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Search of human proteins with 153791733
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|153791733 casein kinase 1, gamma 2 [Homo sapiens]
(415 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|153791733 casein kinase 1, gamma 2 [Homo sapiens] 857 0.0
gi|113462008 casein kinase 1, gamma 3 isoform 3 [Homo sapiens] 702 0.0
gi|73532780 casein kinase 1, gamma 3 isoform 2 [Homo sapiens] 693 0.0
gi|73532778 casein kinase 1, gamma 3 isoform 1 [Homo sapiens] 686 0.0
gi|98986450 casein kinase 1, gamma 1 [Homo sapiens] 685 0.0
gi|113462010 casein kinase 1, gamma 3 isoform 4 [Homo sapiens] 677 0.0
gi|23199991 casein kinase 1 epsilon [Homo sapiens] 361 e-100
gi|4503093 casein kinase 1 epsilon [Homo sapiens] 361 e-100
gi|20544145 casein kinase 1, delta isoform 2 [Homo sapiens] 359 2e-99
gi|20149530 casein kinase 1, delta isoform 1 [Homo sapiens] 359 2e-99
gi|68303572 casein kinase 1, alpha 1 isoform 2 [Homo sapiens] 329 3e-90
gi|68303575 casein kinase 1, alpha 1 isoform 1 [Homo sapiens] 323 2e-88
gi|21624639 casein kinase 1, alpha 1-like [Homo sapiens] 316 2e-86
gi|58761548 tau tubulin kinase 1 [Homo sapiens] 160 2e-39
gi|116812624 tau tubulin kinase 2 [Homo sapiens] 157 2e-38
gi|4507903 vaccinia related kinase 1 [Homo sapiens] 120 2e-27
gi|194440713 vaccinia related kinase 2 isoform 3 [Homo sapiens] 100 3e-21
gi|194440711 vaccinia related kinase 2 isoform 2 [Homo sapiens] 100 3e-21
gi|194440709 vaccinia related kinase 2 isoform 1 [Homo sapiens] 100 3e-21
gi|194440707 vaccinia related kinase 2 isoform 1 [Homo sapiens] 100 3e-21
gi|71164884 vaccinia related kinase 2 isoform 1 [Homo sapiens] 100 3e-21
gi|209862855 vaccinia related kinase 2 isoform 6 [Homo sapiens] 89 1e-17
gi|71164888 vaccinia related kinase 3 isoform 2 [Homo sapiens] 83 5e-16
gi|71164886 vaccinia related kinase 3 isoform 1 [Homo sapiens] 83 5e-16
gi|239756427 PREDICTED: similar to 3-phosphoinositide dependent ... 73 4e-13
gi|4505695 3-phosphoinositide dependent protein kinase-1 isoform... 73 5e-13
gi|239745384 PREDICTED: hypothetical protein XP_002343452 [Homo ... 73 5e-13
gi|38327572 serine/threonine protein kinase 6 [Homo sapiens] 67 3e-11
gi|38327570 serine/threonine protein kinase 6 [Homo sapiens] 67 3e-11
gi|38327568 serine/threonine protein kinase 6 [Homo sapiens] 67 3e-11
>gi|153791733 casein kinase 1, gamma 2 [Homo sapiens]
Length = 415
Score = 857 bits (2214), Expect = 0.0
Identities = 415/415 (100%), Positives = 415/415 (100%)
Query: 1 MDFDKKGGKGETEEGRRMSKAGGGRSSHGIRSSGTSSGVLMVGPNFRVGKKIGCGNFGEL 60
MDFDKKGGKGETEEGRRMSKAGGGRSSHGIRSSGTSSGVLMVGPNFRVGKKIGCGNFGEL
Sbjct: 1 MDFDKKGGKGETEEGRRMSKAGGGRSSHGIRSSGTSSGVLMVGPNFRVGKKIGCGNFGEL 60
Query: 61 RLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLSATEGVPQVYYFGPCGKYNAMVLE 120
RLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLSATEGVPQVYYFGPCGKYNAMVLE
Sbjct: 61 RLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLSATEGVPQVYYFGPCGKYNAMVLE 120
Query: 121 LLGPSLEDLFDLCDRTFTLKTVLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGRPGTKR 180
LLGPSLEDLFDLCDRTFTLKTVLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGRPGTKR
Sbjct: 121 LLGPSLEDLFDLCDRTFTLKTVLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGRPGTKR 180
Query: 181 QHAIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGH 240
QHAIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGH
Sbjct: 181 QHAIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGH 240
Query: 241 MFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEEMATYLRYVRRLDFF 300
MFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEEMATYLRYVRRLDFF
Sbjct: 241 MFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEEMATYLRYVRRLDFF 300
Query: 301 EKPDYDYLRKLFTDLFDRSGFVFDYEYDWAGKPLPTPIGTVHTDLPSQPQLRDKTQPHSK 360
EKPDYDYLRKLFTDLFDRSGFVFDYEYDWAGKPLPTPIGTVHTDLPSQPQLRDKTQPHSK
Sbjct: 301 EKPDYDYLRKLFTDLFDRSGFVFDYEYDWAGKPLPTPIGTVHTDLPSQPQLRDKTQPHSK 360
Query: 361 NQALNSTNGELNADDPTAGHSNAPITAPAEVEVADETKCCCFFKRRKRKSLQRHK 415
NQALNSTNGELNADDPTAGHSNAPITAPAEVEVADETKCCCFFKRRKRKSLQRHK
Sbjct: 361 NQALNSTNGELNADDPTAGHSNAPITAPAEVEVADETKCCCFFKRRKRKSLQRHK 415
>gi|113462008 casein kinase 1, gamma 3 isoform 3 [Homo sapiens]
Length = 415
Score = 702 bits (1812), Expect = 0.0
Identities = 350/418 (83%), Positives = 375/418 (89%), Gaps = 11/418 (2%)
Query: 4 DKKGGKGETEEGRRMSKAGGGRSSHGIRSSGTSS-GVLMVGPNFRVGKKIGCGNFGELRL 62
+KK K ++++ RM++ G RS H R +G+SS GVLMVGPNFRVGKKIGCGNFGELRL
Sbjct: 3 NKKKDKDKSDD--RMARPSG-RSGHNTRGTGSSSSGVLMVGPNFRVGKKIGCGNFGELRL 59
Query: 63 GKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLSATEGVPQVYYFGPCGKYNAMVLELL 122
GKNLYTNEYVAIKLEP+KSRAPQLHLEYRFYKQL + +G+PQVYYFGPCGKYNAMVLELL
Sbjct: 60 GKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSGDGIPQVYYFGPCGKYNAMVLELL 119
Query: 123 GPSLEDLFDLCDRTFTLKTVLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGRPGTKRQH 182
GPSLEDLFDLCDRTF+LKTVLMIAIQLI+RMEYVH+K+LIYRDVKPENFL+GRPG K Q
Sbjct: 120 GPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNKTQQ 179
Query: 183 AIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMF 242
IHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMF
Sbjct: 180 VIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMF 239
Query: 243 MYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEEMATYLRYVRRLDFFEK 302
MYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFP EMATYLRYVRRLDFFEK
Sbjct: 240 MYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFP-EMATYLRYVRRLDFFEK 298
Query: 303 PDYDYLRKLFTDLFDRSGFVFDYEYDWAGKPLPTPIGTVHTD--LPSQ---PQLRDKTQP 357
PDYDYLRKLFTDLFDR G++FDYEYDW GK LPTP+G V D L S Q RDK Q
Sbjct: 299 PDYDYLRKLFTDLFDRKGYMFDYEYDWIGKQLPTPVGAVQQDPALSSNREAHQHRDKMQ- 357
Query: 358 HSKNQALNSTNGELNADDPTAGHSNAPITAPAEVEVADETKCCCFFKRRKRKSLQRHK 415
SKNQ ++STNGELN DDPTAG SNAPITAP EVEV DETKCCCFFKRRKRK++QRHK
Sbjct: 358 QSKNQVVSSTNGELNTDDPTAGRSNAPITAPTEVEVMDETKCCCFFKRRKRKTIQRHK 415
>gi|73532780 casein kinase 1, gamma 3 isoform 2 [Homo sapiens]
Length = 423
Score = 693 bits (1788), Expect = 0.0
Identities = 349/426 (81%), Positives = 374/426 (87%), Gaps = 19/426 (4%)
Query: 4 DKKGGKGETEEGRRMSKAGGGRSSHGIRSSGTSS-GVLMVGPNFRVGKKIGCGNFGELRL 62
+KK K ++++ RM++ G RS H R +G+SS GVLMVGPNFRVGKKIGCGNFGELRL
Sbjct: 3 NKKKDKDKSDD--RMARPSG-RSGHNTRGTGSSSSGVLMVGPNFRVGKKIGCGNFGELRL 59
Query: 63 GKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLSATEGVPQVYYFGPCGKYNAMVLELL 122
GKNLYTNEYVAIKLEP+KSRAPQLHLEYRFYKQL + +G+PQVYYFGPCGKYNAMVLELL
Sbjct: 60 GKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSGDGIPQVYYFGPCGKYNAMVLELL 119
Query: 123 GPSLEDLFDLCDRTFTLKTVLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGRPGTKRQH 182
GPSLEDLFDLCDRTF+LKTVLMIAIQLI+RMEYVH+K+LIYRDVKPENFL+GRPG K Q
Sbjct: 120 GPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNKTQQ 179
Query: 183 AIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMF 242
IHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMF
Sbjct: 180 VIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMF 239
Query: 243 MYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEEMATYLRYVRRLDFFEK 302
MYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFP EMATYLRYVRRLDFFEK
Sbjct: 240 MYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFP-EMATYLRYVRRLDFFEK 298
Query: 303 PDYDYLRKLFTDLFDRSGFVFDYEYDWAGKPLPTPIGTVHTD--LPSQ---PQLRDKTQP 357
PDYDYLRKLFTDLFDR G++FDYEYDW GK LPTP+G V D L S Q RDK Q
Sbjct: 299 PDYDYLRKLFTDLFDRKGYMFDYEYDWIGKQLPTPVGAVQQDPALSSNREAHQHRDKMQ- 357
Query: 358 HSKNQALNSTNGELNADDPTAGHSNAPITAPAEVEVADETK--------CCCFFKRRKRK 409
SKNQ ++STNGELN DDPTAG SNAPITAP EVEV DET CCCFFKRRKRK
Sbjct: 358 QSKNQVVSSTNGELNTDDPTAGRSNAPITAPTEVEVMDETNCQKVLNMWCCCFFKRRKRK 417
Query: 410 SLQRHK 415
++QRHK
Sbjct: 418 TIQRHK 423
>gi|73532778 casein kinase 1, gamma 3 isoform 1 [Homo sapiens]
Length = 447
Score = 686 bits (1770), Expect = 0.0
Identities = 350/450 (77%), Positives = 376/450 (83%), Gaps = 43/450 (9%)
Query: 4 DKKGGKGETEEGRRMSKAGGGRSSHGIRSSGTSS-GVLMVGPNFRVGKKIGCGNFGELRL 62
+KK K ++++ RM++ G RS H R +G+SS GVLMVGPNFRVGKKIGCGNFGELRL
Sbjct: 3 NKKKDKDKSDD--RMARPSG-RSGHNTRGTGSSSSGVLMVGPNFRVGKKIGCGNFGELRL 59
Query: 63 GKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLSATEGVPQVYYFGPCGKYNAMVLELL 122
GKNLYTNEYVAIKLEP+KSRAPQLHLEYRFYKQL + +G+PQVYYFGPCGKYNAMVLELL
Sbjct: 60 GKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSGDGIPQVYYFGPCGKYNAMVLELL 119
Query: 123 GPSLEDLFDLCDRTFTLKTVLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGRPGTKRQH 182
GPSLEDLFDLCDRTF+LKTVLMIAIQLI+RMEYVH+K+LIYRDVKPENFL+GRPG K Q
Sbjct: 120 GPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNKTQQ 179
Query: 183 AIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMF 242
IHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMF
Sbjct: 180 VIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMF 239
Query: 243 MYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEEMATYLRYVRRLDFFEK 302
MYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFP EMATYLRYVRRLDFFEK
Sbjct: 240 MYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFP-EMATYLRYVRRLDFFEK 298
Query: 303 PDYDYLRKLFTDLFDRSGFVFDYEYDWAGKPLPTPIGTVHTD--LPSQ---PQLRDKTQP 357
PDYDYLRKLFTDLFDR G++FDYEYDW GK LPTP+G V D L S Q RDK Q
Sbjct: 299 PDYDYLRKLFTDLFDRKGYMFDYEYDWIGKQLPTPVGAVQQDPALSSNREAHQHRDKMQ- 357
Query: 358 HSKNQA--------------------------------LNSTNGELNADDPTAGHSNAPI 385
SKNQ+ ++STNGELN DDPTAG SNAPI
Sbjct: 358 QSKNQSADHRAAWDSQQANPHHLRAHLAADRHGGSVQVVSSTNGELNTDDPTAGRSNAPI 417
Query: 386 TAPAEVEVADETKCCCFFKRRKRKSLQRHK 415
TAP EVEV DETKCCCFFKRRKRK++QRHK
Sbjct: 418 TAPTEVEVMDETKCCCFFKRRKRKTIQRHK 447
>gi|98986450 casein kinase 1, gamma 1 [Homo sapiens]
Length = 422
Score = 685 bits (1768), Expect = 0.0
Identities = 333/416 (80%), Positives = 364/416 (87%), Gaps = 11/416 (2%)
Query: 11 ETEEGRRMSKAGGGRSSHGIRSSGTSS--GVLMVGPNFRVGKKIGCGNFGELRLGKNLYT 68
E +E +R +K RS+H R SG+SS GVLMVGPNFRVGKKIGCGNFGELRLGKNLYT
Sbjct: 7 EKDERQRTTKPMAQRSAHCSRPSGSSSSSGVLMVGPNFRVGKKIGCGNFGELRLGKNLYT 66
Query: 69 NEYVAIKLEPIKSRAPQLHLEYRFYKQL-SATEGVPQVYYFGPCGKYNAMVLELLGPSLE 127
NEYVAIKLEPIKSRAPQLHLEYRFYKQL SA EG+PQVYYFGPCGKYNAMVLELLGPSLE
Sbjct: 67 NEYVAIKLEPIKSRAPQLHLEYRFYKQLGSAGEGLPQVYYFGPCGKYNAMVLELLGPSLE 126
Query: 128 DLFDLCDRTFTLKTVLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGRPGTKRQHAIHII 187
DLFDLCDRTFTLKTVLMIAIQL++RMEYVH+K+LIYRDVKPENFL+GR G K++H IHII
Sbjct: 127 DLFDLCDRTFTLKTVLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKEHVIHII 186
Query: 188 DFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLR 247
DFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLR
Sbjct: 187 DFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLR 246
Query: 248 GSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEEMATYLRYVRRLDFFEKPDYDY 307
GSLPWQGLKADTLKERYQKIGDTKR TPIE LCENFPEEMATYLRYVRRLDFFEKPDY+Y
Sbjct: 247 GSLPWQGLKADTLKERYQKIGDTKRNTPIEALCENFPEEMATYLRYVRRLDFFEKPDYEY 306
Query: 308 LRKLFTDLFDRSGFVFDYEYDWAGKPLPTPIGTVHTDLPSQPQLRD--------KTQPHS 359
LR LFTDLF++ G+ FDY YDW G+P+PTP+G+VH D + R+ Q
Sbjct: 307 LRTLFTDLFEKKGYTFDYAYDWVGRPIPTPVGSVHVDSGASAITRESHTHRDRPSQQQPL 366
Query: 360 KNQALNSTNGELNADDPTAGHSNAPITAPAEVEVADETKCCCFFKRRKRKSLQRHK 415
+NQ ++STNGELN DDPT HSNAPITA AEVEV +E KCCCFFKR+++K+ QRHK
Sbjct: 367 RNQVVSSTNGELNVDDPTGAHSNAPITAHAEVEVVEEAKCCCFFKRKRKKTAQRHK 422
>gi|113462010 casein kinase 1, gamma 3 isoform 4 [Homo sapiens]
Length = 455
Score = 677 bits (1746), Expect = 0.0
Identities = 349/458 (76%), Positives = 375/458 (81%), Gaps = 51/458 (11%)
Query: 4 DKKGGKGETEEGRRMSKAGGGRSSHGIRSSGTSS-GVLMVGPNFRVGKKIGCGNFGELRL 62
+KK K ++++ RM++ G RS H R +G+SS GVLMVGPNFRVGKKIGCGNFGELRL
Sbjct: 3 NKKKDKDKSDD--RMARPSG-RSGHNTRGTGSSSSGVLMVGPNFRVGKKIGCGNFGELRL 59
Query: 63 GKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLSATEGVPQVYYFGPCGKYNAMVLELL 122
GKNLYTNEYVAIKLEP+KSRAPQLHLEYRFYKQL + +G+PQVYYFGPCGKYNAMVLELL
Sbjct: 60 GKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSGDGIPQVYYFGPCGKYNAMVLELL 119
Query: 123 GPSLEDLFDLCDRTFTLKTVLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGRPGTKRQH 182
GPSLEDLFDLCDRTF+LKTVLMIAIQLI+RMEYVH+K+LIYRDVKPENFL+GRPG K Q
Sbjct: 120 GPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNKTQQ 179
Query: 183 AIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMF 242
IHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMF
Sbjct: 180 VIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMF 239
Query: 243 MYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEEMATYLRYVRRLDFFEK 302
MYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFP EMATYLRYVRRLDFFEK
Sbjct: 240 MYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFP-EMATYLRYVRRLDFFEK 298
Query: 303 PDYDYLRKLFTDLFDRSGFVFDYEYDWAGKPLPTPIGTVHTD--LPSQ---PQLRDKTQP 357
PDYDYLRKLFTDLFDR G++FDYEYDW GK LPTP+G V D L S Q RDK Q
Sbjct: 299 PDYDYLRKLFTDLFDRKGYMFDYEYDWIGKQLPTPVGAVQQDPALSSNREAHQHRDKMQ- 357
Query: 358 HSKNQA--------------------------------LNSTNGELNADDPTAGHSNAPI 385
SKNQ+ ++STNGELN DDPTAG SNAPI
Sbjct: 358 QSKNQSADHRAAWDSQQANPHHLRAHLAADRHGGSVQVVSSTNGELNTDDPTAGRSNAPI 417
Query: 386 TAPAEVEVADETK--------CCCFFKRRKRKSLQRHK 415
TAP EVEV DET CCCFFKRRKRK++QRHK
Sbjct: 418 TAPTEVEVMDETNCQKVLNMWCCCFFKRRKRKTIQRHK 455
>gi|23199991 casein kinase 1 epsilon [Homo sapiens]
Length = 416
Score = 361 bits (926), Expect = e-100
Identities = 169/290 (58%), Positives = 227/290 (78%), Gaps = 2/290 (0%)
Query: 40 LMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLSAT 99
L VG +R+G+KIG G+FG++ LG N+ + E VAIKLE +K++ PQLH+E +FYK +
Sbjct: 3 LRVGNKYRLGRKIGSGSFGDIYLGANIASGEEVAIKLECVKTKHPQLHIESKFYKMMQGG 62
Query: 100 EGVPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLITRMEYVHTK 159
G+P + + G G YN MV+ELLGPSLEDLF+ C R F+LKTVL++A Q+I+R+EY+H+K
Sbjct: 63 VGIPSIKWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSK 122
Query: 160 SLIYRDVKPENFLVGRPGTKRQHAIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYM 219
+ I+RDVKP+NFL+G K+ + ++IIDFGLAK+Y D T +HIPYRE+K+LTGTARY
Sbjct: 123 NFIHRDVKPDNFLMGLG--KKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA 180
Query: 220 SINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVL 279
SINTHLG EQSRRDDLE+LG++ MYF GSLPWQGLKA T +++Y++I + K +TPIEVL
Sbjct: 181 SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL 240
Query: 280 CENFPEEMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRSGFVFDYEYDW 329
C+ +P E +TYL + R L F +KPDY YLR+LF +LF R GF +DY +DW
Sbjct: 241 CKGYPSEFSTYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDW 290
>gi|4503093 casein kinase 1 epsilon [Homo sapiens]
Length = 416
Score = 361 bits (926), Expect = e-100
Identities = 169/290 (58%), Positives = 227/290 (78%), Gaps = 2/290 (0%)
Query: 40 LMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLSAT 99
L VG +R+G+KIG G+FG++ LG N+ + E VAIKLE +K++ PQLH+E +FYK +
Sbjct: 3 LRVGNKYRLGRKIGSGSFGDIYLGANIASGEEVAIKLECVKTKHPQLHIESKFYKMMQGG 62
Query: 100 EGVPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLITRMEYVHTK 159
G+P + + G G YN MV+ELLGPSLEDLF+ C R F+LKTVL++A Q+I+R+EY+H+K
Sbjct: 63 VGIPSIKWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSK 122
Query: 160 SLIYRDVKPENFLVGRPGTKRQHAIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYM 219
+ I+RDVKP+NFL+G K+ + ++IIDFGLAK+Y D T +HIPYRE+K+LTGTARY
Sbjct: 123 NFIHRDVKPDNFLMGLG--KKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA 180
Query: 220 SINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVL 279
SINTHLG EQSRRDDLE+LG++ MYF GSLPWQGLKA T +++Y++I + K +TPIEVL
Sbjct: 181 SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL 240
Query: 280 CENFPEEMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRSGFVFDYEYDW 329
C+ +P E +TYL + R L F +KPDY YLR+LF +LF R GF +DY +DW
Sbjct: 241 CKGYPSEFSTYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDW 290
>gi|20544145 casein kinase 1, delta isoform 2 [Homo sapiens]
Length = 409
Score = 359 bits (922), Expect = 2e-99
Identities = 184/380 (48%), Positives = 257/380 (67%), Gaps = 11/380 (2%)
Query: 40 LMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLSAT 99
L VG +R+G+KIG G+FG++ LG ++ E VAIKLE +K++ PQLH+E + YK +
Sbjct: 3 LRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGG 62
Query: 100 EGVPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLITRMEYVHTK 159
G+P + + G G YN MV+ELLGPSLEDLF+ C R F+LKTVL++A Q+I+R+EY+H+K
Sbjct: 63 VGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSK 122
Query: 160 SLIYRDVKPENFLVGRPGTKRQHAIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYM 219
+ I+RDVKP+NFL+G K+ + ++IIDFGLAK+Y D T +HIPYRE+K+LTGTARY
Sbjct: 123 NFIHRDVKPDNFLMGLG--KKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA 180
Query: 220 SINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVL 279
SINTHLG EQSRRDDLE+LG++ MYF GSLPWQGLKA T +++Y++I + K +TPIEVL
Sbjct: 181 SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL 240
Query: 280 CENFPEEMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRSGFVFDYEYDWAGKPLPTPIG 339
C+ +P E ATYL + R L F +KPDY YLR+LF +LF R GF +DY +DW L
Sbjct: 241 CKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDW--NMLKFGAS 298
Query: 340 TVHTDLPSQPQLRDKTQPHSKNQAL----NSTNGELNADDPTAGHSNAPITAPAEVEVAD 395
D + + R++ HS+N A ++ +G L A P+T P
Sbjct: 299 RAADDAERERRDREERLRHSRNPATRGLPSTASGRLRGTQEVA--PPTPLT-PTSHTANT 355
Query: 396 ETKCCCFFKRRKRKSLQRHK 415
+ +R ++ S++ H+
Sbjct: 356 SPRPVSGMERERKVSMRLHR 375
>gi|20149530 casein kinase 1, delta isoform 1 [Homo sapiens]
Length = 415
Score = 359 bits (922), Expect = 2e-99
Identities = 184/380 (48%), Positives = 257/380 (67%), Gaps = 11/380 (2%)
Query: 40 LMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLSAT 99
L VG +R+G+KIG G+FG++ LG ++ E VAIKLE +K++ PQLH+E + YK +
Sbjct: 3 LRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGG 62
Query: 100 EGVPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLITRMEYVHTK 159
G+P + + G G YN MV+ELLGPSLEDLF+ C R F+LKTVL++A Q+I+R+EY+H+K
Sbjct: 63 VGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSK 122
Query: 160 SLIYRDVKPENFLVGRPGTKRQHAIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYM 219
+ I+RDVKP+NFL+G K+ + ++IIDFGLAK+Y D T +HIPYRE+K+LTGTARY
Sbjct: 123 NFIHRDVKPDNFLMGLG--KKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA 180
Query: 220 SINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVL 279
SINTHLG EQSRRDDLE+LG++ MYF GSLPWQGLKA T +++Y++I + K +TPIEVL
Sbjct: 181 SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL 240
Query: 280 CENFPEEMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRSGFVFDYEYDWAGKPLPTPIG 339
C+ +P E ATYL + R L F +KPDY YLR+LF +LF R GF +DY +DW L
Sbjct: 241 CKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDW--NMLKFGAS 298
Query: 340 TVHTDLPSQPQLRDKTQPHSKNQAL----NSTNGELNADDPTAGHSNAPITAPAEVEVAD 395
D + + R++ HS+N A ++ +G L A P+T P
Sbjct: 299 RAADDAERERRDREERLRHSRNPATRGLPSTASGRLRGTQEVA--PPTPLT-PTSHTANT 355
Query: 396 ETKCCCFFKRRKRKSLQRHK 415
+ +R ++ S++ H+
Sbjct: 356 SPRPVSGMERERKVSMRLHR 375
>gi|68303572 casein kinase 1, alpha 1 isoform 2 [Homo sapiens]
Length = 337
Score = 329 bits (843), Expect = 3e-90
Identities = 162/298 (54%), Positives = 214/298 (71%), Gaps = 2/298 (0%)
Query: 32 SSGTSSGVLMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYR 91
SS S +VG +++ +KIG G+FG++ L N+ E VA+KLE K+R PQL E +
Sbjct: 3 SSSGSKAEFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESK 62
Query: 92 FYKQLSATEGVPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLIT 151
YK L G+P + ++G YN +V++LLGPSLEDLF+ C R FT+KTVLM+A Q+I+
Sbjct: 63 LYKILQGGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMIS 122
Query: 152 RMEYVHTKSLIYRDVKPENFLVGRPGTKRQHAIHIIDFGLAKEYIDPETKKHIPYREHKS 211
R+EYVHTK+ I+RD+KP+NFL+G + + + +IDFGLAK+Y D T++HIPYRE K+
Sbjct: 123 RIEYVHTKNFIHRDIKPDNFLMGIG--RHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKN 180
Query: 212 LTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTK 271
LTGTARY SIN HLG EQSRRDD+E+LG++ MYF R SLPWQGLKA T K++Y+KI + K
Sbjct: 181 LTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKK 240
Query: 272 RATPIEVLCENFPEEMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRSGFVFDYEYDW 329
+TP+EVLC+ FP E A YL Y R L F E PDY YLR+LF LF +DY +DW
Sbjct: 241 MSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDW 298
>gi|68303575 casein kinase 1, alpha 1 isoform 1 [Homo sapiens]
Length = 365
Score = 323 bits (827), Expect = 2e-88
Identities = 165/324 (50%), Positives = 217/324 (66%), Gaps = 26/324 (8%)
Query: 32 SSGTSSGVLMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYR 91
SS S +VG +++ +KIG G+FG++ L N+ E VA+KLE K+R PQL E +
Sbjct: 3 SSSGSKAEFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESK 62
Query: 92 FYKQLSATEGVPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLIT 151
YK L G+P + ++G YN +V++LLGPSLEDLF+ C R FT+KTVLM+A Q+I+
Sbjct: 63 LYKILQGGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMIS 122
Query: 152 RMEYVHTKSLIYRDVKPENFLVG----------RPGTKRQHA----------------IH 185
R+EYVHTK+ I+RD+KP+NFL+G P KR+ + +
Sbjct: 123 RIEYVHTKNFIHRDIKPDNFLMGIGRHCNKCLESPVGKRKRSMTVSTSQDPSFSGLNQLF 182
Query: 186 IIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYF 245
+IDFGLAK+Y D T++HIPYRE K+LTGTARY SIN HLG EQSRRDD+E+LG++ MYF
Sbjct: 183 LIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYF 242
Query: 246 LRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEEMATYLRYVRRLDFFEKPDY 305
R SLPWQGLKA T K++Y+KI + K +TP+EVLC+ FP E A YL Y R L F E PDY
Sbjct: 243 NRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDY 302
Query: 306 DYLRKLFTDLFDRSGFVFDYEYDW 329
YLR+LF LF +DY +DW
Sbjct: 303 MYLRQLFRILFRTLNHQYDYTFDW 326
>gi|21624639 casein kinase 1, alpha 1-like [Homo sapiens]
Length = 337
Score = 316 bits (810), Expect = 2e-86
Identities = 156/294 (53%), Positives = 208/294 (70%), Gaps = 2/294 (0%)
Query: 36 SSGVLMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQ 95
S L+VG +++ +KIG G+FG++ LG E VA+KLE K + PQL E + Y
Sbjct: 7 SKAELVVGGKYKLVRKIGSGSFGDVYLGITTTNGEEVAVKLESQKVKHPQLLYESKLYTI 66
Query: 96 LSATEGVPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLITRMEY 155
L G+P ++++G N +V++LLGPSLEDLF+ C R FT+KTVLM+A Q+I+R+EY
Sbjct: 67 LQGGVGIPHMHWYGQEKDNNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEY 126
Query: 156 VHTKSLIYRDVKPENFLVGRPGTKRQHAIHIIDFGLAKEYIDPETKKHIPYREHKSLTGT 215
VHTK+ ++RD+KP+NFL+G + + + +IDFGLAK+Y D T++HIPYRE K L GT
Sbjct: 127 VHTKNFLHRDIKPDNFLMGTG--RHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKHLIGT 184
Query: 216 ARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATP 275
RY SIN HLG EQSRRDD+E+LG++FMYF R SLPWQGLKA T K++Y+KI + K +TP
Sbjct: 185 VRYASINAHLGIEQSRRDDMESLGYVFMYFNRTSLPWQGLKAMTKKQKYEKISEKKMSTP 244
Query: 276 IEVLCENFPEEMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRSGFVFDYEYDW 329
+EVLC+ FP E A YL Y R L F E PDY YLR+LF LF +DY +DW
Sbjct: 245 VEVLCKGFPAEFAMYLNYCRGLRFEEVPDYMYLRQLFRILFRTLNHQYDYTFDW 298
>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
Length = 1321
Score = 160 bits (406), Expect = 2e-39
Identities = 101/310 (32%), Positives = 159/310 (51%), Gaps = 11/310 (3%)
Query: 41 MVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLSATE 100
+V ++V KKIG G FGE+ +L T E VA+K+E + L +E K+L +
Sbjct: 29 VVKDRWKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKD 88
Query: 101 GVPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDR-TFTLKTVLMIAIQLITRMEYVHTK 159
V + G K+N +V++L G +L DL R TFTL T L + Q++ +E +H+
Sbjct: 89 HVCRFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFTLSTTLRLGKQILESIEAIHSV 148
Query: 160 SLIYRDVKPENFLVGR-PGTKRQHAIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARY 218
++RD+KP NF +GR P T R+ +++DFGLA++Y + T P R GT RY
Sbjct: 149 GFLHRDIKPSNFAMGRLPSTYRK--CYMLDFGLARQYTN-TTGDVRPPRNVAGFRGTVRY 205
Query: 219 MSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEV 278
S+N H +E R DDL +L +M + F G LPW+ +K +++G K +
Sbjct: 206 ASVNAHKNREMGRHDDLWSLFYMLVEFAVGQLPWRKIKDK------EQVGMIKEKYEHRM 259
Query: 279 LCENFPEEMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRSGFVFDYEYDWAGKPLPTPI 338
L ++ P E +L ++ LD+F KPDY + +F + G + +DW +
Sbjct: 260 LLKHMPSEFHLFLDHIASLDYFTKPDYQLIMSVFENSMKERGIAENEAFDWEKAGTDALL 319
Query: 339 GTVHTDLPSQ 348
T + P Q
Sbjct: 320 STSTSTPPQQ 329
>gi|116812624 tau tubulin kinase 2 [Homo sapiens]
Length = 1244
Score = 157 bits (397), Expect = 2e-38
Identities = 99/320 (30%), Positives = 165/320 (51%), Gaps = 13/320 (4%)
Query: 40 LMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLSAT 99
++V ++V +KIG G FGE+ ++ T E VA+K+E + L +E K+L
Sbjct: 15 ILVKERWKVLRKIGGGGFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQGK 74
Query: 100 EGVPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDR-TFTLKTVLMIAIQLITRMEYVHT 158
+ V + G ++N +V++L G +L DL R TFT+ T L + Q++ +E +H+
Sbjct: 75 DHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHS 134
Query: 159 KSLIYRDVKPENFLVGR-PGTKRQHAIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTAR 217
++RD+KP NF +GR P T R+ +++DFGLA+++ + P R GT R
Sbjct: 135 VGFLHRDIKPSNFAMGRFPSTCRK--CYMLDFGLARQFTNSCGDVRPP-RAVAGFRGTVR 191
Query: 218 YMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIE 277
Y SIN H +E R DDL +L +M + F+ G LPW+ +K +++G K
Sbjct: 192 YASINAHRNREMGRHDDLWSLFYMLVEFVVGQLPWRKIKDK------EQVGSIKERYDHR 245
Query: 278 VLCENFPEEMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRSGFVFDYEYDWAGKPLPTP 337
++ ++ P E + +L ++ LD+F KPDY L +F + G + +DW
Sbjct: 246 LMLKHLPPEFSIFLDHISSLDYFTKPDYQLLTSVFDNSIKTFGVIESDPFDWEKTGNDGS 305
Query: 338 IGTVHTDLPSQPQLRDKTQP 357
+ T T + PQL + P
Sbjct: 306 LTTTTTS--TTPQLHTRLTP 323
>gi|4507903 vaccinia related kinase 1 [Homo sapiens]
Length = 396
Score = 120 bits (302), Expect = 2e-27
Identities = 90/326 (27%), Positives = 150/326 (46%), Gaps = 36/326 (11%)
Query: 17 RMSKAGGGRSSHGIRSSGTSSGVL-----MVGPNFRVGKKIGCGNFG-----ELRLGKNL 66
R+ A GR S R V M ++VG IG G FG ++ +++
Sbjct: 3 RVKAAQAGRQSSAKRHLAEQFAVGEIITDMAKKEWKVGLPIGQGGFGCIYLADMNSSESV 62
Query: 67 YTNEYVAIKLEPIKSRAPQLHLEYRFYKQLSATE--------------GVPQVYYFGPCG 112
++ +K+EP S L E +FY++ + E GVP+ + G
Sbjct: 63 GSDAPCVVKVEP--SDNGPLFTELKFYQRAAKPEQIQKWIRTRKLKYLGVPKYWGSGLHD 120
Query: 113 K----YNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLITRMEYVHTKSLIYRDVKP 168
K Y M+++ G L+ +++ + F+ KTVL ++++++ +EY+H ++ D+K
Sbjct: 121 KNGKSYRFMIMDRFGSDLQKIYEANAKRFSRKTVLQLSLRILDILEYIHEHEYVHGDIKA 180
Query: 169 ENFLVGRPGTKRQHAIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKE 228
N L+ K ++++D+GLA Y K + GT + SI+ H G
Sbjct: 181 SNLLLNY---KNPDQVYLVDYGLAYRYCPEGVHKEYKEDPKRCHDGTIEFTSIDAHNGVA 237
Query: 229 QSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLC---ENFPE 285
SRR DLE LG+ + +L G LPW+ D R KI + + C +N P
Sbjct: 238 PSRRGDLEILGYCMIQWLTGHLPWEDNLKDPKYVRDSKIRYRENIASLMDKCFPEKNKPG 297
Query: 286 EMATYLRYVRRLDFFEKPDYDYLRKL 311
E+A Y+ V+ LD+ EKP Y+ LR +
Sbjct: 298 EIAKYMETVKLLDYTEKPLYENLRDI 323
>gi|194440713 vaccinia related kinase 2 isoform 3 [Homo sapiens]
Length = 396
Score = 100 bits (248), Expect = 3e-21
Identities = 87/302 (28%), Positives = 134/302 (44%), Gaps = 44/302 (14%)
Query: 41 MVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVA---IKLEPIKSRAPQLHLEYRFYKQLS 97
M G + +GKKIG G FG + L E A +K+E + P L E +FY++++
Sbjct: 24 MEGNQWVLGKKIGSGGFGLIYLAFPTNKPEKDARHVVKVE-YQENGP-LFSELKFYQRVA 81
Query: 98 ATE--------------GVPQVYYFGPCG----KYNAMVLELLGPSLEDLFDLCDRTFTL 139
+ G+P Y G Y MV+E LG L+ + + TF
Sbjct: 82 KKDCIKKWIERKQLDYLGIPLFYGSGLTEFKGRSYRFMVMERLGIDLQKISGQ-NGTFKK 140
Query: 140 KTVLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGRPGTKRQHAIHIIDFGLAKEYIDPE 199
TVL + I+++ +EY+H ++ D+K N L+G K +++ D+GL+ Y
Sbjct: 141 STVLQLGIRMLDVLEYIHENEYVHGDIKAANLLLGY---KNPDQVYLADYGLSYRYCPNG 197
Query: 200 TKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPW------- 252
K K GT + S++ H G SRR D+E LG+ + +L G LPW
Sbjct: 198 NHKQYQENPRKGHNGTIEFTSLDAHKGVALSRRSDVEILGYCMLRWLCGKLPWEQNLKDP 257
Query: 253 ---QGLKADTLKERYQKIGDTKRATPIEVLCENFPEEMATYLRYVRRLDFFEKPDYDYLR 309
Q K + L E Q + K A C E+A +L L + EKP+Y L+
Sbjct: 258 VAVQTAKTNLLDELPQSV--LKWAPSGSSCC-----EIAQFLVCAHSLAYDEKPNYQALK 310
Query: 310 KL 311
K+
Sbjct: 311 KI 312
>gi|194440711 vaccinia related kinase 2 isoform 2 [Homo sapiens]
Length = 485
Score = 100 bits (248), Expect = 3e-21
Identities = 87/302 (28%), Positives = 134/302 (44%), Gaps = 44/302 (14%)
Query: 41 MVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVA---IKLEPIKSRAPQLHLEYRFYKQLS 97
M G + +GKKIG G FG + L E A +K+E + P L E +FY++++
Sbjct: 1 MEGNQWVLGKKIGSGGFGLIYLAFPTNKPEKDARHVVKVE-YQENGP-LFSELKFYQRVA 58
Query: 98 ATE--------------GVPQVYYFGPCG----KYNAMVLELLGPSLEDLFDLCDRTFTL 139
+ G+P Y G Y MV+E LG L+ + + TF
Sbjct: 59 KKDCIKKWIERKQLDYLGIPLFYGSGLTEFKGRSYRFMVMERLGIDLQKISGQ-NGTFKK 117
Query: 140 KTVLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGRPGTKRQHAIHIIDFGLAKEYIDPE 199
TVL + I+++ +EY+H ++ D+K N L+G K +++ D+GL+ Y
Sbjct: 118 STVLQLGIRMLDVLEYIHENEYVHGDIKAANLLLGY---KNPDQVYLADYGLSYRYCPNG 174
Query: 200 TKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPW------- 252
K K GT + S++ H G SRR D+E LG+ + +L G LPW
Sbjct: 175 NHKQYQENPRKGHNGTIEFTSLDAHKGVALSRRSDVEILGYCMLRWLCGKLPWEQNLKDP 234
Query: 253 ---QGLKADTLKERYQKIGDTKRATPIEVLCENFPEEMATYLRYVRRLDFFEKPDYDYLR 309
Q K + L E Q + K A C E+A +L L + EKP+Y L+
Sbjct: 235 VAVQTAKTNLLDELPQSV--LKWAPSGSSCC-----EIAQFLVCAHSLAYDEKPNYQALK 287
Query: 310 KL 311
K+
Sbjct: 288 KI 289
>gi|194440709 vaccinia related kinase 2 isoform 1 [Homo sapiens]
Length = 508
Score = 100 bits (248), Expect = 3e-21
Identities = 87/302 (28%), Positives = 134/302 (44%), Gaps = 44/302 (14%)
Query: 41 MVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVA---IKLEPIKSRAPQLHLEYRFYKQLS 97
M G + +GKKIG G FG + L E A +K+E + P L E +FY++++
Sbjct: 24 MEGNQWVLGKKIGSGGFGLIYLAFPTNKPEKDARHVVKVE-YQENGP-LFSELKFYQRVA 81
Query: 98 ATE--------------GVPQVYYFGPCG----KYNAMVLELLGPSLEDLFDLCDRTFTL 139
+ G+P Y G Y MV+E LG L+ + + TF
Sbjct: 82 KKDCIKKWIERKQLDYLGIPLFYGSGLTEFKGRSYRFMVMERLGIDLQKISGQ-NGTFKK 140
Query: 140 KTVLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGRPGTKRQHAIHIIDFGLAKEYIDPE 199
TVL + I+++ +EY+H ++ D+K N L+G K +++ D+GL+ Y
Sbjct: 141 STVLQLGIRMLDVLEYIHENEYVHGDIKAANLLLGY---KNPDQVYLADYGLSYRYCPNG 197
Query: 200 TKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPW------- 252
K K GT + S++ H G SRR D+E LG+ + +L G LPW
Sbjct: 198 NHKQYQENPRKGHNGTIEFTSLDAHKGVALSRRSDVEILGYCMLRWLCGKLPWEQNLKDP 257
Query: 253 ---QGLKADTLKERYQKIGDTKRATPIEVLCENFPEEMATYLRYVRRLDFFEKPDYDYLR 309
Q K + L E Q + K A C E+A +L L + EKP+Y L+
Sbjct: 258 VAVQTAKTNLLDELPQSV--LKWAPSGSSCC-----EIAQFLVCAHSLAYDEKPNYQALK 310
Query: 310 KL 311
K+
Sbjct: 311 KI 312
>gi|194440707 vaccinia related kinase 2 isoform 1 [Homo sapiens]
Length = 508
Score = 100 bits (248), Expect = 3e-21
Identities = 87/302 (28%), Positives = 134/302 (44%), Gaps = 44/302 (14%)
Query: 41 MVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVA---IKLEPIKSRAPQLHLEYRFYKQLS 97
M G + +GKKIG G FG + L E A +K+E + P L E +FY++++
Sbjct: 24 MEGNQWVLGKKIGSGGFGLIYLAFPTNKPEKDARHVVKVE-YQENGP-LFSELKFYQRVA 81
Query: 98 ATE--------------GVPQVYYFGPCG----KYNAMVLELLGPSLEDLFDLCDRTFTL 139
+ G+P Y G Y MV+E LG L+ + + TF
Sbjct: 82 KKDCIKKWIERKQLDYLGIPLFYGSGLTEFKGRSYRFMVMERLGIDLQKISGQ-NGTFKK 140
Query: 140 KTVLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGRPGTKRQHAIHIIDFGLAKEYIDPE 199
TVL + I+++ +EY+H ++ D+K N L+G K +++ D+GL+ Y
Sbjct: 141 STVLQLGIRMLDVLEYIHENEYVHGDIKAANLLLGY---KNPDQVYLADYGLSYRYCPNG 197
Query: 200 TKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPW------- 252
K K GT + S++ H G SRR D+E LG+ + +L G LPW
Sbjct: 198 NHKQYQENPRKGHNGTIEFTSLDAHKGVALSRRSDVEILGYCMLRWLCGKLPWEQNLKDP 257
Query: 253 ---QGLKADTLKERYQKIGDTKRATPIEVLCENFPEEMATYLRYVRRLDFFEKPDYDYLR 309
Q K + L E Q + K A C E+A +L L + EKP+Y L+
Sbjct: 258 VAVQTAKTNLLDELPQSV--LKWAPSGSSCC-----EIAQFLVCAHSLAYDEKPNYQALK 310
Query: 310 KL 311
K+
Sbjct: 311 KI 312
>gi|71164884 vaccinia related kinase 2 isoform 1 [Homo sapiens]
Length = 508
Score = 100 bits (248), Expect = 3e-21
Identities = 87/302 (28%), Positives = 134/302 (44%), Gaps = 44/302 (14%)
Query: 41 MVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVA---IKLEPIKSRAPQLHLEYRFYKQLS 97
M G + +GKKIG G FG + L E A +K+E + P L E +FY++++
Sbjct: 24 MEGNQWVLGKKIGSGGFGLIYLAFPTNKPEKDARHVVKVE-YQENGP-LFSELKFYQRVA 81
Query: 98 ATE--------------GVPQVYYFGPCG----KYNAMVLELLGPSLEDLFDLCDRTFTL 139
+ G+P Y G Y MV+E LG L+ + + TF
Sbjct: 82 KKDCIKKWIERKQLDYLGIPLFYGSGLTEFKGRSYRFMVMERLGIDLQKISGQ-NGTFKK 140
Query: 140 KTVLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGRPGTKRQHAIHIIDFGLAKEYIDPE 199
TVL + I+++ +EY+H ++ D+K N L+G K +++ D+GL+ Y
Sbjct: 141 STVLQLGIRMLDVLEYIHENEYVHGDIKAANLLLGY---KNPDQVYLADYGLSYRYCPNG 197
Query: 200 TKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPW------- 252
K K GT + S++ H G SRR D+E LG+ + +L G LPW
Sbjct: 198 NHKQYQENPRKGHNGTIEFTSLDAHKGVALSRRSDVEILGYCMLRWLCGKLPWEQNLKDP 257
Query: 253 ---QGLKADTLKERYQKIGDTKRATPIEVLCENFPEEMATYLRYVRRLDFFEKPDYDYLR 309
Q K + L E Q + K A C E+A +L L + EKP+Y L+
Sbjct: 258 VAVQTAKTNLLDELPQSV--LKWAPSGSSCC-----EIAQFLVCAHSLAYDEKPNYQALK 310
Query: 310 KL 311
K+
Sbjct: 311 KI 312
>gi|209862855 vaccinia related kinase 2 isoform 6 [Homo sapiens]
Length = 390
Score = 88.6 bits (218), Expect = 1e-17
Identities = 62/205 (30%), Positives = 96/205 (46%), Gaps = 21/205 (10%)
Query: 117 MVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGRP 176
MV+E LG L+ + + TF TVL + I+++ +EY+H ++ D+K N L+G
Sbjct: 1 MVMERLGIDLQKISGQ-NGTFKKSTVLQLGIRMLDVLEYIHENEYVHGDIKAANLLLGY- 58
Query: 177 GTKRQHAIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLE 236
K +++ D+GL+ Y K K GT + S++ H G SRR D+E
Sbjct: 59 --KNPDQVYLADYGLSYRYCPNGNHKQYQENPRKGHNGTIEFTSLDAHKGVALSRRSDVE 116
Query: 237 ALGHMFMYFLRGSLPW----------QGLKADTLKERYQKIGDTKRATPIEVLCENFPEE 286
LG+ + +L G LPW Q K + L E Q + K A C E
Sbjct: 117 ILGYCMLRWLCGKLPWEQNLKDPVAVQTAKTNLLDELPQSV--LKWAPSGSSCC-----E 169
Query: 287 MATYLRYVRRLDFFEKPDYDYLRKL 311
+A +L L + EKP+Y L+K+
Sbjct: 170 IAQFLVCAHSLAYDEKPNYQALKKI 194
>gi|71164888 vaccinia related kinase 3 isoform 2 [Homo sapiens]
Length = 424
Score = 82.8 bits (203), Expect = 5e-16
Identities = 66/231 (28%), Positives = 109/231 (47%), Gaps = 14/231 (6%)
Query: 88 LEYRFYKQLSATE--GVPQVYYFGPC-GKYNAMVLELLGPSLEDLFDLCDR-TFTLKTVL 143
L+ +K+L +T +P FG KY +VL LG SL+ D+ + + ++VL
Sbjct: 175 LQVNKWKKLYSTPLLAIPTCMGFGVHQDKYRFLVLPSLGRSLQSALDVSPKHVLSERSVL 234
Query: 144 MIAIQLITRMEYVHTKSLIYRDVKPENFLVGRPGTKRQHAIHIIDFGLAKEYIDPETKKH 203
+A +L+ +E++H ++ +V EN V + Q + + +G A Y + KH
Sbjct: 235 QVACRLLDALEFLHENEYVHGNVTAENIFVD---PEDQSQVTLAGYGFAFRYCP--SGKH 289
Query: 204 IPYRE--HKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLK 261
+ Y E G ++S++ H G SRR DL++LG+ + +L G LPW +T
Sbjct: 290 VAYVEGSRSPHEGDLEFISMDLHKGCGPSRRSDLQSLGYCMLKWLYGFLPWTNCLPNTED 349
Query: 262 ERYQKIGDTKRATPIEVLCENF---PEEMATYLRYVRRLDFFEKPDYDYLR 309
QK + P C ++ E + YL+ V L + EKP Y LR
Sbjct: 350 IMKQKQKFVDKPGPFVGPCGHWIRPSETLQKYLKVVMALTYEEKPPYAMLR 400
>gi|71164886 vaccinia related kinase 3 isoform 1 [Homo sapiens]
Length = 474
Score = 82.8 bits (203), Expect = 5e-16
Identities = 66/231 (28%), Positives = 109/231 (47%), Gaps = 14/231 (6%)
Query: 88 LEYRFYKQLSATE--GVPQVYYFGPC-GKYNAMVLELLGPSLEDLFDLCDR-TFTLKTVL 143
L+ +K+L +T +P FG KY +VL LG SL+ D+ + + ++VL
Sbjct: 225 LQVNKWKKLYSTPLLAIPTCMGFGVHQDKYRFLVLPSLGRSLQSALDVSPKHVLSERSVL 284
Query: 144 MIAIQLITRMEYVHTKSLIYRDVKPENFLVGRPGTKRQHAIHIIDFGLAKEYIDPETKKH 203
+A +L+ +E++H ++ +V EN V + Q + + +G A Y + KH
Sbjct: 285 QVACRLLDALEFLHENEYVHGNVTAENIFVD---PEDQSQVTLAGYGFAFRYCP--SGKH 339
Query: 204 IPYRE--HKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLK 261
+ Y E G ++S++ H G SRR DL++LG+ + +L G LPW +T
Sbjct: 340 VAYVEGSRSPHEGDLEFISMDLHKGCGPSRRSDLQSLGYCMLKWLYGFLPWTNCLPNTED 399
Query: 262 ERYQKIGDTKRATPIEVLCENF---PEEMATYLRYVRRLDFFEKPDYDYLR 309
QK + P C ++ E + YL+ V L + EKP Y LR
Sbjct: 400 IMKQKQKFVDKPGPFVGPCGHWIRPSETLQKYLKVVMALTYEEKPPYAMLR 450
>gi|239756427 PREDICTED: similar to 3-phosphoinositide dependent
protein kinase-1 [Homo sapiens]
Length = 471
Score = 73.2 bits (178), Expect = 4e-13
Identities = 61/222 (27%), Positives = 101/222 (45%), Gaps = 32/222 (14%)
Query: 45 NFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEP-------------IKSRAPQLHLEYR 91
+F+ GK +G G+F + L + L T+ AIK+ + R L++
Sbjct: 100 DFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHP 159
Query: 92 FYKQLSATEGVPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLIT 151
F+ +L T + YFG N +L+ + + + C R +T ++++
Sbjct: 160 FFVKLYFTFQTTRRLYFGLSYAKNGELLKYIR-KIGSFDETCTRFYTA--------EIVS 210
Query: 152 RMEYVHTKSLIYRDVKPENFLVGRPGTKRQHAIHIIDFGLAKEYIDPETKKHIPYREHKS 211
+EY+H K +I+RD+KPEN L+ I I DFG AK + PE+K+ S
Sbjct: 211 ALEYLHGKGIIHRDLKPENILL-----NEDMHIQITDFGTAK-VLSPESKQ----ARANS 260
Query: 212 LTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQ 253
GTA+Y+S K + DL ALG + + G P++
Sbjct: 261 FVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFR 302
>gi|4505695 3-phosphoinositide dependent protein kinase-1 isoform 1
[Homo sapiens]
Length = 556
Score = 72.8 bits (177), Expect = 5e-13
Identities = 61/222 (27%), Positives = 101/222 (45%), Gaps = 32/222 (14%)
Query: 45 NFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEP-------------IKSRAPQLHLEYR 91
+F+ GK +G G+F + L + L T+ AIK+ + R L++
Sbjct: 81 DFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHP 140
Query: 92 FYKQLSATEGVPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLIT 151
F+ +L T + YFG N +L+ + + + C R +T ++++
Sbjct: 141 FFVKLYFTFQDDEKLYFGLSYAKNGELLKYIR-KIGSFDETCTRFYTA--------EIVS 191
Query: 152 RMEYVHTKSLIYRDVKPENFLVGRPGTKRQHAIHIIDFGLAKEYIDPETKKHIPYREHKS 211
+EY+H K +I+RD+KPEN L+ I I DFG AK + PE+K+ S
Sbjct: 192 ALEYLHGKGIIHRDLKPENILL-----NEDMHIQITDFGTAK-VLSPESKQ----ARANS 241
Query: 212 LTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQ 253
GTA+Y+S K + DL ALG + + G P++
Sbjct: 242 FVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFR 283
>gi|239745384 PREDICTED: hypothetical protein XP_002343452 [Homo
sapiens]
Length = 396
Score = 72.8 bits (177), Expect = 5e-13
Identities = 61/222 (27%), Positives = 101/222 (45%), Gaps = 32/222 (14%)
Query: 45 NFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEP-------------IKSRAPQLHLEYR 91
+F+ GK +G G+F + L + L T+ AIK+ + R L++
Sbjct: 54 DFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHP 113
Query: 92 FYKQLSATEGVPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLIT 151
F+ +L T + YFG N +L+ + + + C R +T ++++
Sbjct: 114 FFVKLYFTFQDDEKLYFGLSYAKNGELLKYIR-KIGSFDETCTRFYTA--------EIVS 164
Query: 152 RMEYVHTKSLIYRDVKPENFLVGRPGTKRQHAIHIIDFGLAKEYIDPETKKHIPYREHKS 211
+EY+H K +I+RD+KPEN L+ I I DFG AK + PE+K+ S
Sbjct: 165 ALEYLHGKGIIHRDLKPENILL-----NEDMHIQITDFGTAK-VLSPESKQ----ARANS 214
Query: 212 LTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQ 253
GTA+Y+S K + DL ALG + + G P++
Sbjct: 215 FVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFR 256
>gi|38327572 serine/threonine protein kinase 6 [Homo sapiens]
Length = 403
Score = 67.0 bits (162), Expect = 3e-11
Identities = 58/238 (24%), Positives = 105/238 (44%), Gaps = 27/238 (11%)
Query: 45 NFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLSATEGV-- 102
+F +G+ +G G FG + L + + +A+K+ K++ + +E++ +++ +
Sbjct: 132 DFEIGRPLGKGKFGNVYLAREKQSKFILALKVL-FKAQLEKAGVEHQLRREVEIQSHLRH 190
Query: 103 PQV-----YYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLITRMEYVH 157
P + Y+ Y + LG +L L F + +L + Y H
Sbjct: 191 PNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK--FDEQRTATYITELANALSYCH 248
Query: 158 TKSLIYRDVKPENFLVGRPGTKRQHAIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTAR 217
+K +I+RD+KPEN L+G G + I DFG + H P +L GT
Sbjct: 249 SKRVIHRDIKPENLLLGSAG-----ELKIADFGWS---------VHAPSSRRTTLCGTLD 294
Query: 218 YMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATP 275
Y+ G+ + DL +LG + FL G P++ A+T +E Y++I + P
Sbjct: 295 YLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFE---ANTYQETYKRISRVEFTFP 349
>gi|38327570 serine/threonine protein kinase 6 [Homo sapiens]
Length = 403
Score = 67.0 bits (162), Expect = 3e-11
Identities = 58/238 (24%), Positives = 105/238 (44%), Gaps = 27/238 (11%)
Query: 45 NFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLSATEGV-- 102
+F +G+ +G G FG + L + + +A+K+ K++ + +E++ +++ +
Sbjct: 132 DFEIGRPLGKGKFGNVYLAREKQSKFILALKVL-FKAQLEKAGVEHQLRREVEIQSHLRH 190
Query: 103 PQV-----YYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLITRMEYVH 157
P + Y+ Y + LG +L L F + +L + Y H
Sbjct: 191 PNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK--FDEQRTATYITELANALSYCH 248
Query: 158 TKSLIYRDVKPENFLVGRPGTKRQHAIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTAR 217
+K +I+RD+KPEN L+G G + I DFG + H P +L GT
Sbjct: 249 SKRVIHRDIKPENLLLGSAG-----ELKIADFGWS---------VHAPSSRRTTLCGTLD 294
Query: 218 YMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATP 275
Y+ G+ + DL +LG + FL G P++ A+T +E Y++I + P
Sbjct: 295 YLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFE---ANTYQETYKRISRVEFTFP 349
>gi|38327568 serine/threonine protein kinase 6 [Homo sapiens]
Length = 403
Score = 67.0 bits (162), Expect = 3e-11
Identities = 58/238 (24%), Positives = 105/238 (44%), Gaps = 27/238 (11%)
Query: 45 NFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLSATEGV-- 102
+F +G+ +G G FG + L + + +A+K+ K++ + +E++ +++ +
Sbjct: 132 DFEIGRPLGKGKFGNVYLAREKQSKFILALKVL-FKAQLEKAGVEHQLRREVEIQSHLRH 190
Query: 103 PQV-----YYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLITRMEYVH 157
P + Y+ Y + LG +L L F + +L + Y H
Sbjct: 191 PNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK--FDEQRTATYITELANALSYCH 248
Query: 158 TKSLIYRDVKPENFLVGRPGTKRQHAIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTAR 217
+K +I+RD+KPEN L+G G + I DFG + H P +L GT
Sbjct: 249 SKRVIHRDIKPENLLLGSAG-----ELKIADFGWS---------VHAPSSRRTTLCGTLD 294
Query: 218 YMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATP 275
Y+ G+ + DL +LG + FL G P++ A+T +E Y++I + P
Sbjct: 295 YLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFE---ANTYQETYKRISRVEFTFP 349
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.138 0.417
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,578,358
Number of Sequences: 37866
Number of extensions: 780486
Number of successful extensions: 3243
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 368
Number of HSP's successfully gapped in prelim test: 318
Number of HSP's that attempted gapping in prelim test: 2407
Number of HSP's gapped (non-prelim): 822
length of query: 415
length of database: 18,247,518
effective HSP length: 105
effective length of query: 310
effective length of database: 14,271,588
effective search space: 4424192280
effective search space used: 4424192280
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.