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Search of human proteins with 149944526
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|149944526 additional sex combs like 3 [Homo sapiens]
(2248 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|149944526 additional sex combs like 3 [Homo sapiens] 4444 0.0
gi|153792780 additional sex combs like 2 [Homo sapiens] 358 4e-98
gi|29570782 additional sex combs like 1 [Homo sapiens] 335 3e-91
gi|91982772 mucin 17 [Homo sapiens] 131 9e-30
gi|239743293 PREDICTED: mucin 12 [Homo sapiens] 88 1e-16
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 84 2e-15
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ... 83 3e-15
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 81 1e-14
gi|167736355 mucin 4 isoform a [Homo sapiens] 80 3e-14
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f... 80 3e-14
gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ... 79 7e-14
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 77 1e-13
gi|83367077 mucin 16 [Homo sapiens] 77 2e-13
gi|239740773 PREDICTED: similar to diffuse panbronchiolitis crit... 77 2e-13
gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ... 76 4e-13
gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c ... 76 4e-13
gi|239754269 PREDICTED: hypothetical protein [Homo sapiens] 70 2e-11
gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo ... 70 2e-11
gi|239740674 PREDICTED: hypothetical protein [Homo sapiens] 70 2e-11
gi|239740645 PREDICTED: hypothetical protein [Homo sapiens] 70 2e-11
gi|113417486 PREDICTED: hypothetical protein [Homo sapiens] 70 3e-11
gi|239513940 PREDICTED: hypothetical protein [Homo sapiens] 70 3e-11
gi|169168665 PREDICTED: hypothetical protein [Homo sapiens] 69 4e-11
gi|239740898 PREDICTED: hypothetical protein [Homo sapiens] 69 4e-11
gi|239740777 PREDICTED: hypothetical protein [Homo sapiens] 69 4e-11
gi|239740724 PREDICTED: hypothetical protein [Homo sapiens] 69 4e-11
gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens] 67 2e-10
gi|239754668 PREDICTED: mucin 12 [Homo sapiens] 66 3e-10
gi|52485606 formin-like 2 [Homo sapiens] 66 3e-10
gi|11386183 WAS protein family, member 2 [Homo sapiens] 66 4e-10
>gi|149944526 additional sex combs like 3 [Homo sapiens]
Length = 2248
Score = 4444 bits (11526), Expect = 0.0
Identities = 2248/2248 (100%), Positives = 2248/2248 (100%)
Query: 1 MKDKRKKKDRTWAEAARLALEKHPNSPMTAKQILEVIQKEGLKETSGTSPLACLNAMLHT 60
MKDKRKKKDRTWAEAARLALEKHPNSPMTAKQILEVIQKEGLKETSGTSPLACLNAMLHT
Sbjct: 1 MKDKRKKKDRTWAEAARLALEKHPNSPMTAKQILEVIQKEGLKETSGTSPLACLNAMLHT 60
Query: 61 NTRIGDGTFFKIPGKSGLYALKKEESSCPADGTLDLVCESELDGTDMAEANAHGEENGVC 120
NTRIGDGTFFKIPGKSGLYALKKEESSCPADGTLDLVCESELDGTDMAEANAHGEENGVC
Sbjct: 61 NTRIGDGTFFKIPGKSGLYALKKEESSCPADGTLDLVCESELDGTDMAEANAHGEENGVC 120
Query: 121 SKQVTDEASSTRDSSLTNTAVQSKLVSSFQQHTKKALKQALRQQQKRRNGVSMMVNKTVP 180
SKQVTDEASSTRDSSLTNTAVQSKLVSSFQQHTKKALKQALRQQQKRRNGVSMMVNKTVP
Sbjct: 121 SKQVTDEASSTRDSSLTNTAVQSKLVSSFQQHTKKALKQALRQQQKRRNGVSMMVNKTVP 180
Query: 181 RVVLTPLKVSDEQSDSPSGSESKNGEADSSDKEMKHGQKSPTGKQTSQHLKRLKKSGLGH 240
RVVLTPLKVSDEQSDSPSGSESKNGEADSSDKEMKHGQKSPTGKQTSQHLKRLKKSGLGH
Sbjct: 181 RVVLTPLKVSDEQSDSPSGSESKNGEADSSDKEMKHGQKSPTGKQTSQHLKRLKKSGLGH 240
Query: 241 LKWTKAEDIDIETPGSILVNTNLRALINKHTFASLPQHFQQYLLLLLPEVDRQMGSDGIL 300
LKWTKAEDIDIETPGSILVNTNLRALINKHTFASLPQHFQQYLLLLLPEVDRQMGSDGIL
Sbjct: 241 LKWTKAEDIDIETPGSILVNTNLRALINKHTFASLPQHFQQYLLLLLPEVDRQMGSDGIL 300
Query: 301 RLSTSALNNEFFAYAAQGWKQRLAEGEFTPEMQLRIRQEIEKEKKTEPWKEKFFERFYGE 360
RLSTSALNNEFFAYAAQGWKQRLAEGEFTPEMQLRIRQEIEKEKKTEPWKEKFFERFYGE
Sbjct: 301 RLSTSALNNEFFAYAAQGWKQRLAEGEFTPEMQLRIRQEIEKEKKTEPWKEKFFERFYGE 360
Query: 361 KLGMSREESVKLTTGPNNAGAQSSSSCGTSGLPVSAQTALAEQQPKSMKSPASPEPGFCA 420
KLGMSREESVKLTTGPNNAGAQSSSSCGTSGLPVSAQTALAEQQPKSMKSPASPEPGFCA
Sbjct: 361 KLGMSREESVKLTTGPNNAGAQSSSSCGTSGLPVSAQTALAEQQPKSMKSPASPEPGFCA 420
Query: 421 TLCPMVEIPPKDIMAELESEDILIPEESVIQEEIAEEVETSICECQDENHKTIPEFSEEA 480
TLCPMVEIPPKDIMAELESEDILIPEESVIQEEIAEEVETSICECQDENHKTIPEFSEEA
Sbjct: 421 TLCPMVEIPPKDIMAELESEDILIPEESVIQEEIAEEVETSICECQDENHKTIPEFSEEA 480
Query: 481 ESLTNSHEEPQIAPPEDNLESCVMMNDVLETLPHIEVKIEGKSESPQEEMTVVIDQLEVC 540
ESLTNSHEEPQIAPPEDNLESCVMMNDVLETLPHIEVKIEGKSESPQEEMTVVIDQLEVC
Sbjct: 481 ESLTNSHEEPQIAPPEDNLESCVMMNDVLETLPHIEVKIEGKSESPQEEMTVVIDQLEVC 540
Query: 541 DSLIPSTSSMTHVSDTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMELQSDPEE 600
DSLIPSTSSMTHVSDTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMELQSDPEE
Sbjct: 541 DSLIPSTSSMTHVSDTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMELQSDPEE 600
Query: 601 QLSENACISETSFSSESPEGACTSLPSPGGETQSTSEESCTPASLETTFCSEVSSTENTD 660
QLSENACISETSFSSESPEGACTSLPSPGGETQSTSEESCTPASLETTFCSEVSSTENTD
Sbjct: 601 QLSENACISETSFSSESPEGACTSLPSPGGETQSTSEESCTPASLETTFCSEVSSTENTD 660
Query: 661 KYNQRNSTDENFHASLMSEISPISTSPEISEASLMSNLPLTSEASPVSNLPLTSETSPMS 720
KYNQRNSTDENFHASLMSEISPISTSPEISEASLMSNLPLTSEASPVSNLPLTSETSPMS
Sbjct: 661 KYNQRNSTDENFHASLMSEISPISTSPEISEASLMSNLPLTSEASPVSNLPLTSETSPMS 720
Query: 721 DLPLTSETSSVSSMLLTSETTFVSSLPLPSETSPISNSSINERMAHQQRKSPSVSEEPLS 780
DLPLTSETSSVSSMLLTSETTFVSSLPLPSETSPISNSSINERMAHQQRKSPSVSEEPLS
Sbjct: 721 DLPLTSETSSVSSMLLTSETTFVSSLPLPSETSPISNSSINERMAHQQRKSPSVSEEPLS 780
Query: 781 PQKDESSATAKPLGENLTSQQKNLSNTPEPIIMSSSSIAPEAFPSEDLHNKTLSQQTCKS 840
PQKDESSATAKPLGENLTSQQKNLSNTPEPIIMSSSSIAPEAFPSEDLHNKTLSQQTCKS
Sbjct: 781 PQKDESSATAKPLGENLTSQQKNLSNTPEPIIMSSSSIAPEAFPSEDLHNKTLSQQTCKS 840
Query: 841 HVDTEKPYPASIPELASTEMIKVKNHSVLQRTEKKVLPSPLELSVFSEGTDNKGNELPSA 900
HVDTEKPYPASIPELASTEMIKVKNHSVLQRTEKKVLPSPLELSVFSEGTDNKGNELPSA
Sbjct: 841 HVDTEKPYPASIPELASTEMIKVKNHSVLQRTEKKVLPSPLELSVFSEGTDNKGNELPSA 900
Query: 901 KLQDKQYISSVDKAPFSEGSRNKTHKQGSTQSRLETSHTSKSSEPSKSPDGIRNESRDSE 960
KLQDKQYISSVDKAPFSEGSRNKTHKQGSTQSRLETSHTSKSSEPSKSPDGIRNESRDSE
Sbjct: 901 KLQDKQYISSVDKAPFSEGSRNKTHKQGSTQSRLETSHTSKSSEPSKSPDGIRNESRDSE 960
Query: 961 ISKRKTAEQHSFGICKEKRARIEDDQSTRNISSSSPPEKEQPPREEPRVPPLKIQLSKIG 1020
ISKRKTAEQHSFGICKEKRARIEDDQSTRNISSSSPPEKEQPPREEPRVPPLKIQLSKIG
Sbjct: 961 ISKRKTAEQHSFGICKEKRARIEDDQSTRNISSSSPPEKEQPPREEPRVPPLKIQLSKIG 1020
Query: 1021 PPFIIKSQPVSKPESRASTSTSVSGGRNTGARTLADIKARAQQARAQREAAAAAAVAAAA 1080
PPFIIKSQPVSKPESRASTSTSVSGGRNTGARTLADIKARAQQARAQREAAAAAAVAAAA
Sbjct: 1021 PPFIIKSQPVSKPESRASTSTSVSGGRNTGARTLADIKARAQQARAQREAAAAAAVAAAA 1080
Query: 1081 SIVSGAMGSPGEGGKTRTLAHIKEQTKAKLFAKHQARAHLFQTSKETRLPPPLSSKEGPP 1140
SIVSGAMGSPGEGGKTRTLAHIKEQTKAKLFAKHQARAHLFQTSKETRLPPPLSSKEGPP
Sbjct: 1081 SIVSGAMGSPGEGGKTRTLAHIKEQTKAKLFAKHQARAHLFQTSKETRLPPPLSSKEGPP 1140
Query: 1141 NLEVSSTPETKMEGSTGVIIVNPNCRSPSNKSAHLRETTTVLQQSLNPSKLPETATDLSV 1200
NLEVSSTPETKMEGSTGVIIVNPNCRSPSNKSAHLRETTTVLQQSLNPSKLPETATDLSV
Sbjct: 1141 NLEVSSTPETKMEGSTGVIIVNPNCRSPSNKSAHLRETTTVLQQSLNPSKLPETATDLSV 1200
Query: 1201 HSSDENIPVSHLSEKIVSSTSSENSSVPMLFNKNSVPVSVCSTAISGAIKEHPFVSSVDK 1260
HSSDENIPVSHLSEKIVSSTSSENSSVPMLFNKNSVPVSVCSTAISGAIKEHPFVSSVDK
Sbjct: 1201 HSSDENIPVSHLSEKIVSSTSSENSSVPMLFNKNSVPVSVCSTAISGAIKEHPFVSSVDK 1260
Query: 1261 SSVLMSVDSANTTISACNISMLKTIQGTDTPCIAIIPKCIESTPISATTEGSSISSSMDD 1320
SSVLMSVDSANTTISACNISMLKTIQGTDTPCIAIIPKCIESTPISATTEGSSISSSMDD
Sbjct: 1261 SSVLMSVDSANTTISACNISMLKTIQGTDTPCIAIIPKCIESTPISATTEGSSISSSMDD 1320
Query: 1321 KQLLISSSSASNLVSTQYTSVPTPSIGNNLPNLSTSSVLIPPMGINNRFPSEKIAIPGSE 1380
KQLLISSSSASNLVSTQYTSVPTPSIGNNLPNLSTSSVLIPPMGINNRFPSEKIAIPGSE
Sbjct: 1321 KQLLISSSSASNLVSTQYTSVPTPSIGNNLPNLSTSSVLIPPMGINNRFPSEKIAIPGSE 1380
Query: 1381 EQATVSMGTTVRAALSCSDSVAVTDSLVAHPTVAMFTGNMLTINSYDSPPKLSAESLDKN 1440
EQATVSMGTTVRAALSCSDSVAVTDSLVAHPTVAMFTGNMLTINSYDSPPKLSAESLDKN
Sbjct: 1381 EQATVSMGTTVRAALSCSDSVAVTDSLVAHPTVAMFTGNMLTINSYDSPPKLSAESLDKN 1440
Query: 1441 SGPRNRADNSGKPQQPPGGFAPAAINRSIPCKVIVDHSTTLTSSLSLTVSVESSEASLDL 1500
SGPRNRADNSGKPQQPPGGFAPAAINRSIPCKVIVDHSTTLTSSLSLTVSVESSEASLDL
Sbjct: 1441 SGPRNRADNSGKPQQPPGGFAPAAINRSIPCKVIVDHSTTLTSSLSLTVSVESSEASLDL 1500
Query: 1501 QGRPVRTEASVQPVACPQVSVISRPEPVANEGIDHSSTFIAASAAKQDSKTLPATCTSLR 1560
QGRPVRTEASVQPVACPQVSVISRPEPVANEGIDHSSTFIAASAAKQDSKTLPATCTSLR
Sbjct: 1501 QGRPVRTEASVQPVACPQVSVISRPEPVANEGIDHSSTFIAASAAKQDSKTLPATCTSLR 1560
Query: 1561 ELPLVPDKLNEPTAPSHNFAEQARGPAPFKSEADTTCSNQYNPSNRICWNDDGMRSTGQP 1620
ELPLVPDKLNEPTAPSHNFAEQARGPAPFKSEADTTCSNQYNPSNRICWNDDGMRSTGQP
Sbjct: 1561 ELPLVPDKLNEPTAPSHNFAEQARGPAPFKSEADTTCSNQYNPSNRICWNDDGMRSTGQP 1620
Query: 1621 LVTHSGSSKQKEYLEQSCPKAIKTEHANYLNVSELHPRNLVTNVALPVKSELHEADKGFR 1680
LVTHSGSSKQKEYLEQSCPKAIKTEHANYLNVSELHPRNLVTNVALPVKSELHEADKGFR
Sbjct: 1621 LVTHSGSSKQKEYLEQSCPKAIKTEHANYLNVSELHPRNLVTNVALPVKSELHEADKGFR 1680
Query: 1681 MDTEDFPGPELPPPAAEGASSVQQTQNMKASTSSPMEEAISLATDALKRVPGAGSSGCRL 1740
MDTEDFPGPELPPPAAEGASSVQQTQNMKASTSSPMEEAISLATDALKRVPGAGSSGCRL
Sbjct: 1681 MDTEDFPGPELPPPAAEGASSVQQTQNMKASTSSPMEEAISLATDALKRVPGAGSSGCRL 1740
Query: 1741 SSVEANNPLVTQLLQGNLPLEKVLPQPRLGAKLEINRLPLPLQTTSVGKTAPERNVEIPP 1800
SSVEANNPLVTQLLQGNLPLEKVLPQPRLGAKLEINRLPLPLQTTSVGKTAPERNVEIPP
Sbjct: 1741 SSVEANNPLVTQLLQGNLPLEKVLPQPRLGAKLEINRLPLPLQTTSVGKTAPERNVEIPP 1800
Query: 1801 SSPNPDGKGYLAGTLAPLQMRKRENHPKKRVARTVGEHTQVKCEPGKLLVEPDVKGVPCV 1860
SSPNPDGKGYLAGTLAPLQMRKRENHPKKRVARTVGEHTQVKCEPGKLLVEPDVKGVPCV
Sbjct: 1801 SSPNPDGKGYLAGTLAPLQMRKRENHPKKRVARTVGEHTQVKCEPGKLLVEPDVKGVPCV 1860
Query: 1861 ISSGISQLGHSQPFKQEWLNKHSMQNRIVHSPEVKQQKRLLPSCSFQQNLFHVDKNGGFH 1920
ISSGISQLGHSQPFKQEWLNKHSMQNRIVHSPEVKQQKRLLPSCSFQQNLFHVDKNGGFH
Sbjct: 1861 ISSGISQLGHSQPFKQEWLNKHSMQNRIVHSPEVKQQKRLLPSCSFQQNLFHVDKNGGFH 1920
Query: 1921 TDAGTSHRQQFYQMPVAARGPIPTAALLQASSKTPVGCNAFAFNRHLEQKGLGEVSLSSA 1980
TDAGTSHRQQFYQMPVAARGPIPTAALLQASSKTPVGCNAFAFNRHLEQKGLGEVSLSSA
Sbjct: 1921 TDAGTSHRQQFYQMPVAARGPIPTAALLQASSKTPVGCNAFAFNRHLEQKGLGEVSLSSA 1980
Query: 1981 PHQLRLANMLSPNMPMKEGDEVGGTAHTMPNKALVHPPPPPPPPPPPPLALPPPPPPPPP 2040
PHQLRLANMLSPNMPMKEGDEVGGTAHTMPNKALVHPPPPPPPPPPPPLALPPPPPPPPP
Sbjct: 1981 PHQLRLANMLSPNMPMKEGDEVGGTAHTMPNKALVHPPPPPPPPPPPPLALPPPPPPPPP 2040
Query: 2041 LPPPLPNAEVPSDQKQPPVTMETTKRLSWPQSTGICSNIKSEPLSFEEGLSSSCELGMKQ 2100
LPPPLPNAEVPSDQKQPPVTMETTKRLSWPQSTGICSNIKSEPLSFEEGLSSSCELGMKQ
Sbjct: 2041 LPPPLPNAEVPSDQKQPPVTMETTKRLSWPQSTGICSNIKSEPLSFEEGLSSSCELGMKQ 2100
Query: 2101 VSYDQNEMKEQLKAFALKSADFSSYLLSEPQKPFTQLAAQKMQVQQQQQLCGNYPTIHFG 2160
VSYDQNEMKEQLKAFALKSADFSSYLLSEPQKPFTQLAAQKMQVQQQQQLCGNYPTIHFG
Sbjct: 2101 VSYDQNEMKEQLKAFALKSADFSSYLLSEPQKPFTQLAAQKMQVQQQQQLCGNYPTIHFG 2160
Query: 2161 STSFKRAASAIEKSIGILGSGSNPATGLSGQNAQMPVQNFADSSNADELELKCSCRLKAM 2220
STSFKRAASAIEKSIGILGSGSNPATGLSGQNAQMPVQNFADSSNADELELKCSCRLKAM
Sbjct: 2161 STSFKRAASAIEKSIGILGSGSNPATGLSGQNAQMPVQNFADSSNADELELKCSCRLKAM 2220
Query: 2221 IVCKGCGAFCHDDCIGPSKLCVACLVVR 2248
IVCKGCGAFCHDDCIGPSKLCVACLVVR
Sbjct: 2221 IVCKGCGAFCHDDCIGPSKLCVACLVVR 2248
>gi|153792780 additional sex combs like 2 [Homo sapiens]
Length = 1435
Score = 358 bits (918), Expect = 4e-98
Identities = 311/968 (32%), Positives = 463/968 (47%), Gaps = 115/968 (11%)
Query: 1 MKDK-RKKKDRTWAEAARLALEKHPNSPMTAKQILEVIQKEGLKET-SGTSPLACLNAML 58
M++K R+KK RTWAEAA+ LEK+PN+PM+ K+IL+VIQ+EGLKE SGTSPLACLNAML
Sbjct: 1 MREKGRRKKGRTWAEAAKTVLEKYPNTPMSHKEILQVIQREGLKEIRSGTSPLACLNAML 60
Query: 59 HTNTRIGDGTFFKIPGKSGLYALKKE------ESSCPADGTLDLVCESELDGTDMAEANA 112
HTN+R +G F+K+PG+ G+Y LKK+ E S ++ + D +S+ + ++
Sbjct: 61 HTNSRGEEGIFYKVPGRMGVYTLKKDVPDGVKELSEGSEESSDGQSDSQSSENSSSSSDG 120
Query: 113 HGEENGVCSKQVTDEASSTRDSSLTNTAVQS-KLVSSFQQHTKKALKQALRQQQKR---- 167
+ G S+ +SS+ S + + + K++S Q+H+KKALKQAL+QQQ++
Sbjct: 121 GSNKEGKKSRWKRKVSSSSPQSGCPSPTIPAGKVISPSQKHSKKALKQALKQQQQKKQQQ 180
Query: 168 --RNGVSMMVN-----KTVPR----VVLTPLKVSDEQSDSPSGSESKNGEADSSDKEMKH 216
R +S+ N KTV V P +QSD +GS + + SS ++++
Sbjct: 181 QCRPSISISSNQHLSLKTVKAASDSVPAKPATWEGKQSDGQTGSPQNSNSSFSSSVKVEN 240
Query: 217 GQKSPTGKQTSQHLKRLKKSGLGHLKWTKAEDIDIETPGSILVNTNLRALINKHTFASLP 276
GK++ Q +RL +K TK DID+ETP SILVNTNLRALINKHTF+ LP
Sbjct: 241 TLLG-LGKKSFQRSERLHTR---QMKRTKCADIDVETPDSILVNTNLRALINKHTFSVLP 296
Query: 277 QHFQQYLLLLLPEVDRQMGSDGILRLSTSALNNEFFAYAAQGWKQRLAEGEFTPEMQLRI 336
QQ LLLLLPEVDRQ+G DG+++L+ SALNNEFF AAQGWK+RL+EGEFTPEMQ+RI
Sbjct: 297 GDCQQRLLLLLPEVDRQVGPDGLMKLNGSALNNEFFTSAAQGWKERLSEGEFTPEMQVRI 356
Query: 337 RQEIEKEKKTEPWKEKFFERFYGEKLGMSREESVKLTTGPNNAGAQSSSSCGTSGLPVSA 396
RQEIEKEKK EPWKE+FFE +YG+ G+S E+S KLT P++ + + + +PVS
Sbjct: 357 RQEIEKEKKVEPWKEQFFESYYGQSSGLSLEDSKKLTASPSDPKVKKTPAEQPKSMPVSE 416
Query: 397 QTAL----------AEQQPKSMKSPASPE---------PGFCATLCPMVEIPPKDIMAEL 437
+ + +++ M SP E P F + P+ + + L
Sbjct: 417 ASLIRIVPVVSQSECKEEALQMSSPGRKEECESQGEVQPNFSTSSEPL-------LSSAL 469
Query: 438 ESEDI--LIPEESVIQEEIAEEVETSICECQDE-NHKTIP---EFSEEAESLTNSH---- 487
+ ++ ++P + E++ E+ + E + E NH T SE ESL S
Sbjct: 470 NTHELSSILPIKCPKDEDLLEQKPVTSAEQESEKNHLTTASNYNKSESQESLVTSPSKPK 529
Query: 488 ----EEPQIAPPEDNLESCVMMNDVLETLPHIEVKIEGKSESPQEEMTVVIDQLEVCDSL 543
E+P + P M + L TL ++ ES + + ++ ++ V
Sbjct: 530 SPGVEKPIVKPTAGAGPQETNMKEPLATL------VDQSPESLKRKSSLTQEEAPVSWEK 583
Query: 544 IPSTSSMTHVSDTEHKESETAVETS-TPKIKTGSSSLEGQFPNEGIAID-MELQSDPEEQ 601
P TE+++ + + S P + G + P I + + Q
Sbjct: 584 RPRV--------TENRQHQQPFQVSPQPFLNRGDRIQVRKVPPLKIPVSRISPMPFHPSQ 635
Query: 602 LSENACISETSFSSESPEGACTSLPSPGGETQSTSEESCTPASLETTFCSEVSSTENTDK 661
+S A S +S + GA T ++ + A+ + V T
Sbjct: 636 VSPRARF-PVSITSPNRTGARTLADIKAKAQLVKAQRAAAAAAAAAAAAASVGGTIPGPG 694
Query: 662 YNQRNSTDENFHASLMSEISPISTSPEISEASLMSNLPLTSEASPVSN---LPLTSETSP 718
E SP S +SE L L S LP ET P
Sbjct: 695 PGGGQGPGEGGEGQTARGGSP--GSDRVSETGKGPTLELAGTGSRGGTRELLPCGPETQP 752
Query: 719 MSD---LPLTSETSSVSSMLL-----TSETTFVS----SLPLPSETSPISNSSINERMAH 766
S+ P ++ SVS L T VS S+P P+ + N +N A
Sbjct: 753 QSETKTTPSQAQPHSVSGAQLQQTPPVPPTPAVSGACTSVPSPAHIEKLDNEKLNPTRAT 812
Query: 767 QQRKSPSVSEEPLSPQKDESSATAKPLGENLTSQQKNLSNTPEPIIMSSSSIAPEAFPSE 826
S S + P S +++++ + P G L +S + ++ +A PS+
Sbjct: 813 ATVASVSHPQGPSSCRQEKAPS---PTGPAL------ISGASPVHCAADGTVELKAGPSK 863
Query: 827 DLHNKTLSQQTCKSHVDTEKPYP-ASIPELASTEMIKVKNHSVLQRTEKKVLPS---PLE 882
++ N + S +T S P P S+ A+ E + V S PS P
Sbjct: 864 NIPNPSASSKTDASVPVAVTPSPLTSLLTTATLEKLPVPQVSATTAPAGSAPPSSTLPAA 923
Query: 883 LSVFSEGT 890
S+ + GT
Sbjct: 924 SSLKTPGT 931
Score = 93.2 bits (230), Expect = 3e-18
Identities = 43/89 (48%), Positives = 56/89 (62%)
Query: 2160 GSTSFKRAASAIEKSIGILGSGSNPATGLSGQNAQMPVQNFADSSNADELELKCSCRLKA 2219
GS + S+ + ++ A S +PVQ F++ ++ + KC CRLKA
Sbjct: 1347 GSQVSSNVGDVMSFSVTVTTIPASQAMNPSSHGQTIPVQAFSEENSIEGTPSKCYCRLKA 1406
Query: 2220 MIVCKGCGAFCHDDCIGPSKLCVACLVVR 2248
MI+CKGCGAFCHDDCIGPSKLCV+CLVVR
Sbjct: 1407 MIMCKGCGAFCHDDCIGPSKLCVSCLVVR 1435
Score = 86.3 bits (212), Expect = 3e-16
Identities = 79/267 (29%), Positives = 123/267 (46%), Gaps = 20/267 (7%)
Query: 835 QQTCKSHVDTEKPYPASIPELASTEMIKVKNHSVLQRTEKKVLPSPLELSVFSEGTDNKG 894
++ C+S + + + S L S+ + + S+L K + V S +++
Sbjct: 444 KEECESQGEVQPNFSTSSEPLLSSALNTHELSSILPIKCPKDEDLLEQKPVTSAEQESEK 503
Query: 895 NELPSA----KLQDKQYISSVDKAPFSEGSRNKTHKQGSTQSRLETSHTSKSSEPSKSPD 950
N L +A K + ++ + + P S G K + ET+ K P
Sbjct: 504 NHLTTASNYNKSESQESLVTSPSKPKSPGVEKPIVKPTAGAGPQETN--------MKEPL 555
Query: 951 GIRNESRDSEISKRKTAEQHSFGICKEKRARIEDDQSTRNISSSSP-PEKEQPPREEPR- 1008
+ + ++ + Q + EKR R+ +++ + SP P + R + R
Sbjct: 556 ATLVDQSPESLKRKSSLTQEEAPVSWEKRPRVTENRQHQQPFQVSPQPFLNRGDRIQVRK 615
Query: 1009 VPPLKIQLSKIGP-PFIIKSQPVSKPESRASTSTSVSGGRNTGARTLADIKARAQQARAQ 1067
VPPLKI +S+I P PF S+ RA S++ TGARTLADIKA+AQ +AQ
Sbjct: 616 VPPLKIPVSRISPMPF-----HPSQVSPRARFPVSITSPNRTGARTLADIKAKAQLVKAQ 670
Query: 1068 REAAAAAAVAAAASIVSGAMGSPGEGG 1094
R AAAAAA AAAA+ V G + PG GG
Sbjct: 671 RAAAAAAAAAAAAASVGGTIPGPGPGG 697
Score = 47.4 bits (111), Expect = 2e-04
Identities = 74/304 (24%), Positives = 106/304 (34%), Gaps = 76/304 (25%)
Query: 1482 TSSLSLTVSVESSEASLDLQGRPVRTEASVQPVACPQVSVISRPEPVANEGIDHSSTFIA 1541
T S T + S + G ++ V P + S P P E +D+
Sbjct: 750 TQPQSETKTTPSQAQPHSVSGAQLQQTPPVPPTPAVSGACTSVPSPAHIEKLDNEKLNPT 809
Query: 1542 ASAAKQDSKTLPATCTSLRELPLVPDKLNEPTAPSHNFAEQARGPAPFKSEADTTCSNQY 1601
+ A S + P +S R+ +K PT P+ G +P AD T +
Sbjct: 810 RATATVASVSHPQGPSSCRQ-----EKAPSPTGPA-----LISGASPVHCAADGTVELKA 859
Query: 1602 NPSNRICWNDDGMRSTGQPLVTHSGSSKQKEYLEQSCPKAIKTEHANYLNVSELHPRNLV 1661
PS I S SSK + S P A+ L +
Sbjct: 860 GPSKNI--------------PNPSASSKT----DASVPVAVTPSPLTSLLTT-------A 894
Query: 1662 TNVALPVKSELHEADKGFRMDTEDFPGPELPP----PAAEGASSVQQTQNMKASTSSPME 1717
T LPV ++ P PP PAA + + NM T P
Sbjct: 895 TLEKLPVP----------QVSATTAPAGSAPPSSTLPAASSLKTPGTSLNMNGPTLRPT- 943
Query: 1718 EAISLATDALKRVPGAGSSGCRLSSVEANNPLVTQLLQG-NLPLEKVLPQPRLGAKLEIN 1776
SS+ ANNPLVTQLLQG ++P+E++LP+P K+E+
Sbjct: 944 -----------------------SSIPANNPLVTQLLQGKDVPMEQILPKPL--TKVEMK 978
Query: 1777 RLPL 1780
+PL
Sbjct: 979 TVPL 982
Score = 43.5 bits (101), Expect = 0.002
Identities = 72/309 (23%), Positives = 117/309 (37%), Gaps = 48/309 (15%)
Query: 620 GACTSLPSPGGETQSTSEESCTPASLETTFCSEVSSTENTDKYNQRNSTDENFHASLMSE 679
GACTS+PSP + E P T S VS + Q + A L+S
Sbjct: 787 GACTSVPSP-AHIEKLDNEKLNPTRATATVAS-VSHPQGPSSCRQEKAPSPTGPA-LISG 843
Query: 680 ISPISTSPEIS---EASLMSNLPLTSEASPV-SNLPLTSETSPMSDLPLTSETSSVSSML 735
SP+ + + + +A N+P S +S +++P+ SP++ L LT+ T +
Sbjct: 844 ASPVHCAADGTVELKAGPSKNIPNPSASSKTDASVPVAVTPSPLTSL-LTTATLEKLPVP 902
Query: 736 LTSETTFVSSLPLPSETSPISNSSINERMAHQQRKSPSVSEEPLSPQKDESSATAKPLGE 795
S TT + PS T P ++S K+P S P +S+ P
Sbjct: 903 QVSATTAPAGSAPPSSTLPAASS----------LKTPGTSLNMNGPTLRPTSSI--PANN 950
Query: 796 NLTSQQKNLSNT------PEPIIMSSSSIAPEAFPSE----DLHNKTLSQQTCKSHVDTE 845
L +Q + P+P+ P E L ++ + + V+
Sbjct: 951 PLVTQLLQGKDVPMEQILPKPLTKVEMKTVPLTAKEERGMGALIATNTTENSTREEVNER 1010
Query: 846 KPYPASIPELASTEMIKVKNHSVLQRTEKKVLPSPLELSVFSEGTDNKGNELPSAKLQDK 905
+ +PA+ +L T LQ + +P PL+L FS EL + +
Sbjct: 1011 QSHPATQQQLGKT----------LQSKQLPQVPRPLQL--FS------AKELRDSSIDTH 1052
Query: 906 QYISSVDKA 914
QY + KA
Sbjct: 1053 QYHEGLSKA 1061
>gi|29570782 additional sex combs like 1 [Homo sapiens]
Length = 1541
Score = 335 bits (859), Expect = 3e-91
Identities = 300/988 (30%), Positives = 440/988 (44%), Gaps = 148/988 (14%)
Query: 1 MKDK-RKKKDRTWAEAARLALEKHPNSPMTAKQILEVIQKEGLKET-SGTSPLACLNAML 58
MKDK +KKK+RTWAEAARL LE + ++PMT KQIL+VI+ EGLKE SGTSPLACLNAML
Sbjct: 1 MKDKQKKKKERTWAEAARLVLENYSDAPMTPKQILQVIEAEGLKEMRSGTSPLACLNAML 60
Query: 59 HTNTRIGDGTFFKIPGKSGLYALKKE-----------ESSCPADGTLDLVCESELDGTDM 107
H+N+R G+G F+K+PG+ L+ LKK+ E P D ++++
Sbjct: 61 HSNSRGGEGLFYKLPGRISLFTLKKDALQWSRHPATVEGEEPED-------TADVESCGS 113
Query: 108 AEANAHGEENGVCSKQVTDEASSTRDSSLTNTAVQSKLVSSFQQHTKKALKQALRQQQKR 167
EA+ EN V + + AS + +S QS+ +S+ + + +A QA +QK+
Sbjct: 114 NEASTVSGENDVSLDETSSNASCSTES-------QSRPLSN-PRDSYRASSQA--NKQKK 163
Query: 168 RNGVSMMVNKTVPRVVLTPLKVSDEQSDSPSGSESKNGEADSSDKEMK------------ 215
+ GV + PRVVLTPLKV+ +S SG + + +S
Sbjct: 164 KTGVML------PRVVLTPLKVNGAHVESASGFSGCHADGESGSPSSSSSGSLALGSAAI 217
Query: 216 HGQKSPTGKQTSQHLKRLKKSGLGHLKWTKAEDIDIETPGSILVNTNLRALINKHTFASL 275
GQ T + + L+ +K G +K + E+ID ETPGSILVNTNLRALIN TF +L
Sbjct: 218 RGQAEVT-QDPAPLLRGFRKPATGQMKRNRGEEIDFETPGSILVNTNLRALINSRTFHAL 276
Query: 276 PQHFQQYLLLLLPEVDRQMGSDGILRLSTSALNNEFFAYAAQGWKQRLAEGEFTPEMQLR 335
P HFQQ LL LLPEVDRQ+G+DG+LRLS+SALNNEFF +AAQ W++RLA+GEFT EMQ+R
Sbjct: 277 PSHFQQQLLFLLPEVDRQVGTDGLLRLSSSALNNEFFTHAAQSWRERLADGEFTHEMQVR 336
Query: 336 IRQEIEKEKKTEPWKEKFFERFYGEKLGMSREESVKLTTGPNNAGAQSSSSCGTSGLPVS 395
IRQE+EKEKK E WKEKFFE +YG+KLG+++EES++ G A +S + +
Sbjct: 337 IRQEMEKEKKVEQWKEKFFEDYYGQKLGLTKEESLQQNVGQEEAEIKSGLCVPGESVRIQ 396
Query: 396 AQTALAEQQPKSMKSPASPEPGFCATLCPMVEIPPKDIMAELESEDILIPEESVIQEEIA 455
A Q+ K + P+ A +++ + ESE + ++ A
Sbjct: 397 RGPA-TRQRDGHFKKRSRPDLRTRAR---------RNLYKKQESEQAGVAKD-------A 439
Query: 456 EEVETSICECQDENHKTIPEFSEEAESLTNSHEEPQIAPPE--------------DNLES 501
+ V + + +D KT P S P + PE DNL
Sbjct: 440 KSVASDVPLYKDGEAKTDPAGLSSPHLPGTSSAAPDLEGPEFPVESVASRIQAEPDNLAR 499
Query: 502 CVMMNDVLETLPHIEVKIEGKSESPQEEMTVVIDQLEVCDSLIPSTSSMTHVSDTEH--K 559
D + +LP V E K + + + S + ++ H K
Sbjct: 500 ASASPDRIPSLPQETVDQEPKDQKRKSFEQAASASFPEKKPRLEDRQSFRNTIESVHTEK 559
Query: 560 ESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMELQSDPEEQLSENACISETSFSSESPE 619
T E P I+ S ++ + +G P Q+ I T S
Sbjct: 560 PQPTKEEPKVPPIRIQLSRIKPPWVVKG---------QPTYQICPR-IIPTTESSCRGWT 609
Query: 620 GACT-------SLPSPGGETQSTSEESCTPASLETTFCSEVSSTENTDKYNQRNSTDENF 672
GA T +L G E+ T A + + +S+ +
Sbjct: 610 GARTLADIKARALQVRGARGHHCHREAATTAIGGGGGPGGGGGGATDEGGGRGSSSGDGG 669
Query: 673 HASLMSE-----ISPISTSPEISEASLMSNLPLTSEASPVSNLPLTSETSPMSDLP-LTS 726
A E +P + ++ L+ PL E + + DLP L
Sbjct: 670 EACGHPEPRGGPSTPGKCTSDLQRTQLLPPYPLNGEHTQAGT---AMSRARREDLPSLRK 726
Query: 727 ETSSV---SSMLLTSETTFVSSLPL------PSETSPI--SNSSINERMAHQQRKSPSVS 775
E S + +++ LT S LP+ P + P+ S +S+ ER+ Q + P V
Sbjct: 727 EESCLLQRATVGLTDGLGDASQLPVAPTGDQPCQALPLLSSQTSVAERLVEQPQLHPDVR 786
Query: 776 EEPLS-----PQKDESSATAKPLG-------------ENLTSQQKNLSNTPEPIIMSSSS 817
E S DE P E T Q + T + + + S
Sbjct: 787 TECESGTTSWESDDEEQGPTVPADNGPIPSLVGDDTLEKGTGQALDSHPTMKDPVNVTPS 846
Query: 818 IAPEAFPSEDLHNKTLSQQTCKSHVDTEKPYPASIPEL--ASTEMIKVKNHSVLQRTEKK 875
PE+ P++ L N+ D E S P + + T +K +++ +
Sbjct: 847 STPESSPTDCLQNRAF---------DDELGLGGSCPPMRESDTRQENLKTKALVSNSSLH 897
Query: 876 VLPSPLELSVFSEGTDNKGNELPSAKLQ 903
+P P V + +PS + Q
Sbjct: 898 WIPIPSNDEVVKQPKPESREHIPSVEPQ 925
Score = 110 bits (275), Expect = 2e-23
Identities = 78/231 (33%), Positives = 111/231 (48%), Gaps = 21/231 (9%)
Query: 2033 PPPPPPPPLPPPLPNAEVPSDQKQPPVTMET----TKRLSW-PQSTGICSNIKSEPLSFE 2087
P P P PLP +P PS + P + T R W P+ ++K+E
Sbjct: 1317 PRPADPMPLPAEIPPV-FPSGKLGPSTNSMSGGVQTPREDWAPKPHAFVGSVKNEKTFVG 1375
Query: 2088 EGLSSSCELGMKQVSYDQNEMKEQLKAFAL-------KSADFSSYLLSEPQKPFTQLAAQ 2140
L ++ E K + E+ L+ K LSEP +P ++
Sbjct: 1376 GPLKANAE-NRKATGHSPLELVGHLEGMPFVMDLPFWKLPREPGKGLSEPLEP----SSL 1430
Query: 2141 KMQVQQQQQLCGNYPTIHFGSTSFKRAASAIEKSIGILGSG---SNPATGLSGQNAQMPV 2197
Q+ +Q G + STSF ++S+ G+ GS S+ A + +A + +
Sbjct: 1431 PSQLSIKQAFYGKLSKLQLSSTSFNYSSSSPTFPKGLAGSVVQLSHKANFGASHSASLSL 1490
Query: 2198 QNFADSSNADELELKCSCRLKAMIVCKGCGAFCHDDCIGPSKLCVACLVVR 2248
Q F DSS + + L+C+C LKAMI+C+GCGAFCHDDCIGPSKLCV CLVVR
Sbjct: 1491 QMFTDSSTVESISLQCACSLKAMIMCQGCGAFCHDDCIGPSKLCVLCLVVR 1541
Score = 106 bits (265), Expect = 2e-22
Identities = 68/166 (40%), Positives = 88/166 (53%), Gaps = 8/166 (4%)
Query: 934 LETSHTSKSSEPSKSPDGIRNESRDSEISKRKTAEQHSFGICKEKRARIEDDQSTRNISS 993
L + S PS + + E +D KRK+ EQ + EK+ R+ED QS RN
Sbjct: 497 LARASASPDRIPSLPQETVDQEPKDQ---KRKSFEQAASASFPEKKPRLEDRQSFRNTIE 553
Query: 994 SSPPEKEQPPREEPRVPPLKIQLSKIGPPFIIKSQPVSKPESRASTSTSVSGGRNTGART 1053
S EK QP +EEP+VPP++IQLS+I PP+++K QP + R +T S TGART
Sbjct: 554 SVHTEKPQPTKEEPKVPPIRIQLSRIKPPWVVKGQPTYQICPRIIPTTESSCRGWTGART 613
Query: 1054 LADIKARAQQARAQR-----EAAAAAAVAAAASIVSGAMGSPGEGG 1094
LADIKARA Q R R AA A+ G G+ EGG
Sbjct: 614 LADIKARALQVRGARGHHCHREAATTAIGGGGGPGGGGGGATDEGG 659
Score = 49.7 bits (117), Expect = 3e-05
Identities = 106/494 (21%), Positives = 168/494 (34%), Gaps = 85/494 (17%)
Query: 1342 PTPSIGNNLPNLSTSSV----LIPPMGINNRFPSEKIAIPGSEEQATVSMGTTV-----R 1392
P P G + P TS + L+PP +N A+ + + S+ R
Sbjct: 675 PEPRGGPSTPGKCTSDLQRTQLLPPYPLNGEHTQAGTAMSRARREDLPSLRKEESCLLQR 734
Query: 1393 AALSCSDSVAVTDSLVAHPT-------VAMFTGNMLTINSYDSPPKL------------- 1432
A + +D + L PT + + + P+L
Sbjct: 735 ATVGLTDGLGDASQLPVAPTGDQPCQALPLLSSQTSVAERLVEQPQLHPDVRTECESGTT 794
Query: 1433 SAESLDKNSGPRNRADNSGKPQQPPGGFAPAAINRSIPCKVIVDHSTTLTSSLSLTVSVE 1492
S ES D+ GP ADN P +++ D T+ +++T S
Sbjct: 795 SWESDDEEQGPTVPADNGPIPSLVGDDTLEKGTGQAL------DSHPTMKDPVNVTPSST 848
Query: 1493 SSEASLD-LQGRPVRTEASVQPVACPQVSVISRPEPVANEGIDHSSTFIAASAAKQDSKT 1551
+ D LQ R E + P +R E + + + +S+ D
Sbjct: 849 PESSPTDCLQNRAFDDELGLGGSCPPMRESDTRQENLKTKALVSNSSLHWIPIPSNDEVV 908
Query: 1552 LPATCTSLRELPLVPDKLNEPTAPSHNFAEQARGPAPFKSEADTTCSNQYNPSNRIC--W 1609
S +P V ++ E + P P D T +P + + W
Sbjct: 909 KQPKPESREHIPSVEPQVGEEW--------EKAAPTPPALPGDLTAEEGLDPLDSLTSLW 960
Query: 1610 NDDGMRSTGQPLVTHSGSSKQKEYLEQSCPKAIKTEHANYLNVSELHPRNLVTNVALPVK 1669
+ + GS Y +Q + +K + L P T+ A +
Sbjct: 961 T----------VPSRGGSDSNGSYCQQVDIEKLKINGDS----EALSPHGESTDTASDFE 1006
Query: 1670 SEL----HEAD-------KGFRMDTEDFPGPELPPPAAEGASS---VQQTQNMKASTS-- 1713
L EAD KG +D ++ P P ++ V +T M A S
Sbjct: 1007 GHLTEDSSEADTREAAVTKGSSVDKDEKPNWNQSAPLSKVNGDMRLVTRTDGMVAPQSWV 1066
Query: 1714 -------SPMEEAISLATDALKRVPGAGSSGCRLSSVEANNPLVTQLLQGNLPLEKVLPQ 1766
+ +++ LA+ + P A SSVEA NPLV QLLQG+LPLEKVLP
Sbjct: 1067 SRVCAVRQKIPDSLLLASTEYQ--PRAVCLSMPGSSVEATNPLVMQLLQGSLPLEKVLPP 1124
Query: 1767 PRLGAKLEINRLPL 1780
+ E ++PL
Sbjct: 1125 AHDDSMSESPQVPL 1138
>gi|91982772 mucin 17 [Homo sapiens]
Length = 4493
Score = 131 bits (329), Expect = 9e-30
Identities = 299/1447 (20%), Positives = 521/1447 (36%), Gaps = 175/1447 (12%)
Query: 367 EESVKLTTGPNNAGAQSSSSCGTSGL-PVSAQTALAEQ-QPKSMKSPASPEPGFCATLC- 423
E S LT+ P + ++S T + PV T + +P S+ + A +TL
Sbjct: 331 EGSTPLTSTPASTMPVATSEMSTLSITPVDTSTLVTTSTEPSSLPTTAEATSMLTSTLSE 390
Query: 424 ---PMVEIPPKDIMAELE--SEDILIPEESVIQEEIAEEVETSICECQDENHKTIPEFSE 478
P+ +P I+ S IP +S A E +S +D + T S
Sbjct: 391 GSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIAT----ST 446
Query: 479 EAESLTNSHEEPQIAPPEDNLESCVMMNDVLETLPHIEVKIEGKSESPQEEMTVVIDQLE 538
+E T P P + E+ + +++ + E S P E+ +
Sbjct: 447 PSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTP 506
Query: 539 VCDSL---IPSTSSMTHVSDTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMELQ 595
S S S+M S S T V+TSTP + T S + EG +I
Sbjct: 507 SEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTP-VTTSSEASSSSTTPEGTSIPTSTP 565
Query: 596 SDPEEQLSENACISETSFSSESPEGACTSLPSPGGETQSTSEESCTPASLETTFCSEVSS 655
S+ L+ + SSE+ + T P+ +TS E AS +T S
Sbjct: 566 SEGSTPLTNMPVSTRLVVSSEASTTSTT--PADSNTFVTTSSE----ASSSSTTAEGTSM 619
Query: 656 TENTDKYNQRNSTDENFHAS----LMSEISPISTSPEISEASLMSNLPLTSEASPVSNLP 711
+T Y++R +T + S SE S +ST+P S + ++ TS ++
Sbjct: 620 PTST--YSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTS 677
Query: 712 LTSETSPMSDLPLTSETSSVSSMLLTSETTFVSSLPLPSETSPISNSSINERMAHQQRKS 771
+ + T PLTS + ++++ +SE + +S+ P+ + T P++ S+ + +
Sbjct: 678 MPTSTYTEGSTPLTSMPVN-TTLVASSEASTLSTTPVDTST-PVTTST---EASSSPTTA 732
Query: 772 PSVSEEPLSPQKDESSATAKPLGENL--TSQQKNLSNTP-----EPIIMSSSSIAPEAFP 824
S +P + + T+ P+ + L +S+ LS TP + +S +P
Sbjct: 733 DGASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTE 792
Query: 825 SEDLHNKTLSQQTCKSHVDTEKPYPASIPELASTEMIKVKNHS-VLQRTEKKVLPSPLE- 882
+ T S+ + P + PE ++ V ++S V TE P+P E
Sbjct: 793 GTSMPISTPSEGSPLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEG 852
Query: 883 ----LSVFSEGTDNKGNELPSAKLQDKQYISSVDKAPFSEGSRNKTHKQGSTQSRLETSH 938
S +SEG + S L IS++ P T ST++R +
Sbjct: 853 TSMPTSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVD----TSTPVTNSTEARSSPTT 908
Query: 939 TSKSSEPSKSPDGIRNESRDSEISKRKTAEQHSFGICKEKRARIEDDQSTRNISSSSPPE 998
+ +S P+ +P + + + + E R T ++S
Sbjct: 909 SEGTSMPTSTPG-------EGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEA 961
Query: 999 KEQPPREEPRVPPLKIQLSKIGPPFIIKSQPVSK---PESRASTSTSVSGGRNTGARTLA 1055
P E P P + S PVS S AST ++ NT T
Sbjct: 962 TSSPTTAEGTSIPTSTPSEGTTP---LTSTPVSHTLVANSEASTLSTTPVDSNTPLTTST 1018
Query: 1056 DIKARAQQARAQREAAAAAAVAAAASIVSGAMGSPGEGGKTRTLAHIKEQTKAKLFAKHQ 1115
+ + A + + + + +T TL+ T + Q
Sbjct: 1019 EASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQ 1078
Query: 1116 ARAHLFQTSKETRLPPPLSSKEGPPNLEVSSTPETKMEGSTGVIIVNP-NCRSPSNKSAH 1174
A + T+ T +P S+ P V + + + P + P S
Sbjct: 1079 ASSS-STTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTE 1137
Query: 1175 LRETTTVLQQSLNPSKLPE----------TATDLSVHSSDENIPVSHLSEKIVSSTSSEN 1224
+ T + + P+ P +T L V S + + + K +TS+E
Sbjct: 1138 ASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEA 1197
Query: 1225 SSVPMLFNKNSVPVSV---CSTAISGAIKEHPFVSSVDKSSVLMS-VD-SANTTISACNI 1279
SS P S+P S ST ++ H V+S + S++ S VD S T SA
Sbjct: 1198 SSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETS 1257
Query: 1280 SMLKTIQGTDTPCIAIIPKCIESTPISATTEGSSISSSMDDKQLLISSSSASNLVST--- 1336
S T +GT S P S T+EGS++ +S+ L++S AS L++T
Sbjct: 1258 SSPTTAEGT-------------SLPTSTTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVD 1304
Query: 1337 ---------QYTSVPTPSIGNNLPNLSTSSVLIPPMGINNRFPSEKIAIPGSEEQATVSM 1387
+ +S PTP+ G ++P + S R P I + S
Sbjct: 1305 TKGPVVTSNEVSSSPTPAEGTSMPTSTYS---------EGRTPLTSIPV---NTTLVASS 1352
Query: 1388 GTTVRAALSCSDSVAVTDSLVAHPTVAMFTGNMLTINSYDSPPKLSAESLDKNSGPRNRA 1447
++ + +S VT S A + G + NS S S+ ++ P +
Sbjct: 1353 AISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMP-NSNPSEGTTPLTSIPVSTTPVVSS 1411
Query: 1448 DNSGKPQQPPGGFAPAAINRSIPCKVIVDHSTTLTSSLSLTVSVES-SEASLDLQGRPVR 1506
+ S P ++ S P + +++ T++ +++ + SE L+ PV
Sbjct: 1412 EASTLSATP--------VDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPV- 1462
Query: 1507 TEASVQPVACPQVSVISRPEPVANEGIDHSSTFIAASAAKQDSKTLPATCTSLRELPLVP 1566
S PVA + S +S PV + +ST +++S + ++ + S L
Sbjct: 1463 ---SNTPVANSEASTLS-TTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALTS 1518
Query: 1567 DKLNEPTAPSHNFAEQARGPAPFKSEADTTCSNQYNPSNRICWNDDGMRSTGQPLVTHSG 1626
++ T S + PA + T +P+ DG T T+S
Sbjct: 1519 IPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTTA-----DG---TSMQTSTYSE 1570
Query: 1627 SSKQKEYLEQSCPKAIKTEHANYLNVSELHPRNLVTNVALPVKSELHEADKGFRMDTEDF 1686
S L S + +E AN L+ + + + VT
Sbjct: 1571 GSTPLTSLPVSTMLVVSSE-ANTLSTTPIDSKTQVT------------------------ 1605
Query: 1687 PGPELPPPAAEGASSVQQTQNMKASTSSPMEEAISLATDALKRVPGAGSSGCRLSS--VE 1744
A+ ASS + + S+P E + L + + P A LS+ V+
Sbjct: 1606 --------ASTEASSSTTAEGSSMTISTPSEGSPLLTSIPVSTTPVASPEASTLSTTPVD 1657
Query: 1745 ANNPLVT 1751
+N+P++T
Sbjct: 1658 SNSPVIT 1664
Score = 115 bits (288), Expect = 5e-25
Identities = 276/1296 (21%), Positives = 485/1296 (37%), Gaps = 184/1296 (14%)
Query: 523 SESPQEEMTVVIDQLEVCDSLIPSTSSMTHVSDTEHKESETAVETSTPKIKTGSSSLEGQ 582
S +P + T V E S SSMT + +E T++ ST + + +S
Sbjct: 1594 STTPIDSKTQVTASTEASSSTTAEGSSMTISTPSEGSPLLTSIPVSTTPVASPEASTLST 1653
Query: 583 FPNEGIAIDMELQSDPEEQLSENACISETSFSSESPEGACTSLPSPGGETQSTSEESCTP 642
P + S + I+ T SS TS+P+ ST E TP
Sbjct: 1654 TPVD----------------SNSPVITSTEVSSSPTPAEGTSMPT------STYTEGRTP 1691
Query: 643 ASLETTFCSEVSSTENTDKYNQRNSTDENFHASLMSEISPISTSPEISEASLMSNLPLTS 702
+ T + V+S S + + +P++TS E + P TS
Sbjct: 1692 LTSITVRTTPVAS-----------SAISTLSTTPVDNSTPVTTSTEARSS------PTTS 1734
Query: 703 EASPVSNLPLTSETSPMSDLPLTSETSSVSSMLLTSETTFVSSLPLPSETSPISNSSINE 762
E + + N + T+P++ +P++ ++ +L+SE + +S+ P+ + T P++ S+
Sbjct: 1735 EGTSMPNSTPSEGTTPLTSIPVS------TTPVLSSEASTLSATPIDTST-PVTTST--- 1784
Query: 763 RMAHQQRKSPSVSEEPLSPQKDESSA----TAKPLGENL--TSQQKNLSNTP---EPIIM 813
+ SP+ +E P S T+ P+ L S+ LS TP ++
Sbjct: 1785 ----EATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVV 1840
Query: 814 SSSSIAPEAFPSEDLHNKTLSQQTCKSHVDTEKPYPASIPELASTEMIKVKNHSVLQRTE 873
+S++++ P+E +++ T P S +AS+E + + T
Sbjct: 1841 TSTAVSSSPTPAE---GTSIATSTPSEGSTALTSIPVSTTTVASSETNTLSTTPAVTST- 1896
Query: 874 KKVLPSPLELSVFSEGTDNKGNELP-SAKLQDKQYISSVDKAPFSEGSRN-KTHKQGSTQ 931
P V S T G+ +P S + + ++S+ + + S T
Sbjct: 1897 ----PVTTYAQVSSSPTTADGSSMPTSTPREGRPPLTSIPVSTTTVASSEINTLSTTLAD 1952
Query: 932 SRLE-TSHTSKSSEPSKSPDGIRNESRDSEISKRKTAEQHSFGICKEKRARIEDDQSTRN 990
+R T+++ SS P+ + SE S T+ S + A ST
Sbjct: 1953 TRTPVTTYSQASSSPTTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSEA---STLSTTP 2009
Query: 991 ISSSSPPEKEQPPREEPRVPPLKIQLSKIGPPFIIKSQPVSKPESRA----STSTSVSGG 1046
+ +S+P P + G I S P + A ST+ VS
Sbjct: 2010 VDTSTPATTSTEGSSSP---------TTAGGTSIQTSTPSERTTPLAGMPVSTTLVVSSE 2060
Query: 1047 RNTGARTLADIKARAQQARAQREAAAAAAVAAAASIVSGAMGSPGEGGKTRTLAHIKEQT 1106
NT + T D K Q EA+++A ++ +S +P EG T +
Sbjct: 2061 GNTLSTTPVDSKT---QVTNSTEASSSATAEGSSMTIS----APSEGSPLLTSIPLSTTP 2113
Query: 1107 KAKLFAKHQARAHLFQTSKETRLPPPLSSKE---GPPNLEVSS----------TPETKME 1153
A A T+ P ++S E P E +S TP T M
Sbjct: 2114 VA------SPEASTLSTTPVDSNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSMP 2167
Query: 1154 GSTGVIIVNPNCRSPSNKSAHLRETTTVLQQSLNPSKLPETATDLSVHSSD--------E 1205
ST V+ + + S S +T+T + S P T+ S+ +S
Sbjct: 2168 VSTTVVASS----AISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFT 2223
Query: 1206 NIPVSHLSEKIVSSTSSENSSVPMLFNKNSVPVSVCSTAISGAIKEH----PFVSSVDKS 1261
++PVS + +V+S +S S+ P+ S PV+ + A S P + + +
Sbjct: 2224 SMPVSTM--PVVTSEASTLSATPV---DTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGT 2278
Query: 1262 SVLMSVDSANTTISACNISMLKTIQGTDTPCIAIIPKCIESTPISATTEGSSISSSMDDK 1321
+ L S+ ++T ++ +S L T TP + +TP + +TE SS + +
Sbjct: 2279 TPLTSIPVSHTLVANSEVSTLST-----TPVDS-------NTPFTTSTEASSPPPTAEGT 2326
Query: 1322 QLLISSSSASNLVSTQYTSVPTPSIGNNLPNLST--SSVLIPPMGINNRFPSEKIAIPGS 1379
+ S+SS N T+ T LST + P + S A S
Sbjct: 2327 SMPTSTSSEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTS 2386
Query: 1380 EEQATVSMGTTVRAALSCSDSVAVTDSLVAHPTVAMFTGNMLTINSYDSPPKLSAESLDK 1439
+T S G+T ++ S V+ H T + T +T ++ S +AE
Sbjct: 2387 MPTSTYSEGSTPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSI 2446
Query: 1440 NSGPRNRADN-------SGKP--QQPPGGFAPAAINRSIPCKVIVDHSTTLTSSLSLTVS 1490
+ P + S P G + ++ S P + S++ T++ + V
Sbjct: 2447 PTSPPSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVP 2506
Query: 1491 VE-SSEASLDLQGRPVRTEASVQPVACPQVSVISRPEPVANEGIDHSSTFIAASAAKQDS 1549
+ +SE S L PV S PVA P+ S +S PV + +ST I++SA +
Sbjct: 2507 ISTASEGSTLLTSIPV----STTPVASPEASTLS-TTPVDSNSPVVTSTEISSSATSAEG 2561
Query: 1550 KTLPATCTSLRELPLVPDKLNEPTAPSHNFAEQARGPAPFKSEADTTCSNQYNPSNRICW 1609
++P + S PL ++ S + + P T+ +P+
Sbjct: 2562 TSMPTSTYSEGSTPLRSMPVSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTT---- 2617
Query: 1610 NDDGMRSTGQPLVTHSG-SSKQKEYLEQSCPKAIKTEHANYLNVSELHPRNLVTNVALPV 1668
+ T P+ T S S+ L + P + + A+ L+ + + R LVT
Sbjct: 2618 ----AKDTSMPISTPSEVSTSLTSILVSTMP--VASSEASTLSTTPVDTRTLVTTST--G 2669
Query: 1669 KSELHEADKGFRMDTEDFPGPELPPPAAEGASSVQQTQNMKAST--SSPMEEA--ISLAT 1724
S +G M T PG E P S N +AST ++P++ + ++ +
Sbjct: 2670 TSSSPTTAEGSSMPTST-PG-ERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSA 2727
Query: 1725 DALKRVPGAGSSGCRLSSVEANNPLVTQLLQGNLPL 1760
+A A + R+S+ + +T +L LP+
Sbjct: 2728 EASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPV 2763
Score = 114 bits (286), Expect = 8e-25
Identities = 287/1354 (21%), Positives = 492/1354 (36%), Gaps = 200/1354 (14%)
Query: 553 VSDTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMELQSDPEEQL---------- 602
VS S T V+TSTP + T + + EG +I S+ L
Sbjct: 937 VSSEARTLSATPVDTSTP-VTTSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLV 995
Query: 603 --SENACISETSFSSESPEGACTSLPSPGGETQSTSEESCTP-----------------A 643
SE + +S T S +P T SP + TS + TP A
Sbjct: 996 ANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVA 1055
Query: 644 SLETTFCSEVSSTENTD--KYNQRNSTDENFHASLMSEISPISTSPEISEASLMSNLPLT 701
S ET+ S + +T Y+Q +S+ + M + S ++ + + L ++
Sbjct: 1056 SSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVS 1115
Query: 702 SEASPVS------NLPLTSETSPMSDLPLTSETSSVSSMLLTSETTFVSSLP------LP 749
SEAS +S ++P+T+ T S P T+E +S+ + + TT ++S+P +
Sbjct: 1116 SEASTLSTTPVDTSIPVTTSTEASSS-PTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVS 1174
Query: 750 SETSPISNSSINERMAHQQRKSPSVSEEPLSPQKDESSATAKPLGENLTS-QQKNLSNTP 808
SE + +S + ++ + Q S S P P + +S GE T + +TP
Sbjct: 1175 SEANTLSTTPVDSKT--QVATSTEASSPP--PTAEVTSMPTSTPGERSTPLTSMPVRHTP 1230
Query: 809 EPIIMSSSSIAPEAFPSEDLHNKTLSQQTCKSHVDTE-KPYPASIPELASTEM--IKVKN 865
+ SS + P + T S +T S E P S ST + I V
Sbjct: 1231 ---VASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVST 1287
Query: 866 HSVLQRTEKKVLPSPLEL--------SVFSEGTDNKGNELPSAKLQDKQYISSVDKAPFS 917
V +L +P++ V S T +G +P++ S + P +
Sbjct: 1288 TLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTY-------SEGRTPLT 1340
Query: 918 EGSRNKTHKQGSTQSRLET------SHTSKSSEPSKSPDGIRNESRDSEISKRKTAEQHS 971
N T S S L T + + S+E SP S + T S
Sbjct: 1341 SIPVNTTLVASSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTS 1400
Query: 972 FGICKEKRARIEDDQSTRNISSSSPPEKEQPPREEPRVPPLKIQLSKIGPPFIIKSQPVS 1031
+ + + ST S++P + P I P S+ +
Sbjct: 1401 IPV--STTPVVSSEAST---LSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKT 1455
Query: 1032 KPESRASTSTSVSGGRNTGARTLADIKARAQQARAQREAAAAAAVAAAASIVSGAMGSPG 1091
+S ++T V+ N+ A TL+ + A +++ A + + A+ +P
Sbjct: 1456 PLKSIPVSNTPVA---NSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSI--AISTPS 1510
Query: 1092 EGGKTRTLAHIKEQTKAKLFAKHQARAHLFQTSKETRLPPPLSSKEGPPNLEVSSTPETK 1151
EG T + T A + E++S T
Sbjct: 1511 EGSTALTSIPVSTTTVA--------------------------------SSEINSLSTTP 1538
Query: 1152 MEGSTGVIIVNPNCRSPSNKSAHLRETTTVLQQSLNPSKLPETATDLSVHSSDENIPVSH 1211
ST V + SP+ +T+T + S + LP +T L V S + +
Sbjct: 1539 AVTSTPVTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLP-VSTMLVVSSEANTLSTTP 1597
Query: 1212 LSEKIVSSTSSENSSVPMLFNKNSVPVSVCSTAISGAIKEHPFVSSVDKSSVLMSVDSAN 1271
+ K + S+E SS S S IS + P ++S+ S+ ++ A+
Sbjct: 1598 IDSKTQVTASTEASS--------STTAEGSSMTISTPSEGSPLLTSIPVSTTPVASPEAS 1649
Query: 1272 TTISACNISMLKTIQGTDTPCIAIIPKCIEST--PISATTEGSSISSSMDDKQLLISSSS 1329
T + S I T+ ++ P E T P S TEG + +S+ + ++SS+
Sbjct: 1650 TLSTTPVDSNSPVITSTE---VSSSPTPAEGTSMPTSTYTEGRTPLTSITVRTTPVASSA 1706
Query: 1330 ASNL------------VSTQYTSVPTPSIGNNLPNLSTSSVLIP----PMGINNRFPSEK 1373
S L ST+ S PT S G ++PN + S P P+ SE
Sbjct: 1707 ISTLSTTPVDNSTPVTTSTEARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEA 1766
Query: 1374 IAIPG--------------SEEQATVSMGTTVRAALSCSDSVAVTDSLVAHPTVAMFTGN 1419
+ + T + GT++ + +T + V+H VA +
Sbjct: 1767 STLSATPIDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEAS 1826
Query: 1420 MLTINSYDS-PPKLSAESLDKNSGPRNRADNSGKPQQPPGGFAPAAINRSIPCKVIVDHS 1478
L+ DS P +++ ++ + P A+ + P + A SIP S
Sbjct: 1827 TLSTTPVDSNSPVVTSTAVSSSPTP---AEGTSIATSTPSEGSTAL--TSIPVSTTTVAS 1881
Query: 1479 TTLTSSLSLTVSVESSEAS--LDLQGRPVRTEASVQPVACPQVSVISRPEPVANEGIDHS 1536
+ T++LS T +V S+ + + P + S P + P+ RP P+ + I S
Sbjct: 1882 SE-TNTLSTTPAVTSTPVTTYAQVSSSPTTADGSSMPTSTPRE---GRP-PLTS--IPVS 1934
Query: 1537 STFIAASAAKQDSKTLPATCTSLRELPLVPDKLNEPTAPSHNFAEQARGPAPFKSEADTT 1596
+T +A+S S TL T T P + S A+ P P SE T
Sbjct: 1935 TTTVASSEINTLSTTLADTRT--------PVTTYSQASSSPTTADGTSMPTPAYSEGSTP 1986
Query: 1597 CSNQYNPSNRICWNDDGMRSTGQPLVTHSGSSKQKEYLEQSCPKAIKTEHANYLNVSELH 1656
++ + + ++ ST P+ T + ++ E S P A ++
Sbjct: 1987 LTSMPLSTTLVVSSEASTLST-TPVDTSTPATTSTE--GSSSPTT-----AGGTSIQTST 2038
Query: 1657 PRNLVTNVA-LPVKSELHEADKGFRMDTEDFPGPELPPPAAEGASSVQQTQNMKASTSSP 1715
P T +A +PV + L + +G + T + E ASS + + S+P
Sbjct: 2039 PSERTTPLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTE-ASSSATAEGSSMTISAP 2097
Query: 1716 MEEAISLATDALKRVPGAGSSGCRLSS--VEANNPLV--TQLLQGNLPLEKVLPQPRLGA 1771
E + L + L P A LS+ V++N+P++ T++ +P E Q +
Sbjct: 2098 SEGSPLLTSIPLSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPIPTEGTSMQTSTYS 2157
Query: 1772 KLEINRLPLPLQTTSVGKTAPERNVEIPPSSPNP 1805
+P+ TT V +A P + P
Sbjct: 2158 DRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTP 2191
Score = 114 bits (285), Expect = 1e-24
Identities = 305/1412 (21%), Positives = 520/1412 (36%), Gaps = 227/1412 (16%)
Query: 541 DSLIPSTSSMTHVSDTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMELQSDPEE 600
D P T+S S ES T +++ + T +S+ + + L + P E
Sbjct: 183 DMSTPLTTSTQASSSPTTPESTTIPKSTNSEGSTPLTSMPASTMKVASSEAITLLTTPVE 242
Query: 601 QLSENACISETSFSSESPEGACTSLPSP-GGETQST------------------------ 635
+ ++ S S + EG S +P GG T T
Sbjct: 243 ISTPVTISAQASSSPTTAEGPSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAAT 302
Query: 636 -------SEESCTPASLETTFCSEVSSTENTDKYNQRNSTDENFHASLMS--EISPISTS 686
+E S +P + E T + TE + ++ S MS I+P+ TS
Sbjct: 303 NIPVITSTEASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSITPVDTS 362
Query: 687 PEISEASLMSNLPLTSEASPVSNLPLTSETSPMSDLPLTSETSSVSSMLLTSETTFVSSL 746
++ ++ S+LP T+EA+ + L+ ++P++++P++ + ++ +SE + S++
Sbjct: 363 TLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTNMPVS------TILVASSEASTTSTI 416
Query: 747 PLPSETSPISNSSINERMAHQQRKSPSVSEEPLSPQKDESSATAKPLGENLTSQQKNLSN 806
P+ S+T + A + SP+ +E D S AT+ P + +S
Sbjct: 417 PVDSKTFVTT--------ASEASSSPTTAE-------DTSIATSTPSEGSTPLTSMPVST 461
Query: 807 TPEPIIMSSSSIAPEAFPSEDLHNKTLSQQTCKSHVDTE-KPYPASIPELASTEM--IKV 863
TP + SS + P + T S + S E P S P ST + + V
Sbjct: 462 TP---VASSEASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSV 518
Query: 864 KNHSVLQRTEKKVLPSPLELS--VFSEGTDNKGNELPSAKLQDKQYISSVDKAPFSEGSR 921
V + +P++ S V + + + P +S+ + SEGS
Sbjct: 519 STMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEG--------TSIPTSTPSEGST 570
Query: 922 NKTHKQGSTQSRLETSHTSKSSEPSKSPDGIRNESRDSEISKRKTAEQHSFGICKEKRAR 981
T+ ST+ + + ++ S+ P+ S + S S S E+
Sbjct: 571 PLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTT 630
Query: 982 IED-DQSTRNISSSSPPEKEQPPREEPRVPPLKIQLSKIGPPFIIKSQPVSKPESRASTS 1040
I ST ++SS P + + + S P S ++
Sbjct: 631 ITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPL 690
Query: 1041 TSV--------SGGRNTGARTLADIKARAQQARAQREAAAAAAVAAAASIVSGAMGSPGE 1092
TS+ S +T + T D + EA+++ A AS+ + +P E
Sbjct: 691 TSMPVNTTLVASSEASTLSTTPVD---TSTPVTTSTEASSSPTTADGASMPT---STPSE 744
Query: 1093 GGKTRTLAHIKEQTKAKLFAKHQARAHL-----FQTSKETRLPP--------PLSS-KEG 1138
G T + + A + L TS E P P+S+ EG
Sbjct: 745 GSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEG 804
Query: 1139 PP---NLEVSSTPETKMEGSTGVIIVNPNCRSPSNKSAHLRETTTVLQQSLNP------- 1188
P ++ VS TP T E ST + + SP S + + T + + P
Sbjct: 805 SPLLTSIPVSITPVTSPEAST-LSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEG 863
Query: 1189 ----SKLPETAT--------DLSVHSSDENIPVSHLSEKIVSSTSSENSSVPMLFNKNSV 1236
+ +P + T LS D + PV++ +E S T+SE +S+P S
Sbjct: 864 RTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMP-----TST 918
Query: 1237 PVSVCSTAISGAIKEHPFVSSVDKSSVLMSVD-SANTTISACNISMLKTIQG----TDTP 1291
P + S P VSS ++ VD S T S S T +G T TP
Sbjct: 919 PGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTP 978
Query: 1292 CIAIIPKCIESTPIS----ATTEGSSISSS-MDDKQLLISSSSASNLVST-QYTSVP--T 1343
P + STP+S A +E S++S++ +D L +S+ AS+ T + TS+P T
Sbjct: 979 SEGTTP--LTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTST 1036
Query: 1344 PSIGN----NLPNLSTSSVLIPPMGINNRFPSEKIAIPGSEEQA----TVSMGTTVRAAL 1395
PS G+ +P +ST+ V + P++ + QA T + GT++ +
Sbjct: 1037 PSEGSTPLTRMP-VSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTST 1095
Query: 1396 SCSDSVAVTDSLVAHPTVAMFTGNMLTINSYDSPPKLSAESLDKNSGPRNRADNSGKPQQ 1455
S +T V+ V + L+ D+ ++ S + +S P A+ + P
Sbjct: 1096 YSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTT-STEASSSP-TTAEGTSIPTS 1153
Query: 1456 PPG-GFAPAAINRSIPCKVIVDHSTTLT-----SSLSLTVSVESS--------------- 1494
PP G P A V+ + TL+ S + S E+S
Sbjct: 1154 PPSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTST 1213
Query: 1495 --EASLDLQGRPVRTEASVQPVACPQVSVISRPEPVANEGIDHSSTFIAASAAKQDSKTL 1552
E S L PVR PVA + S +S PV +S ++S + +L
Sbjct: 1214 PGERSTPLTSMPVRH----TPVASSEASTLS-TSPVDTSTPVTTSAETSSSPTTAEGTSL 1268
Query: 1553 PATCTS-----LRELPLVPDKLNEPTAP--------------SHNFAEQARGPAPFKSEA 1593
P + TS L +P+ + P A + N + PA S
Sbjct: 1269 PTSTTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMP 1328
Query: 1594 DTTCSNQYNPSNRICWNDDGMRSTGQPLV--THSGSSKQKEYLEQSCPKAIKTEHANYLN 1651
+T S P I N + S+ ++ T +S ++C +E + N
Sbjct: 1329 TSTYSEGRTPLTSIPVNTTLVASSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPN 1388
Query: 1652 VSELHPRNLVTNVAL---PVKSELHEADKGFRMDTEDFPGPELPPPAAEGASSVQQTQNM 1708
+ +T++ + PV S +DT PG +AE SS + +
Sbjct: 1389 SNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTST-PG----TTSAEATSSPTTAEGI 1443
Query: 1709 KASTSSPMEEAISLATDALKRVPGAGSSGCRLSS--VEANNPLVTQLLQGNLPLEKVLPQ 1766
TS+P E L + + P A S LS+ V++N+P+VT + P
Sbjct: 1444 SIPTSTPSEGKTPLKSIPVSNTPVANSEASTLSTTPVDSNSPVVTSTAVSS------SPT 1497
Query: 1767 PRLGAKLEINR--------LPLPLQTTSVGKT 1790
P G + I+ +P+ TT+V +
Sbjct: 1498 PAEGTSIAISTPSEGSTALTSIPVSTTTVASS 1529
Score = 114 bits (284), Expect = 1e-24
Identities = 287/1344 (21%), Positives = 485/1344 (36%), Gaps = 220/1344 (16%)
Query: 477 SEEAESLTNSHEEPQIAPPEDNLESCVMMNDVLETLPHIEVKIEGKSESPQEEMTVVIDQ 536
+E + S T I+ P + S ++ + L T P + S +P + + VI
Sbjct: 2079 TEASSSATAEGSSMTISAPSEG--SPLLTSIPLSTTPVASPEASTLSTTPVDSNSPVITS 2136
Query: 537 LEVCDSLIPST-SSMTHVSDTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMELQ 595
EV S IP+ +SM + ++ + T++ ST + + + S
Sbjct: 2137 TEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAIS----------------- 2179
Query: 596 SDPEEQLSENACISETSFSSESPEGACTSLPSPGGETQSTSEESCTPASLETTFCSEVSS 655
+S T + +P T S ++ TS + TP+ T F S S
Sbjct: 2180 -----------TLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVS 2228
Query: 656 TENTDKYNQRNSTDENFHASLMSEISPISTSPEISEASLMSNLPLTSEASPVSNLPLTSE 715
T T E AS +S +P+ TS ++ ++ ++ P T+E + + L+
Sbjct: 2229 TMPV-------VTSE---ASTLS-ATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEG 2277
Query: 716 TSPMSDLPLT------SETSSVSSMLLTSETTFVSSL------PLPSETS-PISNSSI-N 761
T+P++ +P++ SE S++S+ + S T F +S P TS P S SS N
Sbjct: 2278 TTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGN 2337
Query: 762 ERMAHQQRKSPSVSEEPLSPQKDESSATAKPLGENLTSQQKNLSNTPEPIIMSSSSIAPE 821
+ + V+ S + T+ P+ SQ + T + M +S+ +
Sbjct: 2338 TPLTRMPVSTTMVASFETSTLSTTPADTSTPV--TTYSQAGSSPTTADDTSMPTSTYSEG 2395
Query: 822 AFPSEDLHNKTLSQQTCKSHVDTEKPYPASIPELASTEMIKVKNHSVLQRTEKKVLPSPL 881
+ P + T+ + ++ + P S P STE S E +P+
Sbjct: 2396 STPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEA-----SSSPTTAEGTSIPT-- 2448
Query: 882 ELSVFSEGTDNKGNELPSAKLQDKQYISSVDKAPFSEGSRNKTHKQGSTQSRLETSHTSK 941
S SEGT L S + +SS G+ + T ST T+ T
Sbjct: 2449 --SPPSEGT----TPLASMPVSTTPVVSS------EAGTLSTTPVDTSTPM---TTSTEA 2493
Query: 942 SSEPSKSPDGIRNESRDSEISKRKTAEQHSFGICKEKRARIEDDQSTRNISSSSP----- 996
SS P+ + D + S SE S T+ S A ST + S+SP
Sbjct: 2494 SSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPEA---STLSTTPVDSNSPVVTST 2550
Query: 997 PEKEQPPREEPRVPPLKIQLSKIGPPFIIKSQPVSKPESRASTSTSVSGGRNTGARTLAD 1056
E P P ++S PVS +S ++++S T T
Sbjct: 2551 EISSSATSAEGTSMPTSTYSEGSTP---LRSMPVSTKPLASSEASTLS---TTPVDTSIP 2604
Query: 1057 IKARAQQARAQREAAAAAAVAAAASIVSGAMGS------PGEGGKTRTLAHIKEQTKAKL 1110
+ + + + A + + S VS ++ S P + TL+ T+
Sbjct: 2605 VTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRT-- 2662
Query: 1111 FAKHQARAHLFQTSKETRLPPPLSSKEGPPNLEVS--STPETKMEGSTGVIIVNPNCRSP 1168
L TS T P + P STP T + ST ++ N +
Sbjct: 2663 ---------LVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVST-TLLANSEASTL 2712
Query: 1169 SNKSAHLRETTTVLQQSLNPSKLPETATDLSVH---SSDENIPVSHLSEKIVSSTSSENS 1225
S +T+T + S S P TA S+ SD + P++ + + SSE S
Sbjct: 2713 STTPV---DTSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPVASSEAS 2769
Query: 1226 SVPMLFNKNSVPVSVCSTAIS----GAIKEHPFVSSVDKSSVLMSVDSANTTISACNISM 1281
+V S+PV+ + A S + P + + S+ L S+ +T +++
Sbjct: 2770 TVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGT 2829
Query: 1282 LKTIQGTDTPCIAIIPKCIESTPISATTEGSSISSSMDDKQLLISSSSASNLVSTQYTSV 1341
L T DT STP++ +T+ SS ++ + + IS++S + + T
Sbjct: 2830 LSTTP-VDT-----------STPVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVS 2877
Query: 1342 PTPSIGNNLPNLSTSSVLIPPMGINNRFPSEKIAIPGSEE---QATVSMGTTVRAALSCS 1398
TP + LST+ V I + S E T + GT++ +
Sbjct: 2878 TTPVASSEASTLSTTPV------------DTSIPVTTSTEGSSSPTTAEGTSMPISTPSE 2925
Query: 1399 DSVAVTDSLVAHPTVAMFTGNMLTINSYD--SPPKLSAESLDKNSGPRNRADNSGKPQQP 1456
S +T LV+ VA + L+ D +P SAE+ S A+ + P
Sbjct: 2926 VSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEA----SSSPTTAEGTSMPIST 2981
Query: 1457 PGGFAPAAINRSIPCKVIVDHS------TTLTSSLSLTVSVESSEASLDLQGR--PVRTE 1508
PG + S+ + T +S +T S E+S + +G P+ T
Sbjct: 2982 PGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTP 3041
Query: 1509 A-----------SVQPVACPQVSVISRPEPVANEGIDHSSTFIAASAAKQDSKTLPATCT 1557
+ S PVA P+ S +S PV + +ST +++S + ++P +
Sbjct: 3042 SEGSTPLTSIPVSTTPVAIPEASTLS-TTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTY 3100
Query: 1558 SLRELPLVPDKLNEPTAPSHNFAEQARGPAPFKSEADTTCSNQYNPSNRICWNDDGMRST 1617
S PL ++ T P + A P + T S + + S T
Sbjct: 3101 SEGSTPLTGVPVS--TTPVTSSAISTLSTTPVDTSTPVTTSTEAHSS------PTTSEGT 3152
Query: 1618 GQPLVTHSGSSKQKEYLEQSCPKAIKTEHANYLNVSELHPRNLVTNVALPVKSELHEADK 1677
P T S S Y+ S + +E + T A PV +
Sbjct: 3153 SMPTSTPSEGSTPLTYMPVSTMLVVSSEDS--------------TLSATPVDT------- 3191
Query: 1678 GFRMDTEDFPGPELPPPAAEGASSVQQTQNMKASTSSPMEEAISLATDALKRVPGAGSSG 1737
P + A+S + TS+P E L + + P A S
Sbjct: 3192 ------------STPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEA 3239
Query: 1738 CRLSS--VEANNPLVTQLLQGNLP 1759
LS+ V++N PL T + P
Sbjct: 3240 SILSTTPVDSNTPLTTSTEASSSP 3263
Score = 110 bits (275), Expect = 2e-23
Identities = 281/1333 (21%), Positives = 483/1333 (36%), Gaps = 222/1333 (16%)
Query: 561 SETAVETSTPKIKTGSSSLEGQFPNEGIAIDMELQSDPEEQLSENACISETSFSSESPEG 620
+ TA T++ + L E +I+ + SD S +E+ +SES
Sbjct: 65 ANTATGTTSTNVVEPRMYLSCSTNPEMTSIESSVTSDTPGVSSTRMTPTESRTTSESTSD 124
Query: 621 ACTSLPSPGGETQSTSEESCTPASLETTFCSEVSSTENTDKYNQRNSTDENFHASLMSEI 680
+ T PS +T S + T + T +SST S + + ++
Sbjct: 125 STTLFPSSTEDTSSPTTPEGTDVPMSTPSEESISSTMAFVSTAPLPSFEAYTSLTYKVDM 184
Query: 681 S-PISTSPEISEASLMSNLPLTSEASPVSNLPLTSETSPMSDLPLTSETSSVSSMLLTSE 739
S P++TS + S + P T E++ + + ++P++ +P + T V+S SE
Sbjct: 185 STPLTTSTQASSS------PTTPESTTIPKSTNSEGSTPLTSMP--ASTMKVAS----SE 232
Query: 740 TTFVSSLPLPSETSPISNSSINERMAHQQRKSPSVSEEP----LSPQKDESSATAKPLGE 795
+ + P+ T P++ S+ Q SP+ +E P +P + T PL
Sbjct: 233 AITLLTTPVEIST-PVTISA-------QASSSPTTAEGPSLSNSAPSGGSTPLTRMPLSV 284
Query: 796 NL--TSQQKNLSNTPE----PIIMSS-SSIAPEAFPSEDLHNKTLSQQTCKSHVDTEKPY 848
L +S+ LS TP P+I S+ +S +P + T ++ +
Sbjct: 285 MLVVSSEASTLSTTPAATNIPVITSTEASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTM 344
Query: 849 PASIPELASTEMIKVKNHS-VLQRTEKKVLPSPLE-----LSVFSEGTDNKGNELPSAKL 902
P + E+++ + V + V TE LP+ E S SEG+ N S L
Sbjct: 345 PVATSEMSTLSITPVDTSTLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTIL 404
Query: 903 QDKQYISSVDKAPFSEGSRNKTHKQGST------QSRLETSHTSKSSEPSKSPDGIRNES 956
S+ P + T + S+ + + TS S+ S P S
Sbjct: 405 VASSEASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPV 464
Query: 957 RDSEISKRKTAEQHSFGICKEKRARIEDDQSTRNISSSSPPEKEQPPREEPRVPPLKIQL 1016
SE S T S + +T +SSSPP E
Sbjct: 465 ASSEASNLSTTPVDS-----------KTQVTTSTEASSSPPTAE---------------- 497
Query: 1017 SKIGPPFIIKSQPVSKPESRASTSTSVSGG----RNTGARTLADIKA-RAQQARAQREAA 1071
+ S P S P ++ TS+S ++ A TL+ + EA+
Sbjct: 498 --------VNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEAS 549
Query: 1072 AAAAVAAAASIVSGAMGSPGEGGKTRTLAHIKEQTKAKLFAKHQARAHLFQTSKETRLPP 1131
+++ SI + +P EG T + + + + T
Sbjct: 550 SSSTTPEGTSIPT---STPSEGSTPLTNMPVSTRL-------------VVSSEASTTSTT 593
Query: 1132 PLSSKEGPPNLEVSSTPETKMEGSTGVIIVNPNCRSPSNKSAHLRETTTVLQQSLNPSKL 1191
P S +S+ T EG++ S + TT+ S++ + +
Sbjct: 594 PADSNTFVTTSSEASSSSTTAEGTS------------MPTSTYSERGTTITSMSVSTTLV 641
Query: 1192 PET-ATDLSVHSSDENIPVSHLSEKIVSSTSSENSSVP-MLFNKNSVPVS---VCSTAIS 1246
+ A+ LS D N PV+ +E SST++E +S+P + + S P++ V +T ++
Sbjct: 642 ASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVA 701
Query: 1247 GAIKEHPFVSSVDKSS-VLMSVDSANTTISACNISMLKTIQGTDTPCIAIIPKCIESTPI 1305
+ + VD S+ V S +++++ +A SM T TP P + S P+
Sbjct: 702 SSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASM-----PTSTPSEGSTP--LTSMPV 754
Query: 1306 SAT----TEGSSISSSMDDKQLLISSSSASNL--VSTQYTSVPTPSIGNNLPNLSTSSVL 1359
S T +E S++S++ D I++S+ ++ +T+ TS+P + P L++ V
Sbjct: 755 SKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVS 814
Query: 1360 IPPMGINNRFPSEKIAIPGSEEQATVSMGTTVRAALSCSDSVAVTDSLVAH---PTVAMF 1416
I P+ + ++ + + V+ T V ++ + ++ ++ S + P +M
Sbjct: 815 ITPV---TSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMP 871
Query: 1417 TGNMLTINSYDSPPKLSAESLDKNSGPRNRADNSGKPQQPPGGFAPAAINRSIPCKVIVD 1476
L S S LS +D ++ N + P G S+P +
Sbjct: 872 VSTTLVATSAIS--TLSTTPVDTSTPVTNSTEARSSPTTSEG--------TSMPTSTPGE 921
Query: 1477 HSTTLTSSLSLTVSVESSEASLDLQGRPV--------RTEASVQPVACPQVSV-ISRPE- 1526
ST LTS T V SSEA L PV TEA+ P S+ S P
Sbjct: 922 GSTPLTSMPDSTTPVVSSEAR-TLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSE 980
Query: 1527 ---PVANEGIDHSSTFIAASAAKQ------DSKTLPATCTSLRELPLVPDKLNEPTA-PS 1576
P+ + + H T +A S A DS T T T P + + PT+ PS
Sbjct: 981 GTTPLTSTPVSH--TLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPS 1038
Query: 1577 HNFAEQARGPAP----FKSEADTTCSNQYNPSNRICWNDDGMRS------TGQPLVTHS- 1625
R P SE T + + S + S T P T+S
Sbjct: 1039 EGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSE 1098
Query: 1626 -------------------GSSKQKEYLEQSCPKAIKTEHANYLNVSE------LHPRNL 1660
S+ ++ S P TE ++ +E P
Sbjct: 1099 GSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPPSEG 1158
Query: 1661 VTNVA-LPVKSELHEADKGFRMDTEDFPGPELPPPAAEGASSVQQTQNMKASTSSPMEEA 1719
T +A +PV + L + + + T + E +S + TS+P E +
Sbjct: 1159 TTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERS 1218
Query: 1720 ISLATDALKRVPGAGSSGCRLSS--VEANNPLVTQLLQGNLPLEKVLPQPRLGAKLEINR 1777
L + ++ P A S LS+ V+ + P+ T + P
Sbjct: 1219 TPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSP-------------TTAEG 1265
Query: 1778 LPLPLQTTSVGKT 1790
LP TTS G T
Sbjct: 1266 TSLPTSTTSEGST 1278
Score = 108 bits (270), Expect = 6e-23
Identities = 300/1351 (22%), Positives = 493/1351 (36%), Gaps = 210/1351 (15%)
Query: 526 PQEEMTVVIDQLEVCDSLIPSTSSMTHVSDTEHKESETAVETSTPKIKTGSSSLEGQFPN 585
P M VV + + TS+ S TA TS P S+ EG P
Sbjct: 2226 PVSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPT----STLSEGTTPL 2281
Query: 586 EGIAIDMELQSDPE-EQLSENACISETSF------SSESPEGACTSLPSPGGETQSTSEE 638
I + L ++ E LS S T F SS P TS+P+ STS E
Sbjct: 2282 TSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPT------STSSE 2335
Query: 639 SCTP-----------ASLETTFCSEVSSTENTD--KYNQRNST-----DENFHASLMSEI 680
TP AS ET+ S + +T Y+Q S+ D + S SE
Sbjct: 2336 GNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEG 2395
Query: 681 S------PISTSPEIS-EASLMSNLPL-----------------TSEASPVSNLPLTSET 716
S P+ST P +S EAS S P+ T+E + + P + T
Sbjct: 2396 STPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGT 2455
Query: 717 SPMSDLPLTSETSSVSSMLLTSETTFV-SSLPLPSET----SPISNSSINERMAHQQRKS 771
+P++ +P+ S T VSS T TT V +S P+ + T SP + I ++ S
Sbjct: 2456 TPLASMPV-STTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPISTASEGS 2514
Query: 772 PSVSEEPLSPQKDESSATAKPLGENLTSQQKNLSNTPEPIIMSSSSIAPEAFPSEDLHNK 831
++ P+S ++ A P L++ + SN+P +++S+ I+ A +E
Sbjct: 2515 TLLTSIPVS-----TTPVASPEASTLSTTPVD-SNSP---VVTSTEISSSATSAE---GT 2562
Query: 832 TLSQQTCKSHVDTEKPYPASIPELASTEMIKVKNHSVLQRTEKKVLPSPLELSVFSEGTD 891
++ T + P S LAS+E + V +P S T
Sbjct: 2563 SMPTSTYSEGSTPLRSMPVSTKPLASSEASTLSTTPV-----DTSIPVTTSTETSSSPTT 2617
Query: 892 NKGNELP-SAKLQDKQYISS--VDKAPFSEGSRNKTHKQGSTQSRLETSHTSKSSEPSKS 948
K +P S + ++S V P + + L T+ T SS P+ +
Sbjct: 2618 AKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTA 2677
Query: 949 PDGIRNESRDSEISKRKTAEQHSFGICKEKRARIEDDQSTRNISSSSPPEKEQPPREEPR 1008
S E S T S + A ST + +S+P P
Sbjct: 2678 EGSSMPTSTPGERSTPLTNILVSTTLLANSEA---STLSTTPVDTSTPVTTSAEASSSPT 2734
Query: 1009 V---PPLKIQLSKIG----PPFIIKSQPVSKPESRASTSTSVSGGRNTGARTLADIKARA 1061
++I G ++ + PV+ E+ ++T+V +T +A +
Sbjct: 2735 TAEGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAV----DTSIPVTTSTEASS 2790
Query: 1062 QQARAQREAAAAAAVAAAASIVSG--AMGSPGEGGKTRTLAHIKEQTKAKLFAKHQARAH 1119
A+ + + + ++ ++ +P + TL+ T + +A +
Sbjct: 2791 SPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSS 2850
Query: 1120 LFQTSKETRLPPPLSSKEGP---PNLEVSSTPETKMEGSTGVIIVNPNCRSPSNKSAHLR 1176
T+ E + P ++ EG ++ VS+TP E ST +P + S
Sbjct: 2851 --PTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEAST-------LSTTPVDTSI--- 2898
Query: 1177 ETTTVLQQSLNPSKLPETATDLSVHSSDENIPVSHLSEKIVSSTSSENSSVPMLFNKNSV 1236
TT + S +P+ T+ +S S+ + P++ + V SE S++
Sbjct: 2899 PVTTSTEGSSSPTTAEGTSMPIST-PSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRT 2957
Query: 1237 PVSVCSTAISGAIKEH----PFVSSVDKSSVLMSVDSANTTISACNISML-KTIQGTDTP 1291
PV+ + A S P + ++ + L S+ + +++ S L +T T TP
Sbjct: 2958 PVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTP 3017
Query: 1292 C-----IAIIPKCIEST--PISATTEGSSISSSMDDKQLLISSSSASNL----------- 1333
+ P E T PIS +EGS+ +S+ ++ AS L
Sbjct: 3018 VTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPV 3077
Query: 1334 -VSTQYTSVPTPSIGNNLPNLSTSSVLIPPMGIN-NRFPSEKIAI-----PGSEEQATVS 1386
ST+ +S PTP+ G ++P + S P G+ + P AI + V+
Sbjct: 3078 VTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVT 3137
Query: 1387 MGTTVRAALSCSDSVAV---TDSLVAHPTVAMFTGNMLTINSYDSPPKLSAESLDKNSGP 1443
T ++ + S+ ++ T S + P M ML ++S DS LSA +D ++
Sbjct: 3138 TSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDS--TLSATPVDTSTPV 3195
Query: 1444 RNRADNSGKPQQPPGGFAPAAINRSIPCKVIVDHSTTLTSSLSLTVSVESSEASLDLQGR 1503
+ + + A SIP + T LTS V SSEAS+ L
Sbjct: 3196 TTSTEATS---------STTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASI-LSTT 3245
Query: 1504 PV--------RTEASVQPVACPQVSVISRPEPVANEG------IDHSSTFIAASAAKQDS 1549
PV TEAS P P S P +EG + S+T +A+S S
Sbjct: 3246 PVDSNTPLTTSTEASSSP---PTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLS 3302
Query: 1550 KTLPATCTSLRELPLVPDKLNEPTAPSHNFAEQARGPAPFKSEADTTCSNQYNPSNRICW 1609
T T T P + S A+ P SE T +N
Sbjct: 3303 TTPADTST--------PVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTN---------- 3344
Query: 1610 NDDGMRSTGQPLVTHSGSSKQKEYLEQSCPKAIKTE------HANYLNVSELHPRNLVTN 1663
M + P+V+ S+ ++ S P TE A ++ P T
Sbjct: 3345 ----MSFSTTPVVSSEASTLSTTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTP 3400
Query: 1664 VA-LPVKSELHEADKGFRMDTEDFPGPELPPPAAEGASSVQQTQNMKASTSSPMEEAISL 1722
+A +PV + + + + T L + E +SS + TS+ E + L
Sbjct: 3401 LASMPVSTTPVVSSEVNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPL 3460
Query: 1723 ATDALKRVPGAGSSGCRLSS--VEANNPLVT 1751
+ L P A S LS+ V+ + P+ T
Sbjct: 3461 SIMPLSTTPVASSEASTLSTTPVDTSTPVTT 3491
Score = 100 bits (249), Expect = 2e-20
Identities = 280/1396 (20%), Positives = 501/1396 (35%), Gaps = 183/1396 (13%)
Query: 549 SMTHVSDTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMELQSDPEEQLSENACI 608
S T ++ TE + + + ST + + EG + M S EE +S
Sbjct: 106 SSTRMTPTESRTTSESTSDSTTLFPSSTEDTSSPTTPEGTDVPMSTPS--EESISSTMAF 163
Query: 609 SET----SFSSESPEGACTSLPSPGGETQSTSEESCTPASLETTFCSEVSSTENTDKYNQ 664
T SF + + + +P + S TP S TT +S +T +
Sbjct: 164 VSTAPLPSFEAYTSLTYKVDMSTPLTTSTQASSSPTTPES--TTIPKSTNSEGSTPLTSM 221
Query: 665 RNSTDENFHASLMSEIS-PISTSPEISEASLMSNLPLTSEASPVSNLPLTSETSPMSDLP 723
ST + + ++ ++ P+ S ++ ++ S+ P T+E +SN + ++P++ +P
Sbjct: 222 PASTMKVASSEAITLLTTPVEISTPVTISAQASSSPTTAEGPSLSNSAPSGGSTPLTRMP 281
Query: 724 LTSETSSVSSMLLTSETTFVSSLPLPSETSPISNSSINERMAHQQRKSPSVSEEPLSPQK 783
L+ S S T +++P+ + T S+ + E + P+ + S
Sbjct: 282 LSVMLVVSSEASTLSTTPAATNIPVITSTEASSSPTTAEGTS-----IPTSTYTEGSTPL 336
Query: 784 DESSATAKPLGENLTSQQKNLSNTP-EPIIMSSSSIAPEAFP----SEDLHNKTLSQ-QT 837
+ A+ P+ TS+ LS TP + + ++S P + P + + TLS+ T
Sbjct: 337 TSTPASTMPVA---TSEMSTLSITPVDTSTLVTTSTEPSSLPTTAEATSMLTSTLSEGST 393
Query: 838 CKSHVDTEKPYPASIPELASTEMIKVKNHS-VLQRTEKKVLPSPLELSVFSEGTDNKGN- 895
+++ AS E ++T I V + + V +E P+ E + + T ++G+
Sbjct: 394 PLTNMPVSTILVAS-SEASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIATSTPSEGST 452
Query: 896 ELPSAKLQDKQYISSVDKAPFSEGSRNKTHKQGSTQSRLETSHTSKSSEPSKSPDGIRNE 955
L S + SS + +KT ST++ +S P+ +P
Sbjct: 453 PLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTP 512
Query: 956 SRDSEISKRKTAEQHSFGICKEK-RARIEDDQSTRNISSSSPPEKEQPPREEPRVPPLKI 1014
+S A + + S+ SSS+ PE P P +
Sbjct: 513 LTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPL 572
Query: 1015 QLSKIGPPFIIKSQPVSKPESRASTSTSVSGGRNTGARTLADIKARAQQARAQREAAAAA 1074
+ ++ S+ + + A ++T V+ + + +
Sbjct: 573 TNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTIT 632
Query: 1075 AVAAAASIVSGAMGSPGEGGKTRTLAHIKEQTKAKLFAKHQARAHLFQTSKETRLPPPLS 1134
+++ + ++V+ + S + + T+A + A TS T PL+
Sbjct: 633 SMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEA-TSSSTTAEGTSMPTSTYTEGSTPLT 691
Query: 1135 SKEGPPNL----EVSSTPETKMEGSTGVIIVNPNCRSPSNKSAHLRETTTVLQQSLNPSK 1190
S L E S+ T ++ ST V SP+ T+T + S +
Sbjct: 692 SMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTS 751
Query: 1191 LPETATDLSVHSSDENIPVSHLSEKIVSSTSSENSSVPMLFNKNSVPVSVCSTA----IS 1246
+P + T L S + + L +TS+E S P S+P+S S S
Sbjct: 752 MPVSKT-LLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTS 810
Query: 1247 GAIKEHPFVSSVDKSSVLMSVDSANTTISACNISMLKT-IQGTDTPCIAI------IPKC 1299
+ P S + VDS + ++ +S T +GT P +
Sbjct: 811 IPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSM 870
Query: 1300 IESTPISATTEGSSISSSMDDKQLLISSS--SASNLVSTQYTSVPTPSIG------NNLP 1351
ST + AT+ S++S++ D +++S + S+ +++ TS+PT + G ++P
Sbjct: 871 PVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMP 930
Query: 1352 NLSTSSVLIPPMGINNRFPSEKIAIPGSEE---QATVSMGTTVRAALSCSDSVAVTDSLV 1408
+ +T V ++ + S E T + GT++ + + +T + V
Sbjct: 931 DSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTPV 990
Query: 1409 AHPTVAMFTGNMLTINSYDSPPKLSAESLDKNSGPRNRADNSGKPQQPPGGFAP------ 1462
+H VA + L+ DS L+ S + +S P S P G P
Sbjct: 991 SHTLVANSEASTLSTTPVDSNTPLTT-STEASSPPPTAEGTSMPTSTPSEGSTPLTRMPV 1049
Query: 1463 -----------------------------------AAINRSIPCKVIVDHSTTLTSSLSL 1487
A S+P + ST LTS
Sbjct: 1050 STTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVS 1109
Query: 1488 TVSVESSEASLDLQGRPV--------RTEASVQPVACPQVSVISRP-----EPVANEGID 1534
T V SSEAS L PV TEAS P S+ + P P+A+ +
Sbjct: 1110 TRLVVSSEAS-TLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPV- 1167
Query: 1535 HSSTFIAASAAKQ------DSKTLPATCTSLRELPLVPDKLNEPTA-PSHNFAEQARGPA 1587
S+T + +S A DSKT AT T P + + PT+ P P
Sbjct: 1168 -STTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPV 1226
Query: 1588 PF----KSEADTTCSNQYNPSNRICWNDDGMRSTGQPLVTHSGSSKQKEYLE-QSCPKAI 1642
SEA T ++ + T P+ T + +S E S P +
Sbjct: 1227 RHTPVASSEASTLSTSPVD--------------TSTPVTTSAETSSSPTTAEGTSLPTST 1272
Query: 1643 KTEHANYLNVSELHPRNLVTNVALPVKSELHEADKGFRMDTE--DFPGPEL-------PP 1693
+E + L ++PV + L + + + T D GP + P
Sbjct: 1273 TSEGSTLL-------------TSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSP 1319
Query: 1694 PAAEGASSVQQT--QNMKASTSSPMEEAI--SLATDALKRVPGAGSSGCRLSSVEANNPL 1749
AEG S T + TS P+ + S A L P S+ S+ ++P
Sbjct: 1320 TPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILSTTPVDNSTPVTTSTEACSSPT 1379
Query: 1750 VTQ--------LLQGNLPLEKVLPQPRLGAKLEINRL-PLPLQTTSVGKTAPE------- 1793
++ +G PL + E + L P+ T++ G T+ E
Sbjct: 1380 TSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTT 1439
Query: 1794 -RNVEIPPSSPNPDGK 1808
+ IP S+P+ +GK
Sbjct: 1440 AEGISIPTSTPS-EGK 1454
Score = 97.1 bits (240), Expect = 2e-19
Identities = 254/1284 (19%), Positives = 434/1284 (33%), Gaps = 142/1284 (11%)
Query: 367 EESVKLTTGPNNAGAQSSSSCGT-SGLPVSAQTALAEQQPKSMKSPASPEPGFCATLCPM 425
E S LT+ P N +SS GT S PV T + K+ SP + E G +
Sbjct: 2807 ETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTST-KASSSPTTAE-GIVVPISTA 2864
Query: 426 VEIPPKDIMAELESEDILIPEESVIQEEIAEEVETSICECQDENHKTIPEFSEEAESLTN 485
E + + + E S + V+TSI + P +E +
Sbjct: 2865 SEGSTLLTSIPVSTTPVASSEASTLS---TTPVDTSIPVTTSTEGSSSPTTAEGTSMPIS 2921
Query: 486 SHEEPQI--------APPEDNLESCVMMNDVLETLPHIEVKIEGKSESPQEE---MTVVI 534
+ E P E+ + ++T + E S E M +
Sbjct: 2922 TPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPIST 2981
Query: 535 DQLEVCDSLIPSTSSMTHVSDTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMEL 594
S S+M S S T +TSTP + T + + EG I +
Sbjct: 2982 PGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTP-VTTSTEASSSPTTAEGTGIPIST 3040
Query: 595 QSDPEEQLS------------ENACISETSFSSESPEGACTSLPSPGGETQSTSEESCTP 642
S+ L+ E + +S T S SP T + S + TS T
Sbjct: 3041 PSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTY 3100
Query: 643 ASLETTFCS-EVSSTENTDKYNQRNSTDENFHASLMSEISPISTSPEISEASLMSNLPLT 701
+ T VS+T T ST ++ ++ + +SP SE + M +
Sbjct: 3101 SEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPS 3160
Query: 702 SEASPVSNLPLT------SETSPMSDLPLTSETSSVSSMLLTSETTFV-SSLPL--PSE- 751
++P++ +P++ SE S +S P+ + T +S TS TT +S+P PSE
Sbjct: 3161 EGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEG 3220
Query: 752 -----TSPISNSSINERMAHQQRKSPSVSEEPLSPQKDESSATAKPLGENLTSQQKNLSN 806
+ P+SN+ + A +P S PL+ + SS+ G ++ + + +
Sbjct: 3221 MTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGS 3280
Query: 807 TPEPIIMSSSSIAPEAFPSEDLHNKTLSQQTCKSHVDTEKPYPASIPELASTEMIKVKNH 866
TP ++S ++ S + + + + V T +S P T M
Sbjct: 3281 TP----LTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQASSSPPIADGTSM------ 3330
Query: 867 SVLQRTEKKVLPSPLELSVFSEGTDNKGNELPSAKLQDKQYISSVDKAPFSEGSRNKTHK 926
S +SEG+ N S S++ P + T
Sbjct: 3331 ---------------PTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTT-- 3373
Query: 927 QGSTQSRLETSHTSKSSEPSKSPDGIRNESRDSEISKRKTAEQHSFGICKEKRARIEDDQ 986
ST++ L + +S P+ SP +S + E
Sbjct: 3374 --STEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPV-------VSSEVNTLSTTPV 3424
Query: 987 STRNISSSSPPEKEQPPREEPRVPPLKIQLSKIGPPFIIKSQPVSKPESRASTSTSVSGG 1046
+ + ++S P E P P I+ S AST ++
Sbjct: 3425 DSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTPVD 3484
Query: 1047 RNTGARTLADIKARAQQARAQREAAAAAAVAAAASIVSGAMGSPGEGGKTRTLAHIKEQT 1106
+T T + + A + A + +P + TL+ +
Sbjct: 3485 TSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDS 3544
Query: 1107 KAKLFAKHQARAHLFQTSKET-RLPPPLSSKEGPPNLEVSSTPETKMEGSTGVIIVNPNC 1165
+ + QA + T R+ P + +SST T E ST
Sbjct: 3545 NTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEAST--------- 3595
Query: 1166 RSPSNKSAHLRETTTVLQQSLNPSKLPETATDLSVHSSDENIPVSHLSEKIVSSTSSENS 1225
PS S T QS + PE T S+ + P++ + S T SE
Sbjct: 3596 --PSTPSVDRSTPVTTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMPVSTTSVTISEAG 3653
Query: 1226 SVPMLFNKNSVPV----SVCSTAISGAIKEHPFVSSVDKSSVLMSVDSANTTISACNISM 1281
+ L S PV V S+ ++ P + + S+ L ++ + T +++ S
Sbjct: 3654 TASTLPVDTSTPVITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMPVSTTRVTSSEGST 3713
Query: 1282 LKTIQGTDTPCIAIIPKCIESTPISATTEGSSISSSMDDKQLLISSSSASNLVSTQYTSV 1341
L T P + STP++ +TE S S+++D + +S + + T
Sbjct: 3714 LST------------PSVVTSTPVTTSTEAISSSATLDSTTMSVSMPMEISTLGTTILVS 3761
Query: 1342 PTPSIGNNLPNLSTSSVLIPPMGINNRFPSEKIAIPGSEEQATVSMGTTVRAALSCSDSV 1401
TP P ST S+ ++ SE GS T+ TT+ + + S
Sbjct: 3762 TTPV--TRFPESSTPSIPSVYTSMSMTTASE-----GSSSPTTLEGTTTMPMSTTSERST 3814
Query: 1402 AVTDSLVAHPTVAMFTGNMLTINSYDSPPKLSAESLDKNSGPRNRADNSGKPQQPPGGFA 1461
+T L++ P M T++ +PP ++ L ++ G F+
Sbjct: 3815 LLTTVLIS-PISVMSPSEASTLS---TPPGDTSTPLLTST--------------KAGSFS 3856
Query: 1462 PAAINRSIPCKVIVDHSTTLTSSLSLTVSVESSEASLDLQGRPVRTEASVQP----VACP 1517
A +I + + ST LT+ L T S + P+ T + P + P
Sbjct: 3857 IPAEVTTIRISITSERSTPLTTLLVSTTLPTSFPGASIASTPPLDTSTTFTPSTDTASTP 3916
Query: 1518 QVSVISR-PEPVANEGIDHSSTFIAAS--AAKQDSKTLPATCTSLRELPLVPDKLNEPTA 1574
+ V + V EG +T S + PAT ++ + +LN P+
Sbjct: 3917 TIPVATTISVSVITEGSTPGTTIFIPSTPVTSSTADVFPATTGAVSTPVITSTELNTPST 3976
Query: 1575 PSHNFAEQARGPAPFKSEADTTCS 1598
S + F + A TT +
Sbjct: 3977 SSSSTTTSFSTTKEFTTPAMTTAA 4000
Score = 70.9 bits (172), Expect = 1e-11
Identities = 199/941 (21%), Positives = 344/941 (36%), Gaps = 102/941 (10%)
Query: 367 EESVKLTTGP-NNAGAQSSSSCGTSGLPVSAQTALAEQQPKSMKSPASPEPGFCATLCPM 425
E LT+ P +N SS + S PV + T L S SP + E T P
Sbjct: 3219 EGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEAS-SSPPTAEGTSMPTSTPS 3277
Query: 426 VEIPPKDIMAELESEDILIPEESVIQEEIAEEVETSICECQDENHKTIPEFSEEAESLTN 485
P M + + + E S + A+ TS + P ++ T+
Sbjct: 3278 EGSTPLTSMP-VSTTTVASSETSTLSTTPAD---TSTPVTTYSQASSSPPIADGTSMPTS 3333
Query: 486 SHEEPQIAPPEDNLESCVMMNDVLETLPHIEVKIEGKSESPQEEMTVVIDQLEVCDSLIP 545
++ E S + N T P + + S +P + T V E SL P
Sbjct: 3334 TYSEG----------STPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTSTEA--SLSP 3381
Query: 546 STSSMTHVSDTEHKESETAVET----STPKIKTGSSSLEGQFPNEGIAIDMELQSDPEEQ 601
+T+ T + + E T + + +TP + + ++L + + ++
Sbjct: 3382 TTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPVDSNTLVTTSTEASSSPT 3441
Query: 602 LSENACISETSFSSESPEGACTSLPSPGGETQSTSEESCTPASLET--TFCSEVSSTENT 659
++E + ++ S S + L + + S S TP T T S +S+ T
Sbjct: 3442 IAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTTSSPTNSSPTT 3501
Query: 660 DKYNQRNSTDENFHASLMSEISPISTSPEIS-EASLMSNLPLTSE-----ASPVSNLPLT 713
+ ++ ++ ++ + P+ST+P S EAS +S P+ S +S S+ P T
Sbjct: 3502 AEVTSMPTSTAGEGSTPLTNM-PVSTTPVASSEASTLSTTPVDSNTFVTSSSQASSSPAT 3560
Query: 714 SETSPMSDLPLTSETSSVSSMLLTSETTFVSSLPLPSETSPISNSSINERMAHQQRKSPS 773
+ + M + +SS+++MLL+S T+V+S + ++P + S + Q +P+
Sbjct: 3561 LQVTTMRMSTPSEGSSSLTTMLLSS--TYVTSSEASTPSTPSVDRSTPVTTSTQSNSTPT 3618
Query: 774 VSEE---PLSPQKDES--------SATAKPLGENLTSQQKNLSNTPEPII----MSSSSI 818
E P+S + S S T+ + E T+ + +T P+I +SSS +
Sbjct: 3619 PPEVITLPMSTPSEVSTPLTIMPVSTTSVTISEAGTASTLPV-DTSTPVITSTQVSSSPV 3677
Query: 819 APEAF------PSED---LHNKTLSQQTCKSHVDTEKPYPA---SIPELASTEMIKVKNH 866
PE PSE L +S S + P+ S P STE I +
Sbjct: 3678 TPEGTTMPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTPSVVTSTPVTTSTEAIS--SS 3735
Query: 867 SVLQRTEKKVLPSPLELSVFSEGTDNKGNELPSAKLQDKQYIS------SVDKAPFSEGS 920
+ L T V P+E+S GT + P + + S S+ SEGS
Sbjct: 3736 ATLDSTTMSV-SMPMEISTL--GTTILVSTTPVTRFPESSTPSIPSVYTSMSMTTASEGS 3792
Query: 921 RNKTHKQGSTQSRLETSHTSKSSEPSK--SPDGIRNESRDSEISKRK---------TAEQ 969
+ T +G+T + T+ + + SP + + S S +S + +
Sbjct: 3793 SSPTTLEGTTTMPMSTTSERSTLLTTVLISPISVMSPSEASTLSTPPGDTSTPLLTSTKA 3852
Query: 970 HSFGICKEK---RARIEDDQST--RNISSSSPPEKEQPPREEPRVPPLKIQLSKIGPPFI 1024
SF I E R I ++ST + S+ P PPL + F
Sbjct: 3853 GSFSIPAEVTTIRISITSERSTPLTTLLVSTTLPTSFPGASIASTPPLDTSTT-----FT 3907
Query: 1025 IKSQPVSKPESRASTSTSVS--GGRNTGARTLADIKARAQQARAQREAAAAAAVAAAASI 1082
+ S P +T+ SVS +T T+ + A A AV+ I
Sbjct: 3908 PSTDTASTPTIPVATTISVSVITEGSTPGTTIFIPSTPVTSSTADVFPATTGAVSTPV-I 3966
Query: 1083 VSGAMGSPGEGGKTRTLAHIKEQTKAKLFAKHQARAHLFQTSKETRLPPPLSSKEG---- 1138
S + +P + T + TK A L + T P ++ G
Sbjct: 3967 TSTELNTPSTSSSSTTTSF--STTKEFTTPAMTTAAPLTYVTMSTAPSTPRTTSRGCTTS 4024
Query: 1139 PPNLEVSSTPETKMEGSTGVIIVNPNCRSPSNKSAHLRETTTVLQQSLNPSKLPETATDL 1198
L +STP T +T + + PS ++H T S P ++T +
Sbjct: 4025 ASTLSATSTPHTSTSVTTRPVTPSSESSRPSTITSHTIPPTFPPAHSSTPPTTSASSTTV 4084
Query: 1199 SVHSSDENIPVSHLSEKIVSSTSSENSSVPMLFNKNSVPVS 1239
+ + + S + S + ++VP S P S
Sbjct: 4085 NPEAVTTMTTRTKPSTRTTSFPTVTTTAVPTNTTIKSNPTS 4125
Score = 49.3 bits (116), Expect = 4e-05
Identities = 115/529 (21%), Positives = 187/529 (35%), Gaps = 56/529 (10%)
Query: 542 SLIPSTSSMTHVSDTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMELQSDPEEQ 601
S +P +S ++ T+ S E +T I T S EG P + + S
Sbjct: 3656 STLPVDTSTPVITSTQVSSSPVTPEGTTMPIWTPS---EGSTPLTTMPV-----STTRVT 3707
Query: 602 LSENACISETSFSSESPEGACTSLPSPGGETQSTSEESCTPASLETTFCSEVSSTENTDK 661
SE + +S S + +P T S ST+ P + T + + ST +
Sbjct: 3708 SSEGSTLSTPSVVTSTPVTTSTEAISSSATLDSTTMSVSMPMEISTLGTTILVSTTPVTR 3767
Query: 662 YNQRN--STDENFHASLMSEISPISTSPEISEASLMSNLPLTSEASPVSNLPLTSETSPM 719
+ + + S + + M+ S S+SP E + + TSE S + L S S M
Sbjct: 3768 FPESSTPSIPSVYTSMSMTTASEGSSSPTTLEGTTTMPMSTTSERSTLLTTVLISPISVM 3827
Query: 720 SDLP---LTSETSSVSSMLLTSETTFVSSLPLPSETSPISNSSINERMAHQQRKSPSVSE 776
S L++ S+ LLTS T S +P+E + I S +ER S +
Sbjct: 3828 SPSEASTLSTPPGDTSTPLLTS--TKAGSFSIPAEVTTIRISITSERSTPLTTLLVSTTL 3885
Query: 777 EPLSPQKDESSATAKPLGENLTSQQKNLSNTPEPIIMSSSSIAPEAFPSEDLHNKTLSQQ 836
P S A+ PL + T+ + P I +++I+ T+
Sbjct: 3886 PTSFP--GASIASTPPL-DTSTTFTPSTDTASTPTIPVATTISVSVITEGSTPGTTIFIP 3942
Query: 837 TCKSHVDTEKPYPA-----SIPELASTEMIKVKNHSVLQRTEKKVLPSPLELSVFSEGTD 891
+ T +PA S P + STE+ PS S + +
Sbjct: 3943 STPVTSSTADVFPATTGAVSTPVITSTELNT---------------PSTSSSSTTTSFST 3987
Query: 892 NKGNELPSAKLQDKQYISSVDKAPFSEGSRNK-THKQGSTQSRLETSHTSKSSEPSKSPD 950
K P+ ++ AP + + ++ ST S T HTS S
Sbjct: 3988 TKEFTTPAMTTAAPLTYVTMSTAPSTPRTTSRGCTTSASTLSATSTPHTSTSVTT----- 4042
Query: 951 GIRNESRDSEISKRKTAEQHSFGICKEKRARIEDDQSTRNISSSSPPE-------KEQPP 1003
R + SE S+ T H+ A +T S++ PE + +P
Sbjct: 4043 --RPVTPSSESSRPSTITSHTIPPTFPP-AHSSTPPTTSASSTTVNPEAVTTMTTRTKPS 4099
Query: 1004 REEPRVPPLKIQLSKIGPPFIIKSQPVSKPESRASTSTSVSGGRNTGAR 1052
P + + + IKS P S P +T+ G +NT +R
Sbjct: 4100 TRTTSFPT--VTTTAVPTNTTIKSNPTSTPTVPRTTTCFGDGCQNTASR 4146
>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
Length = 5478
Score = 87.8 bits (216), Expect = 1e-16
Identities = 241/1140 (21%), Positives = 387/1140 (33%), Gaps = 135/1140 (11%)
Query: 546 STSSMTHVSDTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMELQSDPEEQLSEN 605
+T ++ S T + S + ET+ T ++S+ G+ P S P +
Sbjct: 1292 TTPGLSEESTTVYSSSRGSTETTVFPHST-TTSVHGEEPTT-------FHSRPAS--THT 1341
Query: 606 ACISETSFSSESPEGACTSLPSPGGETQSTSEESCTPASL---ETTFCSEVSSTENTDKY 662
+E S +S E + T+ P TQ+ + T A L TTF S ST K
Sbjct: 1342 TLFTEDSTTSGLTEES-TAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGT--KL 1398
Query: 663 NQRNSTDENFHASLMSEISPISTSPEISEASLMSNLPLTSEASPVSNLPLTSETSPMSDL 722
+ ST + L+ E +P SP +E + + P T S S TS SP + L
Sbjct: 1399 SPARSTT----SGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATL 1454
Query: 723 -PLTSETSSVSSMLLTSE----TTFVSSLPLPSETSPISNSSINERMAHQQRKSPSVSEE 777
P T+ +S VS TS +T ++ P + TS +S S +E
Sbjct: 1455 SPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTT------SHSSQGSTEA 1508
Query: 778 PLSPQKDESSATAKPLGENLTSQQKNLSNT-----PEPIIMSS----------------S 816
LSP S TA LG+ T+ + +T P+ I S +
Sbjct: 1509 TLSP----GSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHT 1564
Query: 817 SIAPEAFPSEDLHNKTLSQQTCKSHVDTEKPYPASIPELASTEMIKVKNHSVLQRT---- 872
++ P + S L ++ + Q+ S DT P + A+ + HS T
Sbjct: 1565 TLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGT---TAAPVEVSTTYHSRPSSTPTTH 1621
Query: 873 ---EKKVLPSPLELSVFSEGTDNKGNELPSAKLQDKQYISSVDKAPFSEGSRNKTHKQGS 929
L E + G L + + +P S GS T GS
Sbjct: 1622 FSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGS 1681
Query: 930 TQSR-LETSHTSKSSEPSKSPDGIRN--ESRDSEISKRKTAEQHSFGICKEKRARIEDDQ 986
T + L T+ S P +SPD + + S +S+ T G
Sbjct: 1682 TTTAGLSEKSTTFYSSP-RSPDTTLSPASTTSSGVSEESTTSHSRPG--STHTTAFPGST 1738
Query: 987 STRNISSSSPPEKEQPPREEPRVPPLKIQLSKIGP-PFIIKSQPVSKPESRASTSTSVSG 1045
+ +S S P + + P S +GP S P S + +T+ SG
Sbjct: 1739 TMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASG 1798
Query: 1046 --------GRNTGA--RTLADIKARAQQARA-------QREAAAAAAVAAAASIVSGAMG 1088
+TG+ TL+ + +Q + + A ++ V +
Sbjct: 1799 LLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTT 1858
Query: 1089 SPGEGGKTRTLAHIKEQTKAKLFAKHQARAHLFQTSKETRLPPPLSSKEGPPNLEVSSTP 1148
S G T T H + ++ H + T P S+ G L ST
Sbjct: 1859 SHGSPSSTPT-THFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSG---LVEESTA 1914
Query: 1149 ETKMEGSTGVI----IVNPNCRSPSNKSAHLRETTTVLQQSLNPSKLPETATDLSVHSSD 1204
GST + + RS ++++H T T+ S L E T S HSS
Sbjct: 1915 YHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPT--SYHSSP 1972
Query: 1205 ENIPVSHLSEKIVSSTSSENSSVPMLFNKNSVPVSVCSTAISGAIKEHPFVSSVDKSSVL 1264
+ +H + +S SE S+ + + + + + + + S + S+
Sbjct: 1973 GSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSME 2032
Query: 1265 MSVDSANTTISACNISMLKTIQGTDTPCIAIIPKCIESTPIS--ATTE----GSSISSSM 1318
+ +TT + +P + P S+ +S +TT GS+ +++
Sbjct: 2033 TTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAF 2092
Query: 1319 DDKQLL-----ISSSSASNLVSTQYTSVPTPSIGNNLPNLSTSSVLIPPMGINNRFPSEK 1373
D S++S S+ ST T +P + + ST+S P P
Sbjct: 2093 PDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGST 2152
Query: 1374 IAIPGSEEQATVSMGTTVRAALSCSDSVAVTDSLVAHPTVAMFTGNMLTINS--YDSPPK 1431
A+ +E T DS + + A V TG+ T S + P
Sbjct: 2153 TALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPG 2212
Query: 1432 LSAESLDKNSGPRNRADNSGKPQQPPGGFAPAAINR-------SIPCKVIVDHSTTLTSS 1484
L ES + P A P P AP + S P STT S
Sbjct: 2213 LQGESTAFQTHP---ASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHS 2269
Query: 1485 LSLTVSVESSEAS--------LDLQGRPVRTEASVQPVACPQVSVISRPEPVANEGIDHS 1536
T+ S +AS GR T + + P + + P G+ +
Sbjct: 2270 EKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISP---GSTEITTLPGSTTTPGLSEA 2326
Query: 1537 STFIAASAAKQDSKTLPATCTSLRELPLVPDKLNEPTAPSHNFAEQARGPAPFKSEADTT 1596
ST +S + PA+ TSL ++P +H+ A P SE TT
Sbjct: 2327 STTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQP-GSTHSTVSPASTTTPGLSEESTT 2385
Score = 87.8 bits (216), Expect = 1e-16
Identities = 237/1116 (21%), Positives = 384/1116 (34%), Gaps = 122/1116 (10%)
Query: 546 STSSMTHVSDTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMELQSDPEEQLSEN 605
ST S + E T V +S+P S+ FP + +P S
Sbjct: 3924 STVSPASTTTPGLSEESTTVYSSSP-----GSTETTVFPRS--TTTSVRREEPTTFHSRP 3976
Query: 606 ACISETSFSSESPEGACT----SLPSPGGETQSTSEESCTPASL---ETTFCSEVSSTEN 658
A T F+ +S T + P TQ+ + T A L TTF S ST
Sbjct: 3977 ASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGT 4036
Query: 659 TDKYNQRNSTDENFHASLMSEISPISTSPEISEASLMSNLPLTSEASPVSNLPLTSETSP 718
K + ST + L+ E +P SP +E + + P T S S TS SP
Sbjct: 4037 --KLSPARSTT----SGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSP 4090
Query: 719 MSDL-PLTSETSSVSSMLLTSE----TTFVSSLPLPSETSPISNSSINERMAHQQRKSPS 773
+ L P T+ +S VS TS +T ++ P + TS +S S
Sbjct: 4091 DATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTT------SHSSQG 4144
Query: 774 VSEEPLSPQKDESSATAKPLGENLTSQQKNLSNT-----PEPIIMSS------------- 815
+E LSP S TA LG+ T+ + +T P+ I S
Sbjct: 4145 STEATLSP----GSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTG 4200
Query: 816 ---SSIAPEAFPSEDLHNKTLSQQTCKSHVDT--EKPYPASIP-ELASTEMIKVKNHSVL 869
+++ P + S L ++ + Q+ S DT P ++P E+++T + +
Sbjct: 4201 SLHTTLTPASSTSTGLQEESTTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTT 4260
Query: 870 Q-RTEKKVLPSPLELSVFSEGTDNKGNELPSAKLQDKQYISSVDKAPFSEGSRNKTHKQG 928
L E + G L + + +P S GS T G
Sbjct: 4261 HFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPG 4320
Query: 929 STQSR-LETSHTSKSSEPSKSPDGIRN--ESRDSEISKRKTAEQHSFGICKEKRARIEDD 985
ST + L T+ S P +SPD + + S +S+ T G
Sbjct: 4321 STTTAGLSEKSTTFYSSP-RSPDTTLSPASTTSSGVSEESTTSHSRPG--SMHTTAFPSS 4377
Query: 986 QSTRNISSSSPPEKEQPPREEPRVPPLKIQLSKIGP-PFIIKSQPVSKPESRASTSTSVS 1044
+ +S S P + + P S +GP S P S + +T+ S
Sbjct: 4378 TTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTAS 4437
Query: 1045 G--------GRNTGA--RTLADIKARAQQARA-------QREAAAAAAVAAAASIVSGAM 1087
G +TG+ TL+ + +Q + + A ++ V +
Sbjct: 4438 GLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELST 4497
Query: 1088 GSPGEGGKTRTLAHIKEQTKAKLFAKHQARAHLFQTSKETRLPPPLSSKEGPPNLEVSST 1147
S G T T H + ++ H + T P S+ G L ST
Sbjct: 4498 TSHGSPSSTPT-THFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSG---LVEEST 4553
Query: 1148 PETKMEGSTGVIIV----NPNCRSPSNKSAHLRETTTVLQQSLNPSKLPETATDLSVHSS 1203
GST + + R + ++H T T+ S L E T S HSS
Sbjct: 4554 TYHSSPGSTQTMHFPESNTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPT--SYHSS 4611
Query: 1204 DENIPVSHLSEKIVSSTSSENSSVPMLFNKNSVPVSVCSTAISGAIKEHPFVSSVDKSSV 1263
+ +H + +S SE S+ S S +G I + + +SV
Sbjct: 4612 PGSTATTHFPDSSTTSGRSEEST-----------ASHSSQDATGTI----VLPARSTTSV 4656
Query: 1264 LMSVDSANTTISACNISMLKTIQGTDTPCIAIIPKCIESTPISATTEGSSISSSMDDKQL 1323
L+ +S + IS+ ++ T TP ++ S+P S T S SS+ +
Sbjct: 4657 LLG-ESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPSSTPTTHFSASSTTLGRS- 4714
Query: 1324 LISSSSASNLVSTQYTSVPTPSIGNNLPNLSTSSVLIPPMGINNRFPSEKIAIPGSEEQA 1383
S++ S+ V+T T P S + L ST+ P FP A SEE
Sbjct: 4715 EESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESR 4774
Query: 1384 TVSMGTTVRAALSCSDSVAVTDSLVAHPTVAMFTGNMLTINSYDSPPKLSAESLDKNSGP 1443
T TT + S + T +LV PT + + + S S ++++
Sbjct: 4775 TSHSSTT----HTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRS-EESTAS 4829
Query: 1444 RNRADNSGKPQQPPGGFAPAAINRSIPCKVIVDHSTTLTSSLSLTVSVESSEASLDLQGR 1503
+ D +G P I S + T +S + T + + L R
Sbjct: 4830 HSSPDTNGITPLPAHFTTSGRIAESTTFYISPGSMETTLASTATTPGLSAKSTILYSSSR 4889
Query: 1504 PVRTEASVQPVACPQVSVISRPEPVANEGIDHSSTFIAASAAKQDSKTLPATCTSLRELP 1563
+ ++ P + S+ P + ++ ST A A + L T+ P
Sbjct: 4890 --SPDQTLSPASMTSSSISGEPTSLYSQA---ESTHTTAFPASTTTSGLSQESTTFHSKP 4944
Query: 1564 -LVPDKLNEPTAPSHNFAEQARGPAPFKSEADTTCS 1598
L+ + + +FA++ P A +T S
Sbjct: 4945 GSTETTLSPGSITTSSFAQEFTTPHSQPGSALSTVS 4980
Score = 87.0 bits (214), Expect = 2e-16
Identities = 262/1305 (20%), Positives = 449/1305 (34%), Gaps = 193/1305 (14%)
Query: 395 SAQTALAEQQPKSMKSPASPEPGFCATL--CPMVEIPPKDIMAELESEDILIPEESVIQE 452
S + L E+ SPAS + G ATL + E + + L P S
Sbjct: 1348 STTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSG 1407
Query: 453 EIAEEVETSICECQDE-----NHKTIPEFSEEAESLTNSHEEPQ--IAPPEDNLESCVMM 505
+ E + + E T P SE++ + S P ++P
Sbjct: 1408 LVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEE 1467
Query: 506 NDVLETLP---HIEVKIEG--KSESPQEEMTVVIDQLEVCDSLIP---STSSMTHVSDTE 557
+ + P H + S+ QE T Q +L P + SS+ S T
Sbjct: 1468 SSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTF 1527
Query: 558 HKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMELQSDPEEQLSENACISETSFSSES 617
H T P S +E P + P S +A + E S + +S
Sbjct: 1528 HSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPAS--STSAGLQEESTTFQS 1585
Query: 618 PEGACTSLPSPGGETQSTSEESCT----PASLETTFCSEVSST-----ENTDKYNQRNST 668
+ + PSP G T + E S T P+S TT S S+T E+T ++ +T
Sbjct: 1586 WPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGAT 1645
Query: 669 DENFHASLMSE---ISPISTSPEISEASLMSNLPLTSEASPVSNLPLTSETSPMSDLPLT 725
+ + + +TSP S ++ + LP ++ + +S T +SP S
Sbjct: 1646 GTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTL 1705
Query: 726 SETSSVSSMLLTSETTFVSSLPLPSETSPISNSSINERMAHQ---QRKSPSVSEEPLSPQ 782
S S+ SS ++ E+T S P + T+ S+ ++ + SP ++ LSP
Sbjct: 1706 SPASTTSSG-VSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSP- 1763
Query: 783 KDESSATAKPLGENLTSQQKNLSNTPEPIIMSSSSIAPEAFPSEDLHNKTLSQQTCKS-- 840
S TA LG T+ + +T ++ +++ + S +H+ T S T S
Sbjct: 1764 ---GSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPA 1820
Query: 841 -------HVDTEKPYPAS-----IPELASTEMIKVKNHSVLQRTEKKVLPSPLELSVFSE 888
T + +P+S P ++ +++ T PS + FS
Sbjct: 1821 GSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELS-------TTSHGSPSSTPTTHFSA 1873
Query: 889 GTDNKGNELPSAKLQDKQYISSVDKAP---FSEGSRNKTHKQGSTQSRLETSHTSKSSEP 945
+ G S + ++ +P + G ++ S+ +T H +SS
Sbjct: 1874 SSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTA 1933
Query: 946 SKSPDGIRNESRDSEISKRKTAE---QHSFGICKEKRARIEDDQSTR-----NISSSSPP 997
S G ESR S S T + + +E + ST + S++S
Sbjct: 1934 S----GRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGR 1989
Query: 998 EKEQPPREEPRVPPLKIQLSKIGPPFIIKSQPVSKPESRASTSTSVSGGRNTGARTLADI 1057
+E + I L ++ + + P S S T+ G +T L++
Sbjct: 1990 SEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPG-STTTPGLSEK 2048
Query: 1058 KARAQQARAQREAAAAAAVAAAASIVSGAMGSPGEGGKTRTLAHIKEQTKAKLFAKHQAR 1117
+ + A ++ + + S G T T A + T ++H
Sbjct: 2049 STTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTA-FPDSTTTPGLSRHSTT 2107
Query: 1118 AHLFQTSKETRLPPPLSSKEGPPNLEVS------STPETKMEGSTGVI------------ 1159
+H S +T L P ++ GP + ST GST +
Sbjct: 2108 SHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSS 2167
Query: 1160 -----------------IVNPNCR------SP-------SNKSAHLRETTTVLQ-----Q 1184
IV + R SP S+ S L+ +T Q
Sbjct: 2168 PGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPAST 2227
Query: 1185 SLNPSKLPETAT-----DLSVHSSDENIPVSHLSEKIVSSTSSENSSVPMLFNKN----- 1234
PS P TAT + H S + P +H SST+S +S +F+ +
Sbjct: 2228 HTTPSP-PSTATAPVEESTTYHRSPGSTPTTHFP---ASSTTSGHSEKSTIFHSSPDASG 2283
Query: 1235 SVPVSVCSTA----------ISGAIKEHPFVSSVDKSSVLMSVDSANTTISACNISMLKT 1284
+ P S ST IS E ++++ S+ + A+TT + S T
Sbjct: 2284 TTPSSAHSTTSGRGESTTSRISPGSTE---ITTLPGSTTTPGLSEASTTFYSSPRSPTTT 2340
Query: 1285 IQGTDTPCIAIIPKCIES-----TPISATTEGSSISSSMDDKQLLISSSSASNLVSTQYT 1339
+ + + + S + S + S+ + + ++ + SSS + +T +
Sbjct: 2341 LSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFP 2400
Query: 1340 SVPTPSIGNNLPN------LSTSSVLIPPMGINNRFPSEKIAIPGSEEQATVSMGTTVRA 1393
PT S+ P ST + L + E A PGS S T + A
Sbjct: 2401 RTPTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGS----PASTQTGLPA 2456
Query: 1394 ALSCSDSVAVTDSLVAHPTVAMFTGNMLTINSYDSPPKLSAESLDKNSGPRNRADNSGKP 1453
L+ +D + + P+ + TG L SP + + L S P + +S +
Sbjct: 2457 TLTTAD---LGEESTTFPSSSGSTGTTL------SPARSTTSGLVGESTPSRLSPSSTET 2507
Query: 1454 QQPPGGFAPAAINRSIPCKVIVDHSTTLTSSLSLTVSVESSEASLDLQGRPVRTEASVQP 1513
PG +++ S T S + T S SE S +P T +
Sbjct: 2508 TTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTT--- 2564
Query: 1514 VACPQVSVISRPEPVANEGIDHSSTFIAASAAKQDSKTLPATCTS 1558
+ P+ G+ ST +S D+ LPA+ T+
Sbjct: 2565 ---------AFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTT 2600
Score = 83.6 bits (205), Expect = 2e-15
Identities = 239/1163 (20%), Positives = 396/1163 (34%), Gaps = 170/1163 (14%)
Query: 545 PSTSSMTHVSDTEHKESETAVETSTPKIKTGSS---SLEGQFPNEGIA-IDMELQSDPEE 600
P S T S H + E++T +I GS+ +L G G++ S P
Sbjct: 3836 PDASGTTPSS--AHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRS 3893
Query: 601 QLSE-------NACISETSFSSESPEGACTSLPSPGGET------QSTSEESCTPASLET 647
+ + + E S +S S G+ S SP T +ST+ S +P S ET
Sbjct: 3894 PTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTET 3953
Query: 648 T-FCSEVSSTENTDKYNQRNSTDENFHASLMSEISPISTSPEISEASLMSNLPLTSEASP 706
T F +++ ++ +S + H +L +E S S E S A P S AS
Sbjct: 3954 TVFPRSTTTSVRREEPTTFHSRPASTHTTLFTEDSTTSGLTEESTA-----FP-GSPAST 4007
Query: 707 VSNLPLTSETSPMSDLPLTSETSSVSSMLLTSETTFVSSLPLPSETSPISNSSINERMAH 766
+ LP T T+ + + T +SS S T P S TS + S R++
Sbjct: 4008 QTGLPATLTTADLGEESTTFPSSSGS--------TGTKLSPARSTTSGLVGESTPSRLSP 4059
Query: 767 QQRKSPSVSEEPLSPQKDESSATAKPLGENLTSQQKNLSNTPEPIIMSSSSIAPEAFPSE 826
++ ++ P +P E S T + ++ T P +SS +
Sbjct: 4060 SSTETTTLPGSPTTPSLSEKSTT-------FYTSPRSPDATLSPATTTSSGV-------- 4104
Query: 827 DLHNKTLSQQTCKSHVDTEKPYPASIPELASTEMIK---VKNHSVLQRTEKKVLPSPLEL 883
S+++ SH + + P+ +T + +HS TE + P
Sbjct: 4105 -------SEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLSPGSTTA 4157
Query: 884 SVFSEGT---DNKGNELPSAKLQDKQYISSVDKAP----FSEGSRNKT-HKQGSTQSRLE 935
S + + + + + L D S + +A S GS + T ST + L+
Sbjct: 4158 SSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSTGLQ 4217
Query: 936 TSHTSKSSEPSKSPDGIRNESRDSEISKRKTAEQHSFGICKEKRARIEDDQSTRNISSSS 995
T+ S PS S D + + + + HS +T S S
Sbjct: 4218 EESTTFQSWPSSS-DTTPSPPSTTAVPVEVSTTYHS-RPSSTPTTHFSASSTTLGRSEES 4275
Query: 996 PPEKEQPPREEPRVPPLKIQLSKIGPPFIIKSQPVSKPESRASTSTSVSGGRNTGARTLA 1055
P + P + S ++ +P + P S ST T+ G T A L+
Sbjct: 4276 TTVHSSPGATGTALFPTRSATS------VLVGEPTTSPISSGSTETTALPGSTTTA-GLS 4328
Query: 1056 DIKARAQQARAQREAAAAAAVAAAASIVSGAMGSPGEGGKTRTLAHIKEQTKAKLFAKHQ 1115
+ + + + A ++ + + S G T A T + ++
Sbjct: 4329 EKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSMHTTAFPSSTTMPGV-SQES 4387
Query: 1116 ARAHLFQTSKETRLPP--PLSSKEGPPNLEVSSTP--------------------ETKME 1153
+H S +T L P +S GP + S+P T +
Sbjct: 4388 TASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVH 4447
Query: 1154 GSTGVIIVNPNCR-SPSNKSAHLRETTTVLQ--QSLNPSKLPETATDLSV------HSSD 1204
STG +P+ SP+ + E+TT S + + P T T V H S
Sbjct: 4448 SSTG----SPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSP 4503
Query: 1205 ENIPVSHLSEKIVSSTSSENSSVPMLFNKNSVPVSVCST------AISGAIKEHPFVSSV 1258
+ P +H S + SE S+ +S PV+ +T SG ++E S
Sbjct: 4504 SSTPTTHFSASSTTLGRSEEST-----TVHSSPVATATTPSPARSTTSGLVEESTTYHSS 4558
Query: 1259 DKSSVLMSVDSANTT------ISACNISMLKTIQGTDTPCIAII--PKCIESTPISATT- 1309
S+ M +NTT + + S TI + A++ P S+P S T
Sbjct: 4559 PGSTQTMHFPESNTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATT 4618
Query: 1310 ------------EGSSISSSMDD------------KQLLISSSSASNLV--STQYTSVPT 1343
E S+ S S D +L+ S+ S + S + T++P
Sbjct: 4619 HFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPG 4678
Query: 1344 PSIGNNLPNLSTSSVLIPPMGINNRFPSEKIAIPGSEEQATVSMGTTVRAALSCSDSVAV 1403
+ L ST+ P F + + SEE TV + V A + S + +
Sbjct: 4679 STTTPGLSEKSTTFHSSPSSTPTTHFSASSTTLGRSEESTTVH-SSPVATATTPSPARST 4737
Query: 1404 TDSLVAHPTVAMFT-GNMLTINSYDSPPKLSAESLDKNSGPRNRADNSGKPQQPPGGFAP 1462
T LV T + G+ T++ +S + S S P
Sbjct: 4738 TSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEE 4797
Query: 1463 AAINRSIPCKVIVDHSTTLTSSLSLTVSVESSEASLDLQG-RPV--------RTEASVQP 1513
S P + H +++ + +S +S D G P+ R S
Sbjct: 4798 PTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTF 4857
Query: 1514 VACPQVSVISRPEPVANEGIDHSSTFIAASAAKQDSKTLPATCTSLRELPLVPDKLNEPT 1573
P + G+ ST + +S+ D PA+ TS + P L
Sbjct: 4858 YISPGSMETTLASTATTPGLSAKSTILYSSSRSPDQTLSPASMTS-SSISGEPTSLYSQA 4916
Query: 1574 APSHNFAEQARGPAPFKSEADTT 1596
+H A A S+ TT
Sbjct: 4917 ESTHTTAFPASTTTSGLSQESTT 4939
Score = 82.8 bits (203), Expect = 3e-15
Identities = 236/1093 (21%), Positives = 370/1093 (33%), Gaps = 167/1093 (15%)
Query: 546 STSSMTHVSDTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMELQSDPEEQLSEN 605
+T ++ S T + S + ET T +T ++S+ G+ P S P +
Sbjct: 2375 TTPGLSEESTTVYSSSPGSTET-TVFPRTPTTSVRGEEPTT-------FHSRPAS--THT 2424
Query: 606 ACISETSFSSESPEGACTSLPSPGGETQSTSEESCTPASL---ETTFCSEVSSTENTDKY 662
+E S +S E + T+ P TQ+ + T A L TTF S ST T
Sbjct: 2425 TLFTEDSTTSGLTEES-TAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTT--- 2480
Query: 663 NQRNSTDENFHASLMSEISPISTSPEISEASLMSNLPLTSEASPVSNLPLTSETSPMSDL 722
S + + L+ E +P SP +E + + P T S S TS SP + L
Sbjct: 2481 ---LSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATL 2537
Query: 723 -PLTSETSSVSSMLLTSE--------TTFVSSLPLP--------SETSPIS--------- 756
P T+ +S VS TS T F S P S +SP S
Sbjct: 2538 SPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPAS 2597
Query: 757 -NSSINERMAHQQRKSPSVSEEPLSPQKDESSATAKPLGENLTSQQKNLSNTPEPIIMSS 815
+S + + SP ++ LSP S TA G+ T+ + +T + S
Sbjct: 2598 TTTSGPSQESTTSHSSPGSTDTALSP----GSTTALSFGQESTTFHSSPGSTHTTLFPDS 2653
Query: 816 SSIAPEAFPSEDLHNKTLSQQTCKSHVDTEKPYPASIPELASTEMIKVKNHSVLQRTEKK 875
++ + S +H+ T S +T T P ++ P L E + H T
Sbjct: 2654 TTSSGIVEASTRVHSSTGSPRT------TLSPASSTSPGLQG-ESTTFQTHPASTHT--- 2703
Query: 876 VLPSPLELSVFSEGTDNKGNELPSAKLQDKQYISSVDKAPFSEGSRNKTHKQGSTQSRLE 935
PSP PS + ++ ++P GS TH S+ +
Sbjct: 2704 -TPSP-----------------PSTATAPVEESTTYHRSP---GSTPTTHFPASSTT--- 2739
Query: 936 TSHTSKSSEPSKSPD--GIRNESRDSEISKRKTAEQHSFGICKEKRARIEDDQSTRNISS 993
+ H+ KS+ SPD G S S S R + + + +T +S
Sbjct: 2740 SGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSE 2799
Query: 994 SSPPEKEQPPREEPRVPPLKIQLSKIGPPFII-KSQPVSKPESRASTSTSVSGGRNTGAR 1052
+S P + P + +G +SQP S + + ST+ G
Sbjct: 2800 ASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTT 2859
Query: 1053 TLADIKARAQQARAQREAAAAAAVAAAASIVSGAMGSPGEGGKTRTLAHIKEQTKAKLFA 1112
+ + R + G + T T LF
Sbjct: 2860 VYSSSPGSTETTVFPRSTTTSV-----------------RGEEPTTFHSRPASTHTTLFT 2902
Query: 1113 KHQARAHLFQTSKETRLP-PPLSSKEGPP------NLEVSSTPETKMEGSTGVIIVNPNC 1165
+ + L T + T P P S++ G P +L ST GSTG +
Sbjct: 2903 EDSTTSGL--TEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARS 2960
Query: 1166 --------RSPSNKSAHLRETTTVLQQSLNPSKLPETATDL--SVHSSDENIPVSHLSEK 1215
+PS S ETTT+ PS L E +T S S D + + +
Sbjct: 2961 TTSGLVGESTPSRLSPSSTETTTLPGSPTTPS-LSEKSTTFYTSPRSPDATLSPATTTSS 3019
Query: 1216 IVSSTSSENSSVPMLFNKNSVPVSVCSTAISGAIKEHPFVSSVDKSSVLMSVDSANTTIS 1275
VS SS + S P + + P S ++ +S + P S + S ++ +TT S
Sbjct: 3020 GVSEESSTSHSQPGSTHTTAFPDSTTTSGLS----QEPTASHSSQGSTEATLSPGSTTAS 3075
Query: 1276 ACNISMLKTIQGT--DTPCIAIIPKCIESTPISATTEGSSISSSMDDKQLLISSSSAS-N 1332
+ T + DT + I S + A+T S + S+ SS+SA
Sbjct: 3076 SLG-QQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQ 3134
Query: 1333 LVSTQYTSVPTPSIGNNLP--------NLSTSSVLIPPMGINNRFPSEKIAIPGSEEQAT 1384
ST + S P+ S P +ST+ P F + + SEE T
Sbjct: 3135 EESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTT 3194
Query: 1385 V--SMGTTVRAALSCSDSVAV----------------TDSLVAHPTVAMFTGNMLTINSY 1426
V S G T A + +V T +L T A + T S
Sbjct: 3195 VHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSS 3254
Query: 1427 D-------SPPKLSAESLDKNSGPRNRADNSGKPQQPPGGFAPAAINRSIPCKVIVDHST 1479
SP ++ + + S + S PG +++ ST
Sbjct: 3255 PRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGST 3314
Query: 1480 TLTSSLSLTVSVESSEASLDLQGRPVRTEASVQPVACPQVSVISRPEPV-ANEGIDHSST 1538
T S T + S P TE ++ P ++ PV ++ G H++
Sbjct: 3315 DTTLSPGSTTASSLGPESTTFHSGPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTL 3374
Query: 1539 FIAASAAKQDSKT 1551
A S +Q T
Sbjct: 3375 SPAGSTTRQGEST 3387
Score = 78.6 bits (192), Expect = 7e-14
Identities = 227/1053 (21%), Positives = 358/1053 (33%), Gaps = 146/1053 (13%)
Query: 608 ISETSFSSESPEGACTSLPSPGGETQSTSEESCTPASLETTFCSEVSSTENTDKYNQRNS 667
+S+ S +S S G+ + SPG +T+ S P S TTF S T+ T
Sbjct: 332 VSQESTASHSIPGSTDTTLSPG----TTTPSSLGPES--TTFHSSPGYTKTT------RL 379
Query: 668 TDENFHASLMSEISPISTSPEISEASLMSNLPLTSEASPVS--NLPLTSETSPMSDLPLT 725
D + L+ +P+ +S +L + T E P + + P + +TSP
Sbjct: 380 PDNTTTSGLLEASTPVHSSTGSPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPAP----- 434
Query: 726 SETSSVSSMLLTSETTFVSSLPLPSETSPISNSSINERMAHQQRKSPSVSEEPLSPQKDE 785
S +S + TT+ SS PS T S+ + + H + +P V P++
Sbjct: 435 ---SGTTSAFVKLSTTYHSS---PSSTPTTHFSASSTTLGHSEESTP-VHSSPVATATTP 487
Query: 786 SSATAKPLG--ENLTSQQKNLSNTPEPIIMSSSSIAPEAFPSEDLHNKTLSQQTCKSHVD 843
A + G E T+ ++ +T SS+ + + S H T ++
Sbjct: 488 PPARSATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTT 547
Query: 844 TEKPYPASIPELASTEMIKVKNHSVLQ-RTEKKVL----PSPLELSVFSEGTDNKGNELP 898
+ + L STE ++ S + R+E+ P + +V G+ P
Sbjct: 548 AALAHTSYHSSLGSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGST------P 601
Query: 899 SAKLQDKQYISSVDKAPFSEGSRNKTHKQGSTQSR--LETSHTSKSSEPSKSPDGIRNES 956
S + D +P S GS T GST E S T SS S +
Sbjct: 602 SVLVGDST------PSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASM 655
Query: 957 RDSEISKRKTAEQHSFGICKEKRARIEDDQSTRNISSSSPPEKEQPPREEPRVPPLKIQL 1016
S +S+ T G + +S S P + + P
Sbjct: 656 TSSGVSEESTTSHSRPG--STHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTA 713
Query: 1017 SKIGPPFI-IKSQPVSKPESRASTSTSVSGGRNTGARTLADIKARAQQARAQREAAAAAA 1075
S +GP + S+P S + +T+ SG L + + + A
Sbjct: 714 SSLGPEYTTFHSRPGSTETTLLPDNTTASG--------LLEASMPVHSSTRSPHTTLSPA 765
Query: 1076 VAAAASIVSGAMGSPGEGGKTRTLAHIKEQTKAKLFAKHQARAHLFQTSKETRLPPPLSS 1135
+ S S TR T F + +H +S T +S+
Sbjct: 766 GSTTRQGESTTFHSWPSSKDTRPAP----PTTTSAFVEPSTTSHGSPSSIPTT---HISA 818
Query: 1136 KEGPPNLEVSSTPETKMEGSTGVIIV----NPNCRSPSNKSAHLRETTTVLQQSLNPSKL 1191
+ L ST GST + + R + ++H T T+ S L
Sbjct: 819 RSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSAL 878
Query: 1192 PETATDLSVHSSDENIPVSHLSEKIVSSTSSENSSVPMLFNKNSVPVSVCSTAISGAIKE 1251
E T S HSS + +H + +S SE S+ S S +G I
Sbjct: 879 VEEPT--SYHSSPGSTATTHFPDSSTTSGRSEESTA-----------SHSSQDATGTI-- 923
Query: 1252 HPFVSSVDKSSVLMSVDSANTTISACNISMLKTIQGTDTPCIAIIPKCIESTPISATTE- 1310
+ + +SVL+ +S + IS+ ++ T TP ++ S+P S T
Sbjct: 924 --VLPARSTTSVLLG-ESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTL 980
Query: 1311 --GSSISSSMDDKQLLISSSSASNLVSTQYTSVPTPSIGNNLPNLSTSSVLIPPMGINNR 1368
S+ SS + ++ S++S S ST T+ P + L ST+S P
Sbjct: 981 SPASTTSSGVSEE----STTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTL 1036
Query: 1369 FPSEKIAIPGSEEQATV--SMGTTVRA-------ALSCS-------------------DS 1400
P+ S+E T S G+T A ALS DS
Sbjct: 1037 LPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDS 1096
Query: 1401 VAVTDSLVAHPTVAMFTGNMLTINSYDSP--PKLSAESLDKNSGPRNRADNSGKPQQPPG 1458
+ + A V TG+ T S S P L ES + P A P P
Sbjct: 1097 TTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHP---ASTHTTPSPPST 1153
Query: 1459 GFAPAAINR-------SIPCKVIVDHSTTLTSSLSLTVSVESSEAS--------LDLQGR 1503
AP + S P STT S T+ S +AS GR
Sbjct: 1154 ATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGR 1213
Query: 1504 PVRTEASVQPVACPQVSVISRPEPVANEGIDHSSTFIAASAAKQDSKTLPATCTSLRELP 1563
T + + P + + + P G+ +ST +S + PA+ TSL
Sbjct: 1214 GESTTSRISPGS---TEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGE 1270
Query: 1564 LVPDKLNEPTAPSHNFAEQARGPAPFKSEADTT 1596
++P +H+ A P SE TT
Sbjct: 1271 ESTTSRSQP-GSTHSTVSPASTTTPGLSEESTT 1302
Score = 76.3 bits (186), Expect = 3e-13
Identities = 268/1336 (20%), Positives = 438/1336 (32%), Gaps = 195/1336 (14%)
Query: 395 SAQTALAEQQPKSMKSPASPEPGFCATL--CPMVEIPPKDIMAELESEDILIPEESVIQE 452
S + L E+ SPAS + G ATL + E + + L P S
Sbjct: 2905 STTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSG 2964
Query: 453 EIAEEVETSICECQDE-----NHKTIPEFSEEAESLTNSHEEPQ--IAP--------PED 497
+ E + + E T P SE++ + S P ++P E+
Sbjct: 2965 LVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEE 3024
Query: 498 NLESCVMMNDVLETLPHIEVKIEGKSESPQEEMTVVIDQLEVCDSLIPSTSSMTHVSDTE 557
+ S T G S+ P + + SS+ S T
Sbjct: 3025 SSTSHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTEATLSPGSTTASSLGQQSTTF 3084
Query: 558 HKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMELQSDPEEQLSENACISETSFSSES 617
H T P S +E P + P S +A + E S + +S
Sbjct: 3085 HSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPAS--STSAGLQEESTTFQS 3142
Query: 618 PEGACTSLPSPGGETQSTSEESCT----PASLETTFCSEVSST-----ENTDKYNQRNST 668
+ + PSP G T + E S T P+S TT S S+T E+T ++ +T
Sbjct: 3143 WPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGAT 3202
Query: 669 DENFHASLMSE---ISPISTSPEISEASLMSNLPLTSEASPVSNLPLTSETSPMSDLPLT 725
+ + + +TSP S ++ + LP ++ + +S T +SP S
Sbjct: 3203 GTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTL 3262
Query: 726 SETSSVSSMLLTSETTFVSSLPLPSETSPISNSSINERMAHQ---QRKSPSVSEEPLSPQ 782
S S+ SS ++ E+T S P + T+ S+ ++ + SP ++ LSP
Sbjct: 3263 SPASTTSSG-VSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSP- 3320
Query: 783 KDESSATAKPLGENLTSQQKNLSNTPEPIIMSSSSIAPEAFPSEDLHNKTLSQQTCKSHV 842
S TA LG T+ +T ++ +++ + S +H+ T S T S
Sbjct: 3321 ---GSTTASSLGPESTTFHSGPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPA 3377
Query: 843 DT-----EKPYPASIPELASTEMIKVKNHS--VLQRTEKKVLPSPLELSVFSEGTDNKGN 895
+ E S P T S V T PS + FS + G
Sbjct: 3378 GSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGR 3437
Query: 896 ELPSAKLQDKQYISSVDKAP--------------------------FSEGSRNKTHKQGS 929
S + ++ +P F E + S
Sbjct: 3438 SEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEES 3497
Query: 930 TQSRLETSHTSKSSEPSKS---------------------PDGIRNESRDSEISKRKTAE 968
T S T+HT S+ + S PD R E + +++
Sbjct: 3498 TTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQ 3557
Query: 969 QHSFGICKEKRAR---IEDDQSTRNISSSSP--------------PEKEQPPREEPRVPP 1011
+ I R+ + + +T ISS S EK PR P
Sbjct: 3558 DATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPA 3617
Query: 1012 LKIQLSKIGPPFIIKSQPVSKPESRASTSTSVSGGRNTGA---RTLADIKARAQQARAQR 1068
+ P S VS+ ++TS S G +T A T +R
Sbjct: 3618 TTLS------PASTTSSGVSE---ESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSS 3668
Query: 1069 EAAAAAAVAAAASIVSG----AMGSPGEGGKTRTLAHIKEQTKAKLFAKHQARAHLFQTS 1124
+ + A++ SG + S G T T A T A F + H S
Sbjct: 3669 PGSTDTTLLPASTTTSGSSQESTTSHSSSGSTDT-ALSPGSTTALSFGQESTTFHSSPGS 3727
Query: 1125 KETRLPPPLSSKEGPPNLEVSSTPETKMEGSTGVIIVNPNCRSPSNKSAHLRETTTVLQQ 1184
T L P ++ G + +ST GS + + SP + T
Sbjct: 3728 THTTLFPDSTTSSG---IVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPAST 3784
Query: 1185 SLNPSKLPETAT-----DLSVHSSDENIPVSHLSEKIVSSTSSENSSVPMLFNKN----- 1234
PS P TAT + H S + P +H SST+S +S +F+ +
Sbjct: 3785 HTTPSP-PSTATAPVEESTTYHRSPGSTPTTHFP---ASSTTSGHSEKSTIFHSSPDASG 3840
Query: 1235 SVPVSVCSTA----------ISGAIKEHPFVSSVDKSSVLMSVDSANTTISACNISMLKT 1284
+ P S ST IS E ++++ S+ + A+TT + S T
Sbjct: 3841 TTPSSAHSTTSGRGESTTSRISPGSTE---ITTLPGSTTTPGLSEASTTFYSSPRSPTTT 3897
Query: 1285 IQGTDTPCIAIIPKCIES-----TPISATTEGSSISSSMDDKQLLISSSSASNLVSTQYT 1339
+ + + + S + S + S+ + + ++ + SSS + +T +
Sbjct: 3898 LSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFP 3957
Query: 1340 SVPTPSIGNNLPN------LSTSSVLIPPMGINNRFPSEKIAIPGSEEQATVSMGTTVRA 1393
T S+ P ST + L + E A PGS S T + A
Sbjct: 3958 RSTTTSVRREEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGS----PASTQTGLPA 4013
Query: 1394 ALSCSDSVAVTDSLVAHPTVAMFTGNMLTINSYDSPPKLSAESLDKNSGPRNRADNSGKP 1453
L+ +D + + P+ + TG L SP + + L S P + +S +
Sbjct: 4014 TLTTAD---LGEESTTFPSSSGSTGTKL------SPARSTTSGLVGESTPSRLSPSSTET 4064
Query: 1454 QQPPGGFAPAAINRSIPCKVIVDHSTTLTSSLSLTVSVESSEASLDLQGRPVRTEASVQP 1513
PG +++ S T S + T S SE S +P T + P
Sbjct: 4065 TTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFP 4124
Query: 1514 VACPQVSVISRPEPVANEGIDHSSTFIAASAAKQDSKTLPATCTSLRELP------LVPD 1567
+ + P ST S + +L T+ P L+PD
Sbjct: 4125 DSTTTSGLSQEP---TTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPD 4181
Query: 1568 K-----LNEPTAPSHN 1578
L E + P+H+
Sbjct: 4182 DTITSGLVEASTPTHS 4197
Score = 75.1 bits (183), Expect = 7e-13
Identities = 254/1278 (19%), Positives = 416/1278 (32%), Gaps = 195/1278 (15%)
Query: 546 STSSMTHVSDTEHKESETAVETSTPKIKTGSSSLEGQ--FPNEGIAIDMELQSDPEEQLS 603
+TS +T S T S + +T P T + E FP+ + L + +
Sbjct: 2432 TTSGLTEES-TAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSP---ARST 2487
Query: 604 ENACISETSFSSESPEGACTSLPSPGGETQSTSEESCT-------------PASLETTFC 650
+ + E++ S SP T+ T S SE+S T PA+ ++
Sbjct: 2488 TSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGV 2547
Query: 651 SEVSSTENTDKYNQRNST--DENFHASLMSEISPISTSPEISEASLMSNLPLTSEASPVS 708
SE SST ++ + + D L + +SP ++ +L LP ++ S S
Sbjct: 2548 SEESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTL---LPASTTTSGPS 2604
Query: 709 NLPLTSETSPMSDLPLTSETSSVSSMLLTSETTFVSSLPLPSETSPISNSSINERMAHQQ 768
TS +SP S S S+ + TTF SS P + T+ +S+ + +
Sbjct: 2605 QESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSS-PGSTHTTLFPDSTTSSGIVEAS 2663
Query: 769 RKSPSVSEEPLSPQKDESSATAKPLGENLTSQQKNLSN--TPEPIIMSSSSI-------- 818
+ S + P + SS + GE+ T Q S TP P +++ +
Sbjct: 2664 TRVHSSTGSPRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPSTATAPVEESTTYHR 2723
Query: 819 APEAFPSEDLH-NKTLSQQTCKSHVDTEKPYPASIPELASTEMIKVKNHSVLQRTEKKVL 877
+P + P+ + T S + KS + P + ++ + S T ++
Sbjct: 2724 SPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGES----TTSRIS 2779
Query: 878 PSPLELSVFSEGTDNKGNELPSAKLQDKQYISSVDKAPFS-------EGSRNKTHKQGST 930
P E++ T G S + +P S E S + GST
Sbjct: 2780 PGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGST 2839
Query: 931 QSRL-----------ETSHTSKSSEPSKSPDGIRNESRDSEISKRKTAEQHSFGICKEKR 979
S + E S T SS P + + S + + + HS
Sbjct: 2840 HSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRGEEPTTFHSRP-ASTHT 2898
Query: 980 ARIEDDQSTRNISSSSPPEKEQPPREEPRVPPLKIQLSKIGPPFIIKSQPVSKPESRAST 1039
+D +T ++ S P + +P + + +G + + P S ST
Sbjct: 2899 TLFTEDSTTSGLTEESTAFPGSPASTQTGLPAT-LTTADLG------EESTTFPSSSGST 2951
Query: 1040 STSVSGGRNT------------------------GARTLADIKARAQQ---ARAQREAAA 1072
T++S R+T G+ T + ++ + +A
Sbjct: 2952 GTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATL 3011
Query: 1073 AAAVAAAASIVSGAMGSPGEGGKTRTLAHIKEQTKAKLFAKHQARAHLFQTSKETRLPPP 1132
+ A ++ + + S + G T T A T + L ++ +H Q S E L P
Sbjct: 3012 SPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGL-SQEPTASHSSQGSTEATLSPG 3070
Query: 1133 LSSKEG-----------PPNLEVSSTPE-----------TKMEGSTGVIIVNPNCRSPSN 1170
++ P + E + P+ T STG + + S+
Sbjct: 3071 STTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSL--HTTLTPASS 3128
Query: 1171 KSAHLRETTTVLQQ-----SLNPSKLPETATDLSV----HSSDENIPVSHLSEKIVSSTS 1221
SA L+E +T Q PS TA + V HS + P +H S +
Sbjct: 3129 TSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGR 3188
Query: 1222 SENS----SVPMLFNKNSVPVSVCSTAISGAIKEHPFVSSVDKSSVLMSVDSANTTISAC 1277
SE S S P P ++ + G P S + S + +TT +
Sbjct: 3189 SEESTTVHSSPGATGTALFPTRSATSVLVG----EPTTSPISSGSTETTALPGSTTTAGL 3244
Query: 1278 NISMLKTIQGTDTPCIAIIPKCIESTPISATTEGSSISSSMDDKQLLISSSSASNLVSTQ 1337
+ +P + P A+T S +S S++S S ST
Sbjct: 3245 SEKSTTFYSSPRSPDTTLSP---------ASTTSSGVSEE--------STTSHSRPGSTH 3287
Query: 1338 YTSVPTPSIGNNLPNLSTSSVLIPPMGINNRFPSEKIAIPGSEEQATVSMGTTVRAALSC 1397
T+ P + + ST+S P P A E T G
Sbjct: 3288 TTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSGPGSTETTLL 3347
Query: 1398 SDSVAVTDSLVAHPTVAMFTGNMLTINSYDSPPKLSAESLDKNSGPRNRADNSGKPQQPP 1457
D+ + L A V TG+ T S ES S P N D + P
Sbjct: 3348 PDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWP-NSKDTTPAPPTTT 3406
Query: 1458 GGFAPAAINRSIPCKVIVDHSTTLTSSLSLTVSVESSEASLDLQGRPVRTEASVQPVACP 1517
F V+ STT S S T + S +S L T PVA
Sbjct: 3407 SAF--------------VELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVA-- 3450
Query: 1518 QVSVISRPEPVANEGIDHSSTFIAASAAKQDSKTLPATCTSLRELPLVPDKLNEPTAPSH 1577
+ P G+ ST +S + P + T+ E + SH
Sbjct: 3451 -TATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGR--------GEESTTSH 3501
Query: 1578 NFAEQARGPAPFKSEADTTCSNQYNPSNRICWNDDGMRSTGQPLVTHSGSSKQKEYLEQS 1637
+ AP + A Y+ S G TH S +
Sbjct: 3502 SSTTHTISSAPSTTSALVEEPTSYHSS------------PGSTATTHFPDSSTTSGRSEE 3549
Query: 1638 CPKAIKTEHANYLNVSELHPRNLVTNVALPVKSELHEADKGFRMDTEDFPGPELPPPAAE 1697
+ ++ A V P T+V L +S G M+T PG P +E
Sbjct: 3550 STASHSSQDATGTIVL---PARSTTSVLLG-ESTTSPISSG-SMETTALPGSTTTPGLSE 3604
Query: 1698 GASSVQQTQNMKASTSSP 1715
+++ + A+T SP
Sbjct: 3605 KSTTFHSSPRSPATTLSP 3622
Score = 73.9 bits (180), Expect = 2e-12
Identities = 221/1073 (20%), Positives = 370/1073 (34%), Gaps = 178/1073 (16%)
Query: 546 STSSMTHVSDTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMELQSDPEEQLSEN 605
S SS TH + + VE T + S+ FP+ S
Sbjct: 1943 SHSSTTHTISSPPSTTSALVEEPTSYHSSPGSTATTHFPDS----------------STT 1986
Query: 606 ACISETSFSSESPEGACTSLPSPGGETQST--SEESCTPASLETTFCSEVSSTENTDKYN 663
+ SE S +S S + A ++ P T S E + +P S + + + + T +
Sbjct: 1987 SGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLS 2046
Query: 664 QRNSTDENFHASLMSEISPISTSPEISEASLMSNLPLTSEASPVSN----LPLTSETSPM 719
++++T FH+S S + +S P + +S +S TS + P S P ++ T +
Sbjct: 2047 EKSTT---FHSSPRSPATTLS--PASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGL 2101
Query: 720 SDLPLTSETS--SVSSMLLTSETTFVSSLPLPSETSPISNSSINERMAHQQRKSPSVSEE 777
S TS +S S + LL + TT PS+ S S+SS P ++
Sbjct: 2102 SRHSTTSHSSPGSTDTTLLPASTTTSG----PSQESTTSHSS------------PGSTDT 2145
Query: 778 PLSPQKDESSATAKPLGENLTSQQKNLSNTPEPIIMSSSSIAPEAFPSEDLHNKTLSQQT 837
LSP S TA G+ T+ + +T + S++ + S +H+ T S +T
Sbjct: 2146 ALSP----GSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRT 2201
Query: 838 CKSHVDTEKPYPASIPELASTEMIKVKNHSVLQRTEKKVLPSPLELSVFSEGTDNKGNEL 897
T P ++ P L E + H T PSP
Sbjct: 2202 ------TLSPASSTSPGLQG-ESTAFQTHPASTHTT----PSP----------------- 2233
Query: 898 PSAKLQDKQYISSVDKAPFSEGSRNKTHKQGSTQSRLETSHTSKSSEPSKSPD--GIRNE 955
PS + ++ ++P GS TH S+ + + H+ KS+ SPD G
Sbjct: 2234 PSTATAPVEESTTYHRSP---GSTPTTHFPASSTT---SGHSEKSTIFHSSPDASGTTPS 2287
Query: 956 SRDSEISKRKTAEQHSFGICKEKRARIEDDQSTRNISSSSPPEKEQPPREEPRVPPLKIQ 1015
S S S R + + + +T +S +S P + P +
Sbjct: 2288 SAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMT 2347
Query: 1016 LSKIGPPFII-KSQPVSKPESRASTSTSVSGGRNTGARTLADIKARAQQARAQREAAAAA 1074
+G +SQP S + + ST+ G + + R +
Sbjct: 2348 SLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRTPTTSV 2407
Query: 1075 AVAAAASIVSGAMGSPGEGGKTRTLAHIKEQTKAKLFAKHQARAHLFQTSKETRLP-PPL 1133
G + T T LF + + L T + T P P
Sbjct: 2408 -----------------RGEEPTTFHSRPASTHTTLFTEDSTTSGL--TEESTAFPGSPA 2448
Query: 1134 SSKEGPP------NLEVSSTPETKMEGSTGVIIVNPNCRSPSNKSAHLRETTTVLQQSLN 1187
S++ G P +L ST GSTG + SP+ R TT+ L
Sbjct: 2449 STQTGLPATLTTADLGEESTTFPSSSGSTGTTL------SPA------RSTTSGLVGEST 2496
Query: 1188 PSKLPETATDLSVHSSDENIPVSHLSEKIVSSTSSENSSVPMLFNKNSVPVSVCSTAISG 1247
PS+L ++T+ + P LSEK + +S S +S +T SG
Sbjct: 2497 PSRLSPSSTETTTLPGSPTTP--SLSEKSTTFYTSPRSP--------DATLSPATTTSSG 2546
Query: 1248 AIKEHPFVSSVDKSSVLMSVDSANTT--ISACNISMLKTIQGTDTPCIAIIPKCIESTPI 1305
+E S S+ + + TT +S + + + TDT ++P ++
Sbjct: 2547 VSEESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDT---TLLPASTTTSGP 2603
Query: 1306 SATTEGSSISSSMDDKQLLISSSSASNL--VSTQYTSVPTPSIGNNLPNLSTSSVLIPPM 1363
S + S S D L S++A + ST + S P + P+ +TSS ++
Sbjct: 2604 SQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEA- 2662
Query: 1364 GINNRFPSEKIAIPGSEEQATVSMGTTVRAALSCSDSVAVTDSLVAHPTVAMFTGNMLTI 1423
S ++ + T+S ++ L + T H T
Sbjct: 2663 -------STRVHSSTGSPRTTLSPASSTSPGLQGESTTFQTHPASTHTT----------- 2704
Query: 1424 NSYDSPPKLSAESLDKNSGPRNRADNSGKPQQPPGGFAPAAINRSIPCKVIVDHSTTLTS 1483
SPP + +++++ ++ P +S D S T S
Sbjct: 2705 ---PSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPS 2761
Query: 1484 SLSLTVSVESSEASLDLQGRPVRTEASVQPVACPQVSVISRPEPVANEGIDHSSTFIAAS 1543
S T S GR T + + P + + + P G+ +ST +S
Sbjct: 2762 SAHSTTS-----------GRGESTTSRISPGS---TEITTLPGSTTTPGLSEASTTFYSS 2807
Query: 1544 AAKQDSKTLPATCTSLRELPLVPDKLNEPTAPSHNFAEQARGPAPFKSEADTT 1596
+ PA+ TSL ++P +H+ A P SE TT
Sbjct: 2808 PRSPTTTLSPASMTSLGVGEESTTSRSQP-GSTHSTVSPASTTTPGLSEESTT 2859
Score = 73.6 bits (179), Expect = 2e-12
Identities = 252/1260 (20%), Positives = 417/1260 (33%), Gaps = 185/1260 (14%)
Query: 546 STSSMTHVSDTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAI-DMELQSDPEEQLSE 604
ST+S T S+ A T ++ +S L G+ I+ ME + P +
Sbjct: 901 STTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTP 960
Query: 605 NACISETSFSSESPEGACTSLPSPGGETQSTSEESCT----PASLETTFCSEVSSTENTD 660
T+F S SP T+L + SEES T P S TT + ++T
Sbjct: 961 GLSERSTTFHS-SPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLS 1019
Query: 661 KYNQRNSTDENFHASLMSEISPISTSPEISEASLMSNLPLTSEA-SPVSNLPLT--SETS 717
+++ + + + + S ++ P + S+ T A SP S L+ E++
Sbjct: 1020 RHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQEST 1079
Query: 718 PMSDLPLTSET-----SSVSSMLLTSETTFVSSLPLPSET-SPISNSSINERMAHQQRKS 771
P ++ T S+ SS ++ + T SS P T SP S++S Q +S
Sbjct: 1080 TFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPG-----LQGES 1134
Query: 772 PSVSEEPLSPQKDESS-ATAKPLGENLTSQQKNLSNTPEPIIMSSSSIAPEAFPSEDLHN 830
+ P S S +TA E T+ ++ +TP +SS+ + + S H
Sbjct: 1135 TAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFH- 1193
Query: 831 KTLSQQTCKSHVDTEKPYPASIPELASTEMIKVKNHSVLQRTEKKVLPSPLELSVFSEGT 890
S D P+S S + T ++ P E++ T
Sbjct: 1194 ---------SSPDASGTTPSSAHSTTSGRG---------ESTTSRISPGSTEITTLPGST 1235
Query: 891 DNKGNELPSAKLQDKQYISSVDKAPFSEGSRNKTHKQGSTQSRLETSHTSKSSEPSKSPD 950
G S + +P S S + +++S+ ++H++ S + +P
Sbjct: 1236 TTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTP- 1294
Query: 951 GIRNESRDSEISKRKTAEQHSF------GICKEKRARIEDDQSTRNISSSSPPEKEQPPR 1004
G+ ES S R + E F + E+ ++ + + +
Sbjct: 1295 GLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLT 1354
Query: 1005 EEPRVPPLKIQLSKIGPPFIIKSQPVSK-----PESRASTSTSVSGGRNT---------- 1049
EE P ++ G P + + + + P S ST T +S R+T
Sbjct: 1355 EESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTP 1414
Query: 1050 --------------GARTLADIKARAQQ---ARAQREAAAAAAVAAAASIVSGAMGSPGE 1092
G+ T + ++ + +A + A ++ + + S +
Sbjct: 1415 SRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQ 1474
Query: 1093 GGKTRTLAHIKEQTKAKLFAKHQARAHLFQTSKETRLPPPLSSKEG-----------PPN 1141
G T T A T + L ++ +H Q S E L P ++ P +
Sbjct: 1475 PGSTHTTAFPDSTTTSDL-SQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGD 1533
Query: 1142 LEVSSTPE-----------TKMEGSTGVIIVNPNCRSPSNKSAHLRETTTVLQQ-----S 1185
E + P+ T STG + + S+ SA L+E +T Q
Sbjct: 1534 TETTLLPDDTITSGLVEASTPTHSSTGSL--HTTLTPASSTSAGLQEESTTFQSWPSSSD 1591
Query: 1186 LNPSKLPETATDLSV----HSSDENIPVSHLSEKIVSSTSSENS----SVPMLFNKNSVP 1237
PS TA + V HS + P +H S + SE S S P P
Sbjct: 1592 TTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFP 1651
Query: 1238 VSVCSTAISGAIKEHPFVSSVDKSSVLMSVDSANTTISACNISMLKTIQGTDTPCIAIIP 1297
++ + G P S + S + +TT + + +P + P
Sbjct: 1652 TRSATSVLVG----EPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSP 1707
Query: 1298 KCIESTPISATTEGSSISSSMDDKQLLISSSSASNLVSTQYTSVPTPSIGNNLPNLSTSS 1357
A+T S +S S++S S ST T+ P + + ST+S
Sbjct: 1708 ---------ASTTSSGVSEE--------STTSHSRPGSTHTTAFPGSTTMPGVSQESTAS 1750
Query: 1358 VLIPPMGINNRFPSEKIAIPGSEEQATV--SMGTTVRAALSCSDSVAVTDSLVAHPTVAM 1415
P P A E T S G+T L D+ + L A V
Sbjct: 1751 HSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLP--DNTTASGLLEASTPVHS 1808
Query: 1416 FTGNMLTINSYDSPPKLSAESLDKNSGPRNRADNSGKPQQPPGGFAPAAINRSIPCKVIV 1475
TG+ T S ES S P ++ D P F V
Sbjct: 1809 STGSPHTTLSPAGSTTRQGESTTFQSWPSSK-DTMPAPPTTTSAF--------------V 1853
Query: 1476 DHSTTLTSSLSLTVSVESSEASLDLQGRPVRTEASVQPVACPQVSVISRPEPVANEGIDH 1535
+ STT S S T + S +S L T PVA + P G+
Sbjct: 1854 ELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVA---TATTPSPARSTTSGLVE 1910
Query: 1536 SSTFIAASAAKQDSKTLPATCTSLRELPLVPDKLNEPTAPSHNFAEQARGPAPFKSEADT 1595
ST +S + P + T+ +E + SH+ P + A
Sbjct: 1911 ESTAYHSSPGSTQTMHFPESSTASGR--------SEESRTSHSSTTHTISSPPSTTSALV 1962
Query: 1596 TCSNQYNPSNRICWNDDGMRSTGQPLVTHSGSSKQKEYLEQSCPKAIKTEHANYLNVSEL 1655
Y+ S G TH S + + ++ A V
Sbjct: 1963 EEPTSYHSS------------PGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVL-- 2008
Query: 1656 HPRNLVTNVALPVKSELHEADKGFRMDTEDFPGPELPPPAAEGASSVQQTQNMKASTSSP 1715
P T+V L +S G M+T PG P +E +++ + A+T SP
Sbjct: 2009 -PARSTTSVLLG-ESTTSPISSG-SMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSP 2065
Score = 67.8 bits (164), Expect = 1e-10
Identities = 224/1102 (20%), Positives = 371/1102 (33%), Gaps = 160/1102 (14%)
Query: 546 STSSMTHVSDTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMELQSDPEEQLSEN 605
+T + S T H T +P T S +E + PE +
Sbjct: 3433 TTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSG 3492
Query: 606 ACISETSFSSESPEGACTSLPSPGGETQSTSEESCTPASLETTFCSEVSST-----ENTD 660
T+ S + ++ + + + +P S TT + S+T E+T
Sbjct: 3493 RGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTA 3552
Query: 661 KYNQRNSTDENF--HASLMSEISPISTSPEISEASLMSN-LPLTSEASPVSNLPLTSETS 717
++ +++T S S + ST+ IS S+ + LP ++ +S T +S
Sbjct: 3553 SHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSS 3612
Query: 718 PMSDLPLTSETSSVSSMLLTSETTFVSSLPLPSETSPISNSSIN---ERMAHQQRKSPSV 774
P S S S+ SS ++ E+T S P + T+ +S+ R + SP
Sbjct: 3613 PRSPATTLSPASTTSSG-VSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGS 3671
Query: 775 SEEPLSPQK------------------------DESSATAKPLGENLTSQQKNLSNTPEP 810
++ L P S TA G+ T+ + +T
Sbjct: 3672 TDTTLLPASTTTSGSSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTT 3731
Query: 811 IIMSSSSIAPEAFPSEDLHNKTLSQQTCKSHVDTEKPYPASIPELASTEMIKVKNHSVLQ 870
+ S++ + S +H+ T S +T T P ++ P L E + H
Sbjct: 3732 LFPDSTTSSGIVEASTRVHSSTGSPRT------TLSPASSTSPGLQG-ESTAFQTHPAST 3784
Query: 871 RTEKKVLPSPLELSVFSEGTDNKGNELPSAKLQDKQYISSVDKAPFSEGSRNKTHKQGST 930
T PSP PS + ++ ++P GS TH S+
Sbjct: 3785 HT----TPSP-----------------PSTATAPVEESTTYHRSP---GSTPTTHFPASS 3820
Query: 931 QSRLETSHTSKSSEPSKSPD--GIRNESRDSEISKRKTAEQHSFGICKEKRARIEDDQST 988
+ + H+ KS+ SPD G S S S R + + + +T
Sbjct: 3821 TT---SGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTT 3877
Query: 989 RNISSSSPPEKEQPPREEPRVPPLKIQLSKIGPPFII-KSQPVSKPESRASTSTSVSGGR 1047
+S +S P + P + +G +SQP S + + ST+ G
Sbjct: 3878 PGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPG-- 3935
Query: 1048 NTGARTLADIKARAQQARAQREAAAAAAVAAAASIVSGAMGSPGEGGKTRTLAHIKEQTK 1107
+ + + + V ++ S P T T
Sbjct: 3936 ---------LSEESTTVYSSSPGSTETTVFPRSTTTSVRREEP------TTFHSRPASTH 3980
Query: 1108 AKLFAKHQARAHLFQTSKETRLP-PPLSSKEGPP------NLEVSSTPETKMEGSTGVII 1160
LF + + L T + T P P S++ G P +L ST GSTG +
Sbjct: 3981 TTLFTEDSTTSGL--TEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKL 4038
Query: 1161 VNPNC--------RSPSNKSAHLRETTTVLQQSLNPSKLPETATDL--SVHSSDENIPVS 1210
+PS S ETTT+ PS L E +T S S D + +
Sbjct: 4039 SPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPS-LSEKSTTFYTSPRSPDATLSPA 4097
Query: 1211 HLSEKIVSSTSSENSSVPMLFNKNSVPVSVCSTAISGAIKEHPFVSSVDKSSVLMSVDSA 1270
+ VS SS + S P + + P S ++ +S + P S + S ++
Sbjct: 4098 TTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLS----QEPTTSHSSQGSTEATLSPG 4153
Query: 1271 NTTISACNISMLKTIQGT--DTPCIAIIPKCIESTPISATTEGSSISSSMDDKQLLISSS 1328
+TT S+ T + DT + I S + A+T S + S+ L +SS
Sbjct: 4154 STTASSLG-QQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSL-HTTLTPASS 4211
Query: 1329 SASNLVSTQYTSVPTPSIGNNLPN----------LSTSSVLIPPMGINNRFPSEKIAIPG 1378
+++ L T PS + P+ +ST+ P F + +
Sbjct: 4212 TSTGLQEESTTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASSTTLGR 4271
Query: 1379 SEEQATV--SMGTTVRAALSCSDSVAVTDSLVAHPTVAMFTG---NMLTINSYDSPPKLS 1433
SEE TV S G T A + +V LV PT + + + + LS
Sbjct: 4272 SEESTTVHSSPGATGTALFPTRSATSV---LVGEPTTSPISSGSTETTALPGSTTTAGLS 4328
Query: 1434 AESLDKNSGPRNR--------------ADNSGKPQQPPGGFAPAAINRSIPCKVIVDHST 1479
+S S PR+ ++ S PG A S + ST
Sbjct: 4329 EKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSMHTTAFPSSTTMPGVSQEST 4388
Query: 1480 TLTS---SLSLTVSVESSEA------SLDLQGRPVRTEASVQPVACPQVSVISRPEPV-A 1529
S S T+S S+ A S P TE ++ P ++ PV +
Sbjct: 4389 ASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHS 4448
Query: 1530 NEGIDHSSTFIAASAAKQDSKT 1551
+ G H++ A S +Q T
Sbjct: 4449 STGSPHTTLSPAGSTTRQGEST 4470
Score = 67.4 bits (163), Expect = 2e-10
Identities = 268/1354 (19%), Positives = 453/1354 (33%), Gaps = 212/1354 (15%)
Query: 383 SSSSCGTSGLPVSAQTA-LAEQQPKSMKSPASPEPGFCATLCPMVEIPPKDIMAELE--- 438
+S+S T+ LP S TA L+E+ SP SP+ + K +
Sbjct: 258 TSASMETTALPGSTTTAGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGP 317
Query: 439 SEDILIPE---------ESVIQEEIAEEVETSICECQDENHKTIPEFS--EEAESLTNSH 487
+ I P+ ES I +T++ PE + + T +
Sbjct: 318 THTIAFPDSTTMPGVSQESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTT 377
Query: 488 EEPQIAPPEDNLESCVMMNDVLETLPHIEVKIEGKSESPQEEMTVVIDQLEVCDSLIPS- 546
P LE+ ++ + PH + + E T S PS
Sbjct: 378 RLPDNTTTSGLLEASTPVHSSTGS-PHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPAPSG 436
Query: 547 -TSSMTHVSDTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMELQSDPEEQLSEN 605
TS+ +S T H + T T E P + + P + + +
Sbjct: 437 TTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPVHSSPV-ATATTPPPARSATS 495
Query: 606 ACISETSFSSESPEGACTSLPSPGGETQSTSEESC----------------TPASLETTF 649
+ E++ SP T T SEES T A T++
Sbjct: 496 GHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSY 555
Query: 650 CSEVSSTENT-----DKYNQRNSTDENFHAS---LMSEISPISTSPEI----SEASLMSN 697
S + STE T + R+ + H+S + + + P ++P + S S +S+
Sbjct: 556 HSSLGSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISS 615
Query: 698 LPLTSEASPVSNLP--LTSETSPMSDLPLTSET----SSVSSMLLTSETTFVSSLPLPSE 751
+ + A P S L+ +++ P + +T +S++S ++ E+T S P +
Sbjct: 616 GSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTH 675
Query: 752 TSPISNSSINERMAHQ---QRKSPSVSEEPLSPQKDESSATAKPLGENLTSQQKNLSNTP 808
T+ S+ ++ + SP ++ LSP S TA LG T+ +T
Sbjct: 676 TTAFPGSTTMPGLSQESTASHSSPGPTDTTLSP----GSTTASSLGPEYTTFHSRPGSTE 731
Query: 809 EPIIMSSSSIAPEAFPSEDLHNKTLSQQTCKSHVDTEKPYPASIPELASTEMIKVKNHSV 868
++ +++ + S +H+ T S T T P ++ + ST HS
Sbjct: 732 TTLLPDNTTASGLLEASMPVHSSTRSPHT------TLSPAGSTTRQGESTTF-----HSW 780
Query: 869 LQRTEKKVLPSPLELSVFSE-GTDNKG--NELPSAKLQDKQYIS--------------SV 911
+ + P P S F E T + G + +P+ + + S S
Sbjct: 781 PSSKDTRPAP-PTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGST 839
Query: 912 DKAPFSEGSRNKTHKQGSTQSRLETSHTSKSSEPSKS---------------------PD 950
F E + ST S T+HT S+ + S PD
Sbjct: 840 QTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPD 899
Query: 951 GIRNESRDSEISKRKTAEQHSFGICKEKRAR---IEDDQSTRNISSSS------PPEKEQ 1001
R E + +++ + I R+ + + +T ISS S P
Sbjct: 900 SSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTT 959
Query: 1002 PPREE--------PRVPPLKIQLSKIGPPFIIKSQPVSKPESRASTSTSVSGGRNTGA-- 1051
P E PR P + P S VS+ ++TS S G +T A
Sbjct: 960 PGLSERSTTFHSSPRSPATTLS------PASTTSSGVSE---ESTTSRSRPGSTHTTAFP 1010
Query: 1052 -RTLADIKARAQQARAQREAAAAAAVAAAASIVSG----AMGSPGEGGKTRTLAHIKEQT 1106
T +R + + A++ SG + S G T T A T
Sbjct: 1011 DSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDT-ALSPGST 1069
Query: 1107 KAKLFAKHQARAHLFQTSKETRLPPPLSSKEGPPNLEVSSTPETKMEGSTGVIIVNPNCR 1166
A F + H S T L P ++ G + +ST GS + +
Sbjct: 1070 TALSFGQESTTFHSNPGSTHTTLFPDSTTSSG---IVEASTRVHSSTGSPRTTLSPASST 1126
Query: 1167 SPSNKSAHLRETTTVLQQSLNPSKLPETAT-----DLSVHSSDENIPVSHLSEKIVSSTS 1221
SP + T PS P TAT + H S + P +H SST+
Sbjct: 1127 SPGLQGESTAFQTHPASTHTTPSP-PSTATAPVEESTTYHRSPGSTPTTHFP---ASSTT 1182
Query: 1222 SENSSVPMLFNKN-----SVPVSVCSTA----------ISGAIKEHPFVSSVDKSSVLMS 1266
S +S +F+ + + P S ST IS E ++++ S+
Sbjct: 1183 SGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTE---ITTLPGSTTTPG 1239
Query: 1267 VDSANTTISACNISMLKTIQGTDTPCIAIIPKCIES-----TPISATTEGSSISSSMDDK 1321
+ A+TT + S T+ + + + S + S + S+ + + ++
Sbjct: 1240 LSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEE 1299
Query: 1322 QLLISSSSASNLVSTQYTSVPTPSIGNNLPN------LSTSSVLIPPMGINNRFPSEKIA 1375
+ SSS + +T + T S+ P ST + L + E A
Sbjct: 1300 STTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTA 1359
Query: 1376 IPGSEEQATVSMGTTVRAALSCSDSVAVTDSLVAHPTVAMFTGNMLTINSYDSPPKLSAE 1435
PGS S T + A L+ +D + + P+ + TG L SP + +
Sbjct: 1360 FPGS----PASTQTGLPATLTTAD---LGEESTTFPSSSGSTGTKL------SPARSTTS 1406
Query: 1436 SLDKNSGPRNRADNSGKPQQPPGGFAPAAINRSIPCKVIVDHSTTLTSSLSLTVSVESSE 1495
L S P + +S + PG +++ S T S + T S SE
Sbjct: 1407 GLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSE 1466
Query: 1496 ASLDLQGRPVRTEASVQPVACPQVSVISRPEPVANEGIDHSSTFIAASAAKQDSKTLPAT 1555
S +P T + P + + P ST S + +L
Sbjct: 1467 ESSTSHSQPGSTHTTAFPDSTTTSDLSQEP---TTSHSSQGSTEATLSPGSTTASSLGQQ 1523
Query: 1556 CTSLRELP------LVPDK-----LNEPTAPSHN 1578
T+ P L+PD L E + P+H+
Sbjct: 1524 STTFHSSPGDTETTLLPDDTITSGLVEASTPTHS 1557
Score = 66.6 bits (161), Expect = 3e-10
Identities = 186/904 (20%), Positives = 313/904 (34%), Gaps = 145/904 (16%)
Query: 546 STSSMTHVSDTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMELQSDPEEQLSEN 605
+T+ ++ S T + + T +P T S E + M + P
Sbjct: 4323 TTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSMHTTAFPSSTTMPG 4382
Query: 606 ACISETSFSSESPEGACTSLPSPGGETQSTSEESCTPASLETTFCSEVSSTENTDKYNQR 665
+S+ S +S S G+ + SPG ST+ S P S TTF S STE T +
Sbjct: 4383 --VSQESTASHSSPGSTDTTLSPG----STTASSLGPES--TTFHSSPGSTETTLLPDNT 4434
Query: 666 NST-----DENFHASLMSE---ISPISTSPEISEASLMSNLPLTSEASPVS--------N 709
++ H+S S +SP ++ E++ + P + + +P
Sbjct: 4435 TASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVE 4494
Query: 710 LPLTSETSPMSDLPLTSETSSVSSMLLTSETTFVSSLPLPSETSPISNSSINERMAHQQ- 768
L TS SP S P T ++S +++ + E+T V S P+ + T+P S + +
Sbjct: 4495 LSTTSHGSP-SSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEEST 4553
Query: 769 --RKSPSVSEEPLSPQKDESSATAKPLGENLTSQQKNLSNTP--------EPIIMSSS-- 816
SP ++ P+ + +S + + +S +S+ P EP SS
Sbjct: 4554 TYHSSPGSTQTMHFPESNTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPG 4613
Query: 817 SIAPEAFPSEDLHNKTLSQQTCKSHVDTEKPYPASIPELASTEMIKVKNHSVLQRTEKKV 876
S A FP + S+++ SH + +P ++T ++ + + T +
Sbjct: 4614 STATTHFPDSSTTSGR-SEESTASHSSQDATGTIVLPARSTTSVL------LGESTTSPI 4666
Query: 877 LPSPLELSVFSEGTDNKGNELPSAKLQDKQYISSVDKAPFSEGSRNKTHKQGSTQSRLET 936
+E + T G S SS FS S + ST
Sbjct: 4667 SSGSMETTALPGSTTTPGLSEKSTTFHSSP--SSTPTTHFSASSTTLGRSEESTTVHSSP 4724
Query: 937 SHTSKSSEPSKSP-DGIRNESRDSEISKRKTAEQH----SFGICKEKRARIEDDQSTRNI 991
T+ + P++S G+ ES S T H S + + +R +T I
Sbjct: 4725 VATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTI 4784
Query: 992 SSSSPPEKEQPPREEPRVPPLKIQLSKIGPPFIIKSQPVSKPESRASTSTSVSGGRNTGA 1051
SS PP EEP S P S + S++ SG
Sbjct: 4785 SS--PPSTTSALVEEPTS---------------YHSSPGSIATTHFPESSTTSG------ 4821
Query: 1052 RTLADIKARAQQARAQREAAAAAAVAAAASIVSGAMGSPGEGGKTRTLAHIKEQTK-AKL 1110
R++++ A SP G T AH + A+
Sbjct: 4822 --------RSEESTASHS-------------------SPDTNGITPLPAHFTTSGRIAES 4854
Query: 1111 FAKHQARAHLFQTSKETRLPPPLSSKEGPPNLEVSSTPETKMEGS--TGVIIVNPNCRSP 1168
+ + + T T P LS+K S +T S + I P
Sbjct: 4855 TTFYISPGSMETTLASTATTPGLSAKSTILYSSSRSPDQTLSPASMTSSSISGEPTSLYS 4914
Query: 1169 SNKSAHLRETTTVLQQSLNPSKLPETATDLSVHSSDENIPVSHLSEKIVSSTSSENSSVP 1228
+S H TT S S L + +T + HS + + I +S+ ++ + P
Sbjct: 4915 QAESTH----TTAFPASTTTSGLSQEST--TFHSKPGSTETTLSPGSITTSSFAQEFTTP 4968
Query: 1229 MLFNKNSVPVSVCSTAISGAIKEHPFVSSVDKSSVLMSVDSANTTISACNISMLKTIQGT 1288
+S P S ST +S A P +S + + T S N + + Q T
Sbjct: 4969 -----HSQPGSALST-VSPASTTVPGLSEESTTFYSSPGSTETTAFSHSNTMSIHSQQST 5022
Query: 1289 DTP-----CIAIIPKCIESTPISATTEGSSISSSMDDKQLLISSSSASNLVSTQYTSVPT 1343
P ++P + +T I E ++ SS D +T T +P
Sbjct: 5023 PFPDSPGFTHTVLPATLTTTDIGQ--ESTAFHSSSD---------------ATGTTPLPA 5065
Query: 1344 PSIGNNLPNLSTSSVLIPPMGINNRFPSEKIAIPGSEEQATVSMGTTVRAALSCSDSVAV 1403
S ++L T+ + P FP+ +EE TT + S + ++
Sbjct: 5066 RSTASDLVGEPTTFYISPSPTYTTLFPASSSTSGLTEE------STTFHTSPSFTSTIVS 5119
Query: 1404 TDSL 1407
T+SL
Sbjct: 5120 TESL 5123
Score = 59.3 bits (142), Expect = 4e-08
Identities = 242/1235 (19%), Positives = 426/1235 (34%), Gaps = 177/1235 (14%)
Query: 572 IKTGSSSLEGQFPNEGIAIDMELQSDPE-----EQLSENACISETSFSSESPEGACTSLP 626
++ S +G EG ++ + L E+ + I+ ++FS S T
Sbjct: 112 VEFASPGDDGDGRAEGFSLGLPLSEQARAAGAREKERQETVINHSTFSGFSQITGSTVNT 171
Query: 627 SPGGETQSTSEESCTPA-------SLETTFCSEVSSTEN-----TDKYNQRNSTDENF-- 672
S GG T S S S + + TF + ++T++ T+ + ST +
Sbjct: 172 SIGGNTTSASTPSSSDPFTTFSDYGVSVTFITGSTATKHFLDSSTNSGHSEESTVSHSGP 231
Query: 673 ----------HASLMSEISPISTSPEISEASLMSNLPLTSEASPVSNLPLTSETSPMSDL 722
H++ + TSP S + + LP ++ + +S T +SP S
Sbjct: 232 GATGTTLFPSHSATSVFVGEPKTSPITSASMETTALPGSTTTAGLSEKSTTFYSSPRSPD 291
Query: 723 PLTSETSSVSSMLLTSETTFVSSLPLPSETSPISNSSINERMAHQQRKS---PSVSEEPL 779
S + SS + TT S P P+ T +S+ ++ + S P ++ L
Sbjct: 292 RTLSPARTTSSGVSEKSTT-SHSRPGPTHTIAFPDSTTMPGVSQESTASHSIPGSTDTTL 350
Query: 780 SPQKDESSATAKPLGENLTSQQKNLSNTPEPIIMSSSSIAPEAFPSEDLHNKTLSQQTCK 839
SP + T LG T+ + T + +++ + S +H+ T S T
Sbjct: 351 SP----GTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEASTPVHSSTGSPHTTL 406
Query: 840 S---------HVDTEKPYPAS---IPELASTEMIKVKNHSVLQRTEKKVLPSPLELSVFS 887
S T + +P+S P + T VK + + PS + FS
Sbjct: 407 SPSSSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSS-----PSSTPTTHFS 461
Query: 888 EGTDNKGNELPSAKLQDKQYISSVDKAPFSEGSRNKTHKQ-------GSTQSR--LETSH 938
+ G+ S + ++ P + + GSTQ+ E+S
Sbjct: 462 ASSTTLGHSEESTPVHSSPVATATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPESST 521
Query: 939 TSKSSEPSKSPDGIRNESRDSEISKRKTAEQHSF--GICKEKRARIEDDQSTRNISSSSP 996
TS SE S + G ++ S S S+ + + D + S S
Sbjct: 522 TSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESK 581
Query: 997 PEKEQPPREEPRVPPLKIQLSKIGPPFIIKSQPVSKPESRASTSTSVSGGRNTGARTLAD 1056
P V P P ++ P S S T+ G +T L++
Sbjct: 582 ASHSSPDAMATTVLPAG------STPSVLVGDSTPSPISSGSMETTALPG-STTKPGLSE 634
Query: 1057 IKARAQQARAQREAAAAAAVAAAASIVSGAMGSPGEGGKTRTLAHIKEQTKAKLFAKHQA 1116
+ + A ++ + + S G T T A T L ++
Sbjct: 635 KSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGL-SQEST 693
Query: 1117 RAHLFQTSKETRLPP--PLSSKEGPPNLEVSSTPETKMEGSTGVIIVNPNCRSPSNKSAH 1174
+H +T L P +S GP S P GST ++ N + A
Sbjct: 694 ASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRP-----GSTETTLLPDNTTASGLLEAS 748
Query: 1175 L------RETTTVLQQSLNPSKLPETATDLSVHSSDEN--IPVSHLSEKIVSSTSSENSS 1226
+ R T L + + ++ E+ T S SS + P + S + ST+S S
Sbjct: 749 MPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGS- 807
Query: 1227 VPMLFNKNSVPVSVCS--TAISGAIKEHPFVSSVDKSSVLMSVDSANTT------ISACN 1278
+S+P + S + SG ++E S S+ M ++TT + +
Sbjct: 808 ------PSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSH 861
Query: 1279 ISMLKTIQGTDTPCIAII--PKCIESTPISATT---EGSSISSSMDDKQLLISSSSASNL 1333
S TI + A++ P S+P S T SS +S ++ S++S S+
Sbjct: 862 SSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEE----STASHSSQ 917
Query: 1334 VSTQYTSVPTPSIGNNLPNLSTSSVLIPPMGINNRFPSEKIAIPGSEEQATV------SM 1387
+T +P S + L ST+S + P PG E++T S
Sbjct: 918 DATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPG-STTTPGLSERSTTFHSSPRSP 976
Query: 1388 GTTVRAALSCSDSVAVTDSLVAHPTVAMFTGNMLTINSYDS--PPKLSAESLDKNSGPRN 1445
TT+ A + S V+ + T G+ T DS P LS S +S P +
Sbjct: 977 ATTLSPASTTSSGVSEEST-----TSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGS 1031
Query: 1446 RADNSGKPQQPPGGFAPAAINRSIPC-KVIVDHSTTLTSSLSL----TVSVESSEASLDL 1500
PA+ S P + HS++ ++ +L T ++ + S
Sbjct: 1032 TDTT----------LLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTF 1081
Query: 1501 QGRPVRTEASVQPVACPQVSVISRPEPVANEGIDHSSTFIAASAAKQDSKTLPATCTSLR 1560
P T ++ P+ + GI +ST + +S + PA+ TS
Sbjct: 1082 HSNPGSTHTTL------------FPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTS-- 1127
Query: 1561 ELPLVPDKLNEPTAPSHNFAEQARGPAPFKSEADTTCSNQYNPSNRICWNDDGMRSTGQP 1620
P E TA + A P+P +T + S + +T P
Sbjct: 1128 -----PGLQGESTAFQTHPASTHTTPSP-----PSTATAPVEESTTYHRSPGSTPTTHFP 1177
Query: 1621 LVTHSGSSKQKEYLEQSCPKAIKTEHANYLNVSELHPRNLVTNVALPVKSELHEADKGFR 1680
+ + +K + S P A T ++ + + + + ++ P +E+
Sbjct: 1178 ASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRIS-PGSTEI-------- 1228
Query: 1681 MDTEDFPGPELPPPAAEGASSVQQTQNMKASTSSP 1715
PG P +E +++ + +T SP
Sbjct: 1229 ---TTLPGSTTTPGLSEASTTFYSSPRSPTTTLSP 1260
Score = 39.7 bits (91), Expect = 0.034
Identities = 55/175 (31%), Positives = 76/175 (43%), Gaps = 20/175 (11%)
Query: 608 ISETSFSSE-----SPEGACTSLPSPGGET-QSTSEESCT----PASLETTFCSE----- 652
I+ +SF+ E S G+ S SP T SEES T P S ETT S
Sbjct: 4956 ITTSSFAQEFTTPHSQPGSALSTVSPASTTVPGLSEESTTFYSSPGSTETTAFSHSNTMS 5015
Query: 653 VSSTENTDKYNQRNSTDENFHASLMS-EISPISTS-PEISEASLMSNLPLTSEASPVSNL 710
+ S ++T + T A+L + +I ST+ S+A+ + LP S AS +
Sbjct: 5016 IHSQQSTPFPDSPGFTHTVLPATLTTTDIGQESTAFHSSSDATGTTPLPARSTASDLVGE 5075
Query: 711 PLTSETSPMSDLPLTSETSSVSSMLLTSETTFVSSLPLPSETSPISNSSINERMA 765
P T SP SS +S L TTF +S PS TS I ++ E +A
Sbjct: 5076 PTTFYISPSPTYTTLFPASSSTSGLTEESTTFHTS---PSFTSTIVSTESLETLA 5127
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 84.0 bits (206), Expect = 2e-15
Identities = 212/1012 (20%), Positives = 365/1012 (36%), Gaps = 122/1012 (12%)
Query: 381 AQSSSSCGTSGLPVSAQTALAEQQPKSMKSPA---SPEPGFCATLCPMVE---IPPKDIM 434
+ SS G P + + +SPA +P PG + P V+ +PP
Sbjct: 204 SSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRA 263
Query: 435 AELESEDILIPEESVIQEEIAEEVETSICECQDENHKTIPEFSEEAESLTNSHEEPQIAP 494
+ E E E S +EE + + E + S A+ P AP
Sbjct: 264 KKPEEESESSEEGSESEEEAPAGTRSQVKA--SEKILQVRAASAPAKGTPGKGATP--AP 319
Query: 495 PEDNLESCVMMNDVLETLPHIEVKIEGKSESPQEEMTVVIDQLEVCDSLIPSTSSMTHVS 554
P ++ + + P + + + S EE T L + +S +
Sbjct: 320 PG---KAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKAL--LQAKASGKTSQVGAA 374
Query: 555 DTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMELQSDPEEQLSENACISETSFS 614
KES P KTG + + Q + + QS EE SE ++ S
Sbjct: 375 SAPAKESPRKGAAPAPPGKTGPAVAKAQAGKR----EEDSQSSSEESDSEEEAPAQAKPS 430
Query: 615 SESPEGACTSLP---SPGGETQSTSEESCTPASLETTFCSEVSSTENTDKYNQRNSTDEN 671
++P+ S P SP PA+ + + + ++ + + +S E
Sbjct: 431 GKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSE--ESDSDREA 488
Query: 672 FHASLMSEISPISTSPEISEASLMSNLPLTSEASPVSNLPLTSETSPMSDLPLTSETSSV 731
A +++ P+ SP++ AS M PL A PV + T P + + E S
Sbjct: 489 LAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPAT-PSAQVGKWEEDSES 547
Query: 732 SSMLLTSETTFVSSLPLPSETSPISNSSINERMAHQQRKSPSVSEEPLSPQKDESSATAK 791
SS E++ S +P+ +P S+ + + SP+ + K
Sbjct: 548 SS----EESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEK 603
Query: 792 PLGENLTSQQKNLSNTPE--PIIMSSSSIAP-------EAFPSEDLHNKTLSQQTCKSHV 842
P+ + +S++ + S E P M+++ P +A P + N T S + V
Sbjct: 604 PMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKT--NTTASAKVAPVRV 661
Query: 843 DTEKPYPA--------SIPELASTEMIKVKNHSVLQRTEKKVLPSPLELSVFSEGTDNKG 894
T+ P A S P +A ++ S + ++ + + L ++V + KG
Sbjct: 662 GTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKG 721
Query: 895 NELPSAKLQDKQYISSVDKAPFSEGSRNKTHKQGSTQSRLETSHTSKSSEPSKSPDGIRN 954
++ +A + K + AP G T TQ + E S+SSE +
Sbjct: 722 LQVKAASVPVKGSLGQ-GTAPVLPGKTGPT----VTQVKAEKQEDSESSEEESDSEEAAA 776
Query: 955 ESRDSEISKRKTAEQHSFGICKEKRARIEDDQSTRNISSSS-----PPEKEQPPREEPRV 1009
+ S +KT + + + A+ + +++++ P K +PP P+
Sbjct: 777 SPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQN 836
Query: 1010 PPL----KIQLSKIGPPFIIKSQPVSKPESRASTSTSVSGGRNTGARTLADIK--ARAQQ 1063
+ + +G +Q + PE + +S S A TLA +K + Q
Sbjct: 837 STVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEE-AETLAQVKPSGKTHQ 895
Query: 1064 ARAQREAAAAAAVAAAASIVSGAMG-SPGEGGKTRTLAHIKEQTKAKLFAKHQARAHLFQ 1122
RA A + AA G G S + GK E++ + A
Sbjct: 896 IRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDS------DGEAPAAV 949
Query: 1123 TSKETRLPPPLSSKEGPPNLEVSSTPETKMEGSTGVIIVNPNCRSPSNKSAHLRETTTVL 1182
TS + PP +I V+PN RSP+ +A T
Sbjct: 950 TSAQVIKPP--------------------------LIFVDPN-RSPAGPAA----TPAQA 978
Query: 1183 QQSLNPSKL---PETATDLSVHSSDEN-IPVSH-LSEKIVSSTSSENSSVPMLFNKNSV- 1236
Q + P K TA S S DE+ IP + L+ I ++ + ++ P + K S+
Sbjct: 979 QAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMA 1038
Query: 1237 --PVSVCSTAISGAIKEHPFVSSVDKS-SVLMSVDSANTTISACNISMLKTIQGTDTPCI 1293
S S+ IS K+ + VD + L + +T++ A + L+ P +
Sbjct: 1039 GASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRK---PKLPEV 1095
Query: 1294 AIIPKCIESTPISATTEGSSISSSMDDKQLLISSSSASNLVSTQYTSVPTPS 1345
K ES+ S + SS S S +D + + SA LV PTPS
Sbjct: 1096 QQATKAPESSDDSEDSSDSS-SGSEEDGEGPQGAKSAHTLVG------PTPS 1140
Score = 40.4 bits (93), Expect = 0.020
Identities = 183/973 (18%), Positives = 331/973 (34%), Gaps = 164/973 (16%)
Query: 631 ETQSTSEESCTPASLETTFCSEVSSTENTDKYNQRNSTDENFHASLMSEISPISTSPEIS 690
E + S + C A T + + T + ++ +E+ A+L ++ + +S S
Sbjct: 29 EVKEQSGQKCFLAQ-PVTLLDIYTHWQQTSELGRKRKAEED--AALQAKKTRVSDPISTS 85
Query: 691 EASLMSNLPLTSEASPVSNLPLTSETSPMSDLPLTSETSSVSSMLLTSETTFVSSLPLPS 750
E+S A L T+ + +DLP + + + + +T +S+P P+
Sbjct: 86 ESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTG--NSMPHPA 143
Query: 751 ETSPISNSSINERMAHQQRKSPSVSEEPLSPQKDESS-----ATAKP----LGENLTSQQ 801
++N + + ++ PS + +S ++E S A AKP G+ +S +
Sbjct: 144 TGKTVAN--LLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSE 201
Query: 802 KNLSNTPEPIIMSSSSIAPEAFPSEDLHNKTLSQQTCKSHVDTEKPYPASIPELASTEMI 861
S++ E + S+ P K S T +S P P + ++ T +
Sbjct: 202 DTSSSSDETDVEGKPSVKPAQV-------KASSVSTKESPARKAAPAPGKVGDV--TPQV 252
Query: 862 KVKNHSVLQRTEKKVLPSPLELSVFSEGTDNKGNELPSAKLQDKQYISSVDKAPFSEGSR 921
K +R +K P E S SE E P+ + + + +
Sbjct: 253 KGGALPPAKRAKK-----PEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPA 307
Query: 922 NKTHKQGSTQSRLETSHTSKSSEPSKSPDGIRNESRDSEISKRKTAEQHSFGICKEKRAR 981
T +G+T + + S + P+ DSE S ++++ + +
Sbjct: 308 KGTPGKGATPAPPGKAGAVASQTKAGKPE------EDSESSSEESSDSEEETPAAKALLQ 361
Query: 982 IEDDQSTRNISSSSPPEKEQPPREEPRVPPLKIQLSKIGPPFIIKSQPVSKPESRASTST 1041
+ T + ++S P KE P + PP K GP + K+Q + E S+S
Sbjct: 362 AKASGKTSQVGAASAPAKESPRKGAAPAPP-----GKTGPA-VAKAQAGKREEDSQSSSE 415
Query: 1042 SVSGGRNTGARTLADIKARAQQARAQREAAAAAAVAAAASIVSGAMGSPGEGGKTRTLAH 1101
A+ A +A Q RA A+A A + A P + G
Sbjct: 416 ESDSEEEAPAQ--AKPSGKAPQVRA------ASAPAKESPRKGAAPAPPRKTGPAAAQVQ 467
Query: 1102 IKEQTKAKLFAKHQARAHLFQTSKETRLPPPLSSKEGPPNLEVSSTPETKMEGSTGVIIV 1161
+ +Q + +R+ ++ + +++ + P + +P+ K + G+
Sbjct: 468 VGKQ-------EEDSRSSSEESDSDREALAAMNAAQVKP---LGKSPQVKPASTMGM--- 514
Query: 1162 NPNCRSPSNKSAHLRETTTVLQQSLNPSKLPETATDLSVHSSDENIPVSHLSEKIVSSTS 1221
P K A + P K+ V +E+ S +S
Sbjct: 515 -----GPLGKGAG----------PVPPGKVGPATPSAQVGKWEED-----------SESS 548
Query: 1222 SENSSVPMLFNKNSVPVSVCSTAISGAIKEHPFVSSVDKSSVLMSVDSANTTISACNISM 1281
SE SS + VP +V +KS L ++ A T S
Sbjct: 549 SEESSDS---SDGEVPTAVAPAQ--------------EKS--LGNILQAKPTSSPAKGPP 589
Query: 1282 LKTIQGTDTPCIAIIPKCIESTPISATTEGSSISSSMDDKQLLISSSSASNLVSTQYTSV 1341
K +A+ K + S ++E SS S+ ++ ++++ A + T
Sbjct: 590 QKAGP------VAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKA 643
Query: 1342 PTPSIGNNLPNLSTSSVLIPPMGINNRFPSEKIAIPGSEEQATVSMGTTVRAALSCSDSV 1401
P N +T+S + P+ + + P + + G T R A S S
Sbjct: 644 -CPKKTN-----TTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSE 697
Query: 1402 AVTDSLVAHPTVAMFTGNMLTINSYDSPPKLSAESLDKNSGPRNRADNSGKPQQPPGGFA 1461
+DS +A+ G ++ + S P + G PG
Sbjct: 698 E-SDSEEEKTGLAVTVGQAKSVGK--------GLQVKAASVPVKGSLGQGTAPVLPGKTG 748
Query: 1462 PAAINRSIPCKVIVDHSTTLTSSLSLTVSVESSEASLDLQGRPVRTEASVQPVACPQVSV 1521
P +V + SS + S E++ + ++ +T+A P A S
Sbjct: 749 PTVT------QVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSA 802
Query: 1522 ---ISRPEPVANEGIDHSSTFIAASAAKQDSKTLPATCTSLRELPLVPDKLNEPTAPSHN 1578
IS P V AA+ AKQ S P K+ P N
Sbjct: 803 KGTISAPGKVVT----------AAAQAKQRS----------------PSKVKPPVRNPQN 836
Query: 1579 FAEQARGPAPFKS 1591
ARGPA S
Sbjct: 837 STVLARGPASVPS 849
Score = 38.9 bits (89), Expect = 0.058
Identities = 197/1090 (18%), Positives = 366/1090 (33%), Gaps = 175/1090 (16%)
Query: 496 EDNLESCVMMNDV--LETLPHIEVKIE-GKSESPQEEMTVVIDQLEVCDSLIPSTSSMTH 552
E + + C + V L+ H + E G+ +E+ + + V D + S SS
Sbjct: 32 EQSGQKCFLAQPVTLLDIYTHWQQTSELGRKRKAEEDAALQAKKTRVSDPISTSESS--- 88
Query: 553 VSDTEHKESETAVETSTPKIK-TGSSSLEGQFPNEGIAIDMELQSDPEEQLSENACISET 611
E +E+E +TP++ T SS L P+ S E+ +E +T
Sbjct: 89 ---EEEEEAEAETAKATPRLASTNSSVLGADLPS----------SMKEKAKAETEKAGKT 135
Query: 612 SFSSESPEGACTSLPSPGGETQSTSEESCTPASLETTFCSEVSSTENTDKY--------- 662
S P T G++ S E S TT SE + +
Sbjct: 136 GNSMPHPATGKTVANLLSGKSPRKSAE----PSANTTLVSETEEEGSVPAFGAAAKPGMV 191
Query: 663 --NQRNSTDENFHASLMSEISPISTSPEISEASLMSNLPLTSE-----ASPVSN------ 709
Q +S+ E+ +S S+ + + P + A + ++ T E A+P
Sbjct: 192 SAGQADSSSEDTSSS--SDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVT 249
Query: 710 -------LPLTSETSPMSDLPLTSETSSVS---------SMLLTSETTF-VSSLPLPSET 752
LP + +SE S S S + SE V + P++
Sbjct: 250 PQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKG 309
Query: 753 SPISNSS----------INERMAHQQRKSPSVSEEPLSPQKDESSATAKPLGENLTSQQK 802
+P ++ ++ A + + S E S ++E+ A L + +
Sbjct: 310 TPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTS 369
Query: 803 NLSNTPEPIIMSSSSIAPEAFPSE--------DLHNKTLSQQTCKSHVDTEKPYPASIPE 854
+ P S A A P + + Q+ D+E+ PA
Sbjct: 370 QVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKP 429
Query: 855 LASTEMIKVKNHSVLQRTEKKVLPSP--------LELSVFSEGTDNKGNELPSAKLQDKQ 906
++ + + K P+P ++ V + D++ + S D++
Sbjct: 430 SGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESD--SDRE 487
Query: 907 YISSVDKAPFSEGSRNKTHKQGSTQSRLETSHTSKSSEPSKSPDGIRNESRDSEISKRKT 966
+++++ A ++ K ST + K + P P + + +++ K
Sbjct: 488 ALAAMNAAQVKPLGKSPQVKPAST---MGMGPLGKGAGP-VPPGKVGPATPSAQVGK--- 540
Query: 967 AEQHSFGICKEKRARIEDDQSTRNISSSSPPEKEQP----PREEPRVPPLKIQLSKIGPP 1022
E+ S E + D S + ++ P +E+ + +P P K K GP
Sbjct: 541 WEEDS-----ESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPV 595
Query: 1023 FI-IKSQ-PVSKPESRASTSTSVSGGRNTGARTLADIK------------------ARAQ 1062
+ +K++ P+ ES +S S A T A K A A+
Sbjct: 596 AVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAK 655
Query: 1063 QA------RAQREAAAAAAVAAAASIVSGAMGSPGEGGKTRTLAHIKEQT--------KA 1108
A +A R+A A + A ++ V+G P E + + +E+ +A
Sbjct: 656 VAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQA 715
Query: 1109 KLFAKH---QARAHLFQTSKETRLPPPLSSKEGPPNLEVSSTPETKMEGSTGVIIVNPNC 1165
K K +A + + S P L K GP +V + + E S
Sbjct: 716 KSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAA 775
Query: 1166 RSPSNKSAHLRETTTVLQQSLNPSKLPETATDLSVHSSDENIPVSHLSE-----KIVSST 1220
SP+ +++T Q NP+ + ++ + + + + ++ K+
Sbjct: 776 ASPAQVKTSVKKT----QAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPV 831
Query: 1221 SSENSSVPMLFNKNSVPVSVCSTAISGAIKEHPFVSSVDKSSVLMSVDSANTTISACNIS 1280
+ +S + SVP + A + + P S S + A T
Sbjct: 832 RNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSG 891
Query: 1281 MLKTIQGTDTPCIAIIPKCIESTPISATTEGSSISSSMDDKQLLISSSSASNLVSTQYTS 1340
I+ P K TP T ++ + DD SSS S+
Sbjct: 892 KTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSG---SSSEESD-------- 940
Query: 1341 VPTPSIGNNLPNLSTSSVLIPPMGI--NNRFPSEKIAIPGSEEQATVSMGTTVRAALSCS 1398
S G ++++ V+ PP+ NR P+ A P + A+ + + S
Sbjct: 941 ----SDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARS 996
Query: 1399 DSVAVTDSLVAHPTVAMFTG---NMLTINSYDSPPKLSAESLDKNSGPRNRADNSGKPQQ 1455
S D V T + G N++T+ + A +S + + GK Q+
Sbjct: 997 SSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQE 1056
Query: 1456 PPGGFAPAAI 1465
P +A+
Sbjct: 1057 GPATQVDSAV 1066
Score = 32.3 bits (72), Expect = 5.4
Identities = 42/198 (21%), Positives = 79/198 (39%), Gaps = 20/198 (10%)
Query: 38 QKEGLKETSGTSP-----LACLNAMLHTNTRIGDGTFFKIPGKSG-----LYALKKEESS 87
+K GL T G + L A + +G GT +PGK+G + A K+E+S
Sbjct: 704 EKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSE 763
Query: 88 CPADGTLDLVCESELDGTDMAEANAHGEENGVCSKQVTDEASSTRDSSLTNTAVQSKLVS 147
E E D + A + A + + ++ + A++ S+ + K+V+
Sbjct: 764 SS---------EEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVT 814
Query: 148 SFQQHTKKALKQALRQQQKRRNGVSMMVNK-TVPRVVLTPLKVSDEQSDSPSGSESKNGE 206
+ Q +++ + + +N + +VP V + Q+ S S E
Sbjct: 815 AAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEE 874
Query: 207 ADSSDKEMKHGQKSPTGK 224
+DS ++ Q P+GK
Sbjct: 875 SDSEEEAETLAQVKPSGK 892
>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a [Homo
sapiens]
Length = 1450
Score = 82.8 bits (203), Expect = 3e-15
Identities = 207/1012 (20%), Positives = 364/1012 (35%), Gaps = 123/1012 (12%)
Query: 381 AQSSSSCGTSGLPVSAQTALAEQQPKSMKSPA---SPEPGFCATLCPMVE---IPPKDIM 434
+ SS G P + + +SPA +P PG + P V+ +PP
Sbjct: 204 SSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRA 263
Query: 435 AELESEDILIPEESVIQEEIAEEVETSICECQDENHKTIPEFSEEAESLTNSHEEPQIAP 494
+ E E E S +EE + + E + S A+ P AP
Sbjct: 264 KKPEEESESSEEGSESEEEAPAGTRSQVKA--SEKILQVRAASAPAKGTPGKGATP--AP 319
Query: 495 PEDNLESCVMMNDVLETLPHIEVKIEGKSESPQEEMTVVIDQLEVCDSLIPSTSSMTHVS 554
P ++ + + P + + + S EE T L + +S +
Sbjct: 320 PG---KAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKAL--LQAKASGKTSQVGAA 374
Query: 555 DTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMELQSDPEEQLSENACISETSFS 614
KES P KTG + + Q + + QS EE SE ++ S
Sbjct: 375 SAPAKESPRKGAAPAPPGKTGPAVAKAQAGKR----EEDSQSSSEESDSEEEAPAQAKPS 430
Query: 615 SESPEGACTSLP---SPGGETQSTSEESCTPASLETTFCSEVSSTENTDKYNQRNSTDEN 671
++P+ S P SP PA+ + + + ++ + + +S E
Sbjct: 431 GKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSE--ESDSDREA 488
Query: 672 FHASLMSEISPISTSPEISEASLMSNLPLTSEASPVSNLPLTSETSPMSDLPLTSETSSV 731
A +++ P+ SP++ AS M PL A PV + T P + + E S
Sbjct: 489 LAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPAT-PSAQVGKWEEDSES 547
Query: 732 SSMLLTSETTFVSSLPLPSETSPISNSSINERMAHQQRKSPSVSEEPLSPQKDESSATAK 791
SS E++ S +P+ +P S+ + + SP+ + K
Sbjct: 548 SS----EESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEK 603
Query: 792 PLGENLTSQQKNLSNTPE--PIIMSSSSIAP-------EAFPSEDLHNKTLSQQTCKSHV 842
P+ + +S++ + S E P M+++ P +A P + N T S + V
Sbjct: 604 PMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKT--NTTASAKVAPVRV 661
Query: 843 DTEKPYPA--------SIPELASTEMIKVKNHSVLQRTEKKVLPSPLELSVFSEGTDNKG 894
T+ P A S P +A ++ S + ++ + + L ++V + KG
Sbjct: 662 GTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKG 721
Query: 895 NELPSAKLQDKQYISSVDKAPFSEGSRNKTHKQGSTQSRLETSHTSKSSEPSKSPDGIRN 954
++ +A + K + AP G T TQ + E S+SSE +
Sbjct: 722 LQVKAASVPVKGSLGQ-GTAPVLPGKTGPT----VTQVKAEKQEDSESSEEESDSEEAAA 776
Query: 955 ESRDSEISKRKTAEQHSFGICKEKRARIEDDQSTRNISSSS-----PPEKEQPPREEPRV 1009
+ S +KT + + + A+ + +++++ P K +PP P+
Sbjct: 777 SPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQN 836
Query: 1010 PPL----KIQLSKIGPPFIIKSQPVSKPESRASTSTSVSGGRNTGARTLADIK--ARAQQ 1063
+ + +G +Q + PE + +S S A TLA +K + Q
Sbjct: 837 STVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEE-AETLAQVKPSGKTHQ 895
Query: 1064 ARAQREAAAAAAVAAAASIVSGAMG-SPGEGGKTRTLAHIKEQTKAKLFAKHQARAHLFQ 1122
RA A + AA G G S + GK E++ + A
Sbjct: 896 IRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDS------DGEAPAAV 949
Query: 1123 TSKETRLPPPLSSKEGPPNLEVSSTPETKMEGSTGVIIVNPNCRSPSNKSAHLRETTTVL 1182
TS + PP +I V+PN RSP+ +A T
Sbjct: 950 TSAQVIKPP--------------------------LIFVDPN-RSPAGPAA----TPAQA 978
Query: 1183 QQSLNPSKL---PETATDLSVHSSDEN-IPVSH-LSEKIVSSTSSENSSVPMLFNKNSV- 1236
Q + P K TA S S DE+ IP + L+ I ++ + ++ P + K S+
Sbjct: 979 QAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMA 1038
Query: 1237 --PVSVCSTAISGAIKEHPFVSSVDKS-SVLMSVDSANTTISACNISMLKTIQGTDTPCI 1293
S S+ IS K+ + VD + L + +T++ A + L+ P +
Sbjct: 1039 GASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLR------KPKL 1092
Query: 1294 AIIPKCIESTPISATTEGSSISSSMDDKQLLISSSSASNLVSTQYTSVPTPS 1345
+ + ++ S +E SS SSS ++ + +T PTPS
Sbjct: 1093 PEVQQATKAPESSDDSEDSSDSSSGSEE-----DGEGPQGAKSAHTLGPTPS 1139
Score = 40.4 bits (93), Expect = 0.020
Identities = 183/973 (18%), Positives = 331/973 (34%), Gaps = 164/973 (16%)
Query: 631 ETQSTSEESCTPASLETTFCSEVSSTENTDKYNQRNSTDENFHASLMSEISPISTSPEIS 690
E + S + C A T + + T + ++ +E+ A+L ++ + +S S
Sbjct: 29 EVKEQSGQKCFLAQ-PVTLLDIYTHWQQTSELGRKRKAEED--AALQAKKTRVSDPISTS 85
Query: 691 EASLMSNLPLTSEASPVSNLPLTSETSPMSDLPLTSETSSVSSMLLTSETTFVSSLPLPS 750
E+S A L T+ + +DLP + + + + +T +S+P P+
Sbjct: 86 ESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTG--NSMPHPA 143
Query: 751 ETSPISNSSINERMAHQQRKSPSVSEEPLSPQKDESS-----ATAKP----LGENLTSQQ 801
++N + + ++ PS + +S ++E S A AKP G+ +S +
Sbjct: 144 TGKTVAN--LLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSE 201
Query: 802 KNLSNTPEPIIMSSSSIAPEAFPSEDLHNKTLSQQTCKSHVDTEKPYPASIPELASTEMI 861
S++ E + S+ P K S T +S P P + ++ T +
Sbjct: 202 DTSSSSDETDVEGKPSVKPAQV-------KASSVSTKESPARKAAPAPGKVGDV--TPQV 252
Query: 862 KVKNHSVLQRTEKKVLPSPLELSVFSEGTDNKGNELPSAKLQDKQYISSVDKAPFSEGSR 921
K +R +K P E S SE E P+ + + + +
Sbjct: 253 KGGALPPAKRAKK-----PEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPA 307
Query: 922 NKTHKQGSTQSRLETSHTSKSSEPSKSPDGIRNESRDSEISKRKTAEQHSFGICKEKRAR 981
T +G+T + + S + P+ DSE S ++++ + +
Sbjct: 308 KGTPGKGATPAPPGKAGAVASQTKAGKPE------EDSESSSEESSDSEEETPAAKALLQ 361
Query: 982 IEDDQSTRNISSSSPPEKEQPPREEPRVPPLKIQLSKIGPPFIIKSQPVSKPESRASTST 1041
+ T + ++S P KE P + PP K GP + K+Q + E S+S
Sbjct: 362 AKASGKTSQVGAASAPAKESPRKGAAPAPP-----GKTGPA-VAKAQAGKREEDSQSSSE 415
Query: 1042 SVSGGRNTGARTLADIKARAQQARAQREAAAAAAVAAAASIVSGAMGSPGEGGKTRTLAH 1101
A+ A +A Q RA A+A A + A P + G
Sbjct: 416 ESDSEEEAPAQ--AKPSGKAPQVRA------ASAPAKESPRKGAAPAPPRKTGPAAAQVQ 467
Query: 1102 IKEQTKAKLFAKHQARAHLFQTSKETRLPPPLSSKEGPPNLEVSSTPETKMEGSTGVIIV 1161
+ +Q + +R+ ++ + +++ + P + +P+ K + G+
Sbjct: 468 VGKQ-------EEDSRSSSEESDSDREALAAMNAAQVKP---LGKSPQVKPASTMGM--- 514
Query: 1162 NPNCRSPSNKSAHLRETTTVLQQSLNPSKLPETATDLSVHSSDENIPVSHLSEKIVSSTS 1221
P K A + P K+ V +E+ S +S
Sbjct: 515 -----GPLGKGAG----------PVPPGKVGPATPSAQVGKWEED-----------SESS 548
Query: 1222 SENSSVPMLFNKNSVPVSVCSTAISGAIKEHPFVSSVDKSSVLMSVDSANTTISACNISM 1281
SE SS + VP +V +KS L ++ A T S
Sbjct: 549 SEESSDS---SDGEVPTAVAPAQ--------------EKS--LGNILQAKPTSSPAKGPP 589
Query: 1282 LKTIQGTDTPCIAIIPKCIESTPISATTEGSSISSSMDDKQLLISSSSASNLVSTQYTSV 1341
K +A+ K + S ++E SS S+ ++ ++++ A + T
Sbjct: 590 QKAGP------VAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKA 643
Query: 1342 PTPSIGNNLPNLSTSSVLIPPMGINNRFPSEKIAIPGSEEQATVSMGTTVRAALSCSDSV 1401
P N +T+S + P+ + + P + + G T R A S S
Sbjct: 644 -CPKKTN-----TTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSE 697
Query: 1402 AVTDSLVAHPTVAMFTGNMLTINSYDSPPKLSAESLDKNSGPRNRADNSGKPQQPPGGFA 1461
+DS +A+ G ++ + S P + G PG
Sbjct: 698 E-SDSEEEKTGLAVTVGQAKSVGK--------GLQVKAASVPVKGSLGQGTAPVLPGKTG 748
Query: 1462 PAAINRSIPCKVIVDHSTTLTSSLSLTVSVESSEASLDLQGRPVRTEASVQPVACPQVSV 1521
P +V + SS + S E++ + ++ +T+A P A S
Sbjct: 749 PTVT------QVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSA 802
Query: 1522 ---ISRPEPVANEGIDHSSTFIAASAAKQDSKTLPATCTSLRELPLVPDKLNEPTAPSHN 1578
IS P V AA+ AKQ S P K+ P N
Sbjct: 803 KGTISAPGKVVT----------AAAQAKQRS----------------PSKVKPPVRNPQN 836
Query: 1579 FAEQARGPAPFKS 1591
ARGPA S
Sbjct: 837 STVLARGPASVPS 849
Score = 38.9 bits (89), Expect = 0.058
Identities = 197/1090 (18%), Positives = 366/1090 (33%), Gaps = 175/1090 (16%)
Query: 496 EDNLESCVMMNDV--LETLPHIEVKIE-GKSESPQEEMTVVIDQLEVCDSLIPSTSSMTH 552
E + + C + V L+ H + E G+ +E+ + + V D + S SS
Sbjct: 32 EQSGQKCFLAQPVTLLDIYTHWQQTSELGRKRKAEEDAALQAKKTRVSDPISTSESS--- 88
Query: 553 VSDTEHKESETAVETSTPKIK-TGSSSLEGQFPNEGIAIDMELQSDPEEQLSENACISET 611
E +E+E +TP++ T SS L P+ S E+ +E +T
Sbjct: 89 ---EEEEEAEAETAKATPRLASTNSSVLGADLPS----------SMKEKAKAETEKAGKT 135
Query: 612 SFSSESPEGACTSLPSPGGETQSTSEESCTPASLETTFCSEVSSTENTDKY--------- 662
S P T G++ S E S TT SE + +
Sbjct: 136 GNSMPHPATGKTVANLLSGKSPRKSAE----PSANTTLVSETEEEGSVPAFGAAAKPGMV 191
Query: 663 --NQRNSTDENFHASLMSEISPISTSPEISEASLMSNLPLTSE-----ASPVSN------ 709
Q +S+ E+ +S S+ + + P + A + ++ T E A+P
Sbjct: 192 SAGQADSSSEDTSSS--SDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVT 249
Query: 710 -------LPLTSETSPMSDLPLTSETSSVS---------SMLLTSETTF-VSSLPLPSET 752
LP + +SE S S S + SE V + P++
Sbjct: 250 PQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKG 309
Query: 753 SPISNSS----------INERMAHQQRKSPSVSEEPLSPQKDESSATAKPLGENLTSQQK 802
+P ++ ++ A + + S E S ++E+ A L + +
Sbjct: 310 TPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTS 369
Query: 803 NLSNTPEPIIMSSSSIAPEAFPSE--------DLHNKTLSQQTCKSHVDTEKPYPASIPE 854
+ P S A A P + + Q+ D+E+ PA
Sbjct: 370 QVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKP 429
Query: 855 LASTEMIKVKNHSVLQRTEKKVLPSP--------LELSVFSEGTDNKGNELPSAKLQDKQ 906
++ + + K P+P ++ V + D++ + S D++
Sbjct: 430 SGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESD--SDRE 487
Query: 907 YISSVDKAPFSEGSRNKTHKQGSTQSRLETSHTSKSSEPSKSPDGIRNESRDSEISKRKT 966
+++++ A ++ K ST + K + P P + + +++ K
Sbjct: 488 ALAAMNAAQVKPLGKSPQVKPAST---MGMGPLGKGAGP-VPPGKVGPATPSAQVGK--- 540
Query: 967 AEQHSFGICKEKRARIEDDQSTRNISSSSPPEKEQP----PREEPRVPPLKIQLSKIGPP 1022
E+ S E + D S + ++ P +E+ + +P P K K GP
Sbjct: 541 WEEDS-----ESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPV 595
Query: 1023 FI-IKSQ-PVSKPESRASTSTSVSGGRNTGARTLADIK------------------ARAQ 1062
+ +K++ P+ ES +S S A T A K A A+
Sbjct: 596 AVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAK 655
Query: 1063 QA------RAQREAAAAAAVAAAASIVSGAMGSPGEGGKTRTLAHIKEQT--------KA 1108
A +A R+A A + A ++ V+G P E + + +E+ +A
Sbjct: 656 VAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQA 715
Query: 1109 KLFAKH---QARAHLFQTSKETRLPPPLSSKEGPPNLEVSSTPETKMEGSTGVIIVNPNC 1165
K K +A + + S P L K GP +V + + E S
Sbjct: 716 KSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAA 775
Query: 1166 RSPSNKSAHLRETTTVLQQSLNPSKLPETATDLSVHSSDENIPVSHLSE-----KIVSST 1220
SP+ +++T Q NP+ + ++ + + + + ++ K+
Sbjct: 776 ASPAQVKTSVKKT----QAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPV 831
Query: 1221 SSENSSVPMLFNKNSVPVSVCSTAISGAIKEHPFVSSVDKSSVLMSVDSANTTISACNIS 1280
+ +S + SVP + A + + P S S + A T
Sbjct: 832 RNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSG 891
Query: 1281 MLKTIQGTDTPCIAIIPKCIESTPISATTEGSSISSSMDDKQLLISSSSASNLVSTQYTS 1340
I+ P K TP T ++ + DD SSS S+
Sbjct: 892 KTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSG---SSSEESD-------- 940
Query: 1341 VPTPSIGNNLPNLSTSSVLIPPMGI--NNRFPSEKIAIPGSEEQATVSMGTTVRAALSCS 1398
S G ++++ V+ PP+ NR P+ A P + A+ + + S
Sbjct: 941 ----SDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARS 996
Query: 1399 DSVAVTDSLVAHPTVAMFTG---NMLTINSYDSPPKLSAESLDKNSGPRNRADNSGKPQQ 1455
S D V T + G N++T+ + A +S + + GK Q+
Sbjct: 997 SSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQE 1056
Query: 1456 PPGGFAPAAI 1465
P +A+
Sbjct: 1057 GPATQVDSAV 1066
Score = 32.3 bits (72), Expect = 5.4
Identities = 42/198 (21%), Positives = 79/198 (39%), Gaps = 20/198 (10%)
Query: 38 QKEGLKETSGTSP-----LACLNAMLHTNTRIGDGTFFKIPGKSG-----LYALKKEESS 87
+K GL T G + L A + +G GT +PGK+G + A K+E+S
Sbjct: 704 EKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSE 763
Query: 88 CPADGTLDLVCESELDGTDMAEANAHGEENGVCSKQVTDEASSTRDSSLTNTAVQSKLVS 147
E E D + A + A + + ++ + A++ S+ + K+V+
Sbjct: 764 SS---------EEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVT 814
Query: 148 SFQQHTKKALKQALRQQQKRRNGVSMMVNK-TVPRVVLTPLKVSDEQSDSPSGSESKNGE 206
+ Q +++ + + +N + +VP V + Q+ S S E
Sbjct: 815 AAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEE 874
Query: 207 ADSSDKEMKHGQKSPTGK 224
+DS ++ Q P+GK
Sbjct: 875 SDSEEEAETLAQVKPSGK 892
Score = 32.3 bits (72), Expect = 5.4
Identities = 89/484 (18%), Positives = 178/484 (36%), Gaps = 69/484 (14%)
Query: 554 SDTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMELQSDPEEQLSENACISETSF 613
S++E ++ A + TP I+T ++ P M S +E S
Sbjct: 999 SESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKE--------SSRIS 1050
Query: 614 SSESPEGACTSLPSPGGETQSTSEESCTPASLETTFCSEVSSTENTDKYNQRNSTDENFH 673
+ EG T + S G +TS +S + + T + E S+D++
Sbjct: 1051 DGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSED 1110
Query: 674 ASLMSEISPISTSPEISEASLMSNLPLTSEASPVSNLPLTSETSP-MSDLPLTSETSSVS 732
+S S S S E E + T +P L ET+ S+ + + + S+
Sbjct: 1111 SSDSS-----SGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPSQSLL 1165
Query: 733 SMLLTSETTFVSSLPLPSETSPISNSSINERMAHQ------QRKSPSVSEEPLSPQKDES 786
S +T T +S + S+ S++ +A + Q P + LSP+
Sbjct: 1166 SGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGK 1225
Query: 787 SATAKPLGENLTSQQKNLSNTPEPIIMSSSSIAPEAFPSEDLHNKTLSQQTCKSHVDTEK 846
A + + +K N P+A TL+ Q+ + +
Sbjct: 1226 EAASGTTPQKSRKPKKGAGN-------------PQA--------STLALQSNITQCLLGQ 1264
Query: 847 PYPASIPELASTEMIKVKNHSVLQRTEKKVLPSPLELSVFSEGTDNKGNEL----PSAKL 902
P+P + ++ ++ ++KV +L++ KKV+ + E S +G +++ +L P+A+
Sbjct: 1265 PWPLNEAQVQAS-VVKVLTE-LLEQERKKVVDTTKESS--RKGWESRKRKLSGDQPAART 1320
Query: 903 Q--------------------DKQYISSVDKAPFSEGSRNKTHKQGSTQSRLETSHTSKS 942
+K +S KA + S + K+G + +
Sbjct: 1321 PRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPE 1380
Query: 943 SEPSKSPDGIRNESRDSEISKRKTAEQHSFGICKEKRARIEDDQSTRNISSSSPPEKEQP 1002
E K + + + SK++ + KEK+ + + + S SP +K++
Sbjct: 1381 EELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKK 1440
Query: 1003 PREE 1006
+++
Sbjct: 1441 KKKK 1444
>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
[Homo sapiens]
Length = 1488
Score = 81.3 bits (199), Expect = 1e-14
Identities = 205/1027 (19%), Positives = 362/1027 (35%), Gaps = 115/1027 (11%)
Query: 381 AQSSSSCGTSGLPVSAQTALAEQQPKSMKSPA---SPEPGFCATLCPMVE---IPPKDIM 434
+ SS G P + + +SPA +P PG + P V+ +PP
Sbjct: 204 SSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRA 263
Query: 435 AELESEDILIPEESVIQEEIAEEVETSICECQDENHKTIPEFSEEAESLTNSHEEPQIAP 494
+ E E E S +EE + + E + S A+ P AP
Sbjct: 264 KKPEEESESSEEGSESEEEAPAGTRSQVKA--SEKILQVRAASAPAKGTPGKGATP--AP 319
Query: 495 PEDNLESCVMMNDVLETLPHIEVKIEGKSESPQEEMTVVIDQLEVCDSLIPSTSSMTHVS 554
P ++ + + P + + + S EE T L + +S +
Sbjct: 320 PG---KAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKAL--LQAKASGKTSQVGAA 374
Query: 555 DTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMELQSDPEEQLSENACISETSFS 614
KES P KTG + + Q + + QS EE SE ++ S
Sbjct: 375 SAPAKESPRKGAAPAPPGKTGPAVAKAQAGKR----EEDSQSSSEESDSEEEAPAQAKPS 430
Query: 615 SESPEGACTSLP---SPGGETQSTSEESCTPASLETTFCSEVSSTENTDKYNQRNSTDEN 671
++P+ S P SP PA+ + + + ++ + + +S E
Sbjct: 431 GKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSE--ESDSDREA 488
Query: 672 FHASLMSEISPISTSPEISEASLMSNLPLTSEASPVSNLPLTSETSPMSDLPLTSETSSV 731
A +++ P+ SP++ AS M PL A PV + T P + + E S
Sbjct: 489 LAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPAT-PSAQVGKWEEDSES 547
Query: 732 SSMLLTSETTFVSSLPLPSETSPISNSSINERMAHQQRKSPSVSEEPLSPQKDESSATAK 791
SS E++ S +P+ +P S+ + + SP+ + K
Sbjct: 548 SS----EESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEK 603
Query: 792 PLGENLTSQQKNLSNTPE--PIIMSSSSIAP-------EAFPSEDLHNKTLSQQTCKSHV 842
P+ + +S++ + S E P M+++ P +A P + N T S + V
Sbjct: 604 PMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKT--NTTASAKVAPVRV 661
Query: 843 DTEKPYPA--------SIPELASTEMIKVKNHSVLQRTEKKVLPSPLELSVFSEGTDNKG 894
T+ P A S P +A ++ S + ++ + + L ++V + KG
Sbjct: 662 GTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKG 721
Query: 895 NELPSAKLQDKQYISSVDKAPFSEGSRNKTHKQGSTQSRLETSHTSKSSEPSKSPDGIRN 954
++ +A + K + AP G T TQ + E S+SSE +
Sbjct: 722 LQVKAASVPVKGSLGQ-GTAPVLPGKTGPT----VTQVKAEKQEDSESSEEESDSEEAAA 776
Query: 955 ESRDSEISKRKTAEQHSFGICKEKRARIEDDQSTRNISSSS-----PPEKEQPPREEPRV 1009
+ S +KT + + + A+ + +++++ P K +PP P+
Sbjct: 777 SPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQN 836
Query: 1010 PPL----KIQLSKIGPPFIIKSQPVSKPESRASTSTSVSGGRNTGARTLADIK--ARAQQ 1063
+ + +G +Q + PE + +S S A TLA +K + Q
Sbjct: 837 STVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEE-AETLAQVKPSGKTHQ 895
Query: 1064 ARAQREAAAAAAVAAAASIVSGAMG-SPGEGGKTRTLAHIKEQTKAKLFAKHQARAHLFQ 1122
RA A + AA G G S + GK E++ + A
Sbjct: 896 IRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDS------DGEAPAAV 949
Query: 1123 TSKETRLPP---------PLSSKEGPPNLEVSSTP-----------ETKMEGSTGVIIVN 1162
TS + PP P P + +STP + E +I
Sbjct: 950 TSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPA 1009
Query: 1163 PNCRSPSNKSAHLRETTTVLQQSLNPSKLPETATDLSVHSSDENIPVS--HLSEKIVSST 1220
C +P + T V + +P P+ A+ SS E+ +S E +
Sbjct: 1010 TQCLTPGIR------TNVVTMPTAHPRIAPK-ASMAGASSSKESSRISDGKKQEGPATQV 1062
Query: 1221 SSEN-SSVPMLFNKNSVPVSVCSTAISGAIKEHPFVSSVDKS-SVLMSVDSANTTISACN 1278
S +N +S+P+ V S A + P S VD + L + +T++ A
Sbjct: 1063 SKKNPASLPLTQAALKVLAQKASEAQPPVARTQP-SSGVDSAVGTLPATSPQSTSVQAKG 1121
Query: 1279 ISMLKTIQGTDTPCIAIIPKCIESTPISATTEGSSISSSMDDKQLLISSSSASNLVSTQY 1338
+ L+ P + + + ++ S +E SS SSS ++ + +
Sbjct: 1122 TNKLR------KPKLPEVQQATKAPESSDDSEDSSDSSSGSEE-----DGEGPQGAKSAH 1170
Query: 1339 TSVPTPS 1345
T PTPS
Sbjct: 1171 TLGPTPS 1177
Score = 40.4 bits (93), Expect = 0.020
Identities = 183/973 (18%), Positives = 331/973 (34%), Gaps = 164/973 (16%)
Query: 631 ETQSTSEESCTPASLETTFCSEVSSTENTDKYNQRNSTDENFHASLMSEISPISTSPEIS 690
E + S + C A T + + T + ++ +E+ A+L ++ + +S S
Sbjct: 29 EVKEQSGQKCFLAQ-PVTLLDIYTHWQQTSELGRKRKAEED--AALQAKKTRVSDPISTS 85
Query: 691 EASLMSNLPLTSEASPVSNLPLTSETSPMSDLPLTSETSSVSSMLLTSETTFVSSLPLPS 750
E+S A L T+ + +DLP + + + + +T +S+P P+
Sbjct: 86 ESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTG--NSMPHPA 143
Query: 751 ETSPISNSSINERMAHQQRKSPSVSEEPLSPQKDESS-----ATAKP----LGENLTSQQ 801
++N + + ++ PS + +S ++E S A AKP G+ +S +
Sbjct: 144 TGKTVAN--LLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSE 201
Query: 802 KNLSNTPEPIIMSSSSIAPEAFPSEDLHNKTLSQQTCKSHVDTEKPYPASIPELASTEMI 861
S++ E + S+ P K S T +S P P + ++ T +
Sbjct: 202 DTSSSSDETDVEGKPSVKPAQV-------KASSVSTKESPARKAAPAPGKVGDV--TPQV 252
Query: 862 KVKNHSVLQRTEKKVLPSPLELSVFSEGTDNKGNELPSAKLQDKQYISSVDKAPFSEGSR 921
K +R +K P E S SE E P+ + + + +
Sbjct: 253 KGGALPPAKRAKK-----PEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPA 307
Query: 922 NKTHKQGSTQSRLETSHTSKSSEPSKSPDGIRNESRDSEISKRKTAEQHSFGICKEKRAR 981
T +G+T + + S + P+ DSE S ++++ + +
Sbjct: 308 KGTPGKGATPAPPGKAGAVASQTKAGKPE------EDSESSSEESSDSEEETPAAKALLQ 361
Query: 982 IEDDQSTRNISSSSPPEKEQPPREEPRVPPLKIQLSKIGPPFIIKSQPVSKPESRASTST 1041
+ T + ++S P KE P + PP K GP + K+Q + E S+S
Sbjct: 362 AKASGKTSQVGAASAPAKESPRKGAAPAPP-----GKTGPA-VAKAQAGKREEDSQSSSE 415
Query: 1042 SVSGGRNTGARTLADIKARAQQARAQREAAAAAAVAAAASIVSGAMGSPGEGGKTRTLAH 1101
A+ A +A Q RA A+A A + A P + G
Sbjct: 416 ESDSEEEAPAQ--AKPSGKAPQVRA------ASAPAKESPRKGAAPAPPRKTGPAAAQVQ 467
Query: 1102 IKEQTKAKLFAKHQARAHLFQTSKETRLPPPLSSKEGPPNLEVSSTPETKMEGSTGVIIV 1161
+ +Q + +R+ ++ + +++ + P + +P+ K + G+
Sbjct: 468 VGKQ-------EEDSRSSSEESDSDREALAAMNAAQVKP---LGKSPQVKPASTMGM--- 514
Query: 1162 NPNCRSPSNKSAHLRETTTVLQQSLNPSKLPETATDLSVHSSDENIPVSHLSEKIVSSTS 1221
P K A + P K+ V +E+ S +S
Sbjct: 515 -----GPLGKGAG----------PVPPGKVGPATPSAQVGKWEED-----------SESS 548
Query: 1222 SENSSVPMLFNKNSVPVSVCSTAISGAIKEHPFVSSVDKSSVLMSVDSANTTISACNISM 1281
SE SS + VP +V +KS L ++ A T S
Sbjct: 549 SEESSDS---SDGEVPTAVAPAQ--------------EKS--LGNILQAKPTSSPAKGPP 589
Query: 1282 LKTIQGTDTPCIAIIPKCIESTPISATTEGSSISSSMDDKQLLISSSSASNLVSTQYTSV 1341
K +A+ K + S ++E SS S+ ++ ++++ A + T
Sbjct: 590 QKAGP------VAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKA 643
Query: 1342 PTPSIGNNLPNLSTSSVLIPPMGINNRFPSEKIAIPGSEEQATVSMGTTVRAALSCSDSV 1401
P N +T+S + P+ + + P + + G T R A S S
Sbjct: 644 -CPKKTN-----TTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSE 697
Query: 1402 AVTDSLVAHPTVAMFTGNMLTINSYDSPPKLSAESLDKNSGPRNRADNSGKPQQPPGGFA 1461
+DS +A+ G ++ + S P + G PG
Sbjct: 698 E-SDSEEEKTGLAVTVGQAKSVGK--------GLQVKAASVPVKGSLGQGTAPVLPGKTG 748
Query: 1462 PAAINRSIPCKVIVDHSTTLTSSLSLTVSVESSEASLDLQGRPVRTEASVQPVACPQVSV 1521
P +V + SS + S E++ + ++ +T+A P A S
Sbjct: 749 PTVT------QVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSA 802
Query: 1522 ---ISRPEPVANEGIDHSSTFIAASAAKQDSKTLPATCTSLRELPLVPDKLNEPTAPSHN 1578
IS P V AA+ AKQ S P K+ P N
Sbjct: 803 KGTISAPGKVVT----------AAAQAKQRS----------------PSKVKPPVRNPQN 836
Query: 1579 FAEQARGPAPFKS 1591
ARGPA S
Sbjct: 837 STVLARGPASVPS 849
Score = 38.1 bits (87), Expect = 0.098
Identities = 196/1082 (18%), Positives = 363/1082 (33%), Gaps = 175/1082 (16%)
Query: 496 EDNLESCVMMNDV--LETLPHIEVKIE-GKSESPQEEMTVVIDQLEVCDSLIPSTSSMTH 552
E + + C + V L+ H + E G+ +E+ + + V D + S SS
Sbjct: 32 EQSGQKCFLAQPVTLLDIYTHWQQTSELGRKRKAEEDAALQAKKTRVSDPISTSESS--- 88
Query: 553 VSDTEHKESETAVETSTPKIK-TGSSSLEGQFPNEGIAIDMELQSDPEEQLSENACISET 611
E +E+E +TP++ T SS L P+ S E+ +E +T
Sbjct: 89 ---EEEEEAEAETAKATPRLASTNSSVLGADLPS----------SMKEKAKAETEKAGKT 135
Query: 612 SFSSESPEGACTSLPSPGGETQSTSEESCTPASLETTFCSEVSSTENTDKY--------- 662
S P T G++ S E S TT SE + +
Sbjct: 136 GNSMPHPATGKTVANLLSGKSPRKSAE----PSANTTLVSETEEEGSVPAFGAAAKPGMV 191
Query: 663 --NQRNSTDENFHASLMSEISPISTSPEISEASLMSNLPLTSE-----ASPVSN------ 709
Q +S+ E+ +S S+ + + P + A + ++ T E A+P
Sbjct: 192 SAGQADSSSEDTSSS--SDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVT 249
Query: 710 -------LPLTSETSPMSDLPLTSETSSVS---------SMLLTSETTF-VSSLPLPSET 752
LP + +SE S S S + SE V + P++
Sbjct: 250 PQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKG 309
Query: 753 SPISNSS----------INERMAHQQRKSPSVSEEPLSPQKDESSATAKPLGENLTSQQK 802
+P ++ ++ A + + S E S ++E+ A L + +
Sbjct: 310 TPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTS 369
Query: 803 NLSNTPEPIIMSSSSIAPEAFPSE--------DLHNKTLSQQTCKSHVDTEKPYPASIPE 854
+ P S A A P + + Q+ D+E+ PA
Sbjct: 370 QVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKP 429
Query: 855 LASTEMIKVKNHSVLQRTEKKVLPSP--------LELSVFSEGTDNKGNELPSAKLQDKQ 906
++ + + K P+P ++ V + D++ + S D++
Sbjct: 430 SGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESD--SDRE 487
Query: 907 YISSVDKAPFSEGSRNKTHKQGSTQSRLETSHTSKSSEPSKSPDGIRNESRDSEISKRKT 966
+++++ A ++ K ST + K + P P + + +++ K
Sbjct: 488 ALAAMNAAQVKPLGKSPQVKPAST---MGMGPLGKGAGP-VPPGKVGPATPSAQVGK--- 540
Query: 967 AEQHSFGICKEKRARIEDDQSTRNISSSSPPEKEQP----PREEPRVPPLKIQLSKIGPP 1022
E+ S E + D S + ++ P +E+ + +P P K K GP
Sbjct: 541 WEEDS-----ESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPV 595
Query: 1023 FI-IKSQ-PVSKPESRASTSTSVSGGRNTGARTLADIK------------------ARAQ 1062
+ +K++ P+ ES +S S A T A K A A+
Sbjct: 596 AVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAK 655
Query: 1063 QA------RAQREAAAAAAVAAAASIVSGAMGSPGEGGKTRTLAHIKEQT--------KA 1108
A +A R+A A + A ++ V+G P E + + +E+ +A
Sbjct: 656 VAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQA 715
Query: 1109 KLFAKH---QARAHLFQTSKETRLPPPLSSKEGPPNLEVSSTPETKMEGSTGVIIVNPNC 1165
K K +A + + S P L K GP +V + + E S
Sbjct: 716 KSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAA 775
Query: 1166 RSPSNKSAHLRETTTVLQQSLNPSKLPETATDLSVHSSDENIPVSHLSE-----KIVSST 1220
SP+ +++T Q NP+ + ++ + + + + ++ K+
Sbjct: 776 ASPAQVKTSVKKT----QAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPV 831
Query: 1221 SSENSSVPMLFNKNSVPVSVCSTAISGAIKEHPFVSSVDKSSVLMSVDSANTTISACNIS 1280
+ +S + SVP + A + + P S S + A T
Sbjct: 832 RNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSG 891
Query: 1281 MLKTIQGTDTPCIAIIPKCIESTPISATTEGSSISSSMDDKQLLISSSSASNLVSTQYTS 1340
I+ P K TP T ++ + DD SSS S+
Sbjct: 892 KTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSG---SSSEESD-------- 940
Query: 1341 VPTPSIGNNLPNLSTSSVLIPPMGI--NNRFPSEKIAIPGSEEQATVSMGTTVRAALSCS 1398
S G ++++ V+ PP+ NR P+ A P + A+ + + S
Sbjct: 941 ----SDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARS 996
Query: 1399 DSVAVTDSLVAHPTVAMFTG---NMLTINSYDSPPKLSAESLDKNSGPRNRADNSGKPQQ 1455
S D V T + G N++T+ + A +S + + GK Q+
Sbjct: 997 SSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQE 1056
Query: 1456 PP 1457
P
Sbjct: 1057 GP 1058
Score = 32.3 bits (72), Expect = 5.4
Identities = 42/198 (21%), Positives = 79/198 (39%), Gaps = 20/198 (10%)
Query: 38 QKEGLKETSGTSP-----LACLNAMLHTNTRIGDGTFFKIPGKSG-----LYALKKEESS 87
+K GL T G + L A + +G GT +PGK+G + A K+E+S
Sbjct: 704 EKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSE 763
Query: 88 CPADGTLDLVCESELDGTDMAEANAHGEENGVCSKQVTDEASSTRDSSLTNTAVQSKLVS 147
E E D + A + A + + ++ + A++ S+ + K+V+
Sbjct: 764 SS---------EEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVT 814
Query: 148 SFQQHTKKALKQALRQQQKRRNGVSMMVNK-TVPRVVLTPLKVSDEQSDSPSGSESKNGE 206
+ Q +++ + + +N + +VP V + Q+ S S E
Sbjct: 815 AAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEE 874
Query: 207 ADSSDKEMKHGQKSPTGK 224
+DS ++ Q P+GK
Sbjct: 875 SDSEEEAETLAQVKPSGK 892
>gi|167736355 mucin 4 isoform a [Homo sapiens]
Length = 5284
Score = 79.7 bits (195), Expect = 3e-14
Identities = 313/1533 (20%), Positives = 526/1533 (34%), Gaps = 206/1533 (13%)
Query: 373 TTGPNNAGAQSSSSCGTSGLPVSAQTALAEQQPKSMKSPASPEPGFCATLCPMVEIPPKD 432
+TG A + S+ +S S Q A Q KS + TL M+
Sbjct: 46 STGSTTATLEGQSTAASSR--TSNQDISASSQNHQTKSTETTSKAQTDTLTQMMT----- 98
Query: 433 IMAELESEDILIPEESVIQEEIAEEVETSICECQDENHKTIPEFSEEAESLTNSHEEP-- 490
S + E+ +E+ +S+ KTI + +L N+ E
Sbjct: 99 -STLFSSPSVHNVMETAPPDEMTTSFPSSVTNTLMMTSKTITMTTSTDSTLGNTEETSTA 157
Query: 491 --QIAPPEDNLESCVMMNDVLETLPHIEVKIEGKSESPQEEMT--VVIDQLEVCDSLIPS 546
+ + P + S + I+ S S Q T + +L
Sbjct: 158 GTESSTPVTSAVSITAGQEGQSRTTSWRTSIQDTSASSQNHWTRSTQTTRESQTSTLTHR 217
Query: 547 TSSMTHVSDTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMELQSDPEEQLSENA 606
T+S S + H + T + ++P +T +SSL ++ SE
Sbjct: 218 TTSTPSFSPSVHNVTGTVSQKTSPSGETATSSLCSV-------------TNTSMMTSEKI 264
Query: 607 CISETSFSSESPEGACTSLPSPGGETQSTSE-------ESCTPASLETTFCSEVSSTENT 659
++ ++ S+ G +S+P G TS E +PA+ T ST++T
Sbjct: 265 TVTTSTGSTLGNPGETSSVPVTGSLMPVTSAALVTFDPEGQSPATFSRT------STQDT 318
Query: 660 DKYNQRNSTDENFHASLMSEISPISTSPEISEASLMSNLPLTSEASPVSNLPLTSETSPM 719
+++ + T ++ + +S+I+ ++T ++ ++++S+ + + VS S +
Sbjct: 319 TAFSKNHQT-QSVETTRVSQINTLNTLTPVTTSTVLSSPSGFNPSGTVSQETFPSGETTT 377
Query: 720 SDLPLTSETSSVSSMLLTSETTFVSSLPLPSETSPISNSSINERMAHQQRKSPSVSEEPL 779
S S T V+S + T+ S+L ETS + +I+ A + S + L
Sbjct: 378 SSPSSVSNTFLVTSKVFRMPTSRDSTLGNTEETSLSVSGTIS---AITSKVSTIWWSDTL 434
Query: 780 SPQKDESSATAKPLGENLTSQQKNLSNTPEPIIMSSSS--IAPEAFPSEDLHNKTL--SQ 835
S SS K T Q + T P SS S ++ E F LH T S
Sbjct: 435 STALSPSSLPPKISTAFHTQQSEGAETTGRPHERSSFSPGVSQEIFT---LHETTTWPSS 491
Query: 836 QTCKSHVDTEKPYPASIPELASTEMIKVKNHSVLQRTEKKVLPSPLELSVFSEGTDNKGN 895
+ K H + S A+T ++ + T +V P ++S E
Sbjct: 492 FSSKGHTTWSQTELPSTSTGAATRLVTGNPSTGTAGTIPRV---PSKVSAIGE------- 541
Query: 896 ELPSAKLQDKQYISSVDKAPFSEGSRNKTHKQGSTQSRLETSHT-------SKSSEPSKS 948
P + +++ K + T + G+T L +S + ++ PS S
Sbjct: 542 --PGEPTTYSSHSTTLPKTTGAGAQTQWTQETGTTGEALLSSPSYSVTQMIKTATSPSSS 599
Query: 949 PDGIRNESRD---------SEISKRKTAEQHSFGICKEKRARI----EDDQSTRNISSSS 995
P R+ S+ S I T+ Q S + + + ++ Q+TR++S +
Sbjct: 600 PMLDRHTSQQITTAPSTNHSTIHSTSTSPQESPAVSQRGHTQAPQTTQESQTTRSVSPMT 659
Query: 996 PPEKEQPPREEPRVPPLKIQLSKIGPPFIIKSQPVSKPESRASTSTS---VSGGRNTGAR 1052
+ P S P I+ P P A+T+ + G T A
Sbjct: 660 DTKTVTTPGSS-------FTASGHSPSEIV---PQDAPTISAATTFAPAPTGDGHTTQAP 709
Query: 1053 TLA-DIKARAQQARAQREAAAAAAVAAAASIVSGAMGSPG--EGGKTRTLAHIKEQTKAK 1109
T A + A + + A ++ + + +PG EG T A T A
Sbjct: 710 TTALQAAPSSHDATLGPSGGTSLSKTGALTLANSVVSTPGGPEGQWTSASASTSPDTAAA 769
Query: 1110 LFAKHQARAHLFQTSKETRLPPPLSS-----KEGPPNLEVSSTPETKMEGSTGVIIVNPN 1164
+ HQA + + S +T+ P SS G S T GS G+
Sbjct: 770 MTHTHQAEST--EASGQTQTSEPASSGSRTTSAGTATPSSSGASGTTPSGSEGISTSGET 827
Query: 1165 CRSPSNKS--AHLRETTTVLQQSLNPSKLPETATDLSVHSSDENIPVSHLSEKIVSSTSS 1222
R SN S +H ++TT L LS +S IPVS T
Sbjct: 828 TRFSSNPSRDSHTTQSTTEL---------------LSASASHGAIPVS---------TGM 863
Query: 1223 ENSSVPMLFNKNSVPVSVCSTAISGAIKEHPFVSSVDKSSVLMSVDSANTTISACNISML 1282
+S VP F+ S + P S + +++ + T S + ++
Sbjct: 864 ASSIVPGTFHPTLSEASTAGRPTGQSSPTSPSASPQETAAISRMAQTQRTRTSRGSDTIS 923
Query: 1283 KTIQGTDT-PCIAIIPKCIESTPI-SATTEGSSISSSMDDKQLLI--------------S 1326
Q TDT + P I ST + S TE ++S S K S
Sbjct: 924 LASQATDTFSTVPPTPPSITSTGLTSPQTETHTLSPSGSGKTFTTALISNATPLPVTYAS 983
Query: 1327 SSSASNLVSTQYTSVPTPSIGNN--LPNLSTSSVLIPPMGINNRFPSEKIAIPGSEEQAT 1384
S+S + T + S G+ LP S SSV G P + +
Sbjct: 984 SASTGHTTPLHVTDASSVSTGHATPLPVTSPSSV---STGHTTPLPVTDTSSESTGHVTP 1040
Query: 1385 VSMGTTVRAALSCSDSVAVTDSLVA---HPTVAMFTGNMLTINSYDSPPKLSAESLDKNS 1441
+ + + A+ S + VTD+ A H T T ++ + ++ D+ P ++ ++
Sbjct: 1041 LPVTSFSSASTGDSTPLPVTDTSSASTGHVTPLPVT-SLSSASTGDTTPLPVTDTSSAST 1099
Query: 1442 GPRNRADNSGKPQQPPGGFAPAAINRSIPCKVIVDHSTTL----TSSLSL--TVSVESSE 1495
G + G P + + H+T+L TSS+S T + ++
Sbjct: 1100 GHATSLPVTDTSSVSTGHTTPLPVTDTSSAST--GHATSLPVTDTSSVSTGHTTPLHVTD 1157
Query: 1496 ASLDLQGR----PVRTEASVQ-------PVACPQVSVISRPEPVANEGIDHSSTFIAASA 1544
AS G+ PV + +SV PV P + P+ +ST A
Sbjct: 1158 ASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDTSSASTGHATPL 1217
Query: 1545 AKQDSKTLPATCTSLRELPLVPDKLNEPTAPSHNFAEQARGPAPFKSEADTTCSNQYNPS 1604
D A+ S +P + + H P P T S +
Sbjct: 1218 PVTD-----ASSVSTDHATSLPVTIPSAASTGHTT------PLPVTD----TSSASTGQA 1262
Query: 1605 NRICWNDDGMRSTGQ--PLVTHSGSSKQKEY---LEQSCPKAIKTEHANYLNVSELHPRN 1659
+ D STG PL S SS + L + P + T HA L V+ L +
Sbjct: 1263 TSLLVTDTSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSASTGHATPLPVTSLSSAS 1322
Query: 1660 LVTNVALPVKSELHEADKGFRMDTEDFPGPELPPPAAEGASSVQQTQNMKASTSS----P 1715
+ LPV S A G DT P + + + + T AST P
Sbjct: 1323 TGDTMPLPVTSP-SSASTG---DTTPLPVTDASSVSTGHTTPLHVTDASSASTGQATPLP 1378
Query: 1716 MEEAISLATDALKRVPGAGSSGCRLSSVEANNPLVTQLLQGNLPLEKVLPQPRLGAKLEI 1775
+ S++T +P S S+ A LVT + LP +
Sbjct: 1379 VTSLSSVSTGDTTPLPVTSPSSA--STGHATPLLVTDTSSASTGHATPLPVTDASSVSTD 1436
Query: 1776 NRLPLPLQTTSVGKTAPERNVEIPPSSPNPDGK 1808
+ LP+ S T + + +S G+
Sbjct: 1437 HATSLPVTIPSAASTGHTTPLPVTDTSSASTGQ 1469
Score = 69.7 bits (169), Expect = 3e-11
Identities = 250/1221 (20%), Positives = 420/1221 (34%), Gaps = 168/1221 (13%)
Query: 545 PSTSSMTHVSD---TEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMELQSD---- 597
PS++S H S T+ + T T P T S S P + D
Sbjct: 1734 PSSASTGHASPLLVTDASSASTGQATPLPVTDTSSVSTAHATPLPVTGLSSASTDDTTRL 1793
Query: 598 PEEQLSENACISETSFSSESPEGACTSLPSPGGETQSTSEESCTPASLETTFCSEVSSTE 657
P +S + SP A T +P T ++S + SL T S SS
Sbjct: 1794 PVTDVSSASTGQAIPLPVTSPSSASTGDTTPLPVTDASSASTGDTTSLPVTIPSSASSGH 1853
Query: 658 NTDKYNQRNSTDENFHAS--LMSEISPISTSP-------EISEASLMSNLPL-TSEASPV 707
T S+ HA+ L+++ S +ST + + AS PL ++AS V
Sbjct: 1854 TTSLPVTDASSVSTGHATSLLVTDASSVSTGDTTPLPVTDTNSASTGDTTPLHVTDASSV 1913
Query: 708 S-----NLPLTS----ETSPMSDLPLTSETSSVSSMLLTSETTFVSSLPLPSETS-PISN 757
S +LP+TS T + LP+TS +S+ S T SS+P TS P+++
Sbjct: 1914 STGHATSLPVTSLSSASTGDTTPLPVTSPSSASSGHTTPLPVTDASSVPTGHATSLPVTD 1973
Query: 758 SSINERMAHQQRKSPSVSEEPLSPQKDESSATAKPLGENLTSQQKNLSNTPEPIIMSSSS 817
+S + + P++ S+ A PL TS TP P+ SS+
Sbjct: 1974 AS--------SVSTGHATPLPVTDASSVSTGHATPLPVTDTSSVSTGQATPLPVTSLSSA 2025
Query: 818 IAPEA--FPSEDLHNKTLSQQ-----TCKSHVDT--EKPYPASIPELASTEMIKVKNHSV 868
+ P D + + Q T S V T P P + P AST H+
Sbjct: 2026 STGDTTPLPVTDTSSASTGQDTPLPVTSLSSVSTGDTTPLPVTSPSSAST------GHA- 2078
Query: 869 LQRTEKKVLPSPLELSVFSEGTDNKGNELPSAKLQDKQYISSVDKAPFSEGSRNKTHKQG 928
+PL ++ S + L D + S G H
Sbjct: 2079 ----------TPLLVTDASSVSTGHATSL-----------LVTDASSVSTGHATALHV-- 2115
Query: 929 STQSRLETSHTS--KSSEPSKSPDGIRNESRDSEISKRKTAEQHSFGICKEKRARIEDDQ 986
+ S L T T+ + PS + G ++ S T S + D
Sbjct: 2116 TDASSLSTGDTTPLPVTSPSSASTGDTTPLPVTDTSSVSTGHATSL--------PVTDTS 2167
Query: 987 STRNISSSSPPEKEQPPREEPRVPPLKIQLSKIGPPFIIKSQPVSKPESRASTSTSV--- 1043
S ++S P + PL + + PV+ P S AST ++
Sbjct: 2168 SASTGHATSLPVTDTSSASTGHATPLPVTDTSSASTGQATPLPVTSPSS-ASTGHAIPLL 2226
Query: 1044 ---SGGRNTGARTLADIKARAQQARAQREA-----AAAAAVAAAASIVSGAMGSPGEGGK 1095
+ +TG T + + + + A++ + A S+ ++ S G
Sbjct: 2227 VTDTSSASTGQATPLPVTSLSSASTGDTTPLPVTDASSVSTGHATSLPVTSLSSVSTGDT 2286
Query: 1096 TRTLAHIKEQTKAKLFAKHQARAHLFQTSKETRLPPPLSSKEGPPNLEVSSTPETKMEGS 1155
T + + + H H+ S S+ P L V+S +
Sbjct: 2287 T----PLPVTSPSSASTGHATPLHVTDASS-------ASTGHATP-LPVTSLSSASTGDT 2334
Query: 1156 TGVIIVNPNCRSPSNKS-AHLRETTTVLQQSLNPSKLPETATDLSVHSSDENIPVSHLSE 1214
T + + +P+ S + + H+ + ++V P LP T++ + +PV+ S
Sbjct: 2335 TPLPVTSPSSASTGHATPLHVTDASSVSTGDTTP--LPVTSSSSASSGHTTPLPVTDASS 2392
Query: 1215 KIVSSTSS---ENSSVPMLFNKNSVPVSVCSTAISGAIKEHPFVSSVDKSSVLMSVDSAN 1271
T+ ++S + +PV+ S+A +G P V++V +S +
Sbjct: 2393 ASTGDTTPLPVTDTSSASTGHATHLPVTGLSSASTGDTTRLP-VTNVSSASTGHATPLPV 2451
Query: 1272 TTISACNISMLKTIQGTDTPCIAIIPKCIESTPISATTEGSSISSSMDDKQLLISSSSAS 1331
T+ S+ + + GTDT ++ +TP+ T+ SS+S+ + + S SSAS
Sbjct: 2452 TSTSSASTGDTTPLPGTDTSSVS----TGHTTPL-LVTDASSVSTGDTTRLPVTSPSSAS 2506
Query: 1332 NLVST--QYTSVPTPSIGNNLP-NLSTSSVLIPPMGINNRFPSEKIAIPG--------SE 1380
+T T P+ S G+ P ++ +S L + S A G
Sbjct: 2507 TGHTTPLPVTDTPSASTGDTTPLPVTNASSLSTRHATSLHVTSPSSASTGHATSLPVTDT 2566
Query: 1381 EQATVSMGTTVRAALSCSDSVAVTDSLVAHPTVAMFTGNMLTINSYDSPPKLSAESLDKN 1440
A+ T + + S S T L T + TG + D+ + ++
Sbjct: 2567 SAASTGHATPLPVTSTSSASTGDTTPLPVTDTYSASTGQATPLPVTDTSSASTGDTTPLP 2626
Query: 1441 SGPRNRADNSGKPQQPPGGFAPAAINRSIPCKVIVDHSTTLTSSLSLTVSVESSEASLDL 1500
+ A P + + + P V S + + L V+ SS ++
Sbjct: 2627 VTDTSSASTGHATPLPVTNTSSVSTGHATPLHVTSPSSASTGHTTPLPVTDASSVSTGHA 2686
Query: 1501 QGRPVRTEASV-------QPVACPQVSVISRPEPVANEGIDHSSTFIAASAAKQDSKT-- 1551
PV +SV PV P + P+ ST A S D+ +
Sbjct: 2687 TSLPVTDASSVFTGHATSLPVTIPSSASSGHTTPLPVTDASSVSTGHATSLPVTDASSVS 2746
Query: 1552 ------LPATCTS------LRELPLVP-------DKLNEPTAPSHNFAEQARGPAPFKSE 1592
LP T S LPL D P + + + P P S
Sbjct: 2747 TGHATPLPVTDASSVSTGHATPLPLTSLSSVSTGDTTPLPVTDTSSASTGQATPLPVTSL 2806
Query: 1593 ADTTCSNQYNPSNRICWNDDGMRSTGQ----PLV-THSGSSKQKEYLEQSCPKAIKTEHA 1647
+ + + + + D STG P+ T S S+ L + + T HA
Sbjct: 2807 SSVSTGD----TTPLPVTDTSSASTGHATSLPVTDTSSASTGHATPLPDTDTSSASTGHA 2862
Query: 1648 NYLNVSELHPRNLVTNVALPV 1668
L V++ ++ +LPV
Sbjct: 2863 TLLPVTDTSSASIGHATSLPV 2883
Score = 67.0 bits (162), Expect = 2e-10
Identities = 255/1260 (20%), Positives = 433/1260 (34%), Gaps = 152/1260 (12%)
Query: 522 KSESPQEEMTVVIDQLEVCDSLIPSTSSMTHVSDTEHKESETAVETSTPKIKTGSSSLEG 581
K+ Q T + Q+ ++L P T+S S + S T + + P +T +SS
Sbjct: 323 KNHQTQSVETTRVSQINTLNTLTPVTTSTVLSSPSGFNPSGTVSQETFPSGETTTSSPSS 382
Query: 582 QFPNEGIAIDMELQSDPEEQLSENACISETSFSSESPEGACTSLPSP--GGETQSTS-EE 638
+ + ++ P + S ETS S A TS S +T ST+
Sbjct: 383 V--SNTFLVTSKVFRMPTSRDSTLGNTEETSLSVSGTISAITSKVSTIWWSDTLSTALSP 440
Query: 639 SCTPASLETTFCSEVSS-TENTDKYNQRNSTDENFHASLMS----EISPISTSPEISEAS 693
S P + T F ++ S E T + ++R+S + + P S S +
Sbjct: 441 SSLPPKISTAFHTQQSEGAETTGRPHERSSFSPGVSQEIFTLHETTTWPSSFSSKGHTTW 500
Query: 694 LMSNLPLTSEASPVSNLPLTSETSPMSDLPLTSETSSVSSMLLTSETTFVSS--LPLPSE 751
+ LP TS + + T +P S VS++ E T SS LP
Sbjct: 501 SQTELPSTSTGAATRLVTGNPSTGTAGTIPRVP--SKVSAIGEPGEPTTYSSHSTTLPKT 558
Query: 752 TSPISNSSINERMAHQQR---KSPSVSEEPLSPQKDESSATAKPLGENLTSQQKNLSNTP 808
T + + + SPS S + K +S ++ P+ + TSQQ + +
Sbjct: 559 TGAGAQTQWTQETGTTGEALLSSPSYSVTQMI--KTATSPSSSPMLDRHTSQQITTAPST 616
Query: 809 EPIIMSSSSIAPEAFPSEDLHNKTLSQQTCKSHVDTEKPYPASIPELAST--EMIKVKNH 866
+ S+S +P+ P+ T + QT + T P + + +T H
Sbjct: 617 NHSTIHSTSTSPQESPAVSQRGHTQAPQTTQESQTTRSVSPMTDTKTVTTPGSSFTASGH 676
Query: 867 SVLQRTEKKVLPSPLELSVFSEGTDNKGN--ELPSAKLQ--------------------- 903
S + + P+ + F+ G+ + P+ LQ
Sbjct: 677 SPSEIVPQDA-PTISAATTFAPAPTGDGHTTQAPTTALQAAPSSHDATLGPSGGTSLSKT 735
Query: 904 ----------------DKQYIS-SVDKAPFSEGSRNKTHKQGSTQSRLETSHTSKSSEPS 946
+ Q+ S S +P + + TH+ ST++ +T + +S S
Sbjct: 736 GALTLANSVVSTPGGPEGQWTSASASTSPDTAAAMTHTHQAESTEASGQTQTSEPASSGS 795
Query: 947 KSPDGIRNESRDSEISKRKTAEQHSFGICKE-KRARIEDDQSTRNISSSSPPEKEQPPRE 1005
++ + S T S GI + R + S + ++ S E
Sbjct: 796 RTTSA--GTATPSSSGASGTTPSGSEGISTSGETTRFSSNPSRDSHTTQSTTELLSASAS 853
Query: 1006 EPRVPPLKIQLSKIGP----PFIIKSQPVSKPESRASTSTSVSGGRNTGARTLADIKARA 1061
+P S I P P + ++ +P ++S ++ + + T A + A+
Sbjct: 854 HGAIPVSTGMASSIVPGTFHPTLSEASTAGRPTGQSSPTSPSASPQETAAISRM---AQT 910
Query: 1062 QQARAQREAAAAAAVAAAA-----------SIVSGAMGSP---------GEGGKTRTLAH 1101
Q+ R R + + + A SI S + SP GKT T A
Sbjct: 911 QRTRTSRGSDTISLASQATDTFSTVPPTPPSITSTGLTSPQTETHTLSPSGSGKTFTTAL 970
Query: 1102 IKEQTKAKL-FAKHQARAHLFQTSKETRLPPPLSSKEGPPNLEVSSTPETKMEGSTGVII 1160
I T + +A + H T +S+ P L V+S P + G T +
Sbjct: 971 ISNATPLPVTYASSASTGHT--TPLHVTDASSVSTGHATP-LPVTS-PSSVSTGHTTPLP 1026
Query: 1161 VNPNCRSPSNKSAHLRETTTVLQQSLNPSKLPETATDLSVHSSDENIPVSHLSEKIVSST 1220
V + L T+ + + + LP T T + +PV+ LS T
Sbjct: 1027 VTDTSSESTGHVTPLPVTSFSSASTGDSTPLPVTDTSSASTGHVTPLPVTSLSSASTGDT 1086
Query: 1221 SS---ENSSVPMLFNKNSVPVSVCSTAISGAIKEHPFVSSVDKSSV---------LMSVD 1268
+ ++S + S+PV+ S+ +G P + S+ SV
Sbjct: 1087 TPLPVTDTSSASTGHATSLPVTDTSSVSTGHTTPLPVTDTSSASTGHATSLPVTDTSSVS 1146
Query: 1269 SANTT-ISACNISMLKTIQGTDTPCIAIIPKCIESTPISATTEGSSISSSMDDKQLLISS 1327
+ +TT + + S T Q T P ++ T T SS S+ L+ +
Sbjct: 1147 TGHTTPLHVTDASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDT 1206
Query: 1328 SSASNLVSTQYTSVPTPSIGNNLPNLSTSSVLIPPMGINNRFPSEKIAIPGSEEQATVSM 1387
SSAS T TP + ++ST P+ I + + + ++ S
Sbjct: 1207 SSAS-------TGHATPLPVTDASSVSTDHATSLPVTIPSAASTGHTTPLPVTDTSSAST 1259
Query: 1388 GTTVRAALSCSDSVAVTDS--LVAHPTVAMFTGNM--LTINSYDSPPKLSAESLDKNS-G 1442
G ++ + SV+ D+ L T + TG++ L + S S A L S
Sbjct: 1260 GQATSLLVTDTSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSASTGHATPLPVTSLS 1319
Query: 1443 PRNRADNSGKPQQPPGGFAPAAINRSIPCKVIVDHSTTLTSSLSLTVSVESSEASLDLQG 1502
+ D P P A+ + P V S + + L V+ SS ++
Sbjct: 1320 SASTGDTMPLPVTSPSS---ASTGDTTPLPVTDASSVSTGHTTPLHVTDASSASTGQATP 1376
Query: 1503 RPVRTEASVQ-------PVACPQVSVISRPEPVANEGIDHSSTFIAASAAKQDSKTLPAT 1555
PV + +SV PV P + P+ +ST A D A+
Sbjct: 1377 LPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDTSSASTGHATPLPVTD-----AS 1431
Query: 1556 CTSLRELPLVPDKLNEPTAPSHNFAEQARGPAPFKSEADTTCSNQYNPSNRICWNDDGMR 1615
S +P + + H P P T S + + D
Sbjct: 1432 SVSTDHATSLPVTIPSAASTGHTT------PLPVTD----TSSASTGQATSLLVTDTSSV 1481
Query: 1616 STGQ--PLVTHSGSSKQKEY---LEQSCPKAIKTEHANYLNVSELHPRNLVTNVALPVKS 1670
STG PL S SS + L + P + T HA L V+ L + + LPV S
Sbjct: 1482 STGDTTPLPVTSTSSASTGHVTPLHVTSPSSASTGHATPLPVTSLSSASTGDTMPLPVTS 1541
Score = 62.4 bits (150), Expect = 5e-09
Identities = 279/1348 (20%), Positives = 465/1348 (34%), Gaps = 175/1348 (12%)
Query: 537 LEVCDSLIPSTSSMTHVSDTEHKESETAVETSTPKIKTGSSSLEGQFP----NEGIAIDM 592
L V D+ ST T + T+ + T TS P T S S P + A
Sbjct: 1105 LPVTDTSSVSTGHTTPLPVTDTSSASTGHATSLPVTDTSSVSTGHTTPLHVTDASSASTG 1164
Query: 593 ELQSDPEEQLSENACISETSFSSESPEGACTSLPSPGGETQSTSEESCTPASLETTFCSE 652
+ P LS + T SP A T +P T ++S + L T S
Sbjct: 1165 QATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDTSSASTGHATPLPVTDASS 1224
Query: 653 VSSTENTDKYNQRNSTDENFHASLM--SEISPISTSPEISEASLMSNLPLTSEASPVSNL 710
VS+ T S H + + ++ S ST S ++ T + +P L
Sbjct: 1225 VSTDHATSLPVTIPSAASTGHTTPLPVTDTSSASTGQATSLLVTDTSSVSTGDTTP---L 1281
Query: 711 PLTSETSP----MSDLPLTSETSSVSSMLLTSETTFVSS------LPLPSETSPISNSSI 760
P+TS +S ++ L +TS +S+ + T +SS +PLP TSP S++S
Sbjct: 1282 PVTSTSSASTGHVTPLHVTSPSSASTGHATPLPVTSLSSASTGDTMPLPV-TSP-SSAST 1339
Query: 761 NERMAHQQRKSPSVSEEPLSPQK--DESSAT---AKPLGENLTSQQKNLSNTPEPIIMSS 815
+ + SVS +P D SSA+ A PL S TP P+ S
Sbjct: 1340 GDTTPLPVTDASSVSTGHTTPLHVTDASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPS 1399
Query: 816 SSIAPEAFP-------SEDLHNKTLSQQTCKSHVDTEKP--YPASIPELASTEMIKVKNH 866
S+ A P S + T T S V T+ P +IP AST H
Sbjct: 1400 SASTGHATPLLVTDTSSASTGHATPLPVTDASSVSTDHATSLPVTIPSAAST------GH 1453
Query: 867 SVLQRTEKKVLPSPLELSVFSEGTDNKGNELPSAKLQDKQYISSVDKAPFSEGSRNKTHK 926
+ +PL ++ S + + L + D +S+ D P S
Sbjct: 1454 T-----------TPLPVTDTSSASTGQATSL---LVTDTSSVSTGDTTPLPVTST----- 1494
Query: 927 QGSTQSRLETSHTSKS--SEPSKSPDGIRNESRDSEISKRKTAEQHSFGICKEKRARIED 984
S T H + + PS + G + +S T + + A D
Sbjct: 1495 -----SSASTGHVTPLHVTSPSSASTGHATPLPVTSLSSASTGDTMPLPVTSPSSASTGD 1549
Query: 985 -------DQSTRNISSSSP-PEKEQPPREEPRVPPLKIQLSKIGPPFIIKSQPVSKPESR 1036
D S+ + ++P P PL + + PV+ P S
Sbjct: 1550 TTPLPVTDASSVSTGHTTPLPVTSPSSASTGHTTPLPVTDTSSASKGDTTPLPVTSPSSA 1609
Query: 1037 ASTSTSVSGGRNTGARTLAD---IKARAQQARAQREAAAAAAVAAAASIVSGAMGSPGEG 1093
++ T+ +T + + D + + + A + +++ A P
Sbjct: 1610 STGHTTPLPVTDTSSASTGDTTPLPVTNASSLSTGHATPLHVTSPSSASTGHATPLPVTS 1669
Query: 1094 GKTRTLAHIKEQTKAKLFAKHQARAHLFQTSKETRLP----PPLSSKEGPPNLEVSSTPE 1149
+ + H L + T TRLP S+ + P L V+S
Sbjct: 1670 TSSASTGHATPLPVTGLSSA--------TTDDTTRLPVTDVSSASTGQATP-LPVTSLSS 1720
Query: 1150 TKMEGSTGVIIVNPNCRSPSNKSAHL-RETTTVLQQSLNPSKLPETATDLSVHSSDENIP 1208
+T + + +P+ S + S L + ++ P + +T++ + H++ +P
Sbjct: 1721 VSTGDTTPLPVTSPSSASTGHASPLLVTDASSASTGQATPLPVTDTSSVSTAHATP--LP 1778
Query: 1209 VSHLSEKIVSSTSSENSSVPMLFNKNSVPVSVCSTAISGAIKEHPFVSSVDKSSVLMSVD 1268
V+ LS T+ +PV+ S+A +G P S S+
Sbjct: 1779 VTGLSSASTDDTTR-------------LPVTDVSSASTGQAIPLPVTSPSSAST------ 1819
Query: 1269 SANTTISACNISMLKTIQGTDTPCIAIIPKCIES--TPISATTEGSSISSSMDDKQLLIS 1326
T + + S T T P IP S T T+ SS+S+ L+
Sbjct: 1820 GDTTPLPVTDASSASTGDTTSLP--VTIPSSASSGHTTSLPVTDASSVSTGHATSLLVTD 1877
Query: 1327 SSSASNLVSTQY--TSVPTPSIGNNLP-------NLSTS-SVLIPPMGINNRFPSEKIAI 1376
+SS S +T T + S G+ P ++ST + +P +++ + +
Sbjct: 1878 ASSVSTGDTTPLPVTDTNSASTGDTTPLHVTDASSVSTGHATSLPVTSLSSASTGDTTPL 1937
Query: 1377 PGSEEQATVSMGTTVRAALSCSDSVAV--TDSLVAHPTVAMFTGNMLTINSYDSPPKLSA 1434
P + ++ S G T ++ + SV SL ++ TG+ + D+ +
Sbjct: 1938 PVTSP-SSASSGHTTPLPVTDASSVPTGHATSLPVTDASSVSTGHATPLPVTDASSVSTG 1996
Query: 1435 ESLDKNSGPRNRADNSGKPQQPPGGFAPAAINRSIPCKVIVDHSTTLTSSLSLTVSVESS 1494
+ + P + A+ + P V S + L V+ SS
Sbjct: 1997 HATPLPVTDTSSVSTGQATPLPVTSLSSASTGDTTPLPVTDTSSASTGQDTPLPVTSLSS 2056
Query: 1495 EASLDLQGRPVRTEASVQ-----PVACPQVSVISRPEPVANEGIDHSSTFI--------- 1540
++ D PV + +S P+ S +S + D SS
Sbjct: 2057 VSTGDTTPLPVTSPSSASTGHATPLLVTDASSVSTGHATSLLVTDASSVSTGHATALHVT 2116
Query: 1541 -AASAAKQDSKTLPATCTSLRELPLVPDKLNEPTAPSHNFAEQARGPAPFKSEADTTCSN 1599
A+S + D+ LP T S + P + + + G A DT+ ++
Sbjct: 2117 DASSLSTGDTTPLPVTSPSSASTG------DTTPLPVTDTSSVSTGHATSLPVTDTSSAS 2170
Query: 1600 QYNPSNRICWNDDGMRSTGQ--PLV---THSGSSKQKEYLEQSCPKAIKTEHANYLNVSE 1654
+ ++ + D STG PL T S S+ Q L + P + T HA L V++
Sbjct: 2171 TGHATS-LPVTDTSSASTGHATPLPVTDTSSASTGQATPLPVTSPSSASTGHAIPLLVTD 2229
Query: 1655 LHPRNLVTNVALPVKSELHEADKGFRMDTEDFPGPELPPPAAEGASSVQQTQNMKASTSS 1714
+ LPV S L A G DT P ASSV +TS
Sbjct: 2230 TSSASTGQATPLPVTS-LSSASTG---DTTPLP--------VTDASSVSTGH----ATSL 2273
Query: 1715 PMEEAISLATDALKRVPGAGSSGCRLSSVEANNPLVTQLLQGNLPLEKVLPQPRLGAKLE 1774
P+ S++T +P S S+ A VT + LP L +
Sbjct: 2274 PVTSLSSVSTGDTTPLPVTSPSSA--STGHATPLHVTDASSASTGHATPLPVTSLSSAST 2331
Query: 1775 INRLPLPLQTTSVGKTAPERNVEIPPSS 1802
+ PLP+ + S T + + +S
Sbjct: 2332 GDTTPLPVTSPSSASTGHATPLHVTDAS 2359
Score = 58.5 bits (140), Expect = 7e-08
Identities = 281/1365 (20%), Positives = 471/1365 (34%), Gaps = 185/1365 (13%)
Query: 537 LEVCDSLIPSTSSMTHVSDTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMELQS 596
L V D+ ST T + T+ + T T P TG SS + G + + +
Sbjct: 2385 LPVTDASSASTGDTTPLPVTDTSSASTGHATHLPV--TGLSSA-----STGDTTRLPVTN 2437
Query: 597 DPEEQLSENACISETSFSSESPEGACTSLPSPGGETQSTSEESCTPASLETTFCSEVSST 656
+ TS SS S + P PG +T S S TP L T S VS+
Sbjct: 2438 VSSASTGHATPLPVTSTSSASTGD---TTPLPGTDTSSVSTGHTTP--LLVTDASSVSTG 2492
Query: 657 ENTDKYNQRNSTDENFHASLMSEISPISTSPEISEASLMSNLPLTSEASPVSNLPLTS-- 714
+ T S+ H + + P++ +P S + LP+T+ AS +S TS
Sbjct: 2493 DTTRLPVTSPSSASTGHTTPL----PVTDTPSASTGDT-TPLPVTN-ASSLSTRHATSLH 2546
Query: 715 ETSPMS-------DLPLTSETSSVSS-------MLLTSETTFVSSLPLPSETSPISNSSI 760
TSP S LP+T +TS+ S+ + TS + + PLP + +++
Sbjct: 2547 VTSPSSASTGHATSLPVT-DTSAASTGHATPLPVTSTSSASTGDTTPLPVTDTYSASTGQ 2605
Query: 761 NERMAHQQRKSPSVSEEPLSPQKDESSAT---AKPLGENLTSQQKNLSNTPEPIIMSSSS 817
+ S S + P D SSA+ A PL TS TP + SS+
Sbjct: 2606 ATPLPVTDTSSASTGDTTPLPVTDTSSASTGHATPLPVTNTSSVSTGHATPLHVTSPSSA 2665
Query: 818 IAPEA--FPSEDLHNKTLSQQTCKSHVDTEKPY-------PASIPELAS---TEMIKVKN 865
P D + + T D + P +IP AS T + V +
Sbjct: 2666 STGHTTPLPVTDASSVSTGHATSLPVTDASSVFTGHATSLPVTIPSSASSGHTTPLPVTD 2725
Query: 866 HSVLQRTEKKVLPSPLELSVFSEGTDNKGNELPSAKLQDKQYISSVDKAPFSEGSRNKTH 925
S + LP V + + G+ P + D +S+ P S +
Sbjct: 2726 ASSVSTGHATSLP------VTDASSVSTGHATP-LPVTDASSVSTGHATPLPLTSLSSVS 2778
Query: 926 KQGSTQSRLETSHTSKSSEPSKSPDGIRNESRDSEISKRKTAEQHSFGICKEKRARIEDD 985
+T L + TS +S +P + + +S T + + A
Sbjct: 2779 TGDTTP--LPVTDTSSASTGQATPLPV------TSLSSVSTGDTTPLPVTDTSSASTGHA 2830
Query: 986 QSTRNISSSSPPEKEQPPREEPRVPPLKIQLSKIGPPFIIKSQPVSKPESRASTSTS-VS 1044
S +SS P + + + P S + S T TS +S
Sbjct: 2831 TSLPVTDTSSASTGHATPLPDTDTSSASTGHATLLPVTDTSSASIGHATSLPVTDTSSIS 2890
Query: 1045 GGRNTGARTLADIKARAQQARAQREAAAAAAVAAAASIVSGAMGSPGEGGKTRTLAHIKE 1104
G T + A A ++A A+ + S G L
Sbjct: 2891 TGHATPLHVTSPSSASTGHATPLPVTDTSSASTGHANPLHVTSPSSASTGHATPLPVTDT 2950
Query: 1105 QTKAKLFAKHQARAHLFQTSKETRLPPPLSSKEGPPNLEVSSTPETKMEGSTGVIIVNPN 1164
+ + A L S P P++S P + G T + V
Sbjct: 2951 SSASTGHATPLPVTSLSSVSTGDTTPLPVTS------------PSSASTGHTTPLPVTDT 2998
Query: 1165 CRSPSNKSAHLRETTTVLQQSLNPSKLPETATDLSVHSSDENIPVSHLSEKIVS------ 1218
+ + ++ L T+T + + + LP T T + +PV+ LS
Sbjct: 2999 SSASTGQATALPVTSTSSASTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLP 3058
Query: 1219 ----STSSENSSVPMLFNKNS---------VPVSVCSTAISGAIKEHPFVS----SVDKS 1261
S++S + P+L S +PV+ S+ +G P S S +
Sbjct: 3059 VTSPSSASTGHATPLLVTDASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHA 3118
Query: 1262 SVLMSVDSAN------TTISACNISMLKTIQGTDTPCIAIIPKCIESTPISATTEGSSIS 1315
+ L D+++ T++ + S T T P T TE SS+S
Sbjct: 3119 TSLPVTDTSSASTGDTTSLPVTDTSSAYTGDTTSLPVTDTSSSSTGDTTPLLVTETSSVS 3178
Query: 1316 SSMDDKQLLISSSSASNLVST--QYTSVPTPSIGNN--LPNLSTSSVL------IPPMGI 1365
+ L+ +SSAS +T TS + S G+ +P TSSV +P G+
Sbjct: 3179 TGHATPLLVTDASSASTGHATPLHVTSPSSASTGDTTPVPVTDTSSVSTGHATPLPVTGL 3238
Query: 1366 NNRFPSEKIAIPGSEEQATVSMGTTVRAALSCSDSVAVTDSL-----------VAHPTVA 1414
++ + +P + + ++ S G ++ + SV+ D++ H T
Sbjct: 3239 SSASTGDTTRLPVT-DISSASTGQATPLPVTNTSSVSTGDTMPLPVTSPSSASTGHATPL 3297
Query: 1415 MFTGNMLTINSYDSP-PKLSAESLD---------KNSGPRNRADNSGKPQQPPGGFAPAA 1464
T + +P P S S ++ + D + P P + A+
Sbjct: 3298 PVTSTSSASTGHATPVPVTSTSSASTGHTTPLPVTDTSSASTGDTTPLPVTSP---SSAS 3354
Query: 1465 INRSIPCKVIVDHSTTLTSSLSLTVSVESSEASLDLQGRPVRTEASVQ-----PVACPQV 1519
+ P V + S + + +L V+ SS ++ PV +SV P+ +
Sbjct: 3355 TGHTTPLHVTIPSSASTGDTSTLPVTGASSASTGHATPLPVTDTSSVSTGHATPLPVTSL 3414
Query: 1520 SVIS----RPEPVANEGIDHSSTFIAASAAKQDSKTLPAT-CTSLRELPLVPDKLNEPTA 1574
S +S P PV + A+SA+ + LP T +S+ P + + ++
Sbjct: 3415 SSVSTGDTTPLPVTD----------ASSASTGQATPLPVTSLSSVSTGDTTPLLVTDASS 3464
Query: 1575 PSHNFAEQARGPAPFKSEADTTCSNQYNPSNRICWNDDGMRSTGQ----PLVTHSG-SSK 1629
S A P P T S + R+ D STGQ P+ + S S+
Sbjct: 3465 VSTGHAT----PLP----VTDTSSASTGDTTRLPVTDTSSASTGQATPLPVTSLSSVSTG 3516
Query: 1630 QKEYLEQSCPKAIKTEHANYLNVSELHPRNLVTNVALPVKSELHEADKGFRMDTEDFPGP 1689
L + ++ T HA L V++ + LPV ++ A G + P P
Sbjct: 3517 DTTPLLVTDASSVSTGHATPLPVTDTSSASTGDTTRLPV-TDTSSASTG-----QATPLP 3570
Query: 1690 -ELPPPAAEGASS---VQQTQNMKASTSSPMEEAISLATDALKRVPGAGSSGCRLSSVEA 1745
+P ++ G ++ V T ++ +P+ + P +S S+ A
Sbjct: 3571 VTIPSSSSSGHTTPLPVTSTSSVSTGHVTPLHVTSPSSASTGHVTPLPVTSTSSASTGHA 3630
Query: 1746 NNPLVTQLLQGNLPLEKVLPQPRLGAKLEINRLPLPLQTTSVGKT 1790
LVT + LP + + PLP+ TS T
Sbjct: 3631 TPLLVTDASSVSTGHATPLPVTDASSASTGDTTPLPVTDTSSAST 3675
Score = 57.4 bits (137), Expect = 2e-07
Identities = 261/1304 (20%), Positives = 442/1304 (33%), Gaps = 152/1304 (11%)
Query: 525 SPQEEMTVVIDQLEVCDSLIPSTSSMTHVSDTEHKESETAVETSTPKIKTGSSSLEGQFP 584
SP + L V D+ T T + T+ S + +TP T +SS+
Sbjct: 1941 SPSSASSGHTTPLPVTDASSVPTGHATSLPVTD--ASSVSTGHATPLPVTDASSV----- 1993
Query: 585 NEGIAIDMELQSDPEEQLSENACISETSFSSESPEGACTSLPSPGGETQSTSEESCTPAS 644
+ G A + + + + TS SS S G T LP + ST +++ P
Sbjct: 1994 STGHATPLPVTDTSSVSTGQATPLPVTSLSSAST-GDTTPLPVTDTSSASTGQDTPLPV- 2051
Query: 645 LETTFCSEVSSTENTDKYNQRNSTDENFHAS--LMSEISPIST----SPEISEASLMSNL 698
T S VS+ + T S+ HA+ L+++ S +ST S +++AS +S
Sbjct: 2052 ---TSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDASSVSTGHATSLLVTDASSVSTG 2108
Query: 699 PLTSEASPVSNLPLTSETSPMSDLPLTSETSSVSSMLLTSETTFVSSLPLP-SETSPISN 757
T+ ++ T +T+P LP+TS +S+ T +TT PLP ++TS +S
Sbjct: 2109 HATALHVTDASSLSTGDTTP---LPVTSPSSAS-----TGDTT-----PLPVTDTSSVST 2155
Query: 758 SSINERMAHQQRKSPSVSEEPLSPQKDESSAT---AKPLGENLTSQQKNLSNTPEPIIMS 814
+ S S P D SSA+ A PL TS TP P+
Sbjct: 2156 GHATS-LPVTDTSSASTGHATSLPVTDTSSASTGHATPLPVTDTSSASTGQATPLPVTSP 2214
Query: 815 SSSIAPEAFPSEDLHNKTLSQQTCKSHVDTEKPYPASIPELASTEMIKVKNHSVLQRTEK 874
SS+ A P L T + P P + AST
Sbjct: 2215 SSASTGHAIP-------LLVTDTSSASTGQATPLPVTSLSSASTGD-------------- 2253
Query: 875 KVLPSPLELSVFSEGTDNKGNELPSAKLQDKQYISSVDKAPFSEGSRNKTHKQGSTQSRL 934
+PL ++ S + LP L +S+ D P S + +T +
Sbjct: 2254 ---TTPLPVTDASSVSTGHATSLPVTSLSS---VSTGDTTPLPVTSPSSASTGHATPLHV 2307
Query: 935 ETSHTSKSSEPSKSPDGIRNESRDSEISKRKTAEQHSFGICKEKRARIEDDQSTRNISSS 994
+ ++ + + P + + + + S + D S ++
Sbjct: 2308 TDASSASTGHATPLPVTSLSSASTGDTTPLPVTSPSSASTGHATPLHVTDASSVSTGDTT 2367
Query: 995 SPPEKEQPPREEPRVPPLKIQLSKIGPPFIIKSQPVSKPESRA---STSTSVSGGRNTGA 1051
P PL + + PV+ S + +T V+G +
Sbjct: 2368 PLPVTSSSSASSGHTTPLPVTDASSASTGDTTPLPVTDTSSASTGHATHLPVTGLSSAST 2427
Query: 1052 RTLADIKARAQQARAQREAAAAAAVAAAASIVSGAMGSPGEGGKTRTLAHIKEQTKAKLF 1111
+ + + A + +++ PG + + H T L
Sbjct: 2428 GDTTRLPVTNVSSASTGHATPLPVTSTSSASTGDTTPLPGTDTSSVSTGH----TTPLLV 2483
Query: 1112 AKHQARAHLFQTSKETRLP---PPLSSKEGPPNLEVSSTPETKMEGSTGVIIVNPNCRSP 1168
A T TRLP P +S L V+ TP +T + + N + S
Sbjct: 2484 TD----ASSVSTGDTTRLPVTSPSSASTGHTTPLPVTDTPSASTGDTTPLPVTNASSLS- 2538
Query: 1169 SNKSAHLRETTTVLQQSLNPSKLPETATDLSVHSSDENIPVSHLSEKIVSST-------- 1220
+ + L T+ + + + LP T T + +PV+ S T
Sbjct: 2539 TRHATSLHVTSPSSASTGHATSLPVTDTSAASTGHATPLPVTSTSSASTGDTTPLPVTDT 2598
Query: 1221 --SSENSSVPMLFNKNS---------VPVSVCSTAISGAIKEHPFVSSVDKSS------V 1263
+S + P+ S +PV+ S+A +G P ++ S+
Sbjct: 2599 YSASTGQATPLPVTDTSSASTGDTTPLPVTDTSSASTGHATPLPVTNTSSVSTGHATPLH 2658
Query: 1264 LMSVDSAN----TTISACNISMLKTIQGTDTP---CIAIIPKCIESTPI---SATTEGSS 1313
+ S SA+ T + + S + T T P ++ S P+ S+ + G +
Sbjct: 2659 VTSPSSASTGHTTPLPVTDASSVSTGHATSLPVTDASSVFTGHATSLPVTIPSSASSGHT 2718
Query: 1314 ISSSMDDKQLLISSSSASNLVSTQYTSVPTPSIGNNLPNLSTSSVL------IPPMGINN 1367
+ D +S+ A++L T +SV T LP SSV +P +++
Sbjct: 2719 TPLPVTDAS-SVSTGHATSLPVTDASSVST-GHATPLPVTDASSVSTGHATPLPLTSLSS 2776
Query: 1368 RFPSEKIAIPGSE-EQATVSMGTTVRAALSCSDSVAVTDSLVAHPTVAMFTGNMLTINSY 1426
+ +P ++ A+ T + S S T L T + TG+ ++
Sbjct: 2777 VSTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTDTSSASTGHATSLPVT 2836
Query: 1427 DSPPKLSAESLDKNSGPRNRADNSGKPQQPPGGFAPAAINRSIPCKVIVDHSTTLTSSLS 1486
D+ + + + A P + A+I + V S + +
Sbjct: 2837 DTSSASTGHATPLPDTDTSSASTGHATLLPVTDTSSASIGHATSLPVTDTSSISTGHATP 2896
Query: 1487 LTVSVESSEASLDLQGRPVRTEASVQPVACPQVSVISRPEPVANEGIDHSSTFIAASAAK 1546
L V+ SS ++ PV +S + V S P + +SA+
Sbjct: 2897 LHVTSPSSASTGHATPLPVTDTSSASTGHANPLHVTS-PSSASTGHATPLPVTDTSSAST 2955
Query: 1547 QDSKTLPAT-CTSLRELPLVPDKLNEPTAPSHNFAEQARGPAPFKSEADT---------- 1595
+ LP T +S+ P + P++ S P S A T
Sbjct: 2956 GHATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHTTPL--PVTDTSSASTGQATALPVTS 3013
Query: 1596 TCSNQYNPSNRICWNDDGMRSTGQ----PLVTHSG-SSKQKEYLEQSCPKAIKTEHANYL 1650
T S + + D STGQ P+ + S S+ L + P + T HA L
Sbjct: 3014 TSSASTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPL 3073
Query: 1651 NVSELHPRNLVTNVALPVKSELHEADKGFRMDTEDFPGPELPPPAAEGASSVQQTQNMKA 1710
V++ + LPV S L G DT P + A+S+ T A
Sbjct: 3074 LVTDASSASTGQATPLPVTS-LSSVSTG---DTTPLPVTSPSSASTGHATSLPVTDTSSA 3129
Query: 1711 S----TSSPMEEAISLATDALKRVPGAGSSGCRLSSVEANNPLV 1750
S TS P+ + S T +P +S SS PL+
Sbjct: 3130 STGDTTSLPVTDTSSAYTGDTTSLPVTDTSS---SSTGDTTPLL 3170
Score = 57.0 bits (136), Expect = 2e-07
Identities = 186/905 (20%), Positives = 319/905 (35%), Gaps = 119/905 (13%)
Query: 525 SPQEEMTVVIDQLEVCDSLIPSTSSMTHVSDTEHKESETAVETSTPKIKTGSSSLEGQFP 584
SP T L V + ST T V T + T T P T S+S P
Sbjct: 3285 SPSSASTGHATPLPVTSTSSASTGHATPVPVTSTSSASTGHTTPLPVTDTSSASTGDTTP 3344
Query: 585 ---------NEGIAIDMELQSDPEEQLSENACISETSFSSESPEGACTSLPSPGGETQST 635
+ G + + + + + T SS S A P P +T S
Sbjct: 3345 LPVTSPSSASTGHTTPLHVTIPSSASTGDTSTLPVTGASSASTGHAT---PLPVTDTSSV 3401
Query: 636 SEESCTPASLETTFCSEVSSTENT-----DKYNQRNSTDENFHASLMSEISPISTSPE-I 689
S TP L T S VS+ + T D + + +S +S T+P +
Sbjct: 3402 STGHATP--LPVTSLSSVSTGDTTPLPVTDASSASTGQATPLPVTSLSSVSTGDTTPLLV 3459
Query: 690 SEASLMSN-----LPLTSEASP----VSNLPLT----SETSPMSDLPLTS----ETSSVS 732
++AS +S LP+T +S + LP+T + T + LP+TS T +
Sbjct: 3460 TDASSVSTGHATPLPVTDTSSASTGDTTRLPVTDTSSASTGQATPLPVTSLSSVSTGDTT 3519
Query: 733 SMLLTSETTFVSSLPLPSETSPISNSSINERMAHQQRKSPSVSEEPLSPQKDESSATAKP 792
+L+T ++ + P + S++S + + P++ S+ A P
Sbjct: 3520 PLLVTDASSVSTGHATPLPVTDTSSASTGD-----------TTRLPVTDTSSASTGQATP 3568
Query: 793 LGENLTSQQKNLSNTPEPIIMSSSSIAPEAFPSEDLHNKTLSQQTCKSHVDTEKPYPASI 852
L + S + TP P+ +SS P LH T HV P P +
Sbjct: 3569 LPVTIPSSSSSGHTTPLPVTSTSSVSTGHVTP---LH-VTSPSSASTGHVT---PLPVTS 3621
Query: 853 PELAST---EMIKVKNHSVLQRTEKKVLP------------SPLELSVFSEGTDNKGNEL 897
AST + V + S + LP +PL ++ S + + L
Sbjct: 3622 TSSASTGHATPLLVTDASSVSTGHATPLPVTDASSASTGDTTPLPVTDTSSASTGQATPL 3681
Query: 898 PSAKLQDKQYISSVDKAPF------SEGSRNKTHKQGSTQSRLETSHTSKS--SEPSKSP 949
P L +S+ D P S + + T + S + T T + PS +
Sbjct: 3682 PVTSLSS---VSTGDTTPLPVTDASSASTGHATPLPVTIPSSVSTGDTMPLPVTSPSSAS 3738
Query: 950 DGIRNESRDSEISKRKTAEQHSFGICKEKRARIEDDQSTRNISSSSPPEKEQPPREEP-R 1008
G + +S T + + A STR+ + + ++ R
Sbjct: 3739 TGHATPLPVTGLSSASTGDTTPLPVTDTSSA------STRHATPLPVTDTSSASTDDTTR 3792
Query: 1009 VPPLKIQLSKIG--PPFIIKSQPVSKPESRASTSTSVSGGRNTGARTLADIKARAQQARA 1066
+P + + G P + S + + + +TG T + +R+ +
Sbjct: 3793 LPVTDVSSASTGHATPLPVTSTSSASTGDTTPLPVTDTSSVSTGHATSLPVTSRSSASTG 3852
Query: 1067 QREAAAAAAVAAAASIVSG-AMGSPGEGGKTRTLAH---IKEQTKAKLFAKHQARAHLFQ 1122
A V +S+ +G A P + + H + + + H +
Sbjct: 3853 H---ATPLPVTDTSSVSTGHATPLPVTSTSSVSTGHATPLPVTSPSSASTGHATPVPVTS 3909
Query: 1123 TSKE-----TRLP----PPLSSKEGPPNLEVSSTPETKMEGSTGVIIVNPNCRSPSNKSA 1173
TS T LP LS+ P L V+S P + G T + V + + +
Sbjct: 3910 TSSASTGDTTPLPVTNASSLSTGHATP-LHVTS-PSSASRGDTSTLPVTDASSASTGHAT 3967
Query: 1174 HLRETTTVLQQSLNPSKLPETATDLSVHSSDENIPVSHLSEKIVSSTSSENSSVPMLFNK 1233
L T+ + + + LP T T + +PV+ LS T+ ++P +
Sbjct: 3968 PLPLTSLSSVSTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTIPSSASS 4027
Query: 1234 ---NSVPVSVCSTAISGAIKEHPFVSSVDKSSVLMSVDSANTTISACNISMLKTIQGTDT 1290
S+PV+ S+ +G P V+S +S + T S+ + + TDT
Sbjct: 4028 GHTTSLPVTDASSVSTGHGTPLP-VTSTSSASTGDTTPLPVTDTSSASTGHATPLPVTDT 4086
Query: 1291 PCIAIIPKCIESTPISATTEGSSISSSMDDKQLLISSSSASNLVSTQYTSVPTPSIGNNL 1350
+ +TP+ T+ SS+S+ + S++SAS + S + TP G
Sbjct: 4087 SSAS----TGHATPLPVTSL-SSVSTGHATPLAVSSATSASTVSSDSPLKMETP--GMTT 4139
Query: 1351 PNLST 1355
P+L T
Sbjct: 4140 PSLKT 4144
Score = 55.1 bits (131), Expect = 8e-07
Identities = 288/1380 (20%), Positives = 468/1380 (33%), Gaps = 165/1380 (11%)
Query: 561 SETAVETSTPKIKTGSSSLEGQF--------PNEGIAIDMELQSDPEEQLSENACISETS 612
S+T T + + EGQ+ P+ A+ Q++ E + SE +
Sbjct: 733 SKTGALTLANSVVSTPGGPEGQWTSASASTSPDTAAAMTHTHQAESTEASGQTQT-SEPA 791
Query: 613 FSSESPEGACTSLPSPGGETQST--SEESCTPASLETTFCSEVSSTENTDKYNQRNSTDE 670
S A T+ PS G + +T E + + T F S S +T + ST E
Sbjct: 792 SSGSRTTSAGTATPSSSGASGTTPSGSEGISTSGETTRFSSNPSRDSHTTQ-----STTE 846
Query: 671 NFHASLMSEISPISTSPEISEASLMSNLPLTSEASPVSNLPLTSETSPMSDLPLTSETSS 730
AS P+ST S + P SEAS T ++SP S ET++
Sbjct: 847 LLSASASHGAIPVSTGMASSIVPGTFH-PTLSEASTAGRP--TGQSSPTSPSASPQETAA 903
Query: 731 VSSMLLTSETTFVSSLPLPSETSPISNSSINERMAHQQRKSPSVSEEPLSPQKDESSATA 790
+S M T T S+T ++ S + + PS++ L+ + E+ T
Sbjct: 904 ISRMAQTQRTRTSRG----SDTISLA-SQATDTFSTVPPTPPSITSTGLTSPQTETH-TL 957
Query: 791 KPLGENLTSQQKNLSN-TPEPIIMSSSSIAPEAFP-------SEDLHNKTLSQQTCKSHV 842
P G T +SN TP P+ +SS+ P S + T T S V
Sbjct: 958 SPSGSGKTFTTALISNATPLPVTYASSASTGHTTPLHVTDASSVSTGHATPLPVTSPSSV 1017
Query: 843 DTEKPYPASIPELASTEMIKVKNHSVLQRTEKKVLPS-PLELSVFSEGTDNKGNELP--- 898
T P + + +S V V + S PL ++ S + LP
Sbjct: 1018 STGHTTPLPVTDTSSESTGHVTPLPVTSFSSASTGDSTPLPVTDTSSASTGHVTPLPVTS 1077
Query: 899 --SAKLQDKQYISSVDKAPFSEGSRNKTHKQGSTQSRLETSHTSKS--SEPSKSPDGIRN 954
SA D + D + S G + T + S + T HT+ ++ S + G
Sbjct: 1078 LSSASTGDTTPLPVTDTSSASTG--HATSLPVTDTSSVSTGHTTPLPVTDTSSASTGHAT 1135
Query: 955 ESRDSEISKRKTAEQHSFGICKEKRARIEDDQSTRNISSSSPPEKEQPPREEPRVPPLKI 1014
++ S T + A S SS + P P P
Sbjct: 1136 SLPVTDTSSVSTGHTTPLHVTDASSASTGQATPLPVTSLSSVSTGDTTPL--PVTSPSSA 1193
Query: 1015 QLSKIGPPFIIKSQPVSKPESR---ASTSTSVSGGRNTGAR-TLADIKARAQQARAQREA 1070
P + + S + + ++SVS T T+ +
Sbjct: 1194 STGHATPLLVTDTSSASTGHATPLPVTDASSVSTDHATSLPVTIPSAASTGHTTPLPVTD 1253
Query: 1071 AAAAAVAAAASIVSGAMGSPGEGGKTRT-LAHIKEQTKAKLFAKHQARAHLFQTSKETRL 1129
++A+ A S++ S G T + + + H T T L
Sbjct: 1254 TSSASTGQATSLLVTDTSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSASTGHATPL 1313
Query: 1130 P-PPLSSKEGPPNLEVSST-PETKMEGSTGVIIVNPNCRSPSNKSAHLRETTTVLQQSLN 1187
P LSS + + T P + G T + V + + L T +
Sbjct: 1314 PVTSLSSASTGDTMPLPVTSPSSASTGDTTPLPVTDASSVSTGHTTPLHVTDASSASTGQ 1373
Query: 1188 PSKLPETATDLSVHSSDEN-IPVS--------HLSEKIVSSTSSENS-----------SV 1227
+ LP T+ SV + D +PV+ H + +V+ TSS ++ S
Sbjct: 1374 ATPLPVTSLS-SVSTGDTTPLPVTSPSSASTGHATPLLVTDTSSASTGHATPLPVTDASS 1432
Query: 1228 PMLFNKNSVPVSVCSTAISGAIKEHPFVSSVDKS-----SVLMSVDSANTTISACNISML 1282
+ S+PV++ S A +G P + S S+L++ S+ +T + +
Sbjct: 1433 VSTDHATSLPVTIPSAASTGHTTPLPVTDTSSASTGQATSLLVTDTSSVSTGDTTPLPVT 1492
Query: 1283 KTIQ---GTDTPCIAIIPKCIES---TPISATTEGSSISSSMDDKQLLISSSSASNLVST 1336
T G TP P + TP+ T+ S+ S+ D L ++S S+++ T
Sbjct: 1493 STSSASTGHVTPLHVTSPSSASTGHATPLPVTSLSSA--STGDTMPLPVTSPSSASTGDT 1550
Query: 1337 Q---YTSVPTPSIGNNLPNLSTS--------SVLIPPMGINNRFPSEKIAIP-GSEEQAT 1384
T + S G+ P TS + +P ++ + +P S A+
Sbjct: 1551 TPLPVTDASSVSTGHTTPLPVTSPSSASTGHTTPLPVTDTSSASKGDTTPLPVTSPSSAS 1610
Query: 1385 VSMGTTVRAALSCSDSVAVTDSLVAHPTVAMFTGNM--LTINSYDSPPKLSAESLDKNSG 1442
T + + S S T L ++ TG+ L + S S A L S
Sbjct: 1611 TGHTTPLPVTDTSSASTGDTTPLPVTNASSLSTGHATPLHVTSPSSASTGHATPLPVTS- 1669
Query: 1443 PRNRADNSGKPQQPPGGFAPAAINRSIPCKVIVDHSTTLTSSLSLTVSVESSEASLDLQG 1502
+ A P G + A + + V S + + L V+ SS ++ D
Sbjct: 1670 -TSSASTGHATPLPVTGLSSATTDDTTRLPVTDVSSASTGQATPLPVTSLSSVSTGDTTP 1728
Query: 1503 RPVRTEASVQ-----PVACPQVSVISRPEPVANEGIDHSSTFIA----------ASAAKQ 1547
PV + +S P+ S S + D SS A +SA+
Sbjct: 1729 LPVTSPSSASTGHASPLLVTDASSASTGQATPLPVTDTSSVSTAHATPLPVTGLSSASTD 1788
Query: 1548 DSKTLPATCTSLREL-PLVPDKLNEPT--------------APSHNFAEQARGPAPFKSE 1592
D+ LP T S +P + P+ A S + + P S
Sbjct: 1789 DTTRLPVTDVSSASTGQAIPLPVTSPSSASTGDTTPLPVTDASSASTGDTTSLPVTIPSS 1848
Query: 1593 ADT----------TCSNQYNPSNRICWNDDGMRSTGQ--PLV---THSGSSKQKEYLEQS 1637
A + S + + D STG PL T+S S+ L +
Sbjct: 1849 ASSGHTTSLPVTDASSVSTGHATSLLVTDASSVSTGDTTPLPVTDTNSASTGDTTPLHVT 1908
Query: 1638 CPKAIKTEHANYLNVSELHPRNLVTNVALPVKSELHEADKGFRMDTEDFPGPELPPPAAE 1697
++ T HA L V+ L + LPV S A G T P +
Sbjct: 1909 DASSVSTGHATSLPVTSLSSASTGDTTPLPVTSP-SSASSG---HTTPLPVTDASSVPTG 1964
Query: 1698 GASSVQQTQNMKASTSS----PMEEAISLATDALKRVPGAGSSGCRLSSVEANNPLVTQL 1753
A+S+ T ST P+ +A S++T +P +S +S+ +A VT L
Sbjct: 1965 HATSLPVTDASSVSTGHATPLPVTDASSVSTGHATPLPVTDTSS--VSTGQATPLPVTSL 2022
Query: 1754 LQGNLPLEKVLPQPRLGAKLEINRLPLP---LQTTSVGKTAPERNVEIPPSSPNPDGKGY 1810
+ LP + PLP L + S G T P +P +SP+ G+
Sbjct: 2023 SSASTGDTTPLPVTDTSSASTGQDTPLPVTSLSSVSTGDTTP-----LPVTSPSSASTGH 2077
Score = 54.3 bits (129), Expect = 1e-06
Identities = 214/1059 (20%), Positives = 357/1059 (33%), Gaps = 121/1059 (11%)
Query: 525 SPQEEMTVVIDQLEVCDSLIPSTSSMTHVSDTEHKESETAVETSTPKIKTGSSSLEGQFP 584
SP T L V D+ ST T + T+ + T TS P T SSS P
Sbjct: 3109 SPSSASTGHATSLPVTDTSSASTGDTTSLPVTDTSSAYTGDTTSLPVTDTSSSSTGDTTP 3168
Query: 585 NEGIAIDMELQSDPEEQLSENACISETSFSSE----SPEGACT--SLPSPGGETQSTSEE 638
L +A + T ++ SP A T + P P +T S S
Sbjct: 3169 LLVTETSSVSTGHATPLLVTDASSASTGHATPLHVTSPSSASTGDTTPVPVTDTSSVSTG 3228
Query: 639 SCTPASLETTFCSEVSSTENTDKYNQRNSTDENFHASLMSEISPISTSPEISEASLMSNL 698
TP L T S S+ + T + TD + ++ + P++ + +S M L
Sbjct: 3229 HATP--LPVTGLSSASTGDTT----RLPVTDISSASTGQATPLPVTNTSSVSTGDTMP-L 3281
Query: 699 PLTSEASPVSNLPLTSETSPMSDLPLTSETSSVSSMLLTSETTFVSSLPLPSETS-PISN 757
P+TS P ++ T + LP+TS +S+ + T SS T P+++
Sbjct: 3282 PVTS--------PSSASTGHATPLPVTSTSSASTGHATPVPVTSTSSASTGHTTPLPVTD 3333
Query: 758 SSINERMAHQQRKSPSVSEEPLSPQKDESSATAKPLGENLTSQQKNLSNTPEPIIMSSSS 817
+S + + P++ S+ PL + S + P+ +SS+
Sbjct: 3334 TS--------SASTGDTTPLPVTSPSSASTGHTTPLHVTIPSSASTGDTSTLPVTGASSA 3385
Query: 818 IAPEAFPSEDLHNKTLSQQTCKSHVDTEKPYPASIPELAS-----TEMIKVKNHSVLQRT 872
A P T S V T P + L+S T + V + S
Sbjct: 3386 STGHATPLP---------VTDTSSVSTGHATPLPVTSLSSVSTGDTTPLPVTDASSASTG 3436
Query: 873 EKKVLPSPLELSVFSEGTDNKGNELPSAKLQDKQYISSVDKAPFSEGSRNKTHKQGSTQS 932
+ LP V S + + G+ P + D +S+ P + +T
Sbjct: 3437 QATPLP------VTSLSSVSTGDTTPLL-VTDASSVSTGHATPLPVTDTSSASTGDTT-- 3487
Query: 933 RLETSHTSKSSEPSKSPDGIRNESRDS--EISKRKTAEQHSFGICKEKRARIEDDQSTRN 990
RL + TS +S +P + + S S + + + S + D S
Sbjct: 3488 RLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLLVTDASSVSTGHATPLPVTDTSSAST 3547
Query: 991 ISSSSPPEKEQPPREEPRVPPLKIQLSKIGPPFIIKSQPVSKPESRASTSTSVSGGRNTG 1050
++ P + + PL + + PV+ +++SVS G T
Sbjct: 3548 GDTTRLPVTDTSSASTGQATPLPVTIPSSSSSGHTTPLPVT-------STSSVSTGHVTP 3600
Query: 1051 ARTLADIKARAQQARAQREAAAAAAVAAAASIVSGAMGSPGEGGKTRTLAHIKEQTKAKL 1110
+ A + ++A A+ + S G L + + + A
Sbjct: 3601 LHVTSPSSASTGHVTPLPVTSTSSASTGHATPLLVTDASSVSTGHATPLP-VTDASSA-- 3657
Query: 1111 FAKHQARAHLFQTSKETRLPPPLSSKEGPPNLEVSSTPETKMEG-STGVIIVNPNCRSPS 1169
S P P++ + + P T + STG P + S
Sbjct: 3658 -------------STGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTDASS 3704
Query: 1170 NKSAHLRETTTVLQQSLNPSK---LPETATDLSVHSSDENIPVSHLSEKIVSSTSSENSS 1226
+ H + S++ LP T+ + +PV+ LS S+++ + +
Sbjct: 3705 ASTGHATPLPVTIPSSVSTGDTMPLPVTSPSSASTGHATPLPVTGLS----SASTGDTTP 3760
Query: 1227 VPMLFNKNSVPVSVCSTAISGAIKEHPFVSSVDKSSVLMSVDSANTTISACNISMLKTIQ 1286
+P+ T S A H V +S + D+ T + ++S T
Sbjct: 3761 LPV-------------TDTSSASTRHATPLPVTDTSSASTDDT--TRLPVTDVSSASTGH 3805
Query: 1287 GTDTPCIAIIPKCIESTPISATTEGSSISSSMDDKQLLISSSSASNLVSTQYTSVPTPSI 1346
T P + T T+ SS+S+ + S SSAS +T T S+
Sbjct: 3806 ATPLPVTSTSSASTGDTTPLPVTDTSSVSTGHATSLPVTSRSSASTGHATPLPVTDTSSV 3865
Query: 1347 GNN----LPNLSTSSVLIPPMGINNRFPSEKIAIPGSEEQATVSMGTTVRAALSCSDSVA 1402
LP STSSV G P + P S A+ T V + S S
Sbjct: 3866 STGHATPLPVTSTSSV---STGHATPLP---VTSPSS---ASTGHATPVPVTSTSSASTG 3916
Query: 1403 VTDSLVAHPTVAMFTGNMLTINSYDSPPKLSAESLDKNSGPRNRADNSGKPQQPP---GG 1459
T L ++ TG+ ++ SP SA D ++ P A ++ P
Sbjct: 3917 DTTPLPVTNASSLSTGHATPLH-VTSPS--SASRGDTSTLPVTDASSASTGHATPLPLTS 3973
Query: 1460 FAPAAINRSIPCKVIVDHSTTLTSSLSLTVSVESSEASLDLQGRPVRTEASVQPVACPQV 1519
+ + + P V S + + L V+ SS ++ D PV +S +
Sbjct: 3974 LSSVSTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTIPSSASSGHTTSL 4033
Query: 1520 SVISRPEPVANEGIDHSSTFIAASAAKQDSKTLPATCTS 1558
V G T +SA+ D+ LP T TS
Sbjct: 4034 PVTDASSVSTGHGTPLPVT-STSSASTGDTTPLPVTDTS 4071
Score = 50.1 bits (118), Expect = 2e-05
Identities = 195/1002 (19%), Positives = 352/1002 (35%), Gaps = 147/1002 (14%)
Query: 928 GSTQSRLETSHTSKSSEPSKSPDGIRNESRDSEISKRKTAEQHSFGICKEKRARIEDDQS 987
GST + LE T+ SS S +++ ++ S T++ + + + + + S
Sbjct: 48 GSTTATLEGQSTAASSRTSNQDISASSQNHQTK-STETTSKAQTDTLTQMMTSTLFSSPS 106
Query: 988 TRNISSSSPPEKEQPPREEPRVPPLKIQLSKIGPPFIIKSQPVSKPESRAST-----STS 1042
N+ ++PP++ S + ++ S+ ++ S ST TS
Sbjct: 107 VHNVMETAPPDEMTTSFP-----------SSVTNTLMMTSKTITMTTSTDSTLGNTEETS 155
Query: 1043 VSGGRNTGARTLADIKARAQQARAQREAAAAAAVAAAASIVSGAMGSPG--EGGKTRTLA 1100
+G ++ T A Q+ +++ + + +AS + S +T TL
Sbjct: 156 TAGTESSTPVTSAVSITAGQEGQSRTTSWRTSIQDTSASSQNHWTRSTQTTRESQTSTLT 215
Query: 1101 HIKEQTKAKLFAKHQARAHLFQ----------------------TSKETRLPPPLSSKEG 1138
H T + + H + Q TS++ + S G
Sbjct: 216 HRTTSTPSFSPSVHNVTGTVSQKTSPSGETATSSLCSVTNTSMMTSEKITVTTSTGSTLG 275
Query: 1139 PPNLEVSSTPETKM---EGSTGVIIVNPNCRSPSNKSAHLRETTTVLQQSLNPSKLPETA 1195
P E SS P T S ++ +P +SP+ S + TT ++ + ++ ET
Sbjct: 276 NPG-ETSSVPVTGSLMPVTSAALVTFDPEGQSPATFSRTSTQDTTAFSKN-HQTQSVETT 333
Query: 1196 TDLSVHSSDENIPVSHLSEKIVSSTSSENSS-------VPMLFNKNSVPVSVCSTAISGA 1248
+++ + PV+ + ++SS S N S P S P SV +T +
Sbjct: 334 RVSQINTLNTLTPVT--TSTVLSSPSGFNPSGTVSQETFPSGETTTSSPSSVSNTFL--- 388
Query: 1249 IKEHPFVSSVDKSSVLMSVD----SANTTISACNISMLKTIQGTDTPCIAIIPKCI---- 1300
+ F + S L + + S + TISA S + TI +DT A+ P +
Sbjct: 389 VTSKVFRMPTSRDSTLGNTEETSLSVSGTISAIT-SKVSTIWWSDTLSTALSPSSLPPKI 447
Query: 1301 ------ESTPISATT----EGSSISSSMDDKQLLI-------SSSSASNLVSTQYTSVPT 1343
+ + + TT E SS S + + + SS S+ + T +P+
Sbjct: 448 STAFHTQQSEGAETTGRPHERSSFSPGVSQEIFTLHETTTWPSSFSSKGHTTWSQTELPS 507
Query: 1344 PSIGNNLPNLSTSSVLIPPMGINNRFPSEKIAI--PG-----SEEQATVSMGTTVRAALS 1396
S G L T + G R PS+ AI PG S T+ T A
Sbjct: 508 TSTGA-ATRLVTGNPSTGTAGTIPRVPSKVSAIGEPGEPTTYSSHSTTLPKTTGAGAQTQ 566
Query: 1397 CSDSVAVT-DSLVAHPTVAMFTGNMLTINSYDSPPKLSAESLDK-----NSGPRNRADNS 1450
+ T ++L++ P+ ++ T + T S S P L + + ++ S
Sbjct: 567 WTQETGTTGEALLSSPSYSV-TQMIKTATSPSSSPMLDRHTSQQITTAPSTNHSTIHSTS 625
Query: 1451 GKPQQPPGGFAPAAINRSIPCKVIVDHSTTLTSSLSLTVSVESSEASLDLQGRPVRTEAS 1510
PQ+ P + P +T S ++ T +V + +S G + +
Sbjct: 626 TSPQESPA--VSQRGHTQAPQTTQESQTTRSVSPMTDTKTVTTPGSSFTASGH---SPSE 680
Query: 1511 VQPVACPQVSVISRPEPVANEGIDHSS----TFIAASAAKQDSKTLPATCTSLRE---LP 1563
+ P P +S + P A G H++ T + A+ + D+ P+ TSL + L
Sbjct: 681 IVPQDAPTISAATTFAP-APTGDGHTTQAPTTALQAAPSSHDATLGPSGGTSLSKTGALT 739
Query: 1564 LVPDKLNEPTAPSHNFAEQARGPAPFKS-------EADTTCSNQYNPSNRICWNDDGMRS 1616
L ++ P P + + +P + +A++T ++ ++ + S
Sbjct: 740 LANSVVSTPGGPEGQWTSASASTSPDTAAAMTHTHQAESTEASGQTQTSEPASSGSRTTS 799
Query: 1617 TGQPLVTHSGSSKQKEYLEQSCPKAIKTEHANYLNVSELHPRNLVTNV--------ALPV 1668
G + SG+S + + +T + + H T + A+PV
Sbjct: 800 AGTATPSSSGASGTTPSGSEGISTSGETTRFSSNPSRDSHTTQSTTELLSASASHGAIPV 859
Query: 1669 KS-------------ELHEADKGFRMDTEDFP-GPELPPPAAEGASSVQQTQNMKASTSS 1714
+ L EA R + P P P S + QTQ + S S
Sbjct: 860 STGMASSIVPGTFHPTLSEASTAGRPTGQSSPTSPSASPQETAAISRMAQTQRTRTSRGS 919
Query: 1715 PMEEAISLATDALKRV----PGAGSSGCRLSSVEAN--NPLVTQLLQGNLPLEKVLPQPR 1768
S ATD V P S+G E + +P + + P P
Sbjct: 920 DTISLASQATDTFSTVPPTPPSITSTGLTSPQTETHTLSPSGSGKTFTTALISNATPLPV 979
Query: 1769 LGAKLEINRLPLPLQTTSVGKTAPERNVEIPPSSPNPDGKGY 1810
A PL T + +P +SP+ G+
Sbjct: 980 TYASSASTGHTTPLHVTDASSVSTGHATPLPVTSPSSVSTGH 1021
Score = 37.4 bits (85), Expect = 0.17
Identities = 59/252 (23%), Positives = 96/252 (38%), Gaps = 17/252 (6%)
Query: 537 LEVCDSLIPSTSSMTHVSDTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMELQS 596
L V D+ ST T + T T T P T S+S G A + + S
Sbjct: 3953 LPVTDASSASTGHATPLPLTSLSSVSTGDTTPLPVTDTSSAST-------GQATPLPVTS 4005
Query: 597 DPEEQLSENACISETSFSSESPEGACTSLPSPGGETQSTSEESCTPASLETTFCSEVSST 656
+ + T SS S G TSLP + ST + P T S S+
Sbjct: 4006 LSSVSTGDTTPLPVTIPSSAS-SGHTTSLPVTDASSVSTGHGTPLPV----TSTSSASTG 4060
Query: 657 ENTDKYNQRNSTDENFHASLMSEISPISTSPEISEASLMSNLPL--TSEASPVSNLPLTS 714
+ T S+ HA+ + S S + +++L T A+P++ TS
Sbjct: 4061 DTTPLPVTDTSSASTGHATPLPVTDTSSASTGHATPLPVTSLSSVSTGHATPLAVSSATS 4120
Query: 715 ETSPMSDLPLTSETSSVSSMLLTSETTFVSSLPLPSETSPISNSSINERMAHQQRKSPSV 774
++ SD PL ET +++ L ++ ++ P TS S+I H + + +
Sbjct: 4121 ASTVSSDSPLKMETPGMTTPSLKTDGGRRTATSPPPTTSQTIISTIPSTAMHTRSTAAPI 4180
Query: 775 SEEPLSPQKDES 786
P+ P++ S
Sbjct: 4181 ---PILPERGVS 4189
>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
[Homo sapiens]
Length = 1412
Score = 79.7 bits (195), Expect = 3e-14
Identities = 185/888 (20%), Positives = 322/888 (36%), Gaps = 103/888 (11%)
Query: 518 KIEGKSESPQEEMTVVIDQLEVCDSLIPSTSS----MTHVSDTEHKESETAVETSTPKIK 573
K E SES EE + ++ +L+ + +S + KES P K
Sbjct: 257 KPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGK 316
Query: 574 TGSSSLEGQFPNEGIAIDMELQSDPEEQLSENACISETSFSSESPEGACTSLP---SPGG 630
TG + + Q + + QS EE SE ++ S ++P+ S P SP
Sbjct: 317 TGPAVAKAQAGKR----EEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRK 372
Query: 631 ETQSTSEESCTPASLETTFCSEVSSTENTDKYNQRNSTDENFHASLMSEISPISTSPEIS 690
PA+ + + + ++ + + +S E A +++ P+ SP++
Sbjct: 373 GAAPAPPRKTGPAAAQVQVGKQEEDSRSSSE--ESDSDREALAAMNAAQVKPLGKSPQVK 430
Query: 691 EASLMSNLPLTSEASPVSNLPLTSETSPMSDLPLTSETSSVSSMLLTSETTFVSSLPLPS 750
AS M PL A PV + T P + + E S SS E++ S +P+
Sbjct: 431 PASTMGMGPLGKGAGPVPPGKVGPAT-PSAQVGKWEEDSESSS----EESSDSSDGEVPT 485
Query: 751 ETSPISNSSINERMAHQQRKSPSVSEEPLSPQKDESSATAKPLGENLTSQQKNLSNTPE- 809
+P S+ + + SP+ + KP+ + +S++ + S E
Sbjct: 486 AVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEE 545
Query: 810 -PIIMSSSSIAP-------EAFPSEDLHNKTLSQQTCKSHVDTEKPYPA--------SIP 853
P M+++ P +A P + N T S + V T+ P A S P
Sbjct: 546 APAAMTAAQAKPALKIPQTKACPKKT--NTTASAKVAPVRVGTQAPRKAGTATSPAGSSP 603
Query: 854 ELASTEMIKVKNHSVLQRTEKKVLPSPLELSVFSEGTDNKGNELPSAKLQDKQYISSVDK 913
+A ++ S + ++ + + L ++V + KG ++ +A + K +
Sbjct: 604 AVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQ-GT 662
Query: 914 APFSEGSRNKTHKQGSTQSRLETSHTSKSSEPSKSPDGIRNESRDSEISKRKTAEQHSFG 973
AP G T TQ + E S+SSE + + S +KT + +
Sbjct: 663 APVLPGKTGPT----VTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPA 718
Query: 974 ICKEKRARIEDDQSTRNISSSS-----PPEKEQPPREEPRVPPL----KIQLSKIGPPFI 1024
+ A+ + +++++ P K +PP P+ + + +G
Sbjct: 719 AARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVA 778
Query: 1025 IKSQPVSKPESRASTSTSVSGGRNTGARTLADIK--ARAQQARAQREAAAAAAVAAAASI 1082
+Q + PE + +S S A TLA +K + Q RA A + AA
Sbjct: 779 TAAQAQTGPEEDSGSSEEESDSEEE-AETLAQVKPSGKTHQIRAALAPAKESPRKGAAPT 837
Query: 1083 VSGAMG-SPGEGGKTRTLAHIKEQTKAKLFAKHQARAHLFQTSKETRLPP---------P 1132
G G S + GK E++ + A TS + PP P
Sbjct: 838 PPGKTGPSAAQAGKQDDSGSSSEESDS------DGEAPAAVTSAQVIKPPLIFVDPNRSP 891
Query: 1133 LSSKEGPPNLEVSSTP-----------ETKMEGSTGVIIVNPNCRSPSNKSAHLRETTTV 1181
P + +STP + E +I C +P + T V
Sbjct: 892 AGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIR------TNVV 945
Query: 1182 LQQSLNPSKLPETATDLSVHSSDENIPVS--HLSEKIVSSTSSEN-SSVPMLFNKNSVPV 1238
+ +P P+ A+ SS E+ +S E + S +N +S+P+ V
Sbjct: 946 TMPTAHPRIAPK-ASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLA 1004
Query: 1239 SVCSTAISGAIKEHPFVSSVDKS-SVLMSVDSANTTISACNISMLKTIQGTDTPCIAIIP 1297
S A + P S VD + L + +T++ A + L+ P +
Sbjct: 1005 QKASEAQPPVARTQP-SSGVDSAVGTLPATSPQSTSVQAKGTNKLRK---PKLPEVQQAT 1060
Query: 1298 KCIESTPISATTEGSSISSSMDDKQLLISSSSASNLVSTQYTSVPTPS 1345
K ES+ S + SS S S +D + + SA LV PTPS
Sbjct: 1061 KAPESSDDSEDSSDSS-SGSEEDGEGPQGAKSAHTLVG------PTPS 1101
Score = 38.5 bits (88), Expect = 0.075
Identities = 188/1032 (18%), Positives = 335/1032 (32%), Gaps = 152/1032 (14%)
Query: 496 EDNLESCVMMNDV--LETLPHIEVKIE-GKSESPQEEMTVVIDQLEVCDSLIPSTSSMTH 552
E + + C + V L+ H + E G+ +E+ + + V D + S SS
Sbjct: 32 EQSGQKCFLAQPVTLLDIYTHWQQTSELGRKRKAEEDAALQAKKTRVSDPISTSESS--- 88
Query: 553 VSDTEHKESETAVETSTPKIK-TGSSSLEGQFPNEGIAIDMELQSDPEEQLSENACISET 611
E +E+E +TP++ T SS L P+ S E+ +E +T
Sbjct: 89 ---EEEEEAEAETAKATPRLASTNSSVLGADLPS----------SMKEKAKAETEKAGKT 135
Query: 612 SFSSESPEGACTSLPSPGGETQSTSEESCTPASLETTFCSEVSSTENTDKYNQRNSTDEN 671
S P T G++ S E S TT SE + +
Sbjct: 136 GNSMPHPATGKTVANLLSGKSPRKSAE----PSANTTLVSETEEEGSVPAFGAAAKPGMV 191
Query: 672 FHASLMSEISPISTSPEISEASLMSN---LPLTSEASPVSNLP--------------LTS 714
S S+S + ++ + ++ L + + ++P P + S
Sbjct: 192 SAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVAS 251
Query: 715 ET---SPMSDLPLTSETSSVS-----------SMLLTSETTFVSSLPLPSETSPISNSS- 759
+T P D +SE SS S + +T+ V + P++ SP ++
Sbjct: 252 QTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAP 311
Query: 760 ----------INERMAHQQRKSPSVSEEPLSPQKDESSATAKPLGE--------NLTSQQ 801
+ ++ S S SEE S ++E+ A AKP G+ +
Sbjct: 312 APPGKTGPAVAKAQAGKREEDSQSSSEE--SDSEEEAPAQAKPSGKAPQVRAASAPAKES 369
Query: 802 KNLSNTPEPIIMSSSSIAPEAFPSEDLHNKTLSQQTCKSHVDTEKPYPASIPELASTEMI 861
P P + + A ++ +++ S+++ A + L + +
Sbjct: 370 PRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQV 429
Query: 862 KVKNHSVLQRTEKKVLPSPLELSVFSEGTDNKGNELPSA---KLQDKQYISSVDKAPFSE 918
K + + K P P G PSA K ++ SS + + S+
Sbjct: 430 KPASTMGMGPLGKGAGPVP---------PGKVGPATPSAQVGKWEEDSESSSEESSDSSD 480
Query: 919 GSRNKTHKQGSTQSRLETSHTSKSSEPSKSPDGIRNESRDSEISKRKTAEQHSFGICKEK 978
G +S +S P+K P Q + + +
Sbjct: 481 GEVPTAVAPAQEKSLGNILQAKPTSSPAKGP------------------PQKAGPVAVQV 522
Query: 979 RARIEDDQSTRNISSSSPPEKEQPPREEPRV---PPLKIQLSKIGPPFIIKSQPVSKPES 1035
+A D S + SS + E+ P P LKI +K P ++
Sbjct: 523 KAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACP-----------KKT 571
Query: 1036 RASTSTSVSGGRNTGARTLADIKARAQQARAQREAAAAAAVAAAASIVSGAMGSPGEGGK 1095
+ S V+ R T A KA + A A A A S + S E K
Sbjct: 572 NTTASAKVAPVR---VGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEK 628
Query: 1096 TRTLAHIKEQTKAKLFAKHQARAHLFQTSKETRLPPPLSSKEGPPNLEVSSTPETKMEGS 1155
T + + + +A + + S P L K GP +V + + E S
Sbjct: 629 TGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESS 688
Query: 1156 TGVIIVNPNCRSPSNKSAHLRETTTVLQQSLNPSKLPETATDLSVHSSDENIPVSHLSE- 1214
SP+ +++T Q NP+ + ++ + + + + ++
Sbjct: 689 EEESDSEEAAASPAQVKTSVKKT----QAKANPAAARAPSAKGTISAPGKVVTAAAQAKQ 744
Query: 1215 ----KIVSSTSSENSSVPMLFNKNSVPVSVCSTAISGAIKEHPFVSSVDKSSVLMSVDSA 1270
K+ + +S + SVP + A + + P S S + A
Sbjct: 745 RSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEA 804
Query: 1271 NTTISACNISMLKTIQGTDTPCIAIIPKCIESTPISATTEGSSISSSMDDKQLLISSSSA 1330
T I+ P K TP T ++ + DD SSS
Sbjct: 805 ETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSG---SSSEE 861
Query: 1331 SNLVSTQYTSVPTPSIGNNLPNLSTSSVLIPPMGI--NNRFPSEKIAIPGSEEQATVSMG 1388
S+ S G ++++ V+ PP+ NR P+ A P + A+
Sbjct: 862 SD------------SDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRK 909
Query: 1389 TTVRAALSCSDSVAVTDSLVAHPTVAMFTG---NMLTINSYDSPPKLSAESLDKNSGPRN 1445
+ + S S D V T + G N++T+ + A +S +
Sbjct: 910 ARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKES 969
Query: 1446 RADNSGKPQQPP 1457
+ GK Q+ P
Sbjct: 970 SRISDGKKQEGP 981
Score = 32.3 bits (72), Expect = 5.4
Identities = 42/198 (21%), Positives = 79/198 (39%), Gaps = 20/198 (10%)
Query: 38 QKEGLKETSGTSP-----LACLNAMLHTNTRIGDGTFFKIPGKSG-----LYALKKEESS 87
+K GL T G + L A + +G GT +PGK+G + A K+E+S
Sbjct: 627 EKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSE 686
Query: 88 CPADGTLDLVCESELDGTDMAEANAHGEENGVCSKQVTDEASSTRDSSLTNTAVQSKLVS 147
E E D + A + A + + ++ + A++ S+ + K+V+
Sbjct: 687 SS---------EEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVT 737
Query: 148 SFQQHTKKALKQALRQQQKRRNGVSMMVNK-TVPRVVLTPLKVSDEQSDSPSGSESKNGE 206
+ Q +++ + + +N + +VP V + Q+ S S E
Sbjct: 738 AAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEE 797
Query: 207 ADSSDKEMKHGQKSPTGK 224
+DS ++ Q P+GK
Sbjct: 798 SDSEEEAETLAQVKPSGK 815
>gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b [Homo
sapiens]
Length = 1411
Score = 78.6 bits (192), Expect = 7e-14
Identities = 180/888 (20%), Positives = 321/888 (36%), Gaps = 104/888 (11%)
Query: 518 KIEGKSESPQEEMTVVIDQLEVCDSLIPSTSS----MTHVSDTEHKESETAVETSTPKIK 573
K E SES EE + ++ +L+ + +S + KES P K
Sbjct: 257 KPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGK 316
Query: 574 TGSSSLEGQFPNEGIAIDMELQSDPEEQLSENACISETSFSSESPEGACTSLP---SPGG 630
TG + + Q + + QS EE SE ++ S ++P+ S P SP
Sbjct: 317 TGPAVAKAQAGKR----EEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRK 372
Query: 631 ETQSTSEESCTPASLETTFCSEVSSTENTDKYNQRNSTDENFHASLMSEISPISTSPEIS 690
PA+ + + + ++ + + +S E A +++ P+ SP++
Sbjct: 373 GAAPAPPRKTGPAAAQVQVGKQEEDSRSSSE--ESDSDREALAAMNAAQVKPLGKSPQVK 430
Query: 691 EASLMSNLPLTSEASPVSNLPLTSETSPMSDLPLTSETSSVSSMLLTSETTFVSSLPLPS 750
AS M PL A PV + T P + + E S SS E++ S +P+
Sbjct: 431 PASTMGMGPLGKGAGPVPPGKVGPAT-PSAQVGKWEEDSESSS----EESSDSSDGEVPT 485
Query: 751 ETSPISNSSINERMAHQQRKSPSVSEEPLSPQKDESSATAKPLGENLTSQQKNLSNTPE- 809
+P S+ + + SP+ + KP+ + +S++ + S E
Sbjct: 486 AVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEE 545
Query: 810 -PIIMSSSSIAP-------EAFPSEDLHNKTLSQQTCKSHVDTEKPYPA--------SIP 853
P M+++ P +A P + N T S + V T+ P A S P
Sbjct: 546 APAAMTAAQAKPALKIPQTKACPKKT--NTTASAKVAPVRVGTQAPRKAGTATSPAGSSP 603
Query: 854 ELASTEMIKVKNHSVLQRTEKKVLPSPLELSVFSEGTDNKGNELPSAKLQDKQYISSVDK 913
+A ++ S + ++ + + L ++V + KG ++ +A + K +
Sbjct: 604 AVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQ-GT 662
Query: 914 APFSEGSRNKTHKQGSTQSRLETSHTSKSSEPSKSPDGIRNESRDSEISKRKTAEQHSFG 973
AP G T TQ + E S+SSE + + S +KT + +
Sbjct: 663 APVLPGKTGPT----VTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPA 718
Query: 974 ICKEKRARIEDDQSTRNISSSS-----PPEKEQPPREEPRVPPL----KIQLSKIGPPFI 1024
+ A+ + +++++ P K +PP P+ + + +G
Sbjct: 719 AARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVA 778
Query: 1025 IKSQPVSKPESRASTSTSVSGGRNTGARTLADIK--ARAQQARAQREAAAAAAVAAAASI 1082
+Q + PE + +S S A TLA +K + Q RA A + AA
Sbjct: 779 TAAQAQTGPEEDSGSSEEESDSEEE-AETLAQVKPSGKTHQIRAALAPAKESPRKGAAPT 837
Query: 1083 VSGAMG-SPGEGGKTRTLAHIKEQTKAKLFAKHQARAHLFQTSKETRLPP---------P 1132
G G S + GK E++ + A TS + PP P
Sbjct: 838 PPGKTGPSAAQAGKQDDSGSSSEESDS------DGEAPAAVTSAQVIKPPLIFVDPNRSP 891
Query: 1133 LSSKEGPPNLEVSSTP-----------ETKMEGSTGVIIVNPNCRSPSNKSAHLRETTTV 1181
P + +STP + E +I C +P + T V
Sbjct: 892 AGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIR------TNVV 945
Query: 1182 LQQSLNPSKLPETATDLSVHSSDENIPVS--HLSEKIVSSTSSEN-SSVPMLFNKNSVPV 1238
+ +P P+ A+ SS E+ +S E + S +N +S+P+ V
Sbjct: 946 TMPTAHPRIAPK-ASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLA 1004
Query: 1239 SVCSTAISGAIKEHPFVSSVDKS-SVLMSVDSANTTISACNISMLKTIQGTDTPCIAIIP 1297
S A + P S VD + L + +T++ A + L+ P + +
Sbjct: 1005 QKASEAQPPVARTQP-SSGVDSAVGTLPATSPQSTSVQAKGTNKLR------KPKLPEVQ 1057
Query: 1298 KCIESTPISATTEGSSISSSMDDKQLLISSSSASNLVSTQYTSVPTPS 1345
+ ++ S +E SS SSS ++ + +T PTPS
Sbjct: 1058 QATKAPESSDDSEDSSDSSSGSEE-----DGEGPQGAKSAHTLGPTPS 1100
Score = 38.5 bits (88), Expect = 0.075
Identities = 188/1032 (18%), Positives = 335/1032 (32%), Gaps = 152/1032 (14%)
Query: 496 EDNLESCVMMNDV--LETLPHIEVKIE-GKSESPQEEMTVVIDQLEVCDSLIPSTSSMTH 552
E + + C + V L+ H + E G+ +E+ + + V D + S SS
Sbjct: 32 EQSGQKCFLAQPVTLLDIYTHWQQTSELGRKRKAEEDAALQAKKTRVSDPISTSESS--- 88
Query: 553 VSDTEHKESETAVETSTPKIK-TGSSSLEGQFPNEGIAIDMELQSDPEEQLSENACISET 611
E +E+E +TP++ T SS L P+ S E+ +E +T
Sbjct: 89 ---EEEEEAEAETAKATPRLASTNSSVLGADLPS----------SMKEKAKAETEKAGKT 135
Query: 612 SFSSESPEGACTSLPSPGGETQSTSEESCTPASLETTFCSEVSSTENTDKYNQRNSTDEN 671
S P T G++ S E S TT SE + +
Sbjct: 136 GNSMPHPATGKTVANLLSGKSPRKSAE----PSANTTLVSETEEEGSVPAFGAAAKPGMV 191
Query: 672 FHASLMSEISPISTSPEISEASLMSN---LPLTSEASPVSNLP--------------LTS 714
S S+S + ++ + ++ L + + ++P P + S
Sbjct: 192 SAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVAS 251
Query: 715 ET---SPMSDLPLTSETSSVS-----------SMLLTSETTFVSSLPLPSETSPISNSS- 759
+T P D +SE SS S + +T+ V + P++ SP ++
Sbjct: 252 QTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAP 311
Query: 760 ----------INERMAHQQRKSPSVSEEPLSPQKDESSATAKPLGE--------NLTSQQ 801
+ ++ S S SEE S ++E+ A AKP G+ +
Sbjct: 312 APPGKTGPAVAKAQAGKREEDSQSSSEE--SDSEEEAPAQAKPSGKAPQVRAASAPAKES 369
Query: 802 KNLSNTPEPIIMSSSSIAPEAFPSEDLHNKTLSQQTCKSHVDTEKPYPASIPELASTEMI 861
P P + + A ++ +++ S+++ A + L + +
Sbjct: 370 PRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQV 429
Query: 862 KVKNHSVLQRTEKKVLPSPLELSVFSEGTDNKGNELPSA---KLQDKQYISSVDKAPFSE 918
K + + K P P G PSA K ++ SS + + S+
Sbjct: 430 KPASTMGMGPLGKGAGPVP---------PGKVGPATPSAQVGKWEEDSESSSEESSDSSD 480
Query: 919 GSRNKTHKQGSTQSRLETSHTSKSSEPSKSPDGIRNESRDSEISKRKTAEQHSFGICKEK 978
G +S +S P+K P Q + + +
Sbjct: 481 GEVPTAVAPAQEKSLGNILQAKPTSSPAKGP------------------PQKAGPVAVQV 522
Query: 979 RARIEDDQSTRNISSSSPPEKEQPPREEPRV---PPLKIQLSKIGPPFIIKSQPVSKPES 1035
+A D S + SS + E+ P P LKI +K P ++
Sbjct: 523 KAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACP-----------KKT 571
Query: 1036 RASTSTSVSGGRNTGARTLADIKARAQQARAQREAAAAAAVAAAASIVSGAMGSPGEGGK 1095
+ S V+ R T A KA + A A A A S + S E K
Sbjct: 572 NTTASAKVAPVR---VGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEK 628
Query: 1096 TRTLAHIKEQTKAKLFAKHQARAHLFQTSKETRLPPPLSSKEGPPNLEVSSTPETKMEGS 1155
T + + + +A + + S P L K GP +V + + E S
Sbjct: 629 TGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESS 688
Query: 1156 TGVIIVNPNCRSPSNKSAHLRETTTVLQQSLNPSKLPETATDLSVHSSDENIPVSHLSE- 1214
SP+ +++T Q NP+ + ++ + + + + ++
Sbjct: 689 EEESDSEEAAASPAQVKTSVKKT----QAKANPAAARAPSAKGTISAPGKVVTAAAQAKQ 744
Query: 1215 ----KIVSSTSSENSSVPMLFNKNSVPVSVCSTAISGAIKEHPFVSSVDKSSVLMSVDSA 1270
K+ + +S + SVP + A + + P S S + A
Sbjct: 745 RSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEA 804
Query: 1271 NTTISACNISMLKTIQGTDTPCIAIIPKCIESTPISATTEGSSISSSMDDKQLLISSSSA 1330
T I+ P K TP T ++ + DD SSS
Sbjct: 805 ETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSG---SSSEE 861
Query: 1331 SNLVSTQYTSVPTPSIGNNLPNLSTSSVLIPPMGI--NNRFPSEKIAIPGSEEQATVSMG 1388
S+ S G ++++ V+ PP+ NR P+ A P + A+
Sbjct: 862 SD------------SDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRK 909
Query: 1389 TTVRAALSCSDSVAVTDSLVAHPTVAMFTG---NMLTINSYDSPPKLSAESLDKNSGPRN 1445
+ + S S D V T + G N++T+ + A +S +
Sbjct: 910 ARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKES 969
Query: 1446 RADNSGKPQQPP 1457
+ GK Q+ P
Sbjct: 970 SRISDGKKQEGP 981
Score = 32.3 bits (72), Expect = 5.4
Identities = 42/198 (21%), Positives = 79/198 (39%), Gaps = 20/198 (10%)
Query: 38 QKEGLKETSGTSP-----LACLNAMLHTNTRIGDGTFFKIPGKSG-----LYALKKEESS 87
+K GL T G + L A + +G GT +PGK+G + A K+E+S
Sbjct: 627 EKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSE 686
Query: 88 CPADGTLDLVCESELDGTDMAEANAHGEENGVCSKQVTDEASSTRDSSLTNTAVQSKLVS 147
E E D + A + A + + ++ + A++ S+ + K+V+
Sbjct: 687 SS---------EEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVT 737
Query: 148 SFQQHTKKALKQALRQQQKRRNGVSMMVNK-TVPRVVLTPLKVSDEQSDSPSGSESKNGE 206
+ Q +++ + + +N + +VP V + Q+ S S E
Sbjct: 738 AAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEE 797
Query: 207 ADSSDKEMKHGQKSPTGK 224
+DS ++ Q P+GK
Sbjct: 798 SDSEEEAETLAQVKPSGK 815
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 77.4 bits (189), Expect = 1e-13
Identities = 95/477 (19%), Positives = 191/477 (40%), Gaps = 6/477 (1%)
Query: 520 EGKSESPQEEMTVVIDQLEVCDSLIPSTSSMTHVSDTEHKESETAVETSTPKIKTGSSSL 579
+GKS+S + + + + DS +S SD++ +S+++ + + + +SS
Sbjct: 544 KGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSD 603
Query: 580 EGQFPNEGIAIDMELQSDPEEQLSENACISETSFSSESPEGACTSLPSPGGETQSTSEES 639
+ + D SD + S++ S S S + +S S ++ +S S
Sbjct: 604 SSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSS 663
Query: 640 CTPASLETTFCSEVSSTENTDKYNQRNSTDENFHASLMSEISPISTSPEISEASLMSNLP 699
+ S +++ S+ SS+ ++ + + + ++ ++S S+ S S S + ++
Sbjct: 664 NSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNS 723
Query: 700 LTSEASPVSNLPLTSETSPMSDLPLTSETSSVSSMLLTSETTFVSSLPLPSETSPISNSS 759
S++S S+ +S +S SD +S +S S +S ++ S S++S SNSS
Sbjct: 724 SDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSS 783
Query: 760 INERMAHQQRKSPSVSEEPLSPQKDES-SATAKPLGENLTSQQKNLSNTPEPIIMSSSSI 818
+ ++ S S + S D S S+ + + +S N S++ + S SS
Sbjct: 784 DSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSD 843
Query: 819 APEAFPSEDLHNKTLSQQTCKSHVDTEKPYPASIPELASTEMIKVKNHSVLQRTEKKVLP 878
+ ++ D + S + S S S++ + N S +
Sbjct: 844 SSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDS 903
Query: 879 SPLELSVFSEGTDNKGNELPSAKLQDKQYISSVDKAPFSEGSRNKTHKQGSTQSRLETSH 938
+ S S+ +D+ + S +S D + S+ S + S ++S+
Sbjct: 904 DSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSS-----DSSN 958
Query: 939 TSKSSEPSKSPDGIRNESRDSEISKRKTAEQHSFGICKEKRARIEDDQSTRNISSSS 995
+S SS S S D ++S DS S + S + D S + SS S
Sbjct: 959 SSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDS 1015
Score = 76.6 bits (187), Expect = 2e-13
Identities = 100/475 (21%), Positives = 192/475 (40%), Gaps = 25/475 (5%)
Query: 520 EGKSESPQEEMTVVIDQLEVCDSLIPSTSSMTHVSDTEHKESETAVETSTPKIKTGSSSL 579
+ + S + + D + DS S S ++ SD+ + + S+ + SS
Sbjct: 825 DSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSD 884
Query: 580 EGQFPNEGIAIDMELQSDPEEQLSENAC----------ISETSFSSESPEGACTSLPSPG 629
+ N + D SD + S N+ SE+S SS++ + +S S
Sbjct: 885 SNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDS 944
Query: 630 GETQSTSEESCTPASLETTFCSEVSSTENTDKYNQRNSTD-----ENFHASLMSEISPIS 684
++ +S S + S +++ S+ S + ++D + NS+D ++ +S S+ S S
Sbjct: 945 SDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSS 1004
Query: 685 TSPEISEASLMSNLPLTSEASPVSNLPLTSETSPMSDLPLTSETSSVSSMLLTSETTFVS 744
S + S++S SN +S +S SN +S++S SD +S++S S +S+++ S
Sbjct: 1005 DSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1064
Query: 745 SLPLPSETSPISNSSINERMAHQQRKSPSVSEEPLSPQKD--------ESSATAKPLGEN 796
S++S S+SS + + S S S D +SS ++ +
Sbjct: 1065 DSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSS 1124
Query: 797 LTSQQKNLSNTPEPIIMSSSSIAPEAFPSEDLHNKTLSQQTCKSHVDTEKPYPASIPELA 856
+S + S++ + S SS + E+ S D + + S + S D+ +S +
Sbjct: 1125 DSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSS-DSSDSSDSSNSSDS 1183
Query: 857 STEMIKVKNHSVLQRTEKKVLPSPLELSVFSEGTDNKGNELPSAKLQDKQYISSVDKAPF 916
S + ++ + S S+ +D+ + S + S D +
Sbjct: 1184 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDS 1243
Query: 917 SEGSRNKTHKQGSTQSRLETSHTSKSSEPSKSPDGIRNESRDSEISKRKTAEQHS 971
S+ S + S S + +S SKS +G N S DS+ + HS
Sbjct: 1244 SDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGS-DSDSDSEGSDSNHS 1297
Score = 35.8 bits (81), Expect = 0.49
Identities = 98/534 (18%), Positives = 196/534 (36%), Gaps = 45/534 (8%)
Query: 917 SEGSRNKTHKQGSTQSRLETSHTSKSSEPSKSPDGIRNESRDSEISKRKTAEQHSFGICK 976
S+ + K+ S S ++S++S SS+ S S N S DS+ S +++
Sbjct: 540 SDSGKGKSDSSDSDSS--DSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSD 597
Query: 977 EKRARIEDDQSTRNISSSSPPEKEQPPREEPRVPPLKIQLSKIGPPFIIKSQPVSKPESR 1036
+ D S + SS S + SK ES
Sbjct: 598 SSNSSDSSDSSDSSDSSDSSDSSDS-------------------------KSDSSKSESD 632
Query: 1037 ASTSTSVSGGRNTGARTLADIKARAQQARAQREAAAAAAVAAAASIVSGAMGSPGEGGKT 1096
+S S S S ++ + +D + + + + ++ + ++ S S + + +
Sbjct: 633 SSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDS 692
Query: 1097 RTLAHIKEQTKAKLFAKHQARAHLFQTSKETRLPPPLSSKEGPPNLEVSSTPETKMEGST 1156
++ E + + + + ++ SS N SS + S
Sbjct: 693 SDSSNSSESSDSSDSSDSDSSDSSDSSNSN-------SSDSDSSNSSDSSDSSNSSDSSD 745
Query: 1157 GVIIVNPNCRSPSNKSAHLRETTTVLQQSLNPSKLPETATDLSVHSSDENIPVSHLSEKI 1216
N + S S+ S++ +++ S + + ++ S +SSD + S+ S+
Sbjct: 746 SSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSS-DSSNSSDSS 804
Query: 1217 VSSTSSENSSVPMLFNKNSVPVSVCSTAISGAIKEHPFVSSVDKSSVLMSVDSANTTISA 1276
SS SS++S + NS S S + + SS SS DS+N + S+
Sbjct: 805 NSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSS--DSSDGSDSDSSNRSDSS 862
Query: 1277 CNISMLKTIQGTDTPCIAIIPKCIESTPISATTEGSSISSSMDDKQLLISSSSASNLVST 1336
+ + +++ + ES+ S +++ S+ SS D SS S+ + S+
Sbjct: 863 NSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSN-SSDSDSSDSSNSSDSSDSSNSS 921
Query: 1337 QYTSVPTPSIGNNLPNLSTSSVLIPPMGINNRFPSEKIAIPGSEEQATVSMGTTVRAALS 1396
+ S +N + S SS +N S + + ++ S + + +
Sbjct: 922 DSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSN 981
Query: 1397 CSDSVAVTDSLVAHPTVAMFTGNMLTINSYDSPPKLSAESLDKNSGPRNRADNS 1450
SDS +DS + + + + NS DS + +S N +D+S
Sbjct: 982 SSDSSDSSDS-------SDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSS 1028
>gi|83367077 mucin 16 [Homo sapiens]
Length = 14507
Score = 77.0 bits (188), Expect = 2e-13
Identities = 254/1278 (19%), Positives = 473/1278 (37%), Gaps = 196/1278 (15%)
Query: 360 EKLGMSREESVKLTTG------PNNAGAQSSSSCGTSGLPVSAQTALAEQQPKSMKSPAS 413
E + RE + LT G NA + +S S +P ++ + S +
Sbjct: 6937 ETTKIKRESTYSLTPGLRETSISQNASFSTDTSIVLSEVPTGTTAEVSRTEVTSSGRTSI 6996
Query: 414 PEPGFCATLCPMVEIPPKDIMAE---LESEDILIPEESVIQEEIAEE---VETSICECQD 467
P P L + + A ES ++ IP ++ +++ ++TS + Q
Sbjct: 6997 PGPSQSTVLPEISTRTMTRLFASPTMTESAEMTIPTQTGPSGSTSQDTLTLDTSTTKSQA 7056
Query: 468 ENHKTIPEFSEEAESLTNSHEEP-----QIAPPEDNLESCVMMNDVLETLPHIEVKIEGK 522
+ H T+ + +E T P Q +P +N S LP + + +
Sbjct: 7057 KTHSTLTQRFPHSEMTTLMSRGPGDMSWQSSPSLENPSS----------LPSL-LSLPAT 7105
Query: 523 SESPQEEMTVVIDQLEVCDSLIPSTSSMTH--VSDTEHKESETAVETSTP---------K 571
+ P T+ + + S +P TS +T V+ T+ + + TS+P +
Sbjct: 7106 TSPPPISSTLPVT---ISSSPLPVTSLLTSSPVTTTDMLHTSPELVTSSPPKLSHTSDER 7162
Query: 572 IKTG--SSSLEGQFPNEGIAI-DMELQSDPEEQLSENACISETSFSSESPEGACTSLPSP 628
+ TG +++ E P+ A ++E+ S E S SETS TS
Sbjct: 7163 LTTGKDTTNTEAVHPSTNTAASNVEIPSSGHESPSSALADSETS--------KATSPMFI 7214
Query: 629 GGETQSTSEESCTPASLETTFCSEVSSTENTDKYNQRNSTDENFHA----SLMSEISPIS 684
+ T+ TP LET+ + S + + K + S+ E A +++SE+S I
Sbjct: 7215 TSTQEDTTVAISTPHFLETSRIQKESISSLSPKLRETGSSVETSSAIETSAVLSEVS-IG 7273
Query: 685 TSPEISEASLMSNLPLTSEASPVSN-LPLTSETSPMSDLPLTSETSSVSSMLLTSET--- 740
+ EIS + S+ + S S LP S T + P + + S M + ++T
Sbjct: 7274 ATTEISRTEVTSSSRTSISGSAESTMLPEISTTRKIIKFPTSPILAESSEMTIKTQTSPP 7333
Query: 741 --TFVSSLPLPSETSP---ISNSSINERMAHQQ-----RKSPSVSEEPLSPQKDESSATA 790
T S+ L + T+P I++S++ +R+ H + + P S +E+S +
Sbjct: 7334 GSTSESTFTLDTSTTPSLVITHSTMTQRLPHSEITTLVSRGAGDVPRPSSLPVEETSPPS 7393
Query: 791 KPLGENLTSQQKNLSNT-PEPIIMSSSSIAPEAFPSEDLHNKTLSQQTCKSHVDTEKPYP 849
L + +S+T P SS+S+ P + + L +P
Sbjct: 7394 SQLSLSAMISPSPVSSTLPASSHSSSASVTSLLTPGQVKTTEVLDASA--------EPET 7445
Query: 850 ASIPELASTEMIKVKNHSVLQRTEKKVLPSPLELSVFSEGTDNKGNELPSAKLQDKQYIS 909
+S P L+ST + + V TEK + +V GT + G+E PS+ L D S
Sbjct: 7446 SSPPSLSSTSVEILATSEVTTDTEK--IHPFSNTAVTKVGTSSSGHESPSSVLPD----S 7499
Query: 910 SVDKAPFSEGSRNKTHKQGSTQSRLETSHTSK-SSEPSKSPDGIRNESRDSEISKRKTAE 968
KA + G+ + + S+T K SEP+ S E+ SE + A
Sbjct: 7500 ETTKATSAMGTISIMGDTSVSTLTPALSNTRKIQSEPASSLTTRLRETSTSE--ETSLAT 7557
Query: 969 QHSFGICKEKRARIEDDQSTRNIS----SSSPPEKEQPPREEPRVPPLKIQLSKIGPPFI 1024
+ + + K + T IS S S PE+ ++ I + I P I
Sbjct: 7558 EANTVLSKVSTGATTEVSRTEAISFSRTSMSGPEQSTMSQD--------ISIGTI--PRI 7607
Query: 1025 IKSQPVSKPESRASTSTSVSGGRNTGARTLADIKARAQQARAQREAAAAAAVAAAASIVS 1084
S ++ ES T T+ +G + + ++ + + + S
Sbjct: 7608 SASSVLT--ESAKMTITTQTGPSESTLESTLNLNTATTPSWVETHSIVIQGFPHPEMTTS 7665
Query: 1085 GAMGSPGEGGKTRTLAHIKEQTKAKLFAKHQARAHLFQTSKETRLPP-PLSSKEGPPNLE 1143
G G + + L H T+ +PP PL P
Sbjct: 7666 MGRGPGGVSWPSPPFVKETSPPSSPLSLPAVTSPHPVSTTFLAHIPPSPL-----PVTSL 7720
Query: 1144 VSSTPETKME--GSTGVIIVNPNCRSPSNKSAHLRETTTVLQQSLNPSKLPETATDLSVH 1201
++S P T + G++ P S S+ S E T + +TA +VH
Sbjct: 7721 LTSGPATTTDILGTS----TEPGTSSSSSLSTTSHERLTTYK---------DTAHTEAVH 7767
Query: 1202 SSDENIPVSHLSEKIVSSTSSENSSVPMLFNKNSVPVSVCSTAISGAIKEHPFVSSVDKS 1261
P ++ V++TSS S + +S +C+T+ G
Sbjct: 7768 ------PSTNTGGTNVATTSSGYKSQSSVLADSS---PMCTTSTMG-------------- 7804
Query: 1262 SVLMSVDSANTTISACNISMLKTIQGTDTPCIAIIPKCIESTPISATTEGSSISSSMDDK 1321
+T++ + L+T + ++ P ES+ T+ G+ +S+ +
Sbjct: 7805 ---------DTSVLTSTPAFLETRRIQTELASSLTPGLRESSGSEGTSSGTKMSTVLSK- 7854
Query: 1322 QLLISSSSASNLVSTQYTSVPTPSIGNNLPNLSTSSVLIPPMGINNRFPSEKIAIPGSE- 1380
+ + + + + TS+P P+ P++ST +V + F + + +E
Sbjct: 7855 ---VPTGATTEISKEDVTSIPGPAQSTISPDISTRTV--------SWFSTSPVMTESAEI 7903
Query: 1381 --EQATVSMGTTVRAALSCSDSVAVTDSLVAHPTVAM-FTGNMLTINSYDSPPKLS--AE 1435
T +G T + S D+ + T + H T++ F+ + ++ P +S +
Sbjct: 7904 TMNTHTSPLGATTQGT-STLDTSSTTSLTMTHSTISQGFSHSQMSTLMRRGPEDVSWMSP 7962
Query: 1436 SLDKNSGPRNRADNSGKPQQPPGGFAPAAINRSIPCKVI---VDHSTTLTSSLSLTVSVE 1492
L + + P S P +P+ ++ ++P + + ++ LTS L+ T +
Sbjct: 7963 PLLEKTRP------SFSLMSSPATTSPSPVSSTLPESISSSPLPVTSLLTSGLAKTTDML 8016
Query: 1493 SSEASLDLQGRPVRTEASVQPVACPQVSV-ISRPEPVANEGI--------DHSSTFIAAS 1543
+ + SV+ +A +V+ + P +N + H ST +
Sbjct: 8017 HKSSEPVTNSPANLSSTSVEILATSEVTTDTEKTHPSSNRTVTDVGTSSSGHESTSFVLA 8076
Query: 1544 AAKQDSKTLPATCTSLRE 1561
++ T P TS E
Sbjct: 8077 DSQTSKVTSPMVITSTME 8094
Score = 76.6 bits (187), Expect = 2e-13
Identities = 221/1001 (22%), Positives = 364/1001 (36%), Gaps = 122/1001 (12%)
Query: 523 SESPQEEMTVVIDQLEVCDSLIPSTSSMTHVSDTEHKESETA-----VETSTPKIKTGSS 577
+ESP + T VI L + + S S+MT ++ T T+ ++T T + G+
Sbjct: 6708 TESP-DISTEVIPSLPISLGITES-SNMTIITRTGPPLGSTSQGTFTLDTPTTSSRAGTH 6765
Query: 578 SLEGQ-FPNEGIAIDMELQSDPEE-QLSENACISETSFSSE-SPEGACTS------LPSP 628
S+ Q FP+ + M DPE + I +TSFSS P A TS LP
Sbjct: 6766 SMATQEFPHSEMTTVMN--KDPEILSWTIPPSIEKTSFSSSLMPSPAMTSPPVSSTLPKT 6823
Query: 629 GGETQSTSEESCTPASLETTFCSEVSSTENTDKYNQRNSTDENFHASLMSEISPISTSPE 688
T S TP+ + TT S T +ST + + + P
Sbjct: 6824 IHTTPSPMTSLLTPSLVMTTDTLGTSPEPTTSSPPNLSSTSHEILTTDEDTTAIEAMHPS 6883
Query: 689 ISEASLMSNLPLTS-----EASPVSNLPLTSETSPMSDLPLTSETSSVSSMLLTSETTFV 743
S A+ +N+ TS ++S +++ T T+PM T+ +SM ++SETT +
Sbjct: 6884 TSTAA--TNVETTSSGHGSQSSVLADSEKTKATAPMDTTSTMGHTTVSTSMSVSSETTKI 6941
Query: 744 SSLPLPSETSPISNSSINERMAHQQRKSPSVSEEPLSPQKDESSATAKPLGENLTSQQKN 803
S T + +SI++ + S +SE P + S G TS
Sbjct: 6942 KRESTYSLTPGLRETSISQNASFSTDTSIVLSEVPTGTTAEVSRTEVTSSGR--TSIPGP 6999
Query: 804 LSNTPEPIIMSSSSIAPEAFPS-EDLHNKTLSQQTCKSHVDTEKPYPASIPELASTEMIK 862
+T P I + + A P+ + T+ QT S ++ ST +
Sbjct: 7000 SQSTVLPEISTRTMTRLFASPTMTESAEMTIPTQTGPSGSTSQDTLTLD----TSTTKSQ 7055
Query: 863 VKNHSVLQR----TEKKVLPS--PLELSVFSEGTDNKGNELPS----AKLQDKQYISSVD 912
K HS L + +E L S P ++S S + + LPS ISS
Sbjct: 7056 AKTHSTLTQRFPHSEMTTLMSRGPGDMSWQSSPSLENPSSLPSLLSLPATTSPPPISSTL 7115
Query: 913 KAPFSEGSRNKTH-KQGSTQSRLETSHTSKSSEPSKSPDGIRNESRDSEISKRKTAEQHS 971
S T S + + HTS S P K T +
Sbjct: 7116 PVTISSSPLPVTSLLTSSPVTTTDMLHTSPELVTSSPPKLSHTSDERLTTGKDTTNTEAV 7175
Query: 972 FGICKEKRARIEDDQSTRNISSSSPPEKEQPPREEPR--VPPLKIQLSKIGPPFIIKSQP 1029
+ +E S SS+ + E P + I P +++
Sbjct: 7176 HPSTNTAASNVEIPSSGHESPSSALADSETSKATSPMFITSTQEDTTVAISTPHFLETSR 7235
Query: 1030 VSKPESRASTSTSVSGGRNTGARTLADIKARAQQARAQREAAAAAAVAAAASIVSGAMGS 1089
+ K ES +S S + R TG+ ++ A A + A + + S + S
Sbjct: 7236 IQK-ESISSLSPKL---RETGS-SVETSSAIETSAVLSEVSIGATTEISRTEVTSSSRTS 7290
Query: 1090 PGEGGKTRTLAHIKEQTKAKLFAKHQARAHLFQTSKETRLPPPLSSKEGPPNLEVSSTPE 1149
++ L I K F A + + +T+ PP S+ E L+ S+TP
Sbjct: 7291 ISGSAESTMLPEISTTRKIIKFPTSPILAESSEMTIKTQTSPPGSTSESTFTLDTSTTPS 7350
Query: 1150 TKMEGST----------GVIIVNPNCRSPSNKSAHLRETT-----TVLQQSLNPSKLPET 1194
+ ST ++ P S + ET+ L ++PS + T
Sbjct: 7351 LVITHSTMTQRLPHSEITTLVSRGAGDVPRPSSLPVEETSPPSSQLSLSAMISPSPVSST 7410
Query: 1195 ATDLSVHSSDENI-----PVSHLSEKIVSSTSSENSSVPMLFNKNSVPVSVCSTAISGAI 1249
S HSS ++ P + +++ +++ +S P + SV + S +
Sbjct: 7411 -LPASSHSSSASVTSLLTPGQVKTTEVLDASAEPETSSPPSLSSTSVEILATSEVTTDTE 7469
Query: 1250 KEHPFVSSV------------DKSSVLMSVDSANTTISACNISML-KTIQGTDTPCIAII 1296
K HPF ++ SSVL ++ T + IS++ T T TP ++
Sbjct: 7470 KIHPFSNTAVTKVGTSSSGHESPSSVLPDSETTKATSAMGTISIMGDTSVSTLTPALSNT 7529
Query: 1297 PKCIESTPISATTEGSSISSSMDDKQLLISSSSASNLVST--------------QYTSVP 1342
K I+S P S+ T +S+ ++ L +++ + VST TS+
Sbjct: 7530 RK-IQSEPASSLTTRLRETSTSEETSLATEANTVLSKVSTGATTEVSRTEAISFSRTSMS 7588
Query: 1343 TP---------SIGNNLPNLSTSSVLIPPMGINNRFPSEKIAIPGSEEQATVSMGTTVRA 1393
P SIG +P +S SSVL S K+ I + ++ +T+
Sbjct: 7589 GPEQSTMSQDISIG-TIPRISASSVLT---------ESAKMTITTQTGPSESTLESTLNL 7638
Query: 1394 ALSCSDSVAVTDSLV----AHPTVAMFTGNMLTINSYDSPP 1430
+ + S T S+V HP + G S+ SPP
Sbjct: 7639 NTATTPSWVETHSIVIQGFPHPEMTTSMGRGPGGVSWPSPP 7679
Score = 75.9 bits (185), Expect = 4e-13
Identities = 201/955 (21%), Positives = 354/955 (37%), Gaps = 159/955 (16%)
Query: 448 SVIQEEIAE-EVETSICECQDENHKTIPEFSEEAES--------LTNSHEEPQIAPPEDN 498
SV+ E A ++ T++ + +T P F +EA S +T P +
Sbjct: 4709 SVVTEGFAHSKITTAMNNDVKDVSQTNPPFQDEASSPSSQAPVLVTTLPSSVAFTPQWHS 4768
Query: 499 LESCVMMNDVL-----ETLPHIEVKIEGKSESPQEEMTVVIDQLEVCDSLIPSTSSMTHV 553
S V M+ VL +T ++ +E + SPQ M+ +D + V TS+ T
Sbjct: 4769 TSSPVSMSSVLTSSLVKTAGKVDTSLETVTSSPQS-MSNTLDDISV-------TSAATTD 4820
Query: 554 SDTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMELQSDPEEQLSENACIS---E 610
+T H T V + T S+ E + +P + S N S +
Sbjct: 4821 IETTHPSINTVVTN----VGTTGSAFESHST-------VSAYPEPSKVTSPNVTTSTMED 4869
Query: 611 TSFSSESPEGACTSLPSPGGETQSTSEESCTPASLETTFCSEVSSTENTDKYNQRNSTDE 670
T+ S P+ + T+ ET++TS S TP ET+ E++S+ T + T
Sbjct: 4870 TTISRSIPKSSKTTRT----ETETTS--SLTPKLRETSISQEITSSTETSTVPYKELTGA 4923
Query: 671 NFHASLMSEISPISTSPEISEASLMSNLPLTSEASPVSNLPLTSETSPMSDLPLTSETSS 730
S S STS + S +S T + +S P+ +E+ +++ +T++T
Sbjct: 4924 TTEVSRTDVTSSSSTSFPGPDQSTVSLDISTETNTRLSTSPIMTES---AEITITTQTGP 4980
Query: 731 VSSMLLTSETTFVSSLPLPSETSPISNSSINERMAHQQRKSPSVSEEPLSPQKDESSATA 790
+ TS+ TF PS T+P + I+ M H + + PQ + S T+
Sbjct: 4981 HGA---TSQDTFTMD---PSNTTP--QAGIHSAMTHGFSQLDVTTLMSRIPQ--DVSWTS 5030
Query: 791 KPLGENLTSQQKNLSNTPEPIIMSSSSIAPEAFPSEDLHNKTLSQQTCKSHVDTE----- 845
P + +S LS+ M++ S+ P + L + S T T+
Sbjct: 5031 PPSVDKTSSPSSFLSSP----AMTTPSLISSTLPEDKLSSPMTSLLTSGLVKITDILRTR 5086
Query: 846 -KPYPASIPELASTEMIKVKNHSVLQRTEKKVLPSPLELSVFSEGTDNKGNELPSAKLQD 904
+P +S+P +ST K+ S + K++ PS + + +N G+E S L D
Sbjct: 5087 LEPVTSSLPNFSSTS-DKILATSKDSKDTKEIFPS-INTEETNVKANNSGHESHSPALAD 5144
Query: 905 KQYISSVDKAPFSEGSRNKTHKQGSTQSRLETSHTSKSSEPSKSPDGIRNESRDSEISKR 964
S KA +TQ + T T PS S + S + I +
Sbjct: 5145 ----SETPKA--------------TTQMVITT--TVGDPAPSTSMP-VHGSSETTNIKRE 5183
Query: 965 KTAEQHSFGICKEKRARIEDDQSTRNISSSSPPEKEQPPREEPRVPPLKIQLSKIGPPFI 1024
T +P +E +E P F+
Sbjct: 5184 PT-------------------------YFLTPRLRETSTSQESSFP--------TDTSFL 5210
Query: 1025 IKSQPVSKPESRASTSTSVSGGRNTGARTLADIKARAQQARAQREAAAAAAVAAAASIVS 1084
+ P +ST + S +T + + R ++ +A ++
Sbjct: 5211 LSKVPTGTITEVSSTGVNSSSKISTPDHDKSTVPPDTFTGEIPRVFTSSIKTKSAEMTIT 5270
Query: 1085 GAMGSPGEGGKTRTLAHIKEQTKAKLFAKHQARAHLFQTSKETRLPPPLSSKEGPPNLEV 1144
SP E TL + T H F S+ T L GP N+
Sbjct: 5271 -TQASPPESASHSTLP-LDTSTTLSQGGTHSTVTQGFPYSEVTTL-----MGMGPGNVSW 5323
Query: 1145 SSTPETKMEGSTGVIIVNPNCRSPSNKSAHLRETTTVLQQSLNPSKLPETATDLSVHSSD 1204
+TP + S ++ +P SPS ++ QS+ S LP TA SV +
Sbjct: 5324 MTTPPVEETSSVSSLMSSPAMTSPS-------PVSSTSPQSIPSSPLPVTALPTSVLVTT 5376
Query: 1205 ENIPVSHLSEKIVSSTSSENS--------------SVPMLFNKNSVPVSVCSTAISGAIK 1250
++ + E + SS + +S + + + + V+ T+ SG
Sbjct: 5377 TDVLGTTSPESVTSSPPNLSSITHERPATYKDTAHTEAAMHHSTNTAVTNVGTSGSGHKS 5436
Query: 1251 EHPFV--SSVDKSSVLMSVDS--ANTTISACNISMLKTIQGTDTPCIAIIPKCIEST--- 1303
+ + S K++ LMS S +T++S ++ +T Q P ++ P+ ES+
Sbjct: 5437 QSSVLADSETSKATPLMSTTSTLGDTSVSTSTPNISQTNQIQTEPTASLSPRLRESSTSE 5496
Query: 1304 PISATTEGSSISSSMDDKQLLISSSSASNLVSTQYTSVPTPSIGNNLPNLSTSSV 1358
S+TTE ++ S + + +S + + T + + P+I P++ST +
Sbjct: 5497 KTSSTTETNTAFSYVPTGAITQASRTEISSSRTSISDLDRPTIA---PDISTGMI 5548
Score = 73.9 bits (180), Expect = 2e-12
Identities = 285/1448 (19%), Positives = 522/1448 (36%), Gaps = 248/1448 (17%)
Query: 373 TTGPNN----AGAQSSSSCGTSGLPVSAQTALAEQQ-----PKSMKSPASPEPGFCATLC 423
T P+N AG S+ + G S L V+ + Q P S+ +SP + L
Sbjct: 4990 TMDPSNTTPQAGIHSAMTHGFSQLDVTTLMSRIPQDVSWTSPPSVDKTSSPS----SFLS 5045
Query: 424 PMVEIPPKDIMAELESEDILIPEESVIQEEIAEEVETSICECQDENHKTIPEFSEEAESL 483
P I + L + + P S++ + + + + ++P FS ++ +
Sbjct: 5046 SPAMTTPSLISSTLPEDKLSSPMTSLLTSGLVKITDILRTRLEPVT-SSLPNFSSTSDKI 5104
Query: 484 T----NSHEEPQIAPPEDNLESCVMMNDVLETLPHIEVKIEGKSESPQEEMTVVIDQLEV 539
+S + +I P + E+ V N+ H + SE+P+ +VI
Sbjct: 5105 LATSKDSKDTKEIFPSINTEETNVKANNSGHE-SHSPALAD--SETPKATTQMVITT--T 5159
Query: 540 CDSLIPSTSSMTHVSDTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMELQSDPE 599
PSTS H S TP+++ S+S E FP + + ++ +
Sbjct: 5160 VGDPAPSTSMPVHGSSETTNIKREPTYFLTPRLRETSTSQESSFPTDTSFLLSKVPTGTI 5219
Query: 600 EQLS---------------ENACISETSFSSESPEGACTSLPSPGGETQSTSEESCTPAS 644
++S + + + +F+ E P +S+ + E T++ S ++
Sbjct: 5220 TEVSSTGVNSSSKISTPDHDKSTVPPDTFTGEIPRVFTSSIKTKSAEMTITTQASPPESA 5279
Query: 645 LETTFCSEVSSTENTDKYNQRNSTDENFHASLMSEISPIS-------TSPEISEASLMSN 697
+T + S+T + ++ + F S ++ + + T+P + E S +S+
Sbjct: 5280 SHSTLPLDTSTT--LSQGGTHSTVTQGFPYSEVTTLMGMGPGNVSWMTTPPVEETSSVSS 5337
Query: 698 L---PLTSEASPVSNLPLTSETSPMSDLPLTSETSSVSSMLLTSETTFVSSLPLPSETSP 754
L P + SPVS+ + ++ P S LP+T+ +SV L+T+ ++ P +SP
Sbjct: 5338 LMSSPAMTSPSPVSS--TSPQSIPSSPLPVTALPTSV---LVTTTDVLGTTSPESVTSSP 5392
Query: 755 ISNSSI-NERMAHQQRKSPSVSEEPLSPQKDESSATAKPLGENLTSQQKNLSN---TPEP 810
+ SSI +ER A K + +E + + + G SQ L++ +
Sbjct: 5393 PNLSSITHERPA--TYKDTAHTEAAMHHSTNTAVTNVGTSGSGHKSQSSVLADSETSKAT 5450
Query: 811 IIMSSSSIAPEAFPSEDLHNKTLSQQTCKSHVDTEKPYPASIPELASTEMIKVKNHSVLQ 870
+MS++S + S N + + Q + TE P + P L + + + +
Sbjct: 5451 PLMSTTSTLGDTSVSTSTPNISQTNQ-----IQTE-PTASLSPRLRESSTSEKTSSTTET 5504
Query: 871 RTEKKVLPSPLELSVFSEGTDNKGNELPSAKLQDKQYISSVDK---AP-FSEGSRNKTHK 926
T +P+ T E+ S++ IS +D+ AP S G +
Sbjct: 5505 NTAFSYVPT-------GAITQASRTEISSSRTS----ISDLDRPTIAPDISTGMITRLFT 5553
Query: 927 QGSTQSRLETSHTSKSSEPSKSPDGIRNESRDSEISKRKTAEQHSFGICKEK----RARI 982
E + T++++ P + GI + + + T S G + R+R
Sbjct: 5554 SPIMTKSAEMTVTTQTTTPGATSQGILPWDTSTTLFQGGTHSTVSQGFPHSEITTLRSRT 5613
Query: 983 EDDQSTRNISSSSPPEKEQPPREEPRVPPLKIQLSKIGPPFIIKSQPVSKPESRAS---- 1038
D S PP EE + S P + + P S P S
Sbjct: 5614 PGDVSWMT----------TPPVEETSSGFSLMSPSMTSPSPVSSTSPESIPSSPLPVTAL 5663
Query: 1039 ------TSTSVSGGRNTGARTLA--DIKARAQQARAQREAAAAAAVAAAASIVSGAMGSP 1090
T+T+V G + T + ++ + Q+ + A A+ + A+ +
Sbjct: 5664 LTSVLVTTTNVLGTTSPEPVTSSPPNLSSPTQERLTTYKDTAHTEAMHASMHTNTAVANV 5723
Query: 1091 GEGGKTRTLAHIKEQTKAKLFAKHQARAHLFQTSKETRLPPPLSSKEGPPNLEVS-STP- 1148
G + H++++ + S ++ P+ + VS STP
Sbjct: 5724 GTS-----------------ISGHESQSSVPADSHTSKATSPMGITFAMGDTSVSTSTPA 5766
Query: 1149 --ETKME-GSTGVIIVNPNCRSPSNKSAHLRETTTVLQQSLNPSKLPETATDLSVHSSDE 1205
ET+++ ST +I S + + ET+TVL S++P T T
Sbjct: 5767 FFETRIQTESTSSLIPGLRDTRTSEEINTVTETSTVL------SEVPTTTT--------- 5811
Query: 1206 NIPVSHLSEKIVSSTSSENSSVPMLFNKNSVPVSVCSTAISGAIKEHPFVSSVDKSSVLM 1265
+ +S V ++S S P +S ST + PFV+ + ++
Sbjct: 5812 ----TEVSRTEVITSSRTTISGP----DHSKMSPYISTETITRLSTFPFVTGSTEMAITN 5863
Query: 1266 SVDSANTTISA---CNISMLKTIQGTDTPCIAIIPKCIESTPISATTEGSSISSSMDDKQ 1322
T A + S + +GT +P P E+T +S +T+G
Sbjct: 5864 QTGPIGTISQATLTLDTSSTASWEGTHSPVTQRFPHSEETTTMSRSTKG----------- 5912
Query: 1323 LLISSSSASNLVSTQYTSVPTPSIGNNLPNLSTSSVLIPPMGINNRFPSEKIAIPG---S 1379
+S S ++ T S P P LP +++ S L ++ P+ + + S
Sbjct: 5913 --VSWQSPPSVEETSSPSSPVP-----LPAITSHSSLY--SAVSGSSPTSALPVTSLLTS 5963
Query: 1380 EEQATVSMGTTVRAALSCSDSVAVTDSLVAHPTVAMFTGNMLTINSYDSPPKL--SAESL 1437
+ T+ M T S VT SL P+ + F+G +LT + + + S +
Sbjct: 5964 GRRKTIDMLDT--------HSELVTSSL---PSASSFSGEILTSEASTNTETIHFSENTA 6012
Query: 1438 DKNSGPRN---RADNSGKPQQPPGGFAPAAINRSIPCKVIVDHSTTLTSSLSLTVSVESS 1494
+ N G N + +S P G P + S+ IV +T T T +V+
Sbjct: 6013 ETNMGTTNSMHKLHSSVSIHSQPSGHTPPKVTGSMMEDAIV---STSTPGSPETKNVDRD 6069
Query: 1495 EASLDLQGRPVRTEASVQPVACPQVSVISRPEPVANEGIDHSSTFIAASAAKQDSKTLPA 1554
S P+ E A S ++ +D ++ A D +PA
Sbjct: 6070 STS------PLTPELKEDSTALVMNSTTESNTVFSSVSLDAATEVSRAEVTYYDPTFMPA 6123
Query: 1555 TCTSLRELPLVPDKLNEPTAPSHNFAEQARGPAPFKSEADTTCSNQYNPSNRICWNDDGM 1614
+ S + + P+ + SH+ P T + Q PS G+
Sbjct: 6124 SAQSTKSPDISPE-----ASSSHS------NSPPLTISTHKTIATQTGPS--------GV 6164
Query: 1615 RSTGQ------PLVTHSG--SSKQKEYLEQSCPKAIKTEHANYLNVSELHPRN------- 1659
S GQ + T +G S++ +++++ + + + L S
Sbjct: 6165 TSLGQLTLDTSTIATSAGTPSARTQDFVDSETTSVMNNDLNDVLKTSPFSAEEANSLSSQ 6224
Query: 1660 ---LVTNVALPVKSELHEADKGFRMDTEDFPGPELPPPAAEGASSVQQTQNMKASTSSPM 1716
LVT PV S L E + P P L A N++ T SP
Sbjct: 6225 APLLVTTSPSPVTSTLQEHSTSSLVSVTSVPTPTL-------AKITDMDTNLEPVTRSPQ 6277
Query: 1717 EEAISLAT 1724
+LAT
Sbjct: 6278 NLRNTLAT 6285
Score = 73.6 bits (179), Expect = 2e-12
Identities = 237/1121 (21%), Positives = 409/1121 (36%), Gaps = 126/1121 (11%)
Query: 544 IPSTSSMTHVSDTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMELQSDPEEQLS 603
IP+TS + ++ H S TAV K++T SS E + + D E
Sbjct: 9793 IPATSEIMTDTEKIHPSSNTAVA----KVRTSSSVHES---HSSVLADSETTITIPSMGI 9845
Query: 604 ENACISETSFSSESPEGACTSLPSPGGETQSTSEESCTPASLETTFCSEVSSTENTDKYN 663
+A T F+S +P T+ T S TP ET+ E +S T
Sbjct: 9846 TSAVDDTTVFTSNPAFSETRRIP-----TEPTF--SLTPGFRETSTSEETTSITETSAVL 9898
Query: 664 QRNSTDENFHASLMSEISPISTSPEISEASLMSNLPLTSEASPVSNLPLTSETSPMSDLP 723
T S+ +S S+ S MS +T + +S+ + SE++ M+
Sbjct: 9899 YGVPTSATTEVSMTEIMSSNRIHIPDSDQSTMSPDIITEVITRLSSSSMMSESTQMT--- 9955
Query: 724 LTSETSSVSSMLLTSETTFVSSLPLPSETSPIS--NSSINERMAHQQRKSPSVSEEPLSP 781
+T++ SS + T S+L L + T+P++ +S++ R H + + +S P +P
Sbjct: 9956 ITTQKSSPGA-------TAQSTLTLATTTAPLARTHSTVPPRFLHSEMTT-LMSRSPENP 10007
Query: 782 QKDESSATAKPLGENLTSQQKNLSNTPEPIIMSSSSIAPEAFPSEDLHNKTLSQQTCKSH 841
S K TS +L + P S SS P++ PS +L
Sbjct: 10008 SWKSSLFVEK------TSSSSSLLSLPVTTSPSVSSTLPQSIPSSSFSVTSLLTPGMVKT 10061
Query: 842 VDTE-KPYPASIPELASTEMIKVKNHSVLQRTEKKVLPSPLELSVFSEGTDNKGNELPSA 900
DT +P + P L+ T + + V TE K+ PS ++V + GT + G+EL S+
Sbjct: 10062 TDTSTEPGTSLSPNLSGTSVEILAASEVTTDTE-KIHPSS-SMAVTNVGTTSSGHELYSS 10119
Query: 901 KLQDKQYISSVDKAPFSEG---SRNKTHKQGSTQSRLETSHTSKSSEP-SKSPDGIRNES 956
S KA + G S +T S + ET T +EP S G R +
Sbjct: 10120 ----VSIHSEPSKATYPVGTPSSMAETSISTSMPANFET--TGFEAEPFSHLTSGFRKTN 10173
Query: 957 RDSEISKRKTAEQHSFGICKEKRARIEDDQSTRNISSSSPPEKEQPPREEPRVPPLKIQL 1016
+ S S + T SS+ + PP + P+ I
Sbjct: 10174 MSLDTSSVTPTNTPS----SPGSTHLLQSSKTDFTSSAKTSSPDWPPASQYTEIPVDIIT 10229
Query: 1017 SKIGPPFIIKSQPV-SKPESRASTSTSVSGGR-NTGARTLADIKARAQQARAQREAAAAA 1074
P I +S + S PESR + S + S +T A+ + + EA +
Sbjct: 10230 PFNASPSITESTGITSFPESRFTMSVTESTHHLSTDLLPSAETISTGTVMPSLSEAMTSF 10289
Query: 1075 AVAAAASIVSGAMGSP----GEGGKTRTLAHIKEQTKAKLFAKHQARAHLFQTSKETRLP 1130
A +SG+ GSP G TL+ I E + + F T+ + +P
Sbjct: 10290 ATTGVPRAISGS-GSPFSRTESGPGDATLSTIAESLPSSTPVPFSSST--FTTTDSSTIP 10346
Query: 1131 ---PPLSSKEGPPNLEVS-STPETKMEGSTGVIIVNPNCRSPS-NKSAHLRETTTVLQQS 1185
SS P ++ S T + EG ++ P S+ + +T
Sbjct: 10347 ALHEITSSSATPYRVDTSLGTESSTTEGRLVMVSTLDTSSQPGRTSSSPILDTRMTESVE 10406
Query: 1186 LNPSKLPETATDLSVHSSDENIPVSHLSEKIVSSTSSENSSVPMLFNKNSVPVSVCSTAI 1245
L LS + + + H++ KI + + + P+ + S +
Sbjct: 10407 LGTVTSAYQVPSLSTRLTRTDGIMEHIT-KIPNEAAHRGTIRPVKGPQTSTSPASPKGLH 10465
Query: 1246 SGAIKEHPFVSSVDKSSVLMSVDSANTTISACNISMLKTIQGTDTPCIAIIPKCIESTPI 1305
+G K ++ K++ ++ T++ S+ GT TP A + + + P
Sbjct: 10466 TGGTKRMETTTTALKTTTTALKTTSRATLTT---SVYTPTLGTLTPLNASM-QMASTIPT 10521
Query: 1306 SATTEGSSISSSMDDKQLLISSSSASNLVSTQYTSVP--TPSIGNNLPNLSTSSVLIPPM 1363
+ + + +SS A++L + T++P TPS+ N T++ L+
Sbjct: 10522 EMMITTPYVFPDVPE----TTSSLATSLGAETSTALPRTTPSVFNR--ESETTASLVSRS 10575
Query: 1364 GINNRFPSEKIAIPGSEEQATVSMGTTVRAALSCSDSVAVTDSLVAHPTVAMFTGNMLTI 1423
G + + + SE T S V HP + T + T
Sbjct: 10576 GAERSPVIQTLDVSSSEPDTTASW--------------------VIHPAETIPTVSKTTP 10615
Query: 1424 NSYDSPPKLSAESLDKNSGPRNRADNSGKPQQPPGGFAPAAINRSIPCKVIVDHSTTLTS 1483
N + S +L S ++ + AD S P +P+ ++ P V + + T T+
Sbjct: 10616 NFFHS--ELDTVS---STATSHGADVS---SAIPTNISPSELDALTPL-VTISGTDTSTT 10666
Query: 1484 SLSLTVSVESSEASLDLQGRPVRTEASV----------QPVACPQVSV-------ISRPE 1526
+LT S +E P T +++ + A P ++ + P
Sbjct: 10667 FPTLTKSPHETETRTTWLTHPAETSSTIPRTIPNFSHHESDATPSIATSPGAETSSAIPI 10726
Query: 1527 PVANEGIDHSSTFIAASAAKQDSKTLPATCTSLRELPLVPDKLNEPTA-PSHNFAEQARG 1585
+ G + T S+ + T+P S E + + P A S
Sbjct: 10727 MTVSPGAEDLVTSQVTSSGTDRNMTIPTLTLSPGEPKTIASLVTHPEAQTSSAIPTSTIS 10786
Query: 1586 PAPFK--SEADTTCSNQYNPSNRICWNDDGMRSTGQPLVTH 1624
PA + + T+ + + + +NR N G +T LVTH
Sbjct: 10787 PAVSRLVTSMVTSLAAKTSTTNRALTNSPGEPATTVSLVTH 10827
Score = 65.9 bits (159), Expect = 4e-10
Identities = 248/1319 (18%), Positives = 463/1319 (35%), Gaps = 181/1319 (13%)
Query: 556 TEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMELQSDPEEQLSENACISETSFSS 615
T H +AV S+P +SL + IDM D +L ++ S +SFS
Sbjct: 5937 TSHSSLYSAVSGSSPTSALPVTSLLTSGRRK--TIDM---LDTHSELVTSSLPSASSFSG 5991
Query: 616 ESPEGACTSLPSPGGET----QSTSEESCTPASLETTFCSEVSSTENTDKYNQRNSTDEN 671
E TS S ET ++T+E + + S VS + T
Sbjct: 5992 E----ILTSEASTNTETIHFSENTAETNMGTTNSMHKLHSSVSIHSQPSGHTPPKVTGSM 6047
Query: 672 FHASLMSEISPISTSPEISEASLMSNLPLTSEASPVSNLPLTSETSPMSDLPLTSETSSV 731
+++S +P SPE S PLT E S + + T+ S+ +S +
Sbjct: 6048 MEDAIVSTSTP--GSPETKNVDRDSTSPLTPELKEDSTALVMNSTTE-SNTVFSSVSLDA 6104
Query: 732 SSMLLTSETTFVSSLPLPSETSPISNSSINERMAHQQRKSPSVS---EEPLSPQKDESSA 788
++ + +E T+ +P+ + I+ + SP ++ + ++ Q S
Sbjct: 6105 ATEVSRAEVTYYDPTFMPASAQSTKSPDISPEASSSHSNSPPLTISTHKTIATQTGPSGV 6164
Query: 789 TAKPLGENLTSQQKNLSNTPEPIIMSSSSIAPEAFPSEDLHN------------KTLSQQ 836
T+ TS + TP + + DL++ +LS Q
Sbjct: 6165 TSLGQLTLDTSTIATSAGTPSARTQDFVDSETTSVMNNDLNDVLKTSPFSAEEANSLSSQ 6224
Query: 837 TCKSHVDTEKPYPASIPELASTEMIKVKNHSVLQRTEKKVLPSPLELSVFSEGTDNKGNE 896
+ P +++ E +++ ++ V SV T K+ L + N N
Sbjct: 6225 APLLVTTSPSPVTSTLQEHSTSSLVSVT--SVPTPTLAKITDMDTNLEPVTRSPQNLRNT 6282
Query: 897 LPSAKLQDKQYIS--SVDKAPFSEGSRNKTHKQGSTQSRLETSHTSKSSE--PSKSPDGI 952
L +++ + S++ A + G+ + ++ T S + + S+ S S D I
Sbjct: 6283 LATSEATTDTHTMHPSINTAVANVGTTSSPNEFYFTVSPDSDPYKATSAVVITSTSGDSI 6342
Query: 953 RNESRDSEISKRKTAEQHSFGICKEKRARIEDDQSTRNISSSSPPEKEQPPREEPRVPPL 1012
+ S + +K + +F + R+ + +++ I SSS
Sbjct: 6343 VSTSMPRSSAMKKIESETTFSLI----FRLRETSTSQKIGSSSDTS-------------- 6384
Query: 1013 KIQLSKIGPPFIIKSQPVSKPESRASTSTSVSGGR------NTGARTLADIKARAQQARA 1066
+ F + VS+ E +S+ TS+ G +T R++ + A ++
Sbjct: 6385 ----TVFDKAFTAATTEVSRTELTSSSRTSIQGTEKPTMSPDTSTRSVTMLSTFAGLTKS 6440
Query: 1067 QREAAAAAAVAAAASIVSGAMGSPGEGGKTRTLAHIKEQTKAKLFAKHQARAHLFQT--- 1123
+ A +G + +G T + Q H A H F
Sbjct: 6441 EERTIATQ---------TGPHRATSQGTLTWDTSITTSQA-----GTHSAMTHGFSQLDL 6486
Query: 1124 SKETRLPPPLSSKEGPPNLEVSSTPETKME-----GSTGVIIVNPNCR--SP----SNKS 1172
S T P S PP++E +S+ + + + V P R SP S +
Sbjct: 6487 STLTSRVPEYISGTSPPSVEKTSSSSSLLSLPAITSPSPVPTTLPESRPSSPVHLTSLPT 6546
Query: 1173 AHLRETTTVLQQ--SLNPS------KLPETATDLSVHSSDENIPVSHLSEKIVSSTSSEN 1224
+ L +TT +L SL P+ K+P T+ D+ +++ P ++++ V +T+SE
Sbjct: 6547 SGLVKTTDMLASVASLPPNLGSTSHKIPTTSEDIK--DTEKMYPSTNIAVTNVGTTTSEK 6604
Query: 1225 SSVPMLFNKNSVPVSVCSTAISGAIKEHPFVSSVDKSSVLMSVDSANTTISACNISMLKT 1284
S + + P S I++ +S+ SS + ++ +T S+
Sbjct: 6605 ESYSSVPAYSEPPKVTSPMVTSFNIRDTIVSTSMPGSSEITRIEMEST------FSLAHG 6658
Query: 1285 IQGTDTPCIAIIPKCIESTPISATTEGSSISSSMDDKQLLISSSSASNLVSTQYTSVPTP 1344
++GT T I+ +TE S++ + + +S + + S++ TS+P P
Sbjct: 6659 LKGTSTSQDPIV-----------STEKSAVLHKLTTGA---TETSRTEVASSRRTSIPGP 6704
Query: 1345 SIGNNLPNLSTSSVLIPPMGINNRFPSEKIAIP------GSEEQATVSMGTTVRAALSCS 1398
P++ST + P+ + S I GS Q T ++ T ++ + +
Sbjct: 6705 DHSTESPDISTEVIPSLPISLGITESSNMTIITRTGPPLGSTSQGTFTLDTPTTSSRAGT 6764
Query: 1399 DSVAVTDSLVAHPTVAMFTGNMLTINSYDSPPKLSAESLDKNSGPRNRADNSGKPQQPPG 1458
S+A + H + I S+ PP S++K S + + P
Sbjct: 6765 HSMATQE--FPHSEMTTVMNKDPEILSWTIPP-----SIEKTSFSSSLMPSPAMTSPPVS 6817
Query: 1459 GFAPAAINRS-IPCKVIVDHSTTLTSSLSLTVSVE---SSEASLDLQGRPV-RTEASVQP 1513
P I+ + P ++ S +T+ +L S E SS +L + T+
Sbjct: 6818 STLPKTIHTTPSPMTSLLTPSLVMTTD-TLGTSPEPTTSSPPNLSSTSHEILTTDEDTTA 6876
Query: 1514 VACPQVSVISRPEPVANEGIDHSSTFIAASAAKQDSKTLPATCTSLRELPLVPDKLNEPT 1573
+ S + V H S + +++ T P TS V ++ +
Sbjct: 6877 IEAMHPSTSTAATNVETTSSGHGSQSSVLADSEKTKATAPMDTTSTMGHTTVSTSMSVSS 6936
Query: 1574 APSHNFAEQARGPAPFKSEADTTCSNQYNPSNRICWNDDGMRSTGQPLVTHSGSSKQKEY 1633
+ E P E + + ++ I ++ +T + T SS +
Sbjct: 6937 ETTKIKRESTYSLTPGLRETSISQNASFSTDTSIVLSEVPTGTTAEVSRTEVTSSGRTSI 6996
Query: 1634 LEQSCPKAIKTEHANYLNVSELHPRNLVTNVALPVKSELHEADKGFRMDTEDFPGPELPP 1693
S + E+ R + A P +E E +P
Sbjct: 6997 PGPSQSTVL----------PEISTRTMTRLFASPTMTESAEM--------------TIPT 7032
Query: 1694 PAAEGASSVQQTQNMKASTSSPMEEAISLATD---------ALKRVPGAGSSGCRLSSVE 1744
S+ Q T + ST+ + S T + R PG S SS
Sbjct: 7033 QTGPSGSTSQDTLTLDTSTTKSQAKTHSTLTQRFPHSEMTTLMSRGPGDMS---WQSSPS 7089
Query: 1745 ANNPLVTQLLQGNLPLEKVLPQPRLGAKLEINRLPLPLQTTSVGKTAPERNVEIPPSSP 1803
NP L L L P + + L + PL TS+ ++P ++ +SP
Sbjct: 7090 LENP---SSLPSLLSLPATTSPPPISSTLPVTISSSPLPVTSLLTSSPVTTTDMLHTSP 7145
Score = 63.5 bits (153), Expect = 2e-09
Identities = 228/1155 (19%), Positives = 405/1155 (35%), Gaps = 188/1155 (16%)
Query: 483 LTNSHEEPQIAPPEDNLESCVMMNDVLETLPHIEVKIEGKSESPQEEMTVVIDQLEVCDS 542
LT + +A D+ + +D L T+P + + S +V+ + D
Sbjct: 2652 LTATEPTSSLATSFDSTPLVTIASDSLGTVPETTLTMSETSNGD----ALVLKTVSNPDR 2707
Query: 543 LIPSTSSMTHVSDTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMELQSDPEEQL 602
IP + H S + + P+ T S+ L +
Sbjct: 2708 SIPGITIQGVTESPLHPSSTSPSKIVAPRNTTYEGSITVALSTLPAGTTGSLVFSQSSEN 2767
Query: 603 SENACISETSFSSE---------SPEGACTSLPSPGGETQSTSEESCTPASL-----ETT 648
SE + ++S E +G +S G T ST ++ + L E T
Sbjct: 2768 SETTALVDSSAGLERASVMPLTTGSQGMASSGGIRSGSTHSTGTKTFSSLPLTMNPGEVT 2827
Query: 649 FCSEVSSTENTDKYNQRNS----TDENFHASLMSEISPISTSPEISEASLMSNLP----- 699
SE+++ T + + + L++ +S S+SP + ASL + P
Sbjct: 2828 AMSEITTNRLTATQSTAPKGIPVKPTSAESGLLTPVSA-SSSPSKAFASLTTAPPTWGIP 2886
Query: 700 ---LTSEASPVSNLPLTSETSPMSDLPLT----SETSSVSS-------------MLLTSE 739
LT E S V +L S + P L S+ S+ SS M+ +++
Sbjct: 2887 QSTLTFEFSEVPSLDTKSASLPTPGQSLNTIPDSDASTASSSLSKSPEKNPRARMMTSTK 2946
Query: 740 TTFVSSLPLPSETSPISNSSINERMAHQQRKSPSVSEEPL---------SPQKDESSATA 790
SS T S+ H+ R S + +P P K S+ T+
Sbjct: 2947 AISASSFQSTGFTETPEGSASPSMAGHEPRVPTSGTGDPRYASESMSYPDPSKASSAMTS 3006
Query: 791 KPLGENLTS-----QQKNLSNTPEPIIMSSSSIAPEAFPSEDLHNKT--------LSQQT 837
L LT+ Q ++ PI +S+ P+ KT Q
Sbjct: 3007 TSLASKLTTLFSTGQAARSGSSSSPISLSTEKETSFLSPTASTSRKTSLFLGPSMARQPN 3066
Query: 838 CKSHVDTEKPY--PASI--------PELASTEMIKVKNHSVLQRTEKKVLPS--PLELSV 885
H+ T P S PEL S++ I + + + PS P L
Sbjct: 3067 ILVHLQTSALTLSPTSTLNMSQEEPPELTSSQTIAEEEGTTAETQTLTFTPSETPTSLLP 3126
Query: 886 FSEGTDN--KGNELPSAKLQDKQYISSVDKAPFSEGSRNKTHKQGSTQSRLETSHTSKSS 943
S T+ + P + ++G+ T K S ++ ++ + +
Sbjct: 3127 VSSPTEPTARRKSSPETWASSISVPAKTSLVETTDGTLVTTIKMSSQAAQGNSTWPAPAE 3186
Query: 944 EPSKSPDGIRNESRDSEISKRKTAEQHSFGICKEKRARIEDD-QSTRNISSSSPPEKEQP 1002
E SP G S + + + I K I + +ST S PE P
Sbjct: 3187 ETGSSPAGTSPGSPEMSTTLK---------IMSSKEPSISPEIRSTVRNSPWKTPETTVP 3237
Query: 1003 PREEPRVPPLKIQLSKIGPPFIIKSQPVSKPESRASTSTSVSGGRNTGARTLADIKARAQ 1062
E V P+ +Q + +G S STS+S + T + K+ +
Sbjct: 3238 M--ETTVEPVTLQSTALG-----------------SGSTSIS---HLPTGTTSPTKSPTE 3275
Query: 1063 QARA-QREAAAAAAVAAAASIVSGAMGSPGEGGKTRTLAHIKEQTKAKLFAKHQARAHLF 1121
A +R + + + A ++ SG G + T + ++ T + Q +
Sbjct: 3276 NMLATERVSLSPSPPEAWTNLYSGTPGGTRQSLATMSSVSLESPTARSITGTGQQSS--- 3332
Query: 1122 QTSKETRLPPPLSSKEGPPNLEVSSTPETKMEGSTGVIIVNPNCRSPSNKSAHLRETTTV 1181
P L SK +E S GSTG + + L ++ +
Sbjct: 3333 ---------PELVSKT--TGMEFSM-----WHGSTG--------GTTGDTHVSLSTSSNI 3368
Query: 1182 LQQSLNPSKLPETATDLSVHSSDE-----NIPVSHLSEKIVSSTSSENSSVPMLFNKNS- 1235
L+ + + TD S H ++ IP + L+ KI+++ + SV ++ S
Sbjct: 3369 LEDPVTSPNSVSSLTDKSKHKTETWVSTTAIPSTVLNNKIMAAEQQTSRSVDEAYSSTSS 3428
Query: 1236 ----VPVSVCSTAISGAIKEHPFVSSVDKSSVLMSVDSANTTI-SACNISMLKTIQGTDT 1290
S + S + +++S +++ L+S+ S + I S N S KT +
Sbjct: 3429 WSDQTSGSDITLGASPDVTNTLYITSTAQTTSLVSLPSGDQGITSLTNPSGGKTSSASSV 3488
Query: 1291 PCIAIIPKCIESTPISATTEGSSISSSMDDKQLLISSSSASNLVSTQYTSVPTPSIGNNL 1350
+I +E+ + + S I+ + L +SS + + T+ PTP I +
Sbjct: 3489 TSPSI---GLETLRANVSAVKSDIAPTAGH---LSQTSSPAEVSILDVTTAPTPGISTTI 3542
Query: 1351 PNLSTSSVLI----PPMGINNRFPSEKIAIPGSEEQATVSMGTTVRAALSCSDSVAVTDS 1406
+ T+S+ P +G+ S + P +E + T + + ++ + SDS VTD
Sbjct: 3543 TTMGTNSISTTTPNPEVGM-----STMDSTPATERRTTSTEHPSTWSSTAASDSWTVTD- 3596
Query: 1407 LVAHPTVAMFTGNMLTINSYDSPPKLSAESLDKNSGPRNRADNSGKPQQPPGGFAPAAIN 1466
+ ++ VA G + T+++ + S+ LD S P R G P A A
Sbjct: 3597 MTSNLKVARSPGTISTMHT--TSFLASSTELDSMSTPHGRITVIGTSLVTPSSDASAV-- 3652
Query: 1467 RSIPCKVIVDHSTTLTSSLSLTVSVESSEASLDLQGRPVRTEASVQPV---ACPQVSVIS 1523
+ T TS +L+ S ++ + R R SV + + S +
Sbjct: 3653 ----------KTETSTSERTLSPSDTTASTPISTFSRVQRMSISVPDILSTSWTPSSTEA 3702
Query: 1524 RPEPVANEGIDHSST 1538
PV+ DH+ST
Sbjct: 3703 EDVPVSMVSTDHAST 3717
Score = 63.2 bits (152), Expect = 3e-09
Identities = 281/1344 (20%), Positives = 473/1344 (35%), Gaps = 227/1344 (16%)
Query: 364 MSREESVKLTTGPNNAGAQSSSSCGTSGLPVSAQTALAEQQPKSM-KSPASPEPGFCATL 422
MSR T P SSS TS LP++ T+L+ + SP+SP P L
Sbjct: 9706 MSRGPESLSWTSPRFVETTRSSSSLTS-LPLT--TSLSPVSSTLLDSSPSSPLPVTSLIL 9762
Query: 423 CPMVEI---------PPKDIMAELESEDILIPEESVIQ---EEIAEEVETSICECQDENH 470
+V+ P L S + IP S I E+I T++ + + +
Sbjct: 9763 PGLVKTTEVLDTSSEPKTSSSPNLSSTSVEIPATSEIMTDTEKIHPSSNTAVAKVRTSSS 9822
Query: 471 KTIPEFSEEAESLTNSHEEPQIAPPEDNLESCVMMNDVLETLPHIEVKIEGKSESPQEEM 530
E+ S + E I P + S V V + P ++ E
Sbjct: 9823 V------HESHSSVLADSETTITIPSMGITSAVDDTTVFTSNPAFS-----ETRRIPTEP 9871
Query: 531 TVVIDQLEVCDSLIPSTSSMTHVSDTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAI 590
T SL P + +T +AV P T S+ + I I
Sbjct: 9872 TF---------SLTPGFRETSTSEETTSITETSAVLYGVPTSATTEVSMTEIMSSNRIHI 9922
Query: 591 DMELQSDPEEQLSENAC--ISETSFSSESPEGACTSLPS-PGGETQSTSEESCTPASLET 647
QS + +S +S SES + T+ S PG QST + T A L
Sbjct: 9923 PDSDQSTMSPDIITEVITRLSSSSMMSESTQMTITTQKSSPGATAQSTLTLATTTAPLAR 9982
Query: 648 TFCSEVSSTENTDKYNQRNSTDEN--FHASLMSEIS---------PISTSPEISEASLMS 696
T + +++ + + EN + +SL E + P++TSP +S ++L
Sbjct: 9983 THSTVPPRFLHSEMTTLMSRSPENPSWKSSLFVEKTSSSSSLLSLPVTTSPSVS-STLPQ 10041
Query: 697 NLPLTSEASPVSNLPLTSETSPMSDLPLTSETSSVSS----MLLTSETTFVSSLPLPSET 752
++P +S + P +T+ S P TS + ++S +L SE T + PS +
Sbjct: 10042 SIPSSSFSVTSLLTPGMVKTTDTSTEPGTSLSPNLSGTSVEILAASEVTTDTEKIHPSSS 10101
Query: 753 SPISNSSINERMAHQQRKSPSVSEEPLS---PQKDESSATAKPLGENLTSQQKNLSNTPE 809
++N H+ S S+ EP P SS + ++ + + E
Sbjct: 10102 MAVTNVGTTSS-GHELYSSVSIHSEPSKATYPVGTPSSMAETSISTSMPANFETTGFEAE 10160
Query: 810 P------------IIMSSSSIAPEAFPSE--DLHNKTLSQQTCKSHVDTEKPY--PASIP 853
P + + +SS+ P PS H S+ S T P PAS
Sbjct: 10161 PFSHLTSGFRKTNMSLDTSSVTPTNTPSSPGSTHLLQSSKTDFTSSAKTSSPDWPPASQY 10220
Query: 854 ELASTEMIKVKNHS--VLQRTEKKVLPSPLELSVFSEGTDNKGNEL-PSAK-LQDKQYIS 909
++I N S + + T P +E T + +L PSA+ + +
Sbjct: 10221 TEIPVDIITPFNASPSITESTGITSFPESRFTMSVTESTHHLSTDLLPSAETISTGTVMP 10280
Query: 910 SVDKAPFS---EGSRNKTHKQGSTQSRLE------TSHTSKSSEPSKSPDGIRNESRDSE 960
S+ +A S G GS SR E T T S PS +P + + +
Sbjct: 10281 SLSEAMTSFATTGVPRAISGSGSPFSRTESGPGDATLSTIAESLPSSTPVPFSSSTFTTT 10340
Query: 961 ISKRKTAEQHSFGICKEKRARIEDDQSTRNIS-------------SSSPPEKEQPPREEP 1007
S A H R++ T + + SS P P +
Sbjct: 10341 DSSTIPA-LHEITSSSATPYRVDTSLGTESSTTEGRLVMVSTLDTSSQPGRTSSSPILDT 10399
Query: 1008 RVPPLKIQLSKIGPPFIIKSQPVSKPESRASTSTSVSGGRNTGARTLADIKARAQQARAQ 1067
R+ ++L + + + S ST + + G + + A R
Sbjct: 10400 RMTE-SVELGTVTSAYQVPS---------LSTRLTRTDGIMEHITKIPNEAAHRGTIRPV 10449
Query: 1068 REAAAAAAVAAAASIVSGAMGSPGEGGKTRTLAHIKEQTKAKLFAKHQARAHLFQTSKET 1127
+ + + A+ + +G G T +K T A K +RA L T
Sbjct: 10450 KGPQTSTSPASPKGLHTG-----GTKRMETTTTALKTTTTA---LKTTSRATL-----TT 10496
Query: 1128 RLPPPLSSKEGPPN--LEVSSTPETKMEGSTGVIIVNPNCRSPSNKSAHLRETTTVLQQS 1185
+ P P N ++++ST T+M +T + + + S ++ ET+T L ++
Sbjct: 10497 SVYTPTLGTLTPLNASMQMASTIPTEMMITTPYVFPDVPETTSSLATSLGAETSTALPRT 10556
Query: 1186 LNPS---KLPETATDLSVHSSDENIPVSHLSEKIVSSTSSENSSVPMLFNKNSVPV---- 1238
PS + ET L S E PV + VSS+ + ++ ++ ++P
Sbjct: 10557 -TPSVFNRESETTASLVSRSGAERSPVIQTLD--VSSSEPDTTASWVIHPAETIPTVSKT 10613
Query: 1239 ----------SVCSTA------ISGAIKEHPFVSSVDKSSVLMSVDSANTTISACNISML 1282
+V STA +S AI + S +D + L+++ +T+ + ++
Sbjct: 10614 TPNFFHSELDTVSSTATSHGADVSSAIPTNISPSELDALTPLVTISGTDTSTTFPTLTKS 10673
Query: 1283 KTIQGTDTPCI-------AIIPKCI--------ESTPISATTEGSSISSSMDDKQLLISS 1327
T T + + IP+ I ++TP AT+ G+ SS++ ++ S
Sbjct: 10674 PHETETRTTWLTHPAETSSTIPRTIPNFSHHESDATPSIATSPGAETSSAIP---IMTVS 10730
Query: 1328 SSASNLVSTQYTS--------VPTPSIGNNLPNLSTSSVLIPPMGINNRFPSEKIA---- 1375
A +LV++Q TS +PT ++ P S V P ++ P+ I+
Sbjct: 10731 PGAEDLVTSQVTSSGTDRNMTIPTLTLSPGEPKTIASLVTHPEAQTSSAIPTSTISPAVS 10790
Query: 1376 --IPGSEEQATVSMGTTVRAALSCSDSVAVTDSLVAHP-----TVAMFTGNMLTINSYDS 1428
+ TT RA + A T SLV HP TV T S +
Sbjct: 10791 RLVTSMVTSLAAKTSTTNRALTNSPGEPATTVSLVTHPAQTSPTVPWTTSIFFHSKSDTT 10850
Query: 1429 PPKLSAESLDKNSGPRNRADNSGKPQQPPGGFAP------AAINRSIPCKVIVDHSTTLT 1482
P ++ + +S ++ + PG P A I+ +IP + T
Sbjct: 10851 PSMTTSHGAESSSAVPTPTVST----EVPGVVTPLVTSSRAVISTTIPILTLSPGEPETT 10906
Query: 1483 SSLSLTVSVESSEASLDLQGRPVRTEASVQPVACPQVSVISRPEPVANEGIDHSSTFIAA 1542
S++ + E+S A P P + G+ T +
Sbjct: 10907 PSMATSHGEEASSAI---------------------------PTPTVSPGVPGVVTSLVT 10939
Query: 1543 SAAKQDSKTLPATCTSLRELPLVP 1566
S+ S T+P SL E P
Sbjct: 10940 SSRAVTSTTIPILTFSLGEPETTP 10963
Score = 61.2 bits (147), Expect = 1e-08
Identities = 241/1236 (19%), Positives = 450/1236 (36%), Gaps = 184/1236 (14%)
Query: 377 NNAGAQSSSSCGTSGLPVSAQTALAEQQPK-SMKSPASPEPGFCATLCPM--VEIPPKDI 433
++A + S TS PVS+ L E P S+ + PG T M P
Sbjct: 8264 SSASSLLSLPATTSPSPVSS--TLVEDFPSASLPVTSLLNPGLVITTDRMGISREPGTSS 8321
Query: 434 MAELES---EDILIPEESVIQEEIAEEVETSICECQDENHKTIPEFSEEAESLTNSHEEP 490
+ L S E + E++V E++ T++ N +T E S+ + E P
Sbjct: 8322 TSNLSSTSHERLTTLEDTVDTEDMQPSTHTAVT-----NVRTSISGHESQSSVLSDSETP 8376
Query: 491 QIAPPEDNLESCVMMNDVLETLPHIE---VKIEGKSESPQEEMTVVIDQLEVCDSLIPST 547
+ P + + + T E ++IE P +T + + + + +T
Sbjct: 8377 KATSPMGTTYTMGETSVSISTSDFFETSRIQIE-----PTSSLTSGLRETSSSERISSAT 8431
Query: 548 SSMTHVSDTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMELQSDPEEQLSENAC 607
T +S+ T + T I + +S+ G + I ++ ++ +LS +
Sbjct: 8432 EGSTVLSEVP--SGATTEVSRTEVISSRGTSMSGP---DQFTISPDISTEAITRLSTSPI 8486
Query: 608 ISETSFSSESPEGACTSLPSPGGETQSTS--------EESCTPASLETTFCSEVSSTENT 659
++E++ S+ + E S G T TS + +P + + +S T
Sbjct: 8487 MTESAESAITIETGSPGATSEGTLTLDTSTTTFWSGTHSTASPGFSHSEMTTLMSRTPGD 8546
Query: 660 DKYNQRNSTDENFHASLMSEISPISTSPEISEASLMSNLP--LTSEASPVSNL----PL- 712
+ S +E S +S +SP ++ S S LP ++S PV+ L P+
Sbjct: 8547 VPWPSLPSVEE------ASSVSSSLSSPAMTSTSFFSTLPESISSSPHPVTALLTLGPVK 8600
Query: 713 TSETSPMSDLPLTSETSSVSS----MLLTSETTFVSSLPLPSETSPISN--SSINERMAH 766
T++ S P TS ++SS +L TSE T PS +P+ N + I + ++
Sbjct: 8601 TTDMLRTSSEPETSSPPNLSSTSAEILATSEVTKDREKIHPSSNTPVVNVGTVIYKHLSP 8660
Query: 767 QQRKSPSVSEEPLSPQKDESSATAKPLGENLTSQQKNLSNTPEPIIMSSSSIAPEAFPSE 826
+ V+ +P SP AT LG S T P + P + +
Sbjct: 8661 SSVLADLVTTKPTSPM-----ATTSTLGNTSVS-------TSTPAFPETMMTQPTSSLTS 8708
Query: 827 DLHNKTLSQQTCKSHVDTEKPYPAS-IPELASTEMIKVKNHSVLQRTEKKVLPSPLELSV 885
L + SQ+T + TE+ S +P A+T++ + + S L RT P P + ++
Sbjct: 8709 GLREISTSQETSSA---TERSASLSGMPTGATTKVSRTEALS-LGRTST---PGPAQSTI 8761
Query: 886 FSEGTDNKGNELPSAKLQDKQYISSVDKAPFSEGSRNKT------HKQGSTQSRLETSHT 939
E + + I+ + + GS T H S+Q +
Sbjct: 8762 SPEIST--------------ETITRISTPLTTTGSAEMTITPKTGHSGASSQGTFTLDTS 8807
Query: 940 SKSSEPSKSPDGIRNESRDSEISKRKTAEQHSFGICKEKRARIEDDQSTRNISS-SSPPE 998
S++S P + + + + S ++S+ +SP
Sbjct: 8808 SRASWPGTHSAATHRSPHSGMTTPMSRGPEDVSWPSRPSVEKTSPPSSLVSLSAVTSPSP 8867
Query: 999 KEQPPREEPRVPPLKIQLSKIGPPFIIKSQPVS----KPESRASTSTSVSGGRNTGARTL 1054
P E PL++ + + P ++K+ + +P + + S +++ + A +
Sbjct: 8868 LYSTPSESSHSSPLRV--TSLFTPVMMKTTDMLDTSLEPVTTSPPSMNITSDESL-ATSK 8924
Query: 1055 ADIKARAQQARAQREAAAAAAVAAAASIVSGAMGSPGEGGKTR---TLAHIKEQTKAKLF 1111
A ++ A Q ++A S G P T T + IK+ +
Sbjct: 8925 ATMETEAIQLSENTAVTQMGTISARQEFYSSYPGLPEPSKVTSPVVTSSTIKDIVSTTIP 8984
Query: 1112 AKHQ-------ARAHLFQTSKETRLPPPLSSKEGPPNLEVSSTPETKMEGSTGVIIVNPN 1164
A + + + L T +ET + S P + + +E S ++ +
Sbjct: 8985 ASSEITRIEMESTSTLTPTPRETSTSQEIHSATKPSTVPYKALTSATIEDSMTQVMSSSR 9044
Query: 1165 CRSPSNKSAHLRETTTVLQQ-SLNPSKLPETATDLSVHSSDENIPVSHLSEKIVSST--S 1221
SP + +T V+ + S +P K T ++ + S+T S
Sbjct: 9045 GPSPDQSTMSQDISTEVITRLSTSPIKTESTEMTITTQTGSPGATSRGTLTLDTSTTFMS 9104
Query: 1222 SENSSVPMLFNKNSVPVSVCSTAISGAIKEHPFVSSVDKSSVLMSVDSANTTISACNISM 1281
+S+ F+ + + + T HP SV+++S SA+ ++S+
Sbjct: 9105 GTHSTASQGFSHSQMTALMSRTPGDVPWLSHP---SVEEAS------SASFSLSS----- 9150
Query: 1282 LKTIQGTDTPCIAIIPKCIESTPISATTEGSSISSSMDDKQLLIS--------------- 1326
P S+P+S+T S SSS+ LL S
Sbjct: 9151 ---------------PVMTSSSPVSSTLPDSIHSSSLPVTSLLTSGLVKTTELLGTSSEP 9195
Query: 1327 -SSSASNLVSTQYTSVPTPSIGNNLPNLSTSSVLIPPMGINNRFPSEKIAIPGSEEQATV 1385
+SS NL ST + + + L ++V+ G + PS +A +AT
Sbjct: 9196 ETSSPPNLSSTSAEILAITEVTTDTEKLEMTNVV--TSGYTHESPSSVLA-DSVTTKATS 9252
Query: 1386 SMGTTVRAALSCSDSVAVTDSLVAHPTVAMFTGNMLTINSYDSPPKLSAESLDKNSGPRN 1445
SMG T D+ +T + T + T + L++ P L S+ + + +
Sbjct: 9253 SMGIT----YPTGDTNVLTSTPAFSDTSRIQTKSKLSLT-----PGLMETSISEETS--S 9301
Query: 1446 RADNSGKPQQPPGGFAPAAINRSIPCKVIVDHSTTLTSSLSLTVSVESSEASLDLQGRPV 1505
+ S P G A ++R+ + I T++ T+S ++S ++ P+
Sbjct: 9302 ATEKSTVLSSVPTG-ATTEVSRT---EAISSSRTSIPGPAQSTMSSDTSMETITRISTPL 9357
Query: 1506 RTEASVQPVACPQVSVISRPEPVANEG---IDHSST 1538
+ S P+ P ++G +D SST
Sbjct: 9358 TRKESTDMAITPKTG----PSGATSQGTFTLDSSST 9389
Score = 59.3 bits (142), Expect = 4e-08
Identities = 230/1120 (20%), Positives = 402/1120 (35%), Gaps = 136/1120 (12%)
Query: 471 KTIPEFSEEAESLTNSHEEPQIAPPEDNLESCVMMNDVLETLPHIEVKIE--GKSESPQE 528
KT + +E +TNS E L + + D +T P + G S S E
Sbjct: 8011 KTTDMLHKSSEPVTNSPANLSSTSVEI-LATSEVTTDTEKTHPSSNRTVTDVGTSSSGHE 8069
Query: 529 EMTVVIDQLEVCDSLIPSTSSMTHVSDTEHKESETAVETSTP------KIKTGSSS---- 578
+ V+ DS +S ++ T +T+V TSTP +I+T +S
Sbjct: 8070 STSFVL-----ADSQTSKVTSPMVITSTME---DTSVSTSTPGFFETSRIQTEPTSSLTL 8121
Query: 579 -LEGQFPNEGIAIDMELQS---------DPEEQLSENACISETSFS-----SESPEGAC- 622
L +EG ++ E+ + E +E S TS S + SPE +
Sbjct: 8122 GLRKTSSSEGTSLATEMSTVLSGVPTGATAEVSRTEVTSSSRTSISGFAQLTVSPETSTE 8181
Query: 623 --TSLPSPGGETQSTS----EESCTPASL-ETTFCSEVSSTENTDKYNQRNSTDENFHAS 675
T LP+ T+S ++ P S E+T ++S+T N ++ + F S
Sbjct: 8182 TITRLPTSSIMTESAEMMIKTQTDPPGSTPESTHTVDISTTPNW--VETHSTVTQRFSHS 8239
Query: 676 LMSEISPISTSPEISEASLMSNLPLTSEASPVSNLPLTSETSPMS----------DLPLT 725
M+ + +S SP S++ TS AS + +LP T+ SP+S LP+T
Sbjct: 8240 EMTTL--VSRSPGDMLWPSQSSVEETSSASSLLSLPATTSPSPVSSTLVEDFPSASLPVT 8297
Query: 726 SETSSVSSMLLTSETTFVSSLPLPSETSPISNSSINERMAHQQRKSPSVSEEPLSPQKDE 785
S + +++T++ +S P S TS +S++S +ER+ + +V E + P
Sbjct: 8298 SLLN--PGLVITTDRMGISREPGTSSTSNLSSTS-HERLTTLE---DTVDTEDMQPSTHT 8351
Query: 786 SSATAKPLGENLTSQQKNLSNTPEPIIMSSSSIAPEAFPSEDLHNKTLSQQTCKSHVDTE 845
+ + SQ LS++ P S + + + +T + ++
Sbjct: 8352 AVTNVRTSISGHESQSSVLSDSETPKATSPMGTTYTMGETSVSISTSDFFETSRIQIEPT 8411
Query: 846 KPYPASIPELASTEMIK--VKNHSVLQRTEKKVLPSPLELSVF-SEGTDNKGNELPSAKL 902
+ + E +S+E I + +VL V S GT G +
Sbjct: 8412 SSLTSGLRETSSSERISSATEGSTVLSEVPSGATTEVSRTEVISSRGTSMSGPD------ 8465
Query: 903 QDKQYISSVDKAPFSEGSRNKTHKQGSTQSRLETSHTSKSSEPSKSPDGIRNESRDSEIS 962
Q+ S D + +E + T+S E++ T ++ P + +G +
Sbjct: 8466 ---QFTISPDIS--TEAITRLSTSPIMTES-AESAITIETGSPGATSEGTLTLDTSTTTF 8519
Query: 963 KRKTAEQHSFGICKEKRARIEDDQSTRNISSSSPPEKEQPPREEPRVPPLKIQLSKIGPP 1022
T S G + + S +P + P P V S + P
Sbjct: 8520 WSGTHSTASPGFSHSEMT---------TLMSRTPGDVPWP--SLPSVEEASSVSSSLSSP 8568
Query: 1023 FIIKSQPVSK-PESRASTSTSVSGGRNTGARTLADIKARAQQARAQREAAAAAAVAAAAS 1081
+ + S PES +S+ V T TL +K R E ++ S
Sbjct: 8569 AMTSTSFFSTLPESISSSPHPV-----TALLTLGPVKT-TDMLRTSSEPETSS--PPNLS 8620
Query: 1082 IVSGAMGSPGEGGKTRTLAHIKEQTK----AKLFAKHQARAHLFQTSKETRLPPPLSSKE 1137
S + + E K R H T + KH + + + T+ P+++
Sbjct: 8621 STSAEILATSEVTKDREKIHPSSNTPVVNVGTVIYKHLSPSSVLADLVTTKPTSPMATTS 8680
Query: 1138 GPPNLEVSST----PETKMEGSTGVIIVNPNCRSPSNKSAHLRETTTVLQQSLNPSKLPE 1193
N VS++ PET M T + S + + +ET++ ++S + S +P
Sbjct: 8681 TLGNTSVSTSTPAFPETMMTQPTS------SLTSGLREISTSQETSSATERSASLSGMPT 8734
Query: 1194 TATD-------LSVHSSDENIPVSHLSEKIVSSTSSENSSVPMLFNKNSVPVSVCSTAIS 1246
AT LS+ + P +S+ + S P+ ++ T S
Sbjct: 8735 GATTKVSRTEALSLGRTSTPGPAQSTISPEISTETITRISTPLTTTGSAEMTITPKTGHS 8794
Query: 1247 GAIKEHPFVSSVDKSSVLMSVDSANTTISACNISMLKTIQGTDTPCIAIIPKCIESTPIS 1306
GA + F + SA T S + +G + P +++P S
Sbjct: 8795 GASSQGTFTLDTSSRASWPGTHSAATHRSPHSGMTTPMSRGPEDVSWPSRPSVEKTSPPS 8854
Query: 1307 ATTEGSSISSSMDDKQLLISSSSASNLVSTQYTSVPTPSIGNNLPNLSTS--SVLIPPMG 1364
+ S+++S L + S +S+ + TS+ TP + L TS V P
Sbjct: 8855 SLVSLSAVTS---PSPLYSTPSESSHSSPLRVTSLFTPVMMKTTDMLDTSLEPVTTSPPS 8911
Query: 1365 IN---------NRFPSEKIAIPGSEEQATVSMGT-TVRAALSCSDSVAVTDSLVAHPTVA 1414
+N ++ E AI SE A MGT + R S S V P V
Sbjct: 8912 MNITSDESLATSKATMETEAIQLSENTAVTQMGTISARQEFYSSYPGLPEPSKVTSPVVT 8971
Query: 1415 MFTGNMLTINSYDSPPKLSAESLDKNSGPRNRADNSGKPQQPPGGFAPAAINRSIPCKVI 1474
T + + + +++ ++ S + Q+ P+ +
Sbjct: 8972 SSTIKDIVSTTIPASSEITRIEMESTSTLTPTPRETSTSQEIHSATKPSTVPYKALTSAT 9031
Query: 1475 VDHSTTLTSSLSLTVSVESSEASLDLQGRPVRTEASVQPV 1514
++ S T S S S + S S D+ V T S P+
Sbjct: 9032 IEDSMTQVMSSSRGPSPDQSTMSQDI-STEVITRLSTSPI 9070
Score = 58.5 bits (140), Expect = 7e-08
Identities = 207/1008 (20%), Positives = 355/1008 (35%), Gaps = 180/1008 (17%)
Query: 676 LMSEISPISTSPEISEASLMSNLPLTSEAS--PVSNLPLTSETSPMSDLPLTSETSS--- 730
+MS P STS ++ + ++ L+ + + P N P TS S +S P T +S+
Sbjct: 81 VMSSALPESTSRGMTHSEQRTSPSLSPQVNGTPSRNYPATSMVSGLSS-PRTRTSSTEGN 139
Query: 731 ----VSSMLLTSETT---FVSSLPLPSETSPISNSSI----NERMAHQQRKSPSVSEEPL 779
S+ LT ETT +P+ETS S + R + SP +
Sbjct: 140 FTKEASTYTLTVETTSGPVTEKYTVPTETSTTEGDSTETPWDTRYIPVKITSPMKTFADS 199
Query: 780 SPQKDESSATAKPLGENLTSQQKNLSNTPEPIIMSSS--SIAPEAFPSEDLHNKTLSQQT 837
+ K+ + + P +T P + SS ++P+ P+ +T
Sbjct: 200 TASKENAPVSMTPAETTVTDSHTPGRTNPSFGTLYSSFLDLSPKGTPNS-------RGET 252
Query: 838 CKSHVDTEKPYPASIPELASTEMIKVKNHSVLQRTEKKVLPSPLELSVFSEGT------- 890
+ + YP S PE S ++ + L + + E S+FS +
Sbjct: 253 SLELILSTTGYPFSSPEPGSAGHSRISTSAPLSSSASVLDNKISETSIFSGQSLTSPLSP 312
Query: 891 ---DNKGNELPSAKLQDKQYISSVDKAPFSEGSRNKTHKQG----STQSRLET------- 936
+ + + +P++ + +S+ + + +E R+ G ST+ ET
Sbjct: 313 GVPEARASTMPNSAIPFSMTLSNAETS--AERVRSTISSLGTPSISTKQTAETILTFHAF 370
Query: 937 --------SHTSKS--SEPSKSPDGIRNESRDSEISKRKTAEQHSFGICKEKRARIEDDQ 986
+H +K+ SE SP + S + + + S ++ +
Sbjct: 371 AETMDIPSTHIAKTLASEWLGSPGTLGGTSTSALTTTSPSTTLVSEETNTHHSTSGKETE 430
Query: 987 STRNISSSSPPEKEQPPREEPRVPPLKIQL------SKIGPPFIIKSQPVSKPESRASTS 1040
T N +S +P E P E L L SKI P + S ++ E R + S
Sbjct: 431 GTLN-TSMTPLETSAPGEESEMTATLVPTLGFTTLDSKIRSPSQVSSSHPTR-ELRTTGS 488
Query: 1041 TSVSGGRNTGARTLADIKARAQQARAQREAAAAAAVAAAASIVSGAMGSPGEGGKTRTLA 1100
TS +T A +DI A ++ + A+S S
Sbjct: 489 TSGRQSSSTAAHGSSDILR-----------ATTSSTSKASSWTS---------------- 521
Query: 1101 HIKEQTKAKLFAKHQARAHLFQT-SKETRLPPPLSSKEGPPNLEVSSTPETKMEGSTGVI 1159
++ A+ F++ Q + + S +T PP +S P V S + G T +
Sbjct: 522 ----ESTAQQFSEPQHTQWVETSPSMKTERPPASTSVAAPITTSVPSV----VSGFTTL- 572
Query: 1160 IVNPNCRSPSNKSAHLRETT--TVLQQSLNPSKLPETA--TDLSVHSSDENIPVSHLSEK 1215
++ S K L ET+ T++ +S + A T +S+ +
Sbjct: 573 ------KTSSTKGIWLEETSADTLIGESTAGPTTHQFAVPTGISMTGGSSTRGSQGTTHL 626
Query: 1216 IVSSTSSENSSVPMLFNKNSVPVSVCSTAISGAIKEHP----FVSSVDKSSVLMSVDSAN 1271
+ +T+S +S + N VPVSV A P S SSV+ S
Sbjct: 627 LTRATASSETSADLTLATNGVPVSVSPAVSKTAAGSSPPGGTKPSYTMVSSVIPETSSLQ 686
Query: 1272 TTISACNISMLKTIQGTDTPCIAIIPKCIESTPISATTEGSSISSSMDDKQLLISSSSAS 1331
++ S+ T T P + P T IS + S +S ++DK + ++S+ S
Sbjct: 687 SSAFREGTSLGLTPLNTRHPFSSPEPDSAGHTKISTSIPLLSSASVLEDK--VSATSTFS 744
Query: 1332 NLVSTQYTSVPTPSIGNN-------LPNLSTSSVLIPPMGINNRFPSEKIAIPGSEEQAT 1384
+ +T + TP I L +++ S+ P + N P EE
Sbjct: 745 HHKATSSITTGTPEISTKTKPSSAVLSSMTLSNAATSPERVRNATSPLTHPSPSGEE--- 801
Query: 1385 VSMGTTVRAALSCSDSVAVTDSLVAHPTVAMFTGNMLTINSYDSPPKLSAESLD------ 1438
T + L+ S S TDS HPT LT S +SP LS S+
Sbjct: 802 -----TAGSVLTLSTSAETTDSPNIHPT------GTLTSESSESPSTLSLPSVSGVKTTF 850
Query: 1439 KNSGPRNRADNSG------------KPQQPPGGFAPAAINRSIPCKVIVDHST------- 1479
+S P SG +P+ + S+P V T
Sbjct: 851 SSSTPSTHLFTSGEETEETSNPSVSQPETSVSRVRTTLASTSVPTPVFPTMDTWPTRSAQ 910
Query: 1480 ----------TLTSSLSLTVSVESSEASLD-LQGRPVRTEA---SVQPVACPQVSVISRP 1525
TSS S+T S S+ + L G ++ + A PQ +
Sbjct: 911 FSSSHLVSELRATSSTSVTNSTGSALPKISHLTGTATMSQTNRDTFNDSAAPQSTTWPET 970
Query: 1526 EPVANEGIDHSSTFIAASAAKQDSKTLPATCTSLRELPLVPDKLNEPT 1573
P G+ ++T ++ SA + + + TS + + EP+
Sbjct: 971 SPRFKTGLPSATTTVSTSATSLSATVMVSKFTSPATSSMEATSIREPS 1018
Score = 57.0 bits (136), Expect = 2e-07
Identities = 204/998 (20%), Positives = 362/998 (36%), Gaps = 116/998 (11%)
Query: 595 QSDPEEQLSENACISETSFSSESPEGACTSLPSPGGETQSTSEESCTPASLETTFCSEVS 654
QS EE S ++ +S + +S SP + P TS P + TT +S
Sbjct: 8257 QSSVEETSSASSLLSLPATTSPSPVSSTLVEDFPSASLPVTS--LLNPGLVITTDRMGIS 8314
Query: 655 STENTDKYNQRNSTDENFHASLMSEISPISTSPEISEASLMSNLPLT---SEASPVSNLP 711
T + +ST +L + P A ++ S++S +S+
Sbjct: 8315 REPGTSSTSNLSSTSHERLTTLEDTVDTEDMQPSTHTAVTNVRTSISGHESQSSVLSDSE 8374
Query: 712 LTSETSPMSDLPLTSETSSVSSMLLTSETTFVSSLPLPSETSPISNSSINERMAHQQRKS 771
TSPM ETS S ET+ + P S TS + +S +ER++ S
Sbjct: 8375 TPKATSPMGTTYTMGETSVSISTSDFFETSRIQIEPTSSLTSGLRETSSSERISSATEGS 8434
Query: 772 PSVSEEPLSPQKDESSATAKPLGENLTSQQKNLSNTPEPIIMSSSSIAPEAFPSEDLHNK 831
+SE P S AT + + S + + P+ + S I+ EA L
Sbjct: 8435 TVLSEVP-------SGATTEVSRTEVISSRGTSMSGPDQFTI-SPDISTEAITR--LSTS 8484
Query: 832 TLSQQTCKSHVDTEKPYPASIPELASTEMIKVKNHSVLQRTEKKVLP--SPLELSVFSEG 889
+ ++ +S + E P + E T + + T P S E++
Sbjct: 8485 PIMTESAESAITIETGSPGATSE--GTLTLDTSTTTFWSGTHSTASPGFSHSEMTTLMSR 8542
Query: 890 TDNKGNELPSAKLQDKQYISSVDKAPFSEGSRNKTHKQGSTQSRLETSH---TSKSSEPS 946
T ++P L + SSV + S + + +S + H + P
Sbjct: 8543 TP---GDVPWPSLPSVEEASSVSSSLSSPAMTSTSFFSTLPESISSSPHPVTALLTLGPV 8599
Query: 947 KSPDGIRNESRDSEISKRKTAEQHSFGICKEKRARIEDDQSTRNISSSSPPEKEQPPREE 1006
K+ D +R S + E S S I +T ++ EK P
Sbjct: 8600 KTTDMLRTSS-EPETSSPPNLSSTSAEIL-----------ATSEVTKDR--EKIHPSSNT 8645
Query: 1007 PRVPPLKIQLSKIGPPFIIKSQPVSKPESRASTSTSVSGGRNTGARTLADIKARAQQARA 1066
P V + + P ++ +KP S +T TS G + T A + Q +
Sbjct: 8646 PVVNVGTVIYKHLSPSSVLADLVTTKPTSPMAT-TSTLGNTSVSTSTPAFPETMMTQPTS 8704
Query: 1067 Q-----REAAAAAAVAAAASIVSGAMGSPGEGGKTRTLAHIKEQTKAKLFAKHQARAHL- 1120
RE + + ++A + G P G T ++ + + + A++ +
Sbjct: 8705 SLTSGLREISTSQETSSATERSASLSGMP--TGATTKVSRTEALSLGRTSTPGPAQSTIS 8762
Query: 1121 --FQTSKETRLPPPLSSKEGPPNLEVSSTPETKMEG--STGVIIVNPNCR--------SP 1168
T TR+ PL++ + E++ TP+T G S G ++ + R +
Sbjct: 8763 PEISTETITRISTPLTT---TGSAEMTITPKTGHSGASSQGTFTLDTSSRASWPGTHSAA 8819
Query: 1169 SNKSAHLRETTTVLQQSLNPSKLPETATDLSVHSSDENIPVSHL-------SEKIVSSTS 1221
+++S H TT + S+ PE + S S ++ P S L S + ST
Sbjct: 8820 THRSPHSGMTTPM-------SRGPEDVSWPSRPSVEKTSPPSSLVSLSAVTSPSPLYSTP 8872
Query: 1222 SENS-SVPMLFNKNSVPVSVCSTAISGAIKEHPFVSSVDKSSVLM--SVDSANTTISACN 1278
SE+S S P+ PV + +T + E P +S ++ S+ ++ T+
Sbjct: 8873 SESSHSSPLRVTSLFTPVMMKTTDMLDTSLE-PVTTSPPSMNITSDESLATSKATMETEA 8931
Query: 1279 ISMLKTIQGTDTPCIAIIPKCIESTPISATTEGSSISSSMDDKQLLISSSSASNLVSTQY 1338
I + + T I+ + S P E S ++S +++SS+ ++VS
Sbjct: 8932 IQLSENTAVTQMGTISARQEFYSSYP--GLPEPSKVTSP------VVTSSTIKDIVS--- 8980
Query: 1339 TSVPTPSIGNNLPNLSTSSVLIPPMGINNRFPSEKIAIPGSEEQATVSMGTTVRAALSCS 1398
T++P S + STS++ P R S I + + +TV A + S
Sbjct: 8981 TTIPASSEITRIEMESTSTLTPTP-----RETSTSQEIHSATKPSTVPYKALTSATIEDS 9035
Query: 1399 DSVAVTDSLVAHPTVAMFTGNMLTINSYDSPPKLSAESLDKNSGPRNRADNSGKPQQPPG 1458
+ ++ S P + + ++ T + +LS + S +G P
Sbjct: 9036 MTQVMSSSRGPSPDQSTMSQDIST----EVITRLSTSPIKTESTEMTITTQTGSPGATSR 9091
Query: 1459 GFAPAAINRSIPCKVIVDHSTTLTSSLSLTVSVESSEASLDLQGRPVRTEASVQPVACPQ 1518
G + +D STT S T S S + + RT V ++ P
Sbjct: 9092 G------------TLTLDTSTTFMSGTHSTASQGFSHS--QMTALMSRTPGDVPWLSHPS 9137
Query: 1519 VSVISRPEPVANEGIDHSSTFIAASAAKQ-DSKTLPAT 1555
V S + + SS+ ++++ S +LP T
Sbjct: 9138 VEEASSASFSLSSPVMTSSSPVSSTLPDSIHSSSLPVT 9175
Score = 56.2 bits (134), Expect = 3e-07
Identities = 231/1159 (19%), Positives = 417/1159 (35%), Gaps = 170/1159 (14%)
Query: 526 PQEEMTVVIDQLEVCDSLIPSTSSMTHVSDTEHKESETAVETSTPKIKTGSSSLEGQFPN 585
P + ++ V+ + D+++ +T M S E E+ + + TP ++ +S +
Sbjct: 9542 PTKVISPVVTSSSIRDNMVSTT--MPGSSGITRIEIES-MSSLTPGLRETRTSQDITSST 9598
Query: 586 EGIAIDMELQSDPEEQLSENACISETSFSSESPEGACTSLPSPGGETQSTSEESCTPASL 645
E + ++ S ++S + + S P + SL S S
Sbjct: 9599 ETSTVLYKMPSGATPEVSRTEVMPSSRTSIPGPAQSTMSLDISDEVVTRLSTSPIMTESA 9658
Query: 646 ETTFCSEVSSTENTDKYNQRNSTDENFHASLMSEISPISTSPEISEASLMSNLPLTSEAS 705
E T ++ + T + T F + S +S + E++ +LMS P + +
Sbjct: 9659 EITITTQTGYSLATSQVTLPLGTSMTFLSGTHSTMSQGLSHSEMT--NLMSRGPESLSWT 9716
Query: 706 PVSNLPLTSETSPMSDLPLTSETSSVSSMLLTSETTFVSSLPLPSETSPISNSSINERMA 765
+ T +S ++ LPLT+ S VSS LL S S PLP TS I +
Sbjct: 9717 SPRFVETTRSSSSLTSLPLTTSLSPVSSTLLDSS----PSSPLP-VTSLILPGLVKTTEV 9771
Query: 766 HQQRKSPSVSEEP-LSPQKDESSATAKPLGENLTSQQKNLSNTPEPIIMSSSSIAPEAFP 824
P S P LS E AT++ + + T + SNT + +SSS+
Sbjct: 9772 LDTSSEPKTSSSPNLSSTSVEIPATSEIMTD--TEKIHPSSNTAVAKVRTSSSV------ 9823
Query: 825 SEDLHNKTLSQQTCKSHVDTEKPYPASIPELASTEMIKVKN--HSVLQRTEKKVLPSPLE 882
+ H+ L+ D+E +IP + T + S +E + +P+
Sbjct: 9824 -HESHSSVLA--------DSET--TITIPSMGITSAVDDTTVFTSNPAFSETRRIPTEPT 9872
Query: 883 LSVFSEGTDNKGNELPSAKLQDKQYISSVDKAPFSEGSRNKTHKQGSTQSRLETSHTSKS 942
S+ + +E ++ + + V + +E S + + +R+ H S
Sbjct: 9873 FSLTPGFRETSTSEETTSITETSAVLYGVPTSATTEVSMTEI----MSSNRI---HIPDS 9925
Query: 943 SEPSKSPDGIRNESRDSEISKRKTAEQHSFGICKEKRARIEDDQSTRNISSSSPP----E 998
+ + SPD I E S +E I +K + QST +++++ P
Sbjct: 9926 DQSTMSPD-IITEVITRLSSSSMMSESTQMTITTQKSSPGATAQSTLTLATTTAPLARTH 9984
Query: 999 KEQPPR-----------EEPRVPPLKIQL--SKIGPPFIIKSQPVSK--------PESRA 1037
PPR P P K L K + S PV+ P+S
Sbjct: 9985 STVPPRFLHSEMTTLMSRSPENPSWKSSLFVEKTSSSSSLLSLPVTTSPSVSSTLPQSIP 10044
Query: 1038 STSTSVSGGRNTGARTLADIKARAQQARAQREAAAAAAVAAAASIVSGAMGSPGEGGKTR 1097
S+S SV+ G D + + + + + AA+ + + + K
Sbjct: 10045 SSSFSVTSLLTPGMVKTTDTSTEPGTSLSPNLSGTSVEILAASEVTT-------DTEKIH 10097
Query: 1098 TLAHIKEQTKAKLFAKHQARAHLFQTSKETRLPPPLSSKEGPPNLEVSSTPETKMEGSTG 1157
+ + + H+ + + S+ ++ P+ + +S++ E +TG
Sbjct: 10098 PSSSMAVTNVGTTSSGHELYSSVSIHSEPSKATYPVGTPSSMAETSISTSMPANFE-TTG 10156
Query: 1158 VIIVNPNCRSPSNKSAHLRETTTVLQQSLNPSKLPETATDLSVHSSDENIPVSHLSEK-- 1215
+ +HL SL+ S + T T S S +HL +
Sbjct: 10157 F---------EAEPFSHLTSGFRKTNMSLDTSSVTPTNTPSSPGS-------THLLQSSK 10200
Query: 1216 --IVSSTSSENSSVPMLFNKNSVPVSVCST-AISGAIKEHPFVSSVDKSSVLMSVDSANT 1272
SS + + P +PV + + S +I E ++S +S MSV +
Sbjct: 10201 TDFTSSAKTSSPDWPPASQYTEIPVDIITPFNASPSITESTGITSFPESRFTMSVTESTH 10260
Query: 1273 TISACNISMLKTIQ-GTDTPCIAI---------IPKCI--ESTPISATTEGSSISSSMDD 1320
+S + +TI GT P ++ +P+ I +P S T G ++
Sbjct: 10261 HLSTDLLPSAETISTGTVMPSLSEAMTSFATTGVPRAISGSGSPFSRTESGPGDATLSTI 10320
Query: 1321 KQLLISSS----SASNLVSTQYTSVP----------TP-----SIGNNLPNLSTSSVLIP 1361
+ L SS+ S+S +T +++P TP S+G V++
Sbjct: 10321 AESLPSSTPVPFSSSTFTTTDSSTIPALHEITSSSATPYRVDTSLGTESSTTEGRLVMVS 10380
Query: 1362 PMGINNRFPSEKIAIPGSEEQAT--VSMGTTVRA--ALSCSDSVAVTDSLVAHPTVAMFT 1417
+ +++ P + P + + T V +GT A S S + TD ++ H T
Sbjct: 10381 TLDTSSQ-PGRTSSSPILDTRMTESVELGTVTSAYQVPSLSTRLTRTDGIMEHIT----- 10434
Query: 1418 GNMLTINSYDSPPKLSAESLDKNS-GPRNRADNSGKPQQPPGGFAPAAINRSIPCKVIVD 1476
K+ E+ + + P S P P G +
Sbjct: 10435 -------------KIPNEAAHRGTIRPVKGPQTSTSPASPKGLHTGGTKRMETTTTALKT 10481
Query: 1477 HSTTL--TSSLSLTVSVESSEASLDLQGRPVRTEASVQPVA-CPQVSVISRPEPVANEGI 1533
+T L TS +LT SV + G AS+Q + P +I+ P + +
Sbjct: 10482 TTTALKTTSRATLTTSVYTPTL-----GTLTPLNASMQMASTIPTEMMITTPYVFPD--V 10534
Query: 1534 DHSSTFIAASAAKQDSKTLPATCTSLRELPLVPDKLNEPTAPSHNFAEQARGPA-----P 1588
+++ +A S + S LP R P V ++ +E TA + + R P
Sbjct: 10535 PETTSSLATSLGAETSTALP------RTTPSVFNRESETTASLVSRSGAERSPVIQTLDV 10588
Query: 1589 FKSEADTTCSNQYNPSNRI 1607
SE DTT S +P+ I
Sbjct: 10589 SSSEPDTTASWVIHPAETI 10607
Score = 52.4 bits (124), Expect = 5e-06
Identities = 226/1141 (19%), Positives = 403/1141 (35%), Gaps = 163/1141 (14%)
Query: 542 SLIPSTSSMTHVSDTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMELQSDPEEQ 601
S +P ++T SD SE+ T+ P + T SS+ G + + E
Sbjct: 2142 SEVPLPMAITSRSDVSGLTSES---TANPSLGTASSA--------GTKLTRTISLPTSES 2190
Query: 602 LSENACISETSFSSESPEGACTSLPSPGGETQSTSEESCTPASLETTFCSEVSSTENTDK 661
L +++ ++ P G S P+ ET S S P L T S +T
Sbjct: 2191 LVSFR-MNKDPWTVSIPLG---SHPTTNTET-SIPVNSAGPPGLSTV----ASDVIDTPS 2241
Query: 662 YNQRNSTDENFHASLMSEISPISTSPEISEASLMSNLPLTSE-ASPVSNLPLTSETSPMS 720
+ +F S +E++ IS PE + S + LT E S V+ +P +S MS
Sbjct: 2242 DGAESIPTVSFSPSPDTEVTTISHFPEKTTHSFRTISSLTHELTSRVTPIPGDWMSSAMS 2301
Query: 721 DLP--------------LTSETSSVSSMLLTSETTFVSSLPLPSETSPISNSSINERMAH 766
P +TS + S ++LT+ T S++ L +ET+ ++ ++ R +
Sbjct: 2302 TKPTGASPSITLGERRTITSAAPTTSPIVLTASFTETSTVSLDNETTVKTSDILDARKTN 2361
Query: 767 QQRKSPSVSEEPLSPQKDESSATAKPLGENLTSQQKNLSNTPEPIIMSSSSIAPEAFPSE 826
+ S S + ++ + + K S +P I ++S +P F S+
Sbjct: 2362 ELPSDSSSSSDLINTS----------IASSTMDVTKTASISPTSISGMTASSSPSLFSSD 2411
Query: 827 --DLHNKTLSQQTCKSHVDTEKPY-----------PASIPELASTEMIKVKNHSVLQRTE 873
+ T T S + Y P+++P T ++ + +
Sbjct: 2412 RPQVPTSTTETNTATSPSVSSNTYSLDGGSNVGGTPSTLPPFTITHPVETSSALLAWSRP 2471
Query: 874 KKVLPSPLELSVFSEGTDNKGNELPSAKLQDKQYISSVDKAPFSEGSRNKTHKQGSTQSR 933
+ + + S N + ++ + S KT G S
Sbjct: 2472 VRTFSTMVSTDTASGENPTSSNSVVTSVPAPGTWTSVGSTTDLPAMGFLKTSPAGEAHSL 2531
Query: 934 L-ETSHTSKSSEPSKSPDGIRNESRDSEISKRKTAEQHSFGICKEKRARIEDDQSTRNIS 992
L T + + P S + S SE S T+E + + S N
Sbjct: 2532 LASTIEPATAFTPHLSAAVVTGSSATSEASLLTTSESKAIHSSPQTPT---TPTSGANWE 2588
Query: 993 SSSPPEKEQPPREEPRVPPLKIQLSKIGPPFIIKSQPVSKPESRASTSTSVSGGRNTGAR 1052
+S+ PE E SKI I VS P S+ ++ ++SG +
Sbjct: 2589 TSATPESLLVVTETSDT----TLTSKILVTDTILFSTVSTPPSKFPSTGTLSGA--SFPT 2642
Query: 1053 TLADIKARAQQARAQREAAAAAAVAA-AASIVSGAMGSPGE---------GGKTRTLAHI 1102
L D A A + A + + +I S ++G+ E G L +
Sbjct: 2643 LLPDTPAIPLTATEPTSSLATSFDSTPLVTIASDSLGTVPETTLTMSETSNGDALVLKTV 2702
Query: 1103 KEQTKA----KLFAKHQARAHLFQTSKETRLPPPLSSKEGPPNLEVSSTPETKMEGSTGV 1158
++ + ++ H TS + P ++ EG + +S+ P G+TG
Sbjct: 2703 SNPDRSIPGITIQGVTESPLHPSSTSPSKIVAPRNTTYEGSITVALSTLP----AGTTGS 2758
Query: 1159 IIVNPNCR----------SPSNKSAHLRETTTVLQQSLNPSKLPETATDLSVHSSDENIP 1208
++ + + S + A + TT Q + + +T + + ++P
Sbjct: 2759 LVFSQSSENSETTALVDSSAGLERASVMPLTTGSQGMASSGGIRSGSTHSTGTKTFSSLP 2818
Query: 1209 -------VSHLSEKIVSSTSSENSSVPMLFNKNSVPVSVCSTAISGAIKEHPFVSSVDKS 1261
V+ +SE + ++ S+ P +PV S A SG + P +S S
Sbjct: 2819 LTMNPGEVTAMSEITTNRLTATQSTAP-----KGIPVKPTS-AESGLLT--PVSASSSPS 2870
Query: 1262 SVLMSVDSANTTISACNISMLKTIQGTDTPCI----AIIP---KCIESTPIS-ATTEGSS 1313
S+ +A T ++ T + ++ P + A +P + + + P S A+T SS
Sbjct: 2871 KAFASLTTAPPTWGIPQSTL--TFEFSEVPSLDTKSASLPTPGQSLNTIPDSDASTASSS 2928
Query: 1314 ISSSMDDK---QLLISSS--SASNLVSTQYTSVP----TPSIGNNLPNLSTSSVLIPPMG 1364
+S S + +++ S+ SAS+ ST +T P +PS+ + P + TS P
Sbjct: 2929 LSKSPEKNPRARMMTSTKAISASSFQSTGFTETPEGSASPSMAGHEPRVPTSGTGDP--- 2985
Query: 1365 INNRFPSEKIAIPGSEEQATVSMGTTVRAALSCSDSVAVTDSLVAHPTVAMFTGNMLTIN 1424
R+ SE ++ P S + S + SL + T TG
Sbjct: 2986 ---RYASESMSYPDP----------------SKASSAMTSTSLASKLTTLFSTGQAARSG 3026
Query: 1425 SYDSPPKLSAESLDKNSGPRNRADNSGKPQ---QPPGGFAPAAINRSIPCKVIVDHSTTL 1481
S SP LS E P A S K P P + + + ++TL
Sbjct: 3027 SSSSPISLSTEKETSFLSP--TASTSRKTSLFLGPSMARQPNILVHLQTSALTLSPTSTL 3084
Query: 1482 TSSLSLTVSVESSEASLDLQGRPVRTEA-----SVQPVACPQVSVISRPEPVANEGIDHS 1536
S + SS+ + +G T+ S P + VS + P +
Sbjct: 3085 NMSQEEPPELTSSQTIAEEEGTTAETQTLTFTPSETPTSLLPVSSPTEPTARRKSSPETW 3144
Query: 1537 STFIAASAAKQDSKTLPATCTSLRELPLVPDKLNEP-TAPSHNFAEQARGPAPFKSEADT 1595
++ I+ A +T T + ++ + N AP+ G +P E T
Sbjct: 3145 ASSISVPAKTSLVETTDGTLVTTIKMSSQAAQGNSTWPAPAEETGSSPAGTSPGSPEMST 3204
Query: 1596 T 1596
T
Sbjct: 3205 T 3205
Score = 51.2 bits (121), Expect = 1e-05
Identities = 266/1364 (19%), Positives = 493/1364 (36%), Gaps = 218/1364 (15%)
Query: 534 IDQLEVCDSLIP--STSSMTHVSDTE--HKESETAVETSTPKIKTG----SSSLEGQFPN 585
+++ SL+P +T+S +++ T H S T TS +T ++ +
Sbjct: 4153 VEETSSSSSLVPIHATTSPSNILLTSQGHSPSSTPPVTSVFLSETSGLGKTTDMSRISLE 4212
Query: 586 EGIAIDMELQSDPEEQLSENACISETSFSSESPEGACTSLPSPGGETQSTSEESCTPASL 645
G ++ L S E LS +T S + A T++ + E + +
Sbjct: 4213 PGTSLPPNLSSTAGEALSTYEASRDTKAIHHSADTAVTNMEATSSEYSPIPGHTKPSKAT 4272
Query: 646 ETTFCSEVSS--TENTDKYNQRNSTDENFHASLMSEISPISTSPEISEASLMSNLPLTSE 703
S + T +T + +T+ +S+ + STS S A+ S + +T
Sbjct: 4273 SPLVTSHIMGDITSSTSVFGSSETTEIETVSSVNQGLQERSTSQVASSATETSTV-ITHV 4331
Query: 704 ASPVSNLPLT-------SETSPMSDLPLTSETSSVSSMLLTSETTFV----SSLPLPSET 752
+S + +T S TS S + T++ + + T+ + S + + ++T
Sbjct: 4332 SSGDATTHVTKTQATFSSGTSISSPHQFITSTNTFTDVSTNPSTSLIMTESSGVTITTQT 4391
Query: 753 SPISNSSINERMAHQQRKSPSVSEEPLSPQKDESSATAKPLGENLTSQQKNLSNTPEPII 812
P ++ + P ++E PL+ D + L ++ K++S T P +
Sbjct: 4392 GPTGAATQGPYLLDTSTM-PYLTETPLAVTPDFMQSEKTTL---ISKGPKDVSWTSPPSV 4447
Query: 813 MSSS---SIAPEAFPSEDLHNKTLSQQTCKSHVDTEKPYPASIPELASTEMIKVKNHSVL 869
+S S+ P + TL Q S P S + ++ ++K + +L
Sbjct: 4448 AETSYPSSLTPFLVTTIPPATSTLQGQHTSS--------PVSATSVLTSGLVKTTD--ML 4497
Query: 870 QRTEKKVLPSPLELSVFSEGTDNKGNELPS--AKLQDKQYIS-SVDKAPFSEGSRNKTHK 926
+ + V SP L+ N NE+ + A D + I S++KA + G+ + H
Sbjct: 4498 NTSMEPVTNSPQNLN-------NPSNEILATLAATTDIETIHPSINKAVTNMGTASSAHV 4550
Query: 927 QGSTQSRLETSHTSKSSEP------------SKSPDGIRNESRDSEISKRKTAEQHSFGI 974
ST +S S ++ P S S G + E + TA +
Sbjct: 4551 LHSTLP--VSSEPSTATSPMVPASSMGDALASISIPGSETTDIEGEPTSSLTAGRKENST 4608
Query: 975 CKEKRARIEDDQSTRNISSSSPPE--KEQPPREEPRVPPLKIQLSKIGPPFIIKSQPVSK 1032
+E + E + N+S + E K + P + P Q +K F + S +S
Sbjct: 4609 LQEMNSTTESNIILSNVSVGAITEATKMEVPSFDATFIPTPAQSTKFPDIFSVASSRLSN 4668
Query: 1033 -PESRASTSTSVSGGRNTGARTLADIKARAQQARAQREAAAAAAVAAAASIVSGAMGSPG 1091
P ST + + ++GA + +A S + + G+P
Sbjct: 4669 SPPMTISTHMTTTQTGSSGA-------------------TSKIPLALDTSTLETSAGTPS 4709
Query: 1092 EGGKTRTLAHIKEQTKAKLFAKHQARAHLFQTSKETRLPPPLSSKEGPPNLEVSSTPETK 1151
T AH K T K ++ + PP + P+ + + T
Sbjct: 4710 V--VTEGFAHSKITTAMNNDVKDVSQTN-----------PPFQDEASSPSSQ-APVLVTT 4755
Query: 1152 MEGSTGVIIVNPNCRSPSNKSAHLRETTTVLQQSLNPSKLPETATDLSVHSSDENIPVSH 1211
+ S + SP + S+ L + ++ S T++ S+ ++ ++I V+
Sbjct: 4756 LPSSVAFTPQWHSTSSPVSMSSVLTSSLVKTAGKVDTSLETVTSSPQSMSNTLDDISVTS 4815
Query: 1212 LSEKIVSSTSSENSSVPMLFNKNSVPVSVCSTAISGAIKEHPFVSSVDKSSVLMSVDSAN 1271
++T+ ++ P + N+V +V +T A + H VS+ + S + S +
Sbjct: 4816 ------AATTDIETTHPSI---NTVVTNVGTTG--SAFESHSTVSAYPEPSKVTSPNVTT 4864
Query: 1272 TTISACNISML-----KTIQGTDTPCIAIIPKCIESTPISATTEGSSISSSMDDKQLLIS 1326
+T+ IS KT + ++ PK + T IS S+ +S++ K+L +
Sbjct: 4865 STMEDTTISRSIPKSSKTTRTETETTSSLTPK-LRETSISQEITSSTETSTVPYKELTGA 4923
Query: 1327 SS--SASNLVSTQYTSVPTPSIGNNLPNLSTSSVLIPPMGINNRFPSEKIAIPGSEEQAT 1384
++ S +++ S+ TS P P ++ST + N R + I +E T
Sbjct: 4924 TTEVSRTDVTSSSSTSFPGPDQSTVSLDISTET--------NTRLSTSPIMTESAEITIT 4975
Query: 1385 VSMG-------TTVRAALSCSDSVAVTDSLVAHP----TVAMFTGNMLTINSYDSPPKLS 1433
G T S + A S + H V + S+ SPP
Sbjct: 4976 TQTGPHGATSQDTFTMDPSNTTPQAGIHSAMTHGFSQLDVTTLMSRIPQDVSWTSPP--- 5032
Query: 1434 AESLDKNSGPRNRADNSGKPQQPPGGFAPAAINRSIP-CKVIVDHSTTLTSSLSLTVSVE 1492
S+DK S P + + P P+ I+ ++P K+ ++ LTS L +
Sbjct: 5033 --SVDKTSSPSSFLSS-------PAMTTPSLISSTLPEDKLSSPMTSLLTSGLVKITDIL 5083
Query: 1493 SSEASLDLQGRPVRTEASVQPVACPQVSVISRPEPVANEGIDHSSTFIAA--------SA 1544
+ P + S + +A S S+ I+ T + A S
Sbjct: 5084 RTRLEPVTSSLPNFSSTSDKILA---TSKDSKDTKEIFPSINTEETNVKANNSGHESHSP 5140
Query: 1545 AKQDSKTLPATCTSLRELPLVPDKLNEPTAPSHNFAEQA---RGPAPFKS---------- 1591
A DS+T P T + V D + P H +E R P F +
Sbjct: 5141 ALADSET-PKATTQMVITTTVGDPAPSTSMPVHGSSETTNIKREPTYFLTPRLRETSTSQ 5199
Query: 1592 ----EADTTCSNQYNPSNRIC-WNDDGMRSTGQ-PLVTHSGSSKQKEYLEQSCPK----A 1641
DT+ P+ I + G+ S+ + H S+ + P+ +
Sbjct: 5200 ESSFPTDTSFLLSKVPTGTITEVSSTGVNSSSKISTPDHDKSTVPPDTFTGEIPRVFTSS 5259
Query: 1642 IKTEHANYLNVSELHPRNLVTNVALPVKSELHEADKGFRMD-TEDFPGPELPPPAAEGAS 1700
IKT+ A ++ P ++ LP+ + + G T+ FP E+ G
Sbjct: 5260 IKTKSAEMTITTQASPPESASHSTLPLDTSTTLSQGGTHSTVTQGFPYSEVTTLMGMGPG 5319
Query: 1701 SVQQTQNMKASTSSPMEEAISLATDALKRVPGAGSSGCRLSSVEANNPLVTQLLQGNLPL 1760
N+ T+ P+EE S+++ +SS +P P+
Sbjct: 5320 ------NVSWMTTPPVEETSSVSS--------------LMSSPAMTSP---------SPV 5350
Query: 1761 EKVLPQPRLGAKLEINRLPLPLQTTS---VGKTAPERNVEIPPS 1801
PQ + L + LP + T+ +G T+PE PP+
Sbjct: 5351 SSTSPQSIPSSPLPVTALPTSVLVTTTDVLGTTSPESVTSSPPN 5394
Score = 49.3 bits (116), Expect = 4e-05
Identities = 262/1280 (20%), Positives = 463/1280 (36%), Gaps = 130/1280 (10%)
Query: 523 SESPQEEMTVVIDQLEVCDSLIPSTSSMTHVSDTEHKESETAVETSTPKIKTGSSSLEGQ 582
S S EEM + S + + + +S H+ S++ +TS + T S++L+
Sbjct: 1462 STSLTEEMASTDLDISSPSSPMSTFAIFPPMSTPSHELSKSEADTSAIR-NTDSTTLDQH 1520
Query: 583 FPNEGIAIDMELQSDPEEQLSENACISETSFSSESPEGACTSLPSPGGETQSTSEESCTP 642
+ +L + P L+ S S+++ + ++ SP TQS +++ P
Sbjct: 1521 LGIRSLGRTGDLTTVPITPLT-TTWTSVIEHSTQAQDTLSATM-SPTHVTQSLKDQTSIP 1578
Query: 643 ASLETTFCSEVSSTENTDKYNQRNSTDENFHASLMSEIS-PISTSP-EISEASLMSNLPL 700
AS + +EV T + +T F +S I T P I M N
Sbjct: 1579 ASASPSHLTEVYPELGTQGRSSSEAT--TFWKPSTDTLSREIETGPTNIQSTPPMDNTTT 1636
Query: 701 TSEASPV----SNLPL----TSETSPMSDLPLTSETSSVS-----SMLLTSETTFVSSLP 747
S +S V ++LP+ +ETS L S T++VS +L+TS S
Sbjct: 1637 GSSSSGVTLGIAHLPIGTSSPAETSTNMALERRSSTATVSMAGTMGLLVTSAPGRSISQS 1696
Query: 748 LPSETSPISNSSINERMAHQQRKSPSVSEEPLSPQKDESSATAKPLGENLTSQQKNLSNT 807
L +S +S S+ + SP ++ + S++ +P + ++ T
Sbjct: 1697 LGRVSSVLSESTTEGVTDSSKGSSPRLNTQ----GNTALSSSLEPSYAEGSQMSTSIPLT 1752
Query: 808 PEPIIMSSSSIAPEAFPSEDLHNKTLSQQTCKSHVDTEKPYPASIPELASTEMIKVKNHS 867
P I F ++++ ++ KS TE +S L ST + +N
Sbjct: 1753 SSPTTPDVEFIGGSTFWTKEV-TTVMTSDISKSSARTE----SSSATLMSTALGSTENTG 1807
Query: 868 VLQ-RTEKKVLPSP---LELSVFSEGT-DNKGNELPSAKLQDKQYISSVDKAPFSEGSRN 922
+ RT LPSP +E++ + T N N S L + SS
Sbjct: 1808 KEKLRTASMDLPSPTPSMEVTPWISLTLSNAPNTTDSLDLSHGVHTSSAGTLATDRSLNT 1867
Query: 923 KTHKQGSTQSRLETSHTSKSSEPSKSPDGIRNESRDSEISKRKTAEQHSFGICKEKRARI 982
+ ++ +TS S S S E + S E + G +
Sbjct: 1868 GVTRASRLENGSDTSSKSLSMGNSTHTSMTYTEKSEVSSSIHPRPETSAPG----AETTL 1923
Query: 983 EDDQSTRNIS-----SSSPPEK--EQPPREEPRVPPLKIQLSKIGPPFIIKSQPVSKPES 1035
R IS SS P E+ P + + S I PP I+ +
Sbjct: 1924 TSTPGNRAISLTLPFSSIPVEEVISTGITSGPDINSAPMTHSPITPPTIVWT-------- 1975
Query: 1036 RASTSTSVSGGRNTGARTLADIKARAQQARAQREAAAAAAVAAAASIVSG-AMGSPGEGG 1094
ST T + A + + + Q A +A+ S+ SG + SP
Sbjct: 1976 --STGTIEQSTQPLHAVSSEKVSVQTQSTPYVNSVAVSASPTHENSVSSGSSTSSPYSSA 2033
Query: 1095 KTRTL-AHIKEQTKAKLFAKHQARAHLFQTSKETRLPPPLSSKEGPPNLEVSSTPETKME 1153
+L + I + + + T T L LSS + S+T E +
Sbjct: 2034 SLESLDSTISRRNAITSWLWDLTTSLPTTTWPSTSLSEALSSGHSGVSNPSSTTTEFPLF 2093
Query: 1154 GSTGVIIV---NPNCRS--PSNKSAHLRETTTVLQQSLNPSKLPETATDLSVHSSDENIP 1208
+ NP + P N +A +T+ + + + L ET S+ SS+ +P
Sbjct: 2094 SAASTSAAKQRNPETETHGPQNTAA-----STLNTDASSVTGLSETPVGASI-SSEVPLP 2147
Query: 1209 VSHLSEKIVSSTSSENSSVPMLFNKNS--------VPVSVCSTAISGAIKEHPFVSSVDK 1260
++ S VS +SE+++ P L +S + + + +S + + P+ S+
Sbjct: 2148 MAITSRSDVSGLTSESTANPSLGTASSAGTKLTRTISLPTSESLVSFRMNKDPWTVSIPL 2207
Query: 1261 SSVLMSVDSANTTISACNISMLKTIQG--TDTPCIAIIPKCIESTPISATTEGSSISSSM 1318
S + + +++ L T+ DTP S S TE ++IS
Sbjct: 2208 GSHPTTNTETSIPVNSAGPPGLSTVASDVIDTPSDGAESIPTVSFSPSPDTEVTTISHFP 2267
Query: 1319 D-DKQLLISSSSASNLVSTQYTSVPTPSIGNNLPNLSTSSVLIPPMGINNRFPSEKIAIP 1377
+ + SS ++ ++++ T +P + + + T + P + + R A
Sbjct: 2268 EKTTHSFRTISSLTHELTSRVTPIPGDWMSSAMSTKPTGA--SPSITLGERRTITSAAPT 2325
Query: 1378 GSEEQATVSMGTTVRAALSCSDSVAVTDSLVAHPTVAMFTGNMLTINSYDSPPKLSAESL 1437
S T S T +L +V +D L A T N L +S S ++
Sbjct: 2326 TSPIVLTASFTETSTVSLDNETTVKTSDILDARKT------NELPSDSSSSSDLINTSIA 2379
Query: 1438 DKNSGPRNRADNSGKPQQPPGGFAPAAINRSIPCKVIVDHSTTLTSSLSLTVSVESSEAS 1497
A S P G A ++ + + V STT T++ + + SV S+ S
Sbjct: 2380 SSTMDVTKTASIS--PTSISGMTASSSPSLFSSDRPQVPTSTTETNT-ATSPSVSSNTYS 2436
Query: 1498 LDLQGRPVRTEASVQPVACPQVSVISRPEPVANEGIDHSSTFIAASAAKQDSKT------ 1551
LD T +++ P S + + ST ++ A ++ T
Sbjct: 2437 LDGGSNVGGTPSTLPPFTITHPVETSSALLAWSRPVRTFSTMVSTDTASGENPTSSNSVV 2496
Query: 1552 ----LPATCTSL---RELPLVPDKLNEPTAPSHNFAEQARGPA----PFKSEADTTCSNQ 1600
P T TS+ +LP + P +H+ PA P S A T S+
Sbjct: 2497 TSVPAPGTWTSVGSTTDLPAMGFLKTSPAGEAHSLLASTIEPATAFTPHLSAAVVTGSSA 2556
Query: 1601 YNPSNRICWNDD-GMRSTGQ-PLVTHSGSSKQKEYLEQSCPKAIKTEHANYLNVSELHPR 1658
+ ++ + ++ + S+ Q P SG++ + +S + TE ++ S++
Sbjct: 2557 TSEASLLTTSESKAIHSSPQTPTTPTSGANWETSATPESL--LVVTETSDTTLTSKI--- 2611
Query: 1659 NLVTNVAL-------PVKSELHEADKGFRMDTEDFPGPELPPPAAEGASSVQQTQNMKAS 1711
LVT+ L P K G T P +P A E SS+ +
Sbjct: 2612 -LVTDTILFSTVSTPPSKFPSTGTLSGASFPTLLPDTPAIPLTATEPTSSL--------A 2662
Query: 1712 TSSPMEEAISLATDALKRVP 1731
TS +++A+D+L VP
Sbjct: 2663 TSFDSTPLVTIASDSLGTVP 2682
Score = 49.3 bits (116), Expect = 4e-05
Identities = 166/873 (19%), Positives = 317/873 (36%), Gaps = 118/873 (13%)
Query: 545 PSTSSMTHVSDTEHKE-SETAVETSTPKIKTGSSSLEGQFPNEGIAIDMELQSDPEEQLS 603
P TSS ++S T + + T V T T K++ + G P L+
Sbjct: 9195 PETSSPPNLSSTSAEILAITEVTTDTEKLEMTNVVTSGY-----------THESPSSVLA 9243
Query: 604 ENACISETSFSSES-PEG---ACTSLP--SPGGETQSTSEESCTPASLETTFCSEVSSTE 657
++ TS + P G TS P S Q+ S+ S TP +ET+ E SS
Sbjct: 9244 DSVTTKATSSMGITYPTGDTNVLTSTPAFSDTSRIQTKSKLSLTPGLMETSISEETSSAT 9303
Query: 658 NTDKYNQRNSTDENFHASLMSEISPISTSPEISEASLMSNLPLTSEASPVSNLPLTSETS 717
T S IS TS S MS+ + +S E++
Sbjct: 9304 EKSTVLSSVPTGATTEVSRTEAISSSRTSIPGPAQSTMSSDTSMETITRISTPLTRKEST 9363
Query: 718 PMSDLPLTSETSSVSSMLLTSETTFVSSLPLPSETSPISNSSINERMAHQQRKSPSVSEE 777
M+ P T + + S T +++ +S P A QR SV
Sbjct: 9364 DMAITPKTGPSGATSQGTFTLDSSSTASWP-------------GTHSATTQRFPQSVVTT 9410
Query: 778 PLSPQKDESSATAKPLGENLTSQQKNLSNTPEPIIMSSSSIAPE---AFPSEDLHNKTLS 834
P+S + E + PL S +KN + P ++ SSS +P + PS H+
Sbjct: 9411 PMS-RGPEDVSWPSPL-----SVEKN--SPPSSLVSSSSVTSPSPLYSTPSGSSHSS--- 9459
Query: 835 QQTCKSHVDTEKPYPASIPELASTEMIKVKNHSVLQRTEKKVLPSPLELSVFSEGTDNKG 894
P + L ++ M+K + L+ S+ E T
Sbjct: 9460 --------------PVPVTSLFTSIMMKATD--------------MLDASLEPETTSAPN 9491
Query: 895 NELPSAKLQDKQYISSVDKAPFSEGSRNKTHKQGSTQSRLETSHTSKSSEPSK--SPDGI 952
+ S + ++ +A + +H + ++ + S + SEP+K SP
Sbjct: 9492 MNITSDESLAASKATTETEAIHVFENTAASHVETTSATEELYSSSPGFSEPTKVISPVVT 9551
Query: 953 RNESRDSEISKRKTAEQHSFGICK-------EKRARIEDDQSTRNISSSSPPEK---EQP 1002
+ RD+ +S T S GI + + + +++++I+SS+ + P
Sbjct: 9552 SSSIRDNMVS---TTMPGSSGITRIEIESMSSLTPGLRETRTSQDITSSTETSTVLYKMP 9608
Query: 1003 PREEPRVPPLKI----QLSKIGPPFIIKSQPVS-KPESRASTSTSVSGGRNTGARTLADI 1057
P V ++ + S GP S +S + +R STS ++ A+I
Sbjct: 9609 SGATPEVSRTEVMPSSRTSIPGPAQSTMSLDISDEVVTRLSTSPIMTES--------AEI 9660
Query: 1058 KARAQQARAQREAAAAAAVAAAASIVSGAMGSPGEGGKTRTLAHIKEQTKAKLFAKHQAR 1117
Q + + + + + +SG + +G + ++ + L
Sbjct: 9661 TITTQTGYSLATSQVTLPLGTSMTFLSGTHSTMSQGLSHSEMTNLMSRGPESLSWTSPRF 9720
Query: 1118 AHLFQTSKETRLPPPLSSKEGPPNLEVSSTPETKMEGSTGVIIVNPNCRSPSNKSAHLRE 1177
++S P +S + + S+P + + ++ ++ P + E
Sbjct: 9721 VETTRSSSSLTSLPLTTSLSPVSSTLLDSSPSSPLPVTS---LILPGLVKTTEVLDTSSE 9777
Query: 1178 TTTVLQQSLNPSKLPETATDLSVHSSDENIPVSHLSEKIVSSTSSENSSVPMLFNKNSVP 1237
T +L+ + + AT + +++ P S+ + V ++SS + S + +
Sbjct: 9778 PKTSSSPNLSSTSVEIPATSEIMTDTEKIHPSSNTAVAKVRTSSSVHESHSSVLADSETT 9837
Query: 1238 VSVCSTAISGAIKEHPFVSSVDKSSVLMSVDSANTTISACNISMLKTIQGTDTPCIAIIP 1297
+++ S I+ A+ + +S S + + T + +T +T I
Sbjct: 9838 ITIPSMGITSAVDDTTVFTSNPAFSETRRIPTEPT--FSLTPGFRETSTSEETTSITETS 9895
Query: 1298 KCIESTPISATTEGSSISSSMDDKQLLISSSSASNLVSTQYTSVPTPSIGNNLPNLSTSS 1357
+ P SATTE S++ M ++ I S S + T V T +++ + ST
Sbjct: 9896 AVLYGVPTSATTE-VSMTEIMSSNRIHIPDSDQSTMSPDIITEVITRLSSSSMMSESTQM 9954
Query: 1358 VLIPPMGINNRFPSEKIAIPGSEEQATVSMGTT 1390
+ + + + PG+ Q+T+++ TT
Sbjct: 9955 TI-----------TTQKSSPGATAQSTLTLATT 9976
Score = 48.5 bits (114), Expect = 7e-05
Identities = 232/1116 (20%), Positives = 396/1116 (35%), Gaps = 175/1116 (15%)
Query: 469 NHKTIPEFSEEAESLTNSHEEPQIAPPEDNLESCVMMNDVLETL--PHIEVKIEGKSESP 526
N T PE A S +H P E+ S + ++ ET P+I SES
Sbjct: 777 NAATSPERVRNATSPL-THPSPS---GEETAGSVLTLSTSAETTDSPNIHPTGTLTSESS 832
Query: 527 QEEMTVVIDQLEVCDSLIPSTSSMTHVSDTEHKESETA------VETSTPKIKTGSSSLE 580
+ T+ + + + S++ TH+ + + ET+ ETS +++T +S
Sbjct: 833 ESPSTLSLPSVSGVKTTFSSSTPSTHLFTSGEETEETSNPSVSQPETSVSRVRTTLASTS 892
Query: 581 GQFPNEGIAIDMELQSDPEEQLSENACISETSFSSESPEGACTSLPSP------GGETQS 634
P + M+ Q S + +SE +S + T P G T S
Sbjct: 893 VPTP---VFPTMDTWPTRSAQFSSSHLVSELRATSSTSVTNSTGSALPKISHLTGTATMS 949
Query: 635 -----TSEESCTPASLETTFCSEVSSTENTDKYNQRNSTDENFHASLMSE--ISPISTSP 687
T +S P S S T +++ + A++M SP ++S
Sbjct: 950 QTNRDTFNDSAAPQSTTWPETSPRFKTGLPSATTTVSTSATSLSATVMVSKFTSPATSSM 1009
Query: 688 EISEASLMSNLPLTSEAS-------------PVSNLPLTSETSPMSDLPLTSETSSVSSM 734
E + S LT+E + P+ +T S LP+ + SS +SM
Sbjct: 1010 EATSIREPSTTILTTETTNGPGSMAVASTNIPIGKGYITEGRLDTSHLPIGTTASSETSM 1069
Query: 735 LLTSETTFVSSLPLPSETSPISNSSINERMAH-----QQRKSPSVSEEPLSPQKDESSA- 788
T VS PS++ + SS R + S E P+ SSA
Sbjct: 1070 DFTMAKESVSMSVSPSQSMDAAGSSTPGRTSQFVDTFSDDVYHLTSREITIPRDGTSSAL 1129
Query: 789 TAKPLGENLTSQQKNLSNTPEPIIMSSSSIAPEAFPSEDLHNKTLSQQTCKSHV-DTEKP 847
T + + S + + I+SSS +P P + + +Q+ S + DT +
Sbjct: 1130 TPQMTATHPPSPDPGSARSTWLGILSSSPSSPT--PKVTMSSTFSTQRVTTSMIMDTVET 1187
Query: 848 YPASIPELASTEMIKVKNHSVLQRTEKKVL-----PSPLELSVFSEGTDNKGNELPSAKL 902
++P L ST + N K L PSP SEG LP+
Sbjct: 1188 SRWNMPNLPSTTSLTPSNIPTSGAIGKSTLVPLDTPSPATSLEASEG------GLPT--- 1238
Query: 903 QDKQYISSVDKAPFSEGSRNKTHKQGSTQSRLETSHTSKSSEPSKSPDGIRNESRDSEIS 962
+S+ ++ + H + S ++ + S S +P + +S
Sbjct: 1239 -----LSTYPESTNTPSIHLGAHASSESPSTIKLTMASVVKPGSYTPLTFPSIETHIHVS 1293
Query: 963 KRKTAEQHSFGICKEKRARIEDDQSTRNISSSSPPEKEQPPREEPRVPPLKIQLSKIGP- 1021
+ A SS S PE P S P
Sbjct: 1294 TARMA-----------------------YSSGSSPEMTAPGETNTG--------STWDPT 1322
Query: 1022 PFIIKSQPVSKPESRASTSTSVSGGRNTGARTLADIKARAQQARAQREAAAAAAVAAAAS 1081
+I + P ++ ST SV RTL R + + E+A AA + +
Sbjct: 1323 TYITTTDPKDTSSAQVSTPHSV--------RTL-----RTTENHPKTESATPAAYSGSPK 1369
Query: 1082 IVSGA-MGSPGEGGKTRTLAHIKEQTKAKLFAKHQARAHLFQTSKETRLPPPLSSKEGPP 1140
I S + SP K T+ E + + K ++ F+T S GP
Sbjct: 1370 ISSSPNLTSPAT--KAWTITDTTEHSTQLHYTKLAEKSSGFET----------QSAPGPV 1417
Query: 1141 NLEVSSTPE--TKMEGSTGVIIVNPNCRSPSNKSAHLRETTTVLQQSLNPSKLPETATDL 1198
++ + ++P + T + P +PS ++ T L SL ++ T D+
Sbjct: 1418 SVVIPTSPTIGSSTLELTSDVPGEPLVLAPSEQTTITLPMATWLSTSLT-EEMASTDLDI 1476
Query: 1199 SVHSSDENIPVSHLSEKIVSSTSSENSSVPMLFNKNSVPVSVCSTAISGAIKEHPFVSSV 1258
S SS P+S + ST S S K+ S S + +H + S+
Sbjct: 1477 SSPSS----PMSTFAIFPPMSTPSHELS------KSEADTSAIRNTDSTTLDQHLGIRSL 1526
Query: 1259 DKSSVLMSVDSANTTISACNISMLKTIQGTDTPCIAIIPKCI-----ESTPISATTEGSS 1313
++ L +V T + ++ T Q DT + P + + T I A+ S
Sbjct: 1527 GRTGDLTTVPITPLTTTWTSVIEHST-QAQDTLSATMSPTHVTQSLKDQTSIPASASPSH 1585
Query: 1314 I------------SSSMDDKQLLISSSSASNLVSTQYTSV-PTPSIGNNLPNLSTSSVL- 1359
+ SSS S+ + S + T T++ TP + N S+S V
Sbjct: 1586 LTEVYPELGTQGRSSSEATTFWKPSTDTLSREIETGPTNIQSTPPMDNTTTGSSSSGVTL 1645
Query: 1360 -IPPMGINNRFPSE---KIAIPGSEEQATVSMGTTVRAALSCSDSVAVTDSLVAHPTV-A 1414
I + I P+E +A+ ATVSM T+ ++ + +++ SL +V +
Sbjct: 1646 GIAHLPIGTSSPAETSTNMALERRSSTATVSMAGTMGLLVTSAPGRSISQSLGRVSSVLS 1705
Query: 1415 MFTGNMLTINSYDSPPKLSAESLDKNSGPRNRADNSGKPQQPPGGFAPAAINRSIPCKVI 1474
T +T +S S P+L+ + N+ + + S P + + P
Sbjct: 1706 ESTTEGVTDSSKGSSPRLNTQG---NTALSSSLEPSYAEGSQMSTSIPLTSSPTTPDVEF 1762
Query: 1475 VDHSTTLTSSLSLTVSVESSEASLDLQGRPVRTEAS 1510
+ ST T ++ ++ + S++S RTE+S
Sbjct: 1763 IGGSTFWTKEVTTVMTSDISKSS-------ARTESS 1791
Score = 48.1 bits (113), Expect = 9e-05
Identities = 207/1002 (20%), Positives = 364/1002 (36%), Gaps = 160/1002 (15%)
Query: 562 ETAVETSTPKIKTGSSSLEGQFPNEGIAIDMELQSDPEEQLSENACISETSFSSESPEGA 621
+T+ T T I + S+ + P I + S + ++++ SS+SP A
Sbjct: 4025 DTSSTTQTSIISSPGSTAITKGPRTEITSSKRISS---------SFLAQSMRSSDSPSEA 4075
Query: 622 CTSLPSPGGETQS--------TSEESCTPASLETTFCSEVSSTENTDKYNQRNSTDENFH 673
T L + T+S TS T S T S +S T +T + F
Sbjct: 4076 ITRLSNFPAMTESGGMILAMQTSPPGATSLSAPTLDTSATASWTGTPL-----ATTQRFT 4130
Query: 674 ASLMSEISPISTSPEISEASLMSNLPLTSEASPVSNLPLTSETSPMSDLPLTSETSSVSS 733
S + + S PE TS+ SP P ETS S L T+S S+
Sbjct: 4131 YSEKTTL--FSKGPED-----------TSQPSP----PSVEETSSSSSLVPIHATTSPSN 4173
Query: 734 MLLTSETTFVSSLPLPSETSPISNSSINERMAHQQRKSPS-VSEEPLSPQKDESSATAKP 792
+LLTS+ PS T P+++ ++E + S +S EP + S+TA
Sbjct: 4174 ILLTSQG------HSPSSTPPVTSVFLSETSGLGKTTDMSRISLEPGTSLPPNLSSTA-- 4225
Query: 793 LGENLTSQQ-----KNLSNTPEPIIMSSSSIAPEAFPSEDLHNK--TLSQQTCKSHVDTE 845
GE L++ + K + ++ + + + + + E P H K + SH+ +
Sbjct: 4226 -GEALSTYEASRDTKAIHHSADTAVTNMEATSSEYSPIPG-HTKPSKATSPLVTSHIMGD 4283
Query: 846 KPYPASI---PELASTEMIKVKNHSVLQRTEKKVLPSPLELSVF---------------S 887
S+ E E + N + +R+ +V S E S +
Sbjct: 4284 ITSSTSVFGSSETTEIETVSSVNQGLQERSTSQVASSATETSTVITHVSSGDATTHVTKT 4343
Query: 888 EGTDNKGNELPSAKLQDKQYISSVDKAPFSEGSRNKTHKQGSTQSR--LETSHTSKSSEP 945
+ T + G + S Q+I+S + F++ S N + T+S T+ T +
Sbjct: 4344 QATFSSGTSISS----PHQFITSTN--TFTDVSTNPSTSLIMTESSGVTITTQTGPTGAA 4397
Query: 946 SKSPDGIRNESRDSEISKRKTAEQHSFGICKEKRARIEDDQSTRNISSSSPPEKEQPPRE 1005
++ P + + S +++ A F + EK I + +++S +SPP +
Sbjct: 4398 TQGP-YLLDTSTMPYLTETPLAVTPDF-MQSEKTTLI--SKGPKDVSWTSPPSVAETSYP 4453
Query: 1006 EPRVPPLKIQLSKIGPP--FIIKSQPVSKPESRASTSTSVSGGRNTGARTLADIKARAQQ 1063
P L + PP ++ Q S P S S TS T + + Q
Sbjct: 4454 SSLTPFLVTTI----PPATSTLQGQHTSSPVSATSVLTSGLVKTTDMLNTSMEPVTNSPQ 4509
Query: 1064 ARAQREAAAAAAVAAAASI--VSGAMGSPGEGGKTRTLAHIKEQTKAKLFAKHQARAHLF 1121
A +AA I + ++ T + AH+ T A + +
Sbjct: 4510 NLNNPSNEILATLAATTDIETIHPSINKAVTNMGTASSAHVLHSTLPVSSEPSTATSPMV 4569
Query: 1122 QTSKETRLPPPLSSKEGPPNLEVSSTPETKMEGSTGVIIVNPNCRSPSNKSAHLRETTTV 1181
P S + ++ + + T +EG + + + + + + +
Sbjct: 4570 ---------PASSMGDALASISIPGSETTDIEGEPTSSLTAGRKENSTLQEMNSTTESNI 4620
Query: 1182 LQQSLNPSKLPETATDLSVHSSDEN-IPVSHLSEK---IVSSTSSENSSVPMLFNKNSVP 1237
+ +++ + E AT + V S D IP S K I S SS S+ P + S
Sbjct: 4621 ILSNVSVGAITE-ATKMEVPSFDATFIPTPAQSTKFPDIFSVASSRLSNSPPM--TISTH 4677
Query: 1238 VSVCSTAISGAIKEHPFVSSVDKSSVLMSVDSANTTISACNISMLKTIQGTDTPCIAIIP 1297
++ T SGA + P ++D S++ S + + S + T D
Sbjct: 4678 MTTTQTGSSGATSKIPL--ALDTSTLETSAGTPSVVTEGFAHSKITTAMNNDV------- 4728
Query: 1298 KCIESTPISATTEGSSISSSMDDKQLLISSSSASNLVSTQYTSVPTPSIGNNLPNLSTSS 1357
K + T E SS SS +L+++ +S + Q+ S +P +S SS
Sbjct: 4729 KDVSQTNPPFQDEASSPSS---QAPVLVTTLPSSVAFTPQWHSTSSP--------VSMSS 4777
Query: 1358 VLIPPMGINNRFPSEKIAIPGSEEQATVSMGTTVRAALSCSD-----SVAVTDSLVAHPT 1412
VL S + G + + ++ ++ ++ + D S A TD HP+
Sbjct: 4778 VL----------TSSLVKTAGKVDTSLETVTSSPQSMSNTLDDISVTSAATTDIETTHPS 4827
Query: 1413 VAMFTGNMLTINS-YDSPPKLSAESLDKNSGPRNRADNSGKPQQPPGGFAPAAINRSIPC 1471
+ N+ T S ++S +SA P I+RSIP
Sbjct: 4828 INTVVTNVGTTGSAFESHSTVSAYP---------EPSKVTSPNVTTSTMEDTTISRSIPK 4878
Query: 1472 KVIVDHSTTLTSSLSLTVSVESSEASLDLQGRPVRTEASVQP 1513
+ T T+S SLT + + S ++ TE S P
Sbjct: 4879 SSKTTRTETETTS-SLTPKLRETSISQEITS---STETSTVP 4916
Score = 43.5 bits (101), Expect = 0.002
Identities = 259/1318 (19%), Positives = 439/1318 (33%), Gaps = 210/1318 (15%)
Query: 271 TFASLPQHFQQYLLLLLPEVDRQMGSDGILRLSTSALNNEFFAYAAQGWKQRLAEGEFTP 330
T ASL H + +P S + RL TS + + A + L P
Sbjct: 10764 TIASLVTHPEAQTSSAIPT---STISPAVSRLVTSMVTS--LAAKTSTTNRALTNSPGEP 10818
Query: 331 EMQLRIRQEIEKEKKTEPWKEKFFERFYGEKLGMSREESVKLTTGPNNAGAQSSSSCGT- 389
+ + + T PW F F+ + + + +TT + GA+SSS+ T
Sbjct: 10819 ATTVSLVTHPAQTSPTVPWTTSIF--FHSKS-----DTTPSMTT---SHGAESSSAVPTP 10868
Query: 390 ----------SGLPVSAQTALAEQQPKSMKSPASPEPGFCATLCPMVEIPPKDIMAELES 439
+ L S++ ++ P SP PE P + E
Sbjct: 10869 TVSTEVPGVVTPLVTSSRAVISTTIPILTLSPGEPET------------TPSMATSHGEE 10916
Query: 440 EDILIPEESVIQEEIAEEVETSICECQDENHKTIPEFSEEAESLTNSHEEPQIAPPEDNL 499
IP +V + V + + + TIP LT S EP+ P
Sbjct: 10917 ASSAIPTPTV-SPGVPGVVTSLVTSSRAVTSTTIP-------ILTFSLGEPETTPSMATS 10968
Query: 500 ESCVMMNDVLETLPHIEVKIEGKSESPQEEMTVVIDQLEVCDSLIPSTSSMTHVSDTEH- 558
+ V LP + + S + + + L + +T SM T H
Sbjct: 10969 HGTEAGSAVPTVLPEVPGMVTSLVASSRAVTSTTLPTLTLSPGEPETTPSMA----TSHG 11024
Query: 559 KESETAVETSTPKIK-------TGSSSLEGQFPNEGIAIDMELQSDPEEQLSENACISE- 610
E+ + V T +P++ T SS + I EL++ P S A S
Sbjct: 11025 AEASSTVPTVSPEVPGVVTSLVTSSSGVNSTSIPTLILSPGELETTPSMATSHGAEASSA 11084
Query: 611 --TSFSSESPEGACTSLPSPGGETQST--------SEESCTPASLETTFCSEVSS---TE 657
T S G T L + ST S E T S+ T+ E SS T
Sbjct: 11085 VPTPTVSPGVSGVVTPLVTSSRAVTSTTIPILTLSSSEPETTPSMATSHGVEASSAVLTV 11144
Query: 658 NTDKYNQRNSTDENFHASLMSEISPISTSPEISEASLMSNLPLTSEASPVSNLPLTSETS 717
+ + S + A + I ++ S + E + ++L SEA +S +P + +
Sbjct: 11145 SPEVPGMVTSLVTSSRAVTSTTIPTLTISSDEPETT--TSLVTHSEAKMISAIPTLAVSP 11202
Query: 718 PMSDLPLTSETSSVSSMLLTSETTFVSSLPLPSETSPISNSSINERMAHQQRKSPSVSEE 777
+ L + TSS S S T SS P +I+ +AH P
Sbjct: 11203 TVQGLVTSLVTSSGSETSAFSNLTVASSQP----------ETIDSWVAH-----PGTEAS 11247
Query: 778 PLSPQKDESSATAKPLGENLTSQQKNLSNTPEPIIMSSSSIAPEAFPSEDLHNKTLSQQT 837
+ P S+ GE T N+S P SSS P + +
Sbjct: 11248 SVVPTLTVST------GEPFT----NISLVTHP--AESSSTLPRT-----------TSRF 11284
Query: 838 CKSHVDTEKPYPASIPELASTEMIKVKNHSVLQRTEKKVLPSPLELSVFSEGTDNKGNEL 897
S +DT P + PE S+ S + T +P L V S G D
Sbjct: 11285 SHSELDT-MPSTVTSPEAESS--------SAISTTISPGIPGVLTSLVTSSGRDISAT-- 11333
Query: 898 PSAKLQDKQYISSVDKAPF-SEGSRN-KTHKQGSTQSRLETSHTSKSSEPSKSPDGIRNE 955
+V ++P SE + + TH ++ + T+ SEP +P +
Sbjct: 11334 ----------FPTVPESPHESEATASWVTHPAVTSTTVPRTTPNYSHSEPDTTPSIATSP 11383
Query: 956 SRDSEISKRKTAEQHSFGICKEKRARIEDDQSTRNISSSSPPEKEQPPREEPRVPPLKIQ 1015
++ T++ + + + + ++ +S EP I
Sbjct: 11384 GAEA------TSDFPTITVSPDVPDMVTSQVTSSGTDTSITIPTLTLSSGEPETTTSFIT 11437
Query: 1016 LSKIGPPFIIKSQPVSKPESRASTSTSVSGGRN--TGARTLADIKARAQQARAQREAAAA 1073
S+ I + PVS S+ TS +S G + T TL + +
Sbjct: 11438 YSETHTSSAIPTLPVSPGASKMLTSLVISSGTDSTTTFPTLTETPYEPE----------- 11486
Query: 1074 AAVAAAASIVSGAMGSPGEGGKTRTLAHIKEQTKAKLFAKHQARAHLFQTSKETRLPPPL 1133
A ++ A + T +H K T + A T + P +
Sbjct: 11487 ---TTAIQLIHPAETNTMVPRTTPKFSHSKSDTTLPV-AITSPGPEASSAVSTTTISPDM 11542
Query: 1134 SSKEGPPNLEVSSTPETKMEGSTGVIIVNPNCRSPSNKS---AHLRETTTVLQQSL---- 1186
S +L S P + + ST ++ P + H ET+T + ++
Sbjct: 11543 S------DLVTSLVPSSGTDTSTTFPTLSETPYEPETTATWLTHPAETSTTVSGTIPNFS 11596
Query: 1187 ------NPSKLPETATDLSVHSSDENIPVS---HLSEKIVSSTSSENSSVPMLFNKNSVP 1237
PS + D IP S ++ ++ SS + ++++P L P
Sbjct: 11597 HRGSDTAPSMVTSPGVDTRSGVPTTTIPPSIPGVVTSQVTSSATDTSTAIPTLTPSPGEP 11656
Query: 1238 VSVCSTAISGAIKEHPFVSSVDKSSVLMSVDSANTTISACNISMLKTIQGTDTPCIAIIP 1297
+ S+A HP + + S T+++ +T +
Sbjct: 11657 ETTASSA------THPGTQTGFTVPIRTVPSSEPDTMASWVTHPPQTSTPVSRTTSSFSH 11710
Query: 1298 KCIESTPISATTEGSSISSSMDDKQLLISSSSASNLVSTQYTS--------VPTPSIGNN 1349
++TP+ AT+ + SS++ L S A +V++Q TS VPT +
Sbjct: 11711 SSPDATPVMATSPRTEASSAV----LTTISPGAPEMVTSQITSSGAATSTTVPTLTHSPG 11766
Query: 1350 LPNLSTSSVLIPPMGINNRFPSEKIAIPGSEEQATVSMGTTVRAALSCSDSVAVTDSLVA 1409
+P + P + FP+ + SE A++ T+R S +L
Sbjct: 11767 MPETTALLSTHPRTETSKTFPASTVFPQVSETTASL----TIRPGAETS------TALPT 11816
Query: 1410 HPTVAMFTGNMLTINSYDSPPKLSAESLDKNSGPRNRADNSGKPQQPPGGFAPAAINRSI 1469
T ++FT + + D P S + + P + + P + +
Sbjct: 11817 QTTSSLFTLLVTGTSRVDLSPTAS-PGVSAKTAPLSTHPGTETSTMIPTSTLSLGLLETT 11875
Query: 1470 PCKVIVDHSTTLTSSLSLTVS-VESSEASLDLQGRPVRTEASVQPVACPQVSVISRPE 1526
+ T TS+L+LTVS S +S + +T S P V+ + PE
Sbjct: 11876 GLLATSSSAETSTSTLTLTVSPAVSGLSSASITTDKPQTVTSWNTETSPSVTSVGPPE 11933
Score = 42.7 bits (99), Expect = 0.004
Identities = 116/575 (20%), Positives = 197/575 (34%), Gaps = 55/575 (9%)
Query: 1131 PPLSSKEGPPNLEVS--STPETKMEGSTGVIIVNPNCRSPSNK---SAHLRETTTVLQQS 1185
P L+ G P S + ET + + V+P S+ TTT +
Sbjct: 11420 PTLTLSSGEPETTTSFITYSETHTSSAIPTLPVSPGASKMLTSLVISSGTDSTTTFPTLT 11479
Query: 1186 LNPSKLPETATDLSVHSSDENIPVSHLSEKIVSSTSSENSSVPMLFNKNSVPVSVCSTAI 1245
P + PET +H ++ N V + K S S ++PV++ S
Sbjct: 11480 ETPYE-PETTAIQLIHPAETNTMVPRTTPKFSHSKSD-----------TTLPVAITSPGP 11527
Query: 1246 SGAIKEHPFVSSVDKSSVLMS-VDSANTTISACNISMLKTIQGTDTPCIAIIPKCIESTP 1304
+ S D S ++ S V S+ T S ++ +T +T + ST
Sbjct: 11528 EASSAVSTTTISPDMSDLVTSLVPSSGTDTSTTFPTLSETPYEPETTATWLTHPAETSTT 11587
Query: 1305 ISATTEGSSISSSMDDKQLLISSSSASNLVSTQYTSVPTPSIGNNLPNLSTSSVLIPPMG 1364
+S T S S D +++S T++P PSI + + TSS
Sbjct: 11588 VSGTIPNFSHRGS-DTAPSMVTSPGVDTRSGVPTTTIP-PSIPGVVTSQVTSSATDTSTA 11645
Query: 1365 INNRFPS--EKIAIPGSEEQATVSMGTTVRAALSCSDSVAVTDSLVAHP----TVAMFTG 1418
I PS E S G TV S S V HP T T
Sbjct: 11646 IPTLTPSPGEPETTASSATHPGTQTGFTVPIRTVPSSEPDTMASWVTHPPQTSTPVSRTT 11705
Query: 1419 NMLTINSYDSPPKLSAESLDKNSGPRNRADNSGKPQQPPGGF--APAAINRSIP------ 1470
+ + +S D+ P ++ + S + G P+ + AA + ++P
Sbjct: 11706 SSFSHSSPDATPVMATSPRTEASSAVLTTISPGAPEMVTSQITSSGAATSTTVPTLTHSP 11765
Query: 1471 -----CKVIVDHSTTLTSSL--SLTVSVESSEASLDLQGRPVRTEASVQPVACPQ----- 1518
++ H T TS + TV + SE + L RP ++ P
Sbjct: 11766 GMPETTALLSTHPRTETSKTFPASTVFPQVSETTASLTIRPGAETSTALPTQTTSSLFTL 11825
Query: 1519 -VSVISRPE--PVANEGIDHSSTFIAASAAKQDSKTLPATCTSLRELPLVPDKLNEPTAP 1575
V+ SR + P A+ G+ + ++ + S +P + SL L L ++
Sbjct: 11826 LVTGTSRVDLSPTASPGVSAKTAPLSTHPGTETSTMIPTSTLSLGLLE-TTGLLATSSSA 11884
Query: 1576 SHNFAEQARGPAPFKSEADTTCSNQYNPSNRICWNDD---GMRSTGQPLVTHSGSSKQKE 1632
+ + +P S + P WN + + S G P + + +
Sbjct: 11885 ETSTSTLTLTVSPAVSGLSSASITTDKPQTVTSWNTETSPSVTSVGPPEFSRTVTGTTMT 11944
Query: 1633 YLEQSCPKAIKTEHANYLNVSELHPRNLV--TNVA 1665
+ P KT H ++ + + +V TN+A
Sbjct: 11945 LIPSEMPTPPKTSHGEGVSPTTILRTTMVEATNLA 11979
Score = 38.5 bits (88), Expect = 0.075
Identities = 195/927 (21%), Positives = 336/927 (36%), Gaps = 173/927 (18%)
Query: 482 SLTNSHEEPQIAPPEDNLESCVMMNDVLETLPHIEVKIEGKSESPQEEMTVVIDQ---LE 538
+LT + + E N + TL +E + + EMT +
Sbjct: 403 ALTTTSPSTTLVSEETNTHHSTSGKETEGTLNTSMTPLETSAPGEESEMTATLVPTLGFT 462
Query: 539 VCDSLI--PSTSSMTHV--------SDTEHKESETAVETSTPKIK--TGSSSLEGQFPNE 586
DS I PS S +H S + + S TA S+ ++ T S+S + +E
Sbjct: 463 TLDSKIRSPSQVSSSHPTRELRTTGSTSGRQSSSTAAHGSSDILRATTSSTSKASSWTSE 522
Query: 587 GIAIDMELQSDPEE-QLSENACISETSFSSESPEGAC---TSLPS--PGGETQSTSEESC 640
A S+P+ Q E + +T S A TS+PS G T TS
Sbjct: 523 STAQQF---SEPQHTQWVETSPSMKTERPPASTSVAAPITTSVPSVVSGFTTLKTS---- 575
Query: 641 TPASLETTFCSEVSSTENTDKYNQRNSTDENFHASLMSEISPISTSPEISEASLMSNLPL 700
S + + E S+ + +T + + +S ST L++
Sbjct: 576 ---STKGIWLEETSADTLIGESTAGPTTHQFAVPTGISMTGGSSTRGSQGTTHLLTRATA 632
Query: 701 TSEASPVSNLPLTSETSPMSDLPLTSETSSVSSMLLTSETTFVSSLPLPSETSPISNSSI 760
+SE S ++L L + P+S P S+T++ SS ++ ++ + ETS + +S+
Sbjct: 633 SSETS--ADLTLATNGVPVSVSPAVSKTAAGSSPPGGTKPSYTMVSSVIPETSSLQSSAF 690
Query: 761 NERMAHQQRKSPSVSEEPLSPQKDESSATAKPLGENLTSQQKNLSNTPEPIIMSSSSIAP 820
R+ S+ PL+ + SS G S T P++ S+S +
Sbjct: 691 --------REGTSLGLTPLNTRHPFSSPEPDSAGHTKIS-------TSIPLLSSASVLED 735
Query: 821 EAFPSEDL--HNKTLSQQTCKSHVDTE-KPYPASIPEL----ASTEMIKVKNHSVLQRTE 873
+ + H T S T + T+ KP A + + A+T +V+N T
Sbjct: 736 KVSATSTFSHHKATSSITTGTPEISTKTKPSSAVLSSMTLSNAATSPERVRN-----ATS 790
Query: 874 KKVLPSP---------LELSVFSEGTDNKGNELPSAKLQDKQYISSVDKAPFSEGSRNKT 924
PSP L LS +E TD+ N P+ L + S + S T
Sbjct: 791 PLTHPSPSGEETAGSVLTLSTSAETTDSP-NIHPTGTLTSESSESPSTLSLPSVSGVKTT 849
Query: 925 HKQGSTQSRLETS--HTSKSSEPSKSPDGIRNESRDSEISKRKTAEQHSFGICKEKRARI 982
+ + L TS T ++S PS S ++ +S+ +T
Sbjct: 850 FSSSTPSTHLFTSGEETEETSNPSVS-------QPETSVSRVRT---------------- 886
Query: 983 EDDQSTRNISSSSPPEKEQPPREEPRVPPLKIQLSKIGPPFIIKSQPVSKPESRASTSTS 1042
++S+S P P + P Q S S VS E RA++STS
Sbjct: 887 -------TLASTSVPTPVFPTMD--TWPTRSAQFS--------SSHLVS--ELRATSSTS 927
Query: 1043 VSGGRNTGARTLADIKARAQQARAQREAAAAAAVAAAASIVSGAMGSPGEGGKTRTLAHI 1102
V+ + ++ + A ++ R+ +A ++ T
Sbjct: 928 VTNSTGSALPKISHLTGTATMSQTNRDTFNDSAAP-----------------QSTTWPET 970
Query: 1103 KEQTKAKLFAKHQARAHLFQTSKETRLPPPLSSKEGPPNLEVSSTPETKMEGSTGVIIVN 1162
+ K L S T + +S + ++P T +T +
Sbjct: 971 SPRFKTGL------------PSATTTVSTSATSLSATVMVSKFTSPATSSMEATSI---- 1014
Query: 1163 PNCRSPSNKSAHLRETTTVLQQSLN-PSKLPETATDLSV---HSSDENIPVSHLSEKIVS 1218
R PS TT + ++ N P + +T++ + + ++ + SHL +
Sbjct: 1015 ---REPS--------TTILTTETTNGPGSMAVASTNIPIGKGYITEGRLDTSHLP---IG 1060
Query: 1219 STSSENSSVPMLFNKNSVPVSVC-STAISGAIKEHPFVSS--VDK-SSVLMSVDSANTTI 1274
+T+S +S+ K SV +SV S ++ A P +S VD S + + S TI
Sbjct: 1061 TTASSETSMDFTMAKESVSMSVSPSQSMDAAGSSTPGRTSQFVDTFSDDVYHLTSREITI 1120
Query: 1275 SACNISMLKTIQGTDTPCIAIIPKCIESTPISATTEGSSISSSMDDKQLLISSSSASNLV 1334
S T Q T T + P ST + S S S ++ +SS+ ++ V
Sbjct: 1121 PRDGTSSALTPQMTATHPPSPDPGSARSTWLGIL----SSSPSSPTPKVTMSSTFSTQRV 1176
Query: 1335 STQYTSVPTPSIGNNLPNLSTSSVLIP 1361
+T + N+PNL +++ L P
Sbjct: 1177 TTSMIMDTVETSRWNMPNLPSTTSLTP 1203
Score = 37.0 bits (84), Expect = 0.22
Identities = 110/572 (19%), Positives = 202/572 (35%), Gaps = 127/572 (22%)
Query: 511 TLPHIEVKIEGKSESPQEEMTVVIDQLEVCDSLIPSTSSMTH-----VSDTEHKESETAV 565
TLP ++ S T+ D ++ SL+PS+ + T +S+T ++ TA
Sbjct: 11517 TLPVAITSPGPEASSAVSTTTISPDMSDLVTSLVPSSGTDTSTTFPTLSETPYEPETTAT 11576
Query: 566 ETSTPKIKTGSSSLEGQFPNEGIAIDMELQSDPEEQLSENACISETSFSSESPEGACTSL 625
+ P S+++ G PN FS + A + +
Sbjct: 11577 WLTHPA--ETSTTVSGTIPN---------------------------FSHRGSDTAPSMV 11607
Query: 626 PSPGGETQSTSEESCTPASLETTFCSEVSSTENTDKYNQRNSTDENFHASLMSEISPIST 685
SPG +T+S + P S+ S+V+S ++TD ++ + ++P
Sbjct: 11608 TSPGVDTRSGVPTTTIPPSIPGVVTSQVTS----------SATDT---STAIPTLTPSPG 11654
Query: 686 SPEISEASLMSNLPLTSEASPVSNLPLTSETSPMSDLPLTSETSSVSSMLLTSETTFVSS 745
PE + +S T P+ +P +SE +++S + T S
Sbjct: 11655 EPETTASSATHPGTQTGFTVPIRTVP-------------SSEPDTMASWVTHPPQT---S 11698
Query: 746 LPLPSETSPISNSSINERMAHQQRKSPSVSEEPLSPQKDESSATAKPLGENLTSQQKNLS 805
P+ TS S+SS + +P ++ P + T P + + Q S
Sbjct: 11699 TPVSRTTSSFSHSSPD--------ATPVMATSPRTEASSAVLTTISPGAPEMVTSQITSS 11750
Query: 806 NTPEPIIMSSSSIAPEAFPSEDLHNKTLSQQTCKSHVDTEKPYPAS--IPELASTEMIKV 863
++S+ P S + T T +T K +PAS P+++ T
Sbjct: 11751 GA------ATSTTVPTLTHSPGMPETTALLST-HPRTETSKTFPASTVFPQVSETTASLT 11803
Query: 864 KNHSVLQRTEKKVLPSPLELSVFS-----------EGTDNKGNELPSAKLQDKQYISSVD 912
T LP+ S+F+ T + G +A L +
Sbjct: 11804 IRPGAETST---ALPTQTTSSLFTLLVTGTSRVDLSPTASPGVSAKTAPLSTHPGTETST 11860
Query: 913 KAPFSEGSRNKTHKQG--STQSRLETSHTSKSSEPSKSPDGIRNESRDSEISKRKTAEQH 970
P S S G +T S ETS ++ + S + G+ + S ++
Sbjct: 11861 MIPTSTLSLGLLETTGLLATSSSAETSTSTLTLTVSPAVSGLSSASITTD---------- 11910
Query: 971 SFGICKEKRARIEDDQSTRNISSSSPPEKEQP---------PREEPRVPPLKIQLSKIGP 1021
K + + +++ +++S PPE + P E P PP + P
Sbjct: 11911 -----KPQTVTSWNTETSPSVTSVGPPEFSRTVTGTTMTLIPSEMP-TPPKTSHGEGVSP 11964
Query: 1022 PFIIKSQPVSKPESRASTSTSVSGGRNTGART 1053
I+++ V +T+ + +G T A+T
Sbjct: 11965 TTILRTTMVE------ATNLATTGSSPTVAKT 11990
Score = 35.8 bits (81), Expect = 0.49
Identities = 106/504 (21%), Positives = 191/504 (37%), Gaps = 63/504 (12%)
Query: 362 LGMSREESVKLTTGPNNAGAQSSSSCGTSGLPVSAQTALAEQQP---------------- 405
L +S +++ TGP+ + + TS + SA T A Q
Sbjct: 6147 LTISTHKTIATQTGPSGVTSLGQLTLDTSTIATSAGTPSARTQDFVDSETTSVMNNDLND 6206
Query: 406 --KSMKSPASPEPGFCATLCPMVEIPPKDIMAELE--SEDILIPEESVIQEEIAE--EVE 459
K+ A + +V P + + L+ S L+ SV +A+ +++
Sbjct: 6207 VLKTSPFSAEEANSLSSQAPLLVTTSPSPVTSTLQEHSTSSLVSVTSVPTPTLAKITDMD 6266
Query: 460 TSICECQDENHKTIPEFSEEAESLTNSHE-EPQIAPPEDNLESCVMMNDVLETLPHIEVK 518
T++ E + + + +E+ T++H P I N+ + N+ T+
Sbjct: 6267 TNL-EPVTRSPQNLRNTLATSEATTDTHTMHPSINTAVANVGTTSSPNEFYFTV------ 6319
Query: 519 IEGKSESPQEEMTVVIDQLEVCDSLIPSTSSMTHVSDTEHKESETAV-------ETSTPK 571
P + + V+ DS++ ++SM S + ESET ETST +
Sbjct: 6320 --SPDSDPYKATSAVVITSTSGDSIV--STSMPRSSAMKKIESETTFSLIFRLRETSTSQ 6375
Query: 572 IKTGSSSLEGQFPNEGIAIDMELQSDPEEQLSENACISETSFSSESPEGAC---TSLPSP 628
K GSSS ++ S E S I T + SP+ + T L +
Sbjct: 6376 -KIGSSSDTSTVFDKAFTAATTEVSRTELTSSSRTSIQGTEKPTMSPDTSTRSVTMLSTF 6434
Query: 629 GGETQSTSEESCTP-----ASLETTFCSEVSSTEN--------TDKYNQRN-STDENFHA 674
G T+S T A+ + T + S T + T ++Q + ST +
Sbjct: 6435 AGLTKSEERTIATQTGPHRATSQGTLTWDTSITTSQAGTHSAMTHGFSQLDLSTLTSRVP 6494
Query: 675 SLMSEISPISTSPEISEASLMSNLPLTSEASPV-SNLPLTSETSPMSDLPLTSETSSVSS 733
+S SP S S +SL+S LP + SPV + LP + +SP+ L + ++
Sbjct: 6495 EYISGTSPPSVEKTSSSSSLLS-LPAITSPSPVPTTLPESRPSSPVHLTSLPTSGLVKTT 6553
Query: 734 MLLTSETTFVSSLPLPSETSPISNSSINERMAHQQRKSPSVSEEPLSPQKDESSATAKPL 793
+L S + +L S P ++ I + + +V+ + + ES ++
Sbjct: 6554 DMLASVASLPPNLGSTSHKIPTTSEDIKDTEKMYPSTNIAVTNVGTTTSEKESYSSVPAY 6613
Query: 794 GE--NLTSQQKNLSNTPEPIIMSS 815
E +TS N + I+ +S
Sbjct: 6614 SEPPKVTSPMVTSFNIRDTIVSTS 6637
>gi|239740773 PREDICTED: similar to diffuse panbronchiolitis critical
region 1 [Homo sapiens]
Length = 1400
Score = 77.0 bits (188), Expect = 2e-13
Identities = 242/1249 (19%), Positives = 437/1249 (34%), Gaps = 157/1249 (12%)
Query: 360 EKLGMSREESVKLTTGPNNAGAQSSSSCGTSGLPVSAQTALAEQQPKSMKSPASPEPGFC 419
+K G E+S+ + + ++++S SG + Q + + + K A+ + +
Sbjct: 245 DKTGRPLEKSMSTLDKTSTSSHKTTTSFHNSGNSQTKQKSTSFPE----KITAASKTTYK 300
Query: 420 ATLCPMVEIPPKDIMAELESEDILIPEESVIQEEI-AEEVETSICECQDENHKTIPEFSE 478
T P +D + S+ +L IQE I A E+ S+ E + +T
Sbjct: 301 TTGTPEESEKTEDSRTTVASDKLLTKTTKNIQETISANELTQSLAEPTEHGGRT------ 354
Query: 479 EAESLTNSHEEPQIAPPEDNLESCVMMNDVLETLPHIEVKIEGKSESPQEEMTVVIDQLE 538
N + P A P +N E N L E + +E+ + E
Sbjct: 355 -----ANENNTPSPAEPTENRERTANENTTLSPAEPTENRERTANENTAPFPAGPTENRE 409
Query: 539 VCDSLIPSTSSMTHVSDTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMELQSDP 598
+ + +++ TEH E TA E +TP ++P
Sbjct: 410 MTAN---ENTTLFPAEPTEHGE-RTANENTTPS-----------------------PAEP 442
Query: 599 EEQLSENACISETSFSSESPEGACTSLPSPGGETQSTSEESC-----TPASLETTFCSEV 653
E E T+ S P P +T S+S ES TP + E T S
Sbjct: 443 TEH-GERTANENTTPSPAEPTEHGERTPFANDKTTSSSAESTEHGERTPLANENTTPSPA 501
Query: 654 SSTENTDKYNQRNST------DENFHASLMSEISPISTSPEISEASLMSNLPLTSEASPV 707
TEN ++ N+T EN + + + P + + + S A P
Sbjct: 502 EPTENRERTANENTTPSPAGPTENRETTANEKTTLSPVEPTENRETTANEKTTPSPAEPT 561
Query: 708 SNLPLTSETSPMSDLPLTSETSSVSSMLLTSETTFVSSLPLPSETSPISNSSINERMAHQ 767
N + +P ++ TS SS T + PS P N ER A+
Sbjct: 562 EN----GQRTPFANEKTTS--SSAEPTEHGERTPLANENTTPSPAEPTEN---RERTAN- 611
Query: 768 QRKSPSVSEEPLSPQKDESSATAKPLGENLTSQQKNLSNTPEPIIMSSSSIAPEAFPSED 827
++ +PS +E + D + + +L +N TP + + + A P+E
Sbjct: 612 EKTTPSPAEP--TENGDRTPLANEKTTPSLAEPTENGQRTP---FANEKTTSSSAEPTEH 666
Query: 828 LHNKTLSQQTCKSHVDTEKPYPASIPELASTEMIKVKNHSVLQRTEKKVLPSPLELSVF- 886
L+ + P PA E + S TE + + + + ++F
Sbjct: 667 EERTPLAN-------ENTTPSPAEPTENRERTANENTTPSPAGPTENREMTANEKTTLFP 719
Query: 887 SEGTDNKGNELPSAKLQDKQYISSVDKAPFSEGSRNKTHKQGSTQSRLE-TSHTSKSSEP 945
+E T+N+ + + +S P G R + +T S E T H ++ P
Sbjct: 720 AEPTENR-------ERTANEKTTSSPAEPTENGQRTPFANEKTTSSSAEPTEHGERT--P 770
Query: 946 SKSPDGIRNESRDSEISKRKTAEQHSFGICKEKRARIEDDQSTRNISSSSPPEKEQPPRE 1005
+ + + + +E ++ +TA + + E E R + ++ P QP
Sbjct: 771 LANENTTLSPAGPTE-NRERTANEKTTPFPAEPTENRE-----RTANENTTPSPAQPTEN 824
Query: 1006 EPRVPPL--KIQLSKIGPPFIIKSQPVSKPESRASTSTSVSGGRNTGARTLADIKARAQQ 1063
R P K S P K P + ++ +S++ T + A+
Sbjct: 825 GDRTPLANEKTTPSLAEPTENGKRTPFANEKTTSSSAEPTEHAERTPLANENTTSSPAEP 884
Query: 1064 ARAQREAAAAAAVAAAASIVSGAMGSPGEGGKTRTLAHIKEQTKAKLFAKHQARAHLFQT 1123
+ A A + E K F +
Sbjct: 885 TENRERTANEKTTQFPAEPTENRESTANE--------------KTTPFPAEPTENREWTA 930
Query: 1124 SKETRLPP--PLSSKEGPPNLEVSSTPETKMEGSTG------VIIVNPNCRSPSNKSAHL 1175
++ T L P P +E P + + +GS V S S+ ++ +
Sbjct: 931 NENTTLSPAEPTEHEEMTPLMVDENLQAPFRQGSCAERPKDICATVASTTGSESSTASEI 990
Query: 1176 RETTTVLQQSLNPSKLPETATDLSVHSSDENIPVSHLSEKIV--SSTSSENSSVPMLFNK 1233
++T+ + S TA+++++ S+ IPVS + + + S+ SE + +L +
Sbjct: 991 ITSSTMSVSATASSTASSTASEITMSSA--AIPVSSTAYETIRFSTAVSEPVTASILALE 1048
Query: 1234 NSVP-VSVCSTAISGAIKEHPFVSSV--DKSSVLMSVDSANTTISACNISMLKTIQGTDT 1290
+++ +V +T S + P +S K++ + TTI+A S T+ T T
Sbjct: 1049 STLAFTTVSNTTTSSTVTSVPTTASTSGSKNTTACEATMSETTIAAITASEDTTV-STQT 1107
Query: 1291 PCIAI--IPKCIESTPISATTEGSSISSSMDDKQLLISS--SSASNLVSTQYTSVPTPSI 1346
IA +P TP TT S + ++ +I+S S+A N S T+ +
Sbjct: 1108 SVIAAESVPHTATKTPTDTTTASVSATVPKNNTLSVITSTPSTAPNTASKTMTTASKTTT 1167
Query: 1347 GNNLPNLSTS-SVLIPPMGINNRFPSEKIAIPGSEEQATVSMGTTVRAALSCSDSVAVTD 1405
+ + +L T+ + + P+ + +T + GTTV +A S +
Sbjct: 1168 TSTITSLPTTVFTTTSKITAGSEIPTASTTDSATTAISTKASGTTVESAPSTAPPTPAET 1227
Query: 1406 SLVAHPTVAMFTGNMLTINSYDS--PPKLSAESLDKNSGPR-NRADNS------------ 1450
+ + PT TG+ T + S P + A + + ++G RA S
Sbjct: 1228 TTASVPTTTSTTGSENTGHHTVSSVPTTVFATASESSTGSETTRASTSATEVTTAMTTAM 1287
Query: 1451 --GKPQQPPGGFAPAAINRSIPCKVIVDHSTTLTSSLSLTVSVESSEASLDLQGRPVRTE 1508
G AP +S V + T T+S+S T S + ++D + V T
Sbjct: 1288 TTGSETAVVSTKAPVTTTQSGFSTATVMPAKTTTASVSTTASTTLYQNTIDSVAKSVPTM 1347
Query: 1509 ASV---------QPVACPQVSVISRPEPVANEGIDHSSTFIAASAAKQD 1548
S + V+ P I PE I +S + + A D
Sbjct: 1348 DSTIASKSTTLSKIVSVPTAVFIKAPETTTGSEITLASIITSGTTAVCD 1396
>gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo
sapiens]
Length = 2036
Score = 75.9 bits (185), Expect = 4e-13
Identities = 190/878 (21%), Positives = 304/878 (34%), Gaps = 119/878 (13%)
Query: 546 STSSMTHVSDTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMELQSDPEEQLSEN 605
+T ++ S T + S + ET+ T ++S+ G+ P S P +
Sbjct: 779 TTPGLSEESTTVYSSSRGSTETTVFPHST-TTSVHGEEPTT-------FHSRPAS--THT 828
Query: 606 ACISETSFSSESPEGACTSLPSPGGETQSTSEESCTPASL---ETTFCSEVSSTENTDKY 662
+E S +S E + T+ P TQ+ + T A L TTF S ST K
Sbjct: 829 TLFTEDSTTSGLTEES-TAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGT--KL 885
Query: 663 NQRNSTDENFHASLMSEISPISTSPEISEASLMSNLPLTSEASPVSNLPLTSETSPMSDL 722
+ ST + L+ E +P SP +E + + P T S S TS SP + L
Sbjct: 886 SPARSTT----SGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATL 941
Query: 723 -PLTSETSSVSSMLLTSE----TTFVSSLPLPSETSPISNSSINERMAHQQRKSPSVSEE 777
P T+ +S VS TS +T ++ P + TS +S S +E
Sbjct: 942 SPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTT------SHSSQGSTEA 995
Query: 778 PLSPQKDESSATAKPLGENLTSQQKNLSNT-----PEPIIMSS----------------S 816
LSP S TA LG+ T+ + +T P+ I S +
Sbjct: 996 TLSP----GSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHT 1051
Query: 817 SIAPEAFPSEDLHNKTLSQQTCKSHVDTEKPYPASIPELASTEMIKVKNHSVLQRT---- 872
++ P + S L ++ + Q+ S DT P + A+ + HS T
Sbjct: 1052 TLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGT---TAAPVEVSTTYHSRPSSTPTTH 1108
Query: 873 ---EKKVLPSPLELSVFSEGTDNKGNELPSAKLQDKQYISSVDKAPFSEGSRNKTHKQGS 929
L E + G L + + +P S GS T GS
Sbjct: 1109 FSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGS 1168
Query: 930 TQSR-LETSHTSKSSEPSKSPDGIRN--ESRDSEISKRKTAEQHSFGICKEKRARIEDDQ 986
T + L T+ S P +SPD + + S +S+ T G
Sbjct: 1169 TTTAGLSEKSTTFYSSP-RSPDTTLSPASTTSSGVSEESTTSHSRPG--STHTTAFPGST 1225
Query: 987 STRNISSSSPPEKEQPPREEPRVPPLKIQLSKIGP-PFIIKSQPVSKPESRASTSTSVSG 1045
+ +S S P + + P S +GP S P S + +T+ SG
Sbjct: 1226 TMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASG 1285
Query: 1046 --------GRNTGA--RTLADIKARAQQARA-------QREAAAAAAVAAAASIVSGAMG 1088
+TG+ TL+ + +Q + + A ++ V +
Sbjct: 1286 LLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTT 1345
Query: 1089 SPGEGGKTRTLAHIKEQTKAKLFAKHQARAHLFQTSKETRLPPPLSSKEGPPNLEVSSTP 1148
S G T T H + ++ H + T P S+ G L ST
Sbjct: 1346 SHGSPSSTPT-THFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSG---LVEESTA 1401
Query: 1149 ETKMEGSTGVI----IVNPNCRSPSNKSAHLRETTTVLQQSLNPSKLPETATDLSVHSSD 1204
GST + + RS ++++H T T+ S L E T S HSS
Sbjct: 1402 YHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPT--SYHSSP 1459
Query: 1205 ENIPVSHLSEKIVSSTSSENSSVPMLF-NKNSVPVSVCSTAISGAIKEHPFVSSVDKSSV 1263
+I +H E +S SE S+ + N + SG I E ++
Sbjct: 1460 GSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAE--------STTF 1511
Query: 1264 LMSVDSANTTISACNISMLKTIQGTDTPCIAIIPKCIESTPISATTEGSSISSSMDDKQL 1323
+S S TT+++ TP ++ + ++ + IS S L
Sbjct: 1512 YISPGSMETTLAST----------ATTPGLSAKSTILYTSDLVGEPTTFYISPSPTYTTL 1561
Query: 1324 LISSSSASNLVSTQYTSVPTPSIGNNLPNLSTSSVLIP 1361
+SSS S L T +PS + + + + L P
Sbjct: 1562 FPASSSTSGLTEESTTFHTSPSFTSTIVSTESLETLAP 1599
Score = 72.0 bits (175), Expect = 6e-12
Identities = 232/1139 (20%), Positives = 382/1139 (33%), Gaps = 164/1139 (14%)
Query: 545 PSTSSMTHVSDTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMELQSDPEEQLSE 604
PS+ TH+S + VE ST + S+ FP EE +
Sbjct: 295 PSSIPTTHIS--ARSTTSGLVEESTTYHSSPGSTQTMHFPESDTT-----SGRGEESTTS 347
Query: 605 NACISETSFSSESPEGACTSLPSPGGETQSTSEESCTPASLETTFCSEVSSTENTDKYNQ 664
++ + T S+ S A P+ + ++ + P S T+ SE E+T ++
Sbjct: 348 HSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSE----ESTASHSS 403
Query: 665 RNSTDENF--HASLMSEISPISTSPEISEASLMSN-LPLTSEASPVSNLPLTSETSPMSD 721
+++T S S + ST+ IS S+ + LP ++ +S T +SP S
Sbjct: 404 QDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSP 463
Query: 722 LPLTSETSSVSSMLLTSETTFVSSLPLPSETSPISNSSIN---ERMAHQQRKSPSVSEEP 778
S S+ SS ++ E+T S P + T+ +S+ R + SP ++
Sbjct: 464 ATTLSPASTTSSG-VSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTT 522
Query: 779 LSPQK------------------------DESSATAKPLGENLTSQQKNLSNTPEPIIMS 814
L P S TA G+ T+ N +T +
Sbjct: 523 LLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPD 582
Query: 815 SSSIAPEAFPSEDLHNKTLSQQTCKSHVDTEKPYPASIPELASTEMIKVKNHSVLQRTEK 874
S++ + S +H+ T S +T T P ++ P L E + H T
Sbjct: 583 STTSSGIVEASTRVHSSTGSPRT------TLSPASSTSPGLQG-ESTAFQTHPASTHT-- 633
Query: 875 KVLPSPLELSVFSEGTDNKGNELPSAKLQDKQYISSVDKAPFSEGSRNKTHKQGSTQSRL 934
PSP PS + ++ ++P GS TH S+ +
Sbjct: 634 --TPSP-----------------PSTATAPVEESTTYHRSP---GSTPTTHFPASSTT-- 669
Query: 935 ETSHTSKSSEPSKSPD--GIRNESRDSEISKRKTAEQHSFGICKEKRARIEDDQSTRNIS 992
+ H+ KS+ SPD G S S S R + + + +T +S
Sbjct: 670 -SGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLS 728
Query: 993 SSSPPEKEQPPREEPRVPPLKIQLSKIGPPFII-KSQPVSKPESRASTSTSVSGGRNTGA 1051
+S P + P + +G +SQP S + + ST+ G
Sbjct: 729 EASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEEST 788
Query: 1052 RTLADIKARAQQARAQREAAAAAAVAAAASIVSGAMGSPGEGGKTRTLAHIKEQTKAKLF 1111
+ + + ++ + + G + T T LF
Sbjct: 789 TVYSSSRGSTE-----------------TTVFPHSTTTSVHGEEPTTFHSRPASTHTTLF 831
Query: 1112 AKHQARAHLFQTSKETRLP-PPLSSKEGPP------NLEVSSTPETKMEGSTGVIIVNPN 1164
+ + L T + T P P S++ G P +L ST GSTG +
Sbjct: 832 TEDSTTSGL--TEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPAR 889
Query: 1165 C--------RSPSNKSAHLRETTTVLQQSLNPSKLPETATDL--SVHSSDENIPVSHLSE 1214
+PS S ETTT+ PS L E +T S S D + + +
Sbjct: 890 STTSGLVGESTPSRLSPSSTETTTLPGSPTTPS-LSEKSTTFYTSPRSPDATLSPATTTS 948
Query: 1215 KIVSSTSSENSSVPMLFNKNSVPVSVCSTAISGAIKEHPFVSSVDKSSVLMSVDSANTTI 1274
VS SS + S P + + P S ++ +S + P S + S ++ +TT
Sbjct: 949 SGVSEESSTSHSQPGSTHTTAFPDSTTTSDLS----QEPTTSHSSQGSTEATLSPGSTTA 1004
Query: 1275 SACNISMLKTIQGT--DTPCIAIIPKCIESTPISATTEGSSISSSMDDKQLLISSSSAS- 1331
S+ T + DT + I S + A+T S + S+ SS+SA
Sbjct: 1005 SSLG-QQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGL 1063
Query: 1332 NLVSTQYTSVPTPSIGNNLP--------NLSTSSVLIPPMGINNRFPSEKIAIPGSEEQA 1383
ST + S P+ S P +ST+ P F + + SEE
Sbjct: 1064 QEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEEST 1123
Query: 1384 TV--SMGTTVRAALSCSDSVAV----------------TDSLVAHPTVAMFTGNMLTINS 1425
TV S G T A + +V T +L T A + T S
Sbjct: 1124 TVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYS 1183
Query: 1426 YD-------SPPKLSAESLDKNSGPRNRADNSGKPQQPPGGFAPAAINRSIPCKVIVDHS 1478
SP ++ + + S + S PG +++ S
Sbjct: 1184 SPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGS 1243
Query: 1479 TTLTSSLSLTVSVESSEASLDLQGRPVRTEASVQPVACPQVSVISRPEPV-ANEGIDHSS 1537
T T S T + S P TE ++ P ++ PV ++ G H++
Sbjct: 1244 TDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTT 1303
Query: 1538 TFIAASAAKQDSKTLPATCTSLRELPLVPDKLNEPTAPSHNFAEQARGPAPFKSEADTT 1596
A S +Q T+ + P D + P + F E + S TT
Sbjct: 1304 LSPAGSTTRQGES------TTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTT 1356
Score = 68.2 bits (165), Expect = 9e-11
Identities = 227/1095 (20%), Positives = 366/1095 (33%), Gaps = 175/1095 (15%)
Query: 548 SSMTHVSDTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMELQSDPEEQLSENAC 607
S + S H + T P T S + P+ + ME + P
Sbjct: 61 SGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPGLS 120
Query: 608 ISETSFSSESPEGACTSLP----SPGGETQSTSEESCTPASLETTFCSEVS----STENT 659
T+F S T LP S G +ST+ S ++ T F + S E+T
Sbjct: 121 EKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQEST 180
Query: 660 DKYNQRNSTDENFHASLMSEISPISTS--------------PEISEASLMSNLPLTSEAS 705
++ TD + +SP ST+ P +E +L LP + AS
Sbjct: 181 ASHSSPGPTD--------TTLSPGSTTASSLGPEYTTFHSRPGSTETTL---LPDNTTAS 229
Query: 706 PV--SNLPLTSET-SPMSDLPLTSETSSVSSMLLTSETTFVSSLPLPSETSPISNSSINE 762
+ +++P+ S T SP + L S S E+T S P +T P ++ +
Sbjct: 230 GLLEASMPVHSSTRSPHTTL------SPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSA 283
Query: 763 RMAHQQRKSPSVSEEPLSPQKDESSATAKPLGENLTSQQKNLSNT-----PEPIIMSSSS 817
+ S S P + + +T L E T+ + +T PE S
Sbjct: 284 FVEPSTTSHGSPSSIPTT--HISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRG 341
Query: 818 IAPEAFPSEDLHNKTLSQQTCKSHVDTEKPYPASIPELASTEMIKVKNHSVLQRTEKKVL 877
S H + + T + V+ Y +S A+T + + R+E
Sbjct: 342 EESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHF--PDSSTTSGRSE---- 395
Query: 878 PSPLELSVFSEGTDNKGNELPSAKLQDKQYISSVDKAPFSEGSRNKTHKQGST-----QS 932
E + D G + A+ + +P S GS T GST
Sbjct: 396 ----ESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSE 451
Query: 933 RLETSHTS-KSSEPSKSPDGIRNE--SRDSEISKRKTAEQHSFGICKEKRARIEDDQSTR 989
R T H+S +S + SP + S +S S+ + H+ D +T
Sbjct: 452 RSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHT--------TAFPDSTTTP 503
Query: 990 NISSSSPPEKEQPPREEPRVPPLKIQLSKIGPPFIIKSQPVSKPESRASTSTSVSGGRNT 1049
+S S P + + P S GP + + S ST T++S G T
Sbjct: 504 GLSRHSTTSHSSPGSTDTTLLPASTTTS--GP----SQESTTSHSSSGSTDTALSPGSTT 557
Query: 1050 G-----ARTLADIKARAQQARAQREAAAAAAVAAAASIVSGAMGSPGEGGKTRTLAHIKE 1104
T + ++ ++ + A++ V + GSP +
Sbjct: 558 ALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGL 617
Query: 1105 QTKAKLFAKHQARAHLFQTSKETRLPPPLSSKEGPPNLEVSSTPETKMEGSTGVIIVNPN 1164
Q ++ F H A H P P S+ P ST + GST P
Sbjct: 618 QGESTAFQTHPASTH--------TTPSPPSTATAPVE---ESTTYHRSPGST------PT 660
Query: 1165 CRSP--SNKSAHLRETTTVLQQSLNPSKLPETATDLSVHSSDENIPVSHLSEKIVSSTSS 1222
P S S H E +T+ S + S T S HS+ S E S S
Sbjct: 661 THFPASSTTSGH-SEKSTIFHSSPDAS----GTTPSSAHST-----TSGRGESTTSRISP 710
Query: 1223 ENSSVPMLFNKNSVPVSVCSTAISGAIKEHPFVSSVDKSSVLMSVDSANTTISACNISML 1282
++ + ++P S + +S A ++ S S TT+S +++ L
Sbjct: 711 GSTEI------TTLPGSTTTPGLSEA-----------STTFYSSPRSPTTTLSPASMTSL 753
Query: 1283 KTIQGTDTPCIAIIPKCIEST--PISATTEGSSISSSMDDKQLLISSSSASNLVSTQYTS 1340
G ++ P ST P S TT G + ++ + SSS + +T +
Sbjct: 754 GV--GEESTTSRSQPGSTHSTVSPASTTTPG------LSEESTTVYSSSRGSTETTVFPH 805
Query: 1341 VPTPSIGNNLPN------LSTSSVLIPPMGINNRFPSEKIAIPGSEEQATVSMGTTVRAA 1394
T S+ P ST + L + E A PGS S T + A
Sbjct: 806 STTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGS----PASTQTGLPAT 861
Query: 1395 LSCSDSVAVTDSLVAHPTVAMFTGNMLTINSYDSPPKLSAESLDKNSGPRNRADNSGKPQ 1454
L+ +D + + P+ + TG L SP + + L S P + +S +
Sbjct: 862 LTTAD---LGEESTTFPSSSGSTGTKL------SPARSTTSGLVGESTPSRLSPSSTETT 912
Query: 1455 QPPGGFAPAAINRSIPCKVIVDHSTTLTSSLSLTVSVESSEASLDLQGRPVRTEASVQPV 1514
PG +++ S T S + T S SE S +P T + P
Sbjct: 913 TLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPD 972
Query: 1515 ACPQVSVISRPEPVANEGIDHSSTFIAASAAKQDSKTLPATCTSLRELP------LVPDK 1568
+ + P ST S + +L T+ P L+PD
Sbjct: 973 STTTSDLSQEP---TTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDD 1029
Query: 1569 -----LNEPTAPSHN 1578
L E + P+H+
Sbjct: 1030 TITSGLVEASTPTHS 1044
Score = 67.8 bits (164), Expect = 1e-10
Identities = 224/1071 (20%), Positives = 374/1071 (34%), Gaps = 131/1071 (12%)
Query: 546 STSSMTHVSDTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMELQSDPEEQLSEN 605
ST+ TH + T S + T+ + T G P P +
Sbjct: 621 STAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHF---------PASSTTSG 671
Query: 606 ACISETSFSSESPEGACTSLPSPGGETQSTSEESCTPASLETTFCSEVSSTENTDKYNQR 665
T F S SP+ + T+ S T E + + S +T + + + T ++
Sbjct: 672 HSEKSTIFHS-SPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEA 730
Query: 666 NSTDENFHASLMSEISPIS-TSPEISEASLMSNLPLTSEASPVSNLPLTSETSPMSDLPL 724
++T + S + +SP S TS + E S S S S VS P ++ T +S+
Sbjct: 731 STTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVS--PASTTTPGLSEEST 788
Query: 725 TSETSSVSSMLLT------------SETTFVSSLPLPSETSPISNSSINERMAHQQRKSP 772
T +SS S T E T S P + T+ + S + + P
Sbjct: 789 TVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFP 848
Query: 773 SVSEEPLSPQKD-ESSATAKPLGENLTSQQKNLSNTP---EPIIMSSSSIAPEAFPSEDL 828
P S Q ++ T LGE T+ + +T P ++S + E+ PS
Sbjct: 849 G---SPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSR-- 903
Query: 829 HNKTLSQQTCKSHVDTEKPYPASIPELASTEMIKVKNHSVLQRTEKKVLPSPLELSVFSE 888
LS + ++ P S+ E ++T ++ T + +S S
Sbjct: 904 ----LSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDA---TLSPATTTSSGVSEESS 956
Query: 889 GTDNKGNELPSAKLQDKQYISSVDKAPF----SEGSRNKTHKQGST--QSRLETSHTSKS 942
+ ++ + D S + + P S+GS T GST S + S T S
Sbjct: 957 TSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHS 1016
Query: 943 SEPSKSPDGIRNESRDSEISKRKTAEQHSFGI-------CKEKRARIEDDQSTRNISSSS 995
S + +++ S + + T S G A ++++ +T SS
Sbjct: 1017 SPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSS 1076
Query: 996 PPEKEQPPREEPRVPPLKIQLSKIGPPFIIKSQPVSKPESRASTSTSVSGGRNTGARTLA 1055
PP P+++ + S+P S P + S S++ G
Sbjct: 1077 SDTTPSPPGTT--AAPVEVSTT-------YHSRPSSTPTTHFSASSTTLG---------- 1117
Query: 1056 DIKARAQQARAQREAAAAAAVA------AAASIVSGAMGSPGEGGKTRTLAHIKEQTKAK 1109
R++++ + A A A + +V SP G T T A T A
Sbjct: 1118 ----RSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAG 1173
Query: 1110 LFAKHQARAHLFQTSKETRLPPPLSSKEGPPNLEVSS------TPETKMEGSTGVIIVNP 1163
L K + S +T L P ++ G +S T T GST + V+
Sbjct: 1174 LSEK-STTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQ 1232
Query: 1164 NCRSPSNKSAHLRETTTVLQQSLNPSKL-PETATDLSVHSSDENIPVSHLSEKIVSSTSS 1222
S ++ S+ TT+ S S L PE+ T HSS + + L + +S
Sbjct: 1233 E--STASHSSPGSTDTTLSPGSTTASSLGPESTT---FHSSPGSTETTLLPDNTTASGLL 1287
Query: 1223 ENSSVPMLFNKNSVPVSVCSTAISGAIKEHPFVSSVDKSSVLMSVDSANTTISACNISML 1282
E +S P+ + S ++ + E S S M A T ++ + +
Sbjct: 1288 E-ASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMP---APPTTTSAFVELS 1343
Query: 1283 KTIQGTDTPCIAIIPKCIESTPISATTEGSSISSSMDDKQLLISSSSASNLVSTQYTSVP 1342
T G+ + STP TT S+ S+++ + S++ S+ V+T T P
Sbjct: 1344 TTSHGSPS-----------STP---TTHFSASSTTLGRSEE--STTVHSSPVATATTPSP 1387
Query: 1343 TPSIGNNLPNLSTSSVLIPPMGINNRFPSEKIAIPGSEEQATVSMGTTVRAALSCSDSVA 1402
S + L ST+ P FP A SEE T TT + S +
Sbjct: 1388 ARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTT----HTISSPPS 1443
Query: 1403 VTDSLVAHPTVAMFTGNMLTINSYDSPPKLSAESLDKNSGPRNRADNSGKPQQPPGGFAP 1462
T +LV PT + + + S S ++++ + D +G P
Sbjct: 1444 TTSALVEEPTSYHSSPGSIATTHFPESSTTSGRS-EESTASHSSPDTNGITPLPAHFTTS 1502
Query: 1463 AAINRSIPCKVIVDHSTTLTSSLSLTVSVESSEASL---DLQGRPVRTEASVQPVACPQV 1519
I S + T +S + T + + L DL G P S P
Sbjct: 1503 GRIAESTTFYISPGSMETTLASTATTPGLSAKSTILYTSDLVGEPTTFYISPSPTYTTLF 1562
Query: 1520 SVISRPEPVANEGIDHSSTFIAASAAKQDSKTLPATCTSLRELPLVPDKLN 1570
P + G+ ST S + + T+ +T + P P+KLN
Sbjct: 1563 -----PASSSTSGLTEESTTFHTSPS--FTSTIVSTESLETLAPETPEKLN 1606
Score = 61.6 bits (148), Expect = 8e-09
Identities = 141/650 (21%), Positives = 229/650 (35%), Gaps = 69/650 (10%)
Query: 395 SAQTALAEQQPKSMKSPASPEPGFCATL--CPMVEIPPKDIMAELESEDILIPEESVIQE 452
S + L E+ SPAS + G ATL + E + + L P S
Sbjct: 835 STTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSG 894
Query: 453 EIAEEVETSICECQDE-----NHKTIPEFSEEAESLTNSHEEPQ--IAPPEDNLESCVMM 505
+ E + + E T P SE++ + S P ++P
Sbjct: 895 LVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEE 954
Query: 506 NDVLETLP---HIEVKIEG--KSESPQEEMTVVIDQLEVCDSLIP---STSSMTHVSDTE 557
+ + P H + S+ QE T Q +L P + SS+ S T
Sbjct: 955 SSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTF 1014
Query: 558 HKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMELQSDPEEQLSENACISETSFSSES 617
H T P S +E P + P S +A + E S + +S
Sbjct: 1015 HSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPAS--STSAGLQEESTTFQS 1072
Query: 618 PEGACTSLPSPGGETQSTSEESCT----PASLETTFCSEVSST-----ENTDKYNQRNST 668
+ + PSP G T + E S T P+S TT S S+T E+T ++ +T
Sbjct: 1073 WPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGAT 1132
Query: 669 DENFHASLMSE---ISPISTSPEISEASLMSNLPLTSEASPVSNLPLTSETSPMSDLPLT 725
+ + + +TSP S ++ + LP ++ + +S T +SP S
Sbjct: 1133 GTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTL 1192
Query: 726 SETSSVSSMLLTSETTFVSSLPLPSETSPISNSSINERMAHQ---QRKSPSVSEEPLSPQ 782
S S+ SS ++ E+T S P + T+ S+ ++ + SP ++ LSP
Sbjct: 1193 SPASTTSSG-VSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSP- 1250
Query: 783 KDESSATAKPLGENLTSQQKNLSNTPEPIIMSSSSIAPEAFPSEDLHNKTLSQQTCKSHV 842
S TA LG T+ + +T ++ +++ + S +H+ T S T
Sbjct: 1251 ---GSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHT----- 1302
Query: 843 DTEKPYPASIPELASTEMIKVKNHSVLQRTEKKVLPSPLELSVFSEGTDNKGNELPSAKL 902
T P ++ + ST + + +ELS S G+
Sbjct: 1303 -TLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSP----------- 1350
Query: 903 QDKQYISSVDKAPFSEGSRNKTHKQGSTQSRLETSHTSKSSEPSKS-PDGIRNESRDSEI 961
SS FS S + ST T+ + P++S G+ ES
Sbjct: 1351 ------SSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHS 1404
Query: 962 SKRKTAEQH----SFGICKEKRARIEDDQSTRNISSSSPPEKEQPPREEP 1007
S T H S + + +R +T I SSPP EEP
Sbjct: 1405 SPGSTQTMHFPESSTASGRSEESRTSHSSTTHTI--SSPPSTTSALVEEP 1452
Score = 39.3 bits (90), Expect = 0.044
Identities = 165/848 (19%), Positives = 275/848 (32%), Gaps = 151/848 (17%)
Query: 916 FSEGSRNKTHKQGSTQSRLETSHTSKSSEPSKSPDGIRNESRDSEISKRKTAEQHSFGIC 975
F E S H + S T+HT KSS PS + + + S S + +T
Sbjct: 3 FPESSTTSGHSEESATFHGSTTHT-KSSTPSTTA-ALAHTSYHSSLGSTETTH------- 53
Query: 976 KEKRARIEDDQSTRNISSSSPPEKEQPPREEPRVPPLKIQLSKIGPPFIIKSQPVSKPES 1035
D + S S P V P P ++ P S
Sbjct: 54 ------FRDSSTISGRSEESKASHSSPDAMATTVLPAG------STPSVLVGDSTPSPIS 101
Query: 1036 RASTSTSVSGGRNTGARTLADIKARAQQARAQREAAAAAAVAAAASIVSGAMGSPGEGGK 1095
S T+ G T L++ + + A ++ + + S G
Sbjct: 102 SGSMETTALPGSTTKPG-LSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGS 160
Query: 1096 TRTLAHIKEQTKAKLFAKHQARAHLFQTSKETRLPP--PLSSKEGPPNLEVSSTPETKME 1153
T T A T L ++ +H +T L P +S GP S P
Sbjct: 161 THTTAFPGSTTMPGL-SQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRP----- 214
Query: 1154 GSTGVIIVNPNCR----------------------SPSNKSAHLRETTTVLQ--QSLNPS 1189
GST ++ N SP+ + E+TT S +
Sbjct: 215 GSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTR 274
Query: 1190 KLPETATDLSV------HSSDENIPVSHLSEKIVSSTSSENSSVPMLFNKNSVPVSVCST 1243
P T T V H S +IP +H+S + +S E S+ ++ +
Sbjct: 275 PAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTT---YHSSPGSTQTMHF 331
Query: 1244 AISGAIKEHPFVSSVDKSSVLMSVDSANTTISACNISMLKTIQGTDTPCIAIIPKCIEST 1303
S S+ SS ++ SA +T SA + P S+
Sbjct: 332 PESDTTSGRGEESTTSHSSTTHTISSAPSTTSA----------------LVEEPTSYHSS 375
Query: 1304 PISATT---EGSSISSSMDDKQLLISSSSASNLVSTQYTSVPTPSIGNNLPNLSTSSVLI 1360
P S T SS +S ++ S++S S+ +T +P S + L ST+S +
Sbjct: 376 PGSTATTHFPDSSTTSGRSEE----STASHSSQDATGTIVLPARSTTSVLLGESTTSPIS 431
Query: 1361 PPMGINNRFPSEKIAIPGSEEQATV------SMGTTVRAALSCSDSVAVTDSLVAHPTVA 1414
P PG E++T S TT+ A + S V+ + T
Sbjct: 432 SGSMETTALPG-STTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEEST-----TSR 485
Query: 1415 MFTGNMLTINSYDS--PPKLSAESLDKNSGPRNRADNSGKPQQPPGGFAPAAINRSIPC- 1471
G+ T DS P LS S +S P + PA+ S P
Sbjct: 486 SRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTT----------LLPASTTTSGPSQ 535
Query: 1472 KVIVDHSTTLTSSLSL----TVSVESSEASLDLQGRPVRTEASVQPVACPQVSVISRPEP 1527
+ HS++ ++ +L T ++ + S P T ++ P+
Sbjct: 536 ESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTL------------FPDS 583
Query: 1528 VANEGIDHSSTFIAASAAKQDSKTLPATCTSLRELPLVPDKLNEPTAPSHNFAEQARGPA 1587
+ GI +ST + +S + PA+ TS P E TA + A P+
Sbjct: 584 TTSSGIVEASTRVHSSTGSPRTTLSPASSTS-------PGLQGESTAFQTHPASTHTTPS 636
Query: 1588 PFKSEADTTCSNQYNPSNRICWNDDGMRSTGQPLVTHSGSSKQKEYLEQSCPKAIKTEHA 1647
P +T + S + +T P + + +K + S P A T +
Sbjct: 637 P-----PSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPS 691
Query: 1648 NYLNVSELHPRNLVTNVALPVKSELHEADKGFRMDTEDFPGPELPPPAAEGASSVQQTQN 1707
+ + + + + ++ P +E+ PG P +E +++ +
Sbjct: 692 SAHSTTSGRGESTTSRIS-PGSTEI-----------TTLPGSTTTPGLSEASTTFYSSPR 739
Query: 1708 MKASTSSP 1715
+T SP
Sbjct: 740 SPTTTLSP 747
>gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c [Homo
sapiens]
Length = 958
Score = 75.9 bits (185), Expect = 4e-13
Identities = 152/753 (20%), Positives = 270/753 (35%), Gaps = 66/753 (8%)
Query: 381 AQSSSSCGTSGLPVSAQTALAEQQPKSMKSPA---SPEPGFCATLCPMVE---IPPKDIM 434
+ SS G P + + +SPA +P PG + P V+ +PP
Sbjct: 204 SSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRA 263
Query: 435 AELESEDILIPEESVIQEEIAEEVETSICECQDENHKTIPEFSEEAESLTNSHEEPQIAP 494
+ E E E S +EE + + E + S A+ P AP
Sbjct: 264 KKPEEESESSEEGSESEEEAPAGTRSQVKA--SEKILQVRAASAPAKGTPGKGATP--AP 319
Query: 495 PEDNLESCVMMNDVLETLPHIEVKIEGKSESPQEEMTVVIDQLEVCDSLIPSTSSMTHVS 554
P ++ + + P + + + S EE T L + +S +
Sbjct: 320 PG---KAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKAL--LQAKASGKTSQVGAA 374
Query: 555 DTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMELQSDPEEQLSENACISETSFS 614
KES P KTG + + Q + + QS EE SE ++ S
Sbjct: 375 SAPAKESPRKGAAPAPPGKTGPAVAKAQAGKR----EEDSQSSSEESDSEEEAPAQAKPS 430
Query: 615 SESPEGACTSLP---SPGGETQSTSEESCTPASLETTFCSEVSSTENTDKYNQRNSTDEN 671
++P+ S P SP PA+ + + + ++ + + +S E
Sbjct: 431 GKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSE--ESDSDREA 488
Query: 672 FHASLMSEISPISTSPEISEASLMSNLPLTSEASPVSNLPLTSETSPMSDLPLTSETSSV 731
A +++ P+ SP++ AS M PL A PV + T P + + E S
Sbjct: 489 LAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPAT-PSAQVGKWEEDSES 547
Query: 732 SSMLLTSETTFVSSLPLPSETSPISNSSINERMAHQQRKSPSVSEEPLSPQKDESSATAK 791
SS E++ S +P+ +P S+ + + SP+ + K
Sbjct: 548 SS----EESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEK 603
Query: 792 PLGENLTSQQKNLSNTPE--PIIMSSSSIAP-------EAFPSEDLHNKTLSQQTCKSHV 842
P+ + +S++ + S E P M+++ P +A P + N T S + V
Sbjct: 604 PMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKT--NTTASAKVAPVRV 661
Query: 843 DTEKPYPA--------SIPELASTEMIKVKNHSVLQRTEKKVLPSPLELSVFSEGTDNKG 894
T+ P A S P +A ++ S + ++ + + L ++V + KG
Sbjct: 662 GTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKG 721
Query: 895 NELPSAKLQDKQYISSVDKAPFSEGSRNKTHKQGSTQSRLETSHTSKSSEPSKSPDGIRN 954
++ +A + K + AP G T TQ + E S+SSE +
Sbjct: 722 LQVKAASVPVKGSLGQ-GTAPVLPGKTGPT----VTQVKAEKQEDSESSEEESDSEEAAA 776
Query: 955 ESRDSEISKRKTAEQHSFGICKEKRARIEDDQSTRNISSSS-----PPEKEQPPREEPRV 1009
+ S +KT + + + A+ + +++++ P K +PP P+
Sbjct: 777 SPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQN 836
Query: 1010 PPL----KIQLSKIGPPFIIKSQPVSKPESRASTSTSVSGGRNTGARTLADIK--ARAQQ 1063
+ + +G +Q + PE + +S S A TLA +K + Q
Sbjct: 837 STVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEE-AETLAQVKPSGKTHQ 895
Query: 1064 ARAQREAAAAAAVAAAASIVSGAMG-SPGEGGK 1095
RA A + AA G G S + GK
Sbjct: 896 IRAALAPAKESPRKGAAPTPPGKTGPSAAQAGK 928
Score = 40.4 bits (93), Expect = 0.020
Identities = 183/973 (18%), Positives = 331/973 (34%), Gaps = 164/973 (16%)
Query: 631 ETQSTSEESCTPASLETTFCSEVSSTENTDKYNQRNSTDENFHASLMSEISPISTSPEIS 690
E + S + C A T + + T + ++ +E+ A+L ++ + +S S
Sbjct: 29 EVKEQSGQKCFLAQ-PVTLLDIYTHWQQTSELGRKRKAEED--AALQAKKTRVSDPISTS 85
Query: 691 EASLMSNLPLTSEASPVSNLPLTSETSPMSDLPLTSETSSVSSMLLTSETTFVSSLPLPS 750
E+S A L T+ + +DLP + + + + +T +S+P P+
Sbjct: 86 ESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTG--NSMPHPA 143
Query: 751 ETSPISNSSINERMAHQQRKSPSVSEEPLSPQKDESS-----ATAKP----LGENLTSQQ 801
++N + + ++ PS + +S ++E S A AKP G+ +S +
Sbjct: 144 TGKTVAN--LLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSE 201
Query: 802 KNLSNTPEPIIMSSSSIAPEAFPSEDLHNKTLSQQTCKSHVDTEKPYPASIPELASTEMI 861
S++ E + S+ P K S T +S P P + ++ T +
Sbjct: 202 DTSSSSDETDVEGKPSVKPAQV-------KASSVSTKESPARKAAPAPGKVGDV--TPQV 252
Query: 862 KVKNHSVLQRTEKKVLPSPLELSVFSEGTDNKGNELPSAKLQDKQYISSVDKAPFSEGSR 921
K +R +K P E S SE E P+ + + + +
Sbjct: 253 KGGALPPAKRAKK-----PEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPA 307
Query: 922 NKTHKQGSTQSRLETSHTSKSSEPSKSPDGIRNESRDSEISKRKTAEQHSFGICKEKRAR 981
T +G+T + + S + P+ DSE S ++++ + +
Sbjct: 308 KGTPGKGATPAPPGKAGAVASQTKAGKPE------EDSESSSEESSDSEEETPAAKALLQ 361
Query: 982 IEDDQSTRNISSSSPPEKEQPPREEPRVPPLKIQLSKIGPPFIIKSQPVSKPESRASTST 1041
+ T + ++S P KE P + PP K GP + K+Q + E S+S
Sbjct: 362 AKASGKTSQVGAASAPAKESPRKGAAPAPP-----GKTGPA-VAKAQAGKREEDSQSSSE 415
Query: 1042 SVSGGRNTGARTLADIKARAQQARAQREAAAAAAVAAAASIVSGAMGSPGEGGKTRTLAH 1101
A+ A +A Q RA A+A A + A P + G
Sbjct: 416 ESDSEEEAPAQ--AKPSGKAPQVRA------ASAPAKESPRKGAAPAPPRKTGPAAAQVQ 467
Query: 1102 IKEQTKAKLFAKHQARAHLFQTSKETRLPPPLSSKEGPPNLEVSSTPETKMEGSTGVIIV 1161
+ +Q + +R+ ++ + +++ + P + +P+ K + G+
Sbjct: 468 VGKQ-------EEDSRSSSEESDSDREALAAMNAAQVKP---LGKSPQVKPASTMGM--- 514
Query: 1162 NPNCRSPSNKSAHLRETTTVLQQSLNPSKLPETATDLSVHSSDENIPVSHLSEKIVSSTS 1221
P K A + P K+ V +E+ S +S
Sbjct: 515 -----GPLGKGAG----------PVPPGKVGPATPSAQVGKWEED-----------SESS 548
Query: 1222 SENSSVPMLFNKNSVPVSVCSTAISGAIKEHPFVSSVDKSSVLMSVDSANTTISACNISM 1281
SE SS + VP +V +KS L ++ A T S
Sbjct: 549 SEESSDS---SDGEVPTAVAPAQ--------------EKS--LGNILQAKPTSSPAKGPP 589
Query: 1282 LKTIQGTDTPCIAIIPKCIESTPISATTEGSSISSSMDDKQLLISSSSASNLVSTQYTSV 1341
K +A+ K + S ++E SS S+ ++ ++++ A + T
Sbjct: 590 QKAGP------VAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKA 643
Query: 1342 PTPSIGNNLPNLSTSSVLIPPMGINNRFPSEKIAIPGSEEQATVSMGTTVRAALSCSDSV 1401
P N +T+S + P+ + + P + + G T R A S S
Sbjct: 644 -CPKKTN-----TTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSE 697
Query: 1402 AVTDSLVAHPTVAMFTGNMLTINSYDSPPKLSAESLDKNSGPRNRADNSGKPQQPPGGFA 1461
+DS +A+ G ++ + S P + G PG
Sbjct: 698 E-SDSEEEKTGLAVTVGQAKSVGK--------GLQVKAASVPVKGSLGQGTAPVLPGKTG 748
Query: 1462 PAAINRSIPCKVIVDHSTTLTSSLSLTVSVESSEASLDLQGRPVRTEASVQPVACPQVSV 1521
P +V + SS + S E++ + ++ +T+A P A S
Sbjct: 749 PTVT------QVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSA 802
Query: 1522 ---ISRPEPVANEGIDHSSTFIAASAAKQDSKTLPATCTSLRELPLVPDKLNEPTAPSHN 1578
IS P V AA+ AKQ S P K+ P N
Sbjct: 803 KGTISAPGKVVT----------AAAQAKQRS----------------PSKVKPPVRNPQN 836
Query: 1579 FAEQARGPAPFKS 1591
ARGPA S
Sbjct: 837 STVLARGPASVPS 849
Score = 35.0 bits (79), Expect = 0.83
Identities = 108/570 (18%), Positives = 190/570 (33%), Gaps = 110/570 (19%)
Query: 496 EDNLESCVMMNDV--LETLPHIEVKIE-GKSESPQEEMTVVIDQLEVCDSLIPSTSSMTH 552
E + + C + V L+ H + E G+ +E+ + + V D + S SS
Sbjct: 32 EQSGQKCFLAQPVTLLDIYTHWQQTSELGRKRKAEEDAALQAKKTRVSDPISTSESS--- 88
Query: 553 VSDTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMELQSDPEEQLSENACISETS 612
E +E+E +TP++ + +SS+ G +D + E A
Sbjct: 89 ---EEEEEAEAETAKATPRLASTNSSVLG--------------ADLPSSMKEKA-----K 126
Query: 613 FSSESPEGACTSLPSPG-GETQSTSEESCTPASLETTFCSEVSSTENTDKYNQRNSTDEN 671
+E S+P P G+T + +P R S + +
Sbjct: 127 AETEKAGKTGNSMPHPATGKTVANLLSGKSP----------------------RKSAEPS 164
Query: 672 FHASLMSEISPISTSPEISEASLMSNLPLTSEASPVSNLPLTSETSPMSDLPLTSETSSV 731
+ +L+SE + P A+ + S + +S+ + + P
Sbjct: 165 ANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVK 224
Query: 732 SSMLLTSETTFVSSLPLPSETSPISNSSINERMAHQQRKSPSVSEEPLSPQKDESSATAK 791
+S + T E+ + P P + + +P V L P K K
Sbjct: 225 ASSVSTKESPARKAAPAPGKVGDV---------------TPQVKGGALPPAK----RAKK 265
Query: 792 PLGENLTSQQKNLSNTPEPIIMSSSSIAPEAFPSEDLHNKTLSQQTCKSHVDTEKPYPA- 850
P E+ +S++ + S P S A E K L + + PA
Sbjct: 266 PEEESESSEEGSESEEEAPAGTRSQVKASE---------KILQVRAASA--------PAK 308
Query: 851 SIPELASTEMIKVKNHSVLQRTEKKVLPSPLELSVFSEGTDNKGNELPSAK--LQDKQYI 908
P +T K +V +T+ E S SE + + E P+AK LQ K
Sbjct: 309 GTPGKGATPAPPGKAGAVASQTKAGKPEEDSESS--SEESSDSEEETPAAKALLQAKASG 366
Query: 909 SSVDKAPFSEGSRNKTHKQGSTQSRLETSHTSKSSEPSKSPDGIRNESRDSEISKRKTAE 968
+ S ++ K + +T ++ K + ++ S +S+ + A+
Sbjct: 367 KTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQ 426
Query: 969 QHSFGICKEKRARIEDDQSTRNISSSSPPEKEQPPREEPRVPPLKIQLSKIGPPFIIKSQ 1028
G + RA +S P KE P + PP K GP
Sbjct: 427 AKPSGKAPQVRA-------------ASAPAKESPRKGAAPAPP-----RKTGPAAAQVQV 468
Query: 1029 PVSKPESRASTSTSVSGGRNTGARTLADIK 1058
+ +SR+S+ S S A A +K
Sbjct: 469 GKQEEDSRSSSEESDSDREALAAMNAAQVK 498
Score = 32.3 bits (72), Expect = 5.4
Identities = 42/198 (21%), Positives = 79/198 (39%), Gaps = 20/198 (10%)
Query: 38 QKEGLKETSGTSP-----LACLNAMLHTNTRIGDGTFFKIPGKSG-----LYALKKEESS 87
+K GL T G + L A + +G GT +PGK+G + A K+E+S
Sbjct: 704 EKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSE 763
Query: 88 CPADGTLDLVCESELDGTDMAEANAHGEENGVCSKQVTDEASSTRDSSLTNTAVQSKLVS 147
E E D + A + A + + ++ + A++ S+ + K+V+
Sbjct: 764 SS---------EEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVT 814
Query: 148 SFQQHTKKALKQALRQQQKRRNGVSMMVNK-TVPRVVLTPLKVSDEQSDSPSGSESKNGE 206
+ Q +++ + + +N + +VP V + Q+ S S E
Sbjct: 815 AAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEE 874
Query: 207 ADSSDKEMKHGQKSPTGK 224
+DS ++ Q P+GK
Sbjct: 875 SDSEEEAETLAQVKPSGK 892
>gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1531
Score = 70.5 bits (171), Expect = 2e-11
Identities = 202/1076 (18%), Positives = 373/1076 (34%), Gaps = 107/1076 (9%)
Query: 541 DSLIPSTSSMTHVSDTEHKESETA-------VETSTPKIKTGSSSLEGQFPNE----GIA 589
++ + + S T + TE E+ TA ST +T ++S G P G
Sbjct: 243 ETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSE 302
Query: 590 IDMELQSDPEEQLSENACISETSFSSESPEGACTSLPSPGGETQSTSEESCTPASL---E 646
M PE A T+ + E S T ST+ T AS+ E
Sbjct: 303 TTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSE 362
Query: 647 TTFCSEVSS---TENTDKYNQRNSTDENFHASLMSEISPISTSPEISEASLMSNLPLTSE 703
T+ S S T +T+ ++ E A+ +S +T+ I+++ + SE
Sbjct: 363 TSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSE 422
Query: 704 ASPVSN--LPLTSETSPMSDLPLTSETSSVSSMLLT--SETTFVSSL--------PLPSE 751
+ VS T+ ++ S++ + S + S ++ T SETT V++ SE
Sbjct: 423 MTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSE 482
Query: 752 TSPISNSSINERMAHQQRKSPSVSEEPLSPQKDESSATAKPLGENLTSQQKNLSNT---- 807
T+ SN+ + + + S + E++A + E T + NT
Sbjct: 483 TTTASNTGLETTTVFTIGSDTTTA----STEGSETTAVSATGSEMTTVSTEGSENTTVST 538
Query: 808 --PEPIIMSSSSIAPEAFPSEDLHNKTLSQQTCKSHVDTEKPYPASIPELASTEMIKV-- 863
E +S++ + +E T+S ++ D+ + + A +E V
Sbjct: 539 TGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVST 598
Query: 864 ---KNHSVLQRTEKKVLPSPLELSVFSEGTDNKGNELPSAKLQDKQYISSVDKAPFSEGS 920
+N + + S + T + S + + +S+ D +
Sbjct: 599 ADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVST 658
Query: 921 RNKTHKQGSTQSRLETSHTSKSSEPSKSPDGIRNESRDSEISKRKTAEQHSFGICKEKRA 980
ST+ T+ ++ SE + S +G + + I+ +T + + G +
Sbjct: 659 TGSERTITSTEGSETTTVSATGSETTVSTEG--SGTTTVSITGSETTKVSTTGSETTTTS 716
Query: 981 RIEDDQSTRNISSSSPPEKEQPPREEPRVPPLKIQLSKIGPPFIIKSQ-PVSKPESRAST 1039
+ +T +I+ S E E + S+ S+ + S +T
Sbjct: 717 TEGSEITTASITGS---ETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETT 773
Query: 1040 STSVSGGRNTGARTLADIKARAQQARAQ--------REAAAAAAVAAAASIVSGA----- 1086
S+ G T A T+ + A ++ E A+ A+ + VS A
Sbjct: 774 MASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETI 833
Query: 1087 -MGSPGEGGKTRTLAHIKEQTKAKLFAKHQARAHLFQTSKETRLPPPLSSKEGPPNLEVS 1145
+ G T T E T A A S ET + S+ + E S
Sbjct: 834 PASTAGSETTTTTSTEGSETTTASTEGSETTTAS--TESSETTTATTIGSETTTASTEGS 891
Query: 1146 STPETKMEGSTGVIIVNPNCRSPSNKSAHLRETTTVLQQSLNPSKLPETATDLSVHSSDE 1205
T T EGS + S + + + +T ++ S T S S+
Sbjct: 892 ETTTTSTEGS--------ETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSEL 943
Query: 1206 NIPVSHLSEKI-VSSTSSENSSVPMLFNKNSVPVSVCSTAISGAIKEHPFVSSVDKSSVL 1264
+ SE I VS+ SE ++V + ++ +T S A E VS+ +
Sbjct: 944 TTVSTTGSETITVSAEGSETTTVTTMGSE--------TTTASTAGSETTTVSTAGSETTT 995
Query: 1265 MSVDSANTTISACNISMLKTIQGTDTPCIAIIPKCIESTPI-SATTEGSSISSSMDDKQL 1323
S++ + TT + S T+ T T + E+T + +A +E +++ ++ +
Sbjct: 996 ASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTT 1055
Query: 1324 LISSSSASNLVSTQYTSVPTPSIGNNLPNLSTSSVLIPPMGINNRFPSEKIAIPGSEEQA 1383
+ S + VST + T S +L T++V G + + GSE
Sbjct: 1056 TSTEGSETTTVSTTGSETTTASTA----DLETTTVSTSGSG------TTTASTAGSETTT 1105
Query: 1384 TVSMGTTVRAALSCSDSVAVTDSLVAHPTVAMFTGNMLTINSYDSPPKLSAESLDKNSGP 1443
G+ A + + + T A TG+ +T + ++ +
Sbjct: 1106 VYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATT 1165
Query: 1444 RNRADNSGKPQQPPGGFAPAAINRSIPCKVIVDHSTTLTSSLSLTVSVESSEASLDLQGR 1503
+ A + G A S T T+S + + + +S A +
Sbjct: 1166 SSAAGSEATTTSTEGSETTTASTAG---------SETTTASTAGSETTTASTAGSET--T 1214
Query: 1504 PVRTEASVQPVACPQVSVISRPEPVANEGIDHSSTFIAASAAKQDSKTLPATCTSL 1559
T S AC S S P +E +++ I + + +L T TSL
Sbjct: 1215 TASTSGSETNTACTTGSETSTPSSAGSE--TNTAFIIGSETTIASTASLEPTATSL 1268
Score = 69.3 bits (168), Expect = 4e-11
Identities = 179/924 (19%), Positives = 320/924 (34%), Gaps = 106/924 (11%)
Query: 547 TSSMTHVSDTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMELQSDPEEQLSENA 606
T S T + TE E TAV T+ + T S+ EG I + SD E
Sbjct: 409 TDSETTTTCTEGSEM-TAVSTTVFETTTAST--------EGSEITIASTSDSET------ 453
Query: 607 CISETSFSSESPEGACTSLPSPGGETQS---TSEESCTPAS--LETTFCSEVSSTENTDK 661
T+ S+E E T++ + G ET++ T E+ T ++ LETT + S T
Sbjct: 454 ----TTASTEGSE--TTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTAS 507
Query: 662 YNQRNSTDENFHASLMSEISP-------ISTSPEISEASLMSNLPLTSEASPVSNLPLTS 714
+T + S M+ +S +ST+ + + L T+ ++ S + S
Sbjct: 508 TEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVS 567
Query: 715 ETSPMSDLPLTSETSSVSSMLLTSETTFVSSLPLPSETSPISNSSINERMAHQQRKSPSV 774
T + T + + ++ SETT VS+ + T+ ++S S +
Sbjct: 568 TTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSA-------STTG 620
Query: 775 SEEPLSPQKDESSATAKPLGENLTSQQKNLSNTPEPIIMSSSSIAPEAFPS-EDLHNKTL 833
SE + + TA G T+ +S T M S++ + S E T+
Sbjct: 621 SETTTASTTSSETTTASTEGSETTT----VSTTDSETTMVSTTGSERTITSTEGSETTTV 676
Query: 834 SQQTCKSHVDTEKPYPASIPELASTEMIKVK---NHSVLQRTEKKVLPSPLELSVFSEGT 890
S ++ V TE ++ + +E KV + + TE + + +
Sbjct: 677 SATGSETTVSTEGSGTTTV-SITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTA 735
Query: 891 DNKGNELPSAKLQDKQYISSVDKAPFSEGSRNKTHKQGSTQSRLET-------------S 937
+G+E +A + + S+ + GS T S+++ + + S
Sbjct: 736 STEGSETTTASTEGSETTSAS-----TTGSETTTASTTSSETTMASIMGSETTMASTIGS 790
Query: 938 HTSKSSEPSKSPDGIRNESRDSEISKRKTAEQHSFGICKEKRARIEDDQS-TRNISSSSP 996
T+K S S + E+ ++ I+ +E + + S T +S+
Sbjct: 791 ETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEG 850
Query: 997 PEKEQPPREEPRVPPLKIQLSKIGPPFIIKSQPVS-KPESRASTSTSVSGGRNTGART-- 1053
E E + S+ I S+ + E +T+TS G T A T
Sbjct: 851 SETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEG 910
Query: 1054 -----LADIKARAQQARAQREAAAAAAVAAAASIVSGAMGSP-----GEGGKTRTLAHIK 1103
++ + A + A+ + GS EG +T T+ +
Sbjct: 911 SEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMG 970
Query: 1104 EQTKAKLFAKHQARAHLFQTSKETRLPPPLSSKEGPPNLEVSST-PETKMEGSTGVIIVN 1162
+T A + S+ T +S EG VSST ET +TG
Sbjct: 971 SETTTASTAGSETTTVSTAGSETTT-----ASIEGSETTTVSSTGSETTTVSTTGT---- 1021
Query: 1163 PNCRSPSNKSAHLRETTTVLQQSLNPSKLPETATDLSVHSSDENIPVSHLSEKIVSSTSS 1222
+ S ETTTV + + T ++ + S++ SE ST+
Sbjct: 1022 ----ETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEG-------SETTTVSTTG 1070
Query: 1223 ENSSVPMLFNKNSVPVSVC---STAISGAIKEHPFVSSVDKSSVLMSVDSANTTISACNI 1279
++ + + VS +T S A E V + S + + T +
Sbjct: 1071 SETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTS 1130
Query: 1280 SMLKTIQGTDTPCIAIIPKCIESTPISATTEGSSISSSMDDKQLLISSS-SASNLVSTQY 1338
S T T + + E+T +S ++ SS+ + S+ S + ST
Sbjct: 1131 SETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAG 1190
Query: 1339 TSVPTPSIGNNLPNLSTSSVLIPPMGINNRFPSEKIAIPGSEEQATVSMGTTVRAALSCS 1398
+ T S + ++++ + + GSE S G+ A
Sbjct: 1191 SETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIG 1250
Query: 1399 DSVAVTDSLVAHPTVAMFTGNMLT 1422
+ + PT TG+ T
Sbjct: 1251 SETTIASTASLEPTATSLTGSETT 1274
Score = 62.4 bits (150), Expect = 5e-09
Identities = 201/1062 (18%), Positives = 359/1062 (33%), Gaps = 147/1062 (13%)
Query: 542 SLIPSTSSMTHVSDTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMELQSDPEEQ 601
++ P+ S T + T E+ T + ++ ++ E P+ + + E
Sbjct: 6 TVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEI 65
Query: 602 LSENACISETSFSSESPEGACTSLPSPGGETQSTSEESCTPASLETTFCSEVSSTENTDK 661
+ + SE + S + G T+ + T ST+ T S+ T + VS+ +
Sbjct: 66 TTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETT 125
Query: 662 YNQRNSTDENFHASLMSEISPISTSPEISEASLMSNLPLTSEASPVSNLPLTSETSPMSD 721
N S++ ++ SE + +ST + + ++ T+ ++ S + +
Sbjct: 126 TNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETI 185
Query: 722 LPLT--SETSSVSSMLLTSETTFVSSLPLPSETSPISNSSINERMAHQQRKSPS-VSEEP 778
P T SET++VS+ SETT VS+ SET+ S AH + + S + E
Sbjct: 186 TPSTAGSETTTVSTA--GSETTTVSTTG--SETTTAST-------AHSETTAASTMGSET 234
Query: 779 LSPQKDESSATAKPLGENLTSQQKNLSNTPEPIIMSSSSIAPEAFPSEDLHNKTLSQQTC 838
S T G T+ S T +ED T S
Sbjct: 235 TKVSTAGSETTVSTAGSETTAASTEDSETNTAF-------------TEDSKTTTASTTGF 281
Query: 839 KSHVDTEKPYPASIPELASTEMIKVKNHSVLQRTEKKVLPSPLELS-VFSEGTDNKGNEL 897
++ T S P +AST + S + KV + E++ VF+ G++
Sbjct: 282 ET---TAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRAST 338
Query: 898 PSAKLQDKQYISSVDKAPFSEGSRNKTHKQGSTQSRLETSHTSKSSEPSKSPDGIRNESR 957
++ S GS T +T S T+ T S + S +G +
Sbjct: 339 VGSETTTVSTTGSETTTASIMGSETST--DSTTGSETTTASTEGSETTTASTEGSEATTV 396
Query: 958 DSEISKRKTAEQHSFGICKEKRARIEDDQSTRNISSSSPPEKEQPPREEPRVPPLKIQLS 1017
+ S+ T I D ++T + S +++
Sbjct: 397 STTGSETTTVS-------------ITDSETTTTCTEGS-------------------EMT 424
Query: 1018 KIGPPFIIKSQPVSKPESRASTSTSVSGGRNTGARTLADIKARAQQARAQREAAAAAAVA 1077
+ + + E T S S T A T + + A +
Sbjct: 425 AVSTT--VFETTTASTEGSEITIASTSDSETTTAST--------EGSETTTVTTAGSETK 474
Query: 1078 AAASIVSGAMGSPGEGGKTRTLAHIKEQTKAKLFAKHQARAHLFQTSKETRLPPPLSSKE 1137
A + S + G +T T+ I T + A S+ T + S E
Sbjct: 475 TAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTV-----STE 529
Query: 1138 GPPNLEVSST-PETKMEGSTGVIIVNPNCRSPSNKSAHLRETTTVLQQSLNPSKLPETAT 1196
G N VS+T ET +TG+ ETTT + + + T
Sbjct: 530 GSENTTVSTTGSETTTVSTTGL------------------ETTTTSTEGSEMTTVSTTGA 571
Query: 1197 DLSVHSSDENIPVSHLSEKIVSSTSSENSSVPMLFNKNSVPVSVCSTAISGAIKEHPFVS 1256
+ + S++ + S+ SE ++V ++N T S A E S
Sbjct: 572 ETTTDSTEGS------GTTAASTAGSETTTVSTADSEN--------TTASTADSETTSAS 617
Query: 1257 SVDKSSVLMSVDSANTTISACNISMLKTIQGTDTPCIAIIPKCIESTPISATTEGSSISS 1316
+ + S S+ TT ++ S T+ TD+ E+T +S T +I+S
Sbjct: 618 TTGSETTTASTTSSETTTASTEGSETTTVSTTDS----------ETTMVSTTGSERTITS 667
Query: 1317 SMDDKQLLISSSSASNLVSTQYTSVPTPSI-----------GNNLPNLSTSSVLIPPMGI 1365
+ + +S++ + VST+ + T SI G+ ST I I
Sbjct: 668 TEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASI 727
Query: 1366 NNRFPSEKIAIPGSEEQATVSMGTTVRAALSCSDSVAVTDSLVAHPTVAMFTGNMLTINS 1425
+ + GSE + G+ +A + + + T+A G+ T+ S
Sbjct: 728 TGS-ETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMAS 786
Query: 1426 ---YDSPPKLSAESLDKNSGPRNRADNSGKPQQPPGGFAPAAINRSIPCKVIVDHSTTLT 1482
++ +A S N A + +IP +TT T
Sbjct: 787 TIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTT 846
Query: 1483 SSLSLTVSVESSEASLDLQGRPVRTEASVQPVACPQVSVISRPEPVANEGIDHSSTFIAA 1542
S+ + S+E S + TE+S A ++ S + EG + ++T
Sbjct: 847 STEGSETTTASTEGS---ETTTASTESSETTTA---TTIGSETTTASTEGSETTTTSTEG 900
Query: 1543 S---AAKQDSKTLPATCTSLRELPLVPDKLNEPTAPSHNFAE 1581
S A + + T+ E + +E T S +E
Sbjct: 901 SETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSE 942
Score = 49.3 bits (116), Expect = 4e-05
Identities = 144/771 (18%), Positives = 258/771 (33%), Gaps = 98/771 (12%)
Query: 1039 TSTSVSGGRNTGARTLADIKARAQQARAQREAAAAAAVAAAASIVS------GAMGS--- 1089
T+TS +G NT + A A ++ + A + SI AMGS
Sbjct: 66 TTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETT 125
Query: 1090 ------------PGEGGKTRTLAHIKEQTKAKLFAKHQARAHLFQTSKETRLPPPLSSKE 1137
G +T T++ + +T A + A T E S+
Sbjct: 126 TNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTA-ASTTGSEMTTVFTAGSET 184
Query: 1138 GPPNLEVSSTPETKMEGSTGVIIVNPNCRSPSNKSAHLRETTTVLQQSLNPSKLPETATD 1197
P+ S T GS + + + +AH ETT +K+ ++
Sbjct: 185 ITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAH-SETTAASTMGSETTKVSTAGSE 243
Query: 1198 LSVHSSDENIPVSHLSEKIVSSTSSENSSVPMLFNKNSVPVSVC-----STAISGAIKEH 1252
+V ++ ++ S+E+S F ++S + +TA S E
Sbjct: 244 TTVSTAGSE----------TTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEP 293
Query: 1253 PFVSSVDKSSVLMSVDSANTTISACNISMLKTIQGTDTPCIAIIPKCIESTPISATTEGS 1312
S++ + + S TT + S + T+ + I E+T +S T +
Sbjct: 294 TMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSET 353
Query: 1313 SISSSMDDKQLLISSS-SASNLVSTQYTSVPTPSI-GNNLPNLSTSSVLIPPMGINNRFP 1370
+ +S M + S++ S + ST+ + T S G+ +ST+
Sbjct: 354 TTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTG-----------SE 402
Query: 1371 SEKIAIPGSEEQATVSMGTTVRAALSCSDSVAVTDSLVAHPTVAMFTGNMLTINSYDSPP 1430
+ ++I SE T + G+ + A + V T A G+ +TI S
Sbjct: 403 TTTVSITDSETTTTCTEGSEMTA----------VSTTVFETTTASTEGSEITIASTSDSE 452
Query: 1431 KLSAESLDKNSGPRNRADNSGKPQQPPGGFAPAAINRSIPCKVI--VDHSTT-------- 1480
+A + + A + K G A N + + + TT
Sbjct: 453 TTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSE 512
Query: 1481 -----LTSSLSLTVSVESSE-ASLDLQGRPVRT------EASVQPVACPQVSVISRPEPV 1528
T S TVS E SE ++ G T E + +++ +S
Sbjct: 513 TTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAE 572
Query: 1529 ANEGIDHSSTFIAASAAKQDSKTLPATCTSLRELPLVPDKLNEPTAPSHNFAEQARGPAP 1588
S AAS A ++ T+ +T S D +E T+ S +E A
Sbjct: 573 TTTDSTEGSGTTAASTAGSETTTV-STADSENTTASTAD--SETTSASTTGSETT--TAS 627
Query: 1589 FKSEADTTCSNQYNPSNRICWNDDG---MRSTG-QPLVTHSGSSKQKEYLEQSCPKAIKT 1644
S TT S + + + + D + +TG + +T + S+ + T
Sbjct: 628 TTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVST 687
Query: 1645 EHANYLNVSELHPRNLVTNVALPVKSELHEADKGFRMDTEDFPGPELPPPAAEGA----S 1700
E + VS T V+ + +G + T G E + EG+ +
Sbjct: 688 EGSGTTTVSITGSE--TTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTA 745
Query: 1701 SVQQTQNMKASTSSPMEEAISLATDALKRVPGAGSSGCRLSSVEANNPLVT 1751
S + ++ AST+ S + GS S++ + V+
Sbjct: 746 STEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVS 796
Score = 43.5 bits (101), Expect = 0.002
Identities = 93/473 (19%), Positives = 165/473 (34%), Gaps = 39/473 (8%)
Query: 373 TTGPNNAGAQSSSSCGTSGLPVSAQTALAEQQPKSMKSPASPEPGFCATLCPMVEIPPKD 432
TT + G++++S+ T +A T +E S+ G T+ +
Sbjct: 742 TTTASTEGSETTSASTTGSETTTASTTSSETTMASIM-------GSETTMASTIGSETTK 794
Query: 433 IMAELESEDILIPEESVIQEEIAEEVETSICECQDENHKTIPEFSEEAESLTNSHEEPQ- 491
+ + E S + IA + +TIP + +E+ T + E
Sbjct: 795 VSTASSKMTTVFTENS--ETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSE 852
Query: 492 -IAPPEDNLESCVMMNDVLETLPHIEVKIEGKSESPQEEMTVVIDQLEVCDSLIPSTSSM 550
+ E+ + ET + E + S + T + S
Sbjct: 853 TTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTS----------TEGSE 902
Query: 551 THVSDTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMEL---QSDPEEQLSENAC 607
T + TE E T ST +T ++S EG EL + E ++ +A
Sbjct: 903 TTTASTEGSEITTV---STTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAE 959
Query: 608 ISETSFSSESPEGACTSLPSPGGE---TQSTSEESCTPASLETTFCSEVSSTENTDKYNQ 664
SET+ + + G+ T+ S G T ST+ T AS+E + + VSST +
Sbjct: 960 GSETT--TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVS 1017
Query: 665 RNSTDENFHASLMSEISPISTSPEISEASLMSNLPLTSEASPVSNLPLTSETSPMSDLPL 724
T+ ++ SE + ++T+ + A + T+ ++ S S T +
Sbjct: 1018 TTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTAS 1077
Query: 725 TSETSSVSSMLLTSETTFVSSLPLPSETSPISNSSINERMAHQQRKSPSVSEEPLSPQKD 784
T++ + + S TT S+ + T I+ S S SE
Sbjct: 1078 TADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTT-------TASTEGSEATTVSTTS 1130
Query: 785 ESSATAKPLGENLTSQQKNLSNTPEPIIMSSSSIAPEAFPSEDLHNKTLSQQT 837
+ TA G +T+ +S T + S + A SE T +T
Sbjct: 1131 SETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSET 1183
Score = 43.5 bits (101), Expect = 0.002
Identities = 71/336 (21%), Positives = 132/336 (39%), Gaps = 19/336 (5%)
Query: 459 ETSICECQDENHKTIPEFSEEAESLTNSHEEPQIAPPEDNLESCVMMNDVLETLPHIEVK 518
ET+I + T+ E ++ + E E + E+ + ET
Sbjct: 1022 ETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGS-ETTTVSTTGSETTTASTAD 1080
Query: 519 IEGKSESPQEEMTVVIDQLEVCDSLIPSTSSMTHVSDTEHKESETAVETSTPKIKTGSSS 578
+E + S T + + T S T + TE E+ T TS+ ++
Sbjct: 1081 LETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTG 1140
Query: 579 LEGQFPNEGIAIDMELQSDPEEQLSENACISETSFSSESPEGACTSLPSPGGETQSTSEE 638
E ++ + + E + +A SE + + S EG+ T+ S G +T+
Sbjct: 1141 SEMTTVFTTVSETTTVSTIGSEATTSSAAGSEAT--TTSTEGSETTTASTAGSETTTA-- 1196
Query: 639 SCTPASLETTFCSEVSSTENTDKYNQRNSTDENFHASLMSEIS-PISTSPEISEASLMSN 697
+ A ETT S S T + ++ N + SE S P S E + A ++ +
Sbjct: 1197 --STAGSETTTASTAGSETTTAS---TSGSETNTACTTGSETSTPSSAGSETNTAFIIGS 1251
Query: 698 ---LPLTSEASPVSNLPLTSETSPMSDLPLTSETSSVSSMLLTSETTFVSSLPLPSETSP 754
+ T+ P + SET+ +S +T+ ++ +S + S TTFV + P
Sbjct: 1252 ETTIASTASLEPTATSLTGSETTTVS---ITASGATAASTTV-SSTTFVLTKATDVSIQP 1307
Query: 755 ISNSSINERMAHQQRKSPSVSEEPLSPQKDESSATA 790
I+N+ ++ R + S S ++P D +++ A
Sbjct: 1308 ITNTPMSGTRTTGTRLTAS-SSVTMAPGMDFTASAA 1342
Score = 40.8 bits (94), Expect = 0.015
Identities = 71/320 (22%), Positives = 121/320 (37%), Gaps = 36/320 (11%)
Query: 1269 SANTTISACNISMLKTIQGTDTPCIAIIPKCIESTPISATTEGSSISS-SMDDKQLLISS 1327
S+ TT++ S T T + I+ K E+T +A+T GS ++ S Q I S
Sbjct: 2 SSETTVAPAAGSNTTTASTTGSETTTILIKASETT--TASTAGSETTTPSPTGSQTTIVS 59
Query: 1328 SSASNLVST-----QYTSVPTPSIGNNLPNLSTSSVLIPPMGINNRFPSEKIAIPGSEEQ 1382
S S + +T + T+V + G +++ S + G + ++I G+E
Sbjct: 60 ISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSE----TTTVSITGTETT 115
Query: 1383 ATVSMGTTVRAALSCSDSVAVTDSLVAHPTVAMFTGNMLTINSYDSPPKLSAESLDKNSG 1442
+MG+ + S VT + + T G+ T +Y + + +A
Sbjct: 116 MVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSE-TTTAYTADSETTA-------- 166
Query: 1443 PRNRADNSGKPQQPPGGFAPAAINRSIPCKVIVDHSTTLTS--SLSLTVSVESSEASLDL 1500
A +G A + +I +TT+++ S + TVS SE +
Sbjct: 167 ----ASTTGSEMTT----VFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTAS 218
Query: 1501 QGRPVRTEASVQPVACPQVSVISRPEPVANEGIDHSSTFIAAS----AAKQDSKTLPATC 1556
T AS +VS V+ G + ++ S A +DSKT A+
Sbjct: 219 TAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTAST 278
Query: 1557 TSLRELPLVPDKLNEPTAPS 1576
T E +EPT S
Sbjct: 279 TGF-ETTAASTTGSEPTMAS 297
>gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo
sapiens]
Length = 1521
Score = 70.5 bits (171), Expect = 2e-11
Identities = 177/921 (19%), Positives = 328/921 (35%), Gaps = 110/921 (11%)
Query: 547 TSSMTHVSDTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMELQSDPEEQLSENA 606
T S T + TE E TAV T+ + T S+ EG I + SD E
Sbjct: 409 TDSETTTTCTEGSEM-TAVSTTVFETTTAST--------EGSEITIASTSDSET------ 453
Query: 607 CISETSFSSESPEGACTSLPSPGGETQS---TSEESCTPAS--LETTFCSEVSSTENTDK 661
T+ S+E E T++ + G ET++ T E+ T ++ LETT + S T
Sbjct: 454 ----TTASTEGSE--TTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTAS 507
Query: 662 YNQRNSTDENFHASLMSEISP-------ISTSPEISEASLMSNLPLTSEASPVSNLPLTS 714
+T + S M+ +S +ST+ + + L T+ ++ S + S
Sbjct: 508 TEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVS 567
Query: 715 ETSPMSDLPLTSETSSVSSMLLTSETTFVSSLPLPSETSPISNSSINERMAHQQRKSPSV 774
T + T + + ++ SETT VS+ + T+ ++S S +
Sbjct: 568 TTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSA-------STTG 620
Query: 775 SEEPLSPQKDESSATAKPLGENLTSQQKNLSNTPEPIIMSSSSIAPEAFPS-EDLHNKTL 833
SE + + TA G T+ +S T M S++ + S E T+
Sbjct: 621 SETTTASTTSSETTTASTEGSETTT----VSTTDSETTMVSTTGSERTITSTEGSETTTV 676
Query: 834 SQQTCKSHVDTEKPYPASIPELASTEMIKVK---NHSVLQRTEKKVLPSPLELSVFSEGT 890
S ++ V TE ++ + +E KV + + + TE + + +
Sbjct: 677 SATGSETTVSTEGSGTTTV-SITGSETTKVSTTGSETTITSTEGSEITTASITGSETTTA 735
Query: 891 DNKGNELPSAKLQDKQYISSVDKAPFSEGSRNKTHKQGSTQSRLET-------------S 937
+G+E +A + + S+ + GS T S+++ + + S
Sbjct: 736 STEGSETTTASTEGSETTSAS-----TTGSETTTASTTSSETTMASIMGSETTMASTIGS 790
Query: 938 HTSKSSEPSKSPDGIRNESRDSEISKRKTAEQHSFGICKEKRARIEDDQS-TRNISSSSP 996
T+K S S + E+ ++ I+ +E + + S T +S+
Sbjct: 791 ETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEG 850
Query: 997 PEKEQPPREEPRVPPLKIQLSKIGPPFIIKSQPVS-KPESRASTSTSVSGGRNTGART-- 1053
E E + S+ I S+ + E +T+TS G T A T
Sbjct: 851 SETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEG 910
Query: 1054 -----LADIKARAQQARAQREAAAAAAVAAAASIVSGAMGSP-----GEGGKTRTLAHIK 1103
++ + A + A+ + GS EG +T T+ +
Sbjct: 911 SEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMG 970
Query: 1104 EQTKAKLFAKHQARAHLFQTSKETRLPPPLSSKEGPPNLEVSST-PETKMEGSTGVIIVN 1162
+T A + S+ T +S EG VSST ET +TG
Sbjct: 971 SETTTASTAGSETTTVSTAGSETTT-----ASIEGSETTTVSSTGSETTTVSTTGT---- 1021
Query: 1163 PNCRSPSNKSAHLRETTTVLQQSLNPSKLPETATDLSVHSSDENIPVSHLSEKIVSSTSS 1222
+ S ETTTV + + T ++ + S++ + + VS+T S
Sbjct: 1022 ----ETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTT------VSTTGS 1071
Query: 1223 ENSSVPMLFNKNSVPVSVCSTAISGAIKEHPFVSSVDKSSVLMSVDSANTTISACNISML 1282
E ++ + + + ST+ SG S+ + + + + TT ++ S
Sbjct: 1072 ETTTA----STADLETTTVSTSGSGTTT----ASTAGSETTTVYITGSKTTTASTEGSEA 1123
Query: 1283 KTIQGTDTPCIAIIPKCIESTPISAT-TEGSSISSSMDDKQLLISSSSASNLVSTQYTSV 1341
T+ T + E T + T +E +++S+ + ++ S + ST+ +
Sbjct: 1124 TTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSET 1183
Query: 1342 PTPSIGNNLPNLSTSSVLIPPMGINNRFPSEKIAIPGSEEQATVSMGTTVRAALSCSDSV 1401
T S + ++++ + + GSE S G+ A
Sbjct: 1184 TTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSET 1243
Query: 1402 AVTDSLVAHPTVAMFTGNMLT 1422
+ + PT TG+ T
Sbjct: 1244 TIASTASLEPTATSLTGSETT 1264
Score = 68.6 bits (166), Expect = 7e-11
Identities = 204/1076 (18%), Positives = 372/1076 (34%), Gaps = 117/1076 (10%)
Query: 541 DSLIPSTSSMTHVSDTEHKESETA-------VETSTPKIKTGSSSLEGQFPNE----GIA 589
++ + + S T + TE E+ TA ST +T ++S G P G
Sbjct: 243 ETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSE 302
Query: 590 IDMELQSDPEEQLSENACISETSFSSESPEGACTSLPSPGGETQSTSEESCTPASL---E 646
M PE A T+ + E S T ST+ T AS+ E
Sbjct: 303 TTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSE 362
Query: 647 TTFCSEVSS---TENTDKYNQRNSTDENFHASLMSEISPISTSPEISEASLMSNLPLTSE 703
T+ S S T +T+ ++ E A+ +S +T+ I+++ + SE
Sbjct: 363 TSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSE 422
Query: 704 ASPVSN--LPLTSETSPMSDLPLTSETSSVSSMLLT--SETTFVSSL--------PLPSE 751
+ VS T+ ++ S++ + S + S ++ T SETT V++ SE
Sbjct: 423 MTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSE 482
Query: 752 TSPISNSSINERMAHQQRKSPSVSEEPLSPQKDESSATAKPLGENLTSQQKNLSNT---- 807
T+ SN+ + + + S + E++A + E T + NT
Sbjct: 483 TTTASNTGLETTTVFTIGSDTTTA----STEGSETTAVSATGSEMTTVSTEGSENTTVST 538
Query: 808 --PEPIIMSSSSIAPEAFPSEDLHNKTLSQQTCKSHVDTEKPYPASIPELASTEMIKV-- 863
E +S++ + +E T+S ++ D+ + + A +E V
Sbjct: 539 TGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVST 598
Query: 864 ---KNHSVLQRTEKKVLPSPLELSVFSEGTDNKGNELPSAKLQDKQYISSVDKAPFSEGS 920
+N + + S + T + S + + +S+ D +
Sbjct: 599 ADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVST 658
Query: 921 RNKTHKQGSTQSRLETSHTSKSSEPSKSPDGIRNESRDSEISKRKTAEQHSFGICKEKRA 980
ST+ T+ ++ SE + S +G + + I+ +T + + G +
Sbjct: 659 TGSERTITSTEGSETTTVSATGSETTVSTEG--SGTTTVSITGSETTKVSTTGSETTITS 716
Query: 981 RIEDDQSTRNISSSSPPEKEQPPREEPRVPPLKIQLSKIGPPFIIKSQ-PVSKPESRAST 1039
+ +T +I+ S E E + S+ S+ + S +T
Sbjct: 717 TEGSEITTASITGS---ETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETT 773
Query: 1040 STSVSGGRNTGARTLADIKARAQQARAQ--------REAAAAAAVAAAASIVSGA----- 1086
S+ G T A T+ + A ++ E A+ A+ + VS A
Sbjct: 774 MASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETI 833
Query: 1087 -MGSPGEGGKTRTLAHIKEQTKAKLFAKHQARAHLFQTSKETRLPPPLSSKEGPPNLEVS 1145
+ G T T E T A A S ET + S+ + E S
Sbjct: 834 PASTAGSETTTTTSTEGSETTTASTEGSETTTAS--TESSETTTATTIGSETTTASTEGS 891
Query: 1146 STPETKMEGSTGVIIVNPNCRSPSNKSAHLRETTTVLQQSLNPSKLPETATDLSVHSSDE 1205
T T EGS + S + + + +T ++ S T S S+
Sbjct: 892 ETTTTSTEGS--------ETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSEL 943
Query: 1206 NIPVSHLSEKI-VSSTSSENSSVPMLFNKNSVPVSVCSTAISGAIKEHPFVSSVDKSSVL 1264
+ SE I VS+ SE ++V + ++ +T S A E VS+ +
Sbjct: 944 TTVSTTGSETITVSAEGSETTTVTTMGSE--------TTTASTAGSETTTVSTAGSETTT 995
Query: 1265 MSVDSANTTISACNISMLKTIQGTDTPCIAIIPKCIESTPI-SATTEGSSISSSMDDKQL 1323
S++ + TT + S T+ T T + E+T + +A +E +++ ++ +
Sbjct: 996 ASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTT 1055
Query: 1324 LISSSSASNLVSTQYTSVPTPSIGNNLPNLSTSSVLIPPMGINNRFPSEKIAIPGSEEQA 1383
+ S + VST + T S +L T++V G + + GSE
Sbjct: 1056 TSTEGSETTTVSTTGSETTTASTA----DLETTTVSTSGSG------TTTASTAGSETTT 1105
Query: 1384 TVSMGTTVRAALSCSDSVAVTDSLVAHPTVAMFTGNMLTINSYDSPPKLSAESLDKNSGP 1443
G+ A + + + T A TG+ +T + ++ +
Sbjct: 1106 VYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATT 1165
Query: 1444 RNRADNSGKPQQPPGGFAPAAINRSIPCKVIVDHSTTLTSSLSLTVSVESSEASLDLQGR 1503
+ A + G A S T T+S T E++ AS
Sbjct: 1166 SSAAGSEATTTSTEGSETTTASTAG---------SETTTAS---TAGSETTTAS------ 1207
Query: 1504 PVRTEASVQPVACPQVSVISRPEPVANEGIDHSSTFIAASAAKQDSKTLPATCTSL 1559
T S AC S S P +E +++ I + + +L T TSL
Sbjct: 1208 ---TSGSETNTACTTGSETSTPSSAGSE--TNTAFIIGSETTIASTASLEPTATSL 1258
Score = 61.2 bits (147), Expect = 1e-08
Identities = 201/1062 (18%), Positives = 359/1062 (33%), Gaps = 147/1062 (13%)
Query: 542 SLIPSTSSMTHVSDTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMELQSDPEEQ 601
++ P+ S T + T E+ T + ++ ++ E P+ + + E
Sbjct: 6 TVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEI 65
Query: 602 LSENACISETSFSSESPEGACTSLPSPGGETQSTSEESCTPASLETTFCSEVSSTENTDK 661
+ + SE + S + G T+ + T ST+ T S+ T + VS+ +
Sbjct: 66 TTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETT 125
Query: 662 YNQRNSTDENFHASLMSEISPISTSPEISEASLMSNLPLTSEASPVSNLPLTSETSPMSD 721
N S++ ++ SE + +ST + + ++ T+ ++ S + +
Sbjct: 126 TNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETI 185
Query: 722 LPLT--SETSSVSSMLLTSETTFVSSLPLPSETSPISNSSINERMAHQQRKSPS-VSEEP 778
P T SET++VS+ SETT VS+ SET+ S AH + + S + E
Sbjct: 186 TPSTAGSETTTVSTA--GSETTTVSTTG--SETTTAST-------AHSETTAASTMGSET 234
Query: 779 LSPQKDESSATAKPLGENLTSQQKNLSNTPEPIIMSSSSIAPEAFPSEDLHNKTLSQQTC 838
S T G T+ S T +ED T S
Sbjct: 235 TKVSTAGSETTVSTAGSETTAASTEDSETNTAF-------------TEDSKTTTASTTGF 281
Query: 839 KSHVDTEKPYPASIPELASTEMIKVKNHSVLQRTEKKVLPSPLELS-VFSEGTDNKGNEL 897
++ T S P +AST + S + KV + E++ VF+ G++
Sbjct: 282 ET---TAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRAST 338
Query: 898 PSAKLQDKQYISSVDKAPFSEGSRNKTHKQGSTQSRLETSHTSKSSEPSKSPDGIRNESR 957
++ S GS T +T S T+ T S + S +G +
Sbjct: 339 VGSETTTVSTTGSETTTASIMGSETST--DSTTGSETTTASTEGSETTTASTEGSEATTV 396
Query: 958 DSEISKRKTAEQHSFGICKEKRARIEDDQSTRNISSSSPPEKEQPPREEPRVPPLKIQLS 1017
+ S+ T I D ++T + S +++
Sbjct: 397 STTGSETTTVS-------------ITDSETTTTCTEGS-------------------EMT 424
Query: 1018 KIGPPFIIKSQPVSKPESRASTSTSVSGGRNTGARTLADIKARAQQARAQREAAAAAAVA 1077
+ + + E T S S T A T + + A +
Sbjct: 425 AVSTT--VFETTTASTEGSEITIASTSDSETTTAST--------EGSETTTVTTAGSETK 474
Query: 1078 AAASIVSGAMGSPGEGGKTRTLAHIKEQTKAKLFAKHQARAHLFQTSKETRLPPPLSSKE 1137
A + S + G +T T+ I T + A S+ T + S E
Sbjct: 475 TAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTV-----STE 529
Query: 1138 GPPNLEVSST-PETKMEGSTGVIIVNPNCRSPSNKSAHLRETTTVLQQSLNPSKLPETAT 1196
G N VS+T ET +TG+ ETTT + + + T
Sbjct: 530 GSENTTVSTTGSETTTVSTTGL------------------ETTTTSTEGSEMTTVSTTGA 571
Query: 1197 DLSVHSSDENIPVSHLSEKIVSSTSSENSSVPMLFNKNSVPVSVCSTAISGAIKEHPFVS 1256
+ + S++ + S+ SE ++V ++N T S A E S
Sbjct: 572 ETTTDSTEGS------GTTAASTAGSETTTVSTADSEN--------TTASTADSETTSAS 617
Query: 1257 SVDKSSVLMSVDSANTTISACNISMLKTIQGTDTPCIAIIPKCIESTPISATTEGSSISS 1316
+ + S S+ TT ++ S T+ TD+ E+T +S T +I+S
Sbjct: 618 TTGSETTTASTTSSETTTASTEGSETTTVSTTDS----------ETTMVSTTGSERTITS 667
Query: 1317 SMDDKQLLISSSSASNLVSTQYTSVPTPSI-----------GNNLPNLSTSSVLIPPMGI 1365
+ + +S++ + VST+ + T SI G+ ST I I
Sbjct: 668 TEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTITSTEGSEITTASI 727
Query: 1366 NNRFPSEKIAIPGSEEQATVSMGTTVRAALSCSDSVAVTDSLVAHPTVAMFTGNMLTINS 1425
+ + GSE + G+ +A + + + T+A G+ T+ S
Sbjct: 728 TGS-ETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMAS 786
Query: 1426 ---YDSPPKLSAESLDKNSGPRNRADNSGKPQQPPGGFAPAAINRSIPCKVIVDHSTTLT 1482
++ +A S N A + +IP +TT T
Sbjct: 787 TIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTT 846
Query: 1483 SSLSLTVSVESSEASLDLQGRPVRTEASVQPVACPQVSVISRPEPVANEGIDHSSTFIAA 1542
S+ + S+E S + TE+S A ++ S + EG + ++T
Sbjct: 847 STEGSETTTASTEGS---ETTTASTESSETTTA---TTIGSETTTASTEGSETTTTSTEG 900
Query: 1543 S---AAKQDSKTLPATCTSLRELPLVPDKLNEPTAPSHNFAE 1581
S A + + T+ E + +E T S +E
Sbjct: 901 SETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSE 942
Score = 48.9 bits (115), Expect = 6e-05
Identities = 144/771 (18%), Positives = 258/771 (33%), Gaps = 98/771 (12%)
Query: 1039 TSTSVSGGRNTGARTLADIKARAQQARAQREAAAAAAVAAAASIVS------GAMGS--- 1089
T+TS +G NT + A A ++ + A + SI AMGS
Sbjct: 66 TTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETT 125
Query: 1090 ------------PGEGGKTRTLAHIKEQTKAKLFAKHQARAHLFQTSKETRLPPPLSSKE 1137
G +T T++ + +T A + A T E S+
Sbjct: 126 TNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTA-ASTTGSEMTTVFTAGSET 184
Query: 1138 GPPNLEVSSTPETKMEGSTGVIIVNPNCRSPSNKSAHLRETTTVLQQSLNPSKLPETATD 1197
P+ S T GS + + + +AH ETT +K+ ++
Sbjct: 185 ITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAH-SETTAASTMGSETTKVSTAGSE 243
Query: 1198 LSVHSSDENIPVSHLSEKIVSSTSSENSSVPMLFNKNSVPVSVC-----STAISGAIKEH 1252
+V ++ ++ S+E+S F ++S + +TA S E
Sbjct: 244 TTVSTAGSE----------TTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEP 293
Query: 1253 PFVSSVDKSSVLMSVDSANTTISACNISMLKTIQGTDTPCIAIIPKCIESTPISATTEGS 1312
S++ + + S TT + S + T+ + I E+T +S T +
Sbjct: 294 TMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSET 353
Query: 1313 SISSSMDDKQLLISSS-SASNLVSTQYTSVPTPSI-GNNLPNLSTSSVLIPPMGINNRFP 1370
+ +S M + S++ S + ST+ + T S G+ +ST+
Sbjct: 354 TTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTG-----------SE 402
Query: 1371 SEKIAIPGSEEQATVSMGTTVRAALSCSDSVAVTDSLVAHPTVAMFTGNMLTINSYDSPP 1430
+ ++I SE T + G+ + A + V T A G+ +TI S
Sbjct: 403 TTTVSITDSETTTTCTEGSEMTA----------VSTTVFETTTASTEGSEITIASTSDSE 452
Query: 1431 KLSAESLDKNSGPRNRADNSGKPQQPPGGFAPAAINRSIPCKVI--VDHSTT-------- 1480
+A + + A + K G A N + + + TT
Sbjct: 453 TTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSE 512
Query: 1481 -----LTSSLSLTVSVESSE-ASLDLQGRPVRT------EASVQPVACPQVSVISRPEPV 1528
T S TVS E SE ++ G T E + +++ +S
Sbjct: 513 TTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAE 572
Query: 1529 ANEGIDHSSTFIAASAAKQDSKTLPATCTSLRELPLVPDKLNEPTAPSHNFAEQARGPAP 1588
S AAS A ++ T+ +T S D +E T+ S +E A
Sbjct: 573 TTTDSTEGSGTTAASTAGSETTTV-STADSENTTASTAD--SETTSASTTGSETT--TAS 627
Query: 1589 FKSEADTTCSNQYNPSNRICWNDDG---MRSTG-QPLVTHSGSSKQKEYLEQSCPKAIKT 1644
S TT S + + + + D + +TG + +T + S+ + T
Sbjct: 628 TTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVST 687
Query: 1645 EHANYLNVSELHPRNLVTNVALPVKSELHEADKGFRMDTEDFPGPELPPPAAEGA----S 1700
E + VS T V+ + +G + T G E + EG+ +
Sbjct: 688 EGSGTTTVSITGSE--TTKVSTTGSETTITSTEGSEITTASITGSETTTASTEGSETTTA 745
Query: 1701 SVQQTQNMKASTSSPMEEAISLATDALKRVPGAGSSGCRLSSVEANNPLVT 1751
S + ++ AST+ S + GS S++ + V+
Sbjct: 746 STEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVS 796
Score = 43.5 bits (101), Expect = 0.002
Identities = 93/473 (19%), Positives = 165/473 (34%), Gaps = 39/473 (8%)
Query: 373 TTGPNNAGAQSSSSCGTSGLPVSAQTALAEQQPKSMKSPASPEPGFCATLCPMVEIPPKD 432
TT + G++++S+ T +A T +E S+ G T+ +
Sbjct: 742 TTTASTEGSETTSASTTGSETTTASTTSSETTMASIM-------GSETTMASTIGSETTK 794
Query: 433 IMAELESEDILIPEESVIQEEIAEEVETSICECQDENHKTIPEFSEEAESLTNSHEEPQ- 491
+ + E S + IA + +TIP + +E+ T + E
Sbjct: 795 VSTASSKMTTVFTENS--ETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSE 852
Query: 492 -IAPPEDNLESCVMMNDVLETLPHIEVKIEGKSESPQEEMTVVIDQLEVCDSLIPSTSSM 550
+ E+ + ET + E + S + T + S
Sbjct: 853 TTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTS----------TEGSE 902
Query: 551 THVSDTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMEL---QSDPEEQLSENAC 607
T + TE E T ST +T ++S EG EL + E ++ +A
Sbjct: 903 TTTASTEGSEITTV---STTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAE 959
Query: 608 ISETSFSSESPEGACTSLPSPGGE---TQSTSEESCTPASLETTFCSEVSSTENTDKYNQ 664
SET+ + + G+ T+ S G T ST+ T AS+E + + VSST +
Sbjct: 960 GSETT--TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVS 1017
Query: 665 RNSTDENFHASLMSEISPISTSPEISEASLMSNLPLTSEASPVSNLPLTSETSPMSDLPL 724
T+ ++ SE + ++T+ + A + T+ ++ S S T +
Sbjct: 1018 TTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTAS 1077
Query: 725 TSETSSVSSMLLTSETTFVSSLPLPSETSPISNSSINERMAHQQRKSPSVSEEPLSPQKD 784
T++ + + S TT S+ + T I+ S S SE
Sbjct: 1078 TADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTT-------TASTEGSEATTVSTTS 1130
Query: 785 ESSATAKPLGENLTSQQKNLSNTPEPIIMSSSSIAPEAFPSEDLHNKTLSQQT 837
+ TA G +T+ +S T + S + A SE T +T
Sbjct: 1131 SETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSET 1183
Score = 40.8 bits (94), Expect = 0.015
Identities = 71/320 (22%), Positives = 121/320 (37%), Gaps = 36/320 (11%)
Query: 1269 SANTTISACNISMLKTIQGTDTPCIAIIPKCIESTPISATTEGSSISS-SMDDKQLLISS 1327
S+ TT++ S T T + I+ K E+T +A+T GS ++ S Q I S
Sbjct: 2 SSETTVAPAAGSNTTTASTTGSETTTILIKASETT--TASTAGSETTTPSPTGSQTTIVS 59
Query: 1328 SSASNLVST-----QYTSVPTPSIGNNLPNLSTSSVLIPPMGINNRFPSEKIAIPGSEEQ 1382
S S + +T + T+V + G +++ S + G + ++I G+E
Sbjct: 60 ISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSE----TTTVSITGTETT 115
Query: 1383 ATVSMGTTVRAALSCSDSVAVTDSLVAHPTVAMFTGNMLTINSYDSPPKLSAESLDKNSG 1442
+MG+ + S VT + + T G+ T +Y + + +A
Sbjct: 116 MVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSE-TTTAYTADSETTA-------- 166
Query: 1443 PRNRADNSGKPQQPPGGFAPAAINRSIPCKVIVDHSTTLTS--SLSLTVSVESSEASLDL 1500
A +G A + +I +TT+++ S + TVS SE +
Sbjct: 167 ----ASTTGSEMTT----VFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTAS 218
Query: 1501 QGRPVRTEASVQPVACPQVSVISRPEPVANEGIDHSSTFIAAS----AAKQDSKTLPATC 1556
T AS +VS V+ G + ++ S A +DSKT A+
Sbjct: 219 TAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTAST 278
Query: 1557 TSLRELPLVPDKLNEPTAPS 1576
T E +EPT S
Sbjct: 279 TGF-ETTAASTTGSEPTMAS 297
Score = 40.4 bits (93), Expect = 0.020
Identities = 75/341 (21%), Positives = 131/341 (38%), Gaps = 39/341 (11%)
Query: 459 ETSICECQDENHKTIPEFSEEAESLTNSHEEPQIAPPEDNLESCVMMNDVLETLPHIEVK 518
ET+I + T+ E ++ + E E + E+ + ET
Sbjct: 1022 ETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGS-ETTTVSTTGSETTTASTAD 1080
Query: 519 IEGKSESPQEEMTVVIDQLEVCDSLIPSTSSMTHVSDTEHKESETAVETSTPKIKTGSSS 578
+E + S T + + T S T + TE E+ T TS+ +T ++S
Sbjct: 1081 LETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSS---ETTTAS 1137
Query: 579 LEGQFPNEGIAIDMELQSDPEEQLSENACISETSFSSESPEGACTSLPSPGGETQSTSEE 638
G E + +SET+ S A TS + G E +TS E
Sbjct: 1138 TTGS-----------------EMTTVFTTVSETTTVSTIGSEATTS-SAAGSEATTTSTE 1179
Query: 639 -----SCTPASLETTFCSEVSSTENTDKYNQRNSTDENFHASLMSEIS-PISTSPEISEA 692
+ + A ETT S S T + ++ N + SE S P S E + A
Sbjct: 1180 GSETTTASTAGSETTTASTAGSETTTAS---TSGSETNTACTTGSETSTPSSAGSETNTA 1236
Query: 693 SLMSN---LPLTSEASPVSNLPLTSETSPMSDLPLTSETSSVSSMLLTSETTFVSSLPLP 749
++ + + T+ P + SET+ +S +T+ ++ +S + S TTFV +
Sbjct: 1237 FIIGSETTIASTASLEPTATSLTGSETTTVS---ITASGATAASTTV-SSTTFVLTKATD 1292
Query: 750 SETSPISNSSINERMAHQQRKSPSVSEEPLSPQKDESSATA 790
PI+N+ ++ R + S S ++P D +++ A
Sbjct: 1293 VSIQPITNTPMSGTRTTGTRLTAS-SSVTMAPGMDFTASAA 1332
>gi|239740674 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1531
Score = 70.5 bits (171), Expect = 2e-11
Identities = 202/1076 (18%), Positives = 373/1076 (34%), Gaps = 107/1076 (9%)
Query: 541 DSLIPSTSSMTHVSDTEHKESETA-------VETSTPKIKTGSSSLEGQFPNE----GIA 589
++ + + S T + TE E+ TA ST +T ++S G P G
Sbjct: 243 ETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSE 302
Query: 590 IDMELQSDPEEQLSENACISETSFSSESPEGACTSLPSPGGETQSTSEESCTPASL---E 646
M PE A T+ + E S T ST+ T AS+ E
Sbjct: 303 TTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSE 362
Query: 647 TTFCSEVSS---TENTDKYNQRNSTDENFHASLMSEISPISTSPEISEASLMSNLPLTSE 703
T+ S S T +T+ ++ E A+ +S +T+ I+++ + SE
Sbjct: 363 TSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSE 422
Query: 704 ASPVSN--LPLTSETSPMSDLPLTSETSSVSSMLLT--SETTFVSSL--------PLPSE 751
+ VS T+ ++ S++ + S + S ++ T SETT V++ SE
Sbjct: 423 MTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSE 482
Query: 752 TSPISNSSINERMAHQQRKSPSVSEEPLSPQKDESSATAKPLGENLTSQQKNLSNT---- 807
T+ SN+ + + + S + E++A + E T + NT
Sbjct: 483 TTTASNTGLETTTVFTIGSDTTTA----STEGSETTAVSATGSEMTTVSTEGSENTTVST 538
Query: 808 --PEPIIMSSSSIAPEAFPSEDLHNKTLSQQTCKSHVDTEKPYPASIPELASTEMIKV-- 863
E +S++ + +E T+S ++ D+ + + A +E V
Sbjct: 539 TGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVST 598
Query: 864 ---KNHSVLQRTEKKVLPSPLELSVFSEGTDNKGNELPSAKLQDKQYISSVDKAPFSEGS 920
+N + + S + T + S + + +S+ D +
Sbjct: 599 ADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVST 658
Query: 921 RNKTHKQGSTQSRLETSHTSKSSEPSKSPDGIRNESRDSEISKRKTAEQHSFGICKEKRA 980
ST+ T+ ++ SE + S +G + + I+ +T + + G +
Sbjct: 659 TGSERTITSTEGSETTTVSATGSETTVSTEG--SGTTTVSITGSETTKVSTTGSETTTTS 716
Query: 981 RIEDDQSTRNISSSSPPEKEQPPREEPRVPPLKIQLSKIGPPFIIKSQ-PVSKPESRAST 1039
+ +T +I+ S E E + S+ S+ + S +T
Sbjct: 717 TEGSEITTASITGS---ETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETT 773
Query: 1040 STSVSGGRNTGARTLADIKARAQQARAQ--------REAAAAAAVAAAASIVSGA----- 1086
S+ G T A T+ + A ++ E A+ A+ + VS A
Sbjct: 774 MASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETI 833
Query: 1087 -MGSPGEGGKTRTLAHIKEQTKAKLFAKHQARAHLFQTSKETRLPPPLSSKEGPPNLEVS 1145
+ G T T E T A A S ET + S+ + E S
Sbjct: 834 PASTAGSETTTTTSTEGSETTTASTEGSETTTAS--TESSETTTATTIGSETTTASTEGS 891
Query: 1146 STPETKMEGSTGVIIVNPNCRSPSNKSAHLRETTTVLQQSLNPSKLPETATDLSVHSSDE 1205
T T EGS + S + + + +T ++ S T S S+
Sbjct: 892 ETTTTSTEGS--------ETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSEL 943
Query: 1206 NIPVSHLSEKI-VSSTSSENSSVPMLFNKNSVPVSVCSTAISGAIKEHPFVSSVDKSSVL 1264
+ SE I VS+ SE ++V + ++ +T S A E VS+ +
Sbjct: 944 TTVSTTGSETITVSAEGSETTTVTTMGSE--------TTTASTAGSETTTVSTAGSETTT 995
Query: 1265 MSVDSANTTISACNISMLKTIQGTDTPCIAIIPKCIESTPI-SATTEGSSISSSMDDKQL 1323
S++ + TT + S T+ T T + E+T + +A +E +++ ++ +
Sbjct: 996 ASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTT 1055
Query: 1324 LISSSSASNLVSTQYTSVPTPSIGNNLPNLSTSSVLIPPMGINNRFPSEKIAIPGSEEQA 1383
+ S + VST + T S +L T++V G + + GSE
Sbjct: 1056 TSTEGSETTTVSTTGSETTTASTA----DLETTTVSTSGSG------TTTASTAGSETTT 1105
Query: 1384 TVSMGTTVRAALSCSDSVAVTDSLVAHPTVAMFTGNMLTINSYDSPPKLSAESLDKNSGP 1443
G+ A + + + T A TG+ +T + ++ +
Sbjct: 1106 VYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATT 1165
Query: 1444 RNRADNSGKPQQPPGGFAPAAINRSIPCKVIVDHSTTLTSSLSLTVSVESSEASLDLQGR 1503
+ A + G A S T T+S + + + +S A +
Sbjct: 1166 SSAAGSEATTTSTEGSETTTASTAG---------SETTTASTAGSETTTASTAGSET--T 1214
Query: 1504 PVRTEASVQPVACPQVSVISRPEPVANEGIDHSSTFIAASAAKQDSKTLPATCTSL 1559
T S AC S S P +E +++ I + + +L T TSL
Sbjct: 1215 TASTSGSETNTACTTGSETSTPSSAGSE--TNTAFIIGSETTIASTASLEPTATSL 1268
Score = 69.3 bits (168), Expect = 4e-11
Identities = 179/924 (19%), Positives = 320/924 (34%), Gaps = 106/924 (11%)
Query: 547 TSSMTHVSDTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMELQSDPEEQLSENA 606
T S T + TE E TAV T+ + T S+ EG I + SD E
Sbjct: 409 TDSETTTTCTEGSEM-TAVSTTVFETTTAST--------EGSEITIASTSDSET------ 453
Query: 607 CISETSFSSESPEGACTSLPSPGGETQS---TSEESCTPAS--LETTFCSEVSSTENTDK 661
T+ S+E E T++ + G ET++ T E+ T ++ LETT + S T
Sbjct: 454 ----TTASTEGSE--TTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTAS 507
Query: 662 YNQRNSTDENFHASLMSEISP-------ISTSPEISEASLMSNLPLTSEASPVSNLPLTS 714
+T + S M+ +S +ST+ + + L T+ ++ S + S
Sbjct: 508 TEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVS 567
Query: 715 ETSPMSDLPLTSETSSVSSMLLTSETTFVSSLPLPSETSPISNSSINERMAHQQRKSPSV 774
T + T + + ++ SETT VS+ + T+ ++S S +
Sbjct: 568 TTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSA-------STTG 620
Query: 775 SEEPLSPQKDESSATAKPLGENLTSQQKNLSNTPEPIIMSSSSIAPEAFPS-EDLHNKTL 833
SE + + TA G T+ +S T M S++ + S E T+
Sbjct: 621 SETTTASTTSSETTTASTEGSETTT----VSTTDSETTMVSTTGSERTITSTEGSETTTV 676
Query: 834 SQQTCKSHVDTEKPYPASIPELASTEMIKVK---NHSVLQRTEKKVLPSPLELSVFSEGT 890
S ++ V TE ++ + +E KV + + TE + + +
Sbjct: 677 SATGSETTVSTEGSGTTTV-SITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTA 735
Query: 891 DNKGNELPSAKLQDKQYISSVDKAPFSEGSRNKTHKQGSTQSRLET-------------S 937
+G+E +A + + S+ + GS T S+++ + + S
Sbjct: 736 STEGSETTTASTEGSETTSAS-----TTGSETTTASTTSSETTMASIMGSETTMASTIGS 790
Query: 938 HTSKSSEPSKSPDGIRNESRDSEISKRKTAEQHSFGICKEKRARIEDDQS-TRNISSSSP 996
T+K S S + E+ ++ I+ +E + + S T +S+
Sbjct: 791 ETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEG 850
Query: 997 PEKEQPPREEPRVPPLKIQLSKIGPPFIIKSQPVS-KPESRASTSTSVSGGRNTGART-- 1053
E E + S+ I S+ + E +T+TS G T A T
Sbjct: 851 SETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEG 910
Query: 1054 -----LADIKARAQQARAQREAAAAAAVAAAASIVSGAMGSP-----GEGGKTRTLAHIK 1103
++ + A + A+ + GS EG +T T+ +
Sbjct: 911 SEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMG 970
Query: 1104 EQTKAKLFAKHQARAHLFQTSKETRLPPPLSSKEGPPNLEVSST-PETKMEGSTGVIIVN 1162
+T A + S+ T +S EG VSST ET +TG
Sbjct: 971 SETTTASTAGSETTTVSTAGSETTT-----ASIEGSETTTVSSTGSETTTVSTTGT---- 1021
Query: 1163 PNCRSPSNKSAHLRETTTVLQQSLNPSKLPETATDLSVHSSDENIPVSHLSEKIVSSTSS 1222
+ S ETTTV + + T ++ + S++ SE ST+
Sbjct: 1022 ----ETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEG-------SETTTVSTTG 1070
Query: 1223 ENSSVPMLFNKNSVPVSVC---STAISGAIKEHPFVSSVDKSSVLMSVDSANTTISACNI 1279
++ + + VS +T S A E V + S + + T +
Sbjct: 1071 SETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTS 1130
Query: 1280 SMLKTIQGTDTPCIAIIPKCIESTPISATTEGSSISSSMDDKQLLISSS-SASNLVSTQY 1338
S T T + + E+T +S ++ SS+ + S+ S + ST
Sbjct: 1131 SETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAG 1190
Query: 1339 TSVPTPSIGNNLPNLSTSSVLIPPMGINNRFPSEKIAIPGSEEQATVSMGTTVRAALSCS 1398
+ T S + ++++ + + GSE S G+ A
Sbjct: 1191 SETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIG 1250
Query: 1399 DSVAVTDSLVAHPTVAMFTGNMLT 1422
+ + PT TG+ T
Sbjct: 1251 SETTIASTASLEPTATSLTGSETT 1274
Score = 62.4 bits (150), Expect = 5e-09
Identities = 201/1062 (18%), Positives = 359/1062 (33%), Gaps = 147/1062 (13%)
Query: 542 SLIPSTSSMTHVSDTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMELQSDPEEQ 601
++ P+ S T + T E+ T + ++ ++ E P+ + + E
Sbjct: 6 TVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEI 65
Query: 602 LSENACISETSFSSESPEGACTSLPSPGGETQSTSEESCTPASLETTFCSEVSSTENTDK 661
+ + SE + S + G T+ + T ST+ T S+ T + VS+ +
Sbjct: 66 TTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETT 125
Query: 662 YNQRNSTDENFHASLMSEISPISTSPEISEASLMSNLPLTSEASPVSNLPLTSETSPMSD 721
N S++ ++ SE + +ST + + ++ T+ ++ S + +
Sbjct: 126 TNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETI 185
Query: 722 LPLT--SETSSVSSMLLTSETTFVSSLPLPSETSPISNSSINERMAHQQRKSPS-VSEEP 778
P T SET++VS+ SETT VS+ SET+ S AH + + S + E
Sbjct: 186 TPSTAGSETTTVSTA--GSETTTVSTTG--SETTTAST-------AHSETTAASTMGSET 234
Query: 779 LSPQKDESSATAKPLGENLTSQQKNLSNTPEPIIMSSSSIAPEAFPSEDLHNKTLSQQTC 838
S T G T+ S T +ED T S
Sbjct: 235 TKVSTAGSETTVSTAGSETTAASTEDSETNTAF-------------TEDSKTTTASTTGF 281
Query: 839 KSHVDTEKPYPASIPELASTEMIKVKNHSVLQRTEKKVLPSPLELS-VFSEGTDNKGNEL 897
++ T S P +AST + S + KV + E++ VF+ G++
Sbjct: 282 ET---TAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRAST 338
Query: 898 PSAKLQDKQYISSVDKAPFSEGSRNKTHKQGSTQSRLETSHTSKSSEPSKSPDGIRNESR 957
++ S GS T +T S T+ T S + S +G +
Sbjct: 339 VGSETTTVSTTGSETTTASIMGSETST--DSTTGSETTTASTEGSETTTASTEGSEATTV 396
Query: 958 DSEISKRKTAEQHSFGICKEKRARIEDDQSTRNISSSSPPEKEQPPREEPRVPPLKIQLS 1017
+ S+ T I D ++T + S +++
Sbjct: 397 STTGSETTTVS-------------ITDSETTTTCTEGS-------------------EMT 424
Query: 1018 KIGPPFIIKSQPVSKPESRASTSTSVSGGRNTGARTLADIKARAQQARAQREAAAAAAVA 1077
+ + + E T S S T A T + + A +
Sbjct: 425 AVSTT--VFETTTASTEGSEITIASTSDSETTTAST--------EGSETTTVTTAGSETK 474
Query: 1078 AAASIVSGAMGSPGEGGKTRTLAHIKEQTKAKLFAKHQARAHLFQTSKETRLPPPLSSKE 1137
A + S + G +T T+ I T + A S+ T + S E
Sbjct: 475 TAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTV-----STE 529
Query: 1138 GPPNLEVSST-PETKMEGSTGVIIVNPNCRSPSNKSAHLRETTTVLQQSLNPSKLPETAT 1196
G N VS+T ET +TG+ ETTT + + + T
Sbjct: 530 GSENTTVSTTGSETTTVSTTGL------------------ETTTTSTEGSEMTTVSTTGA 571
Query: 1197 DLSVHSSDENIPVSHLSEKIVSSTSSENSSVPMLFNKNSVPVSVCSTAISGAIKEHPFVS 1256
+ + S++ + S+ SE ++V ++N T S A E S
Sbjct: 572 ETTTDSTEGS------GTTAASTAGSETTTVSTADSEN--------TTASTADSETTSAS 617
Query: 1257 SVDKSSVLMSVDSANTTISACNISMLKTIQGTDTPCIAIIPKCIESTPISATTEGSSISS 1316
+ + S S+ TT ++ S T+ TD+ E+T +S T +I+S
Sbjct: 618 TTGSETTTASTTSSETTTASTEGSETTTVSTTDS----------ETTMVSTTGSERTITS 667
Query: 1317 SMDDKQLLISSSSASNLVSTQYTSVPTPSI-----------GNNLPNLSTSSVLIPPMGI 1365
+ + +S++ + VST+ + T SI G+ ST I I
Sbjct: 668 TEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASI 727
Query: 1366 NNRFPSEKIAIPGSEEQATVSMGTTVRAALSCSDSVAVTDSLVAHPTVAMFTGNMLTINS 1425
+ + GSE + G+ +A + + + T+A G+ T+ S
Sbjct: 728 TGS-ETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMAS 786
Query: 1426 ---YDSPPKLSAESLDKNSGPRNRADNSGKPQQPPGGFAPAAINRSIPCKVIVDHSTTLT 1482
++ +A S N A + +IP +TT T
Sbjct: 787 TIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTT 846
Query: 1483 SSLSLTVSVESSEASLDLQGRPVRTEASVQPVACPQVSVISRPEPVANEGIDHSSTFIAA 1542
S+ + S+E S + TE+S A ++ S + EG + ++T
Sbjct: 847 STEGSETTTASTEGS---ETTTASTESSETTTA---TTIGSETTTASTEGSETTTTSTEG 900
Query: 1543 S---AAKQDSKTLPATCTSLRELPLVPDKLNEPTAPSHNFAE 1581
S A + + T+ E + +E T S +E
Sbjct: 901 SETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSE 942
Score = 49.3 bits (116), Expect = 4e-05
Identities = 144/771 (18%), Positives = 258/771 (33%), Gaps = 98/771 (12%)
Query: 1039 TSTSVSGGRNTGARTLADIKARAQQARAQREAAAAAAVAAAASIVS------GAMGS--- 1089
T+TS +G NT + A A ++ + A + SI AMGS
Sbjct: 66 TTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETT 125
Query: 1090 ------------PGEGGKTRTLAHIKEQTKAKLFAKHQARAHLFQTSKETRLPPPLSSKE 1137
G +T T++ + +T A + A T E S+
Sbjct: 126 TNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTA-ASTTGSEMTTVFTAGSET 184
Query: 1138 GPPNLEVSSTPETKMEGSTGVIIVNPNCRSPSNKSAHLRETTTVLQQSLNPSKLPETATD 1197
P+ S T GS + + + +AH ETT +K+ ++
Sbjct: 185 ITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAH-SETTAASTMGSETTKVSTAGSE 243
Query: 1198 LSVHSSDENIPVSHLSEKIVSSTSSENSSVPMLFNKNSVPVSVC-----STAISGAIKEH 1252
+V ++ ++ S+E+S F ++S + +TA S E
Sbjct: 244 TTVSTAGSE----------TTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEP 293
Query: 1253 PFVSSVDKSSVLMSVDSANTTISACNISMLKTIQGTDTPCIAIIPKCIESTPISATTEGS 1312
S++ + + S TT + S + T+ + I E+T +S T +
Sbjct: 294 TMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSET 353
Query: 1313 SISSSMDDKQLLISSS-SASNLVSTQYTSVPTPSI-GNNLPNLSTSSVLIPPMGINNRFP 1370
+ +S M + S++ S + ST+ + T S G+ +ST+
Sbjct: 354 TTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTG-----------SE 402
Query: 1371 SEKIAIPGSEEQATVSMGTTVRAALSCSDSVAVTDSLVAHPTVAMFTGNMLTINSYDSPP 1430
+ ++I SE T + G+ + A + V T A G+ +TI S
Sbjct: 403 TTTVSITDSETTTTCTEGSEMTA----------VSTTVFETTTASTEGSEITIASTSDSE 452
Query: 1431 KLSAESLDKNSGPRNRADNSGKPQQPPGGFAPAAINRSIPCKVI--VDHSTT-------- 1480
+A + + A + K G A N + + + TT
Sbjct: 453 TTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSE 512
Query: 1481 -----LTSSLSLTVSVESSE-ASLDLQGRPVRT------EASVQPVACPQVSVISRPEPV 1528
T S TVS E SE ++ G T E + +++ +S
Sbjct: 513 TTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAE 572
Query: 1529 ANEGIDHSSTFIAASAAKQDSKTLPATCTSLRELPLVPDKLNEPTAPSHNFAEQARGPAP 1588
S AAS A ++ T+ +T S D +E T+ S +E A
Sbjct: 573 TTTDSTEGSGTTAASTAGSETTTV-STADSENTTASTAD--SETTSASTTGSETT--TAS 627
Query: 1589 FKSEADTTCSNQYNPSNRICWNDDG---MRSTG-QPLVTHSGSSKQKEYLEQSCPKAIKT 1644
S TT S + + + + D + +TG + +T + S+ + T
Sbjct: 628 TTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVST 687
Query: 1645 EHANYLNVSELHPRNLVTNVALPVKSELHEADKGFRMDTEDFPGPELPPPAAEGA----S 1700
E + VS T V+ + +G + T G E + EG+ +
Sbjct: 688 EGSGTTTVSITGSE--TTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTA 745
Query: 1701 SVQQTQNMKASTSSPMEEAISLATDALKRVPGAGSSGCRLSSVEANNPLVT 1751
S + ++ AST+ S + GS S++ + V+
Sbjct: 746 STEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVS 796
Score = 43.5 bits (101), Expect = 0.002
Identities = 93/473 (19%), Positives = 165/473 (34%), Gaps = 39/473 (8%)
Query: 373 TTGPNNAGAQSSSSCGTSGLPVSAQTALAEQQPKSMKSPASPEPGFCATLCPMVEIPPKD 432
TT + G++++S+ T +A T +E S+ G T+ +
Sbjct: 742 TTTASTEGSETTSASTTGSETTTASTTSSETTMASIM-------GSETTMASTIGSETTK 794
Query: 433 IMAELESEDILIPEESVIQEEIAEEVETSICECQDENHKTIPEFSEEAESLTNSHEEPQ- 491
+ + E S + IA + +TIP + +E+ T + E
Sbjct: 795 VSTASSKMTTVFTENS--ETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSE 852
Query: 492 -IAPPEDNLESCVMMNDVLETLPHIEVKIEGKSESPQEEMTVVIDQLEVCDSLIPSTSSM 550
+ E+ + ET + E + S + T + S
Sbjct: 853 TTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTS----------TEGSE 902
Query: 551 THVSDTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMEL---QSDPEEQLSENAC 607
T + TE E T ST +T ++S EG EL + E ++ +A
Sbjct: 903 TTTASTEGSEITTV---STTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAE 959
Query: 608 ISETSFSSESPEGACTSLPSPGGE---TQSTSEESCTPASLETTFCSEVSSTENTDKYNQ 664
SET+ + + G+ T+ S G T ST+ T AS+E + + VSST +
Sbjct: 960 GSETT--TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVS 1017
Query: 665 RNSTDENFHASLMSEISPISTSPEISEASLMSNLPLTSEASPVSNLPLTSETSPMSDLPL 724
T+ ++ SE + ++T+ + A + T+ ++ S S T +
Sbjct: 1018 TTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTAS 1077
Query: 725 TSETSSVSSMLLTSETTFVSSLPLPSETSPISNSSINERMAHQQRKSPSVSEEPLSPQKD 784
T++ + + S TT S+ + T I+ S S SE
Sbjct: 1078 TADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTT-------TASTEGSEATTVSTTS 1130
Query: 785 ESSATAKPLGENLTSQQKNLSNTPEPIIMSSSSIAPEAFPSEDLHNKTLSQQT 837
+ TA G +T+ +S T + S + A SE T +T
Sbjct: 1131 SETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSET 1183
Score = 43.5 bits (101), Expect = 0.002
Identities = 71/336 (21%), Positives = 132/336 (39%), Gaps = 19/336 (5%)
Query: 459 ETSICECQDENHKTIPEFSEEAESLTNSHEEPQIAPPEDNLESCVMMNDVLETLPHIEVK 518
ET+I + T+ E ++ + E E + E+ + ET
Sbjct: 1022 ETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGS-ETTTVSTTGSETTTASTAD 1080
Query: 519 IEGKSESPQEEMTVVIDQLEVCDSLIPSTSSMTHVSDTEHKESETAVETSTPKIKTGSSS 578
+E + S T + + T S T + TE E+ T TS+ ++
Sbjct: 1081 LETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTG 1140
Query: 579 LEGQFPNEGIAIDMELQSDPEEQLSENACISETSFSSESPEGACTSLPSPGGETQSTSEE 638
E ++ + + E + +A SE + + S EG+ T+ S G +T+
Sbjct: 1141 SEMTTVFTTVSETTTVSTIGSEATTSSAAGSEAT--TTSTEGSETTTASTAGSETTTA-- 1196
Query: 639 SCTPASLETTFCSEVSSTENTDKYNQRNSTDENFHASLMSEIS-PISTSPEISEASLMSN 697
+ A ETT S S T + ++ N + SE S P S E + A ++ +
Sbjct: 1197 --STAGSETTTASTAGSETTTAS---TSGSETNTACTTGSETSTPSSAGSETNTAFIIGS 1251
Query: 698 ---LPLTSEASPVSNLPLTSETSPMSDLPLTSETSSVSSMLLTSETTFVSSLPLPSETSP 754
+ T+ P + SET+ +S +T+ ++ +S + S TTFV + P
Sbjct: 1252 ETTIASTASLEPTATSLTGSETTTVS---ITASGATAASTTV-SSTTFVLTKATDVSIQP 1307
Query: 755 ISNSSINERMAHQQRKSPSVSEEPLSPQKDESSATA 790
I+N+ ++ R + S S ++P D +++ A
Sbjct: 1308 ITNTPMSGTRTTGTRLTAS-SSVTMAPGMDFTASAA 1342
Score = 40.8 bits (94), Expect = 0.015
Identities = 71/320 (22%), Positives = 121/320 (37%), Gaps = 36/320 (11%)
Query: 1269 SANTTISACNISMLKTIQGTDTPCIAIIPKCIESTPISATTEGSSISS-SMDDKQLLISS 1327
S+ TT++ S T T + I+ K E+T +A+T GS ++ S Q I S
Sbjct: 2 SSETTVAPAAGSNTTTASTTGSETTTILIKASETT--TASTAGSETTTPSPTGSQTTIVS 59
Query: 1328 SSASNLVST-----QYTSVPTPSIGNNLPNLSTSSVLIPPMGINNRFPSEKIAIPGSEEQ 1382
S S + +T + T+V + G +++ S + G + ++I G+E
Sbjct: 60 ISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSE----TTTVSITGTETT 115
Query: 1383 ATVSMGTTVRAALSCSDSVAVTDSLVAHPTVAMFTGNMLTINSYDSPPKLSAESLDKNSG 1442
+MG+ + S VT + + T G+ T +Y + + +A
Sbjct: 116 MVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSE-TTTAYTADSETTA-------- 166
Query: 1443 PRNRADNSGKPQQPPGGFAPAAINRSIPCKVIVDHSTTLTS--SLSLTVSVESSEASLDL 1500
A +G A + +I +TT+++ S + TVS SE +
Sbjct: 167 ----ASTTGSEMTT----VFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTAS 218
Query: 1501 QGRPVRTEASVQPVACPQVSVISRPEPVANEGIDHSSTFIAAS----AAKQDSKTLPATC 1556
T AS +VS V+ G + ++ S A +DSKT A+
Sbjct: 219 TAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTAST 278
Query: 1557 TSLRELPLVPDKLNEPTAPS 1576
T E +EPT S
Sbjct: 279 TGF-ETTAASTTGSEPTMAS 297
>gi|239740645 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1531
Score = 70.5 bits (171), Expect = 2e-11
Identities = 202/1076 (18%), Positives = 373/1076 (34%), Gaps = 107/1076 (9%)
Query: 541 DSLIPSTSSMTHVSDTEHKESETA-------VETSTPKIKTGSSSLEGQFPNE----GIA 589
++ + + S T + TE E+ TA ST +T ++S G P G
Sbjct: 243 ETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSE 302
Query: 590 IDMELQSDPEEQLSENACISETSFSSESPEGACTSLPSPGGETQSTSEESCTPASL---E 646
M PE A T+ + E S T ST+ T AS+ E
Sbjct: 303 TTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSE 362
Query: 647 TTFCSEVSS---TENTDKYNQRNSTDENFHASLMSEISPISTSPEISEASLMSNLPLTSE 703
T+ S S T +T+ ++ E A+ +S +T+ I+++ + SE
Sbjct: 363 TSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSE 422
Query: 704 ASPVSN--LPLTSETSPMSDLPLTSETSSVSSMLLT--SETTFVSSL--------PLPSE 751
+ VS T+ ++ S++ + S + S ++ T SETT V++ SE
Sbjct: 423 MTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSE 482
Query: 752 TSPISNSSINERMAHQQRKSPSVSEEPLSPQKDESSATAKPLGENLTSQQKNLSNT---- 807
T+ SN+ + + + S + E++A + E T + NT
Sbjct: 483 TTTASNTGLETTTVFTIGSDTTTA----STEGSETTAVSATGSEMTTVSTEGSENTTVST 538
Query: 808 --PEPIIMSSSSIAPEAFPSEDLHNKTLSQQTCKSHVDTEKPYPASIPELASTEMIKV-- 863
E +S++ + +E T+S ++ D+ + + A +E V
Sbjct: 539 TGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVST 598
Query: 864 ---KNHSVLQRTEKKVLPSPLELSVFSEGTDNKGNELPSAKLQDKQYISSVDKAPFSEGS 920
+N + + S + T + S + + +S+ D +
Sbjct: 599 ADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVST 658
Query: 921 RNKTHKQGSTQSRLETSHTSKSSEPSKSPDGIRNESRDSEISKRKTAEQHSFGICKEKRA 980
ST+ T+ ++ SE + S +G + + I+ +T + + G +
Sbjct: 659 TGSERTITSTEGSETTTVSATGSETTVSTEG--SGTTTVSITGSETTKVSTTGSETTTTS 716
Query: 981 RIEDDQSTRNISSSSPPEKEQPPREEPRVPPLKIQLSKIGPPFIIKSQ-PVSKPESRAST 1039
+ +T +I+ S E E + S+ S+ + S +T
Sbjct: 717 TEGSEITTASITGS---ETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETT 773
Query: 1040 STSVSGGRNTGARTLADIKARAQQARAQ--------REAAAAAAVAAAASIVSGA----- 1086
S+ G T A T+ + A ++ E A+ A+ + VS A
Sbjct: 774 MASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETI 833
Query: 1087 -MGSPGEGGKTRTLAHIKEQTKAKLFAKHQARAHLFQTSKETRLPPPLSSKEGPPNLEVS 1145
+ G T T E T A A S ET + S+ + E S
Sbjct: 834 PASTAGSETTTTTSTEGSETTTASTEGSETTTAS--TESSETTTATTIGSETTTASTEGS 891
Query: 1146 STPETKMEGSTGVIIVNPNCRSPSNKSAHLRETTTVLQQSLNPSKLPETATDLSVHSSDE 1205
T T EGS + S + + + +T ++ S T S S+
Sbjct: 892 ETTTTSTEGS--------ETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSEL 943
Query: 1206 NIPVSHLSEKI-VSSTSSENSSVPMLFNKNSVPVSVCSTAISGAIKEHPFVSSVDKSSVL 1264
+ SE I VS+ SE ++V + ++ +T S A E VS+ +
Sbjct: 944 TTVSTTGSETITVSAEGSETTTVTTMGSE--------TTTASTAGSETTTVSTAGSETTT 995
Query: 1265 MSVDSANTTISACNISMLKTIQGTDTPCIAIIPKCIESTPI-SATTEGSSISSSMDDKQL 1323
S++ + TT + S T+ T T + E+T + +A +E +++ ++ +
Sbjct: 996 ASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTT 1055
Query: 1324 LISSSSASNLVSTQYTSVPTPSIGNNLPNLSTSSVLIPPMGINNRFPSEKIAIPGSEEQA 1383
+ S + VST + T S +L T++V G + + GSE
Sbjct: 1056 TSTEGSETTTVSTTGSETTTASTA----DLETTTVSTSGSG------TTTASTAGSETTT 1105
Query: 1384 TVSMGTTVRAALSCSDSVAVTDSLVAHPTVAMFTGNMLTINSYDSPPKLSAESLDKNSGP 1443
G+ A + + + T A TG+ +T + ++ +
Sbjct: 1106 VYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATT 1165
Query: 1444 RNRADNSGKPQQPPGGFAPAAINRSIPCKVIVDHSTTLTSSLSLTVSVESSEASLDLQGR 1503
+ A + G A S T T+S + + + +S A +
Sbjct: 1166 SSAAGSEATTTSTEGSETTTASTAG---------SETTTASTAGSETTTASTAGSET--T 1214
Query: 1504 PVRTEASVQPVACPQVSVISRPEPVANEGIDHSSTFIAASAAKQDSKTLPATCTSL 1559
T S AC S S P +E +++ I + + +L T TSL
Sbjct: 1215 TASTSGSETNTACTTGSETSTPSSAGSE--TNTAFIIGSETTIASTASLEPTATSL 1268
Score = 69.3 bits (168), Expect = 4e-11
Identities = 179/924 (19%), Positives = 320/924 (34%), Gaps = 106/924 (11%)
Query: 547 TSSMTHVSDTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMELQSDPEEQLSENA 606
T S T + TE E TAV T+ + T S+ EG I + SD E
Sbjct: 409 TDSETTTTCTEGSEM-TAVSTTVFETTTAST--------EGSEITIASTSDSET------ 453
Query: 607 CISETSFSSESPEGACTSLPSPGGETQS---TSEESCTPAS--LETTFCSEVSSTENTDK 661
T+ S+E E T++ + G ET++ T E+ T ++ LETT + S T
Sbjct: 454 ----TTASTEGSE--TTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTAS 507
Query: 662 YNQRNSTDENFHASLMSEISP-------ISTSPEISEASLMSNLPLTSEASPVSNLPLTS 714
+T + S M+ +S +ST+ + + L T+ ++ S + S
Sbjct: 508 TEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVS 567
Query: 715 ETSPMSDLPLTSETSSVSSMLLTSETTFVSSLPLPSETSPISNSSINERMAHQQRKSPSV 774
T + T + + ++ SETT VS+ + T+ ++S S +
Sbjct: 568 TTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSA-------STTG 620
Query: 775 SEEPLSPQKDESSATAKPLGENLTSQQKNLSNTPEPIIMSSSSIAPEAFPS-EDLHNKTL 833
SE + + TA G T+ +S T M S++ + S E T+
Sbjct: 621 SETTTASTTSSETTTASTEGSETTT----VSTTDSETTMVSTTGSERTITSTEGSETTTV 676
Query: 834 SQQTCKSHVDTEKPYPASIPELASTEMIKVK---NHSVLQRTEKKVLPSPLELSVFSEGT 890
S ++ V TE ++ + +E KV + + TE + + +
Sbjct: 677 SATGSETTVSTEGSGTTTV-SITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTA 735
Query: 891 DNKGNELPSAKLQDKQYISSVDKAPFSEGSRNKTHKQGSTQSRLET-------------S 937
+G+E +A + + S+ + GS T S+++ + + S
Sbjct: 736 STEGSETTTASTEGSETTSAS-----TTGSETTTASTTSSETTMASIMGSETTMASTIGS 790
Query: 938 HTSKSSEPSKSPDGIRNESRDSEISKRKTAEQHSFGICKEKRARIEDDQS-TRNISSSSP 996
T+K S S + E+ ++ I+ +E + + S T +S+
Sbjct: 791 ETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEG 850
Query: 997 PEKEQPPREEPRVPPLKIQLSKIGPPFIIKSQPVS-KPESRASTSTSVSGGRNTGART-- 1053
E E + S+ I S+ + E +T+TS G T A T
Sbjct: 851 SETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEG 910
Query: 1054 -----LADIKARAQQARAQREAAAAAAVAAAASIVSGAMGSP-----GEGGKTRTLAHIK 1103
++ + A + A+ + GS EG +T T+ +
Sbjct: 911 SEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMG 970
Query: 1104 EQTKAKLFAKHQARAHLFQTSKETRLPPPLSSKEGPPNLEVSST-PETKMEGSTGVIIVN 1162
+T A + S+ T +S EG VSST ET +TG
Sbjct: 971 SETTTASTAGSETTTVSTAGSETTT-----ASIEGSETTTVSSTGSETTTVSTTGT---- 1021
Query: 1163 PNCRSPSNKSAHLRETTTVLQQSLNPSKLPETATDLSVHSSDENIPVSHLSEKIVSSTSS 1222
+ S ETTTV + + T ++ + S++ SE ST+
Sbjct: 1022 ----ETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEG-------SETTTVSTTG 1070
Query: 1223 ENSSVPMLFNKNSVPVSVC---STAISGAIKEHPFVSSVDKSSVLMSVDSANTTISACNI 1279
++ + + VS +T S A E V + S + + T +
Sbjct: 1071 SETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTS 1130
Query: 1280 SMLKTIQGTDTPCIAIIPKCIESTPISATTEGSSISSSMDDKQLLISSS-SASNLVSTQY 1338
S T T + + E+T +S ++ SS+ + S+ S + ST
Sbjct: 1131 SETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAG 1190
Query: 1339 TSVPTPSIGNNLPNLSTSSVLIPPMGINNRFPSEKIAIPGSEEQATVSMGTTVRAALSCS 1398
+ T S + ++++ + + GSE S G+ A
Sbjct: 1191 SETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIG 1250
Query: 1399 DSVAVTDSLVAHPTVAMFTGNMLT 1422
+ + PT TG+ T
Sbjct: 1251 SETTIASTASLEPTATSLTGSETT 1274
Score = 62.4 bits (150), Expect = 5e-09
Identities = 201/1062 (18%), Positives = 359/1062 (33%), Gaps = 147/1062 (13%)
Query: 542 SLIPSTSSMTHVSDTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMELQSDPEEQ 601
++ P+ S T + T E+ T + ++ ++ E P+ + + E
Sbjct: 6 TVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEI 65
Query: 602 LSENACISETSFSSESPEGACTSLPSPGGETQSTSEESCTPASLETTFCSEVSSTENTDK 661
+ + SE + S + G T+ + T ST+ T S+ T + VS+ +
Sbjct: 66 TTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETT 125
Query: 662 YNQRNSTDENFHASLMSEISPISTSPEISEASLMSNLPLTSEASPVSNLPLTSETSPMSD 721
N S++ ++ SE + +ST + + ++ T+ ++ S + +
Sbjct: 126 TNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETI 185
Query: 722 LPLT--SETSSVSSMLLTSETTFVSSLPLPSETSPISNSSINERMAHQQRKSPS-VSEEP 778
P T SET++VS+ SETT VS+ SET+ S AH + + S + E
Sbjct: 186 TPSTAGSETTTVSTA--GSETTTVSTTG--SETTTAST-------AHSETTAASTMGSET 234
Query: 779 LSPQKDESSATAKPLGENLTSQQKNLSNTPEPIIMSSSSIAPEAFPSEDLHNKTLSQQTC 838
S T G T+ S T +ED T S
Sbjct: 235 TKVSTAGSETTVSTAGSETTAASTEDSETNTAF-------------TEDSKTTTASTTGF 281
Query: 839 KSHVDTEKPYPASIPELASTEMIKVKNHSVLQRTEKKVLPSPLELS-VFSEGTDNKGNEL 897
++ T S P +AST + S + KV + E++ VF+ G++
Sbjct: 282 ET---TAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRAST 338
Query: 898 PSAKLQDKQYISSVDKAPFSEGSRNKTHKQGSTQSRLETSHTSKSSEPSKSPDGIRNESR 957
++ S GS T +T S T+ T S + S +G +
Sbjct: 339 VGSETTTVSTTGSETTTASIMGSETST--DSTTGSETTTASTEGSETTTASTEGSEATTV 396
Query: 958 DSEISKRKTAEQHSFGICKEKRARIEDDQSTRNISSSSPPEKEQPPREEPRVPPLKIQLS 1017
+ S+ T I D ++T + S +++
Sbjct: 397 STTGSETTTVS-------------ITDSETTTTCTEGS-------------------EMT 424
Query: 1018 KIGPPFIIKSQPVSKPESRASTSTSVSGGRNTGARTLADIKARAQQARAQREAAAAAAVA 1077
+ + + E T S S T A T + + A +
Sbjct: 425 AVSTT--VFETTTASTEGSEITIASTSDSETTTAST--------EGSETTTVTTAGSETK 474
Query: 1078 AAASIVSGAMGSPGEGGKTRTLAHIKEQTKAKLFAKHQARAHLFQTSKETRLPPPLSSKE 1137
A + S + G +T T+ I T + A S+ T + S E
Sbjct: 475 TAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTV-----STE 529
Query: 1138 GPPNLEVSST-PETKMEGSTGVIIVNPNCRSPSNKSAHLRETTTVLQQSLNPSKLPETAT 1196
G N VS+T ET +TG+ ETTT + + + T
Sbjct: 530 GSENTTVSTTGSETTTVSTTGL------------------ETTTTSTEGSEMTTVSTTGA 571
Query: 1197 DLSVHSSDENIPVSHLSEKIVSSTSSENSSVPMLFNKNSVPVSVCSTAISGAIKEHPFVS 1256
+ + S++ + S+ SE ++V ++N T S A E S
Sbjct: 572 ETTTDSTEGS------GTTAASTAGSETTTVSTADSEN--------TTASTADSETTSAS 617
Query: 1257 SVDKSSVLMSVDSANTTISACNISMLKTIQGTDTPCIAIIPKCIESTPISATTEGSSISS 1316
+ + S S+ TT ++ S T+ TD+ E+T +S T +I+S
Sbjct: 618 TTGSETTTASTTSSETTTASTEGSETTTVSTTDS----------ETTMVSTTGSERTITS 667
Query: 1317 SMDDKQLLISSSSASNLVSTQYTSVPTPSI-----------GNNLPNLSTSSVLIPPMGI 1365
+ + +S++ + VST+ + T SI G+ ST I I
Sbjct: 668 TEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASI 727
Query: 1366 NNRFPSEKIAIPGSEEQATVSMGTTVRAALSCSDSVAVTDSLVAHPTVAMFTGNMLTINS 1425
+ + GSE + G+ +A + + + T+A G+ T+ S
Sbjct: 728 TGS-ETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMAS 786
Query: 1426 ---YDSPPKLSAESLDKNSGPRNRADNSGKPQQPPGGFAPAAINRSIPCKVIVDHSTTLT 1482
++ +A S N A + +IP +TT T
Sbjct: 787 TIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTT 846
Query: 1483 SSLSLTVSVESSEASLDLQGRPVRTEASVQPVACPQVSVISRPEPVANEGIDHSSTFIAA 1542
S+ + S+E S + TE+S A ++ S + EG + ++T
Sbjct: 847 STEGSETTTASTEGS---ETTTASTESSETTTA---TTIGSETTTASTEGSETTTTSTEG 900
Query: 1543 S---AAKQDSKTLPATCTSLRELPLVPDKLNEPTAPSHNFAE 1581
S A + + T+ E + +E T S +E
Sbjct: 901 SETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSE 942
Score = 49.3 bits (116), Expect = 4e-05
Identities = 144/771 (18%), Positives = 258/771 (33%), Gaps = 98/771 (12%)
Query: 1039 TSTSVSGGRNTGARTLADIKARAQQARAQREAAAAAAVAAAASIVS------GAMGS--- 1089
T+TS +G NT + A A ++ + A + SI AMGS
Sbjct: 66 TTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETT 125
Query: 1090 ------------PGEGGKTRTLAHIKEQTKAKLFAKHQARAHLFQTSKETRLPPPLSSKE 1137
G +T T++ + +T A + A T E S+
Sbjct: 126 TNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTA-ASTTGSEMTTVFTAGSET 184
Query: 1138 GPPNLEVSSTPETKMEGSTGVIIVNPNCRSPSNKSAHLRETTTVLQQSLNPSKLPETATD 1197
P+ S T GS + + + +AH ETT +K+ ++
Sbjct: 185 ITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAH-SETTAASTMGSETTKVSTAGSE 243
Query: 1198 LSVHSSDENIPVSHLSEKIVSSTSSENSSVPMLFNKNSVPVSVC-----STAISGAIKEH 1252
+V ++ ++ S+E+S F ++S + +TA S E
Sbjct: 244 TTVSTAGSE----------TTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEP 293
Query: 1253 PFVSSVDKSSVLMSVDSANTTISACNISMLKTIQGTDTPCIAIIPKCIESTPISATTEGS 1312
S++ + + S TT + S + T+ + I E+T +S T +
Sbjct: 294 TMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSET 353
Query: 1313 SISSSMDDKQLLISSS-SASNLVSTQYTSVPTPSI-GNNLPNLSTSSVLIPPMGINNRFP 1370
+ +S M + S++ S + ST+ + T S G+ +ST+
Sbjct: 354 TTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTG-----------SE 402
Query: 1371 SEKIAIPGSEEQATVSMGTTVRAALSCSDSVAVTDSLVAHPTVAMFTGNMLTINSYDSPP 1430
+ ++I SE T + G+ + A + V T A G+ +TI S
Sbjct: 403 TTTVSITDSETTTTCTEGSEMTA----------VSTTVFETTTASTEGSEITIASTSDSE 452
Query: 1431 KLSAESLDKNSGPRNRADNSGKPQQPPGGFAPAAINRSIPCKVI--VDHSTT-------- 1480
+A + + A + K G A N + + + TT
Sbjct: 453 TTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSE 512
Query: 1481 -----LTSSLSLTVSVESSE-ASLDLQGRPVRT------EASVQPVACPQVSVISRPEPV 1528
T S TVS E SE ++ G T E + +++ +S
Sbjct: 513 TTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAE 572
Query: 1529 ANEGIDHSSTFIAASAAKQDSKTLPATCTSLRELPLVPDKLNEPTAPSHNFAEQARGPAP 1588
S AAS A ++ T+ +T S D +E T+ S +E A
Sbjct: 573 TTTDSTEGSGTTAASTAGSETTTV-STADSENTTASTAD--SETTSASTTGSETT--TAS 627
Query: 1589 FKSEADTTCSNQYNPSNRICWNDDG---MRSTG-QPLVTHSGSSKQKEYLEQSCPKAIKT 1644
S TT S + + + + D + +TG + +T + S+ + T
Sbjct: 628 TTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVST 687
Query: 1645 EHANYLNVSELHPRNLVTNVALPVKSELHEADKGFRMDTEDFPGPELPPPAAEGA----S 1700
E + VS T V+ + +G + T G E + EG+ +
Sbjct: 688 EGSGTTTVSITGSE--TTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTA 745
Query: 1701 SVQQTQNMKASTSSPMEEAISLATDALKRVPGAGSSGCRLSSVEANNPLVT 1751
S + ++ AST+ S + GS S++ + V+
Sbjct: 746 STEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVS 796
Score = 43.5 bits (101), Expect = 0.002
Identities = 93/473 (19%), Positives = 165/473 (34%), Gaps = 39/473 (8%)
Query: 373 TTGPNNAGAQSSSSCGTSGLPVSAQTALAEQQPKSMKSPASPEPGFCATLCPMVEIPPKD 432
TT + G++++S+ T +A T +E S+ G T+ +
Sbjct: 742 TTTASTEGSETTSASTTGSETTTASTTSSETTMASIM-------GSETTMASTIGSETTK 794
Query: 433 IMAELESEDILIPEESVIQEEIAEEVETSICECQDENHKTIPEFSEEAESLTNSHEEPQ- 491
+ + E S + IA + +TIP + +E+ T + E
Sbjct: 795 VSTASSKMTTVFTENS--ETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSE 852
Query: 492 -IAPPEDNLESCVMMNDVLETLPHIEVKIEGKSESPQEEMTVVIDQLEVCDSLIPSTSSM 550
+ E+ + ET + E + S + T + S
Sbjct: 853 TTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTS----------TEGSE 902
Query: 551 THVSDTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMEL---QSDPEEQLSENAC 607
T + TE E T ST +T ++S EG EL + E ++ +A
Sbjct: 903 TTTASTEGSEITTV---STTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAE 959
Query: 608 ISETSFSSESPEGACTSLPSPGGE---TQSTSEESCTPASLETTFCSEVSSTENTDKYNQ 664
SET+ + + G+ T+ S G T ST+ T AS+E + + VSST +
Sbjct: 960 GSETT--TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVS 1017
Query: 665 RNSTDENFHASLMSEISPISTSPEISEASLMSNLPLTSEASPVSNLPLTSETSPMSDLPL 724
T+ ++ SE + ++T+ + A + T+ ++ S S T +
Sbjct: 1018 TTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTAS 1077
Query: 725 TSETSSVSSMLLTSETTFVSSLPLPSETSPISNSSINERMAHQQRKSPSVSEEPLSPQKD 784
T++ + + S TT S+ + T I+ S S SE
Sbjct: 1078 TADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTT-------TASTEGSEATTVSTTS 1130
Query: 785 ESSATAKPLGENLTSQQKNLSNTPEPIIMSSSSIAPEAFPSEDLHNKTLSQQT 837
+ TA G +T+ +S T + S + A SE T +T
Sbjct: 1131 SETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSET 1183
Score = 43.5 bits (101), Expect = 0.002
Identities = 71/336 (21%), Positives = 132/336 (39%), Gaps = 19/336 (5%)
Query: 459 ETSICECQDENHKTIPEFSEEAESLTNSHEEPQIAPPEDNLESCVMMNDVLETLPHIEVK 518
ET+I + T+ E ++ + E E + E+ + ET
Sbjct: 1022 ETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGS-ETTTVSTTGSETTTASTAD 1080
Query: 519 IEGKSESPQEEMTVVIDQLEVCDSLIPSTSSMTHVSDTEHKESETAVETSTPKIKTGSSS 578
+E + S T + + T S T + TE E+ T TS+ ++
Sbjct: 1081 LETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTG 1140
Query: 579 LEGQFPNEGIAIDMELQSDPEEQLSENACISETSFSSESPEGACTSLPSPGGETQSTSEE 638
E ++ + + E + +A SE + + S EG+ T+ S G +T+
Sbjct: 1141 SEMTTVFTTVSETTTVSTIGSEATTSSAAGSEAT--TTSTEGSETTTASTAGSETTTA-- 1196
Query: 639 SCTPASLETTFCSEVSSTENTDKYNQRNSTDENFHASLMSEIS-PISTSPEISEASLMSN 697
+ A ETT S S T + ++ N + SE S P S E + A ++ +
Sbjct: 1197 --STAGSETTTASTAGSETTTAS---TSGSETNTACTTGSETSTPSSAGSETNTAFIIGS 1251
Query: 698 ---LPLTSEASPVSNLPLTSETSPMSDLPLTSETSSVSSMLLTSETTFVSSLPLPSETSP 754
+ T+ P + SET+ +S +T+ ++ +S + S TTFV + P
Sbjct: 1252 ETTIASTASLEPTATSLTGSETTTVS---ITASGATAASTTV-SSTTFVLTKATDVSIQP 1307
Query: 755 ISNSSINERMAHQQRKSPSVSEEPLSPQKDESSATA 790
I+N+ ++ R + S S ++P D +++ A
Sbjct: 1308 ITNTPMSGTRTTGTRLTAS-SSVTMAPGMDFTASAA 1342
Score = 40.8 bits (94), Expect = 0.015
Identities = 71/320 (22%), Positives = 121/320 (37%), Gaps = 36/320 (11%)
Query: 1269 SANTTISACNISMLKTIQGTDTPCIAIIPKCIESTPISATTEGSSISS-SMDDKQLLISS 1327
S+ TT++ S T T + I+ K E+T +A+T GS ++ S Q I S
Sbjct: 2 SSETTVAPAAGSNTTTASTTGSETTTILIKASETT--TASTAGSETTTPSPTGSQTTIVS 59
Query: 1328 SSASNLVST-----QYTSVPTPSIGNNLPNLSTSSVLIPPMGINNRFPSEKIAIPGSEEQ 1382
S S + +T + T+V + G +++ S + G + ++I G+E
Sbjct: 60 ISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSE----TTTVSITGTETT 115
Query: 1383 ATVSMGTTVRAALSCSDSVAVTDSLVAHPTVAMFTGNMLTINSYDSPPKLSAESLDKNSG 1442
+MG+ + S VT + + T G+ T +Y + + +A
Sbjct: 116 MVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSE-TTTAYTADSETTA-------- 166
Query: 1443 PRNRADNSGKPQQPPGGFAPAAINRSIPCKVIVDHSTTLTS--SLSLTVSVESSEASLDL 1500
A +G A + +I +TT+++ S + TVS SE +
Sbjct: 167 ----ASTTGSEMTT----VFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTAS 218
Query: 1501 QGRPVRTEASVQPVACPQVSVISRPEPVANEGIDHSSTFIAAS----AAKQDSKTLPATC 1556
T AS +VS V+ G + ++ S A +DSKT A+
Sbjct: 219 TAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTAST 278
Query: 1557 TSLRELPLVPDKLNEPTAPS 1576
T E +EPT S
Sbjct: 279 TGF-ETTAASTTGSEPTMAS 297
>gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1612
Score = 69.7 bits (169), Expect = 3e-11
Identities = 204/1076 (18%), Positives = 373/1076 (34%), Gaps = 117/1076 (10%)
Query: 541 DSLIPSTSSMTHVSDTEHKESETA-------VETSTPKIKTGSSSLEGQFPNE----GIA 589
++ + + S T + TE E+ TA ST +T ++S G P G
Sbjct: 243 ETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSE 302
Query: 590 IDMELQSDPEEQLSENACISETSFSSESPEGACTSLPSPGGETQSTSEESCTPASL---E 646
M PE A T+ + E S T ST+ T AS+ E
Sbjct: 303 TTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSE 362
Query: 647 TTFCSEVSS---TENTDKYNQRNSTDENFHASLMSEISPISTSPEISEASLMSNLPLTSE 703
T+ S S T +T+ ++ E A+ +S +T+ I+++ + SE
Sbjct: 363 TSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSE 422
Query: 704 ASPVSN--LPLTSETSPMSDLPLTSETSSVSSMLLT--SETTFVSSL--------PLPSE 751
+ VS T+ ++ S++ + S + S ++ T SETT V++ SE
Sbjct: 423 MTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSE 482
Query: 752 TSPISNSSINERMAHQQRKSPSVSEEPLSPQKDESSATAKPLGENLTSQQKNLSNT---- 807
T+ SN+ + + + S + E++A + E T + NT
Sbjct: 483 TTTASNTGLETTTVFTIGSDTTTA----STEGSETTAVSATGSEMTTVSTEGSENTTVST 538
Query: 808 --PEPIIMSSSSIAPEAFPSEDLHNKTLSQQTCKSHVDTEKPYPASIPELASTEMIKV-- 863
E +S++ + +E T+S ++ D+ + + A +E V
Sbjct: 539 TGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVST 598
Query: 864 ---KNHSVLQRTEKKVLPSPLELSVFSEGTDNKGNELPSAKLQDKQYISSVDKAPFSEGS 920
+N + + S + T + S + + +S+ D +
Sbjct: 599 ADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVST 658
Query: 921 RNKTHKQGSTQSRLETSHTSKSSEPSKSPDGIRNESRDSEISKRKTAEQHSFGICKEKRA 980
ST+ T+ ++ SE + S +G + + I+ +T + + G +
Sbjct: 659 TGSERTITSTEGSETTTVSATGSETTVSTEG--SGTTTVSITGSETTKVSTTGSETTTTS 716
Query: 981 RIEDDQSTRNISSSSPPEKEQPPREEPRVPPLKIQLSKIGPPFIIKSQ-PVSKPESRAST 1039
+ +T +I+ S E E + S+ S+ + S +T
Sbjct: 717 TEGSEITTASITGS---ETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETT 773
Query: 1040 STSVSGGRNTGARTLADIKARAQQARAQ--------REAAAAAAVAAAASIVSGA----- 1086
S+ G T A T+ + A ++ E A+ A+ + VS A
Sbjct: 774 MASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETI 833
Query: 1087 -MGSPGEGGKTRTLAHIKEQTKAKLFAKHQARAHLFQTSKETRLPPPLSSKEGPPNLEVS 1145
+ G T T E T A A S ET + S+ + E S
Sbjct: 834 PASTAGSETTTTTSTEGSETTTASTEGSETTTAS--TESSETTTATTIGSETTTASTEGS 891
Query: 1146 STPETKMEGSTGVIIVNPNCRSPSNKSAHLRETTTVLQQSLNPSKLPETATDLSVHSSDE 1205
T T EGS + S + + + +T ++ S T S S+
Sbjct: 892 ETTTTSTEGS--------ETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSEL 943
Query: 1206 NIPVSHLSEKI-VSSTSSENSSVPMLFNKNSVPVSVCSTAISGAIKEHPFVSSVDKSSVL 1264
+ SE I VS+ SE ++V + ++ +T S A E VS+ +
Sbjct: 944 TTVSTTGSETITVSAEGSETTTVTTMGSE--------TTTASTAGSETTTVSTAGSETTT 995
Query: 1265 MSVDSANTTISACNISMLKTIQGTDTPCIAIIPKCIESTPI-SATTEGSSISSSMDDKQL 1323
S++ + TT + S T+ T T + E+T + +A +E +++ ++ +
Sbjct: 996 ASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTT 1055
Query: 1324 LISSSSASNLVSTQYTSVPTPSIGNNLPNLSTSSVLIPPMGINNRFPSEKIAIPGSEEQA 1383
+ S + VST + T S +L T++V G + + GSE
Sbjct: 1056 TSTEGSETTTVSTTGSETTTASTA----DLETTTVSTSGSG------TTTASTAGSETTT 1105
Query: 1384 TVSMGTTVRAALSCSDSVAVTDSLVAHPTVAMFTGNMLTINSYDSPPKLSAESLDKNSGP 1443
G+ A + + + T A TG+ +T + ++ +
Sbjct: 1106 VYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATT 1165
Query: 1444 RNRADNSGKPQQPPGGFAPAAINRSIPCKVIVDHSTTLTSSLSLTVSVESSEASLDLQGR 1503
+ A + G A S T T+S T E++ AS
Sbjct: 1166 SSAAGSEATTTSTEGSETTTASTAG---------SETTTAS---TAGSETTTAS------ 1207
Query: 1504 PVRTEASVQPVACPQVSVISRPEPVANEGIDHSSTFIAASAAKQDSKTLPATCTSL 1559
T S AC S S P +E +++ I + + + +L T TSL
Sbjct: 1208 ---TSGSETNTACTTGSETSTPSSAGSE--TNTAFIIGSESTIASTASLEPTATSL 1258
Score = 68.6 bits (166), Expect = 7e-11
Identities = 177/921 (19%), Positives = 327/921 (35%), Gaps = 110/921 (11%)
Query: 547 TSSMTHVSDTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMELQSDPEEQLSENA 606
T S T + TE E TAV T+ + T S+ EG I + SD E
Sbjct: 409 TDSETTTTCTEGSEM-TAVSTTVFETTTAST--------EGSEITIASTSDSET------ 453
Query: 607 CISETSFSSESPEGACTSLPSPGGETQS---TSEESCTPAS--LETTFCSEVSSTENTDK 661
T+ S+E E T++ + G ET++ T E+ T ++ LETT + S T
Sbjct: 454 ----TTASTEGSE--TTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTAS 507
Query: 662 YNQRNSTDENFHASLMSEISP-------ISTSPEISEASLMSNLPLTSEASPVSNLPLTS 714
+T + S M+ +S +ST+ + + L T+ ++ S + S
Sbjct: 508 TEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVS 567
Query: 715 ETSPMSDLPLTSETSSVSSMLLTSETTFVSSLPLPSETSPISNSSINERMAHQQRKSPSV 774
T + T + + ++ SETT VS+ + T+ ++S S +
Sbjct: 568 TTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSA-------STTG 620
Query: 775 SEEPLSPQKDESSATAKPLGENLTSQQKNLSNTPEPIIMSSSSIAPEAFPS-EDLHNKTL 833
SE + + TA G T+ +S T M S++ + S E T+
Sbjct: 621 SETTTASTTSSETTTASTEGSETTT----VSTTDSETTMVSTTGSERTITSTEGSETTTV 676
Query: 834 SQQTCKSHVDTEKPYPASIPELASTEMIKVK---NHSVLQRTEKKVLPSPLELSVFSEGT 890
S ++ V TE ++ + +E KV + + TE + + +
Sbjct: 677 SATGSETTVSTEGSGTTTV-SITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTA 735
Query: 891 DNKGNELPSAKLQDKQYISSVDKAPFSEGSRNKTHKQGSTQSRLET-------------S 937
+G+E +A + + S+ + GS T S+++ + + S
Sbjct: 736 STEGSETTTASTEGSETTSAS-----TTGSETTTASTTSSETTMASIMGSETTMASTIGS 790
Query: 938 HTSKSSEPSKSPDGIRNESRDSEISKRKTAEQHSFGICKEKRARIEDDQS-TRNISSSSP 996
T+K S S + E+ ++ I+ +E + + S T +S+
Sbjct: 791 ETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEG 850
Query: 997 PEKEQPPREEPRVPPLKIQLSKIGPPFIIKSQPVS-KPESRASTSTSVSGGRNTGART-- 1053
E E + S+ I S+ + E +T+TS G T A T
Sbjct: 851 SETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEG 910
Query: 1054 -----LADIKARAQQARAQREAAAAAAVAAAASIVSGAMGSP-----GEGGKTRTLAHIK 1103
++ + A + A+ + GS EG +T T+ +
Sbjct: 911 SEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMG 970
Query: 1104 EQTKAKLFAKHQARAHLFQTSKETRLPPPLSSKEGPPNLEVSST-PETKMEGSTGVIIVN 1162
+T A + S+ T +S EG VSST ET +TG
Sbjct: 971 SETTTASTAGSETTTVSTAGSETTT-----ASIEGSETTTVSSTGSETTTVSTTGT---- 1021
Query: 1163 PNCRSPSNKSAHLRETTTVLQQSLNPSKLPETATDLSVHSSDENIPVSHLSEKIVSSTSS 1222
+ S ETTTV + + T ++ + S++ + + VS+T S
Sbjct: 1022 ----ETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTT------VSTTGS 1071
Query: 1223 ENSSVPMLFNKNSVPVSVCSTAISGAIKEHPFVSSVDKSSVLMSVDSANTTISACNISML 1282
E ++ + + + ST+ SG S+ + + + + TT ++ S
Sbjct: 1072 ETTTA----STADLETTTVSTSGSGTTT----ASTAGSETTTVYITGSKTTTASTEGSEA 1123
Query: 1283 KTIQGTDTPCIAIIPKCIESTPISAT-TEGSSISSSMDDKQLLISSSSASNLVSTQYTSV 1341
T+ T + E T + T +E +++S+ + ++ S + ST+ +
Sbjct: 1124 TTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSET 1183
Query: 1342 PTPSIGNNLPNLSTSSVLIPPMGINNRFPSEKIAIPGSEEQATVSMGTTVRAALSCSDSV 1401
T S + ++++ + + GSE S G+ A
Sbjct: 1184 TTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSES 1243
Query: 1402 AVTDSLVAHPTVAMFTGNMLT 1422
+ + PT TG+ T
Sbjct: 1244 TIASTASLEPTATSLTGSETT 1264
Score = 62.4 bits (150), Expect = 5e-09
Identities = 201/1062 (18%), Positives = 359/1062 (33%), Gaps = 147/1062 (13%)
Query: 542 SLIPSTSSMTHVSDTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMELQSDPEEQ 601
++ P+ S T + T E+ T + ++ ++ E P+ + + E
Sbjct: 6 TVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEI 65
Query: 602 LSENACISETSFSSESPEGACTSLPSPGGETQSTSEESCTPASLETTFCSEVSSTENTDK 661
+ + SE + S + G T+ + T ST+ T S+ T + VS+ +
Sbjct: 66 TTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETT 125
Query: 662 YNQRNSTDENFHASLMSEISPISTSPEISEASLMSNLPLTSEASPVSNLPLTSETSPMSD 721
N S++ ++ SE + +ST + + ++ T+ ++ S + +
Sbjct: 126 TNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETI 185
Query: 722 LPLT--SETSSVSSMLLTSETTFVSSLPLPSETSPISNSSINERMAHQQRKSPS-VSEEP 778
P T SET++VS+ SETT VS+ SET+ S AH + + S + E
Sbjct: 186 TPSTAGSETTTVSTA--GSETTTVSTTG--SETTTAST-------AHSETTAASTMGSET 234
Query: 779 LSPQKDESSATAKPLGENLTSQQKNLSNTPEPIIMSSSSIAPEAFPSEDLHNKTLSQQTC 838
S T G T+ S T +ED T S
Sbjct: 235 TKVSTAGSETTVSTAGSETTAASTEDSETNTAF-------------TEDSKTTTASTTGF 281
Query: 839 KSHVDTEKPYPASIPELASTEMIKVKNHSVLQRTEKKVLPSPLELS-VFSEGTDNKGNEL 897
++ T S P +AST + S + KV + E++ VF+ G++
Sbjct: 282 ET---TAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRAST 338
Query: 898 PSAKLQDKQYISSVDKAPFSEGSRNKTHKQGSTQSRLETSHTSKSSEPSKSPDGIRNESR 957
++ S GS T +T S T+ T S + S +G +
Sbjct: 339 VGSETTTVSTTGSETTTASIMGSETST--DSTTGSETTTASTEGSETTTASTEGSEATTV 396
Query: 958 DSEISKRKTAEQHSFGICKEKRARIEDDQSTRNISSSSPPEKEQPPREEPRVPPLKIQLS 1017
+ S+ T I D ++T + S +++
Sbjct: 397 STTGSETTTVS-------------ITDSETTTTCTEGS-------------------EMT 424
Query: 1018 KIGPPFIIKSQPVSKPESRASTSTSVSGGRNTGARTLADIKARAQQARAQREAAAAAAVA 1077
+ + + E T S S T A T + + A +
Sbjct: 425 AVSTT--VFETTTASTEGSEITIASTSDSETTTAST--------EGSETTTVTTAGSETK 474
Query: 1078 AAASIVSGAMGSPGEGGKTRTLAHIKEQTKAKLFAKHQARAHLFQTSKETRLPPPLSSKE 1137
A + S + G +T T+ I T + A S+ T + S E
Sbjct: 475 TAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTV-----STE 529
Query: 1138 GPPNLEVSST-PETKMEGSTGVIIVNPNCRSPSNKSAHLRETTTVLQQSLNPSKLPETAT 1196
G N VS+T ET +TG+ ETTT + + + T
Sbjct: 530 GSENTTVSTTGSETTTVSTTGL------------------ETTTTSTEGSEMTTVSTTGA 571
Query: 1197 DLSVHSSDENIPVSHLSEKIVSSTSSENSSVPMLFNKNSVPVSVCSTAISGAIKEHPFVS 1256
+ + S++ + S+ SE ++V ++N T S A E S
Sbjct: 572 ETTTDSTEGS------GTTAASTAGSETTTVSTADSEN--------TTASTADSETTSAS 617
Query: 1257 SVDKSSVLMSVDSANTTISACNISMLKTIQGTDTPCIAIIPKCIESTPISATTEGSSISS 1316
+ + S S+ TT ++ S T+ TD+ E+T +S T +I+S
Sbjct: 618 TTGSETTTASTTSSETTTASTEGSETTTVSTTDS----------ETTMVSTTGSERTITS 667
Query: 1317 SMDDKQLLISSSSASNLVSTQYTSVPTPSI-----------GNNLPNLSTSSVLIPPMGI 1365
+ + +S++ + VST+ + T SI G+ ST I I
Sbjct: 668 TEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASI 727
Query: 1366 NNRFPSEKIAIPGSEEQATVSMGTTVRAALSCSDSVAVTDSLVAHPTVAMFTGNMLTINS 1425
+ + GSE + G+ +A + + + T+A G+ T+ S
Sbjct: 728 TGS-ETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMAS 786
Query: 1426 ---YDSPPKLSAESLDKNSGPRNRADNSGKPQQPPGGFAPAAINRSIPCKVIVDHSTTLT 1482
++ +A S N A + +IP +TT T
Sbjct: 787 TIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTT 846
Query: 1483 SSLSLTVSVESSEASLDLQGRPVRTEASVQPVACPQVSVISRPEPVANEGIDHSSTFIAA 1542
S+ + S+E S + TE+S A ++ S + EG + ++T
Sbjct: 847 STEGSETTTASTEGS---ETTTASTESSETTTA---TTIGSETTTASTEGSETTTTSTEG 900
Query: 1543 S---AAKQDSKTLPATCTSLRELPLVPDKLNEPTAPSHNFAE 1581
S A + + T+ E + +E T S +E
Sbjct: 901 SETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSE 942
Score = 49.3 bits (116), Expect = 4e-05
Identities = 144/771 (18%), Positives = 258/771 (33%), Gaps = 98/771 (12%)
Query: 1039 TSTSVSGGRNTGARTLADIKARAQQARAQREAAAAAAVAAAASIVS------GAMGS--- 1089
T+TS +G NT + A A ++ + A + SI AMGS
Sbjct: 66 TTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETT 125
Query: 1090 ------------PGEGGKTRTLAHIKEQTKAKLFAKHQARAHLFQTSKETRLPPPLSSKE 1137
G +T T++ + +T A + A T E S+
Sbjct: 126 TNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTA-ASTTGSEMTTVFTAGSET 184
Query: 1138 GPPNLEVSSTPETKMEGSTGVIIVNPNCRSPSNKSAHLRETTTVLQQSLNPSKLPETATD 1197
P+ S T GS + + + +AH ETT +K+ ++
Sbjct: 185 ITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAH-SETTAASTMGSETTKVSTAGSE 243
Query: 1198 LSVHSSDENIPVSHLSEKIVSSTSSENSSVPMLFNKNSVPVSVC-----STAISGAIKEH 1252
+V ++ ++ S+E+S F ++S + +TA S E
Sbjct: 244 TTVSTAGSE----------TTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEP 293
Query: 1253 PFVSSVDKSSVLMSVDSANTTISACNISMLKTIQGTDTPCIAIIPKCIESTPISATTEGS 1312
S++ + + S TT + S + T+ + I E+T +S T +
Sbjct: 294 TMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSET 353
Query: 1313 SISSSMDDKQLLISSS-SASNLVSTQYTSVPTPSI-GNNLPNLSTSSVLIPPMGINNRFP 1370
+ +S M + S++ S + ST+ + T S G+ +ST+
Sbjct: 354 TTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTG-----------SE 402
Query: 1371 SEKIAIPGSEEQATVSMGTTVRAALSCSDSVAVTDSLVAHPTVAMFTGNMLTINSYDSPP 1430
+ ++I SE T + G+ + A + V T A G+ +TI S
Sbjct: 403 TTTVSITDSETTTTCTEGSEMTA----------VSTTVFETTTASTEGSEITIASTSDSE 452
Query: 1431 KLSAESLDKNSGPRNRADNSGKPQQPPGGFAPAAINRSIPCKVI--VDHSTT-------- 1480
+A + + A + K G A N + + + TT
Sbjct: 453 TTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSE 512
Query: 1481 -----LTSSLSLTVSVESSE-ASLDLQGRPVRT------EASVQPVACPQVSVISRPEPV 1528
T S TVS E SE ++ G T E + +++ +S
Sbjct: 513 TTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAE 572
Query: 1529 ANEGIDHSSTFIAASAAKQDSKTLPATCTSLRELPLVPDKLNEPTAPSHNFAEQARGPAP 1588
S AAS A ++ T+ +T S D +E T+ S +E A
Sbjct: 573 TTTDSTEGSGTTAASTAGSETTTV-STADSENTTASTAD--SETTSASTTGSETT--TAS 627
Query: 1589 FKSEADTTCSNQYNPSNRICWNDDG---MRSTG-QPLVTHSGSSKQKEYLEQSCPKAIKT 1644
S TT S + + + + D + +TG + +T + S+ + T
Sbjct: 628 TTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVST 687
Query: 1645 EHANYLNVSELHPRNLVTNVALPVKSELHEADKGFRMDTEDFPGPELPPPAAEGA----S 1700
E + VS T V+ + +G + T G E + EG+ +
Sbjct: 688 EGSGTTTVSITGSE--TTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTA 745
Query: 1701 SVQQTQNMKASTSSPMEEAISLATDALKRVPGAGSSGCRLSSVEANNPLVT 1751
S + ++ AST+ S + GS S++ + V+
Sbjct: 746 STEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVS 796
Score = 43.5 bits (101), Expect = 0.002
Identities = 93/473 (19%), Positives = 165/473 (34%), Gaps = 39/473 (8%)
Query: 373 TTGPNNAGAQSSSSCGTSGLPVSAQTALAEQQPKSMKSPASPEPGFCATLCPMVEIPPKD 432
TT + G++++S+ T +A T +E S+ G T+ +
Sbjct: 742 TTTASTEGSETTSASTTGSETTTASTTSSETTMASIM-------GSETTMASTIGSETTK 794
Query: 433 IMAELESEDILIPEESVIQEEIAEEVETSICECQDENHKTIPEFSEEAESLTNSHEEPQ- 491
+ + E S + IA + +TIP + +E+ T + E
Sbjct: 795 VSTASSKMTTVFTENS--ETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSE 852
Query: 492 -IAPPEDNLESCVMMNDVLETLPHIEVKIEGKSESPQEEMTVVIDQLEVCDSLIPSTSSM 550
+ E+ + ET + E + S + T + S
Sbjct: 853 TTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTS----------TEGSE 902
Query: 551 THVSDTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMEL---QSDPEEQLSENAC 607
T + TE E T ST +T ++S EG EL + E ++ +A
Sbjct: 903 TTTASTEGSEITTV---STTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAE 959
Query: 608 ISETSFSSESPEGACTSLPSPGGE---TQSTSEESCTPASLETTFCSEVSSTENTDKYNQ 664
SET+ + + G+ T+ S G T ST+ T AS+E + + VSST +
Sbjct: 960 GSETT--TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVS 1017
Query: 665 RNSTDENFHASLMSEISPISTSPEISEASLMSNLPLTSEASPVSNLPLTSETSPMSDLPL 724
T+ ++ SE + ++T+ + A + T+ ++ S S T +
Sbjct: 1018 TTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTAS 1077
Query: 725 TSETSSVSSMLLTSETTFVSSLPLPSETSPISNSSINERMAHQQRKSPSVSEEPLSPQKD 784
T++ + + S TT S+ + T I+ S S SE
Sbjct: 1078 TADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTT-------TASTEGSEATTVSTTS 1130
Query: 785 ESSATAKPLGENLTSQQKNLSNTPEPIIMSSSSIAPEAFPSEDLHNKTLSQQT 837
+ TA G +T+ +S T + S + A SE T +T
Sbjct: 1131 SETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSET 1183
Score = 41.6 bits (96), Expect = 0.009
Identities = 76/341 (22%), Positives = 131/341 (38%), Gaps = 39/341 (11%)
Query: 459 ETSICECQDENHKTIPEFSEEAESLTNSHEEPQIAPPEDNLESCVMMNDVLETLPHIEVK 518
ET+I + T+ E ++ + E E + E+ + ET
Sbjct: 1022 ETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGS-ETTTVSTTGSETTTASTAD 1080
Query: 519 IEGKSESPQEEMTVVIDQLEVCDSLIPSTSSMTHVSDTEHKESETAVETSTPKIKTGSSS 578
+E + S T + + T S T + TE E+ T TS+ +T ++S
Sbjct: 1081 LETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSS---ETTTAS 1137
Query: 579 LEGQFPNEGIAIDMELQSDPEEQLSENACISETSFSSESPEGACTSLPSPGGETQSTSEE 638
G E + +SET+ S A TS + G E +TS E
Sbjct: 1138 TTGS-----------------EMTTVFTTVSETTTVSTIGSEATTS-SAAGSEATTTSTE 1179
Query: 639 -----SCTPASLETTFCSEVSSTENTDKYNQRNSTDENFHASLMSEIS-PISTSPEISEA 692
+ + A ETT S S T + ++ N + SE S P S E + A
Sbjct: 1180 GSETTTASTAGSETTTASTAGSETTTAS---TSGSETNTACTTGSETSTPSSAGSETNTA 1236
Query: 693 SLM---SNLPLTSEASPVSNLPLTSETSPMSDLPLTSETSSVSSMLLTSETTFVSSLPLP 749
++ S + T+ P + SET+ +S +T+ ++ +S + S TTFV +
Sbjct: 1237 FIIGSESTIASTASLEPTATSLTGSETTTVS---ITASGATAASTTV-SSTTFVLTKATD 1292
Query: 750 SETSPISNSSINERMAHQQRKSPSVSEEPLSPQKDESSATA 790
PI+N+ ++ R + S S ++P D +++ A
Sbjct: 1293 VSIQPITNTPMSGTRTTGTRLTAS-SSVTMAPGMDFTASAA 1332
Score = 40.8 bits (94), Expect = 0.015
Identities = 71/320 (22%), Positives = 121/320 (37%), Gaps = 36/320 (11%)
Query: 1269 SANTTISACNISMLKTIQGTDTPCIAIIPKCIESTPISATTEGSSISS-SMDDKQLLISS 1327
S+ TT++ S T T + I+ K E+T +A+T GS ++ S Q I S
Sbjct: 2 SSETTVAPAAGSNTTTASTTGSETTTILIKASETT--TASTAGSETTTPSPTGSQTTIVS 59
Query: 1328 SSASNLVST-----QYTSVPTPSIGNNLPNLSTSSVLIPPMGINNRFPSEKIAIPGSEEQ 1382
S S + +T + T+V + G +++ S + G + ++I G+E
Sbjct: 60 ISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSE----TTTVSITGTETT 115
Query: 1383 ATVSMGTTVRAALSCSDSVAVTDSLVAHPTVAMFTGNMLTINSYDSPPKLSAESLDKNSG 1442
+MG+ + S VT + + T G+ T +Y + + +A
Sbjct: 116 MVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSE-TTTAYTADSETTA-------- 166
Query: 1443 PRNRADNSGKPQQPPGGFAPAAINRSIPCKVIVDHSTTLTS--SLSLTVSVESSEASLDL 1500
A +G A + +I +TT+++ S + TVS SE +
Sbjct: 167 ----ASTTGSEMTT----VFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTAS 218
Query: 1501 QGRPVRTEASVQPVACPQVSVISRPEPVANEGIDHSSTFIAAS----AAKQDSKTLPATC 1556
T AS +VS V+ G + ++ S A +DSKT A+
Sbjct: 219 TAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTAST 278
Query: 1557 TSLRELPLVPDKLNEPTAPS 1576
T E +EPT S
Sbjct: 279 TGF-ETTAASTTGSEPTMAS 297
>gi|239513940 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1521
Score = 69.7 bits (169), Expect = 3e-11
Identities = 204/1076 (18%), Positives = 373/1076 (34%), Gaps = 117/1076 (10%)
Query: 541 DSLIPSTSSMTHVSDTEHKESETA-------VETSTPKIKTGSSSLEGQFPNE----GIA 589
++ + + S T + TE E+ TA ST +T ++S G P G
Sbjct: 243 ETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSE 302
Query: 590 IDMELQSDPEEQLSENACISETSFSSESPEGACTSLPSPGGETQSTSEESCTPASL---E 646
M PE A T+ + E S T ST+ T AS+ E
Sbjct: 303 TTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSE 362
Query: 647 TTFCSEVSS---TENTDKYNQRNSTDENFHASLMSEISPISTSPEISEASLMSNLPLTSE 703
T+ S S T +T+ ++ E A+ +S +T+ I+++ + SE
Sbjct: 363 TSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSE 422
Query: 704 ASPVSN--LPLTSETSPMSDLPLTSETSSVSSMLLT--SETTFVSSL--------PLPSE 751
+ VS T+ ++ S++ + S + S ++ T SETT V++ SE
Sbjct: 423 MTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSE 482
Query: 752 TSPISNSSINERMAHQQRKSPSVSEEPLSPQKDESSATAKPLGENLTSQQKNLSNT---- 807
T+ SN+ + + + S + E++A + E T + NT
Sbjct: 483 TTTASNTGLETTTVFTIGSDTTTA----STEGSETTAVSATGSEMTTVSTEGSENTTVST 538
Query: 808 --PEPIIMSSSSIAPEAFPSEDLHNKTLSQQTCKSHVDTEKPYPASIPELASTEMIKV-- 863
E +S++ + +E T+S ++ D+ + + A +E V
Sbjct: 539 TGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVST 598
Query: 864 ---KNHSVLQRTEKKVLPSPLELSVFSEGTDNKGNELPSAKLQDKQYISSVDKAPFSEGS 920
+N + + S + T + S + + +S+ D +
Sbjct: 599 ADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVST 658
Query: 921 RNKTHKQGSTQSRLETSHTSKSSEPSKSPDGIRNESRDSEISKRKTAEQHSFGICKEKRA 980
ST+ T+ ++ SE + S +G + + I+ +T + + G +
Sbjct: 659 TGSERTITSTEGSETTTVSATGSETTVSTEG--SGTTTVSITGSETTKVSTTGSETTTTS 716
Query: 981 RIEDDQSTRNISSSSPPEKEQPPREEPRVPPLKIQLSKIGPPFIIKSQ-PVSKPESRAST 1039
+ +T +I+ S E E + S+ S+ + S +T
Sbjct: 717 TEGSEITTASITGS---ETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETT 773
Query: 1040 STSVSGGRNTGARTLADIKARAQQARAQ--------REAAAAAAVAAAASIVSGA----- 1086
S+ G T A T+ + A ++ E A+ A+ + VS A
Sbjct: 774 MASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETI 833
Query: 1087 -MGSPGEGGKTRTLAHIKEQTKAKLFAKHQARAHLFQTSKETRLPPPLSSKEGPPNLEVS 1145
+ G T T E T A A S ET + S+ + E S
Sbjct: 834 PASTAGSETTTTTSTEGSETTTASTEGSETTTAS--TESSETTTATTIGSETTTASTEGS 891
Query: 1146 STPETKMEGSTGVIIVNPNCRSPSNKSAHLRETTTVLQQSLNPSKLPETATDLSVHSSDE 1205
T T EGS + S + + + +T ++ S T S S+
Sbjct: 892 ETTTTSTEGS--------ETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSEL 943
Query: 1206 NIPVSHLSEKI-VSSTSSENSSVPMLFNKNSVPVSVCSTAISGAIKEHPFVSSVDKSSVL 1264
+ SE I VS+ SE ++V + ++ +T S A E VS+ +
Sbjct: 944 TTVSTTGSETITVSAEGSETTTVTTMGSE--------TTTASTAGSETTTVSTAGSETTT 995
Query: 1265 MSVDSANTTISACNISMLKTIQGTDTPCIAIIPKCIESTPI-SATTEGSSISSSMDDKQL 1323
S++ + TT + S T+ T T + E+T + +A +E +++ ++ +
Sbjct: 996 ASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTT 1055
Query: 1324 LISSSSASNLVSTQYTSVPTPSIGNNLPNLSTSSVLIPPMGINNRFPSEKIAIPGSEEQA 1383
+ S + VST + T S +L T++V G + + GSE
Sbjct: 1056 TSTEGSETTTVSTTGSETTTASTA----DLETTTVSTSGSG------TTTASTAGSETTT 1105
Query: 1384 TVSMGTTVRAALSCSDSVAVTDSLVAHPTVAMFTGNMLTINSYDSPPKLSAESLDKNSGP 1443
G+ A + + + T A TG+ +T + ++ +
Sbjct: 1106 VYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATT 1165
Query: 1444 RNRADNSGKPQQPPGGFAPAAINRSIPCKVIVDHSTTLTSSLSLTVSVESSEASLDLQGR 1503
+ A + G A S T T+S T E++ AS
Sbjct: 1166 SSAAGSEATTTSTEGSETTTASTAG---------SETTTAS---TAGSETTTAS------ 1207
Query: 1504 PVRTEASVQPVACPQVSVISRPEPVANEGIDHSSTFIAASAAKQDSKTLPATCTSL 1559
T S AC S S P +E +++ I + + + +L T TSL
Sbjct: 1208 ---TSGSETNTACTTGSETSTPSSAGSE--TNTAFIIGSESTIASTASLEPTATSL 1258
Score = 68.6 bits (166), Expect = 7e-11
Identities = 177/921 (19%), Positives = 327/921 (35%), Gaps = 110/921 (11%)
Query: 547 TSSMTHVSDTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMELQSDPEEQLSENA 606
T S T + TE E TAV T+ + T S+ EG I + SD E
Sbjct: 409 TDSETTTTCTEGSEM-TAVSTTVFETTTAST--------EGSEITIASTSDSET------ 453
Query: 607 CISETSFSSESPEGACTSLPSPGGETQS---TSEESCTPAS--LETTFCSEVSSTENTDK 661
T+ S+E E T++ + G ET++ T E+ T ++ LETT + S T
Sbjct: 454 ----TTASTEGSE--TTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTAS 507
Query: 662 YNQRNSTDENFHASLMSEISP-------ISTSPEISEASLMSNLPLTSEASPVSNLPLTS 714
+T + S M+ +S +ST+ + + L T+ ++ S + S
Sbjct: 508 TEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVS 567
Query: 715 ETSPMSDLPLTSETSSVSSMLLTSETTFVSSLPLPSETSPISNSSINERMAHQQRKSPSV 774
T + T + + ++ SETT VS+ + T+ ++S S +
Sbjct: 568 TTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSA-------STTG 620
Query: 775 SEEPLSPQKDESSATAKPLGENLTSQQKNLSNTPEPIIMSSSSIAPEAFPS-EDLHNKTL 833
SE + + TA G T+ +S T M S++ + S E T+
Sbjct: 621 SETTTASTTSSETTTASTEGSETTT----VSTTDSETTMVSTTGSERTITSTEGSETTTV 676
Query: 834 SQQTCKSHVDTEKPYPASIPELASTEMIKVK---NHSVLQRTEKKVLPSPLELSVFSEGT 890
S ++ V TE ++ + +E KV + + TE + + +
Sbjct: 677 SATGSETTVSTEGSGTTTV-SITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTA 735
Query: 891 DNKGNELPSAKLQDKQYISSVDKAPFSEGSRNKTHKQGSTQSRLET-------------S 937
+G+E +A + + S+ + GS T S+++ + + S
Sbjct: 736 STEGSETTTASTEGSETTSAS-----TTGSETTTASTTSSETTMASIMGSETTMASTIGS 790
Query: 938 HTSKSSEPSKSPDGIRNESRDSEISKRKTAEQHSFGICKEKRARIEDDQS-TRNISSSSP 996
T+K S S + E+ ++ I+ +E + + S T +S+
Sbjct: 791 ETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEG 850
Query: 997 PEKEQPPREEPRVPPLKIQLSKIGPPFIIKSQPVS-KPESRASTSTSVSGGRNTGART-- 1053
E E + S+ I S+ + E +T+TS G T A T
Sbjct: 851 SETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEG 910
Query: 1054 -----LADIKARAQQARAQREAAAAAAVAAAASIVSGAMGSP-----GEGGKTRTLAHIK 1103
++ + A + A+ + GS EG +T T+ +
Sbjct: 911 SEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMG 970
Query: 1104 EQTKAKLFAKHQARAHLFQTSKETRLPPPLSSKEGPPNLEVSST-PETKMEGSTGVIIVN 1162
+T A + S+ T +S EG VSST ET +TG
Sbjct: 971 SETTTASTAGSETTTVSTAGSETTT-----ASIEGSETTTVSSTGSETTTVSTTGT---- 1021
Query: 1163 PNCRSPSNKSAHLRETTTVLQQSLNPSKLPETATDLSVHSSDENIPVSHLSEKIVSSTSS 1222
+ S ETTTV + + T ++ + S++ + + VS+T S
Sbjct: 1022 ----ETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTT------VSTTGS 1071
Query: 1223 ENSSVPMLFNKNSVPVSVCSTAISGAIKEHPFVSSVDKSSVLMSVDSANTTISACNISML 1282
E ++ + + + ST+ SG S+ + + + + TT ++ S
Sbjct: 1072 ETTTA----STADLETTTVSTSGSGTTT----ASTAGSETTTVYITGSKTTTASTEGSEA 1123
Query: 1283 KTIQGTDTPCIAIIPKCIESTPISAT-TEGSSISSSMDDKQLLISSSSASNLVSTQYTSV 1341
T+ T + E T + T +E +++S+ + ++ S + ST+ +
Sbjct: 1124 TTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSET 1183
Query: 1342 PTPSIGNNLPNLSTSSVLIPPMGINNRFPSEKIAIPGSEEQATVSMGTTVRAALSCSDSV 1401
T S + ++++ + + GSE S G+ A
Sbjct: 1184 TTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSES 1243
Query: 1402 AVTDSLVAHPTVAMFTGNMLT 1422
+ + PT TG+ T
Sbjct: 1244 TIASTASLEPTATSLTGSETT 1264
Score = 62.4 bits (150), Expect = 5e-09
Identities = 201/1062 (18%), Positives = 359/1062 (33%), Gaps = 147/1062 (13%)
Query: 542 SLIPSTSSMTHVSDTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMELQSDPEEQ 601
++ P+ S T + T E+ T + ++ ++ E P+ + + E
Sbjct: 6 TVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEI 65
Query: 602 LSENACISETSFSSESPEGACTSLPSPGGETQSTSEESCTPASLETTFCSEVSSTENTDK 661
+ + SE + S + G T+ + T ST+ T S+ T + VS+ +
Sbjct: 66 TTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETT 125
Query: 662 YNQRNSTDENFHASLMSEISPISTSPEISEASLMSNLPLTSEASPVSNLPLTSETSPMSD 721
N S++ ++ SE + +ST + + ++ T+ ++ S + +
Sbjct: 126 TNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETI 185
Query: 722 LPLT--SETSSVSSMLLTSETTFVSSLPLPSETSPISNSSINERMAHQQRKSPS-VSEEP 778
P T SET++VS+ SETT VS+ SET+ S AH + + S + E
Sbjct: 186 TPSTAGSETTTVSTA--GSETTTVSTTG--SETTTAST-------AHSETTAASTMGSET 234
Query: 779 LSPQKDESSATAKPLGENLTSQQKNLSNTPEPIIMSSSSIAPEAFPSEDLHNKTLSQQTC 838
S T G T+ S T +ED T S
Sbjct: 235 TKVSTAGSETTVSTAGSETTAASTEDSETNTAF-------------TEDSKTTTASTTGF 281
Query: 839 KSHVDTEKPYPASIPELASTEMIKVKNHSVLQRTEKKVLPSPLELS-VFSEGTDNKGNEL 897
++ T S P +AST + S + KV + E++ VF+ G++
Sbjct: 282 ET---TAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRAST 338
Query: 898 PSAKLQDKQYISSVDKAPFSEGSRNKTHKQGSTQSRLETSHTSKSSEPSKSPDGIRNESR 957
++ S GS T +T S T+ T S + S +G +
Sbjct: 339 VGSETTTVSTTGSETTTASIMGSETST--DSTTGSETTTASTEGSETTTASTEGSEATTV 396
Query: 958 DSEISKRKTAEQHSFGICKEKRARIEDDQSTRNISSSSPPEKEQPPREEPRVPPLKIQLS 1017
+ S+ T I D ++T + S +++
Sbjct: 397 STTGSETTTVS-------------ITDSETTTTCTEGS-------------------EMT 424
Query: 1018 KIGPPFIIKSQPVSKPESRASTSTSVSGGRNTGARTLADIKARAQQARAQREAAAAAAVA 1077
+ + + E T S S T A T + + A +
Sbjct: 425 AVSTT--VFETTTASTEGSEITIASTSDSETTTAST--------EGSETTTVTTAGSETK 474
Query: 1078 AAASIVSGAMGSPGEGGKTRTLAHIKEQTKAKLFAKHQARAHLFQTSKETRLPPPLSSKE 1137
A + S + G +T T+ I T + A S+ T + S E
Sbjct: 475 TAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTV-----STE 529
Query: 1138 GPPNLEVSST-PETKMEGSTGVIIVNPNCRSPSNKSAHLRETTTVLQQSLNPSKLPETAT 1196
G N VS+T ET +TG+ ETTT + + + T
Sbjct: 530 GSENTTVSTTGSETTTVSTTGL------------------ETTTTSTEGSEMTTVSTTGA 571
Query: 1197 DLSVHSSDENIPVSHLSEKIVSSTSSENSSVPMLFNKNSVPVSVCSTAISGAIKEHPFVS 1256
+ + S++ + S+ SE ++V ++N T S A E S
Sbjct: 572 ETTTDSTEGS------GTTAASTAGSETTTVSTADSEN--------TTASTADSETTSAS 617
Query: 1257 SVDKSSVLMSVDSANTTISACNISMLKTIQGTDTPCIAIIPKCIESTPISATTEGSSISS 1316
+ + S S+ TT ++ S T+ TD+ E+T +S T +I+S
Sbjct: 618 TTGSETTTASTTSSETTTASTEGSETTTVSTTDS----------ETTMVSTTGSERTITS 667
Query: 1317 SMDDKQLLISSSSASNLVSTQYTSVPTPSI-----------GNNLPNLSTSSVLIPPMGI 1365
+ + +S++ + VST+ + T SI G+ ST I I
Sbjct: 668 TEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASI 727
Query: 1366 NNRFPSEKIAIPGSEEQATVSMGTTVRAALSCSDSVAVTDSLVAHPTVAMFTGNMLTINS 1425
+ + GSE + G+ +A + + + T+A G+ T+ S
Sbjct: 728 TGS-ETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMAS 786
Query: 1426 ---YDSPPKLSAESLDKNSGPRNRADNSGKPQQPPGGFAPAAINRSIPCKVIVDHSTTLT 1482
++ +A S N A + +IP +TT T
Sbjct: 787 TIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTT 846
Query: 1483 SSLSLTVSVESSEASLDLQGRPVRTEASVQPVACPQVSVISRPEPVANEGIDHSSTFIAA 1542
S+ + S+E S + TE+S A ++ S + EG + ++T
Sbjct: 847 STEGSETTTASTEGS---ETTTASTESSETTTA---TTIGSETTTASTEGSETTTTSTEG 900
Query: 1543 S---AAKQDSKTLPATCTSLRELPLVPDKLNEPTAPSHNFAE 1581
S A + + T+ E + +E T S +E
Sbjct: 901 SETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSE 942
Score = 49.3 bits (116), Expect = 4e-05
Identities = 144/771 (18%), Positives = 258/771 (33%), Gaps = 98/771 (12%)
Query: 1039 TSTSVSGGRNTGARTLADIKARAQQARAQREAAAAAAVAAAASIVS------GAMGS--- 1089
T+TS +G NT + A A ++ + A + SI AMGS
Sbjct: 66 TTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETT 125
Query: 1090 ------------PGEGGKTRTLAHIKEQTKAKLFAKHQARAHLFQTSKETRLPPPLSSKE 1137
G +T T++ + +T A + A T E S+
Sbjct: 126 TNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTA-ASTTGSEMTTVFTAGSET 184
Query: 1138 GPPNLEVSSTPETKMEGSTGVIIVNPNCRSPSNKSAHLRETTTVLQQSLNPSKLPETATD 1197
P+ S T GS + + + +AH ETT +K+ ++
Sbjct: 185 ITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAH-SETTAASTMGSETTKVSTAGSE 243
Query: 1198 LSVHSSDENIPVSHLSEKIVSSTSSENSSVPMLFNKNSVPVSVC-----STAISGAIKEH 1252
+V ++ ++ S+E+S F ++S + +TA S E
Sbjct: 244 TTVSTAGSE----------TTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEP 293
Query: 1253 PFVSSVDKSSVLMSVDSANTTISACNISMLKTIQGTDTPCIAIIPKCIESTPISATTEGS 1312
S++ + + S TT + S + T+ + I E+T +S T +
Sbjct: 294 TMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSET 353
Query: 1313 SISSSMDDKQLLISSS-SASNLVSTQYTSVPTPSI-GNNLPNLSTSSVLIPPMGINNRFP 1370
+ +S M + S++ S + ST+ + T S G+ +ST+
Sbjct: 354 TTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTG-----------SE 402
Query: 1371 SEKIAIPGSEEQATVSMGTTVRAALSCSDSVAVTDSLVAHPTVAMFTGNMLTINSYDSPP 1430
+ ++I SE T + G+ + A + V T A G+ +TI S
Sbjct: 403 TTTVSITDSETTTTCTEGSEMTA----------VSTTVFETTTASTEGSEITIASTSDSE 452
Query: 1431 KLSAESLDKNSGPRNRADNSGKPQQPPGGFAPAAINRSIPCKVI--VDHSTT-------- 1480
+A + + A + K G A N + + + TT
Sbjct: 453 TTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSE 512
Query: 1481 -----LTSSLSLTVSVESSE-ASLDLQGRPVRT------EASVQPVACPQVSVISRPEPV 1528
T S TVS E SE ++ G T E + +++ +S
Sbjct: 513 TTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAE 572
Query: 1529 ANEGIDHSSTFIAASAAKQDSKTLPATCTSLRELPLVPDKLNEPTAPSHNFAEQARGPAP 1588
S AAS A ++ T+ +T S D +E T+ S +E A
Sbjct: 573 TTTDSTEGSGTTAASTAGSETTTV-STADSENTTASTAD--SETTSASTTGSETT--TAS 627
Query: 1589 FKSEADTTCSNQYNPSNRICWNDDG---MRSTG-QPLVTHSGSSKQKEYLEQSCPKAIKT 1644
S TT S + + + + D + +TG + +T + S+ + T
Sbjct: 628 TTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVST 687
Query: 1645 EHANYLNVSELHPRNLVTNVALPVKSELHEADKGFRMDTEDFPGPELPPPAAEGA----S 1700
E + VS T V+ + +G + T G E + EG+ +
Sbjct: 688 EGSGTTTVSITGSE--TTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTA 745
Query: 1701 SVQQTQNMKASTSSPMEEAISLATDALKRVPGAGSSGCRLSSVEANNPLVT 1751
S + ++ AST+ S + GS S++ + V+
Sbjct: 746 STEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVS 796
Score = 43.5 bits (101), Expect = 0.002
Identities = 93/473 (19%), Positives = 165/473 (34%), Gaps = 39/473 (8%)
Query: 373 TTGPNNAGAQSSSSCGTSGLPVSAQTALAEQQPKSMKSPASPEPGFCATLCPMVEIPPKD 432
TT + G++++S+ T +A T +E S+ G T+ +
Sbjct: 742 TTTASTEGSETTSASTTGSETTTASTTSSETTMASIM-------GSETTMASTIGSETTK 794
Query: 433 IMAELESEDILIPEESVIQEEIAEEVETSICECQDENHKTIPEFSEEAESLTNSHEEPQ- 491
+ + E S + IA + +TIP + +E+ T + E
Sbjct: 795 VSTASSKMTTVFTENS--ETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSE 852
Query: 492 -IAPPEDNLESCVMMNDVLETLPHIEVKIEGKSESPQEEMTVVIDQLEVCDSLIPSTSSM 550
+ E+ + ET + E + S + T + S
Sbjct: 853 TTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTS----------TEGSE 902
Query: 551 THVSDTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMEL---QSDPEEQLSENAC 607
T + TE E T ST +T ++S EG EL + E ++ +A
Sbjct: 903 TTTASTEGSEITTV---STTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAE 959
Query: 608 ISETSFSSESPEGACTSLPSPGGE---TQSTSEESCTPASLETTFCSEVSSTENTDKYNQ 664
SET+ + + G+ T+ S G T ST+ T AS+E + + VSST +
Sbjct: 960 GSETT--TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVS 1017
Query: 665 RNSTDENFHASLMSEISPISTSPEISEASLMSNLPLTSEASPVSNLPLTSETSPMSDLPL 724
T+ ++ SE + ++T+ + A + T+ ++ S S T +
Sbjct: 1018 TTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTAS 1077
Query: 725 TSETSSVSSMLLTSETTFVSSLPLPSETSPISNSSINERMAHQQRKSPSVSEEPLSPQKD 784
T++ + + S TT S+ + T I+ S S SE
Sbjct: 1078 TADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTT-------TASTEGSEATTVSTTS 1130
Query: 785 ESSATAKPLGENLTSQQKNLSNTPEPIIMSSSSIAPEAFPSEDLHNKTLSQQT 837
+ TA G +T+ +S T + S + A SE T +T
Sbjct: 1131 SETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSET 1183
Score = 41.6 bits (96), Expect = 0.009
Identities = 76/341 (22%), Positives = 131/341 (38%), Gaps = 39/341 (11%)
Query: 459 ETSICECQDENHKTIPEFSEEAESLTNSHEEPQIAPPEDNLESCVMMNDVLETLPHIEVK 518
ET+I + T+ E ++ + E E + E+ + ET
Sbjct: 1022 ETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGS-ETTTVSTTGSETTTASTAD 1080
Query: 519 IEGKSESPQEEMTVVIDQLEVCDSLIPSTSSMTHVSDTEHKESETAVETSTPKIKTGSSS 578
+E + S T + + T S T + TE E+ T TS+ +T ++S
Sbjct: 1081 LETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSS---ETTTAS 1137
Query: 579 LEGQFPNEGIAIDMELQSDPEEQLSENACISETSFSSESPEGACTSLPSPGGETQSTSEE 638
G E + +SET+ S A TS + G E +TS E
Sbjct: 1138 TTGS-----------------EMTTVFTTVSETTTVSTIGSEATTS-SAAGSEATTTSTE 1179
Query: 639 -----SCTPASLETTFCSEVSSTENTDKYNQRNSTDENFHASLMSEIS-PISTSPEISEA 692
+ + A ETT S S T + ++ N + SE S P S E + A
Sbjct: 1180 GSETTTASTAGSETTTASTAGSETTTAS---TSGSETNTACTTGSETSTPSSAGSETNTA 1236
Query: 693 SLM---SNLPLTSEASPVSNLPLTSETSPMSDLPLTSETSSVSSMLLTSETTFVSSLPLP 749
++ S + T+ P + SET+ +S +T+ ++ +S + S TTFV +
Sbjct: 1237 FIIGSESTIASTASLEPTATSLTGSETTTVS---ITASGATAASTTV-SSTTFVLTKATD 1292
Query: 750 SETSPISNSSINERMAHQQRKSPSVSEEPLSPQKDESSATA 790
PI+N+ ++ R + S S ++P D +++ A
Sbjct: 1293 VSIQPITNTPMSGTRTTGTRLTAS-SSVTMAPGMDFTASAA 1332
Score = 40.8 bits (94), Expect = 0.015
Identities = 71/320 (22%), Positives = 121/320 (37%), Gaps = 36/320 (11%)
Query: 1269 SANTTISACNISMLKTIQGTDTPCIAIIPKCIESTPISATTEGSSISS-SMDDKQLLISS 1327
S+ TT++ S T T + I+ K E+T +A+T GS ++ S Q I S
Sbjct: 2 SSETTVAPAAGSNTTTASTTGSETTTILIKASETT--TASTAGSETTTPSPTGSQTTIVS 59
Query: 1328 SSASNLVST-----QYTSVPTPSIGNNLPNLSTSSVLIPPMGINNRFPSEKIAIPGSEEQ 1382
S S + +T + T+V + G +++ S + G + ++I G+E
Sbjct: 60 ISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSE----TTTVSITGTETT 115
Query: 1383 ATVSMGTTVRAALSCSDSVAVTDSLVAHPTVAMFTGNMLTINSYDSPPKLSAESLDKNSG 1442
+MG+ + S VT + + T G+ T +Y + + +A
Sbjct: 116 MVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSE-TTTAYTADSETTA-------- 166
Query: 1443 PRNRADNSGKPQQPPGGFAPAAINRSIPCKVIVDHSTTLTS--SLSLTVSVESSEASLDL 1500
A +G A + +I +TT+++ S + TVS SE +
Sbjct: 167 ----ASTTGSEMTT----VFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTAS 218
Query: 1501 QGRPVRTEASVQPVACPQVSVISRPEPVANEGIDHSSTFIAAS----AAKQDSKTLPATC 1556
T AS +VS V+ G + ++ S A +DSKT A+
Sbjct: 219 TAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTAST 278
Query: 1557 TSLRELPLVPDKLNEPTAPS 1576
T E +EPT S
Sbjct: 279 TGF-ETTAASTTGSEPTMAS 297
>gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1521
Score = 69.3 bits (168), Expect = 4e-11
Identities = 204/1076 (18%), Positives = 372/1076 (34%), Gaps = 117/1076 (10%)
Query: 541 DSLIPSTSSMTHVSDTEHKESETA-------VETSTPKIKTGSSSLEGQFPNE----GIA 589
++ + + S T + TE E+ TA ST +T ++S G P G
Sbjct: 243 ETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSE 302
Query: 590 IDMELQSDPEEQLSENACISETSFSSESPEGACTSLPSPGGETQSTSEESCTPASL---E 646
M PE A T+ + E S T ST+ T AS+ E
Sbjct: 303 TTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSE 362
Query: 647 TTFCSEVSS---TENTDKYNQRNSTDENFHASLMSEISPISTSPEISEASLMSNLPLTSE 703
T+ S S T +T+ ++ E A+ +S +T+ I+++ + SE
Sbjct: 363 TSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSE 422
Query: 704 ASPVSN--LPLTSETSPMSDLPLTSETSSVSSMLLT--SETTFVSSL--------PLPSE 751
+ VS T+ ++ S++ + S + S ++ T SETT V++ SE
Sbjct: 423 MTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSE 482
Query: 752 TSPISNSSINERMAHQQRKSPSVSEEPLSPQKDESSATAKPLGENLTSQQKNLSNT---- 807
T+ SN+ + + + S + E++A + E T + NT
Sbjct: 483 TTTASNTGLETTTVFTIGSDTTTA----STEGSETTAVSATGSEMTTVSTEGSENTTVST 538
Query: 808 --PEPIIMSSSSIAPEAFPSEDLHNKTLSQQTCKSHVDTEKPYPASIPELASTEMIKV-- 863
E +S++ + +E T+S ++ D+ + + A +E V
Sbjct: 539 TGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVST 598
Query: 864 ---KNHSVLQRTEKKVLPSPLELSVFSEGTDNKGNELPSAKLQDKQYISSVDKAPFSEGS 920
+N + + S + T + S + + +S+ D +
Sbjct: 599 ADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVST 658
Query: 921 RNKTHKQGSTQSRLETSHTSKSSEPSKSPDGIRNESRDSEISKRKTAEQHSFGICKEKRA 980
ST+ T+ ++ SE + S +G + + I+ +T + + G +
Sbjct: 659 TGSERTITSTEGSETTTVSATGSETTVSTEG--SGTTTVSITGSETTKVSTTGSETTTTS 716
Query: 981 RIEDDQSTRNISSSSPPEKEQPPREEPRVPPLKIQLSKIGPPFIIKSQ-PVSKPESRAST 1039
+ +T +I+ S E E + S+ S+ + S +T
Sbjct: 717 TEGSEITTASITGS---ETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETT 773
Query: 1040 STSVSGGRNTGARTLADIKARAQQARAQ--------REAAAAAAVAAAASIVSGA----- 1086
S+ G T A T+ + A ++ E A+ A+ + VS A
Sbjct: 774 MASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETI 833
Query: 1087 -MGSPGEGGKTRTLAHIKEQTKAKLFAKHQARAHLFQTSKETRLPPPLSSKEGPPNLEVS 1145
+ G T T E T A A S ET + S+ + E S
Sbjct: 834 PASTAGSETTTTTSTEGSETTTASTEGSETTTAS--TESSETTTATTIGSETTTASTEGS 891
Query: 1146 STPETKMEGSTGVIIVNPNCRSPSNKSAHLRETTTVLQQSLNPSKLPETATDLSVHSSDE 1205
T T EGS + S + + + +T ++ S T S S+
Sbjct: 892 ETTTTSTEGS--------ETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSEL 943
Query: 1206 NIPVSHLSEKI-VSSTSSENSSVPMLFNKNSVPVSVCSTAISGAIKEHPFVSSVDKSSVL 1264
+ SE I VS+ SE ++V + ++ +T S A E VS+ +
Sbjct: 944 TTVSTTGSETITVSAEGSETTTVTTMGSE--------TTTASTAGSETTTVSTAGSETTT 995
Query: 1265 MSVDSANTTISACNISMLKTIQGTDTPCIAIIPKCIESTPI-SATTEGSSISSSMDDKQL 1323
S++ + TT + S T+ T T + E+T + +A +E +++ ++ +
Sbjct: 996 ASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTT 1055
Query: 1324 LISSSSASNLVSTQYTSVPTPSIGNNLPNLSTSSVLIPPMGINNRFPSEKIAIPGSEEQA 1383
+ S + VST + T S +L T++V G + + GSE
Sbjct: 1056 TSTEGSETTTVSTTGSETTTASTA----DLETTTVSTSGSG------TTTASTAGSETTT 1105
Query: 1384 TVSMGTTVRAALSCSDSVAVTDSLVAHPTVAMFTGNMLTINSYDSPPKLSAESLDKNSGP 1443
G+ A + + + T A TG+ +T + ++ +
Sbjct: 1106 VYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATT 1165
Query: 1444 RNRADNSGKPQQPPGGFAPAAINRSIPCKVIVDHSTTLTSSLSLTVSVESSEASLDLQGR 1503
+ A + G A S T T+S T E++ AS
Sbjct: 1166 SSAAGSEATTTSTEGSETTTASTAG---------SETTTAS---TAGSETTTAS------ 1207
Query: 1504 PVRTEASVQPVACPQVSVISRPEPVANEGIDHSSTFIAASAAKQDSKTLPATCTSL 1559
T S AC S S P +E +++ I + + +L T TSL
Sbjct: 1208 ---TSGSETNTACTTGSETSTPSSAGSE--TNTAFIIGSETTIASTASLEPTATSL 1258
Score = 69.3 bits (168), Expect = 4e-11
Identities = 177/921 (19%), Positives = 327/921 (35%), Gaps = 110/921 (11%)
Query: 547 TSSMTHVSDTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMELQSDPEEQLSENA 606
T S T + TE E TAV T+ + T S+ EG I + SD E
Sbjct: 409 TDSETTTTCTEGSEM-TAVSTTVFETTTAST--------EGSEITIASTSDSET------ 453
Query: 607 CISETSFSSESPEGACTSLPSPGGETQS---TSEESCTPAS--LETTFCSEVSSTENTDK 661
T+ S+E E T++ + G ET++ T E+ T ++ LETT + S T
Sbjct: 454 ----TTASTEGSE--TTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTAS 507
Query: 662 YNQRNSTDENFHASLMSEISP-------ISTSPEISEASLMSNLPLTSEASPVSNLPLTS 714
+T + S M+ +S +ST+ + + L T+ ++ S + S
Sbjct: 508 TEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVS 567
Query: 715 ETSPMSDLPLTSETSSVSSMLLTSETTFVSSLPLPSETSPISNSSINERMAHQQRKSPSV 774
T + T + + ++ SETT VS+ + T+ ++S S +
Sbjct: 568 TTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSA-------STTG 620
Query: 775 SEEPLSPQKDESSATAKPLGENLTSQQKNLSNTPEPIIMSSSSIAPEAFPS-EDLHNKTL 833
SE + + TA G T+ +S T M S++ + S E T+
Sbjct: 621 SETTTASTTSSETTTASTEGSETTT----VSTTDSETTMVSTTGSERTITSTEGSETTTV 676
Query: 834 SQQTCKSHVDTEKPYPASIPELASTEMIKVK---NHSVLQRTEKKVLPSPLELSVFSEGT 890
S ++ V TE ++ + +E KV + + TE + + +
Sbjct: 677 SATGSETTVSTEGSGTTTV-SITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTA 735
Query: 891 DNKGNELPSAKLQDKQYISSVDKAPFSEGSRNKTHKQGSTQSRLET-------------S 937
+G+E +A + + S+ + GS T S+++ + + S
Sbjct: 736 STEGSETTTASTEGSETTSAS-----TTGSETTTASTTSSETTMASIMGSETTMASTIGS 790
Query: 938 HTSKSSEPSKSPDGIRNESRDSEISKRKTAEQHSFGICKEKRARIEDDQS-TRNISSSSP 996
T+K S S + E+ ++ I+ +E + + S T +S+
Sbjct: 791 ETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEG 850
Query: 997 PEKEQPPREEPRVPPLKIQLSKIGPPFIIKSQPVS-KPESRASTSTSVSGGRNTGART-- 1053
E E + S+ I S+ + E +T+TS G T A T
Sbjct: 851 SETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEG 910
Query: 1054 -----LADIKARAQQARAQREAAAAAAVAAAASIVSGAMGSP-----GEGGKTRTLAHIK 1103
++ + A + A+ + GS EG +T T+ +
Sbjct: 911 SEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMG 970
Query: 1104 EQTKAKLFAKHQARAHLFQTSKETRLPPPLSSKEGPPNLEVSST-PETKMEGSTGVIIVN 1162
+T A + S+ T +S EG VSST ET +TG
Sbjct: 971 SETTTASTAGSETTTVSTAGSETTT-----ASIEGSETTTVSSTGSETTTVSTTGT---- 1021
Query: 1163 PNCRSPSNKSAHLRETTTVLQQSLNPSKLPETATDLSVHSSDENIPVSHLSEKIVSSTSS 1222
+ S ETTTV + + T ++ + S++ + + VS+T S
Sbjct: 1022 ----ETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTT------VSTTGS 1071
Query: 1223 ENSSVPMLFNKNSVPVSVCSTAISGAIKEHPFVSSVDKSSVLMSVDSANTTISACNISML 1282
E ++ + + + ST+ SG S+ + + + + TT ++ S
Sbjct: 1072 ETTTA----STADLETTTVSTSGSGTTT----ASTAGSETTTVYITGSKTTTASTEGSEA 1123
Query: 1283 KTIQGTDTPCIAIIPKCIESTPISAT-TEGSSISSSMDDKQLLISSSSASNLVSTQYTSV 1341
T+ T + E T + T +E +++S+ + ++ S + ST+ +
Sbjct: 1124 TTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSET 1183
Query: 1342 PTPSIGNNLPNLSTSSVLIPPMGINNRFPSEKIAIPGSEEQATVSMGTTVRAALSCSDSV 1401
T S + ++++ + + GSE S G+ A
Sbjct: 1184 TTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSET 1243
Query: 1402 AVTDSLVAHPTVAMFTGNMLT 1422
+ + PT TG+ T
Sbjct: 1244 TIASTASLEPTATSLTGSETT 1264
Score = 62.4 bits (150), Expect = 5e-09
Identities = 201/1062 (18%), Positives = 359/1062 (33%), Gaps = 147/1062 (13%)
Query: 542 SLIPSTSSMTHVSDTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMELQSDPEEQ 601
++ P+ S T + T E+ T + ++ ++ E P+ + + E
Sbjct: 6 TVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEI 65
Query: 602 LSENACISETSFSSESPEGACTSLPSPGGETQSTSEESCTPASLETTFCSEVSSTENTDK 661
+ + SE + S + G T+ + T ST+ T S+ T + VS+ +
Sbjct: 66 TTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETT 125
Query: 662 YNQRNSTDENFHASLMSEISPISTSPEISEASLMSNLPLTSEASPVSNLPLTSETSPMSD 721
N S++ ++ SE + +ST + + ++ T+ ++ S + +
Sbjct: 126 TNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETI 185
Query: 722 LPLT--SETSSVSSMLLTSETTFVSSLPLPSETSPISNSSINERMAHQQRKSPS-VSEEP 778
P T SET++VS+ SETT VS+ SET+ S AH + + S + E
Sbjct: 186 TPSTAGSETTTVSTA--GSETTTVSTTG--SETTTAST-------AHSETTAASTMGSET 234
Query: 779 LSPQKDESSATAKPLGENLTSQQKNLSNTPEPIIMSSSSIAPEAFPSEDLHNKTLSQQTC 838
S T G T+ S T +ED T S
Sbjct: 235 TKVSTAGSETTVSTAGSETTAASTEDSETNTAF-------------TEDSKTTTASTTGF 281
Query: 839 KSHVDTEKPYPASIPELASTEMIKVKNHSVLQRTEKKVLPSPLELS-VFSEGTDNKGNEL 897
++ T S P +AST + S + KV + E++ VF+ G++
Sbjct: 282 ET---TAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRAST 338
Query: 898 PSAKLQDKQYISSVDKAPFSEGSRNKTHKQGSTQSRLETSHTSKSSEPSKSPDGIRNESR 957
++ S GS T +T S T+ T S + S +G +
Sbjct: 339 VGSETTTVSTTGSETTTASIMGSETST--DSTTGSETTTASTEGSETTTASTEGSEATTV 396
Query: 958 DSEISKRKTAEQHSFGICKEKRARIEDDQSTRNISSSSPPEKEQPPREEPRVPPLKIQLS 1017
+ S+ T I D ++T + S +++
Sbjct: 397 STTGSETTTVS-------------ITDSETTTTCTEGS-------------------EMT 424
Query: 1018 KIGPPFIIKSQPVSKPESRASTSTSVSGGRNTGARTLADIKARAQQARAQREAAAAAAVA 1077
+ + + E T S S T A T + + A +
Sbjct: 425 AVSTT--VFETTTASTEGSEITIASTSDSETTTAST--------EGSETTTVTTAGSETK 474
Query: 1078 AAASIVSGAMGSPGEGGKTRTLAHIKEQTKAKLFAKHQARAHLFQTSKETRLPPPLSSKE 1137
A + S + G +T T+ I T + A S+ T + S E
Sbjct: 475 TAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTV-----STE 529
Query: 1138 GPPNLEVSST-PETKMEGSTGVIIVNPNCRSPSNKSAHLRETTTVLQQSLNPSKLPETAT 1196
G N VS+T ET +TG+ ETTT + + + T
Sbjct: 530 GSENTTVSTTGSETTTVSTTGL------------------ETTTTSTEGSEMTTVSTTGA 571
Query: 1197 DLSVHSSDENIPVSHLSEKIVSSTSSENSSVPMLFNKNSVPVSVCSTAISGAIKEHPFVS 1256
+ + S++ + S+ SE ++V ++N T S A E S
Sbjct: 572 ETTTDSTEGS------GTTAASTAGSETTTVSTADSEN--------TTASTADSETTSAS 617
Query: 1257 SVDKSSVLMSVDSANTTISACNISMLKTIQGTDTPCIAIIPKCIESTPISATTEGSSISS 1316
+ + S S+ TT ++ S T+ TD+ E+T +S T +I+S
Sbjct: 618 TTGSETTTASTTSSETTTASTEGSETTTVSTTDS----------ETTMVSTTGSERTITS 667
Query: 1317 SMDDKQLLISSSSASNLVSTQYTSVPTPSI-----------GNNLPNLSTSSVLIPPMGI 1365
+ + +S++ + VST+ + T SI G+ ST I I
Sbjct: 668 TEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASI 727
Query: 1366 NNRFPSEKIAIPGSEEQATVSMGTTVRAALSCSDSVAVTDSLVAHPTVAMFTGNMLTINS 1425
+ + GSE + G+ +A + + + T+A G+ T+ S
Sbjct: 728 TGS-ETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMAS 786
Query: 1426 ---YDSPPKLSAESLDKNSGPRNRADNSGKPQQPPGGFAPAAINRSIPCKVIVDHSTTLT 1482
++ +A S N A + +IP +TT T
Sbjct: 787 TIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTT 846
Query: 1483 SSLSLTVSVESSEASLDLQGRPVRTEASVQPVACPQVSVISRPEPVANEGIDHSSTFIAA 1542
S+ + S+E S + TE+S A ++ S + EG + ++T
Sbjct: 847 STEGSETTTASTEGS---ETTTASTESSETTTA---TTIGSETTTASTEGSETTTTSTEG 900
Query: 1543 S---AAKQDSKTLPATCTSLRELPLVPDKLNEPTAPSHNFAE 1581
S A + + T+ E + +E T S +E
Sbjct: 901 SETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSE 942
Score = 49.3 bits (116), Expect = 4e-05
Identities = 144/771 (18%), Positives = 258/771 (33%), Gaps = 98/771 (12%)
Query: 1039 TSTSVSGGRNTGARTLADIKARAQQARAQREAAAAAAVAAAASIVS------GAMGS--- 1089
T+TS +G NT + A A ++ + A + SI AMGS
Sbjct: 66 TTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETT 125
Query: 1090 ------------PGEGGKTRTLAHIKEQTKAKLFAKHQARAHLFQTSKETRLPPPLSSKE 1137
G +T T++ + +T A + A T E S+
Sbjct: 126 TNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTA-ASTTGSEMTTVFTAGSET 184
Query: 1138 GPPNLEVSSTPETKMEGSTGVIIVNPNCRSPSNKSAHLRETTTVLQQSLNPSKLPETATD 1197
P+ S T GS + + + +AH ETT +K+ ++
Sbjct: 185 ITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAH-SETTAASTMGSETTKVSTAGSE 243
Query: 1198 LSVHSSDENIPVSHLSEKIVSSTSSENSSVPMLFNKNSVPVSVC-----STAISGAIKEH 1252
+V ++ ++ S+E+S F ++S + +TA S E
Sbjct: 244 TTVSTAGSE----------TTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEP 293
Query: 1253 PFVSSVDKSSVLMSVDSANTTISACNISMLKTIQGTDTPCIAIIPKCIESTPISATTEGS 1312
S++ + + S TT + S + T+ + I E+T +S T +
Sbjct: 294 TMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSET 353
Query: 1313 SISSSMDDKQLLISSS-SASNLVSTQYTSVPTPSI-GNNLPNLSTSSVLIPPMGINNRFP 1370
+ +S M + S++ S + ST+ + T S G+ +ST+
Sbjct: 354 TTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTG-----------SE 402
Query: 1371 SEKIAIPGSEEQATVSMGTTVRAALSCSDSVAVTDSLVAHPTVAMFTGNMLTINSYDSPP 1430
+ ++I SE T + G+ + A + V T A G+ +TI S
Sbjct: 403 TTTVSITDSETTTTCTEGSEMTA----------VSTTVFETTTASTEGSEITIASTSDSE 452
Query: 1431 KLSAESLDKNSGPRNRADNSGKPQQPPGGFAPAAINRSIPCKVI--VDHSTT-------- 1480
+A + + A + K G A N + + + TT
Sbjct: 453 TTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSE 512
Query: 1481 -----LTSSLSLTVSVESSE-ASLDLQGRPVRT------EASVQPVACPQVSVISRPEPV 1528
T S TVS E SE ++ G T E + +++ +S
Sbjct: 513 TTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAE 572
Query: 1529 ANEGIDHSSTFIAASAAKQDSKTLPATCTSLRELPLVPDKLNEPTAPSHNFAEQARGPAP 1588
S AAS A ++ T+ +T S D +E T+ S +E A
Sbjct: 573 TTTDSTEGSGTTAASTAGSETTTV-STADSENTTASTAD--SETTSASTTGSETT--TAS 627
Query: 1589 FKSEADTTCSNQYNPSNRICWNDDG---MRSTG-QPLVTHSGSSKQKEYLEQSCPKAIKT 1644
S TT S + + + + D + +TG + +T + S+ + T
Sbjct: 628 TTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVST 687
Query: 1645 EHANYLNVSELHPRNLVTNVALPVKSELHEADKGFRMDTEDFPGPELPPPAAEGA----S 1700
E + VS T V+ + +G + T G E + EG+ +
Sbjct: 688 EGSGTTTVSITGSE--TTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTA 745
Query: 1701 SVQQTQNMKASTSSPMEEAISLATDALKRVPGAGSSGCRLSSVEANNPLVT 1751
S + ++ AST+ S + GS S++ + V+
Sbjct: 746 STEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVS 796
Score = 43.5 bits (101), Expect = 0.002
Identities = 93/473 (19%), Positives = 165/473 (34%), Gaps = 39/473 (8%)
Query: 373 TTGPNNAGAQSSSSCGTSGLPVSAQTALAEQQPKSMKSPASPEPGFCATLCPMVEIPPKD 432
TT + G++++S+ T +A T +E S+ G T+ +
Sbjct: 742 TTTASTEGSETTSASTTGSETTTASTTSSETTMASIM-------GSETTMASTIGSETTK 794
Query: 433 IMAELESEDILIPEESVIQEEIAEEVETSICECQDENHKTIPEFSEEAESLTNSHEEPQ- 491
+ + E S + IA + +TIP + +E+ T + E
Sbjct: 795 VSTASSKMTTVFTENS--ETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSE 852
Query: 492 -IAPPEDNLESCVMMNDVLETLPHIEVKIEGKSESPQEEMTVVIDQLEVCDSLIPSTSSM 550
+ E+ + ET + E + S + T + S
Sbjct: 853 TTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTS----------TEGSE 902
Query: 551 THVSDTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMEL---QSDPEEQLSENAC 607
T + TE E T ST +T ++S EG EL + E ++ +A
Sbjct: 903 TTTASTEGSEITTV---STTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAE 959
Query: 608 ISETSFSSESPEGACTSLPSPGGE---TQSTSEESCTPASLETTFCSEVSSTENTDKYNQ 664
SET+ + + G+ T+ S G T ST+ T AS+E + + VSST +
Sbjct: 960 GSETT--TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVS 1017
Query: 665 RNSTDENFHASLMSEISPISTSPEISEASLMSNLPLTSEASPVSNLPLTSETSPMSDLPL 724
T+ ++ SE + ++T+ + A + T+ ++ S S T +
Sbjct: 1018 TTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTAS 1077
Query: 725 TSETSSVSSMLLTSETTFVSSLPLPSETSPISNSSINERMAHQQRKSPSVSEEPLSPQKD 784
T++ + + S TT S+ + T I+ S S SE
Sbjct: 1078 TADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTT-------TASTEGSEATTVSTTS 1130
Query: 785 ESSATAKPLGENLTSQQKNLSNTPEPIIMSSSSIAPEAFPSEDLHNKTLSQQT 837
+ TA G +T+ +S T + S + A SE T +T
Sbjct: 1131 SETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSET 1183
Score = 40.8 bits (94), Expect = 0.015
Identities = 71/320 (22%), Positives = 121/320 (37%), Gaps = 36/320 (11%)
Query: 1269 SANTTISACNISMLKTIQGTDTPCIAIIPKCIESTPISATTEGSSISS-SMDDKQLLISS 1327
S+ TT++ S T T + I+ K E+T +A+T GS ++ S Q I S
Sbjct: 2 SSETTVAPAAGSNTTTASTTGSETTTILIKASETT--TASTAGSETTTPSPTGSQTTIVS 59
Query: 1328 SSASNLVST-----QYTSVPTPSIGNNLPNLSTSSVLIPPMGINNRFPSEKIAIPGSEEQ 1382
S S + +T + T+V + G +++ S + G + ++I G+E
Sbjct: 60 ISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSE----TTTVSITGTETT 115
Query: 1383 ATVSMGTTVRAALSCSDSVAVTDSLVAHPTVAMFTGNMLTINSYDSPPKLSAESLDKNSG 1442
+MG+ + S VT + + T G+ T +Y + + +A
Sbjct: 116 MVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSE-TTTAYTADSETTA-------- 166
Query: 1443 PRNRADNSGKPQQPPGGFAPAAINRSIPCKVIVDHSTTLTS--SLSLTVSVESSEASLDL 1500
A +G A + +I +TT+++ S + TVS SE +
Sbjct: 167 ----ASTTGSEMTT----VFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTAS 218
Query: 1501 QGRPVRTEASVQPVACPQVSVISRPEPVANEGIDHSSTFIAAS----AAKQDSKTLPATC 1556
T AS +VS V+ G + ++ S A +DSKT A+
Sbjct: 219 TAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTAST 278
Query: 1557 TSLRELPLVPDKLNEPTAPS 1576
T E +EPT S
Sbjct: 279 TGF-ETTAASTTGSEPTMAS 297
Score = 40.4 bits (93), Expect = 0.020
Identities = 75/341 (21%), Positives = 131/341 (38%), Gaps = 39/341 (11%)
Query: 459 ETSICECQDENHKTIPEFSEEAESLTNSHEEPQIAPPEDNLESCVMMNDVLETLPHIEVK 518
ET+I + T+ E ++ + E E + E+ + ET
Sbjct: 1022 ETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGS-ETTTVSTTGSETTTASTAD 1080
Query: 519 IEGKSESPQEEMTVVIDQLEVCDSLIPSTSSMTHVSDTEHKESETAVETSTPKIKTGSSS 578
+E + S T + + T S T + TE E+ T TS+ +T ++S
Sbjct: 1081 LETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSS---ETTTAS 1137
Query: 579 LEGQFPNEGIAIDMELQSDPEEQLSENACISETSFSSESPEGACTSLPSPGGETQSTSEE 638
G E + +SET+ S A TS + G E +TS E
Sbjct: 1138 TTGS-----------------EMTTVFTTVSETTTVSTIGSEATTS-SAAGSEATTTSTE 1179
Query: 639 -----SCTPASLETTFCSEVSSTENTDKYNQRNSTDENFHASLMSEIS-PISTSPEISEA 692
+ + A ETT S S T + ++ N + SE S P S E + A
Sbjct: 1180 GSETTTASTAGSETTTASTAGSETTTAS---TSGSETNTACTTGSETSTPSSAGSETNTA 1236
Query: 693 SLMSN---LPLTSEASPVSNLPLTSETSPMSDLPLTSETSSVSSMLLTSETTFVSSLPLP 749
++ + + T+ P + SET+ +S +T+ ++ +S + S TTFV +
Sbjct: 1237 FIIGSETTIASTASLEPTATSLTGSETTTVS---ITASGATAASTTV-SSTTFVLTKATD 1292
Query: 750 SETSPISNSSINERMAHQQRKSPSVSEEPLSPQKDESSATA 790
PI+N+ ++ R + S S ++P D +++ A
Sbjct: 1293 VSIQPITNTPMSGTRTTGTRLTAS-SSVTMAPGMDFTASAA 1332
>gi|239740898 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1542
Score = 69.3 bits (168), Expect = 4e-11
Identities = 204/1076 (18%), Positives = 372/1076 (34%), Gaps = 117/1076 (10%)
Query: 541 DSLIPSTSSMTHVSDTEHKESETA-------VETSTPKIKTGSSSLEGQFPNE----GIA 589
++ + + S T + TE E+ TA ST +T ++S G P G
Sbjct: 264 ETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSE 323
Query: 590 IDMELQSDPEEQLSENACISETSFSSESPEGACTSLPSPGGETQSTSEESCTPASL---E 646
M PE A T+ + E S T ST+ T AS+ E
Sbjct: 324 TTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSE 383
Query: 647 TTFCSEVSS---TENTDKYNQRNSTDENFHASLMSEISPISTSPEISEASLMSNLPLTSE 703
T+ S S T +T+ ++ E A+ +S +T+ I+++ + SE
Sbjct: 384 TSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSE 443
Query: 704 ASPVSN--LPLTSETSPMSDLPLTSETSSVSSMLLT--SETTFVSSL--------PLPSE 751
+ VS T+ ++ S++ + S + S ++ T SETT V++ SE
Sbjct: 444 MTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSE 503
Query: 752 TSPISNSSINERMAHQQRKSPSVSEEPLSPQKDESSATAKPLGENLTSQQKNLSNT---- 807
T+ SN+ + + + S + E++A + E T + NT
Sbjct: 504 TTTASNTGLETTTVFTIGSDTTTA----STEGSETTAVSATGSEMTTVSTEGSENTTVST 559
Query: 808 --PEPIIMSSSSIAPEAFPSEDLHNKTLSQQTCKSHVDTEKPYPASIPELASTEMIKV-- 863
E +S++ + +E T+S ++ D+ + + A +E V
Sbjct: 560 TGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVST 619
Query: 864 ---KNHSVLQRTEKKVLPSPLELSVFSEGTDNKGNELPSAKLQDKQYISSVDKAPFSEGS 920
+N + + S + T + S + + +S+ D +
Sbjct: 620 ADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVST 679
Query: 921 RNKTHKQGSTQSRLETSHTSKSSEPSKSPDGIRNESRDSEISKRKTAEQHSFGICKEKRA 980
ST+ T+ ++ SE + S +G + + I+ +T + + G +
Sbjct: 680 TGSERTITSTEGSETTTVSATGSETTVSTEG--SGTTTVSITGSETTKVSTTGSETTTTS 737
Query: 981 RIEDDQSTRNISSSSPPEKEQPPREEPRVPPLKIQLSKIGPPFIIKSQ-PVSKPESRAST 1039
+ +T +I+ S E E + S+ S+ + S +T
Sbjct: 738 TEGSEITTASITGS---ETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETT 794
Query: 1040 STSVSGGRNTGARTLADIKARAQQARAQ--------REAAAAAAVAAAASIVSGA----- 1086
S+ G T A T+ + A ++ E A+ A+ + VS A
Sbjct: 795 MASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETI 854
Query: 1087 -MGSPGEGGKTRTLAHIKEQTKAKLFAKHQARAHLFQTSKETRLPPPLSSKEGPPNLEVS 1145
+ G T T E T A A S ET + S+ + E S
Sbjct: 855 PASTAGSETTTTTSTEGSETTTASTEGSETTTAS--TESSETTTATTIGSETTTASTEGS 912
Query: 1146 STPETKMEGSTGVIIVNPNCRSPSNKSAHLRETTTVLQQSLNPSKLPETATDLSVHSSDE 1205
T T EGS + S + + + +T ++ S T S S+
Sbjct: 913 ETTTTSTEGS--------ETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSEL 964
Query: 1206 NIPVSHLSEKI-VSSTSSENSSVPMLFNKNSVPVSVCSTAISGAIKEHPFVSSVDKSSVL 1264
+ SE I VS+ SE ++V + ++ +T S A E VS+ +
Sbjct: 965 TTVSTTGSETITVSAEGSETTTVTTMGSE--------TTTASTAGSETTTVSTAGSETTT 1016
Query: 1265 MSVDSANTTISACNISMLKTIQGTDTPCIAIIPKCIESTPI-SATTEGSSISSSMDDKQL 1323
S++ + TT + S T+ T T + E+T + +A +E +++ ++ +
Sbjct: 1017 ASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTT 1076
Query: 1324 LISSSSASNLVSTQYTSVPTPSIGNNLPNLSTSSVLIPPMGINNRFPSEKIAIPGSEEQA 1383
+ S + VST + T S +L T++V G + + GSE
Sbjct: 1077 TSTEGSETTTVSTTGSETTTASTA----DLETTTVSTSGSG------TTTASTAGSETTT 1126
Query: 1384 TVSMGTTVRAALSCSDSVAVTDSLVAHPTVAMFTGNMLTINSYDSPPKLSAESLDKNSGP 1443
G+ A + + + T A TG+ +T + ++ +
Sbjct: 1127 VYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATT 1186
Query: 1444 RNRADNSGKPQQPPGGFAPAAINRSIPCKVIVDHSTTLTSSLSLTVSVESSEASLDLQGR 1503
+ A + G A S T T+S T E++ AS
Sbjct: 1187 SSAAGSEATTTSTEGSETTTASTAG---------SETTTAS---TAGSETTTAS------ 1228
Query: 1504 PVRTEASVQPVACPQVSVISRPEPVANEGIDHSSTFIAASAAKQDSKTLPATCTSL 1559
T S AC S S P +E +++ I + + +L T TSL
Sbjct: 1229 ---TSGSETNTACTTGSETSTPSSAGSE--TNTAFIIGSETTIASTASLEPTATSL 1279
Score = 69.3 bits (168), Expect = 4e-11
Identities = 177/921 (19%), Positives = 327/921 (35%), Gaps = 110/921 (11%)
Query: 547 TSSMTHVSDTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMELQSDPEEQLSENA 606
T S T + TE E TAV T+ + T S+ EG I + SD E
Sbjct: 430 TDSETTTTCTEGSEM-TAVSTTVFETTTAST--------EGSEITIASTSDSET------ 474
Query: 607 CISETSFSSESPEGACTSLPSPGGETQS---TSEESCTPAS--LETTFCSEVSSTENTDK 661
T+ S+E E T++ + G ET++ T E+ T ++ LETT + S T
Sbjct: 475 ----TTASTEGSE--TTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTAS 528
Query: 662 YNQRNSTDENFHASLMSEISP-------ISTSPEISEASLMSNLPLTSEASPVSNLPLTS 714
+T + S M+ +S +ST+ + + L T+ ++ S + S
Sbjct: 529 TEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVS 588
Query: 715 ETSPMSDLPLTSETSSVSSMLLTSETTFVSSLPLPSETSPISNSSINERMAHQQRKSPSV 774
T + T + + ++ SETT VS+ + T+ ++S S +
Sbjct: 589 TTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSA-------STTG 641
Query: 775 SEEPLSPQKDESSATAKPLGENLTSQQKNLSNTPEPIIMSSSSIAPEAFPS-EDLHNKTL 833
SE + + TA G T+ +S T M S++ + S E T+
Sbjct: 642 SETTTASTTSSETTTASTEGSETTT----VSTTDSETTMVSTTGSERTITSTEGSETTTV 697
Query: 834 SQQTCKSHVDTEKPYPASIPELASTEMIKVK---NHSVLQRTEKKVLPSPLELSVFSEGT 890
S ++ V TE ++ + +E KV + + TE + + +
Sbjct: 698 SATGSETTVSTEGSGTTTV-SITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTA 756
Query: 891 DNKGNELPSAKLQDKQYISSVDKAPFSEGSRNKTHKQGSTQSRLET-------------S 937
+G+E +A + + S+ + GS T S+++ + + S
Sbjct: 757 STEGSETTTASTEGSETTSAS-----TTGSETTTASTTSSETTMASIMGSETTMASTIGS 811
Query: 938 HTSKSSEPSKSPDGIRNESRDSEISKRKTAEQHSFGICKEKRARIEDDQS-TRNISSSSP 996
T+K S S + E+ ++ I+ +E + + S T +S+
Sbjct: 812 ETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEG 871
Query: 997 PEKEQPPREEPRVPPLKIQLSKIGPPFIIKSQPVS-KPESRASTSTSVSGGRNTGART-- 1053
E E + S+ I S+ + E +T+TS G T A T
Sbjct: 872 SETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEG 931
Query: 1054 -----LADIKARAQQARAQREAAAAAAVAAAASIVSGAMGSP-----GEGGKTRTLAHIK 1103
++ + A + A+ + GS EG +T T+ +
Sbjct: 932 SEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMG 991
Query: 1104 EQTKAKLFAKHQARAHLFQTSKETRLPPPLSSKEGPPNLEVSST-PETKMEGSTGVIIVN 1162
+T A + S+ T +S EG VSST ET +TG
Sbjct: 992 SETTTASTAGSETTTVSTAGSETTT-----ASIEGSETTTVSSTGSETTTVSTTGT---- 1042
Query: 1163 PNCRSPSNKSAHLRETTTVLQQSLNPSKLPETATDLSVHSSDENIPVSHLSEKIVSSTSS 1222
+ S ETTTV + + T ++ + S++ + + VS+T S
Sbjct: 1043 ----ETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTT------VSTTGS 1092
Query: 1223 ENSSVPMLFNKNSVPVSVCSTAISGAIKEHPFVSSVDKSSVLMSVDSANTTISACNISML 1282
E ++ + + + ST+ SG S+ + + + + TT ++ S
Sbjct: 1093 ETTTA----STADLETTTVSTSGSGTTT----ASTAGSETTTVYITGSKTTTASTEGSEA 1144
Query: 1283 KTIQGTDTPCIAIIPKCIESTPISAT-TEGSSISSSMDDKQLLISSSSASNLVSTQYTSV 1341
T+ T + E T + T +E +++S+ + ++ S + ST+ +
Sbjct: 1145 TTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSET 1204
Query: 1342 PTPSIGNNLPNLSTSSVLIPPMGINNRFPSEKIAIPGSEEQATVSMGTTVRAALSCSDSV 1401
T S + ++++ + + GSE S G+ A
Sbjct: 1205 TTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSET 1264
Query: 1402 AVTDSLVAHPTVAMFTGNMLT 1422
+ + PT TG+ T
Sbjct: 1265 TIASTASLEPTATSLTGSETT 1285
Score = 63.9 bits (154), Expect = 2e-09
Identities = 203/1084 (18%), Positives = 365/1084 (33%), Gaps = 147/1084 (13%)
Query: 520 EGKSESPQEEMTVVIDQLEVCDSLIPSTSSMTHVSDTEHKESETAVETSTPKIKTGSSSL 579
E + S + + + ++ P+ S T + T E+ T + ++ ++
Sbjct: 5 EATTTSTADSKVITASSMSSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGS 64
Query: 580 EGQFPNEGIAIDMELQSDPEEQLSENACISETSFSSESPEGACTSLPSPGGETQSTSEES 639
E P+ + + E + + SE + S + G T+ + T ST+
Sbjct: 65 ETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSESTISTAGSE 124
Query: 640 CTPASLETTFCSEVSSTENTDKYNQRNSTDENFHASLMSEISPISTSPEISEASLMSNLP 699
T S+ T + VS+ + N S++ ++ SE + +ST + + ++
Sbjct: 125 TTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSE 184
Query: 700 LTSEASPVSNLPLTSETSPMSDLPLT--SETSSVSSMLLTSETTFVSSLPLPSETSPISN 757
T+ ++ S + + P T SET++VS+ SETT VS+ SET+ S
Sbjct: 185 TTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTA--GSETTTVSTTG--SETTTAST 240
Query: 758 SSINERMAHQQRKSPS-VSEEPLSPQKDESSATAKPLGENLTSQQKNLSNTPEPIIMSSS 816
AH + + S + E S T G T+ S T
Sbjct: 241 -------AHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAF----- 288
Query: 817 SIAPEAFPSEDLHNKTLSQQTCKSHVDTEKPYPASIPELASTEMIKVKNHSVLQRTEKKV 876
+ED T S ++ T S P +AST + S + KV
Sbjct: 289 --------TEDSKTTTASTTGFET---TAASTTGSEPTMASTMGSETTMASTIGPETTKV 337
Query: 877 LPSPLELS-VFSEGTDNKGNELPSAKLQDKQYISSVDKAPFSEGSRNKTHKQGSTQSRLE 935
+ E++ VF+ G++ ++ S GS T +T S
Sbjct: 338 STASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETST--DSTTGSETT 395
Query: 936 TSHTSKSSEPSKSPDGIRNESRDSEISKRKTAEQHSFGICKEKRARIEDDQSTRNISSSS 995
T+ T S + S +G + + S+ T I D ++T + S
Sbjct: 396 TASTEGSETTTASTEGSEATTVSTTGSETTTVS-------------ITDSETTTTCTEGS 442
Query: 996 PPEKEQPPREEPRVPPLKIQLSKIGPPFIIKSQPVSKPESRASTSTSVSGGRNTGARTLA 1055
+++ + + + E T S S T A T
Sbjct: 443 -------------------EMTAVSTT--VFETTTASTEGSEITIASTSDSETTTAST-- 479
Query: 1056 DIKARAQQARAQREAAAAAAVAAAASIVSGAMGSPGEGGKTRTLAHIKEQTKAKLFAKHQ 1115
+ + A + A + S + G +T T+ I T +
Sbjct: 480 ------EGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSE 533
Query: 1116 ARAHLFQTSKETRLPPPLSSKEGPPNLEVSST-PETKMEGSTGVIIVNPNCRSPSNKSAH 1174
A S+ T + S EG N VS+T ET +TG+
Sbjct: 534 TTAVSATGSEMTTV-----STEGSENTTVSTTGSETTTVSTTGL---------------- 572
Query: 1175 LRETTTVLQQSLNPSKLPETATDLSVHSSDENIPVSHLSEKIVSSTSSENSSVPMLFNKN 1234
ETTT + + + T + + S++ + S+ SE ++V ++N
Sbjct: 573 --ETTTTSTEGSEMTTVSTTGAETTTDSTEGS------GTTAASTAGSETTTVSTADSEN 624
Query: 1235 SVPVSVCSTAISGAIKEHPFVSSVDKSSVLMSVDSANTTISACNISMLKTIQGTDTPCIA 1294
T S A E S+ + S S+ TT ++ S T+ TD+
Sbjct: 625 --------TTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDS---- 672
Query: 1295 IIPKCIESTPISATTEGSSISSSMDDKQLLISSSSASNLVSTQYTSVPTPSI-------- 1346
E+T +S T +I+S+ + +S++ + VST+ + T SI
Sbjct: 673 ------ETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKV 726
Query: 1347 ---GNNLPNLSTSSVLIPPMGINNRFPSEKIAIPGSEEQATVSMGTTVRAALSCSDSVAV 1403
G+ ST I I + + GSE + G+ +A +
Sbjct: 727 STTGSETTTTSTEGSEITTASITGS-ETTTASTEGSETTTASTEGSETTSASTTGSETTT 785
Query: 1404 TDSLVAHPTVAMFTGNMLTINS---YDSPPKLSAESLDKNSGPRNRADNSGKPQQPPGGF 1460
+ + T+A G+ T+ S ++ +A S N
Sbjct: 786 ASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTT 845
Query: 1461 APAAINRSIPCKVIVDHSTTLTSSLSLTVSVESSEASLDLQGRPVRTEASVQPVACPQVS 1520
A + +IP +TT TS+ + S+E S + TE+S A +
Sbjct: 846 VSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGS---ETTTASTESSETTTA---TT 899
Query: 1521 VISRPEPVANEGIDHSSTFIAAS---AAKQDSKTLPATCTSLRELPLVPDKLNEPTAPSH 1577
+ S + EG + ++T S A + + T+ E + +E T S
Sbjct: 900 IGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAST 959
Query: 1578 NFAE 1581
+E
Sbjct: 960 EGSE 963
Score = 48.9 bits (115), Expect = 6e-05
Identities = 144/771 (18%), Positives = 258/771 (33%), Gaps = 98/771 (12%)
Query: 1039 TSTSVSGGRNTGARTLADIKARAQQARAQREAAAAAAVAAAASIVS------GAMGS--- 1089
T+TS +G NT + A A ++ + A + SI AMGS
Sbjct: 87 TTTSTAGSENTTVSSAGSGTTTASMAGSESTISTAGSETTTVSITGTETTMVSAMGSETT 146
Query: 1090 ------------PGEGGKTRTLAHIKEQTKAKLFAKHQARAHLFQTSKETRLPPPLSSKE 1137
G +T T++ + +T A + A T E S+
Sbjct: 147 TNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTA-ASTTGSEMTTVFTAGSET 205
Query: 1138 GPPNLEVSSTPETKMEGSTGVIIVNPNCRSPSNKSAHLRETTTVLQQSLNPSKLPETATD 1197
P+ S T GS + + + +AH ETT +K+ ++
Sbjct: 206 ITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAH-SETTAASTMGSETTKVSTAGSE 264
Query: 1198 LSVHSSDENIPVSHLSEKIVSSTSSENSSVPMLFNKNSVPVSVC-----STAISGAIKEH 1252
+V ++ ++ S+E+S F ++S + +TA S E
Sbjct: 265 TTVSTAGSE----------TTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEP 314
Query: 1253 PFVSSVDKSSVLMSVDSANTTISACNISMLKTIQGTDTPCIAIIPKCIESTPISATTEGS 1312
S++ + + S TT + S + T+ + I E+T +S T +
Sbjct: 315 TMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSET 374
Query: 1313 SISSSMDDKQLLISSS-SASNLVSTQYTSVPTPSI-GNNLPNLSTSSVLIPPMGINNRFP 1370
+ +S M + S++ S + ST+ + T S G+ +ST+
Sbjct: 375 TTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTG-----------SE 423
Query: 1371 SEKIAIPGSEEQATVSMGTTVRAALSCSDSVAVTDSLVAHPTVAMFTGNMLTINSYDSPP 1430
+ ++I SE T + G+ + A + V T A G+ +TI S
Sbjct: 424 TTTVSITDSETTTTCTEGSEMTA----------VSTTVFETTTASTEGSEITIASTSDSE 473
Query: 1431 KLSAESLDKNSGPRNRADNSGKPQQPPGGFAPAAINRSIPCKVI--VDHSTT-------- 1480
+A + + A + K G A N + + + TT
Sbjct: 474 TTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSE 533
Query: 1481 -----LTSSLSLTVSVESSE-ASLDLQGRPVRT------EASVQPVACPQVSVISRPEPV 1528
T S TVS E SE ++ G T E + +++ +S
Sbjct: 534 TTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAE 593
Query: 1529 ANEGIDHSSTFIAASAAKQDSKTLPATCTSLRELPLVPDKLNEPTAPSHNFAEQARGPAP 1588
S AAS A ++ T+ +T S D +E T+ S +E A
Sbjct: 594 TTTDSTEGSGTTAASTAGSETTTV-STADSENTTASTAD--SETTSASTTGSETT--TAS 648
Query: 1589 FKSEADTTCSNQYNPSNRICWNDDG---MRSTG-QPLVTHSGSSKQKEYLEQSCPKAIKT 1644
S TT S + + + + D + +TG + +T + S+ + T
Sbjct: 649 TTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVST 708
Query: 1645 EHANYLNVSELHPRNLVTNVALPVKSELHEADKGFRMDTEDFPGPELPPPAAEGA----S 1700
E + VS T V+ + +G + T G E + EG+ +
Sbjct: 709 EGSGTTTVSITGSE--TTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTA 766
Query: 1701 SVQQTQNMKASTSSPMEEAISLATDALKRVPGAGSSGCRLSSVEANNPLVT 1751
S + ++ AST+ S + GS S++ + V+
Sbjct: 767 STEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVS 817
Score = 43.5 bits (101), Expect = 0.002
Identities = 93/473 (19%), Positives = 165/473 (34%), Gaps = 39/473 (8%)
Query: 373 TTGPNNAGAQSSSSCGTSGLPVSAQTALAEQQPKSMKSPASPEPGFCATLCPMVEIPPKD 432
TT + G++++S+ T +A T +E S+ G T+ +
Sbjct: 763 TTTASTEGSETTSASTTGSETTTASTTSSETTMASIM-------GSETTMASTIGSETTK 815
Query: 433 IMAELESEDILIPEESVIQEEIAEEVETSICECQDENHKTIPEFSEEAESLTNSHEEPQ- 491
+ + E S + IA + +TIP + +E+ T + E
Sbjct: 816 VSTASSKMTTVFTENS--ETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSE 873
Query: 492 -IAPPEDNLESCVMMNDVLETLPHIEVKIEGKSESPQEEMTVVIDQLEVCDSLIPSTSSM 550
+ E+ + ET + E + S + T + S
Sbjct: 874 TTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTS----------TEGSE 923
Query: 551 THVSDTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMEL---QSDPEEQLSENAC 607
T + TE E T ST +T ++S EG EL + E ++ +A
Sbjct: 924 TTTASTEGSEITTV---STTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAE 980
Query: 608 ISETSFSSESPEGACTSLPSPGGE---TQSTSEESCTPASLETTFCSEVSSTENTDKYNQ 664
SET+ + + G+ T+ S G T ST+ T AS+E + + VSST +
Sbjct: 981 GSETT--TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVS 1038
Query: 665 RNSTDENFHASLMSEISPISTSPEISEASLMSNLPLTSEASPVSNLPLTSETSPMSDLPL 724
T+ ++ SE + ++T+ + A + T+ ++ S S T +
Sbjct: 1039 TTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTAS 1098
Query: 725 TSETSSVSSMLLTSETTFVSSLPLPSETSPISNSSINERMAHQQRKSPSVSEEPLSPQKD 784
T++ + + S TT S+ + T I+ S S SE
Sbjct: 1099 TADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTT-------TASTEGSEATTVSTTS 1151
Query: 785 ESSATAKPLGENLTSQQKNLSNTPEPIIMSSSSIAPEAFPSEDLHNKTLSQQT 837
+ TA G +T+ +S T + S + A SE T +T
Sbjct: 1152 SETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSET 1204
Score = 40.4 bits (93), Expect = 0.020
Identities = 75/341 (21%), Positives = 131/341 (38%), Gaps = 39/341 (11%)
Query: 459 ETSICECQDENHKTIPEFSEEAESLTNSHEEPQIAPPEDNLESCVMMNDVLETLPHIEVK 518
ET+I + T+ E ++ + E E + E+ + ET
Sbjct: 1043 ETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGS-ETTTVSTTGSETTTASTAD 1101
Query: 519 IEGKSESPQEEMTVVIDQLEVCDSLIPSTSSMTHVSDTEHKESETAVETSTPKIKTGSSS 578
+E + S T + + T S T + TE E+ T TS+ +T ++S
Sbjct: 1102 LETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSS---ETTTAS 1158
Query: 579 LEGQFPNEGIAIDMELQSDPEEQLSENACISETSFSSESPEGACTSLPSPGGETQSTSEE 638
G E + +SET+ S A TS + G E +TS E
Sbjct: 1159 TTGS-----------------EMTTVFTTVSETTTVSTIGSEATTS-SAAGSEATTTSTE 1200
Query: 639 -----SCTPASLETTFCSEVSSTENTDKYNQRNSTDENFHASLMSEIS-PISTSPEISEA 692
+ + A ETT S S T + ++ N + SE S P S E + A
Sbjct: 1201 GSETTTASTAGSETTTASTAGSETTTAS---TSGSETNTACTTGSETSTPSSAGSETNTA 1257
Query: 693 SLMSN---LPLTSEASPVSNLPLTSETSPMSDLPLTSETSSVSSMLLTSETTFVSSLPLP 749
++ + + T+ P + SET+ +S +T+ ++ +S + S TTFV +
Sbjct: 1258 FIIGSETTIASTASLEPTATSLTGSETTTVS---ITASGATAASTTV-SSTTFVLTKATD 1313
Query: 750 SETSPISNSSINERMAHQQRKSPSVSEEPLSPQKDESSATA 790
PI+N+ ++ R + S S ++P D +++ A
Sbjct: 1314 VSIQPITNTPMSGTRTTGTRLTAS-SSVTMAPGMDFTASAA 1353
>gi|239740777 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1612
Score = 69.3 bits (168), Expect = 4e-11
Identities = 204/1076 (18%), Positives = 372/1076 (34%), Gaps = 117/1076 (10%)
Query: 541 DSLIPSTSSMTHVSDTEHKESETA-------VETSTPKIKTGSSSLEGQFPNE----GIA 589
++ + + S T + TE E+ TA ST +T ++S G P G
Sbjct: 243 ETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSE 302
Query: 590 IDMELQSDPEEQLSENACISETSFSSESPEGACTSLPSPGGETQSTSEESCTPASL---E 646
M PE A T+ + E S T ST+ T AS+ E
Sbjct: 303 TTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSE 362
Query: 647 TTFCSEVSS---TENTDKYNQRNSTDENFHASLMSEISPISTSPEISEASLMSNLPLTSE 703
T+ S S T +T+ ++ E A+ +S +T+ I+++ + SE
Sbjct: 363 TSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSE 422
Query: 704 ASPVSN--LPLTSETSPMSDLPLTSETSSVSSMLLT--SETTFVSSL--------PLPSE 751
+ VS T+ ++ S++ + S + S ++ T SETT V++ SE
Sbjct: 423 MTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSE 482
Query: 752 TSPISNSSINERMAHQQRKSPSVSEEPLSPQKDESSATAKPLGENLTSQQKNLSNT---- 807
T+ SN+ + + + S + E++A + E T + NT
Sbjct: 483 TTTASNTGLETTTVFTIGSDTTTA----STEGSETTAVSATGSEMTTVSTEGSENTTVST 538
Query: 808 --PEPIIMSSSSIAPEAFPSEDLHNKTLSQQTCKSHVDTEKPYPASIPELASTEMIKV-- 863
E +S++ + +E T+S ++ D+ + + A +E V
Sbjct: 539 TGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVST 598
Query: 864 ---KNHSVLQRTEKKVLPSPLELSVFSEGTDNKGNELPSAKLQDKQYISSVDKAPFSEGS 920
+N + + S + T + S + + +S+ D +
Sbjct: 599 ADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVST 658
Query: 921 RNKTHKQGSTQSRLETSHTSKSSEPSKSPDGIRNESRDSEISKRKTAEQHSFGICKEKRA 980
ST+ T+ ++ SE + S +G + + I+ +T + + G +
Sbjct: 659 TGSERTITSTEGSETTTVSATGSETTVSTEG--SGTTTVSITGSETTKVSTTGSETTTTS 716
Query: 981 RIEDDQSTRNISSSSPPEKEQPPREEPRVPPLKIQLSKIGPPFIIKSQ-PVSKPESRAST 1039
+ +T +I+ S E E + S+ S+ + S +T
Sbjct: 717 TEGSEITTASITGS---ETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETT 773
Query: 1040 STSVSGGRNTGARTLADIKARAQQARAQ--------REAAAAAAVAAAASIVSGA----- 1086
S+ G T A T+ + A ++ E A+ A+ + VS A
Sbjct: 774 MASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETI 833
Query: 1087 -MGSPGEGGKTRTLAHIKEQTKAKLFAKHQARAHLFQTSKETRLPPPLSSKEGPPNLEVS 1145
+ G T T E T A A S ET + S+ + E S
Sbjct: 834 PASTAGSETTTTTSTEGSETTTASTEGSETTTAS--TESSETTTATTIGSETTTASTEGS 891
Query: 1146 STPETKMEGSTGVIIVNPNCRSPSNKSAHLRETTTVLQQSLNPSKLPETATDLSVHSSDE 1205
T T EGS + S + + + +T ++ S T S S+
Sbjct: 892 ETTTTSTEGS--------ETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSEL 943
Query: 1206 NIPVSHLSEKI-VSSTSSENSSVPMLFNKNSVPVSVCSTAISGAIKEHPFVSSVDKSSVL 1264
+ SE I VS+ SE ++V + ++ +T S A E VS+ +
Sbjct: 944 TTVSTTGSETITVSAEGSETTTVTTMGSE--------TTTASTAGSETTTVSTAGSETTT 995
Query: 1265 MSVDSANTTISACNISMLKTIQGTDTPCIAIIPKCIESTPI-SATTEGSSISSSMDDKQL 1323
S++ + TT + S T+ T T + E+T + +A +E +++ ++ +
Sbjct: 996 ASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTT 1055
Query: 1324 LISSSSASNLVSTQYTSVPTPSIGNNLPNLSTSSVLIPPMGINNRFPSEKIAIPGSEEQA 1383
+ S + VST + T S +L T++V G + + GSE
Sbjct: 1056 TSTEGSETTTVSTTGSETTTASTA----DLETTTVSTSGSG------TTTASTAGSETTT 1105
Query: 1384 TVSMGTTVRAALSCSDSVAVTDSLVAHPTVAMFTGNMLTINSYDSPPKLSAESLDKNSGP 1443
G+ A + + + T A TG+ +T + ++ +
Sbjct: 1106 VYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATT 1165
Query: 1444 RNRADNSGKPQQPPGGFAPAAINRSIPCKVIVDHSTTLTSSLSLTVSVESSEASLDLQGR 1503
+ A + G A S T T+S T E++ AS
Sbjct: 1166 SSAAGSEATTTSTEGSETTTASTAG---------SETTTAS---TAGSETTTAS------ 1207
Query: 1504 PVRTEASVQPVACPQVSVISRPEPVANEGIDHSSTFIAASAAKQDSKTLPATCTSL 1559
T S AC S S P +E +++ I + + +L T TSL
Sbjct: 1208 ---TSGSETNTACTTGSETSTPSSAGSE--TNTAFIIGSETTIASTASLEPTATSL 1258
Score = 69.3 bits (168), Expect = 4e-11
Identities = 177/921 (19%), Positives = 327/921 (35%), Gaps = 110/921 (11%)
Query: 547 TSSMTHVSDTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMELQSDPEEQLSENA 606
T S T + TE E TAV T+ + T S+ EG I + SD E
Sbjct: 409 TDSETTTTCTEGSEM-TAVSTTVFETTTAST--------EGSEITIASTSDSET------ 453
Query: 607 CISETSFSSESPEGACTSLPSPGGETQS---TSEESCTPAS--LETTFCSEVSSTENTDK 661
T+ S+E E T++ + G ET++ T E+ T ++ LETT + S T
Sbjct: 454 ----TTASTEGSE--TTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTAS 507
Query: 662 YNQRNSTDENFHASLMSEISP-------ISTSPEISEASLMSNLPLTSEASPVSNLPLTS 714
+T + S M+ +S +ST+ + + L T+ ++ S + S
Sbjct: 508 TEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVS 567
Query: 715 ETSPMSDLPLTSETSSVSSMLLTSETTFVSSLPLPSETSPISNSSINERMAHQQRKSPSV 774
T + T + + ++ SETT VS+ + T+ ++S S +
Sbjct: 568 TTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSA-------STTG 620
Query: 775 SEEPLSPQKDESSATAKPLGENLTSQQKNLSNTPEPIIMSSSSIAPEAFPS-EDLHNKTL 833
SE + + TA G T+ +S T M S++ + S E T+
Sbjct: 621 SETTTASTTSSETTTASTEGSETTT----VSTTDSETTMVSTTGSERTITSTEGSETTTV 676
Query: 834 SQQTCKSHVDTEKPYPASIPELASTEMIKVK---NHSVLQRTEKKVLPSPLELSVFSEGT 890
S ++ V TE ++ + +E KV + + TE + + +
Sbjct: 677 SATGSETTVSTEGSGTTTV-SITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTA 735
Query: 891 DNKGNELPSAKLQDKQYISSVDKAPFSEGSRNKTHKQGSTQSRLET-------------S 937
+G+E +A + + S+ + GS T S+++ + + S
Sbjct: 736 STEGSETTTASTEGSETTSAS-----TTGSETTTASTTSSETTMASIMGSETTMASTIGS 790
Query: 938 HTSKSSEPSKSPDGIRNESRDSEISKRKTAEQHSFGICKEKRARIEDDQS-TRNISSSSP 996
T+K S S + E+ ++ I+ +E + + S T +S+
Sbjct: 791 ETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEG 850
Query: 997 PEKEQPPREEPRVPPLKIQLSKIGPPFIIKSQPVS-KPESRASTSTSVSGGRNTGART-- 1053
E E + S+ I S+ + E +T+TS G T A T
Sbjct: 851 SETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEG 910
Query: 1054 -----LADIKARAQQARAQREAAAAAAVAAAASIVSGAMGSP-----GEGGKTRTLAHIK 1103
++ + A + A+ + GS EG +T T+ +
Sbjct: 911 SEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMG 970
Query: 1104 EQTKAKLFAKHQARAHLFQTSKETRLPPPLSSKEGPPNLEVSST-PETKMEGSTGVIIVN 1162
+T A + S+ T +S EG VSST ET +TG
Sbjct: 971 SETTTASTAGSETTTVSTAGSETTT-----ASIEGSETTTVSSTGSETTTVSTTGT---- 1021
Query: 1163 PNCRSPSNKSAHLRETTTVLQQSLNPSKLPETATDLSVHSSDENIPVSHLSEKIVSSTSS 1222
+ S ETTTV + + T ++ + S++ + + VS+T S
Sbjct: 1022 ----ETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTT------VSTTGS 1071
Query: 1223 ENSSVPMLFNKNSVPVSVCSTAISGAIKEHPFVSSVDKSSVLMSVDSANTTISACNISML 1282
E ++ + + + ST+ SG S+ + + + + TT ++ S
Sbjct: 1072 ETTTA----STADLETTTVSTSGSGTTT----ASTAGSETTTVYITGSKTTTASTEGSEA 1123
Query: 1283 KTIQGTDTPCIAIIPKCIESTPISAT-TEGSSISSSMDDKQLLISSSSASNLVSTQYTSV 1341
T+ T + E T + T +E +++S+ + ++ S + ST+ +
Sbjct: 1124 TTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSET 1183
Query: 1342 PTPSIGNNLPNLSTSSVLIPPMGINNRFPSEKIAIPGSEEQATVSMGTTVRAALSCSDSV 1401
T S + ++++ + + GSE S G+ A
Sbjct: 1184 TTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSET 1243
Query: 1402 AVTDSLVAHPTVAMFTGNMLT 1422
+ + PT TG+ T
Sbjct: 1244 TIASTASLEPTATSLTGSETT 1264
Score = 62.4 bits (150), Expect = 5e-09
Identities = 201/1062 (18%), Positives = 359/1062 (33%), Gaps = 147/1062 (13%)
Query: 542 SLIPSTSSMTHVSDTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMELQSDPEEQ 601
++ P+ S T + T E+ T + ++ ++ E P+ + + E
Sbjct: 6 TVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEI 65
Query: 602 LSENACISETSFSSESPEGACTSLPSPGGETQSTSEESCTPASLETTFCSEVSSTENTDK 661
+ + SE + S + G T+ + T ST+ T S+ T + VS+ +
Sbjct: 66 TTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETT 125
Query: 662 YNQRNSTDENFHASLMSEISPISTSPEISEASLMSNLPLTSEASPVSNLPLTSETSPMSD 721
N S++ ++ SE + +ST + + ++ T+ ++ S + +
Sbjct: 126 TNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETI 185
Query: 722 LPLT--SETSSVSSMLLTSETTFVSSLPLPSETSPISNSSINERMAHQQRKSPS-VSEEP 778
P T SET++VS+ SETT VS+ SET+ S AH + + S + E
Sbjct: 186 TPSTAGSETTTVSTA--GSETTTVSTTG--SETTTAST-------AHSETTAASTMGSET 234
Query: 779 LSPQKDESSATAKPLGENLTSQQKNLSNTPEPIIMSSSSIAPEAFPSEDLHNKTLSQQTC 838
S T G T+ S T +ED T S
Sbjct: 235 TKVSTAGSETTVSTAGSETTAASTEDSETNTAF-------------TEDSKTTTASTTGF 281
Query: 839 KSHVDTEKPYPASIPELASTEMIKVKNHSVLQRTEKKVLPSPLELS-VFSEGTDNKGNEL 897
++ T S P +AST + S + KV + E++ VF+ G++
Sbjct: 282 ET---TAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRAST 338
Query: 898 PSAKLQDKQYISSVDKAPFSEGSRNKTHKQGSTQSRLETSHTSKSSEPSKSPDGIRNESR 957
++ S GS T +T S T+ T S + S +G +
Sbjct: 339 VGSETTTVSTTGSETTTASIMGSETST--DSTTGSETTTASTEGSETTTASTEGSEATTV 396
Query: 958 DSEISKRKTAEQHSFGICKEKRARIEDDQSTRNISSSSPPEKEQPPREEPRVPPLKIQLS 1017
+ S+ T I D ++T + S +++
Sbjct: 397 STTGSETTTVS-------------ITDSETTTTCTEGS-------------------EMT 424
Query: 1018 KIGPPFIIKSQPVSKPESRASTSTSVSGGRNTGARTLADIKARAQQARAQREAAAAAAVA 1077
+ + + E T S S T A T + + A +
Sbjct: 425 AVSTT--VFETTTASTEGSEITIASTSDSETTTAST--------EGSETTTVTTAGSETK 474
Query: 1078 AAASIVSGAMGSPGEGGKTRTLAHIKEQTKAKLFAKHQARAHLFQTSKETRLPPPLSSKE 1137
A + S + G +T T+ I T + A S+ T + S E
Sbjct: 475 TAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTV-----STE 529
Query: 1138 GPPNLEVSST-PETKMEGSTGVIIVNPNCRSPSNKSAHLRETTTVLQQSLNPSKLPETAT 1196
G N VS+T ET +TG+ ETTT + + + T
Sbjct: 530 GSENTTVSTTGSETTTVSTTGL------------------ETTTTSTEGSEMTTVSTTGA 571
Query: 1197 DLSVHSSDENIPVSHLSEKIVSSTSSENSSVPMLFNKNSVPVSVCSTAISGAIKEHPFVS 1256
+ + S++ + S+ SE ++V ++N T S A E S
Sbjct: 572 ETTTDSTEGS------GTTAASTAGSETTTVSTADSEN--------TTASTADSETTSAS 617
Query: 1257 SVDKSSVLMSVDSANTTISACNISMLKTIQGTDTPCIAIIPKCIESTPISATTEGSSISS 1316
+ + S S+ TT ++ S T+ TD+ E+T +S T +I+S
Sbjct: 618 TTGSETTTASTTSSETTTASTEGSETTTVSTTDS----------ETTMVSTTGSERTITS 667
Query: 1317 SMDDKQLLISSSSASNLVSTQYTSVPTPSI-----------GNNLPNLSTSSVLIPPMGI 1365
+ + +S++ + VST+ + T SI G+ ST I I
Sbjct: 668 TEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASI 727
Query: 1366 NNRFPSEKIAIPGSEEQATVSMGTTVRAALSCSDSVAVTDSLVAHPTVAMFTGNMLTINS 1425
+ + GSE + G+ +A + + + T+A G+ T+ S
Sbjct: 728 TGS-ETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMAS 786
Query: 1426 ---YDSPPKLSAESLDKNSGPRNRADNSGKPQQPPGGFAPAAINRSIPCKVIVDHSTTLT 1482
++ +A S N A + +IP +TT T
Sbjct: 787 TIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTT 846
Query: 1483 SSLSLTVSVESSEASLDLQGRPVRTEASVQPVACPQVSVISRPEPVANEGIDHSSTFIAA 1542
S+ + S+E S + TE+S A ++ S + EG + ++T
Sbjct: 847 STEGSETTTASTEGS---ETTTASTESSETTTA---TTIGSETTTASTEGSETTTTSTEG 900
Query: 1543 S---AAKQDSKTLPATCTSLRELPLVPDKLNEPTAPSHNFAE 1581
S A + + T+ E + +E T S +E
Sbjct: 901 SETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSE 942
Score = 49.3 bits (116), Expect = 4e-05
Identities = 144/771 (18%), Positives = 258/771 (33%), Gaps = 98/771 (12%)
Query: 1039 TSTSVSGGRNTGARTLADIKARAQQARAQREAAAAAAVAAAASIVS------GAMGS--- 1089
T+TS +G NT + A A ++ + A + SI AMGS
Sbjct: 66 TTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETT 125
Query: 1090 ------------PGEGGKTRTLAHIKEQTKAKLFAKHQARAHLFQTSKETRLPPPLSSKE 1137
G +T T++ + +T A + A T E S+
Sbjct: 126 TNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTA-ASTTGSEMTTVFTAGSET 184
Query: 1138 GPPNLEVSSTPETKMEGSTGVIIVNPNCRSPSNKSAHLRETTTVLQQSLNPSKLPETATD 1197
P+ S T GS + + + +AH ETT +K+ ++
Sbjct: 185 ITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAH-SETTAASTMGSETTKVSTAGSE 243
Query: 1198 LSVHSSDENIPVSHLSEKIVSSTSSENSSVPMLFNKNSVPVSVC-----STAISGAIKEH 1252
+V ++ ++ S+E+S F ++S + +TA S E
Sbjct: 244 TTVSTAGSE----------TTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEP 293
Query: 1253 PFVSSVDKSSVLMSVDSANTTISACNISMLKTIQGTDTPCIAIIPKCIESTPISATTEGS 1312
S++ + + S TT + S + T+ + I E+T +S T +
Sbjct: 294 TMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSET 353
Query: 1313 SISSSMDDKQLLISSS-SASNLVSTQYTSVPTPSI-GNNLPNLSTSSVLIPPMGINNRFP 1370
+ +S M + S++ S + ST+ + T S G+ +ST+
Sbjct: 354 TTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTG-----------SE 402
Query: 1371 SEKIAIPGSEEQATVSMGTTVRAALSCSDSVAVTDSLVAHPTVAMFTGNMLTINSYDSPP 1430
+ ++I SE T + G+ + A + V T A G+ +TI S
Sbjct: 403 TTTVSITDSETTTTCTEGSEMTA----------VSTTVFETTTASTEGSEITIASTSDSE 452
Query: 1431 KLSAESLDKNSGPRNRADNSGKPQQPPGGFAPAAINRSIPCKVI--VDHSTT-------- 1480
+A + + A + K G A N + + + TT
Sbjct: 453 TTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSE 512
Query: 1481 -----LTSSLSLTVSVESSE-ASLDLQGRPVRT------EASVQPVACPQVSVISRPEPV 1528
T S TVS E SE ++ G T E + +++ +S
Sbjct: 513 TTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAE 572
Query: 1529 ANEGIDHSSTFIAASAAKQDSKTLPATCTSLRELPLVPDKLNEPTAPSHNFAEQARGPAP 1588
S AAS A ++ T+ +T S D +E T+ S +E A
Sbjct: 573 TTTDSTEGSGTTAASTAGSETTTV-STADSENTTASTAD--SETTSASTTGSETT--TAS 627
Query: 1589 FKSEADTTCSNQYNPSNRICWNDDG---MRSTG-QPLVTHSGSSKQKEYLEQSCPKAIKT 1644
S TT S + + + + D + +TG + +T + S+ + T
Sbjct: 628 TTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVST 687
Query: 1645 EHANYLNVSELHPRNLVTNVALPVKSELHEADKGFRMDTEDFPGPELPPPAAEGA----S 1700
E + VS T V+ + +G + T G E + EG+ +
Sbjct: 688 EGSGTTTVSITGSE--TTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTA 745
Query: 1701 SVQQTQNMKASTSSPMEEAISLATDALKRVPGAGSSGCRLSSVEANNPLVT 1751
S + ++ AST+ S + GS S++ + V+
Sbjct: 746 STEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVS 796
Score = 43.5 bits (101), Expect = 0.002
Identities = 93/473 (19%), Positives = 165/473 (34%), Gaps = 39/473 (8%)
Query: 373 TTGPNNAGAQSSSSCGTSGLPVSAQTALAEQQPKSMKSPASPEPGFCATLCPMVEIPPKD 432
TT + G++++S+ T +A T +E S+ G T+ +
Sbjct: 742 TTTASTEGSETTSASTTGSETTTASTTSSETTMASIM-------GSETTMASTIGSETTK 794
Query: 433 IMAELESEDILIPEESVIQEEIAEEVETSICECQDENHKTIPEFSEEAESLTNSHEEPQ- 491
+ + E S + IA + +TIP + +E+ T + E
Sbjct: 795 VSTASSKMTTVFTENS--ETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSE 852
Query: 492 -IAPPEDNLESCVMMNDVLETLPHIEVKIEGKSESPQEEMTVVIDQLEVCDSLIPSTSSM 550
+ E+ + ET + E + S + T + S
Sbjct: 853 TTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTS----------TEGSE 902
Query: 551 THVSDTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMEL---QSDPEEQLSENAC 607
T + TE E T ST +T ++S EG EL + E ++ +A
Sbjct: 903 TTTASTEGSEITTV---STTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAE 959
Query: 608 ISETSFSSESPEGACTSLPSPGGE---TQSTSEESCTPASLETTFCSEVSSTENTDKYNQ 664
SET+ + + G+ T+ S G T ST+ T AS+E + + VSST +
Sbjct: 960 GSETT--TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVS 1017
Query: 665 RNSTDENFHASLMSEISPISTSPEISEASLMSNLPLTSEASPVSNLPLTSETSPMSDLPL 724
T+ ++ SE + ++T+ + A + T+ ++ S S T +
Sbjct: 1018 TTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTAS 1077
Query: 725 TSETSSVSSMLLTSETTFVSSLPLPSETSPISNSSINERMAHQQRKSPSVSEEPLSPQKD 784
T++ + + S TT S+ + T I+ S S SE
Sbjct: 1078 TADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTT-------TASTEGSEATTVSTTS 1130
Query: 785 ESSATAKPLGENLTSQQKNLSNTPEPIIMSSSSIAPEAFPSEDLHNKTLSQQT 837
+ TA G +T+ +S T + S + A SE T +T
Sbjct: 1131 SETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSET 1183
Score = 40.8 bits (94), Expect = 0.015
Identities = 71/320 (22%), Positives = 121/320 (37%), Gaps = 36/320 (11%)
Query: 1269 SANTTISACNISMLKTIQGTDTPCIAIIPKCIESTPISATTEGSSISS-SMDDKQLLISS 1327
S+ TT++ S T T + I+ K E+T +A+T GS ++ S Q I S
Sbjct: 2 SSETTVAPAAGSNTTTASTTGSETTTILIKASETT--TASTAGSETTTPSPTGSQTTIVS 59
Query: 1328 SSASNLVST-----QYTSVPTPSIGNNLPNLSTSSVLIPPMGINNRFPSEKIAIPGSEEQ 1382
S S + +T + T+V + G +++ S + G + ++I G+E
Sbjct: 60 ISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSE----TTTVSITGTETT 115
Query: 1383 ATVSMGTTVRAALSCSDSVAVTDSLVAHPTVAMFTGNMLTINSYDSPPKLSAESLDKNSG 1442
+MG+ + S VT + + T G+ T +Y + + +A
Sbjct: 116 MVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSE-TTTAYTADSETTA-------- 166
Query: 1443 PRNRADNSGKPQQPPGGFAPAAINRSIPCKVIVDHSTTLTS--SLSLTVSVESSEASLDL 1500
A +G A + +I +TT+++ S + TVS SE +
Sbjct: 167 ----ASTTGSEMTT----VFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTAS 218
Query: 1501 QGRPVRTEASVQPVACPQVSVISRPEPVANEGIDHSSTFIAAS----AAKQDSKTLPATC 1556
T AS +VS V+ G + ++ S A +DSKT A+
Sbjct: 219 TAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTAST 278
Query: 1557 TSLRELPLVPDKLNEPTAPS 1576
T E +EPT S
Sbjct: 279 TGF-ETTAASTTGSEPTMAS 297
Score = 40.8 bits (94), Expect = 0.015
Identities = 75/341 (21%), Positives = 131/341 (38%), Gaps = 39/341 (11%)
Query: 459 ETSICECQDENHKTIPEFSEEAESLTNSHEEPQIAPPEDNLESCVMMNDVLETLPHIEVK 518
ET+I + T+ E ++ + E E + E+ + ET
Sbjct: 1022 ETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGS-ETTTVSTTGSETTTASTAD 1080
Query: 519 IEGKSESPQEEMTVVIDQLEVCDSLIPSTSSMTHVSDTEHKESETAVETSTPKIKTGSSS 578
+E + S T + + T S T + TE E+ T TS+ +T ++S
Sbjct: 1081 LETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSS---ETTTAS 1137
Query: 579 LEGQFPNEGIAIDMELQSDPEEQLSENACISETSFSSESPEGACTSLPSPGGETQSTSEE 638
G E + +SET+ S A TS + G E +TS E
Sbjct: 1138 TTGS-----------------EMTTVFTTVSETTTVSTIGSEATTS-SAAGSEATTTSTE 1179
Query: 639 -----SCTPASLETTFCSEVSSTENTDKYNQRNSTDENFHASLMSEIS-PISTSPEISEA 692
+ + A ETT S S T + ++ N + SE S P S E + A
Sbjct: 1180 GSETTTASTAGSETTTASTAGSETTTAS---TSGSETNTACTTGSETSTPSSAGSETNTA 1236
Query: 693 SLMSN---LPLTSEASPVSNLPLTSETSPMSDLPLTSETSSVSSMLLTSETTFVSSLPLP 749
++ + + T+ P + SET+ +S +T+ ++ +S + S TTFV +
Sbjct: 1237 FIIGSETTIASTASLEPTATSLTGSETTTVS---ITASGATAASTTV-SSTTFVLTKATD 1292
Query: 750 SETSPISNSSINERMAHQQRKSPSVSEEPLSPQKDESSATA 790
PI+N+ ++ R + S S ++P D +++ A
Sbjct: 1293 VSIQPITNTPMSGTRTTGTRPTAS-SSVTMAPGMDFTASAA 1332
>gi|239740724 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1704
Score = 69.3 bits (168), Expect = 4e-11
Identities = 204/1076 (18%), Positives = 372/1076 (34%), Gaps = 117/1076 (10%)
Query: 541 DSLIPSTSSMTHVSDTEHKESETA-------VETSTPKIKTGSSSLEGQFPNE----GIA 589
++ + + S T + TE E+ TA ST +T ++S G P G
Sbjct: 243 ETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSE 302
Query: 590 IDMELQSDPEEQLSENACISETSFSSESPEGACTSLPSPGGETQSTSEESCTPASL---E 646
M PE A T+ + E S T ST+ T AS+ E
Sbjct: 303 TTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSE 362
Query: 647 TTFCSEVSS---TENTDKYNQRNSTDENFHASLMSEISPISTSPEISEASLMSNLPLTSE 703
T+ S S T +T+ ++ E A+ +S +T+ I+++ + SE
Sbjct: 363 TSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSE 422
Query: 704 ASPVSN--LPLTSETSPMSDLPLTSETSSVSSMLLT--SETTFVSSL--------PLPSE 751
+ VS T+ ++ S++ + S + S ++ T SETT V++ SE
Sbjct: 423 MTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSE 482
Query: 752 TSPISNSSINERMAHQQRKSPSVSEEPLSPQKDESSATAKPLGENLTSQQKNLSNT---- 807
T+ SN+ + + + S + E++A + E T + NT
Sbjct: 483 TTTASNTGLETTTVFTIGSDTTTA----STEGSETTAVSATGSEMTTVSTEGSENTTVST 538
Query: 808 --PEPIIMSSSSIAPEAFPSEDLHNKTLSQQTCKSHVDTEKPYPASIPELASTEMIKV-- 863
E +S++ + +E T+S ++ D+ + + A +E V
Sbjct: 539 TGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVST 598
Query: 864 ---KNHSVLQRTEKKVLPSPLELSVFSEGTDNKGNELPSAKLQDKQYISSVDKAPFSEGS 920
+N + + S + T + S + + +S+ D +
Sbjct: 599 ADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVST 658
Query: 921 RNKTHKQGSTQSRLETSHTSKSSEPSKSPDGIRNESRDSEISKRKTAEQHSFGICKEKRA 980
ST+ T+ ++ SE + S +G + + I+ +T + + G +
Sbjct: 659 TGSERTITSTEGSETTTVSATGSETTVSTEG--SGTTTVSITGSETTKVSTTGSETTTTS 716
Query: 981 RIEDDQSTRNISSSSPPEKEQPPREEPRVPPLKIQLSKIGPPFIIKSQ-PVSKPESRAST 1039
+ +T +I+ S E E + S+ S+ + S +T
Sbjct: 717 TEGSEITTASITGS---ETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETT 773
Query: 1040 STSVSGGRNTGARTLADIKARAQQARAQ--------REAAAAAAVAAAASIVSGA----- 1086
S+ G T A T+ + A ++ E A+ A+ + VS A
Sbjct: 774 MASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETI 833
Query: 1087 -MGSPGEGGKTRTLAHIKEQTKAKLFAKHQARAHLFQTSKETRLPPPLSSKEGPPNLEVS 1145
+ G T T E T A A S ET + S+ + E S
Sbjct: 834 PASTAGSETTTTTSTEGSETTTASTEGSETTTAS--TESSETTTATTIGSETTTASTEGS 891
Query: 1146 STPETKMEGSTGVIIVNPNCRSPSNKSAHLRETTTVLQQSLNPSKLPETATDLSVHSSDE 1205
T T EGS + S + + + +T ++ S T S S+
Sbjct: 892 ETTTTSTEGS--------ETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSEL 943
Query: 1206 NIPVSHLSEKI-VSSTSSENSSVPMLFNKNSVPVSVCSTAISGAIKEHPFVSSVDKSSVL 1264
+ SE I VS+ SE ++V + ++ +T S A E VS+ +
Sbjct: 944 TTVSTTGSETITVSAEGSETTTVTTMGSE--------TTTASTAGSETTTVSTAGSETTT 995
Query: 1265 MSVDSANTTISACNISMLKTIQGTDTPCIAIIPKCIESTPI-SATTEGSSISSSMDDKQL 1323
S++ + TT + S T+ T T + E+T + +A +E +++ ++ +
Sbjct: 996 ASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTT 1055
Query: 1324 LISSSSASNLVSTQYTSVPTPSIGNNLPNLSTSSVLIPPMGINNRFPSEKIAIPGSEEQA 1383
+ S + VST + T S +L T++V G + + GSE
Sbjct: 1056 TSTEGSETTTVSTTGSETTTASTA----DLETTTVSTSGSG------TTTASTAGSETTT 1105
Query: 1384 TVSMGTTVRAALSCSDSVAVTDSLVAHPTVAMFTGNMLTINSYDSPPKLSAESLDKNSGP 1443
G+ A + + + T A TG+ +T + ++ +
Sbjct: 1106 VYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATT 1165
Query: 1444 RNRADNSGKPQQPPGGFAPAAINRSIPCKVIVDHSTTLTSSLSLTVSVESSEASLDLQGR 1503
+ A + G A S T T+S T E++ AS
Sbjct: 1166 SSAAGSEATTTSTEGSETTTASTAG---------SETTTAS---TAGSETTTAS------ 1207
Query: 1504 PVRTEASVQPVACPQVSVISRPEPVANEGIDHSSTFIAASAAKQDSKTLPATCTSL 1559
T S AC S S P +E +++ I + + +L T TSL
Sbjct: 1208 ---TSGSETNTACTTGSETSTPSSAGSE--TNTAFIIGSETTIASTASLEPTATSL 1258
Score = 69.3 bits (168), Expect = 4e-11
Identities = 177/921 (19%), Positives = 327/921 (35%), Gaps = 110/921 (11%)
Query: 547 TSSMTHVSDTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMELQSDPEEQLSENA 606
T S T + TE E TAV T+ + T S+ EG I + SD E
Sbjct: 409 TDSETTTTCTEGSEM-TAVSTTVFETTTAST--------EGSEITIASTSDSET------ 453
Query: 607 CISETSFSSESPEGACTSLPSPGGETQS---TSEESCTPAS--LETTFCSEVSSTENTDK 661
T+ S+E E T++ + G ET++ T E+ T ++ LETT + S T
Sbjct: 454 ----TTASTEGSE--TTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTAS 507
Query: 662 YNQRNSTDENFHASLMSEISP-------ISTSPEISEASLMSNLPLTSEASPVSNLPLTS 714
+T + S M+ +S +ST+ + + L T+ ++ S + S
Sbjct: 508 TEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVS 567
Query: 715 ETSPMSDLPLTSETSSVSSMLLTSETTFVSSLPLPSETSPISNSSINERMAHQQRKSPSV 774
T + T + + ++ SETT VS+ + T+ ++S S +
Sbjct: 568 TTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSA-------STTG 620
Query: 775 SEEPLSPQKDESSATAKPLGENLTSQQKNLSNTPEPIIMSSSSIAPEAFPS-EDLHNKTL 833
SE + + TA G T+ +S T M S++ + S E T+
Sbjct: 621 SETTTASTTSSETTTASTEGSETTT----VSTTDSETTMVSTTGSERTITSTEGSETTTV 676
Query: 834 SQQTCKSHVDTEKPYPASIPELASTEMIKVK---NHSVLQRTEKKVLPSPLELSVFSEGT 890
S ++ V TE ++ + +E KV + + TE + + +
Sbjct: 677 SATGSETTVSTEGSGTTTV-SITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTA 735
Query: 891 DNKGNELPSAKLQDKQYISSVDKAPFSEGSRNKTHKQGSTQSRLET-------------S 937
+G+E +A + + S+ + GS T S+++ + + S
Sbjct: 736 STEGSETTTASTEGSETTSAS-----TTGSETTTASTTSSETTMASIMGSETTMASTIGS 790
Query: 938 HTSKSSEPSKSPDGIRNESRDSEISKRKTAEQHSFGICKEKRARIEDDQS-TRNISSSSP 996
T+K S S + E+ ++ I+ +E + + S T +S+
Sbjct: 791 ETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEG 850
Query: 997 PEKEQPPREEPRVPPLKIQLSKIGPPFIIKSQPVS-KPESRASTSTSVSGGRNTGART-- 1053
E E + S+ I S+ + E +T+TS G T A T
Sbjct: 851 SETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEG 910
Query: 1054 -----LADIKARAQQARAQREAAAAAAVAAAASIVSGAMGSP-----GEGGKTRTLAHIK 1103
++ + A + A+ + GS EG +T T+ +
Sbjct: 911 SEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMG 970
Query: 1104 EQTKAKLFAKHQARAHLFQTSKETRLPPPLSSKEGPPNLEVSST-PETKMEGSTGVIIVN 1162
+T A + S+ T +S EG VSST ET +TG
Sbjct: 971 SETTTASTAGSETTTVSTAGSETTT-----ASIEGSETTTVSSTGSETTTVSTTGT---- 1021
Query: 1163 PNCRSPSNKSAHLRETTTVLQQSLNPSKLPETATDLSVHSSDENIPVSHLSEKIVSSTSS 1222
+ S ETTTV + + T ++ + S++ + + VS+T S
Sbjct: 1022 ----ETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTT------VSTTGS 1071
Query: 1223 ENSSVPMLFNKNSVPVSVCSTAISGAIKEHPFVSSVDKSSVLMSVDSANTTISACNISML 1282
E ++ + + + ST+ SG S+ + + + + TT ++ S
Sbjct: 1072 ETTTA----STADLETTTVSTSGSGTTT----ASTAGSETTTVYITGSKTTTASTEGSEA 1123
Query: 1283 KTIQGTDTPCIAIIPKCIESTPISAT-TEGSSISSSMDDKQLLISSSSASNLVSTQYTSV 1341
T+ T + E T + T +E +++S+ + ++ S + ST+ +
Sbjct: 1124 TTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSET 1183
Query: 1342 PTPSIGNNLPNLSTSSVLIPPMGINNRFPSEKIAIPGSEEQATVSMGTTVRAALSCSDSV 1401
T S + ++++ + + GSE S G+ A
Sbjct: 1184 TTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSET 1243
Query: 1402 AVTDSLVAHPTVAMFTGNMLT 1422
+ + PT TG+ T
Sbjct: 1244 TIASTASLEPTATSLTGSETT 1264
Score = 62.4 bits (150), Expect = 5e-09
Identities = 201/1062 (18%), Positives = 359/1062 (33%), Gaps = 147/1062 (13%)
Query: 542 SLIPSTSSMTHVSDTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMELQSDPEEQ 601
++ P+ S T + T E+ T + ++ ++ E P+ + + E
Sbjct: 6 TVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEI 65
Query: 602 LSENACISETSFSSESPEGACTSLPSPGGETQSTSEESCTPASLETTFCSEVSSTENTDK 661
+ + SE + S + G T+ + T ST+ T S+ T + VS+ +
Sbjct: 66 TTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETT 125
Query: 662 YNQRNSTDENFHASLMSEISPISTSPEISEASLMSNLPLTSEASPVSNLPLTSETSPMSD 721
N S++ ++ SE + +ST + + ++ T+ ++ S + +
Sbjct: 126 TNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETI 185
Query: 722 LPLT--SETSSVSSMLLTSETTFVSSLPLPSETSPISNSSINERMAHQQRKSPS-VSEEP 778
P T SET++VS+ SETT VS+ SET+ S AH + + S + E
Sbjct: 186 TPSTAGSETTTVSTA--GSETTTVSTTG--SETTTAST-------AHSETTAASTMGSET 234
Query: 779 LSPQKDESSATAKPLGENLTSQQKNLSNTPEPIIMSSSSIAPEAFPSEDLHNKTLSQQTC 838
S T G T+ S T +ED T S
Sbjct: 235 TKVSTAGSETTVSTAGSETTAASTEDSETNTAF-------------TEDSKTTTASTTGF 281
Query: 839 KSHVDTEKPYPASIPELASTEMIKVKNHSVLQRTEKKVLPSPLELS-VFSEGTDNKGNEL 897
++ T S P +AST + S + KV + E++ VF+ G++
Sbjct: 282 ET---TAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRAST 338
Query: 898 PSAKLQDKQYISSVDKAPFSEGSRNKTHKQGSTQSRLETSHTSKSSEPSKSPDGIRNESR 957
++ S GS T +T S T+ T S + S +G +
Sbjct: 339 VGSETTTVSTTGSETTTASIMGSETST--DSTTGSETTTASTEGSETTTASTEGSEATTV 396
Query: 958 DSEISKRKTAEQHSFGICKEKRARIEDDQSTRNISSSSPPEKEQPPREEPRVPPLKIQLS 1017
+ S+ T I D ++T + S +++
Sbjct: 397 STTGSETTTVS-------------ITDSETTTTCTEGS-------------------EMT 424
Query: 1018 KIGPPFIIKSQPVSKPESRASTSTSVSGGRNTGARTLADIKARAQQARAQREAAAAAAVA 1077
+ + + E T S S T A T + + A +
Sbjct: 425 AVSTT--VFETTTASTEGSEITIASTSDSETTTAST--------EGSETTTVTTAGSETK 474
Query: 1078 AAASIVSGAMGSPGEGGKTRTLAHIKEQTKAKLFAKHQARAHLFQTSKETRLPPPLSSKE 1137
A + S + G +T T+ I T + A S+ T + S E
Sbjct: 475 TAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTV-----STE 529
Query: 1138 GPPNLEVSST-PETKMEGSTGVIIVNPNCRSPSNKSAHLRETTTVLQQSLNPSKLPETAT 1196
G N VS+T ET +TG+ ETTT + + + T
Sbjct: 530 GSENTTVSTTGSETTTVSTTGL------------------ETTTTSTEGSEMTTVSTTGA 571
Query: 1197 DLSVHSSDENIPVSHLSEKIVSSTSSENSSVPMLFNKNSVPVSVCSTAISGAIKEHPFVS 1256
+ + S++ + S+ SE ++V ++N T S A E S
Sbjct: 572 ETTTDSTEGS------GTTAASTAGSETTTVSTADSEN--------TTASTADSETTSAS 617
Query: 1257 SVDKSSVLMSVDSANTTISACNISMLKTIQGTDTPCIAIIPKCIESTPISATTEGSSISS 1316
+ + S S+ TT ++ S T+ TD+ E+T +S T +I+S
Sbjct: 618 TTGSETTTASTTSSETTTASTEGSETTTVSTTDS----------ETTMVSTTGSERTITS 667
Query: 1317 SMDDKQLLISSSSASNLVSTQYTSVPTPSI-----------GNNLPNLSTSSVLIPPMGI 1365
+ + +S++ + VST+ + T SI G+ ST I I
Sbjct: 668 TEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASI 727
Query: 1366 NNRFPSEKIAIPGSEEQATVSMGTTVRAALSCSDSVAVTDSLVAHPTVAMFTGNMLTINS 1425
+ + GSE + G+ +A + + + T+A G+ T+ S
Sbjct: 728 TGS-ETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMAS 786
Query: 1426 ---YDSPPKLSAESLDKNSGPRNRADNSGKPQQPPGGFAPAAINRSIPCKVIVDHSTTLT 1482
++ +A S N A + +IP +TT T
Sbjct: 787 TIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTT 846
Query: 1483 SSLSLTVSVESSEASLDLQGRPVRTEASVQPVACPQVSVISRPEPVANEGIDHSSTFIAA 1542
S+ + S+E S + TE+S A ++ S + EG + ++T
Sbjct: 847 STEGSETTTASTEGS---ETTTASTESSETTTA---TTIGSETTTASTEGSETTTTSTEG 900
Query: 1543 S---AAKQDSKTLPATCTSLRELPLVPDKLNEPTAPSHNFAE 1581
S A + + T+ E + +E T S +E
Sbjct: 901 SETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSE 942
Score = 49.3 bits (116), Expect = 4e-05
Identities = 144/771 (18%), Positives = 258/771 (33%), Gaps = 98/771 (12%)
Query: 1039 TSTSVSGGRNTGARTLADIKARAQQARAQREAAAAAAVAAAASIVS------GAMGS--- 1089
T+TS +G NT + A A ++ + A + SI AMGS
Sbjct: 66 TTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETT 125
Query: 1090 ------------PGEGGKTRTLAHIKEQTKAKLFAKHQARAHLFQTSKETRLPPPLSSKE 1137
G +T T++ + +T A + A T E S+
Sbjct: 126 TNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTA-ASTTGSEMTTVFTAGSET 184
Query: 1138 GPPNLEVSSTPETKMEGSTGVIIVNPNCRSPSNKSAHLRETTTVLQQSLNPSKLPETATD 1197
P+ S T GS + + + +AH ETT +K+ ++
Sbjct: 185 ITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAH-SETTAASTMGSETTKVSTAGSE 243
Query: 1198 LSVHSSDENIPVSHLSEKIVSSTSSENSSVPMLFNKNSVPVSVC-----STAISGAIKEH 1252
+V ++ ++ S+E+S F ++S + +TA S E
Sbjct: 244 TTVSTAGSE----------TTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEP 293
Query: 1253 PFVSSVDKSSVLMSVDSANTTISACNISMLKTIQGTDTPCIAIIPKCIESTPISATTEGS 1312
S++ + + S TT + S + T+ + I E+T +S T +
Sbjct: 294 TMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSET 353
Query: 1313 SISSSMDDKQLLISSS-SASNLVSTQYTSVPTPSI-GNNLPNLSTSSVLIPPMGINNRFP 1370
+ +S M + S++ S + ST+ + T S G+ +ST+
Sbjct: 354 TTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTG-----------SE 402
Query: 1371 SEKIAIPGSEEQATVSMGTTVRAALSCSDSVAVTDSLVAHPTVAMFTGNMLTINSYDSPP 1430
+ ++I SE T + G+ + A + V T A G+ +TI S
Sbjct: 403 TTTVSITDSETTTTCTEGSEMTA----------VSTTVFETTTASTEGSEITIASTSDSE 452
Query: 1431 KLSAESLDKNSGPRNRADNSGKPQQPPGGFAPAAINRSIPCKVI--VDHSTT-------- 1480
+A + + A + K G A N + + + TT
Sbjct: 453 TTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSE 512
Query: 1481 -----LTSSLSLTVSVESSE-ASLDLQGRPVRT------EASVQPVACPQVSVISRPEPV 1528
T S TVS E SE ++ G T E + +++ +S
Sbjct: 513 TTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAE 572
Query: 1529 ANEGIDHSSTFIAASAAKQDSKTLPATCTSLRELPLVPDKLNEPTAPSHNFAEQARGPAP 1588
S AAS A ++ T+ +T S D +E T+ S +E A
Sbjct: 573 TTTDSTEGSGTTAASTAGSETTTV-STADSENTTASTAD--SETTSASTTGSETT--TAS 627
Query: 1589 FKSEADTTCSNQYNPSNRICWNDDG---MRSTG-QPLVTHSGSSKQKEYLEQSCPKAIKT 1644
S TT S + + + + D + +TG + +T + S+ + T
Sbjct: 628 TTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVST 687
Query: 1645 EHANYLNVSELHPRNLVTNVALPVKSELHEADKGFRMDTEDFPGPELPPPAAEGA----S 1700
E + VS T V+ + +G + T G E + EG+ +
Sbjct: 688 EGSGTTTVSITGSE--TTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTA 745
Query: 1701 SVQQTQNMKASTSSPMEEAISLATDALKRVPGAGSSGCRLSSVEANNPLVT 1751
S + ++ AST+ S + GS S++ + V+
Sbjct: 746 STEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVS 796
Score = 43.5 bits (101), Expect = 0.002
Identities = 93/473 (19%), Positives = 165/473 (34%), Gaps = 39/473 (8%)
Query: 373 TTGPNNAGAQSSSSCGTSGLPVSAQTALAEQQPKSMKSPASPEPGFCATLCPMVEIPPKD 432
TT + G++++S+ T +A T +E S+ G T+ +
Sbjct: 742 TTTASTEGSETTSASTTGSETTTASTTSSETTMASIM-------GSETTMASTIGSETTK 794
Query: 433 IMAELESEDILIPEESVIQEEIAEEVETSICECQDENHKTIPEFSEEAESLTNSHEEPQ- 491
+ + E S + IA + +TIP + +E+ T + E
Sbjct: 795 VSTASSKMTTVFTENS--ETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSE 852
Query: 492 -IAPPEDNLESCVMMNDVLETLPHIEVKIEGKSESPQEEMTVVIDQLEVCDSLIPSTSSM 550
+ E+ + ET + E + S + T + S
Sbjct: 853 TTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTS----------TEGSE 902
Query: 551 THVSDTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMEL---QSDPEEQLSENAC 607
T + TE E T ST +T ++S EG EL + E ++ +A
Sbjct: 903 TTTASTEGSEITTV---STTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAE 959
Query: 608 ISETSFSSESPEGACTSLPSPGGE---TQSTSEESCTPASLETTFCSEVSSTENTDKYNQ 664
SET+ + + G+ T+ S G T ST+ T AS+E + + VSST +
Sbjct: 960 GSETT--TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVS 1017
Query: 665 RNSTDENFHASLMSEISPISTSPEISEASLMSNLPLTSEASPVSNLPLTSETSPMSDLPL 724
T+ ++ SE + ++T+ + A + T+ ++ S S T +
Sbjct: 1018 TTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTAS 1077
Query: 725 TSETSSVSSMLLTSETTFVSSLPLPSETSPISNSSINERMAHQQRKSPSVSEEPLSPQKD 784
T++ + + S TT S+ + T I+ S S SE
Sbjct: 1078 TADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTT-------TASTEGSEATTVSTTS 1130
Query: 785 ESSATAKPLGENLTSQQKNLSNTPEPIIMSSSSIAPEAFPSEDLHNKTLSQQT 837
+ TA G +T+ +S T + S + A SE T +T
Sbjct: 1131 SETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSET 1183
Score = 40.8 bits (94), Expect = 0.015
Identities = 71/320 (22%), Positives = 121/320 (37%), Gaps = 36/320 (11%)
Query: 1269 SANTTISACNISMLKTIQGTDTPCIAIIPKCIESTPISATTEGSSISS-SMDDKQLLISS 1327
S+ TT++ S T T + I+ K E+T +A+T GS ++ S Q I S
Sbjct: 2 SSETTVAPAAGSNTTTASTTGSETTTILIKASETT--TASTAGSETTTPSPTGSQTTIVS 59
Query: 1328 SSASNLVST-----QYTSVPTPSIGNNLPNLSTSSVLIPPMGINNRFPSEKIAIPGSEEQ 1382
S S + +T + T+V + G +++ S + G + ++I G+E
Sbjct: 60 ISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSE----TTTVSITGTETT 115
Query: 1383 ATVSMGTTVRAALSCSDSVAVTDSLVAHPTVAMFTGNMLTINSYDSPPKLSAESLDKNSG 1442
+MG+ + S VT + + T G+ T +Y + + +A
Sbjct: 116 MVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSE-TTTAYTADSETTA-------- 166
Query: 1443 PRNRADNSGKPQQPPGGFAPAAINRSIPCKVIVDHSTTLTS--SLSLTVSVESSEASLDL 1500
A +G A + +I +TT+++ S + TVS SE +
Sbjct: 167 ----ASTTGSEMTT----VFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTAS 218
Query: 1501 QGRPVRTEASVQPVACPQVSVISRPEPVANEGIDHSSTFIAAS----AAKQDSKTLPATC 1556
T AS +VS V+ G + ++ S A +DSKT A+
Sbjct: 219 TAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTAST 278
Query: 1557 TSLRELPLVPDKLNEPTAPS 1576
T E +EPT S
Sbjct: 279 TGF-ETTAASTTGSEPTMAS 297
Score = 40.8 bits (94), Expect = 0.015
Identities = 75/341 (21%), Positives = 131/341 (38%), Gaps = 39/341 (11%)
Query: 459 ETSICECQDENHKTIPEFSEEAESLTNSHEEPQIAPPEDNLESCVMMNDVLETLPHIEVK 518
ET+I + T+ E ++ + E E + E+ + ET
Sbjct: 1022 ETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGS-ETTTVSTTGSETTTASTAD 1080
Query: 519 IEGKSESPQEEMTVVIDQLEVCDSLIPSTSSMTHVSDTEHKESETAVETSTPKIKTGSSS 578
+E + S T + + T S T + TE E+ T TS+ +T ++S
Sbjct: 1081 LETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSS---ETTTAS 1137
Query: 579 LEGQFPNEGIAIDMELQSDPEEQLSENACISETSFSSESPEGACTSLPSPGGETQSTSEE 638
G E + +SET+ S A TS + G E +TS E
Sbjct: 1138 TTGS-----------------EMTTVFTTVSETTTVSTIGSEATTS-SAAGSEATTTSTE 1179
Query: 639 -----SCTPASLETTFCSEVSSTENTDKYNQRNSTDENFHASLMSEIS-PISTSPEISEA 692
+ + A ETT S S T + ++ N + SE S P S E + A
Sbjct: 1180 GSETTTASTAGSETTTASTAGSETTTAS---TSGSETNTACTTGSETSTPSSAGSETNTA 1236
Query: 693 SLMSN---LPLTSEASPVSNLPLTSETSPMSDLPLTSETSSVSSMLLTSETTFVSSLPLP 749
++ + + T+ P + SET+ +S +T+ ++ +S + S TTFV +
Sbjct: 1237 FIIGSETTIASTASLEPTATSLTGSETTTVS---ITASGATAASTTV-SSTTFVLTKATD 1292
Query: 750 SETSPISNSSINERMAHQQRKSPSVSEEPLSPQKDESSATA 790
PI+N+ ++ R + S S ++P D +++ A
Sbjct: 1293 VSIQPITNTPMSGTRTTGTRPTAS-SSVTMAPGMDFTASAA 1332
>gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]
Length = 2089
Score = 67.0 bits (162), Expect = 2e-10
Identities = 211/1064 (19%), Positives = 382/1064 (35%), Gaps = 165/1064 (15%)
Query: 210 SDKEMKHGQKSPTGKQTSQHLKRLKKSGLGHLKWTKAEDIDIETPGSILVNTNLRALINK 269
S + + G + PTG++ QH+ K S + +ED+D++ L N L A+
Sbjct: 658 STQPQREGAQVPTGREREQHVGGTKDS---EDNYGDSEDLDLQATQCFLENQGLEAV--- 711
Query: 270 HTFASLPQHFQQYLLLLLPEVDRQMGSDGILRLSTSALNNEFFAYAAQGWKQRLAEGEFT 329
S+ Q +L P+ ++G +T L+ + A Q + R +E
Sbjct: 712 ---QSMEDEPTQAFMLTPPQ---ELGPSHCSFQTTGTLDEPWEVLATQPFCLRESE---- 761
Query: 330 PEMQLRIRQEIEKEKKTEPWKEKFFERFYGEKLGMSREESVKLTTGPNNAGAQSSSSCGT 389
+ +T+P+ YG L R P + +S
Sbjct: 762 -------------DSETQPFDTHL--EAYGPCLSPPRAI-------PGDQHPESPVHTEP 799
Query: 390 SGLPVSAQTALAEQQ--PKSMKSPASPEPGFCATLCPMVEIPPKDIMAELESEDILIPEE 447
G+ + + + PK PE G P+ E E+E +L PE
Sbjct: 800 MGIQGRGRQTVDKVMGIPKETAERVGPERG------PL----------ERETEKLL-PER 842
Query: 448 SVIQEEIAEEVETSICECQDENHKTIPEFSEEAESLTNSHEEPQIAPPEDNLESCVMMND 507
Q ++ E E + + E + + ++ ES N A PE + ES +
Sbjct: 843 ---QTDVTGEEELTKGKQDREQKQLLARDTQRQESDKNGES----ASPERDRES---LKV 892
Query: 508 VLETLPHIEVKIEGKSESPQEEMTVVIDQLEV---CD--SLIPSTSSMTHVSDTEHKESE 562
+ET I+ K K P + +++ CD L + DT+ E E
Sbjct: 893 EIETSEEIQEKQVQKQTLPSKAFEREVERPVANRECDPAELEEKVPKVILERDTQRGEPE 952
Query: 563 TAVE-------TSTPKIKTGSSSLEG----------QFPNEGIAID--------MELQSD 597
+ + TP+ G+ L G Q G + + +
Sbjct: 953 GGSQDQKGQASSPTPEPGVGAGDLPGPTSAPVPSGSQSGGRGSPVSPRRHQKGLLNCKMP 1012
Query: 598 PEEQLSENACISETSFSSESPEGACT-----SLPSPGGET-QSTSEESCTPASLETTFCS 651
P E+ S + S + AC P+P + S S++ P L +
Sbjct: 1013 PAEKASRIRAAEKVSRGDQESPDACLPPTVPEAPAPPQKPLNSQSQKHLAPPPLLSPL-- 1070
Query: 652 EVSSTENTDKYNQRNSTDENFHASLMSEISPISTSPEI--SEASLMSNLPLTSEASPVSN 709
+ S + T + +++ + E A L SE+ P P+I ++S M+ P TS A+P +
Sbjct: 1071 -LPSIKPTVRKTRQDGSQEAPEAPLSSELEPFHPKPKIRTRKSSRMTPFPATS-AAPEPH 1128
Query: 710 LPLTSETSPMSDLPLTSETSSVS--SMLLTSETTFVSSLPLPSETS---PISNSSINERM 764
P TS P++ P + T S + S + T E ++ L TS P+++ ++
Sbjct: 1129 -PSTSTAQPVTPKPTSQATRSRTNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTSQVT 1187
Query: 765 AHQQRKSPSVSEEPLSP---QKDESSATAKPLGENLTSQ----QKNLSN--TPEPIIMSS 815
++ +S + E + P + S++T +P+ TSQ +KN S+ TPEP++ ++
Sbjct: 1188 RGRKSRSSVKTPETVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRSSVKTPEPVVPTA 1247
Query: 816 SSIAPEAFPSEDLHNKTLSQQT----CKSHVDTEKPYPASIPELASTEMIKVKNHSVLQR 871
+ P + + ++ Q T +S V T +P + PEL +
Sbjct: 1248 PELQPSTSTDQPVTSEPTYQATRGRKNRSSVKTPEPVVPTAPELRPS-----------TS 1296
Query: 872 TEKKVLPSPLELSVFSEGTDNKGNELPSAKL--QDKQYISSVDKAPFSEGSRNKTHKQGS 929
T++ V P P + S T+ + P + + IS+ P + ++T + +
Sbjct: 1297 TDRPVTPKPTSRTTRSR-TNMSSVKTPETVVPTAPELQISTSTDQPVTPKPTSRTTRSRT 1355
Query: 930 TQSRLETSHTSKSSEPSKSPDGIRNESRDSEISKRKTAEQHSFGICKEKRARIEDDQSTR 989
S ++ ++ P P + E + R T + + K +
Sbjct: 1356 NMSSVKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRGRKNRSSGKTPETLVPTAPKLE 1415
Query: 990 NISSSSPPEKEQPPREEPRVPPLKIQLSKIGPPFIIKSQPVSKPESRASTSTSVSGGRNT 1049
+S+ P +P + R + S + P ++ + PE + STST
Sbjct: 1416 PSTSTDQPVTPEPTSQATRG---RTNRSSVKTP---ETVVPTAPELQPSTSTDQPVTPEP 1469
Query: 1050 GARTLADIKARAQQARAQREAAAAAAVAAAASIVSGAMGSPGEGGKTRTLAHIKEQTKAK 1109
++ R+ + A + A+AS P +RT K ++ K
Sbjct: 1470 TSQATRGRTDRSSVKTPETVVPTAPELQASASTDQPVTSEP----TSRTTRGRKNRSSVK 1525
Query: 1110 LFAKHQARAHLFQTSKETRLP----PPLSSKEGPPNLEVSSTPET------KMEGSTG-- 1157
A Q S T P P + G N TPE+ +++ ST
Sbjct: 1526 TPETVVPAAPELQPSTSTDQPVTPEPTSRATRGRTNRSSVKTPESIVPIAPELQPSTSRN 1585
Query: 1158 -VIIVNPNCRSPSNKSAHLRETTTVLQQSLNPSKLPETATDLSV 1200
++ P R+ ++ T P P T+TD V
Sbjct: 1586 QLVTPEPTSRATRCRTNRSSVKTPEPVVPTAPEPHPTTSTDQPV 1629
>gi|239754668 PREDICTED: mucin 12 [Homo sapiens]
Length = 1952
Score = 66.2 bits (160), Expect = 3e-10
Identities = 255/1299 (19%), Positives = 439/1299 (33%), Gaps = 149/1299 (11%)
Query: 383 SSSSCGTSGLPVSAQTA-LAEQQPKSMKSPASPEPGFCATLCPMVEIPPKDIMAELE--- 438
+S+S T+ LP S TA L+E+ SP SP+ + K +
Sbjct: 179 TSASMETTALPGSTTTAGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGP 238
Query: 439 SEDILIPE---------ESVIQEEIAEEVETSICECQDENHKTIPEFS--EEAESLTNSH 487
+ I P+ ES I +T++ PE + + T +
Sbjct: 239 THTIAFPDSTTMPGVSQESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTT 298
Query: 488 EEPQIAPPEDNLESCVMMNDVLETLPHIEVKIEGKSESPQEEMTVVIDQLEVCDSLIPS- 546
P LE+ ++ + PH + + E T S PS
Sbjct: 299 RLPDNTTTSGLLEASTPVHSSTGS-PHTTLSPASSTTHEGEPTTFQSWPSSKDTSPAPSG 357
Query: 547 -TSSMTHVSDTEHKESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMELQSDPEEQLSEN 605
TS+ +S T H + T T E P + + P + + +
Sbjct: 358 TTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPVHSSPV-ATATTPPPARSATS 416
Query: 606 ACISETSFSSESPEGACTSLPSPGGETQSTSEESC----------------TPASLETTF 649
+ E++ SP T T SEES T A T++
Sbjct: 417 GHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSY 476
Query: 650 CSEVSSTENT-----DKYNQRNSTDENFHAS---LMSEISPISTSPEI----SEASLMSN 697
S + STE T + R+ + H+S + + + P ++P + S S +S+
Sbjct: 477 HSSLGSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISS 536
Query: 698 LPLTSEASPVSNLP--LTSETSPMSDLPLTSET----SSVSSMLLTSETTFVSSLPLPSE 751
+ + A P S L+ +++ P + +T +S++S ++ E+T S P +
Sbjct: 537 GSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTH 596
Query: 752 TSPISNSSINERMAHQ---QRKSPSVSEEPLSPQKDESSATAKPLGENLTSQQKNLSNTP 808
T+ S+ ++ + SP ++ LSP S TA LG T+ +T
Sbjct: 597 TTAFPGSTTMPGLSQESTASHSSPGPTDTTLSP----GSTTASSLGPEYTTFHSRPGSTE 652
Query: 809 EPIIMSSSSIAPEAFPSEDLHNKTLSQQTCKSHVDTEKPYPASIPELASTEMIKVKNHSV 868
++ +++ + S +H+ T S T T P ++ + ST HS
Sbjct: 653 TTLLPDNTTASGLLEASMPVHSSTRSPHT------TLSPAGSTTRQGESTTF-----HSW 701
Query: 869 LQRTEKKVLPSPLELSVFSE-GTDNKG--NELPSAKLQDKQYISSVDKAP----FSEGSR 921
+ + P P S F E T + G + +P+ + + S + + S GS
Sbjct: 702 PSSNDTRPAP-PTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGST 760
Query: 922 NKTH--KQGSTQSRLE---TSHTSKSSEPSKSPDGIRNESRDSEISKRKTAEQHSFGICK 976
H + +T R E TSH+S + S +P S S + + T+ S G
Sbjct: 761 QTMHFPESDTTSGRGEESTTSHSSTTHTISSAP------STTSALVEEPTSYHSSPG--S 812
Query: 977 EKRARIEDDQSTRNISSSSPPEKEQPPREEPRVPPLKIQLSKIGPPFIIKSQPVSKPESR 1036
D +T S S V P + S ++ + + P S
Sbjct: 813 TATTHFPDSSTTSGRSEESIASHSSQDATGTIVLPARSTNS------VLLGESTTSPISS 866
Query: 1037 ASTSTSVSGGRNTGARTLADIKARAQQARAQREAAAAAAVAAAASIVSGAMGSPGEGGKT 1096
S T+ G +T L++ + + A ++ + + S G T
Sbjct: 867 GSMETTALPG-STTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGST 925
Query: 1097 RTLAHIKEQTKAKLFAKHQARAHLFQTSKETRLPPPLSSKEGPPNLEVSSTPETKMEGST 1156
T A + T ++H +H S +T L P ST
Sbjct: 926 HTTA-FPDSTTTPGLSRHSTTSHSSPGSTDTTLLP----------------------AST 962
Query: 1157 GVIIVNPNCRSPSNKSAHLRETTTVLQQSLNPSKLPETATDL--SVHSSDENIPVSHLSE 1214
+V SP + + TT L S + L E +T S S D + + +
Sbjct: 963 TTXLVGEPTTSPISSGS---TETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTS 1019
Query: 1215 KIVSSTSSENSSVPMLFNKNSVPVSVCSTAIS-GAIKEHPFVSSVD-----KSSVLMSVD 1268
VS S+ + S P + + P S +S + H S D +S+ S+
Sbjct: 1020 SGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPRSTTASSLG 1079
Query: 1269 SANTTISACNISMLKTIQGTDTPCIAIIPKCIESTPI-SATTEGSSISSSMDDKQLLISS 1327
+TT + S T+ +T ++ STP+ S+T + S S
Sbjct: 1080 PESTTFHSGPGSTETTLLPDNTTASGLLE---ASTPVHSSTGSPRTTLSPAGSTTRQGES 1136
Query: 1328 SSASNLVSTQYTSVPTPSIGNNLPNLSTSSVLIPPMGINNRFPSEKIAIPGSEEQATVSM 1387
++ + S++ T P+ + LST+S P F + SEE TV
Sbjct: 1137 TTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSIPTTHFSASSTTFGRSEESTTVH- 1195
Query: 1388 GTTVRAALSCSDSVAVTDSLVAHPTVAMFT-GNMLTINSYDSPPKLSAESLDKNSGPRNR 1446
+ V A + S + + T LV T + G+ T++ +S + S
Sbjct: 1196 SSPVAPATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTT 1255
Query: 1447 ADNSGKPQQPPGGFAPAAINRSIPCKVIVDHSTTLTSSLSLTVSVESSEASLDLQG-RPV 1505
S P S P + H +++ + +S +S D G P+
Sbjct: 1256 HTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPL 1315
Query: 1506 --------RTEASVQPVACPQVSVISRPEPVANEGIDHSSTFIAASAAKQDSKTLPATCT 1557
R S P + G+ ST + +S+ D PA+ T
Sbjct: 1316 PAHFTTSGRIAESTTFYISPGSMETTLASTATTPGLSAKSTILYSSSRSPDQTLSPASMT 1375
Query: 1558 SLRELPLVPDKLNEPTAPSHNFAEQARGPAPFKSEADTT 1596
S + P L +H A A S+ TT
Sbjct: 1376 S-SSISGEPTSLYSQAESTHTTAFPASTTTSGLSQESTT 1413
Score = 65.9 bits (159), Expect = 4e-10
Identities = 216/1029 (20%), Positives = 356/1029 (34%), Gaps = 153/1029 (14%)
Query: 604 ENACISETSFSSESPEGACTSLPSPGGETQSTSEESCTPA-------SLETTFCSEVSST 656
E I+ ++FS S T S GG T S S S + + TF + ++T
Sbjct: 70 EETVINHSTFSGFSQITGSTVNTSIGGNTTSASTPSSSDPFTTFSDYGVSVTFITGSTAT 129
Query: 657 EN-----TDKYNQRNSTDENF------------HASLMSEISPISTSPEISEASLMSNLP 699
++ T+ + ST + H++ + TSP S + + LP
Sbjct: 130 KHFLDSSTNSGHSEESTVSHSGPGATGTTLFPSHSATSVFVGEPKTSPITSASMETTALP 189
Query: 700 LTSEASPVSNLPLTSETSPMSDLPLTSETSSVSSMLLTSETTFVSSLPLPSETSPISNSS 759
++ + +S T +SP S S + SS + TT S P P+ T +S+
Sbjct: 190 GSTTTAGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTT-SHSRPGPTHTIAFPDST 248
Query: 760 INERMAHQQRKS---PSVSEEPLSPQKDESSATAKPLGENLTSQQKNLSNTPEPIIMSSS 816
++ + S P ++ LSP + T LG T+ + T + ++
Sbjct: 249 TMPGVSQESTASHSIPGSTDTTLSP----GTTTPSSLGPESTTFHSSPGYTKTTRLPDNT 304
Query: 817 SIAPEAFPSEDLHNKTLSQQTCKSHVD---------TEKPYPAS---IPELASTEMIKVK 864
+ + S +H+ T S T S T + +P+S P + T VK
Sbjct: 305 TTSGLLEASTPVHSSTGSPHTTLSPASSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVK 364
Query: 865 NHSVLQRTEKKVLPSPLELSVFSEGTDNKGNELPSAKLQDKQYISSVDKAPFSEGSRNKT 924
+ + PS + FS + G+ S + ++ P +
Sbjct: 365 LSTTYHSS-----PSSTPTTHFSASSTTLGHSEESTPVHSSPVATATTPPPARSATSGHV 419
Query: 925 HKQ-------GSTQSR--LETSHTSKSSEPSKSPDGIRNESRDSEISKRKTAEQHSF--G 973
+ GSTQ+ E+S TS SE S + G ++ S S S+
Sbjct: 420 EESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSS 479
Query: 974 ICKEKRARIEDDQSTRNISSSSPPEKEQPPREEPRVPPLKIQLSKIGPPFIIKSQPVSKP 1033
+ + D + S S P V P P ++ P
Sbjct: 480 LGSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAG------STPSVLVGDSTPSP 533
Query: 1034 ESRASTSTSVSGGRNTGARTLADIKARAQQARAQREAAAAAAVAAAASIVSGAMGSPGEG 1093
S S T+ G +T L++ + + A ++ + + S
Sbjct: 534 ISSGSMETTALPG-STTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRP 592
Query: 1094 GKTRTLAHIKEQTKAKLFAKHQARAHLFQTSKETRLPP--PLSSKEGPPNLEVSSTPETK 1151
G T T A T L ++ +H +T L P +S GP S P
Sbjct: 593 GSTHTTAFPGSTTMPGL-SQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRP--- 648
Query: 1152 MEGSTGVIIVNPNCRSPSNKSAHLRETTTVLQQSLNPSKLPETATDLSVHSSDENIPVSH 1211
GST TT+L + S L E + + VHSS + P +
Sbjct: 649 --GST---------------------ETTLLPDNTTASGLLEAS--MPVHSSTRS-PHTT 682
Query: 1212 LSEKIVSSTSSENS---SVPMLFNKNSVPVSVCSTAISGAIKEHPFVSSVDKSSVLMSVD 1268
LS ++ E++ S P + P + S + + H SS+ + +
Sbjct: 683 LSPAGSTTRQGESTTFHSWPSSNDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHI----- 737
Query: 1269 SANTTISACNISMLKTIQGTDTPCIAIIPKCIESTPISATTEGSSISSSMDDKQLLISSS 1328
SA +T S + ++ +P ES S E S+ S S + + S
Sbjct: 738 SARSTTSGL---VEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPS 794
Query: 1329 SASNLVS--TQYTSVPTPSIGNNLPNLSTSSVLIPPMGINNRFPSEKIAIPGSEEQATVS 1386
+ S LV T Y S P + + P+ ST+S SE+ S + AT
Sbjct: 795 TTSALVEEPTSYHSSPGSTATTHFPDSSTTS-----------GRSEESIASHSSQDAT-- 841
Query: 1387 MGTTVRAALSCSDSVAVTDSLVAHPTVAMFTGNMLT--INSYDSPPKLSAESLDKNSGPR 1444
GT V A S ++SV + +S T + +G+M T + + P LS S +S PR
Sbjct: 842 -GTIVLPARS-TNSVLLGES----TTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPR 895
Query: 1445 NRA--------------DNSGKPQQPPGGFAPAAINRSIPCKVIVDHSTTLTSSLSLT-V 1489
+ A + S PG A S + HSTT SS T
Sbjct: 896 SPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDT 955
Query: 1490 SVESSEASLDLQGRPVRTEASVQPVACPQVSVISRPEPVANEGIDHSSTFIAASAAKQDS 1549
++ + + L G P + P++ + P G+ ST +S D+
Sbjct: 956 TLLPASTTTXLVGEP-----TTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDT 1010
Query: 1550 KTLPATCTS 1558
PA+ TS
Sbjct: 1011 TLSPASTTS 1019
Score = 52.0 bits (123), Expect = 7e-06
Identities = 165/767 (21%), Positives = 274/767 (35%), Gaps = 106/767 (13%)
Query: 1024 IIKSQPVSKPESRASTSTSVSGGRNTGARTLADIKARAQQARAQREAAAAAAVAAAASIV 1083
+ +P + P + AS T+ G T A L++ + + + A ++ +
Sbjct: 168 VFVGEPKTSPITSASMETTALPGSTTTAG-LSEKSTTFYSSPRSPDRTLSPARTTSSGVS 226
Query: 1084 SGAMGSPGEGGKTRTLAHIKEQTKAKLFAKHQARAHLFQTSKETRLPPPLS--SKEGPPN 1141
+ S G T T+A + T ++ +H S +T L P + S GP +
Sbjct: 227 EKSTTSHSRPGPTHTIA-FPDSTTMPGVSQESTASHSIPGSTDTTLSPGTTTPSSLGPES 285
Query: 1142 LEVSSTP--------------------ETKMEGSTGVIIVNPNCR-SPSNKSAHLRETTT 1180
S+P T + STG +P+ SP++ + H E TT
Sbjct: 286 TTFHSSPGYTKTTRLPDNTTTSGLLEASTPVHSSTG----SPHTTLSPASSTTHEGEPTT 341
Query: 1181 VLQ--QSLNPSKLPETATDLSV------HSSDENIPVSHLSEKIVSSTSSENSSVPMLFN 1232
S + S P T V HSS + P +H S + SE S+ P+
Sbjct: 342 FQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEEST-PV--- 397
Query: 1233 KNSVPVSVCST------AISGAIKEHPFVSSVDKSSVLMSVDSANTTISACNISMLKTIQ 1286
+S PV+ +T A SG ++E S+ M ++TT S T
Sbjct: 398 -HSSPVATATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESA--TFH 454
Query: 1287 GTDTPCIAIIPKCIESTPISATTEGSSISSSMDDKQLLISSSSASNLVSTQYTSVPTPSI 1346
G+ T + P + ++ T+ SS+ S+ S+ S + S S P
Sbjct: 455 GSTTHTKSSTPST--TAALAHTSYHSSLGSTETTHFRDSSTISGRSEESKASHSSPDAMA 512
Query: 1347 GNNLPNLSTSSVLI---PPMGINNRFPSEKIAIPGSEEQATVS-MGTTVRAALSCSDSVA 1402
LP ST SVL+ P I++ E A+PGS + +S TT ++ D+
Sbjct: 513 TTVLPAGSTPSVLVGDSTPSPISSG-SMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTH 571
Query: 1403 VTDSLVA-----------------HPTVAMFTGNMLTINSYDSPPKLSAESLDKNSGPRN 1445
+ S+ + H T + M ++ + S D P +
Sbjct: 572 LPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGS 631
Query: 1446 RADNSGKPQQPPGGFAPAAINRSIPCKVIVDHSTT---LTSSLSLTVSVESSEASLDLQG 1502
+S P+ P + ++ + D++T L +S+ + S S +L G
Sbjct: 632 TTASSLGPEYTTFHSRPGSTETTL----LPDNTTASGLLEASMPVHSSTRSPHTTLSPAG 687
Query: 1503 RPVRTEASVQPVACPQVSVISRPEPVANEGIDHSSTFIAASAAKQDS-KTLPATCTSLRE 1561
R S + P S +RP P +S F+ S S ++P T S R
Sbjct: 688 STTRQGESTTFHSWPS-SNDTRPAPPTT-----TSAFVEPSTTSHGSPSSIPTTHISARS 741
Query: 1562 LP--LVPDKLNEPTAPSH----NFAEQ----ARGPAPFKSEADTTCSNQYNPSNRICWND 1611
LV + ++P +F E RG S + TT + PS +
Sbjct: 742 TTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVE 801
Query: 1612 DGMR---STGQPLVTHSGSSKQKEYLEQSCPKAIKTEHANYLNVSELHPRNLVTNVALPV 1668
+ S G TH S + + ++ A V L R+ TN L
Sbjct: 802 EPTSYHSSPGSTATTHFPDSSTTSGRSEESIASHSSQDATGTIV--LPARS--TNSVLLG 857
Query: 1669 KSELHEADKGFRMDTEDFPGPELPPPAAEGASSVQQTQNMKASTSSP 1715
+S G M+T PG P +E +++ + A+T SP
Sbjct: 858 ESTTSPISSG-SMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSP 903
Score = 39.7 bits (91), Expect = 0.034
Identities = 55/175 (31%), Positives = 76/175 (43%), Gaps = 20/175 (11%)
Query: 608 ISETSFSSE-----SPEGACTSLPSPGGET-QSTSEESCT----PASLETTFCSE----- 652
I+ +SF+ E S G+ S SP T SEES T P S ETT S
Sbjct: 1430 ITTSSFAQEFTTPHSQPGSALSTVSPASTTVPGLSEESTTFYSSPGSTETTAFSHSNTMS 1489
Query: 653 VSSTENTDKYNQRNSTDENFHASLMS-EISPISTS-PEISEASLMSNLPLTSEASPVSNL 710
+ S ++T + T A+L + +I ST+ S+A+ + LP S AS +
Sbjct: 1490 IHSQQSTPFPDSPGFTHTVLPATLTTTDIGQESTAFHSSSDATGTTPLPARSTASDLVGE 1549
Query: 711 PLTSETSPMSDLPLTSETSSVSSMLLTSETTFVSSLPLPSETSPISNSSINERMA 765
P T SP SS +S L TTF +S PS TS I ++ E +A
Sbjct: 1550 PTTFYISPSPTYTTLFPASSSTSGLTEESTTFHTS---PSFTSTIVSTESLETLA 1601
>gi|52485606 formin-like 2 [Homo sapiens]
Length = 1092
Score = 66.2 bits (160), Expect = 3e-10
Identities = 47/163 (28%), Positives = 74/163 (45%), Gaps = 12/163 (7%)
Query: 1992 PNMPMKEGDEVGGTAHTMPNKALVHPPPPPPPPPPPPLALPPPPPPPPPLPPPLPNAEVP 2051
P P+ + T P V PP PPPPPPPPP PPPPPPPPPLP P VP
Sbjct: 529 PPPPLPPSSDTPETVQNGP----VTPPMPPPPPPPPPPPPPPPPPPPPPLPGPAAET-VP 583
Query: 2052 SDQKQPPV----TMETTKRLSWPQSTGICSNIKSEPL--SFEEGLSSSCELGMKQVSYDQ 2105
+ PP+ + T + ++G+ + +P+ F + + L Q++
Sbjct: 584 APPLAPPLPSAPPLPGTSSPTVVFNSGLAAVKIKKPIKTKFRMPVFNWVALKPNQINGTV 643
Query: 2106 -NEMKEQLKAFALKSADFSSYLLSEPQKPFTQLAAQKMQVQQQ 2147
NE+ ++ L +F ++ Q P L++ K ++ Q+
Sbjct: 644 FNEIDDERILEDLNVDEFEEIFKTKAQGPAIDLSSSKQKIPQK 686
>gi|11386183 WAS protein family, member 2 [Homo sapiens]
Length = 498
Score = 65.9 bits (159), Expect = 4e-10
Identities = 39/89 (43%), Positives = 44/89 (49%), Gaps = 16/89 (17%)
Query: 2010 PNKALVHPPPPPPPP-------PPPPL------ALPPPPPPPPPLPPPLPNAEVPSDQKQ 2056
P+ PPPPPPPP PPPPL A PPPPPPPPP PPP P
Sbjct: 357 PHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPGPPPPPFTGADGQPAI 416
Query: 2057 PPVTMETTKRLSWPQSTGICSNIKSEPLS 2085
PP +TTK S S S+ +S+ LS
Sbjct: 417 PPPLSDTTKPKS---SLPAVSDARSDLLS 442
Score = 57.4 bits (137), Expect = 2e-07
Identities = 26/54 (48%), Positives = 29/54 (53%), Gaps = 12/54 (22%)
Query: 2017 PPPPPPPPPPPPLALPPPPP---------PPPPLP---PPLPNAEVPSDQKQPP 2058
PPP PPPPPPP + +PPPPP PPPP P PP P+ P PP
Sbjct: 318 PPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPPPP 371
Score = 50.4 bits (119), Expect = 2e-05
Identities = 26/52 (50%), Positives = 26/52 (50%), Gaps = 10/52 (19%)
Query: 2017 PPPPPPP--PPPPPLALPPPPPPPPPL------PPPL--PNAEVPSDQKQPP 2058
PPPP PP PP P A PPPPPPPP PPPL P P PP
Sbjct: 347 PPPPSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPP 398
Score = 48.1 bits (113), Expect = 9e-05
Identities = 24/53 (45%), Positives = 27/53 (50%), Gaps = 12/53 (22%)
Query: 2008 TMPNKALVHPPPPPPPPPPPPLALPPPPPPPPP---------LPPPLPNAEVP 2051
T+P L P PPPPPPP PPP PPPPP +PPPL + P
Sbjct: 377 TLPPPPLSQPTGGAPPPPPPP---PPPGPPPPPFTGADGQPAIPPPLSDTTKP 426
Score = 47.4 bits (111), Expect = 2e-04
Identities = 25/51 (49%), Positives = 26/51 (50%), Gaps = 8/51 (15%)
Query: 2016 HPPPPPP---PPPP-----PPLALPPPPPPPPPLPPPLPNAEVPSDQKQPP 2058
HPPP PP PP P PP A PPPPPP +PPP P S PP
Sbjct: 299 HPPPAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPP 349
Score = 44.7 bits (104), Expect = 0.001
Identities = 21/43 (48%), Positives = 22/43 (51%), Gaps = 3/43 (6%)
Query: 2020 PPPPPPPPPLALPPPPPP---PPPLPPPLPNAEVPSDQKQPPV 2059
P PPP PPL PP P P PPP PPP P + PPV
Sbjct: 297 PSHPPPAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPV 339
Score = 43.1 bits (100), Expect = 0.003
Identities = 27/68 (39%), Positives = 30/68 (44%), Gaps = 15/68 (22%)
Query: 2006 AHTMPNKALVHPPPPPPPPPPPPLALPPP------PPPPPPL--------PPPLPNAEVP 2051
+H P L PP P P PPP PPP PPPPPP+ PPP P + P
Sbjct: 298 SHPPPAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPP 357
Query: 2052 -SDQKQPP 2058
D PP
Sbjct: 358 HPDFAAPP 365
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.124 0.347
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 97,058,658
Number of Sequences: 37866
Number of extensions: 5392127
Number of successful extensions: 98879
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 974
Number of HSP's successfully gapped in prelim test: 991
Number of HSP's that attempted gapping in prelim test: 40204
Number of HSP's gapped (non-prelim): 27686
length of query: 2248
length of database: 18,247,518
effective HSP length: 118
effective length of query: 2130
effective length of database: 13,779,330
effective search space: 29349972900
effective search space used: 29349972900
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.