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Search of human proteins with 14670383
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|14670383 death-associated kinase 2 [Homo sapiens]
(370 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|14670383 death-associated kinase 2 [Homo sapiens] 732 0.0
gi|89363047 death-associated protein kinase 1 [Homo sapiens] 503 e-143
gi|4557511 death-associated protein kinase 3 [Homo sapiens] 454 e-128
gi|116008192 myosin light chain kinase isoform 1 [Homo sapiens] 268 6e-72
gi|116008188 myosin light chain kinase isoform 2 [Homo sapiens] 268 6e-72
gi|109255245 serine/threonine kinase 17a [Homo sapiens] 255 5e-68
gi|4758194 serine/threonine kinase 17B [Homo sapiens] 249 2e-66
gi|167466233 myosin light chain kinase family, member 4 [Homo sa... 249 4e-66
gi|146219832 myosin light chain kinase 3 [Homo sapiens] 247 1e-65
gi|14993776 skeletal myosin light chain kinase [Homo sapiens] 234 9e-62
gi|148839466 kalirin, RhoGEF kinase isoform 1 [Homo sapiens] 228 5e-60
gi|68362740 kalirin, RhoGEF kinase isoform 3 [Homo sapiens] 228 5e-60
gi|9966875 calcium/calmodulin-dependent protein kinase ID isofor... 219 2e-57
gi|23943850 calcium/calmodulin-dependent protein kinase ID isofo... 219 2e-57
gi|209364621 pregnancy upregulated non-ubiquitously expressed Ca... 212 4e-55
gi|209364619 pregnancy upregulated non-ubiquitously expressed Ca... 212 4e-55
gi|110349719 titin isoform N2-A [Homo sapiens] 211 1e-54
gi|110349717 titin isoform novex-2 [Homo sapiens] 211 1e-54
gi|110349713 titin isoform novex-1 [Homo sapiens] 211 1e-54
gi|110349715 titin isoform N2-B [Homo sapiens] 211 1e-54
gi|26667183 calcium/calmodulin-dependent protein kinase II delta... 208 5e-54
gi|26667186 calcium/calmodulin-dependent protein kinase II delta... 208 5e-54
gi|26667189 calcium/calmodulin-dependent protein kinase II delta... 208 5e-54
gi|26667180 calcium/calmodulin-dependent protein kinase II delta... 208 5e-54
gi|14196445 calcium/calmodulin-dependent protein kinase IG [Homo... 208 5e-54
gi|212549753 calcium/calmodulin-dependent protein kinase II delt... 207 2e-53
gi|4502557 calcium/calmodulin-dependent protein kinase IV [Homo ... 206 4e-53
gi|212549756 calcium/calmodulin-dependent protein kinase II delt... 205 6e-53
gi|4502553 calcium/calmodulin-dependent protein kinase I [Homo s... 205 6e-53
gi|157785645 SPEG complex locus [Homo sapiens] 203 2e-52
>gi|14670383 death-associated kinase 2 [Homo sapiens]
Length = 370
Score = 732 bits (1890), Expect = 0.0
Identities = 370/370 (100%), Positives = 370/370 (100%)
Query: 1 MFQASMRSPNMEPFKQQKVEDFYDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSR 60
MFQASMRSPNMEPFKQQKVEDFYDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSR
Sbjct: 1 MFQASMRSPNMEPFKQQKVEDFYDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSR 60
Query: 61 ASRRGVSREEIEREVSILRQVLHHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKES 120
ASRRGVSREEIEREVSILRQVLHHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKES
Sbjct: 61 ASRRGVSREEIEREVSILRQVLHHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKES 120
Query: 121 LSEEEATSFIKQILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIED 180
LSEEEATSFIKQILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIED
Sbjct: 121 LSEEEATSFIKQILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIED 180
Query: 181 GVEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANIT 240
GVEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANIT
Sbjct: 181 GVEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANIT 240
Query: 241 AVSYDFDEEFFSQTSELAKDFIRKLLVKETRKRLTIQEALRHPWITPVDNQQAMVRRESV 300
AVSYDFDEEFFSQTSELAKDFIRKLLVKETRKRLTIQEALRHPWITPVDNQQAMVRRESV
Sbjct: 241 AVSYDFDEEFFSQTSELAKDFIRKLLVKETRKRLTIQEALRHPWITPVDNQQAMVRRESV 300
Query: 301 VNLENFRKQYVRRRWKLSFSIVSLCNHLTRSLMKKVHLRPDEDLRNCESDTEEDIARRKA 360
VNLENFRKQYVRRRWKLSFSIVSLCNHLTRSLMKKVHLRPDEDLRNCESDTEEDIARRKA
Sbjct: 301 VNLENFRKQYVRRRWKLSFSIVSLCNHLTRSLMKKVHLRPDEDLRNCESDTEEDIARRKA 360
Query: 361 LHPRRRSSTS 370
LHPRRRSSTS
Sbjct: 361 LHPRRRSSTS 370
>gi|89363047 death-associated protein kinase 1 [Homo sapiens]
Length = 1430
Score = 503 bits (1296), Expect = e-143
Identities = 244/355 (68%), Positives = 304/355 (85%), Gaps = 8/355 (2%)
Query: 11 MEPFKQQKVEDFYDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVSREE 70
M F+Q+ V+D+YD GEELGSGQFA+VKKCREKSTGL+YAAKFIKKR++++SRRGVSRE+
Sbjct: 1 MTVFRQENVDDYYDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGVSRED 60
Query: 71 IEREVSILRQVLHHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSFI 130
IEREVSIL+++ H NVITLH+VYEN+TDV+LILELV+GGELFDFLA+KESL+EEEAT F+
Sbjct: 61 IEREVSILKEIQHPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFL 120
Query: 131 KQILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNIFGT 190
KQIL+GV YLH+ +IAHFDLKPENIMLLD+N+P P IK+IDFGLAH+I+ G EFKNIFGT
Sbjct: 121 KQILNGVYYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGNEFKNIFGT 180
Query: 191 PEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANITAVSYDFDEEF 250
PEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLAN++AV+Y+F++E+
Sbjct: 181 PEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANVSAVNYEFEDEY 240
Query: 251 FSQTSELAKDFIRKLLVKETRKRLTIQEALRHPWITPVDNQQAMVRRESVVNLENFRKQY 310
FS TS LAKDFIR+LLVK+ +KR+TIQ++L+HPWI P D QQA+ R+ S VN+E F+K
Sbjct: 241 FSNTSALAKDFIRRLLVKDPKKRMTIQDSLQHPWIKPKDTQQALSRKASAVNMEKFKKFA 300
Query: 311 VRRRWKLSFSIVSLCNHLTRSLMKKVHL---RPDEDLRNCESDTEEDIARRKALH 362
R++WK S ++SLC L+RS + + ++ R D+ L D E+ + +H
Sbjct: 301 ARKKWKQSVRLISLCQRLSRSFLSRSNMSVARSDDTL-----DEEDSFVMKAIIH 350
>gi|4557511 death-associated protein kinase 3 [Homo sapiens]
Length = 454
Score = 454 bits (1168), Expect = e-128
Identities = 225/303 (74%), Positives = 265/303 (87%), Gaps = 7/303 (2%)
Query: 11 MEPFKQQKVEDFYDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVSREE 70
M F+Q+ VED Y++GEELGSGQFAIV+KCR+K TG EYAAKFIKKR+ +SRRGVSREE
Sbjct: 1 MSTFRQEDVEDHYEMGEELGSGQFAIVRKCRQKGTGKEYAAKFIKKRRLSSSRRGVSREE 60
Query: 71 IEREVSILRQVLHHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSFI 130
IEREV+ILR++ H N+ITLHD++EN+TDVVLILELVSGGELFDFLA+KESL+E+EAT F+
Sbjct: 61 IEREVNILREIRHPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFL 120
Query: 131 KQILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNIFGT 190
KQILDGV+YLH+K+IAHFDLKPENIMLLDKN+P P IKLIDFG+AH+IE G EFKNIFGT
Sbjct: 121 KQILDGVHYLHSKRIAHFDLKPENIMLLDKNVPNPRIKLIDFGIAHKIEAGNEFKNIFGT 180
Query: 191 PEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANITAVSYDFDEEF 250
PEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLG+TKQETL NI+AV+YDFDEE+
Sbjct: 181 PEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGETKQETLTNISAVNYDFDEEY 240
Query: 251 FSQTSELAKDFIRKLLVKETRKRLTIQEALRHPWITPVDNQQAMVRRESVVNLENFRKQY 310
FS TSELAKDFIR+LLVK+ ++R+TI ++L H WI +RR +V ++ RK
Sbjct: 241 FSNTSELAKDFIRRLLVKDPKRRMTIAQSLEHSWI-------KAIRRRNVRGEDSGRKPE 293
Query: 311 VRR 313
RR
Sbjct: 294 RRR 296
>gi|116008192 myosin light chain kinase isoform 1 [Homo sapiens]
Length = 1914
Score = 268 bits (685), Expect = 6e-72
Identities = 144/350 (41%), Positives = 215/350 (61%), Gaps = 20/350 (5%)
Query: 16 QQKVEDFYDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVSREEIEREV 75
+QKV DFYDI E LGSG+F V + EK T +A KF K ++ +E I +E+
Sbjct: 1457 EQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAK------EKENIRQEI 1510
Query: 76 SILRQVLHHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKE-SLSEEEATSFIKQIL 134
SI+ + H ++ D +E + ++V++LE+VSGGELF+ + ++ L+E E +++QI
Sbjct: 1511 SIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQIS 1570
Query: 135 DGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNIFGTPEFV 194
+GV Y+H + I H DLKPENIM ++K IKLIDFGLA +E+ K +FGTPEFV
Sbjct: 1571 EGVEYIHKQGIVHLDLKPENIMCVNKTGT--RIKLIDFGLARRLENAGSLKVLFGTPEFV 1628
Query: 195 APEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANITAVSYDFDEEFFSQT 254
APE++NYEP+G DMWSIGVI YIL+SG SPF+GD ETLAN+T+ ++DFD+E F +
Sbjct: 1629 APEVINYEPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDFDDEAFDEI 1688
Query: 255 SELAKDFIRKLLVKETRKRLTIQEALRHPWITPVDNQQAMVRRESVVNLENFRKQYVRRR 314
S+ AKDFI LL K+ + RL + L+HPW+ D + ++ ++ + +K RR+
Sbjct: 1689 SDDAKDFISNLLKKDMKNRLDCTQCLQHPWLMK-DTKNMEAKK---LSKDRMKKYMARRK 1744
Query: 315 WKLSFSIVSLCNHLTRSLM-------KKVHLRPDEDLRNCESDTEEDIAR 357
W+ + + V L+ M K P L + ++EED+++
Sbjct: 1745 WQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQ 1794
>gi|116008188 myosin light chain kinase isoform 2 [Homo sapiens]
Length = 1845
Score = 268 bits (685), Expect = 6e-72
Identities = 144/350 (41%), Positives = 215/350 (61%), Gaps = 20/350 (5%)
Query: 16 QQKVEDFYDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVSREEIEREV 75
+QKV DFYDI E LGSG+F V + EK T +A KF K ++ +E I +E+
Sbjct: 1388 EQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAK------EKENIRQEI 1441
Query: 76 SILRQVLHHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKE-SLSEEEATSFIKQIL 134
SI+ + H ++ D +E + ++V++LE+VSGGELF+ + ++ L+E E +++QI
Sbjct: 1442 SIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQIS 1501
Query: 135 DGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNIFGTPEFV 194
+GV Y+H + I H DLKPENIM ++K IKLIDFGLA +E+ K +FGTPEFV
Sbjct: 1502 EGVEYIHKQGIVHLDLKPENIMCVNKTGT--RIKLIDFGLARRLENAGSLKVLFGTPEFV 1559
Query: 195 APEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANITAVSYDFDEEFFSQT 254
APE++NYEP+G DMWSIGVI YIL+SG SPF+GD ETLAN+T+ ++DFD+E F +
Sbjct: 1560 APEVINYEPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDFDDEAFDEI 1619
Query: 255 SELAKDFIRKLLVKETRKRLTIQEALRHPWITPVDNQQAMVRRESVVNLENFRKQYVRRR 314
S+ AKDFI LL K+ + RL + L+HPW+ D + ++ ++ + +K RR+
Sbjct: 1620 SDDAKDFISNLLKKDMKNRLDCTQCLQHPWLMK-DTKNMEAKK---LSKDRMKKYMARRK 1675
Query: 315 WKLSFSIVSLCNHLTRSLM-------KKVHLRPDEDLRNCESDTEEDIAR 357
W+ + + V L+ M K P L + ++EED+++
Sbjct: 1676 WQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQ 1725
>gi|109255245 serine/threonine kinase 17a [Homo sapiens]
Length = 414
Score = 255 bits (651), Expect = 5e-68
Identities = 132/300 (44%), Positives = 200/300 (66%), Gaps = 17/300 (5%)
Query: 12 EPFKQQKVEDFYDI--GEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVS-R 68
EPF +D Y + G ELG G+FA+V+KC +K +G E+AAKF++KR R+G R
Sbjct: 53 EPF-----QDGYSLCPGRELGRGKFAVVRKCIKKDSGKEFAAKFMRKR-----RKGQDCR 102
Query: 69 EEIEREVSILRQVLHHN-VITLHDVYENRTDVVLILELVSGGELFDFLA--QKESLSEEE 125
EI E+++L + VI LH+VYE ++++L+LE +GGE+FD ++E+ E++
Sbjct: 103 MEIIHEIAVLELAQDNPWVINLHEVYETASEMILVLEYAAGGEIFDQCVADREEAFKEKD 162
Query: 126 ATSFIKQILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFK 185
++QIL+GV++LHT+ + H DLKP+NI+L ++ P+ IK++DFGL+ +++ E +
Sbjct: 163 VQRLMRQILEGVHFLHTRDVVHLDLKPQNILLTSES-PLGDIKIVDFGLSRILKNSEELR 221
Query: 186 NIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANITAVSYD 245
I GTPE+VAPEI++Y+P+ + DMWSIGV+TY++L+G SPFLG+ KQET NI+ ++
Sbjct: 222 EIMGTPEYVAPEILSYDPISMATDMWSIGVLTYVMLTGISPFLGNDKQETFLNISQMNLS 281
Query: 246 FDEEFFSQTSELAKDFIRKLLVKETRKRLTIQEALRHPWITPVDNQQAMVRRESVVNLEN 305
+ EE F SE A DFIR LLVK+ R T +E L+HPW+T Q+ R E + N
Sbjct: 282 YSEEEFDVLSESAVDFIRTLLVKKPEDRATAEECLKHPWLTQSSIQEPSFRMEKALEEAN 341
>gi|4758194 serine/threonine kinase 17B [Homo sapiens]
Length = 372
Score = 249 bits (637), Expect = 2e-66
Identities = 133/282 (47%), Positives = 182/282 (64%), Gaps = 11/282 (3%)
Query: 13 PFKQQKVEDFYDI-GEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVS-REE 70
P K + +FY + +ELG G+FA+V++C KSTG EYAAKF+KKR RRG R E
Sbjct: 22 PIKMENFNNFYILTSKELGRGKFAVVRQCISKSTGQEYAAKFLKKR-----RRGQDCRAE 76
Query: 71 IEREVSILRQVLH-HNVITLHDVYENRTDVVLILELVSGGELFDFLAQK--ESLSEEEAT 127
I E+++L VI LH+VYEN ++++LILE +GGE+F + E +SE +
Sbjct: 77 ILHEIAVLELAKSCPRVINLHEVYENTSEIILILEYAAGGEIFSLCLPELAEMVSENDVI 136
Query: 128 SFIKQILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNI 187
IKQIL+GV YLH I H DLKP+NI LL P+ IK++DFG++ +I E + I
Sbjct: 137 RLIKQILEGVYYLHQNNIVHLDLKPQNI-LLSSIYPLGDIKIVDFGMSRKIGHACELREI 195
Query: 188 FGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANITAVSYDFD 247
GTPE++APEI+NY+P+ DMW+IG+I Y+LL+ SPF+G+ QET NI+ V+ D+
Sbjct: 196 MGTPEYLAPEILNYDPITTATDMWNIGIIAYMLLTHTSPFVGEDNQETYLNISQVNVDYS 255
Query: 248 EEFFSQTSELAKDFIRKLLVKETRKRLTIQEALRHPWITPVD 289
EE FS S+LA DFI+ LLVK KR T + L H W+ D
Sbjct: 256 EETFSSVSQLATDFIQSLLVKNPEKRPTAEICLSHSWLQQWD 297
>gi|167466233 myosin light chain kinase family, member 4 [Homo
sapiens]
Length = 388
Score = 249 bits (635), Expect = 4e-66
Identities = 128/275 (46%), Positives = 182/275 (66%), Gaps = 11/275 (4%)
Query: 15 KQQKVEDFYDIG--EELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVSREEIE 72
KQ V FY + E LG G+F V KC E +TGL+ AAK IK R + +EE++
Sbjct: 96 KQGAVNSFYTVSKTEILGGGRFGQVHKCEETATGLKLAAKIIKTRGMK------DKEEVK 149
Query: 73 REVSILRQVLHHNVITLHDVYENRTDVVLILELVSGGELFD-FLAQKESLSEEEATSFIK 131
E+S++ Q+ H N+I L+D +E++ D+VL++E V GGELFD + + +L+E + F+K
Sbjct: 150 NEISVMNQLDHANLIQLYDAFESKNDIVLVMEYVDGGELFDRIIDESYNLTELDTILFMK 209
Query: 132 QILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNIFGTP 191
QI +G+ ++H I H DLKPENI+ ++++ IK+IDFGLA + + K FGTP
Sbjct: 210 QICEGIRHMHQMYILHLDLKPENILCVNRDAK--QIKIIDFGLARRYKPREKLKVNFGTP 267
Query: 192 EFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANITAVSYDFDEEFF 251
EF+APE+VNY+ + DMWS+GVI Y+LLSG SPFLGD ETL NI A +D ++E F
Sbjct: 268 EFLAPEVVNYDFVSFPTDMWSVGVIAYMLLSGLSPFLGDNDAETLNNILACRWDLEDEEF 327
Query: 252 SQTSELAKDFIRKLLVKETRKRLTIQEALRHPWIT 286
SE AK+FI KLL+KE R++ EAL+HPW++
Sbjct: 328 QDISEEAKEFISKLLIKEKSWRISASEALKHPWLS 362
>gi|146219832 myosin light chain kinase 3 [Homo sapiens]
Length = 819
Score = 247 bits (630), Expect = 1e-65
Identities = 136/321 (42%), Positives = 199/321 (61%), Gaps = 16/321 (4%)
Query: 15 KQQKVEDFYDI--GEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVSREEIE 72
K+ + Y++ E LG G+F V +C EKSTGL AAK IK + ++ RE+++
Sbjct: 505 KETSISAGYEVCQHEVLGGGRFGQVHRCTEKSTGLPLAAKIIKVKSAK------DREDVK 558
Query: 73 REVSILRQVLHHNVITLHDVYENRTDVVLILELVSGGELFDFLA-QKESLSEEEATSFIK 131
E++I+ Q+ H N+I L+D +E++ L++E V GGELFD + +K L+E + F +
Sbjct: 559 NEINIMNQLSHVNLIQLYDAFESKHSCTLVMEYVDGGELFDRITDEKYHLTELDVVLFTR 618
Query: 132 QILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNIFGTP 191
QI +GV+YLH I H DLKPENI+ +++ IK+IDFGLA + + K FGTP
Sbjct: 619 QICEGVHYLHQHYILHLDLKPENILCVNQTGH--QIKIIDFGLARRYKPREKLKVNFGTP 676
Query: 192 EFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANITAVSYDFDEEFF 251
EF+APE+VNYE + DMWS+GVITY+LLSG SPFLG+T ET+ I S+DFD + F
Sbjct: 677 EFLAPEVVNYEFVSFPTDMWSVGVITYMLLSGLSPFLGETDAETMNFIVNCSWDFDADTF 736
Query: 252 SQTSELAKDFIRKLLVKETRKRLTIQEALRHPWIT--PVDNQQAMVRRESVVNLENFRKQ 309
SE AKDF+ +LLVKE R++ + L+H W+ P ++ R +S + L+ K
Sbjct: 737 EGLSEEAKDFVSRLLVKEKSCRMSATQCLKHEWLNNLPAKASRSKTRLKSQLLLQ---KY 793
Query: 310 YVRRRWKLSFSIVSLCNHLTR 330
+R+WK F +V+ N L +
Sbjct: 794 IAQRKWKKHFYVVTAANRLRK 814
>gi|14993776 skeletal myosin light chain kinase [Homo sapiens]
Length = 596
Score = 234 bits (597), Expect = 9e-62
Identities = 121/305 (39%), Positives = 185/305 (60%), Gaps = 10/305 (3%)
Query: 27 EELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVSREEIEREVSILRQVLHHNV 86
E LG G+F V C EK+TGL+ AAK IKK+ + +E + E+ ++ Q+ H N+
Sbjct: 289 EALGGGKFGAVCTCMEKATGLKLAAKVIKKQTPK------DKEMVLLEIEVMNQLNHRNL 342
Query: 87 ITLHDVYENRTDVVLILELVSGGELFDFLAQKE-SLSEEEATSFIKQILDGVNYLHTKKI 145
I L+ E ++VL +E + GGELF+ + ++ L+E + F++QI DG+ ++H ++
Sbjct: 343 IQLYAAIETPHEIVLFMEYIEGGELFERIVDEDYHLTEVDTMVFVRQICDGILFMHKMRV 402
Query: 146 AHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNIFGTPEFVAPEIVNYEPLG 205
H DLKPENI+ ++ + +K+IDFGLA + K FGTPEF++PE+VNY+ +
Sbjct: 403 LHLDLKPENILCVNTTGHL--VKIIDFGLARRYNPNEKLKVNFGTPEFLSPEVVNYDQIS 460
Query: 206 LEADMWSIGVITYILLSGASPFLGDTKQETLANITAVSYDFDEEFFSQTSELAKDFIRKL 265
+ DMWS+GVITY+LLSG SPFLGD ETL N+ + ++ FDEE F S+ AKDF+ L
Sbjct: 461 DKTDMWSMGVITYMLLSGLSPFLGDDDTETLNNVLSGNWYFDEETFEAVSDEAKDFVSNL 520
Query: 266 LVKETRKRLTIQEALRHPWITPVDNQQAMVRRESVVNLENFRKQYVRRRWKLSFSIVSLC 325
+VK+ R R+ + L HPW+ + + R + +K ++RRWK +F VS
Sbjct: 521 IVKDQRARMNAAQCLAHPWLNNLAEKAKRCNRRLKSQI-LLKKYLMKRRWKKNFIAVSAA 579
Query: 326 NHLTR 330
N +
Sbjct: 580 NRFKK 584
>gi|148839466 kalirin, RhoGEF kinase isoform 1 [Homo sapiens]
Length = 2986
Score = 228 bits (582), Expect = 5e-60
Identities = 109/272 (40%), Positives = 167/272 (61%), Gaps = 8/272 (2%)
Query: 16 QQKVEDFYDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVSREEIEREV 75
++ + Y E+G G+F+IVKKC K+T + A KF+ K+ + +E+ E
Sbjct: 2677 KENFDSAYTELNEIGRGRFSIVKKCIHKATRKDVAVKFVSKKMKK-------KEQAAHEA 2729
Query: 76 SILRQVLHHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSFIKQILD 135
++L+ + H ITLHD YE+ T +LILEL+ G L D+L + L EE+ +I+ I++
Sbjct: 2730 ALLQHLQHPQYITLHDTYESPTSYILILELMDDGRLLDYLMNHDELMEEKVAFYIRDIME 2789
Query: 136 GVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNIFGTPEFVA 195
+ YLH ++AH D+KPEN+ L+D IP+P +KLID A +I ++ G PEF A
Sbjct: 2790 ALQYLHNCRVAHLDIKPENL-LIDLRIPVPRVKLIDLEDAVQISGHFHIHHLLGNPEFAA 2848
Query: 196 PEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANITAVSYDFDEEFFSQTS 255
PE++ P+ L D+WSIGV+TY++LSG SPFL ++K+ET N+ V + F E+F S
Sbjct: 2849 PEVIQGIPVSLGTDIWSIGVLTYVMLSGVSPFLDESKEETCINVCRVDFSFPHEYFCGVS 2908
Query: 256 ELAKDFIRKLLVKETRKRLTIQEALRHPWITP 287
A+DFI +L ++ R+R T L+HPW+ P
Sbjct: 2909 NAARDFINVILQEDFRRRPTAATCLQHPWLQP 2940
>gi|68362740 kalirin, RhoGEF kinase isoform 3 [Homo sapiens]
Length = 1289
Score = 228 bits (582), Expect = 5e-60
Identities = 109/272 (40%), Positives = 167/272 (61%), Gaps = 8/272 (2%)
Query: 16 QQKVEDFYDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVSREEIEREV 75
++ + Y E+G G+F+IVKKC K+T + A KF+ K+ + +E+ E
Sbjct: 980 KENFDSAYTELNEIGRGRFSIVKKCIHKATRKDVAVKFVSKKMKK-------KEQAAHEA 1032
Query: 76 SILRQVLHHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSFIKQILD 135
++L+ + H ITLHD YE+ T +LILEL+ G L D+L + L EE+ +I+ I++
Sbjct: 1033 ALLQHLQHPQYITLHDTYESPTSYILILELMDDGRLLDYLMNHDELMEEKVAFYIRDIME 1092
Query: 136 GVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNIFGTPEFVA 195
+ YLH ++AH D+KPEN+ L+D IP+P +KLID A +I ++ G PEF A
Sbjct: 1093 ALQYLHNCRVAHLDIKPENL-LIDLRIPVPRVKLIDLEDAVQISGHFHIHHLLGNPEFAA 1151
Query: 196 PEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANITAVSYDFDEEFFSQTS 255
PE++ P+ L D+WSIGV+TY++LSG SPFL ++K+ET N+ V + F E+F S
Sbjct: 1152 PEVIQGIPVSLGTDIWSIGVLTYVMLSGVSPFLDESKEETCINVCRVDFSFPHEYFCGVS 1211
Query: 256 ELAKDFIRKLLVKETRKRLTIQEALRHPWITP 287
A+DFI +L ++ R+R T L+HPW+ P
Sbjct: 1212 NAARDFINVILQEDFRRRPTAATCLQHPWLQP 1243
>gi|9966875 calcium/calmodulin-dependent protein kinase ID isoform 1
[Homo sapiens]
Length = 357
Score = 219 bits (559), Expect = 2e-57
Identities = 121/343 (35%), Positives = 187/343 (54%), Gaps = 14/343 (4%)
Query: 17 QKVEDFYDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVSREEIEREVS 76
+ ++ ++ E LG+G F+ V EK+TG +A K I K+ + IE E++
Sbjct: 17 EDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKE-----SSIENEIA 71
Query: 77 ILRQVLHHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSFIKQILDG 136
+LR++ H N++ L D+YE+ + L+++LVSGGELFD + +K +E++A++ I+Q+LD
Sbjct: 72 VLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDA 131
Query: 137 VNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNIFGTPEFVAP 196
V YLH I H DLKPEN++ ++ I + DFGL+ G GTP +VAP
Sbjct: 132 VYYLHRMGIVHRDLKPENLLYYSQDEE-SKIMISDFGLSKMEGKGDVMSTACGTPGYVAP 190
Query: 197 EIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANITAVSYDFDEEFFSQTSE 256
E++ +P D WSIGVI YILL G PF + + I Y+FD ++ S+
Sbjct: 191 EVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISD 250
Query: 257 LAKDFIRKLLVKETRKRLTIQEALRHPWITPVDNQQAMVRRESVVNLENFRKQYVRRRWK 316
AKDFIR L+ K+ KR T ++A RHPWI D ESV RK + + +W+
Sbjct: 251 SAKDFIRNLMEKDPNKRYTCEQAARHPWIAG-DTALNKNIHESV--SAQIRKNFAKSKWR 307
Query: 317 LSFSIVSLCNHLTRSLMKKVHLRPDEDLRNCESDTEEDIARRK 359
+F+ ++ H M+K+HL D N + +A +K
Sbjct: 308 QAFNATAVVRH-----MRKLHLGSSLDSSNASVSSSLSLASQK 345
>gi|23943850 calcium/calmodulin-dependent protein kinase ID isoform
2 [Homo sapiens]
Length = 385
Score = 219 bits (559), Expect = 2e-57
Identities = 121/343 (35%), Positives = 187/343 (54%), Gaps = 14/343 (4%)
Query: 17 QKVEDFYDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVSREEIEREVS 76
+ ++ ++ E LG+G F+ V EK+TG +A K I K+ + IE E++
Sbjct: 17 EDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKE-----SSIENEIA 71
Query: 77 ILRQVLHHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSFIKQILDG 136
+LR++ H N++ L D+YE+ + L+++LVSGGELFD + +K +E++A++ I+Q+LD
Sbjct: 72 VLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDA 131
Query: 137 VNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNIFGTPEFVAP 196
V YLH I H DLKPEN++ ++ I + DFGL+ G GTP +VAP
Sbjct: 132 VYYLHRMGIVHRDLKPENLLYYSQDEE-SKIMISDFGLSKMEGKGDVMSTACGTPGYVAP 190
Query: 197 EIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANITAVSYDFDEEFFSQTSE 256
E++ +P D WSIGVI YILL G PF + + I Y+FD ++ S+
Sbjct: 191 EVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISD 250
Query: 257 LAKDFIRKLLVKETRKRLTIQEALRHPWITPVDNQQAMVRRESVVNLENFRKQYVRRRWK 316
AKDFIR L+ K+ KR T ++A RHPWI D ESV RK + + +W+
Sbjct: 251 SAKDFIRNLMEKDPNKRYTCEQAARHPWIAG-DTALNKNIHESV--SAQIRKNFAKSKWR 307
Query: 317 LSFSIVSLCNHLTRSLMKKVHLRPDEDLRNCESDTEEDIARRK 359
+F+ ++ H M+K+HL D N + +A +K
Sbjct: 308 QAFNATAVVRH-----MRKLHLGSSLDSSNASVSSSLSLASQK 345
>gi|209364621 pregnancy upregulated non-ubiquitously expressed CaM
kinase isoform b [Homo sapiens]
Length = 360
Score = 212 bits (540), Expect = 4e-55
Identities = 120/316 (37%), Positives = 182/316 (57%), Gaps = 14/316 (4%)
Query: 17 QKVEDFYDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVSREEIEREVS 76
+ + Y+I E LGSG F+ V +E+ + A K I K+ R V E E++
Sbjct: 26 EDISSVYEIRERLGSGAFSEVVLAQERGSAHLVALKCIPKKALRGKEALV-----ENEIA 80
Query: 77 ILRQVLHHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSFIKQILDG 136
+LR++ H N++ L DV+E+ + + L +ELV+GGELFD + ++ S +E++A+ + Q+L
Sbjct: 81 VLRRISHPNIVALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGA 140
Query: 137 VNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLI--DFGLAHEIEDGVEFKNIFGTPEFV 194
V+YLH+ I H DLKPEN++ P K++ DFGL+ +I+ G GTP +V
Sbjct: 141 VSYLHSLGIVHRDLKPENLLYAT---PFEDSKIMVSDFGLS-KIQAGNMLGTACGTPGYV 196
Query: 195 APEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANITAVSYDFDEEFFSQT 254
APE++ +P G D+W++GVI+YILL G PF ++ E + I SY+FD F+
Sbjct: 197 APELLEQKPYGKAVDVWALGVISYILLCGYPPFYDESDPELFSQILRASYEFDSPFWDDI 256
Query: 255 SELAKDFIRKLLVKETRKRLTIQEALRHPWITPVDNQQAMVRRESVVNLENFRKQYVRRR 314
SE AKDFIR LL ++ +KR T Q+ALRH WI+ A R E RK + R
Sbjct: 257 SESAKDFIRHLLERDPQKRFTCQQALRHLWIS---GDTAFDRDILGSVSEQIRKNFARTH 313
Query: 315 WKLSFSIVSLCNHLTR 330
WK +F+ S H+ +
Sbjct: 314 WKRAFNATSFLRHIRK 329
>gi|209364619 pregnancy upregulated non-ubiquitously expressed CaM
kinase isoform a [Homo sapiens]
Length = 426
Score = 212 bits (540), Expect = 4e-55
Identities = 120/316 (37%), Positives = 182/316 (57%), Gaps = 14/316 (4%)
Query: 17 QKVEDFYDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVSREEIEREVS 76
+ + Y+I E LGSG F+ V +E+ + A K I K+ R V E E++
Sbjct: 92 EDISSVYEIRERLGSGAFSEVVLAQERGSAHLVALKCIPKKALRGKEALV-----ENEIA 146
Query: 77 ILRQVLHHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSFIKQILDG 136
+LR++ H N++ L DV+E+ + + L +ELV+GGELFD + ++ S +E++A+ + Q+L
Sbjct: 147 VLRRISHPNIVALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGA 206
Query: 137 VNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLI--DFGLAHEIEDGVEFKNIFGTPEFV 194
V+YLH+ I H DLKPEN++ P K++ DFGL+ +I+ G GTP +V
Sbjct: 207 VSYLHSLGIVHRDLKPENLLYAT---PFEDSKIMVSDFGLS-KIQAGNMLGTACGTPGYV 262
Query: 195 APEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANITAVSYDFDEEFFSQT 254
APE++ +P G D+W++GVI+YILL G PF ++ E + I SY+FD F+
Sbjct: 263 APELLEQKPYGKAVDVWALGVISYILLCGYPPFYDESDPELFSQILRASYEFDSPFWDDI 322
Query: 255 SELAKDFIRKLLVKETRKRLTIQEALRHPWITPVDNQQAMVRRESVVNLENFRKQYVRRR 314
SE AKDFIR LL ++ +KR T Q+ALRH WI+ A R E RK + R
Sbjct: 323 SESAKDFIRHLLERDPQKRFTCQQALRHLWIS---GDTAFDRDILGSVSEQIRKNFARTH 379
Query: 315 WKLSFSIVSLCNHLTR 330
WK +F+ S H+ +
Sbjct: 380 WKRAFNATSFLRHIRK 395
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 211 bits (536), Expect = 1e-54
Identities = 102/264 (38%), Positives = 164/264 (62%), Gaps = 10/264 (3%)
Query: 23 YDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVSREEIEREVSILRQVL 82
Y I E+LG G+F IV +C E S+ Y AKF+K + G + +++E+SIL
Sbjct: 31251 YMIAEDLGRGEFGIVHRCVETSSKKTYMAKFVKVK-------GTDQVLVKKEISILNIAR 31303
Query: 83 HHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKE-SLSEEEATSFIKQILDGVNYLH 141
H N++ LH+ +E+ ++V+I E +SG ++F+ + L+E E S++ Q+ + + +LH
Sbjct: 31304 HRNILHLHESFESMEELVMIFEFISGLDIFERINTSAFELNEREIVSYVHQVCEALQFLH 31363
Query: 142 TKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNIFGTPEFVAPEIVNY 201
+ I HFD++PENI+ + IK+I+FG A +++ G F+ +F PE+ APE+ +
Sbjct: 31364 SHNIGHFDIRPENIIYQTRRSST--IKIIEFGQARQLKPGDNFRLLFTAPEYYAPEVHQH 31421
Query: 202 EPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANITAVSYDFDEEFFSQTSELAKDF 261
+ + DMWS+G + Y+LLSG +PFL +T Q+ + NI Y FDEE F + S A DF
Sbjct: 31422 DVVSTATDMWSLGTLVYVLLSGINPFLAETNQQIIENIMNAEYTFDEEAFKEISIEAMDF 31481
Query: 262 IRKLLVKETRKRLTIQEALRHPWI 285
+ +LLVKE + R+T EAL+HPW+
Sbjct: 31482 VDRLLVKERKSRMTASEALQHPWL 31505
>gi|110349717 titin isoform novex-2 [Homo sapiens]
Length = 27118
Score = 211 bits (536), Expect = 1e-54
Identities = 102/264 (38%), Positives = 164/264 (62%), Gaps = 10/264 (3%)
Query: 23 YDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVSREEIEREVSILRQVL 82
Y I E+LG G+F IV +C E S+ Y AKF+K + G + +++E+SIL
Sbjct: 24946 YMIAEDLGRGEFGIVHRCVETSSKKTYMAKFVKVK-------GTDQVLVKKEISILNIAR 24998
Query: 83 HHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKE-SLSEEEATSFIKQILDGVNYLH 141
H N++ LH+ +E+ ++V+I E +SG ++F+ + L+E E S++ Q+ + + +LH
Sbjct: 24999 HRNILHLHESFESMEELVMIFEFISGLDIFERINTSAFELNEREIVSYVHQVCEALQFLH 25058
Query: 142 TKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNIFGTPEFVAPEIVNY 201
+ I HFD++PENI+ + IK+I+FG A +++ G F+ +F PE+ APE+ +
Sbjct: 25059 SHNIGHFDIRPENIIYQTRRSST--IKIIEFGQARQLKPGDNFRLLFTAPEYYAPEVHQH 25116
Query: 202 EPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANITAVSYDFDEEFFSQTSELAKDF 261
+ + DMWS+G + Y+LLSG +PFL +T Q+ + NI Y FDEE F + S A DF
Sbjct: 25117 DVVSTATDMWSLGTLVYVLLSGINPFLAETNQQIIENIMNAEYTFDEEAFKEISIEAMDF 25176
Query: 262 IRKLLVKETRKRLTIQEALRHPWI 285
+ +LLVKE + R+T EAL+HPW+
Sbjct: 25177 VDRLLVKERKSRMTASEALQHPWL 25200
>gi|110349713 titin isoform novex-1 [Homo sapiens]
Length = 27051
Score = 211 bits (536), Expect = 1e-54
Identities = 102/264 (38%), Positives = 164/264 (62%), Gaps = 10/264 (3%)
Query: 23 YDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVSREEIEREVSILRQVL 82
Y I E+LG G+F IV +C E S+ Y AKF+K + G + +++E+SIL
Sbjct: 24879 YMIAEDLGRGEFGIVHRCVETSSKKTYMAKFVKVK-------GTDQVLVKKEISILNIAR 24931
Query: 83 HHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKE-SLSEEEATSFIKQILDGVNYLH 141
H N++ LH+ +E+ ++V+I E +SG ++F+ + L+E E S++ Q+ + + +LH
Sbjct: 24932 HRNILHLHESFESMEELVMIFEFISGLDIFERINTSAFELNEREIVSYVHQVCEALQFLH 24991
Query: 142 TKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNIFGTPEFVAPEIVNY 201
+ I HFD++PENI+ + IK+I+FG A +++ G F+ +F PE+ APE+ +
Sbjct: 24992 SHNIGHFDIRPENIIYQTRRSST--IKIIEFGQARQLKPGDNFRLLFTAPEYYAPEVHQH 25049
Query: 202 EPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANITAVSYDFDEEFFSQTSELAKDF 261
+ + DMWS+G + Y+LLSG +PFL +T Q+ + NI Y FDEE F + S A DF
Sbjct: 25050 DVVSTATDMWSLGTLVYVLLSGINPFLAETNQQIIENIMNAEYTFDEEAFKEISIEAMDF 25109
Query: 262 IRKLLVKETRKRLTIQEALRHPWI 285
+ +LLVKE + R+T EAL+HPW+
Sbjct: 25110 VDRLLVKERKSRMTASEALQHPWL 25133
>gi|110349715 titin isoform N2-B [Homo sapiens]
Length = 26926
Score = 211 bits (536), Expect = 1e-54
Identities = 102/264 (38%), Positives = 164/264 (62%), Gaps = 10/264 (3%)
Query: 23 YDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVSREEIEREVSILRQVL 82
Y I E+LG G+F IV +C E S+ Y AKF+K + G + +++E+SIL
Sbjct: 24754 YMIAEDLGRGEFGIVHRCVETSSKKTYMAKFVKVK-------GTDQVLVKKEISILNIAR 24806
Query: 83 HHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKE-SLSEEEATSFIKQILDGVNYLH 141
H N++ LH+ +E+ ++V+I E +SG ++F+ + L+E E S++ Q+ + + +LH
Sbjct: 24807 HRNILHLHESFESMEELVMIFEFISGLDIFERINTSAFELNEREIVSYVHQVCEALQFLH 24866
Query: 142 TKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNIFGTPEFVAPEIVNY 201
+ I HFD++PENI+ + IK+I+FG A +++ G F+ +F PE+ APE+ +
Sbjct: 24867 SHNIGHFDIRPENIIYQTRRSST--IKIIEFGQARQLKPGDNFRLLFTAPEYYAPEVHQH 24924
Query: 202 EPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANITAVSYDFDEEFFSQTSELAKDF 261
+ + DMWS+G + Y+LLSG +PFL +T Q+ + NI Y FDEE F + S A DF
Sbjct: 24925 DVVSTATDMWSLGTLVYVLLSGINPFLAETNQQIIENIMNAEYTFDEEAFKEISIEAMDF 24984
Query: 262 IRKLLVKETRKRLTIQEALRHPWI 285
+ +LLVKE + R+T EAL+HPW+
Sbjct: 24985 VDRLLVKERKSRMTASEALQHPWL 25008
>gi|26667183 calcium/calmodulin-dependent protein kinase II delta
isoform 1 [Homo sapiens]
Length = 478
Score = 208 bits (530), Expect = 5e-54
Identities = 128/347 (36%), Positives = 187/347 (53%), Gaps = 19/347 (5%)
Query: 21 DFYDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVSREEIEREVSILRQ 80
D Y + EELG G F++V++C + TG EYAAK I ++ A +++ERE I R
Sbjct: 12 DEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSAR----DHQKLEREARICRL 67
Query: 81 VLHHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSFIKQILDGVNYL 140
+ H N++ LHD L+ +LV+GGELF+ + +E SE +A+ I+QIL+ VN+
Sbjct: 68 LKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHC 127
Query: 141 HTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIE-DGVEFKNIFGTPEFVAPEIV 199
H I H DLKPEN++L K+ +KL DFGLA E++ D + GTP +++PE++
Sbjct: 128 HLNGIVHRDLKPENLLLASKSKGAA-VKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVL 186
Query: 200 NYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANITAVSYDFDEEFFSQTSELAK 259
+P G DMW+ GVI YILL G PF + + I A +YDF + + AK
Sbjct: 187 RKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAK 246
Query: 260 DFIRKLLVKETRKRLTIQEALRHPWITPVDNQQAMVRRESVVNLENFRKQYVRRRWKLSF 319
D I K+L KR+T EAL+HPWI +M+ R+ V+ +K RR+ K +
Sbjct: 247 DLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDC--LKKFNARRKLKGAI 304
Query: 320 SIVSLCNH---LTRSLMKKVHLRPDEDLRNCESDT----EEDIARRK 359
L +SL+KK PD + ES +ED+ RK
Sbjct: 305 LTTMLATRNFSAAKSLLKK----PDGVKESTESSNTTIEDEDVKARK 347
>gi|26667186 calcium/calmodulin-dependent protein kinase II delta
isoform 1 [Homo sapiens]
Length = 478
Score = 208 bits (530), Expect = 5e-54
Identities = 128/347 (36%), Positives = 187/347 (53%), Gaps = 19/347 (5%)
Query: 21 DFYDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVSREEIEREVSILRQ 80
D Y + EELG G F++V++C + TG EYAAK I ++ A +++ERE I R
Sbjct: 12 DEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSAR----DHQKLEREARICRL 67
Query: 81 VLHHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSFIKQILDGVNYL 140
+ H N++ LHD L+ +LV+GGELF+ + +E SE +A+ I+QIL+ VN+
Sbjct: 68 LKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHC 127
Query: 141 HTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIE-DGVEFKNIFGTPEFVAPEIV 199
H I H DLKPEN++L K+ +KL DFGLA E++ D + GTP +++PE++
Sbjct: 128 HLNGIVHRDLKPENLLLASKSKGAA-VKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVL 186
Query: 200 NYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANITAVSYDFDEEFFSQTSELAK 259
+P G DMW+ GVI YILL G PF + + I A +YDF + + AK
Sbjct: 187 RKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAK 246
Query: 260 DFIRKLLVKETRKRLTIQEALRHPWITPVDNQQAMVRRESVVNLENFRKQYVRRRWKLSF 319
D I K+L KR+T EAL+HPWI +M+ R+ V+ +K RR+ K +
Sbjct: 247 DLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDC--LKKFNARRKLKGAI 304
Query: 320 SIVSLCNH---LTRSLMKKVHLRPDEDLRNCESDT----EEDIARRK 359
L +SL+KK PD + ES +ED+ RK
Sbjct: 305 LTTMLATRNFSAAKSLLKK----PDGVKESTESSNTTIEDEDVKARK 347
>gi|26667189 calcium/calmodulin-dependent protein kinase II delta
isoform 2 [Homo sapiens]
Length = 478
Score = 208 bits (530), Expect = 5e-54
Identities = 128/347 (36%), Positives = 187/347 (53%), Gaps = 19/347 (5%)
Query: 21 DFYDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVSREEIEREVSILRQ 80
D Y + EELG G F++V++C + TG EYAAK I ++ A +++ERE I R
Sbjct: 12 DEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSAR----DHQKLEREARICRL 67
Query: 81 VLHHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSFIKQILDGVNYL 140
+ H N++ LHD L+ +LV+GGELF+ + +E SE +A+ I+QIL+ VN+
Sbjct: 68 LKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHC 127
Query: 141 HTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIE-DGVEFKNIFGTPEFVAPEIV 199
H I H DLKPEN++L K+ +KL DFGLA E++ D + GTP +++PE++
Sbjct: 128 HLNGIVHRDLKPENLLLASKSKGAA-VKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVL 186
Query: 200 NYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANITAVSYDFDEEFFSQTSELAK 259
+P G DMW+ GVI YILL G PF + + I A +YDF + + AK
Sbjct: 187 RKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAK 246
Query: 260 DFIRKLLVKETRKRLTIQEALRHPWITPVDNQQAMVRRESVVNLENFRKQYVRRRWKLSF 319
D I K+L KR+T EAL+HPWI +M+ R+ V+ +K RR+ K +
Sbjct: 247 DLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDC--LKKFNARRKLKGAI 304
Query: 320 SIVSLCNH---LTRSLMKKVHLRPDEDLRNCESDT----EEDIARRK 359
L +SL+KK PD + ES +ED+ RK
Sbjct: 305 LTTMLATRNFSAAKSLLKK----PDGVKESTESSNTTIEDEDVKARK 347
>gi|26667180 calcium/calmodulin-dependent protein kinase II delta
isoform 3 [Homo sapiens]
Length = 499
Score = 208 bits (530), Expect = 5e-54
Identities = 128/347 (36%), Positives = 187/347 (53%), Gaps = 19/347 (5%)
Query: 21 DFYDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVSREEIEREVSILRQ 80
D Y + EELG G F++V++C + TG EYAAK I ++ A +++ERE I R
Sbjct: 12 DEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSAR----DHQKLEREARICRL 67
Query: 81 VLHHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSFIKQILDGVNYL 140
+ H N++ LHD L+ +LV+GGELF+ + +E SE +A+ I+QIL+ VN+
Sbjct: 68 LKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHC 127
Query: 141 HTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIE-DGVEFKNIFGTPEFVAPEIV 199
H I H DLKPEN++L K+ +KL DFGLA E++ D + GTP +++PE++
Sbjct: 128 HLNGIVHRDLKPENLLLASKSKGAA-VKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVL 186
Query: 200 NYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANITAVSYDFDEEFFSQTSELAK 259
+P G DMW+ GVI YILL G PF + + I A +YDF + + AK
Sbjct: 187 RKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAK 246
Query: 260 DFIRKLLVKETRKRLTIQEALRHPWITPVDNQQAMVRRESVVNLENFRKQYVRRRWKLSF 319
D I K+L KR+T EAL+HPWI +M+ R+ V+ +K RR+ K +
Sbjct: 247 DLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDC--LKKFNARRKLKGAI 304
Query: 320 SIVSLCNH---LTRSLMKKVHLRPDEDLRNCESDT----EEDIARRK 359
L +SL+KK PD + ES +ED+ RK
Sbjct: 305 LTTMLATRNFSAAKSLLKK----PDGVKESTESSNTTIEDEDVKARK 347
>gi|14196445 calcium/calmodulin-dependent protein kinase IG [Homo
sapiens]
Length = 476
Score = 208 bits (530), Expect = 5e-54
Identities = 123/330 (37%), Positives = 189/330 (57%), Gaps = 15/330 (4%)
Query: 27 EELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVSREEIEREVSILRQVLHHNV 86
E LGSG F+ V +++ TG +A K IKK S A R +E E+++L+++ H N+
Sbjct: 27 EVLGSGAFSEVFLVKQRLTGKLFALKCIKK--SPAFRDS----SLENEIAVLKKIKHENI 80
Query: 87 ITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSFIKQILDGVNYLHTKKIA 146
+TL D+YE+ T L+++LVSGGELFD + ++ +E++A+ I+Q+L V YLH I
Sbjct: 81 VTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYLHENGIV 140
Query: 147 HFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNIFGTPEFVAPEIVNYEPLGL 206
H DLKPEN++ L I + DFGL+ ++G+ GTP +VAPE++ +P
Sbjct: 141 HRDLKPENLLYLTPE-ENSKIMITDFGLSKMEQNGI-MSTACGTPGYVAPEVLAQKPYSK 198
Query: 207 EADMWSIGVITYILLSGASPFLGDTKQETLANITAVSYDFDEEFFSQTSELAKDFIRKLL 266
D WSIGVITYILL G PF +T+ + I Y+F+ F+ SE AKDFI LL
Sbjct: 199 AVDCWSIGVITYILLCGYPPFYEETESKLFEKIKEGYYEFESPFWDDISESAKDFICHLL 258
Query: 267 VKETRKRLTIQEALRHPWITPVDNQQAMVRRESVVNLENFRKQYVRRRWKLSFSIVSLCN 326
K+ +R T ++AL HPWI D A+ R +K + + +W+ +F+ ++ +
Sbjct: 259 EKDPNERYTCEKALSHPWI---DGNTALHRDIYPSVSLQIQKNFAKSKWRQAFNAAAVVH 315
Query: 327 HLTRSLMKKVH---LRPDEDLRNCESDTEE 353
H+ R L +H +RP+ + R E+ E
Sbjct: 316 HM-RKLHMNLHSPGVRPEVENRPPETQASE 344
>gi|212549753 calcium/calmodulin-dependent protein kinase II delta
isoform 5 [Homo sapiens]
Length = 492
Score = 207 bits (526), Expect = 2e-53
Identities = 129/357 (36%), Positives = 189/357 (52%), Gaps = 25/357 (7%)
Query: 21 DFYDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVSREEIEREVSILRQ 80
D Y + EELG G F++V++C + TG EYAAK I ++ A +++ERE I R
Sbjct: 12 DEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSAR----DHQKLEREARICRL 67
Query: 81 VLHHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSFIKQILDGVNYL 140
+ H N++ LHD L+ +LV+GGELF+ + +E SE +A+ I+QIL+ VN+
Sbjct: 68 LKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHC 127
Query: 141 HTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIE-DGVEFKNIFGTPEFVAPEIV 199
H I H DLKPEN++L K+ +KL DFGLA E++ D + GTP +++PE++
Sbjct: 128 HLNGIVHRDLKPENLLLASKSKGAA-VKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVL 186
Query: 200 NYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANITAVSYDFDEEFFSQTSELAK 259
+P G DMW+ GVI YILL G PF + + I A +YDF + + AK
Sbjct: 187 RKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAK 246
Query: 260 DFIRKLLVKETRKRLTIQEALRHPWITPVDNQQAMVRRESVVNLENFRKQYVRRRWKLSF 319
D I K+L KR+T EAL+HPWI +M+ R+ V+ +K RR+ K +
Sbjct: 247 DLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDC--LKKFNARRKLKGAI 304
Query: 320 SIVSLCNH---LTRSLMKK----------VHLRPDEDLRNCESDT----EEDIARRK 359
L +SL+KK V PD + + ES +ED+ RK
Sbjct: 305 LTTMLATRNFSAAKSLLKKPDGVKEPQTTVIHNPDGNKESTESSNTTIEDEDVKARK 361
>gi|4502557 calcium/calmodulin-dependent protein kinase IV [Homo
sapiens]
Length = 473
Score = 206 bits (523), Expect = 4e-53
Identities = 111/269 (41%), Positives = 161/269 (59%), Gaps = 10/269 (3%)
Query: 19 VEDFYDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVSREEIEREVSIL 78
+ DF+++ ELG G +IV +C++K T YA K +KK V ++ + E+ +L
Sbjct: 42 LSDFFEVESELGRGATSIVYRCKQKGTQKPYALKVLKKT--------VDKKIVRTEIGVL 93
Query: 79 RQVLHHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSFIKQILDGVN 138
++ H N+I L +++E T++ L+LELV+GGELFD + +K SE +A +KQIL+ V
Sbjct: 94 LRLSHPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVA 153
Query: 139 YLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNIFGTPEFVAPEI 198
YLH I H DLKPEN +L P +K+ DFGL+ +E V K + GTP + APEI
Sbjct: 154 YLHENGIVHRDLKPEN-LLYATPAPDAPLKIADFGLSKIVEHQVLMKTVCGTPGYCAPEI 212
Query: 199 VNYEPLGLEADMWSIGVITYILLSGASPFLGDT-KQETLANITAVSYDFDEEFFSQTSEL 257
+ G E DMWS+G+ITYILL G PF + Q I Y F ++ + S
Sbjct: 213 LRGCAYGPEVDMWSVGIITYILLCGFEPFYDERGDQFMFRRILNCEYYFISPWWDEVSLN 272
Query: 258 AKDFIRKLLVKETRKRLTIQEALRHPWIT 286
AKD +RKL+V + +KRLT +AL+HPW+T
Sbjct: 273 AKDLVRKLIVLDPKKRLTTFQALQHPWVT 301
>gi|212549756 calcium/calmodulin-dependent protein kinase II delta
isoform 4 [Homo sapiens]
Length = 489
Score = 205 bits (521), Expect = 6e-53
Identities = 120/319 (37%), Positives = 176/319 (55%), Gaps = 11/319 (3%)
Query: 21 DFYDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVSREEIEREVSILRQ 80
D Y + EELG G F++V++C + TG EYAAK I ++ A +++ERE I R
Sbjct: 12 DEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSAR----DHQKLEREARICRL 67
Query: 81 VLHHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSFIKQILDGVNYL 140
+ H N++ LHD L+ +LV+GGELF+ + +E SE +A+ I+QIL+ VN+
Sbjct: 68 LKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHC 127
Query: 141 HTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIE-DGVEFKNIFGTPEFVAPEIV 199
H I H DLKPEN++L K+ +KL DFGLA E++ D + GTP +++PE++
Sbjct: 128 HLNGIVHRDLKPENLLLASKSKGAA-VKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVL 186
Query: 200 NYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANITAVSYDFDEEFFSQTSELAK 259
+P G DMW+ GVI YILL G PF + + I A +YDF + + AK
Sbjct: 187 RKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAK 246
Query: 260 DFIRKLLVKETRKRLTIQEALRHPWITPVDNQQAMVRRESVVNLENFRKQYVRRRWKLSF 319
D I K+L KR+T EAL+HPWI +M+ R+ V+ +K RR+ K +
Sbjct: 247 DLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDC--LKKFNARRKLKGAI 304
Query: 320 SIVSLCNH---LTRSLMKK 335
L +SL+KK
Sbjct: 305 LTTMLATRNFSAAKSLLKK 323
>gi|4502553 calcium/calmodulin-dependent protein kinase I [Homo
sapiens]
Length = 370
Score = 205 bits (521), Expect = 6e-53
Identities = 113/316 (35%), Positives = 175/316 (55%), Gaps = 13/316 (4%)
Query: 17 QKVEDFYDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVSREEIEREVS 76
+ + D YD + LG+G F+ V +K T A K I K ++ + G +E E++
Sbjct: 14 EDIRDIYDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAK-EALEGKEG----SMENEIA 68
Query: 77 ILRQVLHHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSFIKQILDG 136
+L ++ H N++ L D+YE+ + LI++LVSGGELFD + +K +E +A+ I Q+LD
Sbjct: 69 VLHKIKHPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDA 128
Query: 137 VNYLHTKKIAHFDLKPENIML--LDKNIPIPHIKLIDFGLAHEIEDGVEFKNIFGTPEFV 194
V YLH I H DLKPEN++ LD++ I + DFGL+ + G GTP +V
Sbjct: 129 VKYLHDLGIVHRDLKPENLLYYSLDED---SKIMISDFGLSKMEDPGSVLSTACGTPGYV 185
Query: 195 APEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANITAVSYDFDEEFFSQT 254
APE++ +P D WSIGVI YILL G PF + + I Y+FD ++
Sbjct: 186 APEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDI 245
Query: 255 SELAKDFIRKLLVKETRKRLTIQEALRHPWITPVDNQQAMVRRESVVNLENFRKQYVRRR 314
S+ AKDFIR L+ K+ KR T ++AL+HPWI A+ + E +K + + +
Sbjct: 246 SDSAKDFIRHLMEKDPEKRFTCEQALQHPWIA---GDTALDKNIHQSVSEQIKKNFAKSK 302
Query: 315 WKLSFSIVSLCNHLTR 330
WK +F+ ++ H+ +
Sbjct: 303 WKQAFNATAVVRHMRK 318
>gi|157785645 SPEG complex locus [Homo sapiens]
Length = 3267
Score = 203 bits (517), Expect = 2e-52
Identities = 117/331 (35%), Positives = 193/331 (58%), Gaps = 19/331 (5%)
Query: 12 EPFKQQKVEDFYDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKR-QSRASRRGVSREE 70
E + +++ DFYDI +E+G G F+ +++ E+S+GLE+AAKFI + + +AS R
Sbjct: 1590 EDHRGRRLSDFYDIHQEIGRGAFSYLRRIVERSSGLEFAAKFIPSQAKPKASAR------ 1643
Query: 71 IEREVSILRQVLHHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSFI 130
RE +L ++ H V+ H+ +E R +V++ EL + EL + +A+K ++ E E +++
Sbjct: 1644 --REARLLARLQHDCVLYFHEAFERRRGLVIVTELCTE-ELLERIARKPTVCESEIRAYM 1700
Query: 131 KQILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNIFGT 190
+Q+L+G++YLH + H D+KPEN+++ D +++ DFG A E+ G +GT
Sbjct: 1701 RQVLEGIHYLHQSHVLHLDVKPENLLVWDGAAGEQQVRICDFGNAQELTPGEPQYCQYGT 1760
Query: 191 PEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANITAVSYDFDEEF 250
PEFVAPEIVN P+ D+W +GV+ ++ L+G SPF+G+ + TL NI + F+E
Sbjct: 1761 PEFVAPEIVNQSPVSGVTDIWPVGVVAFLCLTGISPFVGENDRTTLMNIRNYNVAFEETT 1820
Query: 251 FSQTSELAKDFIRKLLVKETRKRLTIQEALRHPWITPVDNQQAMVRRESVVNLENFRKQY 310
F S A+ F+ K+LV++ R R T +E L HPW QA S +L+ F
Sbjct: 1821 FLSLSREARGFLIKVLVQD-RLRPTAEETLEHPWF----KTQAKGAEVSTDHLKLFLS-- 1873
Query: 311 VRRRWKLSFSIVSLCNHLTRSLMKKVHLRPD 341
RRRW+ S I C+ + R + + + P+
Sbjct: 1874 -RRRWQRS-QISYKCHLVLRPIPELLRAPPE 1902
Score = 162 bits (411), Expect = 3e-40
Identities = 100/311 (32%), Positives = 160/311 (51%), Gaps = 19/311 (6%)
Query: 9 PNMEPFKQQKVEDFYDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVSR 68
P +Q + Y EE G+F +V+ CRE +TG + AK + +
Sbjct: 2952 PEGTTLRQGPPQKPYTFLEEKARGRFGVVRACRENATGRTFVAKIVPYAAE-------GK 3004
Query: 69 EEIEREVSILRQVLHHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATS 128
+ +E +LR + H +++LH+ Y +VLI E EL L+ + SE++ +
Sbjct: 3005 RRVLQEYEVLRTLHHERIMSLHEAYITPRYLVLIAESCGNRELLCGLSDRFRYSEDDVAT 3064
Query: 129 FIKQILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGV--EFKN 186
++ Q+L G++YLH + H D+KP+N++L N +K++DFG A +
Sbjct: 3065 YMVQLLQGLDYLHGHHVLHLDIKPDNLLLAPDNA----LKIVDFGSAQPYNPQALRPLGH 3120
Query: 187 IFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANITAVSYDF 246
GT EF+APE+V EP+G D+W GV+TYI+LSG SPF QET A I +D
Sbjct: 3121 RTGTLEFMAPEMVKGEPIGSATDIWGAGVLTYIMLSGRSPFYEPDPQETEARIVGGRFD- 3179
Query: 247 DEEFFSQTSELAKDFIRKLLVKETRKRLTIQEALRHPWITPVDNQQAMVRRESVVNLENF 306
+ + TS+ A F+RK+L R ++Q+ L HPW+ D +RR+++ N
Sbjct: 3180 AFQLYPNTSQSATLFLRKVLSVHPWSRPSLQDCLAHPWLQ--DAYLMKLRRQTLTFTTNR 3237
Query: 307 RKQYV---RRR 314
K+++ RRR
Sbjct: 3238 LKEFLGEQRRR 3248
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.385
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,843,973
Number of Sequences: 37866
Number of extensions: 545737
Number of successful extensions: 4019
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 614
Number of HSP's successfully gapped in prelim test: 179
Number of HSP's that attempted gapping in prelim test: 1678
Number of HSP's gapped (non-prelim): 976
length of query: 370
length of database: 18,247,518
effective HSP length: 104
effective length of query: 266
effective length of database: 14,309,454
effective search space: 3806314764
effective search space used: 3806314764
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.