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Search of human proteins with 148596957
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|148596957 myosin binding protein C, cardiac [Homo sapiens]
(1274 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|148596957 myosin binding protein C, cardiac [Homo sapiens] 2578 0.0
gi|133908641 myosin binding protein C, fast type [Homo sapiens] 1224 0.0
gi|46049110 myosin binding protein C, slow type isoform 4 [Homo ... 1150 0.0
gi|46049125 myosin binding protein C, slow type isoform 2 [Homo ... 1147 0.0
gi|45976288 myosin binding protein C, slow type isoform 1 [Homo ... 1147 0.0
gi|46049119 myosin binding protein C, slow type isoform 3 [Homo ... 1139 0.0
gi|55956914 myosin binding protein H [Homo sapiens] 434 e-121
gi|194018539 myosin binding protein H-like [Homo sapiens] 344 4e-94
gi|110349719 titin isoform N2-A [Homo sapiens] 286 9e-77
gi|110349717 titin isoform novex-2 [Homo sapiens] 286 9e-77
gi|110349713 titin isoform novex-1 [Homo sapiens] 286 9e-77
gi|110349715 titin isoform N2-B [Homo sapiens] 286 9e-77
gi|253970427 immunoglobulin superfamily, member 22 [Homo sapiens] 278 2e-74
gi|148839296 immunoglobulin-like and fibronectin type III domain... 238 4e-62
gi|58331253 obscurin, cytoskeletal calmodulin and titin-interact... 151 4e-36
gi|148833506 obscurin, cytoskeletal calmodulin and titin-interac... 151 4e-36
gi|140560917 myomesin 1 isoform b [Homo sapiens] 135 2e-31
gi|156104903 myomesin 2 [Homo sapiens] 126 1e-28
gi|144226847 obscurin-like 1 [Homo sapiens] 124 4e-28
gi|155969693 myomesin family, member 3 [Homo sapiens] 119 2e-26
gi|110349721 titin isoform novex-3 [Homo sapiens] 118 4e-26
gi|140560919 myomesin 1 isoform a [Homo sapiens] 115 2e-25
gi|118572606 hemicentin 1 [Homo sapiens] 111 4e-24
gi|193083163 roundabout, axon guidance receptor, homolog 2 isofo... 108 2e-23
gi|61888896 roundabout, axon guidance receptor, homolog 2 isofor... 108 2e-23
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens] 108 4e-23
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] 108 4e-23
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens] 108 4e-23
gi|116008194 myosin light chain kinase isoform 3A [Homo sapiens] 107 9e-23
gi|116008192 myosin light chain kinase isoform 1 [Homo sapiens] 107 9e-23
>gi|148596957 myosin binding protein C, cardiac [Homo sapiens]
Length = 1274
Score = 2578 bits (6681), Expect = 0.0
Identities = 1274/1274 (100%), Positives = 1274/1274 (100%)
Query: 1 MPEPGKKPVSAFSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATE 60
MPEPGKKPVSAFSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATE
Sbjct: 1 MPEPGKKPVSAFSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATE 60
Query: 61 GTRHTLTVREVGPADQGSYAVIAGSSKVKFDLKVIEAEKAEPMLAPAPAPAEATGAPGEA 120
GTRHTLTVREVGPADQGSYAVIAGSSKVKFDLKVIEAEKAEPMLAPAPAPAEATGAPGEA
Sbjct: 61 GTRHTLTVREVGPADQGSYAVIAGSSKVKFDLKVIEAEKAEPMLAPAPAPAEATGAPGEA 120
Query: 121 PAPAAELGESAPSPKGSSSAALNGPTPGAPDDPIGLFVMRPQDGEVTVGGSITFSARVAG 180
PAPAAELGESAPSPKGSSSAALNGPTPGAPDDPIGLFVMRPQDGEVTVGGSITFSARVAG
Sbjct: 121 PAPAAELGESAPSPKGSSSAALNGPTPGAPDDPIGLFVMRPQDGEVTVGGSITFSARVAG 180
Query: 181 ASLLKPPVVKWFKGKWVDLSSKVGQHLQLHDSYDRASKVYLFELHITDAQPAFTGSYRCE 240
ASLLKPPVVKWFKGKWVDLSSKVGQHLQLHDSYDRASKVYLFELHITDAQPAFTGSYRCE
Sbjct: 181 ASLLKPPVVKWFKGKWVDLSSKVGQHLQLHDSYDRASKVYLFELHITDAQPAFTGSYRCE 240
Query: 241 VSTKDKFDCSNFNLTVHEAMGTGDLDLLSAFRRTSLAGGGRRISDSHEDTGILDFSSLLK 300
VSTKDKFDCSNFNLTVHEAMGTGDLDLLSAFRRTSLAGGGRRISDSHEDTGILDFSSLLK
Sbjct: 241 VSTKDKFDCSNFNLTVHEAMGTGDLDLLSAFRRTSLAGGGRRISDSHEDTGILDFSSLLK 300
Query: 301 KRDSFRTPRDSKLEAPAEEDVWEILRQAPPSEYERIAFQYGVTDLRGMLKRLKGMRRDEK 360
KRDSFRTPRDSKLEAPAEEDVWEILRQAPPSEYERIAFQYGVTDLRGMLKRLKGMRRDEK
Sbjct: 301 KRDSFRTPRDSKLEAPAEEDVWEILRQAPPSEYERIAFQYGVTDLRGMLKRLKGMRRDEK 360
Query: 361 KSTAFQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRT 420
KSTAFQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRT
Sbjct: 361 KSTAFQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRT 420
Query: 421 LTISQCSLADDAAYQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEE 480
LTISQCSLADDAAYQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEE
Sbjct: 421 LTISQCSLADDAAYQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEE 480
Query: 481 GAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIV 540
GAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIV
Sbjct: 481 GAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIV 540
Query: 541 QEKKLEVYQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHK 600
QEKKLEVYQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHK
Sbjct: 541 QEKKLEVYQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHK 600
Query: 601 LTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIV 660
LTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIV
Sbjct: 601 LTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIV 660
Query: 661 VVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCE 720
VVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCE
Sbjct: 661 VVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCE 720
Query: 721 TEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPKI 780
TEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPKI
Sbjct: 721 TEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPKI 780
Query: 781 SNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGV 840
SNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGV
Sbjct: 781 SNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGV 840
Query: 841 VYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGG 900
VYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGG
Sbjct: 841 VYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGG 900
Query: 901 LDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTE 960
LDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTE
Sbjct: 901 LDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTE 960
Query: 961 PVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVS 1020
PVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVS
Sbjct: 961 PVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVS 1020
Query: 1021 IRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGL 1080
IRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGL
Sbjct: 1021 IRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGL 1080
Query: 1081 NVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVF 1140
NVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVF
Sbjct: 1081 NVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVF 1140
Query: 1141 SQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAML 1200
SQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAML
Sbjct: 1141 SQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAML 1200
Query: 1201 CCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQG 1260
CCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQG
Sbjct: 1201 CCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQG 1260
Query: 1261 EARCECRLEVRVPQ 1274
EARCECRLEVRVPQ
Sbjct: 1261 EARCECRLEVRVPQ 1274
>gi|133908641 myosin binding protein C, fast type [Homo sapiens]
Length = 1141
Score = 1224 bits (3167), Expect = 0.0
Identities = 628/1186 (52%), Positives = 795/1186 (67%), Gaps = 76/1186 (6%)
Query: 98 EKAEPMLAPAPAPAEATGAPGEAPAPAAELGESAPSPKGSSSAALNGPTPGAPDDPIGLF 157
++A P APA AP E AP E +P AE +P G+F
Sbjct: 23 KEAPPKEAPAEAPKE---APPEDQSPTAE-------------------------EPTGVF 54
Query: 158 VMRPQDGEVTVGGSITFSARVAGASLLKPPVVKWFKGKWVDLSSKVGQHLQLHDSYDRAS 217
+ +P V G A+V G L P +KWFKGKW++L SK G +S++ AS
Sbjct: 55 LKKPDSVSVETGKDAVVVAKVNGKELPDKPTIKWFKGKWLELGSKSGARFSFKESHNSAS 114
Query: 218 KVYLFELHITDAQPAFTGSYRCEVSTKDKFDCSNFNLTVHEAMGTGDLDLLSAFRRTSLA 277
VY ELHI G YR EV KD D FN+ V L +F+RTS
Sbjct: 115 NVYTVELHIGKVVLGDRGYYRLEVKAKDTCDSCGFNIDVEAPRQDASGQSLESFKRTS-- 172
Query: 278 GGGRRISDSHEDTGILDFSSLLKKRDSFRTPR------DSKLEAPAEEDVWEILRQAPPS 331
+ G LDFS LLKKR+ + D L P E +WE+L+ A S
Sbjct: 173 ------EKKSDTAGELDFSGLLKKREVVEEEKKKKKKDDDDLGIPPE--IWELLKGAKKS 224
Query: 332 EYERIAFQYGVTDLRGMLKRLKGMRRDEKKSTAFQKKLEPAYQVSKGHKIRLTVELADHD 391
EYE+IAFQYG+TDLRGMLKRLK + + KKS AF KKL+PAYQV +G+KI+L VE++D D
Sbjct: 225 EYEKIAFQYGITDLRGMLKRLKKAKVEVKKSAAFTKKLDPAYQVDRGNKIKLMVEISDPD 284
Query: 392 AEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCSTELFVKE 451
+KW KNGQEI+ S SKY+FE++G KR LTI++C+LADDAAY+ V EKC TELFVKE
Sbjct: 285 LTLKWFKNGQEIKPS-SKYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTELFVKE 343
Query: 452 PPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFK--YRFKKDGQR 509
PPVLI PLEDQ V VG RVE EVSEEGAQV W+KDGVELTRE++FK YRFKKDG+R
Sbjct: 344 PPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKR 403
Query: 510 HHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFKCEVS 569
H LI ++ + ED G Y + T+GGQ AELIV+EK+LEV Q IADL V A +QAVFKCEVS
Sbjct: 404 HILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVS 463
Query: 570 DENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKL 629
DE V G W KNG E+ P RI +SH+GR HKL IDDV P DE DY+FVP+G+A +LSAKL
Sbjct: 464 DEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKL 523
Query: 630 HFMEVKIDFVPRQEPPKIHLDCPGRIPD-TIVVVAGNKLRLDVPISGDPAPTVIWQKAIT 688
+F+E+K+++VP+QEPPKIHLDC G+ + IVVVAGNKLRLDV I+G+P P W K
Sbjct: 524 NFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLK--- 580
Query: 689 QGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGV 748
GD ++ TEGR R+E D S F +E A++EDEG
Sbjct: 581 -----------------GD--------EVFTTTEGRTRIEKRVDCSSFVIESAQREDEGR 615
Query: 749 YTVTVKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYIL 808
YT+ V NPVGED ++ ++V+DVPD P A +I++VGED + WEPP YDGG+P+ GY++
Sbjct: 616 YTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLV 675
Query: 809 ERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIG 868
ERKKK S RWM+LNF++ E ++E+ +MIEG++YEMRV+AVNAIG+S+PS ++PFMPI
Sbjct: 676 ERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIA 735
Query: 869 PPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTS 928
P SEP HL VEDV+DTT +LKWRPP R+GAGG+DGY VEYC EG EWV A E
Sbjct: 736 PTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCG 795
Query: 929 ILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVG 988
VK+LPTGAR+LFRV N+AG P T +PVT++EI + P+++LPRHLRQT +KVG
Sbjct: 796 FTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVG 855
Query: 989 EPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVR 1048
E +NL++PFQGKPRPQV WTK G PL V +R S DT+ F+R A R SG Y+++V+
Sbjct: 856 EQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQ 915
Query: 1049 IENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKK 1108
IENM+D AT+ ++VV+K PP ++ V + WG N +EW+ P+D GN+E+ GY VQKADKK
Sbjct: 916 IENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKK 975
Query: 1109 TMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYE 1168
TMEWF V E R T C V +LI+GN YYFRV+++N+ G SD +K I + GIT++
Sbjct: 976 TMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFK 1035
Query: 1169 PPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFR 1228
P YK DF AP F PL++R V+AGY+A L CAVRG PKPK+ W KN +++ ED +F
Sbjct: 1036 PFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFL 1095
Query: 1229 MFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVRVPQ 1274
+ + QGVLTL IR+P PFD G Y CRA N GEA EC+LEVRVPQ
Sbjct: 1096 ITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEVRVPQ 1141
Score = 43.1 bits (100), Expect = 0.002
Identities = 26/89 (29%), Positives = 42/89 (47%), Gaps = 7/89 (7%)
Query: 21 VAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYA 80
V A AVF+ E V +W + G ++ S + ++ G H L + +V P D+G Y
Sbjct: 450 VKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYT 509
Query: 81 VIAG------SSKVKF-DLKVIEAEKAEP 102
+ S+K+ F ++KV K EP
Sbjct: 510 FVPDGYALSLSAKLNFLEIKVEYVPKQEP 538
Score = 38.9 bits (89), Expect = 0.032
Identities = 28/103 (27%), Positives = 45/103 (43%), Gaps = 5/103 (4%)
Query: 7 KPVSAFSKK-PRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHT 65
K +AF+KK + +V G+ E + ++W + G +I S+KY G +
Sbjct: 253 KKSAAFTKKLDPAYQVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRI 312
Query: 66 LTVREVGPADQGSYAVIAGSSKVKFDLKVIEAEKAEPMLAPAP 108
LT+ + AD +Y V K +L V K P+L P
Sbjct: 313 LTINKCTLADDAAYEVAVKDEKCFTELFV----KEPPVLIVTP 351
Score = 37.7 bits (86), Expect = 0.071
Identities = 21/83 (25%), Positives = 36/83 (43%), Gaps = 4/83 (4%)
Query: 20 EVAAGSPAVFEAETERAGVKVRWQRGGSDISASN----KYGLATEGTRHTLTVREVGPAD 75
+V G E G +V W + G +++ + +Y +G RH L +V D
Sbjct: 356 QVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQED 415
Query: 76 QGSYAVIAGSSKVKFDLKVIEAE 98
+G Y VI + + +L V E +
Sbjct: 416 RGRYQVITNGGQCEAELIVEEKQ 438
>gi|46049110 myosin binding protein C, slow type isoform 4 [Homo
sapiens]
Length = 1123
Score = 1150 bits (2974), Expect = 0.0
Identities = 583/1186 (49%), Positives = 775/1186 (65%), Gaps = 77/1186 (6%)
Query: 96 EAEKAEPMLAPAPAPAEATGAPGEAPAPAAELGES-------APSPKGSSSAALNGPTPG 148
E K E PAPAP P E P+ E G + +P G A N
Sbjct: 3 EPTKKEENEVPAPAP------PPEEPSKEKEAGTTPAKDWTLVETPPGEEQAKQN----- 51
Query: 149 APDDPIGLFVMRPQDGEVTVGGSITFSARVAGASLLKPPVVKWFKGKWVDLSSKVGQHLQ 208
A LF+ +PQ G V VG ITF A+V LL+ P +KWFKGKW+DL+SK G+HLQ
Sbjct: 52 ANSQLSILFIEKPQGGTVKVGEDITFIAKVKAEDLLRKPTIKWFKGKWMDLASKAGKHLQ 111
Query: 209 LHDSYDRASKVYLFELHITDAQPAFTGSYRCEVSTKDKFDCSNFNLTVHEAMGTG-DLDL 267
L ++++R S+VY FE+ I A+ F G+YRCEV+ KDKFD +F+L VHE+ GT ++D+
Sbjct: 112 LKETFERHSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSFDLEVHESTGTTPNIDI 171
Query: 268 LSAFRRTSLAGGGRRISDSHEDTGILDFSSLLKKRDSFRTPRDSKLEAPAEEDVWEILRQ 327
SAF+R+ + ED G LDFS LLK+R+ + E + DVWE+L+
Sbjct: 172 RSAFKRSG---------EGQEDAGELDFSGLLKRREV------KQQEEEPQVDVWELLKN 216
Query: 328 APPSEYERIAFQYGVTDLRGMLKRLKGMRRDEKKSTAFQKKLEPAYQVSKGHKIRLTVEL 387
A PSEYE+IAFQYG+TDLRGMLKRLK MRR+EKKS AF K L+PAYQV KG ++R VEL
Sbjct: 217 AKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVEL 276
Query: 388 ADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCSTEL 447
AD EVKW KNGQEI+ S +KYIFE G +R L I+ C + DD+ Y G EKCSTEL
Sbjct: 277 ADPKLEVKWYKNGQEIRPS-TKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTEL 335
Query: 448 FVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKKDG 507
FV+EPP+++T+ LED G+RVE ECEVSE+ A VKW K+G E+ +YR + +G
Sbjct: 336 FVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEG 395
Query: 508 QRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFKCE 567
++H LII A DA Y++ T+GGQ+ A+L V K L++ + D V + KCE
Sbjct: 396 KKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCE 455
Query: 568 VSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSA 627
+S EN+ G W KNG + R+KV H GR+HKL I + DE DY F P+ + L A
Sbjct: 456 IS-ENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPA 514
Query: 628 KLHFMEVKIDFVPRQEPPKIHLDCPGRIPD-TIVVVAGNKLRLDVPISGDPAPTVIWQKA 686
K+H ++ PPKI LD G D T+ V+AGNKLRL++PISG+P P +W +
Sbjct: 515 KVHVID----------PPKIILD--GLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSR- 561
Query: 687 ITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDE 746
GD K + E GR+R E+ D S ++ AE++D
Sbjct: 562 -------------------GD--------KAIMEGSGRIRTESYPDSSTLVIDIAERDDS 594
Query: 747 GVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGY 806
GVY + +KN GE ++ VKV+D PD P AP ++ VG+D C + WEPPAYDGG PILGY
Sbjct: 595 GVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGY 654
Query: 807 ILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMP 866
+ERKKK+S RWMRLNFDL +E + E ++MIEGV YE+R++AVNAIG+S+PS S+PF+P
Sbjct: 655 FIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVP 714
Query: 867 IGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEH 926
+ S PT L V+ V+DTTV+++WRPP+ +GA GLDGY +EYC EG +W+ A + L +
Sbjct: 715 LAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDK 774
Query: 927 TSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKK 986
T + LPT A++ RV+A N AG P ++P+ V+EI++ P++++PRHL+QT ++
Sbjct: 775 TKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRR 834
Query: 987 VGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVT 1046
VGE VNL+IPFQGKPRP++TW K+G + +++IRNS TDTI+FIR A R HSG Y +
Sbjct: 835 VGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQ 894
Query: 1047 VRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKAD 1106
V+++ + A++ +Q++D+P PPQ +++ D WG NVAL W PP+D GN + GYT+QKAD
Sbjct: 895 VKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKAD 954
Query: 1107 KKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGIT 1166
KK+MEWFTV+EHY RT + EL+IGN YYFRVFS+NM G S+ A TKE I R G
Sbjct: 955 KKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKI 1014
Query: 1167 YEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDAR 1226
Y+ P Y+ DFSEAP FTQPLVN IAGY A L C+VRG+PKPKI+W KN + + +D R
Sbjct: 1015 YKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPR 1074
Query: 1227 FRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVRV 1272
+RMFS QGV TLEIRKP P+DGG Y C+A N G EC+LEV+V
Sbjct: 1075 YRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1120
Score = 39.3 bits (90), Expect = 0.024
Identities = 33/131 (25%), Positives = 51/131 (38%), Gaps = 6/131 (4%)
Query: 6 KKPVSAFSK-KPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRH 64
+K +AF+K + +V G F E ++V+W + G +I S KY +G +
Sbjct: 248 EKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQR 307
Query: 65 TLTVREVGPADQGSYAVIAGSSKVKFDLKVIEAEKAEPMLAPAPAPAEATGAPGEAPAPA 124
L + D Y V AG K +L V EP + + T GE
Sbjct: 308 ILFINNCQMTDDSEYYVTAGDEKCSTELFV-----REPPIMVTKQLEDTTAYCGERVELE 362
Query: 125 AELGESAPSPK 135
E+ E + K
Sbjct: 363 CEVSEDDANVK 373
Score = 39.3 bits (90), Expect = 0.024
Identities = 23/97 (23%), Positives = 41/97 (42%), Gaps = 6/97 (6%)
Query: 6 KKPVSAFSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDI--SASNKYGLATEGTR 63
++P +K+ G E E V+W + G +I ++Y + EG +
Sbjct: 338 REPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKK 397
Query: 64 HTLTVREVGPADQGSYAVIA----GSSKVKFDLKVIE 96
H L + AD Y+V+ S+K+ DLK ++
Sbjct: 398 HILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLK 434
>gi|46049125 myosin binding protein C, slow type isoform 2 [Homo
sapiens]
Length = 1148
Score = 1147 bits (2966), Expect = 0.0
Identities = 582/1189 (48%), Positives = 775/1189 (65%), Gaps = 78/1189 (6%)
Query: 105 APAPAPAEATGAPGEAPAPAAELGESAPS---PKGSSSAALNGPTPG--APDDPIG---- 155
APAP P E + PA + E +P P G S AL + P G
Sbjct: 14 APAPPPEEPSKEKEAGTTPAKDEEEVSPPSALPPGLGSRALERKDSDWTLVETPPGEEQA 73
Query: 156 ----------LFVMRPQDGEVTVGGSITFSARVAGASLLKPPVVKWFKGKWVDLSSKVGQ 205
LF+ +PQ G V VG ITF A+V LL+ P +KWFKGKW+DL+SK G+
Sbjct: 74 KQNANSQLSILFIEKPQGGTVKVGEDITFIAKVKAEDLLRKPTIKWFKGKWMDLASKAGK 133
Query: 206 HLQLHDSYDRASKVYLFELHITDAQPAFTGSYRCEVSTKDKFDCSNFNLTVHEAMGTG-D 264
HLQL ++++R S+VY FE+ I A+ F G+YRCEV+ KDKFD +F+L VHE+ GT +
Sbjct: 134 HLQLKETFERHSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSFDLEVHESTGTTPN 193
Query: 265 LDLLSAFRRTSLAGGGRRISDSHEDTGILDFSSLLKKRDSFRTPRDSKLEAPAEEDVWEI 324
+D+ SAF+R+ + ED G LDFS LLK+R+ + E + DVWE+
Sbjct: 194 IDIRSAFKRSG---------EGQEDAGELDFSGLLKRREV------KQQEEEPQVDVWEL 238
Query: 325 LRQAPPSEYERIAFQYGVTDLRGMLKRLKGMRRDEKKSTAFQKKLEPAYQVSKGHKIRLT 384
L+ A PSEYE+IAFQYG+TDLRGMLKRLK MRR+EKKS AF K L+PAYQV KG ++R
Sbjct: 239 LKNAKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFV 298
Query: 385 VELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCS 444
VELAD EVKW KNGQEI+ S +KYIFE G +R L I+ C + DD+ Y G EKCS
Sbjct: 299 VELADPKLEVKWYKNGQEIRPS-TKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCS 357
Query: 445 TELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFK 504
TELFV+EPP+++T+ LED G+RVE ECEVSE+ A VKW K+G E+ +YR +
Sbjct: 358 TELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIR 417
Query: 505 KDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVF 564
+G++H LII A DA Y++ T+GGQ+ A+L V K L++ + D V +
Sbjct: 418 VEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICL 477
Query: 565 KCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACN 624
KCE+S EN+ G W KNG + R+KV H GR+HKL I + DE DY F P+ +
Sbjct: 478 KCEIS-ENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVT 536
Query: 625 LSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPD-TIVVVAGNKLRLDVPISGDPAPTVIW 683
L AK+H ++ PPKI LD G D T+ V+AGNKLRL++PISG+P P +W
Sbjct: 537 LPAKVHVID----------PPKIILD--GLDADNTVTVIAGNKLRLEIPISGEPPPKAMW 584
Query: 684 QKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEK 743
+ GD K + E GR+R E+ D S ++ AE+
Sbjct: 585 SR--------------------GD--------KAIMEGSGRIRTESYPDSSTLVIDIAER 616
Query: 744 EDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPI 803
+D GVY + +KN GE ++ VKV+D PD P AP ++ VG+D C + WEPPAYDGG PI
Sbjct: 617 DDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPI 676
Query: 804 LGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQP 863
LGY +ERKKK+S RWMRLNFDL +E + E ++MIEGV YE+R++AVNAIG+S+PS S+P
Sbjct: 677 LGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRP 736
Query: 864 FMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGL 923
F+P+ S PT L V+ V+DTTV+++WRPP+ +GA GLDGY +EYC EG +W+ A + L
Sbjct: 737 FVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDL 796
Query: 924 TEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTI 983
+ T + LPT A++ RV+A N AG P ++P+ V+EI++ P++++PRHL+QT
Sbjct: 797 IDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTY 856
Query: 984 QKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTY 1043
++VGE VNL+IPFQGKPRP++TW K+G + +++IRNS TDTI+FIR A R HSG Y
Sbjct: 857 IRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKY 916
Query: 1044 QVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQ 1103
+ V+++ + A++ +Q++D+P PPQ +++ D WG NVAL W PP+D GN + GYT+Q
Sbjct: 917 DLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQ 976
Query: 1104 KADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRP 1163
KADKK+MEWFTV+EHY RT + EL+IGN YYFRVFS+NM G S+ A TKE I R
Sbjct: 977 KADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARD 1036
Query: 1164 GITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGE 1223
G Y+ P Y+ DFSEAP FTQPLVN IAGY A L C+VRG+PKPKI+W KN + + +
Sbjct: 1037 GKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVD 1096
Query: 1224 DARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVRV 1272
D R+RMFS QGV TLEIRKP P+DGG Y C+A N G EC+LEV+V
Sbjct: 1097 DPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1145
Score = 39.3 bits (90), Expect = 0.024
Identities = 33/131 (25%), Positives = 51/131 (38%), Gaps = 6/131 (4%)
Query: 6 KKPVSAFSK-KPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRH 64
+K +AF+K + +V G F E ++V+W + G +I S KY +G +
Sbjct: 273 EKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQR 332
Query: 65 TLTVREVGPADQGSYAVIAGSSKVKFDLKVIEAEKAEPMLAPAPAPAEATGAPGEAPAPA 124
L + D Y V AG K +L V EP + + T GE
Sbjct: 333 ILFINNCQMTDDSEYYVTAGDEKCSTELFV-----REPPIMVTKQLEDTTAYCGERVELE 387
Query: 125 AELGESAPSPK 135
E+ E + K
Sbjct: 388 CEVSEDDANVK 398
Score = 39.3 bits (90), Expect = 0.024
Identities = 23/97 (23%), Positives = 41/97 (42%), Gaps = 6/97 (6%)
Query: 6 KKPVSAFSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDI--SASNKYGLATEGTR 63
++P +K+ G E E V+W + G +I ++Y + EG +
Sbjct: 363 REPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKK 422
Query: 64 HTLTVREVGPADQGSYAVIA----GSSKVKFDLKVIE 96
H L + AD Y+V+ S+K+ DLK ++
Sbjct: 423 HILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLK 459
>gi|45976288 myosin binding protein C, slow type isoform 1 [Homo
sapiens]
Length = 1171
Score = 1147 bits (2966), Expect = 0.0
Identities = 582/1189 (48%), Positives = 775/1189 (65%), Gaps = 78/1189 (6%)
Query: 105 APAPAPAEATGAPGEAPAPAAELGESAPS---PKGSSSAALNGPTPG--APDDPIG---- 155
APAP P E + PA + E +P P G S AL + P G
Sbjct: 14 APAPPPEEPSKEKEAGTTPAKDEEEVSPPSALPPGLGSRALERKDSDWTLVETPPGEEQA 73
Query: 156 ----------LFVMRPQDGEVTVGGSITFSARVAGASLLKPPVVKWFKGKWVDLSSKVGQ 205
LF+ +PQ G V VG ITF A+V LL+ P +KWFKGKW+DL+SK G+
Sbjct: 74 KQNANSQLSILFIEKPQGGTVKVGEDITFIAKVKAEDLLRKPTIKWFKGKWMDLASKAGK 133
Query: 206 HLQLHDSYDRASKVYLFELHITDAQPAFTGSYRCEVSTKDKFDCSNFNLTVHEAMGTG-D 264
HLQL ++++R S+VY FE+ I A+ F G+YRCEV+ KDKFD +F+L VHE+ GT +
Sbjct: 134 HLQLKETFERHSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSFDLEVHESTGTTPN 193
Query: 265 LDLLSAFRRTSLAGGGRRISDSHEDTGILDFSSLLKKRDSFRTPRDSKLEAPAEEDVWEI 324
+D+ SAF+R+ + ED G LDFS LLK+R+ + E + DVWE+
Sbjct: 194 IDIRSAFKRSG---------EGQEDAGELDFSGLLKRREV------KQQEEEPQVDVWEL 238
Query: 325 LRQAPPSEYERIAFQYGVTDLRGMLKRLKGMRRDEKKSTAFQKKLEPAYQVSKGHKIRLT 384
L+ A PSEYE+IAFQYG+TDLRGMLKRLK MRR+EKKS AF K L+PAYQV KG ++R
Sbjct: 239 LKNAKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFV 298
Query: 385 VELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCS 444
VELAD EVKW KNGQEI+ S +KYIFE G +R L I+ C + DD+ Y G EKCS
Sbjct: 299 VELADPKLEVKWYKNGQEIRPS-TKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCS 357
Query: 445 TELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFK 504
TELFV+EPP+++T+ LED G+RVE ECEVSE+ A VKW K+G E+ +YR +
Sbjct: 358 TELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIR 417
Query: 505 KDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVF 564
+G++H LII A DA Y++ T+GGQ+ A+L V K L++ + D V +
Sbjct: 418 VEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICL 477
Query: 565 KCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACN 624
KCE+S EN+ G W KNG + R+KV H GR+HKL I + DE DY F P+ +
Sbjct: 478 KCEIS-ENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVT 536
Query: 625 LSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPD-TIVVVAGNKLRLDVPISGDPAPTVIW 683
L AK+H ++ PPKI LD G D T+ V+AGNKLRL++PISG+P P +W
Sbjct: 537 LPAKVHVID----------PPKIILD--GLDADNTVTVIAGNKLRLEIPISGEPPPKAMW 584
Query: 684 QKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEK 743
+ GD K + E GR+R E+ D S ++ AE+
Sbjct: 585 SR--------------------GD--------KAIMEGSGRIRTESYPDSSTLVIDIAER 616
Query: 744 EDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPI 803
+D GVY + +KN GE ++ VKV+D PD P AP ++ VG+D C + WEPPAYDGG PI
Sbjct: 617 DDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPI 676
Query: 804 LGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQP 863
LGY +ERKKK+S RWMRLNFDL +E + E ++MIEGV YE+R++AVNAIG+S+PS S+P
Sbjct: 677 LGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRP 736
Query: 864 FMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGL 923
F+P+ S PT L V+ V+DTTV+++WRPP+ +GA GLDGY +EYC EG +W+ A + L
Sbjct: 737 FVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDL 796
Query: 924 TEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTI 983
+ T + LPT A++ RV+A N AG P ++P+ V+EI++ P++++PRHL+QT
Sbjct: 797 IDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTY 856
Query: 984 QKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTY 1043
++VGE VNL+IPFQGKPRP++TW K+G + +++IRNS TDTI+FIR A R HSG Y
Sbjct: 857 IRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKY 916
Query: 1044 QVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQ 1103
+ V+++ + A++ +Q++D+P PPQ +++ D WG NVAL W PP+D GN + GYT+Q
Sbjct: 917 DLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQ 976
Query: 1104 KADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRP 1163
KADKK+MEWFTV+EHY RT + EL+IGN YYFRVFS+NM G S+ A TKE I R
Sbjct: 977 KADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARD 1036
Query: 1164 GITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGE 1223
G Y+ P Y+ DFSEAP FTQPLVN IAGY A L C+VRG+PKPKI+W KN + + +
Sbjct: 1037 GKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVD 1096
Query: 1224 DARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVRV 1272
D R+RMFS QGV TLEIRKP P+DGG Y C+A N G EC+LEV+V
Sbjct: 1097 DPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1145
Score = 39.3 bits (90), Expect = 0.024
Identities = 33/131 (25%), Positives = 51/131 (38%), Gaps = 6/131 (4%)
Query: 6 KKPVSAFSK-KPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRH 64
+K +AF+K + +V G F E ++V+W + G +I S KY +G +
Sbjct: 273 EKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQR 332
Query: 65 TLTVREVGPADQGSYAVIAGSSKVKFDLKVIEAEKAEPMLAPAPAPAEATGAPGEAPAPA 124
L + D Y V AG K +L V EP + + T GE
Sbjct: 333 ILFINNCQMTDDSEYYVTAGDEKCSTELFV-----REPPIMVTKQLEDTTAYCGERVELE 387
Query: 125 AELGESAPSPK 135
E+ E + K
Sbjct: 388 CEVSEDDANVK 398
Score = 39.3 bits (90), Expect = 0.024
Identities = 23/97 (23%), Positives = 41/97 (42%), Gaps = 6/97 (6%)
Query: 6 KKPVSAFSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDI--SASNKYGLATEGTR 63
++P +K+ G E E V+W + G +I ++Y + EG +
Sbjct: 363 REPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKK 422
Query: 64 HTLTVREVGPADQGSYAVIA----GSSKVKFDLKVIE 96
H L + AD Y+V+ S+K+ DLK ++
Sbjct: 423 HILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLK 459
>gi|46049119 myosin binding protein C, slow type isoform 3 [Homo
sapiens]
Length = 1141
Score = 1139 bits (2946), Expect = 0.0
Identities = 583/1204 (48%), Positives = 776/1204 (64%), Gaps = 95/1204 (7%)
Query: 96 EAEKAEPMLAPAPAPAEATGAPGEAPAPAAELGES-------APSPKGSSSAALNGPTPG 148
E K E PAPAP P E P+ E G + +P G A N
Sbjct: 3 EPTKKEENEVPAPAP------PPEEPSKEKEAGTTPAKDWTLVETPPGEEQAKQN----- 51
Query: 149 APDDPIGLFVMRPQDGEVTVGGSITFSARVAGASLLKPPVVKWFKGKWVDLSSKVGQHLQ 208
A LF+ +PQ G V VG ITF A+V LL+ P +KWFKGKW+DL+SK G+HLQ
Sbjct: 52 ANSQLSILFIEKPQGGTVKVGEDITFIAKVKAEDLLRKPTIKWFKGKWMDLASKAGKHLQ 111
Query: 209 LHDSYDRASKVYLFELHITDAQPAFTGSYRCEVSTKDKFDCSNFNLTVHEAMGTG-DLDL 267
L ++++R S+VY FE+ I A+ F G+YRCEV+ KDKFD +F+L VHE+ GT ++D+
Sbjct: 112 LKETFERHSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSFDLEVHESTGTTPNIDI 171
Query: 268 LSAFRRTSLAGGGRRISDSHEDTGILDFSSLLKKRDSFRTPRDSKLEAPAEEDVWEILRQ 327
SAF+R+ + ED G LDFS LLK+R+ + E + DVWE+L+
Sbjct: 172 RSAFKRSG---------EGQEDAGELDFSGLLKRREV------KQQEEEPQVDVWELLKN 216
Query: 328 APPSEYERIAFQYGVTDLRGMLKRLKGMRRDEKKSTAFQKKLEPAYQVSKGHKIRLTVEL 387
A PSEYE+IAFQYG+TDLRGMLKRLK MRR+EKKS AF K L+PAYQV KG ++R VEL
Sbjct: 217 AKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVEL 276
Query: 388 ADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCSTEL 447
AD EVKW KNGQEI+ S +KYIFE G +R L I+ C + DD+ Y G EKCSTEL
Sbjct: 277 ADPKLEVKWYKNGQEIRPS-TKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTEL 335
Query: 448 FVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKKDG 507
FV+EPP+++T+ LED G+RVE ECEVSE+ A VKW K+G E+ +YR + +G
Sbjct: 336 FVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEG 395
Query: 508 QRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFKCE 567
++H LII A DA Y++ T+GGQ+ A+L V K L++ + D V + KCE
Sbjct: 396 KKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCE 455
Query: 568 VSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSA 627
+S EN+ G W KNG + R+KV H GR+HKL I + DE DY F P+ + L A
Sbjct: 456 IS-ENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPA 514
Query: 628 KLHFMEVKIDFVPRQEPPKIHLDCPGRIPD-TIVVVAGNKLRLDVPISGDPAPTVIWQKA 686
K+H ++ PPKI LD G D T+ V+AGNKLRL++PISG+P P +W +
Sbjct: 515 KVHVID----------PPKIILD--GLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSR- 561
Query: 687 ITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDE 746
GD K + E GR+R E+ D S ++ AE++D
Sbjct: 562 -------------------GD--------KAIMEGSGRIRTESYPDSSTLVIDIAERDDS 594
Query: 747 GVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGY 806
GVY + +KN GE ++ VKV+D PD P AP ++ VG+D C + WEPPAYDGG PILGY
Sbjct: 595 GVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGY 654
Query: 807 ILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMP 866
+ERKKK+S RWMRLNFDL +E + E ++MIEGV YE+R++AVNAIG+S+PS S+PF+P
Sbjct: 655 FIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVP 714
Query: 867 IGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCS------------ 914
+ S PT L V+ V+DTTV+++WRPP+ +GA GLDGY +EYC EG +
Sbjct: 715 LAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAA 774
Query: 915 ------EWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEIL 968
+W+ A + L + T + LPT A++ RV+A N AG P ++P+ V+EI+
Sbjct: 775 YDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEII 834
Query: 969 QRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDT 1028
+ P++++PRHL+QT ++VGE VNL+IPFQGKPRP++TW K+G + +++IRNS TDT
Sbjct: 835 EPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDT 894
Query: 1029 ILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKP 1088
I+FIR A R HSG Y + V+++ + A++ +Q++D+P PPQ +++ D WG NVAL W P
Sbjct: 895 IIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTP 954
Query: 1089 PQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFS 1148
P+D GN + GYT+QKADKK+MEWFTV+EHY RT + EL+IGN YYFRVFS+NM G S
Sbjct: 955 PKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLS 1014
Query: 1149 DRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSP 1208
+ A TKE I R G Y+ P Y+ DFSEAP FTQPLVN IAGY A L C+VRG+P
Sbjct: 1015 EDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNP 1074
Query: 1209 KPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRL 1268
KPKI+W KN + + +D R+RMFS QGV TLEIRKP P+DGG Y C+A N G EC+L
Sbjct: 1075 KPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKL 1134
Query: 1269 EVRV 1272
EV+V
Sbjct: 1135 EVKV 1138
Score = 39.3 bits (90), Expect = 0.024
Identities = 33/131 (25%), Positives = 51/131 (38%), Gaps = 6/131 (4%)
Query: 6 KKPVSAFSK-KPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRH 64
+K +AF+K + +V G F E ++V+W + G +I S KY +G +
Sbjct: 248 EKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQR 307
Query: 65 TLTVREVGPADQGSYAVIAGSSKVKFDLKVIEAEKAEPMLAPAPAPAEATGAPGEAPAPA 124
L + D Y V AG K +L V EP + + T GE
Sbjct: 308 ILFINNCQMTDDSEYYVTAGDEKCSTELFV-----REPPIMVTKQLEDTTAYCGERVELE 362
Query: 125 AELGESAPSPK 135
E+ E + K
Sbjct: 363 CEVSEDDANVK 373
Score = 39.3 bits (90), Expect = 0.024
Identities = 23/97 (23%), Positives = 41/97 (42%), Gaps = 6/97 (6%)
Query: 6 KKPVSAFSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDI--SASNKYGLATEGTR 63
++P +K+ G E E V+W + G +I ++Y + EG +
Sbjct: 338 REPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKK 397
Query: 64 HTLTVREVGPADQGSYAVIA----GSSKVKFDLKVIE 96
H L + AD Y+V+ S+K+ DLK ++
Sbjct: 398 HILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLK 434
>gi|55956914 myosin binding protein H [Homo sapiens]
Length = 477
Score = 434 bits (1117), Expect = e-121
Identities = 211/424 (49%), Positives = 281/424 (66%), Gaps = 5/424 (1%)
Query: 848 AVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVE 907
A A ++P+P S+ PS P L ++DVS ++V++ W PPER+G GL GY +E
Sbjct: 54 APTASTATKPAPPSEDV-----PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLE 108
Query: 908 YCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEI 967
C EG SEWV T V++L G + L RV A + AG G P +P+ ++E
Sbjct: 109 LCREGASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIREN 168
Query: 968 LQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTD 1027
++ P++++PRHLRQT ++VGE VNL IPFQGKP+PQ TWT G L + VS+R D
Sbjct: 169 IEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQD 228
Query: 1028 TILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWK 1087
+ILFIR+A+R SG Y++TVR+E++E KA + + V++KP PP +R+ D WG N AL+W
Sbjct: 229 SILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWT 288
Query: 1088 PPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGF 1147
PPQD GNTEL GY VQKADKKT +WFTVLE Y T C + +LIIGN Y FRVFS+N+ G
Sbjct: 289 PPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGL 348
Query: 1148 SDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGS 1207
S A TKE I + I +P + DFSEAPSFTQPL + + GY+ L C+VR S
Sbjct: 349 STSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRAS 408
Query: 1208 PKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECR 1267
PKPKI W KN +++ + ++R S+QGV TLEIRKP PFD G+Y C+A N+ GEA +CR
Sbjct: 409 PKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCR 468
Query: 1268 LEVR 1271
LEV+
Sbjct: 469 LEVK 472
Score = 69.7 bits (169), Expect = 2e-11
Identities = 51/213 (23%), Positives = 88/213 (41%), Gaps = 33/213 (15%)
Query: 643 EPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAP 702
E PKI + P + T + G + L +P G P P W + A +
Sbjct: 170 EAPKIRV--PRHLRQTYIRQVGETVNLQIPFQGKPKPQATWT------HNGHALDSQRVS 221
Query: 703 EDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQV 762
TGD D SI + A++ D G Y +TV+ E +
Sbjct: 222 MRTGDQD------------------------SILFIRSAQRSDSGRYELTVRVEDLEAKA 257
Query: 763 NLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLN 822
+ + VI+ P P++ ++ +V + +QW PP G +LGY++++ KK+ +W +
Sbjct: 258 VIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTV- 316
Query: 823 FDLIQELSHEARRMIEGVVYEMRVYAVNAIGMS 855
+ + +I G Y RV++ N G+S
Sbjct: 317 LERYHPTTCTISDLIIGNSYSFRVFSENLCGLS 349
Score = 56.2 bits (134), Expect = 2e-07
Identities = 43/164 (26%), Positives = 68/164 (41%), Gaps = 15/164 (9%)
Query: 701 APEDTGDSDEWVFDKKLLCETEGRVRV-ETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGE 759
+PE+T K E G V V E+T++ + + + T T P E
Sbjct: 13 SPEETASESA----KVPTAEPPGEVAVSESTREEQVPKPQAPAPQAPTASTATKPAPPSE 68
Query: 760 DQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWM 819
D VP AP + +V S TV WEPP G + GY+LE ++ + W+
Sbjct: 69 D----------VPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWV 118
Query: 820 RLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQP 863
++ + R + G + +RV AV++ G P+ QP
Sbjct: 119 PVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQP 162
>gi|194018539 myosin binding protein H-like [Homo sapiens]
Length = 354
Score = 344 bits (882), Expect = 4e-94
Identities = 162/324 (50%), Positives = 214/324 (66%)
Query: 950 AGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTK 1009
A PG + P + I + P++ LPR LRQT +KVG+ VNLLIPFQGKP+PQ WT
Sbjct: 30 ASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTH 89
Query: 1010 EGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPP 1069
+G L VS+RN D+ILFIR A+R SG YQ+ V++ +E AT+ + V+++P PP
Sbjct: 90 DGCALDTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPP 149
Query: 1070 QDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPEL 1129
Q +++ D WG + LEW PPQD GNT L GYTVQKAD K+ WFTVLEHY RT C+V +L
Sbjct: 150 QSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDL 209
Query: 1130 IIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVN 1189
IIGN Y FRVF++N G S+ A T + I + Y+ + DFSEAP FTQPL +
Sbjct: 210 IIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFTQPLAD 269
Query: 1190 RSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGG 1249
+ + GY L C VR SP+PKI W KN +D+ + ++R + G+ +LEIRKP PFDGG
Sbjct: 270 CTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGG 329
Query: 1250 IYVCRATNLQGEARCECRLEVRVP 1273
IY C+A N GEA +CR++V+VP
Sbjct: 330 IYTCKAVNPLGEASVDCRVDVKVP 353
Score = 73.2 bits (178), Expect = 2e-12
Identities = 66/260 (25%), Positives = 103/260 (39%), Gaps = 41/260 (15%)
Query: 600 KLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTI 659
KL + + +PAD P A + + +L P +E PKI L P + T
Sbjct: 14 KLKVKEASPADAEPPQASPGQGAGSPTPQL--------LPPIEEHPKIWL--PRALRQTY 63
Query: 660 VVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLC 719
+ G+ + L +P G P P IW D D +
Sbjct: 64 IRKVGDTVNLLIPFQGKPKPQAIWTH-----------------------DGCALDTR--- 97
Query: 720 ETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPK 779
RV V + SI + A++ D G Y + V+ E + + VI+ P P + K
Sbjct: 98 ----RVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIK 153
Query: 780 ISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEG 839
+ +V S T++W PP G +LGY +++ KS W + + S +I G
Sbjct: 154 LVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV-LEHYHRTSCIVSDLIIG 212
Query: 840 VVYEMRVYAVNAIGMSRPSP 859
Y RV+A N G+S +P
Sbjct: 213 NSYAFRVFAENQCGLSETAP 232
Score = 56.2 bits (134), Expect = 2e-07
Identities = 45/172 (26%), Positives = 68/172 (39%), Gaps = 19/172 (11%)
Query: 860 ASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAA 919
A+ + I P P + + DV + +L+W PP+ G L GY+V+ W
Sbjct: 136 ATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV 195
Query: 920 LQGLTEHTSILVKDLPTGARLLFRVRAHNMAG--PGAPVTT-------------TEPVTV 964
L+ TS +V DL G FRV A N G AP+TT T+
Sbjct: 196 LEHY-HRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQ 254
Query: 965 QEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAG 1016
++ + P+ P T+ G L + PRP++ W K + G
Sbjct: 255 RDFSEAPKFTQPLADCTTV---TGYNTQLFCCVRASPRPKIIWLKNKMDIQG 303
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 286 bits (732), Expect = 9e-77
Identities = 238/845 (28%), Positives = 366/845 (43%), Gaps = 77/845 (9%)
Query: 386 ELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCST 445
+L+ A VKW +NG+EI+ G KY FE G+ L I C L D+ Y C V K
Sbjct: 12845 QLSREKANVKWYRNGREIK-EGKKYKFEKDGSIHRLIIKDCRLDDECEYACGVEDRKSRA 12903
Query: 446 ELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKK 505
LFV+E PV I RP +D L G V F E++++ +V+WL++ + + + + K++
Sbjct: 12904 RLFVEEIPVEIIRPPQDILEAPGADVVFLAELNKDKVEVQWLRNNMVVVQGD--KHQMMS 12961
Query: 506 DGQRHHLIINEAMLEDAGHYALCTSGGQALAEL-IVQEKKLEVYQSIADLMVGAKDQAVF 564
+G+ H L I + D G Y +A A+L + K++ + VG V
Sbjct: 12962 EGKIHRLQICDIKPRDQGEYRFIAKDKEARAKLELAAAPKIKTADQDLVVDVGKPLTMVV 13021
Query: 565 KCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACN 624
+ + W K + L S + I + D+ Y V + N
Sbjct: 13022 PYDAYPK-AEAEWFKENEPL---STKTIDTTAEQTSFRILEAKKGDKGRYKIVLQ----N 13073
Query: 625 LSAKLH-FMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIW 683
K F+ +K+ +D PG + + L+V + D ++ W
Sbjct: 13074 KHGKAEGFINLKV------------IDVPGPVRN-----------LEVTETFDGEVSLAW 13110
Query: 684 QKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEK 743
++ +T G + + + D+ CE FTV G +K
Sbjct: 13111 EEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAESCE---------------FTVTGLQK 13155
Query: 744 ED-EGVYTVTVKNPVGEDQVNLTVKVI------DVPDAPAAPKISNVGEDSCTVQWEPPA 796
E ++ V+ +N VG + T + DVP P I++V ++ WEPP
Sbjct: 13156 GGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRFGVSLTWEPPE 13215
Query: 797 YDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSR 856
YDGG I Y++E + K S RW ++LS ++EG Y RV A N IG+ +
Sbjct: 13216 YDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGK 13275
Query: 857 PSPASQPFM----PIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEG 912
PS A+ PF+ PI PS P +L D + ++V LKW PP + G + GY +E C EG
Sbjct: 13276 PSAAT-PFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEG 13334
Query: 913 CSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPR 972
W+ L + V L G + L+RV A N AG P P+T + P
Sbjct: 13335 KDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPT 13394
Query: 973 LQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPL-AGEEVSIRNSPTDTILF 1031
+ L + ++ V P+ +L+P G PRP TW + L G+ V ++ L
Sbjct: 13395 MDLSA-FKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELV 13453
Query: 1032 IRAARRVHSGTYQVTVRIENMED--KATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPP 1089
I + R G Y T+++EN + + V+ +PS P++L+ D +V L W+PP
Sbjct: 13454 ISPSERSDKGIY--TLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHLTWEPP 13511
Query: 1090 QDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSD 1149
D G + L GY V+K + W V++ VP+L+ G Y F+V ++N G
Sbjct: 13512 DDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCG-PG 13570
Query: 1150 RAATTKEPVFIPRPGITYEPP-NYKALDFSEAPSFT--QPLVN--RSVIAGYTAMLCCAV 1204
A EPV + P +PP N K D + F P N S I GY C
Sbjct: 13571 EPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERC--P 13628
Query: 1205 RGSPK 1209
RGS K
Sbjct: 13629 RGSDK 13633
Score = 243 bits (619), Expect = 1e-63
Identities = 204/708 (28%), Positives = 303/708 (42%), Gaps = 81/708 (11%)
Query: 567 EVSDENVRGVWLKNGKELVPDSRIKVSHI--GRVHKLTIDDVTPADEADYSFVPEGFACN 624
+V DE R + E P+++ KV+ + G+ +K + V A E+D + VPE
Sbjct: 17153 KVGDEEWRRA--NHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVK 17210
Query: 625 LSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQ 684
R EPP++ LD I V G+ LRL I G P P V W+
Sbjct: 17211 ---------------DRLEPPELILDANMAREQHIKV--GDTLRLSAIIKGVPFPKVTWK 17253
Query: 685 KAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKE 744
K DAP + R++ T S + A E
Sbjct: 17254 KEDR-----------DAPT--------------------KARIDVTPVGSKLEIRNAAHE 17282
Query: 745 DEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPIL 804
D G+Y++TV+NP G V++ V V+D P P ++S + +DSC + W+ P DGG I
Sbjct: 17283 DGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVIT 17342
Query: 805 GYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMS------RPS 858
Y++ER+ S +W L+ ++ SH A+ + EG Y RV A N G +P
Sbjct: 17343 NYVVERRDVASAQWSPLS-ATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPI 17401
Query: 859 PASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVA 918
A P P GPP + H+ DV T VSL W P+R G + GY VEY EG +W+
Sbjct: 17402 KALDPLHPPGPPKDLHHV---DVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIK 17458
Query: 919 ALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRH 978
+ +V L G FRV+A N+ G G P TT P+ QE L P ++L
Sbjct: 17459 F--KTVTNLECVVTGLQQGKTYRFRVKAENIVGLGLP-DTTIPIECQEKLVPPSVELDVK 17515
Query: 979 LRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPL-AGEEVSIRNSPTDTILFIRAARR 1037
L + + K G V +G P P WT +G + E ++ ++L I+ R
Sbjct: 17516 LIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLR 17575
Query: 1038 VHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQ-DLRVTDAWGLNVALEWKPPQDVGNTE 1096
+G YQ+TV + L V+D P PP + + D ++ + W+PP+D G +
Sbjct: 17576 RDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTISWQPPKDDGGSP 17635
Query: 1097 LWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFS---DRAAT 1153
+ Y V+K D + W V +T +P L G Y FRV ++N +G D T
Sbjct: 17636 VINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPT 17695
Query: 1154 TKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVN-RSVIAGY------TAMLCCAVRG 1206
+ F P P +P + + S+T P + S I GY V
Sbjct: 17696 VAKHKFSP-PSPPGKPVVTDITENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVNK 17754
Query: 1207 SPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCR 1254
+P + + GL G FR+F++ + KP P I CR
Sbjct: 17755 TPIADLKFRVTGLYEGNTYEFRVFAEN---LAGLSKPSPSSDPIKACR 17799
Score = 238 bits (608), Expect = 2e-62
Identities = 190/681 (27%), Positives = 288/681 (42%), Gaps = 96/681 (14%)
Query: 344 DLRGMLKRLKGMRRDEKKSTAFQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEI 403
DLR +++ LK + EKKS F K+ RL V L KW KNG+E+
Sbjct: 12733 DLR-IVEPLKDIETMEKKSVTFWCKVN-----------RLNVTL-------KWTKNGEEV 12773
Query: 404 QMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCSTELFVKEPPVLITRPLEDQ 463
++ + K LTI C D+ Y G +K EL + E P LEDQ
Sbjct: 12774 PFD-NRVSYRVDKYKHMLTIKDCGFPDEGEYIVTAGQDKSVAELLIIEAPTEFVEHLEDQ 12832
Query: 464 LVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAG 523
V F C++S E A VKW ++G E+ +E KY+F+KDG H LII + L+D
Sbjct: 12833 TVTEFDDAVFSCQLSREKANVKWYRNGREI--KEGKKYKFEKDGSIHRLIIKDCRLDDEC 12890
Query: 524 HYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKE 583
YA ++ A L V+E +E+ + D++ VF E++ + V WL+N
Sbjct: 12891 EYACGVEDRKSRARLFVEEIPVEIIRPPQDILEAPGADVVFLAELNKDKVEVQWLRNNMV 12950
Query: 584 LVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQE 643
+V + ++ G++H+L I D+ P D+ +Y F+ AK K++
Sbjct: 12951 VVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFI---------AKDKEARAKLELA---A 12998
Query: 644 PPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPE 703
PKI +VV G L + VP P W K
Sbjct: 12999 APKIK-----TADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKE----------------- 13036
Query: 704 DTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVN 763
++ L +T ++TT +++ F + A+K D+G Y + ++N G+ +
Sbjct: 13037 ----------NEPLSTKT-----IDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGF 13081
Query: 764 LTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNF 823
+ +KVIDVP +++ + ++ WE P DGG I+GY++ER+ K W+ L
Sbjct: 13082 INLKVIDVPGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWV-LAT 13140
Query: 824 DLIQELSHEARRMIE-GVVYEMRVYAVNAIGMSRPSPASQPF---MPIGPPSEPTHLAVE 879
D + + + GV Y RV A N +G P P P P ++ +
Sbjct: 13141 DRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTIT 13200
Query: 880 DVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGAR 939
DV+ VSL W PPE G + Y +E + W A+ E S V D+ G
Sbjct: 13201 DVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQE 13260
Query: 940 LLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQG 999
FRVRA N G G P T V V + ++RP PVNL Q
Sbjct: 13261 YSFRVRAQNRIGVGKPSAATPFVKVADPIERP----------------SPPVNLTSSDQT 13304
Query: 1000 KPRPQVTWTKE----GQPLAG 1016
+ Q+ W G P+ G
Sbjct: 13305 QSSVQLKWEPPLKDGGSPILG 13325
Score = 236 bits (601), Expect = 1e-61
Identities = 159/530 (30%), Positives = 248/530 (46%), Gaps = 48/530 (9%)
Query: 641 RQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPD 700
R EPP+I LD R +V+ A LRL V I G P P V W+KA
Sbjct: 25101 RIEPPEIELDADLR--KVVVLRASATLRLFVTIKGRPEPEVKWEKA-------------- 25144
Query: 701 APEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGED 760
+ +L + R ++E T ++ ++ + D G Y +T++N G
Sbjct: 25145 --------------EGILTD---RAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSGSK 25187
Query: 761 QVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKK--KKSYRW 818
+ V+V+D P AP I V +DS T+ WEPP DGG I YI+E+++ +K+Y
Sbjct: 25188 TAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYAT 25247
Query: 819 MRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAV 878
+ N + + + EG Y RV A N G+ P+ ++P PP P + +
Sbjct: 25248 ITNN---CTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTL 25304
Query: 879 EDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGA 938
DV+ T ++KW PE G + GY VE +G +W Q T +I L G
Sbjct: 25305 VDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVKTLEATI--SGLTAGE 25362
Query: 939 RLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQ 998
+FRV A N G P PV ++I +P ++LP H T K E + + +PF+
Sbjct: 25363 EYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFH---TFNVKAREQLKIDVPFK 25419
Query: 999 GKPRPQVTWTKEGQPLAGE-EVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKAT 1057
G+P+ V W K+GQ L V++ +S T T L I+ A + GTY++ V
Sbjct: 25420 GRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVP 25479
Query: 1058 LVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLE 1117
+ + V+D+P PP +R+ + ++ + W PP+ G ++ Y V+K + + W V +
Sbjct: 25480 ITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQ 25539
Query: 1118 HYRRTHCVVPELIIGNGYYFRVFSQNMVG---FSDRAATTKEPVFIPRPG 1164
RT + L G+ Y FRV ++N G +S+ +A E F P PG
Sbjct: 25540 AVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSP-PG 25588
Score = 234 bits (596), Expect = 5e-61
Identities = 179/608 (29%), Positives = 272/608 (44%), Gaps = 59/608 (9%)
Query: 577 WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKI 636
W G +L R+ V +V KLTI + T D +Y+ + S +K+
Sbjct: 29772 WFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSET-----IKV 29826
Query: 637 DFVPRQEPPK--IHLDCPGRIPDTIVVVAGNKLRLD--VPISGDPAPTVIWQKAITQGNK 692
+ + PP I +D I T + ++ LD P+SG V+ Q+
Sbjct: 29827 IILDKPGPPTGPIKID---EIDATSITISWEPPELDGGAPLSG----YVVEQR------- 29872
Query: 693 APARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVT 752
DA G + V + RS F + +E V+ V
Sbjct: 29873 -------DA------------------HRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVA 29907
Query: 753 VKNPVG-----EDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYI 807
N G + +V I +P P +I +V D T+ W PP DGG + GYI
Sbjct: 29908 ATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYI 29967
Query: 808 LERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM-- 865
+ERK+ ++ RW+R+N + + + + EG+ YE RV A+NA G +PS S+P +
Sbjct: 29968 VERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAM 30027
Query: 866 -PIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLT 924
PI PP +P + V D + T+VSL W PE G + GY +E EW T
Sbjct: 30028 DPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPT 30087
Query: 925 EHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQ 984
+ + LP GA FRV A N GPG P V V E+L+ P +L ++ I
Sbjct: 30088 KIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGIF 30147
Query: 985 KKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQ 1044
+ G + L IP +GKP P WTKEGQ ++ + I S T T L I+ A R SGTY
Sbjct: 30148 VRQGGVIRLTIPIKGKPFPICKWTKEGQDIS-KRAMIATSETHTELVIKEADRGDSGTYD 30206
Query: 1045 VTVRIENMEDKATLVLQVVDKPSPPQ-DLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQ 1103
+ + + + + ++V+ P+ P+ L D +V + W+PP D G ++ GY ++
Sbjct: 30207 LVLENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILE 30266
Query: 1104 KADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRP 1163
+ + W+T+ R T VV L Y+FRV ++N G S + ++EPV P
Sbjct: 30267 RREVPKAAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAENQFGIS-KPLKSEEPVTPKTP 30325
Query: 1164 GITYEPPN 1171
EPP+
Sbjct: 30326 LNPPEPPS 30333
Score = 232 bits (591), Expect = 2e-60
Identities = 155/508 (30%), Positives = 236/508 (46%), Gaps = 43/508 (8%)
Query: 702 PEDTGDSD--EWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVG- 758
P+D G S +V +K+ + V V + +T+ + E V+ + +N G
Sbjct: 16241 PKDDGGSKITNYVIEKRE-ANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGI 16299
Query: 759 ----EDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKK 814
+ + + VP AP P +S+V +S TV WE P YDGG P+ GY LE K
Sbjct: 16300 GEPLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTT 16359
Query: 815 SYRWMRLNFDLIQEL----SHEARRMIEGVVYEMRVYAVNAIGM------SRPSPASQPF 864
S RW R+N D I+ + S++ +IEG Y+ RVYA+NA G+ S P+ A P
Sbjct: 16360 SKRWKRVNRDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPI 16419
Query: 865 MPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLT 924
P GPP V D + ++ L+W PP + G + GY VEY EG EW
Sbjct: 16420 APPGPPFPK----VTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEV 16475
Query: 925 EHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQ 984
T ++V L GA FRVRA N+AG G P T+ + +++ L P LQL +R I
Sbjct: 16476 RGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRDRIV 16535
Query: 985 KKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQ 1044
G + ++ GKP P VTW + L +E +I + + + I+ +R H G Y
Sbjct: 16536 VHAGGVIRIIAYVSGKPPPTVTWNMNERTLP-QEATIETTAISSSMVIKNCQRSHQGVYS 16594
Query: 1045 VTVRIENMEDKATLVLQVVDKPSP-PQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQ 1103
+ + E E K T+++ V+D P P + + L W P+D G + + Y ++
Sbjct: 16595 LLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIE 16654
Query: 1104 KADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGF-----SDRAATTKEPV 1158
K + W V R + V LI G Y+FR+ ++N +G + A +EP+
Sbjct: 16655 KRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPI 16714
Query: 1159 FIP-RP-------------GITYEPPNY 1172
+P RP +T+ PP Y
Sbjct: 16715 TVPERPEDLEVKEVTKNTVTLTWNPPKY 16742
Score = 232 bits (591), Expect = 2e-60
Identities = 161/590 (27%), Positives = 263/590 (44%), Gaps = 48/590 (8%)
Query: 643 EPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAP 702
E P++ LD + IVV AG R+ +P G P P + W +
Sbjct: 24020 EAPELDLD--SELRKGIVVRAGGSARIHIPFKGRPTPEITWSR----------------- 24060
Query: 703 EDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQV 762
+E F K V++E + + +++ ++ D G Y + ++N G
Sbjct: 24061 ------EEGEFTDK--------VQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSA 24106
Query: 763 NLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLN 822
+TVKV+D P P + V +DS + WEPP DGG + Y++++++ + ++
Sbjct: 24107 FVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRESTRKAYANVS 24166
Query: 823 FDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVS 882
+ S + + EG +Y RV A N G+ P PPS P + + DVS
Sbjct: 24167 -SKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEPPSPPGKVTLTDVS 24225
Query: 883 DTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLF 942
T+ SL W PE G + GY VE P+G +W ++ ++ + +V L +G F
Sbjct: 24226 QTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKW--SIVAESKVCNAVVTGLSSGQEYQF 24283
Query: 943 RVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPR 1002
RV+A+N G P PV +++ +P L+LP + T + GE + + IP G+PR
Sbjct: 24284 RVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFN---TYSIQAGEDLKIEIPVIGRPR 24340
Query: 1003 PQVTWTKEGQPL-AGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQ 1061
P ++W K+G+PL V++ + T T+L I+ + G Y VT L +
Sbjct: 24341 PNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVI 24400
Query: 1062 VVDKPSPP-QDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYR 1120
V++KP PP +R + V + W+PP G ++ Y V+K D T W V
Sbjct: 24401 VLEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATVA 24460
Query: 1121 RTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEA 1180
RT + +L G Y FR+F++N G S A + V + P ++ P F +
Sbjct: 24461 RTTIKITKLKTGTEYQFRIFAENRYGKS--APLDSKAVIVQYP---FKEPGPPGTPFVTS 24515
Query: 1181 PSFTQPLV--NRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFR 1228
S Q LV + V G T ++ + K I W K +D +F+
Sbjct: 24516 ISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFK 24565
Score = 231 bits (588), Expect = 4e-60
Identities = 175/602 (29%), Positives = 273/602 (45%), Gaps = 99/602 (16%)
Query: 643 EPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIW------------------- 683
EPP++ +D R D IVV AG L+++ I+G P P + W
Sbjct: 25785 EPPRVMMDVKFR--DVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTD 25842
Query: 684 ----------------QKAITQGNKAPAR-----------PAPDA--------------- 701
Q +T N A R P P A
Sbjct: 25843 NHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSL 25902
Query: 702 ----PEDTG--DSDEWVFDKK-------LLCETEGRVRVETTKDRSIFTVEGAEKEDEGV 748
P++ G D D ++ +K+ +CE G +++ + K + K +E +
Sbjct: 25903 SWGRPQEDGGADIDYYIVEKRETSHLAWTICE--GELQMTSCKVTKLL------KGNEYI 25954
Query: 749 YTVTVKNP--VGEDQVNLTVKVID---VPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPI 803
+ VT N VGE ++ +K +D VP P + +I++V ++S T+ W P DGG I
Sbjct: 25955 FRVTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEI 26014
Query: 804 LGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQP 863
GYI+ER++K S RW+R+N + +L ++ + EG YE RVYA NA G+S PS S
Sbjct: 26015 SGYIIERREKNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPL 26074
Query: 864 FM---PIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAAL 920
P+ PS P+ + D TT+++ W P G + GY+VEY ++W ++
Sbjct: 26075 IRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSI 26134
Query: 921 QGL--TEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRH 978
Q L TE+T + L TGA +FRV++ N G P +++P +E + P +
Sbjct: 26135 QSLRGTEYT---ISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSE 26191
Query: 979 LRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRV 1038
+R+T+ K G + +PF+G+P P V W+K L + + + T L I A R
Sbjct: 26192 MRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLR-TRAYVDTTDSRTSLTIENANRN 26250
Query: 1039 HSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELW 1098
SG Y +T++ TLV++V+D P PP ++ V D + L W P++ G +
Sbjct: 26251 DSGKYTLTIQNVLSAASLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDVPENDGGAPVK 26310
Query: 1099 GYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPV 1158
Y ++K + W +V + R V L G YYFRV +N G A TKE V
Sbjct: 26311 NYHIEKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVG-IPAETKEGV 26369
Query: 1159 FI 1160
I
Sbjct: 26370 KI 26371
Score = 230 bits (587), Expect = 6e-60
Identities = 151/532 (28%), Positives = 240/532 (45%), Gaps = 42/532 (7%)
Query: 641 RQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPD 700
R+E P +D R T++V AG + VP G P P V+W K PD
Sbjct: 26180 REEEPLFDIDSEMR--KTLIVKAGASFTMTVPFRGRPVPNVLWSK-------------PD 26224
Query: 701 APEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGED 760
T R V+TT R+ T+E A + D G YT+T++N +
Sbjct: 26225 TDLRT------------------RAYVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAA 26266
Query: 761 QVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMR 820
+ L VKV+D P P + +V ++S + W+ P DGG P+ Y +E+++ W+
Sbjct: 26267 SLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDVPENDGGAPVKNYHIEKREASKKAWVS 26326
Query: 821 LNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVED 880
+ + LS++ + EG +Y RV N G+ P+ + PS P L V
Sbjct: 26327 VTNNC-NRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGVKITEKPSPPEKLGVTS 26385
Query: 881 VSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARL 940
+S +VSL W PE G + Y VE +G WV + + T +V L +
Sbjct: 26386 ISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQKNWVKC--AVAKSTHHVVSGLRENSEY 26443
Query: 941 LFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGK 1000
FRV A N AG P PV ++E L+ P + + T+ + G + + IP GK
Sbjct: 26444 FFRVFAENQAGLSDPRELLLPVLIKEQLEPPEIDMKNFPSHTVYVRAGSNLKVDIPISGK 26503
Query: 1001 PRPQVTWTKEGQPL-AGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLV 1059
P P+VT +++G PL A + + + + ++ + +G Y++T + KA +
Sbjct: 26504 PLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFIN 26563
Query: 1060 LQVVDKPSPPQ-DLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEH 1118
+ V+D+P PP + ++D +V L+W+PP+ G +++ Y + K + T W V
Sbjct: 26564 IVVLDRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSAT 26623
Query: 1119 YRRTHCVVPELIIGNGYYFRVFSQNMVGFSDR----AATTKEPVFIPRPGIT 1166
RT V +L G Y FR+ ++N G SD T K P P P T
Sbjct: 26624 VARTMMKVMKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPST 26675
Score = 229 bits (585), Expect = 1e-59
Identities = 167/615 (27%), Positives = 275/615 (44%), Gaps = 63/615 (10%)
Query: 565 KCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACN 624
+CE +N W++ +LVP+ KV+ + + +K + V+ ++A S P
Sbjct: 13330 RCEEGKDN----WIRCNMKLVPELTYKVTGLEKGNKY-LYRVSAENKAGVSD-PSEILGP 13383
Query: 625 LSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQ 684
L+A F+E +D D + V+ N + + VP +G P PT W
Sbjct: 13384 LTADDAFVEPTMDL--------------SAFKDGLEVIVPNPITILVPSTGYPRPTATW- 13428
Query: 685 KAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKE 744
F K+L ET RV+++T + + +E+
Sbjct: 13429 ---------------------------CFGDKVL-ETGDRVKMKTLSAYAELVISPSERS 13460
Query: 745 DEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPIL 804
D+G+YT+ ++N V + V VI P AP K ++ +DS + WEPP DGG P+
Sbjct: 13461 DKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLT 13520
Query: 805 GYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPF 864
GY++E+++ W ++ D + +L +++G Y +V A N G P+ +P
Sbjct: 13521 GYVVEKREVSRKTWTKV-MDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPV 13579
Query: 865 ---MPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQ 921
P P P ++ D + ++ L W PP+ G + GY VE CP G +WVA +
Sbjct: 13580 NMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGE 13639
Query: 922 GLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQ 981
+ E T + V L G +RV+A N G P TE + + + P + L L
Sbjct: 13640 PVAE-TKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLA 13698
Query: 982 TIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEE-VSIRNSPTDTILFIRAARRVHS 1040
+ K G + L GKP P++TWTK L ++ ++I N P + + I ++R +
Sbjct: 13699 GLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDT 13758
Query: 1041 GTYQVTVRIENMEDKATLVLQ--VVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELW 1098
GTY + N+ +AT V++ V+DKP PP +TD + L W PP+D G +++
Sbjct: 13759 GTY--IIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKIT 13816
Query: 1099 GYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSD----RAATT 1154
Y V++ + W + + T+ +LI Y FRV ++NM G + T
Sbjct: 13817 NYVVERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITA 13876
Query: 1155 KEPVFIPRPGITYEP 1169
K P P EP
Sbjct: 13877 KYQFDPPGPPTRLEP 13891
Score = 225 bits (574), Expect = 2e-58
Identities = 166/609 (27%), Positives = 271/609 (44%), Gaps = 60/609 (9%)
Query: 643 EPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAP 702
E P I LD R I + AG LRL VPI G P P V W K
Sbjct: 22938 EAPDIDLDLELR--KIINIRAGGSLRLFVPIKGRPTPEVKWGKV---------------- 22979
Query: 703 EDTGDSDEWVFDKKLLCETEGRVR----VETTKDRSIFTVEGAEKEDEGVYTVTVKNPVG 758
+G +R ++ T + ++ + D G YT+T++N G
Sbjct: 22980 -------------------DGEIRDAAIIDVTSSFTSLVLDNVNRYDSGKYTLTLENSSG 23020
Query: 759 EDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKK--KKSY 816
+TV+V+D P P K++ + +DS ++ WEPP DGG I YI+E+++ +KSY
Sbjct: 23021 TKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEKREATRKSY 23080
Query: 817 RWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHL 876
+ N + S + ++ EG Y RV A N G+ P+ + P P P +
Sbjct: 23081 AAVVTN---CHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPPGKI 23137
Query: 877 AVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPT 936
V+DV+ +VSL W PE G + Y VE + +W + + ++ +L
Sbjct: 23138 TVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECAR--VKSLQAVITNLTQ 23195
Query: 937 GARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIP 996
G LFRV A N G P + P+ ++++ P ++ P ++Q VG+ + + +P
Sbjct: 23196 GEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVK-PAFSSYSVQ--VGQDLKIEVP 23252
Query: 997 FQGKPRPQVTWTKEGQPL-AGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDK 1055
G+P+P +TWTK+G PL +++ +S T L I+ + G Y +TV +
Sbjct: 23253 ISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKT 23312
Query: 1056 ATLVLQVVDKPSPPQ-DLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFT 1114
A++ + +DKP PP+ ++ D ++ L W PP G ++ Y VQK D T W
Sbjct: 23313 ASIEIVTLDKPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDV 23372
Query: 1115 VLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKA 1174
V RT V +L G Y FR+F++N G S A +P+ P Y+ P
Sbjct: 23373 VSATVARTTLKVTKLKTGTEYQFRIFAENRYGQS--FALESDPIVAQYP---YKEPGPPG 23427
Query: 1175 LDFSEAPSFTQPLV--NRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSK 1232
F+ A S ++ + V G + ++ + + I W K + D +F+ +
Sbjct: 23428 TPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNL 23487
Query: 1233 QGVLTLEIR 1241
+ + E R
Sbjct: 23488 EEGIEYEFR 23496
Score = 224 bits (571), Expect = 4e-58
Identities = 156/532 (29%), Positives = 231/532 (43%), Gaps = 44/532 (8%)
Query: 622 ACNLSAKLHFME--VKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAP 679
A N+ + E +I+ V R E P + L + T+ + AG LRL V +SG P P
Sbjct: 29419 AVNVKGMSEYSESIAEIEPVERIEIPDLEL--ADDLKKTVTIRAGASLRLMVSVSGRPPP 29476
Query: 680 TVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVE 739
+ W K QG + R ++TT+ S+ V+
Sbjct: 29477 VITWSK---QG----------------------------IDLASRAIIDTTESYSLLIVD 29505
Query: 740 GAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDG 799
+ D G YT+ +N G+ + VKV D P + K+ V DS T+ WE P DG
Sbjct: 29506 KVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDG 29565
Query: 800 GQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSP 859
G P+ YI+E K++ + R + + + ++EG +Y RV N G+ P
Sbjct: 29566 GAPVNNYIVE-KREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCE 29624
Query: 860 ASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEW--- 916
S + P P L V DV+ +TV+L W P G L GY +E C G W
Sbjct: 29625 TSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKV 29684
Query: 917 VAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLP 976
V + EHT V L G + LFR+RA N G P T VTVQ++ P + L
Sbjct: 29685 VTLKPTVLEHT---VTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLS 29741
Query: 977 RHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPL-AGEEVSIRNSPTDTILFIRAA 1035
++TI G PV L+IP G+P P +W G L E V++ L IR
Sbjct: 29742 TMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRET 29801
Query: 1036 RRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQ-DLRVTDAWGLNVALEWKPPQDVGN 1094
+G Y + ++ T+ + ++DKP PP +++ + ++ + W+PP+ G
Sbjct: 29802 TIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEPPELDGG 29861
Query: 1095 TELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVG 1146
L GY V++ D W V E R+ L GN Y FRV + N G
Sbjct: 29862 APLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFG 29913
Score = 220 bits (561), Expect = 6e-57
Identities = 171/617 (27%), Positives = 257/617 (41%), Gaps = 63/617 (10%)
Query: 575 GVWLKNGKELVPDSRIKVSHI--GRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFM 632
G W K E +R V+ + G +K + + A + D +C ++
Sbjct: 28298 GDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGD--------SCEVTGT---- 28345
Query: 633 EVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNK 692
I V R P++ +D T VV AG +RL + G P PT +W K
Sbjct: 28346 ---IKAVDRLTAPELDIDA--NFKQTHVVRAGASIRLFIAYQGRPTPTAVWSK------- 28393
Query: 693 APARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVT 752
PD+ R + TT S TVE + D G YT+T
Sbjct: 28394 ------PDS------------------NLSLRADIHTTDSFSTLTVENCNRNDAGKYTLT 28429
Query: 753 VKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKK 812
V+N G + TVKV+D P P +V S T+ W+ P DGG I Y++E+++
Sbjct: 28430 VENNSGSKSITFTVKVLDTPGPPGPITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKRE 28489
Query: 813 KKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSE 872
W ++ +++ + + EGV Y RV AVN G+ P +P + P+
Sbjct: 28490 ASRRSWQVISEKCTRQI-FKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAP 28548
Query: 873 PTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVK 932
P L V D S ++ L W P+ G + GY +E +G WV A G T+ + V+
Sbjct: 28549 PRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEA--GHTKQLTFTVE 28606
Query: 933 DLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVN 992
L FRV+A N AG P V ++E P L Q I K G P
Sbjct: 28607 RLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFT 28666
Query: 993 LLIPFQGKPRPQVTWTKEGQPL-AGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIEN 1051
+ +P G+P P+VTW E L + VSI + T L ++ + R SG Y +T+
Sbjct: 28667 IDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTA 28726
Query: 1052 MEDKATLVLQVVDKPSP-PQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTM 1110
++ + V+ +P P + V+ + L W P+D G TE+ Y V+K + T
Sbjct: 28727 GVKTFSVTVVVIGRPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTT 28786
Query: 1111 EWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFS---DRAATTKEPVFIP-----R 1162
W V +RT V L Y FRV S+N G S + A E F+P R
Sbjct: 28787 AWQLVNSSVKRTQIKVTHLTKYMEYSFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPTR 28846
Query: 1163 PGITYEPPNYKALDFSE 1179
P + + N ++ + E
Sbjct: 28847 PEVYHVSANAMSIRWEE 28863
Score = 219 bits (559), Expect = 1e-56
Identities = 172/604 (28%), Positives = 278/604 (46%), Gaps = 64/604 (10%)
Query: 577 WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKI 636
W+K +EL +R+++ L++ D D +Y + A S ++ VK+
Sbjct: 22577 WIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVN---VKV 22633
Query: 637 DFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPAR 696
LD PG P+ VV++G ++ + T+ W+ + G
Sbjct: 22634 ------------LDRPGP-PEGPVVISG--------VTAEKC-TLAWKPPLQDGGS---- 22667
Query: 697 PAPDAPEDTGDSDEWVFDKK---LLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTV 753
D ++ +++ L T V+T + +EG +E + +
Sbjct: 22668 ----------DIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEG----NEYTFRIMA 22713
Query: 754 KNPVG-----EDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYIL 808
N G E + + VPDAP AP+++ V +DS V WE PA DGG ILGY+L
Sbjct: 22714 VNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPASDGGSEILGYVL 22773
Query: 809 ERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPAS---QPFM 865
E++ K+ RW R + LI EL +IE YE RV A NA G+S PSP S +
Sbjct: 22774 EKRDKEGIRWTRCHKRLIGELRLRVTGLIENHDYEFRVSAENAAGLSEPSPPSAYQKACD 22833
Query: 866 PIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAAL--QGL 923
PI P P + V D++ ++V L W P G + GY VE C EW G+
Sbjct: 22834 PIYKPGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGI 22893
Query: 924 TEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTI 983
+ T+I V+ L FR+ A N AG G P+ V+E L+ P + L LR+ I
Sbjct: 22894 NK-TNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDLELRKII 22952
Query: 984 QKKVGEPVNLLIPFQGKPRPQVTWTK-EGQPLAGEEVSIRNSPTDTILFIRAARRVHSGT 1042
+ G + L +P +G+P P+V W K +G+ + + +S T +L R SG
Sbjct: 22953 NIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLVL--DNVNRYDSGK 23010
Query: 1043 YQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTV 1102
Y +T+ + A + ++V+D PSPP +L+VT+ +V++ W+PP G +++ Y V
Sbjct: 23011 YTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIV 23070
Query: 1103 QKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPV---F 1159
+K + + V+ + + + +L G YYFRV ++N G A T +P+
Sbjct: 23071 EKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIG-LPAQTADPIKVAE 23129
Query: 1160 IPRP 1163
+P+P
Sbjct: 23130 VPQP 23133
Score = 219 bits (557), Expect = 2e-56
Identities = 152/493 (30%), Positives = 234/493 (47%), Gaps = 38/493 (7%)
Query: 700 DAPEDTGDSD--EWVFDKKLLCETEGRVRVETTKDRSIFT----VEGAEKEDEGVYTVTV 753
D PED G + ++ +K CET+ V +T ++ T V + +E ++ V
Sbjct: 18318 DPPEDDGGCEIQNYILEK---CETKRMVW--STYSATVLTPGTTVTRLIEGNEYIFRVRA 18372
Query: 754 KNPVGEDQVNLTVKVI-----DVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYIL 808
+N +G + VI D P P P+++ V ++ TV W PP YDGG+ I GY L
Sbjct: 18373 ENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFL 18432
Query: 809 ERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM--- 865
E+K+K S RW+ +N I E + + ++ Y+ RV A N IG+ PS S+P +
Sbjct: 18433 EKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKD 18492
Query: 866 PIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCP--------EGCSEWV 917
PI PP PT+ V D + +++L W P G + GY VE P EG
Sbjct: 18493 PIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCN 18552
Query: 918 AALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPR 977
AA Q + + V L FRV A N G G P E + +EIL+ P + L
Sbjct: 18553 AAAQLVRK--EFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEPPEIDLDA 18610
Query: 978 HLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARR 1037
+R+ + + G P+ L +G+P P+VTW K G + + T L I + R
Sbjct: 18611 SMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDTMAFLVIPNSTR 18670
Query: 1038 VHSGTYQVTVRIENMEDKATLV-LQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTE 1096
SG Y +T+ + +KA V ++V+D P P DL+V+D + + W PP++ G ++
Sbjct: 18671 DDSGKYSLTL-VNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQ 18729
Query: 1097 LWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKE 1156
+ Y V+K + W TV ++T V L+ GN YYFRV + N G
Sbjct: 18730 VTHYIVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYG-------PGV 18782
Query: 1157 PVFIPRPGITYEP 1169
P +P+P + +P
Sbjct: 18783 PTDVPKPVLASDP 18795
Score = 218 bits (554), Expect = 4e-56
Identities = 174/627 (27%), Positives = 269/627 (42%), Gaps = 72/627 (11%)
Query: 573 VRGV------WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLS 626
+RGV W +G E+ D V LTI + D +Y A + +
Sbjct: 17534 IRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKT 17593
Query: 627 AKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKA 686
+H LD PG I + LDV T+ WQ
Sbjct: 17594 VAVHLTV---------------LDVPGPPTGPINI-------LDVT---PEHMTISWQP- 17627
Query: 687 ITQGNKAPARPAPDAPEDTGDSD--EWVFDKK-LLCETEGRVRVETTKDRSIFTVEGAEK 743
P+D G S ++ +K+ +T G V ++K + + +K
Sbjct: 17628 ---------------PKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTK--LKIPHLQK 17670
Query: 744 EDEGVYTVTVKNPVG-----EDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYD 798
E V+ V +N +G + + P P P ++++ E++ TV W P D
Sbjct: 17671 GCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWTLPKSD 17730
Query: 799 GGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPS 858
GG PI GY +ER++ +W+R+N I +L + EG YE RV+A N G+S+PS
Sbjct: 17731 GGSPITGYYMERREVTG-KWVRVNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPS 17789
Query: 859 PASQPFM---PIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSE 915
P+S P PI PP P + ++D S T L W P G + GY VE G ++
Sbjct: 17790 PSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQ 17849
Query: 916 WVAALQG-LTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQ 974
W + L + V L G FR++A N+ G G P E V ++IL P ++
Sbjct: 17850 WNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVE 17909
Query: 975 LPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEE-VSIRNSPTDTILFIR 1033
L R I +VG+ + +L +G+P P +TWTKEG+ L E+ V + L I+
Sbjct: 17910 LDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIK 17969
Query: 1034 AARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVG 1093
A R G Y ++ + + + + ++ V+D+P P Q+L+VT+ N + W+ P D G
Sbjct: 17970 EAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKENCTISWENPLDNG 18029
Query: 1094 NTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAAT 1153
+E+ + V+ W V + + L+ N YYFRV ++N VG
Sbjct: 18030 GSEITNFIVEYRKPNQKGWSIVASDVTK-RLIKANLLANNEYYFRVCAENKVGVGP-TIE 18087
Query: 1154 TKEPVF----IPRPGITYEPPNYKALD 1176
TK P+ I RPG EP N D
Sbjct: 18088 TKTPILAINPIDRPG---EPENLHIAD 18111
Score = 218 bits (554), Expect = 4e-56
Identities = 153/548 (27%), Positives = 243/548 (44%), Gaps = 49/548 (8%)
Query: 633 EVKIDFVPRQ--EPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQG 690
E+K P++ EPP+I LD R ++V AG +RL + G PAP V W+K G
Sbjct: 18590 ELKEAIKPKEILEPPEIDLDASMR--KLVIVRAGCPIRLFAIVRGRPAPKVTWRKV---G 18644
Query: 691 NKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYT 750
R +V+ + + + ++D G Y+
Sbjct: 18645 IDNVVRKG---------------------------QVDLVDTMAFLVIPNSTRDDSGKYS 18677
Query: 751 VTVKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILER 810
+T+ NP GE V + V+V+D P + K+S+V + SC V W PP DGG + YI+E+
Sbjct: 18678 LTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEK 18737
Query: 811 KKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PI 867
++ W + + +++ S ++ G Y RV AVN G P+ +P + P+
Sbjct: 18738 READRKTWSTVTPE-VKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPL 18796
Query: 868 GPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEG--CSEWVAALQGLTE 925
P P L V +++ + +L W PP R G +DGY Y E W + +
Sbjct: 18797 SEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTE--YSVVK 18854
Query: 926 HTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQK 985
S++V L G + FRV A N G P +E L P++ +P + I
Sbjct: 18855 DLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMP----EQITI 18910
Query: 986 KVGEPVNLLIPFQGKPRPQVTWTK-EGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQ 1044
K G+ + + GKP P W K E + + +++ + + +IL I+ R SG Y
Sbjct: 18911 KAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYS 18970
Query: 1045 VTVRIENMEDKATLVLQVVDKPSPPQD-LRVTDAWGLNVALEWKPPQDVGNTELWGYTVQ 1103
+T + D + + V+D P PPQ ++D +L W P + G + + Y V+
Sbjct: 18971 LTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSLSWHIPLEDGGSNITNYIVE 19030
Query: 1104 KADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRP 1163
K D +W T L +T C V +LI G Y FRV ++N G S+ + K P
Sbjct: 19031 KCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPF- 19089
Query: 1164 GITYEPPN 1171
G+ EP N
Sbjct: 19090 GVPSEPKN 19097
Score = 217 bits (552), Expect = 7e-56
Identities = 151/520 (29%), Positives = 234/520 (45%), Gaps = 42/520 (8%)
Query: 636 IDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPA 695
I+ R P + LD R D IVV AG +R+ +SG P PTV W
Sbjct: 16513 IEMKDRLVSPDLQLDASVR--DRIVVHAGGVIRIIAYVSGKPPPTVTWNMN--------E 16562
Query: 696 RPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKN 755
R P +ETT S ++ ++ +GVY++ KN
Sbjct: 16563 RTLPQ-----------------------EATIETTAISSSMVIKNCQRSHQGVYSLLAKN 16599
Query: 756 PVGEDQVNLTVKVIDVPDAPAAPKIS-NVGEDSCTVQWEPPAYDGGQPILGYILERKKKK 814
GE + + V V+DVP P ++ N+ +SC + W P DGG PI Y++E+++
Sbjct: 16600 EAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESD 16659
Query: 815 SYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PIGPPS 871
W + + + ++ + + +I+G Y R+ A N+IGM S+ + PI P
Sbjct: 16660 RRAWTPVTYTVTRQ-NATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPE 16718
Query: 872 EPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILV 931
P L V++V+ TV+L W PP+ G + Y +E G ++ V
Sbjct: 16719 RPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTV 16778
Query: 932 KDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPV 991
K L G +RV A N+ G G P T+P+T ++ L P L L + TI +VGE
Sbjct: 16779 KGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHLDFRDKLTI--RVGEAF 16836
Query: 992 NLLIPFQGKPRPQVTWTK-EGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIE 1050
L + GKP+P+V+W K E L + I+ +P L A+R SG Y V V
Sbjct: 16837 ALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENS 16896
Query: 1051 NMEDKATLVLQVVDKPSPPQD-LRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKT 1109
K + VVD+P PP + + + + WKPP D G +++ Y ++K +
Sbjct: 16897 TGSRKGFCQVNVVDRPGPPVGPVSFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGK 16956
Query: 1110 MEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSD 1149
W V +T C V +L+ G Y FR+ ++N+ G SD
Sbjct: 16957 DVWMPVTSASAKTTCKVSKLLEGKDYIFRIHAENLYGISD 16996
Score = 214 bits (546), Expect = 3e-55
Identities = 169/608 (27%), Positives = 283/608 (46%), Gaps = 58/608 (9%)
Query: 643 EPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAP 702
E P+I LD R +++ AG +++ +P G P PTV W+K
Sbjct: 27267 EAPEIDLDVALRT--SVIAKAGEDVQVLIPFKGRPPPTVTWRK----------------- 27307
Query: 703 EDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQV 762
D+K L ++ R +E T S+ T+ + D G Y +T++N VGE +
Sbjct: 27308 -----------DEKNL-GSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKS 27355
Query: 763 N-LTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRL 821
+ ++VKV+D P A ++ +V + T+ W+PP DGG PI+ Y++E++ W +
Sbjct: 27356 STVSVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVV 27415
Query: 822 NFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDV 881
+ S + + E + RV A N IG+ P ++P P+ L+++D
Sbjct: 27416 SHKC-SSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDS 27474
Query: 882 SDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLL 941
+ T+V L W P+ G + Y VE +G W A G+++ I V L + L
Sbjct: 27475 TKTSVILSWTKPDFDGGSVITEYVVERKGKGEQTWSHA--GISKTCEIEVSQLKEQSVLE 27532
Query: 942 FRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKP 1001
FRV A N G PVT P+TV+E++ P + L + ++G V+L +P++GKP
Sbjct: 27533 FRVFAKNEKGLSDPVTIG-PITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKP 27591
Query: 1002 RPQVTWTKEGQPLAGEEVSIRNSPTDT--ILFIRAARRVHSGTYQVTVRIENMEDKATLV 1059
+P ++W K+G PL E +R S T+ L I+ A++ H G Y TV ++N + +
Sbjct: 27592 KPSISWLKDGLPLKESEF-VRFSKTENKITLSIKNAKKEHGGKY--TVILDNAVCRIAVP 27648
Query: 1060 LQVV--DKPSPPQ-DLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVL 1116
+ V+ PS P+ +R + +V L W P+D G E+ Y+++K + W V
Sbjct: 27649 ITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTNWKMVC 27708
Query: 1117 EHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATT----KEPVFIPRPGITYEPPNY 1172
RT VP L+ Y FRV ++N G S ++ K IP P +P Y
Sbjct: 27709 SSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGP--PGKPVIY 27766
Query: 1173 KALDFSEAPSFTQPLVN-RSVIAGY-------TAMLCCAVRGSPKPKISWFKNGLDLGED 1224
+ ++ P+ + S + G+ ++L V SP + GL G D
Sbjct: 27767 NVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLD 27826
Query: 1225 ARFRMFSK 1232
+FR++++
Sbjct: 27827 YQFRVYAE 27834
Score = 213 bits (543), Expect = 7e-55
Identities = 137/438 (31%), Positives = 210/438 (47%), Gaps = 12/438 (2%)
Query: 732 DRSIFTVEGAEKEDEGVYTVTVKNPVG-----EDQVNLTVKVIDVPDAPAAPKISNVGED 786
+ I T K +E ++ V N G E + P P P+++ + ++
Sbjct: 27021 EECIITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKN 27080
Query: 787 SCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRV 846
S TV W P DGG I GY LE++ KKS W ++ + I++ + + E Y+ RV
Sbjct: 27081 SMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRV 27140
Query: 847 YAVNAIGM---SRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDG 903
AVNA G S PS + PI PP P + + D + ++++L W P G + G
Sbjct: 27141 CAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTG 27200
Query: 904 YSVEYCPEGCSEWVA-ALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPV 962
Y VE EW + +G T +V +L G FRV A N AG G P+ EPV
Sbjct: 27201 YVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPV 27260
Query: 963 TVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGE-EVSI 1021
++IL+ P + L LR ++ K GE V +LIPF+G+P P VTW K+ + L + SI
Sbjct: 27261 QAKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSI 27320
Query: 1022 RNSPTDTILFIRAARRVHSGTYQVTVRIENMEDK-ATLVLQVVDKPSPPQDLRVTDAWGL 1080
N+ + ++L I R +G Y +T+ E K +T+ ++V+D P+ Q L+V
Sbjct: 27321 ENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRG 27380
Query: 1081 NVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVF 1140
V L W PP G + + Y ++K D W V T + +L ++FRV
Sbjct: 27381 TVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVL 27440
Query: 1141 SQNMVGFSDRAATTKEPV 1158
++N +G + TT EPV
Sbjct: 27441 AENEIGIGEPCETT-EPV 27457
Score = 212 bits (540), Expect = 2e-54
Identities = 170/605 (28%), Positives = 264/605 (43%), Gaps = 59/605 (9%)
Query: 641 RQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPD 700
R PP+I LD R + + A LRL VPI G PAP V W +
Sbjct: 21854 RMLPPEIELDADLR--KVVTIRACCTLRLFVPIKGRPAPEVKWAR--------------- 21896
Query: 701 APEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGED 760
D G+S + + +E+T ++ V + D G Y +TV+N G
Sbjct: 21897 ---DHGESLD-------------KASIESTSSYTLLIVGNVNRFDSGKYILTVENSSGSK 21940
Query: 761 QVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKK--KKSYRW 818
+ V+V+D P P K+ V + S T+ W+PP DGG I YI+E+++ +K+Y
Sbjct: 21941 SAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVEKRESTRKAYST 22000
Query: 819 MRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAV 878
+ N + S + ++ EG Y RV A N G+ P+ ++ P P + +
Sbjct: 22001 VATN---CHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKASERPLPPGKITL 22057
Query: 879 EDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGA 938
DV+ +VSL W PE G + GY VE +G +W A + T + L G
Sbjct: 22058 MDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKW--ATCATVKVTEATITGLIQGE 22115
Query: 939 RLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQ 998
FRV A N G P + PV ++++ P +L L T GE + + +PF
Sbjct: 22116 EYSFRVSAQNEKGISDPRQLSVPVIAKDLVIPPAFKL---LFNTFTVLAGEDLKVDVPFI 22172
Query: 999 GKPRPQVTWTKEGQPL-AGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKAT 1057
G+P P VTW K+ PL V+ ++ +++L I+ A R G Y V + E T
Sbjct: 22173 GRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIET 22232
Query: 1058 LVLQVVDKPSPPQ-DLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVL 1116
L + V+DKP PP +++ + ++ L W PP+ G + + Y V+K D T W V
Sbjct: 22233 LNVIVLDKPGPPTGPVKMDEVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTWQIVS 22292
Query: 1117 EHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALD 1176
RT L G Y FR+ ++N G S EP P PP +
Sbjct: 22293 ATVARTTIKACRLKTGCEYQFRIAAENRYGKS--TYLNSEPTVAQYPFKVPGPPGTPVVT 22350
Query: 1177 FSEAPS----FTQPLVN-RSVIAGY-------TAMLCCAVRGSPKPKISWFKNGLDLGED 1224
S S + +P+ + S + GY ++L + +P P+ + GL+ G +
Sbjct: 22351 LSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGVE 22410
Query: 1225 ARFRM 1229
FR+
Sbjct: 22411 YEFRV 22415
Score = 211 bits (537), Expect = 4e-54
Identities = 158/561 (28%), Positives = 244/561 (43%), Gaps = 48/561 (8%)
Query: 644 PPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPE 703
PP+ LD R T+++ AG +RL VP+ G P P + W K P + +
Sbjct: 19690 PPEGELDADLR--KTLILRAGVTMRLYVPVKGRPPPKITWSK-----------PNVNLRD 19736
Query: 704 DTG-DSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQV 762
G D FD L C E K D G Y +T++N G+ +
Sbjct: 19737 RIGLDIKSTDFDTFLRC-------------------ENVNKYDAGKYILTLENSCGKKEY 19777
Query: 763 NLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLN 822
+ VKV+D P P + + +DS V WEPP DGG PI+ Y+++++ + W +
Sbjct: 19778 TIVVKVLDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVT 19837
Query: 823 FDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVS 882
+ + S + EG Y RV+A N G+ P P L V VS
Sbjct: 19838 TE-CSKTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVVDLKVRSVS 19896
Query: 883 DTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLF 942
++ S+ W+ P G + GY V++ E ++W ++ L+ S KDL G F
Sbjct: 19897 KSSCSIGWKKPHSDGGSRIIGYVVDFLTEE-NKWQRVMKSLSLQYS--AKDLTEGKEYTF 19953
Query: 943 RVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPR 1002
RV A N G G P T V ++ + P L L K L IP +GKP
Sbjct: 19954 RVSAENENGEGTPSEIT--VVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPA 20011
Query: 1003 PQVTWTKEGQPLAGE-EVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQ 1061
P V+W K PLA + VS+ +S +T L + ++ +G Y +T++ + T+ ++
Sbjct: 20012 PSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIK 20071
Query: 1062 VVDKPS-PPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYR 1120
VV KP P ++ + + L+W PP+D G +E+ Y ++K D +W T +
Sbjct: 20072 VVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCASAVQ 20131
Query: 1121 RTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRP-GITYEPPNYKALDF-- 1177
+T V L G Y FRV ++N G + EP+ P + PP +D
Sbjct: 20132 KTTFRVTRLHEGMEYTFRVSAENKYGVGE--GLKSEPIVARHPFDVPDAPPPPNIVDVRH 20189
Query: 1178 -SEAPSFTQP-LVNRSVIAGY 1196
S + ++T P S I GY
Sbjct: 20190 DSVSLTWTDPKKTGGSPITGY 20210
Score = 211 bits (537), Expect = 4e-54
Identities = 149/517 (28%), Positives = 234/517 (45%), Gaps = 47/517 (9%)
Query: 636 IDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPA 695
++ V R+ P LD R T+VV AG +R+ VPI G PAP V W K
Sbjct: 20765 VEIVEREMAPDFELDAELR--RTLVVRAGLSIRIFVPIKGRPAPEVTWTK---------- 20812
Query: 696 RPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKN 755
D+ + R +E T+ ++ + + D G + +T++N
Sbjct: 20813 -----------DN----------INLKNRANIENTESFTLLIIPECNRYDTGKFVMTIEN 20851
Query: 756 PVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKK--K 813
P G+ + V+V+D P + +++ +DS T+ W+ P DGG I YI+E+++ +
Sbjct: 20852 PAGKKSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATR 20911
Query: 814 KSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEP 873
KSY + +++ + EG Y RV A N G+ P+ ++P PS P
Sbjct: 20912 KSYSTATTK---CHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPP 20968
Query: 874 THLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEW--VAALQGLTEHTSILV 931
L + D++ +TVSL W P+ G + GY +E +G +W + ++GL +V
Sbjct: 20969 DSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQWTHITTVKGL----ECVV 21024
Query: 932 KDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPV 991
++L G F+V A N AG AP + PV V+E P L L ++ + K G+ +
Sbjct: 21025 RNLTEGEEYTFQVMAVNSAGRSAP-RESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNI 21083
Query: 992 NLLIPFQGKPRPQVTWTKEGQPL-AGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIE 1050
+ IP G+P+P VTW K Q L + V+ + T TIL I R SG Y +T R
Sbjct: 21084 KVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNI 21143
Query: 1051 NMEDKATLVLQVVDKPSPPQ-DLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKT 1109
E + +QV D P PP ++ + V W PP++ G + Y V+ +
Sbjct: 21144 VGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDS 21203
Query: 1110 MEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVG 1146
W + RT L G Y FRV +QN G
Sbjct: 21204 TTWVELATTVIRTTYKATRLTTGLEYQFRVKAQNRYG 21240
Score = 209 bits (531), Expect = 2e-53
Identities = 164/608 (26%), Positives = 257/608 (42%), Gaps = 65/608 (10%)
Query: 577 WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKI 636
W K E+V S + V L I DVT D YS E S+ ++K+
Sbjct: 18932 WKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAEN-----SSGTDTQKIKV 18986
Query: 637 DFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKA-ITQGNKAPA 695
+ PP+ D I D + + G I +K +++G
Sbjct: 18987 VVMDAPGPPQPPFD----ISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRG----- 19037
Query: 696 RPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKN 755
+WV + +T RV + G E ++ V +N
Sbjct: 19038 --------------DWVTALASVTKTSCRVGK---------LIPGQEY----IFRVRAEN 19070
Query: 756 PVGEDQVNLTVKVI-----DVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILER 810
G + + K++ VP P +++ V +D V W+ P DGG PI+GY++ER
Sbjct: 19071 RFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIER 19130
Query: 811 KKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQ---PFMPI 867
K++ S W++ N L++ + ++EG+ Y R+YA+N G S PS ++ MP+
Sbjct: 19131 KERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPV 19190
Query: 868 GPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTE-- 925
PP +P V DV+ +TVSL W P+ G + GY VE C +WV +
Sbjct: 19191 DPPGKP---EVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIP 19247
Query: 926 HTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQK 985
L A+ FR A P ++PVT+ PR+ L ++ +
Sbjct: 19248 QEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVAMKSLLTV 19307
Query: 986 KVGEPVNLLIPFQGKPRPQVTWTKEG---QPLAGEEVSIRNSPTDTILFIRAARRVHSGT 1042
K G V L GKP P V+W K+G +P G +++++ + LF + R SG
Sbjct: 19308 KAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELF--SVNRKDSGD 19365
Query: 1043 YQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTV 1102
Y +T + AT+ L+V+DKP PP +++ + L W+PP + G +E+ Y V
Sbjct: 19366 YTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIV 19425
Query: 1103 QKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPR 1162
K + W V T C V +LI G+ Y FR+ ++N G D T EP
Sbjct: 19426 DKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFT--EPAIAKN 19483
Query: 1163 PGITYEPP 1170
P Y+PP
Sbjct: 19484 P---YDPP 19488
Score = 207 bits (526), Expect = 7e-53
Identities = 139/404 (34%), Positives = 194/404 (48%), Gaps = 13/404 (3%)
Query: 771 VPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELS 830
VPDAP P ++ V +DS V W P +DGG+PI YILE+++ S RW R+ D I +
Sbjct: 17011 VPDAPDQPIVTEVTKDSALVTWNKP-HDGGKPITNYILEKRETMSKRWARVTKDPIHPYT 17069
Query: 831 H-EARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PIGPPSEPTHLAVEDVSDTTV 886
++EG YE RV A N IG+ PSP S+P PI PS P + D + +V
Sbjct: 17070 KFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSV 17129
Query: 887 SLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAA--LQGLTEHTSILVKDLPTGARLLFRV 944
L W+PP G + GY VEY G EW A T V L G FRV
Sbjct: 17130 DLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRV 17189
Query: 945 RAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQ 1004
A N AG P EPV V++ L+ P L L ++ + KVG+ + L +G P P+
Sbjct: 17190 LAVNAAGESDPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPK 17249
Query: 1005 VTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVD 1064
VTW KE + A + I +P + L IR A G Y +TV ++ + V+D
Sbjct: 17250 VTWKKEDRD-APTKARIDVTPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLD 17308
Query: 1065 KPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHC 1124
KP PP+DL V++ + L WK P D G + + Y V++ D + +W + ++
Sbjct: 17309 KPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSH 17368
Query: 1125 VVPELIIGNGYYFRVFSQNMVGFSDRAATTK-----EPVFIPRP 1163
L GN Y FRV ++N G T K +P+ P P
Sbjct: 17369 FAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGP 17412
Score = 206 bits (524), Expect = 1e-52
Identities = 169/608 (27%), Positives = 260/608 (42%), Gaps = 74/608 (12%)
Query: 577 WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFV---PEGFACNLSAKLHFME 633
W K+GKEL +++++ L D T D Y+ P GFA H
Sbjct: 21495 WSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGGFA------KHIFN 21548
Query: 634 VKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKA 693
VK+ LD PG P G A T + + K
Sbjct: 21549 VKV------------LDRPG------------------PPEGPLAVTEVTSE------KC 21572
Query: 694 PARPAPDAPEDTGDSDEWVFDKK---LLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYT 750
P + D ++ K+ L T V+ TK + ++G +E ++
Sbjct: 21573 VLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKG----NEYIFR 21628
Query: 751 VTVKNPVG-----EDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILG 805
V N G E + L V PD P P+++ + +DS V W P DGG I+
Sbjct: 21629 VMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIIN 21688
Query: 806 YILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM 865
YI+ER+ K RW++ N + +L ++ + EG YE R+ A NA G+S PSP S PF
Sbjct: 21689 YIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTS-PFY 21747
Query: 866 PI-------GPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEW-- 916
GPP P V D S +++S+ W P G + GY VE EW
Sbjct: 21748 KACDTVFKPGPPGNP---RVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQI 21804
Query: 917 VAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLP 976
V GL + TS + L R+ A N G G P ++ + P ++L
Sbjct: 21805 VTPPAGL-KATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEIELD 21863
Query: 977 RHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKE-GQPLAGEEVSIRNSPTDTILFIRAA 1035
LR+ + + + L +P +G+P P+V W ++ G+ L ++ SI ++ + T+L +
Sbjct: 21864 ADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDHGESL--DKASIESTSSYTLLIVGNV 21921
Query: 1036 RRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNT 1095
R SG Y +TV + A + ++V+D P PPQDL+V + +V L W PP G +
Sbjct: 21922 NRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGS 21981
Query: 1096 ELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTK 1155
++ Y V+K + + TV + +T V +L G YYFRV ++N G A T +
Sbjct: 21982 KIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAE 22041
Query: 1156 EPVFIPRP 1163
RP
Sbjct: 22042 SVKASERP 22049
Score = 205 bits (522), Expect = 2e-52
Identities = 166/590 (28%), Positives = 260/590 (44%), Gaps = 57/590 (9%)
Query: 577 WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKI 636
W K+G L P IK++ + L + V D DY+ E + + SA + ++K+
Sbjct: 19329 WKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATI---KLKV 19385
Query: 637 DFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPAR 696
LD PG P V + NK+ D + + W+ + G
Sbjct: 19386 ------------LDKPG--PPASVKI--NKMYSDRAM-------LSWEPPLEDGGS---- 19418
Query: 697 PAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNP 756
+ ++ DK+ +V T + +VE + E + + +N
Sbjct: 19419 ----------EITNYIVDKRETSRPNW-AQVSATVPITSCSVEKLIEGHEYQFRICAENK 19467
Query: 757 VGEDQVNLTVKVI-----DVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERK 811
G T I D P P ISN+ +D TV W+PPA DGG PI GY+LE++
Sbjct: 19468 YGVGDPVFTEPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKR 19527
Query: 812 KKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQ------PFM 865
+ ++ W ++N I E + +A + EG YE RV A+N G +PS AS+ P
Sbjct: 19528 ETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQY 19587
Query: 866 PIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAA-LQGLT 924
P GPP+ P V D + ++VSL W P G + GY VE WV L
Sbjct: 19588 PPGPPAFP---KVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNL 19644
Query: 925 EHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQ 984
+ T V L + FRV A N G P + ++IL P +L LR+T+
Sbjct: 19645 QKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLI 19704
Query: 985 KKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGE-EVSIRNSPTDTILFIRAARRVHSGTY 1043
+ G + L +P +G+P P++TW+K L + I+++ DT L + +G Y
Sbjct: 19705 LRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKY 19764
Query: 1044 QVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQ 1103
+T+ + + T+V++V+D P PP ++ V + + + W+PP G + + Y VQ
Sbjct: 19765 ILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQ 19824
Query: 1104 KADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAAT 1153
K D + W TV +T V L G Y+FRVF++N G D T
Sbjct: 19825 KRDAERKSWSTVTTECSKTSFRVANLEEGKSYFFRVFAENEYGIGDPGET 19874
Score = 204 bits (519), Expect = 4e-52
Identities = 155/574 (27%), Positives = 256/574 (44%), Gaps = 43/574 (7%)
Query: 632 MEVKIDFVPRQEPPKIHLDCPGRIPD---TIVVVAGNKL-----RLDVPISGDPAPTVIW 683
+++ + V R E K L P + + T V A N+L + V + P+P
Sbjct: 15446 LQITKEEVSRSEA-KTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPR-- 15502
Query: 684 QKAITQGNKAPARPAPDAPEDTGDSD--EWVFDKKLLCETEGR-VRVETTKDRSIFTVEG 740
A+T DAP D G S+ +V DK+ + V T + +
Sbjct: 15503 NLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWK 15562
Query: 741 AEKEDEGVYTVTVKNPVGEDQVNLTVKVI-----DVPDAPAAPKISNVGEDSCTVQWEPP 795
+ + V N G + KV+ +P P PK+ + S V W PP
Sbjct: 15563 LIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPP 15622
Query: 796 AYDGGQPILGYILERKKKKSYRWMRLNFDLIQELS-----HEARRMIEGVVYEMRVYAVN 850
+GG PI GY LE++++ S W R++ I ++ R++EGV Y+ R A+N
Sbjct: 15623 LDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAIN 15682
Query: 851 AIGMSRPSPASQPFM---PIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVE 907
A G+ PS S P + PI PP P+ V+D + +++SL W+PP + G + GY VE
Sbjct: 15683 AAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVE 15742
Query: 908 YCPEGCSEW--VAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQ 965
EG ++W V L +V +L + FRV+A N AG P TT +
Sbjct: 15743 MQEEGTTDWKRVNEPDKLITTCECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPAT 15802
Query: 966 EILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSP 1025
+I + P + + + + K G + + +G+P P+ +W +G+ + + + P
Sbjct: 15803 DIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIP 15862
Query: 1026 TD---------TILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTD 1076
D +++ I +R H+G Y +T + + + A ++V+D P PP+DL+V+D
Sbjct: 15863 EDAQLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDLKVSD 15922
Query: 1077 AWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYY 1136
+ L WK P D G + GY ++K W V T VVP+L+ Y+
Sbjct: 15923 ITRGSCRLSWKMPDDDGGDRIKGYVIEKRTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYF 15982
Query: 1137 FRVFSQNMVGFSD-----RAATTKEPVFIPRPGI 1165
FRV ++N G + T ++P++ P P I
Sbjct: 15983 FRVRAENRFGIGPPVETIQRTTARDPIYPPDPPI 16016
Score = 203 bits (516), Expect = 1e-51
Identities = 156/577 (27%), Positives = 241/577 (41%), Gaps = 75/577 (12%)
Query: 659 IVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLL 718
I+V+ G KL + VP P PTV W K D E
Sbjct: 14396 IIVIEGEKLSIPVPFRAVPVPTVSWHK---------------------DGKE-------- 14426
Query: 719 CETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAP 778
+ R+ ++ + V + + D G+YT+T++N +G ++ VKVI +P
Sbjct: 14427 VKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKDI 14486
Query: 779 KISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIE 838
K S++ + SC + WEPP +DGG PIL Y+LER++ ++ + +LS + +I
Sbjct: 14487 KASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPV-MSGENKLSWTVKDLIP 14545
Query: 839 GVVYEMRVYAVNAIGMSRPSPASQPFM---PIGPPSEPTHLAVEDVSDTTVSLKWRPPER 895
Y RV AVN +G P + P PP P + V + + +++ W+PP
Sbjct: 14546 NGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITWKPPLY 14605
Query: 896 VGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAP 955
G + GY +E +G W + L + K L G FRVRA N AG P
Sbjct: 14606 DGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTYTAKGLEEGKEYQFRVRAENAAGISEP 14665
Query: 956 VTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLA 1015
T P + + P++ L R +++ K G+ + L G P P +TW K+ +
Sbjct: 14666 SRATPPTKAVDPIDAPKVIL----RTSLEVKRGDEIALDASISGSPYPTITWIKDENVIV 14721
Query: 1016 GEEVSIRNSPT------------------------------DTILFIRAARRVHSGTYQV 1045
EE+ R +P ++ L +R + R G Y +
Sbjct: 14722 PEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMI 14781
Query: 1046 TVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKA 1105
V ++ KA + V+D P PP + D +V +W+PP D G +E+ YT++K
Sbjct: 14782 KVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCKWEPPLDDGGSEIINYTLEKK 14841
Query: 1106 D--KKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVG----FSDRAATTKEPVF 1159
D K EW V R V +LI G Y FRV ++N G + K+P F
Sbjct: 14842 DKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKPLVAKDP-F 14900
Query: 1160 IPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGY 1196
P P +P S + +P N S I GY
Sbjct: 14901 GP-PDAPDKPIVEDVTSNSMLVKWNEPKDNGSPILGY 14936
Score = 202 bits (514), Expect = 2e-51
Identities = 143/504 (28%), Positives = 223/504 (44%), Gaps = 23/504 (4%)
Query: 727 VETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGE----DQVNLTVKV-IDVPDAPAAPKIS 781
V T R++ V +E + + +N G D +TVK+ P P+ P ++
Sbjct: 26620 VSATVARTMMKVMKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVT 26679
Query: 782 NVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVV 841
NV +S TV W P +GG ++GY LE K + S W + N +I+ + + G++
Sbjct: 26680 NVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLI 26739
Query: 842 YEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGL 901
YE RVYA NA G+ +PS S+P + I P ++ + D+S +VSL W+ P G +
Sbjct: 26740 YEFRVYAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKI 26799
Query: 902 DGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGP-GAPVTTTE 960
GY VE W A T ++ L ++ FRV A N G P
Sbjct: 26800 TGYIVERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVG 26859
Query: 961 PVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPL-AGEEV 1019
P+T + P + LP + ++ + G V L GKP P + W K+ + L V
Sbjct: 26860 PITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALV 26919
Query: 1020 SIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPP-QDLRVTDAW 1078
+ N+ + I+ A R++SG Y++ +R AT+ +Q++DKP PP +
Sbjct: 26920 CVENTTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVT 26979
Query: 1079 GLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFR 1138
+ L W+PP D G ++ Y V+K + + W V EH ++I GN Y FR
Sbjct: 26980 AEKITLLWRPPADDGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFR 27039
Query: 1139 VFSQNMVGF-----SDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVN-RSV 1192
V + N G SD V PGI P K S +++P+ + S
Sbjct: 27040 VRAVNKYGIGEPLESDSVVAKNAFVTPGPPGI---PEVTKITKNSMTVVWSRPIADGGSD 27096
Query: 1193 IAGYTAMLCCAVRGSPKPKISWFK 1216
I+GY + K + WFK
Sbjct: 27097 ISGY------FLEKRDKKSLGWFK 27114
Score = 202 bits (513), Expect = 2e-51
Identities = 144/471 (30%), Positives = 207/471 (43%), Gaps = 23/471 (4%)
Query: 683 WQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAE 742
W+ + G + + T EW+ L + V +F V
Sbjct: 14822 WEPPLDDGGSEIINYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAEN 14881
Query: 743 KEDEGVYTVT----VKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYD 798
+ G V+ K+P G PDAP P + +V +S V+W P D
Sbjct: 14882 RFGPGPPCVSKPLVAKDPFGP------------PDAPDKPIVEDVTSNSMLVKWNEPK-D 14928
Query: 799 GGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPS 858
G PILGY LE+++ S W R+N L+ L ++EG+ Y RV A NA G + S
Sbjct: 14929 NGSPILGYWLEKREVNSTHWSRVNKSLLNALKANVDGLLEGLTYVFRVCAENAAGPGKFS 14988
Query: 859 PASQP---FMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSE 915
P S P PI PP P V D S TT+ L+W PP G G + GY V+ G +E
Sbjct: 14989 PPSDPKTAHDPISPPGPPIP-RVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNE 15047
Query: 916 WVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQL 975
W + + + VK++ GA RV A N AG G P T+PVTV E + P ++L
Sbjct: 15048 WSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGEGPP-GETQPVTVAEPQEPPAVEL 15106
Query: 976 PRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAA 1035
++ IQ G+ + + G+P P WTKE L + V I N T + L I+ A
Sbjct: 15107 DVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGTKSELIIKDA 15166
Query: 1036 RRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNT 1095
R G Y +T A ++V D P P DL+ L W P+D G +
Sbjct: 15167 LRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGS 15226
Query: 1096 ELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVG 1146
E+ G+ +++ D K W +E R+ C + L+ G Y FRV ++N G
Sbjct: 15227 EITGFIIERKDAKMHTWRQPIE-TERSKCDITGLLEGQEYKFRVIAKNKFG 15276
Score = 201 bits (512), Expect = 3e-51
Identities = 169/574 (29%), Positives = 245/574 (42%), Gaps = 58/574 (10%)
Query: 642 QEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDA 701
QEPP + LD + I ++AG LR+ ++G P PT +W K
Sbjct: 15099 QEPPAVELDVS--VKGGIQIMAGKTLRIPAVVTGRPVPTKVWTK---------------- 15140
Query: 702 PEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQ 761
+E DK RV ++ +S ++ A ++D G Y +T N G
Sbjct: 15141 -------EEGELDKD-------RVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKF 15186
Query: 762 VNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRL 821
V+V DVP K C + W P DGG I G+I+ERK K + W +
Sbjct: 15187 AAARVEVFDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFIIERKDAKMHTWRQ- 15245
Query: 822 NFDLIQELSH-EARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PIGPPSEPTHLA 877
+ E S + ++EG Y+ RV A N G P P + P+GPP+ P L
Sbjct: 15246 --PIETERSKCDITGLLEGQEYKFRVIAKNKFGCGPPVEIG-PILAVDPLGPPTSPERLT 15302
Query: 878 VEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTG 937
+ + +T++L W+ P G + GY +E ++ + L TS LV++L
Sbjct: 15303 YTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEH 15362
Query: 938 ARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLR-QTIQKKVGEPVNLLIP 996
FRV+A N G P V +Q+ P ++L +R TI+ K GEPV++
Sbjct: 15363 QMYEFRVKAVNEIGESEPSLPLN-VVIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPAD 15421
Query: 997 FQGKPRPQVTWTK---------EGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTV 1047
G P P++ W+K + + EEVS S T L I A R GTY VT
Sbjct: 15422 VTGLPMPKIEWSKNETVIEKPTDALQITKEEVS--RSEAKTELSIPKAVREDKGTYTVTA 15479
Query: 1048 RIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKAD- 1106
+ ++V D+PSPP++L VTD + L W P D G +E+ Y + K D
Sbjct: 15480 SNRLGSVFRNVHVEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDA 15539
Query: 1107 -KKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIP--RP 1163
+K EW V + +LI Y FRV + N G SD + K + P P
Sbjct: 15540 SRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLP 15599
Query: 1164 GITYEPPNYKALDFSEAPSFTQPLVN-RSVIAGY 1196
G +P S S+T PL N S I GY
Sbjct: 15600 GPPGKPKVLARTKGSMLVSWTPPLDNGGSPITGY 15633
Score = 201 bits (511), Expect = 4e-51
Identities = 166/600 (27%), Positives = 260/600 (43%), Gaps = 71/600 (11%)
Query: 577 WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKI 636
W K GK++ P +++ LTI T D +Y+ K+ ++V +
Sbjct: 20413 WSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATN---PFGTKVEHVKVTV 20469
Query: 637 DFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPAR 696
LDVP G P P I + KA
Sbjct: 20470 --------------------------------LDVP--GPPGPVEI---SNVSAEKATLT 20492
Query: 697 PAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKD----RSIFT--VEGAEKEDEGVYT 750
P + ++ +K+ ET + ++D R + T ++G +E ++
Sbjct: 20493 WTPPLEDGGSPIKSYILEKR---ETSRLLWTVVSEDIQSCRHVATKLIQG----NEYIFR 20545
Query: 751 VTVKNPVGEDQV--NLTVKVID---VPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILG 805
V+ N G+ + + VK++D P P P++SNV +++ TV W+ P DGG I G
Sbjct: 20546 VSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITG 20605
Query: 806 YILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM 865
Y +ER++KKS RW+R + +L + + EG YE RV A N G+ PS AS +
Sbjct: 20606 YHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVL 20665
Query: 866 ------PIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAA 919
P GPPS P V D + + SL W P G + GY VE+ G W+
Sbjct: 20666 MKDAAYPPGPPSNP---HVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKD 20722
Query: 920 LQGLT-EHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRH 978
G T +V DL T + FR+ A N AG G P + V + E P +L
Sbjct: 20723 TTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVIPD-VEIVEREMAPDFELDAE 20781
Query: 979 LRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRV 1038
LR+T+ + G + + +P +G+P P+VTWTK+ L +I N+ + T+L I R
Sbjct: 20782 LRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLK-NRANIENTESFTLLIIPECNRY 20840
Query: 1039 HSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELW 1098
+G + +T+ + + ++V+D P P +LR TD +V L W P G + +
Sbjct: 20841 DTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRIT 20900
Query: 1099 GYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPV 1158
Y V+K + + T + V L G Y+FRV ++N G + TT EPV
Sbjct: 20901 NYIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETT-EPV 20959
Score = 200 bits (508), Expect = 8e-51
Identities = 169/607 (27%), Positives = 252/607 (41%), Gaps = 59/607 (9%)
Query: 574 RGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFME 633
R W K+G E+ ++++ + L + D T Y+ + + + A++ +
Sbjct: 27989 RVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEI---K 28045
Query: 634 VKIDFVPRQEPPKIHLDCPGRI--PDTIVVVAGNKLRL--DVPISGDPAPTV--IWQKAI 687
VK+ D PG++ P + G K+ L D P++ AP I +K
Sbjct: 28046 VKVQ------------DTPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRE 28093
Query: 688 TQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEG 747
T +R A ED ++ + K L+ E + RV
Sbjct: 28094 T------SRLAWALIEDKCEAQSYTAIK-LINGNEYQFRVSA------------------ 28128
Query: 748 VYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYI 807
V V P+ D V ++ VPDAP P+ SN+ +S T+ W P DGG I YI
Sbjct: 28129 VNKFGVGRPLDSDPVVAQIQYT-VPDAPGIPEPSNITGNSITLTWARPESDGGSEIQQYI 28187
Query: 808 LERKKKKSYRWMR-LNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM- 865
LER++KKS RW++ ++ I E + + EG YE V A NA G+ S S+
Sbjct: 28188 LERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKC 28247
Query: 866 --PIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGL 923
P+ PP PT + V D S TTVSL+W P G + GY +E C +W
Sbjct: 28248 REPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEA 28307
Query: 924 TEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTI 983
T V DL G FRV A N AG G T + + L P L + + +QT
Sbjct: 28308 CVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTH 28367
Query: 984 QKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTY 1043
+ G + L I +QG+P P W+K L+ I + + + L + R +G Y
Sbjct: 28368 VVRAGASIRLFIAYQGRPTPTAVWSKPDSNLS-LRADIHTTDSFSTLTVENCNRNDAGKY 28426
Query: 1044 QVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQ 1103
+TV + T ++V+D P PP + D + L W P G + Y V+
Sbjct: 28427 TLTVENNSGSKSITFTVKVLDTPGPPGPITFKDVTRGSATLMWDAPLLDGGARIHHYVVE 28486
Query: 1104 KADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRP 1163
K + W + E R V +L G YYFRV + N G EP +P P
Sbjct: 28487 KREASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVG-------EPYEMPEP 28539
Query: 1164 GITYEPP 1170
+ E P
Sbjct: 28540 IVATEQP 28546
Score = 199 bits (507), Expect = 1e-50
Identities = 128/407 (31%), Positives = 195/407 (47%), Gaps = 14/407 (3%)
Query: 771 VPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELS 830
VP P P+++ V +DS T+ W P DGG PILGY +ERK++ W ++ L+
Sbjct: 21258 VPGPPGTPQVTAVTKDSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNI 21317
Query: 831 HEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PIGPPSEPTHLAVEDVSDTTVS 887
++ + +G+ YE RV A N G S+PS S+P + PI PP +P L +++ TV+
Sbjct: 21318 FKSSGLTDGIAYEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPL---NITRHTVT 21374
Query: 888 LKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAH 947
LKW PE G + Y VE W+ A V L A FRV A
Sbjct: 21375 LKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAK 21434
Query: 948 NMAGP-GAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVT 1006
N AG P ++ +T ++ ++ P++++ + T+ K GE L G+P P +
Sbjct: 21435 NAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTME 21494
Query: 1007 WTKEGQPLAG-EEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDK 1065
W+K+G+ L G ++ I+ + T L + + R SG Y +T K ++V+D+
Sbjct: 21495 WSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDR 21554
Query: 1066 PSPPQ-DLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHC 1124
P PP+ L VT+ L W PP D G ++ Y VQK + + W V + T
Sbjct: 21555 PGPPEGPLAVTEVTSEKCVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKL 21614
Query: 1125 VVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPN 1171
V +L+ GN Y FRV + N G + EPV P Y PP+
Sbjct: 21615 KVTKLLKGNEYIFRVMAVNKYGVGE--PLESEPVLAVNP---YGPPD 21656
Score = 199 bits (506), Expect = 1e-50
Identities = 156/565 (27%), Positives = 253/565 (44%), Gaps = 26/565 (4%)
Query: 702 PEDTGDSD--EWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGE 759
P+D G S+ ++ +K+ + V + ++ F V + E + V+ +N G
Sbjct: 20100 PKDDGGSEITNYILEKRDSVNNKW-VTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGV 20158
Query: 760 DQVNLTVKVI-----DVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKK 814
+ + ++ DVPDAP P I +V DS ++ W P GG PI GY LE K++
Sbjct: 20159 GEGLKSEPIVARHPFDVPDAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERN 20218
Query: 815 SYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPT 874
S W R N I+ + + EG+ YE RV A+N G+ +PS S+P + + P P
Sbjct: 20219 SLLWKRANKTPIRMRDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPG 20278
Query: 875 HLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDL 934
V +++ +V+L W P+ G L GY VE W+ A + V DL
Sbjct: 20279 KPEVINITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDL 20338
Query: 935 PTGARLLFRVRAHNMAGP-GAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNL 993
G + FR+RA N AG AP +TE + ++ + P + L ++ + K G+ + L
Sbjct: 20339 VEGGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVL 20398
Query: 994 -LIPFQGKPRPQVTWTKEGQPLAGEEVS-IRNSPTDTILFIRAARRVHSGTYQVTVRIEN 1051
I GKP P+ +W+K G+ + +++ I ++PT ++L I+ A R +G Y +T
Sbjct: 20399 NAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPF 20458
Query: 1052 MEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTME 1111
+ + V+D P PP + +++ L W PP + G + + Y ++K + +
Sbjct: 20459 GTKVEHVKVTVLDVPGPPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLL 20518
Query: 1112 WFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPV-----FIPRPGIT 1166
W V E + V +LI GN Y FRV + N G + EPV F P PG
Sbjct: 20519 WTVVSEDIQSCRHVATKLIQGNEYIFRVSAVNHYGKGE--PVQSEPVKMVDRFGP-PGPP 20575
Query: 1167 YEPPNYKALDFSEAPSFTQPLVN-RSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDA 1225
+P + S+ +P+ + S I GY V K + W + D
Sbjct: 20576 EKPEVSNVTKNTATVSWKRPVDDGGSEITGY------HVERREKKSLRWVRAIKTPVSDL 20629
Query: 1226 RFRMFSKQGVLTLEIRKPCPFDGGI 1250
R ++ Q T E R GI
Sbjct: 20630 RCKVTGLQEGSTYEFRVSAENRAGI 20654
Score = 197 bits (500), Expect = 7e-50
Identities = 147/509 (28%), Positives = 216/509 (42%), Gaps = 42/509 (8%)
Query: 644 PPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPE 703
PP++ LD R D I V G +R+ + G P P + W K
Sbjct: 17905 PPEVELDVTCR--DVITVRVGQTIRILARVKGRPEPDITWTK------------------ 17944
Query: 704 DTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVN 763
+ K+L E RV + R ++ A + D G Y ++ KN G Q +
Sbjct: 17945 ----------EGKVLVR-EKRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSGHAQGS 17993
Query: 764 LTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNF 823
V V+D P K++NV +++CT+ WE P +GG I +I+E +K W +
Sbjct: 17994 AIVNVLDRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIVEYRKPNQKGWSIVAS 18053
Query: 824 DLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGP---PSEPTHLAVED 880
D+ + L ++ Y RV A N +G+ P + I P P EP +L + D
Sbjct: 18054 DVTKRLIKA--NLLANNEYYFRVCAENKVGVGPTIETKTPILAINPIDRPGEPENLHIAD 18111
Query: 881 VSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARL 940
T V LKWR P+ G Y VE +G +W +G + T +V
Sbjct: 18112 KGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVENQIY 18171
Query: 941 LFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGK 1000
FRV+ N G V T E V V+E LQ+P L L L + K G+ + L +GK
Sbjct: 18172 EFRVQTKNEGGESDWVKTEE-VVVKEDLQKPVLDLK--LSGVLTVKAGDTIRLEAGVRGK 18228
Query: 1001 PRPQVTWTKEGQPL---AGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKAT 1057
P P+V WTK+ V I + + A+R G Y VT A
Sbjct: 18229 PFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAY 18288
Query: 1058 LVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLE 1117
+ V+DKP P ++L++ D + W PP+D G E+ Y ++K + K M W T
Sbjct: 18289 ATVNVLDKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSA 18348
Query: 1118 HYRRTHCVVPELIIGNGYYFRVFSQNMVG 1146
V LI GN Y FRV ++N +G
Sbjct: 18349 TVLTPGTTVTRLIEGNEYIFRVRAENKIG 18377
Score = 196 bits (498), Expect = 1e-49
Identities = 146/539 (27%), Positives = 227/539 (42%), Gaps = 73/539 (13%)
Query: 635 KIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAP 694
+I V QE P+I LD ++ + V AG K+ L ++G P P + W KA
Sbjct: 13678 EIQAVDTQEAPEIFLDV--KLLAGLTVKAGTKIELPATVTGKPEPKITWTKA-------- 13727
Query: 695 ARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVK 754
++ + + R+ +E +S T+ +++ D G Y +
Sbjct: 13728 ---------------------DMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAV 13766
Query: 755 NPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKK 814
N G + V V+D P PAA I++V +SC + W PP DGG I Y++ER+
Sbjct: 13767 NVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATD 13826
Query: 815 SYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRP---SPASQPFMPIGPPS 871
S W +L+ +++ + +A ++I Y RV A N G+ P SP + + PP
Sbjct: 13827 SEVWHKLS-STVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITAKYQ-FDPPG 13884
Query: 872 EPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILV 931
PT L D++ V+L W P+ G + GY VE +WV + + T+ V
Sbjct: 13885 PPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRV 13944
Query: 932 KDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPV 991
K L + FRV A N+AGPG P +TEP+ +++ + P P
Sbjct: 13945 KGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPP----------------WPPG 13988
Query: 992 NLLIPFQGKPRPQVTWTKEGQPLAG--EEVSIRNSPTDTILFIRAARRV----------- 1038
+ GK ++ WTK E I T T ++R A V
Sbjct: 13989 KPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVPTTQHLLPGLM 14048
Query: 1039 HSGTYQVTVRIENMEDKA--------TLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQ 1090
Y VR N ++ L + + PSPP+ L V + L+W P+
Sbjct: 14049 EGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPE 14108
Query: 1091 DVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSD 1149
G + + Y V+K D + W TV + T C V L G+ Y FRV ++N +G SD
Sbjct: 14109 KDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSD 14167
Score = 196 bits (498), Expect = 1e-49
Identities = 162/633 (25%), Positives = 260/633 (41%), Gaps = 83/633 (13%)
Query: 642 QEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDA 701
QE P++ +D + D +V AG+++R+ I G P P W+ + KA D
Sbjct: 15805 QEEPEVFIDIGAQ--DCLVCKAGSQIRIPAVIKGRPTPKSSWEFD-GKAKKAMKDGVHDI 15861
Query: 702 PEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQ 761
PED ++ET ++ S+ + ++ G Y++T KN G+
Sbjct: 15862 PEDA--------------------QLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKT 15901
Query: 762 VNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRL 821
N VKV+DVP P K+S++ SC + W+ P DGG I GY++E++ W ++
Sbjct: 15902 ANCRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKRTIDGKAWTKV 15961
Query: 822 NFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PIGPPSEPTHLAV 878
N D + ++ Y RV A N G+ P Q PI PP P L +
Sbjct: 15962 NPDC-GSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKI 16020
Query: 879 EDVSDTTVSLKWRPPERVGAGGLDGYSVE---YCPEGCSE--WVAALQGLTEHTSILVKD 933
++ TV L W+PP+ G + Y VE + P G + W + E V+D
Sbjct: 16021 GLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVED 16080
Query: 934 LPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNL 993
L G FRV+A N AG P T P Q RP + L++ ++ + G VN+
Sbjct: 16081 LVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQ----RPDMPPSIDLKEFMEVEEGTNVNI 16136
Query: 994 LIPFQGKPRPQVTWTK-------EGQPLAGEEVSIRNSPTDTI-LFIRAARRVHSGTYQV 1045
+ +G P P +TW K +P+ + + DT L I +RR +G Y +
Sbjct: 16137 VAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTI 16196
Query: 1046 TVRIENMEDKATLVLQVVDKPSPPQD-LRVTDAWGLNVALEWKPPQDVGNTELWGYTVQK 1104
T + L V+ +P PP ++ + L W PP+D G +++ Y ++K
Sbjct: 16197 TAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIEK 16256
Query: 1105 ADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPV--FIPR 1162
+ W V + +P+L+ G+ Y FR+ +QN G + + E
Sbjct: 16257 REANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFSV 16316
Query: 1163 PG----------------ITYEPPNYKA--------LDFSEAPSFTQPLVNRSVIAGYTA 1198
PG + +E P Y L+ + S VNR I T
Sbjct: 16317 PGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMTL 16376
Query: 1199 MLCCAVRGSPKPKISWFKNGLDLGEDARFRMFS 1231
+S+ GL G D +FR+++
Sbjct: 16377 ------------GVSYKVTGLIEGSDYQFRVYA 16397
Score = 195 bits (495), Expect = 3e-49
Identities = 127/403 (31%), Positives = 185/403 (45%), Gaps = 20/403 (4%)
Query: 772 PDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSH 831
P P+ P++S + +DS V W P DGG I GYILE++ K+ RW + N + +L
Sbjct: 24902 PGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLTDLRL 24961
Query: 832 EARRMIEGVVYEMRVYAVNAIGMSRPSP------ASQPFMPIGPPSEPTHLAVEDVSDTT 885
+ EG YE RV A NA G+ PS A P GPPS P V D S ++
Sbjct: 24962 RVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNP---KVTDTSRSS 25018
Query: 886 VSLKWRPPERVGAGGLDGYSVEYCPEGCSEWV-----AALQGLTEHTSILVKDLPTGARL 940
VSL W P G + GY VE EW LQG V L
Sbjct: 25019 VSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQG----KQFTVTKLKENTEY 25074
Query: 941 LFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGK 1000
FR+ A N G G P T V QE ++ P ++L LR+ + + + L + +G+
Sbjct: 25075 NFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRASATLRLFVTIKGR 25134
Query: 1001 PRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVL 1060
P P+V W K + + + I + + T+L I R SG Y +T+ + A + +
Sbjct: 25135 PEPEVKWEK-AEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSGSKTAFVNV 25193
Query: 1061 QVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYR 1120
+V+D PS P +L + + +V L W+PP G ++ Y V+K + + T+ +
Sbjct: 25194 RVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATITNNCT 25253
Query: 1121 RTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRP 1163
+T + L G YYFRV + N G A TT EPV + P
Sbjct: 25254 KTTFRIENLQEGCSYYFRVLASNEYGIGLPAETT-EPVKVSEP 25295
Score = 191 bits (485), Expect = 4e-48
Identities = 129/467 (27%), Positives = 213/467 (45%), Gaps = 18/467 (3%)
Query: 772 PDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSH 831
P P P + + +DS +QW P +GG P++GY LERK++ S W ++N +I +
Sbjct: 23423 PGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQF 23482
Query: 832 EARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PIGPPSEPTHLAVEDVSDTTVSL 888
+A+ + EG+ YE RVYA N +G+ + S S+ ++ P PP P + V+ ++L
Sbjct: 23483 KAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPPGTPEPIMVK---RNEITL 23539
Query: 889 KWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHN 948
+W P G + GY VE W+ A T V L R FRV A N
Sbjct: 23540 QWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKN 23599
Query: 949 MAGP-GAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTW 1007
AG P +T P+T ++ ++ PR+ + R TI GE L GKP P + W
Sbjct: 23600 AAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEW 23659
Query: 1008 TKEGQPL-AGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKAT--LVLQVVD 1064
+ + + I+N+ +L ++ A R+ G Y +R N+ + + ++V+D
Sbjct: 23660 LRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQY--ILRASNVAGSKSFPVNVKVLD 23717
Query: 1065 KPSPPQ-DLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTH 1123
+P PP+ ++VT +L W PP G +++ Y V+K + + W V
Sbjct: 23718 RPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNS 23777
Query: 1124 CVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSF 1183
V +L+ GN Y FR+ + N G + + PV + P + PP K+L+ +
Sbjct: 23778 LKVTKLLEGNEYVFRIMAVNKYGVGEPLESA--PVLMKNPFVLPGPP--KSLEVTNIAKD 23833
Query: 1184 TQPLV-NRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRM 1229
+ + NR G + ++ V + I W K D R R+
Sbjct: 23834 SMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRV 23880
Score = 189 bits (480), Expect = 1e-47
Identities = 125/408 (30%), Positives = 194/408 (47%), Gaps = 15/408 (3%)
Query: 771 VPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELS 830
VP P P ++ DS VQW P DGG ++GY LERK++ S W++LN I +
Sbjct: 22340 VPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTK 22399
Query: 831 HEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PIGPPSEPTHLAVEDVSDTTVS 887
+ + EGV YE RV A N +G+ +PS S+ ++ P PP P + V+ +V+
Sbjct: 22400 FKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAII---VTRNSVT 22456
Query: 888 LKWRPPERVGAGGLDGYSVE--YCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVR 945
L+W+ P G + GY VE PEG W+ A T V L R FRV
Sbjct: 22457 LQWKKPTYDGGSKITGYIVEKKELPEG--RWMKASFTNIIDTHFEVTGLVEDHRYEFRVI 22514
Query: 946 AHNMAGP-GAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQ 1004
A N AG P +T +T ++ + PR+ + + TI GE + GKP P
Sbjct: 22515 ARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPT 22574
Query: 1005 VTWTKEGQPLAG-EEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVV 1063
+ W K Q L+ + I+++ T L ++ A RV SG Y + + E T+ ++V+
Sbjct: 22575 IQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVL 22634
Query: 1064 DKPSPPQ-DLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRT 1122
D+P PP+ + ++ L WKPP G +++ Y V++ + + W V + +
Sbjct: 22635 DRPGPPEGPVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTL 22694
Query: 1123 HCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPP 1170
C V +L+ GN Y FR+ + N G + EPV P + + P
Sbjct: 22695 SCKVTKLLEGNEYTFRIMAVNKYGVGE--PLESEPVVAKNPFVVPDAP 22740
Score = 189 bits (479), Expect = 2e-47
Identities = 129/478 (26%), Positives = 224/478 (46%), Gaps = 24/478 (5%)
Query: 743 KEDEGVYTVTVKNPVG-----EDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAY 797
K +E ++ V N G E + + +P P P+ G++ +QW P
Sbjct: 29206 KNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPES 29265
Query: 798 DGGQPILGYILERKKKKSYRWMRLNFD-LIQELSHEARRMIEGVVYEMRVYAVNAIGMSR 856
DGG I Y++++++KKS RW R+N D ++ + + ++EG Y+ RV AVNA G S
Sbjct: 29266 DGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSE 29325
Query: 857 PSPAS------QPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCP 910
PS AS +P GPPS P V D + ++SL W P G + GY +E
Sbjct: 29326 PSEASNFISCREPSYTPGPPSAPR---VVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQE 29382
Query: 911 EGCSEWVAALQGLT-EHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQ 969
+ +W T +T V DL G + FRV A N+ G + + E ++
Sbjct: 29383 KDTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIE 29442
Query: 970 RPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTI 1029
P L+L L++T+ + G + L++ G+P P +TW+K+G LA + I + + ++
Sbjct: 29443 IPDLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAI-IDTTESYSL 29501
Query: 1030 LFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPP 1089
L + R +G Y + ++ + AT++++V D P P ++V + +V + W+ P
Sbjct: 29502 LIVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIP 29561
Query: 1090 QDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSD 1149
G + Y V+K + + TV +T + L+ G YYFRV +N+ G +
Sbjct: 29562 TIDGGAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGE 29621
Query: 1150 RAATTKEPVFIPRPGITYEPPNYKALDFSEAP---SFTQPLVN-RSVIAGYTAMLCCA 1203
T+ + P + P + +D +++ ++ +PL + S + GY C A
Sbjct: 29622 PCETSDAVLVSEVPLV---PAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKA 29676
Score = 188 bits (477), Expect = 3e-47
Identities = 139/490 (28%), Positives = 224/490 (45%), Gaps = 24/490 (4%)
Query: 700 DAPEDTGDSDEWVF--DKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPV 757
D PED G + + +K+ +T ++ V ++ R+ F V K+ E + V +N
Sbjct: 27679 DVPEDNGGGEITCYSIEKRETSQTNWKM-VCSSVARTTFKVPNLVKDAEYQFRVRAENRY 27737
Query: 758 GEDQVNLTVKVID-----VPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKK 812
G Q ++ ++ +P P P I NV D ++ W+ P YDGG + G+ +E+K+
Sbjct: 27738 GVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKE 27797
Query: 813 KKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQ---PFMPIGP 869
+ S W ++N I + A ++EG+ Y+ RVYA N+ G+S PS S+ P+ P
Sbjct: 27798 RNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDP 27857
Query: 870 PSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSI 929
P P ++ DV+ T++LKW PP R G + GYS+E +G WV
Sbjct: 27858 PGTPDYI---DVTRETITLKWNPPLRDGGSKIVGYSIEK-RQGNERWVRCNFTDVSECQY 27913
Query: 930 LVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTV-QEILQRPRLQLPRHLRQTIQKKVG 988
V L G R FR+ A N G +P + + + + ++ P ++ + K G
Sbjct: 27914 TVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSG 27973
Query: 989 EPVNLLIPFQGKPRPQVTWTKEGQPLAGE-EVSIRNSPTDTILFIRAARRVHSGTYQVTV 1047
E + + QG+P P+VTW K+G + + I + T LF+R A R H G Y V
Sbjct: 27974 ESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEA 28033
Query: 1048 RIENMEDKATLVLQVVDKPSP-PQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKAD 1106
+ + KA + ++V D P +R T+ G + L W P + G + Y ++K +
Sbjct: 28034 KNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRE 28093
Query: 1107 KKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGF-----SDRAATTKEPVFIP 1161
+ W + + +LI GN Y FRV + N G SD +
Sbjct: 28094 TSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPD 28153
Query: 1162 RPGITYEPPN 1171
PGI EP N
Sbjct: 28154 APGIP-EPSN 28162
Score = 185 bits (469), Expect = 3e-46
Identities = 224/932 (24%), Positives = 347/932 (37%), Gaps = 158/932 (16%)
Query: 374 QVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAA 433
+V + ++ E+ A+ KW +N + I SKYI TL I L D A
Sbjct: 12650 RVKEQQEVVFNCEVNTEGAKAKWFRNEEAI-FDSSKYIILQKDLVYTLRIRDAHLDDQAN 12708
Query: 434 YQCVVGGE-----KCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLK 488
Y + K + L V+E + I PL+D M + V F C+V+ +KW K
Sbjct: 12709 YNVSLTNHRGENVKSAANLIVEEEDLRIVEPLKDIETMEKKSVTFWCKVNRLNVTLKWTK 12768
Query: 489 DGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVY 548
+G E+ + YR K +H L I + D G Y + +++AEL++ E E
Sbjct: 12769 NGEEVPFDNRVSYRVDK--YKHMLTIKDCGFPDEGEYIVTAGQDKSVAELLIIEAPTEFV 12826
Query: 549 QSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTP 608
+ + D V D AVF C++S E W +NG+E+ + K G +H+L I D
Sbjct: 12827 EHLEDQTVTEFDDAVFSCQLSREKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDCRL 12886
Query: 609 ADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLR 668
DE +Y+ E A+L E+ ++ + PP+ L+ PG D + + NK +
Sbjct: 12887 DDECEYACGVEDRKSR--ARLFVEEIPVEII---RPPQDILEAPGA--DVVFLAELNKDK 12939
Query: 669 LDVPISGDPAPTVIWQK---AITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRV 725
++V W + + QG+K E + +C+ + R
Sbjct: 12940 VEVQ----------WLRNNMVVVQGDKHQMM------------SEGKIHRLQICDIKPR- 12976
Query: 726 RVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGE 785
D+G Y K+ ++ L AAPKI +
Sbjct: 12977 -------------------DQGEYRFIAKDKEARAKLELA----------AAPKIKTADQ 13007
Query: 786 DSCTVQWEPPAYDGGQPILGYI-LERKKKKSYRWMRLNFDLIQEL-----SHEARRMIEG 839
D D G+P+ + + K W + N L + + R++E
Sbjct: 13008 DLVV--------DVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKTIDTTAEQTSFRILEA 13059
Query: 840 VVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAG 899
+ Y + + I P +L V + D VSL W P G
Sbjct: 13060 KKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDGEVSLAWEEPLTDGGS 13119
Query: 900 GLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGA-RLLFRVRAHNMAGPGAPVTT 958
+ GY VE WV A E V L G LFRV A N G G PV T
Sbjct: 13120 KIIGYVVERRDIKRKTWVLATDR-AESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVET 13178
Query: 959 TEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKE----GQPL 1014
PV R + +P G P+N+ I + +TW G +
Sbjct: 13179 DNPVEA-----RSKYDVP-----------GPPLNVTITDVNRFGVSLTWEPPEYDGGAEI 13222
Query: 1015 AGEEVSIRNSPT---DTILFIRAARR-------VHSGTYQVTVRIENM-----EDKATLV 1059
+ +R+ + DT + +RA V Y VR +N AT
Sbjct: 13223 TNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPF 13282
Query: 1060 LQVVD---KPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVL 1116
++V D +PSPP +L +D +V L+W+PP G + + GY +++ ++ W
Sbjct: 13283 VKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWI--- 13339
Query: 1117 EHYRRTHCVVPELII-------GNGYYFRVFSQNMVGFSDRAAT----TKEPVFIPRPGI 1165
R +VPEL GN Y +RV ++N G SD + T + F+
Sbjct: 13340 ---RCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFV----- 13391
Query: 1166 TYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDA 1225
EP +D S +F L VI + G P+P +W L
Sbjct: 13392 --EP----TMDLS---AFKDGL---EVIVPNPITILVPSTGYPRPTATWCFGDKVLETGD 13439
Query: 1226 RFRMFSKQGVLTLEIRKPCPFDGGIYVCRATN 1257
R +M + L I D GIY + N
Sbjct: 13440 RVKMKTLSAYAELVISPSERSDKGIYTLKLEN 13471
Score = 184 bits (467), Expect = 5e-46
Identities = 128/483 (26%), Positives = 224/483 (46%), Gaps = 20/483 (4%)
Query: 702 PEDTGDSD--EWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVG- 758
PE G S ++ +K+ + +G V+TT + TV + V+ V +N +G
Sbjct: 14107 PEKDGGSPITNYIVEKRDV-RRKGWQTVDTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQ 14165
Query: 759 ------EDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKK 812
ED V L P P A + +V + ++WEPP DGG+PI Y++E+K+
Sbjct: 14166 SDYTEIEDSV-LAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKE 14224
Query: 813 KKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PIGP 869
+ RW++ + + +IEG + +V A N G+ PS ++ P P
Sbjct: 14225 RLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSP 14284
Query: 870 PSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSI 929
PS P L V D +++ W+PPE+ G + GY VE CP G +W+ +
Sbjct: 14285 PSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKF 14344
Query: 930 LVKD-LPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVG 988
V++ + + RVRA N G P +E V ++ +P + L H I+ G
Sbjct: 14345 KVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHDIIVIE---G 14401
Query: 989 EPVNLLIPFQGKPRPQVTWTKEGQPL-AGEEVSIRNSPTDTILFIRAARRVHSGTYQVTV 1047
E +++ +PF+ P P V+W K+G+ + A + ++++N L + + R +G Y +T+
Sbjct: 14402 EKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITL 14461
Query: 1048 RIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADK 1107
+ A++ ++V+ P P +D++ +D + L W+PP+ G T + Y +++ +
Sbjct: 14462 ENKLGSATASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREA 14521
Query: 1108 KTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITY 1167
+ V+ + V +LI Y+FRV + N VG K PV P
Sbjct: 14522 GRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVG-GGEYIELKNPVIAQDPKQPP 14580
Query: 1168 EPP 1170
+PP
Sbjct: 14581 DPP 14583
Score = 183 bits (465), Expect = 8e-46
Identities = 119/406 (29%), Positives = 184/406 (45%), Gaps = 15/406 (3%)
Query: 772 PDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSH 831
P P P ++++ +D VQW P DGG I+GY LE+K+K S W++LN IQ+
Sbjct: 24505 PGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKF 24564
Query: 832 EARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PIGPPSEPTHLAVEDVSDTTVSL 888
+ + EG+ YE +V A N +G+ +PS S+ F+ P PP P + ++ V+L
Sbjct: 24565 KTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAIV---ITRNNVTL 24621
Query: 889 KWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHN 948
KW+ P G + GY VE W+ A T V L R FRV A N
Sbjct: 24622 KWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGLVEDQRYEFRVIARN 24681
Query: 949 MAGP-GAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTW 1007
AG P ++ +T ++ + P L + I GE L +GKP P V W
Sbjct: 24682 AAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVW 24741
Query: 1008 TKEGQPL--AGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDK 1065
+K+G+ L + I+++ T L ++ R G Y + + + ++V+D+
Sbjct: 24742 SKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDR 24801
Query: 1066 PSPPQ-DLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHC 1124
P PP+ L+VT L W PP G + Y ++K + + W V + +
Sbjct: 24802 PGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLSWTQVSTEVQALNY 24861
Query: 1125 VVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPP 1170
V +L+ GN Y FRV + N G + PV P Y+PP
Sbjct: 24862 KVTKLLPGNEYIFRVMAVNKYGIGE--PLESGPVTACNP---YKPP 24902
Score = 183 bits (465), Expect = 8e-46
Identities = 149/599 (24%), Positives = 245/599 (40%), Gaps = 43/599 (7%)
Query: 577 WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKI 636
W K+G+ L +R+ VS V L+I + + D Y A +++ + + I
Sbjct: 25428 WRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSIT-----VPITI 25482
Query: 637 DFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPAR 696
+ R PP +R+D +S D T+ W G +
Sbjct: 25483 IVLDRPGPP-------------------GPIRID-EVSCDSI-TISWNPPEYDGGCQISN 25521
Query: 697 PAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNP 756
+ E T S W + + T ++ TT F V + + Y+
Sbjct: 25522 YIVEKKETT--STTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYS------ 25573
Query: 757 VGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSY 816
E + P P PK+ + + + V W+ P DGG ++GY LE K++ S
Sbjct: 25574 --ESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSI 25631
Query: 817 RWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHL 876
W + N LI + + + EG++YE RVYA N G+ + S + +P P P
Sbjct: 25632 LWSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQP 25691
Query: 877 AVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPT 936
V +++ +VSLKW P G + GY VE W+ + T V +L
Sbjct: 25692 EVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQETYFEVTELTE 25751
Query: 937 GARLLFRVRAHNMA-GPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLI 995
R FRV A N A P +T P+ V++ ++ PR+ + R I K GE + +
Sbjct: 25752 DQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINA 25811
Query: 996 PFQGKPRPQVTWTKEGQPLAGE-EVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMED 1054
G+P P ++W K+G + I ++ T+L ++ R +G Y +T++
Sbjct: 25812 DIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTR 25871
Query: 1055 KATLVLQVVDKPSPPQ-DLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWF 1113
+ +V+DKP PP L + +L W PQ+ G ++ Y V+K + + W
Sbjct: 25872 SVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQEDGGADIDYYIVEKRETSHLAWT 25931
Query: 1114 TVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDR----AATTKEPVFIPRPGITYE 1168
+ T C V +L+ GN Y FRV N G + A +P +P P + E
Sbjct: 25932 ICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLE 25990
Score = 182 bits (462), Expect = 2e-45
Identities = 114/380 (30%), Positives = 178/380 (46%), Gaps = 5/380 (1%)
Query: 771 VPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELS 830
+P P + +++N+ +DS TV W P DGG I+GYI+E++ + RW++ N I +L
Sbjct: 23818 LPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLR 23877
Query: 831 HEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PIGPPSEPTHLAVEDVSDTTVS 887
+ E YE RV A NA G+ PSPA+ + P+ P PT+ + D + +++
Sbjct: 23878 LRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHIVDTTKNSIT 23937
Query: 888 LKWRPPERVGAGGLDGYSVEYCPEGCSEW-VAALQGLTEHTSILVKDLPTGARLLFRVRA 946
L W P G + GY VE C EW + Q T + L RV A
Sbjct: 23938 LAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCA 23997
Query: 947 HNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVT 1006
N G G + V ++ L+ P L L LR+ I + G + IPF+G+P P++T
Sbjct: 23998 LNKVGLGEATSVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGSARIHIPFKGRPTPEIT 24057
Query: 1007 WTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKP 1066
W++E ++V I T L I R +G Y + + + A + ++V+D P
Sbjct: 24058 WSREEGEFT-DKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTP 24116
Query: 1067 SPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVV 1126
PPQ+L V + + L W+PP G ++ Y + K + + V +T V
Sbjct: 24117 GPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKV 24176
Query: 1127 PELIIGNGYYFRVFSQNMVG 1146
L G YYFRV ++N G
Sbjct: 24177 ENLTEGAIYYFRVMAENEFG 24196
Score = 180 bits (456), Expect = 9e-45
Identities = 116/381 (30%), Positives = 183/381 (48%), Gaps = 6/381 (1%)
Query: 772 PDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSH 831
P AP P++ +V ++ +++WE P +DGG I+GY +E+K++ + W++ N E ++
Sbjct: 28841 PSAPTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNY 28900
Query: 832 EARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWR 891
+ ++EG+ Y+ R YA+NA G+S+ S AS+P M P P V DV+ +TVSL W
Sbjct: 28901 KVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQNPVDAPGRPEVTDVTRSTVSLIWS 28960
Query: 892 PPERVGAGGLDGYSVEYCP---EGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHN 948
P G + GY +E P G W+ + V L G FRV A N
Sbjct: 28961 APAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKN 29020
Query: 949 MAGP-GAPVTTTEPVTVQEILQRPRLQLPRHLR-QTIQKKVGEPVNLLIPFQGKPRPQVT 1006
AG +T PVT ++ P+ +L L + + G + L GKP P++
Sbjct: 29021 AAGVISKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIRAGSDLVLDAAVGGKPEPKII 29080
Query: 1007 WTKEGQPL-AGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDK 1065
WTK + L E+VS++ + I+ R SG Y +TV+ + +++++V+D
Sbjct: 29081 WTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLDS 29140
Query: 1066 PSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCV 1125
P P L V+ L W PQ+ G E+ Y V++ + + W V V
Sbjct: 29141 PGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLSYV 29200
Query: 1126 VPELIIGNGYYFRVFSQNMVG 1146
V LI N Y FRV + N G
Sbjct: 29201 VTRLIKNNEYIFRVRAVNKYG 29221
Score = 173 bits (438), Expect = 1e-42
Identities = 193/761 (25%), Positives = 301/761 (39%), Gaps = 153/761 (20%)
Query: 3 EPGKKPVSAFSKKPRSVEVAAGSPAVFEAETERAG-VKVRWQRGGSDISASNKYGLATEG 61
EP K PV F + V V+ G + + ++++W + G +I S++ +
Sbjct: 8341 EPKKPPV--FDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFSFAS 8398
Query: 62 TRHTLTVREVGPADQGSYAV----IAGSSKVKFDLKVIEAEKAEPMLAPAPAPAEATGAP 117
L +R+V AD G Y +AGS K + + K +P +APA
Sbjct: 8399 GTAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTI----KDKPAVAPA---------- 8444
Query: 118 GEAPAPAAELGESAPSPKGSSSAALNGPTPGAPDDPIGLFVMRPQDGEVTVGGSITFSAR 177
+ AA++G FV PQ V + TF A+
Sbjct: 8445 -------------------TKKAAVDGRL---------FFVSEPQSIRVVEKTTATFIAK 8476
Query: 178 VAGASLLKPPVVKWFKGKWVDLSSKVGQHLQLHDSYDRASKVYLFELHITDAQPAFTGSY 237
V G + P VKW KGKW L+ G + +H D A +L I D +G Y
Sbjct: 8477 VGGDPI---PNVKWTKGKWRQLNQ--GGRVFIHQKGDEA------KLEIRDTTKTDSGLY 8525
Query: 238 RCEVSTKDKFDCSNFNLTVHEAMGTGDLDLLSAFRRTSLAGGGRRISDSHEDTGILDFSS 297
RC + SN NL V E ++ + G D +
Sbjct: 8526 RCVAFNEHGEIESNVNLQVDERK-----------KQEKIEG---------------DLRA 8559
Query: 298 LLKKRDSFRTPRDSKLEAPAEE-DVWEILRQAPPSEYERIAFQYGVTDLRGML------- 349
+LKK TP K EE D+ E+L+ P EYE+ A YG+TD RG+L
Sbjct: 8560 MLKK-----TPILKKGAGEEEEIDIMELLKNVDPKEYEKYARMYGITDFRGLLQAFELLK 8614
Query: 350 ------------KRLKGMRRDEKK----STAFQKKLEPAYQVSKGHKIRLTVELADHDA- 392
+ ++ RDEK+ + Q++L V+ I L D+DA
Sbjct: 8615 QSQEEETHRLEIEEIERSERDEKEFEELVSFIQQRLSQTEPVTLIKDIENQTVLKDNDAV 8674
Query: 393 ------------EVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGG 440
++ W K ++++ S K+ G + TL + C L D Y+ V G
Sbjct: 8675 FEIDIKINYPEIKLSWYKGTEKLEPS-DKFEISIDGDRHTLRVKNCQLKDQGNYRLVCGP 8733
Query: 441 EKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFK 500
S +L V EP R L+D + GQ C+ S + +W ++G L + +
Sbjct: 8734 HIASAKLTVIEP--AWERHLQDVTLKEGQTCTMTCQFSVPNVKSEWFRNGRILKPQG--R 8789
Query: 501 YRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAKD 560
++ + + + H L I + ED G Y + AEL ++ + ++ + I +++V
Sbjct: 8790 HKTEVEHKVHKLTIADVRAEDQGQYTCKYEDLETSAELRIEAEPIQFTKRIQNIVVSEHQ 8849
Query: 561 QAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFV--- 617
A F+CEVS ++ W K EL + + GR H +TI +VTP DE YS +
Sbjct: 8850 SATFECEVSFDDAIVTWYKGPTELTESQKYNFRNDGRCHYMTIHNVTPDDEGVYSVIARL 8909
Query: 618 -PEGFACNLSAKLHF--MEVKIDFVPRQEPPK--------IHLDCPGRIPDTIVVVAGNK 666
P G A +A+L+ E+K++ P P I P IP VV
Sbjct: 8910 EPRGEA-RSTAELYLTTKEIKLELKPPDIPDSRVPIPTMPIRAVPPEEIPP--VVAPPIP 8966
Query: 667 LRLDVPISGDPAP--TVIWQKAITQ-GNKAPARPAPDAPED 704
L L P P P + +KA+ + K A+P P +
Sbjct: 8967 LLLPTPEEKKPPPKRIEVTKKAVKKDAKKVVAKPKEMTPRE 9007
Score = 171 bits (432), Expect = 5e-42
Identities = 157/594 (26%), Positives = 238/594 (40%), Gaps = 72/594 (12%)
Query: 707 DSDEWVFDKKL-LCETEGRVRVETTKDRSIFTV-----EGAEKEDEGVYTVTVKNPVGED 760
D+D+WV K+ + +T RV+ T K + F V G K + + +K+P
Sbjct: 13925 DTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDP---- 13980
Query: 761 QVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMR 820
ID P P P + +VG+ S + W P +DGG I Y++E K + W+R
Sbjct: 13981 --------IDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVR 14032
Query: 821 LNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PIGPPSEPTHLA 877
+ + + H ++EG Y RV AVN G S PS S P + + PPS P L
Sbjct: 14033 VA-EGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLE 14091
Query: 878 VEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTG 937
V +++ T LKW PE+ G + Y VE W + + T V L G
Sbjct: 14092 VINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGW-QTVDTTVKDTKCTVTPLTEG 14150
Query: 938 ARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKV---------- 987
+ +FRV A N G + V ++ P + ++ V
Sbjct: 14151 SLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKND 14210
Query: 988 -GEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSP----TDTILFIRAARRVHSGT 1042
G P+ + + K R W K G+ AG + + R + T+ +RA G
Sbjct: 14211 GGRPIQRYV-IEKKERLGTRWVKAGKT-AGPDCNFRVTDVIEGTEVQFQVRAENEAGVGH 14268
Query: 1043 YQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTV 1102
I ++ED + PSPP DL VTDA ++A+ WKPP+ G + + GY V
Sbjct: 14269 PSEPTEILSIEDPTS-------PPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHV 14321
Query: 1103 QKADKKTMEWFTVLEH------YRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKE 1156
+ T +W V ++ VVP+ Y RV + N +G S E
Sbjct: 14322 EMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPD----KEYVLRVRAVNAIGVS-------E 14370
Query: 1157 PVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFK 1216
P I + +P +D T ++ VI G + R P P +SW K
Sbjct: 14371 PSEISENVVAKDPDCKPTIDLE-----THDII---VIEGEKLSIPVPFRAVPVPTVSWHK 14422
Query: 1217 NGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
+G ++ R M + LE+ K D GIY N G A ++V
Sbjct: 14423 DGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKV 14476
Score = 164 bits (414), Expect = 7e-40
Identities = 217/917 (23%), Positives = 362/917 (39%), Gaps = 124/917 (13%)
Query: 395 KWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCSTELFVKEPPV 454
KWLKNG EI+ S K + +L I D A Y V G + L+V+ +
Sbjct: 3000 KWLKNGVEIK-STDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHI 3058
Query: 455 LITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLII 514
+ ++D V+ +R FECEVSE V+W+KD EL + T + + +K+ H L+I
Sbjct: 3059 EFRKHIKDIKVLEKKRAMFECEVSEPDITVQWMKDDQEL--QITDRIKIQKEKYVHRLLI 3116
Query: 515 NEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDENVR 574
+ DAG Y + G + A+L V+ + + + ++ V K +AV + EV++++V
Sbjct: 3117 PSTRMSDAGKYTVVAGGNVSTAKLFVEGRDVRIRSIKKEVQVIEKQRAVVEFEVNEDDVD 3176
Query: 575 GVWLKNGKEL--VPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFM 632
W K+G E+ R K R+H++ I + +D +Y+FV +++
Sbjct: 3177 AHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVTL----- 3231
Query: 633 EVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNK 692
+V EPP++ + + V +G R ISG P P + W K
Sbjct: 3232 -----YVNAPEPPQVLQEL-----QPVTVQSGKPARFCAVISGRPQPKISWYK------- 3274
Query: 693 APARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVT 752
+E + C+ + ++ ++ +E A ED VYT
Sbjct: 3275 ----------------EEQLLSTGFKCKF-----LHDGQEYTLLLIE-AFPEDAAVYTCE 3312
Query: 753 VKNPVG--EDQVNLTVKVIDV--PDAPA---APKISNVGEDSCTVQWEPPAY----DGGQ 801
KN G +L+V+V +V PD P I +D+ T + +P + G
Sbjct: 3313 AKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTD 3372
Query: 802 PILGYILERKKKKSYRWMRLN--FDLIQELSHEARRMIEGVVYEMRVYAVNAI----GMS 855
+ + + KK K R+ R+ D Q EA EG + AV + +S
Sbjct: 3373 LKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLS 3432
Query: 856 RPSPAS----------QPFMPIGP----PSEPTHLAVEDVSDTTVSLKWRPPERVG--AG 899
+P S + M P EP +A+ ++ T ++ P R
Sbjct: 3433 LEAPESILHERIEQEIEMEMKAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKA 3492
Query: 900 GLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTT 959
G + Y + C S+++++L+ L V D + +A N G V+ T
Sbjct: 3493 GREIYESDKCSIRSSKYISSLEILRTQ----VVDCGE-----YTCKASNEYG---SVSCT 3540
Query: 960 EPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLA-GEE 1018
+TV E L P+ L VG+ + G P + W K+G L+
Sbjct: 3541 ATLTVTEAYPPTFLSRPKSLTTF----VGKAAKFICTVTGTPVIETIWQKDGAALSPSPN 3596
Query: 1019 VSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLR-VTDA 1077
I ++ IL + G Y + D L ++DKP ++L V A
Sbjct: 3597 WRISDAENKHILELSNLTIQDRGVYSCKASNKFGADICQAELIIIDKPHFIKELEPVQSA 3656
Query: 1078 WGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYF 1137
V LE + +D T W QK + + + + +P + + +
Sbjct: 3657 INKKVHLECQVDEDRKVTVTWSKDGQKLPPG--KDYKICFEDKIATLEIPLAKLKDSGTY 3714
Query: 1138 RVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNY-KALDFSEAPSFTQPLVNRSVIAGY 1196
+ N G S +AT EPP++ K +D PS+ ++ G
Sbjct: 3715 VCTASNEAGSSSCSATV----------TVREPPSFVKKVD----PSYL-------MLPGE 3753
Query: 1197 TAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRAT 1256
+A L C ++GSP +++WFKN +L E RM+ L+I D G Y C A
Sbjct: 3754 SARLHCKLKGSPVIQVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAV 3813
Query: 1257 NLQGEARCECRLEVRVP 1273
N G C + ++ P
Sbjct: 3814 NDVGSDSCSTEIVIKEP 3830
Score = 151 bits (381), Expect = 4e-36
Identities = 127/445 (28%), Positives = 198/445 (44%), Gaps = 36/445 (8%)
Query: 750 TVTVKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILE 809
T + +P+ V + + P AP P I+ V +DSC V W+PPA DGG I Y LE
Sbjct: 30803 TFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLE 30862
Query: 810 RKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPF----- 864
+++KK +W+ + + I+E + +IEG+ YE RV N G S S S+P
Sbjct: 30863 KREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSD 30922
Query: 865 MPIGPP---SEPTHLAVEDVSDTTVSLK-WRPPERVGAGGLDGYSVEYCPEGCSEWVAAL 920
+PI P E +L V S+ T+ K P+ + G E +G +
Sbjct: 30923 VPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQG--KEIIADGLKYRIQEF 30980
Query: 921 QGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLR 980
+G + +++ + +++VRA N G + E+ ++ LP+ L
Sbjct: 30981 KG--GYHQLIIASVTDDDATVYQVRATNQGG------SVSGTASLEVEVPAKIHLPKTLE 31032
Query: 981 --QTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGE----EVSIRNSPTDTILFIRA 1034
+ GE V++ IPF GKP P +TW K GQ L +V + S T +++F
Sbjct: 31033 GMGAVHALRGEVVSIKIPFSGKPDPVITWQK-GQDLIDNNGHYQVIVTRSFT-SLVFPNG 31090
Query: 1035 ARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGN 1094
R +G Y V + D+ T+ L V D P PP+ ++V+D +V L W P G
Sbjct: 31091 VERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGG 31150
Query: 1095 TELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATT 1154
+++ Y V+K W V R T V L Y FRV ++N G S
Sbjct: 31151 SKITNYIVEKCATTAERWLRV-GQARETRYTVINLFGKTSYQFRVIAENKFGLS------ 31203
Query: 1155 KEPVFIPRPGITYEPPNYKALDFSE 1179
+P P IT E +A+++ E
Sbjct: 31204 -KPSEPSEPTITKEDKT-RAMNYDE 31226
Score = 144 bits (364), Expect = 4e-34
Identities = 106/366 (28%), Positives = 162/366 (44%), Gaps = 48/366 (13%)
Query: 640 PRQEPPKI--------HLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGN 691
PR+ P I LD G ++ AG+ +++++P+ G P PTV W+K
Sbjct: 21048 PRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKK------ 21101
Query: 692 KAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTV 751
GD ++L +T+ RV ETT +I + + D G Y +
Sbjct: 21102 --------------GD--------QILKQTQ-RVNFETTATSTILNINECVRSDSGPYPL 21138
Query: 752 TVKNPVGEDQVNLTVKVIDVPDAPAAP-KISNVGEDSCTVQWEPPAYDGGQPILGYILER 810
T +N VGE +T++V D+P P P K V D T W+PP DGG PI Y++E
Sbjct: 21139 TARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEM 21198
Query: 811 KKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGM-----SRPSPASQPFM 865
++ S W+ L +I+ +++A R+ G+ Y+ RV A N G+ S A+ PF
Sbjct: 21199 RQTDSTTWVELATTVIRT-TYKATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFK 21257
Query: 866 PIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTE 925
GPP P V V+ ++++ W P G + GY VE W + L
Sbjct: 21258 VPGPPGTPQ---VTAVTKDSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVP 21314
Query: 926 HTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHL-RQTIQ 984
L G FRV A NMAG P +EP+ + + P +P ++ R T+
Sbjct: 21315 GNIFKSSGLTDGIAYEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHTVT 21374
Query: 985 KKVGEP 990
K +P
Sbjct: 21375 LKWAKP 21380
Score = 142 bits (357), Expect = 3e-33
Identities = 105/345 (30%), Positives = 153/345 (44%), Gaps = 43/345 (12%)
Query: 635 KIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNK-LRLDVPISGDPAPTVIWQKAITQGNKA 693
+I V R + LD G +PD + N RL +PI G PAP+V W+K
Sbjct: 19968 EITVVARDDVVAPDLDLKG-LPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKG------- 20019
Query: 694 PARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTV 753
ED T+ RV VE++ + V +K D G YT+T+
Sbjct: 20020 ---------EDP-------------LATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITL 20057
Query: 754 KNPVGEDQVNLTVKVIDVPDAPAAP-KISNVGEDSCTVQWEPPAYDGGQPILGYILERKK 812
KN G + +++KV+ P P P K V ++ T++W PP DGG I YILE++
Sbjct: 20058 KNVAGTKEGTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRD 20117
Query: 813 KKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGM-----SRPSPASQPF-MP 866
+ +W+ +Q+ + R+ EG+ Y RV A N G+ S P A PF +P
Sbjct: 20118 SVNNKWVTC-ASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVP 20176
Query: 867 IGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEH 926
PP P ++ DV +VSL W P++ G + GY +E+ W A +
Sbjct: 20177 DAPP--PPNIV--DVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRM 20232
Query: 927 TSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRP 971
V L G FRV A N+AG G P +EPV + + P
Sbjct: 20233 RDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPP 20277
Score = 140 bits (352), Expect = 1e-32
Identities = 120/428 (28%), Positives = 177/428 (41%), Gaps = 58/428 (13%)
Query: 375 VSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAY 434
V+ G EL+ D V+W G++++ S K + S G TLT+ L D
Sbjct: 12207 VTAGETATFDCELSYEDIPVEWYLKGKKLEPS-DKVVPRSEGKVHTLTLRDVKLEDAGEV 12265
Query: 435 QCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELT 494
Q K LFVKEPPV T+PLEDQ V G ECEVS E A+VKW K+G E+
Sbjct: 12266 QLTAKDFKTHANLFVKEPPVEFTKPLEDQTVEEGATAVLECEVSRENAKVKWFKNGTEIL 12325
Query: 495 REETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADL 554
+ + KY DG+ L+I++ ED Y + L V +E + + DL
Sbjct: 12326 KSK--KYEIVADGRVRKLVIHDCTPEDIKTYTCDAKDFKTSCNLNVVPPHVEFLRPLTDL 12383
Query: 555 MVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADY 614
V K+ A F+CE+S EN + W K+G E+ + + G V L I+ DEA+Y
Sbjct: 12384 QVREKEMARFECELSRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEY 12443
Query: 615 SFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPIS 674
S E S L +E + F I V + ++L +S
Sbjct: 12444 SC--EVRTARTSGMLTVLEEEAVFTKNLA--------------NIEVSETDTIKLVCEVS 12487
Query: 675 GDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRS 734
P VIW K GD + + ET GR + T +
Sbjct: 12488 -KPGAEVIWYK--------------------GDEE--------IIET-GRYEILTEGRKR 12517
Query: 735 IFTVEGAEKEDEGVYTVTVKNPVGEDQV---NLTVKVIDVP------DAPAAPKISNVGE 785
I ++ A ED G Y + + + +V L + I P + A + ++ +
Sbjct: 12518 ILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLEILEGEKAEFVCSISK 12577
Query: 786 DSCTVQWE 793
+S VQW+
Sbjct: 12578 ESFPVQWK 12585
Score = 137 bits (345), Expect = 7e-32
Identities = 127/511 (24%), Positives = 201/511 (39%), Gaps = 87/511 (17%)
Query: 643 EPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAP 702
+ P LD + D IVV AG L+ I G P P V+W K
Sbjct: 24703 DAPNASLD--PKYKDVIVVHAGETFVLEADIRGKPIPDVVWSK----------------- 24743
Query: 703 EDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQV 762
D K L ET R+ +++T ++ V+ + D G Y + + N G +
Sbjct: 24744 -----------DGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSI 24792
Query: 763 NLTVKVIDVPDAPAAP-KISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRL 821
+TVKV+D P P P K++ V + C + W PP DGG I YI+E+++ W ++
Sbjct: 24793 PITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLSWTQV 24852
Query: 822 NFDLIQELSHEARRMIEGVVYEMRVYAVNAIGM-----SRPSPASQPFMPIGPPSEPTHL 876
+ + +Q L+++ +++ G Y RV AVN G+ S P A P+ P GPPS P
Sbjct: 24853 STE-VQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACNPYKPPGPPSTP--- 24908
Query: 877 AVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPT 936
V ++ ++ + W P G ++GY +E + W + + V L
Sbjct: 24909 EVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLTDLRLRVTGLTE 24968
Query: 937 GARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIP 996
G FRV A N AG G P + + L P G P N +
Sbjct: 24969 GHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPP----------------GPPSNPKVT 25012
Query: 997 FQGKPRPQVTWTKE----GQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENM 1052
+ + W+K G P+ G V ++ + D + + VT EN
Sbjct: 25013 DTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENT 25072
Query: 1053 E--------------DKATLVLQVV--DKPSPPQ-----------DLRVTDAWGLNVALE 1085
E + ATL VV ++ PP+ LR + L V ++
Sbjct: 25073 EYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRASATLRLFVTIK 25132
Query: 1086 WKPPQDVGNTELWGYTVQKADKKTMEWFTVL 1116
+P +V + G +A + FT+L
Sbjct: 25133 GRPEPEVKWEKAEGILTDRAQIEVTSSFTML 25163
Score = 135 bits (340), Expect = 2e-31
Identities = 215/933 (23%), Positives = 349/933 (37%), Gaps = 118/933 (12%)
Query: 378 GHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCV 437
G + EL EV+WL+N + + G K+ S G L I D Y+ +
Sbjct: 12926 GADVVFLAELNKDKVEVQWLRNNMVV-VQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFI 12984
Query: 438 VGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSE-EGAQVKWLKDGVELTRE 496
++ +L + P + T +D +V VG+ + A+ +W K+ L+ +
Sbjct: 12985 AKDKEARAKLELAAAPKIKTAD-QDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTK 13043
Query: 497 ETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMV 556
++ I EA D G Y + AE + K ++V + +L V
Sbjct: 13044 T-----IDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEV 13098
Query: 557 GAKDQAVFKCEVSDENVRGVW---LKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEAD 613
E D V W L +G + ++ I R + D + E
Sbjct: 13099 ---------TETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAESCEFT 13149
Query: 614 YSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPI 673
+ + +G + F + V EP + D P V A +K DVP
Sbjct: 13150 VTGLQKG-----GVEYLFRVSARNRVGTGEP--VETDNP--------VEARSKY--DVP- 13191
Query: 674 SGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSD--EWVFDKK----LLCETEGRVRV 727
G P I T N+ + PE G ++ +V + + + +T VR
Sbjct: 13192 -GPPLNVTI-----TDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRA 13245
Query: 728 ETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLT---VKVIDVPDAPAAP---KIS 781
E VEG E + V +N +G + + VKV D + P+ P S
Sbjct: 13246 EDLSATVTDVVEGQEYS----FRVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSS 13301
Query: 782 NVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVV 841
+ + S ++WEPP DGG PILGYI+ER ++ W+R N L+ EL+++ + +G
Sbjct: 13302 DQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNK 13361
Query: 842 YEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGA-GG 900
Y RV A N G+S PS P EPT D+S L+ P +
Sbjct: 13362 YLYRVSAENKAGVSDPSEILGPLTADDAFVEPTM----DLSAFKDGLEVIVPNPITILVP 13417
Query: 901 LDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTE 960
GY P + W + L + +K L A L+ + G
Sbjct: 13418 STGY-----PRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENR 13472
Query: 961 PVTVQ-----EILQRPRLQLPRHLR-------------QTIQKKVGEPVNLLIPFQGKPR 1002
T+ ++ RP P+ L+ + G P+ + + +
Sbjct: 13473 VKTISGEIDVNVIARP--SAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYV-VEKREV 13529
Query: 1003 PQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIE--NMEDKATLVL 1060
+ TWTK + E ++ + + R G + E NM AT+
Sbjct: 13530 SRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATV-- 13587
Query: 1061 QVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYR 1120
P PP++++ D ++ L W PP++ G + + GY V++ + + +W E
Sbjct: 13588 -----PDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGEPVA 13642
Query: 1121 RTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEA 1180
T V L G Y +RV + N G S + T+E +A+D EA
Sbjct: 13643 ETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEE---------------IQAVDTQEA 13687
Query: 1181 PSF---TQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLT 1237
P + L +V AG L V G P+PKI+W K + L +D R + + T
Sbjct: 13688 PEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKST 13747
Query: 1238 LEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
+ I D G Y+ A N+ G A + V
Sbjct: 13748 VTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNV 13780
Score = 134 bits (338), Expect = 4e-31
Identities = 121/458 (26%), Positives = 200/458 (43%), Gaps = 38/458 (8%)
Query: 708 SDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVK 767
+D+WV K ++ TT ++TV G + E + + +N VG + + +
Sbjct: 30373 TDKWVRHNK--------TQITTT----MYTVTGLVPDAEYQFRIIAQNDVGLSETSPASE 30420
Query: 768 VI------DVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRL 821
+ D P P +I ++ +DS T+QWE P DGG+ ILGY +E ++ W +
Sbjct: 30421 PVVCKDPFDKPSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKS 30480
Query: 822 NFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDV 881
N + I++ ++E YE RV+A N G+SRP + E + E +
Sbjct: 30481 NKERIKDKQFTIGGLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPGIRKE-M 30539
Query: 882 SDTTVSLKWRPPERVGAGGLDGYSVEYCPEG-----CSEWVAALQGLTEHTSILVKDLPT 936
D T L G +++ G ++ + G T +++ ++
Sbjct: 30540 KDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQED 30599
Query: 937 GARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIP 996
++ A N G V T+ + +Q P+ L++ VG + L +
Sbjct: 30600 EG--VYTCIATNEVGE---VETSSKLLLQAT---PQFHPGYPLKEKYYGAVGSTLRLHVM 30651
Query: 997 FQGKPRPQVTWTKEGQPLA--GEEVSIRNSPTDTILFIR-AARRVHSGTYQVTVRIENME 1053
+ G+P P +TW GQ L E ++I N+ T L ++ R+ H+G Y+V +
Sbjct: 30652 YIGRPVPAMTWF-HGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGT 30710
Query: 1054 DKATLVLQVVDKPSPPQDLRVTDAWGLNVA-LEWKPPQDVGNTELWGYTVQKAD-KKTME 1111
A L +++ DKP P V +A N A + WKPP D G + + Y V+K + K+ E
Sbjct: 30711 VDAILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAE 30770
Query: 1112 WFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSD 1149
W V T C + L GYYFRV +QN G SD
Sbjct: 30771 WQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFGISD 30808
Score = 134 bits (337), Expect = 6e-31
Identities = 115/412 (27%), Positives = 167/412 (40%), Gaps = 57/412 (13%)
Query: 654 RIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVF 713
++ + V AG+ +RL+ + G P P V W K DA + T
Sbjct: 18206 KLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKD------------KDATDLTRSP----- 18248
Query: 714 DKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPD 773
RV+++T D S F++ A++ D G Y VT N G TV V+D P
Sbjct: 18249 ----------RVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPG 18298
Query: 774 APAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEA 833
KI +V D CTV W+PP DGG I YILE+ + K W + ++
Sbjct: 18299 PVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTP-GTTV 18357
Query: 834 RRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PIGPPSEPTHLAVEDVSDTTVSLKW 890
R+IEG Y RV A N IG P+ S+P + P P V VS +++ W
Sbjct: 18358 TRLIEGNEYIFRVRAENKIGTGPPT-ESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVW 18416
Query: 891 RPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMA 950
PPE G + GY +E + + WV + + V++L FRV+A N
Sbjct: 18417 NPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEI 18476
Query: 951 GPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKE 1010
G G P + PV ++ ++ P G P N + K + W K
Sbjct: 18477 GIGEPSLPSRPVVAKDPIEPP----------------GPPTNFRVVDTTKHSITLGWGKP 18520
Query: 1011 ----GQPLAGEEVSIR-----NSPTDTILFIRAARRVHSGTYQVTVRIENME 1053
G P+ G V +R SP + AA ++ + VT EN E
Sbjct: 18521 VYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQE 18572
Score = 132 bits (333), Expect = 2e-30
Identities = 101/340 (29%), Positives = 154/340 (45%), Gaps = 19/340 (5%)
Query: 649 LDCPGRIPDT-IVVVAGNKLRLDVPISGDPAPTVIWQKA--ITQGNKAPARPAPDAPEDT 705
+D P I T + V G+++ LD ISG P PT+ W K + + R AP
Sbjct: 14678 IDAPKVILRTSLEVKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRK 14737
Query: 706 GDSDEWVFDKKLLCETEGRVRVETTKD-RSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNL 764
G+ E ++ + R+ ++ +K S V + + D G+Y + V+N G +
Sbjct: 14738 GEVQE---EEPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPC 14794
Query: 765 TVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILER--KKKKSYRWMRLN 822
TV V+D P P ++ + S +WEPP DGG I+ Y LE+ K K W+ +
Sbjct: 14795 TVSVLDTPGPPINFVFEDIRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWIVVT 14854
Query: 823 FDLIQELSHEARRMIEGVVYEMRVYAVNAIG-----MSRPSPASQPFMPIGPPSEPTHLA 877
++ + ++IEG Y RV A N G +S+P A PF GPP P
Sbjct: 14855 -STLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKPLVAKDPF---GPPDAPDKPI 14910
Query: 878 VEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTG 937
VEDV+ ++ +KW P+ G+ L GY +E + W + L V L G
Sbjct: 14911 VEDVTSNSMLVKWNEPKDNGSPIL-GYWLEKREVNSTHWSRVNKSLLNALKANVDGLLEG 14969
Query: 938 ARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPR 977
+FRV A N AGPG ++P T + + P +PR
Sbjct: 14970 LTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIPR 15009
Score = 132 bits (331), Expect = 3e-30
Identities = 116/487 (23%), Positives = 193/487 (39%), Gaps = 56/487 (11%)
Query: 547 VYQSIADLMVGAKDQAVFKCEVSDENVRGV-WLKNGKELVPDSRIKVSHIGRVHKLTIDD 605
+ + + D+ + A C++ + + W + GKEL+ + K+S GR H LT+
Sbjct: 30535 IRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMT 30594
Query: 606 VTPADEADYSFVP--EGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVA 663
DE Y+ + E S+KL Q P+ H P + +
Sbjct: 30595 EEQEDEGVYTCIATNEVGEVETSSKLLL----------QATPQFHPGYP--LKEKYYGAV 30642
Query: 664 GNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEG 723
G+ LRL V G P P + W F + L +
Sbjct: 30643 GSTLRLHVMYIGRPVPAMTW-----------------------------FHGQKLLQNSE 30673
Query: 724 RVRVETTKDRSIFTVEGAEKEDE-GVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAP-KIS 781
+ +E T+ + ++ +++ G Y V + N G L V++ D PD P P I
Sbjct: 30674 NITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIE 30733
Query: 782 NVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVV 841
+ ++S + W+PPA DGG I Y++E+ + K +L I + + E
Sbjct: 30734 ALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAG 30793
Query: 842 YEMRVYAVNAIGMSRPSPAS------QPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPER 895
Y RV A N G+S P S PF G P +PT AV D+ V + W+PP
Sbjct: 30794 YYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAV--TKDSCV-VAWKPPAS 30850
Query: 896 VGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAP 955
G + Y +E + ++W++ T VK+L G FRV+ N+ G
Sbjct: 30851 DGGAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEW 30910
Query: 956 VTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLA 1015
+EP+T + + LR + + L+ G P+P V W ++G+ +
Sbjct: 30911 SEISEPITPKSDVPIQAPHFKEELR-NLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEII 30969
Query: 1016 GEEVSIR 1022
+ + R
Sbjct: 30970 ADGLKYR 30976
Score = 131 bits (329), Expect = 5e-30
Identities = 95/310 (30%), Positives = 133/310 (42%), Gaps = 39/310 (12%)
Query: 657 DTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKK 716
+T V+AG L++DVP G P P V W K D
Sbjct: 22155 NTFTVLAGEDLKVDVPFIGRPTPAVTWHK----------------------------DNV 22186
Query: 717 LLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPA 776
L +T RV E+T++ S+ T++ A +ED G Y V + N GE L V V+D P P
Sbjct: 22187 PLKQTT-RVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPPT 22245
Query: 777 AP-KISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARR 835
P K+ V DS T+ W PP YDGG I YI+E++ + W ++ + + +A R
Sbjct: 22246 GPVKMDEVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTWQIVSAT-VARTTIKACR 22304
Query: 836 MIEGVVYEMRVYAVNAIGMS-----RPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKW 890
+ G Y+ R+ A N G S P+ A PF GPP P V S ++ ++W
Sbjct: 22305 LKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPV---VTLSSRDSMEVQW 22361
Query: 891 RPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMA 950
P G + GY +E WV + T L G FRV A N+
Sbjct: 22362 NEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIV 22421
Query: 951 GPGAPVTTTE 960
G G P +E
Sbjct: 22422 GIGKPSKVSE 22431
Score = 130 bits (328), Expect = 6e-30
Identities = 94/317 (29%), Positives = 141/317 (44%), Gaps = 37/317 (11%)
Query: 643 EPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAP 702
+PP+I +D + DTIVV AG ++D I G P PT+ W K
Sbjct: 22539 DPPRISMD--PKYKDTIVVHAGESFKVDADIYGKPIPTIQWIK----------------- 22579
Query: 703 EDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQV 762
GD + R+ +++T + +V+ A + D G Y + KN GE V
Sbjct: 22580 ---GDQE---------LSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSV 22627
Query: 763 NLTVKVIDVPDAPAAP-KISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRL 821
+ VKV+D P P P IS V + CT+ W+PP DGG I+ YI+ER++ W +
Sbjct: 22628 TVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVV 22687
Query: 822 NFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGP---PSEPTHLAV 878
+ + +Q LS + +++EG Y R+ AVN G+ P S+P + P P P V
Sbjct: 22688 DAN-VQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPL-ESEPVVAKNPFVVPDAPKAPEV 22745
Query: 879 EDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGA 938
V+ ++ + W P G + GY +E + W + L + V L
Sbjct: 22746 TTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENH 22805
Query: 939 RLLFRVRAHNMAGPGAP 955
FRV A N AG P
Sbjct: 22806 DYEFRVSAENAAGLSEP 22822
Score = 128 bits (321), Expect = 4e-29
Identities = 99/421 (23%), Positives = 172/421 (40%), Gaps = 64/421 (15%)
Query: 644 PPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPE 703
PP+I L + + V AG + LD + G P PTV W+K
Sbjct: 19292 PPRIDLSVA--MKSLLTVKAGTNVCLDATVFGKPMPTVSWKK------------------ 19331
Query: 704 DTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVE--GAEKEDEGVYTVTVKNPVGEDQ 761
D LL EG ++ R++ T+E ++D G YT+T +N G
Sbjct: 19332 ----------DGTLLKPAEG---IKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKS 19378
Query: 762 VNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRL 821
+ +KV+D P PA+ KI+ + D + WEPP DGG I YI+++++ W ++
Sbjct: 19379 ATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNWAQV 19438
Query: 822 NFDLIQELSHEARRMIEGVVYEMRVYAVNAIGM-----SRPSPASQPFMPIGPPSEPTHL 876
+ + S ++IEG Y+ R+ A N G+ + P+ A P+ P G P
Sbjct: 19439 S-ATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPP--- 19494
Query: 877 AVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPT 936
+ +++ +++ W+PP G + GY +E W + ++ L
Sbjct: 19495 VISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQE 19554
Query: 937 GARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIP 996
G FRV A N AGPG P ++ ++ P G P +
Sbjct: 19555 GTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPP----------------GPPAFPKVY 19598
Query: 997 FQGKPRPQVTWTKE----GQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENM 1052
+ ++W K G P+ G V ++ + +D + + + ++VT +E+
Sbjct: 19599 DTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMEDT 19658
Query: 1053 E 1053
+
Sbjct: 19659 Q 19659
Score = 127 bits (320), Expect = 5e-29
Identities = 107/389 (27%), Positives = 163/389 (41%), Gaps = 50/389 (12%)
Query: 365 FQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTIS 424
F K LE V +G L E++ +A+VKW KNG EI + KY + G R L I
Sbjct: 12287 FTKPLEDQ-TVEEGATAVLECEVSRENAKVKWFKNGTEI-LKSKKYEIVADGRVRKLVIH 12344
Query: 425 QCSLADDAAYQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQV 484
C+ D Y C K S L V P V RPL D V + FECE+S E A+V
Sbjct: 12345 DCTPEDIKTYTCDAKDFKTSCNLNVVPPHVEFLRPLTDLQVREKEMARFECELSRENAKV 12404
Query: 485 KWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKK 544
KW KDG E+ + + KY G L+IN+ +L+D Y+ + L V E++
Sbjct: 12405 KWFKDGAEIKKGK--KYDIISKGAVRILVINKCLLDDEAEYSCEVRTARTSGMLTVLEEE 12462
Query: 545 LEVYQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTID 604
+++A++ V D CEVS +W K +E++ R ++ GR L I
Sbjct: 12463 AVFTKNLANIEVSETDTIKLVCEVSKPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQ 12522
Query: 605 DVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAG 664
+ D +Y+ + K+H E+ +F+ + P + ++ G
Sbjct: 12523 NAHLEDAGNYNCRLPSSRTDGKVKVH--ELAAEFISK--------------PQNLEILEG 12566
Query: 665 NKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGR 724
K IS + P V W++ D ++GD + + D G+
Sbjct: 12567 EKAEFVCSISKESFP-VQWKR-------------DDKTLESGDKYDVIAD--------GK 12604
Query: 725 VRVETTKDRSIFTVEGAEKEDEGVYTVTV 753
RV KD ++ +D G Y V V
Sbjct: 12605 KRVLVVKDATL--------QDMGTYVVMV 12625
Score = 127 bits (318), Expect = 9e-29
Identities = 91/356 (25%), Positives = 152/356 (42%), Gaps = 39/356 (10%)
Query: 643 EPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAP 702
E P+I +D R DTIVV AG RL+ + G P PT+ W +
Sbjct: 23621 ELPRISMDPKFR--DTIVVNAGETFRLEADVHGKPLPTIEWLRG---------------- 23662
Query: 703 EDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQV 762
DK++ E R ++ T +++ V+ A + D G Y + N G
Sbjct: 23663 -----------DKEI--EESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSF 23709
Query: 763 NLTVKVIDVPDAPAAP-KISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRL 821
+ VKV+D P P P +++ V + C++ W PP DGG I Y++E+++ W +
Sbjct: 23710 PVNVKVLDRPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISHYVVEKRETSRLAWTVV 23769
Query: 822 NFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM--PIGPPSEPTHLAVE 879
+++ S + +++EG Y R+ AVN G+ P ++ M P P P L V
Sbjct: 23770 ASEVVTN-SLKVTKLLEGNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVT 23828
Query: 880 DVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGAR 939
+++ ++++ W P+ G + GY VE W+ + + V L
Sbjct: 23829 NIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHE 23888
Query: 940 LLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKV----GEPV 991
FRV A N AG G P T + + +P H+ T + + G+P+
Sbjct: 23889 YEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPI 23944
Score = 127 bits (318), Expect = 9e-29
Identities = 97/336 (28%), Positives = 144/336 (42%), Gaps = 38/336 (11%)
Query: 640 PRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAP 699
P+ EP D G I AG+ +DVPISG PAP V W+
Sbjct: 28641 PQIEPTA---DLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWK--------------- 28682
Query: 700 DAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGE 759
++ L ET+ RV + TTKDR+ TV+ + + D G Y +T++N G
Sbjct: 28683 -------------LEEMRLKETD-RVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGV 28728
Query: 760 DQVNLTVKVIDVPDAPAAP-KISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRW 818
++TV VI P P ++S+V +SC + W P GG I YI+E+++ + W
Sbjct: 28729 KTFSVTVVVIGRPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAW 28788
Query: 819 MRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PIGPPSEPTH 875
+N ++ + + + + Y RV + N G+S+P S P + P PPS PT
Sbjct: 28789 QLVNSS-VKRTQIKVTHLTKYMEYSFRVSSENRFGVSKPLE-SAPIIAEHPFVPPSAPTR 28846
Query: 876 LAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLP 935
V VS +S++W P G + GY VE WV + + V L
Sbjct: 28847 PEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLV 28906
Query: 936 TGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRP 971
G FR A N AG + P+ Q + P
Sbjct: 28907 EGLEYQFRTYALNAAGVSKASEASRPIMAQNPVDAP 28942
Score = 124 bits (312), Expect = 4e-28
Identities = 103/421 (24%), Positives = 167/421 (39%), Gaps = 57/421 (13%)
Query: 643 EPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAP 702
E PKI +D + DT+++ AG RL+ +SG P PT+ W K
Sbjct: 21457 EAPKIKVDV--KFKDTVILKAGEAFRLEADVSGRPPPTMEWSK----------------- 21497
Query: 703 EDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQV 762
D K L E ++ ++ + + + + D G YT+T NP G +
Sbjct: 21498 -----------DGKEL-EGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGGFAKH 21545
Query: 763 NLTVKVIDVPDAPAAP-KISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRL 821
VKV+D P P P ++ V + C + W PP DGG I YI+++++ W +
Sbjct: 21546 IFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNV 21605
Query: 822 NFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PIGPPSEPTHLAV 878
+ +Q + ++++G Y RV AVN G+ P S+P + P GPP P + V
Sbjct: 21606 ASE-VQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPL-ESEPVLAVNPYGPPDPPKNPEV 21663
Query: 879 EDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGA 938
++ ++ + W P+ G + Y VE + W+ + V L G
Sbjct: 21664 TTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGH 21723
Query: 939 RLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQ 998
FR+ A N AG AP T+ + + +P G P N +
Sbjct: 21724 EYEFRIMAENAAGISAPSPTSPFYKACDTVFKP----------------GPPGNPRVLDT 21767
Query: 999 GKPRPQVTWTKE----GQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMED 1054
+ + W K G + G V I D + + + +Y +T EN E
Sbjct: 21768 SRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKATSYTITGLTENQEY 21827
Query: 1055 K 1055
K
Sbjct: 21828 K 21828
Score = 123 bits (309), Expect = 1e-27
Identities = 133/548 (24%), Positives = 211/548 (38%), Gaps = 60/548 (10%)
Query: 739 EGAEKEDEGVYTVTVKNPVGEDQVNLTVKVID------VPDAPAAPKISNVGEDSCTVQW 792
EG E E Y V +N G + T +I +P P+ PKI + G+ + T+ W
Sbjct: 26049 EGCEYE----YRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAW 26104
Query: 793 EPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAI 852
P +DGG PI GY +E KK W + + ++ + + G Y RV +VN +
Sbjct: 26105 VKPLFDGGAPITGYTVEYKKSDDTDW-KTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKV 26163
Query: 853 GMSRPSPASQPFMPIGPPSEPTHLAVEDVSDT-----------TVSLKWRPPERV--GAG 899
G S PS +S P + EP ++ T TV + RP V
Sbjct: 26164 GASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKP 26223
Query: 900 GLDGYSVEYCPEGCSEWVAALQGLTEHTS----ILVKDLPTGARLLFRVRAHNMAGPGAP 955
D + Y S ++ + S + ++++ + A L V+ + GP
Sbjct: 26224 DTDLRTRAYVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGPPTN 26283
Query: 956 VTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLA 1015
+T + +L +P + G PV + + + W
Sbjct: 26284 ITVQDVTKESAVLS---WDVP-------ENDGGAPVKNY-HIEKREASKKAWVSVTNNCN 26332
Query: 1016 GEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVT 1075
+ N I + R + G V + E E +++ +KPSPP+ L VT
Sbjct: 26333 RLSYKVTNLQEGAIYYFRVSGENEFG---VGIPAETKEG-----VKITEKPSPPEKLGVT 26384
Query: 1076 DAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGY 1135
+V+L W P+ G + + Y V+ +K W + TH VV L + Y
Sbjct: 26385 SISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQKNWVKCAVA-KSTHHVVSGLRENSEY 26443
Query: 1136 YFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAG 1195
+FRVF++N G SD PV I EPP +D PS T V AG
Sbjct: 26444 FFRVFAENQAGLSDPRELLL-PVLIKEQ---LEPPE---IDMKNFPSHTV-----YVRAG 26491
Query: 1196 YTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRA 1255
+ + G P PK++ ++G+ L RF LT+ +++ D G Y A
Sbjct: 26492 SNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITA 26551
Query: 1256 TNLQGEAR 1263
N G +
Sbjct: 26552 ANSSGTTK 26559
Score = 121 bits (304), Expect = 4e-27
Identities = 84/310 (27%), Positives = 131/310 (42%), Gaps = 39/310 (12%)
Query: 657 DTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKK 716
+T + AG L++++P+ G P P + W K D +
Sbjct: 24319 NTYSIQAGEDLKIEIPVIGRPRPNISWVK----------------------------DGE 24350
Query: 717 LLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPA 776
L +T RV VE T ++ ++ K+D G YTVT N G NL+V V++ P P
Sbjct: 24351 PLKQTT-RVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGPPV 24409
Query: 777 AP-KISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARR 835
P + V D + WEPPAY GG I YI+E++ + W ++ + + + +
Sbjct: 24410 GPVRFDEVSADFVVISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVSAT-VARTTIKITK 24468
Query: 836 MIEGVVYEMRVYAVNAIGMSRPSPASQ-----PFMPIGPPSEPTHLAVEDVSDTTVSLKW 890
+ G Y+ R++A N G S P + PF GPP P V +S + ++W
Sbjct: 24469 LKTGTEYQFRIFAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPF---VTSISKDQMLVQW 24525
Query: 891 RPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMA 950
P G + GY +E + WV + + T L G F+V A N+
Sbjct: 24526 HEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIV 24585
Query: 951 GPGAPVTTTE 960
G G P +E
Sbjct: 24586 GIGKPSKVSE 24595
Score = 121 bits (304), Expect = 4e-27
Identities = 89/349 (25%), Positives = 156/349 (44%), Gaps = 15/349 (4%)
Query: 738 VEGAEKEDEGVYTVTVKNPVG-----EDQVNLTVKV-IDVPDAPA-APKISNVGEDSCTV 790
V+G ++ E + V+ +N G + + +T K ++ P+ P+ P++ +V + S ++
Sbjct: 30289 VKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSL 30348
Query: 791 QWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVN 850
W P DGG + GY +ERK+ + +W+R N I + ++ Y+ R+ A N
Sbjct: 30349 SWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQFRIIAQN 30408
Query: 851 AIGMSRPSPASQPFM---PIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVE 907
+G+S SPAS+P + P PS+P L + +S +V+L+W PE G + GY VE
Sbjct: 30409 DVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVE 30468
Query: 908 YCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEI 967
Y G S W + + + + L FRV A N G P T ++++
Sbjct: 30469 YRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYEFRVFAENETGLSRPRRTA--MSIKTK 30526
Query: 968 LQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPL-AGEEVSIRNSPT 1026
L R + + K+GE L G+P P + W + G+ L + + +
Sbjct: 30527 LTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGR 30586
Query: 1027 DTILFIRAARRVHSGTYQ--VTVRIENMEDKATLVLQVVDKPSPPQDLR 1073
L + + G Y T + +E + L+LQ + P L+
Sbjct: 30587 THTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLK 30635
Score = 121 bits (303), Expect = 5e-27
Identities = 99/388 (25%), Positives = 160/388 (41%), Gaps = 45/388 (11%)
Query: 480 EGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELI 539
E Q KW+ E RE F + +G + + L ++ + +++
Sbjct: 30865 EKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSDVP 30924
Query: 540 VQEKKLEVYQSIADLMVGAKDQAVFKCEVSDENVRGV-WLKNGKELVPDS-RIKVSHI-G 596
+Q + + + +L V + A C+V+ V W + GKE++ D + ++ G
Sbjct: 30925 IQAPHFK--EELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKG 30982
Query: 597 RVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIP 656
H+L I VT D Y ++S +EV++ P KIHL
Sbjct: 30983 GYHQLIIASVTDDDATVYQVRATNQGGSVSGTAS-LEVEV-------PAKIHLPKTLEGM 31034
Query: 657 DTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKK 716
+ + G + + +P SG P P + WQK +
Sbjct: 31035 GAVHALRGEVVSIKIPFSGKPDPVITWQKG-----------------------------Q 31065
Query: 717 LLCETEGRVRVETTKD-RSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAP 775
L + G +V T+ S+ G E++D G Y V KN G DQ + + V DVPD P
Sbjct: 31066 DLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPP 31125
Query: 776 AAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARR 835
K+S+V DS + W PA DGG I YI+E+ + RW+R+ +E +
Sbjct: 31126 RGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVG--QARETRYTVIN 31183
Query: 836 MIEGVVYEMRVYAVNAIGMSRPSPASQP 863
+ Y+ RV A N G+S+PS S+P
Sbjct: 31184 LFGKTSYQFRVIAENKFGLSKPSEPSEP 31211
Score = 120 bits (301), Expect = 8e-27
Identities = 94/330 (28%), Positives = 139/330 (42%), Gaps = 42/330 (12%)
Query: 644 PPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPE 703
PPK LD D + + AG+ L LD + G P P +IW K
Sbjct: 29043 PPKAELDARLH-GDLVTIRAGSDLVLDAAVGGKPEPKIIWTKG----------------- 29084
Query: 704 DTGDSDEWVFDKKL-LCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQV 762
DK+L LCE +V ++ T R+ ++ ++ D G YT+TVKN G V
Sbjct: 29085 ----------DKELDLCE---KVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAV 29131
Query: 763 NLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLN 822
++ VKV+D P +S V ++ CT+ W P DGG I YI+ER++ W+ +
Sbjct: 29132 SVMVKVLDSPGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLNWVIVE 29191
Query: 823 FDLIQELSHEARRMIEGVVYEMRVYAVNAIG-----MSRPSPASQPFMPIGPPSEPTHLA 877
+ LS+ R+I+ Y RV AVN G S P A F PP P +
Sbjct: 29192 GE-CPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVG 29250
Query: 878 VEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEH-TSILVKDLPT 936
+ ++W PE G + Y V+ + W + + T + V L
Sbjct: 29251 ---TGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLME 29307
Query: 937 GARLLFRVRAHNMAGPGAPVTTTEPVTVQE 966
G FRV A N AG P + ++ +E
Sbjct: 29308 GCDYQFRVTAVNAAGNSEPSEASNFISCRE 29337
Score = 120 bits (300), Expect = 1e-26
Identities = 207/954 (21%), Positives = 349/954 (36%), Gaps = 149/954 (15%)
Query: 360 KKSTAFQKKLEPAYQVSKGHKIRLTVELADHDA-EVKWLKNGQEIQMSGSKYIFESIGAK 418
++ +F KK++P+Y + G RL +L +V W KN +E+ S + ++ + ++
Sbjct: 3734 REPPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTWFKNNKELSESNTVRMY-FVNSE 3792
Query: 419 RTLTISQCSLADDAAYQCV----VGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFE 474
L I+ + D +Y C VG + CSTE+ +KEPP I + LE ++ G +
Sbjct: 3793 AILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKEPPSFI-KTLEPADIVRGTNALLQ 3851
Query: 475 CEVSEEGA-QVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQ 533
CEVS G ++ W KD ++ + KYR L I D G Y C +
Sbjct: 3852 CEVSGTGPFEISWFKDKKQIRSSK--KYRLFSQKSLVCLEIFSFNSADVGEYE-CVVANE 3908
Query: 534 -----ALAELIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDS 588
+A +++E V + + +G + + E + W+K + + D
Sbjct: 3909 VGKCGCMATHLLKEPPTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEVIREDG 3968
Query: 589 RIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIH 648
+IK+S V L I DV + Y+ + E A + + + + +EP KI
Sbjct: 3969 KIKMSFSNGVAVLIIPDVQISFGGKYTCLAENEAGS--------QTSVGELIVKEPAKII 4020
Query: 649 LDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDS 708
+ I V AG+ L+ ++G P W K D
Sbjct: 4021 -----ERAELIQVTAGDPATLEYTVAGTPELKPKWYK---------------------DG 4054
Query: 709 DEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKV 768
V KK R+ + + AE D G YT + N VG T V
Sbjct: 4055 RPLVASKK--------YRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTV 4106
Query: 769 IDVPDAPAAPK----ISNVGEDSCTVQWEPPAYDGGQPI-LGYILERKKKKSYRWMRLNF 823
+D AP K + +V +C + + G P+ + + + K+ + R+ F
Sbjct: 4107 LDRDIAPFFTKPLRNVDSVVNGTCRLDCK---IAGSLPMRVSWFKDGKEIAASDRYRIAF 4163
Query: 824 DLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDV-- 881
+ S E R+ A N++G S A + PPS T +DV
Sbjct: 4164 -VEGTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGA---LIVQEPPSFVTKPGSKDVLP 4219
Query: 882 -----------SDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSIL 930
T ++++W + G Y + E E L
Sbjct: 4220 GSAVCLKSTFQGSTPLTIRWFKGNKELVSGGSCYITKEALESSLE------------LYL 4267
Query: 931 VKDLPTGARLLFRVRAHNMAGP---GAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKV 987
VK +G + + N+AG A + EP T E L+ +L K
Sbjct: 4268 VKTSDSGT---YTCKVSNVAGGVECSANLFVKEPATFVEKLEPSQL-----------LKK 4313
Query: 988 GEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNS--PTDTILFIRAARRVHSGTYQV 1045
G+ L G P ++TW + + E R S + +L + SG Y
Sbjct: 4314 GDATQLACKVTGTPPIKITWFANDREIK-ESSKHRMSFVESTAVLRLTDVGIEDSGEYMC 4372
Query: 1046 TVRIENMEDKATLVLQVVDKP------SPPQDLRVTDAWGLNVALEWKPPQDVGNTELWG 1099
+ E D + ++ V + P P + L+ D L + PP ++ T
Sbjct: 4373 EAQNEAGSDHCSSIVIVKESPYFTKEFKPIEVLKEYDVM-LLAEVAGTPPFEI--TWFKD 4429
Query: 1100 YTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVF 1159
T+ ++ +K + + +H + Y RV ++ T +EP
Sbjct: 4430 NTILRSGRKYKTF--IQDHLVSLQILKFVAADAGEYQCRVTNEVGSSICSARVTLREP-- 4485
Query: 1160 IPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGL 1219
PSF + + + S + G TA ++GS ++W K+
Sbjct: 4486 ---------------------PSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSD 4524
Query: 1220 DLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVRVP 1273
++ ED RM + V +L + G YVC+A N G RC L V+ P
Sbjct: 4525 EITEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKEP 4578
Score = 119 bits (298), Expect = 2e-26
Identities = 80/274 (29%), Positives = 134/274 (48%), Gaps = 6/274 (2%)
Query: 365 FQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTIS 424
F KL+ V K I L E++ DA VKW K+G+EI+ S + I ++ G KR L +
Sbjct: 12020 FTGKLQDYTGVEKDEVI-LQCEISKADAPVKWFKDGKEIKPSKNAVI-KADGKKRMLILK 12077
Query: 425 QCSLADDAAYQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQV 484
+ +D Y C G +K S +L +++ + + RPL VM + FE E+SE+
Sbjct: 12078 KALKSDIGQYTCDCGTDKTSGKLDIEDREIKLVRPLHSVEVMETETARFETEISEDDIHA 12137
Query: 485 KWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKK 544
W G L +T K++G+ H L+++ L+ G + ++ A L V+ +
Sbjct: 12138 NWKLKGEALL--QTPDCEIKEEGKIHSLVLHNCRLDQTGGVDFQAANVKSSAHLRVKPRV 12195
Query: 545 LEVYQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTID 604
+ + + + D+ V A + A F CE+S E++ W GK+L P ++ G+VH LT+
Sbjct: 12196 IGLLRPLKDVTVTAGETATFDCELSYEDIPVEWYLKGKKLEPSDKVVPRSEGKVHTLTLR 12255
Query: 605 DVTPADEADYSFVPEGFACNLSAKLHFMEVKIDF 638
DV D + + F + A L E ++F
Sbjct: 12256 DVKLEDAGEVQLTAKDFKTH--ANLFVKEPPVEF 12287
Score = 119 bits (297), Expect = 2e-26
Identities = 81/306 (26%), Positives = 131/306 (42%), Gaps = 39/306 (12%)
Query: 661 VVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCE 720
V G L+++VPISG P PT+ W K D L +
Sbjct: 23241 VQVGQDLKIEVPISGRPKPTITWTK----------------------------DGLPLKQ 23272
Query: 721 TEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAP-K 779
T R+ V + D + +++ K+D G Y +TV N VG+ ++ + +D PD P P K
Sbjct: 23273 TT-RINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVK 23331
Query: 780 ISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEG 839
+V +S T+ W PP Y GG I YI++++ + W ++ + + + ++ G
Sbjct: 23332 FDDVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSAT-VARTTLKVTKLKTG 23390
Query: 840 VVYEMRVYAVNAIGMS-----RPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPE 894
Y+ R++A N G S P A P+ GPP P A+ S ++ ++W P
Sbjct: 23391 TEYQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAI---SKDSMVIQWHEPV 23447
Query: 895 RVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGA 954
G + GY +E W + + T ++L G FRV A N+ G G
Sbjct: 23448 NNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGK 23507
Query: 955 PVTTTE 960
+E
Sbjct: 23508 ASKNSE 23513
Score = 118 bits (295), Expect = 4e-26
Identities = 86/275 (31%), Positives = 130/275 (47%), Gaps = 7/275 (2%)
Query: 365 FQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTIS 424
F KL V K +I L E++ D VKW K+G+EI S KY ++ G +R L I
Sbjct: 11665 FTVKLHDKTAVEKD-EITLKCEVSK-DVPVKWFKDGEEIVPS-PKYSIKADGLRRILKIK 11721
Query: 425 QCSLADDAAYQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQV 484
+ L D Y C G +K + V+ + + +PL V VG+ FE E+SE
Sbjct: 11722 KADLKDKGEYVCDCGTDKTKANVTVEARLIKVEKPLYGVEVFVGETAHFEIELSEPDVHG 11781
Query: 485 KWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKK 544
+W G LT + +DG++H LI++ L G + + ++ A L V+E
Sbjct: 11782 QWKLKGQPLTASPDCE--IIEDGKKHILILHNCQLGMTGEVSFQAANAKSAANLKVKELP 11839
Query: 545 LEVYQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTID 604
L ++D+ V KD+A F+CEVS E WLK +E+ D R ++ G H + I
Sbjct: 11840 LIFITPLSDVKVFEKDEAKFECEVSREPKTFRWLKGTQEITGDDRFELIKDGTKHSMVIK 11899
Query: 605 DVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFV 639
DEA Y F E + S KL +++ F+
Sbjct: 11900 SAAFEDEAKYMFEAED--KHTSGKLIIEGIRLKFL 11932
Score = 117 bits (294), Expect = 5e-26
Identities = 82/248 (33%), Positives = 119/248 (47%), Gaps = 8/248 (3%)
Query: 386 ELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCST 445
E++ + WLKNG EI+MS K+ G L I S D A Y V G ++ S
Sbjct: 2904 EVSHFNVPSMWLKNGVEIEMS-EKFKIVVQGKLHQLIIMNTSTEDSAEYTFVCGNDQVSA 2962
Query: 446 ELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKK 505
L V P++IT L+D + FE V+ EG KWLK+GVE+ + + R KK
Sbjct: 2963 TLTVT--PIMITSMLKDINAEEKDTITFEVTVNYEGISYKWLKNGVEIKSTDKCQMRTKK 3020
Query: 506 DGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFK 565
H L I DA Y + A L V+ + +E + I D+ V K +A+F+
Sbjct: 3021 --LTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIEFRKHIKDIKVLEKKRAMFE 3078
Query: 566 CEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNL 625
CEVS+ ++ W+K+ +EL RIK+ VH+L I +D Y+ V G N+
Sbjct: 3079 CEVSEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVAGG---NV 3135
Query: 626 SAKLHFME 633
S F+E
Sbjct: 3136 STAKLFVE 3143
Score = 117 bits (294), Expect = 5e-26
Identities = 76/266 (28%), Positives = 117/266 (43%), Gaps = 7/266 (2%)
Query: 370 EPAY--QVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCS 427
+P Y +V G +EL++ D +W GQ + S I E G K L + C
Sbjct: 11755 KPLYGVEVFVGETAHFEIELSEPDVHGQWKLKGQPLTASPDCEIIED-GKKHILILHNCQ 11813
Query: 428 LADDAAYQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWL 487
L K + L VKE P++ PL D V +FECEVS E +WL
Sbjct: 11814 LGMTGEVSFQAANAKSAANLKVKELPLIFITPLSDVKVFEKDEAKFECEVSREPKTFRWL 11873
Query: 488 KDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEV 547
K E+T ++ F+ KDG +H ++I A ED Y +LI++ +L+
Sbjct: 11874 KGTQEITGDDRFE--LIKDGTKHSMVIKSAAFEDEAKYMFEAEDKHTSGKLIIEGIRLKF 11931
Query: 548 YQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVT 607
+ D+ K+ AVF E+S +N+R W KN + L + + G+ H +T D++
Sbjct: 11932 LTPLKDVTAKEKESAVFTVELSHDNIRVKWFKNDQRLHTTRSVSMQDEGKTHSITFKDLS 11991
Query: 608 PADEADYSFVPEGFACNLSAKLHFME 633
D + E + AKL +E
Sbjct: 11992 IDDTSQIRV--EAMGMSSEAKLTVLE 12015
Score = 116 bits (291), Expect = 1e-25
Identities = 216/935 (23%), Positives = 344/935 (36%), Gaps = 128/935 (13%)
Query: 365 FQKKLEPAYQVSKGHKIRLTVELADH-DAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTI 423
F KKLEP+ V + R ++ + +V W K+ EIQ S SK+ + + L +
Sbjct: 7307 FIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQES-SKFRMSFVDSVAVLEM 7365
Query: 424 SQCSLADDAAYQC----VVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSE 479
S+ D Y C G ST L VKEPP+ +P + + G V ECE+
Sbjct: 7366 HNLSVEDSGDYTCEAHNAAGSASSSTSLKVKEPPIFRKKPHPIE-TLKGADVHLECELQG 7424
Query: 480 EGA-QVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHY---ALCTSGGQAL 535
V W KD EL + +K + H++ +A D G Y A G
Sbjct: 7425 TPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAA--DIGEYQCKATNDVGSDTC 7482
Query: 536 AELIVQEKKLEVYQSIADL--MVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDS-RIKV 592
I + + ++D+ +VG + Q E + E + VW K+ E+V +S I +
Sbjct: 7483 VGSIALKAPPRFVKKLSDISTVVGKEVQLQTTIEGA-EPISVVWFKDKGEIVRESDNIWI 7541
Query: 593 SHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCP 652
S+ + L V PA+ Y+ C + E + EP I
Sbjct: 7542 SYSENIATLQFSRVEPANAGKYT-------CQIKNDAGMQEC-FATLSVLEPATIV---- 7589
Query: 653 GRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWV 712
P++I V G+ L+ ++G P + W K D E T D+
Sbjct: 7590 -EKPESIKVTTGDTCTLECTVAGTPELSTKWFK--------------DGKELTSDN---- 7630
Query: 713 FDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVID-- 770
+ ++ S + D GVY+ V+NPVG+D +++V D
Sbjct: 7631 -----------KYKISFFNKVSGLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRT 7679
Query: 771 VPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPI-LGYILERKKKKSYRWMRLNFDLIQEL 829
VP + G +V E Y G PI + + E + S R + L
Sbjct: 7680 VPPSFTRKLKETNGLSGSSVVMECKVY-GSPPISVSWFHEGNEISSGR--KYQTTLTDNT 7736
Query: 830 SHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPS---EPTHLAVEDVSDTTV 886
M+E + Y A M+ S P PPS +P + V ++ T
Sbjct: 7737 CALTVNMLEES--DSGDYTCIATNMAGSDECSAPLTVREPPSFVQKPDPMDVLTGTNVTF 7794
Query: 887 S--LKWRPPERVG--AGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLF 942
+ +K PP V G + + C + VA L+ + D+ T +
Sbjct: 7795 TSIVKGTPPFSVSWFKGSSELVPGDRCNVSLEDSVAELE---------LFDVDTSQSGEY 7845
Query: 943 RVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPR 1002
N AG + T ++ P + R +I+K G+P+ L F G P
Sbjct: 7846 TCIVSNEAGKAS-------CTTHLYIKAPAKFVKRLNDYSIEK--GKPLILEGTFTGTPP 7896
Query: 1003 PQVTWTKEGQPLA-GEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQ 1061
VTW K G + + +I + IL I ++ +G Y + + +D + +
Sbjct: 7897 ISVTWKKNGINVTPSQRCNITTTEKSAILEIPSSTVEDAGQYNCYIENASGKDSCSAQIL 7956
Query: 1062 VVDKPS-----PPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVL 1116
+++ P P + V D+ L L G E+ G + K D K T
Sbjct: 7957 ILEPPYFVKQLEPVKVSVGDSASLQCQL-------AGTPEI-GVSWYKGDTKLRPTTTYK 8008
Query: 1117 EHYRRTHC--VVPELIIGNGYYFRVFSQNMVG-FSDRAATTKEPVFIPRPGITYEPPNYK 1173
H+R V ++ I + + ++N VG S T + +P
Sbjct: 8009 MHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQKLP------------ 8056
Query: 1174 ALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQ 1233
PSF++ L + G + CA+ GS +SW+K+G L + +
Sbjct: 8057 -------PSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGKPLKDSPNVQTSFLD 8109
Query: 1234 GVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRL 1268
TL I K G Y C ATN G A RL
Sbjct: 8110 NTATLNIFKTDRSLAGQYSCTATNPIGSASSSARL 8144
Score = 115 bits (289), Expect = 2e-25
Identities = 84/310 (27%), Positives = 138/310 (44%), Gaps = 12/310 (3%)
Query: 360 KKSTAFQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKR 419
K+ F ++L+ K E ++ +VKW K+G E+ G KY S
Sbjct: 2171 KQLITFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVH-EGDKYRMHSDRKVH 2229
Query: 420 TLTISQCSLADDAAYQCVVGGE---KCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECE 476
L+I +D Y CV+ + K + +L V+ V + L+D V E EC
Sbjct: 2230 FLSILTIDTSDAEDYSCVLVEDENVKTTAKLIVEGAVVEFVKELQDIEVPESYSGELECI 2289
Query: 477 VSEEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALA 536
VS E + KW + VEL + KY R +L + + ED G Y+ G +
Sbjct: 2290 VSPENIEGKWYHNDVEL--KSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGKKTTC 2347
Query: 537 ELIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIG 596
+L ++ + + + Q ++D V D + +VS E+V GVW+K+G+E+ P R+ +
Sbjct: 2348 KLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHIVIDK 2407
Query: 597 RVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQ-----EPPKIHLDC 651
+ H L I+D+T D +YSF + S ++ V + P + E K L+C
Sbjct: 2408 QSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVDV-ITPLKDVNVIEGTKAVLEC 2466
Query: 652 PGRIPDTIVV 661
+PD V
Sbjct: 2467 KVSVPDVTSV 2476
Score = 114 bits (285), Expect = 6e-25
Identities = 99/408 (24%), Positives = 161/408 (39%), Gaps = 59/408 (14%)
Query: 649 LDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDS 708
+D P + + AG ++L ISG PAPT+ W K
Sbjct: 26872 IDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKD---------------------- 26909
Query: 709 DEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKV 768
DK+L +T V VE T D + ++ A++ + G Y + ++N +G + V++
Sbjct: 26910 -----DKEL--QTNALVCVENTTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQI 26962
Query: 769 IDVPDAPAAP-KISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQ 827
+D P P P + V + T+ W PPA DGG I YI+E+++ W ++ + ++
Sbjct: 26963 LDKPGPPGGPIEFKTVTAEKITLLWRPPADDGGAKITHYIVEKRETSRVVWSMVS-EHLE 27021
Query: 828 ELSHEARRMIEGVVYEMRVYAVNAIGMSRPSP-----ASQPFMPIGPPSEPTHLAVEDVS 882
E ++I+G Y RV AVN G+ P A F+ GPP P V ++
Sbjct: 27022 ECIITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIP---EVTKIT 27078
Query: 883 DTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLF 942
++++ W P G + GY +E + W L+ T V L + +
Sbjct: 27079 KNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQY 27138
Query: 943 RVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPR 1002
RV A N AG G +E + + P G P + I K
Sbjct: 27139 RVCAVNAAGQGPFSEPSEFYKAADPIDPP----------------GPPAKIRIADSTKSS 27182
Query: 1003 PQVTWTKE----GQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVT 1046
+ W+K G + G V IR + + V + Y V+
Sbjct: 27183 ITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVS 27230
Score = 113 bits (283), Expect = 1e-24
Identities = 256/1163 (22%), Positives = 416/1163 (35%), Gaps = 177/1163 (15%)
Query: 157 FVMRPQDGEVTVGGSITFSARVAGASLLKPPVVKWFKGKWVDLSSKVGQHLQLHDSYDRA 216
FV P+ EV G ++TF++ + G K V WF+G + G ++ D
Sbjct: 5895 FVKEPEPLEVLPGKNVTFTSVIRGTPPFK---VNWFRGARELVK---GDRCNIYFE-DTV 5947
Query: 217 SKVYLFELHITDAQPAFTGSYRCEVSTKDKFDCSNFNLTVHEAMGTGDLDLLSAFRRTSL 276
+++ LF + I+ + G Y C VS L V E L S+
Sbjct: 5948 AELELFNIDISQS-----GEYTCVVSNNAGQASCTTRLFVKEPAA-----FLKRLSDHSV 5997
Query: 277 AGGGRRISDSHEDTGILDFSSLLKKRDSFRTPRDSKLEAPAEED--VWEILRQAPPSEYE 334
G I +S TG L S KK D F K E + EIL +
Sbjct: 5998 EPGKSIILESTY-TGTLPISVTWKK-DGFNITTSEKCNIVTTEKTCILEILNST-----K 6050
Query: 335 RIAFQYGVTDLRGMLKRLKGMRRDEKKSTAFQKKLEPAYQVSKGHKIRLTVELADH-DAE 393
R A QY + + G + F +LEP + + G + L ++A +
Sbjct: 6051 RDAGQYSCEIENEAGRDVCGALVSTLEPPYFVTELEPL-EAAVGDSVSLQCQVAGTPEIT 6109
Query: 394 VKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCV----VGGEKCSTELFV 449
V W K +++ + +Y TL ++ ++ D Y C +G T +
Sbjct: 6110 VSWYKGDTKLRPT-PEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASSKTVFRI 6168
Query: 450 KEP--PVLITRPLEDQLVMVGQRVEFECEVSEEGA-QVKWLKDGVELTREETFKYRFKKD 506
+E P R L+D VG V C ++ QV W +DGV L +E + F +
Sbjct: 6169 QERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDDENLQTSFVDN 6228
Query: 507 GQRHHLIINEAMLEDAGHYALCTSG----GQALAELIVQEKKLEVYQSIADLMVG--AKD 560
L I + L +G Y+ S + A L +E K + I + + A +
Sbjct: 6229 VAT--LKILQTDLSHSGQYSCSASNPLGTASSSARLTAREPKKSPFFDIKPVSIDVIAGE 6286
Query: 561 QAVFKCEVSD-ENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPE 619
A F+C V+ + +R W K+ KE+ P ++ +G L I V D Y+
Sbjct: 6287 SADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQAT 6346
Query: 620 GFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAP 679
++ + ++ + +EPPK ++ + V G ++L+ ISG P
Sbjct: 6347 N---DVGKDMCSAQLSV-----KEPPKF----VKKLEASKVAKQGESIQLECKISGSPEI 6394
Query: 680 TVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVE 739
V W + D+ + W ++ + ++ T+
Sbjct: 6395 KVSWFR-----------------NDSELHESWKYNMSFI------------NSVALLTIN 6425
Query: 740 GAEKEDEGVYTVTVKNPVGEDQVN--LTVKVIDVPDAPAAPKISNVGED---SCTVQWEP 794
A ED G Y N VG+ + LTVK V +P + G D C + P
Sbjct: 6426 EASAEDSGDYICEAHNGVGDASCSTALTVKAPPVFTQKPSPVGALKGSDVILQCEISGTP 6485
Query: 795 PAYDGGQPILGYILERKK---KKSYRWMRLNFDL-IQELSHEARRMIEGVVYEMRVYAVN 850
P + ++ +RK+ K ++ +FD + L+ EA V E A N
Sbjct: 6486 PFE------VVWVKDRKQVRNSKKFKITSKHFDTSLHILNLEA-----SDVGEYHCKATN 6534
Query: 851 AIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCP 910
+G S S F EP V+ +SDT+ + R G SV +
Sbjct: 6535 EVG-SDTCSCSVKF------KEPPRF-VKKLSDTSTLIGDAVELRAIVEGFQPISVVWLK 6586
Query: 911 ---EGCSEWVAALQGLTEHTSILVKDLPTGARL-LFRVRAHNMAGP---GAPVTTTEPVT 963
E E ++ + L P + + + N AG A +T EP
Sbjct: 6587 DRGEVIRESENTRISFIDNIATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVLEPA- 6645
Query: 964 VQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGE---EVS 1020
I+++P + + G P L G P W K+G+ L+ + ++
Sbjct: 6646 --RIIEKP---------EPMTVTTGNPFALECVVTGTPELSAKWFKDGRELSADSKHHIT 6694
Query: 1021 IRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLR----VTD 1076
N L I A G Y V+ + T+ + V D+ PP +R V
Sbjct: 6695 FINKVAS--LKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVSDRIVPPSFIRKLKDVNA 6752
Query: 1077 AWGLNVALEWKPPQDVGNTELW---GYTVQKADKKTMEWFTVLEHYRRTHCVVPELII-- 1131
G +V LE + + W G + K + C + ++
Sbjct: 6753 ILGASVVLECRVSGSAPISVGWFQDGNEIVSGPK-------CQSSFSENVCTLNLSLLEP 6805
Query: 1132 -GNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNR 1190
G Y V + N+ G + +A L E PSF Q +
Sbjct: 6806 SDTGIYTCV-AANVAGSDECSA---------------------VLTVQEPPSFEQTPDSV 6843
Query: 1191 SVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGI 1250
V+ G + +RG+P K+ WFK +L + + V LE+ + P + G
Sbjct: 6844 EVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVPGESCNISLEDFVTELELFEVQPLESGD 6903
Query: 1251 YVCRATNLQGEARCECRLEVRVP 1273
Y C TN G A C L V+ P
Sbjct: 6904 YSCLVTNDAGSASCTTHLFVKEP 6926
Score = 112 bits (281), Expect = 2e-24
Identities = 106/428 (24%), Positives = 172/428 (40%), Gaps = 58/428 (13%)
Query: 867 IGPPSEPTH-LAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTE 925
IG P+ P L +D+ +V + WRPP G + GY +E + W +
Sbjct: 30225 IGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYT-IDSRVR 30283
Query: 926 HTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQK 985
TS++VK L FRV A N G P+ + EPVT + L P + P + + +
Sbjct: 30284 GTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPP--EPPSNPPEVLDV 30341
Query: 986 KVGEPVNLLIPFQGKPRPQVTWTKE----GQPLAGEEVSIRNSPTDTILFIRAAR-RVHS 1040
K ++W++ G + G + + + TD ++R + ++ +
Sbjct: 30342 T-------------KSSVSLSWSRPKDDGGSRVTGYYIERKETSTDK--WVRHNKTQITT 30386
Query: 1041 GTYQVTVRIENMEDKATLVLQ-------------------VVDKPSPPQDLRVTDAWGLN 1081
Y VT + + E + ++ Q DKPS P +L + +
Sbjct: 30387 TMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKDS 30446
Query: 1082 VALEWKPPQDVGNTELWGYTVQKADKKTMEWF-TVLEHYRRTHCVVPELIIGNGYYFRVF 1140
V L+W+ P+ G E+ GY V+ W + E + + L+ Y FRVF
Sbjct: 30447 VTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYEFRVF 30506
Query: 1141 SQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAML 1200
++N G S RP T K L EAP + + + + G A L
Sbjct: 30507 AENETGLS-------------RPRRTAMSIKTK-LTSGEAPGIRKEMKDVTTKLGEAAQL 30552
Query: 1201 CCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQG 1260
C + G P P I W++ G +L + +++M S TL + D G+Y C ATN G
Sbjct: 30553 SCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVG 30612
Query: 1261 EARCECRL 1268
E +L
Sbjct: 30613 EVETSSKL 30620
Score = 112 bits (280), Expect = 2e-24
Identities = 127/527 (24%), Positives = 203/527 (38%), Gaps = 79/527 (14%)
Query: 769 IDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFD-LIQ 827
I P P PK+ + ++ + W P DGG PILGY++E +K + +W R+N D LI+
Sbjct: 17801 IKPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKDELIR 17860
Query: 828 ELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMP---IGPPSEPTHLAVEDVSDT 884
+ + +IEG Y R+ A N +G P ++ + + PP + DV
Sbjct: 17861 QCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRDVITV 17920
Query: 885 TVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSI-LVKDLPTGARLLFR 943
V R RV PE W + L + L++DLP R+ +
Sbjct: 17921 RVGQTIRILARVKGR----------PEPDITWTKEGKVLVREKRVDLIQDLP---RVELQ 17967
Query: 944 VRAHNMAGPGAPVTTTEPVT-------VQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIP 996
++ A G + + + + + +L RP G NL +
Sbjct: 17968 IKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRP----------------GPCQNLKVT 18011
Query: 997 FQGKPRPQVTWTKE----GQPLAGEEVSIRNS--------PTDTILFIRAARRVHSGTYQ 1044
K ++W G + V R +D + A + + Y
Sbjct: 18012 NVTKENCTISWENPLDNGGSEITNFIVEYRKPNQKGWSIVASDVTKRLIKANLLANNEYY 18071
Query: 1045 VTVRIEN-------MEDKAT-LVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTE 1096
V EN +E K L + +D+P P++L + D V L+W+ P G +
Sbjct: 18072 FRVCAENKVGVGPTIETKTPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSP 18131
Query: 1097 LWGYTVQKADKKTMEWFTVLE-HYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTK 1155
Y V++ K + +W V + + TH +V + Y FRV ++N G SD T +
Sbjct: 18132 NLSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVENQIYEFRVQTKNEGGESDWVKTEE 18191
Query: 1156 EPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWF 1215
+ E LD + T V AG T L VRG P P+++W
Sbjct: 18192 V--------VVKEDLQKPVLDLKLSGVLT-------VKAGDTIRLEAGVRGKPFPEVAWT 18236
Query: 1216 --KNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQG 1260
K+ DL R ++ ++ + K DGG YV ATN G
Sbjct: 18237 KDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAG 18283
Score = 110 bits (274), Expect = 1e-23
Identities = 148/625 (23%), Positives = 238/625 (38%), Gaps = 79/625 (12%)
Query: 684 QKAITQGNKAPARPAPDAPEDTGDS-DEWVFDKKLLCETEGRVRVETTKD--------RS 734
Q +T+ K A + P D G ++ +K+ ET + TKD R
Sbjct: 17017 QPIVTEVTKDSALVTWNKPHDGGKPITNYILEKR---ETMSKRWARVTKDPIHPYTKFRV 17073
Query: 735 IFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDV------PDAPAAPKISNVGEDSC 788
+EG + E + V+ +N +G + K + P P P+ + +S
Sbjct: 17074 PDLLEGCQYE----FRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSV 17129
Query: 789 TVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNF--DLIQELSHEARRMIEGVVYEMRV 846
+ W+PP +DGG ILGYI+E +K W R N + E ++ + +G Y+ RV
Sbjct: 17130 DLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRV 17189
Query: 847 YAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSV 906
AVNA G S P+ +P + + EP L ++ +K R+ A +
Sbjct: 17190 LAVNAAGESDPAHVPEPVL-VKDRLEPPELILDANMAREQHIKVGDTLRLSA------II 17242
Query: 907 EYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQE 966
+ P W + T + P G++L R AH G + +T P +
Sbjct: 17243 KGVPFPKVTW--KKEDRDAPTKARIDVTPVGSKLEIRNAAHEDGGIYS-LTVENPAGSKT 17299
Query: 967 ILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKE----GQPLAGEEVSIR 1022
+ ++ + K G P +L + K +TW + G + V R
Sbjct: 17300 V----------SVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERR 17349
Query: 1023 N------SPTDTILFIRA--ARRVHSGT-YQVTVRIENMEDKATLV--------LQVVDK 1065
+ SP ++ A+ ++ G Y V EN + V L +
Sbjct: 17350 DVASAQWSPLSATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHP 17409
Query: 1066 PSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCV 1125
P PP+DL D V+L W P G + + GY V+ ++ T +W + CV
Sbjct: 17410 PGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIK-FKTVTNLECV 17468
Query: 1126 VPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQ 1185
V L G Y FRV ++N+VG T P+ + PP+ + LD +
Sbjct: 17469 VTGLQQGKTYRFRVKAENIVGLG--LPDTTIPIECQEKLV---PPSVE-LDV----KLIE 17518
Query: 1186 PLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCP 1245
LV V AG T +RG P P W +G ++ D + + + L I+
Sbjct: 17519 GLV---VKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLR 17575
Query: 1246 FDGGIYVCRATNLQGEARCECRLEV 1270
D G Y +N G L V
Sbjct: 17576 RDTGEYQITVSNAAGSKTVAVHLTV 17600
Score = 109 bits (272), Expect = 2e-23
Identities = 185/803 (23%), Positives = 284/803 (35%), Gaps = 153/803 (19%)
Query: 542 EKKLEVYQSIADLMVGAKDQAVFK-CEVSDENVRGVWLKN--GKELVPDSRIKVSHIGRV 598
+K+L++ + ++ G + AV K C+ SD + +KN G + V + G
Sbjct: 29085 DKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLDSPGPC 29144
Query: 599 HKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIH-LDCPGRIPD 657
KLT+ VT A +L + E+ V R+E +++ + G P
Sbjct: 29145 GKLTVSRVTQEKCT--------LAWSLPQEDGGAEITHYIVERRETSRLNWVIVEGECPT 29196
Query: 658 TIVVV--------------AGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPE 703
VV A NK VP+ +P I N P PE
Sbjct: 29197 LSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEP---------IVARNSFTIPSPPGIPE 29247
Query: 704 DTGDSDEWVFDKKLLCETEGRVRVET----------------TKDRSIFT--------VE 739
+ G E + + E++G + KD ++ +E
Sbjct: 29248 EVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLME 29307
Query: 740 GAEKEDEGVYTVTVKNPVGEDQVNLTVKVID------VPDAPAAPKISNVGEDSCTVQWE 793
G + + + VT N G + + I P P+AP++ + + S ++ W
Sbjct: 29308 GCDYQ----FRVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWT 29363
Query: 794 PPAYDGGQPILGYILERKKKKSYRWMRLNFDL-IQELSHEARRMIEGVVYEMRVYAVNAI 852
P YDGG I+GY+LE ++K + +W R++ + I+ + G Y RV AVN
Sbjct: 29364 KPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVK 29423
Query: 853 GMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTT-----------VSLKWRPPERVGAGGL 901
GMS S + P+ P +D+ T VS+ RPP
Sbjct: 29424 GMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIRAGASLRLMVSVSGRPPP------- 29476
Query: 902 DGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARL-LFRVRAHNMAGPGAPVTTTE 960
+ + +G A+ TE S+L+ D + + A N +G + +
Sbjct: 29477 ---VITWSKQGIDLASRAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVK 29533
Query: 961 PVTVQEILQRPRLQLPRHLRQTIQKKV-----GEPVNLLIPFQGKPRPQVTWTKEGQPLA 1015
+++ TI ++ G PVN I + +E A
Sbjct: 29534 VYDTPGPCPSVKVKEVSRDSVTITWEIPTIDGGAPVNNYIVEK----------REAAMRA 29583
Query: 1016 GEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENM--------EDKATLVLQVVDKPS 1067
+ V+ + S T R + V Y V EN+ A LV +V P
Sbjct: 29584 FKTVTTKCSKT----LYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSEV---PL 29636
Query: 1068 PPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWF-------TVLEHYR 1120
P L V D V L W+ P G + L GY ++ T W TVLEH
Sbjct: 29637 VPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEH-- 29694
Query: 1121 RTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEA 1180
V L G Y FR+ +QN G S+ PR +T D
Sbjct: 29695 ----TVTSLNEGEQYLFRIRAQNEKGVSE-----------PRETVTA----VTVQDLRVL 29735
Query: 1181 PSF---TQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLT 1237
P+ T P V AG L + G P P SWF G L E R + + V
Sbjct: 29736 PTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAK 29795
Query: 1238 LEIRKPCPFDGGIYVCRATNLQG 1260
L IR+ D G Y N+ G
Sbjct: 29796 LTIRETTIRDTGEYTLELKNVTG 29818
Score = 108 bits (270), Expect = 3e-23
Identities = 83/275 (30%), Positives = 134/275 (48%), Gaps = 11/275 (4%)
Query: 374 QVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAA 433
++ +G K ++ V+W ++ + ++ SG KY + G KR L + +L D
Sbjct: 12562 EILEGEKAEFVCSISKESFPVQWKRDDKTLE-SGDKYDVIADGKKRVLVVKDATLQDMGT 12620
Query: 434 YQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVEL 493
Y +VG + + L V E + I PL+D V Q V F CEV+ EGA+ KW ++ E
Sbjct: 12621 YVVMVGAARAAAHLTVIEK-LRIVVPLKDTRVKEQQEVVFNCEVNTEGAKAKWFRN--EE 12677
Query: 494 TREETFKYRFKKDGQRHHLIINEAMLEDAGHY--ALCTSGGQ---ALAELIVQEKKLEVY 548
++ KY + + L I +A L+D +Y +L G+ + A LIV+E+ L +
Sbjct: 12678 AIFDSSKYIILQKDLVYTLRIRDAHLDDQANYNVSLTNHRGENVKSAANLIVEEEDLRIV 12737
Query: 549 QSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTP 608
+ + D+ K F C+V+ NV W KNG+E+ D+R+ H LTI D
Sbjct: 12738 EPLKDIETMEKKSVTFWCKVNRLNVTLKWTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGF 12797
Query: 609 ADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQE 643
DE +Y V G ++ A+L +E +FV E
Sbjct: 12798 PDEGEY-IVTAGQDKSV-AELLIIEAPTEFVEHLE 12830
Score = 107 bits (268), Expect = 6e-23
Identities = 72/235 (30%), Positives = 117/235 (49%), Gaps = 8/235 (3%)
Query: 384 TVELADHDAE-VKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEK 442
TVEL + + V+W+KNG ++ S KY G +L I C++ D++ Y +G
Sbjct: 2727 TVELTHPNVKGVQWIKNGVVLE-SNEKYAISVKGTIYSLRIKNCAIVDESVYGFRLGRLG 2785
Query: 443 CSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYR 502
S L V+ V I + +D + V FE VS + VKW VE+ + K+R
Sbjct: 2786 ASARLHVET--VKIIKKPKDVTALENATVAFEVSVSHDTVPVKWFHKSVEIKPSD--KHR 2841
Query: 503 FKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQA 562
+ + H L++ DAG Y + A+L V+ L + +++ ++ V A
Sbjct: 2842 LVSERKVHKLMLQNISPSDAGEYTAVVGQLECKAKLFVET--LHITKTMKNIEVPETKTA 2899
Query: 563 VFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFV 617
F+CEVS NV +WLKNG E+ + K+ G++H+L I + + D A+Y+FV
Sbjct: 2900 SFECEVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFV 2954
Score = 107 bits (268), Expect = 6e-23
Identities = 98/412 (23%), Positives = 161/412 (39%), Gaps = 41/412 (9%)
Query: 868 GPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHT 927
GPP+ P ++ DV+ +++ W+PP+ G + Y VE W G ++ T
Sbjct: 17605 GPPTGPINIL--DVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSK-T 17661
Query: 928 SILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKV 987
+ + L G +FRVRA N G G P+ +T V + + P + + +
Sbjct: 17662 KLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVA------KHKFSPPSPPGKPVVTDI 17715
Query: 988 GE---PVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQ 1044
E V+ +P P + E + + G+ V + +P + F R TY+
Sbjct: 17716 TENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVNKTPIADLKF-RVTGLYEGNTYE 17774
Query: 1045 VTVRIENM--------EDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTE 1096
V EN+ + + P PP + ++ D L W P G +
Sbjct: 17775 FRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGGSP 17834
Query: 1097 LWGYTVQKADKKTMEWFTVLEHYRRTHCV--VPELIIGNGYYFRVFSQNMVGFSDRAATT 1154
+ GY V+ T +W + + C VP LI GN Y FR+ + N+VG +
Sbjct: 17835 ILGYVVECQKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELA 17894
Query: 1155 KEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIA---GYTAMLCCAVRGSPKPK 1211
+ + A D P + R VI G T + V+G P+P
Sbjct: 17895 ESVI---------------AKDILHPPEVELDVTCRDVITVRVGQTIRILARVKGRPEPD 17939
Query: 1212 ISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEAR 1263
I+W K G L + R + + L+I++ D G Y+ A N G A+
Sbjct: 17940 ITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSGHAQ 17991
Score = 106 bits (265), Expect = 1e-22
Identities = 124/571 (21%), Positives = 216/571 (37%), Gaps = 99/571 (17%)
Query: 736 FTVEGAEKEDEGVYTVTVKNPVGEDQVNLT---VKVIDV---PDAPAAPKISNVGEDSCT 789
+ V G + E + + +N G + T K D P P P++ + S +
Sbjct: 21714 YKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSIS 21773
Query: 790 VQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDL-IQELSHEARRMIEGVVYEMRVYA 848
+ W P YDGG I GY++E + W + ++ S+ + E Y++R+YA
Sbjct: 21774 IAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYA 21833
Query: 849 VNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTT----------------VSLKWRP 892
+N+ G+ P+ +P P +E L E D V +K RP
Sbjct: 21834 MNSEGLGEPA-----LVPGTPKAEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRP 21888
Query: 893 PERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGP 952
V G S++ A+++ + +T ++V ++ + + N +G
Sbjct: 21889 APEVKWARDHGESLDK---------ASIESTSSYTLLIVGNVNRFDSGKYILTVENSSGS 21939
Query: 953 GAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQ 1012
+ +L P G P +L + K +TW
Sbjct: 21940 KSAFVNVR------VLDTP----------------GPPQDLKVKEVTKTSVTLTWDP--- 21974
Query: 1013 PLAGEEVSIRNSPTDTILFIRAA-RRVHSGTYQVTVRIENMEDKATLVLQVV-------- 1063
PL I+N + R A V + ++ + +++ +++ + +V+
Sbjct: 21975 PLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLAENEYGIG 22034
Query: 1064 ------------DKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTME 1111
++P PP + + D +V+L W+ P+ G + + GY V+ K + +
Sbjct: 22035 LPAETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDK 22094
Query: 1112 WFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPN 1171
W T + T + LI G Y FRV +QN G SD P + P I
Sbjct: 22095 WATCAT-VKVTEATITGLIQGEEYSFRVSAQNEKGISD-------PRQLSVPVI------ 22140
Query: 1172 YKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFS 1231
A D P+F +V+AG + G P P ++W K+ + L + R S
Sbjct: 22141 --AKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAES 22198
Query: 1232 KQGVLTLEIRKPCPFDGGIYVCRATNLQGEA 1262
+ L I+ C D G YV + TN GEA
Sbjct: 22199 TENNSLLTIKDACREDVGHYVVKLTNSAGEA 22229
Score = 105 bits (263), Expect = 2e-22
Identities = 87/330 (26%), Positives = 141/330 (42%), Gaps = 40/330 (12%)
Query: 644 PPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPE 703
PP I L R DTI V AG + + ++G P P + W K N+ DA +
Sbjct: 15394 PPTIKLRLSVR-GDTIKVKAGEPVHIPADVTGLPMPKIEWSK-----NETVIEKPTDALQ 15447
Query: 704 DTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVN 763
T + V ++ ++ ++ A +ED+G YTVT N +G N
Sbjct: 15448 ITKEE------------------VSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRN 15489
Query: 764 LTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERK--KKKSYRWMRL 821
+ V+V D P P ++++ +SC + W+ P +GG I Y+++++ +K W +
Sbjct: 15490 VHVEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEV 15549
Query: 822 NFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQ-----PFMPIGPPSEPTHL 876
+ E + ++I YE RV AVN G+S + + P+ GPP +P L
Sbjct: 15550 TNTAV-EKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVL 15608
Query: 877 AVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSIL-----V 931
A + ++ + W PP G + GY +E EG W + + V
Sbjct: 15609 A---RTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVGLKGVEFNV 15665
Query: 932 KDLPTGARLLFRVRAHNMAGPGAPVTTTEP 961
L G + FR A N AG G P ++P
Sbjct: 15666 PRLLEGVKYQFRAMAINAAGIGPPSEPSDP 15695
Score = 105 bits (263), Expect = 2e-22
Identities = 85/322 (26%), Positives = 132/322 (40%), Gaps = 40/322 (12%)
Query: 657 DTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKK 716
D +++ +G LR+ + G P P V W K G
Sbjct: 27966 DGLIIKSGESLRIKALVQGRPVPRVTWFK---DG-------------------------- 27996
Query: 717 LLCETEGRVRVETTK---DRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPD 773
E E R+ +E T S+F V A ++ GVYTV KN G + + VKV D P
Sbjct: 27997 --VEIEKRMNMEITDVLGSTSLF-VRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPG 28053
Query: 774 APAAP-KISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHE 832
P + +N+ + T+ W+ P DG PI YI+E+++ W + D + S+
Sbjct: 28054 KVVGPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIE-DKCEAQSYT 28112
Query: 833 ARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPI--GPPSEPTHLAVEDVSDTTVSLKW 890
A ++I G Y+ RV AVN G+ RP + I P P +++ +++L W
Sbjct: 28113 AIKLINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTW 28172
Query: 891 RPPERVGAGGLDGYSVEYCPEGCSEWVAAL-QGLTEHTSILVKDLPTGARLLFRVRAHNM 949
PE G + Y +E + + WV + + T V L G F V A N
Sbjct: 28173 ARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVMAENA 28232
Query: 950 AGPGAPVTTTEPVTVQEILQRP 971
AG G + + +E + P
Sbjct: 28233 AGVGPASGISRLIKCREPVNPP 28254
Score = 105 bits (262), Expect = 3e-22
Identities = 207/979 (21%), Positives = 352/979 (35%), Gaps = 183/979 (18%)
Query: 354 GMRRDEKKSTAFQKKLEPAYQVSKGHKIRLTVELADHDAEVK--------WLKNGQEIQM 405
G + TA + K P + + + E AD + V W K+ +EI+
Sbjct: 6254 GTASSSARLTAREPKKSPFFDIKPVSIDVIAGESADFECHVTGAQPMRITWSKDNKEIRP 6313
Query: 406 SGSKYIFESIGAKRTLTISQCSLADDAAYQCV----VGGEKCSTELFVKEPPVLITRPLE 461
G+ Y +G L I + D Y C VG + CS +L VKEPP + +
Sbjct: 6314 GGN-YTITCVGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKEPPKFVKKLEA 6372
Query: 462 DQLVMVGQRVEFECEVS-EEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLE 520
++ G+ ++ EC++S +V W ++ EL E++KY L INEA E
Sbjct: 6373 SKVAKQGESIQLECKISGSPEIKVSWFRNDSEL--HESWKYNMSFINSVALLTINEASAE 6430
Query: 521 DAGHYALCTSG---GQALAELIVQEKKLEVYQSIADLMVGAK-DQAVFKCEVS-DENVRG 575
D+G Y +C + G A + K V+ + K + +CE+S
Sbjct: 6431 DSGDY-ICEAHNGVGDASCSTALTVKAPPVFTQKPSPVGALKGSDVILQCEISGTPPFEV 6489
Query: 576 VWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPE----GFACNLSAKLHF 631
VW+K+ K++ + K++ L I ++ +D +Y C+ S K
Sbjct: 6490 VWVKDRKQVRNSKKFKITSKHFDTSLHILNLEASDVGEYHCKATNEVGSDTCSCSVKF-- 6547
Query: 632 MEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGN 691
+EPP+ ++ DT ++ G+ + L + G +V+W K
Sbjct: 6548 ----------KEPPRF----VKKLSDTSTLI-GDAVELRAIVEGFQPISVVWLK------ 6586
Query: 692 KAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTV 751
D G+ ++ E+E R+ + + + E + G Y
Sbjct: 6587 ------------DRGE---------VIRESE-NTRISFIDNIATLQLGSPEASNSGKYIC 6624
Query: 752 TVKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPI-LGYILER 810
+KN G + + + V++ P EP G P L ++
Sbjct: 6625 QIKNDAGMRECSAVLTVLEPARIIEKP--------------EPMTVTTGNPFALECVVTG 6670
Query: 811 KKKKSYRWMRLNFDLIQELSHE-------------ARRMIEGVVYEMRVYAVNAIGMSRP 857
+ S +W + +L + H M + +Y V N++G S
Sbjct: 6671 TPELSAKWFKDGRELSADSKHHITFINKVASLKIPCAEMSDKGLYSFEV--KNSVGKSNC 6728
Query: 858 SPASQPFMPIGPPSEPTHLA-VEDVSDTTVSLKWR----PPERVG--AGGLDGYSVEYCP 910
+ + I PPS L V + +V L+ R P VG G + S C
Sbjct: 6729 TVSVHVSDRIVPPSFIRKLKDVNAILGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQ 6788
Query: 911 EGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGP---GAPVTTTEPVTVQEI 967
SE V L L++ TG ++ A N+AG A +T EP + +
Sbjct: 6789 SSFSENVCTL------NLSLLEPSDTG---IYTCVAANVAGSDECSAVLTVQEPPSFE-- 6837
Query: 968 LQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLA-GEEVSIRNSPT 1026
Q P +++ G + +G P +V W K + L GE +I
Sbjct: 6838 -QTP---------DSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVPGESCNISLEDF 6887
Query: 1027 DTILFIRAARRVHSGTYQVTVRIEN----------MEDKATLVLQVVD---KPSPPQDLR 1073
T L + + + SG Y V + +++ AT V ++ D + P L
Sbjct: 6888 VTELELFEVQPLESGDYSCLVTNDAGSASCTTHLFVKEPATFVKRLADFSVETGSPIVLE 6947
Query: 1074 VTDAWGLNVALEW-KPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIG 1132
T +++ W K + +E T+ + + +E Y + C++
Sbjct: 6948 ATYTGTPPISVSWIKDEYLISQSERCSITMTEKSTILEILESTIEDYAQYSCLI------ 7001
Query: 1133 NGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSV 1192
+N G A + E P F +PL +
Sbjct: 7002 ---------ENEAGQDICEA---------------------LVSVLEPPYFIEPLEHVEA 7031
Query: 1193 IAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYV 1252
+ G A L C V G+P+ +ISW+K L ++M K V +L I K D G Y
Sbjct: 7032 VIGEPATLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYS 7091
Query: 1253 CRATNLQGEARCECRLEVR 1271
C+A N G L ++
Sbjct: 7092 CKADNSVGAVASSAVLVIK 7110
Score = 105 bits (261), Expect = 4e-22
Identities = 130/548 (23%), Positives = 207/548 (37%), Gaps = 57/548 (10%)
Query: 738 VEGAEKEDEGVYTVTVKNPVGEDQ---VNLTVKVIDV---PDAPAAPKISNVGEDSCTVQ 791
V G ++ E + V+ +N G + + K D P P I + ++S T+
Sbjct: 23880 VTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLA 23939
Query: 792 WEPPAYDGGQPILGYILERKKKKSYRWMRLNFDL-IQELSHEARRMIEGVVYEMRVYAVN 850
W P YDGG ILGY++E K W + ++ E ++ E Y++RV A+N
Sbjct: 23940 WGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALN 23999
Query: 851 AIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCP 910
+G+ + P P + + + R V AGG + +
Sbjct: 24000 KVGLGEATSVPGTVKPEDKLEAP---------ELDLDSELRKGIVVRAGGSARIHIPFKG 24050
Query: 911 EGCSE--WVAALQGLTE---------HTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTT 959
E W T+ +T + + + + ++ N +G + T
Sbjct: 24051 RPTPEITWSREEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVT- 24109
Query: 960 EPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEV 1019
V V + P+ + +R+ V EP +I K + V +E A V
Sbjct: 24110 --VKVLDTPGPPQNLAVKEVRKDSAFLVWEPP--IIDGGAKVKNYVIDKRESTRKAYANV 24165
Query: 1020 SIRNSPTDTILFIRAARRVHSGTYQVTVRIEN-----MEDKATLVLQVVDKPSPPQDLRV 1074
S + S T + Y V EN + + ++ + PSPP + +
Sbjct: 24166 SSKCSKTS----FKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEPPSPPGKVTL 24221
Query: 1075 TDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNG 1134
TD + +L W+ P+ G + + GY V+ K T +W V E + + VV L G
Sbjct: 24222 TDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAES-KVCNAVVTGLSSGQE 24280
Query: 1135 YYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIA 1194
Y FRV + N G SD P + P I A D + PS P S+ A
Sbjct: 24281 YQFRVKAYNEKGKSD-------PRVLGVPVI--------AKDLTIQPSLKLPFNTYSIQA 24325
Query: 1195 GYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCR 1254
G + V G P+P ISW K+G L + R + L I++ D G Y
Sbjct: 24326 GEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVT 24385
Query: 1255 ATNLQGEA 1262
ATN G A
Sbjct: 24386 ATNSAGTA 24393
Score = 104 bits (260), Expect = 5e-22
Identities = 129/579 (22%), Positives = 235/579 (40%), Gaps = 81/579 (13%)
Query: 725 VRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPKISNVG 784
+ V K++S+ K ++G+ P+ ++ +T +V D+ D P A +G
Sbjct: 27520 IEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPITVKELIITPEV-DLSDIPGAQVTVRIG 27578
Query: 785 EDSCTVQWEPPAYDGGQPILGYI---LERKKKKSYRWMRLNFDLIQELSHEARRMIEGVV 841
+ V E P +P + ++ L K+ + R+ + + + + A++ G
Sbjct: 27579 HN---VHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKN-AKKEHGGKY 27634
Query: 842 YEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTH-LAVEDVSDTTVSLKWRPPERVGAGG 900
+ AV I + P + + +GPPS+P + +++ +V L W PE G G
Sbjct: 27635 TVILDNAVCRIAV----PIT--VITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGE 27688
Query: 901 LDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTE 960
+ YS+E + W + T+ V +L A FRVRA N G ++
Sbjct: 27689 ITCYSIEKRETSQTNWKMVCSSVAR-TTFKVPNLVKDAEYQFRVRAENRYG------VSQ 27741
Query: 961 PVTVQEILQRPRLQLPRHL-RQTIQKKVGEPVNLL--------------IPFQGKPRPQV 1005
P+ I+ + + ++P + I + ++L + K R +
Sbjct: 27742 PLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSI 27801
Query: 1006 TWTKEG-QPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENME--------DKA 1056
W K P++G E RA V YQ V EN K
Sbjct: 27802 LWQKVNTSPISGREY-------------RATGLVEGLDYQFRVYAENSAGLSSPSDPSKF 27848
Query: 1057 TLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEW---- 1112
TL + VD P P + VT + L+W PP G +++ GY+++K W
Sbjct: 27849 TLAVSPVDPPGTPDYIDVTRE---TITLKWNPPLRDGGSKIVGYSIEKRQGNE-RWVRCN 27904
Query: 1113 FTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNY 1172
FT + + T V L G+ Y FR+ ++N VG + + + + PP
Sbjct: 27905 FTDVSECQYT---VTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENV---PP-- 27956
Query: 1173 KALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSK 1232
++F P + L+ +S G + + V+G P P+++WFK+G+++ + +
Sbjct: 27957 -IVEFG--PEYFDGLIIKS---GESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDV 28010
Query: 1233 QGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVR 1271
G +L +R G+Y A N G A+ E +++V+
Sbjct: 28011 LGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQ 28049
Score = 104 bits (259), Expect = 6e-22
Identities = 210/960 (21%), Positives = 349/960 (36%), Gaps = 158/960 (16%)
Query: 360 KKSTAFQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKR 419
K+ +F KK+E V K + + WLK+ Q + + YI + +
Sbjct: 5045 KEPPSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQILDEDDNVYI-SFVDSVA 5103
Query: 420 TLTISQCSLADDAAYQCVV----GGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFEC 475
TL I Y C G E+C L V+EP ++ + V + EC
Sbjct: 5104 TLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQEPAQIVEKAKSVD-VTEKDPMTLEC 5162
Query: 476 EVS-EEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALC------ 528
V+ +VKWLKDG ++ F F+ + I M +D+G Y
Sbjct: 5163 VVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVASFR--IQSVMKQDSGQYTFKVENDFG 5220
Query: 529 TSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDE-NVRGVWLKNGKELVPD 587
+S A ++ Q + + + +C+VS + W K+GKE+
Sbjct: 5221 SSSCDAYLRVLDQNIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKEISTS 5280
Query: 588 SRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKI 647
++ ++ R L ++++ D A+Y+ A + A + VK EPP
Sbjct: 5281 AKYRLVCHERSVSLEVNNLELEDTANYTCKVSNVAGD-DACSGILTVK-------EPPSF 5332
Query: 648 HLDCPGR---IPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPED 704
L PGR IPD+ V + G P + W K
Sbjct: 5333 -LVKPGRQQAIPDSTV-------EFKAILKGTPPFKIKWFK------------------- 5365
Query: 705 TGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNL 764
D E V K EG +T ++++V+ ++ G YT V N VG D
Sbjct: 5366 --DDVELVSGPKCFIGLEG-----STSFLNLYSVDASK---TGQYTCHVTNDVGSDSCTT 5415
Query: 765 TVKVIDVP---DAPAAPKISNVGEDS---CTVQWEPPAYDGGQPILGYILERKKKK---- 814
+ V + P A KI G+ S C + G P + + R + +
Sbjct: 5416 MLLVTEPPKFVKKLEASKIVKAGDSSRLECKI--------AGSPEIRVVWFRNEHELPAS 5467
Query: 815 -SYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEP 873
YR ++ + ++++ + + E + A + ++ P PP
Sbjct: 5468 DKYRMTFIDSVAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEPPVFSSFPP--- 5524
Query: 874 THLAVEDVSDTTVSLKWR----PPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSI 929
VE + + VSL+ PP V Y + ++ A + HTSI
Sbjct: 5525 ---IVETLKNAEVSLECELSGTPPFEV-----VWYKDKRQLRSSKKYKIASKNF--HTSI 5574
Query: 930 LVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQ--TIQKKV 987
+ ++ T + +A N G V T + L+ P PR + + ++
Sbjct: 5575 HILNVDTSDIGEYHCKAQNEVGSDTCVCTVK-------LKEP----PRFVSKLNSLTVVA 5623
Query: 988 GEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTV 1047
GEP L +G V W KE + + E +IR + + + ++ A+ + +
Sbjct: 5624 GEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRITFVENVATLQFAKAEPANAGKYIC 5683
Query: 1048 RIEN----MEDKATLVL----QVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTEL-- 1097
+I+N E+ ATL++ +V+K P +T G LE K G EL
Sbjct: 5684 QIKNDGGMRENMATLMVLEPAVIVEKAGP-----MTVTVGETCTLECKV---AGTPELSV 5735
Query: 1098 -W---GYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAAT 1153
W G + + K ++ + R + E Y F+V QN VG S A
Sbjct: 5736 EWYKDGKLLTSSQKHKFSFYNKISSLR---ILSVERQDAGTYTFQV--QNNVGKSSCTAV 5790
Query: 1154 TKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKIS 1213
D + PSFT+ L N + G + +L C V GS ++
Sbjct: 5791 V------------------DVSDRAVPPSFTRRLKNTGGVLGASCILECKVAGSSPISVA 5832
Query: 1214 WFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVRVP 1273
WF + A+++ V TL++ D G Y C A N+ G C L V+ P
Sbjct: 5833 WFHEKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQEP 5892
Score = 103 bits (257), Expect = 1e-21
Identities = 124/529 (23%), Positives = 187/529 (35%), Gaps = 95/529 (17%)
Query: 772 PDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDL-IQELS 830
P PA PK+ + S ++ W PAYDGG PI+GY++E K+ S W+R N +Q+
Sbjct: 19589 PGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTR 19648
Query: 831 HEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTT----- 885
E ++E Y+ RVYAVN IG S PS P P D+ T
Sbjct: 19649 FEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAG 19708
Query: 886 ------VSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGAR 939
V +K RPP ++ W L + + +K T
Sbjct: 19709 VTMRLYVPVKGRPPPKI------------------TWSKPNVNLRDRIGLDIKS--TDFD 19748
Query: 940 LLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKV----GEPVNLLI 995
R N G + T E ++ TI KV G PVN+ +
Sbjct: 19749 TFLRCENVNKYDAGKYILTLENSCGKK-------------EYTIVVKVLDTPGPPVNVTV 19795
Query: 996 PFQGKPRPQVTWTKE----GQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIEN 1051
K VTW G P+ V R++ ++ V + + + R+ N
Sbjct: 19796 KEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAER------KSWSTVTTECSKTSFRVAN 19849
Query: 1052 MEDKATLVLQVVDK--------------------PSPPQDLRVTDAWGLNVALEWKPPQD 1091
+E+ + +V + P P DL+V + ++ WK P
Sbjct: 19850 LEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVVDLKVRSVSKSSCSIGWKKPHS 19909
Query: 1092 VGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRA 1151
G + + GY V ++ +W V++ + +L G Y FRV ++N G
Sbjct: 19910 DGGSRIIGYVVDFLTEEN-KWQRVMKSLSLQYSA-KDLTEGKEYTFRVSAENENG----E 19963
Query: 1152 ATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPK 1211
T E + R + LD P S L ++G P P
Sbjct: 19964 GTPSEITVVARDDVVAPD-----LDLKGLPDLCYLAKENS-----NFRLKIPIKGKPAPS 20013
Query: 1212 ISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQG 1260
+SW K L D R + S TL + D G Y N+ G
Sbjct: 20014 VSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAG 20062
Score = 102 bits (255), Expect = 2e-21
Identities = 196/928 (21%), Positives = 335/928 (36%), Gaps = 153/928 (16%)
Query: 391 DAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCV----VGGEKCSTE 446
+ + W K +++ S Y + +L I++ +D Y C VG S
Sbjct: 7048 EIRISWYKEHTKLR-SAPAYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAV 7106
Query: 447 LFVK--EPPVLITRPLEDQLVMVGQRVEFECEVS-EEGAQVKWLKDGVELTREETFKYRF 503
L +K + P R L+D +G V FEC ++ E QV W KDGV L + + F
Sbjct: 7107 LVIKARKLPPFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGVLLKDDANLQTSF 7166
Query: 504 KKDGQRHHLIINEAMLEDAGHYAL--CTSGG-----QALAELIVQEKKLEVYQSI----A 552
H++ + + D H C++ + A+LI+ E ++ + +
Sbjct: 7167 V-----HNVATLQILQTDQSHIGQYNCSASNPLGTASSSAKLILSEHEVPPFFDLKPVSV 7221
Query: 553 DLMVGAKDQAVFKCEVSDEN-VRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADE 611
DL +G + FKC V+ ++ W K+ +E+ P K++ + LT+ V D
Sbjct: 7222 DLALG--ESGTFKCHVTGTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDA 7279
Query: 612 ADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDV 671
Y+ +A N++ K + + QEPP+ ++ + +V R +
Sbjct: 7280 GQYTC----YASNIAGK----DSCSAQLGVQEPPRF----IKKLEPSRIVKQDEFTRYEC 7327
Query: 672 PISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTK 731
I G P V+W K T+ + + R+
Sbjct: 7328 KIGGSPEIKVLWYKDETE-----------------------------IQESSKFRMSFVD 7358
Query: 732 DRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPKISNV--GED--- 786
++ + ED G YT N G + ++KV + P P G D
Sbjct: 7359 SVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKEPPIFRKKPHPIETLKGADVHL 7418
Query: 787 SCTVQWEPPAYDGGQPILGYILERKKK--KSYRWMRLNF-DLIQELSHEARRMIEGVVYE 843
C +Q PP + + Y +R+ + K Y+ M NF I L+ +A + E
Sbjct: 7419 ECELQGTPPFH-----VSWYKDKRELRSGKKYKIMSENFLTSIHILNVDA-----ADIGE 7468
Query: 844 MRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDG 903
+ A N +G S + + P V+ +SD + + + G +
Sbjct: 7469 YQCKATNDVG----SDTCVGSIALKAPPR----FVKKLSDISTVVGKEVQLQTTIEGAEP 7520
Query: 904 YSV-------EYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPV 956
SV E E + W++ + + V+ G + + N AG
Sbjct: 7521 ISVVWFKDKGEIVRESDNIWISYSENIATLQFSRVEPANAGK---YTCQIKNDAGMQECF 7577
Query: 957 TTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAG 1016
T + I+++P ++I+ G+ L G P W K+G+ L
Sbjct: 7578 ATLSVLEPATIVEKP---------ESIKVTTGDTCTLECTVAGTPELSTKWFKDGKELTS 7628
Query: 1017 E---EVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPP---Q 1070
+ ++S N + L I SG Y V+ +D T LQV D+ PP +
Sbjct: 7629 DNKYKISFFNKVSG--LKIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRTVPPSFTR 7686
Query: 1071 DLRVTDAW-GLNVALEWK----PPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCV 1125
L+ T+ G +V +E K PP V W + + T+ ++
Sbjct: 7687 KLKETNGLSGSSVVMECKVYGSPPISVS----WFHEGNEISSGRKYQTTLTDN--TCALT 7740
Query: 1126 VPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQ 1185
V L + + + NM G + +A L E PSF Q
Sbjct: 7741 VNMLEESDSGDYTCIATNMAGSDECSA---------------------PLTVREPPSFVQ 7779
Query: 1186 PLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCP 1245
V+ G V+G+P +SWFK +L R + + V LE+
Sbjct: 7780 KPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGSSELVPGDRCNVSLEDSVAELELFDVDT 7839
Query: 1246 FDGGIYVCRATNLQGEARCECRLEVRVP 1273
G Y C +N G+A C L ++ P
Sbjct: 7840 SQSGEYTCIVSNEAGKASCTTHLYIKAP 7867
Score = 102 bits (255), Expect = 2e-21
Identities = 114/505 (22%), Positives = 205/505 (40%), Gaps = 45/505 (8%)
Query: 704 DTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVN 763
D G E + L T+ VRV + + G + E + V N GE + +
Sbjct: 14010 DGGAKIESYVIEMLKTGTDEWVRVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPS 14069
Query: 764 ------LTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYR 817
L + + P P ++ N+ +++ ++W P DGG PI YI+E++ +
Sbjct: 14070 EPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKG 14129
Query: 818 WMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMP---IGPPSEPT 874
W ++ +++ + EG +Y RV A NAIG S + + P P
Sbjct: 14130 WQTVD-TTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPY 14188
Query: 875 HLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDL 934
LAV DV+ V LKW PP+ G + Y +E + WV A + + V D+
Sbjct: 14189 ALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDV 14248
Query: 935 PTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLL 994
G + F+VRA N AG G P TE +++++ P L H+ +K + +
Sbjct: 14249 IEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIA--IAWK 14306
Query: 995 IPFQGKPRPQVTWTKEGQPLAGEE-VSIRNSPTDTILFIRAARRVHSGTYQVTVRIEN-- 1051
P + P + + E P+ E+ + + + P + F V Y + VR N
Sbjct: 14307 PPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAI 14366
Query: 1052 -MEDKATLVLQVVDKPS--------PPQDLRVTDAWGLNVALEWKP-PQDVGNTELWGYT 1101
+ + + + VV K D+ V + L++ + ++ P + G
Sbjct: 14367 GVSEPSEISENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKE 14426
Query: 1102 VQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIP 1161
V+ +D+ TM+ + H VP+ + + + + +N +G S A+ + + +P
Sbjct: 14427 VKASDRLTMK-----NDHISAHLEVPKSVRADAGIYTITLENKLG-SATASINVKVIGLP 14480
Query: 1162 RP--------------GITYEPPNY 1172
P +T+EPP +
Sbjct: 14481 GPCKDIKASDITKSSCKLTWEPPEF 14505
Score = 102 bits (255), Expect = 2e-21
Identities = 86/332 (25%), Positives = 131/332 (39%), Gaps = 39/332 (11%)
Query: 644 PPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPE 703
PP +HLD D + + G L SG P P V W K
Sbjct: 16817 PPTLHLD----FRDKLTIRVGEAFALTGRYSGKPKPKVSWFK------------------ 16854
Query: 704 DTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVN 763
D D E + R ++TT A++ D G Y V V+N G +
Sbjct: 16855 DEADVLE-----------DDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGF 16903
Query: 764 LTVKVIDVPDAPAAP-KISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLN 822
V V+D P P P V +D + W+PP DGG I YI+E+K+ WM +
Sbjct: 16904 CQVNVVDRPGPPVGPVSFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPVT 16963
Query: 823 FDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRP--SPASQPFMPIGPPSEPTHLAVED 880
+ + + +++EG Y R++A N G+S P S + + P P V +
Sbjct: 16964 -SASAKTTCKVSKLLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTE 17022
Query: 881 VSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQG-LTEHTSILVKDLPTGAR 939
V+ + + W P G + Y +E W + + +T V DL G +
Sbjct: 17023 VTKDSALVTWNKPHD-GGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQ 17081
Query: 940 LLFRVRAHNMAGPGAPVTTTEPVTVQEILQRP 971
FRV A N G G P ++PV ++ + +P
Sbjct: 17082 YEFRVSAENEIGIGDPSPPSKPVFAKDPIAKP 17113
Score = 102 bits (254), Expect = 2e-21
Identities = 203/958 (21%), Positives = 349/958 (36%), Gaps = 162/958 (16%)
Query: 365 FQKKLEPAYQVSKGHKIRLTVELADH-DAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTI 423
F KKLE + V G RL ++A + V W +N E+ S KY I + + +
Sbjct: 5425 FVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPAS-DKYRMTFIDSVAVIQM 5483
Query: 424 SQCSLADDAAYQCVV----GGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSE 479
+ S D + C G CST++ VKEPPV + P + + V ECE+S
Sbjct: 5484 NNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEPPVFSSFPPIVE-TLKNAEVSLECELSG 5542
Query: 480 EGA-QVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAEL 538
+V W KD +L + +K K H++ + D G Y C + + ++
Sbjct: 5543 TPPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHILNVDT--SDIGEYH-CKAQNEVGSDT 5599
Query: 539 IVQEKKLE----VYQSIADLMVGAKDQAVFKCEVSDENVRGV-WLKNGKELVPDSR-IKV 592
V KL+ + L V A + A + + V WLK +E++ +S I++
Sbjct: 5600 CVCTVKLKEPPRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRI 5659
Query: 593 SHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCP 652
+ + V L PA+ Y ++K D R+ + + P
Sbjct: 5660 TFVENVATLQFAKAEPANAGKY----------------ICQIKNDGGMRENMATLMVLEP 5703
Query: 653 GRIPDT---IVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSD 709
I + + V G L+ ++G P +V
Sbjct: 5704 AVIVEKAGPMTVTVGETCTLECKVAGTPELSV---------------------------- 5735
Query: 710 EWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVI 769
EW D KLL ++ + + S + E++D G YT V+N VG+ V V
Sbjct: 5736 EWYKDGKLLTSSQ-KHKFSFYNKISSLRILSVERQDAGTYTFQVQNNVGKSSCTAVVDVS 5794
Query: 770 DVPDAPA-APKISNVG---EDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDL 825
D P+ ++ N G SC ++ + G PI S W
Sbjct: 5795 DRAVPPSFTRRLKNTGGVLGASCILECK---VAGSSPI-----------SVAWF------ 5834
Query: 826 IQELSHEARRMIEGVVY-------------------EMRVYAVNAIGMSRPSPASQPFMP 866
HE +++ G Y +M Y A ++
Sbjct: 5835 -----HEKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTV 5889
Query: 867 IGPPS---EPTHLAV---EDVSDTTVSLKWRPPERVG--AGGLDGYSVEYCPEGCSEWVA 918
PPS EP L V ++V+ T+V ++ PP +V G + + C + VA
Sbjct: 5890 QEPPSFVKEPEPLEVLPGKNVTFTSV-IRGTPPFKVNWFRGARELVKGDRCNIYFEDTVA 5948
Query: 919 ALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRH 978
L+ + D+ + N AG + T + ++ P L R
Sbjct: 5949 ELE-------LFNIDISQSGE--YTCVVSNNAGQAS-------CTTRLFVKEPAAFLKRL 5992
Query: 979 LRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPL-AGEEVSIRNSPTDTILFIRAARR 1037
+++ G+ + L + G VTW K+G + E+ +I + IL I + +
Sbjct: 5993 SDHSVEP--GKSIILESTYTGTLPISVTWKKDGFNITTSEKCNIVTTEKTCILEILNSTK 6050
Query: 1038 VHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTD-AWGLNVALEWKPPQDVGNTE 1096
+G Y + E D ++ ++ P +L + A G +V+L+ + T
Sbjct: 6051 RDAGQYSCEIENEAGRDVCGALVSTLEPPYFVTELEPLEAAVGDSVSLQCQVAGTPEITV 6110
Query: 1097 LWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKE 1156
W Y + T E+ T + T V ++ I + + ++N +G +
Sbjct: 6111 SW-YKGDTKLRPTPEYRTYFTNNVAT-LVFNKVNINDSGEYTCKAENSIGTASSKTV--- 6165
Query: 1157 PVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFK 1216
++ + PSF + L + G L C + GS ++ W++
Sbjct: 6166 ---------------FRIQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYR 6210
Query: 1217 NGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVRVPQ 1274
+G+ L +D + V TL+I + G Y C A+N G A RL R P+
Sbjct: 6211 DGVLLRDDENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARLTAREPK 6268
Score = 102 bits (253), Expect = 3e-21
Identities = 150/635 (23%), Positives = 235/635 (37%), Gaps = 110/635 (17%)
Query: 680 TVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVE 739
TV+W +RP D D DKK L +V ET +D V
Sbjct: 27083 TVVW-----------SRPIADGGSDISGYFLEKRDKKSLGWF--KVLKETIRDTRQ-KVT 27128
Query: 740 GAEKEDEGVYTVTVKNPVGE------DQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWE 793
G + + Y V N G+ + ID P PA +I++ + S T+ W
Sbjct: 27129 GLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSITLGWS 27188
Query: 794 PPAYDGGQPILGYILERKKKKSYRWMRLNFD-LIQELSHEARRMIEGVVYEMRVYAVNAI 852
P YDGG + GY++E ++ + W ++ ++ + + GV Y RV AVN
Sbjct: 27189 KPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCA 27248
Query: 853 GMSRPSPASQPFMP---IGPPSEPTHLAV---------EDVSDTTVSLKWRPPERV---- 896
G P ++P + P +A+ EDV + K RPP V
Sbjct: 27249 GQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAGEDVQ-VLIPFKGRPPPTVTWRK 27307
Query: 897 ---GAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSIL----VKDLPTGARLLFRVRAHNM 949
G YS+E T+ +S+L V TG +L
Sbjct: 27308 DEKNLGSDARYSIEN---------------TDSSSLLTIPQVTRNDTGKYILTIEN---- 27348
Query: 950 AGPGAPVTTTEPVTVQEILQRP----RLQLPRHLRQTIQKKVGEP--------VNLLIPF 997
G G P ++T V ++L P +LQ+ R T+ P +N +I
Sbjct: 27349 -GVGEPKSSTVSV---KVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVI-- 27402
Query: 998 QGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKAT 1057
+ + + TW+ + + + T F R G + + T
Sbjct: 27403 EKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPC--------ETT 27454
Query: 1058 LVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLE 1117
++ + P+P +DL + D+ +V L W P G + + Y V++ K W +
Sbjct: 27455 EPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERKGKGEQTW-SHAG 27513
Query: 1118 HYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDF 1177
+ V +L + FRVF++N G SD T P+ + IT E +D
Sbjct: 27514 ISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSD--PVTIGPITVKELIITPE------VDL 27565
Query: 1178 SEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLT 1237
S+ P +V G+ L +G PKP ISW K+GL L E R + +T
Sbjct: 27566 SDIPG-----AQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKIT 27620
Query: 1238 LEIRKPCPFDGGIYVCRATNLQGEARCECRLEVRV 1272
L I+ GG Y N CR+ V +
Sbjct: 27621 LSIKNAKKEHGGKYTVILDN------AVCRIAVPI 27649
Score = 101 bits (252), Expect = 4e-21
Identities = 134/560 (23%), Positives = 208/560 (37%), Gaps = 74/560 (13%)
Query: 736 FTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPP 795
+TV+G ++ D Y V+ N VG+ + + K I D A P + D T++
Sbjct: 16776 YTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHLDFRDKLTIRV--- 16832
Query: 796 AYDGGQPILGYILERKKKKSYRWMRLNFDLIQE-LSH-------------EARRMIEG-- 839
G L K K W + D++++ +H +A+R G
Sbjct: 16833 ---GEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKY 16889
Query: 840 -VVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGA 898
VV E + G + + +P P+GP S ++V+ + + W+PP G
Sbjct: 16890 CVVVENSTGSRK--GFCQVNVVDRPGPPVGPVS------FDEVTKDYMVISWKPPLDDGG 16941
Query: 899 GGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTT 958
+ Y +E G W+ + T+ V L G +FR+ A N+ G
Sbjct: 16942 SKITNYIIEKKEVGKDVWMPVTSASAK-TTCKVSKLLEGKDYIFRIHAENLYG------I 16994
Query: 959 TEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLI---PFQG-KPRPQVTWTKEGQPL 1014
++P+ + + R ++P Q I +V + L+ P G KP K + +
Sbjct: 16995 SDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHDGGKPITNYILEKR-ETM 17053
Query: 1015 AGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENM--------EDKATLVLQVVDKP 1066
+ + P R + Y+ V EN K + KP
Sbjct: 17054 SKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKP 17113
Query: 1067 SPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVL---EHYRRTH 1123
SPP + D +V L W+PP+ G +++ GY V+ EW E T
Sbjct: 17114 SPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPETK 17173
Query: 1124 CVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGIT---YEPPNYKALDFSEA 1180
V L G Y FRV + N G SD P +P P + EPP LD + A
Sbjct: 17174 YKVTGLRDGQTYKFRVLAVNAAGESD-------PAHVPEPVLVKDRLEPPEL-ILDANMA 17225
Query: 1181 PSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEI 1240
+ + G T L ++G P PK++W K D AR + LEI
Sbjct: 17226 RE-------QHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGS--KLEI 17276
Query: 1241 RKPCPFDGGIYVCRATNLQG 1260
R DGGIY N G
Sbjct: 17277 RNAAHEDGGIYSLTVENPAG 17296
Score = 101 bits (251), Expect = 5e-21
Identities = 79/286 (27%), Positives = 133/286 (46%), Gaps = 11/286 (3%)
Query: 359 EKKSTAFQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAK 418
E+ F K LE V KG + L+ EL + + +V W K+G+ + + + IG
Sbjct: 11208 EELPVRFVKTLEEEVTVVKGQPLYLSCEL-NKERDVVWRKDGKIVVEKPGRIVPGVIGLM 11266
Query: 419 RTLTISQCSLADDAAYQCVVGGE---KCSTELFVKEPPVL---ITRPLEDQLVMVGQRVE 472
R LTI+ D Y V +CS+ VK V+ + +P+ DQ V
Sbjct: 11267 RALTINDADDTDAGTYTVTVENANNLECSS--CVKVVEVIRDWLVKPIRDQHVKPKGTAI 11324
Query: 473 FECEVSEEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGG 532
F C+++++ +KW K E+ E K +DG +L I AM ED YA+ G
Sbjct: 11325 FACDIAKDTPNIKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEGK 11384
Query: 533 QALAELIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKV 592
+ A+L + E+++E+ + I D+ + K+ A F E+S+ ++ G W G+ L P ++
Sbjct: 11385 RYPAKLTLGEREVELLKPIEDVTIYEKESASFDAEISEADIPGQWKLKGELLRPSPTCEI 11444
Query: 593 SHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDF 638
G LT+ V D+A + + +A L E+++DF
Sbjct: 11445 KAEGGKRFLTLHKV-KLDQAG-EVLYQALNAITTAILTVKEIELDF 11488
Score = 101 bits (251), Expect = 5e-21
Identities = 142/653 (21%), Positives = 242/653 (37%), Gaps = 78/653 (11%)
Query: 661 VVAGNKLRLDVPISGDP-----------APTVIWQKAITQGNKAPARPAPDAPEDTGDSD 709
++A NK + P+ +P AP ++T+ + P+ + +
Sbjct: 16291 IMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTG 16350
Query: 710 EWVFDKKLLCETEGRVRVETTKDRSI---FTVEGAEKEDEGVYTVTVKNPVGEDQVNL-- 764
W+ K + RV + K ++ + V G + + + V N G +L
Sbjct: 16351 YWLEMKDTTSKRWKRVNRDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPS 16410
Query: 765 ---TVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRL 821
T + P P PK+++ + S ++W PP DGG + GYI+E K++ W +
Sbjct: 16411 DPATARDPIAPPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKG 16470
Query: 822 NFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDV 881
++ + EG Y+ RV AVN G+ P + P V
Sbjct: 16471 KDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASV 16530
Query: 882 SDTTVSLKWRPPERVGAGGLDGYS--VEYCPEGCSEW---------VAALQGLTEHTSIL 930
D V V AGG+ V P W A ++ +S++
Sbjct: 16531 RDRIV---------VHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMV 16581
Query: 931 VKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKV--- 987
+K+ + ++ + A N AG + + V + P L +L K
Sbjct: 16582 IKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLA--HNLTNESCKLTWFS 16639
Query: 988 -----GEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGT 1042
G P+ + + + + WT + + +++ F R A G
Sbjct: 16640 PEDDGGSPITNYV-IEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGM 16698
Query: 1043 YQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTV 1102
+E E A ++ + + P P+DL V + V L W PP+ G +E+ Y +
Sbjct: 16699 GPF---VETSE--ALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVL 16753
Query: 1103 QKADKKTMEWFTVL-EHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIP 1161
+ T ++ V ++ V L G+ Y +RV + N+VG +P F
Sbjct: 16754 ESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQG-------KPSFCT 16806
Query: 1162 RPGITYE----PPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKN 1217
+P IT + PP LDF + ++ G L G PKPK+SWFK+
Sbjct: 16807 KP-ITCKDELAPPTLH-LDFRD---------KLTIRVGEAFALTGRYSGKPKPKVSWFKD 16855
Query: 1218 GLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
D+ ED R + + L LE K D G Y N G + C++ V
Sbjct: 16856 EADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNV 16908
Score = 100 bits (250), Expect = 7e-21
Identities = 118/495 (23%), Positives = 197/495 (39%), Gaps = 46/495 (9%)
Query: 736 FTVEGAEKEDEGVYTVTVKNPVG---EDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQW 792
F G E+ E + V+ +N VG +V+ D D P P+ V +S T+QW
Sbjct: 22400 FKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAIIVTRNSVTLQW 22459
Query: 793 EPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAI 852
+ P YDGG I GYI+E+K+ RWM+ +F I + E ++E YE RV A NA
Sbjct: 22460 KKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVIARNAA 22519
Query: 853 GMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEG 912
G+ S + +P ++++ T+ + +V A D Y P
Sbjct: 22520 GVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDA---DIYGK---PIP 22573
Query: 913 CSEWVAALQGLTEHTSILVKDLPTGARL----LFRVRAHNMAGPGAPVTTTEPVTVQ-EI 967
+W+ Q L+ + +K L RV + N V VTV ++
Sbjct: 22574 TIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKV 22633
Query: 968 LQRPRLQLPRHLRQTIQKKVGEPVNLL--IPFQGKPRPQVTWTKEGQPLAGEEVSIRNSP 1025
L RP P I E L P Q + + E + + ++ ++
Sbjct: 22634 LDRPG---PPEGPVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVDAN 22690
Query: 1026 TDTILFIRAARRVHSGTYQVTVRIEN-------MEDKATLVLQVVDKPSPPQDLRVTDAW 1078
T L + + + Y + N +E + + P P+ VT
Sbjct: 22691 VQT-LSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVT 22749
Query: 1079 GLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYR---RTHCVVPELIIGNGY 1135
++ + W+ P G +E+ GY ++K DK+ + W H R V LI + Y
Sbjct: 22750 KDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRC--HKRLIGELRLRVTGLIENHDY 22807
Query: 1136 YFRVFSQNMVGFSDRAATTK-----EPVFIPRPGITYEPPNYKALDFSEAP---SFTQPL 1187
FRV ++N G S+ + + +P++ P P P N K +D + + S+++P+
Sbjct: 22808 EFRVSAENAAGLSEPSPPSAYQKACDPIYKPGP-----PNNPKVIDITRSSVFLSWSKPI 22862
Query: 1188 VNRSV-IAGYTAMLC 1201
+ I GY C
Sbjct: 22863 YDGGCEIQGYIVEKC 22877
Score = 100 bits (248), Expect = 1e-20
Identities = 107/487 (21%), Positives = 186/487 (38%), Gaps = 42/487 (8%)
Query: 800 GQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSP 859
G+P+ L R MR N ++ E + + E V + Y + A S +
Sbjct: 26502 GKPLPKVTLSRDGVPLKATMRFNTEITAE--NLTINLKESVTADAGRYEITAANSSGTTK 26559
Query: 860 ASQPFMPIGPPSEPTH-LAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVA 918
A + + P PT + + D+++ +V+LKW PP+ G + Y + + W
Sbjct: 26560 AFINIVVLDRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTE 26619
Query: 919 ALQGLTEHTSILVKDLPTGARLLFRVRAHNMAG-----PGAPVTTTEPVTVQEILQRPRL 973
+ T + V L TG FR++A N G A VT P T P
Sbjct: 26620 -VSATVARTMMKVMKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTP-- 26676
Query: 974 QLPRHLRQTIQKKVGEPVN------LLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTD 1027
+ R++I EPV+ + + K R + W K ++ IR +
Sbjct: 26677 WVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQK------ANKLVIRTTHFK 26730
Query: 1028 TILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWK 1087
+ I A Y + + +D PP+++R+TD +V+L W+
Sbjct: 26731 -VTTISAGLIYEFRVYAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQ 26789
Query: 1088 PPQDVGNTELWGYTVQKADKKTMEWFTV-LEHYRRTHCVVPELIIGNGYYFRVFSQNMVG 1146
P G +++ GY V++ D W + T ++ L + Y FRVF++N VG
Sbjct: 26790 QPAFDGGSKITGYIVERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVG 26849
Query: 1147 FSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVI---AGYTAMLCCA 1203
+ P+ +D P PL V+ AG + L
Sbjct: 26850 SISNPSEVVGPI--------------TCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAG 26895
Query: 1204 VRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEAR 1263
+ G P P I W+K+ +L +A + + + ++ I+ + G Y + N G A
Sbjct: 26896 ISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRNAMGSAS 26955
Query: 1264 CECRLEV 1270
R+++
Sbjct: 26956 ATIRVQI 26962
Score = 99.4 bits (246), Expect = 2e-20
Identities = 77/249 (30%), Positives = 111/249 (44%), Gaps = 13/249 (5%)
Query: 391 DAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCV---VGGEKCSTEL 447
D E +W KNG +I+ S Y + L I + D A+ + GE S
Sbjct: 2106 DPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAF 2165
Query: 448 FVKEPPVLITRPLEDQLVMVGQR---VEFECEVSEEGAQVKWLKDGVELTREETFKYRFK 504
+ + LIT E Q V+ ++ FECE SE +VKW KDG+E+ E KYR
Sbjct: 2166 LLVQAKQLITFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEV--HEGDKYRMH 2223
Query: 505 KDGQRHHLIINEAMLEDAGHYALC---TSGGQALAELIVQEKKLEVYQSIADLMVGAKDQ 561
D + H L I DA Y+ + A+LIV+ +E + + D+ V
Sbjct: 2224 SDRKVHFLSILTIDTSDAEDYSCVLVEDENVKTTAKLIVEGAVVEFVKELQDIEVPESYS 2283
Query: 562 AVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEG- 620
+C VS EN+ G W N EL + + ++ LT+ DVT D+ +YSFV +G
Sbjct: 2284 GELECIVSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGK 2343
Query: 621 -FACNLSAK 628
C L K
Sbjct: 2344 KTTCKLKMK 2352
Score = 99.0 bits (245), Expect = 3e-20
Identities = 116/522 (22%), Positives = 200/522 (38%), Gaps = 83/522 (15%)
Query: 772 PDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDL-IQELS 830
P P+ PK+++ S ++ W P YDGG P+ GY++E K+ + W +Q
Sbjct: 25003 PGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQ 25062
Query: 831 HEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMP---IGPP-----SEPTHLAVEDVS 882
++ E Y R+ A+N+ G+ P+ + I PP ++ + V S
Sbjct: 25063 FTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRAS 25122
Query: 883 DTT---VSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGAR 939
T V++K RP V +G + A ++ + T +++ ++
Sbjct: 25123 ATLRLFVTIKGRPEPEVKWEKAEGILTDR---------AQIEVTSSFTMLVIDNVTRFDS 25173
Query: 940 LLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQG 999
+ + N +G + T V V+ +L P PVNL I
Sbjct: 25174 GRYNLTLENNSG-----SKTAFVNVR-VLDSP----------------SAPVNLTIREVK 25211
Query: 1000 KPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAA-RRVHSGTYQVTVRIENMED---- 1054
K ++W PL I N + R A + + + T RIEN+++
Sbjct: 25212 KDSVTLSWEP---PLIDGGAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSY 25268
Query: 1055 ----------------KATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELW 1098
+ T ++V + P PP + + D ++W+ P+ G +++
Sbjct: 25269 YFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKIT 25328
Query: 1099 GYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPV 1158
GY V+ K + +W T + + + L G Y FRV + N G SD P
Sbjct: 25329 GYVVEMQTKGSEKWSTCTQ-VKTLEATISGLTAGEEYVFRVAAVNEKGRSD-------PR 25380
Query: 1159 FIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNG 1218
+ P I A D PS P +V A + +G P+ ++W K+G
Sbjct: 25381 QLGVPVI--------ARDIEIKPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDG 25432
Query: 1219 LDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQG 1260
L E R + S + V +L I++ D G Y +N G
Sbjct: 25433 QTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAG 25474
Score = 99.0 bits (245), Expect = 3e-20
Identities = 115/467 (24%), Positives = 176/467 (37%), Gaps = 65/467 (13%)
Query: 824 DLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSD 883
DL L +A R+ G YE+++ NA+G + + Q GPP P + + V+
Sbjct: 26926 DLASILIKDADRLNSGC-YELKLR--NAMGSASATIRVQILDKPGPPGGP--IEFKTVTA 26980
Query: 884 TTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFR 943
++L WRPP G + Y VE W + L E I + G +FR
Sbjct: 26981 EKITLLWRPPADDGGAKITHYIVEKRETSRVVWSMVSEHL-EECIITTTKIIKGNEYIFR 27039
Query: 944 VRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRP 1003
VRA N G G P+ + V + +P + T K
Sbjct: 27040 VRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKIT-----------------KNSM 27082
Query: 1004 QVTWTKE----GQPLAGEEVSIRNSPT--------DTILFIR--AARRVHSGTYQVTVRI 1049
V W++ G ++G + R+ + +TI R + YQ V
Sbjct: 27083 TVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCA 27142
Query: 1050 ENMEDKATL--------VLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYT 1101
N + +D P PP +R+ D+ ++ L W P G + + GY
Sbjct: 27143 VNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYV 27202
Query: 1102 VQKADKKTMEWFTVLE--HYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVF 1159
V+ + EW TV R T VV L G YYFRV + N G EP+
Sbjct: 27203 VEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQG-------EPIE 27255
Query: 1160 IPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVI---AGYTAMLCCAVRGSPKPKISWFK 1216
+ P +A D EAP + R+ + AG + +G P P ++W K
Sbjct: 27256 MNEP--------VQAKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRK 27307
Query: 1217 NGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEAR 1263
+ +LG DAR+ + + L I + D G Y+ N GE +
Sbjct: 27308 DEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPK 27354
Score = 98.6 bits (244), Expect = 3e-20
Identities = 116/522 (22%), Positives = 197/522 (37%), Gaps = 81/522 (15%)
Query: 772 PDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDL-IQELS 830
P P PK+ ++ S + W P YDGG I GYI+E+ W I + +
Sbjct: 22838 PGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTN 22897
Query: 831 HEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PIGPPSEPTHLAVEDVSDTT-- 885
E +++E Y R+ A+N G+ + P + + P L + + +
Sbjct: 22898 IEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAG 22957
Query: 886 ------VSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGAR 939
V +K RP V G +DG + A + + TS+++ ++
Sbjct: 22958 GSLRLFVPIKGRPTPEVKWGKVDGEIRD---------AAIIDVTSSFTSLVLDNVNRYDS 23008
Query: 940 LLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQG 999
+ + N +G T + VTV+ +L P PVNL +
Sbjct: 23009 GKYTLTLENSSG-----TKSAFVTVR-VLDTP----------------SPPVNLKVTEIT 23046
Query: 1000 KPRPQVTWTKE----GQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVT--------- 1046
K +TW G + V R + + + H ++++
Sbjct: 23047 KDSVSITWEPPLLDGGSKIKNYIVEKREATRKS--YAAVVTNCHKNSWKIDQLQEGCSYY 23104
Query: 1047 --VRIEN-----MEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWG 1099
V EN + + ++V + P PP + V D +V+L W P+ G +++
Sbjct: 23105 FRVTAENEYGIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQ 23164
Query: 1100 YTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVF 1159
Y V+ K + +W + + V+ L G Y FRV + N G SD + V
Sbjct: 23165 YIVEMQAKHSEKW-SECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLA---VP 23220
Query: 1160 IPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGL 1219
I + EP P+F+ + SV G + + G PKP I+W K+GL
Sbjct: 23221 IVAKDLVIEP--------DVKPAFS----SYSVQVGQDLKIEVPISGRPKPTITWTKDGL 23268
Query: 1220 DLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGE 1261
L + R + + TL I++ DGG Y N+ G+
Sbjct: 23269 PLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQ 23310
Score = 98.6 bits (244), Expect = 3e-20
Identities = 125/521 (23%), Positives = 208/521 (39%), Gaps = 94/521 (18%)
Query: 736 FTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVI---DVPDAPAAPKISNVGEDSCTVQW 792
F + E+ E + V +N VG + + + D D P P+ V + T+QW
Sbjct: 23482 FKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPPGTPEPIMVKRNEITLQW 23541
Query: 793 EPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAI 852
P YDGG I GYI+E++ RWM+ +F + E + E YE RV A NA
Sbjct: 23542 TKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAA 23601
Query: 853 G-MSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSL--KWRPPERVGAGGLDGYSVEYC 909
G +S+PS ++ P A ++V +S+ K+R V AG + + +E
Sbjct: 23602 GAISKPSDSTGPI-----------TAKDEVELPRISMDPKFRDTIVVNAG--ETFRLEAD 23648
Query: 910 PEG----CSEWVAALQGLTEHTSILVKDLPTGARLLFR-----------VRAHNMAGPGA 954
G EW+ + + E +K+ A L+ + +RA N+AG
Sbjct: 23649 VHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAG--- 23705
Query: 955 PVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVN-LLIPFQGKPRPQVTWTKEGQP 1013
+ + PV V ++L RP G P + + + +TW+ Q
Sbjct: 23706 --SKSFPVNV-KVLDRP----------------GPPEGPVQVTGVTSEKCSLTWSPPLQD 23746
Query: 1014 LAGEEVS---IRNSPTDTILFIRAARRVHSGTYQVTVRIEN------------------M 1052
G ++S + T + + A V + + +VT +E +
Sbjct: 23747 -GGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPL 23805
Query: 1053 EDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEW 1112
E L+ P PP+ L VT+ ++ + W P G +E+ GY V+K D+ + W
Sbjct: 23806 ESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRW 23865
Query: 1113 FTV-LEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTK-----EPVFIPRPGIT 1166
V L + Y FRV ++N G + + T +PVF P P
Sbjct: 23866 IKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGP--- 23922
Query: 1167 YEPPNYKALDFSE---APSFTQPLVN-RSVIAGYTAMLCCA 1203
P N +D ++ ++ +P+ + S I GY +C A
Sbjct: 23923 --PTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEICKA 23961
Score = 98.2 bits (243), Expect = 4e-20
Identities = 195/923 (21%), Positives = 340/923 (36%), Gaps = 157/923 (17%)
Query: 393 EVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQC----VVGGEKCSTELF 448
++ W K+ +EI+ G+ Y + TLT+ + D Y C + G + CS +L
Sbjct: 7242 KITWAKDNREIRPGGN-YKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKDSCSAQLG 7300
Query: 449 VKEPPVLITRPLEDQLVMVGQRVEFECEV-SEEGAQVKWLKDGVELTREETFKYRFKKDG 507
V+EPP I + ++V + +EC++ +V W KD E+ +E+ K+R
Sbjct: 7301 VQEPPRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEI--QESSKFRMSFVD 7358
Query: 508 QRHHLIINEAMLEDAGHYA--LCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAV-F 564
L ++ +ED+G Y + G A + ++ K+ +++ + K V
Sbjct: 7359 SVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKEPPIFRKKPHPIETLKGADVHL 7418
Query: 565 KCEVSDENVRGV-WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFAC 623
+CE+ V W K+ +EL + K+ + + I +V AD +Y C
Sbjct: 7419 ECELQGTPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQ-------C 7471
Query: 624 NLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIW 683
+ + + + + + PP+ ++ D I V G +++L I G +V+W
Sbjct: 7472 KATNDVG-SDTCVGSIALKAPPRF----VKKLSD-ISTVVGKEVQLQTTIEGAEPISVVW 7525
Query: 684 QKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEK 743
K DK + + + +++ + E
Sbjct: 7526 FK----------------------------DKGEIVRESDNIWISYSENIATLQFSRVEP 7557
Query: 744 EDEGVYTVTVKNPVGEDQVNLTVKVID---VPDAPAAPKISNVGEDSCTVQWEPPAYDGG 800
+ G YT +KN G + T+ V++ + + P + K++ D+CT++ G
Sbjct: 7558 ANAGKYTCQIKNDAGMQECFATLSVLEPATIVEKPESIKVTT--GDTCTLE----CTVAG 7611
Query: 801 QPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPA 860
P L S +W + +L + ++ + + +V + I ++
Sbjct: 7612 TPEL----------STKWFKDGKELTSDNKYK-------ISFFNKVSGLKIINVAPSDSG 7654
Query: 861 SQPFMPIGPPSEPTHLAVEDVSDTTV--SLKWRPPERVGAGGLD-----------GYSVE 907
F P + + A VSD TV S + E G G SV
Sbjct: 7655 VYSFEVQNPVGKDSCTASLQVSDRTVPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVS 7714
Query: 908 YCPEG--CSEWVAALQGLTEHT-SILVKDLPTGARLLFRVRAHNMAGP---GAPVTTTEP 961
+ EG S LT++T ++ V L + A NMAG AP+T EP
Sbjct: 7715 WFHEGNEISSGRKYQTTLTDNTCALTVNMLEESDSGDYTCIATNMAGSDECSAPLTVREP 7774
Query: 962 VTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEE--- 1018
+Q+P + G V +G P V+W K L +
Sbjct: 7775 ---PSFVQKP---------DPMDVLTGTNVTFTSIVKGTPPFSVSWFKGSSELVPGDRCN 7822
Query: 1019 VSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTD-- 1076
VS+ +S + LF SG Y T + N KA+ + K R+ D
Sbjct: 7823 VSLEDSVAELELF--DVDTSQSGEY--TCIVSNEAGKASCTTHLYIKAPAKFVKRLNDYS 7878
Query: 1077 -AWGLNVALE----WKPPQDVGNTELWGYTV---QKADKKTMEWFTVLEHYRRTHCVVPE 1128
G + LE PP V + G V Q+ + T E +LE +P
Sbjct: 7879 IEKGKPLILEGTFTGTPPISV-TWKKNGINVTPSQRCNITTTEKSAILE--------IPS 7929
Query: 1129 LIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLV 1188
+ + + + +N G +A + E P F + L
Sbjct: 7930 STVEDAGQYNCYIENASGKDSCSA---------------------QILILEPPYFVKQLE 7968
Query: 1189 NRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDG 1248
V G +A L C + G+P+ +SW+K L ++M + V TL + D
Sbjct: 7969 PVKVSVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATLVFNQVDINDS 8028
Query: 1249 GIYVCRATNLQGEARCECRLEVR 1271
G Y+C+A N GE L V+
Sbjct: 8029 GEYICKAENSVGEVSASTFLTVQ 8051
Score = 97.4 bits (241), Expect = 8e-20
Identities = 105/411 (25%), Positives = 162/411 (39%), Gaps = 57/411 (13%)
Query: 876 LAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLP 935
L V V+ +L W P+ G + Y VE WV ++G S +V L
Sbjct: 29147 LTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLNWVI-VEGECPTLSYVVTRLI 29205
Query: 936 TGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLI 995
+FRVRA N GPG PV + EP+ + P I ++VG
Sbjct: 29206 KNNEYIFRVRAVNKYGPGVPVES-EPIVARNSFTIPS-------PPGIPEEVGT------ 29251
Query: 996 PFQGKPRPQVTWTKE----GQPLAGEEVSIRNSPT--------DTILF---IRAARRVHS 1040
GK + WTK G ++ V R + D +++ ++ +
Sbjct: 29252 ---GKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEG 29308
Query: 1041 GTYQVTVRIENME-----DKATLVLQVVDK---PSPPQDLRVTDAWGLNVALEWKPPQDV 1092
YQ V N +A+ + + P PP RV D +++L W P
Sbjct: 29309 CDYQFRVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYD 29368
Query: 1093 GNTELWGYTVQKADKKTMEWFTVLEH--YRRTHCVVPELIIGNGYYFRVFSQNMVGFSDR 1150
G T++ GY ++ +K T +W+ V + R T VP+L +G Y FRV + N+ G S+
Sbjct: 29369 GGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEY 29428
Query: 1151 AATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKP 1210
+ + E + R I D A + + R AG + L +V G P P
Sbjct: 29429 SESIAEIEPVERIEIP---------DLELADDLKKTVTIR---AGASLRLMVSVSGRPPP 29476
Query: 1211 KISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGE 1261
I+W K G+DL A +L ++ K +D G Y A N G+
Sbjct: 29477 VITWSKQGIDLASRAIIDTTESYSLLIVD--KVNRYDAGKYTIEAENQSGK 29525
Score = 95.5 bits (236), Expect = 3e-19
Identities = 180/840 (21%), Positives = 287/840 (34%), Gaps = 171/840 (20%)
Query: 12 FSKKPRSVEVAAGSPAVFEAE-TERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVRE 70
F KP SV++A G F+ T A +K+ W + +I Y + TLTV +
Sbjct: 7214 FDLKPVSVDLALGESGTFKCHVTGTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVLK 7273
Query: 71 VGPADQGSYAV----IAGSSKVKFDLKVIEAEKAEPMLAPAPAPAEATGAPGEAPAPAA- 125
VG D G Y IAG L V E + L P+ + E +
Sbjct: 7274 VGKGDAGQYTCYASNIAGKDSCSAQLGVQEPPRFIKKLEPSRIVKQDEFTRYECKIGGSP 7333
Query: 126 -----------ELGES------------------------------APSPKGSSSAALNG 144
E+ ES A + GS+S++ +
Sbjct: 7334 EIKVLWYKDETEIQESSKFRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSL 7393
Query: 145 PTPGAPDDPIGLFVMRPQDGEVTVGGSITFSARVAGASLLKPPV-VKWFKGKWVDLSSKV 203
P +F +P E G + + G PP V W+K K
Sbjct: 7394 KVKEPP-----IFRKKPHPIETLKGADVHLECELQGT----PPFHVSWYKDK-------- 7436
Query: 204 GQHLQLHDSYDRASKVYLFELHITDAQPAFTGSYRCEVSTKDKFDCSNFNLTVHEAMGTG 263
+ L+ Y S+ +L +HI + A G Y+C+ T
Sbjct: 7437 -RELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKA--------------------TN 7475
Query: 264 DLDLLSAFRRTSLAGGGRRISDSHEDTGILDFSSLLKKRDSFRTPRDSK--LEAPAEEDV 321
D+ + +L R + + D S+++ K +T + + +D
Sbjct: 7476 DVGSDTCVGSIALKAPPRFVKK------LSDISTVVGKEVQLQTTIEGAEPISVVWFKDK 7529
Query: 322 WEILRQAPP---SEYERIA-FQYGVTDLRGMLKRLKGMRRDEKKSTAFQ--KKLEPAYQV 375
EI+R++ S E IA Q+ + K ++ D F LEPA V
Sbjct: 7530 GEIVRESDNIWISYSENIATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVLEPATIV 7589
Query: 376 SKGHKIRLTVE---------LADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQC 426
K I++T + KW K+G+E+ S +KY L I
Sbjct: 7590 EKPESIKVTTGDTCTLECTVAGTPELSTKWFKDGKELT-SDNKYKISFFNKVSGLKIINV 7648
Query: 427 SLADDAAY----QCVVGGEKCSTELFVKEP--PVLITRPLEDQLVMVGQRVEFECEV-SE 479
+ +D Y Q VG + C+ L V + P TR L++ + G V EC+V
Sbjct: 7649 APSDSGVYSFEVQNPVGKDSCTASLQVSDRTVPPSFTRKLKETNGLSGSSVVMECKVYGS 7708
Query: 480 EGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSG----GQAL 535
V W +G E++ KY+ L +N D+G Y + +
Sbjct: 7709 PPISVSWFHEGNEISSGR--KYQTTLTDNTCALTVNMLEESDSGDYTCIATNMAGSDECS 7766
Query: 536 AELIVQEKKLEVYQ-SIADLMVGAKDQAVFKCEVSDENVRGV-WLKNGKELVPDSRIKVS 593
A L V+E V + D++ G F V V W K ELVP R VS
Sbjct: 7767 APLTVREPPSFVQKPDPMDVLTGTN--VTFTSIVKGTPPFSVSWFKGSSELVPGDRCNVS 7824
Query: 594 HIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLH-FMEVKIDFVPRQEPPKIHLDCP 652
V +L + DV + +Y+ + A S H +++ FV R I
Sbjct: 7825 LEDSVAELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKAPAKFVKRLNDYSIE---- 7880
Query: 653 GRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWV 712
G L L+ +G P +V W+K N P++
Sbjct: 7881 ----------KGKPLILEGTFTGTPPISVTWKK--NGINVTPSQ---------------- 7912
Query: 713 FDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVP 772
R + TT+ +I + + ED G Y ++N G+D + + +++ P
Sbjct: 7913 -----------RCNITTTEKSAILEIPSSTVEDAGQYNCYIENASGKDSCSAQILILEPP 7961
Score = 95.1 bits (235), Expect = 4e-19
Identities = 68/224 (30%), Positives = 97/224 (43%), Gaps = 4/224 (1%)
Query: 391 DAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCSTELFVK 450
+A V W K G +I S K+ + G K L I+ D+ Y V G+K S LFV
Sbjct: 11512 EANVIWSK-GPDIIKSSDKFDIIADGKKHILVINDSQFDDEGVYTAEVEGKKTSARLFVT 11570
Query: 451 EPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKKDGQRH 510
+ PLEDQ V G+ F CE+S E V W K+ +L T +G+ H
Sbjct: 11571 GIRLKFMSPLEDQTVKEGETATFVCELSHEKMHVVWFKNDAKLHTSRTVL--ISSEGKTH 11628
Query: 511 HLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSD 570
L + E L+D + A+L V E + D KD+ KCEVS
Sbjct: 11629 KLEMKEVTLDDISQIKAQVKELSSTAQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVS- 11687
Query: 571 ENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADY 614
++V W K+G+E+VP + + G L I D+ +Y
Sbjct: 11688 KDVPVKWFKDGEEIVPSPKYSIKADGLRRILKIKKADLKDKGEY 11731
Score = 94.4 bits (233), Expect = 6e-19
Identities = 97/413 (23%), Positives = 161/413 (38%), Gaps = 53/413 (12%)
Query: 870 PSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSI 929
P P + +++VS ++++ W PPE G + Y VE + W Q + TSI
Sbjct: 25488 PGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQAVAR-TSI 25546
Query: 930 LVKDLPTGARLLFRVRAHNMAGPGA-----------PVTTTEPVTVQEILQRPRLQLPRH 978
+ L TG+ FRV A N G + P + P +++ + +
Sbjct: 25547 KIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTM--- 25603
Query: 979 LRQTIQKKVGEPVNLLIPF--QGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAAR 1036
T Q V + + +I + + K R + W+K + L + ++ S D L
Sbjct: 25604 -LVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANKILIAD-TQMKVSGLDEGLM----- 25656
Query: 1037 RVHSGTYQVTVRIENME-----DKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQD 1091
Y+ V EN+ K+ + D PP VT+ +V+L+W P
Sbjct: 25657 ------YEYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQPEVTNITRKSVSLKWSKPHY 25710
Query: 1092 VGNTELWGYTVQKADKKTMEWFTV-LEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDR 1150
G ++ GY V++ + W + + T+ V EL Y FRVF++N
Sbjct: 25711 DGGAKITGYIVERRELPDGRWLKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSE 25770
Query: 1151 AATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVI---AGYTAMLCCAVRGS 1207
+ + P+ + D E P + R VI AG + + G
Sbjct: 25771 PSESTGPIIVK--------------DDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGR 25816
Query: 1208 PKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQG 1260
P P ISW K+G+++ E AR + S L ++ D G YV N+ G
Sbjct: 25817 PLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAG 25869
Score = 94.0 bits (232), Expect = 8e-19
Identities = 181/842 (21%), Positives = 305/842 (36%), Gaps = 159/842 (18%)
Query: 3 EPGKKPVSAFSKKPRSVEVAAGSPAVFEAETERAG-VKVRWQRGGSDISASNKYGLATEG 61
EP K P F KP S++V AG A FE A +++ W + +I Y + G
Sbjct: 6266 EPKKSPF--FDIKPVSIDVIAGESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCVG 6323
Query: 62 TRHTLTVREVGPADQGSYAVIAGSSKVKFDLKVIEAEKAEPMLAPAPAPAEATGAPGEAP 121
L + +VG D G Y A ++ V D+ + EP A GE+
Sbjct: 6324 NTPHLRILKVGKGDSGQYTCQA-TNDVGKDMCSAQLSVKEPPKFVKKLEASKVAKQGESI 6382
Query: 122 APAAELGESAPSPKGS-------------------SSAALNGPTPGAPDDPIGLFVMRPQ 162
++ S P K S +S AL + +D G ++
Sbjct: 6383 QLECKISGS-PEIKVSWFRNDSELHESWKYNMSFINSVALLTINEASAEDS-GDYICEAH 6440
Query: 163 DGEVTVGGSITFSARVAGASLLKPPVVKWFKGKWVDLSSKVG-------------QHLQL 209
+G S + + KP V KG V L ++ + ++
Sbjct: 6441 NGVGDASCSTALTVKAPPVFTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRN 6500
Query: 210 HDSYDRASKVYLFELHITDAQPAFTGSYRCEVSTKDKFDCSNFNLTVHEAMGTGDLDLLS 269
+ SK + LHI + + + G Y C+ + + D + ++ E
Sbjct: 6501 SKKFKITSKHFDTSLHILNLEASDVGEYHCKATNEVGSDTCSCSVKFKEPPRFV------ 6554
Query: 270 AFRRTSLAGGGRRISDSHEDTGILDFSSLLKKRDSFRTPRDSKLEAPAEEDVWEILRQAP 329
+++SD+ T I D L + F+ + +D E++R+
Sbjct: 6555 -----------KKLSDT--STLIGDAVELRAIVEGFQP-----ISVVWLKDRGEVIRE-- 6594
Query: 330 PSEYERIAF-------QYGVTDLRGMLKRLKGMRRDE--KKSTAFQKKLEPAYQVSKGHK 380
SE RI+F Q G + K + ++ D ++ +A LEPA + K
Sbjct: 6595 -SENTRISFIDNIATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVLEPARIIEKPEP 6653
Query: 381 IRLT---------VELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADD 431
+ +T V + KW K+G+E+ + SK+ I +L I ++D
Sbjct: 6654 MTVTTGNPFALECVVTGTPELSAKWFKDGRELS-ADSKHHITFINKVASLKIPCAEMSDK 6712
Query: 432 AAYQCVV----GGEKCSTELFVKE---PPVLITRPLEDQLVMVGQRVEFECEVSEEGA-Q 483
Y V G C+ + V + PP I R L+D ++G V EC VS
Sbjct: 6713 GLYSFEVKNSVGKSNCTVSVHVSDRIVPPSFI-RKLKDVNAILGASVVLECRVSGSAPIS 6771
Query: 484 VKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLE--DAGHY----ALCTSGGQALAE 537
V W +DG E+ + F ++ +N ++LE D G Y A + A
Sbjct: 6772 VGWFQDGNEIVSGPKCQSSFSENV----CTLNLSLLEPSDTGIYTCVAANVAGSDECSAV 6827
Query: 538 LIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDENVRGV------WLKNGKELVPDSRIK 591
L VQE ++ D + ++ V +RG W K +ELVP
Sbjct: 6828 LTVQEPPS--FEQTPDSVEVLPGMSLTFTSV----IRGTPPFKVKWFKGSRELVPGESCN 6881
Query: 592 VSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLH-FMEVKIDFVPRQEPPKIHLD 650
+S V +L + +V P + DYS + A + S H F++ FV R
Sbjct: 6882 ISLEDFVTELELFEVQPLESGDYSCLVTNDAGSASCTTHLFVKEPATFVKRLA------- 6934
Query: 651 CPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDE 710
V G+ + L+ +G P +V
Sbjct: 6935 -------DFSVETGSPIVLEATYTGTPPISV----------------------------S 6959
Query: 711 WVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVID 770
W+ D+ L+ ++E R + T+ +I + + ED Y+ ++N G+D V V++
Sbjct: 6960 WIKDEYLISQSE-RCSITMTEKSTILEILESTIEDYAQYSCLIENEAGQDICEALVSVLE 7018
Query: 771 VP 772
P
Sbjct: 7019 PP 7020
Score = 93.2 bits (230), Expect = 1e-18
Identities = 98/428 (22%), Positives = 164/428 (38%), Gaps = 61/428 (14%)
Query: 868 GPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHT 927
GPP+ P + ++V+ +++L W PP+ G ++ Y VE + W + T
Sbjct: 22242 GPPTGPVKM--DEVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTW-QIVSATVART 22298
Query: 928 SILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQ----LPRHLRQTI 983
+I L TG FR+ A N G + + EP Q + P + R ++
Sbjct: 22299 TIKACRLKTGCEYQFRIAAENRYGKSTYLNS-EPTVAQYPFKVPGPPGTPVVTLSSRDSM 22357
Query: 984 QKKVGEPVN------LLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARR 1037
+ + EP++ + + K R + W K + +P F +
Sbjct: 22358 EVQWNEPISDGGSRVIGYHLERKERNSILWVK-----------LNKTPIPQTKF-KTTGL 22405
Query: 1038 VHSGTYQVTVRIENME--------DKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPP 1089
Y+ V EN+ + + D P P+ + VT +V L+WK P
Sbjct: 22406 EEGVEYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAIIVTRN---SVTLQWKKP 22462
Query: 1090 QDVGNTELWGYTVQKADKKTMEWFTV-LEHYRRTHCVVPELIIGNGYYFRVFSQNMVGF- 1147
G +++ GY V+K + W + TH V L+ + Y FRV ++N G
Sbjct: 22463 TYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVF 22522
Query: 1148 -----SDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCC 1202
S A T ++ V PR S P + +V V AG + +
Sbjct: 22523 SEPSESTGAITARDEVDPPR--------------ISMDPKYKDTIV---VHAGESFKVDA 22565
Query: 1203 AVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEA 1262
+ G P P I W K +L AR + S +L ++ D G Y+ +A N+ GE
Sbjct: 22566 DIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGER 22625
Query: 1263 RCECRLEV 1270
++V
Sbjct: 22626 SVTVNVKV 22633
Score = 92.4 bits (228), Expect = 2e-18
Identities = 114/418 (27%), Positives = 156/418 (37%), Gaps = 43/418 (10%)
Query: 870 PSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGC--SEWVAALQGLTEHT 927
P P + ED+ T+V KW PP G + Y++E + SEW+ L H
Sbjct: 14802 PGPPINFVFEDIRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWIVVTSTL-RHC 14860
Query: 928 SILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKV 987
V L G LFRVRA N GPG P + +P+ ++ P K +
Sbjct: 14861 KYSVTKLIEGKEYLFRVRAENRFGPGPPCVS-KPLVAKDPFGPP---------DAPDKPI 14910
Query: 988 GEPV--NLLIPFQGKPR----PQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSG 1041
E V N ++ +P+ P + + E + + S N L +
Sbjct: 14911 VEDVTSNSMLVKWNEPKDNGSPILGYWLEKREVNSTHWSRVNKSLLNALKANVDGLLEGL 14970
Query: 1042 TYQVTVRIENMEDKATL--------VLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVG 1093
TY V EN + P PP RVTD + LEW+PP G
Sbjct: 14971 TYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIP-RVTDTSSTTIELEWEPPAFNG 15029
Query: 1094 NTELWGYTVQKADKKTMEWFTVLEHYRRTH-CVVPELIIGNGYYFRVFSQNMVGFSDRAA 1152
E+ GY V K T EW E + V E+ G Y RV + N G
Sbjct: 15030 GGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGEGPPGE 15089
Query: 1153 TTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKI 1212
T +PV + P EPP + LD S ++AG T + V G P P
Sbjct: 15090 T--QPVTVAEP---QEPPAVE-LDVSVKGGI-------QIMAGKTLRIPAVVTGRPVPTK 15136
Query: 1213 SWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
W K +L +D R + + L I+ D G YV ATN G R+EV
Sbjct: 15137 VWTKEEGELDKD-RVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEV 15193
Score = 92.4 bits (228), Expect = 2e-18
Identities = 101/405 (24%), Positives = 158/405 (39%), Gaps = 35/405 (8%)
Query: 867 IGPPSEPTH-LAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTE 925
+G P PT + ++V+ ++LKW PP+ G + Y +E ++WV + +
Sbjct: 20073 VGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCASAV-Q 20131
Query: 926 HTSILVKDLPTGARLLFRVRAHNMAGPGA-----PVTTTEPVTVQEILQRPRLQLPRH-- 978
T+ V L G FRV A N G G P+ P V + P + RH
Sbjct: 20132 KTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNIVDVRHDS 20191
Query: 979 --LRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQ-PLAGEEVSIRNSPTDTILFIRAA 1035
L T KK G + K R + W + + P+ + + R
Sbjct: 20192 VSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLEYEFRVM 20251
Query: 1036 RRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNT 1095
+G V ++ + + L +D P P+ + +T +V L W P+ G
Sbjct: 20252 AINLAG-----VGKPSLPSEPVVALDPIDPPGKPEVINITRN---SVTLIWTEPKYDGGH 20303
Query: 1096 ELWGYTVQKADKKTMEWFTVLEHYRRTHCV--VPELIIGNGYYFRVFSQNMVGFSDRAAT 1153
+L GY V+K D + W H C V +L+ G Y FR+ ++N G +
Sbjct: 20304 KLTGYIVEKRDLPSKSWMKA-NHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSE 20362
Query: 1154 TKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAML-CCAVRGSPKPKI 1212
+ E + YE P LD P+ L ++ AG T +L ++ G P PK
Sbjct: 20363 STETIICKDE---YEAPTI-VLD----PTIKDGL---TIKAGDTIVLNAISILGKPLPKS 20411
Query: 1213 SWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATN 1257
SW K G D+ ++ S L I+ D G Y ATN
Sbjct: 20412 SWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATN 20456
Score = 92.0 bits (227), Expect = 3e-18
Identities = 101/396 (25%), Positives = 150/396 (37%), Gaps = 54/396 (13%)
Query: 393 EVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCV----VGGEKCSTELF 448
+V W K+ +EI+ SG KY + LT+ + D Y C VG + C+ +L
Sbjct: 8183 KVSWAKDSREIR-SGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLN 8241
Query: 449 VKE---PPVLITRPLEDQLVMVGQRVEFECEVS-EEGAQVKWLKDGVELTREETFKYRFK 504
+KE PP R E G + E V+ + V W K+ +E+ + FK
Sbjct: 8242 IKERLIPPSFTKRLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNIEIQPTSNCEITFK 8301
Query: 505 KDGQRHHLIINEAMLEDAGHYALCTSG--GQAL--AELIVQE-KKLEVY-QSIADLMVGA 558
+ L + +A + DAG Y S G AL + ++++E KK V+ Q + + V
Sbjct: 8302 NNTLV--LQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSE 8359
Query: 559 KDQAVFKCEVS-DENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFV 617
+ C V E +R WLK G+E+ P R S L + DV AD DY
Sbjct: 8360 GEYVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCK 8419
Query: 618 PEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRI-----PDTIVVVAGNKLRLDVP 672
A + + K +V I P P GR+ P +I VV
Sbjct: 8420 ASNVAGSDTTK---SKVTIKDKPAVAPATKKAAVDGRLFFVSEPQSIRVVEKTTATFIAK 8476
Query: 673 ISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKD 732
+ GDP P V W K K GRV + D
Sbjct: 8477 VGGDPIPNVKWTKG----------------------------KWRQLNQGGRVFIHQKGD 8508
Query: 733 RSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKV 768
+ + K D G+Y N GE + N+ ++V
Sbjct: 8509 EAKLEIRDTTKTDSGLYRCVAFNEHGEIESNVNLQV 8544
Score = 91.3 bits (225), Expect = 5e-18
Identities = 65/244 (26%), Positives = 113/244 (46%), Gaps = 6/244 (2%)
Query: 374 QVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAA 433
+V +G ++L V+++ E W+K+GQE+Q S +I L I + D
Sbjct: 2366 KVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHIVID-KQSHMLLIEDMTKEDAGN 2424
Query: 434 YQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVS-EEGAQVKWLKDGVE 492
Y + ST V V + PL+D V+ G + EC+VS + VKW + +
Sbjct: 2425 YSFTIPALGLSTSGRVSVYSVDVITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQ 2484
Query: 493 LTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIA 552
+ ++ + K G + L+IN D G Y L + L V+ K+++ + +
Sbjct: 2485 IKPDDRVQAIVK--GTKQRLVINRTHASDEGPYKLIVGRVETNCNLSVE--KIKIIRGLR 2540
Query: 553 DLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEA 612
DL VF+ E+S + +W KE+ P S+ K+ G+++KLT+ ++ DE
Sbjct: 2541 DLTCTETQNVVFEVELSHSGIDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEG 2600
Query: 613 DYSF 616
Y+F
Sbjct: 2601 KYTF 2604
Score = 91.3 bits (225), Expect = 5e-18
Identities = 107/447 (23%), Positives = 169/447 (37%), Gaps = 74/447 (16%)
Query: 846 VYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYS 905
V A N+ G + + + GPP P ++VS V + W PP G + Y
Sbjct: 24384 VTATNSAGTATENLSVIVLEKPGPPVGPVRF--DEVSADFVVISWEPPAYTGGCQISNYI 24441
Query: 906 VEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQ 965
VE + W + T+I + L TG FR+ A N G AP+ + + V VQ
Sbjct: 24442 VEKRDTTTTTW-HMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKSAPLDS-KAVIVQ 24499
Query: 966 EILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKE----GQPLAGEEVSI 1021
+ P G P + K + V W + G + G +
Sbjct: 24500 YPFKEP----------------GPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQ 24543
Query: 1022 RNSPTDTILFIRAARRVHSGT------------YQVTVRIENME--------DKATLVLQ 1061
+ ++IL+++ + T Y+ V EN+ + +
Sbjct: 24544 KEK--NSILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARD 24601
Query: 1062 VVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTV-LEHYR 1120
D P P+ + +T NV L+WK P G +++ GY V+K D W +
Sbjct: 24602 PCDPPGRPEAIVITRN---NVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVL 24658
Query: 1121 RTHCVVPELIIGNGYYFRVFSQNMVGF------SDRAATTKEPVFIPRPGITYEPPNYKA 1174
T V L+ Y FRV ++N G S A T ++ + P + P YK
Sbjct: 24659 ETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLD---PKYKD 24715
Query: 1175 LDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGED-ARFRMFSKQ 1233
+ V AG T +L +RG P P + W K+G +L E AR + S
Sbjct: 24716 VIV--------------VHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTI 24761
Query: 1234 GVLTLEIRKPCPFDGGIYVCRATNLQG 1260
TL ++ DGG Y+ + +N+ G
Sbjct: 24762 QKTTLVVKDCIRTDGGQYILKLSNVGG 24788
Score = 90.9 bits (224), Expect = 7e-18
Identities = 68/227 (29%), Positives = 112/227 (49%), Gaps = 8/227 (3%)
Query: 386 ELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSL--ADDAAYQCVVGGEKC 443
E+++ D +W G+ ++ S + I ++ G KR LT+ + L A + YQ +
Sbjct: 11419 EISEADIPGQWKLKGELLRPSPTCEI-KAEGGKRFLTLHKVKLDQAGEVLYQAL--NAIT 11475
Query: 444 STELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRF 503
+ L VKE + PL+D V ++ FEC ++ E A V W K G ++ + K+
Sbjct: 11476 TAILTVKEIELDFAVPLKDVTVPERRQARFECVLTRE-ANVIWSK-GPDIIKSSD-KFDI 11532
Query: 504 KKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAV 563
DG++H L+IN++ +D G Y G + A L V +L+ + D V + A
Sbjct: 11533 IADGKKHILVINDSQFDDEGVYTAEVEGKKTSARLFVTGIRLKFMSPLEDQTVKEGETAT 11592
Query: 564 FKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPAD 610
F CE+S E + VW KN +L + +S G+ HKL + +VT D
Sbjct: 11593 FVCELSHEKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDD 11639
Score = 90.5 bits (223), Expect = 9e-18
Identities = 108/430 (25%), Positives = 157/430 (36%), Gaps = 64/430 (14%)
Query: 868 GPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHT 927
GPP P + D+ SL W P G + Y VE C +WV AL +T+ T
Sbjct: 18993 GPPQPP--FDISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTK-T 19049
Query: 928 SILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKV 987
S V L G +FRVRA N G P+T+ P+ + Q
Sbjct: 19050 SCRVGKLIPGQEYIFRVRAENRFGISEPLTS-----------------PKMVAQFPFGVP 19092
Query: 988 GEPVNLLIPFQGKPRPQVTWTKE----GQPLAGEEVSIRNSPTDTILFIRAARR-VHSGT 1042
EP N + K V W + G P+ G I +++L+++A V S
Sbjct: 19093 SEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIG--YLIERKERNSLLWVKANDTLVRSTE 19150
Query: 1043 YQVTVRIENME----------------DKATLVLQVVDKPSPPQDLRVTDAWGLNVALEW 1086
Y +E +E K T + PP V D V+L W
Sbjct: 19151 YPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIW 19210
Query: 1087 KPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNG------YYFRVF 1140
P+ G +++ GY V+ +W + H + E G Y FR
Sbjct: 19211 ARPKHDGGSKIIGYFVEACKLPGDKW---VRCNTAPHQIPQEEYTATGLEEKAQYQFRAI 19267
Query: 1141 SQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAML 1200
++ V S + + +PV I + PP +D S A +V AG L
Sbjct: 19268 ARTAVNISPPSEPS-DPVTILAENV---PPR---IDLSVAMKSLL-----TVKAGTNVCL 19315
Query: 1201 CCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQG 1260
V G P P +SW K+G L +M ++ + TLE+ D G Y A N G
Sbjct: 19316 DATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSG 19375
Query: 1261 EARCECRLEV 1270
+L+V
Sbjct: 19376 SKSATIKLKV 19385
Score = 90.5 bits (223), Expect = 9e-18
Identities = 111/461 (24%), Positives = 182/461 (39%), Gaps = 71/461 (15%)
Query: 727 VETTKDRSIFTVEGAEKEDEGVYTVTVKNPVG---EDQVNLTVKVIDVPDAPAAPKISNV 783
++ TK ++ EG E E + V+ +N VG +V+ D D P P+ +
Sbjct: 24559 IQDTKFKTTGLDEGLEYE----FKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAIVI 24614
Query: 784 GEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYE 843
++ T++W+ PAYDGG I GYI+E+K RWM+ +F + E ++E YE
Sbjct: 24615 TRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGLVEDQRYE 24674
Query: 844 MRVYAVNAIG-MSRPSPASQPFM---PIGPPSEPTHLAVEDV-----SDTTV---SLKWR 891
RV A NA G S PS +S I P+ +DV +T V ++ +
Sbjct: 24675 FRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVHAGETFVLEADIRGK 24734
Query: 892 PPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAG 951
P V DG +E ++ + T+++VKD + ++ N+ G
Sbjct: 24735 PIPDV-VWSKDGKELEETAARME-----IKSTIQKTTLVVKDCIRTDGGQYILKLSNVGG 24788
Query: 952 PGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVN-LLIPFQGKPRPQVTWTKE 1010
T + P+TV ++L RP G P L + + + W
Sbjct: 24789 -----TKSIPITV-KVLDRP----------------GPPEGPLKVTGVTAEKCYLAWNPP 24826
Query: 1011 GQPLAGEEVS---IRNSPTDTILFIRAARRVHSGTYQVTVRI------------------ 1049
Q G +S I T + + + + V + Y+VT +
Sbjct: 24827 LQD-GGANISHYIIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGIG 24885
Query: 1050 ENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKT 1109
E +E P PP V+ ++ + W P D G TE+ GY ++K DK+
Sbjct: 24886 EPLESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEG 24945
Query: 1110 MEWFTV-LEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSD 1149
+ W + V L G+ Y FRV ++N G +
Sbjct: 24946 VRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGE 24986
Score = 90.1 bits (222), Expect = 1e-17
Identities = 197/936 (21%), Positives = 332/936 (35%), Gaps = 181/936 (19%)
Query: 394 VKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQC----VVGGEKCSTELFV 449
++W K +E+ GS YI + + +L + +D Y C V GG +CS LFV
Sbjct: 4237 IRWFKGNKELVSGGSCYITKE-ALESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFV 4295
Query: 450 KEPPVLITRPLEDQLVMVGQRVEFECEVS-EEGAQVKWLKDGVELTREETFKYRFKKDGQ 508
KEP + + QL+ G + C+V+ ++ W + E+ +E+ K+R
Sbjct: 4296 KEPATFVEKLEPSQLLKKGDATQLACKVTGTPPIKITWFANDREI--KESSKHRMSFVES 4353
Query: 509 RHHLIINEAMLEDAGHYALCTSGGQALAE-----LIVQE--------KKLEVYQSIADLM 555
L + + +ED+G Y +C + +A ++ +IV+E K +EV + D+M
Sbjct: 4354 TAVLRLTDVGIEDSGEY-MCEAQNEAGSDHCSSIVIVKESPYFTKEFKPIEVLKEY-DVM 4411
Query: 556 VGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYS 615
+ A+ E++ W K+ L + K + L I AD +Y
Sbjct: 4412 LLAEVAGTPPFEIT-------WFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQ 4464
Query: 616 FVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISG 675
C ++ ++ R+ P I +I T + G + G
Sbjct: 4465 -------CRVTNEVGSSICSARVTLREPPSFIK-----KIESTSSL-RGGTAAFQATLKG 4511
Query: 676 DPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSI 735
TV W K DSDE D + E V S+
Sbjct: 4512 SLPITVTWLK---------------------DSDEITEDDNIRMTFENNVA-------SL 4543
Query: 736 FTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKV------------IDVPDA-PAAPKISN 782
+ + G E + +G Y KN G + + + V IDV PA ++
Sbjct: 4544 Y-LSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKEPATITEEAVSIDVTQGDPATLQVKF 4602
Query: 783 VGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVY 842
G T +W DG + LG K K S D + L + + Y
Sbjct: 4603 SGTKEITAKWFK---DGQELTLG----SKYKISVT------DTVSILKIISTEKKDSGEY 4649
Query: 843 EMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVED-------------VSDTTVSLK 889
V N +G S I PPS L D +S++
Sbjct: 4650 TFEVQ--NDVGRSSCKARINVLDLIIPPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQ 4707
Query: 890 W-RPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHN 948
W + + + A + Y + ++ L+G T + A N
Sbjct: 4708 WFKDDQEISAS--EKYKFSFHDNTAFLEISQLEGTDSGT--------------YTCSATN 4751
Query: 949 MAGPG---APVTTTEPVTVQEILQRPRLQ-LPRHLRQTIQKKVGEPVNLLIPFQGKPRPQ 1004
AG +T EP +++P+ Q + + R ++ VG G
Sbjct: 4752 KAGHNQCSGHLTVKEP---PYFVEKPQSQDVNPNTRVQLKALVG----------GTAPMT 4798
Query: 1005 VTWTKEGQPL-AGEEVSIRNSPTDTILFIRAARRVHSGTY--QVTVRIENMEDKATLVL- 1060
+ W K+ + L +G S+ T T L + AA+ SGTY Q++ + KATL +
Sbjct: 4799 IKWFKDNKELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSKATLFVK 4858
Query: 1061 ---QVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLE 1117
Q + KPSP LR + + P V + L G + K + + L
Sbjct: 4859 EPPQFIKKPSPVLVLRNGQSTTFECQITGTPKIRV-SWYLDGNEITAIQKHGISFIDGLA 4917
Query: 1118 HYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDF 1177
++ + + N + ++N G + + K
Sbjct: 4918 TFQ-----ISGARVENSGTYVCEARNDAGTASCSIELK---------------------V 4951
Query: 1178 SEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLT 1237
E P+F + L V+ L C V G+P +++W KN ++ ++ + + V
Sbjct: 4952 KEPPTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRVSVFN 5011
Query: 1238 LEIRKPCPFDGGIYVCRATNLQGEARCECRLEVRVP 1273
L I K P D G Y C +N G C R+ ++ P
Sbjct: 5012 LHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEP 5047
Score = 89.0 bits (219), Expect = 3e-17
Identities = 135/650 (20%), Positives = 234/650 (36%), Gaps = 98/650 (15%)
Query: 661 VVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPD------------APEDTGDS 708
V A NK + P+ DP V+ Q T + AP P P PE G S
Sbjct: 28126 VSAVNKFGVGRPLDSDP---VVAQIQYTVPD-APGIPEPSNITGNSITLTWARPESDGGS 28181
Query: 709 D--EWVFDKKLLCETEGRVRVETTKDRSI----FTVEGAEKEDEGVYTVTVKNPVGEDQV 762
+ +++ +++ E + V+ R I F V G + +E + V +N G
Sbjct: 28182 EIQQYILERR---EKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVGPA 28238
Query: 763 NLTVKVI------DVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSY 816
+ ++I + P P K+++ + + +++W P +DGG I+GYI+E K
Sbjct: 28239 SGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLG 28298
Query: 817 RWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIG----------MSRPSPASQPFMP 866
W ++N + + + + G Y+ RV A+N G + + P +
Sbjct: 28299 DWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIKAVDRLTAPELD 28358
Query: 867 IGPPSEPTHLAVEDVS---------DTTVSLKWRPPE-----RVGAGGLDGYSVEYCPEG 912
I + TH+ S T + W P+ R D +S E
Sbjct: 28359 IDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADIHTTDSFST-LTVEN 28417
Query: 913 CSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQ--R 970
C+ A LT V++ + F V+ + GP P+T + L
Sbjct: 28418 CNRNDAGKYTLT------VENNSGSKSITFTVKVLDTPGPPGPITFKDVTRGSATLMWDA 28471
Query: 971 PRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTIL 1030
P L + + +K + + +W + + + +
Sbjct: 28472 PLLDGGARIHHYVVEK-------------REASRRSWQVISEKCTRQIFKVNDLAEGVPY 28518
Query: 1031 FIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQ 1090
+ R + Y V E E + ++P+PP+ L V D + L W P
Sbjct: 28519 YFRVSA---VNEYGVGEPYEMPEP-----IVATEQPAPPRRLDVVDTSKSSAVLAWLKPD 28570
Query: 1091 DVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDR 1150
G + + GY ++ K + W H ++ V L+ Y FRV ++N G+S+
Sbjct: 28571 HDGGSRITGYLLEMRQKGSDFWVEA-GHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEP 28629
Query: 1151 AATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKP 1210
V I P I EP ++ T L+ AG + + G P P
Sbjct: 28630 REAFSS-VIIKEPQI--EPT-------ADLTGITNQLITCK--AGSPFTIDVPISGRPAP 28677
Query: 1211 KISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQG 1260
K++W + L E R + + + TL ++ D G Y N G
Sbjct: 28678 KVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAG 28727
Score = 88.2 bits (217), Expect = 5e-17
Identities = 100/421 (23%), Positives = 169/421 (40%), Gaps = 41/421 (9%)
Query: 359 EKKSTAFQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAK 418
E + F+K ++ + K + E+++ D V+W+K+ QE+Q++ I +
Sbjct: 3054 EARHIEFRKHIKDIKVLEK-KRAMFECEVSEPDITVQWMKDDQELQITDRIKIQKEKYVH 3112
Query: 419 RTLTISQCSLADDAAYQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVS 478
R L I ++D Y V GG + +LFV+ V I ++ V+ QR E EV+
Sbjct: 3113 RLL-IPSTRMSDAGKYTVVAGGNVSTAKLFVEGRDVRIRSIKKEVQVIEKQRAVVEFEVN 3171
Query: 479 EEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAEL 538
E+ W KDG+E+ + ++++ + + H + I+E DAG Y ++ L
Sbjct: 3172 EDDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVTL 3231
Query: 539 IVQ-EKKLEVYQSIADLMVGAKDQAVFKCEVSDENVRGV-WLKNGKELVPDSRIKVSHIG 596
V + +V Q + + V + A F +S + W K + L + K H G
Sbjct: 3232 YVNAPEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDG 3291
Query: 597 RVHKLTIDDVTPADEADYSFVPEG--FACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGR 654
+ + L + + P D A Y+ + SA L +EV P QE P
Sbjct: 3292 QEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLS-VEVPEVVSPDQEMPVYPPAIITP 3350
Query: 655 IPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFD 714
+ DT V G R +SG + K D
Sbjct: 3351 LQDT-VTSEGQPARFQCRVSGTDLKVSWYSK----------------------------D 3381
Query: 715 KKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKV-IDVPD 773
KK+ + R+ +D + A EDEG YT N VG QV+ T + ++ P+
Sbjct: 3382 KKI--KPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVG--QVSSTANLSLEAPE 3437
Query: 774 A 774
+
Sbjct: 3438 S 3438
Score = 86.7 bits (213), Expect = 1e-16
Identities = 71/263 (26%), Positives = 119/263 (45%), Gaps = 10/263 (3%)
Query: 375 VSKGHKIRLTVELADHDA-EVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAA 433
V +G K L +++ D VKW N ++I+ G K+ L I++ +D+
Sbjct: 2456 VIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVK-GTKQRLVINRTHASDEGP 2514
Query: 434 YQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVEL 493
Y+ +VG + + L V++ + I R L D Q V FE E+S G V W E+
Sbjct: 2515 YKLIVGRVETNCNLSVEK--IKIIRGLRDLTCTETQNVVFEVELSHSGIDVLWNFKDKEI 2572
Query: 494 TREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIAD 553
+ + KY+ + G+ + L + M +D G Y +L V + + + D
Sbjct: 2573 --KPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTFYAGENMTSGKLTVAGGAIS--KPLTD 2628
Query: 554 LMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEAD 613
V +AVF+CEV++ + +G WL++GK L + I+ G +L I D +
Sbjct: 2629 QTVAESQEAVFECEVANPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGE 2688
Query: 614 YSFVPEGFACNLSAKLHFMEVKI 636
Y++ + SAKL VKI
Sbjct: 2689 YTY--KVATSKTSAKLKVEAVKI 2709
Score = 86.7 bits (213), Expect = 1e-16
Identities = 156/799 (19%), Positives = 296/799 (37%), Gaps = 121/799 (15%)
Query: 1 MPEPGKKPVSAFSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASN--KYGLA 58
+P ++ F K S E+A + V E+ RA +V W + G + + ++ +
Sbjct: 32712 LPVSAPPKITQFLKAEASKEIAKLT-CVVESSVLRAK-EVTWYKDGKKLKENGHFQFHYS 32769
Query: 59 TEGTRHTLTVREVGPADQGSYAVI----AGSSKVKFDLKVIEAEKAEPMLAPAPAPAEAT 114
+GT + L + + +DQG Y G+SK +A
Sbjct: 32770 ADGT-YELKINNLTESDQGEYVCEISGEGGTSKTNLQFM-----------------GQAF 32811
Query: 115 GAPGEAPAPAAELGESAPSPKGSSSAALNGPTPGAPDDPIG---LFVMRPQDGEVTVGGS 171
+ E + +E +S K + S P AP+ PI + V QD V+
Sbjct: 32812 KSIHEKVSKISETKKS--DQKTTESTVTRKTEPKAPE-PISSKPVIVTGLQDTTVSSDSV 32868
Query: 172 ITFSARVAGASLLKPPVVKWFK-GKWVDLSSKVGQHLQLHDSYDRASKVYLFELHITDAQ 230
F+ + G P W K GK + K S D+ + E+H TD
Sbjct: 32869 AKFAVKATGEPR---PTAIWTKDGKAITQGGKYKL------SEDKGG--FFLEIHKTDTS 32917
Query: 231 PAFTGSYRCEVSTKDKFDCSNFNLTVHEAMGTGDLDLLSAFRRTSLAGGGRRISDSHEDT 290
+ G Y C V S+ LT+ +A+ + +S + + + + +
Sbjct: 32918 DS--GLYTCTVKNSAGSVSSSCKLTI-KAIKDTEAQKVSTQKTSEITPQKKAVVQEEISQ 32974
Query: 291 GILDFSSLLKKRDSFRTPRDSKLEAPAEEDVWEILRQAPPSEYERIAFQYGVTDLRGMLK 350
L S +K ++ + + E ++ + E ++++ + E+ +T
Sbjct: 32975 KALR-SEEIKMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEEITKT----- 33028
Query: 351 RLKGMRRDEKKSTAFQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKY 410
+E ++ A K +++G ++ L +A +VKW+ NG E+ S +Y
Sbjct: 33029 ---SQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAGA-TDVKWVLNGVELTNS-EEY 33083
Query: 411 IFESIGAKRTLTISQCSLADDAAYQCV----VGGEKCSTELF----VKEPPVLITRPLED 462
+ G+ +TLTI Q S D+ C+ G KC +L + + P I++P
Sbjct: 33084 RYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTLSKELSDAPAFISQP-RS 33142
Query: 463 QLVMVGQRVEFECEVS-EEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLED 521
Q + GQ V F CE+S E +++W K+ + ++ + + L I A + D
Sbjct: 33143 QNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVS--ISRSRNVYSLEIRNASVSD 33200
Query: 522 AGHYAL--------CTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDENV 573
+G Y + C++ + +V+E EV ++ + S ++V
Sbjct: 33201 SGKYTIKAKNFRGQCSATASLMVLPLVEEPSREV-------VLRTSGDTSLQGSFSSQSV 33253
Query: 574 RGVWLKNGKELVPDSRIKVSHIGRVH--KLTIDDVTPADEADYSFVPEGF--ACNLSAKL 629
+ K S S + + ++ ++ E+ F N++
Sbjct: 33254 QMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQLE 33313
Query: 630 HFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQ 689
+ R PPKI +P I + G L + +G+P P V W
Sbjct: 33314 SSTSKMLKAGIRGIPPKIE-----ALPSDISIDEGKVLTVACAFTGEPTPEVTWSCG--- 33365
Query: 690 GNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVY 749
+K+ + +GR +E T D + + +K+D G+Y
Sbjct: 33366 ------------------------GRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLY 33401
Query: 750 TVTVKNPVGEDQVNLTVKV 768
T+++ N G D + + +
Sbjct: 33402 TLSLGNEFGSDSATVNIHI 33420
Score = 86.3 bits (212), Expect = 2e-16
Identities = 67/265 (25%), Positives = 115/265 (43%), Gaps = 6/265 (2%)
Query: 375 VSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAY 434
V +G EL+ V W KN ++ S + + S G L + + +L D +
Sbjct: 11585 VKEGETATFVCELSHEKMHVVWFKNDAKLHTSRT-VLISSEGKTHKLEMKEVTLDDISQI 11643
Query: 435 QCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELT 494
+ V + +L V E T L D+ + + +CEVS++ VKW KDG E+
Sbjct: 11644 KAQVKELSSTAQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVSKD-VPVKWFKDGEEIV 11702
Query: 495 REETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADL 554
KY K DG R L I +A L+D G Y + A + V+ + ++V + + +
Sbjct: 11703 PSP--KYSIKADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIKVEKPLYGV 11760
Query: 555 MVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADY 614
V + A F+ E+S+ +V G W G+ L ++ G+ H L + + +
Sbjct: 11761 EVFVGETAHFEIELSEPDVHGQWKLKGQPLTASPDCEIIEDGKKHILILHNCQLGMTGEV 11820
Query: 615 SFVPEGFACNLSAKLHFMEVKIDFV 639
SF + +A L E+ + F+
Sbjct: 11821 SF--QAANAKSAANLKVKELPLIFI 11843
Score = 85.9 bits (211), Expect = 2e-16
Identities = 99/420 (23%), Positives = 160/420 (38%), Gaps = 56/420 (13%)
Query: 360 KKSTAFQKKLEPAYQVSKGHKIRLTVELADHDA-EVKWLKNGQEIQMSGSKYIFESIGAK 418
K+ F ++L+P +V K + L E+ EV WLKN +EI+ S KY +
Sbjct: 4952 KEPPTFIRELKPV-EVVKYSDVELECEVTGTPPFEVTWLKNNREIR-SSKKYTLTDRVSV 5009
Query: 419 RTLTISQCSLADDAAYQCVVGGE----KCSTELFVKEPPVLITRPLEDQLVMVGQRVEFE 474
L I++C +D YQC+V E CST + +KEPP I + +E+ ++ F+
Sbjct: 5010 FNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEPPSFIKK-IENTTTVLKSSATFQ 5068
Query: 475 CEVS-EEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHY---ALCTS 530
V+ + WLKD L ++ F L I +G Y A S
Sbjct: 5069 STVAGSPPISITWLKDDQILDEDDNVYISFVDSVAT--LQIRSVDNGHSGRYTCQAKNES 5126
Query: 531 GGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDE-NVRGVWLKNGKELVPDSR 589
G + ++ ++ ++ + + V KD +C V+ ++ WLK+GK++VP
Sbjct: 5127 GVERCYAFLLVQEPAQIVEKAKSVDVTEKDPMTLECVVAGTPELKVKWLKDGKQIVPSRY 5186
Query: 590 IKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHL 649
+S V I V D Y+F E + S + + + P +
Sbjct: 5187 FSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLDQNIPPSFTKKLTKM 5246
Query: 650 DCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSD 709
D V G+ + ++ +SG + W K D E
Sbjct: 5247 D----------KVLGSSIHMECKVSGSLPISAQWFK--------------DGKE------ 5276
Query: 710 EWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVN--LTVK 767
T + R+ + V E ED YT V N G+D + LTVK
Sbjct: 5277 ---------ISTSAKYRLVCHERSVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVK 5327
Score = 85.9 bits (211), Expect = 2e-16
Identities = 103/436 (23%), Positives = 166/436 (38%), Gaps = 67/436 (15%)
Query: 360 KKSTAFQKKLEPAYQVSKGHKIRLTVELADHDA-EVKWLKNGQEIQMSGSKYIFESIGAK 418
K+ F+KK P + KG + L EL V W K+ +E++ SG KY S
Sbjct: 7396 KEPPIFRKKPHPI-ETLKGADVHLECELQGTPPFHVSWYKDKRELR-SGKKYKIMSENFL 7453
Query: 419 RTLTISQCSLADDAAYQCV----VGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFE 474
++ I AD YQC VG + C + +K PP + + L D +VG+ V+ +
Sbjct: 7454 TSIHILNVDAADIGEYQCKATNDVGSDTCVGSIALKAPPRFVKK-LSDISTVVGKEVQLQ 7512
Query: 475 CEVSEEGAQ---VKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSG 531
+ EGA+ V W KD E+ RE + + L + +AG Y
Sbjct: 7513 TTI--EGAEPISVVWFKDKGEIVRESDNIWISYSENIAT-LQFSRVEPANAGKYTCQIKN 7569
Query: 532 GQALAELIVQEKKLE---VYQSIADLMVGAKDQAVFKCEVSDE-NVRGVWLKNGKELVPD 587
+ E LE + + + V D +C V+ + W K+GKEL D
Sbjct: 7570 DAGMQECFATLSVLEPATIVEKPESIKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSD 7629
Query: 588 SRIKVSHIGRVHKLTIDDVTPADEADYSFVPEG----FACNLSAKLHFMEVKIDFVPRQE 643
++ K+S +V L I +V P+D YSF + +C S ++ V F + +
Sbjct: 7630 NKYKISFFNKVSGLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRTVPPSFTRKLK 7689
Query: 644 PPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPE 703
++G+ + ++ + G P +V W +GN+
Sbjct: 7690 ETN--------------GLSGSSVVMECKVYGSPPISVSW---FHEGNEI---------- 7722
Query: 704 DTGDSDEWVFDKKLLCETEGRVRVETTKDRS-IFTVEGAEKEDEGVYTVTVKNPVGEDQV 762
+ GR T D + TV E+ D G YT N G D+
Sbjct: 7723 -----------------SSGRKYQTTLTDNTCALTVNMLEESDSGDYTCIATNMAGSDEC 7765
Query: 763 NLTVKVIDVPDAPAAP 778
+ + V + P P
Sbjct: 7766 SAPLTVREPPSFVQKP 7781
Score = 85.9 bits (211), Expect = 2e-16
Identities = 106/418 (25%), Positives = 147/418 (35%), Gaps = 55/418 (13%)
Query: 868 GPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHT 927
GPP+ P + ++VS V+ W PPE G + Y VE + WV L T
Sbjct: 21160 GPPTGP--IKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVE-LATTVIRT 21216
Query: 928 SILVKDLPTGARLLFRVRAHNMAGPGAPVTTT-----EPVTVQEILQRPRLQLPRHLRQT 982
+ L TG FRV+A N G G +T+ P V P++ T
Sbjct: 21217 TYKATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMT 21276
Query: 983 IQ-----KKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARR 1037
I G P+ L + K R + W + L + + TD I
Sbjct: 21277 ISWHEPLSDGGSPI-LGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGI-------- 21327
Query: 1038 VHSGTYQVTVRIENMEDKAT--------LVLQVVDKPSPPQDLRVTDAWGLNVALEWKPP 1089
Y+ V ENM K+ L L +D P P L +T V L+W P
Sbjct: 21328 ----AYEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRH---TVTLKWAKP 21380
Query: 1090 QDVGNTELWGYTVQKADKKTMEWFTV-LEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFS 1148
+ G ++ Y V+K D W + V L Y FRV ++N
Sbjct: 21381 EYTGGFKITSYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKN----- 21435
Query: 1149 DRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVI---AGYTAMLCCAVR 1205
AA P P IT D EAP + + + AG L V
Sbjct: 21436 --AAGAISPPSEPSDAITCR-------DDVEAPKIKVDVKFKDTVILKAGEAFRLEADVS 21486
Query: 1206 GSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEAR 1263
G P P + W K+G +L A+ + L + D G Y ATN G A+
Sbjct: 21487 GRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGGFAK 21544
Score = 85.9 bits (211), Expect = 2e-16
Identities = 99/432 (22%), Positives = 160/432 (37%), Gaps = 45/432 (10%)
Query: 846 VYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYS 905
+ N +G S PP P +DVS +++L W PP G + Y
Sbjct: 23302 ITVANVVGQKTASIEIVTLDKPDPPKGPVKF--DDVSAESITLSWNPPLYTGGCQITNYI 23359
Query: 906 VEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQ 965
V+ + W + T++ V L TG FR+ A N G + + +P+ Q
Sbjct: 23360 VQKRDTTTTVW-DVVSATVARTTLKVTKLKTGTEYQFRIFAENRYGQSFALES-DPIVAQ 23417
Query: 966 EILQRPRLQ----LPRHLRQTIQKKVGEPVN------LLIPFQGKPRPQVTWTKEGQPLA 1015
+ P + ++ + EPVN + + K R + WTK + +
Sbjct: 23418 YPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKTII 23477
Query: 1016 GEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVT 1075
+ + + I + RV++ V V + + + D P P+ + V
Sbjct: 23478 HDTQFKAQNLEEGIEY---EFRVYAENI-VGVGKASKNSECYVARDPCDPPGTPEPIMVK 23533
Query: 1076 DAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTV-LEHYRRTHCVVPELIIGNG 1134
+ L+W P G + + GY V+K D W + T V L
Sbjct: 23534 RN---EITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQR 23590
Query: 1135 YYFRVFSQNMVGFSDRAA------TTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLV 1188
Y FRV ++N G + + T K+ V +PR S P F +V
Sbjct: 23591 YEFRVIAKNAAGAISKPSDSTGPITAKDEVELPR--------------ISMDPKFRDTIV 23636
Query: 1189 NRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDG 1248
V AG T L V G P P I W + ++ E AR + + L ++ DG
Sbjct: 23637 ---VNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDG 23693
Query: 1249 GIYVCRATNLQG 1260
G Y+ RA+N+ G
Sbjct: 23694 GQYILRASNVAG 23705
Score = 85.5 bits (210), Expect = 3e-16
Identities = 109/404 (26%), Positives = 150/404 (37%), Gaps = 61/404 (15%)
Query: 847 YAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSV 906
Y V A + A + P +L + DVS ++ W PPE G + Y +
Sbjct: 18274 YVVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYIL 18333
Query: 907 EYCPEGCSEWVA-ALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQ 965
E C W + LT T+ V L G +FRVRA N G G P T ++PV
Sbjct: 18334 EKCETKRMVWSTYSATVLTPGTT--VTRLIEGNEYIFRVRAENKIGTGPP-TESKPV--- 18387
Query: 966 EILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKE----GQPLAG----- 1016
+ +T K G P + K V W G+ + G
Sbjct: 18388 -------------IAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLEK 18434
Query: 1017 -EEVSIRNSPTDTILFIRAARRVHS----GTYQVTVRIEN--------MEDKATLVLQVV 1063
E+ S R P + +V + YQ V+ EN + + + +
Sbjct: 18435 KEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPI 18494
Query: 1064 DKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQK----ADKKTMEWF---TVL 1116
+ P PP + RV D ++ L W P G + GY V+ AD E +
Sbjct: 18495 EPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAA 18554
Query: 1117 EHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALD 1176
R V L Y FRV +QN VG R A KE + +P EPP LD
Sbjct: 18555 AQLVRKEFTVTSLDENQEYEFRVCAQNQVGIG-RPAELKEAI---KPKEILEPPEID-LD 18609
Query: 1177 FSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLD 1220
S + LV V AG L VRG P PK++W K G+D
Sbjct: 18610 AS-----MRKLV--IVRAGCPIRLFAIVRGRPAPKVTWRKVGID 18646
Score = 85.5 bits (210), Expect = 3e-16
Identities = 110/462 (23%), Positives = 181/462 (39%), Gaps = 59/462 (12%)
Query: 769 IDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQE 828
+D D P P N+ + T++W P Y GG I YI+E++ + RW++ NF I E
Sbjct: 21354 LDPIDPPGKPVPLNITRHTVTLKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILE 21413
Query: 829 LSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSL 888
+ E YE RV A NA G P + E + V+ TV L
Sbjct: 21414 NEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVIL 21473
Query: 889 KWRPPERVGA--GGLDGYSVEYCPEGCS-EWVAALQGLTE--HTSILVKDL--------- 934
K R+ A G ++E+ +G E A L+ T+++ KD
Sbjct: 21474 KAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYT 21533
Query: 935 -----PTG-ARLLFRVRAHNMAG-PGAPVTTTEPVTVQEILQ-RPRLQLPRHLRQTIQKK 986
P G A+ +F V+ + G P P+ TE + + +L P L
Sbjct: 21534 LTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFPPLD-----------D 21582
Query: 987 VGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRN--SPTDTILFIRAARRVHSGTYQ 1044
G ++ I Q + ++ WT + ++ + + I + A + G
Sbjct: 21583 GGAKIDHYI-VQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYGVG--- 21638
Query: 1045 VTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQK 1104
E +E + L + P PP++ VT ++ + W P G +E+ Y V++
Sbjct: 21639 -----EPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVER 21693
Query: 1105 ADKKTMEWFTV-LEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTK-----EPV 1158
DK W + V L G+ Y FR+ ++N G S + T+ + V
Sbjct: 21694 RDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTV 21753
Query: 1159 FIPRPGITYEPPNYKALDFSEAP---SFTQPLVN-RSVIAGY 1196
F P P P N + LD S + ++ +P+ + S I GY
Sbjct: 21754 FKPGP-----PGNPRVLDTSRSSISIAWNKPIYDGGSEITGY 21790
Score = 85.5 bits (210), Expect = 3e-16
Identities = 66/214 (30%), Positives = 97/214 (45%), Gaps = 18/214 (8%)
Query: 1064 DKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVL-EHYRRT 1122
+KP P +T + + WKPP G ++ Y ++K +KK +W +V E R T
Sbjct: 30823 EKPGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRET 30882
Query: 1123 HCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPS 1182
V LI G Y FRV +N+ G S+ + + EP+ P+ + + P++K
Sbjct: 30883 VFSVKNLIEGLEYEFRVKCENLGGESEWSEIS-EPI-TPKSDVPIQAPHFK--------- 30931
Query: 1183 FTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDA---RFRMFSKQGVLTLE 1239
+ L N +V A L C V G PKP + W++ G ++ D R + F K G L
Sbjct: 30932 --EELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEF-KGGYHQLI 30988
Query: 1240 IRKPCPFDGGIYVCRATNLQGEARCECRLEVRVP 1273
I D +Y RATN G LEV VP
Sbjct: 30989 IASVTDDDATVYQVRATNQGGSVSGTASLEVEVP 31022
Score = 83.2 bits (204), Expect = 1e-15
Identities = 264/1332 (19%), Positives = 454/1332 (34%), Gaps = 185/1332 (13%)
Query: 11 AFSKKPRSVEVAAGSPAVFEAETERAG-VKVRWQRGGSDISASNKYGLATEGTRHTLTVR 69
+F KP S +V GS ++ + + + +RW +G ++ + + E +L +
Sbjct: 4207 SFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGNKELVSGGSCYITKEALESSLELY 4266
Query: 70 EVGPADQGSYAV----IAGSSKVKFDLKVIE----AEKAEP--MLAPAPAPAEATGAPGE 119
V +D G+Y +AG + +L V E EK EP +L A A G
Sbjct: 4267 LVKTSDSGTYTCKVSNVAGGVECSANLFVKEPATFVEKLEPSQLLKKGDATQLACKVTGT 4326
Query: 120 AP------APAAELGESAPSPKG--SSSAALNGPTPGAPDDPIGLFVMRPQDGE------ 165
P A E+ ES+ S+A L G D + + + G
Sbjct: 4327 PPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSI 4386
Query: 166 VTVGGSITFSARVAGASLLK-------------PPV-VKWFKGKWVDLSSKVGQHLQLHD 211
V V S F+ +LK PP + WFK + S +
Sbjct: 4387 VIVKESPYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKDNTILRSGR--------- 4437
Query: 212 SYDRASKVYLFELHITDAQPAFTGSYRCEVSTKDKFDCSNFNLTVHEAMGTGDLDLLSAF 271
Y + +L L I A G Y+C V+ + + +T+ E +
Sbjct: 4438 KYKTFIQDHLVSLQILKFVAADAGEYQCRVTNEVGSSICSARVTLREPP-----SFIKKI 4492
Query: 272 RRTSLAGGGRRISDSHEDTGILDFSSLLKKRDSFRTPRDSKLEAPAEEDVWEILRQAPPS 331
TS GG + + + LK DS D + E +V +
Sbjct: 4493 ESTSSLRGGTAAFQATLKGSLPITVTWLK--DSDEITEDDNIRMTFENNVASLYLSGIEV 4550
Query: 332 EYERIAFQYGVTDLRGMLKRLKGMRRDEKKSTAFQKKLEPAYQVSKGHKIRLTVELA-DH 390
+++ D ++R + ++ +T ++ + + V++G L V+ +
Sbjct: 4551 KHDGKYVCQAKND--AGIQRCSALLSVKEPATITEEAV--SIDVTQGDPATLQVKFSGTK 4606
Query: 391 DAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAY----QCVVGGEKCSTE 446
+ KW K+GQE+ + GSKY L I D Y Q VG C
Sbjct: 4607 EITAKWFKDGQELTL-GSKYKISVTDTVSILKIISTEKKDSGEYTFEVQNDVGRSSCKAR 4665
Query: 447 LFVKE--PPVLITRPLEDQLVMVGQRVEFECEVS-EEGAQVKWLKDGVELTREETFKYRF 503
+ V + P T+ L+ + G ++ EC V+ ++W KD E++ E KY+F
Sbjct: 4666 INVLDLIIPPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASE--KYKF 4723
Query: 504 KKDGQRHHLIINEAMLEDAGHYALCTSG----GQALAELIVQEKKLEVYQSIADLMVGAK 559
L I++ D+G Y + Q L V+E V + V
Sbjct: 4724 SFHDNTAFLEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVKEPPYFV-EKPQSQDVNPN 4782
Query: 560 DQAVFKCEVSDENVRGV-WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVP 618
+ K V + W K+ KEL H G + DD + + E +
Sbjct: 4783 TRVQLKALVGGTAPMTIKWFKDNKEL---------HSGAARSVWKDDTSTSLELFAAKAT 4833
Query: 619 EG--FACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGD 676
+ + C LS + K ++ P I P +V+ G + I+G
Sbjct: 4834 DSGTYICQLSNDVGTATSKATLFVKEPPQFIKKPSP-----VLVLRNGQSTTFECQITGT 4888
Query: 677 PAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIF 736
P V W GN+ A K + +G + F
Sbjct: 4889 PKIRVSW---YLDGNEITA-----------------IQKHGISFIDG---------LATF 4919
Query: 737 TVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVP------DAPAAPKISNVGEDSCTV 790
+ GA E+ G Y +N G ++ +KV + P K S+V E C V
Sbjct: 4920 QISGARVENSGTYVCEARNDAGTASCSIELKVKEPPTFIRELKPVEVVKYSDV-ELECEV 4978
Query: 791 QWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVN 850
PP + ++ ++ +S + L D + + + E + N
Sbjct: 4979 TGTPPFE------VTWLKNNREIRSSKKYTLT-DRVSVFNLHITKCDPSDTGEYQCIVSN 5031
Query: 851 AIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCP 910
G S PPS ++ + +TT LK + G S+
Sbjct: 5032 EGG---SCSCSTRVALKEPPS-----FIKKIENTTTVLKSSATFQSTVAGSPPISI---- 5079
Query: 911 EGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAG----PGAPVTTTEPVTVQE 966
W+ Q L E ++ + + + A L R + +G + E
Sbjct: 5080 ----TWLKDDQILDEDDNVYISFVDSVATLQIRSVDNGHSGRYTCQAKNESGVERCYAFL 5135
Query: 967 ILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPT 1026
++Q P + + + +K +P+ L G P +V W K+G+ + +
Sbjct: 5136 LVQEPAQIVEKAKSVDVTEK--DPMTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFEN 5193
Query: 1027 DTILF-IRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPP----QDLRVTDAWGLN 1081
+ F I++ + SG Y V + L+V+D+ PP + ++ G +
Sbjct: 5194 NVASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLDQNIPPSFTKKLTKMDKVLGSS 5253
Query: 1082 VALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFS 1141
+ +E K + + W + T + ++ H R V L + + +
Sbjct: 5254 IHMECKVSGSLPISAQW--FKDGKEISTSAKYRLVCHERSVSLEVNNLELEDTANYTCKV 5311
Query: 1142 QNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLC 1201
N+ G D A + GI L E PSF + I T
Sbjct: 5312 SNVAG--DDACS----------GI---------LTVKEPPSFLVKPGRQQAIPDSTVEFK 5350
Query: 1202 CAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGE 1261
++G+P KI WFK+ ++L + + + L + G Y C TN G
Sbjct: 5351 AILKGTPPFKIKWFKDDVELVSGPKCFIGLEGSTSFLNLYSVDASKTGQYTCHVTNDVGS 5410
Query: 1262 ARCECRLEVRVP 1273
C L V P
Sbjct: 5411 DSCTTMLLVTEP 5422
Score = 82.0 bits (201), Expect = 3e-15
Identities = 140/673 (20%), Positives = 242/673 (35%), Gaps = 83/673 (12%)
Query: 24 GSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYAVIA 83
G PA F+ +KV W I S + + + L + E P D+G+Y +A
Sbjct: 3359 GQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVA 3418
Query: 84 GSSKVKFDLKVIEAEKAEPMLAPAPAPAEATGAPGEAPAPAAELGESAPSPKGSSSAALN 143
++ + + + + AP E E AA + + P
Sbjct: 3419 SNA-----VGQVSSTANLSLEAPESILHERIEQEIEMEMKAAPVIKRKIEPL-------- 3465
Query: 144 GPTPGAPDDPIGLFVMRPQDGEVTVGGSITFSARVAGASLLKPPVVKWFKGKWVDLSSKV 203
EV +G F+ + A ++ +WFK
Sbjct: 3466 ---------------------EVALGHLAKFTCEIQSAPNVR---FQWFKA--------- 3492
Query: 204 GQHLQLHDSYDRASKVYLFELHITDAQPAFTGSYRCEVSTKDKFDCSNFNLTVHEAMGTG 263
G+ + D S Y+ L I Q G Y C+ S + LTV EA
Sbjct: 3493 GREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEAYPPT 3552
Query: 264 DLDLLSAFRRTSLAGGGRRISDSHEDTGILDFSSLLKKRDSFRTPRDSKLEAPAEEDVWE 323
L + T+ G + + T +++ ++ +K + +P + + AE
Sbjct: 3553 FLSRPKSL--TTFVGKAAKFICTVTGTPVIE--TIWQKDGAALSPSPNWRISDAENK--H 3606
Query: 324 ILRQAPPSEYERIAFQYGVTDLRGMLKRLKGMRRDEKKSTAFQKKLEPAYQVSKGHKIRL 383
IL + + +R + ++ G + +K F K+LEP Q + K+ L
Sbjct: 3607 ILELSNLTIQDRGVYSCKASNKFGADICQAELIIIDKPH--FIKELEPV-QSAINKKVHL 3663
Query: 384 TVEL-ADHDAEVKWLKNGQEIQMSGS-KYIFESIGAKRTLTISQCSLADDAAYQCVV--- 438
++ D V W K+GQ++ K FE A TL I L D Y C
Sbjct: 3664 ECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKIA--TLEIPLAKLKDSGTYVCTASNE 3721
Query: 439 -GGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGA-QVKWLKDGVELTRE 496
G CS + V+EPP + + L++ G+ C++ QV W K+ EL+
Sbjct: 3722 AGSSSCSATVTVREPPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTWFKNNKELSES 3781
Query: 497 ETFKYRFKKDGQRHHLIINEAMLEDAGHY---ALCTSGGQALAELIVQEKKLEVYQSIAD 553
T + F L I + +ED+G Y A+ G + + IV ++ +++
Sbjct: 3782 NTVRMYFV--NSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKEPPSFIKTLEP 3839
Query: 554 LMVGAKDQAVFKCEVSDENVRGV-WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEA 612
+ A+ +CEVS + W K+ K++ + ++ + L I AD
Sbjct: 3840 ADIVRGTNALLQCEVSGTGPFEISWFKDKKQIRSSKKYRLFSQKSLVCLEIFSFNSADVG 3899
Query: 613 DYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVP 672
+Y V N K M + +EPP + D ++ + G + L
Sbjct: 3900 EYECV----VANEVGKCGCMATHL----LKEPPTF-----VKKVDDLIALGGQTVTLQAA 3946
Query: 673 ISGDPAPTVIWQK 685
+ G +V W K
Sbjct: 3947 VRGSEPISVTWMK 3959
Score = 82.0 bits (201), Expect = 3e-15
Identities = 91/374 (24%), Positives = 142/374 (37%), Gaps = 41/374 (10%)
Query: 868 GPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHT 927
GPP+ P + ++++ T++++ W PPE G L GY VE W+ + +T T
Sbjct: 29833 GPPTGP--IKIDEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRST 29890
Query: 928 SILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKV 987
+ L G +FRV A N G G+ + + V E R+ P Q
Sbjct: 29891 FKFTR-LTEGNEYVFRVAATNRFGIGSYLQSE----VIECRSSIRIPGPPETLQIFDVSR 29945
Query: 988 GEPVNLLIPFQGKPRPQVTW--TKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQV 1045
P + QVT + + A V + P T+ R+ Y+
Sbjct: 29946 DGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPV-TMTRYRSTGLTEGLEYEH 30004
Query: 1046 TVRIENME--------DKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTEL 1097
V N K + + + P PQ+ RVTD +V+L W P+D G +++
Sbjct: 30005 RVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKV 30064
Query: 1098 WGYTVQKADKKTMEWF------TVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRA 1151
GY ++ EW T + Y TH +P+ G Y FRV + N G
Sbjct: 30065 TGYLIEMQKVDQHEWTKCNTTPTKIREYTLTH--LPQ---GAEYRFRVLACNAGG----- 30114
Query: 1152 ATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPK 1211
EP +P E Y + E + + + R G L ++G P P
Sbjct: 30115 --PGEPAEVPGTVKVTEMLEYPDYELDER--YQEGIFVRQ---GGVIRLTIPIKGKPFPI 30167
Query: 1212 ISWFKNGLDLGEDA 1225
W K G D+ + A
Sbjct: 30168 CKWTKEGQDISKRA 30181
Score = 81.3 bits (199), Expect = 6e-15
Identities = 100/418 (23%), Positives = 150/418 (35%), Gaps = 61/418 (14%)
Query: 870 PSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSI 929
P P + + +VS +L W PP G + Y +E W + + +
Sbjct: 20473 PGPPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHV 20532
Query: 930 LVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGE 989
K L G +FRV A N G G PV + EPV + + P G
Sbjct: 20533 ATK-LIQGNEYIFRVSAVNHYGKGEPVQS-EPVKMVDRFGPP----------------GP 20574
Query: 990 PVNLLIPFQGKPRPQVTWTKE----GQPLAGEEVSIRNSPTDTILFIRAARRVHS----- 1040
P + K V+W + G + G V R + + ++RA + S
Sbjct: 20575 PEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKS--LRWVRAIKTPVSDLRCK 20632
Query: 1041 -------GTYQVTVRIENME--------DKATLVLQVVDKPSPPQDLRVTDAWGLNVALE 1085
TY+ V EN + L+ P PP + VTD + +L
Sbjct: 20633 VTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLA 20692
Query: 1086 WKPPQDVGNTELWGYTVQKADKKTMEWF--TVLEHYRRTHCVVPELIIGNGYYFRVFSQN 1143
W P G E+ GY V+ W T R T VVP+L Y FR+ + N
Sbjct: 20693 WGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAIN 20752
Query: 1144 MVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCA 1203
G EP IP I A DF + LV R AG + +
Sbjct: 20753 DAGVG-------EPAVIPDVEIVERE---MAPDFELDAELRRTLVVR---AGLSIRIFVP 20799
Query: 1204 VRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGE 1261
++G P P+++W K+ ++L A + + L I + +D G +V N G+
Sbjct: 20800 IKGRPAPEVTWTKDNINLKNRANIE--NTESFTLLIIPECNRYDTGKFVMTIENPAGK 20855
Score = 79.3 bits (194), Expect = 2e-14
Identities = 165/758 (21%), Positives = 271/758 (35%), Gaps = 127/758 (16%)
Query: 360 KKSTAFQKKLEPAYQVSKGHKIRLTVELADHDA-EVKWLKNGQEIQMSGSKYIFESIGAK 418
K F K+L Y + KG + L V W KNG + S + +
Sbjct: 7865 KAPAKFVKRLND-YSIEKGKPLILEGTFTGTPPISVTWKKNGINVTPS-QRCNITTTEKS 7922
Query: 419 RTLTISQCSLADDAAYQCVV----GGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFE 474
L I ++ D Y C + G + CS ++ + EPP + + LE V VG +
Sbjct: 7923 AILEIPSSTVEDAGQYNCYIENASGKDSCSAQILILEPPYFV-KQLEPVKVSVGDSASLQ 7981
Query: 475 CEVS-EEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALC---TS 530
C+++ V W K +L T+K F+ + L+ N+ + D+G Y +C S
Sbjct: 7982 CQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVAT--LVFNQVDINDSGEY-ICKAENS 8038
Query: 531 GGQALAE--LIVQEKKL--EVYQSIADLMVGAKDQAVFKCEVS-DENVRGVWLKNGKELV 585
G+ A L VQE+KL + + D+ VF C +S E + W K+GK L
Sbjct: 8039 VGEVSASTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGKPLK 8098
Query: 586 PDSRIKVSHIGRVHKLTIDDVTPADEADYSFV---PEGFACNLSAKLHFMEVKIDFVPRQ 642
++ S + L I + YS P G A + SA+L E K
Sbjct: 8099 DSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASS-SARLILTEGK------- 8150
Query: 643 EPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAP 702
PP + + V G + ++G V W K
Sbjct: 8151 NPPFFDIRLA-----PVDAVVGESADFECHVTGTQPIKVSWAK----------------- 8188
Query: 703 EDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQ- 761
DS E + G+ ++ ++ + TV +K D G YT N VG+D
Sbjct: 8189 ----DSRE--------IRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSC 8236
Query: 762 -VNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMR 820
L +K +P + V E G QPI + W +
Sbjct: 8237 TAQLNIKERLIPPSFTKRLSETVEETEGNSFKLEGRVAGSQPI-----------TVAWYK 8285
Query: 821 LNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM-----------PIGP 869
N ++ + E +V ++R +N G+ ++ P P
Sbjct: 8286 NNIEIQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKKP 8345
Query: 870 PSEPTHLAVEDVSD-----TTVSLKWRPPERVG--AGGLDGYSVEYCPEGCSEWVAALQG 922
P HL VS+ + ++ P R+ G + + C + A L+
Sbjct: 8346 PVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFSFASGTAVLE- 8404
Query: 923 LTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQT 982
++D+ + +A N+AG TT VT+++ +P + P +
Sbjct: 8405 --------LRDVAKADSGDYVCKASNVAGSD---TTKSKVTIKD---KPAV-APATKKAA 8449
Query: 983 IQKK---VGEPVNL----------LIPFQGKPRPQVTWTKE--GQPLAGEEVSIRNSPTD 1027
+ + V EP ++ + G P P V WTK Q G V I +
Sbjct: 8450 VDGRLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRVFIHQKGDE 8509
Query: 1028 TILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDK 1065
L IR + SG Y+ E+ E ++ + LQV ++
Sbjct: 8510 AKLEIRDTTKTDSGLYRCVAFNEHGEIESNVNLQVDER 8547
Score = 78.2 bits (191), Expect = 5e-14
Identities = 70/236 (29%), Positives = 112/236 (47%), Gaps = 14/236 (5%)
Query: 396 WLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVV---GGEKCST-ELFVKE 451
W+K+G I+ S K+ F + G R L I L+D Y CV+ EK ST +L V+E
Sbjct: 11151 WMKDGSNIRES-PKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEE 11209
Query: 452 PPVLITRPLEDQLVMV-GQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKKDGQRH 510
PV + LE+++ +V GQ + CE+++E V W KDG ++ E+ + G
Sbjct: 11210 LPVRFVKTLEEEVTVVKGQPLYLSCELNKE-RDVVWRKDG-KIVVEKPGRIVPGVIGLMR 11267
Query: 511 HLIINEAMLEDAGHYALCTSGGQAL----AELIVQEKKLEVYQSIADLMVGAKDQAVFKC 566
L IN+A DAG Y + L +V+ + + + I D V K A+F C
Sbjct: 11268 ALTINDADDTDAGTYTVTVENANNLECSSCVKVVEVIRDWLVKPIRDQHVKPKGTAIFAC 11327
Query: 567 EVSDENVRGVWLKNGKEL--VPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEG 620
+++ + W K E+ P+ + ++ G L I + P D A+Y+ EG
Sbjct: 11328 DIAKDTPNIKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEG 11383
Score = 77.8 bits (190), Expect = 6e-14
Identities = 98/433 (22%), Positives = 154/433 (35%), Gaps = 42/433 (9%)
Query: 847 YAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSV 906
Y + A S A+ + P P + + + L W PP G + Y V
Sbjct: 19366 YTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIV 19425
Query: 907 EYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQE 966
+ W A + TS V+ L G FR+ A N G G PV T EP +
Sbjct: 19426 DKRETSRPNW-AQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFT-EPAIAKN 19483
Query: 967 ILQRPRLQLPRHLRQTIQKKV-----------GEPVNLLIPFQGKPRPQVTWTKEGQ-PL 1014
P P + + + G P+ + + + V WTK + P+
Sbjct: 19484 PYDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYL-LEKRETQAVNWTKVNRKPI 19542
Query: 1015 AGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRV 1074
+ T R +G + + KA P PP +V
Sbjct: 19543 IERTLKATGLQEGTEYEFRVTAINKAGPGK-----PSDASKAAYARDPQYPPGPPAFPKV 19597
Query: 1075 TDAWGLNVALEWKPPQDVGNTELWGYTVQ--KADKKTMEWFTVLEHYRRTHCVVPELIIG 1132
D +V+L W P G + + GY V+ +AD + ++ ++T V L+
Sbjct: 19598 YDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMED 19657
Query: 1133 NGYYFRVFSQNMVGFSDRAATTKE----PVFIPRPGITYEPPNYKALDFSEAPSFTQPLV 1188
Y FRV++ N +G+SD + + + IP G LD + L+
Sbjct: 19658 TQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEG---------ELD----ADLRKTLI 19704
Query: 1189 NRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDG 1248
R AG T L V+G P PKI+W K ++L + + S L +D
Sbjct: 19705 LR---AGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDA 19761
Query: 1249 GIYVCRATNLQGE 1261
G Y+ N G+
Sbjct: 19762 GKYILTLENSCGK 19774
Score = 77.4 bits (189), Expect = 8e-14
Identities = 65/250 (26%), Positives = 112/250 (44%), Gaps = 8/250 (3%)
Query: 375 VSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAY 434
V++ + E+A+ D++ +WL++G+ + ++ + ES G KR L I+ L D Y
Sbjct: 2631 VAESQEAVFECEVANPDSKGEWLRDGKHLPLTNN-IRSESDGHKRRLIIAATKLDDIGEY 2689
Query: 435 QCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQ-VKWLKDGVEL 493
V K S +L V+ V I + L++ V Q F E++ + V+W+K+GV L
Sbjct: 2690 TYKVATSKTSAKLKVEA--VKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVL 2747
Query: 494 TREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIAD 553
E KY G + L I + D Y A A L V+ K + + D
Sbjct: 2748 ESNE--KYAISVKGTIYSLRIKNCAIVDESVYGFRLGRLGASARLHVETVK--IIKKPKD 2803
Query: 554 LMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEAD 613
+ F+ VS + V W E+ P + ++ +VHKL + +++P+D +
Sbjct: 2804 VTALENATVAFEVSVSHDTVPVKWFHKSVEIKPSDKHRLVSERKVHKLMLQNISPSDAGE 2863
Query: 614 YSFVPEGFAC 623
Y+ V C
Sbjct: 2864 YTAVVGQLEC 2873
Score = 77.4 bits (189), Expect = 8e-14
Identities = 52/242 (21%), Positives = 99/242 (40%), Gaps = 3/242 (1%)
Query: 374 QVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAA 433
+V + + + E++ +WLK QEI ++ G K ++ I + D+A
Sbjct: 11850 KVFEKDEAKFECEVSREPKTFRWLKGTQEIT-GDDRFELIKDGTKHSMVIKSAAFEDEAK 11908
Query: 434 YQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVEL 493
Y + S +L ++ + PL+D + F E+S + +VKW K+ L
Sbjct: 11909 YMFEAEDKHTSGKLIIEGIRLKFLTPLKDVTAKEKESAVFTVELSHDNIRVKWFKNDQRL 11968
Query: 494 TREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIAD 553
T + +G+ H + + ++D + G + A+L V E + D
Sbjct: 11969 --HTTRSVSMQDEGKTHSITFKDLSIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQD 12026
Query: 554 LMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEAD 613
KD+ + +CE+S + W K+GKE+ P + G+ L + +D
Sbjct: 12027 YTGVEKDEVILQCEISKADAPVKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQ 12086
Query: 614 YS 615
Y+
Sbjct: 12087 YT 12088
Score = 76.6 bits (187), Expect = 1e-13
Identities = 96/419 (22%), Positives = 148/419 (35%), Gaps = 82/419 (19%)
Query: 393 EVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVV----GGEKCSTELF 448
++ W K +++ +G K F G + TL + + D A Y C G S L
Sbjct: 3269 KISWYKE-EQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLS 3327
Query: 449 VKEPPVL------------ITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTRE 496
V+ P V+ I PL+D + GQ F+C VS +V W ++
Sbjct: 3328 VEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKKIKPS 3387
Query: 497 ETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSG--GQA--------------LAELIV 540
F+ +D + L I EA ED G Y S GQ L E I
Sbjct: 3388 RFFRMTQFED--TYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIE 3445
Query: 541 QEKKLE------VYQSIADLMVGAKDQAVFKCEV-SDENVRGVWLKNGKELVPDSRIKVS 593
QE ++E + + I L V A F CE+ S NVR W K G+E+ + +
Sbjct: 3446 QEIEMEMKAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIR 3505
Query: 594 HIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPG 653
+ L I D +Y+ C S + + + P L P
Sbjct: 3506 SSKYISSLEILRTQVVDCGEYT-------CKASNEYGSVSCTATLTVTEAYPPTFLSRP- 3557
Query: 654 RIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVF 713
++ G + ++G P IWQK + A P+P+ W
Sbjct: 3558 ---KSLTTFVGKAAKFICTVTGTPVIETIWQK-----DGAALSPSPN----------W-- 3597
Query: 714 DKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVP 772
R+ +++ I + +D GVY+ N G D + +ID P
Sbjct: 3598 ------------RISDAENKHILELSNLTIQDRGVYSCKASNKFGADICQAELIIIDKP 3644
Score = 76.6 bits (187), Expect = 1e-13
Identities = 275/1343 (20%), Positives = 445/1343 (33%), Gaps = 243/1343 (18%)
Query: 38 VKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYAV----IAGSSKVKFDLK 93
+KV W + ++I S+K+ ++ + L + + D G Y AGS+ LK
Sbjct: 7335 IKVLWYKDETEIQESSKFRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLK 7394
Query: 94 VIEAEKAEPMLAPAPAPAEAT-GAP--------GEAP----------------------- 121
V K P+ P P E GA G P
Sbjct: 7395 V----KEPPIFRKKPHPIETLKGADVHLECELQGTPPFHVSWYKDKRELRSGKKYKIMSE 7450
Query: 122 ----------APAAELGE---SAPSPKGSS----SAALNGPTPGAPDDPIGLFVMRPQDG 164
AA++GE A + GS S AL P FV + D
Sbjct: 7451 NFLTSIHILNVDAADIGEYQCKATNDVGSDTCVGSIALKAPPR---------FVKKLSDI 7501
Query: 165 EVTVGGSITFSARVAGASLLKPPVVKWFKGKWVDLSSKVGQHLQLHDSYDRASKVYLFEL 224
VG + + GA +P V WFK K G+ ++ D+ + + L
Sbjct: 7502 STVVGKEVQLQTTIEGA---EPISVVWFKDK--------GEIVRESDNIWISYSENIATL 7550
Query: 225 HITDAQPAFTGSYRCEVSTKDKFDCSNFNLTVHEAMGTGDLDLLSAFRRTSLAGGGRRIS 284
+ +PA G Y C++ + + E T LS ++ I
Sbjct: 7551 QFSRVEPANAGKYTCQIKN---------DAGMQECFAT-----LSVLEPATIVEKPESIK 7596
Query: 285 DSHEDTGILDFS-------SLLKKRDSFRTPRDSKLEAPAEEDV--WEILRQAPPSEYER 335
+ DT L+ + S +D D+K + V +I+ AP
Sbjct: 7597 VTTGDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKVSGLKIINVAPSDSG-- 7654
Query: 336 IAFQYGVTDLRGMLKRLKGMR-RDEKKSTAFQKKLEPAYQVSKGHKIRLTVELADHDAEV 394
+ + V + G ++ D +F +KL+ +S + V
Sbjct: 7655 -VYSFEVQNPVGKDSCTASLQVSDRTVPPSFTRKLKETNGLSGSSVVMECKVYGSPPISV 7713
Query: 395 KWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVV----GGEKCSTELFVK 450
W G EI SG KY LT++ +D Y C+ G ++CS L V+
Sbjct: 7714 SWFHEGNEIS-SGRKYQTTLTDNTCALTVNMLEESDSGDYTCIATNMAGSDECSAPLTVR 7772
Query: 451 EPPVLITRPLEDQLVMVGQRVEFECEVSEEGA-QVKWLKDGVELTREETFKYRFKKDGQR 509
EPP + +P + V+ G V F V V W K EL + + +
Sbjct: 7773 EPPSFVQKP-DPMDVLTGTNVTFTSIVKGTPPFSVSWFKGSSELVPGD--RCNVSLEDSV 7829
Query: 510 HHLIINEAMLEDAGHYALCTSGGQALAELIVQ---EKKLEVYQSIADLMVGAKDQAVFKC 566
L + + +G Y S A + + + + D + + +
Sbjct: 7830 AELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKAPAKFVKRLNDYSIEKGKPLILEG 7889
Query: 567 EVSDENVRGV-WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFAC-- 623
+ V W KNG + P R ++ + L I T D Y+ E +
Sbjct: 7890 TFTGTPPISVTWKKNGINVTPSQRCNITTTEKSAILEIPSSTVEDAGQYNCYIENASGKD 7949
Query: 624 NLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIW 683
+ SA++ +E FV + EP K+ + G+ L ++G P V W
Sbjct: 7950 SCSAQILILEPPY-FVKQLEPVKVSV--------------GDSASLQCQLAGTPEIGVSW 7994
Query: 684 QKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEK 743
K D KL T ++ +F +
Sbjct: 7995 YKG---------------------------DTKLRPTTTYKMHFRNNVATLVFNQ--VDI 8025
Query: 744 EDEGVYTVTVKNPVGEDQVN--LTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYD--- 798
D G Y +N VGE + LTV+ +P P S D P +D
Sbjct: 8026 NDSGEYICKAENSVGEVSASTFLTVQEQKLP-----PSFSRQLRDVQETVGLPVVFDCAI 8080
Query: 799 -GGQPI-LGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSR 856
G +PI + + + K K ++ +F L + + + + A N IG +
Sbjct: 8081 SGSEPISVSWYKDGKPLKDSPNVQTSF-LDNTATLNIFKTDRSLAGQYSCTATNPIGSAS 8139
Query: 857 PSPASQPFMPIGPPSEPTHLAVEDV-------------SDTTVSLKWRPPER-VGAGGLD 902
S PP LA D + + W R + +GG
Sbjct: 8140 SSARLILTEGKNPPFFDIRLAPVDAVVGESADFECHVTGTQPIKVSWAKDSREIRSGGK- 8198
Query: 903 GYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPV 962
Y + Y H ++L D + + A N G + T +
Sbjct: 8199 -YQISYLENSA------------HLTVLKVDKGDSGQ--YTCYAVNEVGKDS---CTAQL 8240
Query: 963 TVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTK---EGQPLAGEEV 1019
++E L P + L +T+++ G L G V W K E QP + E+
Sbjct: 8241 NIKERLIPP--SFTKRLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNIEIQPTSNCEI 8298
Query: 1020 SIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPP---QDLR-VT 1075
+ +N+ +L +R A +G Y V + T + + + PP Q L VT
Sbjct: 8299 TFKNNTL--VLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVT 8356
Query: 1076 DAWGLNVALEWKPPQDVGNTELW---GYTVQKADKKTMEWFT---VLEHYRRTHCVVPEL 1129
+ G V L W G ++ +D+ + + + VLE + ++
Sbjct: 8357 VSEGEYVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFSFASGTAVLE--------LRDV 8408
Query: 1130 IIGNGYYFRVFSQNMVGFSDRAATTKEPVFIP-RPGITYEPPNYKALDFSEAPSFTQPLV 1188
+ + + N+ G + TTK V I +P + P KA ++P
Sbjct: 8409 AKADSGDYVCKASNVAG----SDTTKSKVTIKDKPAVA--PATKKAAVDGRLFFVSEPQS 8462
Query: 1189 NRSVIAGYTAMLCCAVRGSPKPKISWFKNGL-DLGEDARFRMFSKQGVLTLEIRKPCPFD 1247
R V+ TA V G P P + W K L + R + K LEIR D
Sbjct: 8463 IR-VVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRVFIHQKGDEAKLEIRDTTKTD 8521
Query: 1248 GGIYVCRATNLQGEARCECRLEV 1270
G+Y C A N GE L+V
Sbjct: 8522 SGLYRCVAFNEHGEIESNVNLQV 8544
Score = 73.6 bits (179), Expect = 1e-12
Identities = 156/762 (20%), Positives = 276/762 (36%), Gaps = 170/762 (22%)
Query: 38 VKVRWQRGGSDISASNKYGLA-TEGTRHTLTVREVGPADQGSYAVIAGSSKVKFDLKVIE 96
++V W + G +I+AS++Y +A EGT +L + V D G++
Sbjct: 4142 MRVSWFKDGKEIAASDRYRIAFVEGTA-SLEIIRVDMNDAGNFT---------------- 4184
Query: 97 AEKAEPMLAPAPAPAEATGAPGEAPAPAAELGESAPSPKGSSSAALNGPTPGAPDDPIGL 156
AT + G + A + + PS
Sbjct: 4185 --------------CRATNSVGSKDSSGALIVQEPPS----------------------- 4207
Query: 157 FVMRPQDGEVTVGGSITFSARVAGASLLKPPVVKWFKGKWVDLSSKVGQHLQLHDSYDRA 216
FV +P +V G ++ + G++ P ++WFKG +S G ++ + +
Sbjct: 4208 FVTKPGSKDVLPGSAVCLKSTFQGST---PLTIRWFKGNKELVSG--GSCYITKEALESS 4262
Query: 217 SKVYLFELHITDAQPAFTGSYRCEVST-KDKFDCSNFNLTVHEAMGTGDLDLLSAFRRTS 275
++YL + + +G+Y C+VS +CS NL V E +
Sbjct: 4263 LELYL-------VKTSDSGTYTCKVSNVAGGVECSA-NLFVKEPATFVEK---------- 4304
Query: 276 LAGGGRRISDSHEDTGILDFSSLLKKRDSFRTPRDSKLEAPAEEDVWEILRQAPPSEYER 335
L+ S LLKK D+ + P + + R+ S R
Sbjct: 4305 -----------------LEPSQLLKKGDATQLACKVTGTPPIKITWFANDREIKESSKHR 4347
Query: 336 IAF----------QYGVTDLRGMLKRLKGMRRDE--------KKSTAFQKKLEPAYQVSK 377
++F G+ D + + + K+S F K+ +P +V K
Sbjct: 4348 MSFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVIVKESPYFTKEFKPI-EVLK 4406
Query: 378 GHKIRLTVELADHDA-EVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQC 436
+ + L E+A E+ W K+ I SG KY +L I + AD YQC
Sbjct: 4407 EYDVMLLAEVAGTPPFEITWFKDNT-ILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQC 4465
Query: 437 ----VVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEE-GAQVKWLKDGV 491
VG CS + ++EPP I + +E + G F+ + V WLKD
Sbjct: 4466 RVTNEVGSSICSARVTLREPPSFIKK-IESTSSLRGGTAAFQATLKGSLPITVTWLKDSD 4524
Query: 492 ELTREETFKYRFKKDGQRHHLIINEAMLEDAGHY---ALCTSGGQALAELIVQEKKLEVY 548
E+T ++ + F+ + L ++ ++ G Y A +G Q + L+ ++ +
Sbjct: 4525 EITEDDNIRMTFENNVAS--LYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKEPATIT 4582
Query: 549 QSIADLMVGAKDQAVFKCEVSD-ENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVT 607
+ + V D A + + S + + W K+G+EL S+ K+S V L I
Sbjct: 4583 EEAVSIDVTQGDPATLQVKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTE 4642
Query: 608 PADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKL 667
D +Y+F + S K + + P +D + G+ +
Sbjct: 4643 KKDSGEYTFEVQNDVGRSSCKARINVLDLIIPPSFTKKLKKMDS----------IKGSFI 4692
Query: 668 RLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRV 727
L+ ++G ++ W K ++ S+++ F
Sbjct: 4693 DLECIVAGSHPISIQWFK---------------DDQEISASEKYKFSFH----------- 4726
Query: 728 ETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQV--NLTVK 767
+ T I +EG D G YT + N G +Q +LTVK
Sbjct: 4727 DNTAFLEISQLEGT---DSGTYTCSATNKAGHNQCSGHLTVK 4765
Score = 71.6 bits (174), Expect = 4e-12
Identities = 60/195 (30%), Positives = 92/195 (47%), Gaps = 17/195 (8%)
Query: 439 GGEKCSTEL----FVKEPPVLITRPLEDQLV----MVGQRVEFECEVSEEGAQVKWLKDG 490
GGEK E +K P+ + ++D ++ VG FEC VS A W+KDG
Sbjct: 11096 GGEKPPDEAPFTYQLKAVPLKFVKEIKDIILTESEFVGSSAIFECLVSPSTAITTWMKDG 11155
Query: 491 VELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQ----ALAELIVQEKKLE 546
+ E+ K+RF DG+ L I + L DAG Y G + A+L+V+E +
Sbjct: 11156 SNI--RESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEELPVR 11213
Query: 547 VYQSIADLMVGAKDQAVF-KCEVSDENVRGVWLKNGKELV-PDSRIKVSHIGRVHKLTID 604
+++ + + K Q ++ CE++ E VW K+GK +V RI IG + LTI+
Sbjct: 11214 FVKTLEEEVTVVKGQPLYLSCELNKER-DVVWRKDGKIVVEKPGRIVPGVIGLMRALTIN 11272
Query: 605 DVTPADEADYSFVPE 619
D D Y+ E
Sbjct: 11273 DADDTDAGTYTVTVE 11287
Score = 70.9 bits (172), Expect = 8e-12
Identities = 62/255 (24%), Positives = 106/255 (41%), Gaps = 6/255 (2%)
Query: 386 ELADHDAEVKWLKNGQEIQMS-GSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCS 444
++A +KW K EI K G L I D A Y + G++
Sbjct: 11328 DIAKDTPNIKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEGKRYP 11387
Query: 445 TELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFK 504
+L + E V + +P+ED + + F+ E+SE +W G L T + K
Sbjct: 11388 AKLTLGEREVELLKPIEDVTIYEKESASFDAEISEADIPGQWKLKGELLRPSPTCE--IK 11445
Query: 505 KDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVF 564
+G + L +++ L+ AG A L V+E +L+ + D+ V + QA F
Sbjct: 11446 AEGGKRFLTLHKVKLDQAGEVLYQALNAITTAILTVKEIELDFAVPLKDVTVPERRQARF 11505
Query: 565 KCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACN 624
+C ++ E +W K + + + G+ H L I+D DE Y+ EG
Sbjct: 11506 ECVLTRE-ANVIWSKGPDIIKSSDKFDIIADGKKHILVINDSQFDDEGVYTAEVEG--KK 11562
Query: 625 LSAKLHFMEVKIDFV 639
SA+L +++ F+
Sbjct: 11563 TSARLFVTGIRLKFM 11577
Score = 70.1 bits (170), Expect = 1e-11
Identities = 144/622 (23%), Positives = 227/622 (36%), Gaps = 79/622 (12%)
Query: 675 GDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRS 734
G P VI + +T K PA + TG ++ +KK L + T +
Sbjct: 24607 GRPEAIVITRNNVTLKWKKPAYDG--GSKITG----YIVEKKDLPDGRWMKASFTNVLET 24660
Query: 735 IFTVEGAEKEDEGVYTVTVKNPVG------EDQVNLTVK-VIDVPDAPAAPKISNVGEDS 787
FTV G ++ + V +N G + +T + ID P+A PK +V
Sbjct: 24661 EFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVH 24720
Query: 788 CTVQWEPPAYDGGQPILGYILERKKKKSYRWM-RLNF-DLIQELSHEARRMI--EGVVYE 843
+ A G+PI + + K+ R+ IQ+ + + I +G Y
Sbjct: 24721 AGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYI 24780
Query: 844 MRVYAVNAIGMSRPSPASQPFMPI-GPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLD 902
+++ + +G ++ P + + GPP P L V V+ L W PP + G +
Sbjct: 24781 LKL---SNVGGTKSIPITVKVLDRPGPPEGP--LKVTGVTAEKCYLAWNPPLQDGGANIS 24835
Query: 903 GYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPV 962
Y +E W + + K LP G +FRV A N G G P+ + PV
Sbjct: 24836 HYIIEKRETSRLSWTQVSTEVQALNYKVTKLLP-GNEYIFRVMAVNKYGIGEPLESG-PV 24893
Query: 963 TVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKE----GQPLAGEE 1018
T + P G P + K VTW + G + G
Sbjct: 24894 TACNPYKPP----------------GPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYI 24937
Query: 1019 VSIR----------NSPTDTILFIRAARRVHSGTYQVTVRIENME-----DKATLVLQVV 1063
+ R N T T L +R +Y+ V EN + ++ +
Sbjct: 24938 LEKRDKEGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRAC 24997
Query: 1064 DK---PSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEH-- 1118
D P PP + +VTD +V+L W P G + GY V+ + EW T
Sbjct: 24998 DALYPPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTG 25057
Query: 1119 YRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFS 1178
+ V +L Y FR+ + N G + A V R EPP + LD
Sbjct: 25058 LQGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQER----IEPPEIE-LD-- 25110
Query: 1179 EAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTL 1238
+ +V R A T L ++G P+P++ W K L + A+ + S +L +
Sbjct: 25111 --ADLRKVVVLR---ASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVI 25165
Query: 1239 EIRKPCPFDGGIYVCRATNLQG 1260
+ FD G Y N G
Sbjct: 25166 D--NVTRFDSGRYNLTLENNSG 25185
Score = 68.9 bits (167), Expect = 3e-11
Identities = 66/244 (27%), Positives = 95/244 (38%), Gaps = 30/244 (12%)
Query: 1034 AARRVHSGTYQVTVRIENME----------------DKATLVLQVVDKPSPPQDLRVTDA 1077
A + H TY+VT E E + T ++ + PSPP L + D
Sbjct: 20917 ATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDI 20976
Query: 1078 WGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYF 1137
V+L W P+ G +++ GY ++ K + +W T + + CVV L G Y F
Sbjct: 20977 TKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQW-THITTVKGLECVVRNLTEGEEYTF 21035
Query: 1138 RVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYT 1197
+V + N G R+A + RP I E LD Q LV AG
Sbjct: 21036 QVMAVNSAG---RSAPRES-----RPVIVKEQTMLPELDLR---GIYQKLVIAK--AGDN 21082
Query: 1198 AMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATN 1257
+ V G PKP ++W K L + R + L I + D G Y A N
Sbjct: 21083 IKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARN 21142
Query: 1258 LQGE 1261
+ GE
Sbjct: 21143 IVGE 21146
Score = 67.0 bits (162), Expect = 1e-10
Identities = 96/461 (20%), Positives = 178/461 (38%), Gaps = 66/461 (14%)
Query: 351 RLKGMRRDEKKSTAFQKKLEPAYQVSKGHKIRLTVELADHDA--------EVKWLKNGQE 402
++ + D+ S K P++ V G + + + A ++KW K+ E
Sbjct: 5310 KVSNVAGDDACSGILTVKEPPSFLVKPGRQQAIPDSTVEFKAILKGTPPFKIKWFKDDVE 5369
Query: 403 IQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVV----GGEKCSTELFVKEPPVLITR 458
+ +SG K G+ L + + Y C V G + C+T L V EPP + +
Sbjct: 5370 L-VSGPKCFIGLEGSTSFLNLYSVDASKTGQYTCHVTNDVGSDSCTTMLLVTEPPKFVKK 5428
Query: 459 PLEDQLVMVGQRVEFECEVS-EEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEA 517
++V G EC+++ +V W ++ EL + KYR + +N
Sbjct: 5429 LEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASD--KYRMTFIDSVAVIQMNNL 5486
Query: 518 MLEDAGHYALCTS---GGQALAELIVQEKKLEVYQSIADLMVGAKDQAV-FKCEVS-DEN 572
ED+G + +C + G V K+ V+ S ++ K+ V +CE+S
Sbjct: 5487 STEDSGDF-ICEAQNPAGSTSCSTKVIVKEPPVFSSFPPIVETLKNAEVSLECELSGTPP 5545
Query: 573 VRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFM 632
VW K+ ++L + K++ + I +V +D +Y C ++
Sbjct: 5546 FEVVWYKDKRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYH-------CKAQNEVG-S 5597
Query: 633 EVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNK 692
+ + V +EPP+ +++ VVAG L I G
Sbjct: 5598 DTCVCTVKLKEPPRFVSKL-----NSLTVVAGEPAELQASIEG----------------- 5635
Query: 693 APARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVT 752
A+P +W+ +K+ + +R+ ++ + AE + G Y
Sbjct: 5636 --AQPI---------FVQWLKEKEEVIRESENIRITFVENVATLQFAKAEPANAGKYICQ 5684
Query: 753 VKNPVGEDQVNLTVKVID--VPDAPAAPKISNVGEDSCTVQ 791
+KN G + T+ V++ V A P VGE +CT++
Sbjct: 5685 IKNDGGMRENMATLMVLEPAVIVEKAGPMTVTVGE-TCTLE 5724
Score = 66.6 bits (161), Expect = 1e-10
Identities = 166/772 (21%), Positives = 275/772 (35%), Gaps = 163/772 (21%)
Query: 577 WLKNGKELVPD--SRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEV 634
W +G+++V D ++ + G L I TP+D +++ V + A S + +
Sbjct: 1490 WFHDGQQIVNDYTHKVVIKEDG-TQSLIIVPATPSDSGEWTVVAQNRAGRSSISVI---L 1545
Query: 635 KIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAP 694
++ V Q P + + G++L + V +G+P P ++W K
Sbjct: 1546 TVEAVEHQVKPMFVEKLKN-----VNIKEGSRLEMKVRATGNPNPDIVWLK--------- 1591
Query: 695 ARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVK 754
+SD V K ++R+E TK + ++ +D YT T
Sbjct: 1592 ------------NSDIIVPHKY------PKIRIEGTKGEAALKIDSTVSQDSAWYTATAI 1633
Query: 755 NPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKK 814
N G D V V V++ P +P I+ R
Sbjct: 1634 NKAGRDTTRCKVNV--------------------EVEFAEP-----EPERKLIIPRG--- 1665
Query: 815 SYRWMRLNFDLIQ--ELSHEARRMIEGVVYEMRVYA-------VNAIGMSRPSPASQP-- 863
+YR + ++ L + + EG +Y+ + ++ + R PA
Sbjct: 1666 TYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGPAHFECR 1725
Query: 864 FMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPE-GCSEWVAALQG 922
PIG P+ + D + + R G LD Y V Y + G A +
Sbjct: 1726 LTPIGDPTMVVEW-LHDGKPLEAANRLRMINEFGYCSLD-YGVAYSRDSGIITCRATNKY 1783
Query: 923 LTEHTS--ILVKD---------LPTGARLLFRVRA-HNMAGPGAPVTTTEPVTVQEILQR 970
T+HTS ++VKD LP G + L R+ MA GA T T Q+ Q+
Sbjct: 1784 GTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVT---TDQKEKQK 1840
Query: 971 PRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLA-GEEVSIRNSPTDTI 1029
P + L + ++ GE G P+P+V W GQ + + +R D I
Sbjct: 1841 PDIVL---YPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRY---DGI 1894
Query: 1030 LFIRAARRVHSGTYQVTVRIEN----MEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALE 1085
++ T +V V EN +E K L +Q +D R L A E
Sbjct: 1895 HYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQ------QREDFRSV----LRRAPE 1944
Query: 1086 WKPPQDVGNTELWGYTVQKADK-----KTMEWFTVLEHYRRTHCVVPELI---------- 1130
+P V + VQK D+ +T E + R TH VPE
Sbjct: 1945 PRPEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKVPEESEELRSKFKRR 2004
Query: 1131 IGNGYYFRV---------------------------FSQNMVGFSDRAATTKEPVFIPRP 1163
GYY + +++ + +A + + IP
Sbjct: 2005 TEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIP-- 2062
Query: 1164 GITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGE 1223
T++P + EAP + + +++V G A V G P P+ W+KNG+ +
Sbjct: 2063 --TFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIER 2120
Query: 1224 DAR-FRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVRVPQ 1274
R + + + V L IR D + +A N+ GE L V+ Q
Sbjct: 2121 SDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQ 2172
Score = 65.5 bits (158), Expect = 3e-10
Identities = 64/246 (26%), Positives = 101/246 (41%), Gaps = 35/246 (14%)
Query: 15 KPRSVEVAAGSPAVFEAETERAGVK-VRWQRGGSDISASNKYGLATEGTRHTLTVREVGP 73
KPRS+ V G A F +T+ V V W R G +S S ++ + T + T + V
Sbjct: 32566 KPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQA 32625
Query: 74 ADQGSYAVIA----GSSKVKFDLKVIEAEKAEPMLAPAPAPAEATGAPGEAPAPAAELGE 129
+D+G+Y+V+ G + +F L + +A E + P ++P P + E
Sbjct: 32626 SDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRV--------KSPEPRVKSPE 32677
Query: 130 SAPSPKGSSSAALNGPTPGAPDDPIGLFVMRPQDGEVTVGGSITFSAR------------ 177
+ SPK S + P +P + + Q V+ IT +
Sbjct: 32678 AVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPVSAPPKITQFLKAEASKEIAKLTC 32737
Query: 178 VAGASLLKPPVVKWFK-GKWVDLSSKVGQHLQLHDSYDRASKVYLFELHITDAQPAFTGS 236
V +S+L+ V W+K GK K H Q H S D +EL I + + G
Sbjct: 32738 VVESSVLRAKEVTWYKDGK----KLKENGHFQFHYSADGT-----YELKINNLTESDQGE 32788
Query: 237 YRCEVS 242
Y CE+S
Sbjct: 32789 YVCEIS 32794
Score = 65.1 bits (157), Expect = 4e-10
Identities = 70/293 (23%), Positives = 120/293 (40%), Gaps = 38/293 (12%)
Query: 981 QTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPL-AGEEVSIRNSPTDTILFIRAARRVH 1039
+ +Q + + V+L + VTW+K+GQ L G++ I L I A+
Sbjct: 3651 EPVQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKIATLEIPLAKLKD 3710
Query: 1040 SGTYQVTVRIENMEDKATLVLQVVDKPS------PPQDLRVTDAWGLNVALEWKPPQDVG 1093
SGTY T E + + V + PS P + ++ L+ L+ P V
Sbjct: 3711 SGTYVCTASNEAGSSSCSATVTVREPPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQV- 3769
Query: 1094 NTELWGYTVQKADKKTMEWFTVLEHYRRTHCV--VPELIIGNGYYFRVFSQNMVGFSDRA 1151
T K +K+ E TV ++ + + + ++ + + + + N VG SD
Sbjct: 3770 -------TWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVG-SDSC 3821
Query: 1152 ATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPK 1211
+T + E PSF + L ++ G A+L C V G+ +
Sbjct: 3822 ST--------------------EIVIKEPPSFIKTLEPADIVRGTNALLQCEVSGTGPFE 3861
Query: 1212 ISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARC 1264
ISWFK+ + ++R+FS++ ++ LEI D G Y C N G+ C
Sbjct: 3862 ISWFKDKKQIRSSKKYRLFSQKSLVCLEIFSFNSADVGEYECVVANEVGKCGC 3914
Score = 63.5 bits (153), Expect = 1e-09
Identities = 102/453 (22%), Positives = 153/453 (33%), Gaps = 71/453 (15%)
Query: 820 RLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPAS-------QPFMPIGPPSE 872
R+N ++ L + + + VY V A S + A P +GP
Sbjct: 28002 RMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGP--- 28058
Query: 873 PTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVK 932
+ +++ ++L W P G + Y +E W A ++ E S
Sbjct: 28059 ---IRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAW-ALIEDKCEAQSYTAI 28114
Query: 933 DLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQ---EILQRPRLQLPRHLRQTI------ 983
L G FRV A N G G P+ + +PV Q + P + P ++
Sbjct: 28115 KLINGNEYQFRVSAVNKFGVGRPLDS-DPVVAQIQYTVPDAPGIPEPSNITGNSITLTWA 28173
Query: 984 --QKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSG 1041
+ G + I + + + W K I P F +
Sbjct: 28174 RPESDGGSEIQQYI-LERREKKSTRWVKV----------ISKRPISETRF-KVTGLTEGN 28221
Query: 1042 TYQVTVRIENME--------DKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVG 1093
Y+ V EN + + V+ P PP ++VTD V+LEW P G
Sbjct: 28222 EYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDG 28281
Query: 1094 NTELWGYTVQKADKKTMEWFTV-LEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAA 1152
E+ GY ++ +W V E +T V +L G Y FRV + N G D
Sbjct: 28282 GMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCE 28341
Query: 1153 TTKEPVFIPRPGITYEPPNYKALDFSEAP------SFTQPLVNRSVIAGYTAMLCCAVRG 1206
T KA+D AP +F Q V R AG + L A +G
Sbjct: 28342 VTG---------------TIKAVDRLTAPELDIDANFKQTHVVR---AGASIRLFIAYQG 28383
Query: 1207 SPKPKISWFKNGLDLGEDARFRMFSKQGVLTLE 1239
P P W K +L A LT+E
Sbjct: 28384 RPTPTAVWSKPDSNLSLRADIHTTDSFSTLTVE 28416
Score = 63.5 bits (153), Expect = 1e-09
Identities = 98/435 (22%), Positives = 159/435 (36%), Gaps = 53/435 (12%)
Query: 844 MRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDG 903
++ ++V + + RP P + P + V VS + L W P+ G +
Sbjct: 28728 VKTFSVTVVVIGRPGPVTGP------------IEVSSVSAESCVLSWGEPKDGGGTEITN 28775
Query: 904 YSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAG-----PGAPVTT 958
Y VE G + W + + T I V L FRV + N G AP+
Sbjct: 28776 YIVEKRESGTTAW-QLVNSSVKRTQIKVTHLTKYMEYSFRVSSENRFGVSKPLESAPIIA 28834
Query: 959 TEPVTVQEILQRPRLQLPRHLRQTI--QKKVGEPVNLLIPF--QGKPRPQVTWTKEGQPL 1014
P RP + +I ++ + + +I + + K R + W KE +
Sbjct: 28835 EHPFVPPSAPTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVP 28894
Query: 1015 AGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRV 1074
E T + + R ++ V + + + VD P P+ V
Sbjct: 28895 CLE---CNYKVTGLVEGLEYQFRTYA-LNAAGVSKASEASRPIMAQNPVDAPGRPE---V 28947
Query: 1075 TDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTM---EW----FTVLEHYRRTHCVVP 1127
TD V+L W P G +++ GY +++ + W +T++ T +
Sbjct: 28948 TDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALS 29007
Query: 1128 ELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPL 1187
E G+ Y FRV ++N G + + + PV Y PP + LD
Sbjct: 29008 E---GDTYEFRVLAKNAAGVISKGSESTGPVTCRDE---YAPPKAE-LDARLHGDLV--- 29057
Query: 1188 VNRSVIAGYTAMLCCAVRGSPKPKISWFKNG--LDLGEDARFRMFSKQGVLTLEIRKPCP 1245
++ AG +L AV G P+PKI W K LDL E + K+ T I+
Sbjct: 29058 ---TIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRA--TAVIKFCDR 29112
Query: 1246 FDGGIYVCRATNLQG 1260
D G Y N G
Sbjct: 29113 SDSGKYTLTVKNASG 29127
Score = 63.2 bits (152), Expect = 2e-09
Identities = 81/335 (24%), Positives = 134/335 (40%), Gaps = 41/335 (12%)
Query: 950 AGPG---APVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVT 1006
AGPG AP T+PV VQ++++ G V G P+P V
Sbjct: 1074 AGPGEPAAPYFITKPV-VQKLVE------------------GGSVVFGCQVGGNPKPHVY 1114
Query: 1007 WTKEGQPLAGE---EVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVV 1063
W K G PL +VS + L I +G Y + VR ++ E A+ L
Sbjct: 1115 WKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEE 1174
Query: 1064 DKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKK-TMEWFTVLEHYRRT 1122
+ + V + P+ VG T G+ + +K+ E + + +
Sbjct: 1175 ADYELLMKSQQEMLYQTQVTAFVQEPK-VGETAP-GFVYSEYEKEYEKEQALIRKKMAKD 1232
Query: 1123 HCVVPELIIGNGYYFRVFSQNMVGFSDRAA--TTKEPVFIPRPGITYEPPNYKALDFSEA 1180
VV + ++ F + ++ + TT E + + + A+D SE+
Sbjct: 1233 TVVVRTYVEDQEFHISSFEERLIKEIEYRIIKTTLEEL------LEEDGEEKMAVDISES 1286
Query: 1181 PS----FTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRM-FSKQGV 1235
+ F + N ++ G C + G P PKI+W+K+G + R++M F + G
Sbjct: 1287 EAVESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGR 1346
Query: 1236 LTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
+L I P D GIY A+N++G A C +L V
Sbjct: 1347 ASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYV 1381
Score = 62.4 bits (150), Expect = 3e-09
Identities = 65/275 (23%), Positives = 104/275 (37%), Gaps = 65/275 (23%)
Query: 1032 IRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQD 1091
++A +V G Y + ++N + P PP D+ V + + + WKPP
Sbjct: 14553 VKAVNKVGGGEY---IELKN----PVIAQDPKQPPDPPVDVEVHNPTAEAMTITWKPPLY 14605
Query: 1092 VGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELII-------GNGYYFRVFSQNM 1144
G +++ GY ++K K W EH +VP L G Y FRV ++N
Sbjct: 14606 DGGSKIMGYIIEKIAKGEERWKRCNEH------LVPILTYTAKGLEEGKEYQFRVRAENA 14659
Query: 1145 VGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAV 1204
G S+ + T P KA+D +AP + V G L ++
Sbjct: 14660 AGISEPSRAT---------------PPTKAVDPIDAPKVILR-TSLEVKRGDEIALDASI 14703
Query: 1205 RGSPKPKISWFKN-GLDLGEDARFRMF----------------------------SKQGV 1235
GSP P I+W K+ + + E+ + R SK+G
Sbjct: 14704 SGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGE 14763
Query: 1236 LTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
L +R D G+Y+ + N G A+ C + V
Sbjct: 14764 SQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSV 14798
Score = 60.5 bits (145), Expect = 1e-08
Identities = 55/197 (27%), Positives = 95/197 (48%), Gaps = 10/197 (5%)
Query: 451 EPPVLITRPLEDQLVMVGQRVEFECEV-SEEGAQVKWLKDGVELTREETFKYRFKKDGQR 509
E P + R ++ Q V G F V + + +W K+GV++ R + + + +D
Sbjct: 2076 EAPKIFER-IQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNV- 2133
Query: 510 HHLIINEAMLEDAGHY---ALCTSG-GQALAELIVQEKKLEVY-QSIADLMVGAKD-QAV 563
L+I + ED+ A+ +G + A L+VQ K+L + Q + D++ KD A
Sbjct: 2134 CELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMAT 2193
Query: 564 FKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFV-PEGFA 622
F+CE S+ V+ W K+G E+ + ++ +VH L+I + +D DYS V E
Sbjct: 2194 FECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDEN 2253
Query: 623 CNLSAKLHFMEVKIDFV 639
+AKL ++FV
Sbjct: 2254 VKTTAKLIVEGAVVEFV 2270
Score = 59.7 bits (143), Expect = 2e-08
Identities = 28/95 (29%), Positives = 46/95 (48%)
Query: 1176 DFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGV 1235
+ S+AP+F ++++ G + C + G P P+I WFKN L + + + + V
Sbjct: 33129 ELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNV 33188
Query: 1236 LTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
+LEIR D G Y +A N +G+ L V
Sbjct: 33189 YSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 33223
Score = 59.3 bits (142), Expect = 2e-08
Identities = 84/343 (24%), Positives = 125/343 (36%), Gaps = 68/343 (19%)
Query: 441 EKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEV-SEEGAQVKWLKDGVELTREETF 499
E S + F + IT + V GQ F V S+ A+VKW +GVEL +E+
Sbjct: 32361 EVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVEL--QESS 32418
Query: 500 KYRFKKDGQRHHLIINEAMLEDAGHY-ALCTS-GGQALAELIVQEKKLEVYQSIADLMVG 557
K + L I + +D+G Y A+CT+ G+A A L V
Sbjct: 32419 KIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEA--------------SDYATLDVT 32464
Query: 558 AKDQAVFKCEVSDENV-RGVWLKNGKELVPDSRIKVSHIGRVHKLTIDD--------VTP 608
D + + DE V R V+ EL VS + ++ +T
Sbjct: 32465 GGDYTTYASQRRDEEVPRSVF----PELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTE 32520
Query: 609 ADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRI---PDTIVVVAGN 665
E+ S+ A SA L ++ R KI RI P ++ V G
Sbjct: 32521 TRESLSSYEHSASAEMKSAALEEKSLEEKSTTR----KIKTTLAARILTKPRSMTVYEGE 32576
Query: 666 KLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRV 725
R G+P PTV W + K + T R
Sbjct: 32577 SARFSCDTDGEPVPTVTWLR-----------------------------KGQVLSTSARH 32607
Query: 726 RVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKV 768
+V TTK +S F + + DEG Y+V V+N G+ + T+ +
Sbjct: 32608 QVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTI 32650
Score = 57.0 bits (136), Expect = 1e-07
Identities = 69/305 (22%), Positives = 116/305 (38%), Gaps = 26/305 (8%)
Query: 976 PRHLRQTIQKKVGEPVNLLIPFQ--GKPRPQVTWTKEGQPLA-GEEVSIRNSPTDTILFI 1032
P + Q + + E N+L + G+P P++ W K P++ VSI S L I
Sbjct: 33134 PAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEI 33193
Query: 1033 RAARRVHSGTYQVTVRIENMEDKAT---LVLQVVDKPSPPQDLRVTDAWGLNVALEWKPP 1089
R A SG Y + + + AT +VL +V++PS LR + L + +
Sbjct: 33194 RNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQGSFSSQSV 33253
Query: 1090 Q-DVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFS 1148
Q E + + +M ++ + E + + S + +G S
Sbjct: 33254 QMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFV------EMSSSSFMGIS 33307
Query: 1149 DRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSP 1208
+ + + GI PP +AL PS + S+ G + CA G P
Sbjct: 33308 NMTQLESSTSKMLKAGIRGIPPKIEAL-----PS------DISIDEGKVLTVACAFTGEP 33356
Query: 1209 KPKISWFKNG--LDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCEC 1266
P+++W G + E RF + + + TL I DGG+Y N G
Sbjct: 33357 TPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATV 33416
Query: 1267 RLEVR 1271
+ +R
Sbjct: 33417 NIHIR 33421
Score = 56.6 bits (135), Expect = 1e-07
Identities = 81/342 (23%), Positives = 131/342 (38%), Gaps = 44/342 (12%)
Query: 945 RAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQ 1004
+A N G V+ + +TVQE Q+ R LR +Q+ VG PV G
Sbjct: 8034 KAENSVGE---VSASTFLTVQE--QKLPPSFSRQLRD-VQETVGLPVVFDCAISGSEPIS 8087
Query: 1005 VTWTKEGQPLAGEEVSIRNSPTDTI--LFIRAARRVHSGTYQVTVR--IENMEDKATLVL 1060
V+W K+G+PL + +++ S D L I R +G Y T I + A L+L
Sbjct: 8088 VSWYKDGKPLK-DSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARLIL 8146
Query: 1061 QVVDKPS------PPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFT 1114
P P D V ++ + P V W ++ +
Sbjct: 8147 TEGKNPPFFDIRLAPVDAVVGESADFECHVTGTQPIKVS----WAKDSREIRSGGKYQIS 8202
Query: 1115 VLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTK-EPVFIPRPGITYEPPNYK 1173
LE+ H V ++ G+ + ++ N VG A + IP
Sbjct: 8203 YLEN--SAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKERLIP------------ 8248
Query: 1174 ALDFSEAPSFTQPLVNR-SVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSK 1232
PSFT+ L G + L V GS ++W+KN +++ + + K
Sbjct: 8249 -------PSFTKRLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNIEIQPTSNCEITFK 8301
Query: 1233 QGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVRVPQ 1274
L L++RK D G+Y C+ +N G A C + ++ P+
Sbjct: 8302 NNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPK 8343
Score = 55.8 bits (133), Expect = 3e-07
Identities = 155/744 (20%), Positives = 254/744 (34%), Gaps = 112/744 (15%)
Query: 7 KPVSAFSKKPRSVEVAAGSPAVFEAETERAG-VKVRWQRGGSDISASNKYGLATEGTRHT 65
K FS P VE + E E +V W + + +S KY +A++ +
Sbjct: 5514 KEPPVFSSFPPIVETLKNAEVSLECELSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHTS 5573
Query: 66 LTVREVGPADQGSYAVIAGSSKVKFDLKVIEAEKAEP-----------MLAPAPAPAEAT 114
+ + V +D G Y A ++V D V + EP ++A PA +A+
Sbjct: 5574 IHILNVDTSDIGEYHCKA-QNEVGSDTCVCTVKLKEPPRFVSKLNSLTVVAGEPAELQAS 5632
Query: 115 GAPGEAP--------------------------APAAELGESAPSPKGSSSAALNGPTPG 148
G P + ++ P+ G + G
Sbjct: 5633 -IEGAQPIFVQWLKEKEEVIRESENIRITFVENVATLQFAKAEPANAGKYICQIKNDG-G 5690
Query: 149 APDDPIGLFVMRPQ-------DGEVTVGGSITFSARVAGASLLKPPVVKWFK-GKWVDLS 200
++ L V+ P VTVG + T +VAG L V+W+K GK + S
Sbjct: 5691 MRENMATLMVLEPAVIVEKAGPMTVTVGETCTLECKVAGTPELS---VEWYKDGKLLTSS 5747
Query: 201 SKVGQHLQLHDSYDRASKVYLFELHITDAQPAFTGSYRCEVSTK-DKFDCSNFNLTVHEA 259
K Y++ S + + + DA G+Y +V K C+
Sbjct: 5748 QK-----HKFSFYNKISSLRILSVERQDA-----GTYTFQVQNNVGKSSCT-------AV 5790
Query: 260 MGTGDLDLLSAFRRTSLAGGGRRISDSHEDTGILDFS--SLLKKRDSFRTPRDSKLEAPA 317
+ D + +F R GG + + + S S+ + + +K +
Sbjct: 5791 VDVSDRAVPPSFTRRLKNTGGVLGASCILECKVAGSSPISVAWFHEKTKIVSGAKYQTTF 5850
Query: 318 EEDVWEI----LRQAPPSEYERIAFQY-GVTDLRGMLKRLKGMRRDEKKSTAFQKKLEPA 372
++V + L + Y +A G + R +L ++ +F K+ EP
Sbjct: 5851 SDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLT--------VQEPPSFVKEPEPL 5902
Query: 373 YQVSKGHKIRLT-VELADHDAEVKWLKNGQEIQMSGSKYI-FESIGAKRTLTISQCSLAD 430
+V G + T V +V W + +E+ I FE A+ L + ++
Sbjct: 5903 -EVLPGKNVTFTSVIRGTPPFKVNWFRGARELVKGDRCNIYFEDTVAE--LELFNIDISQ 5959
Query: 431 DAAYQCVV----GGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEE-GAQVK 485
Y CVV G C+T LFVKEP + R L D V G+ + E + V
Sbjct: 5960 SGEYTCVVSNNAGQASCTTRLFVKEPAAFLKR-LSDHSVEPGKSIILESTYTGTLPISVT 6018
Query: 486 WLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYAL---CTSGGQALAELIVQE 542
W KDG +T E K + L I + DAG Y+ +G L+
Sbjct: 6019 WKKDGFNITTSE--KCNIVTTEKTCILEILNSTKRDAGQYSCEIENEAGRDVCGALVSTL 6076
Query: 543 KKLEVYQSIADLMVGAKDQAVFKCEVS-DENVRGVWLKNGKELVPDSRIKVSHIGRVHKL 601
+ + L D +C+V+ + W K +L P + V L
Sbjct: 6077 EPPYFVTELEPLEAAVGDSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYRTYFTNNVATL 6136
Query: 602 TIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVV 661
+ V D +Y+ E S+K F RQ PP R I
Sbjct: 6137 VFNKVNINDSGEYTCKAENSIGTASSKTVFR-----IQERQLPPSF-----ARQLKDIEQ 6186
Query: 662 VAGNKLRLDVPISGDPAPTVIWQK 685
G + L ++G V W +
Sbjct: 6187 TVGLPVTLTCRLNGSAPIQVCWYR 6210
Score = 54.7 bits (130), Expect = 6e-07
Identities = 27/94 (28%), Positives = 44/94 (46%)
Query: 1181 PSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEI 1240
P+ L N +VI G + L C + G P P ++W++ + F++ + G+ L I
Sbjct: 943 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMI 1002
Query: 1241 RKPCPFDGGIYVCRATNLQGEARCECRLEVRVPQ 1274
R+ D G + C A N G C L V+V +
Sbjct: 1003 REAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSE 1036
Score = 54.7 bits (130), Expect = 6e-07
Identities = 24/85 (28%), Positives = 44/85 (51%)
Query: 12 FSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREV 71
F KP+++E+ G A F + V+W+R + + +KY + +G + L V++
Sbjct: 12554 FISKPQNLEILEGEKAEFVCSISKESFPVQWKRDDKTLESGDKYDVIADGKKRVLVVKDA 12613
Query: 72 GPADQGSYAVIAGSSKVKFDLKVIE 96
D G+Y V+ G+++ L VIE
Sbjct: 12614 TLQDMGTYVVMVGAARAAAHLTVIE 12638
Score = 54.3 bits (129), Expect = 7e-07
Identities = 31/96 (32%), Positives = 42/96 (43%)
Query: 1179 EAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTL 1238
E P Q L +V +G A C + G P+PKISW+K L + + TL
Sbjct: 3237 EPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTL 3296
Query: 1239 EIRKPCPFDGGIYVCRATNLQGEARCECRLEVRVPQ 1274
+ + P D +Y C A N G A L V VP+
Sbjct: 3297 LLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPE 3332
Score = 54.3 bits (129), Expect = 7e-07
Identities = 111/523 (21%), Positives = 174/523 (33%), Gaps = 88/523 (16%)
Query: 316 PAEEDVWEILRQAPPSEYERIAFQYGVTDLRGMLKRLKGMRRD-------EKKSTAFQKK 368
PAEE + R++P E R V+ R + + + R D K + QK
Sbjct: 32296 PAEEYEDDTERRSPTPERTRPRSPSPVSSERSLSRFERSARFDIFSRYESMKAALKTQKT 32355
Query: 369 LEPAYQV------SKGHKIRLTVELADH------------------DAEVKWLKNGQEIQ 404
E Y+V + H R+T+ + H AEVKW NG E+Q
Sbjct: 32356 SERKYEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQ 32415
Query: 405 MSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCSTELFV--------------- 449
S SK + + TL I C D Y+ V K +
Sbjct: 32416 ES-SKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQ 32474
Query: 450 ---KEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKKD 506
+E P + L + E+ E + V+ +K + TRE Y
Sbjct: 32475 RRDEEVPRSVFPELTRTEAYAVSSFKKTSEM-EASSSVREVKSQMTETRESLSSYEHSAS 32533
Query: 507 GQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFKC 566
+ + E LE+ + A ++ + + + VY+ + A F C
Sbjct: 32534 AEMKSAALEEKSLEEKSTTRKIKT--TLAARILTKPRSMTVYEG---------ESARFSC 32582
Query: 567 EVSDENVRGV-WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNL 625
+ E V V WL+ G+ L +R +V+ I V +DE +YS V E
Sbjct: 32583 DTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQ 32642
Query: 626 SA-------KLHFMEVKIDFVPRQEPPKIHLDCPGRI--PDTIVVVAGNKLRLDVPISGD 676
A K E + PR + P+ + P + P + + + P
Sbjct: 32643 EAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETK 32702
Query: 677 PAPT-------VIWQKAITQGNKAPARP-------APDAPEDTGDSDEWVFDKKLLCETE 722
P PT V ITQ KA A ++ W D K L E
Sbjct: 32703 PTPTEKVQHLPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKE-N 32761
Query: 723 GRVRVETTKDRSI-FTVEGAEKEDEGVYTVTVKNPVGEDQVNL 764
G + + D + + + D+G Y + G + NL
Sbjct: 32762 GHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNL 32804
Score = 53.5 bits (127), Expect = 1e-06
Identities = 93/427 (21%), Positives = 144/427 (33%), Gaps = 76/427 (17%)
Query: 376 SKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQ 435
S+G R ++ D +V W ++I+ S + L I++ D+ Y
Sbjct: 3357 SEGQPARFQCRVSGTDLKVSWYSKDKKIKPSRF-FRMTQFEDTYQLEIAEAYPEDEGTYT 3415
Query: 436 CVVG---GEKCST--------------------ELFVKEPPVLITRPLEDQLVMVGQRVE 472
V G+ ST E+ +K PV I R +E V +G +
Sbjct: 3416 FVASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKAAPV-IKRKIEPLEVALGHLAK 3474
Query: 473 FECEV-SEEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSG 531
F CE+ S + +W K G E+ + R K L I + D G Y S
Sbjct: 3475 FTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSK--YISSLEILRTQVVDCGEYTCKASN 3532
Query: 532 G----QALAELIVQEKKLEVYQSIA-DLMVGAKDQAVFKCEVSDENV-RGVWLKNGKELV 585
A L V E + S L A F C V+ V +W K+G L
Sbjct: 3533 EYGSVSCTATLTVTEAYPPTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALS 3592
Query: 586 PDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPP 645
P ++S H L + ++T D YS C S K + + + +P
Sbjct: 3593 PSPNWRISDAENKHILELSNLTIQDRGVYS-------CKASNKFGADICQAELIIIDKPH 3645
Query: 646 KIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDT 705
I + + + K+ L+ + D TV W K G K P
Sbjct: 3646 FI------KELEPVQSAINKKVHLECQVDEDRKVTVTWSK---DGQKLP----------P 3686
Query: 706 GDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLT 765
G + F+ K+ + + A+ +D G Y T N G + T
Sbjct: 3687 GKDYKICFEDKI----------------ATLEIPLAKLKDSGTYVCTASNEAGSSSCSAT 3730
Query: 766 VKVIDVP 772
V V + P
Sbjct: 3731 VTVREPP 3737
Score = 53.1 bits (126), Expect = 2e-06
Identities = 31/104 (29%), Positives = 46/104 (44%)
Query: 1167 YEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDAR 1226
YE + + AP T + + V G V+ P ++ W+ NG++L E ++
Sbjct: 32360 YEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSK 32419
Query: 1227 FRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
+ GVLTLEI D G Y TN +GEA L+V
Sbjct: 32420 IHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDV 32463
Score = 52.8 bits (125), Expect = 2e-06
Identities = 150/740 (20%), Positives = 256/740 (34%), Gaps = 107/740 (14%)
Query: 12 FSKKPRSVEVAAGSPAVFEAE-TERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVRE 70
F +P+S+ G A F T ++ WQ+ G+ +S S + ++ +H L +
Sbjct: 3553 FLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSPSPNWRISDAENKHILELSN 3612
Query: 71 VGPADQGSYAVIAGSSKVKFDLKVIEAEKA---EPMLAPAPAPAEA-----------TGA 116
+ D+G Y+ A + KF + +AE +P P ++
Sbjct: 3613 LTIQDRGVYSCKASN---KFGADICQAELIIIDKPHFIKELEPVQSAINKKVHLECQVDE 3669
Query: 117 PGEAPAPAAELGESAPSPKG------SSSAALNGPTPGAPDDPIGLFVMRPQDGEVTVGG 170
+ ++ G+ P K A L P D + + G +
Sbjct: 3670 DRKVTVTWSKDGQKLPPGKDYKICFEDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSA 3729
Query: 171 SIT------FSARVAGASLLKP-------------PVVK--WFK-GKWVDLSSKVGQHLQ 208
++T F +V + L+ P PV++ WFK K + S+ V +
Sbjct: 3730 TVTVREPPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTWFKNNKELSESNTVRMYFV 3789
Query: 209 LHDSYDRASKVYLFELHITDAQPAFTGSYRCEVSTKDKFDCSNFNLTVHEAMGTGDLDLL 268
++ L ITD + +GSY CE D + + + E +
Sbjct: 3790 NSEAI----------LDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKEPP-----SFI 3834
Query: 269 SAFRRTSLAGGGRRISDSH-EDTGILDFSSLLKKRDSFRTPRDSKLEAPAEEDVWEI--L 325
+ G + TG + S K + R+ + +L + EI
Sbjct: 3835 KTLEPADIVRGTNALLQCEVSGTGPFEI-SWFKDKKQIRSSKKYRLFSQKSLVCLEIFSF 3893
Query: 326 RQAPPSEYERIAFQYGVTDLRGMLKRLKGMRRDEKKSTAFQKKLEPAYQVSKGHKIRLTV 385
A EYE + V M L K+ F KK++ + G + L
Sbjct: 3894 NSADVGEYECVVAN-EVGKCGCMATHLL------KEPPTFVKKVDDLIALG-GQTVTLQA 3945
Query: 386 EL-ADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCV----VGG 440
+ V W+K GQE+ K L I ++ Y C+ G
Sbjct: 3946 AVRGSEPISVTWMK-GQEVIREDGKIKMSFSNGVAVLIIPDVQISFGGKYTCLAENEAGS 4004
Query: 441 EKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVS-EEGAQVKWLKDGVELTREETF 499
+ EL VKEP +I R E V G E V+ + KW KDG L + +
Sbjct: 4005 QTSVGELIVKEPAKIIER-AELIQVTAGDPATLEYTVAGTPELKPKWYKDGRPLVASKKY 4063
Query: 500 KYRFKKDGQRHHLIINEAMLEDAGHYALCTSG--GQALAE--LIVQEKKLEVY--QSIAD 553
+ FK + + L A L D+G Y S G + E V ++ + + + + +
Sbjct: 4064 RISFKNNVAQ--LKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLDRDIAPFFTKPLRN 4121
Query: 554 LMVGAKDQAVFKCEVSDE-NVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEA 612
+ C+++ +R W K+GKE+ R +++ + L I V D
Sbjct: 4122 VDSVVNGTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVEGTASLEIIRVDMNDAG 4181
Query: 613 DYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVP 672
+ F C + + + + QEPP P + V+ G+ + L
Sbjct: 4182 N-------FTCRATNSVGSKDSSGALIV-QEPPSFVTK-----PGSKDVLPGSAVCLKST 4228
Query: 673 ISGDPAPTVIWQKAITQGNK 692
G T+ W K GNK
Sbjct: 4229 FQGSTPLTIRWFK----GNK 4244
Score = 52.8 bits (125), Expect = 2e-06
Identities = 28/90 (31%), Positives = 42/90 (46%)
Query: 6 KKPVSAFSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHT 65
K+P F+K V G+ AV E E R KV+W + G++I S KY + +G
Sbjct: 12281 KEPPVEFTKPLEDQTVEEGATAVLECEVSRENAKVKWFKNGTEILKSKKYEIVADGRVRK 12340
Query: 66 LTVREVGPADQGSYAVIAGSSKVKFDLKVI 95
L + + P D +Y A K +L V+
Sbjct: 12341 LVIHDCTPEDIKTYTCDAKDFKTSCNLNVV 12370
Score = 52.4 bits (124), Expect = 3e-06
Identities = 52/164 (31%), Positives = 74/164 (45%), Gaps = 17/164 (10%)
Query: 378 GHKIRLTVELADH-DAEVKWLKNGQEIQMSGS--KYIFESIGAKRTLTISQCSLADDAAY 434
G +R V + H + V W K+GQ+I+ + KY FES LTI+ + DDA Y
Sbjct: 31704 GENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEY 31763
Query: 435 QCVV----GGEKCSTELFV--KEPPVLIT-RPLEDQLV-----MVGQRVEFECEVSE-EG 481
V G + C +L V PP T RP+ +L+ GQ V FE VS
Sbjct: 31764 TVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPP 31823
Query: 482 AQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHY 525
+KW KDG L+ + + + L I + + ED G+Y
Sbjct: 31824 PTLKWEKDGQPLSLGPNIEI-IHEGLDYYALHIRDTLPEDTGYY 31866
Score = 52.0 bits (123), Expect = 4e-06
Identities = 26/86 (30%), Positives = 45/86 (52%)
Query: 14 KKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGP 73
+ P+ + A G+ VF AE + V+V+W R + +K+ + +EG H L + ++ P
Sbjct: 12916 RPPQDILEAPGADVVFLAELNKDKVEVQWLRNNMVVVQGDKHQMMSEGKIHRLQICDIKP 12975
Query: 74 ADQGSYAVIAGSSKVKFDLKVIEAEK 99
DQG Y IA + + L++ A K
Sbjct: 12976 RDQGEYRFIAKDKEARAKLELAAAPK 13001
Score = 51.6 bits (122), Expect = 5e-06
Identities = 28/91 (30%), Positives = 42/91 (46%)
Query: 1181 PSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEI 1240
P F Q L +V G L C V+GS +I W K G ++ R G LE+
Sbjct: 8346 PVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFSFASGTAVLEL 8405
Query: 1241 RKPCPFDGGIYVCRATNLQGEARCECRLEVR 1271
R D G YVC+A+N+ G + ++ ++
Sbjct: 8406 RDVAKADSGDYVCKASNVAGSDTTKSKVTIK 8436
Score = 50.8 bits (120), Expect = 8e-06
Identities = 51/207 (24%), Positives = 78/207 (37%), Gaps = 17/207 (8%)
Query: 1055 KATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGY-TVQKADKKTMEWF 1113
K L + +P PP+ L VT+ + L W PP G ++ GY T + +++ + +
Sbjct: 18788 KPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRW 18847
Query: 1114 TVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYK 1173
T + VV L G Y FRV ++N VG S +PR Y+
Sbjct: 18848 TEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVS-----------LPREAEGV----YE 18892
Query: 1174 ALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQ 1233
A + P P ++ AG + V G P P W K ++ + +
Sbjct: 18893 AKEQLLPPKILMP-EQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKAD 18951
Query: 1234 GVLTLEIRKPCPFDGGIYVCRATNLQG 1260
L I+ D G Y A N G
Sbjct: 18952 SSSILIIKDVTRKDSGYYSLTAENSSG 18978
Score = 50.4 bits (119), Expect = 1e-05
Identities = 22/81 (27%), Positives = 39/81 (48%)
Query: 17 RSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQ 76
+ +E F + R V ++W + G ++ N+ + +H LT+++ G D+
Sbjct: 12741 KDIETMEKKSVTFWCKVNRLNVTLKWTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGFPDE 12800
Query: 77 GSYAVIAGSSKVKFDLKVIEA 97
G Y V AG K +L +IEA
Sbjct: 12801 GEYIVTAGQDKSVAELLIIEA 12821
Score = 50.1 bits (118), Expect = 1e-05
Identities = 53/164 (32%), Positives = 80/164 (48%), Gaps = 20/164 (12%)
Query: 393 EVKWLKNGQEIQMS---GSKYIFESIGAKRTLTISQCSLADDAAYQCVV---GGEKCST- 445
EV W ++GQ I S G + F AK LTI + A+ Y G+ ST
Sbjct: 36 EVSWFRDGQVISTSTLPGVQISFSDGRAK--LTIPAVTKANSGRYSLKATNGSGQATSTA 93
Query: 446 ELFVKE---PPVLITRPLEDQLVMVGQRVEFECEVSEEGAQV-KWLKDGVELTREETFKY 501
EL VK PP + R L+ V G +V + V+ V K+ +DG E+ + + +
Sbjct: 94 ELLVKAETAPPNFVQR-LQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEI--QSSLDF 150
Query: 502 RFKKDGQRHHLIINEAMLEDAGHYAL--CTSGGQA--LAELIVQ 541
+ ++G + L+I EA ED+G Y++ S G+A AEL+VQ
Sbjct: 151 QISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194
Score = 50.1 bits (118), Expect = 1e-05
Identities = 129/664 (19%), Positives = 223/664 (33%), Gaps = 104/664 (15%)
Query: 131 APSPKGSSSAALNGPTPGAPDDPIGLFVMRPQDGEVTVGGSITFSARVAGASLLKPPVVK 190
A +P GS+S + P +F P E ++ ++G P V
Sbjct: 5498 AQNPAGSTSCSTKVIVKEPP-----VFSSFPPIVETLKNAEVSLECELSGTP---PFEVV 5549
Query: 191 WFKGKWVDLSSKVGQHLQLHDSYDRASKVYLFELHITDAQPAFTGSYRCEVSTKDKFDCS 250
W+K K SSK Y ASK + +HI + + G Y C+ + D
Sbjct: 5550 WYKDKRQLRSSK---------KYKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVGSDTC 5600
Query: 251 NFNLTVHE-AMGTGDLDLLSAFRRTSLAGGGRRISDSHEDTGILDFSSLLKKRDSFRTPR 309
+ + E L+ L T +AG + S E + L +K + R
Sbjct: 5601 VCTVKLKEPPRFVSKLNSL-----TVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRESE 5655
Query: 310 DSKLEAPAEEDVWEILRQAPPSEYERIAFQYGVTDLRGMLKRLKGMRRDEKKSTAFQKKL 369
+ ++ + + P + + I +K GMR ++ A L
Sbjct: 5656 NIRITFVENVATLQFAKAEPANAGKYIC----------QIKNDGGMR----ENMATLMVL 5701
Query: 370 EPAYQVSKGHKIRLTV---------ELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRT 420
EPA V K + +TV + V+W K+G ++ S K+ F +
Sbjct: 5702 EPAVIVEKAGPMTVTVGETCTLECKVAGTPELSVEWYKDG-KLLTSSQKHKFSFYNKISS 5760
Query: 421 LTISQCSLADDAAY----QCVVGGEKCSTELFVKE--PPVLITRPLEDQLVMVGQRVEFE 474
L I D Y Q VG C+ + V + P TR L++ ++G E
Sbjct: 5761 LRILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSDRAVPPSFTRRLKNTGGVLGASCILE 5820
Query: 475 CEVS-EEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHY----ALCT 529
C+V+ V W + ++ ++ F + L +N D G+Y A
Sbjct: 5821 CKVAGSSPISVAWFHEKTKIVSGAKYQTTFSDNVCT--LQLNSLDSSDMGNYTCVAANVA 5878
Query: 530 SGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSR 589
+ A L VQE V + ++ K+ + W + +ELV R
Sbjct: 5879 GSDECRAVLTVQEPPSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGARELVKGDR 5938
Query: 590 IKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLH-FMEVKIDFVPRQEPPKIH 648
+ V +L + ++ + +Y+ V A S F++ F+ R +
Sbjct: 5939 CNIYFEDTVAELELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKEPAAFLKRLSDHSVE 5998
Query: 649 LDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDS 708
G + L+ +G +V W+K D T
Sbjct: 5999 --------------PGKSIILESTYTGTLPISVTWKK--------------DGFNIT--- 6027
Query: 709 DEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKV 768
T + + TT+ I + + K D G Y+ ++N G D V
Sbjct: 6028 ------------TSEKCNIVTTEKTCILEILNSTKRDAGQYSCEIENEAGRDVCGALVST 6075
Query: 769 IDVP 772
++ P
Sbjct: 6076 LEPP 6079
Score = 49.7 bits (117), Expect = 2e-05
Identities = 54/228 (23%), Positives = 83/228 (36%), Gaps = 35/228 (15%)
Query: 1058 LVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLE 1117
L + + P+ P+ L T+ + L+WK P+ G + + GY ++K ++ E
Sbjct: 15287 LAVDPLGPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDF----E 15342
Query: 1118 HYRRTHCVVPELIIGN-----GYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNY 1172
+ C ++ N Y FRV + N +G S+ + P N
Sbjct: 15343 RVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSL----------------PLNV 15386
Query: 1173 KALDFSEAPSFTQPLVNRS----VIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFR 1228
D P+ L R V AG + V G P PKI W KN + +
Sbjct: 15387 VIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDAL 15446
Query: 1229 MFSKQGV------LTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
+K+ V L I K D G Y A+N G +EV
Sbjct: 15447 QITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEV 15494
Score = 49.7 bits (117), Expect = 2e-05
Identities = 24/94 (25%), Positives = 40/94 (42%)
Query: 1178 SEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLT 1237
S P L + +V + A G P+P W K+G + + ++++ +G
Sbjct: 32849 SSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFF 32908
Query: 1238 LEIRKPCPFDGGIYVCRATNLQGEARCECRLEVR 1271
LEI K D G+Y C N G C+L ++
Sbjct: 32909 LEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIK 32942
Score = 48.5 bits (114), Expect = 4e-05
Identities = 24/81 (29%), Positives = 37/81 (45%)
Query: 14 KKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGP 73
KKP+ V + FE V V+W +I S+K+ L +E H L ++ + P
Sbjct: 2799 KKPKDVTALENATVAFEVSVSHDTVPVKWFHKSVEIKPSDKHRLVSERKVHKLMLQNISP 2858
Query: 74 ADQGSYAVIAGSSKVKFDLKV 94
+D G Y + G + K L V
Sbjct: 2859 SDAGEYTAVVGQLECKAKLFV 2879
Score = 48.1 bits (113), Expect = 5e-05
Identities = 30/96 (31%), Positives = 47/96 (48%), Gaps = 2/96 (2%)
Query: 1178 SEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDA--RFRMFSKQGV 1235
++AP+FTQPL + V+ G TA + G P P++SWF++G + ++ G
Sbjct: 3 TQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGR 62
Query: 1236 LTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVR 1271
L I + G Y +ATN G+A L V+
Sbjct: 63 AKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98
Score = 48.1 bits (113), Expect = 5e-05
Identities = 54/233 (23%), Positives = 91/233 (39%), Gaps = 50/233 (21%)
Query: 545 LEVYQSIADLMVGAKD----QAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHK 600
L+ + I D+++ + A+F+C VS W+K+G + + + G+ K
Sbjct: 11115 LKFVKEIKDIILTESEFVGSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIADGKDRK 11174
Query: 601 LTIDDVTPADEADYSFVPE--GFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDT 658
L I DV +D +Y+ V +AKL E+ + FV E +
Sbjct: 11175 LHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEELPVRFVKTLE-------------EE 11221
Query: 659 IVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLL 718
+ VV G L L ++ + V+W+K D K++
Sbjct: 11222 VTVVKGQPLYLSCELNKE--RDVVWRK----------------------------DGKIV 11251
Query: 719 CETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDV 771
E GR+ T+ A+ D G YTVTV+N + + VKV++V
Sbjct: 11252 VEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVEN-ANNLECSSCVKVVEV 11303
Score = 47.8 bits (112), Expect = 7e-05
Identities = 26/93 (27%), Positives = 41/93 (44%), Gaps = 3/93 (3%)
Query: 1181 PSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDL---GEDARFRMFSKQGVLT 1237
P FT PL N++ G + P+P ++W+K+G + D ++ S +G+
Sbjct: 31690 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQ 31749
Query: 1238 LEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
L I D Y A N GE C+ +L V
Sbjct: 31750 LTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV 31782
Score = 45.8 bits (107), Expect = 3e-04
Identities = 22/82 (26%), Positives = 35/82 (42%)
Query: 13 SKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVG 72
+K +++EV A FE E V W + G +I S K+ + +G H L +
Sbjct: 2885 TKTMKNIEVPETKTASFECEVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTS 2944
Query: 73 PADQGSYAVIAGSSKVKFDLKV 94
D Y + G+ +V L V
Sbjct: 2945 TEDSAEYTFVCGNDQVSATLTV 2966
Score = 45.1 bits (105), Expect = 4e-04
Identities = 27/80 (33%), Positives = 37/80 (46%)
Query: 17 RSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQ 76
+ V V AG A F+ E + V W G + S+K +EG HTLT+R+V D
Sbjct: 12203 KDVTVTAGETATFDCELSYEDIPVEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLEDA 12262
Query: 77 GSYAVIAGSSKVKFDLKVIE 96
G + A K +L V E
Sbjct: 12263 GEVQLTAKDFKTHANLFVKE 12282
Score = 45.1 bits (105), Expect = 4e-04
Identities = 29/91 (31%), Positives = 44/91 (48%), Gaps = 5/91 (5%)
Query: 1183 FTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRK 1242
FT+PL +++V G TA+L C V K+ WFKNG ++ + ++ + + V L I
Sbjct: 12287 FTKPLEDQTVEEGATAVLECEV-SRENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHD 12345
Query: 1243 PCPFDGGIYVCRATNLQGEARCECRLEVRVP 1273
P D Y C A + + C L V P
Sbjct: 12346 CTPEDIKTYTCDAKDF----KTSCNLNVVPP 12372
Score = 44.7 bits (104), Expect = 6e-04
Identities = 33/108 (30%), Positives = 43/108 (39%), Gaps = 6/108 (5%)
Query: 1165 ITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNG--LDLG 1222
+T PP D + P F + L N G + V G P P + W K+G L LG
Sbjct: 31782 VTLHPP---PTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLG 31838
Query: 1223 EDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
+ + L IR P D G Y ATN G C+ L+V
Sbjct: 31839 PNIEI-IHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQV 31885
Score = 44.7 bits (104), Expect = 6e-04
Identities = 48/223 (21%), Positives = 85/223 (38%), Gaps = 8/223 (3%)
Query: 558 AKDQAVFKCEVSDENVRG---VWLKNGKELVPDSRIKVSHIGR-VHKLTIDDVTPADEAD 613
+K+ A C V +R W K+GK+L + + + ++L I+++T +D+ +
Sbjct: 32729 SKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGE 32788
Query: 614 YSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPI 673
Y G L FM + + + V + + PI
Sbjct: 32789 YVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPI 32848
Query: 674 SGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDR 733
S P V + T + + A+ A A + + W D K + + G+ ++ K
Sbjct: 32849 SSKPV-IVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQG-GKYKLSEDKGG 32906
Query: 734 SIFTVEGAEKEDEGVYTVTVKNPVG--EDQVNLTVKVIDVPDA 774
+ + D G+YT TVKN G LT+K I +A
Sbjct: 32907 FFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEA 32949
Score = 44.3 bits (103), Expect = 8e-04
Identities = 26/91 (28%), Positives = 43/91 (47%)
Query: 1181 PSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEI 1240
P+F Q L + +V G L V G P P + ++++G ++ F++ + + +L I
Sbjct: 104 PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLI 163
Query: 1241 RKPCPFDGGIYVCRATNLQGEARCECRLEVR 1271
+ P D G Y ATN G A L V+
Sbjct: 164 AEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194
Score = 44.3 bits (103), Expect = 8e-04
Identities = 29/108 (26%), Positives = 49/108 (45%), Gaps = 16/108 (14%)
Query: 10 SAFSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVR 69
+ F+K ++EV+ E + G +V W +G +I + +Y + TEG + L ++
Sbjct: 12463 AVFTKNLANIEVSETDTIKLVCEVSKPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQ 12522
Query: 70 EVGPADQGSYAVIAGSS----KVKF------------DLKVIEAEKAE 101
D G+Y SS KVK +L+++E EKAE
Sbjct: 12523 NAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLEILEGEKAE 12570
Score = 43.5 bits (101), Expect = 0.001
Identities = 23/76 (30%), Positives = 35/76 (46%)
Query: 28 VFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYAVIAGSSK 87
VFE E +G+ V W +I S+KY + G + LTV + D+G Y AG +
Sbjct: 2551 VFEVELSHSGIDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTFYAGENM 2610
Query: 88 VKFDLKVIEAEKAEPM 103
L V ++P+
Sbjct: 2611 TSGKLTVAGGAISKPL 2626
Score = 42.0 bits (97), Expect = 0.004
Identities = 33/111 (29%), Positives = 51/111 (45%), Gaps = 14/111 (12%)
Query: 453 PVLITRPLEDQLVMVGQRVEFECEVS-EEGAQVKWLKDGVELTREETFKYRFKKDGQRHH 511
P IT+P+ +LV G V F C+V V W K GV LT +K + K
Sbjct: 1082 PYFITKPVVQKLVEGGS-VVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECK 1140
Query: 512 LIINEAMLEDAGHYALC-------TSGGQALA-----ELIVQEKKLEVYQS 550
L+I+ +DAG Y + TS +L EL+++ ++ +YQ+
Sbjct: 1141 LVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLMKSQQEMLYQT 1191
Score = 41.6 bits (96), Expect = 0.005
Identities = 21/86 (24%), Positives = 38/86 (44%)
Query: 9 VSAFSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTV 68
V F K+ + +EV E ++ +W ++ ++ KY + + R LTV
Sbjct: 2266 VVEFVKELQDIEVPESYSGELECIVSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTV 2325
Query: 69 REVGPADQGSYAVIAGSSKVKFDLKV 94
++V DQG Y+ + K LK+
Sbjct: 2326 KDVTKEDQGEYSFVIDGKKTTCKLKM 2351
Score = 41.6 bits (96), Expect = 0.005
Identities = 26/94 (27%), Positives = 38/94 (40%), Gaps = 1/94 (1%)
Query: 1181 PSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEI 1240
P+ PL + G A C V G+ K+SW+ + FRM + LEI
Sbjct: 3345 PAIITPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEI 3403
Query: 1241 RKPCPFDGGIYVCRATNLQGEARCECRLEVRVPQ 1274
+ P D G Y A+N G+ L + P+
Sbjct: 3404 AEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPE 3437
Score = 41.2 bits (95), Expect = 0.006
Identities = 23/105 (21%), Positives = 46/105 (43%), Gaps = 16/105 (15%)
Query: 12 FSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREV 71
F K + ++V A+FE E + V+W + ++ +++ + E H L +
Sbjct: 3060 FRKHIKDIKVLEKKRAMFECEVSEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPST 3119
Query: 72 GPADQGSYAVIAGSS----------------KVKFDLKVIEAEKA 100
+D G Y V+AG + +K +++VIE ++A
Sbjct: 3120 RMSDAGKYTVVAGGNVSTAKLFVEGRDVRIRSIKKEVQVIEKQRA 3164
Score = 41.2 bits (95), Expect = 0.006
Identities = 23/91 (25%), Positives = 41/91 (45%)
Query: 8 PVSAFSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLT 67
P F + ++V A FE E R KV+W + G++I KY + ++G L
Sbjct: 12372 PHVEFLRPLTDLQVREKEMARFECELSRENAKVKWFKDGAEIKKGKKYDIISKGAVRILV 12431
Query: 68 VREVGPADQGSYAVIAGSSKVKFDLKVIEAE 98
+ + D+ Y+ +++ L V+E E
Sbjct: 12432 INKCLLDDEAEYSCEVRTARTSGMLTVLEEE 12462
Score = 40.8 bits (94), Expect = 0.008
Identities = 38/167 (22%), Positives = 69/167 (41%), Gaps = 8/167 (4%)
Query: 457 TRPLEDQLVMVGQRVEFECEVSE-EGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIIN 515
T+PL+ +V+ G FE +S +V W +DG ++ + R L I
Sbjct: 9 TQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIP 68
Query: 516 EAMLEDAGHYALCTSGGQ----ALAELIVQEKKL--EVYQSIADLMVGAKDQAVFKCEVS 569
++G Y+L + G + AEL+V+ + Q + + V Q + V+
Sbjct: 69 AVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVT 128
Query: 570 DENVRGV-WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYS 615
V + ++G E+ ++S G ++ L I + P D YS
Sbjct: 129 GIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYS 175
Score = 40.8 bits (94), Expect = 0.008
Identities = 21/70 (30%), Positives = 36/70 (51%), Gaps = 1/70 (1%)
Query: 27 AVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYA-VIAGS 85
A FE ET VKV+W + G ++ +KY + ++ H L++ + +D Y+ V+
Sbjct: 2192 ATFECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVED 2251
Query: 86 SKVKFDLKVI 95
VK K+I
Sbjct: 2252 ENVKTTAKLI 2261
Score = 40.8 bits (94), Expect = 0.008
Identities = 29/105 (27%), Positives = 44/105 (41%), Gaps = 9/105 (8%)
Query: 27 AVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYA--VIAG 84
AVF + R V+W R G +I KY +G+ H L +++ D+ YA V
Sbjct: 12840 AVFSCQLSREKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDCRLDDECEYACGVEDR 12899
Query: 85 SSKVKFDLKVIEAEKAEPMLAPAPAPAEATGAPGEAPAPAAELGE 129
S+ + ++ I E P P + APG AEL +
Sbjct: 12900 KSRARLFVEEIPVEIIRP-------PQDILEAPGADVVFLAELNK 12937
Score = 40.8 bits (94), Expect = 0.008
Identities = 24/80 (30%), Positives = 38/80 (47%), Gaps = 1/80 (1%)
Query: 40 VRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYAVIAGSSKVKFDLKVIEAEK 99
++W R G ++ S KY ++++G HTLTV D+G Y IA + + + +
Sbjct: 30564 IKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQ 30623
Query: 100 AEPMLAPA-PAPAEATGAPG 118
A P P P + GA G
Sbjct: 30624 ATPQFHPGYPLKEKYYGAVG 30643
Score = 40.8 bits (94), Expect = 0.008
Identities = 69/326 (21%), Positives = 130/326 (39%), Gaps = 64/326 (19%)
Query: 478 SEEGAQVKWLKDGVELTREE---TFKYR------FKKDGQRHHLIINEAMLEDAGHYALC 528
+ E Q WLK +E + T K+R KKD +++++ A + G A+
Sbjct: 31496 ASEALQHPWLKQKIERVSTKVIRTLKHRRYYHTLIKKD---LNMVVSAARISCGG--AIR 31550
Query: 529 TSGGQALAELIVQEKKL-----EVYQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKE 583
+ G ++A++ V ++ ++ ++ + G + V K E D++ + W ++
Sbjct: 31551 SQKGVSVAKVKVASIEIGPVSGQIMHAVGE--EGGHVKYVCKIENYDQSTQVTWYFGVRQ 31608
Query: 584 LVPDSRIKVSHIGRVHKLTIDDVTPADEADY--SFVPEGFACNLSAKLHFMEVK--IDFV 639
L + ++++ V L + D+T D+ Y V + + A+L V+ D+
Sbjct: 31609 LENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFVKGVREVYDYY 31668
Query: 640 PRQEPPKIH--------LDCPGRIPDTI---VVVAGNKLRLDVPISGDPAPTVIWQKAIT 688
R+ KI L+ P + G +R V I+ P P V W K+
Sbjct: 31669 CRRTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKS-- 31726
Query: 689 QGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGV 748
G K +P + + T +SD+ ++ T+ +D+
Sbjct: 31727 -GQKI--KPGDNDKKYTFESDKGLYQ---------------------LTINSVTTDDDAE 31762
Query: 749 YTVTVKNPVGED--QVNLTVKVIDVP 772
YTV +N GED + LTV + P
Sbjct: 31763 YTVVARNKYGEDSCKAKLTVTLHPPP 31788
Score = 40.4 bits (93), Expect = 0.011
Identities = 18/57 (31%), Positives = 30/57 (52%)
Query: 38 VKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYAVIAGSSKVKFDLKV 94
V V+W + G +I S KY + +G R L +++ D+G Y G+ K K ++ V
Sbjct: 11690 VPVKWFKDGEEIVPSPKYSIKADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTV 11746
Score = 40.4 bits (93), Expect = 0.011
Identities = 17/61 (27%), Positives = 31/61 (50%)
Query: 19 VEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGS 78
V+V A FE E R RW +G +I+ +++ L +GT+H++ ++ D+
Sbjct: 11849 VKVFEKDEAKFECEVSREPKTFRWLKGTQEITGDDRFELIKDGTKHSMVIKSAAFEDEAK 11908
Query: 79 Y 79
Y
Sbjct: 11909 Y 11909
Score = 39.7 bits (91), Expect = 0.019
Identities = 46/199 (23%), Positives = 87/199 (43%), Gaps = 20/199 (10%)
Query: 453 PVLITRPLEDQLVMVGQRVEFECEV-SEEGAQVKWLKDGVELTREETFKYRFKKDGQRHH 511
PV + +P+ + + GQ F+ +V + W DG ++ + T K K+DG +
Sbjct: 1457 PVFVLKPVSFKC-LEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQ-S 1514
Query: 512 LIINEAMLEDAGHYALCT---SGGQALAELI-VQEKKLEVYQSIADLM--VGAKDQAVFK 565
LII A D+G + + +G +++ ++ V+ + +V + + V K+ + +
Sbjct: 1515 LIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLE 1574
Query: 566 CEV---SDENVRGVWLKNGKELVPDS--RIKVSHIGRVHKLTIDDVTPADEADYSFVPEG 620
+V + N VWLKN +VP +I++ L ID D A Y+
Sbjct: 1575 MKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAIN 1634
Query: 621 FA------CNLSAKLHFME 633
A C ++ ++ F E
Sbjct: 1635 KAGRDTTRCKVNVEVEFAE 1653
Score = 39.7 bits (91), Expect = 0.019
Identities = 25/98 (25%), Positives = 45/98 (45%), Gaps = 1/98 (1%)
Query: 1177 FSEAPS-FTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGV 1235
+ +AP+ F + L + S+ G +L G+P ++W KNG+++ R + + +
Sbjct: 7863 YIKAPAKFVKRLNDYSIEKGKPLILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTEKS 7922
Query: 1236 LTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVRVP 1273
LEI D G Y C N G+ C ++ + P
Sbjct: 7923 AILEIPSSTVEDAGQYNCYIENASGKDSCSAQILILEP 7960
Score = 39.3 bits (90), Expect = 0.024
Identities = 29/94 (30%), Positives = 37/94 (39%), Gaps = 1/94 (1%)
Query: 11 AFSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVRE 70
A SK VA AVFE E K W R G + +N ++G + L +
Sbjct: 2621 AISKPLTDQTVAESQEAVFECEVANPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAA 2680
Query: 71 VGPADQGSYAVIAGSSKVKFDLKVIEAEKAEPML 104
D G Y +SK LKV EA K + L
Sbjct: 2681 TKLDDIGEYTYKVATSKTSAKLKV-EAVKIKKTL 2713
Score = 39.3 bits (90), Expect = 0.024
Identities = 22/88 (25%), Positives = 41/88 (46%), Gaps = 16/88 (18%)
Query: 29 FEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYAVIAGSS-- 86
FE G+ +W + G +I +++K + T+ H+L +R V D Y +AG +
Sbjct: 2988 FEVTVNYEGISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKATS 3047
Query: 87 ---------KVKF-----DLKVIEAEKA 100
++F D+KV+E ++A
Sbjct: 3048 TATLYVEARHIEFRKHIKDIKVLEKKRA 3075
Score = 38.5 bits (88), Expect = 0.041
Identities = 22/81 (27%), Positives = 35/81 (43%)
Query: 1191 SVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGI 1250
+V G +A C G P P ++W + G L AR ++ + + T EI D G
Sbjct: 32571 TVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGN 32630
Query: 1251 YVCRATNLQGEARCECRLEVR 1271
Y N +G+ E L ++
Sbjct: 32631 YSVVVENSEGKQEAEFTLTIQ 32651
Score = 38.1 bits (87), Expect = 0.054
Identities = 29/102 (28%), Positives = 45/102 (44%), Gaps = 9/102 (8%)
Query: 11 AFSKKPRSVEVAAGSPAVFEAETERAG-VKVRWQRGGSDISASNKYGLATEGTRHTLTVR 69
+F++K + +GS V E + + + V W G++IS+ KY LTV
Sbjct: 7683 SFTRKLKETNGLSGSSVVMECKVYGSPPISVSWFHEGNEISSGRKYQTTLTDNTCALTVN 7742
Query: 70 EVGPADQGSYAVI----AGSSKVKFDLKVIE----AEKAEPM 103
+ +D G Y I AGS + L V E +K +PM
Sbjct: 7743 MLEESDSGDYTCIATNMAGSDECSAPLTVREPPSFVQKPDPM 7784
Score = 37.7 bits (86), Expect = 0.071
Identities = 30/109 (27%), Positives = 43/109 (39%), Gaps = 1/109 (0%)
Query: 1163 PGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLG 1222
PG E + L+ P F V+ + G TA V G P P+ WF +G +
Sbjct: 1439 PGRRLEETDESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIV 1498
Query: 1223 EDARFRMFSKQ-GVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
D ++ K+ G +L I P D G + A N G + L V
Sbjct: 1499 NDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTV 1547
Score = 36.6 bits (83), Expect = 0.16
Identities = 20/71 (28%), Positives = 33/71 (46%), Gaps = 3/71 (4%)
Query: 456 ITRPLEDQLVMVGQRVEFECE-VSEEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLII 514
I + ++D +G+ + C+ V +KW + G EL + KY+ DG+ H L +
Sbjct: 30535 IRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSR--KYKMSSDGRTHTLTV 30592
Query: 515 NEAMLEDAGHY 525
ED G Y
Sbjct: 30593 MTEEQEDEGVY 30603
Score = 36.6 bits (83), Expect = 0.16
Identities = 27/92 (29%), Positives = 42/92 (45%), Gaps = 5/92 (5%)
Query: 1175 LDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSP--KPKISWFKNGLDLGEDARFRM-FS 1231
L S P TQ L ++ + A L C V S +++W+K+G L E+ F+ +S
Sbjct: 32712 LPVSAPPKITQFL--KAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYS 32769
Query: 1232 KQGVLTLEIRKPCPFDGGIYVCRATNLQGEAR 1263
G L+I D G YVC + G ++
Sbjct: 32770 ADGTYELKINNLTESDQGEYVCEISGEGGTSK 32801
Score = 36.2 bits (82), Expect = 0.21
Identities = 20/79 (25%), Positives = 34/79 (43%), Gaps = 1/79 (1%)
Query: 17 RSVEVAAGSPAVFEAETERAGV-KVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPAD 75
+ V V G+ AV E + V V+W I ++ +GT+ L + +D
Sbjct: 2452 KDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHASD 2511
Query: 76 QGSYAVIAGSSKVKFDLKV 94
+G Y +I G + +L V
Sbjct: 2512 EGPYKLIVGRVETNCNLSV 2530
Score = 36.2 bits (82), Expect = 0.21
Identities = 55/274 (20%), Positives = 91/274 (33%), Gaps = 66/274 (24%)
Query: 17 RSVEVAAGSPAVFEAETERAGVKVRWQRGGSDIS--ASNKYGLATEGTRHTLTVREVGPA 74
+ V+V AV E E V W + G +I+ ++ E H + + E +
Sbjct: 3154 KEVQVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQS 3213
Query: 75 DQGSYAVIAGSSKVKFDLKVIEAE------KAEPMLAPAPAPAEATGAPGEAPAPAAE-- 126
D G Y +AG ++ L V E + +P+ + PA P P
Sbjct: 3214 DAGEYTFVAGRNRSSVTLYVNAPEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWY 3273
Query: 127 ------------------------LGESAPSPKG---------------SSSAALNGPTP 147
L E+ P S+S ++ P
Sbjct: 3274 KEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEV 3333
Query: 148 GAPDDPIGLF---VMRP-QDGEVTVGGSITFSARVAGASLLKPPVVKWFKGKWVDLSSKV 203
+PD + ++ ++ P QD + G F RV+G L V W+ S+
Sbjct: 3334 VSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDL----KVSWYSKDKKIKPSRF 3389
Query: 204 GQHLQLHDSYDRASKVYLFELHITDAQPAFTGSY 237
+ Q D+Y +L I +A P G+Y
Sbjct: 3390 FRMTQFEDTY---------QLEIAEAYPEDEGTY 3414
Score = 35.8 bits (81), Expect = 0.27
Identities = 19/72 (26%), Positives = 35/72 (48%), Gaps = 1/72 (1%)
Query: 14 KKPRSVEVAAGSPAVFEAETERAGVK-VRWQRGGSDISASNKYGLATEGTRHTLTVREVG 72
K +++ V AVF E VK V+W + G + ++ KY ++ +GT ++L ++
Sbjct: 2711 KTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYSLRIKNCA 2770
Query: 73 PADQGSYAVIAG 84
D+ Y G
Sbjct: 2771 IVDESVYGFRLG 2782
Score = 35.8 bits (81), Expect = 0.27
Identities = 25/95 (26%), Positives = 39/95 (41%)
Query: 1179 EAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTL 1238
E +F + L + SV G +L G+P +SW K+ + + R + + L
Sbjct: 6925 EPATFVKRLADFSVETGSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEKSTIL 6984
Query: 1239 EIRKPCPFDGGIYVCRATNLQGEARCECRLEVRVP 1273
EI + D Y C N G+ CE + V P
Sbjct: 6985 EILESTIEDYAQYSCLIENEAGQDICEALVSVLEP 7019
Score = 35.8 bits (81), Expect = 0.27
Identities = 23/78 (29%), Positives = 35/78 (44%)
Query: 19 VEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGS 78
VEV G A FE E V +W+ G ++AS + +G +H L + G
Sbjct: 11760 VEVFVGETAHFEIELSEPDVHGQWKLKGQPLTASPDCEIIEDGKKHILILHNCQLGMTGE 11819
Query: 79 YAVIAGSSKVKFDLKVIE 96
+ A ++K +LKV E
Sbjct: 11820 VSFQAANAKSAANLKVKE 11837
Score = 35.8 bits (81), Expect = 0.27
Identities = 18/78 (23%), Positives = 36/78 (46%), Gaps = 2/78 (2%)
Query: 28 VFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYAVIAGSSK 87
+ + E +A V+W + G +I S + +G + L +++ +D G Y G+ K
Sbjct: 12036 ILQCEISKADAPVKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTCDCGTDK 12095
Query: 88 V--KFDLKVIEAEKAEPM 103
K D++ E + P+
Sbjct: 12096 TSGKLDIEDREIKLVRPL 12113
Score = 35.8 bits (81), Expect = 0.27
Identities = 27/118 (22%), Positives = 50/118 (42%), Gaps = 19/118 (16%)
Query: 577 WLKNGKELVP---DSRIKVSHIGRVHKLTIDDVTPADEADYSFVP------EGFACNLSA 627
W K+G+++ P D + +++LTI+ VT D+A+Y+ V + L+
Sbjct: 31723 WYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV 31782
Query: 628 KLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQK 685
LH P + + +C G + ++ +SG P PT+ W+K
Sbjct: 31783 TLHPPPTDSTLRPMFKRLLANAECQ----------EGQSVCFEIRVSGIPPPTLKWEK 31830
Score = 35.4 bits (80), Expect = 0.35
Identities = 16/47 (34%), Positives = 30/47 (63%)
Query: 40 VRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYAVIAGSS 86
V++ R G++I +S + ++ EG ++L + E P D G+Y+V A +S
Sbjct: 135 VKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNS 181
Score = 35.4 bits (80), Expect = 0.35
Identities = 45/203 (22%), Positives = 72/203 (35%), Gaps = 60/203 (29%)
Query: 40 VRWQRGGSDISASN---KYGLATEGTRHTLTVREVGPADQGSYAVIAGSSKVKFDLKVIE 96
V W + G I + KY ++ + LT+ V D Y V+A + + +
Sbjct: 31721 VTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGE------D 31774
Query: 97 AEKAEPMLAPAPAPAEATGAPGEAPAPAAELGESAPSPKGSSSAALNGPTPGAPDDPIGL 156
+ KA+ + P P ++T P +
Sbjct: 31775 SCKAKLTVTLHPPPTDSTLRP--------------------------------------M 31796
Query: 157 FVMRPQDGEVTVGGSITFSARVAGASLLKPPVVKWFK-GKWVDLSSKVGQHLQLHDSYDR 215
F + E G S+ F RV+G + PP +KW K G+ + L + +H+ D
Sbjct: 31797 FKRLLANAECQEGQSVCFEIRVSG---IPPPTLKWEKDGQPLSLGPNIEI---IHEGLD- 31849
Query: 216 ASKVYLFELHITDAQPAFTGSYR 238
+ LHI D P TG YR
Sbjct: 31850 -----YYALHIRDTLPEDTGYYR 31867
Score = 35.0 bits (79), Expect = 0.46
Identities = 19/65 (29%), Positives = 28/65 (43%)
Query: 17 RSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQ 76
+ V VF E G K +W R I S+KY + + +TL +R+ DQ
Sbjct: 12647 KDTRVKEQQEVVFNCEVNTEGAKAKWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLDDQ 12706
Query: 77 GSYAV 81
+Y V
Sbjct: 12707 ANYNV 12711
Score = 34.3 bits (77), Expect = 0.78
Identities = 20/85 (23%), Positives = 36/85 (42%), Gaps = 9/85 (10%)
Query: 5 GKKPVSAFSKKPRSVEVAAG--SPAVFEAETERAGVKVR-------WQRGGSDISASNKY 55
GKK KPR + + G V E + + VKV W + G ++ S++
Sbjct: 2342 GKKTTCKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRV 2401
Query: 56 GLATEGTRHTLTVREVGPADQGSYA 80
+ + H L + ++ D G+Y+
Sbjct: 2402 HIVIDKQSHMLLIEDMTKEDAGNYS 2426
Score = 34.3 bits (77), Expect = 0.78
Identities = 24/87 (27%), Positives = 42/87 (48%), Gaps = 4/87 (4%)
Query: 1179 EAPS-FTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLT 1237
EAP+ F + L +++V A+ C + K + W++NG ++ E +++ F K G +
Sbjct: 12820 EAPTEFVEHLEDQTVTEFDDAVFSCQL-SREKANVKWYRNGREIKEGKKYK-FEKDGSIH 12877
Query: 1238 LEIRKPCPFDGGI-YVCRATNLQGEAR 1263
I K C D Y C + + AR
Sbjct: 12878 RLIIKDCRLDDECEYACGVEDRKSRAR 12904
Score = 34.3 bits (77), Expect = 0.78
Identities = 20/65 (30%), Positives = 33/65 (50%), Gaps = 5/65 (7%)
Query: 393 EVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCV----VGGEKCSTELF 448
++KW + G+E+ S KY S G TLT+ D+ Y C+ VG + S++L
Sbjct: 30563 DIKWYRFGKELIQS-RKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLL 30621
Query: 449 VKEPP 453
++ P
Sbjct: 30622 LQATP 30626
Score = 33.9 bits (76), Expect = 1.0
Identities = 24/80 (30%), Positives = 33/80 (41%), Gaps = 2/80 (2%)
Query: 5 GKKPVSAFSKKPRSVEVAAGSPAVFEAE-TERAGVKVRWQRGGSDISASNKYGLATEGTR 63
GK P F + V+ G A FE T +KV W + +I + KY ++
Sbjct: 8149 GKNP-PFFDIRLAPVDAVVGESADFECHVTGTQPIKVSWAKDSREIRSGGKYQISYLENS 8207
Query: 64 HTLTVREVGPADQGSYAVIA 83
LTV +V D G Y A
Sbjct: 8208 AHLTVLKVDKGDSGQYTCYA 8227
Score = 33.9 bits (76), Expect = 1.0
Identities = 17/59 (28%), Positives = 27/59 (45%)
Query: 24 GSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYAVI 82
GS A+FE + W + GS+I S K+ +G L + +V +D G Y +
Sbjct: 11133 GSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYTCV 11191
Score = 33.5 bits (75), Expect = 1.3
Identities = 22/80 (27%), Positives = 34/80 (42%), Gaps = 1/80 (1%)
Query: 7 KPVSAFSKKPRSVEVAAGSPAVFEAE-TERAGVKVRWQRGGSDISASNKYGLATEGTRHT 65
K F ++ + VEV S E E T +V W + +I +S KY L +
Sbjct: 4952 KEPPTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRVSVFN 5011
Query: 66 LTVREVGPADQGSYAVIAGS 85
L + + P+D G Y I +
Sbjct: 5012 LHITKCDPSDTGEYQCIVSN 5031
Score = 33.5 bits (75), Expect = 1.3
Identities = 25/125 (20%), Positives = 50/125 (40%), Gaps = 7/125 (5%)
Query: 16 PRSVEVAAGSPAVFEAETE-RAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPA 74
P + + AG EA + +W++G ++ S+ + + L +++V
Sbjct: 18905 PEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRK 18964
Query: 75 DQGSYAVIAGSSKVKFDLKVIEAEKAEPMLAPAPAPAEATGAPGEAPAPAAELGESAPSP 134
D G Y++ A +S + +K + ++ AP P + + A A L P
Sbjct: 18965 DSGYYSLTAENS------SGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSLSWHIPLE 19018
Query: 135 KGSSS 139
G S+
Sbjct: 19019 DGGSN 19023
Score = 33.1 bits (74), Expect = 1.7
Identities = 53/201 (26%), Positives = 74/201 (36%), Gaps = 44/201 (21%)
Query: 87 KVKFDLKVIEAEKAEPMLAP--APAPAEATGAPGEAPAPAAELGE----------SAPSP 134
K + ++K I+ EP P AP G EA AP E + PSP
Sbjct: 11024 KPEAEVKTIKPPPVEPEPTPIAAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPSP 11083
Query: 135 KGSSSAALNGPTPGA--PDD----------PIGLFVMRPQDGEVT----VGGSITFSARV 178
+ L + G PD+ P+ FV +D +T VG S F V
Sbjct: 11084 IEAERRKLRPGSGGEKPPDEAPFTYQLKAVPLK-FVKEIKDIILTESEFVGSSAIFECLV 11142
Query: 179 AGASLLKPPVVKWFK-GKWVDLSSKVGQHLQLHDSYDRASKVYLFELHITDAQPAFTGSY 237
+ ++ + W K G + S K H + D DR +LHI D Q + G Y
Sbjct: 11143 SPSTA----ITTWMKDGSNIRESPK---HRFIADGKDR-------KLHIIDVQLSDAGEY 11188
Query: 238 RCEVSTKDKFDCSNFNLTVHE 258
C + +K S L V E
Sbjct: 11189 TCVLRLGNKEKTSTAKLVVEE 11209
Score = 33.1 bits (74), Expect = 1.7
Identities = 16/72 (22%), Positives = 31/72 (43%)
Query: 27 AVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYAVIAGSS 86
AVF E ++V+W + + + + EG H++T +++ D V A
Sbjct: 11946 AVFTVELSHDNIRVKWFKNDQRLHTTRSVSMQDEGKTHSITFKDLSIDDTSQIRVEAMGM 12005
Query: 87 KVKFDLKVIEAE 98
+ L V+E +
Sbjct: 12006 SSEAKLTVLEGD 12017
Score = 33.1 bits (74), Expect = 1.7
Identities = 21/84 (25%), Positives = 38/84 (45%), Gaps = 5/84 (5%)
Query: 19 VEVAAGSPAVFEAETE-RAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQG 77
V + AGS V +A + K+ W +G ++ K L G R T ++ +D G
Sbjct: 29057 VTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSG 29116
Query: 78 SYAV----IAGSSKVKFDLKVIEA 97
Y + +G+ V +KV+++
Sbjct: 29117 KYTLTVKNASGTKAVSVMVKVLDS 29140
Score = 32.7 bits (73), Expect = 2.3
Identities = 21/72 (29%), Positives = 35/72 (48%), Gaps = 2/72 (2%)
Query: 460 LEDQLVMVGQRVEFECEVSEEGA-QVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAM 518
+++ ++ G V F C++S ++ W KDG + E ++ F +DG R L I +
Sbjct: 1297 IKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDG-RASLRIPVVL 1355
Query: 519 LEDAGHYALCTS 530
ED G Y S
Sbjct: 1356 PEDEGIYTAFAS 1367
Score = 32.3 bits (72), Expect = 3.0
Identities = 25/89 (28%), Positives = 38/89 (42%), Gaps = 3/89 (3%)
Query: 1181 PSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEI 1240
P++ + L + ++ G T + C P K WF+NG L R + + V L I
Sbjct: 8745 PAWERHLQDVTLKEGQTCTMTCQF-SVPNVKSEWFRNGRILKPQGRHKTEVEHKVHKLTI 8803
Query: 1241 RKPCPFDGGIYVCRATNLQGEARCECRLE 1269
D G Y C+ +L E E R+E
Sbjct: 8804 ADVRAEDQGQYTCKYEDL--ETSAELRIE 8830
Score = 32.3 bits (72), Expect = 3.0
Identities = 22/83 (26%), Positives = 34/83 (40%), Gaps = 1/83 (1%)
Query: 12 FSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREV 71
F+ + V V A FE R V W +G I +S+K+ + +G +H L + +
Sbjct: 11488 FAVPLKDVTVPERRQARFECVLTREA-NVIWSKGPDIIKSSDKFDIIADGKKHILVINDS 11546
Query: 72 GPADQGSYAVIAGSSKVKFDLKV 94
D+G Y K L V
Sbjct: 11547 QFDDEGVYTAEVEGKKTSARLFV 11569
Score = 32.3 bits (72), Expect = 3.0
Identities = 24/67 (35%), Positives = 30/67 (44%), Gaps = 5/67 (7%)
Query: 467 VGQRVEFECEVSEEG---AQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAG 523
V R + + +V +G A V W KDG L +ET + L I EA ED G
Sbjct: 25406 VKAREQLKIDVPFKGRPQATVNWRKDGQTL--KETTRVNVSSSKTVTSLSIKEASKEDVG 25463
Query: 524 HYALCTS 530
Y LC S
Sbjct: 25464 TYELCVS 25470
Score = 32.0 bits (71), Expect = 3.9
Identities = 27/96 (28%), Positives = 39/96 (40%), Gaps = 5/96 (5%)
Query: 7 KPVSAFSKKPRSVEVAAGSPAVFEAETERA-GVKVRWQRGGSDISASNKYGLATEGTRHT 65
K +K +EVA G A F E + A V+ +W + G +I S+K + + +
Sbjct: 3453 KAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISS 3512
Query: 66 LTVREVGPADQGSYAVIA----GSSKVKFDLKVIEA 97
L + D G Y A GS L V EA
Sbjct: 3513 LEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEA 3548
Score = 32.0 bits (71), Expect = 3.9
Identities = 22/76 (28%), Positives = 33/76 (43%), Gaps = 1/76 (1%)
Query: 1179 EAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTL 1238
E FT+ L N V T L C V P ++ W+K ++ E R+ + ++ L
Sbjct: 12461 EEAVFTKNLANIEVSETDTIKLVCEV-SKPGAEVIWYKGDEEIIETGRYEILTEGRKRIL 12519
Query: 1239 EIRKPCPFDGGIYVCR 1254
I+ D G Y CR
Sbjct: 12520 VIQNAHLEDAGNYNCR 12535
Score = 32.0 bits (71), Expect = 3.9
Identities = 22/61 (36%), Positives = 30/61 (49%), Gaps = 2/61 (3%)
Query: 988 GEPVNLLIPFQGKPRPQVTWTKEGQPLA-GEEVSIRNSPTD-TILFIRAARRVHSGTYQV 1045
G+ V I G P P + W K+GQPL+ G + I + D L IR +G Y+V
Sbjct: 31809 GQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRV 31868
Query: 1046 T 1046
T
Sbjct: 31869 T 31869
Score = 31.6 bits (70), Expect = 5.1
Identities = 15/74 (20%), Positives = 34/74 (45%), Gaps = 1/74 (1%)
Query: 7 KPVSAFSKKPRSVEVAAGSPAVFEAE-TERAGVKVRWQRGGSDISASNKYGLATEGTRHT 65
K + +++ S++V G PA + + + + +W + G +++ +KY ++ T
Sbjct: 4576 KEPATITEEAVSIDVTQGDPATLQVKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSI 4635
Query: 66 LTVREVGPADQGSY 79
L + D G Y
Sbjct: 4636 LKIISTEKKDSGEY 4649
Score = 31.6 bits (70), Expect = 5.1
Identities = 25/95 (26%), Positives = 40/95 (42%), Gaps = 15/95 (15%)
Query: 7 KPVSAFSKKPRSVE-VAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHT 65
K V K P ++E V AG+P + KV+W + G I S + ++ E +
Sbjct: 5148 KSVDVTEKDPMTLECVVAGTPEL----------KVKWLKDGKQIVPSRYFSMSFENNVAS 5197
Query: 66 LTVREVGPADQGSYAVIA----GSSKVKFDLKVIE 96
++ V D G Y GSS L+V++
Sbjct: 5198 FRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLD 5232
Score = 31.6 bits (70), Expect = 5.1
Identities = 23/81 (28%), Positives = 33/81 (40%), Gaps = 5/81 (6%)
Query: 21 VAAGSPAVFEAETERAGVKV-RWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSY 79
V AG+ F A V +W GS+I Y + T+ LT++ D G Y
Sbjct: 17522 VKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEY 17581
Query: 80 AV----IAGSSKVKFDLKVIE 96
+ AGS V L V++
Sbjct: 17582 QITVSNAAGSKTVAVHLTVLD 17602
Score = 31.6 bits (70), Expect = 5.1
Identities = 25/107 (23%), Positives = 43/107 (40%), Gaps = 11/107 (10%)
Query: 18 SVEVAAGSPAVFEAETERAGVK-VRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQ 76
++ V AG EA+ + + W RG +I S + + + L V++ D
Sbjct: 23634 TIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDG 23693
Query: 77 GSYAV----IAGSSKVKFDLKVIEAEKAEPMLAPAPAPAEATGAPGE 119
G Y + +AGS ++KV++ P P + TG E
Sbjct: 23694 GQYILRASNVAGSKSFPVNVKVLDRP------GPPEGPVQVTGVTSE 23734
Score = 31.6 bits (70), Expect = 5.1
Identities = 32/96 (33%), Positives = 42/96 (43%), Gaps = 18/96 (18%)
Query: 988 GEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDT----ILFIRAARRVHSGTY 1043
GE G+P P VTW ++GQ L+ S R+ T T I + + G Y
Sbjct: 32575 GESARFSCDTDGEPVPTVTWLRKGQVLS---TSARHQVTTTKYKSTFEISSVQASDEGNY 32631
Query: 1044 QVTVRIENMEDKA----TLVLQ---VVDK--PSPPQ 1070
V V EN E K TL +Q V +K SPP+
Sbjct: 32632 SVVV--ENSEGKQEAEFTLTIQKARVTEKAVTSPPR 32665
Score = 31.2 bits (69), Expect = 6.6
Identities = 20/81 (24%), Positives = 36/81 (44%), Gaps = 2/81 (2%)
Query: 6 KKPVSAFSKKPRSVEVAAGSPAVFEAETERAG-VKVRWQRGGSDISASNKYGLATEGTRH 64
K+P S F K ++ G+ A+ + E G ++ W + I +S KY L ++ +
Sbjct: 3828 KEPPS-FIKTLEPADIVRGTNALLQCEVSGTGPFEISWFKDKKQIRSSKKYRLFSQKSLV 3886
Query: 65 TLTVREVGPADQGSYAVIAGS 85
L + AD G Y + +
Sbjct: 3887 CLEIFSFNSADVGEYECVVAN 3907
Score = 31.2 bits (69), Expect = 6.6
Identities = 20/71 (28%), Positives = 31/71 (43%), Gaps = 1/71 (1%)
Query: 1183 FTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRK 1242
F +PL + V A C + K+ WFK+G ++ + ++ + SK V L I K
Sbjct: 12376 FLRPLTDLQVREKEMARFECEL-SRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINK 12434
Query: 1243 PCPFDGGIYVC 1253
D Y C
Sbjct: 12435 CLLDDEAEYSC 12445
Score = 31.2 bits (69), Expect = 6.6
Identities = 43/175 (24%), Positives = 71/175 (40%), Gaps = 15/175 (8%)
Query: 379 HKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRT-LTISQCSLADDAAYQCV 437
+ + L+ E +HD + L E+Q GS K T TI+ ++ +++
Sbjct: 22063 NSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATCATVKVTEATITGLIQGEEYSFRVS 22122
Query: 438 VGGEKCSTELFVKEPPV----LITRPLEDQL-----VMVGQRVEFECE-VSEEGAQVKWL 487
EK ++ PV L+ P L V+ G+ ++ + + V W
Sbjct: 22123 AQNEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWH 22182
Query: 488 KDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYA--LCTSGGQALAELIV 540
KD V L ++T + + L I +A ED GHY L S G+A+ L V
Sbjct: 22183 KDNVPL--KQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNV 22235
Score = 31.2 bits (69), Expect = 6.6
Identities = 23/87 (26%), Positives = 39/87 (44%), Gaps = 3/87 (3%)
Query: 23 AGSPAVFEAETE-RAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSY-A 80
AGSP + R KV W+ + +++ + T R TLTV++ D G Y
Sbjct: 28661 AGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFL 28720
Query: 81 VIAGSSKVK-FDLKVIEAEKAEPMLAP 106
+ ++ VK F + V+ + P+ P
Sbjct: 28721 TLENTAGVKTFSVTVVVIGRPGPVTGP 28747
Score = 31.2 bits (69), Expect = 6.6
Identities = 31/113 (27%), Positives = 44/113 (38%), Gaps = 8/113 (7%)
Query: 963 TVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPL-AGEEVSI 1021
T++ + + P LP + + VGE V + P P VTW K GQ + G+
Sbjct: 31682 TMRLLERPPEFTLPLYNKTAY---VGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKK 31738
Query: 1022 RNSPTDTILF---IRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQD 1071
+D L+ I + Y V R + ED L V P PP D
Sbjct: 31739 YTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHP-PPTD 31790
Score = 30.8 bits (68), Expect = 8.6
Identities = 20/91 (21%), Positives = 41/91 (45%), Gaps = 4/91 (4%)
Query: 19 VEVAAGSPAVFEAETERAG-VKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQG 77
VE G PA + + + +++ W + + + ++ Y + + +L + +V +D G
Sbjct: 7029 VEAVIGEPATLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVG 7088
Query: 78 SYAVIAGSS---KVKFDLKVIEAEKAEPMLA 105
Y+ A +S + VI+A K P A
Sbjct: 7089 EYSCKADNSVGAVASSAVLVIKARKLPPFFA 7119
Score = 30.8 bits (68), Expect = 8.6
Identities = 20/78 (25%), Positives = 31/78 (39%)
Query: 21 VAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYA 80
V G A F E + V W + + + S +++EG H L ++EV D
Sbjct: 11585 VKEGETATFVCELSHEKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQIK 11644
Query: 81 VIAGSSKVKFDLKVIEAE 98
LKV+EA+
Sbjct: 11645 AQVKELSSTAQLKVLEAD 11662
>gi|110349717 titin isoform novex-2 [Homo sapiens]
Length = 27118
Score = 286 bits (732), Expect = 9e-77
Identities = 238/845 (28%), Positives = 366/845 (43%), Gaps = 77/845 (9%)
Query: 386 ELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCST 445
+L+ A VKW +NG+EI+ G KY FE G+ L I C L D+ Y C V K
Sbjct: 6540 QLSREKANVKWYRNGREIK-EGKKYKFEKDGSIHRLIIKDCRLDDECEYACGVEDRKSRA 6598
Query: 446 ELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKK 505
LFV+E PV I RP +D L G V F E++++ +V+WL++ + + + + K++
Sbjct: 6599 RLFVEEIPVEIIRPPQDILEAPGADVVFLAELNKDKVEVQWLRNNMVVVQGD--KHQMMS 6656
Query: 506 DGQRHHLIINEAMLEDAGHYALCTSGGQALAEL-IVQEKKLEVYQSIADLMVGAKDQAVF 564
+G+ H L I + D G Y +A A+L + K++ + VG V
Sbjct: 6657 EGKIHRLQICDIKPRDQGEYRFIAKDKEARAKLELAAAPKIKTADQDLVVDVGKPLTMVV 6716
Query: 565 KCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACN 624
+ + W K + L S + I + D+ Y V + N
Sbjct: 6717 PYDAYPK-AEAEWFKENEPL---STKTIDTTAEQTSFRILEAKKGDKGRYKIVLQ----N 6768
Query: 625 LSAKLH-FMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIW 683
K F+ +K+ +D PG + + L+V + D ++ W
Sbjct: 6769 KHGKAEGFINLKV------------IDVPGPVRN-----------LEVTETFDGEVSLAW 6805
Query: 684 QKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEK 743
++ +T G + + + D+ CE FTV G +K
Sbjct: 6806 EEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAESCE---------------FTVTGLQK 6850
Query: 744 ED-EGVYTVTVKNPVGEDQVNLTVKVI------DVPDAPAAPKISNVGEDSCTVQWEPPA 796
E ++ V+ +N VG + T + DVP P I++V ++ WEPP
Sbjct: 6851 GGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRFGVSLTWEPPE 6910
Query: 797 YDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSR 856
YDGG I Y++E + K S RW ++LS ++EG Y RV A N IG+ +
Sbjct: 6911 YDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGK 6970
Query: 857 PSPASQPFM----PIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEG 912
PS A+ PF+ PI PS P +L D + ++V LKW PP + G + GY +E C EG
Sbjct: 6971 PSAAT-PFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEG 7029
Query: 913 CSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPR 972
W+ L + V L G + L+RV A N AG P P+T + P
Sbjct: 7030 KDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPT 7089
Query: 973 LQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPL-AGEEVSIRNSPTDTILF 1031
+ L + ++ V P+ +L+P G PRP TW + L G+ V ++ L
Sbjct: 7090 MDLSA-FKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELV 7148
Query: 1032 IRAARRVHSGTYQVTVRIENMED--KATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPP 1089
I + R G Y T+++EN + + V+ +PS P++L+ D +V L W+PP
Sbjct: 7149 ISPSERSDKGIY--TLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHLTWEPP 7206
Query: 1090 QDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSD 1149
D G + L GY V+K + W V++ VP+L+ G Y F+V ++N G
Sbjct: 7207 DDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCG-PG 7265
Query: 1150 RAATTKEPVFIPRPGITYEPP-NYKALDFSEAPSFT--QPLVN--RSVIAGYTAMLCCAV 1204
A EPV + P +PP N K D + F P N S I GY C
Sbjct: 7266 EPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERC--P 7323
Query: 1205 RGSPK 1209
RGS K
Sbjct: 7324 RGSDK 7328
Score = 243 bits (619), Expect = 1e-63
Identities = 204/708 (28%), Positives = 303/708 (42%), Gaps = 81/708 (11%)
Query: 567 EVSDENVRGVWLKNGKELVPDSRIKVSHI--GRVHKLTIDDVTPADEADYSFVPEGFACN 624
+V DE R + E P+++ KV+ + G+ +K + V A E+D + VPE
Sbjct: 10848 KVGDEEWRRA--NHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVK 10905
Query: 625 LSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQ 684
R EPP++ LD I V G+ LRL I G P P V W+
Sbjct: 10906 ---------------DRLEPPELILDANMAREQHIKV--GDTLRLSAIIKGVPFPKVTWK 10948
Query: 685 KAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKE 744
K DAP + R++ T S + A E
Sbjct: 10949 KEDR-----------DAPT--------------------KARIDVTPVGSKLEIRNAAHE 10977
Query: 745 DEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPIL 804
D G+Y++TV+NP G V++ V V+D P P ++S + +DSC + W+ P DGG I
Sbjct: 10978 DGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVIT 11037
Query: 805 GYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMS------RPS 858
Y++ER+ S +W L+ ++ SH A+ + EG Y RV A N G +P
Sbjct: 11038 NYVVERRDVASAQWSPLS-ATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPI 11096
Query: 859 PASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVA 918
A P P GPP + H+ DV T VSL W P+R G + GY VEY EG +W+
Sbjct: 11097 KALDPLHPPGPPKDLHHV---DVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIK 11153
Query: 919 ALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRH 978
+ +V L G FRV+A N+ G G P TT P+ QE L P ++L
Sbjct: 11154 F--KTVTNLECVVTGLQQGKTYRFRVKAENIVGLGLP-DTTIPIECQEKLVPPSVELDVK 11210
Query: 979 LRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPL-AGEEVSIRNSPTDTILFIRAARR 1037
L + + K G V +G P P WT +G + E ++ ++L I+ R
Sbjct: 11211 LIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLR 11270
Query: 1038 VHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQ-DLRVTDAWGLNVALEWKPPQDVGNTE 1096
+G YQ+TV + L V+D P PP + + D ++ + W+PP+D G +
Sbjct: 11271 RDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTISWQPPKDDGGSP 11330
Query: 1097 LWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFS---DRAAT 1153
+ Y V+K D + W V +T +P L G Y FRV ++N +G D T
Sbjct: 11331 VINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPT 11390
Query: 1154 TKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVN-RSVIAGY------TAMLCCAVRG 1206
+ F P P +P + + S+T P + S I GY V
Sbjct: 11391 VAKHKFSP-PSPPGKPVVTDITENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVNK 11449
Query: 1207 SPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCR 1254
+P + + GL G FR+F++ + KP P I CR
Sbjct: 11450 TPIADLKFRVTGLYEGNTYEFRVFAEN---LAGLSKPSPSSDPIKACR 11494
Score = 238 bits (608), Expect = 2e-62
Identities = 190/681 (27%), Positives = 288/681 (42%), Gaps = 96/681 (14%)
Query: 344 DLRGMLKRLKGMRRDEKKSTAFQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEI 403
DLR +++ LK + EKKS F K+ RL V L KW KNG+E+
Sbjct: 6428 DLR-IVEPLKDIETMEKKSVTFWCKVN-----------RLNVTL-------KWTKNGEEV 6468
Query: 404 QMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCSTELFVKEPPVLITRPLEDQ 463
++ + K LTI C D+ Y G +K EL + E P LEDQ
Sbjct: 6469 PFD-NRVSYRVDKYKHMLTIKDCGFPDEGEYIVTAGQDKSVAELLIIEAPTEFVEHLEDQ 6527
Query: 464 LVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAG 523
V F C++S E A VKW ++G E+ +E KY+F+KDG H LII + L+D
Sbjct: 6528 TVTEFDDAVFSCQLSREKANVKWYRNGREI--KEGKKYKFEKDGSIHRLIIKDCRLDDEC 6585
Query: 524 HYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKE 583
YA ++ A L V+E +E+ + D++ VF E++ + V WL+N
Sbjct: 6586 EYACGVEDRKSRARLFVEEIPVEIIRPPQDILEAPGADVVFLAELNKDKVEVQWLRNNMV 6645
Query: 584 LVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQE 643
+V + ++ G++H+L I D+ P D+ +Y F+ AK K++
Sbjct: 6646 VVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFI---------AKDKEARAKLELA---A 6693
Query: 644 PPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPE 703
PKI +VV G L + VP P W K
Sbjct: 6694 APKIK-----TADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKE----------------- 6731
Query: 704 DTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVN 763
++ L +T ++TT +++ F + A+K D+G Y + ++N G+ +
Sbjct: 6732 ----------NEPLSTKT-----IDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGF 6776
Query: 764 LTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNF 823
+ +KVIDVP +++ + ++ WE P DGG I+GY++ER+ K W+ L
Sbjct: 6777 INLKVIDVPGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWV-LAT 6835
Query: 824 DLIQELSHEARRMIE-GVVYEMRVYAVNAIGMSRPSPASQPF---MPIGPPSEPTHLAVE 879
D + + + GV Y RV A N +G P P P P ++ +
Sbjct: 6836 DRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTIT 6895
Query: 880 DVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGAR 939
DV+ VSL W PPE G + Y +E + W A+ E S V D+ G
Sbjct: 6896 DVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQE 6955
Query: 940 LLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQG 999
FRVRA N G G P T V V + ++RP PVNL Q
Sbjct: 6956 YSFRVRAQNRIGVGKPSAATPFVKVADPIERP----------------SPPVNLTSSDQT 6999
Query: 1000 KPRPQVTWTKE----GQPLAG 1016
+ Q+ W G P+ G
Sbjct: 7000 QSSVQLKWEPPLKDGGSPILG 7020
Score = 236 bits (601), Expect = 1e-61
Identities = 159/530 (30%), Positives = 248/530 (46%), Gaps = 48/530 (9%)
Query: 641 RQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPD 700
R EPP+I LD R +V+ A LRL V I G P P V W+KA
Sbjct: 18796 RIEPPEIELDADLR--KVVVLRASATLRLFVTIKGRPEPEVKWEKA-------------- 18839
Query: 701 APEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGED 760
+ +L + R ++E T ++ ++ + D G Y +T++N G
Sbjct: 18840 --------------EGILTD---RAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSGSK 18882
Query: 761 QVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKK--KKSYRW 818
+ V+V+D P AP I V +DS T+ WEPP DGG I YI+E+++ +K+Y
Sbjct: 18883 TAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYAT 18942
Query: 819 MRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAV 878
+ N + + + EG Y RV A N G+ P+ ++P PP P + +
Sbjct: 18943 ITNN---CTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTL 18999
Query: 879 EDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGA 938
DV+ T ++KW PE G + GY VE +G +W Q T +I L G
Sbjct: 19000 VDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVKTLEATI--SGLTAGE 19057
Query: 939 RLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQ 998
+FRV A N G P PV ++I +P ++LP H T K E + + +PF+
Sbjct: 19058 EYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFH---TFNVKAREQLKIDVPFK 19114
Query: 999 GKPRPQVTWTKEGQPLAGE-EVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKAT 1057
G+P+ V W K+GQ L V++ +S T T L I+ A + GTY++ V
Sbjct: 19115 GRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVP 19174
Query: 1058 LVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLE 1117
+ + V+D+P PP +R+ + ++ + W PP+ G ++ Y V+K + + W V +
Sbjct: 19175 ITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQ 19234
Query: 1118 HYRRTHCVVPELIIGNGYYFRVFSQNMVG---FSDRAATTKEPVFIPRPG 1164
RT + L G+ Y FRV ++N G +S+ +A E F P PG
Sbjct: 19235 AVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSP-PG 19283
Score = 234 bits (596), Expect = 5e-61
Identities = 179/608 (29%), Positives = 272/608 (44%), Gaps = 59/608 (9%)
Query: 577 WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKI 636
W G +L R+ V +V KLTI + T D +Y+ + S +K+
Sbjct: 23467 WFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSET-----IKV 23521
Query: 637 DFVPRQEPPK--IHLDCPGRIPDTIVVVAGNKLRLD--VPISGDPAPTVIWQKAITQGNK 692
+ + PP I +D I T + ++ LD P+SG V+ Q+
Sbjct: 23522 IILDKPGPPTGPIKID---EIDATSITISWEPPELDGGAPLSG----YVVEQR------- 23567
Query: 693 APARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVT 752
DA G + V + RS F + +E V+ V
Sbjct: 23568 -------DA------------------HRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVA 23602
Query: 753 VKNPVG-----EDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYI 807
N G + +V I +P P +I +V D T+ W PP DGG + GYI
Sbjct: 23603 ATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYI 23662
Query: 808 LERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM-- 865
+ERK+ ++ RW+R+N + + + + EG+ YE RV A+NA G +PS S+P +
Sbjct: 23663 VERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAM 23722
Query: 866 -PIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLT 924
PI PP +P + V D + T+VSL W PE G + GY +E EW T
Sbjct: 23723 DPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPT 23782
Query: 925 EHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQ 984
+ + LP GA FRV A N GPG P V V E+L+ P +L ++ I
Sbjct: 23783 KIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGIF 23842
Query: 985 KKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQ 1044
+ G + L IP +GKP P WTKEGQ ++ + I S T T L I+ A R SGTY
Sbjct: 23843 VRQGGVIRLTIPIKGKPFPICKWTKEGQDIS-KRAMIATSETHTELVIKEADRGDSGTYD 23901
Query: 1045 VTVRIENMEDKATLVLQVVDKPSPPQ-DLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQ 1103
+ + + + + ++V+ P+ P+ L D +V + W+PP D G ++ GY ++
Sbjct: 23902 LVLENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILE 23961
Query: 1104 KADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRP 1163
+ + W+T+ R T VV L Y+FRV ++N G S + ++EPV P
Sbjct: 23962 RREVPKAAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAENQFGIS-KPLKSEEPVTPKTP 24020
Query: 1164 GITYEPPN 1171
EPP+
Sbjct: 24021 LNPPEPPS 24028
Score = 232 bits (591), Expect = 2e-60
Identities = 155/508 (30%), Positives = 236/508 (46%), Gaps = 43/508 (8%)
Query: 702 PEDTGDSD--EWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVG- 758
P+D G S +V +K+ + V V + +T+ + E V+ + +N G
Sbjct: 9936 PKDDGGSKITNYVIEKRE-ANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGI 9994
Query: 759 ----EDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKK 814
+ + + VP AP P +S+V +S TV WE P YDGG P+ GY LE K
Sbjct: 9995 GEPLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTT 10054
Query: 815 SYRWMRLNFDLIQEL----SHEARRMIEGVVYEMRVYAVNAIGM------SRPSPASQPF 864
S RW R+N D I+ + S++ +IEG Y+ RVYA+NA G+ S P+ A P
Sbjct: 10055 SKRWKRVNRDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPI 10114
Query: 865 MPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLT 924
P GPP V D + ++ L+W PP + G + GY VEY EG EW
Sbjct: 10115 APPGPPFPK----VTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEV 10170
Query: 925 EHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQ 984
T ++V L GA FRVRA N+AG G P T+ + +++ L P LQL +R I
Sbjct: 10171 RGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRDRIV 10230
Query: 985 KKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQ 1044
G + ++ GKP P VTW + L +E +I + + + I+ +R H G Y
Sbjct: 10231 VHAGGVIRIIAYVSGKPPPTVTWNMNERTLP-QEATIETTAISSSMVIKNCQRSHQGVYS 10289
Query: 1045 VTVRIENMEDKATLVLQVVDKPSP-PQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQ 1103
+ + E E K T+++ V+D P P + + L W P+D G + + Y ++
Sbjct: 10290 LLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIE 10349
Query: 1104 KADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGF-----SDRAATTKEPV 1158
K + W V R + V LI G Y+FR+ ++N +G + A +EP+
Sbjct: 10350 KRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPI 10409
Query: 1159 FIP-RP-------------GITYEPPNY 1172
+P RP +T+ PP Y
Sbjct: 10410 TVPERPEDLEVKEVTKNTVTLTWNPPKY 10437
Score = 232 bits (591), Expect = 2e-60
Identities = 161/590 (27%), Positives = 263/590 (44%), Gaps = 48/590 (8%)
Query: 643 EPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAP 702
E P++ LD + IVV AG R+ +P G P P + W +
Sbjct: 17715 EAPELDLD--SELRKGIVVRAGGSARIHIPFKGRPTPEITWSR----------------- 17755
Query: 703 EDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQV 762
+E F K V++E + + +++ ++ D G Y + ++N G
Sbjct: 17756 ------EEGEFTDK--------VQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSA 17801
Query: 763 NLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLN 822
+TVKV+D P P + V +DS + WEPP DGG + Y++++++ + ++
Sbjct: 17802 FVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRESTRKAYANVS 17861
Query: 823 FDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVS 882
+ S + + EG +Y RV A N G+ P PPS P + + DVS
Sbjct: 17862 -SKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEPPSPPGKVTLTDVS 17920
Query: 883 DTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLF 942
T+ SL W PE G + GY VE P+G +W ++ ++ + +V L +G F
Sbjct: 17921 QTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKW--SIVAESKVCNAVVTGLSSGQEYQF 17978
Query: 943 RVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPR 1002
RV+A+N G P PV +++ +P L+LP + T + GE + + IP G+PR
Sbjct: 17979 RVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFN---TYSIQAGEDLKIEIPVIGRPR 18035
Query: 1003 PQVTWTKEGQPL-AGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQ 1061
P ++W K+G+PL V++ + T T+L I+ + G Y VT L +
Sbjct: 18036 PNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVI 18095
Query: 1062 VVDKPSPP-QDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYR 1120
V++KP PP +R + V + W+PP G ++ Y V+K D T W V
Sbjct: 18096 VLEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATVA 18155
Query: 1121 RTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEA 1180
RT + +L G Y FR+F++N G S A + V + P ++ P F +
Sbjct: 18156 RTTIKITKLKTGTEYQFRIFAENRYGKS--APLDSKAVIVQYP---FKEPGPPGTPFVTS 18210
Query: 1181 PSFTQPLV--NRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFR 1228
S Q LV + V G T ++ + K I W K +D +F+
Sbjct: 18211 ISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFK 18260
Score = 231 bits (588), Expect = 4e-60
Identities = 175/602 (29%), Positives = 273/602 (45%), Gaps = 99/602 (16%)
Query: 643 EPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIW------------------- 683
EPP++ +D R D IVV AG L+++ I+G P P + W
Sbjct: 19480 EPPRVMMDVKFR--DVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTD 19537
Query: 684 ----------------QKAITQGNKAPAR-----------PAPDA--------------- 701
Q +T N A R P P A
Sbjct: 19538 NHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSL 19597
Query: 702 ----PEDTG--DSDEWVFDKK-------LLCETEGRVRVETTKDRSIFTVEGAEKEDEGV 748
P++ G D D ++ +K+ +CE G +++ + K + K +E +
Sbjct: 19598 SWGRPQEDGGADIDYYIVEKRETSHLAWTICE--GELQMTSCKVTKLL------KGNEYI 19649
Query: 749 YTVTVKNP--VGEDQVNLTVKVID---VPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPI 803
+ VT N VGE ++ +K +D VP P + +I++V ++S T+ W P DGG I
Sbjct: 19650 FRVTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEI 19709
Query: 804 LGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQP 863
GYI+ER++K S RW+R+N + +L ++ + EG YE RVYA NA G+S PS S
Sbjct: 19710 SGYIIERREKNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPL 19769
Query: 864 FM---PIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAAL 920
P+ PS P+ + D TT+++ W P G + GY+VEY ++W ++
Sbjct: 19770 IRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSI 19829
Query: 921 QGL--TEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRH 978
Q L TE+T + L TGA +FRV++ N G P +++P +E + P +
Sbjct: 19830 QSLRGTEYT---ISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSE 19886
Query: 979 LRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRV 1038
+R+T+ K G + +PF+G+P P V W+K L + + + T L I A R
Sbjct: 19887 MRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLR-TRAYVDTTDSRTSLTIENANRN 19945
Query: 1039 HSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELW 1098
SG Y +T++ TLV++V+D P PP ++ V D + L W P++ G +
Sbjct: 19946 DSGKYTLTIQNVLSAASLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDVPENDGGAPVK 20005
Query: 1099 GYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPV 1158
Y ++K + W +V + R V L G YYFRV +N G A TKE V
Sbjct: 20006 NYHIEKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVG-IPAETKEGV 20064
Query: 1159 FI 1160
I
Sbjct: 20065 KI 20066
Score = 230 bits (587), Expect = 6e-60
Identities = 151/532 (28%), Positives = 240/532 (45%), Gaps = 42/532 (7%)
Query: 641 RQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPD 700
R+E P +D R T++V AG + VP G P P V+W K PD
Sbjct: 19875 REEEPLFDIDSEMR--KTLIVKAGASFTMTVPFRGRPVPNVLWSK-------------PD 19919
Query: 701 APEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGED 760
T R V+TT R+ T+E A + D G YT+T++N +
Sbjct: 19920 TDLRT------------------RAYVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAA 19961
Query: 761 QVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMR 820
+ L VKV+D P P + +V ++S + W+ P DGG P+ Y +E+++ W+
Sbjct: 19962 SLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDVPENDGGAPVKNYHIEKREASKKAWVS 20021
Query: 821 LNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVED 880
+ + LS++ + EG +Y RV N G+ P+ + PS P L V
Sbjct: 20022 VTNNC-NRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGVKITEKPSPPEKLGVTS 20080
Query: 881 VSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARL 940
+S +VSL W PE G + Y VE +G WV + + T +V L +
Sbjct: 20081 ISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQKNWVKC--AVAKSTHHVVSGLRENSEY 20138
Query: 941 LFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGK 1000
FRV A N AG P PV ++E L+ P + + T+ + G + + IP GK
Sbjct: 20139 FFRVFAENQAGLSDPRELLLPVLIKEQLEPPEIDMKNFPSHTVYVRAGSNLKVDIPISGK 20198
Query: 1001 PRPQVTWTKEGQPL-AGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLV 1059
P P+VT +++G PL A + + + + ++ + +G Y++T + KA +
Sbjct: 20199 PLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFIN 20258
Query: 1060 LQVVDKPSPPQ-DLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEH 1118
+ V+D+P PP + ++D +V L+W+PP+ G +++ Y + K + T W V
Sbjct: 20259 IVVLDRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSAT 20318
Query: 1119 YRRTHCVVPELIIGNGYYFRVFSQNMVGFSDR----AATTKEPVFIPRPGIT 1166
RT V +L G Y FR+ ++N G SD T K P P P T
Sbjct: 20319 VARTMMKVMKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPST 20370
Score = 229 bits (585), Expect = 1e-59
Identities = 167/615 (27%), Positives = 275/615 (44%), Gaps = 63/615 (10%)
Query: 565 KCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACN 624
+CE +N W++ +LVP+ KV+ + + +K + V+ ++A S P
Sbjct: 7025 RCEEGKDN----WIRCNMKLVPELTYKVTGLEKGNKY-LYRVSAENKAGVSD-PSEILGP 7078
Query: 625 LSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQ 684
L+A F+E +D D + V+ N + + VP +G P PT W
Sbjct: 7079 LTADDAFVEPTMDL--------------SAFKDGLEVIVPNPITILVPSTGYPRPTATW- 7123
Query: 685 KAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKE 744
F K+L ET RV+++T + + +E+
Sbjct: 7124 ---------------------------CFGDKVL-ETGDRVKMKTLSAYAELVISPSERS 7155
Query: 745 DEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPIL 804
D+G+YT+ ++N V + V VI P AP K ++ +DS + WEPP DGG P+
Sbjct: 7156 DKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLT 7215
Query: 805 GYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPF 864
GY++E+++ W ++ D + +L +++G Y +V A N G P+ +P
Sbjct: 7216 GYVVEKREVSRKTWTKV-MDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPV 7274
Query: 865 ---MPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQ 921
P P P ++ D + ++ L W PP+ G + GY VE CP G +WVA +
Sbjct: 7275 NMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGE 7334
Query: 922 GLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQ 981
+ E T + V L G +RV+A N G P TE + + + P + L L
Sbjct: 7335 PVAE-TKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLA 7393
Query: 982 TIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEE-VSIRNSPTDTILFIRAARRVHS 1040
+ K G + L GKP P++TWTK L ++ ++I N P + + I ++R +
Sbjct: 7394 GLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDT 7453
Query: 1041 GTYQVTVRIENMEDKATLVLQ--VVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELW 1098
GTY + N+ +AT V++ V+DKP PP +TD + L W PP+D G +++
Sbjct: 7454 GTY--IIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKIT 7511
Query: 1099 GYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSD----RAATT 1154
Y V++ + W + + T+ +LI Y FRV ++NM G + T
Sbjct: 7512 NYVVERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITA 7571
Query: 1155 KEPVFIPRPGITYEP 1169
K P P EP
Sbjct: 7572 KYQFDPPGPPTRLEP 7586
Score = 225 bits (574), Expect = 2e-58
Identities = 166/609 (27%), Positives = 271/609 (44%), Gaps = 60/609 (9%)
Query: 643 EPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAP 702
E P I LD R I + AG LRL VPI G P P V W K
Sbjct: 16633 EAPDIDLDLELR--KIINIRAGGSLRLFVPIKGRPTPEVKWGKV---------------- 16674
Query: 703 EDTGDSDEWVFDKKLLCETEGRVR----VETTKDRSIFTVEGAEKEDEGVYTVTVKNPVG 758
+G +R ++ T + ++ + D G YT+T++N G
Sbjct: 16675 -------------------DGEIRDAAIIDVTSSFTSLVLDNVNRYDSGKYTLTLENSSG 16715
Query: 759 EDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKK--KKSY 816
+TV+V+D P P K++ + +DS ++ WEPP DGG I YI+E+++ +KSY
Sbjct: 16716 TKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEKREATRKSY 16775
Query: 817 RWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHL 876
+ N + S + ++ EG Y RV A N G+ P+ + P P P +
Sbjct: 16776 AAVVTN---CHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPPGKI 16832
Query: 877 AVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPT 936
V+DV+ +VSL W PE G + Y VE + +W + + ++ +L
Sbjct: 16833 TVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECAR--VKSLQAVITNLTQ 16890
Query: 937 GARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIP 996
G LFRV A N G P + P+ ++++ P ++ P ++Q VG+ + + +P
Sbjct: 16891 GEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVK-PAFSSYSVQ--VGQDLKIEVP 16947
Query: 997 FQGKPRPQVTWTKEGQPL-AGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDK 1055
G+P+P +TWTK+G PL +++ +S T L I+ + G Y +TV +
Sbjct: 16948 ISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKT 17007
Query: 1056 ATLVLQVVDKPSPPQ-DLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFT 1114
A++ + +DKP PP+ ++ D ++ L W PP G ++ Y VQK D T W
Sbjct: 17008 ASIEIVTLDKPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDV 17067
Query: 1115 VLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKA 1174
V RT V +L G Y FR+F++N G S A +P+ P Y+ P
Sbjct: 17068 VSATVARTTLKVTKLKTGTEYQFRIFAENRYGQS--FALESDPIVAQYP---YKEPGPPG 17122
Query: 1175 LDFSEAPSFTQPLV--NRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSK 1232
F+ A S ++ + V G + ++ + + I W K + D +F+ +
Sbjct: 17123 TPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNL 17182
Query: 1233 QGVLTLEIR 1241
+ + E R
Sbjct: 17183 EEGIEYEFR 17191
Score = 224 bits (571), Expect = 4e-58
Identities = 156/532 (29%), Positives = 231/532 (43%), Gaps = 44/532 (8%)
Query: 622 ACNLSAKLHFME--VKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAP 679
A N+ + E +I+ V R E P + L + T+ + AG LRL V +SG P P
Sbjct: 23114 AVNVKGMSEYSESIAEIEPVERIEIPDLEL--ADDLKKTVTIRAGASLRLMVSVSGRPPP 23171
Query: 680 TVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVE 739
+ W K QG + R ++TT+ S+ V+
Sbjct: 23172 VITWSK---QG----------------------------IDLASRAIIDTTESYSLLIVD 23200
Query: 740 GAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDG 799
+ D G YT+ +N G+ + VKV D P + K+ V DS T+ WE P DG
Sbjct: 23201 KVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDG 23260
Query: 800 GQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSP 859
G P+ YI+E K++ + R + + + ++EG +Y RV N G+ P
Sbjct: 23261 GAPVNNYIVE-KREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCE 23319
Query: 860 ASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEW--- 916
S + P P L V DV+ +TV+L W P G L GY +E C G W
Sbjct: 23320 TSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKV 23379
Query: 917 VAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLP 976
V + EHT V L G + LFR+RA N G P T VTVQ++ P + L
Sbjct: 23380 VTLKPTVLEHT---VTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLS 23436
Query: 977 RHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPL-AGEEVSIRNSPTDTILFIRAA 1035
++TI G PV L+IP G+P P +W G L E V++ L IR
Sbjct: 23437 TMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRET 23496
Query: 1036 RRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQ-DLRVTDAWGLNVALEWKPPQDVGN 1094
+G Y + ++ T+ + ++DKP PP +++ + ++ + W+PP+ G
Sbjct: 23497 TIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEPPELDGG 23556
Query: 1095 TELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVG 1146
L GY V++ D W V E R+ L GN Y FRV + N G
Sbjct: 23557 APLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFG 23608
Score = 220 bits (561), Expect = 6e-57
Identities = 171/617 (27%), Positives = 257/617 (41%), Gaps = 63/617 (10%)
Query: 575 GVWLKNGKELVPDSRIKVSHI--GRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFM 632
G W K E +R V+ + G +K + + A + D +C ++
Sbjct: 21993 GDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGD--------SCEVTGT---- 22040
Query: 633 EVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNK 692
I V R P++ +D T VV AG +RL + G P PT +W K
Sbjct: 22041 ---IKAVDRLTAPELDIDA--NFKQTHVVRAGASIRLFIAYQGRPTPTAVWSK------- 22088
Query: 693 APARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVT 752
PD+ R + TT S TVE + D G YT+T
Sbjct: 22089 ------PDS------------------NLSLRADIHTTDSFSTLTVENCNRNDAGKYTLT 22124
Query: 753 VKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKK 812
V+N G + TVKV+D P P +V S T+ W+ P DGG I Y++E+++
Sbjct: 22125 VENNSGSKSITFTVKVLDTPGPPGPITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKRE 22184
Query: 813 KKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSE 872
W ++ +++ + + EGV Y RV AVN G+ P +P + P+
Sbjct: 22185 ASRRSWQVISEKCTRQI-FKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAP 22243
Query: 873 PTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVK 932
P L V D S ++ L W P+ G + GY +E +G WV A G T+ + V+
Sbjct: 22244 PRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEA--GHTKQLTFTVE 22301
Query: 933 DLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVN 992
L FRV+A N AG P V ++E P L Q I K G P
Sbjct: 22302 RLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFT 22361
Query: 993 LLIPFQGKPRPQVTWTKEGQPL-AGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIEN 1051
+ +P G+P P+VTW E L + VSI + T L ++ + R SG Y +T+
Sbjct: 22362 IDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTA 22421
Query: 1052 MEDKATLVLQVVDKPSP-PQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTM 1110
++ + V+ +P P + V+ + L W P+D G TE+ Y V+K + T
Sbjct: 22422 GVKTFSVTVVVIGRPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTT 22481
Query: 1111 EWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFS---DRAATTKEPVFIP-----R 1162
W V +RT V L Y FRV S+N G S + A E F+P R
Sbjct: 22482 AWQLVNSSVKRTQIKVTHLTKYMEYSFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPTR 22541
Query: 1163 PGITYEPPNYKALDFSE 1179
P + + N ++ + E
Sbjct: 22542 PEVYHVSANAMSIRWEE 22558
Score = 219 bits (559), Expect = 1e-56
Identities = 172/604 (28%), Positives = 278/604 (46%), Gaps = 64/604 (10%)
Query: 577 WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKI 636
W+K +EL +R+++ L++ D D +Y + A S ++ VK+
Sbjct: 16272 WIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVN---VKV 16328
Query: 637 DFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPAR 696
LD PG P+ VV++G ++ + T+ W+ + G
Sbjct: 16329 ------------LDRPGP-PEGPVVISG--------VTAEKC-TLAWKPPLQDGGS---- 16362
Query: 697 PAPDAPEDTGDSDEWVFDKK---LLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTV 753
D ++ +++ L T V+T + +EG +E + +
Sbjct: 16363 ----------DIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEG----NEYTFRIMA 16408
Query: 754 KNPVG-----EDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYIL 808
N G E + + VPDAP AP+++ V +DS V WE PA DGG ILGY+L
Sbjct: 16409 VNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPASDGGSEILGYVL 16468
Query: 809 ERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPAS---QPFM 865
E++ K+ RW R + LI EL +IE YE RV A NA G+S PSP S +
Sbjct: 16469 EKRDKEGIRWTRCHKRLIGELRLRVTGLIENHDYEFRVSAENAAGLSEPSPPSAYQKACD 16528
Query: 866 PIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAAL--QGL 923
PI P P + V D++ ++V L W P G + GY VE C EW G+
Sbjct: 16529 PIYKPGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGI 16588
Query: 924 TEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTI 983
+ T+I V+ L FR+ A N AG G P+ V+E L+ P + L LR+ I
Sbjct: 16589 NK-TNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDLELRKII 16647
Query: 984 QKKVGEPVNLLIPFQGKPRPQVTWTK-EGQPLAGEEVSIRNSPTDTILFIRAARRVHSGT 1042
+ G + L +P +G+P P+V W K +G+ + + +S T +L R SG
Sbjct: 16648 NIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLVL--DNVNRYDSGK 16705
Query: 1043 YQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTV 1102
Y +T+ + A + ++V+D PSPP +L+VT+ +V++ W+PP G +++ Y V
Sbjct: 16706 YTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIV 16765
Query: 1103 QKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPV---F 1159
+K + + V+ + + + +L G YYFRV ++N G A T +P+
Sbjct: 16766 EKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIG-LPAQTADPIKVAE 16824
Query: 1160 IPRP 1163
+P+P
Sbjct: 16825 VPQP 16828
Score = 219 bits (557), Expect = 2e-56
Identities = 152/493 (30%), Positives = 234/493 (47%), Gaps = 38/493 (7%)
Query: 700 DAPEDTGDSD--EWVFDKKLLCETEGRVRVETTKDRSIFT----VEGAEKEDEGVYTVTV 753
D PED G + ++ +K CET+ V +T ++ T V + +E ++ V
Sbjct: 12013 DPPEDDGGCEIQNYILEK---CETKRMVW--STYSATVLTPGTTVTRLIEGNEYIFRVRA 12067
Query: 754 KNPVGEDQVNLTVKVI-----DVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYIL 808
+N +G + VI D P P P+++ V ++ TV W PP YDGG+ I GY L
Sbjct: 12068 ENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFL 12127
Query: 809 ERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM--- 865
E+K+K S RW+ +N I E + + ++ Y+ RV A N IG+ PS S+P +
Sbjct: 12128 EKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKD 12187
Query: 866 PIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCP--------EGCSEWV 917
PI PP PT+ V D + +++L W P G + GY VE P EG
Sbjct: 12188 PIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCN 12247
Query: 918 AALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPR 977
AA Q + + V L FRV A N G G P E + +EIL+ P + L
Sbjct: 12248 AAAQLVRK--EFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEPPEIDLDA 12305
Query: 978 HLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARR 1037
+R+ + + G P+ L +G+P P+VTW K G + + T L I + R
Sbjct: 12306 SMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDTMAFLVIPNSTR 12365
Query: 1038 VHSGTYQVTVRIENMEDKATLV-LQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTE 1096
SG Y +T+ + +KA V ++V+D P P DL+V+D + + W PP++ G ++
Sbjct: 12366 DDSGKYSLTL-VNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQ 12424
Query: 1097 LWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKE 1156
+ Y V+K + W TV ++T V L+ GN YYFRV + N G
Sbjct: 12425 VTHYIVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYG-------PGV 12477
Query: 1157 PVFIPRPGITYEP 1169
P +P+P + +P
Sbjct: 12478 PTDVPKPVLASDP 12490
Score = 218 bits (554), Expect = 4e-56
Identities = 174/627 (27%), Positives = 269/627 (42%), Gaps = 72/627 (11%)
Query: 573 VRGV------WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLS 626
+RGV W +G E+ D V LTI + D +Y A + +
Sbjct: 11229 IRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKT 11288
Query: 627 AKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKA 686
+H LD PG I + LDV T+ WQ
Sbjct: 11289 VAVHLTV---------------LDVPGPPTGPINI-------LDVT---PEHMTISWQP- 11322
Query: 687 ITQGNKAPARPAPDAPEDTGDSD--EWVFDKK-LLCETEGRVRVETTKDRSIFTVEGAEK 743
P+D G S ++ +K+ +T G V ++K + + +K
Sbjct: 11323 ---------------PKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTK--LKIPHLQK 11365
Query: 744 EDEGVYTVTVKNPVG-----EDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYD 798
E V+ V +N +G + + P P P ++++ E++ TV W P D
Sbjct: 11366 GCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWTLPKSD 11425
Query: 799 GGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPS 858
GG PI GY +ER++ +W+R+N I +L + EG YE RV+A N G+S+PS
Sbjct: 11426 GGSPITGYYMERREVTG-KWVRVNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPS 11484
Query: 859 PASQPFM---PIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSE 915
P+S P PI PP P + ++D S T L W P G + GY VE G ++
Sbjct: 11485 PSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQ 11544
Query: 916 WVAALQG-LTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQ 974
W + L + V L G FR++A N+ G G P E V ++IL P ++
Sbjct: 11545 WNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVE 11604
Query: 975 LPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEE-VSIRNSPTDTILFIR 1033
L R I +VG+ + +L +G+P P +TWTKEG+ L E+ V + L I+
Sbjct: 11605 LDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIK 11664
Query: 1034 AARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVG 1093
A R G Y ++ + + + + ++ V+D+P P Q+L+VT+ N + W+ P D G
Sbjct: 11665 EAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKENCTISWENPLDNG 11724
Query: 1094 NTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAAT 1153
+E+ + V+ W V + + L+ N YYFRV ++N VG
Sbjct: 11725 GSEITNFIVEYRKPNQKGWSIVASDVTK-RLIKANLLANNEYYFRVCAENKVGVGP-TIE 11782
Query: 1154 TKEPVF----IPRPGITYEPPNYKALD 1176
TK P+ I RPG EP N D
Sbjct: 11783 TKTPILAINPIDRPG---EPENLHIAD 11806
Score = 218 bits (554), Expect = 4e-56
Identities = 153/548 (27%), Positives = 243/548 (44%), Gaps = 49/548 (8%)
Query: 633 EVKIDFVPRQ--EPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQG 690
E+K P++ EPP+I LD R ++V AG +RL + G PAP V W+K G
Sbjct: 12285 ELKEAIKPKEILEPPEIDLDASMR--KLVIVRAGCPIRLFAIVRGRPAPKVTWRKV---G 12339
Query: 691 NKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYT 750
R +V+ + + + ++D G Y+
Sbjct: 12340 IDNVVRKG---------------------------QVDLVDTMAFLVIPNSTRDDSGKYS 12372
Query: 751 VTVKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILER 810
+T+ NP GE V + V+V+D P + K+S+V + SC V W PP DGG + YI+E+
Sbjct: 12373 LTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEK 12432
Query: 811 KKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PI 867
++ W + + +++ S ++ G Y RV AVN G P+ +P + P+
Sbjct: 12433 READRKTWSTVTPE-VKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPL 12491
Query: 868 GPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEG--CSEWVAALQGLTE 925
P P L V +++ + +L W PP R G +DGY Y E W + +
Sbjct: 12492 SEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTE--YSVVK 12549
Query: 926 HTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQK 985
S++V L G + FRV A N G P +E L P++ +P + I
Sbjct: 12550 DLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMP----EQITI 12605
Query: 986 KVGEPVNLLIPFQGKPRPQVTWTK-EGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQ 1044
K G+ + + GKP P W K E + + +++ + + +IL I+ R SG Y
Sbjct: 12606 KAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYS 12665
Query: 1045 VTVRIENMEDKATLVLQVVDKPSPPQD-LRVTDAWGLNVALEWKPPQDVGNTELWGYTVQ 1103
+T + D + + V+D P PPQ ++D +L W P + G + + Y V+
Sbjct: 12666 LTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSLSWHIPLEDGGSNITNYIVE 12725
Query: 1104 KADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRP 1163
K D +W T L +T C V +LI G Y FRV ++N G S+ + K P
Sbjct: 12726 KCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPF- 12784
Query: 1164 GITYEPPN 1171
G+ EP N
Sbjct: 12785 GVPSEPKN 12792
Score = 217 bits (552), Expect = 7e-56
Identities = 151/520 (29%), Positives = 234/520 (45%), Gaps = 42/520 (8%)
Query: 636 IDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPA 695
I+ R P + LD R D IVV AG +R+ +SG P PTV W
Sbjct: 10208 IEMKDRLVSPDLQLDASVR--DRIVVHAGGVIRIIAYVSGKPPPTVTWNMN--------E 10257
Query: 696 RPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKN 755
R P +ETT S ++ ++ +GVY++ KN
Sbjct: 10258 RTLPQ-----------------------EATIETTAISSSMVIKNCQRSHQGVYSLLAKN 10294
Query: 756 PVGEDQVNLTVKVIDVPDAPAAPKIS-NVGEDSCTVQWEPPAYDGGQPILGYILERKKKK 814
GE + + V V+DVP P ++ N+ +SC + W P DGG PI Y++E+++
Sbjct: 10295 EAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESD 10354
Query: 815 SYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PIGPPS 871
W + + + ++ + + +I+G Y R+ A N+IGM S+ + PI P
Sbjct: 10355 RRAWTPVTYTVTRQ-NATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPE 10413
Query: 872 EPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILV 931
P L V++V+ TV+L W PP+ G + Y +E G ++ V
Sbjct: 10414 RPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTV 10473
Query: 932 KDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPV 991
K L G +RV A N+ G G P T+P+T ++ L P L L + TI +VGE
Sbjct: 10474 KGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHLDFRDKLTI--RVGEAF 10531
Query: 992 NLLIPFQGKPRPQVTWTK-EGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIE 1050
L + GKP+P+V+W K E L + I+ +P L A+R SG Y V V
Sbjct: 10532 ALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENS 10591
Query: 1051 NMEDKATLVLQVVDKPSPPQD-LRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKT 1109
K + VVD+P PP + + + + WKPP D G +++ Y ++K +
Sbjct: 10592 TGSRKGFCQVNVVDRPGPPVGPVSFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGK 10651
Query: 1110 MEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSD 1149
W V +T C V +L+ G Y FR+ ++N+ G SD
Sbjct: 10652 DVWMPVTSASAKTTCKVSKLLEGKDYIFRIHAENLYGISD 10691
Score = 214 bits (546), Expect = 3e-55
Identities = 169/608 (27%), Positives = 283/608 (46%), Gaps = 58/608 (9%)
Query: 643 EPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAP 702
E P+I LD R +++ AG +++ +P G P PTV W+K
Sbjct: 20962 EAPEIDLDVALRT--SVIAKAGEDVQVLIPFKGRPPPTVTWRK----------------- 21002
Query: 703 EDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQV 762
D+K L ++ R +E T S+ T+ + D G Y +T++N VGE +
Sbjct: 21003 -----------DEKNL-GSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKS 21050
Query: 763 N-LTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRL 821
+ ++VKV+D P A ++ +V + T+ W+PP DGG PI+ Y++E++ W +
Sbjct: 21051 STVSVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVV 21110
Query: 822 NFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDV 881
+ S + + E + RV A N IG+ P ++P P+ L+++D
Sbjct: 21111 SHKC-SSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDS 21169
Query: 882 SDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLL 941
+ T+V L W P+ G + Y VE +G W A G+++ I V L + L
Sbjct: 21170 TKTSVILSWTKPDFDGGSVITEYVVERKGKGEQTWSHA--GISKTCEIEVSQLKEQSVLE 21227
Query: 942 FRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKP 1001
FRV A N G PVT P+TV+E++ P + L + ++G V+L +P++GKP
Sbjct: 21228 FRVFAKNEKGLSDPVTIG-PITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKP 21286
Query: 1002 RPQVTWTKEGQPLAGEEVSIRNSPTDT--ILFIRAARRVHSGTYQVTVRIENMEDKATLV 1059
+P ++W K+G PL E +R S T+ L I+ A++ H G Y TV ++N + +
Sbjct: 21287 KPSISWLKDGLPLKESEF-VRFSKTENKITLSIKNAKKEHGGKY--TVILDNAVCRIAVP 21343
Query: 1060 LQVV--DKPSPPQ-DLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVL 1116
+ V+ PS P+ +R + +V L W P+D G E+ Y+++K + W V
Sbjct: 21344 ITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTNWKMVC 21403
Query: 1117 EHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATT----KEPVFIPRPGITYEPPNY 1172
RT VP L+ Y FRV ++N G S ++ K IP P +P Y
Sbjct: 21404 SSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGP--PGKPVIY 21461
Query: 1173 KALDFSEAPSFTQPLVN-RSVIAGY-------TAMLCCAVRGSPKPKISWFKNGLDLGED 1224
+ ++ P+ + S + G+ ++L V SP + GL G D
Sbjct: 21462 NVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLD 21521
Query: 1225 ARFRMFSK 1232
+FR++++
Sbjct: 21522 YQFRVYAE 21529
Score = 213 bits (543), Expect = 7e-55
Identities = 137/438 (31%), Positives = 210/438 (47%), Gaps = 12/438 (2%)
Query: 732 DRSIFTVEGAEKEDEGVYTVTVKNPVG-----EDQVNLTVKVIDVPDAPAAPKISNVGED 786
+ I T K +E ++ V N G E + P P P+++ + ++
Sbjct: 20716 EECIITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKN 20775
Query: 787 SCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRV 846
S TV W P DGG I GY LE++ KKS W ++ + I++ + + E Y+ RV
Sbjct: 20776 SMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRV 20835
Query: 847 YAVNAIGM---SRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDG 903
AVNA G S PS + PI PP P + + D + ++++L W P G + G
Sbjct: 20836 CAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTG 20895
Query: 904 YSVEYCPEGCSEWVA-ALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPV 962
Y VE EW + +G T +V +L G FRV A N AG G P+ EPV
Sbjct: 20896 YVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPV 20955
Query: 963 TVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGE-EVSI 1021
++IL+ P + L LR ++ K GE V +LIPF+G+P P VTW K+ + L + SI
Sbjct: 20956 QAKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSI 21015
Query: 1022 RNSPTDTILFIRAARRVHSGTYQVTVRIENMEDK-ATLVLQVVDKPSPPQDLRVTDAWGL 1080
N+ + ++L I R +G Y +T+ E K +T+ ++V+D P+ Q L+V
Sbjct: 21016 ENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRG 21075
Query: 1081 NVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVF 1140
V L W PP G + + Y ++K D W V T + +L ++FRV
Sbjct: 21076 TVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVL 21135
Query: 1141 SQNMVGFSDRAATTKEPV 1158
++N +G + TT EPV
Sbjct: 21136 AENEIGIGEPCETT-EPV 21152
Score = 212 bits (540), Expect = 2e-54
Identities = 170/605 (28%), Positives = 264/605 (43%), Gaps = 59/605 (9%)
Query: 641 RQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPD 700
R PP+I LD R + + A LRL VPI G PAP V W +
Sbjct: 15549 RMLPPEIELDADLR--KVVTIRACCTLRLFVPIKGRPAPEVKWAR--------------- 15591
Query: 701 APEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGED 760
D G+S + + +E+T ++ V + D G Y +TV+N G
Sbjct: 15592 ---DHGESLD-------------KASIESTSSYTLLIVGNVNRFDSGKYILTVENSSGSK 15635
Query: 761 QVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKK--KKSYRW 818
+ V+V+D P P K+ V + S T+ W+PP DGG I YI+E+++ +K+Y
Sbjct: 15636 SAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVEKRESTRKAYST 15695
Query: 819 MRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAV 878
+ N + S + ++ EG Y RV A N G+ P+ ++ P P + +
Sbjct: 15696 VATN---CHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKASERPLPPGKITL 15752
Query: 879 EDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGA 938
DV+ +VSL W PE G + GY VE +G +W A + T + L G
Sbjct: 15753 MDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKW--ATCATVKVTEATITGLIQGE 15810
Query: 939 RLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQ 998
FRV A N G P + PV ++++ P +L L T GE + + +PF
Sbjct: 15811 EYSFRVSAQNEKGISDPRQLSVPVIAKDLVIPPAFKL---LFNTFTVLAGEDLKVDVPFI 15867
Query: 999 GKPRPQVTWTKEGQPL-AGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKAT 1057
G+P P VTW K+ PL V+ ++ +++L I+ A R G Y V + E T
Sbjct: 15868 GRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIET 15927
Query: 1058 LVLQVVDKPSPPQ-DLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVL 1116
L + V+DKP PP +++ + ++ L W PP+ G + + Y V+K D T W V
Sbjct: 15928 LNVIVLDKPGPPTGPVKMDEVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTWQIVS 15987
Query: 1117 EHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALD 1176
RT L G Y FR+ ++N G S EP P PP +
Sbjct: 15988 ATVARTTIKACRLKTGCEYQFRIAAENRYGKS--TYLNSEPTVAQYPFKVPGPPGTPVVT 16045
Query: 1177 FSEAPS----FTQPLVN-RSVIAGY-------TAMLCCAVRGSPKPKISWFKNGLDLGED 1224
S S + +P+ + S + GY ++L + +P P+ + GL+ G +
Sbjct: 16046 LSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGVE 16105
Query: 1225 ARFRM 1229
FR+
Sbjct: 16106 YEFRV 16110
Score = 211 bits (537), Expect = 4e-54
Identities = 158/561 (28%), Positives = 244/561 (43%), Gaps = 48/561 (8%)
Query: 644 PPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPE 703
PP+ LD R T+++ AG +RL VP+ G P P + W K P + +
Sbjct: 13385 PPEGELDADLR--KTLILRAGVTMRLYVPVKGRPPPKITWSK-----------PNVNLRD 13431
Query: 704 DTG-DSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQV 762
G D FD L C E K D G Y +T++N G+ +
Sbjct: 13432 RIGLDIKSTDFDTFLRC-------------------ENVNKYDAGKYILTLENSCGKKEY 13472
Query: 763 NLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLN 822
+ VKV+D P P + + +DS V WEPP DGG PI+ Y+++++ + W +
Sbjct: 13473 TIVVKVLDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVT 13532
Query: 823 FDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVS 882
+ + S + EG Y RV+A N G+ P P L V VS
Sbjct: 13533 TE-CSKTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVVDLKVRSVS 13591
Query: 883 DTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLF 942
++ S+ W+ P G + GY V++ E ++W ++ L+ S KDL G F
Sbjct: 13592 KSSCSIGWKKPHSDGGSRIIGYVVDFLTEE-NKWQRVMKSLSLQYS--AKDLTEGKEYTF 13648
Query: 943 RVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPR 1002
RV A N G G P T V ++ + P L L K L IP +GKP
Sbjct: 13649 RVSAENENGEGTPSEIT--VVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPA 13706
Query: 1003 PQVTWTKEGQPLAGE-EVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQ 1061
P V+W K PLA + VS+ +S +T L + ++ +G Y +T++ + T+ ++
Sbjct: 13707 PSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIK 13766
Query: 1062 VVDKPS-PPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYR 1120
VV KP P ++ + + L+W PP+D G +E+ Y ++K D +W T +
Sbjct: 13767 VVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCASAVQ 13826
Query: 1121 RTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRP-GITYEPPNYKALDF-- 1177
+T V L G Y FRV ++N G + EP+ P + PP +D
Sbjct: 13827 KTTFRVTRLHEGMEYTFRVSAENKYGVGE--GLKSEPIVARHPFDVPDAPPPPNIVDVRH 13884
Query: 1178 -SEAPSFTQP-LVNRSVIAGY 1196
S + ++T P S I GY
Sbjct: 13885 DSVSLTWTDPKKTGGSPITGY 13905
Score = 211 bits (537), Expect = 4e-54
Identities = 149/517 (28%), Positives = 234/517 (45%), Gaps = 47/517 (9%)
Query: 636 IDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPA 695
++ V R+ P LD R T+VV AG +R+ VPI G PAP V W K
Sbjct: 14460 VEIVEREMAPDFELDAELR--RTLVVRAGLSIRIFVPIKGRPAPEVTWTK---------- 14507
Query: 696 RPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKN 755
D+ + R +E T+ ++ + + D G + +T++N
Sbjct: 14508 -----------DN----------INLKNRANIENTESFTLLIIPECNRYDTGKFVMTIEN 14546
Query: 756 PVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKK--K 813
P G+ + V+V+D P + +++ +DS T+ W+ P DGG I YI+E+++ +
Sbjct: 14547 PAGKKSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATR 14606
Query: 814 KSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEP 873
KSY + +++ + EG Y RV A N G+ P+ ++P PS P
Sbjct: 14607 KSYSTATTK---CHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPP 14663
Query: 874 THLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEW--VAALQGLTEHTSILV 931
L + D++ +TVSL W P+ G + GY +E +G +W + ++GL +V
Sbjct: 14664 DSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQWTHITTVKGL----ECVV 14719
Query: 932 KDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPV 991
++L G F+V A N AG AP + PV V+E P L L ++ + K G+ +
Sbjct: 14720 RNLTEGEEYTFQVMAVNSAGRSAP-RESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNI 14778
Query: 992 NLLIPFQGKPRPQVTWTKEGQPL-AGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIE 1050
+ IP G+P+P VTW K Q L + V+ + T TIL I R SG Y +T R
Sbjct: 14779 KVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNI 14838
Query: 1051 NMEDKATLVLQVVDKPSPPQ-DLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKT 1109
E + +QV D P PP ++ + V W PP++ G + Y V+ +
Sbjct: 14839 VGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDS 14898
Query: 1110 MEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVG 1146
W + RT L G Y FRV +QN G
Sbjct: 14899 TTWVELATTVIRTTYKATRLTTGLEYQFRVKAQNRYG 14935
Score = 209 bits (531), Expect = 2e-53
Identities = 164/608 (26%), Positives = 257/608 (42%), Gaps = 65/608 (10%)
Query: 577 WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKI 636
W K E+V S + V L I DVT D YS E S+ ++K+
Sbjct: 12627 WKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAEN-----SSGTDTQKIKV 12681
Query: 637 DFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKA-ITQGNKAPA 695
+ PP+ D I D + + G I +K +++G
Sbjct: 12682 VVMDAPGPPQPPFD----ISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRG----- 12732
Query: 696 RPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKN 755
+WV + +T RV + G E ++ V +N
Sbjct: 12733 --------------DWVTALASVTKTSCRVGK---------LIPGQEY----IFRVRAEN 12765
Query: 756 PVGEDQVNLTVKVI-----DVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILER 810
G + + K++ VP P +++ V +D V W+ P DGG PI+GY++ER
Sbjct: 12766 RFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIER 12825
Query: 811 KKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQ---PFMPI 867
K++ S W++ N L++ + ++EG+ Y R+YA+N G S PS ++ MP+
Sbjct: 12826 KERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPV 12885
Query: 868 GPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTE-- 925
PP +P V DV+ +TVSL W P+ G + GY VE C +WV +
Sbjct: 12886 DPPGKP---EVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIP 12942
Query: 926 HTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQK 985
L A+ FR A P ++PVT+ PR+ L ++ +
Sbjct: 12943 QEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVAMKSLLTV 13002
Query: 986 KVGEPVNLLIPFQGKPRPQVTWTKEG---QPLAGEEVSIRNSPTDTILFIRAARRVHSGT 1042
K G V L GKP P V+W K+G +P G +++++ + LF + R SG
Sbjct: 13003 KAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELF--SVNRKDSGD 13060
Query: 1043 YQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTV 1102
Y +T + AT+ L+V+DKP PP +++ + L W+PP + G +E+ Y V
Sbjct: 13061 YTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIV 13120
Query: 1103 QKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPR 1162
K + W V T C V +LI G+ Y FR+ ++N G D T EP
Sbjct: 13121 DKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFT--EPAIAKN 13178
Query: 1163 PGITYEPP 1170
P Y+PP
Sbjct: 13179 P---YDPP 13183
Score = 207 bits (526), Expect = 7e-53
Identities = 139/404 (34%), Positives = 194/404 (48%), Gaps = 13/404 (3%)
Query: 771 VPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELS 830
VPDAP P ++ V +DS V W P +DGG+PI YILE+++ S RW R+ D I +
Sbjct: 10706 VPDAPDQPIVTEVTKDSALVTWNKP-HDGGKPITNYILEKRETMSKRWARVTKDPIHPYT 10764
Query: 831 H-EARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PIGPPSEPTHLAVEDVSDTTV 886
++EG YE RV A N IG+ PSP S+P PI PS P + D + +V
Sbjct: 10765 KFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSV 10824
Query: 887 SLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAA--LQGLTEHTSILVKDLPTGARLLFRV 944
L W+PP G + GY VEY G EW A T V L G FRV
Sbjct: 10825 DLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRV 10884
Query: 945 RAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQ 1004
A N AG P EPV V++ L+ P L L ++ + KVG+ + L +G P P+
Sbjct: 10885 LAVNAAGESDPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPK 10944
Query: 1005 VTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVD 1064
VTW KE + A + I +P + L IR A G Y +TV ++ + V+D
Sbjct: 10945 VTWKKEDRD-APTKARIDVTPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLD 11003
Query: 1065 KPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHC 1124
KP PP+DL V++ + L WK P D G + + Y V++ D + +W + ++
Sbjct: 11004 KPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSH 11063
Query: 1125 VVPELIIGNGYYFRVFSQNMVGFSDRAATTK-----EPVFIPRP 1163
L GN Y FRV ++N G T K +P+ P P
Sbjct: 11064 FAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGP 11107
Score = 206 bits (524), Expect = 1e-52
Identities = 169/608 (27%), Positives = 260/608 (42%), Gaps = 74/608 (12%)
Query: 577 WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFV---PEGFACNLSAKLHFME 633
W K+GKEL +++++ L D T D Y+ P GFA H
Sbjct: 15190 WSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGGFA------KHIFN 15243
Query: 634 VKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKA 693
VK+ LD PG P G A T + + K
Sbjct: 15244 VKV------------LDRPG------------------PPEGPLAVTEVTSE------KC 15267
Query: 694 PARPAPDAPEDTGDSDEWVFDKK---LLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYT 750
P + D ++ K+ L T V+ TK + ++G +E ++
Sbjct: 15268 VLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKG----NEYIFR 15323
Query: 751 VTVKNPVG-----EDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILG 805
V N G E + L V PD P P+++ + +DS V W P DGG I+
Sbjct: 15324 VMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIIN 15383
Query: 806 YILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM 865
YI+ER+ K RW++ N + +L ++ + EG YE R+ A NA G+S PSP S PF
Sbjct: 15384 YIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTS-PFY 15442
Query: 866 PI-------GPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEW-- 916
GPP P V D S +++S+ W P G + GY VE EW
Sbjct: 15443 KACDTVFKPGPPGNP---RVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQI 15499
Query: 917 VAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLP 976
V GL + TS + L R+ A N G G P ++ + P ++L
Sbjct: 15500 VTPPAGL-KATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEIELD 15558
Query: 977 RHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKE-GQPLAGEEVSIRNSPTDTILFIRAA 1035
LR+ + + + L +P +G+P P+V W ++ G+ L ++ SI ++ + T+L +
Sbjct: 15559 ADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDHGESL--DKASIESTSSYTLLIVGNV 15616
Query: 1036 RRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNT 1095
R SG Y +TV + A + ++V+D P PPQDL+V + +V L W PP G +
Sbjct: 15617 NRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGS 15676
Query: 1096 ELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTK 1155
++ Y V+K + + TV + +T V +L G YYFRV ++N G A T +
Sbjct: 15677 KIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAE 15736
Query: 1156 EPVFIPRP 1163
RP
Sbjct: 15737 SVKASERP 15744
Score = 205 bits (522), Expect = 2e-52
Identities = 166/590 (28%), Positives = 260/590 (44%), Gaps = 57/590 (9%)
Query: 577 WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKI 636
W K+G L P IK++ + L + V D DY+ E + + SA + ++K+
Sbjct: 13024 WKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATI---KLKV 13080
Query: 637 DFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPAR 696
LD PG P V + NK+ D + + W+ + G
Sbjct: 13081 ------------LDKPG--PPASVKI--NKMYSDRAM-------LSWEPPLEDGGS---- 13113
Query: 697 PAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNP 756
+ ++ DK+ +V T + +VE + E + + +N
Sbjct: 13114 ----------EITNYIVDKRETSRPNW-AQVSATVPITSCSVEKLIEGHEYQFRICAENK 13162
Query: 757 VGEDQVNLTVKVI-----DVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERK 811
G T I D P P ISN+ +D TV W+PPA DGG PI GY+LE++
Sbjct: 13163 YGVGDPVFTEPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKR 13222
Query: 812 KKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQ------PFM 865
+ ++ W ++N I E + +A + EG YE RV A+N G +PS AS+ P
Sbjct: 13223 ETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQY 13282
Query: 866 PIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAA-LQGLT 924
P GPP+ P V D + ++VSL W P G + GY VE WV L
Sbjct: 13283 PPGPPAFP---KVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNL 13339
Query: 925 EHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQ 984
+ T V L + FRV A N G P + ++IL P +L LR+T+
Sbjct: 13340 QKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLI 13399
Query: 985 KKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGE-EVSIRNSPTDTILFIRAARRVHSGTY 1043
+ G + L +P +G+P P++TW+K L + I+++ DT L + +G Y
Sbjct: 13400 LRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKY 13459
Query: 1044 QVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQ 1103
+T+ + + T+V++V+D P PP ++ V + + + W+PP G + + Y VQ
Sbjct: 13460 ILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQ 13519
Query: 1104 KADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAAT 1153
K D + W TV +T V L G Y+FRVF++N G D T
Sbjct: 13520 KRDAERKSWSTVTTECSKTSFRVANLEEGKSYFFRVFAENEYGIGDPGET 13569
Score = 204 bits (519), Expect = 4e-52
Identities = 155/574 (27%), Positives = 256/574 (44%), Gaps = 43/574 (7%)
Query: 632 MEVKIDFVPRQEPPKIHLDCPGRIPD---TIVVVAGNKL-----RLDVPISGDPAPTVIW 683
+++ + V R E K L P + + T V A N+L + V + P+P
Sbjct: 9141 LQITKEEVSRSEA-KTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPR-- 9197
Query: 684 QKAITQGNKAPARPAPDAPEDTGDSD--EWVFDKKLLCETEGR-VRVETTKDRSIFTVEG 740
A+T DAP D G S+ +V DK+ + V T + +
Sbjct: 9198 NLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWK 9257
Query: 741 AEKEDEGVYTVTVKNPVGEDQVNLTVKVI-----DVPDAPAAPKISNVGEDSCTVQWEPP 795
+ + V N G + KV+ +P P PK+ + S V W PP
Sbjct: 9258 LIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPP 9317
Query: 796 AYDGGQPILGYILERKKKKSYRWMRLNFDLIQELS-----HEARRMIEGVVYEMRVYAVN 850
+GG PI GY LE++++ S W R++ I ++ R++EGV Y+ R A+N
Sbjct: 9318 LDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAIN 9377
Query: 851 AIGMSRPSPASQPFM---PIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVE 907
A G+ PS S P + PI PP P+ V+D + +++SL W+PP + G + GY VE
Sbjct: 9378 AAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVE 9437
Query: 908 YCPEGCSEW--VAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQ 965
EG ++W V L +V +L + FRV+A N AG P TT +
Sbjct: 9438 MQEEGTTDWKRVNEPDKLITTCECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPAT 9497
Query: 966 EILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSP 1025
+I + P + + + + K G + + +G+P P+ +W +G+ + + + P
Sbjct: 9498 DIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIP 9557
Query: 1026 TD---------TILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTD 1076
D +++ I +R H+G Y +T + + + A ++V+D P PP+DL+V+D
Sbjct: 9558 EDAQLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDLKVSD 9617
Query: 1077 AWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYY 1136
+ L WK P D G + GY ++K W V T VVP+L+ Y+
Sbjct: 9618 ITRGSCRLSWKMPDDDGGDRIKGYVIEKRTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYF 9677
Query: 1137 FRVFSQNMVGFSD-----RAATTKEPVFIPRPGI 1165
FRV ++N G + T ++P++ P P I
Sbjct: 9678 FRVRAENRFGIGPPVETIQRTTARDPIYPPDPPI 9711
Score = 203 bits (516), Expect = 1e-51
Identities = 156/577 (27%), Positives = 241/577 (41%), Gaps = 75/577 (12%)
Query: 659 IVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLL 718
I+V+ G KL + VP P PTV W K D E
Sbjct: 8091 IIVIEGEKLSIPVPFRAVPVPTVSWHK---------------------DGKE-------- 8121
Query: 719 CETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAP 778
+ R+ ++ + V + + D G+YT+T++N +G ++ VKVI +P
Sbjct: 8122 VKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKDI 8181
Query: 779 KISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIE 838
K S++ + SC + WEPP +DGG PIL Y+LER++ ++ + +LS + +I
Sbjct: 8182 KASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPV-MSGENKLSWTVKDLIP 8240
Query: 839 GVVYEMRVYAVNAIGMSRPSPASQPFM---PIGPPSEPTHLAVEDVSDTTVSLKWRPPER 895
Y RV AVN +G P + P PP P + V + + +++ W+PP
Sbjct: 8241 NGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITWKPPLY 8300
Query: 896 VGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAP 955
G + GY +E +G W + L + K L G FRVRA N AG P
Sbjct: 8301 DGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTYTAKGLEEGKEYQFRVRAENAAGISEP 8360
Query: 956 VTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLA 1015
T P + + P++ L R +++ K G+ + L G P P +TW K+ +
Sbjct: 8361 SRATPPTKAVDPIDAPKVIL----RTSLEVKRGDEIALDASISGSPYPTITWIKDENVIV 8416
Query: 1016 GEEVSIRNSPT------------------------------DTILFIRAARRVHSGTYQV 1045
EE+ R +P ++ L +R + R G Y +
Sbjct: 8417 PEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMI 8476
Query: 1046 TVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKA 1105
V ++ KA + V+D P PP + D +V +W+PP D G +E+ YT++K
Sbjct: 8477 KVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCKWEPPLDDGGSEIINYTLEKK 8536
Query: 1106 D--KKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVG----FSDRAATTKEPVF 1159
D K EW V R V +LI G Y FRV ++N G + K+P F
Sbjct: 8537 DKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKPLVAKDP-F 8595
Query: 1160 IPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGY 1196
P P +P S + +P N S I GY
Sbjct: 8596 GP-PDAPDKPIVEDVTSNSMLVKWNEPKDNGSPILGY 8631
Score = 202 bits (514), Expect = 2e-51
Identities = 143/504 (28%), Positives = 223/504 (44%), Gaps = 23/504 (4%)
Query: 727 VETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGE----DQVNLTVKV-IDVPDAPAAPKIS 781
V T R++ V +E + + +N G D +TVK+ P P+ P ++
Sbjct: 20315 VSATVARTMMKVMKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVT 20374
Query: 782 NVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVV 841
NV +S TV W P +GG ++GY LE K + S W + N +I+ + + G++
Sbjct: 20375 NVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLI 20434
Query: 842 YEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGL 901
YE RVYA NA G+ +PS S+P + I P ++ + D+S +VSL W+ P G +
Sbjct: 20435 YEFRVYAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKI 20494
Query: 902 DGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGP-GAPVTTTE 960
GY VE W A T ++ L ++ FRV A N G P
Sbjct: 20495 TGYIVERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVG 20554
Query: 961 PVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPL-AGEEV 1019
P+T + P + LP + ++ + G V L GKP P + W K+ + L V
Sbjct: 20555 PITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALV 20614
Query: 1020 SIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPP-QDLRVTDAW 1078
+ N+ + I+ A R++SG Y++ +R AT+ +Q++DKP PP +
Sbjct: 20615 CVENTTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVT 20674
Query: 1079 GLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFR 1138
+ L W+PP D G ++ Y V+K + + W V EH ++I GN Y FR
Sbjct: 20675 AEKITLLWRPPADDGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFR 20734
Query: 1139 VFSQNMVGF-----SDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVN-RSV 1192
V + N G SD V PGI P K S +++P+ + S
Sbjct: 20735 VRAVNKYGIGEPLESDSVVAKNAFVTPGPPGI---PEVTKITKNSMTVVWSRPIADGGSD 20791
Query: 1193 IAGYTAMLCCAVRGSPKPKISWFK 1216
I+GY + K + WFK
Sbjct: 20792 ISGY------FLEKRDKKSLGWFK 20809
Score = 202 bits (513), Expect = 2e-51
Identities = 144/471 (30%), Positives = 207/471 (43%), Gaps = 23/471 (4%)
Query: 683 WQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAE 742
W+ + G + + T EW+ L + V +F V
Sbjct: 8517 WEPPLDDGGSEIINYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAEN 8576
Query: 743 KEDEGVYTVT----VKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYD 798
+ G V+ K+P G PDAP P + +V +S V+W P D
Sbjct: 8577 RFGPGPPCVSKPLVAKDPFGP------------PDAPDKPIVEDVTSNSMLVKWNEPK-D 8623
Query: 799 GGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPS 858
G PILGY LE+++ S W R+N L+ L ++EG+ Y RV A NA G + S
Sbjct: 8624 NGSPILGYWLEKREVNSTHWSRVNKSLLNALKANVDGLLEGLTYVFRVCAENAAGPGKFS 8683
Query: 859 PASQP---FMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSE 915
P S P PI PP P V D S TT+ L+W PP G G + GY V+ G +E
Sbjct: 8684 PPSDPKTAHDPISPPGPPIP-RVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNE 8742
Query: 916 WVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQL 975
W + + + VK++ GA RV A N AG G P T+PVTV E + P ++L
Sbjct: 8743 WSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGEGPP-GETQPVTVAEPQEPPAVEL 8801
Query: 976 PRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAA 1035
++ IQ G+ + + G+P P WTKE L + V I N T + L I+ A
Sbjct: 8802 DVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGTKSELIIKDA 8861
Query: 1036 RRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNT 1095
R G Y +T A ++V D P P DL+ L W P+D G +
Sbjct: 8862 LRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGS 8921
Query: 1096 ELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVG 1146
E+ G+ +++ D K W +E R+ C + L+ G Y FRV ++N G
Sbjct: 8922 EITGFIIERKDAKMHTWRQPIE-TERSKCDITGLLEGQEYKFRVIAKNKFG 8971
Score = 201 bits (512), Expect = 3e-51
Identities = 169/574 (29%), Positives = 245/574 (42%), Gaps = 58/574 (10%)
Query: 642 QEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDA 701
QEPP + LD + I ++AG LR+ ++G P PT +W K
Sbjct: 8794 QEPPAVELDVS--VKGGIQIMAGKTLRIPAVVTGRPVPTKVWTK---------------- 8835
Query: 702 PEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQ 761
+E DK RV ++ +S ++ A ++D G Y +T N G
Sbjct: 8836 -------EEGELDKD-------RVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKF 8881
Query: 762 VNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRL 821
V+V DVP K C + W P DGG I G+I+ERK K + W +
Sbjct: 8882 AAARVEVFDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFIIERKDAKMHTWRQ- 8940
Query: 822 NFDLIQELSH-EARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PIGPPSEPTHLA 877
+ E S + ++EG Y+ RV A N G P P + P+GPP+ P L
Sbjct: 8941 --PIETERSKCDITGLLEGQEYKFRVIAKNKFGCGPPVEIG-PILAVDPLGPPTSPERLT 8997
Query: 878 VEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTG 937
+ + +T++L W+ P G + GY +E ++ + L TS LV++L
Sbjct: 8998 YTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEH 9057
Query: 938 ARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLR-QTIQKKVGEPVNLLIP 996
FRV+A N G P V +Q+ P ++L +R TI+ K GEPV++
Sbjct: 9058 QMYEFRVKAVNEIGESEPSLPLN-VVIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPAD 9116
Query: 997 FQGKPRPQVTWTK---------EGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTV 1047
G P P++ W+K + + EEVS S T L I A R GTY VT
Sbjct: 9117 VTGLPMPKIEWSKNETVIEKPTDALQITKEEVS--RSEAKTELSIPKAVREDKGTYTVTA 9174
Query: 1048 RIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKAD- 1106
+ ++V D+PSPP++L VTD + L W P D G +E+ Y + K D
Sbjct: 9175 SNRLGSVFRNVHVEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDA 9234
Query: 1107 -KKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIP--RP 1163
+K EW V + +LI Y FRV + N G SD + K + P P
Sbjct: 9235 SRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLP 9294
Query: 1164 GITYEPPNYKALDFSEAPSFTQPLVN-RSVIAGY 1196
G +P S S+T PL N S I GY
Sbjct: 9295 GPPGKPKVLARTKGSMLVSWTPPLDNGGSPITGY 9328
Score = 201 bits (511), Expect = 4e-51
Identities = 166/600 (27%), Positives = 260/600 (43%), Gaps = 71/600 (11%)
Query: 577 WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKI 636
W K GK++ P +++ LTI T D +Y+ K+ ++V +
Sbjct: 14108 WSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATN---PFGTKVEHVKVTV 14164
Query: 637 DFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPAR 696
LDVP G P P I + KA
Sbjct: 14165 --------------------------------LDVP--GPPGPVEI---SNVSAEKATLT 14187
Query: 697 PAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKD----RSIFT--VEGAEKEDEGVYT 750
P + ++ +K+ ET + ++D R + T ++G +E ++
Sbjct: 14188 WTPPLEDGGSPIKSYILEKR---ETSRLLWTVVSEDIQSCRHVATKLIQG----NEYIFR 14240
Query: 751 VTVKNPVGEDQV--NLTVKVID---VPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILG 805
V+ N G+ + + VK++D P P P++SNV +++ TV W+ P DGG I G
Sbjct: 14241 VSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITG 14300
Query: 806 YILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM 865
Y +ER++KKS RW+R + +L + + EG YE RV A N G+ PS AS +
Sbjct: 14301 YHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVL 14360
Query: 866 ------PIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAA 919
P GPPS P V D + + SL W P G + GY VE+ G W+
Sbjct: 14361 MKDAAYPPGPPSNP---HVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKD 14417
Query: 920 LQGLT-EHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRH 978
G T +V DL T + FR+ A N AG G P + V + E P +L
Sbjct: 14418 TTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVIPD-VEIVEREMAPDFELDAE 14476
Query: 979 LRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRV 1038
LR+T+ + G + + +P +G+P P+VTWTK+ L +I N+ + T+L I R
Sbjct: 14477 LRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLK-NRANIENTESFTLLIIPECNRY 14535
Query: 1039 HSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELW 1098
+G + +T+ + + ++V+D P P +LR TD +V L W P G + +
Sbjct: 14536 DTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRIT 14595
Query: 1099 GYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPV 1158
Y V+K + + T + V L G Y+FRV ++N G + TT EPV
Sbjct: 14596 NYIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETT-EPV 14654
Score = 200 bits (508), Expect = 8e-51
Identities = 169/607 (27%), Positives = 252/607 (41%), Gaps = 59/607 (9%)
Query: 574 RGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFME 633
R W K+G E+ ++++ + L + D T Y+ + + + A++ +
Sbjct: 21684 RVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEI---K 21740
Query: 634 VKIDFVPRQEPPKIHLDCPGRI--PDTIVVVAGNKLRL--DVPISGDPAPTV--IWQKAI 687
VK+ D PG++ P + G K+ L D P++ AP I +K
Sbjct: 21741 VKVQ------------DTPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRE 21788
Query: 688 TQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEG 747
T +R A ED ++ + K L+ E + RV
Sbjct: 21789 T------SRLAWALIEDKCEAQSYTAIK-LINGNEYQFRVSA------------------ 21823
Query: 748 VYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYI 807
V V P+ D V ++ VPDAP P+ SN+ +S T+ W P DGG I YI
Sbjct: 21824 VNKFGVGRPLDSDPVVAQIQYT-VPDAPGIPEPSNITGNSITLTWARPESDGGSEIQQYI 21882
Query: 808 LERKKKKSYRWMR-LNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM- 865
LER++KKS RW++ ++ I E + + EG YE V A NA G+ S S+
Sbjct: 21883 LERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKC 21942
Query: 866 --PIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGL 923
P+ PP PT + V D S TTVSL+W P G + GY +E C +W
Sbjct: 21943 REPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEA 22002
Query: 924 TEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTI 983
T V DL G FRV A N AG G T + + L P L + + +QT
Sbjct: 22003 CVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTH 22062
Query: 984 QKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTY 1043
+ G + L I +QG+P P W+K L+ I + + + L + R +G Y
Sbjct: 22063 VVRAGASIRLFIAYQGRPTPTAVWSKPDSNLS-LRADIHTTDSFSTLTVENCNRNDAGKY 22121
Query: 1044 QVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQ 1103
+TV + T ++V+D P PP + D + L W P G + Y V+
Sbjct: 22122 TLTVENNSGSKSITFTVKVLDTPGPPGPITFKDVTRGSATLMWDAPLLDGGARIHHYVVE 22181
Query: 1104 KADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRP 1163
K + W + E R V +L G YYFRV + N G EP +P P
Sbjct: 22182 KREASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVG-------EPYEMPEP 22234
Query: 1164 GITYEPP 1170
+ E P
Sbjct: 22235 IVATEQP 22241
Score = 199 bits (507), Expect = 1e-50
Identities = 128/407 (31%), Positives = 195/407 (47%), Gaps = 14/407 (3%)
Query: 771 VPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELS 830
VP P P+++ V +DS T+ W P DGG PILGY +ERK++ W ++ L+
Sbjct: 14953 VPGPPGTPQVTAVTKDSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNI 15012
Query: 831 HEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PIGPPSEPTHLAVEDVSDTTVS 887
++ + +G+ YE RV A N G S+PS S+P + PI PP +P L +++ TV+
Sbjct: 15013 FKSSGLTDGIAYEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPL---NITRHTVT 15069
Query: 888 LKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAH 947
LKW PE G + Y VE W+ A V L A FRV A
Sbjct: 15070 LKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAK 15129
Query: 948 NMAGP-GAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVT 1006
N AG P ++ +T ++ ++ P++++ + T+ K GE L G+P P +
Sbjct: 15130 NAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTME 15189
Query: 1007 WTKEGQPLAG-EEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDK 1065
W+K+G+ L G ++ I+ + T L + + R SG Y +T K ++V+D+
Sbjct: 15190 WSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDR 15249
Query: 1066 PSPPQ-DLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHC 1124
P PP+ L VT+ L W PP D G ++ Y VQK + + W V + T
Sbjct: 15250 PGPPEGPLAVTEVTSEKCVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKL 15309
Query: 1125 VVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPN 1171
V +L+ GN Y FRV + N G + EPV P Y PP+
Sbjct: 15310 KVTKLLKGNEYIFRVMAVNKYGVGE--PLESEPVLAVNP---YGPPD 15351
Score = 199 bits (506), Expect = 1e-50
Identities = 156/565 (27%), Positives = 253/565 (44%), Gaps = 26/565 (4%)
Query: 702 PEDTGDSD--EWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGE 759
P+D G S+ ++ +K+ + V + ++ F V + E + V+ +N G
Sbjct: 13795 PKDDGGSEITNYILEKRDSVNNKW-VTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGV 13853
Query: 760 DQVNLTVKVI-----DVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKK 814
+ + ++ DVPDAP P I +V DS ++ W P GG PI GY LE K++
Sbjct: 13854 GEGLKSEPIVARHPFDVPDAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERN 13913
Query: 815 SYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPT 874
S W R N I+ + + EG+ YE RV A+N G+ +PS S+P + + P P
Sbjct: 13914 SLLWKRANKTPIRMRDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPG 13973
Query: 875 HLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDL 934
V +++ +V+L W P+ G L GY VE W+ A + V DL
Sbjct: 13974 KPEVINITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDL 14033
Query: 935 PTGARLLFRVRAHNMAGP-GAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNL 993
G + FR+RA N AG AP +TE + ++ + P + L ++ + K G+ + L
Sbjct: 14034 VEGGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVL 14093
Query: 994 -LIPFQGKPRPQVTWTKEGQPLAGEEVS-IRNSPTDTILFIRAARRVHSGTYQVTVRIEN 1051
I GKP P+ +W+K G+ + +++ I ++PT ++L I+ A R +G Y +T
Sbjct: 14094 NAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPF 14153
Query: 1052 MEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTME 1111
+ + V+D P PP + +++ L W PP + G + + Y ++K + +
Sbjct: 14154 GTKVEHVKVTVLDVPGPPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLL 14213
Query: 1112 WFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPV-----FIPRPGIT 1166
W V E + V +LI GN Y FRV + N G + EPV F P PG
Sbjct: 14214 WTVVSEDIQSCRHVATKLIQGNEYIFRVSAVNHYGKGE--PVQSEPVKMVDRFGP-PGPP 14270
Query: 1167 YEPPNYKALDFSEAPSFTQPLVN-RSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDA 1225
+P + S+ +P+ + S I GY V K + W + D
Sbjct: 14271 EKPEVSNVTKNTATVSWKRPVDDGGSEITGY------HVERREKKSLRWVRAIKTPVSDL 14324
Query: 1226 RFRMFSKQGVLTLEIRKPCPFDGGI 1250
R ++ Q T E R GI
Sbjct: 14325 RCKVTGLQEGSTYEFRVSAENRAGI 14349
Score = 197 bits (500), Expect = 7e-50
Identities = 147/509 (28%), Positives = 216/509 (42%), Gaps = 42/509 (8%)
Query: 644 PPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPE 703
PP++ LD R D I V G +R+ + G P P + W K
Sbjct: 11600 PPEVELDVTCR--DVITVRVGQTIRILARVKGRPEPDITWTK------------------ 11639
Query: 704 DTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVN 763
+ K+L E RV + R ++ A + D G Y ++ KN G Q +
Sbjct: 11640 ----------EGKVLVR-EKRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSGHAQGS 11688
Query: 764 LTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNF 823
V V+D P K++NV +++CT+ WE P +GG I +I+E +K W +
Sbjct: 11689 AIVNVLDRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIVEYRKPNQKGWSIVAS 11748
Query: 824 DLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGP---PSEPTHLAVED 880
D+ + L ++ Y RV A N +G+ P + I P P EP +L + D
Sbjct: 11749 DVTKRLIKA--NLLANNEYYFRVCAENKVGVGPTIETKTPILAINPIDRPGEPENLHIAD 11806
Query: 881 VSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARL 940
T V LKWR P+ G Y VE +G +W +G + T +V
Sbjct: 11807 KGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVENQIY 11866
Query: 941 LFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGK 1000
FRV+ N G V T E V V+E LQ+P L L L + K G+ + L +GK
Sbjct: 11867 EFRVQTKNEGGESDWVKTEE-VVVKEDLQKPVLDLK--LSGVLTVKAGDTIRLEAGVRGK 11923
Query: 1001 PRPQVTWTKEGQPL---AGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKAT 1057
P P+V WTK+ V I + + A+R G Y VT A
Sbjct: 11924 PFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAY 11983
Query: 1058 LVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLE 1117
+ V+DKP P ++L++ D + W PP+D G E+ Y ++K + K M W T
Sbjct: 11984 ATVNVLDKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSA 12043
Query: 1118 HYRRTHCVVPELIIGNGYYFRVFSQNMVG 1146
V LI GN Y FRV ++N +G
Sbjct: 12044 TVLTPGTTVTRLIEGNEYIFRVRAENKIG 12072
Score = 196 bits (498), Expect = 1e-49
Identities = 146/539 (27%), Positives = 227/539 (42%), Gaps = 73/539 (13%)
Query: 635 KIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAP 694
+I V QE P+I LD ++ + V AG K+ L ++G P P + W KA
Sbjct: 7373 EIQAVDTQEAPEIFLDV--KLLAGLTVKAGTKIELPATVTGKPEPKITWTKA-------- 7422
Query: 695 ARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVK 754
++ + + R+ +E +S T+ +++ D G Y +
Sbjct: 7423 ---------------------DMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAV 7461
Query: 755 NPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKK 814
N G + V V+D P PAA I++V +SC + W PP DGG I Y++ER+
Sbjct: 7462 NVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATD 7521
Query: 815 SYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRP---SPASQPFMPIGPPS 871
S W +L+ +++ + +A ++I Y RV A N G+ P SP + + PP
Sbjct: 7522 SEVWHKLS-STVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITAKYQ-FDPPG 7579
Query: 872 EPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILV 931
PT L D++ V+L W P+ G + GY VE +WV + + T+ V
Sbjct: 7580 PPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRV 7639
Query: 932 KDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPV 991
K L + FRV A N+AGPG P +TEP+ +++ + P P
Sbjct: 7640 KGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPP----------------WPPG 7683
Query: 992 NLLIPFQGKPRPQVTWTKEGQPLAG--EEVSIRNSPTDTILFIRAARRV----------- 1038
+ GK ++ WTK E I T T ++R A V
Sbjct: 7684 KPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVPTTQHLLPGLM 7743
Query: 1039 HSGTYQVTVRIENMEDKA--------TLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQ 1090
Y VR N ++ L + + PSPP+ L V + L+W P+
Sbjct: 7744 EGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPE 7803
Query: 1091 DVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSD 1149
G + + Y V+K D + W TV + T C V L G+ Y FRV ++N +G SD
Sbjct: 7804 KDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSD 7862
Score = 196 bits (498), Expect = 1e-49
Identities = 162/633 (25%), Positives = 260/633 (41%), Gaps = 83/633 (13%)
Query: 642 QEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDA 701
QE P++ +D + D +V AG+++R+ I G P P W+ + KA D
Sbjct: 9500 QEEPEVFIDIGAQ--DCLVCKAGSQIRIPAVIKGRPTPKSSWEFD-GKAKKAMKDGVHDI 9556
Query: 702 PEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQ 761
PED ++ET ++ S+ + ++ G Y++T KN G+
Sbjct: 9557 PEDA--------------------QLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKT 9596
Query: 762 VNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRL 821
N VKV+DVP P K+S++ SC + W+ P DGG I GY++E++ W ++
Sbjct: 9597 ANCRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKRTIDGKAWTKV 9656
Query: 822 NFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PIGPPSEPTHLAV 878
N D + ++ Y RV A N G+ P Q PI PP P L +
Sbjct: 9657 NPDC-GSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKI 9715
Query: 879 EDVSDTTVSLKWRPPERVGAGGLDGYSVE---YCPEGCSE--WVAALQGLTEHTSILVKD 933
++ TV L W+PP+ G + Y VE + P G + W + E V+D
Sbjct: 9716 GLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVED 9775
Query: 934 LPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNL 993
L G FRV+A N AG P T P Q RP + L++ ++ + G VN+
Sbjct: 9776 LVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQ----RPDMPPSIDLKEFMEVEEGTNVNI 9831
Query: 994 LIPFQGKPRPQVTWTK-------EGQPLAGEEVSIRNSPTDTI-LFIRAARRVHSGTYQV 1045
+ +G P P +TW K +P+ + + DT L I +RR +G Y +
Sbjct: 9832 VAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTI 9891
Query: 1046 TVRIENMEDKATLVLQVVDKPSPPQD-LRVTDAWGLNVALEWKPPQDVGNTELWGYTVQK 1104
T + L V+ +P PP ++ + L W PP+D G +++ Y ++K
Sbjct: 9892 TAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIEK 9951
Query: 1105 ADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPV--FIPR 1162
+ W V + +P+L+ G+ Y FR+ +QN G + + E
Sbjct: 9952 REANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFSV 10011
Query: 1163 PG----------------ITYEPPNYKA--------LDFSEAPSFTQPLVNRSVIAGYTA 1198
PG + +E P Y L+ + S VNR I T
Sbjct: 10012 PGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMTL 10071
Query: 1199 MLCCAVRGSPKPKISWFKNGLDLGEDARFRMFS 1231
+S+ GL G D +FR+++
Sbjct: 10072 ------------GVSYKVTGLIEGSDYQFRVYA 10092
Score = 195 bits (495), Expect = 3e-49
Identities = 127/403 (31%), Positives = 185/403 (45%), Gaps = 20/403 (4%)
Query: 772 PDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSH 831
P P+ P++S + +DS V W P DGG I GYILE++ K+ RW + N + +L
Sbjct: 18597 PGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLTDLRL 18656
Query: 832 EARRMIEGVVYEMRVYAVNAIGMSRPSP------ASQPFMPIGPPSEPTHLAVEDVSDTT 885
+ EG YE RV A NA G+ PS A P GPPS P V D S ++
Sbjct: 18657 RVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNP---KVTDTSRSS 18713
Query: 886 VSLKWRPPERVGAGGLDGYSVEYCPEGCSEWV-----AALQGLTEHTSILVKDLPTGARL 940
VSL W P G + GY VE EW LQG V L
Sbjct: 18714 VSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQG----KQFTVTKLKENTEY 18769
Query: 941 LFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGK 1000
FR+ A N G G P T V QE ++ P ++L LR+ + + + L + +G+
Sbjct: 18770 NFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRASATLRLFVTIKGR 18829
Query: 1001 PRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVL 1060
P P+V W K + + + I + + T+L I R SG Y +T+ + A + +
Sbjct: 18830 PEPEVKWEK-AEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSGSKTAFVNV 18888
Query: 1061 QVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYR 1120
+V+D PS P +L + + +V L W+PP G ++ Y V+K + + T+ +
Sbjct: 18889 RVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATITNNCT 18948
Query: 1121 RTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRP 1163
+T + L G YYFRV + N G A TT EPV + P
Sbjct: 18949 KTTFRIENLQEGCSYYFRVLASNEYGIGLPAETT-EPVKVSEP 18990
Score = 191 bits (485), Expect = 4e-48
Identities = 129/467 (27%), Positives = 213/467 (45%), Gaps = 18/467 (3%)
Query: 772 PDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSH 831
P P P + + +DS +QW P +GG P++GY LERK++ S W ++N +I +
Sbjct: 17118 PGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQF 17177
Query: 832 EARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PIGPPSEPTHLAVEDVSDTTVSL 888
+A+ + EG+ YE RVYA N +G+ + S S+ ++ P PP P + V+ ++L
Sbjct: 17178 KAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPPGTPEPIMVK---RNEITL 17234
Query: 889 KWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHN 948
+W P G + GY VE W+ A T V L R FRV A N
Sbjct: 17235 QWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKN 17294
Query: 949 MAGP-GAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTW 1007
AG P +T P+T ++ ++ PR+ + R TI GE L GKP P + W
Sbjct: 17295 AAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEW 17354
Query: 1008 TKEGQPL-AGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKAT--LVLQVVD 1064
+ + + I+N+ +L ++ A R+ G Y +R N+ + + ++V+D
Sbjct: 17355 LRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQY--ILRASNVAGSKSFPVNVKVLD 17412
Query: 1065 KPSPPQ-DLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTH 1123
+P PP+ ++VT +L W PP G +++ Y V+K + + W V
Sbjct: 17413 RPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNS 17472
Query: 1124 CVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSF 1183
V +L+ GN Y FR+ + N G + + PV + P + PP K+L+ +
Sbjct: 17473 LKVTKLLEGNEYVFRIMAVNKYGVGEPLESA--PVLMKNPFVLPGPP--KSLEVTNIAKD 17528
Query: 1184 TQPLV-NRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRM 1229
+ + NR G + ++ V + I W K D R R+
Sbjct: 17529 SMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRV 17575
Score = 189 bits (480), Expect = 1e-47
Identities = 125/408 (30%), Positives = 194/408 (47%), Gaps = 15/408 (3%)
Query: 771 VPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELS 830
VP P P ++ DS VQW P DGG ++GY LERK++ S W++LN I +
Sbjct: 16035 VPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTK 16094
Query: 831 HEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PIGPPSEPTHLAVEDVSDTTVS 887
+ + EGV YE RV A N +G+ +PS S+ ++ P PP P + V+ +V+
Sbjct: 16095 FKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAII---VTRNSVT 16151
Query: 888 LKWRPPERVGAGGLDGYSVE--YCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVR 945
L+W+ P G + GY VE PEG W+ A T V L R FRV
Sbjct: 16152 LQWKKPTYDGGSKITGYIVEKKELPEG--RWMKASFTNIIDTHFEVTGLVEDHRYEFRVI 16209
Query: 946 AHNMAGP-GAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQ 1004
A N AG P +T +T ++ + PR+ + + TI GE + GKP P
Sbjct: 16210 ARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPT 16269
Query: 1005 VTWTKEGQPLAG-EEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVV 1063
+ W K Q L+ + I+++ T L ++ A RV SG Y + + E T+ ++V+
Sbjct: 16270 IQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVL 16329
Query: 1064 DKPSPPQ-DLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRT 1122
D+P PP+ + ++ L WKPP G +++ Y V++ + + W V + +
Sbjct: 16330 DRPGPPEGPVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTL 16389
Query: 1123 HCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPP 1170
C V +L+ GN Y FR+ + N G + EPV P + + P
Sbjct: 16390 SCKVTKLLEGNEYTFRIMAVNKYGVGE--PLESEPVVAKNPFVVPDAP 16435
Score = 189 bits (479), Expect = 2e-47
Identities = 129/478 (26%), Positives = 224/478 (46%), Gaps = 24/478 (5%)
Query: 743 KEDEGVYTVTVKNPVG-----EDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAY 797
K +E ++ V N G E + + +P P P+ G++ +QW P
Sbjct: 22901 KNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPES 22960
Query: 798 DGGQPILGYILERKKKKSYRWMRLNFD-LIQELSHEARRMIEGVVYEMRVYAVNAIGMSR 856
DGG I Y++++++KKS RW R+N D ++ + + ++EG Y+ RV AVNA G S
Sbjct: 22961 DGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSE 23020
Query: 857 PSPAS------QPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCP 910
PS AS +P GPPS P V D + ++SL W P G + GY +E
Sbjct: 23021 PSEASNFISCREPSYTPGPPSAPR---VVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQE 23077
Query: 911 EGCSEWVAALQGLT-EHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQ 969
+ +W T +T V DL G + FRV A N+ G + + E ++
Sbjct: 23078 KDTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIE 23137
Query: 970 RPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTI 1029
P L+L L++T+ + G + L++ G+P P +TW+K+G LA + I + + ++
Sbjct: 23138 IPDLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAI-IDTTESYSL 23196
Query: 1030 LFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPP 1089
L + R +G Y + ++ + AT++++V D P P ++V + +V + W+ P
Sbjct: 23197 LIVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIP 23256
Query: 1090 QDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSD 1149
G + Y V+K + + TV +T + L+ G YYFRV +N+ G +
Sbjct: 23257 TIDGGAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGE 23316
Query: 1150 RAATTKEPVFIPRPGITYEPPNYKALDFSEAP---SFTQPLVN-RSVIAGYTAMLCCA 1203
T+ + P + P + +D +++ ++ +PL + S + GY C A
Sbjct: 23317 PCETSDAVLVSEVPLV---PAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKA 23371
Score = 188 bits (477), Expect = 3e-47
Identities = 139/490 (28%), Positives = 224/490 (45%), Gaps = 24/490 (4%)
Query: 700 DAPEDTGDSDEWVF--DKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPV 757
D PED G + + +K+ +T ++ V ++ R+ F V K+ E + V +N
Sbjct: 21374 DVPEDNGGGEITCYSIEKRETSQTNWKM-VCSSVARTTFKVPNLVKDAEYQFRVRAENRY 21432
Query: 758 GEDQVNLTVKVID-----VPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKK 812
G Q ++ ++ +P P P I NV D ++ W+ P YDGG + G+ +E+K+
Sbjct: 21433 GVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKE 21492
Query: 813 KKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQ---PFMPIGP 869
+ S W ++N I + A ++EG+ Y+ RVYA N+ G+S PS S+ P+ P
Sbjct: 21493 RNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDP 21552
Query: 870 PSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSI 929
P P ++ DV+ T++LKW PP R G + GYS+E +G WV
Sbjct: 21553 PGTPDYI---DVTRETITLKWNPPLRDGGSKIVGYSIEK-RQGNERWVRCNFTDVSECQY 21608
Query: 930 LVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTV-QEILQRPRLQLPRHLRQTIQKKVG 988
V L G R FR+ A N G +P + + + + ++ P ++ + K G
Sbjct: 21609 TVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSG 21668
Query: 989 EPVNLLIPFQGKPRPQVTWTKEGQPLAGE-EVSIRNSPTDTILFIRAARRVHSGTYQVTV 1047
E + + QG+P P+VTW K+G + + I + T LF+R A R H G Y V
Sbjct: 21669 ESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEA 21728
Query: 1048 RIENMEDKATLVLQVVDKPSP-PQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKAD 1106
+ + KA + ++V D P +R T+ G + L W P + G + Y ++K +
Sbjct: 21729 KNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRE 21788
Query: 1107 KKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGF-----SDRAATTKEPVFIP 1161
+ W + + +LI GN Y FRV + N G SD +
Sbjct: 21789 TSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPD 21848
Query: 1162 RPGITYEPPN 1171
PGI EP N
Sbjct: 21849 APGIP-EPSN 21857
Score = 185 bits (469), Expect = 3e-46
Identities = 224/932 (24%), Positives = 347/932 (37%), Gaps = 158/932 (16%)
Query: 374 QVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAA 433
+V + ++ E+ A+ KW +N + I SKYI TL I L D A
Sbjct: 6345 RVKEQQEVVFNCEVNTEGAKAKWFRNEEAI-FDSSKYIILQKDLVYTLRIRDAHLDDQAN 6403
Query: 434 YQCVVGGE-----KCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLK 488
Y + K + L V+E + I PL+D M + V F C+V+ +KW K
Sbjct: 6404 YNVSLTNHRGENVKSAANLIVEEEDLRIVEPLKDIETMEKKSVTFWCKVNRLNVTLKWTK 6463
Query: 489 DGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVY 548
+G E+ + YR K +H L I + D G Y + +++AEL++ E E
Sbjct: 6464 NGEEVPFDNRVSYRVDK--YKHMLTIKDCGFPDEGEYIVTAGQDKSVAELLIIEAPTEFV 6521
Query: 549 QSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTP 608
+ + D V D AVF C++S E W +NG+E+ + K G +H+L I D
Sbjct: 6522 EHLEDQTVTEFDDAVFSCQLSREKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDCRL 6581
Query: 609 ADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLR 668
DE +Y+ E A+L E+ ++ + PP+ L+ PG D + + NK +
Sbjct: 6582 DDECEYACGVEDRKSR--ARLFVEEIPVEII---RPPQDILEAPGA--DVVFLAELNKDK 6634
Query: 669 LDVPISGDPAPTVIWQK---AITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRV 725
++V W + + QG+K E + +C+ + R
Sbjct: 6635 VEVQ----------WLRNNMVVVQGDKHQMM------------SEGKIHRLQICDIKPR- 6671
Query: 726 RVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGE 785
D+G Y K+ ++ L AAPKI +
Sbjct: 6672 -------------------DQGEYRFIAKDKEARAKLELA----------AAPKIKTADQ 6702
Query: 786 DSCTVQWEPPAYDGGQPILGYI-LERKKKKSYRWMRLNFDLIQEL-----SHEARRMIEG 839
D D G+P+ + + K W + N L + + R++E
Sbjct: 6703 DLVV--------DVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKTIDTTAEQTSFRILEA 6754
Query: 840 VVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAG 899
+ Y + + I P +L V + D VSL W P G
Sbjct: 6755 KKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDGEVSLAWEEPLTDGGS 6814
Query: 900 GLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGA-RLLFRVRAHNMAGPGAPVTT 958
+ GY VE WV A E V L G LFRV A N G G PV T
Sbjct: 6815 KIIGYVVERRDIKRKTWVLATDR-AESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVET 6873
Query: 959 TEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKE----GQPL 1014
PV R + +P G P+N+ I + +TW G +
Sbjct: 6874 DNPVEA-----RSKYDVP-----------GPPLNVTITDVNRFGVSLTWEPPEYDGGAEI 6917
Query: 1015 AGEEVSIRNSPT---DTILFIRAARR-------VHSGTYQVTVRIENM-----EDKATLV 1059
+ +R+ + DT + +RA V Y VR +N AT
Sbjct: 6918 TNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPF 6977
Query: 1060 LQVVD---KPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVL 1116
++V D +PSPP +L +D +V L+W+PP G + + GY +++ ++ W
Sbjct: 6978 VKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWI--- 7034
Query: 1117 EHYRRTHCVVPELII-------GNGYYFRVFSQNMVGFSDRAAT----TKEPVFIPRPGI 1165
R +VPEL GN Y +RV ++N G SD + T + F+
Sbjct: 7035 ---RCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFV----- 7086
Query: 1166 TYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDA 1225
EP +D S +F L VI + G P+P +W L
Sbjct: 7087 --EP----TMDLS---AFKDGL---EVIVPNPITILVPSTGYPRPTATWCFGDKVLETGD 7134
Query: 1226 RFRMFSKQGVLTLEIRKPCPFDGGIYVCRATN 1257
R +M + L I D GIY + N
Sbjct: 7135 RVKMKTLSAYAELVISPSERSDKGIYTLKLEN 7166
Score = 184 bits (467), Expect = 5e-46
Identities = 128/483 (26%), Positives = 224/483 (46%), Gaps = 20/483 (4%)
Query: 702 PEDTGDSD--EWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVG- 758
PE G S ++ +K+ + +G V+TT + TV + V+ V +N +G
Sbjct: 7802 PEKDGGSPITNYIVEKRDV-RRKGWQTVDTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQ 7860
Query: 759 ------EDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKK 812
ED V L P P A + +V + ++WEPP DGG+PI Y++E+K+
Sbjct: 7861 SDYTEIEDSV-LAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKE 7919
Query: 813 KKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PIGP 869
+ RW++ + + +IEG + +V A N G+ PS ++ P P
Sbjct: 7920 RLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSP 7979
Query: 870 PSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSI 929
PS P L V D +++ W+PPE+ G + GY VE CP G +W+ +
Sbjct: 7980 PSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKF 8039
Query: 930 LVKD-LPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVG 988
V++ + + RVRA N G P +E V ++ +P + L H I+ G
Sbjct: 8040 KVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHDIIVIE---G 8096
Query: 989 EPVNLLIPFQGKPRPQVTWTKEGQPL-AGEEVSIRNSPTDTILFIRAARRVHSGTYQVTV 1047
E +++ +PF+ P P V+W K+G+ + A + ++++N L + + R +G Y +T+
Sbjct: 8097 EKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITL 8156
Query: 1048 RIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADK 1107
+ A++ ++V+ P P +D++ +D + L W+PP+ G T + Y +++ +
Sbjct: 8157 ENKLGSATASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREA 8216
Query: 1108 KTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITY 1167
+ V+ + V +LI Y+FRV + N VG K PV P
Sbjct: 8217 GRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVG-GGEYIELKNPVIAQDPKQPP 8275
Query: 1168 EPP 1170
+PP
Sbjct: 8276 DPP 8278
Score = 183 bits (465), Expect = 8e-46
Identities = 119/406 (29%), Positives = 184/406 (45%), Gaps = 15/406 (3%)
Query: 772 PDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSH 831
P P P ++++ +D VQW P DGG I+GY LE+K+K S W++LN IQ+
Sbjct: 18200 PGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKF 18259
Query: 832 EARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PIGPPSEPTHLAVEDVSDTTVSL 888
+ + EG+ YE +V A N +G+ +PS S+ F+ P PP P + ++ V+L
Sbjct: 18260 KTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAIV---ITRNNVTL 18316
Query: 889 KWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHN 948
KW+ P G + GY VE W+ A T V L R FRV A N
Sbjct: 18317 KWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGLVEDQRYEFRVIARN 18376
Query: 949 MAGP-GAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTW 1007
AG P ++ +T ++ + P L + I GE L +GKP P V W
Sbjct: 18377 AAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVW 18436
Query: 1008 TKEGQPL--AGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDK 1065
+K+G+ L + I+++ T L ++ R G Y + + + ++V+D+
Sbjct: 18437 SKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDR 18496
Query: 1066 PSPPQ-DLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHC 1124
P PP+ L+VT L W PP G + Y ++K + + W V + +
Sbjct: 18497 PGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLSWTQVSTEVQALNY 18556
Query: 1125 VVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPP 1170
V +L+ GN Y FRV + N G + PV P Y+PP
Sbjct: 18557 KVTKLLPGNEYIFRVMAVNKYGIGE--PLESGPVTACNP---YKPP 18597
Score = 183 bits (465), Expect = 8e-46
Identities = 149/599 (24%), Positives = 245/599 (40%), Gaps = 43/599 (7%)
Query: 577 WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKI 636
W K+G+ L +R+ VS V L+I + + D Y A +++ + + I
Sbjct: 19123 WRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSIT-----VPITI 19177
Query: 637 DFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPAR 696
+ R PP +R+D +S D T+ W G +
Sbjct: 19178 IVLDRPGPP-------------------GPIRID-EVSCDSI-TISWNPPEYDGGCQISN 19216
Query: 697 PAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNP 756
+ E T S W + + T ++ TT F V + + Y+
Sbjct: 19217 YIVEKKETT--STTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYS------ 19268
Query: 757 VGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSY 816
E + P P PK+ + + + V W+ P DGG ++GY LE K++ S
Sbjct: 19269 --ESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSI 19326
Query: 817 RWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHL 876
W + N LI + + + EG++YE RVYA N G+ + S + +P P P
Sbjct: 19327 LWSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQP 19386
Query: 877 AVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPT 936
V +++ +VSLKW P G + GY VE W+ + T V +L
Sbjct: 19387 EVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQETYFEVTELTE 19446
Query: 937 GARLLFRVRAHNMA-GPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLI 995
R FRV A N A P +T P+ V++ ++ PR+ + R I K GE + +
Sbjct: 19447 DQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINA 19506
Query: 996 PFQGKPRPQVTWTKEGQPLAGE-EVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMED 1054
G+P P ++W K+G + I ++ T+L ++ R +G Y +T++
Sbjct: 19507 DIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTR 19566
Query: 1055 KATLVLQVVDKPSPPQ-DLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWF 1113
+ +V+DKP PP L + +L W PQ+ G ++ Y V+K + + W
Sbjct: 19567 SVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQEDGGADIDYYIVEKRETSHLAWT 19626
Query: 1114 TVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDR----AATTKEPVFIPRPGITYE 1168
+ T C V +L+ GN Y FRV N G + A +P +P P + E
Sbjct: 19627 ICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLE 19685
Score = 182 bits (462), Expect = 2e-45
Identities = 114/380 (30%), Positives = 178/380 (46%), Gaps = 5/380 (1%)
Query: 771 VPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELS 830
+P P + +++N+ +DS TV W P DGG I+GYI+E++ + RW++ N I +L
Sbjct: 17513 LPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLR 17572
Query: 831 HEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PIGPPSEPTHLAVEDVSDTTVS 887
+ E YE RV A NA G+ PSPA+ + P+ P PT+ + D + +++
Sbjct: 17573 LRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHIVDTTKNSIT 17632
Query: 888 LKWRPPERVGAGGLDGYSVEYCPEGCSEW-VAALQGLTEHTSILVKDLPTGARLLFRVRA 946
L W P G + GY VE C EW + Q T + L RV A
Sbjct: 17633 LAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCA 17692
Query: 947 HNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVT 1006
N G G + V ++ L+ P L L LR+ I + G + IPF+G+P P++T
Sbjct: 17693 LNKVGLGEATSVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGSARIHIPFKGRPTPEIT 17752
Query: 1007 WTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKP 1066
W++E ++V I T L I R +G Y + + + A + ++V+D P
Sbjct: 17753 WSREEGEFT-DKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTP 17811
Query: 1067 SPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVV 1126
PPQ+L V + + L W+PP G ++ Y + K + + V +T V
Sbjct: 17812 GPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKV 17871
Query: 1127 PELIIGNGYYFRVFSQNMVG 1146
L G YYFRV ++N G
Sbjct: 17872 ENLTEGAIYYFRVMAENEFG 17891
Score = 180 bits (456), Expect = 9e-45
Identities = 116/381 (30%), Positives = 183/381 (48%), Gaps = 6/381 (1%)
Query: 772 PDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSH 831
P AP P++ +V ++ +++WE P +DGG I+GY +E+K++ + W++ N E ++
Sbjct: 22536 PSAPTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNY 22595
Query: 832 EARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWR 891
+ ++EG+ Y+ R YA+NA G+S+ S AS+P M P P V DV+ +TVSL W
Sbjct: 22596 KVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQNPVDAPGRPEVTDVTRSTVSLIWS 22655
Query: 892 PPERVGAGGLDGYSVEYCP---EGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHN 948
P G + GY +E P G W+ + V L G FRV A N
Sbjct: 22656 APAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKN 22715
Query: 949 MAGP-GAPVTTTEPVTVQEILQRPRLQLPRHLR-QTIQKKVGEPVNLLIPFQGKPRPQVT 1006
AG +T PVT ++ P+ +L L + + G + L GKP P++
Sbjct: 22716 AAGVISKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIRAGSDLVLDAAVGGKPEPKII 22775
Query: 1007 WTKEGQPL-AGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDK 1065
WTK + L E+VS++ + I+ R SG Y +TV+ + +++++V+D
Sbjct: 22776 WTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLDS 22835
Query: 1066 PSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCV 1125
P P L V+ L W PQ+ G E+ Y V++ + + W V V
Sbjct: 22836 PGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLSYV 22895
Query: 1126 VPELIIGNGYYFRVFSQNMVG 1146
V LI N Y FRV + N G
Sbjct: 22896 VTRLIKNNEYIFRVRAVNKYG 22916
Score = 171 bits (432), Expect = 5e-42
Identities = 157/594 (26%), Positives = 238/594 (40%), Gaps = 72/594 (12%)
Query: 707 DSDEWVFDKKL-LCETEGRVRVETTKDRSIFTV-----EGAEKEDEGVYTVTVKNPVGED 760
D+D+WV K+ + +T RV+ T K + F V G K + + +K+P
Sbjct: 7620 DTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDP---- 7675
Query: 761 QVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMR 820
ID P P P + +VG+ S + W P +DGG I Y++E K + W+R
Sbjct: 7676 --------IDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVR 7727
Query: 821 LNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PIGPPSEPTHLA 877
+ + + H ++EG Y RV AVN G S PS S P + + PPS P L
Sbjct: 7728 VA-EGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLE 7786
Query: 878 VEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTG 937
V +++ T LKW PE+ G + Y VE W + + T V L G
Sbjct: 7787 VINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGW-QTVDTTVKDTKCTVTPLTEG 7845
Query: 938 ARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKV---------- 987
+ +FRV A N G + V ++ P + ++ V
Sbjct: 7846 SLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKND 7905
Query: 988 -GEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSP----TDTILFIRAARRVHSGT 1042
G P+ + + K R W K G+ AG + + R + T+ +RA G
Sbjct: 7906 GGRPIQRYV-IEKKERLGTRWVKAGKT-AGPDCNFRVTDVIEGTEVQFQVRAENEAGVGH 7963
Query: 1043 YQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTV 1102
I ++ED + PSPP DL VTDA ++A+ WKPP+ G + + GY V
Sbjct: 7964 PSEPTEILSIEDPTS-------PPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHV 8016
Query: 1103 QKADKKTMEWFTVLEH------YRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKE 1156
+ T +W V ++ VVP+ Y RV + N +G S E
Sbjct: 8017 EMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPD----KEYVLRVRAVNAIGVS-------E 8065
Query: 1157 PVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFK 1216
P I + +P +D T ++ VI G + R P P +SW K
Sbjct: 8066 PSEISENVVAKDPDCKPTIDLE-----THDII---VIEGEKLSIPVPFRAVPVPTVSWHK 8117
Query: 1217 NGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
+G ++ R M + LE+ K D GIY N G A ++V
Sbjct: 8118 DGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKV 8171
Score = 151 bits (381), Expect = 4e-36
Identities = 127/445 (28%), Positives = 198/445 (44%), Gaps = 36/445 (8%)
Query: 750 TVTVKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILE 809
T + +P+ V + + P AP P I+ V +DSC V W+PPA DGG I Y LE
Sbjct: 24498 TFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLE 24557
Query: 810 RKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPF----- 864
+++KK +W+ + + I+E + +IEG+ YE RV N G S S S+P
Sbjct: 24558 KREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSD 24617
Query: 865 MPIGPP---SEPTHLAVEDVSDTTVSLK-WRPPERVGAGGLDGYSVEYCPEGCSEWVAAL 920
+PI P E +L V S+ T+ K P+ + G E +G +
Sbjct: 24618 VPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQG--KEIIADGLKYRIQEF 24675
Query: 921 QGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLR 980
+G + +++ + +++VRA N G + E+ ++ LP+ L
Sbjct: 24676 KG--GYHQLIIASVTDDDATVYQVRATNQGG------SVSGTASLEVEVPAKIHLPKTLE 24727
Query: 981 --QTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGE----EVSIRNSPTDTILFIRA 1034
+ GE V++ IPF GKP P +TW K GQ L +V + S T +++F
Sbjct: 24728 GMGAVHALRGEVVSIKIPFSGKPDPVITWQK-GQDLIDNNGHYQVIVTRSFT-SLVFPNG 24785
Query: 1035 ARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGN 1094
R +G Y V + D+ T+ L V D P PP+ ++V+D +V L W P G
Sbjct: 24786 VERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGG 24845
Query: 1095 TELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATT 1154
+++ Y V+K W V R T V L Y FRV ++N G S
Sbjct: 24846 SKITNYIVEKCATTAERWLRV-GQARETRYTVINLFGKTSYQFRVIAENKFGLS------ 24898
Query: 1155 KEPVFIPRPGITYEPPNYKALDFSE 1179
+P P IT E +A+++ E
Sbjct: 24899 -KPSEPSEPTITKEDKT-RAMNYDE 24921
Score = 144 bits (364), Expect = 4e-34
Identities = 106/366 (28%), Positives = 162/366 (44%), Gaps = 48/366 (13%)
Query: 640 PRQEPPKI--------HLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGN 691
PR+ P I LD G ++ AG+ +++++P+ G P PTV W+K
Sbjct: 14743 PRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKK------ 14796
Query: 692 KAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTV 751
GD ++L +T+ RV ETT +I + + D G Y +
Sbjct: 14797 --------------GD--------QILKQTQ-RVNFETTATSTILNINECVRSDSGPYPL 14833
Query: 752 TVKNPVGEDQVNLTVKVIDVPDAPAAP-KISNVGEDSCTVQWEPPAYDGGQPILGYILER 810
T +N VGE +T++V D+P P P K V D T W+PP DGG PI Y++E
Sbjct: 14834 TARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEM 14893
Query: 811 KKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGM-----SRPSPASQPFM 865
++ S W+ L +I+ +++A R+ G+ Y+ RV A N G+ S A+ PF
Sbjct: 14894 RQTDSTTWVELATTVIRT-TYKATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFK 14952
Query: 866 PIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTE 925
GPP P V V+ ++++ W P G + GY VE W + L
Sbjct: 14953 VPGPPGTPQ---VTAVTKDSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVP 15009
Query: 926 HTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHL-RQTIQ 984
L G FRV A NMAG P +EP+ + + P +P ++ R T+
Sbjct: 15010 GNIFKSSGLTDGIAYEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHTVT 15069
Query: 985 KKVGEP 990
K +P
Sbjct: 15070 LKWAKP 15075
Score = 142 bits (357), Expect = 3e-33
Identities = 105/345 (30%), Positives = 153/345 (44%), Gaps = 43/345 (12%)
Query: 635 KIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNK-LRLDVPISGDPAPTVIWQKAITQGNKA 693
+I V R + LD G +PD + N RL +PI G PAP+V W+K
Sbjct: 13663 EITVVARDDVVAPDLDLKG-LPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKG------- 13714
Query: 694 PARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTV 753
ED T+ RV VE++ + V +K D G YT+T+
Sbjct: 13715 ---------EDP-------------LATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITL 13752
Query: 754 KNPVGEDQVNLTVKVIDVPDAPAAP-KISNVGEDSCTVQWEPPAYDGGQPILGYILERKK 812
KN G + +++KV+ P P P K V ++ T++W PP DGG I YILE++
Sbjct: 13753 KNVAGTKEGTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRD 13812
Query: 813 KKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGM-----SRPSPASQPF-MP 866
+ +W+ +Q+ + R+ EG+ Y RV A N G+ S P A PF +P
Sbjct: 13813 SVNNKWVTC-ASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVP 13871
Query: 867 IGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEH 926
PP P ++ DV +VSL W P++ G + GY +E+ W A +
Sbjct: 13872 DAPP--PPNIV--DVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRM 13927
Query: 927 TSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRP 971
V L G FRV A N+AG G P +EPV + + P
Sbjct: 13928 RDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPP 13972
Score = 140 bits (352), Expect = 1e-32
Identities = 120/428 (28%), Positives = 177/428 (41%), Gaps = 58/428 (13%)
Query: 375 VSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAY 434
V+ G EL+ D V+W G++++ S K + S G TLT+ L D
Sbjct: 5902 VTAGETATFDCELSYEDIPVEWYLKGKKLEPS-DKVVPRSEGKVHTLTLRDVKLEDAGEV 5960
Query: 435 QCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELT 494
Q K LFVKEPPV T+PLEDQ V G ECEVS E A+VKW K+G E+
Sbjct: 5961 QLTAKDFKTHANLFVKEPPVEFTKPLEDQTVEEGATAVLECEVSRENAKVKWFKNGTEIL 6020
Query: 495 REETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADL 554
+ + KY DG+ L+I++ ED Y + L V +E + + DL
Sbjct: 6021 KSK--KYEIVADGRVRKLVIHDCTPEDIKTYTCDAKDFKTSCNLNVVPPHVEFLRPLTDL 6078
Query: 555 MVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADY 614
V K+ A F+CE+S EN + W K+G E+ + + G V L I+ DEA+Y
Sbjct: 6079 QVREKEMARFECELSRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEY 6138
Query: 615 SFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPIS 674
S E S L +E + F I V + ++L +S
Sbjct: 6139 SC--EVRTARTSGMLTVLEEEAVFTKNLA--------------NIEVSETDTIKLVCEVS 6182
Query: 675 GDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRS 734
P VIW K GD + + ET GR + T +
Sbjct: 6183 -KPGAEVIWYK--------------------GDEE--------IIET-GRYEILTEGRKR 6212
Query: 735 IFTVEGAEKEDEGVYTVTVKNPVGEDQV---NLTVKVIDVP------DAPAAPKISNVGE 785
I ++ A ED G Y + + + +V L + I P + A + ++ +
Sbjct: 6213 ILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLEILEGEKAEFVCSISK 6272
Query: 786 DSCTVQWE 793
+S VQW+
Sbjct: 6273 ESFPVQWK 6280
Score = 137 bits (345), Expect = 7e-32
Identities = 127/511 (24%), Positives = 201/511 (39%), Gaps = 87/511 (17%)
Query: 643 EPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAP 702
+ P LD + D IVV AG L+ I G P P V+W K
Sbjct: 18398 DAPNASLD--PKYKDVIVVHAGETFVLEADIRGKPIPDVVWSK----------------- 18438
Query: 703 EDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQV 762
D K L ET R+ +++T ++ V+ + D G Y + + N G +
Sbjct: 18439 -----------DGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSI 18487
Query: 763 NLTVKVIDVPDAPAAP-KISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRL 821
+TVKV+D P P P K++ V + C + W PP DGG I YI+E+++ W ++
Sbjct: 18488 PITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLSWTQV 18547
Query: 822 NFDLIQELSHEARRMIEGVVYEMRVYAVNAIGM-----SRPSPASQPFMPIGPPSEPTHL 876
+ + +Q L+++ +++ G Y RV AVN G+ S P A P+ P GPPS P
Sbjct: 18548 STE-VQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACNPYKPPGPPSTP--- 18603
Query: 877 AVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPT 936
V ++ ++ + W P G ++GY +E + W + + V L
Sbjct: 18604 EVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLTDLRLRVTGLTE 18663
Query: 937 GARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIP 996
G FRV A N AG G P + + L P G P N +
Sbjct: 18664 GHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPP----------------GPPSNPKVT 18707
Query: 997 FQGKPRPQVTWTKE----GQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENM 1052
+ + W+K G P+ G V ++ + D + + VT EN
Sbjct: 18708 DTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENT 18767
Query: 1053 E--------------DKATLVLQVV--DKPSPPQ-----------DLRVTDAWGLNVALE 1085
E + ATL VV ++ PP+ LR + L V ++
Sbjct: 18768 EYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRASATLRLFVTIK 18827
Query: 1086 WKPPQDVGNTELWGYTVQKADKKTMEWFTVL 1116
+P +V + G +A + FT+L
Sbjct: 18828 GRPEPEVKWEKAEGILTDRAQIEVTSSFTML 18858
Score = 135 bits (340), Expect = 2e-31
Identities = 215/933 (23%), Positives = 349/933 (37%), Gaps = 118/933 (12%)
Query: 378 GHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCV 437
G + EL EV+WL+N + + G K+ S G L I D Y+ +
Sbjct: 6621 GADVVFLAELNKDKVEVQWLRNNMVV-VQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFI 6679
Query: 438 VGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSE-EGAQVKWLKDGVELTRE 496
++ +L + P + T +D +V VG+ + A+ +W K+ L+ +
Sbjct: 6680 AKDKEARAKLELAAAPKIKTAD-QDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTK 6738
Query: 497 ETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMV 556
++ I EA D G Y + AE + K ++V + +L V
Sbjct: 6739 T-----IDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEV 6793
Query: 557 GAKDQAVFKCEVSDENVRGVW---LKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEAD 613
E D V W L +G + ++ I R + D + E
Sbjct: 6794 ---------TETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAESCEFT 6844
Query: 614 YSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPI 673
+ + +G + F + V EP + D P V A +K DVP
Sbjct: 6845 VTGLQKG-----GVEYLFRVSARNRVGTGEP--VETDNP--------VEARSKY--DVP- 6886
Query: 674 SGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSD--EWVFDKK----LLCETEGRVRV 727
G P I T N+ + PE G ++ +V + + + +T VR
Sbjct: 6887 -GPPLNVTI-----TDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRA 6940
Query: 728 ETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLT---VKVIDVPDAPAAP---KIS 781
E VEG E + V +N +G + + VKV D + P+ P S
Sbjct: 6941 EDLSATVTDVVEGQEYS----FRVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSS 6996
Query: 782 NVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVV 841
+ + S ++WEPP DGG PILGYI+ER ++ W+R N L+ EL+++ + +G
Sbjct: 6997 DQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNK 7056
Query: 842 YEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGA-GG 900
Y RV A N G+S PS P EPT D+S L+ P +
Sbjct: 7057 YLYRVSAENKAGVSDPSEILGPLTADDAFVEPTM----DLSAFKDGLEVIVPNPITILVP 7112
Query: 901 LDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTE 960
GY P + W + L + +K L A L+ + G
Sbjct: 7113 STGY-----PRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENR 7167
Query: 961 PVTVQ-----EILQRPRLQLPRHLR-------------QTIQKKVGEPVNLLIPFQGKPR 1002
T+ ++ RP P+ L+ + G P+ + + +
Sbjct: 7168 VKTISGEIDVNVIARP--SAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYV-VEKREV 7224
Query: 1003 PQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIE--NMEDKATLVL 1060
+ TWTK + E ++ + + R G + E NM AT+
Sbjct: 7225 SRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATV-- 7282
Query: 1061 QVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYR 1120
P PP++++ D ++ L W PP++ G + + GY V++ + + +W E
Sbjct: 7283 -----PDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGEPVA 7337
Query: 1121 RTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEA 1180
T V L G Y +RV + N G S + T+E +A+D EA
Sbjct: 7338 ETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEE---------------IQAVDTQEA 7382
Query: 1181 PSF---TQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLT 1237
P + L +V AG L V G P+PKI+W K + L +D R + + T
Sbjct: 7383 PEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKST 7442
Query: 1238 LEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
+ I D G Y+ A N+ G A + V
Sbjct: 7443 VTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNV 7475
Score = 134 bits (338), Expect = 4e-31
Identities = 121/458 (26%), Positives = 200/458 (43%), Gaps = 38/458 (8%)
Query: 708 SDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVK 767
+D+WV K ++ TT ++TV G + E + + +N VG + + +
Sbjct: 24068 TDKWVRHNK--------TQITTT----MYTVTGLVPDAEYQFRIIAQNDVGLSETSPASE 24115
Query: 768 VI------DVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRL 821
+ D P P +I ++ +DS T+QWE P DGG+ ILGY +E ++ W +
Sbjct: 24116 PVVCKDPFDKPSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKS 24175
Query: 822 NFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDV 881
N + I++ ++E YE RV+A N G+SRP + E + E +
Sbjct: 24176 NKERIKDKQFTIGGLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPGIRKE-M 24234
Query: 882 SDTTVSLKWRPPERVGAGGLDGYSVEYCPEG-----CSEWVAALQGLTEHTSILVKDLPT 936
D T L G +++ G ++ + G T +++ ++
Sbjct: 24235 KDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQED 24294
Query: 937 GARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIP 996
++ A N G V T+ + +Q P+ L++ VG + L +
Sbjct: 24295 EG--VYTCIATNEVGE---VETSSKLLLQAT---PQFHPGYPLKEKYYGAVGSTLRLHVM 24346
Query: 997 FQGKPRPQVTWTKEGQPLA--GEEVSIRNSPTDTILFIR-AARRVHSGTYQVTVRIENME 1053
+ G+P P +TW GQ L E ++I N+ T L ++ R+ H+G Y+V +
Sbjct: 24347 YIGRPVPAMTWF-HGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGT 24405
Query: 1054 DKATLVLQVVDKPSPPQDLRVTDAWGLNVA-LEWKPPQDVGNTELWGYTVQKAD-KKTME 1111
A L +++ DKP P V +A N A + WKPP D G + + Y V+K + K+ E
Sbjct: 24406 VDAILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAE 24465
Query: 1112 WFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSD 1149
W V T C + L GYYFRV +QN G SD
Sbjct: 24466 WQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFGISD 24503
Score = 134 bits (337), Expect = 6e-31
Identities = 115/412 (27%), Positives = 167/412 (40%), Gaps = 57/412 (13%)
Query: 654 RIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVF 713
++ + V AG+ +RL+ + G P P V W K DA + T
Sbjct: 11901 KLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKD------------KDATDLTRSP----- 11943
Query: 714 DKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPD 773
RV+++T D S F++ A++ D G Y VT N G TV V+D P
Sbjct: 11944 ----------RVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPG 11993
Query: 774 APAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEA 833
KI +V D CTV W+PP DGG I YILE+ + K W + ++
Sbjct: 11994 PVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTP-GTTV 12052
Query: 834 RRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PIGPPSEPTHLAVEDVSDTTVSLKW 890
R+IEG Y RV A N IG P+ S+P + P P V VS +++ W
Sbjct: 12053 TRLIEGNEYIFRVRAENKIGTGPPT-ESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVW 12111
Query: 891 RPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMA 950
PPE G + GY +E + + WV + + V++L FRV+A N
Sbjct: 12112 NPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEI 12171
Query: 951 GPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKE 1010
G G P + PV ++ ++ P G P N + K + W K
Sbjct: 12172 GIGEPSLPSRPVVAKDPIEPP----------------GPPTNFRVVDTTKHSITLGWGKP 12215
Query: 1011 ----GQPLAGEEVSIR-----NSPTDTILFIRAARRVHSGTYQVTVRIENME 1053
G P+ G V +R SP + AA ++ + VT EN E
Sbjct: 12216 VYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQE 12267
Score = 132 bits (333), Expect = 2e-30
Identities = 101/340 (29%), Positives = 154/340 (45%), Gaps = 19/340 (5%)
Query: 649 LDCPGRIPDT-IVVVAGNKLRLDVPISGDPAPTVIWQKA--ITQGNKAPARPAPDAPEDT 705
+D P I T + V G+++ LD ISG P PT+ W K + + R AP
Sbjct: 8373 IDAPKVILRTSLEVKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRK 8432
Query: 706 GDSDEWVFDKKLLCETEGRVRVETTKD-RSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNL 764
G+ E ++ + R+ ++ +K S V + + D G+Y + V+N G +
Sbjct: 8433 GEVQE---EEPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPC 8489
Query: 765 TVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILER--KKKKSYRWMRLN 822
TV V+D P P ++ + S +WEPP DGG I+ Y LE+ K K W+ +
Sbjct: 8490 TVSVLDTPGPPINFVFEDIRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWIVVT 8549
Query: 823 FDLIQELSHEARRMIEGVVYEMRVYAVNAIG-----MSRPSPASQPFMPIGPPSEPTHLA 877
++ + ++IEG Y RV A N G +S+P A PF GPP P
Sbjct: 8550 -STLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKPLVAKDPF---GPPDAPDKPI 8605
Query: 878 VEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTG 937
VEDV+ ++ +KW P+ G+ L GY +E + W + L V L G
Sbjct: 8606 VEDVTSNSMLVKWNEPKDNGSPIL-GYWLEKREVNSTHWSRVNKSLLNALKANVDGLLEG 8664
Query: 938 ARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPR 977
+FRV A N AGPG ++P T + + P +PR
Sbjct: 8665 LTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIPR 8704
Score = 132 bits (331), Expect = 3e-30
Identities = 116/487 (23%), Positives = 193/487 (39%), Gaps = 56/487 (11%)
Query: 547 VYQSIADLMVGAKDQAVFKCEVSDENVRGV-WLKNGKELVPDSRIKVSHIGRVHKLTIDD 605
+ + + D+ + A C++ + + W + GKEL+ + K+S GR H LT+
Sbjct: 24230 IRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMT 24289
Query: 606 VTPADEADYSFVP--EGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVA 663
DE Y+ + E S+KL Q P+ H P + +
Sbjct: 24290 EEQEDEGVYTCIATNEVGEVETSSKLLL----------QATPQFHPGYP--LKEKYYGAV 24337
Query: 664 GNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEG 723
G+ LRL V G P P + W F + L +
Sbjct: 24338 GSTLRLHVMYIGRPVPAMTW-----------------------------FHGQKLLQNSE 24368
Query: 724 RVRVETTKDRSIFTVEGAEKEDE-GVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAP-KIS 781
+ +E T+ + ++ +++ G Y V + N G L V++ D PD P P I
Sbjct: 24369 NITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIE 24428
Query: 782 NVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVV 841
+ ++S + W+PPA DGG I Y++E+ + K +L I + + E
Sbjct: 24429 ALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAG 24488
Query: 842 YEMRVYAVNAIGMSRPSPAS------QPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPER 895
Y RV A N G+S P S PF G P +PT AV D+ V + W+PP
Sbjct: 24489 YYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAV--TKDSCV-VAWKPPAS 24545
Query: 896 VGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAP 955
G + Y +E + ++W++ T VK+L G FRV+ N+ G
Sbjct: 24546 DGGAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEW 24605
Query: 956 VTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLA 1015
+EP+T + + LR + + L+ G P+P V W ++G+ +
Sbjct: 24606 SEISEPITPKSDVPIQAPHFKEELR-NLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEII 24664
Query: 1016 GEEVSIR 1022
+ + R
Sbjct: 24665 ADGLKYR 24671
Score = 131 bits (329), Expect = 5e-30
Identities = 95/310 (30%), Positives = 133/310 (42%), Gaps = 39/310 (12%)
Query: 657 DTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKK 716
+T V+AG L++DVP G P P V W K D
Sbjct: 15850 NTFTVLAGEDLKVDVPFIGRPTPAVTWHK----------------------------DNV 15881
Query: 717 LLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPA 776
L +T RV E+T++ S+ T++ A +ED G Y V + N GE L V V+D P P
Sbjct: 15882 PLKQTT-RVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPPT 15940
Query: 777 AP-KISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARR 835
P K+ V DS T+ W PP YDGG I YI+E++ + W ++ + + +A R
Sbjct: 15941 GPVKMDEVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTWQIVSAT-VARTTIKACR 15999
Query: 836 MIEGVVYEMRVYAVNAIGMS-----RPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKW 890
+ G Y+ R+ A N G S P+ A PF GPP P V S ++ ++W
Sbjct: 16000 LKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPV---VTLSSRDSMEVQW 16056
Query: 891 RPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMA 950
P G + GY +E WV + T L G FRV A N+
Sbjct: 16057 NEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIV 16116
Query: 951 GPGAPVTTTE 960
G G P +E
Sbjct: 16117 GIGKPSKVSE 16126
Score = 130 bits (328), Expect = 6e-30
Identities = 94/317 (29%), Positives = 141/317 (44%), Gaps = 37/317 (11%)
Query: 643 EPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAP 702
+PP+I +D + DTIVV AG ++D I G P PT+ W K
Sbjct: 16234 DPPRISMD--PKYKDTIVVHAGESFKVDADIYGKPIPTIQWIK----------------- 16274
Query: 703 EDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQV 762
GD + R+ +++T + +V+ A + D G Y + KN GE V
Sbjct: 16275 ---GDQE---------LSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSV 16322
Query: 763 NLTVKVIDVPDAPAAP-KISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRL 821
+ VKV+D P P P IS V + CT+ W+PP DGG I+ YI+ER++ W +
Sbjct: 16323 TVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVV 16382
Query: 822 NFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGP---PSEPTHLAV 878
+ + +Q LS + +++EG Y R+ AVN G+ P S+P + P P P V
Sbjct: 16383 DAN-VQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPL-ESEPVVAKNPFVVPDAPKAPEV 16440
Query: 879 EDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGA 938
V+ ++ + W P G + GY +E + W + L + V L
Sbjct: 16441 TTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENH 16500
Query: 939 RLLFRVRAHNMAGPGAP 955
FRV A N AG P
Sbjct: 16501 DYEFRVSAENAAGLSEP 16517
Score = 128 bits (321), Expect = 4e-29
Identities = 99/421 (23%), Positives = 172/421 (40%), Gaps = 64/421 (15%)
Query: 644 PPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPE 703
PP+I L + + V AG + LD + G P PTV W+K
Sbjct: 12987 PPRIDLSVA--MKSLLTVKAGTNVCLDATVFGKPMPTVSWKK------------------ 13026
Query: 704 DTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVE--GAEKEDEGVYTVTVKNPVGEDQ 761
D LL EG ++ R++ T+E ++D G YT+T +N G
Sbjct: 13027 ----------DGTLLKPAEG---IKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKS 13073
Query: 762 VNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRL 821
+ +KV+D P PA+ KI+ + D + WEPP DGG I YI+++++ W ++
Sbjct: 13074 ATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNWAQV 13133
Query: 822 NFDLIQELSHEARRMIEGVVYEMRVYAVNAIGM-----SRPSPASQPFMPIGPPSEPTHL 876
+ + S ++IEG Y+ R+ A N G+ + P+ A P+ P G P
Sbjct: 13134 S-ATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPP--- 13189
Query: 877 AVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPT 936
+ +++ +++ W+PP G + GY +E W + ++ L
Sbjct: 13190 VISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQE 13249
Query: 937 GARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIP 996
G FRV A N AGPG P ++ ++ P G P +
Sbjct: 13250 GTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPP----------------GPPAFPKVY 13293
Query: 997 FQGKPRPQVTWTKE----GQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENM 1052
+ ++W K G P+ G V ++ + +D + + + ++VT +E+
Sbjct: 13294 DTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMEDT 13353
Query: 1053 E 1053
+
Sbjct: 13354 Q 13354
Score = 127 bits (320), Expect = 5e-29
Identities = 107/389 (27%), Positives = 163/389 (41%), Gaps = 50/389 (12%)
Query: 365 FQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTIS 424
F K LE V +G L E++ +A+VKW KNG EI + KY + G R L I
Sbjct: 5982 FTKPLEDQ-TVEEGATAVLECEVSRENAKVKWFKNGTEI-LKSKKYEIVADGRVRKLVIH 6039
Query: 425 QCSLADDAAYQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQV 484
C+ D Y C K S L V P V RPL D V + FECE+S E A+V
Sbjct: 6040 DCTPEDIKTYTCDAKDFKTSCNLNVVPPHVEFLRPLTDLQVREKEMARFECELSRENAKV 6099
Query: 485 KWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKK 544
KW KDG E+ + + KY G L+IN+ +L+D Y+ + L V E++
Sbjct: 6100 KWFKDGAEIKKGK--KYDIISKGAVRILVINKCLLDDEAEYSCEVRTARTSGMLTVLEEE 6157
Query: 545 LEVYQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTID 604
+++A++ V D CEVS +W K +E++ R ++ GR L I
Sbjct: 6158 AVFTKNLANIEVSETDTIKLVCEVSKPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQ 6217
Query: 605 DVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAG 664
+ D +Y+ + K+H E+ +F+ + P + ++ G
Sbjct: 6218 NAHLEDAGNYNCRLPSSRTDGKVKVH--ELAAEFISK--------------PQNLEILEG 6261
Query: 665 NKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGR 724
K IS + P V W++ D ++GD + + D G+
Sbjct: 6262 EKAEFVCSISKESFP-VQWKR-------------DDKTLESGDKYDVIAD--------GK 6299
Query: 725 VRVETTKDRSIFTVEGAEKEDEGVYTVTV 753
RV KD ++ +D G Y V V
Sbjct: 6300 KRVLVVKDATL--------QDMGTYVVMV 6320
Score = 127 bits (318), Expect = 9e-29
Identities = 91/356 (25%), Positives = 152/356 (42%), Gaps = 39/356 (10%)
Query: 643 EPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAP 702
E P+I +D R DTIVV AG RL+ + G P PT+ W +
Sbjct: 17316 ELPRISMDPKFR--DTIVVNAGETFRLEADVHGKPLPTIEWLRG---------------- 17357
Query: 703 EDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQV 762
DK++ E R ++ T +++ V+ A + D G Y + N G
Sbjct: 17358 -----------DKEI--EESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSF 17404
Query: 763 NLTVKVIDVPDAPAAP-KISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRL 821
+ VKV+D P P P +++ V + C++ W PP DGG I Y++E+++ W +
Sbjct: 17405 PVNVKVLDRPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISHYVVEKRETSRLAWTVV 17464
Query: 822 NFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM--PIGPPSEPTHLAVE 879
+++ S + +++EG Y R+ AVN G+ P ++ M P P P L V
Sbjct: 17465 ASEVVTN-SLKVTKLLEGNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVT 17523
Query: 880 DVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGAR 939
+++ ++++ W P+ G + GY VE W+ + + V L
Sbjct: 17524 NIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHE 17583
Query: 940 LLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKV----GEPV 991
FRV A N AG G P T + + +P H+ T + + G+P+
Sbjct: 17584 YEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPI 17639
Score = 127 bits (318), Expect = 9e-29
Identities = 97/336 (28%), Positives = 144/336 (42%), Gaps = 38/336 (11%)
Query: 640 PRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAP 699
P+ EP D G I AG+ +DVPISG PAP V W+
Sbjct: 22336 PQIEPTA---DLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWK--------------- 22377
Query: 700 DAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGE 759
++ L ET+ RV + TTKDR+ TV+ + + D G Y +T++N G
Sbjct: 22378 -------------LEEMRLKETD-RVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGV 22423
Query: 760 DQVNLTVKVIDVPDAPAAP-KISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRW 818
++TV VI P P ++S+V +SC + W P GG I YI+E+++ + W
Sbjct: 22424 KTFSVTVVVIGRPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAW 22483
Query: 819 MRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PIGPPSEPTH 875
+N ++ + + + + Y RV + N G+S+P S P + P PPS PT
Sbjct: 22484 QLVNSS-VKRTQIKVTHLTKYMEYSFRVSSENRFGVSKPLE-SAPIIAEHPFVPPSAPTR 22541
Query: 876 LAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLP 935
V VS +S++W P G + GY VE WV + + V L
Sbjct: 22542 PEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLV 22601
Query: 936 TGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRP 971
G FR A N AG + P+ Q + P
Sbjct: 22602 EGLEYQFRTYALNAAGVSKASEASRPIMAQNPVDAP 22637
Score = 124 bits (312), Expect = 4e-28
Identities = 103/421 (24%), Positives = 167/421 (39%), Gaps = 57/421 (13%)
Query: 643 EPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAP 702
E PKI +D + DT+++ AG RL+ +SG P PT+ W K
Sbjct: 15152 EAPKIKVDV--KFKDTVILKAGEAFRLEADVSGRPPPTMEWSK----------------- 15192
Query: 703 EDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQV 762
D K L E ++ ++ + + + + D G YT+T NP G +
Sbjct: 15193 -----------DGKEL-EGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGGFAKH 15240
Query: 763 NLTVKVIDVPDAPAAP-KISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRL 821
VKV+D P P P ++ V + C + W PP DGG I YI+++++ W +
Sbjct: 15241 IFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNV 15300
Query: 822 NFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PIGPPSEPTHLAV 878
+ +Q + ++++G Y RV AVN G+ P S+P + P GPP P + V
Sbjct: 15301 ASE-VQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPL-ESEPVLAVNPYGPPDPPKNPEV 15358
Query: 879 EDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGA 938
++ ++ + W P+ G + Y VE + W+ + V L G
Sbjct: 15359 TTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGH 15418
Query: 939 RLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQ 998
FR+ A N AG AP T+ + + +P G P N +
Sbjct: 15419 EYEFRIMAENAAGISAPSPTSPFYKACDTVFKP----------------GPPGNPRVLDT 15462
Query: 999 GKPRPQVTWTKE----GQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMED 1054
+ + W K G + G V I D + + + +Y +T EN E
Sbjct: 15463 SRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKATSYTITGLTENQEY 15522
Query: 1055 K 1055
K
Sbjct: 15523 K 15523
Score = 123 bits (309), Expect = 1e-27
Identities = 133/548 (24%), Positives = 211/548 (38%), Gaps = 60/548 (10%)
Query: 739 EGAEKEDEGVYTVTVKNPVGEDQVNLTVKVID------VPDAPAAPKISNVGEDSCTVQW 792
EG E E Y V +N G + T +I +P P+ PKI + G+ + T+ W
Sbjct: 19744 EGCEYE----YRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAW 19799
Query: 793 EPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAI 852
P +DGG PI GY +E KK W + + ++ + + G Y RV +VN +
Sbjct: 19800 VKPLFDGGAPITGYTVEYKKSDDTDW-KTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKV 19858
Query: 853 GMSRPSPASQPFMPIGPPSEPTHLAVEDVSDT-----------TVSLKWRPPERV--GAG 899
G S PS +S P + EP ++ T TV + RP V
Sbjct: 19859 GASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKP 19918
Query: 900 GLDGYSVEYCPEGCSEWVAALQGLTEHTS----ILVKDLPTGARLLFRVRAHNMAGPGAP 955
D + Y S ++ + S + ++++ + A L V+ + GP
Sbjct: 19919 DTDLRTRAYVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGPPTN 19978
Query: 956 VTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLA 1015
+T + +L +P + G PV + + + W
Sbjct: 19979 ITVQDVTKESAVLS---WDVP-------ENDGGAPVKNY-HIEKREASKKAWVSVTNNCN 20027
Query: 1016 GEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVT 1075
+ N I + R + G V + E E +++ +KPSPP+ L VT
Sbjct: 20028 RLSYKVTNLQEGAIYYFRVSGENEFG---VGIPAETKEG-----VKITEKPSPPEKLGVT 20079
Query: 1076 DAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGY 1135
+V+L W P+ G + + Y V+ +K W + TH VV L + Y
Sbjct: 20080 SISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQKNWVKCAVA-KSTHHVVSGLRENSEY 20138
Query: 1136 YFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAG 1195
+FRVF++N G SD PV I EPP +D PS T V AG
Sbjct: 20139 FFRVFAENQAGLSDPRELLL-PVLIKEQ---LEPPE---IDMKNFPSHTV-----YVRAG 20186
Query: 1196 YTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRA 1255
+ + G P PK++ ++G+ L RF LT+ +++ D G Y A
Sbjct: 20187 SNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITA 20246
Query: 1256 TNLQGEAR 1263
N G +
Sbjct: 20247 ANSSGTTK 20254
Score = 121 bits (304), Expect = 4e-27
Identities = 84/310 (27%), Positives = 131/310 (42%), Gaps = 39/310 (12%)
Query: 657 DTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKK 716
+T + AG L++++P+ G P P + W K D +
Sbjct: 18014 NTYSIQAGEDLKIEIPVIGRPRPNISWVK----------------------------DGE 18045
Query: 717 LLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPA 776
L +T RV VE T ++ ++ K+D G YTVT N G NL+V V++ P P
Sbjct: 18046 PLKQTT-RVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGPPV 18104
Query: 777 AP-KISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARR 835
P + V D + WEPPAY GG I YI+E++ + W ++ + + + +
Sbjct: 18105 GPVRFDEVSADFVVISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVSAT-VARTTIKITK 18163
Query: 836 MIEGVVYEMRVYAVNAIGMSRPSPASQ-----PFMPIGPPSEPTHLAVEDVSDTTVSLKW 890
+ G Y+ R++A N G S P + PF GPP P V +S + ++W
Sbjct: 18164 LKTGTEYQFRIFAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPF---VTSISKDQMLVQW 18220
Query: 891 RPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMA 950
P G + GY +E + WV + + T L G F+V A N+
Sbjct: 18221 HEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIV 18280
Query: 951 GPGAPVTTTE 960
G G P +E
Sbjct: 18281 GIGKPSKVSE 18290
Score = 121 bits (304), Expect = 4e-27
Identities = 89/349 (25%), Positives = 156/349 (44%), Gaps = 15/349 (4%)
Query: 738 VEGAEKEDEGVYTVTVKNPVG-----EDQVNLTVKV-IDVPDAPA-APKISNVGEDSCTV 790
V+G ++ E + V+ +N G + + +T K ++ P+ P+ P++ +V + S ++
Sbjct: 23984 VKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSL 24043
Query: 791 QWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVN 850
W P DGG + GY +ERK+ + +W+R N I + ++ Y+ R+ A N
Sbjct: 24044 SWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQFRIIAQN 24103
Query: 851 AIGMSRPSPASQPFM---PIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVE 907
+G+S SPAS+P + P PS+P L + +S +V+L+W PE G + GY VE
Sbjct: 24104 DVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVE 24163
Query: 908 YCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEI 967
Y G S W + + + + L FRV A N G P T ++++
Sbjct: 24164 YRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYEFRVFAENETGLSRPRRTA--MSIKTK 24221
Query: 968 LQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPL-AGEEVSIRNSPT 1026
L R + + K+GE L G+P P + W + G+ L + + +
Sbjct: 24222 LTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGR 24281
Query: 1027 DTILFIRAARRVHSGTYQ--VTVRIENMEDKATLVLQVVDKPSPPQDLR 1073
L + + G Y T + +E + L+LQ + P L+
Sbjct: 24282 THTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLK 24330
Score = 121 bits (303), Expect = 5e-27
Identities = 99/388 (25%), Positives = 160/388 (41%), Gaps = 45/388 (11%)
Query: 480 EGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELI 539
E Q KW+ E RE F + +G + + L ++ + +++
Sbjct: 24560 EKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSDVP 24619
Query: 540 VQEKKLEVYQSIADLMVGAKDQAVFKCEVSDENVRGV-WLKNGKELVPDS-RIKVSHI-G 596
+Q + + + +L V + A C+V+ V W + GKE++ D + ++ G
Sbjct: 24620 IQAPHFK--EELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKG 24677
Query: 597 RVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIP 656
H+L I VT D Y ++S +EV++ P KIHL
Sbjct: 24678 GYHQLIIASVTDDDATVYQVRATNQGGSVSGTAS-LEVEV-------PAKIHLPKTLEGM 24729
Query: 657 DTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKK 716
+ + G + + +P SG P P + WQK +
Sbjct: 24730 GAVHALRGEVVSIKIPFSGKPDPVITWQKG-----------------------------Q 24760
Query: 717 LLCETEGRVRVETTKD-RSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAP 775
L + G +V T+ S+ G E++D G Y V KN G DQ + + V DVPD P
Sbjct: 24761 DLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPP 24820
Query: 776 AAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARR 835
K+S+V DS + W PA DGG I YI+E+ + RW+R+ +E +
Sbjct: 24821 RGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVG--QARETRYTVIN 24878
Query: 836 MIEGVVYEMRVYAVNAIGMSRPSPASQP 863
+ Y+ RV A N G+S+PS S+P
Sbjct: 24879 LFGKTSYQFRVIAENKFGLSKPSEPSEP 24906
Score = 120 bits (301), Expect = 8e-27
Identities = 173/702 (24%), Positives = 278/702 (39%), Gaps = 103/702 (14%)
Query: 395 KWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCSTELFVKEPPV 454
KWLKNG EI+ S K + +L I D A Y V G + L+V+ +
Sbjct: 2954 KWLKNGVEIK-STDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHI 3012
Query: 455 LITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLII 514
+ ++D V+ +R FECEVSE V+W+KD EL + T + + +K+ H L+I
Sbjct: 3013 EFRKHIKDIKVLEKKRAMFECEVSEPDITVQWMKDDQEL--QITDRIKIQKEKYVHRLLI 3070
Query: 515 NEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDENVR 574
+ DAG Y + G + A+L V+ + + + ++ V K +AV + EV++++V
Sbjct: 3071 PSTRMSDAGKYTVVAGGNVSTAKLFVEGRDVRIRSIKKEVQVIEKQRAVVEFEVNEDDVD 3130
Query: 575 GVWLKNGKEL--VPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFM 632
W K+G E+ R K R+H++ I + +D +Y+FV +++
Sbjct: 3131 AHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVTL----- 3185
Query: 633 EVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNK 692
+V EPP++ + + V +G R ISG P P + W K
Sbjct: 3186 -----YVNAPEPPQVLQEL-----QPVTVQSGKPARFCAVISGRPQPKISWYK------- 3228
Query: 693 APARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVT 752
+E + C+ + ++ ++ +E A ED VYT
Sbjct: 3229 ----------------EEQLLSTGFKCKF-----LHDGQEYTLLLIE-AFPEDAAVYTCE 3266
Query: 753 VKNPVG--EDQVNLTVKVIDV--PDAPA---APKISNVGEDSCTVQWEPPAY----DGGQ 801
KN G +L+V+V +V PD P I +D+ T + +P + G
Sbjct: 3267 AKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTD 3326
Query: 802 PILGYILERKKKKSYRWMRLN--FDLIQELSHEARRMIEGVVYEMRVYAVNAIG-MSRPS 858
+ + + KK K R+ R+ D Q EA EG A NA+G +S +
Sbjct: 3327 LKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGT---YTFVASNAVGQVSSTA 3383
Query: 859 PASQPFMPIGPPSEPTHL-------AVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPE 911
S + S + AV D S T K E G S EY
Sbjct: 3384 NLSLEVQALDRQSSGKDVRESAKSQAVADSSFTKEESKISQKE---IKSFQGSSYEY--- 3437
Query: 912 GCSEWVAALQGLTE---HTSILVKD--LPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQE 966
V + +++ HT+ V+D L A L + ++ A +T E
Sbjct: 3438 ----EVQVFESVSQSSIHTAASVQDTQLCHTASLSQIAESTELSKECAKESTGE------ 3487
Query: 967 ILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPT 1026
P++ L HL Q + K G+ L + VTWT EG + E ++ S
Sbjct: 3488 ---APKIFL--HL-QDVTVKCGDTAQFLCVLKDDSFIDVTWTHEGAKIE-ESERLKQSQN 3540
Query: 1027 DTILFIRA--ARRVHSGTYQVTVRIENMEDKATLVLQVVDKP 1066
I F+ + V G Y V + E + VL V P
Sbjct: 3541 GNIQFLTICNVQLVDQGLYSCIVHNDCGERTTSAVLSVEGAP 3582
Score = 120 bits (301), Expect = 8e-27
Identities = 94/330 (28%), Positives = 139/330 (42%), Gaps = 42/330 (12%)
Query: 644 PPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPE 703
PPK LD D + + AG+ L LD + G P P +IW K
Sbjct: 22738 PPKAELDARLH-GDLVTIRAGSDLVLDAAVGGKPEPKIIWTKG----------------- 22779
Query: 704 DTGDSDEWVFDKKL-LCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQV 762
DK+L LCE +V ++ T R+ ++ ++ D G YT+TVKN G V
Sbjct: 22780 ----------DKELDLCE---KVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAV 22826
Query: 763 NLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLN 822
++ VKV+D P +S V ++ CT+ W P DGG I YI+ER++ W+ +
Sbjct: 22827 SVMVKVLDSPGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLNWVIVE 22886
Query: 823 FDLIQELSHEARRMIEGVVYEMRVYAVNAIG-----MSRPSPASQPFMPIGPPSEPTHLA 877
+ LS+ R+I+ Y RV AVN G S P A F PP P +
Sbjct: 22887 GE-CPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVG 22945
Query: 878 VEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEH-TSILVKDLPT 936
+ ++W PE G + Y V+ + W + + T + V L
Sbjct: 22946 ---TGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLME 23002
Query: 937 GARLLFRVRAHNMAGPGAPVTTTEPVTVQE 966
G FRV A N AG P + ++ +E
Sbjct: 23003 GCDYQFRVTAVNAAGNSEPSEASNFISCRE 23032
Score = 119 bits (298), Expect = 2e-26
Identities = 80/274 (29%), Positives = 134/274 (48%), Gaps = 6/274 (2%)
Query: 365 FQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTIS 424
F KL+ V K I L E++ DA VKW K+G+EI+ S + I ++ G KR L +
Sbjct: 5715 FTGKLQDYTGVEKDEVI-LQCEISKADAPVKWFKDGKEIKPSKNAVI-KADGKKRMLILK 5772
Query: 425 QCSLADDAAYQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQV 484
+ +D Y C G +K S +L +++ + + RPL VM + FE E+SE+
Sbjct: 5773 KALKSDIGQYTCDCGTDKTSGKLDIEDREIKLVRPLHSVEVMETETARFETEISEDDIHA 5832
Query: 485 KWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKK 544
W G L +T K++G+ H L+++ L+ G + ++ A L V+ +
Sbjct: 5833 NWKLKGEALL--QTPDCEIKEEGKIHSLVLHNCRLDQTGGVDFQAANVKSSAHLRVKPRV 5890
Query: 545 LEVYQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTID 604
+ + + + D+ V A + A F CE+S E++ W GK+L P ++ G+VH LT+
Sbjct: 5891 IGLLRPLKDVTVTAGETATFDCELSYEDIPVEWYLKGKKLEPSDKVVPRSEGKVHTLTLR 5950
Query: 605 DVTPADEADYSFVPEGFACNLSAKLHFMEVKIDF 638
DV D + + F + A L E ++F
Sbjct: 5951 DVKLEDAGEVQLTAKDFKTH--ANLFVKEPPVEF 5982
Score = 119 bits (297), Expect = 2e-26
Identities = 81/306 (26%), Positives = 131/306 (42%), Gaps = 39/306 (12%)
Query: 661 VVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCE 720
V G L+++VPISG P PT+ W K D L +
Sbjct: 16936 VQVGQDLKIEVPISGRPKPTITWTK----------------------------DGLPLKQ 16967
Query: 721 TEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAP-K 779
T R+ V + D + +++ K+D G Y +TV N VG+ ++ + +D PD P P K
Sbjct: 16968 TT-RINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVK 17026
Query: 780 ISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEG 839
+V +S T+ W PP Y GG I YI++++ + W ++ + + + ++ G
Sbjct: 17027 FDDVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSAT-VARTTLKVTKLKTG 17085
Query: 840 VVYEMRVYAVNAIGMS-----RPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPE 894
Y+ R++A N G S P A P+ GPP P A+ S ++ ++W P
Sbjct: 17086 TEYQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAI---SKDSMVIQWHEPV 17142
Query: 895 RVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGA 954
G + GY +E W + + T ++L G FRV A N+ G G
Sbjct: 17143 NNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGK 17202
Query: 955 PVTTTE 960
+E
Sbjct: 17203 ASKNSE 17208
Score = 118 bits (295), Expect = 4e-26
Identities = 86/275 (31%), Positives = 130/275 (47%), Gaps = 7/275 (2%)
Query: 365 FQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTIS 424
F KL V K +I L E++ D VKW K+G+EI S KY ++ G +R L I
Sbjct: 5360 FTVKLHDKTAVEKD-EITLKCEVSK-DVPVKWFKDGEEIVPS-PKYSIKADGLRRILKIK 5416
Query: 425 QCSLADDAAYQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQV 484
+ L D Y C G +K + V+ + + +PL V VG+ FE E+SE
Sbjct: 5417 KADLKDKGEYVCDCGTDKTKANVTVEARLIKVEKPLYGVEVFVGETAHFEIELSEPDVHG 5476
Query: 485 KWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKK 544
+W G LT + +DG++H LI++ L G + + ++ A L V+E
Sbjct: 5477 QWKLKGQPLTASPDCE--IIEDGKKHILILHNCQLGMTGEVSFQAANAKSAANLKVKELP 5534
Query: 545 LEVYQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTID 604
L ++D+ V KD+A F+CEVS E WLK +E+ D R ++ G H + I
Sbjct: 5535 LIFITPLSDVKVFEKDEAKFECEVSREPKTFRWLKGTQEITGDDRFELIKDGTKHSMVIK 5594
Query: 605 DVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFV 639
DEA Y F E + S KL +++ F+
Sbjct: 5595 SAAFEDEAKYMFEAED--KHTSGKLIIEGIRLKFL 5627
Score = 117 bits (294), Expect = 5e-26
Identities = 82/248 (33%), Positives = 119/248 (47%), Gaps = 8/248 (3%)
Query: 386 ELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCST 445
E++ + WLKNG EI+MS K+ G L I S D A Y V G ++ S
Sbjct: 2858 EVSHFNVPSMWLKNGVEIEMS-EKFKIVVQGKLHQLIIMNTSTEDSAEYTFVCGNDQVSA 2916
Query: 446 ELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKK 505
L V P++IT L+D + FE V+ EG KWLK+GVE+ + + R KK
Sbjct: 2917 TLTVT--PIMITSMLKDINAEEKDTITFEVTVNYEGISYKWLKNGVEIKSTDKCQMRTKK 2974
Query: 506 DGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFK 565
H L I DA Y + A L V+ + +E + I D+ V K +A+F+
Sbjct: 2975 --LTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIEFRKHIKDIKVLEKKRAMFE 3032
Query: 566 CEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNL 625
CEVS+ ++ W+K+ +EL RIK+ VH+L I +D Y+ V G N+
Sbjct: 3033 CEVSEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVAGG---NV 3089
Query: 626 SAKLHFME 633
S F+E
Sbjct: 3090 STAKLFVE 3097
Score = 117 bits (294), Expect = 5e-26
Identities = 76/266 (28%), Positives = 117/266 (43%), Gaps = 7/266 (2%)
Query: 370 EPAY--QVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCS 427
+P Y +V G +EL++ D +W GQ + S I E G K L + C
Sbjct: 5450 KPLYGVEVFVGETAHFEIELSEPDVHGQWKLKGQPLTASPDCEIIED-GKKHILILHNCQ 5508
Query: 428 LADDAAYQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWL 487
L K + L VKE P++ PL D V +FECEVS E +WL
Sbjct: 5509 LGMTGEVSFQAANAKSAANLKVKELPLIFITPLSDVKVFEKDEAKFECEVSREPKTFRWL 5568
Query: 488 KDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEV 547
K E+T ++ F+ KDG +H ++I A ED Y +LI++ +L+
Sbjct: 5569 KGTQEITGDDRFE--LIKDGTKHSMVIKSAAFEDEAKYMFEAEDKHTSGKLIIEGIRLKF 5626
Query: 548 YQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVT 607
+ D+ K+ AVF E+S +N+R W KN + L + + G+ H +T D++
Sbjct: 5627 LTPLKDVTAKEKESAVFTVELSHDNIRVKWFKNDQRLHTTRSVSMQDEGKTHSITFKDLS 5686
Query: 608 PADEADYSFVPEGFACNLSAKLHFME 633
D + E + AKL +E
Sbjct: 5687 IDDTSQIRV--EAMGMSSEAKLTVLE 5710
Score = 115 bits (289), Expect = 2e-25
Identities = 84/310 (27%), Positives = 138/310 (44%), Gaps = 12/310 (3%)
Query: 360 KKSTAFQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKR 419
K+ F ++L+ K E ++ +VKW K+G E+ G KY S
Sbjct: 2125 KQLITFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVH-EGDKYRMHSDRKVH 2183
Query: 420 TLTISQCSLADDAAYQCVVGGE---KCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECE 476
L+I +D Y CV+ + K + +L V+ V + L+D V E EC
Sbjct: 2184 FLSILTIDTSDAEDYSCVLVEDENVKTTAKLIVEGAVVEFVKELQDIEVPESYSGELECI 2243
Query: 477 VSEEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALA 536
VS E + KW + VEL + KY R +L + + ED G Y+ G +
Sbjct: 2244 VSPENIEGKWYHNDVEL--KSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGKKTTC 2301
Query: 537 ELIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIG 596
+L ++ + + + Q ++D V D + +VS E+V GVW+K+G+E+ P R+ +
Sbjct: 2302 KLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHIVIDK 2361
Query: 597 RVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQ-----EPPKIHLDC 651
+ H L I+D+T D +YSF + S ++ V + P + E K L+C
Sbjct: 2362 QSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVDV-ITPLKDVNVIEGTKAVLEC 2420
Query: 652 PGRIPDTIVV 661
+PD V
Sbjct: 2421 KVSVPDVTSV 2430
Score = 114 bits (285), Expect = 6e-25
Identities = 99/408 (24%), Positives = 161/408 (39%), Gaps = 59/408 (14%)
Query: 649 LDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDS 708
+D P + + AG ++L ISG PAPT+ W K
Sbjct: 20567 IDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKD---------------------- 20604
Query: 709 DEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKV 768
DK+L +T V VE T D + ++ A++ + G Y + ++N +G + V++
Sbjct: 20605 -----DKEL--QTNALVCVENTTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQI 20657
Query: 769 IDVPDAPAAP-KISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQ 827
+D P P P + V + T+ W PPA DGG I YI+E+++ W ++ + ++
Sbjct: 20658 LDKPGPPGGPIEFKTVTAEKITLLWRPPADDGGAKITHYIVEKRETSRVVWSMVS-EHLE 20716
Query: 828 ELSHEARRMIEGVVYEMRVYAVNAIGMSRPSP-----ASQPFMPIGPPSEPTHLAVEDVS 882
E ++I+G Y RV AVN G+ P A F+ GPP P V ++
Sbjct: 20717 ECIITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIP---EVTKIT 20773
Query: 883 DTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLF 942
++++ W P G + GY +E + W L+ T V L + +
Sbjct: 20774 KNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQY 20833
Query: 943 RVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPR 1002
RV A N AG G +E + + P G P + I K
Sbjct: 20834 RVCAVNAAGQGPFSEPSEFYKAADPIDPP----------------GPPAKIRIADSTKSS 20877
Query: 1003 PQVTWTKE----GQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVT 1046
+ W+K G + G V IR + + V + Y V+
Sbjct: 20878 ITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVS 20925
Score = 112 bits (281), Expect = 2e-24
Identities = 106/428 (24%), Positives = 172/428 (40%), Gaps = 58/428 (13%)
Query: 867 IGPPSEPTH-LAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTE 925
IG P+ P L +D+ +V + WRPP G + GY +E + W +
Sbjct: 23920 IGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYT-IDSRVR 23978
Query: 926 HTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQK 985
TS++VK L FRV A N G P+ + EPVT + L P + P + + +
Sbjct: 23979 GTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPP--EPPSNPPEVLDV 24036
Query: 986 KVGEPVNLLIPFQGKPRPQVTWTKE----GQPLAGEEVSIRNSPTDTILFIRAAR-RVHS 1040
K ++W++ G + G + + + TD ++R + ++ +
Sbjct: 24037 T-------------KSSVSLSWSRPKDDGGSRVTGYYIERKETSTDK--WVRHNKTQITT 24081
Query: 1041 GTYQVTVRIENMEDKATLVLQ-------------------VVDKPSPPQDLRVTDAWGLN 1081
Y VT + + E + ++ Q DKPS P +L + +
Sbjct: 24082 TMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKDS 24141
Query: 1082 VALEWKPPQDVGNTELWGYTVQKADKKTMEWF-TVLEHYRRTHCVVPELIIGNGYYFRVF 1140
V L+W+ P+ G E+ GY V+ W + E + + L+ Y FRVF
Sbjct: 24142 VTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYEFRVF 24201
Query: 1141 SQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAML 1200
++N G S RP T K L EAP + + + + G A L
Sbjct: 24202 AENETGLS-------------RPRRTAMSIKTK-LTSGEAPGIRKEMKDVTTKLGEAAQL 24247
Query: 1201 CCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQG 1260
C + G P P I W++ G +L + +++M S TL + D G+Y C ATN G
Sbjct: 24248 SCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVG 24307
Query: 1261 EARCECRL 1268
E +L
Sbjct: 24308 EVETSSKL 24315
Score = 112 bits (280), Expect = 2e-24
Identities = 127/527 (24%), Positives = 203/527 (38%), Gaps = 79/527 (14%)
Query: 769 IDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFD-LIQ 827
I P P PK+ + ++ + W P DGG PILGY++E +K + +W R+N D LI+
Sbjct: 11496 IKPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKDELIR 11555
Query: 828 ELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMP---IGPPSEPTHLAVEDVSDT 884
+ + +IEG Y R+ A N +G P ++ + + PP + DV
Sbjct: 11556 QCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRDVITV 11615
Query: 885 TVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSI-LVKDLPTGARLLFR 943
V R RV PE W + L + L++DLP R+ +
Sbjct: 11616 RVGQTIRILARVKGR----------PEPDITWTKEGKVLVREKRVDLIQDLP---RVELQ 11662
Query: 944 VRAHNMAGPGAPVTTTEPVT-------VQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIP 996
++ A G + + + + + +L RP G NL +
Sbjct: 11663 IKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRP----------------GPCQNLKVT 11706
Query: 997 FQGKPRPQVTWTKE----GQPLAGEEVSIRNS--------PTDTILFIRAARRVHSGTYQ 1044
K ++W G + V R +D + A + + Y
Sbjct: 11707 NVTKENCTISWENPLDNGGSEITNFIVEYRKPNQKGWSIVASDVTKRLIKANLLANNEYY 11766
Query: 1045 VTVRIEN-------MEDKAT-LVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTE 1096
V EN +E K L + +D+P P++L + D V L+W+ P G +
Sbjct: 11767 FRVCAENKVGVGPTIETKTPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSP 11826
Query: 1097 LWGYTVQKADKKTMEWFTVLE-HYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTK 1155
Y V++ K + +W V + + TH +V + Y FRV ++N G SD T +
Sbjct: 11827 NLSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVENQIYEFRVQTKNEGGESDWVKTEE 11886
Query: 1156 EPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWF 1215
+ E LD + T V AG T L VRG P P+++W
Sbjct: 11887 V--------VVKEDLQKPVLDLKLSGVLT-------VKAGDTIRLEAGVRGKPFPEVAWT 11931
Query: 1216 --KNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQG 1260
K+ DL R ++ ++ + K DGG YV ATN G
Sbjct: 11932 KDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAG 11978
Score = 110 bits (274), Expect = 1e-23
Identities = 148/625 (23%), Positives = 238/625 (38%), Gaps = 79/625 (12%)
Query: 684 QKAITQGNKAPARPAPDAPEDTGDS-DEWVFDKKLLCETEGRVRVETTKD--------RS 734
Q +T+ K A + P D G ++ +K+ ET + TKD R
Sbjct: 10712 QPIVTEVTKDSALVTWNKPHDGGKPITNYILEKR---ETMSKRWARVTKDPIHPYTKFRV 10768
Query: 735 IFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDV------PDAPAAPKISNVGEDSC 788
+EG + E + V+ +N +G + K + P P P+ + +S
Sbjct: 10769 PDLLEGCQYE----FRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSV 10824
Query: 789 TVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNF--DLIQELSHEARRMIEGVVYEMRV 846
+ W+PP +DGG ILGYI+E +K W R N + E ++ + +G Y+ RV
Sbjct: 10825 DLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRV 10884
Query: 847 YAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSV 906
AVNA G S P+ +P + + EP L ++ +K R+ A +
Sbjct: 10885 LAVNAAGESDPAHVPEPVL-VKDRLEPPELILDANMAREQHIKVGDTLRLSA------II 10937
Query: 907 EYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQE 966
+ P W + T + P G++L R AH G + +T P +
Sbjct: 10938 KGVPFPKVTW--KKEDRDAPTKARIDVTPVGSKLEIRNAAHEDGGIYS-LTVENPAGSKT 10994
Query: 967 ILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKE----GQPLAGEEVSIR 1022
+ ++ + K G P +L + K +TW + G + V R
Sbjct: 10995 V----------SVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERR 11044
Query: 1023 N------SPTDTILFIRA--ARRVHSGT-YQVTVRIENMEDKATLV--------LQVVDK 1065
+ SP ++ A+ ++ G Y V EN + V L +
Sbjct: 11045 DVASAQWSPLSATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHP 11104
Query: 1066 PSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCV 1125
P PP+DL D V+L W P G + + GY V+ ++ T +W + CV
Sbjct: 11105 PGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIK-FKTVTNLECV 11163
Query: 1126 VPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQ 1185
V L G Y FRV ++N+VG T P+ + PP+ + LD +
Sbjct: 11164 VTGLQQGKTYRFRVKAENIVGLG--LPDTTIPIECQEKLV---PPSVE-LDV----KLIE 11213
Query: 1186 PLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCP 1245
LV V AG T +RG P P W +G ++ D + + + L I+
Sbjct: 11214 GLV---VKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLR 11270
Query: 1246 FDGGIYVCRATNLQGEARCECRLEV 1270
D G Y +N G L V
Sbjct: 11271 RDTGEYQITVSNAAGSKTVAVHLTV 11295
Score = 109 bits (272), Expect = 2e-23
Identities = 185/803 (23%), Positives = 284/803 (35%), Gaps = 153/803 (19%)
Query: 542 EKKLEVYQSIADLMVGAKDQAVFK-CEVSDENVRGVWLKN--GKELVPDSRIKVSHIGRV 598
+K+L++ + ++ G + AV K C+ SD + +KN G + V + G
Sbjct: 22780 DKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLDSPGPC 22839
Query: 599 HKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIH-LDCPGRIPD 657
KLT+ VT A +L + E+ V R+E +++ + G P
Sbjct: 22840 GKLTVSRVTQEKCT--------LAWSLPQEDGGAEITHYIVERRETSRLNWVIVEGECPT 22891
Query: 658 TIVVV--------------AGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPE 703
VV A NK VP+ +P I N P PE
Sbjct: 22892 LSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEP---------IVARNSFTIPSPPGIPE 22942
Query: 704 DTGDSDEWVFDKKLLCETEGRVRVET----------------TKDRSIFT--------VE 739
+ G E + + E++G + KD ++ +E
Sbjct: 22943 EVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLME 23002
Query: 740 GAEKEDEGVYTVTVKNPVGEDQVNLTVKVID------VPDAPAAPKISNVGEDSCTVQWE 793
G + + + VT N G + + I P P+AP++ + + S ++ W
Sbjct: 23003 GCDYQ----FRVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWT 23058
Query: 794 PPAYDGGQPILGYILERKKKKSYRWMRLNFDL-IQELSHEARRMIEGVVYEMRVYAVNAI 852
P YDGG I+GY+LE ++K + +W R++ + I+ + G Y RV AVN
Sbjct: 23059 KPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVK 23118
Query: 853 GMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTT-----------VSLKWRPPERVGAGGL 901
GMS S + P+ P +D+ T VS+ RPP
Sbjct: 23119 GMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIRAGASLRLMVSVSGRPPP------- 23171
Query: 902 DGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARL-LFRVRAHNMAGPGAPVTTTE 960
+ + +G A+ TE S+L+ D + + A N +G + +
Sbjct: 23172 ---VITWSKQGIDLASRAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVK 23228
Query: 961 PVTVQEILQRPRLQLPRHLRQTIQKKV-----GEPVNLLIPFQGKPRPQVTWTKEGQPLA 1015
+++ TI ++ G PVN I + +E A
Sbjct: 23229 VYDTPGPCPSVKVKEVSRDSVTITWEIPTIDGGAPVNNYIVEK----------REAAMRA 23278
Query: 1016 GEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENM--------EDKATLVLQVVDKPS 1067
+ V+ + S T R + V Y V EN+ A LV +V P
Sbjct: 23279 FKTVTTKCSKT----LYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSEV---PL 23331
Query: 1068 PPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWF-------TVLEHYR 1120
P L V D V L W+ P G + L GY ++ T W TVLEH
Sbjct: 23332 VPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEH-- 23389
Query: 1121 RTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEA 1180
V L G Y FR+ +QN G S+ PR +T D
Sbjct: 23390 ----TVTSLNEGEQYLFRIRAQNEKGVSE-----------PRETVTA----VTVQDLRVL 23430
Query: 1181 PSF---TQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLT 1237
P+ T P V AG L + G P P SWF G L E R + + V
Sbjct: 23431 PTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAK 23490
Query: 1238 LEIRKPCPFDGGIYVCRATNLQG 1260
L IR+ D G Y N+ G
Sbjct: 23491 LTIRETTIRDTGEYTLELKNVTG 23513
Score = 108 bits (270), Expect = 3e-23
Identities = 83/275 (30%), Positives = 134/275 (48%), Gaps = 11/275 (4%)
Query: 374 QVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAA 433
++ +G K ++ V+W ++ + ++ SG KY + G KR L + +L D
Sbjct: 6257 EILEGEKAEFVCSISKESFPVQWKRDDKTLE-SGDKYDVIADGKKRVLVVKDATLQDMGT 6315
Query: 434 YQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVEL 493
Y +VG + + L V E + I PL+D V Q V F CEV+ EGA+ KW ++ E
Sbjct: 6316 YVVMVGAARAAAHLTVIEK-LRIVVPLKDTRVKEQQEVVFNCEVNTEGAKAKWFRN--EE 6372
Query: 494 TREETFKYRFKKDGQRHHLIINEAMLEDAGHY--ALCTSGGQ---ALAELIVQEKKLEVY 548
++ KY + + L I +A L+D +Y +L G+ + A LIV+E+ L +
Sbjct: 6373 AIFDSSKYIILQKDLVYTLRIRDAHLDDQANYNVSLTNHRGENVKSAANLIVEEEDLRIV 6432
Query: 549 QSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTP 608
+ + D+ K F C+V+ NV W KNG+E+ D+R+ H LTI D
Sbjct: 6433 EPLKDIETMEKKSVTFWCKVNRLNVTLKWTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGF 6492
Query: 609 ADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQE 643
DE +Y V G ++ A+L +E +FV E
Sbjct: 6493 PDEGEY-IVTAGQDKSV-AELLIIEAPTEFVEHLE 6525
Score = 107 bits (268), Expect = 6e-23
Identities = 72/235 (30%), Positives = 117/235 (49%), Gaps = 8/235 (3%)
Query: 384 TVELADHDAE-VKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEK 442
TVEL + + V+W+KNG ++ S KY G +L I C++ D++ Y +G
Sbjct: 2681 TVELTHPNVKGVQWIKNGVVLE-SNEKYAISVKGTIYSLRIKNCAIVDESVYGFRLGRLG 2739
Query: 443 CSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYR 502
S L V+ V I + +D + V FE VS + VKW VE+ + K+R
Sbjct: 2740 ASARLHVET--VKIIKKPKDVTALENATVAFEVSVSHDTVPVKWFHKSVEIKPSD--KHR 2795
Query: 503 FKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQA 562
+ + H L++ DAG Y + A+L V+ L + +++ ++ V A
Sbjct: 2796 LVSERKVHKLMLQNISPSDAGEYTAVVGQLECKAKLFVET--LHITKTMKNIEVPETKTA 2853
Query: 563 VFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFV 617
F+CEVS NV +WLKNG E+ + K+ G++H+L I + + D A+Y+FV
Sbjct: 2854 SFECEVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFV 2908
Score = 107 bits (268), Expect = 6e-23
Identities = 98/412 (23%), Positives = 161/412 (39%), Gaps = 41/412 (9%)
Query: 868 GPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHT 927
GPP+ P ++ DV+ +++ W+PP+ G + Y VE W G ++ T
Sbjct: 11300 GPPTGPINIL--DVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSK-T 11356
Query: 928 SILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKV 987
+ + L G +FRVRA N G G P+ +T V + + P + + +
Sbjct: 11357 KLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVA------KHKFSPPSPPGKPVVTDI 11410
Query: 988 GE---PVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQ 1044
E V+ +P P + E + + G+ V + +P + F R TY+
Sbjct: 11411 TENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVNKTPIADLKF-RVTGLYEGNTYE 11469
Query: 1045 VTVRIENM--------EDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTE 1096
V EN+ + + P PP + ++ D L W P G +
Sbjct: 11470 FRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGGSP 11529
Query: 1097 LWGYTVQKADKKTMEWFTVLEHYRRTHCV--VPELIIGNGYYFRVFSQNMVGFSDRAATT 1154
+ GY V+ T +W + + C VP LI GN Y FR+ + N+VG +
Sbjct: 11530 ILGYVVECQKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELA 11589
Query: 1155 KEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIA---GYTAMLCCAVRGSPKPK 1211
+ + A D P + R VI G T + V+G P+P
Sbjct: 11590 ESVI---------------AKDILHPPEVELDVTCRDVITVRVGQTIRILARVKGRPEPD 11634
Query: 1212 ISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEAR 1263
I+W K G L + R + + L+I++ D G Y+ A N G A+
Sbjct: 11635 ITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSGHAQ 11686
Score = 106 bits (265), Expect = 1e-22
Identities = 124/571 (21%), Positives = 216/571 (37%), Gaps = 99/571 (17%)
Query: 736 FTVEGAEKEDEGVYTVTVKNPVGEDQVNLT---VKVIDV---PDAPAAPKISNVGEDSCT 789
+ V G + E + + +N G + T K D P P P++ + S +
Sbjct: 15409 YKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSIS 15468
Query: 790 VQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDL-IQELSHEARRMIEGVVYEMRVYA 848
+ W P YDGG I GY++E + W + ++ S+ + E Y++R+YA
Sbjct: 15469 IAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYA 15528
Query: 849 VNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTT----------------VSLKWRP 892
+N+ G+ P+ +P P +E L E D V +K RP
Sbjct: 15529 MNSEGLGEPA-----LVPGTPKAEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRP 15583
Query: 893 PERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGP 952
V G S++ A+++ + +T ++V ++ + + N +G
Sbjct: 15584 APEVKWARDHGESLDK---------ASIESTSSYTLLIVGNVNRFDSGKYILTVENSSGS 15634
Query: 953 GAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQ 1012
+ +L P G P +L + K +TW
Sbjct: 15635 KSAFVNVR------VLDTP----------------GPPQDLKVKEVTKTSVTLTWDP--- 15669
Query: 1013 PLAGEEVSIRNSPTDTILFIRAA-RRVHSGTYQVTVRIENMEDKATLVLQVV-------- 1063
PL I+N + R A V + ++ + +++ +++ + +V+
Sbjct: 15670 PLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLAENEYGIG 15729
Query: 1064 ------------DKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTME 1111
++P PP + + D +V+L W+ P+ G + + GY V+ K + +
Sbjct: 15730 LPAETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDK 15789
Query: 1112 WFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPN 1171
W T + T + LI G Y FRV +QN G SD P + P I
Sbjct: 15790 WATCAT-VKVTEATITGLIQGEEYSFRVSAQNEKGISD-------PRQLSVPVI------ 15835
Query: 1172 YKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFS 1231
A D P+F +V+AG + G P P ++W K+ + L + R S
Sbjct: 15836 --AKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAES 15893
Query: 1232 KQGVLTLEIRKPCPFDGGIYVCRATNLQGEA 1262
+ L I+ C D G YV + TN GEA
Sbjct: 15894 TENNSLLTIKDACREDVGHYVVKLTNSAGEA 15924
Score = 105 bits (263), Expect = 2e-22
Identities = 87/330 (26%), Positives = 141/330 (42%), Gaps = 40/330 (12%)
Query: 644 PPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPE 703
PP I L R DTI V AG + + ++G P P + W K N+ DA +
Sbjct: 9089 PPTIKLRLSVR-GDTIKVKAGEPVHIPADVTGLPMPKIEWSK-----NETVIEKPTDALQ 9142
Query: 704 DTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVN 763
T + V ++ ++ ++ A +ED+G YTVT N +G N
Sbjct: 9143 ITKEE------------------VSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRN 9184
Query: 764 LTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERK--KKKSYRWMRL 821
+ V+V D P P ++++ +SC + W+ P +GG I Y+++++ +K W +
Sbjct: 9185 VHVEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEV 9244
Query: 822 NFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQ-----PFMPIGPPSEPTHL 876
+ E + ++I YE RV AVN G+S + + P+ GPP +P L
Sbjct: 9245 TNTAV-EKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVL 9303
Query: 877 AVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSIL-----V 931
A + ++ + W PP G + GY +E EG W + + V
Sbjct: 9304 A---RTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVGLKGVEFNV 9360
Query: 932 KDLPTGARLLFRVRAHNMAGPGAPVTTTEP 961
L G + FR A N AG G P ++P
Sbjct: 9361 PRLLEGVKYQFRAMAINAAGIGPPSEPSDP 9390
Score = 105 bits (263), Expect = 2e-22
Identities = 85/322 (26%), Positives = 132/322 (40%), Gaps = 40/322 (12%)
Query: 657 DTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKK 716
D +++ +G LR+ + G P P V W K G
Sbjct: 21661 DGLIIKSGESLRIKALVQGRPVPRVTWFK---DG-------------------------- 21691
Query: 717 LLCETEGRVRVETTK---DRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPD 773
E E R+ +E T S+F V A ++ GVYTV KN G + + VKV D P
Sbjct: 21692 --VEIEKRMNMEITDVLGSTSLF-VRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPG 21748
Query: 774 APAAP-KISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHE 832
P + +N+ + T+ W+ P DG PI YI+E+++ W + D + S+
Sbjct: 21749 KVVGPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIE-DKCEAQSYT 21807
Query: 833 ARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPI--GPPSEPTHLAVEDVSDTTVSLKW 890
A ++I G Y+ RV AVN G+ RP + I P P +++ +++L W
Sbjct: 21808 AIKLINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTW 21867
Query: 891 RPPERVGAGGLDGYSVEYCPEGCSEWVAAL-QGLTEHTSILVKDLPTGARLLFRVRAHNM 949
PE G + Y +E + + WV + + T V L G F V A N
Sbjct: 21868 ARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVMAENA 21927
Query: 950 AGPGAPVTTTEPVTVQEILQRP 971
AG G + + +E + P
Sbjct: 21928 AGVGPASGISRLIKCREPVNPP 21949
Score = 105 bits (261), Expect = 4e-22
Identities = 130/548 (23%), Positives = 207/548 (37%), Gaps = 57/548 (10%)
Query: 738 VEGAEKEDEGVYTVTVKNPVGEDQ---VNLTVKVIDV---PDAPAAPKISNVGEDSCTVQ 791
V G ++ E + V+ +N G + + K D P P I + ++S T+
Sbjct: 17575 VTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLA 17634
Query: 792 WEPPAYDGGQPILGYILERKKKKSYRWMRLNFDL-IQELSHEARRMIEGVVYEMRVYAVN 850
W P YDGG ILGY++E K W + ++ E ++ E Y++RV A+N
Sbjct: 17635 WGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALN 17694
Query: 851 AIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCP 910
+G+ + P P + + + R V AGG + +
Sbjct: 17695 KVGLGEATSVPGTVKPEDKLEAP---------ELDLDSELRKGIVVRAGGSARIHIPFKG 17745
Query: 911 EGCSE--WVAALQGLTE---------HTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTT 959
E W T+ +T + + + + ++ N +G + T
Sbjct: 17746 RPTPEITWSREEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVT- 17804
Query: 960 EPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEV 1019
V V + P+ + +R+ V EP +I K + V +E A V
Sbjct: 17805 --VKVLDTPGPPQNLAVKEVRKDSAFLVWEPP--IIDGGAKVKNYVIDKRESTRKAYANV 17860
Query: 1020 SIRNSPTDTILFIRAARRVHSGTYQVTVRIEN-----MEDKATLVLQVVDKPSPPQDLRV 1074
S + S T + Y V EN + + ++ + PSPP + +
Sbjct: 17861 SSKCSKTS----FKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEPPSPPGKVTL 17916
Query: 1075 TDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNG 1134
TD + +L W+ P+ G + + GY V+ K T +W V E + + VV L G
Sbjct: 17917 TDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAES-KVCNAVVTGLSSGQE 17975
Query: 1135 YYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIA 1194
Y FRV + N G SD P + P I A D + PS P S+ A
Sbjct: 17976 YQFRVKAYNEKGKSD-------PRVLGVPVI--------AKDLTIQPSLKLPFNTYSIQA 18020
Query: 1195 GYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCR 1254
G + V G P+P ISW K+G L + R + L I++ D G Y
Sbjct: 18021 GEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVT 18080
Query: 1255 ATNLQGEA 1262
ATN G A
Sbjct: 18081 ATNSAGTA 18088
Score = 104 bits (260), Expect = 5e-22
Identities = 129/579 (22%), Positives = 235/579 (40%), Gaps = 81/579 (13%)
Query: 725 VRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPKISNVG 784
+ V K++S+ K ++G+ P+ ++ +T +V D+ D P A +G
Sbjct: 21215 IEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPITVKELIITPEV-DLSDIPGAQVTVRIG 21273
Query: 785 EDSCTVQWEPPAYDGGQPILGYI---LERKKKKSYRWMRLNFDLIQELSHEARRMIEGVV 841
+ V E P +P + ++ L K+ + R+ + + + + A++ G
Sbjct: 21274 HN---VHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKN-AKKEHGGKY 21329
Query: 842 YEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTH-LAVEDVSDTTVSLKWRPPERVGAGG 900
+ AV I + P + + +GPPS+P + +++ +V L W PE G G
Sbjct: 21330 TVILDNAVCRIAV----PIT--VITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGE 21383
Query: 901 LDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTE 960
+ YS+E + W + T+ V +L A FRVRA N G ++
Sbjct: 21384 ITCYSIEKRETSQTNWKMVCSSVAR-TTFKVPNLVKDAEYQFRVRAENRYG------VSQ 21436
Query: 961 PVTVQEILQRPRLQLPRHL-RQTIQKKVGEPVNLL--------------IPFQGKPRPQV 1005
P+ I+ + + ++P + I + ++L + K R +
Sbjct: 21437 PLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSI 21496
Query: 1006 TWTKEG-QPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENME--------DKA 1056
W K P++G E RA V YQ V EN K
Sbjct: 21497 LWQKVNTSPISGREY-------------RATGLVEGLDYQFRVYAENSAGLSSPSDPSKF 21543
Query: 1057 TLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEW---- 1112
TL + VD P P + VT + L+W PP G +++ GY+++K W
Sbjct: 21544 TLAVSPVDPPGTPDYIDVTRE---TITLKWNPPLRDGGSKIVGYSIEKRQGNE-RWVRCN 21599
Query: 1113 FTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNY 1172
FT + + T V L G+ Y FR+ ++N VG + + + + PP
Sbjct: 21600 FTDVSECQYT---VTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENV---PP-- 21651
Query: 1173 KALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSK 1232
++F P + L+ +S G + + V+G P P+++WFK+G+++ + +
Sbjct: 21652 -IVEFG--PEYFDGLIIKS---GESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDV 21705
Query: 1233 QGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVR 1271
G +L +R G+Y A N G A+ E +++V+
Sbjct: 21706 LGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQ 21744
Score = 103 bits (257), Expect = 1e-21
Identities = 124/529 (23%), Positives = 187/529 (35%), Gaps = 95/529 (17%)
Query: 772 PDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDL-IQELS 830
P PA PK+ + S ++ W PAYDGG PI+GY++E K+ S W+R N +Q+
Sbjct: 13284 PGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTR 13343
Query: 831 HEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTT----- 885
E ++E Y+ RVYAVN IG S PS P P D+ T
Sbjct: 13344 FEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAG 13403
Query: 886 ------VSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGAR 939
V +K RPP ++ W L + + +K T
Sbjct: 13404 VTMRLYVPVKGRPPPKI------------------TWSKPNVNLRDRIGLDIKS--TDFD 13443
Query: 940 LLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKV----GEPVNLLI 995
R N G + T E ++ TI KV G PVN+ +
Sbjct: 13444 TFLRCENVNKYDAGKYILTLENSCGKK-------------EYTIVVKVLDTPGPPVNVTV 13490
Query: 996 PFQGKPRPQVTWTKE----GQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIEN 1051
K VTW G P+ V R++ ++ V + + + R+ N
Sbjct: 13491 KEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAER------KSWSTVTTECSKTSFRVAN 13544
Query: 1052 MEDKATLVLQVVDK--------------------PSPPQDLRVTDAWGLNVALEWKPPQD 1091
+E+ + +V + P P DL+V + ++ WK P
Sbjct: 13545 LEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVVDLKVRSVSKSSCSIGWKKPHS 13604
Query: 1092 VGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRA 1151
G + + GY V ++ +W V++ + +L G Y FRV ++N G
Sbjct: 13605 DGGSRIIGYVVDFLTEEN-KWQRVMKSLSLQYSA-KDLTEGKEYTFRVSAENENG----E 13658
Query: 1152 ATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPK 1211
T E + R + LD P S L ++G P P
Sbjct: 13659 GTPSEITVVARDDVVAPD-----LDLKGLPDLCYLAKENS-----NFRLKIPIKGKPAPS 13708
Query: 1212 ISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQG 1260
+SW K L D R + S TL + D G Y N+ G
Sbjct: 13709 VSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAG 13757
Score = 102 bits (255), Expect = 2e-21
Identities = 114/505 (22%), Positives = 205/505 (40%), Gaps = 45/505 (8%)
Query: 704 DTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVN 763
D G E + L T+ VRV + + G + E + V N GE + +
Sbjct: 7705 DGGAKIESYVIEMLKTGTDEWVRVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPS 7764
Query: 764 ------LTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYR 817
L + + P P ++ N+ +++ ++W P DGG PI YI+E++ +
Sbjct: 7765 EPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKG 7824
Query: 818 WMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMP---IGPPSEPT 874
W ++ +++ + EG +Y RV A NAIG S + + P P
Sbjct: 7825 WQTVD-TTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPY 7883
Query: 875 HLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDL 934
LAV DV+ V LKW PP+ G + Y +E + WV A + + V D+
Sbjct: 7884 ALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDV 7943
Query: 935 PTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLL 994
G + F+VRA N AG G P TE +++++ P L H+ +K + +
Sbjct: 7944 IEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIA--IAWK 8001
Query: 995 IPFQGKPRPQVTWTKEGQPLAGEE-VSIRNSPTDTILFIRAARRVHSGTYQVTVRIEN-- 1051
P + P + + E P+ E+ + + + P + F V Y + VR N
Sbjct: 8002 PPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAI 8061
Query: 1052 -MEDKATLVLQVVDKPS--------PPQDLRVTDAWGLNVALEWKP-PQDVGNTELWGYT 1101
+ + + + VV K D+ V + L++ + ++ P + G
Sbjct: 8062 GVSEPSEISENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKE 8121
Query: 1102 VQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIP 1161
V+ +D+ TM+ + H VP+ + + + + +N +G S A+ + + +P
Sbjct: 8122 VKASDRLTMK-----NDHISAHLEVPKSVRADAGIYTITLENKLG-SATASINVKVIGLP 8175
Query: 1162 RP--------------GITYEPPNY 1172
P +T+EPP +
Sbjct: 8176 GPCKDIKASDITKSSCKLTWEPPEF 8200
Score = 102 bits (255), Expect = 2e-21
Identities = 86/332 (25%), Positives = 131/332 (39%), Gaps = 39/332 (11%)
Query: 644 PPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPE 703
PP +HLD D + + G L SG P P V W K
Sbjct: 10512 PPTLHLD----FRDKLTIRVGEAFALTGRYSGKPKPKVSWFK------------------ 10549
Query: 704 DTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVN 763
D D E + R ++TT A++ D G Y V V+N G +
Sbjct: 10550 DEADVLE-----------DDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGF 10598
Query: 764 LTVKVIDVPDAPAAP-KISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLN 822
V V+D P P P V +D + W+PP DGG I YI+E+K+ WM +
Sbjct: 10599 CQVNVVDRPGPPVGPVSFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPVT 10658
Query: 823 FDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRP--SPASQPFMPIGPPSEPTHLAVED 880
+ + + +++EG Y R++A N G+S P S + + P P V +
Sbjct: 10659 -SASAKTTCKVSKLLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTE 10717
Query: 881 VSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQG-LTEHTSILVKDLPTGAR 939
V+ + + W P G + Y +E W + + +T V DL G +
Sbjct: 10718 VTKDSALVTWNKPHD-GGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQ 10776
Query: 940 LLFRVRAHNMAGPGAPVTTTEPVTVQEILQRP 971
FRV A N G G P ++PV ++ + +P
Sbjct: 10777 YEFRVSAENEIGIGDPSPPSKPVFAKDPIAKP 10808
Score = 102 bits (253), Expect = 3e-21
Identities = 150/635 (23%), Positives = 235/635 (37%), Gaps = 110/635 (17%)
Query: 680 TVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVE 739
TV+W +RP D D DKK L +V ET +D V
Sbjct: 20778 TVVW-----------SRPIADGGSDISGYFLEKRDKKSLGWF--KVLKETIRDTRQ-KVT 20823
Query: 740 GAEKEDEGVYTVTVKNPVGE------DQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWE 793
G + + Y V N G+ + ID P PA +I++ + S T+ W
Sbjct: 20824 GLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSITLGWS 20883
Query: 794 PPAYDGGQPILGYILERKKKKSYRWMRLNFD-LIQELSHEARRMIEGVVYEMRVYAVNAI 852
P YDGG + GY++E ++ + W ++ ++ + + GV Y RV AVN
Sbjct: 20884 KPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCA 20943
Query: 853 GMSRPSPASQPFMP---IGPPSEPTHLAV---------EDVSDTTVSLKWRPPERV---- 896
G P ++P + P +A+ EDV + K RPP V
Sbjct: 20944 GQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAGEDVQ-VLIPFKGRPPPTVTWRK 21002
Query: 897 ---GAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSIL----VKDLPTGARLLFRVRAHNM 949
G YS+E T+ +S+L V TG +L
Sbjct: 21003 DEKNLGSDARYSIEN---------------TDSSSLLTIPQVTRNDTGKYILTIEN---- 21043
Query: 950 AGPGAPVTTTEPVTVQEILQRP----RLQLPRHLRQTIQKKVGEP--------VNLLIPF 997
G G P ++T V ++L P +LQ+ R T+ P +N +I
Sbjct: 21044 -GVGEPKSSTVSV---KVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVI-- 21097
Query: 998 QGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKAT 1057
+ + + TW+ + + + T F R G + + T
Sbjct: 21098 EKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPC--------ETT 21149
Query: 1058 LVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLE 1117
++ + P+P +DL + D+ +V L W P G + + Y V++ K W +
Sbjct: 21150 EPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERKGKGEQTW-SHAG 21208
Query: 1118 HYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDF 1177
+ V +L + FRVF++N G SD T P+ + IT E +D
Sbjct: 21209 ISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSD--PVTIGPITVKELIITPE------VDL 21260
Query: 1178 SEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLT 1237
S+ P +V G+ L +G PKP ISW K+GL L E R + +T
Sbjct: 21261 SDIPG-----AQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKIT 21315
Query: 1238 LEIRKPCPFDGGIYVCRATNLQGEARCECRLEVRV 1272
L I+ GG Y N CR+ V +
Sbjct: 21316 LSIKNAKKEHGGKYTVILDN------AVCRIAVPI 21344
Score = 101 bits (252), Expect = 4e-21
Identities = 134/560 (23%), Positives = 208/560 (37%), Gaps = 74/560 (13%)
Query: 736 FTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPP 795
+TV+G ++ D Y V+ N VG+ + + K I D A P + D T++
Sbjct: 10471 YTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHLDFRDKLTIRV--- 10527
Query: 796 AYDGGQPILGYILERKKKKSYRWMRLNFDLIQE-LSH-------------EARRMIEG-- 839
G L K K W + D++++ +H +A+R G
Sbjct: 10528 ---GEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKY 10584
Query: 840 -VVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGA 898
VV E + G + + +P P+GP S ++V+ + + W+PP G
Sbjct: 10585 CVVVENSTGSRK--GFCQVNVVDRPGPPVGPVS------FDEVTKDYMVISWKPPLDDGG 10636
Query: 899 GGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTT 958
+ Y +E G W+ + T+ V L G +FR+ A N+ G
Sbjct: 10637 SKITNYIIEKKEVGKDVWMPVTSASAK-TTCKVSKLLEGKDYIFRIHAENLYG------I 10689
Query: 959 TEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLI---PFQG-KPRPQVTWTKEGQPL 1014
++P+ + + R ++P Q I +V + L+ P G KP K + +
Sbjct: 10690 SDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHDGGKPITNYILEKR-ETM 10748
Query: 1015 AGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENM--------EDKATLVLQVVDKP 1066
+ + P R + Y+ V EN K + KP
Sbjct: 10749 SKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKP 10808
Query: 1067 SPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVL---EHYRRTH 1123
SPP + D +V L W+PP+ G +++ GY V+ EW E T
Sbjct: 10809 SPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPETK 10868
Query: 1124 CVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGIT---YEPPNYKALDFSEA 1180
V L G Y FRV + N G SD P +P P + EPP LD + A
Sbjct: 10869 YKVTGLRDGQTYKFRVLAVNAAGESD-------PAHVPEPVLVKDRLEPPEL-ILDANMA 10920
Query: 1181 PSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEI 1240
+ + G T L ++G P PK++W K D AR + LEI
Sbjct: 10921 RE-------QHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGS--KLEI 10971
Query: 1241 RKPCPFDGGIYVCRATNLQG 1260
R DGGIY N G
Sbjct: 10972 RNAAHEDGGIYSLTVENPAG 10991
Score = 101 bits (251), Expect = 5e-21
Identities = 79/286 (27%), Positives = 133/286 (46%), Gaps = 11/286 (3%)
Query: 359 EKKSTAFQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAK 418
E+ F K LE V KG + L+ EL + + +V W K+G+ + + + IG
Sbjct: 4903 EELPVRFVKTLEEEVTVVKGQPLYLSCEL-NKERDVVWRKDGKIVVEKPGRIVPGVIGLM 4961
Query: 419 RTLTISQCSLADDAAYQCVVGGE---KCSTELFVKEPPVL---ITRPLEDQLVMVGQRVE 472
R LTI+ D Y V +CS+ VK V+ + +P+ DQ V
Sbjct: 4962 RALTINDADDTDAGTYTVTVENANNLECSS--CVKVVEVIRDWLVKPIRDQHVKPKGTAI 5019
Query: 473 FECEVSEEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGG 532
F C+++++ +KW K E+ E K +DG +L I AM ED YA+ G
Sbjct: 5020 FACDIAKDTPNIKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEGK 5079
Query: 533 QALAELIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKV 592
+ A+L + E+++E+ + I D+ + K+ A F E+S+ ++ G W G+ L P ++
Sbjct: 5080 RYPAKLTLGEREVELLKPIEDVTIYEKESASFDAEISEADIPGQWKLKGELLRPSPTCEI 5139
Query: 593 SHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDF 638
G LT+ V D+A + + +A L E+++DF
Sbjct: 5140 KAEGGKRFLTLHKV-KLDQAG-EVLYQALNAITTAILTVKEIELDF 5183
Score = 101 bits (251), Expect = 5e-21
Identities = 142/653 (21%), Positives = 242/653 (37%), Gaps = 78/653 (11%)
Query: 661 VVAGNKLRLDVPISGDP-----------APTVIWQKAITQGNKAPARPAPDAPEDTGDSD 709
++A NK + P+ +P AP ++T+ + P+ + +
Sbjct: 9986 IMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTG 10045
Query: 710 EWVFDKKLLCETEGRVRVETTKDRSI---FTVEGAEKEDEGVYTVTVKNPVGEDQVNL-- 764
W+ K + RV + K ++ + V G + + + V N G +L
Sbjct: 10046 YWLEMKDTTSKRWKRVNRDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPS 10105
Query: 765 ---TVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRL 821
T + P P PK+++ + S ++W PP DGG + GYI+E K++ W +
Sbjct: 10106 DPATARDPIAPPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKG 10165
Query: 822 NFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDV 881
++ + EG Y+ RV AVN G+ P + P V
Sbjct: 10166 KDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASV 10225
Query: 882 SDTTVSLKWRPPERVGAGGLDGYS--VEYCPEGCSEW---------VAALQGLTEHTSIL 930
D V V AGG+ V P W A ++ +S++
Sbjct: 10226 RDRIV---------VHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMV 10276
Query: 931 VKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKV--- 987
+K+ + ++ + A N AG + + V + P L +L K
Sbjct: 10277 IKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLA--HNLTNESCKLTWFS 10334
Query: 988 -----GEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGT 1042
G P+ + + + + WT + + +++ F R A G
Sbjct: 10335 PEDDGGSPITNYV-IEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGM 10393
Query: 1043 YQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTV 1102
+E E A ++ + + P P+DL V + V L W PP+ G +E+ Y +
Sbjct: 10394 GPF---VETSE--ALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVL 10448
Query: 1103 QKADKKTMEWFTVL-EHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIP 1161
+ T ++ V ++ V L G+ Y +RV + N+VG +P F
Sbjct: 10449 ESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQG-------KPSFCT 10501
Query: 1162 RPGITYE----PPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKN 1217
+P IT + PP LDF + ++ G L G PKPK+SWFK+
Sbjct: 10502 KP-ITCKDELAPPTLH-LDFRD---------KLTIRVGEAFALTGRYSGKPKPKVSWFKD 10550
Query: 1218 GLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
D+ ED R + + L LE K D G Y N G + C++ V
Sbjct: 10551 EADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNV 10603
Score = 100 bits (250), Expect = 7e-21
Identities = 118/495 (23%), Positives = 197/495 (39%), Gaps = 46/495 (9%)
Query: 736 FTVEGAEKEDEGVYTVTVKNPVG---EDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQW 792
F G E+ E + V+ +N VG +V+ D D P P+ V +S T+QW
Sbjct: 16095 FKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAIIVTRNSVTLQW 16154
Query: 793 EPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAI 852
+ P YDGG I GYI+E+K+ RWM+ +F I + E ++E YE RV A NA
Sbjct: 16155 KKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVIARNAA 16214
Query: 853 GMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEG 912
G+ S + +P ++++ T+ + +V A D Y P
Sbjct: 16215 GVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDA---DIYGK---PIP 16268
Query: 913 CSEWVAALQGLTEHTSILVKDLPTGARL----LFRVRAHNMAGPGAPVTTTEPVTVQ-EI 967
+W+ Q L+ + +K L RV + N V VTV ++
Sbjct: 16269 TIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKV 16328
Query: 968 LQRPRLQLPRHLRQTIQKKVGEPVNLL--IPFQGKPRPQVTWTKEGQPLAGEEVSIRNSP 1025
L RP P I E L P Q + + E + + ++ ++
Sbjct: 16329 LDRPG---PPEGPVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVDAN 16385
Query: 1026 TDTILFIRAARRVHSGTYQVTVRIEN-------MEDKATLVLQVVDKPSPPQDLRVTDAW 1078
T L + + + Y + N +E + + P P+ VT
Sbjct: 16386 VQT-LSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVT 16444
Query: 1079 GLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYR---RTHCVVPELIIGNGY 1135
++ + W+ P G +E+ GY ++K DK+ + W H R V LI + Y
Sbjct: 16445 KDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRC--HKRLIGELRLRVTGLIENHDY 16502
Query: 1136 YFRVFSQNMVGFSDRAATTK-----EPVFIPRPGITYEPPNYKALDFSEAP---SFTQPL 1187
FRV ++N G S+ + + +P++ P P P N K +D + + S+++P+
Sbjct: 16503 EFRVSAENAAGLSEPSPPSAYQKACDPIYKPGP-----PNNPKVIDITRSSVFLSWSKPI 16557
Query: 1188 VNRSV-IAGYTAMLC 1201
+ I GY C
Sbjct: 16558 YDGGCEIQGYIVEKC 16572
Score = 100 bits (248), Expect = 1e-20
Identities = 107/487 (21%), Positives = 186/487 (38%), Gaps = 42/487 (8%)
Query: 800 GQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSP 859
G+P+ L R MR N ++ E + + E V + Y + A S +
Sbjct: 20197 GKPLPKVTLSRDGVPLKATMRFNTEITAE--NLTINLKESVTADAGRYEITAANSSGTTK 20254
Query: 860 ASQPFMPIGPPSEPTH-LAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVA 918
A + + P PT + + D+++ +V+LKW PP+ G + Y + + W
Sbjct: 20255 AFINIVVLDRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTE 20314
Query: 919 ALQGLTEHTSILVKDLPTGARLLFRVRAHNMAG-----PGAPVTTTEPVTVQEILQRPRL 973
+ T + V L TG FR++A N G A VT P T P
Sbjct: 20315 -VSATVARTMMKVMKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTP-- 20371
Query: 974 QLPRHLRQTIQKKVGEPVN------LLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTD 1027
+ R++I EPV+ + + K R + W K ++ IR +
Sbjct: 20372 WVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQK------ANKLVIRTTHFK 20425
Query: 1028 TILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWK 1087
+ I A Y + + +D PP+++R+TD +V+L W+
Sbjct: 20426 -VTTISAGLIYEFRVYAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQ 20484
Query: 1088 PPQDVGNTELWGYTVQKADKKTMEWFTV-LEHYRRTHCVVPELIIGNGYYFRVFSQNMVG 1146
P G +++ GY V++ D W + T ++ L + Y FRVF++N VG
Sbjct: 20485 QPAFDGGSKITGYIVERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVG 20544
Query: 1147 FSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVI---AGYTAMLCCA 1203
+ P+ +D P PL V+ AG + L
Sbjct: 20545 SISNPSEVVGPI--------------TCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAG 20590
Query: 1204 VRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEAR 1263
+ G P P I W+K+ +L +A + + + ++ I+ + G Y + N G A
Sbjct: 20591 ISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRNAMGSAS 20650
Query: 1264 CECRLEV 1270
R+++
Sbjct: 20651 ATIRVQI 20657
Score = 99.4 bits (246), Expect = 2e-20
Identities = 77/249 (30%), Positives = 111/249 (44%), Gaps = 13/249 (5%)
Query: 391 DAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCV---VGGEKCSTEL 447
D E +W KNG +I+ S Y + L I + D A+ + GE S
Sbjct: 2060 DPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAF 2119
Query: 448 FVKEPPVLITRPLEDQLVMVGQR---VEFECEVSEEGAQVKWLKDGVELTREETFKYRFK 504
+ + LIT E Q V+ ++ FECE SE +VKW KDG+E+ E KYR
Sbjct: 2120 LLVQAKQLITFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEV--HEGDKYRMH 2177
Query: 505 KDGQRHHLIINEAMLEDAGHYALC---TSGGQALAELIVQEKKLEVYQSIADLMVGAKDQ 561
D + H L I DA Y+ + A+LIV+ +E + + D+ V
Sbjct: 2178 SDRKVHFLSILTIDTSDAEDYSCVLVEDENVKTTAKLIVEGAVVEFVKELQDIEVPESYS 2237
Query: 562 AVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEG- 620
+C VS EN+ G W N EL + + ++ LT+ DVT D+ +YSFV +G
Sbjct: 2238 GELECIVSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGK 2297
Query: 621 -FACNLSAK 628
C L K
Sbjct: 2298 KTTCKLKMK 2306
Score = 99.0 bits (245), Expect = 3e-20
Identities = 116/522 (22%), Positives = 200/522 (38%), Gaps = 83/522 (15%)
Query: 772 PDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDL-IQELS 830
P P+ PK+++ S ++ W P YDGG P+ GY++E K+ + W +Q
Sbjct: 18698 PGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQ 18757
Query: 831 HEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMP---IGPP-----SEPTHLAVEDVS 882
++ E Y R+ A+N+ G+ P+ + I PP ++ + V S
Sbjct: 18758 FTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRAS 18817
Query: 883 DTT---VSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGAR 939
T V++K RP V +G + A ++ + T +++ ++
Sbjct: 18818 ATLRLFVTIKGRPEPEVKWEKAEGILTDR---------AQIEVTSSFTMLVIDNVTRFDS 18868
Query: 940 LLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQG 999
+ + N +G + T V V+ +L P PVNL I
Sbjct: 18869 GRYNLTLENNSG-----SKTAFVNVR-VLDSP----------------SAPVNLTIREVK 18906
Query: 1000 KPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAA-RRVHSGTYQVTVRIENMED---- 1054
K ++W PL I N + R A + + + T RIEN+++
Sbjct: 18907 KDSVTLSWEP---PLIDGGAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSY 18963
Query: 1055 ----------------KATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELW 1098
+ T ++V + P PP + + D ++W+ P+ G +++
Sbjct: 18964 YFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKIT 19023
Query: 1099 GYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPV 1158
GY V+ K + +W T + + + L G Y FRV + N G SD P
Sbjct: 19024 GYVVEMQTKGSEKWSTCTQ-VKTLEATISGLTAGEEYVFRVAAVNEKGRSD-------PR 19075
Query: 1159 FIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNG 1218
+ P I A D PS P +V A + +G P+ ++W K+G
Sbjct: 19076 QLGVPVI--------ARDIEIKPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDG 19127
Query: 1219 LDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQG 1260
L E R + S + V +L I++ D G Y +N G
Sbjct: 19128 QTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAG 19169
Score = 99.0 bits (245), Expect = 3e-20
Identities = 115/467 (24%), Positives = 176/467 (37%), Gaps = 65/467 (13%)
Query: 824 DLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSD 883
DL L +A R+ G YE+++ NA+G + + Q GPP P + + V+
Sbjct: 20621 DLASILIKDADRLNSGC-YELKLR--NAMGSASATIRVQILDKPGPPGGP--IEFKTVTA 20675
Query: 884 TTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFR 943
++L WRPP G + Y VE W + L E I + G +FR
Sbjct: 20676 EKITLLWRPPADDGGAKITHYIVEKRETSRVVWSMVSEHL-EECIITTTKIIKGNEYIFR 20734
Query: 944 VRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRP 1003
VRA N G G P+ + V + +P + T K
Sbjct: 20735 VRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKIT-----------------KNSM 20777
Query: 1004 QVTWTKE----GQPLAGEEVSIRNSPT--------DTILFIR--AARRVHSGTYQVTVRI 1049
V W++ G ++G + R+ + +TI R + YQ V
Sbjct: 20778 TVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCA 20837
Query: 1050 ENMEDKATL--------VLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYT 1101
N + +D P PP +R+ D+ ++ L W P G + + GY
Sbjct: 20838 VNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYV 20897
Query: 1102 VQKADKKTMEWFTVLE--HYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVF 1159
V+ + EW TV R T VV L G YYFRV + N G EP+
Sbjct: 20898 VEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQG-------EPIE 20950
Query: 1160 IPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVI---AGYTAMLCCAVRGSPKPKISWFK 1216
+ P +A D EAP + R+ + AG + +G P P ++W K
Sbjct: 20951 MNEP--------VQAKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRK 21002
Query: 1217 NGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEAR 1263
+ +LG DAR+ + + L I + D G Y+ N GE +
Sbjct: 21003 DEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPK 21049
Score = 98.6 bits (244), Expect = 3e-20
Identities = 116/522 (22%), Positives = 197/522 (37%), Gaps = 81/522 (15%)
Query: 772 PDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDL-IQELS 830
P P PK+ ++ S + W P YDGG I GYI+E+ W I + +
Sbjct: 16533 PGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTN 16592
Query: 831 HEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PIGPPSEPTHLAVEDVSDTT-- 885
E +++E Y R+ A+N G+ + P + + P L + + +
Sbjct: 16593 IEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAG 16652
Query: 886 ------VSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGAR 939
V +K RP V G +DG + A + + TS+++ ++
Sbjct: 16653 GSLRLFVPIKGRPTPEVKWGKVDGEIRD---------AAIIDVTSSFTSLVLDNVNRYDS 16703
Query: 940 LLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQG 999
+ + N +G T + VTV+ +L P PVNL +
Sbjct: 16704 GKYTLTLENSSG-----TKSAFVTVR-VLDTP----------------SPPVNLKVTEIT 16741
Query: 1000 KPRPQVTWTKE----GQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVT--------- 1046
K +TW G + V R + + + H ++++
Sbjct: 16742 KDSVSITWEPPLLDGGSKIKNYIVEKREATRKS--YAAVVTNCHKNSWKIDQLQEGCSYY 16799
Query: 1047 --VRIEN-----MEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWG 1099
V EN + + ++V + P PP + V D +V+L W P+ G +++
Sbjct: 16800 FRVTAENEYGIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQ 16859
Query: 1100 YTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVF 1159
Y V+ K + +W + + V+ L G Y FRV + N G SD + V
Sbjct: 16860 YIVEMQAKHSEKW-SECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLA---VP 16915
Query: 1160 IPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGL 1219
I + EP P+F+ + SV G + + G PKP I+W K+GL
Sbjct: 16916 IVAKDLVIEP--------DVKPAFS----SYSVQVGQDLKIEVPISGRPKPTITWTKDGL 16963
Query: 1220 DLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGE 1261
L + R + + TL I++ DGG Y N+ G+
Sbjct: 16964 PLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQ 17005
Score = 98.6 bits (244), Expect = 3e-20
Identities = 125/521 (23%), Positives = 208/521 (39%), Gaps = 94/521 (18%)
Query: 736 FTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVI---DVPDAPAAPKISNVGEDSCTVQW 792
F + E+ E + V +N VG + + + D D P P+ V + T+QW
Sbjct: 17177 FKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPPGTPEPIMVKRNEITLQW 17236
Query: 793 EPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAI 852
P YDGG I GYI+E++ RWM+ +F + E + E YE RV A NA
Sbjct: 17237 TKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAA 17296
Query: 853 G-MSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSL--KWRPPERVGAGGLDGYSVEYC 909
G +S+PS ++ P A ++V +S+ K+R V AG + + +E
Sbjct: 17297 GAISKPSDSTGPI-----------TAKDEVELPRISMDPKFRDTIVVNAG--ETFRLEAD 17343
Query: 910 PEG----CSEWVAALQGLTEHTSILVKDLPTGARLLFR-----------VRAHNMAGPGA 954
G EW+ + + E +K+ A L+ + +RA N+AG
Sbjct: 17344 VHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAG--- 17400
Query: 955 PVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVN-LLIPFQGKPRPQVTWTKEGQP 1013
+ + PV V ++L RP G P + + + +TW+ Q
Sbjct: 17401 --SKSFPVNV-KVLDRP----------------GPPEGPVQVTGVTSEKCSLTWSPPLQD 17441
Query: 1014 LAGEEVS---IRNSPTDTILFIRAARRVHSGTYQVTVRIEN------------------M 1052
G ++S + T + + A V + + +VT +E +
Sbjct: 17442 -GGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPL 17500
Query: 1053 EDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEW 1112
E L+ P PP+ L VT+ ++ + W P G +E+ GY V+K D+ + W
Sbjct: 17501 ESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRW 17560
Query: 1113 FTV-LEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTK-----EPVFIPRPGIT 1166
V L + Y FRV ++N G + + T +PVF P P
Sbjct: 17561 IKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGP--- 17617
Query: 1167 YEPPNYKALDFSE---APSFTQPLVN-RSVIAGYTAMLCCA 1203
P N +D ++ ++ +P+ + S I GY +C A
Sbjct: 17618 --PTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEICKA 17656
Score = 97.4 bits (241), Expect = 8e-20
Identities = 105/411 (25%), Positives = 162/411 (39%), Gaps = 57/411 (13%)
Query: 876 LAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLP 935
L V V+ +L W P+ G + Y VE WV ++G S +V L
Sbjct: 22842 LTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLNWVI-VEGECPTLSYVVTRLI 22900
Query: 936 TGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLI 995
+FRVRA N GPG PV + EP+ + P I ++VG
Sbjct: 22901 KNNEYIFRVRAVNKYGPGVPVES-EPIVARNSFTIPS-------PPGIPEEVGT------ 22946
Query: 996 PFQGKPRPQVTWTKE----GQPLAGEEVSIRNSPT--------DTILF---IRAARRVHS 1040
GK + WTK G ++ V R + D +++ ++ +
Sbjct: 22947 ---GKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEG 23003
Query: 1041 GTYQVTVRIENME-----DKATLVLQVVDK---PSPPQDLRVTDAWGLNVALEWKPPQDV 1092
YQ V N +A+ + + P PP RV D +++L W P
Sbjct: 23004 CDYQFRVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYD 23063
Query: 1093 GNTELWGYTVQKADKKTMEWFTVLEH--YRRTHCVVPELIIGNGYYFRVFSQNMVGFSDR 1150
G T++ GY ++ +K T +W+ V + R T VP+L +G Y FRV + N+ G S+
Sbjct: 23064 GGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEY 23123
Query: 1151 AATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKP 1210
+ + E + R I D A + + R AG + L +V G P P
Sbjct: 23124 SESIAEIEPVERIEIP---------DLELADDLKKTVTIR---AGASLRLMVSVSGRPPP 23171
Query: 1211 KISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGE 1261
I+W K G+DL A +L ++ K +D G Y A N G+
Sbjct: 23172 VITWSKQGIDLASRAIIDTTESYSLLIVD--KVNRYDAGKYTIEAENQSGK 23220
Score = 95.1 bits (235), Expect = 4e-19
Identities = 68/224 (30%), Positives = 97/224 (43%), Gaps = 4/224 (1%)
Query: 391 DAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCSTELFVK 450
+A V W K G +I S K+ + G K L I+ D+ Y V G+K S LFV
Sbjct: 5207 EANVIWSK-GPDIIKSSDKFDIIADGKKHILVINDSQFDDEGVYTAEVEGKKTSARLFVT 5265
Query: 451 EPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKKDGQRH 510
+ PLEDQ V G+ F CE+S E V W K+ +L T +G+ H
Sbjct: 5266 GIRLKFMSPLEDQTVKEGETATFVCELSHEKMHVVWFKNDAKLHTSRTVL--ISSEGKTH 5323
Query: 511 HLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSD 570
L + E L+D + A+L V E + D KD+ KCEVS
Sbjct: 5324 KLEMKEVTLDDISQIKAQVKELSSTAQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVS- 5382
Query: 571 ENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADY 614
++V W K+G+E+VP + + G L I D+ +Y
Sbjct: 5383 KDVPVKWFKDGEEIVPSPKYSIKADGLRRILKIKKADLKDKGEY 5426
Score = 94.4 bits (233), Expect = 6e-19
Identities = 97/413 (23%), Positives = 161/413 (38%), Gaps = 53/413 (12%)
Query: 870 PSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSI 929
P P + +++VS ++++ W PPE G + Y VE + W Q + TSI
Sbjct: 19183 PGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQAVAR-TSI 19241
Query: 930 LVKDLPTGARLLFRVRAHNMAGPGA-----------PVTTTEPVTVQEILQRPRLQLPRH 978
+ L TG+ FRV A N G + P + P +++ + +
Sbjct: 19242 KIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTM--- 19298
Query: 979 LRQTIQKKVGEPVNLLIPF--QGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAAR 1036
T Q V + + +I + + K R + W+K + L + ++ S D L
Sbjct: 19299 -LVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANKILIAD-TQMKVSGLDEGLM----- 19351
Query: 1037 RVHSGTYQVTVRIENME-----DKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQD 1091
Y+ V EN+ K+ + D PP VT+ +V+L+W P
Sbjct: 19352 ------YEYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQPEVTNITRKSVSLKWSKPHY 19405
Query: 1092 VGNTELWGYTVQKADKKTMEWFTV-LEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDR 1150
G ++ GY V++ + W + + T+ V EL Y FRVF++N
Sbjct: 19406 DGGAKITGYIVERRELPDGRWLKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSE 19465
Query: 1151 AATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVI---AGYTAMLCCAVRGS 1207
+ + P+ + D E P + R VI AG + + G
Sbjct: 19466 PSESTGPIIVK--------------DDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGR 19511
Query: 1208 PKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQG 1260
P P ISW K+G+++ E AR + S L ++ D G YV N+ G
Sbjct: 19512 PLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAG 19564
Score = 93.2 bits (230), Expect = 1e-18
Identities = 98/428 (22%), Positives = 164/428 (38%), Gaps = 61/428 (14%)
Query: 868 GPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHT 927
GPP+ P + ++V+ +++L W PP+ G ++ Y VE + W + T
Sbjct: 15937 GPPTGPVKM--DEVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTW-QIVSATVART 15993
Query: 928 SILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQ----LPRHLRQTI 983
+I L TG FR+ A N G + + EP Q + P + R ++
Sbjct: 15994 TIKACRLKTGCEYQFRIAAENRYGKSTYLNS-EPTVAQYPFKVPGPPGTPVVTLSSRDSM 16052
Query: 984 QKKVGEPVN------LLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARR 1037
+ + EP++ + + K R + W K + +P F +
Sbjct: 16053 EVQWNEPISDGGSRVIGYHLERKERNSILWVK-----------LNKTPIPQTKF-KTTGL 16100
Query: 1038 VHSGTYQVTVRIENME--------DKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPP 1089
Y+ V EN+ + + D P P+ + VT +V L+WK P
Sbjct: 16101 EEGVEYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAIIVTRN---SVTLQWKKP 16157
Query: 1090 QDVGNTELWGYTVQKADKKTMEWFTV-LEHYRRTHCVVPELIIGNGYYFRVFSQNMVGF- 1147
G +++ GY V+K + W + TH V L+ + Y FRV ++N G
Sbjct: 16158 TYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVF 16217
Query: 1148 -----SDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCC 1202
S A T ++ V PR S P + +V V AG + +
Sbjct: 16218 SEPSESTGAITARDEVDPPR--------------ISMDPKYKDTIV---VHAGESFKVDA 16260
Query: 1203 AVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEA 1262
+ G P P I W K +L AR + S +L ++ D G Y+ +A N+ GE
Sbjct: 16261 DIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGER 16320
Query: 1263 RCECRLEV 1270
++V
Sbjct: 16321 SVTVNVKV 16328
Score = 92.4 bits (228), Expect = 2e-18
Identities = 114/418 (27%), Positives = 156/418 (37%), Gaps = 43/418 (10%)
Query: 870 PSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGC--SEWVAALQGLTEHT 927
P P + ED+ T+V KW PP G + Y++E + SEW+ L H
Sbjct: 8497 PGPPINFVFEDIRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWIVVTSTL-RHC 8555
Query: 928 SILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKV 987
V L G LFRVRA N GPG P + +P+ ++ P K +
Sbjct: 8556 KYSVTKLIEGKEYLFRVRAENRFGPGPPCVS-KPLVAKDPFGPP---------DAPDKPI 8605
Query: 988 GEPV--NLLIPFQGKPR----PQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSG 1041
E V N ++ +P+ P + + E + + S N L +
Sbjct: 8606 VEDVTSNSMLVKWNEPKDNGSPILGYWLEKREVNSTHWSRVNKSLLNALKANVDGLLEGL 8665
Query: 1042 TYQVTVRIENMEDKATL--------VLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVG 1093
TY V EN + P PP RVTD + LEW+PP G
Sbjct: 8666 TYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIP-RVTDTSSTTIELEWEPPAFNG 8724
Query: 1094 NTELWGYTVQKADKKTMEWFTVLEHYRRTH-CVVPELIIGNGYYFRVFSQNMVGFSDRAA 1152
E+ GY V K T EW E + V E+ G Y RV + N G
Sbjct: 8725 GGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGEGPPGE 8784
Query: 1153 TTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKI 1212
T +PV + P EPP + LD S ++AG T + V G P P
Sbjct: 8785 T--QPVTVAEP---QEPPAVE-LDVSVKGGI-------QIMAGKTLRIPAVVTGRPVPTK 8831
Query: 1213 SWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
W K +L +D R + + L I+ D G YV ATN G R+EV
Sbjct: 8832 VWTKEEGELDKD-RVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEV 8888
Score = 92.4 bits (228), Expect = 2e-18
Identities = 101/405 (24%), Positives = 158/405 (39%), Gaps = 35/405 (8%)
Query: 867 IGPPSEPTH-LAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTE 925
+G P PT + ++V+ ++LKW PP+ G + Y +E ++WV + +
Sbjct: 13768 VGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCASAV-Q 13826
Query: 926 HTSILVKDLPTGARLLFRVRAHNMAGPGA-----PVTTTEPVTVQEILQRPRLQLPRH-- 978
T+ V L G FRV A N G G P+ P V + P + RH
Sbjct: 13827 KTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNIVDVRHDS 13886
Query: 979 --LRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQ-PLAGEEVSIRNSPTDTILFIRAA 1035
L T KK G + K R + W + + P+ + + R
Sbjct: 13887 VSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLEYEFRVM 13946
Query: 1036 RRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNT 1095
+G V ++ + + L +D P P+ + +T +V L W P+ G
Sbjct: 13947 AINLAG-----VGKPSLPSEPVVALDPIDPPGKPEVINITRN---SVTLIWTEPKYDGGH 13998
Query: 1096 ELWGYTVQKADKKTMEWFTVLEHYRRTHCV--VPELIIGNGYYFRVFSQNMVGFSDRAAT 1153
+L GY V+K D + W H C V +L+ G Y FR+ ++N G +
Sbjct: 13999 KLTGYIVEKRDLPSKSWMKA-NHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSE 14057
Query: 1154 TKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAML-CCAVRGSPKPKI 1212
+ E + YE P LD P+ L ++ AG T +L ++ G P PK
Sbjct: 14058 STETIICKDE---YEAPTI-VLD----PTIKDGL---TIKAGDTIVLNAISILGKPLPKS 14106
Query: 1213 SWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATN 1257
SW K G D+ ++ S L I+ D G Y ATN
Sbjct: 14107 SWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATN 14151
Score = 91.3 bits (225), Expect = 5e-18
Identities = 65/244 (26%), Positives = 113/244 (46%), Gaps = 6/244 (2%)
Query: 374 QVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAA 433
+V +G ++L V+++ E W+K+GQE+Q S +I L I + D
Sbjct: 2320 KVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHIVID-KQSHMLLIEDMTKEDAGN 2378
Query: 434 YQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVS-EEGAQVKWLKDGVE 492
Y + ST V V + PL+D V+ G + EC+VS + VKW + +
Sbjct: 2379 YSFTIPALGLSTSGRVSVYSVDVITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQ 2438
Query: 493 LTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIA 552
+ ++ + K G + L+IN D G Y L + L V+ K+++ + +
Sbjct: 2439 IKPDDRVQAIVK--GTKQRLVINRTHASDEGPYKLIVGRVETNCNLSVE--KIKIIRGLR 2494
Query: 553 DLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEA 612
DL VF+ E+S + +W KE+ P S+ K+ G+++KLT+ ++ DE
Sbjct: 2495 DLTCTETQNVVFEVELSHSGIDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEG 2554
Query: 613 DYSF 616
Y+F
Sbjct: 2555 KYTF 2558
Score = 91.3 bits (225), Expect = 5e-18
Identities = 107/447 (23%), Positives = 169/447 (37%), Gaps = 74/447 (16%)
Query: 846 VYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYS 905
V A N+ G + + + GPP P ++VS V + W PP G + Y
Sbjct: 18079 VTATNSAGTATENLSVIVLEKPGPPVGPVRF--DEVSADFVVISWEPPAYTGGCQISNYI 18136
Query: 906 VEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQ 965
VE + W + T+I + L TG FR+ A N G AP+ + + V VQ
Sbjct: 18137 VEKRDTTTTTW-HMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKSAPLDS-KAVIVQ 18194
Query: 966 EILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKE----GQPLAGEEVSI 1021
+ P G P + K + V W + G + G +
Sbjct: 18195 YPFKEP----------------GPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQ 18238
Query: 1022 RNSPTDTILFIRAARRVHSGT------------YQVTVRIENME--------DKATLVLQ 1061
+ ++IL+++ + T Y+ V EN+ + +
Sbjct: 18239 KEK--NSILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARD 18296
Query: 1062 VVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTV-LEHYR 1120
D P P+ + +T NV L+WK P G +++ GY V+K D W +
Sbjct: 18297 PCDPPGRPEAIVITRN---NVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVL 18353
Query: 1121 RTHCVVPELIIGNGYYFRVFSQNMVGF------SDRAATTKEPVFIPRPGITYEPPNYKA 1174
T V L+ Y FRV ++N G S A T ++ + P + P YK
Sbjct: 18354 ETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLD---PKYKD 18410
Query: 1175 LDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGED-ARFRMFSKQ 1233
+ V AG T +L +RG P P + W K+G +L E AR + S
Sbjct: 18411 VIV--------------VHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTI 18456
Query: 1234 GVLTLEIRKPCPFDGGIYVCRATNLQG 1260
TL ++ DGG Y+ + +N+ G
Sbjct: 18457 QKTTLVVKDCIRTDGGQYILKLSNVGG 18483
Score = 90.9 bits (224), Expect = 7e-18
Identities = 68/227 (29%), Positives = 112/227 (49%), Gaps = 8/227 (3%)
Query: 386 ELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSL--ADDAAYQCVVGGEKC 443
E+++ D +W G+ ++ S + I ++ G KR LT+ + L A + YQ +
Sbjct: 5114 EISEADIPGQWKLKGELLRPSPTCEI-KAEGGKRFLTLHKVKLDQAGEVLYQAL--NAIT 5170
Query: 444 STELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRF 503
+ L VKE + PL+D V ++ FEC ++ E A V W K G ++ + K+
Sbjct: 5171 TAILTVKEIELDFAVPLKDVTVPERRQARFECVLTRE-ANVIWSK-GPDIIKSSD-KFDI 5227
Query: 504 KKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAV 563
DG++H L+IN++ +D G Y G + A L V +L+ + D V + A
Sbjct: 5228 IADGKKHILVINDSQFDDEGVYTAEVEGKKTSARLFVTGIRLKFMSPLEDQTVKEGETAT 5287
Query: 564 FKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPAD 610
F CE+S E + VW KN +L + +S G+ HKL + +VT D
Sbjct: 5288 FVCELSHEKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDD 5334
Score = 90.5 bits (223), Expect = 9e-18
Identities = 108/430 (25%), Positives = 157/430 (36%), Gaps = 64/430 (14%)
Query: 868 GPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHT 927
GPP P + D+ SL W P G + Y VE C +WV AL +T+ T
Sbjct: 12688 GPPQPP--FDISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTK-T 12744
Query: 928 SILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKV 987
S V L G +FRVRA N G P+T+ P+ + Q
Sbjct: 12745 SCRVGKLIPGQEYIFRVRAENRFGISEPLTS-----------------PKMVAQFPFGVP 12787
Query: 988 GEPVNLLIPFQGKPRPQVTWTKE----GQPLAGEEVSIRNSPTDTILFIRAARR-VHSGT 1042
EP N + K V W + G P+ G I +++L+++A V S
Sbjct: 12788 SEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIG--YLIERKERNSLLWVKANDTLVRSTE 12845
Query: 1043 YQVTVRIENME----------------DKATLVLQVVDKPSPPQDLRVTDAWGLNVALEW 1086
Y +E +E K T + PP V D V+L W
Sbjct: 12846 YPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIW 12905
Query: 1087 KPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNG------YYFRVF 1140
P+ G +++ GY V+ +W + H + E G Y FR
Sbjct: 12906 ARPKHDGGSKIIGYFVEACKLPGDKW---VRCNTAPHQIPQEEYTATGLEEKAQYQFRAI 12962
Query: 1141 SQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAML 1200
++ V S + + +PV I + PP +D S A +V AG L
Sbjct: 12963 ARTAVNISPPSEPS-DPVTILAENV---PPR---IDLSVAMKSLL-----TVKAGTNVCL 13010
Query: 1201 CCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQG 1260
V G P P +SW K+G L +M ++ + TLE+ D G Y A N G
Sbjct: 13011 DATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSG 13070
Query: 1261 EARCECRLEV 1270
+L+V
Sbjct: 13071 SKSATIKLKV 13080
Score = 90.5 bits (223), Expect = 9e-18
Identities = 111/461 (24%), Positives = 182/461 (39%), Gaps = 71/461 (15%)
Query: 727 VETTKDRSIFTVEGAEKEDEGVYTVTVKNPVG---EDQVNLTVKVIDVPDAPAAPKISNV 783
++ TK ++ EG E E + V+ +N VG +V+ D D P P+ +
Sbjct: 18254 IQDTKFKTTGLDEGLEYE----FKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAIVI 18309
Query: 784 GEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYE 843
++ T++W+ PAYDGG I GYI+E+K RWM+ +F + E ++E YE
Sbjct: 18310 TRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGLVEDQRYE 18369
Query: 844 MRVYAVNAIG-MSRPSPASQPFM---PIGPPSEPTHLAVEDV-----SDTTV---SLKWR 891
RV A NA G S PS +S I P+ +DV +T V ++ +
Sbjct: 18370 FRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVHAGETFVLEADIRGK 18429
Query: 892 PPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAG 951
P V DG +E ++ + T+++VKD + ++ N+ G
Sbjct: 18430 PIPDV-VWSKDGKELEETAARME-----IKSTIQKTTLVVKDCIRTDGGQYILKLSNVGG 18483
Query: 952 PGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVN-LLIPFQGKPRPQVTWTKE 1010
T + P+TV ++L RP G P L + + + W
Sbjct: 18484 -----TKSIPITV-KVLDRP----------------GPPEGPLKVTGVTAEKCYLAWNPP 18521
Query: 1011 GQPLAGEEVS---IRNSPTDTILFIRAARRVHSGTYQVTVRI------------------ 1049
Q G +S I T + + + + V + Y+VT +
Sbjct: 18522 LQD-GGANISHYIIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGIG 18580
Query: 1050 ENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKT 1109
E +E P PP V+ ++ + W P D G TE+ GY ++K DK+
Sbjct: 18581 EPLESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEG 18640
Query: 1110 MEWFTV-LEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSD 1149
+ W + V L G+ Y FRV ++N G +
Sbjct: 18641 VRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGE 18681
Score = 89.0 bits (219), Expect = 3e-17
Identities = 99/416 (23%), Positives = 166/416 (39%), Gaps = 40/416 (9%)
Query: 359 EKKSTAFQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAK 418
E + F+K ++ + K + E+++ D V+W+K+ QE+Q++ I +
Sbjct: 3008 EARHIEFRKHIKDIKVLEK-KRAMFECEVSEPDITVQWMKDDQELQITDRIKIQKEKYVH 3066
Query: 419 RTLTISQCSLADDAAYQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVS 478
R L I ++D Y V GG + +LFV+ V I ++ V+ QR E EV+
Sbjct: 3067 RLL-IPSTRMSDAGKYTVVAGGNVSTAKLFVEGRDVRIRSIKKEVQVIEKQRAVVEFEVN 3125
Query: 479 EEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAEL 538
E+ W KDG+E+ + ++++ + + H + I+E DAG Y ++ L
Sbjct: 3126 EDDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVTL 3185
Query: 539 IVQ-EKKLEVYQSIADLMVGAKDQAVFKCEVSDENVRGV-WLKNGKELVPDSRIKVSHIG 596
V + +V Q + + V + A F +S + W K + L + K H G
Sbjct: 3186 YVNAPEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDG 3245
Query: 597 RVHKLTIDDVTPADEADYSFVPEG--FACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGR 654
+ + L + + P D A Y+ + SA L +EV P QE P
Sbjct: 3246 QEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLS-VEVPEVVSPDQEMPVYPPAIITP 3304
Query: 655 IPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFD 714
+ DT V G R +SG + K D
Sbjct: 3305 LQDT-VTSEGQPARFQCRVSGTDLKVSWYSK----------------------------D 3335
Query: 715 KKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGE--DQVNLTVKV 768
KK+ + R+ +D + A EDEG YT N VG+ NL+++V
Sbjct: 3336 KKI--KPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEV 3389
Score = 89.0 bits (219), Expect = 3e-17
Identities = 135/650 (20%), Positives = 234/650 (36%), Gaps = 98/650 (15%)
Query: 661 VVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPD------------APEDTGDS 708
V A NK + P+ DP V+ Q T + AP P P PE G S
Sbjct: 21821 VSAVNKFGVGRPLDSDP---VVAQIQYTVPD-APGIPEPSNITGNSITLTWARPESDGGS 21876
Query: 709 D--EWVFDKKLLCETEGRVRVETTKDRSI----FTVEGAEKEDEGVYTVTVKNPVGEDQV 762
+ +++ +++ E + V+ R I F V G + +E + V +N G
Sbjct: 21877 EIQQYILERR---EKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVGPA 21933
Query: 763 NLTVKVI------DVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSY 816
+ ++I + P P K+++ + + +++W P +DGG I+GYI+E K
Sbjct: 21934 SGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLG 21993
Query: 817 RWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIG----------MSRPSPASQPFMP 866
W ++N + + + + G Y+ RV A+N G + + P +
Sbjct: 21994 DWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIKAVDRLTAPELD 22053
Query: 867 IGPPSEPTHLAVEDVS---------DTTVSLKWRPPE-----RVGAGGLDGYSVEYCPEG 912
I + TH+ S T + W P+ R D +S E
Sbjct: 22054 IDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADIHTTDSFST-LTVEN 22112
Query: 913 CSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQ--R 970
C+ A LT V++ + F V+ + GP P+T + L
Sbjct: 22113 CNRNDAGKYTLT------VENNSGSKSITFTVKVLDTPGPPGPITFKDVTRGSATLMWDA 22166
Query: 971 PRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTIL 1030
P L + + +K + + +W + + + +
Sbjct: 22167 PLLDGGARIHHYVVEK-------------REASRRSWQVISEKCTRQIFKVNDLAEGVPY 22213
Query: 1031 FIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQ 1090
+ R + Y V E E + ++P+PP+ L V D + L W P
Sbjct: 22214 YFRVSA---VNEYGVGEPYEMPEP-----IVATEQPAPPRRLDVVDTSKSSAVLAWLKPD 22265
Query: 1091 DVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDR 1150
G + + GY ++ K + W H ++ V L+ Y FRV ++N G+S+
Sbjct: 22266 HDGGSRITGYLLEMRQKGSDFWVEA-GHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEP 22324
Query: 1151 AATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKP 1210
V I P I EP ++ T L+ AG + + G P P
Sbjct: 22325 REAFSS-VIIKEPQI--EPT-------ADLTGITNQLITCK--AGSPFTIDVPISGRPAP 22372
Query: 1211 KISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQG 1260
K++W + L E R + + + TL ++ D G Y N G
Sbjct: 22373 KVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAG 22422
Score = 86.7 bits (213), Expect = 1e-16
Identities = 71/263 (26%), Positives = 119/263 (45%), Gaps = 10/263 (3%)
Query: 375 VSKGHKIRLTVELADHDA-EVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAA 433
V +G K L +++ D VKW N ++I+ G K+ L I++ +D+
Sbjct: 2410 VIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVK-GTKQRLVINRTHASDEGP 2468
Query: 434 YQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVEL 493
Y+ +VG + + L V++ + I R L D Q V FE E+S G V W E+
Sbjct: 2469 YKLIVGRVETNCNLSVEK--IKIIRGLRDLTCTETQNVVFEVELSHSGIDVLWNFKDKEI 2526
Query: 494 TREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIAD 553
+ + KY+ + G+ + L + M +D G Y +L V + + + D
Sbjct: 2527 --KPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTFYAGENMTSGKLTVAGGAIS--KPLTD 2582
Query: 554 LMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEAD 613
V +AVF+CEV++ + +G WL++GK L + I+ G +L I D +
Sbjct: 2583 QTVAESQEAVFECEVANPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGE 2642
Query: 614 YSFVPEGFACNLSAKLHFMEVKI 636
Y++ + SAKL VKI
Sbjct: 2643 YTY--KVATSKTSAKLKVEAVKI 2663
Score = 86.7 bits (213), Expect = 1e-16
Identities = 156/799 (19%), Positives = 296/799 (37%), Gaps = 121/799 (15%)
Query: 1 MPEPGKKPVSAFSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASN--KYGLA 58
+P ++ F K S E+A + V E+ RA +V W + G + + ++ +
Sbjct: 26407 LPVSAPPKITQFLKAEASKEIAKLT-CVVESSVLRAK-EVTWYKDGKKLKENGHFQFHYS 26464
Query: 59 TEGTRHTLTVREVGPADQGSYAVI----AGSSKVKFDLKVIEAEKAEPMLAPAPAPAEAT 114
+GT + L + + +DQG Y G+SK +A
Sbjct: 26465 ADGT-YELKINNLTESDQGEYVCEISGEGGTSKTNLQFM-----------------GQAF 26506
Query: 115 GAPGEAPAPAAELGESAPSPKGSSSAALNGPTPGAPDDPIG---LFVMRPQDGEVTVGGS 171
+ E + +E +S K + S P AP+ PI + V QD V+
Sbjct: 26507 KSIHEKVSKISETKKS--DQKTTESTVTRKTEPKAPE-PISSKPVIVTGLQDTTVSSDSV 26563
Query: 172 ITFSARVAGASLLKPPVVKWFK-GKWVDLSSKVGQHLQLHDSYDRASKVYLFELHITDAQ 230
F+ + G P W K GK + K S D+ + E+H TD
Sbjct: 26564 AKFAVKATGEPR---PTAIWTKDGKAITQGGKYKL------SEDKGG--FFLEIHKTDTS 26612
Query: 231 PAFTGSYRCEVSTKDKFDCSNFNLTVHEAMGTGDLDLLSAFRRTSLAGGGRRISDSHEDT 290
+ G Y C V S+ LT+ +A+ + +S + + + + +
Sbjct: 26613 DS--GLYTCTVKNSAGSVSSSCKLTI-KAIKDTEAQKVSTQKTSEITPQKKAVVQEEISQ 26669
Query: 291 GILDFSSLLKKRDSFRTPRDSKLEAPAEEDVWEILRQAPPSEYERIAFQYGVTDLRGMLK 350
L S +K ++ + + E ++ + E ++++ + E+ +T
Sbjct: 26670 KALR-SEEIKMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEEITKT----- 26723
Query: 351 RLKGMRRDEKKSTAFQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKY 410
+E ++ A K +++G ++ L +A +VKW+ NG E+ S +Y
Sbjct: 26724 ---SQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAGA-TDVKWVLNGVELTNS-EEY 26778
Query: 411 IFESIGAKRTLTISQCSLADDAAYQCV----VGGEKCSTELF----VKEPPVLITRPLED 462
+ G+ +TLTI Q S D+ C+ G KC +L + + P I++P
Sbjct: 26779 RYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTLSKELSDAPAFISQP-RS 26837
Query: 463 QLVMVGQRVEFECEVS-EEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLED 521
Q + GQ V F CE+S E +++W K+ + ++ + + L I A + D
Sbjct: 26838 QNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVS--ISRSRNVYSLEIRNASVSD 26895
Query: 522 AGHYAL--------CTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDENV 573
+G Y + C++ + +V+E EV ++ + S ++V
Sbjct: 26896 SGKYTIKAKNFRGQCSATASLMVLPLVEEPSREV-------VLRTSGDTSLQGSFSSQSV 26948
Query: 574 RGVWLKNGKELVPDSRIKVSHIGRVH--KLTIDDVTPADEADYSFVPEGF--ACNLSAKL 629
+ K S S + + ++ ++ E+ F N++
Sbjct: 26949 QMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQLE 27008
Query: 630 HFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQ 689
+ R PPKI +P I + G L + +G+P P V W
Sbjct: 27009 SSTSKMLKAGIRGIPPKIE-----ALPSDISIDEGKVLTVACAFTGEPTPEVTWSCG--- 27060
Query: 690 GNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVY 749
+K+ + +GR +E T D + + +K+D G+Y
Sbjct: 27061 ------------------------GRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLY 27096
Query: 750 TVTVKNPVGEDQVNLTVKV 768
T+++ N G D + + +
Sbjct: 27097 TLSLGNEFGSDSATVNIHI 27115
Score = 86.3 bits (212), Expect = 2e-16
Identities = 67/265 (25%), Positives = 115/265 (43%), Gaps = 6/265 (2%)
Query: 375 VSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAY 434
V +G EL+ V W KN ++ S + + S G L + + +L D +
Sbjct: 5280 VKEGETATFVCELSHEKMHVVWFKNDAKLHTSRT-VLISSEGKTHKLEMKEVTLDDISQI 5338
Query: 435 QCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELT 494
+ V + +L V E T L D+ + + +CEVS++ VKW KDG E+
Sbjct: 5339 KAQVKELSSTAQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVSKD-VPVKWFKDGEEIV 5397
Query: 495 REETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADL 554
KY K DG R L I +A L+D G Y + A + V+ + ++V + + +
Sbjct: 5398 PSP--KYSIKADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIKVEKPLYGV 5455
Query: 555 MVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADY 614
V + A F+ E+S+ +V G W G+ L ++ G+ H L + + +
Sbjct: 5456 EVFVGETAHFEIELSEPDVHGQWKLKGQPLTASPDCEIIEDGKKHILILHNCQLGMTGEV 5515
Query: 615 SFVPEGFACNLSAKLHFMEVKIDFV 639
SF + +A L E+ + F+
Sbjct: 5516 SF--QAANAKSAANLKVKELPLIFI 5538
Score = 85.9 bits (211), Expect = 2e-16
Identities = 106/418 (25%), Positives = 147/418 (35%), Gaps = 55/418 (13%)
Query: 868 GPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHT 927
GPP+ P + ++VS V+ W PPE G + Y VE + WV L T
Sbjct: 14855 GPPTGP--IKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVE-LATTVIRT 14911
Query: 928 SILVKDLPTGARLLFRVRAHNMAGPGAPVTTT-----EPVTVQEILQRPRLQLPRHLRQT 982
+ L TG FRV+A N G G +T+ P V P++ T
Sbjct: 14912 TYKATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMT 14971
Query: 983 IQ-----KKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARR 1037
I G P+ L + K R + W + L + + TD I
Sbjct: 14972 ISWHEPLSDGGSPI-LGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGI-------- 15022
Query: 1038 VHSGTYQVTVRIENMEDKAT--------LVLQVVDKPSPPQDLRVTDAWGLNVALEWKPP 1089
Y+ V ENM K+ L L +D P P L +T V L+W P
Sbjct: 15023 ----AYEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRH---TVTLKWAKP 15075
Query: 1090 QDVGNTELWGYTVQKADKKTMEWFTV-LEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFS 1148
+ G ++ Y V+K D W + V L Y FRV ++N
Sbjct: 15076 EYTGGFKITSYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKN----- 15130
Query: 1149 DRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVI---AGYTAMLCCAVR 1205
AA P P IT D EAP + + + AG L V
Sbjct: 15131 --AAGAISPPSEPSDAITCR-------DDVEAPKIKVDVKFKDTVILKAGEAFRLEADVS 15181
Query: 1206 GSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEAR 1263
G P P + W K+G +L A+ + L + D G Y ATN G A+
Sbjct: 15182 GRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGGFAK 15239
Score = 85.9 bits (211), Expect = 2e-16
Identities = 99/432 (22%), Positives = 160/432 (37%), Gaps = 45/432 (10%)
Query: 846 VYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYS 905
+ N +G S PP P +DVS +++L W PP G + Y
Sbjct: 16997 ITVANVVGQKTASIEIVTLDKPDPPKGPVKF--DDVSAESITLSWNPPLYTGGCQITNYI 17054
Query: 906 VEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQ 965
V+ + W + T++ V L TG FR+ A N G + + +P+ Q
Sbjct: 17055 VQKRDTTTTVW-DVVSATVARTTLKVTKLKTGTEYQFRIFAENRYGQSFALES-DPIVAQ 17112
Query: 966 EILQRPRLQ----LPRHLRQTIQKKVGEPVN------LLIPFQGKPRPQVTWTKEGQPLA 1015
+ P + ++ + EPVN + + K R + WTK + +
Sbjct: 17113 YPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKTII 17172
Query: 1016 GEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVT 1075
+ + + I + RV++ V V + + + D P P+ + V
Sbjct: 17173 HDTQFKAQNLEEGIEY---EFRVYAENI-VGVGKASKNSECYVARDPCDPPGTPEPIMVK 17228
Query: 1076 DAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTV-LEHYRRTHCVVPELIIGNG 1134
+ L+W P G + + GY V+K D W + T V L
Sbjct: 17229 RN---EITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQR 17285
Query: 1135 YYFRVFSQNMVGFSDRAA------TTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLV 1188
Y FRV ++N G + + T K+ V +PR S P F +V
Sbjct: 17286 YEFRVIAKNAAGAISKPSDSTGPITAKDEVELPR--------------ISMDPKFRDTIV 17331
Query: 1189 NRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDG 1248
V AG T L V G P P I W + ++ E AR + + L ++ DG
Sbjct: 17332 ---VNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDG 17388
Query: 1249 GIYVCRATNLQG 1260
G Y+ RA+N+ G
Sbjct: 17389 GQYILRASNVAG 17400
Score = 85.5 bits (210), Expect = 3e-16
Identities = 109/404 (26%), Positives = 150/404 (37%), Gaps = 61/404 (15%)
Query: 847 YAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSV 906
Y V A + A + P +L + DVS ++ W PPE G + Y +
Sbjct: 11969 YVVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYIL 12028
Query: 907 EYCPEGCSEWVA-ALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQ 965
E C W + LT T+ V L G +FRVRA N G G P T ++PV
Sbjct: 12029 EKCETKRMVWSTYSATVLTPGTT--VTRLIEGNEYIFRVRAENKIGTGPP-TESKPV--- 12082
Query: 966 EILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKE----GQPLAG----- 1016
+ +T K G P + K V W G+ + G
Sbjct: 12083 -------------IAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLEK 12129
Query: 1017 -EEVSIRNSPTDTILFIRAARRVHS----GTYQVTVRIEN--------MEDKATLVLQVV 1063
E+ S R P + +V + YQ V+ EN + + + +
Sbjct: 12130 KEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPI 12189
Query: 1064 DKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQK----ADKKTMEWF---TVL 1116
+ P PP + RV D ++ L W P G + GY V+ AD E +
Sbjct: 12190 EPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAA 12249
Query: 1117 EHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALD 1176
R V L Y FRV +QN VG R A KE + +P EPP LD
Sbjct: 12250 AQLVRKEFTVTSLDENQEYEFRVCAQNQVGIG-RPAELKEAI---KPKEILEPPEID-LD 12304
Query: 1177 FSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLD 1220
S + LV V AG L VRG P PK++W K G+D
Sbjct: 12305 AS-----MRKLV--IVRAGCPIRLFAIVRGRPAPKVTWRKVGID 12341
Score = 85.5 bits (210), Expect = 3e-16
Identities = 110/462 (23%), Positives = 181/462 (39%), Gaps = 59/462 (12%)
Query: 769 IDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQE 828
+D D P P N+ + T++W P Y GG I YI+E++ + RW++ NF I E
Sbjct: 15049 LDPIDPPGKPVPLNITRHTVTLKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILE 15108
Query: 829 LSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSL 888
+ E YE RV A NA G P + E + V+ TV L
Sbjct: 15109 NEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVIL 15168
Query: 889 KWRPPERVGA--GGLDGYSVEYCPEGCS-EWVAALQGLTE--HTSILVKDL--------- 934
K R+ A G ++E+ +G E A L+ T+++ KD
Sbjct: 15169 KAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYT 15228
Query: 935 -----PTG-ARLLFRVRAHNMAG-PGAPVTTTEPVTVQEILQ-RPRLQLPRHLRQTIQKK 986
P G A+ +F V+ + G P P+ TE + + +L P L
Sbjct: 15229 LTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFPPLD-----------D 15277
Query: 987 VGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRN--SPTDTILFIRAARRVHSGTYQ 1044
G ++ I Q + ++ WT + ++ + + I + A + G
Sbjct: 15278 GGAKIDHYI-VQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYGVG--- 15333
Query: 1045 VTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQK 1104
E +E + L + P PP++ VT ++ + W P G +E+ Y V++
Sbjct: 15334 -----EPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVER 15388
Query: 1105 ADKKTMEWFTV-LEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTK-----EPV 1158
DK W + V L G+ Y FR+ ++N G S + T+ + V
Sbjct: 15389 RDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTV 15448
Query: 1159 FIPRPGITYEPPNYKALDFSEAP---SFTQPLVN-RSVIAGY 1196
F P P P N + LD S + ++ +P+ + S I GY
Sbjct: 15449 FKPGP-----PGNPRVLDTSRSSISIAWNKPIYDGGSEITGY 15485
Score = 85.5 bits (210), Expect = 3e-16
Identities = 66/214 (30%), Positives = 97/214 (45%), Gaps = 18/214 (8%)
Query: 1064 DKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVL-EHYRRT 1122
+KP P +T + + WKPP G ++ Y ++K +KK +W +V E R T
Sbjct: 24518 EKPGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRET 24577
Query: 1123 HCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPS 1182
V LI G Y FRV +N+ G S+ + + EP+ P+ + + P++K
Sbjct: 24578 VFSVKNLIEGLEYEFRVKCENLGGESEWSEIS-EPI-TPKSDVPIQAPHFK--------- 24626
Query: 1183 FTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDA---RFRMFSKQGVLTLE 1239
+ L N +V A L C V G PKP + W++ G ++ D R + F K G L
Sbjct: 24627 --EELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEF-KGGYHQLI 24683
Query: 1240 IRKPCPFDGGIYVCRATNLQGEARCECRLEVRVP 1273
I D +Y RATN G LEV VP
Sbjct: 24684 IASVTDDDATVYQVRATNQGGSVSGTASLEVEVP 24717
Score = 82.0 bits (201), Expect = 3e-15
Identities = 91/374 (24%), Positives = 142/374 (37%), Gaps = 41/374 (10%)
Query: 868 GPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHT 927
GPP+ P + ++++ T++++ W PPE G L GY VE W+ + +T T
Sbjct: 23528 GPPTGP--IKIDEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRST 23585
Query: 928 SILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKV 987
+ L G +FRV A N G G+ + + V E R+ P Q
Sbjct: 23586 FKFTR-LTEGNEYVFRVAATNRFGIGSYLQSE----VIECRSSIRIPGPPETLQIFDVSR 23640
Query: 988 GEPVNLLIPFQGKPRPQVTW--TKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQV 1045
P + QVT + + A V + P T+ R+ Y+
Sbjct: 23641 DGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPV-TMTRYRSTGLTEGLEYEH 23699
Query: 1046 TVRIENME--------DKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTEL 1097
V N K + + + P PQ+ RVTD +V+L W P+D G +++
Sbjct: 23700 RVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKV 23759
Query: 1098 WGYTVQKADKKTMEWF------TVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRA 1151
GY ++ EW T + Y TH +P+ G Y FRV + N G
Sbjct: 23760 TGYLIEMQKVDQHEWTKCNTTPTKIREYTLTH--LPQ---GAEYRFRVLACNAGG----- 23809
Query: 1152 ATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPK 1211
EP +P E Y + E + + + R G L ++G P P
Sbjct: 23810 --PGEPAEVPGTVKVTEMLEYPDYELDER--YQEGIFVRQ---GGVIRLTIPIKGKPFPI 23862
Query: 1212 ISWFKNGLDLGEDA 1225
W K G D+ + A
Sbjct: 23863 CKWTKEGQDISKRA 23876
Score = 81.3 bits (199), Expect = 6e-15
Identities = 69/301 (22%), Positives = 127/301 (42%), Gaps = 26/301 (8%)
Query: 367 KKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGS---KYIFESIGAKRTLTI 423
+ ++ QV + + + E+ + D + W K+G EI KY+ E + I
Sbjct: 3104 RSIKKEVQVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYVVER--RIHRMFI 3161
Query: 424 SQCSLADDAAYQCVVGGEKCSTELFVKEP-PVLITRPLEDQLVMVGQRVEFECEVS-EEG 481
S+ +D Y V G + S L+V P P + + L+ V G+ F +S
Sbjct: 3162 SETRQSDAGEYTFVAGRNRSSVTLYVNAPEPPQVLQELQPVTVQSGKPARFCAVISGRPQ 3221
Query: 482 AQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALA----- 536
++ W K+ E FK +F DGQ + L++ EA EDA Y +A
Sbjct: 3222 PKISWYKE--EQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSAS 3279
Query: 537 ------ELIVQEKKLEVYQS-----IADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELV 585
E++ ++++ VY + D + A F+C VS +++ W K++
Sbjct: 3280 LSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKKIK 3339
Query: 586 PDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPP 645
P +++ ++L I + P DE Y+FV +S+ + + +++ + RQ
Sbjct: 3340 PSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTAN-LSLEVQALDRQSSG 3398
Query: 646 K 646
K
Sbjct: 3399 K 3399
Score = 81.3 bits (199), Expect = 6e-15
Identities = 100/418 (23%), Positives = 150/418 (35%), Gaps = 61/418 (14%)
Query: 870 PSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSI 929
P P + + +VS +L W PP G + Y +E W + + +
Sbjct: 14168 PGPPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHV 14227
Query: 930 LVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGE 989
K L G +FRV A N G G PV + EPV + + P G
Sbjct: 14228 ATK-LIQGNEYIFRVSAVNHYGKGEPVQS-EPVKMVDRFGPP----------------GP 14269
Query: 990 PVNLLIPFQGKPRPQVTWTKE----GQPLAGEEVSIRNSPTDTILFIRAARRVHS----- 1040
P + K V+W + G + G V R + + ++RA + S
Sbjct: 14270 PEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKS--LRWVRAIKTPVSDLRCK 14327
Query: 1041 -------GTYQVTVRIENME--------DKATLVLQVVDKPSPPQDLRVTDAWGLNVALE 1085
TY+ V EN + L+ P PP + VTD + +L
Sbjct: 14328 VTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLA 14387
Query: 1086 WKPPQDVGNTELWGYTVQKADKKTMEWF--TVLEHYRRTHCVVPELIIGNGYYFRVFSQN 1143
W P G E+ GY V+ W T R T VVP+L Y FR+ + N
Sbjct: 14388 WGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAIN 14447
Query: 1144 MVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCA 1203
G EP IP I A DF + LV R AG + +
Sbjct: 14448 DAGVG-------EPAVIPDVEIVERE---MAPDFELDAELRRTLVVR---AGLSIRIFVP 14494
Query: 1204 VRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGE 1261
++G P P+++W K+ ++L A + + L I + +D G +V N G+
Sbjct: 14495 IKGRPAPEVTWTKDNINLKNRANIE--NTESFTLLIIPECNRYDTGKFVMTIENPAGK 14550
Score = 78.2 bits (191), Expect = 5e-14
Identities = 70/236 (29%), Positives = 112/236 (47%), Gaps = 14/236 (5%)
Query: 396 WLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVV---GGEKCST-ELFVKE 451
W+K+G I+ S K+ F + G R L I L+D Y CV+ EK ST +L V+E
Sbjct: 4846 WMKDGSNIRES-PKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEE 4904
Query: 452 PPVLITRPLEDQLVMV-GQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKKDGQRH 510
PV + LE+++ +V GQ + CE+++E V W KDG ++ E+ + G
Sbjct: 4905 LPVRFVKTLEEEVTVVKGQPLYLSCELNKE-RDVVWRKDG-KIVVEKPGRIVPGVIGLMR 4962
Query: 511 HLIINEAMLEDAGHYALCTSGGQAL----AELIVQEKKLEVYQSIADLMVGAKDQAVFKC 566
L IN+A DAG Y + L +V+ + + + I D V K A+F C
Sbjct: 4963 ALTINDADDTDAGTYTVTVENANNLECSSCVKVVEVIRDWLVKPIRDQHVKPKGTAIFAC 5022
Query: 567 EVSDENVRGVWLKNGKEL--VPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEG 620
+++ + W K E+ P+ + ++ G L I + P D A+Y+ EG
Sbjct: 5023 DIAKDTPNIKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEG 5078
Score = 77.8 bits (190), Expect = 6e-14
Identities = 98/433 (22%), Positives = 154/433 (35%), Gaps = 42/433 (9%)
Query: 847 YAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSV 906
Y + A S A+ + P P + + + L W PP G + Y V
Sbjct: 13061 YTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIV 13120
Query: 907 EYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQE 966
+ W A + TS V+ L G FR+ A N G G PV T EP +
Sbjct: 13121 DKRETSRPNW-AQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFT-EPAIAKN 13178
Query: 967 ILQRPRLQLPRHLRQTIQKKV-----------GEPVNLLIPFQGKPRPQVTWTKEGQ-PL 1014
P P + + + G P+ + + + V WTK + P+
Sbjct: 13179 PYDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYL-LEKRETQAVNWTKVNRKPI 13237
Query: 1015 AGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRV 1074
+ T R +G + + KA P PP +V
Sbjct: 13238 IERTLKATGLQEGTEYEFRVTAINKAGPGK-----PSDASKAAYARDPQYPPGPPAFPKV 13292
Query: 1075 TDAWGLNVALEWKPPQDVGNTELWGYTVQ--KADKKTMEWFTVLEHYRRTHCVVPELIIG 1132
D +V+L W P G + + GY V+ +AD + ++ ++T V L+
Sbjct: 13293 YDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMED 13352
Query: 1133 NGYYFRVFSQNMVGFSDRAATTKE----PVFIPRPGITYEPPNYKALDFSEAPSFTQPLV 1188
Y FRV++ N +G+SD + + + IP G LD + L+
Sbjct: 13353 TQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEG---------ELD----ADLRKTLI 13399
Query: 1189 NRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDG 1248
R AG T L V+G P PKI+W K ++L + + S L +D
Sbjct: 13400 LR---AGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDA 13456
Query: 1249 GIYVCRATNLQGE 1261
G Y+ N G+
Sbjct: 13457 GKYILTLENSCGK 13469
Score = 77.4 bits (189), Expect = 8e-14
Identities = 65/250 (26%), Positives = 112/250 (44%), Gaps = 8/250 (3%)
Query: 375 VSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAY 434
V++ + E+A+ D++ +WL++G+ + ++ + ES G KR L I+ L D Y
Sbjct: 2585 VAESQEAVFECEVANPDSKGEWLRDGKHLPLTNN-IRSESDGHKRRLIIAATKLDDIGEY 2643
Query: 435 QCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQ-VKWLKDGVEL 493
V K S +L V+ V I + L++ V Q F E++ + V+W+K+GV L
Sbjct: 2644 TYKVATSKTSAKLKVEA--VKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVL 2701
Query: 494 TREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIAD 553
E KY G + L I + D Y A A L V+ K + + D
Sbjct: 2702 ESNE--KYAISVKGTIYSLRIKNCAIVDESVYGFRLGRLGASARLHVETVK--IIKKPKD 2757
Query: 554 LMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEAD 613
+ F+ VS + V W E+ P + ++ +VHKL + +++P+D +
Sbjct: 2758 VTALENATVAFEVSVSHDTVPVKWFHKSVEIKPSDKHRLVSERKVHKLMLQNISPSDAGE 2817
Query: 614 YSFVPEGFAC 623
Y+ V C
Sbjct: 2818 YTAVVGQLEC 2827
Score = 77.4 bits (189), Expect = 8e-14
Identities = 52/242 (21%), Positives = 99/242 (40%), Gaps = 3/242 (1%)
Query: 374 QVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAA 433
+V + + + E++ +WLK QEI ++ G K ++ I + D+A
Sbjct: 5545 KVFEKDEAKFECEVSREPKTFRWLKGTQEIT-GDDRFELIKDGTKHSMVIKSAAFEDEAK 5603
Query: 434 YQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVEL 493
Y + S +L ++ + PL+D + F E+S + +VKW K+ L
Sbjct: 5604 YMFEAEDKHTSGKLIIEGIRLKFLTPLKDVTAKEKESAVFTVELSHDNIRVKWFKNDQRL 5663
Query: 494 TREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIAD 553
T + +G+ H + + ++D + G + A+L V E + D
Sbjct: 5664 --HTTRSVSMQDEGKTHSITFKDLSIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQD 5721
Query: 554 LMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEAD 613
KD+ + +CE+S + W K+GKE+ P + G+ L + +D
Sbjct: 5722 YTGVEKDEVILQCEISKADAPVKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQ 5781
Query: 614 YS 615
Y+
Sbjct: 5782 YT 5783
Score = 71.6 bits (174), Expect = 4e-12
Identities = 60/195 (30%), Positives = 92/195 (47%), Gaps = 17/195 (8%)
Query: 439 GGEKCSTEL----FVKEPPVLITRPLEDQLV----MVGQRVEFECEVSEEGAQVKWLKDG 490
GGEK E +K P+ + ++D ++ VG FEC VS A W+KDG
Sbjct: 4791 GGEKPPDEAPFTYQLKAVPLKFVKEIKDIILTESEFVGSSAIFECLVSPSTAITTWMKDG 4850
Query: 491 VELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQ----ALAELIVQEKKLE 546
+ E+ K+RF DG+ L I + L DAG Y G + A+L+V+E +
Sbjct: 4851 SNI--RESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEELPVR 4908
Query: 547 VYQSIADLMVGAKDQAVF-KCEVSDENVRGVWLKNGKELV-PDSRIKVSHIGRVHKLTID 604
+++ + + K Q ++ CE++ E VW K+GK +V RI IG + LTI+
Sbjct: 4909 FVKTLEEEVTVVKGQPLYLSCELNKER-DVVWRKDGKIVVEKPGRIVPGVIGLMRALTIN 4967
Query: 605 DVTPADEADYSFVPE 619
D D Y+ E
Sbjct: 4968 DADDTDAGTYTVTVE 4982
Score = 70.9 bits (172), Expect = 8e-12
Identities = 62/255 (24%), Positives = 106/255 (41%), Gaps = 6/255 (2%)
Query: 386 ELADHDAEVKWLKNGQEIQMS-GSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCS 444
++A +KW K EI K G L I D A Y + G++
Sbjct: 5023 DIAKDTPNIKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEGKRYP 5082
Query: 445 TELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFK 504
+L + E V + +P+ED + + F+ E+SE +W G L T + K
Sbjct: 5083 AKLTLGEREVELLKPIEDVTIYEKESASFDAEISEADIPGQWKLKGELLRPSPTCE--IK 5140
Query: 505 KDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVF 564
+G + L +++ L+ AG A L V+E +L+ + D+ V + QA F
Sbjct: 5141 AEGGKRFLTLHKVKLDQAGEVLYQALNAITTAILTVKEIELDFAVPLKDVTVPERRQARF 5200
Query: 565 KCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACN 624
+C ++ E +W K + + + G+ H L I+D DE Y+ EG
Sbjct: 5201 ECVLTRE-ANVIWSKGPDIIKSSDKFDIIADGKKHILVINDSQFDDEGVYTAEVEG--KK 5257
Query: 625 LSAKLHFMEVKIDFV 639
SA+L +++ F+
Sbjct: 5258 TSARLFVTGIRLKFM 5272
Score = 70.1 bits (170), Expect = 1e-11
Identities = 144/622 (23%), Positives = 227/622 (36%), Gaps = 79/622 (12%)
Query: 675 GDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRS 734
G P VI + +T K PA + TG ++ +KK L + T +
Sbjct: 18302 GRPEAIVITRNNVTLKWKKPAYDG--GSKITG----YIVEKKDLPDGRWMKASFTNVLET 18355
Query: 735 IFTVEGAEKEDEGVYTVTVKNPVG------EDQVNLTVK-VIDVPDAPAAPKISNVGEDS 787
FTV G ++ + V +N G + +T + ID P+A PK +V
Sbjct: 18356 EFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVH 18415
Query: 788 CTVQWEPPAYDGGQPILGYILERKKKKSYRWM-RLNF-DLIQELSHEARRMI--EGVVYE 843
+ A G+PI + + K+ R+ IQ+ + + I +G Y
Sbjct: 18416 AGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYI 18475
Query: 844 MRVYAVNAIGMSRPSPASQPFMPI-GPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLD 902
+++ + +G ++ P + + GPP P L V V+ L W PP + G +
Sbjct: 18476 LKL---SNVGGTKSIPITVKVLDRPGPPEGP--LKVTGVTAEKCYLAWNPPLQDGGANIS 18530
Query: 903 GYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPV 962
Y +E W + + K LP G +FRV A N G G P+ + PV
Sbjct: 18531 HYIIEKRETSRLSWTQVSTEVQALNYKVTKLLP-GNEYIFRVMAVNKYGIGEPLESG-PV 18588
Query: 963 TVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKE----GQPLAGEE 1018
T + P G P + K VTW + G + G
Sbjct: 18589 TACNPYKPP----------------GPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYI 18632
Query: 1019 VSIR----------NSPTDTILFIRAARRVHSGTYQVTVRIENME-----DKATLVLQVV 1063
+ R N T T L +R +Y+ V EN + ++ +
Sbjct: 18633 LEKRDKEGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRAC 18692
Query: 1064 DK---PSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEH-- 1118
D P PP + +VTD +V+L W P G + GY V+ + EW T
Sbjct: 18693 DALYPPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTG 18752
Query: 1119 YRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFS 1178
+ V +L Y FR+ + N G + A V R EPP + LD
Sbjct: 18753 LQGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQER----IEPPEIE-LD-- 18805
Query: 1179 EAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTL 1238
+ +V R A T L ++G P+P++ W K L + A+ + S +L +
Sbjct: 18806 --ADLRKVVVLR---ASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVI 18860
Query: 1239 EIRKPCPFDGGIYVCRATNLQG 1260
+ FD G Y N G
Sbjct: 18861 D--NVTRFDSGRYNLTLENNSG 18880
Score = 68.9 bits (167), Expect = 3e-11
Identities = 66/244 (27%), Positives = 95/244 (38%), Gaps = 30/244 (12%)
Query: 1034 AARRVHSGTYQVTVRIENME----------------DKATLVLQVVDKPSPPQDLRVTDA 1077
A + H TY+VT E E + T ++ + PSPP L + D
Sbjct: 14612 ATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDI 14671
Query: 1078 WGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYF 1137
V+L W P+ G +++ GY ++ K + +W T + + CVV L G Y F
Sbjct: 14672 TKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQW-THITTVKGLECVVRNLTEGEEYTF 14730
Query: 1138 RVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYT 1197
+V + N G R+A + RP I E LD Q LV AG
Sbjct: 14731 QVMAVNSAG---RSAPRES-----RPVIVKEQTMLPELDLR---GIYQKLVIAK--AGDN 14777
Query: 1198 AMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATN 1257
+ V G PKP ++W K L + R + L I + D G Y A N
Sbjct: 14778 IKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARN 14837
Query: 1258 LQGE 1261
+ GE
Sbjct: 14838 IVGE 14841
Score = 66.6 bits (161), Expect = 1e-10
Identities = 166/772 (21%), Positives = 275/772 (35%), Gaps = 163/772 (21%)
Query: 577 WLKNGKELVPD--SRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEV 634
W +G+++V D ++ + G L I TP+D +++ V + A S + +
Sbjct: 1444 WFHDGQQIVNDYTHKVVIKEDG-TQSLIIVPATPSDSGEWTVVAQNRAGRSSISVI---L 1499
Query: 635 KIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAP 694
++ V Q P + + G++L + V +G+P P ++W K
Sbjct: 1500 TVEAVEHQVKPMFVEKLKN-----VNIKEGSRLEMKVRATGNPNPDIVWLK--------- 1545
Query: 695 ARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVK 754
+SD V K ++R+E TK + ++ +D YT T
Sbjct: 1546 ------------NSDIIVPHKY------PKIRIEGTKGEAALKIDSTVSQDSAWYTATAI 1587
Query: 755 NPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKK 814
N G D V V V++ P +P I+ R
Sbjct: 1588 NKAGRDTTRCKVNV--------------------EVEFAEP-----EPERKLIIPRG--- 1619
Query: 815 SYRWMRLNFDLIQ--ELSHEARRMIEGVVYEMRVYA-------VNAIGMSRPSPASQP-- 863
+YR + ++ L + + EG +Y+ + ++ + R PA
Sbjct: 1620 TYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGPAHFECR 1679
Query: 864 FMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPE-GCSEWVAALQG 922
PIG P+ + D + + R G LD Y V Y + G A +
Sbjct: 1680 LTPIGDPTMVVEW-LHDGKPLEAANRLRMINEFGYCSLD-YGVAYSRDSGIITCRATNKY 1737
Query: 923 LTEHTS--ILVKD---------LPTGARLLFRVRA-HNMAGPGAPVTTTEPVTVQEILQR 970
T+HTS ++VKD LP G + L R+ MA GA T T Q+ Q+
Sbjct: 1738 GTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVT---TDQKEKQK 1794
Query: 971 PRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLA-GEEVSIRNSPTDTI 1029
P + L + ++ GE G P+P+V W GQ + + +R D I
Sbjct: 1795 PDIVL---YPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRY---DGI 1848
Query: 1030 LFIRAARRVHSGTYQVTVRIEN----MEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALE 1085
++ T +V V EN +E K L +Q +D R L A E
Sbjct: 1849 HYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQ------QREDFRSV----LRRAPE 1898
Query: 1086 WKPPQDVGNTELWGYTVQKADK-----KTMEWFTVLEHYRRTHCVVPELI---------- 1130
+P V + VQK D+ +T E + R TH VPE
Sbjct: 1899 PRPEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKVPEESEELRSKFKRR 1958
Query: 1131 IGNGYYFRV---------------------------FSQNMVGFSDRAATTKEPVFIPRP 1163
GYY + +++ + +A + + IP
Sbjct: 1959 TEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIP-- 2016
Query: 1164 GITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGE 1223
T++P + EAP + + +++V G A V G P P+ W+KNG+ +
Sbjct: 2017 --TFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIER 2074
Query: 1224 DAR-FRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVRVPQ 1274
R + + + V L IR D + +A N+ GE L V+ Q
Sbjct: 2075 SDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQ 2126
Score = 65.5 bits (158), Expect = 3e-10
Identities = 64/246 (26%), Positives = 101/246 (41%), Gaps = 35/246 (14%)
Query: 15 KPRSVEVAAGSPAVFEAETERAGVK-VRWQRGGSDISASNKYGLATEGTRHTLTVREVGP 73
KPRS+ V G A F +T+ V V W R G +S S ++ + T + T + V
Sbjct: 26261 KPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQA 26320
Query: 74 ADQGSYAVIA----GSSKVKFDLKVIEAEKAEPMLAPAPAPAEATGAPGEAPAPAAELGE 129
+D+G+Y+V+ G + +F L + +A E + P ++P P + E
Sbjct: 26321 SDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRV--------KSPEPRVKSPE 26372
Query: 130 SAPSPKGSSSAALNGPTPGAPDDPIGLFVMRPQDGEVTVGGSITFSAR------------ 177
+ SPK S + P +P + + Q V+ IT +
Sbjct: 26373 AVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPVSAPPKITQFLKAEASKEIAKLTC 26432
Query: 178 VAGASLLKPPVVKWFK-GKWVDLSSKVGQHLQLHDSYDRASKVYLFELHITDAQPAFTGS 236
V +S+L+ V W+K GK K H Q H S D +EL I + + G
Sbjct: 26433 VVESSVLRAKEVTWYKDGK----KLKENGHFQFHYSADGT-----YELKINNLTESDQGE 26483
Query: 237 YRCEVS 242
Y CE+S
Sbjct: 26484 YVCEIS 26489
Score = 63.5 bits (153), Expect = 1e-09
Identities = 102/453 (22%), Positives = 153/453 (33%), Gaps = 71/453 (15%)
Query: 820 RLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPAS-------QPFMPIGPPSE 872
R+N ++ L + + + VY V A S + A P +GP
Sbjct: 21697 RMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGP--- 21753
Query: 873 PTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVK 932
+ +++ ++L W P G + Y +E W A ++ E S
Sbjct: 21754 ---IRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAW-ALIEDKCEAQSYTAI 21809
Query: 933 DLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQ---EILQRPRLQLPRHLRQTI------ 983
L G FRV A N G G P+ + +PV Q + P + P ++
Sbjct: 21810 KLINGNEYQFRVSAVNKFGVGRPLDS-DPVVAQIQYTVPDAPGIPEPSNITGNSITLTWA 21868
Query: 984 --QKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSG 1041
+ G + I + + + W K I P F +
Sbjct: 21869 RPESDGGSEIQQYI-LERREKKSTRWVKV----------ISKRPISETRF-KVTGLTEGN 21916
Query: 1042 TYQVTVRIENME--------DKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVG 1093
Y+ V EN + + V+ P PP ++VTD V+LEW P G
Sbjct: 21917 EYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDG 21976
Query: 1094 NTELWGYTVQKADKKTMEWFTV-LEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAA 1152
E+ GY ++ +W V E +T V +L G Y FRV + N G D
Sbjct: 21977 GMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCE 22036
Query: 1153 TTKEPVFIPRPGITYEPPNYKALDFSEAP------SFTQPLVNRSVIAGYTAMLCCAVRG 1206
T KA+D AP +F Q V R AG + L A +G
Sbjct: 22037 VTG---------------TIKAVDRLTAPELDIDANFKQTHVVR---AGASIRLFIAYQG 22078
Query: 1207 SPKPKISWFKNGLDLGEDARFRMFSKQGVLTLE 1239
P P W K +L A LT+E
Sbjct: 22079 RPTPTAVWSKPDSNLSLRADIHTTDSFSTLTVE 22111
Score = 63.5 bits (153), Expect = 1e-09
Identities = 98/435 (22%), Positives = 159/435 (36%), Gaps = 53/435 (12%)
Query: 844 MRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDG 903
++ ++V + + RP P + P + V VS + L W P+ G +
Sbjct: 22423 VKTFSVTVVVIGRPGPVTGP------------IEVSSVSAESCVLSWGEPKDGGGTEITN 22470
Query: 904 YSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAG-----PGAPVTT 958
Y VE G + W + + T I V L FRV + N G AP+
Sbjct: 22471 YIVEKRESGTTAW-QLVNSSVKRTQIKVTHLTKYMEYSFRVSSENRFGVSKPLESAPIIA 22529
Query: 959 TEPVTVQEILQRPRLQLPRHLRQTI--QKKVGEPVNLLIPF--QGKPRPQVTWTKEGQPL 1014
P RP + +I ++ + + +I + + K R + W KE +
Sbjct: 22530 EHPFVPPSAPTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVP 22589
Query: 1015 AGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRV 1074
E T + + R ++ V + + + VD P P+ V
Sbjct: 22590 CLE---CNYKVTGLVEGLEYQFRTYA-LNAAGVSKASEASRPIMAQNPVDAPGRPE---V 22642
Query: 1075 TDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTM---EW----FTVLEHYRRTHCVVP 1127
TD V+L W P G +++ GY +++ + W +T++ T +
Sbjct: 22643 TDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALS 22702
Query: 1128 ELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPL 1187
E G+ Y FRV ++N G + + + PV Y PP + LD
Sbjct: 22703 E---GDTYEFRVLAKNAAGVISKGSESTGPVTCRDE---YAPPKAE-LDARLHGDLV--- 22752
Query: 1188 VNRSVIAGYTAMLCCAVRGSPKPKISWFKNG--LDLGEDARFRMFSKQGVLTLEIRKPCP 1245
++ AG +L AV G P+PKI W K LDL E + K+ T I+
Sbjct: 22753 ---TIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRA--TAVIKFCDR 22807
Query: 1246 FDGGIYVCRATNLQG 1260
D G Y N G
Sbjct: 22808 SDSGKYTLTVKNASG 22822
Score = 63.2 bits (152), Expect = 2e-09
Identities = 81/335 (24%), Positives = 134/335 (40%), Gaps = 41/335 (12%)
Query: 950 AGPG---APVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVT 1006
AGPG AP T+PV VQ++++ G V G P+P V
Sbjct: 1028 AGPGEPAAPYFITKPV-VQKLVE------------------GGSVVFGCQVGGNPKPHVY 1068
Query: 1007 WTKEGQPLAGE---EVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVV 1063
W K G PL +VS + L I +G Y + VR ++ E A+ L
Sbjct: 1069 WKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEE 1128
Query: 1064 DKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKK-TMEWFTVLEHYRRT 1122
+ + V + P+ VG T G+ + +K+ E + + +
Sbjct: 1129 ADYELLMKSQQEMLYQTQVTAFVQEPK-VGETAP-GFVYSEYEKEYEKEQALIRKKMAKD 1186
Query: 1123 HCVVPELIIGNGYYFRVFSQNMVGFSDRAA--TTKEPVFIPRPGITYEPPNYKALDFSEA 1180
VV + ++ F + ++ + TT E + + + A+D SE+
Sbjct: 1187 TVVVRTYVEDQEFHISSFEERLIKEIEYRIIKTTLEEL------LEEDGEEKMAVDISES 1240
Query: 1181 PS----FTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRM-FSKQGV 1235
+ F + N ++ G C + G P PKI+W+K+G + R++M F + G
Sbjct: 1241 EAVESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGR 1300
Query: 1236 LTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
+L I P D GIY A+N++G A C +L V
Sbjct: 1301 ASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYV 1335
Score = 62.4 bits (150), Expect = 3e-09
Identities = 65/275 (23%), Positives = 104/275 (37%), Gaps = 65/275 (23%)
Query: 1032 IRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQD 1091
++A +V G Y + ++N + P PP D+ V + + + WKPP
Sbjct: 8248 VKAVNKVGGGEY---IELKN----PVIAQDPKQPPDPPVDVEVHNPTAEAMTITWKPPLY 8300
Query: 1092 VGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELII-------GNGYYFRVFSQNM 1144
G +++ GY ++K K W EH +VP L G Y FRV ++N
Sbjct: 8301 DGGSKIMGYIIEKIAKGEERWKRCNEH------LVPILTYTAKGLEEGKEYQFRVRAENA 8354
Query: 1145 VGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAV 1204
G S+ + T P KA+D +AP + V G L ++
Sbjct: 8355 AGISEPSRAT---------------PPTKAVDPIDAPKVILR-TSLEVKRGDEIALDASI 8398
Query: 1205 RGSPKPKISWFKN-GLDLGEDARFRMF----------------------------SKQGV 1235
GSP P I+W K+ + + E+ + R SK+G
Sbjct: 8399 SGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGE 8458
Query: 1236 LTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
L +R D G+Y+ + N G A+ C + V
Sbjct: 8459 SQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSV 8493
Score = 60.5 bits (145), Expect = 1e-08
Identities = 55/197 (27%), Positives = 95/197 (48%), Gaps = 10/197 (5%)
Query: 451 EPPVLITRPLEDQLVMVGQRVEFECEV-SEEGAQVKWLKDGVELTREETFKYRFKKDGQR 509
E P + R ++ Q V G F V + + +W K+GV++ R + + + +D
Sbjct: 2030 EAPKIFER-IQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNV- 2087
Query: 510 HHLIINEAMLEDAGHY---ALCTSG-GQALAELIVQEKKLEVY-QSIADLMVGAKD-QAV 563
L+I + ED+ A+ +G + A L+VQ K+L + Q + D++ KD A
Sbjct: 2088 CELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMAT 2147
Query: 564 FKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFV-PEGFA 622
F+CE S+ V+ W K+G E+ + ++ +VH L+I + +D DYS V E
Sbjct: 2148 FECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDEN 2207
Query: 623 CNLSAKLHFMEVKIDFV 639
+AKL ++FV
Sbjct: 2208 VKTTAKLIVEGAVVEFV 2224
Score = 59.7 bits (143), Expect = 2e-08
Identities = 28/95 (29%), Positives = 46/95 (48%)
Query: 1176 DFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGV 1235
+ S+AP+F ++++ G + C + G P P+I WFKN L + + + + V
Sbjct: 26824 ELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNV 26883
Query: 1236 LTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
+LEIR D G Y +A N +G+ L V
Sbjct: 26884 YSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 26918
Score = 59.3 bits (142), Expect = 2e-08
Identities = 84/343 (24%), Positives = 125/343 (36%), Gaps = 68/343 (19%)
Query: 441 EKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEV-SEEGAQVKWLKDGVELTREETF 499
E S + F + IT + V GQ F V S+ A+VKW +GVEL +E+
Sbjct: 26056 EVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVEL--QESS 26113
Query: 500 KYRFKKDGQRHHLIINEAMLEDAGHY-ALCTS-GGQALAELIVQEKKLEVYQSIADLMVG 557
K + L I + +D+G Y A+CT+ G+A A L V
Sbjct: 26114 KIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEA--------------SDYATLDVT 26159
Query: 558 AKDQAVFKCEVSDENV-RGVWLKNGKELVPDSRIKVSHIGRVHKLTIDD--------VTP 608
D + + DE V R V+ EL VS + ++ +T
Sbjct: 26160 GGDYTTYASQRRDEEVPRSVF----PELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTE 26215
Query: 609 ADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRI---PDTIVVVAGN 665
E+ S+ A SA L ++ R KI RI P ++ V G
Sbjct: 26216 TRESLSSYEHSASAEMKSAALEEKSLEEKSTTR----KIKTTLAARILTKPRSMTVYEGE 26271
Query: 666 KLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRV 725
R G+P PTV W + K + T R
Sbjct: 26272 SARFSCDTDGEPVPTVTWLR-----------------------------KGQVLSTSARH 26302
Query: 726 RVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKV 768
+V TTK +S F + + DEG Y+V V+N G+ + T+ +
Sbjct: 26303 QVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTI 26345
Score = 58.9 bits (141), Expect = 3e-08
Identities = 168/856 (19%), Positives = 281/856 (32%), Gaps = 184/856 (21%)
Query: 17 RSVEVAAGSPAVFEAETERAGVKVRWQRGGSDIS--ASNKYGLATEGTRHTLTVREVGPA 74
+ V+V AV E E V W + G +I+ ++ E H + + E +
Sbjct: 3108 KEVQVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQS 3167
Query: 75 DQGSYAVIAGSSKVKFDLKVIEAE------KAEPMLAPAPAPAEATGAPGEAPAPAAE-- 126
D G Y +AG ++ L V E + +P+ + PA P P
Sbjct: 3168 DAGEYTFVAGRNRSSVTLYVNAPEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWY 3227
Query: 127 ------------------------LGESAPSPKG---------------SSSAALNGPTP 147
L E+ P S+S ++ P
Sbjct: 3228 KEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEV 3287
Query: 148 GAPDDPIGLF---VMRP-QDGEVTVGGSITFSARVAGASLLKPPVVKWFKGKWVDLSSKV 203
+PD + ++ ++ P QD + G F RV+G L V W+ S+
Sbjct: 3288 VSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDLK----VSWYSKDKKIKPSRF 3343
Query: 204 GQHLQLHDSYDRASKVYLFELHITDAQPAFTGSYRCEVSTKDKFDCSNFNLTVHEAMGTG 263
+ Q D+Y +L I +A P G+Y F SN V + T
Sbjct: 3344 FRMTQFEDTY---------QLEIAEAYPEDEGTYT--------FVASN---AVGQVSSTA 3383
Query: 264 DLDL-LSAFRRTSLAGGGRRISDSHEDTGILDFSSLLKKRDSFRTPRDSKLEAPAEEDVW 322
+L L + A R S G+ + +S + + D SS K+ + + E
Sbjct: 3384 NLSLEVQALDRQS---SGKDVRESAKSQAVAD-SSFTKEESKISQKEIKSFQGSSYEYEV 3439
Query: 323 EILRQAPPSEYERIAFQYGV-----TDLRGMLKRLKGMRRDEKKSTAFQKKLEPAYQ--- 374
++ S A L + + + + K+ST K+ Q
Sbjct: 3440 QVFESVSQSSIHTAASVQDTQLCHTASLSQIAESTELSKECAKESTGEAPKIFLHLQDVT 3499
Query: 375 VSKGHKIRLTVELADHD-AEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAA 433
V G + L D +V W G +I+ S + G + LTI L D
Sbjct: 3500 VKCGDTAQFLCVLKDDSFIDVTWTHEGAKIEES-ERLKQSQNGNIQFLTICNVQLVDQGL 3558
Query: 434 YQCVVG---GEKCSTELFVKE--PPVLITRPLEDQLVMVGQRVEFE---CEVSEEG---- 481
Y C+V GE+ ++ + E P ++ +E ++ M + EF EEG
Sbjct: 3559 YSCIVHNDCGERTTSAVLSVEGAPESILHERIEQEIEM--EMKEFSSSFLSAEEEGLHSA 3616
Query: 482 -AQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIV 540
Q+ + + +EL E Y K D ++ + + +
Sbjct: 3617 ELQLSKINETLELLSESPV-YPTKFDSEK-----------------------EGTGPIFI 3652
Query: 541 QEKKLEVYQSIADLMVGAKDQAVFKCEV-SDENVRGVWLKNGKELVPDSRIKVSHIGRVH 599
+E S AD+ +G D A V + W NG L P + K G H
Sbjct: 3653 KE------VSNADISMG--DVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDH 3704
Query: 600 KLTIDDVTPADEADYSFVPEG----FACNLSAKLH-----FMEVKIDFVPRQEPPKIHLD 650
L I DE +Y+ + C+ K++ + + + + K+
Sbjct: 3705 SLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGP 3764
Query: 651 CPGRIPDTIVVV---AGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGD 707
CP + + G + + G+PAPTV W K
Sbjct: 3765 CPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFK---------------------- 3802
Query: 708 SDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVK 767
+ K LC + + F V ++ED G+Y +N +GE +
Sbjct: 3803 ------ENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELL 3856
Query: 768 VI----DVPDAPAAPK 779
V+ D+ D P K
Sbjct: 3857 VLLEDTDMTDTPCKAK 3872
Score = 57.0 bits (136), Expect = 1e-07
Identities = 69/305 (22%), Positives = 116/305 (38%), Gaps = 26/305 (8%)
Query: 976 PRHLRQTIQKKVGEPVNLLIPFQ--GKPRPQVTWTKEGQPLA-GEEVSIRNSPTDTILFI 1032
P + Q + + E N+L + G+P P++ W K P++ VSI S L I
Sbjct: 26829 PAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEI 26888
Query: 1033 RAARRVHSGTYQVTVRIENMEDKAT---LVLQVVDKPSPPQDLRVTDAWGLNVALEWKPP 1089
R A SG Y + + + AT +VL +V++PS LR + L + +
Sbjct: 26889 RNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQGSFSSQSV 26948
Query: 1090 Q-DVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFS 1148
Q E + + +M ++ + E + + S + +G S
Sbjct: 26949 QMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFV------EMSSSSFMGIS 27002
Query: 1149 DRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSP 1208
+ + + GI PP +AL PS + S+ G + CA G P
Sbjct: 27003 NMTQLESSTSKMLKAGIRGIPPKIEAL-----PS------DISIDEGKVLTVACAFTGEP 27051
Query: 1209 KPKISWFKNG--LDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCEC 1266
P+++W G + E RF + + + TL I DGG+Y N G
Sbjct: 27052 TPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATV 27111
Query: 1267 RLEVR 1271
+ +R
Sbjct: 27112 NIHIR 27116
Score = 54.7 bits (130), Expect = 6e-07
Identities = 27/94 (28%), Positives = 44/94 (46%)
Query: 1181 PSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEI 1240
P+ L N +VI G + L C + G P P ++W++ + F++ + G+ L I
Sbjct: 897 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMI 956
Query: 1241 RKPCPFDGGIYVCRATNLQGEARCECRLEVRVPQ 1274
R+ D G + C A N G C L V+V +
Sbjct: 957 REAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSE 990
Score = 54.7 bits (130), Expect = 6e-07
Identities = 28/94 (29%), Positives = 45/94 (47%)
Query: 1180 APSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLE 1239
AP + + V G+ A C ++ +P + WFK G ++ E + + S + + +LE
Sbjct: 4528 APVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLE 4587
Query: 1240 IRKPCPFDGGIYVCRATNLQGEARCECRLEVRVP 1273
I + D G Y C+A+N G C L V VP
Sbjct: 4588 ILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVP 4621
Score = 54.7 bits (130), Expect = 6e-07
Identities = 24/85 (28%), Positives = 44/85 (51%)
Query: 12 FSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREV 71
F KP+++E+ G A F + V+W+R + + +KY + +G + L V++
Sbjct: 6249 FISKPQNLEILEGEKAEFVCSISKESFPVQWKRDDKTLESGDKYDVIADGKKRVLVVKDA 6308
Query: 72 GPADQGSYAVIAGSSKVKFDLKVIE 96
D G+Y V+ G+++ L VIE
Sbjct: 6309 TLQDMGTYVVMVGAARAAAHLTVIE 6333
Score = 54.3 bits (129), Expect = 7e-07
Identities = 31/96 (32%), Positives = 42/96 (43%)
Query: 1179 EAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTL 1238
E P Q L +V +G A C + G P+PKISW+K L + + TL
Sbjct: 3191 EPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTL 3250
Query: 1239 EIRKPCPFDGGIYVCRATNLQGEARCECRLEVRVPQ 1274
+ + P D +Y C A N G A L V VP+
Sbjct: 3251 LLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPE 3286
Score = 54.3 bits (129), Expect = 7e-07
Identities = 111/523 (21%), Positives = 174/523 (33%), Gaps = 88/523 (16%)
Query: 316 PAEEDVWEILRQAPPSEYERIAFQYGVTDLRGMLKRLKGMRRD-------EKKSTAFQKK 368
PAEE + R++P E R V+ R + + + R D K + QK
Sbjct: 25991 PAEEYEDDTERRSPTPERTRPRSPSPVSSERSLSRFERSARFDIFSRYESMKAALKTQKT 26050
Query: 369 LEPAYQV------SKGHKIRLTVELADH------------------DAEVKWLKNGQEIQ 404
E Y+V + H R+T+ + H AEVKW NG E+Q
Sbjct: 26051 SERKYEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQ 26110
Query: 405 MSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCSTELFV--------------- 449
S SK + + TL I C D Y+ V K +
Sbjct: 26111 ES-SKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQ 26169
Query: 450 ---KEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKKD 506
+E P + L + E+ E + V+ +K + TRE Y
Sbjct: 26170 RRDEEVPRSVFPELTRTEAYAVSSFKKTSEM-EASSSVREVKSQMTETRESLSSYEHSAS 26228
Query: 507 GQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFKC 566
+ + E LE+ + A ++ + + + VY+ + A F C
Sbjct: 26229 AEMKSAALEEKSLEEKSTTRKIKT--TLAARILTKPRSMTVYEG---------ESARFSC 26277
Query: 567 EVSDENVRGV-WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNL 625
+ E V V WL+ G+ L +R +V+ I V +DE +YS V E
Sbjct: 26278 DTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQ 26337
Query: 626 SA-------KLHFMEVKIDFVPRQEPPKIHLDCPGRI--PDTIVVVAGNKLRLDVPISGD 676
A K E + PR + P+ + P + P + + + P
Sbjct: 26338 EAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETK 26397
Query: 677 PAPT-------VIWQKAITQGNKAPARP-------APDAPEDTGDSDEWVFDKKLLCETE 722
P PT V ITQ KA A ++ W D K L E
Sbjct: 26398 PTPTEKVQHLPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKE-N 26456
Query: 723 GRVRVETTKDRSI-FTVEGAEKEDEGVYTVTVKNPVGEDQVNL 764
G + + D + + + D+G Y + G + NL
Sbjct: 26457 GHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNL 26499
Score = 53.1 bits (126), Expect = 2e-06
Identities = 31/104 (29%), Positives = 46/104 (44%)
Query: 1167 YEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDAR 1226
YE + + AP T + + V G V+ P ++ W+ NG++L E ++
Sbjct: 26055 YEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSK 26114
Query: 1227 FRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
+ GVLTLEI D G Y TN +GEA L+V
Sbjct: 26115 IHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDV 26158
Score = 52.8 bits (125), Expect = 2e-06
Identities = 28/90 (31%), Positives = 42/90 (46%)
Query: 6 KKPVSAFSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHT 65
K+P F+K V G+ AV E E R KV+W + G++I S KY + +G
Sbjct: 5976 KEPPVEFTKPLEDQTVEEGATAVLECEVSRENAKVKWFKNGTEILKSKKYEIVADGRVRK 6035
Query: 66 LTVREVGPADQGSYAVIAGSSKVKFDLKVI 95
L + + P D +Y A K +L V+
Sbjct: 6036 LVIHDCTPEDIKTYTCDAKDFKTSCNLNVV 6065
Score = 52.4 bits (124), Expect = 3e-06
Identities = 52/164 (31%), Positives = 74/164 (45%), Gaps = 17/164 (10%)
Query: 378 GHKIRLTVELADH-DAEVKWLKNGQEIQMSGS--KYIFESIGAKRTLTISQCSLADDAAY 434
G +R V + H + V W K+GQ+I+ + KY FES LTI+ + DDA Y
Sbjct: 25399 GENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEY 25458
Query: 435 QCVV----GGEKCSTELFV--KEPPVLIT-RPLEDQLV-----MVGQRVEFECEVSE-EG 481
V G + C +L V PP T RP+ +L+ GQ V FE VS
Sbjct: 25459 TVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPP 25518
Query: 482 AQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHY 525
+KW KDG L+ + + + L I + + ED G+Y
Sbjct: 25519 PTLKWEKDGQPLSLGPNIEI-IHEGLDYYALHIRDTLPEDTGYY 25561
Score = 52.0 bits (123), Expect = 4e-06
Identities = 26/86 (30%), Positives = 45/86 (52%)
Query: 14 KKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGP 73
+ P+ + A G+ VF AE + V+V+W R + +K+ + +EG H L + ++ P
Sbjct: 6611 RPPQDILEAPGADVVFLAELNKDKVEVQWLRNNMVVVQGDKHQMMSEGKIHRLQICDIKP 6670
Query: 74 ADQGSYAVIAGSSKVKFDLKVIEAEK 99
DQG Y IA + + L++ A K
Sbjct: 6671 RDQGEYRFIAKDKEARAKLELAAAPK 6696
Score = 50.8 bits (120), Expect = 8e-06
Identities = 51/207 (24%), Positives = 78/207 (37%), Gaps = 17/207 (8%)
Query: 1055 KATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGY-TVQKADKKTMEWF 1113
K L + +P PP+ L VT+ + L W PP G ++ GY T + +++ + +
Sbjct: 12483 KPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRW 12542
Query: 1114 TVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYK 1173
T + VV L G Y FRV ++N VG S +PR Y+
Sbjct: 12543 TEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVS-----------LPREAEGV----YE 12587
Query: 1174 ALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQ 1233
A + P P ++ AG + V G P P W K ++ + +
Sbjct: 12588 AKEQLLPPKILMP-EQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKAD 12646
Query: 1234 GVLTLEIRKPCPFDGGIYVCRATNLQG 1260
L I+ D G Y A N G
Sbjct: 12647 SSSILIIKDVTRKDSGYYSLTAENSSG 12673
Score = 50.4 bits (119), Expect = 1e-05
Identities = 22/81 (27%), Positives = 39/81 (48%)
Query: 17 RSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQ 76
+ +E F + R V ++W + G ++ N+ + +H LT+++ G D+
Sbjct: 6436 KDIETMEKKSVTFWCKVNRLNVTLKWTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGFPDE 6495
Query: 77 GSYAVIAGSSKVKFDLKVIEA 97
G Y V AG K +L +IEA
Sbjct: 6496 GEYIVTAGQDKSVAELLIIEA 6516
Score = 50.1 bits (118), Expect = 1e-05
Identities = 53/164 (32%), Positives = 80/164 (48%), Gaps = 20/164 (12%)
Query: 393 EVKWLKNGQEIQMS---GSKYIFESIGAKRTLTISQCSLADDAAYQCVV---GGEKCST- 445
EV W ++GQ I S G + F AK LTI + A+ Y G+ ST
Sbjct: 36 EVSWFRDGQVISTSTLPGVQISFSDGRAK--LTIPAVTKANSGRYSLKATNGSGQATSTA 93
Query: 446 ELFVKE---PPVLITRPLEDQLVMVGQRVEFECEVSEEGAQV-KWLKDGVELTREETFKY 501
EL VK PP + R L+ V G +V + V+ V K+ +DG E+ + + +
Sbjct: 94 ELLVKAETAPPNFVQR-LQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEI--QSSLDF 150
Query: 502 RFKKDGQRHHLIINEAMLEDAGHYAL--CTSGGQA--LAELIVQ 541
+ ++G + L+I EA ED+G Y++ S G+A AEL+VQ
Sbjct: 151 QISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194
Score = 49.7 bits (117), Expect = 2e-05
Identities = 54/228 (23%), Positives = 83/228 (36%), Gaps = 35/228 (15%)
Query: 1058 LVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLE 1117
L + + P+ P+ L T+ + L+WK P+ G + + GY ++K ++ E
Sbjct: 8982 LAVDPLGPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDF----E 9037
Query: 1118 HYRRTHCVVPELIIGN-----GYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNY 1172
+ C ++ N Y FRV + N +G S+ + P N
Sbjct: 9038 RVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSL----------------PLNV 9081
Query: 1173 KALDFSEAPSFTQPLVNRS----VIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFR 1228
D P+ L R V AG + V G P PKI W KN + +
Sbjct: 9082 VIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDAL 9141
Query: 1229 MFSKQGV------LTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
+K+ V L I K D G Y A+N G +EV
Sbjct: 9142 QITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEV 9189
Score = 49.7 bits (117), Expect = 2e-05
Identities = 24/94 (25%), Positives = 40/94 (42%)
Query: 1178 SEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLT 1237
S P L + +V + A G P+P W K+G + + ++++ +G
Sbjct: 26544 SSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFF 26603
Query: 1238 LEIRKPCPFDGGIYVCRATNLQGEARCECRLEVR 1271
LEI K D G+Y C N G C+L ++
Sbjct: 26604 LEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIK 26637
Score = 48.5 bits (114), Expect = 4e-05
Identities = 24/81 (29%), Positives = 37/81 (45%)
Query: 14 KKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGP 73
KKP+ V + FE V V+W +I S+K+ L +E H L ++ + P
Sbjct: 2753 KKPKDVTALENATVAFEVSVSHDTVPVKWFHKSVEIKPSDKHRLVSERKVHKLMLQNISP 2812
Query: 74 ADQGSYAVIAGSSKVKFDLKV 94
+D G Y + G + K L V
Sbjct: 2813 SDAGEYTAVVGQLECKAKLFV 2833
Score = 48.1 bits (113), Expect = 5e-05
Identities = 30/96 (31%), Positives = 47/96 (48%), Gaps = 2/96 (2%)
Query: 1178 SEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDA--RFRMFSKQGV 1235
++AP+FTQPL + V+ G TA + G P P++SWF++G + ++ G
Sbjct: 3 TQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGR 62
Query: 1236 LTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVR 1271
L I + G Y +ATN G+A L V+
Sbjct: 63 AKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98
Score = 48.1 bits (113), Expect = 5e-05
Identities = 54/233 (23%), Positives = 91/233 (39%), Gaps = 50/233 (21%)
Query: 545 LEVYQSIADLMVGAKD----QAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHK 600
L+ + I D+++ + A+F+C VS W+K+G + + + G+ K
Sbjct: 4810 LKFVKEIKDIILTESEFVGSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIADGKDRK 4869
Query: 601 LTIDDVTPADEADYSFVPE--GFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDT 658
L I DV +D +Y+ V +AKL E+ + FV E +
Sbjct: 4870 LHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEELPVRFVKTLE-------------EE 4916
Query: 659 IVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLL 718
+ VV G L L ++ + V+W+K D K++
Sbjct: 4917 VTVVKGQPLYLSCELNKE--RDVVWRK----------------------------DGKIV 4946
Query: 719 CETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDV 771
E GR+ T+ A+ D G YTVTV+N + + VKV++V
Sbjct: 4947 VEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVEN-ANNLECSSCVKVVEV 4998
Score = 47.8 bits (112), Expect = 7e-05
Identities = 31/102 (30%), Positives = 44/102 (43%)
Query: 1169 PPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFR 1228
P + + P F + + N + G A L V G PKPKI WF NG+ L A ++
Sbjct: 3637 PTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYK 3696
Query: 1229 MFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
+L I D G Y C A+N G+ C L++
Sbjct: 3697 FVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKI 3738
Score = 47.8 bits (112), Expect = 7e-05
Identities = 26/93 (27%), Positives = 41/93 (44%), Gaps = 3/93 (3%)
Query: 1181 PSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDL---GEDARFRMFSKQGVLT 1237
P FT PL N++ G + P+P ++W+K+G + D ++ S +G+
Sbjct: 25385 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQ 25444
Query: 1238 LEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
L I D Y A N GE C+ +L V
Sbjct: 25445 LTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV 25477
Score = 47.0 bits (110), Expect = 1e-04
Identities = 27/91 (29%), Positives = 40/91 (43%), Gaps = 1/91 (1%)
Query: 1181 PSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMF-SKQGVLTLE 1239
P F + L G A+ V G P P ++WFK L + + + G T
Sbjct: 3767 PHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFI 3826
Query: 1240 IRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
+ P D G+Y+C+A N+ GE+ C L V
Sbjct: 3827 VNDPQREDSGLYICKAENMLGESTCAAELLV 3857
Score = 45.8 bits (107), Expect = 3e-04
Identities = 22/82 (26%), Positives = 35/82 (42%)
Query: 13 SKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVG 72
+K +++EV A FE E V W + G +I S K+ + +G H L +
Sbjct: 2839 TKTMKNIEVPETKTASFECEVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTS 2898
Query: 73 PADQGSYAVIAGSSKVKFDLKV 94
D Y + G+ +V L V
Sbjct: 2899 TEDSAEYTFVCGNDQVSATLTV 2920
Score = 45.1 bits (105), Expect = 4e-04
Identities = 27/80 (33%), Positives = 37/80 (46%)
Query: 17 RSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQ 76
+ V V AG A F+ E + V W G + S+K +EG HTLT+R+V D
Sbjct: 5898 KDVTVTAGETATFDCELSYEDIPVEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLEDA 5957
Query: 77 GSYAVIAGSSKVKFDLKVIE 96
G + A K +L V E
Sbjct: 5958 GEVQLTAKDFKTHANLFVKE 5977
Score = 45.1 bits (105), Expect = 4e-04
Identities = 29/91 (31%), Positives = 44/91 (48%), Gaps = 5/91 (5%)
Query: 1183 FTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRK 1242
FT+PL +++V G TA+L C V K+ WFKNG ++ + ++ + + V L I
Sbjct: 5982 FTKPLEDQTVEEGATAVLECEV-SRENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHD 6040
Query: 1243 PCPFDGGIYVCRATNLQGEARCECRLEVRVP 1273
P D Y C A + + C L V P
Sbjct: 6041 CTPEDIKTYTCDAKDF----KTSCNLNVVPP 6067
Score = 44.7 bits (104), Expect = 6e-04
Identities = 33/108 (30%), Positives = 43/108 (39%), Gaps = 6/108 (5%)
Query: 1165 ITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNG--LDLG 1222
+T PP D + P F + L N G + V G P P + W K+G L LG
Sbjct: 25477 VTLHPP---PTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLG 25533
Query: 1223 EDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
+ + L IR P D G Y ATN G C+ L+V
Sbjct: 25534 PNIEI-IHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQV 25580
Score = 44.7 bits (104), Expect = 6e-04
Identities = 48/223 (21%), Positives = 85/223 (38%), Gaps = 8/223 (3%)
Query: 558 AKDQAVFKCEVSDENVRG---VWLKNGKELVPDSRIKVSHIGR-VHKLTIDDVTPADEAD 613
+K+ A C V +R W K+GK+L + + + ++L I+++T +D+ +
Sbjct: 26424 SKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGE 26483
Query: 614 YSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPI 673
Y G L FM + + + V + + PI
Sbjct: 26484 YVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPI 26543
Query: 674 SGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDR 733
S P V + T + + A+ A A + + W D K + + G+ ++ K
Sbjct: 26544 SSKPV-IVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQG-GKYKLSEDKGG 26601
Query: 734 SIFTVEGAEKEDEGVYTVTVKNPVG--EDQVNLTVKVIDVPDA 774
+ + D G+YT TVKN G LT+K I +A
Sbjct: 26602 FFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEA 26644
Score = 44.3 bits (103), Expect = 8e-04
Identities = 26/91 (28%), Positives = 43/91 (47%)
Query: 1181 PSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEI 1240
P+F Q L + +V G L V G P P + ++++G ++ F++ + + +L I
Sbjct: 104 PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLI 163
Query: 1241 RKPCPFDGGIYVCRATNLQGEARCECRLEVR 1271
+ P D G Y ATN G A L V+
Sbjct: 164 AEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194
Score = 44.3 bits (103), Expect = 8e-04
Identities = 29/108 (26%), Positives = 49/108 (45%), Gaps = 16/108 (14%)
Query: 10 SAFSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVR 69
+ F+K ++EV+ E + G +V W +G +I + +Y + TEG + L ++
Sbjct: 6158 AVFTKNLANIEVSETDTIKLVCEVSKPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQ 6217
Query: 70 EVGPADQGSYAVIAGSS----KVKF------------DLKVIEAEKAE 101
D G+Y SS KVK +L+++E EKAE
Sbjct: 6218 NAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLEILEGEKAE 6265
Score = 43.5 bits (101), Expect = 0.001
Identities = 23/76 (30%), Positives = 35/76 (46%)
Query: 28 VFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYAVIAGSSK 87
VFE E +G+ V W +I S+KY + G + LTV + D+G Y AG +
Sbjct: 2505 VFEVELSHSGIDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTFYAGENM 2564
Query: 88 VKFDLKVIEAEKAEPM 103
L V ++P+
Sbjct: 2565 TSGKLTVAGGAISKPL 2580
Score = 43.1 bits (100), Expect = 0.002
Identities = 45/174 (25%), Positives = 72/174 (41%), Gaps = 10/174 (5%)
Query: 449 VKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKKDGQ 508
+KE +I PL D + G V ++ +V W + + +E FK +D
Sbjct: 4430 IKEDGPMIHTPLVDTVSEEGDIVHLTTSITN-AKEVNWYFENKLVPSDEKFKCL--QDQN 4486
Query: 509 RHHLIINEAMLED-AGHY---ALCTSGGQALAELIVQEKKLE--VYQSIADLMVGAKDQA 562
+ L+I++ ED G Y AL SG A + + K+ + + I L V A
Sbjct: 4487 TYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLA 4546
Query: 563 VFKCEV-SDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYS 615
F CE+ S NVR W K G+E+ + + + L I D +Y+
Sbjct: 4547 KFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYT 4600
Score = 42.0 bits (97), Expect = 0.004
Identities = 33/111 (29%), Positives = 51/111 (45%), Gaps = 14/111 (12%)
Query: 453 PVLITRPLEDQLVMVGQRVEFECEVS-EEGAQVKWLKDGVELTREETFKYRFKKDGQRHH 511
P IT+P+ +LV G V F C+V V W K GV LT +K + K
Sbjct: 1036 PYFITKPVVQKLVEGGS-VVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECK 1094
Query: 512 LIINEAMLEDAGHYALC-------TSGGQALA-----ELIVQEKKLEVYQS 550
L+I+ +DAG Y + TS +L EL+++ ++ +YQ+
Sbjct: 1095 LVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLMKSQQEMLYQT 1145
Score = 41.6 bits (96), Expect = 0.005
Identities = 21/86 (24%), Positives = 38/86 (44%)
Query: 9 VSAFSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTV 68
V F K+ + +EV E ++ +W ++ ++ KY + + R LTV
Sbjct: 2220 VVEFVKELQDIEVPESYSGELECIVSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTV 2279
Query: 69 REVGPADQGSYAVIAGSSKVKFDLKV 94
++V DQG Y+ + K LK+
Sbjct: 2280 KDVTKEDQGEYSFVIDGKKTTCKLKM 2305
Score = 41.2 bits (95), Expect = 0.006
Identities = 23/105 (21%), Positives = 46/105 (43%), Gaps = 16/105 (15%)
Query: 12 FSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREV 71
F K + ++V A+FE E + V+W + ++ +++ + E H L +
Sbjct: 3014 FRKHIKDIKVLEKKRAMFECEVSEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPST 3073
Query: 72 GPADQGSYAVIAGSS----------------KVKFDLKVIEAEKA 100
+D G Y V+AG + +K +++VIE ++A
Sbjct: 3074 RMSDAGKYTVVAGGNVSTAKLFVEGRDVRIRSIKKEVQVIEKQRA 3118
Score = 41.2 bits (95), Expect = 0.006
Identities = 23/91 (25%), Positives = 41/91 (45%)
Query: 8 PVSAFSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLT 67
P F + ++V A FE E R KV+W + G++I KY + ++G L
Sbjct: 6067 PHVEFLRPLTDLQVREKEMARFECELSRENAKVKWFKDGAEIKKGKKYDIISKGAVRILV 6126
Query: 68 VREVGPADQGSYAVIAGSSKVKFDLKVIEAE 98
+ + D+ Y+ +++ L V+E E
Sbjct: 6127 INKCLLDDEAEYSCEVRTARTSGMLTVLEEE 6157
Score = 40.8 bits (94), Expect = 0.008
Identities = 38/167 (22%), Positives = 69/167 (41%), Gaps = 8/167 (4%)
Query: 457 TRPLEDQLVMVGQRVEFECEVSE-EGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIIN 515
T+PL+ +V+ G FE +S +V W +DG ++ + R L I
Sbjct: 9 TQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIP 68
Query: 516 EAMLEDAGHYALCTSGGQ----ALAELIVQEKKL--EVYQSIADLMVGAKDQAVFKCEVS 569
++G Y+L + G + AEL+V+ + Q + + V Q + V+
Sbjct: 69 AVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVT 128
Query: 570 DENVRGV-WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYS 615
V + ++G E+ ++S G ++ L I + P D YS
Sbjct: 129 GIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYS 175
Score = 40.8 bits (94), Expect = 0.008
Identities = 21/70 (30%), Positives = 36/70 (51%), Gaps = 1/70 (1%)
Query: 27 AVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYA-VIAGS 85
A FE ET VKV+W + G ++ +KY + ++ H L++ + +D Y+ V+
Sbjct: 2146 ATFECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVED 2205
Query: 86 SKVKFDLKVI 95
VK K+I
Sbjct: 2206 ENVKTTAKLI 2215
Score = 40.8 bits (94), Expect = 0.008
Identities = 29/105 (27%), Positives = 44/105 (41%), Gaps = 9/105 (8%)
Query: 27 AVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYA--VIAG 84
AVF + R V+W R G +I KY +G+ H L +++ D+ YA V
Sbjct: 6535 AVFSCQLSREKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDCRLDDECEYACGVEDR 6594
Query: 85 SSKVKFDLKVIEAEKAEPMLAPAPAPAEATGAPGEAPAPAAELGE 129
S+ + ++ I E P P + APG AEL +
Sbjct: 6595 KSRARLFVEEIPVEIIRP-------PQDILEAPGADVVFLAELNK 6632
Score = 40.8 bits (94), Expect = 0.008
Identities = 24/80 (30%), Positives = 38/80 (47%), Gaps = 1/80 (1%)
Query: 40 VRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYAVIAGSSKVKFDLKVIEAEK 99
++W R G ++ S KY ++++G HTLTV D+G Y IA + + + +
Sbjct: 24259 IKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQ 24318
Query: 100 AEPMLAPA-PAPAEATGAPG 118
A P P P + GA G
Sbjct: 24319 ATPQFHPGYPLKEKYYGAVG 24338
Score = 40.8 bits (94), Expect = 0.008
Identities = 69/326 (21%), Positives = 130/326 (39%), Gaps = 64/326 (19%)
Query: 478 SEEGAQVKWLKDGVELTREE---TFKYR------FKKDGQRHHLIINEAMLEDAGHYALC 528
+ E Q WLK +E + T K+R KKD +++++ A + G A+
Sbjct: 25191 ASEALQHPWLKQKIERVSTKVIRTLKHRRYYHTLIKKD---LNMVVSAARISCGG--AIR 25245
Query: 529 TSGGQALAELIVQEKKL-----EVYQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKE 583
+ G ++A++ V ++ ++ ++ + G + V K E D++ + W ++
Sbjct: 25246 SQKGVSVAKVKVASIEIGPVSGQIMHAVGE--EGGHVKYVCKIENYDQSTQVTWYFGVRQ 25303
Query: 584 LVPDSRIKVSHIGRVHKLTIDDVTPADEADY--SFVPEGFACNLSAKLHFMEVK--IDFV 639
L + ++++ V L + D+T D+ Y V + + A+L V+ D+
Sbjct: 25304 LENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFVKGVREVYDYY 25363
Query: 640 PRQEPPKIH--------LDCPGRIPDTI---VVVAGNKLRLDVPISGDPAPTVIWQKAIT 688
R+ KI L+ P + G +R V I+ P P V W K+
Sbjct: 25364 CRRTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKS-- 25421
Query: 689 QGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGV 748
G K +P + + T +SD+ ++ T+ +D+
Sbjct: 25422 -GQKI--KPGDNDKKYTFESDKGLYQ---------------------LTINSVTTDDDAE 25457
Query: 749 YTVTVKNPVGED--QVNLTVKVIDVP 772
YTV +N GED + LTV + P
Sbjct: 25458 YTVVARNKYGEDSCKAKLTVTLHPPP 25483
Score = 40.4 bits (93), Expect = 0.011
Identities = 18/57 (31%), Positives = 30/57 (52%)
Query: 38 VKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYAVIAGSSKVKFDLKV 94
V V+W + G +I S KY + +G R L +++ D+G Y G+ K K ++ V
Sbjct: 5385 VPVKWFKDGEEIVPSPKYSIKADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTV 5441
Score = 40.4 bits (93), Expect = 0.011
Identities = 17/61 (27%), Positives = 31/61 (50%)
Query: 19 VEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGS 78
V+V A FE E R RW +G +I+ +++ L +GT+H++ ++ D+
Sbjct: 5544 VKVFEKDEAKFECEVSREPKTFRWLKGTQEITGDDRFELIKDGTKHSMVIKSAAFEDEAK 5603
Query: 79 Y 79
Y
Sbjct: 5604 Y 5604
Score = 39.7 bits (91), Expect = 0.019
Identities = 46/199 (23%), Positives = 87/199 (43%), Gaps = 20/199 (10%)
Query: 453 PVLITRPLEDQLVMVGQRVEFECEV-SEEGAQVKWLKDGVELTREETFKYRFKKDGQRHH 511
PV + +P+ + + GQ F+ +V + W DG ++ + T K K+DG +
Sbjct: 1411 PVFVLKPVSFKC-LEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQ-S 1468
Query: 512 LIINEAMLEDAGHYALCT---SGGQALAELI-VQEKKLEVYQSIADLM--VGAKDQAVFK 565
LII A D+G + + +G +++ ++ V+ + +V + + V K+ + +
Sbjct: 1469 LIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLE 1528
Query: 566 CEV---SDENVRGVWLKNGKELVPDS--RIKVSHIGRVHKLTIDDVTPADEADYSFVPEG 620
+V + N VWLKN +VP +I++ L ID D A Y+
Sbjct: 1529 MKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAIN 1588
Query: 621 FA------CNLSAKLHFME 633
A C ++ ++ F E
Sbjct: 1589 KAGRDTTRCKVNVEVEFAE 1607
Score = 39.7 bits (91), Expect = 0.019
Identities = 26/92 (28%), Positives = 37/92 (40%), Gaps = 1/92 (1%)
Query: 1181 PSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEI 1240
P+ PL + G A C V G+ K+SW+ + FRM + LEI
Sbjct: 3299 PAIITPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEI 3357
Query: 1241 RKPCPFDGGIYVCRATNLQGEARCECRLEVRV 1272
+ P D G Y A+N G+ L + V
Sbjct: 3358 AEAYPEDEGTYTFVASNAVGQVSSTANLSLEV 3389
Score = 39.3 bits (90), Expect = 0.024
Identities = 29/94 (30%), Positives = 37/94 (39%), Gaps = 1/94 (1%)
Query: 11 AFSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVRE 70
A SK VA AVFE E K W R G + +N ++G + L +
Sbjct: 2575 AISKPLTDQTVAESQEAVFECEVANPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAA 2634
Query: 71 VGPADQGSYAVIAGSSKVKFDLKVIEAEKAEPML 104
D G Y +SK LKV EA K + L
Sbjct: 2635 TKLDDIGEYTYKVATSKTSAKLKV-EAVKIKKTL 2667
Score = 39.3 bits (90), Expect = 0.024
Identities = 22/88 (25%), Positives = 41/88 (46%), Gaps = 16/88 (18%)
Query: 29 FEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYAVIAGSS-- 86
FE G+ +W + G +I +++K + T+ H+L +R V D Y +AG +
Sbjct: 2942 FEVTVNYEGISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKATS 3001
Query: 87 ---------KVKF-----DLKVIEAEKA 100
++F D+KV+E ++A
Sbjct: 3002 TATLYVEARHIEFRKHIKDIKVLEKKRA 3029
Score = 38.5 bits (88), Expect = 0.041
Identities = 22/81 (27%), Positives = 35/81 (43%)
Query: 1191 SVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGI 1250
+V G +A C G P P ++W + G L AR ++ + + T EI D G
Sbjct: 26266 TVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGN 26325
Query: 1251 YVCRATNLQGEARCECRLEVR 1271
Y N +G+ E L ++
Sbjct: 26326 YSVVVENSEGKQEAEFTLTIQ 26346
Score = 37.7 bits (86), Expect = 0.071
Identities = 30/109 (27%), Positives = 43/109 (39%), Gaps = 1/109 (0%)
Query: 1163 PGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLG 1222
PG E + L+ P F V+ + G TA V G P P+ WF +G +
Sbjct: 1393 PGRRLEETDESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIV 1452
Query: 1223 EDARFRMFSKQ-GVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
D ++ K+ G +L I P D G + A N G + L V
Sbjct: 1453 NDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTV 1501
Score = 36.6 bits (83), Expect = 0.16
Identities = 20/71 (28%), Positives = 33/71 (46%), Gaps = 3/71 (4%)
Query: 456 ITRPLEDQLVMVGQRVEFECE-VSEEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLII 514
I + ++D +G+ + C+ V +KW + G EL + KY+ DG+ H L +
Sbjct: 24230 IRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSR--KYKMSSDGRTHTLTV 24287
Query: 515 NEAMLEDAGHY 525
ED G Y
Sbjct: 24288 MTEEQEDEGVY 24298
Score = 36.6 bits (83), Expect = 0.16
Identities = 27/92 (29%), Positives = 42/92 (45%), Gaps = 5/92 (5%)
Query: 1175 LDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSP--KPKISWFKNGLDLGEDARFRM-FS 1231
L S P TQ L ++ + A L C V S +++W+K+G L E+ F+ +S
Sbjct: 26407 LPVSAPPKITQFL--KAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYS 26464
Query: 1232 KQGVLTLEIRKPCPFDGGIYVCRATNLQGEAR 1263
G L+I D G YVC + G ++
Sbjct: 26465 ADGTYELKINNLTESDQGEYVCEISGEGGTSK 26496
Score = 36.2 bits (82), Expect = 0.21
Identities = 20/79 (25%), Positives = 34/79 (43%), Gaps = 1/79 (1%)
Query: 17 RSVEVAAGSPAVFEAETERAGV-KVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPAD 75
+ V V G+ AV E + V V+W I ++ +GT+ L + +D
Sbjct: 2406 KDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHASD 2465
Query: 76 QGSYAVIAGSSKVKFDLKV 94
+G Y +I G + +L V
Sbjct: 2466 EGPYKLIVGRVETNCNLSV 2484
Score = 35.8 bits (81), Expect = 0.27
Identities = 19/72 (26%), Positives = 35/72 (48%), Gaps = 1/72 (1%)
Query: 14 KKPRSVEVAAGSPAVFEAETERAGVK-VRWQRGGSDISASNKYGLATEGTRHTLTVREVG 72
K +++ V AVF E VK V+W + G + ++ KY ++ +GT ++L ++
Sbjct: 2665 KTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYSLRIKNCA 2724
Query: 73 PADQGSYAVIAG 84
D+ Y G
Sbjct: 2725 IVDESVYGFRLG 2736
Score = 35.8 bits (81), Expect = 0.27
Identities = 23/78 (29%), Positives = 35/78 (44%)
Query: 19 VEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGS 78
VEV G A FE E V +W+ G ++AS + +G +H L + G
Sbjct: 5455 VEVFVGETAHFEIELSEPDVHGQWKLKGQPLTASPDCEIIEDGKKHILILHNCQLGMTGE 5514
Query: 79 YAVIAGSSKVKFDLKVIE 96
+ A ++K +LKV E
Sbjct: 5515 VSFQAANAKSAANLKVKE 5532
Score = 35.8 bits (81), Expect = 0.27
Identities = 18/78 (23%), Positives = 36/78 (46%), Gaps = 2/78 (2%)
Query: 28 VFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYAVIAGSSK 87
+ + E +A V+W + G +I S + +G + L +++ +D G Y G+ K
Sbjct: 5731 ILQCEISKADAPVKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTCDCGTDK 5790
Query: 88 V--KFDLKVIEAEKAEPM 103
K D++ E + P+
Sbjct: 5791 TSGKLDIEDREIKLVRPL 5808
Score = 35.8 bits (81), Expect = 0.27
Identities = 27/118 (22%), Positives = 50/118 (42%), Gaps = 19/118 (16%)
Query: 577 WLKNGKELVP---DSRIKVSHIGRVHKLTIDDVTPADEADYSFVP------EGFACNLSA 627
W K+G+++ P D + +++LTI+ VT D+A+Y+ V + L+
Sbjct: 25418 WYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV 25477
Query: 628 KLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQK 685
LH P + + +C G + ++ +SG P PT+ W+K
Sbjct: 25478 TLHPPPTDSTLRPMFKRLLANAECQ----------EGQSVCFEIRVSGIPPPTLKWEK 25525
Score = 35.4 bits (80), Expect = 0.35
Identities = 16/47 (34%), Positives = 30/47 (63%)
Query: 40 VRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYAVIAGSS 86
V++ R G++I +S + ++ EG ++L + E P D G+Y+V A +S
Sbjct: 135 VKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNS 181
Score = 35.4 bits (80), Expect = 0.35
Identities = 45/203 (22%), Positives = 72/203 (35%), Gaps = 60/203 (29%)
Query: 40 VRWQRGGSDISASN---KYGLATEGTRHTLTVREVGPADQGSYAVIAGSSKVKFDLKVIE 96
V W + G I + KY ++ + LT+ V D Y V+A + + +
Sbjct: 25416 VTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGE------D 25469
Query: 97 AEKAEPMLAPAPAPAEATGAPGEAPAPAAELGESAPSPKGSSSAALNGPTPGAPDDPIGL 156
+ KA+ + P P ++T P +
Sbjct: 25470 SCKAKLTVTLHPPPTDSTLRP--------------------------------------M 25491
Query: 157 FVMRPQDGEVTVGGSITFSARVAGASLLKPPVVKWFK-GKWVDLSSKVGQHLQLHDSYDR 215
F + E G S+ F RV+G + PP +KW K G+ + L + +H+ D
Sbjct: 25492 FKRLLANAECQEGQSVCFEIRVSG---IPPPTLKWEKDGQPLSLGPNIEI---IHEGLD- 25544
Query: 216 ASKVYLFELHITDAQPAFTGSYR 238
+ LHI D P TG YR
Sbjct: 25545 -----YYALHIRDTLPEDTGYYR 25562
Score = 35.0 bits (79), Expect = 0.46
Identities = 19/65 (29%), Positives = 28/65 (43%)
Query: 17 RSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQ 76
+ V VF E G K +W R I S+KY + + +TL +R+ DQ
Sbjct: 6342 KDTRVKEQQEVVFNCEVNTEGAKAKWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLDDQ 6401
Query: 77 GSYAV 81
+Y V
Sbjct: 6402 ANYNV 6406
Score = 34.3 bits (77), Expect = 0.78
Identities = 20/85 (23%), Positives = 36/85 (42%), Gaps = 9/85 (10%)
Query: 5 GKKPVSAFSKKPRSVEVAAG--SPAVFEAETERAGVKVR-------WQRGGSDISASNKY 55
GKK KPR + + G V E + + VKV W + G ++ S++
Sbjct: 2296 GKKTTCKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRV 2355
Query: 56 GLATEGTRHTLTVREVGPADQGSYA 80
+ + H L + ++ D G+Y+
Sbjct: 2356 HIVIDKQSHMLLIEDMTKEDAGNYS 2380
Score = 34.3 bits (77), Expect = 0.78
Identities = 24/87 (27%), Positives = 42/87 (48%), Gaps = 4/87 (4%)
Query: 1179 EAPS-FTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLT 1237
EAP+ F + L +++V A+ C + K + W++NG ++ E +++ F K G +
Sbjct: 6515 EAPTEFVEHLEDQTVTEFDDAVFSCQL-SREKANVKWYRNGREIKEGKKYK-FEKDGSIH 6572
Query: 1238 LEIRKPCPFDGGI-YVCRATNLQGEAR 1263
I K C D Y C + + AR
Sbjct: 6573 RLIIKDCRLDDECEYACGVEDRKSRAR 6599
Score = 34.3 bits (77), Expect = 0.78
Identities = 20/65 (30%), Positives = 33/65 (50%), Gaps = 5/65 (7%)
Query: 393 EVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCV----VGGEKCSTELF 448
++KW + G+E+ S KY S G TLT+ D+ Y C+ VG + S++L
Sbjct: 24258 DIKWYRFGKELIQS-RKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLL 24316
Query: 449 VKEPP 453
++ P
Sbjct: 24317 LQATP 24321
Score = 33.9 bits (76), Expect = 1.0
Identities = 24/92 (26%), Positives = 34/92 (36%)
Query: 1179 EAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTL 1238
EAP L + +V G TA C ++ ++W G + E R + + L
Sbjct: 3487 EAPKIFLHLQDVTVKCGDTAQFLCVLKDDSFIDVTWTHEGAKIEESERLKQSQNGNIQFL 3546
Query: 1239 EIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
I D G+Y C N GE L V
Sbjct: 3547 TICNVQLVDQGLYSCIVHNDCGERTTSAVLSV 3578
Score = 33.9 bits (76), Expect = 1.0
Identities = 17/59 (28%), Positives = 27/59 (45%)
Query: 24 GSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYAVI 82
GS A+FE + W + GS+I S K+ +G L + +V +D G Y +
Sbjct: 4828 GSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYTCV 4886
Score = 33.5 bits (75), Expect = 1.3
Identities = 25/125 (20%), Positives = 50/125 (40%), Gaps = 7/125 (5%)
Query: 16 PRSVEVAAGSPAVFEAETE-RAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPA 74
P + + AG EA + +W++G ++ S+ + + L +++V
Sbjct: 12600 PEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRK 12659
Query: 75 DQGSYAVIAGSSKVKFDLKVIEAEKAEPMLAPAPAPAEATGAPGEAPAPAAELGESAPSP 134
D G Y++ A +S + +K + ++ AP P + + A A L P
Sbjct: 12660 DSGYYSLTAENS------SGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSLSWHIPLE 12713
Query: 135 KGSSS 139
G S+
Sbjct: 12714 DGGSN 12718
Score = 33.1 bits (74), Expect = 1.7
Identities = 53/201 (26%), Positives = 74/201 (36%), Gaps = 44/201 (21%)
Query: 87 KVKFDLKVIEAEKAEPMLAP--APAPAEATGAPGEAPAPAAELGE----------SAPSP 134
K + ++K I+ EP P AP G EA AP E + PSP
Sbjct: 4719 KPEAEVKTIKPPPVEPEPTPIAAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPSP 4778
Query: 135 KGSSSAALNGPTPGA--PDD----------PIGLFVMRPQDGEVT----VGGSITFSARV 178
+ L + G PD+ P+ FV +D +T VG S F V
Sbjct: 4779 IEAERRKLRPGSGGEKPPDEAPFTYQLKAVPLK-FVKEIKDIILTESEFVGSSAIFECLV 4837
Query: 179 AGASLLKPPVVKWFK-GKWVDLSSKVGQHLQLHDSYDRASKVYLFELHITDAQPAFTGSY 237
+ ++ + W K G + S K H + D DR +LHI D Q + G Y
Sbjct: 4838 SPSTA----ITTWMKDGSNIRESPK---HRFIADGKDR-------KLHIIDVQLSDAGEY 4883
Query: 238 RCEVSTKDKFDCSNFNLTVHE 258
C + +K S L V E
Sbjct: 4884 TCVLRLGNKEKTSTAKLVVEE 4904
Score = 33.1 bits (74), Expect = 1.7
Identities = 16/72 (22%), Positives = 31/72 (43%)
Query: 27 AVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYAVIAGSS 86
AVF E ++V+W + + + + EG H++T +++ D V A
Sbjct: 5641 AVFTVELSHDNIRVKWFKNDQRLHTTRSVSMQDEGKTHSITFKDLSIDDTSQIRVEAMGM 5700
Query: 87 KVKFDLKVIEAE 98
+ L V+E +
Sbjct: 5701 SSEAKLTVLEGD 5712
Score = 33.1 bits (74), Expect = 1.7
Identities = 21/84 (25%), Positives = 38/84 (45%), Gaps = 5/84 (5%)
Query: 19 VEVAAGSPAVFEAETE-RAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQG 77
V + AGS V +A + K+ W +G ++ K L G R T ++ +D G
Sbjct: 22752 VTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSG 22811
Query: 78 SYAV----IAGSSKVKFDLKVIEA 97
Y + +G+ V +KV+++
Sbjct: 22812 KYTLTVKNASGTKAVSVMVKVLDS 22835
Score = 32.7 bits (73), Expect = 2.3
Identities = 21/72 (29%), Positives = 35/72 (48%), Gaps = 2/72 (2%)
Query: 460 LEDQLVMVGQRVEFECEVSEEGA-QVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAM 518
+++ ++ G V F C++S ++ W KDG + E ++ F +DG R L I +
Sbjct: 1251 IKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDG-RASLRIPVVL 1309
Query: 519 LEDAGHYALCTS 530
ED G Y S
Sbjct: 1310 PEDEGIYTAFAS 1321
Score = 32.3 bits (72), Expect = 3.0
Identities = 43/171 (25%), Positives = 67/171 (39%), Gaps = 22/171 (12%)
Query: 948 NMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQT--IQKKVGEPVNLLIPFQGKPRPQV 1005
N G G T TE + + + P L++ I+ G P G+P P V
Sbjct: 3739 NSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTV 3798
Query: 1006 TWTKEGQPL-AGEEVSIRNSPTDTILFI-RAARRVHSGTYQVTVRIENMEDKAT------ 1057
TW KE + L +I ++P + FI +R SG Y + ENM ++T
Sbjct: 3799 TWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLY--ICKAENMLGESTCAAELL 3856
Query: 1058 LVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKK 1108
++L+ D P + T + P+D T L G V+ D +
Sbjct: 3857 VLLEDTDMTDTPCKAKSTP----------EAPEDFPQTPLKGPAVEALDSE 3897
Score = 32.3 bits (72), Expect = 3.0
Identities = 22/83 (26%), Positives = 34/83 (40%), Gaps = 1/83 (1%)
Query: 12 FSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREV 71
F+ + V V A FE R V W +G I +S+K+ + +G +H L + +
Sbjct: 5183 FAVPLKDVTVPERRQARFECVLTREA-NVIWSKGPDIIKSSDKFDIIADGKKHILVINDS 5241
Query: 72 GPADQGSYAVIAGSSKVKFDLKV 94
D+G Y K L V
Sbjct: 5242 QFDDEGVYTAEVEGKKTSARLFV 5264
Score = 32.3 bits (72), Expect = 3.0
Identities = 24/67 (35%), Positives = 30/67 (44%), Gaps = 5/67 (7%)
Query: 467 VGQRVEFECEVSEEG---AQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAG 523
V R + + +V +G A V W KDG L +ET + L I EA ED G
Sbjct: 19101 VKAREQLKIDVPFKGRPQATVNWRKDGQTL--KETTRVNVSSSKTVTSLSIKEASKEDVG 19158
Query: 524 HYALCTS 530
Y LC S
Sbjct: 19159 TYELCVS 19165
Score = 32.0 bits (71), Expect = 3.9
Identities = 21/81 (25%), Positives = 35/81 (43%), Gaps = 1/81 (1%)
Query: 6 KKPVSAFSKKPRSVEVAAGSPAVFEAETERA-GVKVRWQRGGSDISASNKYGLATEGTRH 64
K+ +K +EVA G A F E + A V+ +W + G +I S+K + +
Sbjct: 4525 KRAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYIS 4584
Query: 65 TLTVREVGPADQGSYAVIAGS 85
+L + D G Y A +
Sbjct: 4585 SLEILRTQVVDCGEYTCKASN 4605
Score = 32.0 bits (71), Expect = 3.9
Identities = 22/76 (28%), Positives = 33/76 (43%), Gaps = 1/76 (1%)
Query: 1179 EAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTL 1238
E FT+ L N V T L C V P ++ W+K ++ E R+ + ++ L
Sbjct: 6156 EEAVFTKNLANIEVSETDTIKLVCEV-SKPGAEVIWYKGDEEIIETGRYEILTEGRKRIL 6214
Query: 1239 EIRKPCPFDGGIYVCR 1254
I+ D G Y CR
Sbjct: 6215 VIQNAHLEDAGNYNCR 6230
Score = 32.0 bits (71), Expect = 3.9
Identities = 22/61 (36%), Positives = 30/61 (49%), Gaps = 2/61 (3%)
Query: 988 GEPVNLLIPFQGKPRPQVTWTKEGQPLA-GEEVSIRNSPTD-TILFIRAARRVHSGTYQV 1045
G+ V I G P P + W K+GQPL+ G + I + D L IR +G Y+V
Sbjct: 25504 GQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRV 25563
Query: 1046 T 1046
T
Sbjct: 25564 T 25564
Score = 31.6 bits (70), Expect = 5.1
Identities = 23/81 (28%), Positives = 33/81 (40%), Gaps = 5/81 (6%)
Query: 21 VAAGSPAVFEAETERAGVKV-RWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSY 79
V AG+ F A V +W GS+I Y + T+ LT++ D G Y
Sbjct: 11217 VKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEY 11276
Query: 80 AV----IAGSSKVKFDLKVIE 96
+ AGS V L V++
Sbjct: 11277 QITVSNAAGSKTVAVHLTVLD 11297
Score = 31.6 bits (70), Expect = 5.1
Identities = 25/107 (23%), Positives = 43/107 (40%), Gaps = 11/107 (10%)
Query: 18 SVEVAAGSPAVFEAETERAGVK-VRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQ 76
++ V AG EA+ + + W RG +I S + + + L V++ D
Sbjct: 17329 TIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDG 17388
Query: 77 GSYAV----IAGSSKVKFDLKVIEAEKAEPMLAPAPAPAEATGAPGE 119
G Y + +AGS ++KV++ P P + TG E
Sbjct: 17389 GQYILRASNVAGSKSFPVNVKVLDRP------GPPEGPVQVTGVTSE 17429
Score = 31.6 bits (70), Expect = 5.1
Identities = 32/96 (33%), Positives = 42/96 (43%), Gaps = 18/96 (18%)
Query: 988 GEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDT----ILFIRAARRVHSGTY 1043
GE G+P P VTW ++GQ L+ S R+ T T I + + G Y
Sbjct: 26270 GESARFSCDTDGEPVPTVTWLRKGQVLS---TSARHQVTTTKYKSTFEISSVQASDEGNY 26326
Query: 1044 QVTVRIENMEDKA----TLVLQ---VVDK--PSPPQ 1070
V V EN E K TL +Q V +K SPP+
Sbjct: 26327 SVVV--ENSEGKQEAEFTLTIQKARVTEKAVTSPPR 26360
Score = 31.2 bits (69), Expect = 6.6
Identities = 20/71 (28%), Positives = 31/71 (43%), Gaps = 1/71 (1%)
Query: 1183 FTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRK 1242
F +PL + V A C + K+ WFK+G ++ + ++ + SK V L I K
Sbjct: 6071 FLRPLTDLQVREKEMARFECEL-SRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINK 6129
Query: 1243 PCPFDGGIYVC 1253
D Y C
Sbjct: 6130 CLLDDEAEYSC 6140
Score = 31.2 bits (69), Expect = 6.6
Identities = 43/175 (24%), Positives = 71/175 (40%), Gaps = 15/175 (8%)
Query: 379 HKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRT-LTISQCSLADDAAYQCV 437
+ + L+ E +HD + L E+Q GS K T TI+ ++ +++
Sbjct: 15758 NSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATCATVKVTEATITGLIQGEEYSFRVS 15817
Query: 438 VGGEKCSTELFVKEPPV----LITRPLEDQL-----VMVGQRVEFECE-VSEEGAQVKWL 487
EK ++ PV L+ P L V+ G+ ++ + + V W
Sbjct: 15818 AQNEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWH 15877
Query: 488 KDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYA--LCTSGGQALAELIV 540
KD V L ++T + + L I +A ED GHY L S G+A+ L V
Sbjct: 15878 KDNVPL--KQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNV 15930
Score = 31.2 bits (69), Expect = 6.6
Identities = 23/87 (26%), Positives = 39/87 (44%), Gaps = 3/87 (3%)
Query: 23 AGSPAVFEAETE-RAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSY-A 80
AGSP + R KV W+ + +++ + T R TLTV++ D G Y
Sbjct: 22356 AGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFL 22415
Query: 81 VIAGSSKVK-FDLKVIEAEKAEPMLAP 106
+ ++ VK F + V+ + P+ P
Sbjct: 22416 TLENTAGVKTFSVTVVVIGRPGPVTGP 22442
Score = 31.2 bits (69), Expect = 6.6
Identities = 31/113 (27%), Positives = 44/113 (38%), Gaps = 8/113 (7%)
Query: 963 TVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPL-AGEEVSI 1021
T++ + + P LP + + VGE V + P P VTW K GQ + G+
Sbjct: 25377 TMRLLERPPEFTLPLYNKTAY---VGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKK 25433
Query: 1022 RNSPTDTILF---IRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQD 1071
+D L+ I + Y V R + ED L V P PP D
Sbjct: 25434 YTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHP-PPTD 25485
Score = 30.8 bits (68), Expect = 8.6
Identities = 22/97 (22%), Positives = 44/97 (45%), Gaps = 3/97 (3%)
Query: 981 QTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLA-GEEVSIRNSPTDTILFIRAARRVH 1039
Q + + G+P G+P+P+++W KE Q L+ G + + + L + A
Sbjct: 3200 QPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPED 3259
Query: 1040 SGTYQVTVRIEN--MEDKATLVLQVVDKPSPPQDLRV 1074
+ Y + + A+L ++V + SP Q++ V
Sbjct: 3260 AAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPV 3296
Score = 30.8 bits (68), Expect = 8.6
Identities = 20/78 (25%), Positives = 31/78 (39%)
Query: 21 VAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYA 80
V G A F E + V W + + + S +++EG H L ++EV D
Sbjct: 5280 VKEGETATFVCELSHEKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQIK 5339
Query: 81 VIAGSSKVKFDLKVIEAE 98
LKV+EA+
Sbjct: 5340 AQVKELSSTAQLKVLEAD 5357
>gi|110349713 titin isoform novex-1 [Homo sapiens]
Length = 27051
Score = 286 bits (732), Expect = 9e-77
Identities = 238/845 (28%), Positives = 366/845 (43%), Gaps = 77/845 (9%)
Query: 386 ELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCST 445
+L+ A VKW +NG+EI+ G KY FE G+ L I C L D+ Y C V K
Sbjct: 6473 QLSREKANVKWYRNGREIK-EGKKYKFEKDGSIHRLIIKDCRLDDECEYACGVEDRKSRA 6531
Query: 446 ELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKK 505
LFV+E PV I RP +D L G V F E++++ +V+WL++ + + + + K++
Sbjct: 6532 RLFVEEIPVEIIRPPQDILEAPGADVVFLAELNKDKVEVQWLRNNMVVVQGD--KHQMMS 6589
Query: 506 DGQRHHLIINEAMLEDAGHYALCTSGGQALAEL-IVQEKKLEVYQSIADLMVGAKDQAVF 564
+G+ H L I + D G Y +A A+L + K++ + VG V
Sbjct: 6590 EGKIHRLQICDIKPRDQGEYRFIAKDKEARAKLELAAAPKIKTADQDLVVDVGKPLTMVV 6649
Query: 565 KCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACN 624
+ + W K + L S + I + D+ Y V + N
Sbjct: 6650 PYDAYPK-AEAEWFKENEPL---STKTIDTTAEQTSFRILEAKKGDKGRYKIVLQ----N 6701
Query: 625 LSAKLH-FMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIW 683
K F+ +K+ +D PG + + L+V + D ++ W
Sbjct: 6702 KHGKAEGFINLKV------------IDVPGPVRN-----------LEVTETFDGEVSLAW 6738
Query: 684 QKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEK 743
++ +T G + + + D+ CE FTV G +K
Sbjct: 6739 EEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAESCE---------------FTVTGLQK 6783
Query: 744 ED-EGVYTVTVKNPVGEDQVNLTVKVI------DVPDAPAAPKISNVGEDSCTVQWEPPA 796
E ++ V+ +N VG + T + DVP P I++V ++ WEPP
Sbjct: 6784 GGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRFGVSLTWEPPE 6843
Query: 797 YDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSR 856
YDGG I Y++E + K S RW ++LS ++EG Y RV A N IG+ +
Sbjct: 6844 YDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGK 6903
Query: 857 PSPASQPFM----PIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEG 912
PS A+ PF+ PI PS P +L D + ++V LKW PP + G + GY +E C EG
Sbjct: 6904 PSAAT-PFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEG 6962
Query: 913 CSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPR 972
W+ L + V L G + L+RV A N AG P P+T + P
Sbjct: 6963 KDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPT 7022
Query: 973 LQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPL-AGEEVSIRNSPTDTILF 1031
+ L + ++ V P+ +L+P G PRP TW + L G+ V ++ L
Sbjct: 7023 MDLSA-FKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELV 7081
Query: 1032 IRAARRVHSGTYQVTVRIENMED--KATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPP 1089
I + R G Y T+++EN + + V+ +PS P++L+ D +V L W+PP
Sbjct: 7082 ISPSERSDKGIY--TLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHLTWEPP 7139
Query: 1090 QDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSD 1149
D G + L GY V+K + W V++ VP+L+ G Y F+V ++N G
Sbjct: 7140 DDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCG-PG 7198
Query: 1150 RAATTKEPVFIPRPGITYEPP-NYKALDFSEAPSFT--QPLVN--RSVIAGYTAMLCCAV 1204
A EPV + P +PP N K D + F P N S I GY C
Sbjct: 7199 EPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERC--P 7256
Query: 1205 RGSPK 1209
RGS K
Sbjct: 7257 RGSDK 7261
Score = 243 bits (619), Expect = 1e-63
Identities = 204/708 (28%), Positives = 303/708 (42%), Gaps = 81/708 (11%)
Query: 567 EVSDENVRGVWLKNGKELVPDSRIKVSHI--GRVHKLTIDDVTPADEADYSFVPEGFACN 624
+V DE R + E P+++ KV+ + G+ +K + V A E+D + VPE
Sbjct: 10781 KVGDEEWRRA--NHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVK 10838
Query: 625 LSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQ 684
R EPP++ LD I V G+ LRL I G P P V W+
Sbjct: 10839 ---------------DRLEPPELILDANMAREQHIKV--GDTLRLSAIIKGVPFPKVTWK 10881
Query: 685 KAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKE 744
K DAP + R++ T S + A E
Sbjct: 10882 KEDR-----------DAPT--------------------KARIDVTPVGSKLEIRNAAHE 10910
Query: 745 DEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPIL 804
D G+Y++TV+NP G V++ V V+D P P ++S + +DSC + W+ P DGG I
Sbjct: 10911 DGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVIT 10970
Query: 805 GYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMS------RPS 858
Y++ER+ S +W L+ ++ SH A+ + EG Y RV A N G +P
Sbjct: 10971 NYVVERRDVASAQWSPLS-ATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPI 11029
Query: 859 PASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVA 918
A P P GPP + H+ DV T VSL W P+R G + GY VEY EG +W+
Sbjct: 11030 KALDPLHPPGPPKDLHHV---DVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIK 11086
Query: 919 ALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRH 978
+ +V L G FRV+A N+ G G P TT P+ QE L P ++L
Sbjct: 11087 F--KTVTNLECVVTGLQQGKTYRFRVKAENIVGLGLP-DTTIPIECQEKLVPPSVELDVK 11143
Query: 979 LRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPL-AGEEVSIRNSPTDTILFIRAARR 1037
L + + K G V +G P P WT +G + E ++ ++L I+ R
Sbjct: 11144 LIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLR 11203
Query: 1038 VHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQ-DLRVTDAWGLNVALEWKPPQDVGNTE 1096
+G YQ+TV + L V+D P PP + + D ++ + W+PP+D G +
Sbjct: 11204 RDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTISWQPPKDDGGSP 11263
Query: 1097 LWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFS---DRAAT 1153
+ Y V+K D + W V +T +P L G Y FRV ++N +G D T
Sbjct: 11264 VINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPT 11323
Query: 1154 TKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVN-RSVIAGY------TAMLCCAVRG 1206
+ F P P +P + + S+T P + S I GY V
Sbjct: 11324 VAKHKFSP-PSPPGKPVVTDITENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVNK 11382
Query: 1207 SPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCR 1254
+P + + GL G FR+F++ + KP P I CR
Sbjct: 11383 TPIADLKFRVTGLYEGNTYEFRVFAEN---LAGLSKPSPSSDPIKACR 11427
Score = 238 bits (608), Expect = 2e-62
Identities = 190/681 (27%), Positives = 288/681 (42%), Gaps = 96/681 (14%)
Query: 344 DLRGMLKRLKGMRRDEKKSTAFQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEI 403
DLR +++ LK + EKKS F K+ RL V L KW KNG+E+
Sbjct: 6361 DLR-IVEPLKDIETMEKKSVTFWCKVN-----------RLNVTL-------KWTKNGEEV 6401
Query: 404 QMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCSTELFVKEPPVLITRPLEDQ 463
++ + K LTI C D+ Y G +K EL + E P LEDQ
Sbjct: 6402 PFD-NRVSYRVDKYKHMLTIKDCGFPDEGEYIVTAGQDKSVAELLIIEAPTEFVEHLEDQ 6460
Query: 464 LVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAG 523
V F C++S E A VKW ++G E+ +E KY+F+KDG H LII + L+D
Sbjct: 6461 TVTEFDDAVFSCQLSREKANVKWYRNGREI--KEGKKYKFEKDGSIHRLIIKDCRLDDEC 6518
Query: 524 HYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKE 583
YA ++ A L V+E +E+ + D++ VF E++ + V WL+N
Sbjct: 6519 EYACGVEDRKSRARLFVEEIPVEIIRPPQDILEAPGADVVFLAELNKDKVEVQWLRNNMV 6578
Query: 584 LVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQE 643
+V + ++ G++H+L I D+ P D+ +Y F+ AK K++
Sbjct: 6579 VVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFI---------AKDKEARAKLELA---A 6626
Query: 644 PPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPE 703
PKI +VV G L + VP P W K
Sbjct: 6627 APKIK-----TADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKE----------------- 6664
Query: 704 DTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVN 763
++ L +T ++TT +++ F + A+K D+G Y + ++N G+ +
Sbjct: 6665 ----------NEPLSTKT-----IDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGF 6709
Query: 764 LTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNF 823
+ +KVIDVP +++ + ++ WE P DGG I+GY++ER+ K W+ L
Sbjct: 6710 INLKVIDVPGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWV-LAT 6768
Query: 824 DLIQELSHEARRMIE-GVVYEMRVYAVNAIGMSRPSPASQPF---MPIGPPSEPTHLAVE 879
D + + + GV Y RV A N +G P P P P ++ +
Sbjct: 6769 DRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTIT 6828
Query: 880 DVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGAR 939
DV+ VSL W PPE G + Y +E + W A+ E S V D+ G
Sbjct: 6829 DVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQE 6888
Query: 940 LLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQG 999
FRVRA N G G P T V V + ++RP PVNL Q
Sbjct: 6889 YSFRVRAQNRIGVGKPSAATPFVKVADPIERP----------------SPPVNLTSSDQT 6932
Query: 1000 KPRPQVTWTKE----GQPLAG 1016
+ Q+ W G P+ G
Sbjct: 6933 QSSVQLKWEPPLKDGGSPILG 6953
Score = 236 bits (601), Expect = 1e-61
Identities = 159/530 (30%), Positives = 248/530 (46%), Gaps = 48/530 (9%)
Query: 641 RQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPD 700
R EPP+I LD R +V+ A LRL V I G P P V W+KA
Sbjct: 18729 RIEPPEIELDADLR--KVVVLRASATLRLFVTIKGRPEPEVKWEKA-------------- 18772
Query: 701 APEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGED 760
+ +L + R ++E T ++ ++ + D G Y +T++N G
Sbjct: 18773 --------------EGILTD---RAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSGSK 18815
Query: 761 QVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKK--KKSYRW 818
+ V+V+D P AP I V +DS T+ WEPP DGG I YI+E+++ +K+Y
Sbjct: 18816 TAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYAT 18875
Query: 819 MRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAV 878
+ N + + + EG Y RV A N G+ P+ ++P PP P + +
Sbjct: 18876 ITNN---CTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTL 18932
Query: 879 EDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGA 938
DV+ T ++KW PE G + GY VE +G +W Q T +I L G
Sbjct: 18933 VDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVKTLEATI--SGLTAGE 18990
Query: 939 RLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQ 998
+FRV A N G P PV ++I +P ++LP H T K E + + +PF+
Sbjct: 18991 EYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFH---TFNVKAREQLKIDVPFK 19047
Query: 999 GKPRPQVTWTKEGQPLAGE-EVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKAT 1057
G+P+ V W K+GQ L V++ +S T T L I+ A + GTY++ V
Sbjct: 19048 GRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVP 19107
Query: 1058 LVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLE 1117
+ + V+D+P PP +R+ + ++ + W PP+ G ++ Y V+K + + W V +
Sbjct: 19108 ITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQ 19167
Query: 1118 HYRRTHCVVPELIIGNGYYFRVFSQNMVG---FSDRAATTKEPVFIPRPG 1164
RT + L G+ Y FRV ++N G +S+ +A E F P PG
Sbjct: 19168 AVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSP-PG 19216
Score = 234 bits (596), Expect = 5e-61
Identities = 179/608 (29%), Positives = 272/608 (44%), Gaps = 59/608 (9%)
Query: 577 WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKI 636
W G +L R+ V +V KLTI + T D +Y+ + S +K+
Sbjct: 23400 WFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSET-----IKV 23454
Query: 637 DFVPRQEPPK--IHLDCPGRIPDTIVVVAGNKLRLD--VPISGDPAPTVIWQKAITQGNK 692
+ + PP I +D I T + ++ LD P+SG V+ Q+
Sbjct: 23455 IILDKPGPPTGPIKID---EIDATSITISWEPPELDGGAPLSG----YVVEQR------- 23500
Query: 693 APARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVT 752
DA G + V + RS F + +E V+ V
Sbjct: 23501 -------DA------------------HRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVA 23535
Query: 753 VKNPVG-----EDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYI 807
N G + +V I +P P +I +V D T+ W PP DGG + GYI
Sbjct: 23536 ATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYI 23595
Query: 808 LERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM-- 865
+ERK+ ++ RW+R+N + + + + EG+ YE RV A+NA G +PS S+P +
Sbjct: 23596 VERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAM 23655
Query: 866 -PIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLT 924
PI PP +P + V D + T+VSL W PE G + GY +E EW T
Sbjct: 23656 DPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPT 23715
Query: 925 EHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQ 984
+ + LP GA FRV A N GPG P V V E+L+ P +L ++ I
Sbjct: 23716 KIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGIF 23775
Query: 985 KKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQ 1044
+ G + L IP +GKP P WTKEGQ ++ + I S T T L I+ A R SGTY
Sbjct: 23776 VRQGGVIRLTIPIKGKPFPICKWTKEGQDIS-KRAMIATSETHTELVIKEADRGDSGTYD 23834
Query: 1045 VTVRIENMEDKATLVLQVVDKPSPPQ-DLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQ 1103
+ + + + + ++V+ P+ P+ L D +V + W+PP D G ++ GY ++
Sbjct: 23835 LVLENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILE 23894
Query: 1104 KADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRP 1163
+ + W+T+ R T VV L Y+FRV ++N G S + ++EPV P
Sbjct: 23895 RREVPKAAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAENQFGIS-KPLKSEEPVTPKTP 23953
Query: 1164 GITYEPPN 1171
EPP+
Sbjct: 23954 LNPPEPPS 23961
Score = 232 bits (591), Expect = 2e-60
Identities = 155/508 (30%), Positives = 236/508 (46%), Gaps = 43/508 (8%)
Query: 702 PEDTGDSD--EWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVG- 758
P+D G S +V +K+ + V V + +T+ + E V+ + +N G
Sbjct: 9869 PKDDGGSKITNYVIEKRE-ANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGI 9927
Query: 759 ----EDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKK 814
+ + + VP AP P +S+V +S TV WE P YDGG P+ GY LE K
Sbjct: 9928 GEPLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTT 9987
Query: 815 SYRWMRLNFDLIQEL----SHEARRMIEGVVYEMRVYAVNAIGM------SRPSPASQPF 864
S RW R+N D I+ + S++ +IEG Y+ RVYA+NA G+ S P+ A P
Sbjct: 9988 SKRWKRVNRDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPI 10047
Query: 865 MPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLT 924
P GPP V D + ++ L+W PP + G + GY VEY EG EW
Sbjct: 10048 APPGPPFPK----VTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEV 10103
Query: 925 EHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQ 984
T ++V L GA FRVRA N+AG G P T+ + +++ L P LQL +R I
Sbjct: 10104 RGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRDRIV 10163
Query: 985 KKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQ 1044
G + ++ GKP P VTW + L +E +I + + + I+ +R H G Y
Sbjct: 10164 VHAGGVIRIIAYVSGKPPPTVTWNMNERTLP-QEATIETTAISSSMVIKNCQRSHQGVYS 10222
Query: 1045 VTVRIENMEDKATLVLQVVDKPSP-PQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQ 1103
+ + E E K T+++ V+D P P + + L W P+D G + + Y ++
Sbjct: 10223 LLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIE 10282
Query: 1104 KADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGF-----SDRAATTKEPV 1158
K + W V R + V LI G Y+FR+ ++N +G + A +EP+
Sbjct: 10283 KRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPI 10342
Query: 1159 FIP-RP-------------GITYEPPNY 1172
+P RP +T+ PP Y
Sbjct: 10343 TVPERPEDLEVKEVTKNTVTLTWNPPKY 10370
Score = 232 bits (591), Expect = 2e-60
Identities = 161/590 (27%), Positives = 263/590 (44%), Gaps = 48/590 (8%)
Query: 643 EPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAP 702
E P++ LD + IVV AG R+ +P G P P + W +
Sbjct: 17648 EAPELDLD--SELRKGIVVRAGGSARIHIPFKGRPTPEITWSR----------------- 17688
Query: 703 EDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQV 762
+E F K V++E + + +++ ++ D G Y + ++N G
Sbjct: 17689 ------EEGEFTDK--------VQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSA 17734
Query: 763 NLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLN 822
+TVKV+D P P + V +DS + WEPP DGG + Y++++++ + ++
Sbjct: 17735 FVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRESTRKAYANVS 17794
Query: 823 FDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVS 882
+ S + + EG +Y RV A N G+ P PPS P + + DVS
Sbjct: 17795 -SKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEPPSPPGKVTLTDVS 17853
Query: 883 DTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLF 942
T+ SL W PE G + GY VE P+G +W ++ ++ + +V L +G F
Sbjct: 17854 QTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKW--SIVAESKVCNAVVTGLSSGQEYQF 17911
Query: 943 RVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPR 1002
RV+A+N G P PV +++ +P L+LP + T + GE + + IP G+PR
Sbjct: 17912 RVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFN---TYSIQAGEDLKIEIPVIGRPR 17968
Query: 1003 PQVTWTKEGQPL-AGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQ 1061
P ++W K+G+PL V++ + T T+L I+ + G Y VT L +
Sbjct: 17969 PNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVI 18028
Query: 1062 VVDKPSPP-QDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYR 1120
V++KP PP +R + V + W+PP G ++ Y V+K D T W V
Sbjct: 18029 VLEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATVA 18088
Query: 1121 RTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEA 1180
RT + +L G Y FR+F++N G S A + V + P ++ P F +
Sbjct: 18089 RTTIKITKLKTGTEYQFRIFAENRYGKS--APLDSKAVIVQYP---FKEPGPPGTPFVTS 18143
Query: 1181 PSFTQPLV--NRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFR 1228
S Q LV + V G T ++ + K I W K +D +F+
Sbjct: 18144 ISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFK 18193
Score = 231 bits (588), Expect = 4e-60
Identities = 175/602 (29%), Positives = 274/602 (45%), Gaps = 99/602 (16%)
Query: 643 EPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIW------------------- 683
EPP++ +D R D IVV AG L+++ I+G P P + W
Sbjct: 19413 EPPRVMMDVKFR--DVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTD 19470
Query: 684 ----------------QKAITQGNKAPAR-----------PAPDA--------------- 701
Q +T N A R P P A
Sbjct: 19471 NHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSL 19530
Query: 702 ----PEDTG--DSDEWVFDKK-------LLCETEGRVRVETTKDRSIFTVEGAEKEDEGV 748
P++ G D D ++ +K+ +CE G +++ + K + K +E +
Sbjct: 19531 SWGRPQEDGGADIDYYIVEKRETSHLAWTICE--GELQMTSCKVTKLL------KGNEYI 19582
Query: 749 YTVTVKNP--VGEDQVNLTVKVID---VPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPI 803
+ VT N VGE ++ +K +D VP P + +I++V ++S T+ W P DGG I
Sbjct: 19583 FRVTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEI 19642
Query: 804 LGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRP---SPA 860
GYI+ER++K S RW+R+N + +L ++ + EG YE RVYA NA G+S P SP
Sbjct: 19643 SGYIIERREKNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPL 19702
Query: 861 SQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAAL 920
+ P+ PS P+ + D TT+++ W P G + GY+VEY ++W ++
Sbjct: 19703 IRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSI 19762
Query: 921 QGL--TEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRH 978
Q L TE+T + L TGA +FRV++ N G P +++P +E + P +
Sbjct: 19763 QSLRGTEYT---ISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSE 19819
Query: 979 LRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRV 1038
+R+T+ K G + +PF+G+P P V W+K L + + + T L I A R
Sbjct: 19820 MRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLR-TRAYVDTTDSRTSLTIENANRN 19878
Query: 1039 HSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELW 1098
SG Y +T++ TLV++V+D P PP ++ V D + L W P++ G +
Sbjct: 19879 DSGKYTLTIQNVLSAASLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDVPENDGGAPVK 19938
Query: 1099 GYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPV 1158
Y ++K + W +V + R V L G YYFRV +N G A TKE V
Sbjct: 19939 NYHIEKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVG-IPAETKEGV 19997
Query: 1159 FI 1160
I
Sbjct: 19998 KI 19999
Score = 230 bits (587), Expect = 6e-60
Identities = 151/532 (28%), Positives = 240/532 (45%), Gaps = 42/532 (7%)
Query: 641 RQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPD 700
R+E P +D R T++V AG + VP G P P V+W K PD
Sbjct: 19808 REEEPLFDIDSEMR--KTLIVKAGASFTMTVPFRGRPVPNVLWSK-------------PD 19852
Query: 701 APEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGED 760
T R V+TT R+ T+E A + D G YT+T++N +
Sbjct: 19853 TDLRT------------------RAYVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAA 19894
Query: 761 QVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMR 820
+ L VKV+D P P + +V ++S + W+ P DGG P+ Y +E+++ W+
Sbjct: 19895 SLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDVPENDGGAPVKNYHIEKREASKKAWVS 19954
Query: 821 LNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVED 880
+ + LS++ + EG +Y RV N G+ P+ + PS P L V
Sbjct: 19955 VTNNC-NRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGVKITEKPSPPEKLGVTS 20013
Query: 881 VSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARL 940
+S +VSL W PE G + Y VE +G WV + + T +V L +
Sbjct: 20014 ISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQKNWVKC--AVAKSTHHVVSGLRENSEY 20071
Query: 941 LFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGK 1000
FRV A N AG P PV ++E L+ P + + T+ + G + + IP GK
Sbjct: 20072 FFRVFAENQAGLSDPRELLLPVLIKEQLEPPEIDMKNFPSHTVYVRAGSNLKVDIPISGK 20131
Query: 1001 PRPQVTWTKEGQPL-AGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLV 1059
P P+VT +++G PL A + + + + ++ + +G Y++T + KA +
Sbjct: 20132 PLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFIN 20191
Query: 1060 LQVVDKPSPPQ-DLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEH 1118
+ V+D+P PP + ++D +V L+W+PP+ G +++ Y + K + T W V
Sbjct: 20192 IVVLDRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSAT 20251
Query: 1119 YRRTHCVVPELIIGNGYYFRVFSQNMVGFSDR----AATTKEPVFIPRPGIT 1166
RT V +L G Y FR+ ++N G SD T K P P P T
Sbjct: 20252 VARTMMKVMKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPST 20303
Score = 229 bits (585), Expect = 1e-59
Identities = 167/615 (27%), Positives = 275/615 (44%), Gaps = 63/615 (10%)
Query: 565 KCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACN 624
+CE +N W++ +LVP+ KV+ + + +K + V+ ++A S P
Sbjct: 6958 RCEEGKDN----WIRCNMKLVPELTYKVTGLEKGNKY-LYRVSAENKAGVSD-PSEILGP 7011
Query: 625 LSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQ 684
L+A F+E +D D + V+ N + + VP +G P PT W
Sbjct: 7012 LTADDAFVEPTMDL--------------SAFKDGLEVIVPNPITILVPSTGYPRPTATW- 7056
Query: 685 KAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKE 744
F K+L ET RV+++T + + +E+
Sbjct: 7057 ---------------------------CFGDKVL-ETGDRVKMKTLSAYAELVISPSERS 7088
Query: 745 DEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPIL 804
D+G+YT+ ++N V + V VI P AP K ++ +DS + WEPP DGG P+
Sbjct: 7089 DKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLT 7148
Query: 805 GYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPF 864
GY++E+++ W ++ D + +L +++G Y +V A N G P+ +P
Sbjct: 7149 GYVVEKREVSRKTWTKV-MDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPV 7207
Query: 865 ---MPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQ 921
P P P ++ D + ++ L W PP+ G + GY VE CP G +WVA +
Sbjct: 7208 NMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGE 7267
Query: 922 GLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQ 981
+ E T + V L G +RV+A N G P TE + + + P + L L
Sbjct: 7268 PVAE-TKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLA 7326
Query: 982 TIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEE-VSIRNSPTDTILFIRAARRVHS 1040
+ K G + L GKP P++TWTK L ++ ++I N P + + I ++R +
Sbjct: 7327 GLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDT 7386
Query: 1041 GTYQVTVRIENMEDKATLVLQ--VVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELW 1098
GTY + N+ +AT V++ V+DKP PP +TD + L W PP+D G +++
Sbjct: 7387 GTY--IIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKIT 7444
Query: 1099 GYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSD----RAATT 1154
Y V++ + W + + T+ +LI Y FRV ++NM G + T
Sbjct: 7445 NYVVERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITA 7504
Query: 1155 KEPVFIPRPGITYEP 1169
K P P EP
Sbjct: 7505 KYQFDPPGPPTRLEP 7519
Score = 225 bits (574), Expect = 2e-58
Identities = 166/609 (27%), Positives = 271/609 (44%), Gaps = 60/609 (9%)
Query: 643 EPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAP 702
E P I LD R I + AG LRL VPI G P P V W K
Sbjct: 16566 EAPDIDLDLELR--KIINIRAGGSLRLFVPIKGRPTPEVKWGKV---------------- 16607
Query: 703 EDTGDSDEWVFDKKLLCETEGRVR----VETTKDRSIFTVEGAEKEDEGVYTVTVKNPVG 758
+G +R ++ T + ++ + D G YT+T++N G
Sbjct: 16608 -------------------DGEIRDAAIIDVTSSFTSLVLDNVNRYDSGKYTLTLENSSG 16648
Query: 759 EDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKK--KKSY 816
+TV+V+D P P K++ + +DS ++ WEPP DGG I YI+E+++ +KSY
Sbjct: 16649 TKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEKREATRKSY 16708
Query: 817 RWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHL 876
+ N + S + ++ EG Y RV A N G+ P+ + P P P +
Sbjct: 16709 AAVVTN---CHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPPGKI 16765
Query: 877 AVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPT 936
V+DV+ +VSL W PE G + Y VE + +W + + ++ +L
Sbjct: 16766 TVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECAR--VKSLQAVITNLTQ 16823
Query: 937 GARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIP 996
G LFRV A N G P + P+ ++++ P ++ P ++Q VG+ + + +P
Sbjct: 16824 GEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVK-PAFSSYSVQ--VGQDLKIEVP 16880
Query: 997 FQGKPRPQVTWTKEGQPL-AGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDK 1055
G+P+P +TWTK+G PL +++ +S T L I+ + G Y +TV +
Sbjct: 16881 ISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKT 16940
Query: 1056 ATLVLQVVDKPSPPQ-DLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFT 1114
A++ + +DKP PP+ ++ D ++ L W PP G ++ Y VQK D T W
Sbjct: 16941 ASIEIVTLDKPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDV 17000
Query: 1115 VLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKA 1174
V RT V +L G Y FR+F++N G S A +P+ P Y+ P
Sbjct: 17001 VSATVARTTLKVTKLKTGTEYQFRIFAENRYGQS--FALESDPIVAQYP---YKEPGPPG 17055
Query: 1175 LDFSEAPSFTQPLV--NRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSK 1232
F+ A S ++ + V G + ++ + + I W K + D +F+ +
Sbjct: 17056 TPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNL 17115
Query: 1233 QGVLTLEIR 1241
+ + E R
Sbjct: 17116 EEGIEYEFR 17124
Score = 224 bits (571), Expect = 4e-58
Identities = 156/532 (29%), Positives = 231/532 (43%), Gaps = 44/532 (8%)
Query: 622 ACNLSAKLHFME--VKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAP 679
A N+ + E +I+ V R E P + L + T+ + AG LRL V +SG P P
Sbjct: 23047 AVNVKGMSEYSESIAEIEPVERIEIPDLEL--ADDLKKTVTIRAGASLRLMVSVSGRPPP 23104
Query: 680 TVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVE 739
+ W K QG + R ++TT+ S+ V+
Sbjct: 23105 VITWSK---QG----------------------------IDLASRAIIDTTESYSLLIVD 23133
Query: 740 GAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDG 799
+ D G YT+ +N G+ + VKV D P + K+ V DS T+ WE P DG
Sbjct: 23134 KVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDG 23193
Query: 800 GQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSP 859
G P+ YI+E K++ + R + + + ++EG +Y RV N G+ P
Sbjct: 23194 GAPVNNYIVE-KREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCE 23252
Query: 860 ASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEW--- 916
S + P P L V DV+ +TV+L W P G L GY +E C G W
Sbjct: 23253 TSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKV 23312
Query: 917 VAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLP 976
V + EHT V L G + LFR+RA N G P T VTVQ++ P + L
Sbjct: 23313 VTLKPTVLEHT---VTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLS 23369
Query: 977 RHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPL-AGEEVSIRNSPTDTILFIRAA 1035
++TI G PV L+IP G+P P +W G L E V++ L IR
Sbjct: 23370 TMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRET 23429
Query: 1036 RRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQ-DLRVTDAWGLNVALEWKPPQDVGN 1094
+G Y + ++ T+ + ++DKP PP +++ + ++ + W+PP+ G
Sbjct: 23430 TIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEPPELDGG 23489
Query: 1095 TELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVG 1146
L GY V++ D W V E R+ L GN Y FRV + N G
Sbjct: 23490 APLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFG 23541
Score = 220 bits (561), Expect = 6e-57
Identities = 171/617 (27%), Positives = 257/617 (41%), Gaps = 63/617 (10%)
Query: 575 GVWLKNGKELVPDSRIKVSHI--GRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFM 632
G W K E +R V+ + G +K + + A + D +C ++
Sbjct: 21926 GDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGD--------SCEVTGT---- 21973
Query: 633 EVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNK 692
I V R P++ +D T VV AG +RL + G P PT +W K
Sbjct: 21974 ---IKAVDRLTAPELDIDA--NFKQTHVVRAGASIRLFIAYQGRPTPTAVWSK------- 22021
Query: 693 APARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVT 752
PD+ R + TT S TVE + D G YT+T
Sbjct: 22022 ------PDS------------------NLSLRADIHTTDSFSTLTVENCNRNDAGKYTLT 22057
Query: 753 VKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKK 812
V+N G + TVKV+D P P +V S T+ W+ P DGG I Y++E+++
Sbjct: 22058 VENNSGSKSITFTVKVLDTPGPPGPITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKRE 22117
Query: 813 KKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSE 872
W ++ +++ + + EGV Y RV AVN G+ P +P + P+
Sbjct: 22118 ASRRSWQVISEKCTRQI-FKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAP 22176
Query: 873 PTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVK 932
P L V D S ++ L W P+ G + GY +E +G WV A G T+ + V+
Sbjct: 22177 PRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEA--GHTKQLTFTVE 22234
Query: 933 DLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVN 992
L FRV+A N AG P V ++E P L Q I K G P
Sbjct: 22235 RLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFT 22294
Query: 993 LLIPFQGKPRPQVTWTKEGQPL-AGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIEN 1051
+ +P G+P P+VTW E L + VSI + T L ++ + R SG Y +T+
Sbjct: 22295 IDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTA 22354
Query: 1052 MEDKATLVLQVVDKPSP-PQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTM 1110
++ + V+ +P P + V+ + L W P+D G TE+ Y V+K + T
Sbjct: 22355 GVKTFSVTVVVIGRPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTT 22414
Query: 1111 EWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFS---DRAATTKEPVFIP-----R 1162
W V +RT V L Y FRV S+N G S + A E F+P R
Sbjct: 22415 AWQLVNSSVKRTQIKVTHLTKYMEYSFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPTR 22474
Query: 1163 PGITYEPPNYKALDFSE 1179
P + + N ++ + E
Sbjct: 22475 PEVYHVSANAMSIRWEE 22491
Score = 219 bits (559), Expect = 1e-56
Identities = 172/604 (28%), Positives = 278/604 (46%), Gaps = 64/604 (10%)
Query: 577 WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKI 636
W+K +EL +R+++ L++ D D +Y + A S ++ VK+
Sbjct: 16205 WIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVN---VKV 16261
Query: 637 DFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPAR 696
LD PG P+ VV++G ++ + T+ W+ + G
Sbjct: 16262 ------------LDRPGP-PEGPVVISG--------VTAEKC-TLAWKPPLQDGGS---- 16295
Query: 697 PAPDAPEDTGDSDEWVFDKK---LLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTV 753
D ++ +++ L T V+T + +EG +E + +
Sbjct: 16296 ----------DIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEG----NEYTFRIMA 16341
Query: 754 KNPVG-----EDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYIL 808
N G E + + VPDAP AP+++ V +DS V WE PA DGG ILGY+L
Sbjct: 16342 VNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPASDGGSEILGYVL 16401
Query: 809 ERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPAS---QPFM 865
E++ K+ RW R + LI EL +IE YE RV A NA G+S PSP S +
Sbjct: 16402 EKRDKEGIRWTRCHKRLIGELRLRVTGLIENHDYEFRVSAENAAGLSEPSPPSAYQKACD 16461
Query: 866 PIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAAL--QGL 923
PI P P + V D++ ++V L W P G + GY VE C EW G+
Sbjct: 16462 PIYKPGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGI 16521
Query: 924 TEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTI 983
+ T+I V+ L FR+ A N AG G P+ V+E L+ P + L LR+ I
Sbjct: 16522 NK-TNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDLELRKII 16580
Query: 984 QKKVGEPVNLLIPFQGKPRPQVTWTK-EGQPLAGEEVSIRNSPTDTILFIRAARRVHSGT 1042
+ G + L +P +G+P P+V W K +G+ + + +S T +L R SG
Sbjct: 16581 NIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLVL--DNVNRYDSGK 16638
Query: 1043 YQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTV 1102
Y +T+ + A + ++V+D PSPP +L+VT+ +V++ W+PP G +++ Y V
Sbjct: 16639 YTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIV 16698
Query: 1103 QKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPV---F 1159
+K + + V+ + + + +L G YYFRV ++N G A T +P+
Sbjct: 16699 EKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIG-LPAQTADPIKVAE 16757
Query: 1160 IPRP 1163
+P+P
Sbjct: 16758 VPQP 16761
Score = 219 bits (557), Expect = 2e-56
Identities = 152/493 (30%), Positives = 234/493 (47%), Gaps = 38/493 (7%)
Query: 700 DAPEDTGDSD--EWVFDKKLLCETEGRVRVETTKDRSIFT----VEGAEKEDEGVYTVTV 753
D PED G + ++ +K CET+ V +T ++ T V + +E ++ V
Sbjct: 11946 DPPEDDGGCEIQNYILEK---CETKRMVW--STYSATVLTPGTTVTRLIEGNEYIFRVRA 12000
Query: 754 KNPVGEDQVNLTVKVI-----DVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYIL 808
+N +G + VI D P P P+++ V ++ TV W PP YDGG+ I GY L
Sbjct: 12001 ENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFL 12060
Query: 809 ERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM--- 865
E+K+K S RW+ +N I E + + ++ Y+ RV A N IG+ PS S+P +
Sbjct: 12061 EKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKD 12120
Query: 866 PIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCP--------EGCSEWV 917
PI PP PT+ V D + +++L W P G + GY VE P EG
Sbjct: 12121 PIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCN 12180
Query: 918 AALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPR 977
AA Q + + V L FRV A N G G P E + +EIL+ P + L
Sbjct: 12181 AAAQLVRK--EFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEPPEIDLDA 12238
Query: 978 HLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARR 1037
+R+ + + G P+ L +G+P P+VTW K G + + T L I + R
Sbjct: 12239 SMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDTMAFLVIPNSTR 12298
Query: 1038 VHSGTYQVTVRIENMEDKATLV-LQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTE 1096
SG Y +T+ + +KA V ++V+D P P DL+V+D + + W PP++ G ++
Sbjct: 12299 DDSGKYSLTL-VNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQ 12357
Query: 1097 LWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKE 1156
+ Y V+K + W TV ++T V L+ GN YYFRV + N G
Sbjct: 12358 VTHYIVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYG-------PGV 12410
Query: 1157 PVFIPRPGITYEP 1169
P +P+P + +P
Sbjct: 12411 PTDVPKPVLASDP 12423
Score = 218 bits (554), Expect = 4e-56
Identities = 174/627 (27%), Positives = 269/627 (42%), Gaps = 72/627 (11%)
Query: 573 VRGV------WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLS 626
+RGV W +G E+ D V LTI + D +Y A + +
Sbjct: 11162 IRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKT 11221
Query: 627 AKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKA 686
+H LD PG I + LDV T+ WQ
Sbjct: 11222 VAVHLTV---------------LDVPGPPTGPINI-------LDVT---PEHMTISWQP- 11255
Query: 687 ITQGNKAPARPAPDAPEDTGDSD--EWVFDKK-LLCETEGRVRVETTKDRSIFTVEGAEK 743
P+D G S ++ +K+ +T G V ++K + + +K
Sbjct: 11256 ---------------PKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTK--LKIPHLQK 11298
Query: 744 EDEGVYTVTVKNPVG-----EDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYD 798
E V+ V +N +G + + P P P ++++ E++ TV W P D
Sbjct: 11299 GCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWTLPKSD 11358
Query: 799 GGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPS 858
GG PI GY +ER++ +W+R+N I +L + EG YE RV+A N G+S+PS
Sbjct: 11359 GGSPITGYYMERREVTG-KWVRVNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPS 11417
Query: 859 PASQPFM---PIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSE 915
P+S P PI PP P + ++D S T L W P G + GY VE G ++
Sbjct: 11418 PSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQ 11477
Query: 916 WVAALQG-LTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQ 974
W + L + V L G FR++A N+ G G P E V ++IL P ++
Sbjct: 11478 WNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVE 11537
Query: 975 LPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEE-VSIRNSPTDTILFIR 1033
L R I +VG+ + +L +G+P P +TWTKEG+ L E+ V + L I+
Sbjct: 11538 LDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIK 11597
Query: 1034 AARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVG 1093
A R G Y ++ + + + + ++ V+D+P P Q+L+VT+ N + W+ P D G
Sbjct: 11598 EAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKENCTISWENPLDNG 11657
Query: 1094 NTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAAT 1153
+E+ + V+ W V + + L+ N YYFRV ++N VG
Sbjct: 11658 GSEITNFIVEYRKPNQKGWSIVASDVTK-RLIKANLLANNEYYFRVCAENKVGVGP-TIE 11715
Query: 1154 TKEPVF----IPRPGITYEPPNYKALD 1176
TK P+ I RPG EP N D
Sbjct: 11716 TKTPILAINPIDRPG---EPENLHIAD 11739
Score = 218 bits (554), Expect = 4e-56
Identities = 153/548 (27%), Positives = 243/548 (44%), Gaps = 49/548 (8%)
Query: 633 EVKIDFVPRQ--EPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQG 690
E+K P++ EPP+I LD R ++V AG +RL + G PAP V W+K G
Sbjct: 12218 ELKEAIKPKEILEPPEIDLDASMR--KLVIVRAGCPIRLFAIVRGRPAPKVTWRKV---G 12272
Query: 691 NKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYT 750
R +V+ + + + ++D G Y+
Sbjct: 12273 IDNVVRKG---------------------------QVDLVDTMAFLVIPNSTRDDSGKYS 12305
Query: 751 VTVKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILER 810
+T+ NP GE V + V+V+D P + K+S+V + SC V W PP DGG + YI+E+
Sbjct: 12306 LTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEK 12365
Query: 811 KKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PI 867
++ W + + +++ S ++ G Y RV AVN G P+ +P + P+
Sbjct: 12366 READRKTWSTVTPE-VKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPL 12424
Query: 868 GPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEG--CSEWVAALQGLTE 925
P P L V +++ + +L W PP R G +DGY Y E W + +
Sbjct: 12425 SEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTE--YSVVK 12482
Query: 926 HTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQK 985
S++V L G + FRV A N G P +E L P++ +P + I
Sbjct: 12483 DLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMP----EQITI 12538
Query: 986 KVGEPVNLLIPFQGKPRPQVTWTK-EGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQ 1044
K G+ + + GKP P W K E + + +++ + + +IL I+ R SG Y
Sbjct: 12539 KAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYS 12598
Query: 1045 VTVRIENMEDKATLVLQVVDKPSPPQD-LRVTDAWGLNVALEWKPPQDVGNTELWGYTVQ 1103
+T + D + + V+D P PPQ ++D +L W P + G + + Y V+
Sbjct: 12599 LTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSLSWHIPLEDGGSNITNYIVE 12658
Query: 1104 KADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRP 1163
K D +W T L +T C V +LI G Y FRV ++N G S+ + K P
Sbjct: 12659 KCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPF- 12717
Query: 1164 GITYEPPN 1171
G+ EP N
Sbjct: 12718 GVPSEPKN 12725
Score = 217 bits (552), Expect = 7e-56
Identities = 151/520 (29%), Positives = 234/520 (45%), Gaps = 42/520 (8%)
Query: 636 IDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPA 695
I+ R P + LD R D IVV AG +R+ +SG P PTV W
Sbjct: 10141 IEMKDRLVSPDLQLDASVR--DRIVVHAGGVIRIIAYVSGKPPPTVTWNMN--------E 10190
Query: 696 RPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKN 755
R P +ETT S ++ ++ +GVY++ KN
Sbjct: 10191 RTLPQ-----------------------EATIETTAISSSMVIKNCQRSHQGVYSLLAKN 10227
Query: 756 PVGEDQVNLTVKVIDVPDAPAAPKIS-NVGEDSCTVQWEPPAYDGGQPILGYILERKKKK 814
GE + + V V+DVP P ++ N+ +SC + W P DGG PI Y++E+++
Sbjct: 10228 EAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESD 10287
Query: 815 SYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PIGPPS 871
W + + + ++ + + +I+G Y R+ A N+IGM S+ + PI P
Sbjct: 10288 RRAWTPVTYTVTRQ-NATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPE 10346
Query: 872 EPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILV 931
P L V++V+ TV+L W PP+ G + Y +E G ++ V
Sbjct: 10347 RPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTV 10406
Query: 932 KDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPV 991
K L G +RV A N+ G G P T+P+T ++ L P L L + TI +VGE
Sbjct: 10407 KGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHLDFRDKLTI--RVGEAF 10464
Query: 992 NLLIPFQGKPRPQVTWTK-EGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIE 1050
L + GKP+P+V+W K E L + I+ +P L A+R SG Y V V
Sbjct: 10465 ALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENS 10524
Query: 1051 NMEDKATLVLQVVDKPSPPQD-LRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKT 1109
K + VVD+P PP + + + + WKPP D G +++ Y ++K +
Sbjct: 10525 TGSRKGFCQVNVVDRPGPPVGPVSFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGK 10584
Query: 1110 MEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSD 1149
W V +T C V +L+ G Y FR+ ++N+ G SD
Sbjct: 10585 DVWMPVTSASAKTTCKVSKLLEGKDYIFRIHAENLYGISD 10624
Score = 214 bits (546), Expect = 3e-55
Identities = 169/608 (27%), Positives = 283/608 (46%), Gaps = 58/608 (9%)
Query: 643 EPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAP 702
E P+I LD R +++ AG +++ +P G P PTV W+K
Sbjct: 20895 EAPEIDLDVALRT--SVIAKAGEDVQVLIPFKGRPPPTVTWRK----------------- 20935
Query: 703 EDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQV 762
D+K L ++ R +E T S+ T+ + D G Y +T++N VGE +
Sbjct: 20936 -----------DEKNL-GSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKS 20983
Query: 763 N-LTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRL 821
+ ++VKV+D P A ++ +V + T+ W+PP DGG PI+ Y++E++ W +
Sbjct: 20984 STVSVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVV 21043
Query: 822 NFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDV 881
+ S + + E + RV A N IG+ P ++P P+ L+++D
Sbjct: 21044 SHKC-SSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDS 21102
Query: 882 SDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLL 941
+ T+V L W P+ G + Y VE +G W A G+++ I V L + L
Sbjct: 21103 TKTSVILSWTKPDFDGGSVITEYVVERKGKGEQTWSHA--GISKTCEIEVSQLKEQSVLE 21160
Query: 942 FRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKP 1001
FRV A N G PVT P+TV+E++ P + L + ++G V+L +P++GKP
Sbjct: 21161 FRVFAKNEKGLSDPVTIG-PITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKP 21219
Query: 1002 RPQVTWTKEGQPLAGEEVSIRNSPTDT--ILFIRAARRVHSGTYQVTVRIENMEDKATLV 1059
+P ++W K+G PL E +R S T+ L I+ A++ H G Y TV ++N + +
Sbjct: 21220 KPSISWLKDGLPLKESEF-VRFSKTENKITLSIKNAKKEHGGKY--TVILDNAVCRIAVP 21276
Query: 1060 LQVV--DKPSPPQ-DLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVL 1116
+ V+ PS P+ +R + +V L W P+D G E+ Y+++K + W V
Sbjct: 21277 ITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTNWKMVC 21336
Query: 1117 EHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATT----KEPVFIPRPGITYEPPNY 1172
RT VP L+ Y FRV ++N G S ++ K IP P +P Y
Sbjct: 21337 SSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGP--PGKPVIY 21394
Query: 1173 KALDFSEAPSFTQPLVN-RSVIAGY-------TAMLCCAVRGSPKPKISWFKNGLDLGED 1224
+ ++ P+ + S + G+ ++L V SP + GL G D
Sbjct: 21395 NVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLD 21454
Query: 1225 ARFRMFSK 1232
+FR++++
Sbjct: 21455 YQFRVYAE 21462
Score = 213 bits (543), Expect = 7e-55
Identities = 137/438 (31%), Positives = 210/438 (47%), Gaps = 12/438 (2%)
Query: 732 DRSIFTVEGAEKEDEGVYTVTVKNPVG-----EDQVNLTVKVIDVPDAPAAPKISNVGED 786
+ I T K +E ++ V N G E + P P P+++ + ++
Sbjct: 20649 EECIITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKN 20708
Query: 787 SCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRV 846
S TV W P DGG I GY LE++ KKS W ++ + I++ + + E Y+ RV
Sbjct: 20709 SMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRV 20768
Query: 847 YAVNAIGM---SRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDG 903
AVNA G S PS + PI PP P + + D + ++++L W P G + G
Sbjct: 20769 CAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTG 20828
Query: 904 YSVEYCPEGCSEWVA-ALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPV 962
Y VE EW + +G T +V +L G FRV A N AG G P+ EPV
Sbjct: 20829 YVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPV 20888
Query: 963 TVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGE-EVSI 1021
++IL+ P + L LR ++ K GE V +LIPF+G+P P VTW K+ + L + SI
Sbjct: 20889 QAKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSI 20948
Query: 1022 RNSPTDTILFIRAARRVHSGTYQVTVRIENMEDK-ATLVLQVVDKPSPPQDLRVTDAWGL 1080
N+ + ++L I R +G Y +T+ E K +T+ ++V+D P+ Q L+V
Sbjct: 20949 ENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRG 21008
Query: 1081 NVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVF 1140
V L W PP G + + Y ++K D W V T + +L ++FRV
Sbjct: 21009 TVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVL 21068
Query: 1141 SQNMVGFSDRAATTKEPV 1158
++N +G + TT EPV
Sbjct: 21069 AENEIGIGEPCETT-EPV 21085
Score = 212 bits (540), Expect = 2e-54
Identities = 170/605 (28%), Positives = 264/605 (43%), Gaps = 59/605 (9%)
Query: 641 RQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPD 700
R PP+I LD R + + A LRL VPI G PAP V W +
Sbjct: 15482 RMLPPEIELDADLR--KVVTIRACCTLRLFVPIKGRPAPEVKWAR--------------- 15524
Query: 701 APEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGED 760
D G+S + + +E+T ++ V + D G Y +TV+N G
Sbjct: 15525 ---DHGESLD-------------KASIESTSSYTLLIVGNVNRFDSGKYILTVENSSGSK 15568
Query: 761 QVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKK--KKSYRW 818
+ V+V+D P P K+ V + S T+ W+PP DGG I YI+E+++ +K+Y
Sbjct: 15569 SAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVEKRESTRKAYST 15628
Query: 819 MRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAV 878
+ N + S + ++ EG Y RV A N G+ P+ ++ P P + +
Sbjct: 15629 VATN---CHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKASERPLPPGKITL 15685
Query: 879 EDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGA 938
DV+ +VSL W PE G + GY VE +G +W A + T + L G
Sbjct: 15686 MDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKW--ATCATVKVTEATITGLIQGE 15743
Query: 939 RLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQ 998
FRV A N G P + PV ++++ P +L L T GE + + +PF
Sbjct: 15744 EYSFRVSAQNEKGISDPRQLSVPVIAKDLVIPPAFKL---LFNTFTVLAGEDLKVDVPFI 15800
Query: 999 GKPRPQVTWTKEGQPL-AGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKAT 1057
G+P P VTW K+ PL V+ ++ +++L I+ A R G Y V + E T
Sbjct: 15801 GRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIET 15860
Query: 1058 LVLQVVDKPSPPQ-DLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVL 1116
L + V+DKP PP +++ + ++ L W PP+ G + + Y V+K D T W V
Sbjct: 15861 LNVIVLDKPGPPTGPVKMDEVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTWQIVS 15920
Query: 1117 EHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALD 1176
RT L G Y FR+ ++N G S EP P PP +
Sbjct: 15921 ATVARTTIKACRLKTGCEYQFRIAAENRYGKS--TYLNSEPTVAQYPFKVPGPPGTPVVT 15978
Query: 1177 FSEAPS----FTQPLVN-RSVIAGY-------TAMLCCAVRGSPKPKISWFKNGLDLGED 1224
S S + +P+ + S + GY ++L + +P P+ + GL+ G +
Sbjct: 15979 LSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGVE 16038
Query: 1225 ARFRM 1229
FR+
Sbjct: 16039 YEFRV 16043
Score = 211 bits (537), Expect = 4e-54
Identities = 158/561 (28%), Positives = 244/561 (43%), Gaps = 48/561 (8%)
Query: 644 PPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPE 703
PP+ LD R T+++ AG +RL VP+ G P P + W K P + +
Sbjct: 13318 PPEGELDADLR--KTLILRAGVTMRLYVPVKGRPPPKITWSK-----------PNVNLRD 13364
Query: 704 DTG-DSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQV 762
G D FD L C E K D G Y +T++N G+ +
Sbjct: 13365 RIGLDIKSTDFDTFLRC-------------------ENVNKYDAGKYILTLENSCGKKEY 13405
Query: 763 NLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLN 822
+ VKV+D P P + + +DS V WEPP DGG PI+ Y+++++ + W +
Sbjct: 13406 TIVVKVLDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVT 13465
Query: 823 FDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVS 882
+ + S + EG Y RV+A N G+ P P L V VS
Sbjct: 13466 TE-CSKTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVVDLKVRSVS 13524
Query: 883 DTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLF 942
++ S+ W+ P G + GY V++ E ++W ++ L+ S KDL G F
Sbjct: 13525 KSSCSIGWKKPHSDGGSRIIGYVVDFLTEE-NKWQRVMKSLSLQYS--AKDLTEGKEYTF 13581
Query: 943 RVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPR 1002
RV A N G G P T V ++ + P L L K L IP +GKP
Sbjct: 13582 RVSAENENGEGTPSEIT--VVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPA 13639
Query: 1003 PQVTWTKEGQPLAGE-EVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQ 1061
P V+W K PLA + VS+ +S +T L + ++ +G Y +T++ + T+ ++
Sbjct: 13640 PSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIK 13699
Query: 1062 VVDKPS-PPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYR 1120
VV KP P ++ + + L+W PP+D G +E+ Y ++K D +W T +
Sbjct: 13700 VVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCASAVQ 13759
Query: 1121 RTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRP-GITYEPPNYKALDF-- 1177
+T V L G Y FRV ++N G + EP+ P + PP +D
Sbjct: 13760 KTTFRVTRLHEGMEYTFRVSAENKYGVGE--GLKSEPIVARHPFDVPDAPPPPNIVDVRH 13817
Query: 1178 -SEAPSFTQP-LVNRSVIAGY 1196
S + ++T P S I GY
Sbjct: 13818 DSVSLTWTDPKKTGGSPITGY 13838
Score = 211 bits (537), Expect = 4e-54
Identities = 149/517 (28%), Positives = 234/517 (45%), Gaps = 47/517 (9%)
Query: 636 IDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPA 695
++ V R+ P LD R T+VV AG +R+ VPI G PAP V W K
Sbjct: 14393 VEIVEREMAPDFELDAELR--RTLVVRAGLSIRIFVPIKGRPAPEVTWTK---------- 14440
Query: 696 RPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKN 755
D+ + R +E T+ ++ + + D G + +T++N
Sbjct: 14441 -----------DN----------INLKNRANIENTESFTLLIIPECNRYDTGKFVMTIEN 14479
Query: 756 PVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKK--K 813
P G+ + V+V+D P + +++ +DS T+ W+ P DGG I YI+E+++ +
Sbjct: 14480 PAGKKSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATR 14539
Query: 814 KSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEP 873
KSY + +++ + EG Y RV A N G+ P+ ++P PS P
Sbjct: 14540 KSYSTATTK---CHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPP 14596
Query: 874 THLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEW--VAALQGLTEHTSILV 931
L + D++ +TVSL W P+ G + GY +E +G +W + ++GL +V
Sbjct: 14597 DSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQWTHITTVKGL----ECVV 14652
Query: 932 KDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPV 991
++L G F+V A N AG AP + PV V+E P L L ++ + K G+ +
Sbjct: 14653 RNLTEGEEYTFQVMAVNSAGRSAP-RESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNI 14711
Query: 992 NLLIPFQGKPRPQVTWTKEGQPL-AGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIE 1050
+ IP G+P+P VTW K Q L + V+ + T TIL I R SG Y +T R
Sbjct: 14712 KVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNI 14771
Query: 1051 NMEDKATLVLQVVDKPSPPQ-DLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKT 1109
E + +QV D P PP ++ + V W PP++ G + Y V+ +
Sbjct: 14772 VGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDS 14831
Query: 1110 MEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVG 1146
W + RT L G Y FRV +QN G
Sbjct: 14832 TTWVELATTVIRTTYKATRLTTGLEYQFRVKAQNRYG 14868
Score = 209 bits (531), Expect = 2e-53
Identities = 164/608 (26%), Positives = 257/608 (42%), Gaps = 65/608 (10%)
Query: 577 WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKI 636
W K E+V S + V L I DVT D YS E S+ ++K+
Sbjct: 12560 WKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAEN-----SSGTDTQKIKV 12614
Query: 637 DFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKA-ITQGNKAPA 695
+ PP+ D I D + + G I +K +++G
Sbjct: 12615 VVMDAPGPPQPPFD----ISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRG----- 12665
Query: 696 RPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKN 755
+WV + +T RV + G E ++ V +N
Sbjct: 12666 --------------DWVTALASVTKTSCRVGK---------LIPGQEY----IFRVRAEN 12698
Query: 756 PVGEDQVNLTVKVI-----DVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILER 810
G + + K++ VP P +++ V +D V W+ P DGG PI+GY++ER
Sbjct: 12699 RFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIER 12758
Query: 811 KKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQ---PFMPI 867
K++ S W++ N L++ + ++EG+ Y R+YA+N G S PS ++ MP+
Sbjct: 12759 KERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPV 12818
Query: 868 GPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTE-- 925
PP +P V DV+ +TVSL W P+ G + GY VE C +WV +
Sbjct: 12819 DPPGKP---EVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIP 12875
Query: 926 HTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQK 985
L A+ FR A P ++PVT+ PR+ L ++ +
Sbjct: 12876 QEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVAMKSLLTV 12935
Query: 986 KVGEPVNLLIPFQGKPRPQVTWTKEG---QPLAGEEVSIRNSPTDTILFIRAARRVHSGT 1042
K G V L GKP P V+W K+G +P G +++++ + LF + R SG
Sbjct: 12936 KAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELF--SVNRKDSGD 12993
Query: 1043 YQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTV 1102
Y +T + AT+ L+V+DKP PP +++ + L W+PP + G +E+ Y V
Sbjct: 12994 YTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIV 13053
Query: 1103 QKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPR 1162
K + W V T C V +LI G+ Y FR+ ++N G D T EP
Sbjct: 13054 DKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFT--EPAIAKN 13111
Query: 1163 PGITYEPP 1170
P Y+PP
Sbjct: 13112 P---YDPP 13116
Score = 207 bits (526), Expect = 7e-53
Identities = 139/404 (34%), Positives = 194/404 (48%), Gaps = 13/404 (3%)
Query: 771 VPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELS 830
VPDAP P ++ V +DS V W P +DGG+PI YILE+++ S RW R+ D I +
Sbjct: 10639 VPDAPDQPIVTEVTKDSALVTWNKP-HDGGKPITNYILEKRETMSKRWARVTKDPIHPYT 10697
Query: 831 H-EARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PIGPPSEPTHLAVEDVSDTTV 886
++EG YE RV A N IG+ PSP S+P PI PS P + D + +V
Sbjct: 10698 KFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSV 10757
Query: 887 SLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAA--LQGLTEHTSILVKDLPTGARLLFRV 944
L W+PP G + GY VEY G EW A T V L G FRV
Sbjct: 10758 DLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRV 10817
Query: 945 RAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQ 1004
A N AG P EPV V++ L+ P L L ++ + KVG+ + L +G P P+
Sbjct: 10818 LAVNAAGESDPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPK 10877
Query: 1005 VTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVD 1064
VTW KE + A + I +P + L IR A G Y +TV ++ + V+D
Sbjct: 10878 VTWKKEDRD-APTKARIDVTPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLD 10936
Query: 1065 KPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHC 1124
KP PP+DL V++ + L WK P D G + + Y V++ D + +W + ++
Sbjct: 10937 KPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSH 10996
Query: 1125 VVPELIIGNGYYFRVFSQNMVGFSDRAATTK-----EPVFIPRP 1163
L GN Y FRV ++N G T K +P+ P P
Sbjct: 10997 FAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGP 11040
Score = 206 bits (524), Expect = 1e-52
Identities = 169/608 (27%), Positives = 260/608 (42%), Gaps = 74/608 (12%)
Query: 577 WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFV---PEGFACNLSAKLHFME 633
W K+GKEL +++++ L D T D Y+ P GFA H
Sbjct: 15123 WSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGGFA------KHIFN 15176
Query: 634 VKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKA 693
VK+ LD PG P G A T + + K
Sbjct: 15177 VKV------------LDRPG------------------PPEGPLAVTEVTSE------KC 15200
Query: 694 PARPAPDAPEDTGDSDEWVFDKK---LLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYT 750
P + D ++ K+ L T V+ TK + ++G +E ++
Sbjct: 15201 VLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKG----NEYIFR 15256
Query: 751 VTVKNPVG-----EDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILG 805
V N G E + L V PD P P+++ + +DS V W P DGG I+
Sbjct: 15257 VMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIIN 15316
Query: 806 YILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM 865
YI+ER+ K RW++ N + +L ++ + EG YE R+ A NA G+S PSP S PF
Sbjct: 15317 YIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTS-PFY 15375
Query: 866 PI-------GPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEW-- 916
GPP P V D S +++S+ W P G + GY VE EW
Sbjct: 15376 KACDTVFKPGPPGNP---RVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQI 15432
Query: 917 VAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLP 976
V GL + TS + L R+ A N G G P ++ + P ++L
Sbjct: 15433 VTPPAGL-KATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEIELD 15491
Query: 977 RHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKE-GQPLAGEEVSIRNSPTDTILFIRAA 1035
LR+ + + + L +P +G+P P+V W ++ G+ L ++ SI ++ + T+L +
Sbjct: 15492 ADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDHGESL--DKASIESTSSYTLLIVGNV 15549
Query: 1036 RRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNT 1095
R SG Y +TV + A + ++V+D P PPQDL+V + +V L W PP G +
Sbjct: 15550 NRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGS 15609
Query: 1096 ELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTK 1155
++ Y V+K + + TV + +T V +L G YYFRV ++N G A T +
Sbjct: 15610 KIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAE 15669
Query: 1156 EPVFIPRP 1163
RP
Sbjct: 15670 SVKASERP 15677
Score = 205 bits (522), Expect = 2e-52
Identities = 166/590 (28%), Positives = 260/590 (44%), Gaps = 57/590 (9%)
Query: 577 WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKI 636
W K+G L P IK++ + L + V D DY+ E + + SA + ++K+
Sbjct: 12957 WKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATI---KLKV 13013
Query: 637 DFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPAR 696
LD PG P V + NK+ D + + W+ + G
Sbjct: 13014 ------------LDKPG--PPASVKI--NKMYSDRAM-------LSWEPPLEDGGS---- 13046
Query: 697 PAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNP 756
+ ++ DK+ +V T + +VE + E + + +N
Sbjct: 13047 ----------EITNYIVDKRETSRPNW-AQVSATVPITSCSVEKLIEGHEYQFRICAENK 13095
Query: 757 VGEDQVNLTVKVI-----DVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERK 811
G T I D P P ISN+ +D TV W+PPA DGG PI GY+LE++
Sbjct: 13096 YGVGDPVFTEPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKR 13155
Query: 812 KKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQ------PFM 865
+ ++ W ++N I E + +A + EG YE RV A+N G +PS AS+ P
Sbjct: 13156 ETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQY 13215
Query: 866 PIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAA-LQGLT 924
P GPP+ P V D + ++VSL W P G + GY VE WV L
Sbjct: 13216 PPGPPAFP---KVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNL 13272
Query: 925 EHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQ 984
+ T V L + FRV A N G P + ++IL P +L LR+T+
Sbjct: 13273 QKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLI 13332
Query: 985 KKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGE-EVSIRNSPTDTILFIRAARRVHSGTY 1043
+ G + L +P +G+P P++TW+K L + I+++ DT L + +G Y
Sbjct: 13333 LRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKY 13392
Query: 1044 QVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQ 1103
+T+ + + T+V++V+D P PP ++ V + + + W+PP G + + Y VQ
Sbjct: 13393 ILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQ 13452
Query: 1104 KADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAAT 1153
K D + W TV +T V L G Y+FRVF++N G D T
Sbjct: 13453 KRDAERKSWSTVTTECSKTSFRVANLEEGKSYFFRVFAENEYGIGDPGET 13502
Score = 204 bits (519), Expect = 4e-52
Identities = 155/574 (27%), Positives = 256/574 (44%), Gaps = 43/574 (7%)
Query: 632 MEVKIDFVPRQEPPKIHLDCPGRIPD---TIVVVAGNKL-----RLDVPISGDPAPTVIW 683
+++ + V R E K L P + + T V A N+L + V + P+P
Sbjct: 9074 LQITKEEVSRSEA-KTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPR-- 9130
Query: 684 QKAITQGNKAPARPAPDAPEDTGDSD--EWVFDKKLLCETEGR-VRVETTKDRSIFTVEG 740
A+T DAP D G S+ +V DK+ + V T + +
Sbjct: 9131 NLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWK 9190
Query: 741 AEKEDEGVYTVTVKNPVGEDQVNLTVKVI-----DVPDAPAAPKISNVGEDSCTVQWEPP 795
+ + V N G + KV+ +P P PK+ + S V W PP
Sbjct: 9191 LIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPP 9250
Query: 796 AYDGGQPILGYILERKKKKSYRWMRLNFDLIQELS-----HEARRMIEGVVYEMRVYAVN 850
+GG PI GY LE++++ S W R++ I ++ R++EGV Y+ R A+N
Sbjct: 9251 LDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAIN 9310
Query: 851 AIGMSRPSPASQPFM---PIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVE 907
A G+ PS S P + PI PP P+ V+D + +++SL W+PP + G + GY VE
Sbjct: 9311 AAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVE 9370
Query: 908 YCPEGCSEW--VAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQ 965
EG ++W V L +V +L + FRV+A N AG P TT +
Sbjct: 9371 MQEEGTTDWKRVNEPDKLITTCECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPAT 9430
Query: 966 EILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSP 1025
+I + P + + + + K G + + +G+P P+ +W +G+ + + + P
Sbjct: 9431 DIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIP 9490
Query: 1026 TD---------TILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTD 1076
D +++ I +R H+G Y +T + + + A ++V+D P PP+DL+V+D
Sbjct: 9491 EDAQLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDLKVSD 9550
Query: 1077 AWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYY 1136
+ L WK P D G + GY ++K W V T VVP+L+ Y+
Sbjct: 9551 ITRGSCRLSWKMPDDDGGDRIKGYVIEKRTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYF 9610
Query: 1137 FRVFSQNMVGFSD-----RAATTKEPVFIPRPGI 1165
FRV ++N G + T ++P++ P P I
Sbjct: 9611 FRVRAENRFGIGPPVETIQRTTARDPIYPPDPPI 9644
Score = 203 bits (516), Expect = 1e-51
Identities = 156/577 (27%), Positives = 241/577 (41%), Gaps = 75/577 (12%)
Query: 659 IVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLL 718
I+V+ G KL + VP P PTV W K D E
Sbjct: 8024 IIVIEGEKLSIPVPFRAVPVPTVSWHK---------------------DGKE-------- 8054
Query: 719 CETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAP 778
+ R+ ++ + V + + D G+YT+T++N +G ++ VKVI +P
Sbjct: 8055 VKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKDI 8114
Query: 779 KISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIE 838
K S++ + SC + WEPP +DGG PIL Y+LER++ ++ + +LS + +I
Sbjct: 8115 KASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPV-MSGENKLSWTVKDLIP 8173
Query: 839 GVVYEMRVYAVNAIGMSRPSPASQPFM---PIGPPSEPTHLAVEDVSDTTVSLKWRPPER 895
Y RV AVN +G P + P PP P + V + + +++ W+PP
Sbjct: 8174 NGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITWKPPLY 8233
Query: 896 VGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAP 955
G + GY +E +G W + L + K L G FRVRA N AG P
Sbjct: 8234 DGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTYTAKGLEEGKEYQFRVRAENAAGISEP 8293
Query: 956 VTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLA 1015
T P + + P++ L R +++ K G+ + L G P P +TW K+ +
Sbjct: 8294 SRATPPTKAVDPIDAPKVIL----RTSLEVKRGDEIALDASISGSPYPTITWIKDENVIV 8349
Query: 1016 GEEVSIRNSPT------------------------------DTILFIRAARRVHSGTYQV 1045
EE+ R +P ++ L +R + R G Y +
Sbjct: 8350 PEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMI 8409
Query: 1046 TVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKA 1105
V ++ KA + V+D P PP + D +V +W+PP D G +E+ YT++K
Sbjct: 8410 KVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCKWEPPLDDGGSEIINYTLEKK 8469
Query: 1106 D--KKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVG----FSDRAATTKEPVF 1159
D K EW V R V +LI G Y FRV ++N G + K+P F
Sbjct: 8470 DKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKPLVAKDP-F 8528
Query: 1160 IPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGY 1196
P P +P S + +P N S I GY
Sbjct: 8529 GP-PDAPDKPIVEDVTSNSMLVKWNEPKDNGSPILGY 8564
Score = 202 bits (514), Expect = 2e-51
Identities = 143/504 (28%), Positives = 223/504 (44%), Gaps = 23/504 (4%)
Query: 727 VETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGE----DQVNLTVKV-IDVPDAPAAPKIS 781
V T R++ V +E + + +N G D +TVK+ P P+ P ++
Sbjct: 20248 VSATVARTMMKVMKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVT 20307
Query: 782 NVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVV 841
NV +S TV W P +GG ++GY LE K + S W + N +I+ + + G++
Sbjct: 20308 NVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLI 20367
Query: 842 YEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGL 901
YE RVYA NA G+ +PS S+P + I P ++ + D+S +VSL W+ P G +
Sbjct: 20368 YEFRVYAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKI 20427
Query: 902 DGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGP-GAPVTTTE 960
GY VE W A T ++ L ++ FRV A N G P
Sbjct: 20428 TGYIVERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVG 20487
Query: 961 PVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPL-AGEEV 1019
P+T + P + LP + ++ + G V L GKP P + W K+ + L V
Sbjct: 20488 PITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALV 20547
Query: 1020 SIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPP-QDLRVTDAW 1078
+ N+ + I+ A R++SG Y++ +R AT+ +Q++DKP PP +
Sbjct: 20548 CVENTTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVT 20607
Query: 1079 GLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFR 1138
+ L W+PP D G ++ Y V+K + + W V EH ++I GN Y FR
Sbjct: 20608 AEKITLLWRPPADDGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFR 20667
Query: 1139 VFSQNMVGF-----SDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVN-RSV 1192
V + N G SD V PGI P K S +++P+ + S
Sbjct: 20668 VRAVNKYGIGEPLESDSVVAKNAFVTPGPPGI---PEVTKITKNSMTVVWSRPIADGGSD 20724
Query: 1193 IAGYTAMLCCAVRGSPKPKISWFK 1216
I+GY + K + WFK
Sbjct: 20725 ISGY------FLEKRDKKSLGWFK 20742
Score = 202 bits (513), Expect = 2e-51
Identities = 144/471 (30%), Positives = 207/471 (43%), Gaps = 23/471 (4%)
Query: 683 WQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAE 742
W+ + G + + T EW+ L + V +F V
Sbjct: 8450 WEPPLDDGGSEIINYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAEN 8509
Query: 743 KEDEGVYTVT----VKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYD 798
+ G V+ K+P G PDAP P + +V +S V+W P D
Sbjct: 8510 RFGPGPPCVSKPLVAKDPFGP------------PDAPDKPIVEDVTSNSMLVKWNEPK-D 8556
Query: 799 GGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPS 858
G PILGY LE+++ S W R+N L+ L ++EG+ Y RV A NA G + S
Sbjct: 8557 NGSPILGYWLEKREVNSTHWSRVNKSLLNALKANVDGLLEGLTYVFRVCAENAAGPGKFS 8616
Query: 859 PASQP---FMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSE 915
P S P PI PP P V D S TT+ L+W PP G G + GY V+ G +E
Sbjct: 8617 PPSDPKTAHDPISPPGPPIP-RVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNE 8675
Query: 916 WVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQL 975
W + + + VK++ GA RV A N AG G P T+PVTV E + P ++L
Sbjct: 8676 WSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGEGPP-GETQPVTVAEPQEPPAVEL 8734
Query: 976 PRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAA 1035
++ IQ G+ + + G+P P WTKE L + V I N T + L I+ A
Sbjct: 8735 DVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGTKSELIIKDA 8794
Query: 1036 RRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNT 1095
R G Y +T A ++V D P P DL+ L W P+D G +
Sbjct: 8795 LRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGS 8854
Query: 1096 ELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVG 1146
E+ G+ +++ D K W +E R+ C + L+ G Y FRV ++N G
Sbjct: 8855 EITGFIIERKDAKMHTWRQPIE-TERSKCDITGLLEGQEYKFRVIAKNKFG 8904
Score = 201 bits (512), Expect = 3e-51
Identities = 169/574 (29%), Positives = 245/574 (42%), Gaps = 58/574 (10%)
Query: 642 QEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDA 701
QEPP + LD + I ++AG LR+ ++G P PT +W K
Sbjct: 8727 QEPPAVELDVS--VKGGIQIMAGKTLRIPAVVTGRPVPTKVWTK---------------- 8768
Query: 702 PEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQ 761
+E DK RV ++ +S ++ A ++D G Y +T N G
Sbjct: 8769 -------EEGELDKD-------RVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKF 8814
Query: 762 VNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRL 821
V+V DVP K C + W P DGG I G+I+ERK K + W +
Sbjct: 8815 AAARVEVFDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFIIERKDAKMHTWRQ- 8873
Query: 822 NFDLIQELSH-EARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PIGPPSEPTHLA 877
+ E S + ++EG Y+ RV A N G P P + P+GPP+ P L
Sbjct: 8874 --PIETERSKCDITGLLEGQEYKFRVIAKNKFGCGPPVEIG-PILAVDPLGPPTSPERLT 8930
Query: 878 VEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTG 937
+ + +T++L W+ P G + GY +E ++ + L TS LV++L
Sbjct: 8931 YTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEH 8990
Query: 938 ARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLR-QTIQKKVGEPVNLLIP 996
FRV+A N G P V +Q+ P ++L +R TI+ K GEPV++
Sbjct: 8991 QMYEFRVKAVNEIGESEPSLPLN-VVIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPAD 9049
Query: 997 FQGKPRPQVTWTK---------EGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTV 1047
G P P++ W+K + + EEVS S T L I A R GTY VT
Sbjct: 9050 VTGLPMPKIEWSKNETVIEKPTDALQITKEEVS--RSEAKTELSIPKAVREDKGTYTVTA 9107
Query: 1048 RIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKAD- 1106
+ ++V D+PSPP++L VTD + L W P D G +E+ Y + K D
Sbjct: 9108 SNRLGSVFRNVHVEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDA 9167
Query: 1107 -KKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIP--RP 1163
+K EW V + +LI Y FRV + N G SD + K + P P
Sbjct: 9168 SRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLP 9227
Query: 1164 GITYEPPNYKALDFSEAPSFTQPLVN-RSVIAGY 1196
G +P S S+T PL N S I GY
Sbjct: 9228 GPPGKPKVLARTKGSMLVSWTPPLDNGGSPITGY 9261
Score = 201 bits (511), Expect = 4e-51
Identities = 166/600 (27%), Positives = 260/600 (43%), Gaps = 71/600 (11%)
Query: 577 WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKI 636
W K GK++ P +++ LTI T D +Y+ K+ ++V +
Sbjct: 14041 WSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATN---PFGTKVEHVKVTV 14097
Query: 637 DFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPAR 696
LDVP G P P I + KA
Sbjct: 14098 --------------------------------LDVP--GPPGPVEI---SNVSAEKATLT 14120
Query: 697 PAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKD----RSIFT--VEGAEKEDEGVYT 750
P + ++ +K+ ET + ++D R + T ++G +E ++
Sbjct: 14121 WTPPLEDGGSPIKSYILEKR---ETSRLLWTVVSEDIQSCRHVATKLIQG----NEYIFR 14173
Query: 751 VTVKNPVGEDQV--NLTVKVID---VPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILG 805
V+ N G+ + + VK++D P P P++SNV +++ TV W+ P DGG I G
Sbjct: 14174 VSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITG 14233
Query: 806 YILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM 865
Y +ER++KKS RW+R + +L + + EG YE RV A N G+ PS AS +
Sbjct: 14234 YHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVL 14293
Query: 866 ------PIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAA 919
P GPPS P V D + + SL W P G + GY VE+ G W+
Sbjct: 14294 MKDAAYPPGPPSNP---HVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKD 14350
Query: 920 LQGLT-EHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRH 978
G T +V DL T + FR+ A N AG G P + V + E P +L
Sbjct: 14351 TTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVIPD-VEIVEREMAPDFELDAE 14409
Query: 979 LRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRV 1038
LR+T+ + G + + +P +G+P P+VTWTK+ L +I N+ + T+L I R
Sbjct: 14410 LRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLK-NRANIENTESFTLLIIPECNRY 14468
Query: 1039 HSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELW 1098
+G + +T+ + + ++V+D P P +LR TD +V L W P G + +
Sbjct: 14469 DTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRIT 14528
Query: 1099 GYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPV 1158
Y V+K + + T + V L G Y+FRV ++N G + TT EPV
Sbjct: 14529 NYIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETT-EPV 14587
Score = 200 bits (508), Expect = 8e-51
Identities = 169/607 (27%), Positives = 252/607 (41%), Gaps = 59/607 (9%)
Query: 574 RGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFME 633
R W K+G E+ ++++ + L + D T Y+ + + + A++ +
Sbjct: 21617 RVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEI---K 21673
Query: 634 VKIDFVPRQEPPKIHLDCPGRI--PDTIVVVAGNKLRL--DVPISGDPAPTV--IWQKAI 687
VK+ D PG++ P + G K+ L D P++ AP I +K
Sbjct: 21674 VKVQ------------DTPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRE 21721
Query: 688 TQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEG 747
T +R A ED ++ + K L+ E + RV
Sbjct: 21722 T------SRLAWALIEDKCEAQSYTAIK-LINGNEYQFRVSA------------------ 21756
Query: 748 VYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYI 807
V V P+ D V ++ VPDAP P+ SN+ +S T+ W P DGG I YI
Sbjct: 21757 VNKFGVGRPLDSDPVVAQIQYT-VPDAPGIPEPSNITGNSITLTWARPESDGGSEIQQYI 21815
Query: 808 LERKKKKSYRWMR-LNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM- 865
LER++KKS RW++ ++ I E + + EG YE V A NA G+ S S+
Sbjct: 21816 LERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKC 21875
Query: 866 --PIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGL 923
P+ PP PT + V D S TTVSL+W P G + GY +E C +W
Sbjct: 21876 REPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEA 21935
Query: 924 TEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTI 983
T V DL G FRV A N AG G T + + L P L + + +QT
Sbjct: 21936 CVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTH 21995
Query: 984 QKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTY 1043
+ G + L I +QG+P P W+K L+ I + + + L + R +G Y
Sbjct: 21996 VVRAGASIRLFIAYQGRPTPTAVWSKPDSNLS-LRADIHTTDSFSTLTVENCNRNDAGKY 22054
Query: 1044 QVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQ 1103
+TV + T ++V+D P PP + D + L W P G + Y V+
Sbjct: 22055 TLTVENNSGSKSITFTVKVLDTPGPPGPITFKDVTRGSATLMWDAPLLDGGARIHHYVVE 22114
Query: 1104 KADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRP 1163
K + W + E R V +L G YYFRV + N G EP +P P
Sbjct: 22115 KREASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVG-------EPYEMPEP 22167
Query: 1164 GITYEPP 1170
+ E P
Sbjct: 22168 IVATEQP 22174
Score = 199 bits (507), Expect = 1e-50
Identities = 128/407 (31%), Positives = 195/407 (47%), Gaps = 14/407 (3%)
Query: 771 VPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELS 830
VP P P+++ V +DS T+ W P DGG PILGY +ERK++ W ++ L+
Sbjct: 14886 VPGPPGTPQVTAVTKDSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNI 14945
Query: 831 HEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PIGPPSEPTHLAVEDVSDTTVS 887
++ + +G+ YE RV A N G S+PS S+P + PI PP +P L +++ TV+
Sbjct: 14946 FKSSGLTDGIAYEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPL---NITRHTVT 15002
Query: 888 LKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAH 947
LKW PE G + Y VE W+ A V L A FRV A
Sbjct: 15003 LKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAK 15062
Query: 948 NMAGP-GAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVT 1006
N AG P ++ +T ++ ++ P++++ + T+ K GE L G+P P +
Sbjct: 15063 NAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTME 15122
Query: 1007 WTKEGQPLAG-EEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDK 1065
W+K+G+ L G ++ I+ + T L + + R SG Y +T K ++V+D+
Sbjct: 15123 WSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDR 15182
Query: 1066 PSPPQ-DLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHC 1124
P PP+ L VT+ L W PP D G ++ Y VQK + + W V + T
Sbjct: 15183 PGPPEGPLAVTEVTSEKCVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKL 15242
Query: 1125 VVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPN 1171
V +L+ GN Y FRV + N G + EPV P Y PP+
Sbjct: 15243 KVTKLLKGNEYIFRVMAVNKYGVGE--PLESEPVLAVNP---YGPPD 15284
Score = 199 bits (506), Expect = 1e-50
Identities = 156/565 (27%), Positives = 253/565 (44%), Gaps = 26/565 (4%)
Query: 702 PEDTGDSD--EWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGE 759
P+D G S+ ++ +K+ + V + ++ F V + E + V+ +N G
Sbjct: 13728 PKDDGGSEITNYILEKRDSVNNKW-VTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGV 13786
Query: 760 DQVNLTVKVI-----DVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKK 814
+ + ++ DVPDAP P I +V DS ++ W P GG PI GY LE K++
Sbjct: 13787 GEGLKSEPIVARHPFDVPDAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERN 13846
Query: 815 SYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPT 874
S W R N I+ + + EG+ YE RV A+N G+ +PS S+P + + P P
Sbjct: 13847 SLLWKRANKTPIRMRDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPG 13906
Query: 875 HLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDL 934
V +++ +V+L W P+ G L GY VE W+ A + V DL
Sbjct: 13907 KPEVINITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDL 13966
Query: 935 PTGARLLFRVRAHNMAGP-GAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNL 993
G + FR+RA N AG AP +TE + ++ + P + L ++ + K G+ + L
Sbjct: 13967 VEGGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVL 14026
Query: 994 -LIPFQGKPRPQVTWTKEGQPLAGEEVS-IRNSPTDTILFIRAARRVHSGTYQVTVRIEN 1051
I GKP P+ +W+K G+ + +++ I ++PT ++L I+ A R +G Y +T
Sbjct: 14027 NAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPF 14086
Query: 1052 MEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTME 1111
+ + V+D P PP + +++ L W PP + G + + Y ++K + +
Sbjct: 14087 GTKVEHVKVTVLDVPGPPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLL 14146
Query: 1112 WFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPV-----FIPRPGIT 1166
W V E + V +LI GN Y FRV + N G + EPV F P PG
Sbjct: 14147 WTVVSEDIQSCRHVATKLIQGNEYIFRVSAVNHYGKGE--PVQSEPVKMVDRFGP-PGPP 14203
Query: 1167 YEPPNYKALDFSEAPSFTQPLVN-RSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDA 1225
+P + S+ +P+ + S I GY V K + W + D
Sbjct: 14204 EKPEVSNVTKNTATVSWKRPVDDGGSEITGY------HVERREKKSLRWVRAIKTPVSDL 14257
Query: 1226 RFRMFSKQGVLTLEIRKPCPFDGGI 1250
R ++ Q T E R GI
Sbjct: 14258 RCKVTGLQEGSTYEFRVSAENRAGI 14282
Score = 197 bits (500), Expect = 7e-50
Identities = 147/509 (28%), Positives = 216/509 (42%), Gaps = 42/509 (8%)
Query: 644 PPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPE 703
PP++ LD R D I V G +R+ + G P P + W K
Sbjct: 11533 PPEVELDVTCR--DVITVRVGQTIRILARVKGRPEPDITWTK------------------ 11572
Query: 704 DTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVN 763
+ K+L E RV + R ++ A + D G Y ++ KN G Q +
Sbjct: 11573 ----------EGKVLVR-EKRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSGHAQGS 11621
Query: 764 LTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNF 823
V V+D P K++NV +++CT+ WE P +GG I +I+E +K W +
Sbjct: 11622 AIVNVLDRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIVEYRKPNQKGWSIVAS 11681
Query: 824 DLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGP---PSEPTHLAVED 880
D+ + L ++ Y RV A N +G+ P + I P P EP +L + D
Sbjct: 11682 DVTKRLIKA--NLLANNEYYFRVCAENKVGVGPTIETKTPILAINPIDRPGEPENLHIAD 11739
Query: 881 VSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARL 940
T V LKWR P+ G Y VE +G +W +G + T +V
Sbjct: 11740 KGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVENQIY 11799
Query: 941 LFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGK 1000
FRV+ N G V T E V V+E LQ+P L L L + K G+ + L +GK
Sbjct: 11800 EFRVQTKNEGGESDWVKTEE-VVVKEDLQKPVLDLK--LSGVLTVKAGDTIRLEAGVRGK 11856
Query: 1001 PRPQVTWTKEGQPL---AGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKAT 1057
P P+V WTK+ V I + + A+R G Y VT A
Sbjct: 11857 PFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAY 11916
Query: 1058 LVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLE 1117
+ V+DKP P ++L++ D + W PP+D G E+ Y ++K + K M W T
Sbjct: 11917 ATVNVLDKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSA 11976
Query: 1118 HYRRTHCVVPELIIGNGYYFRVFSQNMVG 1146
V LI GN Y FRV ++N +G
Sbjct: 11977 TVLTPGTTVTRLIEGNEYIFRVRAENKIG 12005
Score = 196 bits (498), Expect = 1e-49
Identities = 146/539 (27%), Positives = 227/539 (42%), Gaps = 73/539 (13%)
Query: 635 KIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAP 694
+I V QE P+I LD ++ + V AG K+ L ++G P P + W KA
Sbjct: 7306 EIQAVDTQEAPEIFLDV--KLLAGLTVKAGTKIELPATVTGKPEPKITWTKA-------- 7355
Query: 695 ARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVK 754
++ + + R+ +E +S T+ +++ D G Y +
Sbjct: 7356 ---------------------DMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAV 7394
Query: 755 NPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKK 814
N G + V V+D P PAA I++V +SC + W PP DGG I Y++ER+
Sbjct: 7395 NVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATD 7454
Query: 815 SYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRP---SPASQPFMPIGPPS 871
S W +L+ +++ + +A ++I Y RV A N G+ P SP + + PP
Sbjct: 7455 SEVWHKLS-STVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITAKYQ-FDPPG 7512
Query: 872 EPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILV 931
PT L D++ V+L W P+ G + GY VE +WV + + T+ V
Sbjct: 7513 PPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRV 7572
Query: 932 KDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPV 991
K L + FRV A N+AGPG P +TEP+ +++ + P P
Sbjct: 7573 KGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPP----------------WPPG 7616
Query: 992 NLLIPFQGKPRPQVTWTKEGQPLAG--EEVSIRNSPTDTILFIRAARRV----------- 1038
+ GK ++ WTK E I T T ++R A V
Sbjct: 7617 KPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVPTTQHLLPGLM 7676
Query: 1039 HSGTYQVTVRIENMEDKA--------TLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQ 1090
Y VR N ++ L + + PSPP+ L V + L+W P+
Sbjct: 7677 EGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPE 7736
Query: 1091 DVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSD 1149
G + + Y V+K D + W TV + T C V L G+ Y FRV ++N +G SD
Sbjct: 7737 KDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSD 7795
Score = 196 bits (498), Expect = 1e-49
Identities = 162/633 (25%), Positives = 260/633 (41%), Gaps = 83/633 (13%)
Query: 642 QEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDA 701
QE P++ +D + D +V AG+++R+ I G P P W+ + KA D
Sbjct: 9433 QEEPEVFIDIGAQ--DCLVCKAGSQIRIPAVIKGRPTPKSSWEFD-GKAKKAMKDGVHDI 9489
Query: 702 PEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQ 761
PED ++ET ++ S+ + ++ G Y++T KN G+
Sbjct: 9490 PEDA--------------------QLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKT 9529
Query: 762 VNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRL 821
N VKV+DVP P K+S++ SC + W+ P DGG I GY++E++ W ++
Sbjct: 9530 ANCRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKRTIDGKAWTKV 9589
Query: 822 NFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PIGPPSEPTHLAV 878
N D + ++ Y RV A N G+ P Q PI PP P L +
Sbjct: 9590 NPDC-GSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKI 9648
Query: 879 EDVSDTTVSLKWRPPERVGAGGLDGYSVE---YCPEGCSE--WVAALQGLTEHTSILVKD 933
++ TV L W+PP+ G + Y VE + P G + W + E V+D
Sbjct: 9649 GLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVED 9708
Query: 934 LPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNL 993
L G FRV+A N AG P T P Q RP + L++ ++ + G VN+
Sbjct: 9709 LVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQ----RPDMPPSIDLKEFMEVEEGTNVNI 9764
Query: 994 LIPFQGKPRPQVTWTK-------EGQPLAGEEVSIRNSPTDTI-LFIRAARRVHSGTYQV 1045
+ +G P P +TW K +P+ + + DT L I +RR +G Y +
Sbjct: 9765 VAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTI 9824
Query: 1046 TVRIENMEDKATLVLQVVDKPSPPQD-LRVTDAWGLNVALEWKPPQDVGNTELWGYTVQK 1104
T + L V+ +P PP ++ + L W PP+D G +++ Y ++K
Sbjct: 9825 TAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIEK 9884
Query: 1105 ADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPV--FIPR 1162
+ W V + +P+L+ G+ Y FR+ +QN G + + E
Sbjct: 9885 REANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFSV 9944
Query: 1163 PG----------------ITYEPPNYKA--------LDFSEAPSFTQPLVNRSVIAGYTA 1198
PG + +E P Y L+ + S VNR I T
Sbjct: 9945 PGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMTL 10004
Query: 1199 MLCCAVRGSPKPKISWFKNGLDLGEDARFRMFS 1231
+S+ GL G D +FR+++
Sbjct: 10005 ------------GVSYKVTGLIEGSDYQFRVYA 10025
Score = 195 bits (495), Expect = 3e-49
Identities = 127/403 (31%), Positives = 185/403 (45%), Gaps = 20/403 (4%)
Query: 772 PDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSH 831
P P+ P++S + +DS V W P DGG I GYILE++ K+ RW + N + +L
Sbjct: 18530 PGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLTDLRL 18589
Query: 832 EARRMIEGVVYEMRVYAVNAIGMSRPSP------ASQPFMPIGPPSEPTHLAVEDVSDTT 885
+ EG YE RV A NA G+ PS A P GPPS P V D S ++
Sbjct: 18590 RVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNP---KVTDTSRSS 18646
Query: 886 VSLKWRPPERVGAGGLDGYSVEYCPEGCSEWV-----AALQGLTEHTSILVKDLPTGARL 940
VSL W P G + GY VE EW LQG V L
Sbjct: 18647 VSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQG----KQFTVTKLKENTEY 18702
Query: 941 LFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGK 1000
FR+ A N G G P T V QE ++ P ++L LR+ + + + L + +G+
Sbjct: 18703 NFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRASATLRLFVTIKGR 18762
Query: 1001 PRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVL 1060
P P+V W K + + + I + + T+L I R SG Y +T+ + A + +
Sbjct: 18763 PEPEVKWEK-AEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSGSKTAFVNV 18821
Query: 1061 QVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYR 1120
+V+D PS P +L + + +V L W+PP G ++ Y V+K + + T+ +
Sbjct: 18822 RVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATITNNCT 18881
Query: 1121 RTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRP 1163
+T + L G YYFRV + N G A TT EPV + P
Sbjct: 18882 KTTFRIENLQEGCSYYFRVLASNEYGIGLPAETT-EPVKVSEP 18923
Score = 191 bits (485), Expect = 4e-48
Identities = 129/467 (27%), Positives = 213/467 (45%), Gaps = 18/467 (3%)
Query: 772 PDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSH 831
P P P + + +DS +QW P +GG P++GY LERK++ S W ++N +I +
Sbjct: 17051 PGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQF 17110
Query: 832 EARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PIGPPSEPTHLAVEDVSDTTVSL 888
+A+ + EG+ YE RVYA N +G+ + S S+ ++ P PP P + V+ ++L
Sbjct: 17111 KAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPPGTPEPIMVK---RNEITL 17167
Query: 889 KWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHN 948
+W P G + GY VE W+ A T V L R FRV A N
Sbjct: 17168 QWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKN 17227
Query: 949 MAGP-GAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTW 1007
AG P +T P+T ++ ++ PR+ + R TI GE L GKP P + W
Sbjct: 17228 AAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEW 17287
Query: 1008 TKEGQPL-AGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKAT--LVLQVVD 1064
+ + + I+N+ +L ++ A R+ G Y +R N+ + + ++V+D
Sbjct: 17288 LRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQY--ILRASNVAGSKSFPVNVKVLD 17345
Query: 1065 KPSPPQ-DLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTH 1123
+P PP+ ++VT +L W PP G +++ Y V+K + + W V
Sbjct: 17346 RPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNS 17405
Query: 1124 CVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSF 1183
V +L+ GN Y FR+ + N G + + PV + P + PP K+L+ +
Sbjct: 17406 LKVTKLLEGNEYVFRIMAVNKYGVGEPLESA--PVLMKNPFVLPGPP--KSLEVTNIAKD 17461
Query: 1184 TQPLV-NRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRM 1229
+ + NR G + ++ V + I W K D R R+
Sbjct: 17462 SMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRV 17508
Score = 189 bits (480), Expect = 1e-47
Identities = 125/408 (30%), Positives = 194/408 (47%), Gaps = 15/408 (3%)
Query: 771 VPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELS 830
VP P P ++ DS VQW P DGG ++GY LERK++ S W++LN I +
Sbjct: 15968 VPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTK 16027
Query: 831 HEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PIGPPSEPTHLAVEDVSDTTVS 887
+ + EGV YE RV A N +G+ +PS S+ ++ P PP P + V+ +V+
Sbjct: 16028 FKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAII---VTRNSVT 16084
Query: 888 LKWRPPERVGAGGLDGYSVE--YCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVR 945
L+W+ P G + GY VE PEG W+ A T V L R FRV
Sbjct: 16085 LQWKKPTYDGGSKITGYIVEKKELPEG--RWMKASFTNIIDTHFEVTGLVEDHRYEFRVI 16142
Query: 946 AHNMAGP-GAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQ 1004
A N AG P +T +T ++ + PR+ + + TI GE + GKP P
Sbjct: 16143 ARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPT 16202
Query: 1005 VTWTKEGQPLAG-EEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVV 1063
+ W K Q L+ + I+++ T L ++ A RV SG Y + + E T+ ++V+
Sbjct: 16203 IQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVL 16262
Query: 1064 DKPSPPQ-DLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRT 1122
D+P PP+ + ++ L WKPP G +++ Y V++ + + W V + +
Sbjct: 16263 DRPGPPEGPVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTL 16322
Query: 1123 HCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPP 1170
C V +L+ GN Y FR+ + N G + EPV P + + P
Sbjct: 16323 SCKVTKLLEGNEYTFRIMAVNKYGVGE--PLESEPVVAKNPFVVPDAP 16368
Score = 189 bits (479), Expect = 2e-47
Identities = 129/478 (26%), Positives = 224/478 (46%), Gaps = 24/478 (5%)
Query: 743 KEDEGVYTVTVKNPVG-----EDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAY 797
K +E ++ V N G E + + +P P P+ G++ +QW P
Sbjct: 22834 KNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPES 22893
Query: 798 DGGQPILGYILERKKKKSYRWMRLNFD-LIQELSHEARRMIEGVVYEMRVYAVNAIGMSR 856
DGG I Y++++++KKS RW R+N D ++ + + ++EG Y+ RV AVNA G S
Sbjct: 22894 DGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSE 22953
Query: 857 PSPAS------QPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCP 910
PS AS +P GPPS P V D + ++SL W P G + GY +E
Sbjct: 22954 PSEASNFISCREPSYTPGPPSAPR---VVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQE 23010
Query: 911 EGCSEWVAALQGLT-EHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQ 969
+ +W T +T V DL G + FRV A N+ G + + E ++
Sbjct: 23011 KDTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIE 23070
Query: 970 RPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTI 1029
P L+L L++T+ + G + L++ G+P P +TW+K+G LA + I + + ++
Sbjct: 23071 IPDLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAI-IDTTESYSL 23129
Query: 1030 LFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPP 1089
L + R +G Y + ++ + AT++++V D P P ++V + +V + W+ P
Sbjct: 23130 LIVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIP 23189
Query: 1090 QDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSD 1149
G + Y V+K + + TV +T + L+ G YYFRV +N+ G +
Sbjct: 23190 TIDGGAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGE 23249
Query: 1150 RAATTKEPVFIPRPGITYEPPNYKALDFSEAP---SFTQPLVN-RSVIAGYTAMLCCA 1203
T+ + P + P + +D +++ ++ +PL + S + GY C A
Sbjct: 23250 PCETSDAVLVSEVPLV---PAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKA 23304
Score = 188 bits (477), Expect = 3e-47
Identities = 139/490 (28%), Positives = 224/490 (45%), Gaps = 24/490 (4%)
Query: 700 DAPEDTGDSDEWVF--DKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPV 757
D PED G + + +K+ +T ++ V ++ R+ F V K+ E + V +N
Sbjct: 21307 DVPEDNGGGEITCYSIEKRETSQTNWKM-VCSSVARTTFKVPNLVKDAEYQFRVRAENRY 21365
Query: 758 GEDQVNLTVKVID-----VPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKK 812
G Q ++ ++ +P P P I NV D ++ W+ P YDGG + G+ +E+K+
Sbjct: 21366 GVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKE 21425
Query: 813 KKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQ---PFMPIGP 869
+ S W ++N I + A ++EG+ Y+ RVYA N+ G+S PS S+ P+ P
Sbjct: 21426 RNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDP 21485
Query: 870 PSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSI 929
P P ++ DV+ T++LKW PP R G + GYS+E +G WV
Sbjct: 21486 PGTPDYI---DVTRETITLKWNPPLRDGGSKIVGYSIEK-RQGNERWVRCNFTDVSECQY 21541
Query: 930 LVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTV-QEILQRPRLQLPRHLRQTIQKKVG 988
V L G R FR+ A N G +P + + + + ++ P ++ + K G
Sbjct: 21542 TVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSG 21601
Query: 989 EPVNLLIPFQGKPRPQVTWTKEGQPLAGE-EVSIRNSPTDTILFIRAARRVHSGTYQVTV 1047
E + + QG+P P+VTW K+G + + I + T LF+R A R H G Y V
Sbjct: 21602 ESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEA 21661
Query: 1048 RIENMEDKATLVLQVVDKPSP-PQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKAD 1106
+ + KA + ++V D P +R T+ G + L W P + G + Y ++K +
Sbjct: 21662 KNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRE 21721
Query: 1107 KKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGF-----SDRAATTKEPVFIP 1161
+ W + + +LI GN Y FRV + N G SD +
Sbjct: 21722 TSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPD 21781
Query: 1162 RPGITYEPPN 1171
PGI EP N
Sbjct: 21782 APGIP-EPSN 21790
Score = 185 bits (469), Expect = 3e-46
Identities = 224/932 (24%), Positives = 347/932 (37%), Gaps = 158/932 (16%)
Query: 374 QVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAA 433
+V + ++ E+ A+ KW +N + I SKYI TL I L D A
Sbjct: 6278 RVKEQQEVVFNCEVNTEGAKAKWFRNEEAI-FDSSKYIILQKDLVYTLRIRDAHLDDQAN 6336
Query: 434 YQCVVGGE-----KCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLK 488
Y + K + L V+E + I PL+D M + V F C+V+ +KW K
Sbjct: 6337 YNVSLTNHRGENVKSAANLIVEEEDLRIVEPLKDIETMEKKSVTFWCKVNRLNVTLKWTK 6396
Query: 489 DGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVY 548
+G E+ + YR K +H L I + D G Y + +++AEL++ E E
Sbjct: 6397 NGEEVPFDNRVSYRVDK--YKHMLTIKDCGFPDEGEYIVTAGQDKSVAELLIIEAPTEFV 6454
Query: 549 QSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTP 608
+ + D V D AVF C++S E W +NG+E+ + K G +H+L I D
Sbjct: 6455 EHLEDQTVTEFDDAVFSCQLSREKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDCRL 6514
Query: 609 ADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLR 668
DE +Y+ E A+L E+ ++ + PP+ L+ PG D + + NK +
Sbjct: 6515 DDECEYACGVEDRKSR--ARLFVEEIPVEII---RPPQDILEAPGA--DVVFLAELNKDK 6567
Query: 669 LDVPISGDPAPTVIWQK---AITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRV 725
++V W + + QG+K E + +C+ + R
Sbjct: 6568 VEVQ----------WLRNNMVVVQGDKHQMM------------SEGKIHRLQICDIKPR- 6604
Query: 726 RVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGE 785
D+G Y K+ ++ L AAPKI +
Sbjct: 6605 -------------------DQGEYRFIAKDKEARAKLELA----------AAPKIKTADQ 6635
Query: 786 DSCTVQWEPPAYDGGQPILGYI-LERKKKKSYRWMRLNFDLIQEL-----SHEARRMIEG 839
D D G+P+ + + K W + N L + + R++E
Sbjct: 6636 DLVV--------DVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKTIDTTAEQTSFRILEA 6687
Query: 840 VVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAG 899
+ Y + + I P +L V + D VSL W P G
Sbjct: 6688 KKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDGEVSLAWEEPLTDGGS 6747
Query: 900 GLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGA-RLLFRVRAHNMAGPGAPVTT 958
+ GY VE WV A E V L G LFRV A N G G PV T
Sbjct: 6748 KIIGYVVERRDIKRKTWVLATDR-AESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVET 6806
Query: 959 TEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKE----GQPL 1014
PV R + +P G P+N+ I + +TW G +
Sbjct: 6807 DNPVEA-----RSKYDVP-----------GPPLNVTITDVNRFGVSLTWEPPEYDGGAEI 6850
Query: 1015 AGEEVSIRNSPT---DTILFIRAARR-------VHSGTYQVTVRIENM-----EDKATLV 1059
+ +R+ + DT + +RA V Y VR +N AT
Sbjct: 6851 TNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPF 6910
Query: 1060 LQVVD---KPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVL 1116
++V D +PSPP +L +D +V L+W+PP G + + GY +++ ++ W
Sbjct: 6911 VKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWI--- 6967
Query: 1117 EHYRRTHCVVPELII-------GNGYYFRVFSQNMVGFSDRAAT----TKEPVFIPRPGI 1165
R +VPEL GN Y +RV ++N G SD + T + F+
Sbjct: 6968 ---RCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFV----- 7019
Query: 1166 TYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDA 1225
EP +D S +F L VI + G P+P +W L
Sbjct: 7020 --EP----TMDLS---AFKDGL---EVIVPNPITILVPSTGYPRPTATWCFGDKVLETGD 7067
Query: 1226 RFRMFSKQGVLTLEIRKPCPFDGGIYVCRATN 1257
R +M + L I D GIY + N
Sbjct: 7068 RVKMKTLSAYAELVISPSERSDKGIYTLKLEN 7099
Score = 184 bits (467), Expect = 5e-46
Identities = 128/483 (26%), Positives = 224/483 (46%), Gaps = 20/483 (4%)
Query: 702 PEDTGDSD--EWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVG- 758
PE G S ++ +K+ + +G V+TT + TV + V+ V +N +G
Sbjct: 7735 PEKDGGSPITNYIVEKRDV-RRKGWQTVDTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQ 7793
Query: 759 ------EDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKK 812
ED V L P P A + +V + ++WEPP DGG+PI Y++E+K+
Sbjct: 7794 SDYTEIEDSV-LAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKE 7852
Query: 813 KKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PIGP 869
+ RW++ + + +IEG + +V A N G+ PS ++ P P
Sbjct: 7853 RLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSP 7912
Query: 870 PSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSI 929
PS P L V D +++ W+PPE+ G + GY VE CP G +W+ +
Sbjct: 7913 PSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKF 7972
Query: 930 LVKD-LPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVG 988
V++ + + RVRA N G P +E V ++ +P + L H I+ G
Sbjct: 7973 KVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHDIIVIE---G 8029
Query: 989 EPVNLLIPFQGKPRPQVTWTKEGQPL-AGEEVSIRNSPTDTILFIRAARRVHSGTYQVTV 1047
E +++ +PF+ P P V+W K+G+ + A + ++++N L + + R +G Y +T+
Sbjct: 8030 EKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITL 8089
Query: 1048 RIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADK 1107
+ A++ ++V+ P P +D++ +D + L W+PP+ G T + Y +++ +
Sbjct: 8090 ENKLGSATASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREA 8149
Query: 1108 KTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITY 1167
+ V+ + V +LI Y+FRV + N VG K PV P
Sbjct: 8150 GRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVG-GGEYIELKNPVIAQDPKQPP 8208
Query: 1168 EPP 1170
+PP
Sbjct: 8209 DPP 8211
Score = 183 bits (465), Expect = 8e-46
Identities = 119/406 (29%), Positives = 184/406 (45%), Gaps = 15/406 (3%)
Query: 772 PDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSH 831
P P P ++++ +D VQW P DGG I+GY LE+K+K S W++LN IQ+
Sbjct: 18133 PGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKF 18192
Query: 832 EARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PIGPPSEPTHLAVEDVSDTTVSL 888
+ + EG+ YE +V A N +G+ +PS S+ F+ P PP P + ++ V+L
Sbjct: 18193 KTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAIV---ITRNNVTL 18249
Query: 889 KWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHN 948
KW+ P G + GY VE W+ A T V L R FRV A N
Sbjct: 18250 KWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGLVEDQRYEFRVIARN 18309
Query: 949 MAGP-GAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTW 1007
AG P ++ +T ++ + P L + I GE L +GKP P V W
Sbjct: 18310 AAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVW 18369
Query: 1008 TKEGQPL--AGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDK 1065
+K+G+ L + I+++ T L ++ R G Y + + + ++V+D+
Sbjct: 18370 SKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDR 18429
Query: 1066 PSPPQ-DLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHC 1124
P PP+ L+VT L W PP G + Y ++K + + W V + +
Sbjct: 18430 PGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLSWTQVSTEVQALNY 18489
Query: 1125 VVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPP 1170
V +L+ GN Y FRV + N G + PV P Y+PP
Sbjct: 18490 KVTKLLPGNEYIFRVMAVNKYGIGE--PLESGPVTACNP---YKPP 18530
Score = 183 bits (465), Expect = 8e-46
Identities = 149/599 (24%), Positives = 245/599 (40%), Gaps = 43/599 (7%)
Query: 577 WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKI 636
W K+G+ L +R+ VS V L+I + + D Y A +++ + + I
Sbjct: 19056 WRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSIT-----VPITI 19110
Query: 637 DFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPAR 696
+ R PP +R+D +S D T+ W G +
Sbjct: 19111 IVLDRPGPP-------------------GPIRID-EVSCDSI-TISWNPPEYDGGCQISN 19149
Query: 697 PAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNP 756
+ E T S W + + T ++ TT F V + + Y+
Sbjct: 19150 YIVEKKETT--STTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYS------ 19201
Query: 757 VGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSY 816
E + P P PK+ + + + V W+ P DGG ++GY LE K++ S
Sbjct: 19202 --ESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSI 19259
Query: 817 RWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHL 876
W + N LI + + + EG++YE RVYA N G+ + S + +P P P
Sbjct: 19260 LWSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQP 19319
Query: 877 AVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPT 936
V +++ +VSLKW P G + GY VE W+ + T V +L
Sbjct: 19320 EVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQETYFEVTELTE 19379
Query: 937 GARLLFRVRAHNMA-GPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLI 995
R FRV A N A P +T P+ V++ ++ PR+ + R I K GE + +
Sbjct: 19380 DQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINA 19439
Query: 996 PFQGKPRPQVTWTKEGQPLAGE-EVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMED 1054
G+P P ++W K+G + I ++ T+L ++ R +G Y +T++
Sbjct: 19440 DIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTR 19499
Query: 1055 KATLVLQVVDKPSPPQ-DLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWF 1113
+ +V+DKP PP L + +L W PQ+ G ++ Y V+K + + W
Sbjct: 19500 SVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQEDGGADIDYYIVEKRETSHLAWT 19559
Query: 1114 TVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDR----AATTKEPVFIPRPGITYE 1168
+ T C V +L+ GN Y FRV N G + A +P +P P + E
Sbjct: 19560 ICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLE 19618
Score = 182 bits (462), Expect = 2e-45
Identities = 114/380 (30%), Positives = 178/380 (46%), Gaps = 5/380 (1%)
Query: 771 VPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELS 830
+P P + +++N+ +DS TV W P DGG I+GYI+E++ + RW++ N I +L
Sbjct: 17446 LPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLR 17505
Query: 831 HEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PIGPPSEPTHLAVEDVSDTTVS 887
+ E YE RV A NA G+ PSPA+ + P+ P PT+ + D + +++
Sbjct: 17506 LRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHIVDTTKNSIT 17565
Query: 888 LKWRPPERVGAGGLDGYSVEYCPEGCSEW-VAALQGLTEHTSILVKDLPTGARLLFRVRA 946
L W P G + GY VE C EW + Q T + L RV A
Sbjct: 17566 LAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCA 17625
Query: 947 HNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVT 1006
N G G + V ++ L+ P L L LR+ I + G + IPF+G+P P++T
Sbjct: 17626 LNKVGLGEATSVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGSARIHIPFKGRPTPEIT 17685
Query: 1007 WTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKP 1066
W++E ++V I T L I R +G Y + + + A + ++V+D P
Sbjct: 17686 WSREEGEFT-DKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTP 17744
Query: 1067 SPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVV 1126
PPQ+L V + + L W+PP G ++ Y + K + + V +T V
Sbjct: 17745 GPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKV 17804
Query: 1127 PELIIGNGYYFRVFSQNMVG 1146
L G YYFRV ++N G
Sbjct: 17805 ENLTEGAIYYFRVMAENEFG 17824
Score = 180 bits (456), Expect = 9e-45
Identities = 116/381 (30%), Positives = 183/381 (48%), Gaps = 6/381 (1%)
Query: 772 PDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSH 831
P AP P++ +V ++ +++WE P +DGG I+GY +E+K++ + W++ N E ++
Sbjct: 22469 PSAPTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNY 22528
Query: 832 EARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWR 891
+ ++EG+ Y+ R YA+NA G+S+ S AS+P M P P V DV+ +TVSL W
Sbjct: 22529 KVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQNPVDAPGRPEVTDVTRSTVSLIWS 22588
Query: 892 PPERVGAGGLDGYSVEYCP---EGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHN 948
P G + GY +E P G W+ + V L G FRV A N
Sbjct: 22589 APAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKN 22648
Query: 949 MAGP-GAPVTTTEPVTVQEILQRPRLQLPRHLR-QTIQKKVGEPVNLLIPFQGKPRPQVT 1006
AG +T PVT ++ P+ +L L + + G + L GKP P++
Sbjct: 22649 AAGVISKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIRAGSDLVLDAAVGGKPEPKII 22708
Query: 1007 WTKEGQPL-AGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDK 1065
WTK + L E+VS++ + I+ R SG Y +TV+ + +++++V+D
Sbjct: 22709 WTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLDS 22768
Query: 1066 PSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCV 1125
P P L V+ L W PQ+ G E+ Y V++ + + W V V
Sbjct: 22769 PGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLSYV 22828
Query: 1126 VPELIIGNGYYFRVFSQNMVG 1146
V LI N Y FRV + N G
Sbjct: 22829 VTRLIKNNEYIFRVRAVNKYG 22849
Score = 171 bits (432), Expect = 5e-42
Identities = 157/594 (26%), Positives = 238/594 (40%), Gaps = 72/594 (12%)
Query: 707 DSDEWVFDKKL-LCETEGRVRVETTKDRSIFTV-----EGAEKEDEGVYTVTVKNPVGED 760
D+D+WV K+ + +T RV+ T K + F V G K + + +K+P
Sbjct: 7553 DTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDP---- 7608
Query: 761 QVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMR 820
ID P P P + +VG+ S + W P +DGG I Y++E K + W+R
Sbjct: 7609 --------IDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVR 7660
Query: 821 LNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PIGPPSEPTHLA 877
+ + + H ++EG Y RV AVN G S PS S P + + PPS P L
Sbjct: 7661 VA-EGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLE 7719
Query: 878 VEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTG 937
V +++ T LKW PE+ G + Y VE W + + T V L G
Sbjct: 7720 VINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGW-QTVDTTVKDTKCTVTPLTEG 7778
Query: 938 ARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKV---------- 987
+ +FRV A N G + V ++ P + ++ V
Sbjct: 7779 SLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKND 7838
Query: 988 -GEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSP----TDTILFIRAARRVHSGT 1042
G P+ + + K R W K G+ AG + + R + T+ +RA G
Sbjct: 7839 GGRPIQRYV-IEKKERLGTRWVKAGKT-AGPDCNFRVTDVIEGTEVQFQVRAENEAGVGH 7896
Query: 1043 YQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTV 1102
I ++ED + PSPP DL VTDA ++A+ WKPP+ G + + GY V
Sbjct: 7897 PSEPTEILSIEDPTS-------PPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHV 7949
Query: 1103 QKADKKTMEWFTVLEH------YRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKE 1156
+ T +W V ++ VVP+ Y RV + N +G S E
Sbjct: 7950 EMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPD----KEYVLRVRAVNAIGVS-------E 7998
Query: 1157 PVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFK 1216
P I + +P +D T ++ VI G + R P P +SW K
Sbjct: 7999 PSEISENVVAKDPDCKPTIDLE-----THDII---VIEGEKLSIPVPFRAVPVPTVSWHK 8050
Query: 1217 NGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
+G ++ R M + LE+ K D GIY N G A ++V
Sbjct: 8051 DGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKV 8104
Score = 151 bits (381), Expect = 4e-36
Identities = 127/445 (28%), Positives = 198/445 (44%), Gaps = 36/445 (8%)
Query: 750 TVTVKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILE 809
T + +P+ V + + P AP P I+ V +DSC V W+PPA DGG I Y LE
Sbjct: 24431 TFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLE 24490
Query: 810 RKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPF----- 864
+++KK +W+ + + I+E + +IEG+ YE RV N G S S S+P
Sbjct: 24491 KREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSD 24550
Query: 865 MPIGPP---SEPTHLAVEDVSDTTVSLK-WRPPERVGAGGLDGYSVEYCPEGCSEWVAAL 920
+PI P E +L V S+ T+ K P+ + G E +G +
Sbjct: 24551 VPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQG--KEIIADGLKYRIQEF 24608
Query: 921 QGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLR 980
+G + +++ + +++VRA N G + E+ ++ LP+ L
Sbjct: 24609 KG--GYHQLIIASVTDDDATVYQVRATNQGG------SVSGTASLEVEVPAKIHLPKTLE 24660
Query: 981 --QTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGE----EVSIRNSPTDTILFIRA 1034
+ GE V++ IPF GKP P +TW K GQ L +V + S T +++F
Sbjct: 24661 GMGAVHALRGEVVSIKIPFSGKPDPVITWQK-GQDLIDNNGHYQVIVTRSFT-SLVFPNG 24718
Query: 1035 ARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGN 1094
R +G Y V + D+ T+ L V D P PP+ ++V+D +V L W P G
Sbjct: 24719 VERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGG 24778
Query: 1095 TELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATT 1154
+++ Y V+K W V R T V L Y FRV ++N G S
Sbjct: 24779 SKITNYIVEKCATTAERWLRV-GQARETRYTVINLFGKTSYQFRVIAENKFGLS------ 24831
Query: 1155 KEPVFIPRPGITYEPPNYKALDFSE 1179
+P P IT E +A+++ E
Sbjct: 24832 -KPSEPSEPTITKEDKT-RAMNYDE 24854
Score = 144 bits (364), Expect = 4e-34
Identities = 106/366 (28%), Positives = 162/366 (44%), Gaps = 48/366 (13%)
Query: 640 PRQEPPKI--------HLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGN 691
PR+ P I LD G ++ AG+ +++++P+ G P PTV W+K
Sbjct: 14676 PRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKK------ 14729
Query: 692 KAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTV 751
GD ++L +T+ RV ETT +I + + D G Y +
Sbjct: 14730 --------------GD--------QILKQTQ-RVNFETTATSTILNINECVRSDSGPYPL 14766
Query: 752 TVKNPVGEDQVNLTVKVIDVPDAPAAP-KISNVGEDSCTVQWEPPAYDGGQPILGYILER 810
T +N VGE +T++V D+P P P K V D T W+PP DGG PI Y++E
Sbjct: 14767 TARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEM 14826
Query: 811 KKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGM-----SRPSPASQPFM 865
++ S W+ L +I+ +++A R+ G+ Y+ RV A N G+ S A+ PF
Sbjct: 14827 RQTDSTTWVELATTVIRT-TYKATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFK 14885
Query: 866 PIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTE 925
GPP P V V+ ++++ W P G + GY VE W + L
Sbjct: 14886 VPGPPGTPQ---VTAVTKDSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVP 14942
Query: 926 HTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHL-RQTIQ 984
L G FRV A NMAG P +EP+ + + P +P ++ R T+
Sbjct: 14943 GNIFKSSGLTDGIAYEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHTVT 15002
Query: 985 KKVGEP 990
K +P
Sbjct: 15003 LKWAKP 15008
Score = 142 bits (357), Expect = 3e-33
Identities = 105/345 (30%), Positives = 153/345 (44%), Gaps = 43/345 (12%)
Query: 635 KIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNK-LRLDVPISGDPAPTVIWQKAITQGNKA 693
+I V R + LD G +PD + N RL +PI G PAP+V W+K
Sbjct: 13596 EITVVARDDVVAPDLDLKG-LPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKG------- 13647
Query: 694 PARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTV 753
ED T+ RV VE++ + V +K D G YT+T+
Sbjct: 13648 ---------EDP-------------LATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITL 13685
Query: 754 KNPVGEDQVNLTVKVIDVPDAPAAP-KISNVGEDSCTVQWEPPAYDGGQPILGYILERKK 812
KN G + +++KV+ P P P K V ++ T++W PP DGG I YILE++
Sbjct: 13686 KNVAGTKEGTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRD 13745
Query: 813 KKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGM-----SRPSPASQPF-MP 866
+ +W+ +Q+ + R+ EG+ Y RV A N G+ S P A PF +P
Sbjct: 13746 SVNNKWVTC-ASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVP 13804
Query: 867 IGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEH 926
PP P ++ DV +VSL W P++ G + GY +E+ W A +
Sbjct: 13805 DAPP--PPNIV--DVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRM 13860
Query: 927 TSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRP 971
V L G FRV A N+AG G P +EPV + + P
Sbjct: 13861 RDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPP 13905
Score = 140 bits (352), Expect = 1e-32
Identities = 120/428 (28%), Positives = 177/428 (41%), Gaps = 58/428 (13%)
Query: 375 VSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAY 434
V+ G EL+ D V+W G++++ S K + S G TLT+ L D
Sbjct: 5835 VTAGETATFDCELSYEDIPVEWYLKGKKLEPS-DKVVPRSEGKVHTLTLRDVKLEDAGEV 5893
Query: 435 QCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELT 494
Q K LFVKEPPV T+PLEDQ V G ECEVS E A+VKW K+G E+
Sbjct: 5894 QLTAKDFKTHANLFVKEPPVEFTKPLEDQTVEEGATAVLECEVSRENAKVKWFKNGTEIL 5953
Query: 495 REETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADL 554
+ + KY DG+ L+I++ ED Y + L V +E + + DL
Sbjct: 5954 KSK--KYEIVADGRVRKLVIHDCTPEDIKTYTCDAKDFKTSCNLNVVPPHVEFLRPLTDL 6011
Query: 555 MVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADY 614
V K+ A F+CE+S EN + W K+G E+ + + G V L I+ DEA+Y
Sbjct: 6012 QVREKEMARFECELSRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEY 6071
Query: 615 SFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPIS 674
S E S L +E + F I V + ++L +S
Sbjct: 6072 SC--EVRTARTSGMLTVLEEEAVFTKNLA--------------NIEVSETDTIKLVCEVS 6115
Query: 675 GDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRS 734
P VIW K GD + + ET GR + T +
Sbjct: 6116 -KPGAEVIWYK--------------------GDEE--------IIET-GRYEILTEGRKR 6145
Query: 735 IFTVEGAEKEDEGVYTVTVKNPVGEDQV---NLTVKVIDVP------DAPAAPKISNVGE 785
I ++ A ED G Y + + + +V L + I P + A + ++ +
Sbjct: 6146 ILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLEILEGEKAEFVCSISK 6205
Query: 786 DSCTVQWE 793
+S VQW+
Sbjct: 6206 ESFPVQWK 6213
Score = 137 bits (345), Expect = 7e-32
Identities = 127/511 (24%), Positives = 201/511 (39%), Gaps = 87/511 (17%)
Query: 643 EPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAP 702
+ P LD + D IVV AG L+ I G P P V+W K
Sbjct: 18331 DAPNASLD--PKYKDVIVVHAGETFVLEADIRGKPIPDVVWSK----------------- 18371
Query: 703 EDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQV 762
D K L ET R+ +++T ++ V+ + D G Y + + N G +
Sbjct: 18372 -----------DGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSI 18420
Query: 763 NLTVKVIDVPDAPAAP-KISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRL 821
+TVKV+D P P P K++ V + C + W PP DGG I YI+E+++ W ++
Sbjct: 18421 PITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLSWTQV 18480
Query: 822 NFDLIQELSHEARRMIEGVVYEMRVYAVNAIGM-----SRPSPASQPFMPIGPPSEPTHL 876
+ + +Q L+++ +++ G Y RV AVN G+ S P A P+ P GPPS P
Sbjct: 18481 STE-VQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACNPYKPPGPPSTP--- 18536
Query: 877 AVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPT 936
V ++ ++ + W P G ++GY +E + W + + V L
Sbjct: 18537 EVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLTDLRLRVTGLTE 18596
Query: 937 GARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIP 996
G FRV A N AG G P + + L P G P N +
Sbjct: 18597 GHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPP----------------GPPSNPKVT 18640
Query: 997 FQGKPRPQVTWTKE----GQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENM 1052
+ + W+K G P+ G V ++ + D + + VT EN
Sbjct: 18641 DTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENT 18700
Query: 1053 E--------------DKATLVLQVV--DKPSPPQ-----------DLRVTDAWGLNVALE 1085
E + ATL VV ++ PP+ LR + L V ++
Sbjct: 18701 EYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRASATLRLFVTIK 18760
Query: 1086 WKPPQDVGNTELWGYTVQKADKKTMEWFTVL 1116
+P +V + G +A + FT+L
Sbjct: 18761 GRPEPEVKWEKAEGILTDRAQIEVTSSFTML 18791
Score = 135 bits (340), Expect = 2e-31
Identities = 215/933 (23%), Positives = 349/933 (37%), Gaps = 118/933 (12%)
Query: 378 GHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCV 437
G + EL EV+WL+N + + G K+ S G L I D Y+ +
Sbjct: 6554 GADVVFLAELNKDKVEVQWLRNNMVV-VQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFI 6612
Query: 438 VGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSE-EGAQVKWLKDGVELTRE 496
++ +L + P + T +D +V VG+ + A+ +W K+ L+ +
Sbjct: 6613 AKDKEARAKLELAAAPKIKTAD-QDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTK 6671
Query: 497 ETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMV 556
++ I EA D G Y + AE + K ++V + +L V
Sbjct: 6672 T-----IDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEV 6726
Query: 557 GAKDQAVFKCEVSDENVRGVW---LKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEAD 613
E D V W L +G + ++ I R + D + E
Sbjct: 6727 ---------TETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAESCEFT 6777
Query: 614 YSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPI 673
+ + +G + F + V EP + D P V A +K DVP
Sbjct: 6778 VTGLQKG-----GVEYLFRVSARNRVGTGEP--VETDNP--------VEARSKY--DVP- 6819
Query: 674 SGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSD--EWVFDKK----LLCETEGRVRV 727
G P I T N+ + PE G ++ +V + + + +T VR
Sbjct: 6820 -GPPLNVTI-----TDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRA 6873
Query: 728 ETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLT---VKVIDVPDAPAAP---KIS 781
E VEG E + V +N +G + + VKV D + P+ P S
Sbjct: 6874 EDLSATVTDVVEGQEYS----FRVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSS 6929
Query: 782 NVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVV 841
+ + S ++WEPP DGG PILGYI+ER ++ W+R N L+ EL+++ + +G
Sbjct: 6930 DQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNK 6989
Query: 842 YEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGA-GG 900
Y RV A N G+S PS P EPT D+S L+ P +
Sbjct: 6990 YLYRVSAENKAGVSDPSEILGPLTADDAFVEPTM----DLSAFKDGLEVIVPNPITILVP 7045
Query: 901 LDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTE 960
GY P + W + L + +K L A L+ + G
Sbjct: 7046 STGY-----PRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENR 7100
Query: 961 PVTVQ-----EILQRPRLQLPRHLR-------------QTIQKKVGEPVNLLIPFQGKPR 1002
T+ ++ RP P+ L+ + G P+ + + +
Sbjct: 7101 VKTISGEIDVNVIARP--SAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYV-VEKREV 7157
Query: 1003 PQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIE--NMEDKATLVL 1060
+ TWTK + E ++ + + R G + E NM AT+
Sbjct: 7158 SRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATV-- 7215
Query: 1061 QVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYR 1120
P PP++++ D ++ L W PP++ G + + GY V++ + + +W E
Sbjct: 7216 -----PDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGEPVA 7270
Query: 1121 RTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEA 1180
T V L G Y +RV + N G S + T+E +A+D EA
Sbjct: 7271 ETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEE---------------IQAVDTQEA 7315
Query: 1181 PSF---TQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLT 1237
P + L +V AG L V G P+PKI+W K + L +D R + + T
Sbjct: 7316 PEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKST 7375
Query: 1238 LEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
+ I D G Y+ A N+ G A + V
Sbjct: 7376 VTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNV 7408
Score = 134 bits (338), Expect = 4e-31
Identities = 121/458 (26%), Positives = 200/458 (43%), Gaps = 38/458 (8%)
Query: 708 SDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVK 767
+D+WV K ++ TT ++TV G + E + + +N VG + + +
Sbjct: 24001 TDKWVRHNK--------TQITTT----MYTVTGLVPDAEYQFRIIAQNDVGLSETSPASE 24048
Query: 768 VI------DVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRL 821
+ D P P +I ++ +DS T+QWE P DGG+ ILGY +E ++ W +
Sbjct: 24049 PVVCKDPFDKPSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKS 24108
Query: 822 NFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDV 881
N + I++ ++E YE RV+A N G+SRP + E + E +
Sbjct: 24109 NKERIKDKQFTIGGLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPGIRKE-M 24167
Query: 882 SDTTVSLKWRPPERVGAGGLDGYSVEYCPEG-----CSEWVAALQGLTEHTSILVKDLPT 936
D T L G +++ G ++ + G T +++ ++
Sbjct: 24168 KDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQED 24227
Query: 937 GARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIP 996
++ A N G V T+ + +Q P+ L++ VG + L +
Sbjct: 24228 EG--VYTCIATNEVGE---VETSSKLLLQAT---PQFHPGYPLKEKYYGAVGSTLRLHVM 24279
Query: 997 FQGKPRPQVTWTKEGQPLA--GEEVSIRNSPTDTILFIR-AARRVHSGTYQVTVRIENME 1053
+ G+P P +TW GQ L E ++I N+ T L ++ R+ H+G Y+V +
Sbjct: 24280 YIGRPVPAMTWF-HGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGT 24338
Query: 1054 DKATLVLQVVDKPSPPQDLRVTDAWGLNVA-LEWKPPQDVGNTELWGYTVQKAD-KKTME 1111
A L +++ DKP P V +A N A + WKPP D G + + Y V+K + K+ E
Sbjct: 24339 VDAILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAE 24398
Query: 1112 WFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSD 1149
W V T C + L GYYFRV +QN G SD
Sbjct: 24399 WQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFGISD 24436
Score = 134 bits (337), Expect = 6e-31
Identities = 115/412 (27%), Positives = 167/412 (40%), Gaps = 57/412 (13%)
Query: 654 RIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVF 713
++ + V AG+ +RL+ + G P P V W K DA + T
Sbjct: 11834 KLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKD------------KDATDLTRSP----- 11876
Query: 714 DKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPD 773
RV+++T D S F++ A++ D G Y VT N G TV V+D P
Sbjct: 11877 ----------RVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPG 11926
Query: 774 APAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEA 833
KI +V D CTV W+PP DGG I YILE+ + K W + ++
Sbjct: 11927 PVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTP-GTTV 11985
Query: 834 RRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PIGPPSEPTHLAVEDVSDTTVSLKW 890
R+IEG Y RV A N IG P+ S+P + P P V VS +++ W
Sbjct: 11986 TRLIEGNEYIFRVRAENKIGTGPPT-ESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVW 12044
Query: 891 RPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMA 950
PPE G + GY +E + + WV + + V++L FRV+A N
Sbjct: 12045 NPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEI 12104
Query: 951 GPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKE 1010
G G P + PV ++ ++ P G P N + K + W K
Sbjct: 12105 GIGEPSLPSRPVVAKDPIEPP----------------GPPTNFRVVDTTKHSITLGWGKP 12148
Query: 1011 ----GQPLAGEEVSIR-----NSPTDTILFIRAARRVHSGTYQVTVRIENME 1053
G P+ G V +R SP + AA ++ + VT EN E
Sbjct: 12149 VYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQE 12200
Score = 132 bits (333), Expect = 2e-30
Identities = 101/340 (29%), Positives = 154/340 (45%), Gaps = 19/340 (5%)
Query: 649 LDCPGRIPDT-IVVVAGNKLRLDVPISGDPAPTVIWQKA--ITQGNKAPARPAPDAPEDT 705
+D P I T + V G+++ LD ISG P PT+ W K + + R AP
Sbjct: 8306 IDAPKVILRTSLEVKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRK 8365
Query: 706 GDSDEWVFDKKLLCETEGRVRVETTKD-RSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNL 764
G+ E ++ + R+ ++ +K S V + + D G+Y + V+N G +
Sbjct: 8366 GEVQE---EEPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPC 8422
Query: 765 TVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILER--KKKKSYRWMRLN 822
TV V+D P P ++ + S +WEPP DGG I+ Y LE+ K K W+ +
Sbjct: 8423 TVSVLDTPGPPINFVFEDIRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWIVVT 8482
Query: 823 FDLIQELSHEARRMIEGVVYEMRVYAVNAIG-----MSRPSPASQPFMPIGPPSEPTHLA 877
++ + ++IEG Y RV A N G +S+P A PF GPP P
Sbjct: 8483 -STLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKPLVAKDPF---GPPDAPDKPI 8538
Query: 878 VEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTG 937
VEDV+ ++ +KW P+ G+ L GY +E + W + L V L G
Sbjct: 8539 VEDVTSNSMLVKWNEPKDNGSPIL-GYWLEKREVNSTHWSRVNKSLLNALKANVDGLLEG 8597
Query: 938 ARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPR 977
+FRV A N AGPG ++P T + + P +PR
Sbjct: 8598 LTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIPR 8637
Score = 132 bits (331), Expect = 3e-30
Identities = 116/487 (23%), Positives = 193/487 (39%), Gaps = 56/487 (11%)
Query: 547 VYQSIADLMVGAKDQAVFKCEVSDENVRGV-WLKNGKELVPDSRIKVSHIGRVHKLTIDD 605
+ + + D+ + A C++ + + W + GKEL+ + K+S GR H LT+
Sbjct: 24163 IRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMT 24222
Query: 606 VTPADEADYSFVP--EGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVA 663
DE Y+ + E S+KL Q P+ H P + +
Sbjct: 24223 EEQEDEGVYTCIATNEVGEVETSSKLLL----------QATPQFHPGYP--LKEKYYGAV 24270
Query: 664 GNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEG 723
G+ LRL V G P P + W F + L +
Sbjct: 24271 GSTLRLHVMYIGRPVPAMTW-----------------------------FHGQKLLQNSE 24301
Query: 724 RVRVETTKDRSIFTVEGAEKEDE-GVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAP-KIS 781
+ +E T+ + ++ +++ G Y V + N G L V++ D PD P P I
Sbjct: 24302 NITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIE 24361
Query: 782 NVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVV 841
+ ++S + W+PPA DGG I Y++E+ + K +L I + + E
Sbjct: 24362 ALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAG 24421
Query: 842 YEMRVYAVNAIGMSRPSPAS------QPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPER 895
Y RV A N G+S P S PF G P +PT AV D+ V + W+PP
Sbjct: 24422 YYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAV--TKDSCV-VAWKPPAS 24478
Query: 896 VGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAP 955
G + Y +E + ++W++ T VK+L G FRV+ N+ G
Sbjct: 24479 DGGAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEW 24538
Query: 956 VTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLA 1015
+EP+T + + LR + + L+ G P+P V W ++G+ +
Sbjct: 24539 SEISEPITPKSDVPIQAPHFKEELR-NLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEII 24597
Query: 1016 GEEVSIR 1022
+ + R
Sbjct: 24598 ADGLKYR 24604
Score = 131 bits (329), Expect = 5e-30
Identities = 95/310 (30%), Positives = 133/310 (42%), Gaps = 39/310 (12%)
Query: 657 DTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKK 716
+T V+AG L++DVP G P P V W K D
Sbjct: 15783 NTFTVLAGEDLKVDVPFIGRPTPAVTWHK----------------------------DNV 15814
Query: 717 LLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPA 776
L +T RV E+T++ S+ T++ A +ED G Y V + N GE L V V+D P P
Sbjct: 15815 PLKQTT-RVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPPT 15873
Query: 777 AP-KISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARR 835
P K+ V DS T+ W PP YDGG I YI+E++ + W ++ + + +A R
Sbjct: 15874 GPVKMDEVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTWQIVSAT-VARTTIKACR 15932
Query: 836 MIEGVVYEMRVYAVNAIGMS-----RPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKW 890
+ G Y+ R+ A N G S P+ A PF GPP P V S ++ ++W
Sbjct: 15933 LKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPV---VTLSSRDSMEVQW 15989
Query: 891 RPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMA 950
P G + GY +E WV + T L G FRV A N+
Sbjct: 15990 NEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIV 16049
Query: 951 GPGAPVTTTE 960
G G P +E
Sbjct: 16050 GIGKPSKVSE 16059
Score = 130 bits (328), Expect = 6e-30
Identities = 94/317 (29%), Positives = 141/317 (44%), Gaps = 37/317 (11%)
Query: 643 EPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAP 702
+PP+I +D + DTIVV AG ++D I G P PT+ W K
Sbjct: 16167 DPPRISMD--PKYKDTIVVHAGESFKVDADIYGKPIPTIQWIK----------------- 16207
Query: 703 EDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQV 762
GD + R+ +++T + +V+ A + D G Y + KN GE V
Sbjct: 16208 ---GDQE---------LSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSV 16255
Query: 763 NLTVKVIDVPDAPAAP-KISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRL 821
+ VKV+D P P P IS V + CT+ W+PP DGG I+ YI+ER++ W +
Sbjct: 16256 TVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVV 16315
Query: 822 NFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGP---PSEPTHLAV 878
+ + +Q LS + +++EG Y R+ AVN G+ P S+P + P P P V
Sbjct: 16316 DAN-VQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPL-ESEPVVAKNPFVVPDAPKAPEV 16373
Query: 879 EDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGA 938
V+ ++ + W P G + GY +E + W + L + V L
Sbjct: 16374 TTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENH 16433
Query: 939 RLLFRVRAHNMAGPGAP 955
FRV A N AG P
Sbjct: 16434 DYEFRVSAENAAGLSEP 16450
Score = 128 bits (321), Expect = 4e-29
Identities = 99/421 (23%), Positives = 172/421 (40%), Gaps = 64/421 (15%)
Query: 644 PPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPE 703
PP+I L + + V AG + LD + G P PTV W+K
Sbjct: 12920 PPRIDLSVA--MKSLLTVKAGTNVCLDATVFGKPMPTVSWKK------------------ 12959
Query: 704 DTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVE--GAEKEDEGVYTVTVKNPVGEDQ 761
D LL EG ++ R++ T+E ++D G YT+T +N G
Sbjct: 12960 ----------DGTLLKPAEG---IKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKS 13006
Query: 762 VNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRL 821
+ +KV+D P PA+ KI+ + D + WEPP DGG I YI+++++ W ++
Sbjct: 13007 ATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNWAQV 13066
Query: 822 NFDLIQELSHEARRMIEGVVYEMRVYAVNAIGM-----SRPSPASQPFMPIGPPSEPTHL 876
+ + S ++IEG Y+ R+ A N G+ + P+ A P+ P G P
Sbjct: 13067 S-ATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPP--- 13122
Query: 877 AVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPT 936
+ +++ +++ W+PP G + GY +E W + ++ L
Sbjct: 13123 VISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQE 13182
Query: 937 GARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIP 996
G FRV A N AGPG P ++ ++ P G P +
Sbjct: 13183 GTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPP----------------GPPAFPKVY 13226
Query: 997 FQGKPRPQVTWTKE----GQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENM 1052
+ ++W K G P+ G V ++ + +D + + + ++VT +E+
Sbjct: 13227 DTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMEDT 13286
Query: 1053 E 1053
+
Sbjct: 13287 Q 13287
Score = 127 bits (320), Expect = 5e-29
Identities = 107/389 (27%), Positives = 163/389 (41%), Gaps = 50/389 (12%)
Query: 365 FQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTIS 424
F K LE V +G L E++ +A+VKW KNG EI + KY + G R L I
Sbjct: 5915 FTKPLEDQ-TVEEGATAVLECEVSRENAKVKWFKNGTEI-LKSKKYEIVADGRVRKLVIH 5972
Query: 425 QCSLADDAAYQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQV 484
C+ D Y C K S L V P V RPL D V + FECE+S E A+V
Sbjct: 5973 DCTPEDIKTYTCDAKDFKTSCNLNVVPPHVEFLRPLTDLQVREKEMARFECELSRENAKV 6032
Query: 485 KWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKK 544
KW KDG E+ + + KY G L+IN+ +L+D Y+ + L V E++
Sbjct: 6033 KWFKDGAEIKKGK--KYDIISKGAVRILVINKCLLDDEAEYSCEVRTARTSGMLTVLEEE 6090
Query: 545 LEVYQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTID 604
+++A++ V D CEVS +W K +E++ R ++ GR L I
Sbjct: 6091 AVFTKNLANIEVSETDTIKLVCEVSKPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQ 6150
Query: 605 DVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAG 664
+ D +Y+ + K+H E+ +F+ + P + ++ G
Sbjct: 6151 NAHLEDAGNYNCRLPSSRTDGKVKVH--ELAAEFISK--------------PQNLEILEG 6194
Query: 665 NKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGR 724
K IS + P V W++ D ++GD + + D G+
Sbjct: 6195 EKAEFVCSISKESFP-VQWKR-------------DDKTLESGDKYDVIAD--------GK 6232
Query: 725 VRVETTKDRSIFTVEGAEKEDEGVYTVTV 753
RV KD ++ +D G Y V V
Sbjct: 6233 KRVLVVKDATL--------QDMGTYVVMV 6253
Score = 127 bits (318), Expect = 9e-29
Identities = 91/356 (25%), Positives = 152/356 (42%), Gaps = 39/356 (10%)
Query: 643 EPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAP 702
E P+I +D R DTIVV AG RL+ + G P PT+ W +
Sbjct: 17249 ELPRISMDPKFR--DTIVVNAGETFRLEADVHGKPLPTIEWLRG---------------- 17290
Query: 703 EDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQV 762
DK++ E R ++ T +++ V+ A + D G Y + N G
Sbjct: 17291 -----------DKEI--EESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSF 17337
Query: 763 NLTVKVIDVPDAPAAP-KISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRL 821
+ VKV+D P P P +++ V + C++ W PP DGG I Y++E+++ W +
Sbjct: 17338 PVNVKVLDRPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISHYVVEKRETSRLAWTVV 17397
Query: 822 NFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM--PIGPPSEPTHLAVE 879
+++ S + +++EG Y R+ AVN G+ P ++ M P P P L V
Sbjct: 17398 ASEVVTN-SLKVTKLLEGNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVT 17456
Query: 880 DVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGAR 939
+++ ++++ W P+ G + GY VE W+ + + V L
Sbjct: 17457 NIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHE 17516
Query: 940 LLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKV----GEPV 991
FRV A N AG G P T + + +P H+ T + + G+P+
Sbjct: 17517 YEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPI 17572
Score = 127 bits (318), Expect = 9e-29
Identities = 97/336 (28%), Positives = 144/336 (42%), Gaps = 38/336 (11%)
Query: 640 PRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAP 699
P+ EP D G I AG+ +DVPISG PAP V W+
Sbjct: 22269 PQIEPTA---DLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWK--------------- 22310
Query: 700 DAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGE 759
++ L ET+ RV + TTKDR+ TV+ + + D G Y +T++N G
Sbjct: 22311 -------------LEEMRLKETD-RVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGV 22356
Query: 760 DQVNLTVKVIDVPDAPAAP-KISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRW 818
++TV VI P P ++S+V +SC + W P GG I YI+E+++ + W
Sbjct: 22357 KTFSVTVVVIGRPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAW 22416
Query: 819 MRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PIGPPSEPTH 875
+N ++ + + + + Y RV + N G+S+P S P + P PPS PT
Sbjct: 22417 QLVNSS-VKRTQIKVTHLTKYMEYSFRVSSENRFGVSKPLE-SAPIIAEHPFVPPSAPTR 22474
Query: 876 LAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLP 935
V VS +S++W P G + GY VE WV + + V L
Sbjct: 22475 PEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLV 22534
Query: 936 TGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRP 971
G FR A N AG + P+ Q + P
Sbjct: 22535 EGLEYQFRTYALNAAGVSKASEASRPIMAQNPVDAP 22570
Score = 124 bits (312), Expect = 4e-28
Identities = 103/421 (24%), Positives = 167/421 (39%), Gaps = 57/421 (13%)
Query: 643 EPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAP 702
E PKI +D + DT+++ AG RL+ +SG P PT+ W K
Sbjct: 15085 EAPKIKVDV--KFKDTVILKAGEAFRLEADVSGRPPPTMEWSK----------------- 15125
Query: 703 EDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQV 762
D K L E ++ ++ + + + + D G YT+T NP G +
Sbjct: 15126 -----------DGKEL-EGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGGFAKH 15173
Query: 763 NLTVKVIDVPDAPAAP-KISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRL 821
VKV+D P P P ++ V + C + W PP DGG I YI+++++ W +
Sbjct: 15174 IFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNV 15233
Query: 822 NFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PIGPPSEPTHLAV 878
+ +Q + ++++G Y RV AVN G+ P S+P + P GPP P + V
Sbjct: 15234 ASE-VQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPL-ESEPVLAVNPYGPPDPPKNPEV 15291
Query: 879 EDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGA 938
++ ++ + W P+ G + Y VE + W+ + V L G
Sbjct: 15292 TTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGH 15351
Query: 939 RLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQ 998
FR+ A N AG AP T+ + + +P G P N +
Sbjct: 15352 EYEFRIMAENAAGISAPSPTSPFYKACDTVFKP----------------GPPGNPRVLDT 15395
Query: 999 GKPRPQVTWTKE----GQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMED 1054
+ + W K G + G V I D + + + +Y +T EN E
Sbjct: 15396 SRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKATSYTITGLTENQEY 15455
Query: 1055 K 1055
K
Sbjct: 15456 K 15456
Score = 123 bits (309), Expect = 1e-27
Identities = 133/548 (24%), Positives = 211/548 (38%), Gaps = 60/548 (10%)
Query: 739 EGAEKEDEGVYTVTVKNPVGEDQVNLTVKVID------VPDAPAAPKISNVGEDSCTVQW 792
EG E E Y V +N G + T +I +P P+ PKI + G+ + T+ W
Sbjct: 19677 EGCEYE----YRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAW 19732
Query: 793 EPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAI 852
P +DGG PI GY +E KK W + + ++ + + G Y RV +VN +
Sbjct: 19733 VKPLFDGGAPITGYTVEYKKSDDTDW-KTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKV 19791
Query: 853 GMSRPSPASQPFMPIGPPSEPTHLAVEDVSDT-----------TVSLKWRPPERV--GAG 899
G S PS +S P + EP ++ T TV + RP V
Sbjct: 19792 GASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKP 19851
Query: 900 GLDGYSVEYCPEGCSEWVAALQGLTEHTS----ILVKDLPTGARLLFRVRAHNMAGPGAP 955
D + Y S ++ + S + ++++ + A L V+ + GP
Sbjct: 19852 DTDLRTRAYVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGPPTN 19911
Query: 956 VTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLA 1015
+T + +L +P + G PV + + + W
Sbjct: 19912 ITVQDVTKESAVLS---WDVP-------ENDGGAPVKNY-HIEKREASKKAWVSVTNNCN 19960
Query: 1016 GEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVT 1075
+ N I + R + G V + E E +++ +KPSPP+ L VT
Sbjct: 19961 RLSYKVTNLQEGAIYYFRVSGENEFG---VGIPAETKEG-----VKITEKPSPPEKLGVT 20012
Query: 1076 DAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGY 1135
+V+L W P+ G + + Y V+ +K W + TH VV L + Y
Sbjct: 20013 SISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQKNWVKCAVA-KSTHHVVSGLRENSEY 20071
Query: 1136 YFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAG 1195
+FRVF++N G SD PV I EPP +D PS T V AG
Sbjct: 20072 FFRVFAENQAGLSDPRELLL-PVLIKEQ---LEPPE---IDMKNFPSHTV-----YVRAG 20119
Query: 1196 YTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRA 1255
+ + G P PK++ ++G+ L RF LT+ +++ D G Y A
Sbjct: 20120 SNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITA 20179
Query: 1256 TNLQGEAR 1263
N G +
Sbjct: 20180 ANSSGTTK 20187
Score = 121 bits (304), Expect = 4e-27
Identities = 84/310 (27%), Positives = 131/310 (42%), Gaps = 39/310 (12%)
Query: 657 DTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKK 716
+T + AG L++++P+ G P P + W K D +
Sbjct: 17947 NTYSIQAGEDLKIEIPVIGRPRPNISWVK----------------------------DGE 17978
Query: 717 LLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPA 776
L +T RV VE T ++ ++ K+D G YTVT N G NL+V V++ P P
Sbjct: 17979 PLKQTT-RVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGPPV 18037
Query: 777 AP-KISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARR 835
P + V D + WEPPAY GG I YI+E++ + W ++ + + + +
Sbjct: 18038 GPVRFDEVSADFVVISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVSAT-VARTTIKITK 18096
Query: 836 MIEGVVYEMRVYAVNAIGMSRPSPASQ-----PFMPIGPPSEPTHLAVEDVSDTTVSLKW 890
+ G Y+ R++A N G S P + PF GPP P V +S + ++W
Sbjct: 18097 LKTGTEYQFRIFAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPF---VTSISKDQMLVQW 18153
Query: 891 RPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMA 950
P G + GY +E + WV + + T L G F+V A N+
Sbjct: 18154 HEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIV 18213
Query: 951 GPGAPVTTTE 960
G G P +E
Sbjct: 18214 GIGKPSKVSE 18223
Score = 121 bits (304), Expect = 4e-27
Identities = 89/349 (25%), Positives = 156/349 (44%), Gaps = 15/349 (4%)
Query: 738 VEGAEKEDEGVYTVTVKNPVG-----EDQVNLTVKV-IDVPDAPA-APKISNVGEDSCTV 790
V+G ++ E + V+ +N G + + +T K ++ P+ P+ P++ +V + S ++
Sbjct: 23917 VKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSL 23976
Query: 791 QWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVN 850
W P DGG + GY +ERK+ + +W+R N I + ++ Y+ R+ A N
Sbjct: 23977 SWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQFRIIAQN 24036
Query: 851 AIGMSRPSPASQPFM---PIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVE 907
+G+S SPAS+P + P PS+P L + +S +V+L+W PE G + GY VE
Sbjct: 24037 DVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVE 24096
Query: 908 YCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEI 967
Y G S W + + + + L FRV A N G P T ++++
Sbjct: 24097 YRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYEFRVFAENETGLSRPRRTA--MSIKTK 24154
Query: 968 LQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPL-AGEEVSIRNSPT 1026
L R + + K+GE L G+P P + W + G+ L + + +
Sbjct: 24155 LTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGR 24214
Query: 1027 DTILFIRAARRVHSGTYQ--VTVRIENMEDKATLVLQVVDKPSPPQDLR 1073
L + + G Y T + +E + L+LQ + P L+
Sbjct: 24215 THTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLK 24263
Score = 121 bits (303), Expect = 5e-27
Identities = 99/388 (25%), Positives = 160/388 (41%), Gaps = 45/388 (11%)
Query: 480 EGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELI 539
E Q KW+ E RE F + +G + + L ++ + +++
Sbjct: 24493 EKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSDVP 24552
Query: 540 VQEKKLEVYQSIADLMVGAKDQAVFKCEVSDENVRGV-WLKNGKELVPDS-RIKVSHI-G 596
+Q + + + +L V + A C+V+ V W + GKE++ D + ++ G
Sbjct: 24553 IQAPHFK--EELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKG 24610
Query: 597 RVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIP 656
H+L I VT D Y ++S +EV++ P KIHL
Sbjct: 24611 GYHQLIIASVTDDDATVYQVRATNQGGSVSGTAS-LEVEV-------PAKIHLPKTLEGM 24662
Query: 657 DTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKK 716
+ + G + + +P SG P P + WQK +
Sbjct: 24663 GAVHALRGEVVSIKIPFSGKPDPVITWQKG-----------------------------Q 24693
Query: 717 LLCETEGRVRVETTKD-RSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAP 775
L + G +V T+ S+ G E++D G Y V KN G DQ + + V DVPD P
Sbjct: 24694 DLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPP 24753
Query: 776 AAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARR 835
K+S+V DS + W PA DGG I YI+E+ + RW+R+ +E +
Sbjct: 24754 RGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVG--QARETRYTVIN 24811
Query: 836 MIEGVVYEMRVYAVNAIGMSRPSPASQP 863
+ Y+ RV A N G+S+PS S+P
Sbjct: 24812 LFGKTSYQFRVIAENKFGLSKPSEPSEP 24839
Score = 120 bits (301), Expect = 8e-27
Identities = 94/330 (28%), Positives = 139/330 (42%), Gaps = 42/330 (12%)
Query: 644 PPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPE 703
PPK LD D + + AG+ L LD + G P P +IW K
Sbjct: 22671 PPKAELDARLH-GDLVTIRAGSDLVLDAAVGGKPEPKIIWTKG----------------- 22712
Query: 704 DTGDSDEWVFDKKL-LCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQV 762
DK+L LCE +V ++ T R+ ++ ++ D G YT+TVKN G V
Sbjct: 22713 ----------DKELDLCE---KVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAV 22759
Query: 763 NLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLN 822
++ VKV+D P +S V ++ CT+ W P DGG I YI+ER++ W+ +
Sbjct: 22760 SVMVKVLDSPGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLNWVIVE 22819
Query: 823 FDLIQELSHEARRMIEGVVYEMRVYAVNAIG-----MSRPSPASQPFMPIGPPSEPTHLA 877
+ LS+ R+I+ Y RV AVN G S P A F PP P +
Sbjct: 22820 GE-CPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVG 22878
Query: 878 VEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEH-TSILVKDLPT 936
+ ++W PE G + Y V+ + W + + T + V L
Sbjct: 22879 ---TGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLME 22935
Query: 937 GARLLFRVRAHNMAGPGAPVTTTEPVTVQE 966
G FRV A N AG P + ++ +E
Sbjct: 22936 GCDYQFRVTAVNAAGNSEPSEASNFISCRE 22965
Score = 119 bits (298), Expect = 2e-26
Identities = 80/274 (29%), Positives = 134/274 (48%), Gaps = 6/274 (2%)
Query: 365 FQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTIS 424
F KL+ V K I L E++ DA VKW K+G+EI+ S + I ++ G KR L +
Sbjct: 5648 FTGKLQDYTGVEKDEVI-LQCEISKADAPVKWFKDGKEIKPSKNAVI-KADGKKRMLILK 5705
Query: 425 QCSLADDAAYQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQV 484
+ +D Y C G +K S +L +++ + + RPL VM + FE E+SE+
Sbjct: 5706 KALKSDIGQYTCDCGTDKTSGKLDIEDREIKLVRPLHSVEVMETETARFETEISEDDIHA 5765
Query: 485 KWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKK 544
W G L +T K++G+ H L+++ L+ G + ++ A L V+ +
Sbjct: 5766 NWKLKGEALL--QTPDCEIKEEGKIHSLVLHNCRLDQTGGVDFQAANVKSSAHLRVKPRV 5823
Query: 545 LEVYQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTID 604
+ + + + D+ V A + A F CE+S E++ W GK+L P ++ G+VH LT+
Sbjct: 5824 IGLLRPLKDVTVTAGETATFDCELSYEDIPVEWYLKGKKLEPSDKVVPRSEGKVHTLTLR 5883
Query: 605 DVTPADEADYSFVPEGFACNLSAKLHFMEVKIDF 638
DV D + + F + A L E ++F
Sbjct: 5884 DVKLEDAGEVQLTAKDFKTH--ANLFVKEPPVEF 5915
Score = 119 bits (297), Expect = 2e-26
Identities = 81/306 (26%), Positives = 131/306 (42%), Gaps = 39/306 (12%)
Query: 661 VVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCE 720
V G L+++VPISG P PT+ W K D L +
Sbjct: 16869 VQVGQDLKIEVPISGRPKPTITWTK----------------------------DGLPLKQ 16900
Query: 721 TEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAP-K 779
T R+ V + D + +++ K+D G Y +TV N VG+ ++ + +D PD P P K
Sbjct: 16901 TT-RINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVK 16959
Query: 780 ISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEG 839
+V +S T+ W PP Y GG I YI++++ + W ++ + + + ++ G
Sbjct: 16960 FDDVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSAT-VARTTLKVTKLKTG 17018
Query: 840 VVYEMRVYAVNAIGMS-----RPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPE 894
Y+ R++A N G S P A P+ GPP P A+ S ++ ++W P
Sbjct: 17019 TEYQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAI---SKDSMVIQWHEPV 17075
Query: 895 RVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGA 954
G + GY +E W + + T ++L G FRV A N+ G G
Sbjct: 17076 NNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGK 17135
Query: 955 PVTTTE 960
+E
Sbjct: 17136 ASKNSE 17141
Score = 118 bits (295), Expect = 4e-26
Identities = 111/440 (25%), Positives = 189/440 (42%), Gaps = 60/440 (13%)
Query: 395 KWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCSTELFVKEPPV 454
KWLKNG EI+ S K + +L I D A Y V G + L+V+ +
Sbjct: 2954 KWLKNGVEIK-STDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHI 3012
Query: 455 LITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLII 514
+ ++D V+ +R FECEVSE V+W+KD EL + T + + +K+ H L+I
Sbjct: 3013 EFRKHIKDIKVLEKKRAMFECEVSEPDITVQWMKDDQEL--QITDRIKIQKEKYVHRLLI 3070
Query: 515 NEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDENVR 574
+ DAG Y + G + A+L V+ + + + ++ V K +AV + EV++++V
Sbjct: 3071 PSTRMSDAGKYTVVAGGNVSTAKLFVEGRDVRIRSIKKEVQVIEKQRAVVEFEVNEDDVD 3130
Query: 575 GVWLKNGKEL--VPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFM 632
W K+G E+ R K R+H++ I + +D +Y+FV +++
Sbjct: 3131 AHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVTL----- 3185
Query: 633 EVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNK 692
+V EPP++ + + V +G R ISG P P + W K
Sbjct: 3186 -----YVNAPEPPQVLQEL-----QPVTVQSGKPARFCAVISGRPQPKISWYK------- 3228
Query: 693 APARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVT 752
+E + C+ + ++ ++ +E A ED VYT
Sbjct: 3229 ----------------EEQLLSTGFKCKF-----LHDGQEYTLLLIE-AFPEDAAVYTCE 3266
Query: 753 VKNPVG--EDQVNLTVKVIDV--PDAPA---APKISNVGEDSCTVQWEPPAY----DGGQ 801
KN G +L+V+V +V PD P I +D+ T + +P + G
Sbjct: 3267 AKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTD 3326
Query: 802 PILGYILERKKKKSYRWMRL 821
+ + + KK K R+ R+
Sbjct: 3327 LKVSWYSKDKKIKPSRFFRM 3346
Score = 118 bits (295), Expect = 4e-26
Identities = 86/275 (31%), Positives = 130/275 (47%), Gaps = 7/275 (2%)
Query: 365 FQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTIS 424
F KL V K +I L E++ D VKW K+G+EI S KY ++ G +R L I
Sbjct: 5293 FTVKLHDKTAVEKD-EITLKCEVSK-DVPVKWFKDGEEIVPS-PKYSIKADGLRRILKIK 5349
Query: 425 QCSLADDAAYQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQV 484
+ L D Y C G +K + V+ + + +PL V VG+ FE E+SE
Sbjct: 5350 KADLKDKGEYVCDCGTDKTKANVTVEARLIKVEKPLYGVEVFVGETAHFEIELSEPDVHG 5409
Query: 485 KWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKK 544
+W G LT + +DG++H LI++ L G + + ++ A L V+E
Sbjct: 5410 QWKLKGQPLTASPDCE--IIEDGKKHILILHNCQLGMTGEVSFQAANAKSAANLKVKELP 5467
Query: 545 LEVYQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTID 604
L ++D+ V KD+A F+CEVS E WLK +E+ D R ++ G H + I
Sbjct: 5468 LIFITPLSDVKVFEKDEAKFECEVSREPKTFRWLKGTQEITGDDRFELIKDGTKHSMVIK 5527
Query: 605 DVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFV 639
DEA Y F E + S KL +++ F+
Sbjct: 5528 SAAFEDEAKYMFEAED--KHTSGKLIIEGIRLKFL 5560
Score = 117 bits (294), Expect = 5e-26
Identities = 82/248 (33%), Positives = 119/248 (47%), Gaps = 8/248 (3%)
Query: 386 ELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCST 445
E++ + WLKNG EI+MS K+ G L I S D A Y V G ++ S
Sbjct: 2858 EVSHFNVPSMWLKNGVEIEMS-EKFKIVVQGKLHQLIIMNTSTEDSAEYTFVCGNDQVSA 2916
Query: 446 ELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKK 505
L V P++IT L+D + FE V+ EG KWLK+GVE+ + + R KK
Sbjct: 2917 TLTVT--PIMITSMLKDINAEEKDTITFEVTVNYEGISYKWLKNGVEIKSTDKCQMRTKK 2974
Query: 506 DGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFK 565
H L I DA Y + A L V+ + +E + I D+ V K +A+F+
Sbjct: 2975 --LTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIEFRKHIKDIKVLEKKRAMFE 3032
Query: 566 CEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNL 625
CEVS+ ++ W+K+ +EL RIK+ VH+L I +D Y+ V G N+
Sbjct: 3033 CEVSEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVAGG---NV 3089
Query: 626 SAKLHFME 633
S F+E
Sbjct: 3090 STAKLFVE 3097
Score = 117 bits (294), Expect = 5e-26
Identities = 76/266 (28%), Positives = 117/266 (43%), Gaps = 7/266 (2%)
Query: 370 EPAY--QVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCS 427
+P Y +V G +EL++ D +W GQ + S I E G K L + C
Sbjct: 5383 KPLYGVEVFVGETAHFEIELSEPDVHGQWKLKGQPLTASPDCEIIED-GKKHILILHNCQ 5441
Query: 428 LADDAAYQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWL 487
L K + L VKE P++ PL D V +FECEVS E +WL
Sbjct: 5442 LGMTGEVSFQAANAKSAANLKVKELPLIFITPLSDVKVFEKDEAKFECEVSREPKTFRWL 5501
Query: 488 KDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEV 547
K E+T ++ F+ KDG +H ++I A ED Y +LI++ +L+
Sbjct: 5502 KGTQEITGDDRFE--LIKDGTKHSMVIKSAAFEDEAKYMFEAEDKHTSGKLIIEGIRLKF 5559
Query: 548 YQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVT 607
+ D+ K+ AVF E+S +N+R W KN + L + + G+ H +T D++
Sbjct: 5560 LTPLKDVTAKEKESAVFTVELSHDNIRVKWFKNDQRLHTTRSVSMQDEGKTHSITFKDLS 5619
Query: 608 PADEADYSFVPEGFACNLSAKLHFME 633
D + E + AKL +E
Sbjct: 5620 IDDTSQIRV--EAMGMSSEAKLTVLE 5643
Score = 115 bits (289), Expect = 2e-25
Identities = 84/310 (27%), Positives = 138/310 (44%), Gaps = 12/310 (3%)
Query: 360 KKSTAFQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKR 419
K+ F ++L+ K E ++ +VKW K+G E+ G KY S
Sbjct: 2125 KQLITFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVH-EGDKYRMHSDRKVH 2183
Query: 420 TLTISQCSLADDAAYQCVVGGE---KCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECE 476
L+I +D Y CV+ + K + +L V+ V + L+D V E EC
Sbjct: 2184 FLSILTIDTSDAEDYSCVLVEDENVKTTAKLIVEGAVVEFVKELQDIEVPESYSGELECI 2243
Query: 477 VSEEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALA 536
VS E + KW + VEL + KY R +L + + ED G Y+ G +
Sbjct: 2244 VSPENIEGKWYHNDVEL--KSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGKKTTC 2301
Query: 537 ELIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIG 596
+L ++ + + + Q ++D V D + +VS E+V GVW+K+G+E+ P R+ +
Sbjct: 2302 KLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHIVIDK 2361
Query: 597 RVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQ-----EPPKIHLDC 651
+ H L I+D+T D +YSF + S ++ V + P + E K L+C
Sbjct: 2362 QSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVDV-ITPLKDVNVIEGTKAVLEC 2420
Query: 652 PGRIPDTIVV 661
+PD V
Sbjct: 2421 KVSVPDVTSV 2430
Score = 114 bits (285), Expect = 6e-25
Identities = 99/408 (24%), Positives = 161/408 (39%), Gaps = 59/408 (14%)
Query: 649 LDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDS 708
+D P + + AG ++L ISG PAPT+ W K
Sbjct: 20500 IDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKD---------------------- 20537
Query: 709 DEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKV 768
DK+L +T V VE T D + ++ A++ + G Y + ++N +G + V++
Sbjct: 20538 -----DKEL--QTNALVCVENTTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQI 20590
Query: 769 IDVPDAPAAP-KISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQ 827
+D P P P + V + T+ W PPA DGG I YI+E+++ W ++ + ++
Sbjct: 20591 LDKPGPPGGPIEFKTVTAEKITLLWRPPADDGGAKITHYIVEKRETSRVVWSMVS-EHLE 20649
Query: 828 ELSHEARRMIEGVVYEMRVYAVNAIGMSRPSP-----ASQPFMPIGPPSEPTHLAVEDVS 882
E ++I+G Y RV AVN G+ P A F+ GPP P V ++
Sbjct: 20650 ECIITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIP---EVTKIT 20706
Query: 883 DTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLF 942
++++ W P G + GY +E + W L+ T V L + +
Sbjct: 20707 KNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQY 20766
Query: 943 RVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPR 1002
RV A N AG G +E + + P G P + I K
Sbjct: 20767 RVCAVNAAGQGPFSEPSEFYKAADPIDPP----------------GPPAKIRIADSTKSS 20810
Query: 1003 PQVTWTKE----GQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVT 1046
+ W+K G + G V IR + + V + Y V+
Sbjct: 20811 ITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVS 20858
Score = 112 bits (281), Expect = 2e-24
Identities = 106/428 (24%), Positives = 172/428 (40%), Gaps = 58/428 (13%)
Query: 867 IGPPSEPTH-LAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTE 925
IG P+ P L +D+ +V + WRPP G + GY +E + W +
Sbjct: 23853 IGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYT-IDSRVR 23911
Query: 926 HTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQK 985
TS++VK L FRV A N G P+ + EPVT + L P + P + + +
Sbjct: 23912 GTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPP--EPPSNPPEVLDV 23969
Query: 986 KVGEPVNLLIPFQGKPRPQVTWTKE----GQPLAGEEVSIRNSPTDTILFIRAAR-RVHS 1040
K ++W++ G + G + + + TD ++R + ++ +
Sbjct: 23970 T-------------KSSVSLSWSRPKDDGGSRVTGYYIERKETSTDK--WVRHNKTQITT 24014
Query: 1041 GTYQVTVRIENMEDKATLVLQ-------------------VVDKPSPPQDLRVTDAWGLN 1081
Y VT + + E + ++ Q DKPS P +L + +
Sbjct: 24015 TMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKDS 24074
Query: 1082 VALEWKPPQDVGNTELWGYTVQKADKKTMEWF-TVLEHYRRTHCVVPELIIGNGYYFRVF 1140
V L+W+ P+ G E+ GY V+ W + E + + L+ Y FRVF
Sbjct: 24075 VTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYEFRVF 24134
Query: 1141 SQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAML 1200
++N G S RP T K L EAP + + + + G A L
Sbjct: 24135 AENETGLS-------------RPRRTAMSIKTK-LTSGEAPGIRKEMKDVTTKLGEAAQL 24180
Query: 1201 CCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQG 1260
C + G P P I W++ G +L + +++M S TL + D G+Y C ATN G
Sbjct: 24181 SCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVG 24240
Query: 1261 EARCECRL 1268
E +L
Sbjct: 24241 EVETSSKL 24248
Score = 112 bits (280), Expect = 2e-24
Identities = 127/527 (24%), Positives = 203/527 (38%), Gaps = 79/527 (14%)
Query: 769 IDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFD-LIQ 827
I P P PK+ + ++ + W P DGG PILGY++E +K + +W R+N D LI+
Sbjct: 11429 IKPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKDELIR 11488
Query: 828 ELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMP---IGPPSEPTHLAVEDVSDT 884
+ + +IEG Y R+ A N +G P ++ + + PP + DV
Sbjct: 11489 QCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRDVITV 11548
Query: 885 TVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSI-LVKDLPTGARLLFR 943
V R RV PE W + L + L++DLP R+ +
Sbjct: 11549 RVGQTIRILARVKGR----------PEPDITWTKEGKVLVREKRVDLIQDLP---RVELQ 11595
Query: 944 VRAHNMAGPGAPVTTTEPVT-------VQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIP 996
++ A G + + + + + +L RP G NL +
Sbjct: 11596 IKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRP----------------GPCQNLKVT 11639
Query: 997 FQGKPRPQVTWTKE----GQPLAGEEVSIRNS--------PTDTILFIRAARRVHSGTYQ 1044
K ++W G + V R +D + A + + Y
Sbjct: 11640 NVTKENCTISWENPLDNGGSEITNFIVEYRKPNQKGWSIVASDVTKRLIKANLLANNEYY 11699
Query: 1045 VTVRIEN-------MEDKAT-LVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTE 1096
V EN +E K L + +D+P P++L + D V L+W+ P G +
Sbjct: 11700 FRVCAENKVGVGPTIETKTPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSP 11759
Query: 1097 LWGYTVQKADKKTMEWFTVLE-HYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTK 1155
Y V++ K + +W V + + TH +V + Y FRV ++N G SD T +
Sbjct: 11760 NLSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVENQIYEFRVQTKNEGGESDWVKTEE 11819
Query: 1156 EPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWF 1215
+ E LD + T V AG T L VRG P P+++W
Sbjct: 11820 V--------VVKEDLQKPVLDLKLSGVLT-------VKAGDTIRLEAGVRGKPFPEVAWT 11864
Query: 1216 --KNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQG 1260
K+ DL R ++ ++ + K DGG YV ATN G
Sbjct: 11865 KDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAG 11911
Score = 110 bits (274), Expect = 1e-23
Identities = 148/625 (23%), Positives = 238/625 (38%), Gaps = 79/625 (12%)
Query: 684 QKAITQGNKAPARPAPDAPEDTGDS-DEWVFDKKLLCETEGRVRVETTKD--------RS 734
Q +T+ K A + P D G ++ +K+ ET + TKD R
Sbjct: 10645 QPIVTEVTKDSALVTWNKPHDGGKPITNYILEKR---ETMSKRWARVTKDPIHPYTKFRV 10701
Query: 735 IFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDV------PDAPAAPKISNVGEDSC 788
+EG + E + V+ +N +G + K + P P P+ + +S
Sbjct: 10702 PDLLEGCQYE----FRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSV 10757
Query: 789 TVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNF--DLIQELSHEARRMIEGVVYEMRV 846
+ W+PP +DGG ILGYI+E +K W R N + E ++ + +G Y+ RV
Sbjct: 10758 DLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRV 10817
Query: 847 YAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSV 906
AVNA G S P+ +P + + EP L ++ +K R+ A +
Sbjct: 10818 LAVNAAGESDPAHVPEPVL-VKDRLEPPELILDANMAREQHIKVGDTLRLSA------II 10870
Query: 907 EYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQE 966
+ P W + T + P G++L R AH G + +T P +
Sbjct: 10871 KGVPFPKVTW--KKEDRDAPTKARIDVTPVGSKLEIRNAAHEDGGIYS-LTVENPAGSKT 10927
Query: 967 ILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKE----GQPLAGEEVSIR 1022
+ ++ + K G P +L + K +TW + G + V R
Sbjct: 10928 V----------SVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERR 10977
Query: 1023 N------SPTDTILFIRA--ARRVHSGT-YQVTVRIENMEDKATLV--------LQVVDK 1065
+ SP ++ A+ ++ G Y V EN + V L +
Sbjct: 10978 DVASAQWSPLSATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHP 11037
Query: 1066 PSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCV 1125
P PP+DL D V+L W P G + + GY V+ ++ T +W + CV
Sbjct: 11038 PGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIK-FKTVTNLECV 11096
Query: 1126 VPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQ 1185
V L G Y FRV ++N+VG T P+ + PP+ + LD +
Sbjct: 11097 VTGLQQGKTYRFRVKAENIVGLG--LPDTTIPIECQEKLV---PPSVE-LDV----KLIE 11146
Query: 1186 PLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCP 1245
LV V AG T +RG P P W +G ++ D + + + L I+
Sbjct: 11147 GLV---VKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLR 11203
Query: 1246 FDGGIYVCRATNLQGEARCECRLEV 1270
D G Y +N G L V
Sbjct: 11204 RDTGEYQITVSNAAGSKTVAVHLTV 11228
Score = 109 bits (272), Expect = 2e-23
Identities = 185/803 (23%), Positives = 284/803 (35%), Gaps = 153/803 (19%)
Query: 542 EKKLEVYQSIADLMVGAKDQAVFK-CEVSDENVRGVWLKN--GKELVPDSRIKVSHIGRV 598
+K+L++ + ++ G + AV K C+ SD + +KN G + V + G
Sbjct: 22713 DKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLDSPGPC 22772
Query: 599 HKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIH-LDCPGRIPD 657
KLT+ VT A +L + E+ V R+E +++ + G P
Sbjct: 22773 GKLTVSRVTQEKCT--------LAWSLPQEDGGAEITHYIVERRETSRLNWVIVEGECPT 22824
Query: 658 TIVVV--------------AGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPE 703
VV A NK VP+ +P I N P PE
Sbjct: 22825 LSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEP---------IVARNSFTIPSPPGIPE 22875
Query: 704 DTGDSDEWVFDKKLLCETEGRVRVET----------------TKDRSIFT--------VE 739
+ G E + + E++G + KD ++ +E
Sbjct: 22876 EVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLME 22935
Query: 740 GAEKEDEGVYTVTVKNPVGEDQVNLTVKVID------VPDAPAAPKISNVGEDSCTVQWE 793
G + + + VT N G + + I P P+AP++ + + S ++ W
Sbjct: 22936 GCDYQ----FRVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWT 22991
Query: 794 PPAYDGGQPILGYILERKKKKSYRWMRLNFDL-IQELSHEARRMIEGVVYEMRVYAVNAI 852
P YDGG I+GY+LE ++K + +W R++ + I+ + G Y RV AVN
Sbjct: 22992 KPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVK 23051
Query: 853 GMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTT-----------VSLKWRPPERVGAGGL 901
GMS S + P+ P +D+ T VS+ RPP
Sbjct: 23052 GMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIRAGASLRLMVSVSGRPPP------- 23104
Query: 902 DGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARL-LFRVRAHNMAGPGAPVTTTE 960
+ + +G A+ TE S+L+ D + + A N +G + +
Sbjct: 23105 ---VITWSKQGIDLASRAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVK 23161
Query: 961 PVTVQEILQRPRLQLPRHLRQTIQKKV-----GEPVNLLIPFQGKPRPQVTWTKEGQPLA 1015
+++ TI ++ G PVN I + +E A
Sbjct: 23162 VYDTPGPCPSVKVKEVSRDSVTITWEIPTIDGGAPVNNYIVEK----------REAAMRA 23211
Query: 1016 GEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENM--------EDKATLVLQVVDKPS 1067
+ V+ + S T R + V Y V EN+ A LV +V P
Sbjct: 23212 FKTVTTKCSKT----LYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSEV---PL 23264
Query: 1068 PPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWF-------TVLEHYR 1120
P L V D V L W+ P G + L GY ++ T W TVLEH
Sbjct: 23265 VPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEH-- 23322
Query: 1121 RTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEA 1180
V L G Y FR+ +QN G S+ PR +T D
Sbjct: 23323 ----TVTSLNEGEQYLFRIRAQNEKGVSE-----------PRETVTA----VTVQDLRVL 23363
Query: 1181 PSF---TQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLT 1237
P+ T P V AG L + G P P SWF G L E R + + V
Sbjct: 23364 PTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAK 23423
Query: 1238 LEIRKPCPFDGGIYVCRATNLQG 1260
L IR+ D G Y N+ G
Sbjct: 23424 LTIRETTIRDTGEYTLELKNVTG 23446
Score = 108 bits (270), Expect = 3e-23
Identities = 83/275 (30%), Positives = 134/275 (48%), Gaps = 11/275 (4%)
Query: 374 QVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAA 433
++ +G K ++ V+W ++ + ++ SG KY + G KR L + +L D
Sbjct: 6190 EILEGEKAEFVCSISKESFPVQWKRDDKTLE-SGDKYDVIADGKKRVLVVKDATLQDMGT 6248
Query: 434 YQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVEL 493
Y +VG + + L V E + I PL+D V Q V F CEV+ EGA+ KW ++ E
Sbjct: 6249 YVVMVGAARAAAHLTVIEK-LRIVVPLKDTRVKEQQEVVFNCEVNTEGAKAKWFRN--EE 6305
Query: 494 TREETFKYRFKKDGQRHHLIINEAMLEDAGHY--ALCTSGGQ---ALAELIVQEKKLEVY 548
++ KY + + L I +A L+D +Y +L G+ + A LIV+E+ L +
Sbjct: 6306 AIFDSSKYIILQKDLVYTLRIRDAHLDDQANYNVSLTNHRGENVKSAANLIVEEEDLRIV 6365
Query: 549 QSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTP 608
+ + D+ K F C+V+ NV W KNG+E+ D+R+ H LTI D
Sbjct: 6366 EPLKDIETMEKKSVTFWCKVNRLNVTLKWTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGF 6425
Query: 609 ADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQE 643
DE +Y V G ++ A+L +E +FV E
Sbjct: 6426 PDEGEY-IVTAGQDKSV-AELLIIEAPTEFVEHLE 6458
Score = 107 bits (268), Expect = 6e-23
Identities = 72/235 (30%), Positives = 117/235 (49%), Gaps = 8/235 (3%)
Query: 384 TVELADHDAE-VKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEK 442
TVEL + + V+W+KNG ++ S KY G +L I C++ D++ Y +G
Sbjct: 2681 TVELTHPNVKGVQWIKNGVVLE-SNEKYAISVKGTIYSLRIKNCAIVDESVYGFRLGRLG 2739
Query: 443 CSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYR 502
S L V+ V I + +D + V FE VS + VKW VE+ + K+R
Sbjct: 2740 ASARLHVET--VKIIKKPKDVTALENATVAFEVSVSHDTVPVKWFHKSVEIKPSD--KHR 2795
Query: 503 FKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQA 562
+ + H L++ DAG Y + A+L V+ L + +++ ++ V A
Sbjct: 2796 LVSERKVHKLMLQNISPSDAGEYTAVVGQLECKAKLFVET--LHITKTMKNIEVPETKTA 2853
Query: 563 VFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFV 617
F+CEVS NV +WLKNG E+ + K+ G++H+L I + + D A+Y+FV
Sbjct: 2854 SFECEVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFV 2908
Score = 107 bits (268), Expect = 6e-23
Identities = 98/412 (23%), Positives = 161/412 (39%), Gaps = 41/412 (9%)
Query: 868 GPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHT 927
GPP+ P ++ DV+ +++ W+PP+ G + Y VE W G ++ T
Sbjct: 11233 GPPTGPINIL--DVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSK-T 11289
Query: 928 SILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKV 987
+ + L G +FRVRA N G G P+ +T V + + P + + +
Sbjct: 11290 KLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVA------KHKFSPPSPPGKPVVTDI 11343
Query: 988 GE---PVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQ 1044
E V+ +P P + E + + G+ V + +P + F R TY+
Sbjct: 11344 TENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVNKTPIADLKF-RVTGLYEGNTYE 11402
Query: 1045 VTVRIENM--------EDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTE 1096
V EN+ + + P PP + ++ D L W P G +
Sbjct: 11403 FRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGGSP 11462
Query: 1097 LWGYTVQKADKKTMEWFTVLEHYRRTHCV--VPELIIGNGYYFRVFSQNMVGFSDRAATT 1154
+ GY V+ T +W + + C VP LI GN Y FR+ + N+VG +
Sbjct: 11463 ILGYVVECQKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELA 11522
Query: 1155 KEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIA---GYTAMLCCAVRGSPKPK 1211
+ + A D P + R VI G T + V+G P+P
Sbjct: 11523 ESVI---------------AKDILHPPEVELDVTCRDVITVRVGQTIRILARVKGRPEPD 11567
Query: 1212 ISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEAR 1263
I+W K G L + R + + L+I++ D G Y+ A N G A+
Sbjct: 11568 ITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSGHAQ 11619
Score = 106 bits (265), Expect = 1e-22
Identities = 124/571 (21%), Positives = 216/571 (37%), Gaps = 99/571 (17%)
Query: 736 FTVEGAEKEDEGVYTVTVKNPVGEDQVNLT---VKVIDV---PDAPAAPKISNVGEDSCT 789
+ V G + E + + +N G + T K D P P P++ + S +
Sbjct: 15342 YKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSIS 15401
Query: 790 VQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDL-IQELSHEARRMIEGVVYEMRVYA 848
+ W P YDGG I GY++E + W + ++ S+ + E Y++R+YA
Sbjct: 15402 IAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYA 15461
Query: 849 VNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTT----------------VSLKWRP 892
+N+ G+ P+ +P P +E L E D V +K RP
Sbjct: 15462 MNSEGLGEPA-----LVPGTPKAEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRP 15516
Query: 893 PERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGP 952
V G S++ A+++ + +T ++V ++ + + N +G
Sbjct: 15517 APEVKWARDHGESLDK---------ASIESTSSYTLLIVGNVNRFDSGKYILTVENSSGS 15567
Query: 953 GAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQ 1012
+ +L P G P +L + K +TW
Sbjct: 15568 KSAFVNVR------VLDTP----------------GPPQDLKVKEVTKTSVTLTWDP--- 15602
Query: 1013 PLAGEEVSIRNSPTDTILFIRAA-RRVHSGTYQVTVRIENMEDKATLVLQVV-------- 1063
PL I+N + R A V + ++ + +++ +++ + +V+
Sbjct: 15603 PLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLAENEYGIG 15662
Query: 1064 ------------DKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTME 1111
++P PP + + D +V+L W+ P+ G + + GY V+ K + +
Sbjct: 15663 LPAETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDK 15722
Query: 1112 WFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPN 1171
W T + T + LI G Y FRV +QN G SD P + P I
Sbjct: 15723 WATCAT-VKVTEATITGLIQGEEYSFRVSAQNEKGISD-------PRQLSVPVI------ 15768
Query: 1172 YKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFS 1231
A D P+F +V+AG + G P P ++W K+ + L + R S
Sbjct: 15769 --AKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAES 15826
Query: 1232 KQGVLTLEIRKPCPFDGGIYVCRATNLQGEA 1262
+ L I+ C D G YV + TN GEA
Sbjct: 15827 TENNSLLTIKDACREDVGHYVVKLTNSAGEA 15857
Score = 105 bits (263), Expect = 2e-22
Identities = 87/330 (26%), Positives = 141/330 (42%), Gaps = 40/330 (12%)
Query: 644 PPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPE 703
PP I L R DTI V AG + + ++G P P + W K N+ DA +
Sbjct: 9022 PPTIKLRLSVR-GDTIKVKAGEPVHIPADVTGLPMPKIEWSK-----NETVIEKPTDALQ 9075
Query: 704 DTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVN 763
T + V ++ ++ ++ A +ED+G YTVT N +G N
Sbjct: 9076 ITKEE------------------VSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRN 9117
Query: 764 LTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERK--KKKSYRWMRL 821
+ V+V D P P ++++ +SC + W+ P +GG I Y+++++ +K W +
Sbjct: 9118 VHVEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEV 9177
Query: 822 NFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQ-----PFMPIGPPSEPTHL 876
+ E + ++I YE RV AVN G+S + + P+ GPP +P L
Sbjct: 9178 TNTAV-EKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVL 9236
Query: 877 AVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSIL-----V 931
A + ++ + W PP G + GY +E EG W + + V
Sbjct: 9237 A---RTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVGLKGVEFNV 9293
Query: 932 KDLPTGARLLFRVRAHNMAGPGAPVTTTEP 961
L G + FR A N AG G P ++P
Sbjct: 9294 PRLLEGVKYQFRAMAINAAGIGPPSEPSDP 9323
Score = 105 bits (263), Expect = 2e-22
Identities = 85/322 (26%), Positives = 132/322 (40%), Gaps = 40/322 (12%)
Query: 657 DTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKK 716
D +++ +G LR+ + G P P V W K G
Sbjct: 21594 DGLIIKSGESLRIKALVQGRPVPRVTWFK---DG-------------------------- 21624
Query: 717 LLCETEGRVRVETTK---DRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPD 773
E E R+ +E T S+F V A ++ GVYTV KN G + + VKV D P
Sbjct: 21625 --VEIEKRMNMEITDVLGSTSLF-VRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPG 21681
Query: 774 APAAP-KISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHE 832
P + +N+ + T+ W+ P DG PI YI+E+++ W + D + S+
Sbjct: 21682 KVVGPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIE-DKCEAQSYT 21740
Query: 833 ARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPI--GPPSEPTHLAVEDVSDTTVSLKW 890
A ++I G Y+ RV AVN G+ RP + I P P +++ +++L W
Sbjct: 21741 AIKLINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTW 21800
Query: 891 RPPERVGAGGLDGYSVEYCPEGCSEWVAAL-QGLTEHTSILVKDLPTGARLLFRVRAHNM 949
PE G + Y +E + + WV + + T V L G F V A N
Sbjct: 21801 ARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVMAENA 21860
Query: 950 AGPGAPVTTTEPVTVQEILQRP 971
AG G + + +E + P
Sbjct: 21861 AGVGPASGISRLIKCREPVNPP 21882
Score = 105 bits (261), Expect = 4e-22
Identities = 130/548 (23%), Positives = 207/548 (37%), Gaps = 57/548 (10%)
Query: 738 VEGAEKEDEGVYTVTVKNPVGEDQ---VNLTVKVIDV---PDAPAAPKISNVGEDSCTVQ 791
V G ++ E + V+ +N G + + K D P P I + ++S T+
Sbjct: 17508 VTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLA 17567
Query: 792 WEPPAYDGGQPILGYILERKKKKSYRWMRLNFDL-IQELSHEARRMIEGVVYEMRVYAVN 850
W P YDGG ILGY++E K W + ++ E ++ E Y++RV A+N
Sbjct: 17568 WGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALN 17627
Query: 851 AIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCP 910
+G+ + P P + + + R V AGG + +
Sbjct: 17628 KVGLGEATSVPGTVKPEDKLEAP---------ELDLDSELRKGIVVRAGGSARIHIPFKG 17678
Query: 911 EGCSE--WVAALQGLTE---------HTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTT 959
E W T+ +T + + + + ++ N +G + T
Sbjct: 17679 RPTPEITWSREEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVT- 17737
Query: 960 EPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEV 1019
V V + P+ + +R+ V EP +I K + V +E A V
Sbjct: 17738 --VKVLDTPGPPQNLAVKEVRKDSAFLVWEPP--IIDGGAKVKNYVIDKRESTRKAYANV 17793
Query: 1020 SIRNSPTDTILFIRAARRVHSGTYQVTVRIEN-----MEDKATLVLQVVDKPSPPQDLRV 1074
S + S T + Y V EN + + ++ + PSPP + +
Sbjct: 17794 SSKCSKTS----FKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEPPSPPGKVTL 17849
Query: 1075 TDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNG 1134
TD + +L W+ P+ G + + GY V+ K T +W V E + + VV L G
Sbjct: 17850 TDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAES-KVCNAVVTGLSSGQE 17908
Query: 1135 YYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIA 1194
Y FRV + N G SD P + P I A D + PS P S+ A
Sbjct: 17909 YQFRVKAYNEKGKSD-------PRVLGVPVI--------AKDLTIQPSLKLPFNTYSIQA 17953
Query: 1195 GYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCR 1254
G + V G P+P ISW K+G L + R + L I++ D G Y
Sbjct: 17954 GEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVT 18013
Query: 1255 ATNLQGEA 1262
ATN G A
Sbjct: 18014 ATNSAGTA 18021
Score = 104 bits (260), Expect = 5e-22
Identities = 129/579 (22%), Positives = 235/579 (40%), Gaps = 81/579 (13%)
Query: 725 VRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPKISNVG 784
+ V K++S+ K ++G+ P+ ++ +T +V D+ D P A +G
Sbjct: 21148 IEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPITVKELIITPEV-DLSDIPGAQVTVRIG 21206
Query: 785 EDSCTVQWEPPAYDGGQPILGYI---LERKKKKSYRWMRLNFDLIQELSHEARRMIEGVV 841
+ V E P +P + ++ L K+ + R+ + + + + A++ G
Sbjct: 21207 HN---VHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKN-AKKEHGGKY 21262
Query: 842 YEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTH-LAVEDVSDTTVSLKWRPPERVGAGG 900
+ AV I + P + + +GPPS+P + +++ +V L W PE G G
Sbjct: 21263 TVILDNAVCRIAV----PIT--VITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGE 21316
Query: 901 LDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTE 960
+ YS+E + W + T+ V +L A FRVRA N G ++
Sbjct: 21317 ITCYSIEKRETSQTNWKMVCSSVAR-TTFKVPNLVKDAEYQFRVRAENRYG------VSQ 21369
Query: 961 PVTVQEILQRPRLQLPRHL-RQTIQKKVGEPVNLL--------------IPFQGKPRPQV 1005
P+ I+ + + ++P + I + ++L + K R +
Sbjct: 21370 PLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSI 21429
Query: 1006 TWTKEG-QPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENME--------DKA 1056
W K P++G E RA V YQ V EN K
Sbjct: 21430 LWQKVNTSPISGREY-------------RATGLVEGLDYQFRVYAENSAGLSSPSDPSKF 21476
Query: 1057 TLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEW---- 1112
TL + VD P P + VT + L+W PP G +++ GY+++K W
Sbjct: 21477 TLAVSPVDPPGTPDYIDVTRE---TITLKWNPPLRDGGSKIVGYSIEKRQGNE-RWVRCN 21532
Query: 1113 FTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNY 1172
FT + + T V L G+ Y FR+ ++N VG + + + + PP
Sbjct: 21533 FTDVSECQYT---VTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENV---PP-- 21584
Query: 1173 KALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSK 1232
++F P + L+ +S G + + V+G P P+++WFK+G+++ + +
Sbjct: 21585 -IVEFG--PEYFDGLIIKS---GESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDV 21638
Query: 1233 QGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVR 1271
G +L +R G+Y A N G A+ E +++V+
Sbjct: 21639 LGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQ 21677
Score = 103 bits (257), Expect = 1e-21
Identities = 124/529 (23%), Positives = 187/529 (35%), Gaps = 95/529 (17%)
Query: 772 PDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDL-IQELS 830
P PA PK+ + S ++ W PAYDGG PI+GY++E K+ S W+R N +Q+
Sbjct: 13217 PGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTR 13276
Query: 831 HEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTT----- 885
E ++E Y+ RVYAVN IG S PS P P D+ T
Sbjct: 13277 FEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAG 13336
Query: 886 ------VSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGAR 939
V +K RPP ++ W L + + +K T
Sbjct: 13337 VTMRLYVPVKGRPPPKI------------------TWSKPNVNLRDRIGLDIKS--TDFD 13376
Query: 940 LLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKV----GEPVNLLI 995
R N G + T E ++ TI KV G PVN+ +
Sbjct: 13377 TFLRCENVNKYDAGKYILTLENSCGKK-------------EYTIVVKVLDTPGPPVNVTV 13423
Query: 996 PFQGKPRPQVTWTKE----GQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIEN 1051
K VTW G P+ V R++ ++ V + + + R+ N
Sbjct: 13424 KEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAER------KSWSTVTTECSKTSFRVAN 13477
Query: 1052 MEDKATLVLQVVDK--------------------PSPPQDLRVTDAWGLNVALEWKPPQD 1091
+E+ + +V + P P DL+V + ++ WK P
Sbjct: 13478 LEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVVDLKVRSVSKSSCSIGWKKPHS 13537
Query: 1092 VGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRA 1151
G + + GY V ++ +W V++ + +L G Y FRV ++N G
Sbjct: 13538 DGGSRIIGYVVDFLTEEN-KWQRVMKSLSLQYSA-KDLTEGKEYTFRVSAENENG----E 13591
Query: 1152 ATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPK 1211
T E + R + LD P S L ++G P P
Sbjct: 13592 GTPSEITVVARDDVVAPD-----LDLKGLPDLCYLAKENS-----NFRLKIPIKGKPAPS 13641
Query: 1212 ISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQG 1260
+SW K L D R + S TL + D G Y N+ G
Sbjct: 13642 VSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAG 13690
Score = 102 bits (255), Expect = 2e-21
Identities = 114/505 (22%), Positives = 205/505 (40%), Gaps = 45/505 (8%)
Query: 704 DTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVN 763
D G E + L T+ VRV + + G + E + V N GE + +
Sbjct: 7638 DGGAKIESYVIEMLKTGTDEWVRVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPS 7697
Query: 764 ------LTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYR 817
L + + P P ++ N+ +++ ++W P DGG PI YI+E++ +
Sbjct: 7698 EPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKG 7757
Query: 818 WMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMP---IGPPSEPT 874
W ++ +++ + EG +Y RV A NAIG S + + P P
Sbjct: 7758 WQTVD-TTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPY 7816
Query: 875 HLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDL 934
LAV DV+ V LKW PP+ G + Y +E + WV A + + V D+
Sbjct: 7817 ALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDV 7876
Query: 935 PTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLL 994
G + F+VRA N AG G P TE +++++ P L H+ +K + +
Sbjct: 7877 IEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIA--IAWK 7934
Query: 995 IPFQGKPRPQVTWTKEGQPLAGEE-VSIRNSPTDTILFIRAARRVHSGTYQVTVRIEN-- 1051
P + P + + E P+ E+ + + + P + F V Y + VR N
Sbjct: 7935 PPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAI 7994
Query: 1052 -MEDKATLVLQVVDKPS--------PPQDLRVTDAWGLNVALEWKP-PQDVGNTELWGYT 1101
+ + + + VV K D+ V + L++ + ++ P + G
Sbjct: 7995 GVSEPSEISENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKE 8054
Query: 1102 VQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIP 1161
V+ +D+ TM+ + H VP+ + + + + +N +G S A+ + + +P
Sbjct: 8055 VKASDRLTMK-----NDHISAHLEVPKSVRADAGIYTITLENKLG-SATASINVKVIGLP 8108
Query: 1162 RP--------------GITYEPPNY 1172
P +T+EPP +
Sbjct: 8109 GPCKDIKASDITKSSCKLTWEPPEF 8133
Score = 102 bits (255), Expect = 2e-21
Identities = 86/332 (25%), Positives = 131/332 (39%), Gaps = 39/332 (11%)
Query: 644 PPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPE 703
PP +HLD D + + G L SG P P V W K
Sbjct: 10445 PPTLHLD----FRDKLTIRVGEAFALTGRYSGKPKPKVSWFK------------------ 10482
Query: 704 DTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVN 763
D D E + R ++TT A++ D G Y V V+N G +
Sbjct: 10483 DEADVLE-----------DDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGF 10531
Query: 764 LTVKVIDVPDAPAAP-KISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLN 822
V V+D P P P V +D + W+PP DGG I YI+E+K+ WM +
Sbjct: 10532 CQVNVVDRPGPPVGPVSFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPVT 10591
Query: 823 FDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRP--SPASQPFMPIGPPSEPTHLAVED 880
+ + + +++EG Y R++A N G+S P S + + P P V +
Sbjct: 10592 -SASAKTTCKVSKLLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTE 10650
Query: 881 VSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQG-LTEHTSILVKDLPTGAR 939
V+ + + W P G + Y +E W + + +T V DL G +
Sbjct: 10651 VTKDSALVTWNKPHD-GGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQ 10709
Query: 940 LLFRVRAHNMAGPGAPVTTTEPVTVQEILQRP 971
FRV A N G G P ++PV ++ + +P
Sbjct: 10710 YEFRVSAENEIGIGDPSPPSKPVFAKDPIAKP 10741
Score = 102 bits (253), Expect = 3e-21
Identities = 150/635 (23%), Positives = 235/635 (37%), Gaps = 110/635 (17%)
Query: 680 TVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVE 739
TV+W +RP D D DKK L +V ET +D V
Sbjct: 20711 TVVW-----------SRPIADGGSDISGYFLEKRDKKSLGWF--KVLKETIRDTRQ-KVT 20756
Query: 740 GAEKEDEGVYTVTVKNPVGE------DQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWE 793
G + + Y V N G+ + ID P PA +I++ + S T+ W
Sbjct: 20757 GLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSITLGWS 20816
Query: 794 PPAYDGGQPILGYILERKKKKSYRWMRLNFD-LIQELSHEARRMIEGVVYEMRVYAVNAI 852
P YDGG + GY++E ++ + W ++ ++ + + GV Y RV AVN
Sbjct: 20817 KPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCA 20876
Query: 853 GMSRPSPASQPFMP---IGPPSEPTHLAV---------EDVSDTTVSLKWRPPERV---- 896
G P ++P + P +A+ EDV + K RPP V
Sbjct: 20877 GQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAGEDVQ-VLIPFKGRPPPTVTWRK 20935
Query: 897 ---GAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSIL----VKDLPTGARLLFRVRAHNM 949
G YS+E T+ +S+L V TG +L
Sbjct: 20936 DEKNLGSDARYSIEN---------------TDSSSLLTIPQVTRNDTGKYILTIEN---- 20976
Query: 950 AGPGAPVTTTEPVTVQEILQRP----RLQLPRHLRQTIQKKVGEP--------VNLLIPF 997
G G P ++T V ++L P +LQ+ R T+ P +N +I
Sbjct: 20977 -GVGEPKSSTVSV---KVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVI-- 21030
Query: 998 QGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKAT 1057
+ + + TW+ + + + T F R G + + T
Sbjct: 21031 EKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPC--------ETT 21082
Query: 1058 LVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLE 1117
++ + P+P +DL + D+ +V L W P G + + Y V++ K W +
Sbjct: 21083 EPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERKGKGEQTW-SHAG 21141
Query: 1118 HYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDF 1177
+ V +L + FRVF++N G SD T P+ + IT E +D
Sbjct: 21142 ISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSD--PVTIGPITVKELIITPE------VDL 21193
Query: 1178 SEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLT 1237
S+ P +V G+ L +G PKP ISW K+GL L E R + +T
Sbjct: 21194 SDIPG-----AQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKIT 21248
Query: 1238 LEIRKPCPFDGGIYVCRATNLQGEARCECRLEVRV 1272
L I+ GG Y N CR+ V +
Sbjct: 21249 LSIKNAKKEHGGKYTVILDN------AVCRIAVPI 21277
Score = 101 bits (252), Expect = 4e-21
Identities = 134/560 (23%), Positives = 208/560 (37%), Gaps = 74/560 (13%)
Query: 736 FTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPP 795
+TV+G ++ D Y V+ N VG+ + + K I D A P + D T++
Sbjct: 10404 YTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHLDFRDKLTIRV--- 10460
Query: 796 AYDGGQPILGYILERKKKKSYRWMRLNFDLIQE-LSH-------------EARRMIEG-- 839
G L K K W + D++++ +H +A+R G
Sbjct: 10461 ---GEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKY 10517
Query: 840 -VVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGA 898
VV E + G + + +P P+GP S ++V+ + + W+PP G
Sbjct: 10518 CVVVENSTGSRK--GFCQVNVVDRPGPPVGPVS------FDEVTKDYMVISWKPPLDDGG 10569
Query: 899 GGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTT 958
+ Y +E G W+ + T+ V L G +FR+ A N+ G
Sbjct: 10570 SKITNYIIEKKEVGKDVWMPVTSASAK-TTCKVSKLLEGKDYIFRIHAENLYG------I 10622
Query: 959 TEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLI---PFQG-KPRPQVTWTKEGQPL 1014
++P+ + + R ++P Q I +V + L+ P G KP K + +
Sbjct: 10623 SDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHDGGKPITNYILEKR-ETM 10681
Query: 1015 AGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENM--------EDKATLVLQVVDKP 1066
+ + P R + Y+ V EN K + KP
Sbjct: 10682 SKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKP 10741
Query: 1067 SPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVL---EHYRRTH 1123
SPP + D +V L W+PP+ G +++ GY V+ EW E T
Sbjct: 10742 SPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPETK 10801
Query: 1124 CVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGIT---YEPPNYKALDFSEA 1180
V L G Y FRV + N G SD P +P P + EPP LD + A
Sbjct: 10802 YKVTGLRDGQTYKFRVLAVNAAGESD-------PAHVPEPVLVKDRLEPPEL-ILDANMA 10853
Query: 1181 PSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEI 1240
+ + G T L ++G P PK++W K D AR + LEI
Sbjct: 10854 RE-------QHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGS--KLEI 10904
Query: 1241 RKPCPFDGGIYVCRATNLQG 1260
R DGGIY N G
Sbjct: 10905 RNAAHEDGGIYSLTVENPAG 10924
Score = 101 bits (251), Expect = 5e-21
Identities = 79/286 (27%), Positives = 133/286 (46%), Gaps = 11/286 (3%)
Query: 359 EKKSTAFQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAK 418
E+ F K LE V KG + L+ EL + + +V W K+G+ + + + IG
Sbjct: 4836 EELPVRFVKTLEEEVTVVKGQPLYLSCEL-NKERDVVWRKDGKIVVEKPGRIVPGVIGLM 4894
Query: 419 RTLTISQCSLADDAAYQCVVGGE---KCSTELFVKEPPVL---ITRPLEDQLVMVGQRVE 472
R LTI+ D Y V +CS+ VK V+ + +P+ DQ V
Sbjct: 4895 RALTINDADDTDAGTYTVTVENANNLECSS--CVKVVEVIRDWLVKPIRDQHVKPKGTAI 4952
Query: 473 FECEVSEEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGG 532
F C+++++ +KW K E+ E K +DG +L I AM ED YA+ G
Sbjct: 4953 FACDIAKDTPNIKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEGK 5012
Query: 533 QALAELIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKV 592
+ A+L + E+++E+ + I D+ + K+ A F E+S+ ++ G W G+ L P ++
Sbjct: 5013 RYPAKLTLGEREVELLKPIEDVTIYEKESASFDAEISEADIPGQWKLKGELLRPSPTCEI 5072
Query: 593 SHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDF 638
G LT+ V D+A + + +A L E+++DF
Sbjct: 5073 KAEGGKRFLTLHKV-KLDQAG-EVLYQALNAITTAILTVKEIELDF 5116
Score = 101 bits (251), Expect = 5e-21
Identities = 142/653 (21%), Positives = 242/653 (37%), Gaps = 78/653 (11%)
Query: 661 VVAGNKLRLDVPISGDP-----------APTVIWQKAITQGNKAPARPAPDAPEDTGDSD 709
++A NK + P+ +P AP ++T+ + P+ + +
Sbjct: 9919 IMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTG 9978
Query: 710 EWVFDKKLLCETEGRVRVETTKDRSI---FTVEGAEKEDEGVYTVTVKNPVGEDQVNL-- 764
W+ K + RV + K ++ + V G + + + V N G +L
Sbjct: 9979 YWLEMKDTTSKRWKRVNRDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPS 10038
Query: 765 ---TVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRL 821
T + P P PK+++ + S ++W PP DGG + GYI+E K++ W +
Sbjct: 10039 DPATARDPIAPPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKG 10098
Query: 822 NFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDV 881
++ + EG Y+ RV AVN G+ P + P V
Sbjct: 10099 KDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASV 10158
Query: 882 SDTTVSLKWRPPERVGAGGLDGYS--VEYCPEGCSEW---------VAALQGLTEHTSIL 930
D V V AGG+ V P W A ++ +S++
Sbjct: 10159 RDRIV---------VHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMV 10209
Query: 931 VKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKV--- 987
+K+ + ++ + A N AG + + V + P L +L K
Sbjct: 10210 IKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLA--HNLTNESCKLTWFS 10267
Query: 988 -----GEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGT 1042
G P+ + + + + WT + + +++ F R A G
Sbjct: 10268 PEDDGGSPITNYV-IEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGM 10326
Query: 1043 YQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTV 1102
+E E A ++ + + P P+DL V + V L W PP+ G +E+ Y +
Sbjct: 10327 GPF---VETSE--ALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVL 10381
Query: 1103 QKADKKTMEWFTVL-EHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIP 1161
+ T ++ V ++ V L G+ Y +RV + N+VG +P F
Sbjct: 10382 ESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQG-------KPSFCT 10434
Query: 1162 RPGITYE----PPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKN 1217
+P IT + PP LDF + ++ G L G PKPK+SWFK+
Sbjct: 10435 KP-ITCKDELAPPTLH-LDFRD---------KLTIRVGEAFALTGRYSGKPKPKVSWFKD 10483
Query: 1218 GLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
D+ ED R + + L LE K D G Y N G + C++ V
Sbjct: 10484 EADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNV 10536
Score = 100 bits (250), Expect = 7e-21
Identities = 118/495 (23%), Positives = 197/495 (39%), Gaps = 46/495 (9%)
Query: 736 FTVEGAEKEDEGVYTVTVKNPVG---EDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQW 792
F G E+ E + V+ +N VG +V+ D D P P+ V +S T+QW
Sbjct: 16028 FKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAIIVTRNSVTLQW 16087
Query: 793 EPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAI 852
+ P YDGG I GYI+E+K+ RWM+ +F I + E ++E YE RV A NA
Sbjct: 16088 KKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVIARNAA 16147
Query: 853 GMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEG 912
G+ S + +P ++++ T+ + +V A D Y P
Sbjct: 16148 GVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDA---DIYGK---PIP 16201
Query: 913 CSEWVAALQGLTEHTSILVKDLPTGARL----LFRVRAHNMAGPGAPVTTTEPVTVQ-EI 967
+W+ Q L+ + +K L RV + N V VTV ++
Sbjct: 16202 TIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKV 16261
Query: 968 LQRPRLQLPRHLRQTIQKKVGEPVNLL--IPFQGKPRPQVTWTKEGQPLAGEEVSIRNSP 1025
L RP P I E L P Q + + E + + ++ ++
Sbjct: 16262 LDRPG---PPEGPVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVDAN 16318
Query: 1026 TDTILFIRAARRVHSGTYQVTVRIEN-------MEDKATLVLQVVDKPSPPQDLRVTDAW 1078
T L + + + Y + N +E + + P P+ VT
Sbjct: 16319 VQT-LSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVT 16377
Query: 1079 GLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYR---RTHCVVPELIIGNGY 1135
++ + W+ P G +E+ GY ++K DK+ + W H R V LI + Y
Sbjct: 16378 KDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRC--HKRLIGELRLRVTGLIENHDY 16435
Query: 1136 YFRVFSQNMVGFSDRAATTK-----EPVFIPRPGITYEPPNYKALDFSEAP---SFTQPL 1187
FRV ++N G S+ + + +P++ P P P N K +D + + S+++P+
Sbjct: 16436 EFRVSAENAAGLSEPSPPSAYQKACDPIYKPGP-----PNNPKVIDITRSSVFLSWSKPI 16490
Query: 1188 VNRSV-IAGYTAMLC 1201
+ I GY C
Sbjct: 16491 YDGGCEIQGYIVEKC 16505
Score = 100 bits (248), Expect = 1e-20
Identities = 107/487 (21%), Positives = 186/487 (38%), Gaps = 42/487 (8%)
Query: 800 GQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSP 859
G+P+ L R MR N ++ E + + E V + Y + A S +
Sbjct: 20130 GKPLPKVTLSRDGVPLKATMRFNTEITAE--NLTINLKESVTADAGRYEITAANSSGTTK 20187
Query: 860 ASQPFMPIGPPSEPTH-LAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVA 918
A + + P PT + + D+++ +V+LKW PP+ G + Y + + W
Sbjct: 20188 AFINIVVLDRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTE 20247
Query: 919 ALQGLTEHTSILVKDLPTGARLLFRVRAHNMAG-----PGAPVTTTEPVTVQEILQRPRL 973
+ T + V L TG FR++A N G A VT P T P
Sbjct: 20248 -VSATVARTMMKVMKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTP-- 20304
Query: 974 QLPRHLRQTIQKKVGEPVN------LLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTD 1027
+ R++I EPV+ + + K R + W K ++ IR +
Sbjct: 20305 WVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQK------ANKLVIRTTHFK 20358
Query: 1028 TILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWK 1087
+ I A Y + + +D PP+++R+TD +V+L W+
Sbjct: 20359 -VTTISAGLIYEFRVYAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQ 20417
Query: 1088 PPQDVGNTELWGYTVQKADKKTMEWFTV-LEHYRRTHCVVPELIIGNGYYFRVFSQNMVG 1146
P G +++ GY V++ D W + T ++ L + Y FRVF++N VG
Sbjct: 20418 QPAFDGGSKITGYIVERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVG 20477
Query: 1147 FSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVI---AGYTAMLCCA 1203
+ P+ +D P PL V+ AG + L
Sbjct: 20478 SISNPSEVVGPI--------------TCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAG 20523
Query: 1204 VRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEAR 1263
+ G P P I W+K+ +L +A + + + ++ I+ + G Y + N G A
Sbjct: 20524 ISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRNAMGSAS 20583
Query: 1264 CECRLEV 1270
R+++
Sbjct: 20584 ATIRVQI 20590
Score = 99.4 bits (246), Expect = 2e-20
Identities = 77/249 (30%), Positives = 111/249 (44%), Gaps = 13/249 (5%)
Query: 391 DAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCV---VGGEKCSTEL 447
D E +W KNG +I+ S Y + L I + D A+ + GE S
Sbjct: 2060 DPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAF 2119
Query: 448 FVKEPPVLITRPLEDQLVMVGQR---VEFECEVSEEGAQVKWLKDGVELTREETFKYRFK 504
+ + LIT E Q V+ ++ FECE SE +VKW KDG+E+ E KYR
Sbjct: 2120 LLVQAKQLITFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEV--HEGDKYRMH 2177
Query: 505 KDGQRHHLIINEAMLEDAGHYALC---TSGGQALAELIVQEKKLEVYQSIADLMVGAKDQ 561
D + H L I DA Y+ + A+LIV+ +E + + D+ V
Sbjct: 2178 SDRKVHFLSILTIDTSDAEDYSCVLVEDENVKTTAKLIVEGAVVEFVKELQDIEVPESYS 2237
Query: 562 AVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEG- 620
+C VS EN+ G W N EL + + ++ LT+ DVT D+ +YSFV +G
Sbjct: 2238 GELECIVSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGK 2297
Query: 621 -FACNLSAK 628
C L K
Sbjct: 2298 KTTCKLKMK 2306
Score = 99.0 bits (245), Expect = 3e-20
Identities = 116/522 (22%), Positives = 200/522 (38%), Gaps = 83/522 (15%)
Query: 772 PDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDL-IQELS 830
P P+ PK+++ S ++ W P YDGG P+ GY++E K+ + W +Q
Sbjct: 18631 PGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQ 18690
Query: 831 HEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMP---IGPP-----SEPTHLAVEDVS 882
++ E Y R+ A+N+ G+ P+ + I PP ++ + V S
Sbjct: 18691 FTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRAS 18750
Query: 883 DTT---VSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGAR 939
T V++K RP V +G + A ++ + T +++ ++
Sbjct: 18751 ATLRLFVTIKGRPEPEVKWEKAEGILTDR---------AQIEVTSSFTMLVIDNVTRFDS 18801
Query: 940 LLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQG 999
+ + N +G + T V V+ +L P PVNL I
Sbjct: 18802 GRYNLTLENNSG-----SKTAFVNVR-VLDSP----------------SAPVNLTIREVK 18839
Query: 1000 KPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAA-RRVHSGTYQVTVRIENMED---- 1054
K ++W PL I N + R A + + + T RIEN+++
Sbjct: 18840 KDSVTLSWEP---PLIDGGAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSY 18896
Query: 1055 ----------------KATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELW 1098
+ T ++V + P PP + + D ++W+ P+ G +++
Sbjct: 18897 YFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKIT 18956
Query: 1099 GYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPV 1158
GY V+ K + +W T + + + L G Y FRV + N G SD P
Sbjct: 18957 GYVVEMQTKGSEKWSTCTQ-VKTLEATISGLTAGEEYVFRVAAVNEKGRSD-------PR 19008
Query: 1159 FIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNG 1218
+ P I A D PS P +V A + +G P+ ++W K+G
Sbjct: 19009 QLGVPVI--------ARDIEIKPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDG 19060
Query: 1219 LDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQG 1260
L E R + S + V +L I++ D G Y +N G
Sbjct: 19061 QTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAG 19102
Score = 99.0 bits (245), Expect = 3e-20
Identities = 115/467 (24%), Positives = 176/467 (37%), Gaps = 65/467 (13%)
Query: 824 DLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSD 883
DL L +A R+ G YE+++ NA+G + + Q GPP P + + V+
Sbjct: 20554 DLASILIKDADRLNSGC-YELKLR--NAMGSASATIRVQILDKPGPPGGP--IEFKTVTA 20608
Query: 884 TTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFR 943
++L WRPP G + Y VE W + L E I + G +FR
Sbjct: 20609 EKITLLWRPPADDGGAKITHYIVEKRETSRVVWSMVSEHL-EECIITTTKIIKGNEYIFR 20667
Query: 944 VRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRP 1003
VRA N G G P+ + V + +P + T K
Sbjct: 20668 VRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKIT-----------------KNSM 20710
Query: 1004 QVTWTKE----GQPLAGEEVSIRNSPT--------DTILFIR--AARRVHSGTYQVTVRI 1049
V W++ G ++G + R+ + +TI R + YQ V
Sbjct: 20711 TVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCA 20770
Query: 1050 ENMEDKATL--------VLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYT 1101
N + +D P PP +R+ D+ ++ L W P G + + GY
Sbjct: 20771 VNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYV 20830
Query: 1102 VQKADKKTMEWFTVLE--HYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVF 1159
V+ + EW TV R T VV L G YYFRV + N G EP+
Sbjct: 20831 VEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQG-------EPIE 20883
Query: 1160 IPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVI---AGYTAMLCCAVRGSPKPKISWFK 1216
+ P +A D EAP + R+ + AG + +G P P ++W K
Sbjct: 20884 MNEP--------VQAKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRK 20935
Query: 1217 NGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEAR 1263
+ +LG DAR+ + + L I + D G Y+ N GE +
Sbjct: 20936 DEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPK 20982
Score = 98.6 bits (244), Expect = 3e-20
Identities = 116/522 (22%), Positives = 197/522 (37%), Gaps = 81/522 (15%)
Query: 772 PDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDL-IQELS 830
P P PK+ ++ S + W P YDGG I GYI+E+ W I + +
Sbjct: 16466 PGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTN 16525
Query: 831 HEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PIGPPSEPTHLAVEDVSDTT-- 885
E +++E Y R+ A+N G+ + P + + P L + + +
Sbjct: 16526 IEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAG 16585
Query: 886 ------VSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGAR 939
V +K RP V G +DG + A + + TS+++ ++
Sbjct: 16586 GSLRLFVPIKGRPTPEVKWGKVDGEIRD---------AAIIDVTSSFTSLVLDNVNRYDS 16636
Query: 940 LLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQG 999
+ + N +G T + VTV+ +L P PVNL +
Sbjct: 16637 GKYTLTLENSSG-----TKSAFVTVR-VLDTP----------------SPPVNLKVTEIT 16674
Query: 1000 KPRPQVTWTKE----GQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVT--------- 1046
K +TW G + V R + + + H ++++
Sbjct: 16675 KDSVSITWEPPLLDGGSKIKNYIVEKREATRKS--YAAVVTNCHKNSWKIDQLQEGCSYY 16732
Query: 1047 --VRIEN-----MEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWG 1099
V EN + + ++V + P PP + V D +V+L W P+ G +++
Sbjct: 16733 FRVTAENEYGIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQ 16792
Query: 1100 YTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVF 1159
Y V+ K + +W + + V+ L G Y FRV + N G SD + V
Sbjct: 16793 YIVEMQAKHSEKW-SECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLA---VP 16848
Query: 1160 IPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGL 1219
I + EP P+F+ + SV G + + G PKP I+W K+GL
Sbjct: 16849 IVAKDLVIEP--------DVKPAFS----SYSVQVGQDLKIEVPISGRPKPTITWTKDGL 16896
Query: 1220 DLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGE 1261
L + R + + TL I++ DGG Y N+ G+
Sbjct: 16897 PLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQ 16938
Score = 98.6 bits (244), Expect = 3e-20
Identities = 125/521 (23%), Positives = 208/521 (39%), Gaps = 94/521 (18%)
Query: 736 FTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVI---DVPDAPAAPKISNVGEDSCTVQW 792
F + E+ E + V +N VG + + + D D P P+ V + T+QW
Sbjct: 17110 FKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPPGTPEPIMVKRNEITLQW 17169
Query: 793 EPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAI 852
P YDGG I GYI+E++ RWM+ +F + E + E YE RV A NA
Sbjct: 17170 TKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAA 17229
Query: 853 G-MSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSL--KWRPPERVGAGGLDGYSVEYC 909
G +S+PS ++ P A ++V +S+ K+R V AG + + +E
Sbjct: 17230 GAISKPSDSTGPI-----------TAKDEVELPRISMDPKFRDTIVVNAG--ETFRLEAD 17276
Query: 910 PEG----CSEWVAALQGLTEHTSILVKDLPTGARLLFR-----------VRAHNMAGPGA 954
G EW+ + + E +K+ A L+ + +RA N+AG
Sbjct: 17277 VHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAG--- 17333
Query: 955 PVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVN-LLIPFQGKPRPQVTWTKEGQP 1013
+ + PV V ++L RP G P + + + +TW+ Q
Sbjct: 17334 --SKSFPVNV-KVLDRP----------------GPPEGPVQVTGVTSEKCSLTWSPPLQD 17374
Query: 1014 LAGEEVS---IRNSPTDTILFIRAARRVHSGTYQVTVRIEN------------------M 1052
G ++S + T + + A V + + +VT +E +
Sbjct: 17375 -GGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPL 17433
Query: 1053 EDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEW 1112
E L+ P PP+ L VT+ ++ + W P G +E+ GY V+K D+ + W
Sbjct: 17434 ESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRW 17493
Query: 1113 FTV-LEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTK-----EPVFIPRPGIT 1166
V L + Y FRV ++N G + + T +PVF P P
Sbjct: 17494 IKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGP--- 17550
Query: 1167 YEPPNYKALDFSE---APSFTQPLVN-RSVIAGYTAMLCCA 1203
P N +D ++ ++ +P+ + S I GY +C A
Sbjct: 17551 --PTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEICKA 17589
Score = 97.4 bits (241), Expect = 8e-20
Identities = 105/411 (25%), Positives = 162/411 (39%), Gaps = 57/411 (13%)
Query: 876 LAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLP 935
L V V+ +L W P+ G + Y VE WV ++G S +V L
Sbjct: 22775 LTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLNWVI-VEGECPTLSYVVTRLI 22833
Query: 936 TGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLI 995
+FRVRA N GPG PV + EP+ + P I ++VG
Sbjct: 22834 KNNEYIFRVRAVNKYGPGVPVES-EPIVARNSFTIPS-------PPGIPEEVGT------ 22879
Query: 996 PFQGKPRPQVTWTKE----GQPLAGEEVSIRNSPT--------DTILF---IRAARRVHS 1040
GK + WTK G ++ V R + D +++ ++ +
Sbjct: 22880 ---GKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEG 22936
Query: 1041 GTYQVTVRIENME-----DKATLVLQVVDK---PSPPQDLRVTDAWGLNVALEWKPPQDV 1092
YQ V N +A+ + + P PP RV D +++L W P
Sbjct: 22937 CDYQFRVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYD 22996
Query: 1093 GNTELWGYTVQKADKKTMEWFTVLEH--YRRTHCVVPELIIGNGYYFRVFSQNMVGFSDR 1150
G T++ GY ++ +K T +W+ V + R T VP+L +G Y FRV + N+ G S+
Sbjct: 22997 GGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEY 23056
Query: 1151 AATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKP 1210
+ + E + R I D A + + R AG + L +V G P P
Sbjct: 23057 SESIAEIEPVERIEIP---------DLELADDLKKTVTIR---AGASLRLMVSVSGRPPP 23104
Query: 1211 KISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGE 1261
I+W K G+DL A +L ++ K +D G Y A N G+
Sbjct: 23105 VITWSKQGIDLASRAIIDTTESYSLLIVD--KVNRYDAGKYTIEAENQSGK 23153
Score = 95.1 bits (235), Expect = 4e-19
Identities = 68/224 (30%), Positives = 97/224 (43%), Gaps = 4/224 (1%)
Query: 391 DAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCSTELFVK 450
+A V W K G +I S K+ + G K L I+ D+ Y V G+K S LFV
Sbjct: 5140 EANVIWSK-GPDIIKSSDKFDIIADGKKHILVINDSQFDDEGVYTAEVEGKKTSARLFVT 5198
Query: 451 EPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKKDGQRH 510
+ PLEDQ V G+ F CE+S E V W K+ +L T +G+ H
Sbjct: 5199 GIRLKFMSPLEDQTVKEGETATFVCELSHEKMHVVWFKNDAKLHTSRTVL--ISSEGKTH 5256
Query: 511 HLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSD 570
L + E L+D + A+L V E + D KD+ KCEVS
Sbjct: 5257 KLEMKEVTLDDISQIKAQVKELSSTAQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVS- 5315
Query: 571 ENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADY 614
++V W K+G+E+VP + + G L I D+ +Y
Sbjct: 5316 KDVPVKWFKDGEEIVPSPKYSIKADGLRRILKIKKADLKDKGEY 5359
Score = 94.4 bits (233), Expect = 6e-19
Identities = 97/413 (23%), Positives = 161/413 (38%), Gaps = 53/413 (12%)
Query: 870 PSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSI 929
P P + +++VS ++++ W PPE G + Y VE + W Q + TSI
Sbjct: 19116 PGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQAVAR-TSI 19174
Query: 930 LVKDLPTGARLLFRVRAHNMAGPGA-----------PVTTTEPVTVQEILQRPRLQLPRH 978
+ L TG+ FRV A N G + P + P +++ + +
Sbjct: 19175 KIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTM--- 19231
Query: 979 LRQTIQKKVGEPVNLLIPF--QGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAAR 1036
T Q V + + +I + + K R + W+K + L + ++ S D L
Sbjct: 19232 -LVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANKILIAD-TQMKVSGLDEGLM----- 19284
Query: 1037 RVHSGTYQVTVRIENME-----DKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQD 1091
Y+ V EN+ K+ + D PP VT+ +V+L+W P
Sbjct: 19285 ------YEYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQPEVTNITRKSVSLKWSKPHY 19338
Query: 1092 VGNTELWGYTVQKADKKTMEWFTV-LEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDR 1150
G ++ GY V++ + W + + T+ V EL Y FRVF++N
Sbjct: 19339 DGGAKITGYIVERRELPDGRWLKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSE 19398
Query: 1151 AATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVI---AGYTAMLCCAVRGS 1207
+ + P+ + D E P + R VI AG + + G
Sbjct: 19399 PSESTGPIIVK--------------DDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGR 19444
Query: 1208 PKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQG 1260
P P ISW K+G+++ E AR + S L ++ D G YV N+ G
Sbjct: 19445 PLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAG 19497
Score = 93.2 bits (230), Expect = 1e-18
Identities = 98/428 (22%), Positives = 164/428 (38%), Gaps = 61/428 (14%)
Query: 868 GPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHT 927
GPP+ P + ++V+ +++L W PP+ G ++ Y VE + W + T
Sbjct: 15870 GPPTGPVKM--DEVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTW-QIVSATVART 15926
Query: 928 SILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQ----LPRHLRQTI 983
+I L TG FR+ A N G + + EP Q + P + R ++
Sbjct: 15927 TIKACRLKTGCEYQFRIAAENRYGKSTYLNS-EPTVAQYPFKVPGPPGTPVVTLSSRDSM 15985
Query: 984 QKKVGEPVN------LLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARR 1037
+ + EP++ + + K R + W K + +P F +
Sbjct: 15986 EVQWNEPISDGGSRVIGYHLERKERNSILWVK-----------LNKTPIPQTKF-KTTGL 16033
Query: 1038 VHSGTYQVTVRIENME--------DKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPP 1089
Y+ V EN+ + + D P P+ + VT +V L+WK P
Sbjct: 16034 EEGVEYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAIIVTRN---SVTLQWKKP 16090
Query: 1090 QDVGNTELWGYTVQKADKKTMEWFTV-LEHYRRTHCVVPELIIGNGYYFRVFSQNMVGF- 1147
G +++ GY V+K + W + TH V L+ + Y FRV ++N G
Sbjct: 16091 TYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVF 16150
Query: 1148 -----SDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCC 1202
S A T ++ V PR S P + +V V AG + +
Sbjct: 16151 SEPSESTGAITARDEVDPPR--------------ISMDPKYKDTIV---VHAGESFKVDA 16193
Query: 1203 AVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEA 1262
+ G P P I W K +L AR + S +L ++ D G Y+ +A N+ GE
Sbjct: 16194 DIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGER 16253
Query: 1263 RCECRLEV 1270
++V
Sbjct: 16254 SVTVNVKV 16261
Score = 92.4 bits (228), Expect = 2e-18
Identities = 114/418 (27%), Positives = 156/418 (37%), Gaps = 43/418 (10%)
Query: 870 PSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGC--SEWVAALQGLTEHT 927
P P + ED+ T+V KW PP G + Y++E + SEW+ L H
Sbjct: 8430 PGPPINFVFEDIRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWIVVTSTL-RHC 8488
Query: 928 SILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKV 987
V L G LFRVRA N GPG P + +P+ ++ P K +
Sbjct: 8489 KYSVTKLIEGKEYLFRVRAENRFGPGPPCVS-KPLVAKDPFGPP---------DAPDKPI 8538
Query: 988 GEPV--NLLIPFQGKPR----PQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSG 1041
E V N ++ +P+ P + + E + + S N L +
Sbjct: 8539 VEDVTSNSMLVKWNEPKDNGSPILGYWLEKREVNSTHWSRVNKSLLNALKANVDGLLEGL 8598
Query: 1042 TYQVTVRIENMEDKATL--------VLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVG 1093
TY V EN + P PP RVTD + LEW+PP G
Sbjct: 8599 TYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIP-RVTDTSSTTIELEWEPPAFNG 8657
Query: 1094 NTELWGYTVQKADKKTMEWFTVLEHYRRTH-CVVPELIIGNGYYFRVFSQNMVGFSDRAA 1152
E+ GY V K T EW E + V E+ G Y RV + N G
Sbjct: 8658 GGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGEGPPGE 8717
Query: 1153 TTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKI 1212
T +PV + P EPP + LD S ++AG T + V G P P
Sbjct: 8718 T--QPVTVAEP---QEPPAVE-LDVSVKGGI-------QIMAGKTLRIPAVVTGRPVPTK 8764
Query: 1213 SWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
W K +L +D R + + L I+ D G YV ATN G R+EV
Sbjct: 8765 VWTKEEGELDKD-RVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEV 8821
Score = 92.4 bits (228), Expect = 2e-18
Identities = 101/405 (24%), Positives = 158/405 (39%), Gaps = 35/405 (8%)
Query: 867 IGPPSEPTH-LAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTE 925
+G P PT + ++V+ ++LKW PP+ G + Y +E ++WV + +
Sbjct: 13701 VGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCASAV-Q 13759
Query: 926 HTSILVKDLPTGARLLFRVRAHNMAGPGA-----PVTTTEPVTVQEILQRPRLQLPRH-- 978
T+ V L G FRV A N G G P+ P V + P + RH
Sbjct: 13760 KTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNIVDVRHDS 13819
Query: 979 --LRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQ-PLAGEEVSIRNSPTDTILFIRAA 1035
L T KK G + K R + W + + P+ + + R
Sbjct: 13820 VSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLEYEFRVM 13879
Query: 1036 RRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNT 1095
+G V ++ + + L +D P P+ + +T +V L W P+ G
Sbjct: 13880 AINLAG-----VGKPSLPSEPVVALDPIDPPGKPEVINITRN---SVTLIWTEPKYDGGH 13931
Query: 1096 ELWGYTVQKADKKTMEWFTVLEHYRRTHCV--VPELIIGNGYYFRVFSQNMVGFSDRAAT 1153
+L GY V+K D + W H C V +L+ G Y FR+ ++N G +
Sbjct: 13932 KLTGYIVEKRDLPSKSWMKA-NHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSE 13990
Query: 1154 TKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAML-CCAVRGSPKPKI 1212
+ E + YE P LD P+ L ++ AG T +L ++ G P PK
Sbjct: 13991 STETIICKDE---YEAPTI-VLD----PTIKDGL---TIKAGDTIVLNAISILGKPLPKS 14039
Query: 1213 SWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATN 1257
SW K G D+ ++ S L I+ D G Y ATN
Sbjct: 14040 SWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATN 14084
Score = 91.3 bits (225), Expect = 5e-18
Identities = 65/244 (26%), Positives = 113/244 (46%), Gaps = 6/244 (2%)
Query: 374 QVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAA 433
+V +G ++L V+++ E W+K+GQE+Q S +I L I + D
Sbjct: 2320 KVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHIVID-KQSHMLLIEDMTKEDAGN 2378
Query: 434 YQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVS-EEGAQVKWLKDGVE 492
Y + ST V V + PL+D V+ G + EC+VS + VKW + +
Sbjct: 2379 YSFTIPALGLSTSGRVSVYSVDVITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQ 2438
Query: 493 LTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIA 552
+ ++ + K G + L+IN D G Y L + L V+ K+++ + +
Sbjct: 2439 IKPDDRVQAIVK--GTKQRLVINRTHASDEGPYKLIVGRVETNCNLSVE--KIKIIRGLR 2494
Query: 553 DLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEA 612
DL VF+ E+S + +W KE+ P S+ K+ G+++KLT+ ++ DE
Sbjct: 2495 DLTCTETQNVVFEVELSHSGIDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEG 2554
Query: 613 DYSF 616
Y+F
Sbjct: 2555 KYTF 2558
Score = 91.3 bits (225), Expect = 5e-18
Identities = 107/447 (23%), Positives = 169/447 (37%), Gaps = 74/447 (16%)
Query: 846 VYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYS 905
V A N+ G + + + GPP P ++VS V + W PP G + Y
Sbjct: 18012 VTATNSAGTATENLSVIVLEKPGPPVGPVRF--DEVSADFVVISWEPPAYTGGCQISNYI 18069
Query: 906 VEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQ 965
VE + W + T+I + L TG FR+ A N G AP+ + + V VQ
Sbjct: 18070 VEKRDTTTTTW-HMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKSAPLDS-KAVIVQ 18127
Query: 966 EILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKE----GQPLAGEEVSI 1021
+ P G P + K + V W + G + G +
Sbjct: 18128 YPFKEP----------------GPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQ 18171
Query: 1022 RNSPTDTILFIRAARRVHSGT------------YQVTVRIENME--------DKATLVLQ 1061
+ ++IL+++ + T Y+ V EN+ + +
Sbjct: 18172 KEK--NSILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARD 18229
Query: 1062 VVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTV-LEHYR 1120
D P P+ + +T NV L+WK P G +++ GY V+K D W +
Sbjct: 18230 PCDPPGRPEAIVITRN---NVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVL 18286
Query: 1121 RTHCVVPELIIGNGYYFRVFSQNMVGF------SDRAATTKEPVFIPRPGITYEPPNYKA 1174
T V L+ Y FRV ++N G S A T ++ + P + P YK
Sbjct: 18287 ETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLD---PKYKD 18343
Query: 1175 LDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGED-ARFRMFSKQ 1233
+ V AG T +L +RG P P + W K+G +L E AR + S
Sbjct: 18344 VIV--------------VHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTI 18389
Query: 1234 GVLTLEIRKPCPFDGGIYVCRATNLQG 1260
TL ++ DGG Y+ + +N+ G
Sbjct: 18390 QKTTLVVKDCIRTDGGQYILKLSNVGG 18416
Score = 90.9 bits (224), Expect = 7e-18
Identities = 68/227 (29%), Positives = 112/227 (49%), Gaps = 8/227 (3%)
Query: 386 ELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSL--ADDAAYQCVVGGEKC 443
E+++ D +W G+ ++ S + I ++ G KR LT+ + L A + YQ +
Sbjct: 5047 EISEADIPGQWKLKGELLRPSPTCEI-KAEGGKRFLTLHKVKLDQAGEVLYQAL--NAIT 5103
Query: 444 STELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRF 503
+ L VKE + PL+D V ++ FEC ++ E A V W K G ++ + K+
Sbjct: 5104 TAILTVKEIELDFAVPLKDVTVPERRQARFECVLTRE-ANVIWSK-GPDIIKSSD-KFDI 5160
Query: 504 KKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAV 563
DG++H L+IN++ +D G Y G + A L V +L+ + D V + A
Sbjct: 5161 IADGKKHILVINDSQFDDEGVYTAEVEGKKTSARLFVTGIRLKFMSPLEDQTVKEGETAT 5220
Query: 564 FKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPAD 610
F CE+S E + VW KN +L + +S G+ HKL + +VT D
Sbjct: 5221 FVCELSHEKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDD 5267
Score = 90.5 bits (223), Expect = 9e-18
Identities = 108/430 (25%), Positives = 157/430 (36%), Gaps = 64/430 (14%)
Query: 868 GPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHT 927
GPP P + D+ SL W P G + Y VE C +WV AL +T+ T
Sbjct: 12621 GPPQPP--FDISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTK-T 12677
Query: 928 SILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKV 987
S V L G +FRVRA N G P+T+ P+ + Q
Sbjct: 12678 SCRVGKLIPGQEYIFRVRAENRFGISEPLTS-----------------PKMVAQFPFGVP 12720
Query: 988 GEPVNLLIPFQGKPRPQVTWTKE----GQPLAGEEVSIRNSPTDTILFIRAARR-VHSGT 1042
EP N + K V W + G P+ G I +++L+++A V S
Sbjct: 12721 SEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIG--YLIERKERNSLLWVKANDTLVRSTE 12778
Query: 1043 YQVTVRIENME----------------DKATLVLQVVDKPSPPQDLRVTDAWGLNVALEW 1086
Y +E +E K T + PP V D V+L W
Sbjct: 12779 YPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIW 12838
Query: 1087 KPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNG------YYFRVF 1140
P+ G +++ GY V+ +W + H + E G Y FR
Sbjct: 12839 ARPKHDGGSKIIGYFVEACKLPGDKW---VRCNTAPHQIPQEEYTATGLEEKAQYQFRAI 12895
Query: 1141 SQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAML 1200
++ V S + + +PV I + PP +D S A +V AG L
Sbjct: 12896 ARTAVNISPPSEPS-DPVTILAENV---PPR---IDLSVAMKSLL-----TVKAGTNVCL 12943
Query: 1201 CCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQG 1260
V G P P +SW K+G L +M ++ + TLE+ D G Y A N G
Sbjct: 12944 DATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSG 13003
Query: 1261 EARCECRLEV 1270
+L+V
Sbjct: 13004 SKSATIKLKV 13013
Score = 90.5 bits (223), Expect = 9e-18
Identities = 111/461 (24%), Positives = 182/461 (39%), Gaps = 71/461 (15%)
Query: 727 VETTKDRSIFTVEGAEKEDEGVYTVTVKNPVG---EDQVNLTVKVIDVPDAPAAPKISNV 783
++ TK ++ EG E E + V+ +N VG +V+ D D P P+ +
Sbjct: 18187 IQDTKFKTTGLDEGLEYE----FKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAIVI 18242
Query: 784 GEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYE 843
++ T++W+ PAYDGG I GYI+E+K RWM+ +F + E ++E YE
Sbjct: 18243 TRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGLVEDQRYE 18302
Query: 844 MRVYAVNAIG-MSRPSPASQPFM---PIGPPSEPTHLAVEDV-----SDTTV---SLKWR 891
RV A NA G S PS +S I P+ +DV +T V ++ +
Sbjct: 18303 FRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVHAGETFVLEADIRGK 18362
Query: 892 PPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAG 951
P V DG +E ++ + T+++VKD + ++ N+ G
Sbjct: 18363 PIPDV-VWSKDGKELEETAARME-----IKSTIQKTTLVVKDCIRTDGGQYILKLSNVGG 18416
Query: 952 PGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVN-LLIPFQGKPRPQVTWTKE 1010
T + P+TV ++L RP G P L + + + W
Sbjct: 18417 -----TKSIPITV-KVLDRP----------------GPPEGPLKVTGVTAEKCYLAWNPP 18454
Query: 1011 GQPLAGEEVS---IRNSPTDTILFIRAARRVHSGTYQVTVRI------------------ 1049
Q G +S I T + + + + V + Y+VT +
Sbjct: 18455 LQD-GGANISHYIIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGIG 18513
Query: 1050 ENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKT 1109
E +E P PP V+ ++ + W P D G TE+ GY ++K DK+
Sbjct: 18514 EPLESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEG 18573
Query: 1110 MEWFTV-LEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSD 1149
+ W + V L G+ Y FRV ++N G +
Sbjct: 18574 VRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGE 18614
Score = 89.0 bits (219), Expect = 3e-17
Identities = 135/650 (20%), Positives = 234/650 (36%), Gaps = 98/650 (15%)
Query: 661 VVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPD------------APEDTGDS 708
V A NK + P+ DP V+ Q T + AP P P PE G S
Sbjct: 21754 VSAVNKFGVGRPLDSDP---VVAQIQYTVPD-APGIPEPSNITGNSITLTWARPESDGGS 21809
Query: 709 D--EWVFDKKLLCETEGRVRVETTKDRSI----FTVEGAEKEDEGVYTVTVKNPVGEDQV 762
+ +++ +++ E + V+ R I F V G + +E + V +N G
Sbjct: 21810 EIQQYILERR---EKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVGPA 21866
Query: 763 NLTVKVI------DVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSY 816
+ ++I + P P K+++ + + +++W P +DGG I+GYI+E K
Sbjct: 21867 SGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLG 21926
Query: 817 RWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIG----------MSRPSPASQPFMP 866
W ++N + + + + G Y+ RV A+N G + + P +
Sbjct: 21927 DWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIKAVDRLTAPELD 21986
Query: 867 IGPPSEPTHLAVEDVS---------DTTVSLKWRPPE-----RVGAGGLDGYSVEYCPEG 912
I + TH+ S T + W P+ R D +S E
Sbjct: 21987 IDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADIHTTDSFST-LTVEN 22045
Query: 913 CSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQ--R 970
C+ A LT V++ + F V+ + GP P+T + L
Sbjct: 22046 CNRNDAGKYTLT------VENNSGSKSITFTVKVLDTPGPPGPITFKDVTRGSATLMWDA 22099
Query: 971 PRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTIL 1030
P L + + +K + + +W + + + +
Sbjct: 22100 PLLDGGARIHHYVVEK-------------REASRRSWQVISEKCTRQIFKVNDLAEGVPY 22146
Query: 1031 FIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQ 1090
+ R + Y V E E + ++P+PP+ L V D + L W P
Sbjct: 22147 YFRVSA---VNEYGVGEPYEMPEP-----IVATEQPAPPRRLDVVDTSKSSAVLAWLKPD 22198
Query: 1091 DVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDR 1150
G + + GY ++ K + W H ++ V L+ Y FRV ++N G+S+
Sbjct: 22199 HDGGSRITGYLLEMRQKGSDFWVEA-GHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEP 22257
Query: 1151 AATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKP 1210
V I P I EP ++ T L+ AG + + G P P
Sbjct: 22258 REAFSS-VIIKEPQI--EPT-------ADLTGITNQLITCK--AGSPFTIDVPISGRPAP 22305
Query: 1211 KISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQG 1260
K++W + L E R + + + TL ++ D G Y N G
Sbjct: 22306 KVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAG 22355
Score = 87.8 bits (216), Expect = 6e-17
Identities = 96/405 (23%), Positives = 160/405 (39%), Gaps = 38/405 (9%)
Query: 359 EKKSTAFQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAK 418
E + F+K ++ + K + E+++ D V+W+K+ QE+Q++ I +
Sbjct: 3008 EARHIEFRKHIKDIKVLEK-KRAMFECEVSEPDITVQWMKDDQELQITDRIKIQKEKYVH 3066
Query: 419 RTLTISQCSLADDAAYQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVS 478
R L I ++D Y V GG + +LFV+ V I ++ V+ QR E EV+
Sbjct: 3067 RLL-IPSTRMSDAGKYTVVAGGNVSTAKLFVEGRDVRIRSIKKEVQVIEKQRAVVEFEVN 3125
Query: 479 EEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAEL 538
E+ W KDG+E+ + ++++ + + H + I+E DAG Y ++ L
Sbjct: 3126 EDDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVTL 3185
Query: 539 IVQ-EKKLEVYQSIADLMVGAKDQAVFKCEVSDENVRGV-WLKNGKELVPDSRIKVSHIG 596
V + +V Q + + V + A F +S + W K + L + K H G
Sbjct: 3186 YVNAPEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDG 3245
Query: 597 RVHKLTIDDVTPADEADYSFVPEG--FACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGR 654
+ + L + + P D A Y+ + SA L +EV P QE P
Sbjct: 3246 QEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLS-VEVPEVVSPDQEMPVYPPAIITP 3304
Query: 655 IPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFD 714
+ DT V G R +SG + K D
Sbjct: 3305 LQDT-VTSEGQPARFQCRVSGTDLKVSWYSK----------------------------D 3335
Query: 715 KKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGE 759
KK+ + R+ +D + A EDEG YT N VG+
Sbjct: 3336 KKI--KPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQ 3378
Score = 86.7 bits (213), Expect = 1e-16
Identities = 71/263 (26%), Positives = 119/263 (45%), Gaps = 10/263 (3%)
Query: 375 VSKGHKIRLTVELADHDA-EVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAA 433
V +G K L +++ D VKW N ++I+ G K+ L I++ +D+
Sbjct: 2410 VIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVK-GTKQRLVINRTHASDEGP 2468
Query: 434 YQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVEL 493
Y+ +VG + + L V++ + I R L D Q V FE E+S G V W E+
Sbjct: 2469 YKLIVGRVETNCNLSVEK--IKIIRGLRDLTCTETQNVVFEVELSHSGIDVLWNFKDKEI 2526
Query: 494 TREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIAD 553
+ + KY+ + G+ + L + M +D G Y +L V + + + D
Sbjct: 2527 --KPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTFYAGENMTSGKLTVAGGAIS--KPLTD 2582
Query: 554 LMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEAD 613
V +AVF+CEV++ + +G WL++GK L + I+ G +L I D +
Sbjct: 2583 QTVAESQEAVFECEVANPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGE 2642
Query: 614 YSFVPEGFACNLSAKLHFMEVKI 636
Y++ + SAKL VKI
Sbjct: 2643 YTY--KVATSKTSAKLKVEAVKI 2663
Score = 86.7 bits (213), Expect = 1e-16
Identities = 156/799 (19%), Positives = 296/799 (37%), Gaps = 121/799 (15%)
Query: 1 MPEPGKKPVSAFSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASN--KYGLA 58
+P ++ F K S E+A + V E+ RA +V W + G + + ++ +
Sbjct: 26340 LPVSAPPKITQFLKAEASKEIAKLT-CVVESSVLRAK-EVTWYKDGKKLKENGHFQFHYS 26397
Query: 59 TEGTRHTLTVREVGPADQGSYAVI----AGSSKVKFDLKVIEAEKAEPMLAPAPAPAEAT 114
+GT + L + + +DQG Y G+SK +A
Sbjct: 26398 ADGT-YELKINNLTESDQGEYVCEISGEGGTSKTNLQFM-----------------GQAF 26439
Query: 115 GAPGEAPAPAAELGESAPSPKGSSSAALNGPTPGAPDDPIG---LFVMRPQDGEVTVGGS 171
+ E + +E +S K + S P AP+ PI + V QD V+
Sbjct: 26440 KSIHEKVSKISETKKS--DQKTTESTVTRKTEPKAPE-PISSKPVIVTGLQDTTVSSDSV 26496
Query: 172 ITFSARVAGASLLKPPVVKWFK-GKWVDLSSKVGQHLQLHDSYDRASKVYLFELHITDAQ 230
F+ + G P W K GK + K S D+ + E+H TD
Sbjct: 26497 AKFAVKATGEPR---PTAIWTKDGKAITQGGKYKL------SEDKGG--FFLEIHKTDTS 26545
Query: 231 PAFTGSYRCEVSTKDKFDCSNFNLTVHEAMGTGDLDLLSAFRRTSLAGGGRRISDSHEDT 290
+ G Y C V S+ LT+ +A+ + +S + + + + +
Sbjct: 26546 DS--GLYTCTVKNSAGSVSSSCKLTI-KAIKDTEAQKVSTQKTSEITPQKKAVVQEEISQ 26602
Query: 291 GILDFSSLLKKRDSFRTPRDSKLEAPAEEDVWEILRQAPPSEYERIAFQYGVTDLRGMLK 350
L S +K ++ + + E ++ + E ++++ + E+ +T
Sbjct: 26603 KALR-SEEIKMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEEITKT----- 26656
Query: 351 RLKGMRRDEKKSTAFQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKY 410
+E ++ A K +++G ++ L +A +VKW+ NG E+ S +Y
Sbjct: 26657 ---SQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAGA-TDVKWVLNGVELTNS-EEY 26711
Query: 411 IFESIGAKRTLTISQCSLADDAAYQCV----VGGEKCSTELF----VKEPPVLITRPLED 462
+ G+ +TLTI Q S D+ C+ G KC +L + + P I++P
Sbjct: 26712 RYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTLSKELSDAPAFISQP-RS 26770
Query: 463 QLVMVGQRVEFECEVS-EEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLED 521
Q + GQ V F CE+S E +++W K+ + ++ + + L I A + D
Sbjct: 26771 QNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVS--ISRSRNVYSLEIRNASVSD 26828
Query: 522 AGHYAL--------CTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDENV 573
+G Y + C++ + +V+E EV ++ + S ++V
Sbjct: 26829 SGKYTIKAKNFRGQCSATASLMVLPLVEEPSREV-------VLRTSGDTSLQGSFSSQSV 26881
Query: 574 RGVWLKNGKELVPDSRIKVSHIGRVH--KLTIDDVTPADEADYSFVPEGF--ACNLSAKL 629
+ K S S + + ++ ++ E+ F N++
Sbjct: 26882 QMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQLE 26941
Query: 630 HFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQ 689
+ R PPKI +P I + G L + +G+P P V W
Sbjct: 26942 SSTSKMLKAGIRGIPPKIE-----ALPSDISIDEGKVLTVACAFTGEPTPEVTWSCG--- 26993
Query: 690 GNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVY 749
+K+ + +GR +E T D + + +K+D G+Y
Sbjct: 26994 ------------------------GRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLY 27029
Query: 750 TVTVKNPVGEDQVNLTVKV 768
T+++ N G D + + +
Sbjct: 27030 TLSLGNEFGSDSATVNIHI 27048
Score = 86.3 bits (212), Expect = 2e-16
Identities = 67/265 (25%), Positives = 115/265 (43%), Gaps = 6/265 (2%)
Query: 375 VSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAY 434
V +G EL+ V W KN ++ S + + S G L + + +L D +
Sbjct: 5213 VKEGETATFVCELSHEKMHVVWFKNDAKLHTSRT-VLISSEGKTHKLEMKEVTLDDISQI 5271
Query: 435 QCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELT 494
+ V + +L V E T L D+ + + +CEVS++ VKW KDG E+
Sbjct: 5272 KAQVKELSSTAQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVSKD-VPVKWFKDGEEIV 5330
Query: 495 REETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADL 554
KY K DG R L I +A L+D G Y + A + V+ + ++V + + +
Sbjct: 5331 PSP--KYSIKADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIKVEKPLYGV 5388
Query: 555 MVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADY 614
V + A F+ E+S+ +V G W G+ L ++ G+ H L + + +
Sbjct: 5389 EVFVGETAHFEIELSEPDVHGQWKLKGQPLTASPDCEIIEDGKKHILILHNCQLGMTGEV 5448
Query: 615 SFVPEGFACNLSAKLHFMEVKIDFV 639
SF + +A L E+ + F+
Sbjct: 5449 SF--QAANAKSAANLKVKELPLIFI 5471
Score = 85.9 bits (211), Expect = 2e-16
Identities = 106/418 (25%), Positives = 147/418 (35%), Gaps = 55/418 (13%)
Query: 868 GPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHT 927
GPP+ P + ++VS V+ W PPE G + Y VE + WV L T
Sbjct: 14788 GPPTGP--IKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVE-LATTVIRT 14844
Query: 928 SILVKDLPTGARLLFRVRAHNMAGPGAPVTTT-----EPVTVQEILQRPRLQLPRHLRQT 982
+ L TG FRV+A N G G +T+ P V P++ T
Sbjct: 14845 TYKATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMT 14904
Query: 983 IQ-----KKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARR 1037
I G P+ L + K R + W + L + + TD I
Sbjct: 14905 ISWHEPLSDGGSPI-LGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGI-------- 14955
Query: 1038 VHSGTYQVTVRIENMEDKAT--------LVLQVVDKPSPPQDLRVTDAWGLNVALEWKPP 1089
Y+ V ENM K+ L L +D P P L +T V L+W P
Sbjct: 14956 ----AYEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRH---TVTLKWAKP 15008
Query: 1090 QDVGNTELWGYTVQKADKKTMEWFTV-LEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFS 1148
+ G ++ Y V+K D W + V L Y FRV ++N
Sbjct: 15009 EYTGGFKITSYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKN----- 15063
Query: 1149 DRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVI---AGYTAMLCCAVR 1205
AA P P IT D EAP + + + AG L V
Sbjct: 15064 --AAGAISPPSEPSDAITCR-------DDVEAPKIKVDVKFKDTVILKAGEAFRLEADVS 15114
Query: 1206 GSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEAR 1263
G P P + W K+G +L A+ + L + D G Y ATN G A+
Sbjct: 15115 GRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGGFAK 15172
Score = 85.9 bits (211), Expect = 2e-16
Identities = 99/432 (22%), Positives = 160/432 (37%), Gaps = 45/432 (10%)
Query: 846 VYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYS 905
+ N +G S PP P +DVS +++L W PP G + Y
Sbjct: 16930 ITVANVVGQKTASIEIVTLDKPDPPKGPVKF--DDVSAESITLSWNPPLYTGGCQITNYI 16987
Query: 906 VEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQ 965
V+ + W + T++ V L TG FR+ A N G + + +P+ Q
Sbjct: 16988 VQKRDTTTTVW-DVVSATVARTTLKVTKLKTGTEYQFRIFAENRYGQSFALES-DPIVAQ 17045
Query: 966 EILQRPRLQ----LPRHLRQTIQKKVGEPVN------LLIPFQGKPRPQVTWTKEGQPLA 1015
+ P + ++ + EPVN + + K R + WTK + +
Sbjct: 17046 YPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKTII 17105
Query: 1016 GEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVT 1075
+ + + I + RV++ V V + + + D P P+ + V
Sbjct: 17106 HDTQFKAQNLEEGIEY---EFRVYAENI-VGVGKASKNSECYVARDPCDPPGTPEPIMVK 17161
Query: 1076 DAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTV-LEHYRRTHCVVPELIIGNG 1134
+ L+W P G + + GY V+K D W + T V L
Sbjct: 17162 RN---EITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQR 17218
Query: 1135 YYFRVFSQNMVGFSDRAA------TTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLV 1188
Y FRV ++N G + + T K+ V +PR S P F +V
Sbjct: 17219 YEFRVIAKNAAGAISKPSDSTGPITAKDEVELPR--------------ISMDPKFRDTIV 17264
Query: 1189 NRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDG 1248
V AG T L V G P P I W + ++ E AR + + L ++ DG
Sbjct: 17265 ---VNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDG 17321
Query: 1249 GIYVCRATNLQG 1260
G Y+ RA+N+ G
Sbjct: 17322 GQYILRASNVAG 17333
Score = 85.5 bits (210), Expect = 3e-16
Identities = 109/404 (26%), Positives = 150/404 (37%), Gaps = 61/404 (15%)
Query: 847 YAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSV 906
Y V A + A + P +L + DVS ++ W PPE G + Y +
Sbjct: 11902 YVVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYIL 11961
Query: 907 EYCPEGCSEWVA-ALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQ 965
E C W + LT T+ V L G +FRVRA N G G P T ++PV
Sbjct: 11962 EKCETKRMVWSTYSATVLTPGTT--VTRLIEGNEYIFRVRAENKIGTGPP-TESKPV--- 12015
Query: 966 EILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKE----GQPLAG----- 1016
+ +T K G P + K V W G+ + G
Sbjct: 12016 -------------IAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLEK 12062
Query: 1017 -EEVSIRNSPTDTILFIRAARRVHS----GTYQVTVRIEN--------MEDKATLVLQVV 1063
E+ S R P + +V + YQ V+ EN + + + +
Sbjct: 12063 KEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPI 12122
Query: 1064 DKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQK----ADKKTMEWF---TVL 1116
+ P PP + RV D ++ L W P G + GY V+ AD E +
Sbjct: 12123 EPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAA 12182
Query: 1117 EHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALD 1176
R V L Y FRV +QN VG R A KE + +P EPP LD
Sbjct: 12183 AQLVRKEFTVTSLDENQEYEFRVCAQNQVGIG-RPAELKEAI---KPKEILEPPEID-LD 12237
Query: 1177 FSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLD 1220
S + LV V AG L VRG P PK++W K G+D
Sbjct: 12238 AS-----MRKLV--IVRAGCPIRLFAIVRGRPAPKVTWRKVGID 12274
Score = 85.5 bits (210), Expect = 3e-16
Identities = 110/462 (23%), Positives = 181/462 (39%), Gaps = 59/462 (12%)
Query: 769 IDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQE 828
+D D P P N+ + T++W P Y GG I YI+E++ + RW++ NF I E
Sbjct: 14982 LDPIDPPGKPVPLNITRHTVTLKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILE 15041
Query: 829 LSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSL 888
+ E YE RV A NA G P + E + V+ TV L
Sbjct: 15042 NEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVIL 15101
Query: 889 KWRPPERVGA--GGLDGYSVEYCPEGCS-EWVAALQGLTE--HTSILVKDL--------- 934
K R+ A G ++E+ +G E A L+ T+++ KD
Sbjct: 15102 KAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYT 15161
Query: 935 -----PTG-ARLLFRVRAHNMAG-PGAPVTTTEPVTVQEILQ-RPRLQLPRHLRQTIQKK 986
P G A+ +F V+ + G P P+ TE + + +L P L
Sbjct: 15162 LTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFPPLD-----------D 15210
Query: 987 VGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRN--SPTDTILFIRAARRVHSGTYQ 1044
G ++ I Q + ++ WT + ++ + + I + A + G
Sbjct: 15211 GGAKIDHYI-VQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYGVG--- 15266
Query: 1045 VTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQK 1104
E +E + L + P PP++ VT ++ + W P G +E+ Y V++
Sbjct: 15267 -----EPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVER 15321
Query: 1105 ADKKTMEWFTV-LEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTK-----EPV 1158
DK W + V L G+ Y FR+ ++N G S + T+ + V
Sbjct: 15322 RDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTV 15381
Query: 1159 FIPRPGITYEPPNYKALDFSEAP---SFTQPLVN-RSVIAGY 1196
F P P P N + LD S + ++ +P+ + S I GY
Sbjct: 15382 FKPGP-----PGNPRVLDTSRSSISIAWNKPIYDGGSEITGY 15418
Score = 85.5 bits (210), Expect = 3e-16
Identities = 66/214 (30%), Positives = 97/214 (45%), Gaps = 18/214 (8%)
Query: 1064 DKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVL-EHYRRT 1122
+KP P +T + + WKPP G ++ Y ++K +KK +W +V E R T
Sbjct: 24451 EKPGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRET 24510
Query: 1123 HCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPS 1182
V LI G Y FRV +N+ G S+ + + EP+ P+ + + P++K
Sbjct: 24511 VFSVKNLIEGLEYEFRVKCENLGGESEWSEIS-EPI-TPKSDVPIQAPHFK--------- 24559
Query: 1183 FTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDA---RFRMFSKQGVLTLE 1239
+ L N +V A L C V G PKP + W++ G ++ D R + F K G L
Sbjct: 24560 --EELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEF-KGGYHQLI 24616
Query: 1240 IRKPCPFDGGIYVCRATNLQGEARCECRLEVRVP 1273
I D +Y RATN G LEV VP
Sbjct: 24617 IASVTDDDATVYQVRATNQGGSVSGTASLEVEVP 24650
Score = 83.2 bits (204), Expect = 1e-15
Identities = 95/446 (21%), Positives = 169/446 (37%), Gaps = 71/446 (15%)
Query: 367 KKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGS---KYIFESIGAKRTLTI 423
+ ++ QV + + + E+ + D + W K+G EI KY+ E + I
Sbjct: 3104 RSIKKEVQVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYVVER--RIHRMFI 3161
Query: 424 SQCSLADDAAYQCVVGGEKCSTELFVKEP-PVLITRPLEDQLVMVGQRVEFECEVS-EEG 481
S+ +D Y V G + S L+V P P + + L+ V G+ F +S
Sbjct: 3162 SETRQSDAGEYTFVAGRNRSSVTLYVNAPEPPQVLQELQPVTVQSGKPARFCAVISGRPQ 3221
Query: 482 AQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALA----- 536
++ W K+ E FK +F DGQ + L++ EA EDA Y +A
Sbjct: 3222 PKISWYKE--EQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSAS 3279
Query: 537 ------ELIVQEKKLEVYQS-----IADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELV 585
E++ ++++ VY + D + A F+C VS +++ W K++
Sbjct: 3280 LSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKKIK 3339
Query: 586 PDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHF-MEVKIDFVPRQEP 644
P +++ ++L I + P DE Y+FV +S+ + +E F
Sbjct: 3340 PSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEGFSKFEENTSN 3399
Query: 645 PKIHLDCP--------GRIPDTIVVVA------GNKLRLDVPISGDPAPTVIWQKAITQG 690
+ H+ G+ P I ++ G +R +SG P P +
Sbjct: 3400 SQWHVSLSVSFKKEPLGQKPSFIQPLSSLRVHNGETVRFHARVSGIPKPEI--------- 3450
Query: 691 NKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRV-RVETTKDRSIFTVEGAEKEDEGVY 749
+W +++L+ T+ V E + ++ + A E G Y
Sbjct: 3451 -------------------QWFHNQQLILPTKDVVFHFEESTGMALMLIVDAYSEHAGQY 3491
Query: 750 TVTVKNPVGEDQVNLTVKVIDVPDAP 775
+ N GE T+ V P AP
Sbjct: 3492 SCKAANSAGEATCAATLTV--TPKAP 3515
Score = 82.0 bits (201), Expect = 3e-15
Identities = 91/374 (24%), Positives = 142/374 (37%), Gaps = 41/374 (10%)
Query: 868 GPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHT 927
GPP+ P + ++++ T++++ W PPE G L GY VE W+ + +T T
Sbjct: 23461 GPPTGP--IKIDEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRST 23518
Query: 928 SILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKV 987
+ L G +FRV A N G G+ + + V E R+ P Q
Sbjct: 23519 FKFTR-LTEGNEYVFRVAATNRFGIGSYLQSE----VIECRSSIRIPGPPETLQIFDVSR 23573
Query: 988 GEPVNLLIPFQGKPRPQVTW--TKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQV 1045
P + QVT + + A V + P T+ R+ Y+
Sbjct: 23574 DGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPV-TMTRYRSTGLTEGLEYEH 23632
Query: 1046 TVRIENME--------DKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTEL 1097
V N K + + + P PQ+ RVTD +V+L W P+D G +++
Sbjct: 23633 RVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKV 23692
Query: 1098 WGYTVQKADKKTMEWF------TVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRA 1151
GY ++ EW T + Y TH +P+ G Y FRV + N G
Sbjct: 23693 TGYLIEMQKVDQHEWTKCNTTPTKIREYTLTH--LPQ---GAEYRFRVLACNAGG----- 23742
Query: 1152 ATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPK 1211
EP +P E Y + E + + + R G L ++G P P
Sbjct: 23743 --PGEPAEVPGTVKVTEMLEYPDYELDER--YQEGIFVRQ---GGVIRLTIPIKGKPFPI 23795
Query: 1212 ISWFKNGLDLGEDA 1225
W K G D+ + A
Sbjct: 23796 CKWTKEGQDISKRA 23809
Score = 81.3 bits (199), Expect = 6e-15
Identities = 100/418 (23%), Positives = 150/418 (35%), Gaps = 61/418 (14%)
Query: 870 PSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSI 929
P P + + +VS +L W PP G + Y +E W + + +
Sbjct: 14101 PGPPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHV 14160
Query: 930 LVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGE 989
K L G +FRV A N G G PV + EPV + + P G
Sbjct: 14161 ATK-LIQGNEYIFRVSAVNHYGKGEPVQS-EPVKMVDRFGPP----------------GP 14202
Query: 990 PVNLLIPFQGKPRPQVTWTKE----GQPLAGEEVSIRNSPTDTILFIRAARRVHS----- 1040
P + K V+W + G + G V R + + ++RA + S
Sbjct: 14203 PEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKS--LRWVRAIKTPVSDLRCK 14260
Query: 1041 -------GTYQVTVRIENME--------DKATLVLQVVDKPSPPQDLRVTDAWGLNVALE 1085
TY+ V EN + L+ P PP + VTD + +L
Sbjct: 14261 VTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLA 14320
Query: 1086 WKPPQDVGNTELWGYTVQKADKKTMEWF--TVLEHYRRTHCVVPELIIGNGYYFRVFSQN 1143
W P G E+ GY V+ W T R T VVP+L Y FR+ + N
Sbjct: 14321 WGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAIN 14380
Query: 1144 MVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCA 1203
G EP IP I A DF + LV R AG + +
Sbjct: 14381 DAGVG-------EPAVIPDVEIVERE---MAPDFELDAELRRTLVVR---AGLSIRIFVP 14427
Query: 1204 VRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGE 1261
++G P P+++W K+ ++L A + + L I + +D G +V N G+
Sbjct: 14428 IKGRPAPEVTWTKDNINLKNRANIE--NTESFTLLIIPECNRYDTGKFVMTIENPAGK 14483
Score = 78.2 bits (191), Expect = 5e-14
Identities = 70/236 (29%), Positives = 112/236 (47%), Gaps = 14/236 (5%)
Query: 396 WLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVV---GGEKCST-ELFVKE 451
W+K+G I+ S K+ F + G R L I L+D Y CV+ EK ST +L V+E
Sbjct: 4779 WMKDGSNIRES-PKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEE 4837
Query: 452 PPVLITRPLEDQLVMV-GQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKKDGQRH 510
PV + LE+++ +V GQ + CE+++E V W KDG ++ E+ + G
Sbjct: 4838 LPVRFVKTLEEEVTVVKGQPLYLSCELNKE-RDVVWRKDG-KIVVEKPGRIVPGVIGLMR 4895
Query: 511 HLIINEAMLEDAGHYALCTSGGQAL----AELIVQEKKLEVYQSIADLMVGAKDQAVFKC 566
L IN+A DAG Y + L +V+ + + + I D V K A+F C
Sbjct: 4896 ALTINDADDTDAGTYTVTVENANNLECSSCVKVVEVIRDWLVKPIRDQHVKPKGTAIFAC 4955
Query: 567 EVSDENVRGVWLKNGKEL--VPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEG 620
+++ + W K E+ P+ + ++ G L I + P D A+Y+ EG
Sbjct: 4956 DIAKDTPNIKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEG 5011
Score = 77.8 bits (190), Expect = 6e-14
Identities = 98/433 (22%), Positives = 154/433 (35%), Gaps = 42/433 (9%)
Query: 847 YAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSV 906
Y + A S A+ + P P + + + L W PP G + Y V
Sbjct: 12994 YTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIV 13053
Query: 907 EYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQE 966
+ W A + TS V+ L G FR+ A N G G PV T EP +
Sbjct: 13054 DKRETSRPNW-AQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFT-EPAIAKN 13111
Query: 967 ILQRPRLQLPRHLRQTIQKKV-----------GEPVNLLIPFQGKPRPQVTWTKEGQ-PL 1014
P P + + + G P+ + + + V WTK + P+
Sbjct: 13112 PYDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYL-LEKRETQAVNWTKVNRKPI 13170
Query: 1015 AGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRV 1074
+ T R +G + + KA P PP +V
Sbjct: 13171 IERTLKATGLQEGTEYEFRVTAINKAGPGK-----PSDASKAAYARDPQYPPGPPAFPKV 13225
Query: 1075 TDAWGLNVALEWKPPQDVGNTELWGYTVQ--KADKKTMEWFTVLEHYRRTHCVVPELIIG 1132
D +V+L W P G + + GY V+ +AD + ++ ++T V L+
Sbjct: 13226 YDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMED 13285
Query: 1133 NGYYFRVFSQNMVGFSDRAATTKE----PVFIPRPGITYEPPNYKALDFSEAPSFTQPLV 1188
Y FRV++ N +G+SD + + + IP G LD + L+
Sbjct: 13286 TQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEG---------ELD----ADLRKTLI 13332
Query: 1189 NRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDG 1248
R AG T L V+G P PKI+W K ++L + + S L +D
Sbjct: 13333 LR---AGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDA 13389
Query: 1249 GIYVCRATNLQGE 1261
G Y+ N G+
Sbjct: 13390 GKYILTLENSCGK 13402
Score = 77.4 bits (189), Expect = 8e-14
Identities = 65/250 (26%), Positives = 112/250 (44%), Gaps = 8/250 (3%)
Query: 375 VSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAY 434
V++ + E+A+ D++ +WL++G+ + ++ + ES G KR L I+ L D Y
Sbjct: 2585 VAESQEAVFECEVANPDSKGEWLRDGKHLPLTNN-IRSESDGHKRRLIIAATKLDDIGEY 2643
Query: 435 QCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQ-VKWLKDGVEL 493
V K S +L V+ V I + L++ V Q F E++ + V+W+K+GV L
Sbjct: 2644 TYKVATSKTSAKLKVEA--VKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVL 2701
Query: 494 TREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIAD 553
E KY G + L I + D Y A A L V+ K + + D
Sbjct: 2702 ESNE--KYAISVKGTIYSLRIKNCAIVDESVYGFRLGRLGASARLHVETVK--IIKKPKD 2757
Query: 554 LMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEAD 613
+ F+ VS + V W E+ P + ++ +VHKL + +++P+D +
Sbjct: 2758 VTALENATVAFEVSVSHDTVPVKWFHKSVEIKPSDKHRLVSERKVHKLMLQNISPSDAGE 2817
Query: 614 YSFVPEGFAC 623
Y+ V C
Sbjct: 2818 YTAVVGQLEC 2827
Score = 77.4 bits (189), Expect = 8e-14
Identities = 52/242 (21%), Positives = 99/242 (40%), Gaps = 3/242 (1%)
Query: 374 QVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAA 433
+V + + + E++ +WLK QEI ++ G K ++ I + D+A
Sbjct: 5478 KVFEKDEAKFECEVSREPKTFRWLKGTQEIT-GDDRFELIKDGTKHSMVIKSAAFEDEAK 5536
Query: 434 YQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVEL 493
Y + S +L ++ + PL+D + F E+S + +VKW K+ L
Sbjct: 5537 YMFEAEDKHTSGKLIIEGIRLKFLTPLKDVTAKEKESAVFTVELSHDNIRVKWFKNDQRL 5596
Query: 494 TREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIAD 553
T + +G+ H + + ++D + G + A+L V E + D
Sbjct: 5597 --HTTRSVSMQDEGKTHSITFKDLSIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQD 5654
Query: 554 LMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEAD 613
KD+ + +CE+S + W K+GKE+ P + G+ L + +D
Sbjct: 5655 YTGVEKDEVILQCEISKADAPVKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQ 5714
Query: 614 YS 615
Y+
Sbjct: 5715 YT 5716
Score = 71.6 bits (174), Expect = 4e-12
Identities = 60/195 (30%), Positives = 92/195 (47%), Gaps = 17/195 (8%)
Query: 439 GGEKCSTEL----FVKEPPVLITRPLEDQLV----MVGQRVEFECEVSEEGAQVKWLKDG 490
GGEK E +K P+ + ++D ++ VG FEC VS A W+KDG
Sbjct: 4724 GGEKPPDEAPFTYQLKAVPLKFVKEIKDIILTESEFVGSSAIFECLVSPSTAITTWMKDG 4783
Query: 491 VELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQ----ALAELIVQEKKLE 546
+ E+ K+RF DG+ L I + L DAG Y G + A+L+V+E +
Sbjct: 4784 SNI--RESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEELPVR 4841
Query: 547 VYQSIADLMVGAKDQAVF-KCEVSDENVRGVWLKNGKELV-PDSRIKVSHIGRVHKLTID 604
+++ + + K Q ++ CE++ E VW K+GK +V RI IG + LTI+
Sbjct: 4842 FVKTLEEEVTVVKGQPLYLSCELNKER-DVVWRKDGKIVVEKPGRIVPGVIGLMRALTIN 4900
Query: 605 DVTPADEADYSFVPE 619
D D Y+ E
Sbjct: 4901 DADDTDAGTYTVTVE 4915
Score = 70.9 bits (172), Expect = 8e-12
Identities = 62/255 (24%), Positives = 106/255 (41%), Gaps = 6/255 (2%)
Query: 386 ELADHDAEVKWLKNGQEIQMS-GSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCS 444
++A +KW K EI K G L I D A Y + G++
Sbjct: 4956 DIAKDTPNIKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEGKRYP 5015
Query: 445 TELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFK 504
+L + E V + +P+ED + + F+ E+SE +W G L T + K
Sbjct: 5016 AKLTLGEREVELLKPIEDVTIYEKESASFDAEISEADIPGQWKLKGELLRPSPTCE--IK 5073
Query: 505 KDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVF 564
+G + L +++ L+ AG A L V+E +L+ + D+ V + QA F
Sbjct: 5074 AEGGKRFLTLHKVKLDQAGEVLYQALNAITTAILTVKEIELDFAVPLKDVTVPERRQARF 5133
Query: 565 KCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACN 624
+C ++ E +W K + + + G+ H L I+D DE Y+ EG
Sbjct: 5134 ECVLTRE-ANVIWSKGPDIIKSSDKFDIIADGKKHILVINDSQFDDEGVYTAEVEG--KK 5190
Query: 625 LSAKLHFMEVKIDFV 639
SA+L +++ F+
Sbjct: 5191 TSARLFVTGIRLKFM 5205
Score = 70.1 bits (170), Expect = 1e-11
Identities = 144/622 (23%), Positives = 227/622 (36%), Gaps = 79/622 (12%)
Query: 675 GDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRS 734
G P VI + +T K PA + TG ++ +KK L + T +
Sbjct: 18235 GRPEAIVITRNNVTLKWKKPAYDG--GSKITG----YIVEKKDLPDGRWMKASFTNVLET 18288
Query: 735 IFTVEGAEKEDEGVYTVTVKNPVG------EDQVNLTVK-VIDVPDAPAAPKISNVGEDS 787
FTV G ++ + V +N G + +T + ID P+A PK +V
Sbjct: 18289 EFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVH 18348
Query: 788 CTVQWEPPAYDGGQPILGYILERKKKKSYRWM-RLNF-DLIQELSHEARRMI--EGVVYE 843
+ A G+PI + + K+ R+ IQ+ + + I +G Y
Sbjct: 18349 AGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYI 18408
Query: 844 MRVYAVNAIGMSRPSPASQPFMPI-GPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLD 902
+++ + +G ++ P + + GPP P L V V+ L W PP + G +
Sbjct: 18409 LKL---SNVGGTKSIPITVKVLDRPGPPEGP--LKVTGVTAEKCYLAWNPPLQDGGANIS 18463
Query: 903 GYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPV 962
Y +E W + + K LP G +FRV A N G G P+ + PV
Sbjct: 18464 HYIIEKRETSRLSWTQVSTEVQALNYKVTKLLP-GNEYIFRVMAVNKYGIGEPLESG-PV 18521
Query: 963 TVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKE----GQPLAGEE 1018
T + P G P + K VTW + G + G
Sbjct: 18522 TACNPYKPP----------------GPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYI 18565
Query: 1019 VSIR----------NSPTDTILFIRAARRVHSGTYQVTVRIENME-----DKATLVLQVV 1063
+ R N T T L +R +Y+ V EN + ++ +
Sbjct: 18566 LEKRDKEGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRAC 18625
Query: 1064 DK---PSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEH-- 1118
D P PP + +VTD +V+L W P G + GY V+ + EW T
Sbjct: 18626 DALYPPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTG 18685
Query: 1119 YRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFS 1178
+ V +L Y FR+ + N G + A V R EPP + LD
Sbjct: 18686 LQGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQER----IEPPEIE-LD-- 18738
Query: 1179 EAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTL 1238
+ +V R A T L ++G P+P++ W K L + A+ + S +L +
Sbjct: 18739 --ADLRKVVVLR---ASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVI 18793
Query: 1239 EIRKPCPFDGGIYVCRATNLQG 1260
+ FD G Y N G
Sbjct: 18794 D--NVTRFDSGRYNLTLENNSG 18813
Score = 68.9 bits (167), Expect = 3e-11
Identities = 66/244 (27%), Positives = 95/244 (38%), Gaps = 30/244 (12%)
Query: 1034 AARRVHSGTYQVTVRIENME----------------DKATLVLQVVDKPSPPQDLRVTDA 1077
A + H TY+VT E E + T ++ + PSPP L + D
Sbjct: 14545 ATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDI 14604
Query: 1078 WGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYF 1137
V+L W P+ G +++ GY ++ K + +W T + + CVV L G Y F
Sbjct: 14605 TKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQW-THITTVKGLECVVRNLTEGEEYTF 14663
Query: 1138 RVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYT 1197
+V + N G R+A + RP I E LD Q LV AG
Sbjct: 14664 QVMAVNSAG---RSAPRES-----RPVIVKEQTMLPELDLR---GIYQKLVIAK--AGDN 14710
Query: 1198 AMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATN 1257
+ V G PKP ++W K L + R + L I + D G Y A N
Sbjct: 14711 IKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARN 14770
Query: 1258 LQGE 1261
+ GE
Sbjct: 14771 IVGE 14774
Score = 66.6 bits (161), Expect = 1e-10
Identities = 166/772 (21%), Positives = 275/772 (35%), Gaps = 163/772 (21%)
Query: 577 WLKNGKELVPD--SRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEV 634
W +G+++V D ++ + G L I TP+D +++ V + A S + +
Sbjct: 1444 WFHDGQQIVNDYTHKVVIKEDG-TQSLIIVPATPSDSGEWTVVAQNRAGRSSISVI---L 1499
Query: 635 KIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAP 694
++ V Q P + + G++L + V +G+P P ++W K
Sbjct: 1500 TVEAVEHQVKPMFVEKLKN-----VNIKEGSRLEMKVRATGNPNPDIVWLK--------- 1545
Query: 695 ARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVK 754
+SD V K ++R+E TK + ++ +D YT T
Sbjct: 1546 ------------NSDIIVPHKY------PKIRIEGTKGEAALKIDSTVSQDSAWYTATAI 1587
Query: 755 NPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKK 814
N G D V V V++ P +P I+ R
Sbjct: 1588 NKAGRDTTRCKVNV--------------------EVEFAEP-----EPERKLIIPRG--- 1619
Query: 815 SYRWMRLNFDLIQ--ELSHEARRMIEGVVYEMRVYA-------VNAIGMSRPSPASQP-- 863
+YR + ++ L + + EG +Y+ + ++ + R PA
Sbjct: 1620 TYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGPAHFECR 1679
Query: 864 FMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPE-GCSEWVAALQG 922
PIG P+ + D + + R G LD Y V Y + G A +
Sbjct: 1680 LTPIGDPTMVVEW-LHDGKPLEAANRLRMINEFGYCSLD-YGVAYSRDSGIITCRATNKY 1737
Query: 923 LTEHTS--ILVKD---------LPTGARLLFRVRA-HNMAGPGAPVTTTEPVTVQEILQR 970
T+HTS ++VKD LP G + L R+ MA GA T T Q+ Q+
Sbjct: 1738 GTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVT---TDQKEKQK 1794
Query: 971 PRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLA-GEEVSIRNSPTDTI 1029
P + L + ++ GE G P+P+V W GQ + + +R D I
Sbjct: 1795 PDIVL---YPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRY---DGI 1848
Query: 1030 LFIRAARRVHSGTYQVTVRIEN----MEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALE 1085
++ T +V V EN +E K L +Q +D R L A E
Sbjct: 1849 HYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQ------QREDFRSV----LRRAPE 1898
Query: 1086 WKPPQDVGNTELWGYTVQKADK-----KTMEWFTVLEHYRRTHCVVPELI---------- 1130
+P V + VQK D+ +T E + R TH VPE
Sbjct: 1899 PRPEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKVPEESEELRSKFKRR 1958
Query: 1131 IGNGYYFRV---------------------------FSQNMVGFSDRAATTKEPVFIPRP 1163
GYY + +++ + +A + + IP
Sbjct: 1959 TEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIP-- 2016
Query: 1164 GITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGE 1223
T++P + EAP + + +++V G A V G P P+ W+KNG+ +
Sbjct: 2017 --TFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIER 2074
Query: 1224 DAR-FRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVRVPQ 1274
R + + + V L IR D + +A N+ GE L V+ Q
Sbjct: 2075 SDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQ 2126
Score = 65.5 bits (158), Expect = 3e-10
Identities = 64/246 (26%), Positives = 101/246 (41%), Gaps = 35/246 (14%)
Query: 15 KPRSVEVAAGSPAVFEAETERAGVK-VRWQRGGSDISASNKYGLATEGTRHTLTVREVGP 73
KPRS+ V G A F +T+ V V W R G +S S ++ + T + T + V
Sbjct: 26194 KPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQA 26253
Query: 74 ADQGSYAVIA----GSSKVKFDLKVIEAEKAEPMLAPAPAPAEATGAPGEAPAPAAELGE 129
+D+G+Y+V+ G + +F L + +A E + P ++P P + E
Sbjct: 26254 SDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRV--------KSPEPRVKSPE 26305
Query: 130 SAPSPKGSSSAALNGPTPGAPDDPIGLFVMRPQDGEVTVGGSITFSAR------------ 177
+ SPK S + P +P + + Q V+ IT +
Sbjct: 26306 AVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPVSAPPKITQFLKAEASKEIAKLTC 26365
Query: 178 VAGASLLKPPVVKWFK-GKWVDLSSKVGQHLQLHDSYDRASKVYLFELHITDAQPAFTGS 236
V +S+L+ V W+K GK K H Q H S D +EL I + + G
Sbjct: 26366 VVESSVLRAKEVTWYKDGK----KLKENGHFQFHYSADGT-----YELKINNLTESDQGE 26416
Query: 237 YRCEVS 242
Y CE+S
Sbjct: 26417 YVCEIS 26422
Score = 63.5 bits (153), Expect = 1e-09
Identities = 102/453 (22%), Positives = 153/453 (33%), Gaps = 71/453 (15%)
Query: 820 RLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPAS-------QPFMPIGPPSE 872
R+N ++ L + + + VY V A S + A P +GP
Sbjct: 21630 RMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGP--- 21686
Query: 873 PTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVK 932
+ +++ ++L W P G + Y +E W A ++ E S
Sbjct: 21687 ---IRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAW-ALIEDKCEAQSYTAI 21742
Query: 933 DLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQ---EILQRPRLQLPRHLRQTI------ 983
L G FRV A N G G P+ + +PV Q + P + P ++
Sbjct: 21743 KLINGNEYQFRVSAVNKFGVGRPLDS-DPVVAQIQYTVPDAPGIPEPSNITGNSITLTWA 21801
Query: 984 --QKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSG 1041
+ G + I + + + W K I P F +
Sbjct: 21802 RPESDGGSEIQQYI-LERREKKSTRWVKV----------ISKRPISETRF-KVTGLTEGN 21849
Query: 1042 TYQVTVRIENME--------DKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVG 1093
Y+ V EN + + V+ P PP ++VTD V+LEW P G
Sbjct: 21850 EYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDG 21909
Query: 1094 NTELWGYTVQKADKKTMEWFTV-LEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAA 1152
E+ GY ++ +W V E +T V +L G Y FRV + N G D
Sbjct: 21910 GMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCE 21969
Query: 1153 TTKEPVFIPRPGITYEPPNYKALDFSEAP------SFTQPLVNRSVIAGYTAMLCCAVRG 1206
T KA+D AP +F Q V R AG + L A +G
Sbjct: 21970 VTG---------------TIKAVDRLTAPELDIDANFKQTHVVR---AGASIRLFIAYQG 22011
Query: 1207 SPKPKISWFKNGLDLGEDARFRMFSKQGVLTLE 1239
P P W K +L A LT+E
Sbjct: 22012 RPTPTAVWSKPDSNLSLRADIHTTDSFSTLTVE 22044
Score = 63.5 bits (153), Expect = 1e-09
Identities = 98/435 (22%), Positives = 159/435 (36%), Gaps = 53/435 (12%)
Query: 844 MRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDG 903
++ ++V + + RP P + P + V VS + L W P+ G +
Sbjct: 22356 VKTFSVTVVVIGRPGPVTGP------------IEVSSVSAESCVLSWGEPKDGGGTEITN 22403
Query: 904 YSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAG-----PGAPVTT 958
Y VE G + W + + T I V L FRV + N G AP+
Sbjct: 22404 YIVEKRESGTTAW-QLVNSSVKRTQIKVTHLTKYMEYSFRVSSENRFGVSKPLESAPIIA 22462
Query: 959 TEPVTVQEILQRPRLQLPRHLRQTI--QKKVGEPVNLLIPF--QGKPRPQVTWTKEGQPL 1014
P RP + +I ++ + + +I + + K R + W KE +
Sbjct: 22463 EHPFVPPSAPTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVP 22522
Query: 1015 AGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRV 1074
E T + + R ++ V + + + VD P P+ V
Sbjct: 22523 CLE---CNYKVTGLVEGLEYQFRTYA-LNAAGVSKASEASRPIMAQNPVDAPGRPE---V 22575
Query: 1075 TDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTM---EW----FTVLEHYRRTHCVVP 1127
TD V+L W P G +++ GY +++ + W +T++ T +
Sbjct: 22576 TDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALS 22635
Query: 1128 ELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPL 1187
E G+ Y FRV ++N G + + + PV Y PP + LD
Sbjct: 22636 E---GDTYEFRVLAKNAAGVISKGSESTGPVTCRDE---YAPPKAE-LDARLHGDLV--- 22685
Query: 1188 VNRSVIAGYTAMLCCAVRGSPKPKISWFKNG--LDLGEDARFRMFSKQGVLTLEIRKPCP 1245
++ AG +L AV G P+PKI W K LDL E + K+ T I+
Sbjct: 22686 ---TIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRA--TAVIKFCDR 22740
Query: 1246 FDGGIYVCRATNLQG 1260
D G Y N G
Sbjct: 22741 SDSGKYTLTVKNASG 22755
Score = 63.2 bits (152), Expect = 2e-09
Identities = 81/335 (24%), Positives = 134/335 (40%), Gaps = 41/335 (12%)
Query: 950 AGPG---APVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVT 1006
AGPG AP T+PV VQ++++ G V G P+P V
Sbjct: 1028 AGPGEPAAPYFITKPV-VQKLVE------------------GGSVVFGCQVGGNPKPHVY 1068
Query: 1007 WTKEGQPLAGE---EVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVV 1063
W K G PL +VS + L I +G Y + VR ++ E A+ L
Sbjct: 1069 WKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEE 1128
Query: 1064 DKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKK-TMEWFTVLEHYRRT 1122
+ + V + P+ VG T G+ + +K+ E + + +
Sbjct: 1129 ADYELLMKSQQEMLYQTQVTAFVQEPK-VGETAP-GFVYSEYEKEYEKEQALIRKKMAKD 1186
Query: 1123 HCVVPELIIGNGYYFRVFSQNMVGFSDRAA--TTKEPVFIPRPGITYEPPNYKALDFSEA 1180
VV + ++ F + ++ + TT E + + + A+D SE+
Sbjct: 1187 TVVVRTYVEDQEFHISSFEERLIKEIEYRIIKTTLEEL------LEEDGEEKMAVDISES 1240
Query: 1181 PS----FTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRM-FSKQGV 1235
+ F + N ++ G C + G P PKI+W+K+G + R++M F + G
Sbjct: 1241 EAVESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGR 1300
Query: 1236 LTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
+L I P D GIY A+N++G A C +L V
Sbjct: 1301 ASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYV 1335
Score = 62.4 bits (150), Expect = 3e-09
Identities = 65/275 (23%), Positives = 104/275 (37%), Gaps = 65/275 (23%)
Query: 1032 IRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQD 1091
++A +V G Y + ++N + P PP D+ V + + + WKPP
Sbjct: 8181 VKAVNKVGGGEY---IELKN----PVIAQDPKQPPDPPVDVEVHNPTAEAMTITWKPPLY 8233
Query: 1092 VGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELII-------GNGYYFRVFSQNM 1144
G +++ GY ++K K W EH +VP L G Y FRV ++N
Sbjct: 8234 DGGSKIMGYIIEKIAKGEERWKRCNEH------LVPILTYTAKGLEEGKEYQFRVRAENA 8287
Query: 1145 VGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAV 1204
G S+ + T P KA+D +AP + V G L ++
Sbjct: 8288 AGISEPSRAT---------------PPTKAVDPIDAPKVILR-TSLEVKRGDEIALDASI 8331
Query: 1205 RGSPKPKISWFKN-GLDLGEDARFRMF----------------------------SKQGV 1235
GSP P I+W K+ + + E+ + R SK+G
Sbjct: 8332 SGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGE 8391
Query: 1236 LTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
L +R D G+Y+ + N G A+ C + V
Sbjct: 8392 SQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSV 8426
Score = 60.5 bits (145), Expect = 1e-08
Identities = 55/197 (27%), Positives = 95/197 (48%), Gaps = 10/197 (5%)
Query: 451 EPPVLITRPLEDQLVMVGQRVEFECEV-SEEGAQVKWLKDGVELTREETFKYRFKKDGQR 509
E P + R ++ Q V G F V + + +W K+GV++ R + + + +D
Sbjct: 2030 EAPKIFER-IQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNV- 2087
Query: 510 HHLIINEAMLEDAGHY---ALCTSG-GQALAELIVQEKKLEVY-QSIADLMVGAKD-QAV 563
L+I + ED+ A+ +G + A L+VQ K+L + Q + D++ KD A
Sbjct: 2088 CELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMAT 2147
Query: 564 FKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFV-PEGFA 622
F+CE S+ V+ W K+G E+ + ++ +VH L+I + +D DYS V E
Sbjct: 2148 FECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDEN 2207
Query: 623 CNLSAKLHFMEVKIDFV 639
+AKL ++FV
Sbjct: 2208 VKTTAKLIVEGAVVEFV 2224
Score = 59.7 bits (143), Expect = 2e-08
Identities = 28/95 (29%), Positives = 46/95 (48%)
Query: 1176 DFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGV 1235
+ S+AP+F ++++ G + C + G P P+I WFKN L + + + + V
Sbjct: 26757 ELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNV 26816
Query: 1236 LTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
+LEIR D G Y +A N +G+ L V
Sbjct: 26817 YSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 26851
Score = 59.3 bits (142), Expect = 2e-08
Identities = 84/343 (24%), Positives = 125/343 (36%), Gaps = 68/343 (19%)
Query: 441 EKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEV-SEEGAQVKWLKDGVELTREETF 499
E S + F + IT + V GQ F V S+ A+VKW +GVEL +E+
Sbjct: 25989 EVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVEL--QESS 26046
Query: 500 KYRFKKDGQRHHLIINEAMLEDAGHY-ALCTS-GGQALAELIVQEKKLEVYQSIADLMVG 557
K + L I + +D+G Y A+CT+ G+A A L V
Sbjct: 26047 KIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEA--------------SDYATLDVT 26092
Query: 558 AKDQAVFKCEVSDENV-RGVWLKNGKELVPDSRIKVSHIGRVHKLTIDD--------VTP 608
D + + DE V R V+ EL VS + ++ +T
Sbjct: 26093 GGDYTTYASQRRDEEVPRSVF----PELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTE 26148
Query: 609 ADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRI---PDTIVVVAGN 665
E+ S+ A SA L ++ R KI RI P ++ V G
Sbjct: 26149 TRESLSSYEHSASAEMKSAALEEKSLEEKSTTR----KIKTTLAARILTKPRSMTVYEGE 26204
Query: 666 KLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRV 725
R G+P PTV W + K + T R
Sbjct: 26205 SARFSCDTDGEPVPTVTWLR-----------------------------KGQVLSTSARH 26235
Query: 726 RVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKV 768
+V TTK +S F + + DEG Y+V V+N G+ + T+ +
Sbjct: 26236 QVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTI 26278
Score = 58.5 bits (140), Expect = 4e-08
Identities = 76/315 (24%), Positives = 118/315 (37%), Gaps = 29/315 (9%)
Query: 981 QTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLA-GEEVSIRNSPTDTILFIRAARRVH 1039
Q + + G+P G+P+P+++W KE Q L+ G + + + L + A
Sbjct: 3200 QPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPED 3259
Query: 1040 SGTYQVTVRIEN--MEDKATLVLQVVDKPSPPQDLRVTDAWGLN-----VALEWKPPQ-- 1090
+ Y + + A+L ++V + SP Q++ V + V E +P +
Sbjct: 3260 AAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQ 3319
Query: 1091 -DVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGY-----YFRVFSQNM 1144
V T+L K K F + + T+ +L I Y + + N
Sbjct: 3320 CRVSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTY----QLEIAEAYPEDEGTYTFVASNA 3375
Query: 1145 VGFSDRAATTKEPVFIPRPGITYEPPNYKALDFS-------EAPSFTQPLVNRSVIAGYT 1197
VG A F T + +L S + PSF QPL + V G T
Sbjct: 3376 VGQVSSTANLSLEGFSKFEENTSNSQWHVSLSVSFKKEPLGQKPSFIQPLSSLRVHNGET 3435
Query: 1198 AMLCCAVRGSPKPKISWFKNGLDL--GEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRA 1255
V G PKP+I WF N + +D F G+ + I G Y C+A
Sbjct: 3436 VRFHARVSGIPKPEIQWFHNQQLILPTKDVVFHFEESTGMALMLIVDAYSEHAGQYSCKA 3495
Query: 1256 TNLQGEARCECRLEV 1270
N GEA C L V
Sbjct: 3496 ANSAGEATCAATLTV 3510
Score = 57.0 bits (136), Expect = 1e-07
Identities = 69/305 (22%), Positives = 116/305 (38%), Gaps = 26/305 (8%)
Query: 976 PRHLRQTIQKKVGEPVNLLIPFQ--GKPRPQVTWTKEGQPLA-GEEVSIRNSPTDTILFI 1032
P + Q + + E N+L + G+P P++ W K P++ VSI S L I
Sbjct: 26762 PAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEI 26821
Query: 1033 RAARRVHSGTYQVTVRIENMEDKAT---LVLQVVDKPSPPQDLRVTDAWGLNVALEWKPP 1089
R A SG Y + + + AT +VL +V++PS LR + L + +
Sbjct: 26822 RNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQGSFSSQSV 26881
Query: 1090 Q-DVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFS 1148
Q E + + +M ++ + E + + S + +G S
Sbjct: 26882 QMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFV------EMSSSSFMGIS 26935
Query: 1149 DRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSP 1208
+ + + GI PP +AL PS + S+ G + CA G P
Sbjct: 26936 NMTQLESSTSKMLKAGIRGIPPKIEAL-----PS------DISIDEGKVLTVACAFTGEP 26984
Query: 1209 KPKISWFKNG--LDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCEC 1266
P+++W G + E RF + + + TL I DGG+Y N G
Sbjct: 26985 TPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATV 27044
Query: 1267 RLEVR 1271
+ +R
Sbjct: 27045 NIHIR 27049
Score = 54.7 bits (130), Expect = 6e-07
Identities = 27/94 (28%), Positives = 44/94 (46%)
Query: 1181 PSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEI 1240
P+ L N +VI G + L C + G P P ++W++ + F++ + G+ L I
Sbjct: 897 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMI 956
Query: 1241 RKPCPFDGGIYVCRATNLQGEARCECRLEVRVPQ 1274
R+ D G + C A N G C L V+V +
Sbjct: 957 REAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSE 990
Score = 54.7 bits (130), Expect = 6e-07
Identities = 28/94 (29%), Positives = 45/94 (47%)
Query: 1180 APSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLE 1239
AP + + V G+ A C ++ +P + WFK G ++ E + + S + + +LE
Sbjct: 4461 APVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLE 4520
Query: 1240 IRKPCPFDGGIYVCRATNLQGEARCECRLEVRVP 1273
I + D G Y C+A+N G C L V VP
Sbjct: 4521 ILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVP 4554
Score = 54.7 bits (130), Expect = 6e-07
Identities = 24/85 (28%), Positives = 44/85 (51%)
Query: 12 FSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREV 71
F KP+++E+ G A F + V+W+R + + +KY + +G + L V++
Sbjct: 6182 FISKPQNLEILEGEKAEFVCSISKESFPVQWKRDDKTLESGDKYDVIADGKKRVLVVKDA 6241
Query: 72 GPADQGSYAVIAGSSKVKFDLKVIE 96
D G+Y V+ G+++ L VIE
Sbjct: 6242 TLQDMGTYVVMVGAARAAAHLTVIE 6266
Score = 54.3 bits (129), Expect = 7e-07
Identities = 31/96 (32%), Positives = 42/96 (43%)
Query: 1179 EAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTL 1238
E P Q L +V +G A C + G P+PKISW+K L + + TL
Sbjct: 3191 EPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTL 3250
Query: 1239 EIRKPCPFDGGIYVCRATNLQGEARCECRLEVRVPQ 1274
+ + P D +Y C A N G A L V VP+
Sbjct: 3251 LLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPE 3286
Score = 54.3 bits (129), Expect = 7e-07
Identities = 111/523 (21%), Positives = 174/523 (33%), Gaps = 88/523 (16%)
Query: 316 PAEEDVWEILRQAPPSEYERIAFQYGVTDLRGMLKRLKGMRRD-------EKKSTAFQKK 368
PAEE + R++P E R V+ R + + + R D K + QK
Sbjct: 25924 PAEEYEDDTERRSPTPERTRPRSPSPVSSERSLSRFERSARFDIFSRYESMKAALKTQKT 25983
Query: 369 LEPAYQV------SKGHKIRLTVELADH------------------DAEVKWLKNGQEIQ 404
E Y+V + H R+T+ + H AEVKW NG E+Q
Sbjct: 25984 SERKYEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQ 26043
Query: 405 MSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCSTELFV--------------- 449
S SK + + TL I C D Y+ V K +
Sbjct: 26044 ES-SKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQ 26102
Query: 450 ---KEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKKD 506
+E P + L + E+ E + V+ +K + TRE Y
Sbjct: 26103 RRDEEVPRSVFPELTRTEAYAVSSFKKTSEM-EASSSVREVKSQMTETRESLSSYEHSAS 26161
Query: 507 GQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFKC 566
+ + E LE+ + A ++ + + + VY+ + A F C
Sbjct: 26162 AEMKSAALEEKSLEEKSTTRKIKT--TLAARILTKPRSMTVYEG---------ESARFSC 26210
Query: 567 EVSDENVRGV-WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNL 625
+ E V V WL+ G+ L +R +V+ I V +DE +YS V E
Sbjct: 26211 DTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQ 26270
Query: 626 SA-------KLHFMEVKIDFVPRQEPPKIHLDCPGRI--PDTIVVVAGNKLRLDVPISGD 676
A K E + PR + P+ + P + P + + + P
Sbjct: 26271 EAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETK 26330
Query: 677 PAPT-------VIWQKAITQGNKAPARP-------APDAPEDTGDSDEWVFDKKLLCETE 722
P PT V ITQ KA A ++ W D K L E
Sbjct: 26331 PTPTEKVQHLPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKE-N 26389
Query: 723 GRVRVETTKDRSI-FTVEGAEKEDEGVYTVTVKNPVGEDQVNL 764
G + + D + + + D+G Y + G + NL
Sbjct: 26390 GHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNL 26432
Score = 53.1 bits (126), Expect = 2e-06
Identities = 31/104 (29%), Positives = 46/104 (44%)
Query: 1167 YEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDAR 1226
YE + + AP T + + V G V+ P ++ W+ NG++L E ++
Sbjct: 25988 YEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSK 26047
Query: 1227 FRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
+ GVLTLEI D G Y TN +GEA L+V
Sbjct: 26048 IHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDV 26091
Score = 52.8 bits (125), Expect = 2e-06
Identities = 28/90 (31%), Positives = 42/90 (46%)
Query: 6 KKPVSAFSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHT 65
K+P F+K V G+ AV E E R KV+W + G++I S KY + +G
Sbjct: 5909 KEPPVEFTKPLEDQTVEEGATAVLECEVSRENAKVKWFKNGTEILKSKKYEIVADGRVRK 5968
Query: 66 LTVREVGPADQGSYAVIAGSSKVKFDLKVI 95
L + + P D +Y A K +L V+
Sbjct: 5969 LVIHDCTPEDIKTYTCDAKDFKTSCNLNVV 5998
Score = 52.4 bits (124), Expect = 3e-06
Identities = 52/164 (31%), Positives = 74/164 (45%), Gaps = 17/164 (10%)
Query: 378 GHKIRLTVELADH-DAEVKWLKNGQEIQMSGS--KYIFESIGAKRTLTISQCSLADDAAY 434
G +R V + H + V W K+GQ+I+ + KY FES LTI+ + DDA Y
Sbjct: 25332 GENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEY 25391
Query: 435 QCVV----GGEKCSTELFV--KEPPVLIT-RPLEDQLV-----MVGQRVEFECEVSE-EG 481
V G + C +L V PP T RP+ +L+ GQ V FE VS
Sbjct: 25392 TVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPP 25451
Query: 482 AQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHY 525
+KW KDG L+ + + + L I + + ED G+Y
Sbjct: 25452 PTLKWEKDGQPLSLGPNIEI-IHEGLDYYALHIRDTLPEDTGYY 25494
Score = 52.0 bits (123), Expect = 4e-06
Identities = 26/86 (30%), Positives = 45/86 (52%)
Query: 14 KKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGP 73
+ P+ + A G+ VF AE + V+V+W R + +K+ + +EG H L + ++ P
Sbjct: 6544 RPPQDILEAPGADVVFLAELNKDKVEVQWLRNNMVVVQGDKHQMMSEGKIHRLQICDIKP 6603
Query: 74 ADQGSYAVIAGSSKVKFDLKVIEAEK 99
DQG Y IA + + L++ A K
Sbjct: 6604 RDQGEYRFIAKDKEARAKLELAAAPK 6629
Score = 50.8 bits (120), Expect = 8e-06
Identities = 51/207 (24%), Positives = 78/207 (37%), Gaps = 17/207 (8%)
Query: 1055 KATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGY-TVQKADKKTMEWF 1113
K L + +P PP+ L VT+ + L W PP G ++ GY T + +++ + +
Sbjct: 12416 KPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRW 12475
Query: 1114 TVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYK 1173
T + VV L G Y FRV ++N VG S +PR Y+
Sbjct: 12476 TEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVS-----------LPREAEGV----YE 12520
Query: 1174 ALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQ 1233
A + P P ++ AG + V G P P W K ++ + +
Sbjct: 12521 AKEQLLPPKILMP-EQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKAD 12579
Query: 1234 GVLTLEIRKPCPFDGGIYVCRATNLQG 1260
L I+ D G Y A N G
Sbjct: 12580 SSSILIIKDVTRKDSGYYSLTAENSSG 12606
Score = 50.4 bits (119), Expect = 1e-05
Identities = 22/81 (27%), Positives = 39/81 (48%)
Query: 17 RSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQ 76
+ +E F + R V ++W + G ++ N+ + +H LT+++ G D+
Sbjct: 6369 KDIETMEKKSVTFWCKVNRLNVTLKWTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGFPDE 6428
Query: 77 GSYAVIAGSSKVKFDLKVIEA 97
G Y V AG K +L +IEA
Sbjct: 6429 GEYIVTAGQDKSVAELLIIEA 6449
Score = 50.1 bits (118), Expect = 1e-05
Identities = 53/164 (32%), Positives = 80/164 (48%), Gaps = 20/164 (12%)
Query: 393 EVKWLKNGQEIQMS---GSKYIFESIGAKRTLTISQCSLADDAAYQCVV---GGEKCST- 445
EV W ++GQ I S G + F AK LTI + A+ Y G+ ST
Sbjct: 36 EVSWFRDGQVISTSTLPGVQISFSDGRAK--LTIPAVTKANSGRYSLKATNGSGQATSTA 93
Query: 446 ELFVKE---PPVLITRPLEDQLVMVGQRVEFECEVSEEGAQV-KWLKDGVELTREETFKY 501
EL VK PP + R L+ V G +V + V+ V K+ +DG E+ + + +
Sbjct: 94 ELLVKAETAPPNFVQR-LQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEI--QSSLDF 150
Query: 502 RFKKDGQRHHLIINEAMLEDAGHYAL--CTSGGQA--LAELIVQ 541
+ ++G + L+I EA ED+G Y++ S G+A AEL+VQ
Sbjct: 151 QISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194
Score = 49.7 bits (117), Expect = 2e-05
Identities = 54/228 (23%), Positives = 83/228 (36%), Gaps = 35/228 (15%)
Query: 1058 LVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLE 1117
L + + P+ P+ L T+ + L+WK P+ G + + GY ++K ++ E
Sbjct: 8915 LAVDPLGPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDF----E 8970
Query: 1118 HYRRTHCVVPELIIGN-----GYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNY 1172
+ C ++ N Y FRV + N +G S+ + P N
Sbjct: 8971 RVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSL----------------PLNV 9014
Query: 1173 KALDFSEAPSFTQPLVNRS----VIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFR 1228
D P+ L R V AG + V G P PKI W KN + +
Sbjct: 9015 VIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDAL 9074
Query: 1229 MFSKQGV------LTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
+K+ V L I K D G Y A+N G +EV
Sbjct: 9075 QITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEV 9122
Score = 49.7 bits (117), Expect = 2e-05
Identities = 24/94 (25%), Positives = 40/94 (42%)
Query: 1178 SEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLT 1237
S P L + +V + A G P+P W K+G + + ++++ +G
Sbjct: 26477 SSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFF 26536
Query: 1238 LEIRKPCPFDGGIYVCRATNLQGEARCECRLEVR 1271
LEI K D G+Y C N G C+L ++
Sbjct: 26537 LEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIK 26570
Score = 48.5 bits (114), Expect = 4e-05
Identities = 24/81 (29%), Positives = 37/81 (45%)
Query: 14 KKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGP 73
KKP+ V + FE V V+W +I S+K+ L +E H L ++ + P
Sbjct: 2753 KKPKDVTALENATVAFEVSVSHDTVPVKWFHKSVEIKPSDKHRLVSERKVHKLMLQNISP 2812
Query: 74 ADQGSYAVIAGSSKVKFDLKV 94
+D G Y + G + K L V
Sbjct: 2813 SDAGEYTAVVGQLECKAKLFV 2833
Score = 48.1 bits (113), Expect = 5e-05
Identities = 30/96 (31%), Positives = 47/96 (48%), Gaps = 2/96 (2%)
Query: 1178 SEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDA--RFRMFSKQGV 1235
++AP+FTQPL + V+ G TA + G P P++SWF++G + ++ G
Sbjct: 3 TQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGR 62
Query: 1236 LTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVR 1271
L I + G Y +ATN G+A L V+
Sbjct: 63 AKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98
Score = 48.1 bits (113), Expect = 5e-05
Identities = 54/233 (23%), Positives = 91/233 (39%), Gaps = 50/233 (21%)
Query: 545 LEVYQSIADLMVGAKD----QAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHK 600
L+ + I D+++ + A+F+C VS W+K+G + + + G+ K
Sbjct: 4743 LKFVKEIKDIILTESEFVGSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIADGKDRK 4802
Query: 601 LTIDDVTPADEADYSFVPE--GFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDT 658
L I DV +D +Y+ V +AKL E+ + FV E +
Sbjct: 4803 LHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEELPVRFVKTLE-------------EE 4849
Query: 659 IVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLL 718
+ VV G L L ++ + V+W+K D K++
Sbjct: 4850 VTVVKGQPLYLSCELNKE--RDVVWRK----------------------------DGKIV 4879
Query: 719 CETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDV 771
E GR+ T+ A+ D G YTVTV+N + + VKV++V
Sbjct: 4880 VEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVEN-ANNLECSSCVKVVEV 4931
Score = 47.8 bits (112), Expect = 7e-05
Identities = 31/102 (30%), Positives = 44/102 (43%)
Query: 1169 PPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFR 1228
P + + P F + + N + G A L V G PKPKI WF NG+ L A ++
Sbjct: 3570 PTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYK 3629
Query: 1229 MFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
+L I D G Y C A+N G+ C L++
Sbjct: 3630 FVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKI 3671
Score = 47.8 bits (112), Expect = 7e-05
Identities = 26/93 (27%), Positives = 41/93 (44%), Gaps = 3/93 (3%)
Query: 1181 PSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDL---GEDARFRMFSKQGVLT 1237
P FT PL N++ G + P+P ++W+K+G + D ++ S +G+
Sbjct: 25318 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQ 25377
Query: 1238 LEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
L I D Y A N GE C+ +L V
Sbjct: 25378 LTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV 25410
Score = 47.0 bits (110), Expect = 1e-04
Identities = 27/91 (29%), Positives = 40/91 (43%), Gaps = 1/91 (1%)
Query: 1181 PSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMF-SKQGVLTLE 1239
P F + L G A+ V G P P ++WFK L + + + G T
Sbjct: 3700 PHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFI 3759
Query: 1240 IRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
+ P D G+Y+C+A N+ GE+ C L V
Sbjct: 3760 VNDPQREDSGLYICKAENMLGESTCAAELLV 3790
Score = 45.8 bits (107), Expect = 3e-04
Identities = 22/82 (26%), Positives = 35/82 (42%)
Query: 13 SKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVG 72
+K +++EV A FE E V W + G +I S K+ + +G H L +
Sbjct: 2839 TKTMKNIEVPETKTASFECEVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTS 2898
Query: 73 PADQGSYAVIAGSSKVKFDLKV 94
D Y + G+ +V L V
Sbjct: 2899 TEDSAEYTFVCGNDQVSATLTV 2920
Score = 45.1 bits (105), Expect = 4e-04
Identities = 27/80 (33%), Positives = 37/80 (46%)
Query: 17 RSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQ 76
+ V V AG A F+ E + V W G + S+K +EG HTLT+R+V D
Sbjct: 5831 KDVTVTAGETATFDCELSYEDIPVEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLEDA 5890
Query: 77 GSYAVIAGSSKVKFDLKVIE 96
G + A K +L V E
Sbjct: 5891 GEVQLTAKDFKTHANLFVKE 5910
Score = 45.1 bits (105), Expect = 4e-04
Identities = 29/91 (31%), Positives = 44/91 (48%), Gaps = 5/91 (5%)
Query: 1183 FTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRK 1242
FT+PL +++V G TA+L C V K+ WFKNG ++ + ++ + + V L I
Sbjct: 5915 FTKPLEDQTVEEGATAVLECEV-SRENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHD 5973
Query: 1243 PCPFDGGIYVCRATNLQGEARCECRLEVRVP 1273
P D Y C A + + C L V P
Sbjct: 5974 CTPEDIKTYTCDAKDF----KTSCNLNVVPP 6000
Score = 44.7 bits (104), Expect = 6e-04
Identities = 33/108 (30%), Positives = 43/108 (39%), Gaps = 6/108 (5%)
Query: 1165 ITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNG--LDLG 1222
+T PP D + P F + L N G + V G P P + W K+G L LG
Sbjct: 25410 VTLHPP---PTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLG 25466
Query: 1223 EDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
+ + L IR P D G Y ATN G C+ L+V
Sbjct: 25467 PNIEI-IHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQV 25513
Score = 44.7 bits (104), Expect = 6e-04
Identities = 48/223 (21%), Positives = 85/223 (38%), Gaps = 8/223 (3%)
Query: 558 AKDQAVFKCEVSDENVRG---VWLKNGKELVPDSRIKVSHIGR-VHKLTIDDVTPADEAD 613
+K+ A C V +R W K+GK+L + + + ++L I+++T +D+ +
Sbjct: 26357 SKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGE 26416
Query: 614 YSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPI 673
Y G L FM + + + V + + PI
Sbjct: 26417 YVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPI 26476
Query: 674 SGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDR 733
S P V + T + + A+ A A + + W D K + + G+ ++ K
Sbjct: 26477 SSKPV-IVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQG-GKYKLSEDKGG 26534
Query: 734 SIFTVEGAEKEDEGVYTVTVKNPVG--EDQVNLTVKVIDVPDA 774
+ + D G+YT TVKN G LT+K I +A
Sbjct: 26535 FFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEA 26577
Score = 44.3 bits (103), Expect = 8e-04
Identities = 26/91 (28%), Positives = 43/91 (47%)
Query: 1181 PSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEI 1240
P+F Q L + +V G L V G P P + ++++G ++ F++ + + +L I
Sbjct: 104 PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLI 163
Query: 1241 RKPCPFDGGIYVCRATNLQGEARCECRLEVR 1271
+ P D G Y ATN G A L V+
Sbjct: 164 AEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194
Score = 44.3 bits (103), Expect = 8e-04
Identities = 29/108 (26%), Positives = 49/108 (45%), Gaps = 16/108 (14%)
Query: 10 SAFSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVR 69
+ F+K ++EV+ E + G +V W +G +I + +Y + TEG + L ++
Sbjct: 6091 AVFTKNLANIEVSETDTIKLVCEVSKPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQ 6150
Query: 70 EVGPADQGSYAVIAGSS----KVKF------------DLKVIEAEKAE 101
D G+Y SS KVK +L+++E EKAE
Sbjct: 6151 NAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLEILEGEKAE 6198
Score = 43.5 bits (101), Expect = 0.001
Identities = 23/76 (30%), Positives = 35/76 (46%)
Query: 28 VFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYAVIAGSSK 87
VFE E +G+ V W +I S+KY + G + LTV + D+G Y AG +
Sbjct: 2505 VFEVELSHSGIDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTFYAGENM 2564
Query: 88 VKFDLKVIEAEKAEPM 103
L V ++P+
Sbjct: 2565 TSGKLTVAGGAISKPL 2580
Score = 43.1 bits (100), Expect = 0.002
Identities = 45/174 (25%), Positives = 72/174 (41%), Gaps = 10/174 (5%)
Query: 449 VKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKKDGQ 508
+KE +I PL D + G V ++ +V W + + +E FK +D
Sbjct: 4363 IKEDGPMIHTPLVDTVSEEGDIVHLTTSITN-AKEVNWYFENKLVPSDEKFKCL--QDQN 4419
Query: 509 RHHLIINEAMLED-AGHY---ALCTSGGQALAELIVQEKKLE--VYQSIADLMVGAKDQA 562
+ L+I++ ED G Y AL SG A + + K+ + + I L V A
Sbjct: 4420 TYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLA 4479
Query: 563 VFKCEV-SDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYS 615
F CE+ S NVR W K G+E+ + + + L I D +Y+
Sbjct: 4480 KFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYT 4533
Score = 42.0 bits (97), Expect = 0.004
Identities = 33/111 (29%), Positives = 51/111 (45%), Gaps = 14/111 (12%)
Query: 453 PVLITRPLEDQLVMVGQRVEFECEVS-EEGAQVKWLKDGVELTREETFKYRFKKDGQRHH 511
P IT+P+ +LV G V F C+V V W K GV LT +K + K
Sbjct: 1036 PYFITKPVVQKLVEGGS-VVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECK 1094
Query: 512 LIINEAMLEDAGHYALC-------TSGGQALA-----ELIVQEKKLEVYQS 550
L+I+ +DAG Y + TS +L EL+++ ++ +YQ+
Sbjct: 1095 LVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLMKSQQEMLYQT 1145
Score = 41.6 bits (96), Expect = 0.005
Identities = 21/86 (24%), Positives = 38/86 (44%)
Query: 9 VSAFSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTV 68
V F K+ + +EV E ++ +W ++ ++ KY + + R LTV
Sbjct: 2220 VVEFVKELQDIEVPESYSGELECIVSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTV 2279
Query: 69 REVGPADQGSYAVIAGSSKVKFDLKV 94
++V DQG Y+ + K LK+
Sbjct: 2280 KDVTKEDQGEYSFVIDGKKTTCKLKM 2305
Score = 41.2 bits (95), Expect = 0.006
Identities = 23/105 (21%), Positives = 46/105 (43%), Gaps = 16/105 (15%)
Query: 12 FSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREV 71
F K + ++V A+FE E + V+W + ++ +++ + E H L +
Sbjct: 3014 FRKHIKDIKVLEKKRAMFECEVSEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPST 3073
Query: 72 GPADQGSYAVIAGSS----------------KVKFDLKVIEAEKA 100
+D G Y V+AG + +K +++VIE ++A
Sbjct: 3074 RMSDAGKYTVVAGGNVSTAKLFVEGRDVRIRSIKKEVQVIEKQRA 3118
Score = 41.2 bits (95), Expect = 0.006
Identities = 23/91 (25%), Positives = 41/91 (45%)
Query: 8 PVSAFSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLT 67
P F + ++V A FE E R KV+W + G++I KY + ++G L
Sbjct: 6000 PHVEFLRPLTDLQVREKEMARFECELSRENAKVKWFKDGAEIKKGKKYDIISKGAVRILV 6059
Query: 68 VREVGPADQGSYAVIAGSSKVKFDLKVIEAE 98
+ + D+ Y+ +++ L V+E E
Sbjct: 6060 INKCLLDDEAEYSCEVRTARTSGMLTVLEEE 6090
Score = 40.8 bits (94), Expect = 0.008
Identities = 38/167 (22%), Positives = 69/167 (41%), Gaps = 8/167 (4%)
Query: 457 TRPLEDQLVMVGQRVEFECEVSE-EGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIIN 515
T+PL+ +V+ G FE +S +V W +DG ++ + R L I
Sbjct: 9 TQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIP 68
Query: 516 EAMLEDAGHYALCTSGGQ----ALAELIVQEKKL--EVYQSIADLMVGAKDQAVFKCEVS 569
++G Y+L + G + AEL+V+ + Q + + V Q + V+
Sbjct: 69 AVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVT 128
Query: 570 DENVRGV-WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYS 615
V + ++G E+ ++S G ++ L I + P D YS
Sbjct: 129 GIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYS 175
Score = 40.8 bits (94), Expect = 0.008
Identities = 21/70 (30%), Positives = 36/70 (51%), Gaps = 1/70 (1%)
Query: 27 AVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYA-VIAGS 85
A FE ET VKV+W + G ++ +KY + ++ H L++ + +D Y+ V+
Sbjct: 2146 ATFECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVED 2205
Query: 86 SKVKFDLKVI 95
VK K+I
Sbjct: 2206 ENVKTTAKLI 2215
Score = 40.8 bits (94), Expect = 0.008
Identities = 29/105 (27%), Positives = 44/105 (41%), Gaps = 9/105 (8%)
Query: 27 AVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYA--VIAG 84
AVF + R V+W R G +I KY +G+ H L +++ D+ YA V
Sbjct: 6468 AVFSCQLSREKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDCRLDDECEYACGVEDR 6527
Query: 85 SSKVKFDLKVIEAEKAEPMLAPAPAPAEATGAPGEAPAPAAELGE 129
S+ + ++ I E P P + APG AEL +
Sbjct: 6528 KSRARLFVEEIPVEIIRP-------PQDILEAPGADVVFLAELNK 6565
Score = 40.8 bits (94), Expect = 0.008
Identities = 24/80 (30%), Positives = 38/80 (47%), Gaps = 1/80 (1%)
Query: 40 VRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYAVIAGSSKVKFDLKVIEAEK 99
++W R G ++ S KY ++++G HTLTV D+G Y IA + + + +
Sbjct: 24192 IKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQ 24251
Query: 100 AEPMLAPA-PAPAEATGAPG 118
A P P P + GA G
Sbjct: 24252 ATPQFHPGYPLKEKYYGAVG 24271
Score = 40.8 bits (94), Expect = 0.008
Identities = 69/326 (21%), Positives = 130/326 (39%), Gaps = 64/326 (19%)
Query: 478 SEEGAQVKWLKDGVELTREE---TFKYR------FKKDGQRHHLIINEAMLEDAGHYALC 528
+ E Q WLK +E + T K+R KKD +++++ A + G A+
Sbjct: 25124 ASEALQHPWLKQKIERVSTKVIRTLKHRRYYHTLIKKD---LNMVVSAARISCGG--AIR 25178
Query: 529 TSGGQALAELIVQEKKL-----EVYQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKE 583
+ G ++A++ V ++ ++ ++ + G + V K E D++ + W ++
Sbjct: 25179 SQKGVSVAKVKVASIEIGPVSGQIMHAVGE--EGGHVKYVCKIENYDQSTQVTWYFGVRQ 25236
Query: 584 LVPDSRIKVSHIGRVHKLTIDDVTPADEADY--SFVPEGFACNLSAKLHFMEVK--IDFV 639
L + ++++ V L + D+T D+ Y V + + A+L V+ D+
Sbjct: 25237 LENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFVKGVREVYDYY 25296
Query: 640 PRQEPPKIH--------LDCPGRIPDTI---VVVAGNKLRLDVPISGDPAPTVIWQKAIT 688
R+ KI L+ P + G +R V I+ P P V W K+
Sbjct: 25297 CRRTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKS-- 25354
Query: 689 QGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGV 748
G K +P + + T +SD+ ++ T+ +D+
Sbjct: 25355 -GQKI--KPGDNDKKYTFESDKGLYQ---------------------LTINSVTTDDDAE 25390
Query: 749 YTVTVKNPVGED--QVNLTVKVIDVP 772
YTV +N GED + LTV + P
Sbjct: 25391 YTVVARNKYGEDSCKAKLTVTLHPPP 25416
Score = 40.4 bits (93), Expect = 0.011
Identities = 18/57 (31%), Positives = 30/57 (52%)
Query: 38 VKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYAVIAGSSKVKFDLKV 94
V V+W + G +I S KY + +G R L +++ D+G Y G+ K K ++ V
Sbjct: 5318 VPVKWFKDGEEIVPSPKYSIKADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTV 5374
Score = 40.4 bits (93), Expect = 0.011
Identities = 17/61 (27%), Positives = 31/61 (50%)
Query: 19 VEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGS 78
V+V A FE E R RW +G +I+ +++ L +GT+H++ ++ D+
Sbjct: 5477 VKVFEKDEAKFECEVSREPKTFRWLKGTQEITGDDRFELIKDGTKHSMVIKSAAFEDEAK 5536
Query: 79 Y 79
Y
Sbjct: 5537 Y 5537
Score = 39.7 bits (91), Expect = 0.019
Identities = 46/199 (23%), Positives = 87/199 (43%), Gaps = 20/199 (10%)
Query: 453 PVLITRPLEDQLVMVGQRVEFECEV-SEEGAQVKWLKDGVELTREETFKYRFKKDGQRHH 511
PV + +P+ + + GQ F+ +V + W DG ++ + T K K+DG +
Sbjct: 1411 PVFVLKPVSFKC-LEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQ-S 1468
Query: 512 LIINEAMLEDAGHYALCT---SGGQALAELI-VQEKKLEVYQSIADLM--VGAKDQAVFK 565
LII A D+G + + +G +++ ++ V+ + +V + + V K+ + +
Sbjct: 1469 LIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLE 1528
Query: 566 CEV---SDENVRGVWLKNGKELVPDS--RIKVSHIGRVHKLTIDDVTPADEADYSFVPEG 620
+V + N VWLKN +VP +I++ L ID D A Y+
Sbjct: 1529 MKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAIN 1588
Query: 621 FA------CNLSAKLHFME 633
A C ++ ++ F E
Sbjct: 1589 KAGRDTTRCKVNVEVEFAE 1607
Score = 39.3 bits (90), Expect = 0.024
Identities = 29/94 (30%), Positives = 37/94 (39%), Gaps = 1/94 (1%)
Query: 11 AFSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVRE 70
A SK VA AVFE E K W R G + +N ++G + L +
Sbjct: 2575 AISKPLTDQTVAESQEAVFECEVANPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAA 2634
Query: 71 VGPADQGSYAVIAGSSKVKFDLKVIEAEKAEPML 104
D G Y +SK LKV EA K + L
Sbjct: 2635 TKLDDIGEYTYKVATSKTSAKLKV-EAVKIKKTL 2667
Score = 39.3 bits (90), Expect = 0.024
Identities = 22/88 (25%), Positives = 41/88 (46%), Gaps = 16/88 (18%)
Query: 29 FEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYAVIAGSS-- 86
FE G+ +W + G +I +++K + T+ H+L +R V D Y +AG +
Sbjct: 2942 FEVTVNYEGISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKATS 3001
Query: 87 ---------KVKF-----DLKVIEAEKA 100
++F D+KV+E ++A
Sbjct: 3002 TATLYVEARHIEFRKHIKDIKVLEKKRA 3029
Score = 38.5 bits (88), Expect = 0.041
Identities = 22/81 (27%), Positives = 35/81 (43%)
Query: 1191 SVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGI 1250
+V G +A C G P P ++W + G L AR ++ + + T EI D G
Sbjct: 26199 TVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGN 26258
Query: 1251 YVCRATNLQGEARCECRLEVR 1271
Y N +G+ E L ++
Sbjct: 26259 YSVVVENSEGKQEAEFTLTIQ 26279
Score = 37.7 bits (86), Expect = 0.071
Identities = 30/109 (27%), Positives = 43/109 (39%), Gaps = 1/109 (0%)
Query: 1163 PGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLG 1222
PG E + L+ P F V+ + G TA V G P P+ WF +G +
Sbjct: 1393 PGRRLEETDESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIV 1452
Query: 1223 EDARFRMFSKQ-GVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
D ++ K+ G +L I P D G + A N G + L V
Sbjct: 1453 NDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTV 1501
Score = 37.0 bits (84), Expect = 0.12
Identities = 44/219 (20%), Positives = 72/219 (32%), Gaps = 44/219 (20%)
Query: 577 WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEG----FACNLSAKLH-- 630
W NG L P + K G H L I DE +Y+ + C+ K++
Sbjct: 3615 WFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSK 3674
Query: 631 ---FMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVA---GNKLRLDVPISGDPAPTVIWQ 684
+ + + + K+ CP + + G + + G+PAPTV W
Sbjct: 3675 GEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWF 3734
Query: 685 KAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKE 744
K + K LC + + F V ++E
Sbjct: 3735 K----------------------------ENKQLCTSVYYTIIHNPNGSGTFIVNDPQRE 3766
Query: 745 DEGVYTVTVKNPVGEDQVNLTVKVI----DVPDAPAAPK 779
D G+Y +N +GE + V+ D+ D P K
Sbjct: 3767 DSGLYICKAENMLGESTCAAELLVLLEDTDMTDTPCKAK 3805
Score = 36.6 bits (83), Expect = 0.16
Identities = 20/71 (28%), Positives = 33/71 (46%), Gaps = 3/71 (4%)
Query: 456 ITRPLEDQLVMVGQRVEFECE-VSEEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLII 514
I + ++D +G+ + C+ V +KW + G EL + KY+ DG+ H L +
Sbjct: 24163 IRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSR--KYKMSSDGRTHTLTV 24220
Query: 515 NEAMLEDAGHY 525
ED G Y
Sbjct: 24221 MTEEQEDEGVY 24231
Score = 36.6 bits (83), Expect = 0.16
Identities = 27/92 (29%), Positives = 42/92 (45%), Gaps = 5/92 (5%)
Query: 1175 LDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSP--KPKISWFKNGLDLGEDARFRM-FS 1231
L S P TQ L ++ + A L C V S +++W+K+G L E+ F+ +S
Sbjct: 26340 LPVSAPPKITQFL--KAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYS 26397
Query: 1232 KQGVLTLEIRKPCPFDGGIYVCRATNLQGEAR 1263
G L+I D G YVC + G ++
Sbjct: 26398 ADGTYELKINNLTESDQGEYVCEISGEGGTSK 26429
Score = 36.2 bits (82), Expect = 0.21
Identities = 20/79 (25%), Positives = 34/79 (43%), Gaps = 1/79 (1%)
Query: 17 RSVEVAAGSPAVFEAETERAGV-KVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPAD 75
+ V V G+ AV E + V V+W I ++ +GT+ L + +D
Sbjct: 2406 KDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHASD 2465
Query: 76 QGSYAVIAGSSKVKFDLKV 94
+G Y +I G + +L V
Sbjct: 2466 EGPYKLIVGRVETNCNLSV 2484
Score = 36.2 bits (82), Expect = 0.21
Identities = 55/274 (20%), Positives = 91/274 (33%), Gaps = 66/274 (24%)
Query: 17 RSVEVAAGSPAVFEAETERAGVKVRWQRGGSDIS--ASNKYGLATEGTRHTLTVREVGPA 74
+ V+V AV E E V W + G +I+ ++ E H + + E +
Sbjct: 3108 KEVQVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQS 3167
Query: 75 DQGSYAVIAGSSKVKFDLKVIEAE------KAEPMLAPAPAPAEATGAPGEAPAPAAE-- 126
D G Y +AG ++ L V E + +P+ + PA P P
Sbjct: 3168 DAGEYTFVAGRNRSSVTLYVNAPEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWY 3227
Query: 127 ------------------------LGESAPSPKG---------------SSSAALNGPTP 147
L E+ P S+S ++ P
Sbjct: 3228 KEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEV 3287
Query: 148 GAPDDPIGLF---VMRP-QDGEVTVGGSITFSARVAGASLLKPPVVKWFKGKWVDLSSKV 203
+PD + ++ ++ P QD + G F RV+G L V W+ S+
Sbjct: 3288 VSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDL----KVSWYSKDKKIKPSRF 3343
Query: 204 GQHLQLHDSYDRASKVYLFELHITDAQPAFTGSY 237
+ Q D+Y +L I +A P G+Y
Sbjct: 3344 FRMTQFEDTY---------QLEIAEAYPEDEGTY 3368
Score = 35.8 bits (81), Expect = 0.27
Identities = 19/72 (26%), Positives = 35/72 (48%), Gaps = 1/72 (1%)
Query: 14 KKPRSVEVAAGSPAVFEAETERAGVK-VRWQRGGSDISASNKYGLATEGTRHTLTVREVG 72
K +++ V AVF E VK V+W + G + ++ KY ++ +GT ++L ++
Sbjct: 2665 KTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYSLRIKNCA 2724
Query: 73 PADQGSYAVIAG 84
D+ Y G
Sbjct: 2725 IVDESVYGFRLG 2736
Score = 35.8 bits (81), Expect = 0.27
Identities = 23/78 (29%), Positives = 35/78 (44%)
Query: 19 VEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGS 78
VEV G A FE E V +W+ G ++AS + +G +H L + G
Sbjct: 5388 VEVFVGETAHFEIELSEPDVHGQWKLKGQPLTASPDCEIIEDGKKHILILHNCQLGMTGE 5447
Query: 79 YAVIAGSSKVKFDLKVIE 96
+ A ++K +LKV E
Sbjct: 5448 VSFQAANAKSAANLKVKE 5465
Score = 35.8 bits (81), Expect = 0.27
Identities = 18/78 (23%), Positives = 36/78 (46%), Gaps = 2/78 (2%)
Query: 28 VFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYAVIAGSSK 87
+ + E +A V+W + G +I S + +G + L +++ +D G Y G+ K
Sbjct: 5664 ILQCEISKADAPVKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTCDCGTDK 5723
Query: 88 V--KFDLKVIEAEKAEPM 103
K D++ E + P+
Sbjct: 5724 TSGKLDIEDREIKLVRPL 5741
Score = 35.8 bits (81), Expect = 0.27
Identities = 27/118 (22%), Positives = 50/118 (42%), Gaps = 19/118 (16%)
Query: 577 WLKNGKELVP---DSRIKVSHIGRVHKLTIDDVTPADEADYSFVP------EGFACNLSA 627
W K+G+++ P D + +++LTI+ VT D+A+Y+ V + L+
Sbjct: 25351 WYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV 25410
Query: 628 KLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQK 685
LH P + + +C G + ++ +SG P PT+ W+K
Sbjct: 25411 TLHPPPTDSTLRPMFKRLLANAECQ----------EGQSVCFEIRVSGIPPPTLKWEK 25458
Score = 35.4 bits (80), Expect = 0.35
Identities = 16/47 (34%), Positives = 30/47 (63%)
Query: 40 VRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYAVIAGSS 86
V++ R G++I +S + ++ EG ++L + E P D G+Y+V A +S
Sbjct: 135 VKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNS 181
Score = 35.4 bits (80), Expect = 0.35
Identities = 45/203 (22%), Positives = 72/203 (35%), Gaps = 60/203 (29%)
Query: 40 VRWQRGGSDISASN---KYGLATEGTRHTLTVREVGPADQGSYAVIAGSSKVKFDLKVIE 96
V W + G I + KY ++ + LT+ V D Y V+A + + +
Sbjct: 25349 VTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGE------D 25402
Query: 97 AEKAEPMLAPAPAPAEATGAPGEAPAPAAELGESAPSPKGSSSAALNGPTPGAPDDPIGL 156
+ KA+ + P P ++T P +
Sbjct: 25403 SCKAKLTVTLHPPPTDSTLRP--------------------------------------M 25424
Query: 157 FVMRPQDGEVTVGGSITFSARVAGASLLKPPVVKWFK-GKWVDLSSKVGQHLQLHDSYDR 215
F + E G S+ F RV+G + PP +KW K G+ + L + +H+ D
Sbjct: 25425 FKRLLANAECQEGQSVCFEIRVSG---IPPPTLKWEKDGQPLSLGPNIEI---IHEGLD- 25477
Query: 216 ASKVYLFELHITDAQPAFTGSYR 238
+ LHI D P TG YR
Sbjct: 25478 -----YYALHIRDTLPEDTGYYR 25495
Score = 35.0 bits (79), Expect = 0.46
Identities = 19/65 (29%), Positives = 28/65 (43%)
Query: 17 RSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQ 76
+ V VF E G K +W R I S+KY + + +TL +R+ DQ
Sbjct: 6275 KDTRVKEQQEVVFNCEVNTEGAKAKWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLDDQ 6334
Query: 77 GSYAV 81
+Y V
Sbjct: 6335 ANYNV 6339
Score = 34.7 bits (78), Expect = 0.60
Identities = 19/48 (39%), Positives = 25/48 (52%), Gaps = 2/48 (4%)
Query: 483 QVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTS 530
+++W +GV LT +K+ F DG H LII LED G Y S
Sbjct: 3612 KIQWFFNGVLLTPSADYKFVF--DGDDHSLIILFTKLEDEGEYTCMAS 3657
Score = 34.3 bits (77), Expect = 0.78
Identities = 20/85 (23%), Positives = 36/85 (42%), Gaps = 9/85 (10%)
Query: 5 GKKPVSAFSKKPRSVEVAAG--SPAVFEAETERAGVKVR-------WQRGGSDISASNKY 55
GKK KPR + + G V E + + VKV W + G ++ S++
Sbjct: 2296 GKKTTCKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRV 2355
Query: 56 GLATEGTRHTLTVREVGPADQGSYA 80
+ + H L + ++ D G+Y+
Sbjct: 2356 HIVIDKQSHMLLIEDMTKEDAGNYS 2380
Score = 34.3 bits (77), Expect = 0.78
Identities = 42/222 (18%), Positives = 84/222 (37%), Gaps = 41/222 (18%)
Query: 24 GSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYAVIA 83
G PA F+ +KV W I S + + + L + E P D+G+Y +A
Sbjct: 3313 GQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVA 3372
Query: 84 GSSKVKFDLKVIEAEKAEPMLAPAPAPAEATGAPGEAPAPAAELGESAPSPKGSSSAALN 143
+ A + + + ++ E+ + + S +++
Sbjct: 3373 SN-----------------------AVGQVSSTANLSLEGFSKFEENTSNSQWHVSLSVS 3409
Query: 144 GPTPGAPDDPIG---LFVMRPQDGEVTVGGSITFSARVAGASLLKPPVVKWFKGKWVDLS 200
+P+G F+ V G ++ F ARV+G + P ++WF + + L
Sbjct: 3410 -----FKKEPLGQKPSFIQPLSSLRVHNGETVRFHARVSG---IPKPEIQWFHNQQLILP 3461
Query: 201 SKVGQHLQLHDSYDRASKVYLFELHITDAQPAFTGSYRCEVS 242
+K + H ++ ++ + L + I DA G Y C+ +
Sbjct: 3462 TK---DVVFH--FEESTGMAL--MLIVDAYSEHAGQYSCKAA 3496
Score = 34.3 bits (77), Expect = 0.78
Identities = 24/87 (27%), Positives = 42/87 (48%), Gaps = 4/87 (4%)
Query: 1179 EAPS-FTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLT 1237
EAP+ F + L +++V A+ C + K + W++NG ++ E +++ F K G +
Sbjct: 6448 EAPTEFVEHLEDQTVTEFDDAVFSCQL-SREKANVKWYRNGREIKEGKKYK-FEKDGSIH 6505
Query: 1238 LEIRKPCPFDGGI-YVCRATNLQGEAR 1263
I K C D Y C + + AR
Sbjct: 6506 RLIIKDCRLDDECEYACGVEDRKSRAR 6532
Score = 34.3 bits (77), Expect = 0.78
Identities = 20/65 (30%), Positives = 33/65 (50%), Gaps = 5/65 (7%)
Query: 393 EVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCV----VGGEKCSTELF 448
++KW + G+E+ S KY S G TLT+ D+ Y C+ VG + S++L
Sbjct: 24191 DIKWYRFGKELIQS-RKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLL 24249
Query: 449 VKEPP 453
++ P
Sbjct: 24250 LQATP 24254
Score = 33.9 bits (76), Expect = 1.0
Identities = 17/59 (28%), Positives = 27/59 (45%)
Query: 24 GSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYAVI 82
GS A+FE + W + GS+I S K+ +G L + +V +D G Y +
Sbjct: 4761 GSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYTCV 4819
Score = 33.5 bits (75), Expect = 1.3
Identities = 25/125 (20%), Positives = 50/125 (40%), Gaps = 7/125 (5%)
Query: 16 PRSVEVAAGSPAVFEAETE-RAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPA 74
P + + AG EA + +W++G ++ S+ + + L +++V
Sbjct: 12533 PEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRK 12592
Query: 75 DQGSYAVIAGSSKVKFDLKVIEAEKAEPMLAPAPAPAEATGAPGEAPAPAAELGESAPSP 134
D G Y++ A +S + +K + ++ AP P + + A A L P
Sbjct: 12593 DSGYYSLTAENS------SGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSLSWHIPLE 12646
Query: 135 KGSSS 139
G S+
Sbjct: 12647 DGGSN 12651
Score = 33.1 bits (74), Expect = 1.7
Identities = 53/201 (26%), Positives = 74/201 (36%), Gaps = 44/201 (21%)
Query: 87 KVKFDLKVIEAEKAEPMLAP--APAPAEATGAPGEAPAPAAELGE----------SAPSP 134
K + ++K I+ EP P AP G EA AP E + PSP
Sbjct: 4652 KPEAEVKTIKPPPVEPEPTPIAAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPSP 4711
Query: 135 KGSSSAALNGPTPGA--PDD----------PIGLFVMRPQDGEVT----VGGSITFSARV 178
+ L + G PD+ P+ FV +D +T VG S F V
Sbjct: 4712 IEAERRKLRPGSGGEKPPDEAPFTYQLKAVPLK-FVKEIKDIILTESEFVGSSAIFECLV 4770
Query: 179 AGASLLKPPVVKWFK-GKWVDLSSKVGQHLQLHDSYDRASKVYLFELHITDAQPAFTGSY 237
+ ++ + W K G + S K H + D DR +LHI D Q + G Y
Sbjct: 4771 SPSTA----ITTWMKDGSNIRESPK---HRFIADGKDR-------KLHIIDVQLSDAGEY 4816
Query: 238 RCEVSTKDKFDCSNFNLTVHE 258
C + +K S L V E
Sbjct: 4817 TCVLRLGNKEKTSTAKLVVEE 4837
Score = 33.1 bits (74), Expect = 1.7
Identities = 16/72 (22%), Positives = 31/72 (43%)
Query: 27 AVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYAVIAGSS 86
AVF E ++V+W + + + + EG H++T +++ D V A
Sbjct: 5574 AVFTVELSHDNIRVKWFKNDQRLHTTRSVSMQDEGKTHSITFKDLSIDDTSQIRVEAMGM 5633
Query: 87 KVKFDLKVIEAE 98
+ L V+E +
Sbjct: 5634 SSEAKLTVLEGD 5645
Score = 33.1 bits (74), Expect = 1.7
Identities = 21/84 (25%), Positives = 38/84 (45%), Gaps = 5/84 (5%)
Query: 19 VEVAAGSPAVFEAETE-RAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQG 77
V + AGS V +A + K+ W +G ++ K L G R T ++ +D G
Sbjct: 22685 VTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSG 22744
Query: 78 SYAV----IAGSSKVKFDLKVIEA 97
Y + +G+ V +KV+++
Sbjct: 22745 KYTLTVKNASGTKAVSVMVKVLDS 22768
Score = 32.7 bits (73), Expect = 2.3
Identities = 21/72 (29%), Positives = 35/72 (48%), Gaps = 2/72 (2%)
Query: 460 LEDQLVMVGQRVEFECEVSEEGA-QVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAM 518
+++ ++ G V F C++S ++ W KDG + E ++ F +DG R L I +
Sbjct: 1251 IKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDG-RASLRIPVVL 1309
Query: 519 LEDAGHYALCTS 530
ED G Y S
Sbjct: 1310 PEDEGIYTAFAS 1321
Score = 32.3 bits (72), Expect = 3.0
Identities = 43/171 (25%), Positives = 67/171 (39%), Gaps = 22/171 (12%)
Query: 948 NMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQT--IQKKVGEPVNLLIPFQGKPRPQV 1005
N G G T TE + + + P L++ I+ G P G+P P V
Sbjct: 3672 NSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTV 3731
Query: 1006 TWTKEGQPL-AGEEVSIRNSPTDTILFI-RAARRVHSGTYQVTVRIENMEDKAT------ 1057
TW KE + L +I ++P + FI +R SG Y + ENM ++T
Sbjct: 3732 TWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLY--ICKAENMLGESTCAAELL 3789
Query: 1058 LVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKK 1108
++L+ D P + T + P+D T L G V+ D +
Sbjct: 3790 VLLEDTDMTDTPCKAKSTP----------EAPEDFPQTPLKGPAVEALDSE 3830
Score = 32.3 bits (72), Expect = 3.0
Identities = 22/83 (26%), Positives = 34/83 (40%), Gaps = 1/83 (1%)
Query: 12 FSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREV 71
F+ + V V A FE R V W +G I +S+K+ + +G +H L + +
Sbjct: 5116 FAVPLKDVTVPERRQARFECVLTREA-NVIWSKGPDIIKSSDKFDIIADGKKHILVINDS 5174
Query: 72 GPADQGSYAVIAGSSKVKFDLKV 94
D+G Y K L V
Sbjct: 5175 QFDDEGVYTAEVEGKKTSARLFV 5197
Score = 32.3 bits (72), Expect = 3.0
Identities = 24/67 (35%), Positives = 30/67 (44%), Gaps = 5/67 (7%)
Query: 467 VGQRVEFECEVSEEG---AQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAG 523
V R + + +V +G A V W KDG L +ET + L I EA ED G
Sbjct: 19034 VKAREQLKIDVPFKGRPQATVNWRKDGQTL--KETTRVNVSSSKTVTSLSIKEASKEDVG 19091
Query: 524 HYALCTS 530
Y LC S
Sbjct: 19092 TYELCVS 19098
Score = 32.0 bits (71), Expect = 3.9
Identities = 21/81 (25%), Positives = 35/81 (43%), Gaps = 1/81 (1%)
Query: 6 KKPVSAFSKKPRSVEVAAGSPAVFEAETERA-GVKVRWQRGGSDISASNKYGLATEGTRH 64
K+ +K +EVA G A F E + A V+ +W + G +I S+K + +
Sbjct: 4458 KRAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYIS 4517
Query: 65 TLTVREVGPADQGSYAVIAGS 85
+L + D G Y A +
Sbjct: 4518 SLEILRTQVVDCGEYTCKASN 4538
Score = 32.0 bits (71), Expect = 3.9
Identities = 22/76 (28%), Positives = 33/76 (43%), Gaps = 1/76 (1%)
Query: 1179 EAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTL 1238
E FT+ L N V T L C V P ++ W+K ++ E R+ + ++ L
Sbjct: 6089 EEAVFTKNLANIEVSETDTIKLVCEV-SKPGAEVIWYKGDEEIIETGRYEILTEGRKRIL 6147
Query: 1239 EIRKPCPFDGGIYVCR 1254
I+ D G Y CR
Sbjct: 6148 VIQNAHLEDAGNYNCR 6163
Score = 32.0 bits (71), Expect = 3.9
Identities = 22/61 (36%), Positives = 30/61 (49%), Gaps = 2/61 (3%)
Query: 988 GEPVNLLIPFQGKPRPQVTWTKEGQPLA-GEEVSIRNSPTD-TILFIRAARRVHSGTYQV 1045
G+ V I G P P + W K+GQPL+ G + I + D L IR +G Y+V
Sbjct: 25437 GQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRV 25496
Query: 1046 T 1046
T
Sbjct: 25497 T 25497
Score = 31.6 bits (70), Expect = 5.1
Identities = 23/81 (28%), Positives = 33/81 (40%), Gaps = 5/81 (6%)
Query: 21 VAAGSPAVFEAETERAGVKV-RWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSY 79
V AG+ F A V +W GS+I Y + T+ LT++ D G Y
Sbjct: 11150 VKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEY 11209
Query: 80 AV----IAGSSKVKFDLKVIE 96
+ AGS V L V++
Sbjct: 11210 QITVSNAAGSKTVAVHLTVLD 11230
Score = 31.6 bits (70), Expect = 5.1
Identities = 25/107 (23%), Positives = 43/107 (40%), Gaps = 11/107 (10%)
Query: 18 SVEVAAGSPAVFEAETERAGVK-VRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQ 76
++ V AG EA+ + + W RG +I S + + + L V++ D
Sbjct: 17262 TIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDG 17321
Query: 77 GSYAV----IAGSSKVKFDLKVIEAEKAEPMLAPAPAPAEATGAPGE 119
G Y + +AGS ++KV++ P P + TG E
Sbjct: 17322 GQYILRASNVAGSKSFPVNVKVLDRP------GPPEGPVQVTGVTSE 17362
Score = 31.6 bits (70), Expect = 5.1
Identities = 32/96 (33%), Positives = 42/96 (43%), Gaps = 18/96 (18%)
Query: 988 GEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDT----ILFIRAARRVHSGTY 1043
GE G+P P VTW ++GQ L+ S R+ T T I + + G Y
Sbjct: 26203 GESARFSCDTDGEPVPTVTWLRKGQVLS---TSARHQVTTTKYKSTFEISSVQASDEGNY 26259
Query: 1044 QVTVRIENMEDKA----TLVLQ---VVDK--PSPPQ 1070
V V EN E K TL +Q V +K SPP+
Sbjct: 26260 SVVV--ENSEGKQEAEFTLTIQKARVTEKAVTSPPR 26293
Score = 31.2 bits (69), Expect = 6.6
Identities = 20/71 (28%), Positives = 31/71 (43%), Gaps = 1/71 (1%)
Query: 1183 FTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRK 1242
F +PL + V A C + K+ WFK+G ++ + ++ + SK V L I K
Sbjct: 6004 FLRPLTDLQVREKEMARFECEL-SRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINK 6062
Query: 1243 PCPFDGGIYVC 1253
D Y C
Sbjct: 6063 CLLDDEAEYSC 6073
Score = 31.2 bits (69), Expect = 6.6
Identities = 43/175 (24%), Positives = 71/175 (40%), Gaps = 15/175 (8%)
Query: 379 HKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRT-LTISQCSLADDAAYQCV 437
+ + L+ E +HD + L E+Q GS K T TI+ ++ +++
Sbjct: 15691 NSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATCATVKVTEATITGLIQGEEYSFRVS 15750
Query: 438 VGGEKCSTELFVKEPPV----LITRPLEDQL-----VMVGQRVEFECE-VSEEGAQVKWL 487
EK ++ PV L+ P L V+ G+ ++ + + V W
Sbjct: 15751 AQNEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWH 15810
Query: 488 KDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYA--LCTSGGQALAELIV 540
KD V L ++T + + L I +A ED GHY L S G+A+ L V
Sbjct: 15811 KDNVPL--KQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNV 15863
Score = 31.2 bits (69), Expect = 6.6
Identities = 23/87 (26%), Positives = 39/87 (44%), Gaps = 3/87 (3%)
Query: 23 AGSPAVFEAETE-RAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSY-A 80
AGSP + R KV W+ + +++ + T R TLTV++ D G Y
Sbjct: 22289 AGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFL 22348
Query: 81 VIAGSSKVK-FDLKVIEAEKAEPMLAP 106
+ ++ VK F + V+ + P+ P
Sbjct: 22349 TLENTAGVKTFSVTVVVIGRPGPVTGP 22375
Score = 31.2 bits (69), Expect = 6.6
Identities = 31/113 (27%), Positives = 44/113 (38%), Gaps = 8/113 (7%)
Query: 963 TVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPL-AGEEVSI 1021
T++ + + P LP + + VGE V + P P VTW K GQ + G+
Sbjct: 25310 TMRLLERPPEFTLPLYNKTAY---VGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKK 25366
Query: 1022 RNSPTDTILF---IRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQD 1071
+D L+ I + Y V R + ED L V P PP D
Sbjct: 25367 YTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHP-PPTD 25418
Score = 30.8 bits (68), Expect = 8.6
Identities = 20/78 (25%), Positives = 31/78 (39%)
Query: 21 VAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYA 80
V G A F E + V W + + + S +++EG H L ++EV D
Sbjct: 5213 VKEGETATFVCELSHEKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQIK 5272
Query: 81 VIAGSSKVKFDLKVIEAE 98
LKV+EA+
Sbjct: 5273 AQVKELSSTAQLKVLEAD 5290
>gi|110349715 titin isoform N2-B [Homo sapiens]
Length = 26926
Score = 286 bits (732), Expect = 9e-77
Identities = 238/845 (28%), Positives = 366/845 (43%), Gaps = 77/845 (9%)
Query: 386 ELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCST 445
+L+ A VKW +NG+EI+ G KY FE G+ L I C L D+ Y C V K
Sbjct: 6348 QLSREKANVKWYRNGREIK-EGKKYKFEKDGSIHRLIIKDCRLDDECEYACGVEDRKSRA 6406
Query: 446 ELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKK 505
LFV+E PV I RP +D L G V F E++++ +V+WL++ + + + + K++
Sbjct: 6407 RLFVEEIPVEIIRPPQDILEAPGADVVFLAELNKDKVEVQWLRNNMVVVQGD--KHQMMS 6464
Query: 506 DGQRHHLIINEAMLEDAGHYALCTSGGQALAEL-IVQEKKLEVYQSIADLMVGAKDQAVF 564
+G+ H L I + D G Y +A A+L + K++ + VG V
Sbjct: 6465 EGKIHRLQICDIKPRDQGEYRFIAKDKEARAKLELAAAPKIKTADQDLVVDVGKPLTMVV 6524
Query: 565 KCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACN 624
+ + W K + L S + I + D+ Y V + N
Sbjct: 6525 PYDAYPK-AEAEWFKENEPL---STKTIDTTAEQTSFRILEAKKGDKGRYKIVLQ----N 6576
Query: 625 LSAKLH-FMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIW 683
K F+ +K+ +D PG + + L+V + D ++ W
Sbjct: 6577 KHGKAEGFINLKV------------IDVPGPVRN-----------LEVTETFDGEVSLAW 6613
Query: 684 QKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEK 743
++ +T G + + + D+ CE FTV G +K
Sbjct: 6614 EEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAESCE---------------FTVTGLQK 6658
Query: 744 ED-EGVYTVTVKNPVGEDQVNLTVKVI------DVPDAPAAPKISNVGEDSCTVQWEPPA 796
E ++ V+ +N VG + T + DVP P I++V ++ WEPP
Sbjct: 6659 GGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRFGVSLTWEPPE 6718
Query: 797 YDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSR 856
YDGG I Y++E + K S RW ++LS ++EG Y RV A N IG+ +
Sbjct: 6719 YDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGK 6778
Query: 857 PSPASQPFM----PIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEG 912
PS A+ PF+ PI PS P +L D + ++V LKW PP + G + GY +E C EG
Sbjct: 6779 PSAAT-PFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEG 6837
Query: 913 CSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPR 972
W+ L + V L G + L+RV A N AG P P+T + P
Sbjct: 6838 KDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPT 6897
Query: 973 LQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPL-AGEEVSIRNSPTDTILF 1031
+ L + ++ V P+ +L+P G PRP TW + L G+ V ++ L
Sbjct: 6898 MDLSA-FKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELV 6956
Query: 1032 IRAARRVHSGTYQVTVRIENMED--KATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPP 1089
I + R G Y T+++EN + + V+ +PS P++L+ D +V L W+PP
Sbjct: 6957 ISPSERSDKGIY--TLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHLTWEPP 7014
Query: 1090 QDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSD 1149
D G + L GY V+K + W V++ VP+L+ G Y F+V ++N G
Sbjct: 7015 DDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCG-PG 7073
Query: 1150 RAATTKEPVFIPRPGITYEPP-NYKALDFSEAPSFT--QPLVN--RSVIAGYTAMLCCAV 1204
A EPV + P +PP N K D + F P N S I GY C
Sbjct: 7074 EPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERC--P 7131
Query: 1205 RGSPK 1209
RGS K
Sbjct: 7132 RGSDK 7136
Score = 243 bits (619), Expect = 1e-63
Identities = 204/708 (28%), Positives = 303/708 (42%), Gaps = 81/708 (11%)
Query: 567 EVSDENVRGVWLKNGKELVPDSRIKVSHI--GRVHKLTIDDVTPADEADYSFVPEGFACN 624
+V DE R + E P+++ KV+ + G+ +K + V A E+D + VPE
Sbjct: 10656 KVGDEEWRRA--NHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVK 10713
Query: 625 LSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQ 684
R EPP++ LD I V G+ LRL I G P P V W+
Sbjct: 10714 ---------------DRLEPPELILDANMAREQHIKV--GDTLRLSAIIKGVPFPKVTWK 10756
Query: 685 KAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKE 744
K DAP + R++ T S + A E
Sbjct: 10757 KEDR-----------DAPT--------------------KARIDVTPVGSKLEIRNAAHE 10785
Query: 745 DEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPIL 804
D G+Y++TV+NP G V++ V V+D P P ++S + +DSC + W+ P DGG I
Sbjct: 10786 DGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVIT 10845
Query: 805 GYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMS------RPS 858
Y++ER+ S +W L+ ++ SH A+ + EG Y RV A N G +P
Sbjct: 10846 NYVVERRDVASAQWSPLS-ATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPI 10904
Query: 859 PASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVA 918
A P P GPP + H+ DV T VSL W P+R G + GY VEY EG +W+
Sbjct: 10905 KALDPLHPPGPPKDLHHV---DVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIK 10961
Query: 919 ALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRH 978
+ +V L G FRV+A N+ G G P TT P+ QE L P ++L
Sbjct: 10962 F--KTVTNLECVVTGLQQGKTYRFRVKAENIVGLGLP-DTTIPIECQEKLVPPSVELDVK 11018
Query: 979 LRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPL-AGEEVSIRNSPTDTILFIRAARR 1037
L + + K G V +G P P WT +G + E ++ ++L I+ R
Sbjct: 11019 LIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLR 11078
Query: 1038 VHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQ-DLRVTDAWGLNVALEWKPPQDVGNTE 1096
+G YQ+TV + L V+D P PP + + D ++ + W+PP+D G +
Sbjct: 11079 RDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTISWQPPKDDGGSP 11138
Query: 1097 LWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFS---DRAAT 1153
+ Y V+K D + W V +T +P L G Y FRV ++N +G D T
Sbjct: 11139 VINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPT 11198
Query: 1154 TKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVN-RSVIAGY------TAMLCCAVRG 1206
+ F P P +P + + S+T P + S I GY V
Sbjct: 11199 VAKHKFSP-PSPPGKPVVTDITENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVNK 11257
Query: 1207 SPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCR 1254
+P + + GL G FR+F++ + KP P I CR
Sbjct: 11258 TPIADLKFRVTGLYEGNTYEFRVFAEN---LAGLSKPSPSSDPIKACR 11302
Score = 238 bits (608), Expect = 2e-62
Identities = 190/681 (27%), Positives = 288/681 (42%), Gaps = 96/681 (14%)
Query: 344 DLRGMLKRLKGMRRDEKKSTAFQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEI 403
DLR +++ LK + EKKS F K+ RL V L KW KNG+E+
Sbjct: 6236 DLR-IVEPLKDIETMEKKSVTFWCKVN-----------RLNVTL-------KWTKNGEEV 6276
Query: 404 QMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCSTELFVKEPPVLITRPLEDQ 463
++ + K LTI C D+ Y G +K EL + E P LEDQ
Sbjct: 6277 PFD-NRVSYRVDKYKHMLTIKDCGFPDEGEYIVTAGQDKSVAELLIIEAPTEFVEHLEDQ 6335
Query: 464 LVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAG 523
V F C++S E A VKW ++G E+ +E KY+F+KDG H LII + L+D
Sbjct: 6336 TVTEFDDAVFSCQLSREKANVKWYRNGREI--KEGKKYKFEKDGSIHRLIIKDCRLDDEC 6393
Query: 524 HYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKE 583
YA ++ A L V+E +E+ + D++ VF E++ + V WL+N
Sbjct: 6394 EYACGVEDRKSRARLFVEEIPVEIIRPPQDILEAPGADVVFLAELNKDKVEVQWLRNNMV 6453
Query: 584 LVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQE 643
+V + ++ G++H+L I D+ P D+ +Y F+ AK K++
Sbjct: 6454 VVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFI---------AKDKEARAKLELA---A 6501
Query: 644 PPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPE 703
PKI +VV G L + VP P W K
Sbjct: 6502 APKIK-----TADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKE----------------- 6539
Query: 704 DTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVN 763
++ L +T ++TT +++ F + A+K D+G Y + ++N G+ +
Sbjct: 6540 ----------NEPLSTKT-----IDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGF 6584
Query: 764 LTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNF 823
+ +KVIDVP +++ + ++ WE P DGG I+GY++ER+ K W+ L
Sbjct: 6585 INLKVIDVPGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWV-LAT 6643
Query: 824 DLIQELSHEARRMIE-GVVYEMRVYAVNAIGMSRPSPASQPF---MPIGPPSEPTHLAVE 879
D + + + GV Y RV A N +G P P P P ++ +
Sbjct: 6644 DRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTIT 6703
Query: 880 DVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGAR 939
DV+ VSL W PPE G + Y +E + W A+ E S V D+ G
Sbjct: 6704 DVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQE 6763
Query: 940 LLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQG 999
FRVRA N G G P T V V + ++RP PVNL Q
Sbjct: 6764 YSFRVRAQNRIGVGKPSAATPFVKVADPIERP----------------SPPVNLTSSDQT 6807
Query: 1000 KPRPQVTWTKE----GQPLAG 1016
+ Q+ W G P+ G
Sbjct: 6808 QSSVQLKWEPPLKDGGSPILG 6828
Score = 236 bits (601), Expect = 1e-61
Identities = 159/530 (30%), Positives = 248/530 (46%), Gaps = 48/530 (9%)
Query: 641 RQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPD 700
R EPP+I LD R +V+ A LRL V I G P P V W+KA
Sbjct: 18604 RIEPPEIELDADLR--KVVVLRASATLRLFVTIKGRPEPEVKWEKA-------------- 18647
Query: 701 APEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGED 760
+ +L + R ++E T ++ ++ + D G Y +T++N G
Sbjct: 18648 --------------EGILTD---RAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSGSK 18690
Query: 761 QVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKK--KKSYRW 818
+ V+V+D P AP I V +DS T+ WEPP DGG I YI+E+++ +K+Y
Sbjct: 18691 TAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYAT 18750
Query: 819 MRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAV 878
+ N + + + EG Y RV A N G+ P+ ++P PP P + +
Sbjct: 18751 ITNN---CTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTL 18807
Query: 879 EDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGA 938
DV+ T ++KW PE G + GY VE +G +W Q T +I L G
Sbjct: 18808 VDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVKTLEATI--SGLTAGE 18865
Query: 939 RLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQ 998
+FRV A N G P PV ++I +P ++LP H T K E + + +PF+
Sbjct: 18866 EYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFH---TFNVKAREQLKIDVPFK 18922
Query: 999 GKPRPQVTWTKEGQPLAGE-EVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKAT 1057
G+P+ V W K+GQ L V++ +S T T L I+ A + GTY++ V
Sbjct: 18923 GRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVP 18982
Query: 1058 LVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLE 1117
+ + V+D+P PP +R+ + ++ + W PP+ G ++ Y V+K + + W V +
Sbjct: 18983 ITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQ 19042
Query: 1118 HYRRTHCVVPELIIGNGYYFRVFSQNMVG---FSDRAATTKEPVFIPRPG 1164
RT + L G+ Y FRV ++N G +S+ +A E F P PG
Sbjct: 19043 AVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSP-PG 19091
Score = 234 bits (596), Expect = 5e-61
Identities = 179/608 (29%), Positives = 272/608 (44%), Gaps = 59/608 (9%)
Query: 577 WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKI 636
W G +L R+ V +V KLTI + T D +Y+ + S +K+
Sbjct: 23275 WFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSET-----IKV 23329
Query: 637 DFVPRQEPPK--IHLDCPGRIPDTIVVVAGNKLRLD--VPISGDPAPTVIWQKAITQGNK 692
+ + PP I +D I T + ++ LD P+SG V+ Q+
Sbjct: 23330 IILDKPGPPTGPIKID---EIDATSITISWEPPELDGGAPLSG----YVVEQR------- 23375
Query: 693 APARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVT 752
DA G + V + RS F + +E V+ V
Sbjct: 23376 -------DA------------------HRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVA 23410
Query: 753 VKNPVG-----EDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYI 807
N G + +V I +P P +I +V D T+ W PP DGG + GYI
Sbjct: 23411 ATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYI 23470
Query: 808 LERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM-- 865
+ERK+ ++ RW+R+N + + + + EG+ YE RV A+NA G +PS S+P +
Sbjct: 23471 VERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAM 23530
Query: 866 -PIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLT 924
PI PP +P + V D + T+VSL W PE G + GY +E EW T
Sbjct: 23531 DPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPT 23590
Query: 925 EHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQ 984
+ + LP GA FRV A N GPG P V V E+L+ P +L ++ I
Sbjct: 23591 KIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGIF 23650
Query: 985 KKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQ 1044
+ G + L IP +GKP P WTKEGQ ++ + I S T T L I+ A R SGTY
Sbjct: 23651 VRQGGVIRLTIPIKGKPFPICKWTKEGQDIS-KRAMIATSETHTELVIKEADRGDSGTYD 23709
Query: 1045 VTVRIENMEDKATLVLQVVDKPSPPQ-DLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQ 1103
+ + + + + ++V+ P+ P+ L D +V + W+PP D G ++ GY ++
Sbjct: 23710 LVLENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILE 23769
Query: 1104 KADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRP 1163
+ + W+T+ R T VV L Y+FRV ++N G S + ++EPV P
Sbjct: 23770 RREVPKAAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAENQFGIS-KPLKSEEPVTPKTP 23828
Query: 1164 GITYEPPN 1171
EPP+
Sbjct: 23829 LNPPEPPS 23836
Score = 232 bits (591), Expect = 2e-60
Identities = 155/508 (30%), Positives = 236/508 (46%), Gaps = 43/508 (8%)
Query: 702 PEDTGDSD--EWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVG- 758
P+D G S +V +K+ + V V + +T+ + E V+ + +N G
Sbjct: 9744 PKDDGGSKITNYVIEKRE-ANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGI 9802
Query: 759 ----EDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKK 814
+ + + VP AP P +S+V +S TV WE P YDGG P+ GY LE K
Sbjct: 9803 GEPLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTT 9862
Query: 815 SYRWMRLNFDLIQEL----SHEARRMIEGVVYEMRVYAVNAIGM------SRPSPASQPF 864
S RW R+N D I+ + S++ +IEG Y+ RVYA+NA G+ S P+ A P
Sbjct: 9863 SKRWKRVNRDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPI 9922
Query: 865 MPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLT 924
P GPP V D + ++ L+W PP + G + GY VEY EG EW
Sbjct: 9923 APPGPPFPK----VTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEV 9978
Query: 925 EHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQ 984
T ++V L GA FRVRA N+AG G P T+ + +++ L P LQL +R I
Sbjct: 9979 RGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRDRIV 10038
Query: 985 KKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQ 1044
G + ++ GKP P VTW + L +E +I + + + I+ +R H G Y
Sbjct: 10039 VHAGGVIRIIAYVSGKPPPTVTWNMNERTLP-QEATIETTAISSSMVIKNCQRSHQGVYS 10097
Query: 1045 VTVRIENMEDKATLVLQVVDKPSP-PQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQ 1103
+ + E E K T+++ V+D P P + + L W P+D G + + Y ++
Sbjct: 10098 LLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIE 10157
Query: 1104 KADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGF-----SDRAATTKEPV 1158
K + W V R + V LI G Y+FR+ ++N +G + A +EP+
Sbjct: 10158 KRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPI 10217
Query: 1159 FIP-RP-------------GITYEPPNY 1172
+P RP +T+ PP Y
Sbjct: 10218 TVPERPEDLEVKEVTKNTVTLTWNPPKY 10245
Score = 232 bits (591), Expect = 2e-60
Identities = 161/590 (27%), Positives = 263/590 (44%), Gaps = 48/590 (8%)
Query: 643 EPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAP 702
E P++ LD + IVV AG R+ +P G P P + W +
Sbjct: 17523 EAPELDLD--SELRKGIVVRAGGSARIHIPFKGRPTPEITWSR----------------- 17563
Query: 703 EDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQV 762
+E F K V++E + + +++ ++ D G Y + ++N G
Sbjct: 17564 ------EEGEFTDK--------VQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSA 17609
Query: 763 NLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLN 822
+TVKV+D P P + V +DS + WEPP DGG + Y++++++ + ++
Sbjct: 17610 FVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRESTRKAYANVS 17669
Query: 823 FDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVS 882
+ S + + EG +Y RV A N G+ P PPS P + + DVS
Sbjct: 17670 -SKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEPPSPPGKVTLTDVS 17728
Query: 883 DTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLF 942
T+ SL W PE G + GY VE P+G +W ++ ++ + +V L +G F
Sbjct: 17729 QTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKW--SIVAESKVCNAVVTGLSSGQEYQF 17786
Query: 943 RVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPR 1002
RV+A+N G P PV +++ +P L+LP + T + GE + + IP G+PR
Sbjct: 17787 RVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFN---TYSIQAGEDLKIEIPVIGRPR 17843
Query: 1003 PQVTWTKEGQPL-AGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQ 1061
P ++W K+G+PL V++ + T T+L I+ + G Y VT L +
Sbjct: 17844 PNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVI 17903
Query: 1062 VVDKPSPP-QDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYR 1120
V++KP PP +R + V + W+PP G ++ Y V+K D T W V
Sbjct: 17904 VLEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATVA 17963
Query: 1121 RTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEA 1180
RT + +L G Y FR+F++N G S A + V + P ++ P F +
Sbjct: 17964 RTTIKITKLKTGTEYQFRIFAENRYGKS--APLDSKAVIVQYP---FKEPGPPGTPFVTS 18018
Query: 1181 PSFTQPLV--NRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFR 1228
S Q LV + V G T ++ + K I W K +D +F+
Sbjct: 18019 ISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFK 18068
Score = 231 bits (588), Expect = 4e-60
Identities = 175/602 (29%), Positives = 273/602 (45%), Gaps = 99/602 (16%)
Query: 643 EPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIW------------------- 683
EPP++ +D R D IVV AG L+++ I+G P P + W
Sbjct: 19288 EPPRVMMDVKFR--DVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTD 19345
Query: 684 ----------------QKAITQGNKAPAR-----------PAPDA--------------- 701
Q +T N A R P P A
Sbjct: 19346 NHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSL 19405
Query: 702 ----PEDTG--DSDEWVFDKK-------LLCETEGRVRVETTKDRSIFTVEGAEKEDEGV 748
P++ G D D ++ +K+ +CE G +++ + K + K +E +
Sbjct: 19406 SWGRPQEDGGADIDYYIVEKRETSHLAWTICE--GELQMTSCKVTKLL------KGNEYI 19457
Query: 749 YTVTVKNP--VGEDQVNLTVKVID---VPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPI 803
+ VT N VGE ++ +K +D VP P + +I++V ++S T+ W P DGG I
Sbjct: 19458 FRVTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEI 19517
Query: 804 LGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQP 863
GYI+ER++K S RW+R+N + +L ++ + EG YE RVYA NA G+S PS S
Sbjct: 19518 SGYIIERREKNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPL 19577
Query: 864 FM---PIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAAL 920
P+ PS P+ + D TT+++ W P G + GY+VEY ++W ++
Sbjct: 19578 IRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSI 19637
Query: 921 QGL--TEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRH 978
Q L TE+T + L TGA +FRV++ N G P +++P +E + P +
Sbjct: 19638 QSLRGTEYT---ISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSE 19694
Query: 979 LRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRV 1038
+R+T+ K G + +PF+G+P P V W+K L + + + T L I A R
Sbjct: 19695 MRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLR-TRAYVDTTDSRTSLTIENANRN 19753
Query: 1039 HSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELW 1098
SG Y +T++ TLV++V+D P PP ++ V D + L W P++ G +
Sbjct: 19754 DSGKYTLTIQNVLSAASLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDVPENDGGAPVK 19813
Query: 1099 GYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPV 1158
Y ++K + W +V + R V L G YYFRV +N G A TKE V
Sbjct: 19814 NYHIEKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVG-IPAETKEGV 19872
Query: 1159 FI 1160
I
Sbjct: 19873 KI 19874
Score = 230 bits (587), Expect = 6e-60
Identities = 151/532 (28%), Positives = 240/532 (45%), Gaps = 42/532 (7%)
Query: 641 RQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPD 700
R+E P +D R T++V AG + VP G P P V+W K PD
Sbjct: 19683 REEEPLFDIDSEMR--KTLIVKAGASFTMTVPFRGRPVPNVLWSK-------------PD 19727
Query: 701 APEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGED 760
T R V+TT R+ T+E A + D G YT+T++N +
Sbjct: 19728 TDLRT------------------RAYVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAA 19769
Query: 761 QVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMR 820
+ L VKV+D P P + +V ++S + W+ P DGG P+ Y +E+++ W+
Sbjct: 19770 SLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDVPENDGGAPVKNYHIEKREASKKAWVS 19829
Query: 821 LNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVED 880
+ + LS++ + EG +Y RV N G+ P+ + PS P L V
Sbjct: 19830 VTNNC-NRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGVKITEKPSPPEKLGVTS 19888
Query: 881 VSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARL 940
+S +VSL W PE G + Y VE +G WV + + T +V L +
Sbjct: 19889 ISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQKNWVKC--AVAKSTHHVVSGLRENSEY 19946
Query: 941 LFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGK 1000
FRV A N AG P PV ++E L+ P + + T+ + G + + IP GK
Sbjct: 19947 FFRVFAENQAGLSDPRELLLPVLIKEQLEPPEIDMKNFPSHTVYVRAGSNLKVDIPISGK 20006
Query: 1001 PRPQVTWTKEGQPL-AGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLV 1059
P P+VT +++G PL A + + + + ++ + +G Y++T + KA +
Sbjct: 20007 PLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFIN 20066
Query: 1060 LQVVDKPSPPQ-DLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEH 1118
+ V+D+P PP + ++D +V L+W+PP+ G +++ Y + K + T W V
Sbjct: 20067 IVVLDRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSAT 20126
Query: 1119 YRRTHCVVPELIIGNGYYFRVFSQNMVGFSDR----AATTKEPVFIPRPGIT 1166
RT V +L G Y FR+ ++N G SD T K P P P T
Sbjct: 20127 VARTMMKVMKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPST 20178
Score = 229 bits (585), Expect = 1e-59
Identities = 167/615 (27%), Positives = 275/615 (44%), Gaps = 63/615 (10%)
Query: 565 KCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACN 624
+CE +N W++ +LVP+ KV+ + + +K + V+ ++A S P
Sbjct: 6833 RCEEGKDN----WIRCNMKLVPELTYKVTGLEKGNKY-LYRVSAENKAGVSD-PSEILGP 6886
Query: 625 LSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQ 684
L+A F+E +D D + V+ N + + VP +G P PT W
Sbjct: 6887 LTADDAFVEPTMDL--------------SAFKDGLEVIVPNPITILVPSTGYPRPTATW- 6931
Query: 685 KAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKE 744
F K+L ET RV+++T + + +E+
Sbjct: 6932 ---------------------------CFGDKVL-ETGDRVKMKTLSAYAELVISPSERS 6963
Query: 745 DEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPIL 804
D+G+YT+ ++N V + V VI P AP K ++ +DS + WEPP DGG P+
Sbjct: 6964 DKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLT 7023
Query: 805 GYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPF 864
GY++E+++ W ++ D + +L +++G Y +V A N G P+ +P
Sbjct: 7024 GYVVEKREVSRKTWTKV-MDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPV 7082
Query: 865 ---MPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQ 921
P P P ++ D + ++ L W PP+ G + GY VE CP G +WVA +
Sbjct: 7083 NMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGE 7142
Query: 922 GLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQ 981
+ E T + V L G +RV+A N G P TE + + + P + L L
Sbjct: 7143 PVAE-TKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLA 7201
Query: 982 TIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEE-VSIRNSPTDTILFIRAARRVHS 1040
+ K G + L GKP P++TWTK L ++ ++I N P + + I ++R +
Sbjct: 7202 GLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDT 7261
Query: 1041 GTYQVTVRIENMEDKATLVLQ--VVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELW 1098
GTY + N+ +AT V++ V+DKP PP +TD + L W PP+D G +++
Sbjct: 7262 GTY--IIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKIT 7319
Query: 1099 GYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSD----RAATT 1154
Y V++ + W + + T+ +LI Y FRV ++NM G + T
Sbjct: 7320 NYVVERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITA 7379
Query: 1155 KEPVFIPRPGITYEP 1169
K P P EP
Sbjct: 7380 KYQFDPPGPPTRLEP 7394
Score = 225 bits (574), Expect = 2e-58
Identities = 166/609 (27%), Positives = 271/609 (44%), Gaps = 60/609 (9%)
Query: 643 EPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAP 702
E P I LD R I + AG LRL VPI G P P V W K
Sbjct: 16441 EAPDIDLDLELR--KIINIRAGGSLRLFVPIKGRPTPEVKWGKV---------------- 16482
Query: 703 EDTGDSDEWVFDKKLLCETEGRVR----VETTKDRSIFTVEGAEKEDEGVYTVTVKNPVG 758
+G +R ++ T + ++ + D G YT+T++N G
Sbjct: 16483 -------------------DGEIRDAAIIDVTSSFTSLVLDNVNRYDSGKYTLTLENSSG 16523
Query: 759 EDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKK--KKSY 816
+TV+V+D P P K++ + +DS ++ WEPP DGG I YI+E+++ +KSY
Sbjct: 16524 TKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEKREATRKSY 16583
Query: 817 RWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHL 876
+ N + S + ++ EG Y RV A N G+ P+ + P P P +
Sbjct: 16584 AAVVTN---CHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPPGKI 16640
Query: 877 AVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPT 936
V+DV+ +VSL W PE G + Y VE + +W + + ++ +L
Sbjct: 16641 TVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECAR--VKSLQAVITNLTQ 16698
Query: 937 GARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIP 996
G LFRV A N G P + P+ ++++ P ++ P ++Q VG+ + + +P
Sbjct: 16699 GEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVK-PAFSSYSVQ--VGQDLKIEVP 16755
Query: 997 FQGKPRPQVTWTKEGQPL-AGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDK 1055
G+P+P +TWTK+G PL +++ +S T L I+ + G Y +TV +
Sbjct: 16756 ISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKT 16815
Query: 1056 ATLVLQVVDKPSPPQ-DLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFT 1114
A++ + +DKP PP+ ++ D ++ L W PP G ++ Y VQK D T W
Sbjct: 16816 ASIEIVTLDKPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDV 16875
Query: 1115 VLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKA 1174
V RT V +L G Y FR+F++N G S A +P+ P Y+ P
Sbjct: 16876 VSATVARTTLKVTKLKTGTEYQFRIFAENRYGQS--FALESDPIVAQYP---YKEPGPPG 16930
Query: 1175 LDFSEAPSFTQPLV--NRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSK 1232
F+ A S ++ + V G + ++ + + I W K + D +F+ +
Sbjct: 16931 TPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNL 16990
Query: 1233 QGVLTLEIR 1241
+ + E R
Sbjct: 16991 EEGIEYEFR 16999
Score = 224 bits (571), Expect = 4e-58
Identities = 156/532 (29%), Positives = 231/532 (43%), Gaps = 44/532 (8%)
Query: 622 ACNLSAKLHFME--VKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAP 679
A N+ + E +I+ V R E P + L + T+ + AG LRL V +SG P P
Sbjct: 22922 AVNVKGMSEYSESIAEIEPVERIEIPDLEL--ADDLKKTVTIRAGASLRLMVSVSGRPPP 22979
Query: 680 TVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVE 739
+ W K QG + R ++TT+ S+ V+
Sbjct: 22980 VITWSK---QG----------------------------IDLASRAIIDTTESYSLLIVD 23008
Query: 740 GAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDG 799
+ D G YT+ +N G+ + VKV D P + K+ V DS T+ WE P DG
Sbjct: 23009 KVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDG 23068
Query: 800 GQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSP 859
G P+ YI+E K++ + R + + + ++EG +Y RV N G+ P
Sbjct: 23069 GAPVNNYIVE-KREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCE 23127
Query: 860 ASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEW--- 916
S + P P L V DV+ +TV+L W P G L GY +E C G W
Sbjct: 23128 TSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKV 23187
Query: 917 VAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLP 976
V + EHT V L G + LFR+RA N G P T VTVQ++ P + L
Sbjct: 23188 VTLKPTVLEHT---VTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLS 23244
Query: 977 RHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPL-AGEEVSIRNSPTDTILFIRAA 1035
++TI G PV L+IP G+P P +W G L E V++ L IR
Sbjct: 23245 TMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRET 23304
Query: 1036 RRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQ-DLRVTDAWGLNVALEWKPPQDVGN 1094
+G Y + ++ T+ + ++DKP PP +++ + ++ + W+PP+ G
Sbjct: 23305 TIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEPPELDGG 23364
Query: 1095 TELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVG 1146
L GY V++ D W V E R+ L GN Y FRV + N G
Sbjct: 23365 APLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFG 23416
Score = 220 bits (561), Expect = 6e-57
Identities = 171/617 (27%), Positives = 257/617 (41%), Gaps = 63/617 (10%)
Query: 575 GVWLKNGKELVPDSRIKVSHI--GRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFM 632
G W K E +R V+ + G +K + + A + D +C ++
Sbjct: 21801 GDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGD--------SCEVTGT---- 21848
Query: 633 EVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNK 692
I V R P++ +D T VV AG +RL + G P PT +W K
Sbjct: 21849 ---IKAVDRLTAPELDIDA--NFKQTHVVRAGASIRLFIAYQGRPTPTAVWSK------- 21896
Query: 693 APARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVT 752
PD+ R + TT S TVE + D G YT+T
Sbjct: 21897 ------PDS------------------NLSLRADIHTTDSFSTLTVENCNRNDAGKYTLT 21932
Query: 753 VKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKK 812
V+N G + TVKV+D P P +V S T+ W+ P DGG I Y++E+++
Sbjct: 21933 VENNSGSKSITFTVKVLDTPGPPGPITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKRE 21992
Query: 813 KKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSE 872
W ++ +++ + + EGV Y RV AVN G+ P +P + P+
Sbjct: 21993 ASRRSWQVISEKCTRQI-FKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAP 22051
Query: 873 PTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVK 932
P L V D S ++ L W P+ G + GY +E +G WV A G T+ + V+
Sbjct: 22052 PRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEA--GHTKQLTFTVE 22109
Query: 933 DLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVN 992
L FRV+A N AG P V ++E P L Q I K G P
Sbjct: 22110 RLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFT 22169
Query: 993 LLIPFQGKPRPQVTWTKEGQPL-AGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIEN 1051
+ +P G+P P+VTW E L + VSI + T L ++ + R SG Y +T+
Sbjct: 22170 IDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTA 22229
Query: 1052 MEDKATLVLQVVDKPSP-PQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTM 1110
++ + V+ +P P + V+ + L W P+D G TE+ Y V+K + T
Sbjct: 22230 GVKTFSVTVVVIGRPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTT 22289
Query: 1111 EWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFS---DRAATTKEPVFIP-----R 1162
W V +RT V L Y FRV S+N G S + A E F+P R
Sbjct: 22290 AWQLVNSSVKRTQIKVTHLTKYMEYSFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPTR 22349
Query: 1163 PGITYEPPNYKALDFSE 1179
P + + N ++ + E
Sbjct: 22350 PEVYHVSANAMSIRWEE 22366
Score = 219 bits (559), Expect = 1e-56
Identities = 172/604 (28%), Positives = 278/604 (46%), Gaps = 64/604 (10%)
Query: 577 WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKI 636
W+K +EL +R+++ L++ D D +Y + A S ++ VK+
Sbjct: 16080 WIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVN---VKV 16136
Query: 637 DFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPAR 696
LD PG P+ VV++G ++ + T+ W+ + G
Sbjct: 16137 ------------LDRPGP-PEGPVVISG--------VTAEKC-TLAWKPPLQDGGS---- 16170
Query: 697 PAPDAPEDTGDSDEWVFDKK---LLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTV 753
D ++ +++ L T V+T + +EG +E + +
Sbjct: 16171 ----------DIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEG----NEYTFRIMA 16216
Query: 754 KNPVG-----EDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYIL 808
N G E + + VPDAP AP+++ V +DS V WE PA DGG ILGY+L
Sbjct: 16217 VNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPASDGGSEILGYVL 16276
Query: 809 ERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPAS---QPFM 865
E++ K+ RW R + LI EL +IE YE RV A NA G+S PSP S +
Sbjct: 16277 EKRDKEGIRWTRCHKRLIGELRLRVTGLIENHDYEFRVSAENAAGLSEPSPPSAYQKACD 16336
Query: 866 PIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAAL--QGL 923
PI P P + V D++ ++V L W P G + GY VE C EW G+
Sbjct: 16337 PIYKPGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGI 16396
Query: 924 TEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTI 983
+ T+I V+ L FR+ A N AG G P+ V+E L+ P + L LR+ I
Sbjct: 16397 NK-TNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDLELRKII 16455
Query: 984 QKKVGEPVNLLIPFQGKPRPQVTWTK-EGQPLAGEEVSIRNSPTDTILFIRAARRVHSGT 1042
+ G + L +P +G+P P+V W K +G+ + + +S T +L R SG
Sbjct: 16456 NIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLVL--DNVNRYDSGK 16513
Query: 1043 YQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTV 1102
Y +T+ + A + ++V+D PSPP +L+VT+ +V++ W+PP G +++ Y V
Sbjct: 16514 YTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIV 16573
Query: 1103 QKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPV---F 1159
+K + + V+ + + + +L G YYFRV ++N G A T +P+
Sbjct: 16574 EKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIG-LPAQTADPIKVAE 16632
Query: 1160 IPRP 1163
+P+P
Sbjct: 16633 VPQP 16636
Score = 219 bits (557), Expect = 2e-56
Identities = 152/493 (30%), Positives = 234/493 (47%), Gaps = 38/493 (7%)
Query: 700 DAPEDTGDSD--EWVFDKKLLCETEGRVRVETTKDRSIFT----VEGAEKEDEGVYTVTV 753
D PED G + ++ +K CET+ V +T ++ T V + +E ++ V
Sbjct: 11821 DPPEDDGGCEIQNYILEK---CETKRMVW--STYSATVLTPGTTVTRLIEGNEYIFRVRA 11875
Query: 754 KNPVGEDQVNLTVKVI-----DVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYIL 808
+N +G + VI D P P P+++ V ++ TV W PP YDGG+ I GY L
Sbjct: 11876 ENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFL 11935
Query: 809 ERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM--- 865
E+K+K S RW+ +N I E + + ++ Y+ RV A N IG+ PS S+P +
Sbjct: 11936 EKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKD 11995
Query: 866 PIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCP--------EGCSEWV 917
PI PP PT+ V D + +++L W P G + GY VE P EG
Sbjct: 11996 PIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCN 12055
Query: 918 AALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPR 977
AA Q + + V L FRV A N G G P E + +EIL+ P + L
Sbjct: 12056 AAAQLVRK--EFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEPPEIDLDA 12113
Query: 978 HLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARR 1037
+R+ + + G P+ L +G+P P+VTW K G + + T L I + R
Sbjct: 12114 SMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDTMAFLVIPNSTR 12173
Query: 1038 VHSGTYQVTVRIENMEDKATLV-LQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTE 1096
SG Y +T+ + +KA V ++V+D P P DL+V+D + + W PP++ G ++
Sbjct: 12174 DDSGKYSLTL-VNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQ 12232
Query: 1097 LWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKE 1156
+ Y V+K + W TV ++T V L+ GN YYFRV + N G
Sbjct: 12233 VTHYIVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYG-------PGV 12285
Query: 1157 PVFIPRPGITYEP 1169
P +P+P + +P
Sbjct: 12286 PTDVPKPVLASDP 12298
Score = 218 bits (554), Expect = 4e-56
Identities = 174/627 (27%), Positives = 269/627 (42%), Gaps = 72/627 (11%)
Query: 573 VRGV------WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLS 626
+RGV W +G E+ D V LTI + D +Y A + +
Sbjct: 11037 IRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKT 11096
Query: 627 AKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKA 686
+H LD PG I + LDV T+ WQ
Sbjct: 11097 VAVHLTV---------------LDVPGPPTGPINI-------LDVT---PEHMTISWQP- 11130
Query: 687 ITQGNKAPARPAPDAPEDTGDSD--EWVFDKK-LLCETEGRVRVETTKDRSIFTVEGAEK 743
P+D G S ++ +K+ +T G V ++K + + +K
Sbjct: 11131 ---------------PKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTK--LKIPHLQK 11173
Query: 744 EDEGVYTVTVKNPVG-----EDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYD 798
E V+ V +N +G + + P P P ++++ E++ TV W P D
Sbjct: 11174 GCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWTLPKSD 11233
Query: 799 GGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPS 858
GG PI GY +ER++ +W+R+N I +L + EG YE RV+A N G+S+PS
Sbjct: 11234 GGSPITGYYMERREVTG-KWVRVNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPS 11292
Query: 859 PASQPFM---PIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSE 915
P+S P PI PP P + ++D S T L W P G + GY VE G ++
Sbjct: 11293 PSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQ 11352
Query: 916 WVAALQG-LTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQ 974
W + L + V L G FR++A N+ G G P E V ++IL P ++
Sbjct: 11353 WNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVE 11412
Query: 975 LPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEE-VSIRNSPTDTILFIR 1033
L R I +VG+ + +L +G+P P +TWTKEG+ L E+ V + L I+
Sbjct: 11413 LDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIK 11472
Query: 1034 AARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVG 1093
A R G Y ++ + + + + ++ V+D+P P Q+L+VT+ N + W+ P D G
Sbjct: 11473 EAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKENCTISWENPLDNG 11532
Query: 1094 NTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAAT 1153
+E+ + V+ W V + + L+ N YYFRV ++N VG
Sbjct: 11533 GSEITNFIVEYRKPNQKGWSIVASDVTK-RLIKANLLANNEYYFRVCAENKVGVGP-TIE 11590
Query: 1154 TKEPVF----IPRPGITYEPPNYKALD 1176
TK P+ I RPG EP N D
Sbjct: 11591 TKTPILAINPIDRPG---EPENLHIAD 11614
Score = 218 bits (554), Expect = 4e-56
Identities = 153/548 (27%), Positives = 243/548 (44%), Gaps = 49/548 (8%)
Query: 633 EVKIDFVPRQ--EPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQG 690
E+K P++ EPP+I LD R ++V AG +RL + G PAP V W+K G
Sbjct: 12093 ELKEAIKPKEILEPPEIDLDASMR--KLVIVRAGCPIRLFAIVRGRPAPKVTWRKV---G 12147
Query: 691 NKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYT 750
R +V+ + + + ++D G Y+
Sbjct: 12148 IDNVVRKG---------------------------QVDLVDTMAFLVIPNSTRDDSGKYS 12180
Query: 751 VTVKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILER 810
+T+ NP GE V + V+V+D P + K+S+V + SC V W PP DGG + YI+E+
Sbjct: 12181 LTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEK 12240
Query: 811 KKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PI 867
++ W + + +++ S ++ G Y RV AVN G P+ +P + P+
Sbjct: 12241 READRKTWSTVTPE-VKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPL 12299
Query: 868 GPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEG--CSEWVAALQGLTE 925
P P L V +++ + +L W PP R G +DGY Y E W + +
Sbjct: 12300 SEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTE--YSVVK 12357
Query: 926 HTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQK 985
S++V L G + FRV A N G P +E L P++ +P + I
Sbjct: 12358 DLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMP----EQITI 12413
Query: 986 KVGEPVNLLIPFQGKPRPQVTWTK-EGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQ 1044
K G+ + + GKP P W K E + + +++ + + +IL I+ R SG Y
Sbjct: 12414 KAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYS 12473
Query: 1045 VTVRIENMEDKATLVLQVVDKPSPPQD-LRVTDAWGLNVALEWKPPQDVGNTELWGYTVQ 1103
+T + D + + V+D P PPQ ++D +L W P + G + + Y V+
Sbjct: 12474 LTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSLSWHIPLEDGGSNITNYIVE 12533
Query: 1104 KADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRP 1163
K D +W T L +T C V +LI G Y FRV ++N G S+ + K P
Sbjct: 12534 KCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPF- 12592
Query: 1164 GITYEPPN 1171
G+ EP N
Sbjct: 12593 GVPSEPKN 12600
Score = 217 bits (552), Expect = 7e-56
Identities = 151/520 (29%), Positives = 234/520 (45%), Gaps = 42/520 (8%)
Query: 636 IDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPA 695
I+ R P + LD R D IVV AG +R+ +SG P PTV W
Sbjct: 10016 IEMKDRLVSPDLQLDASVR--DRIVVHAGGVIRIIAYVSGKPPPTVTWNMN--------E 10065
Query: 696 RPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKN 755
R P +ETT S ++ ++ +GVY++ KN
Sbjct: 10066 RTLPQ-----------------------EATIETTAISSSMVIKNCQRSHQGVYSLLAKN 10102
Query: 756 PVGEDQVNLTVKVIDVPDAPAAPKIS-NVGEDSCTVQWEPPAYDGGQPILGYILERKKKK 814
GE + + V V+DVP P ++ N+ +SC + W P DGG PI Y++E+++
Sbjct: 10103 EAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESD 10162
Query: 815 SYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PIGPPS 871
W + + + ++ + + +I+G Y R+ A N+IGM S+ + PI P
Sbjct: 10163 RRAWTPVTYTVTRQ-NATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPE 10221
Query: 872 EPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILV 931
P L V++V+ TV+L W PP+ G + Y +E G ++ V
Sbjct: 10222 RPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTV 10281
Query: 932 KDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPV 991
K L G +RV A N+ G G P T+P+T ++ L P L L + TI +VGE
Sbjct: 10282 KGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHLDFRDKLTI--RVGEAF 10339
Query: 992 NLLIPFQGKPRPQVTWTK-EGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIE 1050
L + GKP+P+V+W K E L + I+ +P L A+R SG Y V V
Sbjct: 10340 ALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENS 10399
Query: 1051 NMEDKATLVLQVVDKPSPPQD-LRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKT 1109
K + VVD+P PP + + + + WKPP D G +++ Y ++K +
Sbjct: 10400 TGSRKGFCQVNVVDRPGPPVGPVSFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGK 10459
Query: 1110 MEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSD 1149
W V +T C V +L+ G Y FR+ ++N+ G SD
Sbjct: 10460 DVWMPVTSASAKTTCKVSKLLEGKDYIFRIHAENLYGISD 10499
Score = 214 bits (546), Expect = 3e-55
Identities = 169/608 (27%), Positives = 283/608 (46%), Gaps = 58/608 (9%)
Query: 643 EPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAP 702
E P+I LD R +++ AG +++ +P G P PTV W+K
Sbjct: 20770 EAPEIDLDVALRT--SVIAKAGEDVQVLIPFKGRPPPTVTWRK----------------- 20810
Query: 703 EDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQV 762
D+K L ++ R +E T S+ T+ + D G Y +T++N VGE +
Sbjct: 20811 -----------DEKNL-GSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKS 20858
Query: 763 N-LTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRL 821
+ ++VKV+D P A ++ +V + T+ W+PP DGG PI+ Y++E++ W +
Sbjct: 20859 STVSVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVV 20918
Query: 822 NFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDV 881
+ S + + E + RV A N IG+ P ++P P+ L+++D
Sbjct: 20919 SHKC-SSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDS 20977
Query: 882 SDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLL 941
+ T+V L W P+ G + Y VE +G W A G+++ I V L + L
Sbjct: 20978 TKTSVILSWTKPDFDGGSVITEYVVERKGKGEQTWSHA--GISKTCEIEVSQLKEQSVLE 21035
Query: 942 FRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKP 1001
FRV A N G PVT P+TV+E++ P + L + ++G V+L +P++GKP
Sbjct: 21036 FRVFAKNEKGLSDPVTIG-PITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKP 21094
Query: 1002 RPQVTWTKEGQPLAGEEVSIRNSPTDT--ILFIRAARRVHSGTYQVTVRIENMEDKATLV 1059
+P ++W K+G PL E +R S T+ L I+ A++ H G Y TV ++N + +
Sbjct: 21095 KPSISWLKDGLPLKESEF-VRFSKTENKITLSIKNAKKEHGGKY--TVILDNAVCRIAVP 21151
Query: 1060 LQVV--DKPSPPQ-DLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVL 1116
+ V+ PS P+ +R + +V L W P+D G E+ Y+++K + W V
Sbjct: 21152 ITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTNWKMVC 21211
Query: 1117 EHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATT----KEPVFIPRPGITYEPPNY 1172
RT VP L+ Y FRV ++N G S ++ K IP P +P Y
Sbjct: 21212 SSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGP--PGKPVIY 21269
Query: 1173 KALDFSEAPSFTQPLVN-RSVIAGY-------TAMLCCAVRGSPKPKISWFKNGLDLGED 1224
+ ++ P+ + S + G+ ++L V SP + GL G D
Sbjct: 21270 NVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLD 21329
Query: 1225 ARFRMFSK 1232
+FR++++
Sbjct: 21330 YQFRVYAE 21337
Score = 213 bits (543), Expect = 7e-55
Identities = 137/438 (31%), Positives = 210/438 (47%), Gaps = 12/438 (2%)
Query: 732 DRSIFTVEGAEKEDEGVYTVTVKNPVG-----EDQVNLTVKVIDVPDAPAAPKISNVGED 786
+ I T K +E ++ V N G E + P P P+++ + ++
Sbjct: 20524 EECIITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKN 20583
Query: 787 SCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRV 846
S TV W P DGG I GY LE++ KKS W ++ + I++ + + E Y+ RV
Sbjct: 20584 SMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRV 20643
Query: 847 YAVNAIGM---SRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDG 903
AVNA G S PS + PI PP P + + D + ++++L W P G + G
Sbjct: 20644 CAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTG 20703
Query: 904 YSVEYCPEGCSEWVA-ALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPV 962
Y VE EW + +G T +V +L G FRV A N AG G P+ EPV
Sbjct: 20704 YVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPV 20763
Query: 963 TVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGE-EVSI 1021
++IL+ P + L LR ++ K GE V +LIPF+G+P P VTW K+ + L + SI
Sbjct: 20764 QAKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSI 20823
Query: 1022 RNSPTDTILFIRAARRVHSGTYQVTVRIENMEDK-ATLVLQVVDKPSPPQDLRVTDAWGL 1080
N+ + ++L I R +G Y +T+ E K +T+ ++V+D P+ Q L+V
Sbjct: 20824 ENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRG 20883
Query: 1081 NVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVF 1140
V L W PP G + + Y ++K D W V T + +L ++FRV
Sbjct: 20884 TVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVL 20943
Query: 1141 SQNMVGFSDRAATTKEPV 1158
++N +G + TT EPV
Sbjct: 20944 AENEIGIGEPCETT-EPV 20960
Score = 212 bits (540), Expect = 2e-54
Identities = 170/605 (28%), Positives = 264/605 (43%), Gaps = 59/605 (9%)
Query: 641 RQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPD 700
R PP+I LD R + + A LRL VPI G PAP V W +
Sbjct: 15357 RMLPPEIELDADLR--KVVTIRACCTLRLFVPIKGRPAPEVKWAR--------------- 15399
Query: 701 APEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGED 760
D G+S + + +E+T ++ V + D G Y +TV+N G
Sbjct: 15400 ---DHGESLD-------------KASIESTSSYTLLIVGNVNRFDSGKYILTVENSSGSK 15443
Query: 761 QVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKK--KKSYRW 818
+ V+V+D P P K+ V + S T+ W+PP DGG I YI+E+++ +K+Y
Sbjct: 15444 SAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVEKRESTRKAYST 15503
Query: 819 MRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAV 878
+ N + S + ++ EG Y RV A N G+ P+ ++ P P + +
Sbjct: 15504 VATN---CHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKASERPLPPGKITL 15560
Query: 879 EDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGA 938
DV+ +VSL W PE G + GY VE +G +W A + T + L G
Sbjct: 15561 MDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKW--ATCATVKVTEATITGLIQGE 15618
Query: 939 RLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQ 998
FRV A N G P + PV ++++ P +L L T GE + + +PF
Sbjct: 15619 EYSFRVSAQNEKGISDPRQLSVPVIAKDLVIPPAFKL---LFNTFTVLAGEDLKVDVPFI 15675
Query: 999 GKPRPQVTWTKEGQPL-AGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKAT 1057
G+P P VTW K+ PL V+ ++ +++L I+ A R G Y V + E T
Sbjct: 15676 GRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIET 15735
Query: 1058 LVLQVVDKPSPPQ-DLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVL 1116
L + V+DKP PP +++ + ++ L W PP+ G + + Y V+K D T W V
Sbjct: 15736 LNVIVLDKPGPPTGPVKMDEVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTWQIVS 15795
Query: 1117 EHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALD 1176
RT L G Y FR+ ++N G S EP P PP +
Sbjct: 15796 ATVARTTIKACRLKTGCEYQFRIAAENRYGKS--TYLNSEPTVAQYPFKVPGPPGTPVVT 15853
Query: 1177 FSEAPS----FTQPLVN-RSVIAGY-------TAMLCCAVRGSPKPKISWFKNGLDLGED 1224
S S + +P+ + S + GY ++L + +P P+ + GL+ G +
Sbjct: 15854 LSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGVE 15913
Query: 1225 ARFRM 1229
FR+
Sbjct: 15914 YEFRV 15918
Score = 211 bits (537), Expect = 4e-54
Identities = 158/561 (28%), Positives = 244/561 (43%), Gaps = 48/561 (8%)
Query: 644 PPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPE 703
PP+ LD R T+++ AG +RL VP+ G P P + W K P + +
Sbjct: 13193 PPEGELDADLR--KTLILRAGVTMRLYVPVKGRPPPKITWSK-----------PNVNLRD 13239
Query: 704 DTG-DSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQV 762
G D FD L C E K D G Y +T++N G+ +
Sbjct: 13240 RIGLDIKSTDFDTFLRC-------------------ENVNKYDAGKYILTLENSCGKKEY 13280
Query: 763 NLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLN 822
+ VKV+D P P + + +DS V WEPP DGG PI+ Y+++++ + W +
Sbjct: 13281 TIVVKVLDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVT 13340
Query: 823 FDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVS 882
+ + S + EG Y RV+A N G+ P P L V VS
Sbjct: 13341 TE-CSKTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVVDLKVRSVS 13399
Query: 883 DTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLF 942
++ S+ W+ P G + GY V++ E ++W ++ L+ S KDL G F
Sbjct: 13400 KSSCSIGWKKPHSDGGSRIIGYVVDFLTEE-NKWQRVMKSLSLQYS--AKDLTEGKEYTF 13456
Query: 943 RVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPR 1002
RV A N G G P T V ++ + P L L K L IP +GKP
Sbjct: 13457 RVSAENENGEGTPSEIT--VVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPA 13514
Query: 1003 PQVTWTKEGQPLAGE-EVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQ 1061
P V+W K PLA + VS+ +S +T L + ++ +G Y +T++ + T+ ++
Sbjct: 13515 PSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIK 13574
Query: 1062 VVDKPS-PPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYR 1120
VV KP P ++ + + L+W PP+D G +E+ Y ++K D +W T +
Sbjct: 13575 VVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCASAVQ 13634
Query: 1121 RTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRP-GITYEPPNYKALDF-- 1177
+T V L G Y FRV ++N G + EP+ P + PP +D
Sbjct: 13635 KTTFRVTRLHEGMEYTFRVSAENKYGVGE--GLKSEPIVARHPFDVPDAPPPPNIVDVRH 13692
Query: 1178 -SEAPSFTQP-LVNRSVIAGY 1196
S + ++T P S I GY
Sbjct: 13693 DSVSLTWTDPKKTGGSPITGY 13713
Score = 211 bits (537), Expect = 4e-54
Identities = 149/517 (28%), Positives = 234/517 (45%), Gaps = 47/517 (9%)
Query: 636 IDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPA 695
++ V R+ P LD R T+VV AG +R+ VPI G PAP V W K
Sbjct: 14268 VEIVEREMAPDFELDAELR--RTLVVRAGLSIRIFVPIKGRPAPEVTWTK---------- 14315
Query: 696 RPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKN 755
D+ + R +E T+ ++ + + D G + +T++N
Sbjct: 14316 -----------DN----------INLKNRANIENTESFTLLIIPECNRYDTGKFVMTIEN 14354
Query: 756 PVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKK--K 813
P G+ + V+V+D P + +++ +DS T+ W+ P DGG I YI+E+++ +
Sbjct: 14355 PAGKKSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATR 14414
Query: 814 KSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEP 873
KSY + +++ + EG Y RV A N G+ P+ ++P PS P
Sbjct: 14415 KSYSTATTK---CHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPP 14471
Query: 874 THLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEW--VAALQGLTEHTSILV 931
L + D++ +TVSL W P+ G + GY +E +G +W + ++GL +V
Sbjct: 14472 DSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQWTHITTVKGL----ECVV 14527
Query: 932 KDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPV 991
++L G F+V A N AG AP + PV V+E P L L ++ + K G+ +
Sbjct: 14528 RNLTEGEEYTFQVMAVNSAGRSAP-RESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNI 14586
Query: 992 NLLIPFQGKPRPQVTWTKEGQPL-AGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIE 1050
+ IP G+P+P VTW K Q L + V+ + T TIL I R SG Y +T R
Sbjct: 14587 KVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNI 14646
Query: 1051 NMEDKATLVLQVVDKPSPPQ-DLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKT 1109
E + +QV D P PP ++ + V W PP++ G + Y V+ +
Sbjct: 14647 VGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDS 14706
Query: 1110 MEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVG 1146
W + RT L G Y FRV +QN G
Sbjct: 14707 TTWVELATTVIRTTYKATRLTTGLEYQFRVKAQNRYG 14743
Score = 209 bits (531), Expect = 2e-53
Identities = 164/608 (26%), Positives = 257/608 (42%), Gaps = 65/608 (10%)
Query: 577 WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKI 636
W K E+V S + V L I DVT D YS E S+ ++K+
Sbjct: 12435 WKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAEN-----SSGTDTQKIKV 12489
Query: 637 DFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKA-ITQGNKAPA 695
+ PP+ D I D + + G I +K +++G
Sbjct: 12490 VVMDAPGPPQPPFD----ISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRG----- 12540
Query: 696 RPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKN 755
+WV + +T RV + G E ++ V +N
Sbjct: 12541 --------------DWVTALASVTKTSCRVGK---------LIPGQEY----IFRVRAEN 12573
Query: 756 PVGEDQVNLTVKVI-----DVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILER 810
G + + K++ VP P +++ V +D V W+ P DGG PI+GY++ER
Sbjct: 12574 RFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIER 12633
Query: 811 KKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQ---PFMPI 867
K++ S W++ N L++ + ++EG+ Y R+YA+N G S PS ++ MP+
Sbjct: 12634 KERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPV 12693
Query: 868 GPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTE-- 925
PP +P V DV+ +TVSL W P+ G + GY VE C +WV +
Sbjct: 12694 DPPGKP---EVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIP 12750
Query: 926 HTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQK 985
L A+ FR A P ++PVT+ PR+ L ++ +
Sbjct: 12751 QEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVAMKSLLTV 12810
Query: 986 KVGEPVNLLIPFQGKPRPQVTWTKEG---QPLAGEEVSIRNSPTDTILFIRAARRVHSGT 1042
K G V L GKP P V+W K+G +P G +++++ + LF + R SG
Sbjct: 12811 KAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELF--SVNRKDSGD 12868
Query: 1043 YQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTV 1102
Y +T + AT+ L+V+DKP PP +++ + L W+PP + G +E+ Y V
Sbjct: 12869 YTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIV 12928
Query: 1103 QKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPR 1162
K + W V T C V +LI G+ Y FR+ ++N G D T EP
Sbjct: 12929 DKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFT--EPAIAKN 12986
Query: 1163 PGITYEPP 1170
P Y+PP
Sbjct: 12987 P---YDPP 12991
Score = 207 bits (526), Expect = 7e-53
Identities = 139/404 (34%), Positives = 194/404 (48%), Gaps = 13/404 (3%)
Query: 771 VPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELS 830
VPDAP P ++ V +DS V W P +DGG+PI YILE+++ S RW R+ D I +
Sbjct: 10514 VPDAPDQPIVTEVTKDSALVTWNKP-HDGGKPITNYILEKRETMSKRWARVTKDPIHPYT 10572
Query: 831 H-EARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PIGPPSEPTHLAVEDVSDTTV 886
++EG YE RV A N IG+ PSP S+P PI PS P + D + +V
Sbjct: 10573 KFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSV 10632
Query: 887 SLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAA--LQGLTEHTSILVKDLPTGARLLFRV 944
L W+PP G + GY VEY G EW A T V L G FRV
Sbjct: 10633 DLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRV 10692
Query: 945 RAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQ 1004
A N AG P EPV V++ L+ P L L ++ + KVG+ + L +G P P+
Sbjct: 10693 LAVNAAGESDPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPK 10752
Query: 1005 VTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVD 1064
VTW KE + A + I +P + L IR A G Y +TV ++ + V+D
Sbjct: 10753 VTWKKEDRD-APTKARIDVTPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLD 10811
Query: 1065 KPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHC 1124
KP PP+DL V++ + L WK P D G + + Y V++ D + +W + ++
Sbjct: 10812 KPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSH 10871
Query: 1125 VVPELIIGNGYYFRVFSQNMVGFSDRAATTK-----EPVFIPRP 1163
L GN Y FRV ++N G T K +P+ P P
Sbjct: 10872 FAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGP 10915
Score = 206 bits (524), Expect = 1e-52
Identities = 169/608 (27%), Positives = 260/608 (42%), Gaps = 74/608 (12%)
Query: 577 WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFV---PEGFACNLSAKLHFME 633
W K+GKEL +++++ L D T D Y+ P GFA H
Sbjct: 14998 WSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGGFA------KHIFN 15051
Query: 634 VKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKA 693
VK+ LD PG P G A T + + K
Sbjct: 15052 VKV------------LDRPG------------------PPEGPLAVTEVTSE------KC 15075
Query: 694 PARPAPDAPEDTGDSDEWVFDKK---LLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYT 750
P + D ++ K+ L T V+ TK + ++G +E ++
Sbjct: 15076 VLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKG----NEYIFR 15131
Query: 751 VTVKNPVG-----EDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILG 805
V N G E + L V PD P P+++ + +DS V W P DGG I+
Sbjct: 15132 VMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIIN 15191
Query: 806 YILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM 865
YI+ER+ K RW++ N + +L ++ + EG YE R+ A NA G+S PSP S PF
Sbjct: 15192 YIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTS-PFY 15250
Query: 866 PI-------GPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEW-- 916
GPP P V D S +++S+ W P G + GY VE EW
Sbjct: 15251 KACDTVFKPGPPGNP---RVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQI 15307
Query: 917 VAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLP 976
V GL + TS + L R+ A N G G P ++ + P ++L
Sbjct: 15308 VTPPAGL-KATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEIELD 15366
Query: 977 RHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKE-GQPLAGEEVSIRNSPTDTILFIRAA 1035
LR+ + + + L +P +G+P P+V W ++ G+ L ++ SI ++ + T+L +
Sbjct: 15367 ADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDHGESL--DKASIESTSSYTLLIVGNV 15424
Query: 1036 RRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNT 1095
R SG Y +TV + A + ++V+D P PPQDL+V + +V L W PP G +
Sbjct: 15425 NRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGS 15484
Query: 1096 ELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTK 1155
++ Y V+K + + TV + +T V +L G YYFRV ++N G A T +
Sbjct: 15485 KIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAE 15544
Query: 1156 EPVFIPRP 1163
RP
Sbjct: 15545 SVKASERP 15552
Score = 205 bits (522), Expect = 2e-52
Identities = 166/590 (28%), Positives = 260/590 (44%), Gaps = 57/590 (9%)
Query: 577 WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKI 636
W K+G L P IK++ + L + V D DY+ E + + SA + ++K+
Sbjct: 12832 WKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATI---KLKV 12888
Query: 637 DFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPAR 696
LD PG P V + NK+ D + + W+ + G
Sbjct: 12889 ------------LDKPG--PPASVKI--NKMYSDRAM-------LSWEPPLEDGGS---- 12921
Query: 697 PAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNP 756
+ ++ DK+ +V T + +VE + E + + +N
Sbjct: 12922 ----------EITNYIVDKRETSRPNW-AQVSATVPITSCSVEKLIEGHEYQFRICAENK 12970
Query: 757 VGEDQVNLTVKVI-----DVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERK 811
G T I D P P ISN+ +D TV W+PPA DGG PI GY+LE++
Sbjct: 12971 YGVGDPVFTEPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKR 13030
Query: 812 KKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQ------PFM 865
+ ++ W ++N I E + +A + EG YE RV A+N G +PS AS+ P
Sbjct: 13031 ETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQY 13090
Query: 866 PIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAA-LQGLT 924
P GPP+ P V D + ++VSL W P G + GY VE WV L
Sbjct: 13091 PPGPPAFP---KVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNL 13147
Query: 925 EHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQ 984
+ T V L + FRV A N G P + ++IL P +L LR+T+
Sbjct: 13148 QKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLI 13207
Query: 985 KKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGE-EVSIRNSPTDTILFIRAARRVHSGTY 1043
+ G + L +P +G+P P++TW+K L + I+++ DT L + +G Y
Sbjct: 13208 LRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKY 13267
Query: 1044 QVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQ 1103
+T+ + + T+V++V+D P PP ++ V + + + W+PP G + + Y VQ
Sbjct: 13268 ILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQ 13327
Query: 1104 KADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAAT 1153
K D + W TV +T V L G Y+FRVF++N G D T
Sbjct: 13328 KRDAERKSWSTVTTECSKTSFRVANLEEGKSYFFRVFAENEYGIGDPGET 13377
Score = 204 bits (519), Expect = 4e-52
Identities = 155/574 (27%), Positives = 256/574 (44%), Gaps = 43/574 (7%)
Query: 632 MEVKIDFVPRQEPPKIHLDCPGRIPD---TIVVVAGNKL-----RLDVPISGDPAPTVIW 683
+++ + V R E K L P + + T V A N+L + V + P+P
Sbjct: 8949 LQITKEEVSRSEA-KTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPR-- 9005
Query: 684 QKAITQGNKAPARPAPDAPEDTGDSD--EWVFDKKLLCETEGR-VRVETTKDRSIFTVEG 740
A+T DAP D G S+ +V DK+ + V T + +
Sbjct: 9006 NLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWK 9065
Query: 741 AEKEDEGVYTVTVKNPVGEDQVNLTVKVI-----DVPDAPAAPKISNVGEDSCTVQWEPP 795
+ + V N G + KV+ +P P PK+ + S V W PP
Sbjct: 9066 LIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPP 9125
Query: 796 AYDGGQPILGYILERKKKKSYRWMRLNFDLIQELS-----HEARRMIEGVVYEMRVYAVN 850
+GG PI GY LE++++ S W R++ I ++ R++EGV Y+ R A+N
Sbjct: 9126 LDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAIN 9185
Query: 851 AIGMSRPSPASQPFM---PIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVE 907
A G+ PS S P + PI PP P+ V+D + +++SL W+PP + G + GY VE
Sbjct: 9186 AAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVE 9245
Query: 908 YCPEGCSEW--VAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQ 965
EG ++W V L +V +L + FRV+A N AG P TT +
Sbjct: 9246 MQEEGTTDWKRVNEPDKLITTCECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPAT 9305
Query: 966 EILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSP 1025
+I + P + + + + K G + + +G+P P+ +W +G+ + + + P
Sbjct: 9306 DIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIP 9365
Query: 1026 TD---------TILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTD 1076
D +++ I +R H+G Y +T + + + A ++V+D P PP+DL+V+D
Sbjct: 9366 EDAQLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDLKVSD 9425
Query: 1077 AWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYY 1136
+ L WK P D G + GY ++K W V T VVP+L+ Y+
Sbjct: 9426 ITRGSCRLSWKMPDDDGGDRIKGYVIEKRTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYF 9485
Query: 1137 FRVFSQNMVGFSD-----RAATTKEPVFIPRPGI 1165
FRV ++N G + T ++P++ P P I
Sbjct: 9486 FRVRAENRFGIGPPVETIQRTTARDPIYPPDPPI 9519
Score = 203 bits (516), Expect = 1e-51
Identities = 156/577 (27%), Positives = 241/577 (41%), Gaps = 75/577 (12%)
Query: 659 IVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLL 718
I+V+ G KL + VP P PTV W K D E
Sbjct: 7899 IIVIEGEKLSIPVPFRAVPVPTVSWHK---------------------DGKE-------- 7929
Query: 719 CETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAP 778
+ R+ ++ + V + + D G+YT+T++N +G ++ VKVI +P
Sbjct: 7930 VKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKDI 7989
Query: 779 KISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIE 838
K S++ + SC + WEPP +DGG PIL Y+LER++ ++ + +LS + +I
Sbjct: 7990 KASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPV-MSGENKLSWTVKDLIP 8048
Query: 839 GVVYEMRVYAVNAIGMSRPSPASQPFM---PIGPPSEPTHLAVEDVSDTTVSLKWRPPER 895
Y RV AVN +G P + P PP P + V + + +++ W+PP
Sbjct: 8049 NGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITWKPPLY 8108
Query: 896 VGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAP 955
G + GY +E +G W + L + K L G FRVRA N AG P
Sbjct: 8109 DGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTYTAKGLEEGKEYQFRVRAENAAGISEP 8168
Query: 956 VTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLA 1015
T P + + P++ L R +++ K G+ + L G P P +TW K+ +
Sbjct: 8169 SRATPPTKAVDPIDAPKVIL----RTSLEVKRGDEIALDASISGSPYPTITWIKDENVIV 8224
Query: 1016 GEEVSIRNSPT------------------------------DTILFIRAARRVHSGTYQV 1045
EE+ R +P ++ L +R + R G Y +
Sbjct: 8225 PEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMI 8284
Query: 1046 TVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKA 1105
V ++ KA + V+D P PP + D +V +W+PP D G +E+ YT++K
Sbjct: 8285 KVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCKWEPPLDDGGSEIINYTLEKK 8344
Query: 1106 D--KKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVG----FSDRAATTKEPVF 1159
D K EW V R V +LI G Y FRV ++N G + K+P F
Sbjct: 8345 DKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKPLVAKDP-F 8403
Query: 1160 IPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGY 1196
P P +P S + +P N S I GY
Sbjct: 8404 GP-PDAPDKPIVEDVTSNSMLVKWNEPKDNGSPILGY 8439
Score = 202 bits (514), Expect = 2e-51
Identities = 143/504 (28%), Positives = 223/504 (44%), Gaps = 23/504 (4%)
Query: 727 VETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGE----DQVNLTVKV-IDVPDAPAAPKIS 781
V T R++ V +E + + +N G D +TVK+ P P+ P ++
Sbjct: 20123 VSATVARTMMKVMKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVT 20182
Query: 782 NVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVV 841
NV +S TV W P +GG ++GY LE K + S W + N +I+ + + G++
Sbjct: 20183 NVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLI 20242
Query: 842 YEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGL 901
YE RVYA NA G+ +PS S+P + I P ++ + D+S +VSL W+ P G +
Sbjct: 20243 YEFRVYAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKI 20302
Query: 902 DGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGP-GAPVTTTE 960
GY VE W A T ++ L ++ FRV A N G P
Sbjct: 20303 TGYIVERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVG 20362
Query: 961 PVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPL-AGEEV 1019
P+T + P + LP + ++ + G V L GKP P + W K+ + L V
Sbjct: 20363 PITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALV 20422
Query: 1020 SIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPP-QDLRVTDAW 1078
+ N+ + I+ A R++SG Y++ +R AT+ +Q++DKP PP +
Sbjct: 20423 CVENTTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVT 20482
Query: 1079 GLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFR 1138
+ L W+PP D G ++ Y V+K + + W V EH ++I GN Y FR
Sbjct: 20483 AEKITLLWRPPADDGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFR 20542
Query: 1139 VFSQNMVGF-----SDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVN-RSV 1192
V + N G SD V PGI P K S +++P+ + S
Sbjct: 20543 VRAVNKYGIGEPLESDSVVAKNAFVTPGPPGI---PEVTKITKNSMTVVWSRPIADGGSD 20599
Query: 1193 IAGYTAMLCCAVRGSPKPKISWFK 1216
I+GY + K + WFK
Sbjct: 20600 ISGY------FLEKRDKKSLGWFK 20617
Score = 202 bits (513), Expect = 2e-51
Identities = 144/471 (30%), Positives = 207/471 (43%), Gaps = 23/471 (4%)
Query: 683 WQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAE 742
W+ + G + + T EW+ L + V +F V
Sbjct: 8325 WEPPLDDGGSEIINYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAEN 8384
Query: 743 KEDEGVYTVT----VKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYD 798
+ G V+ K+P G PDAP P + +V +S V+W P D
Sbjct: 8385 RFGPGPPCVSKPLVAKDPFGP------------PDAPDKPIVEDVTSNSMLVKWNEPK-D 8431
Query: 799 GGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPS 858
G PILGY LE+++ S W R+N L+ L ++EG+ Y RV A NA G + S
Sbjct: 8432 NGSPILGYWLEKREVNSTHWSRVNKSLLNALKANVDGLLEGLTYVFRVCAENAAGPGKFS 8491
Query: 859 PASQP---FMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSE 915
P S P PI PP P V D S TT+ L+W PP G G + GY V+ G +E
Sbjct: 8492 PPSDPKTAHDPISPPGPPIP-RVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNE 8550
Query: 916 WVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQL 975
W + + + VK++ GA RV A N AG G P T+PVTV E + P ++L
Sbjct: 8551 WSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGEGPP-GETQPVTVAEPQEPPAVEL 8609
Query: 976 PRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAA 1035
++ IQ G+ + + G+P P WTKE L + V I N T + L I+ A
Sbjct: 8610 DVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGTKSELIIKDA 8669
Query: 1036 RRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNT 1095
R G Y +T A ++V D P P DL+ L W P+D G +
Sbjct: 8670 LRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGS 8729
Query: 1096 ELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVG 1146
E+ G+ +++ D K W +E R+ C + L+ G Y FRV ++N G
Sbjct: 8730 EITGFIIERKDAKMHTWRQPIE-TERSKCDITGLLEGQEYKFRVIAKNKFG 8779
Score = 201 bits (512), Expect = 3e-51
Identities = 169/574 (29%), Positives = 245/574 (42%), Gaps = 58/574 (10%)
Query: 642 QEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDA 701
QEPP + LD + I ++AG LR+ ++G P PT +W K
Sbjct: 8602 QEPPAVELDVS--VKGGIQIMAGKTLRIPAVVTGRPVPTKVWTK---------------- 8643
Query: 702 PEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQ 761
+E DK RV ++ +S ++ A ++D G Y +T N G
Sbjct: 8644 -------EEGELDKD-------RVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKF 8689
Query: 762 VNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRL 821
V+V DVP K C + W P DGG I G+I+ERK K + W +
Sbjct: 8690 AAARVEVFDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFIIERKDAKMHTWRQ- 8748
Query: 822 NFDLIQELSH-EARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PIGPPSEPTHLA 877
+ E S + ++EG Y+ RV A N G P P + P+GPP+ P L
Sbjct: 8749 --PIETERSKCDITGLLEGQEYKFRVIAKNKFGCGPPVEIG-PILAVDPLGPPTSPERLT 8805
Query: 878 VEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTG 937
+ + +T++L W+ P G + GY +E ++ + L TS LV++L
Sbjct: 8806 YTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEH 8865
Query: 938 ARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLR-QTIQKKVGEPVNLLIP 996
FRV+A N G P V +Q+ P ++L +R TI+ K GEPV++
Sbjct: 8866 QMYEFRVKAVNEIGESEPSLPLN-VVIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPAD 8924
Query: 997 FQGKPRPQVTWTK---------EGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTV 1047
G P P++ W+K + + EEVS S T L I A R GTY VT
Sbjct: 8925 VTGLPMPKIEWSKNETVIEKPTDALQITKEEVS--RSEAKTELSIPKAVREDKGTYTVTA 8982
Query: 1048 RIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKAD- 1106
+ ++V D+PSPP++L VTD + L W P D G +E+ Y + K D
Sbjct: 8983 SNRLGSVFRNVHVEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDA 9042
Query: 1107 -KKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIP--RP 1163
+K EW V + +LI Y FRV + N G SD + K + P P
Sbjct: 9043 SRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLP 9102
Query: 1164 GITYEPPNYKALDFSEAPSFTQPLVN-RSVIAGY 1196
G +P S S+T PL N S I GY
Sbjct: 9103 GPPGKPKVLARTKGSMLVSWTPPLDNGGSPITGY 9136
Score = 201 bits (511), Expect = 4e-51
Identities = 166/600 (27%), Positives = 260/600 (43%), Gaps = 71/600 (11%)
Query: 577 WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKI 636
W K GK++ P +++ LTI T D +Y+ K+ ++V +
Sbjct: 13916 WSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATN---PFGTKVEHVKVTV 13972
Query: 637 DFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPAR 696
LDVP G P P I + KA
Sbjct: 13973 --------------------------------LDVP--GPPGPVEI---SNVSAEKATLT 13995
Query: 697 PAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKD----RSIFT--VEGAEKEDEGVYT 750
P + ++ +K+ ET + ++D R + T ++G +E ++
Sbjct: 13996 WTPPLEDGGSPIKSYILEKR---ETSRLLWTVVSEDIQSCRHVATKLIQG----NEYIFR 14048
Query: 751 VTVKNPVGEDQV--NLTVKVID---VPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILG 805
V+ N G+ + + VK++D P P P++SNV +++ TV W+ P DGG I G
Sbjct: 14049 VSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITG 14108
Query: 806 YILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM 865
Y +ER++KKS RW+R + +L + + EG YE RV A N G+ PS AS +
Sbjct: 14109 YHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVL 14168
Query: 866 ------PIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAA 919
P GPPS P V D + + SL W P G + GY VE+ G W+
Sbjct: 14169 MKDAAYPPGPPSNP---HVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKD 14225
Query: 920 LQGLT-EHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRH 978
G T +V DL T + FR+ A N AG G P + V + E P +L
Sbjct: 14226 TTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVIPD-VEIVEREMAPDFELDAE 14284
Query: 979 LRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRV 1038
LR+T+ + G + + +P +G+P P+VTWTK+ L +I N+ + T+L I R
Sbjct: 14285 LRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLK-NRANIENTESFTLLIIPECNRY 14343
Query: 1039 HSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELW 1098
+G + +T+ + + ++V+D P P +LR TD +V L W P G + +
Sbjct: 14344 DTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRIT 14403
Query: 1099 GYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPV 1158
Y V+K + + T + V L G Y+FRV ++N G + TT EPV
Sbjct: 14404 NYIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETT-EPV 14462
Score = 200 bits (508), Expect = 8e-51
Identities = 169/607 (27%), Positives = 252/607 (41%), Gaps = 59/607 (9%)
Query: 574 RGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFME 633
R W K+G E+ ++++ + L + D T Y+ + + + A++ +
Sbjct: 21492 RVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEI---K 21548
Query: 634 VKIDFVPRQEPPKIHLDCPGRI--PDTIVVVAGNKLRL--DVPISGDPAPTV--IWQKAI 687
VK+ D PG++ P + G K+ L D P++ AP I +K
Sbjct: 21549 VKVQ------------DTPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRE 21596
Query: 688 TQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEG 747
T +R A ED ++ + K L+ E + RV
Sbjct: 21597 T------SRLAWALIEDKCEAQSYTAIK-LINGNEYQFRVSA------------------ 21631
Query: 748 VYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYI 807
V V P+ D V ++ VPDAP P+ SN+ +S T+ W P DGG I YI
Sbjct: 21632 VNKFGVGRPLDSDPVVAQIQYT-VPDAPGIPEPSNITGNSITLTWARPESDGGSEIQQYI 21690
Query: 808 LERKKKKSYRWMR-LNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM- 865
LER++KKS RW++ ++ I E + + EG YE V A NA G+ S S+
Sbjct: 21691 LERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKC 21750
Query: 866 --PIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGL 923
P+ PP PT + V D S TTVSL+W P G + GY +E C +W
Sbjct: 21751 REPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEA 21810
Query: 924 TEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTI 983
T V DL G FRV A N AG G T + + L P L + + +QT
Sbjct: 21811 CVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTH 21870
Query: 984 QKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTY 1043
+ G + L I +QG+P P W+K L+ I + + + L + R +G Y
Sbjct: 21871 VVRAGASIRLFIAYQGRPTPTAVWSKPDSNLS-LRADIHTTDSFSTLTVENCNRNDAGKY 21929
Query: 1044 QVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQ 1103
+TV + T ++V+D P PP + D + L W P G + Y V+
Sbjct: 21930 TLTVENNSGSKSITFTVKVLDTPGPPGPITFKDVTRGSATLMWDAPLLDGGARIHHYVVE 21989
Query: 1104 KADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRP 1163
K + W + E R V +L G YYFRV + N G EP +P P
Sbjct: 21990 KREASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVG-------EPYEMPEP 22042
Query: 1164 GITYEPP 1170
+ E P
Sbjct: 22043 IVATEQP 22049
Score = 199 bits (507), Expect = 1e-50
Identities = 128/407 (31%), Positives = 195/407 (47%), Gaps = 14/407 (3%)
Query: 771 VPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELS 830
VP P P+++ V +DS T+ W P DGG PILGY +ERK++ W ++ L+
Sbjct: 14761 VPGPPGTPQVTAVTKDSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNI 14820
Query: 831 HEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PIGPPSEPTHLAVEDVSDTTVS 887
++ + +G+ YE RV A N G S+PS S+P + PI PP +P L +++ TV+
Sbjct: 14821 FKSSGLTDGIAYEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPL---NITRHTVT 14877
Query: 888 LKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAH 947
LKW PE G + Y VE W+ A V L A FRV A
Sbjct: 14878 LKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAK 14937
Query: 948 NMAGP-GAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVT 1006
N AG P ++ +T ++ ++ P++++ + T+ K GE L G+P P +
Sbjct: 14938 NAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTME 14997
Query: 1007 WTKEGQPLAG-EEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDK 1065
W+K+G+ L G ++ I+ + T L + + R SG Y +T K ++V+D+
Sbjct: 14998 WSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDR 15057
Query: 1066 PSPPQ-DLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHC 1124
P PP+ L VT+ L W PP D G ++ Y VQK + + W V + T
Sbjct: 15058 PGPPEGPLAVTEVTSEKCVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKL 15117
Query: 1125 VVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPN 1171
V +L+ GN Y FRV + N G + EPV P Y PP+
Sbjct: 15118 KVTKLLKGNEYIFRVMAVNKYGVGE--PLESEPVLAVNP---YGPPD 15159
Score = 199 bits (506), Expect = 1e-50
Identities = 156/565 (27%), Positives = 253/565 (44%), Gaps = 26/565 (4%)
Query: 702 PEDTGDSD--EWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGE 759
P+D G S+ ++ +K+ + V + ++ F V + E + V+ +N G
Sbjct: 13603 PKDDGGSEITNYILEKRDSVNNKW-VTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGV 13661
Query: 760 DQVNLTVKVI-----DVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKK 814
+ + ++ DVPDAP P I +V DS ++ W P GG PI GY LE K++
Sbjct: 13662 GEGLKSEPIVARHPFDVPDAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERN 13721
Query: 815 SYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPT 874
S W R N I+ + + EG+ YE RV A+N G+ +PS S+P + + P P
Sbjct: 13722 SLLWKRANKTPIRMRDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPG 13781
Query: 875 HLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDL 934
V +++ +V+L W P+ G L GY VE W+ A + V DL
Sbjct: 13782 KPEVINITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDL 13841
Query: 935 PTGARLLFRVRAHNMAGP-GAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNL 993
G + FR+RA N AG AP +TE + ++ + P + L ++ + K G+ + L
Sbjct: 13842 VEGGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVL 13901
Query: 994 -LIPFQGKPRPQVTWTKEGQPLAGEEVS-IRNSPTDTILFIRAARRVHSGTYQVTVRIEN 1051
I GKP P+ +W+K G+ + +++ I ++PT ++L I+ A R +G Y +T
Sbjct: 13902 NAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPF 13961
Query: 1052 MEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTME 1111
+ + V+D P PP + +++ L W PP + G + + Y ++K + +
Sbjct: 13962 GTKVEHVKVTVLDVPGPPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLL 14021
Query: 1112 WFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPV-----FIPRPGIT 1166
W V E + V +LI GN Y FRV + N G + EPV F P PG
Sbjct: 14022 WTVVSEDIQSCRHVATKLIQGNEYIFRVSAVNHYGKGE--PVQSEPVKMVDRFGP-PGPP 14078
Query: 1167 YEPPNYKALDFSEAPSFTQPLVN-RSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDA 1225
+P + S+ +P+ + S I GY V K + W + D
Sbjct: 14079 EKPEVSNVTKNTATVSWKRPVDDGGSEITGY------HVERREKKSLRWVRAIKTPVSDL 14132
Query: 1226 RFRMFSKQGVLTLEIRKPCPFDGGI 1250
R ++ Q T E R GI
Sbjct: 14133 RCKVTGLQEGSTYEFRVSAENRAGI 14157
Score = 197 bits (500), Expect = 7e-50
Identities = 147/509 (28%), Positives = 216/509 (42%), Gaps = 42/509 (8%)
Query: 644 PPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPE 703
PP++ LD R D I V G +R+ + G P P + W K
Sbjct: 11408 PPEVELDVTCR--DVITVRVGQTIRILARVKGRPEPDITWTK------------------ 11447
Query: 704 DTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVN 763
+ K+L E RV + R ++ A + D G Y ++ KN G Q +
Sbjct: 11448 ----------EGKVLVR-EKRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSGHAQGS 11496
Query: 764 LTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNF 823
V V+D P K++NV +++CT+ WE P +GG I +I+E +K W +
Sbjct: 11497 AIVNVLDRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIVEYRKPNQKGWSIVAS 11556
Query: 824 DLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGP---PSEPTHLAVED 880
D+ + L ++ Y RV A N +G+ P + I P P EP +L + D
Sbjct: 11557 DVTKRLIKA--NLLANNEYYFRVCAENKVGVGPTIETKTPILAINPIDRPGEPENLHIAD 11614
Query: 881 VSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARL 940
T V LKWR P+ G Y VE +G +W +G + T +V
Sbjct: 11615 KGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVENQIY 11674
Query: 941 LFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGK 1000
FRV+ N G V T E V V+E LQ+P L L L + K G+ + L +GK
Sbjct: 11675 EFRVQTKNEGGESDWVKTEE-VVVKEDLQKPVLDLK--LSGVLTVKAGDTIRLEAGVRGK 11731
Query: 1001 PRPQVTWTKEGQPL---AGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKAT 1057
P P+V WTK+ V I + + A+R G Y VT A
Sbjct: 11732 PFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAY 11791
Query: 1058 LVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLE 1117
+ V+DKP P ++L++ D + W PP+D G E+ Y ++K + K M W T
Sbjct: 11792 ATVNVLDKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSA 11851
Query: 1118 HYRRTHCVVPELIIGNGYYFRVFSQNMVG 1146
V LI GN Y FRV ++N +G
Sbjct: 11852 TVLTPGTTVTRLIEGNEYIFRVRAENKIG 11880
Score = 196 bits (498), Expect = 1e-49
Identities = 146/539 (27%), Positives = 227/539 (42%), Gaps = 73/539 (13%)
Query: 635 KIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAP 694
+I V QE P+I LD ++ + V AG K+ L ++G P P + W KA
Sbjct: 7181 EIQAVDTQEAPEIFLDV--KLLAGLTVKAGTKIELPATVTGKPEPKITWTKA-------- 7230
Query: 695 ARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVK 754
++ + + R+ +E +S T+ +++ D G Y +
Sbjct: 7231 ---------------------DMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAV 7269
Query: 755 NPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKK 814
N G + V V+D P PAA I++V +SC + W PP DGG I Y++ER+
Sbjct: 7270 NVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATD 7329
Query: 815 SYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRP---SPASQPFMPIGPPS 871
S W +L+ +++ + +A ++I Y RV A N G+ P SP + + PP
Sbjct: 7330 SEVWHKLS-STVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITAKYQ-FDPPG 7387
Query: 872 EPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILV 931
PT L D++ V+L W P+ G + GY VE +WV + + T+ V
Sbjct: 7388 PPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRV 7447
Query: 932 KDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPV 991
K L + FRV A N+AGPG P +TEP+ +++ + P P
Sbjct: 7448 KGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPP----------------WPPG 7491
Query: 992 NLLIPFQGKPRPQVTWTKEGQPLAG--EEVSIRNSPTDTILFIRAARRV----------- 1038
+ GK ++ WTK E I T T ++R A V
Sbjct: 7492 KPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVPTTQHLLPGLM 7551
Query: 1039 HSGTYQVTVRIENMEDKA--------TLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQ 1090
Y VR N ++ L + + PSPP+ L V + L+W P+
Sbjct: 7552 EGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPE 7611
Query: 1091 DVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSD 1149
G + + Y V+K D + W TV + T C V L G+ Y FRV ++N +G SD
Sbjct: 7612 KDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSD 7670
Score = 196 bits (498), Expect = 1e-49
Identities = 162/633 (25%), Positives = 260/633 (41%), Gaps = 83/633 (13%)
Query: 642 QEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDA 701
QE P++ +D + D +V AG+++R+ I G P P W+ + KA D
Sbjct: 9308 QEEPEVFIDIGAQ--DCLVCKAGSQIRIPAVIKGRPTPKSSWEFD-GKAKKAMKDGVHDI 9364
Query: 702 PEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQ 761
PED ++ET ++ S+ + ++ G Y++T KN G+
Sbjct: 9365 PEDA--------------------QLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKT 9404
Query: 762 VNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRL 821
N VKV+DVP P K+S++ SC + W+ P DGG I GY++E++ W ++
Sbjct: 9405 ANCRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKRTIDGKAWTKV 9464
Query: 822 NFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PIGPPSEPTHLAV 878
N D + ++ Y RV A N G+ P Q PI PP P L +
Sbjct: 9465 NPDC-GSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKI 9523
Query: 879 EDVSDTTVSLKWRPPERVGAGGLDGYSVE---YCPEGCSE--WVAALQGLTEHTSILVKD 933
++ TV L W+PP+ G + Y VE + P G + W + E V+D
Sbjct: 9524 GLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVED 9583
Query: 934 LPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNL 993
L G FRV+A N AG P T P Q RP + L++ ++ + G VN+
Sbjct: 9584 LVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQ----RPDMPPSIDLKEFMEVEEGTNVNI 9639
Query: 994 LIPFQGKPRPQVTWTK-------EGQPLAGEEVSIRNSPTDTI-LFIRAARRVHSGTYQV 1045
+ +G P P +TW K +P+ + + DT L I +RR +G Y +
Sbjct: 9640 VAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTI 9699
Query: 1046 TVRIENMEDKATLVLQVVDKPSPPQD-LRVTDAWGLNVALEWKPPQDVGNTELWGYTVQK 1104
T + L V+ +P PP ++ + L W PP+D G +++ Y ++K
Sbjct: 9700 TAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIEK 9759
Query: 1105 ADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPV--FIPR 1162
+ W V + +P+L+ G+ Y FR+ +QN G + + E
Sbjct: 9760 REANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFSV 9819
Query: 1163 PG----------------ITYEPPNYKA--------LDFSEAPSFTQPLVNRSVIAGYTA 1198
PG + +E P Y L+ + S VNR I T
Sbjct: 9820 PGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMTL 9879
Query: 1199 MLCCAVRGSPKPKISWFKNGLDLGEDARFRMFS 1231
+S+ GL G D +FR+++
Sbjct: 9880 ------------GVSYKVTGLIEGSDYQFRVYA 9900
Score = 195 bits (495), Expect = 3e-49
Identities = 127/403 (31%), Positives = 185/403 (45%), Gaps = 20/403 (4%)
Query: 772 PDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSH 831
P P+ P++S + +DS V W P DGG I GYILE++ K+ RW + N + +L
Sbjct: 18405 PGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLTDLRL 18464
Query: 832 EARRMIEGVVYEMRVYAVNAIGMSRPSP------ASQPFMPIGPPSEPTHLAVEDVSDTT 885
+ EG YE RV A NA G+ PS A P GPPS P V D S ++
Sbjct: 18465 RVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNP---KVTDTSRSS 18521
Query: 886 VSLKWRPPERVGAGGLDGYSVEYCPEGCSEWV-----AALQGLTEHTSILVKDLPTGARL 940
VSL W P G + GY VE EW LQG V L
Sbjct: 18522 VSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQG----KQFTVTKLKENTEY 18577
Query: 941 LFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGK 1000
FR+ A N G G P T V QE ++ P ++L LR+ + + + L + +G+
Sbjct: 18578 NFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRASATLRLFVTIKGR 18637
Query: 1001 PRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVL 1060
P P+V W K + + + I + + T+L I R SG Y +T+ + A + +
Sbjct: 18638 PEPEVKWEK-AEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSGSKTAFVNV 18696
Query: 1061 QVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYR 1120
+V+D PS P +L + + +V L W+PP G ++ Y V+K + + T+ +
Sbjct: 18697 RVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATITNNCT 18756
Query: 1121 RTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRP 1163
+T + L G YYFRV + N G A TT EPV + P
Sbjct: 18757 KTTFRIENLQEGCSYYFRVLASNEYGIGLPAETT-EPVKVSEP 18798
Score = 191 bits (485), Expect = 4e-48
Identities = 129/467 (27%), Positives = 213/467 (45%), Gaps = 18/467 (3%)
Query: 772 PDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSH 831
P P P + + +DS +QW P +GG P++GY LERK++ S W ++N +I +
Sbjct: 16926 PGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQF 16985
Query: 832 EARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PIGPPSEPTHLAVEDVSDTTVSL 888
+A+ + EG+ YE RVYA N +G+ + S S+ ++ P PP P + V+ ++L
Sbjct: 16986 KAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPPGTPEPIMVK---RNEITL 17042
Query: 889 KWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHN 948
+W P G + GY VE W+ A T V L R FRV A N
Sbjct: 17043 QWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKN 17102
Query: 949 MAGP-GAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTW 1007
AG P +T P+T ++ ++ PR+ + R TI GE L GKP P + W
Sbjct: 17103 AAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEW 17162
Query: 1008 TKEGQPL-AGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKAT--LVLQVVD 1064
+ + + I+N+ +L ++ A R+ G Y +R N+ + + ++V+D
Sbjct: 17163 LRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQY--ILRASNVAGSKSFPVNVKVLD 17220
Query: 1065 KPSPPQ-DLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTH 1123
+P PP+ ++VT +L W PP G +++ Y V+K + + W V
Sbjct: 17221 RPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNS 17280
Query: 1124 CVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSF 1183
V +L+ GN Y FR+ + N G + + PV + P + PP K+L+ +
Sbjct: 17281 LKVTKLLEGNEYVFRIMAVNKYGVGEPLESA--PVLMKNPFVLPGPP--KSLEVTNIAKD 17336
Query: 1184 TQPLV-NRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRM 1229
+ + NR G + ++ V + I W K D R R+
Sbjct: 17337 SMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRV 17383
Score = 189 bits (480), Expect = 1e-47
Identities = 125/408 (30%), Positives = 194/408 (47%), Gaps = 15/408 (3%)
Query: 771 VPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELS 830
VP P P ++ DS VQW P DGG ++GY LERK++ S W++LN I +
Sbjct: 15843 VPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTK 15902
Query: 831 HEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PIGPPSEPTHLAVEDVSDTTVS 887
+ + EGV YE RV A N +G+ +PS S+ ++ P PP P + V+ +V+
Sbjct: 15903 FKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAII---VTRNSVT 15959
Query: 888 LKWRPPERVGAGGLDGYSVE--YCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVR 945
L+W+ P G + GY VE PEG W+ A T V L R FRV
Sbjct: 15960 LQWKKPTYDGGSKITGYIVEKKELPEG--RWMKASFTNIIDTHFEVTGLVEDHRYEFRVI 16017
Query: 946 AHNMAGP-GAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQ 1004
A N AG P +T +T ++ + PR+ + + TI GE + GKP P
Sbjct: 16018 ARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPT 16077
Query: 1005 VTWTKEGQPLAG-EEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVV 1063
+ W K Q L+ + I+++ T L ++ A RV SG Y + + E T+ ++V+
Sbjct: 16078 IQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVL 16137
Query: 1064 DKPSPPQ-DLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRT 1122
D+P PP+ + ++ L WKPP G +++ Y V++ + + W V + +
Sbjct: 16138 DRPGPPEGPVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTL 16197
Query: 1123 HCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPP 1170
C V +L+ GN Y FR+ + N G + EPV P + + P
Sbjct: 16198 SCKVTKLLEGNEYTFRIMAVNKYGVGE--PLESEPVVAKNPFVVPDAP 16243
Score = 189 bits (479), Expect = 2e-47
Identities = 129/478 (26%), Positives = 224/478 (46%), Gaps = 24/478 (5%)
Query: 743 KEDEGVYTVTVKNPVG-----EDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAY 797
K +E ++ V N G E + + +P P P+ G++ +QW P
Sbjct: 22709 KNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPES 22768
Query: 798 DGGQPILGYILERKKKKSYRWMRLNFD-LIQELSHEARRMIEGVVYEMRVYAVNAIGMSR 856
DGG I Y++++++KKS RW R+N D ++ + + ++EG Y+ RV AVNA G S
Sbjct: 22769 DGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSE 22828
Query: 857 PSPAS------QPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCP 910
PS AS +P GPPS P V D + ++SL W P G + GY +E
Sbjct: 22829 PSEASNFISCREPSYTPGPPSAPR---VVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQE 22885
Query: 911 EGCSEWVAALQGLT-EHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQ 969
+ +W T +T V DL G + FRV A N+ G + + E ++
Sbjct: 22886 KDTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIE 22945
Query: 970 RPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTI 1029
P L+L L++T+ + G + L++ G+P P +TW+K+G LA + I + + ++
Sbjct: 22946 IPDLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAI-IDTTESYSL 23004
Query: 1030 LFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPP 1089
L + R +G Y + ++ + AT++++V D P P ++V + +V + W+ P
Sbjct: 23005 LIVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIP 23064
Query: 1090 QDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSD 1149
G + Y V+K + + TV +T + L+ G YYFRV +N+ G +
Sbjct: 23065 TIDGGAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGE 23124
Query: 1150 RAATTKEPVFIPRPGITYEPPNYKALDFSEAP---SFTQPLVN-RSVIAGYTAMLCCA 1203
T+ + P + P + +D +++ ++ +PL + S + GY C A
Sbjct: 23125 PCETSDAVLVSEVPLV---PAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKA 23179
Score = 188 bits (477), Expect = 3e-47
Identities = 139/490 (28%), Positives = 224/490 (45%), Gaps = 24/490 (4%)
Query: 700 DAPEDTGDSDEWVF--DKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPV 757
D PED G + + +K+ +T ++ V ++ R+ F V K+ E + V +N
Sbjct: 21182 DVPEDNGGGEITCYSIEKRETSQTNWKM-VCSSVARTTFKVPNLVKDAEYQFRVRAENRY 21240
Query: 758 GEDQVNLTVKVID-----VPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKK 812
G Q ++ ++ +P P P I NV D ++ W+ P YDGG + G+ +E+K+
Sbjct: 21241 GVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKE 21300
Query: 813 KKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQ---PFMPIGP 869
+ S W ++N I + A ++EG+ Y+ RVYA N+ G+S PS S+ P+ P
Sbjct: 21301 RNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDP 21360
Query: 870 PSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSI 929
P P ++ DV+ T++LKW PP R G + GYS+E +G WV
Sbjct: 21361 PGTPDYI---DVTRETITLKWNPPLRDGGSKIVGYSIEK-RQGNERWVRCNFTDVSECQY 21416
Query: 930 LVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTV-QEILQRPRLQLPRHLRQTIQKKVG 988
V L G R FR+ A N G +P + + + + ++ P ++ + K G
Sbjct: 21417 TVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSG 21476
Query: 989 EPVNLLIPFQGKPRPQVTWTKEGQPLAGE-EVSIRNSPTDTILFIRAARRVHSGTYQVTV 1047
E + + QG+P P+VTW K+G + + I + T LF+R A R H G Y V
Sbjct: 21477 ESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEA 21536
Query: 1048 RIENMEDKATLVLQVVDKPSP-PQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKAD 1106
+ + KA + ++V D P +R T+ G + L W P + G + Y ++K +
Sbjct: 21537 KNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRE 21596
Query: 1107 KKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGF-----SDRAATTKEPVFIP 1161
+ W + + +LI GN Y FRV + N G SD +
Sbjct: 21597 TSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPD 21656
Query: 1162 RPGITYEPPN 1171
PGI EP N
Sbjct: 21657 APGIP-EPSN 21665
Score = 185 bits (469), Expect = 3e-46
Identities = 224/932 (24%), Positives = 347/932 (37%), Gaps = 158/932 (16%)
Query: 374 QVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAA 433
+V + ++ E+ A+ KW +N + I SKYI TL I L D A
Sbjct: 6153 RVKEQQEVVFNCEVNTEGAKAKWFRNEEAI-FDSSKYIILQKDLVYTLRIRDAHLDDQAN 6211
Query: 434 YQCVVGGE-----KCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLK 488
Y + K + L V+E + I PL+D M + V F C+V+ +KW K
Sbjct: 6212 YNVSLTNHRGENVKSAANLIVEEEDLRIVEPLKDIETMEKKSVTFWCKVNRLNVTLKWTK 6271
Query: 489 DGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVY 548
+G E+ + YR K +H L I + D G Y + +++AEL++ E E
Sbjct: 6272 NGEEVPFDNRVSYRVDK--YKHMLTIKDCGFPDEGEYIVTAGQDKSVAELLIIEAPTEFV 6329
Query: 549 QSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTP 608
+ + D V D AVF C++S E W +NG+E+ + K G +H+L I D
Sbjct: 6330 EHLEDQTVTEFDDAVFSCQLSREKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDCRL 6389
Query: 609 ADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLR 668
DE +Y+ E A+L E+ ++ + PP+ L+ PG D + + NK +
Sbjct: 6390 DDECEYACGVEDRKSR--ARLFVEEIPVEII---RPPQDILEAPGA--DVVFLAELNKDK 6442
Query: 669 LDVPISGDPAPTVIWQK---AITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRV 725
++V W + + QG+K E + +C+ + R
Sbjct: 6443 VEVQ----------WLRNNMVVVQGDKHQMM------------SEGKIHRLQICDIKPR- 6479
Query: 726 RVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGE 785
D+G Y K+ ++ L AAPKI +
Sbjct: 6480 -------------------DQGEYRFIAKDKEARAKLELA----------AAPKIKTADQ 6510
Query: 786 DSCTVQWEPPAYDGGQPILGYI-LERKKKKSYRWMRLNFDLIQEL-----SHEARRMIEG 839
D D G+P+ + + K W + N L + + R++E
Sbjct: 6511 DLVV--------DVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKTIDTTAEQTSFRILEA 6562
Query: 840 VVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAG 899
+ Y + + I P +L V + D VSL W P G
Sbjct: 6563 KKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDGEVSLAWEEPLTDGGS 6622
Query: 900 GLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGA-RLLFRVRAHNMAGPGAPVTT 958
+ GY VE WV A E V L G LFRV A N G G PV T
Sbjct: 6623 KIIGYVVERRDIKRKTWVLATDR-AESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVET 6681
Query: 959 TEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKE----GQPL 1014
PV R + +P G P+N+ I + +TW G +
Sbjct: 6682 DNPVEA-----RSKYDVP-----------GPPLNVTITDVNRFGVSLTWEPPEYDGGAEI 6725
Query: 1015 AGEEVSIRNSPT---DTILFIRAARR-------VHSGTYQVTVRIENM-----EDKATLV 1059
+ +R+ + DT + +RA V Y VR +N AT
Sbjct: 6726 TNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPF 6785
Query: 1060 LQVVD---KPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVL 1116
++V D +PSPP +L +D +V L+W+PP G + + GY +++ ++ W
Sbjct: 6786 VKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWI--- 6842
Query: 1117 EHYRRTHCVVPELII-------GNGYYFRVFSQNMVGFSDRAAT----TKEPVFIPRPGI 1165
R +VPEL GN Y +RV ++N G SD + T + F+
Sbjct: 6843 ---RCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFV----- 6894
Query: 1166 TYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDA 1225
EP +D S +F L VI + G P+P +W L
Sbjct: 6895 --EP----TMDLS---AFKDGL---EVIVPNPITILVPSTGYPRPTATWCFGDKVLETGD 6942
Query: 1226 RFRMFSKQGVLTLEIRKPCPFDGGIYVCRATN 1257
R +M + L I D GIY + N
Sbjct: 6943 RVKMKTLSAYAELVISPSERSDKGIYTLKLEN 6974
Score = 184 bits (467), Expect = 5e-46
Identities = 128/483 (26%), Positives = 224/483 (46%), Gaps = 20/483 (4%)
Query: 702 PEDTGDSD--EWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVG- 758
PE G S ++ +K+ + +G V+TT + TV + V+ V +N +G
Sbjct: 7610 PEKDGGSPITNYIVEKRDV-RRKGWQTVDTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQ 7668
Query: 759 ------EDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKK 812
ED V L P P A + +V + ++WEPP DGG+PI Y++E+K+
Sbjct: 7669 SDYTEIEDSV-LAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKE 7727
Query: 813 KKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PIGP 869
+ RW++ + + +IEG + +V A N G+ PS ++ P P
Sbjct: 7728 RLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSP 7787
Query: 870 PSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSI 929
PS P L V D +++ W+PPE+ G + GY VE CP G +W+ +
Sbjct: 7788 PSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKF 7847
Query: 930 LVKD-LPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVG 988
V++ + + RVRA N G P +E V ++ +P + L H I+ G
Sbjct: 7848 KVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHDIIVIE---G 7904
Query: 989 EPVNLLIPFQGKPRPQVTWTKEGQPL-AGEEVSIRNSPTDTILFIRAARRVHSGTYQVTV 1047
E +++ +PF+ P P V+W K+G+ + A + ++++N L + + R +G Y +T+
Sbjct: 7905 EKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITL 7964
Query: 1048 RIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADK 1107
+ A++ ++V+ P P +D++ +D + L W+PP+ G T + Y +++ +
Sbjct: 7965 ENKLGSATASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREA 8024
Query: 1108 KTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITY 1167
+ V+ + V +LI Y+FRV + N VG K PV P
Sbjct: 8025 GRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVG-GGEYIELKNPVIAQDPKQPP 8083
Query: 1168 EPP 1170
+PP
Sbjct: 8084 DPP 8086
Score = 183 bits (465), Expect = 8e-46
Identities = 119/406 (29%), Positives = 184/406 (45%), Gaps = 15/406 (3%)
Query: 772 PDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSH 831
P P P ++++ +D VQW P DGG I+GY LE+K+K S W++LN IQ+
Sbjct: 18008 PGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKF 18067
Query: 832 EARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PIGPPSEPTHLAVEDVSDTTVSL 888
+ + EG+ YE +V A N +G+ +PS S+ F+ P PP P + ++ V+L
Sbjct: 18068 KTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAIV---ITRNNVTL 18124
Query: 889 KWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHN 948
KW+ P G + GY VE W+ A T V L R FRV A N
Sbjct: 18125 KWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGLVEDQRYEFRVIARN 18184
Query: 949 MAGP-GAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTW 1007
AG P ++ +T ++ + P L + I GE L +GKP P V W
Sbjct: 18185 AAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVW 18244
Query: 1008 TKEGQPL--AGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDK 1065
+K+G+ L + I+++ T L ++ R G Y + + + ++V+D+
Sbjct: 18245 SKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDR 18304
Query: 1066 PSPPQ-DLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHC 1124
P PP+ L+VT L W PP G + Y ++K + + W V + +
Sbjct: 18305 PGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLSWTQVSTEVQALNY 18364
Query: 1125 VVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPP 1170
V +L+ GN Y FRV + N G + PV P Y+PP
Sbjct: 18365 KVTKLLPGNEYIFRVMAVNKYGIGE--PLESGPVTACNP---YKPP 18405
Score = 183 bits (465), Expect = 8e-46
Identities = 149/599 (24%), Positives = 245/599 (40%), Gaps = 43/599 (7%)
Query: 577 WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKI 636
W K+G+ L +R+ VS V L+I + + D Y A +++ + + I
Sbjct: 18931 WRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSIT-----VPITI 18985
Query: 637 DFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPAR 696
+ R PP +R+D +S D T+ W G +
Sbjct: 18986 IVLDRPGPP-------------------GPIRID-EVSCDSI-TISWNPPEYDGGCQISN 19024
Query: 697 PAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNP 756
+ E T S W + + T ++ TT F V + + Y+
Sbjct: 19025 YIVEKKETT--STTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYS------ 19076
Query: 757 VGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSY 816
E + P P PK+ + + + V W+ P DGG ++GY LE K++ S
Sbjct: 19077 --ESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSI 19134
Query: 817 RWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHL 876
W + N LI + + + EG++YE RVYA N G+ + S + +P P P
Sbjct: 19135 LWSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQP 19194
Query: 877 AVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPT 936
V +++ +VSLKW P G + GY VE W+ + T V +L
Sbjct: 19195 EVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQETYFEVTELTE 19254
Query: 937 GARLLFRVRAHNMA-GPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLI 995
R FRV A N A P +T P+ V++ ++ PR+ + R I K GE + +
Sbjct: 19255 DQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINA 19314
Query: 996 PFQGKPRPQVTWTKEGQPLAGE-EVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMED 1054
G+P P ++W K+G + I ++ T+L ++ R +G Y +T++
Sbjct: 19315 DIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTR 19374
Query: 1055 KATLVLQVVDKPSPPQ-DLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWF 1113
+ +V+DKP PP L + +L W PQ+ G ++ Y V+K + + W
Sbjct: 19375 SVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQEDGGADIDYYIVEKRETSHLAWT 19434
Query: 1114 TVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDR----AATTKEPVFIPRPGITYE 1168
+ T C V +L+ GN Y FRV N G + A +P +P P + E
Sbjct: 19435 ICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLE 19493
Score = 182 bits (462), Expect = 2e-45
Identities = 114/380 (30%), Positives = 178/380 (46%), Gaps = 5/380 (1%)
Query: 771 VPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELS 830
+P P + +++N+ +DS TV W P DGG I+GYI+E++ + RW++ N I +L
Sbjct: 17321 LPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLR 17380
Query: 831 HEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PIGPPSEPTHLAVEDVSDTTVS 887
+ E YE RV A NA G+ PSPA+ + P+ P PT+ + D + +++
Sbjct: 17381 LRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHIVDTTKNSIT 17440
Query: 888 LKWRPPERVGAGGLDGYSVEYCPEGCSEW-VAALQGLTEHTSILVKDLPTGARLLFRVRA 946
L W P G + GY VE C EW + Q T + L RV A
Sbjct: 17441 LAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCA 17500
Query: 947 HNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVT 1006
N G G + V ++ L+ P L L LR+ I + G + IPF+G+P P++T
Sbjct: 17501 LNKVGLGEATSVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGSARIHIPFKGRPTPEIT 17560
Query: 1007 WTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKP 1066
W++E ++V I T L I R +G Y + + + A + ++V+D P
Sbjct: 17561 WSREEGEFT-DKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTP 17619
Query: 1067 SPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVV 1126
PPQ+L V + + L W+PP G ++ Y + K + + V +T V
Sbjct: 17620 GPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKV 17679
Query: 1127 PELIIGNGYYFRVFSQNMVG 1146
L G YYFRV ++N G
Sbjct: 17680 ENLTEGAIYYFRVMAENEFG 17699
Score = 180 bits (456), Expect = 9e-45
Identities = 116/381 (30%), Positives = 183/381 (48%), Gaps = 6/381 (1%)
Query: 772 PDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSH 831
P AP P++ +V ++ +++WE P +DGG I+GY +E+K++ + W++ N E ++
Sbjct: 22344 PSAPTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNY 22403
Query: 832 EARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWR 891
+ ++EG+ Y+ R YA+NA G+S+ S AS+P M P P V DV+ +TVSL W
Sbjct: 22404 KVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQNPVDAPGRPEVTDVTRSTVSLIWS 22463
Query: 892 PPERVGAGGLDGYSVEYCP---EGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHN 948
P G + GY +E P G W+ + V L G FRV A N
Sbjct: 22464 APAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKN 22523
Query: 949 MAGP-GAPVTTTEPVTVQEILQRPRLQLPRHLR-QTIQKKVGEPVNLLIPFQGKPRPQVT 1006
AG +T PVT ++ P+ +L L + + G + L GKP P++
Sbjct: 22524 AAGVISKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIRAGSDLVLDAAVGGKPEPKII 22583
Query: 1007 WTKEGQPL-AGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDK 1065
WTK + L E+VS++ + I+ R SG Y +TV+ + +++++V+D
Sbjct: 22584 WTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLDS 22643
Query: 1066 PSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCV 1125
P P L V+ L W PQ+ G E+ Y V++ + + W V V
Sbjct: 22644 PGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLSYV 22703
Query: 1126 VPELIIGNGYYFRVFSQNMVG 1146
V LI N Y FRV + N G
Sbjct: 22704 VTRLIKNNEYIFRVRAVNKYG 22724
Score = 171 bits (432), Expect = 5e-42
Identities = 157/594 (26%), Positives = 238/594 (40%), Gaps = 72/594 (12%)
Query: 707 DSDEWVFDKKL-LCETEGRVRVETTKDRSIFTV-----EGAEKEDEGVYTVTVKNPVGED 760
D+D+WV K+ + +T RV+ T K + F V G K + + +K+P
Sbjct: 7428 DTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDP---- 7483
Query: 761 QVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMR 820
ID P P P + +VG+ S + W P +DGG I Y++E K + W+R
Sbjct: 7484 --------IDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVR 7535
Query: 821 LNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PIGPPSEPTHLA 877
+ + + H ++EG Y RV AVN G S PS S P + + PPS P L
Sbjct: 7536 VA-EGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLE 7594
Query: 878 VEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTG 937
V +++ T LKW PE+ G + Y VE W + + T V L G
Sbjct: 7595 VINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGW-QTVDTTVKDTKCTVTPLTEG 7653
Query: 938 ARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKV---------- 987
+ +FRV A N G + V ++ P + ++ V
Sbjct: 7654 SLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKND 7713
Query: 988 -GEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSP----TDTILFIRAARRVHSGT 1042
G P+ + + K R W K G+ AG + + R + T+ +RA G
Sbjct: 7714 GGRPIQRYV-IEKKERLGTRWVKAGKT-AGPDCNFRVTDVIEGTEVQFQVRAENEAGVGH 7771
Query: 1043 YQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTV 1102
I ++ED + PSPP DL VTDA ++A+ WKPP+ G + + GY V
Sbjct: 7772 PSEPTEILSIEDPTS-------PPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHV 7824
Query: 1103 QKADKKTMEWFTVLEH------YRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKE 1156
+ T +W V ++ VVP+ Y RV + N +G S E
Sbjct: 7825 EMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPD----KEYVLRVRAVNAIGVS-------E 7873
Query: 1157 PVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFK 1216
P I + +P +D T ++ VI G + R P P +SW K
Sbjct: 7874 PSEISENVVAKDPDCKPTIDLE-----THDII---VIEGEKLSIPVPFRAVPVPTVSWHK 7925
Query: 1217 NGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
+G ++ R M + LE+ K D GIY N G A ++V
Sbjct: 7926 DGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKV 7979
Score = 151 bits (381), Expect = 4e-36
Identities = 127/445 (28%), Positives = 198/445 (44%), Gaps = 36/445 (8%)
Query: 750 TVTVKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILE 809
T + +P+ V + + P AP P I+ V +DSC V W+PPA DGG I Y LE
Sbjct: 24306 TFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLE 24365
Query: 810 RKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPF----- 864
+++KK +W+ + + I+E + +IEG+ YE RV N G S S S+P
Sbjct: 24366 KREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSD 24425
Query: 865 MPIGPP---SEPTHLAVEDVSDTTVSLK-WRPPERVGAGGLDGYSVEYCPEGCSEWVAAL 920
+PI P E +L V S+ T+ K P+ + G E +G +
Sbjct: 24426 VPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQG--KEIIADGLKYRIQEF 24483
Query: 921 QGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLR 980
+G + +++ + +++VRA N G + E+ ++ LP+ L
Sbjct: 24484 KG--GYHQLIIASVTDDDATVYQVRATNQGG------SVSGTASLEVEVPAKIHLPKTLE 24535
Query: 981 --QTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGE----EVSIRNSPTDTILFIRA 1034
+ GE V++ IPF GKP P +TW K GQ L +V + S T +++F
Sbjct: 24536 GMGAVHALRGEVVSIKIPFSGKPDPVITWQK-GQDLIDNNGHYQVIVTRSFT-SLVFPNG 24593
Query: 1035 ARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGN 1094
R +G Y V + D+ T+ L V D P PP+ ++V+D +V L W P G
Sbjct: 24594 VERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGG 24653
Query: 1095 TELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATT 1154
+++ Y V+K W V R T V L Y FRV ++N G S
Sbjct: 24654 SKITNYIVEKCATTAERWLRV-GQARETRYTVINLFGKTSYQFRVIAENKFGLS------ 24706
Query: 1155 KEPVFIPRPGITYEPPNYKALDFSE 1179
+P P IT E +A+++ E
Sbjct: 24707 -KPSEPSEPTITKEDKT-RAMNYDE 24729
Score = 144 bits (364), Expect = 4e-34
Identities = 106/366 (28%), Positives = 162/366 (44%), Gaps = 48/366 (13%)
Query: 640 PRQEPPKI--------HLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGN 691
PR+ P I LD G ++ AG+ +++++P+ G P PTV W+K
Sbjct: 14551 PRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKK------ 14604
Query: 692 KAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTV 751
GD ++L +T+ RV ETT +I + + D G Y +
Sbjct: 14605 --------------GD--------QILKQTQ-RVNFETTATSTILNINECVRSDSGPYPL 14641
Query: 752 TVKNPVGEDQVNLTVKVIDVPDAPAAP-KISNVGEDSCTVQWEPPAYDGGQPILGYILER 810
T +N VGE +T++V D+P P P K V D T W+PP DGG PI Y++E
Sbjct: 14642 TARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEM 14701
Query: 811 KKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGM-----SRPSPASQPFM 865
++ S W+ L +I+ +++A R+ G+ Y+ RV A N G+ S A+ PF
Sbjct: 14702 RQTDSTTWVELATTVIRT-TYKATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFK 14760
Query: 866 PIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTE 925
GPP P V V+ ++++ W P G + GY VE W + L
Sbjct: 14761 VPGPPGTPQ---VTAVTKDSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVP 14817
Query: 926 HTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHL-RQTIQ 984
L G FRV A NMAG P +EP+ + + P +P ++ R T+
Sbjct: 14818 GNIFKSSGLTDGIAYEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHTVT 14877
Query: 985 KKVGEP 990
K +P
Sbjct: 14878 LKWAKP 14883
Score = 142 bits (357), Expect = 3e-33
Identities = 105/345 (30%), Positives = 153/345 (44%), Gaps = 43/345 (12%)
Query: 635 KIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNK-LRLDVPISGDPAPTVIWQKAITQGNKA 693
+I V R + LD G +PD + N RL +PI G PAP+V W+K
Sbjct: 13471 EITVVARDDVVAPDLDLKG-LPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKG------- 13522
Query: 694 PARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTV 753
ED T+ RV VE++ + V +K D G YT+T+
Sbjct: 13523 ---------EDP-------------LATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITL 13560
Query: 754 KNPVGEDQVNLTVKVIDVPDAPAAP-KISNVGEDSCTVQWEPPAYDGGQPILGYILERKK 812
KN G + +++KV+ P P P K V ++ T++W PP DGG I YILE++
Sbjct: 13561 KNVAGTKEGTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRD 13620
Query: 813 KKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGM-----SRPSPASQPF-MP 866
+ +W+ +Q+ + R+ EG+ Y RV A N G+ S P A PF +P
Sbjct: 13621 SVNNKWVTC-ASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVP 13679
Query: 867 IGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEH 926
PP P ++ DV +VSL W P++ G + GY +E+ W A +
Sbjct: 13680 DAPP--PPNIV--DVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRM 13735
Query: 927 TSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRP 971
V L G FRV A N+AG G P +EPV + + P
Sbjct: 13736 RDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPP 13780
Score = 140 bits (352), Expect = 1e-32
Identities = 120/428 (28%), Positives = 177/428 (41%), Gaps = 58/428 (13%)
Query: 375 VSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAY 434
V+ G EL+ D V+W G++++ S K + S G TLT+ L D
Sbjct: 5710 VTAGETATFDCELSYEDIPVEWYLKGKKLEPS-DKVVPRSEGKVHTLTLRDVKLEDAGEV 5768
Query: 435 QCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELT 494
Q K LFVKEPPV T+PLEDQ V G ECEVS E A+VKW K+G E+
Sbjct: 5769 QLTAKDFKTHANLFVKEPPVEFTKPLEDQTVEEGATAVLECEVSRENAKVKWFKNGTEIL 5828
Query: 495 REETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADL 554
+ + KY DG+ L+I++ ED Y + L V +E + + DL
Sbjct: 5829 KSK--KYEIVADGRVRKLVIHDCTPEDIKTYTCDAKDFKTSCNLNVVPPHVEFLRPLTDL 5886
Query: 555 MVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADY 614
V K+ A F+CE+S EN + W K+G E+ + + G V L I+ DEA+Y
Sbjct: 5887 QVREKEMARFECELSRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEY 5946
Query: 615 SFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPIS 674
S E S L +E + F I V + ++L +S
Sbjct: 5947 SC--EVRTARTSGMLTVLEEEAVFTKNLA--------------NIEVSETDTIKLVCEVS 5990
Query: 675 GDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRS 734
P VIW K GD + + ET GR + T +
Sbjct: 5991 -KPGAEVIWYK--------------------GDEE--------IIET-GRYEILTEGRKR 6020
Query: 735 IFTVEGAEKEDEGVYTVTVKNPVGEDQV---NLTVKVIDVP------DAPAAPKISNVGE 785
I ++ A ED G Y + + + +V L + I P + A + ++ +
Sbjct: 6021 ILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLEILEGEKAEFVCSISK 6080
Query: 786 DSCTVQWE 793
+S VQW+
Sbjct: 6081 ESFPVQWK 6088
Score = 137 bits (345), Expect = 7e-32
Identities = 127/511 (24%), Positives = 201/511 (39%), Gaps = 87/511 (17%)
Query: 643 EPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAP 702
+ P LD + D IVV AG L+ I G P P V+W K
Sbjct: 18206 DAPNASLD--PKYKDVIVVHAGETFVLEADIRGKPIPDVVWSK----------------- 18246
Query: 703 EDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQV 762
D K L ET R+ +++T ++ V+ + D G Y + + N G +
Sbjct: 18247 -----------DGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSI 18295
Query: 763 NLTVKVIDVPDAPAAP-KISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRL 821
+TVKV+D P P P K++ V + C + W PP DGG I YI+E+++ W ++
Sbjct: 18296 PITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLSWTQV 18355
Query: 822 NFDLIQELSHEARRMIEGVVYEMRVYAVNAIGM-----SRPSPASQPFMPIGPPSEPTHL 876
+ + +Q L+++ +++ G Y RV AVN G+ S P A P+ P GPPS P
Sbjct: 18356 STE-VQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACNPYKPPGPPSTP--- 18411
Query: 877 AVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPT 936
V ++ ++ + W P G ++GY +E + W + + V L
Sbjct: 18412 EVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLTDLRLRVTGLTE 18471
Query: 937 GARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIP 996
G FRV A N AG G P + + L P G P N +
Sbjct: 18472 GHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPP----------------GPPSNPKVT 18515
Query: 997 FQGKPRPQVTWTKE----GQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENM 1052
+ + W+K G P+ G V ++ + D + + VT EN
Sbjct: 18516 DTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENT 18575
Query: 1053 E--------------DKATLVLQVV--DKPSPPQ-----------DLRVTDAWGLNVALE 1085
E + ATL VV ++ PP+ LR + L V ++
Sbjct: 18576 EYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRASATLRLFVTIK 18635
Query: 1086 WKPPQDVGNTELWGYTVQKADKKTMEWFTVL 1116
+P +V + G +A + FT+L
Sbjct: 18636 GRPEPEVKWEKAEGILTDRAQIEVTSSFTML 18666
Score = 135 bits (340), Expect = 2e-31
Identities = 215/933 (23%), Positives = 349/933 (37%), Gaps = 118/933 (12%)
Query: 378 GHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCV 437
G + EL EV+WL+N + + G K+ S G L I D Y+ +
Sbjct: 6429 GADVVFLAELNKDKVEVQWLRNNMVV-VQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFI 6487
Query: 438 VGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSE-EGAQVKWLKDGVELTRE 496
++ +L + P + T +D +V VG+ + A+ +W K+ L+ +
Sbjct: 6488 AKDKEARAKLELAAAPKIKTAD-QDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTK 6546
Query: 497 ETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMV 556
++ I EA D G Y + AE + K ++V + +L V
Sbjct: 6547 T-----IDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEV 6601
Query: 557 GAKDQAVFKCEVSDENVRGVW---LKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEAD 613
E D V W L +G + ++ I R + D + E
Sbjct: 6602 ---------TETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAESCEFT 6652
Query: 614 YSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPI 673
+ + +G + F + V EP + D P V A +K DVP
Sbjct: 6653 VTGLQKG-----GVEYLFRVSARNRVGTGEP--VETDNP--------VEARSKY--DVP- 6694
Query: 674 SGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSD--EWVFDKK----LLCETEGRVRV 727
G P I T N+ + PE G ++ +V + + + +T VR
Sbjct: 6695 -GPPLNVTI-----TDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRA 6748
Query: 728 ETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLT---VKVIDVPDAPAAP---KIS 781
E VEG E + V +N +G + + VKV D + P+ P S
Sbjct: 6749 EDLSATVTDVVEGQEYS----FRVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSS 6804
Query: 782 NVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVV 841
+ + S ++WEPP DGG PILGYI+ER ++ W+R N L+ EL+++ + +G
Sbjct: 6805 DQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNK 6864
Query: 842 YEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGA-GG 900
Y RV A N G+S PS P EPT D+S L+ P +
Sbjct: 6865 YLYRVSAENKAGVSDPSEILGPLTADDAFVEPTM----DLSAFKDGLEVIVPNPITILVP 6920
Query: 901 LDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTE 960
GY P + W + L + +K L A L+ + G
Sbjct: 6921 STGY-----PRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENR 6975
Query: 961 PVTVQ-----EILQRPRLQLPRHLR-------------QTIQKKVGEPVNLLIPFQGKPR 1002
T+ ++ RP P+ L+ + G P+ + + +
Sbjct: 6976 VKTISGEIDVNVIARP--SAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYV-VEKREV 7032
Query: 1003 PQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIE--NMEDKATLVL 1060
+ TWTK + E ++ + + R G + E NM AT+
Sbjct: 7033 SRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATV-- 7090
Query: 1061 QVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYR 1120
P PP++++ D ++ L W PP++ G + + GY V++ + + +W E
Sbjct: 7091 -----PDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGEPVA 7145
Query: 1121 RTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEA 1180
T V L G Y +RV + N G S + T+E +A+D EA
Sbjct: 7146 ETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEE---------------IQAVDTQEA 7190
Query: 1181 PSF---TQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLT 1237
P + L +V AG L V G P+PKI+W K + L +D R + + T
Sbjct: 7191 PEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKST 7250
Query: 1238 LEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
+ I D G Y+ A N+ G A + V
Sbjct: 7251 VTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNV 7283
Score = 134 bits (338), Expect = 4e-31
Identities = 121/458 (26%), Positives = 200/458 (43%), Gaps = 38/458 (8%)
Query: 708 SDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVK 767
+D+WV K ++ TT ++TV G + E + + +N VG + + +
Sbjct: 23876 TDKWVRHNK--------TQITTT----MYTVTGLVPDAEYQFRIIAQNDVGLSETSPASE 23923
Query: 768 VI------DVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRL 821
+ D P P +I ++ +DS T+QWE P DGG+ ILGY +E ++ W +
Sbjct: 23924 PVVCKDPFDKPSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKS 23983
Query: 822 NFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDV 881
N + I++ ++E YE RV+A N G+SRP + E + E +
Sbjct: 23984 NKERIKDKQFTIGGLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPGIRKE-M 24042
Query: 882 SDTTVSLKWRPPERVGAGGLDGYSVEYCPEG-----CSEWVAALQGLTEHTSILVKDLPT 936
D T L G +++ G ++ + G T +++ ++
Sbjct: 24043 KDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQED 24102
Query: 937 GARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIP 996
++ A N G V T+ + +Q P+ L++ VG + L +
Sbjct: 24103 EG--VYTCIATNEVGE---VETSSKLLLQAT---PQFHPGYPLKEKYYGAVGSTLRLHVM 24154
Query: 997 FQGKPRPQVTWTKEGQPLA--GEEVSIRNSPTDTILFIR-AARRVHSGTYQVTVRIENME 1053
+ G+P P +TW GQ L E ++I N+ T L ++ R+ H+G Y+V +
Sbjct: 24155 YIGRPVPAMTWF-HGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGT 24213
Query: 1054 DKATLVLQVVDKPSPPQDLRVTDAWGLNVA-LEWKPPQDVGNTELWGYTVQKAD-KKTME 1111
A L +++ DKP P V +A N A + WKPP D G + + Y V+K + K+ E
Sbjct: 24214 VDAILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAE 24273
Query: 1112 WFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSD 1149
W V T C + L GYYFRV +QN G SD
Sbjct: 24274 WQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFGISD 24311
Score = 134 bits (337), Expect = 6e-31
Identities = 115/412 (27%), Positives = 167/412 (40%), Gaps = 57/412 (13%)
Query: 654 RIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVF 713
++ + V AG+ +RL+ + G P P V W K DA + T
Sbjct: 11709 KLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKD------------KDATDLTRSP----- 11751
Query: 714 DKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPD 773
RV+++T D S F++ A++ D G Y VT N G TV V+D P
Sbjct: 11752 ----------RVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPG 11801
Query: 774 APAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEA 833
KI +V D CTV W+PP DGG I YILE+ + K W + ++
Sbjct: 11802 PVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTP-GTTV 11860
Query: 834 RRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PIGPPSEPTHLAVEDVSDTTVSLKW 890
R+IEG Y RV A N IG P+ S+P + P P V VS +++ W
Sbjct: 11861 TRLIEGNEYIFRVRAENKIGTGPPT-ESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVW 11919
Query: 891 RPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMA 950
PPE G + GY +E + + WV + + V++L FRV+A N
Sbjct: 11920 NPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEI 11979
Query: 951 GPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKE 1010
G G P + PV ++ ++ P G P N + K + W K
Sbjct: 11980 GIGEPSLPSRPVVAKDPIEPP----------------GPPTNFRVVDTTKHSITLGWGKP 12023
Query: 1011 ----GQPLAGEEVSIR-----NSPTDTILFIRAARRVHSGTYQVTVRIENME 1053
G P+ G V +R SP + AA ++ + VT EN E
Sbjct: 12024 VYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQE 12075
Score = 132 bits (333), Expect = 2e-30
Identities = 101/340 (29%), Positives = 154/340 (45%), Gaps = 19/340 (5%)
Query: 649 LDCPGRIPDT-IVVVAGNKLRLDVPISGDPAPTVIWQKA--ITQGNKAPARPAPDAPEDT 705
+D P I T + V G+++ LD ISG P PT+ W K + + R AP
Sbjct: 8181 IDAPKVILRTSLEVKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRK 8240
Query: 706 GDSDEWVFDKKLLCETEGRVRVETTKD-RSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNL 764
G+ E ++ + R+ ++ +K S V + + D G+Y + V+N G +
Sbjct: 8241 GEVQE---EEPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPC 8297
Query: 765 TVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILER--KKKKSYRWMRLN 822
TV V+D P P ++ + S +WEPP DGG I+ Y LE+ K K W+ +
Sbjct: 8298 TVSVLDTPGPPINFVFEDIRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWIVVT 8357
Query: 823 FDLIQELSHEARRMIEGVVYEMRVYAVNAIG-----MSRPSPASQPFMPIGPPSEPTHLA 877
++ + ++IEG Y RV A N G +S+P A PF GPP P
Sbjct: 8358 -STLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKPLVAKDPF---GPPDAPDKPI 8413
Query: 878 VEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTG 937
VEDV+ ++ +KW P+ G+ L GY +E + W + L V L G
Sbjct: 8414 VEDVTSNSMLVKWNEPKDNGSPIL-GYWLEKREVNSTHWSRVNKSLLNALKANVDGLLEG 8472
Query: 938 ARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPR 977
+FRV A N AGPG ++P T + + P +PR
Sbjct: 8473 LTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIPR 8512
Score = 132 bits (331), Expect = 3e-30
Identities = 116/487 (23%), Positives = 193/487 (39%), Gaps = 56/487 (11%)
Query: 547 VYQSIADLMVGAKDQAVFKCEVSDENVRGV-WLKNGKELVPDSRIKVSHIGRVHKLTIDD 605
+ + + D+ + A C++ + + W + GKEL+ + K+S GR H LT+
Sbjct: 24038 IRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMT 24097
Query: 606 VTPADEADYSFVP--EGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVA 663
DE Y+ + E S+KL Q P+ H P + +
Sbjct: 24098 EEQEDEGVYTCIATNEVGEVETSSKLLL----------QATPQFHPGYP--LKEKYYGAV 24145
Query: 664 GNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEG 723
G+ LRL V G P P + W F + L +
Sbjct: 24146 GSTLRLHVMYIGRPVPAMTW-----------------------------FHGQKLLQNSE 24176
Query: 724 RVRVETTKDRSIFTVEGAEKEDE-GVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAP-KIS 781
+ +E T+ + ++ +++ G Y V + N G L V++ D PD P P I
Sbjct: 24177 NITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIE 24236
Query: 782 NVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVV 841
+ ++S + W+PPA DGG I Y++E+ + K +L I + + E
Sbjct: 24237 ALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAG 24296
Query: 842 YEMRVYAVNAIGMSRPSPAS------QPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPER 895
Y RV A N G+S P S PF G P +PT AV D+ V + W+PP
Sbjct: 24297 YYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAV--TKDSCV-VAWKPPAS 24353
Query: 896 VGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAP 955
G + Y +E + ++W++ T VK+L G FRV+ N+ G
Sbjct: 24354 DGGAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEW 24413
Query: 956 VTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLA 1015
+EP+T + + LR + + L+ G P+P V W ++G+ +
Sbjct: 24414 SEISEPITPKSDVPIQAPHFKEELR-NLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEII 24472
Query: 1016 GEEVSIR 1022
+ + R
Sbjct: 24473 ADGLKYR 24479
Score = 131 bits (329), Expect = 5e-30
Identities = 95/310 (30%), Positives = 133/310 (42%), Gaps = 39/310 (12%)
Query: 657 DTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKK 716
+T V+AG L++DVP G P P V W K D
Sbjct: 15658 NTFTVLAGEDLKVDVPFIGRPTPAVTWHK----------------------------DNV 15689
Query: 717 LLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPA 776
L +T RV E+T++ S+ T++ A +ED G Y V + N GE L V V+D P P
Sbjct: 15690 PLKQTT-RVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPPT 15748
Query: 777 AP-KISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARR 835
P K+ V DS T+ W PP YDGG I YI+E++ + W ++ + + +A R
Sbjct: 15749 GPVKMDEVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTWQIVSAT-VARTTIKACR 15807
Query: 836 MIEGVVYEMRVYAVNAIGMS-----RPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKW 890
+ G Y+ R+ A N G S P+ A PF GPP P V S ++ ++W
Sbjct: 15808 LKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPV---VTLSSRDSMEVQW 15864
Query: 891 RPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMA 950
P G + GY +E WV + T L G FRV A N+
Sbjct: 15865 NEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIV 15924
Query: 951 GPGAPVTTTE 960
G G P +E
Sbjct: 15925 GIGKPSKVSE 15934
Score = 130 bits (328), Expect = 6e-30
Identities = 94/317 (29%), Positives = 141/317 (44%), Gaps = 37/317 (11%)
Query: 643 EPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAP 702
+PP+I +D + DTIVV AG ++D I G P PT+ W K
Sbjct: 16042 DPPRISMD--PKYKDTIVVHAGESFKVDADIYGKPIPTIQWIK----------------- 16082
Query: 703 EDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQV 762
GD + R+ +++T + +V+ A + D G Y + KN GE V
Sbjct: 16083 ---GDQE---------LSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSV 16130
Query: 763 NLTVKVIDVPDAPAAP-KISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRL 821
+ VKV+D P P P IS V + CT+ W+PP DGG I+ YI+ER++ W +
Sbjct: 16131 TVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVV 16190
Query: 822 NFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGP---PSEPTHLAV 878
+ + +Q LS + +++EG Y R+ AVN G+ P S+P + P P P V
Sbjct: 16191 DAN-VQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPL-ESEPVVAKNPFVVPDAPKAPEV 16248
Query: 879 EDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGA 938
V+ ++ + W P G + GY +E + W + L + V L
Sbjct: 16249 TTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENH 16308
Query: 939 RLLFRVRAHNMAGPGAP 955
FRV A N AG P
Sbjct: 16309 DYEFRVSAENAAGLSEP 16325
Score = 128 bits (321), Expect = 4e-29
Identities = 99/421 (23%), Positives = 172/421 (40%), Gaps = 64/421 (15%)
Query: 644 PPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPE 703
PP+I L + + V AG + LD + G P PTV W+K
Sbjct: 12795 PPRIDLSVA--MKSLLTVKAGTNVCLDATVFGKPMPTVSWKK------------------ 12834
Query: 704 DTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVE--GAEKEDEGVYTVTVKNPVGEDQ 761
D LL EG ++ R++ T+E ++D G YT+T +N G
Sbjct: 12835 ----------DGTLLKPAEG---IKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKS 12881
Query: 762 VNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRL 821
+ +KV+D P PA+ KI+ + D + WEPP DGG I YI+++++ W ++
Sbjct: 12882 ATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNWAQV 12941
Query: 822 NFDLIQELSHEARRMIEGVVYEMRVYAVNAIGM-----SRPSPASQPFMPIGPPSEPTHL 876
+ + S ++IEG Y+ R+ A N G+ + P+ A P+ P G P
Sbjct: 12942 S-ATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPP--- 12997
Query: 877 AVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPT 936
+ +++ +++ W+PP G + GY +E W + ++ L
Sbjct: 12998 VISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQE 13057
Query: 937 GARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIP 996
G FRV A N AGPG P ++ ++ P G P +
Sbjct: 13058 GTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPP----------------GPPAFPKVY 13101
Query: 997 FQGKPRPQVTWTKE----GQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENM 1052
+ ++W K G P+ G V ++ + +D + + + ++VT +E+
Sbjct: 13102 DTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMEDT 13161
Query: 1053 E 1053
+
Sbjct: 13162 Q 13162
Score = 127 bits (320), Expect = 5e-29
Identities = 107/389 (27%), Positives = 163/389 (41%), Gaps = 50/389 (12%)
Query: 365 FQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTIS 424
F K LE V +G L E++ +A+VKW KNG EI + KY + G R L I
Sbjct: 5790 FTKPLEDQ-TVEEGATAVLECEVSRENAKVKWFKNGTEI-LKSKKYEIVADGRVRKLVIH 5847
Query: 425 QCSLADDAAYQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQV 484
C+ D Y C K S L V P V RPL D V + FECE+S E A+V
Sbjct: 5848 DCTPEDIKTYTCDAKDFKTSCNLNVVPPHVEFLRPLTDLQVREKEMARFECELSRENAKV 5907
Query: 485 KWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKK 544
KW KDG E+ + + KY G L+IN+ +L+D Y+ + L V E++
Sbjct: 5908 KWFKDGAEIKKGK--KYDIISKGAVRILVINKCLLDDEAEYSCEVRTARTSGMLTVLEEE 5965
Query: 545 LEVYQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTID 604
+++A++ V D CEVS +W K +E++ R ++ GR L I
Sbjct: 5966 AVFTKNLANIEVSETDTIKLVCEVSKPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQ 6025
Query: 605 DVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAG 664
+ D +Y+ + K+H E+ +F+ + P + ++ G
Sbjct: 6026 NAHLEDAGNYNCRLPSSRTDGKVKVH--ELAAEFISK--------------PQNLEILEG 6069
Query: 665 NKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGR 724
K IS + P V W++ D ++GD + + D G+
Sbjct: 6070 EKAEFVCSISKESFP-VQWKR-------------DDKTLESGDKYDVIAD--------GK 6107
Query: 725 VRVETTKDRSIFTVEGAEKEDEGVYTVTV 753
RV KD ++ +D G Y V V
Sbjct: 6108 KRVLVVKDATL--------QDMGTYVVMV 6128
Score = 127 bits (318), Expect = 9e-29
Identities = 91/356 (25%), Positives = 152/356 (42%), Gaps = 39/356 (10%)
Query: 643 EPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAP 702
E P+I +D R DTIVV AG RL+ + G P PT+ W +
Sbjct: 17124 ELPRISMDPKFR--DTIVVNAGETFRLEADVHGKPLPTIEWLRG---------------- 17165
Query: 703 EDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQV 762
DK++ E R ++ T +++ V+ A + D G Y + N G
Sbjct: 17166 -----------DKEI--EESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSF 17212
Query: 763 NLTVKVIDVPDAPAAP-KISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRL 821
+ VKV+D P P P +++ V + C++ W PP DGG I Y++E+++ W +
Sbjct: 17213 PVNVKVLDRPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISHYVVEKRETSRLAWTVV 17272
Query: 822 NFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM--PIGPPSEPTHLAVE 879
+++ S + +++EG Y R+ AVN G+ P ++ M P P P L V
Sbjct: 17273 ASEVVTN-SLKVTKLLEGNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVT 17331
Query: 880 DVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGAR 939
+++ ++++ W P+ G + GY VE W+ + + V L
Sbjct: 17332 NIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHE 17391
Query: 940 LLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKV----GEPV 991
FRV A N AG G P T + + +P H+ T + + G+P+
Sbjct: 17392 YEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPI 17447
Score = 127 bits (318), Expect = 9e-29
Identities = 97/336 (28%), Positives = 144/336 (42%), Gaps = 38/336 (11%)
Query: 640 PRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAP 699
P+ EP D G I AG+ +DVPISG PAP V W+
Sbjct: 22144 PQIEPTA---DLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWK--------------- 22185
Query: 700 DAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGE 759
++ L ET+ RV + TTKDR+ TV+ + + D G Y +T++N G
Sbjct: 22186 -------------LEEMRLKETD-RVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGV 22231
Query: 760 DQVNLTVKVIDVPDAPAAP-KISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRW 818
++TV VI P P ++S+V +SC + W P GG I YI+E+++ + W
Sbjct: 22232 KTFSVTVVVIGRPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAW 22291
Query: 819 MRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PIGPPSEPTH 875
+N ++ + + + + Y RV + N G+S+P S P + P PPS PT
Sbjct: 22292 QLVNSS-VKRTQIKVTHLTKYMEYSFRVSSENRFGVSKPLE-SAPIIAEHPFVPPSAPTR 22349
Query: 876 LAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLP 935
V VS +S++W P G + GY VE WV + + V L
Sbjct: 22350 PEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLV 22409
Query: 936 TGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRP 971
G FR A N AG + P+ Q + P
Sbjct: 22410 EGLEYQFRTYALNAAGVSKASEASRPIMAQNPVDAP 22445
Score = 124 bits (312), Expect = 4e-28
Identities = 103/421 (24%), Positives = 167/421 (39%), Gaps = 57/421 (13%)
Query: 643 EPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAP 702
E PKI +D + DT+++ AG RL+ +SG P PT+ W K
Sbjct: 14960 EAPKIKVDV--KFKDTVILKAGEAFRLEADVSGRPPPTMEWSK----------------- 15000
Query: 703 EDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQV 762
D K L E ++ ++ + + + + D G YT+T NP G +
Sbjct: 15001 -----------DGKEL-EGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGGFAKH 15048
Query: 763 NLTVKVIDVPDAPAAP-KISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRL 821
VKV+D P P P ++ V + C + W PP DGG I YI+++++ W +
Sbjct: 15049 IFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNV 15108
Query: 822 NFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PIGPPSEPTHLAV 878
+ +Q + ++++G Y RV AVN G+ P S+P + P GPP P + V
Sbjct: 15109 ASE-VQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPL-ESEPVLAVNPYGPPDPPKNPEV 15166
Query: 879 EDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGA 938
++ ++ + W P+ G + Y VE + W+ + V L G
Sbjct: 15167 TTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGH 15226
Query: 939 RLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQ 998
FR+ A N AG AP T+ + + +P G P N +
Sbjct: 15227 EYEFRIMAENAAGISAPSPTSPFYKACDTVFKP----------------GPPGNPRVLDT 15270
Query: 999 GKPRPQVTWTKE----GQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMED 1054
+ + W K G + G V I D + + + +Y +T EN E
Sbjct: 15271 SRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKATSYTITGLTENQEY 15330
Query: 1055 K 1055
K
Sbjct: 15331 K 15331
Score = 123 bits (309), Expect = 1e-27
Identities = 133/548 (24%), Positives = 211/548 (38%), Gaps = 60/548 (10%)
Query: 739 EGAEKEDEGVYTVTVKNPVGEDQVNLTVKVID------VPDAPAAPKISNVGEDSCTVQW 792
EG E E Y V +N G + T +I +P P+ PKI + G+ + T+ W
Sbjct: 19552 EGCEYE----YRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAW 19607
Query: 793 EPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAI 852
P +DGG PI GY +E KK W + + ++ + + G Y RV +VN +
Sbjct: 19608 VKPLFDGGAPITGYTVEYKKSDDTDW-KTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKV 19666
Query: 853 GMSRPSPASQPFMPIGPPSEPTHLAVEDVSDT-----------TVSLKWRPPERV--GAG 899
G S PS +S P + EP ++ T TV + RP V
Sbjct: 19667 GASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKP 19726
Query: 900 GLDGYSVEYCPEGCSEWVAALQGLTEHTS----ILVKDLPTGARLLFRVRAHNMAGPGAP 955
D + Y S ++ + S + ++++ + A L V+ + GP
Sbjct: 19727 DTDLRTRAYVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGPPTN 19786
Query: 956 VTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLA 1015
+T + +L +P + G PV + + + W
Sbjct: 19787 ITVQDVTKESAVLS---WDVP-------ENDGGAPVKNY-HIEKREASKKAWVSVTNNCN 19835
Query: 1016 GEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVT 1075
+ N I + R + G V + E E +++ +KPSPP+ L VT
Sbjct: 19836 RLSYKVTNLQEGAIYYFRVSGENEFG---VGIPAETKEG-----VKITEKPSPPEKLGVT 19887
Query: 1076 DAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGY 1135
+V+L W P+ G + + Y V+ +K W + TH VV L + Y
Sbjct: 19888 SISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQKNWVKCAVA-KSTHHVVSGLRENSEY 19946
Query: 1136 YFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAG 1195
+FRVF++N G SD PV I EPP +D PS T V AG
Sbjct: 19947 FFRVFAENQAGLSDPRELLL-PVLIKEQ---LEPPE---IDMKNFPSHTV-----YVRAG 19994
Query: 1196 YTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRA 1255
+ + G P PK++ ++G+ L RF LT+ +++ D G Y A
Sbjct: 19995 SNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITA 20054
Query: 1256 TNLQGEAR 1263
N G +
Sbjct: 20055 ANSSGTTK 20062
Score = 121 bits (304), Expect = 4e-27
Identities = 84/310 (27%), Positives = 131/310 (42%), Gaps = 39/310 (12%)
Query: 657 DTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKK 716
+T + AG L++++P+ G P P + W K D +
Sbjct: 17822 NTYSIQAGEDLKIEIPVIGRPRPNISWVK----------------------------DGE 17853
Query: 717 LLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPA 776
L +T RV VE T ++ ++ K+D G YTVT N G NL+V V++ P P
Sbjct: 17854 PLKQTT-RVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGPPV 17912
Query: 777 AP-KISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARR 835
P + V D + WEPPAY GG I YI+E++ + W ++ + + + +
Sbjct: 17913 GPVRFDEVSADFVVISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVSAT-VARTTIKITK 17971
Query: 836 MIEGVVYEMRVYAVNAIGMSRPSPASQ-----PFMPIGPPSEPTHLAVEDVSDTTVSLKW 890
+ G Y+ R++A N G S P + PF GPP P V +S + ++W
Sbjct: 17972 LKTGTEYQFRIFAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPF---VTSISKDQMLVQW 18028
Query: 891 RPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMA 950
P G + GY +E + WV + + T L G F+V A N+
Sbjct: 18029 HEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIV 18088
Query: 951 GPGAPVTTTE 960
G G P +E
Sbjct: 18089 GIGKPSKVSE 18098
Score = 121 bits (304), Expect = 4e-27
Identities = 89/349 (25%), Positives = 156/349 (44%), Gaps = 15/349 (4%)
Query: 738 VEGAEKEDEGVYTVTVKNPVG-----EDQVNLTVKV-IDVPDAPA-APKISNVGEDSCTV 790
V+G ++ E + V+ +N G + + +T K ++ P+ P+ P++ +V + S ++
Sbjct: 23792 VKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSL 23851
Query: 791 QWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVN 850
W P DGG + GY +ERK+ + +W+R N I + ++ Y+ R+ A N
Sbjct: 23852 SWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQFRIIAQN 23911
Query: 851 AIGMSRPSPASQPFM---PIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVE 907
+G+S SPAS+P + P PS+P L + +S +V+L+W PE G + GY VE
Sbjct: 23912 DVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVE 23971
Query: 908 YCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEI 967
Y G S W + + + + L FRV A N G P T ++++
Sbjct: 23972 YRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYEFRVFAENETGLSRPRRTA--MSIKTK 24029
Query: 968 LQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPL-AGEEVSIRNSPT 1026
L R + + K+GE L G+P P + W + G+ L + + +
Sbjct: 24030 LTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGR 24089
Query: 1027 DTILFIRAARRVHSGTYQ--VTVRIENMEDKATLVLQVVDKPSPPQDLR 1073
L + + G Y T + +E + L+LQ + P L+
Sbjct: 24090 THTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLK 24138
Score = 121 bits (303), Expect = 5e-27
Identities = 99/388 (25%), Positives = 160/388 (41%), Gaps = 45/388 (11%)
Query: 480 EGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELI 539
E Q KW+ E RE F + +G + + L ++ + +++
Sbjct: 24368 EKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSDVP 24427
Query: 540 VQEKKLEVYQSIADLMVGAKDQAVFKCEVSDENVRGV-WLKNGKELVPDS-RIKVSHI-G 596
+Q + + + +L V + A C+V+ V W + GKE++ D + ++ G
Sbjct: 24428 IQAPHFK--EELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKG 24485
Query: 597 RVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIP 656
H+L I VT D Y ++S +EV++ P KIHL
Sbjct: 24486 GYHQLIIASVTDDDATVYQVRATNQGGSVSGTAS-LEVEV-------PAKIHLPKTLEGM 24537
Query: 657 DTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKK 716
+ + G + + +P SG P P + WQK +
Sbjct: 24538 GAVHALRGEVVSIKIPFSGKPDPVITWQKG-----------------------------Q 24568
Query: 717 LLCETEGRVRVETTKD-RSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAP 775
L + G +V T+ S+ G E++D G Y V KN G DQ + + V DVPD P
Sbjct: 24569 DLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPP 24628
Query: 776 AAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARR 835
K+S+V DS + W PA DGG I YI+E+ + RW+R+ +E +
Sbjct: 24629 RGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVG--QARETRYTVIN 24686
Query: 836 MIEGVVYEMRVYAVNAIGMSRPSPASQP 863
+ Y+ RV A N G+S+PS S+P
Sbjct: 24687 LFGKTSYQFRVIAENKFGLSKPSEPSEP 24714
Score = 120 bits (301), Expect = 8e-27
Identities = 94/330 (28%), Positives = 139/330 (42%), Gaps = 42/330 (12%)
Query: 644 PPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPE 703
PPK LD D + + AG+ L LD + G P P +IW K
Sbjct: 22546 PPKAELDARLH-GDLVTIRAGSDLVLDAAVGGKPEPKIIWTKG----------------- 22587
Query: 704 DTGDSDEWVFDKKL-LCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQV 762
DK+L LCE +V ++ T R+ ++ ++ D G YT+TVKN G V
Sbjct: 22588 ----------DKELDLCE---KVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAV 22634
Query: 763 NLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLN 822
++ VKV+D P +S V ++ CT+ W P DGG I YI+ER++ W+ +
Sbjct: 22635 SVMVKVLDSPGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLNWVIVE 22694
Query: 823 FDLIQELSHEARRMIEGVVYEMRVYAVNAIG-----MSRPSPASQPFMPIGPPSEPTHLA 877
+ LS+ R+I+ Y RV AVN G S P A F PP P +
Sbjct: 22695 GE-CPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVG 22753
Query: 878 VEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEH-TSILVKDLPT 936
+ ++W PE G + Y V+ + W + + T + V L
Sbjct: 22754 ---TGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLME 22810
Query: 937 GARLLFRVRAHNMAGPGAPVTTTEPVTVQE 966
G FRV A N AG P + ++ +E
Sbjct: 22811 GCDYQFRVTAVNAAGNSEPSEASNFISCRE 22840
Score = 119 bits (298), Expect = 2e-26
Identities = 80/274 (29%), Positives = 134/274 (48%), Gaps = 6/274 (2%)
Query: 365 FQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTIS 424
F KL+ V K I L E++ DA VKW K+G+EI+ S + I ++ G KR L +
Sbjct: 5523 FTGKLQDYTGVEKDEVI-LQCEISKADAPVKWFKDGKEIKPSKNAVI-KADGKKRMLILK 5580
Query: 425 QCSLADDAAYQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQV 484
+ +D Y C G +K S +L +++ + + RPL VM + FE E+SE+
Sbjct: 5581 KALKSDIGQYTCDCGTDKTSGKLDIEDREIKLVRPLHSVEVMETETARFETEISEDDIHA 5640
Query: 485 KWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKK 544
W G L +T K++G+ H L+++ L+ G + ++ A L V+ +
Sbjct: 5641 NWKLKGEALL--QTPDCEIKEEGKIHSLVLHNCRLDQTGGVDFQAANVKSSAHLRVKPRV 5698
Query: 545 LEVYQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTID 604
+ + + + D+ V A + A F CE+S E++ W GK+L P ++ G+VH LT+
Sbjct: 5699 IGLLRPLKDVTVTAGETATFDCELSYEDIPVEWYLKGKKLEPSDKVVPRSEGKVHTLTLR 5758
Query: 605 DVTPADEADYSFVPEGFACNLSAKLHFMEVKIDF 638
DV D + + F + A L E ++F
Sbjct: 5759 DVKLEDAGEVQLTAKDFKTH--ANLFVKEPPVEF 5790
Score = 119 bits (297), Expect = 2e-26
Identities = 81/306 (26%), Positives = 131/306 (42%), Gaps = 39/306 (12%)
Query: 661 VVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCE 720
V G L+++VPISG P PT+ W K D L +
Sbjct: 16744 VQVGQDLKIEVPISGRPKPTITWTK----------------------------DGLPLKQ 16775
Query: 721 TEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAP-K 779
T R+ V + D + +++ K+D G Y +TV N VG+ ++ + +D PD P P K
Sbjct: 16776 TT-RINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVK 16834
Query: 780 ISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEG 839
+V +S T+ W PP Y GG I YI++++ + W ++ + + + ++ G
Sbjct: 16835 FDDVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSAT-VARTTLKVTKLKTG 16893
Query: 840 VVYEMRVYAVNAIGMS-----RPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPE 894
Y+ R++A N G S P A P+ GPP P A+ S ++ ++W P
Sbjct: 16894 TEYQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAI---SKDSMVIQWHEPV 16950
Query: 895 RVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGA 954
G + GY +E W + + T ++L G FRV A N+ G G
Sbjct: 16951 NNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGK 17010
Query: 955 PVTTTE 960
+E
Sbjct: 17011 ASKNSE 17016
Score = 118 bits (295), Expect = 4e-26
Identities = 111/440 (25%), Positives = 189/440 (42%), Gaps = 60/440 (13%)
Query: 395 KWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCSTELFVKEPPV 454
KWLKNG EI+ S K + +L I D A Y V G + L+V+ +
Sbjct: 2954 KWLKNGVEIK-STDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHI 3012
Query: 455 LITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLII 514
+ ++D V+ +R FECEVSE V+W+KD EL + T + + +K+ H L+I
Sbjct: 3013 EFRKHIKDIKVLEKKRAMFECEVSEPDITVQWMKDDQEL--QITDRIKIQKEKYVHRLLI 3070
Query: 515 NEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDENVR 574
+ DAG Y + G + A+L V+ + + + ++ V K +AV + EV++++V
Sbjct: 3071 PSTRMSDAGKYTVVAGGNVSTAKLFVEGRDVRIRSIKKEVQVIEKQRAVVEFEVNEDDVD 3130
Query: 575 GVWLKNGKEL--VPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFM 632
W K+G E+ R K R+H++ I + +D +Y+FV +++
Sbjct: 3131 AHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVTL----- 3185
Query: 633 EVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNK 692
+V EPP++ + + V +G R ISG P P + W K
Sbjct: 3186 -----YVNAPEPPQVLQEL-----QPVTVQSGKPARFCAVISGRPQPKISWYK------- 3228
Query: 693 APARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVT 752
+E + C+ + ++ ++ +E A ED VYT
Sbjct: 3229 ----------------EEQLLSTGFKCKF-----LHDGQEYTLLLIE-AFPEDAAVYTCE 3266
Query: 753 VKNPVG--EDQVNLTVKVIDV--PDAPA---APKISNVGEDSCTVQWEPPAY----DGGQ 801
KN G +L+V+V +V PD P I +D+ T + +P + G
Sbjct: 3267 AKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTD 3326
Query: 802 PILGYILERKKKKSYRWMRL 821
+ + + KK K R+ R+
Sbjct: 3327 LKVSWYSKDKKIKPSRFFRM 3346
Score = 118 bits (295), Expect = 4e-26
Identities = 86/275 (31%), Positives = 130/275 (47%), Gaps = 7/275 (2%)
Query: 365 FQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTIS 424
F KL V K +I L E++ D VKW K+G+EI S KY ++ G +R L I
Sbjct: 5168 FTVKLHDKTAVEKD-EITLKCEVSK-DVPVKWFKDGEEIVPS-PKYSIKADGLRRILKIK 5224
Query: 425 QCSLADDAAYQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQV 484
+ L D Y C G +K + V+ + + +PL V VG+ FE E+SE
Sbjct: 5225 KADLKDKGEYVCDCGTDKTKANVTVEARLIKVEKPLYGVEVFVGETAHFEIELSEPDVHG 5284
Query: 485 KWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKK 544
+W G LT + +DG++H LI++ L G + + ++ A L V+E
Sbjct: 5285 QWKLKGQPLTASPDCE--IIEDGKKHILILHNCQLGMTGEVSFQAANAKSAANLKVKELP 5342
Query: 545 LEVYQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTID 604
L ++D+ V KD+A F+CEVS E WLK +E+ D R ++ G H + I
Sbjct: 5343 LIFITPLSDVKVFEKDEAKFECEVSREPKTFRWLKGTQEITGDDRFELIKDGTKHSMVIK 5402
Query: 605 DVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFV 639
DEA Y F E + S KL +++ F+
Sbjct: 5403 SAAFEDEAKYMFEAED--KHTSGKLIIEGIRLKFL 5435
Score = 117 bits (294), Expect = 5e-26
Identities = 82/248 (33%), Positives = 119/248 (47%), Gaps = 8/248 (3%)
Query: 386 ELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCST 445
E++ + WLKNG EI+MS K+ G L I S D A Y V G ++ S
Sbjct: 2858 EVSHFNVPSMWLKNGVEIEMS-EKFKIVVQGKLHQLIIMNTSTEDSAEYTFVCGNDQVSA 2916
Query: 446 ELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKK 505
L V P++IT L+D + FE V+ EG KWLK+GVE+ + + R KK
Sbjct: 2917 TLTVT--PIMITSMLKDINAEEKDTITFEVTVNYEGISYKWLKNGVEIKSTDKCQMRTKK 2974
Query: 506 DGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFK 565
H L I DA Y + A L V+ + +E + I D+ V K +A+F+
Sbjct: 2975 --LTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIEFRKHIKDIKVLEKKRAMFE 3032
Query: 566 CEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNL 625
CEVS+ ++ W+K+ +EL RIK+ VH+L I +D Y+ V G N+
Sbjct: 3033 CEVSEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVAGG---NV 3089
Query: 626 SAKLHFME 633
S F+E
Sbjct: 3090 STAKLFVE 3097
Score = 117 bits (294), Expect = 5e-26
Identities = 76/266 (28%), Positives = 117/266 (43%), Gaps = 7/266 (2%)
Query: 370 EPAY--QVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCS 427
+P Y +V G +EL++ D +W GQ + S I E G K L + C
Sbjct: 5258 KPLYGVEVFVGETAHFEIELSEPDVHGQWKLKGQPLTASPDCEIIED-GKKHILILHNCQ 5316
Query: 428 LADDAAYQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWL 487
L K + L VKE P++ PL D V +FECEVS E +WL
Sbjct: 5317 LGMTGEVSFQAANAKSAANLKVKELPLIFITPLSDVKVFEKDEAKFECEVSREPKTFRWL 5376
Query: 488 KDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEV 547
K E+T ++ F+ KDG +H ++I A ED Y +LI++ +L+
Sbjct: 5377 KGTQEITGDDRFE--LIKDGTKHSMVIKSAAFEDEAKYMFEAEDKHTSGKLIIEGIRLKF 5434
Query: 548 YQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVT 607
+ D+ K+ AVF E+S +N+R W KN + L + + G+ H +T D++
Sbjct: 5435 LTPLKDVTAKEKESAVFTVELSHDNIRVKWFKNDQRLHTTRSVSMQDEGKTHSITFKDLS 5494
Query: 608 PADEADYSFVPEGFACNLSAKLHFME 633
D + E + AKL +E
Sbjct: 5495 IDDTSQIRV--EAMGMSSEAKLTVLE 5518
Score = 115 bits (289), Expect = 2e-25
Identities = 84/310 (27%), Positives = 138/310 (44%), Gaps = 12/310 (3%)
Query: 360 KKSTAFQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKR 419
K+ F ++L+ K E ++ +VKW K+G E+ G KY S
Sbjct: 2125 KQLITFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVH-EGDKYRMHSDRKVH 2183
Query: 420 TLTISQCSLADDAAYQCVVGGE---KCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECE 476
L+I +D Y CV+ + K + +L V+ V + L+D V E EC
Sbjct: 2184 FLSILTIDTSDAEDYSCVLVEDENVKTTAKLIVEGAVVEFVKELQDIEVPESYSGELECI 2243
Query: 477 VSEEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALA 536
VS E + KW + VEL + KY R +L + + ED G Y+ G +
Sbjct: 2244 VSPENIEGKWYHNDVEL--KSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGKKTTC 2301
Query: 537 ELIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIG 596
+L ++ + + + Q ++D V D + +VS E+V GVW+K+G+E+ P R+ +
Sbjct: 2302 KLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHIVIDK 2361
Query: 597 RVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQ-----EPPKIHLDC 651
+ H L I+D+T D +YSF + S ++ V + P + E K L+C
Sbjct: 2362 QSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVDV-ITPLKDVNVIEGTKAVLEC 2420
Query: 652 PGRIPDTIVV 661
+PD V
Sbjct: 2421 KVSVPDVTSV 2430
Score = 114 bits (285), Expect = 6e-25
Identities = 99/408 (24%), Positives = 161/408 (39%), Gaps = 59/408 (14%)
Query: 649 LDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDS 708
+D P + + AG ++L ISG PAPT+ W K
Sbjct: 20375 IDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKD---------------------- 20412
Query: 709 DEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKV 768
DK+L +T V VE T D + ++ A++ + G Y + ++N +G + V++
Sbjct: 20413 -----DKEL--QTNALVCVENTTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQI 20465
Query: 769 IDVPDAPAAP-KISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQ 827
+D P P P + V + T+ W PPA DGG I YI+E+++ W ++ + ++
Sbjct: 20466 LDKPGPPGGPIEFKTVTAEKITLLWRPPADDGGAKITHYIVEKRETSRVVWSMVS-EHLE 20524
Query: 828 ELSHEARRMIEGVVYEMRVYAVNAIGMSRPSP-----ASQPFMPIGPPSEPTHLAVEDVS 882
E ++I+G Y RV AVN G+ P A F+ GPP P V ++
Sbjct: 20525 ECIITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIP---EVTKIT 20581
Query: 883 DTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLF 942
++++ W P G + GY +E + W L+ T V L + +
Sbjct: 20582 KNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQY 20641
Query: 943 RVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPR 1002
RV A N AG G +E + + P G P + I K
Sbjct: 20642 RVCAVNAAGQGPFSEPSEFYKAADPIDPP----------------GPPAKIRIADSTKSS 20685
Query: 1003 PQVTWTKE----GQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVT 1046
+ W+K G + G V IR + + V + Y V+
Sbjct: 20686 ITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVS 20733
Score = 112 bits (281), Expect = 2e-24
Identities = 106/428 (24%), Positives = 172/428 (40%), Gaps = 58/428 (13%)
Query: 867 IGPPSEPTH-LAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTE 925
IG P+ P L +D+ +V + WRPP G + GY +E + W +
Sbjct: 23728 IGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYT-IDSRVR 23786
Query: 926 HTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQK 985
TS++VK L FRV A N G P+ + EPVT + L P + P + + +
Sbjct: 23787 GTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPP--EPPSNPPEVLDV 23844
Query: 986 KVGEPVNLLIPFQGKPRPQVTWTKE----GQPLAGEEVSIRNSPTDTILFIRAAR-RVHS 1040
K ++W++ G + G + + + TD ++R + ++ +
Sbjct: 23845 T-------------KSSVSLSWSRPKDDGGSRVTGYYIERKETSTDK--WVRHNKTQITT 23889
Query: 1041 GTYQVTVRIENMEDKATLVLQ-------------------VVDKPSPPQDLRVTDAWGLN 1081
Y VT + + E + ++ Q DKPS P +L + +
Sbjct: 23890 TMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKDS 23949
Query: 1082 VALEWKPPQDVGNTELWGYTVQKADKKTMEWF-TVLEHYRRTHCVVPELIIGNGYYFRVF 1140
V L+W+ P+ G E+ GY V+ W + E + + L+ Y FRVF
Sbjct: 23950 VTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYEFRVF 24009
Query: 1141 SQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAML 1200
++N G S RP T K L EAP + + + + G A L
Sbjct: 24010 AENETGLS-------------RPRRTAMSIKTK-LTSGEAPGIRKEMKDVTTKLGEAAQL 24055
Query: 1201 CCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQG 1260
C + G P P I W++ G +L + +++M S TL + D G+Y C ATN G
Sbjct: 24056 SCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVG 24115
Query: 1261 EARCECRL 1268
E +L
Sbjct: 24116 EVETSSKL 24123
Score = 112 bits (280), Expect = 2e-24
Identities = 127/527 (24%), Positives = 203/527 (38%), Gaps = 79/527 (14%)
Query: 769 IDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFD-LIQ 827
I P P PK+ + ++ + W P DGG PILGY++E +K + +W R+N D LI+
Sbjct: 11304 IKPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKDELIR 11363
Query: 828 ELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMP---IGPPSEPTHLAVEDVSDT 884
+ + +IEG Y R+ A N +G P ++ + + PP + DV
Sbjct: 11364 QCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRDVITV 11423
Query: 885 TVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSI-LVKDLPTGARLLFR 943
V R RV PE W + L + L++DLP R+ +
Sbjct: 11424 RVGQTIRILARVKGR----------PEPDITWTKEGKVLVREKRVDLIQDLP---RVELQ 11470
Query: 944 VRAHNMAGPGAPVTTTEPVT-------VQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIP 996
++ A G + + + + + +L RP G NL +
Sbjct: 11471 IKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRP----------------GPCQNLKVT 11514
Query: 997 FQGKPRPQVTWTKE----GQPLAGEEVSIRNS--------PTDTILFIRAARRVHSGTYQ 1044
K ++W G + V R +D + A + + Y
Sbjct: 11515 NVTKENCTISWENPLDNGGSEITNFIVEYRKPNQKGWSIVASDVTKRLIKANLLANNEYY 11574
Query: 1045 VTVRIEN-------MEDKAT-LVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTE 1096
V EN +E K L + +D+P P++L + D V L+W+ P G +
Sbjct: 11575 FRVCAENKVGVGPTIETKTPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSP 11634
Query: 1097 LWGYTVQKADKKTMEWFTVLE-HYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTK 1155
Y V++ K + +W V + + TH +V + Y FRV ++N G SD T +
Sbjct: 11635 NLSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVENQIYEFRVQTKNEGGESDWVKTEE 11694
Query: 1156 EPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWF 1215
+ E LD + T V AG T L VRG P P+++W
Sbjct: 11695 V--------VVKEDLQKPVLDLKLSGVLT-------VKAGDTIRLEAGVRGKPFPEVAWT 11739
Query: 1216 --KNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQG 1260
K+ DL R ++ ++ + K DGG YV ATN G
Sbjct: 11740 KDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAG 11786
Score = 110 bits (274), Expect = 1e-23
Identities = 148/625 (23%), Positives = 238/625 (38%), Gaps = 79/625 (12%)
Query: 684 QKAITQGNKAPARPAPDAPEDTGDS-DEWVFDKKLLCETEGRVRVETTKD--------RS 734
Q +T+ K A + P D G ++ +K+ ET + TKD R
Sbjct: 10520 QPIVTEVTKDSALVTWNKPHDGGKPITNYILEKR---ETMSKRWARVTKDPIHPYTKFRV 10576
Query: 735 IFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDV------PDAPAAPKISNVGEDSC 788
+EG + E + V+ +N +G + K + P P P+ + +S
Sbjct: 10577 PDLLEGCQYE----FRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSV 10632
Query: 789 TVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNF--DLIQELSHEARRMIEGVVYEMRV 846
+ W+PP +DGG ILGYI+E +K W R N + E ++ + +G Y+ RV
Sbjct: 10633 DLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRV 10692
Query: 847 YAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSV 906
AVNA G S P+ +P + + EP L ++ +K R+ A +
Sbjct: 10693 LAVNAAGESDPAHVPEPVL-VKDRLEPPELILDANMAREQHIKVGDTLRLSA------II 10745
Query: 907 EYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQE 966
+ P W + T + P G++L R AH G + +T P +
Sbjct: 10746 KGVPFPKVTW--KKEDRDAPTKARIDVTPVGSKLEIRNAAHEDGGIYS-LTVENPAGSKT 10802
Query: 967 ILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKE----GQPLAGEEVSIR 1022
+ ++ + K G P +L + K +TW + G + V R
Sbjct: 10803 V----------SVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERR 10852
Query: 1023 N------SPTDTILFIRA--ARRVHSGT-YQVTVRIENMEDKATLV--------LQVVDK 1065
+ SP ++ A+ ++ G Y V EN + V L +
Sbjct: 10853 DVASAQWSPLSATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHP 10912
Query: 1066 PSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCV 1125
P PP+DL D V+L W P G + + GY V+ ++ T +W + CV
Sbjct: 10913 PGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIK-FKTVTNLECV 10971
Query: 1126 VPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQ 1185
V L G Y FRV ++N+VG T P+ + PP+ + LD +
Sbjct: 10972 VTGLQQGKTYRFRVKAENIVGLG--LPDTTIPIECQEKLV---PPSVE-LDV----KLIE 11021
Query: 1186 PLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCP 1245
LV V AG T +RG P P W +G ++ D + + + L I+
Sbjct: 11022 GLV---VKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLR 11078
Query: 1246 FDGGIYVCRATNLQGEARCECRLEV 1270
D G Y +N G L V
Sbjct: 11079 RDTGEYQITVSNAAGSKTVAVHLTV 11103
Score = 109 bits (272), Expect = 2e-23
Identities = 185/803 (23%), Positives = 284/803 (35%), Gaps = 153/803 (19%)
Query: 542 EKKLEVYQSIADLMVGAKDQAVFK-CEVSDENVRGVWLKN--GKELVPDSRIKVSHIGRV 598
+K+L++ + ++ G + AV K C+ SD + +KN G + V + G
Sbjct: 22588 DKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLDSPGPC 22647
Query: 599 HKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIH-LDCPGRIPD 657
KLT+ VT A +L + E+ V R+E +++ + G P
Sbjct: 22648 GKLTVSRVTQEKCT--------LAWSLPQEDGGAEITHYIVERRETSRLNWVIVEGECPT 22699
Query: 658 TIVVV--------------AGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPE 703
VV A NK VP+ +P I N P PE
Sbjct: 22700 LSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEP---------IVARNSFTIPSPPGIPE 22750
Query: 704 DTGDSDEWVFDKKLLCETEGRVRVET----------------TKDRSIFT--------VE 739
+ G E + + E++G + KD ++ +E
Sbjct: 22751 EVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLME 22810
Query: 740 GAEKEDEGVYTVTVKNPVGEDQVNLTVKVID------VPDAPAAPKISNVGEDSCTVQWE 793
G + + + VT N G + + I P P+AP++ + + S ++ W
Sbjct: 22811 GCDYQ----FRVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWT 22866
Query: 794 PPAYDGGQPILGYILERKKKKSYRWMRLNFDL-IQELSHEARRMIEGVVYEMRVYAVNAI 852
P YDGG I+GY+LE ++K + +W R++ + I+ + G Y RV AVN
Sbjct: 22867 KPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVK 22926
Query: 853 GMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTT-----------VSLKWRPPERVGAGGL 901
GMS S + P+ P +D+ T VS+ RPP
Sbjct: 22927 GMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIRAGASLRLMVSVSGRPPP------- 22979
Query: 902 DGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARL-LFRVRAHNMAGPGAPVTTTE 960
+ + +G A+ TE S+L+ D + + A N +G + +
Sbjct: 22980 ---VITWSKQGIDLASRAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVK 23036
Query: 961 PVTVQEILQRPRLQLPRHLRQTIQKKV-----GEPVNLLIPFQGKPRPQVTWTKEGQPLA 1015
+++ TI ++ G PVN I + +E A
Sbjct: 23037 VYDTPGPCPSVKVKEVSRDSVTITWEIPTIDGGAPVNNYIVEK----------REAAMRA 23086
Query: 1016 GEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENM--------EDKATLVLQVVDKPS 1067
+ V+ + S T R + V Y V EN+ A LV +V P
Sbjct: 23087 FKTVTTKCSKT----LYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSEV---PL 23139
Query: 1068 PPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWF-------TVLEHYR 1120
P L V D V L W+ P G + L GY ++ T W TVLEH
Sbjct: 23140 VPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEH-- 23197
Query: 1121 RTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEA 1180
V L G Y FR+ +QN G S+ PR +T D
Sbjct: 23198 ----TVTSLNEGEQYLFRIRAQNEKGVSE-----------PRETVTA----VTVQDLRVL 23238
Query: 1181 PSF---TQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLT 1237
P+ T P V AG L + G P P SWF G L E R + + V
Sbjct: 23239 PTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAK 23298
Query: 1238 LEIRKPCPFDGGIYVCRATNLQG 1260
L IR+ D G Y N+ G
Sbjct: 23299 LTIRETTIRDTGEYTLELKNVTG 23321
Score = 108 bits (270), Expect = 3e-23
Identities = 83/275 (30%), Positives = 134/275 (48%), Gaps = 11/275 (4%)
Query: 374 QVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAA 433
++ +G K ++ V+W ++ + ++ SG KY + G KR L + +L D
Sbjct: 6065 EILEGEKAEFVCSISKESFPVQWKRDDKTLE-SGDKYDVIADGKKRVLVVKDATLQDMGT 6123
Query: 434 YQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVEL 493
Y +VG + + L V E + I PL+D V Q V F CEV+ EGA+ KW ++ E
Sbjct: 6124 YVVMVGAARAAAHLTVIEK-LRIVVPLKDTRVKEQQEVVFNCEVNTEGAKAKWFRN--EE 6180
Query: 494 TREETFKYRFKKDGQRHHLIINEAMLEDAGHY--ALCTSGGQ---ALAELIVQEKKLEVY 548
++ KY + + L I +A L+D +Y +L G+ + A LIV+E+ L +
Sbjct: 6181 AIFDSSKYIILQKDLVYTLRIRDAHLDDQANYNVSLTNHRGENVKSAANLIVEEEDLRIV 6240
Query: 549 QSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTP 608
+ + D+ K F C+V+ NV W KNG+E+ D+R+ H LTI D
Sbjct: 6241 EPLKDIETMEKKSVTFWCKVNRLNVTLKWTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGF 6300
Query: 609 ADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQE 643
DE +Y V G ++ A+L +E +FV E
Sbjct: 6301 PDEGEY-IVTAGQDKSV-AELLIIEAPTEFVEHLE 6333
Score = 107 bits (268), Expect = 6e-23
Identities = 72/235 (30%), Positives = 117/235 (49%), Gaps = 8/235 (3%)
Query: 384 TVELADHDAE-VKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEK 442
TVEL + + V+W+KNG ++ S KY G +L I C++ D++ Y +G
Sbjct: 2681 TVELTHPNVKGVQWIKNGVVLE-SNEKYAISVKGTIYSLRIKNCAIVDESVYGFRLGRLG 2739
Query: 443 CSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYR 502
S L V+ V I + +D + V FE VS + VKW VE+ + K+R
Sbjct: 2740 ASARLHVET--VKIIKKPKDVTALENATVAFEVSVSHDTVPVKWFHKSVEIKPSD--KHR 2795
Query: 503 FKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQA 562
+ + H L++ DAG Y + A+L V+ L + +++ ++ V A
Sbjct: 2796 LVSERKVHKLMLQNISPSDAGEYTAVVGQLECKAKLFVET--LHITKTMKNIEVPETKTA 2853
Query: 563 VFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFV 617
F+CEVS NV +WLKNG E+ + K+ G++H+L I + + D A+Y+FV
Sbjct: 2854 SFECEVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFV 2908
Score = 107 bits (268), Expect = 6e-23
Identities = 98/412 (23%), Positives = 161/412 (39%), Gaps = 41/412 (9%)
Query: 868 GPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHT 927
GPP+ P ++ DV+ +++ W+PP+ G + Y VE W G ++ T
Sbjct: 11108 GPPTGPINIL--DVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSK-T 11164
Query: 928 SILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKV 987
+ + L G +FRVRA N G G P+ +T V + + P + + +
Sbjct: 11165 KLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVA------KHKFSPPSPPGKPVVTDI 11218
Query: 988 GE---PVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQ 1044
E V+ +P P + E + + G+ V + +P + F R TY+
Sbjct: 11219 TENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVNKTPIADLKF-RVTGLYEGNTYE 11277
Query: 1045 VTVRIENM--------EDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTE 1096
V EN+ + + P PP + ++ D L W P G +
Sbjct: 11278 FRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGGSP 11337
Query: 1097 LWGYTVQKADKKTMEWFTVLEHYRRTHCV--VPELIIGNGYYFRVFSQNMVGFSDRAATT 1154
+ GY V+ T +W + + C VP LI GN Y FR+ + N+VG +
Sbjct: 11338 ILGYVVECQKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELA 11397
Query: 1155 KEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIA---GYTAMLCCAVRGSPKPK 1211
+ + A D P + R VI G T + V+G P+P
Sbjct: 11398 ESVI---------------AKDILHPPEVELDVTCRDVITVRVGQTIRILARVKGRPEPD 11442
Query: 1212 ISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEAR 1263
I+W K G L + R + + L+I++ D G Y+ A N G A+
Sbjct: 11443 ITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSGHAQ 11494
Score = 106 bits (265), Expect = 1e-22
Identities = 124/571 (21%), Positives = 216/571 (37%), Gaps = 99/571 (17%)
Query: 736 FTVEGAEKEDEGVYTVTVKNPVGEDQVNLT---VKVIDV---PDAPAAPKISNVGEDSCT 789
+ V G + E + + +N G + T K D P P P++ + S +
Sbjct: 15217 YKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSIS 15276
Query: 790 VQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDL-IQELSHEARRMIEGVVYEMRVYA 848
+ W P YDGG I GY++E + W + ++ S+ + E Y++R+YA
Sbjct: 15277 IAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYA 15336
Query: 849 VNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTT----------------VSLKWRP 892
+N+ G+ P+ +P P +E L E D V +K RP
Sbjct: 15337 MNSEGLGEPA-----LVPGTPKAEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRP 15391
Query: 893 PERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGP 952
V G S++ A+++ + +T ++V ++ + + N +G
Sbjct: 15392 APEVKWARDHGESLDK---------ASIESTSSYTLLIVGNVNRFDSGKYILTVENSSGS 15442
Query: 953 GAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQ 1012
+ +L P G P +L + K +TW
Sbjct: 15443 KSAFVNVR------VLDTP----------------GPPQDLKVKEVTKTSVTLTWDP--- 15477
Query: 1013 PLAGEEVSIRNSPTDTILFIRAA-RRVHSGTYQVTVRIENMEDKATLVLQVV-------- 1063
PL I+N + R A V + ++ + +++ +++ + +V+
Sbjct: 15478 PLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLAENEYGIG 15537
Query: 1064 ------------DKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTME 1111
++P PP + + D +V+L W+ P+ G + + GY V+ K + +
Sbjct: 15538 LPAETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDK 15597
Query: 1112 WFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPN 1171
W T + T + LI G Y FRV +QN G SD P + P I
Sbjct: 15598 WATCAT-VKVTEATITGLIQGEEYSFRVSAQNEKGISD-------PRQLSVPVI------ 15643
Query: 1172 YKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFS 1231
A D P+F +V+AG + G P P ++W K+ + L + R S
Sbjct: 15644 --AKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAES 15701
Query: 1232 KQGVLTLEIRKPCPFDGGIYVCRATNLQGEA 1262
+ L I+ C D G YV + TN GEA
Sbjct: 15702 TENNSLLTIKDACREDVGHYVVKLTNSAGEA 15732
Score = 105 bits (263), Expect = 2e-22
Identities = 87/330 (26%), Positives = 141/330 (42%), Gaps = 40/330 (12%)
Query: 644 PPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPE 703
PP I L R DTI V AG + + ++G P P + W K N+ DA +
Sbjct: 8897 PPTIKLRLSVR-GDTIKVKAGEPVHIPADVTGLPMPKIEWSK-----NETVIEKPTDALQ 8950
Query: 704 DTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVN 763
T + V ++ ++ ++ A +ED+G YTVT N +G N
Sbjct: 8951 ITKEE------------------VSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRN 8992
Query: 764 LTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERK--KKKSYRWMRL 821
+ V+V D P P ++++ +SC + W+ P +GG I Y+++++ +K W +
Sbjct: 8993 VHVEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEV 9052
Query: 822 NFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQ-----PFMPIGPPSEPTHL 876
+ E + ++I YE RV AVN G+S + + P+ GPP +P L
Sbjct: 9053 TNTAV-EKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVL 9111
Query: 877 AVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSIL-----V 931
A + ++ + W PP G + GY +E EG W + + V
Sbjct: 9112 A---RTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVGLKGVEFNV 9168
Query: 932 KDLPTGARLLFRVRAHNMAGPGAPVTTTEP 961
L G + FR A N AG G P ++P
Sbjct: 9169 PRLLEGVKYQFRAMAINAAGIGPPSEPSDP 9198
Score = 105 bits (263), Expect = 2e-22
Identities = 85/322 (26%), Positives = 132/322 (40%), Gaps = 40/322 (12%)
Query: 657 DTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKK 716
D +++ +G LR+ + G P P V W K G
Sbjct: 21469 DGLIIKSGESLRIKALVQGRPVPRVTWFK---DG-------------------------- 21499
Query: 717 LLCETEGRVRVETTK---DRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPD 773
E E R+ +E T S+F V A ++ GVYTV KN G + + VKV D P
Sbjct: 21500 --VEIEKRMNMEITDVLGSTSLF-VRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPG 21556
Query: 774 APAAP-KISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHE 832
P + +N+ + T+ W+ P DG PI YI+E+++ W + D + S+
Sbjct: 21557 KVVGPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIE-DKCEAQSYT 21615
Query: 833 ARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPI--GPPSEPTHLAVEDVSDTTVSLKW 890
A ++I G Y+ RV AVN G+ RP + I P P +++ +++L W
Sbjct: 21616 AIKLINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTW 21675
Query: 891 RPPERVGAGGLDGYSVEYCPEGCSEWVAAL-QGLTEHTSILVKDLPTGARLLFRVRAHNM 949
PE G + Y +E + + WV + + T V L G F V A N
Sbjct: 21676 ARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVMAENA 21735
Query: 950 AGPGAPVTTTEPVTVQEILQRP 971
AG G + + +E + P
Sbjct: 21736 AGVGPASGISRLIKCREPVNPP 21757
Score = 105 bits (261), Expect = 4e-22
Identities = 130/548 (23%), Positives = 207/548 (37%), Gaps = 57/548 (10%)
Query: 738 VEGAEKEDEGVYTVTVKNPVGEDQ---VNLTVKVIDV---PDAPAAPKISNVGEDSCTVQ 791
V G ++ E + V+ +N G + + K D P P I + ++S T+
Sbjct: 17383 VTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLA 17442
Query: 792 WEPPAYDGGQPILGYILERKKKKSYRWMRLNFDL-IQELSHEARRMIEGVVYEMRVYAVN 850
W P YDGG ILGY++E K W + ++ E ++ E Y++RV A+N
Sbjct: 17443 WGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALN 17502
Query: 851 AIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCP 910
+G+ + P P + + + R V AGG + +
Sbjct: 17503 KVGLGEATSVPGTVKPEDKLEAP---------ELDLDSELRKGIVVRAGGSARIHIPFKG 17553
Query: 911 EGCSE--WVAALQGLTE---------HTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTT 959
E W T+ +T + + + + ++ N +G + T
Sbjct: 17554 RPTPEITWSREEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVT- 17612
Query: 960 EPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEV 1019
V V + P+ + +R+ V EP +I K + V +E A V
Sbjct: 17613 --VKVLDTPGPPQNLAVKEVRKDSAFLVWEPP--IIDGGAKVKNYVIDKRESTRKAYANV 17668
Query: 1020 SIRNSPTDTILFIRAARRVHSGTYQVTVRIEN-----MEDKATLVLQVVDKPSPPQDLRV 1074
S + S T + Y V EN + + ++ + PSPP + +
Sbjct: 17669 SSKCSKTS----FKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEPPSPPGKVTL 17724
Query: 1075 TDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNG 1134
TD + +L W+ P+ G + + GY V+ K T +W V E + + VV L G
Sbjct: 17725 TDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAES-KVCNAVVTGLSSGQE 17783
Query: 1135 YYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIA 1194
Y FRV + N G SD P + P I A D + PS P S+ A
Sbjct: 17784 YQFRVKAYNEKGKSD-------PRVLGVPVI--------AKDLTIQPSLKLPFNTYSIQA 17828
Query: 1195 GYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCR 1254
G + V G P+P ISW K+G L + R + L I++ D G Y
Sbjct: 17829 GEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVT 17888
Query: 1255 ATNLQGEA 1262
ATN G A
Sbjct: 17889 ATNSAGTA 17896
Score = 104 bits (260), Expect = 5e-22
Identities = 129/579 (22%), Positives = 235/579 (40%), Gaps = 81/579 (13%)
Query: 725 VRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPKISNVG 784
+ V K++S+ K ++G+ P+ ++ +T +V D+ D P A +G
Sbjct: 21023 IEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPITVKELIITPEV-DLSDIPGAQVTVRIG 21081
Query: 785 EDSCTVQWEPPAYDGGQPILGYI---LERKKKKSYRWMRLNFDLIQELSHEARRMIEGVV 841
+ V E P +P + ++ L K+ + R+ + + + + A++ G
Sbjct: 21082 HN---VHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKN-AKKEHGGKY 21137
Query: 842 YEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTH-LAVEDVSDTTVSLKWRPPERVGAGG 900
+ AV I + P + + +GPPS+P + +++ +V L W PE G G
Sbjct: 21138 TVILDNAVCRIAV----PIT--VITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGE 21191
Query: 901 LDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTE 960
+ YS+E + W + T+ V +L A FRVRA N G ++
Sbjct: 21192 ITCYSIEKRETSQTNWKMVCSSVAR-TTFKVPNLVKDAEYQFRVRAENRYG------VSQ 21244
Query: 961 PVTVQEILQRPRLQLPRHL-RQTIQKKVGEPVNLL--------------IPFQGKPRPQV 1005
P+ I+ + + ++P + I + ++L + K R +
Sbjct: 21245 PLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSI 21304
Query: 1006 TWTKEG-QPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENME--------DKA 1056
W K P++G E RA V YQ V EN K
Sbjct: 21305 LWQKVNTSPISGREY-------------RATGLVEGLDYQFRVYAENSAGLSSPSDPSKF 21351
Query: 1057 TLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEW---- 1112
TL + VD P P + VT + L+W PP G +++ GY+++K W
Sbjct: 21352 TLAVSPVDPPGTPDYIDVTRE---TITLKWNPPLRDGGSKIVGYSIEKRQGNE-RWVRCN 21407
Query: 1113 FTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNY 1172
FT + + T V L G+ Y FR+ ++N VG + + + + PP
Sbjct: 21408 FTDVSECQYT---VTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENV---PP-- 21459
Query: 1173 KALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSK 1232
++F P + L+ +S G + + V+G P P+++WFK+G+++ + +
Sbjct: 21460 -IVEFG--PEYFDGLIIKS---GESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDV 21513
Query: 1233 QGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVR 1271
G +L +R G+Y A N G A+ E +++V+
Sbjct: 21514 LGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQ 21552
Score = 103 bits (257), Expect = 1e-21
Identities = 124/529 (23%), Positives = 187/529 (35%), Gaps = 95/529 (17%)
Query: 772 PDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDL-IQELS 830
P PA PK+ + S ++ W PAYDGG PI+GY++E K+ S W+R N +Q+
Sbjct: 13092 PGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTR 13151
Query: 831 HEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTT----- 885
E ++E Y+ RVYAVN IG S PS P P D+ T
Sbjct: 13152 FEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAG 13211
Query: 886 ------VSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGAR 939
V +K RPP ++ W L + + +K T
Sbjct: 13212 VTMRLYVPVKGRPPPKI------------------TWSKPNVNLRDRIGLDIKS--TDFD 13251
Query: 940 LLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKV----GEPVNLLI 995
R N G + T E ++ TI KV G PVN+ +
Sbjct: 13252 TFLRCENVNKYDAGKYILTLENSCGKK-------------EYTIVVKVLDTPGPPVNVTV 13298
Query: 996 PFQGKPRPQVTWTKE----GQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIEN 1051
K VTW G P+ V R++ ++ V + + + R+ N
Sbjct: 13299 KEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAER------KSWSTVTTECSKTSFRVAN 13352
Query: 1052 MEDKATLVLQVVDK--------------------PSPPQDLRVTDAWGLNVALEWKPPQD 1091
+E+ + +V + P P DL+V + ++ WK P
Sbjct: 13353 LEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVVDLKVRSVSKSSCSIGWKKPHS 13412
Query: 1092 VGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRA 1151
G + + GY V ++ +W V++ + +L G Y FRV ++N G
Sbjct: 13413 DGGSRIIGYVVDFLTEEN-KWQRVMKSLSLQYSA-KDLTEGKEYTFRVSAENENG----E 13466
Query: 1152 ATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPK 1211
T E + R + LD P S L ++G P P
Sbjct: 13467 GTPSEITVVARDDVVAPD-----LDLKGLPDLCYLAKENS-----NFRLKIPIKGKPAPS 13516
Query: 1212 ISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQG 1260
+SW K L D R + S TL + D G Y N+ G
Sbjct: 13517 VSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAG 13565
Score = 102 bits (255), Expect = 2e-21
Identities = 114/505 (22%), Positives = 205/505 (40%), Gaps = 45/505 (8%)
Query: 704 DTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVN 763
D G E + L T+ VRV + + G + E + V N GE + +
Sbjct: 7513 DGGAKIESYVIEMLKTGTDEWVRVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPS 7572
Query: 764 ------LTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYR 817
L + + P P ++ N+ +++ ++W P DGG PI YI+E++ +
Sbjct: 7573 EPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKG 7632
Query: 818 WMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMP---IGPPSEPT 874
W ++ +++ + EG +Y RV A NAIG S + + P P
Sbjct: 7633 WQTVD-TTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPY 7691
Query: 875 HLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDL 934
LAV DV+ V LKW PP+ G + Y +E + WV A + + V D+
Sbjct: 7692 ALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDV 7751
Query: 935 PTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLL 994
G + F+VRA N AG G P TE +++++ P L H+ +K + +
Sbjct: 7752 IEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIA--IAWK 7809
Query: 995 IPFQGKPRPQVTWTKEGQPLAGEE-VSIRNSPTDTILFIRAARRVHSGTYQVTVRIEN-- 1051
P + P + + E P+ E+ + + + P + F V Y + VR N
Sbjct: 7810 PPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAI 7869
Query: 1052 -MEDKATLVLQVVDKPS--------PPQDLRVTDAWGLNVALEWKP-PQDVGNTELWGYT 1101
+ + + + VV K D+ V + L++ + ++ P + G
Sbjct: 7870 GVSEPSEISENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKE 7929
Query: 1102 VQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIP 1161
V+ +D+ TM+ + H VP+ + + + + +N +G S A+ + + +P
Sbjct: 7930 VKASDRLTMK-----NDHISAHLEVPKSVRADAGIYTITLENKLG-SATASINVKVIGLP 7983
Query: 1162 RP--------------GITYEPPNY 1172
P +T+EPP +
Sbjct: 7984 GPCKDIKASDITKSSCKLTWEPPEF 8008
Score = 102 bits (255), Expect = 2e-21
Identities = 86/332 (25%), Positives = 131/332 (39%), Gaps = 39/332 (11%)
Query: 644 PPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPE 703
PP +HLD D + + G L SG P P V W K
Sbjct: 10320 PPTLHLD----FRDKLTIRVGEAFALTGRYSGKPKPKVSWFK------------------ 10357
Query: 704 DTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVN 763
D D E + R ++TT A++ D G Y V V+N G +
Sbjct: 10358 DEADVLE-----------DDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGF 10406
Query: 764 LTVKVIDVPDAPAAP-KISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLN 822
V V+D P P P V +D + W+PP DGG I YI+E+K+ WM +
Sbjct: 10407 CQVNVVDRPGPPVGPVSFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPVT 10466
Query: 823 FDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRP--SPASQPFMPIGPPSEPTHLAVED 880
+ + + +++EG Y R++A N G+S P S + + P P V +
Sbjct: 10467 -SASAKTTCKVSKLLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTE 10525
Query: 881 VSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQG-LTEHTSILVKDLPTGAR 939
V+ + + W P G + Y +E W + + +T V DL G +
Sbjct: 10526 VTKDSALVTWNKPHD-GGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQ 10584
Query: 940 LLFRVRAHNMAGPGAPVTTTEPVTVQEILQRP 971
FRV A N G G P ++PV ++ + +P
Sbjct: 10585 YEFRVSAENEIGIGDPSPPSKPVFAKDPIAKP 10616
Score = 102 bits (253), Expect = 3e-21
Identities = 150/635 (23%), Positives = 235/635 (37%), Gaps = 110/635 (17%)
Query: 680 TVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVE 739
TV+W +RP D D DKK L +V ET +D V
Sbjct: 20586 TVVW-----------SRPIADGGSDISGYFLEKRDKKSLGWF--KVLKETIRDTRQ-KVT 20631
Query: 740 GAEKEDEGVYTVTVKNPVGE------DQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWE 793
G + + Y V N G+ + ID P PA +I++ + S T+ W
Sbjct: 20632 GLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSITLGWS 20691
Query: 794 PPAYDGGQPILGYILERKKKKSYRWMRLNFD-LIQELSHEARRMIEGVVYEMRVYAVNAI 852
P YDGG + GY++E ++ + W ++ ++ + + GV Y RV AVN
Sbjct: 20692 KPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCA 20751
Query: 853 GMSRPSPASQPFMP---IGPPSEPTHLAV---------EDVSDTTVSLKWRPPERV---- 896
G P ++P + P +A+ EDV + K RPP V
Sbjct: 20752 GQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAGEDVQ-VLIPFKGRPPPTVTWRK 20810
Query: 897 ---GAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSIL----VKDLPTGARLLFRVRAHNM 949
G YS+E T+ +S+L V TG +L
Sbjct: 20811 DEKNLGSDARYSIEN---------------TDSSSLLTIPQVTRNDTGKYILTIEN---- 20851
Query: 950 AGPGAPVTTTEPVTVQEILQRP----RLQLPRHLRQTIQKKVGEP--------VNLLIPF 997
G G P ++T V ++L P +LQ+ R T+ P +N +I
Sbjct: 20852 -GVGEPKSSTVSV---KVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVI-- 20905
Query: 998 QGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKAT 1057
+ + + TW+ + + + T F R G + + T
Sbjct: 20906 EKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPC--------ETT 20957
Query: 1058 LVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLE 1117
++ + P+P +DL + D+ +V L W P G + + Y V++ K W +
Sbjct: 20958 EPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERKGKGEQTW-SHAG 21016
Query: 1118 HYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDF 1177
+ V +L + FRVF++N G SD T P+ + IT E +D
Sbjct: 21017 ISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSD--PVTIGPITVKELIITPE------VDL 21068
Query: 1178 SEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLT 1237
S+ P +V G+ L +G PKP ISW K+GL L E R + +T
Sbjct: 21069 SDIPG-----AQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKIT 21123
Query: 1238 LEIRKPCPFDGGIYVCRATNLQGEARCECRLEVRV 1272
L I+ GG Y N CR+ V +
Sbjct: 21124 LSIKNAKKEHGGKYTVILDN------AVCRIAVPI 21152
Score = 101 bits (252), Expect = 4e-21
Identities = 134/560 (23%), Positives = 208/560 (37%), Gaps = 74/560 (13%)
Query: 736 FTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPP 795
+TV+G ++ D Y V+ N VG+ + + K I D A P + D T++
Sbjct: 10279 YTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHLDFRDKLTIRV--- 10335
Query: 796 AYDGGQPILGYILERKKKKSYRWMRLNFDLIQE-LSH-------------EARRMIEG-- 839
G L K K W + D++++ +H +A+R G
Sbjct: 10336 ---GEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKY 10392
Query: 840 -VVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGA 898
VV E + G + + +P P+GP S ++V+ + + W+PP G
Sbjct: 10393 CVVVENSTGSRK--GFCQVNVVDRPGPPVGPVS------FDEVTKDYMVISWKPPLDDGG 10444
Query: 899 GGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTT 958
+ Y +E G W+ + T+ V L G +FR+ A N+ G
Sbjct: 10445 SKITNYIIEKKEVGKDVWMPVTSASAK-TTCKVSKLLEGKDYIFRIHAENLYG------I 10497
Query: 959 TEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLI---PFQG-KPRPQVTWTKEGQPL 1014
++P+ + + R ++P Q I +V + L+ P G KP K + +
Sbjct: 10498 SDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHDGGKPITNYILEKR-ETM 10556
Query: 1015 AGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENM--------EDKATLVLQVVDKP 1066
+ + P R + Y+ V EN K + KP
Sbjct: 10557 SKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKP 10616
Query: 1067 SPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVL---EHYRRTH 1123
SPP + D +V L W+PP+ G +++ GY V+ EW E T
Sbjct: 10617 SPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPETK 10676
Query: 1124 CVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGIT---YEPPNYKALDFSEA 1180
V L G Y FRV + N G SD P +P P + EPP LD + A
Sbjct: 10677 YKVTGLRDGQTYKFRVLAVNAAGESD-------PAHVPEPVLVKDRLEPPEL-ILDANMA 10728
Query: 1181 PSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEI 1240
+ + G T L ++G P PK++W K D AR + LEI
Sbjct: 10729 RE-------QHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGS--KLEI 10779
Query: 1241 RKPCPFDGGIYVCRATNLQG 1260
R DGGIY N G
Sbjct: 10780 RNAAHEDGGIYSLTVENPAG 10799
Score = 101 bits (251), Expect = 5e-21
Identities = 79/286 (27%), Positives = 133/286 (46%), Gaps = 11/286 (3%)
Query: 359 EKKSTAFQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAK 418
E+ F K LE V KG + L+ EL + + +V W K+G+ + + + IG
Sbjct: 4711 EELPVRFVKTLEEEVTVVKGQPLYLSCEL-NKERDVVWRKDGKIVVEKPGRIVPGVIGLM 4769
Query: 419 RTLTISQCSLADDAAYQCVVGGE---KCSTELFVKEPPVL---ITRPLEDQLVMVGQRVE 472
R LTI+ D Y V +CS+ VK V+ + +P+ DQ V
Sbjct: 4770 RALTINDADDTDAGTYTVTVENANNLECSS--CVKVVEVIRDWLVKPIRDQHVKPKGTAI 4827
Query: 473 FECEVSEEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGG 532
F C+++++ +KW K E+ E K +DG +L I AM ED YA+ G
Sbjct: 4828 FACDIAKDTPNIKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEGK 4887
Query: 533 QALAELIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKV 592
+ A+L + E+++E+ + I D+ + K+ A F E+S+ ++ G W G+ L P ++
Sbjct: 4888 RYPAKLTLGEREVELLKPIEDVTIYEKESASFDAEISEADIPGQWKLKGELLRPSPTCEI 4947
Query: 593 SHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDF 638
G LT+ V D+A + + +A L E+++DF
Sbjct: 4948 KAEGGKRFLTLHKV-KLDQAG-EVLYQALNAITTAILTVKEIELDF 4991
Score = 101 bits (251), Expect = 5e-21
Identities = 142/653 (21%), Positives = 242/653 (37%), Gaps = 78/653 (11%)
Query: 661 VVAGNKLRLDVPISGDP-----------APTVIWQKAITQGNKAPARPAPDAPEDTGDSD 709
++A NK + P+ +P AP ++T+ + P+ + +
Sbjct: 9794 IMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTG 9853
Query: 710 EWVFDKKLLCETEGRVRVETTKDRSI---FTVEGAEKEDEGVYTVTVKNPVGEDQVNL-- 764
W+ K + RV + K ++ + V G + + + V N G +L
Sbjct: 9854 YWLEMKDTTSKRWKRVNRDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPS 9913
Query: 765 ---TVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRL 821
T + P P PK+++ + S ++W PP DGG + GYI+E K++ W +
Sbjct: 9914 DPATARDPIAPPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKG 9973
Query: 822 NFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDV 881
++ + EG Y+ RV AVN G+ P + P V
Sbjct: 9974 KDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASV 10033
Query: 882 SDTTVSLKWRPPERVGAGGLDGYS--VEYCPEGCSEW---------VAALQGLTEHTSIL 930
D V V AGG+ V P W A ++ +S++
Sbjct: 10034 RDRIV---------VHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMV 10084
Query: 931 VKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKV--- 987
+K+ + ++ + A N AG + + V + P L +L K
Sbjct: 10085 IKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLA--HNLTNESCKLTWFS 10142
Query: 988 -----GEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGT 1042
G P+ + + + + WT + + +++ F R A G
Sbjct: 10143 PEDDGGSPITNYV-IEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGM 10201
Query: 1043 YQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTV 1102
+E E A ++ + + P P+DL V + V L W PP+ G +E+ Y +
Sbjct: 10202 GPF---VETSE--ALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVL 10256
Query: 1103 QKADKKTMEWFTVL-EHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIP 1161
+ T ++ V ++ V L G+ Y +RV + N+VG +P F
Sbjct: 10257 ESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQG-------KPSFCT 10309
Query: 1162 RPGITYE----PPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKN 1217
+P IT + PP LDF + ++ G L G PKPK+SWFK+
Sbjct: 10310 KP-ITCKDELAPPTLH-LDFRD---------KLTIRVGEAFALTGRYSGKPKPKVSWFKD 10358
Query: 1218 GLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
D+ ED R + + L LE K D G Y N G + C++ V
Sbjct: 10359 EADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNV 10411
Score = 100 bits (250), Expect = 7e-21
Identities = 118/495 (23%), Positives = 197/495 (39%), Gaps = 46/495 (9%)
Query: 736 FTVEGAEKEDEGVYTVTVKNPVG---EDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQW 792
F G E+ E + V+ +N VG +V+ D D P P+ V +S T+QW
Sbjct: 15903 FKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAIIVTRNSVTLQW 15962
Query: 793 EPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAI 852
+ P YDGG I GYI+E+K+ RWM+ +F I + E ++E YE RV A NA
Sbjct: 15963 KKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVIARNAA 16022
Query: 853 GMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEG 912
G+ S + +P ++++ T+ + +V A D Y P
Sbjct: 16023 GVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDA---DIYGK---PIP 16076
Query: 913 CSEWVAALQGLTEHTSILVKDLPTGARL----LFRVRAHNMAGPGAPVTTTEPVTVQ-EI 967
+W+ Q L+ + +K L RV + N V VTV ++
Sbjct: 16077 TIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKV 16136
Query: 968 LQRPRLQLPRHLRQTIQKKVGEPVNLL--IPFQGKPRPQVTWTKEGQPLAGEEVSIRNSP 1025
L RP P I E L P Q + + E + + ++ ++
Sbjct: 16137 LDRPG---PPEGPVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVDAN 16193
Query: 1026 TDTILFIRAARRVHSGTYQVTVRIEN-------MEDKATLVLQVVDKPSPPQDLRVTDAW 1078
T L + + + Y + N +E + + P P+ VT
Sbjct: 16194 VQT-LSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVT 16252
Query: 1079 GLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYR---RTHCVVPELIIGNGY 1135
++ + W+ P G +E+ GY ++K DK+ + W H R V LI + Y
Sbjct: 16253 KDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRC--HKRLIGELRLRVTGLIENHDY 16310
Query: 1136 YFRVFSQNMVGFSDRAATTK-----EPVFIPRPGITYEPPNYKALDFSEAP---SFTQPL 1187
FRV ++N G S+ + + +P++ P P P N K +D + + S+++P+
Sbjct: 16311 EFRVSAENAAGLSEPSPPSAYQKACDPIYKPGP-----PNNPKVIDITRSSVFLSWSKPI 16365
Query: 1188 VNRSV-IAGYTAMLC 1201
+ I GY C
Sbjct: 16366 YDGGCEIQGYIVEKC 16380
Score = 100 bits (248), Expect = 1e-20
Identities = 107/487 (21%), Positives = 186/487 (38%), Gaps = 42/487 (8%)
Query: 800 GQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSP 859
G+P+ L R MR N ++ E + + E V + Y + A S +
Sbjct: 20005 GKPLPKVTLSRDGVPLKATMRFNTEITAE--NLTINLKESVTADAGRYEITAANSSGTTK 20062
Query: 860 ASQPFMPIGPPSEPTH-LAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVA 918
A + + P PT + + D+++ +V+LKW PP+ G + Y + + W
Sbjct: 20063 AFINIVVLDRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTE 20122
Query: 919 ALQGLTEHTSILVKDLPTGARLLFRVRAHNMAG-----PGAPVTTTEPVTVQEILQRPRL 973
+ T + V L TG FR++A N G A VT P T P
Sbjct: 20123 -VSATVARTMMKVMKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTP-- 20179
Query: 974 QLPRHLRQTIQKKVGEPVN------LLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTD 1027
+ R++I EPV+ + + K R + W K ++ IR +
Sbjct: 20180 WVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQK------ANKLVIRTTHFK 20233
Query: 1028 TILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWK 1087
+ I A Y + + +D PP+++R+TD +V+L W+
Sbjct: 20234 -VTTISAGLIYEFRVYAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQ 20292
Query: 1088 PPQDVGNTELWGYTVQKADKKTMEWFTV-LEHYRRTHCVVPELIIGNGYYFRVFSQNMVG 1146
P G +++ GY V++ D W + T ++ L + Y FRVF++N VG
Sbjct: 20293 QPAFDGGSKITGYIVERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVG 20352
Query: 1147 FSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVI---AGYTAMLCCA 1203
+ P+ +D P PL V+ AG + L
Sbjct: 20353 SISNPSEVVGPI--------------TCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAG 20398
Query: 1204 VRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEAR 1263
+ G P P I W+K+ +L +A + + + ++ I+ + G Y + N G A
Sbjct: 20399 ISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRNAMGSAS 20458
Query: 1264 CECRLEV 1270
R+++
Sbjct: 20459 ATIRVQI 20465
Score = 99.4 bits (246), Expect = 2e-20
Identities = 77/249 (30%), Positives = 111/249 (44%), Gaps = 13/249 (5%)
Query: 391 DAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCV---VGGEKCSTEL 447
D E +W KNG +I+ S Y + L I + D A+ + GE S
Sbjct: 2060 DPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAF 2119
Query: 448 FVKEPPVLITRPLEDQLVMVGQR---VEFECEVSEEGAQVKWLKDGVELTREETFKYRFK 504
+ + LIT E Q V+ ++ FECE SE +VKW KDG+E+ E KYR
Sbjct: 2120 LLVQAKQLITFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEV--HEGDKYRMH 2177
Query: 505 KDGQRHHLIINEAMLEDAGHYALC---TSGGQALAELIVQEKKLEVYQSIADLMVGAKDQ 561
D + H L I DA Y+ + A+LIV+ +E + + D+ V
Sbjct: 2178 SDRKVHFLSILTIDTSDAEDYSCVLVEDENVKTTAKLIVEGAVVEFVKELQDIEVPESYS 2237
Query: 562 AVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEG- 620
+C VS EN+ G W N EL + + ++ LT+ DVT D+ +YSFV +G
Sbjct: 2238 GELECIVSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGK 2297
Query: 621 -FACNLSAK 628
C L K
Sbjct: 2298 KTTCKLKMK 2306
Score = 99.0 bits (245), Expect = 3e-20
Identities = 116/522 (22%), Positives = 200/522 (38%), Gaps = 83/522 (15%)
Query: 772 PDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDL-IQELS 830
P P+ PK+++ S ++ W P YDGG P+ GY++E K+ + W +Q
Sbjct: 18506 PGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQ 18565
Query: 831 HEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMP---IGPP-----SEPTHLAVEDVS 882
++ E Y R+ A+N+ G+ P+ + I PP ++ + V S
Sbjct: 18566 FTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRAS 18625
Query: 883 DTT---VSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGAR 939
T V++K RP V +G + A ++ + T +++ ++
Sbjct: 18626 ATLRLFVTIKGRPEPEVKWEKAEGILTDR---------AQIEVTSSFTMLVIDNVTRFDS 18676
Query: 940 LLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQG 999
+ + N +G + T V V+ +L P PVNL I
Sbjct: 18677 GRYNLTLENNSG-----SKTAFVNVR-VLDSP----------------SAPVNLTIREVK 18714
Query: 1000 KPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAA-RRVHSGTYQVTVRIENMED---- 1054
K ++W PL I N + R A + + + T RIEN+++
Sbjct: 18715 KDSVTLSWEP---PLIDGGAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSY 18771
Query: 1055 ----------------KATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELW 1098
+ T ++V + P PP + + D ++W+ P+ G +++
Sbjct: 18772 YFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKIT 18831
Query: 1099 GYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPV 1158
GY V+ K + +W T + + + L G Y FRV + N G SD P
Sbjct: 18832 GYVVEMQTKGSEKWSTCTQ-VKTLEATISGLTAGEEYVFRVAAVNEKGRSD-------PR 18883
Query: 1159 FIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNG 1218
+ P I A D PS P +V A + +G P+ ++W K+G
Sbjct: 18884 QLGVPVI--------ARDIEIKPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDG 18935
Query: 1219 LDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQG 1260
L E R + S + V +L I++ D G Y +N G
Sbjct: 18936 QTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAG 18977
Score = 99.0 bits (245), Expect = 3e-20
Identities = 115/467 (24%), Positives = 176/467 (37%), Gaps = 65/467 (13%)
Query: 824 DLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSD 883
DL L +A R+ G YE+++ NA+G + + Q GPP P + + V+
Sbjct: 20429 DLASILIKDADRLNSGC-YELKLR--NAMGSASATIRVQILDKPGPPGGP--IEFKTVTA 20483
Query: 884 TTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFR 943
++L WRPP G + Y VE W + L E I + G +FR
Sbjct: 20484 EKITLLWRPPADDGGAKITHYIVEKRETSRVVWSMVSEHL-EECIITTTKIIKGNEYIFR 20542
Query: 944 VRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRP 1003
VRA N G G P+ + V + +P + T K
Sbjct: 20543 VRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKIT-----------------KNSM 20585
Query: 1004 QVTWTKE----GQPLAGEEVSIRNSPT--------DTILFIR--AARRVHSGTYQVTVRI 1049
V W++ G ++G + R+ + +TI R + YQ V
Sbjct: 20586 TVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCA 20645
Query: 1050 ENMEDKATL--------VLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYT 1101
N + +D P PP +R+ D+ ++ L W P G + + GY
Sbjct: 20646 VNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYV 20705
Query: 1102 VQKADKKTMEWFTVLE--HYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVF 1159
V+ + EW TV R T VV L G YYFRV + N G EP+
Sbjct: 20706 VEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQG-------EPIE 20758
Query: 1160 IPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVI---AGYTAMLCCAVRGSPKPKISWFK 1216
+ P +A D EAP + R+ + AG + +G P P ++W K
Sbjct: 20759 MNEP--------VQAKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRK 20810
Query: 1217 NGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEAR 1263
+ +LG DAR+ + + L I + D G Y+ N GE +
Sbjct: 20811 DEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPK 20857
Score = 98.6 bits (244), Expect = 3e-20
Identities = 116/522 (22%), Positives = 197/522 (37%), Gaps = 81/522 (15%)
Query: 772 PDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDL-IQELS 830
P P PK+ ++ S + W P YDGG I GYI+E+ W I + +
Sbjct: 16341 PGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTN 16400
Query: 831 HEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PIGPPSEPTHLAVEDVSDTT-- 885
E +++E Y R+ A+N G+ + P + + P L + + +
Sbjct: 16401 IEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAG 16460
Query: 886 ------VSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGAR 939
V +K RP V G +DG + A + + TS+++ ++
Sbjct: 16461 GSLRLFVPIKGRPTPEVKWGKVDGEIRD---------AAIIDVTSSFTSLVLDNVNRYDS 16511
Query: 940 LLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQG 999
+ + N +G T + VTV+ +L P PVNL +
Sbjct: 16512 GKYTLTLENSSG-----TKSAFVTVR-VLDTP----------------SPPVNLKVTEIT 16549
Query: 1000 KPRPQVTWTKE----GQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVT--------- 1046
K +TW G + V R + + + H ++++
Sbjct: 16550 KDSVSITWEPPLLDGGSKIKNYIVEKREATRKS--YAAVVTNCHKNSWKIDQLQEGCSYY 16607
Query: 1047 --VRIEN-----MEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWG 1099
V EN + + ++V + P PP + V D +V+L W P+ G +++
Sbjct: 16608 FRVTAENEYGIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQ 16667
Query: 1100 YTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVF 1159
Y V+ K + +W + + V+ L G Y FRV + N G SD + V
Sbjct: 16668 YIVEMQAKHSEKW-SECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLA---VP 16723
Query: 1160 IPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGL 1219
I + EP P+F+ + SV G + + G PKP I+W K+GL
Sbjct: 16724 IVAKDLVIEP--------DVKPAFS----SYSVQVGQDLKIEVPISGRPKPTITWTKDGL 16771
Query: 1220 DLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGE 1261
L + R + + TL I++ DGG Y N+ G+
Sbjct: 16772 PLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQ 16813
Score = 98.6 bits (244), Expect = 3e-20
Identities = 125/521 (23%), Positives = 208/521 (39%), Gaps = 94/521 (18%)
Query: 736 FTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVI---DVPDAPAAPKISNVGEDSCTVQW 792
F + E+ E + V +N VG + + + D D P P+ V + T+QW
Sbjct: 16985 FKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPPGTPEPIMVKRNEITLQW 17044
Query: 793 EPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAI 852
P YDGG I GYI+E++ RWM+ +F + E + E YE RV A NA
Sbjct: 17045 TKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAA 17104
Query: 853 G-MSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSL--KWRPPERVGAGGLDGYSVEYC 909
G +S+PS ++ P A ++V +S+ K+R V AG + + +E
Sbjct: 17105 GAISKPSDSTGPI-----------TAKDEVELPRISMDPKFRDTIVVNAG--ETFRLEAD 17151
Query: 910 PEG----CSEWVAALQGLTEHTSILVKDLPTGARLLFR-----------VRAHNMAGPGA 954
G EW+ + + E +K+ A L+ + +RA N+AG
Sbjct: 17152 VHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAG--- 17208
Query: 955 PVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVN-LLIPFQGKPRPQVTWTKEGQP 1013
+ + PV V ++L RP G P + + + +TW+ Q
Sbjct: 17209 --SKSFPVNV-KVLDRP----------------GPPEGPVQVTGVTSEKCSLTWSPPLQD 17249
Query: 1014 LAGEEVS---IRNSPTDTILFIRAARRVHSGTYQVTVRIEN------------------M 1052
G ++S + T + + A V + + +VT +E +
Sbjct: 17250 -GGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPL 17308
Query: 1053 EDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEW 1112
E L+ P PP+ L VT+ ++ + W P G +E+ GY V+K D+ + W
Sbjct: 17309 ESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRW 17368
Query: 1113 FTV-LEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTK-----EPVFIPRPGIT 1166
V L + Y FRV ++N G + + T +PVF P P
Sbjct: 17369 IKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGP--- 17425
Query: 1167 YEPPNYKALDFSE---APSFTQPLVN-RSVIAGYTAMLCCA 1203
P N +D ++ ++ +P+ + S I GY +C A
Sbjct: 17426 --PTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEICKA 17464
Score = 97.4 bits (241), Expect = 8e-20
Identities = 105/411 (25%), Positives = 162/411 (39%), Gaps = 57/411 (13%)
Query: 876 LAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLP 935
L V V+ +L W P+ G + Y VE WV ++G S +V L
Sbjct: 22650 LTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLNWVI-VEGECPTLSYVVTRLI 22708
Query: 936 TGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLI 995
+FRVRA N GPG PV + EP+ + P I ++VG
Sbjct: 22709 KNNEYIFRVRAVNKYGPGVPVES-EPIVARNSFTIPS-------PPGIPEEVGT------ 22754
Query: 996 PFQGKPRPQVTWTKE----GQPLAGEEVSIRNSPT--------DTILF---IRAARRVHS 1040
GK + WTK G ++ V R + D +++ ++ +
Sbjct: 22755 ---GKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEG 22811
Query: 1041 GTYQVTVRIENME-----DKATLVLQVVDK---PSPPQDLRVTDAWGLNVALEWKPPQDV 1092
YQ V N +A+ + + P PP RV D +++L W P
Sbjct: 22812 CDYQFRVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYD 22871
Query: 1093 GNTELWGYTVQKADKKTMEWFTVLEH--YRRTHCVVPELIIGNGYYFRVFSQNMVGFSDR 1150
G T++ GY ++ +K T +W+ V + R T VP+L +G Y FRV + N+ G S+
Sbjct: 22872 GGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEY 22931
Query: 1151 AATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKP 1210
+ + E + R I D A + + R AG + L +V G P P
Sbjct: 22932 SESIAEIEPVERIEIP---------DLELADDLKKTVTIR---AGASLRLMVSVSGRPPP 22979
Query: 1211 KISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGE 1261
I+W K G+DL A +L ++ K +D G Y A N G+
Sbjct: 22980 VITWSKQGIDLASRAIIDTTESYSLLIVD--KVNRYDAGKYTIEAENQSGK 23028
Score = 95.1 bits (235), Expect = 4e-19
Identities = 68/224 (30%), Positives = 97/224 (43%), Gaps = 4/224 (1%)
Query: 391 DAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCSTELFVK 450
+A V W K G +I S K+ + G K L I+ D+ Y V G+K S LFV
Sbjct: 5015 EANVIWSK-GPDIIKSSDKFDIIADGKKHILVINDSQFDDEGVYTAEVEGKKTSARLFVT 5073
Query: 451 EPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKKDGQRH 510
+ PLEDQ V G+ F CE+S E V W K+ +L T +G+ H
Sbjct: 5074 GIRLKFMSPLEDQTVKEGETATFVCELSHEKMHVVWFKNDAKLHTSRTVL--ISSEGKTH 5131
Query: 511 HLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSD 570
L + E L+D + A+L V E + D KD+ KCEVS
Sbjct: 5132 KLEMKEVTLDDISQIKAQVKELSSTAQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVS- 5190
Query: 571 ENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADY 614
++V W K+G+E+VP + + G L I D+ +Y
Sbjct: 5191 KDVPVKWFKDGEEIVPSPKYSIKADGLRRILKIKKADLKDKGEY 5234
Score = 94.4 bits (233), Expect = 6e-19
Identities = 97/413 (23%), Positives = 161/413 (38%), Gaps = 53/413 (12%)
Query: 870 PSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSI 929
P P + +++VS ++++ W PPE G + Y VE + W Q + TSI
Sbjct: 18991 PGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQAVAR-TSI 19049
Query: 930 LVKDLPTGARLLFRVRAHNMAGPGA-----------PVTTTEPVTVQEILQRPRLQLPRH 978
+ L TG+ FRV A N G + P + P +++ + +
Sbjct: 19050 KIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTM--- 19106
Query: 979 LRQTIQKKVGEPVNLLIPF--QGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAAR 1036
T Q V + + +I + + K R + W+K + L + ++ S D L
Sbjct: 19107 -LVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANKILIAD-TQMKVSGLDEGLM----- 19159
Query: 1037 RVHSGTYQVTVRIENME-----DKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQD 1091
Y+ V EN+ K+ + D PP VT+ +V+L+W P
Sbjct: 19160 ------YEYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQPEVTNITRKSVSLKWSKPHY 19213
Query: 1092 VGNTELWGYTVQKADKKTMEWFTV-LEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDR 1150
G ++ GY V++ + W + + T+ V EL Y FRVF++N
Sbjct: 19214 DGGAKITGYIVERRELPDGRWLKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSE 19273
Query: 1151 AATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVI---AGYTAMLCCAVRGS 1207
+ + P+ + D E P + R VI AG + + G
Sbjct: 19274 PSESTGPIIVK--------------DDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGR 19319
Query: 1208 PKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQG 1260
P P ISW K+G+++ E AR + S L ++ D G YV N+ G
Sbjct: 19320 PLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAG 19372
Score = 93.2 bits (230), Expect = 1e-18
Identities = 98/428 (22%), Positives = 164/428 (38%), Gaps = 61/428 (14%)
Query: 868 GPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHT 927
GPP+ P + ++V+ +++L W PP+ G ++ Y VE + W + T
Sbjct: 15745 GPPTGPVKM--DEVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTW-QIVSATVART 15801
Query: 928 SILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQ----LPRHLRQTI 983
+I L TG FR+ A N G + + EP Q + P + R ++
Sbjct: 15802 TIKACRLKTGCEYQFRIAAENRYGKSTYLNS-EPTVAQYPFKVPGPPGTPVVTLSSRDSM 15860
Query: 984 QKKVGEPVN------LLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARR 1037
+ + EP++ + + K R + W K + +P F +
Sbjct: 15861 EVQWNEPISDGGSRVIGYHLERKERNSILWVK-----------LNKTPIPQTKF-KTTGL 15908
Query: 1038 VHSGTYQVTVRIENME--------DKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPP 1089
Y+ V EN+ + + D P P+ + VT +V L+WK P
Sbjct: 15909 EEGVEYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAIIVTRN---SVTLQWKKP 15965
Query: 1090 QDVGNTELWGYTVQKADKKTMEWFTV-LEHYRRTHCVVPELIIGNGYYFRVFSQNMVGF- 1147
G +++ GY V+K + W + TH V L+ + Y FRV ++N G
Sbjct: 15966 TYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVF 16025
Query: 1148 -----SDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCC 1202
S A T ++ V PR S P + +V V AG + +
Sbjct: 16026 SEPSESTGAITARDEVDPPR--------------ISMDPKYKDTIV---VHAGESFKVDA 16068
Query: 1203 AVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEA 1262
+ G P P I W K +L AR + S +L ++ D G Y+ +A N+ GE
Sbjct: 16069 DIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGER 16128
Query: 1263 RCECRLEV 1270
++V
Sbjct: 16129 SVTVNVKV 16136
Score = 92.4 bits (228), Expect = 2e-18
Identities = 114/418 (27%), Positives = 156/418 (37%), Gaps = 43/418 (10%)
Query: 870 PSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGC--SEWVAALQGLTEHT 927
P P + ED+ T+V KW PP G + Y++E + SEW+ L H
Sbjct: 8305 PGPPINFVFEDIRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWIVVTSTL-RHC 8363
Query: 928 SILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKV 987
V L G LFRVRA N GPG P + +P+ ++ P K +
Sbjct: 8364 KYSVTKLIEGKEYLFRVRAENRFGPGPPCVS-KPLVAKDPFGPP---------DAPDKPI 8413
Query: 988 GEPV--NLLIPFQGKPR----PQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSG 1041
E V N ++ +P+ P + + E + + S N L +
Sbjct: 8414 VEDVTSNSMLVKWNEPKDNGSPILGYWLEKREVNSTHWSRVNKSLLNALKANVDGLLEGL 8473
Query: 1042 TYQVTVRIENMEDKATL--------VLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVG 1093
TY V EN + P PP RVTD + LEW+PP G
Sbjct: 8474 TYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIP-RVTDTSSTTIELEWEPPAFNG 8532
Query: 1094 NTELWGYTVQKADKKTMEWFTVLEHYRRTH-CVVPELIIGNGYYFRVFSQNMVGFSDRAA 1152
E+ GY V K T EW E + V E+ G Y RV + N G
Sbjct: 8533 GGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGEGPPGE 8592
Query: 1153 TTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKI 1212
T +PV + P EPP + LD S ++AG T + V G P P
Sbjct: 8593 T--QPVTVAEP---QEPPAVE-LDVSVKGGI-------QIMAGKTLRIPAVVTGRPVPTK 8639
Query: 1213 SWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
W K +L +D R + + L I+ D G YV ATN G R+EV
Sbjct: 8640 VWTKEEGELDKD-RVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEV 8696
Score = 92.4 bits (228), Expect = 2e-18
Identities = 101/405 (24%), Positives = 158/405 (39%), Gaps = 35/405 (8%)
Query: 867 IGPPSEPTH-LAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTE 925
+G P PT + ++V+ ++LKW PP+ G + Y +E ++WV + +
Sbjct: 13576 VGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCASAV-Q 13634
Query: 926 HTSILVKDLPTGARLLFRVRAHNMAGPGA-----PVTTTEPVTVQEILQRPRLQLPRH-- 978
T+ V L G FRV A N G G P+ P V + P + RH
Sbjct: 13635 KTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNIVDVRHDS 13694
Query: 979 --LRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQ-PLAGEEVSIRNSPTDTILFIRAA 1035
L T KK G + K R + W + + P+ + + R
Sbjct: 13695 VSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLEYEFRVM 13754
Query: 1036 RRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNT 1095
+G V ++ + + L +D P P+ + +T +V L W P+ G
Sbjct: 13755 AINLAG-----VGKPSLPSEPVVALDPIDPPGKPEVINITRN---SVTLIWTEPKYDGGH 13806
Query: 1096 ELWGYTVQKADKKTMEWFTVLEHYRRTHCV--VPELIIGNGYYFRVFSQNMVGFSDRAAT 1153
+L GY V+K D + W H C V +L+ G Y FR+ ++N G +
Sbjct: 13807 KLTGYIVEKRDLPSKSWMKA-NHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSE 13865
Query: 1154 TKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAML-CCAVRGSPKPKI 1212
+ E + YE P LD P+ L ++ AG T +L ++ G P PK
Sbjct: 13866 STETIICKDE---YEAPTI-VLD----PTIKDGL---TIKAGDTIVLNAISILGKPLPKS 13914
Query: 1213 SWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATN 1257
SW K G D+ ++ S L I+ D G Y ATN
Sbjct: 13915 SWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATN 13959
Score = 91.3 bits (225), Expect = 5e-18
Identities = 65/244 (26%), Positives = 113/244 (46%), Gaps = 6/244 (2%)
Query: 374 QVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAA 433
+V +G ++L V+++ E W+K+GQE+Q S +I L I + D
Sbjct: 2320 KVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHIVID-KQSHMLLIEDMTKEDAGN 2378
Query: 434 YQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVS-EEGAQVKWLKDGVE 492
Y + ST V V + PL+D V+ G + EC+VS + VKW + +
Sbjct: 2379 YSFTIPALGLSTSGRVSVYSVDVITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQ 2438
Query: 493 LTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIA 552
+ ++ + K G + L+IN D G Y L + L V+ K+++ + +
Sbjct: 2439 IKPDDRVQAIVK--GTKQRLVINRTHASDEGPYKLIVGRVETNCNLSVE--KIKIIRGLR 2494
Query: 553 DLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEA 612
DL VF+ E+S + +W KE+ P S+ K+ G+++KLT+ ++ DE
Sbjct: 2495 DLTCTETQNVVFEVELSHSGIDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEG 2554
Query: 613 DYSF 616
Y+F
Sbjct: 2555 KYTF 2558
Score = 91.3 bits (225), Expect = 5e-18
Identities = 107/447 (23%), Positives = 169/447 (37%), Gaps = 74/447 (16%)
Query: 846 VYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYS 905
V A N+ G + + + GPP P ++VS V + W PP G + Y
Sbjct: 17887 VTATNSAGTATENLSVIVLEKPGPPVGPVRF--DEVSADFVVISWEPPAYTGGCQISNYI 17944
Query: 906 VEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQ 965
VE + W + T+I + L TG FR+ A N G AP+ + + V VQ
Sbjct: 17945 VEKRDTTTTTW-HMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKSAPLDS-KAVIVQ 18002
Query: 966 EILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKE----GQPLAGEEVSI 1021
+ P G P + K + V W + G + G +
Sbjct: 18003 YPFKEP----------------GPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQ 18046
Query: 1022 RNSPTDTILFIRAARRVHSGT------------YQVTVRIENME--------DKATLVLQ 1061
+ ++IL+++ + T Y+ V EN+ + +
Sbjct: 18047 KEK--NSILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARD 18104
Query: 1062 VVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTV-LEHYR 1120
D P P+ + +T NV L+WK P G +++ GY V+K D W +
Sbjct: 18105 PCDPPGRPEAIVITRN---NVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVL 18161
Query: 1121 RTHCVVPELIIGNGYYFRVFSQNMVGF------SDRAATTKEPVFIPRPGITYEPPNYKA 1174
T V L+ Y FRV ++N G S A T ++ + P + P YK
Sbjct: 18162 ETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLD---PKYKD 18218
Query: 1175 LDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGED-ARFRMFSKQ 1233
+ V AG T +L +RG P P + W K+G +L E AR + S
Sbjct: 18219 VIV--------------VHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTI 18264
Query: 1234 GVLTLEIRKPCPFDGGIYVCRATNLQG 1260
TL ++ DGG Y+ + +N+ G
Sbjct: 18265 QKTTLVVKDCIRTDGGQYILKLSNVGG 18291
Score = 90.9 bits (224), Expect = 7e-18
Identities = 68/227 (29%), Positives = 112/227 (49%), Gaps = 8/227 (3%)
Query: 386 ELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSL--ADDAAYQCVVGGEKC 443
E+++ D +W G+ ++ S + I ++ G KR LT+ + L A + YQ +
Sbjct: 4922 EISEADIPGQWKLKGELLRPSPTCEI-KAEGGKRFLTLHKVKLDQAGEVLYQAL--NAIT 4978
Query: 444 STELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRF 503
+ L VKE + PL+D V ++ FEC ++ E A V W K G ++ + K+
Sbjct: 4979 TAILTVKEIELDFAVPLKDVTVPERRQARFECVLTRE-ANVIWSK-GPDIIKSSD-KFDI 5035
Query: 504 KKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAV 563
DG++H L+IN++ +D G Y G + A L V +L+ + D V + A
Sbjct: 5036 IADGKKHILVINDSQFDDEGVYTAEVEGKKTSARLFVTGIRLKFMSPLEDQTVKEGETAT 5095
Query: 564 FKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPAD 610
F CE+S E + VW KN +L + +S G+ HKL + +VT D
Sbjct: 5096 FVCELSHEKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDD 5142
Score = 90.5 bits (223), Expect = 9e-18
Identities = 108/430 (25%), Positives = 157/430 (36%), Gaps = 64/430 (14%)
Query: 868 GPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHT 927
GPP P + D+ SL W P G + Y VE C +WV AL +T+ T
Sbjct: 12496 GPPQPP--FDISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTK-T 12552
Query: 928 SILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKV 987
S V L G +FRVRA N G P+T+ P+ + Q
Sbjct: 12553 SCRVGKLIPGQEYIFRVRAENRFGISEPLTS-----------------PKMVAQFPFGVP 12595
Query: 988 GEPVNLLIPFQGKPRPQVTWTKE----GQPLAGEEVSIRNSPTDTILFIRAARR-VHSGT 1042
EP N + K V W + G P+ G I +++L+++A V S
Sbjct: 12596 SEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIG--YLIERKERNSLLWVKANDTLVRSTE 12653
Query: 1043 YQVTVRIENME----------------DKATLVLQVVDKPSPPQDLRVTDAWGLNVALEW 1086
Y +E +E K T + PP V D V+L W
Sbjct: 12654 YPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIW 12713
Query: 1087 KPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNG------YYFRVF 1140
P+ G +++ GY V+ +W + H + E G Y FR
Sbjct: 12714 ARPKHDGGSKIIGYFVEACKLPGDKW---VRCNTAPHQIPQEEYTATGLEEKAQYQFRAI 12770
Query: 1141 SQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAML 1200
++ V S + + +PV I + PP +D S A +V AG L
Sbjct: 12771 ARTAVNISPPSEPS-DPVTILAENV---PPR---IDLSVAMKSLL-----TVKAGTNVCL 12818
Query: 1201 CCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQG 1260
V G P P +SW K+G L +M ++ + TLE+ D G Y A N G
Sbjct: 12819 DATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSG 12878
Query: 1261 EARCECRLEV 1270
+L+V
Sbjct: 12879 SKSATIKLKV 12888
Score = 90.5 bits (223), Expect = 9e-18
Identities = 111/461 (24%), Positives = 182/461 (39%), Gaps = 71/461 (15%)
Query: 727 VETTKDRSIFTVEGAEKEDEGVYTVTVKNPVG---EDQVNLTVKVIDVPDAPAAPKISNV 783
++ TK ++ EG E E + V+ +N VG +V+ D D P P+ +
Sbjct: 18062 IQDTKFKTTGLDEGLEYE----FKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAIVI 18117
Query: 784 GEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYE 843
++ T++W+ PAYDGG I GYI+E+K RWM+ +F + E ++E YE
Sbjct: 18118 TRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGLVEDQRYE 18177
Query: 844 MRVYAVNAIG-MSRPSPASQPFM---PIGPPSEPTHLAVEDV-----SDTTV---SLKWR 891
RV A NA G S PS +S I P+ +DV +T V ++ +
Sbjct: 18178 FRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVHAGETFVLEADIRGK 18237
Query: 892 PPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAG 951
P V DG +E ++ + T+++VKD + ++ N+ G
Sbjct: 18238 PIPDV-VWSKDGKELEETAARME-----IKSTIQKTTLVVKDCIRTDGGQYILKLSNVGG 18291
Query: 952 PGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVN-LLIPFQGKPRPQVTWTKE 1010
T + P+TV ++L RP G P L + + + W
Sbjct: 18292 -----TKSIPITV-KVLDRP----------------GPPEGPLKVTGVTAEKCYLAWNPP 18329
Query: 1011 GQPLAGEEVS---IRNSPTDTILFIRAARRVHSGTYQVTVRI------------------ 1049
Q G +S I T + + + + V + Y+VT +
Sbjct: 18330 LQD-GGANISHYIIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGIG 18388
Query: 1050 ENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKT 1109
E +E P PP V+ ++ + W P D G TE+ GY ++K DK+
Sbjct: 18389 EPLESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEG 18448
Query: 1110 MEWFTV-LEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSD 1149
+ W + V L G+ Y FRV ++N G +
Sbjct: 18449 VRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGE 18489
Score = 89.0 bits (219), Expect = 3e-17
Identities = 135/650 (20%), Positives = 234/650 (36%), Gaps = 98/650 (15%)
Query: 661 VVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPD------------APEDTGDS 708
V A NK + P+ DP V+ Q T + AP P P PE G S
Sbjct: 21629 VSAVNKFGVGRPLDSDP---VVAQIQYTVPD-APGIPEPSNITGNSITLTWARPESDGGS 21684
Query: 709 D--EWVFDKKLLCETEGRVRVETTKDRSI----FTVEGAEKEDEGVYTVTVKNPVGEDQV 762
+ +++ +++ E + V+ R I F V G + +E + V +N G
Sbjct: 21685 EIQQYILERR---EKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVGPA 21741
Query: 763 NLTVKVI------DVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSY 816
+ ++I + P P K+++ + + +++W P +DGG I+GYI+E K
Sbjct: 21742 SGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLG 21801
Query: 817 RWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIG----------MSRPSPASQPFMP 866
W ++N + + + + G Y+ RV A+N G + + P +
Sbjct: 21802 DWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIKAVDRLTAPELD 21861
Query: 867 IGPPSEPTHLAVEDVS---------DTTVSLKWRPPE-----RVGAGGLDGYSVEYCPEG 912
I + TH+ S T + W P+ R D +S E
Sbjct: 21862 IDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADIHTTDSFST-LTVEN 21920
Query: 913 CSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQ--R 970
C+ A LT V++ + F V+ + GP P+T + L
Sbjct: 21921 CNRNDAGKYTLT------VENNSGSKSITFTVKVLDTPGPPGPITFKDVTRGSATLMWDA 21974
Query: 971 PRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTIL 1030
P L + + +K + + +W + + + +
Sbjct: 21975 PLLDGGARIHHYVVEK-------------REASRRSWQVISEKCTRQIFKVNDLAEGVPY 22021
Query: 1031 FIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQ 1090
+ R + Y V E E + ++P+PP+ L V D + L W P
Sbjct: 22022 YFRVSA---VNEYGVGEPYEMPEP-----IVATEQPAPPRRLDVVDTSKSSAVLAWLKPD 22073
Query: 1091 DVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDR 1150
G + + GY ++ K + W H ++ V L+ Y FRV ++N G+S+
Sbjct: 22074 HDGGSRITGYLLEMRQKGSDFWVEA-GHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEP 22132
Query: 1151 AATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKP 1210
V I P I EP ++ T L+ AG + + G P P
Sbjct: 22133 REAFSS-VIIKEPQI--EPT-------ADLTGITNQLITCK--AGSPFTIDVPISGRPAP 22180
Query: 1211 KISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQG 1260
K++W + L E R + + + TL ++ D G Y N G
Sbjct: 22181 KVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAG 22230
Score = 88.2 bits (217), Expect = 5e-17
Identities = 100/421 (23%), Positives = 169/421 (40%), Gaps = 41/421 (9%)
Query: 359 EKKSTAFQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAK 418
E + F+K ++ + K + E+++ D V+W+K+ QE+Q++ I +
Sbjct: 3008 EARHIEFRKHIKDIKVLEK-KRAMFECEVSEPDITVQWMKDDQELQITDRIKIQKEKYVH 3066
Query: 419 RTLTISQCSLADDAAYQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVS 478
R L I ++D Y V GG + +LFV+ V I ++ V+ QR E EV+
Sbjct: 3067 RLL-IPSTRMSDAGKYTVVAGGNVSTAKLFVEGRDVRIRSIKKEVQVIEKQRAVVEFEVN 3125
Query: 479 EEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAEL 538
E+ W KDG+E+ + ++++ + + H + I+E DAG Y ++ L
Sbjct: 3126 EDDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVTL 3185
Query: 539 IVQ-EKKLEVYQSIADLMVGAKDQAVFKCEVSDENVRGV-WLKNGKELVPDSRIKVSHIG 596
V + +V Q + + V + A F +S + W K + L + K H G
Sbjct: 3186 YVNAPEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDG 3245
Query: 597 RVHKLTIDDVTPADEADYSFVPEG--FACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGR 654
+ + L + + P D A Y+ + SA L +EV P QE P
Sbjct: 3246 QEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLS-VEVPEVVSPDQEMPVYPPAIITP 3304
Query: 655 IPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFD 714
+ DT V G R +SG + K D
Sbjct: 3305 LQDT-VTSEGQPARFQCRVSGTDLKVSWYSK----------------------------D 3335
Query: 715 KKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKV-IDVPD 773
KK+ + R+ +D + A EDEG YT N VG QV+ T + ++ P+
Sbjct: 3336 KKI--KPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVG--QVSSTANLSLEAPE 3391
Query: 774 A 774
+
Sbjct: 3392 S 3392
Score = 86.7 bits (213), Expect = 1e-16
Identities = 71/263 (26%), Positives = 119/263 (45%), Gaps = 10/263 (3%)
Query: 375 VSKGHKIRLTVELADHDA-EVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAA 433
V +G K L +++ D VKW N ++I+ G K+ L I++ +D+
Sbjct: 2410 VIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVK-GTKQRLVINRTHASDEGP 2468
Query: 434 YQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVEL 493
Y+ +VG + + L V++ + I R L D Q V FE E+S G V W E+
Sbjct: 2469 YKLIVGRVETNCNLSVEK--IKIIRGLRDLTCTETQNVVFEVELSHSGIDVLWNFKDKEI 2526
Query: 494 TREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIAD 553
+ + KY+ + G+ + L + M +D G Y +L V + + + D
Sbjct: 2527 --KPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTFYAGENMTSGKLTVAGGAIS--KPLTD 2582
Query: 554 LMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEAD 613
V +AVF+CEV++ + +G WL++GK L + I+ G +L I D +
Sbjct: 2583 QTVAESQEAVFECEVANPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGE 2642
Query: 614 YSFVPEGFACNLSAKLHFMEVKI 636
Y++ + SAKL VKI
Sbjct: 2643 YTY--KVATSKTSAKLKVEAVKI 2663
Score = 86.7 bits (213), Expect = 1e-16
Identities = 156/799 (19%), Positives = 296/799 (37%), Gaps = 121/799 (15%)
Query: 1 MPEPGKKPVSAFSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASN--KYGLA 58
+P ++ F K S E+A + V E+ RA +V W + G + + ++ +
Sbjct: 26215 LPVSAPPKITQFLKAEASKEIAKLT-CVVESSVLRAK-EVTWYKDGKKLKENGHFQFHYS 26272
Query: 59 TEGTRHTLTVREVGPADQGSYAVI----AGSSKVKFDLKVIEAEKAEPMLAPAPAPAEAT 114
+GT + L + + +DQG Y G+SK +A
Sbjct: 26273 ADGT-YELKINNLTESDQGEYVCEISGEGGTSKTNLQFM-----------------GQAF 26314
Query: 115 GAPGEAPAPAAELGESAPSPKGSSSAALNGPTPGAPDDPIG---LFVMRPQDGEVTVGGS 171
+ E + +E +S K + S P AP+ PI + V QD V+
Sbjct: 26315 KSIHEKVSKISETKKS--DQKTTESTVTRKTEPKAPE-PISSKPVIVTGLQDTTVSSDSV 26371
Query: 172 ITFSARVAGASLLKPPVVKWFK-GKWVDLSSKVGQHLQLHDSYDRASKVYLFELHITDAQ 230
F+ + G P W K GK + K S D+ + E+H TD
Sbjct: 26372 AKFAVKATGEPR---PTAIWTKDGKAITQGGKYKL------SEDKGG--FFLEIHKTDTS 26420
Query: 231 PAFTGSYRCEVSTKDKFDCSNFNLTVHEAMGTGDLDLLSAFRRTSLAGGGRRISDSHEDT 290
+ G Y C V S+ LT+ +A+ + +S + + + + +
Sbjct: 26421 DS--GLYTCTVKNSAGSVSSSCKLTI-KAIKDTEAQKVSTQKTSEITPQKKAVVQEEISQ 26477
Query: 291 GILDFSSLLKKRDSFRTPRDSKLEAPAEEDVWEILRQAPPSEYERIAFQYGVTDLRGMLK 350
L S +K ++ + + E ++ + E ++++ + E+ +T
Sbjct: 26478 KALR-SEEIKMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEEITKT----- 26531
Query: 351 RLKGMRRDEKKSTAFQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKY 410
+E ++ A K +++G ++ L +A +VKW+ NG E+ S +Y
Sbjct: 26532 ---SQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAGA-TDVKWVLNGVELTNS-EEY 26586
Query: 411 IFESIGAKRTLTISQCSLADDAAYQCV----VGGEKCSTELF----VKEPPVLITRPLED 462
+ G+ +TLTI Q S D+ C+ G KC +L + + P I++P
Sbjct: 26587 RYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTLSKELSDAPAFISQP-RS 26645
Query: 463 QLVMVGQRVEFECEVS-EEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLED 521
Q + GQ V F CE+S E +++W K+ + ++ + + L I A + D
Sbjct: 26646 QNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVS--ISRSRNVYSLEIRNASVSD 26703
Query: 522 AGHYAL--------CTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDENV 573
+G Y + C++ + +V+E EV ++ + S ++V
Sbjct: 26704 SGKYTIKAKNFRGQCSATASLMVLPLVEEPSREV-------VLRTSGDTSLQGSFSSQSV 26756
Query: 574 RGVWLKNGKELVPDSRIKVSHIGRVH--KLTIDDVTPADEADYSFVPEGF--ACNLSAKL 629
+ K S S + + ++ ++ E+ F N++
Sbjct: 26757 QMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQLE 26816
Query: 630 HFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQ 689
+ R PPKI +P I + G L + +G+P P V W
Sbjct: 26817 SSTSKMLKAGIRGIPPKIE-----ALPSDISIDEGKVLTVACAFTGEPTPEVTWSCG--- 26868
Query: 690 GNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVY 749
+K+ + +GR +E T D + + +K+D G+Y
Sbjct: 26869 ------------------------GRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLY 26904
Query: 750 TVTVKNPVGEDQVNLTVKV 768
T+++ N G D + + +
Sbjct: 26905 TLSLGNEFGSDSATVNIHI 26923
Score = 86.3 bits (212), Expect = 2e-16
Identities = 67/265 (25%), Positives = 115/265 (43%), Gaps = 6/265 (2%)
Query: 375 VSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAY 434
V +G EL+ V W KN ++ S + + S G L + + +L D +
Sbjct: 5088 VKEGETATFVCELSHEKMHVVWFKNDAKLHTSRT-VLISSEGKTHKLEMKEVTLDDISQI 5146
Query: 435 QCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELT 494
+ V + +L V E T L D+ + + +CEVS++ VKW KDG E+
Sbjct: 5147 KAQVKELSSTAQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVSKD-VPVKWFKDGEEIV 5205
Query: 495 REETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADL 554
KY K DG R L I +A L+D G Y + A + V+ + ++V + + +
Sbjct: 5206 PSP--KYSIKADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIKVEKPLYGV 5263
Query: 555 MVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADY 614
V + A F+ E+S+ +V G W G+ L ++ G+ H L + + +
Sbjct: 5264 EVFVGETAHFEIELSEPDVHGQWKLKGQPLTASPDCEIIEDGKKHILILHNCQLGMTGEV 5323
Query: 615 SFVPEGFACNLSAKLHFMEVKIDFV 639
SF + +A L E+ + F+
Sbjct: 5324 SF--QAANAKSAANLKVKELPLIFI 5346
Score = 85.9 bits (211), Expect = 2e-16
Identities = 106/418 (25%), Positives = 147/418 (35%), Gaps = 55/418 (13%)
Query: 868 GPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHT 927
GPP+ P + ++VS V+ W PPE G + Y VE + WV L T
Sbjct: 14663 GPPTGP--IKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVE-LATTVIRT 14719
Query: 928 SILVKDLPTGARLLFRVRAHNMAGPGAPVTTT-----EPVTVQEILQRPRLQLPRHLRQT 982
+ L TG FRV+A N G G +T+ P V P++ T
Sbjct: 14720 TYKATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMT 14779
Query: 983 IQ-----KKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARR 1037
I G P+ L + K R + W + L + + TD I
Sbjct: 14780 ISWHEPLSDGGSPI-LGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGI-------- 14830
Query: 1038 VHSGTYQVTVRIENMEDKAT--------LVLQVVDKPSPPQDLRVTDAWGLNVALEWKPP 1089
Y+ V ENM K+ L L +D P P L +T V L+W P
Sbjct: 14831 ----AYEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRH---TVTLKWAKP 14883
Query: 1090 QDVGNTELWGYTVQKADKKTMEWFTV-LEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFS 1148
+ G ++ Y V+K D W + V L Y FRV ++N
Sbjct: 14884 EYTGGFKITSYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKN----- 14938
Query: 1149 DRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVI---AGYTAMLCCAVR 1205
AA P P IT D EAP + + + AG L V
Sbjct: 14939 --AAGAISPPSEPSDAITCR-------DDVEAPKIKVDVKFKDTVILKAGEAFRLEADVS 14989
Query: 1206 GSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEAR 1263
G P P + W K+G +L A+ + L + D G Y ATN G A+
Sbjct: 14990 GRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGGFAK 15047
Score = 85.9 bits (211), Expect = 2e-16
Identities = 99/432 (22%), Positives = 160/432 (37%), Gaps = 45/432 (10%)
Query: 846 VYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYS 905
+ N +G S PP P +DVS +++L W PP G + Y
Sbjct: 16805 ITVANVVGQKTASIEIVTLDKPDPPKGPVKF--DDVSAESITLSWNPPLYTGGCQITNYI 16862
Query: 906 VEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQ 965
V+ + W + T++ V L TG FR+ A N G + + +P+ Q
Sbjct: 16863 VQKRDTTTTVW-DVVSATVARTTLKVTKLKTGTEYQFRIFAENRYGQSFALES-DPIVAQ 16920
Query: 966 EILQRPRLQ----LPRHLRQTIQKKVGEPVN------LLIPFQGKPRPQVTWTKEGQPLA 1015
+ P + ++ + EPVN + + K R + WTK + +
Sbjct: 16921 YPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKTII 16980
Query: 1016 GEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVT 1075
+ + + I + RV++ V V + + + D P P+ + V
Sbjct: 16981 HDTQFKAQNLEEGIEY---EFRVYAENI-VGVGKASKNSECYVARDPCDPPGTPEPIMVK 17036
Query: 1076 DAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTV-LEHYRRTHCVVPELIIGNG 1134
+ L+W P G + + GY V+K D W + T V L
Sbjct: 17037 RN---EITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQR 17093
Query: 1135 YYFRVFSQNMVGFSDRAA------TTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLV 1188
Y FRV ++N G + + T K+ V +PR S P F +V
Sbjct: 17094 YEFRVIAKNAAGAISKPSDSTGPITAKDEVELPR--------------ISMDPKFRDTIV 17139
Query: 1189 NRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDG 1248
V AG T L V G P P I W + ++ E AR + + L ++ DG
Sbjct: 17140 ---VNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDG 17196
Query: 1249 GIYVCRATNLQG 1260
G Y+ RA+N+ G
Sbjct: 17197 GQYILRASNVAG 17208
Score = 85.5 bits (210), Expect = 3e-16
Identities = 109/404 (26%), Positives = 150/404 (37%), Gaps = 61/404 (15%)
Query: 847 YAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSV 906
Y V A + A + P +L + DVS ++ W PPE G + Y +
Sbjct: 11777 YVVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYIL 11836
Query: 907 EYCPEGCSEWVA-ALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQ 965
E C W + LT T+ V L G +FRVRA N G G P T ++PV
Sbjct: 11837 EKCETKRMVWSTYSATVLTPGTT--VTRLIEGNEYIFRVRAENKIGTGPP-TESKPV--- 11890
Query: 966 EILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKE----GQPLAG----- 1016
+ +T K G P + K V W G+ + G
Sbjct: 11891 -------------IAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLEK 11937
Query: 1017 -EEVSIRNSPTDTILFIRAARRVHS----GTYQVTVRIEN--------MEDKATLVLQVV 1063
E+ S R P + +V + YQ V+ EN + + + +
Sbjct: 11938 KEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPI 11997
Query: 1064 DKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQK----ADKKTMEWF---TVL 1116
+ P PP + RV D ++ L W P G + GY V+ AD E +
Sbjct: 11998 EPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAA 12057
Query: 1117 EHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALD 1176
R V L Y FRV +QN VG R A KE + +P EPP LD
Sbjct: 12058 AQLVRKEFTVTSLDENQEYEFRVCAQNQVGIG-RPAELKEAI---KPKEILEPPEID-LD 12112
Query: 1177 FSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLD 1220
S + LV V AG L VRG P PK++W K G+D
Sbjct: 12113 AS-----MRKLV--IVRAGCPIRLFAIVRGRPAPKVTWRKVGID 12149
Score = 85.5 bits (210), Expect = 3e-16
Identities = 110/462 (23%), Positives = 181/462 (39%), Gaps = 59/462 (12%)
Query: 769 IDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQE 828
+D D P P N+ + T++W P Y GG I YI+E++ + RW++ NF I E
Sbjct: 14857 LDPIDPPGKPVPLNITRHTVTLKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILE 14916
Query: 829 LSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSL 888
+ E YE RV A NA G P + E + V+ TV L
Sbjct: 14917 NEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVIL 14976
Query: 889 KWRPPERVGA--GGLDGYSVEYCPEGCS-EWVAALQGLTE--HTSILVKDL--------- 934
K R+ A G ++E+ +G E A L+ T+++ KD
Sbjct: 14977 KAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYT 15036
Query: 935 -----PTG-ARLLFRVRAHNMAG-PGAPVTTTEPVTVQEILQ-RPRLQLPRHLRQTIQKK 986
P G A+ +F V+ + G P P+ TE + + +L P L
Sbjct: 15037 LTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFPPLD-----------D 15085
Query: 987 VGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRN--SPTDTILFIRAARRVHSGTYQ 1044
G ++ I Q + ++ WT + ++ + + I + A + G
Sbjct: 15086 GGAKIDHYI-VQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYGVG--- 15141
Query: 1045 VTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQK 1104
E +E + L + P PP++ VT ++ + W P G +E+ Y V++
Sbjct: 15142 -----EPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVER 15196
Query: 1105 ADKKTMEWFTV-LEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTK-----EPV 1158
DK W + V L G+ Y FR+ ++N G S + T+ + V
Sbjct: 15197 RDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTV 15256
Query: 1159 FIPRPGITYEPPNYKALDFSEAP---SFTQPLVN-RSVIAGY 1196
F P P P N + LD S + ++ +P+ + S I GY
Sbjct: 15257 FKPGP-----PGNPRVLDTSRSSISIAWNKPIYDGGSEITGY 15293
Score = 85.5 bits (210), Expect = 3e-16
Identities = 66/214 (30%), Positives = 97/214 (45%), Gaps = 18/214 (8%)
Query: 1064 DKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVL-EHYRRT 1122
+KP P +T + + WKPP G ++ Y ++K +KK +W +V E R T
Sbjct: 24326 EKPGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRET 24385
Query: 1123 HCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPS 1182
V LI G Y FRV +N+ G S+ + + EP+ P+ + + P++K
Sbjct: 24386 VFSVKNLIEGLEYEFRVKCENLGGESEWSEIS-EPI-TPKSDVPIQAPHFK--------- 24434
Query: 1183 FTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDA---RFRMFSKQGVLTLE 1239
+ L N +V A L C V G PKP + W++ G ++ D R + F K G L
Sbjct: 24435 --EELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEF-KGGYHQLI 24491
Query: 1240 IRKPCPFDGGIYVCRATNLQGEARCECRLEVRVP 1273
I D +Y RATN G LEV VP
Sbjct: 24492 IASVTDDDATVYQVRATNQGGSVSGTASLEVEVP 24525
Score = 82.0 bits (201), Expect = 3e-15
Identities = 91/374 (24%), Positives = 142/374 (37%), Gaps = 41/374 (10%)
Query: 868 GPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHT 927
GPP+ P + ++++ T++++ W PPE G L GY VE W+ + +T T
Sbjct: 23336 GPPTGP--IKIDEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRST 23393
Query: 928 SILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKV 987
+ L G +FRV A N G G+ + + V E R+ P Q
Sbjct: 23394 FKFTR-LTEGNEYVFRVAATNRFGIGSYLQSE----VIECRSSIRIPGPPETLQIFDVSR 23448
Query: 988 GEPVNLLIPFQGKPRPQVTW--TKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQV 1045
P + QVT + + A V + P T+ R+ Y+
Sbjct: 23449 DGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPV-TMTRYRSTGLTEGLEYEH 23507
Query: 1046 TVRIENME--------DKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTEL 1097
V N K + + + P PQ+ RVTD +V+L W P+D G +++
Sbjct: 23508 RVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKV 23567
Query: 1098 WGYTVQKADKKTMEWF------TVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRA 1151
GY ++ EW T + Y TH +P+ G Y FRV + N G
Sbjct: 23568 TGYLIEMQKVDQHEWTKCNTTPTKIREYTLTH--LPQ---GAEYRFRVLACNAGG----- 23617
Query: 1152 ATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPK 1211
EP +P E Y + E + + + R G L ++G P P
Sbjct: 23618 --PGEPAEVPGTVKVTEMLEYPDYELDER--YQEGIFVRQ---GGVIRLTIPIKGKPFPI 23670
Query: 1212 ISWFKNGLDLGEDA 1225
W K G D+ + A
Sbjct: 23671 CKWTKEGQDISKRA 23684
Score = 81.3 bits (199), Expect = 6e-15
Identities = 100/418 (23%), Positives = 150/418 (35%), Gaps = 61/418 (14%)
Query: 870 PSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSI 929
P P + + +VS +L W PP G + Y +E W + + +
Sbjct: 13976 PGPPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHV 14035
Query: 930 LVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGE 989
K L G +FRV A N G G PV + EPV + + P G
Sbjct: 14036 ATK-LIQGNEYIFRVSAVNHYGKGEPVQS-EPVKMVDRFGPP----------------GP 14077
Query: 990 PVNLLIPFQGKPRPQVTWTKE----GQPLAGEEVSIRNSPTDTILFIRAARRVHS----- 1040
P + K V+W + G + G V R + + ++RA + S
Sbjct: 14078 PEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKS--LRWVRAIKTPVSDLRCK 14135
Query: 1041 -------GTYQVTVRIENME--------DKATLVLQVVDKPSPPQDLRVTDAWGLNVALE 1085
TY+ V EN + L+ P PP + VTD + +L
Sbjct: 14136 VTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLA 14195
Query: 1086 WKPPQDVGNTELWGYTVQKADKKTMEWF--TVLEHYRRTHCVVPELIIGNGYYFRVFSQN 1143
W P G E+ GY V+ W T R T VVP+L Y FR+ + N
Sbjct: 14196 WGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAIN 14255
Query: 1144 MVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCA 1203
G EP IP I A DF + LV R AG + +
Sbjct: 14256 DAGVG-------EPAVIPDVEIVERE---MAPDFELDAELRRTLVVR---AGLSIRIFVP 14302
Query: 1204 VRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGE 1261
++G P P+++W K+ ++L A + + L I + +D G +V N G+
Sbjct: 14303 IKGRPAPEVTWTKDNINLKNRANIE--NTESFTLLIIPECNRYDTGKFVMTIENPAGK 14358
Score = 78.2 bits (191), Expect = 5e-14
Identities = 70/236 (29%), Positives = 112/236 (47%), Gaps = 14/236 (5%)
Query: 396 WLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVV---GGEKCST-ELFVKE 451
W+K+G I+ S K+ F + G R L I L+D Y CV+ EK ST +L V+E
Sbjct: 4654 WMKDGSNIRES-PKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEE 4712
Query: 452 PPVLITRPLEDQLVMV-GQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKKDGQRH 510
PV + LE+++ +V GQ + CE+++E V W KDG ++ E+ + G
Sbjct: 4713 LPVRFVKTLEEEVTVVKGQPLYLSCELNKE-RDVVWRKDG-KIVVEKPGRIVPGVIGLMR 4770
Query: 511 HLIINEAMLEDAGHYALCTSGGQAL----AELIVQEKKLEVYQSIADLMVGAKDQAVFKC 566
L IN+A DAG Y + L +V+ + + + I D V K A+F C
Sbjct: 4771 ALTINDADDTDAGTYTVTVENANNLECSSCVKVVEVIRDWLVKPIRDQHVKPKGTAIFAC 4830
Query: 567 EVSDENVRGVWLKNGKEL--VPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEG 620
+++ + W K E+ P+ + ++ G L I + P D A+Y+ EG
Sbjct: 4831 DIAKDTPNIKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEG 4886
Score = 77.8 bits (190), Expect = 6e-14
Identities = 98/433 (22%), Positives = 154/433 (35%), Gaps = 42/433 (9%)
Query: 847 YAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSV 906
Y + A S A+ + P P + + + L W PP G + Y V
Sbjct: 12869 YTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIV 12928
Query: 907 EYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQE 966
+ W A + TS V+ L G FR+ A N G G PV T EP +
Sbjct: 12929 DKRETSRPNW-AQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFT-EPAIAKN 12986
Query: 967 ILQRPRLQLPRHLRQTIQKKV-----------GEPVNLLIPFQGKPRPQVTWTKEGQ-PL 1014
P P + + + G P+ + + + V WTK + P+
Sbjct: 12987 PYDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYL-LEKRETQAVNWTKVNRKPI 13045
Query: 1015 AGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRV 1074
+ T R +G + + KA P PP +V
Sbjct: 13046 IERTLKATGLQEGTEYEFRVTAINKAGPGK-----PSDASKAAYARDPQYPPGPPAFPKV 13100
Query: 1075 TDAWGLNVALEWKPPQDVGNTELWGYTVQ--KADKKTMEWFTVLEHYRRTHCVVPELIIG 1132
D +V+L W P G + + GY V+ +AD + ++ ++T V L+
Sbjct: 13101 YDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMED 13160
Query: 1133 NGYYFRVFSQNMVGFSDRAATTKE----PVFIPRPGITYEPPNYKALDFSEAPSFTQPLV 1188
Y FRV++ N +G+SD + + + IP G LD + L+
Sbjct: 13161 TQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEG---------ELD----ADLRKTLI 13207
Query: 1189 NRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDG 1248
R AG T L V+G P PKI+W K ++L + + S L +D
Sbjct: 13208 LR---AGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDA 13264
Query: 1249 GIYVCRATNLQGE 1261
G Y+ N G+
Sbjct: 13265 GKYILTLENSCGK 13277
Score = 77.4 bits (189), Expect = 8e-14
Identities = 65/250 (26%), Positives = 112/250 (44%), Gaps = 8/250 (3%)
Query: 375 VSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAY 434
V++ + E+A+ D++ +WL++G+ + ++ + ES G KR L I+ L D Y
Sbjct: 2585 VAESQEAVFECEVANPDSKGEWLRDGKHLPLTNN-IRSESDGHKRRLIIAATKLDDIGEY 2643
Query: 435 QCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQ-VKWLKDGVEL 493
V K S +L V+ V I + L++ V Q F E++ + V+W+K+GV L
Sbjct: 2644 TYKVATSKTSAKLKVEA--VKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVL 2701
Query: 494 TREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIAD 553
E KY G + L I + D Y A A L V+ K + + D
Sbjct: 2702 ESNE--KYAISVKGTIYSLRIKNCAIVDESVYGFRLGRLGASARLHVETVK--IIKKPKD 2757
Query: 554 LMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEAD 613
+ F+ VS + V W E+ P + ++ +VHKL + +++P+D +
Sbjct: 2758 VTALENATVAFEVSVSHDTVPVKWFHKSVEIKPSDKHRLVSERKVHKLMLQNISPSDAGE 2817
Query: 614 YSFVPEGFAC 623
Y+ V C
Sbjct: 2818 YTAVVGQLEC 2827
Score = 77.4 bits (189), Expect = 8e-14
Identities = 52/242 (21%), Positives = 99/242 (40%), Gaps = 3/242 (1%)
Query: 374 QVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAA 433
+V + + + E++ +WLK QEI ++ G K ++ I + D+A
Sbjct: 5353 KVFEKDEAKFECEVSREPKTFRWLKGTQEIT-GDDRFELIKDGTKHSMVIKSAAFEDEAK 5411
Query: 434 YQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVEL 493
Y + S +L ++ + PL+D + F E+S + +VKW K+ L
Sbjct: 5412 YMFEAEDKHTSGKLIIEGIRLKFLTPLKDVTAKEKESAVFTVELSHDNIRVKWFKNDQRL 5471
Query: 494 TREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIAD 553
T + +G+ H + + ++D + G + A+L V E + D
Sbjct: 5472 --HTTRSVSMQDEGKTHSITFKDLSIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQD 5529
Query: 554 LMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEAD 613
KD+ + +CE+S + W K+GKE+ P + G+ L + +D
Sbjct: 5530 YTGVEKDEVILQCEISKADAPVKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQ 5589
Query: 614 YS 615
Y+
Sbjct: 5590 YT 5591
Score = 71.6 bits (174), Expect = 4e-12
Identities = 60/195 (30%), Positives = 92/195 (47%), Gaps = 17/195 (8%)
Query: 439 GGEKCSTEL----FVKEPPVLITRPLEDQLV----MVGQRVEFECEVSEEGAQVKWLKDG 490
GGEK E +K P+ + ++D ++ VG FEC VS A W+KDG
Sbjct: 4599 GGEKPPDEAPFTYQLKAVPLKFVKEIKDIILTESEFVGSSAIFECLVSPSTAITTWMKDG 4658
Query: 491 VELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQ----ALAELIVQEKKLE 546
+ E+ K+RF DG+ L I + L DAG Y G + A+L+V+E +
Sbjct: 4659 SNI--RESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEELPVR 4716
Query: 547 VYQSIADLMVGAKDQAVF-KCEVSDENVRGVWLKNGKELV-PDSRIKVSHIGRVHKLTID 604
+++ + + K Q ++ CE++ E VW K+GK +V RI IG + LTI+
Sbjct: 4717 FVKTLEEEVTVVKGQPLYLSCELNKER-DVVWRKDGKIVVEKPGRIVPGVIGLMRALTIN 4775
Query: 605 DVTPADEADYSFVPE 619
D D Y+ E
Sbjct: 4776 DADDTDAGTYTVTVE 4790
Score = 70.9 bits (172), Expect = 8e-12
Identities = 62/255 (24%), Positives = 106/255 (41%), Gaps = 6/255 (2%)
Query: 386 ELADHDAEVKWLKNGQEIQMS-GSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCS 444
++A +KW K EI K G L I D A Y + G++
Sbjct: 4831 DIAKDTPNIKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEGKRYP 4890
Query: 445 TELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFK 504
+L + E V + +P+ED + + F+ E+SE +W G L T + K
Sbjct: 4891 AKLTLGEREVELLKPIEDVTIYEKESASFDAEISEADIPGQWKLKGELLRPSPTCE--IK 4948
Query: 505 KDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVF 564
+G + L +++ L+ AG A L V+E +L+ + D+ V + QA F
Sbjct: 4949 AEGGKRFLTLHKVKLDQAGEVLYQALNAITTAILTVKEIELDFAVPLKDVTVPERRQARF 5008
Query: 565 KCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACN 624
+C ++ E +W K + + + G+ H L I+D DE Y+ EG
Sbjct: 5009 ECVLTRE-ANVIWSKGPDIIKSSDKFDIIADGKKHILVINDSQFDDEGVYTAEVEG--KK 5065
Query: 625 LSAKLHFMEVKIDFV 639
SA+L +++ F+
Sbjct: 5066 TSARLFVTGIRLKFM 5080
Score = 70.1 bits (170), Expect = 1e-11
Identities = 144/622 (23%), Positives = 227/622 (36%), Gaps = 79/622 (12%)
Query: 675 GDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRS 734
G P VI + +T K PA + TG ++ +KK L + T +
Sbjct: 18110 GRPEAIVITRNNVTLKWKKPAYDG--GSKITG----YIVEKKDLPDGRWMKASFTNVLET 18163
Query: 735 IFTVEGAEKEDEGVYTVTVKNPVG------EDQVNLTVK-VIDVPDAPAAPKISNVGEDS 787
FTV G ++ + V +N G + +T + ID P+A PK +V
Sbjct: 18164 EFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVH 18223
Query: 788 CTVQWEPPAYDGGQPILGYILERKKKKSYRWM-RLNF-DLIQELSHEARRMI--EGVVYE 843
+ A G+PI + + K+ R+ IQ+ + + I +G Y
Sbjct: 18224 AGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYI 18283
Query: 844 MRVYAVNAIGMSRPSPASQPFMPI-GPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLD 902
+++ + +G ++ P + + GPP P L V V+ L W PP + G +
Sbjct: 18284 LKL---SNVGGTKSIPITVKVLDRPGPPEGP--LKVTGVTAEKCYLAWNPPLQDGGANIS 18338
Query: 903 GYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPV 962
Y +E W + + K LP G +FRV A N G G P+ + PV
Sbjct: 18339 HYIIEKRETSRLSWTQVSTEVQALNYKVTKLLP-GNEYIFRVMAVNKYGIGEPLESG-PV 18396
Query: 963 TVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKE----GQPLAGEE 1018
T + P G P + K VTW + G + G
Sbjct: 18397 TACNPYKPP----------------GPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYI 18440
Query: 1019 VSIR----------NSPTDTILFIRAARRVHSGTYQVTVRIENME-----DKATLVLQVV 1063
+ R N T T L +R +Y+ V EN + ++ +
Sbjct: 18441 LEKRDKEGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRAC 18500
Query: 1064 DK---PSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEH-- 1118
D P PP + +VTD +V+L W P G + GY V+ + EW T
Sbjct: 18501 DALYPPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTG 18560
Query: 1119 YRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFS 1178
+ V +L Y FR+ + N G + A V R EPP + LD
Sbjct: 18561 LQGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQER----IEPPEIE-LD-- 18613
Query: 1179 EAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTL 1238
+ +V R A T L ++G P+P++ W K L + A+ + S +L +
Sbjct: 18614 --ADLRKVVVLR---ASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVI 18668
Query: 1239 EIRKPCPFDGGIYVCRATNLQG 1260
+ FD G Y N G
Sbjct: 18669 D--NVTRFDSGRYNLTLENNSG 18688
Score = 68.9 bits (167), Expect = 3e-11
Identities = 66/244 (27%), Positives = 95/244 (38%), Gaps = 30/244 (12%)
Query: 1034 AARRVHSGTYQVTVRIENME----------------DKATLVLQVVDKPSPPQDLRVTDA 1077
A + H TY+VT E E + T ++ + PSPP L + D
Sbjct: 14420 ATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDI 14479
Query: 1078 WGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYF 1137
V+L W P+ G +++ GY ++ K + +W T + + CVV L G Y F
Sbjct: 14480 TKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQW-THITTVKGLECVVRNLTEGEEYTF 14538
Query: 1138 RVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYT 1197
+V + N G R+A + RP I E LD Q LV AG
Sbjct: 14539 QVMAVNSAG---RSAPRES-----RPVIVKEQTMLPELDLR---GIYQKLVIAK--AGDN 14585
Query: 1198 AMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATN 1257
+ V G PKP ++W K L + R + L I + D G Y A N
Sbjct: 14586 IKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARN 14645
Query: 1258 LQGE 1261
+ GE
Sbjct: 14646 IVGE 14649
Score = 66.6 bits (161), Expect = 1e-10
Identities = 166/772 (21%), Positives = 275/772 (35%), Gaps = 163/772 (21%)
Query: 577 WLKNGKELVPD--SRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEV 634
W +G+++V D ++ + G L I TP+D +++ V + A S + +
Sbjct: 1444 WFHDGQQIVNDYTHKVVIKEDG-TQSLIIVPATPSDSGEWTVVAQNRAGRSSISVI---L 1499
Query: 635 KIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAP 694
++ V Q P + + G++L + V +G+P P ++W K
Sbjct: 1500 TVEAVEHQVKPMFVEKLKN-----VNIKEGSRLEMKVRATGNPNPDIVWLK--------- 1545
Query: 695 ARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVK 754
+SD V K ++R+E TK + ++ +D YT T
Sbjct: 1546 ------------NSDIIVPHKY------PKIRIEGTKGEAALKIDSTVSQDSAWYTATAI 1587
Query: 755 NPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKK 814
N G D V V V++ P +P I+ R
Sbjct: 1588 NKAGRDTTRCKVNV--------------------EVEFAEP-----EPERKLIIPRG--- 1619
Query: 815 SYRWMRLNFDLIQ--ELSHEARRMIEGVVYEMRVYA-------VNAIGMSRPSPASQP-- 863
+YR + ++ L + + EG +Y+ + ++ + R PA
Sbjct: 1620 TYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGPAHFECR 1679
Query: 864 FMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPE-GCSEWVAALQG 922
PIG P+ + D + + R G LD Y V Y + G A +
Sbjct: 1680 LTPIGDPTMVVEW-LHDGKPLEAANRLRMINEFGYCSLD-YGVAYSRDSGIITCRATNKY 1737
Query: 923 LTEHTS--ILVKD---------LPTGARLLFRVRA-HNMAGPGAPVTTTEPVTVQEILQR 970
T+HTS ++VKD LP G + L R+ MA GA T T Q+ Q+
Sbjct: 1738 GTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVT---TDQKEKQK 1794
Query: 971 PRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLA-GEEVSIRNSPTDTI 1029
P + L + ++ GE G P+P+V W GQ + + +R D I
Sbjct: 1795 PDIVL---YPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRY---DGI 1848
Query: 1030 LFIRAARRVHSGTYQVTVRIEN----MEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALE 1085
++ T +V V EN +E K L +Q +D R L A E
Sbjct: 1849 HYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQ------QREDFRSV----LRRAPE 1898
Query: 1086 WKPPQDVGNTELWGYTVQKADK-----KTMEWFTVLEHYRRTHCVVPELI---------- 1130
+P V + VQK D+ +T E + R TH VPE
Sbjct: 1899 PRPEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKVPEESEELRSKFKRR 1958
Query: 1131 IGNGYYFRV---------------------------FSQNMVGFSDRAATTKEPVFIPRP 1163
GYY + +++ + +A + + IP
Sbjct: 1959 TEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIP-- 2016
Query: 1164 GITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGE 1223
T++P + EAP + + +++V G A V G P P+ W+KNG+ +
Sbjct: 2017 --TFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIER 2074
Query: 1224 DAR-FRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVRVPQ 1274
R + + + V L IR D + +A N+ GE L V+ Q
Sbjct: 2075 SDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQ 2126
Score = 65.5 bits (158), Expect = 3e-10
Identities = 64/246 (26%), Positives = 101/246 (41%), Gaps = 35/246 (14%)
Query: 15 KPRSVEVAAGSPAVFEAETERAGVK-VRWQRGGSDISASNKYGLATEGTRHTLTVREVGP 73
KPRS+ V G A F +T+ V V W R G +S S ++ + T + T + V
Sbjct: 26069 KPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQA 26128
Query: 74 ADQGSYAVIA----GSSKVKFDLKVIEAEKAEPMLAPAPAPAEATGAPGEAPAPAAELGE 129
+D+G+Y+V+ G + +F L + +A E + P ++P P + E
Sbjct: 26129 SDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRV--------KSPEPRVKSPE 26180
Query: 130 SAPSPKGSSSAALNGPTPGAPDDPIGLFVMRPQDGEVTVGGSITFSAR------------ 177
+ SPK S + P +P + + Q V+ IT +
Sbjct: 26181 AVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPVSAPPKITQFLKAEASKEIAKLTC 26240
Query: 178 VAGASLLKPPVVKWFK-GKWVDLSSKVGQHLQLHDSYDRASKVYLFELHITDAQPAFTGS 236
V +S+L+ V W+K GK K H Q H S D +EL I + + G
Sbjct: 26241 VVESSVLRAKEVTWYKDGK----KLKENGHFQFHYSADGT-----YELKINNLTESDQGE 26291
Query: 237 YRCEVS 242
Y CE+S
Sbjct: 26292 YVCEIS 26297
Score = 63.5 bits (153), Expect = 1e-09
Identities = 102/453 (22%), Positives = 153/453 (33%), Gaps = 71/453 (15%)
Query: 820 RLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPAS-------QPFMPIGPPSE 872
R+N ++ L + + + VY V A S + A P +GP
Sbjct: 21505 RMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGP--- 21561
Query: 873 PTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVK 932
+ +++ ++L W P G + Y +E W A ++ E S
Sbjct: 21562 ---IRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAW-ALIEDKCEAQSYTAI 21617
Query: 933 DLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQ---EILQRPRLQLPRHLRQTI------ 983
L G FRV A N G G P+ + +PV Q + P + P ++
Sbjct: 21618 KLINGNEYQFRVSAVNKFGVGRPLDS-DPVVAQIQYTVPDAPGIPEPSNITGNSITLTWA 21676
Query: 984 --QKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSG 1041
+ G + I + + + W K I P F +
Sbjct: 21677 RPESDGGSEIQQYI-LERREKKSTRWVKV----------ISKRPISETRF-KVTGLTEGN 21724
Query: 1042 TYQVTVRIENME--------DKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVG 1093
Y+ V EN + + V+ P PP ++VTD V+LEW P G
Sbjct: 21725 EYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDG 21784
Query: 1094 NTELWGYTVQKADKKTMEWFTV-LEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAA 1152
E+ GY ++ +W V E +T V +L G Y FRV + N G D
Sbjct: 21785 GMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCE 21844
Query: 1153 TTKEPVFIPRPGITYEPPNYKALDFSEAP------SFTQPLVNRSVIAGYTAMLCCAVRG 1206
T KA+D AP +F Q V R AG + L A +G
Sbjct: 21845 VTG---------------TIKAVDRLTAPELDIDANFKQTHVVR---AGASIRLFIAYQG 21886
Query: 1207 SPKPKISWFKNGLDLGEDARFRMFSKQGVLTLE 1239
P P W K +L A LT+E
Sbjct: 21887 RPTPTAVWSKPDSNLSLRADIHTTDSFSTLTVE 21919
Score = 63.5 bits (153), Expect = 1e-09
Identities = 98/435 (22%), Positives = 159/435 (36%), Gaps = 53/435 (12%)
Query: 844 MRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDG 903
++ ++V + + RP P + P + V VS + L W P+ G +
Sbjct: 22231 VKTFSVTVVVIGRPGPVTGP------------IEVSSVSAESCVLSWGEPKDGGGTEITN 22278
Query: 904 YSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAG-----PGAPVTT 958
Y VE G + W + + T I V L FRV + N G AP+
Sbjct: 22279 YIVEKRESGTTAW-QLVNSSVKRTQIKVTHLTKYMEYSFRVSSENRFGVSKPLESAPIIA 22337
Query: 959 TEPVTVQEILQRPRLQLPRHLRQTI--QKKVGEPVNLLIPF--QGKPRPQVTWTKEGQPL 1014
P RP + +I ++ + + +I + + K R + W KE +
Sbjct: 22338 EHPFVPPSAPTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVP 22397
Query: 1015 AGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRV 1074
E T + + R ++ V + + + VD P P+ V
Sbjct: 22398 CLE---CNYKVTGLVEGLEYQFRTYA-LNAAGVSKASEASRPIMAQNPVDAPGRPE---V 22450
Query: 1075 TDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTM---EW----FTVLEHYRRTHCVVP 1127
TD V+L W P G +++ GY +++ + W +T++ T +
Sbjct: 22451 TDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALS 22510
Query: 1128 ELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPL 1187
E G+ Y FRV ++N G + + + PV Y PP + LD
Sbjct: 22511 E---GDTYEFRVLAKNAAGVISKGSESTGPVTCRDE---YAPPKAE-LDARLHGDLV--- 22560
Query: 1188 VNRSVIAGYTAMLCCAVRGSPKPKISWFKNG--LDLGEDARFRMFSKQGVLTLEIRKPCP 1245
++ AG +L AV G P+PKI W K LDL E + K+ T I+
Sbjct: 22561 ---TIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRA--TAVIKFCDR 22615
Query: 1246 FDGGIYVCRATNLQG 1260
D G Y N G
Sbjct: 22616 SDSGKYTLTVKNASG 22630
Score = 63.2 bits (152), Expect = 2e-09
Identities = 81/335 (24%), Positives = 134/335 (40%), Gaps = 41/335 (12%)
Query: 950 AGPG---APVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVT 1006
AGPG AP T+PV VQ++++ G V G P+P V
Sbjct: 1028 AGPGEPAAPYFITKPV-VQKLVE------------------GGSVVFGCQVGGNPKPHVY 1068
Query: 1007 WTKEGQPLAGE---EVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVV 1063
W K G PL +VS + L I +G Y + VR ++ E A+ L
Sbjct: 1069 WKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEE 1128
Query: 1064 DKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKK-TMEWFTVLEHYRRT 1122
+ + V + P+ VG T G+ + +K+ E + + +
Sbjct: 1129 ADYELLMKSQQEMLYQTQVTAFVQEPK-VGETAP-GFVYSEYEKEYEKEQALIRKKMAKD 1186
Query: 1123 HCVVPELIIGNGYYFRVFSQNMVGFSDRAA--TTKEPVFIPRPGITYEPPNYKALDFSEA 1180
VV + ++ F + ++ + TT E + + + A+D SE+
Sbjct: 1187 TVVVRTYVEDQEFHISSFEERLIKEIEYRIIKTTLEEL------LEEDGEEKMAVDISES 1240
Query: 1181 PS----FTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRM-FSKQGV 1235
+ F + N ++ G C + G P PKI+W+K+G + R++M F + G
Sbjct: 1241 EAVESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGR 1300
Query: 1236 LTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
+L I P D GIY A+N++G A C +L V
Sbjct: 1301 ASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYV 1335
Score = 62.4 bits (150), Expect = 3e-09
Identities = 65/275 (23%), Positives = 104/275 (37%), Gaps = 65/275 (23%)
Query: 1032 IRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQD 1091
++A +V G Y + ++N + P PP D+ V + + + WKPP
Sbjct: 8056 VKAVNKVGGGEY---IELKN----PVIAQDPKQPPDPPVDVEVHNPTAEAMTITWKPPLY 8108
Query: 1092 VGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELII-------GNGYYFRVFSQNM 1144
G +++ GY ++K K W EH +VP L G Y FRV ++N
Sbjct: 8109 DGGSKIMGYIIEKIAKGEERWKRCNEH------LVPILTYTAKGLEEGKEYQFRVRAENA 8162
Query: 1145 VGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAV 1204
G S+ + T P KA+D +AP + V G L ++
Sbjct: 8163 AGISEPSRAT---------------PPTKAVDPIDAPKVILR-TSLEVKRGDEIALDASI 8206
Query: 1205 RGSPKPKISWFKN-GLDLGEDARFRMF----------------------------SKQGV 1235
GSP P I+W K+ + + E+ + R SK+G
Sbjct: 8207 SGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGE 8266
Query: 1236 LTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
L +R D G+Y+ + N G A+ C + V
Sbjct: 8267 SQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSV 8301
Score = 60.5 bits (145), Expect = 1e-08
Identities = 55/197 (27%), Positives = 95/197 (48%), Gaps = 10/197 (5%)
Query: 451 EPPVLITRPLEDQLVMVGQRVEFECEV-SEEGAQVKWLKDGVELTREETFKYRFKKDGQR 509
E P + R ++ Q V G F V + + +W K+GV++ R + + + +D
Sbjct: 2030 EAPKIFER-IQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNV- 2087
Query: 510 HHLIINEAMLEDAGHY---ALCTSG-GQALAELIVQEKKLEVY-QSIADLMVGAKD-QAV 563
L+I + ED+ A+ +G + A L+VQ K+L + Q + D++ KD A
Sbjct: 2088 CELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMAT 2147
Query: 564 FKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFV-PEGFA 622
F+CE S+ V+ W K+G E+ + ++ +VH L+I + +D DYS V E
Sbjct: 2148 FECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDEN 2207
Query: 623 CNLSAKLHFMEVKIDFV 639
+AKL ++FV
Sbjct: 2208 VKTTAKLIVEGAVVEFV 2224
Score = 59.7 bits (143), Expect = 2e-08
Identities = 28/95 (29%), Positives = 46/95 (48%)
Query: 1176 DFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGV 1235
+ S+AP+F ++++ G + C + G P P+I WFKN L + + + + V
Sbjct: 26632 ELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNV 26691
Query: 1236 LTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
+LEIR D G Y +A N +G+ L V
Sbjct: 26692 YSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 26726
Score = 59.3 bits (142), Expect = 2e-08
Identities = 84/343 (24%), Positives = 125/343 (36%), Gaps = 68/343 (19%)
Query: 441 EKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEV-SEEGAQVKWLKDGVELTREETF 499
E S + F + IT + V GQ F V S+ A+VKW +GVEL +E+
Sbjct: 25864 EVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVEL--QESS 25921
Query: 500 KYRFKKDGQRHHLIINEAMLEDAGHY-ALCTS-GGQALAELIVQEKKLEVYQSIADLMVG 557
K + L I + +D+G Y A+CT+ G+A A L V
Sbjct: 25922 KIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEA--------------SDYATLDVT 25967
Query: 558 AKDQAVFKCEVSDENV-RGVWLKNGKELVPDSRIKVSHIGRVHKLTIDD--------VTP 608
D + + DE V R V+ EL VS + ++ +T
Sbjct: 25968 GGDYTTYASQRRDEEVPRSVF----PELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTE 26023
Query: 609 ADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRI---PDTIVVVAGN 665
E+ S+ A SA L ++ R KI RI P ++ V G
Sbjct: 26024 TRESLSSYEHSASAEMKSAALEEKSLEEKSTTR----KIKTTLAARILTKPRSMTVYEGE 26079
Query: 666 KLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRV 725
R G+P PTV W + K + T R
Sbjct: 26080 SARFSCDTDGEPVPTVTWLR-----------------------------KGQVLSTSARH 26110
Query: 726 RVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKV 768
+V TTK +S F + + DEG Y+V V+N G+ + T+ +
Sbjct: 26111 QVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTI 26153
Score = 57.0 bits (136), Expect = 1e-07
Identities = 69/305 (22%), Positives = 116/305 (38%), Gaps = 26/305 (8%)
Query: 976 PRHLRQTIQKKVGEPVNLLIPFQ--GKPRPQVTWTKEGQPLA-GEEVSIRNSPTDTILFI 1032
P + Q + + E N+L + G+P P++ W K P++ VSI S L I
Sbjct: 26637 PAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEI 26696
Query: 1033 RAARRVHSGTYQVTVRIENMEDKAT---LVLQVVDKPSPPQDLRVTDAWGLNVALEWKPP 1089
R A SG Y + + + AT +VL +V++PS LR + L + +
Sbjct: 26697 RNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQGSFSSQSV 26756
Query: 1090 Q-DVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFS 1148
Q E + + +M ++ + E + + S + +G S
Sbjct: 26757 QMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFV------EMSSSSFMGIS 26810
Query: 1149 DRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSP 1208
+ + + GI PP +AL PS + S+ G + CA G P
Sbjct: 26811 NMTQLESSTSKMLKAGIRGIPPKIEAL-----PS------DISIDEGKVLTVACAFTGEP 26859
Query: 1209 KPKISWFKNG--LDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCEC 1266
P+++W G + E RF + + + TL I DGG+Y N G
Sbjct: 26860 TPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATV 26919
Query: 1267 RLEVR 1271
+ +R
Sbjct: 26920 NIHIR 26924
Score = 54.7 bits (130), Expect = 6e-07
Identities = 27/94 (28%), Positives = 44/94 (46%)
Query: 1181 PSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEI 1240
P+ L N +VI G + L C + G P P ++W++ + F++ + G+ L I
Sbjct: 897 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMI 956
Query: 1241 RKPCPFDGGIYVCRATNLQGEARCECRLEVRVPQ 1274
R+ D G + C A N G C L V+V +
Sbjct: 957 REAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSE 990
Score = 54.7 bits (130), Expect = 6e-07
Identities = 28/94 (29%), Positives = 45/94 (47%)
Query: 1180 APSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLE 1239
AP + + V G+ A C ++ +P + WFK G ++ E + + S + + +LE
Sbjct: 4336 APVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLE 4395
Query: 1240 IRKPCPFDGGIYVCRATNLQGEARCECRLEVRVP 1273
I + D G Y C+A+N G C L V VP
Sbjct: 4396 ILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVP 4429
Score = 54.7 bits (130), Expect = 6e-07
Identities = 24/85 (28%), Positives = 44/85 (51%)
Query: 12 FSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREV 71
F KP+++E+ G A F + V+W+R + + +KY + +G + L V++
Sbjct: 6057 FISKPQNLEILEGEKAEFVCSISKESFPVQWKRDDKTLESGDKYDVIADGKKRVLVVKDA 6116
Query: 72 GPADQGSYAVIAGSSKVKFDLKVIE 96
D G+Y V+ G+++ L VIE
Sbjct: 6117 TLQDMGTYVVMVGAARAAAHLTVIE 6141
Score = 54.3 bits (129), Expect = 7e-07
Identities = 31/96 (32%), Positives = 42/96 (43%)
Query: 1179 EAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTL 1238
E P Q L +V +G A C + G P+PKISW+K L + + TL
Sbjct: 3191 EPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTL 3250
Query: 1239 EIRKPCPFDGGIYVCRATNLQGEARCECRLEVRVPQ 1274
+ + P D +Y C A N G A L V VP+
Sbjct: 3251 LLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPE 3286
Score = 54.3 bits (129), Expect = 7e-07
Identities = 111/523 (21%), Positives = 174/523 (33%), Gaps = 88/523 (16%)
Query: 316 PAEEDVWEILRQAPPSEYERIAFQYGVTDLRGMLKRLKGMRRD-------EKKSTAFQKK 368
PAEE + R++P E R V+ R + + + R D K + QK
Sbjct: 25799 PAEEYEDDTERRSPTPERTRPRSPSPVSSERSLSRFERSARFDIFSRYESMKAALKTQKT 25858
Query: 369 LEPAYQV------SKGHKIRLTVELADH------------------DAEVKWLKNGQEIQ 404
E Y+V + H R+T+ + H AEVKW NG E+Q
Sbjct: 25859 SERKYEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQ 25918
Query: 405 MSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCSTELFV--------------- 449
S SK + + TL I C D Y+ V K +
Sbjct: 25919 ES-SKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQ 25977
Query: 450 ---KEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKKD 506
+E P + L + E+ E + V+ +K + TRE Y
Sbjct: 25978 RRDEEVPRSVFPELTRTEAYAVSSFKKTSEM-EASSSVREVKSQMTETRESLSSYEHSAS 26036
Query: 507 GQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFKC 566
+ + E LE+ + A ++ + + + VY+ + A F C
Sbjct: 26037 AEMKSAALEEKSLEEKSTTRKIKT--TLAARILTKPRSMTVYEG---------ESARFSC 26085
Query: 567 EVSDENVRGV-WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNL 625
+ E V V WL+ G+ L +R +V+ I V +DE +YS V E
Sbjct: 26086 DTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQ 26145
Query: 626 SA-------KLHFMEVKIDFVPRQEPPKIHLDCPGRI--PDTIVVVAGNKLRLDVPISGD 676
A K E + PR + P+ + P + P + + + P
Sbjct: 26146 EAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETK 26205
Query: 677 PAPT-------VIWQKAITQGNKAPARP-------APDAPEDTGDSDEWVFDKKLLCETE 722
P PT V ITQ KA A ++ W D K L E
Sbjct: 26206 PTPTEKVQHLPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKE-N 26264
Query: 723 GRVRVETTKDRSI-FTVEGAEKEDEGVYTVTVKNPVGEDQVNL 764
G + + D + + + D+G Y + G + NL
Sbjct: 26265 GHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNL 26307
Score = 53.1 bits (126), Expect = 2e-06
Identities = 31/104 (29%), Positives = 46/104 (44%)
Query: 1167 YEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDAR 1226
YE + + AP T + + V G V+ P ++ W+ NG++L E ++
Sbjct: 25863 YEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSK 25922
Query: 1227 FRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
+ GVLTLEI D G Y TN +GEA L+V
Sbjct: 25923 IHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDV 25966
Score = 52.8 bits (125), Expect = 2e-06
Identities = 28/90 (31%), Positives = 42/90 (46%)
Query: 6 KKPVSAFSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHT 65
K+P F+K V G+ AV E E R KV+W + G++I S KY + +G
Sbjct: 5784 KEPPVEFTKPLEDQTVEEGATAVLECEVSRENAKVKWFKNGTEILKSKKYEIVADGRVRK 5843
Query: 66 LTVREVGPADQGSYAVIAGSSKVKFDLKVI 95
L + + P D +Y A K +L V+
Sbjct: 5844 LVIHDCTPEDIKTYTCDAKDFKTSCNLNVV 5873
Score = 52.4 bits (124), Expect = 3e-06
Identities = 52/164 (31%), Positives = 74/164 (45%), Gaps = 17/164 (10%)
Query: 378 GHKIRLTVELADH-DAEVKWLKNGQEIQMSGS--KYIFESIGAKRTLTISQCSLADDAAY 434
G +R V + H + V W K+GQ+I+ + KY FES LTI+ + DDA Y
Sbjct: 25207 GENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEY 25266
Query: 435 QCVV----GGEKCSTELFV--KEPPVLIT-RPLEDQLV-----MVGQRVEFECEVSE-EG 481
V G + C +L V PP T RP+ +L+ GQ V FE VS
Sbjct: 25267 TVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPP 25326
Query: 482 AQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHY 525
+KW KDG L+ + + + L I + + ED G+Y
Sbjct: 25327 PTLKWEKDGQPLSLGPNIEI-IHEGLDYYALHIRDTLPEDTGYY 25369
Score = 52.0 bits (123), Expect = 4e-06
Identities = 26/86 (30%), Positives = 45/86 (52%)
Query: 14 KKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGP 73
+ P+ + A G+ VF AE + V+V+W R + +K+ + +EG H L + ++ P
Sbjct: 6419 RPPQDILEAPGADVVFLAELNKDKVEVQWLRNNMVVVQGDKHQMMSEGKIHRLQICDIKP 6478
Query: 74 ADQGSYAVIAGSSKVKFDLKVIEAEK 99
DQG Y IA + + L++ A K
Sbjct: 6479 RDQGEYRFIAKDKEARAKLELAAAPK 6504
Score = 50.8 bits (120), Expect = 8e-06
Identities = 51/207 (24%), Positives = 78/207 (37%), Gaps = 17/207 (8%)
Query: 1055 KATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGY-TVQKADKKTMEWF 1113
K L + +P PP+ L VT+ + L W PP G ++ GY T + +++ + +
Sbjct: 12291 KPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRW 12350
Query: 1114 TVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYK 1173
T + VV L G Y FRV ++N VG S +PR Y+
Sbjct: 12351 TEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVS-----------LPREAEGV----YE 12395
Query: 1174 ALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQ 1233
A + P P ++ AG + V G P P W K ++ + +
Sbjct: 12396 AKEQLLPPKILMP-EQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKAD 12454
Query: 1234 GVLTLEIRKPCPFDGGIYVCRATNLQG 1260
L I+ D G Y A N G
Sbjct: 12455 SSSILIIKDVTRKDSGYYSLTAENSSG 12481
Score = 50.4 bits (119), Expect = 1e-05
Identities = 22/81 (27%), Positives = 39/81 (48%)
Query: 17 RSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQ 76
+ +E F + R V ++W + G ++ N+ + +H LT+++ G D+
Sbjct: 6244 KDIETMEKKSVTFWCKVNRLNVTLKWTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGFPDE 6303
Query: 77 GSYAVIAGSSKVKFDLKVIEA 97
G Y V AG K +L +IEA
Sbjct: 6304 GEYIVTAGQDKSVAELLIIEA 6324
Score = 50.1 bits (118), Expect = 1e-05
Identities = 53/164 (32%), Positives = 80/164 (48%), Gaps = 20/164 (12%)
Query: 393 EVKWLKNGQEIQMS---GSKYIFESIGAKRTLTISQCSLADDAAYQCVV---GGEKCST- 445
EV W ++GQ I S G + F AK LTI + A+ Y G+ ST
Sbjct: 36 EVSWFRDGQVISTSTLPGVQISFSDGRAK--LTIPAVTKANSGRYSLKATNGSGQATSTA 93
Query: 446 ELFVKE---PPVLITRPLEDQLVMVGQRVEFECEVSEEGAQV-KWLKDGVELTREETFKY 501
EL VK PP + R L+ V G +V + V+ V K+ +DG E+ + + +
Sbjct: 94 ELLVKAETAPPNFVQR-LQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEI--QSSLDF 150
Query: 502 RFKKDGQRHHLIINEAMLEDAGHYAL--CTSGGQA--LAELIVQ 541
+ ++G + L+I EA ED+G Y++ S G+A AEL+VQ
Sbjct: 151 QISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194
Score = 49.7 bits (117), Expect = 2e-05
Identities = 54/228 (23%), Positives = 83/228 (36%), Gaps = 35/228 (15%)
Query: 1058 LVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLE 1117
L + + P+ P+ L T+ + L+WK P+ G + + GY ++K ++ E
Sbjct: 8790 LAVDPLGPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDF----E 8845
Query: 1118 HYRRTHCVVPELIIGN-----GYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNY 1172
+ C ++ N Y FRV + N +G S+ + P N
Sbjct: 8846 RVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSL----------------PLNV 8889
Query: 1173 KALDFSEAPSFTQPLVNRS----VIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFR 1228
D P+ L R V AG + V G P PKI W KN + +
Sbjct: 8890 VIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDAL 8949
Query: 1229 MFSKQGV------LTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
+K+ V L I K D G Y A+N G +EV
Sbjct: 8950 QITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEV 8997
Score = 49.7 bits (117), Expect = 2e-05
Identities = 24/94 (25%), Positives = 40/94 (42%)
Query: 1178 SEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLT 1237
S P L + +V + A G P+P W K+G + + ++++ +G
Sbjct: 26352 SSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFF 26411
Query: 1238 LEIRKPCPFDGGIYVCRATNLQGEARCECRLEVR 1271
LEI K D G+Y C N G C+L ++
Sbjct: 26412 LEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIK 26445
Score = 48.5 bits (114), Expect = 4e-05
Identities = 24/81 (29%), Positives = 37/81 (45%)
Query: 14 KKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGP 73
KKP+ V + FE V V+W +I S+K+ L +E H L ++ + P
Sbjct: 2753 KKPKDVTALENATVAFEVSVSHDTVPVKWFHKSVEIKPSDKHRLVSERKVHKLMLQNISP 2812
Query: 74 ADQGSYAVIAGSSKVKFDLKV 94
+D G Y + G + K L V
Sbjct: 2813 SDAGEYTAVVGQLECKAKLFV 2833
Score = 48.1 bits (113), Expect = 5e-05
Identities = 30/96 (31%), Positives = 47/96 (48%), Gaps = 2/96 (2%)
Query: 1178 SEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDA--RFRMFSKQGV 1235
++AP+FTQPL + V+ G TA + G P P++SWF++G + ++ G
Sbjct: 3 TQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGR 62
Query: 1236 LTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVR 1271
L I + G Y +ATN G+A L V+
Sbjct: 63 AKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98
Score = 48.1 bits (113), Expect = 5e-05
Identities = 54/233 (23%), Positives = 91/233 (39%), Gaps = 50/233 (21%)
Query: 545 LEVYQSIADLMVGAKD----QAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHK 600
L+ + I D+++ + A+F+C VS W+K+G + + + G+ K
Sbjct: 4618 LKFVKEIKDIILTESEFVGSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIADGKDRK 4677
Query: 601 LTIDDVTPADEADYSFVPE--GFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDT 658
L I DV +D +Y+ V +AKL E+ + FV E +
Sbjct: 4678 LHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEELPVRFVKTLE-------------EE 4724
Query: 659 IVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLL 718
+ VV G L L ++ + V+W+K D K++
Sbjct: 4725 VTVVKGQPLYLSCELNKE--RDVVWRK----------------------------DGKIV 4754
Query: 719 CETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDV 771
E GR+ T+ A+ D G YTVTV+N + + VKV++V
Sbjct: 4755 VEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVEN-ANNLECSSCVKVVEV 4806
Score = 47.8 bits (112), Expect = 7e-05
Identities = 31/102 (30%), Positives = 44/102 (43%)
Query: 1169 PPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFR 1228
P + + P F + + N + G A L V G PKPKI WF NG+ L A ++
Sbjct: 3445 PTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYK 3504
Query: 1229 MFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
+L I D G Y C A+N G+ C L++
Sbjct: 3505 FVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKI 3546
Score = 47.8 bits (112), Expect = 7e-05
Identities = 26/93 (27%), Positives = 41/93 (44%), Gaps = 3/93 (3%)
Query: 1181 PSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDL---GEDARFRMFSKQGVLT 1237
P FT PL N++ G + P+P ++W+K+G + D ++ S +G+
Sbjct: 25193 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQ 25252
Query: 1238 LEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
L I D Y A N GE C+ +L V
Sbjct: 25253 LTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV 25285
Score = 47.0 bits (110), Expect = 1e-04
Identities = 27/91 (29%), Positives = 40/91 (43%), Gaps = 1/91 (1%)
Query: 1181 PSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMF-SKQGVLTLE 1239
P F + L G A+ V G P P ++WFK L + + + G T
Sbjct: 3575 PHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFI 3634
Query: 1240 IRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
+ P D G+Y+C+A N+ GE+ C L V
Sbjct: 3635 VNDPQREDSGLYICKAENMLGESTCAAELLV 3665
Score = 45.8 bits (107), Expect = 3e-04
Identities = 22/82 (26%), Positives = 35/82 (42%)
Query: 13 SKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVG 72
+K +++EV A FE E V W + G +I S K+ + +G H L +
Sbjct: 2839 TKTMKNIEVPETKTASFECEVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTS 2898
Query: 73 PADQGSYAVIAGSSKVKFDLKV 94
D Y + G+ +V L V
Sbjct: 2899 TEDSAEYTFVCGNDQVSATLTV 2920
Score = 45.1 bits (105), Expect = 4e-04
Identities = 27/80 (33%), Positives = 37/80 (46%)
Query: 17 RSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQ 76
+ V V AG A F+ E + V W G + S+K +EG HTLT+R+V D
Sbjct: 5706 KDVTVTAGETATFDCELSYEDIPVEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLEDA 5765
Query: 77 GSYAVIAGSSKVKFDLKVIE 96
G + A K +L V E
Sbjct: 5766 GEVQLTAKDFKTHANLFVKE 5785
Score = 45.1 bits (105), Expect = 4e-04
Identities = 29/91 (31%), Positives = 44/91 (48%), Gaps = 5/91 (5%)
Query: 1183 FTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRK 1242
FT+PL +++V G TA+L C V K+ WFKNG ++ + ++ + + V L I
Sbjct: 5790 FTKPLEDQTVEEGATAVLECEV-SRENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHD 5848
Query: 1243 PCPFDGGIYVCRATNLQGEARCECRLEVRVP 1273
P D Y C A + + C L V P
Sbjct: 5849 CTPEDIKTYTCDAKDF----KTSCNLNVVPP 5875
Score = 44.7 bits (104), Expect = 6e-04
Identities = 33/108 (30%), Positives = 43/108 (39%), Gaps = 6/108 (5%)
Query: 1165 ITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNG--LDLG 1222
+T PP D + P F + L N G + V G P P + W K+G L LG
Sbjct: 25285 VTLHPP---PTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLG 25341
Query: 1223 EDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
+ + L IR P D G Y ATN G C+ L+V
Sbjct: 25342 PNIEI-IHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQV 25388
Score = 44.7 bits (104), Expect = 6e-04
Identities = 48/223 (21%), Positives = 85/223 (38%), Gaps = 8/223 (3%)
Query: 558 AKDQAVFKCEVSDENVRG---VWLKNGKELVPDSRIKVSHIGR-VHKLTIDDVTPADEAD 613
+K+ A C V +R W K+GK+L + + + ++L I+++T +D+ +
Sbjct: 26232 SKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGE 26291
Query: 614 YSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPI 673
Y G L FM + + + V + + PI
Sbjct: 26292 YVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPI 26351
Query: 674 SGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDR 733
S P V + T + + A+ A A + + W D K + + G+ ++ K
Sbjct: 26352 SSKPV-IVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQG-GKYKLSEDKGG 26409
Query: 734 SIFTVEGAEKEDEGVYTVTVKNPVG--EDQVNLTVKVIDVPDA 774
+ + D G+YT TVKN G LT+K I +A
Sbjct: 26410 FFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEA 26452
Score = 44.3 bits (103), Expect = 8e-04
Identities = 26/91 (28%), Positives = 43/91 (47%)
Query: 1181 PSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEI 1240
P+F Q L + +V G L V G P P + ++++G ++ F++ + + +L I
Sbjct: 104 PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLI 163
Query: 1241 RKPCPFDGGIYVCRATNLQGEARCECRLEVR 1271
+ P D G Y ATN G A L V+
Sbjct: 164 AEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194
Score = 44.3 bits (103), Expect = 8e-04
Identities = 29/108 (26%), Positives = 49/108 (45%), Gaps = 16/108 (14%)
Query: 10 SAFSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVR 69
+ F+K ++EV+ E + G +V W +G +I + +Y + TEG + L ++
Sbjct: 5966 AVFTKNLANIEVSETDTIKLVCEVSKPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQ 6025
Query: 70 EVGPADQGSYAVIAGSS----KVKF------------DLKVIEAEKAE 101
D G+Y SS KVK +L+++E EKAE
Sbjct: 6026 NAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLEILEGEKAE 6073
Score = 43.5 bits (101), Expect = 0.001
Identities = 23/76 (30%), Positives = 35/76 (46%)
Query: 28 VFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYAVIAGSSK 87
VFE E +G+ V W +I S+KY + G + LTV + D+G Y AG +
Sbjct: 2505 VFEVELSHSGIDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTFYAGENM 2564
Query: 88 VKFDLKVIEAEKAEPM 103
L V ++P+
Sbjct: 2565 TSGKLTVAGGAISKPL 2580
Score = 43.1 bits (100), Expect = 0.002
Identities = 45/174 (25%), Positives = 72/174 (41%), Gaps = 10/174 (5%)
Query: 449 VKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKKDGQ 508
+KE +I PL D + G V ++ +V W + + +E FK +D
Sbjct: 4238 IKEDGPMIHTPLVDTVSEEGDIVHLTTSITN-AKEVNWYFENKLVPSDEKFKCL--QDQN 4294
Query: 509 RHHLIINEAMLED-AGHY---ALCTSGGQALAELIVQEKKLE--VYQSIADLMVGAKDQA 562
+ L+I++ ED G Y AL SG A + + K+ + + I L V A
Sbjct: 4295 TYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLA 4354
Query: 563 VFKCEV-SDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYS 615
F CE+ S NVR W K G+E+ + + + L I D +Y+
Sbjct: 4355 KFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYT 4408
Score = 42.0 bits (97), Expect = 0.004
Identities = 33/111 (29%), Positives = 51/111 (45%), Gaps = 14/111 (12%)
Query: 453 PVLITRPLEDQLVMVGQRVEFECEVS-EEGAQVKWLKDGVELTREETFKYRFKKDGQRHH 511
P IT+P+ +LV G V F C+V V W K GV LT +K + K
Sbjct: 1036 PYFITKPVVQKLVEGGS-VVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECK 1094
Query: 512 LIINEAMLEDAGHYALC-------TSGGQALA-----ELIVQEKKLEVYQS 550
L+I+ +DAG Y + TS +L EL+++ ++ +YQ+
Sbjct: 1095 LVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLMKSQQEMLYQT 1145
Score = 41.6 bits (96), Expect = 0.005
Identities = 21/86 (24%), Positives = 38/86 (44%)
Query: 9 VSAFSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTV 68
V F K+ + +EV E ++ +W ++ ++ KY + + R LTV
Sbjct: 2220 VVEFVKELQDIEVPESYSGELECIVSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTV 2279
Query: 69 REVGPADQGSYAVIAGSSKVKFDLKV 94
++V DQG Y+ + K LK+
Sbjct: 2280 KDVTKEDQGEYSFVIDGKKTTCKLKM 2305
Score = 41.6 bits (96), Expect = 0.005
Identities = 26/94 (27%), Positives = 38/94 (40%), Gaps = 1/94 (1%)
Query: 1181 PSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEI 1240
P+ PL + G A C V G+ K+SW+ + FRM + LEI
Sbjct: 3299 PAIITPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEI 3357
Query: 1241 RKPCPFDGGIYVCRATNLQGEARCECRLEVRVPQ 1274
+ P D G Y A+N G+ L + P+
Sbjct: 3358 AEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPE 3391
Score = 41.2 bits (95), Expect = 0.006
Identities = 23/105 (21%), Positives = 46/105 (43%), Gaps = 16/105 (15%)
Query: 12 FSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREV 71
F K + ++V A+FE E + V+W + ++ +++ + E H L +
Sbjct: 3014 FRKHIKDIKVLEKKRAMFECEVSEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPST 3073
Query: 72 GPADQGSYAVIAGSS----------------KVKFDLKVIEAEKA 100
+D G Y V+AG + +K +++VIE ++A
Sbjct: 3074 RMSDAGKYTVVAGGNVSTAKLFVEGRDVRIRSIKKEVQVIEKQRA 3118
Score = 41.2 bits (95), Expect = 0.006
Identities = 23/91 (25%), Positives = 41/91 (45%)
Query: 8 PVSAFSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLT 67
P F + ++V A FE E R KV+W + G++I KY + ++G L
Sbjct: 5875 PHVEFLRPLTDLQVREKEMARFECELSRENAKVKWFKDGAEIKKGKKYDIISKGAVRILV 5934
Query: 68 VREVGPADQGSYAVIAGSSKVKFDLKVIEAE 98
+ + D+ Y+ +++ L V+E E
Sbjct: 5935 INKCLLDDEAEYSCEVRTARTSGMLTVLEEE 5965
Score = 40.8 bits (94), Expect = 0.008
Identities = 38/167 (22%), Positives = 69/167 (41%), Gaps = 8/167 (4%)
Query: 457 TRPLEDQLVMVGQRVEFECEVSE-EGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIIN 515
T+PL+ +V+ G FE +S +V W +DG ++ + R L I
Sbjct: 9 TQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIP 68
Query: 516 EAMLEDAGHYALCTSGGQ----ALAELIVQEKKL--EVYQSIADLMVGAKDQAVFKCEVS 569
++G Y+L + G + AEL+V+ + Q + + V Q + V+
Sbjct: 69 AVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVT 128
Query: 570 DENVRGV-WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYS 615
V + ++G E+ ++S G ++ L I + P D YS
Sbjct: 129 GIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYS 175
Score = 40.8 bits (94), Expect = 0.008
Identities = 21/70 (30%), Positives = 36/70 (51%), Gaps = 1/70 (1%)
Query: 27 AVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYA-VIAGS 85
A FE ET VKV+W + G ++ +KY + ++ H L++ + +D Y+ V+
Sbjct: 2146 ATFECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVED 2205
Query: 86 SKVKFDLKVI 95
VK K+I
Sbjct: 2206 ENVKTTAKLI 2215
Score = 40.8 bits (94), Expect = 0.008
Identities = 29/105 (27%), Positives = 44/105 (41%), Gaps = 9/105 (8%)
Query: 27 AVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYA--VIAG 84
AVF + R V+W R G +I KY +G+ H L +++ D+ YA V
Sbjct: 6343 AVFSCQLSREKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDCRLDDECEYACGVEDR 6402
Query: 85 SSKVKFDLKVIEAEKAEPMLAPAPAPAEATGAPGEAPAPAAELGE 129
S+ + ++ I E P P + APG AEL +
Sbjct: 6403 KSRARLFVEEIPVEIIRP-------PQDILEAPGADVVFLAELNK 6440
Score = 40.8 bits (94), Expect = 0.008
Identities = 24/80 (30%), Positives = 38/80 (47%), Gaps = 1/80 (1%)
Query: 40 VRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYAVIAGSSKVKFDLKVIEAEK 99
++W R G ++ S KY ++++G HTLTV D+G Y IA + + + +
Sbjct: 24067 IKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQ 24126
Query: 100 AEPMLAPA-PAPAEATGAPG 118
A P P P + GA G
Sbjct: 24127 ATPQFHPGYPLKEKYYGAVG 24146
Score = 40.8 bits (94), Expect = 0.008
Identities = 69/326 (21%), Positives = 130/326 (39%), Gaps = 64/326 (19%)
Query: 478 SEEGAQVKWLKDGVELTREE---TFKYR------FKKDGQRHHLIINEAMLEDAGHYALC 528
+ E Q WLK +E + T K+R KKD +++++ A + G A+
Sbjct: 24999 ASEALQHPWLKQKIERVSTKVIRTLKHRRYYHTLIKKD---LNMVVSAARISCGG--AIR 25053
Query: 529 TSGGQALAELIVQEKKL-----EVYQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKE 583
+ G ++A++ V ++ ++ ++ + G + V K E D++ + W ++
Sbjct: 25054 SQKGVSVAKVKVASIEIGPVSGQIMHAVGE--EGGHVKYVCKIENYDQSTQVTWYFGVRQ 25111
Query: 584 LVPDSRIKVSHIGRVHKLTIDDVTPADEADY--SFVPEGFACNLSAKLHFMEVK--IDFV 639
L + ++++ V L + D+T D+ Y V + + A+L V+ D+
Sbjct: 25112 LENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFVKGVREVYDYY 25171
Query: 640 PRQEPPKIH--------LDCPGRIPDTI---VVVAGNKLRLDVPISGDPAPTVIWQKAIT 688
R+ KI L+ P + G +R V I+ P P V W K+
Sbjct: 25172 CRRTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKS-- 25229
Query: 689 QGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGV 748
G K +P + + T +SD+ ++ T+ +D+
Sbjct: 25230 -GQKI--KPGDNDKKYTFESDKGLYQ---------------------LTINSVTTDDDAE 25265
Query: 749 YTVTVKNPVGED--QVNLTVKVIDVP 772
YTV +N GED + LTV + P
Sbjct: 25266 YTVVARNKYGEDSCKAKLTVTLHPPP 25291
Score = 40.4 bits (93), Expect = 0.011
Identities = 18/57 (31%), Positives = 30/57 (52%)
Query: 38 VKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYAVIAGSSKVKFDLKV 94
V V+W + G +I S KY + +G R L +++ D+G Y G+ K K ++ V
Sbjct: 5193 VPVKWFKDGEEIVPSPKYSIKADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTV 5249
Score = 40.4 bits (93), Expect = 0.011
Identities = 17/61 (27%), Positives = 31/61 (50%)
Query: 19 VEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGS 78
V+V A FE E R RW +G +I+ +++ L +GT+H++ ++ D+
Sbjct: 5352 VKVFEKDEAKFECEVSREPKTFRWLKGTQEITGDDRFELIKDGTKHSMVIKSAAFEDEAK 5411
Query: 79 Y 79
Y
Sbjct: 5412 Y 5412
Score = 39.7 bits (91), Expect = 0.019
Identities = 46/199 (23%), Positives = 87/199 (43%), Gaps = 20/199 (10%)
Query: 453 PVLITRPLEDQLVMVGQRVEFECEV-SEEGAQVKWLKDGVELTREETFKYRFKKDGQRHH 511
PV + +P+ + + GQ F+ +V + W DG ++ + T K K+DG +
Sbjct: 1411 PVFVLKPVSFKC-LEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQ-S 1468
Query: 512 LIINEAMLEDAGHYALCT---SGGQALAELI-VQEKKLEVYQSIADLM--VGAKDQAVFK 565
LII A D+G + + +G +++ ++ V+ + +V + + V K+ + +
Sbjct: 1469 LIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLE 1528
Query: 566 CEV---SDENVRGVWLKNGKELVPDS--RIKVSHIGRVHKLTIDDVTPADEADYSFVPEG 620
+V + N VWLKN +VP +I++ L ID D A Y+
Sbjct: 1529 MKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAIN 1588
Query: 621 FA------CNLSAKLHFME 633
A C ++ ++ F E
Sbjct: 1589 KAGRDTTRCKVNVEVEFAE 1607
Score = 39.3 bits (90), Expect = 0.024
Identities = 29/94 (30%), Positives = 37/94 (39%), Gaps = 1/94 (1%)
Query: 11 AFSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVRE 70
A SK VA AVFE E K W R G + +N ++G + L +
Sbjct: 2575 AISKPLTDQTVAESQEAVFECEVANPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAA 2634
Query: 71 VGPADQGSYAVIAGSSKVKFDLKVIEAEKAEPML 104
D G Y +SK LKV EA K + L
Sbjct: 2635 TKLDDIGEYTYKVATSKTSAKLKV-EAVKIKKTL 2667
Score = 39.3 bits (90), Expect = 0.024
Identities = 22/88 (25%), Positives = 41/88 (46%), Gaps = 16/88 (18%)
Query: 29 FEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYAVIAGSS-- 86
FE G+ +W + G +I +++K + T+ H+L +R V D Y +AG +
Sbjct: 2942 FEVTVNYEGISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKATS 3001
Query: 87 ---------KVKF-----DLKVIEAEKA 100
++F D+KV+E ++A
Sbjct: 3002 TATLYVEARHIEFRKHIKDIKVLEKKRA 3029
Score = 38.5 bits (88), Expect = 0.041
Identities = 22/81 (27%), Positives = 35/81 (43%)
Query: 1191 SVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGI 1250
+V G +A C G P P ++W + G L AR ++ + + T EI D G
Sbjct: 26074 TVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGN 26133
Query: 1251 YVCRATNLQGEARCECRLEVR 1271
Y N +G+ E L ++
Sbjct: 26134 YSVVVENSEGKQEAEFTLTIQ 26154
Score = 37.7 bits (86), Expect = 0.071
Identities = 30/109 (27%), Positives = 43/109 (39%), Gaps = 1/109 (0%)
Query: 1163 PGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLG 1222
PG E + L+ P F V+ + G TA V G P P+ WF +G +
Sbjct: 1393 PGRRLEETDESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIV 1452
Query: 1223 EDARFRMFSKQ-GVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
D ++ K+ G +L I P D G + A N G + L V
Sbjct: 1453 NDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTV 1501
Score = 37.0 bits (84), Expect = 0.12
Identities = 44/219 (20%), Positives = 72/219 (32%), Gaps = 44/219 (20%)
Query: 577 WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEG----FACNLSAKLH-- 630
W NG L P + K G H L I DE +Y+ + C+ K++
Sbjct: 3490 WFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSK 3549
Query: 631 ---FMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVA---GNKLRLDVPISGDPAPTVIWQ 684
+ + + + K+ CP + + G + + G+PAPTV W
Sbjct: 3550 GEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWF 3609
Query: 685 KAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKE 744
K + K LC + + F V ++E
Sbjct: 3610 K----------------------------ENKQLCTSVYYTIIHNPNGSGTFIVNDPQRE 3641
Query: 745 DEGVYTVTVKNPVGEDQVNLTVKVI----DVPDAPAAPK 779
D G+Y +N +GE + V+ D+ D P K
Sbjct: 3642 DSGLYICKAENMLGESTCAAELLVLLEDTDMTDTPCKAK 3680
Score = 36.6 bits (83), Expect = 0.16
Identities = 20/71 (28%), Positives = 33/71 (46%), Gaps = 3/71 (4%)
Query: 456 ITRPLEDQLVMVGQRVEFECE-VSEEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLII 514
I + ++D +G+ + C+ V +KW + G EL + KY+ DG+ H L +
Sbjct: 24038 IRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSR--KYKMSSDGRTHTLTV 24095
Query: 515 NEAMLEDAGHY 525
ED G Y
Sbjct: 24096 MTEEQEDEGVY 24106
Score = 36.6 bits (83), Expect = 0.16
Identities = 27/92 (29%), Positives = 42/92 (45%), Gaps = 5/92 (5%)
Query: 1175 LDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSP--KPKISWFKNGLDLGEDARFRM-FS 1231
L S P TQ L ++ + A L C V S +++W+K+G L E+ F+ +S
Sbjct: 26215 LPVSAPPKITQFL--KAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYS 26272
Query: 1232 KQGVLTLEIRKPCPFDGGIYVCRATNLQGEAR 1263
G L+I D G YVC + G ++
Sbjct: 26273 ADGTYELKINNLTESDQGEYVCEISGEGGTSK 26304
Score = 36.2 bits (82), Expect = 0.21
Identities = 20/79 (25%), Positives = 34/79 (43%), Gaps = 1/79 (1%)
Query: 17 RSVEVAAGSPAVFEAETERAGV-KVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPAD 75
+ V V G+ AV E + V V+W I ++ +GT+ L + +D
Sbjct: 2406 KDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHASD 2465
Query: 76 QGSYAVIAGSSKVKFDLKV 94
+G Y +I G + +L V
Sbjct: 2466 EGPYKLIVGRVETNCNLSV 2484
Score = 36.2 bits (82), Expect = 0.21
Identities = 55/274 (20%), Positives = 91/274 (33%), Gaps = 66/274 (24%)
Query: 17 RSVEVAAGSPAVFEAETERAGVKVRWQRGGSDIS--ASNKYGLATEGTRHTLTVREVGPA 74
+ V+V AV E E V W + G +I+ ++ E H + + E +
Sbjct: 3108 KEVQVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQS 3167
Query: 75 DQGSYAVIAGSSKVKFDLKVIEAE------KAEPMLAPAPAPAEATGAPGEAPAPAAE-- 126
D G Y +AG ++ L V E + +P+ + PA P P
Sbjct: 3168 DAGEYTFVAGRNRSSVTLYVNAPEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWY 3227
Query: 127 ------------------------LGESAPSPKG---------------SSSAALNGPTP 147
L E+ P S+S ++ P
Sbjct: 3228 KEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEV 3287
Query: 148 GAPDDPIGLF---VMRP-QDGEVTVGGSITFSARVAGASLLKPPVVKWFKGKWVDLSSKV 203
+PD + ++ ++ P QD + G F RV+G L V W+ S+
Sbjct: 3288 VSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDL----KVSWYSKDKKIKPSRF 3343
Query: 204 GQHLQLHDSYDRASKVYLFELHITDAQPAFTGSY 237
+ Q D+Y +L I +A P G+Y
Sbjct: 3344 FRMTQFEDTY---------QLEIAEAYPEDEGTY 3368
Score = 35.8 bits (81), Expect = 0.27
Identities = 19/72 (26%), Positives = 35/72 (48%), Gaps = 1/72 (1%)
Query: 14 KKPRSVEVAAGSPAVFEAETERAGVK-VRWQRGGSDISASNKYGLATEGTRHTLTVREVG 72
K +++ V AVF E VK V+W + G + ++ KY ++ +GT ++L ++
Sbjct: 2665 KTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYSLRIKNCA 2724
Query: 73 PADQGSYAVIAG 84
D+ Y G
Sbjct: 2725 IVDESVYGFRLG 2736
Score = 35.8 bits (81), Expect = 0.27
Identities = 23/78 (29%), Positives = 35/78 (44%)
Query: 19 VEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGS 78
VEV G A FE E V +W+ G ++AS + +G +H L + G
Sbjct: 5263 VEVFVGETAHFEIELSEPDVHGQWKLKGQPLTASPDCEIIEDGKKHILILHNCQLGMTGE 5322
Query: 79 YAVIAGSSKVKFDLKVIE 96
+ A ++K +LKV E
Sbjct: 5323 VSFQAANAKSAANLKVKE 5340
Score = 35.8 bits (81), Expect = 0.27
Identities = 18/78 (23%), Positives = 36/78 (46%), Gaps = 2/78 (2%)
Query: 28 VFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYAVIAGSSK 87
+ + E +A V+W + G +I S + +G + L +++ +D G Y G+ K
Sbjct: 5539 ILQCEISKADAPVKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTCDCGTDK 5598
Query: 88 V--KFDLKVIEAEKAEPM 103
K D++ E + P+
Sbjct: 5599 TSGKLDIEDREIKLVRPL 5616
Score = 35.8 bits (81), Expect = 0.27
Identities = 27/118 (22%), Positives = 50/118 (42%), Gaps = 19/118 (16%)
Query: 577 WLKNGKELVP---DSRIKVSHIGRVHKLTIDDVTPADEADYSFVP------EGFACNLSA 627
W K+G+++ P D + +++LTI+ VT D+A+Y+ V + L+
Sbjct: 25226 WYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV 25285
Query: 628 KLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQK 685
LH P + + +C G + ++ +SG P PT+ W+K
Sbjct: 25286 TLHPPPTDSTLRPMFKRLLANAECQ----------EGQSVCFEIRVSGIPPPTLKWEK 25333
Score = 35.4 bits (80), Expect = 0.35
Identities = 16/47 (34%), Positives = 30/47 (63%)
Query: 40 VRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYAVIAGSS 86
V++ R G++I +S + ++ EG ++L + E P D G+Y+V A +S
Sbjct: 135 VKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNS 181
Score = 35.4 bits (80), Expect = 0.35
Identities = 45/203 (22%), Positives = 72/203 (35%), Gaps = 60/203 (29%)
Query: 40 VRWQRGGSDISASN---KYGLATEGTRHTLTVREVGPADQGSYAVIAGSSKVKFDLKVIE 96
V W + G I + KY ++ + LT+ V D Y V+A + + +
Sbjct: 25224 VTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGE------D 25277
Query: 97 AEKAEPMLAPAPAPAEATGAPGEAPAPAAELGESAPSPKGSSSAALNGPTPGAPDDPIGL 156
+ KA+ + P P ++T P +
Sbjct: 25278 SCKAKLTVTLHPPPTDSTLRP--------------------------------------M 25299
Query: 157 FVMRPQDGEVTVGGSITFSARVAGASLLKPPVVKWFK-GKWVDLSSKVGQHLQLHDSYDR 215
F + E G S+ F RV+G + PP +KW K G+ + L + +H+ D
Sbjct: 25300 FKRLLANAECQEGQSVCFEIRVSG---IPPPTLKWEKDGQPLSLGPNIEI---IHEGLD- 25352
Query: 216 ASKVYLFELHITDAQPAFTGSYR 238
+ LHI D P TG YR
Sbjct: 25353 -----YYALHIRDTLPEDTGYYR 25370
Score = 35.0 bits (79), Expect = 0.46
Identities = 19/65 (29%), Positives = 28/65 (43%)
Query: 17 RSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQ 76
+ V VF E G K +W R I S+KY + + +TL +R+ DQ
Sbjct: 6150 KDTRVKEQQEVVFNCEVNTEGAKAKWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLDDQ 6209
Query: 77 GSYAV 81
+Y V
Sbjct: 6210 ANYNV 6214
Score = 34.7 bits (78), Expect = 0.60
Identities = 19/48 (39%), Positives = 25/48 (52%), Gaps = 2/48 (4%)
Query: 483 QVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTS 530
+++W +GV LT +K+ F DG H LII LED G Y S
Sbjct: 3487 KIQWFFNGVLLTPSADYKFVF--DGDDHSLIILFTKLEDEGEYTCMAS 3532
Score = 34.3 bits (77), Expect = 0.78
Identities = 20/85 (23%), Positives = 36/85 (42%), Gaps = 9/85 (10%)
Query: 5 GKKPVSAFSKKPRSVEVAAG--SPAVFEAETERAGVKVR-------WQRGGSDISASNKY 55
GKK KPR + + G V E + + VKV W + G ++ S++
Sbjct: 2296 GKKTTCKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRV 2355
Query: 56 GLATEGTRHTLTVREVGPADQGSYA 80
+ + H L + ++ D G+Y+
Sbjct: 2356 HIVIDKQSHMLLIEDMTKEDAGNYS 2380
Score = 34.3 bits (77), Expect = 0.78
Identities = 24/87 (27%), Positives = 42/87 (48%), Gaps = 4/87 (4%)
Query: 1179 EAPS-FTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLT 1237
EAP+ F + L +++V A+ C + K + W++NG ++ E +++ F K G +
Sbjct: 6323 EAPTEFVEHLEDQTVTEFDDAVFSCQL-SREKANVKWYRNGREIKEGKKYK-FEKDGSIH 6380
Query: 1238 LEIRKPCPFDGGI-YVCRATNLQGEAR 1263
I K C D Y C + + AR
Sbjct: 6381 RLIIKDCRLDDECEYACGVEDRKSRAR 6407
Score = 34.3 bits (77), Expect = 0.78
Identities = 20/65 (30%), Positives = 33/65 (50%), Gaps = 5/65 (7%)
Query: 393 EVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCV----VGGEKCSTELF 448
++KW + G+E+ S KY S G TLT+ D+ Y C+ VG + S++L
Sbjct: 24066 DIKWYRFGKELIQS-RKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLL 24124
Query: 449 VKEPP 453
++ P
Sbjct: 24125 LQATP 24129
Score = 33.9 bits (76), Expect = 1.0
Identities = 16/63 (25%), Positives = 27/63 (42%)
Query: 24 GSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYAVIA 83
G PA F+ +KV W I S + + + L + E P D+G+Y +A
Sbjct: 3313 GQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVA 3372
Query: 84 GSS 86
++
Sbjct: 3373 SNA 3375
Score = 33.9 bits (76), Expect = 1.0
Identities = 17/59 (28%), Positives = 27/59 (45%)
Query: 24 GSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYAVI 82
GS A+FE + W + GS+I S K+ +G L + +V +D G Y +
Sbjct: 4636 GSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYTCV 4694
Score = 33.5 bits (75), Expect = 1.3
Identities = 25/125 (20%), Positives = 50/125 (40%), Gaps = 7/125 (5%)
Query: 16 PRSVEVAAGSPAVFEAETE-RAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPA 74
P + + AG EA + +W++G ++ S+ + + L +++V
Sbjct: 12408 PEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRK 12467
Query: 75 DQGSYAVIAGSSKVKFDLKVIEAEKAEPMLAPAPAPAEATGAPGEAPAPAAELGESAPSP 134
D G Y++ A +S + +K + ++ AP P + + A A L P
Sbjct: 12468 DSGYYSLTAENS------SGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSLSWHIPLE 12521
Query: 135 KGSSS 139
G S+
Sbjct: 12522 DGGSN 12526
Score = 33.1 bits (74), Expect = 1.7
Identities = 53/201 (26%), Positives = 74/201 (36%), Gaps = 44/201 (21%)
Query: 87 KVKFDLKVIEAEKAEPMLAP--APAPAEATGAPGEAPAPAAELGE----------SAPSP 134
K + ++K I+ EP P AP G EA AP E + PSP
Sbjct: 4527 KPEAEVKTIKPPPVEPEPTPIAAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPSP 4586
Query: 135 KGSSSAALNGPTPGA--PDD----------PIGLFVMRPQDGEVT----VGGSITFSARV 178
+ L + G PD+ P+ FV +D +T VG S F V
Sbjct: 4587 IEAERRKLRPGSGGEKPPDEAPFTYQLKAVPLK-FVKEIKDIILTESEFVGSSAIFECLV 4645
Query: 179 AGASLLKPPVVKWFK-GKWVDLSSKVGQHLQLHDSYDRASKVYLFELHITDAQPAFTGSY 237
+ ++ + W K G + S K H + D DR +LHI D Q + G Y
Sbjct: 4646 SPSTA----ITTWMKDGSNIRESPK---HRFIADGKDR-------KLHIIDVQLSDAGEY 4691
Query: 238 RCEVSTKDKFDCSNFNLTVHE 258
C + +K S L V E
Sbjct: 4692 TCVLRLGNKEKTSTAKLVVEE 4712
Score = 33.1 bits (74), Expect = 1.7
Identities = 16/72 (22%), Positives = 31/72 (43%)
Query: 27 AVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYAVIAGSS 86
AVF E ++V+W + + + + EG H++T +++ D V A
Sbjct: 5449 AVFTVELSHDNIRVKWFKNDQRLHTTRSVSMQDEGKTHSITFKDLSIDDTSQIRVEAMGM 5508
Query: 87 KVKFDLKVIEAE 98
+ L V+E +
Sbjct: 5509 SSEAKLTVLEGD 5520
Score = 33.1 bits (74), Expect = 1.7
Identities = 21/84 (25%), Positives = 38/84 (45%), Gaps = 5/84 (5%)
Query: 19 VEVAAGSPAVFEAETE-RAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQG 77
V + AGS V +A + K+ W +G ++ K L G R T ++ +D G
Sbjct: 22560 VTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSG 22619
Query: 78 SYAV----IAGSSKVKFDLKVIEA 97
Y + +G+ V +KV+++
Sbjct: 22620 KYTLTVKNASGTKAVSVMVKVLDS 22643
Score = 32.7 bits (73), Expect = 2.3
Identities = 21/72 (29%), Positives = 35/72 (48%), Gaps = 2/72 (2%)
Query: 460 LEDQLVMVGQRVEFECEVSEEGA-QVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAM 518
+++ ++ G V F C++S ++ W KDG + E ++ F +DG R L I +
Sbjct: 1251 IKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDG-RASLRIPVVL 1309
Query: 519 LEDAGHYALCTS 530
ED G Y S
Sbjct: 1310 PEDEGIYTAFAS 1321
Score = 32.3 bits (72), Expect = 3.0
Identities = 43/171 (25%), Positives = 67/171 (39%), Gaps = 22/171 (12%)
Query: 948 NMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQT--IQKKVGEPVNLLIPFQGKPRPQV 1005
N G G T TE + + + P L++ I+ G P G+P P V
Sbjct: 3547 NSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTV 3606
Query: 1006 TWTKEGQPL-AGEEVSIRNSPTDTILFI-RAARRVHSGTYQVTVRIENMEDKAT------ 1057
TW KE + L +I ++P + FI +R SG Y + ENM ++T
Sbjct: 3607 TWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLY--ICKAENMLGESTCAAELL 3664
Query: 1058 LVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKK 1108
++L+ D P + T + P+D T L G V+ D +
Sbjct: 3665 VLLEDTDMTDTPCKAKSTP----------EAPEDFPQTPLKGPAVEALDSE 3705
Score = 32.3 bits (72), Expect = 3.0
Identities = 22/83 (26%), Positives = 34/83 (40%), Gaps = 1/83 (1%)
Query: 12 FSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREV 71
F+ + V V A FE R V W +G I +S+K+ + +G +H L + +
Sbjct: 4991 FAVPLKDVTVPERRQARFECVLTREA-NVIWSKGPDIIKSSDKFDIIADGKKHILVINDS 5049
Query: 72 GPADQGSYAVIAGSSKVKFDLKV 94
D+G Y K L V
Sbjct: 5050 QFDDEGVYTAEVEGKKTSARLFV 5072
Score = 32.3 bits (72), Expect = 3.0
Identities = 24/67 (35%), Positives = 30/67 (44%), Gaps = 5/67 (7%)
Query: 467 VGQRVEFECEVSEEG---AQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAG 523
V R + + +V +G A V W KDG L +ET + L I EA ED G
Sbjct: 18909 VKAREQLKIDVPFKGRPQATVNWRKDGQTL--KETTRVNVSSSKTVTSLSIKEASKEDVG 18966
Query: 524 HYALCTS 530
Y LC S
Sbjct: 18967 TYELCVS 18973
Score = 32.0 bits (71), Expect = 3.9
Identities = 21/81 (25%), Positives = 35/81 (43%), Gaps = 1/81 (1%)
Query: 6 KKPVSAFSKKPRSVEVAAGSPAVFEAETERA-GVKVRWQRGGSDISASNKYGLATEGTRH 64
K+ +K +EVA G A F E + A V+ +W + G +I S+K + +
Sbjct: 4333 KRAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYIS 4392
Query: 65 TLTVREVGPADQGSYAVIAGS 85
+L + D G Y A +
Sbjct: 4393 SLEILRTQVVDCGEYTCKASN 4413
Score = 32.0 bits (71), Expect = 3.9
Identities = 22/76 (28%), Positives = 33/76 (43%), Gaps = 1/76 (1%)
Query: 1179 EAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTL 1238
E FT+ L N V T L C V P ++ W+K ++ E R+ + ++ L
Sbjct: 5964 EEAVFTKNLANIEVSETDTIKLVCEV-SKPGAEVIWYKGDEEIIETGRYEILTEGRKRIL 6022
Query: 1239 EIRKPCPFDGGIYVCR 1254
I+ D G Y CR
Sbjct: 6023 VIQNAHLEDAGNYNCR 6038
Score = 32.0 bits (71), Expect = 3.9
Identities = 22/61 (36%), Positives = 30/61 (49%), Gaps = 2/61 (3%)
Query: 988 GEPVNLLIPFQGKPRPQVTWTKEGQPLA-GEEVSIRNSPTD-TILFIRAARRVHSGTYQV 1045
G+ V I G P P + W K+GQPL+ G + I + D L IR +G Y+V
Sbjct: 25312 GQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRV 25371
Query: 1046 T 1046
T
Sbjct: 25372 T 25372
Score = 31.6 bits (70), Expect = 5.1
Identities = 23/81 (28%), Positives = 33/81 (40%), Gaps = 5/81 (6%)
Query: 21 VAAGSPAVFEAETERAGVKV-RWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSY 79
V AG+ F A V +W GS+I Y + T+ LT++ D G Y
Sbjct: 11025 VKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEY 11084
Query: 80 AV----IAGSSKVKFDLKVIE 96
+ AGS V L V++
Sbjct: 11085 QITVSNAAGSKTVAVHLTVLD 11105
Score = 31.6 bits (70), Expect = 5.1
Identities = 25/107 (23%), Positives = 43/107 (40%), Gaps = 11/107 (10%)
Query: 18 SVEVAAGSPAVFEAETERAGVK-VRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQ 76
++ V AG EA+ + + W RG +I S + + + L V++ D
Sbjct: 17137 TIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDG 17196
Query: 77 GSYAV----IAGSSKVKFDLKVIEAEKAEPMLAPAPAPAEATGAPGE 119
G Y + +AGS ++KV++ P P + TG E
Sbjct: 17197 GQYILRASNVAGSKSFPVNVKVLDRP------GPPEGPVQVTGVTSE 17237
Score = 31.6 bits (70), Expect = 5.1
Identities = 32/96 (33%), Positives = 42/96 (43%), Gaps = 18/96 (18%)
Query: 988 GEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDT----ILFIRAARRVHSGTY 1043
GE G+P P VTW ++GQ L+ S R+ T T I + + G Y
Sbjct: 26078 GESARFSCDTDGEPVPTVTWLRKGQVLS---TSARHQVTTTKYKSTFEISSVQASDEGNY 26134
Query: 1044 QVTVRIENMEDKA----TLVLQ---VVDK--PSPPQ 1070
V V EN E K TL +Q V +K SPP+
Sbjct: 26135 SVVV--ENSEGKQEAEFTLTIQKARVTEKAVTSPPR 26168
Score = 31.2 bits (69), Expect = 6.6
Identities = 20/71 (28%), Positives = 31/71 (43%), Gaps = 1/71 (1%)
Query: 1183 FTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRK 1242
F +PL + V A C + K+ WFK+G ++ + ++ + SK V L I K
Sbjct: 5879 FLRPLTDLQVREKEMARFECEL-SRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINK 5937
Query: 1243 PCPFDGGIYVC 1253
D Y C
Sbjct: 5938 CLLDDEAEYSC 5948
Score = 31.2 bits (69), Expect = 6.6
Identities = 43/175 (24%), Positives = 71/175 (40%), Gaps = 15/175 (8%)
Query: 379 HKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRT-LTISQCSLADDAAYQCV 437
+ + L+ E +HD + L E+Q GS K T TI+ ++ +++
Sbjct: 15566 NSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATCATVKVTEATITGLIQGEEYSFRVS 15625
Query: 438 VGGEKCSTELFVKEPPV----LITRPLEDQL-----VMVGQRVEFECE-VSEEGAQVKWL 487
EK ++ PV L+ P L V+ G+ ++ + + V W
Sbjct: 15626 AQNEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWH 15685
Query: 488 KDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYA--LCTSGGQALAELIV 540
KD V L ++T + + L I +A ED GHY L S G+A+ L V
Sbjct: 15686 KDNVPL--KQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNV 15738
Score = 31.2 bits (69), Expect = 6.6
Identities = 23/87 (26%), Positives = 39/87 (44%), Gaps = 3/87 (3%)
Query: 23 AGSPAVFEAETE-RAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSY-A 80
AGSP + R KV W+ + +++ + T R TLTV++ D G Y
Sbjct: 22164 AGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFL 22223
Query: 81 VIAGSSKVK-FDLKVIEAEKAEPMLAP 106
+ ++ VK F + V+ + P+ P
Sbjct: 22224 TLENTAGVKTFSVTVVVIGRPGPVTGP 22250
Score = 31.2 bits (69), Expect = 6.6
Identities = 31/113 (27%), Positives = 44/113 (38%), Gaps = 8/113 (7%)
Query: 963 TVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPL-AGEEVSI 1021
T++ + + P LP + + VGE V + P P VTW K GQ + G+
Sbjct: 25185 TMRLLERPPEFTLPLYNKTAY---VGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKK 25241
Query: 1022 RNSPTDTILF---IRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQD 1071
+D L+ I + Y V R + ED L V P PP D
Sbjct: 25242 YTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHP-PPTD 25293
Score = 30.8 bits (68), Expect = 8.6
Identities = 22/97 (22%), Positives = 44/97 (45%), Gaps = 3/97 (3%)
Query: 981 QTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLA-GEEVSIRNSPTDTILFIRAARRVH 1039
Q + + G+P G+P+P+++W KE Q L+ G + + + L + A
Sbjct: 3200 QPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPED 3259
Query: 1040 SGTYQVTVRIEN--MEDKATLVLQVVDKPSPPQDLRV 1074
+ Y + + A+L ++V + SP Q++ V
Sbjct: 3260 AAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPV 3296
Score = 30.8 bits (68), Expect = 8.6
Identities = 20/78 (25%), Positives = 31/78 (39%)
Query: 21 VAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYA 80
V G A F E + V W + + + S +++EG H L ++EV D
Sbjct: 5088 VKEGETATFVCELSHEKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQIK 5147
Query: 81 VIAGSSKVKFDLKVIEAE 98
LKV+EA+
Sbjct: 5148 AQVKELSSTAQLKVLEAD 5165
>gi|253970427 immunoglobulin superfamily, member 22 [Homo sapiens]
Length = 1326
Score = 278 bits (711), Expect = 2e-74
Identities = 317/1322 (23%), Positives = 518/1322 (39%), Gaps = 135/1322 (10%)
Query: 4 PGKKPVSAFSKKPRSVEVAAGSPAVFEAETE-RAGVKVRWQR-GGSDISASNKYGLATEG 61
P V F +KP+ V G AVF A + A + W+R G I S K +
Sbjct: 61 PAGDSVPEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSIN 120
Query: 62 TRHTLTVREVGPADQGSYAVIAGSSKVK--FDLKVIEAEKAEPMLAPAPAPAEATGAPGE 119
H L + + D +Y IA + + + ++ E E M A AP +
Sbjct: 121 KEHVLKLEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLKKRAPPAPKK 180
Query: 120 APAPAA------ELGESAPSPKGSSSAALNGPTP-----------GAPDDPIGLFVMRP- 161
A E+ P G T + + +++P
Sbjct: 181 KQKKVANEKEMLEILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEMKKKVEVEAIRILKPL 240
Query: 162 QDGEVTVGGSITFSARVAGASLLKPPVVK--WFKGKWVDLSSKVGQHLQLHDSYDRASKV 219
+D E V ++ F + LK P VK W KG ++ L +D +K
Sbjct: 241 EDKETKVDTTVVFDCIME----LKDPNVKMIWIKGTE---PLRIQYSLGKYDVKQMGTK- 292
Query: 220 YLFELHITDAQPAFTGSYRCEVSTKDKFDCSNFNLTVHEAMGTGDLDLLSAFRRTSLAGG 279
Y +S + D ++L+V + + +L +L G
Sbjct: 293 -----------------YMLVISNVNMNDAGIYSLSVGDKRMSAELTVLD--EPLKFLGE 333
Query: 280 GRRISDSHEDTGILDFSSLLKKRDSF-------RTPRDSKLEAPAEEDVWEILRQAPPSE 332
+ + + T + + L KK +F RD K E ED L +
Sbjct: 334 MKPVKVTERQTAVFEIR-LSKKEPNFVWKFNGKELKRDDKYEITVSEDG---LTHTLKIK 389
Query: 333 YERIAFQYGVTDLRGMLKRLKGMRRDEKKSTAFQKKLEPAYQVSKGHKIRLTVELADHDA 392
R++ + G L + K ++ F L+ +V + + L EL D
Sbjct: 390 DARLSDSGEFSAEAGNLVQ-KAQLTIDRIPIKFVSNLKNV-RVKERSRACLECELTSKDV 447
Query: 393 EVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCSTELF---- 448
++W K+GQ + M G+KY G + L I L+D Y V + TE +
Sbjct: 448 TLRWKKDGQ-LLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAI 506
Query: 449 --VKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKKD 506
V+E + + D G E +++E + WLKDG E+T + + K
Sbjct: 507 VTVEERLATVKSGMSDVHAATGSPAELCVVLNDEKVEGVWLKDGKEIT--DLPGMQIVKQ 564
Query: 507 GQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKL---EVYQSIADLMVGAK--DQ 561
G H LI E G Y G ++ A + + + V +++A + K
Sbjct: 565 GAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHT 624
Query: 562 AVFKCEVSDENVRGV-WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEG 620
A K + + V W K+G E+ + R+ + LTI + D +
Sbjct: 625 AHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKN 684
Query: 621 FACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPT 680
+ +A LH + + R +PP+ GR+ + + ++ P P
Sbjct: 685 DHGSATATLH-----LSVLDRPKPPQ------GRVEFLELSGSCVHMKWKAPKDNGGRPV 733
Query: 681 ---VIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFT 737
++ ++A+ G K+ W+ + E +G+V +T
Sbjct: 734 TQFIVERRAV--GKKS-----------------WI----KIGEVDGKVTNFSTNK----- 765
Query: 738 VEGAEKEDEGVYTVT---VKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEP 794
VE + + V V +P+ ++V I+ P + P++++V +++ T+ W
Sbjct: 766 VEEGKAYQFRILAVNSEGVSDPLETEEV-FAGNPIEPPGFASQPQVTDVTKEAVTITWNA 824
Query: 795 PAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGM 854
P DGG P+LGYI+ER+KK S W+ +N D IQ ++E YE RV AVN G
Sbjct: 825 PTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGP 884
Query: 855 SRPSPASQPFM---PIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPE 911
+PS S + P+ PP L V D S++++SL WR P GY +E E
Sbjct: 885 GQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYILEMRAE 942
Query: 912 GCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRP 971
EW + T V L + FR+RA N AG G PV + V P
Sbjct: 943 DTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAP 1002
Query: 972 RLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILF 1031
+ L L+ + + G + + F G P P V W K+G P G E +I S +
Sbjct: 1003 KFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRE-TITKSKNHSQFL 1061
Query: 1032 IRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQD 1091
I + +R SG Y++ ++ E E + + ++V D P PP +LR+ + V L W D
Sbjct: 1062 INSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPD 1121
Query: 1092 VGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRA 1151
V Y + K D T W+T E V L+ G YYFRV ++N +G S+
Sbjct: 1122 VQEDGEAHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSE-P 1180
Query: 1152 ATTKEPVFIPRPGI---TYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSP 1208
+++ I + I + + Y+ D+ AP F PL +V+ G + CA G+P
Sbjct: 1181 LDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNP 1240
Query: 1209 KPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRL 1268
+P ++ +K +++ +++F S GV TL I D G Y N G+ R C L
Sbjct: 1241 RPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTL 1300
Query: 1269 EV 1270
V
Sbjct: 1301 TV 1302
>gi|148839296 immunoglobulin-like and fibronectin type III domain
containing 1 [Homo sapiens]
Length = 868
Score = 238 bits (606), Expect = 4e-62
Identities = 217/828 (26%), Positives = 329/828 (39%), Gaps = 54/828 (6%)
Query: 460 LEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAML 519
L D V G+ C ++ + W KDGV+LT ++ FK+DG H L I
Sbjct: 79 LADMEVQPGEAATLSCTLTSDLGPGTWFKDGVKLTTQDGVI--FKQDGLVHSLFITHVQG 136
Query: 520 EDAGHYALCTSGGQALAELIVQEKKL---EVYQSIAD-LMVGAKDQAVFKCEVSDE-NVR 574
AG Y Q+ A L VQ+ +V + + + L+V A + K ++
Sbjct: 137 TQAGRYTFVAGDQQSEATLTVQDSPTIAPDVTEKLREPLVVKAGKPVIVKIPFQSHLPIQ 196
Query: 575 GVWLKNGKELV--PDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFM 632
W K+G E+V D +V +L + D YS ++ A
Sbjct: 197 AAWRKDGAEVVGSSDREAQVDLGDGYTRLCLPSAGRKDCGQYSVTLRSEGGSVQA----- 251
Query: 633 EVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNK 692
E+ + + + +PP+ P + D AG LR P + Q +
Sbjct: 252 ELTLQVIDKPDPPQ----GPMEVQDCHR--AGVCLRWRPPRDNGGRTVECYVVERRQAGR 305
Query: 693 APARPAPDAPED-TGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTV 751
+ +AP D T +D V + + RVR T++ E E E+
Sbjct: 306 STWLKVGEAPADSTTFTDAHVEPGR---KYTFRVRAVTSEGAG----EALESEE------ 352
Query: 752 TVKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERK 811
+ V +P AP+AP I + T+ W P G ILGY++ER+
Sbjct: 353 ------------ILVAPEALPKAPSAPAILSASSQGITLTWTAPRGPGSAHILGYLIERR 400
Query: 812 KKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PIG 868
KK S W +N + E + +G YE RV AV G P P S P+
Sbjct: 401 KKGSNTWTAVNDQPVPERRWTVADVRQGCQYEFRVTAVAPSGPGEPGPPSDAVFARDPMR 460
Query: 869 PPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTS 928
PP +L V D S+T+++L W P+ GY VE C +W+ G T+
Sbjct: 461 PPGLVRNLQVTDRSNTSITLSWAGPDTQEGDEAQGYVVELCSSDSLQWLPCHVGTVPVTT 520
Query: 929 ILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVG 988
K L G RV A N G P V + P+ + + + KVG
Sbjct: 521 YTAKGLRPGEGYFVRVTAVNEGGQSQPSALDTLVQAMPVTVCPKFLVDSSTKDLLTVKVG 580
Query: 989 EPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVR 1048
+ V + + F+ P P+VTW K+G PL V++ T L I A SG Y V +R
Sbjct: 581 DTVRVPVSFEAMPMPEVTWLKDGLPLPKRSVTVTKDGL-TQLLIPVAGLSDSGLYTVVLR 639
Query: 1049 -IENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADK 1107
++ E + ++V P P + + + V EW+P D Y V
Sbjct: 640 TLQGKEVAHSFRIRVAACPQAPGPIHLQENVPGTVTAEWEPSPDEAQDVPLHYAVFTRSS 699
Query: 1108 KTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIP--RPGI 1165
W + + ++ G+ Y+FRV ++N +G S + + T +P IP R
Sbjct: 700 AHGPWHEAADRIHTNRFTLLGILPGHEYHFRVVAKNELGAS-KPSDTSQPWCIPRQRDRF 758
Query: 1166 TYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDA 1225
T + P Y+ D S+ P F L + + G + CAV+GSP+P ++WFKN L +
Sbjct: 759 TVKAPCYREPDLSQKPRFLVGLRSHLLPQGCECCMSCAVQGSPRPHVTWFKNDRSLEGNP 818
Query: 1226 RFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVRVP 1273
GV +L I P D G Y A N G+A L V P
Sbjct: 819 AVYSTDLLGVCSLTIPSVSPKDSGEYKAVAENTLGQAVSTATLIVIEP 866
Score = 125 bits (313), Expect = 3e-28
Identities = 99/427 (23%), Positives = 171/427 (40%), Gaps = 41/427 (9%)
Query: 549 QSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTP 608
Q +AD+ V + A C ++ + G W K+G +L + G VH L I V
Sbjct: 77 QGLADMEVQPGEAATLSCTLTSDLGPGTWFKDGVKLTTQDGVIFKQDGLVHSLFITHVQG 136
Query: 609 ADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLR 668
Y+FV + + Q+ P I D ++ + +VV AG +
Sbjct: 137 TQAGRYTFVAGDQQSEATLTV------------QDSPTIAPDVTEKLREPLVVKAGKPVI 184
Query: 669 LDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVE 728
+ +P W+K D E G SD +V+
Sbjct: 185 VKIPFQSHLPIQAAWRK--------------DGAEVVGSSDR-------------EAQVD 217
Query: 729 TTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAP-KISNVGEDS 787
+ + A ++D G Y+VT+++ G Q LT++VID PD P P ++ +
Sbjct: 218 LGDGYTRLCLPSAGRKDCGQYSVTLRSEGGSVQAELTLQVIDKPDPPQGPMEVQDCHRAG 277
Query: 788 CTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVY 847
++W PP +GG+ + Y++ER++ W+++ + + G Y RV
Sbjct: 278 VCLRWRPPRDNGGRTVECYVVERRQAGRSTWLKVGEAPADSTTFTDAHVEPGRKYTFRVR 337
Query: 848 AVNAIGMSRPSPASQPFM-PIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSV 906
AV + G + + + P P P+ A+ S ++L W P G+ + GY +
Sbjct: 338 AVTSEGAGEALESEEILVAPEALPKAPSAPAILSASSQGITLTWTAPRGPGSAHILGYLI 397
Query: 907 EYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQE 966
E +G + W A V D+ G + FRV A +GPG P ++ V ++
Sbjct: 398 ERRKKGSNTWTAVNDQPVPERRWTVADVRQGCQYEFRVTAVAPSGPGEPGPPSDAVFARD 457
Query: 967 ILQRPRL 973
++ P L
Sbjct: 458 PMRPPGL 464
>gi|58331253 obscurin, cytoskeletal calmodulin and titin-interacting
RhoGEF isoform a [Homo sapiens]
Length = 6620
Score = 151 bits (381), Expect = 4e-36
Identities = 179/739 (24%), Positives = 285/739 (38%), Gaps = 113/739 (15%)
Query: 7 KPVSAFSKKP---RSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTR 63
+P F+K+ V+ AG+ A+ E +A +V W + G +S+S+K G+ +G
Sbjct: 1069 EPKMMFAKEQSVHNEVQAEAGASAMLSCEVAQAQTEVTWYKDGKKLSSSSKVGMEVKGCT 1128
Query: 64 HTLTVREVGPADQGSYAVIAGSSKVKFDLKVIEAE----KAEPMLAPAPAPAEATGAPG- 118
L + + G AD G Y+ AG +V F L + E + K + + A A T
Sbjct: 1129 RRLVLPQAGKADAGEYSCEAGGQRVSFHLHITEPKGVFAKEQSVHNEVQAEAGTTAMLSC 1188
Query: 119 EAPAPAAELGESAPSPKGSSSAALNGPTPGAPDDPIGLFVMRPQDGEVT----------- 167
E P E+ K SSS+ + G + V + GE +
Sbjct: 1189 EVAQPQTEVTWYKDGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEYSCEAGGQRVSFQ 1248
Query: 168 -----------------------VGGSITFSARVAGASLLKPPVVKWFK-GKWVDLSSKV 203
G S T S VA A V W+K GK + SSKV
Sbjct: 1249 LHITEPKAVFAKEQLVHNEVRTEAGASATLSCEVAQAQT----EVTWYKDGKKLSSSSKV 1304
Query: 204 GQHLQLHDSYDRASKVYLFELHITDAQPAFTGSYRCEVSTKDKFDCSNFNLTVHEAMGTG 263
+ + +L + A A G Y CE + +F+L V E
Sbjct: 1305 RIE----------AAGCMRQLVVQQAGQADAGEYTCEAGGQRL----SFHLDVSEPKAVF 1350
Query: 264 DLDLLSAFRRTSLAGGGRRISDSHEDTGILDFSSLLKKRDSFRTPRDSKLEAPA----EE 319
+ L+ + + AG +S + + +D + SK+ A
Sbjct: 1351 AKEQLAHRKVQAEAGAIATLSCEVAQAQ----TEVTWYKDGKKLSSSSKVRMEAVGCTRR 1406
Query: 320 DVWEILRQAPPSEY------ERIAFQYGVTDLRGMLKRLKGMRRDEKKSTAFQKKLEPAY 373
V + QA EY +R++F V + + + + + + R+
Sbjct: 1407 LVVQQACQADTGEYSCEAGGQRLSFSLDVAEPKVVFAKEQPVHRE--------------V 1452
Query: 374 QVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAA 433
Q G L+ E+A EV W K+G+++ S SK E++G R L + Q A
Sbjct: 1453 QAQAGASTTLSCEVAQAQTEVMWYKDGKKLSFS-SKVRMEAVGCTRRLVVQQAGQAVAGE 1511
Query: 434 YQCVVGGEKCSTELFVKEPPVLITR--PLEDQL-VMVGQRVEFECEVSEEGAQVKWLKDG 490
Y C G ++ S L V EP + + P ++ G CEV++ +V W KDG
Sbjct: 1512 YSCEAGSQRLSFHLHVAEPKAVFAKEQPASREVQAEAGTSATLSCEVAQAQTEVTWYKDG 1571
Query: 491 VELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALA-ELIVQEKKL---E 546
+L+ K R + G L++ EA DAG Y+ C +G Q L+ L V E K+ +
Sbjct: 1572 KKLSSSS--KVRMEAVGCTRRLVVQEAGQADAGEYS-CKAGDQRLSFHLHVAEPKVVFAK 1628
Query: 547 VYQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDV 606
+ ++ A A CEV+ W K+GK+L S+++V +G +L +
Sbjct: 1629 EQPAHREVQAEAGASATLSCEVAQAQTEVTWYKDGKKLSSSSKVRVEAVGCTRRLVVQQA 1688
Query: 607 TPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNK 666
AD +YS E LS +LH E+ EP C + +VV
Sbjct: 1689 GQADAGEYSC--EAGGQRLSFRLHVAEL--------EPQISERPCR---REPLVVKEHED 1735
Query: 667 LRLDVPISGDPAPTVIWQK 685
+ L ++ A TV W K
Sbjct: 1736 IILTATLATPSAATVTWLK 1754
Score = 149 bits (376), Expect = 2e-35
Identities = 173/683 (25%), Positives = 266/683 (38%), Gaps = 102/683 (14%)
Query: 19 VEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATE-GTRHTLTVREVGPADQG 77
V+ AG PA FE ET A V V W + G ++ S + L + GTRH L V D+G
Sbjct: 807 VDAVAGGPAQFECETSEAHVHVHWYKDGMELGHSGERFLQEDVGTRHRLVAATVTRQDEG 866
Query: 78 SYAVIAGSSKVKFDLKVIEAEK--AEPMLAPAPAPAEATGAPGEAPAPAAEL-------- 127
+Y+ G V F L+V E + A+ LA AEA GA A+
Sbjct: 867 TYSCRVGEDSVDFRLRVSEPKVVFAKEQLARRKLQAEA-GASATLSCEVAQAQTEVTWYK 925
Query: 128 -GESAPSPK------------------GSSSAALNGPTPGAPDDPIGLFVMRPQ------ 162
G+ S G + A G L V P+
Sbjct: 926 DGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEYSCEAGGQRLSFHLDVKEPKVVFAKD 985
Query: 163 -----DGEVTVGGSITFSARVAGASLLKPPVVKWFK-GKWVDLSSKVGQHLQLHDSYDRA 216
+ + G S T S VA A V W+K GK LSS + H++ R
Sbjct: 986 QVAHSEVQAEAGASATLSCEVAQAQ----TEVMWYKDGK--KLSSSLKVHVEAKGCRRR- 1038
Query: 217 SKVYLFELHITDAQPAFTGSYRCEVSTKDKFDCSNFNLTVHEAMGTGDLDLLSAFRRTSL 276
L + A G Y CE + + ++T + M + + + + +
Sbjct: 1039 -------LVVQQAGKTDAGDYSCE--ARGQRVSFRLHITEPKMMFAKEQSVHNEVQAEAG 1089
Query: 277 AGGGRRISDSHEDTGILDFSSLLKKRDSFRTPRDSK-------LEAPAEEDVWEILRQAP 329
A + T + + K S + + K L + D E +A
Sbjct: 1090 ASAMLSCEVAQAQTEVTWYKDGKKLSSSSKVGMEVKGCTRRLVLPQAGKADAGEYSCEAG 1149
Query: 330 PSEYERIAFQYGVTDLRGMLKRLKGMRRDEKKSTAFQKKLEPAYQVSKGHKIRLTVELAD 389
+R++F +T+ +G+ A ++ + Q G L+ E+A
Sbjct: 1150 G---QRVSFHLHITEPKGVF--------------AKEQSVHNEVQAEAGTTAMLSCEVAQ 1192
Query: 390 HDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCSTELFV 449
EV W K+G+++ S SK E G R L + Q AD Y C GG++ S +L +
Sbjct: 1193 PQTEVTWYKDGKKLS-SSSKVRMEVKGCTRRLVVQQVGKADAGEYSCEAGGQRVSFQLHI 1251
Query: 450 KEPPVLITRPLEDQLV------MVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRF 503
EP + + +QLV G CEV++ +V W KDG +L+ + K R
Sbjct: 1252 TEPKAVFAK---EQLVHNEVRTEAGASATLSCEVAQAQTEVTWYKDGKKLS--SSSKVRI 1306
Query: 504 KKDGQRHHLIINEAMLEDAGHYALCTSGGQALA-ELIVQE-KKLEVYQSIADLMVGAKDQ 561
+ G L++ +A DAG Y C +GGQ L+ L V E K + + +A V A+
Sbjct: 1307 EAAGCMRQLVVQQAGQADAGEYT-CEAGGQRLSFHLDVSEPKAVFAKEQLAHRKVQAEAG 1365
Query: 562 AV--FKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPE 619
A+ CEV+ W K+GK+L S++++ +G +L + AD +YS E
Sbjct: 1366 AIATLSCEVAQAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQQACQADTGEYSC--E 1423
Query: 620 GFACNLSAKLHFMEVKIDFVPRQ 642
LS L E K+ F Q
Sbjct: 1424 AGGQRLSFSLDVAEPKVVFAKEQ 1446
Score = 142 bits (357), Expect = 3e-33
Identities = 169/691 (24%), Positives = 275/691 (39%), Gaps = 92/691 (13%)
Query: 7 KPVSAFSKKP---RSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTR 63
+P F+K+ R ++ AG+ A E +A +V W + G +S+S+K + G
Sbjct: 885 EPKVVFAKEQLARRKLQAEAGASATLSCEVAQAQTEVTWYKDGKKLSSSSKVCMEATGCT 944
Query: 64 HTLTVREVGPADQGSYAVIAGSSKVKFDLKVIEAEK--AEPMLAPAPAPAEATGAPG--- 118
L V++ G AD G Y+ AG ++ F L V E + A+ +A + AEA GA
Sbjct: 945 RRLVVQQAGQADAGEYSCEAGGQRLSFHLDVKEPKVVFAKDQVAHSEVQAEA-GASATLS 1003
Query: 119 -EAPAPAAELGESAPSPKGSSSAALNGPTPGAPDDPIGLFVMRPQDGEVTV---GGSITF 174
E E+ K SSS ++ G + + G+ + G ++F
Sbjct: 1004 CEVAQAQTEVMWYKDGKKLSSSLKVHVEAKGCRRRLVVQQAGKTDAGDYSCEARGQRVSF 1063
Query: 175 SARV--------------------AGASLL-------KPPVVKWFK-GKWVDLSSKVGQH 206
+ AGAS + V W+K GK + SSKVG
Sbjct: 1064 RLHITEPKMMFAKEQSVHNEVQAEAGASAMLSCEVAQAQTEVTWYKDGKKLSSSSKVGME 1123
Query: 207 LQLHDSYDRASKVYLFELHITDAQPAFTGSYRCEVSTKDKFDCSNFNLTVHEAMGTGDLD 266
+ K L + A A G Y CE + +F+L + E G +
Sbjct: 1124 V----------KGCTRRLVLPQAGKADAGEYSCEAGGQR----VSFHLHITEPKGVFAKE 1169
Query: 267 LLSAFRRTSLAGGGRRIS--DSHEDTGILDFSSLLKKRDSFRTPRDSKLEAPAEEDVWEI 324
+ AG +S + T + + K S + + K V +
Sbjct: 1170 QSVHNEVQAEAGTTAMLSCEVAQPQTEVTWYKDGKKLSSSSKVRMEVK--GCTRRLVVQQ 1227
Query: 325 LRQAPPSEY------ERIAFQYGVTDLRGMLKRLKGMRRDEKKSTAFQKKLEPAYQVSKG 378
+ +A EY +R++FQ +T+ + + A ++ + + G
Sbjct: 1228 VGKADAGEYSCEAGGQRVSFQLHITEPKAVF--------------AKEQLVHNEVRTEAG 1273
Query: 379 HKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVV 438
L+ E+A EV W K+G+++ S SK E+ G R L + Q AD Y C
Sbjct: 1274 ASATLSCEVAQAQTEVTWYKDGKKLS-SSSKVRIEAAGCMRQLVVQQAGQADAGEYTCEA 1332
Query: 439 GGEKCSTELFVKEPPVLITR-PLEDQLVM--VGQRVEFECEVSEEGAQVKWLKDGVELTR 495
GG++ S L V EP + + L + V G CEV++ +V W KDG +L+
Sbjct: 1333 GGQRLSFHLDVSEPKAVFAKEQLAHRKVQAEAGAIATLSCEVAQAQTEVTWYKDGKKLS- 1391
Query: 496 EETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALA-ELIVQEKKLEVYQS---I 551
+ K R + G L++ +A D G Y+ C +GGQ L+ L V E K+ +
Sbjct: 1392 -SSSKVRMEAVGCTRRLVVQQACQADTGEYS-CEAGGQRLSFSLDVAEPKVVFAKEQPVH 1449
Query: 552 ADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADE 611
++ A CEV+ +W K+GK+L S++++ +G +L + A
Sbjct: 1450 REVQAQAGASTTLSCEVAQAQTEVMWYKDGKKLSFSSKVRMEAVGCTRRLVVQQAGQAVA 1509
Query: 612 ADYSFVPEGFACNLSAKLHFMEVKIDFVPRQ 642
+YS E + LS LH E K F Q
Sbjct: 1510 GEYSC--EAGSQRLSFHLHVAEPKAVFAKEQ 1538
Score = 140 bits (353), Expect = 8e-33
Identities = 167/697 (23%), Positives = 273/697 (39%), Gaps = 102/697 (14%)
Query: 6 KKPVSAFSKKP---RSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGT 62
K+P F+K V+ AG+ A E +A +V W + G +S+S K + +G
Sbjct: 976 KEPKVVFAKDQVAHSEVQAEAGASATLSCEVAQAQTEVMWYKDGKKLSSSLKVHVEAKGC 1035
Query: 63 RHTLTVREVGPADQGSYAVIAGSSKVKFDLKVIEAEK-----------------AEPMLA 105
R L V++ G D G Y+ A +V F L + E + A ML+
Sbjct: 1036 RRRLVVQQAGKTDAGDYSCEARGQRVSFRLHITEPKMMFAKEQSVHNEVQAEAGASAMLS 1095
Query: 106 --PAPAPAEATG-APGEAPAPAAELG-------------ESAPSPKGSSSAALNGPTPGA 149
A A E T G+ + ++++G ++ + G S G
Sbjct: 1096 CEVAQAQTEVTWYKDGKKLSSSSKVGMEVKGCTRRLVLPQAGKADAGEYSCEAGGQRVSF 1155
Query: 150 P---DDPIGLFVMRPQ---DGEVTVGGSITFSARVAGASLLKPPVVKWFK-GKWVDLSSK 202
+P G+F + + G + S VA V W+K GK + SSK
Sbjct: 1156 HLHITEPKGVFAKEQSVHNEVQAEAGTTAMLSCEVAQPQT----EVTWYKDGKKLSSSSK 1211
Query: 203 VGQHLQLHDSYDRASKVYLFELHITDAQPAFTGSYRCEVSTKDKFDCSNFNLTVHEAMGT 262
V + K L + A G Y CE + +F L + E
Sbjct: 1212 VRMEV----------KGCTRRLVVQQVGKADAGEYSCEAGGQRV----SFQLHITEPKAV 1257
Query: 263 GDLDLLSAFRRTSLAGGGRRISDSHEDTGILDFSSLLKKRDSFRTPRDSKLEAPAEEDVW 322
+ L + AG +S + + +D + SK+ A +
Sbjct: 1258 FAKEQLVHNEVRTEAGASATLSCEVAQAQ----TEVTWYKDGKKLSSSSKVRIEAAGCMR 1313
Query: 323 EIL----RQAPPSEY------ERIAFQYGVTDLRGMLKRLKGMRRDEKKSTAFQKKLEPA 372
+++ QA EY +R++F V++ + + K+ A +K
Sbjct: 1314 QLVVQQAGQADAGEYTCEAGGQRLSFHLDVSEPKAVFA---------KEQLAHRK----- 1359
Query: 373 YQVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDA 432
Q G L+ E+A EV W K+G+++ S SK E++G R L + Q AD
Sbjct: 1360 VQAEAGAIATLSCEVAQAQTEVTWYKDGKKLS-SSSKVRMEAVGCTRRLVVQQACQADTG 1418
Query: 433 AYQCVVGGEKCSTELFVKEPPVLITR--PLEDQL-VMVGQRVEFECEVSEEGAQVKWLKD 489
Y C GG++ S L V EP V+ + P+ ++ G CEV++ +V W KD
Sbjct: 1419 EYSCEAGGQRLSFSLDVAEPKVVFAKEQPVHREVQAQAGASTTLSCEVAQAQTEVMWYKD 1478
Query: 490 GVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALA-ELIVQEKK---L 545
G +L+ K R + G L++ +A AG Y+ C +G Q L+ L V E K
Sbjct: 1479 GKKLSFSS--KVRMEAVGCTRRLVVQQAGQAVAGEYS-CEAGSQRLSFHLHVAEPKAVFA 1535
Query: 546 EVYQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDD 605
+ + ++ A A CEV+ W K+GK+L S++++ +G +L + +
Sbjct: 1536 KEQPASREVQAEAGTSATLSCEVAQAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQE 1595
Query: 606 VTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQ 642
AD +YS + LS LH E K+ F Q
Sbjct: 1596 AGQADAGEYSC--KAGDQRLSFHLHVAEPKVVFAKEQ 1630
Score = 120 bits (301), Expect = 8e-27
Identities = 158/702 (22%), Positives = 260/702 (37%), Gaps = 95/702 (13%)
Query: 28 VFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYAVIAGSSK 87
V E + RA +VRW +G ++ KY L ++G L + +V D+ +Y AG K
Sbjct: 2308 VLECQVSRASAQVRWFKGSQELQPGPKYELVSDGLYRKLIISDVHAEDEDTYTCDAGDVK 2367
Query: 88 VKFD-------LKVIEAEKAEPMLAPAPAPAEA-TGAPGEAPAPAAELGESAPSPKGS-- 137
+ ++ + ++ PAPA E T P P P LG++ G+
Sbjct: 2368 TSAQFFVEEQSITIVRGLQDVTVMEPAPAWFECETSIPSVRP-PKWLLGKTVLQAGGNVG 2426
Query: 138 --------------SSAALNGP---TPGAPDDPIGLFV----------MRPQDGEVTVGG 170
+ + + GP T G L V + P+ G
Sbjct: 2427 LEQEGTVHRLMLRRTCSTMTGPVHFTVGKSRSSARLVVSDIPVVLTRPLEPKTGRELQSV 2486
Query: 171 SITFSARVAGASLLKPPVVKWFKGKWVDLSSKVGQHLQLHDSYDRASKVYLFELHITDAQ 230
++ R A P V+W+K L + + + + + EL I
Sbjct: 2487 VLSCDFRPA------PKAVQWYKDD---------TPLSPSEKFKMSLEGQMAELRILRLM 2531
Query: 231 PAFTGSYRCEVSTKDKFDCSNFNLTVHEAMGTGDLDLLSAFRRTSLAGGGRRISDSHEDT 290
PA G YRC+ + + + E TG L A T SHED
Sbjct: 2532 PADAGVYRCQAGSAHS--STEVTVEAREVTVTGPLQDAEA---TEEGWASFSCELSHEDE 2586
Query: 291 GI-LDFSSLLKKRDSFRTPRDSKLEAPAEEDVWEILRQAPPSEYERIAFQYGVTDLRGML 349
+ + + DSF + + V + +++A G+ +
Sbjct: 2587 EVEWSLNGMPLYNDSFH---EISHKGRRHTLVLKSIQRADA----------GIVRASSLK 2633
Query: 350 KRLKGMRRDEKKSTAFQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSK 409
K F K L+ +G + L E++D +A V W K+G ++ S K
Sbjct: 2634 VSTSARLEVRVKPVVFLKALDDLSAEERG-TLALQCEVSDPEAHVVWRKDGVQLGPS-DK 2691
Query: 410 YIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQ 469
Y F R L + S D Y C VG E+ + V + V IT+ L+ V+ G+
Sbjct: 2692 YDFLHTAGTRGLVVHDVSPEDAGLYTCHVGSEETRARVRVHDLHVGITKRLKTMEVLEGE 2751
Query: 470 RVEFECEVSEEGAQ--VKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYAL 527
FEC +S E A W G T + +++ + G+++ L++ EA DAG
Sbjct: 2752 SCSFECVLSHESASDPAMWTVGG--KTVGSSSRFQATRQGRKYILVVREAAPSDAGEVVF 2809
Query: 528 CTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPD 587
G + A LIV+E+ + + + D V + +CE+S WLK+ K +
Sbjct: 2810 SVRGLTSKASLIVRERPAAIIKPLEDQWVAPGEDVELRCELSRAGTPVHWLKDRKAIRKS 2869
Query: 588 SRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKI 647
+ V G + L I + D +Y+ E A +A LH E F +E +
Sbjct: 2870 QKYDVVCEGTMAMLVIRGASLKDAGEYTCEVE--ASKSTASLHVEEKANCFT--EELTNL 2925
Query: 648 HLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQ 689
++ G T V + PA TV W+K + +
Sbjct: 2926 QVEEKG----TAVFTCKTE---------HPAATVTWRKGLLE 2954
Score = 118 bits (295), Expect = 4e-26
Identities = 154/668 (23%), Positives = 251/668 (37%), Gaps = 97/668 (14%)
Query: 31 AETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYAVIAGSSKVKF 90
AE V W + G +S KY + R L VR+V D G Y ++ ++ +
Sbjct: 728 AELSDQAAAVTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYECVSRGGRIAY 787
Query: 91 DLKV------IEAEKAEPML-APAPAPAEATGAPGEAPA------PAAELG--------E 129
L V + + A + A A PA+ EA ELG E
Sbjct: 788 QLSVQGLARFLHKDMAGSCVDAVAGGPAQFECETSEAHVHVHWYKDGMELGHSGERFLQE 847
Query: 130 SAPSPKGSSSAALNGPTPGAPDDPIGL----FVMRPQDGEVT--------------VGGS 171
+ +A + G +G F +R + +V G S
Sbjct: 848 DVGTRHRLVAATVTRQDEGTYSCRVGEDSVDFRLRVSEPKVVFAKEQLARRKLQAEAGAS 907
Query: 172 ITFSARVAGASLLKPPVVKWFK-GKWVDLSSKVGQHLQLHDSYDRASKVYLFELHITDAQ 230
T S VA A V W+K GK + SSKV + L + A
Sbjct: 908 ATLSCEVAQAQ----TEVTWYKDGKKLSSSSKVCME----------ATGCTRRLVVQQAG 953
Query: 231 PAFTGSYRCEVSTKDKFDCSNFNLTVHEAMGTGDLDLLSAFRRTSLAGGGRRIS--DSHE 288
A G Y CE + +F+L V E D ++ + AG +S +
Sbjct: 954 QADAGEYSCEAGGQR----LSFHLDVKEPKVVFAKDQVAHSEVQAEAGASATLSCEVAQA 1009
Query: 289 DTGILDFSSLLKKRDSFRTPRDSK-------LEAPAEEDVWEILRQAPPSEYERIAFQYG 341
T ++ + K S + ++K ++ + D + +A +R++F+
Sbjct: 1010 QTEVMWYKDGKKLSSSLKVHVEAKGCRRRLVVQQAGKTDAGDYSCEA---RGQRVSFRLH 1066
Query: 342 VTDLRGMLKRLKGMRRDEKKSTAFQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQ 401
+T+ + M A ++ + Q G L+ E+A EV W K+G+
Sbjct: 1067 ITEPKMMF--------------AKEQSVHNEVQAEAGASAMLSCEVAQAQTEVTWYKDGK 1112
Query: 402 EIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCSTELFVKEPPVLITRPL- 460
++ S SK E G R L + Q AD Y C GG++ S L + EP + +
Sbjct: 1113 KLS-SSSKVGMEVKGCTRRLVLPQAGKADAGEYSCEAGGQRVSFHLHITEPKGVFAKEQS 1171
Query: 461 --EDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAM 518
+ G CEV++ +V W KDG +L+ + K R + G L++ +
Sbjct: 1172 VHNEVQAEAGTTAMLSCEVAQPQTEVTWYKDGKKLS--SSSKVRMEVKGCTRRLVVQQVG 1229
Query: 519 LEDAGHYALCTSGGQALA-ELIVQEKKLEVYQSIA---DLMVGAKDQAVFKCEVSDENVR 574
DAG Y+ C +GGQ ++ +L + E K + ++ A A CEV+
Sbjct: 1230 KADAGEYS-CEAGGQRVSFQLHITEPKAVFAKEQLVHNEVRTEAGASATLSCEVAQAQTE 1288
Query: 575 GVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEV 634
W K+GK+L S++++ G + +L + AD +Y+ E LS L E
Sbjct: 1289 VTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEYTC--EAGGQRLSFHLDVSEP 1346
Query: 635 KIDFVPRQ 642
K F Q
Sbjct: 1347 KAVFAKEQ 1354
Score = 115 bits (287), Expect = 3e-25
Identities = 88/318 (27%), Positives = 134/318 (42%), Gaps = 23/318 (7%)
Query: 374 QVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAA 433
Q G L+ E+A EV W K+G+++ S SK E+ G R L + Q AD
Sbjct: 901 QAEAGASATLSCEVAQAQTEVTWYKDGKKLS-SSSKVCMEATGCTRRLVVQQAGQADAGE 959
Query: 434 YQCVVGGEKCSTELFVKEPPVLITRPL---EDQLVMVGQRVEFECEVSEEGAQVKWLKDG 490
Y C GG++ S L VKEP V+ + + G CEV++ +V W KDG
Sbjct: 960 YSCEAGGQRLSFHLDVKEPKVVFAKDQVAHSEVQAEAGASATLSCEVAQAQTEVMWYKDG 1019
Query: 491 VELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKL--EVY 548
+L+ + K + G R L++ +A DAG Y+ G + L + E K+
Sbjct: 1020 KKLS--SSLKVHVEAKGCRRRLVVQQAGKTDAGDYSCEARGQRVSFRLHITEPKMMFAKE 1077
Query: 549 QSI-ADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVT 607
QS+ ++ A A+ CEV+ W K+GK+L S++ + G +L +
Sbjct: 1078 QSVHNEVQAEAGASAMLSCEVAQAQTEVTWYKDGKKLSSSSKVGMEVKGCTRRLVLPQAG 1137
Query: 608 PADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKL 667
AD +YS E +S LH E K F Q + + + AG
Sbjct: 1138 KADAGEYSC--EAGGQRVSFHLHITEPKGVFAKEQS-----------VHNEVQAEAGTTA 1184
Query: 668 RLDVPISGDPAPTVIWQK 685
L ++ P V W K
Sbjct: 1185 MLSCEVA-QPQTEVTWYK 1201
Score = 111 bits (278), Expect = 4e-24
Identities = 84/257 (32%), Positives = 123/257 (47%), Gaps = 8/257 (3%)
Query: 365 FQKKLEPAYQVSKGHKIRLTVELADHD--AEVKWLKNGQEIQMSGSKYIFESIGAKRTLT 422
F+ +L+ Q + G RL +L+D + A V+WLK G E+ +G KY S GA R L
Sbjct: 4070 FKTRLQSLEQET-GDIARLCCQLSDAESGAVVQWLKEGVELH-AGPKYEMRSQGATRELL 4127
Query: 423 ISQCSLADDAAYQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGA 482
I Q D Y CV GG+K + L V EP V I R L D V + VEF CEVS GA
Sbjct: 4128 IHQLEAKDTGEYACVTGGQKTAASLRVTEPEVTIVRGLVDAEVTADEDVEFSCEVSRAGA 4187
Query: 483 Q-VKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQ 541
V+W G+ L E + +DG+ H L + EDAG + + A+L V+
Sbjct: 4188 TGVQWCLQGLPLQSNEVTEVAV-RDGRIHTLRLKGVTPEDAGTVSFHLGNHASSAQLTVR 4246
Query: 542 EKKLEVYQSIADLMVGAKDQAVFKCEVSDENVRGV-WLKNGKELVPDSRIKVS-HIGRVH 599
++ + + + D+ + A F+C +S + + W G L + ++ G +H
Sbjct: 4247 APEVTILEPLQDVQLSEGQDASFQCRLSRASGQEARWALGGVPLQANEMNDITVEQGTLH 4306
Query: 600 KLTIDDVTPADEADYSF 616
LT+ VT D SF
Sbjct: 4307 LLTLHKVTLEDAGTVSF 4323
Score = 105 bits (262), Expect = 3e-22
Identities = 78/276 (28%), Positives = 118/276 (42%), Gaps = 40/276 (14%)
Query: 364 AFQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTI 423
+F + L+ K K+ L EL+ + +V+WLK+G E++ +G + GA R+LTI
Sbjct: 2167 SFSRPLQDVVTTEK-EKVTLECELSRPNVDVRWLKDGVELR-AGKTMAIAAQGACRSLTI 2224
Query: 424 SQCSLADDAAYQC-----------------------------------VVGGEKCSTELF 448
+C AD Y C V + +L
Sbjct: 2225 YRCEFADQGVYVCDAHDAQSSASVKVQGRTYTLIYRRVLAEDAGEIQFVAENAESRAQLR 2284
Query: 449 VKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKKDGQ 508
VKE PV + RPL D++ M R EC+VS AQV+W K EL + KY DG
Sbjct: 2285 VKELPVTLVRPLRDKIAMEKHRGVLECQVSRASAQVRWFKGSQEL--QPGPKYELVSDGL 2342
Query: 509 RHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFKCEV 568
LII++ ED Y + A+ V+E+ + + + + D+ V A F+CE
Sbjct: 2343 YRKLIISDVHAEDEDTYTCDAGDVKTSAQFFVEEQSITIVRGLQDVTVMEPAPAWFECET 2402
Query: 569 SDENVR-GVWLKNGKELVPDSRIKVSHIGRVHKLTI 603
S +VR WL L + + G VH+L +
Sbjct: 2403 SIPSVRPPKWLLGKTVLQAGGNVGLEQEGTVHRLML 2438
Score = 102 bits (253), Expect = 3e-21
Identities = 79/267 (29%), Positives = 113/267 (42%), Gaps = 7/267 (2%)
Query: 374 QVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAA 433
+V +G L EL+ A V+W K ++ +KY GA L + D
Sbjct: 3989 EVDEGGTAHLCCELSRAGASVEWRKGSLQL-FPCAKYQMVQDGAAAELLVRGVEQEDAGD 4047
Query: 434 YQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVS--EEGAQVKWLKDGV 491
Y C G + L V+ P L+ G C++S E GA V+WLK+GV
Sbjct: 4048 YTCDTGHTQSMASLSVRVPRPKFKTRLQSLEQETGDIARLCCQLSDAESGAVVQWLKEGV 4107
Query: 492 ELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSI 551
EL KY + G L+I++ +D G YA T G + A L V E ++ + + +
Sbjct: 4108 ELHAGP--KYEMRSQGATRELLIHQLEAKDTGEYACVTGGQKTAASLRVTEPEVTIVRGL 4165
Query: 552 ADLMVGAKDQAVFKCEVSDENVRGV-WLKNGKELVPDSRIKVS-HIGRVHKLTIDDVTPA 609
D V A + F CEVS GV W G L + +V+ GR+H L + VTP
Sbjct: 4166 VDAEVTADEDVEFSCEVSRAGATGVQWCLQGLPLQSNEVTEVAVRDGRIHTLRLKGVTPE 4225
Query: 610 DEADYSFVPEGFACNLSAKLHFMEVKI 636
D SF A + + EV I
Sbjct: 4226 DAGTVSFHLGNHASSAQLTVRAPEVTI 4252
Score = 100 bits (249), Expect = 9e-21
Identities = 105/396 (26%), Positives = 162/396 (40%), Gaps = 42/396 (10%)
Query: 375 VSKGHKIRLTVELADHDAE-VKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAA 433
V + I LT LA A V WLK+G EI+ S ++ S G TLT+ + D A
Sbjct: 1730 VKEHEDIILTATLATPSAATVTWLKDGVEIRRS-KRHETASQGDTHTLTVHGAQVLDSAI 1788
Query: 434 YQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVEL 493
Y C VG E + V+E R LE +G V CE+S A+V W +L
Sbjct: 1789 YSCRVGAEGQDFPVQVEEVAAKFCRLLEPVCGELGGTVTLACELSPACAEVVWRCGNTQL 1848
Query: 494 TREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIAD 553
+ F+ +G L + EDAG Y + A+L V ++ + S
Sbjct: 1849 RVGKRFQ--MVAEGPVRSLTVLGLRAEDAGEYVCESRDDHTSAQLTVSVPRVVKFMSGLS 1906
Query: 554 LMVGAKD-QAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEA 612
+V + +A F+C VS +V VW ++G L P + +S G H LTI D+ D
Sbjct: 1907 TVVAEEGGEATFQCVVSPSDVAVVWFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAG 1966
Query: 613 DYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVP 672
+ EG + SA L E + F + EP V + + L+V
Sbjct: 1967 QITVEAEG--ASSSAALRVREAPVLFKKKLEPQ--------------TVEERSSVTLEVE 2010
Query: 673 ISGDPAPTVIWQKAITQGNKAPARPAPDAPE---------DTGDSDEWVFDKKLLCE--- 720
++ P P + W + T AP + E + G +D F CE
Sbjct: 2011 LT-RPWPELRWTRNATA--LAPGKNVEIHAEGARHRLVLHNVGFADRGFFG----CETPD 2063
Query: 721 --TEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVK 754
T+ ++ VE + R + ++ E ++G T+ V+
Sbjct: 2064 DKTQAKLTVEMRQVRLVRGLQAVEAREQGTATMEVQ 2099
Score = 100 bits (248), Expect = 1e-20
Identities = 72/266 (27%), Positives = 112/266 (42%), Gaps = 34/266 (12%)
Query: 383 LTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEK 442
+ V+L+ D + W ++G Q + ++ G TLT+S D G
Sbjct: 2096 MEVQLSHADVDGSWTRDGLRFQQGPTCHLAVR-GPMHTLTLSGLRPEDSGLMVFKAEGVH 2154
Query: 443 CSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFK-- 500
S L V E PV +RPL+D + ++V ECE+S V+WLKDGVEL +T
Sbjct: 2155 TSARLVVTELPVSFSRPLQDVVTTEKEKVTLECELSRPNVDVRWLKDGVELRAGKTMAIA 2214
Query: 501 ----------YR---------------------FKKDGQRHHLIINEAMLEDAGHYALCT 529
YR K G+ + LI + EDAG
Sbjct: 2215 AQGACRSLTIYRCEFADQGVYVCDAHDAQSSASVKVQGRTYTLIYRRVLAEDAGEIQFVA 2274
Query: 530 SGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSR 589
++ A+L V+E + + + + D + K + V +C+VS + + W K +EL P +
Sbjct: 2275 ENAESRAQLRVKELPVTLVRPLRDKIAMEKHRGVLECQVSRASAQVRWFKGSQELQPGPK 2334
Query: 590 IKVSHIGRVHKLTIDDVTPADEADYS 615
++ G KL I DV DE Y+
Sbjct: 2335 YELVSDGLYRKLIISDVHAEDEDTYT 2360
Score = 100 bits (248), Expect = 1e-20
Identities = 81/269 (30%), Positives = 116/269 (43%), Gaps = 19/269 (7%)
Query: 347 GMLKRLKGMRRDEKKSTAFQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQMS 406
G+ KRLK M E +S +F+ L+ E A A W G+ + S
Sbjct: 2737 GITKRLKTMEVLEGESCSFE--------------CVLSHESASDPA--MWTVGGKTVG-S 2779
Query: 407 GSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCSTELFVKEPPVLITRPLEDQLVM 466
S++ G K L + + + +D V G L V+E P I +PLEDQ V
Sbjct: 2780 SSRFQATRQGRKYILVVREAAPSDAGEVVFSVRGLTSKASLIVRERPAAIIKPLEDQWVA 2839
Query: 467 VGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYA 526
G+ VE CE+S G V WLKD + + + KY +G L+I A L+DAG Y
Sbjct: 2840 PGEDVELRCELSRAGTPVHWLKDRKAIRKSQ--KYDVVCEGTMAMLVIRGASLKDAGEYT 2897
Query: 527 LCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVP 586
++ A L V+EK + + +L V K AVF C+ W K EL
Sbjct: 2898 CEVEASKSTASLHVEEKANCFTEELTNLQVEEKGTAVFTCKTEHPAATVTWRKGLLELRA 2957
Query: 587 DSRIKVSHIGRVHKLTIDDVTPADEADYS 615
+ + S G +LTI + AD Y+
Sbjct: 2958 SGKHQPSQEGLTLRLTISALEKADSDTYT 2986
Score = 99.0 bits (245), Expect = 3e-20
Identities = 78/274 (28%), Positives = 117/274 (42%), Gaps = 6/274 (2%)
Query: 365 FQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTIS 424
F++ L+ + Q +G L EL++ A V W K G ++Q +G + G L +
Sbjct: 3892 FREPLQ-SLQAEEGSTATLQCELSEPTATVVWSKGGLQLQANGRREP-RLQGCTAELVLQ 3949
Query: 425 QCSLADDAAYQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQV 484
D Y C G + S L V PV R L+ Q V G CE+S GA V
Sbjct: 3950 DLQREDTGEYTCTCGSQATSATLTVTAAPVRFLRELQHQEVDEGGTAHLCCELSRAGASV 4009
Query: 485 KWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKK 544
+W K ++L KY+ +DG L++ EDAG Y T Q++A L V+ +
Sbjct: 4010 EWRKGSLQLF--PCAKYQMVQDGAAAELLVRGVEQEDAGDYTCDTGHTQSMASLSVRVPR 4067
Query: 545 LEVYQSIADLMVGAKDQAVFKCEVSDENVRGV--WLKNGKELVPDSRIKVSHIGRVHKLT 602
+ + L D A C++SD V WLK G EL + ++ G +L
Sbjct: 4068 PKFKTRLQSLEQETGDIARLCCQLSDAESGAVVQWLKEGVELHAGPKYEMRSQGATRELL 4127
Query: 603 IDDVTPADEADYSFVPEGFACNLSAKLHFMEVKI 636
I + D +Y+ V G S ++ EV I
Sbjct: 4128 IHQLEAKDTGEYACVTGGQKTAASLRVTEPEVTI 4161
Score = 97.8 bits (242), Expect = 6e-20
Identities = 74/266 (27%), Positives = 114/266 (42%), Gaps = 9/266 (3%)
Query: 382 RLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGE 441
+L EL+D A V WLK+G+ + G KY ++ +R L + + D Y+CV G
Sbjct: 725 QLLAELSDQAAAVTWLKDGRTLS-PGPKYEVQASAGRRVLLVRDVARDDAGLYECVSRGG 783
Query: 442 KCSTELFVKEPPVLITRPLEDQLV--MVGQRVEFECEVSEEGAQVKWLKDGVELTREETF 499
+ + +L V+ + + + V + G +FECE SE V W KDG+EL
Sbjct: 784 RIAYQLSVQGLARFLHKDMAGSCVDAVAGGPAQFECETSEAHVHVHWYKDGMELGHSGE- 842
Query: 500 KYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKL---EVYQSIADLMV 556
++ + G RH L+ +D G Y+ L V E K+ + + L
Sbjct: 843 RFLQEDVGTRHRLVAATVTRQDEGTYSCRVGEDSVDFRLRVSEPKVVFAKEQLARRKLQA 902
Query: 557 GAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSF 616
A A CEV+ W K+GK+L S++ + G +L + AD +YS
Sbjct: 903 EAGASATLSCEVAQAQTEVTWYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEYSC 962
Query: 617 VPEGFACNLSAKLHFMEVKIDFVPRQ 642
E LS L E K+ F Q
Sbjct: 963 --EAGGQRLSFHLDVKEPKVVFAKDQ 986
Score = 92.8 bits (229), Expect = 2e-18
Identities = 98/377 (25%), Positives = 145/377 (38%), Gaps = 53/377 (14%)
Query: 395 KWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCSTELFVKEPPV 454
KWL G+ + +G E G L + + VG + S L V + PV
Sbjct: 2411 KWLL-GKTVLQAGGNVGLEQEGTVHRLMLRRTCSTMTGPVHFTVGKSRSSARLVVSDIPV 2469
Query: 455 LITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLII 514
++TRPLE + Q V C+ V+W KD L+ E FK +GQ L I
Sbjct: 2470 VLTRPLEPKTGRELQSVVLSCDFRPAPKAVQWYKDDTPLSPSEKFKMSL--EGQMAELRI 2527
Query: 515 NEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDENVR 574
M DAG Y + E+ V+ +++ V + D + A F CE+S E+
Sbjct: 2528 LRLMPADAGVYRCQAGSAHSSTEVTVEAREVTVTGPLQDAEATEEGWASFSCELSHEDEE 2587
Query: 575 GVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEV 634
W NG L DS ++SH GR H L + + AD + SA+L EV
Sbjct: 2588 VEWSLNGMPLYNDSFHEISHKGRRHTLVLKSIQRADAGIVR--ASSLKVSTSARL---EV 2642
Query: 635 KIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAP 694
++ P + L + D + L L +S DP V+W+K Q
Sbjct: 2643 RV-------KPVVFL----KALDDLSAEERGTLALQCEVS-DPEAHVVWRKDGVQ----- 2685
Query: 695 ARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVK 754
G SD++ F + T R + V ED G+YT
Sbjct: 2686 ----------LGPSDKYDF-------------LHTAGTRGL-VVHDVSPEDAGLYTC--- 2718
Query: 755 NPVGEDQVNLTVKVIDV 771
VG ++ V+V D+
Sbjct: 2719 -HVGSEETRARVRVHDL 2734
Score = 92.4 bits (228), Expect = 2e-18
Identities = 67/267 (25%), Positives = 116/267 (43%), Gaps = 11/267 (4%)
Query: 391 DAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCSTELFVK 450
D V W ++G +Q S K+ GA +LTIS L D G S L V+
Sbjct: 1926 DVAVVWFRDGALLQPS-EKFAISQSGASHSLTISDLVLEDAGQITVEAEGASSSAALRVR 1984
Query: 451 EPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKKDGQRH 510
E PVL + LE Q V V E E++ +++W ++ L + + +G RH
Sbjct: 1985 EAPVLFKKKLEPQTVEERSSVTLEVELTRPWPELRWTRNATALAPGKNVEIH--AEGARH 2042
Query: 511 HLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSD 570
L+++ D G + T + A+L V+ +++ + + + + + A + ++S
Sbjct: 2043 RLVLHNVGFADRGFFGCETPDDKTQAKLTVEMRQVRLVRGLQAVEAREQGTATMEVQLSH 2102
Query: 571 ENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLH 630
+V G W ++G ++ G +H LT+ + P D F EG + SA+L
Sbjct: 2103 ADVDGSWTRDGLRFQQGPTCHLAVRGPMHTLTLSGLRPEDSGLMVFKAEG--VHTSARLV 2160
Query: 631 FMEVKIDF------VPRQEPPKIHLDC 651
E+ + F V E K+ L+C
Sbjct: 2161 VTELPVSFSRPLQDVVTTEKEKVTLEC 2187
Score = 91.7 bits (226), Expect = 4e-18
Identities = 66/225 (29%), Positives = 95/225 (42%), Gaps = 5/225 (2%)
Query: 392 AEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCSTELFVKE 451
A V+W K G E G +Y G + L I S+AD Y CV G E+ S L V+
Sbjct: 3829 APVEWRK-GSETLRGGDRYSLRQDGTRCELQIHGLSVADTGEYSCVCGQERTSATLTVRA 3887
Query: 452 PPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKKDGQRHH 511
P + PL+ G +CE+SE A V W K G++L + R + G
Sbjct: 3888 PQPVFREPLQSLQAEEGSTATLQCELSEPTATVVWSKGGLQLQANGRREPRLQ--GCTAE 3945
Query: 512 LIINEAMLEDAGHYALCTSGGQAL-AELIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSD 570
L++ + ED G Y CT G QA A L V + + + V A CE+S
Sbjct: 3946 LVLQDLQREDTGEYT-CTCGSQATSATLTVTAAPVRFLRELQHQEVDEGGTAHLCCELSR 4004
Query: 571 ENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYS 615
W K +L P ++ ++ G +L + V D DY+
Sbjct: 4005 AGASVEWRKGSLQLFPCAKYQMVQDGAAAELLVRGVEQEDAGDYT 4049
Score = 88.6 bits (218), Expect = 3e-17
Identities = 112/508 (22%), Positives = 186/508 (36%), Gaps = 63/508 (12%)
Query: 394 VKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCSTELFVKEPP 453
V+W G +Q + + G TL + + D +G S +L V+ P
Sbjct: 4190 VQWCLQGLPLQSNEVTEVAVRDGRIHTLRLKGVTPEDAGTVSFHLGNHASSAQLTVRAPE 4249
Query: 454 VLITRPLEDQLVMVGQRVEFECEVSE-EGAQVKWLKDGVELTREETFKYRFKKDGQRHHL 512
V I PL+D + GQ F+C +S G + +W GV L E ++ G H L
Sbjct: 4250 VTILEPLQDVQLSEGQDASFQCRLSRASGQEARWALGGVPLQANEMNDITVEQ-GTLHLL 4308
Query: 513 IINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDEN 572
+++ LEDAG + + A+L V K V + + ++ +A+F+C++S
Sbjct: 4309 TLHKVTLEDAGTVSFHVGTCSSEAQLKVTAKNT-VVRGLENVEALEGGEALFECQLSQPE 4367
Query: 573 VRG-VWLKNGKELVPDSRIKVSHI--GRVHKLTIDDVTPADEADYSFVPEGFACNLSAKL 629
V WL + + + +V G H L + ++ P D +F+ + +
Sbjct: 4368 VAAHTWLLDDEPVHTSENAEVVFFENGLRHLLLLKNLRPQDSCRVTFLAGDMVTSAFLTV 4427
Query: 630 HFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPIS-GDPAPTVIWQKAIT 688
++I EP K V AG + +S P W
Sbjct: 4428 RGWRLEI-----LEPLK-----------NAAVRAGAQACFTCTLSEAVPVGEASWYI--- 4468
Query: 689 QGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGV 748
N A +P D +W V + A+ G
Sbjct: 4469 --NGAAVQP---------DDSDWT--------------VTADGSHHALLLRSAQPHHAGE 4503
Query: 749 YTVTVKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYIL 808
T ++ V ++ V+ +PD P ++ + T+ W P DGG + GY +
Sbjct: 4504 VTFACRDAVASARLT----VLGLPDPPEDAEVVARSSHTVTLSWAAPMSDGGGGLCGYRV 4559
Query: 809 ERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQ------ 862
E K+ + +W RL +L+ + G Y RV AV +G P Q
Sbjct: 4560 EVKEGATGQW-RLCHELVPGPECVVDGLAPGETYRFRVAAVGPVGAGEPVHLPQTVRLAE 4618
Query: 863 PFMPIGP-PSEPTHLAVEDVSDTTVSLK 889
P P+ P PS P V D ++ L+
Sbjct: 4619 PPKPVPPQPSAPESRQVAAGEDVSLELE 4646
Score = 87.4 bits (215), Expect = 8e-17
Identities = 139/653 (21%), Positives = 227/653 (34%), Gaps = 86/653 (13%)
Query: 7 KPVSAFSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYG-LATEGTRHT 65
KPV F K + + E V W++ G + S+KY L T GTR
Sbjct: 2645 KPV-VFLKALDDLSAEERGTLALQCEVSDPEAHVVWRKDGVQLGPSDKYDFLHTAGTRG- 2702
Query: 66 LTVREVGPADQGSYAVIAGSSKVKFDLKVIEAEKAEPMLAPAPAPAEATGAPGEAPAPAA 125
L V +V P D G Y GS + + ++V + E E
Sbjct: 2703 LVVHDVSPEDAGLYTCHVGSEETRARVRVHDLHVGITKRLKTMEVLEGESCSFECVLSHE 2762
Query: 126 ELGESAPSPKGSSSAALNGPTPGAPDDPIGLFVMR---PQD-GEVTVG-----GSITFSA 176
+ A G + + + V+R P D GEV +
Sbjct: 2763 SASDPAMWTVGGKTVGSSSRFQATRQGRKYILVVREAAPSDAGEVVFSVRGLTSKASLIV 2822
Query: 177 RVAGASLLKPPVVKWFK-GKWVDLSSKVGQH------------LQLHDSYDRASKVYLFE 223
R A+++KP +W G+ V+L ++ + ++ YD + +
Sbjct: 2823 RERPAAIIKPLEDQWVAPGEDVELRCELSRAGTPVHWLKDRKAIRKSQKYDVVCEGTMAM 2882
Query: 224 LHITDAQPAFTGSYRCEVSTKDKFDCSNFNLTVHEAMGTGDLDLLSAFRRTSLAGGGRRI 283
L I A G Y CEV S +L V E +L +
Sbjct: 2883 LVIRGASLKDAGEYTCEVEASK----STASLHVEEKANCFTEELTNL------------- 2925
Query: 284 SDSHEDTGILDFSSLLKKRDSFRTPRDSKLEAPAEEDVWE--ILRQAPPSEYERIAFQYG 341
E+ G F+ K E PA W +L +++ Q G
Sbjct: 2926 --QVEEKGTAVFTC--------------KTEHPAATVTWRKGLLELRASGKHQ--PSQEG 2967
Query: 342 VTDLRGMLKRLKGMRRDEKKSTAFQKKLEPAYQVSKGHKIRLTVELADHDAE-------- 393
+T LR + L+ D Q + A + +G ++ + +L D D +
Sbjct: 2968 LT-LRLTISALEKADSDTYTCDIGQAQSR-AQLLVQGRRVHIIEDLEDVDVQEGSSATFR 3025
Query: 394 ----------VKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKC 443
V W + + + I G LT+ Q +L D G ++
Sbjct: 3026 CRISPANYEPVHWFLDKTPLHANELNEIDAQPGGYHVLTLRQLALKDSGTIYFEAGDQRA 3085
Query: 444 STELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRF 503
S L V E P + +R L D + G+ + CE S V W KDG L + + +
Sbjct: 3086 SAALRVTEKPSVFSRELTDATITEGEDLTLVCETSTCDIPVCWTKDGKTL--RGSARCQL 3143
Query: 504 KKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELI-VQEKKLEVYQSIADLMVGAKDQA 562
+G R L+I A L+D+G Y C +GG + ++ V + + +++ DL V A
Sbjct: 3144 SHEGHRAQLLITGATLQDSGRYK-CEAGGACSSSIVRVHARPVRFQEALKDLEVLEGGAA 3202
Query: 563 VFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYS 615
+C +S W L P + + G + +L + ++ P D YS
Sbjct: 3203 TLRCVLSSVAAPVKWCYGNNVLRPGDKYSLRQEGAMLELVVRNLRPQDSGRYS 3255
Score = 85.9 bits (211), Expect = 2e-16
Identities = 75/278 (26%), Positives = 112/278 (40%), Gaps = 4/278 (1%)
Query: 359 EKKSTAFQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAK 418
E+K+ F ++L KG + T + A V W K E++ SG K+ G
Sbjct: 2912 EEKANCFTEELTNLQVEEKGTAV-FTCKTEHPAATVTWRKGLLELRASG-KHQPSQEGLT 2969
Query: 419 RTLTISQCSLADDAAYQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVS 478
LTIS AD Y C +G + +L V+ V I LED V G F C +S
Sbjct: 2970 LRLTISALEKADSDTYTCDIGQAQSRAQLLVQGRRVHIIEDLEDVDVQEGSSATFRCRIS 3029
Query: 479 EEGAQ-VKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAE 537
+ V W D L E + + G H L + + L+D+G +A A
Sbjct: 3030 PANYEPVHWFLDKTPLHANELNEIDAQPGGY-HVLTLRQLALKDSGTIYFEAGDQRASAA 3088
Query: 538 LIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGR 597
L V EK + + D + + CE S ++ W K+GK L +R ++SH G
Sbjct: 3089 LRVTEKPSVFSRELTDATITEGEDLTLVCETSTCDIPVCWTKDGKTLRGSARCQLSHEGH 3148
Query: 598 VHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVK 635
+L I T D Y G + ++H V+
Sbjct: 3149 RAQLLITGATLQDSGRYKCEAGGACSSSIVRVHARPVR 3186
Score = 84.3 bits (207), Expect = 7e-16
Identities = 64/250 (25%), Positives = 104/250 (41%), Gaps = 4/250 (1%)
Query: 365 FQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTIS 424
F+KKLEP V + + L VEL E++W +N + G + GA+ L +
Sbjct: 1990 FKKKLEPQ-TVEERSSVTLEVELTRPWPELRWTRNATALA-PGKNVEIHAEGARHRLVLH 2047
Query: 425 QCSLADDAAYQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQV 484
AD + C +K +L V+ V + R L+ E ++S
Sbjct: 2048 NVGFADRGFFGCETPDDKTQAKLTVEMRQVRLVRGLQAVEAREQGTATMEVQLSHADVDG 2107
Query: 485 KWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKK 544
W +DG+ + T + G H L ++ ED+G G A L+V E
Sbjct: 2108 SWTRDGLRFQQGPTCHLAVR--GPMHTLTLSGLRPEDSGLMVFKAEGVHTSARLVVTELP 2165
Query: 545 LEVYQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTID 604
+ + + D++ K++ +CE+S NV WLK+G EL + ++ G LTI
Sbjct: 2166 VSFSRPLQDVVTTEKEKVTLECELSRPNVDVRWLKDGVELRAGKTMAIAAQGACRSLTIY 2225
Query: 605 DVTPADEADY 614
AD+ Y
Sbjct: 2226 RCEFADQGVY 2235
Score = 83.2 bits (204), Expect = 1e-15
Identities = 64/237 (27%), Positives = 99/237 (41%), Gaps = 4/237 (1%)
Query: 379 HKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVV 438
H+ L +++ A+V+W K QE+Q G KY S G R L IS D+ Y C
Sbjct: 2305 HRGVLECQVSRASAQVRWFKGSQELQ-PGPKYELVSDGLYRKLIISDVHAEDEDTYTCDA 2363
Query: 439 GGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQ-VKWLKDGVELTREE 497
G K S + FV+E + I R L+D VM FECE S + KWL L +
Sbjct: 2364 GDVKTSAQFFVEEQSITIVRGLQDVTVMEPAPAWFECETSIPSVRPPKWLLGKTVL--QA 2421
Query: 498 TFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVG 557
+++G H L++ G ++ A L+V + + + + +
Sbjct: 2422 GGNVGLEQEGTVHRLMLRRTCSTMTGPVHFTVGKSRSSARLVVSDIPVVLTRPLEPKTGR 2481
Query: 558 AKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADY 614
V C+ W K+ L P + K+S G++ +L I + PAD Y
Sbjct: 2482 ELQSVVLSCDFRPAPKAVQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADAGVY 2538
Score = 82.8 bits (203), Expect = 2e-15
Identities = 62/242 (25%), Positives = 105/242 (43%), Gaps = 5/242 (2%)
Query: 374 QVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAA 433
+ ++G L EL+ A V+W K G E G ++ G++ L I ++ D
Sbjct: 3724 EATEGDTATLWCELSKA-APVEWRK-GHETLRDGDRHSLRQDGSRCELQIRGLAVVDAGE 3781
Query: 434 YQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVEL 493
Y CV G E+ S L V+ P +++Q G +CE+S + A V+W K L
Sbjct: 3782 YSCVCGQERTSATLTVRALPARFIEDVKNQEAREGATAVLQCELS-KAAPVEWRKGSETL 3840
Query: 494 TREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIAD 553
+ +Y ++DG R L I+ + D G Y+ + A L V+ + + +
Sbjct: 3841 RGGD--RYSLRQDGTRCELQIHGLSVADTGEYSCVCGQERTSATLTVRAPQPVFREPLQS 3898
Query: 554 LMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEAD 613
L A +CE+S+ VW K G +L + R + G +L + D+ D +
Sbjct: 3899 LQAEEGSTATLQCELSEPTATVVWSKGGLQLQANGRREPRLQGCTAELVLQDLQREDTGE 3958
Query: 614 YS 615
Y+
Sbjct: 3959 YT 3960
Score = 80.9 bits (198), Expect = 7e-15
Identities = 67/249 (26%), Positives = 105/249 (42%), Gaps = 10/249 (4%)
Query: 375 VSKGHKIRLTVELA-DHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAA 433
V++G RL+ + + E W K+GQ + ++E L I C +D
Sbjct: 249 VTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGL 308
Query: 434 YQC----VVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKD 489
Y C +VG S + V+EP V + L+D V + F CEV + + W K+
Sbjct: 309 YTCTASNLVGQTYSSVLVVVREPAVPFKKRLQDLEVREKESATFLCEVPQPSTEAAWFKE 368
Query: 490 GVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCT-SGGQALAELIVQEKKLEVY 548
L + KY +++G L + +D Y T G + +AEL VQ L
Sbjct: 369 ETRLW--ASAKYGIEEEGTERRLTVRNVSADDDAVYICETPEGSRTVAELAVQGNLLRKL 426
Query: 549 QSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTP 608
+ VG D A+F E++ WL+N +E+V R+ +S G H LTI
Sbjct: 427 PRKTAVRVG--DTAMFCVELAVPVGPVHWLRNQEEVVAGGRVAISAEGTRHTLTISQCCL 484
Query: 609 ADEADYSFV 617
D +F+
Sbjct: 485 EDVGQVAFM 493
Score = 79.7 bits (195), Expect = 2e-14
Identities = 139/619 (22%), Positives = 230/619 (37%), Gaps = 121/619 (19%)
Query: 465 VMVGQRVEFECEVS-EEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLI-INEAMLEDA 522
V G+ C V+ E + W KDG +T E ++ +D Q + ++ I D
Sbjct: 249 VTEGKHARLSCYVTGEPKPETVWKKDGQLVT--EGRRHVVYEDAQENFVLKILFCKQSDR 306
Query: 523 GHYALCTSG--GQALAEL--IVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDENVRGVWL 578
G Y S GQ + + +V+E + + + DL V K+ A F CEV + W
Sbjct: 307 GLYTCTASNLVGQTYSSVLVVVREPAVPFKKRLQDLEVREKESATFLCEVPQPSTEAAWF 366
Query: 579 KNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSF-VPEGFACNLSAKLHFMEVKID 637
K L ++ + G +LT+ +V+ D+A Y PEG S + + V+ +
Sbjct: 367 KEETRLWASAKYGIEEEGTERRLTVRNVSADDDAVYICETPEG-----SRTVAELAVQGN 421
Query: 638 FVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARP 697
+ R+ P K + R+ DT + + L VP+ P + Q+ + G
Sbjct: 422 LL-RKLPRKTAV----RVGDTAMFC----VELAVPVG--PVHWLRNQEEVVAG------- 463
Query: 698 APDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPV 757
GRV + R T+ ED G +
Sbjct: 464 -------------------------GRVAISAEGTRHTLTISQCCLEDVGQVAFMAGDCQ 498
Query: 758 GEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPIL--GYILERKKKKS 815
Q ++ P P + E S + W PP + G +P+ GY++E+KK +
Sbjct: 499 TSTQFCVSAPRKPPLQPPVDPVVKARMESSVILSWSPPPH-GERPVTIDGYLVEKKKLGT 557
Query: 816 YRWMRLN-FDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPT 874
Y W+R + + + + E ++ RV A+N+ G S P++
Sbjct: 558 YTWIRCHEAEWVATPELTVADVAEEGNFQFRVSALNSFGQS-------PYLEF---PGTV 607
Query: 875 HLAVEDVSDTTVSLKWRPPERVGA--GGLDGYSVEYCPEGCSEWVAALQGL--------- 923
HLA + T P + V A GG +SV+ EW Q L
Sbjct: 608 HLAPKLAVRT-------PLKAVQAVEGGEVTFSVDLTVASAGEWFLDGQALKASSVYEIH 660
Query: 924 ---TEHTSILVKDLPT---GARLLF-------RVRAHNMAGPGAPVTTTEPVTVQEILQR 970
T HT + ++++P GA+L F +R A PG +E+L R
Sbjct: 661 CDRTRHT-LTIREVPASLHGAQLKFVANGIESSIRMEVRAAPGLTANKPPAAAAREVLAR 719
Query: 971 PRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLA-GEEVSIRNSPTDTI 1029
+ E LL + VTW K+G+ L+ G + ++ S +
Sbjct: 720 ----------------LHEEAQLLAELSDQ-AAAVTWLKDGRTLSPGPKYEVQASAGRRV 762
Query: 1030 LFIRAARRVHSGTYQVTVR 1048
L +R R +G Y+ R
Sbjct: 763 LLVRDVARDDAGLYECVSR 781
Score = 78.2 bits (191), Expect = 5e-14
Identities = 143/648 (22%), Positives = 235/648 (36%), Gaps = 64/648 (9%)
Query: 6 KKPVSAFSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHT 65
+ P F + +S++ GS A + E V W +GG + A+ + +G
Sbjct: 3886 RAPQPVFREPLQSLQAEEGSTATLQCELSEPTATVVWSKGGLQLQANGRREPRLQGCTAE 3945
Query: 66 LTVREVGPADQGSYAVIAGSSKVKFDLKVIEAEKAEPMLAPAPAPAEATGAPGEAPAPAA 125
L ++++ D G Y GS L V A L G +
Sbjct: 3946 LVLQDLQREDTGEYTCTCGSQATSATLTVTAAPVR--FLRELQHQEVDEGGTAHLCCELS 4003
Query: 126 ELGESAPSPKGSSS----AALNGPTPGAPDDPIGLFVMRPQDGEVTVGGSITFSARVAGA 181
G S KGS A GA + + V + G+ T T S
Sbjct: 4004 RAGASVEWRKGSLQLFPCAKYQMVQDGAAAELLVRGVEQEDAGDYTCDTGHTQSMASLSV 4063
Query: 182 SLLKPPVVKWFKGKWVDLSSKVGQHL----QLHDSYDRASKVYLFELHITDAQPAFTGSY 237
+ +P FK + L + G QL D+ A +L E A P +
Sbjct: 4064 RVPRPK----FKTRLQSLEQETGDIARLCCQLSDAESGAVVQWLKEGVELHAGPKY--EM 4117
Query: 238 RCEVSTKDKFDCSNFNLTVH--EAMGTGDLDLLSAFRRTSLAGGGRRISDSHEDT--GIL 293
R + +T++ L +H EA TG+ ++ ++T+ + R+++ G++
Sbjct: 4118 RSQGATRE--------LLIHQLEAKDTGEYACVTGGQKTAAS---LRVTEPEVTIVRGLV 4166
Query: 294 DFSSLLKKRDSFRTPRDSKLEAPAEEDVWEILRQAPPSEYERIAFQYGVTDLRGMLKRLK 353
D + F ++ V L+ P E + V D R RLK
Sbjct: 4167 DAEVTADEDVEF----SCEVSRAGATGVQWCLQGLPLQSNE--VTEVAVRDGRIHTLRLK 4220
Query: 354 GMRRDEKKSTAFQKK-----------------LEPAY--QVSKGHKIRLTVELADHDA-E 393
G+ ++ + +F LEP Q+S+G L+ E
Sbjct: 4221 GVTPEDAGTVSFHLGNHASSAQLTVRAPEVTILEPLQDVQLSEGQDASFQCRLSRASGQE 4280
Query: 394 VKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCSTELFVKEPP 453
+W G +Q + I G LT+ + +L D VG CS+E +K
Sbjct: 4281 ARWALGGVPLQANEMNDITVEQGTLHLLTLHKVTLEDAGTVSFHVG--TCSSEAQLKVTA 4338
Query: 454 V-LITRPLEDQLVMVGQRVEFECEVSE-EGAQVKWLKDGVELTREETFKYRFKKDGQRHH 511
+ R LE+ + G FEC++S+ E A WL D + E + F ++G RH
Sbjct: 4339 KNTVVRGLENVEALEGGEALFECQLSQPEVAAHTWLLDDEPVHTSENAEVVFFENGLRHL 4398
Query: 512 LIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDE 571
L++ +D+ A L V+ +LE+ + + + V A QA F C +S+
Sbjct: 4399 LLLKNLRPQDSCRVTFLAGDMVTSAFLTVRGWRLEILEPLKNAAVRAGAQACFTCTLSEA 4458
Query: 572 NVRG--VWLKNGKELVP-DSRIKVSHIGRVHKLTIDDVTPADEADYSF 616
G W NG + P DS V+ G H L + P + +F
Sbjct: 4459 VPVGEASWYINGAAVQPDDSDWTVTADGSHHALLLRSAQPHHAGEVTF 4506
Score = 76.6 bits (187), Expect = 1e-13
Identities = 153/669 (22%), Positives = 246/669 (36%), Gaps = 122/669 (18%)
Query: 6 KKPVSAFSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHT 65
++ + F+++ +++V AVF +TE V W++G ++ AS K+ + EG
Sbjct: 2912 EEKANCFTEELTNLQVEEKGTAVFTCKTEHPAATVTWRKGLLELRASGKHQPSQEGLTLR 2971
Query: 66 LTVREVGPADQGSYAVIAGSSKVKF----------------DLKVIEAEKAEPMLAPAPA 109
LT+ + AD +Y G ++ + D+ V E A +PA
Sbjct: 2972 LTISALEKADSDTYTCDIGQAQSRAQLLVQGRRVHIIEDLEDVDVQEGSSATFRCRISPA 3031
Query: 110 PAEATG-APGEAPAPAAELGESAPSPKG------------------------SSSAALNG 144
E + P A EL E P G +SAAL
Sbjct: 3032 NYEPVHWFLDKTPLHANELNEIDAQPGGYHVLTLRQLALKDSGTIYFEAGDQRASAALR- 3090
Query: 145 PTPGAPDDPIGLFVMRPQDGEVTVGGSITFSARVAGASLLKPPVVKWFKGKWVDLSSKVG 204
+ P +F D +T G +T V S PV GK + S++
Sbjct: 3091 ----VTEKP-SVFSRELTDATITEGEDLTL---VCETSTCDIPVCWTKDGKTLRGSARC- 3141
Query: 205 QHLQLHDSYDRASKVYLFELHITDAQPAFTGSYRCEVSTKDKFDCSNFNLTVH------- 257
QL RA +L IT A +G Y+CE CS+ + VH
Sbjct: 3142 ---QLSHEGHRA------QLLITGATLQDSGRYKCEAGGA----CSSSIVRVHARPVRFQ 3188
Query: 258 EAMGTGDLDLL---SAFRRTSLAGGGRRISDSHEDTGILDFSSLLKKRDSFRTPRDSKLE 314
EA+ DL++L +A R L+ + + + ++L+ D + ++ +
Sbjct: 3189 EALK--DLEVLEGGAATLRCVLSSVAAPVKWCYGN-------NVLRPGDKYSLRQEGAM- 3238
Query: 315 APAEEDVWEILRQAPPSEYERIAFQYGVTDLRGMLKRLKGMRRDEKKSTAFQKKLEPAYQ 374
+ ++R P + R + +G D+ S PA
Sbjct: 3239 ------LELVVRNLRPQDSGRYSCSFG----------------DQTTSATLTVTALPAQF 3276
Query: 375 VSK--------GHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQC 426
+ K G L EL+ A V+W K G E G +Y GA L I
Sbjct: 3277 IGKLRNKEATEGATATLRCELSKA-APVEWRK-GSETLRDGDRYCLRQDGAMCELQIRGL 3334
Query: 427 SLADDAAYQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKW 486
++ D A Y CV G E+ S L ++ P L Q + G CE+S + A V+W
Sbjct: 3335 AMVDAAEYSCVCGEERTSASLTIRPMPAHFIGRLRHQESIEGATATLRCELS-KAAPVEW 3393
Query: 487 LKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLE 546
K G E R+ ++ ++DG L I + DAG Y+ + A L V+ +
Sbjct: 3394 RK-GRESLRDGD-RHSLRQDGAVCELQICGLAVADAGEYSCVCGEERTSATLTVKALPAK 3451
Query: 547 VYQSIADLMVGAKDQAVFKCEVSDENVRGV-WLKNGKELVPDSRIKVSHIGRVHKLTIDD 605
+ + + A+ CE+S V V W K + L R + G +L I
Sbjct: 3452 FTEGLRNEEAVEGATAMLWCELS--KVAPVEWRKGPENLRDGDRYILRQEGTRCELQICG 3509
Query: 606 VTPADEADY 614
+ AD +Y
Sbjct: 3510 LAMADAGEY 3518
Score = 76.6 bits (187), Expect = 1e-13
Identities = 65/226 (28%), Positives = 96/226 (42%), Gaps = 5/226 (2%)
Query: 392 AEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCSTELFVKE 451
A V+W K G E G +Y G K L I ++AD Y CV G E+ S L V+
Sbjct: 3565 APVEWRK-GSETLRDGDRYSLRQDGTKCELQIRGLAMADTGEYSCVCGQERTSAMLTVRA 3623
Query: 452 PPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKKDGQRHH 511
P+ T L ++ G CE+S+ A V+W K G E R+ ++ ++DG R
Sbjct: 3624 LPIKFTEGLRNEEATEGATAVLRCELSKM-APVEWWK-GHETLRDGD-RHSLRQDGARCE 3680
Query: 512 LIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDE 571
L I + EDAG Y + A L V+ + + + + D A CE+S +
Sbjct: 3681 LQIRGLVAEDAGEYLCMCGKERTSAMLTVRAMPSKFIEGLRNEEATEGDTATLWCELS-K 3739
Query: 572 NVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFV 617
W K + L R + G +L I + D +YS V
Sbjct: 3740 AAPVEWRKGHETLRDGDRHSLRQDGSRCELQIRGLAVVDAGEYSCV 3785
Score = 70.1 bits (170), Expect = 1e-11
Identities = 58/223 (26%), Positives = 95/223 (42%), Gaps = 5/223 (2%)
Query: 392 AEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCSTELFVKE 451
A V+W K G E G +YI G + L I ++AD Y CV G E+ S L ++
Sbjct: 3477 APVEWRK-GPENLRDGDRYILRQEGTRCELQICGLAMADAGEYLCVCGQERTSATLTIRA 3535
Query: 452 PPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKKDGQRHH 511
P +++Q G +CE++ A V+W K G E R+ +Y ++DG +
Sbjct: 3536 LPARFIEDVKNQEAREGATAVLQCELN-SAAPVEWRK-GSETLRDGD-RYSLRQDGTKCE 3592
Query: 512 LIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDE 571
L I + D G Y+ + A L V+ ++ + + + AV +CE+S +
Sbjct: 3593 LQIRGLAMADTGEYSCVCGQERTSAMLTVRALPIKFTEGLRNEEATEGATAVLRCELS-K 3651
Query: 572 NVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADY 614
W K + L R + G +L I + D +Y
Sbjct: 3652 MAPVEWWKGHETLRDGDRHSLRQDGARCELQIRGLVAEDAGEY 3694
Score = 68.2 bits (165), Expect = 5e-11
Identities = 126/582 (21%), Positives = 203/582 (34%), Gaps = 81/582 (13%)
Query: 1 MPEPGKKPVSAFSKKPRSVEVAAGSPAVFEAE-TERAGVKVRWQRGGSDISASNKYGLAT 59
M +P F +P++ V+ G A + +V W++ ++A ++ LA
Sbjct: 1 MDQPQFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQ 60
Query: 60 EGTRHTLTVREVGPADQGSYAVIA----GSSKVKFDLKVIEAEKAEPMLAP--APAPAEA 113
+G + LT+ ++ D G Y A G + L+V +AE A AP P
Sbjct: 61 DGDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQV-DAEAACAEQAPHFLLRPTSI 119
Query: 114 TGAPGEAPAPAAELGESAPSPKGSSSAALNGPTPGAPDDP------------IGLFVMRP 161
G +G S P+ + S + +G G PD P + + RP
Sbjct: 120 RVREGSEATFRCRVGGS---PRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARP 176
Query: 162 QDGEV-TVGGSITFSARVAGASLLKPPVVKWFKGKWVDLSSKVGQHLQLHDSYDRASKVY 220
+DG V A A A+L+ + ++ + HLQ RA
Sbjct: 177 RDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRREAMRAEGA- 235
Query: 221 LFELHITDAQPAFTGSYRCEVSTKD--KFDCSNFNLTVHEAMGTGDLDLLSAFRRTSLAG 278
A P TG+ C V+ + C E + D L++ RR
Sbjct: 236 -------PASPPSTGTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRR----- 283
Query: 279 GGRRISDSHEDTGILDFSSLLKKRDSFRTPRDSKLEAPAEEDVWEILRQAPPSEYERIAF 338
+ + ++ +L + T S L V ++R+ + F
Sbjct: 284 --HVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVREPA------VPF 335
Query: 339 QYGVTDLRGMLKRLKGMRRDEKKSTAFQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLK 398
+ KRL+ + EK+S F E+ E W K
Sbjct: 336 K----------KRLQDLEVREKESATF------------------LCEVPQPSTEAAWFK 367
Query: 399 NGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVG-GEKCSTELFVKEPPVLIT 457
+ S +KY E G +R LT+ S DDA Y C G + EL V+ L+
Sbjct: 368 EETRLWAS-AKYGIEEEGTERRLTVRNVSADDDAVYICETPEGSRTVAELAVQGN--LLR 424
Query: 458 RPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEA 517
+ V VG F E++ V WL++ E+ + +G RH L I++
Sbjct: 425 KLPRKTAVRVGDTAMFCVELAVPVGPVHWLRNQEEVVAGG--RVAISAEGTRHTLTISQC 482
Query: 518 MLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAK 559
LED G A Q + V + Q D +V A+
Sbjct: 483 CLEDVGQVAFMAGDCQTSTQFCVSAPRKPPLQPPVDPVVKAR 524
Score = 68.2 bits (165), Expect = 5e-11
Identities = 73/294 (24%), Positives = 116/294 (39%), Gaps = 22/294 (7%)
Query: 392 AEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCSTELFVKE 451
A V+W K G E G ++ GA+ L I D Y C+ G E+ S L V+
Sbjct: 3653 APVEWWK-GHETLRDGDRHSLRQDGARCELQIRGLVAEDAGEYLCMCGKERTSAMLTVRA 3711
Query: 452 PPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKKDGQRHH 511
P L ++ G CE+S+ A V+W K G E R+ ++ ++DG R
Sbjct: 3712 MPSKFIEGLRNEEATEGDTATLWCELSK-AAPVEWRK-GHETLRDGD-RHSLRQDGSRCE 3768
Query: 512 LIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDE 571
L I + DAG Y+ + A L V+ + + + AV +CE+S +
Sbjct: 3769 LQIRGLAVVDAGEYSCVCGQERTSATLTVRALPARFIEDVKNQEAREGATAVLQCELS-K 3827
Query: 572 NVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHF 631
W K + L R + G +L I ++ AD +YS V C
Sbjct: 3828 AAPVEWRKGSETLRGGDRYSLRQDGTRCELQIHGLSVADTGEYSCV-----CGQERTSAT 3882
Query: 632 MEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQK 685
+ V+ +EP + ++ G+ L +S +P TV+W K
Sbjct: 3883 LTVRAPQPVFREPLQ-----------SLQAEEGSTATLQCELS-EPTATVVWSK 3924
Score = 62.8 bits (151), Expect = 2e-09
Identities = 66/261 (25%), Positives = 98/261 (37%), Gaps = 6/261 (2%)
Query: 357 RDEKKSTAFQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIG 416
R + FQ+ L+ +V +G L L+ A VKW G + G KY G
Sbjct: 3179 RVHARPVRFQEALKDL-EVLEGGAATLRCVLSSVAAPVKWCY-GNNVLRPGDKYSLRQEG 3236
Query: 417 AKRTLTISQCSLADDAAYQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECE 476
A L + D Y C G + S L V P L ++ G CE
Sbjct: 3237 AMLELVVRNLRPQDSGRYSCSFGDQTTSATLTVTALPAQFIGKLRNKEATEGATATLRCE 3296
Query: 477 VSEEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALA 536
+S + A V+W K G E R+ +Y ++DG L I + DA Y+ + A
Sbjct: 3297 LS-KAAPVEWRK-GSETLRDGD-RYCLRQDGAMCELQIRGLAMVDAAEYSCVCGEERTSA 3353
Query: 537 ELIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIG 596
L ++ + A +CE+S + W K + L R + G
Sbjct: 3354 SLTIRPMPAHFIGRLRHQESIEGATATLRCELS-KAAPVEWRKGRESLRDGDRHSLRQDG 3412
Query: 597 RVHKLTIDDVTPADEADYSFV 617
V +L I + AD +YS V
Sbjct: 3413 AVCELQICGLAVADAGEYSCV 3433
Score = 60.5 bits (145), Expect = 1e-08
Identities = 62/224 (27%), Positives = 84/224 (37%), Gaps = 19/224 (8%)
Query: 1030 LFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPP 1089
L +R+A+ H+G R + A+ L V+ P PP+D V V L W P
Sbjct: 4491 LLLRSAQPHHAGEVTFACR----DAVASARLTVLGLPDPPEDAEVVARSSHTVTLSWAAP 4546
Query: 1090 QDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSD 1149
G L GY V+ + T +W E CVV L G Y FRV + VG
Sbjct: 4547 MSDGGGGLCGYRVEVKEGATGQWRLCHELVPGPECVVDGLAPGETYRFRVAAVGPVG--- 4603
Query: 1150 RAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPK 1209
EPV +P+ EPP P +R V AG L V +
Sbjct: 4604 ----AGEPVHLPQTVRLAEPP-------KPVPPQPSAPESRQVAAGEDVSLELEV-VAEA 4651
Query: 1210 PKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVC 1253
++ W K + RF + S+ L I+ D G Y C
Sbjct: 4652 GEVIWHKGMERIQPGGRFEVVSQGRQQMLVIKGFTAEDQGEYHC 4695
Score = 58.2 bits (139), Expect = 5e-08
Identities = 40/112 (35%), Positives = 51/112 (45%), Gaps = 4/112 (3%)
Query: 1161 PRPGITYEP-PNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGL 1219
P P + EP P+ D AP F L N+ V GY C V G P P + WFK+G
Sbjct: 5107 PAPVVPPEPLPSLLTSD--AAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGK 5164
Query: 1220 DLGEDARFRM-FSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
L ED + + +QG L I P D G+Y C A N G + + L V
Sbjct: 5165 LLEEDDHYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRV 5216
Score = 56.6 bits (135), Expect = 1e-07
Identities = 30/95 (31%), Positives = 44/95 (46%), Gaps = 2/95 (2%)
Query: 1181 PSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFS--KQGVLTL 1238
P F + + G A C + G+P P+I W+K+G L +F+ S + G+L L
Sbjct: 6108 PRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVL 6167
Query: 1239 EIRKPCPFDGGIYVCRATNLQGEARCECRLEVRVP 1273
IR D G+Y C N G AR L ++ P
Sbjct: 6168 VIRAASKEDLGLYECELVNRLGSARASAELRIQSP 6202
Score = 54.7 bits (130), Expect = 6e-07
Identities = 35/94 (37%), Positives = 44/94 (46%)
Query: 1177 FSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVL 1236
FS AP F V G A L C + G+P P++SW K+ + ARFR+ +
Sbjct: 6 FSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLY 65
Query: 1237 TLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
L I D G YVCRA N GEA L+V
Sbjct: 66 RLTILDLALGDSGQYVCRARNAIGEAFAAVGLQV 99
Score = 53.5 bits (127), Expect = 1e-06
Identities = 47/192 (24%), Positives = 78/192 (40%), Gaps = 20/192 (10%)
Query: 394 VKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGE--KCST--ELFV 449
+ W K+G+ +Q+ + E L + + D Y C CST ++ V
Sbjct: 6045 ISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMCFAASAAGNCSTLGKILV 6104
Query: 450 KEPPVLITRPLEDQLVMVGQRVEFECEVSEEGA---QVKWLKDGVELTREETFKYRFKKD 506
+ PP + + V G+ +F C + EGA Q++W KDG LT F+ +
Sbjct: 6105 QVPPRFVNKVRASPFV-EGEDAQFTCTI--EGAPYPQIRWYKDGALLTTGNKFQTLSEPR 6161
Query: 507 GQRHHLIINEAMLEDAGHYAL----CTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQA 562
L+I A ED G Y +A AEL +Q L+ + ++Q
Sbjct: 6162 SGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQC------HREQL 6215
Query: 563 VFKCEVSDENVR 574
V EV+++ +
Sbjct: 6216 VAAVEVTEQETK 6227
Score = 51.6 bits (122), Expect = 5e-06
Identities = 36/94 (38%), Positives = 42/94 (44%), Gaps = 2/94 (2%)
Query: 1179 EAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGE--DARFRMFSKQGVL 1236
+AP F + V G A C V GSP+P +SW K+G LGE R R+
Sbjct: 108 QAPHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEAS 167
Query: 1237 TLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
L IR P DGG Y RA N G A L V
Sbjct: 168 ALRIRAARPRDGGTYEVRAENPLGAASAAAALVV 201
Score = 50.1 bits (118), Expect = 1e-05
Identities = 85/397 (21%), Positives = 141/397 (35%), Gaps = 81/397 (20%)
Query: 437 VVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGA-QVKWLKDGVELTR 495
VV E + L PV +T L++Q V G V F+C V+ + V+W KDG L
Sbjct: 5110 VVPPEPLPSLLTSDAAPVFLTE-LQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLL-- 5166
Query: 496 EETFKYRFKKDGQR-HHLIINEAMLEDAGHYALCTSGGQALA------------------ 536
EE Y +D Q H LII + D G Y ++
Sbjct: 5167 EEDDHYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTA 5226
Query: 537 ------------------------ELIVQEKKL-EVYQSIADLMVGAKDQ-AVFKCEVSD 570
E E +L +V + + DL V + A F+ +V
Sbjct: 5227 ADATESSSYFSAQGYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKG 5286
Query: 571 ENV-RGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADY-SFVPEGFACNLSAK 628
R W K+G+ L + I+++ +H L I VT D Y +++ S+
Sbjct: 5287 YPAPRLYWFKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSA 5346
Query: 629 LHFMEVKIDFVPRQEPPK-IHLD-CPGRIPDTIV---VVAGNKLRLDVPISGDPAPTVIW 683
+ V+ P ++P +H P R+ + V G+ + V + G P PTV W
Sbjct: 5347 R--LLVRGPDEPEEKPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHW 5404
Query: 684 QKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEK 743
+ + + PD P T V ++ + + +
Sbjct: 5405 LR--EEAERGVLWIGPDTPGYT---------------------VASSAQQHSLVLLDVGR 5441
Query: 744 EDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPKI 780
+ +G YT N G+ + ++ V +P K+
Sbjct: 5442 QHQGTYTCIASNAAGQALCSASLHVSGLPKVEEQEKV 5478
Score = 49.7 bits (117), Expect = 2e-05
Identities = 36/131 (27%), Positives = 53/131 (40%), Gaps = 8/131 (6%)
Query: 14 KKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGP 73
K PR V G A+F E V W R ++ A + ++ EGTRHTLT+ +
Sbjct: 425 KLPRKTAVRVGDTAMFCVELAVPVGPVHWLRNQEEVVAGGRVAISAEGTRHTLTISQCCL 484
Query: 74 ADQGSYAVIAGSSKVKFDLKVIEAEKAEPMLAPAPAPAEATGAPGEAPAPAAELGESAPS 133
D G A +AG + V K P L P P +A ++ + +P
Sbjct: 485 EDVGQVAFMAGDCQTSTQFCVSAPRK--PPLQPPVDPVV------KARMESSVILSWSPP 536
Query: 134 PKGSSSAALNG 144
P G ++G
Sbjct: 537 PHGERPVTIDG 547
Score = 49.7 bits (117), Expect = 2e-05
Identities = 34/99 (34%), Positives = 44/99 (44%), Gaps = 1/99 (1%)
Query: 1176 DFSEAPSFTQPLVNRSVIAGYT-AMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQG 1234
D + P + L + V G A V+G P P++ WFK+G L A RM K+
Sbjct: 5255 DEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIRMTDKKI 5314
Query: 1235 VLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVRVP 1273
+ TLEI D G Y +N G A RL VR P
Sbjct: 5315 LHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGP 5353
Score = 49.3 bits (116), Expect = 2e-05
Identities = 31/101 (30%), Positives = 45/101 (44%), Gaps = 1/101 (0%)
Query: 1174 ALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMF-SK 1232
AL P F + L + + G T L C V G+PKP ISW+K+G + D +
Sbjct: 6007 ALPVWRPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDP 6066
Query: 1233 QGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVRVP 1273
G L + D G Y+C A + G ++ V+VP
Sbjct: 6067 DGSCALILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVP 6107
Score = 48.9 bits (115), Expect = 3e-05
Identities = 48/166 (28%), Positives = 60/166 (36%), Gaps = 31/166 (18%)
Query: 856 RPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSE 915
R + AS +G P P V S TV+L W P G GGL GY VE +
Sbjct: 4509 RDAVASARLTVLGLPDPPEDAEVVARSSHTVTLSWAAPMSDGGGGLCGYRVEVKEGATGQ 4568
Query: 916 WVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQL 975
W L +V L G FRV A G G PV
Sbjct: 4569 W-RLCHELVPGPECVVDGLAPGETYRFRVAAVGPVGAGEPV------------------- 4608
Query: 976 PRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSI 1021
HL QT+ ++ EP + P P + Q AGE+VS+
Sbjct: 4609 --HLPQTV--RLAEPPKPVPPQPSAPESR-------QVAAGEDVSL 4643
Score = 47.8 bits (112), Expect = 7e-05
Identities = 74/311 (23%), Positives = 111/311 (35%), Gaps = 26/311 (8%)
Query: 987 VGEPVNLLIPFQGKPRPQVTWTKEGQPLA-GEEVSIRNSPTDTILFIRAARRVHSGTYQV 1045
VG+ L G P PQV+W K+ QP+A G + L I SG Y
Sbjct: 23 VGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDLALGDSGQYVC 82
Query: 1046 TVRIENMEDKATLVLQVVDKPS----------PPQDLRVTDAWGLNVALEWKPPQDVGNT 1095
R E A + LQV + + P +RV + G +
Sbjct: 83 RARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTSIRVRE--GSEATFRCRVGGSPRPA 140
Query: 1096 ELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGF-------- 1147
W ++ + V E + + +G + V ++N +G
Sbjct: 141 VSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAASAAAALV 200
Query: 1148 --SDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRS--VIAGYTAMLCCA 1203
SD A T P + + +A+ AP+ R+ V G A L C
Sbjct: 201 VDSDAADTASRPGTSTAALLAHLQRRREAMRAEGAPASPPSTGTRTCTVTEGKHARLSCY 260
Query: 1204 VRGSPKPKISWFKNGLDLGEDARFRMF-SKQGVLTLEIRKPCPFDGGIYVCRATNLQGEA 1262
V G PKP+ W K+G + E R ++ Q L+I D G+Y C A+NL G+
Sbjct: 261 VTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQT 320
Query: 1263 RCECRLEVRVP 1273
+ VR P
Sbjct: 321 YSSVLVVVREP 331
Score = 47.4 bits (111), Expect = 9e-05
Identities = 54/243 (22%), Positives = 89/243 (36%), Gaps = 50/243 (20%)
Query: 555 MVGAKDQAVFKCEVSDENVRGV-WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEAD 613
+V A C++ V W K+ + + +R +++ G +++LTI D+ D
Sbjct: 20 VVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDLALGDSGQ 79
Query: 614 Y-----SFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLR 668
Y + + E FA ++V + ++ P L P +I V G++
Sbjct: 80 YVCRARNAIGEAFAA------VGLQVDAEAACAEQAPHFLLR-----PTSIRVREGSEAT 128
Query: 669 LDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEG-RVRV 727
+ G P P V W K D + L E +G RVRV
Sbjct: 129 FRCRVGGSPRPAVSWSK----------------------------DGRRLGEPDGPRVRV 160
Query: 728 ETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDS 787
E + S + A D G Y V +NP+G + V D+ AA S G +
Sbjct: 161 EELGEASALRIRAARPRDGGTYEVRAENPLGAASAAAAL----VVDSDAADTASRPGTST 216
Query: 788 CTV 790
+
Sbjct: 217 AAL 219
Score = 46.6 bits (109), Expect = 2e-04
Identities = 23/83 (27%), Positives = 40/83 (48%), Gaps = 1/83 (1%)
Query: 12 FSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREV 71
F + ++ E G+ AV + E +A V W++G + ++Y L +GTR L + +
Sbjct: 3804 FIEDVKNQEAREGATAVLQCELSKAA-PVEWRKGSETLRGGDRYSLRQDGTRCELQIHGL 3862
Query: 72 GPADQGSYAVIAGSSKVKFDLKV 94
AD G Y+ + G + L V
Sbjct: 3863 SVADTGEYSCVCGQERTSATLTV 3885
Score = 44.7 bits (104), Expect = 6e-04
Identities = 23/83 (27%), Positives = 40/83 (48%), Gaps = 1/83 (1%)
Query: 12 FSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREV 71
F + ++ E G+ AV + E A V W++G + ++Y L +GT+ L +R +
Sbjct: 3540 FIEDVKNQEAREGATAVLQCELNSAA-PVEWRKGSETLRDGDRYSLRQDGTKCELQIRGL 3598
Query: 72 GPADQGSYAVIAGSSKVKFDLKV 94
AD G Y+ + G + L V
Sbjct: 3599 AMADTGEYSCVCGQERTSAMLTV 3621
Score = 43.5 bits (101), Expect = 0.001
Identities = 27/87 (31%), Positives = 39/87 (44%), Gaps = 1/87 (1%)
Query: 8 PVSAFSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLT 67
PVS FS+ + V E E R V VRW + G ++ A +A +G +LT
Sbjct: 2165 PVS-FSRPLQDVVTTEKEKVTLECELSRPNVDVRWLKDGVELRAGKTMAIAAQGACRSLT 2223
Query: 68 VREVGPADQGSYAVIAGSSKVKFDLKV 94
+ ADQG Y A ++ +KV
Sbjct: 2224 IYRCEFADQGVYVCDAHDAQSSASVKV 2250
Score = 42.4 bits (98), Expect = 0.003
Identities = 76/356 (21%), Positives = 128/356 (35%), Gaps = 45/356 (12%)
Query: 915 EWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRL- 973
+W+ L ++ ++ T RL+ R M GP TV + RL
Sbjct: 2411 KWLLGKTVLQAGGNVGLEQEGTVHRLMLRRTCSTMTGP-------VHFTVGKSRSSARLV 2463
Query: 974 --QLPRHLRQTIQKKVGEPV-NLLIPFQGKPRPQ-VTWTKEGQPLAGEEVSIRNSPTDTI 1029
+P L + ++ K G + ++++ +P P+ V W K+ PL+ E + S +
Sbjct: 2464 VSDIPVVLTRPLEPKTGRELQSVVLSCDFRPAPKAVQWYKDDTPLSPSE-KFKMSLEGQM 2522
Query: 1030 LFIRAARRV--HSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWK 1087
+R R + +G Y+ + + T+ + V P QD T+ + + E
Sbjct: 2523 AELRILRLMPADAGVYRCQAGSAHSSTEVTVEAREVTVTGPLQDAEATEEGWASFSCELS 2582
Query: 1088 PPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGF 1147
+ L G + + F + H R H +V + I S V
Sbjct: 2583 HEDEEVEWSLNGMPLYN------DSFHEISHKGRRHTLVLKSIQRADAGIVRASSLKVST 2636
Query: 1148 SDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGS 1207
S R +PV KALD A R +A L C V
Sbjct: 2637 SARLEVRVKPVVF-----------LKALDDLSAEE-------RGTLA-----LQCEV-SD 2672
Query: 1208 PKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEAR 1263
P+ + W K+G+ LG ++ G L + P D G+Y C + + AR
Sbjct: 2673 PEAHVVWRKDGVQLGPSDKYDFLHTAGTRGLVVHDVSPEDAGLYTCHVGSEETRAR 2728
Score = 42.0 bits (97), Expect = 0.004
Identities = 26/81 (32%), Positives = 40/81 (49%), Gaps = 5/81 (6%)
Query: 1194 AGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVC 1253
AG TAML C V P+ +++W+K+G L ++ RM K L +++ D G Y C
Sbjct: 1180 AGTTAMLSCEV-AQPQTEVTWYKDGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEYSC 1238
Query: 1254 RATNLQGEARCECRLEVRVPQ 1274
A G R +L + P+
Sbjct: 1239 EA----GGQRVSFQLHITEPK 1255
Score = 41.6 bits (96), Expect = 0.005
Identities = 24/83 (28%), Positives = 34/83 (40%)
Query: 12 FSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREV 71
F KK V S E E R ++RW R + ++ + EG RH L + V
Sbjct: 1990 FKKKLEPQTVEERSSVTLEVELTRPWPELRWTRNATALAPGKNVEIHAEGARHRLVLHNV 2049
Query: 72 GPADQGSYAVIAGSSKVKFDLKV 94
G AD+G + K + L V
Sbjct: 2050 GFADRGFFGCETPDDKTQAKLTV 2072
Score = 40.8 bits (94), Expect = 0.008
Identities = 26/90 (28%), Positives = 41/90 (45%), Gaps = 5/90 (5%)
Query: 18 SVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQG 77
+V G A F+ + V V W R G+ + S K+ ++ G H+LT+ ++ D G
Sbjct: 1907 TVVAEEGGEATFQCVVSPSDVAVVWFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAG 1966
Query: 78 SYAVIAGSSKVKFDLKVIEA-----EKAEP 102
V A + L+V EA +K EP
Sbjct: 1967 QITVEAEGASSSAALRVREAPVLFKKKLEP 1996
Score = 40.4 bits (93), Expect = 0.011
Identities = 22/83 (26%), Positives = 39/83 (46%), Gaps = 1/83 (1%)
Query: 12 FSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREV 71
F++ R+ E G+ A+ E + V W++G ++ ++Y L EGTR L + +
Sbjct: 3452 FTEGLRNEEAVEGATAMLWCELSKVA-PVEWRKGPENLRDGDRYILRQEGTRCELQICGL 3510
Query: 72 GPADQGSYAVIAGSSKVKFDLKV 94
AD G Y + G + L +
Sbjct: 3511 AMADAGEYLCVCGQERTSATLTI 3533
Score = 40.4 bits (93), Expect = 0.011
Identities = 21/73 (28%), Positives = 32/73 (43%)
Query: 7 KPVSAFSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTL 66
KPV P S +VAAG E E +V W +G I ++ + ++G + L
Sbjct: 4621 KPVPPQPSAPESRQVAAGEDVSLELEVVAEAGEVIWHKGMERIQPGGRFEVVSQGRQQML 4680
Query: 67 TVREVGPADQGSY 79
++ DQG Y
Sbjct: 4681 VIKGFTAEDQGEY 4693
Score = 40.0 bits (92), Expect = 0.014
Identities = 22/85 (25%), Positives = 38/85 (44%), Gaps = 1/85 (1%)
Query: 10 SAFSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVR 69
S F + R+ E G A E +A V W++G + +++ L +G+R L +R
Sbjct: 3714 SKFIEGLRNEEATEGDTATLWCELSKAA-PVEWRKGHETLRDGDRHSLRQDGSRCELQIR 3772
Query: 70 EVGPADQGSYAVIAGSSKVKFDLKV 94
+ D G Y+ + G + L V
Sbjct: 3773 GLAVVDAGEYSCVCGQERTSATLTV 3797
Score = 39.7 bits (91), Expect = 0.019
Identities = 26/73 (35%), Positives = 36/73 (49%), Gaps = 5/73 (6%)
Query: 982 TIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLA---GEEVSIRNSPTDTILFIRAARRV 1038
+I+ + G G PRP V+W+K+G+ L G V + + L IRAAR
Sbjct: 118 SIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPR 177
Query: 1039 HSGTYQVTVRIEN 1051
GTY+ VR EN
Sbjct: 178 DGGTYE--VRAEN 188
Score = 39.3 bits (90), Expect = 0.024
Identities = 26/79 (32%), Positives = 36/79 (45%), Gaps = 13/79 (16%)
Query: 435 QCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEV-SEEGAQVKWLKDGVEL 493
Q G K E+ +E P + + D VG + EC V S+ + +WLKDGVEL
Sbjct: 4880 QAAFKGYKVRKEMKQQEGP-MFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVEL 4938
Query: 494 TREETFKYRFKKDGQRHHL 512
T DG+ HH+
Sbjct: 4939 T-----------DGRHHHI 4946
Score = 38.5 bits (88), Expect = 0.041
Identities = 41/181 (22%), Positives = 65/181 (35%), Gaps = 21/181 (11%)
Query: 452 PPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKKDGQRHH 511
P + + PL+ + G V F +++ A +W DG L Y D RH
Sbjct: 611 PKLAVRTPLKAVQAVEGGEVTFSVDLTVASAG-EWFLDGQALKASSV--YEIHCDRTRHT 667
Query: 512 LIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQS------------IADLMVGAK 559
L I E G + G I ++EV + +++
Sbjct: 668 LTIREVPASLHGAQLKFVANG------IESSIRMEVRAAPGLTANKPPAAAAREVLARLH 721
Query: 560 DQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPE 619
++A E+SD+ WLK+G+ L P + +V L + DV D Y V
Sbjct: 722 EEAQLLAELSDQAAAVTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYECVSR 781
Query: 620 G 620
G
Sbjct: 782 G 782
Score = 38.5 bits (88), Expect = 0.041
Identities = 31/116 (26%), Positives = 47/116 (40%), Gaps = 2/116 (1%)
Query: 17 RSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQ 76
++V+ G F + A W G + AS+ Y + + TRHTLT+REV +
Sbjct: 620 KAVQAVEGGEVTFSVDLTVASAG-EWFLDGQALKASSVYEIHCDRTRHTLTIREVPASLH 678
Query: 77 GS-YAVIAGSSKVKFDLKVIEAEKAEPMLAPAPAPAEATGAPGEAPAPAAELGESA 131
G+ +A + ++V A PA A E E AEL + A
Sbjct: 679 GAQLKFVANGIESSIRMEVRAAPGLTANKPPAAAAREVLARLHEEAQLLAELSDQA 734
Score = 37.7 bits (86), Expect = 0.071
Identities = 31/104 (29%), Positives = 48/104 (46%), Gaps = 9/104 (8%)
Query: 1175 LDFSEAPSF--TQPLVNRSVIA--GYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMF 1230
LD SE + + L +R V A G A L C V + +++W+K+G L ++ RM
Sbjct: 1341 LDVSEPKAVFAKEQLAHRKVQAEAGAIATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRME 1399
Query: 1231 SKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVRVPQ 1274
+ L +++ C D G Y C A G R L+V P+
Sbjct: 1400 AVGCTRRLVVQQACQADTGEYSCEA----GGQRLSFSLDVAEPK 1439
Score = 37.0 bits (84), Expect = 0.12
Identities = 28/92 (30%), Positives = 38/92 (41%), Gaps = 6/92 (6%)
Query: 17 RSVEVAAGSPAVFEAETERAGVKV-RWQRGGSDISASNKYGLATEGTRHTLTVREVGPAD 75
+ V V +PA FE ET V+ +W G + + A GL EGT H L +R
Sbjct: 2386 QDVTVMEPAPAWFECETSIPSVRPPKWLLGKTVLQAGGNVGLEQEGTVHRLMLRRTCSTM 2445
Query: 76 QGSYAVIAGSSK-----VKFDLKVIEAEKAEP 102
G G S+ V D+ V+ EP
Sbjct: 2446 TGPVHFTVGKSRSSARLVVSDIPVVLTRPLEP 2477
Score = 37.0 bits (84), Expect = 0.12
Identities = 28/92 (30%), Positives = 40/92 (43%), Gaps = 5/92 (5%)
Query: 1183 FTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRK 1242
F + L ++ V G TA LCC + + + W K L L A+++M L +R
Sbjct: 3981 FLRELQHQEVDEGGTAHLCCELSRAGA-SVEWRKGSLQLFPCAKYQMVQDGAAAELLVRG 4039
Query: 1243 PCPFDGGIYVCRATNLQGEARCECRLEVRVPQ 1274
D G Y C + Q A L VRVP+
Sbjct: 4040 VEQEDAGDYTCDTGHTQSMA----SLSVRVPR 4067
Score = 36.2 bits (82), Expect = 0.21
Identities = 23/81 (28%), Positives = 39/81 (48%), Gaps = 5/81 (6%)
Query: 1194 AGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVC 1253
AG +A L C V + +++W+K+G L ++ RM + L +++ D G Y C
Sbjct: 1548 AGTSATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQEAGQADAGEYSC 1606
Query: 1254 RATNLQGEARCECRLEVRVPQ 1274
+A G+ R L V P+
Sbjct: 1607 KA----GDQRLSFHLHVAEPK 1623
Score = 36.2 bits (82), Expect = 0.21
Identities = 21/83 (25%), Positives = 36/83 (43%), Gaps = 1/83 (1%)
Query: 12 FSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREV 71
F++ R+ E G+ AV E + V W +G + +++ L +G R L +R +
Sbjct: 3628 FTEGLRNEEATEGATAVLRCELSKMA-PVEWWKGHETLRDGDRHSLRQDGARCELQIRGL 3686
Query: 72 GPADQGSYAVIAGSSKVKFDLKV 94
D G Y + G + L V
Sbjct: 3687 VAEDAGEYLCMCGKERTSAMLTV 3709
Score = 35.0 bits (79), Expect = 0.46
Identities = 18/57 (31%), Positives = 28/57 (49%)
Query: 40 VRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYAVIAGSSKVKFDLKVIE 96
V W + G +I S ++ A++G HTLTV D Y+ G+ F ++V E
Sbjct: 1750 VTWLKDGVEIRRSKRHETASQGDTHTLTVHGAQVLDSAIYSCRVGAEGQDFPVQVEE 1806
Score = 34.7 bits (78), Expect = 0.60
Identities = 22/81 (27%), Positives = 39/81 (48%), Gaps = 5/81 (6%)
Query: 1194 AGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVC 1253
AG +A L C V + +++W+K+G L ++ R+ + + L +++ D G Y C
Sbjct: 1272 AGASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEYTC 1330
Query: 1254 RATNLQGEARCECRLEVRVPQ 1274
A G R L+V P+
Sbjct: 1331 EA----GGQRLSFHLDVSEPK 1347
Score = 33.9 bits (76), Expect = 1.0
Identities = 43/154 (27%), Positives = 61/154 (39%), Gaps = 28/154 (18%)
Query: 3 EPGKKPVSAFSKK---PRSVE------VAAGSPAVFEAETERAGVK-VRWQRGGSDISA- 51
EP +KP S ++ PR +E V GS F + E V V W R ++
Sbjct: 5355 EPEEKPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVL 5414
Query: 52 -----SNKYGLATEGTRHTLTVREVGPADQGSYAVIA----------GSSKVKFDLKVIE 96
+ Y +A+ +H+L + +VG QG+Y IA S V KV E
Sbjct: 5415 WIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHVSGLPKVEE 5474
Query: 97 AEKAEPMLAPA--PAPAEATGAPGEAPAPAAELG 128
EK + L +A A G A A+LG
Sbjct: 5475 QEKVKEALISTFLQGTTQAISAQGLETASFADLG 5508
Score = 33.5 bits (75), Expect = 1.3
Identities = 19/61 (31%), Positives = 24/61 (39%)
Query: 17 RSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQ 76
++VE A E + A V W R G LA G HTLT+ + P D
Sbjct: 2084 QAVEAREQGTATMEVQLSHADVDGSWTRDGLRFQQGPTCHLAVRGPMHTLTLSGLRPEDS 2143
Query: 77 G 77
G
Sbjct: 2144 G 2144
Score = 33.1 bits (74), Expect = 1.7
Identities = 22/81 (27%), Positives = 38/81 (46%), Gaps = 5/81 (6%)
Query: 1194 AGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVC 1253
AG +A L C V + +++W+K+G L ++ M + L +++ D G Y C
Sbjct: 904 AGASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEYSC 962
Query: 1254 RATNLQGEARCECRLEVRVPQ 1274
A G R L+V+ P+
Sbjct: 963 EA----GGQRLSFHLDVKEPK 979
Score = 33.1 bits (74), Expect = 1.7
Identities = 23/81 (28%), Positives = 36/81 (44%), Gaps = 5/81 (6%)
Query: 1194 AGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVC 1253
AG +AML C V + +++W+K+G L ++ M K L + + D G Y C
Sbjct: 1088 AGASAMLSCEV-AQAQTEVTWYKDGKKLSSSSKVGMEVKGCTRRLVLPQAGKADAGEYSC 1146
Query: 1254 RATNLQGEARCECRLEVRVPQ 1274
A G R L + P+
Sbjct: 1147 EA----GGQRVSFHLHITEPK 1163
Score = 32.3 bits (72), Expect = 3.0
Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 5/77 (6%)
Query: 1194 AGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVC 1253
AG +A L C V + +++W+K+G L ++ R+ + L +++ D G Y C
Sbjct: 1640 AGASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRVEAVGCTRRLVVQQAGQADAGEYSC 1698
Query: 1254 RATNLQGEARCECRLEV 1270
A G R RL V
Sbjct: 1699 EA----GGQRLSFRLHV 1711
Score = 32.3 bits (72), Expect = 3.0
Identities = 25/89 (28%), Positives = 39/89 (43%), Gaps = 6/89 (6%)
Query: 1183 FTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRK 1242
FT+ L N + G TAML C + S + W K +L + R+ + + L+I
Sbjct: 3452 FTEGLRNEEAVEGATAMLWCEL--SKVAPVEWRKGPENLRDGDRYILRQEGTRCELQICG 3509
Query: 1243 PCPFDGGIYVCRATNLQGEARCECRLEVR 1271
D G Y+C + G+ R L +R
Sbjct: 3510 LAMADAGEYLC----VCGQERTSATLTIR 3534
Score = 32.3 bits (72), Expect = 3.0
Identities = 19/60 (31%), Positives = 27/60 (45%), Gaps = 3/60 (5%)
Query: 988 GEPVNLLIPFQGKPRPQVTWTKEGQPL-AGEEVSIRNSPTD--TILFIRAARRVHSGTYQ 1044
GE +G P PQ+ W K+G L G + + P +L IRAA + G Y+
Sbjct: 6122 GEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYE 6181
Score = 32.0 bits (71), Expect = 3.9
Identities = 21/80 (26%), Positives = 36/80 (45%), Gaps = 8/80 (10%)
Query: 27 AVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYAVIAGSS 86
A F E +V W G + + + ++ +G RHTL ++ + AD G ++ SS
Sbjct: 2575 ASFSCELSHEDEEVEWSLNGMPLYNDSFHEISHKGRRHTLVLKSIQRADAG---IVRASS 2631
Query: 87 KVKFDLKVIEAEKAEPMLAP 106
LKV + + E + P
Sbjct: 2632 -----LKVSTSARLEVRVKP 2646
Score = 32.0 bits (71), Expect = 3.9
Identities = 23/91 (25%), Positives = 35/91 (38%), Gaps = 3/91 (3%)
Query: 1173 KALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSK 1232
K + E P F+ + G L C V + W K+G++L D R +
Sbjct: 4890 KEMKQQEGPMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVEL-TDGRHHHIDQ 4948
Query: 1233 --QGVLTLEIRKPCPFDGGIYVCRATNLQGE 1261
G +L I D G Y C+ +N G+
Sbjct: 4949 LGDGTCSLLITGLDRADAGCYTCQVSNKFGQ 4979
Score = 31.6 bits (70), Expect = 5.1
Identities = 23/82 (28%), Positives = 38/82 (46%), Gaps = 3/82 (3%)
Query: 1182 SFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIR 1241
SF++PL + L C + P + W K+G++L + ++ +L I
Sbjct: 2167 SFSRPLQDVVTTEKEKVTLECEL-SRPNVDVRWLKDGVELRAGKTMAIAAQGACRSLTIY 2225
Query: 1242 KPCPF-DGGIYVCRATNLQGEA 1262
+ C F D G+YVC A + Q A
Sbjct: 2226 R-CEFADQGVYVCDAHDAQSSA 2246
Score = 31.6 bits (70), Expect = 5.1
Identities = 54/238 (22%), Positives = 80/238 (33%), Gaps = 36/238 (15%)
Query: 12 FSKKPRSVEVAAGSPAVFEAE-TERAGVKVRWQRGGSDISASNKYGLATEGTR-HTLTVR 69
F + ++ EV G P F+ T + VRW + G + + Y + + H L +
Sbjct: 5128 FLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQLIIT 5187
Query: 70 EVGPADQGSYAVIA----GSSKVKFDLKVIEAEKAEPMLAPAPAPAEATGAPGEAPAPAA 125
V PAD G Y +A G S K +L+V + T + A A
Sbjct: 5188 AVVPADMGVYRCLAENSMGVSSTKAELRV-----------------DLTSTDYDTAADAT 5230
Query: 126 ELGESAPSPKGSSSAALNGPTPGAPDDPIGLFVMRPQDGEVTVGGSIT-FSARVAGASLL 184
E + SS G + + V +D +V G + F +V G
Sbjct: 5231 ESSSYFSAQGYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKG---Y 5287
Query: 185 KPPVVKWFKGKWVDLSSKVGQHLQLHDSYDRASKVYLFELHITDAQPAFTGSYRCEVS 242
P + WFK GQ L K L L I +G Y +S
Sbjct: 5288 PAPRLYWFKD---------GQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYIS 5336
Score = 31.2 bits (69), Expect = 6.6
Identities = 20/78 (25%), Positives = 34/78 (43%), Gaps = 5/78 (6%)
Query: 1178 SEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPK-ISWFKNGLDLGEDARFRMFSKQGVL 1236
SE P +PLV + + ++ A +P ++W K+G+++ R S+
Sbjct: 1719 SERPCRREPLV----VKEHEDIILTATLATPSAATVTWLKDGVEIRRSKRHETASQGDTH 1774
Query: 1237 TLEIRKPCPFDGGIYVCR 1254
TL + D IY CR
Sbjct: 1775 TLTVHGAQVLDSAIYSCR 1792
Score = 30.8 bits (68), Expect = 8.6
Identities = 24/95 (25%), Positives = 37/95 (38%), Gaps = 5/95 (5%)
Query: 1181 PSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKI-SWFKNGLDLGEDARFRMFSKQGVLTLE 1239
P F L + G A LCC + + + W K G++L ++ M S+ L
Sbjct: 4068 PKFKTRLQSLEQETGDIARLCCQLSDAESGAVVQWLKEGVELHAGPKYEMRSQGATRELL 4127
Query: 1240 IRKPCPFDGGIYVCRATNLQGEARCECRLEVRVPQ 1274
I + D G Y C + G + L V P+
Sbjct: 4128 IHQLEAKDTGEYAC----VTGGQKTAASLRVTEPE 4158
Score = 30.8 bits (68), Expect = 8.6
Identities = 16/33 (48%), Positives = 21/33 (63%), Gaps = 1/33 (3%)
Query: 144 GPTPGAPDD-PIGLFVMRPQDGEVTVGGSITFS 175
GP PGAPDD P + V++ + GE TVG + S
Sbjct: 6484 GPGPGAPDDPPCEVSVIQREIGEPTVGQPVLLS 6516
>gi|148833506 obscurin, cytoskeletal calmodulin and titin-interacting
RhoGEF isoform b [Homo sapiens]
Length = 7968
Score = 151 bits (381), Expect = 4e-36
Identities = 179/739 (24%), Positives = 285/739 (38%), Gaps = 113/739 (15%)
Query: 7 KPVSAFSKKP---RSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTR 63
+P F+K+ V+ AG+ A+ E +A +V W + G +S+S+K G+ +G
Sbjct: 1069 EPKMMFAKEQSVHNEVQAEAGASAMLSCEVAQAQTEVTWYKDGKKLSSSSKVGMEVKGCT 1128
Query: 64 HTLTVREVGPADQGSYAVIAGSSKVKFDLKVIEAE----KAEPMLAPAPAPAEATGAPG- 118
L + + G AD G Y+ AG +V F L + E + K + + A A T
Sbjct: 1129 RRLVLPQAGKADAGEYSCEAGGQRVSFHLHITEPKGVFAKEQSVHNEVQAEAGTTAMLSC 1188
Query: 119 EAPAPAAELGESAPSPKGSSSAALNGPTPGAPDDPIGLFVMRPQDGEVT----------- 167
E P E+ K SSS+ + G + V + GE +
Sbjct: 1189 EVAQPQTEVTWYKDGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEYSCEAGGQRVSFQ 1248
Query: 168 -----------------------VGGSITFSARVAGASLLKPPVVKWFK-GKWVDLSSKV 203
G S T S VA A V W+K GK + SSKV
Sbjct: 1249 LHITEPKAVFAKEQLVHNEVRTEAGASATLSCEVAQAQT----EVTWYKDGKKLSSSSKV 1304
Query: 204 GQHLQLHDSYDRASKVYLFELHITDAQPAFTGSYRCEVSTKDKFDCSNFNLTVHEAMGTG 263
+ + +L + A A G Y CE + +F+L V E
Sbjct: 1305 RIE----------AAGCMRQLVVQQAGQADAGEYTCEAGGQRL----SFHLDVSEPKAVF 1350
Query: 264 DLDLLSAFRRTSLAGGGRRISDSHEDTGILDFSSLLKKRDSFRTPRDSKLEAPA----EE 319
+ L+ + + AG +S + + +D + SK+ A
Sbjct: 1351 AKEQLAHRKVQAEAGAIATLSCEVAQAQ----TEVTWYKDGKKLSSSSKVRMEAVGCTRR 1406
Query: 320 DVWEILRQAPPSEY------ERIAFQYGVTDLRGMLKRLKGMRRDEKKSTAFQKKLEPAY 373
V + QA EY +R++F V + + + + + + R+
Sbjct: 1407 LVVQQACQADTGEYSCEAGGQRLSFSLDVAEPKVVFAKEQPVHRE--------------V 1452
Query: 374 QVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAA 433
Q G L+ E+A EV W K+G+++ S SK E++G R L + Q A
Sbjct: 1453 QAQAGASTTLSCEVAQAQTEVMWYKDGKKLSFS-SKVRMEAVGCTRRLVVQQAGQAVAGE 1511
Query: 434 YQCVVGGEKCSTELFVKEPPVLITR--PLEDQL-VMVGQRVEFECEVSEEGAQVKWLKDG 490
Y C G ++ S L V EP + + P ++ G CEV++ +V W KDG
Sbjct: 1512 YSCEAGSQRLSFHLHVAEPKAVFAKEQPASREVQAEAGTSATLSCEVAQAQTEVTWYKDG 1571
Query: 491 VELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALA-ELIVQEKKL---E 546
+L+ K R + G L++ EA DAG Y+ C +G Q L+ L V E K+ +
Sbjct: 1572 KKLSSSS--KVRMEAVGCTRRLVVQEAGQADAGEYS-CKAGDQRLSFHLHVAEPKVVFAK 1628
Query: 547 VYQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDV 606
+ ++ A A CEV+ W K+GK+L S+++V +G +L +
Sbjct: 1629 EQPAHREVQAEAGASATLSCEVAQAQTEVTWYKDGKKLSSSSKVRVEAVGCTRRLVVQQA 1688
Query: 607 TPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNK 666
AD +YS E LS +LH E+ EP C + +VV
Sbjct: 1689 GQADAGEYSC--EAGGQRLSFRLHVAEL--------EPQISERPCR---REPLVVKEHED 1735
Query: 667 LRLDVPISGDPAPTVIWQK 685
+ L ++ A TV W K
Sbjct: 1736 IILTATLATPSAATVTWLK 1754
Score = 149 bits (376), Expect = 2e-35
Identities = 173/683 (25%), Positives = 266/683 (38%), Gaps = 102/683 (14%)
Query: 19 VEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATE-GTRHTLTVREVGPADQG 77
V+ AG PA FE ET A V V W + G ++ S + L + GTRH L V D+G
Sbjct: 807 VDAVAGGPAQFECETSEAHVHVHWYKDGMELGHSGERFLQEDVGTRHRLVAATVTRQDEG 866
Query: 78 SYAVIAGSSKVKFDLKVIEAEK--AEPMLAPAPAPAEATGAPGEAPAPAAEL-------- 127
+Y+ G V F L+V E + A+ LA AEA GA A+
Sbjct: 867 TYSCRVGEDSVDFRLRVSEPKVVFAKEQLARRKLQAEA-GASATLSCEVAQAQTEVTWYK 925
Query: 128 -GESAPSPK------------------GSSSAALNGPTPGAPDDPIGLFVMRPQ------ 162
G+ S G + A G L V P+
Sbjct: 926 DGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEYSCEAGGQRLSFHLDVKEPKVVFAKD 985
Query: 163 -----DGEVTVGGSITFSARVAGASLLKPPVVKWFK-GKWVDLSSKVGQHLQLHDSYDRA 216
+ + G S T S VA A V W+K GK LSS + H++ R
Sbjct: 986 QVAHSEVQAEAGASATLSCEVAQAQ----TEVMWYKDGK--KLSSSLKVHVEAKGCRRR- 1038
Query: 217 SKVYLFELHITDAQPAFTGSYRCEVSTKDKFDCSNFNLTVHEAMGTGDLDLLSAFRRTSL 276
L + A G Y CE + + ++T + M + + + + +
Sbjct: 1039 -------LVVQQAGKTDAGDYSCE--ARGQRVSFRLHITEPKMMFAKEQSVHNEVQAEAG 1089
Query: 277 AGGGRRISDSHEDTGILDFSSLLKKRDSFRTPRDSK-------LEAPAEEDVWEILRQAP 329
A + T + + K S + + K L + D E +A
Sbjct: 1090 ASAMLSCEVAQAQTEVTWYKDGKKLSSSSKVGMEVKGCTRRLVLPQAGKADAGEYSCEAG 1149
Query: 330 PSEYERIAFQYGVTDLRGMLKRLKGMRRDEKKSTAFQKKLEPAYQVSKGHKIRLTVELAD 389
+R++F +T+ +G+ A ++ + Q G L+ E+A
Sbjct: 1150 G---QRVSFHLHITEPKGVF--------------AKEQSVHNEVQAEAGTTAMLSCEVAQ 1192
Query: 390 HDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCSTELFV 449
EV W K+G+++ S SK E G R L + Q AD Y C GG++ S +L +
Sbjct: 1193 PQTEVTWYKDGKKLS-SSSKVRMEVKGCTRRLVVQQVGKADAGEYSCEAGGQRVSFQLHI 1251
Query: 450 KEPPVLITRPLEDQLV------MVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRF 503
EP + + +QLV G CEV++ +V W KDG +L+ + K R
Sbjct: 1252 TEPKAVFAK---EQLVHNEVRTEAGASATLSCEVAQAQTEVTWYKDGKKLS--SSSKVRI 1306
Query: 504 KKDGQRHHLIINEAMLEDAGHYALCTSGGQALA-ELIVQE-KKLEVYQSIADLMVGAKDQ 561
+ G L++ +A DAG Y C +GGQ L+ L V E K + + +A V A+
Sbjct: 1307 EAAGCMRQLVVQQAGQADAGEYT-CEAGGQRLSFHLDVSEPKAVFAKEQLAHRKVQAEAG 1365
Query: 562 AV--FKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPE 619
A+ CEV+ W K+GK+L S++++ +G +L + AD +YS E
Sbjct: 1366 AIATLSCEVAQAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQQACQADTGEYSC--E 1423
Query: 620 GFACNLSAKLHFMEVKIDFVPRQ 642
LS L E K+ F Q
Sbjct: 1424 AGGQRLSFSLDVAEPKVVFAKEQ 1446
Score = 142 bits (357), Expect = 3e-33
Identities = 169/691 (24%), Positives = 275/691 (39%), Gaps = 92/691 (13%)
Query: 7 KPVSAFSKKP---RSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTR 63
+P F+K+ R ++ AG+ A E +A +V W + G +S+S+K + G
Sbjct: 885 EPKVVFAKEQLARRKLQAEAGASATLSCEVAQAQTEVTWYKDGKKLSSSSKVCMEATGCT 944
Query: 64 HTLTVREVGPADQGSYAVIAGSSKVKFDLKVIEAEK--AEPMLAPAPAPAEATGAPG--- 118
L V++ G AD G Y+ AG ++ F L V E + A+ +A + AEA GA
Sbjct: 945 RRLVVQQAGQADAGEYSCEAGGQRLSFHLDVKEPKVVFAKDQVAHSEVQAEA-GASATLS 1003
Query: 119 -EAPAPAAELGESAPSPKGSSSAALNGPTPGAPDDPIGLFVMRPQDGEVTV---GGSITF 174
E E+ K SSS ++ G + + G+ + G ++F
Sbjct: 1004 CEVAQAQTEVMWYKDGKKLSSSLKVHVEAKGCRRRLVVQQAGKTDAGDYSCEARGQRVSF 1063
Query: 175 SARV--------------------AGASLL-------KPPVVKWFK-GKWVDLSSKVGQH 206
+ AGAS + V W+K GK + SSKVG
Sbjct: 1064 RLHITEPKMMFAKEQSVHNEVQAEAGASAMLSCEVAQAQTEVTWYKDGKKLSSSSKVGME 1123
Query: 207 LQLHDSYDRASKVYLFELHITDAQPAFTGSYRCEVSTKDKFDCSNFNLTVHEAMGTGDLD 266
+ K L + A A G Y CE + +F+L + E G +
Sbjct: 1124 V----------KGCTRRLVLPQAGKADAGEYSCEAGGQR----VSFHLHITEPKGVFAKE 1169
Query: 267 LLSAFRRTSLAGGGRRIS--DSHEDTGILDFSSLLKKRDSFRTPRDSKLEAPAEEDVWEI 324
+ AG +S + T + + K S + + K V +
Sbjct: 1170 QSVHNEVQAEAGTTAMLSCEVAQPQTEVTWYKDGKKLSSSSKVRMEVK--GCTRRLVVQQ 1227
Query: 325 LRQAPPSEY------ERIAFQYGVTDLRGMLKRLKGMRRDEKKSTAFQKKLEPAYQVSKG 378
+ +A EY +R++FQ +T+ + + A ++ + + G
Sbjct: 1228 VGKADAGEYSCEAGGQRVSFQLHITEPKAVF--------------AKEQLVHNEVRTEAG 1273
Query: 379 HKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVV 438
L+ E+A EV W K+G+++ S SK E+ G R L + Q AD Y C
Sbjct: 1274 ASATLSCEVAQAQTEVTWYKDGKKLS-SSSKVRIEAAGCMRQLVVQQAGQADAGEYTCEA 1332
Query: 439 GGEKCSTELFVKEPPVLITR-PLEDQLVM--VGQRVEFECEVSEEGAQVKWLKDGVELTR 495
GG++ S L V EP + + L + V G CEV++ +V W KDG +L+
Sbjct: 1333 GGQRLSFHLDVSEPKAVFAKEQLAHRKVQAEAGAIATLSCEVAQAQTEVTWYKDGKKLS- 1391
Query: 496 EETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALA-ELIVQEKKLEVYQS---I 551
+ K R + G L++ +A D G Y+ C +GGQ L+ L V E K+ +
Sbjct: 1392 -SSSKVRMEAVGCTRRLVVQQACQADTGEYS-CEAGGQRLSFSLDVAEPKVVFAKEQPVH 1449
Query: 552 ADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADE 611
++ A CEV+ +W K+GK+L S++++ +G +L + A
Sbjct: 1450 REVQAQAGASTTLSCEVAQAQTEVMWYKDGKKLSFSSKVRMEAVGCTRRLVVQQAGQAVA 1509
Query: 612 ADYSFVPEGFACNLSAKLHFMEVKIDFVPRQ 642
+YS E + LS LH E K F Q
Sbjct: 1510 GEYSC--EAGSQRLSFHLHVAEPKAVFAKEQ 1538
Score = 140 bits (353), Expect = 8e-33
Identities = 167/697 (23%), Positives = 273/697 (39%), Gaps = 102/697 (14%)
Query: 6 KKPVSAFSKKP---RSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGT 62
K+P F+K V+ AG+ A E +A +V W + G +S+S K + +G
Sbjct: 976 KEPKVVFAKDQVAHSEVQAEAGASATLSCEVAQAQTEVMWYKDGKKLSSSLKVHVEAKGC 1035
Query: 63 RHTLTVREVGPADQGSYAVIAGSSKVKFDLKVIEAEK-----------------AEPMLA 105
R L V++ G D G Y+ A +V F L + E + A ML+
Sbjct: 1036 RRRLVVQQAGKTDAGDYSCEARGQRVSFRLHITEPKMMFAKEQSVHNEVQAEAGASAMLS 1095
Query: 106 --PAPAPAEATG-APGEAPAPAAELG-------------ESAPSPKGSSSAALNGPTPGA 149
A A E T G+ + ++++G ++ + G S G
Sbjct: 1096 CEVAQAQTEVTWYKDGKKLSSSSKVGMEVKGCTRRLVLPQAGKADAGEYSCEAGGQRVSF 1155
Query: 150 P---DDPIGLFVMRPQ---DGEVTVGGSITFSARVAGASLLKPPVVKWFK-GKWVDLSSK 202
+P G+F + + G + S VA V W+K GK + SSK
Sbjct: 1156 HLHITEPKGVFAKEQSVHNEVQAEAGTTAMLSCEVAQPQT----EVTWYKDGKKLSSSSK 1211
Query: 203 VGQHLQLHDSYDRASKVYLFELHITDAQPAFTGSYRCEVSTKDKFDCSNFNLTVHEAMGT 262
V + K L + A G Y CE + +F L + E
Sbjct: 1212 VRMEV----------KGCTRRLVVQQVGKADAGEYSCEAGGQRV----SFQLHITEPKAV 1257
Query: 263 GDLDLLSAFRRTSLAGGGRRISDSHEDTGILDFSSLLKKRDSFRTPRDSKLEAPAEEDVW 322
+ L + AG +S + + +D + SK+ A +
Sbjct: 1258 FAKEQLVHNEVRTEAGASATLSCEVAQAQ----TEVTWYKDGKKLSSSSKVRIEAAGCMR 1313
Query: 323 EIL----RQAPPSEY------ERIAFQYGVTDLRGMLKRLKGMRRDEKKSTAFQKKLEPA 372
+++ QA EY +R++F V++ + + K+ A +K
Sbjct: 1314 QLVVQQAGQADAGEYTCEAGGQRLSFHLDVSEPKAVFA---------KEQLAHRK----- 1359
Query: 373 YQVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDA 432
Q G L+ E+A EV W K+G+++ S SK E++G R L + Q AD
Sbjct: 1360 VQAEAGAIATLSCEVAQAQTEVTWYKDGKKLS-SSSKVRMEAVGCTRRLVVQQACQADTG 1418
Query: 433 AYQCVVGGEKCSTELFVKEPPVLITR--PLEDQL-VMVGQRVEFECEVSEEGAQVKWLKD 489
Y C GG++ S L V EP V+ + P+ ++ G CEV++ +V W KD
Sbjct: 1419 EYSCEAGGQRLSFSLDVAEPKVVFAKEQPVHREVQAQAGASTTLSCEVAQAQTEVMWYKD 1478
Query: 490 GVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALA-ELIVQEKK---L 545
G +L+ K R + G L++ +A AG Y+ C +G Q L+ L V E K
Sbjct: 1479 GKKLSFSS--KVRMEAVGCTRRLVVQQAGQAVAGEYS-CEAGSQRLSFHLHVAEPKAVFA 1535
Query: 546 EVYQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDD 605
+ + ++ A A CEV+ W K+GK+L S++++ +G +L + +
Sbjct: 1536 KEQPASREVQAEAGTSATLSCEVAQAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQE 1595
Query: 606 VTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQ 642
AD +YS + LS LH E K+ F Q
Sbjct: 1596 AGQADAGEYSC--KAGDQRLSFHLHVAEPKVVFAKEQ 1630
Score = 120 bits (301), Expect = 8e-27
Identities = 158/702 (22%), Positives = 260/702 (37%), Gaps = 95/702 (13%)
Query: 28 VFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYAVIAGSSK 87
V E + RA +VRW +G ++ KY L ++G L + +V D+ +Y AG K
Sbjct: 2308 VLECQVSRASAQVRWFKGSQELQPGPKYELVSDGLYRKLIISDVHAEDEDTYTCDAGDVK 2367
Query: 88 VKFD-------LKVIEAEKAEPMLAPAPAPAEA-TGAPGEAPAPAAELGESAPSPKGS-- 137
+ ++ + ++ PAPA E T P P P LG++ G+
Sbjct: 2368 TSAQFFVEEQSITIVRGLQDVTVMEPAPAWFECETSIPSVRP-PKWLLGKTVLQAGGNVG 2426
Query: 138 --------------SSAALNGP---TPGAPDDPIGLFV----------MRPQDGEVTVGG 170
+ + + GP T G L V + P+ G
Sbjct: 2427 LEQEGTVHRLMLRRTCSTMTGPVHFTVGKSRSSARLVVSDIPVVLTRPLEPKTGRELQSV 2486
Query: 171 SITFSARVAGASLLKPPVVKWFKGKWVDLSSKVGQHLQLHDSYDRASKVYLFELHITDAQ 230
++ R A P V+W+K L + + + + + EL I
Sbjct: 2487 VLSCDFRPA------PKAVQWYKDD---------TPLSPSEKFKMSLEGQMAELRILRLM 2531
Query: 231 PAFTGSYRCEVSTKDKFDCSNFNLTVHEAMGTGDLDLLSAFRRTSLAGGGRRISDSHEDT 290
PA G YRC+ + + + E TG L A T SHED
Sbjct: 2532 PADAGVYRCQAGSAHS--STEVTVEAREVTVTGPLQDAEA---TEEGWASFSCELSHEDE 2586
Query: 291 GI-LDFSSLLKKRDSFRTPRDSKLEAPAEEDVWEILRQAPPSEYERIAFQYGVTDLRGML 349
+ + + DSF + + V + +++A G+ +
Sbjct: 2587 EVEWSLNGMPLYNDSFH---EISHKGRRHTLVLKSIQRADA----------GIVRASSLK 2633
Query: 350 KRLKGMRRDEKKSTAFQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSK 409
K F K L+ +G + L E++D +A V W K+G ++ S K
Sbjct: 2634 VSTSARLEVRVKPVVFLKALDDLSAEERG-TLALQCEVSDPEAHVVWRKDGVQLGPS-DK 2691
Query: 410 YIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQ 469
Y F R L + S D Y C VG E+ + V + V IT+ L+ V+ G+
Sbjct: 2692 YDFLHTAGTRGLVVHDVSPEDAGLYTCHVGSEETRARVRVHDLHVGITKRLKTMEVLEGE 2751
Query: 470 RVEFECEVSEEGAQ--VKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYAL 527
FEC +S E A W G T + +++ + G+++ L++ EA DAG
Sbjct: 2752 SCSFECVLSHESASDPAMWTVGG--KTVGSSSRFQATRQGRKYILVVREAAPSDAGEVVF 2809
Query: 528 CTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPD 587
G + A LIV+E+ + + + D V + +CE+S WLK+ K +
Sbjct: 2810 SVRGLTSKASLIVRERPAAIIKPLEDQWVAPGEDVELRCELSRAGTPVHWLKDRKAIRKS 2869
Query: 588 SRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKI 647
+ V G + L I + D +Y+ E A +A LH E F +E +
Sbjct: 2870 QKYDVVCEGTMAMLVIRGASLKDAGEYTCEVE--ASKSTASLHVEEKANCFT--EELTNL 2925
Query: 648 HLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQ 689
++ G T V + PA TV W+K + +
Sbjct: 2926 QVEEKG----TAVFTCKTE---------HPAATVTWRKGLLE 2954
Score = 118 bits (295), Expect = 4e-26
Identities = 154/668 (23%), Positives = 251/668 (37%), Gaps = 97/668 (14%)
Query: 31 AETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYAVIAGSSKVKF 90
AE V W + G +S KY + R L VR+V D G Y ++ ++ +
Sbjct: 728 AELSDQAAAVTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYECVSRGGRIAY 787
Query: 91 DLKV------IEAEKAEPML-APAPAPAEATGAPGEAPA------PAAELG--------E 129
L V + + A + A A PA+ EA ELG E
Sbjct: 788 QLSVQGLARFLHKDMAGSCVDAVAGGPAQFECETSEAHVHVHWYKDGMELGHSGERFLQE 847
Query: 130 SAPSPKGSSSAALNGPTPGAPDDPIGL----FVMRPQDGEVT--------------VGGS 171
+ +A + G +G F +R + +V G S
Sbjct: 848 DVGTRHRLVAATVTRQDEGTYSCRVGEDSVDFRLRVSEPKVVFAKEQLARRKLQAEAGAS 907
Query: 172 ITFSARVAGASLLKPPVVKWFK-GKWVDLSSKVGQHLQLHDSYDRASKVYLFELHITDAQ 230
T S VA A V W+K GK + SSKV + L + A
Sbjct: 908 ATLSCEVAQAQ----TEVTWYKDGKKLSSSSKVCME----------ATGCTRRLVVQQAG 953
Query: 231 PAFTGSYRCEVSTKDKFDCSNFNLTVHEAMGTGDLDLLSAFRRTSLAGGGRRIS--DSHE 288
A G Y CE + +F+L V E D ++ + AG +S +
Sbjct: 954 QADAGEYSCEAGGQR----LSFHLDVKEPKVVFAKDQVAHSEVQAEAGASATLSCEVAQA 1009
Query: 289 DTGILDFSSLLKKRDSFRTPRDSK-------LEAPAEEDVWEILRQAPPSEYERIAFQYG 341
T ++ + K S + ++K ++ + D + +A +R++F+
Sbjct: 1010 QTEVMWYKDGKKLSSSLKVHVEAKGCRRRLVVQQAGKTDAGDYSCEA---RGQRVSFRLH 1066
Query: 342 VTDLRGMLKRLKGMRRDEKKSTAFQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQ 401
+T+ + M A ++ + Q G L+ E+A EV W K+G+
Sbjct: 1067 ITEPKMMF--------------AKEQSVHNEVQAEAGASAMLSCEVAQAQTEVTWYKDGK 1112
Query: 402 EIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCSTELFVKEPPVLITRPL- 460
++ S SK E G R L + Q AD Y C GG++ S L + EP + +
Sbjct: 1113 KLS-SSSKVGMEVKGCTRRLVLPQAGKADAGEYSCEAGGQRVSFHLHITEPKGVFAKEQS 1171
Query: 461 --EDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAM 518
+ G CEV++ +V W KDG +L+ + K R + G L++ +
Sbjct: 1172 VHNEVQAEAGTTAMLSCEVAQPQTEVTWYKDGKKLS--SSSKVRMEVKGCTRRLVVQQVG 1229
Query: 519 LEDAGHYALCTSGGQALA-ELIVQEKKLEVYQSIA---DLMVGAKDQAVFKCEVSDENVR 574
DAG Y+ C +GGQ ++ +L + E K + ++ A A CEV+
Sbjct: 1230 KADAGEYS-CEAGGQRVSFQLHITEPKAVFAKEQLVHNEVRTEAGASATLSCEVAQAQTE 1288
Query: 575 GVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEV 634
W K+GK+L S++++ G + +L + AD +Y+ E LS L E
Sbjct: 1289 VTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEYTC--EAGGQRLSFHLDVSEP 1346
Query: 635 KIDFVPRQ 642
K F Q
Sbjct: 1347 KAVFAKEQ 1354
Score = 115 bits (287), Expect = 3e-25
Identities = 88/318 (27%), Positives = 134/318 (42%), Gaps = 23/318 (7%)
Query: 374 QVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAA 433
Q G L+ E+A EV W K+G+++ S SK E+ G R L + Q AD
Sbjct: 901 QAEAGASATLSCEVAQAQTEVTWYKDGKKLS-SSSKVCMEATGCTRRLVVQQAGQADAGE 959
Query: 434 YQCVVGGEKCSTELFVKEPPVLITRPL---EDQLVMVGQRVEFECEVSEEGAQVKWLKDG 490
Y C GG++ S L VKEP V+ + + G CEV++ +V W KDG
Sbjct: 960 YSCEAGGQRLSFHLDVKEPKVVFAKDQVAHSEVQAEAGASATLSCEVAQAQTEVMWYKDG 1019
Query: 491 VELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKL--EVY 548
+L+ + K + G R L++ +A DAG Y+ G + L + E K+
Sbjct: 1020 KKLS--SSLKVHVEAKGCRRRLVVQQAGKTDAGDYSCEARGQRVSFRLHITEPKMMFAKE 1077
Query: 549 QSI-ADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVT 607
QS+ ++ A A+ CEV+ W K+GK+L S++ + G +L +
Sbjct: 1078 QSVHNEVQAEAGASAMLSCEVAQAQTEVTWYKDGKKLSSSSKVGMEVKGCTRRLVLPQAG 1137
Query: 608 PADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKL 667
AD +YS E +S LH E K F Q + + + AG
Sbjct: 1138 KADAGEYSC--EAGGQRVSFHLHITEPKGVFAKEQS-----------VHNEVQAEAGTTA 1184
Query: 668 RLDVPISGDPAPTVIWQK 685
L ++ P V W K
Sbjct: 1185 MLSCEVA-QPQTEVTWYK 1201
Score = 111 bits (278), Expect = 4e-24
Identities = 84/257 (32%), Positives = 123/257 (47%), Gaps = 8/257 (3%)
Query: 365 FQKKLEPAYQVSKGHKIRLTVELADHD--AEVKWLKNGQEIQMSGSKYIFESIGAKRTLT 422
F+ +L+ Q + G RL +L+D + A V+WLK G E+ +G KY S GA R L
Sbjct: 4070 FKTRLQSLEQET-GDIARLCCQLSDAESGAVVQWLKEGVELH-AGPKYEMRSQGATRELL 4127
Query: 423 ISQCSLADDAAYQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGA 482
I Q D Y CV GG+K + L V EP V I R L D V + VEF CEVS GA
Sbjct: 4128 IHQLEAKDTGEYACVTGGQKTAASLRVTEPEVTIVRGLVDAEVTADEDVEFSCEVSRAGA 4187
Query: 483 Q-VKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQ 541
V+W G+ L E + +DG+ H L + EDAG + + A+L V+
Sbjct: 4188 TGVQWCLQGLPLQSNEVTEVAV-RDGRIHTLRLKGVTPEDAGTVSFHLGNHASSAQLTVR 4246
Query: 542 EKKLEVYQSIADLMVGAKDQAVFKCEVSDENVRGV-WLKNGKELVPDSRIKVS-HIGRVH 599
++ + + + D+ + A F+C +S + + W G L + ++ G +H
Sbjct: 4247 APEVTILEPLQDVQLSEGQDASFQCRLSRASGQEARWALGGVPLQANEMNDITVEQGTLH 4306
Query: 600 KLTIDDVTPADEADYSF 616
LT+ VT D SF
Sbjct: 4307 LLTLHKVTLEDAGTVSF 4323
Score = 105 bits (262), Expect = 3e-22
Identities = 78/276 (28%), Positives = 118/276 (42%), Gaps = 40/276 (14%)
Query: 364 AFQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTI 423
+F + L+ K K+ L EL+ + +V+WLK+G E++ +G + GA R+LTI
Sbjct: 2167 SFSRPLQDVVTTEK-EKVTLECELSRPNVDVRWLKDGVELR-AGKTMAIAAQGACRSLTI 2224
Query: 424 SQCSLADDAAYQC-----------------------------------VVGGEKCSTELF 448
+C AD Y C V + +L
Sbjct: 2225 YRCEFADQGVYVCDAHDAQSSASVKVQGRTYTLIYRRVLAEDAGEIQFVAENAESRAQLR 2284
Query: 449 VKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKKDGQ 508
VKE PV + RPL D++ M R EC+VS AQV+W K EL + KY DG
Sbjct: 2285 VKELPVTLVRPLRDKIAMEKHRGVLECQVSRASAQVRWFKGSQEL--QPGPKYELVSDGL 2342
Query: 509 RHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFKCEV 568
LII++ ED Y + A+ V+E+ + + + + D+ V A F+CE
Sbjct: 2343 YRKLIISDVHAEDEDTYTCDAGDVKTSAQFFVEEQSITIVRGLQDVTVMEPAPAWFECET 2402
Query: 569 SDENVR-GVWLKNGKELVPDSRIKVSHIGRVHKLTI 603
S +VR WL L + + G VH+L +
Sbjct: 2403 SIPSVRPPKWLLGKTVLQAGGNVGLEQEGTVHRLML 2438
Score = 102 bits (253), Expect = 3e-21
Identities = 79/267 (29%), Positives = 113/267 (42%), Gaps = 7/267 (2%)
Query: 374 QVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAA 433
+V +G L EL+ A V+W K ++ +KY GA L + D
Sbjct: 3989 EVDEGGTAHLCCELSRAGASVEWRKGSLQL-FPCAKYQMVQDGAAAELLVRGVEQEDAGD 4047
Query: 434 YQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVS--EEGAQVKWLKDGV 491
Y C G + L V+ P L+ G C++S E GA V+WLK+GV
Sbjct: 4048 YTCDTGHTQSMASLSVRVPRPKFKTRLQSLEQETGDIARLCCQLSDAESGAVVQWLKEGV 4107
Query: 492 ELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSI 551
EL KY + G L+I++ +D G YA T G + A L V E ++ + + +
Sbjct: 4108 ELHAGP--KYEMRSQGATRELLIHQLEAKDTGEYACVTGGQKTAASLRVTEPEVTIVRGL 4165
Query: 552 ADLMVGAKDQAVFKCEVSDENVRGV-WLKNGKELVPDSRIKVS-HIGRVHKLTIDDVTPA 609
D V A + F CEVS GV W G L + +V+ GR+H L + VTP
Sbjct: 4166 VDAEVTADEDVEFSCEVSRAGATGVQWCLQGLPLQSNEVTEVAVRDGRIHTLRLKGVTPE 4225
Query: 610 DEADYSFVPEGFACNLSAKLHFMEVKI 636
D SF A + + EV I
Sbjct: 4226 DAGTVSFHLGNHASSAQLTVRAPEVTI 4252
Score = 100 bits (249), Expect = 9e-21
Identities = 105/396 (26%), Positives = 162/396 (40%), Gaps = 42/396 (10%)
Query: 375 VSKGHKIRLTVELADHDAE-VKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAA 433
V + I LT LA A V WLK+G EI+ S ++ S G TLT+ + D A
Sbjct: 1730 VKEHEDIILTATLATPSAATVTWLKDGVEIRRS-KRHETASQGDTHTLTVHGAQVLDSAI 1788
Query: 434 YQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVEL 493
Y C VG E + V+E R LE +G V CE+S A+V W +L
Sbjct: 1789 YSCRVGAEGQDFPVQVEEVAAKFCRLLEPVCGELGGTVTLACELSPACAEVVWRCGNTQL 1848
Query: 494 TREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIAD 553
+ F+ +G L + EDAG Y + A+L V ++ + S
Sbjct: 1849 RVGKRFQ--MVAEGPVRSLTVLGLRAEDAGEYVCESRDDHTSAQLTVSVPRVVKFMSGLS 1906
Query: 554 LMVGAKD-QAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEA 612
+V + +A F+C VS +V VW ++G L P + +S G H LTI D+ D
Sbjct: 1907 TVVAEEGGEATFQCVVSPSDVAVVWFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAG 1966
Query: 613 DYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVP 672
+ EG + SA L E + F + EP V + + L+V
Sbjct: 1967 QITVEAEG--ASSSAALRVREAPVLFKKKLEPQ--------------TVEERSSVTLEVE 2010
Query: 673 ISGDPAPTVIWQKAITQGNKAPARPAPDAPE---------DTGDSDEWVFDKKLLCE--- 720
++ P P + W + T AP + E + G +D F CE
Sbjct: 2011 LT-RPWPELRWTRNATA--LAPGKNVEIHAEGARHRLVLHNVGFADRGFFG----CETPD 2063
Query: 721 --TEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVK 754
T+ ++ VE + R + ++ E ++G T+ V+
Sbjct: 2064 DKTQAKLTVEMRQVRLVRGLQAVEAREQGTATMEVQ 2099
Score = 100 bits (248), Expect = 1e-20
Identities = 72/266 (27%), Positives = 112/266 (42%), Gaps = 34/266 (12%)
Query: 383 LTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEK 442
+ V+L+ D + W ++G Q + ++ G TLT+S D G
Sbjct: 2096 MEVQLSHADVDGSWTRDGLRFQQGPTCHLAVR-GPMHTLTLSGLRPEDSGLMVFKAEGVH 2154
Query: 443 CSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFK-- 500
S L V E PV +RPL+D + ++V ECE+S V+WLKDGVEL +T
Sbjct: 2155 TSARLVVTELPVSFSRPLQDVVTTEKEKVTLECELSRPNVDVRWLKDGVELRAGKTMAIA 2214
Query: 501 ----------YR---------------------FKKDGQRHHLIINEAMLEDAGHYALCT 529
YR K G+ + LI + EDAG
Sbjct: 2215 AQGACRSLTIYRCEFADQGVYVCDAHDAQSSASVKVQGRTYTLIYRRVLAEDAGEIQFVA 2274
Query: 530 SGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSR 589
++ A+L V+E + + + + D + K + V +C+VS + + W K +EL P +
Sbjct: 2275 ENAESRAQLRVKELPVTLVRPLRDKIAMEKHRGVLECQVSRASAQVRWFKGSQELQPGPK 2334
Query: 590 IKVSHIGRVHKLTIDDVTPADEADYS 615
++ G KL I DV DE Y+
Sbjct: 2335 YELVSDGLYRKLIISDVHAEDEDTYT 2360
Score = 100 bits (248), Expect = 1e-20
Identities = 81/269 (30%), Positives = 116/269 (43%), Gaps = 19/269 (7%)
Query: 347 GMLKRLKGMRRDEKKSTAFQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQMS 406
G+ KRLK M E +S +F+ L+ E A A W G+ + S
Sbjct: 2737 GITKRLKTMEVLEGESCSFE--------------CVLSHESASDPA--MWTVGGKTVG-S 2779
Query: 407 GSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCSTELFVKEPPVLITRPLEDQLVM 466
S++ G K L + + + +D V G L V+E P I +PLEDQ V
Sbjct: 2780 SSRFQATRQGRKYILVVREAAPSDAGEVVFSVRGLTSKASLIVRERPAAIIKPLEDQWVA 2839
Query: 467 VGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYA 526
G+ VE CE+S G V WLKD + + + KY +G L+I A L+DAG Y
Sbjct: 2840 PGEDVELRCELSRAGTPVHWLKDRKAIRKSQ--KYDVVCEGTMAMLVIRGASLKDAGEYT 2897
Query: 527 LCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVP 586
++ A L V+EK + + +L V K AVF C+ W K EL
Sbjct: 2898 CEVEASKSTASLHVEEKANCFTEELTNLQVEEKGTAVFTCKTEHPAATVTWRKGLLELRA 2957
Query: 587 DSRIKVSHIGRVHKLTIDDVTPADEADYS 615
+ + S G +LTI + AD Y+
Sbjct: 2958 SGKHQPSQEGLTLRLTISALEKADSDTYT 2986
Score = 99.0 bits (245), Expect = 3e-20
Identities = 78/274 (28%), Positives = 117/274 (42%), Gaps = 6/274 (2%)
Query: 365 FQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTIS 424
F++ L+ + Q +G L EL++ A V W K G ++Q +G + G L +
Sbjct: 3892 FREPLQ-SLQAEEGSTATLQCELSEPTATVVWSKGGLQLQANGRREP-RLQGCTAELVLQ 3949
Query: 425 QCSLADDAAYQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQV 484
D Y C G + S L V PV R L+ Q V G CE+S GA V
Sbjct: 3950 DLQREDTGEYTCTCGSQATSATLTVTAAPVRFLRELQHQEVDEGGTAHLCCELSRAGASV 4009
Query: 485 KWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKK 544
+W K ++L KY+ +DG L++ EDAG Y T Q++A L V+ +
Sbjct: 4010 EWRKGSLQLF--PCAKYQMVQDGAAAELLVRGVEQEDAGDYTCDTGHTQSMASLSVRVPR 4067
Query: 545 LEVYQSIADLMVGAKDQAVFKCEVSDENVRGV--WLKNGKELVPDSRIKVSHIGRVHKLT 602
+ + L D A C++SD V WLK G EL + ++ G +L
Sbjct: 4068 PKFKTRLQSLEQETGDIARLCCQLSDAESGAVVQWLKEGVELHAGPKYEMRSQGATRELL 4127
Query: 603 IDDVTPADEADYSFVPEGFACNLSAKLHFMEVKI 636
I + D +Y+ V G S ++ EV I
Sbjct: 4128 IHQLEAKDTGEYACVTGGQKTAASLRVTEPEVTI 4161
Score = 97.8 bits (242), Expect = 6e-20
Identities = 74/266 (27%), Positives = 114/266 (42%), Gaps = 9/266 (3%)
Query: 382 RLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGE 441
+L EL+D A V WLK+G+ + G KY ++ +R L + + D Y+CV G
Sbjct: 725 QLLAELSDQAAAVTWLKDGRTLS-PGPKYEVQASAGRRVLLVRDVARDDAGLYECVSRGG 783
Query: 442 KCSTELFVKEPPVLITRPLEDQLV--MVGQRVEFECEVSEEGAQVKWLKDGVELTREETF 499
+ + +L V+ + + + V + G +FECE SE V W KDG+EL
Sbjct: 784 RIAYQLSVQGLARFLHKDMAGSCVDAVAGGPAQFECETSEAHVHVHWYKDGMELGHSGE- 842
Query: 500 KYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKL---EVYQSIADLMV 556
++ + G RH L+ +D G Y+ L V E K+ + + L
Sbjct: 843 RFLQEDVGTRHRLVAATVTRQDEGTYSCRVGEDSVDFRLRVSEPKVVFAKEQLARRKLQA 902
Query: 557 GAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSF 616
A A CEV+ W K+GK+L S++ + G +L + AD +YS
Sbjct: 903 EAGASATLSCEVAQAQTEVTWYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEYSC 962
Query: 617 VPEGFACNLSAKLHFMEVKIDFVPRQ 642
E LS L E K+ F Q
Sbjct: 963 --EAGGQRLSFHLDVKEPKVVFAKDQ 986
Score = 92.8 bits (229), Expect = 2e-18
Identities = 98/377 (25%), Positives = 145/377 (38%), Gaps = 53/377 (14%)
Query: 395 KWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCSTELFVKEPPV 454
KWL G+ + +G E G L + + VG + S L V + PV
Sbjct: 2411 KWLL-GKTVLQAGGNVGLEQEGTVHRLMLRRTCSTMTGPVHFTVGKSRSSARLVVSDIPV 2469
Query: 455 LITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLII 514
++TRPLE + Q V C+ V+W KD L+ E FK +GQ L I
Sbjct: 2470 VLTRPLEPKTGRELQSVVLSCDFRPAPKAVQWYKDDTPLSPSEKFKMSL--EGQMAELRI 2527
Query: 515 NEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDENVR 574
M DAG Y + E+ V+ +++ V + D + A F CE+S E+
Sbjct: 2528 LRLMPADAGVYRCQAGSAHSSTEVTVEAREVTVTGPLQDAEATEEGWASFSCELSHEDEE 2587
Query: 575 GVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEV 634
W NG L DS ++SH GR H L + + AD + SA+L EV
Sbjct: 2588 VEWSLNGMPLYNDSFHEISHKGRRHTLVLKSIQRADAGIVR--ASSLKVSTSARL---EV 2642
Query: 635 KIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAP 694
++ P + L + D + L L +S DP V+W+K Q
Sbjct: 2643 RV-------KPVVFL----KALDDLSAEERGTLALQCEVS-DPEAHVVWRKDGVQ----- 2685
Query: 695 ARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVK 754
G SD++ F + T R + V ED G+YT
Sbjct: 2686 ----------LGPSDKYDF-------------LHTAGTRGL-VVHDVSPEDAGLYTC--- 2718
Query: 755 NPVGEDQVNLTVKVIDV 771
VG ++ V+V D+
Sbjct: 2719 -HVGSEETRARVRVHDL 2734
Score = 92.4 bits (228), Expect = 2e-18
Identities = 67/267 (25%), Positives = 116/267 (43%), Gaps = 11/267 (4%)
Query: 391 DAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCSTELFVK 450
D V W ++G +Q S K+ GA +LTIS L D G S L V+
Sbjct: 1926 DVAVVWFRDGALLQPS-EKFAISQSGASHSLTISDLVLEDAGQITVEAEGASSSAALRVR 1984
Query: 451 EPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKKDGQRH 510
E PVL + LE Q V V E E++ +++W ++ L + + +G RH
Sbjct: 1985 EAPVLFKKKLEPQTVEERSSVTLEVELTRPWPELRWTRNATALAPGKNVEIH--AEGARH 2042
Query: 511 HLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSD 570
L+++ D G + T + A+L V+ +++ + + + + + A + ++S
Sbjct: 2043 RLVLHNVGFADRGFFGCETPDDKTQAKLTVEMRQVRLVRGLQAVEAREQGTATMEVQLSH 2102
Query: 571 ENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLH 630
+V G W ++G ++ G +H LT+ + P D F EG + SA+L
Sbjct: 2103 ADVDGSWTRDGLRFQQGPTCHLAVRGPMHTLTLSGLRPEDSGLMVFKAEG--VHTSARLV 2160
Query: 631 FMEVKIDF------VPRQEPPKIHLDC 651
E+ + F V E K+ L+C
Sbjct: 2161 VTELPVSFSRPLQDVVTTEKEKVTLEC 2187
Score = 91.7 bits (226), Expect = 4e-18
Identities = 66/225 (29%), Positives = 95/225 (42%), Gaps = 5/225 (2%)
Query: 392 AEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCSTELFVKE 451
A V+W K G E G +Y G + L I S+AD Y CV G E+ S L V+
Sbjct: 3829 APVEWRK-GSETLRGGDRYSLRQDGTRCELQIHGLSVADTGEYSCVCGQERTSATLTVRA 3887
Query: 452 PPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKKDGQRHH 511
P + PL+ G +CE+SE A V W K G++L + R + G
Sbjct: 3888 PQPVFREPLQSLQAEEGSTATLQCELSEPTATVVWSKGGLQLQANGRREPRLQ--GCTAE 3945
Query: 512 LIINEAMLEDAGHYALCTSGGQAL-AELIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSD 570
L++ + ED G Y CT G QA A L V + + + V A CE+S
Sbjct: 3946 LVLQDLQREDTGEYT-CTCGSQATSATLTVTAAPVRFLRELQHQEVDEGGTAHLCCELSR 4004
Query: 571 ENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYS 615
W K +L P ++ ++ G +L + V D DY+
Sbjct: 4005 AGASVEWRKGSLQLFPCAKYQMVQDGAAAELLVRGVEQEDAGDYT 4049
Score = 88.6 bits (218), Expect = 3e-17
Identities = 112/508 (22%), Positives = 186/508 (36%), Gaps = 63/508 (12%)
Query: 394 VKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCSTELFVKEPP 453
V+W G +Q + + G TL + + D +G S +L V+ P
Sbjct: 4190 VQWCLQGLPLQSNEVTEVAVRDGRIHTLRLKGVTPEDAGTVSFHLGNHASSAQLTVRAPE 4249
Query: 454 VLITRPLEDQLVMVGQRVEFECEVSE-EGAQVKWLKDGVELTREETFKYRFKKDGQRHHL 512
V I PL+D + GQ F+C +S G + +W GV L E ++ G H L
Sbjct: 4250 VTILEPLQDVQLSEGQDASFQCRLSRASGQEARWALGGVPLQANEMNDITVEQ-GTLHLL 4308
Query: 513 IINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDEN 572
+++ LEDAG + + A+L V K V + + ++ +A+F+C++S
Sbjct: 4309 TLHKVTLEDAGTVSFHVGTCSSEAQLKVTAKNT-VVRGLENVEALEGGEALFECQLSQPE 4367
Query: 573 VRG-VWLKNGKELVPDSRIKVSHI--GRVHKLTIDDVTPADEADYSFVPEGFACNLSAKL 629
V WL + + + +V G H L + ++ P D +F+ + +
Sbjct: 4368 VAAHTWLLDDEPVHTSENAEVVFFENGLRHLLLLKNLRPQDSCRVTFLAGDMVTSAFLTV 4427
Query: 630 HFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPIS-GDPAPTVIWQKAIT 688
++I EP K V AG + +S P W
Sbjct: 4428 RGWRLEI-----LEPLK-----------NAAVRAGAQACFTCTLSEAVPVGEASWYI--- 4468
Query: 689 QGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGV 748
N A +P D +W V + A+ G
Sbjct: 4469 --NGAAVQP---------DDSDWT--------------VTADGSHHALLLRSAQPHHAGE 4503
Query: 749 YTVTVKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYIL 808
T ++ V ++ V+ +PD P ++ + T+ W P DGG + GY +
Sbjct: 4504 VTFACRDAVASARLT----VLGLPDPPEDAEVVARSSHTVTLSWAAPMSDGGGGLCGYRV 4559
Query: 809 ERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQ------ 862
E K+ + +W RL +L+ + G Y RV AV +G P Q
Sbjct: 4560 EVKEGATGQW-RLCHELVPGPECVVDGLAPGETYRFRVAAVGPVGAGEPVHLPQTVRLAE 4618
Query: 863 PFMPIGP-PSEPTHLAVEDVSDTTVSLK 889
P P+ P PS P V D ++ L+
Sbjct: 4619 PPKPVPPQPSAPESRQVAAGEDVSLELE 4646
Score = 87.4 bits (215), Expect = 8e-17
Identities = 139/653 (21%), Positives = 227/653 (34%), Gaps = 86/653 (13%)
Query: 7 KPVSAFSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYG-LATEGTRHT 65
KPV F K + + E V W++ G + S+KY L T GTR
Sbjct: 2645 KPV-VFLKALDDLSAEERGTLALQCEVSDPEAHVVWRKDGVQLGPSDKYDFLHTAGTRG- 2702
Query: 66 LTVREVGPADQGSYAVIAGSSKVKFDLKVIEAEKAEPMLAPAPAPAEATGAPGEAPAPAA 125
L V +V P D G Y GS + + ++V + E E
Sbjct: 2703 LVVHDVSPEDAGLYTCHVGSEETRARVRVHDLHVGITKRLKTMEVLEGESCSFECVLSHE 2762
Query: 126 ELGESAPSPKGSSSAALNGPTPGAPDDPIGLFVMR---PQD-GEVTVG-----GSITFSA 176
+ A G + + + V+R P D GEV +
Sbjct: 2763 SASDPAMWTVGGKTVGSSSRFQATRQGRKYILVVREAAPSDAGEVVFSVRGLTSKASLIV 2822
Query: 177 RVAGASLLKPPVVKWFK-GKWVDLSSKVGQH------------LQLHDSYDRASKVYLFE 223
R A+++KP +W G+ V+L ++ + ++ YD + +
Sbjct: 2823 RERPAAIIKPLEDQWVAPGEDVELRCELSRAGTPVHWLKDRKAIRKSQKYDVVCEGTMAM 2882
Query: 224 LHITDAQPAFTGSYRCEVSTKDKFDCSNFNLTVHEAMGTGDLDLLSAFRRTSLAGGGRRI 283
L I A G Y CEV S +L V E +L +
Sbjct: 2883 LVIRGASLKDAGEYTCEVEASK----STASLHVEEKANCFTEELTNL------------- 2925
Query: 284 SDSHEDTGILDFSSLLKKRDSFRTPRDSKLEAPAEEDVWE--ILRQAPPSEYERIAFQYG 341
E+ G F+ K E PA W +L +++ Q G
Sbjct: 2926 --QVEEKGTAVFTC--------------KTEHPAATVTWRKGLLELRASGKHQ--PSQEG 2967
Query: 342 VTDLRGMLKRLKGMRRDEKKSTAFQKKLEPAYQVSKGHKIRLTVELADHDAE-------- 393
+T LR + L+ D Q + A + +G ++ + +L D D +
Sbjct: 2968 LT-LRLTISALEKADSDTYTCDIGQAQSR-AQLLVQGRRVHIIEDLEDVDVQEGSSATFR 3025
Query: 394 ----------VKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKC 443
V W + + + I G LT+ Q +L D G ++
Sbjct: 3026 CRISPANYEPVHWFLDKTPLHANELNEIDAQPGGYHVLTLRQLALKDSGTIYFEAGDQRA 3085
Query: 444 STELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRF 503
S L V E P + +R L D + G+ + CE S V W KDG L + + +
Sbjct: 3086 SAALRVTEKPSVFSRELTDATITEGEDLTLVCETSTCDIPVCWTKDGKTL--RGSARCQL 3143
Query: 504 KKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELI-VQEKKLEVYQSIADLMVGAKDQA 562
+G R L+I A L+D+G Y C +GG + ++ V + + +++ DL V A
Sbjct: 3144 SHEGHRAQLLITGATLQDSGRYK-CEAGGACSSSIVRVHARPVRFQEALKDLEVLEGGAA 3202
Query: 563 VFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYS 615
+C +S W L P + + G + +L + ++ P D YS
Sbjct: 3203 TLRCVLSSVAAPVKWCYGNNVLRPGDKYSLRQEGAMLELVVRNLRPQDSGRYS 3255
Score = 85.9 bits (211), Expect = 2e-16
Identities = 75/278 (26%), Positives = 112/278 (40%), Gaps = 4/278 (1%)
Query: 359 EKKSTAFQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAK 418
E+K+ F ++L KG + T + A V W K E++ SG K+ G
Sbjct: 2912 EEKANCFTEELTNLQVEEKGTAV-FTCKTEHPAATVTWRKGLLELRASG-KHQPSQEGLT 2969
Query: 419 RTLTISQCSLADDAAYQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVS 478
LTIS AD Y C +G + +L V+ V I LED V G F C +S
Sbjct: 2970 LRLTISALEKADSDTYTCDIGQAQSRAQLLVQGRRVHIIEDLEDVDVQEGSSATFRCRIS 3029
Query: 479 EEGAQ-VKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAE 537
+ V W D L E + + G H L + + L+D+G +A A
Sbjct: 3030 PANYEPVHWFLDKTPLHANELNEIDAQPGGY-HVLTLRQLALKDSGTIYFEAGDQRASAA 3088
Query: 538 LIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGR 597
L V EK + + D + + CE S ++ W K+GK L +R ++SH G
Sbjct: 3089 LRVTEKPSVFSRELTDATITEGEDLTLVCETSTCDIPVCWTKDGKTLRGSARCQLSHEGH 3148
Query: 598 VHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVK 635
+L I T D Y G + ++H V+
Sbjct: 3149 RAQLLITGATLQDSGRYKCEAGGACSSSIVRVHARPVR 3186
Score = 84.3 bits (207), Expect = 7e-16
Identities = 64/250 (25%), Positives = 104/250 (41%), Gaps = 4/250 (1%)
Query: 365 FQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTIS 424
F+KKLEP V + + L VEL E++W +N + G + GA+ L +
Sbjct: 1990 FKKKLEPQ-TVEERSSVTLEVELTRPWPELRWTRNATALA-PGKNVEIHAEGARHRLVLH 2047
Query: 425 QCSLADDAAYQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQV 484
AD + C +K +L V+ V + R L+ E ++S
Sbjct: 2048 NVGFADRGFFGCETPDDKTQAKLTVEMRQVRLVRGLQAVEAREQGTATMEVQLSHADVDG 2107
Query: 485 KWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKK 544
W +DG+ + T + G H L ++ ED+G G A L+V E
Sbjct: 2108 SWTRDGLRFQQGPTCHLAVR--GPMHTLTLSGLRPEDSGLMVFKAEGVHTSARLVVTELP 2165
Query: 545 LEVYQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTID 604
+ + + D++ K++ +CE+S NV WLK+G EL + ++ G LTI
Sbjct: 2166 VSFSRPLQDVVTTEKEKVTLECELSRPNVDVRWLKDGVELRAGKTMAIAAQGACRSLTIY 2225
Query: 605 DVTPADEADY 614
AD+ Y
Sbjct: 2226 RCEFADQGVY 2235
Score = 83.2 bits (204), Expect = 1e-15
Identities = 64/237 (27%), Positives = 99/237 (41%), Gaps = 4/237 (1%)
Query: 379 HKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVV 438
H+ L +++ A+V+W K QE+Q G KY S G R L IS D+ Y C
Sbjct: 2305 HRGVLECQVSRASAQVRWFKGSQELQ-PGPKYELVSDGLYRKLIISDVHAEDEDTYTCDA 2363
Query: 439 GGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQ-VKWLKDGVELTREE 497
G K S + FV+E + I R L+D VM FECE S + KWL L +
Sbjct: 2364 GDVKTSAQFFVEEQSITIVRGLQDVTVMEPAPAWFECETSIPSVRPPKWLLGKTVL--QA 2421
Query: 498 TFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVG 557
+++G H L++ G ++ A L+V + + + + +
Sbjct: 2422 GGNVGLEQEGTVHRLMLRRTCSTMTGPVHFTVGKSRSSARLVVSDIPVVLTRPLEPKTGR 2481
Query: 558 AKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADY 614
V C+ W K+ L P + K+S G++ +L I + PAD Y
Sbjct: 2482 ELQSVVLSCDFRPAPKAVQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADAGVY 2538
Score = 82.8 bits (203), Expect = 2e-15
Identities = 62/242 (25%), Positives = 105/242 (43%), Gaps = 5/242 (2%)
Query: 374 QVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAA 433
+ ++G L EL+ A V+W K G E G ++ G++ L I ++ D
Sbjct: 3724 EATEGDTATLWCELSKA-APVEWRK-GHETLRDGDRHSLRQDGSRCELQIRGLAVVDAGE 3781
Query: 434 YQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVEL 493
Y CV G E+ S L V+ P +++Q G +CE+S + A V+W K L
Sbjct: 3782 YSCVCGQERTSATLTVRALPARFIEDVKNQEAREGATAVLQCELS-KAAPVEWRKGSETL 3840
Query: 494 TREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIAD 553
+ +Y ++DG R L I+ + D G Y+ + A L V+ + + +
Sbjct: 3841 RGGD--RYSLRQDGTRCELQIHGLSVADTGEYSCVCGQERTSATLTVRAPQPVFREPLQS 3898
Query: 554 LMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEAD 613
L A +CE+S+ VW K G +L + R + G +L + D+ D +
Sbjct: 3899 LQAEEGSTATLQCELSEPTATVVWSKGGLQLQANGRREPRLQGCTAELVLQDLQREDTGE 3958
Query: 614 YS 615
Y+
Sbjct: 3959 YT 3960
Score = 80.9 bits (198), Expect = 7e-15
Identities = 67/249 (26%), Positives = 105/249 (42%), Gaps = 10/249 (4%)
Query: 375 VSKGHKIRLTVELA-DHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAA 433
V++G RL+ + + E W K+GQ + ++E L I C +D
Sbjct: 249 VTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGL 308
Query: 434 YQC----VVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKD 489
Y C +VG S + V+EP V + L+D V + F CEV + + W K+
Sbjct: 309 YTCTASNLVGQTYSSVLVVVREPAVPFKKRLQDLEVREKESATFLCEVPQPSTEAAWFKE 368
Query: 490 GVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCT-SGGQALAELIVQEKKLEVY 548
L + KY +++G L + +D Y T G + +AEL VQ L
Sbjct: 369 ETRLW--ASAKYGIEEEGTERRLTVRNVSADDDAVYICETPEGSRTVAELAVQGNLLRKL 426
Query: 549 QSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTP 608
+ VG D A+F E++ WL+N +E+V R+ +S G H LTI
Sbjct: 427 PRKTAVRVG--DTAMFCVELAVPVGPVHWLRNQEEVVAGGRVAISAEGTRHTLTISQCCL 484
Query: 609 ADEADYSFV 617
D +F+
Sbjct: 485 EDVGQVAFM 493
Score = 79.7 bits (195), Expect = 2e-14
Identities = 139/619 (22%), Positives = 230/619 (37%), Gaps = 121/619 (19%)
Query: 465 VMVGQRVEFECEVS-EEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLI-INEAMLEDA 522
V G+ C V+ E + W KDG +T E ++ +D Q + ++ I D
Sbjct: 249 VTEGKHARLSCYVTGEPKPETVWKKDGQLVT--EGRRHVVYEDAQENFVLKILFCKQSDR 306
Query: 523 GHYALCTSG--GQALAEL--IVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDENVRGVWL 578
G Y S GQ + + +V+E + + + DL V K+ A F CEV + W
Sbjct: 307 GLYTCTASNLVGQTYSSVLVVVREPAVPFKKRLQDLEVREKESATFLCEVPQPSTEAAWF 366
Query: 579 KNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSF-VPEGFACNLSAKLHFMEVKID 637
K L ++ + G +LT+ +V+ D+A Y PEG S + + V+ +
Sbjct: 367 KEETRLWASAKYGIEEEGTERRLTVRNVSADDDAVYICETPEG-----SRTVAELAVQGN 421
Query: 638 FVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARP 697
+ R+ P K + R+ DT + + L VP+ P + Q+ + G
Sbjct: 422 LL-RKLPRKTAV----RVGDTAMFC----VELAVPVG--PVHWLRNQEEVVAG------- 463
Query: 698 APDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPV 757
GRV + R T+ ED G +
Sbjct: 464 -------------------------GRVAISAEGTRHTLTISQCCLEDVGQVAFMAGDCQ 498
Query: 758 GEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPIL--GYILERKKKKS 815
Q ++ P P + E S + W PP + G +P+ GY++E+KK +
Sbjct: 499 TSTQFCVSAPRKPPLQPPVDPVVKARMESSVILSWSPPPH-GERPVTIDGYLVEKKKLGT 557
Query: 816 YRWMRLN-FDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPT 874
Y W+R + + + + E ++ RV A+N+ G S P++
Sbjct: 558 YTWIRCHEAEWVATPELTVADVAEEGNFQFRVSALNSFGQS-------PYLEF---PGTV 607
Query: 875 HLAVEDVSDTTVSLKWRPPERVGA--GGLDGYSVEYCPEGCSEWVAALQGL--------- 923
HLA + T P + V A GG +SV+ EW Q L
Sbjct: 608 HLAPKLAVRT-------PLKAVQAVEGGEVTFSVDLTVASAGEWFLDGQALKASSVYEIH 660
Query: 924 ---TEHTSILVKDLPT---GARLLF-------RVRAHNMAGPGAPVTTTEPVTVQEILQR 970
T HT + ++++P GA+L F +R A PG +E+L R
Sbjct: 661 CDRTRHT-LTIREVPASLHGAQLKFVANGIESSIRMEVRAAPGLTANKPPAAAAREVLAR 719
Query: 971 PRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLA-GEEVSIRNSPTDTI 1029
+ E LL + VTW K+G+ L+ G + ++ S +
Sbjct: 720 ----------------LHEEAQLLAELSDQ-AAAVTWLKDGRTLSPGPKYEVQASAGRRV 762
Query: 1030 LFIRAARRVHSGTYQVTVR 1048
L +R R +G Y+ R
Sbjct: 763 LLVRDVARDDAGLYECVSR 781
Score = 78.2 bits (191), Expect = 5e-14
Identities = 143/648 (22%), Positives = 235/648 (36%), Gaps = 64/648 (9%)
Query: 6 KKPVSAFSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHT 65
+ P F + +S++ GS A + E V W +GG + A+ + +G
Sbjct: 3886 RAPQPVFREPLQSLQAEEGSTATLQCELSEPTATVVWSKGGLQLQANGRREPRLQGCTAE 3945
Query: 66 LTVREVGPADQGSYAVIAGSSKVKFDLKVIEAEKAEPMLAPAPAPAEATGAPGEAPAPAA 125
L ++++ D G Y GS L V A L G +
Sbjct: 3946 LVLQDLQREDTGEYTCTCGSQATSATLTVTAAPVR--FLRELQHQEVDEGGTAHLCCELS 4003
Query: 126 ELGESAPSPKGSSS----AALNGPTPGAPDDPIGLFVMRPQDGEVTVGGSITFSARVAGA 181
G S KGS A GA + + V + G+ T T S
Sbjct: 4004 RAGASVEWRKGSLQLFPCAKYQMVQDGAAAELLVRGVEQEDAGDYTCDTGHTQSMASLSV 4063
Query: 182 SLLKPPVVKWFKGKWVDLSSKVGQHL----QLHDSYDRASKVYLFELHITDAQPAFTGSY 237
+ +P FK + L + G QL D+ A +L E A P +
Sbjct: 4064 RVPRPK----FKTRLQSLEQETGDIARLCCQLSDAESGAVVQWLKEGVELHAGPKY--EM 4117
Query: 238 RCEVSTKDKFDCSNFNLTVH--EAMGTGDLDLLSAFRRTSLAGGGRRISDSHEDT--GIL 293
R + +T++ L +H EA TG+ ++ ++T+ + R+++ G++
Sbjct: 4118 RSQGATRE--------LLIHQLEAKDTGEYACVTGGQKTAAS---LRVTEPEVTIVRGLV 4166
Query: 294 DFSSLLKKRDSFRTPRDSKLEAPAEEDVWEILRQAPPSEYERIAFQYGVTDLRGMLKRLK 353
D + F ++ V L+ P E + V D R RLK
Sbjct: 4167 DAEVTADEDVEF----SCEVSRAGATGVQWCLQGLPLQSNE--VTEVAVRDGRIHTLRLK 4220
Query: 354 GMRRDEKKSTAFQKK-----------------LEPAY--QVSKGHKIRLTVELADHDA-E 393
G+ ++ + +F LEP Q+S+G L+ E
Sbjct: 4221 GVTPEDAGTVSFHLGNHASSAQLTVRAPEVTILEPLQDVQLSEGQDASFQCRLSRASGQE 4280
Query: 394 VKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCSTELFVKEPP 453
+W G +Q + I G LT+ + +L D VG CS+E +K
Sbjct: 4281 ARWALGGVPLQANEMNDITVEQGTLHLLTLHKVTLEDAGTVSFHVG--TCSSEAQLKVTA 4338
Query: 454 V-LITRPLEDQLVMVGQRVEFECEVSE-EGAQVKWLKDGVELTREETFKYRFKKDGQRHH 511
+ R LE+ + G FEC++S+ E A WL D + E + F ++G RH
Sbjct: 4339 KNTVVRGLENVEALEGGEALFECQLSQPEVAAHTWLLDDEPVHTSENAEVVFFENGLRHL 4398
Query: 512 LIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDE 571
L++ +D+ A L V+ +LE+ + + + V A QA F C +S+
Sbjct: 4399 LLLKNLRPQDSCRVTFLAGDMVTSAFLTVRGWRLEILEPLKNAAVRAGAQACFTCTLSEA 4458
Query: 572 NVRG--VWLKNGKELVP-DSRIKVSHIGRVHKLTIDDVTPADEADYSF 616
G W NG + P DS V+ G H L + P + +F
Sbjct: 4459 VPVGEASWYINGAAVQPDDSDWTVTADGSHHALLLRSAQPHHAGEVTF 4506
Score = 76.6 bits (187), Expect = 1e-13
Identities = 153/669 (22%), Positives = 246/669 (36%), Gaps = 122/669 (18%)
Query: 6 KKPVSAFSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHT 65
++ + F+++ +++V AVF +TE V W++G ++ AS K+ + EG
Sbjct: 2912 EEKANCFTEELTNLQVEEKGTAVFTCKTEHPAATVTWRKGLLELRASGKHQPSQEGLTLR 2971
Query: 66 LTVREVGPADQGSYAVIAGSSKVKF----------------DLKVIEAEKAEPMLAPAPA 109
LT+ + AD +Y G ++ + D+ V E A +PA
Sbjct: 2972 LTISALEKADSDTYTCDIGQAQSRAQLLVQGRRVHIIEDLEDVDVQEGSSATFRCRISPA 3031
Query: 110 PAEATG-APGEAPAPAAELGESAPSPKG------------------------SSSAALNG 144
E + P A EL E P G +SAAL
Sbjct: 3032 NYEPVHWFLDKTPLHANELNEIDAQPGGYHVLTLRQLALKDSGTIYFEAGDQRASAALR- 3090
Query: 145 PTPGAPDDPIGLFVMRPQDGEVTVGGSITFSARVAGASLLKPPVVKWFKGKWVDLSSKVG 204
+ P +F D +T G +T V S PV GK + S++
Sbjct: 3091 ----VTEKP-SVFSRELTDATITEGEDLTL---VCETSTCDIPVCWTKDGKTLRGSARC- 3141
Query: 205 QHLQLHDSYDRASKVYLFELHITDAQPAFTGSYRCEVSTKDKFDCSNFNLTVH------- 257
QL RA +L IT A +G Y+CE CS+ + VH
Sbjct: 3142 ---QLSHEGHRA------QLLITGATLQDSGRYKCEAGGA----CSSSIVRVHARPVRFQ 3188
Query: 258 EAMGTGDLDLL---SAFRRTSLAGGGRRISDSHEDTGILDFSSLLKKRDSFRTPRDSKLE 314
EA+ DL++L +A R L+ + + + ++L+ D + ++ +
Sbjct: 3189 EALK--DLEVLEGGAATLRCVLSSVAAPVKWCYGN-------NVLRPGDKYSLRQEGAM- 3238
Query: 315 APAEEDVWEILRQAPPSEYERIAFQYGVTDLRGMLKRLKGMRRDEKKSTAFQKKLEPAYQ 374
+ ++R P + R + +G D+ S PA
Sbjct: 3239 ------LELVVRNLRPQDSGRYSCSFG----------------DQTTSATLTVTALPAQF 3276
Query: 375 VSK--------GHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQC 426
+ K G L EL+ A V+W K G E G +Y GA L I
Sbjct: 3277 IGKLRNKEATEGATATLRCELSKA-APVEWRK-GSETLRDGDRYCLRQDGAMCELQIRGL 3334
Query: 427 SLADDAAYQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKW 486
++ D A Y CV G E+ S L ++ P L Q + G CE+S + A V+W
Sbjct: 3335 AMVDAAEYSCVCGEERTSASLTIRPMPAHFIGRLRHQESIEGATATLRCELS-KAAPVEW 3393
Query: 487 LKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLE 546
K G E R+ ++ ++DG L I + DAG Y+ + A L V+ +
Sbjct: 3394 RK-GRESLRDGD-RHSLRQDGAVCELQICGLAVADAGEYSCVCGEERTSATLTVKALPAK 3451
Query: 547 VYQSIADLMVGAKDQAVFKCEVSDENVRGV-WLKNGKELVPDSRIKVSHIGRVHKLTIDD 605
+ + + A+ CE+S V V W K + L R + G +L I
Sbjct: 3452 FTEGLRNEEAVEGATAMLWCELS--KVAPVEWRKGPENLRDGDRYILRQEGTRCELQICG 3509
Query: 606 VTPADEADY 614
+ AD +Y
Sbjct: 3510 LAMADAGEY 3518
Score = 76.6 bits (187), Expect = 1e-13
Identities = 65/226 (28%), Positives = 96/226 (42%), Gaps = 5/226 (2%)
Query: 392 AEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCSTELFVKE 451
A V+W K G E G +Y G K L I ++AD Y CV G E+ S L V+
Sbjct: 3565 APVEWRK-GSETLRDGDRYSLRQDGTKCELQIRGLAMADTGEYSCVCGQERTSAMLTVRA 3623
Query: 452 PPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKKDGQRHH 511
P+ T L ++ G CE+S+ A V+W K G E R+ ++ ++DG R
Sbjct: 3624 LPIKFTEGLRNEEATEGATAVLRCELSKM-APVEWWK-GHETLRDGD-RHSLRQDGARCE 3680
Query: 512 LIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDE 571
L I + EDAG Y + A L V+ + + + + D A CE+S +
Sbjct: 3681 LQIRGLVAEDAGEYLCMCGKERTSAMLTVRAMPSKFIEGLRNEEATEGDTATLWCELS-K 3739
Query: 572 NVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFV 617
W K + L R + G +L I + D +YS V
Sbjct: 3740 AAPVEWRKGHETLRDGDRHSLRQDGSRCELQIRGLAVVDAGEYSCV 3785
Score = 70.1 bits (170), Expect = 1e-11
Identities = 58/223 (26%), Positives = 95/223 (42%), Gaps = 5/223 (2%)
Query: 392 AEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCSTELFVKE 451
A V+W K G E G +YI G + L I ++AD Y CV G E+ S L ++
Sbjct: 3477 APVEWRK-GPENLRDGDRYILRQEGTRCELQICGLAMADAGEYLCVCGQERTSATLTIRA 3535
Query: 452 PPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKKDGQRHH 511
P +++Q G +CE++ A V+W K G E R+ +Y ++DG +
Sbjct: 3536 LPARFIEDVKNQEAREGATAVLQCELN-SAAPVEWRK-GSETLRDGD-RYSLRQDGTKCE 3592
Query: 512 LIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDE 571
L I + D G Y+ + A L V+ ++ + + + AV +CE+S +
Sbjct: 3593 LQIRGLAMADTGEYSCVCGQERTSAMLTVRALPIKFTEGLRNEEATEGATAVLRCELS-K 3651
Query: 572 NVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADY 614
W K + L R + G +L I + D +Y
Sbjct: 3652 MAPVEWWKGHETLRDGDRHSLRQDGARCELQIRGLVAEDAGEY 3694
Score = 68.2 bits (165), Expect = 5e-11
Identities = 126/582 (21%), Positives = 203/582 (34%), Gaps = 81/582 (13%)
Query: 1 MPEPGKKPVSAFSKKPRSVEVAAGSPAVFEAE-TERAGVKVRWQRGGSDISASNKYGLAT 59
M +P F +P++ V+ G A + +V W++ ++A ++ LA
Sbjct: 1 MDQPQFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQ 60
Query: 60 EGTRHTLTVREVGPADQGSYAVIA----GSSKVKFDLKVIEAEKAEPMLAP--APAPAEA 113
+G + LT+ ++ D G Y A G + L+V +AE A AP P
Sbjct: 61 DGDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQV-DAEAACAEQAPHFLLRPTSI 119
Query: 114 TGAPGEAPAPAAELGESAPSPKGSSSAALNGPTPGAPDDP------------IGLFVMRP 161
G +G S P+ + S + +G G PD P + + RP
Sbjct: 120 RVREGSEATFRCRVGGS---PRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARP 176
Query: 162 QDGEV-TVGGSITFSARVAGASLLKPPVVKWFKGKWVDLSSKVGQHLQLHDSYDRASKVY 220
+DG V A A A+L+ + ++ + HLQ RA
Sbjct: 177 RDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRREAMRAEGA- 235
Query: 221 LFELHITDAQPAFTGSYRCEVSTKD--KFDCSNFNLTVHEAMGTGDLDLLSAFRRTSLAG 278
A P TG+ C V+ + C E + D L++ RR
Sbjct: 236 -------PASPPSTGTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRR----- 283
Query: 279 GGRRISDSHEDTGILDFSSLLKKRDSFRTPRDSKLEAPAEEDVWEILRQAPPSEYERIAF 338
+ + ++ +L + T S L V ++R+ + F
Sbjct: 284 --HVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVREPA------VPF 335
Query: 339 QYGVTDLRGMLKRLKGMRRDEKKSTAFQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLK 398
+ KRL+ + EK+S F E+ E W K
Sbjct: 336 K----------KRLQDLEVREKESATF------------------LCEVPQPSTEAAWFK 367
Query: 399 NGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVG-GEKCSTELFVKEPPVLIT 457
+ S +KY E G +R LT+ S DDA Y C G + EL V+ L+
Sbjct: 368 EETRLWAS-AKYGIEEEGTERRLTVRNVSADDDAVYICETPEGSRTVAELAVQGN--LLR 424
Query: 458 RPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEA 517
+ V VG F E++ V WL++ E+ + +G RH L I++
Sbjct: 425 KLPRKTAVRVGDTAMFCVELAVPVGPVHWLRNQEEVVAGG--RVAISAEGTRHTLTISQC 482
Query: 518 MLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAK 559
LED G A Q + V + Q D +V A+
Sbjct: 483 CLEDVGQVAFMAGDCQTSTQFCVSAPRKPPLQPPVDPVVKAR 524
Score = 68.2 bits (165), Expect = 5e-11
Identities = 73/294 (24%), Positives = 116/294 (39%), Gaps = 22/294 (7%)
Query: 392 AEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCSTELFVKE 451
A V+W K G E G ++ GA+ L I D Y C+ G E+ S L V+
Sbjct: 3653 APVEWWK-GHETLRDGDRHSLRQDGARCELQIRGLVAEDAGEYLCMCGKERTSAMLTVRA 3711
Query: 452 PPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKKDGQRHH 511
P L ++ G CE+S+ A V+W K G E R+ ++ ++DG R
Sbjct: 3712 MPSKFIEGLRNEEATEGDTATLWCELSK-AAPVEWRK-GHETLRDGD-RHSLRQDGSRCE 3768
Query: 512 LIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDE 571
L I + DAG Y+ + A L V+ + + + AV +CE+S +
Sbjct: 3769 LQIRGLAVVDAGEYSCVCGQERTSATLTVRALPARFIEDVKNQEAREGATAVLQCELS-K 3827
Query: 572 NVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHF 631
W K + L R + G +L I ++ AD +YS V C
Sbjct: 3828 AAPVEWRKGSETLRGGDRYSLRQDGTRCELQIHGLSVADTGEYSCV-----CGQERTSAT 3882
Query: 632 MEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQK 685
+ V+ +EP + ++ G+ L +S +P TV+W K
Sbjct: 3883 LTVRAPQPVFREPLQ-----------SLQAEEGSTATLQCELS-EPTATVVWSK 3924
Score = 62.8 bits (151), Expect = 2e-09
Identities = 66/261 (25%), Positives = 98/261 (37%), Gaps = 6/261 (2%)
Query: 357 RDEKKSTAFQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIG 416
R + FQ+ L+ +V +G L L+ A VKW G + G KY G
Sbjct: 3179 RVHARPVRFQEALKDL-EVLEGGAATLRCVLSSVAAPVKWCY-GNNVLRPGDKYSLRQEG 3236
Query: 417 AKRTLTISQCSLADDAAYQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECE 476
A L + D Y C G + S L V P L ++ G CE
Sbjct: 3237 AMLELVVRNLRPQDSGRYSCSFGDQTTSATLTVTALPAQFIGKLRNKEATEGATATLRCE 3296
Query: 477 VSEEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALA 536
+S + A V+W K G E R+ +Y ++DG L I + DA Y+ + A
Sbjct: 3297 LS-KAAPVEWRK-GSETLRDGD-RYCLRQDGAMCELQIRGLAMVDAAEYSCVCGEERTSA 3353
Query: 537 ELIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIG 596
L ++ + A +CE+S + W K + L R + G
Sbjct: 3354 SLTIRPMPAHFIGRLRHQESIEGATATLRCELS-KAAPVEWRKGRESLRDGDRHSLRQDG 3412
Query: 597 RVHKLTIDDVTPADEADYSFV 617
V +L I + AD +YS V
Sbjct: 3413 AVCELQICGLAVADAGEYSCV 3433
Score = 60.5 bits (145), Expect = 1e-08
Identities = 62/224 (27%), Positives = 84/224 (37%), Gaps = 19/224 (8%)
Query: 1030 LFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPP 1089
L +R+A+ H+G R + A+ L V+ P PP+D V V L W P
Sbjct: 4491 LLLRSAQPHHAGEVTFACR----DAVASARLTVLGLPDPPEDAEVVARSSHTVTLSWAAP 4546
Query: 1090 QDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSD 1149
G L GY V+ + T +W E CVV L G Y FRV + VG
Sbjct: 4547 MSDGGGGLCGYRVEVKEGATGQWRLCHELVPGPECVVDGLAPGETYRFRVAAVGPVG--- 4603
Query: 1150 RAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPK 1209
EPV +P+ EPP P +R V AG L V +
Sbjct: 4604 ----AGEPVHLPQTVRLAEPP-------KPVPPQPSAPESRQVAAGEDVSLELEV-VAEA 4651
Query: 1210 PKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVC 1253
++ W K + RF + S+ L I+ D G Y C
Sbjct: 4652 GEVIWHKGMERIQPGGRFEVVSQGRQQMLVIKGFTAEDQGEYHC 4695
Score = 58.2 bits (139), Expect = 5e-08
Identities = 40/112 (35%), Positives = 51/112 (45%), Gaps = 4/112 (3%)
Query: 1161 PRPGITYEP-PNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGL 1219
P P + EP P+ D AP F L N+ V GY C V G P P + WFK+G
Sbjct: 5107 PAPVVPPEPLPSLLTSD--AAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGK 5164
Query: 1220 DLGEDARFRM-FSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
L ED + + +QG L I P D G+Y C A N G + + L V
Sbjct: 5165 LLEEDDHYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRV 5216
Score = 56.6 bits (135), Expect = 1e-07
Identities = 30/95 (31%), Positives = 44/95 (46%), Gaps = 2/95 (2%)
Query: 1181 PSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFS--KQGVLTL 1238
P F + + G A C + G+P P+I W+K+G L +F+ S + G+L L
Sbjct: 6108 PRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVL 6167
Query: 1239 EIRKPCPFDGGIYVCRATNLQGEARCECRLEVRVP 1273
IR D G+Y C N G AR L ++ P
Sbjct: 6168 VIRAASKEDLGLYECELVNRLGSARASAELRIQSP 6202
Score = 54.7 bits (130), Expect = 6e-07
Identities = 35/94 (37%), Positives = 44/94 (46%)
Query: 1177 FSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVL 1236
FS AP F V G A L C + G+P P++SW K+ + ARFR+ +
Sbjct: 6 FSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLY 65
Query: 1237 TLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
L I D G YVCRA N GEA L+V
Sbjct: 66 RLTILDLALGDSGQYVCRARNAIGEAFAAVGLQV 99
Score = 52.4 bits (124), Expect = 3e-06
Identities = 49/196 (25%), Positives = 79/196 (40%), Gaps = 19/196 (9%)
Query: 394 VKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGE--KCST--ELFV 449
+ W K+G+ +Q+ + E L + + D Y C CST ++ V
Sbjct: 6045 ISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMCFAASAAGNCSTLGKILV 6104
Query: 450 KEPPVLITRPLEDQLVMVGQRVEFECEVSEEGA---QVKWLKDGVELTREETFKYRFKKD 506
+ PP + + V G+ +F C + EGA Q++W KDG LT F+ +
Sbjct: 6105 QVPPRFVNKVRASPFV-EGEDAQFTCTI--EGAPYPQIRWYKDGALLTTGNKFQTLSEPR 6161
Query: 507 GQRHHLIINEAMLEDAGHYAL----CTSGGQALAELIVQEKKLEVYQSI--ADLMVGAKD 560
L+I A ED G Y +A AEL +Q L+ + L+ +D
Sbjct: 6162 SGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAVED 6221
Query: 561 QAVFKCEVSDENVRGV 576
+ E +D+ V V
Sbjct: 6222 TTL---ERADQEVTSV 6234
Score = 52.4 bits (124), Expect = 3e-06
Identities = 28/101 (27%), Positives = 46/101 (45%), Gaps = 2/101 (1%)
Query: 1172 YKALDFSEA--PSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRM 1229
Y+A+D A PS + + G TA + G P+P ++W+K+ + L + R
Sbjct: 6346 YQAIDTHTARPPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQ 6405
Query: 1230 FSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
+ +L +R D G+Y C A N G+ C+ L V
Sbjct: 6406 QQEGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLV 6446
Score = 51.6 bits (122), Expect = 5e-06
Identities = 36/94 (38%), Positives = 42/94 (44%), Gaps = 2/94 (2%)
Query: 1179 EAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGE--DARFRMFSKQGVL 1236
+AP F + V G A C V GSP+P +SW K+G LGE R R+
Sbjct: 108 QAPHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEAS 167
Query: 1237 TLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
L IR P DGG Y RA N G A L V
Sbjct: 168 ALRIRAARPRDGGTYEVRAENPLGAASAAAALVV 201
Score = 50.1 bits (118), Expect = 1e-05
Identities = 85/397 (21%), Positives = 141/397 (35%), Gaps = 81/397 (20%)
Query: 437 VVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGA-QVKWLKDGVELTR 495
VV E + L PV +T L++Q V G V F+C V+ + V+W KDG L
Sbjct: 5110 VVPPEPLPSLLTSDAAPVFLTE-LQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLL-- 5166
Query: 496 EETFKYRFKKDGQR-HHLIINEAMLEDAGHYALCTSGGQALA------------------ 536
EE Y +D Q H LII + D G Y ++
Sbjct: 5167 EEDDHYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTA 5226
Query: 537 ------------------------ELIVQEKKL-EVYQSIADLMVGAKDQ-AVFKCEVSD 570
E E +L +V + + DL V + A F+ +V
Sbjct: 5227 ADATESSSYFSAQGYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKG 5286
Query: 571 ENV-RGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADY-SFVPEGFACNLSAK 628
R W K+G+ L + I+++ +H L I VT D Y +++ S+
Sbjct: 5287 YPAPRLYWFKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSA 5346
Query: 629 LHFMEVKIDFVPRQEPPK-IHLD-CPGRIPDTIV---VVAGNKLRLDVPISGDPAPTVIW 683
+ V+ P ++P +H P R+ + V G+ + V + G P PTV W
Sbjct: 5347 R--LLVRGPDEPEEKPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHW 5404
Query: 684 QKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEK 743
+ + + PD P T V ++ + + +
Sbjct: 5405 LR--EEAERGVLWIGPDTPGYT---------------------VASSAQQHSLVLLDVGR 5441
Query: 744 EDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPKI 780
+ +G YT N G+ + ++ V +P K+
Sbjct: 5442 QHQGTYTCIASNAAGQALCSASLHVSGLPKVEEQEKV 5478
Score = 49.7 bits (117), Expect = 2e-05
Identities = 36/131 (27%), Positives = 53/131 (40%), Gaps = 8/131 (6%)
Query: 14 KKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGP 73
K PR V G A+F E V W R ++ A + ++ EGTRHTLT+ +
Sbjct: 425 KLPRKTAVRVGDTAMFCVELAVPVGPVHWLRNQEEVVAGGRVAISAEGTRHTLTISQCCL 484
Query: 74 ADQGSYAVIAGSSKVKFDLKVIEAEKAEPMLAPAPAPAEATGAPGEAPAPAAELGESAPS 133
D G A +AG + V K P L P P +A ++ + +P
Sbjct: 485 EDVGQVAFMAGDCQTSTQFCVSAPRK--PPLQPPVDPVV------KARMESSVILSWSPP 536
Query: 134 PKGSSSAALNG 144
P G ++G
Sbjct: 537 PHGERPVTIDG 547
Score = 49.7 bits (117), Expect = 2e-05
Identities = 34/99 (34%), Positives = 44/99 (44%), Gaps = 1/99 (1%)
Query: 1176 DFSEAPSFTQPLVNRSVIAGYT-AMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQG 1234
D + P + L + V G A V+G P P++ WFK+G L A RM K+
Sbjct: 5255 DEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIRMTDKKI 5314
Query: 1235 VLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVRVP 1273
+ TLEI D G Y +N G A RL VR P
Sbjct: 5315 LHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGP 5353
Score = 49.3 bits (116), Expect = 2e-05
Identities = 31/101 (30%), Positives = 45/101 (44%), Gaps = 1/101 (0%)
Query: 1174 ALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMF-SK 1232
AL P F + L + + G T L C V G+PKP ISW+K+G + D +
Sbjct: 6007 ALPVWRPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDP 6066
Query: 1233 QGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVRVP 1273
G L + D G Y+C A + G ++ V+VP
Sbjct: 6067 DGSCALILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVP 6107
Score = 48.9 bits (115), Expect = 3e-05
Identities = 48/166 (28%), Positives = 60/166 (36%), Gaps = 31/166 (18%)
Query: 856 RPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSE 915
R + AS +G P P V S TV+L W P G GGL GY VE +
Sbjct: 4509 RDAVASARLTVLGLPDPPEDAEVVARSSHTVTLSWAAPMSDGGGGLCGYRVEVKEGATGQ 4568
Query: 916 WVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQL 975
W L +V L G FRV A G G PV
Sbjct: 4569 W-RLCHELVPGPECVVDGLAPGETYRFRVAAVGPVGAGEPV------------------- 4608
Query: 976 PRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSI 1021
HL QT+ ++ EP + P P + Q AGE+VS+
Sbjct: 4609 --HLPQTV--RLAEPPKPVPPQPSAPESR-------QVAAGEDVSL 4643
Score = 47.8 bits (112), Expect = 7e-05
Identities = 74/311 (23%), Positives = 111/311 (35%), Gaps = 26/311 (8%)
Query: 987 VGEPVNLLIPFQGKPRPQVTWTKEGQPLA-GEEVSIRNSPTDTILFIRAARRVHSGTYQV 1045
VG+ L G P PQV+W K+ QP+A G + L I SG Y
Sbjct: 23 VGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDLALGDSGQYVC 82
Query: 1046 TVRIENMEDKATLVLQVVDKPS----------PPQDLRVTDAWGLNVALEWKPPQDVGNT 1095
R E A + LQV + + P +RV + G +
Sbjct: 83 RARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTSIRVRE--GSEATFRCRVGGSPRPA 140
Query: 1096 ELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGF-------- 1147
W ++ + V E + + +G + V ++N +G
Sbjct: 141 VSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAASAAAALV 200
Query: 1148 --SDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRS--VIAGYTAMLCCA 1203
SD A T P + + +A+ AP+ R+ V G A L C
Sbjct: 201 VDSDAADTASRPGTSTAALLAHLQRRREAMRAEGAPASPPSTGTRTCTVTEGKHARLSCY 260
Query: 1204 VRGSPKPKISWFKNGLDLGEDARFRMF-SKQGVLTLEIRKPCPFDGGIYVCRATNLQGEA 1262
V G PKP+ W K+G + E R ++ Q L+I D G+Y C A+NL G+
Sbjct: 261 VTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQT 320
Query: 1263 RCECRLEVRVP 1273
+ VR P
Sbjct: 321 YSSVLVVVREP 331
Score = 47.4 bits (111), Expect = 9e-05
Identities = 54/243 (22%), Positives = 89/243 (36%), Gaps = 50/243 (20%)
Query: 555 MVGAKDQAVFKCEVSDENVRGV-WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEAD 613
+V A C++ V W K+ + + +R +++ G +++LTI D+ D
Sbjct: 20 VVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDLALGDSGQ 79
Query: 614 Y-----SFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLR 668
Y + + E FA ++V + ++ P L P +I V G++
Sbjct: 80 YVCRARNAIGEAFAA------VGLQVDAEAACAEQAPHFLLR-----PTSIRVREGSEAT 128
Query: 669 LDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEG-RVRV 727
+ G P P V W K D + L E +G RVRV
Sbjct: 129 FRCRVGGSPRPAVSWSK----------------------------DGRRLGEPDGPRVRV 160
Query: 728 ETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDS 787
E + S + A D G Y V +NP+G + V D+ AA S G +
Sbjct: 161 EELGEASALRIRAARPRDGGTYEVRAENPLGAASAAAAL----VVDSDAADTASRPGTST 216
Query: 788 CTV 790
+
Sbjct: 217 AAL 219
Score = 46.6 bits (109), Expect = 2e-04
Identities = 23/83 (27%), Positives = 40/83 (48%), Gaps = 1/83 (1%)
Query: 12 FSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREV 71
F + ++ E G+ AV + E +A V W++G + ++Y L +GTR L + +
Sbjct: 3804 FIEDVKNQEAREGATAVLQCELSKAA-PVEWRKGSETLRGGDRYSLRQDGTRCELQIHGL 3862
Query: 72 GPADQGSYAVIAGSSKVKFDLKV 94
AD G Y+ + G + L V
Sbjct: 3863 SVADTGEYSCVCGQERTSATLTV 3885
Score = 44.7 bits (104), Expect = 6e-04
Identities = 23/83 (27%), Positives = 40/83 (48%), Gaps = 1/83 (1%)
Query: 12 FSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREV 71
F + ++ E G+ AV + E A V W++G + ++Y L +GT+ L +R +
Sbjct: 3540 FIEDVKNQEAREGATAVLQCELNSAA-PVEWRKGSETLRDGDRYSLRQDGTKCELQIRGL 3598
Query: 72 GPADQGSYAVIAGSSKVKFDLKV 94
AD G Y+ + G + L V
Sbjct: 3599 AMADTGEYSCVCGQERTSAMLTV 3621
Score = 44.3 bits (103), Expect = 8e-04
Identities = 54/229 (23%), Positives = 82/229 (35%), Gaps = 22/229 (9%)
Query: 976 PRHLRQTIQKKV--GEPVNLLIPFQGKPRPQVTWTKEGQPLAGE-----EVSIRNSPTDT 1028
P LR+ + V G+ V L +P Q TW+K+G PL +++N T
Sbjct: 7463 PTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLT 7522
Query: 1029 ILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKP 1088
IL + A G Y +V T VL+ ++PS + + + V L WKP
Sbjct: 7523 ILVVVAE---DLGVYTCSVSNALGTVTTTGVLRKAERPSSSPCPDIGEVYADGVLLVWKP 7579
Query: 1089 PQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFS 1148
+ G Y VQ + W T+ + +L G Y FR + G
Sbjct: 7580 VESYGPVT---YIVQ-CSLEGGSWTTLASDIFDCCYLTSKLSRGGTYTFRTACVSKAGMG 7635
Query: 1149 DRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYT 1197
P P + P++ A + QPL + A T
Sbjct: 7636 --------PYSSPSEQVLLGGPSHLASEEESQGRSAQPLPSTKTFAFQT 7676
Score = 43.5 bits (101), Expect = 0.001
Identities = 27/87 (31%), Positives = 39/87 (44%), Gaps = 1/87 (1%)
Query: 8 PVSAFSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLT 67
PVS FS+ + V E E R V VRW + G ++ A +A +G +LT
Sbjct: 2165 PVS-FSRPLQDVVTTEKEKVTLECELSRPNVDVRWLKDGVELRAGKTMAIAAQGACRSLT 2223
Query: 68 VREVGPADQGSYAVIAGSSKVKFDLKV 94
+ ADQG Y A ++ +KV
Sbjct: 2224 IYRCEFADQGVYVCDAHDAQSSASVKV 2250
Score = 42.4 bits (98), Expect = 0.003
Identities = 76/356 (21%), Positives = 128/356 (35%), Gaps = 45/356 (12%)
Query: 915 EWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRL- 973
+W+ L ++ ++ T RL+ R M GP TV + RL
Sbjct: 2411 KWLLGKTVLQAGGNVGLEQEGTVHRLMLRRTCSTMTGP-------VHFTVGKSRSSARLV 2463
Query: 974 --QLPRHLRQTIQKKVGEPV-NLLIPFQGKPRPQ-VTWTKEGQPLAGEEVSIRNSPTDTI 1029
+P L + ++ K G + ++++ +P P+ V W K+ PL+ E + S +
Sbjct: 2464 VSDIPVVLTRPLEPKTGRELQSVVLSCDFRPAPKAVQWYKDDTPLSPSE-KFKMSLEGQM 2522
Query: 1030 LFIRAARRV--HSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWK 1087
+R R + +G Y+ + + T+ + V P QD T+ + + E
Sbjct: 2523 AELRILRLMPADAGVYRCQAGSAHSSTEVTVEAREVTVTGPLQDAEATEEGWASFSCELS 2582
Query: 1088 PPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGF 1147
+ L G + + F + H R H +V + I S V
Sbjct: 2583 HEDEEVEWSLNGMPLYN------DSFHEISHKGRRHTLVLKSIQRADAGIVRASSLKVST 2636
Query: 1148 SDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGS 1207
S R +PV KALD A R +A L C V
Sbjct: 2637 SARLEVRVKPVVF-----------LKALDDLSAEE-------RGTLA-----LQCEV-SD 2672
Query: 1208 PKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEAR 1263
P+ + W K+G+ LG ++ G L + P D G+Y C + + AR
Sbjct: 2673 PEAHVVWRKDGVQLGPSDKYDFLHTAGTRGLVVHDVSPEDAGLYTCHVGSEETRAR 2728
Score = 42.0 bits (97), Expect = 0.004
Identities = 26/81 (32%), Positives = 40/81 (49%), Gaps = 5/81 (6%)
Query: 1194 AGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVC 1253
AG TAML C V P+ +++W+K+G L ++ RM K L +++ D G Y C
Sbjct: 1180 AGTTAMLSCEV-AQPQTEVTWYKDGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEYSC 1238
Query: 1254 RATNLQGEARCECRLEVRVPQ 1274
A G R +L + P+
Sbjct: 1239 EA----GGQRVSFQLHITEPK 1255
Score = 41.6 bits (96), Expect = 0.005
Identities = 24/83 (28%), Positives = 34/83 (40%)
Query: 12 FSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREV 71
F KK V S E E R ++RW R + ++ + EG RH L + V
Sbjct: 1990 FKKKLEPQTVEERSSVTLEVELTRPWPELRWTRNATALAPGKNVEIHAEGARHRLVLHNV 2049
Query: 72 GPADQGSYAVIAGSSKVKFDLKV 94
G AD+G + K + L V
Sbjct: 2050 GFADRGFFGCETPDDKTQAKLTV 2072
Score = 40.8 bits (94), Expect = 0.008
Identities = 26/90 (28%), Positives = 41/90 (45%), Gaps = 5/90 (5%)
Query: 18 SVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQG 77
+V G A F+ + V V W R G+ + S K+ ++ G H+LT+ ++ D G
Sbjct: 1907 TVVAEEGGEATFQCVVSPSDVAVVWFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAG 1966
Query: 78 SYAVIAGSSKVKFDLKVIEA-----EKAEP 102
V A + L+V EA +K EP
Sbjct: 1967 QITVEAEGASSSAALRVREAPVLFKKKLEP 1996
Score = 40.8 bits (94), Expect = 0.008
Identities = 23/85 (27%), Positives = 39/85 (45%), Gaps = 1/85 (1%)
Query: 1177 FSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSK-QGV 1235
+ AP+F + L + +V+ G + L C V P + +W K+G L +R + + +
Sbjct: 7459 WDRAPTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNF 7518
Query: 1236 LTLEIRKPCPFDGGIYVCRATNLQG 1260
L I D G+Y C +N G
Sbjct: 7519 QLLTILVVVAEDLGVYTCSVSNALG 7543
Score = 40.4 bits (93), Expect = 0.011
Identities = 22/83 (26%), Positives = 39/83 (46%), Gaps = 1/83 (1%)
Query: 12 FSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREV 71
F++ R+ E G+ A+ E + V W++G ++ ++Y L EGTR L + +
Sbjct: 3452 FTEGLRNEEAVEGATAMLWCELSKVA-PVEWRKGPENLRDGDRYILRQEGTRCELQICGL 3510
Query: 72 GPADQGSYAVIAGSSKVKFDLKV 94
AD G Y + G + L +
Sbjct: 3511 AMADAGEYLCVCGQERTSATLTI 3533
Score = 40.4 bits (93), Expect = 0.011
Identities = 21/73 (28%), Positives = 32/73 (43%)
Query: 7 KPVSAFSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTL 66
KPV P S +VAAG E E +V W +G I ++ + ++G + L
Sbjct: 4621 KPVPPQPSAPESRQVAAGEDVSLELEVVAEAGEVIWHKGMERIQPGGRFEVVSQGRQQML 4680
Query: 67 TVREVGPADQGSY 79
++ DQG Y
Sbjct: 4681 VIKGFTAEDQGEY 4693
Score = 40.0 bits (92), Expect = 0.014
Identities = 22/85 (25%), Positives = 38/85 (44%), Gaps = 1/85 (1%)
Query: 10 SAFSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVR 69
S F + R+ E G A E +A V W++G + +++ L +G+R L +R
Sbjct: 3714 SKFIEGLRNEEATEGDTATLWCELSKAA-PVEWRKGHETLRDGDRHSLRQDGSRCELQIR 3772
Query: 70 EVGPADQGSYAVIAGSSKVKFDLKV 94
+ D G Y+ + G + L V
Sbjct: 3773 GLAVVDAGEYSCVCGQERTSATLTV 3797
Score = 39.7 bits (91), Expect = 0.019
Identities = 26/73 (35%), Positives = 36/73 (49%), Gaps = 5/73 (6%)
Query: 982 TIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLA---GEEVSIRNSPTDTILFIRAARRV 1038
+I+ + G G PRP V+W+K+G+ L G V + + L IRAAR
Sbjct: 118 SIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPR 177
Query: 1039 HSGTYQVTVRIEN 1051
GTY+ VR EN
Sbjct: 178 DGGTYE--VRAEN 188
Score = 39.3 bits (90), Expect = 0.024
Identities = 26/79 (32%), Positives = 36/79 (45%), Gaps = 13/79 (16%)
Query: 435 QCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEV-SEEGAQVKWLKDGVEL 493
Q G K E+ +E P + + D VG + EC V S+ + +WLKDGVEL
Sbjct: 4880 QAAFKGYKVRKEMKQQEGP-MFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVEL 4938
Query: 494 TREETFKYRFKKDGQRHHL 512
T DG+ HH+
Sbjct: 4939 T-----------DGRHHHI 4946
Score = 38.5 bits (88), Expect = 0.041
Identities = 41/181 (22%), Positives = 65/181 (35%), Gaps = 21/181 (11%)
Query: 452 PPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKKDGQRHH 511
P + + PL+ + G V F +++ A +W DG L Y D RH
Sbjct: 611 PKLAVRTPLKAVQAVEGGEVTFSVDLTVASAG-EWFLDGQALKASSV--YEIHCDRTRHT 667
Query: 512 LIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQS------------IADLMVGAK 559
L I E G + G I ++EV + +++
Sbjct: 668 LTIREVPASLHGAQLKFVANG------IESSIRMEVRAAPGLTANKPPAAAAREVLARLH 721
Query: 560 DQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPE 619
++A E+SD+ WLK+G+ L P + +V L + DV D Y V
Sbjct: 722 EEAQLLAELSDQAAAVTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYECVSR 781
Query: 620 G 620
G
Sbjct: 782 G 782
Score = 38.5 bits (88), Expect = 0.041
Identities = 31/116 (26%), Positives = 47/116 (40%), Gaps = 2/116 (1%)
Query: 17 RSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQ 76
++V+ G F + A W G + AS+ Y + + TRHTLT+REV +
Sbjct: 620 KAVQAVEGGEVTFSVDLTVASAG-EWFLDGQALKASSVYEIHCDRTRHTLTIREVPASLH 678
Query: 77 GS-YAVIAGSSKVKFDLKVIEAEKAEPMLAPAPAPAEATGAPGEAPAPAAELGESA 131
G+ +A + ++V A PA A E E AEL + A
Sbjct: 679 GAQLKFVANGIESSIRMEVRAAPGLTANKPPAAAAREVLARLHEEAQLLAELSDQA 734
Score = 37.7 bits (86), Expect = 0.071
Identities = 31/104 (29%), Positives = 48/104 (46%), Gaps = 9/104 (8%)
Query: 1175 LDFSEAPSF--TQPLVNRSVIA--GYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMF 1230
LD SE + + L +R V A G A L C V + +++W+K+G L ++ RM
Sbjct: 1341 LDVSEPKAVFAKEQLAHRKVQAEAGAIATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRME 1399
Query: 1231 SKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVRVPQ 1274
+ L +++ C D G Y C A G R L+V P+
Sbjct: 1400 AVGCTRRLVVQQACQADTGEYSCEA----GGQRLSFSLDVAEPK 1439
Score = 37.0 bits (84), Expect = 0.12
Identities = 28/92 (30%), Positives = 38/92 (41%), Gaps = 6/92 (6%)
Query: 17 RSVEVAAGSPAVFEAETERAGVKV-RWQRGGSDISASNKYGLATEGTRHTLTVREVGPAD 75
+ V V +PA FE ET V+ +W G + + A GL EGT H L +R
Sbjct: 2386 QDVTVMEPAPAWFECETSIPSVRPPKWLLGKTVLQAGGNVGLEQEGTVHRLMLRRTCSTM 2445
Query: 76 QGSYAVIAGSSK-----VKFDLKVIEAEKAEP 102
G G S+ V D+ V+ EP
Sbjct: 2446 TGPVHFTVGKSRSSARLVVSDIPVVLTRPLEP 2477
Score = 37.0 bits (84), Expect = 0.12
Identities = 28/92 (30%), Positives = 40/92 (43%), Gaps = 5/92 (5%)
Query: 1183 FTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRK 1242
F + L ++ V G TA LCC + + + W K L L A+++M L +R
Sbjct: 3981 FLRELQHQEVDEGGTAHLCCELSRAGA-SVEWRKGSLQLFPCAKYQMVQDGAAAELLVRG 4039
Query: 1243 PCPFDGGIYVCRATNLQGEARCECRLEVRVPQ 1274
D G Y C + Q A L VRVP+
Sbjct: 4040 VEQEDAGDYTCDTGHTQSMA----SLSVRVPR 4067
Score = 36.2 bits (82), Expect = 0.21
Identities = 23/81 (28%), Positives = 39/81 (48%), Gaps = 5/81 (6%)
Query: 1194 AGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVC 1253
AG +A L C V + +++W+K+G L ++ RM + L +++ D G Y C
Sbjct: 1548 AGTSATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQEAGQADAGEYSC 1606
Query: 1254 RATNLQGEARCECRLEVRVPQ 1274
+A G+ R L V P+
Sbjct: 1607 KA----GDQRLSFHLHVAEPK 1623
Score = 36.2 bits (82), Expect = 0.21
Identities = 21/83 (25%), Positives = 36/83 (43%), Gaps = 1/83 (1%)
Query: 12 FSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREV 71
F++ R+ E G+ AV E + V W +G + +++ L +G R L +R +
Sbjct: 3628 FTEGLRNEEATEGATAVLRCELSKMA-PVEWWKGHETLRDGDRHSLRQDGARCELQIRGL 3686
Query: 72 GPADQGSYAVIAGSSKVKFDLKV 94
D G Y + G + L V
Sbjct: 3687 VAEDAGEYLCMCGKERTSAMLTV 3709
Score = 35.0 bits (79), Expect = 0.46
Identities = 18/57 (31%), Positives = 28/57 (49%)
Query: 40 VRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYAVIAGSSKVKFDLKVIE 96
V W + G +I S ++ A++G HTLTV D Y+ G+ F ++V E
Sbjct: 1750 VTWLKDGVEIRRSKRHETASQGDTHTLTVHGAQVLDSAIYSCRVGAEGQDFPVQVEE 1806
Score = 34.7 bits (78), Expect = 0.60
Identities = 22/81 (27%), Positives = 39/81 (48%), Gaps = 5/81 (6%)
Query: 1194 AGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVC 1253
AG +A L C V + +++W+K+G L ++ R+ + + L +++ D G Y C
Sbjct: 1272 AGASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEYTC 1330
Query: 1254 RATNLQGEARCECRLEVRVPQ 1274
A G R L+V P+
Sbjct: 1331 EA----GGQRLSFHLDVSEPK 1347
Score = 34.7 bits (78), Expect = 0.60
Identities = 17/37 (45%), Positives = 22/37 (59%), Gaps = 1/37 (2%)
Query: 458 RPLEDQLVMVGQRVEFECEVS-EEGAQVKWLKDGVEL 493
R L D+ V++GQ V C+VS + AQ W KDG L
Sbjct: 7467 RELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPL 7503
Score = 33.9 bits (76), Expect = 1.0
Identities = 43/154 (27%), Positives = 61/154 (39%), Gaps = 28/154 (18%)
Query: 3 EPGKKPVSAFSKK---PRSVE------VAAGSPAVFEAETERAGVK-VRWQRGGSDISA- 51
EP +KP S ++ PR +E V GS F + E V V W R ++
Sbjct: 5355 EPEEKPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVL 5414
Query: 52 -----SNKYGLATEGTRHTLTVREVGPADQGSYAVIA----------GSSKVKFDLKVIE 96
+ Y +A+ +H+L + +VG QG+Y IA S V KV E
Sbjct: 5415 WIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHVSGLPKVEE 5474
Query: 97 AEKAEPMLAPA--PAPAEATGAPGEAPAPAAELG 128
EK + L +A A G A A+LG
Sbjct: 5475 QEKVKEALISTFLQGTTQAISAQGLETASFADLG 5508
Score = 33.5 bits (75), Expect = 1.3
Identities = 19/61 (31%), Positives = 24/61 (39%)
Query: 17 RSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQ 76
++VE A E + A V W R G LA G HTLT+ + P D
Sbjct: 2084 QAVEAREQGTATMEVQLSHADVDGSWTRDGLRFQQGPTCHLAVRGPMHTLTLSGLRPEDS 2143
Query: 77 G 77
G
Sbjct: 2144 G 2144
Score = 33.1 bits (74), Expect = 1.7
Identities = 22/81 (27%), Positives = 38/81 (46%), Gaps = 5/81 (6%)
Query: 1194 AGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVC 1253
AG +A L C V + +++W+K+G L ++ M + L +++ D G Y C
Sbjct: 904 AGASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEYSC 962
Query: 1254 RATNLQGEARCECRLEVRVPQ 1274
A G R L+V+ P+
Sbjct: 963 EA----GGQRLSFHLDVKEPK 979
Score = 33.1 bits (74), Expect = 1.7
Identities = 23/81 (28%), Positives = 36/81 (44%), Gaps = 5/81 (6%)
Query: 1194 AGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVC 1253
AG +AML C V + +++W+K+G L ++ M K L + + D G Y C
Sbjct: 1088 AGASAMLSCEV-AQAQTEVTWYKDGKKLSSSSKVGMEVKGCTRRLVLPQAGKADAGEYSC 1146
Query: 1254 RATNLQGEARCECRLEVRVPQ 1274
A G R L + P+
Sbjct: 1147 EA----GGQRVSFHLHITEPK 1163
Score = 32.3 bits (72), Expect = 3.0
Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 5/77 (6%)
Query: 1194 AGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVC 1253
AG +A L C V + +++W+K+G L ++ R+ + L +++ D G Y C
Sbjct: 1640 AGASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRVEAVGCTRRLVVQQAGQADAGEYSC 1698
Query: 1254 RATNLQGEARCECRLEV 1270
A G R RL V
Sbjct: 1699 EA----GGQRLSFRLHV 1711
Score = 32.3 bits (72), Expect = 3.0
Identities = 25/89 (28%), Positives = 39/89 (43%), Gaps = 6/89 (6%)
Query: 1183 FTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRK 1242
FT+ L N + G TAML C + S + W K +L + R+ + + L+I
Sbjct: 3452 FTEGLRNEEAVEGATAMLWCEL--SKVAPVEWRKGPENLRDGDRYILRQEGTRCELQICG 3509
Query: 1243 PCPFDGGIYVCRATNLQGEARCECRLEVR 1271
D G Y+C + G+ R L +R
Sbjct: 3510 LAMADAGEYLC----VCGQERTSATLTIR 3534
Score = 32.3 bits (72), Expect = 3.0
Identities = 19/60 (31%), Positives = 27/60 (45%), Gaps = 3/60 (5%)
Query: 988 GEPVNLLIPFQGKPRPQVTWTKEGQPL-AGEEVSIRNSPTD--TILFIRAARRVHSGTYQ 1044
GE +G P PQ+ W K+G L G + + P +L IRAA + G Y+
Sbjct: 6122 GEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYE 6181
Score = 32.0 bits (71), Expect = 3.9
Identities = 21/80 (26%), Positives = 36/80 (45%), Gaps = 8/80 (10%)
Query: 27 AVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYAVIAGSS 86
A F E +V W G + + + ++ +G RHTL ++ + AD G ++ SS
Sbjct: 2575 ASFSCELSHEDEEVEWSLNGMPLYNDSFHEISHKGRRHTLVLKSIQRADAG---IVRASS 2631
Query: 87 KVKFDLKVIEAEKAEPMLAP 106
LKV + + E + P
Sbjct: 2632 -----LKVSTSARLEVRVKP 2646
Score = 32.0 bits (71), Expect = 3.9
Identities = 23/91 (25%), Positives = 35/91 (38%), Gaps = 3/91 (3%)
Query: 1173 KALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSK 1232
K + E P F+ + G L C V + W K+G++L D R +
Sbjct: 4890 KEMKQQEGPMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVEL-TDGRHHHIDQ 4948
Query: 1233 --QGVLTLEIRKPCPFDGGIYVCRATNLQGE 1261
G +L I D G Y C+ +N G+
Sbjct: 4949 LGDGTCSLLITGLDRADAGCYTCQVSNKFGQ 4979
Score = 32.0 bits (71), Expect = 3.9
Identities = 20/66 (30%), Positives = 28/66 (42%), Gaps = 1/66 (1%)
Query: 19 VEVAAGSPAVFEAETER-AGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQG 77
V+ G A FEA E V W + + S + EGT ++L +R V D G
Sbjct: 6366 VQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLVLRHVASKDAG 6425
Query: 78 SYAVIA 83
Y +A
Sbjct: 6426 VYTCLA 6431
Score = 31.6 bits (70), Expect = 5.1
Identities = 23/82 (28%), Positives = 38/82 (46%), Gaps = 3/82 (3%)
Query: 1182 SFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIR 1241
SF++PL + L C + P + W K+G++L + ++ +L I
Sbjct: 2167 SFSRPLQDVVTTEKEKVTLECEL-SRPNVDVRWLKDGVELRAGKTMAIAAQGACRSLTIY 2225
Query: 1242 KPCPF-DGGIYVCRATNLQGEA 1262
+ C F D G+YVC A + Q A
Sbjct: 2226 R-CEFADQGVYVCDAHDAQSSA 2246
Score = 31.6 bits (70), Expect = 5.1
Identities = 54/238 (22%), Positives = 80/238 (33%), Gaps = 36/238 (15%)
Query: 12 FSKKPRSVEVAAGSPAVFEAE-TERAGVKVRWQRGGSDISASNKYGLATEGTR-HTLTVR 69
F + ++ EV G P F+ T + VRW + G + + Y + + H L +
Sbjct: 5128 FLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQLIIT 5187
Query: 70 EVGPADQGSYAVIA----GSSKVKFDLKVIEAEKAEPMLAPAPAPAEATGAPGEAPAPAA 125
V PAD G Y +A G S K +L+V + T + A A
Sbjct: 5188 AVVPADMGVYRCLAENSMGVSSTKAELRV-----------------DLTSTDYDTAADAT 5230
Query: 126 ELGESAPSPKGSSSAALNGPTPGAPDDPIGLFVMRPQDGEVTVGGSIT-FSARVAGASLL 184
E + SS G + + V +D +V G + F +V G
Sbjct: 5231 ESSSYFSAQGYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKG---Y 5287
Query: 185 KPPVVKWFKGKWVDLSSKVGQHLQLHDSYDRASKVYLFELHITDAQPAFTGSYRCEVS 242
P + WFK GQ L K L L I +G Y +S
Sbjct: 5288 PAPRLYWFKD---------GQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYIS 5336
Score = 31.2 bits (69), Expect = 6.6
Identities = 20/78 (25%), Positives = 34/78 (43%), Gaps = 5/78 (6%)
Query: 1178 SEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPK-ISWFKNGLDLGEDARFRMFSKQGVL 1236
SE P +PLV + + ++ A +P ++W K+G+++ R S+
Sbjct: 1719 SERPCRREPLV----VKEHEDIILTATLATPSAATVTWLKDGVEIRRSKRHETASQGDTH 1774
Query: 1237 TLEIRKPCPFDGGIYVCR 1254
TL + D IY CR
Sbjct: 1775 TLTVHGAQVLDSAIYSCR 1792
Score = 30.8 bits (68), Expect = 8.6
Identities = 24/95 (25%), Positives = 37/95 (38%), Gaps = 5/95 (5%)
Query: 1181 PSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKI-SWFKNGLDLGEDARFRMFSKQGVLTLE 1239
P F L + G A LCC + + + W K G++L ++ M S+ L
Sbjct: 4068 PKFKTRLQSLEQETGDIARLCCQLSDAESGAVVQWLKEGVELHAGPKYEMRSQGATRELL 4127
Query: 1240 IRKPCPFDGGIYVCRATNLQGEARCECRLEVRVPQ 1274
I + D G Y C + G + L V P+
Sbjct: 4128 IHQLEAKDTGEYAC----VTGGQKTAASLRVTEPE 4158
Score = 30.8 bits (68), Expect = 8.6
Identities = 40/156 (25%), Positives = 61/156 (39%), Gaps = 20/156 (12%)
Query: 12 FSKKPRSVEVAAGSPAVFEAETERAGV-KVRWQRGGSDISASNKYGLATEGTRH--TLTV 68
F K R+ G A F E A ++RW + G+ ++ NK+ +E L +
Sbjct: 6110 FVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVI 6169
Query: 69 REVGPADQGSYAV----IAGSSKVKFDLKV----IEAEKA--EPMLAPAPAPAEATGAPG 118
R D G Y GS++ +L++ ++A++ L A A
Sbjct: 6170 RAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAVEDTTLERADQ 6229
Query: 119 EAPAPAAE-LGESAPSPKGSSSAALNGPTP---GAP 150
E + LG AP P S+ L GP P GAP
Sbjct: 6230 EVTSVLKRLLGPKAPGP---STGDLTGPGPCPRGAP 6262
>gi|140560917 myomesin 1 isoform b [Homo sapiens]
Length = 1589
Score = 135 bits (341), Expect = 2e-31
Identities = 125/480 (26%), Positives = 190/480 (39%), Gaps = 67/480 (13%)
Query: 732 DRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVID----VPDAPAAP---KISNVG 784
+R+ T KEDEG+YT+ V+ +Q + V V D + APAAP K
Sbjct: 463 ERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEAN 522
Query: 785 EDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEM 844
+D + W+ PA DGG PILGY +++ + + W + N ++ +IEG Y
Sbjct: 523 KDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIF 582
Query: 845 RVYAVNAIGMSRPSPASQPFMPIGP------------------------------PSEPT 874
RV AVN +G+ PS S+P + P P PT
Sbjct: 583 RVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPT 642
Query: 875 HLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGL-TEHTSILVKD 933
L+V + + + V L W+PP + G G+ Y VE C G W L + + D
Sbjct: 643 DLSVTEATRSYVVLSWKPPGQRGHEGI-MYFVEKCEAGTENWQRVNTELPVKSPRFALFD 701
Query: 934 LPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQ---LPRHLRQT-------- 982
L G FRVR N AG G P TE V + L P+ +P T
Sbjct: 702 LAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEE 761
Query: 983 ---IQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVH 1039
++ VG + + GK P P+ G + T R
Sbjct: 762 SKDAKELVGYYIEASVAGSGKWEP-----CNNNPVKGSRFTCHGLVTGQSYIFRVRAVNA 816
Query: 1040 SGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWG 1099
+G + + E +E KA + PSPP D+ +++ ++ L WK P +G E+ G
Sbjct: 817 AGLSEYSQDSEAIEVKAAIA-----PPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITG 871
Query: 1100 YTV---QKADKKTMEWFTV-LEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTK 1155
Y V + D +W ++ + L Y F+V + NM G +A ++
Sbjct: 872 YYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSE 931
Score = 92.8 bits (229), Expect = 2e-18
Identities = 116/517 (22%), Positives = 194/517 (37%), Gaps = 55/517 (10%)
Query: 771 VPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDL-IQEL 829
VP P ++ + W+PP G + I+ Y +E+ + + W R+N +L ++
Sbjct: 637 VPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSP 695
Query: 830 SHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PIGPPSEPTHLAVEDVSDTTV 886
+ EG Y RV N+ G+ PS A++ + + P P + +DT+V
Sbjct: 696 RFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSV 755
Query: 887 SLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRA 946
+ W E A L GY +E G +W + + L TG +FRVRA
Sbjct: 756 VVSWE--ESKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRA 813
Query: 947 HNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKV----------------GEP 990
N AG +E + V+ + P ++ + + G
Sbjct: 814 VNAAGLSEYSQDSEAIEVKAAIAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYY 873
Query: 991 VNLLIPFQGKPRPQVTWTKEGQPLAGEEV-SIRNSPTDTILFIRAARRVHSGTYQVTVRI 1049
VN G P W + EE I N + + + A +G +
Sbjct: 874 VNYREVIDGVPGK---WREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVS 930
Query: 1050 ENME-DKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTV--QKAD 1106
E + ++ T+ + P PP L+ ++ ++ L+WKPP G T + GY V ++A
Sbjct: 931 ECFKCEEWTIAV-----PGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAK 985
Query: 1107 KKTMEWFTVLE-HYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGI 1165
K +W + E + + V L G Y FRV + N G + V RPG
Sbjct: 986 AKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPG- 1044
Query: 1166 TYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDA 1225
T+ +V G ++ + +PK + SW K+ + +
Sbjct: 1045 ------------------TKEVVVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSP 1086
Query: 1226 RFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEA 1262
R + SK + + D GIY C T+ G A
Sbjct: 1087 RLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIA 1123
Score = 87.0 bits (214), Expect = 1e-16
Identities = 65/247 (26%), Positives = 102/247 (41%), Gaps = 15/247 (6%)
Query: 734 SIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPK------ISNVGEDS 787
S FT G ++ V N G + + + I+V A A P DS
Sbjct: 794 SRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIAPPSPPCDITCLESFRDS 853
Query: 788 CTVQWEPPAYDGGQPILGYILERKKKKSY---RWMRLNFDLIQELSHEARRMIEGVVYEM 844
+ W+ P GG I GY + ++ +W N + E +++ + E +VY+
Sbjct: 854 MVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQF 913
Query: 845 RVYAVNAIGMSRPSPASQPF----MPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGG 900
+V A+N G+ PS S+ F I P P L +V ++ L+W+PP G
Sbjct: 914 QVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTP 973
Query: 901 LDGYSVEYCPEGCSE--WVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTT 958
+ GY V+ E W + ++ + V+ L G +FRVRA N AG G P
Sbjct: 974 VTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDL 1033
Query: 959 TEPVTVQ 965
PV +
Sbjct: 1034 AGPVVAE 1040
Score = 79.3 bits (194), Expect = 2e-14
Identities = 130/649 (20%), Positives = 229/649 (35%), Gaps = 89/649 (13%)
Query: 391 DAEVKWLKNGQEIQMSGS--KYIFESIGAKRTLTISQCSLADDAAYQC----VVGGEKCS 444
+ V W KN I + + KYI ES TL I+ C D A Y+ V G
Sbjct: 305 EPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRASAMNVKGELSAY 364
Query: 445 TELFVKE----------PPVLITRPL---------------------------EDQLVMV 467
+ VK T PL E + + +
Sbjct: 365 ASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIHFDDKFDVSFGREGETMSL 424
Query: 468 GQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYAL 527
G RV E+ +++W ++GV L+ + + + G+R L + ED G Y +
Sbjct: 425 GCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWS--GERATLTFSHLNKEDEGLYTI 482
Query: 528 CTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPD 587
G+ ++ V+ AD + A + + N + + + V
Sbjct: 483 RVRMGE-----YYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDG 537
Query: 588 SRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKI 647
+ + ++ D + ++ F + + + V+ K+
Sbjct: 538 GSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRA-------VNKM 590
Query: 648 HLDCPGRIPDTIVVV-----AGNKLRLDVPISG-------DPAPTVI----WQKAITQGN 691
+ P R+ + + + A K R P +G +P+ ++ ++T+
Sbjct: 591 GIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEAT 650
Query: 692 KAPARPAPDAPEDTGDSDEWVFDKKLLCETEG--RVRVETTKDRSIFTVEGAEKEDEGVY 749
++ + P G F +K TE RV E F + + +
Sbjct: 651 RSYVVLSWKPPGQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCF 710
Query: 750 TVTVKNPVGEDQVNLTVKV------IDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPI 803
V N G + + +V +D+P AP S + S V WE + +
Sbjct: 711 RVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEESK--DAKEL 768
Query: 804 LGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQP 863
+GY +E S +W N + ++ ++ G Y RV AVNA G+S S S+
Sbjct: 769 VGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEA 828
Query: 864 F---MPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCP--EGC-SEWV 917
I PPS P + + ++ L W+ P+++G + GY V Y +G +W
Sbjct: 829 IEVKAAIAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWR 888
Query: 918 AALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQE 966
A + + +L F+V A NMAG GAP +E +E
Sbjct: 889 EANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEE 937
Score = 70.1 bits (170), Expect = 1e-11
Identities = 43/120 (35%), Positives = 62/120 (51%), Gaps = 4/120 (3%)
Query: 769 IDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERK--KKKSYRWMRLNFDLI 826
I VP P + K S V +DS +QW+PP + G P+ GY ++ K K K +W LN I
Sbjct: 940 IAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAI 999
Query: 827 QELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTV 886
+ + + R + EGV Y RV A+N G+ +PS + P + P T V +V D V
Sbjct: 1000 KNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPG--TKEVVVNVDDDGV 1057
Score = 57.8 bits (138), Expect = 7e-08
Identities = 77/336 (22%), Positives = 131/336 (38%), Gaps = 69/336 (20%)
Query: 471 VEFECEVS--EEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALC 528
V +C+V+ ++ + W KD E++ +E + KDG L+I E +DAG Y +
Sbjct: 1278 VLLKCKVANIKKETHIVWYKDEREISVDEKHDF---KDGICT-LLITEFSKKDAGIYEVI 1333
Query: 529 TSGGQA-------LAELIVQEKKLEVYQSIA----DLMVGAKDQAVFKCEVSD---ENVR 574
+ L + +E +EV + IA DL + + + + E+++
Sbjct: 1334 LKDDRGKDKSRLKLVDEAFKELMMEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVEDLK 1393
Query: 575 GVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGF--------ACNLS 626
W NG + R+K G L I++ TP D+ Y V E F +LS
Sbjct: 1394 VNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKY--VMELFDGKTGHQKTVDLS 1451
Query: 627 AKLH------FMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPT 680
+ + F +K + + ++ G +PD + + G L L + GDP P
Sbjct: 1452 GQAYDEAYAEFQRLKQAAIAEKNRARVL----GGLPDVVTIQEGKALNLTCNVWGDPPPE 1507
Query: 681 VIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEG 740
V W K +K L + ++ E + + FT+ G
Sbjct: 1508 VSWLKN---------------------------EKALASDDHCNLKFEAGRT-AYFTING 1539
Query: 741 AEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPA 776
D G Y + VKN G + + TV V +P+ A
Sbjct: 1540 VSTADSGKYGLVVKNKYGSETSDFTVSVF-IPEEEA 1574
Score = 40.4 bits (93), Expect = 0.011
Identities = 27/86 (31%), Positives = 45/86 (52%), Gaps = 5/86 (5%)
Query: 1180 APSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDA---RFRMFSKQGVL 1236
AP F + +V L C++ G P+P+++W+KN + + A ++ + S+ G+
Sbjct: 276 APEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMH 335
Query: 1237 TLEIRKPCPF-DGGIYVCRATNLQGE 1261
TLEI C F D Y A N++GE
Sbjct: 336 TLEI-NGCDFEDTAQYRASAMNVKGE 360
Score = 33.5 bits (75), Expect = 1.3
Identities = 22/78 (28%), Positives = 41/78 (52%), Gaps = 6/78 (7%)
Query: 358 DEKKSTAFQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFES-IG 416
D+K +F ++ E +S G ++ +T E+ E++W +NG + +S SK++ G
Sbjct: 408 DDKFDVSFGREGET---MSLGCRVVITPEIKHFQPEIQWYRNG--VPLSPSKWVQTLWSG 462
Query: 417 AKRTLTISQCSLADDAAY 434
+ TLT S + D+ Y
Sbjct: 463 ERATLTFSHLNKEDEGLY 480
Score = 32.0 bits (71), Expect = 3.9
Identities = 22/81 (27%), Positives = 29/81 (35%), Gaps = 1/81 (1%)
Query: 1195 GYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRM-FSKQGVLTLEIRKPCPFDGGIYVC 1253
G L C V G P P++SW KN L D + F I D G Y
Sbjct: 1491 GKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGL 1550
Query: 1254 RATNLQGEARCECRLEVRVPQ 1274
N G + + V +P+
Sbjct: 1551 VVKNKYGSETSDFTVSVFIPE 1571
Score = 31.6 bits (70), Expect = 5.1
Identities = 27/120 (22%), Positives = 44/120 (36%), Gaps = 24/120 (20%)
Query: 21 VAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYA 80
++ G V E + +++W R G +S S G R TLT + D+G Y
Sbjct: 422 MSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYT 481
Query: 81 V-----------------------IAGSSKVKFDLKVIEAEKAEPMLAPAPAPAEATGAP 117
+ I G+ D+K +EA K + ++ PA G+P
Sbjct: 482 IRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANK-DYIIISWKQPAVDGGSP 540
Score = 31.2 bits (69), Expect = 6.6
Identities = 25/90 (27%), Positives = 34/90 (37%), Gaps = 1/90 (1%)
Query: 350 KRLKGMRRDEKKSTAFQKKLEPAYQVSKGHKIRLTVEL-ADHDAEVKWLKNGQEIQMSGS 408
+RLK EK L + +G + LT + D EV WLKN + +
Sbjct: 1463 QRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDH 1522
Query: 409 KYIFESIGAKRTLTISQCSLADDAAYQCVV 438
+ G TI+ S AD Y VV
Sbjct: 1523 CNLKFEAGRTAYFTINGVSTADSGKYGLVV 1552
>gi|156104903 myomesin 2 [Homo sapiens]
Length = 1465
Score = 126 bits (317), Expect = 1e-28
Identities = 91/326 (27%), Positives = 142/326 (43%), Gaps = 24/326 (7%)
Query: 736 FTVEGAEKEDEGVYTVTVKNPVG------EDQVNLTVKVIDVPDAPAAPKISNVGEDSCT 789
F V G ++ ++ V N VG E V + VP P + N S T
Sbjct: 669 FVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMT 728
Query: 790 VQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAV 849
+ W+ P + GG PILGY L++++ W +N + + EG +YE ++ AV
Sbjct: 729 LGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAV 788
Query: 850 NAIGMSRPSPASQPFM----PIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYS 905
N G+ PS S+ F + P L +V DT++ + W+ P G+ + GY
Sbjct: 789 NLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYF 848
Query: 906 VEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQ 965
V++ E EW+ Q T + + V DL G +FRVRA N G G P T+EPV V+
Sbjct: 849 VDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVE 908
Query: 966 EILQRPRLQLPRHLRQTIQKKVGEPVNLLIPF---QGKPRPQVTWTKEGQPLAGEE-VSI 1021
R + I V E N+ + F + Q TW K + ++ +E I
Sbjct: 909 ----------ARPGTKEISAGVDEQGNIYLGFDCQEMTDASQFTWCKSYEEISDDERFKI 958
Query: 1022 RNSPTDTILFIRAARRVHSGTYQVTV 1047
+ L+++ + GTY V+V
Sbjct: 959 ETVGDHSKLYLKNPDKEDLGTYSVSV 984
Score = 109 bits (273), Expect = 1e-23
Identities = 127/553 (22%), Positives = 212/553 (38%), Gaps = 86/553 (15%)
Query: 710 EWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTV--KNPVGEDQVNLTVK 767
EW D LL E++ ++ + ++ + K+DEG+YT+ + + V + L V+
Sbjct: 315 EWYRDDVLLKESKW-TKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVR 373
Query: 768 VID--VPDAPAAP---KISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLN 822
D V AP AP + + D V W+PP P++GY ++R + + W++ N
Sbjct: 374 DADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCN 433
Query: 823 FDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGP------------- 869
++ + + EG Y RV AVN+ G+SRPS S + P
Sbjct: 434 DAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEG 493
Query: 870 -----------------PSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEG 912
P PT + ++S V L W PP G L Y +E G
Sbjct: 494 EKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPL-MYFIEKSVVG 552
Query: 913 CSEWVAA-LQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRP 971
W Q V DL G +FRV + N G P T P+ Q++ P
Sbjct: 553 SGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVP 612
Query: 972 ----RLQLPRHLRQTIQKKVGEP-----------------VNLLIPFQGKPRPQVTWTKE 1010
R+ R+ + ++ + P NL P KP +
Sbjct: 613 SAPGRVLASRNTKTSVVVQWDRPKHEEDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVH 672
Query: 1011 GQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQ-VVDKPSPP 1069
G GE+ R ++A V EN ++ + +Q + PS P
Sbjct: 673 GL-TTGEQYIFR---------VKAVNAVGMS--------ENSQESDVIKVQAALTVPSHP 714
Query: 1070 QDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTV-LEHYRRTHCVVPE 1128
+ + + G ++ L WK P+ G + + GY + K + W V + T V
Sbjct: 715 YGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDG 774
Query: 1129 LIIGNGYYFRVFSQNMVGFSDRAATTK----EPVFIPRPGITYEPPNYKALDFSEAPSFT 1184
L G+ Y F++ + N+ G + + ++ E +P PG Y+ + D S +
Sbjct: 775 LTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWK 834
Query: 1185 QPLVN-RSVIAGY 1196
P+ + S ++GY
Sbjct: 835 APVYSGSSPVSGY 847
Score = 95.1 bits (235), Expect = 4e-19
Identities = 119/525 (22%), Positives = 198/525 (37%), Gaps = 80/525 (15%)
Query: 771 VPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDL-IQEL 829
VP P S + + + WEPP G P++ Y +E+ S W R+N ++
Sbjct: 510 VPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSP 568
Query: 830 SHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGP---PSEPTHLAVEDVSDTTV 886
+ ++EG Y RV + N G+S PS + P PS P + + T+V
Sbjct: 569 RYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSV 628
Query: 887 SLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRA 946
++W P+ L GY V+ C G + W + +V L TG + +FRV+A
Sbjct: 629 VVQWDRPKH--EEDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKA 686
Query: 947 HNMAGPGAPVTTTEPVTVQEILQRPRLQLPRH-LRQTIQKKVGEPVNLLIPFQGKPRPQV 1005
N G ++ + VQ L +P H T+ G + L G P+
Sbjct: 687 VNAVGMSENSQESDVIKVQ-----AALTVPSHPYGITLLNCDGHSMTL-----GWKVPKF 736
Query: 1006 TWTKEGQPLAG-----EEV------SIRNSPT-DTILFIRAARRVHSGTYQVTVRIENM- 1052
+ G P+ G EV + +SP+ TIL + Y+ + N+
Sbjct: 737 S---GGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGL--TEGSLYEFKIAAVNLA 791
Query: 1053 --------EDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQK 1104
+ + +P P DL + ++ + WK P G++ + GY V
Sbjct: 792 GIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDF 851
Query: 1105 ADKKTMEWFTVLE-HYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFI-PR 1162
++ EW TV + + V +L G Y FRV + N G + + T EPV + R
Sbjct: 852 REEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVG-KPSDTSEPVLVEAR 910
Query: 1163 P-------GITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWF 1215
P G+ + Y D E +Q +W
Sbjct: 911 PGTKEISAGVDEQGNIYLGFDCQEMTDASQ--------------------------FTWC 944
Query: 1216 KNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQG 1260
K+ ++ +D RF++ + L ++ P D G Y ++ G
Sbjct: 945 KSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDG 989
Score = 50.4 bits (119), Expect = 1e-05
Identities = 38/136 (27%), Positives = 60/136 (44%), Gaps = 36/136 (26%)
Query: 653 GRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWV 712
G +PD + ++ G L L + G+P P VIW K
Sbjct: 1348 GGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKN-------------------------- 1381
Query: 713 FDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVI--- 769
D+ + V+VE K S+ T++G ED G Y++ +KN G +++++TV V
Sbjct: 1382 -DQDIQLSEHFSVKVEQAKYVSM-TIKGVTSEDSGKYSINIKNKYGGEKIDVTVSVYKHG 1439
Query: 770 -DVPD-AP---AAPKI 780
+PD AP A PK+
Sbjct: 1440 EKIPDMAPPQQAKPKL 1455
Score = 49.7 bits (117), Expect = 2e-05
Identities = 31/97 (31%), Positives = 44/97 (45%), Gaps = 3/97 (3%)
Query: 1178 SEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNG---LDLGEDARFRMFSKQG 1234
S AP L + +V + LC V+G P P + W+K+G E ++R+ S G
Sbjct: 151 SRAPEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYG 210
Query: 1235 VLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVR 1271
V TLEI + D Y ATN G+ + VR
Sbjct: 211 VHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVVR 247
Score = 38.9 bits (89), Expect = 0.032
Identities = 22/81 (27%), Positives = 38/81 (46%), Gaps = 1/81 (1%)
Query: 1191 SVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQG-VLTLEIRKPCPFDGG 1249
+++ G T L C V G+P P++ WFKN D+ F + +Q +++ I+ D G
Sbjct: 1355 TIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSG 1414
Query: 1250 IYVCRATNLQGEARCECRLEV 1270
Y N G + + + V
Sbjct: 1415 KYSINIKNKYGGEKIDVTVSV 1435
Score = 34.3 bits (77), Expect = 0.78
Identities = 31/146 (21%), Positives = 60/146 (41%), Gaps = 16/146 (10%)
Query: 473 FECEVSEEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGG 532
F+C+ + +Q W K E++ +E FK + G L + ED G Y++ S
Sbjct: 930 FDCQEMTDASQFTWCKSYEEISDDERFK--IETVGDHSKLYLKNPDKEDLGTYSVSVSDT 987
Query: 533 QALAELIV-----QEKKLEVYQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPD 587
++ V E+ + + I + + K + + E+ D+ WL+ + L PD
Sbjct: 988 DGVSSSFVLDPEELERLMALSNEIKNPTIPLKSELAY--EIFDKGRVRFWLQ-AEHLSPD 1044
Query: 588 SRIKVSHIGR------VHKLTIDDVT 607
+ + R +H++ D T
Sbjct: 1045 ASYRFIINDREVSDSEIHRIKCDKAT 1070
Score = 33.9 bits (76), Expect = 1.0
Identities = 39/156 (25%), Positives = 64/156 (41%), Gaps = 25/156 (16%)
Query: 317 AEEDVWEILRQAPPSEYERIAFQYGVTDLRGMLKR---LKGMRRDEK-------KSTAFQ 366
+EE W L+ P+E ++ + + + D + +R L G DE K+ AF
Sbjct: 1282 SEEMAW--LQICEPTEKDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFA 1339
Query: 367 KK--------LEPAYQVSKGHKIRLTVEL-ADHDAEVKWLKNGQEIQMSGSKYIFESIGA 417
+K L + +G + LT + + D EV W KN Q+IQ+S +
Sbjct: 1340 EKNRGRLIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAK 1399
Query: 418 KRTLTISQCSLADDAAYQCVV----GGEKCSTELFV 449
++TI + D Y + GGEK + V
Sbjct: 1400 YVSMTIKGVTSEDSGKYSINIKNKYGGEKIDVTVSV 1435
>gi|144226847 obscurin-like 1 [Homo sapiens]
Length = 1896
Score = 124 bits (312), Expect = 4e-28
Identities = 160/671 (23%), Positives = 246/671 (36%), Gaps = 105/671 (15%)
Query: 28 VFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYAVIAGSSK 87
V E R VRW + G ++ S L +G R L + P D G + AG
Sbjct: 1008 VLMCELSREDAPVRWYKDGLEVEESEALVLERDGPRCRLVLPAAQPEDGGEFVCDAGDDS 1067
Query: 88 VKFDLKVIEAEKAEPMLAPAPAPAEAT-GAPG--EAPAPAAELGESAPSPKGS----SSA 140
F + V E ++ PA + GAPG E A G K +S
Sbjct: 1068 AFFTVTV--TAPPERIVHPAARSLDLHFGAPGRVELRCEVAPAGSQVRWYKDGLEVEASD 1125
Query: 141 ALN----GPT-----PGAPDDPIGLFVMRPQDGEVTV----------------------- 168
AL GPT P A + G +V + +T
Sbjct: 1126 ALQLGAEGPTRTLTLPHAQPEDAGEYVCETRHEAITFNVILAEPPVQFLALETTPSPLCV 1185
Query: 169 --GGSITFSARVAGASLLKPPVVKWFKGKWVDLSSKVGQHLQLHDSYDRASKVYLFELHI 226
G + S ++ A PVV G+ V + G+ L+LH R L I
Sbjct: 1186 APGEPVVLSCELSRAGA---PVVWSHNGRPV----QEGEGLELHAEGPRRV------LCI 1232
Query: 227 TDAQPAFTGSYRCEVSTKDKFDCSNFNLTVHE----------------AMGTGDLDLLSA 270
A PA G Y C+ +F + V E + GDL+L+
Sbjct: 1233 QAAGPAHAGLYTCQSGAAPGAPSLSFTVQVAEPPVRVVAPEAAQTRVRSTPGGDLELV-- 1290
Query: 271 FRRTSLAGGGRRISDSHEDTGILDFSSLLKKRDSFRTPRDSKLEAPAEEDVWEILRQAPP 330
L+G G + + + + ++ R + +++ D E L AP
Sbjct: 1291 ---VHLSGPGGPVRWYKDGERLASQGRVQLEQAGAR--QVLRVQGARSGDAGEYLCDAPQ 1345
Query: 331 SEYERIAFQYGVTDLRGMLKRLKGMRRDEKKSTAFQKKLEPAYQVSKGHKIRLTVELADH 390
R+ + +E +L P V +G E++
Sbjct: 1346 DS------------------RIFLVSVEEPLLVKLVSELTPL-TVHEGDDATFRCEVSPP 1386
Query: 391 DAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCSTELFVK 450
DA+V WL+NG + G + G+ R LT+ C L D G S L V+
Sbjct: 1387 DADVTWLRNGAVVT-PGPQVEMAQNGSSRILTLRGCQLGDAGTVTLRAGSTATSARLHVR 1445
Query: 451 EPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQ--VKWLKDGVELTREETFKYRFKKDGQ 508
E +L R L+D GQ V E E GA V+W++ G L + + +DG
Sbjct: 1446 ETELLFLRRLQDVRAEEGQDVCLEVETGRVGAAGAVRWVRGGQPLPHDS--RLSMAQDGH 1503
Query: 509 RHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFKCEV 568
H L I+ +L D G Y + + LA L V+ ++L V + + D+ + A F+ E+
Sbjct: 1504 IHRLFIHGVILADQGTYGCESHHDRTLARLSVRPRQLRVLRPLEDVTISEGGSATFQLEL 1563
Query: 569 SDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAK 628
S E V G W + G +L P + + G H+L ++ + AD SF + C +A+
Sbjct: 1564 SQEGVTGEWARGGVQLYPGPKCHIHSDGHRHRLVLNGLGLADSGCVSFTADSLRC--AAR 1621
Query: 629 LHFMEVKIDFV 639
L EV + V
Sbjct: 1622 LIVREVPVTIV 1632
Score = 122 bits (307), Expect = 2e-27
Identities = 162/649 (24%), Positives = 247/649 (38%), Gaps = 86/649 (13%)
Query: 17 RSVEVAAGSPAVFE--AETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPA 74
RS+++ G+P E E AG +VRW + G ++ AS+ L EG TLT+ P
Sbjct: 1087 RSLDLHFGAPGRVELRCEVAPAGSQVRWYKDGLEVEASDALQLGAEGPTRTLTLPHAQPE 1146
Query: 75 DQGSYAVIAGSSKVKFDLKVIEAEKAEPMLA----PAP---APAEAT---------GAP- 117
D G Y + F+ VI AE LA P+P AP E GAP
Sbjct: 1147 DAGEYVCETRHEAITFN--VILAEPPVQFLALETTPSPLCVAPGEPVVLSCELSRAGAPV 1204
Query: 118 -----GEAPAPAAELGESAPSPK--------GSSSAAL----NGPTPGAPDDPIGLFVMR 160
G L A P+ G + A L +G PGAP + V
Sbjct: 1205 VWSHNGRPVQEGEGLELHAEGPRRVLCIQAAGPAHAGLYTCQSGAAPGAPSLSFTVQVAE 1264
Query: 161 PQDGEV-----------TVGGSITFSARVAGASLLKPPVVKWFK-GKWVDLSSKVGQHLQ 208
P V T GG + ++G V+W+K G+ + +V Q
Sbjct: 1265 PPVRVVAPEAAQTRVRSTPGGDLELVVHLSGPG----GPVRWYKDGERLASQGRV----Q 1316
Query: 209 LHDSYDRASKVYLFELHITDAQPAFTGSYRCEVSTKDKFDCSNFNLTVHEAMGTGDLDLL 268
L + R L + A+ G Y C+ + F ++V E + + L+
Sbjct: 1317 LEQAGARQV------LRVQGARSGDAGEYLCDAPQDSRI----FLVSVEEPLL---VKLV 1363
Query: 269 SAFRRTSLAGGGRRISDSHEDTGILDFSSLLKKRDSFRTPRDSKLEAPAEEDVWEILRQA 328
S ++ G D + L + + TP A LR
Sbjct: 1364 SELTPLTVHEGDDATFRCEVSPPDADVTWL--RNGAVVTPGPQVEMAQNGSSRILTLRGC 1421
Query: 329 PPSEYERIAFQYGVTDLRGMLKRLKGMRRDEKKSTAFQKKLEPAYQVSKGHKIRLTVELA 388
+ + + G T L +R E F ++L+ + +G + L VE
Sbjct: 1422 QLGDAGTVTLRAGSTATSARLH----VRETE---LLFLRRLQDV-RAEEGQDVCLEVETG 1473
Query: 389 DHDAE--VKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCSTE 446
A V+W++ GQ + S+ G L I LAD Y C ++
Sbjct: 1474 RVGAAGAVRWVRGGQPLPHD-SRLSMAQDGHIHRLFIHGVILADQGTYGCESHHDRTLAR 1532
Query: 447 LFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKKD 506
L V+ + + RPLED + G F+ E+S+EG +W + GV+L K D
Sbjct: 1533 LSVRPRQLRVLRPLEDVTISEGGSATFQLELSQEGVTGEWARGGVQLYPGP--KCHIHSD 1590
Query: 507 GQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFKC 566
G RH L++N L D+G + + A LIV+E + + + DL V D A F+C
Sbjct: 1591 GHRHRLVLNGLGLADSGCVSFTADSLRCAARLIVREVPVTIVRGPHDLEVTEGDTATFEC 1650
Query: 567 EVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYS 615
E+S W K+G L P R+++ +G L + P+D YS
Sbjct: 1651 ELSQALADVTWEKDGNALTPSPRLRLQALGTRRLLQLRRCGPSDAGTYS 1699
Score = 107 bits (267), Expect = 7e-23
Identities = 212/928 (22%), Positives = 332/928 (35%), Gaps = 163/928 (17%)
Query: 380 KIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVG 439
++ LT EL AEV+W K+G+E+ S + + + R L + L D Y C +
Sbjct: 915 RVVLTCELCRPWAEVRWTKDGEEVVESPA-LLLQKEDTVRRLVLPAVQLEDSGEYLCEID 973
Query: 440 GEKCSTELFVKEPPVLITRPLEDQLVMVGQRVE---FECEVSEEGAQVKWLKDGVELTRE 496
E S + V EPPV I P D++ ++ +E CE+S E A V+W KDG+E+ E
Sbjct: 974 DESASFTVTVTEPPVRIIYP-RDEVTLIAVTLECVVLMCELSREDAPVRWYKDGLEV--E 1030
Query: 497 ETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIA---D 553
E+ ++DG R L++ A ED G + A + V + A D
Sbjct: 1031 ESEALVLERDGPRCRLVLPAAQPEDGGEFVCDAGDDSAFFTVTVTAPPERIVHPAARSLD 1090
Query: 554 LMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEAD 613
L GA + +CEV+ + W K+G E+ +++ G LT+ P D +
Sbjct: 1091 LHFGAPGRVELRCEVAPAGSQVRWYKDGLEVEASDALQLGAEGPTRTLTLPHAQPEDAGE 1150
Query: 614 YSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPI 673
Y A + L EPP + P + V G + L +
Sbjct: 1151 YVCETRHEAITFNVIL------------AEPP-VQFLALETTPSPLCVAPGEPVVLSCEL 1197
Query: 674 SGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDR 733
S AP V W + + + E EG + + R
Sbjct: 1198 SRAGAPVV-----------------------------WSHNGRPVQEGEG-LELHAEGPR 1227
Query: 734 SIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPKISNV-------GED 786
+ ++ A G+YT G ++ TV+V + P AP+ + G+
Sbjct: 1228 RVLCIQAAGPAHAGLYTCQSGAAPGAPSLSFTVQVAEPPVRVVAPEAAQTRVRSTPGGDL 1287
Query: 787 SCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVY---- 842
V P G P+ Y + R Q L + R + Y
Sbjct: 1288 ELVVHLSGP----GGPVRWYKDGERLASQGRVQLEQAGARQVLRVQGARSGDAGEYLCDA 1343
Query: 843 --EMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPE------ 894
+ R++ V+ +P + + SE T L V + D T + PP+
Sbjct: 1344 PQDSRIFLVS---------VEEPLL-VKLVSELTPLTVHEGDDATFRCEVSPPDADVTWL 1393
Query: 895 RVGAGGLDGYSVEYCPEGCSEWVAALQG--LTEHTSILVKDLPTGARLLFRVRAHNMAGP 952
R GA G VE G S + L+G L + ++ ++ T VR
Sbjct: 1394 RNGAVVTPGPQVEMAQNGSSR-ILTLRGCQLGDAGTVTLRAGSTATSARLHVRE------ 1446
Query: 953 GAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPF-QGKPRPQVTWTKEG 1011
E+L RL Q ++ + G+ V L + + V W + G
Sbjct: 1447 ------------TELLFLRRL-------QDVRAEEGQDVCLEVETGRVGAAGAVRWVRGG 1487
Query: 1012 QPLAGE-EVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQ 1070
QPL + +S+ LFI GTY E+ D+ L V P+
Sbjct: 1488 QPLPHDSRLSMAQDGHIHRLFIHGVILADQGTY----GCESHHDRTLARLSV-----RPR 1538
Query: 1071 DLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQ---KADKKTMEWFT-VLEHYRRTHCVV 1126
LRV +P +DV +E T Q + T EW ++ Y C
Sbjct: 1539 QLRVL-----------RPLEDVTISEGGSATFQLELSQEGVTGEWARGGVQLYPGPKC-- 1585
Query: 1127 PELIIGNGYYFRVFSQNMVGFSDRAAT--TKEPVFIPRPGITYEPPNYKALDFSEAPSFT 1184
I +G+ R+ N +G +D T + + I E P + P
Sbjct: 1586 --HIHSDGHRHRLV-LNGLGLADSGCVSFTADSLRCAARLIVREVP----VTIVRGPH-- 1636
Query: 1185 QPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPC 1244
+ V G TA C + ++W K+G L R R+ + L++R+
Sbjct: 1637 ----DLEVTEGDTATFECEL-SQALADVTWEKDGNALTPSPRLRLQALGTRRLLQLRRCG 1691
Query: 1245 PFDGGIYVCRATNLQGEARC-ECRLEVR 1271
P D G Y C G AR RL VR
Sbjct: 1692 PSDAGTYSCAV----GTARAGPVRLTVR 1715
Score = 103 bits (256), Expect = 1e-21
Identities = 68/243 (27%), Positives = 106/243 (43%), Gaps = 4/243 (1%)
Query: 375 VSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAY 434
+S+G +EL+ +W + G ++ G K S G + L ++ LAD
Sbjct: 1551 ISEGGSATFQLELSQEGVTGEWARGGVQLY-PGPKCHIHSDGHRHRLVLNGLGLADSGCV 1609
Query: 435 QCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELT 494
+C+ L V+E PV I R D V G FECE+S+ A V W KDG LT
Sbjct: 1610 SFTADSLRCAARLIVREVPVTIVRGPHDLEVTEGDTATFECELSQALADVTWEKDGNALT 1669
Query: 495 REETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQA-LAELIVQEKKLEVYQSIAD 553
+ R + G R L + DAG Y+ +A L V+E+ + V +
Sbjct: 1670 PSP--RLRLQALGTRRLLQLRRCGPSDAGTYSCAVGTARAGPVRLTVRERTVAVLSELRS 1727
Query: 554 LMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEAD 613
+ D A F+C VS+ G W G+ L P +R+++ G+ H L + ++ D +
Sbjct: 1728 VSAREGDGATFECTVSEVETTGRWELGGRPLRPGARVRIRQEGKKHILVLSELRAEDAGE 1787
Query: 614 YSF 616
F
Sbjct: 1788 VRF 1790
Score = 99.4 bits (246), Expect = 2e-20
Identities = 70/245 (28%), Positives = 112/245 (45%), Gaps = 9/245 (3%)
Query: 374 QVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAA 433
+V++G EL+ A+V W K+G + S + +++G +R L + +C +D
Sbjct: 1639 EVTEGDTATFECELSQALADVTWEKDGNALTPS-PRLRLQALGTRRLLQLRRCGPSDAGT 1697
Query: 434 YQCVVGGEKCS-TELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVE 492
Y C VG + L V+E V + L G FEC VSE +W G
Sbjct: 1698 YSCAVGTARAGPVRLTVRERTVAVLSELRSVSAREGDGATFECTVSEVETTGRWELGGRP 1757
Query: 493 LTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIA 552
L + R +++G++H L+++E EDAG Q+LA L V+ L++ +
Sbjct: 1758 L--RPGARVRIRQEGKKHILVLSELRAEDAGEVRFQAGPAQSLALLEVEALPLQMCRHPP 1815
Query: 553 ---DLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPA 609
++VG + AV + VS WL+ G EL P + ++ G H L I DV P
Sbjct: 1816 REKTVLVGRR--AVLEVTVSRSGGHVCWLREGAELCPGDKYEMRSHGPTHSLVIHDVRPE 1873
Query: 610 DEADY 614
D+ Y
Sbjct: 1874 DQGTY 1878
Score = 89.4 bits (220), Expect = 2e-17
Identities = 77/276 (27%), Positives = 119/276 (43%), Gaps = 15/276 (5%)
Query: 375 VSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAY 434
V+ G + L+ EL+ A V W NG+ +Q G + G +R L I A Y
Sbjct: 1185 VAPGEPVVLSCELSRAGAPVVWSHNGRPVQ-EGEGLELHAEGPRRVLCIQAAGPAHAGLY 1243
Query: 435 QC----VVGGEKCSTELFVKEPPVLITRPLEDQLVM---VGQRVEFECEVSEEGAQVKWL 487
C G S + V EPPV + P Q + G +E +S G V+W
Sbjct: 1244 TCQSGAAPGAPSLSFTVQVAEPPVRVVAPEAAQTRVRSTPGGDLELVVHLSGPGGPVRWY 1303
Query: 488 KDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKL-- 545
KDG L + + + ++ G R L + A DAG Y LC + + L+ E+ L
Sbjct: 1304 KDGERLASQG--RVQLEQAGARQVLRVQGARSGDAGEY-LCDAPQDSRIFLVSVEEPLLV 1360
Query: 546 EVYQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDD 605
++ + L V D A F+CEVS + WL+NG + P +++++ G LT+
Sbjct: 1361 KLVSELTPLTVHEGDDATFRCEVSPPDADVTWLRNGAVVTPGPQVEMAQNGSSRILTLRG 1420
Query: 606 VTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPR 641
D + A SA+LH E ++ F+ R
Sbjct: 1421 CQLGDAGTVTLRAGSTA--TSARLHVRETELLFLRR 1454
Score = 84.7 bits (208), Expect = 5e-16
Identities = 86/349 (24%), Positives = 137/349 (39%), Gaps = 45/349 (12%)
Query: 381 IRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGG 440
+ L E+ DA V+W K+GQE++ S + E+ G R L + +D +QCV G
Sbjct: 825 VMLACEVDREDAPVRWYKDGQEVEESDF-VVLENEGPHRRLVLPATQPSDGGEFQCVAGD 883
Query: 441 EKCSTELFVKEPPVLITRPLEDQLVMVG--QRVEFECEVSEEGAQVKWLKDGVELTREET 498
E + + + I P V +RV CE+ A+V+W KDG E+ E+
Sbjct: 884 ECAYFTVTITDVSSWIVYPSGKVYVAAVRLERVVLTCELCRPWAEVRWTKDGEEVV--ES 941
Query: 499 FKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVY--QSIADLMV 556
+K+ L++ LED+G Y A + V E + + + L+
Sbjct: 942 PALLLQKEDTVRRLVLPAVQLEDSGEYLCEIDDESASFTVTVTEPPVRIIYPRDEVTLIA 1001
Query: 557 GAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSF 616
+ V CE+S E+ W K+G E+ + + G +L + P D +
Sbjct: 1002 VTLECVVLMCELSREDAPVRWYKDGLEVEESEALVLERDGPRCRLVLPAAQPEDGGE--- 1058
Query: 617 VPEGFACNLSAKLHFMEVKIDFVPRQ------EPPKIHLDCPGRIPDTIVVVAGNKLRLD 670
F C+ F V + P + +H PGR+ +LR +
Sbjct: 1059 ----FVCDAGDDSAFFTVTVTAPPERIVHPAARSLDLHFGAPGRV----------ELRCE 1104
Query: 671 VPISGDPAPTVIWQK---------AITQGNKAPAR--PAPDA-PEDTGD 707
V +G V W K A+ G + P R P A PED G+
Sbjct: 1105 VAPAGS---QVRWYKDGLEVEASDALQLGAEGPTRTLTLPHAQPEDAGE 1150
Score = 80.5 bits (197), Expect = 1e-14
Identities = 61/240 (25%), Positives = 103/240 (42%), Gaps = 9/240 (3%)
Query: 380 KIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVG 439
++ LT EL+ D W K+GQ+++ S + + G K L + + + D ++C
Sbjct: 733 RVVLTCELSRVDFPATWYKDGQKVEES-ELLVVKMDGRKHRLILPEAKVQDSGEFECRTE 791
Query: 440 GEKCSTELFVKEPPVLITRPLEDQLV--MVGQRVEFECEVSEEGAQVKWLKDGVELTREE 497
G + V++PPV I P E V + + V CEV E A V+W KDG E+ EE
Sbjct: 792 GVSAFFGVTVQDPPVHIVDPREHVFVHAITSECVMLACEVDREDAPVRWYKDGQEV--EE 849
Query: 498 TFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQA--LAELIVQEKKLEVYQSIADLM 555
+ + +G L++ D G + C +G + I VY S +
Sbjct: 850 SDFVVLENEGPHRRLVLPATQPSDGGEFQ-CVAGDECAYFTVTITDVSSWIVYPSGKVYV 908
Query: 556 VGAK-DQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADY 614
+ ++ V CE+ W K+G+E+V + + V +L + V D +Y
Sbjct: 909 AAVRLERVVLTCELCRPWAEVRWTKDGEEVVESPALLLQKEDTVRRLVLPAVQLEDSGEY 968
Score = 77.4 bits (189), Expect = 8e-14
Identities = 61/239 (25%), Positives = 107/239 (44%), Gaps = 22/239 (9%)
Query: 396 WLKNGQEIQMS---------GSKYIFESIGAKRTLTISQCSLADDAA---YQCVVGGEKC 443
W NG+E++ + +Y E G + L + D A + C G +
Sbjct: 647 WFLNGEELKSNEPEGQVEPGALRYRIEQKGLQHRLILHAVKHQDSGALVGFSCP--GVQD 704
Query: 444 STELFVKEPPVLITRPLEDQLVMV---GQRVEFECEVSEEGAQVKWLKDGVELTREETFK 500
S L ++E PV I P +D++ + +RV CE+S W KDG ++ EE+
Sbjct: 705 SAALTIQESPVHILSP-QDRVSLTFTTSERVVLTCELSRVDFPATWYKDGQKV--EESEL 761
Query: 501 YRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVGA-- 558
K DG++H LI+ EA ++D+G + T G A + VQ+ + + + V A
Sbjct: 762 LVVKMDGRKHRLILPEAKVQDSGEFECRTEGVSAFFGVTVQDPPVHIVDPREHVFVHAIT 821
Query: 559 KDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFV 617
+ + CEV E+ W K+G+E+ + + + G +L + P+D ++ V
Sbjct: 822 SECVMLACEVDREDAPVRWYKDGQEVEESDFVVLENEGPHRRLVLPATQPSDGGEFQCV 880
Score = 71.6 bits (174), Expect = 4e-12
Identities = 155/681 (22%), Positives = 251/681 (36%), Gaps = 94/681 (13%)
Query: 452 PPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREE--------TFKYRF 503
P + LED V G+ F ++S Q W +G EL E +YR
Sbjct: 614 PTARLVAGLEDVQVYDGEDAVFSLDLSTI-IQGTWFLNGEELKSNEPEGQVEPGALRYRI 672
Query: 504 KKDGQRHHLIINEAMLEDAGHYA-LCTSGGQALAELIVQEKKLEVY--QSIADLMVGAKD 560
++ G +H LI++ +D+G G Q A L +QE + + Q L +
Sbjct: 673 EQKGLQHRLILHAVKHQDSGALVGFSCPGVQDSAALTIQESPVHILSPQDRVSLTFTTSE 732
Query: 561 QAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEG 620
+ V CE+S + W K+G+++ + V GR H+L + + D ++ EG
Sbjct: 733 RVVLTCELSRVDFPATWYKDGQKVEESELLVVKMDGRKHRLILPEAKVQDSGEFECRTEG 792
Query: 621 FACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPT 680
+ F V + Q+PP +H+ P R + + + L + + AP
Sbjct: 793 VSA-------FFGVTV-----QDPP-VHIVDP-REHVFVHAITSECVMLACEVDREDAP- 837
Query: 681 VIWQK---------AITQGNKAPAR----PAPDAPEDTGD-----SDEWVFDKKLLCET- 721
V W K + N+ P R PA P D G+ DE + + +
Sbjct: 838 VRWYKDGQEVEESDFVVLENEGPHRRLVLPATQ-PSDGGEFQCVAGDECAYFTVTITDVS 896
Query: 722 ------EGRVRVETTK-DRSIFTVEGAEKEDEGVYT----VTVKNPVGEDQVNLTVKVID 770
G+V V + +R + T E E +T V++P Q TV+ +
Sbjct: 897 SWIVYPSGKVYVAAVRLERVVLTCELCRPWAEVRWTKDGEEVVESPALLLQKEDTVRRLV 956
Query: 771 VPDAPAAPKISNVGEDSCTVQWEPPAY--DGGQPILGYILERKKKKSYRWMRLNFDLIQE 828
+P A ++ + GE C + E ++ +P + I R + L+ E
Sbjct: 957 LP----AVQLEDSGEYLCEIDDESASFTVTVTEPPVRIIYPRDEVTLIAVTLECVVLMCE 1012
Query: 829 LSHE---ARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHL---AVEDVS 882
LS E R +G + V A+ + R P + +P P + A +D +
Sbjct: 1013 LSREDAPVRWYKDG----LEVEESEALVLERDGPRCRLVLPAAQPEDGGEFVCDAGDDSA 1068
Query: 883 DTTVSLKWRPPERV------------GAGGLDGYSVEYCPEGCS-EWVA-ALQGLTEHTS 928
TV++ PPER+ GA G E P G W L+
Sbjct: 1069 FFTVTVT-APPERIVHPAARSLDLHFGAPGRVELRCEVAPAGSQVRWYKDGLEVEASDAL 1127
Query: 929 ILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQL--PRHLRQTIQKK 986
L + PT L + + AG T E +T IL P +Q +
Sbjct: 1128 QLGAEGPTRTLTLPHAQPED-AGEYVCETRHEAITFNVILAEPPVQFLALETTPSPLCVA 1186
Query: 987 VGEPVNLLIPFQGKPRPQVTWTKEGQPL-AGEEVSIRNSPTDTILFIRAARRVHSGTYQV 1045
GEPV L P V W+ G+P+ GE + + +L I+AA H+G Y
Sbjct: 1187 PGEPVVLSCELSRAGAP-VVWSHNGRPVQEGEGLELHAEGPRRVLCIQAAGPAHAGLYTC 1245
Query: 1046 TVRIENMEDKATLVLQVVDKP 1066
+ +QV + P
Sbjct: 1246 QSGAAPGAPSLSFTVQVAEPP 1266
Score = 65.9 bits (159), Expect = 2e-10
Identities = 59/232 (25%), Positives = 95/232 (40%), Gaps = 14/232 (6%)
Query: 391 DAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVV----GGEKCSTE 446
+ E++W G+ + + ++ L + C D Y C G + +
Sbjct: 274 EPEIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLYCQAKDRGLYVCAARNSAGQTLSAVQ 333
Query: 447 LFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKKD 506
L VKEP + TRPL+D EC+V W ++ L KY ++
Sbjct: 334 LHVKEPRLRFTRPLQDVEGREHGIAVLECKVPNSRIPTAWFREDQRLL--PCRKYEQIEE 391
Query: 507 GQRHHLIINEAMLEDAGHYALCTSGGQA--LAELIVQEKKLEVYQSIADLMVGAKDQAVF 564
G LII+ +D G Y LC G+ +A + V+ L+ D++ G + AV
Sbjct: 392 GTVRRLIIHRLKADDDGIY-LCEMRGRVRTVANVTVKGPILKRLPRKLDVLEG--ENAVL 448
Query: 565 KCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSF 616
E + V G W ++G+EL I S G +H L + VT D + +F
Sbjct: 449 LVETLEAGVEGRWSRDGEEL---PVICQSSSGHMHALVLPGVTREDAGEVTF 497
Score = 60.1 bits (144), Expect = 1e-08
Identities = 41/140 (29%), Positives = 65/140 (46%), Gaps = 6/140 (4%)
Query: 395 KWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCSTELFVKEPPV 454
+W G+ ++ G++ G K L +S+ D + G + L V+ P+
Sbjct: 1750 RWELGGRPLR-PGARVRIRQEGKKHILVLSELRAEDAGEVRFQAGPAQSLALLEVEALPL 1808
Query: 455 LITR-PLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLI 513
+ R P ++ V+VG+R E VS G V WL++G EL + KY + G H L+
Sbjct: 1809 QMCRHPPREKTVLVGRRAVLEVTVSRSGGHVCWLREGAELCPGD--KYEMRSHGPTHSLV 1866
Query: 514 INEAMLEDAGHYALCTSGGQ 533
I++ ED G Y C GQ
Sbjct: 1867 IHDVRPEDQGTY--CCQAGQ 1884
Score = 56.2 bits (134), Expect = 2e-07
Identities = 29/87 (33%), Positives = 41/87 (47%)
Query: 8 PVSAFSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLT 67
P+ PR V G AV E R+G V W R G+++ +KY + + G H+L
Sbjct: 1807 PLQMCRHPPREKTVLVGRRAVLEVTVSRSGGHVCWLREGAELCPGDKYEMRSHGPTHSLV 1866
Query: 68 VREVGPADQGSYAVIAGSSKVKFDLKV 94
+ +V P DQG+Y AG L V
Sbjct: 1867 IHDVRPEDQGTYCCQAGQDSTHTRLLV 1893
Score = 54.7 bits (130), Expect = 6e-07
Identities = 25/72 (34%), Positives = 40/72 (55%)
Query: 16 PRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPAD 75
P +EV G A FE E +A V W++ G+ ++ S + L GTR L +R GP+D
Sbjct: 1635 PHDLEVTEGDTATFECELSQALADVTWEKDGNALTPSPRLRLQALGTRRLLQLRRCGPSD 1694
Query: 76 QGSYAVIAGSSK 87
G+Y+ G+++
Sbjct: 1695 AGTYSCAVGTAR 1706
Score = 53.1 bits (126), Expect = 2e-06
Identities = 34/112 (30%), Positives = 46/112 (41%), Gaps = 6/112 (5%)
Query: 11 AFSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVRE 70
A P + VA G P V E RAG V W G + L EG R L ++
Sbjct: 1175 ALETTPSPLCVAPGEPVVLSCELSRAGAPVVWSHNGRPVQEGEGLELHAEGPRRVLCIQA 1234
Query: 71 VGPADQGSYAVIAGSS----KVKFDLKVIEAEKAEPMLAPAPAPAEATGAPG 118
GPA G Y +G++ + F ++V AE ++AP A PG
Sbjct: 1235 AGPAHAGLYTCQSGAAPGAPSLSFTVQV--AEPPVRVVAPEAAQTRVRSTPG 1284
Score = 51.6 bits (122), Expect = 5e-06
Identities = 29/82 (35%), Positives = 36/82 (43%)
Query: 1192 VIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIY 1251
V++G A L C V G P P + W K G L R + L + P D G+Y
Sbjct: 23 VVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHGLLLTAALPTDAGVY 82
Query: 1252 VCRATNLQGEARCECRLEVRVP 1273
VCRA N GEA + V P
Sbjct: 83 VCRARNAAGEAYAAAAVTVLEP 104
Score = 50.1 bits (118), Expect = 1e-05
Identities = 36/125 (28%), Positives = 55/125 (44%), Gaps = 11/125 (8%)
Query: 12 FSKKPRSVEVAAGSPAVFEAET--ERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVR 69
F + PR V V +G+ A + E V V W++GG ++AS + +G H L +
Sbjct: 14 FLRFPRPVRVVSGAEAELKCVVLGEPPPVVV-WEKGGQQLAASERLSFPADGAEHGLLLT 72
Query: 70 EVGPADQGSYAV----IAGSSKVKFDLKVIEAEKAEPMLAPA----PAPAEATGAPGEAP 121
P D G Y AG + + V+E ++P L PA P+P GAP
Sbjct: 73 AALPTDAGVYVCRARNAAGEAYAAAAVTVLEPPASDPELQPAERPLPSPGSGEGAPVFLT 132
Query: 122 APAAE 126
P ++
Sbjct: 133 GPRSQ 137
Score = 48.5 bits (114), Expect = 4e-05
Identities = 36/114 (31%), Positives = 51/114 (44%), Gaps = 6/114 (5%)
Query: 1167 YEPPNYKALDFSEAPS-FTQPLVNRS----VIAGYTAMLCCAVRGSPKPKISWFKNGLDL 1221
++PP D EAP+ +PL V G A C V G P+P+I W G L
Sbjct: 227 HQPPESPPADPDEAPAPVVEPLKCAPKTFWVNEGKHAKFRCYVMGKPEPEIEWHWEGRPL 286
Query: 1222 GEDARFRMF-SKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVRVPQ 1274
D R M+ + G L++ D G+YVC A N G+ +L V+ P+
Sbjct: 287 LPDRRRLMYRDRDGGFVLKVLYCQAKDRGLYVCAARNSAGQTLSAVQLHVKEPR 340
Score = 45.4 bits (106), Expect = 3e-04
Identities = 32/103 (31%), Positives = 44/103 (42%), Gaps = 9/103 (8%)
Query: 1180 APSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQ------ 1233
AP F ++ V+ G +L C G P+P + W K+G+ L E F+ Q
Sbjct: 127 APVFLTGPRSQWVLRGAEVVLTCRAGGLPEPTLYWEKDGMALDEVWDSSHFALQPGRAED 186
Query: 1234 ---GVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVRVP 1273
L L I D G+YVC A N G A+ L+V P
Sbjct: 187 GPGASLALRILAARLPDSGVYVCHARNAHGHAQAGALLQVHQP 229
Score = 43.5 bits (101), Expect = 0.001
Identities = 24/70 (34%), Positives = 34/70 (48%), Gaps = 2/70 (2%)
Query: 12 FSKKPRSVEVAAGSPAVFEAETERAGVK--VRWQRGGSDISASNKYGLATEGTRHTLTVR 69
F ++ + V G E ET R G VRW RGG + ++ +A +G H L +
Sbjct: 1451 FLRRLQDVRAEEGQDVCLEVETGRVGAAGAVRWVRGGQPLPHDSRLSMAQDGHIHRLFIH 1510
Query: 70 EVGPADQGSY 79
V ADQG+Y
Sbjct: 1511 GVILADQGTY 1520
Score = 42.7 bits (99), Expect = 0.002
Identities = 53/224 (23%), Positives = 89/224 (39%), Gaps = 27/224 (12%)
Query: 416 GAKRTLTISQCSLADDAAYQCVV----GGEKCSTELFVKEPP-----------VLITRPL 460
GA L I L D Y C G + L V +PP + PL
Sbjct: 189 GASLALRILAARLPDSGVYVCHARNAHGHAQAGALLQVHQPPESPPADPDEAPAPVVEPL 248
Query: 461 EDQ----LVMVGQRVEFECEV-SEEGAQVKWLKDGVELTREET-FKYRFKKDGQRHHLII 514
+ V G+ +F C V + +++W +G L + YR + G ++
Sbjct: 249 KCAPKTFWVNEGKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLY 308
Query: 515 NEAMLEDAGHY--ALCTSGGQALA--ELIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSD 570
+A +D G Y A S GQ L+ +L V+E +L + + D+ AV +C+V +
Sbjct: 309 CQA--KDRGLYVCAARNSAGQTLSAVQLHVKEPRLRFTRPLQDVEGREHGIAVLECKVPN 366
Query: 571 ENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADY 614
+ W + + L+P + + G V +L I + D+ Y
Sbjct: 367 SRIPTAWFREDQRLLPCRKYEQIEEGTVRRLIIHRLKADDDGIY 410
Score = 40.0 bits (92), Expect = 0.014
Identities = 28/98 (28%), Positives = 40/98 (40%), Gaps = 4/98 (4%)
Query: 17 RSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQ 76
RSV G A FE RW+ GG + + + EG +H L + E+ D
Sbjct: 1726 RSVSAREGDGATFECTVSEVETTGRWELGGRPLRPGARVRIRQEGKKHILVLSELRAEDA 1785
Query: 77 GSYAVIAGSSKVKFDLKVIEAEKAEPMLAPAPAPAEAT 114
G AG ++ L ++E E A P+ P E T
Sbjct: 1786 GEVRFQAGPAQ---SLALLEVE-ALPLQMCRHPPREKT 1819
Score = 39.7 bits (91), Expect = 0.019
Identities = 25/79 (31%), Positives = 37/79 (46%), Gaps = 3/79 (3%)
Query: 16 PRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPAD 75
PR ++V G AV ET AGV+ RW R G ++ + ++ G H L + V D
Sbjct: 435 PRKLDVLEGENAVLLVETLEAGVEGRWSRDGEELPVICQ---SSSGHMHALVLPGVTRED 491
Query: 76 QGSYAVIAGSSKVKFDLKV 94
G G+S+ L+V
Sbjct: 492 AGEVTFSLGNSRTTTLLRV 510
Score = 37.4 bits (85), Expect = 0.092
Identities = 17/65 (26%), Positives = 29/65 (44%)
Query: 32 ETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYAVIAGSSKVKFD 91
E +R VRW + G ++ S+ L EG L + P+D G + +AG F
Sbjct: 830 EVDREDAPVRWYKDGQEVEESDFVVLENEGPHRRLVLPATQPSDGGEFQCVAGDECAYFT 889
Query: 92 LKVIE 96
+ + +
Sbjct: 890 VTITD 894
Score = 36.6 bits (83), Expect = 0.16
Identities = 53/172 (30%), Positives = 66/172 (38%), Gaps = 26/172 (15%)
Query: 925 EHTSILVKDLPTGARLLFRVRAHNMAGPG---APVTTTEPVTVQEILQRPRLQLPR---- 977
EH +L LPT A + + RA N AG A VT EP LQ LP
Sbjct: 66 EHGLLLTAALPTDAGV-YVCRARNAAGEAYAAAAVTVLEPPASDPELQPAERPLPSPGSG 124
Query: 978 -----HLRQTIQKKV--GEPVNLLIPFQGKPRPQVTWTKEGQPL---------AGEEVSI 1021
L + V G V L G P P + W K+G L A +
Sbjct: 125 EGAPVFLTGPRSQWVLRGAEVVLTCRAGGLPEPTLYWEKDGMALDEVWDSSHFALQPGRA 184
Query: 1022 RNSPTDTI-LFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKP-SPPQD 1071
+ P ++ L I AAR SG Y R + +A +LQV P SPP D
Sbjct: 185 EDGPGASLALRILAARLPDSGVYVCHARNAHGHAQAGALLQVHQPPESPPAD 236
Score = 36.2 bits (82), Expect = 0.21
Identities = 53/232 (22%), Positives = 82/232 (35%), Gaps = 39/232 (16%)
Query: 561 QAVFKCEVSDENVRGV-WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADY----- 614
+A KC V E V W K G++L R+ G H L + P D Y
Sbjct: 28 EAELKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHGLLLTAALPTDAGVYVCRAR 87
Query: 615 SFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRI---------PDTIVVVAGN 665
+ E +A +A + +E P +P + L PG P + V+ G
Sbjct: 88 NAAGEAYA---AAAVTVLEPPASD-PELQPAERPLPSPGSGEGAPVFLTGPRSQWVLRGA 143
Query: 666 KLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRV 725
++ L G P PT+ W+K G + + V+D GR
Sbjct: 144 EVVLTCRAGGLPEPTLYWEK-------------------DGMALDEVWDSSHFALQPGRA 184
Query: 726 RVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAA 777
++ + A D GVY +N G Q ++V P++P A
Sbjct: 185 EDGPGASLAL-RILAARLPDSGVYVCHARNAHGHAQAGALLQVHQPPESPPA 235
Score = 35.8 bits (81), Expect = 0.27
Identities = 33/105 (31%), Positives = 48/105 (45%), Gaps = 15/105 (14%)
Query: 440 GEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEV-SEEGAQVKWLKDGVELTREET 498
G++ S F++ P RP+ V+ G E +C V E V W K G +L E
Sbjct: 6 GDQGSPPCFLRFP-----RPVR---VVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASE- 56
Query: 499 FKYRFKKDGQRHHLIINEAMLEDAGHYALC---TSGGQALAELIV 540
+ F DG H L++ A+ DAG Y +C + G+A A V
Sbjct: 57 -RLSFPADGAEHGLLLTAALPTDAGVY-VCRARNAAGEAYAAAAV 99
Score = 35.8 bits (81), Expect = 0.27
Identities = 22/73 (30%), Positives = 30/73 (41%), Gaps = 1/73 (1%)
Query: 378 GHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCV 437
G + L V ++ V WL+ G E+ G KY S G +L I D Y C
Sbjct: 1823 GRRAVLEVTVSRSGGHVCWLREGAEL-CPGDKYEMRSHGPTHSLVIHDVRPEDQGTYCCQ 1881
Query: 438 VGGEKCSTELFVK 450
G + T L V+
Sbjct: 1882 AGQDSTHTRLLVE 1894
Score = 34.7 bits (78), Expect = 0.60
Identities = 29/102 (28%), Positives = 42/102 (41%), Gaps = 5/102 (4%)
Query: 973 LQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPL-AGEEVSIRNSPTDTILF 1031
L+ PR +R G L G+P P V W K GQ L A E +S + L
Sbjct: 15 LRFPRPVRVVS----GAEAELKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHGLL 70
Query: 1032 IRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLR 1073
+ AA +G Y R E A + V++ P+ +L+
Sbjct: 71 LTAALPTDAGVYVCRARNAAGEAYAAAAVTVLEPPASDPELQ 112
Score = 33.9 bits (76), Expect = 1.0
Identities = 28/122 (22%), Positives = 41/122 (33%), Gaps = 29/122 (23%)
Query: 651 CPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDE 710
C R P + VV+G + L + G+P P V+W+K G + A P D +
Sbjct: 13 CFLRFPRPVRVVSGAEAELKCVVLGEPPPVVVWEKG---GQQLAASERLSFPADGAEHG- 68
Query: 711 WVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVID 770
+ A D GVY +N GE V V++
Sbjct: 69 -------------------------LLLTAALPTDAGVYVCRARNAAGEAYAAAAVTVLE 103
Query: 771 VP 772
P
Sbjct: 104 PP 105
Score = 30.8 bits (68), Expect = 8.6
Identities = 19/74 (25%), Positives = 29/74 (39%)
Query: 6 KKPVSAFSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHT 65
K+P F++ + VE AV E + + + W R + KY EGT
Sbjct: 337 KEPRLRFTRPLQDVEGREHGIAVLECKVPNSRIPTAWFREDQRLLPCRKYEQIEEGTVRR 396
Query: 66 LTVREVGPADQGSY 79
L + + D G Y
Sbjct: 397 LIIHRLKADDDGIY 410
>gi|155969693 myomesin family, member 3 [Homo sapiens]
Length = 1437
Score = 119 bits (297), Expect = 2e-26
Identities = 126/513 (24%), Positives = 200/513 (38%), Gaps = 58/513 (11%)
Query: 707 DSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTV 766
+S +W D LL + R + T + S+ V KEDEG+Y V V +P G + + V
Sbjct: 302 ESIQWFRDGSLLRSSRRRKILYTDRQASL-KVSCTYKEDEGLYMVRVPSPFGPREQSTYV 360
Query: 767 KVIDV----PDAPAAP---KISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWM 819
V D P AP +P + +V D + W PP+ G PI Y +ER + +S W+
Sbjct: 361 LVRDAEAENPGAPGSPLNVRCLDVNRDCLILTWAPPSDTRGNPITAYTIERCQGESGEWI 420
Query: 820 RLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQ----------------P 863
+ + ++EG Y RV A++ +G S PS AS+ P
Sbjct: 421 ACHEAPGGTCRCPIQGLVEGQSYRFRVRAISRVGSSVPSKASELVVMGDHDAARRKTEIP 480
Query: 864 F--------------MPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYC 909
F + PS PT++ ++ + V L W P L YS+E
Sbjct: 481 FDLGNKITISTDAFEDTVTIPSPPTNVHASEIREAYVVLAWEEPSPRDRAPLT-YSLEKS 539
Query: 910 PEGCSEWVA-ALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEIL 968
G W A + + V DL +FRVRA N G P +EP+ L
Sbjct: 540 VIGSGTWEAISSESPVRSPRFAVLDLEKKKSYVFRVRAMNQYGLSDPSEPSEPIA----L 595
Query: 969 QRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDT 1028
+ P LP + + V+L P + + E ++ N P
Sbjct: 596 RGPPATLPPPAQVQAFRDTQTSVSLTWDPVKDPELLGYYIYSRKVGTSEWQTVNNKPIQG 655
Query: 1029 ILFIRAARRVHSGTYQVTVRI--------ENMEDKATLVLQVVDKPSPPQDLRVTDAWGL 1080
F R Y+ VR + + V Q + PS P + +
Sbjct: 656 TRFTVPGLRT-GKEYEFCVRSVSEAGVGESSAATEPIRVKQALATPSAPYGFALLNCGKN 714
Query: 1081 NVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTH-CVVPELIIGNGYYFRV 1139
+ + WKPP+ G ++ GY + + D + ++W V + T C V +L G+ Y FR
Sbjct: 715 EMVIGWKPPKRRGGGKILGYFLDQHDSEELDWHAVNQQPIPTRVCKVSDLHEGHFYEFRA 774
Query: 1140 FSQNMVGFSDRAATTK----EPVFIPRPGITYE 1168
+ N G + +A + + +P+PG Y+
Sbjct: 775 RAANWAGVGELSAPSSLFECKEWTMPQPGPPYD 807
Score = 115 bits (288), Expect = 3e-25
Identities = 90/328 (27%), Positives = 139/328 (42%), Gaps = 28/328 (8%)
Query: 736 FTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPK------ISNVGEDSCT 789
FTV G E + V + G + + + I V A A P + N G++
Sbjct: 658 FTVPGLRTGKEYEFCVRSVSEAGVGESSAATEPIRVKQALATPSAPYGFALLNCGKNEMV 717
Query: 790 VQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAV 849
+ W+PP GG ILGY L++ + W +N I + + EG YE R A
Sbjct: 718 IGWKPPKRRGGGKILGYFLDQHDSEELDWHAVNQQPIPTRVCKVSDLHEGHFYEFRARAA 777
Query: 850 NAIGMSRPSPASQPF------MPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDG 903
N G+ S S F MP P P + +V T++ L+W PP +GAG + G
Sbjct: 778 NWAGVGELSAPSSLFECKEWTMP--QPGPPYDVRASEVRATSLVLQWEPPLYMGAGPVTG 835
Query: 904 YSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVT 963
Y V + EG +W G T + V DL G +F+V+A N AG G P T+PV
Sbjct: 836 YHVSFQEEGSEQWKPVTPGPISGTHLRVSDLQPGKSYVFQVQAMNSAGLGQPSMPTDPVL 895
Query: 964 VQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRP---QVTWTKEGQ-PLAGEEV 1019
+++ + I+ V E + + F+ P + W+K+ + PL + V
Sbjct: 896 LED----------KPGAHEIEVGVDEEGFIYLAFEAPEAPDSSEFQWSKDYKGPLDPQRV 945
Query: 1020 SIRNSPTDTILFIRAARRVHSGTYQVTV 1047
I + + + ++ GTY V V
Sbjct: 946 KIEDKVNKSKVILKEPGLEDLGTYSVIV 973
Score = 97.4 bits (241), Expect = 8e-20
Identities = 111/458 (24%), Positives = 174/458 (37%), Gaps = 38/458 (8%)
Query: 751 VTVKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILER 810
+T+ ED V +P P S + E + WE P+ P L Y LE+
Sbjct: 487 ITISTDAFEDTVT-------IPSPPTNVHASEIREAYVVLAWEEPSPRDRAP-LTYSLEK 538
Query: 811 KKKKSYRWMRLNFDL-IQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGP 869
S W ++ + ++ + + Y RV A+N G+S PS S+P GP
Sbjct: 539 SVIGSGTWEAISSESPVRSPRFAVLDLEKKKSYVFRVRAMNQYGLSDPSEPSEPIALRGP 598
Query: 870 PSE---PTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEH 926
P+ P + + T+VSL W P V L GY + G SEW +
Sbjct: 599 PATLPPPAQVQAFRDTQTSVSLTWDP---VKDPELLGYYIYSRKVGTSEWQTVNNKPIQG 655
Query: 927 TSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQ-- 984
T V L TG F VR+ + AG G TEP+ V++ L P L +
Sbjct: 656 TRFTVPGLRTGKEYEFCVRSVSEAGVGESSAATEPIRVKQALATPSAPYGFALLNCGKNE 715
Query: 985 --------KKVGEPVNLLIPFQGKPRPQVTW-TKEGQPLAGEEVSIRNSPTDTILFIRAA 1035
K+ G L ++ W QP+ + + RA
Sbjct: 716 MVIGWKPPKRRGGGKILGYFLDQHDSEELDWHAVNQQPIPTRVCKVSDLHEGHFYEFRAR 775
Query: 1036 RRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNT 1095
+G +++ E K + Q P PP D+R ++ ++ L+W+PP +G
Sbjct: 776 AANWAGVGELSAPSSLFECKEWTMPQ----PGPPYDVRASEVRATSLVLQWEPPLYMGAG 831
Query: 1096 ELWGYTVQKADKKTMEWFTVLE-HYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATT 1154
+ GY V ++ + +W V TH V +L G Y F+V + N G + T
Sbjct: 832 PVTGYHVSFQEEGSEQWKPVTPGPISGTHLRVSDLQPGKSYVFQVQAMNSAGLGQPSMPT 891
Query: 1155 KEPVFIPRP-------GITYEPPNYKALDFSEAPSFTQ 1185
+ +P G+ E Y A + EAP ++
Sbjct: 892 DPVLLEDKPGAHEIEVGVDEEGFIYLAFEAPEAPDSSE 929
Score = 57.4 bits (137), Expect = 9e-08
Identities = 33/108 (30%), Positives = 53/108 (49%), Gaps = 4/108 (3%)
Query: 1168 EPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGL----DLGE 1223
E + L + P F PL + +V T +L C V+ SP P+++W+KN L
Sbjct: 141 EAKELRELCYGRGPWFWIPLRSHAVWEHTTVLLTCTVQASPPPQVTWYKNDTRIDPRLFR 200
Query: 1224 DARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVR 1271
++R+ + G+L+LEIR+ D Y R N G+A ++ VR
Sbjct: 201 AGKYRITNNYGLLSLEIRRCAIEDSATYTVRVKNAHGQASSFAKVLVR 248
Score = 42.0 bits (97), Expect = 0.004
Identities = 33/129 (25%), Positives = 54/129 (41%), Gaps = 11/129 (8%)
Query: 1044 QVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQ 1103
++T+ + ED T+ PSPP ++ ++ V L W+ P L Y+++
Sbjct: 486 KITISTDAFEDTVTI-------PSPPTNVHASEIREAYVVLAWEEPSPRDRAPL-TYSLE 537
Query: 1104 KADKKTMEWFTVLEH--YRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIP 1161
K+ + W + R V +L Y FRV + N G SD + EP+ +
Sbjct: 538 KSVIGSGTWEAISSESPVRSPRFAVLDLEKKKSYVFRVRAMNQYGLSD-PSEPSEPIALR 596
Query: 1162 RPGITYEPP 1170
P T PP
Sbjct: 597 GPPATLPPP 605
Score = 40.8 bits (94), Expect = 0.008
Identities = 32/121 (26%), Positives = 42/121 (34%), Gaps = 29/121 (23%)
Query: 655 IPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFD 714
+PD ++ L L +SGDP P + W K D P D
Sbjct: 1340 LPDVATIMEDKTLCLTCIVSGDPTPEISWLKN-------------DQPVTFLD------- 1379
Query: 715 KKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDA 774
R R+E T+E ED G Y V VKN G + +T+ V D
Sbjct: 1380 ---------RYRMEVRGTEVTITIEKVNSEDSGRYGVFVKNKYGSETGQVTISVFKHGDE 1430
Query: 775 P 775
P
Sbjct: 1431 P 1431
Score = 38.5 bits (88), Expect = 0.041
Identities = 24/80 (30%), Positives = 35/80 (43%)
Query: 1191 SVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGI 1250
+++ T L C V G P P+ISW KN + R+RM + +T+ I K D G
Sbjct: 1345 TIMEDKTLCLTCIVSGDPTPEISWLKNDQPVTFLDRYRMEVRGTEVTITIEKVNSEDSGR 1404
Query: 1251 YVCRATNLQGEARCECRLEV 1270
Y N G + + V
Sbjct: 1405 YGVFVKNKYGSETGQVTISV 1424
Score = 32.3 bits (72), Expect = 3.0
Identities = 22/108 (20%), Positives = 45/108 (41%), Gaps = 1/108 (0%)
Query: 967 ILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAG-EEVSIRNSP 1025
I+++ R ++ R L + + L G P P+++W K QP+ + +
Sbjct: 1328 IIEKNRAKVVRGLPDVATIMEDKTLCLTCIVSGDPTPEISWLKNDQPVTFLDRYRMEVRG 1387
Query: 1026 TDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLR 1073
T+ + I SG Y V V+ + + + + V P++L+
Sbjct: 1388 TEVTITIEKVNSEDSGRYGVFVKNKYGSETGQVTISVFKHGDEPKELK 1435
Score = 31.6 bits (70), Expect = 5.1
Identities = 23/86 (26%), Positives = 37/86 (43%), Gaps = 2/86 (2%)
Query: 350 KRLKGMRRDEKKSTAFQKKLEPAYQVSKGHKIRLT-VELADHDAEVKWLKNGQEIQMSGS 408
+RLK + EK + L + + + LT + D E+ WLKN Q +
Sbjct: 1321 QRLKTLAIIEKNRAKVVRGLPDVATIMEDKTLCLTCIVSGDPTPEISWLKNDQPVTFL-D 1379
Query: 409 KYIFESIGAKRTLTISQCSLADDAAY 434
+Y E G + T+TI + + D Y
Sbjct: 1380 RYRMEVRGTEVTITIEKVNSEDSGRY 1405
Score = 31.2 bits (69), Expect = 6.6
Identities = 11/43 (25%), Positives = 22/43 (51%)
Query: 39 KVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYAV 81
++ W + ++ ++Y + GT T+T+ +V D G Y V
Sbjct: 1365 EISWLKNDQPVTFLDRYRMEVRGTEVTITIEKVNSEDSGRYGV 1407
>gi|110349721 titin isoform novex-3 [Homo sapiens]
Length = 5604
Score = 118 bits (295), Expect = 4e-26
Identities = 111/440 (25%), Positives = 189/440 (42%), Gaps = 60/440 (13%)
Query: 395 KWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCSTELFVKEPPV 454
KWLKNG EI+ S K + +L I D A Y V G + L+V+ +
Sbjct: 3000 KWLKNGVEIK-STDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHI 3058
Query: 455 LITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLII 514
+ ++D V+ +R FECEVSE V+W+KD EL + T + + +K+ H L+I
Sbjct: 3059 EFRKHIKDIKVLEKKRAMFECEVSEPDITVQWMKDDQEL--QITDRIKIQKEKYVHRLLI 3116
Query: 515 NEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDENVR 574
+ DAG Y + G + A+L V+ + + + ++ V K +AV + EV++++V
Sbjct: 3117 PSTRMSDAGKYTVVAGGNVSTAKLFVEGRDVRIRSIKKEVQVIEKQRAVVEFEVNEDDVD 3176
Query: 575 GVWLKNGKEL--VPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFM 632
W K+G E+ R K R+H++ I + +D +Y+FV +++
Sbjct: 3177 AHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVTL----- 3231
Query: 633 EVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNK 692
+V EPP++ + + V +G R ISG P P + W K
Sbjct: 3232 -----YVNAPEPPQVLQEL-----QPVTVQSGKPARFCAVISGRPQPKISWYK------- 3274
Query: 693 APARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVT 752
+E + C+ + ++ ++ +E A ED VYT
Sbjct: 3275 ----------------EEQLLSTGFKCKF-----LHDGQEYTLLLIE-AFPEDAAVYTCE 3312
Query: 753 VKNPVG--EDQVNLTVKVIDV--PDAPA---APKISNVGEDSCTVQWEPPAY----DGGQ 801
KN G +L+V+V +V PD P I +D+ T + +P + G
Sbjct: 3313 AKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTD 3372
Query: 802 PILGYILERKKKKSYRWMRL 821
+ + + KK K R+ R+
Sbjct: 3373 LKVSWYSKDKKIKPSRFFRM 3392
Score = 117 bits (294), Expect = 5e-26
Identities = 82/248 (33%), Positives = 119/248 (47%), Gaps = 8/248 (3%)
Query: 386 ELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCST 445
E++ + WLKNG EI+MS K+ G L I S D A Y V G ++ S
Sbjct: 2904 EVSHFNVPSMWLKNGVEIEMS-EKFKIVVQGKLHQLIIMNTSTEDSAEYTFVCGNDQVSA 2962
Query: 446 ELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKK 505
L V P++IT L+D + FE V+ EG KWLK+GVE+ + + R KK
Sbjct: 2963 TLTVT--PIMITSMLKDINAEEKDTITFEVTVNYEGISYKWLKNGVEIKSTDKCQMRTKK 3020
Query: 506 DGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFK 565
H L I DA Y + A L V+ + +E + I D+ V K +A+F+
Sbjct: 3021 --LTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIEFRKHIKDIKVLEKKRAMFE 3078
Query: 566 CEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNL 625
CEVS+ ++ W+K+ +EL RIK+ VH+L I +D Y+ V G N+
Sbjct: 3079 CEVSEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVAGG---NV 3135
Query: 626 SAKLHFME 633
S F+E
Sbjct: 3136 STAKLFVE 3143
Score = 115 bits (289), Expect = 2e-25
Identities = 84/310 (27%), Positives = 138/310 (44%), Gaps = 12/310 (3%)
Query: 360 KKSTAFQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKR 419
K+ F ++L+ K E ++ +VKW K+G E+ G KY S
Sbjct: 2171 KQLITFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVH-EGDKYRMHSDRKVH 2229
Query: 420 TLTISQCSLADDAAYQCVVGGE---KCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECE 476
L+I +D Y CV+ + K + +L V+ V + L+D V E EC
Sbjct: 2230 FLSILTIDTSDAEDYSCVLVEDENVKTTAKLIVEGAVVEFVKELQDIEVPESYSGELECI 2289
Query: 477 VSEEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALA 536
VS E + KW + VEL + KY R +L + + ED G Y+ G +
Sbjct: 2290 VSPENIEGKWYHNDVEL--KSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGKKTTC 2347
Query: 537 ELIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIG 596
+L ++ + + + Q ++D V D + +VS E+V GVW+K+G+E+ P R+ +
Sbjct: 2348 KLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHIVIDK 2407
Query: 597 RVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQ-----EPPKIHLDC 651
+ H L I+D+T D +YSF + S ++ V + P + E K L+C
Sbjct: 2408 QSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVDV-ITPLKDVNVIEGTKAVLEC 2466
Query: 652 PGRIPDTIVV 661
+PD V
Sbjct: 2467 KVSVPDVTSV 2476
Score = 107 bits (268), Expect = 6e-23
Identities = 72/235 (30%), Positives = 117/235 (49%), Gaps = 8/235 (3%)
Query: 384 TVELADHDAE-VKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEK 442
TVEL + + V+W+KNG ++ S KY G +L I C++ D++ Y +G
Sbjct: 2727 TVELTHPNVKGVQWIKNGVVLE-SNEKYAISVKGTIYSLRIKNCAIVDESVYGFRLGRLG 2785
Query: 443 CSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYR 502
S L V+ V I + +D + V FE VS + VKW VE+ + K+R
Sbjct: 2786 ASARLHVET--VKIIKKPKDVTALENATVAFEVSVSHDTVPVKWFHKSVEIKPSD--KHR 2841
Query: 503 FKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQA 562
+ + H L++ DAG Y + A+L V+ L + +++ ++ V A
Sbjct: 2842 LVSERKVHKLMLQNISPSDAGEYTAVVGQLECKAKLFVET--LHITKTMKNIEVPETKTA 2899
Query: 563 VFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFV 617
F+CEVS NV +WLKNG E+ + K+ G++H+L I + + D A+Y+FV
Sbjct: 2900 SFECEVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFV 2954
Score = 99.4 bits (246), Expect = 2e-20
Identities = 77/249 (30%), Positives = 111/249 (44%), Gaps = 13/249 (5%)
Query: 391 DAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCV---VGGEKCSTEL 447
D E +W KNG +I+ S Y + L I + D A+ + GE S
Sbjct: 2106 DPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAF 2165
Query: 448 FVKEPPVLITRPLEDQLVMVGQR---VEFECEVSEEGAQVKWLKDGVELTREETFKYRFK 504
+ + LIT E Q V+ ++ FECE SE +VKW KDG+E+ E KYR
Sbjct: 2166 LLVQAKQLITFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEV--HEGDKYRMH 2223
Query: 505 KDGQRHHLIINEAMLEDAGHYALC---TSGGQALAELIVQEKKLEVYQSIADLMVGAKDQ 561
D + H L I DA Y+ + A+LIV+ +E + + D+ V
Sbjct: 2224 SDRKVHFLSILTIDTSDAEDYSCVLVEDENVKTTAKLIVEGAVVEFVKELQDIEVPESYS 2283
Query: 562 AVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEG- 620
+C VS EN+ G W N EL + + ++ LT+ DVT D+ +YSFV +G
Sbjct: 2284 GELECIVSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGK 2343
Query: 621 -FACNLSAK 628
C L K
Sbjct: 2344 KTTCKLKMK 2352
Score = 91.3 bits (225), Expect = 5e-18
Identities = 65/244 (26%), Positives = 113/244 (46%), Gaps = 6/244 (2%)
Query: 374 QVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAA 433
+V +G ++L V+++ E W+K+GQE+Q S +I L I + D
Sbjct: 2366 KVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHIVID-KQSHMLLIEDMTKEDAGN 2424
Query: 434 YQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVS-EEGAQVKWLKDGVE 492
Y + ST V V + PL+D V+ G + EC+VS + VKW + +
Sbjct: 2425 YSFTIPALGLSTSGRVSVYSVDVITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQ 2484
Query: 493 LTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIA 552
+ ++ + K G + L+IN D G Y L + L V+ K+++ + +
Sbjct: 2485 IKPDDRVQAIVK--GTKQRLVINRTHASDEGPYKLIVGRVETNCNLSVE--KIKIIRGLR 2540
Query: 553 DLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEA 612
DL VF+ E+S + +W KE+ P S+ K+ G+++KLT+ ++ DE
Sbjct: 2541 DLTCTETQNVVFEVELSHSGIDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEG 2600
Query: 613 DYSF 616
Y+F
Sbjct: 2601 KYTF 2604
Score = 88.2 bits (217), Expect = 5e-17
Identities = 100/421 (23%), Positives = 169/421 (40%), Gaps = 41/421 (9%)
Query: 359 EKKSTAFQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAK 418
E + F+K ++ + K + E+++ D V+W+K+ QE+Q++ I +
Sbjct: 3054 EARHIEFRKHIKDIKVLEK-KRAMFECEVSEPDITVQWMKDDQELQITDRIKIQKEKYVH 3112
Query: 419 RTLTISQCSLADDAAYQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVS 478
R L I ++D Y V GG + +LFV+ V I ++ V+ QR E EV+
Sbjct: 3113 RLL-IPSTRMSDAGKYTVVAGGNVSTAKLFVEGRDVRIRSIKKEVQVIEKQRAVVEFEVN 3171
Query: 479 EEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAEL 538
E+ W KDG+E+ + ++++ + + H + I+E DAG Y ++ L
Sbjct: 3172 EDDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVTL 3231
Query: 539 IVQ-EKKLEVYQSIADLMVGAKDQAVFKCEVSDENVRGV-WLKNGKELVPDSRIKVSHIG 596
V + +V Q + + V + A F +S + W K + L + K H G
Sbjct: 3232 YVNAPEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDG 3291
Query: 597 RVHKLTIDDVTPADEADYSFVPEG--FACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGR 654
+ + L + + P D A Y+ + SA L +EV P QE P
Sbjct: 3292 QEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLS-VEVPEVVSPDQEMPVYPPAIITP 3350
Query: 655 IPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFD 714
+ DT V G R +SG + K D
Sbjct: 3351 LQDT-VTSEGQPARFQCRVSGTDLKVSWYSK----------------------------D 3381
Query: 715 KKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKV-IDVPD 773
KK+ + R+ +D + A EDEG YT N VG QV+ T + ++ P+
Sbjct: 3382 KKI--KPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVG--QVSSTANLSLEAPE 3437
Query: 774 A 774
+
Sbjct: 3438 S 3438
Score = 86.7 bits (213), Expect = 1e-16
Identities = 71/263 (26%), Positives = 119/263 (45%), Gaps = 10/263 (3%)
Query: 375 VSKGHKIRLTVELADHDA-EVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAA 433
V +G K L +++ D VKW N ++I+ G K+ L I++ +D+
Sbjct: 2456 VIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVK-GTKQRLVINRTHASDEGP 2514
Query: 434 YQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVEL 493
Y+ +VG + + L V++ + I R L D Q V FE E+S G V W E+
Sbjct: 2515 YKLIVGRVETNCNLSVEK--IKIIRGLRDLTCTETQNVVFEVELSHSGIDVLWNFKDKEI 2572
Query: 494 TREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIAD 553
+ + KY+ + G+ + L + M +D G Y +L V + + + D
Sbjct: 2573 --KPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTFYAGENMTSGKLTVAGGAIS--KPLTD 2628
Query: 554 LMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEAD 613
V +AVF+CEV++ + +G WL++GK L + I+ G +L I D +
Sbjct: 2629 QTVAESQEAVFECEVANPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGE 2688
Query: 614 YSFVPEGFACNLSAKLHFMEVKI 636
Y++ + SAKL VKI
Sbjct: 2689 YTY--KVATSKTSAKLKVEAVKI 2709
Score = 77.4 bits (189), Expect = 8e-14
Identities = 65/250 (26%), Positives = 112/250 (44%), Gaps = 8/250 (3%)
Query: 375 VSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAY 434
V++ + E+A+ D++ +WL++G+ + ++ + ES G KR L I+ L D Y
Sbjct: 2631 VAESQEAVFECEVANPDSKGEWLRDGKHLPLTNN-IRSESDGHKRRLIIAATKLDDIGEY 2689
Query: 435 QCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQ-VKWLKDGVEL 493
V K S +L V+ V I + L++ V Q F E++ + V+W+K+GV L
Sbjct: 2690 TYKVATSKTSAKLKVEA--VKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVL 2747
Query: 494 TREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIAD 553
E KY G + L I + D Y A A L V+ K + + D
Sbjct: 2748 ESNE--KYAISVKGTIYSLRIKNCAIVDESVYGFRLGRLGASARLHVETVK--IIKKPKD 2803
Query: 554 LMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEAD 613
+ F+ VS + V W E+ P + ++ +VHKL + +++P+D +
Sbjct: 2804 VTALENATVAFEVSVSHDTVPVKWFHKSVEIKPSDKHRLVSERKVHKLMLQNISPSDAGE 2863
Query: 614 YSFVPEGFAC 623
Y+ V C
Sbjct: 2864 YTAVVGQLEC 2873
Score = 66.6 bits (161), Expect = 1e-10
Identities = 166/772 (21%), Positives = 275/772 (35%), Gaps = 163/772 (21%)
Query: 577 WLKNGKELVPD--SRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEV 634
W +G+++V D ++ + G L I TP+D +++ V + A S + +
Sbjct: 1490 WFHDGQQIVNDYTHKVVIKEDG-TQSLIIVPATPSDSGEWTVVAQNRAGRSSISVI---L 1545
Query: 635 KIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAP 694
++ V Q P + + G++L + V +G+P P ++W K
Sbjct: 1546 TVEAVEHQVKPMFVEKLKN-----VNIKEGSRLEMKVRATGNPNPDIVWLK--------- 1591
Query: 695 ARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVK 754
+SD V K ++R+E TK + ++ +D YT T
Sbjct: 1592 ------------NSDIIVPHKY------PKIRIEGTKGEAALKIDSTVSQDSAWYTATAI 1633
Query: 755 NPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKK 814
N G D V V V++ P +P I+ R
Sbjct: 1634 NKAGRDTTRCKVNV--------------------EVEFAEP-----EPERKLIIPRG--- 1665
Query: 815 SYRWMRLNFDLIQ--ELSHEARRMIEGVVYEMRVYA-------VNAIGMSRPSPASQP-- 863
+YR + ++ L + + EG +Y+ + ++ + R PA
Sbjct: 1666 TYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGPAHFECR 1725
Query: 864 FMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPE-GCSEWVAALQG 922
PIG P+ + D + + R G LD Y V Y + G A +
Sbjct: 1726 LTPIGDPTMVVEW-LHDGKPLEAANRLRMINEFGYCSLD-YGVAYSRDSGIITCRATNKY 1783
Query: 923 LTEHTS--ILVKD---------LPTGARLLFRVRA-HNMAGPGAPVTTTEPVTVQEILQR 970
T+HTS ++VKD LP G + L R+ MA GA T T Q+ Q+
Sbjct: 1784 GTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVT---TDQKEKQK 1840
Query: 971 PRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLA-GEEVSIRNSPTDTI 1029
P + L + ++ GE G P+P+V W GQ + + +R D I
Sbjct: 1841 PDIVL---YPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRY---DGI 1894
Query: 1030 LFIRAARRVHSGTYQVTVRIEN----MEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALE 1085
++ T +V V EN +E K L +Q +D R L A E
Sbjct: 1895 HYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQ------QREDFRSV----LRRAPE 1944
Query: 1086 WKPPQDVGNTELWGYTVQKADK-----KTMEWFTVLEHYRRTHCVVPELI---------- 1130
+P V + VQK D+ +T E + R TH VPE
Sbjct: 1945 PRPEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKVPEESEELRSKFKRR 2004
Query: 1131 IGNGYYFRV---------------------------FSQNMVGFSDRAATTKEPVFIPRP 1163
GYY + +++ + +A + + IP
Sbjct: 2005 TEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIP-- 2062
Query: 1164 GITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGE 1223
T++P + EAP + + +++V G A V G P P+ W+KNG+ +
Sbjct: 2063 --TFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIER 2120
Query: 1224 DAR-FRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVRVPQ 1274
R + + + V L IR D + +A N+ GE L V+ Q
Sbjct: 2121 SDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQ 2172
Score = 63.2 bits (152), Expect = 2e-09
Identities = 81/335 (24%), Positives = 134/335 (40%), Gaps = 41/335 (12%)
Query: 950 AGPG---APVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVT 1006
AGPG AP T+PV VQ++++ G V G P+P V
Sbjct: 1074 AGPGEPAAPYFITKPV-VQKLVE------------------GGSVVFGCQVGGNPKPHVY 1114
Query: 1007 WTKEGQPLAGE---EVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVV 1063
W K G PL +VS + L I +G Y + VR ++ E A+ L
Sbjct: 1115 WKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEE 1174
Query: 1064 DKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKK-TMEWFTVLEHYRRT 1122
+ + V + P+ VG T G+ + +K+ E + + +
Sbjct: 1175 ADYELLMKSQQEMLYQTQVTAFVQEPK-VGETAP-GFVYSEYEKEYEKEQALIRKKMAKD 1232
Query: 1123 HCVVPELIIGNGYYFRVFSQNMVGFSDRAA--TTKEPVFIPRPGITYEPPNYKALDFSEA 1180
VV + ++ F + ++ + TT E + + + A+D SE+
Sbjct: 1233 TVVVRTYVEDQEFHISSFEERLIKEIEYRIIKTTLEEL------LEEDGEEKMAVDISES 1286
Query: 1181 PS----FTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRM-FSKQGV 1235
+ F + N ++ G C + G P PKI+W+K+G + R++M F + G
Sbjct: 1287 EAVESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGR 1346
Query: 1236 LTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
+L I P D GIY A+N++G A C +L V
Sbjct: 1347 ASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYV 1381
Score = 60.5 bits (145), Expect = 1e-08
Identities = 55/197 (27%), Positives = 95/197 (48%), Gaps = 10/197 (5%)
Query: 451 EPPVLITRPLEDQLVMVGQRVEFECEV-SEEGAQVKWLKDGVELTREETFKYRFKKDGQR 509
E P + R ++ Q V G F V + + +W K+GV++ R + + + +D
Sbjct: 2076 EAPKIFER-IQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNV- 2133
Query: 510 HHLIINEAMLEDAGHY---ALCTSG-GQALAELIVQEKKLEVY-QSIADLMVGAKD-QAV 563
L+I + ED+ A+ +G + A L+VQ K+L + Q + D++ KD A
Sbjct: 2134 CELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMAT 2193
Query: 564 FKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFV-PEGFA 622
F+CE S+ V+ W K+G E+ + ++ +VH L+I + +D DYS V E
Sbjct: 2194 FECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDEN 2253
Query: 623 CNLSAKLHFMEVKIDFV 639
+AKL ++FV
Sbjct: 2254 VKTTAKLIVEGAVVEFV 2270
Score = 58.5 bits (140), Expect = 4e-08
Identities = 33/94 (35%), Positives = 47/94 (50%), Gaps = 1/94 (1%)
Query: 1181 PSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEI 1240
PSF +PL R V T V G P P + W++N L D R +M V +LEI
Sbjct: 5183 PSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYRNKSLLEPDERIKMERVGNVCSLEI 5242
Query: 1241 RKPCPFDGGIYVCRATNLQGEARCECRLEVRVPQ 1274
+GG Y+C A N+ GEA+ +++ +PQ
Sbjct: 5243 SNIQKGEGGEYMCHAVNIIGEAKSFANVDI-MPQ 5275
Score = 55.8 bits (133), Expect = 3e-07
Identities = 29/89 (32%), Positives = 45/89 (50%), Gaps = 1/89 (1%)
Query: 1177 FSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGED-ARFRMFSKQGV 1235
F P F P+ + + A+ C+V G P P++ W+K + + D ++ + ++G
Sbjct: 5376 FEMPPRFIMPICDFKIPENSDAVFKCSVIGIPTPEVKWYKEYMCIEPDNIKYVISEEKGS 5435
Query: 1236 LTLEIRKPCPFDGGIYVCRATNLQGEARC 1264
TL+IR C D Y CRA N GEA C
Sbjct: 5436 HTLKIRNVCLSDSATYRCRAVNCVGEAIC 5464
Score = 54.7 bits (130), Expect = 6e-07
Identities = 27/94 (28%), Positives = 44/94 (46%)
Query: 1181 PSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEI 1240
P+ L N +VI G + L C + G P P ++W++ + F++ + G+ L I
Sbjct: 943 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMI 1002
Query: 1241 RKPCPFDGGIYVCRATNLQGEARCECRLEVRVPQ 1274
R+ D G + C A N G C L V+V +
Sbjct: 1003 REAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSE 1036
Score = 54.3 bits (129), Expect = 7e-07
Identities = 31/96 (32%), Positives = 42/96 (43%)
Query: 1179 EAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTL 1238
E P Q L +V +G A C + G P+PKISW+K L + + TL
Sbjct: 3237 EPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTL 3296
Query: 1239 EIRKPCPFDGGIYVCRATNLQGEARCECRLEVRVPQ 1274
+ + P D +Y C A N G A L V VP+
Sbjct: 3297 LLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPE 3332
Score = 50.4 bits (119), Expect = 1e-05
Identities = 69/335 (20%), Positives = 123/335 (36%), Gaps = 76/335 (22%)
Query: 969 QRPRLQLPRHLRQTIQKKV--GEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNS-- 1024
+RP+ P L++ ++V G+ N + FQG P+P VTW P+ + I +S
Sbjct: 3937 KRPQRCPPSFLQEIESQEVYEGDSCNFVCHFQGYPQPIVTWYNNDMPIPRNQNFIIHSLE 3996
Query: 1025 -----------------------------PTDTILFIRAARRVHSGTYQVTVRIENMEDK 1055
T ++L ++A ++ ++V V + ++++
Sbjct: 3997 NYSILTLSSVHHQNEGSITCVLFNQYGTVKTTSMLKVKAKQKHDVKAHKVPVFHDYLDEE 4056
Query: 1056 ATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQ----------KA 1105
L L + L++ P G+TEL + V+ +
Sbjct: 4057 EELALVFDQAKGAHPSMSQEGQTNLHLLKTNPPVPPSGDTELLSFPVEIQVTAATPIPEQ 4116
Query: 1106 DKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGI 1165
DK++ E F E + +P+ D+ + + F+ I
Sbjct: 4117 DKESKEVFQTEELEPKA---MPQ--------------------DQVTQSPKHRFVFLSDI 4153
Query: 1166 TYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDA 1225
T EPP E P + S+I L C + G P+P ++WF+NG+ L ++
Sbjct: 4154 TNEPPKM----LQEMPKHARCREGDSII------LECLISGEPQPVVTWFQNGVLLKQNQ 4203
Query: 1226 RFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQG 1260
+F+ L I+ D G Y C A N G
Sbjct: 4204 KFQFEEVNCSHQLYIKDVNSQDSGKYKCVAENNSG 4238
Score = 50.1 bits (118), Expect = 1e-05
Identities = 53/164 (32%), Positives = 80/164 (48%), Gaps = 20/164 (12%)
Query: 393 EVKWLKNGQEIQMS---GSKYIFESIGAKRTLTISQCSLADDAAYQCVV---GGEKCST- 445
EV W ++GQ I S G + F AK LTI + A+ Y G+ ST
Sbjct: 36 EVSWFRDGQVISTSTLPGVQISFSDGRAK--LTIPAVTKANSGRYSLKATNGSGQATSTA 93
Query: 446 ELFVKE---PPVLITRPLEDQLVMVGQRVEFECEVSEEGAQV-KWLKDGVELTREETFKY 501
EL VK PP + R L+ V G +V + V+ V K+ +DG E+ + + +
Sbjct: 94 ELLVKAETAPPNFVQR-LQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEI--QSSLDF 150
Query: 502 RFKKDGQRHHLIINEAMLEDAGHYAL--CTSGGQA--LAELIVQ 541
+ ++G + L+I EA ED+G Y++ S G+A AEL+VQ
Sbjct: 151 QISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194
Score = 48.5 bits (114), Expect = 4e-05
Identities = 24/81 (29%), Positives = 37/81 (45%)
Query: 14 KKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGP 73
KKP+ V + FE V V+W +I S+K+ L +E H L ++ + P
Sbjct: 2799 KKPKDVTALENATVAFEVSVSHDTVPVKWFHKSVEIKPSDKHRLVSERKVHKLMLQNISP 2858
Query: 74 ADQGSYAVIAGSSKVKFDLKV 94
+D G Y + G + K L V
Sbjct: 2859 SDAGEYTAVVGQLECKAKLFV 2879
Score = 48.1 bits (113), Expect = 5e-05
Identities = 30/96 (31%), Positives = 47/96 (48%), Gaps = 2/96 (2%)
Query: 1178 SEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDA--RFRMFSKQGV 1235
++AP+FTQPL + V+ G TA + G P P++SWF++G + ++ G
Sbjct: 3 TQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGR 62
Query: 1236 LTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVR 1271
L I + G Y +ATN G+A L V+
Sbjct: 63 AKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98
Score = 45.8 bits (107), Expect = 3e-04
Identities = 22/82 (26%), Positives = 35/82 (42%)
Query: 13 SKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVG 72
+K +++EV A FE E V W + G +I S K+ + +G H L +
Sbjct: 2885 TKTMKNIEVPETKTASFECEVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTS 2944
Query: 73 PADQGSYAVIAGSSKVKFDLKV 94
D Y + G+ +V L V
Sbjct: 2945 TEDSAEYTFVCGNDQVSATLTV 2966
Score = 44.3 bits (103), Expect = 8e-04
Identities = 26/91 (28%), Positives = 43/91 (47%)
Query: 1181 PSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEI 1240
P+F Q L + +V G L V G P P + ++++G ++ F++ + + +L I
Sbjct: 104 PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLI 163
Query: 1241 RKPCPFDGGIYVCRATNLQGEARCECRLEVR 1271
+ P D G Y ATN G A L V+
Sbjct: 164 AEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194
Score = 43.5 bits (101), Expect = 0.001
Identities = 23/76 (30%), Positives = 35/76 (46%)
Query: 28 VFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYAVIAGSSK 87
VFE E +G+ V W +I S+KY + G + LTV + D+G Y AG +
Sbjct: 2551 VFEVELSHSGIDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTFYAGENM 2610
Query: 88 VKFDLKVIEAEKAEPM 103
L V ++P+
Sbjct: 2611 TSGKLTVAGGAISKPL 2626
Score = 42.4 bits (98), Expect = 0.003
Identities = 29/95 (30%), Positives = 43/95 (45%), Gaps = 6/95 (6%)
Query: 1181 PSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVL---- 1236
PSFTQ L + V+ G + C + P P+++WF N + R R+ + L
Sbjct: 3504 PSFTQKLTFKYVLEGEPVVFTCRLIACPTPEMTWFHNNRPIPTGLR-RIIKAESDLHHHS 3562
Query: 1237 -TLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
+LEI++ D G Y A N +G A L V
Sbjct: 3563 SSLEIKRVQDRDSGSYRLLAINSEGSAESTASLLV 3597
Score = 42.0 bits (97), Expect = 0.004
Identities = 33/111 (29%), Positives = 51/111 (45%), Gaps = 14/111 (12%)
Query: 453 PVLITRPLEDQLVMVGQRVEFECEVS-EEGAQVKWLKDGVELTREETFKYRFKKDGQRHH 511
P IT+P+ +LV G V F C+V V W K GV LT +K + K
Sbjct: 1082 PYFITKPVVQKLVEGGS-VVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECK 1140
Query: 512 LIINEAMLEDAGHYALC-------TSGGQALA-----ELIVQEKKLEVYQS 550
L+I+ +DAG Y + TS +L EL+++ ++ +YQ+
Sbjct: 1141 LVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLMKSQQEMLYQT 1191
Score = 42.0 bits (97), Expect = 0.004
Identities = 30/83 (36%), Positives = 39/83 (46%), Gaps = 2/83 (2%)
Query: 1181 PSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRM-FSKQGVLTLE 1239
P F + + + G A C VRGSP+P + W+K+G L + RF + S G L
Sbjct: 5514 PRFIKGISDCYAPIGTAAYFQCLVRGSPRPTVYWYKDG-KLVQGRRFTVEESGTGFHNLF 5572
Query: 1240 IRKPCPFDGGIYVCRATNLQGEA 1262
I D G Y C ATN G A
Sbjct: 5573 ITSLVKSDEGEYRCVATNKSGMA 5595
Score = 41.6 bits (96), Expect = 0.005
Identities = 21/86 (24%), Positives = 38/86 (44%)
Query: 9 VSAFSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTV 68
V F K+ + +EV E ++ +W ++ ++ KY + + R LTV
Sbjct: 2266 VVEFVKELQDIEVPESYSGELECIVSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTV 2325
Query: 69 REVGPADQGSYAVIAGSSKVKFDLKV 94
++V DQG Y+ + K LK+
Sbjct: 2326 KDVTKEDQGEYSFVIDGKKTTCKLKM 2351
Score = 41.6 bits (96), Expect = 0.005
Identities = 26/94 (27%), Positives = 38/94 (40%), Gaps = 1/94 (1%)
Query: 1181 PSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEI 1240
P+ PL + G A C V G+ K+SW+ + FRM + LEI
Sbjct: 3345 PAIITPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEI 3403
Query: 1241 RKPCPFDGGIYVCRATNLQGEARCECRLEVRVPQ 1274
+ P D G Y A+N G+ L + P+
Sbjct: 3404 AEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPE 3437
Score = 41.2 bits (95), Expect = 0.006
Identities = 23/105 (21%), Positives = 46/105 (43%), Gaps = 16/105 (15%)
Query: 12 FSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREV 71
F K + ++V A+FE E + V+W + ++ +++ + E H L +
Sbjct: 3060 FRKHIKDIKVLEKKRAMFECEVSEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPST 3119
Query: 72 GPADQGSYAVIAGSS----------------KVKFDLKVIEAEKA 100
+D G Y V+AG + +K +++VIE ++A
Sbjct: 3120 RMSDAGKYTVVAGGNVSTAKLFVEGRDVRIRSIKKEVQVIEKQRA 3164
Score = 41.2 bits (95), Expect = 0.006
Identities = 22/94 (23%), Positives = 41/94 (43%)
Query: 1181 PSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEI 1240
PSF Q + ++ V G + C +G P+P ++W+ N + + + F + S + L +
Sbjct: 3944 PSFLQEIESQEVYEGDSCNFVCHFQGYPQPIVTWYNNDMPIPRNQNFIIHSLENYSILTL 4003
Query: 1241 RKPCPFDGGIYVCRATNLQGEARCECRLEVRVPQ 1274
+ G C N G + L+V+ Q
Sbjct: 4004 SSVHHQNEGSITCVLFNQYGTVKTTSMLKVKAKQ 4037
Score = 40.8 bits (94), Expect = 0.008
Identities = 38/167 (22%), Positives = 69/167 (41%), Gaps = 8/167 (4%)
Query: 457 TRPLEDQLVMVGQRVEFECEVSE-EGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIIN 515
T+PL+ +V+ G FE +S +V W +DG ++ + R L I
Sbjct: 9 TQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIP 68
Query: 516 EAMLEDAGHYALCTSGGQ----ALAELIVQEKKL--EVYQSIADLMVGAKDQAVFKCEVS 569
++G Y+L + G + AEL+V+ + Q + + V Q + V+
Sbjct: 69 AVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVT 128
Query: 570 DENVRGV-WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYS 615
V + ++G E+ ++S G ++ L I + P D YS
Sbjct: 129 GIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYS 175
Score = 40.8 bits (94), Expect = 0.008
Identities = 21/70 (30%), Positives = 36/70 (51%), Gaps = 1/70 (1%)
Query: 27 AVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYA-VIAGS 85
A FE ET VKV+W + G ++ +KY + ++ H L++ + +D Y+ V+
Sbjct: 2192 ATFECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVED 2251
Query: 86 SKVKFDLKVI 95
VK K+I
Sbjct: 2252 ENVKTTAKLI 2261
Score = 40.0 bits (92), Expect = 0.014
Identities = 70/351 (19%), Positives = 118/351 (33%), Gaps = 74/351 (21%)
Query: 17 RSVEVAAGSPAVFEAETERAGVKVRWQRGGSDIS--ASNKYGLATEGTRHTLTVREVGPA 74
+ V+V AV E E V W + G +I+ ++ E H + + E +
Sbjct: 3154 KEVQVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQS 3213
Query: 75 DQGSYAVIAGSSKVKFDLKVIEAE------KAEPMLAPAPAPAEATGAPGEAPAPAAE-- 126
D G Y +AG ++ L V E + +P+ + PA P P
Sbjct: 3214 DAGEYTFVAGRNRSSVTLYVNAPEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWY 3273
Query: 127 ------------------------LGESAPSPKG---------------SSSAALNGPTP 147
L E+ P S+S ++ P
Sbjct: 3274 KEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEV 3333
Query: 148 GAPDDPIGLF---VMRP-QDGEVTVGGSITFSARVAGASLLKPPVVKWFKGKWVDLSSKV 203
+PD + ++ ++ P QD + G F RV+G L V W+ S+
Sbjct: 3334 VSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDL----KVSWYSKDKKIKPSRF 3389
Query: 204 GQHLQLHDSYDRASKVYLFELHITDAQPAFTGSYRCEVSTKDKFDCSNFNLT-------V 256
+ Q D+Y +L I +A P G+Y S S NL+ +
Sbjct: 3390 FRMTQFEDTY---------QLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESIL 3440
Query: 257 HEAMGTG-DLDLLSAFRRTSLAGGGRRISDSHEDTGILDFSSLLKKRDSFR 306
HE + ++++ F R D+ D+ +D S+ KR + R
Sbjct: 3441 HERIEQEIEMEMKELFSEGESEHSERDTRDAFSDSEDIDHKSMAAKRYASR 3491
Score = 39.7 bits (91), Expect = 0.019
Identities = 46/199 (23%), Positives = 87/199 (43%), Gaps = 20/199 (10%)
Query: 453 PVLITRPLEDQLVMVGQRVEFECEV-SEEGAQVKWLKDGVELTREETFKYRFKKDGQRHH 511
PV + +P+ + + GQ F+ +V + W DG ++ + T K K+DG +
Sbjct: 1457 PVFVLKPVSFKC-LEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQ-S 1514
Query: 512 LIINEAMLEDAGHYALCT---SGGQALAELI-VQEKKLEVYQSIADLM--VGAKDQAVFK 565
LII A D+G + + +G +++ ++ V+ + +V + + V K+ + +
Sbjct: 1515 LIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLE 1574
Query: 566 CEV---SDENVRGVWLKNGKELVPDS--RIKVSHIGRVHKLTIDDVTPADEADYSFVPEG 620
+V + N VWLKN +VP +I++ L ID D A Y+
Sbjct: 1575 MKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAIN 1634
Query: 621 FA------CNLSAKLHFME 633
A C ++ ++ F E
Sbjct: 1635 KAGRDTTRCKVNVEVEFAE 1653
Score = 39.3 bits (90), Expect = 0.024
Identities = 29/94 (30%), Positives = 37/94 (39%), Gaps = 1/94 (1%)
Query: 11 AFSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVRE 70
A SK VA AVFE E K W R G + +N ++G + L +
Sbjct: 2621 AISKPLTDQTVAESQEAVFECEVANPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAA 2680
Query: 71 VGPADQGSYAVIAGSSKVKFDLKVIEAEKAEPML 104
D G Y +SK LKV EA K + L
Sbjct: 2681 TKLDDIGEYTYKVATSKTSAKLKV-EAVKIKKTL 2713
Score = 39.3 bits (90), Expect = 0.024
Identities = 22/88 (25%), Positives = 41/88 (46%), Gaps = 16/88 (18%)
Query: 29 FEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYAVIAGSS-- 86
FE G+ +W + G +I +++K + T+ H+L +R V D Y +AG +
Sbjct: 2988 FEVTVNYEGISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKATS 3047
Query: 87 ---------KVKF-----DLKVIEAEKA 100
++F D+KV+E ++A
Sbjct: 3048 TATLYVEARHIEFRKHIKDIKVLEKKRA 3075
Score = 38.9 bits (89), Expect = 0.032
Identities = 45/189 (23%), Positives = 61/189 (32%), Gaps = 46/189 (24%)
Query: 393 EVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQC----VVGGEKC----- 443
EVKW K I+ KY+ TL I L+D A Y+C VG C
Sbjct: 5410 EVKWYKEYMCIEPDNIKYVISEEKGSHTLKIRNVCLSDSATYRCRAVNCVGEAICRGFLT 5469
Query: 444 --STELF--------------------------------VKEPPVLITRPLEDQLVMVGQ 469
+E+F V E P + + D +G
Sbjct: 5470 MGDSEIFAVIAKKSKVTLSSLMEELVLKSNYTDSFFEFQVVEGPPRFIKGISDCYAPIGT 5529
Query: 470 RVEFECEV-SEEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALC 528
F+C V V W KDG +L + F G H+L I + D G Y
Sbjct: 5530 AAYFQCLVRGSPRPTVYWYKDG-KLVQGRRFTVEESGTG-FHNLFITSLVKSDEGEYRCV 5587
Query: 529 TSGGQALAE 537
+ +AE
Sbjct: 5588 ATNKSGMAE 5596
Score = 37.7 bits (86), Expect = 0.071
Identities = 30/109 (27%), Positives = 43/109 (39%), Gaps = 1/109 (0%)
Query: 1163 PGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLG 1222
PG E + L+ P F V+ + G TA V G P P+ WF +G +
Sbjct: 1439 PGRRLEETDESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIV 1498
Query: 1223 EDARFRMFSKQ-GVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
D ++ K+ G +L I P D G + A N G + L V
Sbjct: 1499 NDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTV 1547
Score = 36.2 bits (82), Expect = 0.21
Identities = 20/79 (25%), Positives = 34/79 (43%), Gaps = 1/79 (1%)
Query: 17 RSVEVAAGSPAVFEAETERAGV-KVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPAD 75
+ V V G+ AV E + V V+W I ++ +GT+ L + +D
Sbjct: 2452 KDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHASD 2511
Query: 76 QGSYAVIAGSSKVKFDLKV 94
+G Y +I G + +L V
Sbjct: 2512 EGPYKLIVGRVETNCNLSV 2530
Score = 35.8 bits (81), Expect = 0.27
Identities = 19/72 (26%), Positives = 35/72 (48%), Gaps = 1/72 (1%)
Query: 14 KKPRSVEVAAGSPAVFEAETERAGVK-VRWQRGGSDISASNKYGLATEGTRHTLTVREVG 72
K +++ V AVF E VK V+W + G + ++ KY ++ +GT ++L ++
Sbjct: 2711 KTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYSLRIKNCA 2770
Query: 73 PADQGSYAVIAG 84
D+ Y G
Sbjct: 2771 IVDESVYGFRLG 2782
Score = 35.4 bits (80), Expect = 0.35
Identities = 16/47 (34%), Positives = 30/47 (63%)
Query: 40 VRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYAVIAGSS 86
V++ R G++I +S + ++ EG ++L + E P D G+Y+V A +S
Sbjct: 135 VKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNS 181
Score = 35.4 bits (80), Expect = 0.35
Identities = 22/90 (24%), Positives = 39/90 (43%), Gaps = 3/90 (3%)
Query: 451 EPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQV-KWLKDGVELTREETFKYRFKKDGQR 509
EPP ++ + G + EC +S E V W ++GV L + + K++F++
Sbjct: 4156 EPPKMLQEMPKHARCREGDSIILECLISGEPQPVVTWFQNGVLLKQNQ--KFQFEEVNCS 4213
Query: 510 HHLIINEAMLEDAGHYALCTSGGQALAELI 539
H L I + +D+G Y E +
Sbjct: 4214 HQLYIKDVNSQDSGKYKCVAENNSGAVESV 4243
Score = 34.7 bits (78), Expect = 0.60
Identities = 27/92 (29%), Positives = 40/92 (43%), Gaps = 12/92 (13%)
Query: 564 FKCEVSDENVRGV-WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFA 622
F EV V GV W +N L PD RIK+ +G V L I ++ + +Y A
Sbjct: 5202 FIVEVEGLPVPGVKWYRNKSLLEPDERIKMERVGNVCSLEISNIQKGEGGEYMC----HA 5257
Query: 623 CNLSAKLHFMEVKIDFVPRQE------PPKIH 648
N+ + +D +P++E PP H
Sbjct: 5258 VNIIGEAKSF-ANVDIMPQEERVVALPPPVTH 5288
Score = 34.3 bits (77), Expect = 0.78
Identities = 20/85 (23%), Positives = 36/85 (42%), Gaps = 9/85 (10%)
Query: 5 GKKPVSAFSKKPRSVEVAAG--SPAVFEAETERAGVKVR-------WQRGGSDISASNKY 55
GKK KPR + + G V E + + VKV W + G ++ S++
Sbjct: 2342 GKKTTCKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRV 2401
Query: 56 GLATEGTRHTLTVREVGPADQGSYA 80
+ + H L + ++ D G+Y+
Sbjct: 2402 HIVIDKQSHMLLIEDMTKEDAGNYS 2426
Score = 32.7 bits (73), Expect = 2.3
Identities = 21/72 (29%), Positives = 35/72 (48%), Gaps = 2/72 (2%)
Query: 460 LEDQLVMVGQRVEFECEVSEEGA-QVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAM 518
+++ ++ G V F C++S ++ W KDG + E ++ F +DG R L I +
Sbjct: 1297 IKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDG-RASLRIPVVL 1355
Query: 519 LEDAGHYALCTS 530
ED G Y S
Sbjct: 1356 PEDEGIYTAFAS 1367
Score = 31.6 bits (70), Expect = 5.1
Identities = 18/61 (29%), Positives = 27/61 (44%), Gaps = 1/61 (1%)
Query: 560 DQAVFKCEVSDENVRGV-WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVP 618
D + +C +S E V W +NG L + + + + H+L I DV D Y V
Sbjct: 4174 DSIILECLISGEPQPVVTWFQNGVLLKQNQKFQFEEVNCSHQLYIKDVNSQDSGKYKCVA 4233
Query: 619 E 619
E
Sbjct: 4234 E 4234
Score = 30.8 bits (68), Expect = 8.6
Identities = 22/97 (22%), Positives = 44/97 (45%), Gaps = 3/97 (3%)
Query: 981 QTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLA-GEEVSIRNSPTDTILFIRAARRVH 1039
Q + + G+P G+P+P+++W KE Q L+ G + + + L + A
Sbjct: 3246 QPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPED 3305
Query: 1040 SGTYQVTVRIEN--MEDKATLVLQVVDKPSPPQDLRV 1074
+ Y + + A+L ++V + SP Q++ V
Sbjct: 3306 AAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPV 3342
>gi|140560919 myomesin 1 isoform a [Homo sapiens]
Length = 1685
Score = 115 bits (289), Expect = 2e-25
Identities = 85/279 (30%), Positives = 120/279 (43%), Gaps = 39/279 (13%)
Query: 732 DRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVID----VPDAPAAP---KISNVG 784
+R+ T KEDEG+YT+ V+ +Q + V V D + APAAP K
Sbjct: 463 ERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEAN 522
Query: 785 EDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEM 844
+D + W+ PA DGG PILGY +++ + + W + N ++ +IEG Y
Sbjct: 523 KDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIF 582
Query: 845 RVYAVNAIGMSRPSPASQPFMPIGP------------------------------PSEPT 874
RV AVN +G+ PS S+P + P P PT
Sbjct: 583 RVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPT 642
Query: 875 HLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGL-TEHTSILVKD 933
L+V + + + V L W+PP + G G+ Y VE C G W L + + D
Sbjct: 643 DLSVTEATRSYVVLSWKPPGQRGHEGI-MYFVEKCEAGTENWQRVNTELPVKSPRFALFD 701
Query: 934 LPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPR 972
L G FRVR N AG G P TE V + L P+
Sbjct: 702 LAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPK 740
Score = 82.0 bits (201), Expect = 3e-15
Identities = 53/189 (28%), Positives = 84/189 (44%), Gaps = 9/189 (4%)
Query: 786 DSCTVQWEPPAYDGGQPILGYILERKKKKSY---RWMRLNFDLIQELSHEARRMIEGVVY 842
DS + W+ P GG I GY + ++ +W N + E +++ + E +VY
Sbjct: 948 DSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVY 1007
Query: 843 EMRVYAVNAIGMSRPSPASQPF----MPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGA 898
+ +V A+N G+ PS S+ F I P P L +V ++ L+W+PP G
Sbjct: 1008 QFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGR 1067
Query: 899 GGLDGYSVEYCPEGCSE--WVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPV 956
+ GY V+ E W + ++ + V+ L G +FRVRA N AG G P
Sbjct: 1068 TPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPS 1127
Query: 957 TTTEPVTVQ 965
PV +
Sbjct: 1128 DLAGPVVAE 1136
Score = 74.7 bits (182), Expect = 5e-13
Identities = 86/401 (21%), Positives = 157/401 (39%), Gaps = 26/401 (6%)
Query: 771 VPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDL-IQEL 829
VP P ++ + W+PP G + I+ Y +E+ + + W R+N +L ++
Sbjct: 637 VPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSP 695
Query: 830 SHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PIGPPSEPTHLAVEDVSDTTV 886
+ EG Y RV N+ G+ PS A++ + + P P + +DT+V
Sbjct: 696 RFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSV 755
Query: 887 SLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRA 946
+ W E A L GY +E G +W + + L TG +FRVRA
Sbjct: 756 VVSWE--ESKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRA 813
Query: 947 HNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVT 1006
N AG +E + V + + + + + + L +G+
Sbjct: 814 VNAAGLSEYSQDSEAIEV-------KAAIGGGVSPDVCPALSDEPGGLTASRGRVHEASP 866
Query: 1007 WTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTV------RIENMEDKATLVL 1060
T + L G + + + P+ + + S T Q + + K+ +
Sbjct: 867 PTFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLK 926
Query: 1061 QVVDK--PSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTV---QKADKKTMEWFTV 1115
+ D+ PSPP D+ +++ ++ L WK P +G E+ GY V + D +W
Sbjct: 927 KKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREA 986
Query: 1116 -LEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTK 1155
++ + L Y F+V + NM G +A ++
Sbjct: 987 NVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSE 1027
Score = 72.8 bits (177), Expect = 2e-12
Identities = 70/293 (23%), Positives = 101/293 (34%), Gaps = 71/293 (24%)
Query: 868 GPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHT 927
G P+ P + + + + + W+ P G + GY ++ C G W +
Sbjct: 508 GAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFA 567
Query: 928 SILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKV 987
V L G +FRVRA N G G P +EPV + ++ RL
Sbjct: 568 RFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARL-------------- 613
Query: 988 GEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTV 1047
K RP WT GQ + EE P++ I+
Sbjct: 614 ------------KSRPSAPWT--GQIIVTEE-----EPSEGIV----------------- 637
Query: 1048 RIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADK 1107
P PP DL VT+A V L WKPP G+ + Y V+K +
Sbjct: 638 ------------------PGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEA 678
Query: 1108 KTMEWFTVLEH--YRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPV 1158
T W V + + +L G Y FRV N G + + T+ V
Sbjct: 679 GTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTV 731
Score = 70.1 bits (170), Expect = 1e-11
Identities = 43/120 (35%), Positives = 62/120 (51%), Gaps = 4/120 (3%)
Query: 769 IDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERK--KKKSYRWMRLNFDLI 826
I VP P + K S V +DS +QW+PP + G P+ GY ++ K K K +W LN I
Sbjct: 1036 IAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAI 1095
Query: 827 QELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTV 886
+ + + R + EGV Y RV A+N G+ +PS + P + P T V +V D V
Sbjct: 1096 KNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPG--TKEVVVNVDDDGV 1153
Score = 57.8 bits (138), Expect = 7e-08
Identities = 77/336 (22%), Positives = 131/336 (38%), Gaps = 69/336 (20%)
Query: 471 VEFECEVS--EEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALC 528
V +C+V+ ++ + W KD E++ +E + KDG L+I E +DAG Y +
Sbjct: 1374 VLLKCKVANIKKETHIVWYKDEREISVDEKHDF---KDGICT-LLITEFSKKDAGIYEVI 1429
Query: 529 TSGGQA-------LAELIVQEKKLEVYQSIA----DLMVGAKDQAVFKCEVSD---ENVR 574
+ L + +E +EV + IA DL + + + + E+++
Sbjct: 1430 LKDDRGKDKSRLKLVDEAFKELMMEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVEDLK 1489
Query: 575 GVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGF--------ACNLS 626
W NG + R+K G L I++ TP D+ Y V E F +LS
Sbjct: 1490 VNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKY--VMELFDGKTGHQKTVDLS 1547
Query: 627 AKLH------FMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPT 680
+ + F +K + + ++ G +PD + + G L L + GDP P
Sbjct: 1548 GQAYDEAYAEFQRLKQAAIAEKNRARVL----GGLPDVVTIQEGKALNLTCNVWGDPPPE 1603
Query: 681 VIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEG 740
V W K +K L + ++ E + + FT+ G
Sbjct: 1604 VSWLKN---------------------------EKALASDDHCNLKFEAGRT-AYFTING 1635
Query: 741 AEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPA 776
D G Y + VKN G + + TV V +P+ A
Sbjct: 1636 VSTADSGKYGLVVKNKYGSETSDFTVSVF-IPEEEA 1670
Score = 51.6 bits (122), Expect = 5e-06
Identities = 50/200 (25%), Positives = 79/200 (39%), Gaps = 22/200 (11%)
Query: 1066 PSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTV--QKADKKTMEWFTVLE-HYRRT 1122
P PP L+ ++ ++ L+WKPP G T + GY V ++A K +W + E +
Sbjct: 1039 PGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNV 1098
Query: 1123 HCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPS 1182
+ V L G Y FRV + N G + V RPG
Sbjct: 1099 YLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPG------------------ 1140
Query: 1183 FTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRK 1242
T+ +V G ++ + +PK + SW K+ + + R + SK + +
Sbjct: 1141 -TKEVVVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKD 1199
Query: 1243 PCPFDGGIYVCRATNLQGEA 1262
D GIY C T+ G A
Sbjct: 1200 LGMDDLGIYSCDVTDTDGIA 1219
Score = 46.2 bits (108), Expect = 2e-04
Identities = 42/168 (25%), Positives = 70/168 (41%), Gaps = 14/168 (8%)
Query: 1002 RPQVTWTKEGQPLAGEE-VSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVL 1060
+P++ W + G PL+ + V S L + G Y + VR+ ++ + +
Sbjct: 438 QPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYV 497
Query: 1061 QVVDK-------PSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWF 1113
V D P+ P D++ +A + + WK P G + + GY + K + T W
Sbjct: 498 FVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWS 557
Query: 1114 TVLE-HYRRTHCVVPELIIGNGYYFRVFSQNM--VGFSDRAATTKEPV 1158
+ + V LI G Y FRV + N +GF R + EPV
Sbjct: 558 QCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVS---EPV 602
Score = 45.8 bits (107), Expect = 3e-04
Identities = 101/539 (18%), Positives = 183/539 (33%), Gaps = 83/539 (15%)
Query: 391 DAEVKWLKNGQEIQMSGS--KYIFESIGAKRTLTISQCSLADDAAYQC----VVGGEKCS 444
+ V W KN I + + KYI ES TL I+ C D A Y+ V G
Sbjct: 305 EPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRASAMNVKGELSAY 364
Query: 445 TELFVKE----------PPVLITRPL---------------------------EDQLVMV 467
+ VK T PL E + + +
Sbjct: 365 ASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIHFDDKFDVSFGREGETMSL 424
Query: 468 GQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYAL 527
G RV E+ +++W ++GV L+ + + + G+R L + ED G Y +
Sbjct: 425 GCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWS--GERATLTFSHLNKEDEGLYTI 482
Query: 528 CTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPD 587
G+ ++ V+ AD + A + + N + + + V
Sbjct: 483 RVRMGE-----YYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDG 537
Query: 588 SRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKI 647
+ + ++ D + ++ F + + + V+ K+
Sbjct: 538 GSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRA-------VNKM 590
Query: 648 HLDCPGRIPDTIVVV-----AGNKLRLDVPISG-------DPAPTVI----WQKAITQGN 691
+ P R+ + + + A K R P +G +P+ ++ ++T+
Sbjct: 591 GIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEAT 650
Query: 692 KAPARPAPDAPEDTGDSDEWVFDKKLLCETEG--RVRVETTKDRSIFTVEGAEKEDEGVY 749
++ + P G F +K TE RV E F + + +
Sbjct: 651 RSYVVLSWKPPGQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCF 710
Query: 750 TVTVKNPVGEDQVNLTVKV------IDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPI 803
V N G + + +V +D+P AP S + S V WE + +
Sbjct: 711 RVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEESK--DAKEL 768
Query: 804 LGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQ 862
+GY +E S +W N + ++ ++ G Y RV AVNA G+S S S+
Sbjct: 769 VGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSE 827
Score = 43.1 bits (100), Expect = 0.002
Identities = 28/101 (27%), Positives = 45/101 (44%), Gaps = 3/101 (2%)
Query: 869 PPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEY--CPEGC-SEWVAALQGLTE 925
PPS P + + ++ L W+ P+++G + GY V Y +G +W A
Sbjct: 933 PPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVS 992
Query: 926 HTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQE 966
+ + +L F+V A NMAG GAP +E +E
Sbjct: 993 EEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEE 1033
Score = 40.4 bits (93), Expect = 0.011
Identities = 27/86 (31%), Positives = 45/86 (52%), Gaps = 5/86 (5%)
Query: 1180 APSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDA---RFRMFSKQGVL 1236
AP F + +V L C++ G P+P+++W+KN + + A ++ + S+ G+
Sbjct: 276 APEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMH 335
Query: 1237 TLEIRKPCPF-DGGIYVCRATNLQGE 1261
TLEI C F D Y A N++GE
Sbjct: 336 TLEI-NGCDFEDTAQYRASAMNVKGE 360
Score = 33.5 bits (75), Expect = 1.3
Identities = 22/78 (28%), Positives = 41/78 (52%), Gaps = 6/78 (7%)
Query: 358 DEKKSTAFQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFES-IG 416
D+K +F ++ E +S G ++ +T E+ E++W +NG + +S SK++ G
Sbjct: 408 DDKFDVSFGREGET---MSLGCRVVITPEIKHFQPEIQWYRNG--VPLSPSKWVQTLWSG 462
Query: 417 AKRTLTISQCSLADDAAY 434
+ TLT S + D+ Y
Sbjct: 463 ERATLTFSHLNKEDEGLY 480
Score = 32.0 bits (71), Expect = 3.9
Identities = 22/81 (27%), Positives = 29/81 (35%), Gaps = 1/81 (1%)
Query: 1195 GYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRM-FSKQGVLTLEIRKPCPFDGGIYVC 1253
G L C V G P P++SW KN L D + F I D G Y
Sbjct: 1587 GKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGL 1646
Query: 1254 RATNLQGEARCECRLEVRVPQ 1274
N G + + V +P+
Sbjct: 1647 VVKNKYGSETSDFTVSVFIPE 1667
Score = 31.6 bits (70), Expect = 5.1
Identities = 27/120 (22%), Positives = 44/120 (36%), Gaps = 24/120 (20%)
Query: 21 VAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYA 80
++ G V E + +++W R G +S S G R TLT + D+G Y
Sbjct: 422 MSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYT 481
Query: 81 V-----------------------IAGSSKVKFDLKVIEAEKAEPMLAPAPAPAEATGAP 117
+ I G+ D+K +EA K + ++ PA G+P
Sbjct: 482 IRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANK-DYIIISWKQPAVDGGSP 540
Score = 31.2 bits (69), Expect = 6.6
Identities = 25/90 (27%), Positives = 34/90 (37%), Gaps = 1/90 (1%)
Query: 350 KRLKGMRRDEKKSTAFQKKLEPAYQVSKGHKIRLTVEL-ADHDAEVKWLKNGQEIQMSGS 408
+RLK EK L + +G + LT + D EV WLKN + +
Sbjct: 1559 QRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDH 1618
Query: 409 KYIFESIGAKRTLTISQCSLADDAAYQCVV 438
+ G TI+ S AD Y VV
Sbjct: 1619 CNLKFEAGRTAYFTINGVSTADSGKYGLVV 1648
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 111 bits (278), Expect = 4e-24
Identities = 205/938 (21%), Positives = 347/938 (36%), Gaps = 161/938 (17%)
Query: 381 IRLTVELADHDA-EVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVV- 438
I LT E++ ++ WLKN Q I+++ + I + RTL I + ++D Y C+
Sbjct: 2982 ISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLI---VPGGRTLQIIRAKVSDGGEYTCIAI 3038
Query: 439 ---GGEKCSTELFVKEPPVLITRPLEDQLVM---VGQRVEFECEVSEEGAQV-KWLKDGV 491
G K L V PP + E V+ G V ECE + V W K+G
Sbjct: 3039 NQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKNGR 3098
Query: 492 ELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSI 551
+T E+ DGQ H I +A + D G Y +A+ +K + +
Sbjct: 3099 MIT--ESTHVEILADGQMLH--IKKAEVSDTGQYVC-----RAINVAGRDDKNFHLNVYV 3149
Query: 552 ADLMVGAKDQAVFK---------CEVSDENVRGV-WLKNGKELVPDSRIKVSHIGRVHKL 601
+ G + + + + C+ + + WLKN K + ++V + KL
Sbjct: 3150 PPSIEGPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKL 3209
Query: 602 TIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVV 661
I +D +Y+ + A N+ K K F+ Q PP + IP + V
Sbjct: 3210 QIARSQHSDSGNYTCI----ASNMEGKAQ----KYYFLSIQVPPSV---AGAEIPSDVSV 3258
Query: 662 VAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCET 721
+ G + L +G P P + W K P +G+++
Sbjct: 3259 LLGENVELVCNANGIPTPLIQWLK-------------DGKPIASGETE------------ 3293
Query: 722 EGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVP----DAPAA 777
R+ + + S + GA D G YT NP GE+ + V P + A
Sbjct: 3294 ----RIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEA 3349
Query: 778 PKISNVGEDS----CTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEA 833
K+ + + S C PP P + ++ K+ + L+ + + +
Sbjct: 3350 EKLMTLVDTSINIECRATGTPP------PQINWL------KNGLPLPLSSHIRLLAAGQV 3397
Query: 834 RRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPP 893
R++ V ++ VY A + PP+ + E+++ LK
Sbjct: 3398 IRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEIT----VLK---- 3449
Query: 894 ERVGAGGLDGYSVEYCPEGCSEWVAALQ--GLTEHTSILVKDLPTGARLLFRVRAHNM-A 950
G+ + P W+ Q GL H ++ T +L ++A +
Sbjct: 3450 ---GSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTV-----STHGMVLQLLKAETEDS 3501
Query: 951 GPGAPVTTTEPVTVQE-----ILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQV 1005
G + + E V + +L+ P + + I V P+ L G P P++
Sbjct: 3502 GKYTCIASNEAGEVSKHFILKVLEPPHINGSEE-HEEISVIVNNPLELTCIASGIPAPKM 3560
Query: 1006 TWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDK 1065
TW K+G+PL + ++ +L I A+ +G Y +D +++V
Sbjct: 3561 TWMKDGRPLPQTD-QVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRV--- 3616
Query: 1066 PSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQ-KADKKTMEWFTVLEHYRRTHC 1124
P ++ TD P+D+ T++ K+D T L + R
Sbjct: 3617 -HVPPNIAGTD-----------EPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQA 3664
Query: 1125 VVPELIIGNGYYFRVFSQNM--------VGFSDRAATTKEPVFIPRPGITYEPPNYKALD 1176
I+ G Y ++ + ++ V + TT+E FI + PPN K
Sbjct: 3665 TPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTRE--FILTVNV---PPNIKG-- 3717
Query: 1177 FSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDL-GEDARFRMFSKQGV 1235
P L+N+S + L C G P P+I+W K+G L G AR+ +
Sbjct: 3718 ---GPQSLVILLNKSTV------LECIAEGVPTPRITWRKDGAVLAGNHARYSILENG-- 3766
Query: 1236 LTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVRVP 1273
L I+ D G Y+C ATN G R L+V VP
Sbjct: 3767 -FLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVP 3803
Score = 83.2 bits (204), Expect = 1e-15
Identities = 201/933 (21%), Positives = 341/933 (36%), Gaps = 161/933 (17%)
Query: 392 AEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVV----GGEKCSTEL 447
A + W K+GQ ++ I + TL I + ++D Y CV G ++ ++
Sbjct: 2704 ASLSWYKDGQPLKSDDHVNIAAN---GHTLQIKEAQISDTGRYTCVASNIAGEDELDFDV 2760
Query: 448 FVKEPP----------VLIT-RPLEDQLVMVGQRVEFECEVSEEGAQ-VKWLKDGVELTR 495
++ PP +L T R E + V++ + CE + + W KDG LT
Sbjct: 2761 NIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGHPLTS 2820
Query: 496 EETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIA--- 552
+ K G+ L I A +EDAG Y C + +A + + + ++ V I
Sbjct: 2821 SD--KVLILPGGRV--LQIPRAKVEDAGRYT-CVAVNEAGEDSLQYDVRVLVPPIIKGAN 2875
Query: 553 -----DLMVGAKDQAVFKCEVSDENV-RGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDV 606
++ V A+ +C S R W K+G+ L+ D K GR+ ++ +
Sbjct: 2876 SDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQI 2935
Query: 607 TPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNK 666
T D Y V E A SAK +F + + P PK + + VV N
Sbjct: 2936 T--DIGRYVCVAENTAG--SAKKYF-NLNVHVPPSVIGPK---------SENLTVVVNNF 2981
Query: 667 LRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVR 726
+ L +SG P P + W K N+ P + + L GR
Sbjct: 2982 ISLTCEVSGFPPPDLSWLK-----NEQPIK----------------LNTNTLIVPGGRT- 3019
Query: 727 VETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDA----PAAPKISN 782
+ A+ D G YT N GE + ++ V P + + N
Sbjct: 3020 ---------LQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVN 3070
Query: 783 VGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVY 842
V E + +V E + P++ + + + + D Q L + + + Y
Sbjct: 3071 VREGT-SVSLECESNAVPPPVITWYKNGRMITESTHVEILAD-GQMLHIKKAEVSDTGQY 3128
Query: 843 EMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSD---TTVSLKWRPPERVGAG 899
R A+N G + ++P + VE +S+ T PP +
Sbjct: 3129 VCR--AINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTCDATGIPPPTIA-- 3184
Query: 900 GLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTT 959
W+ + + S+ V+ L G++L H+ +G + +
Sbjct: 3185 ----------------WLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASN 3228
Query: 960 EPVTVQEI----LQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLA 1015
Q+ +Q P + + +GE V L+ G P P + W K+G+P+A
Sbjct: 3229 MEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIA 3288
Query: 1016 -GEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRV 1074
GE IR S + L I A +G Y V P+ +D
Sbjct: 3289 SGETERIRVSANGSTLNIYGALTSDTGKYTC----------------VATNPAGEED--- 3329
Query: 1075 TDAWGLNVALEWKPPQDVGNTELWGYTVQKADK-KTMEWFTVLEHYRRTHCVVPEL-IIG 1132
+ LNV + P GN + +A+K T+ ++ R T P++ +
Sbjct: 3330 -RIFNLNV---YVTPTIRGNKD-------EAEKLMTLVDTSINIECRATGTPPPQINWLK 3378
Query: 1133 NGY------YFRVFSQNMVGFSDRAATTKEPVFI----PRPGITYEPPNYKALDFSEAPS 1182
NG + R+ + V RA + V+ R G+ + N L P+
Sbjct: 3379 NGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYN---LQVFAPPN 3435
Query: 1183 FTQPLVNRSV--IAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEI 1240
+ + + G + + C G+P P ++W ++G LG DA + S G + L++
Sbjct: 3436 MDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTV-STHG-MVLQL 3493
Query: 1241 RKPCPFDGGIYVCRATNLQGEARCECRLEVRVP 1273
K D G Y C A+N GE L+V P
Sbjct: 3494 LKAETEDSGKYTCIASNEAGEVSKHFILKVLEP 3526
Score = 80.1 bits (196), Expect = 1e-14
Identities = 194/922 (21%), Positives = 323/922 (35%), Gaps = 151/922 (16%)
Query: 393 EVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCV---VGGEKCSTELFV 449
E +W+KN + + YI ++ + +L I + L D Y CV V G T V
Sbjct: 921 ERRWIKNSAMLLQN--PYI--TVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVV 976
Query: 450 KEPPVLITRPLEDQLVMVGQRVEFECEVS-EEGAQVKWLKDGVELTREETFKYRFKKDGQ 508
I + + G V C+ S V W K G EL + K+ DG
Sbjct: 977 VHVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKG-ELISTSSAKFSAGADGS 1035
Query: 509 RHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVY--------------QSIADL 554
L + E++G Y + A+ VQ L VY ++
Sbjct: 1036 ---LYVVSPGGEESGEYVCTATNTAGYAKRKVQ---LTVYVRPRVFGDQRGLSQDKPVEI 1089
Query: 555 MVGAKDQAVFKCEVSDENVRGV-WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEAD 613
V A ++ CEV + W K + + P S K+T + +D
Sbjct: 1090 SVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKIT--ETRTSDSGM 1147
Query: 614 YSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPI 673
Y V A N++ VK++ PPKI R P + V G ++ +
Sbjct: 1148 YLCVATNIAGNVT-----QAVKLNV---HVPPKIQ-----RGPKHLKVQVGQRVDIPCNA 1194
Query: 674 SGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDR 733
G P P + W K G S V + + +G +
Sbjct: 1195 QGTPLPVITWSK--------------------GGSTMLVDGEHHVSNPDGTL-------- 1226
Query: 734 SIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAP--AAPKISNVGEDSCTVQ 791
+++ A D G+YT N G D+ +T+ V + P P + E +
Sbjct: 1227 ---SIDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVANQR 1283
Query: 792 WEPPAYDGGQPILGYILERKKKKSYRWMRLNFDL------IQELSHEARRMIEGVV-YEM 844
E P G P K + +W+ +L I L +I V Y+
Sbjct: 1284 IEFPCPAKGTP----------KPTIKWLHNGRELTGREPGISILEDGTLLVIASVTPYDN 1333
Query: 845 RVY---AVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGL 901
Y AVN G + + +P P E V++ +V L
Sbjct: 1334 GEYICVAVNEAGTTERKYNLKVHVP------PVIKDKEQVTNVSVLLNQLTNLFC----- 1382
Query: 902 DGYSVEYCPEGCSEWVAALQGLTEHTSI----------LVKDLPTGARLLFRVRAHNMAG 951
VE P W +TE ++I L + P A + +A N+AG
Sbjct: 1383 ---EVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATPEDAGR-YSCKAINIAG 1438
Query: 952 PGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEG 1011
T++ ++L P + + + + + V L +G P P + W K+G
Sbjct: 1439 ------TSQKYFNIDVLVPPTI-IGTNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDG 1491
Query: 1012 QPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQD 1071
+PL + ++ +L ++ ARR G YQ TV + + L + PS
Sbjct: 1492 KPLFLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGG 1551
Query: 1072 LRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELII 1131
TD L +L K + + T K + M L + + +P +
Sbjct: 1552 NVTTDISVLINSLI-KLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQV 1610
Query: 1132 GNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRS 1191
+ + N+ G ++++ Y PP + + PL N+
Sbjct: 1611 SDSATYTCHVANVAGTAEKSFHVD----------VYVPPMIEG-------NLATPL-NKQ 1652
Query: 1192 VIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIY 1251
V+ ++ L C G+P P ++W K+G+ + + R+ + G LEI D G Y
Sbjct: 1653 VVIAHSLTLECKAAGNPSPILTWLKDGVPVKANDNIRI--EAGGKKLEIMSAQEIDRGQY 1710
Query: 1252 VCRATNLQGEARCECRLEVRVP 1273
+C AT++ GE + ++V VP
Sbjct: 1711 ICVATSVAGEKEIKYEVDVLVP 1732
Score = 70.1 bits (170), Expect = 1e-11
Identities = 199/929 (21%), Positives = 322/929 (34%), Gaps = 153/929 (16%)
Query: 396 WLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQC----VVGGEKCSTELFVKE 451
WLK+G + I E+ + L I + D Y C V G + + + +
Sbjct: 2137 WLKDGHPLLKKPGLSISEN---RSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWV 2193
Query: 452 PPVLITRPLEDQLVMV-GQRVEFECEVSE-EGAQVKWLKDGVELTREETFKYRFKKDGQR 509
PP + QL ++ G + CE S + W K G + + + R G++
Sbjct: 2194 PPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQ 2253
Query: 510 HHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVY---------QSIADLMVGAKD 560
+ I E DA Y+ S A+ +E L+VY +++V
Sbjct: 2254 LQISIAEK--SDAALYSCVASNVAGTAK---KEYNLQVYIRPTITNSGSHPTEIIVTRGK 2308
Query: 561 QAVFKCEVSDENVRGV-WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPE 619
+CEV V W+K+G L+ +++ G H L + ++ +D Y V
Sbjct: 2309 SISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEG--HILQLKNIHVSDTGRYVCVAV 2366
Query: 620 GFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAP 679
A ++ K + + V PP I + R P+ I VV N + L SG P P
Sbjct: 2367 NVA-GMTDKKYDLSV-------HAPPSIIGN--HRSPENISVVEKNSVSLTCEASGIPLP 2416
Query: 680 TVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVE 739
++ W K D W VR+ + +
Sbjct: 2417 SITWFK-----------------------DGWP------VSLSNSVRI--LSGGRMLRLM 2445
Query: 740 GAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGED-------SCTVQW 792
ED G YT V+N GE++ + V+ P + +V +C V
Sbjct: 2446 QTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTG 2505
Query: 793 EPPA----YDGGQPI----LGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEM 844
P + GQP+ +I+ R++++ + ++
Sbjct: 2506 NPVPEITWHKDGQPLQEDEAHHII-----SGGRFLQITNVQVPHTGRYTCLASSPAGHKS 2560
Query: 845 RVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGY 904
R +++N S +G P D TV L P V + Y
Sbjct: 2561 RSFSLNVF-------VSPTIAGVGSDGNP--------EDVTVILN-SPTSLV----CEAY 2600
Query: 905 SVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTE---- 960
S P W L + +I + LP G L + AG + V T E
Sbjct: 2601 SY---PPATITWFKDGTPLESNRNIRI--LPGGRTLQILNAQEDNAGRYSCVATNEAGEM 2655
Query: 961 ------PVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPL 1014
V + I+ + L P + ++ KV + L P ++W K+GQPL
Sbjct: 2656 IKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPL 2715
Query: 1015 AGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRV 1074
++ + + L I+ A+ +G Y ED+ + + PS + +
Sbjct: 2716 KSDD-HVNIAANGHTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEI 2774
Query: 1075 TDAWGLNVALEWKPPQDVGNTELWGY-TVQKADKKTMEWFTVLEHYRRTHCVVPE---LI 1130
+ L+ + + N + Y A T+ W Y+ H + LI
Sbjct: 2775 GNM--LDTGRNGEAKDVIINNPISLYCETNAAPPPTLTW------YKDGHPLTSSDKVLI 2826
Query: 1131 IGNGYYFRVFSQNMVGFSDRAATTKEPV-FIPRPGITYE-----PPNYKALDFSEAPSFT 1184
+ G RV D T V + Y+ PP K + S+ P
Sbjct: 2827 LPGG---RVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRVLVPPIIKGAN-SDLPEEV 2882
Query: 1185 QPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPC 1244
LVN+S A++ C GSP P+ SW K+G L ED + S + L+I
Sbjct: 2883 TVLVNKS------ALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRI--LQILNTQ 2934
Query: 1245 PFDGGIYVCRATNLQGEARCECRLEVRVP 1273
D G YVC A N G A+ L V VP
Sbjct: 2935 ITDIGRYVCVAENTAGSAKKYFNLNVHVP 2963
Score = 67.8 bits (164), Expect = 6e-11
Identities = 189/910 (20%), Positives = 299/910 (32%), Gaps = 156/910 (17%)
Query: 394 VKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVV----GGEKCSTELFV 449
+ W K+G + + ++Y SI L I + D Y C+ G ++ +L V
Sbjct: 3744 ITWRKDGAVLAGNHARY---SILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQV 3800
Query: 450 KEPPVLITRPLEDQLVMVGQRVEFECEVSE-EGAQVKWLKDGVELTREETFK-YRFKKDG 507
PP + P + V+V + CE + + W K+G L ++ YR G
Sbjct: 3801 HVPPSIAPGPT-NMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSG 3859
Query: 508 QRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIAD----LMVGAKDQAV 563
L+I ++D Y CT A + + ++V SIAD +V AV
Sbjct: 3860 S---LVIISPSVDDTATYE-CTVTNGAGDDKRTVDLTVQVPPSIADEPTDFLVTKHAPAV 3915
Query: 564 FKCEVSDENVRGV-WLKNGKELVP-DSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGF 621
C S + W KNG L+P ++ G + L A + +++
Sbjct: 3916 ITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEIL-------ATQLNHAGRYTCV 3968
Query: 622 ACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTV 681
A N + H V + EPP I P + V+ N + L +G P+P +
Sbjct: 3969 ARNAAGSAH-RHVTLHV---HEPPVIQPQ-----PSELHVILNNPILLPCEATGTPSPFI 4019
Query: 682 IWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGA 741
WQK N T GR + A
Sbjct: 4020 TWQKEGINVN-----------------------------TSGRNHAVLPSGG--LQISRA 4048
Query: 742 EKEDEGVYTVTVKNPVGE--DQVNLTVKVIDVPDAPAAPKISNVGED---SCTVQWEPPA 796
+ED G Y +NP G ++ L V+V V + V + SC PP
Sbjct: 4049 VREDAGTYMCVAQNPAGTALGKIKLNVQVPPVISPHLKEYVIAVDKPITLSCEADGLPPP 4108
Query: 797 ----YDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAI 852
+ G+ I+ I +R ++ S + + G A N
Sbjct: 4109 DITWHKDGRAIVESIRQR--------------VLSSGSLQIAFVQPGDAGHYTCMAANVA 4154
Query: 853 GMSRPSPASQPFMPIGPPSEPTHLAVEDVSDT----------TVSLKWRPPERVGAGGLD 902
G S S +P S H V + S T ++ W+ + A L
Sbjct: 4155 GSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLG 4214
Query: 903 GYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPV 962
Y+ E P G ++++++ + A+N AG T T +
Sbjct: 4215 KYTAE--PYG---------------ELILENVVLEDSGFYTCVANNAAGED---THTVSL 4254
Query: 963 TVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIR 1022
TV L L + GE + L G P P++TWT + S+
Sbjct: 4255 TVHV------LPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFDSVN 4308
Query: 1023 NSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNV 1082
L I + SGTY T KA + V + P D
Sbjct: 4309 GHSE---LVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDY---------- 4355
Query: 1083 ALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQ 1142
W P +G + V+ T++W +H + +GNG +
Sbjct: 4356 PSNWIEP--LGGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQ---LGNGSLAIYGTV 4410
Query: 1143 NMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCC 1202
N T E + R +L P T V + AG +L C
Sbjct: 4411 NEDAGDYTCVATNEAGVVERS---------MSLTLQSPPIITLEPVETVINAGGKIILNC 4461
Query: 1203 AVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEA 1262
G P+P I+W + G + D R + S + + +K D + C A NL G
Sbjct: 4462 QATGEPQPTITWSRQGHSISWDDRVNVLSNNSLYIADAQKE---DTSEFECVARNLMGSV 4518
Query: 1263 RCECRLEVRV 1272
+ V+V
Sbjct: 4519 LVRVPVIVQV 4528
Score = 67.0 bits (162), Expect = 1e-10
Identities = 146/694 (21%), Positives = 257/694 (37%), Gaps = 117/694 (16%)
Query: 394 VKWLKNGQEI-QMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVV----GGEKCSTELF 448
+ WLK+GQ I + G K + R L I+Q +++ Y+C+ G K E+
Sbjct: 1766 IMWLKDGQLIDERDGFKILLNG----RKLVIAQAQVSNTGLYRCMAANTAGDHKKEFEVT 1821
Query: 449 VKEPPVLITRPLEDQLVMVGQRVEFECEVSE-EGAQVKWLKDGVELTREETFKYRFKKDG 507
V PP + + L +++V+ + V +C + + WLKD + T + K
Sbjct: 1822 VHVPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVN---TAQGNLKIQS 1878
Query: 508 QRHHLIINEAMLEDAGHYALCTSGG----QALAELIVQEK-KLEVYQSIADLMVGAKDQA 562
L I + +LEDAG Y + Q +L V E LE + + V +
Sbjct: 1879 SGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKMLNETVLVSNPV 1938
Query: 563 VFKCEVSDENVRGV-WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGF 621
+C+ + V + W K+ + L + + + G++ + I+ +D Y V
Sbjct: 1939 QLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQI--IDIESAQISDAGIYKCVAINS 1996
Query: 622 ACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTV 681
A A F +++ P + + VV N +RL+ G PAP++
Sbjct: 1997 A---GATELFYSLQVHVAPSISGSN----------NMVAVVVNNPVRLECEARGIPAPSL 2043
Query: 682 IWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGA 741
W K G+ + F L + GR I + A
Sbjct: 2044 TWLK---DGSPVSS-----------------FSNGLQVLSGGR----------ILALTSA 2073
Query: 742 EKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPK-----ISNVGEDSCTVQWEPPA 796
+ D G YT N GE Q ++ ++V P+ + IS E C PP
Sbjct: 2074 QISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLCQSDAIPP- 2132
Query: 797 YDGGQPILGYILERKKKKSYRWMRLNFDLIQE--LSHEARRMI----EGVVYEMRVY--- 847
+ W++ L+++ LS R + + V + Y
Sbjct: 2133 -----------------PTLTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCE 2175
Query: 848 AVNAIGMSRPSPASQPFMP--IGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYS 905
A N G + + ++P IG E T L V + +SL + G+ +
Sbjct: 2176 ATNVAGKTEKNYNVNIWVPPNIGGSDELTQLTV--IEGNLISLLCE------SSGIPPPN 2227
Query: 906 VEYCPEG---CSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPV 962
+ + +G ++ + ++ L+ + + L+ A N+AG T +
Sbjct: 2228 LIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAG-----TAKKEY 2282
Query: 963 TVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIR 1022
+Q ++ H + I + G+ ++L QG P P VTW K+G PL + +
Sbjct: 2283 NLQVYIRPTITNSGSHPTEIIVTR-GKSISLECEVQGIPPPTVTWMKDGHPLI-KAKGVE 2340
Query: 1023 NSPTDTILFIRAARRVHSGTYQ-VTVRIENMEDK 1055
IL ++ +G Y V V + M DK
Sbjct: 2341 ILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDK 2374
Score = 65.1 bits (157), Expect = 4e-10
Identities = 147/661 (22%), Positives = 240/661 (36%), Gaps = 139/661 (21%)
Query: 161 PQDGEVTVGGSITFSARVAGASLLKPPVVKWFKGKWVDLSSKVGQHLQLHDSYDRASKVY 220
P + VT G SI+ V G + PP V W K + +K + L D +
Sbjct: 2299 PTEIIVTRGKSISLECEVQG---IPPPTVTWMKDGHPLIKAKGVEIL------DEGHILQ 2349
Query: 221 LFELHITDAQPAFTGSYRCEVSTKDKFDCSNFNLTVHEAMGTGDLDLLSAFRRTSLAGGG 280
L +H++D TG Y C ++L+VH S+ G
Sbjct: 2350 LKNIHVSD-----TGRYVCVAVNVAGMTDKKYDLSVHAP--------------PSIIGNH 2390
Query: 281 RRISDSHEDTGILDFSSLLKKRDSFRTPRDSKLEAPAEEDVWEI--------------LR 326
R S E+ +++ +S+ ++ P S +D W + LR
Sbjct: 2391 R----SPENISVVEKNSVSLTCEASGIPLPS---ITWFKDGWPVSLSNSVRILSGGRMLR 2443
Query: 327 QAPPSEYERIAFQYGVTDLRGMLKRLKGMRRDEKKSTAFQKKLEPAYQVSKGHKIRLTVE 386
+ + + V + G +++ G+ + LE +V + + LT E
Sbjct: 2444 LMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDV-KVKEKQSVTLTCE 2502
Query: 387 LADHDA-EVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVV----GGE 441
+ + E+ W K+GQ +Q + +I I R L I+ + Y C+ G +
Sbjct: 2503 VTGNPVPEITWHKDGQPLQEDEAHHI---ISGGRFLQITNVQVPHTGRYTCLASSPAGHK 2559
Query: 442 KCSTELFVKEPPVLIT-----RPLEDQLVMVGQRVEFECEV-SEEGAQVKWLKDGVELTR 495
S L V P + P ED V++ CE S A + W KDG L
Sbjct: 2560 SRSFSLNVFVSPTIAGVGSDGNP-EDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLES 2618
Query: 496 EETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVY------- 548
+ G R I+N A ++AG Y+ C + +A E+I + +++VY
Sbjct: 2619 NRNIRIL---PGGRTLQILN-AQEDNAGRYS-CVATNEA-GEMI-KHYEVKVYIPPIINK 2671
Query: 549 -------QSIADLMVGAKDQAVFKCEV-SDENVRGVWLKNGKELVPDSRIKVSHIGRVHK 600
S ++ + + +CE + + W K+G+ L D + ++ G H
Sbjct: 2672 GDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANG--HT 2729
Query: 601 LTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDF-VPRQEPPKIH--------LDC 651
L I + +D Y+ V A N++ E ++DF V Q PP LD
Sbjct: 2730 LQIKEAQISDTGRYTCV----ASNIAG-----EDELDFDVNIQVPPSFQKLWEIGNMLDT 2780
Query: 652 PGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEW 711
GR + V+ N + L + P PT+ W K D
Sbjct: 2781 -GRNGEAKDVIINNPISLYCETNAAPPPTLTWYK---------------------DGHPL 2818
Query: 712 VFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDV 771
K+L GRV + A+ ED G YT N GED + V+V+
Sbjct: 2819 TSSDKVLILPGGRV----------LQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRVLVP 2868
Query: 772 P 772
P
Sbjct: 2869 P 2869
Score = 64.3 bits (155), Expect = 7e-10
Identities = 206/992 (20%), Positives = 348/992 (35%), Gaps = 203/992 (20%)
Query: 393 EVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVV----GGEKCSTELF 448
++ W K+G+ + + E + + L + D YQC V G + +L
Sbjct: 1484 DIHWFKDGKPLFLGDPNV--ELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLT 1541
Query: 449 VKEPPVLITRPLEDQL-VMVGQRVEFECEVSE-EGAQVKWLKDGVELTREETFKYRFKKD 506
+ PP + + + V++ ++ ECE + W KDG + Y K
Sbjct: 1542 IYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDK-- 1599
Query: 507 GQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVY---QSIADLMVGAKDQAV 563
GQ H I A + D+ Y + AE + ++VY +L Q V
Sbjct: 1600 GQYLH--IPRAQVSDSATYTCHVANVAGTAE---KSFHVDVYVPPMIEGNLATPLNKQVV 1654
Query: 564 FKCEVSDENVRG-------VWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSF 616
++ E WLK+G + + I++ G+ KL I D Y
Sbjct: 1655 IAHSLTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGK--KLEIMSAQEIDRGQYIC 1712
Query: 617 VPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGD 676
V A K ++V + PP I G +V+ N L LD ++G
Sbjct: 1713 VATSVAGEKEIKYE-VDVLV-------PPAIE---GGDETSYFIVMVNNLLELDCHVTGS 1761
Query: 677 PAPTVIWQ------------KAITQGNKAPARPA-------------------------- 698
P PT++W K + G K A
Sbjct: 1762 PPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFEVT 1821
Query: 699 ---PDAPEDTGDSDEWVFDKK---LLCETEGRVRVETT---KDRSIFTVEGAEK------ 743
P + +G S+ V K L C G T D+ + T +G K
Sbjct: 1822 VHVPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGR 1881
Query: 744 ---------EDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPKISN-VGEDSCTVQWE 793
ED G YT N GE Q ++ + V + P A K+ N S VQ E
Sbjct: 1882 VLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKMLNETVLVSNPVQLE 1941
Query: 794 PPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIG 853
A P++ + + + M + Q + E+ ++ + +Y + A+N+ G
Sbjct: 1942 CKAAGNPVPVITWYKDNRLLSGSTSMTF-LNRGQIIDIESAQISDAGIY--KCVAINSAG 1998
Query: 854 MSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEG- 912
+ + Q + + P ++ V V + V L+ A G+ S+ + +G
Sbjct: 1999 ATELFYSLQ--VHVAPSISGSNNMVAVVVNNPVRLECE------ARGIPAPSLTWLKDGS 2050
Query: 913 -CSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAH-NMAGPGAPVTTTEPVTVQEILQR 970
S + LQ L +G R+L A + G V Q +
Sbjct: 2051 PVSSFSNGLQVL------------SGGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDL 2098
Query: 971 PRLQLPRHL---RQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTD 1027
R+ +P ++ Q + + + V LL P P +TW K+G PL ++ + S
Sbjct: 2099 -RVYVPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLL-KKPGLSISENR 2156
Query: 1028 TILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWK 1087
++L I A+ +G Y +AT V +K + +N+ W
Sbjct: 2157 SVLKIEDAQVQDTGRYTC---------EATNVAGKTEK-----------NYNVNI---WV 2193
Query: 1088 PPQDVGNTELWGYTVQKAD------------------KK--------TMEWFTVLEHYRR 1121
PP G+ EL TV + + KK +M +L R+
Sbjct: 2194 PPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQ 2253
Query: 1122 THCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAP 1181
+ E + + + N+ G + + + V+I RP IT +
Sbjct: 2254 LQISIAEK--SDAALYSCVASNVAGTAKKEYNLQ--VYI-RPTIT-----------NSGS 2297
Query: 1182 SFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIR 1241
T+ +V R G + L C V+G P P ++W K+G L + + + + L+++
Sbjct: 2298 HPTEIIVTR----GKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHI--LQLK 2351
Query: 1242 KPCPFDGGIYVCRATNLQGEARCECRLEVRVP 1273
D G YVC A N+ G + L V P
Sbjct: 2352 NIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAP 2383
Score = 61.2 bits (147), Expect = 6e-09
Identities = 89/380 (23%), Positives = 150/380 (39%), Gaps = 53/380 (13%)
Query: 375 VSKGHKIRLT-VELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAA 433
V+ G + LT + ++ D + W +N ++++++ I A +L + D
Sbjct: 531 VTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTL--ANLSLELKSVKFNDAGE 588
Query: 434 YQCVV----GGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSE-EGAQVKWLK 488
Y C+V G S L V+EPP + P ++Q G V C + ++ W
Sbjct: 589 YHCMVSSEGGSSAASVFLTVQEPPKVTVMP-KNQSFTGGSEVSIMCSATGYPKPKIAWTV 647
Query: 489 DGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGG-----QALAELIVQEK 543
+ + + +YR DG L I A +DAG Y S Q ++
Sbjct: 648 NDMFIVGSH--RYRMTSDGT---LFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAP 702
Query: 544 KLEVYQSIADLMVGAKDQAVFKCEVSDENVRGV-WLKNGKELVPDSRIKVSHIGRVHKLT 602
KL V QS +L+V D V +C+ S V W K EL P + + + + + L
Sbjct: 703 KLMVVQS--ELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLIIDPL--LGLLK 758
Query: 603 IDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVV 662
I + D DY+ V A + K+ ++V V QEP + ++
Sbjct: 759 IQETQDLDAGDYTCVAINEAGRATGKIT-LDVGSPPVFIQEPADVSMEI----------- 806
Query: 663 AGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGD--------SDEWVFD 714
G+ + L + G P PT+ W++ + P P + + W D
Sbjct: 807 -GSNVTLPCYVQGYPEPTIKWRRL----DNMPIFSRPFSVSSISQLRTGALFILNLWASD 861
Query: 715 K-KLLCETE---GRVRVETT 730
K +CE E G+++ ETT
Sbjct: 862 KGTYICEAENQFGKIQSETT 881
Score = 59.7 bits (143), Expect = 2e-08
Identities = 153/716 (21%), Positives = 249/716 (34%), Gaps = 138/716 (19%)
Query: 392 AEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCST----EL 447
A + W K+G ++ + + I + RTL I + Y CV E E+
Sbjct: 2605 ATITWFKDGTPLESNRNIRI---LPGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEV 2661
Query: 448 FVKEPPVLITRPL-------EDQLVMVGQRVEFECEV-SEEGAQVKWLKDGVELTREETF 499
V PP++ L ++ + V + ECE + A + W KDG L ++
Sbjct: 2662 KVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHV 2721
Query: 500 KYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLM-VG- 557
H L I EA + D G Y C + A + + + ++V S L +G
Sbjct: 2722 NIA----ANGHTLQIKEAQISDTGRYT-CVASNIAGEDELDFDVNIQVPPSFQKLWEIGN 2776
Query: 558 ---------AKDQAV-----FKCEVSDENVRGV-WLKNGKELVPDSRIKVSHIGRVHKLT 602
AKD + CE + + W K+G L ++ + GRV L
Sbjct: 2777 MLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRV--LQ 2834
Query: 603 IDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVV 662
I D Y+ V A N + E + + R P I +P+ + V+
Sbjct: 2835 IPRAKVEDAGRYTCV----AVNEAG-----EDSLQYDVRVLVPPIIKGANSDLPEEVTVL 2885
Query: 663 AGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETE 722
++ SG PAP WQK D + D +
Sbjct: 2886 VNKSALIECLSSGSPAPRNSWQK---------------------DGQPLLEDDHHKFLSN 2924
Query: 723 GRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPK--- 779
GR I + + D G Y +N G + + V VP + PK
Sbjct: 2925 GR----------ILQILNTQITDIGRYVCVAENTAGSAKKYFNLNV-HVPPSVIGPKSEN 2973
Query: 780 ----ISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARR 835
++N +C V PP P L ++ K+ + ++LN + + +
Sbjct: 2974 LTVVVNNFISLTCEVSGFPP------PDLSWL------KNEQPIKLNTNTLIVPGGRTLQ 3021
Query: 836 MIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTH----LAVEDVSD-TTVSLKW 890
+I V + Y AI + S PPS H L+V +V + T+VSL+
Sbjct: 3022 IIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLEC 3081
Query: 891 RPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMA 950
P W + +TE T + + L G L ++ ++
Sbjct: 3082 ES--------------NAVPPPVITWYKNGRMITESTHVEI--LADGQML--HIKKAEVS 3123
Query: 951 GPGAPVTTTEPVTVQE-------ILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRP 1003
G V V ++ + P ++ P R+ I + + PV L G P P
Sbjct: 3124 DTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPE--REVIVETISNPVTLTCDATGIPPP 3181
Query: 1004 QVTWTKEGQPLAGE---EVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKA 1056
+ W K + + EV I + + ++ AR HS + T NME KA
Sbjct: 3182 TIAWLKNHKRIENSDSLEVRILSGGSK----LQIARSQHSDSGNYTCIASNMEGKA 3233
Score = 53.5 bits (127), Expect = 1e-06
Identities = 32/86 (37%), Positives = 41/86 (47%), Gaps = 3/86 (3%)
Query: 1175 LDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQG 1234
L E P T N+S G + C+ G PKPKI+W N + + R+RM S
Sbjct: 606 LTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDG- 664
Query: 1235 VLTLEIRKPCPFDGGIYVCRATNLQG 1260
TL I+ P D GIY C A+N G
Sbjct: 665 --TLFIKNAAPKDAGIYGCLASNSAG 688
Score = 48.9 bits (115), Expect = 3e-05
Identities = 31/93 (33%), Positives = 38/93 (40%)
Query: 1181 PSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEI 1240
PS N +VI L C G PKP I+W KNG L D + +L I
Sbjct: 3804 PSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVI 3863
Query: 1241 RKPCPFDGGIYVCRATNLQGEARCECRLEVRVP 1273
P D Y C TN G+ + L V+VP
Sbjct: 3864 ISPSVDDTATYECTVTNGAGDDKRTVDLTVQVP 3896
Score = 48.5 bits (114), Expect = 4e-05
Identities = 32/96 (33%), Positives = 43/96 (44%), Gaps = 4/96 (4%)
Query: 1179 EAPSFTQPLVNRSVIA-GYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLT 1237
+ P P + VIA L C G P P I+W K+G + E R R+ S +
Sbjct: 4076 QVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSG---S 4132
Query: 1238 LEIRKPCPFDGGIYVCRATNLQGEARCECRLEVRVP 1273
L+I P D G Y C A N+ G + +L V VP
Sbjct: 4133 LQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVP 4168
Score = 47.4 bits (111), Expect = 9e-05
Identities = 66/301 (21%), Positives = 118/301 (39%), Gaps = 33/301 (10%)
Query: 394 VKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCV----VGGEKCSTELFV 449
+ +++NG + + +Y+ ES A L I++ +L+D+ Y+C+ G + T V
Sbjct: 461 LSFVRNG--VTLGVDQYLKES--ASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDV 516
Query: 450 KEPPVLITRPLEDQLVMVGQRVEFEC-EVSEEGAQVKWLKDGVELTREETFKYRFKKDGQ 508
EPP +I P + V G+R C +S + W ++ ++ E + R +
Sbjct: 517 SEPPPVIQVP-NNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLAN-- 573
Query: 509 RHHLIINEAMLEDAGHY--ALCTSGGQALAE--LIVQEKKLEVYQSIADLMVGAKDQAVF 564
L + DAG Y + + GG + A L VQE G + ++
Sbjct: 574 -LSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGGSEVSIM 632
Query: 565 KCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACN 624
+ W N +V R +++ G L I + P D Y G +
Sbjct: 633 CSATGYPKPKIAWTVNDMFIVGSHRYRMTSDG---TLFIKNAAPKDAGIY-----GCLAS 684
Query: 625 LSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQ 684
SA + ++ E PK+ + + ++V G+ ++ SG P P V W
Sbjct: 685 NSAGTDKQNSTLRYI---EAPKLMV-----VQSELLVALGDITVMECKTSGIPPPQVKWF 736
Query: 685 K 685
K
Sbjct: 737 K 737
Score = 46.6 bits (109), Expect = 2e-04
Identities = 72/298 (24%), Positives = 109/298 (36%), Gaps = 71/298 (23%)
Query: 999 GKPRPQVTWTKEGQPLAGEEV--SIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKA 1056
G P+P + W K G L ++ S R + +++ I + + TY+ TV +DK
Sbjct: 3829 GIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVD-DTATYECTVTNGAGDDKR 3887
Query: 1057 TLVLQVVDKPS---PPQDLRVTDA------------------WGLNVALEWKPPQDVGNT 1095
T+ L V PS P D VT W N + P D
Sbjct: 3888 TVDLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKN-GIRLLPRGD---- 3942
Query: 1096 ELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTK 1155
GY + + + T L H R CV ++N G + R T
Sbjct: 3943 ---GYRILSSGAIEI-LATQLNHAGRYTCV---------------ARNAAGSAHRHVTLH 3983
Query: 1156 EPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWF 1215
+EPP + PS ++N ++ L C G+P P I+W
Sbjct: 3984 ----------VHEPPVIQP-----QPSELHVILNNPIL------LPCEATGTPSPFITWQ 4022
Query: 1216 KNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVRVP 1273
K G+++ R G L+I + D G Y+C A N G A + +L V+VP
Sbjct: 4023 KEGINVNTSGRNHAVLPSG--GLQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQVP 4078
Score = 45.8 bits (107), Expect = 3e-04
Identities = 122/543 (22%), Positives = 198/543 (36%), Gaps = 84/543 (15%)
Query: 168 VGGSITFSARVAGASLLKPPVVKWFKGKWVDLSSKVGQHLQLHDSYDRASKVYLFELHIT 227
V SI R G PP + W K L + H++L A +V + I
Sbjct: 3356 VDTSINIECRATGTP---PPQINWLKN---GLPLPLSSHIRLL----AAGQV----IRIV 3401
Query: 228 DAQPAFTGSYRCEVSTKDKFDCSNFNLTVH------EAMGTGDLDLLSAFRRTSLAGGGR 281
AQ + Y C S + D ++NL V +MGT ++ +L TS+A
Sbjct: 3402 RAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLKG-SSTSMAC--- 3457
Query: 282 RISDSHEDTGILDFSSLLKKRDSFRTPRDSKLEAPAEEDVWEILRQAPPS--EYERIAF- 338
I+D S+ RD D+ L V ++L+ +Y IA
Sbjct: 3458 -ITDG------TPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASN 3510
Query: 339 QYGVTDLRGMLKRLK-----GMRRDEKKSTAFQKKLEPAYQVSKGHKIRLTVELADHDAE 393
+ G +LK L+ G E+ S LE S ++T
Sbjct: 3511 EAGEVSKHFILKVLEPPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMT--------- 3561
Query: 394 VKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVV----GGEKCSTELFV 449
W+K+G+ + + +++G L IS + D Y C+ G + + V
Sbjct: 3562 --WMKDGRPLPQTDQ---VQTLGGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRV 3616
Query: 450 KEPPVLI-TRPLEDQLVMVGQRVEFECEVSEEGAQV-KWLKDGVELTREETFKYRFKKDG 507
PP + T D V+ ++V EC+ V WL++G L + T + R G
Sbjct: 3617 HVPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERL--QATPRVRILSGG 3674
Query: 508 QRHHLIINEAMLEDAGHYALCTSG--GQALAELIVQEK-KLEVYQSIADLMVGAKDQAVF 564
+ +L IN A L D +Y S G+ E I+ + L++ V
Sbjct: 3675 R--YLQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKSTVL 3732
Query: 565 KCEVSD-ENVRGVWLKNGKELVPD-SRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFA 622
+C R W K+G L + +R + G +H I D Y + A
Sbjct: 3733 ECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLH---IQSAHVTDTGRYLCMATNAA 3789
Query: 623 CNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVI 682
++ ++V + PP I PG P + V+ + L +G P P++
Sbjct: 3790 GTDRRRID-LQVHV-------PPSI---APG--PTNMTVIVNVQTTLACEATGIPKPSIN 3836
Query: 683 WQK 685
W+K
Sbjct: 3837 WRK 3839
Score = 44.7 bits (104), Expect = 6e-04
Identities = 38/118 (32%), Positives = 51/118 (43%), Gaps = 17/118 (14%)
Query: 1159 FIPRPGITY--EPPNYKALDFSEAPS-FTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWF 1215
F+ G Y EPP +K + PS + +PL G A+L C V+G P P I W
Sbjct: 4336 FVKAIGFVYVKEPPVFKG----DYPSNWIEPL-------GGNAILNCEVKGDPTPTIQWN 4384
Query: 1216 KNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVRVP 1273
+ G+D+ R R G +L I D G Y C ATN G L ++ P
Sbjct: 4385 RKGVDIEISHRIRQL---GNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSP 4439
Score = 42.0 bits (97), Expect = 0.004
Identities = 29/99 (29%), Positives = 42/99 (42%), Gaps = 2/99 (2%)
Query: 1175 LDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQG 1234
L + EAP V G ++ C G P P++ WFK L+L + G
Sbjct: 696 LRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLG 755
Query: 1235 VLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVRVP 1273
+ L+I++ D G Y C A N G A + L+V P
Sbjct: 756 L--LKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSP 792
Score = 39.7 bits (91), Expect = 0.019
Identities = 62/285 (21%), Positives = 97/285 (34%), Gaps = 28/285 (9%)
Query: 988 GEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTV 1047
G V+++ G P+P++ WT + G S D LFI+ A +G Y
Sbjct: 626 GSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTS--DGTLFIKNAAPKDAGIYGCLA 683
Query: 1048 RIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADK 1107
DK L+ ++ P L V + L VAL G+ +
Sbjct: 684 SNSAGTDKQNSTLRYIEAPK----LMVVQS-ELLVAL--------GDITVMECKTSGIPP 730
Query: 1108 KTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITY 1167
++WF R + ++ + ++G ++ + D IT
Sbjct: 731 PQVKWFKGDLELRPSTFLIIDPLLG---LLKIQETQDLDAGDYTCVAINEAGRATGKIT- 786
Query: 1168 EPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISW--FKNGLDLGEDA 1225
LD P F Q + S+ G L C V+G P+P I W N
Sbjct: 787 -------LDVGSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPF 839
Query: 1226 RFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
S+ L I D G Y+C A N G+ + E + V
Sbjct: 840 SVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTV 884
Score = 39.3 bits (90), Expect = 0.024
Identities = 30/100 (30%), Positives = 45/100 (45%), Gaps = 5/100 (5%)
Query: 1176 DFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLD--LGEDARFRMFSKQ 1233
D SE P Q N +V G A+L C + + ++W +N D L E AR R +
Sbjct: 515 DVSEPPPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLAN- 573
Query: 1234 GVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVRVP 1273
L+LE++ D G Y C ++ G + L V+ P
Sbjct: 574 --LSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEP 611
Score = 38.9 bits (89), Expect = 0.032
Identities = 59/294 (20%), Positives = 117/294 (39%), Gaps = 57/294 (19%)
Query: 484 VKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHY---ALCTSG-GQALAELI 539
+ ++++GV L ++ + K+ +L I + L D G Y A+ ++G G+A
Sbjct: 461 LSFVRNGVTLGVDQ-----YLKESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFD 515
Query: 540 VQEKKLEVYQSIADLMVGAKDQAVFKCEV-SDENVRGVWLKNGKELVPDSRIKVSHIGRV 598
V E V Q ++ V ++AV C + S + W +N +++ ++ + +
Sbjct: 516 VSEPP-PVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANL 574
Query: 599 HKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDT 658
L + V D +Y + + +A + F+ QEPPK+ + +P
Sbjct: 575 -SLELKSVKFNDAGEYHCMVSSEGGSSAASV--------FLTVQEPPKVTV-----MPKN 620
Query: 659 IVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLL 718
G+++ + +G P P + W +D ++
Sbjct: 621 QSFTGGSEVSIMCSATGYPKPKIAWTV----------------------NDMFIV----- 653
Query: 719 CETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVP 772
G R T D ++F ++ A +D G+Y N G D+ N T++ I+ P
Sbjct: 654 ----GSHRYRMTSDGTLF-IKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAP 702
Score = 35.4 bits (80), Expect = 0.35
Identities = 20/84 (23%), Positives = 37/84 (44%), Gaps = 7/84 (8%)
Query: 16 PRSVEVAAGSPAVFEAETERA-GVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPA 74
P+ V++ + E E + W + G + + + +A G HTL ++E +
Sbjct: 2681 PKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANG--HTLQIKEAQIS 2738
Query: 75 DQGSYAV----IAGSSKVKFDLKV 94
D G Y IAG ++ FD+ +
Sbjct: 2739 DTGRYTCVASNIAGEDELDFDVNI 2762
Score = 32.7 bits (73), Expect = 2.3
Identities = 20/65 (30%), Positives = 31/65 (47%), Gaps = 7/65 (10%)
Query: 39 KVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYAVI----AGSSKVKFDLKV 94
K+ W I S++Y + ++GT L ++ P D G Y + AG+ K L+
Sbjct: 642 KIAWTVNDMFIVGSHRYRMTSDGT---LFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRY 698
Query: 95 IEAEK 99
IEA K
Sbjct: 699 IEAPK 703
Score = 32.3 bits (72), Expect = 3.0
Identities = 32/139 (23%), Positives = 54/139 (38%), Gaps = 16/139 (11%)
Query: 40 VRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYAV----IAGSSKVKFDLKVI 95
+ W +GGS + ++ ++ TL++ + P+D G Y IAG+ + + L V
Sbjct: 1202 ITWSKGGSTMLVDGEHHVSNPDG--TLSIDQATPSDAGIYTCVATNIAGTDETEITLHVQ 1259
Query: 96 EAEKAEPMLAPAPAPAEATGAPGEAPAPAAELGESAPSPKG-SSSAALNGPTPGAPDDPI 154
E E + P + A P G P+ K + L G PG
Sbjct: 1260 EPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGRELTGREPG------ 1313
Query: 155 GLFVMRPQDGEVTVGGSIT 173
+ +DG + V S+T
Sbjct: 1314 ---ISILEDGTLLVIASVT 1329
Score = 32.0 bits (71), Expect = 3.9
Identities = 23/71 (32%), Positives = 34/71 (47%), Gaps = 4/71 (5%)
Query: 1191 SVIAGYTAML-CCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGG 1249
+VI G L C + G+P P+ W KN L ++ + S +L I + DGG
Sbjct: 900 NVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDG---SLHIERVQLQDGG 956
Query: 1250 IYVCRATNLQG 1260
Y C A+N+ G
Sbjct: 957 EYTCVASNVAG 967
Score = 31.6 bits (70), Expect = 5.1
Identities = 29/142 (20%), Positives = 59/142 (41%), Gaps = 15/142 (10%)
Query: 389 DHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGE----KCS 444
D ++W + G +I++S + +G +L I D Y CV E + S
Sbjct: 4376 DPTPTIQWNRKGVDIEIS---HRIRQLG-NGSLAIYGTVNEDAGDYTCVATNEAGVVERS 4431
Query: 445 TELFVKEPPVLITRPLEDQLVMVGQRVEFECEVS-EEGAQVKWLKDGVELTREETFKYRF 503
L ++ PP++ P+E ++ G ++ C+ + E + W + G ++ ++
Sbjct: 4432 MSLTLQSPPIITLEPVE-TVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVL- 4489
Query: 504 KKDGQRHHLIINEAMLEDAGHY 525
+ L I +A ED +
Sbjct: 4490 ----SNNSLYIADAQKEDTSEF 4507
>gi|193083163 roundabout, axon guidance receptor, homolog 2 isoform
ROBO2a [Homo sapiens]
Length = 1394
Score = 108 bits (271), Expect = 2e-23
Identities = 148/592 (25%), Positives = 240/592 (40%), Gaps = 98/592 (16%)
Query: 421 LTISQCSLADDAAYQCV---VGGEKCS--TELFVKEPPVLITRPLEDQLVMVGQRVEFEC 475
L IS +D Y CV + GE+ S EL V E P + RP+ +Q+V+ + VEF C
Sbjct: 204 LMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRRPI-NQVVLEEEAVEFRC 262
Query: 476 EVS-EEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGG-- 532
+V + V+W KD +L R +Y K D + L I + M D G Y +C +
Sbjct: 263 QVQGDPQPTVRWKKDDADLPRG---RYDIKDD---YTLRIKKTMSTDEGTY-MCIAENRV 315
Query: 533 ---QALAELIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDENVRGV-WLKNGKELV--- 585
+A A L V+ V + D +V F CE V W K G + +
Sbjct: 316 GKMEASATLTVRAPPQFVVRP-RDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFP 374
Query: 586 -----PDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVP 640
P+SR VS G LTI ++ +D Y A ++ AK ++++ V
Sbjct: 375 NQPQQPNSRCSVSPTG---DLTITNIQRSDAGYYICQALTVAGSILAKA---QLEVTDVL 428
Query: 641 RQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPD 700
PP I L P + + V G L L +GDP P + W K +G P R
Sbjct: 429 TDRPPPIILQGPA---NQTLAVDGTAL-LKCKATGDPLPVISWLK---EGFTFPGR---- 477
Query: 701 APEDTGDSDEWVFDKKLLCETEGRVRVETTK--DRSIFTVEGAEKEDEGVYTVTVKNPVG 758
D + + +G ++++ + D +T E ++ +
Sbjct: 478 -------------DPRATIQEQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTES 524
Query: 759 EDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRW 818
++ + D+P P+ P++++V ++S T+ W+ P G P YI+E +
Sbjct: 525 GATISKNYDLSDLPGPPSKPQVTDVTKNSVTLSWQ-PGTPGTLPASAYIIEAFSQSVSNS 583
Query: 819 MRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPF--MPIGPPSEPT-H 875
+ + ++ + R + +Y V A+N G+S PSP S P I PP++ H
Sbjct: 584 WQTVANHVKTTLYTVRGLRPNTIYLFMVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDH 643
Query: 876 LAVED--------------VSDTTVSLKW---RPPERVGAGGLDGYSVEYCPEGCSEWVA 918
V+ ++ TTV + W R P+ + GY V Y + +
Sbjct: 644 RQVQKELGDVLVRLHNPVVLTPTTVQVTWTVDRQPQFI-----QGYRVMYRQTSGLQATS 698
Query: 919 ALQGL-----TEHTSILVKDLPTGARLLFRVRAH-----NMAGPGAPVTTTE 960
+ Q L TE +++LV +L G +VR + M V TTE
Sbjct: 699 SWQNLDAKVPTERSAVLV-NLKKGVTYEIKVRPYFNEFQGMDSESKTVRTTE 749
Score = 77.8 bits (190), Expect = 6e-14
Identities = 176/799 (22%), Positives = 284/799 (35%), Gaps = 161/799 (20%)
Query: 375 VSKGHKIRLTVELADHDAE-VKWLKNGQEIQM-------------SGSKYIFESIGAKRT 420
VSKG L + ++W K+G+ ++ SGS + + +R
Sbjct: 58 VSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRR- 116
Query: 421 LTISQCSLADDAAYQCVVG---GEKCSTELFVKEPPVL--ITRPLEDQLVMVGQRVEFEC 475
S D+ +Y CV GE S ++ + + D +V G+ EC
Sbjct: 117 ------SKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPAILEC 170
Query: 476 EVSEEGAQ--VKWLKDGVELT-REETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSG- 531
+ + + W KD V + +EE R K L+I+ DAG Y +
Sbjct: 171 QPPRGHPEPTIYWKKDKVRIDDKEERISIRGGK------LMISNTRKSDAGMYTCVGTNM 224
Query: 532 ----GQALAELIVQEKKLEVYQSIADLMVGAKDQAV-FKCEVSDENVRGV-WLKNGKELV 585
AEL V E+ + + I +++ +++AV F+C+V + V W K+ +L
Sbjct: 225 VGERDSDPAELTVFERPTFLRRPINQVVL--EEEAVEFRCQVQGDPQPTVRWKKDDADL- 281
Query: 586 PDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPP 645
P R + + L I DE Y + E ++ ME R P
Sbjct: 282 PRGRYDIKDD---YTLRIKKTMSTDEGTYMCIAEN-------RVGKMEASATLTVRAPPQ 331
Query: 646 KIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDT 705
+ P +V G + G+P P V WQK +Q P +P
Sbjct: 332 FVVR------PRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQ------- 378
Query: 706 GDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLT 765
+ R V T D T+ ++ D G Y G
Sbjct: 379 --------------QPNSRCSVSPTGD---LTITNIQRSDAGYYICQALTVAGSILAKAQ 421
Query: 766 VKVIDV-------------------PDAPAAPKISNVGEDSCTVQW--EPPAYDGGQPIL 804
++V DV D A K G+ + W E + G P
Sbjct: 422 LEVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRA 481
Query: 805 GYILERKKKKSYRWMRLN----FDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPA 860
++ + + +R++ + + S G V V G +
Sbjct: 482 --TIQEQGTLQIKNLRISDTGTYTCVATSS-------SGETSWSAVLDVTESGATISKNY 532
Query: 861 SQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAAL 920
+P GPPS+P V DV+ +V+L W+P G Y +E + S +
Sbjct: 533 DLSDLP-GPPSKPQ---VTDVTKNSVTLSWQPGTP-GTLPASAYIIEAFSQSVSNSWQTV 587
Query: 921 QGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLR 980
+ T V+ L LF VRA N G P ++PV Q+I P Q H
Sbjct: 588 ANHVKTTLYTVRGLRPNTIYLFMVRAINPQGLSDPSPMSDPVRTQDI--SPPAQGVDH-- 643
Query: 981 QTIQKKVGEP-VNLLIPFQGKPRP-QVTWTKEGQP--LAGEEVSIRNS------------ 1024
+ +QK++G+ V L P P QVTWT + QP + G V R +
Sbjct: 644 RQVQKELGDVLVRLHNPVVLTPTTVQVTWTVDRQPQFIQGYRVMYRQTSGLQATSSWQNL 703
Query: 1025 ----PTD-TILFIRAARRVHSGTYQVTVR-----IENMEDKATLVLQVVDKPS-PPQDLR 1073
PT+ + + + + V TY++ VR + M+ ++ V + PS PPQ +
Sbjct: 704 DAKVPTERSAVLVNLKKGV---TYEIKVRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVT 760
Query: 1074 VTDAWGLN---VALEWKPP 1089
V N +++ W PP
Sbjct: 761 VLTVGSYNSTSISVSWDPP 779
Score = 62.8 bits (151), Expect = 2e-09
Identities = 70/297 (23%), Positives = 114/297 (38%), Gaps = 39/297 (13%)
Query: 988 GEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNS----PTDTILFIRAAR----RVH 1039
GEP L +G+P P + W K+G+ + ++ R+ P+ ++ F+R +
Sbjct: 61 GEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPD 120
Query: 1040 SGTYQVTVRI---ENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTE 1096
G+Y R E + A+L + ++ V A G LE +PP+ G+ E
Sbjct: 121 EGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPR--GHPE 178
Query: 1097 LWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKE 1156
Y K DK ++ R ++ + + NMVG D +
Sbjct: 179 PTIY--WKKDKVRIDDKEERISIRGGKLMISNTRKSDAGMYTCVGTNMVGERD-----SD 231
Query: 1157 PVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFK 1216
P L E P+F + +N+ V+ C V+G P+P + W K
Sbjct: 232 PA---------------ELTVFERPTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKK 276
Query: 1217 NGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVRVP 1273
+ DL + + TL I+K D G Y+C A N G+ L VR P
Sbjct: 277 DDADLPRG----RYDIKDDYTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAP 329
Score = 60.5 bits (145), Expect = 1e-08
Identities = 88/313 (28%), Positives = 121/313 (38%), Gaps = 50/313 (15%)
Query: 976 PRHLRQTIQKKV--GEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIR 1033
P LR+ I + V E V QG P+P V W K+ L I++ D L I+
Sbjct: 241 PTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKD---DYTLRIK 297
Query: 1034 AARRVHSGTYQVTV--RIENMEDKATLVLQVVDKPSPPQDL-RVTD---AWGLNVALEWK 1087
GTY R+ ME ATL ++ +PPQ + R D A G V
Sbjct: 298 KTMSTDEGTYMCIAENRVGKMEASATLTVR-----APPQFVVRPRDQIVAQGRTVTF--- 349
Query: 1088 PPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVP---ELIIGN------GYYFR 1138
P + GN + + ++ + + F + C V +L I N GYY
Sbjct: 350 PCETKGNPQPAVFWQKEGSQNLL--FPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYY-- 405
Query: 1139 VFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTA 1198
+ V S A E + +T PP P Q N+++ TA
Sbjct: 406 ICQALTVAGSILAKAQLEVTDV----LTDRPP----------PIILQGPANQTLAVDGTA 451
Query: 1199 MLCCAVRGSPKPKISWFKNGLDL-GEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATN 1257
+L C G P P ISW K G G D R +QG TL+I+ D G Y C AT+
Sbjct: 452 LLKCKATGDPLPVISWLKEGFTFPGRDPR-ATIQEQG--TLQIKNLRISDTGTYTCVATS 508
Query: 1258 LQGEARCECRLEV 1270
GE L+V
Sbjct: 509 SSGETSWSAVLDV 521
Score = 50.1 bits (118), Expect = 1e-05
Identities = 46/165 (27%), Positives = 62/165 (37%), Gaps = 16/165 (9%)
Query: 999 GKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATL 1058
G P P ++W KEG G + T L I+ R +GTY + E +
Sbjct: 459 GDPLPVISWLKEGFTFPGRDPRATIQEQGT-LQIKNLRISDTGTYTCVATSSSGETSWSA 517
Query: 1059 VLQVV-------------DKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQK- 1104
VL V D P PP +VTD +V L W+P G Y ++
Sbjct: 518 VLDVTESGATISKNYDLSDLPGPPSKPQVTDVTKNSVTLSWQPGTP-GTLPASAYIIEAF 576
Query: 1105 ADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSD 1149
+ + W TV H + T V L Y F V + N G SD
Sbjct: 577 SQSVSNSWQTVANHVKTTLYTVRGLRPNTIYLFMVRAINPQGLSD 621
Score = 37.0 bits (84), Expect = 0.12
Identities = 28/79 (35%), Positives = 33/79 (41%), Gaps = 9/79 (11%)
Query: 1192 VIAGYTAMLCCAVRGSPKPKISWFKNG----LDLGEDARFRMFSKQGVL----TLEIRKP 1243
V G L C G P P I W+K+G D + RM G L + R+
Sbjct: 58 VSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRS 117
Query: 1244 CPFDGGIYVCRATNLQGEA 1262
P D G YVC A N GEA
Sbjct: 118 KP-DEGSYVCVARNYLGEA 135
>gi|61888896 roundabout, axon guidance receptor, homolog 2 isoform
ROBO2b [Homo sapiens]
Length = 1378
Score = 108 bits (271), Expect = 2e-23
Identities = 148/592 (25%), Positives = 240/592 (40%), Gaps = 98/592 (16%)
Query: 421 LTISQCSLADDAAYQCV---VGGEKCS--TELFVKEPPVLITRPLEDQLVMVGQRVEFEC 475
L IS +D Y CV + GE+ S EL V E P + RP+ +Q+V+ + VEF C
Sbjct: 188 LMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRRPI-NQVVLEEEAVEFRC 246
Query: 476 EVS-EEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGG-- 532
+V + V+W KD +L R +Y K D + L I + M D G Y +C +
Sbjct: 247 QVQGDPQPTVRWKKDDADLPRG---RYDIKDD---YTLRIKKTMSTDEGTY-MCIAENRV 299
Query: 533 ---QALAELIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDENVRGV-WLKNGKELV--- 585
+A A L V+ V + D +V F CE V W K G + +
Sbjct: 300 GKMEASATLTVRAPPQFVVRP-RDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFP 358
Query: 586 -----PDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVP 640
P+SR VS G LTI ++ +D Y A ++ AK ++++ V
Sbjct: 359 NQPQQPNSRCSVSPTG---DLTITNIQRSDAGYYICQALTVAGSILAKA---QLEVTDVL 412
Query: 641 RQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPD 700
PP I L P + + V G L L +GDP P + W K +G P R
Sbjct: 413 TDRPPPIILQGPA---NQTLAVDGTAL-LKCKATGDPLPVISWLK---EGFTFPGR---- 461
Query: 701 APEDTGDSDEWVFDKKLLCETEGRVRVETTK--DRSIFTVEGAEKEDEGVYTVTVKNPVG 758
D + + +G ++++ + D +T E ++ +
Sbjct: 462 -------------DPRATIQEQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTES 508
Query: 759 EDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRW 818
++ + D+P P+ P++++V ++S T+ W+ P G P YI+E +
Sbjct: 509 GATISKNYDLSDLPGPPSKPQVTDVTKNSVTLSWQ-PGTPGTLPASAYIIEAFSQSVSNS 567
Query: 819 MRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPF--MPIGPPSEPT-H 875
+ + ++ + R + +Y V A+N G+S PSP S P I PP++ H
Sbjct: 568 WQTVANHVKTTLYTVRGLRPNTIYLFMVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDH 627
Query: 876 LAVED--------------VSDTTVSLKW---RPPERVGAGGLDGYSVEYCPEGCSEWVA 918
V+ ++ TTV + W R P+ + GY V Y + +
Sbjct: 628 RQVQKELGDVLVRLHNPVVLTPTTVQVTWTVDRQPQFI-----QGYRVMYRQTSGLQATS 682
Query: 919 ALQGL-----TEHTSILVKDLPTGARLLFRVRAH-----NMAGPGAPVTTTE 960
+ Q L TE +++LV +L G +VR + M V TTE
Sbjct: 683 SWQNLDAKVPTERSAVLV-NLKKGVTYEIKVRPYFNEFQGMDSESKTVRTTE 733
Score = 77.8 bits (190), Expect = 6e-14
Identities = 176/799 (22%), Positives = 284/799 (35%), Gaps = 161/799 (20%)
Query: 375 VSKGHKIRLTVELADHDAE-VKWLKNGQEIQM-------------SGSKYIFESIGAKRT 420
VSKG L + ++W K+G+ ++ SGS + + +R
Sbjct: 42 VSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRR- 100
Query: 421 LTISQCSLADDAAYQCVVG---GEKCSTELFVKEPPVL--ITRPLEDQLVMVGQRVEFEC 475
S D+ +Y CV GE S ++ + + D +V G+ EC
Sbjct: 101 ------SKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPAILEC 154
Query: 476 EVSEEGAQ--VKWLKDGVELT-REETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSG- 531
+ + + W KD V + +EE R K L+I+ DAG Y +
Sbjct: 155 QPPRGHPEPTIYWKKDKVRIDDKEERISIRGGK------LMISNTRKSDAGMYTCVGTNM 208
Query: 532 ----GQALAELIVQEKKLEVYQSIADLMVGAKDQAV-FKCEVSDENVRGV-WLKNGKELV 585
AEL V E+ + + I +++ +++AV F+C+V + V W K+ +L
Sbjct: 209 VGERDSDPAELTVFERPTFLRRPINQVVL--EEEAVEFRCQVQGDPQPTVRWKKDDADL- 265
Query: 586 PDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPP 645
P R + + L I DE Y + E ++ ME R P
Sbjct: 266 PRGRYDIKDD---YTLRIKKTMSTDEGTYMCIAEN-------RVGKMEASATLTVRAPPQ 315
Query: 646 KIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDT 705
+ P +V G + G+P P V WQK +Q P +P
Sbjct: 316 FVVR------PRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQ------- 362
Query: 706 GDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLT 765
+ R V T D T+ ++ D G Y G
Sbjct: 363 --------------QPNSRCSVSPTGD---LTITNIQRSDAGYYICQALTVAGSILAKAQ 405
Query: 766 VKVIDV-------------------PDAPAAPKISNVGEDSCTVQW--EPPAYDGGQPIL 804
++V DV D A K G+ + W E + G P
Sbjct: 406 LEVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRA 465
Query: 805 GYILERKKKKSYRWMRLN----FDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPA 860
++ + + +R++ + + S G V V G +
Sbjct: 466 --TIQEQGTLQIKNLRISDTGTYTCVATSS-------SGETSWSAVLDVTESGATISKNY 516
Query: 861 SQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAAL 920
+P GPPS+P V DV+ +V+L W+P G Y +E + S +
Sbjct: 517 DLSDLP-GPPSKPQ---VTDVTKNSVTLSWQPGTP-GTLPASAYIIEAFSQSVSNSWQTV 571
Query: 921 QGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLR 980
+ T V+ L LF VRA N G P ++PV Q+I P Q H
Sbjct: 572 ANHVKTTLYTVRGLRPNTIYLFMVRAINPQGLSDPSPMSDPVRTQDI--SPPAQGVDH-- 627
Query: 981 QTIQKKVGEP-VNLLIPFQGKPRP-QVTWTKEGQP--LAGEEVSIRNS------------ 1024
+ +QK++G+ V L P P QVTWT + QP + G V R +
Sbjct: 628 RQVQKELGDVLVRLHNPVVLTPTTVQVTWTVDRQPQFIQGYRVMYRQTSGLQATSSWQNL 687
Query: 1025 ----PTD-TILFIRAARRVHSGTYQVTVR-----IENMEDKATLVLQVVDKPS-PPQDLR 1073
PT+ + + + + V TY++ VR + M+ ++ V + PS PPQ +
Sbjct: 688 DAKVPTERSAVLVNLKKGV---TYEIKVRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVT 744
Query: 1074 VTDAWGLN---VALEWKPP 1089
V N +++ W PP
Sbjct: 745 VLTVGSYNSTSISVSWDPP 763
Score = 62.8 bits (151), Expect = 2e-09
Identities = 70/297 (23%), Positives = 114/297 (38%), Gaps = 39/297 (13%)
Query: 988 GEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNS----PTDTILFIRAAR----RVH 1039
GEP L +G+P P + W K+G+ + ++ R+ P+ ++ F+R +
Sbjct: 45 GEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPD 104
Query: 1040 SGTYQVTVRI---ENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTE 1096
G+Y R E + A+L + ++ V A G LE +PP+ G+ E
Sbjct: 105 EGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPR--GHPE 162
Query: 1097 LWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKE 1156
Y K DK ++ R ++ + + NMVG D +
Sbjct: 163 PTIY--WKKDKVRIDDKEERISIRGGKLMISNTRKSDAGMYTCVGTNMVGERD-----SD 215
Query: 1157 PVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFK 1216
P L E P+F + +N+ V+ C V+G P+P + W K
Sbjct: 216 PA---------------ELTVFERPTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKK 260
Query: 1217 NGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVRVP 1273
+ DL + + TL I+K D G Y+C A N G+ L VR P
Sbjct: 261 DDADLPRG----RYDIKDDYTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAP 313
Score = 60.5 bits (145), Expect = 1e-08
Identities = 88/313 (28%), Positives = 121/313 (38%), Gaps = 50/313 (15%)
Query: 976 PRHLRQTIQKKV--GEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIR 1033
P LR+ I + V E V QG P+P V W K+ L I++ D L I+
Sbjct: 225 PTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKD---DYTLRIK 281
Query: 1034 AARRVHSGTYQVTV--RIENMEDKATLVLQVVDKPSPPQDL-RVTD---AWGLNVALEWK 1087
GTY R+ ME ATL ++ +PPQ + R D A G V
Sbjct: 282 KTMSTDEGTYMCIAENRVGKMEASATLTVR-----APPQFVVRPRDQIVAQGRTVTF--- 333
Query: 1088 PPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVP---ELIIGN------GYYFR 1138
P + GN + + ++ + + F + C V +L I N GYY
Sbjct: 334 PCETKGNPQPAVFWQKEGSQNLL--FPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYY-- 389
Query: 1139 VFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTA 1198
+ V S A E + +T PP P Q N+++ TA
Sbjct: 390 ICQALTVAGSILAKAQLEVTDV----LTDRPP----------PIILQGPANQTLAVDGTA 435
Query: 1199 MLCCAVRGSPKPKISWFKNGLDL-GEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATN 1257
+L C G P P ISW K G G D R +QG TL+I+ D G Y C AT+
Sbjct: 436 LLKCKATGDPLPVISWLKEGFTFPGRDPR-ATIQEQG--TLQIKNLRISDTGTYTCVATS 492
Query: 1258 LQGEARCECRLEV 1270
GE L+V
Sbjct: 493 SSGETSWSAVLDV 505
Score = 50.1 bits (118), Expect = 1e-05
Identities = 46/165 (27%), Positives = 62/165 (37%), Gaps = 16/165 (9%)
Query: 999 GKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATL 1058
G P P ++W KEG G + T L I+ R +GTY + E +
Sbjct: 443 GDPLPVISWLKEGFTFPGRDPRATIQEQGT-LQIKNLRISDTGTYTCVATSSSGETSWSA 501
Query: 1059 VLQVV-------------DKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQK- 1104
VL V D P PP +VTD +V L W+P G Y ++
Sbjct: 502 VLDVTESGATISKNYDLSDLPGPPSKPQVTDVTKNSVTLSWQPGTP-GTLPASAYIIEAF 560
Query: 1105 ADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSD 1149
+ + W TV H + T V L Y F V + N G SD
Sbjct: 561 SQSVSNSWQTVANHVKTTLYTVRGLRPNTIYLFMVRAINPQGLSD 605
Score = 37.0 bits (84), Expect = 0.12
Identities = 28/79 (35%), Positives = 33/79 (41%), Gaps = 9/79 (11%)
Query: 1192 VIAGYTAMLCCAVRGSPKPKISWFKNG----LDLGEDARFRMFSKQGVL----TLEIRKP 1243
V G L C G P P I W+K+G D + RM G L + R+
Sbjct: 42 VSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRS 101
Query: 1244 CPFDGGIYVCRATNLQGEA 1262
P D G YVC A N GEA
Sbjct: 102 KP-DEGSYVCVARNYLGEA 119
>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3874
Score = 108 bits (269), Expect = 4e-23
Identities = 213/921 (23%), Positives = 333/921 (36%), Gaps = 172/921 (18%)
Query: 394 VKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCSTE----LFV 449
+ WL+NG S + E + L +S +AD A+Y CV + S E L V
Sbjct: 1686 ISWLQNGLPFSPSPRLQVLED---GQVLQVSTAEVADAASYMCVAENQAGSAEKLFTLRV 1742
Query: 450 KEPPVLITRPLEDQLVMVGQRVEFECEV-SEEGAQVKWLKDGVELTREETFKYRFKKDGQ 508
+ PP + LE ++ V C+V + +V W KD L+ E F G
Sbjct: 1743 QVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEV---FLLPGT 1799
Query: 509 RHHLIINEAMLEDAGHY---ALCTSG-GQALAEL--IVQEKKLEVYQSIAD-LMVGAKDQ 561
H L + A L D+G Y AL +G Q L +L +V + + D ++V D+
Sbjct: 1800 -HTLQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRVGDK 1858
Query: 562 AVFKCEVSDENVRGV-WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEG 620
AV CE V W K+G+ LV R + G+ +L I + +D+ YS
Sbjct: 1859 AVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQ--RLEIQEAQVSDKGLYSCKVSN 1916
Query: 621 FACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPT 680
A + + + P E PK +T+ VAG+ L L +SG PAPT
Sbjct: 1917 VA---GEAVRTFTLTVQVPPTFENPKT---------ETVSQVAGSPLVLTCDVSGVPAPT 1964
Query: 681 VIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEG 740
V W K R+ VE++ + + G
Sbjct: 1965 VTWLK-------------------------------------DRMPVESSAVHGVVSRGG 1987
Query: 741 ------AEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEP 794
+ G YT +N E + + V V+ AP+I + G V E
Sbjct: 1988 RLQLSRLQPAQAGTYTCVAENTQAEARKDFVVAVL------VAPRIRSSG-----VAREH 2036
Query: 795 PAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEG---VVYEMRVYAVNA 851
+G + L + + W++ L Q++ R ++G V+ +R A
Sbjct: 2037 HVLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGA 2096
Query: 852 IGMSRPSPASQP--FMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYC 909
+PA + + PT D S T VS RP E V C
Sbjct: 2097 YTCVAHNPAGEDARLHTVNVLVPPTIKQGADGSGTLVS---RPGELV---------TMVC 2144
Query: 910 PEGCSEWVAALQGLTEHTSILVKDLPT---------GARLLFRVRAHNMAGPGA-PVTTT 959
P S + H S L LP G+ R+ +A G
Sbjct: 2145 PVRGSPPI--------HVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAA 2196
Query: 960 EPVTVQE-----ILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPL 1014
P V + +Q P + P + + G V L +G P P V+W K+G+PL
Sbjct: 2197 SPAGVADRNFTLQVQVPPVLEPVEFQNDVVVVRGSLVELPCEARGVPLPLVSWMKDGEPL 2256
Query: 1015 AGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKP-----SPP 1069
+ S+ P+ L + A SGTY E E + L V++ P P
Sbjct: 2257 LSQ--SLEQGPS---LQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEPPHIEDSGQP 2311
Query: 1070 QDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPEL 1129
+L +T + + + + T W K + T LE+ R V L
Sbjct: 2312 TELSLTPGAPMELLCDAQGTPQPNIT--W--------HKDGQALTRLENNSRATRV---L 2358
Query: 1130 IIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVN 1189
+ + + +++ G +++ + PPN P F L
Sbjct: 2359 RVRDAGLYTCLAESPAGAIEKSFRVR----------VQAPPNIVG---PRGPRFVVGLAP 2405
Query: 1190 RSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGG 1249
++ L C+V P PKI+W ++G+ L EDA F ++G L+++ D G
Sbjct: 2406 GQLV------LECSVEAEPAPKITWHRDGIVLQEDAH-TQFPERGRF-LQLQALSTADSG 2457
Query: 1250 IYVCRATNLQGEARCECRLEV 1270
Y C A N G R+E+
Sbjct: 2458 DYSCTARNAAGSTSVAFRVEI 2478
Score = 89.0 bits (219), Expect = 3e-17
Identities = 211/925 (22%), Positives = 323/925 (34%), Gaps = 163/925 (17%)
Query: 388 ADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQC----VVGGEKC 443
A + EV W K+ Q + + ++ + TL + + L+D Y C G ++
Sbjct: 1772 AHPNPEVTWYKDSQALSLGEEVFL---LPGTHTLQLGRARLSDSGMYTCEALNAAGRDQK 1828
Query: 444 STELFVKEPPVLITRPLEDQ---LVMVGQRVEFECEVSE-EGAQVKWLKDGVELTREETF 499
+L V PP P Q LV VG + CE V W KDG L +
Sbjct: 1829 LVQLSVLVPPAFRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQ-- 1886
Query: 500 KYRFKKDGQRHHLIINEAMLEDAGHYALCTSG--GQALAELIVQEKKLEVYQSIADLMVG 557
+ + + GQR L I EA + D G Y+ S G+A+ + + +++ V
Sbjct: 1887 RTQALRGGQR--LEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKTETVS 1944
Query: 558 --AKDQAVFKCEVSDENVRGV-WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADY 614
A V C+VS V WLK+ + +S + R +L + + PA Y
Sbjct: 1945 QVAGSPLVLTCDVSGVPAPTVTWLKD--RMPVESSAVHGVVSRGGRLQLSRLQPAQAGTY 2002
Query: 615 SFVPEGFACNLSAKLHFMEVKIDFVPRQ-EPPKIHLDCPGRIPDTIVVVAGNKLRLDVPI 673
+ V E N A E + DFV P+I R V+ G ++RLD
Sbjct: 2003 TCVAE----NTQA-----EARKDFVVAVLVAPRIRSSGVAREHH---VLEGQEVRLDCEA 2050
Query: 674 SGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDR 733
G P P V W K +D G + D L
Sbjct: 2051 DGQPPPDVAWLK-----------DGSPLGQDMGPHLRFYLDGGSL--------------- 2084
Query: 734 SIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAP-----AAPKISNVGE--- 785
++G D G YT NP GED TV V+ P + +S GE
Sbjct: 2085 ---VLKGLRASDAGAYTCVAHNPAGEDARLHTVNVLVPPTIKQGADGSGTLVSRPGELVT 2141
Query: 786 DSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMR 845
C V+ PP + W++ L LS R ++ G + +R
Sbjct: 2142 MVCPVRGSPPIH------------------VSWLKDGLPL--PLSQ--RTLLHGSGHTLR 2179
Query: 846 VYAV--------NAIGMSRPSPASQPF---MPIGPPSEPTHLAVEDVSDTTVSLKWRPPE 894
+ V + S A + F + + P EP DV SL P E
Sbjct: 2180 ISKVQLADAGIFTCVAASPAGVADRNFTLQVQVPPVLEPVEFQ-NDVVVVRGSLVELPCE 2238
Query: 895 RVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGA 954
A G+ V + +G Q L + S+ ++ + G + A + AG
Sbjct: 2239 ---ARGVPLPLVSWMKDG---EPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEAR 2292
Query: 955 ---PVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEG 1011
+T EP +++ Q L L G P+ LL QG P+P +TW K+G
Sbjct: 2293 RHFQLTVMEPPHIEDSGQPTELSL----------TPGAPMELLCDAQGTPQPNITWHKDG 2342
Query: 1012 QPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQD 1071
Q L E NS +L +R A G Y + + ++V +PP
Sbjct: 2343 QALTRLE---NNSRATRVLRVRDA-----GLYTCLAESPAGAIEKSFRVRV---QAPP-- 2389
Query: 1072 LRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWF---TVLEHYRRTHCVVPE 1128
+ G + P Q V +V+ + W VL+ H PE
Sbjct: 2390 -NIVGPRGPRFVVGLAPGQLVLEC-----SVEAEPAPKITWHRDGIVLQ--EDAHTQFPE 2441
Query: 1129 LIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLV 1188
G + ++ + + D + T + + + + P V
Sbjct: 2442 ----RGRFLQLQALSTADSGDYSCTARNAA--GSTSVAFRVEIHTVPTIRSGPPAVNVSV 2495
Query: 1189 NRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDG 1248
N++ + L C G P P +SW K+ + L D R F +L I+ D
Sbjct: 2496 NQTAL------LPCQADGVPAPLVSWRKDRVPL--DPRSPRFEILPEGSLRIQPVLAQDA 2547
Query: 1249 GIYVCRATNLQGEARCECRLEVRVP 1273
G Y+C A+N G R L V P
Sbjct: 2548 GHYLCLASNSAGSDRQGRDLRVLEP 2572
Score = 72.0 bits (175), Expect = 3e-12
Identities = 306/1379 (22%), Positives = 459/1379 (33%), Gaps = 311/1379 (22%)
Query: 11 AFSKKPR----SVEVAAGSPAVFEAETERAGVK-VRWQRGGSDISASNKYGLATEGTRHT 65
AF + PR +V V G AV ET+ V W + G + + + G R
Sbjct: 1839 AFRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQR-- 1896
Query: 66 LTVREVGPADQGSYAV----IAGSSKVKFDLKV-----IEAEKAEPMLAPAPAPAEATGA 116
L ++E +D+G Y+ +AG + F L V E K E + A +P T
Sbjct: 1897 LEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCD 1956
Query: 117 PGEAPAPAA------------------------ELGESAPSPKGSSSAALNGPTPGAPDD 152
PAP +L P+ G+ + A D
Sbjct: 1957 VSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAENTQAEARKD 2016
Query: 153 PIGLFVMRPQ--------DGEVTVGGSITFSARVAGASLLKPPVVKWFKGKWVDLSSKVG 204
+ ++ P+ + V G + G PP V W K L +G
Sbjct: 2017 FVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQP---PPDVAWLKDG-SPLGQDMG 2072
Query: 205 QHLQLHDSYDRASKVYLFELHITDAQPAFTGSYRCEVSTKDKFDCSNFNLTV-------H 257
HL+ Y + L L +DA G+Y C D + V
Sbjct: 2073 PHLRF---YLDGGSLVLKGLRASDA-----GAYTCVAHNPAGEDARLHTVNVLVPPTIKQ 2124
Query: 258 EAMGTGDLDLLSAFRRTSLAG--GGRRISDSHEDTGI-LDFSSLLKKRDSFRTPRDSKLE 314
A G+G L T + G I S G+ L S S T R SK++
Sbjct: 2125 GADGSGTLVSRPGELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQ 2184
Query: 315 APAEEDVWEILRQAP--------------PSEYERIAFQYGVTDLRGMLKRLKGMRRDEK 360
A+ ++ + +P P E + FQ V +RG L L R
Sbjct: 2185 L-ADAGIFTCVAASPAGVADRNFTLQVQVPPVLEPVEFQNDVVVVRGSLVELPCEAR--- 2240
Query: 361 KSTAFQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRT 420
G + L V W+K+G+ + + +S+ +
Sbjct: 2241 -----------------GVPLPL----------VSWMKDGEPL-------LSQSLEQGPS 2266
Query: 421 LTISQCSLADDAAYQCVV----GGEKCSTELFVKEPPVLITRPLEDQLVMV-GQRVEFEC 475
L + D Y CV G + +L V EPP + +L + G +E C
Sbjct: 2267 LQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEPPHIEDSGQPTELSLTPGAPMELLC 2326
Query: 476 EVS-EEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQA 534
+ + W KDG LTR E + R ++ + DAG Y C + A
Sbjct: 2327 DAQGTPQPNITWHKDGQALTRLE--------NNSRATRVLR---VRDAGLYT-CLAESPA 2374
Query: 535 LAELIVQEKKLEVYQSIADLMVG----------AKDQAVFKCEVSDENVRGV-WLKNGKE 583
A EK V +VG A Q V +C V E + W ++G
Sbjct: 2375 GAI----EKSFRVRVQAPPNIVGPRGPRFVVGLAPGQLVLECSVEAEPAPKITWHRDGIV 2430
Query: 584 LVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVP--R 641
L D+ + GR L + ++ AD DYS A + S V+I VP R
Sbjct: 2431 LQEDAHTQFPERGRF--LQLQALSTADSGDYSCTARNAAGSTSVAFR---VEIHTVPTIR 2485
Query: 642 QEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDA 701
PP ++ V L G PAP V W+K ++ P P
Sbjct: 2486 SGPPAVN------------VSVNQTALLPCQADGVPAPLVSWRK-----DRVPLDPRSPR 2528
Query: 702 PEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQ 761
E EG +R++ +D G Y N G D+
Sbjct: 2529 FEIL---------------PEGSLRIQPVL-----------AQDAGHYLCLASNSAGSDR 2562
Query: 762 VNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGG-QPIL-----GYILE-RKKKK 814
++V++ P AP SN+ + T P G +P++ G L+ R ++
Sbjct: 2563 QGRDLRVLEPP--AIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQG 2620
Query: 815 SYRWMRLNFDLIQELSHEARRMIEGVV----------YEMRVYAVNAIGMSRPSPASQPF 864
+YR + N L+ + E VV Y++ V+ I +
Sbjct: 2621 AYRLLPSNALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVHVPPTIADDQTDFTVTMM 2680
Query: 865 MPIGPPSEPTHLAVEDVSDTTVSLKW-RPPERVGAGGLDGYSVEYCPEGCSEWVAALQGL 923
P+ T + VS W + ++GA G GY V P G E
Sbjct: 2681 APVVLTCHSTGIPAPTVS-------WSKAGAQLGARG-SGYRVS--PSGALE-------- 2722
Query: 924 TEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTI 983
+ + LP A + A N AG +TVQ + + L +
Sbjct: 2723 ------IGQALPIHAGR-YTCSARNSAGVAHKHVF---LTVQAS------PVVKPLPSVV 2766
Query: 984 QKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTY 1043
+ E V L G PRP +TW KEG +A VS + P + A+ +G Y
Sbjct: 2767 RAVAEEEVLLPCEASGIPRPTITWQKEGLNVA-TGVSTQVLPGGQLRIAHASPE-DAGNY 2824
Query: 1044 QVTVRIE--NMEDKATLVLQV---VDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELW 1098
+ + K LV+QV ++ P DL T+ G + L K W
Sbjct: 2825 LCIAKNSAGSAMGKTRLVVQVPPVIENGLP--DLSTTE--GSHAFLPCKARGSPEPNITW 2880
Query: 1099 ---GYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTK 1155
G V A+ K FT+ +V L + + ++N VG + R
Sbjct: 2881 DKDGQPVSGAEGK----FTIQPS---GELLVKNLEGQDAGTYTCTAENAVGRARRRVHLT 2933
Query: 1156 E---PVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKI 1212
PVF PG +RS+ G L CA RGSP P+I
Sbjct: 2934 ILVLPVFTTLPG------------------------DRSLRLGDRLWLRCAARGSPTPRI 2969
Query: 1213 SWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVR 1271
W N + E + + G TL+ D G YVC A N G + + V+
Sbjct: 2970 GWTVNDRPVTEG----VSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVK 3024
Score = 67.8 bits (164), Expect = 6e-11
Identities = 194/963 (20%), Positives = 324/963 (33%), Gaps = 175/963 (18%)
Query: 375 VSKGHKIRLTVE-LADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAA 433
V+ + I L E LA + W+K+G + S + + + L I D
Sbjct: 1362 VTVNNPISLICEALAFPSPNITWMKDGAPFEASRN---IQLLPGTHGLQILNAQKEDAGQ 1418
Query: 434 YQCVVGGE------KCSTELFVKEPPVLITRPL-----EDQLVMVGQRVEFECEV-SEEG 481
Y CVV E E+ + P + PL ++ V + ECE +
Sbjct: 1419 YTCVVTNELGEAVKNYHVEVLIP-PSISKDDPLGEVGVKEVKTKVNSTLTLECESWAVPP 1477
Query: 482 AQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTS---GGQALAEL 538
++W KDG +T R + G+ L I + D+G Y LC + G+ +
Sbjct: 1478 PTIRWYKDGQPVTPSS----RLQVLGEGRLLQIQPTQVSDSGRY-LCVATNVAGEDDQDF 1532
Query: 539 IVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDENVRG----------------------- 575
V + ++Q + D A F+ +E RG
Sbjct: 1533 NVLIQVPPMFQKVGDF------SAAFEILSREEEARGGVTEYREIVENNPAYLYCDTNAI 1586
Query: 576 -----VWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLH 630
W + + L + V GRV L I V + YS C S ++
Sbjct: 1587 PPPDLTWYREDQPLSAGDEVSVLQGGRV--LQIPLVRAENAGRYS-------CKASNEVG 1637
Query: 631 FMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQG 690
E + + P + L + + + V A + + L P G+P PT+ W +
Sbjct: 1638 --EDWLHYELLVLTPPVILGDTEELVEEVTVNASSTVSLQCPALGNPVPTISWLQ----- 1690
Query: 691 NKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYT 750
N P P+P R++ +D + V AE D Y
Sbjct: 1691 NGLPFSPSP--------------------------RLQVLEDGQVLQVSTAEVADAASYM 1724
Query: 751 VTVKNPVGEDQVNLTVKVIDVPDAPAA---PKISNVGEDSCTVQWEPPAYDGGQPILGYI 807
+N G + T++V VP A +++ + S ++ + A+ + + Y
Sbjct: 1725 CVAENQAGSAEKLFTLRV-QVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPE-VTWY- 1781
Query: 808 LERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPI 867
K + + L ++ ++ + + +Y A+ + +
Sbjct: 1782 ------KDSQALSLGEEVFLLPGTHTLQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVL 1835
Query: 868 GPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEW---------VA 918
PP+ A D + RVG + + PE W
Sbjct: 1836 VPPA--FRQAPRGPQDAVL-------VRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQ 1886
Query: 919 ALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRH 978
Q L + +++ + L+ + N+AG A T T V V + P+
Sbjct: 1887 RTQALRGGQRLEIQEAQVSDKGLYSCKVSNVAGE-AVRTFTLTVQVPPTFENPK------ 1939
Query: 979 LRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRV 1038
+T+ + G P+ L G P P VTW K+ P+ V S + R +
Sbjct: 1940 -TETVSQVAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSR-LQPA 1997
Query: 1039 HSGTYQVTVRIENMEDKATLVLQVVDKP-----SPPQDLRVTDAW--GLNVALEWKPPQD 1091
+GTY E + V+ V+ P ++ V + L+ + +PP D
Sbjct: 1998 QAGTYTCVAENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPPD 2057
Query: 1092 VGNTELWGYTVQKADKKTMEWFTVLEHY-RRTHCVVPELIIGNGYYFRVFSQNMVGFSDR 1150
V W ++ + L Y V+ L + + + N G R
Sbjct: 2058 VA----W---LKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAGEDAR 2110
Query: 1151 AATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKP 1210
T V PP K + + LV+R G + C VRGSP
Sbjct: 2111 LHTVNVLV----------PPTIK-----QGADGSGTLVSR---PGELVTMVCPVRGSPPI 2152
Query: 1211 KISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
+SW K+GL L R + TL I K D GI+ C A + G A L+V
Sbjct: 2153 HVSWLKDGLPLPLSQRTLLHGSGH--TLRISKVQLADAGIFTCVAASPAGVADRNFTLQV 2210
Query: 1271 RVP 1273
+VP
Sbjct: 2211 QVP 2213
Score = 67.4 bits (163), Expect = 8e-11
Identities = 199/929 (21%), Positives = 320/929 (34%), Gaps = 136/929 (14%)
Query: 370 EPAYQVSKGHKIRLTVEL-ADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSL 428
+ A V G K L+ E A + V W K+GQ + ++ +++ + L I + +
Sbjct: 1848 QDAVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQRT---QALRGGQRLEIQEAQV 1904
Query: 429 ADDAAYQCVVG---GEKCST-ELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQ- 483
+D Y C V GE T L V+ PP E + G + C+VS A
Sbjct: 1905 SDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCDVSGVPAPT 1964
Query: 484 VKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAE-----L 538
V WLKD + + E + + G R L ++ AG Y QA A
Sbjct: 1965 VTWLKDRMPV--ESSAVHGVVSRGGR--LQLSRLQPAQAGTYTCVAENTQAEARKDFVVA 2020
Query: 539 IVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDENVRGV-WLKNGKELVPDSRIKVSHIGR 597
++ ++ + V + CE + V WLK+G L D +
Sbjct: 2021 VLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLD 2080
Query: 598 VHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPD 657
L + + +D Y+ V A A+LH + V + PP I G
Sbjct: 2081 GGSLVLKGLRASDAGAYTCVAHNPAGE-DARLHTVNVLV-------PPTIKQGADGS--G 2130
Query: 658 TIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKL 717
T+V G + + P+ G P V W K P P ++
Sbjct: 2131 TLVSRPGELVTMVCPVRGSPPIHVSWLK--------DGLPLP-------------LSQRT 2169
Query: 718 LCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAA 777
L G + + D G++T +P G N T++V VP
Sbjct: 2170 LLHGSGHT----------LRISKVQLADAGIFTCVAASPAGVADRNFTLQV-QVPPVLEP 2218
Query: 778 PKISNVGEDSCTVQW---EPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEAR 834
+ N D V+ E P G P+ WM+ L+ + +
Sbjct: 2219 VEFQN---DVVVVRGSLVELPCEARGVPL----------PLVSWMKDGEPLLSQSLEQGP 2265
Query: 835 RMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPE 894
+ V + + +S A + F EP H+ + T +SL P
Sbjct: 2266 SLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLT--VMEPPHIE-DSGQPTELSLTPGAPM 2322
Query: 895 RVGAGGLDGYSVEYCPEGCSEWVAALQGLT--EHTSILVKDLPTGARLLFRVRAHNMAGP 952
+ + P+ W Q LT E+ S + L L+ A + AG
Sbjct: 2323 ELLC------DAQGTPQPNITWHKDGQALTRLENNSRATRVLRVRDAGLYTCLAESPAGA 2376
Query: 953 GAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQ 1012
+ + V VQ P + PR R + G+ V L + +P P++TW ++G
Sbjct: 2377 ---IEKSFRVRVQA---PPNIVGPRGPRFVVGLAPGQLV-LECSVEAEPAPKITWHRDGI 2429
Query: 1013 PLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPS----- 1067
L E+ + L ++A SG Y T R +++ P+
Sbjct: 2430 VLQ-EDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGSTSVAFRVEIHTVPTIRSGP 2488
Query: 1068 PPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVP 1127
P ++ V L + P V W D ++ + + E R + P
Sbjct: 2489 PAVNVSVNQTALLPCQADGVPAPLVS----WRKDRVPLDPRSPRFEILPEGSLR---IQP 2541
Query: 1128 ELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPL 1187
L G+Y + S N G SDR + L E P+
Sbjct: 2542 VLAQDAGHYLCLAS-NSAG-SDRQG--------------------RDLRVLEPPAIAPSP 2579
Query: 1188 VNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLG---EDARFRMFSKQGVLTLEIRKPC 1244
N ++ A A+L C GSPKP + W+K+G L + +R+ +L + P
Sbjct: 2580 SNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNALL---LTAPG 2636
Query: 1245 PFDGGIYVCRATNLQGEARCECRLEVRVP 1273
P D + C +N GEA ++ V VP
Sbjct: 2637 PQDSAQFECVVSNEVGEAHRLYQVTVHVP 2665
Score = 65.9 bits (159), Expect = 2e-10
Identities = 208/899 (23%), Positives = 317/899 (35%), Gaps = 156/899 (17%)
Query: 394 VKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVV----GGEKCSTELFV 449
+ W K+GQ + + + A R L + L Y C+ G + S + V
Sbjct: 2336 ITWHKDGQALTR-----LENNSRATRVLRVRDAGL-----YTCLAESPAGAIEKSFRVRV 2385
Query: 450 KEPPVLITRPLEDQLVM---VGQRVEFECEVSEEGA-QVKWLKDGVELTREETFKYRFKK 505
+ PP ++ P + V+ GQ V EC V E A ++ W +DG+ L +E +F +
Sbjct: 2386 QAPPNIVG-PRGPRFVVGLAPGQLV-LECSVEAEPAPKITWHRDGIVL--QEDAHTQFPE 2441
Query: 506 DGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIAD----LMVGAKDQ 561
G+ L + D+G Y+ CT+ A + + ++ +I + V
Sbjct: 2442 RGR--FLQLQALSTADSGDYS-CTARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQT 2498
Query: 562 AVFKCEVSDENVRGV-WLKNGKELVPDS-RIKVSHIGRVHKLTIDDVTPADEADYSFVPE 619
A+ C+ V W K+ L P S R ++ G L I V D Y +
Sbjct: 2499 ALLPCQADGVPAPLVSWRKDRVPLDPRSPRFEILPEG---SLRIQPVLAQDAGHYLCLAS 2555
Query: 620 GFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAP 679
A + ++++ EPP I P + + A L SG P P
Sbjct: 2556 NSA---GSDRQGRDLRV-----LEPPAI-----APSPSNLTLTAHTPALLPCEASGSPKP 2602
Query: 680 TVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIF--T 737
V+W K G K R A +LL + +D + F
Sbjct: 2603 LVVWWK---DGQKLDFRLQQGA-------------YRLLPSNALLLTAPGPQDSAQFECV 2646
Query: 738 VEGAEKEDEGVYTVTVKNP--VGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPP 795
V E +Y VTV P + +DQ + TV ++ AP + G + TV W
Sbjct: 2647 VSNEVGEAHRLYQVTVHVPPTIADDQTDFTVTMM----APVVLTCHSTGIPAPTVSWSKA 2702
Query: 796 AYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMI------EGVVYEMRVYAV 849
G GY + ++ Q L A R GV ++ V
Sbjct: 2703 GAQLGARGSGYRVSPSGA---------LEIGQALPIHAGRYTCSARNSAGVAHKHVFLTV 2753
Query: 850 NAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYC 909
A + +P P+ + E L E ++ W ++ G G S +
Sbjct: 2754 QASPVVKPLPS----VVRAVAEEEVLLPCEASGIPRPTITW---QKEGLNVATGVSTQVL 2806
Query: 910 PEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQ 969
P G Q H S P A + A N AG A T V V +++
Sbjct: 2807 PGG--------QLRIAHAS------PEDAGNYLCI-AKNSAG-SAMGKTRLVVQVPPVIE 2850
Query: 970 RPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTI 1029
LP + G L +G P P +TW K+GQP++G E P+ +
Sbjct: 2851 NG---LP-----DLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGEL 2902
Query: 1030 LFIRAARRVHSGTYQVTV-----RIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVAL 1084
L ++ +GTY T R LVL V + LR+ D L A
Sbjct: 2903 L-VKNLEGQDAGTYTCTAENAVGRARRRVHLTILVLPVFTTLPGDRSLRLGDRLWLRCAA 2961
Query: 1085 EWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNM 1144
P T G+TV D+ E V E + + + + +++N
Sbjct: 2962 RGSP------TPRIGWTVN--DRPVTE--GVSEQDGGSTLQRAAVSREDSGTYVCWAENR 3011
Query: 1145 VGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAV 1204
VG T+ F+ E P + FS +P+ G + L C V
Sbjct: 3012 VG------RTQAVSFVH----VKEAPVLQGEAFS---YLVEPV-------GGSIQLDCVV 3051
Query: 1205 RGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEAR 1263
RG P P I W K+GL L + R + G LT I + D G Y C A N G A+
Sbjct: 3052 RGDPVPDIHWIKDGLPL-RGSHLRHQLQNGSLT--IHRTERDDAGRYQCLAENEMGVAK 3107
Score = 65.1 bits (157), Expect = 4e-10
Identities = 80/318 (25%), Positives = 121/318 (38%), Gaps = 59/318 (18%)
Query: 976 PRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRN-SPTDTILFIRA 1034
P T+ + G P +L +G P P+++W K+GQPL GE +++ S +L++
Sbjct: 974 PLRESHTLTVREGHPTSLSCECRGVPFPKISWRKDGQPLPGEGAGLQHVSAVGRLLYLGQ 1033
Query: 1035 ARRVHSGTYQ------VTVRIENMEDKATLVLQVVDKPSPPQDLRVTD--AWGLNVALEW 1086
A+ GTY V ++++ + + Q+ PP + V L
Sbjct: 1034 AQLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQIAGPREPPTQVSVVQDGVATLECNATG 1093
Query: 1087 KPP---------QDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYF 1137
KPP Q VG EL G +Q + H R CV
Sbjct: 1094 KPPPTVTWERDGQPVG-AEL-GLQLQNQGQSLHVERAQAAHTGRYSCV------------ 1139
Query: 1138 RVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYT 1197
++N+ G ++R V +P P LD PL N +
Sbjct: 1140 ---AENLAGRAERKFELS--VLVP-------PELIGDLD---------PLTNITAALHSP 1178
Query: 1198 AMLCCAVRGSPKPKISWFK--NGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRA 1255
L C G P P I WF+ + GED + G L++ + D G+Y C A
Sbjct: 1179 LTLLCEAMGIPPPAIRWFRGEEPVSPGEDT----YLLAGGWMLKMTQTQEQDSGLYSCLA 1234
Query: 1256 TNLQGEARCECRLEVRVP 1273
+N GEAR +EV VP
Sbjct: 1235 SNEAGEARRNFSVEVLVP 1252
Score = 64.7 bits (156), Expect = 5e-10
Identities = 92/348 (26%), Positives = 135/348 (38%), Gaps = 62/348 (17%)
Query: 942 FRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKP 1001
+R A N+AG +TE + PR+ LP L + V PV L G P
Sbjct: 763 YRCVASNVAG------STELRYGLRVNVPPRITLPPSLPGPVL--VNTPVRLTCNATGAP 814
Query: 1002 RPQVTWTKEGQPLAGEEV-SIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVL 1060
P + W K+G P++ ++ P +L + +AR SG Y ED+ +VL
Sbjct: 815 SPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVL 874
Query: 1061 QVVDKPSP-PQDLRVTDAWGLNVALEWK-----PP-----QDVGNTELWGYTVQKADKKT 1109
QV PS ++L V+ +VALE + PP +D E ADK
Sbjct: 875 QVHMPPSILGEELNVSVVANESVALECQSHAMPPPVLSWWKDGRPLEPRPGVHLSADKAL 934
Query: 1110 MEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTK---EPVFIPRPGIT 1166
++ V + + ++ + N G S++ PVF R T
Sbjct: 935 LQ--------------VDRADVWDAGHYTCEALNQAGRSEKHYNLNVWVAPVFPLRESHT 980
Query: 1167 YEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDL-GEDA 1225
+V G+ L C RG P PKISW K+G L GE A
Sbjct: 981 L-----------------------TVREGHPTSLSCECRGVPFPKISWRKDGQPLPGEGA 1017
Query: 1226 RFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVRVP 1273
+ S G L L + + G Y C +N+ G + + +LEV VP
Sbjct: 1018 GLQHVSAVGRL-LYLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVP 1064
Score = 56.6 bits (135), Expect = 1e-07
Identities = 146/685 (21%), Positives = 240/685 (35%), Gaps = 120/685 (17%)
Query: 393 EVKWLKNGQEIQMSGSKYIFESIGAK-RTLTISQCSLADDAAYQCVVGGEKCSTE----L 447
+V W K Q + S ++ ++ R L I Q L+D +Y+CV STE L
Sbjct: 725 DVSWFKGHQPV----SSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASNVAGSTELRYGL 780
Query: 448 FVKEPPVLITRPLEDQLVMVGQRVEFECEVS-EEGAQVKWLKDGVELTREETFKYRFKKD 506
V PP + P V+V V C + + WLKDG ++ T +
Sbjct: 781 RVNVPPRITLPPSLPGPVLVNTPVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPG 840
Query: 507 GQRHHLIINEAMLEDAGHYA--LCTSGGQALAELIVQ-EKKLEVYQSIADLMVGAKDQAV 563
G+ L + A D+G Y+ ++ G+ ++++Q + ++ V A +
Sbjct: 841 GR--VLTLASARASDSGRYSCVAVSAVGEDRQDVVLQVHMPPSILGEELNVSVVANESVA 898
Query: 564 FKCEVSDENVRGV--WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGF 621
+C+ S V W K+G+ L P + +S + L +D D Y+
Sbjct: 899 LECQ-SHAMPPPVLSWWKDGRPLEPRPGVHLSADKAL--LQVDRADVWDAGHYTCEALNQ 955
Query: 622 ACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTV 681
A S K + + V + V P R T+ V G+ L G P P +
Sbjct: 956 A-GRSEKHYNLNVWVAPV-----------FPLRESHTLTVREGHPTSLSCECRGVPFPKI 1003
Query: 682 IWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGA 741
W+K +P P EG + + + A
Sbjct: 1004 SWRK--------DGQPLPG---------------------EGAGLQHVSAVGRLLYLGQA 1034
Query: 742 EKEDEGVYTVTVKNPVGEDQVNLTVKVIDVP----------------DAPAAPKISNVGE 785
+ EG YT N VG +L ++V P D A + + G+
Sbjct: 1035 QLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQIAGPREPPTQVSVVQDGVATLECNATGK 1094
Query: 786 DSCTVQWEPPAYDGGQPI---LGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVY 842
TV WE GQP+ LG L+ + + L+ + Q +H R
Sbjct: 1095 PPPTVTWE----RDGQPVGAELGLQLQNQGQS------LHVERAQ-AAHTGRYSCVAENL 1143
Query: 843 EMRVYAVNAIGMSRPSPASQPFMPI----GPPSEPTHLAVEDVSDTTVSLKWRPPERVGA 898
R + + P P+ P L E + +++W E +
Sbjct: 1144 AGRAERKFELSVLVPPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWFRGEEPVS 1203
Query: 899 GGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTT 958
G D Y + W+ + E S L L A N AG +
Sbjct: 1204 PGEDTYLL------AGGWMLKMTQTQEQDSGLYSCL-----------ASNEAGEARRNFS 1246
Query: 959 TEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEE 1018
E+L P ++ L + I+ G+ +L+ G P+P++TW K+G+PLA +
Sbjct: 1247 V------EVLVPPSIE-NEDLEEVIKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGD 1299
Query: 1019 VSIRNSPTDTILFIRAARRVHSGTY 1043
SP +L + A +G Y
Sbjct: 1300 AH-HISPDGVLLQVLQANLSSAGHY 1323
Score = 55.5 bits (132), Expect = 3e-07
Identities = 74/303 (24%), Positives = 109/303 (35%), Gaps = 41/303 (13%)
Query: 981 QTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHS 1040
Q + G V L G P PQV WTK+ QP+ ++ +L I +
Sbjct: 225 QEVLGLAGADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHVGDE 284
Query: 1041 GTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGY 1100
G YQ + L+V P+ WG N E +D L
Sbjct: 285 GRYQCVAFSPAGQQARDFQLRVHAPPT---------IWGSNETGEVAVMEDHLVQLLC-- 333
Query: 1101 TVQKADKKTMEWFTVLEHYRRTHCVV-----PELIIGNGY-----YFRVFSQNMVGFSDR 1150
+ + WF + VV +L +G + + N VG +++
Sbjct: 334 EARGVPTPNITWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGAAEK 393
Query: 1151 AATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKP 1210
A Y PP + +P V ++V AG L C RG P P
Sbjct: 394 ATRLD----------VYVPPTIEGAG-------GRPYVVKAV-AGRPVALECVARGHPSP 435
Query: 1211 KISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
+SW GL + E R+ + VL LE P G+Y C A++ GEA + +EV
Sbjct: 436 TLSWHHEGLPVAESNESRLETDGSVLRLE--SPGEASSGLYSCVASSPAGEAVLQYSVEV 493
Query: 1271 RVP 1273
+VP
Sbjct: 494 QVP 496
Score = 48.9 bits (115), Expect = 3e-05
Identities = 91/436 (20%), Positives = 151/436 (34%), Gaps = 76/436 (17%)
Query: 369 LEPAYQVSKGHKIRLTVELADH-DAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCS 427
LE +V G L + H ++ W K+G+ + + +I L + Q +
Sbjct: 1260 LEEVIKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHHISPD---GVLLQVLQAN 1316
Query: 428 LADDAAYQCVVG---GEKCST-ELFVKEPPVLI----TRPLEDQLVMVGQRVEFECE-VS 478
L+ Y C+ GEK +L V P ++ E+ V V + CE ++
Sbjct: 1317 LSSAGHYSCIAANAVGEKTKHFQLSVLLAPTILGGAEDSADEEVTVTVNNPISLICEALA 1376
Query: 479 EEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSG--GQALA 536
+ W+KDG + H L I A EDAG Y + G+A+
Sbjct: 1377 FPSPNITWMKDGAPFEASRNIQLL----PGTHGLQILNAQKEDAGQYTCVVTNELGEAVK 1432
Query: 537 ELIVQ----------EKKLEVYQSIADLMVGAKDQAVFKCE---VSDENVRGVWLKNGKE 583
V+ + EV + ++ +CE V +R W K+G+
Sbjct: 1433 NYHVEVLIPPSISKDDPLGEV--GVKEVKTKVNSTLTLECESWAVPPPTIR--WYKDGQP 1488
Query: 584 LVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFA------CNLSAKLHFMEVKI- 636
+ P SR++V GR+ L I +D Y V A N+ ++ M K+
Sbjct: 1489 VTPSSRLQVLGEGRL--LQIQPTQVSDSGRYLCVATNVAGEDDQDFNVLIQVPPMFQKVG 1546
Query: 637 DFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPAR 696
DF E + G + + +V N L + P P + W +
Sbjct: 1547 DFSAAFEILSREEEARGGVTEYREIVENNPAYLYCDTNAIPPPDLTWYR----------- 1595
Query: 697 PAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNP 756
D P GD V + + + E+ G Y+ N
Sbjct: 1596 --EDQPLSAGD------------------EVSVLQGGRVLQIPLVRAENAGRYSCKASNE 1635
Query: 757 VGEDQVNLTVKVIDVP 772
VGED ++ + V+ P
Sbjct: 1636 VGEDWLHYELLVLTPP 1651
Score = 46.6 bits (109), Expect = 2e-04
Identities = 32/80 (40%), Positives = 41/80 (51%), Gaps = 4/80 (5%)
Query: 1192 VIAGYTAMLCCAVRGSPKPKISWFKNGLDLGE-DARFRMFSKQGVLTLEIRKPCPFDGGI 1250
V+ G TA L C V G P+PK++WFK+G L DA S GVL L++ + G
Sbjct: 1266 VLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHH--ISPDGVL-LQVLQANLSSAGH 1322
Query: 1251 YVCRATNLQGEARCECRLEV 1270
Y C A N GE +L V
Sbjct: 1323 YSCIAANAVGEKTKHFQLSV 1342
Score = 45.8 bits (107), Expect = 3e-04
Identities = 30/93 (32%), Positives = 41/93 (44%), Gaps = 4/93 (4%)
Query: 1181 PSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDL-GEDARFRMFSKQGVLTLE 1239
P L + S G A L C RGSP+P I+W K+G + G + +F + +L
Sbjct: 2847 PVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKN 2906
Query: 1240 IRKPCPFDGGIYVCRATNLQGEARCECRLEVRV 1272
+ D G Y C A N G AR L + V
Sbjct: 2907 LEGQ---DAGTYTCTAENAVGRARRRVHLTILV 2936
Score = 45.1 bits (105), Expect = 4e-04
Identities = 31/88 (35%), Positives = 42/88 (47%), Gaps = 4/88 (4%)
Query: 1186 PLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCP 1245
P V R+V A +L C G P+P I+W K GL++ ++ L I P
Sbjct: 2763 PSVVRAV-AEEEVLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPGG---QLRIAHASP 2818
Query: 1246 FDGGIYVCRATNLQGEARCECRLEVRVP 1273
D G Y+C A N G A + RL V+VP
Sbjct: 2819 EDAGNYLCIAKNSAGSAMGKTRLVVQVP 2846
Score = 42.0 bits (97), Expect = 0.004
Identities = 184/895 (20%), Positives = 291/895 (32%), Gaps = 154/895 (17%)
Query: 421 LTISQCSLADDAAYQC----VVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECE 476
L I + L D+ Y C + G K L V PP + P+ ++ V+ V EC
Sbjct: 659 LQIEKVDLRDEGIYTCAATNLAGESKREVALKVLVPPNIEPGPV-NKAVLENASVTLECL 717
Query: 477 VSE-EGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQAL 535
S V W K ++ DG+ L I +A L DAG Y S
Sbjct: 718 ASGVPPPDVSWFKGHQPVS--SWMGVTVSVDGRV--LRIEQAQLSDAGSYRCVASNVAGS 773
Query: 536 AEL-----IVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSR- 589
EL + ++ + S+ ++ + + +WLK+G + P
Sbjct: 774 TELRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTCNATGAPSPTLMWLKDGNPVSPAGTP 833
Query: 590 -IKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIH 648
++V GRV LT+ +D YS V A E + D V + P
Sbjct: 834 GLQVFPGGRV--LTLASARASDSGRYSCV---------AVSAVGEDRQDVVLQVHMP--- 879
Query: 649 LDCPGRIPD--TIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTG 706
P + + + VVA + L+ P P + W K + P P P
Sbjct: 880 ---PSILGEELNVSVVANESVALECQSHAMPPPVLSWWK-----DGRPLEPRPG------ 925
Query: 707 DSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTV 766
V + D+++ V+ A+ D G YT N G + + +
Sbjct: 926 --------------------VHLSADKALLQVDRADVWDAGHYTCEALNQAGRSEKHYNL 965
Query: 767 KVIDVPDAPAAPKISNVGED------SCTVQWEP-PAYD---GGQPILGYILERKKKKSY 816
V P P + + SC + P P GQP+ G + +
Sbjct: 966 NVWVAPVFPLRESHTLTVREGHPTSLSCECRGVPFPKISWRKDGQPLPGEGAGLQHVSAV 1025
Query: 817 RWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMP---IGPPSEP 873
RL + +L+ E E N +G S + +P GP P
Sbjct: 1026 G--RLLYLGQAQLAQEGTYTCE---------CSNVVGNSSQDLQLEVHVPPQIAGPREPP 1074
Query: 874 THLAV--EDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILV 931
T ++V + V+ + +PP V DG P G LQ + S+ V
Sbjct: 1075 TQVSVVQDGVATLECNATGKPPPTV-TWERDGQ-----PVGAE---LGLQLQNQGQSLHV 1125
Query: 932 KDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPV 991
+ + A N+AG E +L P L I + P+
Sbjct: 1126 ERAQAAHTGRYSCVAENLAG------RAERKFELSVLVPPELIGDLDPLTNITAALHSPL 1179
Query: 992 NLLIPFQGKPRPQVTWTKEGQPLA-GEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIE 1050
LL G P P + W + +P++ GE+ + +L + + SG Y E
Sbjct: 1180 TLLCEAMGIPPPAIRWFRGEEPVSPGEDTYLLAG--GWMLKMTQTQEQDSGLYSCLASNE 1237
Query: 1051 NMEDKATLVLQVVDKPSPPQD-----LRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKA 1105
E + ++V+ PS + ++V D G T V
Sbjct: 1238 AGEARRNFSVEVLVPPSIENEDLEEVIKVLD----------------GQTAHLMCNVTGH 1281
Query: 1106 DKKTMEWFTVLEHYRR--THCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRP 1163
+ + WF R H + P+ G +V N+ + V
Sbjct: 1282 PQPKLTWFKDGRPLARGDAHHISPD-----GVLLQVLQANLSSAGHYSCIAANAVG---- 1332
Query: 1164 GITYEPPNYKALDFSEAPSFTQPLVNRS-----VIAGYTAMLCCAVRGSPKPKISWFKNG 1218
E + L AP+ + + V L C P P I+W K+G
Sbjct: 1333 ----EKTKHFQLSVLLAPTILGGAEDSADEEVTVTVNNPISLICEALAFPSPNITWMKDG 1388
Query: 1219 LDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVRVP 1273
++ G L+I D G Y C TN GEA +EV +P
Sbjct: 1389 APFEASRNIQLLP--GTHGLQILNAQKEDAGQYTCVVTNELGEAVKNYHVEVLIP 1441
Score = 41.2 bits (95), Expect = 0.006
Identities = 29/80 (36%), Positives = 37/80 (46%), Gaps = 2/80 (2%)
Query: 1191 SVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGI 1250
+ I G L C GSP P I W +NG E A ++ S QG TL I G+
Sbjct: 509 TTIVGQPLELPCQASGSPVPTIQWLQNGRPAEELAGVQVAS-QGT-TLHIDHVELDHSGL 566
Query: 1251 YVCRATNLQGEARCECRLEV 1270
+ C+ATN G A E + V
Sbjct: 567 FACQATNEAGTAGAEVEVSV 586
Score = 40.8 bits (94), Expect = 0.008
Identities = 79/347 (22%), Positives = 125/347 (36%), Gaps = 45/347 (12%)
Query: 941 LFRVRAHNMAGPGAPVTTTE---PVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPF 997
++ +A N G T + P T++ RP + ++ G PV L
Sbjct: 379 VYTCKASNAVGAAEKATRLDVYVPPTIEGAGGRPYV---------VKAVAGRPVALECVA 429
Query: 998 QGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKAT 1057
+G P P ++W EG P+A E R ++L + + SG Y
Sbjct: 430 RGHPSPTLSWHHEGLPVA-ESNESRLETDGSVLRLESPGEASSGLYSCVA----SSPAGE 484
Query: 1058 LVLQVVDKPSPPQDLRVTDAWGLNVALEWKP---PQDVGNTELWGYTVQKADKKTMEWFT 1114
VLQ + P L V + G + +P P + + + + E
Sbjct: 485 AVLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWLQNGRPAEELAG 544
Query: 1115 VLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIP---RPGITYEP-- 1169
V + T + + + + F + N G A + V + PG+ P
Sbjct: 545 VQVASQGTTLHIDHVELDHSGLFACQATNEAG----TAGAEVEVSVHGEWAPGVLEVPIG 600
Query: 1170 -PNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKI--SWFKNGLDLGEDAR 1226
++ S P+ P V+R G+ A PKP + W G GE
Sbjct: 601 QYHWGXEHHSSFPAACDPPVHR----GWGA--------HPKPPLVEGWCSPGSLWGEPTG 648
Query: 1227 FRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVRVP 1273
+ + L+I K D GIY C ATNL GE++ E L+V VP
Sbjct: 649 IPV-AYSLPPPLQIEKVDLRDEGIYTCAATNLAGESKREVALKVLVP 694
Score = 39.7 bits (91), Expect = 0.019
Identities = 79/362 (21%), Positives = 133/362 (36%), Gaps = 60/362 (16%)
Query: 452 PPVLITRPLEDQLVMVGQRVEFECEVSEEGA-QVKWLKDGVELTREETFKYRFKKDGQRH 510
P VL ++ L + G VE +C S QV+W KD + + ++DGQ
Sbjct: 216 PSVLGAGAAQEVLGLAGADVELQCWTSGVPTPQVEWTKDRQPVLPGGPH-LQVQEDGQV- 273
Query: 511 HLIINEAMLEDAGHY---ALCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFK-- 565
L I + + D G Y A +G QA + ++ S V + + +
Sbjct: 274 -LRITGSHVGDEGRYQCVAFSPAGQQARDFQLRVHAPPTIWGSNETGEVAVMEDHLVQLL 332
Query: 566 CEVSDENVRGV-WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACN 624
CE + W K+G L +++ + GR +L + +D Y+ A
Sbjct: 333 CEARGVPTPNITWFKDGALLPTSTKVVYTRGGR--QLQLGRAQSSDAGVYTCKASN-AVG 389
Query: 625 LSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQ 684
+ K ++V + PP I + G P + VAG + L+ G P+PT+ W
Sbjct: 390 AAEKATRLDVYV-------PPTI--EGAGGRPYVVKAVAGRPVALECVARGHPSPTLSWH 440
Query: 685 KAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKE 744
P ++ E R+ET D S+ +E +
Sbjct: 441 H--------EGLPVAESNES---------------------RLET--DGSVLRLESPGEA 469
Query: 745 DEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEP---PAYDGGQ 801
G+Y+ +P GE + +V+V P A + V T+ +P P G
Sbjct: 470 SSGLYSCVASSPAGEAVLQYSVEVQVPPQLLVAEGLGQV----TTIVGQPLELPCQASGS 525
Query: 802 PI 803
P+
Sbjct: 526 PV 527
Score = 39.7 bits (91), Expect = 0.019
Identities = 33/97 (34%), Positives = 38/97 (39%), Gaps = 3/97 (3%)
Query: 1175 LDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQG 1234
L AP F + +V +G L C G P P I W + G L R R G
Sbjct: 3112 LVLQSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTL-PDG 3170
Query: 1235 VLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVR 1271
L LE + D G Y C A NL G A L VR
Sbjct: 3171 SLWLENVE--TGDAGTYDCVAHNLLGSATARAFLVVR 3205
Score = 39.3 bits (90), Expect = 0.024
Identities = 39/146 (26%), Positives = 60/146 (41%), Gaps = 9/146 (6%)
Query: 956 VTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLA 1015
V T+ V+ + + P LQ + + VG + L +G P P + W K+G PL
Sbjct: 3012 VGRTQAVSFVHVKEAPVLQ--GEAFSYLVEPVGGSIQLDCVVRGDPVPDIHWIKDGLPLR 3069
Query: 1016 GEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKP---SPPQDL 1072
G +R+ + L I R +G YQ E K ++L + P PQD+
Sbjct: 3070 GSH--LRHQLQNGSLTIHRTERDDAGRYQCLAENEMGVAKKVVILVLQSAPVFQVEPQDM 3127
Query: 1073 RVTDAWGLNVALEWKPPQDVGNTELW 1098
V G +VAL + + T W
Sbjct: 3128 TVRS--GDDVALRCQATGEPTPTIEW 3151
Score = 38.9 bits (89), Expect = 0.032
Identities = 24/77 (31%), Positives = 34/77 (44%), Gaps = 11/77 (14%)
Query: 1202 CAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLE-----IRKPCPFDGGIYVCRAT 1256
C G+PKP+++W K + + + GV LE + P D G Y C+AT
Sbjct: 24 CGTHGTPKPQVTWRKG------PSSEPLHGQPGVAVLEEGSLFLASVSPADSGDYECQAT 77
Query: 1257 NLQGEARCECRLEVRVP 1273
N G +L V VP
Sbjct: 78 NEVGSTSRRAKLVVYVP 94
Score = 35.8 bits (81), Expect = 0.27
Identities = 64/306 (20%), Positives = 112/306 (36%), Gaps = 36/306 (11%)
Query: 391 DAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCV----VGGEKCSTE 446
+ + W K+GQ + + K+ + G L + D Y C VG +
Sbjct: 2875 EPNITWDKDGQPVSGAEGKFTIQPSGE---LLVKNLEGQDAGTYTCTAENAVGRARRRVH 2931
Query: 447 LFVKEPPVLITRPLEDQLVMVGQRVEFECEV-SEEGAQVKWLKDGVELTREETFKYRFKK 505
L + PV T P D+ + +G R+ C ++ W + +T + ++
Sbjct: 2932 LTILVLPVFTTLP-GDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEGVS-----EQ 2985
Query: 506 DGQRHHLIINEAMLEDAGHYALCTSG--GQALAELIVQEKKLEVYQ--SIADLMVGAKDQ 561
DG L ED+G Y G+ A V K+ V Q + + L+
Sbjct: 2986 DGGST-LQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVKEAPVLQGEAFSYLVEPVGGS 3044
Query: 562 AVFKCEVSDENVRGV-WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEG 620
C V + V + W+K+G +P + H + LTI D Y + E
Sbjct: 3045 IQLDCVVRGDPVPDIHWIKDG---LPLRGSHLRHQLQNGSLTIHRTERDDAGRYQCLAEN 3101
Query: 621 FACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPT 680
+ K+ + Q P ++ P + V +G+ + L +G+P PT
Sbjct: 3102 EMG--------VAKKVVILVLQSAPVFQVE-----PQDMTVRSGDDVALRCQATGEPTPT 3148
Query: 681 VIWQKA 686
+ W +A
Sbjct: 3149 IEWLQA 3154
Score = 32.7 bits (73), Expect = 2.3
Identities = 28/87 (32%), Positives = 43/87 (49%), Gaps = 10/87 (11%)
Query: 999 GKPRPQVTWTK--EGQPLAGEE-VSIRNSPTDTILFIRAARRVHSGTY--QVTVRIENME 1053
G P+PQVTW K +PL G+ V++ + LF+ + SG Y Q T + +
Sbjct: 28 GTPKPQVTWRKGPSSEPLHGQPGVAVLEEGS---LFLASVSPADSGDYECQATNEVGSTS 84
Query: 1054 DKATLVLQVVDKPSPPQDLRVTDAWGL 1080
+A LV+ V PS +D R + G+
Sbjct: 85 RRAKLVVYV--PPSIREDGRKANVSGM 109
Score = 30.8 bits (68), Expect = 8.6
Identities = 19/63 (30%), Positives = 29/63 (46%), Gaps = 2/63 (3%)
Query: 981 QTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHS 1040
Q + + G+ V L G+P P + W + GQPL +R P D L++ +
Sbjct: 3125 QDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASR-RLRTLP-DGSLWLENVETGDA 3182
Query: 1041 GTY 1043
GTY
Sbjct: 3183 GTY 3185
>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 5065
Score = 108 bits (269), Expect = 4e-23
Identities = 213/921 (23%), Positives = 333/921 (36%), Gaps = 172/921 (18%)
Query: 394 VKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCSTE----LFV 449
+ WL+NG S + E + L +S +AD A+Y CV + S E L V
Sbjct: 2877 ISWLQNGLPFSPSPRLQVLED---GQVLQVSTAEVADAASYMCVAENQAGSAEKLFTLRV 2933
Query: 450 KEPPVLITRPLEDQLVMVGQRVEFECEV-SEEGAQVKWLKDGVELTREETFKYRFKKDGQ 508
+ PP + LE ++ V C+V + +V W KD L+ E F G
Sbjct: 2934 QVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEV---FLLPGT 2990
Query: 509 RHHLIINEAMLEDAGHY---ALCTSG-GQALAEL--IVQEKKLEVYQSIAD-LMVGAKDQ 561
H L + A L D+G Y AL +G Q L +L +V + + D ++V D+
Sbjct: 2991 -HTLQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRVGDK 3049
Query: 562 AVFKCEVSDENVRGV-WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEG 620
AV CE V W K+G+ LV R + G+ +L I + +D+ YS
Sbjct: 3050 AVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQ--RLEIQEAQVSDKGLYSCKVSN 3107
Query: 621 FACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPT 680
A + + + P E PK +T+ VAG+ L L +SG PAPT
Sbjct: 3108 VA---GEAVRTFTLTVQVPPTFENPKT---------ETVSQVAGSPLVLTCDVSGVPAPT 3155
Query: 681 VIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEG 740
V W K R+ VE++ + + G
Sbjct: 3156 VTWLK-------------------------------------DRMPVESSAVHGVVSRGG 3178
Query: 741 ------AEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEP 794
+ G YT +N E + + V V+ AP+I + G V E
Sbjct: 3179 RLQLSRLQPAQAGTYTCVAENTQAEARKDFVVAVL------VAPRIRSSG-----VAREH 3227
Query: 795 PAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEG---VVYEMRVYAVNA 851
+G + L + + W++ L Q++ R ++G V+ +R A
Sbjct: 3228 HVLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGA 3287
Query: 852 IGMSRPSPASQP--FMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYC 909
+PA + + PT D S T VS RP E V C
Sbjct: 3288 YTCVAHNPAGEDARLHTVNVLVPPTIKQGADGSGTLVS---RPGELV---------TMVC 3335
Query: 910 PEGCSEWVAALQGLTEHTSILVKDLPT---------GARLLFRVRAHNMAGPGA-PVTTT 959
P S + H S L LP G+ R+ +A G
Sbjct: 3336 PVRGSPPI--------HVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAA 3387
Query: 960 EPVTVQE-----ILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPL 1014
P V + +Q P + P + + G V L +G P P V+W K+G+PL
Sbjct: 3388 SPAGVADRNFTLQVQVPPVLEPVEFQNDVVVVRGSLVELPCEARGVPLPLVSWMKDGEPL 3447
Query: 1015 AGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKP-----SPP 1069
+ S+ P+ L + A SGTY E E + L V++ P P
Sbjct: 3448 LSQ--SLEQGPS---LQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEPPHIEDSGQP 3502
Query: 1070 QDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPEL 1129
+L +T + + + + T W K + T LE+ R V L
Sbjct: 3503 TELSLTPGAPMELLCDAQGTPQPNIT--W--------HKDGQALTRLENNSRATRV---L 3549
Query: 1130 IIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVN 1189
+ + + +++ G +++ + PPN P F L
Sbjct: 3550 RVRDAGLYTCLAESPAGAIEKSFRVR----------VQAPPNIVG---PRGPRFVVGLAP 3596
Query: 1190 RSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGG 1249
++ L C+V P PKI+W ++G+ L EDA F ++G L+++ D G
Sbjct: 3597 GQLV------LECSVEAEPAPKITWHRDGIVLQEDAH-TQFPERGRF-LQLQALSTADSG 3648
Query: 1250 IYVCRATNLQGEARCECRLEV 1270
Y C A N G R+E+
Sbjct: 3649 DYSCTARNAAGSTSVAFRVEI 3669
Score = 89.0 bits (219), Expect = 3e-17
Identities = 211/925 (22%), Positives = 323/925 (34%), Gaps = 163/925 (17%)
Query: 388 ADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQC----VVGGEKC 443
A + EV W K+ Q + + ++ + TL + + L+D Y C G ++
Sbjct: 2963 AHPNPEVTWYKDSQALSLGEEVFL---LPGTHTLQLGRARLSDSGMYTCEALNAAGRDQK 3019
Query: 444 STELFVKEPPVLITRPLEDQ---LVMVGQRVEFECEVSE-EGAQVKWLKDGVELTREETF 499
+L V PP P Q LV VG + CE V W KDG L +
Sbjct: 3020 LVQLSVLVPPAFRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQ-- 3077
Query: 500 KYRFKKDGQRHHLIINEAMLEDAGHYALCTSG--GQALAELIVQEKKLEVYQSIADLMVG 557
+ + + GQR L I EA + D G Y+ S G+A+ + + +++ V
Sbjct: 3078 RTQALRGGQR--LEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKTETVS 3135
Query: 558 --AKDQAVFKCEVSDENVRGV-WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADY 614
A V C+VS V WLK+ + +S + R +L + + PA Y
Sbjct: 3136 QVAGSPLVLTCDVSGVPAPTVTWLKD--RMPVESSAVHGVVSRGGRLQLSRLQPAQAGTY 3193
Query: 615 SFVPEGFACNLSAKLHFMEVKIDFVPRQ-EPPKIHLDCPGRIPDTIVVVAGNKLRLDVPI 673
+ V E N A E + DFV P+I R V+ G ++RLD
Sbjct: 3194 TCVAE----NTQA-----EARKDFVVAVLVAPRIRSSGVAREHH---VLEGQEVRLDCEA 3241
Query: 674 SGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDR 733
G P P V W K +D G + D L
Sbjct: 3242 DGQPPPDVAWLK-----------DGSPLGQDMGPHLRFYLDGGSL--------------- 3275
Query: 734 SIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAP-----AAPKISNVGE--- 785
++G D G YT NP GED TV V+ P + +S GE
Sbjct: 3276 ---VLKGLRASDAGAYTCVAHNPAGEDARLHTVNVLVPPTIKQGADGSGTLVSRPGELVT 3332
Query: 786 DSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMR 845
C V+ PP + W++ L LS R ++ G + +R
Sbjct: 3333 MVCPVRGSPPIH------------------VSWLKDGLPL--PLSQ--RTLLHGSGHTLR 3370
Query: 846 VYAV--------NAIGMSRPSPASQPF---MPIGPPSEPTHLAVEDVSDTTVSLKWRPPE 894
+ V + S A + F + + P EP DV SL P E
Sbjct: 3371 ISKVQLADAGIFTCVAASPAGVADRNFTLQVQVPPVLEPVEFQ-NDVVVVRGSLVELPCE 3429
Query: 895 RVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGA 954
A G+ V + +G Q L + S+ ++ + G + A + AG
Sbjct: 3430 ---ARGVPLPLVSWMKDG---EPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEAR 3483
Query: 955 ---PVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEG 1011
+T EP +++ Q L L G P+ LL QG P+P +TW K+G
Sbjct: 3484 RHFQLTVMEPPHIEDSGQPTELSL----------TPGAPMELLCDAQGTPQPNITWHKDG 3533
Query: 1012 QPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQD 1071
Q L E NS +L +R A G Y + + ++V +PP
Sbjct: 3534 QALTRLE---NNSRATRVLRVRDA-----GLYTCLAESPAGAIEKSFRVRV---QAPP-- 3580
Query: 1072 LRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWF---TVLEHYRRTHCVVPE 1128
+ G + P Q V +V+ + W VL+ H PE
Sbjct: 3581 -NIVGPRGPRFVVGLAPGQLVLEC-----SVEAEPAPKITWHRDGIVLQ--EDAHTQFPE 3632
Query: 1129 LIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLV 1188
G + ++ + + D + T + + + + P V
Sbjct: 3633 ----RGRFLQLQALSTADSGDYSCTARNAA--GSTSVAFRVEIHTVPTIRSGPPAVNVSV 3686
Query: 1189 NRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDG 1248
N++ + L C G P P +SW K+ + L D R F +L I+ D
Sbjct: 3687 NQTAL------LPCQADGVPAPLVSWRKDRVPL--DPRSPRFEILPEGSLRIQPVLAQDA 3738
Query: 1249 GIYVCRATNLQGEARCECRLEVRVP 1273
G Y+C A+N G R L V P
Sbjct: 3739 GHYLCLASNSAGSDRQGRDLRVLEP 3763
Score = 72.0 bits (175), Expect = 3e-12
Identities = 306/1379 (22%), Positives = 459/1379 (33%), Gaps = 311/1379 (22%)
Query: 11 AFSKKPR----SVEVAAGSPAVFEAETERAGVK-VRWQRGGSDISASNKYGLATEGTRHT 65
AF + PR +V V G AV ET+ V W + G + + + G R
Sbjct: 3030 AFRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQR-- 3087
Query: 66 LTVREVGPADQGSYAV----IAGSSKVKFDLKV-----IEAEKAEPMLAPAPAPAEATGA 116
L ++E +D+G Y+ +AG + F L V E K E + A +P T
Sbjct: 3088 LEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCD 3147
Query: 117 PGEAPAPAA------------------------ELGESAPSPKGSSSAALNGPTPGAPDD 152
PAP +L P+ G+ + A D
Sbjct: 3148 VSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAENTQAEARKD 3207
Query: 153 PIGLFVMRPQ--------DGEVTVGGSITFSARVAGASLLKPPVVKWFKGKWVDLSSKVG 204
+ ++ P+ + V G + G PP V W K L +G
Sbjct: 3208 FVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQP---PPDVAWLKDG-SPLGQDMG 3263
Query: 205 QHLQLHDSYDRASKVYLFELHITDAQPAFTGSYRCEVSTKDKFDCSNFNLTV-------H 257
HL+ Y + L L +DA G+Y C D + V
Sbjct: 3264 PHLRF---YLDGGSLVLKGLRASDA-----GAYTCVAHNPAGEDARLHTVNVLVPPTIKQ 3315
Query: 258 EAMGTGDLDLLSAFRRTSLAG--GGRRISDSHEDTGI-LDFSSLLKKRDSFRTPRDSKLE 314
A G+G L T + G I S G+ L S S T R SK++
Sbjct: 3316 GADGSGTLVSRPGELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQ 3375
Query: 315 APAEEDVWEILRQAP--------------PSEYERIAFQYGVTDLRGMLKRLKGMRRDEK 360
A+ ++ + +P P E + FQ V +RG L L R
Sbjct: 3376 L-ADAGIFTCVAASPAGVADRNFTLQVQVPPVLEPVEFQNDVVVVRGSLVELPCEAR--- 3431
Query: 361 KSTAFQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRT 420
G + L V W+K+G+ + + +S+ +
Sbjct: 3432 -----------------GVPLPL----------VSWMKDGEPL-------LSQSLEQGPS 3457
Query: 421 LTISQCSLADDAAYQCVV----GGEKCSTELFVKEPPVLITRPLEDQLVMV-GQRVEFEC 475
L + D Y CV G + +L V EPP + +L + G +E C
Sbjct: 3458 LQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEPPHIEDSGQPTELSLTPGAPMELLC 3517
Query: 476 EVS-EEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQA 534
+ + W KDG LTR E + R ++ + DAG Y C + A
Sbjct: 3518 DAQGTPQPNITWHKDGQALTRLE--------NNSRATRVLR---VRDAGLYT-CLAESPA 3565
Query: 535 LAELIVQEKKLEVYQSIADLMVG----------AKDQAVFKCEVSDENVRGV-WLKNGKE 583
A EK V +VG A Q V +C V E + W ++G
Sbjct: 3566 GAI----EKSFRVRVQAPPNIVGPRGPRFVVGLAPGQLVLECSVEAEPAPKITWHRDGIV 3621
Query: 584 LVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVP--R 641
L D+ + GR L + ++ AD DYS A + S V+I VP R
Sbjct: 3622 LQEDAHTQFPERGRF--LQLQALSTADSGDYSCTARNAAGSTSVAFR---VEIHTVPTIR 3676
Query: 642 QEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDA 701
PP ++ V L G PAP V W+K ++ P P
Sbjct: 3677 SGPPAVN------------VSVNQTALLPCQADGVPAPLVSWRK-----DRVPLDPRSPR 3719
Query: 702 PEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQ 761
E EG +R++ +D G Y N G D+
Sbjct: 3720 FEIL---------------PEGSLRIQPVL-----------AQDAGHYLCLASNSAGSDR 3753
Query: 762 VNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGG-QPIL-----GYILE-RKKKK 814
++V++ P AP SN+ + T P G +P++ G L+ R ++
Sbjct: 3754 QGRDLRVLEPP--AIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQG 3811
Query: 815 SYRWMRLNFDLIQELSHEARRMIEGVV----------YEMRVYAVNAIGMSRPSPASQPF 864
+YR + N L+ + E VV Y++ V+ I +
Sbjct: 3812 AYRLLPSNALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVHVPPTIADDQTDFTVTMM 3871
Query: 865 MPIGPPSEPTHLAVEDVSDTTVSLKW-RPPERVGAGGLDGYSVEYCPEGCSEWVAALQGL 923
P+ T + VS W + ++GA G GY V P G E
Sbjct: 3872 APVVLTCHSTGIPAPTVS-------WSKAGAQLGARG-SGYRVS--PSGALE-------- 3913
Query: 924 TEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTI 983
+ + LP A + A N AG +TVQ + + L +
Sbjct: 3914 ------IGQALPIHAGR-YTCSARNSAGVAHKHVF---LTVQAS------PVVKPLPSVV 3957
Query: 984 QKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTY 1043
+ E V L G PRP +TW KEG +A VS + P + A+ +G Y
Sbjct: 3958 RAVAEEEVLLPCEASGIPRPTITWQKEGLNVA-TGVSTQVLPGGQLRIAHASPE-DAGNY 4015
Query: 1044 QVTVRIE--NMEDKATLVLQV---VDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELW 1098
+ + K LV+QV ++ P DL T+ G + L K W
Sbjct: 4016 LCIAKNSAGSAMGKTRLVVQVPPVIENGLP--DLSTTE--GSHAFLPCKARGSPEPNITW 4071
Query: 1099 ---GYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTK 1155
G V A+ K FT+ +V L + + ++N VG + R
Sbjct: 4072 DKDGQPVSGAEGK----FTIQPS---GELLVKNLEGQDAGTYTCTAENAVGRARRRVHLT 4124
Query: 1156 E---PVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKI 1212
PVF PG +RS+ G L CA RGSP P+I
Sbjct: 4125 ILVLPVFTTLPG------------------------DRSLRLGDRLWLRCAARGSPTPRI 4160
Query: 1213 SWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVR 1271
W N + E + + G TL+ D G YVC A N G + + V+
Sbjct: 4161 GWTVNDRPVTEG----VSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVK 4215
Score = 67.8 bits (164), Expect = 6e-11
Identities = 194/963 (20%), Positives = 324/963 (33%), Gaps = 175/963 (18%)
Query: 375 VSKGHKIRLTVE-LADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAA 433
V+ + I L E LA + W+K+G + S + + + L I D
Sbjct: 2553 VTVNNPISLICEALAFPSPNITWMKDGAPFEASRN---IQLLPGTHGLQILNAQKEDAGQ 2609
Query: 434 YQCVVGGE------KCSTELFVKEPPVLITRPL-----EDQLVMVGQRVEFECEV-SEEG 481
Y CVV E E+ + P + PL ++ V + ECE +
Sbjct: 2610 YTCVVTNELGEAVKNYHVEVLIP-PSISKDDPLGEVGVKEVKTKVNSTLTLECESWAVPP 2668
Query: 482 AQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTS---GGQALAEL 538
++W KDG +T R + G+ L I + D+G Y LC + G+ +
Sbjct: 2669 PTIRWYKDGQPVTPSS----RLQVLGEGRLLQIQPTQVSDSGRY-LCVATNVAGEDDQDF 2723
Query: 539 IVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDENVRG----------------------- 575
V + ++Q + D A F+ +E RG
Sbjct: 2724 NVLIQVPPMFQKVGDF------SAAFEILSREEEARGGVTEYREIVENNPAYLYCDTNAI 2777
Query: 576 -----VWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLH 630
W + + L + V GRV L I V + YS C S ++
Sbjct: 2778 PPPDLTWYREDQPLSAGDEVSVLQGGRV--LQIPLVRAENAGRYS-------CKASNEVG 2828
Query: 631 FMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQG 690
E + + P + L + + + V A + + L P G+P PT+ W +
Sbjct: 2829 --EDWLHYELLVLTPPVILGDTEELVEEVTVNASSTVSLQCPALGNPVPTISWLQ----- 2881
Query: 691 NKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYT 750
N P P+P R++ +D + V AE D Y
Sbjct: 2882 NGLPFSPSP--------------------------RLQVLEDGQVLQVSTAEVADAASYM 2915
Query: 751 VTVKNPVGEDQVNLTVKVIDVPDAPAA---PKISNVGEDSCTVQWEPPAYDGGQPILGYI 807
+N G + T++V VP A +++ + S ++ + A+ + + Y
Sbjct: 2916 CVAENQAGSAEKLFTLRV-QVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPE-VTWY- 2972
Query: 808 LERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPI 867
K + + L ++ ++ + + +Y A+ + +
Sbjct: 2973 ------KDSQALSLGEEVFLLPGTHTLQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVL 3026
Query: 868 GPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEW---------VA 918
PP+ A D + RVG + + PE W
Sbjct: 3027 VPPA--FRQAPRGPQDAVL-------VRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQ 3077
Query: 919 ALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRH 978
Q L + +++ + L+ + N+AG A T T V V + P+
Sbjct: 3078 RTQALRGGQRLEIQEAQVSDKGLYSCKVSNVAGE-AVRTFTLTVQVPPTFENPK------ 3130
Query: 979 LRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRV 1038
+T+ + G P+ L G P P VTW K+ P+ V S + R +
Sbjct: 3131 -TETVSQVAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSR-LQPA 3188
Query: 1039 HSGTYQVTVRIENMEDKATLVLQVVDKP-----SPPQDLRVTDAW--GLNVALEWKPPQD 1091
+GTY E + V+ V+ P ++ V + L+ + +PP D
Sbjct: 3189 QAGTYTCVAENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPPD 3248
Query: 1092 VGNTELWGYTVQKADKKTMEWFTVLEHY-RRTHCVVPELIIGNGYYFRVFSQNMVGFSDR 1150
V W ++ + L Y V+ L + + + N G R
Sbjct: 3249 VA----W---LKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAGEDAR 3301
Query: 1151 AATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKP 1210
T V PP K + + LV+R G + C VRGSP
Sbjct: 3302 LHTVNVLV----------PPTIK-----QGADGSGTLVSR---PGELVTMVCPVRGSPPI 3343
Query: 1211 KISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
+SW K+GL L R + TL I K D GI+ C A + G A L+V
Sbjct: 3344 HVSWLKDGLPLPLSQRTLLHGSGH--TLRISKVQLADAGIFTCVAASPAGVADRNFTLQV 3401
Query: 1271 RVP 1273
+VP
Sbjct: 3402 QVP 3404
Score = 67.4 bits (163), Expect = 8e-11
Identities = 199/929 (21%), Positives = 320/929 (34%), Gaps = 136/929 (14%)
Query: 370 EPAYQVSKGHKIRLTVEL-ADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSL 428
+ A V G K L+ E A + V W K+GQ + ++ +++ + L I + +
Sbjct: 3039 QDAVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQRT---QALRGGQRLEIQEAQV 3095
Query: 429 ADDAAYQCVVG---GEKCST-ELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQ- 483
+D Y C V GE T L V+ PP E + G + C+VS A
Sbjct: 3096 SDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCDVSGVPAPT 3155
Query: 484 VKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAE-----L 538
V WLKD + + E + + G R L ++ AG Y QA A
Sbjct: 3156 VTWLKDRMPV--ESSAVHGVVSRGGR--LQLSRLQPAQAGTYTCVAENTQAEARKDFVVA 3211
Query: 539 IVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDENVRGV-WLKNGKELVPDSRIKVSHIGR 597
++ ++ + V + CE + V WLK+G L D +
Sbjct: 3212 VLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLD 3271
Query: 598 VHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPD 657
L + + +D Y+ V A A+LH + V + PP I G
Sbjct: 3272 GGSLVLKGLRASDAGAYTCVAHNPAGE-DARLHTVNVLV-------PPTIKQGADGS--G 3321
Query: 658 TIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKL 717
T+V G + + P+ G P V W K P P ++
Sbjct: 3322 TLVSRPGELVTMVCPVRGSPPIHVSWLK--------DGLPLP-------------LSQRT 3360
Query: 718 LCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAA 777
L G + + D G++T +P G N T++V VP
Sbjct: 3361 LLHGSGHT----------LRISKVQLADAGIFTCVAASPAGVADRNFTLQV-QVPPVLEP 3409
Query: 778 PKISNVGEDSCTVQW---EPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEAR 834
+ N D V+ E P G P+ WM+ L+ + +
Sbjct: 3410 VEFQN---DVVVVRGSLVELPCEARGVPL----------PLVSWMKDGEPLLSQSLEQGP 3456
Query: 835 RMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPE 894
+ V + + +S A + F EP H+ + T +SL P
Sbjct: 3457 SLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLT--VMEPPHIE-DSGQPTELSLTPGAPM 3513
Query: 895 RVGAGGLDGYSVEYCPEGCSEWVAALQGLT--EHTSILVKDLPTGARLLFRVRAHNMAGP 952
+ + P+ W Q LT E+ S + L L+ A + AG
Sbjct: 3514 ELLC------DAQGTPQPNITWHKDGQALTRLENNSRATRVLRVRDAGLYTCLAESPAGA 3567
Query: 953 GAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQ 1012
+ + V VQ P + PR R + G+ V L + +P P++TW ++G
Sbjct: 3568 ---IEKSFRVRVQA---PPNIVGPRGPRFVVGLAPGQLV-LECSVEAEPAPKITWHRDGI 3620
Query: 1013 PLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPS----- 1067
L E+ + L ++A SG Y T R +++ P+
Sbjct: 3621 VLQ-EDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGSTSVAFRVEIHTVPTIRSGP 3679
Query: 1068 PPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVP 1127
P ++ V L + P V W D ++ + + E R + P
Sbjct: 3680 PAVNVSVNQTALLPCQADGVPAPLVS----WRKDRVPLDPRSPRFEILPEGSLR---IQP 3732
Query: 1128 ELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPL 1187
L G+Y + S N G SDR + L E P+
Sbjct: 3733 VLAQDAGHYLCLAS-NSAG-SDRQG--------------------RDLRVLEPPAIAPSP 3770
Query: 1188 VNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLG---EDARFRMFSKQGVLTLEIRKPC 1244
N ++ A A+L C GSPKP + W+K+G L + +R+ +L + P
Sbjct: 3771 SNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNALL---LTAPG 3827
Query: 1245 PFDGGIYVCRATNLQGEARCECRLEVRVP 1273
P D + C +N GEA ++ V VP
Sbjct: 3828 PQDSAQFECVVSNEVGEAHRLYQVTVHVP 3856
Score = 65.9 bits (159), Expect = 2e-10
Identities = 208/899 (23%), Positives = 317/899 (35%), Gaps = 156/899 (17%)
Query: 394 VKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVV----GGEKCSTELFV 449
+ W K+GQ + + + A R L + L Y C+ G + S + V
Sbjct: 3527 ITWHKDGQALTR-----LENNSRATRVLRVRDAGL-----YTCLAESPAGAIEKSFRVRV 3576
Query: 450 KEPPVLITRPLEDQLVM---VGQRVEFECEVSEEGA-QVKWLKDGVELTREETFKYRFKK 505
+ PP ++ P + V+ GQ V EC V E A ++ W +DG+ L +E +F +
Sbjct: 3577 QAPPNIVG-PRGPRFVVGLAPGQLV-LECSVEAEPAPKITWHRDGIVL--QEDAHTQFPE 3632
Query: 506 DGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIAD----LMVGAKDQ 561
G+ L + D+G Y+ CT+ A + + ++ +I + V
Sbjct: 3633 RGR--FLQLQALSTADSGDYS-CTARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQT 3689
Query: 562 AVFKCEVSDENVRGV-WLKNGKELVPDS-RIKVSHIGRVHKLTIDDVTPADEADYSFVPE 619
A+ C+ V W K+ L P S R ++ G L I V D Y +
Sbjct: 3690 ALLPCQADGVPAPLVSWRKDRVPLDPRSPRFEILPEG---SLRIQPVLAQDAGHYLCLAS 3746
Query: 620 GFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAP 679
A + ++++ EPP I P + + A L SG P P
Sbjct: 3747 NSA---GSDRQGRDLRV-----LEPPAI-----APSPSNLTLTAHTPALLPCEASGSPKP 3793
Query: 680 TVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIF--T 737
V+W K G K R A +LL + +D + F
Sbjct: 3794 LVVWWK---DGQKLDFRLQQGA-------------YRLLPSNALLLTAPGPQDSAQFECV 3837
Query: 738 VEGAEKEDEGVYTVTVKNP--VGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPP 795
V E +Y VTV P + +DQ + TV ++ AP + G + TV W
Sbjct: 3838 VSNEVGEAHRLYQVTVHVPPTIADDQTDFTVTMM----APVVLTCHSTGIPAPTVSWSKA 3893
Query: 796 AYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMI------EGVVYEMRVYAV 849
G GY + ++ Q L A R GV ++ V
Sbjct: 3894 GAQLGARGSGYRVSPSGA---------LEIGQALPIHAGRYTCSARNSAGVAHKHVFLTV 3944
Query: 850 NAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYC 909
A + +P P+ + E L E ++ W ++ G G S +
Sbjct: 3945 QASPVVKPLPS----VVRAVAEEEVLLPCEASGIPRPTITW---QKEGLNVATGVSTQVL 3997
Query: 910 PEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQ 969
P G Q H S P A + A N AG A T V V +++
Sbjct: 3998 PGG--------QLRIAHAS------PEDAGNYLCI-AKNSAG-SAMGKTRLVVQVPPVIE 4041
Query: 970 RPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTI 1029
LP + G L +G P P +TW K+GQP++G E P+ +
Sbjct: 4042 NG---LP-----DLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGEL 4093
Query: 1030 LFIRAARRVHSGTYQVTV-----RIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVAL 1084
L ++ +GTY T R LVL V + LR+ D L A
Sbjct: 4094 L-VKNLEGQDAGTYTCTAENAVGRARRRVHLTILVLPVFTTLPGDRSLRLGDRLWLRCAA 4152
Query: 1085 EWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNM 1144
P T G+TV D+ E V E + + + + +++N
Sbjct: 4153 RGSP------TPRIGWTVN--DRPVTE--GVSEQDGGSTLQRAAVSREDSGTYVCWAENR 4202
Query: 1145 VGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAV 1204
VG T+ F+ E P + FS +P+ G + L C V
Sbjct: 4203 VG------RTQAVSFVH----VKEAPVLQGEAFS---YLVEPV-------GGSIQLDCVV 4242
Query: 1205 RGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEAR 1263
RG P P I W K+GL L + R + G LT I + D G Y C A N G A+
Sbjct: 4243 RGDPVPDIHWIKDGLPL-RGSHLRHQLQNGSLT--IHRTERDDAGRYQCLAENEMGVAK 4298
Score = 65.5 bits (158), Expect = 3e-10
Identities = 92/348 (26%), Positives = 135/348 (38%), Gaps = 62/348 (17%)
Query: 942 FRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKP 1001
+R A N+AG +TE + PR+ LP L + V PV L G P
Sbjct: 1954 YRCVASNVAG------STELRYGLRVNVPPRITLPPSLPGPVL--VNTPVRLTCNATGAP 2005
Query: 1002 RPQVTWTKEGQPLAGEEV-SIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVL 1060
P + W K+G P++ ++ P +L + +AR SG Y ED+ +VL
Sbjct: 2006 SPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVL 2065
Query: 1061 QVVDKPSP-PQDLRVTDAWGLNVALEWK-----PP-----QDVGNTELWGYTVQKADKKT 1109
QV PS ++L V+ +VALE + PP +D E ADK
Sbjct: 2066 QVHMPPSILGEELNVSVVANESVALECQSHAMPPPVLSWWKDGRPLEPRPGVHLSADKAL 2125
Query: 1110 MEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTK---EPVFIPRPGIT 1166
++ V + + ++ + N G S++ PVF R T
Sbjct: 2126 LQ--------------VDRADVWDAGHYTCEALNQAGHSEKHYNLNVWVAPVFPLRESHT 2171
Query: 1167 YEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDL-GEDA 1225
+V G+ L C RG P PKISW K+G L GE A
Sbjct: 2172 L-----------------------TVREGHPTSLSCECRGVPFPKISWRKDGQPLPGEGA 2208
Query: 1226 RFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVRVP 1273
+ S G L L + + G Y C +N+ G + + +LEV VP
Sbjct: 2209 GLQHVSAVGRL-LYLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVP 2255
Score = 65.1 bits (157), Expect = 4e-10
Identities = 80/318 (25%), Positives = 121/318 (38%), Gaps = 59/318 (18%)
Query: 976 PRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRN-SPTDTILFIRA 1034
P T+ + G P +L +G P P+++W K+GQPL GE +++ S +L++
Sbjct: 2165 PLRESHTLTVREGHPTSLSCECRGVPFPKISWRKDGQPLPGEGAGLQHVSAVGRLLYLGQ 2224
Query: 1035 ARRVHSGTYQ------VTVRIENMEDKATLVLQVVDKPSPPQDLRVTD--AWGLNVALEW 1086
A+ GTY V ++++ + + Q+ PP + V L
Sbjct: 2225 AQLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQIAGPREPPTQVSVVQDGVATLECNATG 2284
Query: 1087 KPP---------QDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYF 1137
KPP Q VG EL G +Q + H R CV
Sbjct: 2285 KPPPTVTWERDGQPVG-AEL-GLQLQNQGQSLHVERAQAAHTGRYSCV------------ 2330
Query: 1138 RVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYT 1197
++N+ G ++R V +P P LD PL N +
Sbjct: 2331 ---AENLAGRAERKFELS--VLVP-------PELIGDLD---------PLTNITAALHSP 2369
Query: 1198 AMLCCAVRGSPKPKISWFK--NGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRA 1255
L C G P P I WF+ + GED + G L++ + D G+Y C A
Sbjct: 2370 LTLLCEAMGIPPPAIRWFRGEEPVSPGEDT----YLLAGGWMLKMTQTQEQDSGLYSCLA 2425
Query: 1256 TNLQGEARCECRLEVRVP 1273
+N GEAR +EV VP
Sbjct: 2426 SNEAGEARRNFSVEVLVP 2443
Score = 58.5 bits (140), Expect = 4e-08
Identities = 87/361 (24%), Positives = 127/361 (35%), Gaps = 48/361 (13%)
Query: 923 LTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQT 982
L E S+ + G L+ RA N AG T ++ P L Q
Sbjct: 1365 LDEGQSLHFPRIQEGDSGLYSCRAENQAG-------TAQRDFHLLVLTPPSVLGAGAAQE 1417
Query: 983 IQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGT 1042
+ G V L G P PQV WTK+ QP+ ++ +L I + G
Sbjct: 1418 VLGLAGADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHVGDEGR 1477
Query: 1043 YQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTV 1102
YQ + L+V P+ WG N E +D L
Sbjct: 1478 YQCVAFSPAGQQARDFQLRVHAPPT---------IWGSNETGEVAVMEDHLVQLLC--EA 1526
Query: 1103 QKADKKTMEWFTVLEHYRRTHCVV-----PELIIGNGY-----YFRVFSQNMVGFSDRAA 1152
+ + WF + VV +L +G + + N VG +++A
Sbjct: 1527 RGVPTPNITWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGAAEKAT 1586
Query: 1153 TTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKI 1212
Y PP + +P V ++V AG L C RG P P +
Sbjct: 1587 RLD----------VYVPPTIEGAG-------GRPYVVKAV-AGRPVALECVARGHPSPTL 1628
Query: 1213 SWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVRV 1272
SW GL + E R+ + VL LE P G+Y C A++ GEA + +EV+V
Sbjct: 1629 SWHHEGLPVAESNESRLETDGSVLRLE--SPGEASSGLYSCVASSPAGEAVLQYSVEVQV 1686
Query: 1273 P 1273
P
Sbjct: 1687 P 1687
Score = 56.6 bits (135), Expect = 1e-07
Identities = 146/685 (21%), Positives = 241/685 (35%), Gaps = 120/685 (17%)
Query: 393 EVKWLKNGQEIQMSGSKYIFESIGAK-RTLTISQCSLADDAAYQCVVGGEKCSTE----L 447
+V W K Q + S ++ ++ R L I Q L+D +Y+CV STE L
Sbjct: 1916 DVSWFKGHQPV----SSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASNVAGSTELRYGL 1971
Query: 448 FVKEPPVLITRPLEDQLVMVGQRVEFECEVS-EEGAQVKWLKDGVELTREETFKYRFKKD 506
V PP + P V+V V C + + WLKDG ++ T +
Sbjct: 1972 RVNVPPRITLPPSLPGPVLVNTPVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPG 2031
Query: 507 GQRHHLIINEAMLEDAGHYA--LCTSGGQALAELIVQ-EKKLEVYQSIADLMVGAKDQAV 563
G+ L + A D+G Y+ ++ G+ ++++Q + ++ V A +
Sbjct: 2032 GR--VLTLASARASDSGRYSCVAVSAVGEDRQDVVLQVHMPPSILGEELNVSVVANESVA 2089
Query: 564 FKCEVSDENVRGV--WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGF 621
+C+ S V W K+G+ L P + +S + L +D D Y+
Sbjct: 2090 LECQ-SHAMPPPVLSWWKDGRPLEPRPGVHLSADKAL--LQVDRADVWDAGHYTCEALNQ 2146
Query: 622 ACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTV 681
A + S K + + V + V P R T+ V G+ L G P P +
Sbjct: 2147 AGH-SEKHYNLNVWVAPV-----------FPLRESHTLTVREGHPTSLSCECRGVPFPKI 2194
Query: 682 IWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGA 741
W+K +P P EG + + + A
Sbjct: 2195 SWRK--------DGQPLPG---------------------EGAGLQHVSAVGRLLYLGQA 2225
Query: 742 EKEDEGVYTVTVKNPVGEDQVNLTVKVIDVP----------------DAPAAPKISNVGE 785
+ EG YT N VG +L ++V P D A + + G+
Sbjct: 2226 QLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQIAGPREPPTQVSVVQDGVATLECNATGK 2285
Query: 786 DSCTVQWEPPAYDGGQPI---LGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVY 842
TV WE GQP+ LG L+ + + L+ + Q +H R
Sbjct: 2286 PPPTVTWE----RDGQPVGAELGLQLQNQGQS------LHVERAQ-AAHTGRYSCVAENL 2334
Query: 843 EMRVYAVNAIGMSRPSPASQPFMPI----GPPSEPTHLAVEDVSDTTVSLKWRPPERVGA 898
R + + P P+ P L E + +++W E +
Sbjct: 2335 AGRAERKFELSVLVPPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWFRGEEPVS 2394
Query: 899 GGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTT 958
G D Y + W+ + E S L L A N AG +
Sbjct: 2395 PGEDTYLL------AGGWMLKMTQTQEQDSGLYSCL-----------ASNEAGEARRNFS 2437
Query: 959 TEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEE 1018
E+L P ++ L + I+ G+ +L+ G P+P++TW K+G+PLA +
Sbjct: 2438 V------EVLVPPSIE-NEDLEEVIKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGD 2490
Query: 1019 VSIRNSPTDTILFIRAARRVHSGTY 1043
SP +L + A +G Y
Sbjct: 2491 AH-HISPDGVLLQVLQANLSSAGHY 2514
Score = 48.9 bits (115), Expect = 3e-05
Identities = 91/436 (20%), Positives = 151/436 (34%), Gaps = 76/436 (17%)
Query: 369 LEPAYQVSKGHKIRLTVELADH-DAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCS 427
LE +V G L + H ++ W K+G+ + + +I L + Q +
Sbjct: 2451 LEEVIKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHHISPD---GVLLQVLQAN 2507
Query: 428 LADDAAYQCVVG---GEKCST-ELFVKEPPVLI----TRPLEDQLVMVGQRVEFECE-VS 478
L+ Y C+ GEK +L V P ++ E+ V V + CE ++
Sbjct: 2508 LSSAGHYSCIAANAVGEKTKHFQLSVLLAPTILGGAEDSADEEVTVTVNNPISLICEALA 2567
Query: 479 EEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSG--GQALA 536
+ W+KDG + H L I A EDAG Y + G+A+
Sbjct: 2568 FPSPNITWMKDGAPFEASRNIQLL----PGTHGLQILNAQKEDAGQYTCVVTNELGEAVK 2623
Query: 537 ELIVQ----------EKKLEVYQSIADLMVGAKDQAVFKCE---VSDENVRGVWLKNGKE 583
V+ + EV + ++ +CE V +R W K+G+
Sbjct: 2624 NYHVEVLIPPSISKDDPLGEV--GVKEVKTKVNSTLTLECESWAVPPPTIR--WYKDGQP 2679
Query: 584 LVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFA------CNLSAKLHFMEVKI- 636
+ P SR++V GR+ L I +D Y V A N+ ++ M K+
Sbjct: 2680 VTPSSRLQVLGEGRL--LQIQPTQVSDSGRYLCVATNVAGEDDQDFNVLIQVPPMFQKVG 2737
Query: 637 DFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPAR 696
DF E + G + + +V N L + P P + W +
Sbjct: 2738 DFSAAFEILSREEEARGGVTEYREIVENNPAYLYCDTNAIPPPDLTWYR----------- 2786
Query: 697 PAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNP 756
D P GD V + + + E+ G Y+ N
Sbjct: 2787 --EDQPLSAGD------------------EVSVLQGGRVLQIPLVRAENAGRYSCKASNE 2826
Query: 757 VGEDQVNLTVKVIDVP 772
VGED ++ + V+ P
Sbjct: 2827 VGEDWLHYELLVLTPP 2842
Score = 48.1 bits (113), Expect = 5e-05
Identities = 29/98 (29%), Positives = 48/98 (48%), Gaps = 9/98 (9%)
Query: 1175 LDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQG 1234
L +++ PS + V G A+L C G P P++ W++ GL++ + + +G
Sbjct: 692 LYYTDPPSVSAVNAVVLVAVGEEAVLVCEASGVPPPRVIWYRGGLEM-------ILAPEG 744
Query: 1235 VLTLEIRKPC--PFDGGIYVCRATNLQGEARCECRLEV 1270
+ ++R P D G Y CRA N G+A E +L V
Sbjct: 745 SSSGKLRIPAAQERDAGTYTCRAVNELGDASAEIQLAV 782
Score = 48.1 bits (113), Expect = 5e-05
Identities = 34/90 (37%), Positives = 40/90 (44%), Gaps = 6/90 (6%)
Query: 1181 PSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEI 1240
P+ T + N G A L C G P P I+W K L SK+G TL I
Sbjct: 980 PTATHHITNE----GVPASLPCVASGVPAPTITWTKETNALTSRGPHYNVSKEG--TLLI 1033
Query: 1241 RKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
+P D G YVC ATN G + E RL V
Sbjct: 1034 AQPSAQDAGAYVCTATNTVGFSSQEMRLSV 1063
Score = 48.1 bits (113), Expect = 5e-05
Identities = 71/290 (24%), Positives = 106/290 (36%), Gaps = 34/290 (11%)
Query: 408 SKYIFESIGA--KRTLTISQCSLADDAAYQCVVGGEKCSTE----LFVKEPPVLITRPLE 461
SKY++E G +L ++Q + D Y+C S L V+ PP + P
Sbjct: 1069 SKYVWEEYGLLPSGSLRLAQVQVGDSGHYECTASNPAGSASHRYVLGVQVPPQVQPGPRV 1128
Query: 462 DQLVMVGQRVEFECEVS-EEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLE 520
+ V+VG+ ++ C Q+ W KDGV L G H I +
Sbjct: 1129 LK-VLVGEALDLNCVAEGNPEPQLSWSKDGVVLQGRGP-------QGSVHFAAIRTS--- 1177
Query: 521 DAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVG-----AKDQAVFKCEVSDENVRG 575
DAG Y S + V+ + LE AD G A + A C
Sbjct: 1178 DAGRYRCEASNSAGVDAWEVELRVLEPPHWGADETSGLLERVAGENASLPCPARGTPKPQ 1237
Query: 576 VWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVK 635
V + G P + L + V+PAD DY C + ++ +
Sbjct: 1238 VTWRKGPSSEPLHGQPGVAVLEEGSLFLASVSPADSGDYE-------CQATNEVGSTSRR 1290
Query: 636 IDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQK 685
V PP I D GR + + +AG L L+ +G P P ++W K
Sbjct: 1291 AKLVV-YVPPSIRED--GRKAN-VSGMAGQSLTLECDANGFPVPEIVWLK 1336
Score = 47.8 bits (112), Expect = 7e-05
Identities = 36/111 (32%), Positives = 51/111 (45%), Gaps = 20/111 (18%)
Query: 1168 EPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARF 1227
EPP++ A + T L+ R +AG A L C RG+PKP+++W K +
Sbjct: 1203 EPPHWGADE-------TSGLLER--VAGENASLPCPARGTPKPQVTWRKG------PSSE 1247
Query: 1228 RMFSKQGVLTLE-----IRKPCPFDGGIYVCRATNLQGEARCECRLEVRVP 1273
+ + GV LE + P D G Y C+ATN G +L V VP
Sbjct: 1248 PLHGQPGVAVLEEGSLFLASVSPADSGDYECQATNEVGSTSRRAKLVVYVP 1298
Score = 47.4 bits (111), Expect = 9e-05
Identities = 88/381 (23%), Positives = 138/381 (36%), Gaps = 57/381 (14%)
Query: 322 WEILRQAPPSEYERIAFQYGVTDLRGMLKRLKGMRRDEKKSTAFQKKLEPA--YQVSKGH 379
WEILR + E G + + + G + + T +L PA VS G
Sbjct: 481 WEILRASKAEE--------GTYECTAVSRAGTGRAKAQIVVTDPPPQLVPAPNVTVSPGE 532
Query: 380 KIRLTVE-LADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVV 438
L+ L + + W+++ + + S + + A +L IS D YQCV
Sbjct: 533 TAVLSCRVLGEAPYNLTWVRDWRVLPASTGRV---AQLADLSLEISGIIPTDGGRYQCVA 589
Query: 439 ----GGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGA-QVKWLKDGVEL 493
G + S L V+E P ++ Q G V+ C S + W ++ L
Sbjct: 590 SNANGVTRASVWLLVREAPQ-VSIHTSSQHFSQGVEVKVSCSASGYPTPHISWSRESQAL 648
Query: 494 TREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSI-- 551
+ R D Q LII EDAG+Y+ QA E+ ++ + +Y +
Sbjct: 649 QEDS----RIHVDAQGT-LIIQGVAPEDAGNYSC-----QATNEVGTDQETVTLYYTDPP 698
Query: 552 ------ADLMVGAKDQAVFKCEVSD-ENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTID 604
A ++V ++AV CE S R +W + G E++ S KL I
Sbjct: 699 SVSAVNAVVLVAVGEEAVLVCEASGVPPPRVIWYRGGLEMILAPEGSSSG-----KLRIP 753
Query: 605 DVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAG 664
D Y+ C +L +I P L P + V G
Sbjct: 754 AAQERDAGTYT-------CRAVNELGDASAEIQLAVGHAPQLTEL------PRDVTVELG 800
Query: 665 NKLRLDVPISGDPAPTVIWQK 685
L +G P PTV W++
Sbjct: 801 RSALLACRATGRPPPTVTWRR 821
Score = 46.6 bits (109), Expect = 2e-04
Identities = 32/80 (40%), Positives = 41/80 (51%), Gaps = 4/80 (5%)
Query: 1192 VIAGYTAMLCCAVRGSPKPKISWFKNGLDLGE-DARFRMFSKQGVLTLEIRKPCPFDGGI 1250
V+ G TA L C V G P+PK++WFK+G L DA S GVL L++ + G
Sbjct: 2457 VLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHH--ISPDGVL-LQVLQANLSSAGH 2513
Query: 1251 YVCRATNLQGEARCECRLEV 1270
Y C A N GE +L V
Sbjct: 2514 YSCIAANAVGEKTKHFQLSV 2533
Score = 45.8 bits (107), Expect = 3e-04
Identities = 30/93 (32%), Positives = 41/93 (44%), Gaps = 4/93 (4%)
Query: 1181 PSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDL-GEDARFRMFSKQGVLTLE 1239
P L + S G A L C RGSP+P I+W K+G + G + +F + +L
Sbjct: 4038 PVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKN 4097
Query: 1240 IRKPCPFDGGIYVCRATNLQGEARCECRLEVRV 1272
+ D G Y C A N G AR L + V
Sbjct: 4098 LEGQ---DAGTYTCTAENAVGRARRRVHLTILV 4127
Score = 45.1 bits (105), Expect = 4e-04
Identities = 31/88 (35%), Positives = 42/88 (47%), Gaps = 4/88 (4%)
Query: 1186 PLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCP 1245
P V R+V A +L C G P+P I+W K GL++ ++ L I P
Sbjct: 3954 PSVVRAV-AEEEVLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPGG---QLRIAHASP 4009
Query: 1246 FDGGIYVCRATNLQGEARCECRLEVRVP 1273
D G Y+C A N G A + RL V+VP
Sbjct: 4010 EDAGNYLCIAKNSAGSAMGKTRLVVQVP 4037
Score = 44.7 bits (104), Expect = 6e-04
Identities = 29/82 (35%), Positives = 39/82 (47%), Gaps = 3/82 (3%)
Query: 1179 EAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTL 1238
EAP + ++ G + C+ G P P ISW + L ED+R + QG TL
Sbjct: 606 EAPQVSIHTSSQHFSQGVEVKVSCSASGYPTPHISWSRESQALQEDSRIHV-DAQG--TL 662
Query: 1239 EIRKPCPFDGGIYVCRATNLQG 1260
I+ P D G Y C+ATN G
Sbjct: 663 IIQGVAPEDAGNYSCQATNEVG 684
Score = 44.3 bits (103), Expect = 8e-04
Identities = 36/104 (34%), Positives = 48/104 (46%), Gaps = 12/104 (11%)
Query: 1175 LDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKN-----GLDLGEDARFRM 1229
L AP T+ + +V G +A+L C G P P ++W + GL LG R
Sbjct: 780 LAVGHAPQLTELPRDVTVELGRSALLACRATGRPPPTVTWRRGDGQPLGLRLGAGRGSR- 838
Query: 1230 FSKQ---GVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
S+Q GVL E P D YVC A N+ G+ + E RL V
Sbjct: 839 -SRQPDSGVLFFE--SVAPEDQAPYVCEARNVFGKVQAEARLIV 879
Score = 43.5 bits (101), Expect = 0.001
Identities = 95/442 (21%), Positives = 159/442 (35%), Gaps = 85/442 (19%)
Query: 393 EVKWLKNGQEI----------------QMSGSKYIFESIGAKRTLTISQCSLADDAAYQC 436
E+ WLK+ Q + Q+ G + + E ++L + D Y C
Sbjct: 1331 EIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEG----QSLHFPRIQEGDSGLYSC 1386
Query: 437 ----VVGGEKCSTELFVKEPP-VLITRPLEDQLVMVGQRVEFECEVSEEGA-QVKWLKDG 490
G + L V PP VL ++ L + G VE +C S QV+W KD
Sbjct: 1387 RAENQAGTAQRDFHLLVLTPPSVLGAGAAQEVLGLAGADVELQCWTSGVPTPQVEWTKDR 1446
Query: 491 VELTREETFKYRFKKDGQRHHLIINEAMLEDAGHY---ALCTSGGQALAELIVQEKKLEV 547
+ + ++DGQ L I + + D G Y A +G QA + +
Sbjct: 1447 QPVLPGGPH-LQVQEDGQV--LRITGSHVGDEGRYQCVAFSPAGQQARDFQLRVHAPPTI 1503
Query: 548 YQSIADLMVGAKDQAVFK--CEVSDENVRGV-WLKNGKELVPDSRIKVSHIGRVHKLTID 604
+ S V + + + CE + W K+G L +++ + GR +L +
Sbjct: 1504 WGSNETGEVAVMEDHLVQLLCEARGVPTPNITWFKDGALLPTSTKVVYTRGGR--QLQLG 1561
Query: 605 DVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAG 664
+D Y+ A + K ++V + PP I + G P + VAG
Sbjct: 1562 RAQSSDAGVYTCKASN-AVGAAEKATRLDVYV-------PPTI--EGAGGRPYVVKAVAG 1611
Query: 665 NKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGR 724
+ L+ G P+PT+ W P ++ E
Sbjct: 1612 RPVALECVARGHPSPTLSWHH--------EGLPVAESNES-------------------- 1643
Query: 725 VRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPKISNVG 784
R+ET D S+ +E + G+Y+ +P GE + +V+V P A + V
Sbjct: 1644 -RLET--DGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSVEVQVPPQLLVAEGLGQV- 1699
Query: 785 EDSCTVQWEP---PAYDGGQPI 803
T+ +P P G P+
Sbjct: 1700 ---TTIVGQPLELPCQASGSPV 1718
Score = 43.1 bits (100), Expect = 0.002
Identities = 85/378 (22%), Positives = 134/378 (35%), Gaps = 58/378 (15%)
Query: 914 SEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRL 973
S++V GL S+ + + G + A N AG + ++ PR+
Sbjct: 1069 SKYVWEEYGLLPSGSLRLAQVQVGDSGHYECTASNPAGSASHRYVLGVQVPPQVQPGPRV 1128
Query: 974 QLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIR 1033
++ VGE ++L +G P PQ++W+K+G L G P ++ F
Sbjct: 1129 ---------LKVLVGEALDLNCVAEGNPEPQLSWSKDGVVLQG------RGPQGSVHF-A 1172
Query: 1034 AARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLR---VTDAWGLNVALEWKPPQ 1090
A R +G Y+ D + L+V++ P D + G N +L
Sbjct: 1173 AIRTSDAGRYRCEASNSAGVDAWEVELRVLEPPHWGADETSGLLERVAGENASLPCPARG 1232
Query: 1091 DVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDR 1150
W VLE V G+ + + N VG + R
Sbjct: 1233 TPKPQVTWRKGPSSEPLHGQPGVAVLEEGSLFLASVSPADSGD---YECQATNEVGSTSR 1289
Query: 1151 AATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKP 1210
A + Y PP+ + D +A N S +AG + L C G P P
Sbjct: 1290 RAKL----------VVYVPPSIRE-DGRKA--------NVSGMAGQSLTLECDANGFPVP 1330
Query: 1211 KISWFKN-------------GLDL--GEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRA 1255
+I W K+ G DL G+ R+ + +L + D G+Y CRA
Sbjct: 1331 EIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEG--QSLHFPRIQEGDSGLYSCRA 1388
Query: 1256 TNLQGEARCECRLEVRVP 1273
N G A+ + L V P
Sbjct: 1389 ENQAGTAQRDFHLLVLTP 1406
Score = 42.7 bits (99), Expect = 0.002
Identities = 31/94 (32%), Positives = 43/94 (45%), Gaps = 2/94 (2%)
Query: 1178 SEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLT 1237
++ P P N +V G TA+L C V G ++W ++ L A ++ L+
Sbjct: 514 TDPPPQLVPAPNVTVSPGETAVLSCRVLGEAPYNLTWVRDWRVL--PASTGRVAQLADLS 571
Query: 1238 LEIRKPCPFDGGIYVCRATNLQGEARCECRLEVR 1271
LEI P DGG Y C A+N G R L VR
Sbjct: 572 LEISGIIPTDGGRYQCVASNANGVTRASVWLLVR 605
Score = 42.0 bits (97), Expect = 0.004
Identities = 184/895 (20%), Positives = 291/895 (32%), Gaps = 154/895 (17%)
Query: 421 LTISQCSLADDAAYQC----VVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECE 476
L I + L D+ Y C + G K L V PP + P+ ++ V+ V EC
Sbjct: 1850 LQIEKVDLRDEGIYTCAATNLAGESKREVALKVLVPPNIEPGPV-NKAVLENASVTLECL 1908
Query: 477 VSE-EGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQAL 535
S V W K ++ DG+ L I +A L DAG Y S
Sbjct: 1909 ASGVPPPDVSWFKGHQPVS--SWMGVTVSVDGRV--LRIEQAQLSDAGSYRCVASNVAGS 1964
Query: 536 AEL-----IVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSR- 589
EL + ++ + S+ ++ + + +WLK+G + P
Sbjct: 1965 TELRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTCNATGAPSPTLMWLKDGNPVSPAGTP 2024
Query: 590 -IKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIH 648
++V GRV LT+ +D YS V A E + D V + P
Sbjct: 2025 GLQVFPGGRV--LTLASARASDSGRYSCV---------AVSAVGEDRQDVVLQVHMP--- 2070
Query: 649 LDCPGRIPD--TIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTG 706
P + + + VVA + L+ P P + W K + P P P
Sbjct: 2071 ---PSILGEELNVSVVANESVALECQSHAMPPPVLSWWK-----DGRPLEPRPG------ 2116
Query: 707 DSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTV 766
V + D+++ V+ A+ D G YT N G + + +
Sbjct: 2117 --------------------VHLSADKALLQVDRADVWDAGHYTCEALNQAGHSEKHYNL 2156
Query: 767 KVIDVPDAPAAPKISNVGED------SCTVQWEP-PAYD---GGQPILGYILERKKKKSY 816
V P P + + SC + P P GQP+ G + +
Sbjct: 2157 NVWVAPVFPLRESHTLTVREGHPTSLSCECRGVPFPKISWRKDGQPLPGEGAGLQHVSAV 2216
Query: 817 RWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMP---IGPPSEP 873
RL + +L+ E E N +G S + +P GP P
Sbjct: 2217 G--RLLYLGQAQLAQEGTYTCE---------CSNVVGNSSQDLQLEVHVPPQIAGPREPP 2265
Query: 874 THLAV--EDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILV 931
T ++V + V+ + +PP V DG P G LQ + S+ V
Sbjct: 2266 TQVSVVQDGVATLECNATGKPPPTV-TWERDGQ-----PVGAE---LGLQLQNQGQSLHV 2316
Query: 932 KDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPV 991
+ + A N+AG E +L P L I + P+
Sbjct: 2317 ERAQAAHTGRYSCVAENLAG------RAERKFELSVLVPPELIGDLDPLTNITAALHSPL 2370
Query: 992 NLLIPFQGKPRPQVTWTKEGQPLA-GEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIE 1050
LL G P P + W + +P++ GE+ + +L + + SG Y E
Sbjct: 2371 TLLCEAMGIPPPAIRWFRGEEPVSPGEDTYLLAG--GWMLKMTQTQEQDSGLYSCLASNE 2428
Query: 1051 NMEDKATLVLQVVDKPSPPQD-----LRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKA 1105
E + ++V+ PS + ++V D G T V
Sbjct: 2429 AGEARRNFSVEVLVPPSIENEDLEEVIKVLD----------------GQTAHLMCNVTGH 2472
Query: 1106 DKKTMEWFTVLEHYRR--THCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRP 1163
+ + WF R H + P+ G +V N+ + V
Sbjct: 2473 PQPKLTWFKDGRPLARGDAHHISPD-----GVLLQVLQANLSSAGHYSCIAANAVG---- 2523
Query: 1164 GITYEPPNYKALDFSEAPSFTQPLVNRS-----VIAGYTAMLCCAVRGSPKPKISWFKNG 1218
E + L AP+ + + V L C P P I+W K+G
Sbjct: 2524 ----EKTKHFQLSVLLAPTILGGAEDSADEEVTVTVNNPISLICEALAFPSPNITWMKDG 2579
Query: 1219 LDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVRVP 1273
++ G L+I D G Y C TN GEA +EV +P
Sbjct: 2580 APFEASRNIQLLP--GTHGLQILNAQKEDAGQYTCVVTNELGEAVKNYHVEVLIP 2632
Score = 41.2 bits (95), Expect = 0.006
Identities = 29/80 (36%), Positives = 37/80 (46%), Gaps = 2/80 (2%)
Query: 1191 SVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGI 1250
+ I G L C GSP P I W +NG E A ++ S QG TL I G+
Sbjct: 1700 TTIVGQPLELPCQASGSPVPTIQWLQNGRPAEELAGVQVAS-QGT-TLHIDHVELDHSGL 1757
Query: 1251 YVCRATNLQGEARCECRLEV 1270
+ C+ATN G A E + V
Sbjct: 1758 FACQATNEAGTAGAEVEVSV 1777
Score = 40.8 bits (94), Expect = 0.008
Identities = 79/347 (22%), Positives = 125/347 (36%), Gaps = 45/347 (12%)
Query: 941 LFRVRAHNMAGPGAPVTTTE---PVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPF 997
++ +A N G T + P T++ RP + ++ G PV L
Sbjct: 1570 VYTCKASNAVGAAEKATRLDVYVPPTIEGAGGRPYV---------VKAVAGRPVALECVA 1620
Query: 998 QGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKAT 1057
+G P P ++W EG P+A E R ++L + + SG Y
Sbjct: 1621 RGHPSPTLSWHHEGLPVA-ESNESRLETDGSVLRLESPGEASSGLYSCVA----SSPAGE 1675
Query: 1058 LVLQVVDKPSPPQDLRVTDAWGLNVALEWKP---PQDVGNTELWGYTVQKADKKTMEWFT 1114
VLQ + P L V + G + +P P + + + + E
Sbjct: 1676 AVLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWLQNGRPAEELAG 1735
Query: 1115 VLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIP---RPGITYEP-- 1169
V + T + + + + F + N G A + V + PG+ P
Sbjct: 1736 VQVASQGTTLHIDHVELDHSGLFACQATNEAG----TAGAEVEVSVHGEWAPGVLEVPIG 1791
Query: 1170 -PNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKI--SWFKNGLDLGEDAR 1226
++ S P+ P V+R G+ A PKP + W G GE
Sbjct: 1792 QYHWGXEHHSSFPAACDPPVHR----GWGA--------HPKPPLVEGWCSPGSLWGEPTG 1839
Query: 1227 FRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVRVP 1273
+ + L+I K D GIY C ATNL GE++ E L+V VP
Sbjct: 1840 IPV-AYSLPPPLQIEKVDLRDEGIYTCAATNLAGESKREVALKVLVP 1885
Score = 39.7 bits (91), Expect = 0.019
Identities = 33/110 (30%), Positives = 46/110 (41%), Gaps = 18/110 (16%)
Query: 577 WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLH-FMEVK 635
WLK+G+ L P SR + G +H +D YS V A N + H +E+
Sbjct: 919 WLKDGRPLPPGSRHSIRADGSLH---LDRALQEHAGRYSCV----ATNTAGSQHRDVELV 971
Query: 636 IDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQK 685
+ PR P H +P ++ VA SG PAPT+ W K
Sbjct: 972 VQVPPRIHPTATHHITNEGVPASLPCVA----------SGVPAPTITWTK 1011
Score = 39.7 bits (91), Expect = 0.019
Identities = 33/97 (34%), Positives = 38/97 (39%), Gaps = 3/97 (3%)
Query: 1175 LDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQG 1234
L AP F + +V +G L C G P P I W + G L R R G
Sbjct: 4303 LVLQSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTL-PDG 4361
Query: 1235 VLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVR 1271
L LE + D G Y C A NL G A L VR
Sbjct: 4362 SLWLENVE--TGDAGTYDCVAHNLLGSATARAFLVVR 4396
Score = 39.3 bits (90), Expect = 0.024
Identities = 39/146 (26%), Positives = 60/146 (41%), Gaps = 9/146 (6%)
Query: 956 VTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLA 1015
V T+ V+ + + P LQ + + VG + L +G P P + W K+G PL
Sbjct: 4203 VGRTQAVSFVHVKEAPVLQ--GEAFSYLVEPVGGSIQLDCVVRGDPVPDIHWIKDGLPLR 4260
Query: 1016 GEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKP---SPPQDL 1072
G +R+ + L I R +G YQ E K ++L + P PQD+
Sbjct: 4261 GSH--LRHQLQNGSLTIHRTERDDAGRYQCLAENEMGVAKKVVILVLQSAPVFQVEPQDM 4318
Query: 1073 RVTDAWGLNVALEWKPPQDVGNTELW 1098
V G +VAL + + T W
Sbjct: 4319 TVRS--GDDVALRCQATGEPTPTIEW 4342
Score = 38.1 bits (87), Expect = 0.054
Identities = 61/311 (19%), Positives = 115/311 (36%), Gaps = 61/311 (19%)
Query: 503 FKKDGQRHHLIINEAMLEDAGHYALCTSG---GQALAELIVQEKKLEVYQSIADLMVGAK 559
F++ G I+ + E+ + S G+A A+++V + ++ + ++ V
Sbjct: 473 FQESGNSSWEILRASKAEEGTYECTAVSRAGTGRAKAQIVVTDPPPQLVPA-PNVTVSPG 531
Query: 560 DQAVFKCEVSDENVRGV-WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVP 618
+ AV C V E + W+++ + L P S +V+ + + L I + P D Y V
Sbjct: 532 ETAVLSCRVLGEAPYNLTWVRDWRVL-PASTGRVAQLADL-SLEISGIIPTDGGRYQCVA 589
Query: 619 EGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPA 678
A + + +E P++ + + G ++++ SG P
Sbjct: 590 SNANGVTRASVWLLV--------REAPQVSIHTSSQH-----FSQGVEVKVSCSASGYPT 636
Query: 679 PTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTV 738
P + W + + + + R+ V+ + +
Sbjct: 637 PHISWSR-----------------------------ESQALQEDSRIHVDA---QGTLII 664
Query: 739 EGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPA--APKISNVGEDS---CTVQWE 793
+G ED G Y+ N VG DQ +T+ D P A A + VGE++ C
Sbjct: 665 QGVAPEDAGNYSCQATNEVGTDQETVTLYYTDPPSVSAVNAVVLVAVGEEAVLVCEASGV 724
Query: 794 PPA----YDGG 800
PP Y GG
Sbjct: 725 PPPRVIWYRGG 735
Score = 38.1 bits (87), Expect = 0.054
Identities = 31/99 (31%), Positives = 47/99 (47%), Gaps = 7/99 (7%)
Query: 982 TIQKKVGEPVNL-LIPFQGKPRPQVTWTKEGQPL-AGEEVSIRNSPTDTILFIRAARRVH 1039
T++ G+PV+L I G+P P+ W K+G+PL G SIR D L + A + H
Sbjct: 893 TVRVLEGQPVSLPCIVLAGRPLPERHWLKDGRPLPPGSRHSIR---ADGSLHLDRALQEH 949
Query: 1040 SGTYQ--VTVRIENMEDKATLVLQVVDKPSPPQDLRVTD 1076
+G Y T + LV+QV + P +T+
Sbjct: 950 AGRYSCVATNTAGSQHRDVELVVQVPPRIHPTATHHITN 988
Score = 35.8 bits (81), Expect = 0.27
Identities = 64/306 (20%), Positives = 112/306 (36%), Gaps = 36/306 (11%)
Query: 391 DAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCV----VGGEKCSTE 446
+ + W K+GQ + + K+ + G L + D Y C VG +
Sbjct: 4066 EPNITWDKDGQPVSGAEGKFTIQPSGE---LLVKNLEGQDAGTYTCTAENAVGRARRRVH 4122
Query: 447 LFVKEPPVLITRPLEDQLVMVGQRVEFECEV-SEEGAQVKWLKDGVELTREETFKYRFKK 505
L + PV T P D+ + +G R+ C ++ W + +T + ++
Sbjct: 4123 LTILVLPVFTTLP-GDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEGVS-----EQ 4176
Query: 506 DGQRHHLIINEAMLEDAGHYALCTSG--GQALAELIVQEKKLEVYQ--SIADLMVGAKDQ 561
DG L ED+G Y G+ A V K+ V Q + + L+
Sbjct: 4177 DGGST-LQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVKEAPVLQGEAFSYLVEPVGGS 4235
Query: 562 AVFKCEVSDENVRGV-WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEG 620
C V + V + W+K+G +P + H + LTI D Y + E
Sbjct: 4236 IQLDCVVRGDPVPDIHWIKDG---LPLRGSHLRHQLQNGSLTIHRTERDDAGRYQCLAEN 4292
Query: 621 FACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPT 680
+ K+ + Q P ++ P + V +G+ + L +G+P PT
Sbjct: 4293 EMG--------VAKKVVILVLQSAPVFQVE-----PQDMTVRSGDDVALRCQATGEPTPT 4339
Query: 681 VIWQKA 686
+ W +A
Sbjct: 4340 IEWLQA 4345
Score = 34.3 bits (77), Expect = 0.78
Identities = 85/370 (22%), Positives = 128/370 (34%), Gaps = 47/370 (12%)
Query: 916 WVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQL 975
W Q L E + I V T L+ + A AG + T E T QE +
Sbjct: 641 WSRESQALQEDSRIHVDAQGT---LIIQGVAPEDAGNYSCQATNEVGTDQETVTLYYTDP 697
Query: 976 PR--HLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIR 1033
P + + VGE L+ G P P+V W + G E + + L I
Sbjct: 698 PSVSAVNAVVLVAVGEEAVLVCEASGVPPPRVIWYRGGL----EMILAPEGSSSGKLRIP 753
Query: 1034 AARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSP-----PQDLRVTDAWGLNVALEWKP 1088
AA+ +GTY T R N A+ +Q+ +P P+D+ V
Sbjct: 754 AAQERDAGTY--TCRAVNELGDASAEIQLAVGHAPQLTELPRDVTV-------------- 797
Query: 1089 PQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNM-VGF 1147
++G + L T+ W RR L +G G R + V F
Sbjct: 798 --ELGRSALLACRATGRPPPTVTW-------RRGDGQPLGLRLGAGRGSRSRQPDSGVLF 848
Query: 1148 SDRAATTKEPVFIPRPGITYEPPNYKA---LDFSEAPSFTQPLVNRSVIAGYTAMLCCAV 1204
+ A + ++ + +A + P V+ G L C V
Sbjct: 849 FESVAPEDQAPYVCEARNVFGKVQAEARLIVTGHAPPQIASSAPTVRVLEGQPVSLPCIV 908
Query: 1205 -RGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEAR 1263
G P P+ W K+G L +R S + +L + + G Y C ATN G
Sbjct: 909 LAGRPLPERHWLKDGRPLPPGSR---HSIRADGSLHLDRALQEHAGRYSCVATNTAGSQH 965
Query: 1264 CECRLEVRVP 1273
+ L V+VP
Sbjct: 966 RDVELVVQVP 975
Score = 32.7 bits (73), Expect = 2.3
Identities = 22/80 (27%), Positives = 33/80 (41%), Gaps = 2/80 (2%)
Query: 988 GEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTV 1047
G V + G P P ++W++E Q L +E S + L I+ +G Y
Sbjct: 622 GVEVKVSCSASGYPTPHISWSRESQAL--QEDSRIHVDAQGTLIIQGVAPEDAGNYSCQA 679
Query: 1048 RIENMEDKATLVLQVVDKPS 1067
E D+ T+ L D PS
Sbjct: 680 TNEVGTDQETVTLYYTDPPS 699
Score = 30.8 bits (68), Expect = 8.6
Identities = 21/77 (27%), Positives = 32/77 (41%), Gaps = 4/77 (5%)
Query: 973 LQLPRHLRQTIQKKV---GEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTI 1029
+Q+P + T + G P +L G P P +TWTKE L S T+
Sbjct: 972 VQVPPRIHPTATHHITNEGVPASLPCVASGVPAPTITWTKETNALTSRGPHYNVSKEGTL 1031
Query: 1030 LFIRAARRVHSGTYQVT 1046
L + + + +G Y T
Sbjct: 1032 LIAQPSAQ-DAGAYVCT 1047
Score = 30.8 bits (68), Expect = 8.6
Identities = 19/63 (30%), Positives = 29/63 (46%), Gaps = 2/63 (3%)
Query: 981 QTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHS 1040
Q + + G+ V L G+P P + W + GQPL +R P D L++ +
Sbjct: 4316 QDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASR-RLRTLP-DGSLWLENVETGDA 4373
Query: 1041 GTY 1043
GTY
Sbjct: 4374 GTY 4376
>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3783
Score = 108 bits (269), Expect = 4e-23
Identities = 213/921 (23%), Positives = 333/921 (36%), Gaps = 172/921 (18%)
Query: 394 VKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCSTE----LFV 449
+ WL+NG S + E + L +S +AD A+Y CV + S E L V
Sbjct: 1595 ISWLQNGLPFSPSPRLQVLED---GQVLQVSTAEVADAASYMCVAENQAGSAEKLFTLRV 1651
Query: 450 KEPPVLITRPLEDQLVMVGQRVEFECEV-SEEGAQVKWLKDGVELTREETFKYRFKKDGQ 508
+ PP + LE ++ V C+V + +V W KD L+ E F G
Sbjct: 1652 QVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEV---FLLPGT 1708
Query: 509 RHHLIINEAMLEDAGHY---ALCTSG-GQALAEL--IVQEKKLEVYQSIAD-LMVGAKDQ 561
H L + A L D+G Y AL +G Q L +L +V + + D ++V D+
Sbjct: 1709 -HTLQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRVGDK 1767
Query: 562 AVFKCEVSDENVRGV-WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEG 620
AV CE V W K+G+ LV R + G+ +L I + +D+ YS
Sbjct: 1768 AVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQ--RLEIQEAQVSDKGLYSCKVSN 1825
Query: 621 FACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPT 680
A + + + P E PK +T+ VAG+ L L +SG PAPT
Sbjct: 1826 VA---GEAVRTFTLTVQVPPTFENPKT---------ETVSQVAGSPLVLTCDVSGVPAPT 1873
Query: 681 VIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEG 740
V W K R+ VE++ + + G
Sbjct: 1874 VTWLK-------------------------------------DRMPVESSAVHGVVSRGG 1896
Query: 741 ------AEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEP 794
+ G YT +N E + + V V+ AP+I + G V E
Sbjct: 1897 RLQLSRLQPAQAGTYTCVAENTQAEARKDFVVAVL------VAPRIRSSG-----VAREH 1945
Query: 795 PAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEG---VVYEMRVYAVNA 851
+G + L + + W++ L Q++ R ++G V+ +R A
Sbjct: 1946 HVLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGA 2005
Query: 852 IGMSRPSPASQP--FMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYC 909
+PA + + PT D S T VS RP E V C
Sbjct: 2006 YTCVAHNPAGEDARLHTVNVLVPPTIKQGADGSGTLVS---RPGELV---------TMVC 2053
Query: 910 PEGCSEWVAALQGLTEHTSILVKDLPT---------GARLLFRVRAHNMAGPGA-PVTTT 959
P S + H S L LP G+ R+ +A G
Sbjct: 2054 PVRGSPPI--------HVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAA 2105
Query: 960 EPVTVQE-----ILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPL 1014
P V + +Q P + P + + G V L +G P P V+W K+G+PL
Sbjct: 2106 SPAGVADRNFTLQVQVPPVLEPVEFQNDVVVVRGSLVELPCEARGVPLPLVSWMKDGEPL 2165
Query: 1015 AGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKP-----SPP 1069
+ S+ P+ L + A SGTY E E + L V++ P P
Sbjct: 2166 LSQ--SLEQGPS---LQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEPPHIEDSGQP 2220
Query: 1070 QDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPEL 1129
+L +T + + + + T W K + T LE+ R V L
Sbjct: 2221 TELSLTPGAPMELLCDAQGTPQPNIT--W--------HKDGQALTRLENNSRATRV---L 2267
Query: 1130 IIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVN 1189
+ + + +++ G +++ + PPN P F L
Sbjct: 2268 RVRDAGLYTCLAESPAGAIEKSFRVR----------VQAPPNIVG---PRGPRFVVGLAP 2314
Query: 1190 RSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGG 1249
++ L C+V P PKI+W ++G+ L EDA F ++G L+++ D G
Sbjct: 2315 GQLV------LECSVEAEPAPKITWHRDGIVLQEDAH-TQFPERGRF-LQLQALSTADSG 2366
Query: 1250 IYVCRATNLQGEARCECRLEV 1270
Y C A N G R+E+
Sbjct: 2367 DYSCTARNAAGSTSVAFRVEI 2387
Score = 89.0 bits (219), Expect = 3e-17
Identities = 211/925 (22%), Positives = 323/925 (34%), Gaps = 163/925 (17%)
Query: 388 ADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQC----VVGGEKC 443
A + EV W K+ Q + + ++ + TL + + L+D Y C G ++
Sbjct: 1681 AHPNPEVTWYKDSQALSLGEEVFL---LPGTHTLQLGRARLSDSGMYTCEALNAAGRDQK 1737
Query: 444 STELFVKEPPVLITRPLEDQ---LVMVGQRVEFECEVSE-EGAQVKWLKDGVELTREETF 499
+L V PP P Q LV VG + CE V W KDG L +
Sbjct: 1738 LVQLSVLVPPAFRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQ-- 1795
Query: 500 KYRFKKDGQRHHLIINEAMLEDAGHYALCTSG--GQALAELIVQEKKLEVYQSIADLMVG 557
+ + + GQR L I EA + D G Y+ S G+A+ + + +++ V
Sbjct: 1796 RTQALRGGQR--LEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKTETVS 1853
Query: 558 --AKDQAVFKCEVSDENVRGV-WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADY 614
A V C+VS V WLK+ + +S + R +L + + PA Y
Sbjct: 1854 QVAGSPLVLTCDVSGVPAPTVTWLKD--RMPVESSAVHGVVSRGGRLQLSRLQPAQAGTY 1911
Query: 615 SFVPEGFACNLSAKLHFMEVKIDFVPRQ-EPPKIHLDCPGRIPDTIVVVAGNKLRLDVPI 673
+ V E N A E + DFV P+I R V+ G ++RLD
Sbjct: 1912 TCVAE----NTQA-----EARKDFVVAVLVAPRIRSSGVAREHH---VLEGQEVRLDCEA 1959
Query: 674 SGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDR 733
G P P V W K +D G + D L
Sbjct: 1960 DGQPPPDVAWLK-----------DGSPLGQDMGPHLRFYLDGGSL--------------- 1993
Query: 734 SIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAP-----AAPKISNVGE--- 785
++G D G YT NP GED TV V+ P + +S GE
Sbjct: 1994 ---VLKGLRASDAGAYTCVAHNPAGEDARLHTVNVLVPPTIKQGADGSGTLVSRPGELVT 2050
Query: 786 DSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMR 845
C V+ PP + W++ L LS R ++ G + +R
Sbjct: 2051 MVCPVRGSPPIH------------------VSWLKDGLPL--PLSQ--RTLLHGSGHTLR 2088
Query: 846 VYAV--------NAIGMSRPSPASQPF---MPIGPPSEPTHLAVEDVSDTTVSLKWRPPE 894
+ V + S A + F + + P EP DV SL P E
Sbjct: 2089 ISKVQLADAGIFTCVAASPAGVADRNFTLQVQVPPVLEPVEFQ-NDVVVVRGSLVELPCE 2147
Query: 895 RVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGA 954
A G+ V + +G Q L + S+ ++ + G + A + AG
Sbjct: 2148 ---ARGVPLPLVSWMKDG---EPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEAR 2201
Query: 955 ---PVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEG 1011
+T EP +++ Q L L G P+ LL QG P+P +TW K+G
Sbjct: 2202 RHFQLTVMEPPHIEDSGQPTELSL----------TPGAPMELLCDAQGTPQPNITWHKDG 2251
Query: 1012 QPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQD 1071
Q L E NS +L +R A G Y + + ++V +PP
Sbjct: 2252 QALTRLE---NNSRATRVLRVRDA-----GLYTCLAESPAGAIEKSFRVRV---QAPP-- 2298
Query: 1072 LRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWF---TVLEHYRRTHCVVPE 1128
+ G + P Q V +V+ + W VL+ H PE
Sbjct: 2299 -NIVGPRGPRFVVGLAPGQLVLEC-----SVEAEPAPKITWHRDGIVLQ--EDAHTQFPE 2350
Query: 1129 LIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLV 1188
G + ++ + + D + T + + + + P V
Sbjct: 2351 ----RGRFLQLQALSTADSGDYSCTARNAA--GSTSVAFRVEIHTVPTIRSGPPAVNVSV 2404
Query: 1189 NRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDG 1248
N++ + L C G P P +SW K+ + L D R F +L I+ D
Sbjct: 2405 NQTAL------LPCQADGVPAPLVSWRKDRVPL--DPRSPRFEILPEGSLRIQPVLAQDA 2456
Query: 1249 GIYVCRATNLQGEARCECRLEVRVP 1273
G Y+C A+N G R L V P
Sbjct: 2457 GHYLCLASNSAGSDRQGRDLRVLEP 2481
Score = 72.0 bits (175), Expect = 3e-12
Identities = 306/1379 (22%), Positives = 459/1379 (33%), Gaps = 311/1379 (22%)
Query: 11 AFSKKPR----SVEVAAGSPAVFEAETERAGVK-VRWQRGGSDISASNKYGLATEGTRHT 65
AF + PR +V V G AV ET+ V W + G + + + G R
Sbjct: 1748 AFRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQR-- 1805
Query: 66 LTVREVGPADQGSYAV----IAGSSKVKFDLKV-----IEAEKAEPMLAPAPAPAEATGA 116
L ++E +D+G Y+ +AG + F L V E K E + A +P T
Sbjct: 1806 LEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCD 1865
Query: 117 PGEAPAPAA------------------------ELGESAPSPKGSSSAALNGPTPGAPDD 152
PAP +L P+ G+ + A D
Sbjct: 1866 VSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAENTQAEARKD 1925
Query: 153 PIGLFVMRPQ--------DGEVTVGGSITFSARVAGASLLKPPVVKWFKGKWVDLSSKVG 204
+ ++ P+ + V G + G PP V W K L +G
Sbjct: 1926 FVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQP---PPDVAWLKDG-SPLGQDMG 1981
Query: 205 QHLQLHDSYDRASKVYLFELHITDAQPAFTGSYRCEVSTKDKFDCSNFNLTV-------H 257
HL+ Y + L L +DA G+Y C D + V
Sbjct: 1982 PHLRF---YLDGGSLVLKGLRASDA-----GAYTCVAHNPAGEDARLHTVNVLVPPTIKQ 2033
Query: 258 EAMGTGDLDLLSAFRRTSLAG--GGRRISDSHEDTGI-LDFSSLLKKRDSFRTPRDSKLE 314
A G+G L T + G I S G+ L S S T R SK++
Sbjct: 2034 GADGSGTLVSRPGELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQ 2093
Query: 315 APAEEDVWEILRQAP--------------PSEYERIAFQYGVTDLRGMLKRLKGMRRDEK 360
A+ ++ + +P P E + FQ V +RG L L R
Sbjct: 2094 L-ADAGIFTCVAASPAGVADRNFTLQVQVPPVLEPVEFQNDVVVVRGSLVELPCEAR--- 2149
Query: 361 KSTAFQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRT 420
G + L V W+K+G+ + + +S+ +
Sbjct: 2150 -----------------GVPLPL----------VSWMKDGEPL-------LSQSLEQGPS 2175
Query: 421 LTISQCSLADDAAYQCVV----GGEKCSTELFVKEPPVLITRPLEDQLVMV-GQRVEFEC 475
L + D Y CV G + +L V EPP + +L + G +E C
Sbjct: 2176 LQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEPPHIEDSGQPTELSLTPGAPMELLC 2235
Query: 476 EVS-EEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQA 534
+ + W KDG LTR E + R ++ + DAG Y C + A
Sbjct: 2236 DAQGTPQPNITWHKDGQALTRLE--------NNSRATRVLR---VRDAGLYT-CLAESPA 2283
Query: 535 LAELIVQEKKLEVYQSIADLMVG----------AKDQAVFKCEVSDENVRGV-WLKNGKE 583
A EK V +VG A Q V +C V E + W ++G
Sbjct: 2284 GAI----EKSFRVRVQAPPNIVGPRGPRFVVGLAPGQLVLECSVEAEPAPKITWHRDGIV 2339
Query: 584 LVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVP--R 641
L D+ + GR L + ++ AD DYS A + S V+I VP R
Sbjct: 2340 LQEDAHTQFPERGRF--LQLQALSTADSGDYSCTARNAAGSTSVAFR---VEIHTVPTIR 2394
Query: 642 QEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDA 701
PP ++ V L G PAP V W+K ++ P P
Sbjct: 2395 SGPPAVN------------VSVNQTALLPCQADGVPAPLVSWRK-----DRVPLDPRSPR 2437
Query: 702 PEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQ 761
E EG +R++ +D G Y N G D+
Sbjct: 2438 FEIL---------------PEGSLRIQPVL-----------AQDAGHYLCLASNSAGSDR 2471
Query: 762 VNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGG-QPIL-----GYILE-RKKKK 814
++V++ P AP SN+ + T P G +P++ G L+ R ++
Sbjct: 2472 QGRDLRVLEPP--AIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQG 2529
Query: 815 SYRWMRLNFDLIQELSHEARRMIEGVV----------YEMRVYAVNAIGMSRPSPASQPF 864
+YR + N L+ + E VV Y++ V+ I +
Sbjct: 2530 AYRLLPSNALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVHVPPTIADDQTDFTVTMM 2589
Query: 865 MPIGPPSEPTHLAVEDVSDTTVSLKW-RPPERVGAGGLDGYSVEYCPEGCSEWVAALQGL 923
P+ T + VS W + ++GA G GY V P G E
Sbjct: 2590 APVVLTCHSTGIPAPTVS-------WSKAGAQLGARG-SGYRVS--PSGALE-------- 2631
Query: 924 TEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTI 983
+ + LP A + A N AG +TVQ + + L +
Sbjct: 2632 ------IGQALPIHAGR-YTCSARNSAGVAHKHVF---LTVQAS------PVVKPLPSVV 2675
Query: 984 QKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTY 1043
+ E V L G PRP +TW KEG +A VS + P + A+ +G Y
Sbjct: 2676 RAVAEEEVLLPCEASGIPRPTITWQKEGLNVA-TGVSTQVLPGGQLRIAHASPE-DAGNY 2733
Query: 1044 QVTVRIE--NMEDKATLVLQV---VDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELW 1098
+ + K LV+QV ++ P DL T+ G + L K W
Sbjct: 2734 LCIAKNSAGSAMGKTRLVVQVPPVIENGLP--DLSTTE--GSHAFLPCKARGSPEPNITW 2789
Query: 1099 ---GYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTK 1155
G V A+ K FT+ +V L + + ++N VG + R
Sbjct: 2790 DKDGQPVSGAEGK----FTIQPS---GELLVKNLEGQDAGTYTCTAENAVGRARRRVHLT 2842
Query: 1156 E---PVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKI 1212
PVF PG +RS+ G L CA RGSP P+I
Sbjct: 2843 ILVLPVFTTLPG------------------------DRSLRLGDRLWLRCAARGSPTPRI 2878
Query: 1213 SWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVR 1271
W N + E + + G TL+ D G YVC A N G + + V+
Sbjct: 2879 GWTVNDRPVTEG----VSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVK 2933
Score = 68.2 bits (165), Expect = 5e-11
Identities = 197/965 (20%), Positives = 325/965 (33%), Gaps = 179/965 (18%)
Query: 375 VSKGHKIRLTVE-LADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAA 433
V+ + I L E LA + W+K+G + S + + + L I D
Sbjct: 1271 VTVNNPISLICEALAFPSPNITWMKDGAPFEASRN---IQLLPGTHGLQILNAQKEDAGQ 1327
Query: 434 YQCVVGGEKCSTELFVKEPPVLITRP----LEDQLVMVGQR---------VEFECEV-SE 479
Y CVV E VK V + P +D L VG + + ECE +
Sbjct: 1328 YTCVVTNELGEA---VKNYHVEVLIPPSISKDDPLAEVGVKEVKTKVNSTLTLECESWAV 1384
Query: 480 EGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTS---GGQALA 536
++W KDG +T R + G+ L I + D+G Y LC + G+
Sbjct: 1385 PPPTIRWYKDGQPVTPSS----RLQVLGEGRLLQIQPTQVSDSGRY-LCVATNVAGEDDQ 1439
Query: 537 ELIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDENVRG--------------------- 575
+ V + ++Q + D A F+ +E RG
Sbjct: 1440 DFNVLIQVPPMFQKVGDF------SAAFEILSREEEARGGVTEYREIVENNPAYLYCDTN 1493
Query: 576 -------VWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAK 628
W + + L + V GRV L I V + YS C S +
Sbjct: 1494 AIPPPDLTWYREDQPLSAGDEVSVLQGGRV--LQIPLVRAENAGRYS-------CKASNE 1544
Query: 629 LHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAIT 688
+ E + + P + L + + + V A + + L P G+P PT+ W +
Sbjct: 1545 VG--EDWLHYELLVLTPPVILGDTEELVEEVTVNASSTVSLQCPALGNPVPTISWLQ--- 1599
Query: 689 QGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGV 748
N P P+P R++ +D + V AE D
Sbjct: 1600 --NGLPFSPSP--------------------------RLQVLEDGQVLQVSTAEVADAAS 1631
Query: 749 YTVTVKNPVGEDQVNLTVKVIDVPDAPAA---PKISNVGEDSCTVQWEPPAYDGGQPILG 805
Y +N G + T++V VP A +++ + S ++ + A+ + +
Sbjct: 1632 YMCVAENQAGSAEKLFTLRV-QVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPE-VTW 1689
Query: 806 YILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM 865
Y K + + L ++ ++ + + +Y A+ +
Sbjct: 1690 Y-------KDSQALSLGEEVFLLPGTHTLQLGRARLSDSGMYTCEALNAAGRDQKLVQLS 1742
Query: 866 PIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEW--------- 916
+ PP+ A D + RVG + + PE W
Sbjct: 1743 VLVPPA--FRQAPRGPQDAVL-------VRVGDKAVLSCETDALPEPTVTWYKDGQPLVL 1793
Query: 917 VAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLP 976
Q L + +++ + L+ + N+AG A T T V V + P+
Sbjct: 1794 AQRTQALRGGQRLEIQEAQVSDKGLYSCKVSNVAGE-AVRTFTLTVQVPPTFENPK---- 1848
Query: 977 RHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAAR 1036
+T+ + G P+ L G P P VTW K+ P+ V S + R +
Sbjct: 1849 ---TETVSQVAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSR-LQ 1904
Query: 1037 RVHSGTYQVTVRIENMEDKATLVLQVVDKP-----SPPQDLRVTDAW--GLNVALEWKPP 1089
+GTY E + V+ V+ P ++ V + L+ + +PP
Sbjct: 1905 PAQAGTYTCVAENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPP 1964
Query: 1090 QDVGNTELWGYTVQKADKKTMEWFTVLEHY-RRTHCVVPELIIGNGYYFRVFSQNMVGFS 1148
DV W ++ + L Y V+ L + + + N G
Sbjct: 1965 PDVA----W---LKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAGED 2017
Query: 1149 DRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSP 1208
R T V PP K + + LV+R G + C VRGSP
Sbjct: 2018 ARLHTVNVLV----------PPTIK-----QGADGSGTLVSR---PGELVTMVCPVRGSP 2059
Query: 1209 KPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRL 1268
+SW K+GL L R + TL I K D GI+ C A + G A L
Sbjct: 2060 PIHVSWLKDGLPLPLSQRTLLHGSGH--TLRISKVQLADAGIFTCVAASPAGVADRNFTL 2117
Query: 1269 EVRVP 1273
+V+VP
Sbjct: 2118 QVQVP 2122
Score = 67.8 bits (164), Expect = 6e-11
Identities = 209/899 (23%), Positives = 318/899 (35%), Gaps = 156/899 (17%)
Query: 394 VKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVV----GGEKCSTELFV 449
+ W K+GQ + + + A R L + L Y C+ G + S + V
Sbjct: 2245 ITWHKDGQALTR-----LENNSRATRVLRVRDAGL-----YTCLAESPAGAIEKSFRVRV 2294
Query: 450 KEPPVLITRPLEDQLVM---VGQRVEFECEVSEEGA-QVKWLKDGVELTREETFKYRFKK 505
+ PP ++ P + V+ GQ V EC V E A ++ W +DG+ L +E +F +
Sbjct: 2295 QAPPNIVG-PRGPRFVVGLAPGQLV-LECSVEAEPAPKITWHRDGIVL--QEDAHTQFPE 2350
Query: 506 DGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIAD----LMVGAKDQ 561
G+ L + D+G Y+ CT+ A + + ++ +I + V
Sbjct: 2351 RGR--FLQLQALSTADSGDYS-CTARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQT 2407
Query: 562 AVFKCEVSDENVRGV-WLKNGKELVPDS-RIKVSHIGRVHKLTIDDVTPADEADYSFVPE 619
A+ C+ V W K+ L P S R ++ G L I V D Y +
Sbjct: 2408 ALLPCQADGVPAPLVSWRKDRVPLDPRSPRFEILPEG---SLRIQPVLAQDAGHYLCLAS 2464
Query: 620 GFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAP 679
A + ++++ EPP I P + + A L SG P P
Sbjct: 2465 NSA---GSDRQGRDLRV-----LEPPAI-----APSPSNLTLTAHTPALLPCEASGSPKP 2511
Query: 680 TVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIF--T 737
V+W K G K R A +LL + +D + F
Sbjct: 2512 LVVWWK---DGQKLDFRLQQGA-------------YRLLPSNALLLTAPGPQDSAQFECV 2555
Query: 738 VEGAEKEDEGVYTVTVKNP--VGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPP 795
V E +Y VTV P + +DQ + TV ++ AP + G + TV W
Sbjct: 2556 VSNEVGEAHRLYQVTVHVPPTIADDQTDFTVTMM----APVVLTCHSTGIPAPTVSWSKA 2611
Query: 796 AYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMI------EGVVYEMRVYAV 849
G GY + ++ Q L A R GV ++ V
Sbjct: 2612 GAQLGARGSGYRVSPSGA---------LEIGQALPIHAGRYTCSARNSAGVAHKHVFLTV 2662
Query: 850 NAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYC 909
A + +P P+ + E L E ++ W ++ G G S +
Sbjct: 2663 QASPVVKPLPS----VVRAVAEEEVLLPCEASGIPRPTITW---QKEGLNVATGVSTQVL 2715
Query: 910 PEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQ 969
P G Q H S P A + A N AG A T V V +++
Sbjct: 2716 PGG--------QLRIAHAS------PEDAGNYLCI-AKNSAG-SAMGKTRLVVQVPPVIE 2759
Query: 970 RPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTI 1029
LP + G L +G P P +TW K+GQP++G E P+ +
Sbjct: 2760 NG---LP-----DLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGEL 2811
Query: 1030 LFIRAARRVHSGTYQVTV-----RIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVAL 1084
L ++ +GTY T R LVL V + LR+ D L A
Sbjct: 2812 L-VKNLEGQDAGTYTCTAENAVGRARRRVHLTILVLPVFTTLPGDRSLRLGDRLWLRCAA 2870
Query: 1085 EWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNM 1144
P T G+TV D+ E V E + + + + +++N
Sbjct: 2871 RGSP------TPRIGWTVN--DRPVTE--GVSEQDGGSTLQRAAVSREDSGTYVCWAENR 2920
Query: 1145 VGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAV 1204
VG T+ F+ E P + FS +P+ G + L C V
Sbjct: 2921 VG------RTQAVSFVH----VKEAPVLQGEAFS---YLVEPV-------GGSIQLDCVV 2960
Query: 1205 RGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEAR 1263
RG P P I W K+GL L + R + G LT IR+ D G Y C A N G A+
Sbjct: 2961 RGDPVPDIHWIKDGLPL-RGSHLRHQLQNGSLT--IRRTERDDAGRYQCLAENEMGVAK 3016
Score = 67.4 bits (163), Expect = 8e-11
Identities = 199/929 (21%), Positives = 320/929 (34%), Gaps = 136/929 (14%)
Query: 370 EPAYQVSKGHKIRLTVEL-ADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSL 428
+ A V G K L+ E A + V W K+GQ + ++ +++ + L I + +
Sbjct: 1757 QDAVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQRT---QALRGGQRLEIQEAQV 1813
Query: 429 ADDAAYQCVVG---GEKCST-ELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQ- 483
+D Y C V GE T L V+ PP E + G + C+VS A
Sbjct: 1814 SDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCDVSGVPAPT 1873
Query: 484 VKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAE-----L 538
V WLKD + + E + + G R L ++ AG Y QA A
Sbjct: 1874 VTWLKDRMPV--ESSAVHGVVSRGGR--LQLSRLQPAQAGTYTCVAENTQAEARKDFVVA 1929
Query: 539 IVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDENVRGV-WLKNGKELVPDSRIKVSHIGR 597
++ ++ + V + CE + V WLK+G L D +
Sbjct: 1930 VLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLD 1989
Query: 598 VHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPD 657
L + + +D Y+ V A A+LH + V + PP I G
Sbjct: 1990 GGSLVLKGLRASDAGAYTCVAHNPAGE-DARLHTVNVLV-------PPTIKQGADGS--G 2039
Query: 658 TIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKL 717
T+V G + + P+ G P V W K P P ++
Sbjct: 2040 TLVSRPGELVTMVCPVRGSPPIHVSWLK--------DGLPLP-------------LSQRT 2078
Query: 718 LCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAA 777
L G + + D G++T +P G N T++V VP
Sbjct: 2079 LLHGSGHT----------LRISKVQLADAGIFTCVAASPAGVADRNFTLQV-QVPPVLEP 2127
Query: 778 PKISNVGEDSCTVQW---EPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEAR 834
+ N D V+ E P G P+ WM+ L+ + +
Sbjct: 2128 VEFQN---DVVVVRGSLVELPCEARGVPL----------PLVSWMKDGEPLLSQSLEQGP 2174
Query: 835 RMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPE 894
+ V + + +S A + F EP H+ + T +SL P
Sbjct: 2175 SLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLT--VMEPPHIE-DSGQPTELSLTPGAPM 2231
Query: 895 RVGAGGLDGYSVEYCPEGCSEWVAALQGLT--EHTSILVKDLPTGARLLFRVRAHNMAGP 952
+ + P+ W Q LT E+ S + L L+ A + AG
Sbjct: 2232 ELLC------DAQGTPQPNITWHKDGQALTRLENNSRATRVLRVRDAGLYTCLAESPAGA 2285
Query: 953 GAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQ 1012
+ + V VQ P + PR R + G+ V L + +P P++TW ++G
Sbjct: 2286 ---IEKSFRVRVQA---PPNIVGPRGPRFVVGLAPGQLV-LECSVEAEPAPKITWHRDGI 2338
Query: 1013 PLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPS----- 1067
L E+ + L ++A SG Y T R +++ P+
Sbjct: 2339 VLQ-EDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGSTSVAFRVEIHTVPTIRSGP 2397
Query: 1068 PPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVP 1127
P ++ V L + P V W D ++ + + E R + P
Sbjct: 2398 PAVNVSVNQTALLPCQADGVPAPLVS----WRKDRVPLDPRSPRFEILPEGSLR---IQP 2450
Query: 1128 ELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPL 1187
L G+Y + S N G SDR + L E P+
Sbjct: 2451 VLAQDAGHYLCLAS-NSAG-SDRQG--------------------RDLRVLEPPAIAPSP 2488
Query: 1188 VNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLG---EDARFRMFSKQGVLTLEIRKPC 1244
N ++ A A+L C GSPKP + W+K+G L + +R+ +L + P
Sbjct: 2489 SNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNALL---LTAPG 2545
Query: 1245 PFDGGIYVCRATNLQGEARCECRLEVRVP 1273
P D + C +N GEA ++ V VP
Sbjct: 2546 PQDSAQFECVVSNEVGEAHRLYQVTVHVP 2574
Score = 65.5 bits (158), Expect = 3e-10
Identities = 92/348 (26%), Positives = 135/348 (38%), Gaps = 62/348 (17%)
Query: 942 FRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKP 1001
+R A N+AG +TE + PR+ LP L + V PV L G P
Sbjct: 672 YRCVASNVAG------STELRYGLRVNVPPRITLPPSLPGPVL--VNTPVRLTCNATGAP 723
Query: 1002 RPQVTWTKEGQPLAGEEV-SIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVL 1060
P + W K+G P++ ++ P +L + +AR SG Y ED+ +VL
Sbjct: 724 SPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVL 783
Query: 1061 QVVDKPSP-PQDLRVTDAWGLNVALEWK-----PP-----QDVGNTELWGYTVQKADKKT 1109
QV PS ++L V+ +VALE + PP +D E ADK
Sbjct: 784 QVHMPPSILGEELNVSVVANESVALECQSHAMPPPVLSWWKDGRPLEPRPGVHLSADKAL 843
Query: 1110 MEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTK---EPVFIPRPGIT 1166
++ V + + ++ + N G S++ PVF R T
Sbjct: 844 LQ--------------VDRADVWDAGHYTCEALNQAGHSEKHYNLNVWVAPVFPLRESHT 889
Query: 1167 YEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDL-GEDA 1225
+V G+ L C RG P PKISW K+G L GE A
Sbjct: 890 L-----------------------TVREGHPTRLSCECRGVPFPKISWRKDGQPLPGEGA 926
Query: 1226 RFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVRVP 1273
+ S G L L + + G Y C +N+ G + + +LEV VP
Sbjct: 927 GLQHVSAVGRL-LYLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVP 973
Score = 64.7 bits (156), Expect = 5e-10
Identities = 80/318 (25%), Positives = 120/318 (37%), Gaps = 59/318 (18%)
Query: 976 PRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRN-SPTDTILFIRA 1034
P T+ + G P L +G P P+++W K+GQPL GE +++ S +L++
Sbjct: 883 PLRESHTLTVREGHPTRLSCECRGVPFPKISWRKDGQPLPGEGAGLQHVSAVGRLLYLGQ 942
Query: 1035 ARRVHSGTYQ------VTVRIENMEDKATLVLQVVDKPSPPQDLRVTD--AWGLNVALEW 1086
A+ GTY V ++++ + + Q+ PP + V L
Sbjct: 943 AQLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQIAGPREPPTQVSVVQDGVATLECNATG 1002
Query: 1087 KPP---------QDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYF 1137
KPP Q VG EL G +Q + H R CV
Sbjct: 1003 KPPPTVTWERDGQPVG-AEL-GLQLQNQGQSLHVERAQAAHTGRYSCV------------ 1048
Query: 1138 RVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYT 1197
++N+ G ++R V +P P LD PL N +
Sbjct: 1049 ---AENLAGRAERKFELS--VLVP-------PELIGDLD---------PLTNITAALHSP 1087
Query: 1198 AMLCCAVRGSPKPKISWFK--NGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRA 1255
L C G P P I WF+ + GED + G L++ + D G+Y C A
Sbjct: 1088 LTLLCEAMGIPPPAIRWFRGEEPVSPGEDT----YLLAGGWMLKMTQTQEQDSGLYSCLA 1143
Query: 1256 TNLQGEARCECRLEVRVP 1273
+N GEAR +EV VP
Sbjct: 1144 SNEAGEARRNFSVEVLVP 1161
Score = 58.9 bits (141), Expect = 3e-08
Identities = 147/685 (21%), Positives = 242/685 (35%), Gaps = 120/685 (17%)
Query: 393 EVKWLKNGQEIQMSGSKYIFESIGAK-RTLTISQCSLADDAAYQCVVGGEKCSTE----L 447
+V W K Q + S ++ ++ R L I Q L+D +Y+CV STE L
Sbjct: 634 DVSWFKGHQPV----SSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASNVAGSTELRYGL 689
Query: 448 FVKEPPVLITRPLEDQLVMVGQRVEFECEVS-EEGAQVKWLKDGVELTREETFKYRFKKD 506
V PP + P V+V V C + + WLKDG ++ T +
Sbjct: 690 RVNVPPRITLPPSLPGPVLVNTPVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPG 749
Query: 507 GQRHHLIINEAMLEDAGHYA--LCTSGGQALAELIVQ-EKKLEVYQSIADLMVGAKDQAV 563
G+ L + A D+G Y+ ++ G+ ++++Q + ++ V A +
Sbjct: 750 GR--VLTLASARASDSGRYSCVAVSAVGEDRQDVVLQVHMPPSILGEELNVSVVANESVA 807
Query: 564 FKCEVSDENVRGV--WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGF 621
+C+ S V W K+G+ L P + +S + L +D D Y+
Sbjct: 808 LECQ-SHAMPPPVLSWWKDGRPLEPRPGVHLSADKAL--LQVDRADVWDAGHYTCEALNQ 864
Query: 622 ACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTV 681
A + S K + + V + V P R T+ V G+ RL G P P +
Sbjct: 865 AGH-SEKHYNLNVWVAPV-----------FPLRESHTLTVREGHPTRLSCECRGVPFPKI 912
Query: 682 IWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGA 741
W+K +P P EG + + + A
Sbjct: 913 SWRK--------DGQPLPG---------------------EGAGLQHVSAVGRLLYLGQA 943
Query: 742 EKEDEGVYTVTVKNPVGEDQVNLTVKVIDVP----------------DAPAAPKISNVGE 785
+ EG YT N VG +L ++V P D A + + G+
Sbjct: 944 QLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQIAGPREPPTQVSVVQDGVATLECNATGK 1003
Query: 786 DSCTVQWEPPAYDGGQPI---LGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVY 842
TV WE GQP+ LG L+ + + L+ + Q +H R
Sbjct: 1004 PPPTVTWE----RDGQPVGAELGLQLQNQGQS------LHVERAQ-AAHTGRYSCVAENL 1052
Query: 843 EMRVYAVNAIGMSRPSPASQPFMPI----GPPSEPTHLAVEDVSDTTVSLKWRPPERVGA 898
R + + P P+ P L E + +++W E +
Sbjct: 1053 AGRAERKFELSVLVPPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWFRGEEPVS 1112
Query: 899 GGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTT 958
G D Y + W+ + E S L L A N AG +
Sbjct: 1113 PGEDTYLL------AGGWMLKMTQTQEQDSGLYSCL-----------ASNEAGEARRNFS 1155
Query: 959 TEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEE 1018
E+L P ++ L + I+ G+ +L+ G P+P++TW K+G+PLA +
Sbjct: 1156 V------EVLVPPSIE-NEDLEEVIKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGD 1208
Query: 1019 VSIRNSPTDTILFIRAARRVHSGTY 1043
SP +L + A +G Y
Sbjct: 1209 AH-HISPDGVLLQVLQANLSSAGHY 1232
Score = 58.5 bits (140), Expect = 4e-08
Identities = 87/361 (24%), Positives = 127/361 (35%), Gaps = 48/361 (13%)
Query: 923 LTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQT 982
L E S+ + G L+ RA N AG T ++ P L Q
Sbjct: 83 LDEGQSLHFPRIQEGDSGLYSCRAENQAG-------TAQRDFHLLVLTPPSVLGAGAAQE 135
Query: 983 IQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGT 1042
+ G V L G P PQV WTK+ QP+ ++ +L I + G
Sbjct: 136 VLGLAGADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHVGDEGR 195
Query: 1043 YQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTV 1102
YQ + L+V P+ WG N E +D L
Sbjct: 196 YQCVAFSPAGQQARDFQLRVHAPPT---------IWGSNETGEVAVMEDHLVQLLC--EA 244
Query: 1103 QKADKKTMEWFTVLEHYRRTHCVV-----PELIIGNGY-----YFRVFSQNMVGFSDRAA 1152
+ + WF + VV +L +G + + N VG +++A
Sbjct: 245 RGVPTPNITWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGAAEKAT 304
Query: 1153 TTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKI 1212
Y PP + +P V ++V AG L C RG P P +
Sbjct: 305 RLD----------VYVPPTIEGAG-------GRPYVVKAV-AGRPVALECVARGHPSPTL 346
Query: 1213 SWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVRV 1272
SW GL + E R+ + VL LE P G+Y C A++ GEA + +EV+V
Sbjct: 347 SWHHEGLPVAESNESRLETDGSVLRLE--SPGEASSGLYSCVASSPAGEAVLQYSVEVQV 404
Query: 1273 P 1273
P
Sbjct: 405 P 405
Score = 50.4 bits (119), Expect = 1e-05
Identities = 95/445 (21%), Positives = 154/445 (34%), Gaps = 94/445 (21%)
Query: 369 LEPAYQVSKGHKIRLTVELADH-DAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCS 427
LE +V G L + H ++ W K+G+ + + +I L + Q +
Sbjct: 1169 LEEVIKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHHISPD---GVLLQVLQAN 1225
Query: 428 LADDAAYQCVVG---GEKCST-ELFVKEPPVLI----TRPLEDQLVMVGQRVEFECE-VS 478
L+ Y C+ GEK +L V P ++ E+ V V + CE ++
Sbjct: 1226 LSSAGHYSCIAANAVGEKTKHFQLSVLLAPTILGGAEDSADEEVTVTVNNPISLICEALA 1285
Query: 479 EEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSG--GQA-- 534
+ W+KDG + H L I A EDAG Y + G+A
Sbjct: 1286 FPSPNITWMKDGAPFEASRNIQLL----PGTHGLQILNAQKEDAGQYTCVVTNELGEAVK 1341
Query: 535 -----------------LAELIVQEKKLEVYQSIADLMVGAKDQAVFKCE---VSDENVR 574
LAE+ V+E K +V ++ +CE V +R
Sbjct: 1342 NYHVEVLIPPSISKDDPLAEVGVKEVKTKVNSTLT-----------LECESWAVPPPTIR 1390
Query: 575 GVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFA------CNLSAK 628
W K+G+ + P SR++V GR+ L I +D Y V A N+ +
Sbjct: 1391 --WYKDGQPVTPSSRLQVLGEGRL--LQIQPTQVSDSGRYLCVATNVAGEDDQDFNVLIQ 1446
Query: 629 LHFMEVKI-DFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAI 687
+ M K+ DF E + G + + +V N L + P P + W +
Sbjct: 1447 VPPMFQKVGDFSAAFEILSREEEARGGVTEYREIVENNPAYLYCDTNAIPPPDLTWYR-- 1504
Query: 688 TQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEG 747
D P GD V + + + E+ G
Sbjct: 1505 -----------EDQPLSAGD------------------EVSVLQGGRVLQIPLVRAENAG 1535
Query: 748 VYTVTVKNPVGEDQVNLTVKVIDVP 772
Y+ N VGED ++ + V+ P
Sbjct: 1536 RYSCKASNEVGEDWLHYELLVLTPP 1560
Score = 46.6 bits (109), Expect = 2e-04
Identities = 32/80 (40%), Positives = 41/80 (51%), Gaps = 4/80 (5%)
Query: 1192 VIAGYTAMLCCAVRGSPKPKISWFKNGLDLGE-DARFRMFSKQGVLTLEIRKPCPFDGGI 1250
V+ G TA L C V G P+PK++WFK+G L DA S GVL L++ + G
Sbjct: 1175 VLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHH--ISPDGVL-LQVLQANLSSAGH 1231
Query: 1251 YVCRATNLQGEARCECRLEV 1270
Y C A N GE +L V
Sbjct: 1232 YSCIAANAVGEKTKHFQLSV 1251
Score = 45.8 bits (107), Expect = 3e-04
Identities = 30/93 (32%), Positives = 41/93 (44%), Gaps = 4/93 (4%)
Query: 1181 PSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDL-GEDARFRMFSKQGVLTLE 1239
P L + S G A L C RGSP+P I+W K+G + G + +F + +L
Sbjct: 2756 PVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKN 2815
Query: 1240 IRKPCPFDGGIYVCRATNLQGEARCECRLEVRV 1272
+ D G Y C A N G AR L + V
Sbjct: 2816 LEGQ---DAGTYTCTAENAVGRARRRVHLTILV 2845
Score = 45.1 bits (105), Expect = 4e-04
Identities = 31/88 (35%), Positives = 42/88 (47%), Gaps = 4/88 (4%)
Query: 1186 PLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCP 1245
P V R+V A +L C G P+P I+W K GL++ ++ L I P
Sbjct: 2672 PSVVRAV-AEEEVLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPGG---QLRIAHASP 2727
Query: 1246 FDGGIYVCRATNLQGEARCECRLEVRVP 1273
D G Y+C A N G A + RL V+VP
Sbjct: 2728 EDAGNYLCIAKNSAGSAMGKTRLVVQVP 2755
Score = 43.5 bits (101), Expect = 0.001
Identities = 95/442 (21%), Positives = 159/442 (35%), Gaps = 85/442 (19%)
Query: 393 EVKWLKNGQEI----------------QMSGSKYIFESIGAKRTLTISQCSLADDAAYQC 436
E+ WLK+ Q + Q+ G + + E ++L + D Y C
Sbjct: 49 EIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEG----QSLHFPRIQEGDSGLYSC 104
Query: 437 ----VVGGEKCSTELFVKEPP-VLITRPLEDQLVMVGQRVEFECEVSEEGA-QVKWLKDG 490
G + L V PP VL ++ L + G VE +C S QV+W KD
Sbjct: 105 RAENQAGTAQRDFHLLVLTPPSVLGAGAAQEVLGLAGADVELQCWTSGVPTPQVEWTKDR 164
Query: 491 VELTREETFKYRFKKDGQRHHLIINEAMLEDAGHY---ALCTSGGQALAELIVQEKKLEV 547
+ + ++DGQ L I + + D G Y A +G QA + +
Sbjct: 165 QPVLPGGPH-LQVQEDGQV--LRITGSHVGDEGRYQCVAFSPAGQQARDFQLRVHAPPTI 221
Query: 548 YQSIADLMVGAKDQAVFK--CEVSDENVRGV-WLKNGKELVPDSRIKVSHIGRVHKLTID 604
+ S V + + + CE + W K+G L +++ + GR +L +
Sbjct: 222 WGSNETGEVAVMEDHLVQLLCEARGVPTPNITWFKDGALLPTSTKVVYTRGGR--QLQLG 279
Query: 605 DVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAG 664
+D Y+ A + K ++V + PP I + G P + VAG
Sbjct: 280 RAQSSDAGVYTCKASN-AVGAAEKATRLDVYV-------PPTI--EGAGGRPYVVKAVAG 329
Query: 665 NKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGR 724
+ L+ G P+PT+ W P ++ E
Sbjct: 330 RPVALECVARGHPSPTLSWHH--------EGLPVAESNES-------------------- 361
Query: 725 VRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPKISNVG 784
R+ET D S+ +E + G+Y+ +P GE + +V+V P A + V
Sbjct: 362 -RLET--DGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSVEVQVPPQLLVAEGLGQV- 417
Query: 785 EDSCTVQWEP---PAYDGGQPI 803
T+ +P P G P+
Sbjct: 418 ---TTIVGQPLELPCQASGSPV 436
Score = 42.0 bits (97), Expect = 0.004
Identities = 184/895 (20%), Positives = 291/895 (32%), Gaps = 154/895 (17%)
Query: 421 LTISQCSLADDAAYQC----VVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECE 476
L I + L D+ Y C + G K L V PP + P+ ++ V+ V EC
Sbjct: 568 LQIEKVDLRDEGIYTCAATNLAGESKREVALKVLVPPNIEPGPV-NKAVLENASVTLECL 626
Query: 477 VSE-EGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQAL 535
S V W K ++ DG+ L I +A L DAG Y S
Sbjct: 627 ASGVPPPDVSWFKGHQPVS--SWMGVTVSVDGRV--LRIEQAQLSDAGSYRCVASNVAGS 682
Query: 536 AEL-----IVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSR- 589
EL + ++ + S+ ++ + + +WLK+G + P
Sbjct: 683 TELRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTCNATGAPSPTLMWLKDGNPVSPAGTP 742
Query: 590 -IKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIH 648
++V GRV LT+ +D YS V A E + D V + P
Sbjct: 743 GLQVFPGGRV--LTLASARASDSGRYSCV---------AVSAVGEDRQDVVLQVHMP--- 788
Query: 649 LDCPGRIPD--TIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTG 706
P + + + VVA + L+ P P + W K + P P P
Sbjct: 789 ---PSILGEELNVSVVANESVALECQSHAMPPPVLSWWK-----DGRPLEPRPG------ 834
Query: 707 DSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTV 766
V + D+++ V+ A+ D G YT N G + + +
Sbjct: 835 --------------------VHLSADKALLQVDRADVWDAGHYTCEALNQAGHSEKHYNL 874
Query: 767 KVIDVPDAPAAPKISNVGED------SCTVQWEP-PAYD---GGQPILGYILERKKKKSY 816
V P P + + SC + P P GQP+ G + +
Sbjct: 875 NVWVAPVFPLRESHTLTVREGHPTRLSCECRGVPFPKISWRKDGQPLPGEGAGLQHVSAV 934
Query: 817 RWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMP---IGPPSEP 873
RL + +L+ E E N +G S + +P GP P
Sbjct: 935 G--RLLYLGQAQLAQEGTYTCE---------CSNVVGNSSQDLQLEVHVPPQIAGPREPP 983
Query: 874 THLAV--EDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILV 931
T ++V + V+ + +PP V DG P G LQ + S+ V
Sbjct: 984 TQVSVVQDGVATLECNATGKPPPTV-TWERDGQ-----PVGAE---LGLQLQNQGQSLHV 1034
Query: 932 KDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPV 991
+ + A N+AG E +L P L I + P+
Sbjct: 1035 ERAQAAHTGRYSCVAENLAG------RAERKFELSVLVPPELIGDLDPLTNITAALHSPL 1088
Query: 992 NLLIPFQGKPRPQVTWTKEGQPLA-GEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIE 1050
LL G P P + W + +P++ GE+ + +L + + SG Y E
Sbjct: 1089 TLLCEAMGIPPPAIRWFRGEEPVSPGEDTYLLAG--GWMLKMTQTQEQDSGLYSCLASNE 1146
Query: 1051 NMEDKATLVLQVVDKPSPPQD-----LRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKA 1105
E + ++V+ PS + ++V D G T V
Sbjct: 1147 AGEARRNFSVEVLVPPSIENEDLEEVIKVLD----------------GQTAHLMCNVTGH 1190
Query: 1106 DKKTMEWFTVLEHYRR--THCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRP 1163
+ + WF R H + P+ G +V N+ + V
Sbjct: 1191 PQPKLTWFKDGRPLARGDAHHISPD-----GVLLQVLQANLSSAGHYSCIAANAVG---- 1241
Query: 1164 GITYEPPNYKALDFSEAPSFTQPLVNRS-----VIAGYTAMLCCAVRGSPKPKISWFKNG 1218
E + L AP+ + + V L C P P I+W K+G
Sbjct: 1242 ----EKTKHFQLSVLLAPTILGGAEDSADEEVTVTVNNPISLICEALAFPSPNITWMKDG 1297
Query: 1219 LDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVRVP 1273
++ G L+I D G Y C TN GEA +EV +P
Sbjct: 1298 APFEASRNIQLLP--GTHGLQILNAQKEDAGQYTCVVTNELGEAVKNYHVEVLIP 1350
Score = 41.2 bits (95), Expect = 0.006
Identities = 29/80 (36%), Positives = 37/80 (46%), Gaps = 2/80 (2%)
Query: 1191 SVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGI 1250
+ I G L C GSP P I W +NG E A ++ S QG TL I G+
Sbjct: 418 TTIVGQPLELPCQASGSPVPTIQWLQNGRPAEELAGVQVAS-QGT-TLHIDHVELDHSGL 475
Query: 1251 YVCRATNLQGEARCECRLEV 1270
+ C+ATN G A E + V
Sbjct: 476 FACQATNEAGTAGAEVEVSV 495
Score = 41.2 bits (95), Expect = 0.006
Identities = 40/146 (27%), Positives = 61/146 (41%), Gaps = 9/146 (6%)
Query: 956 VTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLA 1015
V T+ V+ + + P LQ + + VG + L +G P P + W K+G PL
Sbjct: 2921 VGRTQAVSFVHVKEAPVLQ--GEAFSYLVEPVGGSIQLDCVVRGDPVPDIHWIKDGLPLR 2978
Query: 1016 GEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKP---SPPQDL 1072
G +R+ + L IR R +G YQ E K ++L + P PQD+
Sbjct: 2979 GSH--LRHQLQNGSLTIRRTERDDAGRYQCLAENEMGVAKKVVILVLQSAPVFQVEPQDM 3036
Query: 1073 RVTDAWGLNVALEWKPPQDVGNTELW 1098
V G +VAL + + T W
Sbjct: 3037 TVRS--GDDVALRCQATGEPTPTIEW 3060
Score = 40.8 bits (94), Expect = 0.008
Identities = 79/347 (22%), Positives = 125/347 (36%), Gaps = 45/347 (12%)
Query: 941 LFRVRAHNMAGPGAPVTTTE---PVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPF 997
++ +A N G T + P T++ RP + ++ G PV L
Sbjct: 288 VYTCKASNAVGAAEKATRLDVYVPPTIEGAGGRPYV---------VKAVAGRPVALECVA 338
Query: 998 QGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKAT 1057
+G P P ++W EG P+A E R ++L + + SG Y
Sbjct: 339 RGHPSPTLSWHHEGLPVA-ESNESRLETDGSVLRLESPGEASSGLYSCVA----SSPAGE 393
Query: 1058 LVLQVVDKPSPPQDLRVTDAWGLNVALEWKP---PQDVGNTELWGYTVQKADKKTMEWFT 1114
VLQ + P L V + G + +P P + + + + E
Sbjct: 394 AVLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWLQNGRPAEELAG 453
Query: 1115 VLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIP---RPGITYEP-- 1169
V + T + + + + F + N G A + V + PG+ P
Sbjct: 454 VQVASQGTTLHIDHVELDHSGLFACQATNEAG----TAGAEVEVSVHGEWAPGVLEVPIG 509
Query: 1170 -PNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKI--SWFKNGLDLGEDAR 1226
++ S P+ P V+R G+ A PKP + W G GE
Sbjct: 510 QYHWGXEHHSSFPAACDPPVHR----GWGA--------HPKPPLVEGWCSPGSLWGEPTG 557
Query: 1227 FRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVRVP 1273
+ + L+I K D GIY C ATNL GE++ E L+V VP
Sbjct: 558 IPV-AYSLPPPLQIEKVDLRDEGIYTCAATNLAGESKREVALKVLVP 603
Score = 39.7 bits (91), Expect = 0.019
Identities = 33/97 (34%), Positives = 38/97 (39%), Gaps = 3/97 (3%)
Query: 1175 LDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQG 1234
L AP F + +V +G L C G P P I W + G L R R G
Sbjct: 3021 LVLQSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTL-PDG 3079
Query: 1235 VLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVR 1271
L LE + D G Y C A NL G A L VR
Sbjct: 3080 SLWLENVE--TGDAGTYDCVAHNLLGSATARAFLVVR 3114
Score = 35.4 bits (80), Expect = 0.35
Identities = 64/306 (20%), Positives = 112/306 (36%), Gaps = 36/306 (11%)
Query: 391 DAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCV----VGGEKCSTE 446
+ + W K+GQ + + K+ + G L + D Y C VG +
Sbjct: 2784 EPNITWDKDGQPVSGAEGKFTIQPSGE---LLVKNLEGQDAGTYTCTAENAVGRARRRVH 2840
Query: 447 LFVKEPPVLITRPLEDQLVMVGQRVEFECEV-SEEGAQVKWLKDGVELTREETFKYRFKK 505
L + PV T P D+ + +G R+ C ++ W + +T + ++
Sbjct: 2841 LTILVLPVFTTLP-GDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEGVS-----EQ 2894
Query: 506 DGQRHHLIINEAMLEDAGHYALCTSG--GQALAELIVQEKKLEVYQ--SIADLMVGAKDQ 561
DG L ED+G Y G+ A V K+ V Q + + L+
Sbjct: 2895 DGGST-LQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVKEAPVLQGEAFSYLVEPVGGS 2953
Query: 562 AVFKCEVSDENVRGV-WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEG 620
C V + V + W+K+G +P + H + LTI D Y + E
Sbjct: 2954 IQLDCVVRGDPVPDIHWIKDG---LPLRGSHLRHQLQNGSLTIRRTERDDAGRYQCLAEN 3010
Query: 621 FACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPT 680
+ K+ + Q P ++ P + V +G+ + L +G+P PT
Sbjct: 3011 EMG--------VAKKVVILVLQSAPVFQVE-----PQDMTVRSGDDVALRCQATGEPTPT 3057
Query: 681 VIWQKA 686
+ W +A
Sbjct: 3058 IEWLQA 3063
Score = 34.3 bits (77), Expect = 0.78
Identities = 30/100 (30%), Positives = 42/100 (42%), Gaps = 17/100 (17%)
Query: 1189 NRSVIAGYTAMLCCAVRGSPKPKISWFKN-------------GLDL--GEDARFRMFSKQ 1233
N S +AG + L C G P P+I W K+ G DL G+ R+ +
Sbjct: 27 NVSGMAGQSLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEG 86
Query: 1234 GVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVRVP 1273
+L + D G+Y CRA N G A+ + L V P
Sbjct: 87 --QSLHFPRIQEGDSGLYSCRAENQAGTAQRDFHLLVLTP 124
Score = 34.3 bits (77), Expect = 0.78
Identities = 91/451 (20%), Positives = 159/451 (35%), Gaps = 101/451 (22%)
Query: 394 VKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVV----GGEKCSTELFV 449
V W ++GQ + G++ + ++L + + A Y CV G + EL V
Sbjct: 1008 VTWERDGQPV---GAELGLQLQNQGQSLHVERAQAAHTGRYSCVAENLAGRAERKFELSV 1064
Query: 450 KEPPVLI--TRPLEDQLVMVGQRVEFECE-VSEEGAQVKWLKDGVELTR-EETFKYRFKK 505
PP LI PL + + + CE + ++W + ++ E+T+
Sbjct: 1065 LVPPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWFRGEEPVSPGEDTYLL---- 1120
Query: 506 DGQRHHLIINEAMLEDAGHYALCTSG--GQA-----LAELIVQEKKLEVYQSIADLMVGA 558
L + + +D+G Y+ S G+A + L+ + E + + ++ G
Sbjct: 1121 -AGGWMLKMTQTQEQDSGLYSCLASNEAGEARRNFSVEVLVPPSIENEDLEEVIKVLDG- 1178
Query: 559 KDQAVFKCEVSDE-NVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFV 617
A C V+ + W K+G+ L G H ++ D V +
Sbjct: 1179 -QTAHLMCNVTGHPQPKLTWFKDGRPLAR---------GDAHHISPDGV----------L 1218
Query: 618 PEGFACNLSAKLHFMEVKIDFVPRQEP---------PKIHLDCPGRIPDTIVVVAGNKLR 668
+ NLS+ H+ + + V + P I + + V N +
Sbjct: 1219 LQVLQANLSSAGHYSCIAANAVGEKTKHFQLSVLLAPTILGGAEDSADEEVTVTVNNPIS 1278
Query: 669 LDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVE 728
L P+P + W K + AP + + +LL T G
Sbjct: 1279 LICEALAFPSPNITWMK-----DGAPFEASRNI--------------QLLPGTHG----- 1314
Query: 729 TTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPKISNVG---- 784
+ A+KED G YT V N +GE N V+V+ P ++ VG
Sbjct: 1315 -------LQILNAQKEDAGQYTCVVTNELGEAVKNYHVEVLIPPSISKDDPLAEVGVKEV 1367
Query: 785 ----EDSCTVQWE-----PPA---YDGGQPI 803
+ T++ E PP Y GQP+
Sbjct: 1368 KTKVNSTLTLECESWAVPPPTIRWYKDGQPV 1398
Score = 30.8 bits (68), Expect = 8.6
Identities = 19/63 (30%), Positives = 29/63 (46%), Gaps = 2/63 (3%)
Query: 981 QTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHS 1040
Q + + G+ V L G+P P + W + GQPL +R P D L++ +
Sbjct: 3034 QDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASR-RLRTLP-DGSLWLENVETGDA 3091
Query: 1041 GTY 1043
GTY
Sbjct: 3092 GTY 3094
>gi|116008194 myosin light chain kinase isoform 3A [Homo sapiens]
Length = 1863
Score = 107 bits (266), Expect = 9e-23
Identities = 200/919 (21%), Positives = 325/919 (35%), Gaps = 153/919 (16%)
Query: 4 PGKKPVSAFSKKPRSVEVAAGSPAVFEAETE-RAGVKVRWQRGGSDISASNKYGLATEGT 62
P K F + ++V GS + +V W G++I S + GT
Sbjct: 617 PSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGT 676
Query: 63 RHTLTVREVGPADQGSYAVIAGSSKVKFDLKVIEAEKAEPMLAPAPAPAEATGAPGEAPA 122
+H+L ++EV P D G+Y EA + GE
Sbjct: 677 QHSLCIQEVFPEDTGTYT------------------------------CEAWNSAGEV-- 704
Query: 123 PAAELGESAPSPKGSSSAALNGPTPGAPDDPIGLFVMRPQDGEVTVGGSITFSARVAGAS 182
+ A L P P F+ +P+ ++G S+ S +AG
Sbjct: 705 --------------RTQAVLTVQEPHDGTQP--WFISKPRSVTASLGQSVLISCAIAGDP 748
Query: 183 LLKPPVVKWFK-GKWVDLSSKVGQHLQLHDSYDRASKVYLFELHITDAQPAFTGSYRCEV 241
P V W + GK + + + LQ D +F L + QP G Y E+
Sbjct: 749 F---PTVHWLRDGKALCKDTGHFEVLQNED---------VFTLVLKKVQPWHAGQY--EI 794
Query: 242 STKDKF-DCSNFNLTVHEAMGTGDLDLLSAFRRTS----LAGGGRRISDSHEDTGILDFS 296
K++ +CS V + L R + L GGG D +
Sbjct: 795 LLKNRVGECS---CQVSLMLQNSSARALPRGREPASCEDLCGGGVGADGGGSDR----YG 847
Query: 297 SLLKKRDSFRTPRDSKLEAPAEEDVWEILRQAPPS-----------EYERIAFQYGVTDL 345
SL R + LE EDV +L++ + E E++ F+ DL
Sbjct: 848 SL---RPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFR----DL 900
Query: 346 RGMLKRLKGMRRDEKKSTAFQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQM 405
G K + D+ K PA Q+ ++ V+ E + + + Q++
Sbjct: 901 LGKKVSTKTLSEDDLKEI-------PAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDF 953
Query: 406 SGSKYIFESIGAKRTLTISQCSLADDAA--YQCVVGGEK-CSTELFVKEPPVLITRPLED 462
+ + G +T + A ++ V+GG+K E L + +E
Sbjct: 954 ---RSVLAKKGTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVES 1010
Query: 463 QLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFK-KDGQRHHLIINEAMLED 521
+ + + + LK ET K K + E + +D
Sbjct: 1011 SKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKD 1070
Query: 522 AGHYALCTSGGQALAELIVQEKKLEVY-------QSIADLMVGAKDQAVFKCEVS-DENV 573
+ C G + EK+ E Q + D+ V + + +C+VS D
Sbjct: 1071 VKNDVNCKRGHAGTTD---NEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPA 1127
Query: 574 RGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFME 633
+W NGK L I +S G + ++I+ P D Y V + A +
Sbjct: 1128 TIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSC---Q 1184
Query: 634 VKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKA 693
V +D P E K R ++ V G + D + PAP T A
Sbjct: 1185 VTVDDAPASENTKAPEMKSRRPKSSLPPVLGTES--DATVKKKPAPK-------TPPKAA 1235
Query: 694 PARPAPDAPED----TGDSDE--------------WVFDKKLLCETEGRVRVETTKDRSI 735
PED G+S E W+ +K + E+E ++VE +++ S
Sbjct: 1236 MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESE-HMKVENSENGSK 1294
Query: 736 FTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPA-APKISNVGEDSCTVQWEP 794
T+ A +E G YT+ V+N +G Q + + V+D PD PA P S++ S T+ W
Sbjct: 1295 LTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYG 1354
Query: 795 PAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGM 854
+YDGG + Y +E + W L + S + ++ Y+ RV A+N G
Sbjct: 1355 SSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYKFRVRAINVYGT 1412
Query: 855 SRPSPASQPFMPIGPPSEP 873
S PS S+ P EP
Sbjct: 1413 SEPSQESELTTVGEKPEEP 1431
Score = 65.9 bits (159), Expect = 2e-10
Identities = 93/402 (23%), Positives = 139/402 (34%), Gaps = 78/402 (19%)
Query: 393 EVKWLKNGQEIQ-MSGSKYIFESIGAKRTLTISQCSLADDAAYQCVV----GGEKCSTEL 447
EV W G ++ GS ++E G+ L + + D Y C G CS L
Sbjct: 444 EVAWFLEGTPVRRQEGSIEVYEDAGS-HYLCLLKARTRDSGTYSCTASNAQGQLSCSWTL 502
Query: 448 FVKEPPVLITRP-----LEDQLVMVGQRVEFECEVSEEGA-QVKWLKDGVELTREETFKY 501
V+ V+ P L+D V+ GQ +C V ++ WL +G + +Y
Sbjct: 503 QVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNG------QPIQY 556
Query: 502 -RFKKDGQRHHLIINEAMLEDAGHYALCTSGG----QALAELIVQEKKLE---------- 546
R + L I +A+ ED G Y A + V EKK
Sbjct: 557 ARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVA 616
Query: 547 --------VYQSIADLMVGAKDQAVFKCEVS-DENVRGVWLKNGKELVPDSRIKVSHIGR 597
Q ++DL V Q +VS + +WL NG E+ G
Sbjct: 617 PSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGT 676
Query: 598 VHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPD 657
H L I +V P D Y+ A N + ++ V + QEP P
Sbjct: 677 QHSLCIQEVFPEDTGTYTCE----AWNSAGEVRTQAV----LTVQEPHDGTQPWFISKPR 728
Query: 658 TIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKL 717
++ G + + I+GDP PTV W+ D K
Sbjct: 729 SVTASLGQSVLISCAIAGDPFPTV----------------------------HWLRDGKA 760
Query: 718 LCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGE 759
LC+ G V +D ++ + G Y + +KN VGE
Sbjct: 761 LCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE 802
Score = 62.0 bits (149), Expect = 3e-09
Identities = 80/327 (24%), Positives = 133/327 (40%), Gaps = 54/327 (16%)
Query: 461 EDQLVMVGQRVEFECEVSE-EGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAML 519
+ Q V Q V+F CEVS +V W +G + R+E +D H+L + +A
Sbjct: 421 QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEG-SIEVYEDAGSHYLCLLKART 479
Query: 520 EDAGHYALCTSG---GQALAELIVQEKKLEVYQSIADLMVGAKDQA-------VFKCEVS 569
D+G Y+ CT+ GQ +Q ++L V + KD A V +C V
Sbjct: 480 RDSGTYS-CTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVR 538
Query: 570 DENV-RGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEG----FACN 624
V R WL NG+ P + + V +L I D P D Y+ + E +C+
Sbjct: 539 GTPVPRITWLLNGQ---PIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCS 595
Query: 625 LSAKLHFMEV--KIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVI 682
+H + K +++ P K + + V+ G+++ + V +SG+P P VI
Sbjct: 596 AWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVI 655
Query: 683 WQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAE 742
W + GN + +S+++ F+++ + ++
Sbjct: 656 W---LHNGN------------EIQESEDFHFEQR--------------GTQHSLCIQEVF 686
Query: 743 KEDEGVYTVTVKNPVGE--DQVNLTVK 767
ED G YT N GE Q LTV+
Sbjct: 687 PEDTGTYTCEAWNSAGEVRTQAVLTVQ 713
Score = 61.6 bits (148), Expect = 5e-09
Identities = 73/311 (23%), Positives = 119/311 (38%), Gaps = 34/311 (10%)
Query: 981 QTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIR--NSPTDTILFIRAARRV 1038
Q+ + K + V G P+P+V W EG P+ +E SI L + AR
Sbjct: 421 QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTR 480
Query: 1039 HSGTYQVTVRIENMEDKATLVLQV----VDKPSPP-----QDLRVTDA--WGLNVALEWK 1087
SGTY T + + LQV V + +P +D V + + L ++
Sbjct: 481 DSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGT 540
Query: 1088 PPQDV-----GNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQ 1142
P + G + + +A + L T+ + E +G +V
Sbjct: 541 PVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALG-----QVSCS 595
Query: 1143 NMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCC 1202
V ++ ++ K +P + P AP F Q L + V+ G +
Sbjct: 596 AWVTVHEKKSSRKSEYLLP---VAPSKPT--------APIFLQGLSDLKVMDGSQVTMTV 644
Query: 1203 AVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEA 1262
V G+P P++ W NG ++ E F + +L I++ P D G Y C A N GE
Sbjct: 645 QVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEV 704
Query: 1263 RCECRLEVRVP 1273
R + L V+ P
Sbjct: 705 RTQAVLTVQEP 715
Score = 61.6 bits (148), Expect = 5e-09
Identities = 57/198 (28%), Positives = 82/198 (41%), Gaps = 12/198 (6%)
Query: 954 APVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTK-EGQ 1012
AP T + +I+Q P Q R GE V L G TW K Q
Sbjct: 1227 APKTPPKAAMPPQIIQFPEDQKVR---------AGESVELFGKVTGTQPITCTWMKFRKQ 1277
Query: 1013 PLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDL 1072
E + + NS + L I AAR+ H G Y + V + +A + L VVDKP PP
Sbjct: 1278 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGT 1337
Query: 1073 R-VTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELII 1131
+D ++ L W G + + Y+++ D W L R T V +L+
Sbjct: 1338 PCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTW-KELATCRSTSFNVQDLLP 1396
Query: 1132 GNGYYFRVFSQNMVGFSD 1149
+ Y FRV + N+ G S+
Sbjct: 1397 DHEYKFRVRAINVYGTSE 1414
Score = 57.0 bits (136), Expect = 1e-07
Identities = 34/112 (30%), Positives = 53/112 (47%), Gaps = 1/112 (0%)
Query: 1160 IPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGL 1219
I + ++ +P ++ +EAP+F P N + G TA VRG P+P+++W +NG
Sbjct: 12 ISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQ 71
Query: 1220 DLGEDARFRM-FSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
+ RF + +G +L I D G Y C ATN G + L V
Sbjct: 72 PITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
Score = 57.0 bits (136), Expect = 1e-07
Identities = 104/493 (21%), Positives = 172/493 (34%), Gaps = 90/493 (18%)
Query: 85 SSKVKFDLKVIEAEKAEP---MLAPAPAPAEATGAPGEAPAPAAELGESAPSPKGSSSAA 141
SS + ++ E P +L+P+ + P A P + G + S +A
Sbjct: 342 SSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVV-SKAAN 400
Query: 142 LNGPTPGAPDDPIGLFVMRPQDGEVTVGGSITFSARVAGASLLKPPVVKWFKGKWVDLSS 201
P G D F +PQ EV ++ F V+G + P V WF +
Sbjct: 401 RRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSG---IPKPEVAWFLE-----GT 452
Query: 202 KVGQHLQLHDSYDRASKVYLFELHITDAQPAFTGSYRCEVSTKDKFDCSNFNLTVHEAMG 261
V + + Y+ A YL + A+ +G+Y C T A G
Sbjct: 453 PVRRQEGSIEVYEDAGSHYLC---LLKARTRDSGTYSC---------------TASNAQG 494
Query: 262 TGDLDLLSAFRRTSLAGGGRRISDSHEDTGILDFSSLLKKRDSFRTPRDSKLEAPAEEDV 321
R ++ S +D +++ + + S P
Sbjct: 495 QLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL--------QCSVRGTPVPRIT 546
Query: 322 WEILRQAPPSEYERIAFQYGVTDLR--------------------GMLKRLKGMRRDEKK 361
W L P +Y R + GV +L G + + EKK
Sbjct: 547 W--LLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKK 604
Query: 362 STAFQKKLEPA----------------YQVSKGHKIRLTVELADH-DAEVKWLKNGQEIQ 404
S+ + L P +V G ++ +TV+++ + EV WL NG EIQ
Sbjct: 605 SSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQ 664
Query: 405 MSGSKYIFESIGAKRTLTISQCSLADDAAYQC----VVGGEKCSTELFVKEP-----PVL 455
S + FE G + +L I + D Y C G + L V+EP P
Sbjct: 665 ES-EDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWF 723
Query: 456 ITRPLEDQLVMVGQRVEFECEVS-EEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLII 514
I++P +GQ V C ++ + V WL+DG L + +T + ++ L++
Sbjct: 724 ISKP-RSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCK-DTGHFEVLQNEDVFTLVL 781
Query: 515 NEAMLEDAGHYAL 527
+ AG Y +
Sbjct: 782 KKVQPWHAGQYEI 794
Score = 57.0 bits (136), Expect = 1e-07
Identities = 34/92 (36%), Positives = 48/92 (52%), Gaps = 2/92 (2%)
Query: 1180 APSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVL-TL 1238
AP+F Q L + V G +L C V P I W NG L + +F + S++G L ++
Sbjct: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTL-KTTKFIILSQEGSLCSV 1155
Query: 1239 EIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
I K P D G+Y C A N G+A C C++ V
Sbjct: 1156 SIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1187
Score = 56.6 bits (135), Expect = 1e-07
Identities = 29/91 (31%), Positives = 45/91 (49%), Gaps = 1/91 (1%)
Query: 1181 PSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRM-FSKQGVLTLE 1239
P F++ + + V+ G A C + G P P++ WFK+ + E F++ + + G +L
Sbjct: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
Query: 1240 IRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
I C D Y C+A N GEA C L V
Sbjct: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
Score = 54.7 bits (130), Expect = 6e-07
Identities = 75/309 (24%), Positives = 123/309 (39%), Gaps = 55/309 (17%)
Query: 988 GEPVNLLIPFQGKPRPQVTWTKEGQPL--------AG-EEVSIRNS-PTD----TILFIR 1033
G+ L +G P P++TW GQP+ AG E+ I+++ P D T L
Sbjct: 528 GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAEN 587
Query: 1034 AARRVHSGTYQVTVRIENMEDKATLVLQVV-DKPSPP------QDLRVTDAWG--LNVAL 1084
A +V + VTV + K+ +L V KP+ P DL+V D + V +
Sbjct: 588 ALGQVSCSAW-VTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQV 646
Query: 1085 EWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNM 1144
PP +V +W + + + E F + + + E+ + + + N
Sbjct: 647 SGNPPPEV----IWLHNGNEIQES--EDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNS 700
Query: 1145 VGF--SDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIA--GYTAML 1200
G + T +EP +P +P RSV A G + ++
Sbjct: 701 AGEVRTQAVLTVQEPHDGTQPWFISKP--------------------RSVTASLGQSVLI 740
Query: 1201 CCAVRGSPKPKISWFKNGLDLGED-ARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQ 1259
CA+ G P P + W ++G L +D F + + V TL ++K P+ G Y N
Sbjct: 741 SCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRV 800
Query: 1260 GEARCECRL 1268
GE C+ L
Sbjct: 801 GECSCQVSL 809
Score = 52.8 bits (125), Expect = 2e-06
Identities = 33/115 (28%), Positives = 45/115 (39%), Gaps = 10/115 (8%)
Query: 1157 PVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFK 1216
P RP I E P P F L V G C + G P+P+++W K
Sbjct: 147 PAVETRPSIWGECP----------PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLK 196
Query: 1217 NGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVR 1271
+ L AR + K G+ LEI D G+Y C N G+A L ++
Sbjct: 197 GNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251
Score = 49.3 bits (116), Expect = 2e-05
Identities = 28/94 (29%), Positives = 42/94 (44%), Gaps = 1/94 (1%)
Query: 1178 SEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDL-GEDARFRMFSKQGVL 1236
S P F ++ V T C V G PKP+++WF G + ++ ++ G
Sbjct: 411 SAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSH 470
Query: 1237 TLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
L + K D G Y C A+N QG+ C L+V
Sbjct: 471 YLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQV 504
Score = 46.2 bits (108), Expect = 2e-04
Identities = 80/367 (21%), Positives = 123/367 (33%), Gaps = 98/367 (26%)
Query: 661 VVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCE 720
V G KL L +S DP T+IW T + K ++
Sbjct: 1109 VAEGKKLLLQCQVSSDPPATIIW---------------------TLNGKTLKTTKFIILS 1147
Query: 721 TEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVP--DAPAAP 778
EG + ++E A ED G+Y KN G+ + + V V D P + AP
Sbjct: 1148 QEGSL--------CSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAP 1199
Query: 779 KISN----------VGEDSCTVQWEPPA-------------------------------- 796
++ + +G +S + PA
Sbjct: 1200 EMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFG 1259
Query: 797 -YDGGQPIL-GYILERKKKKSYRWMRL-NFDLIQELSHEARRMIEGVVYEM--------R 845
G QPI ++ RK+ + M++ N + +L+ A R Y + R
Sbjct: 1260 KVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSR 1319
Query: 846 VYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYS 905
VN + +P P P G P D+ ++++L W G + YS
Sbjct: 1320 QAQVNLTVVDKPDP------PAGTP------CASDIRSSSLTLSWYGSSYDGGSAVQSYS 1367
Query: 906 VEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQ 965
+E W TS V+DL FRVRA N+ G P +E TV
Sbjct: 1368 IEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG 1425
Query: 966 EILQRPR 972
E + P+
Sbjct: 1426 EKPEEPK 1432
Score = 44.3 bits (103), Expect = 8e-04
Identities = 85/394 (21%), Positives = 144/394 (36%), Gaps = 71/394 (18%)
Query: 711 WVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVID 770
W + + EG + V + A D G Y+ T N G+ + T++V
Sbjct: 447 WFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVER 506
Query: 771 VPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELS 830
+ AP S+V +D + +G +L + W+ LN IQ
Sbjct: 507 LAVMEVAPSFSSVLKDCAVI-------EGQDFVLQCSVRGTPVPRITWL-LNGQPIQ--- 555
Query: 831 HEARRMIEGVVYEMRV-------------YAVNAIGM-----------SRPSPASQPFMP 866
AR E V E+ + A NA+G + S S+ +P
Sbjct: 556 -YARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLP 614
Query: 867 IGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGC----SEWVAALQG 922
+ P + ++ +SD V + V G V + G SE Q
Sbjct: 615 VAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQR 674
Query: 923 LTEHTSILVKDLP--TGARLLFRVRAHNMAGPGAPVTTTEPVTVQE--------ILQRPR 972
T+H+ + + P TG + A N AG V T +TVQE + +PR
Sbjct: 675 GTQHSLCIQEVFPEDTGT---YTCEAWNSAG---EVRTQAVLTVQEPHDGTQPWFISKPR 728
Query: 973 LQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPL---AGEEVSIRNSPTDTI 1029
++ +G+ V + G P P V W ++G+ L G ++N T
Sbjct: 729 ---------SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFT- 778
Query: 1030 LFIRAARRVHSGTYQVTV--RIENMEDKATLVLQ 1061
L ++ + H+G Y++ + R+ + +L+LQ
Sbjct: 779 LVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
Score = 37.0 bits (84), Expect = 0.12
Identities = 38/161 (23%), Positives = 67/161 (41%), Gaps = 12/161 (7%)
Query: 392 AEVKWLKNGQEIQMSG---SKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCSTELF 448
A KW K G ++ G S + + +++ T S S + + + E
Sbjct: 1690 ARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAV 1749
Query: 449 VKEPPVL---ITRPLEDQLVMVGQRVEFECEVSE-EGAQVKWLKDGVELTREETFKYRFK 504
+E P + ++ + D V+ G F+C++ +V W KD + F+ +
Sbjct: 1750 AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD 1809
Query: 505 KDGQRHHLIINEAMLEDAGHYA--LCTSGGQA--LAELIVQ 541
+DG LII++ +D Y S G+A AELIV+
Sbjct: 1810 EDG-NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
Score = 35.4 bits (80), Expect = 0.35
Identities = 31/127 (24%), Positives = 46/127 (36%), Gaps = 32/127 (25%)
Query: 645 PKIHLDCPGRIPDT---IVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDA 701
P I +CP + +VV G R I+G P P V W K GN P +P+
Sbjct: 153 PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLK----GN-VPLQPS--- 204
Query: 702 PEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQ 761
RV V + + G ++D GVYT V N G+
Sbjct: 205 ---------------------ARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKAS 243
Query: 762 VNLTVKV 768
++ + +
Sbjct: 244 MSAELSI 250
Score = 32.0 bits (71), Expect = 3.9
Identities = 25/82 (30%), Positives = 36/82 (43%), Gaps = 5/82 (6%)
Query: 374 QVSKGHKIRLTVELADH-DAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDA 432
+V +G R ++ + D EV W K+ Q I+ S I +L IS DDA
Sbjct: 1768 EVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDA 1827
Query: 433 AYQC----VVGGEKCSTELFVK 450
Y C +G C+ EL V+
Sbjct: 1828 KYTCKAVNSLGEATCTAELIVE 1849
Score = 31.2 bits (69), Expect = 6.6
Identities = 29/106 (27%), Positives = 41/106 (38%), Gaps = 8/106 (7%)
Query: 954 APVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQP 1013
AP T P E + +L R + K G+ G+P+PQVTW K P
Sbjct: 146 APAVETRPSIWGECPPKFATKLGR-----VVVKEGQMGRFSCKITGRPQPQVTWLKGNVP 200
Query: 1014 L-AGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATL 1058
L VS+ +L I + G Y T + N KA++
Sbjct: 201 LQPSARVSVSEKNGMQVLEIHGVNQDDVGVY--TCLVVNGSGKASM 244
>gi|116008192 myosin light chain kinase isoform 1 [Homo sapiens]
Length = 1914
Score = 107 bits (266), Expect = 9e-23
Identities = 200/919 (21%), Positives = 325/919 (35%), Gaps = 153/919 (16%)
Query: 4 PGKKPVSAFSKKPRSVEVAAGSPAVFEAETE-RAGVKVRWQRGGSDISASNKYGLATEGT 62
P K F + ++V GS + +V W G++I S + GT
Sbjct: 617 PSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGT 676
Query: 63 RHTLTVREVGPADQGSYAVIAGSSKVKFDLKVIEAEKAEPMLAPAPAPAEATGAPGEAPA 122
+H+L ++EV P D G+Y EA + GE
Sbjct: 677 QHSLCIQEVFPEDTGTYT------------------------------CEAWNSAGEV-- 704
Query: 123 PAAELGESAPSPKGSSSAALNGPTPGAPDDPIGLFVMRPQDGEVTVGGSITFSARVAGAS 182
+ A L P P F+ +P+ ++G S+ S +AG
Sbjct: 705 --------------RTQAVLTVQEPHDGTQP--WFISKPRSVTASLGQSVLISCAIAGDP 748
Query: 183 LLKPPVVKWFK-GKWVDLSSKVGQHLQLHDSYDRASKVYLFELHITDAQPAFTGSYRCEV 241
P V W + GK + + + LQ D +F L + QP G Y E+
Sbjct: 749 F---PTVHWLRDGKALCKDTGHFEVLQNED---------VFTLVLKKVQPWHAGQY--EI 794
Query: 242 STKDKF-DCSNFNLTVHEAMGTGDLDLLSAFRRTS----LAGGGRRISDSHEDTGILDFS 296
K++ +CS V + L R + L GGG D +
Sbjct: 795 LLKNRVGECS---CQVSLMLQNSSARALPRGREPASCEDLCGGGVGADGGGSDR----YG 847
Query: 297 SLLKKRDSFRTPRDSKLEAPAEEDVWEILRQAPPS-----------EYERIAFQYGVTDL 345
SL R + LE EDV +L++ + E E++ F+ DL
Sbjct: 848 SL---RPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFR----DL 900
Query: 346 RGMLKRLKGMRRDEKKSTAFQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQM 405
G K + D+ K PA Q+ ++ V+ E + + + Q++
Sbjct: 901 LGKKVSTKTLSEDDLKEI-------PAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDF 953
Query: 406 SGSKYIFESIGAKRTLTISQCSLADDAA--YQCVVGGEK-CSTELFVKEPPVLITRPLED 462
+ + G +T + A ++ V+GG+K E L + +E
Sbjct: 954 ---RSVLAKKGTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVES 1010
Query: 463 QLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFK-KDGQRHHLIINEAMLED 521
+ + + + LK ET K K + E + +D
Sbjct: 1011 SKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKD 1070
Query: 522 AGHYALCTSGGQALAELIVQEKKLEVY-------QSIADLMVGAKDQAVFKCEVS-DENV 573
+ C G + EK+ E Q + D+ V + + +C+VS D
Sbjct: 1071 VKNDVNCKRGHAGTTD---NEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPA 1127
Query: 574 RGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFME 633
+W NGK L I +S G + ++I+ P D Y V + A +
Sbjct: 1128 TIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSC---Q 1184
Query: 634 VKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKA 693
V +D P E K R ++ V G + D + PAP T A
Sbjct: 1185 VTVDDAPASENTKAPEMKSRRPKSSLPPVLGTES--DATVKKKPAPK-------TPPKAA 1235
Query: 694 PARPAPDAPED----TGDSDE--------------WVFDKKLLCETEGRVRVETTKDRSI 735
PED G+S E W+ +K + E+E ++VE +++ S
Sbjct: 1236 MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESE-HMKVENSENGSK 1294
Query: 736 FTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPA-APKISNVGEDSCTVQWEP 794
T+ A +E G YT+ V+N +G Q + + V+D PD PA P S++ S T+ W
Sbjct: 1295 LTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYG 1354
Query: 795 PAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGM 854
+YDGG + Y +E + W L + S + ++ Y+ RV A+N G
Sbjct: 1355 SSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYKFRVRAINVYGT 1412
Query: 855 SRPSPASQPFMPIGPPSEP 873
S PS S+ P EP
Sbjct: 1413 SEPSQESELTTVGEKPEEP 1431
Score = 65.9 bits (159), Expect = 2e-10
Identities = 93/402 (23%), Positives = 139/402 (34%), Gaps = 78/402 (19%)
Query: 393 EVKWLKNGQEIQ-MSGSKYIFESIGAKRTLTISQCSLADDAAYQCVV----GGEKCSTEL 447
EV W G ++ GS ++E G+ L + + D Y C G CS L
Sbjct: 444 EVAWFLEGTPVRRQEGSIEVYEDAGS-HYLCLLKARTRDSGTYSCTASNAQGQLSCSWTL 502
Query: 448 FVKEPPVLITRP-----LEDQLVMVGQRVEFECEVSEEGA-QVKWLKDGVELTREETFKY 501
V+ V+ P L+D V+ GQ +C V ++ WL +G + +Y
Sbjct: 503 QVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNG------QPIQY 556
Query: 502 -RFKKDGQRHHLIINEAMLEDAGHYALCTSGG----QALAELIVQEKKLE---------- 546
R + L I +A+ ED G Y A + V EKK
Sbjct: 557 ARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVA 616
Query: 547 --------VYQSIADLMVGAKDQAVFKCEVS-DENVRGVWLKNGKELVPDSRIKVSHIGR 597
Q ++DL V Q +VS + +WL NG E+ G
Sbjct: 617 PSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGT 676
Query: 598 VHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPD 657
H L I +V P D Y+ A N + ++ V + QEP P
Sbjct: 677 QHSLCIQEVFPEDTGTYTCE----AWNSAGEVRTQAV----LTVQEPHDGTQPWFISKPR 728
Query: 658 TIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKL 717
++ G + + I+GDP PTV W+ D K
Sbjct: 729 SVTASLGQSVLISCAIAGDPFPTV----------------------------HWLRDGKA 760
Query: 718 LCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGE 759
LC+ G V +D ++ + G Y + +KN VGE
Sbjct: 761 LCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE 802
Score = 62.0 bits (149), Expect = 3e-09
Identities = 80/327 (24%), Positives = 133/327 (40%), Gaps = 54/327 (16%)
Query: 461 EDQLVMVGQRVEFECEVSE-EGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAML 519
+ Q V Q V+F CEVS +V W +G + R+E +D H+L + +A
Sbjct: 421 QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEG-SIEVYEDAGSHYLCLLKART 479
Query: 520 EDAGHYALCTSG---GQALAELIVQEKKLEVYQSIADLMVGAKDQA-------VFKCEVS 569
D+G Y+ CT+ GQ +Q ++L V + KD A V +C V
Sbjct: 480 RDSGTYS-CTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVR 538
Query: 570 DENV-RGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEG----FACN 624
V R WL NG+ P + + V +L I D P D Y+ + E +C+
Sbjct: 539 GTPVPRITWLLNGQ---PIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCS 595
Query: 625 LSAKLHFMEV--KIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVI 682
+H + K +++ P K + + V+ G+++ + V +SG+P P VI
Sbjct: 596 AWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVI 655
Query: 683 WQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAE 742
W + GN + +S+++ F+++ + ++
Sbjct: 656 W---LHNGN------------EIQESEDFHFEQR--------------GTQHSLCIQEVF 686
Query: 743 KEDEGVYTVTVKNPVGE--DQVNLTVK 767
ED G YT N GE Q LTV+
Sbjct: 687 PEDTGTYTCEAWNSAGEVRTQAVLTVQ 713
Score = 61.6 bits (148), Expect = 5e-09
Identities = 73/311 (23%), Positives = 119/311 (38%), Gaps = 34/311 (10%)
Query: 981 QTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIR--NSPTDTILFIRAARRV 1038
Q+ + K + V G P+P+V W EG P+ +E SI L + AR
Sbjct: 421 QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTR 480
Query: 1039 HSGTYQVTVRIENMEDKATLVLQV----VDKPSPP-----QDLRVTDA--WGLNVALEWK 1087
SGTY T + + LQV V + +P +D V + + L ++
Sbjct: 481 DSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGT 540
Query: 1088 PPQDV-----GNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQ 1142
P + G + + +A + L T+ + E +G +V
Sbjct: 541 PVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALG-----QVSCS 595
Query: 1143 NMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCC 1202
V ++ ++ K +P + P AP F Q L + V+ G +
Sbjct: 596 AWVTVHEKKSSRKSEYLLP---VAPSKPT--------APIFLQGLSDLKVMDGSQVTMTV 644
Query: 1203 AVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEA 1262
V G+P P++ W NG ++ E F + +L I++ P D G Y C A N GE
Sbjct: 645 QVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEV 704
Query: 1263 RCECRLEVRVP 1273
R + L V+ P
Sbjct: 705 RTQAVLTVQEP 715
Score = 61.6 bits (148), Expect = 5e-09
Identities = 57/198 (28%), Positives = 82/198 (41%), Gaps = 12/198 (6%)
Query: 954 APVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTK-EGQ 1012
AP T + +I+Q P Q R GE V L G TW K Q
Sbjct: 1227 APKTPPKAAMPPQIIQFPEDQKVR---------AGESVELFGKVTGTQPITCTWMKFRKQ 1277
Query: 1013 PLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDL 1072
E + + NS + L I AAR+ H G Y + V + +A + L VVDKP PP
Sbjct: 1278 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGT 1337
Query: 1073 R-VTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELII 1131
+D ++ L W G + + Y+++ D W L R T V +L+
Sbjct: 1338 PCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTW-KELATCRSTSFNVQDLLP 1396
Query: 1132 GNGYYFRVFSQNMVGFSD 1149
+ Y FRV + N+ G S+
Sbjct: 1397 DHEYKFRVRAINVYGTSE 1414
Score = 57.0 bits (136), Expect = 1e-07
Identities = 34/112 (30%), Positives = 53/112 (47%), Gaps = 1/112 (0%)
Query: 1160 IPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGL 1219
I + ++ +P ++ +EAP+F P N + G TA VRG P+P+++W +NG
Sbjct: 12 ISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQ 71
Query: 1220 DLGEDARFRM-FSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
+ RF + +G +L I D G Y C ATN G + L V
Sbjct: 72 PITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
Score = 57.0 bits (136), Expect = 1e-07
Identities = 104/493 (21%), Positives = 172/493 (34%), Gaps = 90/493 (18%)
Query: 85 SSKVKFDLKVIEAEKAEP---MLAPAPAPAEATGAPGEAPAPAAELGESAPSPKGSSSAA 141
SS + ++ E P +L+P+ + P A P + G + S +A
Sbjct: 342 SSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVV-SKAAN 400
Query: 142 LNGPTPGAPDDPIGLFVMRPQDGEVTVGGSITFSARVAGASLLKPPVVKWFKGKWVDLSS 201
P G D F +PQ EV ++ F V+G + P V WF +
Sbjct: 401 RRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSG---IPKPEVAWFLE-----GT 452
Query: 202 KVGQHLQLHDSYDRASKVYLFELHITDAQPAFTGSYRCEVSTKDKFDCSNFNLTVHEAMG 261
V + + Y+ A YL + A+ +G+Y C T A G
Sbjct: 453 PVRRQEGSIEVYEDAGSHYLC---LLKARTRDSGTYSC---------------TASNAQG 494
Query: 262 TGDLDLLSAFRRTSLAGGGRRISDSHEDTGILDFSSLLKKRDSFRTPRDSKLEAPAEEDV 321
R ++ S +D +++ + + S P
Sbjct: 495 QLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL--------QCSVRGTPVPRIT 546
Query: 322 WEILRQAPPSEYERIAFQYGVTDLR--------------------GMLKRLKGMRRDEKK 361
W L P +Y R + GV +L G + + EKK
Sbjct: 547 W--LLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKK 604
Query: 362 STAFQKKLEPA----------------YQVSKGHKIRLTVELADH-DAEVKWLKNGQEIQ 404
S+ + L P +V G ++ +TV+++ + EV WL NG EIQ
Sbjct: 605 SSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQ 664
Query: 405 MSGSKYIFESIGAKRTLTISQCSLADDAAYQC----VVGGEKCSTELFVKEP-----PVL 455
S + FE G + +L I + D Y C G + L V+EP P
Sbjct: 665 ES-EDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWF 723
Query: 456 ITRPLEDQLVMVGQRVEFECEVS-EEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLII 514
I++P +GQ V C ++ + V WL+DG L + +T + ++ L++
Sbjct: 724 ISKP-RSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCK-DTGHFEVLQNEDVFTLVL 781
Query: 515 NEAMLEDAGHYAL 527
+ AG Y +
Sbjct: 782 KKVQPWHAGQYEI 794
Score = 57.0 bits (136), Expect = 1e-07
Identities = 34/92 (36%), Positives = 48/92 (52%), Gaps = 2/92 (2%)
Query: 1180 APSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVL-TL 1238
AP+F Q L + V G +L C V P I W NG L + +F + S++G L ++
Sbjct: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTL-KTTKFIILSQEGSLCSV 1155
Query: 1239 EIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
I K P D G+Y C A N G+A C C++ V
Sbjct: 1156 SIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1187
Score = 56.6 bits (135), Expect = 1e-07
Identities = 29/91 (31%), Positives = 45/91 (49%), Gaps = 1/91 (1%)
Query: 1181 PSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRM-FSKQGVLTLE 1239
P F++ + + V+ G A C + G P P++ WFK+ + E F++ + + G +L
Sbjct: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868
Query: 1240 IRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
I C D Y C+A N GEA C L V
Sbjct: 1869 ISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899
Score = 54.7 bits (130), Expect = 6e-07
Identities = 75/309 (24%), Positives = 123/309 (39%), Gaps = 55/309 (17%)
Query: 988 GEPVNLLIPFQGKPRPQVTWTKEGQPL--------AG-EEVSIRNS-PTD----TILFIR 1033
G+ L +G P P++TW GQP+ AG E+ I+++ P D T L
Sbjct: 528 GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAEN 587
Query: 1034 AARRVHSGTYQVTVRIENMEDKATLVLQVV-DKPSPP------QDLRVTDAWG--LNVAL 1084
A +V + VTV + K+ +L V KP+ P DL+V D + V +
Sbjct: 588 ALGQVSCSAW-VTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQV 646
Query: 1085 EWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNM 1144
PP +V +W + + + E F + + + E+ + + + N
Sbjct: 647 SGNPPPEV----IWLHNGNEIQES--EDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNS 700
Query: 1145 VGF--SDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIA--GYTAML 1200
G + T +EP +P +P RSV A G + ++
Sbjct: 701 AGEVRTQAVLTVQEPHDGTQPWFISKP--------------------RSVTASLGQSVLI 740
Query: 1201 CCAVRGSPKPKISWFKNGLDLGED-ARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQ 1259
CA+ G P P + W ++G L +D F + + V TL ++K P+ G Y N
Sbjct: 741 SCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRV 800
Query: 1260 GEARCECRL 1268
GE C+ L
Sbjct: 801 GECSCQVSL 809
Score = 52.8 bits (125), Expect = 2e-06
Identities = 33/115 (28%), Positives = 45/115 (39%), Gaps = 10/115 (8%)
Query: 1157 PVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFK 1216
P RP I E P P F L V G C + G P+P+++W K
Sbjct: 147 PAVETRPSIWGECP----------PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLK 196
Query: 1217 NGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVR 1271
+ L AR + K G+ LEI D G+Y C N G+A L ++
Sbjct: 197 GNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251
Score = 49.3 bits (116), Expect = 2e-05
Identities = 28/94 (29%), Positives = 42/94 (44%), Gaps = 1/94 (1%)
Query: 1178 SEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDL-GEDARFRMFSKQGVL 1236
S P F ++ V T C V G PKP+++WF G + ++ ++ G
Sbjct: 411 SAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSH 470
Query: 1237 TLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
L + K D G Y C A+N QG+ C L+V
Sbjct: 471 YLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQV 504
Score = 46.2 bits (108), Expect = 2e-04
Identities = 80/367 (21%), Positives = 123/367 (33%), Gaps = 98/367 (26%)
Query: 661 VVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCE 720
V G KL L +S DP T+IW T + K ++
Sbjct: 1109 VAEGKKLLLQCQVSSDPPATIIW---------------------TLNGKTLKTTKFIILS 1147
Query: 721 TEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVP--DAPAAP 778
EG + ++E A ED G+Y KN G+ + + V V D P + AP
Sbjct: 1148 QEGSL--------CSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAP 1199
Query: 779 KISN----------VGEDSCTVQWEPPA-------------------------------- 796
++ + +G +S + PA
Sbjct: 1200 EMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFG 1259
Query: 797 -YDGGQPIL-GYILERKKKKSYRWMRL-NFDLIQELSHEARRMIEGVVYEM--------R 845
G QPI ++ RK+ + M++ N + +L+ A R Y + R
Sbjct: 1260 KVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSR 1319
Query: 846 VYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYS 905
VN + +P P P G P D+ ++++L W G + YS
Sbjct: 1320 QAQVNLTVVDKPDP------PAGTP------CASDIRSSSLTLSWYGSSYDGGSAVQSYS 1367
Query: 906 VEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQ 965
+E W TS V+DL FRVRA N+ G P +E TV
Sbjct: 1368 IEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG 1425
Query: 966 EILQRPR 972
E + P+
Sbjct: 1426 EKPEEPK 1432
Score = 44.3 bits (103), Expect = 8e-04
Identities = 85/394 (21%), Positives = 144/394 (36%), Gaps = 71/394 (18%)
Query: 711 WVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVID 770
W + + EG + V + A D G Y+ T N G+ + T++V
Sbjct: 447 WFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVER 506
Query: 771 VPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELS 830
+ AP S+V +D + +G +L + W+ LN IQ
Sbjct: 507 LAVMEVAPSFSSVLKDCAVI-------EGQDFVLQCSVRGTPVPRITWL-LNGQPIQ--- 555
Query: 831 HEARRMIEGVVYEMRV-------------YAVNAIGM-----------SRPSPASQPFMP 866
AR E V E+ + A NA+G + S S+ +P
Sbjct: 556 -YARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLP 614
Query: 867 IGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGC----SEWVAALQG 922
+ P + ++ +SD V + V G V + G SE Q
Sbjct: 615 VAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQR 674
Query: 923 LTEHTSILVKDLP--TGARLLFRVRAHNMAGPGAPVTTTEPVTVQE--------ILQRPR 972
T+H+ + + P TG + A N AG V T +TVQE + +PR
Sbjct: 675 GTQHSLCIQEVFPEDTGT---YTCEAWNSAG---EVRTQAVLTVQEPHDGTQPWFISKPR 728
Query: 973 LQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPL---AGEEVSIRNSPTDTI 1029
++ +G+ V + G P P V W ++G+ L G ++N T
Sbjct: 729 ---------SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFT- 778
Query: 1030 LFIRAARRVHSGTYQVTV--RIENMEDKATLVLQ 1061
L ++ + H+G Y++ + R+ + +L+LQ
Sbjct: 779 LVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
Score = 37.0 bits (84), Expect = 0.12
Identities = 38/161 (23%), Positives = 67/161 (41%), Gaps = 12/161 (7%)
Query: 392 AEVKWLKNGQEIQMSG---SKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCSTELF 448
A KW K G ++ G S + + +++ T S S + + + E
Sbjct: 1741 ARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAV 1800
Query: 449 VKEPPVL---ITRPLEDQLVMVGQRVEFECEVSE-EGAQVKWLKDGVELTREETFKYRFK 504
+E P + ++ + D V+ G F+C++ +V W KD + F+ +
Sbjct: 1801 AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD 1860
Query: 505 KDGQRHHLIINEAMLEDAGHYA--LCTSGGQA--LAELIVQ 541
+DG LII++ +D Y S G+A AELIV+
Sbjct: 1861 EDG-NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900
Score = 35.4 bits (80), Expect = 0.35
Identities = 31/127 (24%), Positives = 46/127 (36%), Gaps = 32/127 (25%)
Query: 645 PKIHLDCPGRIPDT---IVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDA 701
P I +CP + +VV G R I+G P P V W K GN P +P+
Sbjct: 153 PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLK----GN-VPLQPS--- 204
Query: 702 PEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQ 761
RV V + + G ++D GVYT V N G+
Sbjct: 205 ---------------------ARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKAS 243
Query: 762 VNLTVKV 768
++ + +
Sbjct: 244 MSAELSI 250
Score = 32.0 bits (71), Expect = 3.9
Identities = 25/82 (30%), Positives = 36/82 (43%), Gaps = 5/82 (6%)
Query: 374 QVSKGHKIRLTVELADH-DAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDA 432
+V +G R ++ + D EV W K+ Q I+ S I +L IS DDA
Sbjct: 1819 EVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDA 1878
Query: 433 AYQC----VVGGEKCSTELFVK 450
Y C +G C+ EL V+
Sbjct: 1879 KYTCKAVNSLGEATCTAELIVE 1900
Score = 31.2 bits (69), Expect = 6.6
Identities = 29/106 (27%), Positives = 41/106 (38%), Gaps = 8/106 (7%)
Query: 954 APVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQP 1013
AP T P E + +L R + K G+ G+P+PQVTW K P
Sbjct: 146 APAVETRPSIWGECPPKFATKLGR-----VVVKEGQMGRFSCKITGRPQPQVTWLKGNVP 200
Query: 1014 L-AGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATL 1058
L VS+ +L I + G Y T + N KA++
Sbjct: 201 LQPSARVSVSEKNGMQVLEIHGVNQDDVGVY--TCLVVNGSGKASM 244
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.134 0.403
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 54,863,821
Number of Sequences: 37866
Number of extensions: 2861414
Number of successful extensions: 24464
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 205
Number of HSP's successfully gapped in prelim test: 411
Number of HSP's that attempted gapping in prelim test: 13131
Number of HSP's gapped (non-prelim): 7099
length of query: 1274
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1160
effective length of database: 13,930,794
effective search space: 16159721040
effective search space used: 16159721040
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.