BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|14591928 Sec23 homolog B [Homo sapiens] (767 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|14591924 Sec23 homolog B [Homo sapiens] 1565 0.0 gi|14591926 Sec23 homolog B [Homo sapiens] 1565 0.0 gi|14591928 Sec23 homolog B [Homo sapiens] 1565 0.0 gi|38202214 SEC23-related protein A [Homo sapiens] 1353 0.0 gi|112382214 SEC24 (S. cerevisiae) homolog B isoform b [Homo sap... 83 8e-16 gi|112382212 SEC24 (S. cerevisiae) homolog B isoform a [Homo sap... 83 8e-16 gi|116174780 SEC24 related gene family, member A [Homo sapiens] 75 2e-13 gi|38373671 SEC24-related protein C [Homo sapiens] 74 7e-13 gi|38373669 SEC24-related protein C [Homo sapiens] 74 7e-13 gi|190343021 Sec24-related protein D [Homo sapiens] 64 5e-10 gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens] 32 2.9 gi|166362728 epidermal growth factor (beta-urogastrone) [Homo sa... 30 6.5 gi|222352129 von Willebrand factor A domain containing 5B2 [Homo... 30 8.4 gi|4503963 glucosaminyl (N-acetyl) transferase 2, I-branching en... 30 8.4 >gi|14591924 Sec23 homolog B [Homo sapiens] Length = 767 Score = 1565 bits (4053), Expect = 0.0 Identities = 767/767 (100%), Positives = 767/767 (100%) Query: 1 MATYLEFIQQNEERDGVRFSWNVWPSSRLEATRMVVPLACLLTPLKERPDLPPVQYEPVL 60 MATYLEFIQQNEERDGVRFSWNVWPSSRLEATRMVVPLACLLTPLKERPDLPPVQYEPVL Sbjct: 1 MATYLEFIQQNEERDGVRFSWNVWPSSRLEATRMVVPLACLLTPLKERPDLPPVQYEPVL 60 Query: 61 CSRPTCKAVLNPLCQVDYRAKLWACNFCFQRNQFPPAYGGISEVNQPAELMPQFSTIEYV 120 CSRPTCKAVLNPLCQVDYRAKLWACNFCFQRNQFPPAYGGISEVNQPAELMPQFSTIEYV Sbjct: 61 CSRPTCKAVLNPLCQVDYRAKLWACNFCFQRNQFPPAYGGISEVNQPAELMPQFSTIEYV 120 Query: 121 IQRGAQSPLIFLYVVDTCLEEDDLQALKESLQMSLSLLPPDALVGLITFGRMVQVHELSC 180 IQRGAQSPLIFLYVVDTCLEEDDLQALKESLQMSLSLLPPDALVGLITFGRMVQVHELSC Sbjct: 121 IQRGAQSPLIFLYVVDTCLEEDDLQALKESLQMSLSLLPPDALVGLITFGRMVQVHELSC 180 Query: 181 EGISKSYVFRGTKDLTAKQIQDMLGLTKPAMPMQQARPAQPQEHPFASSRFLQPVHKIDM 240 EGISKSYVFRGTKDLTAKQIQDMLGLTKPAMPMQQARPAQPQEHPFASSRFLQPVHKIDM Sbjct: 181 EGISKSYVFRGTKDLTAKQIQDMLGLTKPAMPMQQARPAQPQEHPFASSRFLQPVHKIDM 240 Query: 241 NLTDLLGELQRDPWPVTQGKRPLRSTGVALSIAVGLLEGTFPNTGARIMLFTGGPPTQGP 300 NLTDLLGELQRDPWPVTQGKRPLRSTGVALSIAVGLLEGTFPNTGARIMLFTGGPPTQGP Sbjct: 241 NLTDLLGELQRDPWPVTQGKRPLRSTGVALSIAVGLLEGTFPNTGARIMLFTGGPPTQGP 300 Query: 301 GMVVGDELKIPIRSWHDIEKDNARFMKKATKHYEMLANRTAANGHCIDIYACALDQTGLL 360 GMVVGDELKIPIRSWHDIEKDNARFMKKATKHYEMLANRTAANGHCIDIYACALDQTGLL Sbjct: 301 GMVVGDELKIPIRSWHDIEKDNARFMKKATKHYEMLANRTAANGHCIDIYACALDQTGLL 360 Query: 361 EMKCCANLTGGYMVMGDSFNTSLFKQTFQRIFTKDFNGDFRMAFGATLDVKTSRELKIAG 420 EMKCCANLTGGYMVMGDSFNTSLFKQTFQRIFTKDFNGDFRMAFGATLDVKTSRELKIAG Sbjct: 361 EMKCCANLTGGYMVMGDSFNTSLFKQTFQRIFTKDFNGDFRMAFGATLDVKTSRELKIAG 420 Query: 421 AIGPCVSLNVKGPCVSENELGVGGTSQWKICGLDPTSTLGIYFEVVNQHNTPIPQGGRGA 480 AIGPCVSLNVKGPCVSENELGVGGTSQWKICGLDPTSTLGIYFEVVNQHNTPIPQGGRGA Sbjct: 421 AIGPCVSLNVKGPCVSENELGVGGTSQWKICGLDPTSTLGIYFEVVNQHNTPIPQGGRGA 480 Query: 481 IQFVTHYQHSSTQRRIRVTTIARNWADVQSQLRHIEAAFDQEAAAVLMARLGVFRAESEE 540 IQFVTHYQHSSTQRRIRVTTIARNWADVQSQLRHIEAAFDQEAAAVLMARLGVFRAESEE Sbjct: 481 IQFVTHYQHSSTQRRIRVTTIARNWADVQSQLRHIEAAFDQEAAAVLMARLGVFRAESEE 540 Query: 541 GPDVLRWLDRQLIRLCQKFGQYNKEDPTSFRLSDSFSLYPQFMFHLRRSPFLQVFNNSPD 600 GPDVLRWLDRQLIRLCQKFGQYNKEDPTSFRLSDSFSLYPQFMFHLRRSPFLQVFNNSPD Sbjct: 541 GPDVLRWLDRQLIRLCQKFGQYNKEDPTSFRLSDSFSLYPQFMFHLRRSPFLQVFNNSPD 600 Query: 601 ESSYYRHHFARQDLTQSLIMIQPILYSYSFHGPPEPVLLDSSSILADRILLMDTFFQIVI 660 ESSYYRHHFARQDLTQSLIMIQPILYSYSFHGPPEPVLLDSSSILADRILLMDTFFQIVI Sbjct: 601 ESSYYRHHFARQDLTQSLIMIQPILYSYSFHGPPEPVLLDSSSILADRILLMDTFFQIVI 660 Query: 661 YLGETIAQWRKAGYQDMPEYENFKHLLQAPLDDAQEILQARFPMPRYINTEHGGSQARFL 720 YLGETIAQWRKAGYQDMPEYENFKHLLQAPLDDAQEILQARFPMPRYINTEHGGSQARFL Sbjct: 661 YLGETIAQWRKAGYQDMPEYENFKHLLQAPLDDAQEILQARFPMPRYINTEHGGSQARFL 720 Query: 721 LSKVNPSQTHNNLYAWGQETGAPILTDDVSLQVFMDHLKKLAVSSAC 767 LSKVNPSQTHNNLYAWGQETGAPILTDDVSLQVFMDHLKKLAVSSAC Sbjct: 721 LSKVNPSQTHNNLYAWGQETGAPILTDDVSLQVFMDHLKKLAVSSAC 767 >gi|14591926 Sec23 homolog B [Homo sapiens] Length = 767 Score = 1565 bits (4053), Expect = 0.0 Identities = 767/767 (100%), Positives = 767/767 (100%) Query: 1 MATYLEFIQQNEERDGVRFSWNVWPSSRLEATRMVVPLACLLTPLKERPDLPPVQYEPVL 60 MATYLEFIQQNEERDGVRFSWNVWPSSRLEATRMVVPLACLLTPLKERPDLPPVQYEPVL Sbjct: 1 MATYLEFIQQNEERDGVRFSWNVWPSSRLEATRMVVPLACLLTPLKERPDLPPVQYEPVL 60 Query: 61 CSRPTCKAVLNPLCQVDYRAKLWACNFCFQRNQFPPAYGGISEVNQPAELMPQFSTIEYV 120 CSRPTCKAVLNPLCQVDYRAKLWACNFCFQRNQFPPAYGGISEVNQPAELMPQFSTIEYV Sbjct: 61 CSRPTCKAVLNPLCQVDYRAKLWACNFCFQRNQFPPAYGGISEVNQPAELMPQFSTIEYV 120 Query: 121 IQRGAQSPLIFLYVVDTCLEEDDLQALKESLQMSLSLLPPDALVGLITFGRMVQVHELSC 180 IQRGAQSPLIFLYVVDTCLEEDDLQALKESLQMSLSLLPPDALVGLITFGRMVQVHELSC Sbjct: 121 IQRGAQSPLIFLYVVDTCLEEDDLQALKESLQMSLSLLPPDALVGLITFGRMVQVHELSC 180 Query: 181 EGISKSYVFRGTKDLTAKQIQDMLGLTKPAMPMQQARPAQPQEHPFASSRFLQPVHKIDM 240 EGISKSYVFRGTKDLTAKQIQDMLGLTKPAMPMQQARPAQPQEHPFASSRFLQPVHKIDM Sbjct: 181 EGISKSYVFRGTKDLTAKQIQDMLGLTKPAMPMQQARPAQPQEHPFASSRFLQPVHKIDM 240 Query: 241 NLTDLLGELQRDPWPVTQGKRPLRSTGVALSIAVGLLEGTFPNTGARIMLFTGGPPTQGP 300 NLTDLLGELQRDPWPVTQGKRPLRSTGVALSIAVGLLEGTFPNTGARIMLFTGGPPTQGP Sbjct: 241 NLTDLLGELQRDPWPVTQGKRPLRSTGVALSIAVGLLEGTFPNTGARIMLFTGGPPTQGP 300 Query: 301 GMVVGDELKIPIRSWHDIEKDNARFMKKATKHYEMLANRTAANGHCIDIYACALDQTGLL 360 GMVVGDELKIPIRSWHDIEKDNARFMKKATKHYEMLANRTAANGHCIDIYACALDQTGLL Sbjct: 301 GMVVGDELKIPIRSWHDIEKDNARFMKKATKHYEMLANRTAANGHCIDIYACALDQTGLL 360 Query: 361 EMKCCANLTGGYMVMGDSFNTSLFKQTFQRIFTKDFNGDFRMAFGATLDVKTSRELKIAG 420 EMKCCANLTGGYMVMGDSFNTSLFKQTFQRIFTKDFNGDFRMAFGATLDVKTSRELKIAG Sbjct: 361 EMKCCANLTGGYMVMGDSFNTSLFKQTFQRIFTKDFNGDFRMAFGATLDVKTSRELKIAG 420 Query: 421 AIGPCVSLNVKGPCVSENELGVGGTSQWKICGLDPTSTLGIYFEVVNQHNTPIPQGGRGA 480 AIGPCVSLNVKGPCVSENELGVGGTSQWKICGLDPTSTLGIYFEVVNQHNTPIPQGGRGA Sbjct: 421 AIGPCVSLNVKGPCVSENELGVGGTSQWKICGLDPTSTLGIYFEVVNQHNTPIPQGGRGA 480 Query: 481 IQFVTHYQHSSTQRRIRVTTIARNWADVQSQLRHIEAAFDQEAAAVLMARLGVFRAESEE 540 IQFVTHYQHSSTQRRIRVTTIARNWADVQSQLRHIEAAFDQEAAAVLMARLGVFRAESEE Sbjct: 481 IQFVTHYQHSSTQRRIRVTTIARNWADVQSQLRHIEAAFDQEAAAVLMARLGVFRAESEE 540 Query: 541 GPDVLRWLDRQLIRLCQKFGQYNKEDPTSFRLSDSFSLYPQFMFHLRRSPFLQVFNNSPD 600 GPDVLRWLDRQLIRLCQKFGQYNKEDPTSFRLSDSFSLYPQFMFHLRRSPFLQVFNNSPD Sbjct: 541 GPDVLRWLDRQLIRLCQKFGQYNKEDPTSFRLSDSFSLYPQFMFHLRRSPFLQVFNNSPD 600 Query: 601 ESSYYRHHFARQDLTQSLIMIQPILYSYSFHGPPEPVLLDSSSILADRILLMDTFFQIVI 660 ESSYYRHHFARQDLTQSLIMIQPILYSYSFHGPPEPVLLDSSSILADRILLMDTFFQIVI Sbjct: 601 ESSYYRHHFARQDLTQSLIMIQPILYSYSFHGPPEPVLLDSSSILADRILLMDTFFQIVI 660 Query: 661 YLGETIAQWRKAGYQDMPEYENFKHLLQAPLDDAQEILQARFPMPRYINTEHGGSQARFL 720 YLGETIAQWRKAGYQDMPEYENFKHLLQAPLDDAQEILQARFPMPRYINTEHGGSQARFL Sbjct: 661 YLGETIAQWRKAGYQDMPEYENFKHLLQAPLDDAQEILQARFPMPRYINTEHGGSQARFL 720 Query: 721 LSKVNPSQTHNNLYAWGQETGAPILTDDVSLQVFMDHLKKLAVSSAC 767 LSKVNPSQTHNNLYAWGQETGAPILTDDVSLQVFMDHLKKLAVSSAC Sbjct: 721 LSKVNPSQTHNNLYAWGQETGAPILTDDVSLQVFMDHLKKLAVSSAC 767 >gi|14591928 Sec23 homolog B [Homo sapiens] Length = 767 Score = 1565 bits (4053), Expect = 0.0 Identities = 767/767 (100%), Positives = 767/767 (100%) Query: 1 MATYLEFIQQNEERDGVRFSWNVWPSSRLEATRMVVPLACLLTPLKERPDLPPVQYEPVL 60 MATYLEFIQQNEERDGVRFSWNVWPSSRLEATRMVVPLACLLTPLKERPDLPPVQYEPVL Sbjct: 1 MATYLEFIQQNEERDGVRFSWNVWPSSRLEATRMVVPLACLLTPLKERPDLPPVQYEPVL 60 Query: 61 CSRPTCKAVLNPLCQVDYRAKLWACNFCFQRNQFPPAYGGISEVNQPAELMPQFSTIEYV 120 CSRPTCKAVLNPLCQVDYRAKLWACNFCFQRNQFPPAYGGISEVNQPAELMPQFSTIEYV Sbjct: 61 CSRPTCKAVLNPLCQVDYRAKLWACNFCFQRNQFPPAYGGISEVNQPAELMPQFSTIEYV 120 Query: 121 IQRGAQSPLIFLYVVDTCLEEDDLQALKESLQMSLSLLPPDALVGLITFGRMVQVHELSC 180 IQRGAQSPLIFLYVVDTCLEEDDLQALKESLQMSLSLLPPDALVGLITFGRMVQVHELSC Sbjct: 121 IQRGAQSPLIFLYVVDTCLEEDDLQALKESLQMSLSLLPPDALVGLITFGRMVQVHELSC 180 Query: 181 EGISKSYVFRGTKDLTAKQIQDMLGLTKPAMPMQQARPAQPQEHPFASSRFLQPVHKIDM 240 EGISKSYVFRGTKDLTAKQIQDMLGLTKPAMPMQQARPAQPQEHPFASSRFLQPVHKIDM Sbjct: 181 EGISKSYVFRGTKDLTAKQIQDMLGLTKPAMPMQQARPAQPQEHPFASSRFLQPVHKIDM 240 Query: 241 NLTDLLGELQRDPWPVTQGKRPLRSTGVALSIAVGLLEGTFPNTGARIMLFTGGPPTQGP 300 NLTDLLGELQRDPWPVTQGKRPLRSTGVALSIAVGLLEGTFPNTGARIMLFTGGPPTQGP Sbjct: 241 NLTDLLGELQRDPWPVTQGKRPLRSTGVALSIAVGLLEGTFPNTGARIMLFTGGPPTQGP 300 Query: 301 GMVVGDELKIPIRSWHDIEKDNARFMKKATKHYEMLANRTAANGHCIDIYACALDQTGLL 360 GMVVGDELKIPIRSWHDIEKDNARFMKKATKHYEMLANRTAANGHCIDIYACALDQTGLL Sbjct: 301 GMVVGDELKIPIRSWHDIEKDNARFMKKATKHYEMLANRTAANGHCIDIYACALDQTGLL 360 Query: 361 EMKCCANLTGGYMVMGDSFNTSLFKQTFQRIFTKDFNGDFRMAFGATLDVKTSRELKIAG 420 EMKCCANLTGGYMVMGDSFNTSLFKQTFQRIFTKDFNGDFRMAFGATLDVKTSRELKIAG Sbjct: 361 EMKCCANLTGGYMVMGDSFNTSLFKQTFQRIFTKDFNGDFRMAFGATLDVKTSRELKIAG 420 Query: 421 AIGPCVSLNVKGPCVSENELGVGGTSQWKICGLDPTSTLGIYFEVVNQHNTPIPQGGRGA 480 AIGPCVSLNVKGPCVSENELGVGGTSQWKICGLDPTSTLGIYFEVVNQHNTPIPQGGRGA Sbjct: 421 AIGPCVSLNVKGPCVSENELGVGGTSQWKICGLDPTSTLGIYFEVVNQHNTPIPQGGRGA 480 Query: 481 IQFVTHYQHSSTQRRIRVTTIARNWADVQSQLRHIEAAFDQEAAAVLMARLGVFRAESEE 540 IQFVTHYQHSSTQRRIRVTTIARNWADVQSQLRHIEAAFDQEAAAVLMARLGVFRAESEE Sbjct: 481 IQFVTHYQHSSTQRRIRVTTIARNWADVQSQLRHIEAAFDQEAAAVLMARLGVFRAESEE 540 Query: 541 GPDVLRWLDRQLIRLCQKFGQYNKEDPTSFRLSDSFSLYPQFMFHLRRSPFLQVFNNSPD 600 GPDVLRWLDRQLIRLCQKFGQYNKEDPTSFRLSDSFSLYPQFMFHLRRSPFLQVFNNSPD Sbjct: 541 GPDVLRWLDRQLIRLCQKFGQYNKEDPTSFRLSDSFSLYPQFMFHLRRSPFLQVFNNSPD 600 Query: 601 ESSYYRHHFARQDLTQSLIMIQPILYSYSFHGPPEPVLLDSSSILADRILLMDTFFQIVI 660 ESSYYRHHFARQDLTQSLIMIQPILYSYSFHGPPEPVLLDSSSILADRILLMDTFFQIVI Sbjct: 601 ESSYYRHHFARQDLTQSLIMIQPILYSYSFHGPPEPVLLDSSSILADRILLMDTFFQIVI 660 Query: 661 YLGETIAQWRKAGYQDMPEYENFKHLLQAPLDDAQEILQARFPMPRYINTEHGGSQARFL 720 YLGETIAQWRKAGYQDMPEYENFKHLLQAPLDDAQEILQARFPMPRYINTEHGGSQARFL Sbjct: 661 YLGETIAQWRKAGYQDMPEYENFKHLLQAPLDDAQEILQARFPMPRYINTEHGGSQARFL 720 Query: 721 LSKVNPSQTHNNLYAWGQETGAPILTDDVSLQVFMDHLKKLAVSSAC 767 LSKVNPSQTHNNLYAWGQETGAPILTDDVSLQVFMDHLKKLAVSSAC Sbjct: 721 LSKVNPSQTHNNLYAWGQETGAPILTDDVSLQVFMDHLKKLAVSSAC 767 >gi|38202214 SEC23-related protein A [Homo sapiens] Length = 765 Score = 1353 bits (3502), Expect = 0.0 Identities = 649/766 (84%), Positives = 710/766 (92%), Gaps = 2/766 (0%) Query: 1 MATYLEFIQQNEERDGVRFSWNVWPSSRLEATRMVVPLACLLTPLKERPDLPPVQYEPVL 60 M TYLEFIQQNEERDGVRFSWNVWPSSRLEATRMVVP+A L TPLKERPDLPP+QYEPVL Sbjct: 1 MTTYLEFIQQNEERDGVRFSWNVWPSSRLEATRMVVPVAALFTPLKERPDLPPIQYEPVL 60 Query: 61 CSRPTCKAVLNPLCQVDYRAKLWACNFCFQRNQFPPAYGGISEVNQPAELMPQFSTIEYV 120 CSR TC+AVLNPLCQVDYRAKLWACNFC+QRNQFPP+Y GISE+NQPAEL+PQFS+IEYV Sbjct: 61 CSRTTCRAVLNPLCQVDYRAKLWACNFCYQRNQFPPSYAGISELNQPAELLPQFSSIEYV 120 Query: 121 IQRGAQSPLIFLYVVDTCLEEDDLQALKESLQMSLSLLPPDALVGLITFGRMVQVHELSC 180 + RG Q PLIFLYVVDTC+E++DLQALKES+QMSLSLLPP ALVGLITFGRMVQVHEL C Sbjct: 121 VLRGPQMPLIFLYVVDTCMEDEDLQALKESMQMSLSLLPPTALVGLITFGRMVQVHELGC 180 Query: 181 EGISKSYVFRGTKDLTAKQIQDMLGLTKPAMPMQQARPAQPQEHPFASSRFLQPVHKIDM 240 EGISKSYVFRGTKDL+AKQ+Q+MLGL+K +P+ QA + P S+RFLQPV KIDM Sbjct: 181 EGISKSYVFRGTKDLSAKQLQEMLGLSK--VPLTQATRGPQVQQPPPSNRFLQPVQKIDM 238 Query: 241 NLTDLLGELQRDPWPVTQGKRPLRSTGVALSIAVGLLEGTFPNTGARIMLFTGGPPTQGP 300 NLTDLLGELQRDPWPV QGKRPLRS+GVALSIAVGLLE TFPNTGARIM+F GGP TQGP Sbjct: 239 NLTDLLGELQRDPWPVPQGKRPLRSSGVALSIAVGLLECTFPNTGARIMMFIGGPATQGP 298 Query: 301 GMVVGDELKIPIRSWHDIEKDNARFMKKATKHYEMLANRTAANGHCIDIYACALDQTGLL 360 GMVVGDELK PIRSWHDI+KDNA+++KK TKH+E LANR A GH IDIYACALDQTGLL Sbjct: 299 GMVVGDELKTPIRSWHDIDKDNAKYVKKGTKHFEALANRAATTGHVIDIYACALDQTGLL 358 Query: 361 EMKCCANLTGGYMVMGDSFNTSLFKQTFQRIFTKDFNGDFRMAFGATLDVKTSRELKIAG 420 EMKCC NLTGGYMVMGDSFNTSLFKQTFQR+FTKD +G F+M FG TL++KTSRE+KI+G Sbjct: 359 EMKCCPNLTGGYMVMGDSFNTSLFKQTFQRVFTKDMHGQFKMGFGGTLEIKTSREIKISG 418 Query: 421 AIGPCVSLNVKGPCVSENELGVGGTSQWKICGLDPTSTLGIYFEVVNQHNTPIPQGGRGA 480 AIGPCVSLN KGPCVSENE+G GGT QWKICGL PT+TL IYFEVVNQHN PIPQGGRGA Sbjct: 419 AIGPCVSLNSKGPCVSENEIGTGGTCQWKICGLSPTTTLAIYFEVVNQHNAPIPQGGRGA 478 Query: 481 IQFVTHYQHSSTQRRIRVTTIARNWADVQSQLRHIEAAFDQEAAAVLMARLGVFRAESEE 540 IQFVT YQHSS QRRIRVTTIARNWAD Q+Q+++I A+FDQEAAA+LMARL ++RAE+EE Sbjct: 479 IQFVTQYQHSSGQRRIRVTTIARNWADAQTQIQNIAASFDQEAAAILMARLAIYRAETEE 538 Query: 541 GPDVLRWLDRQLIRLCQKFGQYNKEDPTSFRLSDSFSLYPQFMFHLRRSPFLQVFNNSPD 600 GPDVLRWLDRQLIRLCQKFG+Y+K+DP+SFR S++FSLYPQFMFHLRRS FLQVFNNSPD Sbjct: 539 GPDVLRWLDRQLIRLCQKFGEYHKDDPSSFRFSETFSLYPQFMFHLRRSSFLQVFNNSPD 598 Query: 601 ESSYYRHHFARQDLTQSLIMIQPILYSYSFHGPPEPVLLDSSSILADRILLMDTFFQIVI 660 ESSYYRHHF RQDLTQSLIMIQPILY+YSF GPPEPVLLDSSSILADRILLMDTFFQI+I Sbjct: 599 ESSYYRHHFMRQDLTQSLIMIQPILYAYSFSGPPEPVLLDSSSILADRILLMDTFFQILI 658 Query: 661 YLGETIAQWRKAGYQDMPEYENFKHLLQAPLDDAQEILQARFPMPRYINTEHGGSQARFL 720 Y GETIAQWRK+GYQDMPEYENF+HLLQAP+DDAQEIL +RFPMPRYI+TEHGGSQARFL Sbjct: 659 YHGETIAQWRKSGYQDMPEYENFRHLLQAPVDDAQEILHSRFPMPRYIDTEHGGSQARFL 718 Query: 721 LSKVNPSQTHNNLYAWGQETGAPILTDDVSLQVFMDHLKKLAVSSA 766 LSKVNPSQTHNN+YAWGQE+GAPILTDDVSLQVFMDHLKKLAVSSA Sbjct: 719 LSKVNPSQTHNNMYAWGQESGAPILTDDVSLQVFMDHLKKLAVSSA 764 >gi|112382214 SEC24 (S. cerevisiae) homolog B isoform b [Homo sapiens] Length = 1233 Score = 83.2 bits (204), Expect = 8e-16 Identities = 132/637 (20%), Positives = 239/637 (37%), Gaps = 97/637 (15%) Query: 15 DGVRFSWNVWPSSRLEATRMVVPLACLLTPLKERPDLPPVQYEPVLCSRPTCKAVLNPLC 74 D R + P ++ + +PL LL P ++ LP + ++ R +C+ +NP Sbjct: 523 DSFRCTLTNIPQTQALLNKAKLPLGLLLHPFRDLTQLPVITSNTIVRCR-SCRTYINPFV 581 Query: 75 Q-VDYRAKLWACNFCFQRNQFP------PAYGGISEVNQPAELMPQFSTIEYVIQRG--- 124 +D R W CN C++ N P P E ++ E+ Q ST+E++ Sbjct: 582 SFIDQRR--WKCNLCYRVNDVPEEFMYNPLTRSYGEPHKRPEV--QNSTVEFIASSDYML 637 Query: 125 -AQSPLIFLYVVD---TCLEEDDLQALKESLQMSLSLLPPDA--LVGLITFGRMVQVHEL 178 P ++L+V+D +E L L +SL +L LP D+ +G +TF + + L Sbjct: 638 RPPQPAVYLFVLDVSHNAVEAGYLTILCQSLLENLDKLPGDSRTRIGFMTFDSTIHFYNL 697 Query: 179 SCEGISKSYVFRGTKDLTAKQIQDMLGLTKPAMPMQQARPAQPQEHPFASSRFLQPVHKI 238 EG+S+ + L I D+ T ++ L +++ Sbjct: 698 Q-EGLSQPQM------LIVSDIDDVFLPTPDSL--------------------LVNLYES 730 Query: 239 DMNLTDLLGELQRDPWPVTQGKRPLRSTGVALSIAVGLLEGTFPNTGARIMLFTGGPPTQ 298 + DLL L P T + + G AL A L+ TG R+ +F P+ Sbjct: 731 KELIKDLLNAL---PNMFTNTRETHSALGPALQAAFKLMS----PTGGRVSVFQTQLPSL 783 Query: 299 GPGMVVGDELKIPIRSWHDIEKDNARFMKKATKHYEMLANRTAANGHCIDIYACALDQTG 358 G G++ E S ++ + AT Y+ LA + +D++ + + Sbjct: 784 GAGLLQSREDPNQRSSTKVVQ-----HLGPATDFYKKLALDCSGQQTAVDLFLLSSQYSD 838 Query: 359 LLEMKCCANLTGGYMVMGDSFN-------TSLFKQTFQRIFTKDFNGDFRMAFGATLDVK 411 L + C + + G + SF+ ++ +R T+ ++ F A + ++ Sbjct: 839 LASLACMSKYSAGCIYYYPSFHYTHNPSQAEKLQKDLKRYLTR------KIGFEAVMRIR 892 Query: 412 TSRELKIAGAIGPCVSLNVKGPCVSENELGVGGTSQWKICGLDPTSTLGIYFEVVNQHNT 471 ++ L + G V T + ++P + + + Sbjct: 893 CTKGLSMHTFHG---------------NFFVRSTDLLSLANINPDAGFAVQLSI----EE 933 Query: 472 PIPQGGRGAIQFVTHYQHSSTQRRIRVTTIARNWADVQSQLRHIEAAFDQEAAAVLMARL 531 + Q Y S +RRIRV T+ V S L + A D +AA L+A + Sbjct: 934 SLTDTSLVCFQTALLYTSSKGERRIRVHTLC---LPVVSSLADVYAGVDVQAAICLLANM 990 Query: 532 GVFRAESEEGPDVLRWLDRQLIRLCQKFGQ-YNKEDPTSFRLSDSFSLYPQFMFH-LRRS 589 V R+ S D L ++ +G + ++ S L+P ++ L++ Sbjct: 991 AVDRSVSSSLSDARDALVNAVVDSLSAYGSTVSNLQHSALMAPSSLKLFPLYVLALLKQK 1050 Query: 590 PFLQVFNNSPDESSYYRHHFARQDLTQSLIMIQPILY 626 F + D+ Y Q L + MI P LY Sbjct: 1051 AFRTGTSTRLDDRVYAMCQIKSQPLVHLMKMIHPNLY 1087 >gi|112382212 SEC24 (S. cerevisiae) homolog B isoform a [Homo sapiens] Length = 1268 Score = 83.2 bits (204), Expect = 8e-16 Identities = 132/637 (20%), Positives = 239/637 (37%), Gaps = 97/637 (15%) Query: 15 DGVRFSWNVWPSSRLEATRMVVPLACLLTPLKERPDLPPVQYEPVLCSRPTCKAVLNPLC 74 D R + P ++ + +PL LL P ++ LP + ++ R +C+ +NP Sbjct: 558 DSFRCTLTNIPQTQALLNKAKLPLGLLLHPFRDLTQLPVITSNTIVRCR-SCRTYINPFV 616 Query: 75 Q-VDYRAKLWACNFCFQRNQFP------PAYGGISEVNQPAELMPQFSTIEYVIQRG--- 124 +D R W CN C++ N P P E ++ E+ Q ST+E++ Sbjct: 617 SFIDQRR--WKCNLCYRVNDVPEEFMYNPLTRSYGEPHKRPEV--QNSTVEFIASSDYML 672 Query: 125 -AQSPLIFLYVVD---TCLEEDDLQALKESLQMSLSLLPPDA--LVGLITFGRMVQVHEL 178 P ++L+V+D +E L L +SL +L LP D+ +G +TF + + L Sbjct: 673 RPPQPAVYLFVLDVSHNAVEAGYLTILCQSLLENLDKLPGDSRTRIGFMTFDSTIHFYNL 732 Query: 179 SCEGISKSYVFRGTKDLTAKQIQDMLGLTKPAMPMQQARPAQPQEHPFASSRFLQPVHKI 238 EG+S+ + L I D+ T ++ L +++ Sbjct: 733 Q-EGLSQPQM------LIVSDIDDVFLPTPDSL--------------------LVNLYES 765 Query: 239 DMNLTDLLGELQRDPWPVTQGKRPLRSTGVALSIAVGLLEGTFPNTGARIMLFTGGPPTQ 298 + DLL L P T + + G AL A L+ TG R+ +F P+ Sbjct: 766 KELIKDLLNAL---PNMFTNTRETHSALGPALQAAFKLMS----PTGGRVSVFQTQLPSL 818 Query: 299 GPGMVVGDELKIPIRSWHDIEKDNARFMKKATKHYEMLANRTAANGHCIDIYACALDQTG 358 G G++ E S ++ + AT Y+ LA + +D++ + + Sbjct: 819 GAGLLQSREDPNQRSSTKVVQ-----HLGPATDFYKKLALDCSGQQTAVDLFLLSSQYSD 873 Query: 359 LLEMKCCANLTGGYMVMGDSFN-------TSLFKQTFQRIFTKDFNGDFRMAFGATLDVK 411 L + C + + G + SF+ ++ +R T+ ++ F A + ++ Sbjct: 874 LASLACMSKYSAGCIYYYPSFHYTHNPSQAEKLQKDLKRYLTR------KIGFEAVMRIR 927 Query: 412 TSRELKIAGAIGPCVSLNVKGPCVSENELGVGGTSQWKICGLDPTSTLGIYFEVVNQHNT 471 ++ L + G V T + ++P + + + Sbjct: 928 CTKGLSMHTFHG---------------NFFVRSTDLLSLANINPDAGFAVQLSI----EE 968 Query: 472 PIPQGGRGAIQFVTHYQHSSTQRRIRVTTIARNWADVQSQLRHIEAAFDQEAAAVLMARL 531 + Q Y S +RRIRV T+ V S L + A D +AA L+A + Sbjct: 969 SLTDTSLVCFQTALLYTSSKGERRIRVHTLC---LPVVSSLADVYAGVDVQAAICLLANM 1025 Query: 532 GVFRAESEEGPDVLRWLDRQLIRLCQKFGQ-YNKEDPTSFRLSDSFSLYPQFMFH-LRRS 589 V R+ S D L ++ +G + ++ S L+P ++ L++ Sbjct: 1026 AVDRSVSSSLSDARDALVNAVVDSLSAYGSTVSNLQHSALMAPSSLKLFPLYVLALLKQK 1085 Query: 590 PFLQVFNNSPDESSYYRHHFARQDLTQSLIMIQPILY 626 F + D+ Y Q L + MI P LY Sbjct: 1086 AFRTGTSTRLDDRVYAMCQIKSQPLVHLMKMIHPNLY 1122 >gi|116174780 SEC24 related gene family, member A [Homo sapiens] Length = 1093 Score = 75.1 bits (183), Expect = 2e-13 Identities = 147/681 (21%), Positives = 255/681 (37%), Gaps = 109/681 (16%) Query: 25 PSSRLEATRMVVPLACLLTPLKERPDLPPVQYEPVLCSRPTCKAVLNPLCQ-VDYRAKLW 83 P ++ + +PL LL P K+ LP V ++ R +C+ +NP +D R W Sbjct: 394 PQTQALLNKAKLPLGLLLHPFKDLVQLPVVTSSTIVRCR-SCRTYINPFVSFLDQRR--W 450 Query: 84 ACNFCFQRNQFPP--AYGGISEVNQPAELMP--QFSTIEYV-----IQRGAQSPLIFLYV 134 CN C++ N P Y ++ V P Q +TIE++ + R Q P ++L+V Sbjct: 451 KCNLCYRVNDVPEEFLYNPLTRVYGEPHRRPEVQNATIEFMAPSEYMLRPPQPP-VYLFV 509 Query: 135 VD---TCLEEDDLQALKESLQMSLSLLPPD--ALVGLITFGRMVQVHELSCEGISKSYVF 189 D +E L ++ +SL +L LLP + +G ITF + + L E +S+ + Sbjct: 510 FDVSHNAVETGYLNSVCQSLLDNLDLLPGNTRTKIGFITFDSTIHFYGLQ-ESLSQPQM- 567 Query: 190 RGTKDLTAKQIQDMLGLTKPAMPMQQARPAQPQEHPFASSRFLQPVHKIDMNLTDLLGEL 249 L I+D+ +PM + L +++ + DLL L Sbjct: 568 -----LIVSDIEDVF------IPMPE--------------NLLVNLNESKELVQDLLKTL 602 Query: 250 QRDPWPVTQGKRPLRSTGVALSIAVGLLEGTFPNTGARIMLFTGGPPTQGPGMVVGDELK 309 P T+ + G AL A L+ TG R+ +F PT G G + E Sbjct: 603 ---PQMFTKTLETQSALGPALQAAFKLMS----PTGGRMSVFQTQLPTLGVGALKPREEP 655 Query: 310 IPIRSWHDIEKDNARFMKKATKHYEMLANRTAANGHCIDIYACALDQTGLLEMKCCANLT 369 S DI M +T Y+ LA + +D++ + + L + C + + Sbjct: 656 NHRSSAKDIH------MTPSTDFYKKLALDCSGQQVAVDLFLLSGQYSDLASLGCISRYS 709 Query: 370 GGYMVMGDSFN-------TSLFKQTFQRIFTKDFNGDFRMAFGATLDVKTSRELKIAGAI 422 G + S++ ++ QR T+ ++ F A + ++ ++ L I Sbjct: 710 AGSVYYYPSYHHQHNPVQVQKLQKELQRYLTR------KIGFEAVMRIRCTKGLSIHTFH 763 Query: 423 GPCVSLNVKGPCVSENELGVGGTSQWKICGLDPTSTLGIYFEVVNQHNTPIPQGGRGAIQ 482 G V T + ++P + + V + + Q Sbjct: 764 G---------------NFFVRSTDLLSLPNVNPDAGYAVQMSV----EESLTDTQLVSFQ 804 Query: 483 FVTHYQHSSTQRRIRVTTIARNWADVQSQLRHIEAAFDQEAAAVLMARLGVFRAESEEGP 542 Y S +RRIRV T+ V S L + D +A + L+A + V R+ + Sbjct: 805 SALLYTSSKGERRIRVHTLC---LPVVSTLNDVFLGADVQAISGLLANMAVDRSMTASLS 861 Query: 543 DVLRWLDRQLIRLCQKF-GQYNKEDPTSFRLSDSFSLYPQFMFHLRRSPFLQVFNNSP-D 600 D L +I + + S L+P F+ L + Q N+ D Sbjct: 862 DARDALVNAVIDSLSAYRSSVLSNQQPGLMVPFSLRLFPLFVLALLKQKSFQTGTNARLD 921 Query: 601 ESSYYRHHFARQDLTQSLIMIQPILY-----------SYSFHGPPEPVLLDSS--SILAD 647 E + Q L ++ P LY + S P+P +L S + D Sbjct: 922 ERIFAMCQVKNQPLVYLMLTTHPSLYRVDNLSDEGALNISDRTIPQPPILQLSVEKLSRD 981 Query: 648 RILLMDTFFQIVIYLGETIAQ 668 LMD +++++G+ Q Sbjct: 982 GAFLMDAGSVLMLWVGKNCTQ 1002 >gi|38373671 SEC24-related protein C [Homo sapiens] Length = 1094 Score = 73.6 bits (179), Expect = 7e-13 Identities = 138/692 (19%), Positives = 260/692 (37%), Gaps = 113/692 (16%) Query: 20 SWNVWPSSRLEATRMVVPLACLLTPLKERPDLPPVQYE-------PVLCSRPTCKAVLNP 72 S+N+ P + A + VPLA ++ PL P Y P+ C+R CKA + P Sbjct: 378 SYNI-PCTSDMAKQAQVPLAAVIKPLARLPPEEASPYVVDHGESGPLRCNR--CKAYMCP 434 Query: 73 LCQVDYRAKLWACNFCFQRNQFPPAY--------GGISEVNQPAELMPQF---STIEYVI 121 Q + + C FC N PP Y + ++P + + +T++Y Sbjct: 435 FMQFIEGGRRFQCCFCSCINDVPPQYFQHLDHTGKRVDAYDRPELSLGSYEFLATVDYCK 494 Query: 122 QRGAQSPLIFLYVVDT---CLEEDDLQALKESLQMSLSLLPPDA-------LVGLITFGR 171 SP F++++D + ++ L E L+ L LP + VG +T+ + Sbjct: 495 NNKFPSPPAFIFMIDVSYNAIRTGLVRLLCEELKSLLDFLPREGGAEESAIRVGFVTYNK 554 Query: 172 MVQVHELSCEGISKSYVFRGTKDLTAKQIQDMLGLTKPAMPMQQARPAQPQEHPFASSRF 231 ++ + + L Q+ + + +P+ F Sbjct: 555 VLHFYNVK-------------SSLAQPQMMVVSDVADMFVPLLDG--------------F 587 Query: 232 LQPVHKIDMNLTDLLGELQRDPWPVTQGKRPLRSTGVALSIAVGLLEGTFPNTGARIMLF 291 L V++ +T LL ++ + R + V + I G+ ++ LF Sbjct: 588 LVNVNESRAVITSLLDQIPE----MFADTRETETVFVPV-IQAGMEALKAAECAGKLFLF 642 Query: 292 -TGGPPTQGPGMVVGDELKIPIRSWHDIEKDNARFMKKATKHYEMLANRTAANGHCIDIY 350 T P + PG + + + I + +K+ F + T Y+ LA A G C+D++ Sbjct: 643 HTSLPIAEAPGKLKNRDDRKLINT----DKEKTLFQPQ-TGAYQTLAKECVAQGCCVDLF 697 Query: 351 ACALDQTGLLEMKCCANLTGGYMVMGDSFNTSLFKQTFQRIFTKDFNGDFR--MAFGATL 408 + + LTGG + SF + Q F D D + + F A + Sbjct: 698 LFPNQYVDVATLSVVPQLTGGSVYKYASFQV----ENDQERFLSDLRRDVQKVVGFDAVM 753 Query: 409 DVKTSRELKIAGAIGPCVSLNVKGPCVSENELGVGGTSQWKICGLDPTSTLGIYFEVVNQ 468 V+TS ++ G N T+ ++ GLD T+ + F + Sbjct: 754 RVRTSTGIRAVDFFGAFYMSN---------------TTDVELAGLDGDKTVTVEF----K 794 Query: 469 HNTPIPQGGRGAIQFVTHYQHSSTQRRIRVTTIARNWADVQSQLRHIEAAFDQEAAAVLM 528 H+ + + +Q Y + QRR+R+ +A N +QL + + + M Sbjct: 795 HDDRLNEESGALLQCALLYTSCAGQRRLRIHNLALNCC---TQLADLYRNCETDTLINYM 851 Query: 529 ARL---GVFRAESEEGPDVLRWLDRQLIRLCQKFGQYNKEDPTS---FRLSDSFSLYPQF 582 A+ GV + + D L Q++ +K N P+S L + L P + Sbjct: 852 AKFAYRGVLNSPVKAVRDTLITQCAQILACYRK----NCASPSSAGQLILPECMKLLPVY 907 Query: 583 MFHLRRSPFLQV-FNNSPDESSYYRHHFARQDLTQSLIMIQPILYSYS---FHGPPEPVL 638 + + +S LQ + D+ +Y R D+T++ + P L + EP Sbjct: 908 LNCVLKSDVLQPGAEVTTDDRAYVRQLVTSMDVTETNVFFYPRLLPLTKSPVESTTEPPA 967 Query: 639 LDSSS--ILADRILLMDTFFQIVIYLGETIAQ 668 + +S + I L++ + +++G ++ Q Sbjct: 968 VRASEERLSNGDIYLLENGLNLFLWVGASVQQ 999 >gi|38373669 SEC24-related protein C [Homo sapiens] Length = 1094 Score = 73.6 bits (179), Expect = 7e-13 Identities = 138/692 (19%), Positives = 260/692 (37%), Gaps = 113/692 (16%) Query: 20 SWNVWPSSRLEATRMVVPLACLLTPLKERPDLPPVQYE-------PVLCSRPTCKAVLNP 72 S+N+ P + A + VPLA ++ PL P Y P+ C+R CKA + P Sbjct: 378 SYNI-PCTSDMAKQAQVPLAAVIKPLARLPPEEASPYVVDHGESGPLRCNR--CKAYMCP 434 Query: 73 LCQVDYRAKLWACNFCFQRNQFPPAY--------GGISEVNQPAELMPQF---STIEYVI 121 Q + + C FC N PP Y + ++P + + +T++Y Sbjct: 435 FMQFIEGGRRFQCCFCSCINDVPPQYFQHLDHTGKRVDAYDRPELSLGSYEFLATVDYCK 494 Query: 122 QRGAQSPLIFLYVVDT---CLEEDDLQALKESLQMSLSLLPPDA-------LVGLITFGR 171 SP F++++D + ++ L E L+ L LP + VG +T+ + Sbjct: 495 NNKFPSPPAFIFMIDVSYNAIRTGLVRLLCEELKSLLDFLPREGGAEESAIRVGFVTYNK 554 Query: 172 MVQVHELSCEGISKSYVFRGTKDLTAKQIQDMLGLTKPAMPMQQARPAQPQEHPFASSRF 231 ++ + + L Q+ + + +P+ F Sbjct: 555 VLHFYNVK-------------SSLAQPQMMVVSDVADMFVPLLDG--------------F 587 Query: 232 LQPVHKIDMNLTDLLGELQRDPWPVTQGKRPLRSTGVALSIAVGLLEGTFPNTGARIMLF 291 L V++ +T LL ++ + R + V + I G+ ++ LF Sbjct: 588 LVNVNESRAVITSLLDQIPE----MFADTRETETVFVPV-IQAGMEALKAAECAGKLFLF 642 Query: 292 -TGGPPTQGPGMVVGDELKIPIRSWHDIEKDNARFMKKATKHYEMLANRTAANGHCIDIY 350 T P + PG + + + I + +K+ F + T Y+ LA A G C+D++ Sbjct: 643 HTSLPIAEAPGKLKNRDDRKLINT----DKEKTLFQPQ-TGAYQTLAKECVAQGCCVDLF 697 Query: 351 ACALDQTGLLEMKCCANLTGGYMVMGDSFNTSLFKQTFQRIFTKDFNGDFR--MAFGATL 408 + + LTGG + SF + Q F D D + + F A + Sbjct: 698 LFPNQYVDVATLSVVPQLTGGSVYKYASFQV----ENDQERFLSDLRRDVQKVVGFDAVM 753 Query: 409 DVKTSRELKIAGAIGPCVSLNVKGPCVSENELGVGGTSQWKICGLDPTSTLGIYFEVVNQ 468 V+TS ++ G N T+ ++ GLD T+ + F + Sbjct: 754 RVRTSTGIRAVDFFGAFYMSN---------------TTDVELAGLDGDKTVTVEF----K 794 Query: 469 HNTPIPQGGRGAIQFVTHYQHSSTQRRIRVTTIARNWADVQSQLRHIEAAFDQEAAAVLM 528 H+ + + +Q Y + QRR+R+ +A N +QL + + + M Sbjct: 795 HDDRLNEESGALLQCALLYTSCAGQRRLRIHNLALNCC---TQLADLYRNCETDTLINYM 851 Query: 529 ARL---GVFRAESEEGPDVLRWLDRQLIRLCQKFGQYNKEDPTS---FRLSDSFSLYPQF 582 A+ GV + + D L Q++ +K N P+S L + L P + Sbjct: 852 AKFAYRGVLNSPVKAVRDTLITQCAQILACYRK----NCASPSSAGQLILPECMKLLPVY 907 Query: 583 MFHLRRSPFLQV-FNNSPDESSYYRHHFARQDLTQSLIMIQPILYSYS---FHGPPEPVL 638 + + +S LQ + D+ +Y R D+T++ + P L + EP Sbjct: 908 LNCVLKSDVLQPGAEVTTDDRAYVRQLVTSMDVTETNVFFYPRLLPLTKSPVESTTEPPA 967 Query: 639 LDSSS--ILADRILLMDTFFQIVIYLGETIAQ 668 + +S + I L++ + +++G ++ Q Sbjct: 968 VRASEERLSNGDIYLLENGLNLFLWVGASVQQ 999 >gi|190343021 Sec24-related protein D [Homo sapiens] Length = 1032 Score = 63.9 bits (154), Expect = 5e-10 Identities = 121/650 (18%), Positives = 235/650 (36%), Gaps = 97/650 (14%) Query: 9 QQNEERDGVRFSWNVWPSSRLEATRMVVPLACLLTPLKERPDLPPVQY-------EPVLC 61 Q N +R + +P + A + +PLA ++ P P Y PV C Sbjct: 304 QGNASPRFIRCTTYCFPCTSDMAKQAQIPLAAVIKPFATIPSNESPLYLVNHGESGPVRC 363 Query: 62 SRPTCKAVLNPLCQVDYRAKLWACNFCFQRNQFPPAY--------GGISEVNQPAELMPQ 113 +R CKA + P Q + + C FC N PP Y + +P + Sbjct: 364 NR--CKAYMCPFMQFIEGGRRYQCGFCNCVNDVPPFYFQHLDHIGRRLDHYEKPELSLGS 421 Query: 114 F---STIEYVIQRGAQSPLIFLYVVDTC---LEEDDLQALKESLQMSLSLLPPDAL---- 163 + +T++Y + +P F++++D ++ ++ + E L+ L +P + Sbjct: 422 YEYVATLDYCRKSKPPNPPAFIFMIDVSYSNIKNGLVKLICEELKTMLEKIPKEEQEETS 481 Query: 164 ---VGLITFGRMVQVHELSCEGISKSYVFRGTKDLTAKQIQDMLGLTKPAMPMQQARPAQ 220 VG IT+ +++ + F +L Q+ + + + +P+ Sbjct: 482 AIRVGFITYNKVL-------------HFFNVKSNLAQPQMMVVTDVGEVFVPLLDGFLVN 528 Query: 221 PQEHPFASSRFLQPVHKIDMNLTDLLGELQRDPWPVTQGKRPLRSTGVALSIAVGLLEGT 280 QE +H + + D+ + + T A I G+ Sbjct: 529 YQESQSV-------IHNLLDQIPDMFADSNEN------------ETVFAPVIQAGMEALK 569 Query: 281 FPNTGARIMLFTGGPPT-QGPGMVVGDELKIPIRSWHDIEKDNARFMKKATKHYEMLANR 339 + ++ +F PT + PG + + K + + +K+ F + T Y+ LA Sbjct: 570 AADCPGKLFIFHSSLPTAEAPGKLKNRDDKKLVNT----DKEKILFQPQ-TNVYDSLAKD 624 Query: 340 TAANGHCIDIYACALDQTGLLEMKCCANLTGGYMVMGDSFNTSLFKQTFQRIFTKDFNGD 399 A+G + ++ + + LTGG + ++F L +Q F D + Sbjct: 625 CVAHGCSVTLFLFPSQYVDVASLGLVPQLTGGTLYKYNNFQMHLDRQQFLNDLRNDI--E 682 Query: 400 FRMAFGATLDVKTSRELKIAGAIGPCVSLNVKGPCVSENELGVGGTSQWKICGLDPTSTL 459 ++ F A + V+TS + G + N T+ ++ +D + Sbjct: 683 KKIGFDAIMRVRTSTGFRATDFFGGILMNN---------------TTDVEMAAIDCDKAV 727 Query: 460 GIYFEVVNQHNTPIPQGGRGAIQFVTHYQHSSTQRRIRVTTIARNWADVQSQLRHIEAAF 519 + F +H+ + + IQ Y S QRR+R+ + N SQL + + Sbjct: 728 TVEF----KHDDKLSEDSGALIQCAVLYTTISGQRRLRIHNLGLN---CSSQLADLYKSC 780 Query: 520 DQEAAAVLMARLGVFRAESEEGPDVLRWL---DRQLIRLCQKFGQYNKEDPTSFRLSDSF 576 + +A A+ F+A + V+R + + C + + + L DS Sbjct: 781 ETDALINFFAK-SAFKAVLHQPLKVIREILVNQTAHMLACYRKNCASPSAASQLILPDSM 839 Query: 577 SLYPQFM-FHLRRSPFLQVFNNSPDESSYYRHHFARQDLTQSLIMIQPIL 625 + P +M L+ L S DE +Y R + S + P L Sbjct: 840 KVLPVYMNCLLKNCVLLSRPEISTDERAYQRQLVMTMGVADSQLFFYPQL 889 >gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens] Length = 4374 Score = 31.6 bits (70), Expect = 2.9 Identities = 28/105 (26%), Positives = 45/105 (42%), Gaps = 9/105 (8%) Query: 651 LMDTFFQIVIYLGETIAQWRKAGYQDMPEYENFKHLLQAPLDDAQEILQARFPMPRYINT 710 L+D F I+ G+T+ D PE E K LL A L+ +++ F Y + Sbjct: 57 LLDRFDGILADAGQTVENMSWMLVCDRPEREQLKMLLLAVLNFTALLIEYSFSRHLYSSI 116 Query: 711 EH-----GGSQARFLLSKVNP----SQTHNNLYAWGQETGAPILT 746 EH S + +L+ +N S+ N + G + P+LT Sbjct: 117 EHLTTLLASSDMQVVLAVLNLLYVFSKRSNYITRLGSDKRTPLLT 161 >gi|166362728 epidermal growth factor (beta-urogastrone) [Homo sapiens] Length = 1207 Score = 30.4 bits (67), Expect = 6.5 Identities = 13/31 (41%), Positives = 15/31 (48%) Query: 345 HCIDIYACALDQTGLLEMKCCANLTGGYMVM 375 HC+DI C L + E C N GGY M Sbjct: 909 HCLDIDECQLGEHSCGENASCTNTEGGYTCM 939 >gi|222352129 von Willebrand factor A domain containing 5B2 [Homo sapiens] Length = 1242 Score = 30.0 bits (66), Expect = 8.4 Identities = 19/64 (29%), Positives = 29/64 (45%), Gaps = 12/64 (18%) Query: 146 ALKESLQMSLSLLPPDALVGLITFGRMVQ------------VHELSCEGISKSYVFRGTK 193 A K+++ +++ LPP L+ L FG +VQ +L CE I V G Sbjct: 365 AHKDAIVLAVKSLPPQTLINLAVFGTLVQPLFPESRPCSDDAVQLICESIETLQVPSGPP 424 Query: 194 DLTA 197 D+ A Sbjct: 425 DVLA 428 >gi|4503963 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme isoform B [Homo sapiens] Length = 400 Score = 30.0 bits (66), Expect = 8.4 Identities = 28/102 (27%), Positives = 40/102 (39%), Gaps = 15/102 (14%) Query: 95 PPAYGGISEVNQPAELMPQFSTIEYVIQRGAQSPLIFLYVVDTCLEEDDLQALKESLQMS 154 P YGGIS + + S E + + YV++TC ++ L+ KE +Q Sbjct: 156 PVVYGGISRLQADLNCIRDLSAFE----------VSWKYVINTCGQDFPLKTNKEIVQYL 205 Query: 155 LSL----LPPDALVGLITFGRMVQVHELSCEGISKSYVFRGT 192 + P L GR VH+ G SYV R T Sbjct: 206 KGFKGKNITPGVLPPAHAIGRTKYVHQEHL-GKELSYVIRTT 246 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.322 0.137 0.420 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 30,628,803 Number of Sequences: 37866 Number of extensions: 1420090 Number of successful extensions: 3024 Number of sequences better than 10.0: 14 Number of HSP's better than 10.0 without gapping: 5 Number of HSP's successfully gapped in prelim test: 9 Number of HSP's that attempted gapping in prelim test: 3006 Number of HSP's gapped (non-prelim): 23 length of query: 767 length of database: 18,247,518 effective HSP length: 110 effective length of query: 657 effective length of database: 14,082,258 effective search space: 9252043506 effective search space used: 9252043506 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.