGTAIEQRTSSDHTDHTYLSSTFTKGERALLSITDNSSSSDIVES 583
              G   ++ +  G     +  +  SS  T  +         + +  +IT  S+S  + ES
Sbjct: 8431 TEGSTVLSEVPSGATTEVSRTEVISSRGTSMSGPDQFTISPDISTEAITRLSTSPIMTES 8490

Query: 584  STSYIKISNSSHSEYSSFFHAQTERSNISSYDGEYAQPSTESPVLHTSNLPSYTPTINMP 643
            + S I I   S    S       + S  + + G ++  S        + L S TP  ++P
Sbjct: 8491 AESAITIETGSPGATSEGT-LTLDTSTTTFWSGTHSTASPGFSHSEMTTLMSRTPG-DVP 8548

Query: 644  NTSVVLDTDAEFVSDSSSSSSSSSSS---------SSSGPP----LPLPSVSQSHHLFSS 690
              S+    +A  VS S SS + +S+S         SSS  P    L L  V  +  L +S
Sbjct: 8549 WPSLPSVEEASSVSSSLSSPAMTSTSFFSTLPESISSSPHPVTALLTLGPVKTTDMLRTS 8608

Query: 691  ILPSTRASVHL------LKSTSDAST------PWSSSP---------------SPLPVSL 723
              P T +  +L      + +TS+ +       P S++P               S L   +
Sbjct: 8609 SEPETSSPPNLSSTSAEILATSEVTKDREKIHPSSNTPVVNVGTVIYKHLSPSSVLADLV 8668

Query: 724  TTSTSAPLSVSQT--TLPQSSSTPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADLKSQ 781
            TT  ++P++ + T      S+STP  P    T  TS  TS +    T   +S   +  + 
Sbjct: 8669 TTKPTSPMATTSTLGNTSVSTSTPAFPETMMTQPTSSLTSGLREISTSQETSSATERSAS 8728

Query: 782  STPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESSTEQTLPATSTNLAQMSPT 841
             +       T+      +SL   ST     ++  P   TE+ T  + P T+T  A+M   
Sbjct: 8729 LSGMPTGATTKVSRTEALSLGRTSTPGPAQSTISPEISTETITRISTPLTTTGSAEM--- 8785

Query: 842  FTTTILKTSQPLMTTPGTL---SSTASLVTGPIAVQTTAGKQLSLTHPEILVPQ-ISTEG 897
              T   KT     ++ GT    +S+ +   G  +  T       +T P    P+ +S   
Sbjct: 8786 --TITPKTGHSGASSQGTFTLDTSSRASWPGTHSAATHRSPHSGMTTPMSRGPEDVSWPS 8843

Query: 898  GISTER-----NRVIVDATTGLIPLTSVPTSAKEMTTKLGVTAEYSP----ASRSLGTSP 948
              S E+     + V + A T   PL S P+ +   ++ L VT+ ++P     +  L TS 
Sbjct: 8844 RPSVEKTSPPSSLVSLSAVTSPSPLYSTPSESSH-SSPLRVTSLFTPVMMKTTDMLDTSL 8902

Query: 949  SPQTTV-----VSTAEDLAPKSATFAVQSSTQSPTT 979
             P TT      +++ E LA   AT   ++   S  T
Sbjct: 8903 EPVTTSPPSMNITSDESLATSKATMETEAIQLSENT 8938



 Score = 86.7 bits (213), Expect = 1e-16
 Identities = 201/921 (21%), Positives = 350/921 (38%), Gaps = 129/921 (14%)

Query: 135   TVSSKEGVMVQTSGKSHAASDAPENLTLLAETADARGRSGSSSR--TNFTILPVGYSL-- 190
             T+SS E     +   SH    +   LT+  E         +SSR  T+ TI  +  S   
Sbjct: 11117 TLSSSEPETTPSMATSHGVEASSAVLTVSPEVPGMVTSLVTSSRAVTSTTIPTLTISSDE 11176

Query: 191   -EIATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTASEMGTERAMGLSEEWTVH 249
              E  T+L + S      ++   + S      + +  T SG+ +   +   +  S+  T+ 
Sbjct: 11177 PETTTSLVTHSEAKMISAIPTLAVSPTVQGLVTSLVTSSGSETSAFSNLTVASSQPETID 11236

Query: 250   SQEATTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFY-RTAASSPLLDLSSSSES 308
             S  A     + S +P L +           S+G   + +      A SS  L  ++S  S
Sbjct: 11237 SWVAHPGTEASSVVPTLTV-----------STGEPFTNISLVTHPAESSSTLPRTTSRFS 11285

Query: 309   TEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLG-PVSKTEGFPKDSRIAT 367
               +L+      +S  +++ +  ++T  + G P  L SL  S G  +S T     +S   +
Sbjct: 11286 HSELDTMPSTVTSPEAESSSA-ISTTISPGIPGVLTSLVTSSGRDISATFPTVPESPHES 11344

Query: 368   TSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQNDSPTFGEHQLASS 427
              +++  ++  AV S    R T N    E   P T              +P+      +  
Sbjct: 11345 EATASWVTHPAVTSTTVPRTTPNYSHSE---PDT--------------TPSIAT---SPG 11384

Query: 428   SEVQNGSPMSQTETVSRSVAPMRGGEITAHWL--------LTNSTTSADVTGSSASYPEG 479
             +E  +  P   T TVS  V  M   ++T+           LT S+   + T S  +Y E 
Sbjct: 11385 AEATSDFP---TITVSPDVPDMVTSQVTSSGTDTSITIPTLTLSSGEPETTTSFITYSET 11441

Query: 480   VNASVLTQFSDSTVQSGGSHTALGDRSYSESSSTSSSESLNSSAPRGERSIAGISYGQVR 539
               +S +       V  G S         S + ST++  +L  +    E +   + +    
Sbjct: 11442 HTSSAIPTLP---VSPGASKMLTSLVISSGTDSTTTFPTLTETPYEPETTAIQLIHPAET 11498

Query: 540   GTAIEQRT------SSDHTDHTYLSSTFTKGERALLSITDNSSSSDIVES---------S 584
              T + + T       SD T    ++S   +   A+ + T +   SD+V S         S
Sbjct: 11499 NTMVPRTTPKFSHSKSDTTLPVAITSPGPEASSAVSTTTISPDMSDLVTSLVPSSGTDTS 11558

Query: 585   TSYIKISNSSHSEYSS---FFHAQTERSNIS------SYDGEYAQPS--------TESPV 627
             T++  +S + +   ++     H     + +S      S+ G    PS        T S V
Sbjct: 11559 TTFPTLSETPYEPETTATWLTHPAETSTTVSGTIPNFSHRGSDTAPSMVTSPGVDTRSGV 11618

Query: 628   LHTSNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPP-------LPLPS 680
               T+  PS    +    TS   DT     + + S     +++SS+  P       +P+ +
Sbjct: 11619 PTTTIPPSIPGVVTSQVTSSATDTSTAIPTLTPSPGEPETTASSATHPGTQTGFTVPIRT 11678

Query: 681   V--SQSHHLFSSILPSTRASVHLLKSTSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTL 738
             V  S+   + S +    + S  + ++TS  S    SSP   PV  T+  +   S   TT+
Sbjct: 11679 VPSSEPDTMASWVTHPPQTSTPVSRTTSSFS---HSSPDATPVMATSPRTEASSAVLTTI 11735

Query: 739   PQSSSTPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSL 798
                  +P  P    + +TS   +T T+  T+ HS    +  +  + H  +  T    P+ 
Sbjct: 11736 -----SPGAPEMVTSQITSSGAATSTTVPTLTHSPGMPETTALLSTHP-RTETSKTFPAS 11789

Query: 799   VSLP--TESTKAVT------TNSPLPPSLTESSTEQTLPATSTNLAQMSPTFTTTILKTS 850
                P  +E+T ++T      T++ LP   T S    TL  T T+   +SPT +  +   +
Sbjct: 11790 TVFPQVSETTASLTIRPGAETSTALPTQTTSSLF--TLLVTGTSRVDLSPTASPGVSAKT 11847

Query: 851   QPLMTTPGTLSSTASLVTGPIAVQTTAGKQLSLTHPEILVPQISTEGGISTERNRVIVDA 910
              PL T PGT +ST         +  T+   L L     L   ++T     T  + + +  
Sbjct: 11848 APLSTHPGTETST---------MIPTSTLSLGLLETTGL---LATSSSAETSTSTLTLTV 11895

Query: 911   TTGLIPLTSVPTSAKEMTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSATFAV 970
             +  +  L+S   +  +  T      E SP+  S+G  P    TV  T   L P       
Sbjct: 11896 SPAVSGLSSASITTDKPQTVTSWNTETSPSVTSVG-PPEFSRTVTGTTMTLIPSEMPTPP 11954

Query: 971   QSS---TQSPTTVSSSASVNS 988
             ++S     SPTT+  +  V +
Sbjct: 11955 KTSHGEGVSPTTILRTTMVEA 11975



 Score = 86.3 bits (212), Expect = 2e-16
 Identities = 220/969 (22%), Positives = 369/969 (38%), Gaps = 144/969 (14%)

Query: 76   ATPGPSYRAPEPGAATQRGPSGRAPRGGSADAAWKHWPESNTEAHVENITFYQNQEDFST 135
            +T G  + +PEPG+A     S  AP   SA         S  +  +   + +  Q   S 
Sbjct: 259  STTGYPFSSPEPGSAGHSRISTSAPLSSSA---------SVLDNKISETSIFSGQ---SL 306

Query: 136  VSSKEGVMVQTSGKSHAASDAPENLTLL-AETADARGRSGSSS---------RTNFTILP 185
             S     + +    +   S  P ++TL  AET+  R RS  SS         +T  TIL 
Sbjct: 307  TSPLSPGVPEARASTMPNSAIPFSMTLSNAETSAERVRSTISSLGTPSISTKQTAETILT 366

Query: 186  VGY--------SLEIATALTSQ----SGNLASESLHLPSSSSEFDERIAAFQTKSGTASE 233
                       S  IA  L S+     G L   S    +++S     ++       + S 
Sbjct: 367  FHAFAETMDIPSTHIAKTLASEWLGSPGTLGGTSTSALTTTSPSTTLVSEETNTHHSTSG 426

Query: 234  MGTERAMGLSEEWTVHSQEATTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRT 293
              TE  +  S      S     S  + + +P L    L +  R  +             T
Sbjct: 427  KETEGTLNTSMTPLETSAPGEESEMTATLVPTLGFTTLDSKIRSPSQVSSSHPTRELRTT 486

Query: 294  AASSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPV 353
             ++S     S+++  +  +  +T   +S  S   +   A  F++       +  V   P 
Sbjct: 487  GSTSGRQSSSTAAHGSSDILRATTSSTSKASSWTSESTAQQFSE----PQHTQWVETSPS 542

Query: 354  SKTEGFPKDSRIA----TTSSSVLLSPSAVESRRNSRV--------------TGNPGDEE 395
             KTE  P  + +A    T+  SV+   + +++     +              T  P   +
Sbjct: 543  MKTERPPASTSVAAPITTSVPSVVSGFTTLKTSSTKGIWLEETSADTLIGESTAGPTTHQ 602

Query: 396  FIEPSTENEFGLTSLRWQNDSPTFGEHQLASSSE------VQNGSPMSQTETVSRSVA-P 448
            F  P+  +  G +S R    +        ASS          NG P+S +  VS++ A  
Sbjct: 603  FAVPTGISMTGGSSTRGSQGTTHLLTRATASSETSADLTLATNGVPVSVSPAVSKTAAGS 662

Query: 449  MRGGEITAHWLLTNSTTSADVTGSSASYPEGVNASVLT-----QFSDSTVQSGGSHTALG 503
               G     + + +S      +  S+++ EG +  +        FS     S G HT + 
Sbjct: 663  SPPGGTKPSYTMVSSVIPETSSLQSSAFREGTSLGLTPLNTRHPFSSPEPDSAG-HTKI- 720

Query: 504  DRSYSESSSTSSSESLNSSAPRGERSIAGISYGQVRGTAIEQRTSSDHTDHTYLSSTFTK 563
                      S+S  L SSA   E  ++  S      T    + +S  T  T   ST TK
Sbjct: 721  ----------STSIPLLSSASVLEDKVSATS------TFSHHKATSSITTGTPEISTKTK 764

Query: 564  GERALLS---ITDNSSSSDIVESSTSYIKISNSSHSEYSSFF-----HAQTERSNISSYD 615
               A+LS   +++ ++S + V ++TS +   + S  E +         A+T  S      
Sbjct: 765  PSSAVLSSMTLSNAATSPERVRNATSPLTHPSPSGEETAGSVLTLSTSAETTDSPNIHPT 824

Query: 616  GEYAQPSTESPVLHTSNLPSYT---PTINMPNTSVVLDTDAEFVSDSSSSSSSSSSSSSS 672
            G     S+ESP   T +LPS +    T +    S  L T  E   ++S+ S S   +S S
Sbjct: 825  GTLTSESSESP--STLSLPSVSGVKTTFSSSTPSTHLFTSGEETEETSNPSVSQPETSVS 882

Query: 673  GPPLPLPSVSQSHHLFSSI--LPSTRA---SVHL---LKSTSDASTPWSSSPSPLPVSLT 724
                 L S S    +F ++   P+  A   S HL   L++TS  S   S+  +   +S  
Sbjct: 883  RVRTTLASTSVPTPVFPTMDTWPTRSAQFSSSHLVSELRATSSTSVTNSTGSALPKISHL 942

Query: 725  TSTSAPLSVSQTTL-----PQSSSTPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADLK 779
            T T+     ++ T      PQS++ P      +T + S  T+  TS  ++  +   +   
Sbjct: 943  TGTATMSQTNRDTFNDSAAPQSTTWPETSPRFKTGLPSATTTVSTSATSLSATVMVSKFT 1002

Query: 780  SQSTPHQEKVITESKSPSLVSLPTESTK------AVTTNSPLPPS-LTESSTEQT-LPAT 831
            S +T   E   T  + PS   L TE+T         +TN P+    +TE   + + LP  
Sbjct: 1003 SPATSSME--ATSIREPSTTILTTETTNGPGSMAVASTNIPIGKGYITEGRLDTSHLPIG 1060

Query: 832  STNLAQMSPTFTTTILKTSQPLMTTPG-TLSSTASLVTGPIA--VQTTAGKQLSLTHPEI 888
            +T  ++ S  F  T+ K S  +  +P  ++ +  S   G  +  V T +     LT  EI
Sbjct: 1061 TTASSETSMDF--TMAKESVSMSVSPSQSMDAAGSSTPGRTSQFVDTFSDDVYHLTSREI 1118

Query: 889  LVPQISTEGGISTERNRVIVDATTGLIPLTSVPTSAKEMTTKLGVTAEYSPASRSLGTSP 948
             +P+  T   ++ +         T   P +  P SA+  +T LG+ +       S  +SP
Sbjct: 1119 TIPRDGTSSALTPQ--------MTATHPPSPDPGSAR--STWLGILS-------SSPSSP 1161

Query: 949  SPQTTVVST 957
            +P+ T+ ST
Sbjct: 1162 TPKVTMSST 1170



 Score = 84.7 bits (208), Expect = 5e-16
 Identities = 172/753 (22%), Positives = 301/753 (39%), Gaps = 96/753 (12%)

Query: 291  YRTAASSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSL 350
            + T ++ P     +S   T      T +  S    +KT    T  T      LR  ++S 
Sbjct: 4845 HSTVSAYPEPSKVTSPNVTTSTMEDTTISRSIPKSSKTTRTETETTSSLTPKLRETSISQ 4904

Query: 351  GPVSKTEGFPKDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSL 410
               S TE      +   T ++  +S + V S  ++   G       ++ STE    L++ 
Sbjct: 4905 EITSSTETSTVPYK-ELTGATTEVSRTDVTSSSSTSFPGPDQSTVSLDISTETNTRLSTS 4963

Query: 411  RWQNDSPTFGEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADVT 470
                +S         ++    +G+    T T+  S    + G    H  +T+  +  DVT
Sbjct: 4964 PIMTESAEI----TITTQTGPHGATSQDTFTMDPSNTTPQAG---IHSAMTHGFSQLDVT 5016

Query: 471  GSSASYPEGVN----ASVLTQFSDSTVQSGGSHTALGDRSYSESSSTSSSESLNSSAPRG 526
               +  P+ V+     SV    S S+  S  + T     + S  SST   + L+S  P  
Sbjct: 5017 TLMSRIPQDVSWTSPPSVDKTSSPSSFLSSPAMT-----TPSLISSTLPEDKLSS--PMT 5069

Query: 527  ERSIAG-ISYGQVRGTAIEQRTSSDHTDHTYLSSTFTKGERALLSITDNSSSSDI---VE 582
                +G +    +  T +E  TSS       L +  +  ++ L +  D+  + +I   + 
Sbjct: 5070 SLLTSGLVKITDILRTRLEPVTSS-------LPNFSSTSDKILATSKDSKDTKEIFPSIN 5122

Query: 583  SSTSYIKISNSSHSEYS-SFFHAQTERSN----ISSYDGEYAQPSTESPV---LHTSNL- 633
            +  + +K +NS H  +S +   ++T ++     I++  G+ A PST  PV     T+N+ 
Sbjct: 5123 TEETNVKANNSGHESHSPALADSETPKATTQMVITTTVGDPA-PSTSMPVHGSSETTNIK 5181

Query: 634  --PSYTPTINMPNTSVVLD----TDAEFV-----SDSSSSSSSSSSSSSSGPPLPLPSVS 682
              P+Y  T  +  TS   +    TD  F+     + + +  SS+  +SSS        +S
Sbjct: 5182 REPTYFLTPRLRETSTSQESSFPTDTSFLLSKVPTGTITEVSSTGVNSSS-------KIS 5234

Query: 683  QSHHLFSSILPSTRASVHLLKSTSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQSS 742
               H  S++ P T         TS   T  +       +++TT  S P S S +TLP  +
Sbjct: 5235 TPDHDKSTVPPDTFTGEIPRVFTSSIKTKSAE------MTITTQASPPESASHSTLPLDT 5288

Query: 743  STPVLPRARETPVT-SFQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSL 801
            ST +      + VT  F  S +T+ M M       ++   +TP  E+    S   SL+S 
Sbjct: 5289 STTLSQGGTHSTVTQGFPYSEVTTLMGM----GPGNVSWMTTPPVEET---SSVSSLMSS 5341

Query: 802  PTESTKAVTTNSPLPPSLTESSTEQTLPATSTNLAQMSPTFTTTILKTSQPLMTTPGTLS 861
            P     A+T+ SP+  +  +S     LP T+   + +    TT +L T+ P   T    +
Sbjct: 5342 P-----AMTSPSPVSSTSPQSIPSSPLPVTALPTSVL--VTTTDVLGTTSPESVTSSPPN 5394

Query: 862  STASLVTGPIAVQTTAGKQLSLTH-PEILVPQISTEGGISTERNRVIVD----------A 910
             ++     P   + TA  + ++ H     V  + T G     ++ V+ D          +
Sbjct: 5395 LSSITHERPATYKDTAHTEAAMHHSTNTAVTNVGTSGSGHKSQSSVLADSETSKATPLMS 5454

Query: 911  TTGLIPLTSVPTSAKEMTTKLGV----TAEYSPASRSLGTS-PSPQTTVVSTAEDLAPKS 965
            TT  +  TSV TS   ++    +    TA  SP  R   TS  +  TT  +TA    P  
Sbjct: 5455 TTSTLGDTSVSTSTPNISQTNQIQTEPTASLSPRLRESSTSEKTSSTTETNTAFSYVPTG 5514

Query: 966  ATFAVQSSTQSPTTVSSSASVNSCAVNPCLHNG 998
            A     S T+  ++ +S + ++   + P +  G
Sbjct: 5515 A-ITQASRTEISSSRTSISDLDRPTIAPDISTG 5546



 Score = 84.7 bits (208), Expect = 5e-16
 Identities = 191/942 (20%), Positives = 346/942 (36%), Gaps = 126/942 (13%)

Query: 134  STVSSKEGVMVQTSGKSHAASDAPENLTLLAETADARGRSGSSSRTNFTILPVGYSLEIA 193
            ST S+     V TS  + + ++  +     + +   R  S S   ++ T     +S    
Sbjct: 5454 STTSTLGDTSVSTSTPNISQTNQIQTEPTASLSPRLRESSTSEKTSSTTETNTAFSYVPT 5513

Query: 194  TALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTASEMGTERAMGLSEEWTVHSQEA 253
             A+T  S    S S    +S S+ D    A    +G  + + T   M  S E TV +Q  
Sbjct: 5514 GAITQASRTEISSSR---TSISDLDRPTIAPDISTGMITRLFTSPIMTKSAEMTVTTQTT 5570

Query: 254  TTSAWSPSFLP------ALEMGELTTPSRK---------RNSSGPDLSWLH---FYRTAA 295
            T  A S   LP        + G  +T S+          R+ +  D+SW+       T++
Sbjct: 5571 TPGATSQGILPWDTSTTLFQGGTHSTVSQGFPHSEITTLRSRTPGDVSWMTTPPVEETSS 5630

Query: 296  SSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVSK 355
               L+  S +S S     +   + SS +  T  +    V T     T     V+  P + 
Sbjct: 5631 GFSLMSPSMTSPSPVSSTSPESIPSSPLPVTALLTSVLVTTTNVLGTTSPEPVTSSPPNL 5690

Query: 356  TEGFPKDSRIATTSSSVLLSPSAVESRRNSRV----TGNPGDEEFIEPSTENE------- 404
            +   P   R+ T   +            N+ V    T   G E       ++        
Sbjct: 5691 SS--PTQERLTTYKDTAHTEAMHASMHTNTAVANVGTSISGHESQSSVPADSHTSKATSP 5748

Query: 405  ----FGLTSLRWQNDSPTFGEH--QLASSSEVQNG----------SPMSQTETVSRSVAP 448
                F +        +P F E   Q  S+S +  G          + +++T TV   V  
Sbjct: 5749 MGITFAMGDTSVSTSTPAFFETRIQTESTSSLIPGLRDTRTSEEINTVTETSTVLSEVPT 5808

Query: 449  MRGGEITAHWLLTNSTTSADVTGSSASYPEGVNASVLTQFSDSTVQSGGSHTALGDRSYS 508
                E++   ++T+S T+      S   P  ++   +T+ S     +G +  A+ +++  
Sbjct: 5809 TTTTEVSRTEVITSSRTTISGPDHSKMSPY-ISTETITRLSTFPFVTGSTEMAITNQTGP 5867

Query: 509  ESSSTSSSESLNSSAPRGERSIAGISYGQVRGTAIEQRTSSDHTDHTYLSSTFTKGERAL 568
              + + ++ +L++S           S     GT         H++ T   S  TKG    
Sbjct: 5868 IGTISQATLTLDTS-----------STASWEGTHSPVTQRFPHSEETTTMSRSTKG---- 5912

Query: 569  LSITDNSSSSDIVESSTSYIKISNSSHSEYSSFFHAQTERSNISSYDGEYAQPSTESPVL 628
                   S   + E+S+    +   + + +SS + A +  S           P++  PV 
Sbjct: 5913 ---VSWQSPPSVEETSSPSSPVPLPAITSHSSLYSAVSGSS-----------PTSALPV- 5957

Query: 629  HTSNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSSSSSS-SSGPPLPLPSVSQSHHL 687
             TS L S         T  +LDT +E V+ S  S+SS S    +S       ++  S + 
Sbjct: 5958 -TSLLTS-----GRRKTIDMLDTHSELVTSSLPSASSFSGEILTSEASTNTETIHFSENT 6011

Query: 688  FSSILPSTRASVHLLKSTSDASTPWSSSPSPLPVSLT----TSTSAPLSVSQTTLPQSSS 743
              + + +T +   L  S S  S P   +P  +  S+      STS P S     + + S+
Sbjct: 6012 AETNMGTTNSMHKLHSSVSIHSQPSGHTPPKVTGSMMEDAIVSTSTPGSPETKNVDRDST 6071

Query: 744  TPVLPRARETPVTSFQTSTMTS---FMTMLHSSQTADLKSQSTPHQEKVITES-KSPSLV 799
            +P+ P  +E        ST  S   F ++   + T   +++ T +    +  S +S    
Sbjct: 6072 SPLTPELKEDSTALVMNSTTESNTVFSSVSLDAATEVSRAEVTYYDPTFMPASAQSTKSP 6131

Query: 800  SLPTESTKAVTTNSPLPPSLTESSTEQTLPATSTNLAQMSPTFTTTILKTSQP------- 852
             +  E++ + + + PL  S  ++   QT P+  T+L Q++   +T       P       
Sbjct: 6132 DISPEASSSHSNSPPLTISTHKTIATQTGPSGVTSLGQLTLDTSTIATSAGTPSARTQDF 6191

Query: 853  ----------------LMTTPGTLSSTASLVTGPIAVQTTAGKQLSLTHPEILVPQISTE 896
                            L T+P +     SL +    + TT+   ++ T  E     + + 
Sbjct: 6192 VDSETTSVMNNDLNDVLKTSPFSAEEANSLSSQAPLLVTTSPSPVTSTLQEHSTSSLVSV 6251

Query: 897  GGISTERNRVIVDATTGLIPLTSVPTSAKEMTTKLGVTAE-------YSPASRSLGTSPS 949
              + T     I D  T L P+T  P + +        T +        + A  ++GT+ S
Sbjct: 6252 TSVPTPTLAKITDMDTNLEPVTRSPQNLRNTLATSEATTDTHTMHPSINTAVANVGTTSS 6311

Query: 950  PQTTVVSTAEDLAPKSATFAVQSSTQSPTTVSSSASVNSCAV 991
            P     + + D  P  AT AV  ++ S  ++ S++   S A+
Sbjct: 6312 PNEFYFTVSPDSDPYKATSAVVITSTSGDSIVSTSMPRSSAM 6353



 Score = 84.7 bits (208), Expect = 5e-16
 Identities = 195/860 (22%), Positives = 341/860 (39%), Gaps = 105/860 (12%)

Query: 163  LAETADARGRS-GSSSRTNFTILPVGYSLEIAT---------ALTSQSGNLASESLHLPS 212
            L E++ + G S G+   T  + +P G + EI+          A ++ S ++++ ++   S
Sbjct: 7833 LRESSGSEGTSSGTKMSTVLSKVPTGATTEISKEDVTSIPGPAQSTISPDISTRTVSWFS 7892

Query: 213  SSSEFDERIAAFQTKSGTASEMGTERAMGLSEEWTVHSQEATTSAWSPSFLPALEMGELT 272
            +S    E  A     + T+    T +     +  +  S   T S  S  F       +++
Sbjct: 7893 TSPVMTES-AEITMNTHTSPLGATTQGTSTLDTSSTTSLTMTHSTISQGF----SHSQMS 7947

Query: 273  TPSRKRNSSGP-DLSWLHFYRTAASSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHV 331
            T  R+    GP D+SW+       + P   L SS  +T     S+ L  S  S    + V
Sbjct: 7948 TLMRR----GPEDVSWMSPPLLEKTRPSFSLMSSPATTSPSPVSSTLPESISSSP--LPV 8001

Query: 332  ATVFTDGGPRTLRSLTVSLGPVSKTEGFPKDSRIATTSSSVLLSPSAVESRRNSRVTGNP 391
             ++ T G  +T   L  S  PV              T+S   LS ++VE    S VT   
Sbjct: 8002 TSLLTSGLAKTTDMLHKSSEPV--------------TNSPANLSSTSVEILATSEVTT-- 8045

Query: 392  GDEEFIEPSTENEFGLTSLRWQNDSPTFGEHQLASSSEVQNGSPMSQTETVS-RSVAPMR 450
             D E   PS+     +T +   +         LA S   +  SPM  T T+   SV+   
Sbjct: 8046 -DTEKTHPSSNRT--VTDVGTSSSGHESTSFVLADSQTSKVTSPMVITSTMEDTSVSTST 8102

Query: 451  GGEITAHWLLTNSTTSADVTGSSASYPEGVNASVLTQFSDSTVQSGGSHTALGDRSYSES 510
             G      + T  T+S  +     S  EG   S+ T+ S  TV SG    A  + S +E 
Sbjct: 8103 PGFFETSRIQTEPTSSLTLGLRKTSSSEGT--SLATEMS--TVLSGVPTGATAEVSRTEV 8158

Query: 511  SSTSSSE-----SLNSSAPRGERSIAGISYGQVRGTAIEQ--RTSSD------HTDHTYL 557
            +S+S +       L  S      +I  +    +   + E   +T +D       + HT  
Sbjct: 8159 TSSSRTSISGFAQLTVSPETSTETITRLPTSSIMTESAEMMIKTQTDPPGSTPESTHTVD 8218

Query: 558  SSTFTKGERALLSITDNSSSSDIVESSTSYIKISNSSHSEYSSFFHAQTERSNISSYDGE 617
             ST         ++T   S S++    T+ +     S S     + +Q+     SS    
Sbjct: 8219 ISTTPNWVETHSTVTQRFSHSEM----TTLV-----SRSPGDMLWPSQSSVEETSSASSL 8269

Query: 618  YAQPSTESPVLHTSNLPSYTPTINMPNTSV-----VLDTDAEFVSDSSSSSSSSSSSSSS 672
             + P+T SP   +S L    P+ ++P TS+     V+ TD   +S    +SS+S+ SS+S
Sbjct: 8270 LSLPATTSPSPVSSTLVEDFPSASLPVTSLLNPGLVITTDRMGISREPGTSSTSNLSSTS 8329

Query: 673  GPPLPLPSVSQSHHLFSSILPSTRASVHLLKSTSDASTPWSSSPSPLPVSLTTSTSAPLS 732
               L   +  +       + PST  +V  ++++        S  S L  S T   ++P+ 
Sbjct: 8330 HERL---TTLEDTVDTEDMQPSTHTAVTNVRTSISGH---ESQSSVLSDSETPKATSPMG 8383

Query: 733  VSQTTLPQSSSTPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITE 792
             + T    S S         + +    TS++TS +    SS+    +  S      V++E
Sbjct: 8384 TTYTMGETSVSISTSDFFETSRIQIEPTSSLTSGLRETSSSE----RISSATEGSTVLSE 8439

Query: 793  SKSPSLVSLP-TE--STKAVTTNSPLPPSLTESSTEQTLPATSTNLAQMSPTFTTTILKT 849
              S +   +  TE  S++  + + P   +++   + + +   ST+        +   ++T
Sbjct: 8440 VPSGATTEVSRTEVISSRGTSMSGPDQFTISPDISTEAITRLSTSPIMTESAESAITIET 8499

Query: 850  SQPLMTTPGTLSSTASLVTGPIAVQTTAGKQLSLTHPEILVPQISTEGGISTERNRVIVD 909
              P  T+ GTL+   S  T      +TA    S  H E+      T G +       + +
Sbjct: 8500 GSPGATSEGTLTLDTSTTTFWSGTHSTASPGFS--HSEMTTLMSRTPGDVPWPSLPSVEE 8557

Query: 910  ATTGLIPLTSVPTSAKEMTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSATFA 969
            A++      S   S+  MT+    T+ +S    S+ +SP P T +++    L P   T  
Sbjct: 8558 ASS-----VSSSLSSPAMTS----TSFFSTLPESISSSPHPVTALLT----LGPVKTTDM 8604

Query: 970  VQSS----TQSPTTVSSSAS 985
            +++S    T SP  +SS+++
Sbjct: 8605 LRTSSEPETSSPPNLSSTSA 8624



 Score = 82.8 bits (203), Expect = 2e-15
 Identities = 208/890 (23%), Positives = 338/890 (37%), Gaps = 126/890 (14%)

Query: 164   AETADARGRSGSS-----------SRTNFTILPVGYSLEIATALTSQSGNLASESLHLPS 212
             + TA A+ R+ SS           S T  TI  +G +  +       S    SE+  +P+
Sbjct: 9810  SNTAVAKVRTSSSVHESHSSVLADSETTITIPSMGITSAVDDTTVFTSNPAFSETRRIPT 9869

Query: 213   SSSEFDERIAAFQTKSGTASEMGTERAMGLSEEWTVHSQEATTSAWSPSFLPALEMGELT 272
               +        F    G      +E    ++E   V     T++    S    +    + 
Sbjct: 9870  EPT--------FSLTPGFRETSTSEETTSITETSAVLYGVPTSATTEVSMTEIMSSNRIH 9921

Query: 273   TPSRKRNSSGPDLSWLHFYRTAASSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVA 332
              P   +++  PD+      R ++SS + + +  + +T+K +     QS+    T T  +A
Sbjct: 9922  IPDSDQSTMSPDIITEVITRLSSSSMMSESTQMTITTQKSSPGATAQSTLTLATTTAPLA 9981

Query: 333   TVFTDGGPRTLRSLTVSLGPVSKTEGFPKDSRIA--TTSSSVLLS-------------PS 377
                +   PR L S   +L   S      K S     T+SSS LLS             P 
Sbjct: 9982  RTHSTVPPRFLHSEMTTLMSRSPENPSWKSSLFVEKTSSSSSLLSLPVTTSPSVSSTLPQ 10041

Query: 378   AVESRRNSRVTG--NPGDEEFIEPSTENEFGLTSLRWQNDSPTFGEHQLASSSEVQNGSP 435
             ++ S   S VT    PG  +  + STE    L+     N S T  E  + ++SEV     
Sbjct: 10042 SIPSSSFS-VTSLLTPGMVKTTDTSTEPGTSLS----PNLSGTSVE--ILAASEV----- 10089

Query: 436   MSQTETV--SRSVAPMRGGEITAHWLLTNSTTSADVTGSSASYPEGVNASVLTQFSDSTV 493
              + TE +  S S+A    G  ++   L  S+ S     S A+YP G  +S+      +++
Sbjct: 10090 TTDTEKIHPSSSMAVTNVGTTSSGHEL-YSSVSIHSEPSKATYPVGTPSSMAETSISTSM 10148

Query: 494   QSGGSHTALGDRSYSESSS----TSSSESLNSSAPRGERSIAGISYGQVRGTAIEQRTSS 549
              +    T      +S  +S    T+ S   +S  P    S  G        T + Q + +
Sbjct: 10149 PANFETTGFEAEPFSHLTSGFRKTNMSLDTSSVTPTNTPSSPG-------STHLLQSSKT 10201

Query: 550   DHTDHTYLSSTFTKGERALLSITDNSSSSDIVESSTSYIKISNSSHSEYSSFFHAQTERS 609
             D T     SS             D   +S   E     I   N+S S         TE +
Sbjct: 10202 DFTSSAKTSS------------PDWPPASQYTEIPVDIITPFNASPS--------ITEST 10241

Query: 610   NISSY-DGEYAQPSTESP-VLHTSNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSSS 667
              I+S+ +  +    TES   L T  LPS   TI   +T  V+ + +E ++ S +++    
Sbjct: 10242 GITSFPESRFTMSVTESTHHLSTDLLPS-AETI---STGTVMPSLSEAMT-SFATTGVPR 10296

Query: 668   SSSSSGPPLPLPSVSQSHHLFSSILPSTRASVHLLKSTSDASTPWSSSPSPLPVSLTTST 727
             + S SG P             S+I  S  +S  +  S+S  +T   SS  P    +T+S+
Sbjct: 10297 AISGSGSPFSRTESGPGDATLSTIAESLPSSTPVPFSSSTFTTT-DSSTIPALHEITSSS 10355

Query: 728   SAPLSVSQTTLPQSSSTPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADLKSQSTPHQE 787
             + P  V  +   +SS+T      R   V++  TS+         SS   D +   +    
Sbjct: 10356 ATPYRVDTSLGTESSTT----EGRLVMVSTLDTSSQPG---RTSSSPILDTRMTESVELG 10408

Query: 788   KVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESSTEQTLPATSTNLAQMSP------- 840
              V +  + PSL +  T +   +   + +P       T + +    T+ +  SP       
Sbjct: 10409 TVTSAYQVPSLSTRLTRTDGIMEHITKIPNEAAHRGTIRPVKGPQTSTSPASPKGLHTGG 10468

Query: 841   ----TFTTTILKTSQPLMTTPGTLSSTASLVTGPIAVQT--TAGKQLSLTHPE---ILVP 891
                   TTT LKT+   + T    + T S+ T  +   T   A  Q++ T P    I  P
Sbjct: 10469 TKRMETTTTALKTTTTALKTTSRATLTTSVYTPTLGTLTPLNASMQMASTIPTEMMITTP 10528

Query: 892   QISTEGGISTERNRVIVDA-TTGLIPLTSVPTSAKEMTTKLGVT----AEYSPASRSLGT 946
              +  +   +T      + A T+  +P T+     +E  T   +     AE SP  ++L  
Sbjct: 10529 YVFPDVPETTSSLATSLGAETSTALPRTTPSVFNRESETTASLVSRSGAERSPVIQTLDV 10588

Query: 947   SPS-PQTT---VVSTAEDLAPKSAT----FAVQSSTQSPTTVSSSASVNS 988
             S S P TT   V+  AE +   S T    F  +  T S T  S  A V+S
Sbjct: 10589 SSSEPDTTASWVIHPAETIPTVSKTTPNFFHSELDTVSSTATSHGADVSS 10638



 Score = 82.4 bits (202), Expect = 3e-15
 Identities = 185/848 (21%), Positives = 332/848 (39%), Gaps = 125/848 (14%)

Query: 225  QTKSGTASEMGTERAMGLSEEWTVHSQEATTSAWSPSFLPALEMG---ELTTPSRKRNSS 281
            +T+S +A+ M T  A+G +E  T   +  T S   PS  P++E+     LT  +    + 
Sbjct: 1787 RTESSSATLMST--ALGSTEN-TGKEKLRTASMDLPSPTPSMEVTPWISLTLSNAPNTTD 1843

Query: 282  GPDLSWLHFYRTAASSPLL---DLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDG 338
              DLS  H   T+++  L     L++      +L N +   S S+S   + H +  +T+ 
Sbjct: 1844 SLDLS--HGVHTSSAGTLATDRSLNTGVTRASRLENGSDTSSKSLSMGNSTHTSMTYTEK 1901

Query: 339  GPRTLRSLTVSLGPVSKTEGFPKDSRIATT------SSSVLLSPSAVESRRNSRVTGNPG 392
                   ++ S+ P  +T     ++ + +T      S ++  S   VE   ++ +T  P 
Sbjct: 1902 S-----EVSSSIHPRPETSAPGAETTLTSTPGNRAISLTLPFSSIPVEEVISTGITSGPD 1956

Query: 393  DEEFIEPSTENEFGLTSLRWQNDSPTFGEHQLASSSEVQNGSPMSQTETVSRSVAPMRGG 452
                  P T +     ++ W +        Q   +   +  S  +Q+     SVA     
Sbjct: 1957 INS--APMTHSPITPPTIVWTSTGTIEQSTQPLHAVSSEKVSVQTQSTPYVNSVA----- 2009

Query: 453  EITAHWLLTNSTTSADVTGSSASYPEGVNASVLTQFSDSTVQSGGSHTA-LGDRSYSESS 511
             ++A     NS +S    GSS S P    +S   +  DST+    + T+ L D + S  +
Sbjct: 2010 -VSASPTHENSVSS----GSSTSSPY---SSASLESLDSTISRRNAITSWLWDLTTSLPT 2061

Query: 512  STSSSESLNSSAPRGERSIAGISYGQVRGTAIEQRTSSDHTDHTYLSSTFTKGERALLSI 571
            +T  S SL+ +   G   ++  S            ++S          T T G +   + 
Sbjct: 2062 TTWPSTSLSEALSSGHSGVSNPSSTTTEFPLFSAASTSAAKQRN--PETETHGPQNTAAS 2119

Query: 572  TDNSSSSDIVESSTSYIKISNSSHSEYSSFFHAQTERSNISSYDGEYAQPSTESPVLHTS 631
            T N+ +S +   S + +  S SS         A T RS++S    E    ST +P L T+
Sbjct: 2120 TLNTDASSVTGLSETPVGASISSEVPLPM---AITSRSDVSGLTSE----STANPSLGTA 2172

Query: 632  NLPS--YTPTINMPNTSVVLD---------TDAEFVSDSSSSSSSSSSSSSSGPP----- 675
            +      T TI++P +  ++                S  ++++ +S   +S+GPP     
Sbjct: 2173 SSAGTKLTRTISLPTSESLVSFRMNKDPWTVSIPLGSHPTTNTETSIPVNSAGPPGLSTV 2232

Query: 676  ----LPLPSVSQSHHLFSSILPSTRASV----HLLKSTSDASTPWSSSPSPLPVSLTTST 727
                +  PS         S  PS    V    H  + T+ +    SS    L   +T   
Sbjct: 2233 ASDVIDTPSDGAESIPTVSFSPSPDTEVTTISHFPEKTTHSFRTISSLTHELTSRVTPIP 2292

Query: 728  SAPLSVSQTTLPQSSSTPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADLKSQSTPHQE 787
               +S + +T P  +S  +    R T  ++  T++          + T  L +++T    
Sbjct: 2293 GDWMSSAMSTKPTGASPSITLGERRTITSAAPTTSPIVLTASFTETSTVSLDNETTVKTS 2352

Query: 788  KVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESSTEQTLPAT--STNLAQMSPTFTTT 845
             ++   K+  L S  + S+  + T      S+  S+ + T  A+   T+++ M+ + + +
Sbjct: 2353 DILDARKTNELPSDSSSSSDLINT------SIASSTMDVTKTASISPTSISGMTASSSPS 2406

Query: 846  ILKTSQPLM----------TTPGTLSSTASLVTGPIAVQTTAG-KQLSLTHP-EILVPQI 893
            +  + +P +          T+P   S+T SL  G     T +     ++THP E     +
Sbjct: 2407 LFSSDRPQVPTSTTETNTATSPSVSSNTYSLDGGSNVGGTPSTLPPFTITHPVETSSALL 2466

Query: 894  STEGGISTERNRVIVDATTGLIP------LTSVPTSAKEMTTKLGVTAEYSPASRSLGTS 947
            +    + T    V  D  +G  P      +TSVP  A    T +G T +  PA   L TS
Sbjct: 2467 AWSRPVRTFSTMVSTDTASGENPTSSNSVVTSVP--APGTWTSVGSTTDL-PAMGFLKTS 2523

Query: 948  PSPQ--TTVVSTAE-----------------------DLAPKSATFAVQSSTQSPTTVSS 982
            P+ +  + + ST E                        L   S + A+ SS Q+PTT +S
Sbjct: 2524 PAGEAHSLLASTIEPATAFTPHLSAAVVTGSSATSEASLLTTSESKAIHSSPQTPTTPTS 2583

Query: 983  SASVNSCA 990
             A+  + A
Sbjct: 2584 GANWETSA 2591



 Score = 80.9 bits (198), Expect = 8e-15
 Identities = 211/956 (22%), Positives = 357/956 (37%), Gaps = 156/956 (16%)

Query: 26    AAPGTRDPPPSPARRALS--LAPLAGAGLELQLERRPEREPPPTPPRERRGPATPGP--- 80
             A   +R   P PA+  +S   +      +   L R+   +   TP     G  + G    
Sbjct: 9325  AISSSRTSIPGPAQSTMSSDTSMETITRISTPLTRKESTDMAITPKTGPSGATSQGTFTL 9384

Query: 81    --SYRAPEPG---AATQRGPSGRAPRGGSADAAWKHWPESNTEAHVENITFYQNQEDFST 135
               S  A  PG   A TQR P        S       WP   +   VE  +   +    S+
Sbjct: 9385  DSSSTASWPGTHSATTQRFPQSVVTTPMSRGPEDVSWP---SPLSVEKNSPPSSLVSSSS 9441

Query: 136   VSSKEGVMVQTSGKSHAASDAPENLTLLAETADARGRSGSSSRTNFTILPVGYSLEIATA 195
             V+S   +    SG SH+ S  P      +    A     +S     T  P   ++    +
Sbjct: 9442  VTSPSPLYSTPSGSSHS-SPVPVTSLFTSIMMKATDMLDASLEPETTSAP-NMNITSDES 9499

Query: 196   LTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTASEMGTERAMGLSEEWTVHSQEATT 255
             L +      +E++H+        E  AA   ++ +A+E     + G SE   V S   T+
Sbjct: 9500  LAASKATTETEAIHV-------FENTAASHVETTSATEELYSSSPGFSEPTKVISPVVTS 9552

Query: 256   SAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASSPLLDLSSSSESTEKLNNS 315
             S+   + +     G       +  S       L   RT+      D++SS+E++  L   
Sbjct: 9553  SSIRDNMVSTTMPGSSGITRIEIESMSSLTPGLRETRTSQ-----DITSSTETSTVLYKM 9607

Query: 316   TGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVSKTEGFPKDSRIATTSSSVLLS 375
                 +  VS+T+ M  +     G  ++  SL +S   V++    P    I T S+ + ++
Sbjct: 9608  PSGATPEVSRTEVMPSSRTSIPGPAQSTMSLDISDEVVTRLSTSP----IMTESAEITIT 9663

Query: 376   PSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQNDSPTFGEHQLASSSEVQNGSP 435
                  S   S+VT   G               TS+ + +     G H           S 
Sbjct: 9664  TQTGYSLATSQVTLPLG---------------TSMTFLS-----GTH-----------ST 9692

Query: 436   MSQTETVSRSVAPMRGGEITAHWLLTNSTTSADVTGSSASYPEGVNASVLTQFSDSTVQS 495
             MSQ  + S     M  G  +  W    S    + T SS+S         LT    +T   
Sbjct: 9693  MSQGLSHSEMTNLMSRGPESLSW---TSPRFVETTRSSSS---------LTSLPLTT--- 9737

Query: 496   GGSHTALGDRSYSESSSTSSSESLNSSAPRGERSIAG-ISYGQVRGTAIEQRTSSDHTDH 554
                       S S  SST    S +S  P     + G +   +V  T+ E +TSS     
Sbjct: 9738  ----------SLSPVSSTLLDSSPSSPLPVTSLILPGLVKTTEVLDTSSEPKTSSSPN-- 9785

Query: 555   TYLSSTFTKGERALLSITDNSSSSDIVESSTSYIKISNSSHSEYSSFFHAQTERSNISSY 614
               LSST  +       +TD         ++ + ++ S+S H  +SS          I S 
Sbjct: 9786  --LSSTSVEIPATSEIMTDTEKIHPSSNTAVAKVRTSSSVHESHSSVLADSETTITIPSM 9843

Query: 615   DGEYAQPSTESPVLHTSNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSGP 674
                 A   T    + TSN P+++ T  +P       T      ++S+S  ++S + +S  
Sbjct: 9844  GITSAVDDT---TVFTSN-PAFSETRRIPTEPTFSLTPG--FRETSTSEETTSITETSAV 9897

Query: 675   PLPLPSVSQSHHLFSSILPSTRASVHLLKSTSDASTP------------WSSSPSPLPVS 722
                +P+ + +    + I+ S R  +H+  S     +P             S       ++
Sbjct: 9898  LYGVPTSATTEVSMTEIMSSNR--IHIPDSDQSTMSPDIITEVITRLSSSSMMSESTQMT 9955

Query: 723   LTTSTSAPLSVSQTTLPQSSSTPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADLKSQS 782
             +TT  S+P + +Q+TL  +++T  L R   T    F  S MT+ M+   S +    KS  
Sbjct: 9956  ITTQKSSPGATAQSTLTLATTTAPLARTHSTVPPRFLHSEMTTLMS--RSPENPSWKSSL 10013

Query: 783   TPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESSTEQTLPATSTNLAQMSPTF 842
                   V   S S SL+SLP  ++ +V++  P           Q++P++S ++  +    
Sbjct: 10014 F-----VEKTSSSSSLLSLPVTTSPSVSSTLP-----------QSIPSSSFSVTSL---L 10054

Query: 843   TTTILKTSQPLMTTPGTLSSTASLVTGPIAVQTTAGKQLSLTHPEILVPQISTEGGISTE 902
             T  ++KT+    T PG                T+    LS T  EIL    ++E    TE
Sbjct: 10055 TPGMVKTTD-TSTEPG----------------TSLSPNLSGTSVEILA---ASEVTTDTE 10094

Query: 903   RNRVIVDATTGLIPLTSVPTSAKEMTTKLGVTAEYSPASRSLGTSPSPQTTVVSTA 958
             +   I  +++  +      +S  E+ + + + +E S A+  +GT  S   T +ST+
Sbjct: 10095 K---IHPSSSMAVTNVGTTSSGHELYSSVSIHSEPSKATYPVGTPSSMAETSISTS 10147



 Score = 79.7 bits (195), Expect = 2e-14
 Identities = 197/900 (21%), Positives = 365/900 (40%), Gaps = 121/900 (13%)

Query: 178  RTNFTILPVGYSLEIATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTASEMGTE 237
            +T  T +P+  ++E  T  ++  G+ ++   HLP+ ++          TKS T + + TE
Sbjct: 3230 KTPETTVPMETTVEPVTLQSTALGSGSTSISHLPTGTTS--------PTKSPTENMLATE 3281

Query: 238  RAMGLS----EEWT---------VHSQEATTSAWS---PSFLPALEMGELTTPSRKRNSS 281
            R + LS    E WT              AT S+ S   P+       G+ ++P     ++
Sbjct: 3282 R-VSLSPSPPEAWTNLYSGTPGGTRQSLATMSSVSLESPTARSITGTGQQSSPELVSKTT 3340

Query: 282  GPDLSWLHFYRTAASSPL-LDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGP 340
            G + S  H      +    + LS+SS   E    S    SS   ++K      V T   P
Sbjct: 3341 GMEFSMWHGSTGGTTGDTHVSLSTSSNILEDPVTSPNSVSSLTDKSKHKTETWVSTTAIP 3400

Query: 341  RTLRSLTVSLGPV----SKTEGFPKDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEF 396
             T+ +  +         S  E +   S  +  +S   ++  A     N+    +      
Sbjct: 3401 STVLNNKIMAAEQQTSRSVDEAYSSTSSWSDQTSGSDITLGASPDVTNTLYITSTAQTTS 3460

Query: 397  IEPSTENEFGLTSLRWQNDSPTFGEHQLASSSEVQNGSPMSQTETVSRSVAPMRG--GEI 454
            +      + G+TSL     +P+ G+   ASS      SP    ET+  +V+ ++      
Sbjct: 3461 LVSLPSGDQGITSLT----NPSGGKTSSASSVT----SPSIGLETLRANVSAVKSDIAPT 3512

Query: 455  TAHWLLTNSTTSADVTGSSASYPEGVNASVLTQFSDS------TVQSGGSHTALGDRSYS 508
              H   T+S     +   + +   G++ ++ T  ++S        + G S       +  
Sbjct: 3513 AGHLSQTSSPAEVSILDVTTAPTPGISTTITTMGTNSISTTTPNPEVGMSTMDSTPATER 3572

Query: 509  ESSSTSSSESLNSSAPRGERSI----AGISYGQVRGTAIEQRTSSDHTDHTYLSSTFTKG 564
             ++ST    + +S+A     ++    + +   +  GT     T+S     T L S  T  
Sbjct: 3573 RTTSTEHPSTWSSTAASDSWTVTDMTSNLKVARSPGTISTMHTTSFLASSTELDSMSTPH 3632

Query: 565  ERALLS----ITDNSSSSDI-VESSTSYIKISNS---SHSEYSSFFHAQTERSNISSYD- 615
             R  +     +T +S +S +  E+STS   +S S   + +  S+F  ++ +R +IS  D 
Sbjct: 3633 GRITVIGTSLVTPSSDASAVKTETSTSERTLSPSDTTASTPISTF--SRVQRMSISVPDI 3690

Query: 616  --GEYAQPSTES---PVLHTSNLPSYTPTI-NMPNTSVVLDTDAEFVSDSSSSSSSSSSS 669
                +   STE+   PV   S   + T T  N P ++ + D+ +    D+  S SS++++
Sbjct: 3691 LSTSWTPSSTEAEDVPVSMVSTDHASTKTDPNTPLSTFLFDSLSTLDWDTGRSLSSATAT 3750

Query: 670  SSSGPPLPLPSVSQSHHLFSSILPSTRASVHLLKSTSDASTPWSSSPS-------PLPVS 722
            +S+      P   Q   L + I P+T      +   + A TP + + S       P P S
Sbjct: 3751 TSAPQGATTP---QELTLETMISPATSQLPFSIGHITSAVTPAAMARSSGVTFSRPDPTS 3807

Query: 723  LT---TSTSAPLSVSQTT--LPQSSSTP--VLPRARETPVTSFQTSTMTSFMTMLH-SSQ 774
                 TST  P + S     +P+S++T   V+P   +TP  +FQ    T+  T    +S 
Sbjct: 3808 KKAEQTSTQLPTTTSAHPGQVPRSAATTLDVIPHTAKTPDATFQRQGQTALTTEARATSD 3867

Query: 775  TADLKSQSTPHQEKV--ITESKSPSLVSLPTESTKAVTTNSPLPPSLTESSTEQTLPATS 832
            + + K +STP    +  +  S S   +   T S+  + T + L  +L ES T  +    S
Sbjct: 3868 SWNEKEKSTPSAPWITEMMNSVSEDTIKEVTSSSSVLRTLNTLDINL-ESGTTSSPSWKS 3926

Query: 833  TNLAQMSPTFTTTILKTSQP---LMTTPGTLSSTASLVTGPIAVQTTAGKQLSLTHPEIL 889
            +   +++P+ +TT  +   P    + T G ++S+       I   + + K   LT P + 
Sbjct: 3927 SPYERIAPSESTTDKEAIHPSTNTVETTGWVTSSEHASHSTIPAHSASSK---LTSPVV- 3982

Query: 890  VPQISTEGGISTERNRVIVDATTGLIPLTSVPTSAKEMTTKLG-VTAEYSPASRSLGTSP 948
                      ++ R + IV  +T     T+ P S +  T     +T E    S  + TS 
Sbjct: 3983 ---------TTSTREQAIVSMST-----TTWPESTRARTEPNSFLTIELRDVSPYMDTSS 4028

Query: 949  SPQTTVVSTAEDLAPKSATFAVQSSTQSP-TTVSSSASVNSCAVNPCLHNGECVADNTSR 1007
            + QT+++S+    A           T+ P T ++SS  ++S  +   + + +  ++  +R
Sbjct: 4029 TTQTSIISSPGSTA----------ITKGPRTEITSSKRISSSFLAQSMRSSDSPSEAITR 4078



 Score = 79.7 bits (195), Expect = 2e-14
 Identities = 170/697 (24%), Positives = 272/697 (39%), Gaps = 112/697 (16%)

Query: 347  TVSLGPVSKTEGFPKDSRIATTSSSVL--LSPSAVESRR----NSRVTGNPGDEEFIEPS 400
            T SL    K     +D  ++T  S+VL  L+  A E+ R    +SR T  PG +     S
Sbjct: 6652 TFSLAHGLKGTSTSQDPIVSTEKSAVLHKLTTGATETSRTEVASSRRTSIPGPDH----S 6707

Query: 401  TENEFGLTSLRWQNDSPTFGEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLL 460
            TE             SP     ++  S  +  G   S   T+     P  G      + L
Sbjct: 6708 TE-------------SPDIST-EVIPSLPISLGITESSNMTIITRTGPPLGSTSQGTFTL 6753

Query: 461  TNSTTSADVTGSSASYPEGVNASVLTQFS-DSTVQSGGSHTALGDRSYSES---SSTSSS 516
               TTS+     S +  E  ++ + T  + D  + S     ++   S+S S   S   +S
Sbjct: 6754 DTPTTSSRAGTHSMATQEFPHSEMTTVMNKDPEILSWTIPPSIEKTSFSSSLMPSPAMTS 6813

Query: 517  ESLNSSAPRGERSIAG----------ISYGQVRGTAIEQRTSSDHTDHTYLSSTFTKGER 566
              ++S+ P+   +             +      GT+ E  TSS       LSST      
Sbjct: 6814 PPVSSTLPKTIHTTPSPMTSLLTPSLVMTTDTLGTSPEPTTSSPPN----LSST----SH 6865

Query: 567  ALLSITDNSSSSDIVESSTSY----IKISNSSHSEYSSFFHAQTERSNISSYDGEYAQPS 622
             +L+  +++++ + +  STS     ++ ++S H   SS   A +E++  +      A   
Sbjct: 6866 EILTTDEDTTAIEAMHPSTSTAATNVETTSSGHGSQSSVL-ADSEKTKAT------APMD 6918

Query: 623  TESPVLHTS-----NLPSYTPTINMPNT-SVVLDTDAEFVSDSSSSSSSSSSSSSSGPPL 676
            T S + HT+     ++ S T  I   +T S+        +S ++S S+ +S   S  P  
Sbjct: 6919 TTSTMGHTTVSTSMSVSSETTKIKRESTYSLTPGLRETSISQNASFSTDTSIVLSEVPTG 6978

Query: 677  PLPSVSQSHHLFS--SILPSTRASVHLLKSTSDASTPWSSSPS---PLPVSLTTSTSAPL 731
                VS++    S  + +P    S  L + ++   T   +SP+      +++ T T    
Sbjct: 6979 TTAEVSRTEVTSSGRTSIPGPSQSTVLPEISTRTMTRLFASPTMTESAEMTIPTQTGPSG 7038

Query: 732  SVSQTTLP-QSSSTPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVI 790
            S SQ TL   +S+T    +   T    F  S MT+ M    S    D+  QS+P  E   
Sbjct: 7039 STSQDTLTLDTSTTKSQAKTHSTLTQRFPHSEMTTLM----SRGPGDMSWQSSPSLEN-- 7092

Query: 791  TESKSPSLVSLPTESTKAVTTNSPLPPSLTESSTEQTLPATSTNLAQMSPTFTTTILKTS 850
              S  PSL+SLP        T SP P S T   T  + P   T+L   SP  TT +L TS
Sbjct: 7093 -PSSLPSLLSLPA-------TTSPPPISSTLPVTISSSPLPVTSLLTSSPVTTTDMLHTS 7144

Query: 851  QPLMT-TPGTLSSTAS--LVTGPIAVQTTAGKQLSLTHPEILVPQISTEGGISTER--NR 905
              L+T +P  LS T+   L TG     T A       HP       + E   S     + 
Sbjct: 7145 PELVTSSPPKLSHTSDERLTTGKDTTNTEA------VHPSTNTAASNVEIPSSGHESPSS 7198

Query: 906  VIVDATTGLIPLTSVPTSAKEMTTKLGVTAEYSPASR------------------SLGTS 947
             + D+ T         TS +E TT    T  +   SR                  S+ TS
Sbjct: 7199 ALADSETSKATSPMFITSTQEDTTVAISTPHFLETSRIQKESISSLSPKLRETGSSVETS 7258

Query: 948  PSPQTTVVSTAEDLAPKSATFAVQSSTQSPTTVSSSA 984
             + +T+ V +   +   +     + ++ S T++S SA
Sbjct: 7259 SAIETSAVLSEVSIGATTEISRTEVTSSSRTSISGSA 7295



 Score = 79.7 bits (195), Expect = 2e-14
 Identities = 233/1107 (21%), Positives = 421/1107 (38%), Gaps = 180/1107 (16%)

Query: 31   RDPPPSPARRALS--LAPLAGAGLELQLERRPEREPPPTPPRERRGPATPGP-----SYR 83
            R   P PA+  +S  ++      +   L      E   TP     G ++ G      S R
Sbjct: 8750 RTSTPGPAQSTISPEISTETITRISTPLTTTGSAEMTITPKTGHSGASSQGTFTLDTSSR 8809

Query: 84   APEPG---AATQRGP-SGRAP--RGGSADAAWKHWPESNTEAHVENITFYQNQEDFSTVS 137
            A  PG   AAT R P SG       G  D +W   P       VE  +   +    S V+
Sbjct: 8810 ASWPGTHSAATHRSPHSGMTTPMSRGPEDVSWPSRPS------VEKTSPPSSLVSLSAVT 8863

Query: 138  SKEGVMVQTSGKSHAASDAPENL--TLLAETADARGRSGSSSRTNFTILPVGYSLEIATA 195
            S   +    S  SH++     +L   ++ +T D       +S    T  P   ++    +
Sbjct: 8864 SPSPLYSTPSESSHSSPLRVTSLFTPVMMKTTDML----DTSLEPVTTSPPSMNITSDES 8919

Query: 196  LTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTASEMGTERAMGLSEEWTVHSQEATT 255
            L +    + +E++ L        E  A  Q  + +A +       GL E   V S   T+
Sbjct: 8920 LATSKATMETEAIQL-------SENTAVTQMGTISARQEFYSSYPGLPEPSKVTSPVVTS 8972

Query: 256  SAWSP---SFLPA--------LEMGELTTPSRKRNSSGPDLSWLHFYRTAASSPLLDLSS 304
            S       + +PA        +E     TP+ +  S+  ++       T     L   + 
Sbjct: 8973 STIKDIVSTTIPASSEITRIEMESTSTLTPTPRETSTSQEIHSATKPSTVPYKALTSATI 9032

Query: 305  SSESTEKLNNSTGLQ--SSSVSQTKTMHVAT------VFTDGGPRTLRSLTVSLGPVSKT 356
                T+ +++S G     S++SQ  +  V T      + T+    T+ + T S G  S+ 
Sbjct: 9033 EDSMTQVMSSSRGPSPDQSTMSQDISTEVITRLSTSPIKTESTEMTITTQTGSPGATSRG 9092

Query: 357  EGFPKDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIE-PSTEN----EFGLTSLR 411
                  S    + +    S     S+  + ++  PGD  ++  PS E      F L+S  
Sbjct: 9093 TLTLDTSTTFMSGTHSTASQGFSHSQMTALMSRTPGDVPWLSHPSVEEASSASFSLSSPV 9152

Query: 412  WQNDSPTFGE------------------------HQLASSSEVQNGSPMSQTETVSRSVA 447
              + SP                              L +SSE +  SP + + T +  +A
Sbjct: 9153 MTSSSPVSSTLPDSIHSSSLPVTSLLTSGLVKTTELLGTSSEPETSSPPNLSSTSAEILA 9212

Query: 448  PMRGGEITAHWLLTNSTTS-----------ADVTGSSA------SYPEGVNASVLTQ--- 487
                   T    +TN  TS           AD   + A      +YP G + +VLT    
Sbjct: 9213 ITEVTTDTEKLEMTNVVTSGYTHESPSSVLADSVTTKATSSMGITYPTG-DTNVLTSTPA 9271

Query: 488  FSD-STVQSGGSHT---ALGDRSYSESSSTSSSES-LNSSAPRGERS----IAGISYGQV 538
            FSD S +Q+    +    L + S SE +S+++ +S + SS P G  +       IS  + 
Sbjct: 9272 FSDTSRIQTKSKLSLTPGLMETSISEETSSATEKSTVLSSVPTGATTEVSRTEAISSSRT 9331

Query: 539  RGTAIEQRTSSDHTDH---TYLSSTFTKGERALLSITDNSSSSDIVESSTSYIKISNS-- 593
                  Q T S  T     T +S+  T+ E   ++IT  +  S      T  +  S++  
Sbjct: 9332 SIPGPAQSTMSSDTSMETITRISTPLTRKESTDMAITPKTGPSGATSQGTFTLDSSSTAS 9391

Query: 594  ---SHSEYSSFFHAQTERSNISSYDGEYAQP--------STESPVLHTSNLPSYTPTINM 642
               +HS  +  F      + +S    + + P        S  S ++ +S++ S +P  + 
Sbjct: 9392 WPGTHSATTQRFPQSVVTTPMSRGPEDVSWPSPLSVEKNSPPSSLVSSSSVTSPSPLYST 9451

Query: 643  PN--------------TSVVLDT----DAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQS 684
            P+              TS+++      DA    +++S+ + + +S  S       + +++
Sbjct: 9452 PSGSSHSSPVPVTSLFTSIMMKATDMLDASLEPETTSAPNMNITSDESLAASKATTETEA 9511

Query: 685  HHLFSSILPSTRASVHLLKSTSD--ASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQSS 742
             H+F +   +  + V    +T +  +S+P  S P+ +   + TS+S   ++  TT+P SS
Sbjct: 9512 IHVFEN---TAASHVETTSATEELYSSSPGFSEPTKVISPVVTSSSIRDNMVSTTMPGSS 9568

Query: 743  S---------TPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITES 793
                      + + P  RET  TS   ++ T   T+L+      + S +TP   +     
Sbjct: 9569 GITRIEIESMSSLTPGLRETR-TSQDITSSTETSTVLYK-----MPSGATPEVSRTEVMP 9622

Query: 794  KSPSLVSLPTESTKA------VTTNSPLPPSLTESS----TEQTLPATSTNLAQMSPTFT 843
             S + +  P +ST +      V T     P +TES+    T QT  + +T+   +    +
Sbjct: 9623 SSRTSIPGPAQSTMSLDISDEVVTRLSTSPIMTESAEITITTQTGYSLATSQVTLPLGTS 9682

Query: 844  TTILKTSQPLMTTPGTLSSTASLVT-GPIAVQTTAGKQLSLTHPEILVPQISTEGGISTE 902
             T L  +   M+   + S   +L++ GP ++  T+ + +  T     +  +     +S  
Sbjct: 9683 MTFLSGTHSTMSQGLSHSEMTNLMSRGPESLSWTSPRFVETTRSSSSLTSLPLTTSLSPV 9742

Query: 903  RNRVIVDATTGLIPLTSVPTSAKEMTTKLGVTAEYSPASRSLGTSPS----PQTTVVST- 957
             + ++  + +  +P+TS+       TT++  T+     S S   S +    P T+ + T 
Sbjct: 9743 SSTLLDSSPSSPLPVTSLILPGLVKTTEVLDTSSEPKTSSSPNLSSTSVEIPATSEIMTD 9802

Query: 958  AEDLAPKSATFAVQSSTQSPTTVSSSA 984
             E + P S T   +  T S    S S+
Sbjct: 9803 TEKIHPSSNTAVAKVRTSSSVHESHSS 9829



 Score = 77.8 bits (190), Expect = 7e-14
 Identities = 199/836 (23%), Positives = 312/836 (37%), Gaps = 123/836 (14%)

Query: 193  ATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTASEMGTERAMGLSEEWTVHSQ- 251
            ATA +  S +L   +  +P S S      A  +T +G++   GT+ +      +T+ S  
Sbjct: 630  ATASSETSADLTLATNGVPVSVSP-----AVSKTAAGSSPPGGTKPS------YTMVSSV 678

Query: 252  -EATTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASSPLLDLSSSSESTE 310
               T+S  S +F     +G LT  + +   S P+       + + S PLL  SS+S   +
Sbjct: 679  IPETSSLQSSAFREGTSLG-LTPLNTRHPFSSPEPDSAGHTKISTSIPLL--SSASVLED 735

Query: 311  KLNNSTGLQSSSVSQTKTMHVATVFTDGGPRT--LRSLTVSLGPVSKTE--------GFP 360
            K++ ++       + + T     + T   P +  L S+T+S    S             P
Sbjct: 736  KVSATSTFSHHKATSSITTGTPEISTKTKPSSAVLSSMTLSNAATSPERVRNATSPLTHP 795

Query: 361  KDSRIATTSSSVLLSPSA-VESRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQNDSPTF 419
              S   T  S + LS SA      N   TG    E    PST +   ++ ++    S T 
Sbjct: 796  SPSGEETAGSVLTLSTSAETTDSPNIHPTGTLTSESSESPSTLSLPSVSGVKTTFSSSTP 855

Query: 420  GEHQLASSSEVQNGS--PMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADVTGSSASYP 477
              H   S  E +  S   +SQ ET   SV+ +R             TT A  +  +  +P
Sbjct: 856  STHLFTSGEETEETSNPSVSQPET---SVSRVR-------------TTLASTSVPTPVFP 899

Query: 478  EGVNASVLTQFSDSTVQSGGSHTALGDRSYSESSSTSSSESLNSSAPRGERSIAGISYGQ 537
                   +  +   + Q   SH     R+   +SSTS + S  S+ P+        +  Q
Sbjct: 900  ------TMDTWPTRSAQFSSSHLVSELRA---TSSTSVTNSTGSALPKISHLTGTATMSQ 950

Query: 538  VRGTAIEQRTSSDHTDHTYLSSTFTKGERALLSITDNSSSSDIVESSTSYIKISNSSHSE 597
                      +   T     S  F  G  +  +    S++S       S      +S  E
Sbjct: 951  TNRDTFNDSAAPQSTTWPETSPRFKTGLPSATTTVSTSATSLSATVMVSKFTSPATSSME 1010

Query: 598  YSSFFHAQTE--RSNISSYDGEYAQPSTESPV---------LHTSNLPSYTPTINMPNTS 646
             +S     T    +  ++  G  A  ST  P+         L TS+LP  T   +   TS
Sbjct: 1011 ATSIREPSTTILTTETTNGPGSMAVASTNIPIGKGYITEGRLDTSHLPIGTTASS--ETS 1068

Query: 647  VVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVS----QSHHLFSSILPSTRASVHLL 702
            +      E VS S S S S  ++ SS P      V       +HL S  +   R      
Sbjct: 1069 MDFTMAKESVSMSVSPSQSMDAAGSSTPGRTSQFVDTFSDDVYHLTSREITIPR------ 1122

Query: 703  KSTSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQSSSTPVLPRARETPVTSFQTST 762
              TS A TP  ++  P        +  P S   T L   SS+P  P  + T  ++F T  
Sbjct: 1123 DGTSSALTPQMTATHP-------PSPDPGSARSTWLGILSSSPSSPTPKVTMSSTFSTQR 1175

Query: 763  MTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPL---PPSL 819
            +T+ M M     T +    + P+     T S +PS  ++PT      +T  PL    P+ 
Sbjct: 1176 VTTSMIM----DTVETSRWNMPNLPS--TTSLTPS--NIPTSGAIGKSTLVPLDTPSPAT 1227

Query: 820  TESSTEQTLPATSTNLAQMSPTFTTTILKTSQPLMTTPGTLSSTASLVTGPIAVQTTAGK 879
            +  ++E  LP  ST       T T +I   +     +P T+  T + V  P       G 
Sbjct: 1228 SLEASEGGLPTLST---YPESTNTPSIHLGAHASSESPSTIKLTMASVVKP-------GS 1277

Query: 880  QLSLTHPEILVPQISTEGGISTERNRVIVDATTGLIPLTSVP-----TSAKEMTTKLGVT 934
               LT      P I T   +ST R    +  ++G  P  + P      S  + TT +  T
Sbjct: 1278 YTPLT-----FPSIETHIHVSTAR----MAYSSGSSPEMTAPGETNTGSTWDPTTYITTT 1328

Query: 935  AEYSPASRSLGTSPSPQTTVVSTAEDLAPKSATFAVQSSTQSPTTVSSSASVNSCA 990
                 +S  + T P    T+ +T      +SAT A  S +     +SSS ++ S A
Sbjct: 1329 DPKDTSSAQVST-PHSVRTLRTTENHPKTESATPAAYSGSPK---ISSSPNLTSPA 1380



 Score = 75.9 bits (185), Expect = 3e-13
 Identities = 177/833 (21%), Positives = 303/833 (36%), Gaps = 159/833 (19%)

Query: 247  TVHSQEAT-TSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASSPLLDLSSS 305
            T+H+  +  TS  +PS +   +   L T      SS P+LS       + S  +L     
Sbjct: 6823 TIHTTPSPMTSLLTPSLVMTTDT--LGTSPEPTTSSPPNLS-------STSHEILTTDED 6873

Query: 306  SESTEKLNNSTGLQSSSVSQTKTMH--VATVFTDGGPRTLRSLTVSLGPVSKTEGFPKDS 363
            + + E ++ ST   +++V  T + H   ++V  D         T +  P+  T       
Sbjct: 6874 TTAIEAMHPSTSTAATNVETTSSGHGSQSSVLADS------EKTKATAPMDTTSTMGH-- 6925

Query: 364  RIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQNDSPTFGEHQ 423
               T S+S+ +S    + +R S  +  PG  E    S    F   +    ++ PT    +
Sbjct: 6926 --TTVSTSMSVSSETTKIKRESTYSLTPGLRE-TSISQNASFSTDTSIVLSEVPTGTTAE 6982

Query: 424  LASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADVTGSSASYPEG-VNA 482
            ++ +    +G       + S  +  +    +T  +     T SA++T  + + P G  + 
Sbjct: 6983 VSRTEVTSSGRTSIPGPSQSTVLPEISTRTMTRLFASPTMTESAEMTIPTQTGPSGSTSQ 7042

Query: 483  SVLTQFSDSTVQSGGSHTAL-----------------GDRSYSESSSTSSSESL------ 519
              LT  + +T     +H+ L                 GD S+  S S  +  SL      
Sbjct: 7043 DTLTLDTSTTKSQAKTHSTLTQRFPHSEMTTLMSRGPGDMSWQSSPSLENPSSLPSLLSL 7102

Query: 520  ---NSSAPRGERSIAGISYGQVRGTAIEQRTSSDHTDHTYLSSTFTKGERALLSITDN-- 574
                S  P        IS   +  T++   +    TD  + S          LS T +  
Sbjct: 7103 PATTSPPPISSTLPVTISSSPLPVTSLLTSSPVTTTDMLHTSPELVTSSPPKLSHTSDER 7162

Query: 575  ------SSSSDIVESST----SYIKISNSSHSEYSS--------------FFHAQTERSN 610
                  +++++ V  ST    S ++I +S H   SS              F  +  E + 
Sbjct: 7163 LTTGKDTTNTEAVHPSTNTAASNVEIPSSGHESPSSALADSETSKATSPMFITSTQEDTT 7222

Query: 611  ISSYDGEYAQPSTESPVLHTSNLPSYTPTINMPNTSVVLDTDAEF----------VSDSS 660
            ++     + + S       +S  P    T +   TS  ++T A            +S + 
Sbjct: 7223 VAISTPHFLETSRIQKESISSLSPKLRETGSSVETSSAIETSAVLSEVSIGATTEISRTE 7282

Query: 661  SSSSSSSSSSSSGPPLPLPSVSQSHHLFSSILPSTRASVHLLKSTSDASTPWSSSPSPLP 720
             +SSS +S S S     LP +S +  +     P++     +L  +S+             
Sbjct: 7283 VTSSSRTSISGSAESTMLPEISTTRKIIK--FPTS----PILAESSE------------- 7323

Query: 721  VSLTTSTSAPLSVSQTTLPQSSSTPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADLKS 780
            +++ T TS P S S++T    +ST        TP      STMT                
Sbjct: 7324 MTIKTQTSPPGSTSESTFTLDTST--------TPSLVITHSTMT---------------- 7359

Query: 781  QSTPHQEKVITESKS----PSLVSLPTESTKAVTTNSPLPPSLTESSTEQTLPATS---- 832
            Q  PH E     S+     P   SLP E T   ++   L   ++ S    TLPA+S    
Sbjct: 7360 QRLPHSEITTLVSRGAGDVPRPSSLPVEETSPPSSQLSLSAMISPSPVSSTLPASSHSSS 7419

Query: 833  ---TNLAQMSPTFTTTILKTS-QPLMTTPGTLSSTASLVTGPIAVQTTAGKQLSLTHP-- 886
               T+L       TT +L  S +P  ++P +LSST+  +     V T   K     HP  
Sbjct: 7420 ASVTSLLTPGQVKTTEVLDASAEPETSSPPSLSSTSVEILATSEVTTDTEK----IHPFS 7475

Query: 887  EILVPQISTEGGISTERNRVIVDATT-------GLIPL-----TSVPTSAKEMTTKLGVT 934
               V ++ T        + V+ D+ T       G I +      S  T A   T K+   
Sbjct: 7476 NTAVTKVGTSSSGHESPSSVLPDSETTKATSAMGTISIMGDTSVSTLTPALSNTRKIQSE 7535

Query: 935  AEYSPASRSLGTSPSPQTTVVSTAEDLAPKSATFAVQSSTQSPTTVSSSASVN 987
               S  +R   TS S +T++ + A  +  K +T A    +++     S  S++
Sbjct: 7536 PASSLTTRLRETSTSEETSLATEANTVLSKVSTGATTEVSRTEAISFSRTSMS 7588



 Score = 74.3 bits (181), Expect = 7e-13
 Identities = 176/806 (21%), Positives = 309/806 (38%), Gaps = 84/806 (10%)

Query: 211  PSSSSEFDERIAAFQTKSGTASEMGTERAMGLSEEWTVHSQEATTSAWSPSFLPALEMGE 270
            P   S    RI+     S +AS +  + +     E ++ S ++ TS  SP    A     
Sbjct: 268  PEPGSAGHSRISTSAPLSSSASVLDNKIS-----ETSIFSGQSLTSPLSPGVPEA----- 317

Query: 271  LTTPSRKRNSSGPDLSWLHFYRTAAS---SPLLDLSSSSESTEKLNNSTGLQSSSVSQTK 327
                S   NS+ P    L    T+A    S +  L + S ST K    T L   + ++T 
Sbjct: 318  --RASTMPNSAIPFSMTLSNAETSAERVRSTISSLGTPSIST-KQTAETILTFHAFAETM 374

Query: 328  TM---HVATVFTD---GGPRTLRSLTVS-LGPVSKTEGFPKDSRIATTSSSVLLSPSAVE 380
             +   H+A        G P TL   + S L   S +     +      S+S   +   + 
Sbjct: 375  DIPSTHIAKTLASEWLGSPGTLGGTSTSALTTTSPSTTLVSEETNTHHSTSGKETEGTLN 434

Query: 381  SRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQNDSPTFGEHQLASSSEVQNGSPMSQTE 440
            +      T  PG+E  +  +     G T+L          + ++ S S+V +  P  +  
Sbjct: 435  TSMTPLETSAPGEESEMTATLVPTLGFTTL----------DSKIRSPSQVSSSHPTRELR 484

Query: 441  TVSRSVAPMRGGEITAHWLLTNSTTSADVTGSSASYPEGVNASVLTQFSDSTVQSGGSHT 500
            T   S +  +     AH    +S      T S++      + S   QFS+    +    T
Sbjct: 485  TTG-STSGRQSSSTAAHG---SSDILRATTSSTSKASSWTSESTAQQFSEPQ-HTQWVET 539

Query: 501  ALGDRSYSESSSTSSSESLNSSAPRGERSIAGISYGQVRGTAIEQRTSSDHTDHTYLSST 560
            +   ++    +STS +  + +S P        +     +G  +E+ TS+D       +  
Sbjct: 540  SPSMKTERPPASTSVAAPITTSVPSVVSGFTTLKTSSTKGIWLEE-TSADTLIGESTAGP 598

Query: 561  FTKGERALLSITDNSSSSDIVESSTSYIKISNSSHSEYSSFFHAQTERSNISSYDGEYAQ 620
             T        I+    SS      T+++    ++ SE S+     T    +S        
Sbjct: 599  TTHQFAVPTGISMTGGSSTRGSQGTTHLLTRATASSETSADLTLATNGVPVSVSPAVSKT 658

Query: 621  PSTESPVLHTSNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPS 680
             +  SP   T   PSYT       +SV+ +T +   S     +S   +  ++  P   P 
Sbjct: 659  AAGSSPPGGTK--PSYTMV-----SSVIPETSSLQSSAFREGTSLGLTPLNTRHPFSSPE 711

Query: 681  V-SQSHHLFSSILPSTRASVHLLKSTSDAST-----PWSSSPSPLPVSLTTSTSAPLSVS 734
              S  H   S+ +P   ++  L    S  ST       SS  +  P   T +  +   +S
Sbjct: 712  PDSAGHTKISTSIPLLSSASVLEDKVSATSTFSHHKATSSITTGTPEISTKTKPSSAVLS 771

Query: 735  QTTLPQSSSTPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITE-- 792
              TL  ++++P   R   +P+T    S   +  ++L  S +A+       H    +T   
Sbjct: 772  SMTLSNAATSPERVRNATSPLTHPSPSGEETAGSVLTLSTSAETTDSPNIHPTGTLTSES 831

Query: 793  SKSPSLVSLPTESTKAVTTNSPLPPSLTESSTEQTLPATSTNLAQMSPTFT---TTILKT 849
            S+SPS +SLP+ S    T +S  P +   +S E+T   ++ +++Q   + +   TT+  T
Sbjct: 832  SESPSTLSLPSVSGVKTTFSSSTPSTHLFTSGEETEETSNPSVSQPETSVSRVRTTLAST 891

Query: 850  SQPLMTTPGTLSS----TASLVTGPIAVQTTAGKQLSLTHPE-ILVPQISTEGGIST--E 902
            S P    P T+ +    +A   +  +  +  A    S+T+     +P+IS   G +T  +
Sbjct: 892  SVPTPVFP-TMDTWPTRSAQFSSSHLVSELRATSSTSVTNSTGSALPKISHLTGTATMSQ 950

Query: 903  RNRVIVDAT----------------TGL-IPLTSVPTSAKEMTTKLGVTAEYSPASRSLG 945
             NR   + +                TGL    T+V TSA  ++  + V+   SPA+ S+ 
Sbjct: 951  TNRDTFNDSAAPQSTTWPETSPRFKTGLPSATTTVSTSATSLSATVMVSKFTSPATSSME 1010

Query: 946  TSP--SPQTTVVSTAEDLAPKSATFA 969
             +    P TT+++T     P S   A
Sbjct: 1011 ATSIREPSTTILTTETTNGPGSMAVA 1036



 Score = 74.3 bits (181), Expect = 7e-13
 Identities = 192/912 (21%), Positives = 347/912 (38%), Gaps = 126/912 (13%)

Query: 112  WPESNTEAHVENITFY----QNQEDFSTVSSKEGVMVQTSGKSHAASDAPENLTLLAETA 167
            WPES T A  E  +F     ++   +   SS     + +S  S A +  P       E  
Sbjct: 3999 WPES-TRARTEPNSFLTIELRDVSPYMDTSSTTQTSIISSPGSTAITKGPRT-----EIT 4052

Query: 168  DARGRSGS----SSRTNFTILPVGYSLEIATALTSQSGNLASESLHLPSSSSEFDERIAA 223
             ++  S S    S R++ +       L    A+T   G + +     P ++S     +  
Sbjct: 4053 SSKRISSSFLAQSMRSSDSPSEAITRLSNFPAMTESGGMILAMQTSPPGATSLSAPTLDT 4112

Query: 224  FQTKSGTASEMGTERAMGLSEEWTVHSQ-EATTSAWSPSFLPALEMGELTTPSRKRNSSG 282
              T S T + + T +    SE+ T+ S+    TS  SP             PS +  SS 
Sbjct: 4113 SATASWTGTPLATTQRFTYSEKTTLFSKGPEDTSQPSP-------------PSVEETSSS 4159

Query: 283  PDLSWLHFYRTAASSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRT 342
              L  +H   T+ S+ LL     S S+     S  L  +S    KT  ++ +  + G   
Sbjct: 4160 SSLVPIHA-TTSPSNILLTSQGHSPSSTPPVTSVFLSETS-GLGKTTDMSRISLEPGTSL 4217

Query: 343  LRSLTVSLGPVSKTEGFPKDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEP--- 399
              +L+ + G    T    +D++    S+   ++     S   S + G+    +   P   
Sbjct: 4218 PPNLSSTAGEALSTYEASRDTKAIHHSADTAVTNMEATSSEYSPIPGHTKPSKATSPLVT 4277

Query: 400  --------STENEFGLTSLRWQNDSPTFGEHQLASSSEVQNGSPMSQTETVSRSVAPMRG 451
                    S+ + FG +S   + ++ +     L   S  Q  S  ++T TV   V+    
Sbjct: 4278 SHIMGDITSSTSVFG-SSETTEIETVSSVNQGLQERSTSQVASSATETSTVITHVS---S 4333

Query: 452  GEITAHWLLTNSTTSADVTGSSASYPEGVNASVLTQFSDSTVQSGGSHTALGDRSYSESS 511
            G+ T H           VT + A++  G + S   QF  ST           D S + S+
Sbjct: 4334 GDATTH-----------VTKTQATFSSGTSISSPHQFITST-------NTFTDVSTNPST 4375

Query: 512  STSSSESLNSSAPRGERSIAGISYGQVRGTAIEQRTSSDHTDHTYLSST--FTKGERALL 569
            S   +ES   +      +  G +    +G  +   ++  +   T L+ T  F + E+  L
Sbjct: 4376 SLIMTESSGVTIT----TQTGPTGAATQGPYLLDTSTMPYLTETPLAVTPDFMQSEKTTL 4431

Query: 570  SITDNSSSSDIVESSTSYIKISNSSHSEYSSFFHAQTERSNISSYDGEYAQPSTESPVLH 629
                +    D+  S TS   ++ +S+    + F   T     S+  G++    T SPV  
Sbjct: 4432 I---SKGPKDV--SWTSPPSVAETSYPSSLTPFLVTTIPPATSTLQGQH----TSSPVSA 4482

Query: 630  TSNLPS-YTPTINMPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLF 688
            TS L S    T +M NTS+   T++    ++ S+   ++ ++++      PS++++    
Sbjct: 4483 TSVLTSGLVKTTDMLNTSMEPVTNSPQNLNNPSNEILATLAATTDIETIHPSINKAVTNM 4542

Query: 689  SSILPSTRASVHLLKSTSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQSSSTPVLP 748
                  T +S H+L ST             LPVS   ST+    V  +++  + ++  +P
Sbjct: 4543 G-----TASSAHVLHST-------------LPVSSEPSTATSPMVPASSMGDALASISIP 4584

Query: 749  RARETPVTSFQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKA 808
             +  T +    TS++T+        + + L+  ++  +  +I  + S   ++  T+    
Sbjct: 4585 GSETTDIEGEPTSSLTA-----GRKENSTLQEMNSTTESNIILSNVSVGAITEATKMEVP 4639

Query: 809  VTTNSPLPPSLTESSTEQTLPATSTNLAQMSPTFTTTILKTSQPLMTTPGTLSSTASLVT 868
                + +P     +         S+ L+   P   +T + T+Q   T     +S   L  
Sbjct: 4640 SFDATFIPTPAQSTKFPDIFSVASSRLSNSPPMTISTHMTTTQ---TGSSGATSKIPLAL 4696

Query: 869  GPIAVQTTAGKQLSLTHPEILVPQISTEG----GISTERNRVIVDATTGLIPL----TSV 920
                ++T+AG            P + TEG     I+T  N  + D +    P     +S 
Sbjct: 4697 DTSTLETSAG-----------TPSVVTEGFAHSKITTAMNNDVKDVSQTNPPFQDEASSP 4745

Query: 921  PTSAKEMTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSATF--AVQSSTQSPT 978
             + A  + T L  +  ++P   S  +  S  + + S+    A K  T    V SS QS +
Sbjct: 4746 SSQAPVLVTTLPSSVAFTPQWHSTSSPVSMSSVLTSSLVKTAGKVDTSLETVTSSPQSMS 4805

Query: 979  TVSSSASVNSCA 990
                  SV S A
Sbjct: 4806 NTLDDISVTSAA 4817



 Score = 72.8 bits (177), Expect = 2e-12
 Identities = 234/1059 (22%), Positives = 381/1059 (35%), Gaps = 193/1059 (18%)

Query: 67   TPPRERRGPATP---GPSYRAPEPGAAT--QRGPSGRAPRGG--------SADAAWKHWP 113
            TPP E     +     P+  +P P ++T  Q  PS   P           + D      P
Sbjct: 5326 TPPVEETSSVSSLMSSPAMTSPSPVSSTSPQSIPSSPLPVTALPTSVLVTTTDVLGTTSP 5385

Query: 114  ESNTEA--HVENITFYQNQEDFSTVSSKEGVMVQTSGKSHAASDAPENLTLLAETADARG 171
            ES T +  ++ +IT ++    +   +  E  M       H+ + A  N+          G
Sbjct: 5386 ESVTSSPPNLSSIT-HERPATYKDTAHTEAAM------HHSTNTAVTNV----------G 5428

Query: 172  RSGSSSRTNFTILPVGYSLEIATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTA 231
             SGS  ++  ++L    + + AT L S +  L   S+   S+S+    +    QT+  TA
Sbjct: 5429 TSGSGHKSQSSVLADSETSK-ATPLMSTTSTLGDTSV---STSTPNISQTNQIQTEP-TA 5483

Query: 232  SEMGTERAMGLSEEWTVHSQEATTSAWSPSFLPALEMGELTTPSRKRNSSG--------- 282
            S     R    SE+ +  ++  T  ++ P+       G +T  SR   SS          
Sbjct: 5484 SLSPRLRESSTSEKTSSTTETNTAFSYVPT-------GAITQASRTEISSSRTSISDLDR 5536

Query: 283  ----PDLSWLHFYRTAASSPLL----DLSSSSESTEKLNNSTGLQSSSVSQTKTMH---- 330
                PD+S     R   +SP++    +++ ++++T     S G+     S T        
Sbjct: 5537 PTIAPDISTGMITRLF-TSPIMTKSAEMTVTTQTTTPGATSQGILPWDTSTTLFQGGTHS 5595

Query: 331  -VATVFTDGGPRTLRSLTVSLGPVSKTEGFPKDSRIATTSSSVLLSPSAVESRRNSRVTG 389
             V+  F      TLRS T        T    + S   +  S  + SPS V S     +  
Sbjct: 5596 TVSQGFPHSEITTLRSRTPGDVSWMTTPPVEETSSGFSLMSPSMTSPSPVSSTSPESIPS 5655

Query: 390  NPGDEEFIEPS----TENEFGLTSLRWQNDSPTFGEHQLASSSEVQNGSPMSQTETVSRS 445
            +P     +  S    T N  G TS             +  +SS     SP  +  T  + 
Sbjct: 5656 SPLPVTALLTSVLVTTTNVLGTTS------------PEPVTSSPPNLSSPTQERLTTYKD 5703

Query: 446  VAPMRGGEITAHWLLTNSTTSADVTGSSASYPEGVNASVLTQFSDSTVQSGGSHTALGDR 505
             A       + H     + T+    G+S S  E  ++      +       G   A+GD 
Sbjct: 5704 TAHTEAMHASMH-----TNTAVANVGTSISGHESQSSVPADSHTSKATSPMGITFAMGDT 5758

Query: 506  SYSESS-----STSSSESLNSSAPRGERSIAGISYGQVRGTAIEQRTSSDHTDHTYLSST 560
            S S S+     +   +ES +S  P             +R T   +  ++     T LS  
Sbjct: 5759 SVSTSTPAFFETRIQTESTSSLIPG------------LRDTRTSEEINTVTETSTVLSEV 5806

Query: 561  FTKGERALLSITDNSSSSDIVESSTSYIKISNSSHSEYSSFFHAQT-------------E 607
             T       + T   S ++++ SS +   IS   HS+ S +   +T              
Sbjct: 5807 PT-------TTTTEVSRTEVITSSRT--TISGPDHSKMSPYISTETITRLSTFPFVTGST 5857

Query: 608  RSNISSYDGEYAQPSTESPVLHTSNLPSYTPTIN-----MPNTSVVLDTDAEFVSDSSSS 662
               I++  G     S  +  L TS+  S+  T +      P++             S  S
Sbjct: 5858 EMAITNQTGPIGTISQATLTLDTSSTASWEGTHSPVTQRFPHSEETTTMSRSTKGVSWQS 5917

Query: 663  SSSSSSSSSSGPPLPLPSVSQSHHLFSSILPSTRAS----VHLLKSTSDASTPWSSSPSP 718
              S   +SS   P+PLP+++    L+S++  S+  S      LL S    +     + S 
Sbjct: 5918 PPSVEETSSPSSPVPLPAITSHSSLYSAVSGSSPTSALPVTSLLTSGRRKTIDMLDTHSE 5977

Query: 719  LPVSLTTSTSAPLSVSQTTLPQSSSTPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADL 778
            L  S   S S+  S    T   S++T  +  +  T  T+  T   T+ M  LHSS    +
Sbjct: 5978 LVTSSLPSASS-FSGEILTSEASTNTETIHFSENTAETNMGT---TNSMHKLHSS--VSI 6031

Query: 779  KSQSTPHQEKVITES-KSPSLVSLPT---ESTKAV--TTNSPLPPSLTESSTEQTLPATS 832
             SQ + H    +T S    ++VS  T     TK V   + SPL P L E ST   + +T+
Sbjct: 6032 HSQPSGHTPPKVTGSMMEDAIVSTSTPGSPETKNVDRDSTSPLTPELKEDSTALVMNSTT 6091

Query: 833  TNLAQMSPTFTTTILKTSQPLMT------TPGTLSSTASLVTGP---------------- 870
             +    S        + S+  +T       P +  ST S    P                
Sbjct: 6092 ESNTVFSSVSLDAATEVSRAEVTYYDPTFMPASAQSTKSPDISPEASSSHSNSPPLTIST 6151

Query: 871  ---IAVQTTAGKQLSLTHPEILVPQISTEGGISTERNRVIVDATTGLI-------PLTSV 920
               IA QT      SL    +    I+T  G  + R +  VD+ T  +        L + 
Sbjct: 6152 HKTIATQTGPSGVTSLGQLTLDTSTIATSAGTPSARTQDFVDSETTSVMNNDLNDVLKTS 6211

Query: 921  PTSAKEMTT-----KLGVTAEYSPASRSL---GTSPSPQTTVVSTAEDLAPKSATFAVQS 972
            P SA+E  +      L VT   SP + +L    TS     T V T            ++ 
Sbjct: 6212 PFSAEEANSLSSQAPLLVTTSPSPVTSTLQEHSTSSLVSVTSVPTPTLAKITDMDTNLEP 6271

Query: 973  STQSP-----TTVSSSASVNSCAVNPCLHNGECVADNTS 1006
             T+SP     T  +S A+ ++  ++P ++        TS
Sbjct: 6272 VTRSPQNLRNTLATSEATTDTHTMHPSINTAVANVGTTS 6310



 Score = 71.6 bits (174), Expect = 5e-12
 Identities = 196/947 (20%), Positives = 352/947 (37%), Gaps = 154/947 (16%)

Query: 158  ENLTLLAETADARGRSGSSSRTNFTILPVGYSLEIATALTSQSGNLASESLHLPSSSSEF 217
            E +  + ET+       +++ T  +   V     I ++ T+ SG     S   P  S+E 
Sbjct: 5791 EEINTVTETSTVLSEVPTTTTTEVSRTEV-----ITSSRTTISG--PDHSKMSPYISTET 5843

Query: 218  DERIAAFQTKSGTASEMGTERA--MGLSEEWTVHSQEATTSAWSPSFLPALEMGELTTPS 275
              R++ F   +G+     T +   +G   + T+    ++T++W  +  P  +    +  +
Sbjct: 5844 ITRLSTFPFVTGSTEMAITNQTGPIGTISQATLTLDTSSTASWEGTHSPVTQRFPHSEET 5903

Query: 276  RKRNSSGPDLSWLHFYRTAASSPLLDLSSSSESTEKLNNSTGLQS-----SSVSQTKTMH 330
               + S   +SW        S P ++ +SS  S   L   T   S     S  S T  + 
Sbjct: 5904 TTMSRSTKGVSW-------QSPPSVEETSSPSSPVPLPAITSHSSLYSAVSGSSPTSALP 5956

Query: 331  VATVFTDGGPRTLRSL-------TVSLGPVSKTEGFPKDSRIATTSSSVLLSPSAVESRR 383
            V ++ T G  +T+  L       T SL   S   G    S  +T + ++  S +  E+  
Sbjct: 5957 VTSLLTSGRRKTIDMLDTHSELVTSSLPSASSFSGEILTSEASTNTETIHFSENTAETNM 6016

Query: 384  NS-----------------------RVTGNPGDEEFIEPSTENEFGLTSLRWQNDSPTFG 420
             +                       +VTG+  ++  +  ST       ++   + SP   
Sbjct: 6017 GTTNSMHKLHSSVSIHSQPSGHTPPKVTGSMMEDAIVSTSTPGSPETKNVDRDSTSPLTP 6076

Query: 421  EHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADVTGSSASYPEGV 480
            E +  S++ V N +  +++ TV  SV+     E++   +     T    +  S   P+ +
Sbjct: 6077 ELKEDSTALVMNST--TESNTVFSSVSLDAATEVSRAEVTYYDPTFMPASAQSTKSPD-I 6133

Query: 481  NASVLTQFSDSTVQSGGSHTALGDRSYSESSSTSSSESLNSSAPRGERSIAGISYGQVRG 540
            +    +  S+S   +  +H  +  ++     ++    +L++S      + AG    + + 
Sbjct: 6134 SPEASSSHSNSPPLTISTHKTIATQTGPSGVTSLGQLTLDTSTIA---TSAGTPSARTQD 6190

Query: 541  TAIEQRTSSDHTD--HTYLSSTFTKGERALLSITDNSSSSDIVESSTSYIKISNSSHSEY 598
                + TS  + D      +S F+  E   LS    S +  +V +S S +  +   HS  
Sbjct: 6191 FVDSETTSVMNNDLNDVLKTSPFSAEEANSLS----SQAPLLVTTSPSPVTSTLQEHSTS 6246

Query: 599  S--SFFHAQTER-SNISSYDGEYAQPSTESP-----VLHTSNLPSYTPTINMP-NTSVV- 648
            S  S     T   + I+  D    +P T SP      L TS   + T T++   NT+V  
Sbjct: 6247 SLVSVTSVPTPTLAKITDMDTNL-EPVTRSPQNLRNTLATSEATTDTHTMHPSINTAVAN 6305

Query: 649  ---LDTDAEFV------SDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSILPSTRASV 699
                 +  EF       SD   ++S+   +S+SG  +   S+ +S  +      +T + +
Sbjct: 6306 VGTTSSPNEFYFTVSPDSDPYKATSAVVITSTSGDSIVSTSMPRSSAMKKIESETTFSLI 6365

Query: 700  HLLKSTSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQSSSTPVLPRARET--PVTS 757
              L+ TS +    SSS +   V     T+A   VS+T L  SS T +    + T  P TS
Sbjct: 6366 FRLRETSTSQKIGSSSDTST-VFDKAFTAATTEVSRTELTSSSRTSIQGTEKPTMSPDTS 6424

Query: 758  FQTSTMTSFMTMLHSSQTADLKSQSTPHQE------------------------------ 787
             ++ TM S    L  S+   + +Q+ PH+                               
Sbjct: 6425 TRSVTMLSTFAGLTKSEERTIATQTGPHRATSQGTLTWDTSITTSQAGTHSAMTHGFSQL 6484

Query: 788  -------------------KVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESSTEQTL 828
                                V   S S SL+SLP     A+T+ SP+P +L ES     +
Sbjct: 6485 DLSTLTSRVPEYISGTSPPSVEKTSSSSSLLSLP-----AITSPSPVPTTLPESRPSSPV 6539

Query: 829  PATS---------TNLAQMSPTFTTTILKTSQPLMTTPGTLSSTASLVTGPIAVQTTAGK 879
              TS         T++     +    +  TS  + TT   +  T  +        T  G 
Sbjct: 6540 HLTSLPTSGLVKTTDMLASVASLPPNLGSTSHKIPTTSEDIKDTEKMYPSTNIAVTNVGT 6599

Query: 880  QLSLTHPEILVPQISTEGGISTERNRVIVDATTGLIPLTSVPTSAKEMTTKLGVTAEYSP 939
              S       VP  S    +++    V        I  TS+P S++   T++ + + +S 
Sbjct: 6600 TTSEKESYSSVPAYSEPPKVTSP--MVTSFNIRDTIVSTSMPGSSE--ITRIEMESTFSL 6655

Query: 940  ASRSLGTSPSPQTTVVSTAEDLAPKSATFAVQSSTQSPTTVSSSASV 986
            A    GTS S Q  +VST +       T     ++++    S   S+
Sbjct: 6656 AHGLKGTSTS-QDPIVSTEKSAVLHKLTTGATETSRTEVASSRRTSI 6701



 Score = 71.2 bits (173), Expect = 6e-12
 Identities = 206/891 (23%), Positives = 338/891 (37%), Gaps = 172/891 (19%)

Query: 125  TFYQNQEDFSTVSSKEGVMVQTSGKSHAASDAPENLTLLAETADARGRSGSSSRTNFTIL 184
            T  Q+ +    VSS E V VQT    +  S A  + +   E + + G S SS  ++ ++ 
Sbjct: 1979 TIEQSTQPLHAVSS-EKVSVQTQSTPYVNSVAV-SASPTHENSVSSGSSTSSPYSSASLE 2036

Query: 185  PVGYSLEIATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTASEMGTERAMGLSE 244
             +  ++    A+TS   +L +    LP                  T +   T  +  LS 
Sbjct: 2037 SLDSTISRRNAITSWLWDLTTS---LP------------------TTTWPSTSLSEALSS 2075

Query: 245  EWTVHSQEATTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASSPLLDLSS 304
              +  S  ++T+   P F  A      T+ +++RN   P+        TAAS+   D SS
Sbjct: 2076 GHSGVSNPSSTTTEFPLFSAAS-----TSAAKQRN---PETETHGPQNTAASTLNTDASS 2127

Query: 305  SSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLT-VSLGPVSKTEGFPKDS 363
             +  +E     T + +S  S+       T  +D    T  S    SLG  S   G     
Sbjct: 2128 VTGLSE-----TPVGASISSEVPLPMAITSRSDVSGLTSESTANPSLGTASSA-GTKLTR 2181

Query: 364  RIATTSSSVLLS------PSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQN-DS 416
             I+  +S  L+S      P  V     S  T N   E  I  ++    GL+++     D+
Sbjct: 2182 TISLPTSESLVSFRMNKDPWTVSIPLGSHPTTNT--ETSIPVNSAGPPGLSTVASDVIDT 2239

Query: 417  PTFGEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADVTGSSASY 476
            P+ G    A S    + SP   TE  + S  P    E T H   T S+ + ++T      
Sbjct: 2240 PSDG----AESIPTVSFSPSPDTEVTTISHFP----EKTTHSFRTISSLTHELTSRVTPI 2291

Query: 477  PEGVNASVLTQFSDSTVQSGGSHT-ALGDRSYSESSSTSSSESLNSSAPRGERSIAGISY 535
            P    +S +     ST  +G S +  LG+R            ++ S+AP     +   S+
Sbjct: 2292 PGDWMSSAM-----STKPTGASPSITLGER-----------RTITSAAPTTSPIVLTASF 2335

Query: 536  GQVRGTAIEQRTSSDHTDHTYLSSTFTKGERALLSITDNSSSSDIVESSTSYIKISNSSH 595
             +    +++  T       T  +S      +     +D+SSSSD++ +S     I++S+ 
Sbjct: 2336 TETSTVSLDNET-------TVKTSDILDARKTNELPSDSSSSSDLINTS-----IASSTM 2383

Query: 596  SEYSSFFHAQTERSNISSYDGEYAQPSTESPVLHTSNLPSYTPTINMPNTSVVLDTDAEF 655
                +   + T  S +++         + SP L +S+ P    +    NT       A  
Sbjct: 2384 DVTKTASISPTSISGMTA---------SSSPSLFSSDRPQVPTSTTETNT-------ATS 2427

Query: 656  VSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSILPSTRASVHLLKSTSDASTPWSSS 715
             S SS++ S    S+  G P  LP  + +H +                 TS A   WS  
Sbjct: 2428 PSVSSNTYSLDGGSNVGGTPSTLPPFTITHPV----------------ETSSALLAWSRP 2471

Query: 716  PSPLPVSLTTSTSA---PLSVSQ--TTLPQSSSTPVLPRARETPVTSF-QTSTMTSFMTM 769
                   ++T T++   P S +   T++P   +   +    + P   F +TS      ++
Sbjct: 2472 VRTFSTMVSTDTASGENPTSSNSVVTSVPAPGTWTSVGSTTDLPAMGFLKTSPAGEAHSL 2531

Query: 770  LHSSQTADLKSQSTPH-QEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESSTEQTL 828
            L S  T +  +  TPH    V+T S + S  SL T S      +SP  P+   S      
Sbjct: 2532 LAS--TIEPATAFTPHLSAAVVTGSSATSEASLLTTSESKAIHSSPQTPTTPTSGANWET 2589

Query: 829  PATSTNLAQMSPTFTTTILKTSQPLMTTPGTLSSTASLVTGPIAVQTTAGKQLSLTHPEI 888
             AT  +L  ++ T  TT+   +  ++ T   L ST S                    P  
Sbjct: 2590 SATPESLLVVTETSDTTL---TSKILVTDTILFSTVST-------------------PPS 2627

Query: 889  LVPQISTEGGISTERNRVIVDATTGLIPLT-SVPTSAKEMTTKLGVTAEYSP----ASRS 943
              P   T  G S             L+P T ++P +A E T+ L  + + +P    AS S
Sbjct: 2628 KFPSTGTLSGASFPT----------LLPDTPAIPLTATEPTSSLATSFDSTPLVTIASDS 2677

Query: 944  LGTSPSPQTTV--VSTAEDLAPKSAT--------FAVQSSTQSPTTVSSSA 984
            LGT P    T+   S  + L  K+ +          +Q  T+SP   SS++
Sbjct: 2678 LGTVPETTLTMSETSNGDALVLKTVSNPDRSIPGITIQGVTESPLHPSSTS 2728



 Score = 71.2 bits (173), Expect = 6e-12
 Identities = 205/919 (22%), Positives = 338/919 (36%), Gaps = 151/919 (16%)

Query: 184   LPVGYSLEIATALTSQSGNLASESLHLPSS--SSEFDERIAAFQTKSGTASEMGTERAMG 241
             L      E +TAL   + ++ +      +S  S    ER    QT   ++SE  T     
Sbjct: 10541 LATSLGAETSTALPRTTPSVFNRESETTASLVSRSGAERSPVIQTLDVSSSEPDT----- 10595

Query: 242   LSEEWTVHSQEA--TTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSW-----LHFYRTA 294
              +  W +H  E   T S  +P+F  +    EL T S    S G D+S      +      
Sbjct: 10596 -TASWVIHPAETIPTVSKTTPNFFHS----ELDTVSSTATSHGADVSSAIPTNISPSELD 10650

Query: 295   ASSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVS 354
             A +PL+ +S +  ST     +     +    T   H A   +   PRT+ + +       
Sbjct: 10651 ALTPLVTISGTDTSTTFPTLTKSPHETETRTTWLTHPAET-SSTIPRTIPNFS------- 10702

Query: 355   KTEGFPKDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFI-----EPSTENEFGLTS 409
                        +  + S+  SP A  S     +T +PG E+ +        T+    + +
Sbjct: 10703 --------HHESDATPSIATSPGAETSSAIPIMTVSPGAEDLVTSQVTSSGTDRNMTIPT 10754

Query: 410   LRWQNDSP-------TFGEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTN 462
             L      P       T  E Q +S+      SP + +  V+  V  +     T +  LTN
Sbjct: 10755 LTLSPGEPKTIASLVTHPEAQTSSAIPTSTISP-AVSRLVTSMVTSLAAKTSTTNRALTN 10813

Query: 463   STTSADVTGSSASYPEGVNASV-------LTQFSDSTVQSGGSHTALGDRSYSESSSTSS 515
             S      T S  ++P   + +V           SD+T     SH A       ESSS   
Sbjct: 10814 SPGEPATTVSLVTHPAQTSPTVPWTTSIFFHSKSDTTPSMTTSHGA-------ESSSAVP 10866

Query: 516   SESLNSSAPRGERSIAGISYGQVRGTAIEQRTSSDHTDHTYLSSTFTKGERALLSITDNS 575
             + ++++  P G  +    S   V  T I   T S     T  S   + GE A  +I   +
Sbjct: 10867 TPTVSTEVP-GVVTPLVTSSRAVISTTIPILTLSPGEPETTPSMATSHGEEASSAIPTPT 10925

Query: 576   SSSDIVESSTSYIKISNSSHSEYS-----SFFHAQTERSNISSYDGEY--AQPST--ESP 626
              S  +    TS +  S +  S        S    +T  S  +S+  E   A P+   E P
Sbjct: 10926 VSPGVPGVVTSLVTSSRAVTSTTIPILTFSLGEPETTPSMATSHGTEAGSAVPTVLPEVP 10985

Query: 627   VLHTS-----------NLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPP 675
              + TS            LP+ T +   P T+  + T     S  + +SS+  + S   P 
Sbjct: 10986 GMVTSLVASSRAVTSTTLPTLTLSPGEPETTPSMAT-----SHGAEASSTVPTVSPEVPG 11040

Query: 676   LPLPSVSQSHHLFSSILPS------------TRASVHLLKSTSDASTPW-----SSSPSP 718
             +    V+ S  + S+ +P+            + A+ H  +++S   TP      S   +P
Sbjct: 11041 VVTSLVTSSSGVNSTSIPTLILSPGELETTPSMATSHGAEASSAVPTPTVSPGVSGVVTP 11100

Query: 719   LPVSL--TTSTSAPLSVSQTTLPQS-----------SSTPVLPRARETP------VTSFQ 759
             L  S    TST+ P+    ++ P++           +S+ VL  + E P      VTS +
Sbjct: 11101 LVTSSRAVTSTTIPILTLSSSEPETTPSMATSHGVEASSAVLTVSPEVPGMVTSLVTSSR 11160

Query: 760   TSTMTSFMTMLHSSQTADLKSQSTPHQE-KVITESKSPSLVSLPTES---TKAVTTNSPL 815
               T T+  T+  SS   +  +    H E K+I  S  P+L   PT     T  VT++   
Sbjct: 11161 AVTSTTIPTLTISSDEPETTTSLVTHSEAKMI--SAIPTLAVSPTVQGLVTSLVTSSGSE 11218

Query: 816   PPSLTESSTEQTLPATSTNLAQMSPTFTTTILKTSQPLMTTPGTLSSTASLVTGPIAVQT 875
               + +  +   + P T  +      T  ++++ T   L  + G   +  SLVT P    +
Sbjct: 11219 TSAFSNLTVASSQPETIDSWVAHPGTEASSVVPT---LTVSTGEPFTNISLVTHPAESSS 11275

Query: 876   TAGKQLS-LTHPE-------ILVPQISTEGGISTERNRVIVDATTGLIPLTSVPTSAKEM 927
             T  +  S  +H E       +  P+  +   IST  +  I    T L+  +    SA   
Sbjct: 11276 TLPRTTSRFSHSELDTMPSTVTSPEAESSSAISTTISPGIPGVLTSLVTSSGRDISATFP 11335

Query: 928   TTKLGVTAEYSPASRSLGTSPSPQTTVV--------STAEDLAPKSATFAVQSSTQSPTT 979
             T  +  +   S A+ S  T P+  +T V         +  D  P  AT     +T    T
Sbjct: 11336 T--VPESPHESEATASWVTHPAVTSTTVPRTTPNYSHSEPDTTPSIATSPGAEATSDFPT 11393

Query: 980   VSSSASVNSCAVNPCLHNG 998
             ++ S  V     +    +G
Sbjct: 11394 ITVSPDVPDMVTSQVTSSG 11412



 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 168/816 (20%), Positives = 309/816 (37%), Gaps = 98/816 (12%)

Query: 226   TKSGTASEMGTERAMGLSEEWTVHSQEATTSAWSPSFLPALEMGELTTPSRKRNSSGPDL 285
             T + T S  G+   +  S+     S + ++  W P+        ++ TP     S     
Sbjct: 10182 TPTNTPSSPGSTHLLQSSKTDFTSSAKTSSPDWPPASQYTEIPVDIITPFNASPSITEST 10241

Query: 286   SWLHFYRTAASSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRS 345
                 F  +  +  + + S+   ST+ L ++  + + +V  + +  + +  T G PR +  
Sbjct: 10242 GITSFPESRFTMSVTE-STHHLSTDLLPSAETISTGTVMPSLSEAMTSFATTGVPRAISG 10300

Query: 346   LTVSLGPVSKTEGFPKDSRIATTSSSVLLSPSAVESRRNSRVTGN---PGDEEFIEPSTE 402
                S  P S+TE  P D+ ++T + S+  S     S      T +   P   E I  S+ 
Sbjct: 10301 ---SGSPFSRTESGPGDATLSTIAESLPSSTPVPFSSSTFTTTDSSTIPALHE-ITSSSA 10356

Query: 403   NEFGLTSLRWQNDSPTFGEHQLASSSEV--QNGSPMSQTETVSRSVAPMRGGEITAHWLL 460
               + + +      S T G   + S+ +   Q G   S     +R    +  G +T+ + +
Sbjct: 10357 TPYRVDTSLGTESSTTEGRLVMVSTLDTSSQPGRTSSSPILDTRMTESVELGTVTSAYQV 10416

Query: 461   TNSTTSADVTG----------SSASYPEGVNASVLTQFSDSTVQSGGSHTALGDRSYSES 510
              + +T    T           + A++   +      Q S S     G HT  G     E+
Sbjct: 10417 PSLSTRLTRTDGIMEHITKIPNEAAHRGTIRPVKGPQTSTSPASPKGLHT--GGTKRMET 10474

Query: 511   SSTSSSESLNSSAPRGERSIAGISYGQVRGTAIEQRTSSD--HTDHTYLSSTFTKGERAL 568
             ++T+   +  +       ++    Y    GT      S     T  T +  T       +
Sbjct: 10475 TTTALKTTTTALKTTSRATLTTSVYTPTLGTLTPLNASMQMASTIPTEMMITTPYVFPDV 10534

Query: 569   LSITDNSSSSDIVESSTSYIKISNSSHSEYSSFFHAQTERSN------ISSYDGEYAQP- 621
                T + ++S   E+ST+  + + S  +  S    +   RS       I + D   ++P 
Sbjct: 10535 PETTSSLATSLGAETSTALPRTTPSVFNRESETTASLVSRSGAERSPVIQTLDVSSSEPD 10594

Query: 622   STESPVLHTSN----LPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLP 677
             +T S V+H +     +   TP         V  T     +D SS+  ++ S S      P
Sbjct: 10595 TTASWVIHPAETIPTVSKTTPNFFHSELDTVSSTATSHGADVSSAIPTNISPSELDALTP 10654

Query: 678   LPSVSQSHHLFSSILPSTRASVHLLKSTSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTT 737
             L ++S +    S+  P+   S H     ++  T W + P+       TS++ P ++   +
Sbjct: 10655 LVTISGTDT--STTFPTLTKSPH----ETETRTTWLTHPAE------TSSTIPRTIPNFS 10702

Query: 738   LPQSSSTPVLPRARETPVTSFQTSTMTSFMTMLHSSQ---TADLKSQSTPHQEKVITESK 794
               +S +TP +  +        +TS+    MT+   ++   T+ + S  T     + T + 
Sbjct: 10703 HHESDATPSIATS-----PGAETSSAIPIMTVSPGAEDLVTSQVTSSGTDRNMTIPTLTL 10757

Query: 795   SP-------SLVSLPTESTKAVTTNSPLPPSLTESSTEQTLPATSTNLAQMSPTFTTTIL 847
             SP       SLV+ P   T +    S + P+++   T        T+LA  + T      
Sbjct: 10758 SPGEPKTIASLVTHPEAQTSSAIPTSTISPAVSRLVTSMV-----TSLAAKTST------ 10806

Query: 848   KTSQPLMTTPGTLSSTASLVTGPIAVQTTAGKQLSL--THPEILVPQISTEGGISTERNR 905
              T++ L  +PG  ++T SLVT P     T     S+         P ++T  G       
Sbjct: 10807 -TNRALTNSPGEPATTVSLVTHPAQTSPTVPWTTSIFFHSKSDTTPSMTTSHGAE----- 10860

Query: 906   VIVDATTGLIPLTSVPTSAKEMTTKLGVTAEYSPASRS---LGTSPSPQTTVVSTAEDLA 962
                  ++  +P  +V T    + T L VT+  +  S +   L  SP    T  S A    
Sbjct: 10861 -----SSSAVPTPTVSTEVPGVVTPL-VTSSRAVISTTIPILTLSPGEPETTPSMATSHG 10914

Query: 963   PKSATFAVQSSTQSP-------TTVSSSASVNSCAV 991
              + A+ A+ + T SP       + V+SS +V S  +
Sbjct: 10915 -EEASSAIPTPTVSPGVPGVVTSLVTSSRAVTSTTI 10949



 Score = 68.2 bits (165), Expect = 5e-11
 Identities = 207/938 (22%), Positives = 372/938 (39%), Gaps = 177/938 (18%)

Query: 163  LAETADARGRSGSSSRTNFTILPVGYSLEIATAL----TSQSGNLASESLHLPSSS--SE 216
            ++ T  A   S S+S T+        + E+  A     TS   +L+S S+ + ++S  + 
Sbjct: 7407 VSSTLPASSHSSSASVTSLLTPGQVKTTEVLDASAEPETSSPPSLSSTSVEILATSEVTT 7466

Query: 217  FDERIAAFQ----TKSGTASEMGTERAMGLSEEWTVHSQEATTSAWSPSFLPALEMGELT 272
              E+I  F     TK GT+S      +  L +  T    +AT++  + S +    +  LT
Sbjct: 7467 DTEKIHPFSNTAVTKVGTSSSGHESPSSVLPDSETT---KATSAMGTISIMGDTSVSTLT 7523

Query: 273  TP--SRKRNSSGPDLSWLHFYRTAASSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMH 330
                + ++  S P  S     R  ++S   + S ++E+   L+  +   ++ VS+T+ + 
Sbjct: 7524 PALSNTRKIQSEPASSLTTRLRETSTSE--ETSLATEANTVLSKVSTGATTEVSRTEAIS 7581

Query: 331  VATVFTDGGPRTLRSLTVSLGPVSKTEGFPKDSRIATTSSSVLL------SPSAVESRRN 384
             +     G  ++  S  +S+G + +       S + T S+ + +      S S +ES  N
Sbjct: 7582 FSRTSMSGPEQSTMSQDISIGTIPRISA----SSVLTESAKMTITTQTGPSESTLESTLN 7637

Query: 385  SRVTGNPGDEE--------FIEPSTENEFGLTSLRWQNDSPTFGEHQLASSSEVQNGSPM 436
                  P   E        F  P      G         SP F +     SS +   +  
Sbjct: 7638 LNTATTPSWVETHSIVIQGFPHPEMTTSMGRGPGGVSWPSPPFVKETSPPSSPLSLPAVT 7697

Query: 437  SQTETVSRSVAPMRGGEITAHWLLTNS-TTSADVTGSSASYPEGVNASV-------LTQF 488
            S     +  +A +    +    LLT+   T+ D+ G+S       ++S+       LT +
Sbjct: 7698 SPHPVSTTFLAHIPPSPLPVTSLLTSGPATTTDILGTSTEPGTSSSSSLSTTSHERLTTY 7757

Query: 489  SDS--------TVQSGGSHTALGDRSY-SESSSTSSSESLNSSAPRGERSIAGISYGQVR 539
             D+        +  +GG++ A     Y S+SS  + S  + +++  G+ S+   +   + 
Sbjct: 7758 KDTAHTEAVHPSTNTGGTNVATTSSGYKSQSSVLADSSPMCTTSTMGDTSVLTSTPAFLE 7817

Query: 540  GTAIEQRTSSDHTDHTYLSSTFTKGERALLSITDNSSSSDIVESSTSYIKISNSSHSEYS 599
               I+          T L+S+ T G R        SS + +   ST   K+   + +E S
Sbjct: 7818 TRRIQ----------TELASSLTPGLRESSGSEGTSSGTKM---STVLSKVPTGATTEIS 7864

Query: 600  SFFHAQTERSNISSYDGEYAQPSTESPVLHTSNLPSY-TPTINMPNTSVVLDTDAEFVSD 658
                    + +++S  G     ST SP + T  +  + T  +   +  + ++T    +  
Sbjct: 7865 --------KEDVTSIPGP--AQSTISPDISTRTVSWFSTSPVMTESAEITMNTHTSPLGA 7914

Query: 659  SSSSSSSSSSSSSSGPPLPLPSVSQ--SHHLFSSI---------------LPSTRASVHL 701
            ++  +S+  +SS++   +   ++SQ  SH   S++               L  TR S  L
Sbjct: 7915 TTQGTSTLDTSSTTSLTMTHSTISQGFSHSQMSTLMRRGPEDVSWMSPPLLEKTRPSFSL 7974

Query: 702  LKSTSDAST-------PWSSSPSPLPV-SLTTS----------------TSAPLSVSQTT 737
            + S +  S        P S S SPLPV SL TS                T++P ++S T+
Sbjct: 7975 MSSPATTSPSPVSSTLPESISSSPLPVTSLLTSGLAKTTDMLHKSSEPVTNSPANLSSTS 8034

Query: 738  LPQSSSTPVLPRARET------------------PVTSF-----QTSTMTSFMTMLHSSQ 774
            +   +++ V     +T                    TSF     QTS +TS M +  + +
Sbjct: 8035 VEILATSEVTTDTEKTHPSSNRTVTDVGTSSSGHESTSFVLADSQTSKVTSPMVITSTME 8094

Query: 775  TADLKSQSTP---HQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESSTEQT-LPA 830
               + S STP      ++ TE  S   + L   S+   T+ +      TE ST  + +P 
Sbjct: 8095 DTSV-STSTPGFFETSRIQTEPTSSLTLGLRKTSSSEGTSLA------TEMSTVLSGVPT 8147

Query: 831  TSTNLAQMSPTFTTTILKTS----QPLMTTPGTLSSTAS-LVTGPIAVQTTAGKQLSLTH 885
             +T  A++S T  T+  +TS      L  +P T + T + L T  I  ++      + T 
Sbjct: 8148 GAT--AEVSRTEVTSSSRTSISGFAQLTVSPETSTETITRLPTSSIMTESAEMMIKTQTD 8205

Query: 886  PEILVPQISTEGGISTERNRVIVDATTGLIPLTSVPTSAKEMTTKLGVTAEYSPASRSLG 945
            P    P+ +    IST  N V   +T       +   S  EMTT +         SRS G
Sbjct: 8206 PPGSTPESTHTVDISTTPNWVETHST------VTQRFSHSEMTTLV---------SRSPG 8250

Query: 946  TSPSPQTTVVSTAEDLAPKSATFAVQSSTQSPTTVSSS 983
                P     S+ E+ +  S+  ++ ++T SP+ VSS+
Sbjct: 8251 DMLWPSQ---SSVEETSSASSLLSLPATT-SPSPVSST 8284



 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 191/894 (21%), Positives = 329/894 (36%), Gaps = 102/894 (11%)

Query: 158   ENLTLLAETADARGRSGSSS---RT-----NFTILPVGYSLEIATALTSQSGNLASE--- 206
             E +T  A T   R  SGS S   RT     + T+  +  SL  +T +   S    +    
Sbjct: 10284 EAMTSFATTGVPRAISGSGSPFSRTESGPGDATLSTIAESLPSSTPVPFSSSTFTTTDSS 10343

Query: 207   ---SLHLPSSSSEFDERIAAFQTKSGTASEMGTERAMGLSEEWTVHSQEATTSAWSP--- 260
                +LH  +SSS    R+    T  GT S   TE  + +       SQ   TS+ SP   
Sbjct: 10344 TIPALHEITSSSATPYRV---DTSLGTESST-TEGRLVMVSTLDTSSQPGRTSS-SPILD 10398

Query: 261   -SFLPALEMGELTT----PSRKRNSSGPDLSWLHFYRT-----------------AASSP 298
                  ++E+G +T+    PS     +  D    H  +                   ++SP
Sbjct: 10399 TRMTESVELGTVTSAYQVPSLSTRLTRTDGIMEHITKIPNEAAHRGTIRPVKGPQTSTSP 10458

Query: 299   LLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVSKTEG 358
                    +  T+++  +T    ++ +  KT   AT+ T     TL +LT     +     
Sbjct: 10459 ASPKGLHTGGTKRMETTTTALKTTTTALKTTSRATLTTSVYTPTLGTLTPLNASMQMAST 10518

Query: 359   FPKDSRIAT---------TSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTS 409
              P +  I T         T+SS+  S  A  S    R T +  + E     +E    L S
Sbjct: 10519 IPTEMMITTPYVFPDVPETTSSLATSLGAETSTALPRTTPSVFNRE-----SETTASLVS 10573

Query: 410   LRWQNDSPTFGEHQLASSSEVQNGS----PMSQTETVSRSVAPMRGGEITAHWLLTNSTT 465
                   SP      ++SS      S    P     TVS++       E+       +ST 
Sbjct: 10574 RSGAERSPVIQTLDVSSSEPDTTASWVIHPAETIPTVSKTTPNFFHSELDT----VSSTA 10629

Query: 466   SADVTGSSASYPEGVNASVLTQFSDSTVQSG-GSHTALGDRSYSESSSTSSSESLNSSAP 524
             ++     S++ P  ++ S L   +     SG  + T     + S   + + +  L   A 
Sbjct: 10630 TSHGADVSSAIPTNISPSELDALTPLVTISGTDTSTTFPTLTKSPHETETRTTWLTHPAE 10689

Query: 525   RGE---RSIAGISYGQVRGTAIEQRTSSDHTDHTYLSSTFTKGERALLSITDNSSSSDIV 581
                   R+I   S+ +   T     +    T       T + G   L++    SS +D  
Sbjct: 10690 TSSTIPRTIPNFSHHESDATPSIATSPGAETSSAIPIMTVSPGAEDLVTSQVTSSGTDRN 10749

Query: 582   ESSTSYIKISNSSHSEYSSFFHAQTERSNISSYDGEYAQPSTESPVLHTSNLPSYTPTIN 641
              +  +         +  S   H + + S+           ST SP +  S L +   T  
Sbjct: 10750 MTIPTLTLSPGEPKTIASLVTHPEAQTSSA-------IPTSTISPAV--SRLVTSMVTSL 10800

Query: 642   MPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSILPSTRASVHL 701
                TS           + +++ S  +  + + P +P  + S   H  S   PS   S H 
Sbjct: 10801 AAKTSTTNRALTNSPGEPATTVSLVTHPAQTSPTVPW-TTSIFFHSKSDTTPSMTTS-HG 10858

Query: 702   LKSTSDASTPWSSSPSPLPVS-LTTSTSAPLSVSQTTLPQSSSTPVLPRARETPVTSFQT 760
              +S+S   TP  S+  P  V+ L TS+ A +S   TT+P  + +P  P    +  TS   
Sbjct: 10859 AESSSAVPTPTVSTEVPGVVTPLVTSSRAVIS---TTIPILTLSPGEPETTPSMATSHGE 10915

Query: 761   STMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLV-SL-PTESTKAVTTNSPLPPS 818
                ++  T   S     + + S     + +T +  P L  SL   E+T ++ T+      
Sbjct: 10916 EASSAIPTPTVSPGVPGVVT-SLVTSSRAVTSTTIPILTFSLGEPETTPSMATSHGTEAG 10974

Query: 819   LTESSTEQTLPATSTNLAQMSPTFTTTILKTSQPLMTTPGTLSSTASLVTGPIAVQTTAG 878
                 +    +P   T+L   S   T+T L T   L  +PG   +T S+ T   A  ++  
Sbjct: 10975 SAVPTVLPEVPGMVTSLVASSRAVTSTTLPT---LTLSPGEPETTPSMATSHGAEASSTV 11031

Query: 879   KQLSLTHPEILVPQISTEGGISTERNRVIVDATTGLIPLTSVPTS--------AKEMTTK 930
               +S   P ++   +++  G+++     ++ +   L    S+ TS            T  
Sbjct: 11032 PTVSPEVPGVVTSLVTSSSGVNSTSIPTLILSPGELETTPSMATSHGAEASSAVPTPTVS 11091

Query: 931   LGVTAEYSP---ASRSLGTSPSPQTTVVSTAEDLAPKSATFAVQSSTQSPTTVS 981
              GV+   +P   +SR++ ++  P  T+ S+  +  P  AT     ++ +  TVS
Sbjct: 11092 PGVSGVVTPLVTSSRAVTSTTIPILTLSSSEPETTPSMATSHGVEASSAVLTVS 11145



 Score = 66.2 bits (160), Expect = 2e-10
 Identities = 204/973 (20%), Positives = 350/973 (35%), Gaps = 144/973 (14%)

Query: 99   APRGGSADAAWKHWPESNTEAHVENITFYQNQEDFSTVSSKEGVMVQTSGKSH-AASDAP 157
            +P  GSA + W     S+  +    +T       FST      +++ T   S     + P
Sbjct: 1140 SPDPGSARSTWLGILSSSPSSPTPKVTM---SSTFSTQRVTTSMIMDTVETSRWNMPNLP 1196

Query: 158  ENLTLLAETADARGRSGSSSRTNFTILPVGYSLEIATALTSQSGNLASESLHLPSSSSEF 217
               +L        G  G S     T++P+  +   AT+L +  G L + S + P S++  
Sbjct: 1197 STTSLTPSNIPTSGAIGKS-----TLVPLD-TPSPATSLEASEGGLPTLSTY-PESTNTP 1249

Query: 218  DERIAAFQTKSGTASEMGTERAMGLSEEWTVHSQEATTSAWSPSFLPALEMGELTTPSRK 277
               + A  +    ++   T  ++                +++P   P++E     + +R 
Sbjct: 1250 SIHLGAHASSESPSTIKLTMASV------------VKPGSYTPLTFPSIETHIHVSTARM 1297

Query: 278  RNSSGPDLSWLHFYRTAASSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVF-- 335
              SSG             SSP +     + +    + +T + ++    T +  V+T    
Sbjct: 1298 AYSSG-------------SSPEMTAPGETNTGSTWDPTTYITTTDPKDTSSAQVSTPHSV 1344

Query: 336  -----TDGGPRTLRSLTVSLGPVSKTEGFPKDSRIATTS---------SSVLLSPSAVES 381
                 T+  P+T  +   +     K    P  +  AT +         S+ L      E 
Sbjct: 1345 RTLRTTENHPKTESATPAAYSGSPKISSSPNLTSPATKAWTITDTTEHSTQLHYTKLAEK 1404

Query: 382  RRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQNDSPTFGEHQLASSSEVQNGSPMSQTET 441
                     PG    + P+               SPT G   L  +S+V  G P+    +
Sbjct: 1405 SSGFETQSAPGPVSVVIPT---------------SPTIGSSTLELTSDVP-GEPLVLAPS 1448

Query: 442  VSRSVA-PMRGGEITAHWL---LTNSTTSADVTGSSASYPEGVNASVLTQFSDSTVQSGG 497
               ++  PM      A WL   LT    S D+  SS S P    A +    S  + +   
Sbjct: 1449 EQTTITLPM------ATWLSTSLTEEMASTDLDISSPSSPMSTFA-IFPPMSTPSHELSK 1501

Query: 498  SHTALGDRSYSESSSTSSSESLNSSAPRGERSIAGISYGQVRGTA-IEQRTSSDHTDHTY 556
            S         ++S++      + S    G+ +   I+      T+ IE  T +  T    
Sbjct: 1502 SEADTSAIRNTDSTTLDQHLGIRSLGRTGDLTTVPITPLTTTWTSVIEHSTQAQDTLSAT 1561

Query: 557  LSSTF-TKGERALLSITDNSSSSDIVESSTSYIKISNSSHSEYSSFFHAQTERSNISSYD 615
            +S T  T+  +   SI  ++S S + E     +     S SE ++F+   T+  +     
Sbjct: 1562 MSPTHVTQSLKDQTSIPASASPSHLTEVYPE-LGTQGRSSSEATTFWKPSTDTLSREIET 1620

Query: 616  GEYAQPSTESPVLHTSNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPP 675
            G     ST      T+   S   T+ + +  +   + AE  ++ +    SS+++ S    
Sbjct: 1621 GPTNIQSTPPMDNTTTGSSSSGVTLGIAHLPIGTSSPAETSTNMALERRSSTATVSMAGT 1680

Query: 676  LPLPSVSQSHHLFSSILPSTRASVHLLKSTSDASTPWSSSPSP-LPVSLTTSTSAPLSVS 734
            + L   S      S  L   R S  L +ST++  T  S   SP L     T+ S+ L  S
Sbjct: 1681 MGLLVTSAPGRSISQSLG--RVSSVLSESTTEGVTDSSKGSSPRLNTQGNTALSSSLEPS 1738

Query: 735  -------QTTLPQSSSTPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADLKSQSTPHQE 787
                    T++P +SS P  P       ++F T  +T+ M       T+D+   S     
Sbjct: 1739 YAEGSQMSTSIPLTSS-PTTPDVEFIGGSTFWTKEVTTVM-------TSDISKSSAR--- 1787

Query: 788  KVITESKSPSLVSLPTEST------KAVTTNSPLPPSLTESSTEQTLPATSTNLAQMSPT 841
               TES S +L+S    ST      K  T +  LP           +  T +N    +P 
Sbjct: 1788 ---TESSSATLMSTALGSTENTGKEKLRTASMDLPSPTPSMEVTPWISLTLSN----APN 1840

Query: 842  FTTTILKTSQPLMTTPGTLSSTASLVTGPIAV------QTTAGKQLSL---THPEILV-- 890
             T ++  +     ++ GTL++  SL TG            T+ K LS+   TH  +    
Sbjct: 1841 TTDSLDLSHGVHTSSAGTLATDRSLNTGVTRASRLENGSDTSSKSLSMGNSTHTSMTYTE 1900

Query: 891  -----------PQISTEGGISTERNRVIVDATTGLIPLTSVPTSAKEMTTKLGVTAEYSP 939
                       P+ S  G  +T  +     A +  +P +S+P    E     G+T+    
Sbjct: 1901 KSEVSSSIHPRPETSAPGAETTLTSTPGNRAISLTLPFSSIPV---EEVISTGITSGPDI 1957

Query: 940  ASRSLGTSP-SPQTTVVSTAEDLAPKSATFAVQSSTQSPTTVSSSASVNSCAV--NPCLH 996
             S  +  SP +P T V ++   +   +      SS +      S+  VNS AV  +P   
Sbjct: 1958 NSAPMTHSPITPPTIVWTSTGTIEQSTQPLHAVSSEKVSVQTQSTPYVNSVAVSASPTHE 2017

Query: 997  NGECVADNTSRGY 1009
            N      +TS  Y
Sbjct: 2018 NSVSSGSSTSSPY 2030



 Score = 58.9 bits (141), Expect = 3e-08
 Identities = 207/931 (22%), Positives = 345/931 (37%), Gaps = 159/931 (17%)

Query: 144  VQTSGKSHAASDAPENLTLLAETADARGRSGSSSRTNFTILP-------VGYSLEIATA- 195
            V+TS    A S      + +  T  A G + +SS +  T +P       VG + ++    
Sbjct: 2459 VETSSALLAWSRPVRTFSTMVSTDTASGENPTSSNSVVTSVPAPGTWTSVGSTTDLPAMG 2518

Query: 196  --LTSQSGNLASESLHLPSSSSEFDERI-AAFQTKSGTASEMGTERAMGLSEEWTVHSQE 252
               TS +G   S        ++ F   + AA  T S   SE      +  SE   +HS  
Sbjct: 2519 FLKTSPAGEAHSLLASTIEPATAFTPHLSAAVVTGSSATSEASL---LTTSESKAIHSSP 2575

Query: 253  AT-----------TSAWSPSFLPALEMGELT-----------------TPSRKRNSSGPD 284
             T           TSA   S L   E  + T                 TP  K  S+G  
Sbjct: 2576 QTPTTPTSGANWETSATPESLLVVTETSDTTLTSKILVTDTILFSTVSTPPSKFPSTGT- 2634

Query: 285  LSWLHFYRTAASSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLR 344
            LS   F      +P + L+++ E T  L       ++S   T  + +A+      P T  
Sbjct: 2635 LSGASFPTLLPDTPAIPLTAT-EPTSSL-------ATSFDSTPLVTIASDSLGTVPETTL 2686

Query: 345  SLTVSLGP---VSKTEGFPKDSRIATTSSSVL--------LSPSAVESRRNSRVTGN--- 390
            +++ +      V KT   P  S    T   V          SPS + + RN+   G+   
Sbjct: 2687 TMSETSNGDALVLKTVSNPDRSIPGITIQGVTESPLHPSSTSPSKIVAPRNTTYEGSITV 2746

Query: 391  ---------PGDEEFIEPSTENEF-----GLTSLRWQNDSP-TFGEHQLASSSEVQNGSP 435
                      G   F + S  +E          L   +  P T G   +ASS  +++GS 
Sbjct: 2747 ALSTLPAGTTGSLVFSQSSENSETTALVDSSAGLERASVMPLTTGSQGMASSGGIRSGST 2806

Query: 436  MSQ-TETVSRSVAPMRGGEITAHWLLTNSTTSADVTGSSASYPEGVNASVLTQFSDSTVQ 494
             S  T+T S     M  GE+TA     +  T+  +T + ++ P+G+            V+
Sbjct: 2807 HSTGTKTFSSLPLTMNPGEVTA----MSEITTNRLTATQSTAPKGI-----------PVK 2851

Query: 495  SGGSHTALGDRSYSESSSTSSSESLNSSAPRGERSIAGISYGQVRGTAIEQRTSSDHTDH 554
               + + L     + SS + +  SL ++ P         ++G  + T   + +     D 
Sbjct: 2852 PTSAESGLLTPVSASSSPSKAFASLTTAPP---------TWGIPQSTLTFEFSEVPSLD- 2901

Query: 555  TYLSSTFTKGERALLSITDNSSSSDIVESSTSYIKISNSSHSEYSSFFHAQTERSNISSY 614
            T  +S  T G+ +L +I D+       ++ST+   +S S      +     T+  + SS+
Sbjct: 2902 TKSASLPTPGQ-SLNTIPDS-------DASTASSSLSKSPEKNPRARMMTSTKAISASSF 2953

Query: 615  DGEYAQPSTESPVLHTS-NLPSYTPTINMPNTSVVLDTDAEFVSDS------SSSSSSSS 667
                +   TE+P    S ++  + P +    T      D  + S+S      S +SS+ +
Sbjct: 2954 Q---STGFTETPEGSASPSMAGHEPRVPTSGTG-----DPRYASESMSYPDPSKASSAMT 3005

Query: 668  SSSSSGPPLPLPSVSQSHHLFSSILP---STRASVHLLKSTSDASTPWSSSPSPLPVSLT 724
            S+S +     L S  Q+    SS  P   ST      L  T+  S   S    P  ++  
Sbjct: 3006 STSLASKLTTLFSTGQAARSGSSSSPISLSTEKETSFLSPTASTSRKTSLFLGP-SMARQ 3064

Query: 725  TSTSAPLSVSQTTLPQSSSTPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADLKSQSTP 784
             +    L  S  TL   S T  L  ++E P     + T+         +QT       TP
Sbjct: 3065 PNILVHLQTSALTL---SPTSTLNMSQEEPPELTSSQTIAEEEGTTAETQTLTFTPSETP 3121

Query: 785  HQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESSTEQTLPAT---STNLAQMSPT 841
                 ++    P+     +  T A + + P   SL E +T+ TL  T   S+  AQ + T
Sbjct: 3122 TSLLPVSSPTEPTARRKSSPETWASSISVPAKTSLVE-TTDGTLVTTIKMSSQAAQGNST 3180

Query: 842  FTTTILKT-SQPLMTTPGT--LSSTASLVTG-----PIAVQTTAGKQLSLTHPEILVPQI 893
            +     +T S P  T+PG+  +S+T  +++         +++T       T PE  VP  
Sbjct: 3181 WPAPAEETGSSPAGTSPGSPEMSTTLKIMSSKEPSISPEIRSTVRNSPWKT-PETTVPME 3239

Query: 894  STEGGISTERNRVIVDATTGLIPLTSVPTSAKEMTTKLGVTAEYSPASRSLGTSPSPQ-- 951
            +T   ++ +   +     +G   ++ +PT     T       E   A+  +  SPSP   
Sbjct: 3240 TTVEPVTLQSTAL----GSGSTSISHLPTGTTSPTKS---PTENMLATERVSLSPSPPEA 3292

Query: 952  -TTVVSTAEDLAPKSATFAVQSSTQSPTTVS 981
             T + S       +S       S +SPT  S
Sbjct: 3293 WTNLYSGTPGGTRQSLATMSSVSLESPTARS 3323



 Score = 54.7 bits (130), Expect = 6e-07
 Identities = 208/1000 (20%), Positives = 351/1000 (35%), Gaps = 173/1000 (17%)

Query: 163  LAETADARGRSGSSSRTNFTILPVGYSLEIATALTSQSGNLASESLHLPSSSSEFDERIA 222
            +A TA    ++ S +  +   +    +  I+T +T+   N  S +   P       +   
Sbjct: 3509 IAPTAGHLSQTSSPAEVSILDVTTAPTPGISTTITTMGTNSISTTTPNPEVGMSTMDSTP 3568

Query: 223  AFQTKSGTASEMGTERAMGLSEEWTV----------HSQEATTSAWSPSFLPA-LEMGEL 271
            A + ++ +     T  +   S+ WTV           S    ++  + SFL +  E+  +
Sbjct: 3569 ATERRTTSTEHPSTWSSTAASDSWTVTDMTSNLKVARSPGTISTMHTTSFLASSTELDSM 3628

Query: 272  TTPSRKRNSSGPDL------------------SWLHFYRTAASSPLLDLSSSSE------ 307
            +TP  +    G  L                    L    T AS+P+   S          
Sbjct: 3629 STPHGRITVIGTSLVTPSSDASAVKTETSTSERTLSPSDTTASTPISTFSRVQRMSISVP 3688

Query: 308  ---STEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVSKTEGFPKDSR 364
               ST    +ST  +   VS   T H +T  TD        L  SL  +    G    S 
Sbjct: 3689 DILSTSWTPSSTEAEDVPVSMVSTDHASTK-TDPNTPLSTFLFDSLSTLDWDTGRSLSSA 3747

Query: 365  IATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTEN-EFGLTSLRW--------QND 415
             ATTS+     P    + +   +      E  I P+T    F +  +          ++ 
Sbjct: 3748 TATTSA-----PQGATTPQELTL------ETMISPATSQLPFSIGHITSAVTPAAMARSS 3796

Query: 416  SPTFGEHQLASSSEVQNGSPMSQTETVSRSVAPMRGG---EITAHWLLTNS--------- 463
              TF      S    Q  + +  T +      P       ++  H   T           
Sbjct: 3797 GVTFSRPDPTSKKAEQTSTQLPTTTSAHPGQVPRSAATTLDVIPHTAKTPDATFQRQGQT 3856

Query: 464  --TTSADVTGSSASYPEGVNAS------VLTQFSDSTVQSGGSHTA----LGDRSYSESS 511
              TT A  T  S +  E    S      ++   S+ T++   S ++    L     +  S
Sbjct: 3857 ALTTEARATSDSWNEKEKSTPSAPWITEMMNSVSEDTIKEVTSSSSVLRTLNTLDINLES 3916

Query: 512  STSSSESLNSS-----APRG---ERSIAGISYGQVRGTAIEQRTSSDHTDHTYLSSTFTK 563
             T+SS S  SS     AP     ++     S   V  T     TSS+H  H+ + +    
Sbjct: 3917 GTTSSPSWKSSPYERIAPSESTTDKEAIHPSTNTVETTGWV--TSSEHASHSTIPAHSAS 3974

Query: 564  GERALLSITDNSSSSDIVESSTSYIKISNSSHSEYSSFFHAQ------------TERSNI 611
             +     +T ++    IV  ST+    S  + +E +SF   +            T +++I
Sbjct: 3975 SKLTSPVVTTSTREQAIVSMSTTTWPESTRARTEPNSFLTIELRDVSPYMDTSSTTQTSI 4034

Query: 612  SSYDGEYA---QPSTE---SPVLHTSNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSS 665
             S  G  A    P TE   S  + +S L     + + P+ ++   ++   +++S     +
Sbjct: 4035 ISSPGSTAITKGPRTEITSSKRISSSFLAQSMRSSDSPSEAITRLSNFPAMTESGGMILA 4094

Query: 666  SSSSSSSGPPLPLPSV--SQSHHLFSSILPSTRASVHLLKST------SDASTP------ 711
              +S      L  P++  S +     + L +T+   +  K+T       D S P      
Sbjct: 4095 MQTSPPGATSLSAPTLDTSATASWTGTPLATTQRFTYSEKTTLFSKGPEDTSQPSPPSVE 4154

Query: 712  -WSSSPSPLPVSLTTSTSAPLSVSQTTLPQSSSTPVLP--------RARETPVTSFQTST 762
              SSS S +P+  TTS S  L  SQ   P SS+ PV            + T ++      
Sbjct: 4155 ETSSSSSLVPIHATTSPSNILLTSQGHSP-SSTPPVTSVFLSETSGLGKTTDMSRISLEP 4213

Query: 763  MTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTES---------TKAVTTNS 813
             TS    L S+    L +       K I  S   ++ ++   S         TK     S
Sbjct: 4214 GTSLPPNLSSTAGEALSTYEASRDTKAIHHSADTAVTNMEATSSEYSPIPGHTKPSKATS 4273

Query: 814  PLPPS-----LTES-----STEQTLPATSTNLAQMSPTFTTTILKTSQPLMTTPGTLSST 863
            PL  S     +T S     S+E T   T +++ Q     +T+ + +S    +T  T  S+
Sbjct: 4274 PLVTSHIMGDITSSTSVFGSSETTEIETVSSVNQGLQERSTSQVASSATETSTVITHVSS 4333

Query: 864  ASLVTGPIAVQTTAGKQLSLTHPEILVPQISTEGGISTERNRVIVDATTGLIPLTSVPTS 923
                T     Q T     S++ P   +   +T   +ST       + +T LI   S   S
Sbjct: 4334 GDATTHVTKTQATFSSGTSISSPHQFITSTNTFTDVST-------NPSTSLIMTES---S 4383

Query: 924  AKEMTTKLGVTAEYSPASRSLGTSPSP---QTTVVSTAEDLAPKSATFAVQS----STQS 976
               +TT+ G T   +     L TS  P   +T +  T + +  +  T   +     S  S
Sbjct: 4384 GVTITTQTGPTGAATQGPYLLDTSTMPYLTETPLAVTPDFMQSEKTTLISKGPKDVSWTS 4443

Query: 977  PTTVSSSASVNSCAVNPCLHNGECVADNTSRGYHCRCPPS 1016
            P +V+ ++  +S  + P L      A +T +G H   P S
Sbjct: 4444 PPSVAETSYPSS--LTPFLVTTIPPATSTLQGQHTSSPVS 4481



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 79/308 (25%), Positives = 125/308 (40%), Gaps = 43/308 (13%)

Query: 704 STSDASTP-WSSSPSPLPVSLTTSTSAPLSVSQTTLPQSSSTPVLPRARETPVTSFQTST 762
           S S  +TP   S  +   +S  TST A + V++ TLP +S    L     +P +S    T
Sbjct: 21  SRSTKATPEMDSGLTGATLSPKTSTGA-IVVTEHTLPFTSPDKTLA----SPTSSVVGRT 75

Query: 763 MTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTES 822
             S   M  SS   +  S+   H E+  + S SP +   P+ +  A +  S L    T +
Sbjct: 76  TQSLGVM--SSALPESTSRGMTHSEQRTSPSLSPQVNGTPSRNYPATSMVSGLSSPRTRT 133

Query: 823 STEQTLPATSTNLAQMSPTFTTTILKTSQPL---MTTPGTLSSTAS-------------- 865
           S      +T  N  + + T+T T+  TS P+    T P   S+T                
Sbjct: 134 S------STEGNFTKEASTYTLTVETTSGPVTEKYTVPTETSTTEGDSTETPWDTRYIPV 187

Query: 866 LVTGPIA--VQTTAGKQ---LSLTHPEILVPQISTEGGISTERNRVIVDATTGLIPLTSV 920
            +T P+     +TA K+   +S+T  E  V    T G  +      +  +   L P    
Sbjct: 188 KITSPMKTFADSTASKENAPVSMTPAETTVTDSHTPGRTNPSFG-TLYSSFLDLSP-KGT 245

Query: 921 PTSAKEMTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSATFAVQSSTQSPTTV 980
           P S  E + +L ++    P S     SP P +   S     AP S++ +V  +  S T++
Sbjct: 246 PNSRGETSLELILSTTGYPFS-----SPEPGSAGHSRISTSAPLSSSASVLDNKISETSI 300

Query: 981 SSSASVNS 988
            S  S+ S
Sbjct: 301 FSGQSLTS 308



 Score = 47.8 bits (112), Expect = 7e-05
 Identities = 125/570 (21%), Positives = 228/570 (40%), Gaps = 77/570 (13%)

Query: 133   FSTVSSKEGVMVQTSGKSHAASDAPENLTLLAETADARGR----SGSSSRTNF-TILPVG 187
             FS   S   + V  +     AS A    T+  + +D        SG+ + T F T+    
Sbjct: 11509 FSHSKSDTTLPVAITSPGPEASSAVSTTTISPDMSDLVTSLVPSSGTDTSTTFPTLSETP 11568

Query: 188   YSLEI-ATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTASEMGTERA-MGLSEE 245
             Y  E  AT LT  +    + S  +P+ S    +   +  T  G  +  G     +  S  
Sbjct: 11569 YEPETTATWLTHPAETSTTVSGTIPNFSHRGSDTAPSMVTSPGVDTRSGVPTTTIPPSIP 11628

Query: 246   WTVHSQEATTSAWSPSFLPAL--EMGE----------------LTTPSRKRNSSGPDL-- 285
               V SQ  +++  + + +P L    GE                 T P R   SS PD   
Sbjct: 11629 GVVTSQVTSSATDTSTAIPTLTPSPGEPETTASSATHPGTQTGFTVPIRTVPSSEPDTMA 11688

Query: 286   SWLHFYRTAASSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRS 345
             SW+  +    S+P+   +SS   +    ++T + ++S     +  V T  + G P  + S
Sbjct: 11689 SWVT-HPPQTSTPVSRTTSSFSHSSP--DATPVMATSPRTEASSAVLTTISPGAPEMVTS 11745

Query: 346   LTVSLGPVSKTE--------GFPKDSRIATT----SSSVLLSPSAV---ESRRNSRVTGN 390
                S G  + T         G P+ + + +T     +S     S V    S   + +T  
Sbjct: 11746 QITSSGAATSTTVPTLTHSPGMPETTALLSTHPRTETSKTFPASTVFPQVSETTASLTIR 11805

Query: 391   PGDEEFIEPSTENEFGLTSLRWQNDS-----PTFGEHQLASSSEVQNGSPMSQTETVSRS 445
             PG E      T+    L +L     S     PT      A ++ +    P ++T T+  +
Sbjct: 11806 PGAETSTALPTQTTSSLFTLLVTGTSRVDLSPTASPGVSAKTAPLST-HPGTETSTMIPT 11864

Query: 446   VAPMRGGEITAHWLLTNS---TTSADVTGSSASYPEGVNASVLTQFSDSTVQSGGSHTA- 501
                  G   T   L T+S   T+++ +T + +    G++++ +T     TV S  + T+ 
Sbjct: 11865 STLSLGLLETTGLLATSSSAETSTSTLTLTVSPAVSGLSSASITTDKPQTVTSWNTETSP 11924

Query: 502   ----LGDRSYSESSSTSSSESLNSSAPRGERSIAGISYGQ-VRGTAIEQRTSSDHTDHTY 556
                 +G   +S + + ++   + S  P   ++    S+G+ V  T I + T  + T+   
Sbjct: 11925 SVTSVGPPEFSRTVTGTTMTLIPSEMPTPPKT----SHGEGVSPTTILRTTMVEATN--- 11977

Query: 557   LSSTFTKGERALLSITDNSSSSDIVESSTS--YIKISNSSHSEYSSFFHAQTERSNISSY 614
             L++T +    A  + T N+ +  +    T+     +++ S +  +S+ H ++  S  SSY
Sbjct: 11978 LATTGSSPTVAKTTTTFNTLAGSLFTPLTTPGMSTLASESVTSRTSYNH-RSWISTTSSY 12036

Query: 615   DGEYAQPSTESPV-------LHTSNLPSYT 637
             +  Y  P+T +PV       + TS++PS T
Sbjct: 12037 NRRYWTPATSTPVTSTFSPGISTSSIPSST 12066



 Score = 41.2 bits (95), Expect = 0.007
 Identities = 95/366 (25%), Positives = 146/366 (39%), Gaps = 49/366 (13%)

Query: 612 SSYDGEYAQPSTESPVL----HTSNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSSS 667
           S   G    P T +  +    HT    S   T+  P +SVV  T       SS+   S+S
Sbjct: 32  SGLTGATLSPKTSTGAIVVTEHTLPFTSPDKTLASPTSSVVGRTTQSLGVMSSALPESTS 91

Query: 668 SSSSSGPPLPLPSVS-QSHHLFSSILPSTRASVHLLKS--TSDASTPWSSSPSPLPVSLT 724
              +       PS+S Q +   S   P+T + V  L S  T  +ST  + +      +LT
Sbjct: 92  RGMTHSEQRTSPSLSPQVNGTPSRNYPAT-SMVSGLSSPRTRTSSTEGNFTKEASTYTLT 150

Query: 725 TSTSAPLSVSQTTLPQSSSTPVLPRARETP-----VTSFQTSTMTSFMTMLHSSQTADLK 779
             T++     + T+P  +ST     + ETP     +    TS M +F     S + A + 
Sbjct: 151 VETTSGPVTEKYTVPTETST-TEGDSTETPWDTRYIPVKITSPMKTFADSTASKENAPV- 208

Query: 780 SQSTPHQEKVITESKSPSLVSLPTEST--KAVTTNSP--LPPSLTESSTEQTLPATSTNL 835
             S    E  +T+S +P   + P+  T   +    SP   P S  E+S E  L  T    
Sbjct: 209 --SMTPAETTVTDSHTPGRTN-PSFGTLYSSFLDLSPKGTPNSRGETSLELILSTTGYPF 265

Query: 836 AQMSPTFTTTILKTSQPLMTTPGTLSSTASLVTGPIAVQTTAGKQLSLTHPEILVPQIST 895
           +   P             ++T   LSS+AS++   I+ +T+     SLT P  L P +  
Sbjct: 266 SSPEPG------SAGHSRISTSAPLSSSASVLDNKIS-ETSIFSGQSLTSP--LSPGV-P 315

Query: 896 EGGISTERNRVIVDATTGLIPLTSVPTSAKEMTTKLGVTAEYSPASRSLGTSPSPQTTVV 955
           E   ST  N  I  + T    L++  TSA+ + + +           SLGT   P  +  
Sbjct: 316 EARASTMPNSAIPFSMT----LSNAETSAERVRSTIS----------SLGT---PSISTK 358

Query: 956 STAEDL 961
            TAE +
Sbjct: 359 QTAETI 364



 Score = 35.8 bits (81), Expect = 0.29
 Identities = 39/135 (28%), Positives = 54/135 (40%), Gaps = 7/135 (5%)

Query: 857 PGTLSSTASLVTGPIAVQTTAGKQLSLTHPEILVPQISTEGGISTERNRVIVDATTGLIP 916
           PG+ S T SL+TG  + + T      LT    L P+ ST   + TE           L  
Sbjct: 8   PGSSSPTRSLMTGSRSTKATPEMDSGLT-GATLSPKTSTGAIVVTEHTLPFTSPDKTLAS 66

Query: 917 LTSVPTSAKEMTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAEDL----APKSATFAVQS 972
            TS  +     T  LGV +   P S S G + S Q T  S +  +    +      ++ S
Sbjct: 67  PTS--SVVGRTTQSLGVMSSALPESTSRGMTHSEQRTSPSLSPQVNGTPSRNYPATSMVS 124

Query: 973 STQSPTTVSSSASVN 987
              SP T +SS   N
Sbjct: 125 GLSSPRTRTSSTEGN 139


>gi|239757995 PREDICTED: similar to hCG1747327, partial [Homo sapiens]
          Length = 1064

 Score = 90.9 bits (224), Expect = 8e-18
 Identities = 196/903 (21%), Positives = 345/903 (38%), Gaps = 111/903 (12%)

Query: 134  STVSSKEGVMVQTSGKSHAASDAPENLTLLAETADARGRSGSSSRTNFTILPVGYSLEIA 193
            +T + +  ++  T   S +A+D   + T+ + T         +   + T+ P      + 
Sbjct: 188  TTTARETPIVTVTPSSSVSATDTTFHTTISSTTRTTERTPLPTGSIHTTMSPTPVFTTLK 247

Query: 194  TALTSQSGNLAS-ESLHLPSSSSEFDERIAAFQTKSGTASEMGTERAMGLSEEWTVHSQE 252
            TA+TS S   ++  S +  +S +    R  A  T S   S + +   +  +E  T H+ +
Sbjct: 248  TAVTSTSPITSTITSTNTVTSMTTTTSRPTATNTLSSLMSNILSSTPVPSTEMTTSHTTD 307

Query: 253  ATTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASSPLLDLSSSSESTEKL 312
                +   + LP       TT +R   +S              + P    S+ ++ST ++
Sbjct: 308  TNPLSTLVTTLP-------TTITRSTPTS------------ETTYPASPTSTVTDSTTEI 348

Query: 313  NNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVSKTEGFPKDSRIATTSSSV 372
              ST L + ++S T T+          P T  S   +  P++ T      +   T+ SS+
Sbjct: 349  TYSTVL-TGTLSPTTTL----------PPTSSSQQTTETPMTPTTKLVTTTTETTSQSSL 397

Query: 373  LLSPSAVESRRNSRVT---------GNPGDEEFIEPSTENEFGLTSL-----RWQNDSPT 418
              S SA+ S  ++  T         G       I P+ + +  L  L     R Q  +P 
Sbjct: 398  NFSSSAIYSTVSTSTTAISSLPPTSGTMVTSTNIVPTADLKPELILLEVHDQRIQAKNPR 457

Query: 419  FGEHQLASSSEVQ---------NGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSAD- 468
            + +    SS+            N        T   S  P+    IT    +T+ TT+A  
Sbjct: 458  YSQTPFTSSTATSPETTTLTCTNDISTESLTTAMTSTTPVISA-ITPKTTVTSMTTTASG 516

Query: 469  ---------VTGSSASYPEGVNASVLTQFSDSTVQSGGSHTALGDRSYSESSSTSSSESL 519
                     +T S  S     N  V+T  + +T       T L     + + ST +SE+ 
Sbjct: 517  PTTTNTLSSLTSSILSSTPAPNTEVITSHTTTTTPPSTLVTTLPT---AIARSTPTSETT 573

Query: 520  NSSAPRGERSIAGISYGQVRGTAIEQRTSSDHTDHTYLSSTFTKGERALL--SITDNSSS 577
               +P G  + +         T I   TS   T  T  +   T      +  + T  ++ 
Sbjct: 574  YPISPTGTVTDSM--------TEITYSTSMTGTWSTATTLPLTSCSLPTIETATTPTTNL 625

Query: 578  SDIVESSTSYIKISNSSHSEYSSFFHAQTERSNISSYDGEYA-----QPSTESPVLHTSN 632
             +    +TS+   S +S + YS+   + T  S+     G         PS+ S  + T+ 
Sbjct: 626  GNTTTETTSHSTPSFTSSAIYSTVNISTTTISSFPPSSGTMVTFTTMNPSSLSTDISTTT 685

Query: 633  LPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSIL 692
            L + T         +   TD       SSSS+ S+S + S P +    +S      ++  
Sbjct: 686  LKNITQPSVGSTGFLTAATDLTSTFTVSSSSAMSTSVTPSAPSIQNKEISTLVSTTTTTS 745

Query: 693  PSTRASVHLLKSTSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQS-SSTPVLPRAR 751
            P+ R ++     TS  +TP S   +  PV+ + S S   S   TT  +S SS P +    
Sbjct: 746  PTERMTL-----TSTENTPTSYILTTSPVTYSFSPSMSASSDWTTDTESISSAPAITSTL 800

Query: 752  ETPVTSFQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTT 811
             T   S    T T+  T   + +       +T   +   T S +  L +     T  ++T
Sbjct: 801  HTTAESTLAPTTTNSFTTSANMEPPSTAVATTGTGQSTFTSSTATFLETTTLTPTTDIST 860

Query: 812  NSPLPP--SLTESSTEQTLPATSTNL--AQMSPTFTTTILK-TSQPLMTTP----GTLSS 862
             S + P  S T  ++  TL  T T++  A   PT T T+   TS  L +TP      ++S
Sbjct: 861  ESFMTPMISTTPITSSMTLRNTMTSMTTAASRPTTTNTLSSLTSSILSSTPVPSTEVITS 920

Query: 863  TASLVTGPIAVQTTAGKQLSLTHPEILVPQISTEGGISTERNRVIVDATTGLIPLTSVPT 922
              +  T P  + TT    ++ + P       ++E   ST     + D+TT     TS+  
Sbjct: 921  QTTNTTSPSTLVTTLPTTITTSTP-------TSETTYSTSPTSTVTDSTTETTYSTSITG 973

Query: 923  SAKEMTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSATFAV---QSSTQSPTT 979
            +   ++T++ + A  S       +  S +  V +T E+ +  + TF +    + + S T 
Sbjct: 974  T---LSTEISLPATTSSLITKGISMTSTRNLVTTTNENTSHSTPTFTLTIHSTISTSTTA 1030

Query: 980  VSS 982
            +SS
Sbjct: 1031 ISS 1033



 Score = 90.9 bits (224), Expect = 8e-18
 Identities = 179/796 (22%), Positives = 311/796 (39%), Gaps = 121/796 (15%)

Query: 150  SHAASDAPENLTLLAETADARGRSGSSSRTNFTILPVGYSLEIATALTSQS---GNLASE 206
            SH     P + TL+        RS  +S T +   P     +  T +T  +   G L+  
Sbjct: 303  SHTTDTNPLS-TLVTTLPTTITRSTPTSETTYPASPTSTVTDSTTEITYSTVLTGTLSPT 361

Query: 207  SLHLPSSSSEFDERIAAFQTKS--GTASEMGTERAMGLSEEWTVHSQEATTSA------- 257
            +   P+SSS+         T     T +E  ++ ++  S      +   +T+A       
Sbjct: 362  TTLPPTSSSQQTTETPMTPTTKLVTTTTETTSQSSLNFSSSAIYSTVSTSTTAISSLPPT 421

Query: 258  -----WSPSFLPALEMGE----LTTPSRKRNSSGPDLSWLHFYRTAASSPLL-------D 301
                  S + +P  ++      L    ++  +  P  S   F  + A+SP         D
Sbjct: 422  SGTMVTSTNIVPTADLKPELILLEVHDQRIQAKNPRYSQTPFTSSTATSPETTTLTCTND 481

Query: 302  LSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSL---GPVSKTEG 358
            +S+ S +T   + +  + + +   T T    T        TL SLT S+    P   TE 
Sbjct: 482  ISTESLTTAMTSTTPVISAITPKTTVTSMTTTASGPTTTNTLSSLTSSILSSTPAPNTEV 541

Query: 359  FPKDSRIATTSSSVLLS-PSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQND-- 415
                +   T  S+++ + P+A+     +  T  P     I P+      +T + +     
Sbjct: 542  ITSHTTTTTPPSTLVTTLPTAIARSTPTSETTYP-----ISPTGTVTDSMTEITYSTSMT 596

Query: 416  ------------SPTFGEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNS 463
                        S +    + A++     G+  + TET S S        I +   ++ +
Sbjct: 597  GTWSTATTLPLTSCSLPTIETATTPTTNLGN--TTTETTSHSTPSFTSSAIYSTVNISTT 654

Query: 464  TTSAD----------VTGSSASYPEGVNASVLTQFSDSTVQSGGSHTALGD--RSYSESS 511
            T S+            T + +S    ++ + L   +  +V S G  TA  D   +++ SS
Sbjct: 655  TISSFPPSSGTMVTFTTMNPSSLSTDISTTTLKNITQPSVGSTGFLTAATDLTSTFTVSS 714

Query: 512  STSSSESLNSSAPRGERSIAGISYGQVRGTAIEQRTSSDHTDHTYLSSTFTKG--ERALL 569
            S++ S S+  SAP                 +I+ +  S     T +S+T T    ER  L
Sbjct: 715  SSAMSTSVTPSAP-----------------SIQNKEIS-----TLVSTTTTTSPTERMTL 752

Query: 570  SITDNSSSSDIVESSTSYIKISNSSHSEYSSFFHAQTERSNISSYDGEYAQPSTESPVLH 629
            + T+N+ +S I+  +TS +  S S     SS +   TE  + +         + ES +  
Sbjct: 753  TSTENTPTSYIL--TTSPVTYSFSPSMSASSDWTTDTESISSAPAITSTLHTTAESTLAP 810

Query: 630  TSNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFS 689
            T+   S+T + NM   S  + T     +  S+ +SS+++   +    P   +S    +  
Sbjct: 811  TTT-NSFTTSANMEPPSTAVATTG---TGQSTFTSSTATFLETTTLTPTTDISTESFMTP 866

Query: 690  SILPSTRASVHLLKSTSDASTPWSSSP------SPLPVSLTTSTSAPLS---VSQTTLPQ 740
             I  +   S   L++T  + T  +S P      S L  S+ +ST  P +    SQTT   
Sbjct: 867  MISTTPITSSMTLRNTMTSMTTAASRPTTTNTLSSLTSSILSSTPVPSTEVITSQTTNTT 926

Query: 741  SSSTPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVS 800
            S ST V      T  T+  TST TS  T   +S T+ +   +T       T   +    +
Sbjct: 927  SPSTLVT-----TLPTTITTSTPTS-ETTYSTSPTSTVTDSTTE------TTYSTSITGT 974

Query: 801  LPTESTKAVTTNSPLPPSLTESSTEQTLPATSTNLAQMSPTFTTTILKTSQPLMTTPGTL 860
            L TE +   TT+S +   ++ +ST   +  T+ N +  +PTFT TI  T    ++T  T 
Sbjct: 975  LSTEISLPATTSSLITKGISMTSTRNLVTTTNENTSHSTPTFTLTIHST----ISTSTTA 1030

Query: 861  SSTASLVTGPIAVQTT 876
             S+    +GPI   TT
Sbjct: 1031 ISSVPTTSGPIVTSTT 1046



 Score = 79.0 bits (193), Expect = 3e-14
 Identities = 102/416 (24%), Positives = 181/416 (43%), Gaps = 55/416 (13%)

Query: 621  PSTESPVLHTSNLPSYTPT-------INMPNTSVVLDTDAEFVSDSSSSSS--------- 664
            P T+ PV   +     T T       I+ P+T+   +T    V+ SSS S+         
Sbjct: 157  PVTQKPVTTVTRTYPMTTTEKGTSAMISSPSTTTARETPIVTVTPSSSVSATDTTFHTTI 216

Query: 665  SSSSSSSSGPPLPLPSVSQSHHLFSSILPSTRASVHLLKSTSDASTPWSSSPSPLPVSLT 724
            SS++ ++   PLP  S+    H   S  P        + STS  ++  +S+ +    S+T
Sbjct: 217  SSTTRTTERTPLPTGSI----HTTMSPTPVFTTLKTAVTSTSPITSTITSTNT--VTSMT 270

Query: 725  TSTSAPLSVSQTTLPQS---SSTPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADLKSQ 781
            T+TS P + +  +   S   SSTPV P    T   +  T+ +++ +T L ++ T     +
Sbjct: 271  TTTSRPTATNTLSSLMSNILSSTPV-PSTEMTTSHTTDTNPLSTLVTTLPTTIT-----R 324

Query: 782  STPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESSTEQTLPATSTNLAQMSPT 841
            STP  E     S + ++    TE T +      L P+ T   T  +   T T +   +  
Sbjct: 325  STPTSETTYPASPTSTVTDSTTEITYSTVLTGTLSPTTTLPPTSSSQQTTETPMTPTTKL 384

Query: 842  FTTTILKTSQ-PLMTTPGTLSSTASLVTGPI-AVQTTAGKQLSLTH--------PEILVP 891
             TTT   TSQ  L  +   + ST S  T  I ++  T+G  ++ T+        PE+++ 
Sbjct: 385  VTTTTETTSQSSLNFSSSAIYSTVSTSTTAISSLPPTSGTMVTSTNIVPTADLKPELILL 444

Query: 892  QISTEGGISTERNRVIVDATTGLIPLTSVPTSAKEMTTKLGVTAEYSPASRSLGTSPSPQ 951
            ++  +  I  +  R          P TS   ++ E TT   +T     ++ SL T+ +  
Sbjct: 445  EVHDQ-RIQAKNPRY------SQTPFTSSTATSPETTT---LTCTNDISTESLTTAMTST 494

Query: 952  TTVVSTAEDLAPKSATFAVQSSTQSPTTVSSSASVNSCAVNPC-LHNGECVADNTS 1006
            T V+S    + PK+   ++ ++   PTT ++ +S+ S  ++     N E +  +T+
Sbjct: 495  TPVISA---ITPKTTVTSMTTTASGPTTTNTLSSLTSSILSSTPAPNTEVITSHTT 547



 Score = 37.7 bits (86), Expect = 0.077
 Identities = 54/207 (26%), Positives = 86/207 (41%), Gaps = 26/207 (12%)

Query: 790 ITESKSPSLVSLP-TESTKAVTTNSPLPPSLTESSTEQTLPATSTNLAQMSPTFTTTILK 848
           ++ + S S V+ P  E+T+   +NSP    L E    Q +P  ++           T+  
Sbjct: 19  LSTATSTSHVTFPRAEATRTALSNSPHSRYLAE--WPQGVPQLASPAPGHRENAPMTLTT 76

Query: 849 TSQPLMTTPGTLSSTASLVTGPIAVQTTAGKQLSLTHPEILVPQISTEGGISTERNRVIV 908
           +    + +   LSS  S  T        A K +  T P +LV   +TE           V
Sbjct: 77  SPHDTLISETLLSSLVSSNTSTTPTSKFAFK-VETTPPTVLVYLATTE----------CV 125

Query: 909 DATTGLIPLTSVPTSAKEMTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSATF 968
             T+ +I + S PTS    TT++  T+ Y+P       +  P TTV  T      +  T 
Sbjct: 126 YPTSFIITI-SHPTSICVTTTQVTFTSSYTPTP----VTQKPVTTVTRTYPMTTTEKGTS 180

Query: 969 AVQSSTQSPT-------TVSSSASVNS 988
           A+ SS  + T       TV+ S+SV++
Sbjct: 181 AMISSPSTTTARETPIVTVTPSSSVSA 207


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 90.9 bits (224), Expect = 8e-18
 Identities = 161/729 (22%), Positives = 292/729 (40%), Gaps = 26/729 (3%)

Query: 116  NTEAHVENITFYQNQEDFSTVSSKEGVMVQTSGKSHAASDAPENLTLLAETADARGRSGS 175
            N +A+ E+     ++ D S  +S E         S  A D   + T     +D+ G   +
Sbjct: 474  NDDANSESDNNSSSRGDAS-YNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNN 532

Query: 176  SSRTNFTILPVGYSLEIATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTASEMG 235
             +  N          + + + +S S N +  S    S SS+ +       +    +S+  
Sbjct: 533  GNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNS------SSDSDSSDSD 586

Query: 236  TERAMGLSEEWTVHSQEATTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAA 295
            +  +       + +S +++ S+ S     + +  +  + S K  S   D         + 
Sbjct: 587  SSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSN 646

Query: 296  SSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVSK 355
            SS   D S SS+S+   N+S    SS  S + +   ++  +D    +  S +      S 
Sbjct: 647  SSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSD 706

Query: 356  TEGFPKDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQND 415
            +     DS  ++ SS+   S S   +  +S  + N  D      S+ +     S    N 
Sbjct: 707  SSD--SDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNS 764

Query: 416  SPTFGEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADVTGSSAS 475
            S +      + SS+  N S  + +   S S       + +      NS+ S+D + SS S
Sbjct: 765  SDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSS------NSSDSSDSSDSSDS 818

Query: 476  YPEGVNASVLTQFSDSTVQSGGSHTALGDRSY--SESSSTSSSESLNSSAPRGERSIAGI 533
              +  N+S  +  SDS+  S  S ++    S   S+S S++ S+S NSS        +  
Sbjct: 819  --DSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNS 876

Query: 534  SYGQVRGTAIEQRTSSDHTDHTYLSSTFTKGERALLSITDNSSSSDIVESSTSYIKISNS 593
            S       + E   SSD +D +  S + +         +D+S+SSD  ESS S    SNS
Sbjct: 877  SDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDN-SNS 935

Query: 594  SHSEYSSFFHAQTERSNISSYDGEYAQPSTESPVLHTSNLPSYTPTINMPNTSVVLDT-D 652
            S S  SS     ++ SN S  D   +  S+ S     SN    + + N  ++S   D+ D
Sbjct: 936  SDSSNSSDSSDSSDSSNSS--DSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSD 993

Query: 653  AEFVSDSSSSSSS--SSSSSSSGPPLPLPSVSQSHHLFSSILPSTRASVHLLKSTSDAST 710
            +   SDSS+SS S  SS SS S       + S S +   S   S  +       +SD+S 
Sbjct: 994  SSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD 1053

Query: 711  PWSSSPSPLPVSLTTSTSAPLSVSQTTLPQSSSTPVLPRARETPVTSFQTSTMTSFMTML 770
              +SS S      + S+ +  S   +   +SS +     + ++  +S  +S  +      
Sbjct: 1054 SSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSS-DSSDSSDSSDSS 1112

Query: 771  HSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESSTEQTLPA 830
             SS ++D  + S        ++S   S  S  ++S+++  ++     S +  S++ +  +
Sbjct: 1113 DSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSS 1172

Query: 831  TSTNLAQMS 839
             S++ +  S
Sbjct: 1173 DSSDSSNSS 1181



 Score = 75.9 bits (185), Expect = 3e-13
 Identities = 120/559 (21%), Positives = 224/559 (40%), Gaps = 32/559 (5%)

Query: 129  NQEDFSTVSSKEGVMVQTSGKSHAASDAPENLTLLAETADARGRSGSSSRTNFTILPVGY 188
            N  D  + +S +      S  S  +SD+  N +  ++++D+   S SS  ++        
Sbjct: 722  NSSDSDSSNSSDSSDSSNSSDSSDSSDS-SNSSDSSDSSDSSNSSDSSDSSD-------- 772

Query: 189  SLEIATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTASEMGTERAMGLSEEWTV 248
            S + + +  S   N +S S     SS+  D   ++  + S  +S+  +  +   S   + 
Sbjct: 773  SSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSN--SS 830

Query: 249  HSQEATTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASSPLLDLSSSSES 308
             S +++ S+ S     + +  +  + +R  +S+  D S      ++ SS   D S SS+S
Sbjct: 831  DSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSS-----DSSDSSNSSDSSDSSDS 885

Query: 309  TEKLN--------NSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVSKTEGFP 360
             E  N        NS+   SS  S +     ++  +D    +  S   +    S +    
Sbjct: 886  NESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSS 945

Query: 361  KDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQNDSPTFG 420
              S  + +S S   S S+  S  +   + +  D      S+++     S    + S +  
Sbjct: 946  DSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSD 1005

Query: 421  EHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADVTGSSASYPEGV 480
                + SS+  N S  S +   S S       + +     ++S+ S+D + SS S  +  
Sbjct: 1006 SSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDS-SDSS 1064

Query: 481  NASVLTQFSDSTVQSGGSHTALGDRSYSESSSTSSSESLNSSAPRGERSIAGISYGQVRG 540
            ++S  +  SDS+  S  S ++    S + S S+ SS+S +SS        +  S      
Sbjct: 1065 DSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSS 1124

Query: 541  TAIEQRTSSDHTDHTYLSSTFTKGERALLS-------ITDNSSSSDIVESSTSYIKISNS 593
             + +   SSD +D +  S +    E +  S        +D+S SSD  +SS S     +S
Sbjct: 1125 DSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSS 1184

Query: 594  SHSEYSSFFHAQTERSNISSYDGEYAQPSTESPVLHTSNLPSYTPTINMPNTSVVLDTDA 653
              S+ S    +     +  S D   +  S++S     S+  S +   N  + S      +
Sbjct: 1185 DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSS 1244

Query: 654  EFVSDSSSSSSSSSSSSSS 672
            +  + S SS SS SS S+S
Sbjct: 1245 DSSNSSDSSDSSDSSDSTS 1263



 Score = 68.6 bits (166), Expect = 4e-11
 Identities = 115/536 (21%), Positives = 207/536 (38%), Gaps = 22/536 (4%)

Query: 129  NQEDFSTVSSKEGVMVQTSGKSHAASDAPENLTLLAETADARGRSGSSSRTNFTILPVGY 188
            N    S+ SS       +S  S ++  +  + +  + ++D+   S SS  +N +      
Sbjct: 786  NDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSS--DSSD 843

Query: 189  SLEIATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTASEMGTERAMGLSEEWTV 248
            S + +    S S N +  S    SS S      +     S +     +  +   S     
Sbjct: 844  SSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDS 903

Query: 249  HSQEATTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASSPLLDLSSSSES 308
             S +++ S+ S     + +  E +  S   NSS           ++ SS   D S SS S
Sbjct: 904  DSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSD----------SSNSSDSSDSSDSSNS 953

Query: 309  TEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVSKTEGFPKDSRIATT 368
            ++  N+S    SS  S + +   +   +     +  S   S    S       DS  ++ 
Sbjct: 954  SDSSNSSDSSNSSDSSDSNSSDSSD--SSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD 1011

Query: 369  SSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQNDSPTFGEHQLASSS 428
            SS    S  +  S  +S  + +  D      S+++     S    N S +      + SS
Sbjct: 1012 SSDSSNSSDSSNSSDSSN-SSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1070

Query: 429  EVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADVTGSSASYPEGVNASVLTQF 488
            +  + S  S +   S S       + +     ++S+ S+D + SS S  +  N+S  +  
Sbjct: 1071 DSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS-SDSSNSSDSSDS 1129

Query: 489  SDSTVQSGGSHTALGDRSYSESSSTSSSESLNSSAPRGERSIAGISYGQVRGTAIEQRTS 548
            SDS+  S  S+++    S   S S+ SS+S +SS        +  S       + +   S
Sbjct: 1130 SDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDS 1189

Query: 549  SDHTDHTYLSSTFTKGERALLSITDNSSSSDIVESSTSYIKISNSSHSEYSSFFHAQTER 608
            SD +D +  S +    + +     D+S SSD  +SS S     +S  +E S    +    
Sbjct: 1190 SDSSDSSDSSDSSDSSDSS-----DSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSS 1244

Query: 609  SNISSYDGEYAQPSTESPVLHTSNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSS 664
             + +S D   +  S++S         S + + N  N     D+D+E  SDS+ S+S
Sbjct: 1245 DSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSE-GSDSNHSTS 1299



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 92/414 (22%), Positives = 179/414 (43%), Gaps = 19/414 (4%)

Query: 461 TNSTTSADVTGSS---------ASYPEGVNASVLTQFSDSTVQSGGSHTALGDRSYSESS 511
           T+ T ++D  G+          +   +G + S  +  SDS+  S  S ++  D S S SS
Sbjct: 518 TSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSS 577

Query: 512 STSSSESLNSSAPRGERSIAGISYGQVRGTAIEQRTSSDHTDHTYLSSTFTKGERALLSI 571
           S S S   +SS    + S +  S       + +   SSD +D +  S + +   ++    
Sbjct: 578 SDSDSSDSDSS----DSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDS 633

Query: 572 TDNSSSSDIVESSTSYIKISNSSHSEYSSFFHAQTERSNISSYDGEYAQPSTESPVLHTS 631
           +D+ S SD  +S++S    ++ S    +S   + +  S+ SS     +  S  S    +S
Sbjct: 634 SDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSS 693

Query: 632 NLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSI 691
           +  + + + +  ++S   D+D+   SDSS+S+SS S SS+S       + S S     S 
Sbjct: 694 DSSNSSESSDSSDSS---DSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSS 750

Query: 692 LPSTRASVHLLKSTSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQSSSTPVLPRAR 751
             S  +      ++SD+S   SS  S    S  +S S   S S  +   S+S+     + 
Sbjct: 751 NSSDSSDSSDSSNSSDSSD--SSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSD 808

Query: 752 ETPVTSFQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTT 811
            +  +    S  ++     +SS ++D  S S+   +   +   S S  S  ++S+ +  +
Sbjct: 809 SSDSSDSSDSDSSNSSDSSNSSDSSD-SSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDS 867

Query: 812 NSPLPPSLTESSTEQTLPATSTNLAQMSPTFTTTILKTSQPLMTTPGTLSSTAS 865
           +     S +  S++ +    S+N +  S +  ++   +S    ++  + SS +S
Sbjct: 868 SDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSS 921



 Score = 58.2 bits (139), Expect = 5e-08
 Identities = 101/486 (20%), Positives = 194/486 (39%), Gaps = 26/486 (5%)

Query: 116  NTEAHVENITFYQNQEDFSTVSSKEGVMVQTSGKSHAASDAPENLTLLAETADARGRSGS 175
            ++++   N +   N  D S+ SS       +S  S  +     N +  + ++D+   S S
Sbjct: 815  SSDSDSSNSSDSSNSSD-SSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDS 873

Query: 176  SSRTNFTILPVGYSLEIATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTASEMG 235
            S+ ++ +          ++  +  S +  S+S    +SS   D   ++  ++S  +S+  
Sbjct: 874  SNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNS 933

Query: 236  TERAMGLSEEWTVHSQEATTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAA 295
                   S +    S +++ S+ S     + +    +  S   +S   D S      ++ 
Sbjct: 934  NSSDSSNSSD----SSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSS-----NSSD 984

Query: 296  SSPLLDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVSK 355
            SS   D S SS+S++  N+S    SS  S +     ++  +D       S   S    S 
Sbjct: 985  SSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSS----NSSDSSDSSDSS 1040

Query: 356  TEGFPKDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQND 415
                  DS  ++ SS+   S  + +S  +S  + +    +  E S  ++         N 
Sbjct: 1041 DSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSS-------NS 1093

Query: 416  SPTFGEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADVTGSSAS 475
            S +      + SS+  + S  S +   S S       + +     +NS+ S+D + SS S
Sbjct: 1094 SDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDS 1153

Query: 476  YPEGVNASVLTQFSDSTVQSGGSHTALGDRSYSESSSTSSSESLNSSAPRGERSIAGISY 535
                 ++S  +  SDS+  S  S ++    S   S S+ SS+S +SS        +  S 
Sbjct: 1154 S----DSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1209

Query: 536  GQVRGTAIEQRTSSDHTDHTYLSSTFTKGERALLSITDNSS-SSDIVESSTSYIKISNSS 594
                  + +   SSD +D +  + +    + +  S + NSS SSD  +SS S    ++ S
Sbjct: 1210 SSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDES 1269

Query: 595  HSEYSS 600
             S+  S
Sbjct: 1270 DSQSKS 1275



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 104/522 (19%), Positives = 208/522 (39%), Gaps = 64/522 (12%)

Query: 488 FSDSTVQSGGSHTALGDRSYSESSSTSSSESLNSSAPRGERSIAGISYGQVRGTAIEQRT 547
           F D ++Q    +++      S  +  ++SES N+S+ RG+ S       +  G   + + 
Sbjct: 455 FDDKSMQGDDPNSS----DESNGNDDANSESDNNSSSRGDASY-NSDESKDNGNGSDSKG 509

Query: 548 SSD---------------------HTDHTYLSSTFTKGERALLSITDNSSSSDIVESSTS 586
           + D                     + D+    S   K + +    +D+S+SSD  +SS S
Sbjct: 510 AEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDS 569

Query: 587 YIKISNSSHSEYSSFFHAQTERSNISSYDGEYAQPSTESPVLHTSNLPSYTPTINMPNTS 646
               SNSS    SS   +     + SS     +  S  S    +S+    + + +  + S
Sbjct: 570 DSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKS 629

Query: 647 VVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSSILPSTRASVHLLKSTS 706
               +D++  SDSS S+SS SS +S          S S +  +S   S  +      S+S
Sbjct: 630 ESDSSDSDSKSDSSDSNSSDSSDNSDS--------SDSSNSSNSSDSSDSSDSSDSSSSS 681

Query: 707 DASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLPQSSSTPVLPRARETPVTSFQTSTMTSF 766
           D+S    SS S    S ++++S     S ++   SS +     +  +   S  +S  +  
Sbjct: 682 DSSNSSDSSDS----SDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDS 737

Query: 767 MTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKAVTTNSPLPPSLTESSTEQ 826
                SS ++D  + S        + S   S  S  ++S+ +  ++     S +  S++ 
Sbjct: 738 SNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDS 797

Query: 827 TLPATSTNLAQMSPTFTTTILKTSQPLMTTPGTLSSTASLVTGPIAVQTTAGKQLSLTHP 886
           +  + S+N +  S +  ++   +S    ++  + SS +S                     
Sbjct: 798 SNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSS------------------NSS 839

Query: 887 EILVPQISTEGGISTERNRVIVDATTGLIPLTSVPTSAKEMTTKLGVTAEYSPASRSLGT 946
           +      S++G  S   NR   D++       S  +S    ++    +++ S ++ S  +
Sbjct: 840 DSSDSSDSSDGSDSDSSNR--SDSS------NSSDSSDSSDSSNSSDSSDSSDSNESSNS 891

Query: 947 SPSPQTTVVSTAEDLAPKSATFAVQSSTQSPTTVSSSASVNS 988
           S S  ++  S ++     +++ +  SS  S ++ SS++S NS
Sbjct: 892 SDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNS 933


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.309    0.123    0.351 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 55,979,793
Number of Sequences: 37866
Number of extensions: 2966919
Number of successful extensions: 35642
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 368
Number of HSP's successfully gapped in prelim test: 1334
Number of HSP's that attempted gapping in prelim test: 17765
Number of HSP's gapped (non-prelim): 9886
length of query: 1381
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1266
effective length of database: 13,892,928
effective search space: 17588446848
effective search space used: 17588446848
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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