Guide to the Human Genome
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Search of human proteins with 149588534

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|149588534 ataxin 7-like 3 isoform b [Homo sapiens]
         (347 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|149588534 ataxin 7-like 3 isoform b [Homo sapiens]                 711   0.0  
gi|149588870 ataxin 7-like 3 isoform a [Homo sapiens]                 704   0.0  
gi|210147443 hypothetical protein LOC552889 [Homo sapiens]             99   7e-21
gi|163937854 ataxin 7-like 1 isoform 1 [Homo sapiens]                  47   3e-05
gi|211971080 ataxin 7-like 1 isoform 3 [Homo sapiens]                  47   3e-05
gi|93277115 ataxin 7-like 2 [Homo sapiens]                             42   8e-04
gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sap...    40   0.002
gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sap...    40   0.002
gi|189491742 ataxin 7 isoform b [Homo sapiens]                         40   0.004
gi|4506797 ataxin 7 isoform a [Homo sapiens]                           40   0.004
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    39   0.005
gi|42560244 peptidylprolyl isomerase G [Homo sapiens]                  37   0.026
gi|209977084 REST corepressor 3 isoform c [Homo sapiens]               37   0.034
gi|209977082 REST corepressor 3 isoform b [Homo sapiens]               37   0.034
gi|209977080 REST corepressor 3 isoform a [Homo sapiens]               37   0.034
gi|8922733 REST corepressor 3 isoform d [Homo sapiens]                 37   0.034
gi|42734375 ankyrin repeat and sterile alpha motif domain contai...    37   0.034
gi|50409738 SRp25 nuclear protein isoform 3 [Homo sapiens]             36   0.045
gi|203097003 Rho GTPase activating protein 21 [Homo sapiens]           36   0.058
gi|27734775 hypothetical protein LOC286499 [Homo sapiens]              35   0.076
gi|41055989 M-phase phosphoprotein 8 [Homo sapiens]                    35   0.13 
gi|118600981 jumonji domain containing 1C isoform a [Homo sapiens]     35   0.13 
gi|68342036 jumonji domain containing 1C isoform b [Homo sapiens]      35   0.13 
gi|166706868 synaptopodin 2-like isoform a [Homo sapiens]              35   0.13 
gi|52426743 cisplatin resistance-associated overexpressed protei...    35   0.13 
gi|19923485 cisplatin resistance-associated overexpressed protei...    35   0.13 
gi|50301232 synaptopodin 2-like isoform b [Homo sapiens]               35   0.13 
gi|42718015 retinoblastoma binding protein 8 isoform a [Homo sap...    34   0.22 
gi|4506441 retinoblastoma binding protein 8 isoform a [Homo sapi...    34   0.22 
gi|110431370 espin [Homo sapiens]                                      33   0.29 

>gi|149588534 ataxin 7-like 3 isoform b [Homo sapiens]
          Length = 347

 Score =  711 bits (1836), Expect = 0.0
 Identities = 347/347 (100%), Positives = 347/347 (100%)

Query: 1   MKMEEMSLSGLDNSKLEAIAQEIYADLVEDSCLGFCFEVHRAVKCGYFFLDDTDPDSMKD 60
           MKMEEMSLSGLDNSKLEAIAQEIYADLVEDSCLGFCFEVHRAVKCGYFFLDDTDPDSMKD
Sbjct: 1   MKMEEMSLSGLDNSKLEAIAQEIYADLVEDSCLGFCFEVHRAVKCGYFFLDDTDPDSMKD 60

Query: 61  FEIVDQPGLDIFGQVFNQWKSKECVCPNCSRSIAASRFAPHLEKCLGMGRNSSRIANRRI 120
           FEIVDQPGLDIFGQVFNQWKSKECVCPNCSRSIAASRFAPHLEKCLGMGRNSSRIANRRI
Sbjct: 61  FEIVDQPGLDIFGQVFNQWKSKECVCPNCSRSIAASRFAPHLEKCLGMGRNSSRIANRRI 120

Query: 121 ANSNNMNKSESDQEDNDDINDNDWSYGSEKKAKKRKSDKNPNSPRRSKSLKHKNGELSNS 180
           ANSNNMNKSESDQEDNDDINDNDWSYGSEKKAKKRKSDKNPNSPRRSKSLKHKNGELSNS
Sbjct: 121 ANSNNMNKSESDQEDNDDINDNDWSYGSEKKAKKRKSDKNPNSPRRSKSLKHKNGELSNS 180

Query: 181 DPFKYNNSTGISYETLGPEELRSLLTTQCGVISEHTKKMCTRSLRCPQHTDEQRRTVRIY 240
           DPFKYNNSTGISYETLGPEELRSLLTTQCGVISEHTKKMCTRSLRCPQHTDEQRRTVRIY
Sbjct: 181 DPFKYNNSTGISYETLGPEELRSLLTTQCGVISEHTKKMCTRSLRCPQHTDEQRRTVRIY 240

Query: 241 FLGPSAVLPEVESSLDNDSFDMTDSQALISRLQWDGSSDLSPSDSGSSKTSENQGWGLGT 300
           FLGPSAVLPEVESSLDNDSFDMTDSQALISRLQWDGSSDLSPSDSGSSKTSENQGWGLGT
Sbjct: 241 FLGPSAVLPEVESSLDNDSFDMTDSQALISRLQWDGSSDLSPSDSGSSKTSENQGWGLGT 300

Query: 301 NSSESRKTKKKKSHLSLVGTASGLGSNKKKKPKPPAPPTPSIYDDIN 347
           NSSESRKTKKKKSHLSLVGTASGLGSNKKKKPKPPAPPTPSIYDDIN
Sbjct: 301 NSSESRKTKKKKSHLSLVGTASGLGSNKKKKPKPPAPPTPSIYDDIN 347


>gi|149588870 ataxin 7-like 3 isoform a [Homo sapiens]
          Length = 354

 Score =  704 bits (1818), Expect = 0.0
 Identities = 347/354 (98%), Positives = 347/354 (98%), Gaps = 7/354 (1%)

Query: 1   MKMEEMSLSGLDNSKLEAIAQEIYADLVEDSCLGFCFEVHRAVKCGYFFLDDTDPDSMKD 60
           MKMEEMSLSGLDNSKLEAIAQEIYADLVEDSCLGFCFEVHRAVKCGYFFLDDTDPDSMKD
Sbjct: 1   MKMEEMSLSGLDNSKLEAIAQEIYADLVEDSCLGFCFEVHRAVKCGYFFLDDTDPDSMKD 60

Query: 61  FEIVDQPGLDIFGQVFNQWKSKECVCPNCSRSIAASRFAPHLEKCLGMGRNSSRIANRRI 120
           FEIVDQPGLDIFGQVFNQWKSKECVCPNCSRSIAASRFAPHLEKCLGMGRNSSRIANRRI
Sbjct: 61  FEIVDQPGLDIFGQVFNQWKSKECVCPNCSRSIAASRFAPHLEKCLGMGRNSSRIANRRI 120

Query: 121 ANSNNMNKSESDQEDNDDINDNDWSYGSEKKAKKRKSDK-------NPNSPRRSKSLKHK 173
           ANSNNMNKSESDQEDNDDINDNDWSYGSEKKAKKRKSDK       NPNSPRRSKSLKHK
Sbjct: 121 ANSNNMNKSESDQEDNDDINDNDWSYGSEKKAKKRKSDKLWYLPFQNPNSPRRSKSLKHK 180

Query: 174 NGELSNSDPFKYNNSTGISYETLGPEELRSLLTTQCGVISEHTKKMCTRSLRCPQHTDEQ 233
           NGELSNSDPFKYNNSTGISYETLGPEELRSLLTTQCGVISEHTKKMCTRSLRCPQHTDEQ
Sbjct: 181 NGELSNSDPFKYNNSTGISYETLGPEELRSLLTTQCGVISEHTKKMCTRSLRCPQHTDEQ 240

Query: 234 RRTVRIYFLGPSAVLPEVESSLDNDSFDMTDSQALISRLQWDGSSDLSPSDSGSSKTSEN 293
           RRTVRIYFLGPSAVLPEVESSLDNDSFDMTDSQALISRLQWDGSSDLSPSDSGSSKTSEN
Sbjct: 241 RRTVRIYFLGPSAVLPEVESSLDNDSFDMTDSQALISRLQWDGSSDLSPSDSGSSKTSEN 300

Query: 294 QGWGLGTNSSESRKTKKKKSHLSLVGTASGLGSNKKKKPKPPAPPTPSIYDDIN 347
           QGWGLGTNSSESRKTKKKKSHLSLVGTASGLGSNKKKKPKPPAPPTPSIYDDIN
Sbjct: 301 QGWGLGTNSSESRKTKKKKSHLSLVGTASGLGSNKKKKPKPPAPPTPSIYDDIN 354


>gi|210147443 hypothetical protein LOC552889 [Homo sapiens]
          Length = 97

 Score = 98.6 bits (244), Expect = 7e-21
 Identities = 45/61 (73%), Positives = 53/61 (86%)

Query: 3  MEEMSLSGLDNSKLEAIAQEIYADLVEDSCLGFCFEVHRAVKCGYFFLDDTDPDSMKDFE 62
          MEE+SL+ LD +KLEAIAQEIY DL+EDSCLGFCFEVHRAVKCGYF+L+  +  S+KDF 
Sbjct: 1  MEEISLANLDTNKLEAIAQEIYVDLIEDSCLGFCFEVHRAVKCGYFYLEFAETGSVKDFG 60

Query: 63 I 63
          I
Sbjct: 61 I 61


>gi|163937854 ataxin 7-like 1 isoform 1 [Homo sapiens]
          Length = 861

 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 43/176 (24%), Positives = 76/176 (43%), Gaps = 27/176 (15%)

Query: 171 KHKNGELSNSDPFKYNNSTGISYETLGPEELRSLLTTQCGVISEHTKKMCTRSLRCPQHT 230
           KH+NG  +++ P++      +S     P +        CGV+   TKK CTRSL C  H+
Sbjct: 271 KHQNGTKNSNKPYRR-----LSEREFDPNK-------HCGVLDPETKKPCTRSLTCKTHS 318

Query: 231 DEQRRTVRIYFLGPSAVLPEVESSLDNDSFDMTDSQALISRLQWDGSSDLSPSDSGSSKT 290
              RR V         +L E ++   +   ++ D + L++      + ++ PS SG ++ 
Sbjct: 319 LSHRRAVPGRKKQFDLLLAEHKAK--SREKEVKDKEHLLT-----STREILPSQSGPAQD 371

Query: 291 S---ENQGWGLGTNSSESRKTKKKKSHLSLVGTASGLGSNKKKK-----PKPPAPP 338
           S    +   G     +   K++   S L    +A+ + S+         P+PP PP
Sbjct: 372 SLLGSSGSSGPEPKVASPAKSRPPNSVLPRPSSANSISSSTSSNHSGHTPEPPLPP 427


>gi|211971080 ataxin 7-like 1 isoform 3 [Homo sapiens]
          Length = 738

 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 43/176 (24%), Positives = 76/176 (43%), Gaps = 27/176 (15%)

Query: 171 KHKNGELSNSDPFKYNNSTGISYETLGPEELRSLLTTQCGVISEHTKKMCTRSLRCPQHT 230
           KH+NG  +++ P++      +S     P +        CGV+   TKK CTRSL C  H+
Sbjct: 147 KHQNGTKNSNKPYRR-----LSEREFDPNK-------HCGVLDPETKKPCTRSLTCKTHS 194

Query: 231 DEQRRTVRIYFLGPSAVLPEVESSLDNDSFDMTDSQALISRLQWDGSSDLSPSDSGSSKT 290
              RR V         +L E ++   +   ++ D + L++      + ++ PS SG ++ 
Sbjct: 195 LSHRRAVPGRKKQFDLLLAEHKAK--SREKEVKDKEHLLT-----STREILPSQSGPAQD 247

Query: 291 S---ENQGWGLGTNSSESRKTKKKKSHLSLVGTASGLGSNKKKK-----PKPPAPP 338
           S    +   G     +   K++   S L    +A+ + S+         P+PP PP
Sbjct: 248 SLLGSSGSSGPEPKVASPAKSRPPNSVLPRPSSANSISSSTSSNHSGHTPEPPLPP 303


>gi|93277115 ataxin 7-like 2 [Homo sapiens]
          Length = 722

 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 19/34 (55%), Positives = 23/34 (67%)

Query: 205 LTTQCGVISEHTKKMCTRSLRCPQHTDEQRRTVR 238
           L  QCGVI+  TKK+CTR L C  H+  QRR V+
Sbjct: 239 LNRQCGVINPETKKICTRLLTCKIHSVHQRREVQ 272


>gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sapiens]
          Length = 1758

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 56/216 (25%), Positives = 85/216 (39%), Gaps = 37/216 (17%)

Query: 123  SNNMNKSESDQEDNDDINDNDWSYGSEKKAKKRKS-DKNPNSPRRSKSLKHKNGELSNSD 181
            + +  KS S    +   +D+  +Y +++  ++ KS DKNP   R    L+ +N + S+ +
Sbjct: 1492 TGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVDKNPCKDREKHVLEARNNKESSGN 1551

Query: 182  PFKYNNSTGISYETLGPEELRSLLTTQCGVISEHT---KKMCTRSLRCPQHTDEQRRTVR 238
               Y          L P E +       G I + T   K   + S R    +D  R T  
Sbjct: 1552 KLLY---------ILNPPETQVEKEQITGQIDKSTVKPKPQLSHSSRLS--SDLTRETDE 1600

Query: 239  IYFL-------GPSAVLPEVESSLDNDSFDMTDS---------------QALISRLQWDG 276
              F          S V  + E S  N S D+ D                Q  ISR Q   
Sbjct: 1601 AAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAKESLDTAAVVQVGISRNQSHS 1660

Query: 277  SSDLSPSDSGSSKTSENQGWGLGTNSSESRKTKKKK 312
            S  +SPS S S   S+ +      +S+ES+ +KKKK
Sbjct: 1661 SPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKK 1696



 Score = 29.3 bits (64), Expect = 5.4
 Identities = 22/82 (26%), Positives = 33/82 (40%)

Query: 108  MGRNSSRIANRRIANSNNMNKSESDQEDNDDINDNDWSYGSEKKAKKRKSDKNPNSPRRS 167
            +G+ +S I N     SN +   E + E ++ I         E    + KS KN  S  + 
Sbjct: 1308 VGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKDVSHEIIQHEVKSSKNSASSEKG 1367

Query: 168  KSLKHKNGELSNSDPFKYNNST 189
            K+       L   +P K  NST
Sbjct: 1368 KTKDRDYSVLEKENPEKRKNST 1389



 Score = 29.3 bits (64), Expect = 5.4
 Identities = 18/72 (25%), Positives = 34/72 (47%), Gaps = 1/72 (1%)

Query: 106  LGMGRNSSRIANRRIANSNNMNKSESDQEDNDDINDNDWSYGSEKKAKKRKSDKNPNSPR 165
            +G+ RN S  ++  ++ S + + S S    +     +  S  S+KK KK++  K+    +
Sbjct: 1651 VGISRNQSH-SSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKK 1709

Query: 166  RSKSLKHKNGEL 177
              K  KH   E+
Sbjct: 1710 HKKHKKHAGTEV 1721


>gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sapiens]
          Length = 1792

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 56/216 (25%), Positives = 85/216 (39%), Gaps = 37/216 (17%)

Query: 123  SNNMNKSESDQEDNDDINDNDWSYGSEKKAKKRKS-DKNPNSPRRSKSLKHKNGELSNSD 181
            + +  KS S    +   +D+  +Y +++  ++ KS DKNP   R    L+ +N + S+ +
Sbjct: 1526 TGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVDKNPCKDREKHVLEARNNKESSGN 1585

Query: 182  PFKYNNSTGISYETLGPEELRSLLTTQCGVISEHT---KKMCTRSLRCPQHTDEQRRTVR 238
               Y          L P E +       G I + T   K   + S R    +D  R T  
Sbjct: 1586 KLLY---------ILNPPETQVEKEQITGQIDKSTVKPKPQLSHSSRLS--SDLTRETDE 1634

Query: 239  IYFL-------GPSAVLPEVESSLDNDSFDMTDS---------------QALISRLQWDG 276
              F          S V  + E S  N S D+ D                Q  ISR Q   
Sbjct: 1635 AAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAKESLDTAAVVQVGISRNQSHS 1694

Query: 277  SSDLSPSDSGSSKTSENQGWGLGTNSSESRKTKKKK 312
            S  +SPS S S   S+ +      +S+ES+ +KKKK
Sbjct: 1695 SPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKK 1730



 Score = 29.3 bits (64), Expect = 5.4
 Identities = 22/82 (26%), Positives = 33/82 (40%)

Query: 108  MGRNSSRIANRRIANSNNMNKSESDQEDNDDINDNDWSYGSEKKAKKRKSDKNPNSPRRS 167
            +G+ +S I N     SN +   E + E ++ I         E    + KS KN  S  + 
Sbjct: 1342 VGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKDVSHEIIQHEVKSSKNSASSEKG 1401

Query: 168  KSLKHKNGELSNSDPFKYNNST 189
            K+       L   +P K  NST
Sbjct: 1402 KTKDRDYSVLEKENPEKRKNST 1423



 Score = 29.3 bits (64), Expect = 5.4
 Identities = 18/72 (25%), Positives = 34/72 (47%), Gaps = 1/72 (1%)

Query: 106  LGMGRNSSRIANRRIANSNNMNKSESDQEDNDDINDNDWSYGSEKKAKKRKSDKNPNSPR 165
            +G+ RN S  ++  ++ S + + S S    +     +  S  S+KK KK++  K+    +
Sbjct: 1685 VGISRNQSH-SSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKK 1743

Query: 166  RSKSLKHKNGEL 177
              K  KH   E+
Sbjct: 1744 HKKHKKHAGTEV 1755


>gi|189491742 ataxin 7 isoform b [Homo sapiens]
          Length = 945

 Score = 39.7 bits (91), Expect = 0.004
 Identities = 40/142 (28%), Positives = 59/142 (41%), Gaps = 14/142 (9%)

Query: 209 CGVISEHTKKMCTRSLRCPQHTDEQRRTVRIYFLGPSAVLPEVES-SLDNDSFDMTDSQA 267
           CGVI   TKK CTRSL C  H+  QRR V+        +L E ++ + + +     DSQ 
Sbjct: 347 CGVIDLDTKKPCTRSLTCKTHSLTQRRAVQGRRKRFDVLLAEHKNKTREKELIRHPDSQQ 406

Query: 268 LISRLQWDGSSDLSPSDSGSSKTSENQGWGLGTNSSESRKTKKKKSHLSLV----GTASG 323
               L+     D  P+   +S+       G+  + S+     K K H   +    G  + 
Sbjct: 407 PPQPLR-----DPHPAPPRTSQEPHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGCPAQ 461

Query: 324 LGSNKKKKPKP----PAPPTPS 341
            G +    P P    P PP P+
Sbjct: 462 QGGSAPIDPPPVHESPHPPLPA 483


>gi|4506797 ataxin 7 isoform a [Homo sapiens]
          Length = 892

 Score = 39.7 bits (91), Expect = 0.004
 Identities = 40/142 (28%), Positives = 59/142 (41%), Gaps = 14/142 (9%)

Query: 209 CGVISEHTKKMCTRSLRCPQHTDEQRRTVRIYFLGPSAVLPEVES-SLDNDSFDMTDSQA 267
           CGVI   TKK CTRSL C  H+  QRR V+        +L E ++ + + +     DSQ 
Sbjct: 347 CGVIDLDTKKPCTRSLTCKTHSLTQRRAVQGRRKRFDVLLAEHKNKTREKELIRHPDSQQ 406

Query: 268 LISRLQWDGSSDLSPSDSGSSKTSENQGWGLGTNSSESRKTKKKKSHLSLV----GTASG 323
               L+     D  P+   +S+       G+  + S+     K K H   +    G  + 
Sbjct: 407 PPQPLR-----DPHPAPPRTSQEPHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGCPAQ 461

Query: 324 LGSNKKKKPKP----PAPPTPS 341
            G +    P P    P PP P+
Sbjct: 462 QGGSAPIDPPPVHESPHPPLPA 483


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 39.3 bits (90), Expect = 0.005
 Identities = 42/185 (22%), Positives = 76/185 (41%), Gaps = 25/185 (13%)

Query: 122 NSNNMNKSES-DQEDNDDINDNDWSYGSEKKAKKRKSDKNPNSPRRSKSLKHKNGELSNS 180
           +S++ N S+S D  D+ D +D+  S  S+  + K +SD + +  +   S  + +    NS
Sbjct: 595 SSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNS 654

Query: 181 DPFKYNNSTGISYETLGPEELRSLLTTQCGVISEHTKKMCTRSLRCPQHTDEQRRTVRIY 240
           D    +NS+  S  +   +   S  ++     S+ +    + +                 
Sbjct: 655 DSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSN----------------- 697

Query: 241 FLGPSAVLPEVESSLDNDSFDMTDSQALISRLQWDGSSDLSPSDSGSSKTSENQGWGLGT 300
               S+   +   S D+DS D +DS    S    D  S  S   S SS +S++      +
Sbjct: 698 ----SSESSDSSDSSDSDSSDSSDSSNSNSS---DSDSSNSSDSSDSSNSSDSSDSSDSS 750

Query: 301 NSSES 305
           NSS+S
Sbjct: 751 NSSDS 755



 Score = 38.9 bits (89), Expect = 0.007
 Identities = 44/208 (21%), Positives = 78/208 (37%), Gaps = 13/208 (6%)

Query: 107 GMGRNSSRIANRRIANSNNMNKSESDQEDNDDINDNDWSYGSEKKAKKRKSDKNPNSPRR 166
           G G N +   ++  +     + S+SD  D+ + +D+  S  S+       SD + +    
Sbjct: 528 GNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDS 587

Query: 167 SKSLKHKNGELSNSDPFKYNNSTGISYETLGPEELRSLLTTQCGVISEHTKKMCTRSLRC 226
           S S    + + SNS     ++ +  S ++    + +S  +      S+   K  +     
Sbjct: 588 SDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNS 647

Query: 227 PQHTDEQRRTVRIYFLGPSAVLPEVESSLDNDSFDMTDSQALISRLQWDGSSDLS-PSDS 285
              +D             S       SS  +DS D +DS    S      SSD S  SDS
Sbjct: 648 SDSSDN------------SDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDS 695

Query: 286 GSSKTSENQGWGLGTNSSESRKTKKKKS 313
            +S  S +      ++SS+S  +    S
Sbjct: 696 SNSSESSDSSDSSDSDSSDSSDSSNSNS 723



 Score = 38.1 bits (87), Expect = 0.012
 Identities = 43/205 (20%), Positives = 82/205 (40%), Gaps = 18/205 (8%)

Query: 111 NSSRIANRRIANSNNMNKSESDQEDNDDINDN-DWSYGSEKKAKKRKSDKNPNSPRRSKS 169
           +SS  +N   ++ ++ + + SD  D+ D +D+ D S  S+       SD + +S     S
Sbjct: 745 DSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSS 804

Query: 170 LKHKNGELSNSDPFKYNNSTGISYETLGPEELRSLLTTQCGVISEHTKKMCTRSLRCPQH 229
               + + S+S     +NS+  S  +   +   S  ++     S+ +    +        
Sbjct: 805 NSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNS 864

Query: 230 TDEQRRTVRIYFLGPSAVLPEVESSLDNDSFDMTDSQALISRLQWDGSSDLSPSDSGSSK 289
           +D    +               +SS  +DS D +DS    S    D S   + SDS SS 
Sbjct: 865 SDSSDSS---------------DSSNSSDSSDSSDSNE--SSNSSDSSDSSNSSDSDSSD 907

Query: 290 TSENQGWGLGTNSSESRKTKKKKSH 314
           +S +      +NSS+S ++     +
Sbjct: 908 SSNSSDSSDSSNSSDSSESSNSSDN 932



 Score = 37.7 bits (86), Expect = 0.015
 Identities = 43/206 (20%), Positives = 76/206 (36%), Gaps = 2/206 (0%)

Query: 111  NSSRIANRRIANSNNMNKSESDQEDNDDINDNDWSYGSEKKAKKRKSDKNPNSPRRSKSL 170
            NSS  +N   ++ ++ +   SD  D+ D +D+D S  S+       SD + +S     S 
Sbjct: 822  NSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSD 881

Query: 171  KHKNGELSNSDPFKYNNSTGISYETLGPEELRSLLTTQCGVISEHTKKMCTRSLRCPQHT 230
               + E SNS     ++++  S  +       S  ++     SE +      +     ++
Sbjct: 882  SSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNS 941

Query: 231  DEQRRTVRIYFLGPSAVLPEVESSLDNDSFDMTDSQALISRLQWDGSSDLSPSDSGSSKT 290
             +   +        S+     +SS  +DS D   S +  S    D S     SDS  S  
Sbjct: 942  SDSSDSSDSSNSSDSS--NSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSD 999

Query: 291  SENQGWGLGTNSSESRKTKKKKSHLS 316
            S N      ++ S         S+ S
Sbjct: 1000 SSNSSDSSDSSDSSDSSNSSDSSNSS 1025



 Score = 37.0 bits (84), Expect = 0.026
 Identities = 42/221 (19%), Positives = 78/221 (35%), Gaps = 8/221 (3%)

Query: 111 NSSRIANRRIANSNNMNKSESDQEDNDDINDNDWSYGSEKKAKKRKSDKNPNSPRRSKSL 170
           NSS  ++   ++ ++ + + SD  D+ D +D+  S  S   +    S  + NS   S S 
Sbjct: 646 NSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSS 705

Query: 171 KHKNGELSNSDPFKYNNSTGISYETLGPEELRSLLTTQCGVISEHTKKMCTRSLRCPQHT 230
              + + S+S     +NS+             S  +              + S      +
Sbjct: 706 DSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSS 765

Query: 231 DEQRRTVRIYFLGPSAVLPEVESSLDNDSFDMTDSQALISRLQWDGSSDLSPSDSGSSKT 290
           D    +        S      +SS  +DS D ++S         D S+    SDS  S  
Sbjct: 766 DSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSS--------DSSNSSDSSDSSDSSD 817

Query: 291 SENQGWGLGTNSSESRKTKKKKSHLSLVGTASGLGSNKKKK 331
           S++      +NSS+S  +           ++ G  S+   +
Sbjct: 818 SDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNR 858



 Score = 36.6 bits (83), Expect = 0.034
 Identities = 43/191 (22%), Positives = 80/191 (41%), Gaps = 7/191 (3%)

Query: 121 ANSNNMNKSESDQEDNDDINDNDWSYGSEKKAKKRKSDKNPNSPRRSKSLKHKNGELSN- 179
           ++S++ + S+S    N + +D+D S  S+       SD + +S   + S    + + SN 
Sbjct: 705 SDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNS 764

Query: 180 ---SDPFKYNNSTGISYETLGPEELRSLLTTQCGVISEHTKKMCTRSLRCPQHTDEQRRT 236
              SD    ++S+  S  +   +   S  ++     S+ +    +        +D    +
Sbjct: 765 SDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSS 824

Query: 237 VRIYFLGPSAVLPEVESSLDNDSFDMTDSQALISRLQWDGSSDLSPS--DSGSSKTSENQ 294
                   S      +SS  +DS D +DS +  +R     SSD S S   S SS +S++ 
Sbjct: 825 DSSNSSDSSDSSNSSDSSDSSDSSDGSDSDS-SNRSDSSNSSDSSDSSDSSNSSDSSDSS 883

Query: 295 GWGLGTNSSES 305
                +NSS+S
Sbjct: 884 DSNESSNSSDS 894



 Score = 36.6 bits (83), Expect = 0.034
 Identities = 43/196 (21%), Positives = 75/196 (38%), Gaps = 4/196 (2%)

Query: 111 NSSRIANRRIANSNNMNKSESDQEDNDDINDNDWSYGSEKKAKKRKSDKNPNSPRRSKSL 170
           NSS  +N   ++ ++ +        +D  N +D S  S        SD +  S   S + 
Sbjct: 799 NSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNR 858

Query: 171 KHKNGELSNSDPFKYNNSTGISYETLGPEELRSLLTTQCGVISEHTKKMCTRSLRCPQHT 230
              +    +SD    +NS+  S  +   E   S  ++     S+      + S      +
Sbjct: 859 SDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNS---SDSS 915

Query: 231 DEQRRTVRIYFLGPSAVLPEVESSLDNDSFDMTD-SQALISRLQWDGSSDLSPSDSGSSK 289
           D    +        S      +SS  +DS D +D S +  S    D S+    SDS SS 
Sbjct: 916 DSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSD 975

Query: 290 TSENQGWGLGTNSSES 305
           +S++      ++SS+S
Sbjct: 976 SSDSSNSSDSSDSSDS 991



 Score = 35.8 bits (81), Expect = 0.058
 Identities = 42/196 (21%), Positives = 78/196 (39%), Gaps = 2/196 (1%)

Query: 111  NSSRIANRRIANSNNMNKSESDQEDNDDINDNDWSYGSEKKAKKRKSDKNPNSPRRSKSL 170
            N S  +N   ++ ++ + + SD  D+ D N++  S  S   +    SD + +S     S 
Sbjct: 857  NRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSD 916

Query: 171  KHKNGELSNSDPFKYN-NSTGISYETLGPEELRSLLTTQCGVISEHTKKMCTRSLRCPQH 229
               + + S S     N NS+  S  +   +   S  ++     S+ +    +        
Sbjct: 917  SSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDS 976

Query: 230  TDEQRRTVRIYFLGPSAVLPEVESSLDNDSFDMTDSQALISRLQWDGSSDLSPSDSGSSK 289
            +D    +        S      +SS  +DS D +DS    +      SSD S + S SS 
Sbjct: 977  SDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSD-SSNSSDSSD 1035

Query: 290  TSENQGWGLGTNSSES 305
            +S++      ++SS+S
Sbjct: 1036 SSDSSDSSDSSDSSDS 1051



 Score = 34.7 bits (78), Expect = 0.13
 Identities = 42/195 (21%), Positives = 80/195 (41%), Gaps = 6/195 (3%)

Query: 111  NSSRIANRRIANSNNMNKSESDQEDNDDINDNDWSYGSEKKAKKRKSDKNPNSPRRSKSL 170
            +SS  ++   ++ +N + + SD  D+ + +D+D S  S        S+ + +S   + S 
Sbjct: 872  DSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSD 931

Query: 171  KHKNGELSNSDPFKYNNSTGISYETLGPEELRSLLTTQCGVISEHTKKMCTRSLRCPQHT 230
               + + SNS     ++S+  S  +   +   S  ++     S+      + S      +
Sbjct: 932  NSNSSDSSNS-----SDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSS 986

Query: 231  DEQRRTVRIYFLGPSAVLPEVESSLDNDSFDMTDSQALISRLQWDGSSDLSPSDSGSSKT 290
            D    +        S      +SS  +DS + +DS           SSD S S S SS +
Sbjct: 987  DSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDS-SDSSDS 1045

Query: 291  SENQGWGLGTNSSES 305
            S++      +NSS+S
Sbjct: 1046 SDSSDSSDSSNSSDS 1060



 Score = 33.9 bits (76), Expect = 0.22
 Identities = 47/205 (22%), Positives = 77/205 (37%), Gaps = 23/205 (11%)

Query: 122  NSNNMNKSESDQEDNDDINDNDWSYGSEKKAKKRKSDKNPNSPRRSKSL----------- 170
            +S++ N S+SD  D+ + +D+  S  S   ++   S  N NS   S S            
Sbjct: 894  SSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNS 953

Query: 171  --KHKNGELSNSDPFKYNNSTGISYETLGPEELRSLLTTQCGVISEHTKKMCTRSLRCPQ 228
                 + + SNS     +NS+  S  +   +   S  ++     S+ +    + S     
Sbjct: 954  SDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNS--SDSSDSSD 1011

Query: 229  HTDEQRRTVRIYFLGPSAVLPEVESSLDNDSFDMTDSQALISRLQWDGSSDLSPS----- 283
             +D    +        S      +SS  +DS D +DS           SSD S S     
Sbjct: 1012 SSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSD 1071

Query: 284  ---DSGSSKTSENQGWGLGTNSSES 305
                S SS +SE+      +NSS+S
Sbjct: 1072 SSDSSDSSDSSESSDSSDSSNSSDS 1096



 Score = 32.7 bits (73), Expect = 0.49
 Identities = 39/185 (21%), Positives = 75/185 (40%), Gaps = 2/185 (1%)

Query: 121 ANSNNMNKSESDQEDNDDINDNDWSYGSEKKAKKRKSDKNPNSPRRSKSLKHKNGELSNS 180
           +++NN + + +    NDD + +D   G    +    SD + +S     S    +   S+S
Sbjct: 519 SDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSS 578

Query: 181 DPFKYNNSTGISYETLGPEELRSLLTTQCGVISEHTKKMCTRSLRCPQHTDEQRRTVRIY 240
           D    ++ +  S ++   +   S  ++     S+ +    +   +      E   +    
Sbjct: 579 DSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSS-DSD 637

Query: 241 FLGPSAVLPEVESSLDNDSFDMTDSQALISRLQWDGSSDLSPSDSGSSKTSENQGWGLGT 300
               S+     +SS ++DS D ++S           SSD S S S SS +S++      +
Sbjct: 638 SKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSD-SSSSSDSSNSSDSSDSSDSS 696

Query: 301 NSSES 305
           NSSES
Sbjct: 697 NSSES 701



 Score = 32.7 bits (73), Expect = 0.49
 Identities = 43/198 (21%), Positives = 82/198 (41%), Gaps = 5/198 (2%)

Query: 111  NSSRIANRRIANSNNMNKSESDQEDNDDINDNDWSYGSEKKAKKRKSDKNPNSPRRSKSL 170
            +SS  ++   +NS++ + S +  + +D  + +D S  S+       SD + +S   + S 
Sbjct: 961  DSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSD 1020

Query: 171  KHKNGELSNS-DPFKYNNSTGISYETLGPEELRSLLTTQCGVISEHTKKMCTRSLRCPQH 229
               + + SNS D    ++S+  S  +   +   S  ++     S+ +    + S      
Sbjct: 1021 SSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDS--SDSSDSSDS 1078

Query: 230  TDEQRRTVRIYFLGPSAVLPEVESSLDNDSFDMTDSQALISRLQWDGSSDLSPS--DSGS 287
            +D    +        S      +SS  +DS D +DS           SSD S S   S S
Sbjct: 1079 SDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDS 1138

Query: 288  SKTSENQGWGLGTNSSES 305
            S +S++      ++SS+S
Sbjct: 1139 SNSSDSSDSSESSDSSDS 1156



 Score = 32.3 bits (72), Expect = 0.64
 Identities = 37/187 (19%), Positives = 72/187 (38%), Gaps = 2/187 (1%)

Query: 121 ANSNNMNKSESDQEDNDDINDNDWSYGSEKKAKKRKSDKNPNSPRRSKSLKHKNGELSN- 179
           ++S+N + S    + ++    +D S  S+  +       N NS     S    + + SN 
Sbjct: 681 SDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNS 740

Query: 180 SDPFKYNNSTGISYETLGPEELRSLLTTQCGVISEHTKKMCTRSLRCPQHTDEQRRTVRI 239
           SD    ++S+  S  +   +   S  ++     S+ +    +       ++ +   +   
Sbjct: 741 SDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNS 800

Query: 240 YFLGPSAVLPEVESSLDNDSFDMTDSQALISRLQWDGSSDLS-PSDSGSSKTSENQGWGL 298
                S+   +   S D+DS + +DS           SSD S  SDS     S++     
Sbjct: 801 SDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSD 860

Query: 299 GTNSSES 305
            +NSS+S
Sbjct: 861 SSNSSDS 867



 Score = 32.0 bits (71), Expect = 0.84
 Identities = 41/187 (21%), Positives = 78/187 (41%), Gaps = 4/187 (2%)

Query: 122  NSNNMNKSESDQEDN--DDINDNDWSYGSEKKAKKRKSDKNPNSPRRSKSLKHKNGELSN 179
            +S++ N S+S +  N  D+ N +D S  S+       S+ + +S     S    + + ++
Sbjct: 914  SSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNS 973

Query: 180  SDPFKYNNSTGISYETLGPEELRSLLTTQCGVISEHTKKM-CTRSLRCPQHTDEQRRTVR 238
            SD    +NS+  S  +   +   S  ++     S+ +     + S      +D    +  
Sbjct: 974  SDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDS 1033

Query: 239  IYFLGPSAVLPEVESSLDNDSFDMTDSQALISRLQWDGSSDLSPSDSGSSKTSENQGWGL 298
                  S      +SS  +DS + +DS           SSD S S S SS++S++     
Sbjct: 1034 SDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDS-SDSSESSDSSDSSN 1092

Query: 299  GTNSSES 305
             ++SS+S
Sbjct: 1093 SSDSSDS 1099



 Score = 30.8 bits (68), Expect = 1.9
 Identities = 43/195 (22%), Positives = 78/195 (40%), Gaps = 10/195 (5%)

Query: 111  NSSRIANRRIANSNNMNKSESDQEDNDDINDNDWSYGSEKKAKKRKSDKNPNSPRRSKSL 170
            NSS  +N   +++++ +   SD  D+ D +D+  S  S   +    S  + +S   S S 
Sbjct: 1017 NSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSS 1076

Query: 171  KHKNGELSNSDPFKYNNSTGISYETLGPEELRSLLTTQCGVISEHTKKMCTRSLRCPQHT 230
               +   S SD    +NS+  S  +   +   S  ++     S+ +    +        +
Sbjct: 1077 DSSDSSES-SDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDS 1135

Query: 231  DEQRRTVRIYFLGPSAVLPEVESSLDNDSFDMTDSQALISRLQWDGSSDLSPSDSGSSKT 290
             +   +        S      ESS  +DS D +DS           SSD S + S SS +
Sbjct: 1136 SDSSNS--------SDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSD-SSNSSDSSDS 1186

Query: 291  SENQGWGLGTNSSES 305
            S++      ++SS+S
Sbjct: 1187 SDSSDSSDSSDSSDS 1201



 Score = 30.4 bits (67), Expect = 2.4
 Identities = 42/185 (22%), Positives = 72/185 (38%), Gaps = 11/185 (5%)

Query: 121  ANSNNMNKSESDQEDNDDINDNDWSYGSEKKAKKRKSDKNPNSPRRSKSLKHKNGELSNS 180
            ++S+N + S    + +D  N +D S  S+       SD + +S     S         +S
Sbjct: 998  SDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSS--------DSS 1049

Query: 181  DPFKYNNSTGISYETLGPEELRSLLTTQCGVISEHTKKMCTRSLRCPQHTDEQRRTVRIY 240
            D    +NS+  S  +   +   S  ++     SE +    + S      +D    +    
Sbjct: 1050 DSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDS--SDSSNSSDSSDSSDSSDSSD 1107

Query: 241  FLGPSAVLPEVESSLDNDSFDMTDSQALISRLQWDGSSDLSPSDSGSSKTSENQGWGLGT 300
                S      +SS  +DS D +DS           SSD S S S SS +S++      +
Sbjct: 1108 SSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSES-SDSSDSSDSSDSSDSS 1166

Query: 301  NSSES 305
            +SS+S
Sbjct: 1167 DSSDS 1171



 Score = 29.3 bits (64), Expect = 5.4
 Identities = 46/191 (24%), Positives = 77/191 (40%), Gaps = 8/191 (4%)

Query: 122  NSNNMNKSES-DQEDNDDINDNDWSYGSEKKAKKRKSDKNPNSPRRSKSLKHKNGELSN- 179
            +S++ N S+S D  D+ D +D+  S  S   ++   S  + NS   S S    +   S+ 
Sbjct: 1051 SSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSD 1110

Query: 180  ----SDPFKYNNSTGISYETLGPEELRSLLTTQCGVISEHTKKM-CTRSLRCPQHTDEQR 234
                SD    +NS+  S  +   +   S  ++     SE +     + S      +D   
Sbjct: 1111 SSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSD 1170

Query: 235  RTVRIYFLGPSAVLPEVESSLDNDSFDMTDSQALISRLQWDGSSDLSPSDSGSSKTSENQ 294
             +        S      +SS  +DS D +DS           SSD S S S SS +S++ 
Sbjct: 1171 SSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS-SDSSDSSDSS 1229

Query: 295  GWGLGTNSSES 305
                 ++SS+S
Sbjct: 1230 DSNESSDSSDS 1240



 Score = 28.9 bits (63), Expect = 7.1
 Identities = 20/62 (32%), Positives = 31/62 (50%), Gaps = 3/62 (4%)

Query: 121  ANSNNMNKSESDQEDNDDINDNDWSYGSEKKAKKRKSDKNPNSPRRSKSLK-HKNGELSN 179
            ++SN  + S    + +D  N +D S  S+  +    SD N  S  +SKS   + NG  S+
Sbjct: 1229 SDSNESSDSSDSSDSSDSSNSSDSSDSSD--SSDSTSDSNDESDSQSKSGNGNNNGSDSD 1286

Query: 180  SD 181
            SD
Sbjct: 1287 SD 1288



 Score = 28.5 bits (62), Expect = 9.3
 Identities = 43/208 (20%), Positives = 72/208 (34%), Gaps = 15/208 (7%)

Query: 121 ANSNNMNKSESDQEDNDDINDNDWSYGS-EKKAKKRKSDKNPNSPRRSKSLKHKNGELSN 179
           ++ +N N   + + DN+  +  D SY S E K     SD        S S    N   SN
Sbjct: 468 SDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSN 527

Query: 180 SDPFKYNNSTGISYETLGPEELRSLLTTQCGVISEHTKKMCTRSLRCPQHTDEQRRTVRI 239
            +    N+    S    G  +     ++     S+ +    + S      +D        
Sbjct: 528 GNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSD--- 584

Query: 240 YFLGPSAVLPEVESSLDNDSFDMTDSQALISRLQWDGSSDLSPSDSGSSKTSENQGWGLG 299
                S+   + +SS  ++S D +DS         D S     SDS  SK+  ++     
Sbjct: 585 ---SDSSDSSDSDSSDSSNSSDSSDSS--------DSSDSSDSSDSSDSKSDSSKSESDS 633

Query: 300 TNSSESRKTKKKKSHLSLVGTASGLGSN 327
           ++S     +    S  S   + S   SN
Sbjct: 634 SDSDSKSDSSDSNSSDSSDNSDSSDSSN 661


>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
          Length = 754

 Score = 37.0 bits (84), Expect = 0.026
 Identities = 24/82 (29%), Positives = 43/82 (52%), Gaps = 3/82 (3%)

Query: 121 ANSNNMNKSESDQEDNDDINDNDWSYGSEKKAKKRKSDKNPNSPRRSK-SLKHKNGELSN 179
           ++S++ + S SD + + D +D++ +  +E+K+KKRK     NS +  K   K K  + S 
Sbjct: 198 SSSSSDSDSSSDSQSSSDSSDSESA--TEEKSKKRKKKHRKNSRKHKKEKKKRKKSKKSA 255

Query: 180 SDPFKYNNSTGISYETLGPEEL 201
           S   +  N       T+ PEE+
Sbjct: 256 SSESEAENLEAQPQSTVRPEEI 277



 Score = 31.6 bits (70), Expect = 1.1
 Identities = 23/95 (24%), Positives = 42/95 (44%), Gaps = 1/95 (1%)

Query: 110 RNSSRIANRRIANSNNMNKSESDQEDNDDINDNDWSYGSEKKAKKR-KSDKNPNSPRRSK 168
           RN S   NR+      +   +S+ ++ D   +++     + K KKR KS     S  +SK
Sbjct: 410 RNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSK 469

Query: 169 SLKHKNGELSNSDPFKYNNSTGISYETLGPEELRS 203
           S +  +    N +    + S G  +E +  +E +S
Sbjct: 470 SKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQS 504



 Score = 31.2 bits (69), Expect = 1.4
 Identities = 23/86 (26%), Positives = 39/86 (45%), Gaps = 9/86 (10%)

Query: 253 SSLDNDSFDMTDSQALISRLQWDGSSDLSPSDSGSSKTSENQGWGLGTNSSESRKTKKKK 312
           SS  +DS   +DSQ+         SSD S S+S + + S+ +      NS + +K KKK+
Sbjct: 198 SSSSSDSDSSSDSQS---------SSDSSDSESATEEKSKKRKKKHRKNSRKHKKEKKKR 248

Query: 313 SHLSLVGTASGLGSNKKKKPKPPAPP 338
                  ++     N + +P+    P
Sbjct: 249 KKSKKSASSESEAENLEAQPQSTVRP 274


>gi|209977084 REST corepressor 3 isoform c [Homo sapiens]
          Length = 449

 Score = 36.6 bits (83), Expect = 0.034
 Identities = 19/64 (29%), Positives = 34/64 (53%), Gaps = 7/64 (10%)

Query: 118 RRIANSNNMNKSESDQEDNDDINDNDWSYGSEKKAKKRKSDKNPNSP-------RRSKSL 170
           R++AN +N   S+ D E+   ++ ND  Y  +K+AKK  + + P          R  +SL
Sbjct: 203 RKLANRHNQGDSDDDVEETHPMDGNDSDYDPKKEAKKEGNTEQPVQTSKIGLGRREYQSL 262

Query: 171 KHKN 174
           +H++
Sbjct: 263 QHRH 266


>gi|209977082 REST corepressor 3 isoform b [Homo sapiens]
          Length = 436

 Score = 36.6 bits (83), Expect = 0.034
 Identities = 19/64 (29%), Positives = 34/64 (53%), Gaps = 7/64 (10%)

Query: 118 RRIANSNNMNKSESDQEDNDDINDNDWSYGSEKKAKKRKSDKNPNSP-------RRSKSL 170
           R++AN +N   S+ D E+   ++ ND  Y  +K+AKK  + + P          R  +SL
Sbjct: 203 RKLANRHNQGDSDDDVEETHPMDGNDSDYDPKKEAKKEGNTEQPVQTSKIGLGRREYQSL 262

Query: 171 KHKN 174
           +H++
Sbjct: 263 QHRH 266


>gi|209977080 REST corepressor 3 isoform a [Homo sapiens]
          Length = 553

 Score = 36.6 bits (83), Expect = 0.034
 Identities = 19/64 (29%), Positives = 34/64 (53%), Gaps = 7/64 (10%)

Query: 118 RRIANSNNMNKSESDQEDNDDINDNDWSYGSEKKAKKRKSDKNPNSP-------RRSKSL 170
           R++AN +N   S+ D E+   ++ ND  Y  +K+AKK  + + P          R  +SL
Sbjct: 203 RKLANRHNQGDSDDDVEETHPMDGNDSDYDPKKEAKKEGNTEQPVQTSKIGLGRREYQSL 262

Query: 171 KHKN 174
           +H++
Sbjct: 263 QHRH 266


>gi|8922733 REST corepressor 3 isoform d [Homo sapiens]
          Length = 495

 Score = 36.6 bits (83), Expect = 0.034
 Identities = 19/64 (29%), Positives = 34/64 (53%), Gaps = 7/64 (10%)

Query: 118 RRIANSNNMNKSESDQEDNDDINDNDWSYGSEKKAKKRKSDKNPNSP-------RRSKSL 170
           R++AN +N   S+ D E+   ++ ND  Y  +K+AKK  + + P          R  +SL
Sbjct: 145 RKLANRHNQGDSDDDVEETHPMDGNDSDYDPKKEAKKEGNTEQPVQTSKIGLGRREYQSL 204

Query: 171 KHKN 174
           +H++
Sbjct: 205 QHRH 208


>gi|42734375 ankyrin repeat and sterile alpha motif domain
           containing 3 [Homo sapiens]
          Length = 656

 Score = 36.6 bits (83), Expect = 0.034
 Identities = 46/189 (24%), Positives = 82/189 (43%), Gaps = 24/189 (12%)

Query: 82  KECVCPNCSRSIAASRFAPHLEK---CLGMGRNSSRIANRRIANSNNMNKSESDQEDNDD 138
           ++   P   R + +S  +   E+   C  +G   S  ++  +A +  ++ SE+  E N+D
Sbjct: 316 RDVTSPINERDVESSSSSSSREEHAFCANLGPVQSSSSSEGLARAQGLS-SEASVESNED 374

Query: 139 INDNDWSYGSEKKAKKRKSDKNPNSPRRSKSLKHKNGELSNSDPFKYNNSTGISYETLGP 198
            +D+     + K+AK     KNP+S    ++   + G L+ S P     +    Y   GP
Sbjct: 375 -SDHACKSSARKQAKSYMKTKNPDSQWPPRAATDREGFLAESSP----QTQRAPYS--GP 427

Query: 199 EELRSLLTTQCGVISEHTKKMCTRSLRCPQHTDEQRRTVRIYFLGPSAVLPEVESSLDND 258
           ++L +LL  Q G         C + L   Q  +EQ   +RI+     + L E+  +L   
Sbjct: 428 QDLAALL-EQIG---------CLKYL---QVFEEQDVDLRIFLTLTESDLKEIGITLFGP 474

Query: 259 SFDMTDSQA 267
              MT + A
Sbjct: 475 KRKMTSAIA 483


>gi|50409738 SRp25 nuclear protein isoform 3 [Homo sapiens]
          Length = 352

 Score = 36.2 bits (82), Expect = 0.045
 Identities = 33/131 (25%), Positives = 54/131 (41%), Gaps = 6/131 (4%)

Query: 80  KSKECVCPNCSRSIAASRFAPHLEKCLGMGRNSSRIANRRIANSNNMNKSESDQEDNDDI 139
           KS++    NCS S +  R A       G    S + A RR  +S++ + S S    +   
Sbjct: 150 KSRKDTSRNCSASTSQGRKA---STAPGAEERSKQKARRRTRSSSSSSSSSSSSSSSSSS 206

Query: 140 NDNDWSYGSEKKAKKRKSDKNPNSPRRSKSLKHKNGELSNSDPFKYNNSTGIS--YETLG 197
           + +  S    KK  K K DK     ++ K LK K  E + +   +      +   + + G
Sbjct: 207 SSSSSSSDGRKKRGKYK-DKRRKKKKKRKKLKKKGKEKAEAQQVEALPGPSLDQWHRSAG 265

Query: 198 PEELRSLLTTQ 208
            EE   +LT +
Sbjct: 266 EEEDGPVLTDE 276


>gi|203097003 Rho GTPase activating protein 21 [Homo sapiens]
          Length = 1958

 Score = 35.8 bits (81), Expect = 0.058
 Identities = 29/100 (29%), Positives = 45/100 (45%), Gaps = 10/100 (10%)

Query: 243  GPSAVLPEVESSLDNDSFDMTDSQALISRLQWDGSSDLSPSDSGSSKTSENQG-WGLGTN 301
            G    L  V+     DS  + +   L++ +   G S    SDS +S +++++G WG G  
Sbjct: 1343 GAEEPLTTVQEESTVDSQPVPNIDHLLTNIGRTGVSPGDVSDSATSDSTKSKGSWGSG-- 1400

Query: 302  SSESRKTKKKKSHLSLVGTASGLGSNKKKKPKPPAPPTPS 341
                   K + S   LV +     S K+KKPK  A P+ S
Sbjct: 1401 -------KDQYSRELLVSSIFAAASRKRKKPKEKAQPSSS 1433


>gi|27734775 hypothetical protein LOC286499 [Homo sapiens]
          Length = 248

 Score = 35.4 bits (80), Expect = 0.076
 Identities = 28/102 (27%), Positives = 43/102 (42%), Gaps = 3/102 (2%)

Query: 103 EKCLGMGRNSSRIANRRIANSNNMNKSESDQEDNDDINDNDWSYGSEKKAKKRKSDKNPN 162
           EK L    +SS+   R+        +S S    +D  + +  S   EKK  KR+  K   
Sbjct: 78  EKLLSGNESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNR 137

Query: 163 SPRRSKSLKHKNGELSNSDPFKYNNSTGISYETLGPEELRSL 204
           S + S+S  H++   S     K   S     ET   +++RSL
Sbjct: 138 SYKSSQSSTHESESESKESVKKKKKSKD---ETEKEKDVRSL 176


>gi|41055989 M-phase phosphoprotein 8 [Homo sapiens]
          Length = 860

 Score = 34.7 bits (78), Expect = 0.13
 Identities = 54/229 (23%), Positives = 89/229 (38%), Gaps = 28/229 (12%)

Query: 118 RRIANSNNMNKSESDQEDNDDINDNDWSYGSEKKAKKRKSDKNPNSPRRSKSLKHKNGEL 177
           +R++ +N++ ++ SD +   +  + D S   +KK  +++ +K+P+  ++ K+   K  + 
Sbjct: 123 QRLSLNNDIFEANSDSDQQSETKE-DTSPKKKKKKLRQREEKSPDDLKKKKAKAGKLKDK 181

Query: 178 SNSDPFKYNNSTGISYETL-----GPEELRSLLTTQCGVISE-----HTKKMCTRSLRCP 227
           S  D      S      T        EEL+     +   + E       KK   R L+  
Sbjct: 182 SKPDLESSLESLVFDLRTKKRISEAKEELKESKKPKKDEVKETKELKKVKKGEIRDLKTK 241

Query: 228 QHTD--EQRRTVRIYFLGPSAVLPEVESSLDNDS-FDMTDSQALISRLQWDGSSDLSPSD 284
              D  E R+T +  F+       E ESS+ NDS F   DS+ L         SD     
Sbjct: 242 TREDPKENRKTKKEKFVESQV---ESESSVLNDSPFPEDDSEGL--------HSDSREEK 290

Query: 285 SGSSKTSENQGWGLGTNSSESRKTKKKKSHLSLVGTASGLGSNKKKKPK 333
             +    E  G  +G    E    K   S +S        G  KKK P+
Sbjct: 291 QNTKSARERAGQDMGL---EHGFEKPLDSAMSAEEDTDVRGRRKKKTPR 336


>gi|118600981 jumonji domain containing 1C isoform a [Homo sapiens]
          Length = 2540

 Score = 34.7 bits (78), Expect = 0.13
 Identities = 26/92 (28%), Positives = 41/92 (44%), Gaps = 8/92 (8%)

Query: 113 SRIANRRIANSNNMNKSESDQEDNDDIN------DN--DWSYGSEKKAKKRKSDKNPNSP 164
           SR  N +  N + MNK    +ED   +N      DN  D+S  S+ +   ++   N +  
Sbjct: 336 SRGENPKGKNKHLMNKRRKPEEDEKKLNMKRLRTDNVSDFSESSDSENSNKRIIDNSSEQ 395

Query: 165 RRSKSLKHKNGELSNSDPFKYNNSTGISYETL 196
           +    LK+KN    N +  K +N+     ETL
Sbjct: 396 KPENELKNKNTSKINGEEGKPHNNEKAGEETL 427


>gi|68342036 jumonji domain containing 1C isoform b [Homo sapiens]
          Length = 2303

 Score = 34.7 bits (78), Expect = 0.13
 Identities = 26/92 (28%), Positives = 41/92 (44%), Gaps = 8/92 (8%)

Query: 113 SRIANRRIANSNNMNKSESDQEDNDDIN------DN--DWSYGSEKKAKKRKSDKNPNSP 164
           SR  N +  N + MNK    +ED   +N      DN  D+S  S+ +   ++   N +  
Sbjct: 117 SRGENPKGKNKHLMNKRRKPEEDEKKLNMKRLRTDNVSDFSESSDSENSNKRIIDNSSEQ 176

Query: 165 RRSKSLKHKNGELSNSDPFKYNNSTGISYETL 196
           +    LK+KN    N +  K +N+     ETL
Sbjct: 177 KPENELKNKNTSKINGEEGKPHNNEKAGEETL 208


>gi|166706868 synaptopodin 2-like isoform a [Homo sapiens]
          Length = 977

 Score = 34.7 bits (78), Expect = 0.13
 Identities = 23/59 (38%), Positives = 35/59 (59%), Gaps = 4/59 (6%)

Query: 247 VLPEVESSLDNDSFDMTDSQALISRLQWDGSS-DLSPSDSGSSKTSENQGWGLGTNSSE 304
           V P  ES LD ++F  +D+++L ++  WD    D+  + +GS + SE QG GLG   SE
Sbjct: 327 VPPTSESELDEEAF--SDARSLTNQSDWDSPYLDMELARAGS-RASEGQGSGLGGQLSE 382


>gi|52426743 cisplatin resistance-associated overexpressed protein
           [Homo sapiens]
          Length = 432

 Score = 34.7 bits (78), Expect = 0.13
 Identities = 21/68 (30%), Positives = 34/68 (50%), Gaps = 3/68 (4%)

Query: 110 RNSSRIANRRIANSNNMNKSESDQEDNDDINDNDWSYG---SEKKAKKRKSDKNPNSPRR 166
           R+SSR ++RR + S +  +S S +       D   S     SE+K + R  D+  +  R 
Sbjct: 298 RHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRD 357

Query: 167 SKSLKHKN 174
            KS KH++
Sbjct: 358 RKSYKHRS 365


>gi|19923485 cisplatin resistance-associated overexpressed protein
           [Homo sapiens]
          Length = 432

 Score = 34.7 bits (78), Expect = 0.13
 Identities = 21/68 (30%), Positives = 34/68 (50%), Gaps = 3/68 (4%)

Query: 110 RNSSRIANRRIANSNNMNKSESDQEDNDDINDNDWSYG---SEKKAKKRKSDKNPNSPRR 166
           R+SSR ++RR + S +  +S S +       D   S     SE+K + R  D+  +  R 
Sbjct: 298 RHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRD 357

Query: 167 SKSLKHKN 174
            KS KH++
Sbjct: 358 RKSYKHRS 365


>gi|50301232 synaptopodin 2-like isoform b [Homo sapiens]
          Length = 753

 Score = 34.7 bits (78), Expect = 0.13
 Identities = 23/59 (38%), Positives = 35/59 (59%), Gaps = 4/59 (6%)

Query: 247 VLPEVESSLDNDSFDMTDSQALISRLQWDGSS-DLSPSDSGSSKTSENQGWGLGTNSSE 304
           V P  ES LD ++F  +D+++L ++  WD    D+  + +GS + SE QG GLG   SE
Sbjct: 103 VPPTSESELDEEAF--SDARSLTNQSDWDSPYLDMELARAGS-RASEGQGSGLGGQLSE 158


>gi|42718015 retinoblastoma binding protein 8 isoform a [Homo
           sapiens]
          Length = 897

 Score = 33.9 bits (76), Expect = 0.22
 Identities = 30/124 (24%), Positives = 52/124 (41%), Gaps = 4/124 (3%)

Query: 138 DINDNDWSYGSEKKAKKRKSDKNPNSPRRSKSLKHKN----GELSNSDPFKYNNSTGISY 193
           D+   D   GS+ K      D +      +  LK K     GE S+++  K N+S    +
Sbjct: 669 DVTVIDTKDGSQSKLGGETVDMDCTLVSETVLLKMKKQEQKGEKSSNEERKMNDSLEDMF 728

Query: 194 ETLGPEELRSLLTTQCGVISEHTKKMCTRSLRCPQHTDEQRRTVRIYFLGPSAVLPEVES 253
           +    EE  S L       ++  +++ T + +   H D+Q +  +  F+ P     E E+
Sbjct: 729 DRTTHEEYESCLADSFSQAADEEEELSTATKKLHTHGDKQDKVKQKAFVEPYFKGDERET 788

Query: 254 SLDN 257
           SL N
Sbjct: 789 SLQN 792


>gi|4506441 retinoblastoma binding protein 8 isoform a [Homo
           sapiens]
          Length = 897

 Score = 33.9 bits (76), Expect = 0.22
 Identities = 30/124 (24%), Positives = 52/124 (41%), Gaps = 4/124 (3%)

Query: 138 DINDNDWSYGSEKKAKKRKSDKNPNSPRRSKSLKHKN----GELSNSDPFKYNNSTGISY 193
           D+   D   GS+ K      D +      +  LK K     GE S+++  K N+S    +
Sbjct: 669 DVTVIDTKDGSQSKLGGETVDMDCTLVSETVLLKMKKQEQKGEKSSNEERKMNDSLEDMF 728

Query: 194 ETLGPEELRSLLTTQCGVISEHTKKMCTRSLRCPQHTDEQRRTVRIYFLGPSAVLPEVES 253
           +    EE  S L       ++  +++ T + +   H D+Q +  +  F+ P     E E+
Sbjct: 729 DRTTHEEYESCLADSFSQAADEEEELSTATKKLHTHGDKQDKVKQKAFVEPYFKGDERET 788

Query: 254 SLDN 257
           SL N
Sbjct: 789 SLQN 792


>gi|110431370 espin [Homo sapiens]
          Length = 854

 Score = 33.5 bits (75), Expect = 0.29
 Identities = 34/122 (27%), Positives = 52/122 (42%), Gaps = 10/122 (8%)

Query: 220 CTRSLRCPQHTDEQRRTVRIYFLGPSAVLPEVESSLDNDSFDMTDSQALISRLQWDGSSD 279
           CTR LR  ++   + R +      PSA   E+E+   +      ++   +  L +D SS 
Sbjct: 320 CTRYLRTVENLSVEHRVLS---RDPSA---ELEAKQPDSGMSSPNTTVSVQPLNFDLSSP 373

Query: 280 ---LSPSDSGSSKTSENQGWGLGTNSSESRKTKKKKSHLSLVGTASGLGSNKKKKPKPPA 336
              LS  DS SS  S  +G       S +R    + S++ ++    GL      KP PP 
Sbjct: 374 TSTLSNYDSCSSSHSSIKGQHPPCGLSSARAADIQ-SYMDMLNPELGLPRGTIGKPTPPP 432

Query: 337 PP 338
           PP
Sbjct: 433 PP 434


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.128    0.374 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,400,254
Number of Sequences: 37866
Number of extensions: 667464
Number of successful extensions: 4466
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 50
Number of HSP's successfully gapped in prelim test: 92
Number of HSP's that attempted gapping in prelim test: 3908
Number of HSP's gapped (non-prelim): 496
length of query: 347
length of database: 18,247,518
effective HSP length: 103
effective length of query: 244
effective length of database: 14,347,320
effective search space: 3500746080
effective search space used: 3500746080
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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