Guide to the Human Genome
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Search of human proteins with 149944551

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|149944551 defensin, beta 131 [Homo sapiens]
         (70 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|149944551 defensin, beta 131 [Homo sapiens]                        154   2e-38
gi|169173154 PREDICTED: hypothetical protein [Homo sapiens]           150   2e-37
gi|169172390 PREDICTED: similar to defensin, beta 131 [Homo sapi...   150   2e-37
gi|169172906 PREDICTED: similar to defensin, beta 131 [Homo sapi...   146   3e-36
gi|169202989 PREDICTED: similar to defensin, beta 131 [Homo sapi...   146   4e-36
gi|169203494 PREDICTED: similar to defensin, beta 131 [Homo sapi...   146   4e-36
gi|169202282 PREDICTED: similar to defensin, beta 131 [Homo sapi...   146   4e-36
gi|239743495 PREDICTED: hypothetical protein XP_002342880 [Homo ...   145   5e-36
gi|82734219 beta-defensin 114 [Homo sapiens]                           38   0.002
gi|18250304 beta defensin 129 precursor [Homo sapiens]                 34   0.028
gi|22748611 defensin, beta 106A precursor [Homo sapiens]               33   0.037
gi|103485143 defensin, beta 106B precursor [Homo sapiens]              33   0.037
gi|23503331 defensin, beta 123 precursor [Homo sapiens]                33   0.063
gi|103485139 defensin, beta 104A precursor [Homo sapiens]              30   0.31 
gi|103485137 defensin, beta 104B precursor [Homo sapiens]              30   0.31 
gi|16905373 beta-defensin 118 [Homo sapiens]                           29   0.70 
gi|116517226 beta-defensin 135 [Homo sapiens]                          28   1.2  
gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]                28   2.0  
gi|21040279 defensin, beta 127 preproprotein [Homo sapiens]            27   4.5  
gi|82734223 beta-defensin 124 [Homo sapiens]                           26   7.7  
gi|23503329 defensin, beta 119 isoform c precursor [Homo sapiens]      26   7.7  

>gi|149944551 defensin, beta 131 [Homo sapiens]
          Length = 70

 Score =  154 bits (388), Expect = 2e-38
 Identities = 70/70 (100%), Positives = 70/70 (100%)

Query: 1  MRVLFFVFGVLSLMFTVPPARSFISNDECPSEYYHCRLKCNADEHAIRYCADFSICCKLK 60
          MRVLFFVFGVLSLMFTVPPARSFISNDECPSEYYHCRLKCNADEHAIRYCADFSICCKLK
Sbjct: 1  MRVLFFVFGVLSLMFTVPPARSFISNDECPSEYYHCRLKCNADEHAIRYCADFSICCKLK 60

Query: 61 IIEIDGQKKW 70
          IIEIDGQKKW
Sbjct: 61 IIEIDGQKKW 70


>gi|169173154 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 70

 Score =  150 bits (380), Expect = 2e-37
 Identities = 69/70 (98%), Positives = 69/70 (98%)

Query: 1  MRVLFFVFGVLSLMFTVPPARSFISNDECPSEYYHCRLKCNADEHAIRYCADFSICCKLK 60
          MRVLFFVFGVLSLM TVPPARSFISNDECPSEYYHCRLKCNADEHAIRYCADFSICCKLK
Sbjct: 1  MRVLFFVFGVLSLMSTVPPARSFISNDECPSEYYHCRLKCNADEHAIRYCADFSICCKLK 60

Query: 61 IIEIDGQKKW 70
          IIEIDGQKKW
Sbjct: 61 IIEIDGQKKW 70


>gi|169172390 PREDICTED: similar to defensin, beta 131 [Homo
          sapiens]
          Length = 70

 Score =  150 bits (380), Expect = 2e-37
 Identities = 69/70 (98%), Positives = 69/70 (98%)

Query: 1  MRVLFFVFGVLSLMFTVPPARSFISNDECPSEYYHCRLKCNADEHAIRYCADFSICCKLK 60
          MRVLFFVFGVLSLM TVPPARSFISNDECPSEYYHCRLKCNADEHAIRYCADFSICCKLK
Sbjct: 1  MRVLFFVFGVLSLMSTVPPARSFISNDECPSEYYHCRLKCNADEHAIRYCADFSICCKLK 60

Query: 61 IIEIDGQKKW 70
          IIEIDGQKKW
Sbjct: 61 IIEIDGQKKW 70


>gi|169172906 PREDICTED: similar to defensin, beta 131 [Homo
          sapiens]
          Length = 70

 Score =  146 bits (369), Expect = 3e-36
 Identities = 67/70 (95%), Positives = 67/70 (95%)

Query: 1  MRVLFFVFGVLSLMFTVPPARSFISNDECPSEYYHCRLKCNADEHAIRYCADFSICCKLK 60
          MRVLFFVFGVLSLM TVPP RSFISNDECPSEYYHCRLKCNADEHAI YCADFSICCKLK
Sbjct: 1  MRVLFFVFGVLSLMSTVPPRRSFISNDECPSEYYHCRLKCNADEHAITYCADFSICCKLK 60

Query: 61 IIEIDGQKKW 70
          IIEIDGQKKW
Sbjct: 61 IIEIDGQKKW 70


>gi|169202989 PREDICTED: similar to defensin, beta 131 [Homo
          sapiens]
          Length = 70

 Score =  146 bits (368), Expect = 4e-36
 Identities = 66/70 (94%), Positives = 67/70 (95%)

Query: 1  MRVLFFVFGVLSLMFTVPPARSFISNDECPSEYYHCRLKCNADEHAIRYCADFSICCKLK 60
          MRVLFFVFGVLSLM TVPP RSF SNDECPSEYYHCRLKCNADEHAIRYCADFSICCKLK
Sbjct: 1  MRVLFFVFGVLSLMSTVPPTRSFTSNDECPSEYYHCRLKCNADEHAIRYCADFSICCKLK 60

Query: 61 IIEIDGQKKW 70
          II+IDGQKKW
Sbjct: 61 IIQIDGQKKW 70


>gi|169203494 PREDICTED: similar to defensin, beta 131 [Homo
          sapiens]
          Length = 70

 Score =  146 bits (368), Expect = 4e-36
 Identities = 66/70 (94%), Positives = 67/70 (95%)

Query: 1  MRVLFFVFGVLSLMFTVPPARSFISNDECPSEYYHCRLKCNADEHAIRYCADFSICCKLK 60
          MRVLFFVFGVLSLM TVPP RSF SNDECPSEYYHCRLKCNADEHAIRYCADFSICCKLK
Sbjct: 1  MRVLFFVFGVLSLMSTVPPTRSFTSNDECPSEYYHCRLKCNADEHAIRYCADFSICCKLK 60

Query: 61 IIEIDGQKKW 70
          II+IDGQKKW
Sbjct: 61 IIQIDGQKKW 70


>gi|169202282 PREDICTED: similar to defensin, beta 131 [Homo
          sapiens]
          Length = 70

 Score =  146 bits (368), Expect = 4e-36
 Identities = 66/70 (94%), Positives = 67/70 (95%)

Query: 1  MRVLFFVFGVLSLMFTVPPARSFISNDECPSEYYHCRLKCNADEHAIRYCADFSICCKLK 60
          MRVLFFVFGVLSLM TVPP RSF SNDECPSEYYHCRLKCNADEHAIRYCADFSICCKLK
Sbjct: 1  MRVLFFVFGVLSLMSTVPPTRSFTSNDECPSEYYHCRLKCNADEHAIRYCADFSICCKLK 60

Query: 61 IIEIDGQKKW 70
          II+IDGQKKW
Sbjct: 61 IIQIDGQKKW 70


>gi|239743495 PREDICTED: hypothetical protein XP_002342880 [Homo
          sapiens]
          Length = 70

 Score =  145 bits (367), Expect = 5e-36
 Identities = 67/70 (95%), Positives = 67/70 (95%)

Query: 1  MRVLFFVFGVLSLMFTVPPARSFISNDECPSEYYHCRLKCNADEHAIRYCADFSICCKLK 60
          MRVLFFVFGVLSLM TVPPARSFISNDECPSEYYHCRLKCNADEH IRYCA FSICCKLK
Sbjct: 1  MRVLFFVFGVLSLMSTVPPARSFISNDECPSEYYHCRLKCNADEHVIRYCAYFSICCKLK 60

Query: 61 IIEIDGQKKW 70
          IIEIDGQKKW
Sbjct: 61 IIEIDGQKKW 70


>gi|82734219 beta-defensin 114 [Homo sapiens]
          Length = 69

 Score = 38.1 bits (87), Expect = 0.002
 Identities = 18/66 (27%), Positives = 31/66 (46%), Gaps = 1/66 (1%)

Query: 1  MRVLFFVFGVLSLMFTVPPARSFISNDECPSEYYHCRLKCNADEHAIRYCA-DFSICCKL 59
          MR+ +++  +  + F +P   + ++ D C   Y  C+  C   E  I  C+    ICC  
Sbjct: 1  MRIFYYLHFLCYVTFILPATCTLVNADRCTKRYGRCKRDCLESEKQIDICSLPRKICCTE 60

Query: 60 KIIEID 65
          K+ E D
Sbjct: 61 KLYEED 66


>gi|18250304 beta defensin 129 precursor [Homo sapiens]
          Length = 183

 Score = 33.9 bits (76), Expect = 0.028
 Identities = 20/64 (31%), Positives = 29/64 (45%), Gaps = 2/64 (3%)

Query: 1  MRVLFFVFGVLSLMFTVPPARSFISNDECPSEYYHCRLKCNADEHAIRYCADFSICCKLK 60
          M++LF +F  L L + V     FI    C      CR  CN DE  I+ C     C   K
Sbjct: 1  MKLLFPIFASLMLQYQVNT--EFIGLRRCLMGLGRCRDHCNVDEKEIQKCKMKKCCVGPK 58

Query: 61 IIEI 64
          ++++
Sbjct: 59 VVKL 62


>gi|22748611 defensin, beta 106A precursor [Homo sapiens]
          Length = 65

 Score = 33.5 bits (75), Expect = 0.037
 Identities = 17/58 (29%), Positives = 27/58 (46%), Gaps = 3/58 (5%)

Query: 1  MRVLFFVFGVLSLMFTVPPARSFISNDECPSEYYHCRLKCNADEHAIRYCADFSICCK 58
          MR   F+F VL   F + PA++   +++C      C+  C  +E  I  C     CC+
Sbjct: 1  MRTFLFLFAVL---FFLTPAKNAFFDEKCNKLKGTCKNNCGKNEELIALCQKSLKCCR 55


>gi|103485143 defensin, beta 106B precursor [Homo sapiens]
          Length = 65

 Score = 33.5 bits (75), Expect = 0.037
 Identities = 17/58 (29%), Positives = 27/58 (46%), Gaps = 3/58 (5%)

Query: 1  MRVLFFVFGVLSLMFTVPPARSFISNDECPSEYYHCRLKCNADEHAIRYCADFSICCK 58
          MR   F+F VL   F + PA++   +++C      C+  C  +E  I  C     CC+
Sbjct: 1  MRTFLFLFAVL---FFLTPAKNAFFDEKCNKLKGTCKNNCGKNEELIALCQKSLKCCR 55


>gi|23503331 defensin, beta 123 precursor [Homo sapiens]
          Length = 67

 Score = 32.7 bits (73), Expect = 0.063
 Identities = 16/57 (28%), Positives = 25/57 (43%), Gaps = 4/57 (7%)

Query: 1  MRVLFFVFGVLSLMFTVPPARSFISNDECPSEYYHCRLKCNADEHAIRYCADFSICC 57
          M++L     VL L+  + P         C + Y  CR +C+  E    YC +  +CC
Sbjct: 1  MKLLLLTLTVLLLLSQLTPG----GTQRCWNLYGKCRYRCSKKERVYVYCINNKMCC 53


>gi|103485139 defensin, beta 104A precursor [Homo sapiens]
          Length = 72

 Score = 30.4 bits (67), Expect = 0.31
 Identities = 18/61 (29%), Positives = 26/61 (42%), Gaps = 1/61 (1%)

Query: 1  MRVLFFVFGVLSLMFTVPPARSFISNDE-CPSEYYHCRLKCNADEHAIRYCADFSICCKL 59
          M+ L  +  +  L++   P RS    D  C      CR KC + E+ I  C +   CC  
Sbjct: 1  MQRLVLLLAISLLLYQDLPVRSEFELDRICGYGTARCRKKCRSQEYRIGRCPNTYACCLR 60

Query: 60 K 60
          K
Sbjct: 61 K 61


>gi|103485137 defensin, beta 104B precursor [Homo sapiens]
          Length = 72

 Score = 30.4 bits (67), Expect = 0.31
 Identities = 18/61 (29%), Positives = 26/61 (42%), Gaps = 1/61 (1%)

Query: 1  MRVLFFVFGVLSLMFTVPPARSFISNDE-CPSEYYHCRLKCNADEHAIRYCADFSICCKL 59
          M+ L  +  +  L++   P RS    D  C      CR KC + E+ I  C +   CC  
Sbjct: 1  MQRLVLLLAISLLLYQDLPVRSEFELDRICGYGTARCRKKCRSQEYRIGRCPNTYACCLR 60

Query: 60 K 60
          K
Sbjct: 61 K 61


>gi|16905373 beta-defensin 118 [Homo sapiens]
          Length = 123

 Score = 29.3 bits (64), Expect = 0.70
 Identities = 17/57 (29%), Positives = 25/57 (43%), Gaps = 2/57 (3%)

Query: 1  MRVLFFVFGVLSLMFTVPPARSFISNDECPSEYYHCRLKCNADEHAIRYCADFSICC 57
          M++L     +L L+  V PA S     +C +   HCR +C   E     C +   CC
Sbjct: 1  MKLLLLALPMLVLLPQVIPAYS--GEKKCWNRSGHCRKQCKDGEAVKDTCKNLRACC 55


>gi|116517226 beta-defensin 135 [Homo sapiens]
          Length = 77

 Score = 28.5 bits (62), Expect = 1.2
 Identities = 20/62 (32%), Positives = 26/62 (41%), Gaps = 6/62 (9%)

Query: 2  RVLFFVFGVLSLMFTVPPARS----FISN--DECPSEYYHCRLKCNADEHAIRYCADFSI 55
          R +     VL+L+F VPP RS    +I      C      CR KC  +E     C    +
Sbjct: 4  RSVLLALVVLNLLFYVPPGRSGPNVYIQKIFASCWRLQGTCRPKCLKNEQYRILCDTIHL 63

Query: 56 CC 57
          CC
Sbjct: 64 CC 65


>gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]
          Length = 1541

 Score = 27.7 bits (60), Expect = 2.0
 Identities = 15/35 (42%), Positives = 17/35 (48%), Gaps = 10/35 (28%)

Query: 27  DECPSEYY--HCRLKCNADEHAIRYCADFSICCKL 59
           D CP  YY  HCR KCN        CA+   C +L
Sbjct: 596 DGCPKGYYGKHCRKKCN--------CANRGRCHRL 622


>gi|21040279 defensin, beta 127 preproprotein [Homo sapiens]
          Length = 99

 Score = 26.6 bits (57), Expect = 4.5
 Identities = 20/68 (29%), Positives = 30/68 (44%), Gaps = 7/68 (10%)

Query: 4  LFFVFGVLSLMFTVPPARSFISNDECPSEYY--HCRLKCNADEHAIRYCADFSICCKLKI 61
          LF +  +L  +F  P     +   +C + Y   HCR  C  +E     C +   CC L I
Sbjct: 3  LFMIIAIL--LFQKPTVTEQLK--KCWNNYVQGHCRKICRVNEVPEALCENGRYCC-LNI 57

Query: 62 IEIDGQKK 69
           E++  KK
Sbjct: 58 KELEACKK 65


>gi|82734223 beta-defensin 124 [Homo sapiens]
          Length = 71

 Score = 25.8 bits (55), Expect = 7.7
 Identities = 17/56 (30%), Positives = 24/56 (42%), Gaps = 3/56 (5%)

Query: 2  RVLFFVFGVLSLMFTVPPARSFISNDECPSEYYHCRLKCNADEHAIRYCADFSICC 57
          ++L F+  +L L   VP  RS      C      C+  C   E  +  C D S+CC
Sbjct: 3  QLLLFLVALLVLGH-VPSGRSEFKR--CWKGQGACQTYCTRQETYMHLCPDASLCC 55


>gi|23503329 defensin, beta 119 isoform c precursor [Homo sapiens]
          Length = 88

 Score = 25.8 bits (55), Expect = 7.7
 Identities = 10/23 (43%), Positives = 12/23 (52%)

Query: 35 HCRLKCNADEHAIRYCADFSICC 57
          HCRL C   E +I  C +   CC
Sbjct: 28 HCRLLCKDGEDSIIRCRNRKRCC 50


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.332    0.144    0.492 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 2,785,659
Number of Sequences: 37866
Number of extensions: 97364
Number of successful extensions: 249
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 232
Number of HSP's gapped (non-prelim): 21
length of query: 70
length of database: 18,247,518
effective HSP length: 43
effective length of query: 27
effective length of database: 16,619,280
effective search space: 448720560
effective search space used: 448720560
T: 11
A: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (22.0 bits)
S2: 55 (25.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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