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Search of human proteins with 153252201
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|153252201 solute carrier family 39 (zinc transporter),
member 6 isoform 1 [Homo sapiens]
(755 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|153252201 solute carrier family 39 (zinc transporter), member... 1554 0.0
gi|153252214 solute carrier family 39 (zinc transporter), member... 882 0.0
gi|187936949 solute carrier family 39 (zinc transporter), member... 483 e-136
gi|55741750 solute carrier family 39 (zinc transporter), member ... 483 e-136
gi|205830424 solute carrier family 39 (zinc transporter), member... 221 3e-57
gi|190360568 solute carrier family 39 (zinc transporter), member... 221 3e-57
gi|190358541 solute carrier family 39 (zinc transporter), member... 220 3e-57
gi|205830426 solute carrier family 39 (zinc transporter), member... 202 9e-52
gi|223633939 solute carrier family 39 (zinc transporter), member... 156 8e-38
gi|223633937 solute carrier family 39 (zinc transporter), member... 156 8e-38
gi|206597541 solute carrier family 39 (metal ion transporter), m... 156 8e-38
gi|206597539 solute carrier family 39 (metal ion transporter), m... 156 8e-38
gi|24586665 solute carrier family 39 (zinc transporter), member ... 155 1e-37
gi|205830407 solute carrier family 39 (zinc transporter), member... 155 1e-37
gi|205830403 solute carrier family 39 (zinc transporter), member... 155 1e-37
gi|115430259 solute carrier family 39 (zinc transporter), member... 154 2e-37
gi|115430255 solute carrier family 39 (zinc transporter), member... 154 2e-37
gi|205830405 solute carrier family 39 (zinc transporter), member... 139 1e-32
gi|117553619 solute carrier family 39, member 7 [Homo sapiens] 95 2e-19
gi|117553608 solute carrier family 39, member 7 [Homo sapiens] 95 2e-19
gi|40255101 solute carrier family 39 (zinc transporter), member ... 81 4e-15
gi|190014617 solute carrier family 39 (zinc transporter), member... 80 5e-15
gi|68299795 chromodomain helicase DNA binding protein 1 [Homo sa... 56 1e-07
gi|40254928 solute carrier family 39 (zinc transporter), member ... 55 2e-07
gi|221316609 sperm-associated cation channel 1 [Homo sapiens] 54 7e-07
gi|148762982 hypothetical protein LOC387640 [Homo sapiens] 51 5e-06
gi|229577422 solute carrier family 39, member 11 isoform 1 [Homo... 50 1e-05
gi|229577418 solute carrier family 39, member 11 isoform 2 [Homo... 50 1e-05
gi|32698730 nuclear fragile X mental retardation protein interac... 48 3e-05
gi|4504489 histidine-rich glycoprotein precursor [Homo sapiens] 48 4e-05
>gi|153252201 solute carrier family 39 (zinc transporter), member 6
isoform 1 [Homo sapiens]
Length = 755
Score = 1554 bits (4024), Expect = 0.0
Identities = 755/755 (100%), Positives = 755/755 (100%)
Query: 1 MARKLSVILILTFALSVTNPLHELKAAAFPQTTEKISPNWESGINVDLAISTRQYHLQQL 60
MARKLSVILILTFALSVTNPLHELKAAAFPQTTEKISPNWESGINVDLAISTRQYHLQQL
Sbjct: 1 MARKLSVILILTFALSVTNPLHELKAAAFPQTTEKISPNWESGINVDLAISTRQYHLQQL 60
Query: 61 FYRYGENNSLSVEGFRKLLQNIGIDKIKRIHIHHDHDHHSDHEHHSDHERHSDHEHHSDH 120
FYRYGENNSLSVEGFRKLLQNIGIDKIKRIHIHHDHDHHSDHEHHSDHERHSDHEHHSDH
Sbjct: 61 FYRYGENNSLSVEGFRKLLQNIGIDKIKRIHIHHDHDHHSDHEHHSDHERHSDHEHHSDH 120
Query: 121 EHHSDHDHHSHHNHAASGKNKRKALCPDHDSDSSGKDPRNSQGKGAHRPEHASGRRNVKD 180
EHHSDHDHHSHHNHAASGKNKRKALCPDHDSDSSGKDPRNSQGKGAHRPEHASGRRNVKD
Sbjct: 121 EHHSDHDHHSHHNHAASGKNKRKALCPDHDSDSSGKDPRNSQGKGAHRPEHASGRRNVKD 180
Query: 181 SVSASEVTSTVYNTVSEGTHFLETIETPRPGKLFPKDVSSSTPPSVTSKSRVSRLAGRKT 240
SVSASEVTSTVYNTVSEGTHFLETIETPRPGKLFPKDVSSSTPPSVTSKSRVSRLAGRKT
Sbjct: 181 SVSASEVTSTVYNTVSEGTHFLETIETPRPGKLFPKDVSSSTPPSVTSKSRVSRLAGRKT 240
Query: 241 NESVSEPRKGFMYSRNTNENPQECFNASKLLTSHGMGIQVPLNATEFNYLCPAIINQIDA 300
NESVSEPRKGFMYSRNTNENPQECFNASKLLTSHGMGIQVPLNATEFNYLCPAIINQIDA
Sbjct: 241 NESVSEPRKGFMYSRNTNENPQECFNASKLLTSHGMGIQVPLNATEFNYLCPAIINQIDA 300
Query: 301 RSCLIHTSEKKAEIPPKTYSLQIAWVGGFIAISIISFLSLLGVILVPLMNRVFFKFLLSF 360
RSCLIHTSEKKAEIPPKTYSLQIAWVGGFIAISIISFLSLLGVILVPLMNRVFFKFLLSF
Sbjct: 301 RSCLIHTSEKKAEIPPKTYSLQIAWVGGFIAISIISFLSLLGVILVPLMNRVFFKFLLSF 360
Query: 361 LVALAVGTLSGDAFLHLLPHSHASHHHSHSHEEPAMEMKRGPLFSHLSSQNIEESAYFDS 420
LVALAVGTLSGDAFLHLLPHSHASHHHSHSHEEPAMEMKRGPLFSHLSSQNIEESAYFDS
Sbjct: 361 LVALAVGTLSGDAFLHLLPHSHASHHHSHSHEEPAMEMKRGPLFSHLSSQNIEESAYFDS 420
Query: 421 TWKGLTALGGLYFMFLVEHVLTLIKQFKDKKKKNQKKPENDDDVEIKKQLSKYESQLSTN 480
TWKGLTALGGLYFMFLVEHVLTLIKQFKDKKKKNQKKPENDDDVEIKKQLSKYESQLSTN
Sbjct: 421 TWKGLTALGGLYFMFLVEHVLTLIKQFKDKKKKNQKKPENDDDVEIKKQLSKYESQLSTN 480
Query: 481 EEKVDTDDRTEGYLRADSQEPSHFDSQQPAVLEEEEVMIAHAHPQEVYNEYVPRGCKNKC 540
EEKVDTDDRTEGYLRADSQEPSHFDSQQPAVLEEEEVMIAHAHPQEVYNEYVPRGCKNKC
Sbjct: 481 EEKVDTDDRTEGYLRADSQEPSHFDSQQPAVLEEEEVMIAHAHPQEVYNEYVPRGCKNKC 540
Query: 541 HSHFHDTLGQSDDLIHHHHDYHHILHHHHHQNHHPHSHSQRYSREELKDAGVATLAWMVI 600
HSHFHDTLGQSDDLIHHHHDYHHILHHHHHQNHHPHSHSQRYSREELKDAGVATLAWMVI
Sbjct: 541 HSHFHDTLGQSDDLIHHHHDYHHILHHHHHQNHHPHSHSQRYSREELKDAGVATLAWMVI 600
Query: 601 MGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAVFCHELPHELGDFAVLLKAGMTVKQAVLY 660
MGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAVFCHELPHELGDFAVLLKAGMTVKQAVLY
Sbjct: 601 MGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAVFCHELPHELGDFAVLLKAGMTVKQAVLY 660
Query: 661 NALSAMLAYLGMATGIFIGHYAENVSMWIFALTAGLFMYVALVDMVPEMLHNDASDHGCS 720
NALSAMLAYLGMATGIFIGHYAENVSMWIFALTAGLFMYVALVDMVPEMLHNDASDHGCS
Sbjct: 661 NALSAMLAYLGMATGIFIGHYAENVSMWIFALTAGLFMYVALVDMVPEMLHNDASDHGCS 720
Query: 721 RWGYFFLQNAGMLLGFGIMLLISIFEHKIVFRINF 755
RWGYFFLQNAGMLLGFGIMLLISIFEHKIVFRINF
Sbjct: 721 RWGYFFLQNAGMLLGFGIMLLISIFEHKIVFRINF 755
>gi|153252214 solute carrier family 39 (zinc transporter), member 6
isoform 2 [Homo sapiens]
Length = 433
Score = 882 bits (2280), Expect = 0.0
Identities = 431/431 (100%), Positives = 431/431 (100%)
Query: 276 MGIQVPLNATEFNYLCPAIINQIDARSCLIHTSEKKAEIPPKTYSLQIAWVGGFIAISII 335
MGIQVPLNATEFNYLCPAIINQIDARSCLIHTSEKKAEIPPKTYSLQIAWVGGFIAISII
Sbjct: 1 MGIQVPLNATEFNYLCPAIINQIDARSCLIHTSEKKAEIPPKTYSLQIAWVGGFIAISII 60
Query: 336 SFLSLLGVILVPLMNRVFFKFLLSFLVALAVGTLSGDAFLHLLPHSHASHHHSHSHEEPA 395
SFLSLLGVILVPLMNRVFFKFLLSFLVALAVGTLSGDAFLHLLPHSHASHHHSHSHEEPA
Sbjct: 61 SFLSLLGVILVPLMNRVFFKFLLSFLVALAVGTLSGDAFLHLLPHSHASHHHSHSHEEPA 120
Query: 396 MEMKRGPLFSHLSSQNIEESAYFDSTWKGLTALGGLYFMFLVEHVLTLIKQFKDKKKKNQ 455
MEMKRGPLFSHLSSQNIEESAYFDSTWKGLTALGGLYFMFLVEHVLTLIKQFKDKKKKNQ
Sbjct: 121 MEMKRGPLFSHLSSQNIEESAYFDSTWKGLTALGGLYFMFLVEHVLTLIKQFKDKKKKNQ 180
Query: 456 KKPENDDDVEIKKQLSKYESQLSTNEEKVDTDDRTEGYLRADSQEPSHFDSQQPAVLEEE 515
KKPENDDDVEIKKQLSKYESQLSTNEEKVDTDDRTEGYLRADSQEPSHFDSQQPAVLEEE
Sbjct: 181 KKPENDDDVEIKKQLSKYESQLSTNEEKVDTDDRTEGYLRADSQEPSHFDSQQPAVLEEE 240
Query: 516 EVMIAHAHPQEVYNEYVPRGCKNKCHSHFHDTLGQSDDLIHHHHDYHHILHHHHHQNHHP 575
EVMIAHAHPQEVYNEYVPRGCKNKCHSHFHDTLGQSDDLIHHHHDYHHILHHHHHQNHHP
Sbjct: 241 EVMIAHAHPQEVYNEYVPRGCKNKCHSHFHDTLGQSDDLIHHHHDYHHILHHHHHQNHHP 300
Query: 576 HSHSQRYSREELKDAGVATLAWMVIMGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAVFCH 635
HSHSQRYSREELKDAGVATLAWMVIMGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAVFCH
Sbjct: 301 HSHSQRYSREELKDAGVATLAWMVIMGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAVFCH 360
Query: 636 ELPHELGDFAVLLKAGMTVKQAVLYNALSAMLAYLGMATGIFIGHYAENVSMWIFALTAG 695
ELPHELGDFAVLLKAGMTVKQAVLYNALSAMLAYLGMATGIFIGHYAENVSMWIFALTAG
Sbjct: 361 ELPHELGDFAVLLKAGMTVKQAVLYNALSAMLAYLGMATGIFIGHYAENVSMWIFALTAG 420
Query: 696 LFMYVALVDMV 706
LFMYVALVDMV
Sbjct: 421 LFMYVALVDMV 431
Score = 37.7 bits (86), Expect = 0.040
Identities = 14/32 (43%), Positives = 18/32 (56%)
Query: 90 IHIHHDHDHHSDHEHHSDHERHSDHEHHSDHE 121
IH HHD+ H H HH +H HS + +S E
Sbjct: 280 IHHHHDYHHILHHHHHQNHHPHSHSQRYSREE 311
Score = 35.4 bits (80), Expect = 0.20
Identities = 19/51 (37%), Positives = 24/51 (47%), Gaps = 5/51 (9%)
Query: 96 HDHHSDHEHHSDHERHSDHE-HHSDHEHHSDHDHHSHHNHAASGKNKRKAL 145
H H D SD H H+ HH H HH H +HH H+ S + R+ L
Sbjct: 266 HSHFHDTLGQSDDLIHHHHDYHHILHHHH----HQNHHPHSHSQRYSREEL 312
Score = 32.0 bits (71), Expect = 2.2
Identities = 15/47 (31%), Positives = 19/47 (40%), Gaps = 10/47 (21%)
Query: 92 IHHDHDHHSDHEHHSDHERHSDHEHHSDHEHHSDHDHHSHHNHAASG 138
IHH HD+H HH HH +H HS +S +G
Sbjct: 280 IHHHHDYHHILHHH----------HHQNHHPHSHSQRYSREELKDAG 316
Score = 31.6 bits (70), Expect = 2.8
Identities = 17/44 (38%), Positives = 20/44 (45%), Gaps = 5/44 (11%)
Query: 89 RIHIH-HDHDHHSDHEHHSDHERHSDHEHHSDHEHHSDHDHHSH 131
+ H H HD SD H H+ H HH HH +H HSH
Sbjct: 264 KCHSHFHDTLGQSDDLIHHHHDYHHILHHH----HHQNHHPHSH 303
>gi|187936949 solute carrier family 39 (zinc transporter), member 10
[Homo sapiens]
Length = 831
Score = 483 bits (1242), Expect = e-136
Identities = 306/854 (35%), Positives = 447/854 (52%), Gaps = 126/854 (14%)
Query: 1 MARKLSVILILTFALSVTNPLHELK---AAAFPQTTEKISPNWESGINVDLAISTRQYHL 57
M K +I +LTF N HE A + ++ S + A + ++Y++
Sbjct: 5 MHTKFCLICLLTFIFHHCNHCHEEHDHGPEALHRQHRGMTELEPSKFSKQAAENEKKYYI 64
Query: 58 QQLFYRYGENNSLSVEGFRKLLQNIGIDKIKRIHIHHD---HDH--HSD----------H 102
++LF RYGEN LS G KLL N+G+ + K + I+H+ HDH H D H
Sbjct: 65 EKLFERYGENGRLSFFGLEKLLTNLGLGERKVVEINHEDLGHDHVSHLDILAVQEGKHFH 124
Query: 103 EHHSDHERH--------------------------------SDHEHHSDHEHHSDHDHHS 130
H+ H + SD +H DH H H H
Sbjct: 125 SHNHQHSHNHLNSENQTVTSVSTKRNHKCDPEKETVEVSVKSDDKHMHDHNHRLRHHHRL 184
Query: 131 HHN--HAASGKNKRKALCPDHDSDSSGKDP----RNSQGKGAHRPEHASGRRNVKDSVSA 184
HH+ H + ++ P + S + + + P+ ++ K + ++
Sbjct: 185 HHHLDHNNTHHFHNDSITPSERGEPSNEPSTETNKTQEQSDVKLPKGKRKKKGRKSNENS 244
Query: 185 SEVTSTVYNTVSEG-------THFLETIETPRPGKLFPKDVSSSTP--------PSVTSK 229
+T +G H + + P + + + P P +
Sbjct: 245 EVITPGFPPNHDQGEQYEHNRVHKPDRVHNPGHSHVHLPERNGHDPGRGHQDLDPDNEGE 304
Query: 230 SRVSRL--AGRKTNESVSEPRKGFMYSRNTNENPQECFNASKLLTSHGMGIQVPLNATEF 287
R +R A N ++ RK N +++ EC N ++LL +G G P++ F
Sbjct: 305 LRHTRKREAPHVKNNAIISLRKDL----NEDDHHHECLNVTQLLKYYGHGANSPISTDLF 360
Query: 288 NYLCPAIINQIDARSCLIHTSEKKAEIPPKTYSL---------QIAWVGGFIAISIISFL 338
YLCPA++ QID+R C+ H + E K +L AW+ G I+I++IS L
Sbjct: 361 TYLCPALLYQIDSRLCIEHFDKLLVEDINKDKNLVPEDEANIGASAWICGIISITVISLL 420
Query: 339 SLLGVILVPLMNRVFFKFLLSFLVALAVGTLSGDAFLHLLPHSHASHHHSHSHEEPAMEM 398
SLLGVILVP++N+ FKFLL+FLVALAVGT+SGDA LHLLPHS H HSH H
Sbjct: 421 SLLGVILVPIINQGCFKFLLTFLVALAVGTMSGDALLHLLPHSQGGHDHSHQHAHG---- 476
Query: 399 KRGPLFSHLSSQNIEESAYFDSTWKGLTALGGLYFMFLVEHVLTLIKQFKDKKKKNQK-K 457
G H S++ +EE +D+ KGL ALGG+Y +F++EH + + K +K ++ K +
Sbjct: 477 -HGHSHGHESNKFLEE---YDAVLKGLVALGGIYLLFIIEHCIRMFKHYKQQRGKQKWFM 532
Query: 458 PENDDDVEIKKQLSKYESQLSTNEEKVD------TDDRTEGYLRADSQEPSHFDSQQPA- 510
+N ++ I ++LS ++ + + + + TDD R + E + + QQ +
Sbjct: 533 KQNTEESTIGRKLSDHKLNNTPDSDWLQLKPLAGTDDSVVSEDRLNETELTDLEGQQESP 592
Query: 511 ----VLEEEEVMIAHAHPQEVYNEYVPRGCKNKCHSHFHDTLGQSDDLIHHHHDYHHILH 566
+ EEE +I H+H ++ + ++ H+ H+ HH + +L
Sbjct: 593 PKNYLCIEEEKIIDHSHSDGLHTIH-----EHDLHAAAHN----------HHGENKTVLR 637
Query: 567 HHHHQNHHPHSHSQR---YSREELKDAGVATLAWMVIMGDGLHNFSDGLAIGAAFTEGLS 623
H+HQ HH HSH +S +LK+ G+A +AWMVIMGDG+HNFSDGLAIGAAF+ GL+
Sbjct: 638 KHNHQWHHKHSHHSHGPCHSGSDLKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAGLT 697
Query: 624 SGLSTSVAVFCHELPHELGDFAVLLKAGMTVKQAVLYNALSAMLAYLGMATGIFIGHYAE 683
G+STS+AVFCHELPHELGDFAVLLKAGMTVKQA++YN LSAM+AY+GM G +G YA
Sbjct: 698 GGISTSIAVFCHELPHELGDFAVLLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAVGQYAN 757
Query: 684 NVSMWIFALTAGLFMYVALVDMVPEMLHNDA--SDHGCSRWGYFFLQNAGMLLGFGIMLL 741
N+++WIFA+TAG+F+YVALVDM+PEMLH D +HG G F LQN G+L GF IML+
Sbjct: 758 NITLWIFAVTAGMFLYVALVDMLPEMLHGDGDNEEHGFCPVGQFILQNLGLLFGFAIMLV 817
Query: 742 ISIFEHKIVFRINF 755
I+++E KIVF I F
Sbjct: 818 IALYEDKIVFDIQF 831
>gi|55741750 solute carrier family 39 (zinc transporter), member 10
[Homo sapiens]
Length = 831
Score = 483 bits (1242), Expect = e-136
Identities = 306/854 (35%), Positives = 447/854 (52%), Gaps = 126/854 (14%)
Query: 1 MARKLSVILILTFALSVTNPLHELK---AAAFPQTTEKISPNWESGINVDLAISTRQYHL 57
M K +I +LTF N HE A + ++ S + A + ++Y++
Sbjct: 5 MHTKFCLICLLTFIFHHCNHCHEEHDHGPEALHRQHRGMTELEPSKFSKQAAENEKKYYI 64
Query: 58 QQLFYRYGENNSLSVEGFRKLLQNIGIDKIKRIHIHHD---HDH--HSD----------H 102
++LF RYGEN LS G KLL N+G+ + K + I+H+ HDH H D H
Sbjct: 65 EKLFERYGENGRLSFFGLEKLLTNLGLGERKVVEINHEDLGHDHVSHLDILAVQEGKHFH 124
Query: 103 EHHSDHERH--------------------------------SDHEHHSDHEHHSDHDHHS 130
H+ H + SD +H DH H H H
Sbjct: 125 SHNHQHSHNHLNSENQTVTSVSTKRNHKCDPEKETVEVSVKSDDKHMHDHNHRLRHHHRL 184
Query: 131 HHN--HAASGKNKRKALCPDHDSDSSGKDP----RNSQGKGAHRPEHASGRRNVKDSVSA 184
HH+ H + ++ P + S + + + P+ ++ K + ++
Sbjct: 185 HHHLDHNNTHHFHNDSITPSERGEPSNEPSTETNKTQEQSDVKLPKGKRKKKGRKSNENS 244
Query: 185 SEVTSTVYNTVSEG-------THFLETIETPRPGKLFPKDVSSSTP--------PSVTSK 229
+T +G H + + P + + + P P +
Sbjct: 245 EVITPGFPPNHDQGEQYEHNRVHKPDRVHNPGHSHVHLPERNGHDPGRGHQDLDPDNEGE 304
Query: 230 SRVSRL--AGRKTNESVSEPRKGFMYSRNTNENPQECFNASKLLTSHGMGIQVPLNATEF 287
R +R A N ++ RK N +++ EC N ++LL +G G P++ F
Sbjct: 305 LRHTRKREAPHVKNNAIISLRKDL----NEDDHHHECLNVTQLLKYYGHGANSPISTDLF 360
Query: 288 NYLCPAIINQIDARSCLIHTSEKKAEIPPKTYSL---------QIAWVGGFIAISIISFL 338
YLCPA++ QID+R C+ H + E K +L AW+ G I+I++IS L
Sbjct: 361 TYLCPALLYQIDSRLCIEHFDKLLVEDINKDKNLVPEDEANIGASAWICGIISITVISLL 420
Query: 339 SLLGVILVPLMNRVFFKFLLSFLVALAVGTLSGDAFLHLLPHSHASHHHSHSHEEPAMEM 398
SLLGVILVP++N+ FKFLL+FLVALAVGT+SGDA LHLLPHS H HSH H
Sbjct: 421 SLLGVILVPIINQGCFKFLLTFLVALAVGTMSGDALLHLLPHSQGGHDHSHQHAHG---- 476
Query: 399 KRGPLFSHLSSQNIEESAYFDSTWKGLTALGGLYFMFLVEHVLTLIKQFKDKKKKNQK-K 457
G H S++ +EE +D+ KGL ALGG+Y +F++EH + + K +K ++ K +
Sbjct: 477 -HGHSHGHESNKFLEE---YDAVLKGLVALGGIYLLFIIEHCIRMFKHYKQQRGKQKWFM 532
Query: 458 PENDDDVEIKKQLSKYESQLSTNEEKVD------TDDRTEGYLRADSQEPSHFDSQQPA- 510
+N ++ I ++LS ++ + + + + TDD R + E + + QQ +
Sbjct: 533 KQNTEESTIGRKLSDHKLNNTPDSDWLQLKPLAGTDDSVVSEDRLNETELTDLEGQQESP 592
Query: 511 ----VLEEEEVMIAHAHPQEVYNEYVPRGCKNKCHSHFHDTLGQSDDLIHHHHDYHHILH 566
+ EEE +I H+H ++ + ++ H+ H+ HH + +L
Sbjct: 593 PKNYLCIEEEKIIDHSHSDGLHTIH-----EHDLHAAAHN----------HHGENKTVLR 637
Query: 567 HHHHQNHHPHSHSQR---YSREELKDAGVATLAWMVIMGDGLHNFSDGLAIGAAFTEGLS 623
H+HQ HH HSH +S +LK+ G+A +AWMVIMGDG+HNFSDGLAIGAAF+ GL+
Sbjct: 638 KHNHQWHHKHSHHSHGPCHSGSDLKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAGLT 697
Query: 624 SGLSTSVAVFCHELPHELGDFAVLLKAGMTVKQAVLYNALSAMLAYLGMATGIFIGHYAE 683
G+STS+AVFCHELPHELGDFAVLLKAGMTVKQA++YN LSAM+AY+GM G +G YA
Sbjct: 698 GGISTSIAVFCHELPHELGDFAVLLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAVGQYAN 757
Query: 684 NVSMWIFALTAGLFMYVALVDMVPEMLHNDA--SDHGCSRWGYFFLQNAGMLLGFGIMLL 741
N+++WIFA+TAG+F+YVALVDM+PEMLH D +HG G F LQN G+L GF IML+
Sbjct: 758 NITLWIFAVTAGMFLYVALVDMLPEMLHGDGDNEEHGFCPVGQFILQNLGLLFGFAIMLV 817
Query: 742 ISIFEHKIVFRINF 755
I+++E KIVF I F
Sbjct: 818 IALYEDKIVFDIQF 831
>gi|205830424 solute carrier family 39 (zinc transporter), member 14
isoform a [Homo sapiens]
Length = 492
Score = 221 bits (562), Expect = 3e-57
Identities = 152/501 (30%), Positives = 232/501 (46%), Gaps = 105/501 (20%)
Query: 258 NENPQECFNASKLLTSHGMGIQVPLNATEFNYLCPAIINQIDARSCLIHT--SEKKAEIP 315
+ N CF++ L T+H Q + ++E CP I+ Q+D+R+C +E+ +
Sbjct: 85 HRNLSTCFSSGDLFTAHNFSEQSRIGSSELQEFCPTILQQLDSRACTSENQENEENEQTE 144
Query: 316 PKTYSLQIAWVGGFIAISIISFLSLLGVILVPLMNRVFFKFLLSFLVALAVGTLSGDAFL 375
S W G + +++IS SLLG +VP M + F+K LL + +ALA+GTL +A
Sbjct: 145 EGRPSAVEVWGYGLLCVTVISLCSLLGASVVPFMKKTFYKRLLLYFIALAIGTLYSNALF 204
Query: 376 HLLPHSHASHHHSHSHEEPAMEMKRGPLFSHLSSQNIEESAYFDSTWKGLTALGGLYFMF 435
L+P + F+ L + +SA GG Y F
Sbjct: 205 QLIPEAFG--------------------FNPLEDYYVSKSA---------VVFGGFYLFF 235
Query: 436 LVEHVLTLIKQFKDKKKKNQKKPENDDDVEIKKQLSKYESQLSTNEEKVDTDDRTEGYLR 495
E +L ++ K+KN+ + + L + Q EK+ D
Sbjct: 236 FTEKILKILL-----KQKNEH--HHGHSHYASESLPSKKDQEEGVMEKLQNGD------- 281
Query: 496 ADSQEPSHFDSQQP--AVLEEEEVMIAHAHPQEVYNEYVPRGCKNKCHSHFHDTLGQSDD 553
D P H S+ A + +E+V++ Q++
Sbjct: 282 LDHMIPQHCSSELDGKAPMVDEKVIVGSLSVQDLQA------------------------ 317
Query: 554 LIHHHHDYHHILHHHHHQNHHPHSHSQRYSREELKDAGVATLAWMVIMGDGLHNFSDGLA 613
S S Y + ++ + + TLAWM+ + DGLHNF DGLA
Sbjct: 318 -----------------------SQSACYWLKGVRYSDIGTLAWMITLSDGLHNFIDGLA 354
Query: 614 IGAAFTEGLSSGLSTSVAVFCHELPHELGDFAVLLKAGMTVKQAVLYNALSAMLAYLGMA 673
IGA+FT + G+STSVA+ C E PHELGDF +LL AGM+++QA+ +N LSA YLG+A
Sbjct: 355 IGASFTVSVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLSACCCYLGLA 414
Query: 674 TGIFIG-HYAENVSMWIFALTAGLFMYVALVDMVPEMLHNDASDHGCSRWGY----FFLQ 728
GI G H++ N WIFAL G+F+Y++L DM PEM D R G F +Q
Sbjct: 415 FGILAGSHFSAN---WIFALAGGMFLYISLADMFPEMNEVCQED---ERKGSILIPFIIQ 468
Query: 729 NAGMLLGFGIMLLISIFEHKI 749
N G+L GF IM++++++ +I
Sbjct: 469 NLGLLTGFTIMVVLTMYSGQI 489
>gi|190360568 solute carrier family 39 (zinc transporter), member 14
isoform a [Homo sapiens]
Length = 492
Score = 221 bits (562), Expect = 3e-57
Identities = 152/501 (30%), Positives = 232/501 (46%), Gaps = 105/501 (20%)
Query: 258 NENPQECFNASKLLTSHGMGIQVPLNATEFNYLCPAIINQIDARSCLIHT--SEKKAEIP 315
+ N CF++ L T+H Q + ++E CP I+ Q+D+R+C +E+ +
Sbjct: 85 HRNLSTCFSSGDLFTAHNFSEQSRIGSSELQEFCPTILQQLDSRACTSENQENEENEQTE 144
Query: 316 PKTYSLQIAWVGGFIAISIISFLSLLGVILVPLMNRVFFKFLLSFLVALAVGTLSGDAFL 375
S W G + +++IS SLLG +VP M + F+K LL + +ALA+GTL +A
Sbjct: 145 EGRPSAVEVWGYGLLCVTVISLCSLLGASVVPFMKKTFYKRLLLYFIALAIGTLYSNALF 204
Query: 376 HLLPHSHASHHHSHSHEEPAMEMKRGPLFSHLSSQNIEESAYFDSTWKGLTALGGLYFMF 435
L+P + F+ L + +SA GG Y F
Sbjct: 205 QLIPEAFG--------------------FNPLEDYYVSKSA---------VVFGGFYLFF 235
Query: 436 LVEHVLTLIKQFKDKKKKNQKKPENDDDVEIKKQLSKYESQLSTNEEKVDTDDRTEGYLR 495
E +L ++ K+KN+ + + L + Q EK+ D
Sbjct: 236 FTEKILKILL-----KQKNEH--HHGHSHYASESLPSKKDQEEGVMEKLQNGD------- 281
Query: 496 ADSQEPSHFDSQQP--AVLEEEEVMIAHAHPQEVYNEYVPRGCKNKCHSHFHDTLGQSDD 553
D P H S+ A + +E+V++ Q++
Sbjct: 282 LDHMIPQHCSSELDGKAPMVDEKVIVGSLSVQDLQA------------------------ 317
Query: 554 LIHHHHDYHHILHHHHHQNHHPHSHSQRYSREELKDAGVATLAWMVIMGDGLHNFSDGLA 613
S S Y + ++ + + TLAWM+ + DGLHNF DGLA
Sbjct: 318 -----------------------SQSACYWLKGVRYSDIGTLAWMITLSDGLHNFIDGLA 354
Query: 614 IGAAFTEGLSSGLSTSVAVFCHELPHELGDFAVLLKAGMTVKQAVLYNALSAMLAYLGMA 673
IGA+FT + G+STSVA+ C E PHELGDF +LL AGM+++QA+ +N LSA YLG+A
Sbjct: 355 IGASFTVSVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLSACCCYLGLA 414
Query: 674 TGIFIG-HYAENVSMWIFALTAGLFMYVALVDMVPEMLHNDASDHGCSRWGY----FFLQ 728
GI G H++ N WIFAL G+F+Y++L DM PEM D R G F +Q
Sbjct: 415 FGILAGSHFSAN---WIFALAGGMFLYISLADMFPEMNEVCQED---ERKGSILIPFIIQ 468
Query: 729 NAGMLLGFGIMLLISIFEHKI 749
N G+L GF IM++++++ +I
Sbjct: 469 NLGLLTGFTIMVVLTMYSGQI 489
>gi|190358541 solute carrier family 39 (zinc transporter), member 14
isoform b [Homo sapiens]
Length = 492
Score = 220 bits (561), Expect = 3e-57
Identities = 150/501 (29%), Positives = 235/501 (46%), Gaps = 105/501 (20%)
Query: 258 NENPQECFNASKLLTSHGMGIQVPLNATEFNYLCPAIINQIDARSCLIHT--SEKKAEIP 315
+ N CF++ L T+H Q + ++E CP I+ Q+D+R+C +E+ +
Sbjct: 85 HRNLSTCFSSGDLFTAHNFSEQSRIGSSELQEFCPTILQQLDSRACTSENQENEENEQTE 144
Query: 316 PKTYSLQIAWVGGFIAISIISFLSLLGVILVPLMNRVFFKFLLSFLVALAVGTLSGDAFL 375
S W GF+++S+I+ SLLGV+++P + FF +L++ +AL++GTL +A
Sbjct: 145 EGRPSAVEVWGFGFLSVSLINLASLLGVLVLPCTEKAFFSRVLTYFIALSIGTLLSNALF 204
Query: 376 HLLPHSHASHHHSHSHEEPAMEMKRGPLFSHLSSQNIEESAYFDSTWKGLTALGGLYFMF 435
L+P + F+ L + +SA GG Y F
Sbjct: 205 QLIPEAFG--------------------FNPLEDYYVSKSA---------VVFGGFYLFF 235
Query: 436 LVEHVLTLIKQFKDKKKKNQKKPENDDDVEIKKQLSKYESQLSTNEEKVDTDDRTEGYLR 495
E +L ++ K+KN+ + + L + Q EK+ D
Sbjct: 236 FTEKILKILL-----KQKNEH--HHGHSHYASESLPSKKDQEEGVMEKLQNGD------- 281
Query: 496 ADSQEPSHFDSQQP--AVLEEEEVMIAHAHPQEVYNEYVPRGCKNKCHSHFHDTLGQSDD 553
D P H S+ A + +E+V++ Q++
Sbjct: 282 LDHMIPQHCSSELDGKAPMVDEKVIVGSLSVQDLQA------------------------ 317
Query: 554 LIHHHHDYHHILHHHHHQNHHPHSHSQRYSREELKDAGVATLAWMVIMGDGLHNFSDGLA 613
S S Y + ++ + + TLAWM+ + DGLHNF DGLA
Sbjct: 318 -----------------------SQSACYWLKGVRYSDIGTLAWMITLSDGLHNFIDGLA 354
Query: 614 IGAAFTEGLSSGLSTSVAVFCHELPHELGDFAVLLKAGMTVKQAVLYNALSAMLAYLGMA 673
IGA+FT + G+STSVA+ C E PHELGDF +LL AGM+++QA+ +N LSA YLG+A
Sbjct: 355 IGASFTVSVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLSACCCYLGLA 414
Query: 674 TGIFIG-HYAENVSMWIFALTAGLFMYVALVDMVPEMLHNDASDHGCSRWGY----FFLQ 728
GI G H++ N WIFAL G+F+Y++L DM PEM D R G F +Q
Sbjct: 415 FGILAGSHFSAN---WIFALAGGMFLYISLADMFPEMNEVCQED---ERKGSILIPFIIQ 468
Query: 729 NAGMLLGFGIMLLISIFEHKI 749
N G+L GF IM++++++ +I
Sbjct: 469 NLGLLTGFTIMVVLTMYSGQI 489
>gi|205830426 solute carrier family 39 (zinc transporter), member 14
isoform c [Homo sapiens]
Length = 481
Score = 202 bits (514), Expect = 9e-52
Identities = 136/454 (29%), Positives = 208/454 (45%), Gaps = 98/454 (21%)
Query: 258 NENPQECFNASKLLTSHGMGIQVPLNATEFNYLCPAIINQIDARSCLIHT--SEKKAEIP 315
+ N CF++ L T+H Q + ++E CP I+ Q+D+R+C +E+ +
Sbjct: 85 HRNLSTCFSSGDLFTAHNFSEQSRIGSSELQEFCPTILQQLDSRACTSENQENEENEQTE 144
Query: 316 PKTYSLQIAWVGGFIAISIISFLSLLGVILVPLMNRVFFKFLLSFLVALAVGTLSGDAFL 375
S W G + +++IS SLLG +VP M + F+K LL + +ALA+GTL +A
Sbjct: 145 EGRPSAVEVWGYGLLCVTVISLCSLLGASVVPFMKKTFYKRLLLYFIALAIGTLYSNALF 204
Query: 376 HLLPHSHASHHHSHSHEEPAMEMKRGPLFSHLSSQNIEESAYFDSTWKGLTALGGLYFMF 435
L+P + F+ L + +SA GG Y F
Sbjct: 205 QLIPEAFG--------------------FNPLEDYYVSKSA---------VVFGGFYLFF 235
Query: 436 LVEHVLTLIKQFKDKKKKNQKKPENDDDVEIKKQLSKYESQLSTNEEKVDTDDRTEGYLR 495
E +L ++ K+KN+ + + L + Q EK+ D
Sbjct: 236 FTEKILKILL-----KQKNEH--HHGHSHYASESLPSKKDQEEGVMEKLQNGD------- 281
Query: 496 ADSQEPSHFDSQQP--AVLEEEEVMIAHAHPQEVYNEYVPRGCKNKCHSHFHDTLGQSDD 553
D P H S+ A + +E+V++ Q++
Sbjct: 282 LDHMIPQHCSSELDGKAPMVDEKVIVGSLSVQDLQA------------------------ 317
Query: 554 LIHHHHDYHHILHHHHHQNHHPHSHSQRYSREELKDAGVATLAWMVIMGDGLHNFSDGLA 613
S S Y + ++ + + TLAWM+ + DGLHNF DGLA
Sbjct: 318 -----------------------SQSACYWLKGVRYSDIGTLAWMITLSDGLHNFIDGLA 354
Query: 614 IGAAFTEGLSSGLSTSVAVFCHELPHELGDFAVLLKAGMTVKQAVLYNALSAMLAYLGMA 673
IGA+FT + G+STSVA+ C E PHELGDF +LL AGM+++QA+ +N LSA YLG+A
Sbjct: 355 IGASFTVSVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLSACCCYLGLA 414
Query: 674 TGIFIG-HYAENVSMWIFALTAGLFMYVALVDMV 706
GI G H++ N WIFAL G+F+Y++L DM+
Sbjct: 415 FGILAGSHFSAN---WIFALAGGMFLYISLADMM 445
>gi|223633939 solute carrier family 39 (zinc transporter), member 12
isoform 1 [Homo sapiens]
Length = 691
Score = 156 bits (394), Expect = 8e-38
Identities = 74/162 (45%), Positives = 115/162 (70%), Gaps = 5/162 (3%)
Query: 588 KDAGVATLAWMVIMGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAVFCHELPHELGDFAVL 647
K ++ LA M+++GD LHNF+DGLAIGAAF+ SG++T++A+ CHE+PHE+GDFAVL
Sbjct: 533 KCKAISLLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVL 592
Query: 648 LKAGMTVKQAVLYNALSAMLAYLGMATGIFIGHYAENVSMWIFALTAGLFMYVALVDMVP 707
L +G+++K A+L N +S++ A++G+ G+ + V WIF +TAG+F+Y++LV+M+P
Sbjct: 593 LSSGLSMKTAILMNFISSLTAFMGLYIGLSVS-ADPCVQDWIFTVTAGMFLYLSLVEMLP 651
Query: 708 EMLHNDASDHGCSRWGYFFLQNAGMLLGFGIMLLISIFEHKI 749
EM H W F LQN G++LG+ +LL++I+E I
Sbjct: 652 EMTHVQTQ----RPWMMFLLQNFGLILGWLSLLLLAIYEQNI 689
Score = 69.3 bits (168), Expect = 1e-11
Identities = 53/194 (27%), Positives = 91/194 (46%), Gaps = 30/194 (15%)
Query: 262 QECFNASKLLT---SHGMGIQVPLNATEFNYLCPAIINQIDARSCLIHTSEKKAEIPPKT 318
Q CF+A +L+ G+ + ++ +F + P II Q+ + SC + +++A++PP T
Sbjct: 308 QTCFSARQLVEIFLQKGLSL---ISKEDFKQMSPGIIQQLLSCSCHL-PKDQQAKLPPTT 363
Query: 319 YSLQIAWVGGFIAISIISFLSLLGVILVPLMN-RVFFKFLLSFLVALAVGTLSGDAFLHL 377
+ +A+++++ S+LG LV + ++ +L V LAVGTLSGDA LHL
Sbjct: 364 LE---KYGYSTVAVTLLTLGSMLGTALVLFHSCEENYRLILQLFVGLAVGTLSGDALLHL 420
Query: 378 LPHSHASHHHSHSHEEPAMEMKRGPLFSHLSSQNIEESAYFDSTWKGLTALGGLYFMFLV 437
+P H + P F H WK + +GG++ FL+
Sbjct: 421 IPQVLGLH------------KQEAPEFGHFHESK-------GHIWKLMGLIGGIHGFFLI 461
Query: 438 EHVLTLIKQFKDKK 451
E L+ DK+
Sbjct: 462 EKCFILLVSPNDKQ 475
>gi|223633937 solute carrier family 39 (zinc transporter), member 12
isoform 2 [Homo sapiens]
Length = 654
Score = 156 bits (394), Expect = 8e-38
Identities = 74/162 (45%), Positives = 115/162 (70%), Gaps = 5/162 (3%)
Query: 588 KDAGVATLAWMVIMGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAVFCHELPHELGDFAVL 647
K ++ LA M+++GD LHNF+DGLAIGAAF+ SG++T++A+ CHE+PHE+GDFAVL
Sbjct: 496 KCKAISLLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVL 555
Query: 648 LKAGMTVKQAVLYNALSAMLAYLGMATGIFIGHYAENVSMWIFALTAGLFMYVALVDMVP 707
L +G+++K A+L N +S++ A++G+ G+ + V WIF +TAG+F+Y++LV+M+P
Sbjct: 556 LSSGLSMKTAILMNFISSLTAFMGLYIGLSVS-ADPCVQDWIFTVTAGMFLYLSLVEMLP 614
Query: 708 EMLHNDASDHGCSRWGYFFLQNAGMLLGFGIMLLISIFEHKI 749
EM H W F LQN G++LG+ +LL++I+E I
Sbjct: 615 EMTHVQTQ----RPWMMFLLQNFGLILGWLSLLLLAIYEQNI 652
Score = 71.2 bits (173), Expect = 3e-12
Identities = 57/209 (27%), Positives = 96/209 (45%), Gaps = 35/209 (16%)
Query: 262 QECFNASKLLT---SHGMGIQVPLNATEFNYLCPAIINQIDARSCLIHTSEKKAEIPPKT 318
Q CF+A +L+ G+ + ++ +F + P II Q+ + SC + +++A++PP T
Sbjct: 308 QTCFSARQLVEIFLQKGLSL---ISKEDFKQMSPGIIQQLLSCSCHL-PKDQQAKLPPTT 363
Query: 319 YSLQIAWVGGFIAISIISFLSLLGVILVPLMN-RVFFKFLLSFLVALAVGTLSGDAFLHL 377
+ +A+++++ S+LG LV + ++ +L V LAVGTLSGDA LHL
Sbjct: 364 LE---KYGYSTVAVTLLTLGSMLGTALVLFHSCEENYRLILQLFVGLAVGTLSGDALLHL 420
Query: 378 LPHSHASHHHSHSHEEPAMEMKRGPLFSHLSSQNIEESAYFDSTWKGLTALGGLYFMFLV 437
+P H + P F H WK + +GG++ FL+
Sbjct: 421 IPQVLGLH------------KQEAPEFGHFHESK-------GHIWKLMGLIGGIHGFFLI 461
Query: 438 EHVLTLIKQFKDKKKKNQKKPENDDDVEI 466
E L+ DK K PE+ E+
Sbjct: 462 EKCFILLVSPNDK-----KSPEDSQAAEM 485
>gi|206597541 solute carrier family 39 (metal ion transporter),
member 5 [Homo sapiens]
Length = 540
Score = 156 bits (394), Expect = 8e-38
Identities = 79/178 (44%), Positives = 116/178 (65%), Gaps = 13/178 (7%)
Query: 573 HHPHSHSQRYSREELKDAGVATLAWMVIMGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAV 632
H HSH + G + WMV++GDGLHN +DGLAIGAAF++G SSGLST++AV
Sbjct: 370 HQGHSHGHQ---------GGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAV 420
Query: 633 FCHELPHELGDFAVLLKAGMTVKQAVLYNALSAMLAYLGMATGIFIGHYAENVSMWIFAL 692
FCHELPHELGDFA+LL++G++ ++ +L + +S L G G+ + ++ W+F +
Sbjct: 421 FCHELPHELGDFAMLLQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGV 480
Query: 693 TAGLFMYVALVDMVPEMLHNDASDHGCSRWGYFFLQNAGMLLGFGIMLLISIFEHKIV 750
TAG+F+YVALVDM+P +L + LQ G+LLG G+ML I++ E +++
Sbjct: 481 TAGVFLYVALVDMLPALLRPPEP----LPTPHVLLQGLGLLLGGGLMLAITLLEERLL 534
Score = 95.5 bits (236), Expect = 2e-19
Identities = 70/240 (29%), Positives = 113/240 (47%), Gaps = 33/240 (13%)
Query: 262 QECFNASKLLTSHGMGIQVPLNATEFNYLCPAIINQIDARSCLIHTSEKKAEIPPKTYSL 321
++C N S+LL + G+ PL +F LCPA++ QID+R C+ A P L
Sbjct: 156 EDCLNGSQLLVNFGLSPAAPLTPRQFALLCPALLYQIDSRVCI------GAPAPAPPGDL 209
Query: 322 QIAWVGGFIAISIISFLSLLGVILVPLMNRVFFKFLLSFLVALAVGTLSGDAFLHLLPHS 381
A + +A+ ++S S L ++L+ L+ + LL FL ALAVGTL GDA LHLLPH+
Sbjct: 210 LSALLQSALAVLLLSLPSPLSLLLLRLLGPRLLRPLLGFLGALAVGTLCGDALLHLLPHA 269
Query: 382 HASHHHSHSHEEPAMEMKRGPLFSHLSSQNIEESAYFDSTWKGLTALGGLYFMFLVEHVL 441
H E GP GL+ LGGL+ +F++E++L
Sbjct: 270 QEGRHAGPGG---LPEKDLGP---------------------GLSVLGGLFLLFVLENML 305
Query: 442 TLIKQFKDKKKKNQKKPENDDDVEIKKQLSKYESQLSTNEEKVDTDDRTEGYLRADSQEP 501
L++ + + ++K N +E + + S ++ + + +G +SQ P
Sbjct: 306 GLLRHRGLRPRCCRRKRRN---LETRNLDPENGSGMALQPLQAAPEPGAQGQREKNSQHP 362
Score = 36.2 bits (82), Expect = 0.12
Identities = 15/48 (31%), Positives = 30/48 (62%)
Query: 45 NVDLAISTRQYHLQQLFYRYGENNSLSVEGFRKLLQNIGIDKIKRIHI 92
N+ A + ++L QLF YGEN +L+ G +LL ++G+ +++ + +
Sbjct: 28 NLGPAEQEQNHYLAQLFGLYGENGTLTAGGLARLLHSLGLGRVQGLRL 75
>gi|206597539 solute carrier family 39 (metal ion transporter),
member 5 [Homo sapiens]
Length = 540
Score = 156 bits (394), Expect = 8e-38
Identities = 79/178 (44%), Positives = 116/178 (65%), Gaps = 13/178 (7%)
Query: 573 HHPHSHSQRYSREELKDAGVATLAWMVIMGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAV 632
H HSH + G + WMV++GDGLHN +DGLAIGAAF++G SSGLST++AV
Sbjct: 370 HQGHSHGHQ---------GGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAV 420
Query: 633 FCHELPHELGDFAVLLKAGMTVKQAVLYNALSAMLAYLGMATGIFIGHYAENVSMWIFAL 692
FCHELPHELGDFA+LL++G++ ++ +L + +S L G G+ + ++ W+F +
Sbjct: 421 FCHELPHELGDFAMLLQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGV 480
Query: 693 TAGLFMYVALVDMVPEMLHNDASDHGCSRWGYFFLQNAGMLLGFGIMLLISIFEHKIV 750
TAG+F+YVALVDM+P +L + LQ G+LLG G+ML I++ E +++
Sbjct: 481 TAGVFLYVALVDMLPALLRPPEP----LPTPHVLLQGLGLLLGGGLMLAITLLEERLL 534
Score = 95.5 bits (236), Expect = 2e-19
Identities = 70/240 (29%), Positives = 113/240 (47%), Gaps = 33/240 (13%)
Query: 262 QECFNASKLLTSHGMGIQVPLNATEFNYLCPAIINQIDARSCLIHTSEKKAEIPPKTYSL 321
++C N S+LL + G+ PL +F LCPA++ QID+R C+ A P L
Sbjct: 156 EDCLNGSQLLVNFGLSPAAPLTPRQFALLCPALLYQIDSRVCI------GAPAPAPPGDL 209
Query: 322 QIAWVGGFIAISIISFLSLLGVILVPLMNRVFFKFLLSFLVALAVGTLSGDAFLHLLPHS 381
A + +A+ ++S S L ++L+ L+ + LL FL ALAVGTL GDA LHLLPH+
Sbjct: 210 LSALLQSALAVLLLSLPSPLSLLLLRLLGPRLLRPLLGFLGALAVGTLCGDALLHLLPHA 269
Query: 382 HASHHHSHSHEEPAMEMKRGPLFSHLSSQNIEESAYFDSTWKGLTALGGLYFMFLVEHVL 441
H E GP GL+ LGGL+ +F++E++L
Sbjct: 270 QEGRHAGPGG---LPEKDLGP---------------------GLSVLGGLFLLFVLENML 305
Query: 442 TLIKQFKDKKKKNQKKPENDDDVEIKKQLSKYESQLSTNEEKVDTDDRTEGYLRADSQEP 501
L++ + + ++K N +E + + S ++ + + +G +SQ P
Sbjct: 306 GLLRHRGLRPRCCRRKRRN---LETRNLDPENGSGMALQPLQAAPEPGAQGQREKNSQHP 362
Score = 36.2 bits (82), Expect = 0.12
Identities = 15/48 (31%), Positives = 30/48 (62%)
Query: 45 NVDLAISTRQYHLQQLFYRYGENNSLSVEGFRKLLQNIGIDKIKRIHI 92
N+ A + ++L QLF YGEN +L+ G +LL ++G+ +++ + +
Sbjct: 28 NLGPAEQEQNHYLAQLFGLYGENGTLTAGGLARLLHSLGLGRVQGLRL 75
>gi|24586665 solute carrier family 39 (zinc transporter), member 8
isoform a [Homo sapiens]
Length = 460
Score = 155 bits (392), Expect = 1e-37
Identities = 79/161 (49%), Positives = 112/161 (69%), Gaps = 6/161 (3%)
Query: 592 VATLAWMVIMGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAVFCHELPHELGDFAVLLKAG 651
+ T+AWM+ + D LHNF DGLAIGA+ T L GLSTS+A+ C E PHELGDF +LL AG
Sbjct: 300 IGTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVILLNAG 359
Query: 652 MTVKQAVLYNALSAMLAYLGMATGIFIG-HYAENVSMWIFALTAGLFMYVALVDMVPEM- 709
M+ +QA+L+N LSA Y+G+A GI +G ++A N+ IFAL G+F+Y++L DM PEM
Sbjct: 360 MSTRQALLFNFLSACSCYVGLAFGILVGNNFAPNI---IFALAGGMFLYISLADMFPEMN 416
Query: 710 -LHNDASDHGCSRWGYFFLQNAGMLLGFGIMLLISIFEHKI 749
+ + + + +F +QNAGML GF +LLI+++ +I
Sbjct: 417 DMLREKVTGRKTDFTFFMIQNAGMLTGFTAILLITLYAGEI 457
Score = 79.7 bits (195), Expect = 9e-15
Identities = 53/194 (27%), Positives = 95/194 (48%), Gaps = 15/194 (7%)
Query: 210 PGKLFPKDVSSSTPPSVT-SKSRVSRLAGRKTNES-VSEPRKGFMYSRNTNENPQECFNA 267
PG F +DV S +++ S +++ L + S V P G ++ +C A
Sbjct: 25 PGLAFSEDVLSVFGANLSLSAAQLQHLLEQMGAASRVGVPEPGQLHFN-------QCLTA 77
Query: 268 SKLLTSHGMGIQVPLNATEFNYLCPAIINQIDARSCLIHTSEKKAEIPPKTYSLQIAWVG 327
++ + HG + +++F+ +CPA++ Q++ C K S W
Sbjct: 78 EEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPCEDRPKHKTRP------SHSEVWGY 131
Query: 328 GFIAISIISFLSLLGVILVPLMNRVFFKFLLSFLVALAVGTLSGDAFLHLLPHSHASHHH 387
GF++++II+ SLLG+IL PL+ + +F +L+F V LA+GTL +A L+P +
Sbjct: 132 GFLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQLIPEAFGFDPK 191
Query: 388 SHSHEEPAMEMKRG 401
S+ E A+ + G
Sbjct: 192 VDSYVEKAVAVFGG 205
>gi|205830407 solute carrier family 39 (zinc transporter), member 8
isoform c [Homo sapiens]
Length = 393
Score = 155 bits (392), Expect = 1e-37
Identities = 79/161 (49%), Positives = 112/161 (69%), Gaps = 6/161 (3%)
Query: 592 VATLAWMVIMGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAVFCHELPHELGDFAVLLKAG 651
+ T+AWM+ + D LHNF DGLAIGA+ T L GLSTS+A+ C E PHELGDF +LL AG
Sbjct: 233 IGTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVILLNAG 292
Query: 652 MTVKQAVLYNALSAMLAYLGMATGIFIG-HYAENVSMWIFALTAGLFMYVALVDMVPEM- 709
M+ +QA+L+N LSA Y+G+A GI +G ++A N+ IFAL G+F+Y++L DM PEM
Sbjct: 293 MSTRQALLFNFLSACSCYVGLAFGILVGNNFAPNI---IFALAGGMFLYISLADMFPEMN 349
Query: 710 -LHNDASDHGCSRWGYFFLQNAGMLLGFGIMLLISIFEHKI 749
+ + + + +F +QNAGML GF +LLI+++ +I
Sbjct: 350 DMLREKVTGRKTDFTFFMIQNAGMLTGFTAILLITLYAGEI 390
Score = 79.3 bits (194), Expect = 1e-14
Identities = 41/139 (29%), Positives = 73/139 (52%), Gaps = 6/139 (4%)
Query: 263 ECFNASKLLTSHGMGIQVPLNATEFNYLCPAIINQIDARSCLIHTSEKKAEIPPKTYSLQ 322
+C A ++ + HG + +++F+ +CPA++ Q++ C K S
Sbjct: 6 QCLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPCEDRPKHKTRP------SHS 59
Query: 323 IAWVGGFIAISIISFLSLLGVILVPLMNRVFFKFLLSFLVALAVGTLSGDAFLHLLPHSH 382
W GF++++II+ SLLG+IL PL+ + +F +L+F V LA+GTL +A L+P +
Sbjct: 60 EVWGYGFLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQLIPEAF 119
Query: 383 ASHHHSHSHEEPAMEMKRG 401
S+ E A+ + G
Sbjct: 120 GFDPKVDSYVEKAVAVFGG 138
>gi|205830403 solute carrier family 39 (zinc transporter), member 8
isoform a [Homo sapiens]
Length = 460
Score = 155 bits (392), Expect = 1e-37
Identities = 79/161 (49%), Positives = 112/161 (69%), Gaps = 6/161 (3%)
Query: 592 VATLAWMVIMGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAVFCHELPHELGDFAVLLKAG 651
+ T+AWM+ + D LHNF DGLAIGA+ T L GLSTS+A+ C E PHELGDF +LL AG
Sbjct: 300 IGTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVILLNAG 359
Query: 652 MTVKQAVLYNALSAMLAYLGMATGIFIG-HYAENVSMWIFALTAGLFMYVALVDMVPEM- 709
M+ +QA+L+N LSA Y+G+A GI +G ++A N+ IFAL G+F+Y++L DM PEM
Sbjct: 360 MSTRQALLFNFLSACSCYVGLAFGILVGNNFAPNI---IFALAGGMFLYISLADMFPEMN 416
Query: 710 -LHNDASDHGCSRWGYFFLQNAGMLLGFGIMLLISIFEHKI 749
+ + + + +F +QNAGML GF +LLI+++ +I
Sbjct: 417 DMLREKVTGRKTDFTFFMIQNAGMLTGFTAILLITLYAGEI 457
Score = 79.7 bits (195), Expect = 9e-15
Identities = 53/194 (27%), Positives = 95/194 (48%), Gaps = 15/194 (7%)
Query: 210 PGKLFPKDVSSSTPPSVT-SKSRVSRLAGRKTNES-VSEPRKGFMYSRNTNENPQECFNA 267
PG F +DV S +++ S +++ L + S V P G ++ +C A
Sbjct: 25 PGLAFSEDVLSVFGANLSLSAAQLQHLLEQMGAASRVGVPEPGQLHFN-------QCLTA 77
Query: 268 SKLLTSHGMGIQVPLNATEFNYLCPAIINQIDARSCLIHTSEKKAEIPPKTYSLQIAWVG 327
++ + HG + +++F+ +CPA++ Q++ C K S W
Sbjct: 78 EEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPCEDRPKHKTRP------SHSEVWGY 131
Query: 328 GFIAISIISFLSLLGVILVPLMNRVFFKFLLSFLVALAVGTLSGDAFLHLLPHSHASHHH 387
GF++++II+ SLLG+IL PL+ + +F +L+F V LA+GTL +A L+P +
Sbjct: 132 GFLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQLIPEAFGFDPK 191
Query: 388 SHSHEEPAMEMKRG 401
S+ E A+ + G
Sbjct: 192 VDSYVEKAVAVFGG 205
>gi|115430259 solute carrier family 39 (zinc transporter), member 4
isoform 1 [Homo sapiens]
Length = 622
Score = 154 bits (390), Expect = 2e-37
Identities = 77/157 (49%), Positives = 106/157 (67%), Gaps = 5/157 (3%)
Query: 595 LAWMVIMGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAVFCHELPHELGDFAVLLKAGMTV 654
L +M+ +GD +HNF+DGLA+GAAF +GL+TS+AVFCHELPHELGDFA LL AG++V
Sbjct: 471 LPYMITLGDAVHNFADGLAVGAAFASSWKTGLATSLAVFCHELPHELGDFAALLHAGLSV 530
Query: 655 KQAVLYNALSAMLAYLGMATGIFIGHYAENVSMWIFALTAGLFMYVALVDMVPEMLHNDA 714
+QA+L N SA+ A+ G+ + +G +E WI A+ GLF+YVAL DM+P ML
Sbjct: 531 RQALLLNLASALTAFAGLYVALAVG-VSEESEAWILAVATGLFLYVALCDMLPAML---- 585
Query: 715 SDHGCSRWGYFFLQNAGMLLGFGIMLLISIFEHKIVF 751
W F L N G+L G+ ++LL+S++E I F
Sbjct: 586 KVRDPRPWLLFLLHNVGLLGGWTVLLLLSLYEDDITF 622
Score = 60.5 bits (145), Expect = 6e-09
Identities = 47/182 (25%), Positives = 81/182 (44%), Gaps = 29/182 (15%)
Query: 264 CFNASKLLTSHGMGIQVPLNATEFNYLCPAIINQIDARSCLIHTSEKKAEIPPKTYSLQI 323
C +A ++ ++G+ Q + + L PA++ Q + +C TS+ + + + S
Sbjct: 245 CLSARDVMAAYGLSEQAGVTPEAWAQLSPALLQQQLSGAC---TSQSRPPVQDQL-SQSE 300
Query: 324 AWVGGFIAISIISFLSLLGVILVPLMN-RVFFKFLLSFLVALAVGTLSGDAFLHLLPHSH 382
++ G +A +I ++ G++L+ R ++L ++LAVG L+GDA LHL P
Sbjct: 301 RYLYGSLATLLICLCAVFGLLLLTCTGCRGVTHYILQTFLSLAVGALTGDAVLHLTPKVL 360
Query: 383 ASHHHSHSHEEPAMEMKRGPLFSHLSSQNIEESAYFDSTWKGLTALGGLYFMFLVEHVLT 442
H HS EE TW+ L L GLY FL E++
Sbjct: 361 GLHTHS------------------------EEGLSPQPTWRLLAMLAGLYAFFLFENLFN 396
Query: 443 LI 444
L+
Sbjct: 397 LL 398
>gi|115430255 solute carrier family 39 (zinc transporter), member 4
isoform 2 [Homo sapiens]
Length = 647
Score = 154 bits (390), Expect = 2e-37
Identities = 77/157 (49%), Positives = 106/157 (67%), Gaps = 5/157 (3%)
Query: 595 LAWMVIMGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAVFCHELPHELGDFAVLLKAGMTV 654
L +M+ +GD +HNF+DGLA+GAAF +GL+TS+AVFCHELPHELGDFA LL AG++V
Sbjct: 496 LPYMITLGDAVHNFADGLAVGAAFASSWKTGLATSLAVFCHELPHELGDFAALLHAGLSV 555
Query: 655 KQAVLYNALSAMLAYLGMATGIFIGHYAENVSMWIFALTAGLFMYVALVDMVPEMLHNDA 714
+QA+L N SA+ A+ G+ + +G +E WI A+ GLF+YVAL DM+P ML
Sbjct: 556 RQALLLNLASALTAFAGLYVALAVG-VSEESEAWILAVATGLFLYVALCDMLPAML---- 610
Query: 715 SDHGCSRWGYFFLQNAGMLLGFGIMLLISIFEHKIVF 751
W F L N G+L G+ ++LL+S++E I F
Sbjct: 611 KVRDPRPWLLFLLHNVGLLGGWTVLLLLSLYEDDITF 647
Score = 60.5 bits (145), Expect = 6e-09
Identities = 47/182 (25%), Positives = 81/182 (44%), Gaps = 29/182 (15%)
Query: 264 CFNASKLLTSHGMGIQVPLNATEFNYLCPAIINQIDARSCLIHTSEKKAEIPPKTYSLQI 323
C +A ++ ++G+ Q + + L PA++ Q + +C TS+ + + + S
Sbjct: 270 CLSARDVMAAYGLSEQAGVTPEAWAQLSPALLQQQLSGAC---TSQSRPPVQDQL-SQSE 325
Query: 324 AWVGGFIAISIISFLSLLGVILVPLMN-RVFFKFLLSFLVALAVGTLSGDAFLHLLPHSH 382
++ G +A +I ++ G++L+ R ++L ++LAVG L+GDA LHL P
Sbjct: 326 RYLYGSLATLLICLCAVFGLLLLTCTGCRGVTHYILQTFLSLAVGALTGDAVLHLTPKVL 385
Query: 383 ASHHHSHSHEEPAMEMKRGPLFSHLSSQNIEESAYFDSTWKGLTALGGLYFMFLVEHVLT 442
H HS EE TW+ L L GLY FL E++
Sbjct: 386 GLHTHS------------------------EEGLSPQPTWRLLAMLAGLYAFFLFENLFN 421
Query: 443 LI 444
L+
Sbjct: 422 LL 423
>gi|205830405 solute carrier family 39 (zinc transporter), member 8
isoform b [Homo sapiens]
Length = 444
Score = 139 bits (349), Expect = 1e-32
Identities = 69/132 (52%), Positives = 92/132 (69%), Gaps = 6/132 (4%)
Query: 592 VATLAWMVIMGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAVFCHELPHELGDFAVLLKAG 651
+ T+AWM+ + D LHNF DGLAIGA+ T L GLSTS+A+ C E PHELGDF +LL AG
Sbjct: 300 IGTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVILLNAG 359
Query: 652 MTVKQAVLYNALSAMLAYLGMATGIFIG-HYAENVSMWIFALTAGLFMYVALVDMVPEML 710
M+ +QA+L+N LSA Y+G+A GI +G ++A N+ IFAL G+F+Y++L DM PEM
Sbjct: 360 MSTRQALLFNFLSACSCYVGLAFGILVGNNFAPNI---IFALAGGMFLYISLADMFPEM- 415
Query: 711 HNDASDHGCSRW 722
ND +W
Sbjct: 416 -NDMLREKIIKW 426
Score = 79.7 bits (195), Expect = 9e-15
Identities = 53/194 (27%), Positives = 95/194 (48%), Gaps = 15/194 (7%)
Query: 210 PGKLFPKDVSSSTPPSVT-SKSRVSRLAGRKTNES-VSEPRKGFMYSRNTNENPQECFNA 267
PG F +DV S +++ S +++ L + S V P G ++ +C A
Sbjct: 25 PGLAFSEDVLSVFGANLSLSAAQLQHLLEQMGAASRVGVPEPGQLHFN-------QCLTA 77
Query: 268 SKLLTSHGMGIQVPLNATEFNYLCPAIINQIDARSCLIHTSEKKAEIPPKTYSLQIAWVG 327
++ + HG + +++F+ +CPA++ Q++ C K S W
Sbjct: 78 EEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPCEDRPKHKTRP------SHSEVWGY 131
Query: 328 GFIAISIISFLSLLGVILVPLMNRVFFKFLLSFLVALAVGTLSGDAFLHLLPHSHASHHH 387
GF++++II+ SLLG+IL PL+ + +F +L+F V LA+GTL +A L+P +
Sbjct: 132 GFLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQLIPEAFGFDPK 191
Query: 388 SHSHEEPAMEMKRG 401
S+ E A+ + G
Sbjct: 192 VDSYVEKAVAVFGG 205
>gi|117553619 solute carrier family 39, member 7 [Homo sapiens]
Length = 469
Score = 95.1 bits (235), Expect = 2e-19
Identities = 58/171 (33%), Positives = 92/171 (53%), Gaps = 14/171 (8%)
Query: 583 SREELKDAGVATLAWMVIMGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAVFCHELPHELG 642
+ EE + + ++ + D HNF+DGLAIGA+F G G+ T++ V HE+PHE+G
Sbjct: 306 AEEEKRGLDLRVSGYLNLAADLAHNFTDGLAIGASFRGGRGLGILTTMTVLLHEVPHEVG 365
Query: 643 DFAVLLKAGMTVKQAVLYNALSAMLAYLGMATGIFIGHYAENVSM-------WIFALTAG 695
DFA+L+++G + KQA+ L+A+ A G A + A + W+ TAG
Sbjct: 366 DFAILVQSGCSKKQAMRLQLLTAVGALAGTACALLTEGGAVGSEIAGGAGPGWVLPFTAG 425
Query: 696 LFMYVALVDMVPEMLHNDASDHGCSRWGYFFLQNAGMLLGFGIMLLISIFE 746
F+YVA V ++PE+L + L+ G+L G +M+LI+ E
Sbjct: 426 GFIYVATVSVLPELLREASPLQS-------LLEVLGLLGGVIMMVLIAHLE 469
Score = 46.2 bits (108), Expect = 1e-04
Identities = 30/85 (35%), Positives = 43/85 (50%), Gaps = 5/85 (5%)
Query: 325 WVGGFIAISIISFLSLLGVILVPL-MNRVFFKFLLSFLVALAVGTLSGDAFLHLLPHSHA 383
W A +IS + L+P+ N + LL L++ A G L GDAFLHL+PH+
Sbjct: 135 WAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLSFASGGLLGDAFLHLIPHALE 194
Query: 384 SHHHSHSHEEPA---MEMKRGPLFS 405
H H H+ E+P +GP+ S
Sbjct: 195 PHSH-HTLEQPGHGHSHSGQGPILS 218
Score = 44.3 bits (103), Expect = 4e-04
Identities = 22/66 (33%), Positives = 30/66 (45%), Gaps = 5/66 (7%)
Query: 91 HIHHD--HDHHSDHEH-HSDHERHSDHEHHSDHE--HHSDHDHHSHHNHAASGKNKRKAL 145
H H H H DH+H HS + H H H HE +H H H H+H G++ +
Sbjct: 66 HTHESIWHGHTHDHDHGHSHEDLHHGHSHGYSHESLYHRGHGHDHEHSHGGYGESGAPGI 125
Query: 146 CPDHDS 151
D D+
Sbjct: 126 KQDLDA 131
Score = 40.0 bits (92), Expect = 0.008
Identities = 24/76 (31%), Positives = 31/76 (40%), Gaps = 3/76 (3%)
Query: 91 HIHHDHDHHSDHEHHSDHERHSD-HEHHSDHEH-HSDHDHHSHHNHAASGKN-KRKALCP 147
H H D H H H H S H H DH+H HS D H H+H S ++ +
Sbjct: 49 HSHEDFHHGHSHAHGHGHTHESIWHGHTHDHDHGHSHEDLHHGHSHGYSHESLYHRGHGH 108
Query: 148 DHDSDSSGKDPRNSQG 163
DH+ G + G
Sbjct: 109 DHEHSHGGYGESGAPG 124
Score = 39.3 bits (90), Expect = 0.014
Identities = 30/87 (34%), Positives = 40/87 (45%), Gaps = 8/87 (9%)
Query: 494 LRADSQEPSHFDSQQPAVLEEEEVMIAHAHPQEVYNEYVPRGCKNKCHSHFHDTLGQSDD 553
L D QE H S + + E+ +HAH +E + G H+H HD +D
Sbjct: 34 LHDDLQEDFHGHSHRHSH-EDFHHGHSHAHGHGHTHESIWHG-----HTHDHDHGHSHED 87
Query: 554 LIH-HHHDY-HHILHHHHHQNHHPHSH 578
L H H H Y H L+H H + H HSH
Sbjct: 88 LHHGHSHGYSHESLYHRGHGHDHEHSH 114
Score = 38.5 bits (88), Expect = 0.023
Identities = 21/51 (41%), Positives = 24/51 (47%), Gaps = 3/51 (5%)
Query: 541 HSHFHDTLGQSDDLIHHHHDYHHILHHHHHQNHHPHSHSQRYSREELKDAG 591
HSH H G + + I H H + H H H HH HSH YS E L G
Sbjct: 58 HSHAHGH-GHTHESIWHGHTHDHDHGHSHEDLHHGHSHG--YSHESLYHRG 105
Score = 35.0 bits (79), Expect = 0.26
Identities = 15/43 (34%), Positives = 16/43 (37%), Gaps = 2/43 (4%)
Query: 94 HDHDHHSDHE--HHSDHERHSDHEHHSDHEHHSDHDHHSHHNH 134
H H H HE HH H H H HDH H+H
Sbjct: 43 HGHSHRHSHEDFHHGHSHAHGHGHTHESIWHGHTHDHDHGHSH 85
Score = 34.3 bits (77), Expect = 0.44
Identities = 23/89 (25%), Positives = 32/89 (35%), Gaps = 11/89 (12%)
Query: 90 IHIHHDHDHHSDHEHHSDHERHSDHEHHSDHEHHSD---HDHHSHHNHAASGKNKRKALC 146
+H D H HS + H H H H H + H H H+H S ++
Sbjct: 34 LHDDLQEDFHGHSHRHSHEDFHHGHSHAHGHGHTHESIWHGHTHDHDHGHSHEDL----- 88
Query: 147 PDHDSDSSGKDPRNSQGKG-AHRPEHASG 174
H S G + +G H EH+ G
Sbjct: 89 --HHGHSHGYSHESLYHRGHGHDHEHSHG 115
Score = 31.6 bits (70), Expect = 2.8
Identities = 16/39 (41%), Positives = 18/39 (46%), Gaps = 2/39 (5%)
Query: 541 HSHFHDTLGQSDDLIHHHHDYHHILHH-HHHQNHHPHSH 578
H HD L Q D H H H HH H H + H H+H
Sbjct: 31 HDDLHDDL-QEDFHGHSHRHSHEDFHHGHSHAHGHGHTH 68
>gi|117553608 solute carrier family 39, member 7 [Homo sapiens]
Length = 469
Score = 95.1 bits (235), Expect = 2e-19
Identities = 58/171 (33%), Positives = 92/171 (53%), Gaps = 14/171 (8%)
Query: 583 SREELKDAGVATLAWMVIMGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAVFCHELPHELG 642
+ EE + + ++ + D HNF+DGLAIGA+F G G+ T++ V HE+PHE+G
Sbjct: 306 AEEEKRGLDLRVSGYLNLAADLAHNFTDGLAIGASFRGGRGLGILTTMTVLLHEVPHEVG 365
Query: 643 DFAVLLKAGMTVKQAVLYNALSAMLAYLGMATGIFIGHYAENVSM-------WIFALTAG 695
DFA+L+++G + KQA+ L+A+ A G A + A + W+ TAG
Sbjct: 366 DFAILVQSGCSKKQAMRLQLLTAVGALAGTACALLTEGGAVGSEIAGGAGPGWVLPFTAG 425
Query: 696 LFMYVALVDMVPEMLHNDASDHGCSRWGYFFLQNAGMLLGFGIMLLISIFE 746
F+YVA V ++PE+L + L+ G+L G +M+LI+ E
Sbjct: 426 GFIYVATVSVLPELLREASPLQS-------LLEVLGLLGGVIMMVLIAHLE 469
Score = 46.2 bits (108), Expect = 1e-04
Identities = 30/85 (35%), Positives = 43/85 (50%), Gaps = 5/85 (5%)
Query: 325 WVGGFIAISIISFLSLLGVILVPL-MNRVFFKFLLSFLVALAVGTLSGDAFLHLLPHSHA 383
W A +IS + L+P+ N + LL L++ A G L GDAFLHL+PH+
Sbjct: 135 WAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLSFASGGLLGDAFLHLIPHALE 194
Query: 384 SHHHSHSHEEPA---MEMKRGPLFS 405
H H H+ E+P +GP+ S
Sbjct: 195 PHSH-HTLEQPGHGHSHSGQGPILS 218
Score = 44.3 bits (103), Expect = 4e-04
Identities = 22/66 (33%), Positives = 30/66 (45%), Gaps = 5/66 (7%)
Query: 91 HIHHD--HDHHSDHEH-HSDHERHSDHEHHSDHE--HHSDHDHHSHHNHAASGKNKRKAL 145
H H H H DH+H HS + H H H HE +H H H H+H G++ +
Sbjct: 66 HTHESIWHGHTHDHDHGHSHEDLHHGHSHGYSHESLYHRGHGHDHEHSHGGYGESGAPGI 125
Query: 146 CPDHDS 151
D D+
Sbjct: 126 KQDLDA 131
Score = 40.0 bits (92), Expect = 0.008
Identities = 24/76 (31%), Positives = 31/76 (40%), Gaps = 3/76 (3%)
Query: 91 HIHHDHDHHSDHEHHSDHERHSD-HEHHSDHEH-HSDHDHHSHHNHAASGKN-KRKALCP 147
H H D H H H H S H H DH+H HS D H H+H S ++ +
Sbjct: 49 HSHEDFHHGHSHAHGHGHTHESIWHGHTHDHDHGHSHEDLHHGHSHGYSHESLYHRGHGH 108
Query: 148 DHDSDSSGKDPRNSQG 163
DH+ G + G
Sbjct: 109 DHEHSHGGYGESGAPG 124
Score = 39.3 bits (90), Expect = 0.014
Identities = 30/87 (34%), Positives = 40/87 (45%), Gaps = 8/87 (9%)
Query: 494 LRADSQEPSHFDSQQPAVLEEEEVMIAHAHPQEVYNEYVPRGCKNKCHSHFHDTLGQSDD 553
L D QE H S + + E+ +HAH +E + G H+H HD +D
Sbjct: 34 LHDDLQEDFHGHSHRHSH-EDFHHGHSHAHGHGHTHESIWHG-----HTHDHDHGHSHED 87
Query: 554 LIH-HHHDY-HHILHHHHHQNHHPHSH 578
L H H H Y H L+H H + H HSH
Sbjct: 88 LHHGHSHGYSHESLYHRGHGHDHEHSH 114
Score = 38.5 bits (88), Expect = 0.023
Identities = 21/51 (41%), Positives = 24/51 (47%), Gaps = 3/51 (5%)
Query: 541 HSHFHDTLGQSDDLIHHHHDYHHILHHHHHQNHHPHSHSQRYSREELKDAG 591
HSH H G + + I H H + H H H HH HSH YS E L G
Sbjct: 58 HSHAHGH-GHTHESIWHGHTHDHDHGHSHEDLHHGHSHG--YSHESLYHRG 105
Score = 35.0 bits (79), Expect = 0.26
Identities = 15/43 (34%), Positives = 16/43 (37%), Gaps = 2/43 (4%)
Query: 94 HDHDHHSDHE--HHSDHERHSDHEHHSDHEHHSDHDHHSHHNH 134
H H H HE HH H H H HDH H+H
Sbjct: 43 HGHSHRHSHEDFHHGHSHAHGHGHTHESIWHGHTHDHDHGHSH 85
Score = 34.3 bits (77), Expect = 0.44
Identities = 23/89 (25%), Positives = 32/89 (35%), Gaps = 11/89 (12%)
Query: 90 IHIHHDHDHHSDHEHHSDHERHSDHEHHSDHEHHSD---HDHHSHHNHAASGKNKRKALC 146
+H D H HS + H H H H H + H H H+H S ++
Sbjct: 34 LHDDLQEDFHGHSHRHSHEDFHHGHSHAHGHGHTHESIWHGHTHDHDHGHSHEDL----- 88
Query: 147 PDHDSDSSGKDPRNSQGKG-AHRPEHASG 174
H S G + +G H EH+ G
Sbjct: 89 --HHGHSHGYSHESLYHRGHGHDHEHSHG 115
Score = 31.6 bits (70), Expect = 2.8
Identities = 16/39 (41%), Positives = 18/39 (46%), Gaps = 2/39 (5%)
Query: 541 HSHFHDTLGQSDDLIHHHHDYHHILHH-HHHQNHHPHSH 578
H HD L Q D H H H HH H H + H H+H
Sbjct: 31 HDDLHDDL-QEDFHGHSHRHSHEDFHHGHSHAHGHGHTH 68
>gi|40255101 solute carrier family 39 (zinc transporter), member 13
isoform b [Homo sapiens]
Length = 364
Score = 80.9 bits (198), Expect = 4e-15
Identities = 40/119 (33%), Positives = 69/119 (57%), Gaps = 2/119 (1%)
Query: 597 WMVIMGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAVFCHELPHELGDFAVLLKAGMTVKQ 656
++ ++ + + NF+ GLA+ A+F GL T++A+ HE+PHE+GDFA+LL+AG
Sbjct: 219 YLNLLANTIDNFTHGLAVAASFLVSKKIGLLTTMAILLHEIPHEVGDFAILLRAGFDRWS 278
Query: 657 AVLYNALSAMLAYLGMATGIFI--GHYAENVSMWIFALTAGLFMYVALVDMVPEMLHND 713
A +A+ LG I E + W+ T+G F+Y+ALV+++P++L +
Sbjct: 279 AAKLQLSTALGGLLGAGFAICTQSPKGVEETAAWVLPFTSGGFLYIALVNVLPDLLEEE 337
Score = 32.3 bits (72), Expect = 1.7
Identities = 21/97 (21%), Positives = 45/97 (46%), Gaps = 5/97 (5%)
Query: 292 PAIINQIDARSCLIHTSEKKAEIPPKTYSLQIAWVGGFIAISIISFLSLLGVILVPLMNR 351
PA+ ++ A +C + E ++ + W+ + ++ + ++++PL
Sbjct: 35 PALRSRGTATACRLDNKESESWGALLSGERLDTWICSLLGSLMVGLSGVFPLLVIPLEMG 94
Query: 352 VFFK-----FLLSFLVALAVGTLSGDAFLHLLPHSHA 383
+ + L L++ A+G L G+ FLHLLP + A
Sbjct: 95 TMLRSEAGAWRLKQLLSFALGGLLGNVFLHLLPEAWA 131
>gi|190014617 solute carrier family 39 (zinc transporter), member 13
isoform a [Homo sapiens]
Length = 371
Score = 80.5 bits (197), Expect = 5e-15
Identities = 41/126 (32%), Positives = 70/126 (55%), Gaps = 9/126 (7%)
Query: 597 WMVIMGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAVFCHELPHELGDFAVLLKAGMTVKQ 656
++ ++ + + NF+ GLA+ A+F GL T++A+ HE+PHE+GDFA+LL+AG
Sbjct: 219 YLNLLANTIDNFTHGLAVAASFLVSKKIGLLTTMAILLHEIPHEVGDFAILLRAGFDRWS 278
Query: 657 AVLYNALSAMLAYLGMATGIF---------IGHYAENVSMWIFALTAGLFMYVALVDMVP 707
A +A+ LG I AE + W+ T+G F+Y+ALV+++P
Sbjct: 279 AAKLQLSTALGGLLGAGFAICTQSPKGVVGCSPAAEETAAWVLPFTSGGFLYIALVNVLP 338
Query: 708 EMLHND 713
++L +
Sbjct: 339 DLLEEE 344
Score = 32.3 bits (72), Expect = 1.7
Identities = 21/97 (21%), Positives = 45/97 (46%), Gaps = 5/97 (5%)
Query: 292 PAIINQIDARSCLIHTSEKKAEIPPKTYSLQIAWVGGFIAISIISFLSLLGVILVPLMNR 351
PA+ ++ A +C + E ++ + W+ + ++ + ++++PL
Sbjct: 35 PALRSRGTATACRLDNKESESWGALLSGERLDTWICSLLGSLMVGLSGVFPLLVIPLEMG 94
Query: 352 VFFK-----FLLSFLVALAVGTLSGDAFLHLLPHSHA 383
+ + L L++ A+G L G+ FLHLLP + A
Sbjct: 95 TMLRSEAGAWRLKQLLSFALGGLLGNVFLHLLPEAWA 131
>gi|68299795 chromodomain helicase DNA binding protein 1 [Homo
sapiens]
Length = 1710
Score = 55.8 bits (133), Expect = 1e-07
Identities = 33/98 (33%), Positives = 44/98 (44%), Gaps = 9/98 (9%)
Query: 85 DKIKRIHIHHDHDHHSDHEHHSDHERHSDHEHHSDHEHHSDHDHHSHHNHAASGKNKR-- 142
+K +++ H DH S+ E HSDH HSDH HSDH S + H S ++ R
Sbjct: 1602 EKHRKLDDHRSRDHRSNLEGSLKDRSHSDHRSHSDHRLHSDHRSSSEYTHHKSSRDYRYH 1661
Query: 143 KALCPDHDSDSSG-------KDPRNSQGKGAHRPEHAS 173
DH + SSG + P S+ H EH S
Sbjct: 1662 SDWQMDHRASSSGPRSPLDQRSPYGSRSPFEHSVEHKS 1699
Score = 38.1 bits (87), Expect = 0.030
Identities = 30/104 (28%), Positives = 43/104 (41%), Gaps = 8/104 (7%)
Query: 91 HIHHDHDHHSDHEHHSDHERHSD-----HEHHSDHEHHSDHDHHSHHNHAASGKNKRKAL 145
H+ HDHH D H D + SD + S+ + H D DH+ + S + K + L
Sbjct: 1549 HLTQYHDHHKDR-HQGDSYKKSDSRKRPYSSFSNGKDHRDWDHYKQDSRYYSDREKHRKL 1607
Query: 146 CPDHDSDSSGKDPRNSQGKGAHRPEHA-SGRRNVKDSVSASEVT 188
DH S + S +H + S R D S+SE T
Sbjct: 1608 -DDHRSRDHRSNLEGSLKDRSHSDHRSHSDHRLHSDHRSSSEYT 1650
>gi|40254928 solute carrier family 39 (zinc transporter), member 9
[Homo sapiens]
Length = 307
Score = 55.5 bits (132), Expect = 2e-07
Identities = 56/214 (26%), Positives = 95/214 (44%), Gaps = 34/214 (15%)
Query: 564 ILHHHHHQNHHPHSH----------------------SQRYSREELKDAGVATLAWMVIM 601
++H H H + H H S +S ++ + A + +
Sbjct: 91 VVHEHEHSHDHTQLHAYIGVSLVLGFVFMLLVDQIGNSHVHSTDDPEAARSSNSKITTTL 150
Query: 602 GDGLHNFSDGLAIGAAF-TEGLSSGLSTSVAVFCHELPHELGDFAVLLKAGMT---VKQA 657
G +H +DG+A+GAA T S L VA+ H+ P G + L+ AG+ +++
Sbjct: 151 GLVVHAAADGVALGAAASTSQTSVQLIVFVAIMLHKAPAAFGLVSFLMHAGLERNRIRKH 210
Query: 658 VLYNALSA----MLAYLGMATGIFIGHYAENVSMWIFALTAGLFMYVALVDMVPE---ML 710
+L AL+A M+ YLG++ N + +AG F+YVA V ++PE +
Sbjct: 211 LLVFALAAPVMSMVTYLGLSKSSKEALSEVNATGVAMLFSAGTFLYVATVHVLPEVGGIG 270
Query: 711 HNDASDHGCSRWGYFFLQNAGMLLGFGIMLLISI 744
H+ D R G L+ A ++LG I L++S+
Sbjct: 271 HSHKPDATGGR-GLSRLEVAALVLGCLIPLILSV 303
>gi|221316609 sperm-associated cation channel 1 [Homo sapiens]
Length = 780
Score = 53.5 bits (127), Expect = 7e-07
Identities = 17/40 (42%), Positives = 20/40 (50%)
Query: 93 HHDHDHHSDHEHHSDHERHSDHEHHSDHEHHSDHDHHSHH 132
+H DHH HH DH H+ H +H H H H H HH
Sbjct: 267 YHQGDHHPSEYHHGDHPHHTQHHYHQTHRHRDYHQHQDHH 306
Score = 47.8 bits (112), Expect = 4e-05
Identities = 16/41 (39%), Positives = 23/41 (56%), Gaps = 3/41 (7%)
Query: 97 DHHSDH---EHHSDHERHSDHEHHSDHEHHSDHDHHSHHNH 134
D+HS++ +HH H DH HH+ H +H H H +H H
Sbjct: 262 DYHSEYHQGDHHPSEYHHGDHPHHTQHHYHQTHRHRDYHQH 302
Score = 45.4 bits (106), Expect = 2e-04
Identities = 32/106 (30%), Positives = 49/106 (46%), Gaps = 9/106 (8%)
Query: 93 HHDHDHHSDHEHHSDHERHSDHEHHSDHEHHSDHDHHSHHNHAASGKNKRKALCPDHDSD 152
H DH HH+ H +H H RH D+ H DH H + H + H ++ S L H S
Sbjct: 279 HGDHPHHTQHHYHQTH-RHRDYHQHQDH-HGAYHSSYLHGDYVQS----TSQLSIPHTSR 332
Query: 153 SSGKD-PRNSQGKGAHRPEHASGRRNVKDSVSASEVTSTVYNTVSE 197
S D P + + P H + R S++ S +ST+ + V++
Sbjct: 333 SLIHDAPGPAASRTGVFPYHVAHPRGSAHSMTRS--SSTIRSRVTQ 376
Score = 39.7 bits (91), Expect = 0.010
Identities = 19/75 (25%), Positives = 27/75 (36%), Gaps = 29/75 (38%)
Query: 89 RIHIHHDHDHHSDHEH--------------------------HSDH---ERHSDHEHHSD 119
++H H HH H+H HS++ + H HH D
Sbjct: 222 QVHHHGRSRHHEAHQHGKSPHHGETISPHSSVGSYQRGISDYHSEYHQGDHHPSEYHHGD 281
Query: 120 HEHHSDHDHHSHHNH 134
H HH+ H +H H H
Sbjct: 282 HPHHTQHHYHQTHRH 296
Score = 39.7 bits (91), Expect = 0.010
Identities = 17/75 (22%), Positives = 28/75 (37%), Gaps = 18/75 (24%)
Query: 93 HHDHDHHSDHEHHSD------------------HERHSDHEHHSDHEHHSDHDHHSHHNH 134
HH+ H HH + H + +HH HH DH HH+ H++
Sbjct: 231 HHEAHQHGKSPHHGETISPHSSVGSYQRGISDYHSEYHQGDHHPSEYHHGDHPHHTQHHY 290
Query: 135 AASGKNKRKALCPDH 149
+ +++ DH
Sbjct: 291 HQTHRHRDYHQHQDH 305
Score = 38.5 bits (88), Expect = 0.023
Identities = 31/139 (22%), Positives = 56/139 (40%), Gaps = 9/139 (6%)
Query: 523 HPQEVYNEYVPRGCKNKCHSHFHDTLGQSDDLIHHHHDYHHILHHHHHQNHHPHSHSQRY 582
H E + + G + S +H Q D HH +YHH H HH Q+H+ +H R
Sbjct: 242 HHGETISPHSSVGSYQRGISDYHSEYHQGD---HHPSEYHHGDHPHHTQHHYHQTHRHRD 298
Query: 583 SREELKDAGVATLAWMVIMGDGLHNFSDGLAI---GAAFTEGLSSGLSTSVAVFCHELPH 639
+ G ++ + GD + + S L+I + ++ VF + + H
Sbjct: 299 YHQHQDHHGAYHSSY--LHGDYVQSTSQ-LSIPHTSRSLIHDAPGPAASRTGVFPYHVAH 355
Query: 640 ELGDFAVLLKAGMTVKQAV 658
G + ++ T++ V
Sbjct: 356 PRGSAHSMTRSSSTIRSRV 374
Score = 33.9 bits (76), Expect = 0.57
Identities = 18/69 (26%), Positives = 24/69 (34%), Gaps = 4/69 (5%)
Query: 521 HAHPQEVYNEYVPRGCKNKCHSHFHDTLGQSDDLIHHHHDYHHILHH---HHHQNHHPHS 577
H Y+P G S H L H +H + H HHHQ HH H
Sbjct: 169 HGEASHHGGSYLPHGPNPYSESFHHSEASHLSGLQHDESQHHQVPHRGWPHHHQVHH-HG 227
Query: 578 HSQRYSREE 586
S+ + +
Sbjct: 228 RSRHHEAHQ 236
Score = 33.5 bits (75), Expect = 0.75
Identities = 19/81 (23%), Positives = 31/81 (38%), Gaps = 13/81 (16%)
Query: 91 HIHHDHDHHSDHEHHSDHERHSDHEHHSDHEHHSDH----DHHSHHNHAASGKNKRKALC 146
++ H + +S+ HHS+ S +H H H HH H+H S
Sbjct: 179 YLPHGPNPYSESFHHSEASHLSGLQHDESQHHQVPHRGWPHHHQVHHHGRS--------- 229
Query: 147 PDHDSDSSGKDPRNSQGKGAH 167
H++ GK P + + H
Sbjct: 230 RHHEAHQHGKSPHHGETISPH 250
Score = 33.1 bits (74), Expect = 0.98
Identities = 23/85 (27%), Positives = 31/85 (36%), Gaps = 5/85 (5%)
Query: 98 HHSDHEHHSDHERHSDHEHHSDHEHH----SDHDHHSHHNHAASGKNKRKALCPDHDSDS 153
H+ H H H+R H + H S H H SHH+ A + + S
Sbjct: 42 HYELHHHGVPHQRGESHHPPEFQDFHDQALSSHVHQSHHHSEARNHGRAHGPTGFGLAPS 101
Query: 154 SGKDP-RNSQGKGAHRPEHASGRRN 177
G P S G+ H GRR+
Sbjct: 102 QGAVPSHRSYGEDYHDELQRDGRRH 126
Score = 32.7 bits (73), Expect = 1.3
Identities = 22/80 (27%), Positives = 30/80 (37%), Gaps = 4/80 (5%)
Query: 93 HHDHDHHSDHEHHSDHERHSDHEHHSDHEH-HSDHDHHSHHNHAASGKNKRKALCPDHDS 151
HH H HH H H HH H+H S H + H++ G +R D+ S
Sbjct: 209 HHQVPHRGWPHHHQVHH-HGRSRHHEAHQHGKSPHHGETISPHSSVGSYQRG--ISDYHS 265
Query: 152 DSSGKDPRNSQGKGAHRPEH 171
+ D S+ P H
Sbjct: 266 EYHQGDHHPSEYHHGDHPHH 285
Score = 31.6 bits (70), Expect = 2.8
Identities = 16/60 (26%), Positives = 26/60 (43%), Gaps = 2/60 (3%)
Query: 532 VPRGCKNKCHSHFHDTLGQSDDLIHHHHDYHHILHHHHHQNHH--PHSHSQRYSREELKD 589
VP +N+ ++ D +S HH H HH+ +HH PH + + E +D
Sbjct: 6 VPEKAQNEADTNNADRFFRSHSSPPHHRPGHSRALHHYELHHHGVPHQRGESHHPPEFQD 65
>gi|148762982 hypothetical protein LOC387640 [Homo sapiens]
Length = 908
Score = 50.8 bits (120), Expect = 5e-06
Identities = 29/120 (24%), Positives = 46/120 (38%), Gaps = 13/120 (10%)
Query: 93 HHDHDHHSDHEHHSDHERHSDHEHHSDHEHH-------------SDHDHHSHHNHAASGK 139
HH H HH H HH + HH H H SD + S+ +HAA+
Sbjct: 337 HHHHHHHHHHHHHHHRAQPPQQSHHPPHHHRPQPHLGSFPESCSSDSESSSYSDHAANDS 396
Query: 140 NKRKALCPDHDSDSSGKDPRNSQGKGAHRPEHASGRRNVKDSVSASEVTSTVYNTVSEGT 199
+ +L +S SS ++ + + E + VS+ E S+ + S G+
Sbjct: 397 DFGSSLSSSSNSVSSEEEEEEGEEEEEEEEEEGGSGASDSSEVSSEEEDSSTESDSSSGS 456
Score = 43.1 bits (100), Expect = 0.001
Identities = 19/44 (43%), Positives = 21/44 (47%), Gaps = 5/44 (11%)
Query: 540 CHSHFHDTLGQSDDLIHHHHDYHHILHHHH-----HQNHHPHSH 578
C FH G HHHH +HH HHHH Q+HHP H
Sbjct: 322 CLERFHLVNGFCPPPHHHHHHHHHHHHHHHRAQPPQQSHHPPHH 365
Score = 37.0 bits (84), Expect = 0.068
Identities = 14/35 (40%), Positives = 17/35 (48%), Gaps = 12/35 (34%)
Query: 556 HHHHDYHHILHHHHHQ------------NHHPHSH 578
HHHH +HH HHHHH+ +H P H
Sbjct: 337 HHHHHHHHHHHHHHHRAQPPQQSHHPPHHHRPQPH 371
Score = 33.1 bits (74), Expect = 0.98
Identities = 10/16 (62%), Positives = 11/16 (68%)
Query: 566 HHHHHQNHHPHSHSQR 581
HHHHH +HH H H R
Sbjct: 337 HHHHHHHHHHHHHHHR 352
Score = 32.7 bits (73), Expect = 1.3
Identities = 14/43 (32%), Positives = 16/43 (37%), Gaps = 9/43 (20%)
Query: 536 CKNKCHSHFHDTLGQSDDLIHHHHDYHHILHHHHHQNHHPHSH 578
C H H H HHHH +HH +H PH H
Sbjct: 333 CPPPHHHHHHH---------HHHHHHHHRAQPPQQSHHPPHHH 366
>gi|229577422 solute carrier family 39, member 11 isoform 1 [Homo
sapiens]
Length = 342
Score = 49.7 bits (117), Expect = 1e-05
Identities = 39/154 (25%), Positives = 66/154 (42%), Gaps = 17/154 (11%)
Query: 598 MVIMGDGLHNFSDGLAIGAAF-------TEGLSSGLSTSVAVFCHELPHELGDFAVLLKA 650
++I+ +HN +GLA+G F + S + ++ + P L L A
Sbjct: 196 LLILAITIHNVPEGLAVGVGFGAIEKTASATFESARNLAIGIGIQNFPEGLAVSLPLRGA 255
Query: 651 GMTVKQAVLYNALSAMLAYLGMATGIFIGHYAENVSMWIFALTAGLFMYVALVDMVPEML 710
G + +A Y LS M+ L G F AE + + A AG +YV + D++PE
Sbjct: 256 GFSTWRAFWYGQLSGMVEPLAGVFGAFAVVLAEPILPYALAFAAGAMVYVVMDDIIPEA- 314
Query: 711 HNDASDHGCSRWGYFFLQNAGMLLGFGIMLLISI 744
S +G L + +LGF +M+ + +
Sbjct: 315 --QISGNG-------KLASWASILGFVVMMSLDV 339
>gi|229577418 solute carrier family 39, member 11 isoform 2 [Homo
sapiens]
Length = 335
Score = 49.7 bits (117), Expect = 1e-05
Identities = 39/154 (25%), Positives = 66/154 (42%), Gaps = 17/154 (11%)
Query: 598 MVIMGDGLHNFSDGLAIGAAF-------TEGLSSGLSTSVAVFCHELPHELGDFAVLLKA 650
++I+ +HN +GLA+G F + S + ++ + P L L A
Sbjct: 189 LLILAITIHNVPEGLAVGVGFGAIEKTASATFESARNLAIGIGIQNFPEGLAVSLPLRGA 248
Query: 651 GMTVKQAVLYNALSAMLAYLGMATGIFIGHYAENVSMWIFALTAGLFMYVALVDMVPEML 710
G + +A Y LS M+ L G F AE + + A AG +YV + D++PE
Sbjct: 249 GFSTWRAFWYGQLSGMVEPLAGVFGAFAVVLAEPILPYALAFAAGAMVYVVMDDIIPEA- 307
Query: 711 HNDASDHGCSRWGYFFLQNAGMLLGFGIMLLISI 744
S +G L + +LGF +M+ + +
Sbjct: 308 --QISGNG-------KLASWASILGFVVMMSLDV 332
>gi|32698730 nuclear fragile X mental retardation protein
interacting protein 2 [Homo sapiens]
Length = 695
Score = 48.1 bits (113), Expect = 3e-05
Identities = 29/124 (23%), Positives = 49/124 (39%), Gaps = 15/124 (12%)
Query: 94 HDHDHHSDHEHHSDHERHSDHEHHSDHEHHSDHDHHSHHN--------HAASGKNKRKAL 145
H H HH H H ++ H HH +HS + HH HH+ H A G K +
Sbjct: 12 HHHSHHHPHHHPQQQQQQPHHHHHYYFYNHSHNHHHHHHHQQPHQYLQHGAEGSPKAQPK 71
Query: 146 CPDHDS----DSSGKDPRNSQGKGAHRPEHASGRRNVK-DSVSASEVTSTVYNTVSEGTH 200
H+ + P+ G G +G R + ++S+ E T+ + ++
Sbjct: 72 PLKHEQKHTLQQHQETPKKKTGYGELNGN--AGEREISLKNLSSDEATNPISRVLNGNQQ 129
Query: 201 FLET 204
++T
Sbjct: 130 VVDT 133
Score = 43.5 bits (101), Expect = 7e-04
Identities = 17/50 (34%), Positives = 23/50 (46%)
Query: 533 PRGCKNKCHSHFHDTLGQSDDLIHHHHDYHHILHHHHHQNHHPHSHSQRY 582
P+ + H H H Q HHHH Y+ H H+H +HH H +Y
Sbjct: 8 PQPQHHHSHHHPHHHPQQQQQQPHHHHHYYFYNHSHNHHHHHHHQQPHQY 57
Score = 42.0 bits (97), Expect = 0.002
Identities = 15/44 (34%), Positives = 22/44 (50%), Gaps = 5/44 (11%)
Query: 91 HIHHDHDHHSDHEHHSDHERHSDHEHHSDHEHHSDHDHHSHHNH 134
H H H H HH ++ H HH + ++ H+HH HH+H
Sbjct: 13 HHSHHHPH-----HHPQQQQQQPHHHHHYYFYNHSHNHHHHHHH 51
Score = 31.6 bits (70), Expect = 2.8
Identities = 9/18 (50%), Positives = 13/18 (72%)
Query: 568 HHHQNHHPHSHSQRYSRE 585
HHH +HHPH H Q+ ++
Sbjct: 12 HHHSHHHPHHHPQQQQQQ 29
>gi|4504489 histidine-rich glycoprotein precursor [Homo sapiens]
Length = 525
Score = 47.8 bits (112), Expect = 4e-05
Identities = 25/78 (32%), Positives = 31/78 (39%), Gaps = 6/78 (7%)
Query: 91 HIHHDHDHHSDHEHHSDHERHSDHEH-HSDHEHHSDHDHHSHHNHAASGKNKRKALCPDH 149
H H H HH H +H+ H H H H H HH H HH H +H + C D
Sbjct: 357 HEQHPHGHHPHAHHPHEHDTHRQHPHGHHPHGHHP-HGHHPHGHH----PHGHHPHCHDF 411
Query: 150 DSDSSGKDPRNSQGKGAH 167
P ++QG H
Sbjct: 412 QDYGPCDPPPHNQGHCCH 429
Score = 43.1 bits (100), Expect = 0.001
Identities = 21/58 (36%), Positives = 26/58 (44%), Gaps = 8/58 (13%)
Query: 521 HAHPQEVYNEYVPRGCKNKCHSHFHDTLGQSDDLIHHHHDYHHILHHHHHQNHHPHSH 578
H+H Q + + + H H HDT Q H HH + H H HH HHPH H
Sbjct: 355 HSHEQHPHGHH-----PHAHHPHEHDTHRQHP---HGHHPHGHHPHGHHPHGHHPHGH 404
Score = 37.0 bits (84), Expect = 0.068
Identities = 19/55 (34%), Positives = 23/55 (41%), Gaps = 8/55 (14%)
Query: 532 VPRGCKNKCHSHF-------HDTLGQSDDLI-HHHHDYHHILHHHHHQNHHPHSH 578
+P C + H+ F H S DL H HH + H HH HHPH H
Sbjct: 320 LPMSCSSCQHATFGTNGAQRHSHNNNSSDLHPHKHHSHEQHPHGHHPHAHHPHEH 374
Score = 35.0 bits (79), Expect = 0.26
Identities = 16/50 (32%), Positives = 18/50 (36%), Gaps = 9/50 (18%)
Query: 91 HIHHDHDHHSDHEHHSDHERHSDHEHHSDHE---------HHSDHDHHSH 131
H HH H HH H H H H H D + H+ H H H
Sbjct: 382 HGHHPHGHHPHGHHPHGHHPHGHHPHCHDFQDYGPCDPPPHNQGHCCHGH 431
Score = 34.7 bits (78), Expect = 0.34
Identities = 21/67 (31%), Positives = 28/67 (41%), Gaps = 14/67 (20%)
Query: 109 ERHSDHEHHSD---HEHHSDHDH-HSHHNHAASGKNKRKALCPDHDSDSSGKDPRNSQGK 164
+RHS + + SD H+HHS H H HH HA H+ D+ + P
Sbjct: 338 QRHSHNNNSSDLHPHKHHSHEQHPHGHHPHAHH----------PHEHDTHRQHPHGHHPH 387
Query: 165 GAHRPEH 171
G H H
Sbjct: 388 GHHPHGH 394
Score = 32.0 bits (71), Expect = 2.2
Identities = 19/70 (27%), Positives = 23/70 (32%), Gaps = 4/70 (5%)
Query: 103 EHHSDHERHSDHEHHSDHEHHS-DHDHHSHHNHAASGKNKRKALCPDHDSDSSGKDPRNS 161
+ HS + SD H H H H HH H +H R+ H G P
Sbjct: 338 QRHSHNNNSSDLHPHKHHSHEQHPHGHHPHAHHPHEHDTHRQ---HPHGHHPHGHHPHGH 394
Query: 162 QGKGAHRPEH 171
G H H
Sbjct: 395 HPHGHHPHGH 404
Score = 31.2 bits (69), Expect = 3.7
Identities = 16/43 (37%), Positives = 17/43 (39%), Gaps = 2/43 (4%)
Query: 538 NKCHSHFHDTLGQSDDLIHHHHDYHHILHHHHHQNH--HPHSH 578
+K HSH G H H H H H H H HPH H
Sbjct: 352 HKHHSHEQHPHGHHPHAHHPHEHDTHRQHPHGHHPHGHHPHGH 394
Score = 30.8 bits (68), Expect = 4.9
Identities = 18/53 (33%), Positives = 21/53 (39%), Gaps = 3/53 (5%)
Query: 89 RIHIHHDHDH-HSDHEHH-SDHERHSDHEHHSDHEHHSDHDHHSHH-NHAASG 138
R H H H H H H HH H H H H D + + D H+ H G
Sbjct: 378 RQHPHGHHPHGHHPHGHHPHGHHPHGHHPHCHDFQDYGPCDPPPHNQGHCCHG 430
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.133 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,974,509
Number of Sequences: 37866
Number of extensions: 1357895
Number of successful extensions: 14489
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 146
Number of HSP's successfully gapped in prelim test: 108
Number of HSP's that attempted gapping in prelim test: 7486
Number of HSP's gapped (non-prelim): 3808
length of query: 755
length of database: 18,247,518
effective HSP length: 110
effective length of query: 645
effective length of database: 14,082,258
effective search space: 9083056410
effective search space used: 9083056410
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.