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Search of human proteins with 148612831
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|148612831 kinesin family member 18A [Homo sapiens]
(898 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|148612831 kinesin family member 18A [Homo sapiens] 1795 0.0
gi|122937289 kinesin family member 18B [Homo sapiens] 465 e-131
gi|156616271 kinesin family member 19 [Homo sapiens] 327 4e-89
gi|4758646 kinesin family member 3B [Homo sapiens] 264 3e-70
gi|46852174 kinesin family member 3A [Homo sapiens] 261 2e-69
gi|41393559 kinesin family member 1B isoform alpha [Homo sapiens] 241 2e-63
gi|41393563 kinesin family member 1B isoform b [Homo sapiens] 241 2e-63
gi|116686122 kinesin family member 4 [Homo sapiens] 241 2e-63
gi|46852172 kinesin family member 13B [Homo sapiens] 239 6e-63
gi|150010604 kinesin family member 4B [Homo sapiens] 239 8e-63
gi|41352705 kinesin family member 3C [Homo sapiens] 239 1e-62
gi|30794488 kinesin family member 27 [Homo sapiens] 237 3e-62
gi|19924175 axonal transport of synaptic vesicles [Homo sapiens] 234 2e-61
gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens] 234 4e-61
gi|83716024 kinesin family member 21B [Homo sapiens] 233 5e-61
gi|157738629 kinesin family member 13A isoform d [Homo sapiens] 233 6e-61
gi|157738627 kinesin family member 13A isoform c [Homo sapiens] 233 6e-61
gi|157738625 kinesin family member 13A isoform b [Homo sapiens] 233 6e-61
gi|157738621 kinesin family member 13A isoform a [Homo sapiens] 233 6e-61
gi|170784809 kinesin family member 17 isoform b [Homo sapiens] 233 6e-61
gi|170784807 kinesin family member 17 isoform a [Homo sapiens] 233 6e-61
gi|203096856 kinesin family member 7 [Homo sapiens] 232 1e-60
gi|38569484 kinesin family member 21A [Homo sapiens] 231 2e-60
gi|13699824 kinesin family member 11 [Homo sapiens] 231 2e-60
gi|40254834 kinesin family member 1C [Homo sapiens] 227 3e-59
gi|71061468 centromere protein E [Homo sapiens] 222 1e-57
gi|4758650 kinesin family member 5C [Homo sapiens] 221 2e-57
gi|9910266 kinesin family member 15 [Homo sapiens] 220 4e-57
gi|45446749 kinesin family member 5A [Homo sapiens] 218 2e-56
gi|4758648 kinesin family member 5B [Homo sapiens] 216 1e-55
>gi|148612831 kinesin family member 18A [Homo sapiens]
Length = 898
Score = 1795 bits (4649), Expect = 0.0
Identities = 898/898 (100%), Positives = 898/898 (100%)
Query: 1 MSVTEEDLCHHMKVVVRVRPENTKEKAAGFHKVVHVVDKHILVFDPKQEEVSFFHGKKTT 60
MSVTEEDLCHHMKVVVRVRPENTKEKAAGFHKVVHVVDKHILVFDPKQEEVSFFHGKKTT
Sbjct: 1 MSVTEEDLCHHMKVVVRVRPENTKEKAAGFHKVVHVVDKHILVFDPKQEEVSFFHGKKTT 60
Query: 61 NQNVIKKQNKDLKFVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKT 120
NQNVIKKQNKDLKFVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKT
Sbjct: 61 NQNVIKKQNKDLKFVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKT 120
Query: 121 HTMLGSADEPGVMYLTMLHLYKCMDEIKEEKICSTAVSYLEVYNEQIRDLLVNSGPLAVR 180
HTMLGSADEPGVMYLTMLHLYKCMDEIKEEKICSTAVSYLEVYNEQIRDLLVNSGPLAVR
Sbjct: 121 HTMLGSADEPGVMYLTMLHLYKCMDEIKEEKICSTAVSYLEVYNEQIRDLLVNSGPLAVR 180
Query: 181 EDTQKGVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQQD 240
EDTQKGVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQQD
Sbjct: 181 EDTQKGVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQQD 240
Query: 241 KTASINQNVRIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINALADSKR 300
KTASINQNVRIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINALADSKR
Sbjct: 241 KTASINQNVRIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINALADSKR 300
Query: 301 KNQHIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKDIKSSLK 360
KNQHIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKDIKSSLK
Sbjct: 301 KNQHIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKDIKSSLK 360
Query: 361 SNVLNVNNHITQYVKICNEQKAEILLLKEKLKAYEEQKAFTNENDQAKLMISNPQEKEIE 420
SNVLNVNNHITQYVKICNEQKAEILLLKEKLKAYEEQKAFTNENDQAKLMISNPQEKEIE
Sbjct: 361 SNVLNVNNHITQYVKICNEQKAEILLLKEKLKAYEEQKAFTNENDQAKLMISNPQEKEIE 420
Query: 421 RFQEILNCLFQNREEIRQEYLKLEMLLKENELKSFYQQQCHKQIEMMCSEDKVEKATGKR 480
RFQEILNCLFQNREEIRQEYLKLEMLLKENELKSFYQQQCHKQIEMMCSEDKVEKATGKR
Sbjct: 421 RFQEILNCLFQNREEIRQEYLKLEMLLKENELKSFYQQQCHKQIEMMCSEDKVEKATGKR 480
Query: 481 DHRLAMLKTRRSYLEKRREEELKQFDENTNWLHRVEKEMGLLSQNGHIPKELKKDLHCHH 540
DHRLAMLKTRRSYLEKRREEELKQFDENTNWLHRVEKEMGLLSQNGHIPKELKKDLHCHH
Sbjct: 481 DHRLAMLKTRRSYLEKRREEELKQFDENTNWLHRVEKEMGLLSQNGHIPKELKKDLHCHH 540
Query: 541 LHLQNKDLKAQIRHMMDLACLQEQQHRQTEAVLNALLPTLRKQYCTLKEAGLSNAAFESD 600
LHLQNKDLKAQIRHMMDLACLQEQQHRQTEAVLNALLPTLRKQYCTLKEAGLSNAAFESD
Sbjct: 541 LHLQNKDLKAQIRHMMDLACLQEQQHRQTEAVLNALLPTLRKQYCTLKEAGLSNAAFESD 600
Query: 601 FKEIEHLVERKKVVVWADQTAEQPKQNDLPGISVLMTFPQLGPVQPIPCCSSSGGTNLVK 660
FKEIEHLVERKKVVVWADQTAEQPKQNDLPGISVLMTFPQLGPVQPIPCCSSSGGTNLVK
Sbjct: 601 FKEIEHLVERKKVVVWADQTAEQPKQNDLPGISVLMTFPQLGPVQPIPCCSSSGGTNLVK 660
Query: 661 IPTEKRTRRKLMPSPLKGQHTLKSPPSQSVQLNDSLSKELQPIVYTPEDCRKAFQNPSTV 720
IPTEKRTRRKLMPSPLKGQHTLKSPPSQSVQLNDSLSKELQPIVYTPEDCRKAFQNPSTV
Sbjct: 661 IPTEKRTRRKLMPSPLKGQHTLKSPPSQSVQLNDSLSKELQPIVYTPEDCRKAFQNPSTV 720
Query: 721 TLMKPSSFTTSFQAISSNINSDNCLKMLCEVAIPHNRRKECGQEDLDSTFTICEDIKSSK 780
TLMKPSSFTTSFQAISSNINSDNCLKMLCEVAIPHNRRKECGQEDLDSTFTICEDIKSSK
Sbjct: 721 TLMKPSSFTTSFQAISSNINSDNCLKMLCEVAIPHNRRKECGQEDLDSTFTICEDIKSSK 780
Query: 781 CKLPEQESLPNDNKDILQRLDPSSFSTKHSMPVPSMVPSYMAMTTAAKRKRKLTSSTSNS 840
CKLPEQESLPNDNKDILQRLDPSSFSTKHSMPVPSMVPSYMAMTTAAKRKRKLTSSTSNS
Sbjct: 781 CKLPEQESLPNDNKDILQRLDPSSFSTKHSMPVPSMVPSYMAMTTAAKRKRKLTSSTSNS 840
Query: 841 SLTADVNSGFAKRVRQDNSSEKHLQENKPTMEHKRNICKINPSMVRKFGRNISKGNLR 898
SLTADVNSGFAKRVRQDNSSEKHLQENKPTMEHKRNICKINPSMVRKFGRNISKGNLR
Sbjct: 841 SLTADVNSGFAKRVRQDNSSEKHLQENKPTMEHKRNICKINPSMVRKFGRNISKGNLR 898
>gi|122937289 kinesin family member 18B [Homo sapiens]
Length = 855
Score = 465 bits (1197), Expect = e-131
Identities = 231/384 (60%), Positives = 297/384 (77%)
Query: 12 MKVVVRVRPENTKEKAAGFHKVVHVVDKHILVFDPKQEEVSFFHGKKTTNQNVIKKQNKD 71
++VVVRVRP +E + VV VVD+ +LVF+P++ + F K + KK+ KD
Sbjct: 8 LQVVVRVRPPTPRELDSQRRPVVQVVDERVLVFNPEEPDGGFPGLKWGGTHDGPKKKGKD 67
Query: 72 LKFVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTMLGSADEPG 131
L FVFD VF E +TQ +VF+HTT +L SFL GYNC+V AYGATGAGKTHTMLG +PG
Sbjct: 68 LTFVFDRVFGEAATQQDVFQHTTHSVLDSFLQGYNCSVFAYGATGAGKTHTMLGREGDPG 127
Query: 132 VMYLTMLHLYKCMDEIKEEKICSTAVSYLEVYNEQIRDLLVNSGPLAVREDTQKGVVVHG 191
+MYLT + LY+ ++ ++EK +SY EVYNEQI DLL GPLA+RED KGVVV G
Sbjct: 128 IMYLTTVELYRRLEARQQEKHFEVLISYQEVYNEQIHDLLEPKGPLAIREDPDKGVVVQG 187
Query: 192 LTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQQDKTASINQNVRI 251
L+ HQP S+E++L +L GN+NRTQHPTD NATSSRSHA+FQI+++QQD+ + Q V++
Sbjct: 188 LSFHQPASAEQLLEILTRGNRNRTQHPTDANATSSRSHAIFQIFVKQQDRVPGLTQAVQV 247
Query: 252 AKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINALADSKRKNQHIPYRNSK 311
AKMSLIDLAGSERAS++ AKG R EG NINRSLLAL NV+NALAD+K + H+PYR+SK
Sbjct: 248 AKMSLIDLAGSERASSTHAKGERLREGANINRSLLALINVLNALADAKGRKTHVPYRDSK 307
Query: 312 LTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKDIKSSLKSNVLNVNNHIT 371
LTRLLKDSLGGNC+T+MIAA+SPSS+ Y+DTYNTLKYA+RAK+I+ SLKSNV +++ HI+
Sbjct: 308 LTRLLKDSLGGNCRTVMIAAISPSSLTYEDTYNTLKYADRAKEIRLSLKSNVTSLDCHIS 367
Query: 372 QYVKICNEQKAEILLLKEKLKAYE 395
QY IC + +AE+ L++KL+ YE
Sbjct: 368 QYATICQQLQAEVAALRKKLQVYE 391
>gi|156616271 kinesin family member 19 [Homo sapiens]
Length = 998
Score = 327 bits (837), Expect = 4e-89
Identities = 188/444 (42%), Positives = 279/444 (62%), Gaps = 22/444 (4%)
Query: 12 MKVVVRVRPENTKEKAAGFHKVVHVVDKHILVF-DPKQEEVSFFHGKKTTNQNVIKKQNK 70
+ V +RVRP + E G + H VD+ ++V DP ++ ++ +
Sbjct: 12 LMVALRVRPISVAELEEGATLIAHKVDEQMVVLMDPMEDPDDILRAHRS----------R 61
Query: 71 DLKFVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTMLGSADEP 130
+ ++FD FD T+TQ V++ TTK ++ ++GYN TV AYG TG GKT+TMLG+ EP
Sbjct: 62 EKSYLFDVAFDFTATQEMVYQATTKSLIEGVISGYNATVFAYGPTGCGKTYTMLGTDQEP 121
Query: 131 GVMYLTMLHLYKCMDEIKEEKICSTAVSYLEVYNEQIRDLLVNS-GPLAVREDTQKGVVV 189
G+ T+ L++ ++E + ++SYLE+YNE IRDLL S G L +RED++ + V
Sbjct: 122 GIYVQTLNDLFRAIEETSNDMEYEVSMSYLEIYNEMIRDLLNPSLGYLELREDSKGVIQV 181
Query: 190 HGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQQDKTASINQNV 249
G+T +++EI+ LL GN+ RTQ PT N TSSRSHAV Q+ +RQ+ + +I Q V
Sbjct: 182 AGITEVSTINAKEIMQLLMKGNRQRTQEPTAANQTSSRSHAVLQVTVRQRSRVKNILQEV 241
Query: 250 RIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINALADSKRKNQHIPYRN 309
R ++ +IDLAGSERAS + +G R EG +INRSLLALGN INAL+D K N++I YR+
Sbjct: 242 RQGRLFMIDLAGSERASQTQNRGQRMKEGAHINRSLLALGNCINALSD-KGSNKYINYRD 300
Query: 310 SKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKDIKSSLKSNVLNVNNH 369
SKLTRLLKDSLGGN +T+MIA +SP+S ++++ NTL YA RAK+IK+ +K N+LNV+ H
Sbjct: 301 SKLTRLLKDSLGGNSRTVMIAHISPASSAFEESRNTLTYAGRAKNIKTRVKQNLLNVSYH 360
Query: 370 ITQYVKICNEQKAEILLLKEKL-------KAYEEQKAFTNENDQAKLMISNPQEKE--IE 420
I QY I + + EI LK K+ +A Q + QA++ + + Q ++ +
Sbjct: 361 IAQYTSIIADLRGEIQRLKRKIDEQTGRGQARGRQDRGDIRHIQAEVQLHSGQGEKAGMG 420
Query: 421 RFQEILNCLFQNREEIRQEYLKLE 444
+ +E L FQ + ++R+ L+LE
Sbjct: 421 QLREQLASAFQEQMDVRRRLLELE 444
>gi|4758646 kinesin family member 3B [Homo sapiens]
Length = 747
Score = 264 bits (674), Expect = 3e-70
Identities = 205/595 (34%), Positives = 318/595 (53%), Gaps = 67/595 (11%)
Query: 12 MKVVVRVRPENTKEKAAGFHKVVHVVDKHILVFDPKQEEVSFFHGKKTTNQNVIKKQNKD 71
++VVVR RP N KEKAA + KVV V D K +VS + K T ++
Sbjct: 10 VRVVVRCRPMNGKEKAASYDKVVDV--------DVKLGQVSVKNPKGTAHE-------MP 54
Query: 72 LKFVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTMLGSADEP- 130
F FDAV+D + Q E+++ T +P++ S L G+N T+ AYG TG GKT+TM G +P
Sbjct: 55 KTFTFDAVYDWNAKQFELYDETFRPLVDSVLQGFNGTIFAYGQTGTGKTYTMEGIRGDPE 114
Query: 131 --GVMYLTMLHLYKCMDEIKEEKICSTAVSYLEVYNEQIRDLLVNSGP--LAVREDTQKG 186
GV+ + H++ + + ++ A SYLE+Y E+IRDLL L ++E G
Sbjct: 115 KRGVIPNSFDHIFTHISRSQNQQYLVRA-SYLEIYQEEIRDLLSKDQTKRLELKERPDTG 173
Query: 187 VVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQQDKTASIN 246
V V L+ KS +EI H+++ GN+NR+ T+MN SSRSHA+F I + +
Sbjct: 174 VYVKDLSSFVTKSVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIECSEVGLDGE 233
Query: 247 QNVRIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINALADSKRKNQHIP 306
++R+ K++L+DLAGSER + +GA+G R E T IN SL ALGNVI+AL D K+ HIP
Sbjct: 234 NHIRVGKLNLVDLAGSERQAKTGAQGERLKEATKINLSLSALGNVISALVDG--KSTHIP 291
Query: 307 YRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKDIKSSLKSNVLNV 366
YR+SKLTRLL+DSLGGN +T+M+A V P+S ++T TL+YANRAK+IK+ + N
Sbjct: 292 YRDSKLTRLLQDSLGGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNKPRVNEDPK 351
Query: 367 NNHITQYVKICNEQKAEI-------LLLKEKLK-----------AYEEQKAFTNENDQAK 408
+ + ++ + KA++ +EK + EE + E D
Sbjct: 352 DALLREFQEEIARLKAQLEKRSIGRRKRREKRREGGGSGGGGEEEEEEGEEGEEEGDDKD 411
Query: 409 LMISNPQEK-EIERFQEILNCLFQNREEIRQEYLKLEMLLKENELKSFYQQQCHKQIEMM 467
QEK EIE+ + ++ + +E ++ LLKE E K ++ EM+
Sbjct: 412 DYWREQQEKLEIEK-----RAIVEDHSLVAEEKMR---LLKEKEKKMEDLRREKDAAEML 463
Query: 468 CSEDKVEKAT----GKR--DH---RLAMLKTRRSYL--EKRREEELKQFDENTNWLHRVE 516
++ K ++ GK DH + +L+ +R + +KRRE E++Q E+ R E
Sbjct: 464 GAKIKAMESKLLVGGKNIVDHTNEQQKILEQKRQEIAEQKRREREIQQQMES-----RDE 518
Query: 517 KEMGLLSQNGHIPKELK-KDLHCHHLHLQNKDLKAQIRHMMDLACLQEQQHRQTE 570
+ + L + +E+ K L + + +KA+I + + + Q+ QT+
Sbjct: 519 ETLELKETYSSLQQEVDIKTKKLKKLFSKLQAVKAEIHDLQEEHIKERQELEQTQ 573
>gi|46852174 kinesin family member 3A [Homo sapiens]
Length = 699
Score = 261 bits (667), Expect = 2e-69
Identities = 200/612 (32%), Positives = 315/612 (51%), Gaps = 58/612 (9%)
Query: 9 CHHMKVVVRVRPENTKEKAAGFHKVVHVVDKHILVFDPKQEEVSFFHGKKTTNQNVIKKQ 68
C ++KVVVR RP N +EK+ + + V V D + ++ KT + N K
Sbjct: 12 CDNVKVVVRCRPLNEREKSMCYKQAVSV--------DEMRGTITVH---KTDSSNEPPKT 60
Query: 69 NKDLKFVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTMLGSAD 128
F FD VF S Q +V+ T +PI+ S L GYN T+ AYG TG GKT TM G
Sbjct: 61 -----FTFDTVFGPESKQLDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRA 115
Query: 129 EP---GVMYLTMLHLYKCMDEIKEEKICSTAVSYLEVYNEQIRDLLVNSGP--LAVREDT 183
P G++ + H++ + + + + VSYLE+YNE++RDLL L V+E
Sbjct: 116 IPELRGIIPNSFAHIFGHIAKAEGDTRFLVRVSYLEIYNEEVRDLLGKDQTQRLEVKERP 175
Query: 184 QKGVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQQDKTA 243
GV + L+ + +++++ ++ G+KNR+ T+MN SSRSHA+F I + +K
Sbjct: 176 DVGVYIKDLSAYVVNNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGI 235
Query: 244 SINQNVRIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINALADSKRKNQ 303
N +VR+ K+ L+DLAGSER + +GA G R E T IN SL LGNVI+AL D K+
Sbjct: 236 DGNMHVRMGKLHLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVDG--KST 293
Query: 304 HIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKDIKSSLKSNV 363
H+PYRNSKLTRLL+DSLGGN +T+M A + P+ YD+T +TL+YANRAK+IK+ + N
Sbjct: 294 HVPYRNSKLTRLLQDSLGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARINE 353
Query: 364 LNVNNHITQYVKICNEQKAEILLLKEKLKAYEE----QKAFTNENDQAKLMISNPQEKEI 419
+ + Q+ K EI LK+KL+ EE + + E+D + + EK
Sbjct: 354 DPKDALLRQFQK-------EIEELKKKLEEGEEISGSDISGSEEDDDEEGEVGEDGEKRK 406
Query: 420 ERFQEILNCLFQNREEIRQEYLKLEMLLKENELKSFYQQQCHKQIEMMCSEDKVEKATGK 479
+R + ++++ + + +EM K +E + + + + E +K K
Sbjct: 407 KR---------RGKKKVSPDKM-IEMQAKIDEERKALETKLDMEEE---ERNKARAELEK 453
Query: 480 RDHRLAML-KTRRSYLEKRREEELKQFDENTNWLHRVEKEMGLLSQNGHIPKELKKDLHC 538
R+ L + +S LEK E K + L + E++ LL ++ +E +K
Sbjct: 454 REKDLLKAQQEHQSLLEKLSALEKKVIVGGVDLLAKAEEQEKLLEESNMELEERRKRAEQ 513
Query: 539 HHLHLQNKDLKAQIRHMMDLACLQEQQHRQTEAVLNALLPTLRKQYCTLKEAGLSNAAFE 598
L+ K+ + +D+ E+++ + L+K + L A A +
Sbjct: 514 LRRELEEKE-----QERLDI----EEKYTSLQEEAQGKTKKLKKVWTMLMAAKSEMADLQ 564
Query: 599 SDF-KEIEHLVE 609
+ +EIE L+E
Sbjct: 565 QEHQREIEGLLE 576
>gi|41393559 kinesin family member 1B isoform alpha [Homo sapiens]
Length = 1153
Score = 241 bits (616), Expect = 2e-63
Identities = 173/479 (36%), Positives = 251/479 (52%), Gaps = 63/479 (13%)
Query: 12 MKVVVRVRPENTKEKAAGFHKVVHVVDKHILVFDPKQEEVSFFHGKKTTNQNVIKKQNKD 71
+KV VRVRP N++E + ++ + + +PK K+ K
Sbjct: 6 VKVAVRVRPFNSRETSKESKCIIQMQGNSTSIINPKNP----------------KEAPKS 49
Query: 72 LKFVFDAVFDETS-------TQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTML 124
F + + + TS +Q+ V+ K +L GYN + AYG TGAGK++TM+
Sbjct: 50 FSFDY-SYWSHTSPEDPCFASQNRVYNDIGKEMLLHAFEGYNVCIFAYGQTGAGKSYTMM 108
Query: 125 GSADEP--GVMYLTMLHLY-KCMDEIKEEKICSTAVSYLEVYNEQIRDLL--VNSGPLAV 179
G +E G++ L+ K D EE S VSY+E+Y E++RDLL N G L V
Sbjct: 109 GKQEESQAGIIPQLCEELFEKINDNCNEEMSYSVEVSYMEIYCERVRDLLNPKNKGNLRV 168
Query: 180 REDTQKGVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQQ 239
RE G V L+ S +I L+D GNK RT T+MN TSSRSHAVF I Q+
Sbjct: 169 REHPLLGPYVEDLSKLAVTSYTDIADLMDAGNKARTVAATNMNETSSRSHAVFTIVFTQK 228
Query: 240 DKTASINQNV-RIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINALAD- 297
N + +++K+SL+DLAGSERA ++GAKGTR EG NIN+SL LG VI+ALA+
Sbjct: 229 KHDNETNLSTEKVSKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEV 288
Query: 298 --SKRKNQHIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKDI 355
K+K IPYR+S LT LL+++LGGN +T M+AA+SP+ + YD+T +TL+YA+RAK I
Sbjct: 289 SKKKKKTDFIPYRDSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQI 348
Query: 356 KSSLKSNVLNVNNHITQYVKICNEQKAEILLLKEKLKA---------------------- 393
K + V+N + + K+ E K E+ LK+ L+A
Sbjct: 349 KCNA---VINEDPN----AKLVRELKEEVTRLKDLLRAQGLGDIIDTSMGSLTSSPSSCS 401
Query: 394 YEEQKAFTNEND-QAKLMISNPQEKEIERFQEILNCLFQNREEIRQEYLKLEMLLKENE 451
Q T+ Q ++M + E+ IER +E + + E ++ K E + E E
Sbjct: 402 LSSQVGLTSVTSIQERIMSTPGGEEAIERLKESEKIIAELNETWEEKLRKTEAIRMERE 460
>gi|41393563 kinesin family member 1B isoform b [Homo sapiens]
Length = 1770
Score = 241 bits (616), Expect = 2e-63
Identities = 173/479 (36%), Positives = 251/479 (52%), Gaps = 63/479 (13%)
Query: 12 MKVVVRVRPENTKEKAAGFHKVVHVVDKHILVFDPKQEEVSFFHGKKTTNQNVIKKQNKD 71
+KV VRVRP N++E + ++ + + +PK K+ K
Sbjct: 6 VKVAVRVRPFNSRETSKESKCIIQMQGNSTSIINPKNP----------------KEAPKS 49
Query: 72 LKFVFDAVFDETS-------TQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTML 124
F + + + TS +Q+ V+ K +L GYN + AYG TGAGK++TM+
Sbjct: 50 FSFDY-SYWSHTSPEDPCFASQNRVYNDIGKEMLLHAFEGYNVCIFAYGQTGAGKSYTMM 108
Query: 125 GSADEP--GVMYLTMLHLY-KCMDEIKEEKICSTAVSYLEVYNEQIRDLL--VNSGPLAV 179
G +E G++ L+ K D EE S VSY+E+Y E++RDLL N G L V
Sbjct: 109 GKQEESQAGIIPQLCEELFEKINDNCNEEMSYSVEVSYMEIYCERVRDLLNPKNKGNLRV 168
Query: 180 REDTQKGVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQQ 239
RE G V L+ S +I L+D GNK RT T+MN TSSRSHAVF I Q+
Sbjct: 169 REHPLLGPYVEDLSKLAVTSYTDIADLMDAGNKARTVAATNMNETSSRSHAVFTIVFTQK 228
Query: 240 DKTASINQNV-RIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINALAD- 297
N + +++K+SL+DLAGSERA ++GAKGTR EG NIN+SL LG VI+ALA+
Sbjct: 229 KHDNETNLSTEKVSKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEV 288
Query: 298 --SKRKNQHIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKDI 355
K+K IPYR+S LT LL+++LGGN +T M+AA+SP+ + YD+T +TL+YA+RAK I
Sbjct: 289 SKKKKKTDFIPYRDSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQI 348
Query: 356 KSSLKSNVLNVNNHITQYVKICNEQKAEILLLKEKLKA---------------------- 393
K + V+N + + K+ E K E+ LK+ L+A
Sbjct: 349 KCNA---VINEDPN----AKLVRELKEEVTRLKDLLRAQGLGDIIDTSMGSLTSSPSSCS 401
Query: 394 YEEQKAFTNEND-QAKLMISNPQEKEIERFQEILNCLFQNREEIRQEYLKLEMLLKENE 451
Q T+ Q ++M + E+ IER +E + + E ++ K E + E E
Sbjct: 402 LSSQVGLTSVTSIQERIMSTPGGEEAIERLKESEKIIAELNETWEEKLRKTEAIRMERE 460
>gi|116686122 kinesin family member 4 [Homo sapiens]
Length = 1232
Score = 241 bits (616), Expect = 2e-63
Identities = 169/437 (38%), Positives = 248/437 (56%), Gaps = 56/437 (12%)
Query: 71 DLKFVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTMLGS---- 126
D F +D VFD ++ Q EVF P+++ GYN TVLAYG TG+GKT++M G+
Sbjct: 46 DKSFTYDFVFDPSTEQEEVFNTAVAPLIKGVFKGYNATVLAYGQTGSGKTYSMGGAYTAE 105
Query: 127 -ADEP--GVMYLTMLHLYKCMDEIKEEKICSTAVSYLEVYNEQIRDLLVNSGPLA---VR 180
+EP GV+ + L+K +D+ K + + VSYLE+YNE+I DLL S A +R
Sbjct: 106 QENEPTVGVIPRVIQLLFKEIDK-KSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIR 164
Query: 181 EDTQKGVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQQD 240
ED ++G+ + GLT + + + L+ GN +RT T MN+ SSRSHA+F I L Q+
Sbjct: 165 EDPKEGIKIVGLTEKTVLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISLEQRK 224
Query: 241 KTASINQNVRIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINALADSKR 300
K+ N + R +K+ L+DLAGSER + A+G R EG NINR LL LGNVI+AL D K
Sbjct: 225 KSDK-NSSFR-SKLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDK- 281
Query: 301 KNQHIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKDIKSSLK 360
K +PYR+SKLTRLL+DSLGGN T+MIA VSP+ ++T NTL+YA+RA+ IK+
Sbjct: 282 KGGFVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLNTLRYADRARKIKN--- 338
Query: 361 SNVLNVN------NHITQYVKICNEQKAEILLLK---------------EKLKA-YEEQK 398
++N++ NH+ Q V Q+ ++LLL+ E L++ E+ +
Sbjct: 339 KPIVNIDPQTAELNHLKQQV-----QQLQVLLLQAHGGTLPGSITVEPSENLQSLMEKNQ 393
Query: 399 AFTNENDQAKLMISNPQEKEIERFQEILNCLFQNR------EEIRQ------EYLKLEML 446
+ EN++ +S + + + I+ N EE+RQ + KL
Sbjct: 394 SLVEENEKLSRGLSEAAGQTAQMLERIILTEQANEKMNAKLEELRQHAACKLDLQKLVET 453
Query: 447 LKENELKSFYQQQCHKQ 463
L++ ELK + C+ Q
Sbjct: 454 LEDQELKENVEIICNLQ 470
>gi|46852172 kinesin family member 13B [Homo sapiens]
Length = 1826
Score = 239 bits (611), Expect = 6e-63
Identities = 169/443 (38%), Positives = 249/443 (56%), Gaps = 33/443 (7%)
Query: 12 MKVVVRVRPENTKEKAAGFH-KVVHVVDKHILVFDPKQEEVSFFHGKKTTNQNVIKKQNK 70
+KV VR+RP N +E H K V VD + ++ +P +S + Q + +
Sbjct: 6 VKVAVRIRPMNRRE--TDLHTKCVVDVDANKVILNPVNTNLSKGDAR---GQPKVFAYDH 60
Query: 71 DLKFVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTMLGSADEP 130
+ ++V ++ + Q VF+ + IL++ +GYN + AYG TG+GK++TM+G+AD+P
Sbjct: 61 CFWSMDESVKEKYAGQDIVFKCLGENILQNAFDGYNACIFAYGQTGSGKSYTMMGTADQP 120
Query: 131 GVMYLTMLHLY-KCMDEIKEEKICSTAVSYLEVYNEQIRDLLVNSGP---LAVREDTQKG 186
G++ L+ + E EE+ VSY+E+YNE++RDLL G L VRE + G
Sbjct: 121 GLIPRLCSGLFERTQKEENEEQSFKVEVSYMEIYNEKVRDLLDPKGSRQTLKVREHSVLG 180
Query: 187 VVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQQ-DKTASI 245
V GL+ S ++I L+ GNK+RT T+MN SSRSHAVF+I L S
Sbjct: 181 PYVDGLSKLAVTSYKDIESLMSEGNKSRTVAATNMNEESSRSHAVFKITLTHTLYDVKSG 240
Query: 246 NQNVRIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINALADS---KRKN 302
++ K+SL+DLAGSERA+ +GA G R EG+NIN+SL LG VI+ALAD K KN
Sbjct: 241 TSGEKVGKLSLVDLAGSERATKTGAAGDRLKEGSNINKSLTTLGLVISALADQSAGKNKN 300
Query: 303 QHIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKDIKSSLKSN 362
+ +PYR+S LT LLKDSLGGN +T M+A VSP++ YD+T +TL+YA+RAK
Sbjct: 301 KFVPYRDSVLTWLLKDSLGGNSKTAMVATVSPAADNYDETLSTLRYADRAK--------- 351
Query: 363 VLNVNNHITQYVKICNEQKAEILL-LKEKLKAYEEQ--KAFTNENDQAKLMISNPQEKEI 419
HI + + + A I+ L+E+++ EQ KA ++ + K + EK I
Sbjct: 352 ------HIVNHAVVNEDPNARIIRDLREEVEKLREQLTKAEAMKSPELKDRLEE-SEKLI 404
Query: 420 ERFQEILNCLFQNREEIRQEYLK 442
+ + EEI QE K
Sbjct: 405 QEMTVTWEEKLRKTEEIAQERQK 427
>gi|150010604 kinesin family member 4B [Homo sapiens]
Length = 1234
Score = 239 bits (610), Expect = 8e-63
Identities = 163/432 (37%), Positives = 246/432 (56%), Gaps = 46/432 (10%)
Query: 71 DLKFVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTMLGS---- 126
D F +D VFD + Q EVF P+++ GYN TVLAYG TG+GKT++M G+
Sbjct: 46 DKSFTYDFVFDPCTEQEEVFNKAVAPLIKGIFKGYNATVLAYGQTGSGKTYSMGGAYTAE 105
Query: 127 -ADEP--GVMYLTMLHLYKCMDEIKEEKICSTAVSYLEVYNEQIRDLLVNSGPLA---VR 180
+EP G++ + L+K +D+ K + + VSYLE+YNE+I DLL S A +R
Sbjct: 106 QENEPTVGIIPRVIQLLFKEIDK-KSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIR 164
Query: 181 EDTQKGVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQQD 240
ED ++G+ + GLT + + + L+ GN +RT T MN+ SSRSHA+F I + Q+
Sbjct: 165 EDPKEGIKIVGLTEKTVLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISIEQRK 224
Query: 241 KTASINQNVRIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINALADSKR 300
K+ N + R +K+ L+DLAGSER + A+G R EG NINR LL LGNVI+AL D K
Sbjct: 225 KSDK-NCSFR-SKLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDK- 281
Query: 301 KNQHIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKDIKSSLK 360
K +PYR+SKLTRLL+DSLGGN T+MIA VSP+ ++T +TL+YA+RA+ IK+
Sbjct: 282 KGSFVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLSTLRYADRARKIKN--- 338
Query: 361 SNVLNVNNHITQYVKICNE-QKAEILLLK---------------EKLKA-YEEQKAFTNE 403
++N++ H + + + Q+ ++LLL+ E L++ E+ ++ E
Sbjct: 339 KPIVNIDPHTAELNHLKQQVQQLQVLLLQAHGGTLPGSINAEPSENLQSLMEKNQSLVEE 398
Query: 404 NDQAKLMISNPQEKEIERFQEIL------NCLFQNREEIRQ------EYLKLEMLLKENE 451
N++ +S + + + I+ L EE+RQ + KL L++ E
Sbjct: 399 NEKLSRCLSKAAGQTAQMLERIILTEQVNEKLNAKLEELRQHVACKLDLQKLVETLEDQE 458
Query: 452 LKSFYQQQCHKQ 463
LK + C+ Q
Sbjct: 459 LKENVEIICNLQ 470
>gi|41352705 kinesin family member 3C [Homo sapiens]
Length = 793
Score = 239 bits (609), Expect = 1e-62
Identities = 198/640 (30%), Positives = 324/640 (50%), Gaps = 108/640 (16%)
Query: 12 MKVVVRVRPENTKEKAAGFHKVVHVVDKHILVFDPKQEEVSFFHGKKTTNQNVIKKQNKD 71
+KVV R RP + KE+AAG + IL D K +V+ + + +
Sbjct: 11 LKVVARCRPLSRKEEAAGHEQ--------ILTMDVKLGQVTLRNPRAAPGE-------LP 55
Query: 72 LKFVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTMLGSADEP- 130
F FDAV+D +S Q+++++ T +P++ S L G+N TV AYG TG GKT+TM G+ EP
Sbjct: 56 KTFTFDAVYDASSKQADLYDETVRPLIDSVLQGFNGTVFAYGQTGTGKTYTMQGTWVEPE 115
Query: 131 --GVMYLTMLHLYKCMDEIKEEKICSTAVSYLEVYNEQIRDLLVNSGP--LAVREDTQKG 186
GV+ H++ + + ++ A SYLE+Y E+IRDLL L ++E+ + G
Sbjct: 116 LRGVIPNAFEHIFTHISRSQNQQYLVRA-SYLEIYQEEIRDLLSKEPGKRLELKENPETG 174
Query: 187 VVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQQDKTASIN 246
V + L+ K+ +EI H+++ GN+ R T MN SSRSHA+F I + ++ +
Sbjct: 175 VYIKDLSSFVTKNVKEIEHVMNLGNQTRAVGSTHMNEVSSRSHAIFIITVECSERGSDGQ 234
Query: 247 QNVRIAKMSLIDLAGSER------------------------ASTSGAKGTRFVEGTNIN 282
++R+ K++L+DLAGSER S GA G R E + IN
Sbjct: 235 DHIRVGKLNLVDLAGSERQNKAGPNTAGGAATPSSGGGGGGGGSGGGAGGERPKEASKIN 294
Query: 283 RSLLALGNVINALADSKRKNQHIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDT 342
SL ALGNVI ALA ++ + HIPYR+SKLTRLL+DSLGGN +TIM+A + P+S YD++
Sbjct: 295 LSLSALGNVIAALAGNR--STHIPYRDSKLTRLLQDSLGGNAKTIMVATLGPASHSYDES 352
Query: 343 YNTLKYANRAKDIKSSLKSNVLNVNNHITQYVKICNEQKAEI-----LLLKEKLKAYEEQ 397
+TL++ANRAK+IK+ + N + + ++ + KA++ L + + K+ +
Sbjct: 353 LSTLRFANRAKNIKNKPRVNEDPKDTLLREFQEEIARLKAQLEKRGMLGKRPRRKSSRRK 412
Query: 398 KAFT---------------------NENDQ----------AKLMISNPQEKEIERFQEIL 426
KA + N N+ + + N +++ ER +E
Sbjct: 413 KAVSAPPGYPEGPVIEAWVAEEEDDNNNNHRPPQPILESALEKNMENYLQEQKERLEEEK 472
Query: 427 NCLFQNREEIRQEYLKLEMLLKENELKSFYQQQCHKQIEMMCSEDKVEKA---TGKR--- 480
+ +R + +E KL + KE L+ ++Q + E++ ++ K ++ G R
Sbjct: 473 AAIQDDRSLVSEEKQKL-LEEKEKMLEDLRREQ--QATELLAAKYKAMESKLLIGGRNIM 529
Query: 481 DH-----RLAMLKTRRSYLEKRREEELKQFDENTNWLHRVEKEMGLLSQNGHIPKELK-K 534
DH ++ LK + +KRRE E++Q + R E+ M L + +E++ K
Sbjct: 530 DHTNEQQKMLELKRQEIAEQKRREREMQQ-----EMMLRDEETMELRGTYTSLQQEVEVK 584
Query: 535 DLHCHHLHLQNKDLKAQIRHMMD-----LACLQEQQHRQT 569
L+ + + +KA+I+ D L+E Q+ QT
Sbjct: 585 TKKLKKLYAKLQAVKAEIQDQHDEYIRVRQDLEEAQNEQT 624
>gi|30794488 kinesin family member 27 [Homo sapiens]
Length = 1401
Score = 237 bits (605), Expect = 3e-62
Identities = 151/400 (37%), Positives = 219/400 (54%), Gaps = 47/400 (11%)
Query: 12 MKVVVRVRPENTKEKAAGFHKVVHVVDKHILVFDPKQEEVSFFHGKKTTNQNVIKKQNKD 71
+KV VR+RP KE V V+ P ++V +D
Sbjct: 6 VKVAVRIRPLLCKEALHNHQVCVRVI--------PNSQQVII---------------GRD 42
Query: 72 LKFVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTMLGS----- 126
F FD VF + STQ EV+ KP++ S + GYN TV AYG TG+GKT+T+ G
Sbjct: 43 RVFTFDFVFGKNSTQDEVYNTCIKPLVLSLIEGYNATVFAYGQTGSGKTYTIGGGHIASV 102
Query: 127 -ADEPGVMYLTMLHLYKCMDEIKEEKICSTAVSYLEVYNEQIRDLL---VNSGPLAVRED 182
+ G++ + +++ + E + VSY+EVY E +RDLL + L +RED
Sbjct: 103 VEGQKGIIPRAIQEIFQSISEHPSIDF-NVKVSYIEVYKEDLRDLLELETSMKDLHIRED 161
Query: 183 TQKGVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQQDKT 242
+ V+ G +S+ E++ LL+ GN R T MN SSRSHA+F I + Q K
Sbjct: 162 EKGNTVIVGAKECHVESAGEVMSLLEMGNAARHTGTTQMNEHSSRSHAIFTISICQVHKN 221
Query: 243 ASINQNVR-------IAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINAL 295
++ ++K +DLAGSER + +G G RF E IN LLALGNVI+AL
Sbjct: 222 MEAAEDGSWYSPRHIVSKFHFVDLAGSERVTKTGNTGERFKESIQINSGLLALGNVISAL 281
Query: 296 ADSKRKNQHIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKDI 355
D +RK+ HIPYR++K+TRLLKDSLGG+ +T+MI VSPSS +D++ N+LKYANRA++I
Sbjct: 282 GDPRRKSSHIPYRDAKITRLLKDSLGGSAKTVMITCVSPSSSNFDESLNSLKYANRARNI 341
Query: 356 KSSLKSNVLNVNNHITQYVKICNEQKAEILLLKEKLKAYE 395
++ N ++ I +E + EI LL+E L++ +
Sbjct: 342 RNKPTVNFSPESDRI-------DEMEFEIKLLREALQSQQ 374
>gi|19924175 axonal transport of synaptic vesicles [Homo sapiens]
Length = 1690
Score = 234 bits (598), Expect = 2e-61
Identities = 155/404 (38%), Positives = 228/404 (56%), Gaps = 46/404 (11%)
Query: 12 MKVVVRVRPENTKEKAAGFHKVVHVVDKHILVFDPKQEEVSFFHGKKTTNQNVIKKQNKD 71
+KV VRVRP N++E + ++ + + +PKQ K+ K
Sbjct: 6 VKVAVRVRPFNSREMSRDSKCIIQMSGSTTTIVNPKQP----------------KETPKS 49
Query: 72 LKFVFDAVFDETS-------TQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTML 124
F + + + TS +Q +V+ + +L+ GYN + AYG TGAGK++TM+
Sbjct: 50 FSFDY-SYWSHTSPEDINYASQKQVYRDIGEEMLQHAFEGYNVCIFAYGQTGAGKSYTMM 108
Query: 125 GSA--DEPGVMYLTMLHLYKCMDEIKEEKIC-STAVSYLEVYNEQIRDLL--VNSGPLAV 179
G D+ G++ L+ +++ + + S VSY+E+Y E++RDLL N G L V
Sbjct: 109 GKQEKDQQGIIPQLCEDLFSRINDTTNDNMSYSVEVSYMEIYCERVRDLLNPKNKGNLRV 168
Query: 180 REDTQKGVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQQ 239
RE G V L+ S +I L+D+GNK RT T+MN TSSRSHAVF I Q+
Sbjct: 169 REHPLLGPYVEDLSKLAVTSYNDIQDLMDSGNKARTVAATNMNETSSRSHAVFNIIFTQK 228
Query: 240 DKTASINQNV-RIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINALAD- 297
A N +++K+SL+DLAGSERA ++GAKGTR EG NIN+SL LG VI+ALA+
Sbjct: 229 RHDAETNITTEKVSKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEM 288
Query: 298 --------SKRKNQHIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYA 349
K+K IPYR+S LT LL+++LGGN +T M+AA+SP+ + YD+T +TL+YA
Sbjct: 289 DSGPNKNKKKKKTDFIPYRDSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYA 348
Query: 350 NRAKDIKSSLKSNVLNVNNHITQYVKICNEQKAEILLLKEKLKA 393
+RAK I+ + N + NN K+ E K E+ L++ L A
Sbjct: 349 DRAKQIRCNAVINE-DPNN------KLIRELKDEVTRLRDLLYA 385
>gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]
Length = 1317
Score = 234 bits (596), Expect = 4e-61
Identities = 170/464 (36%), Positives = 245/464 (52%), Gaps = 47/464 (10%)
Query: 12 MKVVVRVRPENTKEKAAGFHKVVHVVDKHILVFDPKQEEVSFFHGKKTTNQNVIKKQNKD 71
+KV VRVRP N +EK ++ + + + K E G + + K D
Sbjct: 4 VKVAVRVRPMNRREKDLEAKFIIQMEKSKTTITNLKIPE----GGTGDSGRERTKTFTYD 59
Query: 72 LKFVF-DAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTMLGSADEP 130
F D + +Q VF+ +++S GYN V AYG TG+GK++TM+G++ +
Sbjct: 60 FSFYSADTKSPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMGNSGDS 119
Query: 131 GVMYLTMLHLYKCMDEIK--EEKICSTAVSYLEVYNEQIRDLLVNSGP----LAVREDTQ 184
G++ L+ ++E +E T VSYLE+YNE++RDLL L VRE +
Sbjct: 120 GLIPRICEGLFSRINETTRWDEASFRTEVSYLEIYNERVRDLLRRKSSKTFNLRVREHPK 179
Query: 185 KGVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQQDKTAS 244
+G V L+ H ++ ++ L+D GN NRT T MN SSRSHA+F I Q K S
Sbjct: 180 EGPYVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRSHAIFTIKFTQA-KFDS 238
Query: 245 INQNVRIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINALAD------- 297
++K+ L+DLAGSERA +GA G R EG NIN+SL+ LGNVI+ALAD
Sbjct: 239 EMPCETVSKIHLVDLAGSERADATGATGVRLKEGGNINKSLVTLGNVISALADLSQDAAN 298
Query: 298 --SKRKNQHIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKDI 355
+K+K +PYR+S LT LLKDSLGGN +TIMIA +SP+ V Y +T +TL+YANRAK+I
Sbjct: 299 TLAKKKQVFVPYRDSVLTWLLKDSLGGNSKTIMIATISPADVNYGETLSTLRYANRAKNI 358
Query: 356 KSSLKSNVLNVNNHITQYVKICNEQKAEILLLKEKLKAYEEQKAFTNENDQAKLMISNPQ 415
+ +N + + VK+ E +AEI LK L + +Q L+ S
Sbjct: 359 ---INKPTINEDAN----VKLIRELRAEIARLKTLLA----------QGNQIALLDSPTA 401
Query: 416 EKEIERFQEILNCLFQNREEIRQEYLKLEMLLKENELKSFYQQQ 459
E+ Q+ E R + L E K NE ++ ++Q
Sbjct: 402 LSMEEKLQQ---------NEARVQELTKEWTNKWNETQNILKEQ 436
Score = 40.8 bits (94), Expect = 0.006
Identities = 57/281 (20%), Positives = 122/281 (43%), Gaps = 37/281 (13%)
Query: 348 YANRAKDIKSSLKSNVLNVNNHITQYVKICNEQKAEILLLKEKLKAYEEQKAFTNENDQA 407
+ A ++ KS +L+ + + E + ++L L+ +Q+ + +
Sbjct: 553 HPKEAAKLREKRKSGLLSSFSLSMTDLSKSRENLSAVMLYNPGLEFERQQREELEKLESK 612
Query: 408 KLMISNPQEK------EIERFQEILNCLFQNREEIRQEYLKLEMLLKENELKSFYQQQCH 461
+ +I +EK E+ER Q+ + + E ++ + K E LK +SF+ + +
Sbjct: 613 RKLIEEMEEKQKSDKAELERMQQEVETQRKETEIVQLQIRKQEESLKR---RSFHIE--N 667
Query: 462 KQIEMMCSEDKVEKATGKRDHRLAMLKTRR---SYLEKRREEELKQFDENTNWLHRVEKE 518
K +++ ++K E+ + + + K R+ ++L R +EEL++ E N + ++
Sbjct: 668 KLKDLLAEKEKFEEERLREQQEIELQKKRQEEETFL--RVQEELQRLKELNN--NEKAEK 723
Query: 519 MGLLSQNGHIPKELKKDLHCHHLHLQNKDLKAQIRHMMDLACLQEQQHRQTEAVLNAL-- 576
+ + + KE KD L L+ K L+ Q + + L E+Q R+ + ++ L
Sbjct: 724 FQIFQELDQLQKE--KDEQYAKLELEKKRLEEQEKEQVMLVAHLEEQLREKQEMIQLLRR 781
Query: 577 ------------LPTLRKQYCTLKEAGLSNAAFESDFKEIE 605
L +R+ +KEA A + D +E+E
Sbjct: 782 GEVQWVEEEKRDLEGIRESLLRVKEA---RAGGDEDGEELE 819
>gi|83716024 kinesin family member 21B [Homo sapiens]
Length = 1624
Score = 233 bits (595), Expect = 5e-61
Identities = 162/439 (36%), Positives = 222/439 (50%), Gaps = 73/439 (16%)
Query: 7 DLCHHMKVVVRVRPENTKEKAAGFHKVVHVVDKHILVFDPKQEEVSFFHGKKTTNQNVIK 66
D C +KV VR+RP+ +KEK G H V P + +V
Sbjct: 6 DCC--VKVAVRIRPQLSKEKIEGCHICTSVT--------PGEPQVLL------------- 42
Query: 67 KQNKDLKFVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTM--- 123
KD F +D VFD + Q +++ ++ GYN TVLAYG TGAGKT+TM
Sbjct: 43 --GKDKAFTYDFVFDLDTWQEQIYSTCVSKLIEGCFEGYNATVLAYGQTGAGKTYTMGTG 100
Query: 124 ---LGSADEPGVMYLTMLHLYKCMDEIK----EEKICS----TAVSYLEVYNEQIRDLLV 172
S +E G++ + HL+ + E K E+ + + +LE+YNE+I DL
Sbjct: 101 FDMATSEEEQGIIPRAIAHLFGGIAERKRRAQEQGVAGPEFKVSAQFLELYNEEILDLFD 160
Query: 173 NS---------GPLAVREDTQKGVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNA 223
++ + + ED G+ G+T S EE++ L G +RT T MN
Sbjct: 161 STRDPDTRHRRSNIKIHEDANGGIYTTGVTSRLIHSQEELIQCLKQGALSRTTASTQMNV 220
Query: 224 TSSRSHAVFQIYLRQQDKTAS---INQNVR---------------IAKMSLIDLAGSERA 265
SSRSHA+F I+L Q +N+ V AK +DLAGSER
Sbjct: 221 QSSRSHAIFTIHLCQMRMCTQPDLVNEAVTGLPDGTPPSSEYETLTAKFHFVDLAGSERL 280
Query: 266 STSGAKGTRFVEGTNINRSLLALGNVINALADSKRKNQHIPYRNSKLTRLLKDSLGGNCQ 325
+GA G R EG +IN LLALGNVI+AL D +K H+PYR+SKLTRLL+DSLGGN Q
Sbjct: 281 KRTGATGERAKEGISINCGLLALGNVISALGDQSKKVVHVPYRDSKLTRLLQDSLGGNSQ 340
Query: 326 TIMIAAVSPSSVFYDDTYNTLKYANRAKDIKSSLKSNVLNVNNHITQYVKICNEQKAEIL 385
TIMIA VSPS + +T NTLKYANRA++IK+ + N + I+ +AEI
Sbjct: 341 TIMIACVSPSDRDFMETLNTLKYANRARNIKNKVVVNQDKTSQQISAL-------RAEIA 393
Query: 386 LLKEKLKAYEEQKAFTNEN 404
L+ +L Y+ K E+
Sbjct: 394 RLQMELMEYKAGKRVIGED 412
Score = 41.2 bits (95), Expect = 0.004
Identities = 50/230 (21%), Positives = 98/230 (42%), Gaps = 27/230 (11%)
Query: 412 SNPQEKEIERFQEI--LNCLFQNREEIRQEYLKLEMLLKENELKSFYQQQCHKQIEMMCS 469
S+P+EKE+ ++ L C + ++++ E + L+ LK Y+++ ++
Sbjct: 623 SDPEEKEVNFQADLADLTCEIEIKQKLIDELENSQRRLQT--LKHQYEEK------LILL 674
Query: 470 EDKVEKATGKRDHRLAMLKTRRSYLEKRR-------EEELKQFDENTNWLHRVEKEMG-L 521
++K+ +RD L L T Y E++ E+ L++ + + L +KE L
Sbjct: 675 QNKIRDTQLERDRVLQNLSTMECYTEEKANKIKADYEKRLREMNRDLQKLQAAQKEHARL 734
Query: 522 LSQNGHIPKELKKDLHCHHLHLQNKDLKAQIRHMMDLACLQEQQHRQTEAVLNALLPTLR 581
L +ELKK L + ++K +M ++Q+ R E N + L+
Sbjct: 735 LKNQSRYERELKK------LQAEVAEMKKAKVALMKQMREEQQRRRLVETKRNREIAQLK 788
Query: 582 KQYCTLKEAGLSNAAFESDFKEIEHLVERKKVVVWADQTAEQPKQNDLPG 631
K+ + A ES ++ E ++ RK V A + +P + G
Sbjct: 789 KEQ---RRQEFQIRALESQKRQQEMVLRRKTQEVSALRRLAKPMSERVAG 835
>gi|157738629 kinesin family member 13A isoform d [Homo sapiens]
Length = 1749
Score = 233 bits (594), Expect = 6e-61
Identities = 169/456 (37%), Positives = 249/456 (54%), Gaps = 46/456 (10%)
Query: 12 MKVVVRVRPENTKEKAAGFHKVVHVVDKHILVFDPKQEEVSFFHGKKTTNQNVIKKQNKD 71
+KV VRVRP N +E VV + ++ P N + + K
Sbjct: 6 VKVAVRVRPMNRRELELNTKCVVEMEGNQTVLHPPPS--------------NTKQGERKP 51
Query: 72 LK-FVFDAVF---DETST-----QSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHT 122
K F FD F DE++T Q VF+ + IL GYN + AYG TG+GK+ +
Sbjct: 52 PKVFAFDYCFWSMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFS 111
Query: 123 MLGSADEPGVMYLTMLHLYKCMD-EIKEEKICSTAVSYLEVYNEQIRDLLVNSGP---LA 178
M+G A++ G++ L+K + E E + VSY+E+YNE++RDLL G L
Sbjct: 112 MMGHAEQLGLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQSLK 171
Query: 179 VREDTQKGVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQ 238
VRE G V GL+ S E+I L+ GNK+RT T+MN SSRSHAVF I + Q
Sbjct: 172 VREHKVLGPYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQ 231
Query: 239 Q-DKTASINQNVRIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINALAD 297
S N +++K+SL+DLAGSER S +GA G R EG+NIN+SL LG VI++LAD
Sbjct: 232 TLYDLQSGNSGEKVSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLAD 291
Query: 298 S---KRKNQHIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKD 354
K K++ +PYR+S LT LLKD+LGGN QT MIA +SP++ Y++T +TL+YA+RAK
Sbjct: 292 QAAGKGKSKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRAKR 351
Query: 355 IKSSLKSNVLNVNNHITQYVKICNEQKAEILLLKEKLKAYEEQKA-----FTNENDQAKL 409
I + V+N + + K+ E + E+ L+E+L E KA E+++
Sbjct: 352 I---VNHAVVNEDPN----AKVIRELREEVEKLREQLSQAEAMKAPELKEKLEESEKLIK 404
Query: 410 MISNPQEKEIERFQEILNCLFQNREEIRQEYLKLEM 445
++ E+++ + +EI + + ++ + LEM
Sbjct: 405 ELTVTWEEKLRKTEEIAQ---ERQRQLESMGISLEM 437
>gi|157738627 kinesin family member 13A isoform c [Homo sapiens]
Length = 1757
Score = 233 bits (594), Expect = 6e-61
Identities = 169/456 (37%), Positives = 249/456 (54%), Gaps = 46/456 (10%)
Query: 12 MKVVVRVRPENTKEKAAGFHKVVHVVDKHILVFDPKQEEVSFFHGKKTTNQNVIKKQNKD 71
+KV VRVRP N +E VV + ++ P N + + K
Sbjct: 6 VKVAVRVRPMNRRELELNTKCVVEMEGNQTVLHPPPS--------------NTKQGERKP 51
Query: 72 LK-FVFDAVF---DETST-----QSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHT 122
K F FD F DE++T Q VF+ + IL GYN + AYG TG+GK+ +
Sbjct: 52 PKVFAFDYCFWSMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFS 111
Query: 123 MLGSADEPGVMYLTMLHLYKCMD-EIKEEKICSTAVSYLEVYNEQIRDLLVNSGP---LA 178
M+G A++ G++ L+K + E E + VSY+E+YNE++RDLL G L
Sbjct: 112 MMGHAEQLGLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQSLK 171
Query: 179 VREDTQKGVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQ 238
VRE G V GL+ S E+I L+ GNK+RT T+MN SSRSHAVF I + Q
Sbjct: 172 VREHKVLGPYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQ 231
Query: 239 Q-DKTASINQNVRIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINALAD 297
S N +++K+SL+DLAGSER S +GA G R EG+NIN+SL LG VI++LAD
Sbjct: 232 TLYDLQSGNSGEKVSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLAD 291
Query: 298 S---KRKNQHIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKD 354
K K++ +PYR+S LT LLKD+LGGN QT MIA +SP++ Y++T +TL+YA+RAK
Sbjct: 292 QAAGKGKSKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRAKR 351
Query: 355 IKSSLKSNVLNVNNHITQYVKICNEQKAEILLLKEKLKAYEEQKA-----FTNENDQAKL 409
I + V+N + + K+ E + E+ L+E+L E KA E+++
Sbjct: 352 I---VNHAVVNEDPN----AKVIRELREEVEKLREQLSQAEAMKAPELKEKLEESEKLIK 404
Query: 410 MISNPQEKEIERFQEILNCLFQNREEIRQEYLKLEM 445
++ E+++ + +EI + + ++ + LEM
Sbjct: 405 ELTVTWEEKLRKTEEIAQ---ERQRQLESMGISLEM 437
>gi|157738625 kinesin family member 13A isoform b [Homo sapiens]
Length = 1770
Score = 233 bits (594), Expect = 6e-61
Identities = 169/456 (37%), Positives = 249/456 (54%), Gaps = 46/456 (10%)
Query: 12 MKVVVRVRPENTKEKAAGFHKVVHVVDKHILVFDPKQEEVSFFHGKKTTNQNVIKKQNKD 71
+KV VRVRP N +E VV + ++ P N + + K
Sbjct: 6 VKVAVRVRPMNRRELELNTKCVVEMEGNQTVLHPPPS--------------NTKQGERKP 51
Query: 72 LK-FVFDAVF---DETST-----QSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHT 122
K F FD F DE++T Q VF+ + IL GYN + AYG TG+GK+ +
Sbjct: 52 PKVFAFDYCFWSMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFS 111
Query: 123 MLGSADEPGVMYLTMLHLYKCMD-EIKEEKICSTAVSYLEVYNEQIRDLLVNSGP---LA 178
M+G A++ G++ L+K + E E + VSY+E+YNE++RDLL G L
Sbjct: 112 MMGHAEQLGLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQSLK 171
Query: 179 VREDTQKGVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQ 238
VRE G V GL+ S E+I L+ GNK+RT T+MN SSRSHAVF I + Q
Sbjct: 172 VREHKVLGPYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQ 231
Query: 239 Q-DKTASINQNVRIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINALAD 297
S N +++K+SL+DLAGSER S +GA G R EG+NIN+SL LG VI++LAD
Sbjct: 232 TLYDLQSGNSGEKVSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLAD 291
Query: 298 S---KRKNQHIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKD 354
K K++ +PYR+S LT LLKD+LGGN QT MIA +SP++ Y++T +TL+YA+RAK
Sbjct: 292 QAAGKGKSKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRAKR 351
Query: 355 IKSSLKSNVLNVNNHITQYVKICNEQKAEILLLKEKLKAYEEQKA-----FTNENDQAKL 409
I + V+N + + K+ E + E+ L+E+L E KA E+++
Sbjct: 352 I---VNHAVVNEDPN----AKVIRELREEVEKLREQLSQAEAMKAPELKEKLEESEKLIK 404
Query: 410 MISNPQEKEIERFQEILNCLFQNREEIRQEYLKLEM 445
++ E+++ + +EI + + ++ + LEM
Sbjct: 405 ELTVTWEEKLRKTEEIAQ---ERQRQLESMGISLEM 437
>gi|157738621 kinesin family member 13A isoform a [Homo sapiens]
Length = 1805
Score = 233 bits (594), Expect = 6e-61
Identities = 169/456 (37%), Positives = 249/456 (54%), Gaps = 46/456 (10%)
Query: 12 MKVVVRVRPENTKEKAAGFHKVVHVVDKHILVFDPKQEEVSFFHGKKTTNQNVIKKQNKD 71
+KV VRVRP N +E VV + ++ P N + + K
Sbjct: 6 VKVAVRVRPMNRRELELNTKCVVEMEGNQTVLHPPPS--------------NTKQGERKP 51
Query: 72 LK-FVFDAVF---DETST-----QSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHT 122
K F FD F DE++T Q VF+ + IL GYN + AYG TG+GK+ +
Sbjct: 52 PKVFAFDYCFWSMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFS 111
Query: 123 MLGSADEPGVMYLTMLHLYKCMD-EIKEEKICSTAVSYLEVYNEQIRDLLVNSGP---LA 178
M+G A++ G++ L+K + E E + VSY+E+YNE++RDLL G L
Sbjct: 112 MMGHAEQLGLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQSLK 171
Query: 179 VREDTQKGVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQ 238
VRE G V GL+ S E+I L+ GNK+RT T+MN SSRSHAVF I + Q
Sbjct: 172 VREHKVLGPYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQ 231
Query: 239 Q-DKTASINQNVRIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINALAD 297
S N +++K+SL+DLAGSER S +GA G R EG+NIN+SL LG VI++LAD
Sbjct: 232 TLYDLQSGNSGEKVSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLAD 291
Query: 298 S---KRKNQHIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKD 354
K K++ +PYR+S LT LLKD+LGGN QT MIA +SP++ Y++T +TL+YA+RAK
Sbjct: 292 QAAGKGKSKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRAKR 351
Query: 355 IKSSLKSNVLNVNNHITQYVKICNEQKAEILLLKEKLKAYEEQKA-----FTNENDQAKL 409
I + V+N + + K+ E + E+ L+E+L E KA E+++
Sbjct: 352 I---VNHAVVNEDPN----AKVIRELREEVEKLREQLSQAEAMKAPELKEKLEESEKLIK 404
Query: 410 MISNPQEKEIERFQEILNCLFQNREEIRQEYLKLEM 445
++ E+++ + +EI + + ++ + LEM
Sbjct: 405 ELTVTWEEKLRKTEEIAQ---ERQRQLESMGISLEM 437
>gi|170784809 kinesin family member 17 isoform b [Homo sapiens]
Length = 1028
Score = 233 bits (594), Expect = 6e-61
Identities = 141/356 (39%), Positives = 201/356 (56%), Gaps = 24/356 (6%)
Query: 12 MKVVVRVRPENTKEKAAGFHKVVHVVDKHILVFDPKQEEVSFFHGKKTTNQNVIKKQNKD 71
+KVVVR RP N +E+ VV V D + + QN
Sbjct: 6 VKVVVRCRPMNQRERELRCQPVVTV--------DCARAQCCI--------QNPGAADEPP 49
Query: 72 LKFVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTMLGSADEP- 130
+F FD + +++ P++ GYN T+ AYG TG+GK+ TM G D P
Sbjct: 50 KQFTFDGAYHVDHVTEQIYNEIAYPLVEGVTEGYNGTIFAYGQTGSGKSFTMQGLPDPPS 109
Query: 131 --GVMYLTMLHLYKCMDEIKEEKICSTAVSYLEVYNEQIRDLLV--NSGPLAVREDTQKG 186
G++ H+++ + + K A SYLE+YNE +RDLL L ++E +KG
Sbjct: 110 QRGIIPRAFEHVFESVQCAENTKFLVRA-SYLEIYNEDVRDLLGADTKQKLELKEHPEKG 168
Query: 187 VVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQQDKTASIN 246
V V GL++H S + H+++ G KNR+ T MN SSRSH++F I +
Sbjct: 169 VYVKGLSMHTVHSVAQCEHIMETGWKNRSVGYTLMNKDSSRSHSIFTISIEMSAVDERGK 228
Query: 247 QNVRIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINALADSKRKNQHIP 306
++R K++L+DLAGSER S +GA G R E T IN SL ALGNVI+AL D + K H+P
Sbjct: 229 DHLRAGKLNLVDLAGSERQSKTGATGERLKEATKINLSLSALGNVISALVDGRCK--HVP 286
Query: 307 YRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKDIKSSLKSN 362
YR+SKLTRLL+DSLGGN +T+M+A +SP+ YD+T +TL+YANRAK+I++ + N
Sbjct: 287 YRDSKLTRLLQDSLGGNTKTLMVACLSPADNNYDETLSTLRYANRAKNIRNKPRIN 342
>gi|170784807 kinesin family member 17 isoform a [Homo sapiens]
Length = 1029
Score = 233 bits (594), Expect = 6e-61
Identities = 141/356 (39%), Positives = 201/356 (56%), Gaps = 24/356 (6%)
Query: 12 MKVVVRVRPENTKEKAAGFHKVVHVVDKHILVFDPKQEEVSFFHGKKTTNQNVIKKQNKD 71
+KVVVR RP N +E+ VV V D + + QN
Sbjct: 6 VKVVVRCRPMNQRERELRCQPVVTV--------DCARAQCCI--------QNPGAADEPP 49
Query: 72 LKFVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTMLGSADEP- 130
+F FD + +++ P++ GYN T+ AYG TG+GK+ TM G D P
Sbjct: 50 KQFTFDGAYHVDHVTEQIYNEIAYPLVEGVTEGYNGTIFAYGQTGSGKSFTMQGLPDPPS 109
Query: 131 --GVMYLTMLHLYKCMDEIKEEKICSTAVSYLEVYNEQIRDLLV--NSGPLAVREDTQKG 186
G++ H+++ + + K A SYLE+YNE +RDLL L ++E +KG
Sbjct: 110 QRGIIPRAFEHVFESVQCAENTKFLVRA-SYLEIYNEDVRDLLGADTKQKLELKEHPEKG 168
Query: 187 VVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQQDKTASIN 246
V V GL++H S + H+++ G KNR+ T MN SSRSH++F I +
Sbjct: 169 VYVKGLSMHTVHSVAQCEHIMETGWKNRSVGYTLMNKDSSRSHSIFTISIEMSAVDERGK 228
Query: 247 QNVRIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINALADSKRKNQHIP 306
++R K++L+DLAGSER S +GA G R E T IN SL ALGNVI+AL D + K H+P
Sbjct: 229 DHLRAGKLNLVDLAGSERQSKTGATGERLKEATKINLSLSALGNVISALVDGRCK--HVP 286
Query: 307 YRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKDIKSSLKSN 362
YR+SKLTRLL+DSLGGN +T+M+A +SP+ YD+T +TL+YANRAK+I++ + N
Sbjct: 287 YRDSKLTRLLQDSLGGNTKTLMVACLSPADNNYDETLSTLRYANRAKNIRNKPRIN 342
>gi|203096856 kinesin family member 7 [Homo sapiens]
Length = 1343
Score = 232 bits (592), Expect = 1e-60
Identities = 136/308 (44%), Positives = 186/308 (60%), Gaps = 17/308 (5%)
Query: 70 KDLKFVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTMLGSA-- 127
+D F F V E + Q V++ +P+L +F G+N TV AYG TG+GKT+TM G A
Sbjct: 51 RDRHFGFHVVLAEDAGQEAVYQACVQPLLEAFFEGFNATVFAYGQTGSGKTYTM-GEASV 109
Query: 128 -----DEPGVMYLTMLHLYKCMDEIKEEKICSTAVSYLEVYNEQIRDLL---VNSGPLAV 179
DE G++ M +K +DE + C VSYLEVY E+ RDLL S + +
Sbjct: 110 ASLLEDEQGIVPRAMAEAFKLIDE-NDLLDCLVHVSYLEVYKEEFRDLLEVGTASRDIQL 168
Query: 180 REDTQKGVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQQ 239
RED + VV+ G+ + +E+L LL+ GN R T +N SSRSH VF + L Q+
Sbjct: 169 REDERGNVVLCGVKEVDVEGLDEVLSLLEMGNAARHTGATHLNHLSSRSHTVFTVTLEQR 228
Query: 240 DKTAS-----INQNVRIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINA 294
+ S + ++K +DLAGSER +G+ G R E IN SLLALGNVI+A
Sbjct: 229 GRAPSRLPRPAPGQLLVSKFHFVDLAGSERVLKTGSTGERLKESIQINSSLLALGNVISA 288
Query: 295 LADSKRKNQHIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKD 354
L D +R+ HIPYR+SK+TR+LKDSLGGN +T+MIA VSPSS +D+T NTL YA+RA++
Sbjct: 289 LGDPQRRGSHIPYRDSKITRILKDSLGGNAKTVMIACVSPSSSDFDETLNTLNYASRAQN 348
Query: 355 IKSSLKSN 362
I++ N
Sbjct: 349 IRNRATVN 356
>gi|38569484 kinesin family member 21A [Homo sapiens]
Length = 1661
Score = 231 bits (590), Expect = 2e-60
Identities = 156/433 (36%), Positives = 217/433 (50%), Gaps = 71/433 (16%)
Query: 12 MKVVVRVRPENTKEKAAGFHKVVHVVDKHILVFDPKQEEVSFFHGKKTTNQNVIKKQNKD 71
++V VR+RP+ KEK G H V VF KD
Sbjct: 10 VRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVF-----------------------LGKD 46
Query: 72 LKFVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTMLGSAD--- 128
F FD VFD S Q +++ + ++ GYN TV AYG TGAGKT+TM D
Sbjct: 47 KAFTFDYVFDIDSQQEQIYIQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNI 106
Query: 129 ---EPGVMYLTMLHLYKCMDEIKEEKICS--------TAVSYLEVYNEQIRDLLVNS--- 174
E G++ + HL+K ++E K I + +LE+YNE++ DL +
Sbjct: 107 VEEELGIISRAVKHLFKSIEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDI 166
Query: 175 ------GPLAVREDTQKGVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRS 228
+ + ED+ G+ G+T + E++ L G +RT T MN SSRS
Sbjct: 167 DAKSKKSNIRIHEDSTGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRS 226
Query: 229 HAVFQIYLRQQ-----------------DKTASINQ-NVRIAKMSLIDLAGSERASTSGA 270
HA+F I++ Q ++A +N+ AK +DLAGSER +GA
Sbjct: 227 HAIFTIHVCQTRVCPQIDADNATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGA 286
Query: 271 KGTRFVEGTNINRSLLALGNVINALADSKRKNQHIPYRNSKLTRLLKDSLGGNCQTIMIA 330
G R EG +IN LLALGNVI+AL D ++ H+PYR+SKLTRLL+DSLGGN QTIMIA
Sbjct: 287 TGERAKEGISINCGLLALGNVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIA 346
Query: 331 AVSPSSVFYDDTYNTLKYANRAKDIKSSLKSNVLNVNNHITQYVKICNEQKAEILLLKEK 390
VSPS + +T NTLKYANRA++IK+ + N + I N ++EI L+ +
Sbjct: 347 CVSPSDRDFMETLNTLKYANRARNIKNKVMVNQDRASQQI-------NALRSEITRLQME 399
Query: 391 LKAYEEQKAFTNE 403
L Y+ K +E
Sbjct: 400 LMEYKTGKRIIDE 412
Score = 32.0 bits (71), Expect = 2.7
Identities = 29/137 (21%), Positives = 71/137 (51%), Gaps = 15/137 (10%)
Query: 380 QKAEILLLKEKLKAYEEQKAFTNEND-QAKLMISNPQEKEIERFQEILNCLFQNREEIRQ 438
++ ++L +++Y E+KA ++ + KL N + + ++ Q+ L +N+ + +
Sbjct: 682 ERDQVLQNLGSVESYSEEKAKKVRSEYEKKLQAMNKELQRLQAAQKEHARLLKNQSQYEK 741
Query: 439 EYLKLE---MLLKENELKSFYQQQCHKQIEMMCSEDK-------VEKATGKRDHRLAMLK 488
+ KL+ M +K+ +++ Q + +Q + +E + ++K KRDH+L +L+
Sbjct: 742 QLKKLQQDVMEMKKTKVRLMKQMK-EEQEKARLTESRRNREIAQLKKDQRKRDHQLRLLE 800
Query: 489 TRRSYLE---KRREEEL 502
++ E +R+ EE+
Sbjct: 801 AQKRNQEVVLRRKTEEV 817
>gi|13699824 kinesin family member 11 [Homo sapiens]
Length = 1056
Score = 231 bits (589), Expect = 2e-60
Identities = 182/577 (31%), Positives = 286/577 (49%), Gaps = 63/577 (10%)
Query: 5 EEDLCHHMKVVVRVRPENTKEKAAGFHKVVHVVDKHILVFDPKQEEVSFFHGKKTTNQNV 64
+E+ +++VVVR RP N E+ A H +V DP ++EVS G
Sbjct: 12 KEEKGKNIQVVVRCRPFNLAERKASAHSIVEC--------DPVRKEVSVRTGG------- 56
Query: 65 IKKQNKDLKFVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTML 124
+ ++ + FD VF ++ Q +V+ PIL + GYNCT+ AYG TG GKT TM
Sbjct: 57 LADKSSRKTYTFDMVFGASTKQIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTME 116
Query: 125 GSA---------DEP--GVMYLTMLHLYKCMDEIKEEKICSTAVSYLEVYNEQIRDLLVN 173
G ++P G++ T+ +++ + + E S VS LE+YNE++ DLL
Sbjct: 117 GERSPNEEYTWEEDPLAGIIPRTLHQIFEKLTDNGTE--FSVKVSLLEIYNEELFDLLNP 174
Query: 174 SGPLAVRED------TQKGVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSR 227
S ++ R ++GV++ GL + +E+ +L+ G RT T MNA SSR
Sbjct: 175 SSDVSERLQMFDDPRNKRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSR 234
Query: 228 SHAVFQIYLRQQDKTASINQNVRIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLA 287
SH+VF + + ++ T + V+I K++L+DLAGSE SGA R E NIN+SLL
Sbjct: 235 SHSVFSVTIHMKETTIDGEELVKIGKLNLVDLAGSENIGRSGAVDKRAREAGNINQSLLT 294
Query: 288 LGNVINALADSKRKNQHIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLK 347
LG VI AL + + H+PYR SKLTR+L+DSLGG +T +IA +SP+S+ ++T +TL+
Sbjct: 295 LGRVITALVE---RTPHVPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLE 351
Query: 348 YANRAKDIKSSLKSNVLNVNNHITQYVKICNEQKAEILLLKEKLKAYEEQKAFTNENDQA 407
YA+RAK+I N VN +T+ I E EI LK L A E+ +
Sbjct: 352 YAHRAKNI-----LNKPEVNQKLTKKALI-KEYTEEIERLKRDLAAAREKNGVYISEENF 405
Query: 408 KLMIS--NPQEKEIERFQEILNCLFQNREEIRQEYLKLEMLLKENELKSFYQQQCHKQIE 465
++M QE++I E + + + + + ++ +NEL QC ++
Sbjct: 406 RVMSGKLTVQEEQIVELIEKIGAVEEELNRVTELFMD-----NKNEL-----DQCKSDLQ 455
Query: 466 MMCSEDKVEKATGKRDHRLAMLKTRRSYLEKRREE-ELKQFDENTNWLHRVEKEMGLLSQ 524
E + T K + + Y+ E E K D + L+ VE+ +S
Sbjct: 456 NKTQE---LETTQKHLQETKLQLVKEEYITSALESTEEKLHDAASKLLNTVEETTKDVS- 511
Query: 525 NGHIPKELKKDLHCHHLHLQN---KDLKAQIRHMMDL 558
H + KK + H+ Q+ K+L + +M +L
Sbjct: 512 GLHSKLDRKKAVDQHNAEAQDIFGKNLNSLFNNMEEL 548
>gi|40254834 kinesin family member 1C [Homo sapiens]
Length = 1103
Score = 227 bits (579), Expect = 3e-59
Identities = 154/400 (38%), Positives = 227/400 (56%), Gaps = 44/400 (11%)
Query: 12 MKVVVRVRPENTKEKAAGFHKVVHVVDKHILVFDPKQEEVSFFHGKKTTNQNVIKKQNKD 71
+KV VRVRP N +E + VV + + +PKQ + +
Sbjct: 6 VKVAVRVRPFNARETSQDAKCVVSMQGNTTSIINPKQSK------------------DAP 47
Query: 72 LKFVFD-AVFDETST-------QSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTM 123
F FD + + TST Q +V+ + +L GYN + AYG TGAGK++TM
Sbjct: 48 KSFTFDYSYWSHTSTEDPQFASQQQVYRDIGEEMLLHAFEGYNVCIFAYGQTGAGKSYTM 107
Query: 124 LGSAD--EPGVMYLTMLHLYKCMDEIKEEKIC-STAVSYLEVYNEQIRDLL--VNSGPLA 178
+G + + G++ L+ + E + ++ S VSY+E+Y E++RDLL + G L
Sbjct: 108 MGRQEPGQQGIVPQLCEDLFSRVSENQSAQLSYSVEVSYMEIYCERVRDLLNPKSRGSLR 167
Query: 179 VREDTQKGVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQ 238
VRE G V L+ S +I L+D GNK RT T+MN TSSRSHAVF I Q
Sbjct: 168 VREHPILGPYVQDLSKLAVTSYADIADLMDCGNKARTVAATNMNETSSRSHAVFTIVFTQ 227
Query: 239 Q--DKTASINQNVRIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINALA 296
+ D+ ++ +++K+SL+DLAGSERA +SGA+G R EG NIN+SL LG VI+ALA
Sbjct: 228 RCHDQLTGLDSE-KVSKISLVDLAGSERADSSGARGMRLKEGANINKSLTTLGKVISALA 286
Query: 297 D---SKRKNQHIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAK 353
D KRK+ IPYR+S LT LLK++LGGN +T MIAA+SP+ + Y++T +TL+YA+R K
Sbjct: 287 DMQSKKRKSDFIPYRDSVLTWLLKENLGGNSRTAMIAALSPADINYEETLSTLRYADRTK 346
Query: 354 DIKSSLKSNVLNVNNHITQYVKICNEQKAEILLLKEKLKA 393
I+ + ++N + + ++ E + E+ L+E L A
Sbjct: 347 QIRCNA---IINEDPN----ARLIRELQEEVARLRELLMA 379
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 222 bits (566), Expect = 1e-57
Identities = 151/438 (34%), Positives = 238/438 (54%), Gaps = 41/438 (9%)
Query: 14 VVVRVRPENTKEKAAGFHKVVHVVDKHILVFDPKQEEVSFFHGKKTTNQNVIKKQNKDLK 73
V VRVRP N++E++ G E + + K T+ NVI + +
Sbjct: 9 VCVRVRPLNSREESLG--------------------ETAQVYWK--TDNNVIYQVDGSKS 46
Query: 74 FVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTMLGSADEPGVM 133
F FD VF T V+E PI+ S + GYN T+ AYG T +GKT+TM+GS D GV+
Sbjct: 47 FNFDRVFHGNETTKNVYEEIAAPIIDSAIQGYNGTIFAYGQTASGKTYTMMGSEDHLGVI 106
Query: 134 YLTMLHLYKCMDEIKEEKICSTAVSYLEVYNEQIRDLLVNS---GPLAVREDTQKGVVVH 190
+ +++ + + + + VSY+E+YNE I DLL + PL +RED + V V
Sbjct: 107 PRAIHDIFQKIKKFPDREFL-LRVSYMEIYNETITDLLCGTQKMKPLIIREDVNRNVYVA 165
Query: 191 GLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYL--RQQDKTASINQN 248
LT +SE L + G K+R T MN SSRSH +F++ L R++ + ++ +
Sbjct: 166 DLTEEVVYTSEMALKWITKGEKSRHYGETKMNQRSSRSHTIFRMILESREKGEPSNCEGS 225
Query: 249 VRIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINALADSKRKNQHIPYR 308
V+++ ++L+DLAGSERA+ +GA G R EG NINRSL LG VI L+D + I YR
Sbjct: 226 VKVSHLNLVDLAGSERAAQTGAAGVRLKEGCNINRSLFILGQVIKKLSDG-QVGGFINYR 284
Query: 309 NSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKDIKSSLKSNVLNVNN 368
+SKLTR+L++SLGGN +T +I ++P V +D+T L++A+ AK +K++ N ++ +
Sbjct: 285 DSKLTRILQNSLGGNAKTRIICTITP--VSFDETLTALQFASTAKYMKNTPYVNEVSTDE 342
Query: 369 HITQYVKICNEQKAEILLLKEKLKAYE-EQKAFTNENDQAKLMISNP---QEKEIERFQE 424
+ + EI+ LK++L+ E +A E DQ ++ Q+ + E+ +
Sbjct: 343 ------ALLKRYRKEIMDLKKQLEEVSLETRAQAMEKDQLAQLLEEKDLLQKVQNEKIEN 396
Query: 425 ILNCLFQNREEIRQEYLK 442
+ L + Q+ LK
Sbjct: 397 LTRMLVTSSSLTLQQELK 414
Score = 44.3 bits (103), Expect = 5e-04
Identities = 50/228 (21%), Positives = 99/228 (43%), Gaps = 22/228 (9%)
Query: 388 KEKLKAYEEQKAFTNENDQAKLMISNPQEKEIERFQE--ILNCLFQNREEIRQEYLKLEM 445
KEK Q+ +E+DQ K I K +E +E + +C + +EE E L++ +
Sbjct: 1442 KEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINE-LRVNL 1500
Query: 446 LLKENELKSFYQQQCHKQIEMMCSEDKVEKATGKRDHRLAMLKTRRSYLEKRREEELKQF 505
KE E+ + KQ+E + DK++ + + ++ + + ELKQF
Sbjct: 1501 SEKETEISTI-----QKQLEAI--NDKLQNKIQEIYEKEEQFNIKQISEVQEKVNELKQF 1553
Query: 506 DENTNWLHRVEKEMGLLSQNG---HIPKELKKDLHCHHLHLQNKDLKAQIRHMMDLACLQ 562
E HR K+ L S + L++ + ++ K+ +++ + + +
Sbjct: 1554 KE-----HRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIE--R 1606
Query: 563 EQQHRQTEAVLNALLPTLRKQYCTLKEAGLSNAAFESDFKEIEHLVER 610
+Q T+ ++ + + K+Y LK ++ + EIEHL E+
Sbjct: 1607 DQLKENTKEIVAKMKESQEKEYQFLKMTAVNET--QEKMCEIEHLKEQ 1652
Score = 43.9 bits (102), Expect = 7e-04
Identities = 68/311 (21%), Positives = 140/311 (45%), Gaps = 43/311 (13%)
Query: 347 KYANRAKDIK-SSLKSNVLNVNNHITQY---VKICNEQKAEILLLKEKLKAYEEQKAFTN 402
K +AKD S++S +L + N + + ++I ++K E+ ++E L+ +Q
Sbjct: 1554 KEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQLKENT 1613
Query: 403 ENDQAKLM--------------ISNPQEK--EIERFQEILNCLFQNREEIRQEYLKLEML 446
+ AK+ ++ QEK EIE +E N E I E ++L +
Sbjct: 1614 KEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENIETENIRLTQI 1673
Query: 447 LKEN--ELKSFYQQQCHKQIEMMCSEDKVEKATGKRDHRLAMLKTRRSYLEKRREEE--- 501
L EN E++S +++ + + KVE+ K + R + + LEK+ E +
Sbjct: 1674 LHENLEEMRSVTKER--DDLRSVEETLKVERDQLKENLRETITRD----LEKQEELKIVH 1727
Query: 502 --LKQFDENTNWLHRVEKEMGLLSQNGHIPKELKKDLHCHHLHLQNKDLKAQIRHMMDLA 559
LK+ E ++K G++S+ + ++KDL + L+ +DLK I+ + +A
Sbjct: 1728 MHLKEHQET------IDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLK--IQEELRIA 1779
Query: 560 CLQEQQHRQTEAVLNALLPTLRKQYCTL-KEAGLSNAAFESDFKEIEHLVERKKVVVWAD 618
+ ++ ++T L ++ + + K+ SNA + +E++ E + + + D
Sbjct: 1780 HMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELK-ANEHQLITLKKD 1838
Query: 619 QTAEQPKQNDL 629
Q K +++
Sbjct: 1839 VNETQKKVSEM 1849
Score = 31.6 bits (70), Expect = 3.5
Identities = 40/213 (18%), Positives = 86/213 (40%), Gaps = 43/213 (20%)
Query: 341 DTYNTLKYANRAKDIKSSLKSNVLNV------NNHITQYVKICNEQKAEILLLKEKLKAY 394
D T K + + +K +K L + N ++ Q + E+ ++ ++ L+
Sbjct: 1838 DVNETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQKLHENLEEMKSVMKERDNLRRV 1897
Query: 395 EEQKAFTNENDQAKLMISNPQEKEIERFQEILNCLFQNREEIRQEYLKLEMLLKENE--L 452
EE E DQ K + + +++ EI+QE ML KE++ +
Sbjct: 1898 EETLKL--ERDQLKESLQETKARDL---------------EIQQELKTARMLSKEHKETV 1940
Query: 453 KSFYQQQCHKQIEMMCSEDKVEKATGKRDHRLAMLKTRRSYLEKRREEELKQFDENTNWL 512
++ K I++ + ++K+ + ++ L +++E +L + E+ N
Sbjct: 1941 DKLREKISEKTIQISDIQKDLDKSKDELQKKIQEL--------QKKELQLLRVKEDVNMS 1992
Query: 513 HRVEKEMGLLSQNGHIPKELKKDLHCHHLHLQN 545
H+ EM ++LKK +L +Q+
Sbjct: 1993 HKKINEM----------EQLKKQFEAQNLSMQS 2015
Score = 30.4 bits (67), Expect = 7.7
Identities = 43/202 (21%), Positives = 89/202 (44%), Gaps = 25/202 (12%)
Query: 355 IKSSLKSNVLNVNNHITQYVKICNEQKAEILLLKEKLKAY-EEQKAFTNE---------N 404
+K+S ++ N+ +IT K I LL+E ++ E F+N N
Sbjct: 431 MKNSNYADQFNIPTNITT-----KTHKLSINLLREIDESVCSESDVFSNTLDTLSEIEWN 485
Query: 405 DQAKLMISNPQEKEIERFQEILNCLFQNREEIRQEYLKLEMLLKE-NELKSF--YQQQCH 461
KL+ E E+ + + L + E++R E ++E+ LKE N+L F +++
Sbjct: 486 PATKLLNQENIESELNSLRADYDNLVLDYEQLRTEKEEMELKLKEKNDLDEFEALERKTK 545
Query: 462 KQIEMMCSED-----KVEKATGKRDHRLAMLKTRRSYLEKRREEELKQFDE--NTNWLHR 514
K EM + + K + L + + L + +E+++K+ E ++ L
Sbjct: 546 KDQEMQLIHEISNLKNLVKHAEVYNQDLENELSSKVELLREKEDQIKKLQEYIDSQKLEN 605
Query: 515 VEKEMGLLSQNGHIPKELKKDL 536
++ ++ ++ PK++K+ L
Sbjct: 606 IKMDLSYSLESIEDPKQMKQTL 627
>gi|4758650 kinesin family member 5C [Homo sapiens]
Length = 957
Score = 221 bits (564), Expect = 2e-57
Identities = 195/591 (32%), Positives = 284/591 (48%), Gaps = 63/591 (10%)
Query: 12 MKVVVRVRPENTKEKAAGFHKVVHVVDKHILVFDPKQEEVSFFHGKKTTNQNVIKKQNKD 71
+KV+ R RP N E G DK I PK F G +T V+ Q K
Sbjct: 9 IKVMCRFRPLNEAEILRG--------DKFI----PK------FKGDET----VVIGQGKP 46
Query: 72 LKFVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTMLGSADEPG 131
+VFD V +TQ +V+ K I++ L GYN T+ AYG T +GKTHTM G +P
Sbjct: 47 --YVFDRVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQ 104
Query: 132 VMYLTML-------HLYKCMDEIKEEKICSTAVSYLEVYNEQIRDLL-VNSGPLAVREDT 183
+M + H+Y MDE E I VSY E+Y ++IRDLL V+ LAV ED
Sbjct: 105 LMGIIPRIAHDIFDHIYS-MDENLEFHI---KVSYFEIYLDKIRDLLDVSKTNLAVHEDK 160
Query: 184 QKGVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQQDKTA 243
+ V G T S EE++ ++D G NR T+MN SSRSH++F I ++Q++
Sbjct: 161 NRVPYVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVET 220
Query: 244 SINQNVRIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINALADSKRKNQ 303
+ K+ L+DLAGSE+ S +GA+G E NIN+SL ALGNVI+ALA+ +
Sbjct: 221 EKKLS---GKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKT-- 275
Query: 304 HIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKDIKSSLKSNV 363
H+PYR+SK+TR+L+DSLGGNC+T ++ SPS +T +TL + RAK IK N
Sbjct: 276 HVPYRDSKMTRILQDSLGGNCRTTIVICCSPSVFNEAETKSTLMFGQRAKTIK-----NT 330
Query: 364 LNVNNHIT--QYVKICNEQKAEILLLKEKLKAYE-EQKAFTN-ENDQAKLMISNPQEKEI 419
++VN +T ++ K ++K + LK ++ E E + N E IS +K +
Sbjct: 331 VSVNLELTAEEWKKKYEKEKEKNKTLKNVIQHLEMELNRWRNGEAVPEDEQISAKDQKNL 390
Query: 420 ERFQEILNCLFQNREEIRQEYLKLEMLLKENELKSFYQQQCHKQIEMMCSEDKVEKATGK 479
E + N + E + E+ S Y+Q K E+ EK +
Sbjct: 391 EPCDN--TPIIDNIAPVVAGISTEEKEKYDEEISSLYRQLDDKDDEINQQSQLAEKLKQQ 448
Query: 480 R-DHRLAMLKTRRSYLEKRREEELKQFDENTNWLHRVEKEMGLLSQNGHIPKELKKDLH- 537
D + TRR Y EK +EE + EN V++ + L + + +++
Sbjct: 449 MLDQDELLASTRRDY-EKIQEELTRLQIENEAAKDEVKEVLQALEELAVNYDQKSQEVED 507
Query: 538 --------CHHLHLQNKDLKAQIRHMMDLACLQEQQHRQTEAVLNALLPTL 580
L + L R + L L Q ++ +LN LL L
Sbjct: 508 KTRANEQLTDELAQKTTTLTTTQRELSQLQELSNHQKKRATEILNLLLKDL 558
>gi|9910266 kinesin family member 15 [Homo sapiens]
Length = 1388
Score = 220 bits (561), Expect = 4e-57
Identities = 172/492 (34%), Positives = 250/492 (50%), Gaps = 49/492 (9%)
Query: 74 FVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTMLGSADEP--- 130
F FD V D +TQ VF K I+ S ++GYN T+ AYG TG+GKT TM+G ++
Sbjct: 70 FTFDHVADVDTTQESVFATVAKSIVESCMSGYNGTIFAYGQTGSGKTFTMMGPSESDNFS 129
Query: 131 ----GVMYLTMLHLYKCMDEIKEE----KICSTAVSYLEVYNEQIRDLLVN-SGPLAVRE 181
GV+ + +L+ +D KE+ K S++E+YNEQI DLL + S L +RE
Sbjct: 130 HNLRGVIPRSFEYLFSLIDREKEKAGAGKSFLCKCSFIEIYNEQIYDLLDSASAGLYLRE 189
Query: 182 DTQKGVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQQDK 241
+KGV V G S+ E +L G +NR T MN SSRSHAVF I + +K
Sbjct: 190 HIKKGVFVVGAVEQVVTSAAEAYQVLSGGWRNRRVASTSMNRESSRSHAVFTITIESMEK 249
Query: 242 TASINQNVRIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINALAD-SKR 300
+ I N+R + ++L+DLAGSER + A+G R E NINRSL LG VI AL D
Sbjct: 250 SNEI-VNIRTSLLNLVDLAGSERQKDTHAEGMRLKEAGNINRSLSCLGQVITALVDVGNG 308
Query: 301 KNQHIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKDIKSSLK 360
K +H+ YR+SKLT LL+DSLGGN +T +IA V P S + +T +TL +A RAK IK+
Sbjct: 309 KQRHVCYRDSKLTFLLRDSLGGNAKTAIIANVHPGSRCFGETLSTLNFAQRAKLIKNKAV 368
Query: 361 SNVLNVNNHITQYVKICNEQKAEILLLKEKLKAYEEQKAFTNENDQAKLMISNPQEKEIE 420
N N ++ +AE+ LKE+L + A ++ L + +E
Sbjct: 369 VNEDTQGN--------VSQLQAEVKRLKEQL----AELASGQTPPESFLTRDKKKTNYME 416
Query: 421 RFQEILNCLFQNREEIRQEYLKLEMLLKENELKSFYQQQCHKQIEMMCSEDKVEKATGKR 480
FQE + F+ E+ ++ ++ L++ LK Q +K I + ED++ +
Sbjct: 417 YFQEAM-LFFKKSEQEKKSLIEKVTQLEDLTLKKEKFIQSNKMI-VKFREDQIIR----- 469
Query: 481 DHRLAMLKTRRSYLEKRREEELKQF--DENTNWLHRVEKEMGLL-SQNGHIPKELKKDLH 537
LEK +E F +E L + E+ L Q H P+ K +
Sbjct: 470 -------------LEKLHKESRGGFLPEEQDRLLSELRNEIQTLREQIEHHPRVAKYAME 516
Query: 538 CHHLHLQNKDLK 549
H L +N+ L+
Sbjct: 517 NHSLREENRRLR 528
Score = 32.3 bits (72), Expect = 2.0
Identities = 49/250 (19%), Positives = 103/250 (41%), Gaps = 31/250 (12%)
Query: 282 NRSLLALGNVINALADSKRKNQHIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDD 341
N + L +V+++ A+ + + P+ + L +LL+ Q I S +S+ +
Sbjct: 1122 NFKMRQLEHVMDSAAEDPQSPKTPPHFQTHLAKLLETQE----QEIEDGRASKTSLEH-- 1175
Query: 342 TYNTLKYANRAKDIKSSLKSNVLNVNNHITQYVKICNEQKAEI---LLLKEKLKAYEEQK 398
+ N +++K++ +L + + + + E + I LL+ +L + QK
Sbjct: 1176 ---LVTKLNEDREVKNA---EILRMKEQLREMENLRLESQQLIEKNWLLQGQLDDIKRQK 1229
Query: 399 AFTNENDQAKLMISNPQEKEIERFQEILNCLFQNREEIRQEYLKLEMLLKENELKSFYQQ 458
+++N + N QE+ I +E + + + EML + +L+
Sbjct: 1230 ENSDQNHPDNQQLKNEQEESI-------------KERLAKSKIVEEMLKMKADLEEVQSA 1276
Query: 459 QCHKQIEMMCSEDKVEKATGKRDHRLAMLKTRRSYLEKRREEELKQFDENTNWLHRVEKE 518
+K++E + D+VE+ + RS LE+ EE + E +VE
Sbjct: 1277 LYNKEMECLRMTDEVERTQTLESKAFQEKEQLRSKLEEMYEERERTSQEMEMLRKQVE-- 1334
Query: 519 MGLLSQNGHI 528
L +NG +
Sbjct: 1335 -CLAEENGKL 1343
>gi|45446749 kinesin family member 5A [Homo sapiens]
Length = 1032
Score = 218 bits (556), Expect = 2e-56
Identities = 185/577 (32%), Positives = 281/577 (48%), Gaps = 85/577 (14%)
Query: 12 MKVVVRVRPENTKEKAAGFHKVVHVVDKHILVFDPKQEEVSFFHGKKTTNQNVIKKQNKD 71
+KV+ R RP N E G DK I +F Q + S G K
Sbjct: 10 IKVLCRFRPLNQAEILRG--------DKFIPIF---QGDDSVVIGGKP------------ 46
Query: 72 LKFVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTMLGSADEPG 131
+VFD VF +TQ +V+ I++ L GYN T+ AYG T +GKTHTM G +P
Sbjct: 47 --YVFDRVFPPNTTQEQVYHACAMQIVKDVLAGYNGTIFAYGQTSSGKTHTMEGKLHDPQ 104
Query: 132 VMYLT-------MLHLYKCMDEIKEEKICSTAVSYLEVYNEQIRDLL-VNSGPLAVREDT 183
+M + H+Y MDE E I VSY E+Y ++IRDLL V L+V ED
Sbjct: 105 LMGIIPRIARDIFNHIYS-MDENLEFHI---KVSYFEIYLDKIRDLLDVTKTNLSVHEDK 160
Query: 184 QKGVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQQDKTA 243
+ V G T S EEIL ++D G NR T+MN SSRSH++F I ++Q++
Sbjct: 161 NRVPFVKGCTERFVSSPEEILDVIDEGKSNRHVAVTNMNEHSSRSHSIFLINIKQENMET 220
Query: 244 SINQNVRIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINALADSKRKNQ 303
+ K+ L+DLAGSE+ S +GA+G E NIN+SL ALGNVI+ALA+ +
Sbjct: 221 EQKLS---GKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKS-- 275
Query: 304 HIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKDIKSSLKSNV 363
++PYR+SK+TR+L+DSLGGNC+T M SPSS +T +TL + RAK IK++ N+
Sbjct: 276 YVPYRDSKMTRILQDSLGGNCRTTMFICCSPSSYNDAETKSTLMFGQRAKTIKNTASVNL 335
Query: 364 -LNVNNHITQYVKICNEQKAE---ILLLKEKLKAYE-------------EQKAF------ 400
L +Y K + KA+ I L+ +L + E+ A
Sbjct: 336 ELTAEQWKKKYEKEKEKTKAQKETIAKLEAELSRWRNGENVPETERLAGEEAALGAELCE 395
Query: 401 -TNENDQAKLMI---SNPQEKEIERFQEILNCLFQNREEIRQ-----EYLKLEMLLKENE 451
T ND + +++ ++K E + + L +EI Q E LK +ML +E
Sbjct: 396 ETPVNDNSSIVVRIAPEERQKYEEEIRRLYKQLDDKDDEINQQSQLIEKLKQQMLDQEEL 455
Query: 452 LKS-------FYQQQCHKQIEMMCSEDKVEKATGKRDHRLAMLKTRRSYLEKRREEE--- 501
L S ++ H Q E ++D+V++ + + +E++ ++
Sbjct: 456 LVSTRGDNEKVQRELSHLQSENDAAKDEVKEVLQALEELAVNYDQKSQEVEEKSQQNQLL 515
Query: 502 LKQFDENTNWLHRVEKEMGLLSQ-NGHIPKELKKDLH 537
+ + + + +E E+ L + +GH K + + L+
Sbjct: 516 VDELSQKVATMLSLESELQRLQEVSGHQRKRIAEVLN 552
>gi|4758648 kinesin family member 5B [Homo sapiens]
Length = 963
Score = 216 bits (549), Expect = 1e-55
Identities = 167/501 (33%), Positives = 255/501 (50%), Gaps = 79/501 (15%)
Query: 11 HMKVVVRVRPENTKEKAAGFHKVVHVVDKHILVFDPKQEEVSFFHGKKTTNQNVIKKQNK 70
++KV+ R RP N E G DK+I + F G+ T VI +
Sbjct: 8 NIKVMCRFRPLNESEVNRG--------DKYI----------AKFQGEDTV---VIASK-- 44
Query: 71 DLKFVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTMLGSADEP 130
+ FD VF +++Q +V+ K I++ L GYN T+ AYG T +GKTHTM G +P
Sbjct: 45 --PYAFDRVFQSSTSQEQVYNDCAKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDP 102
Query: 131 ---GVMYLTMLHLYKCMDEIKEEKICSTAVSYLEVYNEQIRDLL-VNSGPLAVREDTQKG 186
G++ + ++ + + E VSY E+Y ++IRDLL V+ L+V ED +
Sbjct: 103 EGMGIIPRIVQDIFNYIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLSVHEDKNRV 162
Query: 187 VVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQQDKTASIN 246
V G T S +E++ +D G NR T+MN SSRSH++F I ++Q++
Sbjct: 163 PYVKGCTERFVCSPDEVMDTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQTEQK 222
Query: 247 QNVRIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINALADSKRKNQHIP 306
+ K+ L+DLAGSE+ S +GA+G E NIN+SL ALGNVI+ALA+ + ++P
Sbjct: 223 LS---GKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEG---STYVP 276
Query: 307 YRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKDIKSSLKSNVLNV 366
YR+SK+TR+L+DSLGGNC+T ++ SPSS +T +TL + RAK IK+++ +NV
Sbjct: 277 YRDSKMTRILQDSLGGNCRTTIVICCSPSSYNESETKSTLLFGQRAKTIKNTV---CVNV 333
Query: 367 NNHITQYVKICNEQKAEILLL-----------------------------KEKLKAYEEQ 397
Q+ K ++K + +L K L+A+
Sbjct: 334 ELTAEQWKKKYEKEKEKNKILRNTIQWLENELNRWRNGETVPIDEQFDKEKANLEAFTVD 393
Query: 398 KAFTNENDQ---AKLMISNPQEKEIERFQEILNCLFQ----NREEIRQ-----EYLKLEM 445
K T ND+ A +I N + E + +E + L++ EEI Q E LK +M
Sbjct: 394 KDITLTNDKPATAIGVIGNFTDAERRKCEEEIAKLYKQLDDKDEEINQQSQLVEKLKTQM 453
Query: 446 LLKENELKSFYQQQCHKQIEM 466
L +E L S + Q + Q E+
Sbjct: 454 LDQEELLASTRRDQDNMQAEL 474
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.129 0.365
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,276,762
Number of Sequences: 37866
Number of extensions: 1536272
Number of successful extensions: 7554
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 83
Number of HSP's successfully gapped in prelim test: 359
Number of HSP's that attempted gapping in prelim test: 6554
Number of HSP's gapped (non-prelim): 1073
length of query: 898
length of database: 18,247,518
effective HSP length: 111
effective length of query: 787
effective length of database: 14,044,392
effective search space: 11052936504
effective search space used: 11052936504
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.