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Search of human proteins with 14589929
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|14589929 protocadherin 18 precursor [Homo sapiens]
(1135 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|14589929 protocadherin 18 precursor [Homo sapiens] 2263 0.0
gi|94538350 protocadherin 17 precursor [Homo sapiens] 659 0.0
gi|14589916 protocadherin 10 isoform 1 precursor [Homo sapiens] 652 0.0
gi|157426845 protocadherin 19 isoform b [Homo sapiens] 635 0.0
gi|157426847 protocadherin 19 isoform a [Homo sapiens] 634 0.0
gi|7706113 protocadherin 12 precursor [Homo sapiens] 593 e-169
gi|14589914 protocadherin 10 isoform 2 precursor [Homo sapiens] 588 e-168
gi|14196468 protocadherin gamma subfamily A, 4 isoform 2 precurs... 487 e-137
gi|11056026 protocadherin gamma subfamily A, 4 isoform 1 precurs... 487 e-137
gi|8850232 protocadherin gamma subfamily A, 12 isoform 1 precurs... 479 e-135
gi|14196457 protocadherin gamma subfamily A, 12 isoform 2 precur... 479 e-135
gi|11128041 protocadherin gamma subfamily A, 10 isoform 1 precur... 478 e-134
gi|14196448 protocadherin gamma subfamily A, 10 isoform 2 precur... 478 e-134
gi|9256586 protocadherin alpha 3 isoform 1 precursor [Homo sapiens] 473 e-133
gi|14165410 protocadherin alpha 3 isoform 2 precursor [Homo sapi... 473 e-133
gi|14165400 protocadherin alpha 1 isoform 2 precursor [Homo sapi... 471 e-132
gi|9256582 protocadherin alpha 1 isoform 1 precursor [Homo sapiens] 471 e-132
gi|14196471 protocadherin gamma subfamily A, 5 isoform 2 precurs... 468 e-131
gi|11056024 protocadherin gamma subfamily A, 5 isoform 1 precurs... 468 e-131
gi|11128043 protocadherin gamma subfamily A, 9 isoform 1 precurs... 466 e-131
gi|14270487 protocadherin gamma subfamily A, 9 isoform 2 precurs... 466 e-131
gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens] 465 e-130
gi|14165416 protocadherin alpha 5 isoform 2 precursor [Homo sapi... 465 e-130
gi|11056032 protocadherin gamma subfamily A, 1 isoform 1 precurs... 464 e-130
gi|14196459 protocadherin gamma subfamily A, 1 isoform 2 precurs... 464 e-130
gi|14270499 protocadherin gamma subfamily B, 4 isoform 2 precurs... 464 e-130
gi|13470082 protocadherin gamma subfamily B, 4 isoform 1 precurs... 464 e-130
gi|14196451 protocadherin gamma subfamily A, 11 isoform 2 precur... 462 e-130
gi|11128039 protocadherin gamma subfamily A, 11 isoform 1 precur... 462 e-130
gi|14589880 protocadherin gamma subfamily A, 3 isoform 1 precurs... 462 e-130
>gi|14589929 protocadherin 18 precursor [Homo sapiens]
Length = 1135
Score = 2263 bits (5864), Expect = 0.0
Identities = 1135/1135 (100%), Positives = 1135/1135 (100%)
Query: 1 MHQMNAKMHFRFVFALLIVSFNHDVLGKNLKYRIYEEQRVGSVIARLSEDVADVLLKLPN 60
MHQMNAKMHFRFVFALLIVSFNHDVLGKNLKYRIYEEQRVGSVIARLSEDVADVLLKLPN
Sbjct: 1 MHQMNAKMHFRFVFALLIVSFNHDVLGKNLKYRIYEEQRVGSVIARLSEDVADVLLKLPN 60
Query: 61 PSTVRFRAMQRGNSPLLVVNEDNGEISIGATIDREQLCQKNLNCSIEFDVITLPTEHLQL 120
PSTVRFRAMQRGNSPLLVVNEDNGEISIGATIDREQLCQKNLNCSIEFDVITLPTEHLQL
Sbjct: 61 PSTVRFRAMQRGNSPLLVVNEDNGEISIGATIDREQLCQKNLNCSIEFDVITLPTEHLQL 120
Query: 121 FHIEVEVLDINDNSPQFSRSLIPIEISESAAVGTRIPLDSAFDPDVGENSLHTYSLSAND 180
FHIEVEVLDINDNSPQFSRSLIPIEISESAAVGTRIPLDSAFDPDVGENSLHTYSLSAND
Sbjct: 121 FHIEVEVLDINDNSPQFSRSLIPIEISESAAVGTRIPLDSAFDPDVGENSLHTYSLSAND 180
Query: 181 FFNIEVRTRTDGAKYAELIVVRELDRELKSSYELQLTASDMGVPQRSGSSILKISISDSN 240
FFNIEVRTRTDGAKYAELIVVRELDRELKSSYELQLTASDMGVPQRSGSSILKISISDSN
Sbjct: 181 FFNIEVRTRTDGAKYAELIVVRELDRELKSSYELQLTASDMGVPQRSGSSILKISISDSN 240
Query: 241 DNSPAFEQQSYIIQLLENSPVGTLLLDLNATDPDEGANGKIVYSFSSHVSPKIMETFKID 300
DNSPAFEQQSYIIQLLENSPVGTLLLDLNATDPDEGANGKIVYSFSSHVSPKIMETFKID
Sbjct: 241 DNSPAFEQQSYIIQLLENSPVGTLLLDLNATDPDEGANGKIVYSFSSHVSPKIMETFKID 300
Query: 301 SERGHLTLFKQVDYEITKSYEIDVQAQDLGPNSIPAHCKIIIKVVDVNDNKPEININLMS 360
SERGHLTLFKQVDYEITKSYEIDVQAQDLGPNSIPAHCKIIIKVVDVNDNKPEININLMS
Sbjct: 301 SERGHLTLFKQVDYEITKSYEIDVQAQDLGPNSIPAHCKIIIKVVDVNDNKPEININLMS 360
Query: 361 PGKEEISYIFEGDPIDTFVALVRVQDKDSGLNGEIVCKLHGHGHFKLQKTYENNYLILTN 420
PGKEEISYIFEGDPIDTFVALVRVQDKDSGLNGEIVCKLHGHGHFKLQKTYENNYLILTN
Sbjct: 361 PGKEEISYIFEGDPIDTFVALVRVQDKDSGLNGEIVCKLHGHGHFKLQKTYENNYLILTN 420
Query: 421 ATLDREKRSEYSLTVIAEDRGTPSLSTVKHFTVQINDINDNPPHFQRSRYEFVISENNSP 480
ATLDREKRSEYSLTVIAEDRGTPSLSTVKHFTVQINDINDNPPHFQRSRYEFVISENNSP
Sbjct: 421 ATLDREKRSEYSLTVIAEDRGTPSLSTVKHFTVQINDINDNPPHFQRSRYEFVISENNSP 480
Query: 481 GAYITTVTATDPDLGENGQVTYTILESFILGSSITTYVTIDPSNGAIYALRIFDHEEVSQ 540
GAYITTVTATDPDLGENGQVTYTILESFILGSSITTYVTIDPSNGAIYALRIFDHEEVSQ
Sbjct: 481 GAYITTVTATDPDLGENGQVTYTILESFILGSSITTYVTIDPSNGAIYALRIFDHEEVSQ 540
Query: 541 ITFVVEARDGGSPKQLVSNTTVVLTIIDENDNVPVVIGPALRNNTAEITIPKGAESGFHV 600
ITFVVEARDGGSPKQLVSNTTVVLTIIDENDNVPVVIGPALRNNTAEITIPKGAESGFHV
Sbjct: 541 ITFVVEARDGGSPKQLVSNTTVVLTIIDENDNVPVVIGPALRNNTAEITIPKGAESGFHV 600
Query: 601 TRIRAIDRDSGVNAELSCAIVAGNEENIFIIDPRSCDIHTNVSMDSVPYTEWELSVIIQD 660
TRIRAIDRDSGVNAELSCAIVAGNEENIFIIDPRSCDIHTNVSMDSVPYTEWELSVIIQD
Sbjct: 601 TRIRAIDRDSGVNAELSCAIVAGNEENIFIIDPRSCDIHTNVSMDSVPYTEWELSVIIQD 660
Query: 661 KGNPQLHTKVLLKCMIFEYAESVTSTAMTSVSQASLDVSMIIIISLGAICAVLLVIMVLF 720
KGNPQLHTKVLLKCMIFEYAESVTSTAMTSVSQASLDVSMIIIISLGAICAVLLVIMVLF
Sbjct: 661 KGNPQLHTKVLLKCMIFEYAESVTSTAMTSVSQASLDVSMIIIISLGAICAVLLVIMVLF 720
Query: 721 ATRCNREKKDTRSYNCRVAESTYQHHPKRPSRQIHKGDITLVPTINGTLPIRSHHRSSPS 780
ATRCNREKKDTRSYNCRVAESTYQHHPKRPSRQIHKGDITLVPTINGTLPIRSHHRSSPS
Sbjct: 721 ATRCNREKKDTRSYNCRVAESTYQHHPKRPSRQIHKGDITLVPTINGTLPIRSHHRSSPS 780
Query: 781 SSPTLERGQMGSRQSHNSHQSLNSLVTISSNHVPENFSLELTHATPAVEQVSQLLSMLHQ 840
SSPTLERGQMGSRQSHNSHQSLNSLVTISSNHVPENFSLELTHATPAVEQVSQLLSMLHQ
Sbjct: 781 SSPTLERGQMGSRQSHNSHQSLNSLVTISSNHVPENFSLELTHATPAVEQVSQLLSMLHQ 840
Query: 841 GQYQPRPSFRGNKYSRSYRYALQDMDKFSLKDSGRGDSEAGDSDYDLGRDSPIDRLLGEG 900
GQYQPRPSFRGNKYSRSYRYALQDMDKFSLKDSGRGDSEAGDSDYDLGRDSPIDRLLGEG
Sbjct: 841 GQYQPRPSFRGNKYSRSYRYALQDMDKFSLKDSGRGDSEAGDSDYDLGRDSPIDRLLGEG 900
Query: 901 FSDLFLTDGRIPAAMRLCTEECRVLGHSDQCWMPPLPSPSSDYRSNMFIPGEEFPTQPQQ 960
FSDLFLTDGRIPAAMRLCTEECRVLGHSDQCWMPPLPSPSSDYRSNMFIPGEEFPTQPQQ
Sbjct: 901 FSDLFLTDGRIPAAMRLCTEECRVLGHSDQCWMPPLPSPSSDYRSNMFIPGEEFPTQPQQ 960
Query: 961 QHPHQSLEDDAQPADSGEKKKSFSTFGKDSPNDEDTGDTSTSSLLSEMSSVFQRLLPPSL 1020
QHPHQSLEDDAQPADSGEKKKSFSTFGKDSPNDEDTGDTSTSSLLSEMSSVFQRLLPPSL
Sbjct: 961 QHPHQSLEDDAQPADSGEKKKSFSTFGKDSPNDEDTGDTSTSSLLSEMSSVFQRLLPPSL 1020
Query: 1021 DTYSECSEVDRSNSLERRKGPLPAKTVGYPQGVAAWAASTHFQNPTTNCGPPLGTHSSVQ 1080
DTYSECSEVDRSNSLERRKGPLPAKTVGYPQGVAAWAASTHFQNPTTNCGPPLGTHSSVQ
Sbjct: 1021 DTYSECSEVDRSNSLERRKGPLPAKTVGYPQGVAAWAASTHFQNPTTNCGPPLGTHSSVQ 1080
Query: 1081 PSSKWLPAMEEIPENYEEDDFDNVLNHLNDGKHELMDASELVAEINKLLQDVRQS 1135
PSSKWLPAMEEIPENYEEDDFDNVLNHLNDGKHELMDASELVAEINKLLQDVRQS
Sbjct: 1081 PSSKWLPAMEEIPENYEEDDFDNVLNHLNDGKHELMDASELVAEINKLLQDVRQS 1135
>gi|94538350 protocadherin 17 precursor [Homo sapiens]
Length = 1159
Score = 659 bits (1701), Expect = 0.0
Identities = 428/1178 (36%), Positives = 633/1178 (53%), Gaps = 118/1178 (10%)
Query: 28 KNLKYRIYEEQRVGSVIARLSEDVADVLLKLP--------NPSTVRFRAMQRGNSPLLVV 79
KNL Y + EEQ G+VI + D A + LP + +R ++ LL V
Sbjct: 19 KNLNYSVPEEQGAGTVIGNIGRD-ARLQPGLPPAERGGGGRSKSGSYRVLENSAPHLLDV 77
Query: 80 NEDNGEISIGATIDREQLCQKNLNCSIEFDVITLPTEHLQLFHIEVEVLDINDNSPQFSR 139
+ D+G + IDRE LC+ N C + +V E + I+VE+ DINDN+P FS
Sbjct: 78 DADSGLLYTKQRIDRESLCRHNAKCQLSLEVFANDKE---ICMIKVEIQDINDNAPSFSS 134
Query: 140 SLIPIEISESAAVGTRIPLDSAFDPDVGENSLHTYSLSAND--FFNIEVRTRTDGAKYAE 197
I ++ISE+AA GTR PL SA DPD GEN L TY L+ +D F ++V++R DG K+ E
Sbjct: 135 DQIEMDISENAAPGTRFPLTSAHDPDAGENGLRTYLLTRDDHGLFGLDVKSRGDGTKFPE 194
Query: 198 LIVVRELDRELKSSYELQLTASDMGVPQRSGSSILKISISDSNDNSPAFEQQSYIIQLLE 257
L++ + LDRE ++ + L LTA D G P RS + + + + DSNDNSP FE SY+++L E
Sbjct: 195 LVIQKALDREQQNHHTLVLTALDGGEPPRSATVQINVKVIDSNDNSPVFEAPSYLVELPE 254
Query: 258 NSPVGTLLLDLNATDPDEGANGKIVYSFSSHVSPKIMETFKIDSERGHLTLFKQVDYEIT 317
N+P+GT+++DLNATD DEG NG+++YSFSS+V ++ E F ID + G + + +DYE
Sbjct: 255 NAPLGTVVIDLNATDADEGPNGEVLYSFSSYVPDRVRELFSIDPKTGLIRVKGNLDYEEN 314
Query: 318 KSYEIDVQAQDLGPNSIPAHCKIIIKVVDVNDNKPEININLMSPGKEEISYIFEGDPIDT 377
EIDVQA+DLGPN IPAHCK+ +K++D NDN P I + G + E P T
Sbjct: 315 GMLEIDVQARDLGPNPIPAHCKVTVKLIDRNDNAPSIGFVSVRQGA-----LSEAAPPGT 369
Query: 378 FVALVRVQDKDSGLNGEIVCKLHGHGH---------------FKLQKTYENNYLILTNAT 422
+ALVRV D+DSG NG++ C++ G G FKL++ Y+N Y ++T+
Sbjct: 370 VIALVRVTDRDSGKNGQLQCRVLGGGGTGGGGGLGGPGGSVPFKLEENYDNFYTVVTDRP 429
Query: 423 LDREKRSEYSLTVIAEDRGTPSLSTVKHFTVQINDINDNPPHFQRSRYEFVISENNSPGA 482
LDRE + EY++T++A D G+P L++ K F ++I D NDNPP F + Y + ENN PG
Sbjct: 430 LDRETQDEYNVTIVARDGGSPPLNSTKSFAIKILDENDNPPRFTKGLYVLQVHENNIPGE 489
Query: 483 YITTVTATDPDLGENGQVTYTILESFILGSSITTYVTIDPSNGAIYALRIFDHEEVSQIT 542
Y+ +V A DPDLG+NG V+Y+IL S I SI TYV+++P+NGAIYALR F+ E+
Sbjct: 490 YLGSVLAQDPDLGQNGTVSYSILPSHIGDVSIYTYVSVNPTNGAIYALRSFNFEQTKAFE 549
Query: 543 FVVEARDGGSPKQLVSNTTVVLTIIDENDNVPVVIGPALRNNTAEITIPKGAESGFHVTR 602
F V A+D G+P L SN TV +T++D NDN PV++ P L+N+TAE+ +P+ A G+ V+
Sbjct: 550 FKVLAKDSGAPAHLESNATVRVTVLDVNDNAPVIVLPTLQNDTAELQVPRNAGLGYLVST 609
Query: 603 IRAIDRDSGVNAELSCAIVAGNEENIFIIDPRSCDIHTNVSM--DSVPYTEWELSVIIQD 660
+RA+D D G + L+ IV GN++++F IDP S +I T D P EL V + D
Sbjct: 610 VRALDSDFGESGRLTYEIVDGNDDHLFEIDPSSGEIRTLHPFWEDVTPVV--ELVVKVTD 667
Query: 661 KGNPQLH--TKVLLKCMIFEYAESVTSTAMTSVSQASLDVSMIIIISLGAICAVLLVIMV 718
G P L K++++ + E V + Q D+S+ +I++L I +LL M+
Sbjct: 668 HGKPTLSAVAKLIIRSVSGSLPEGV---PRVNGEQHHWDMSLPLIVTLSTISIILLAAMI 724
Query: 719 LFATRCNREKKDTRSYNCRVAESTYQHHP-----KRPSRQIHKGDITLVPTINGTLPIRS 773
A +C RE K+ R+YNCR+AE + HP K ++I+K DI LV + +
Sbjct: 725 TIAVKCKRENKEIRTYNCRIAEYS---HPQLGGGKGKKKKINKNDIMLVQ--SEVEERNA 779
Query: 774 HHRSSPSSSPTLERGQM----GSRQSHNSHQSLNSLVTISSNH--VPENFSLELT----H 823
+ + SSP+L M +R +S +S + +SN+ VP+ + T
Sbjct: 780 MNVMNVVSSPSLATSPMYFDYQTRLPLSSPRSEVMYLKPASNNLTVPQGHAGCHTSFTGQ 839
Query: 824 ATPAVEQVSQLLSMLHQGQYQPRPSFRGNKYS-RSYRYALQDMDKFSLKDSGRGDSEAGD 882
T A E + +S++ + P++ G++ +D ++ SL+DSG GDS+ D
Sbjct: 840 GTNASETPATRMSIIQTDNFPAEPNYMGSRQQFVQSSSTFKDPERASLRDSGHGDSDQAD 899
Query: 883 SDYDLGRDSPIDRLLGEGFSDLFLTDGRIPAAMR-----LCTEECRVLGHSDQCWMPPLP 937
SD D + S D + E + P CT+ECRVLGHSD+CWMP P
Sbjct: 900 SDQDTNKGSCCDMSVREALKMKTTSTKSQPLEQEPEECVNCTDECRVLGHSDRCWMPQFP 959
Query: 938 ----SPSSDYRSNMFIPGEEFPTQPQQQHPHQSLEDDAQPADSGEKKKSFSTFGKDSPND 993
+ ++DYR+N+F+P E ++E + + KK+F TFGKD
Sbjct: 960 AANQAENADYRTNLFVPTVE-----------ANVETETYETVNPTGKKTFCTFGKDK--- 1005
Query: 994 EDTGDTSTSSLLSEMSSVF--QRLLPPSLDTYSECSEVDRSNSLE---RRKGPLPAKTVG 1048
+ L++ + +R L P L S +E KG L
Sbjct: 1006 -----REHTILIANVKPYLKAKRALSPLLQEVPSASSSPTKACIEPCTSTKGSLDGCEA- 1059
Query: 1049 YPQGVAAWAASTHFQNPTTNCGPPLGTHSSVQPSSKWLPAMEEIPENY---------EED 1099
G A A+S + + P S QP A +++ + +
Sbjct: 1060 -KPGALAEASSQYLPTDSQYLSP------SKQPRDPPFMASDQMARVFADVHSRASRDSS 1112
Query: 1100 DFDNVLNHLN----DGKHELMDASELVAEINKLLQDVR 1133
+ VL L+ D E +DA E+V EI+KLLQD R
Sbjct: 1113 EMGAVLEQLDHPNRDLGRESVDAEEVVREIDKLLQDCR 1150
>gi|14589916 protocadherin 10 isoform 1 precursor [Homo sapiens]
Length = 1040
Score = 652 bits (1681), Expect = 0.0
Identities = 398/1034 (38%), Positives = 587/1034 (56%), Gaps = 121/1034 (11%)
Query: 30 LKYRIYEEQRVGSVIARLSEDVADVLLKLPNPSTVRFRAMQRGNSPLLVVNEDNGEISIG 89
L Y + EEQ G+ + ++ED+ + KL S F+ + +P L +N + G + +
Sbjct: 20 LHYTVQEEQEHGTFVGNIAEDLGLDITKL---SARGFQTVPNSRTPYLDLNLETGVLYVN 76
Query: 90 ATIDREQLCQKNLNCSIEFDVITLPTEHLQLFHIEVEVLDINDNSPQFSRSLIPIEISES 149
IDREQ+C+++ +C + +V L+LF +E+EVLDINDN P F + +EISES
Sbjct: 77 EKIDREQICKQSPSCVLHLEVFL--ENPLELFQVEIEVLDINDNPPSFPEPDLTVEISES 134
Query: 150 AAVGTRIPLDSAFDPDVGENSLHTYSLSANDFFNIEVRTRTDGAKYAELIVVRELDRELK 209
A GTR PL+SAFDPDVG NSL Y ++ N +F+++V+T+ DG ++AEL++ + LDRE +
Sbjct: 135 ATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRFAELVLEKPLDREQQ 194
Query: 210 SSYELQLTASD----------------MGVP---QRSGSSILKISISDSNDNSPAFEQQS 250
+ + LTA D G+P QR+G+++L I + DSNDN PAF+Q
Sbjct: 195 AVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVLDSNDNVPAFDQPV 254
Query: 251 YIIQLLENSPVGTLLLDLNATDPDEGANGKIVYSFSSHVSPKIMETFKIDSERGHLTLFK 310
Y + L ENSP GTL++ LNATDPDEG NG++VYSFSSH+SP+ E F + G L +
Sbjct: 255 YTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELFGLSPRTGRLEVSG 314
Query: 311 QVDYEITKSYEIDVQAQDLGPNSIPAHCKIIIKVVDVNDNKPEININLMSPGKEEISYIF 370
++DYE + Y++ VQA+DLGPN++PAHCK++++V+D NDN PEI+ + + KE +S
Sbjct: 315 ELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFSTV---KEAVS--- 368
Query: 371 EGDPIDTFVALVRVQDKDSGLNGEIVCKLHGHGHFKLQKTYENNYLILTNATLDREKRSE 430
EG T VAL V D+DS NG++ C+L G F+L+ +++N Y I+T A LDRE
Sbjct: 369 EGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAPLDREAGDS 428
Query: 431 YSLTVIAEDRGTPSLSTVKHFTVQINDINDNPPHFQRSRYEFVISENNSPGAYITTVTAT 490
Y+LTV+A DRG P+LST K VQ++D+NDN P F + Y+ ++ENN PGAYI V+AT
Sbjct: 429 YTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYIYAVSAT 488
Query: 491 DPDLGENGQVTYTILESFILGSSITTYVTIDPSNGAIYALRIFDHEEVSQITFVVEARDG 550
D D G N Q+ Y+ILE I G S+ TYV+I+ NG +YALR FD+E++ +F VEARD
Sbjct: 489 DRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSFQVEARDA 548
Query: 551 GSPKQLVSNTTVVLTIIDENDNVPVVIGPAL-RNNT-AEITIPKGAESGFHVTRIRAIDR 608
GSP+ L N TV + I+D+NDN P ++ P RN T A +P+ AE G+ +TR+ A+D
Sbjct: 549 GSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLLTRVAAVDA 608
Query: 609 DSGVNAELSCAIVAGNEENIFIIDPRSCDIHT--NVSMDSVPYTEWELSVIIQDKGNPQL 666
D G NA L+ +IV GNE N+F +D R+ ++ T V P +EL + ++D G P L
Sbjct: 609 DDGENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEVRDHGQPPL 668
Query: 667 HTKVLLKCMIFEYAESVTS--------------TAMTSVSQASLDVSMIIIISLGAICAV 712
+ L + + A + + + SLD+++I+II+LG++ +
Sbjct: 669 SSTATLVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLTLILIIALGSVSFI 728
Query: 713 LLVIMVLFATRCNREKKDTRSYNCRVAE-------------STYQHHPKRPSRQIHKGDI 759
L+ M++ A RC +EKK Y C ++ + + +++ K DI
Sbjct: 729 FLLAMIVLAVRCQKEKK-LNIYTCLASDCCLCCCCCGGGGSTCCGRQARARKKKLSKSDI 787
Query: 760 TLVPTINGTLPIRSHHRSSPSSSPTLERGQMGSRQSHNSHQSLNSLVTISSNHVPENF-- 817
LV + N +P S+P+ P E G GS HN + +T S F
Sbjct: 788 MLVQSSN--VP------SNPAQVPIEESGGFGSHH-HNQNYCYQVCLTPESAKTDLMFLK 838
Query: 818 ------SLELTH------ATPAVEQVSQLLS----MLHQGQYQ-PRPSFRGNKYSRSYRY 860
S + H T +Q ++S + ++ ++Q S+ ++ R
Sbjct: 839 PCSPSRSTDTEHNPCGAIVTGYTDQQPDIISNGSILSNETKHQRAELSYLVDRPRRVNSS 898
Query: 861 ALQDMDKFSLKDSGRGDSEAGDSDYDLGRDSPIDRLLGEGFSDLFLTDGRIPAAMRLCTE 920
A Q+ D S KDSG GDSE GDSD+D +R G DLF CTE
Sbjct: 899 AFQEADIVSSKDSGHGDSEQGDSDHD-----ATNRAQSAGM-DLFSN----------CTE 942
Query: 921 ECRVLGHSDQCWMPP-LPS---PSSDYRSNMFIPG-EEFPTQPQQQHPHQSLEDDAQPAD 975
EC+ LGHSD+CWMP +PS ++DYRSN+ +PG + P + P +AQP
Sbjct: 943 ECKALGHSDRCWMPSFVPSDGRQAADYRSNLHVPGMDSVPDTEVFETP------EAQPG- 995
Query: 976 SGEKKKSFSTFGKD 989
++SFSTFGK+
Sbjct: 996 ---AERSFSTFGKE 1006
>gi|157426845 protocadherin 19 isoform b [Homo sapiens]
Length = 1100
Score = 635 bits (1637), Expect = 0.0
Identities = 388/1079 (35%), Positives = 597/1079 (55%), Gaps = 49/1079 (4%)
Query: 13 VFALLIVSFNHDVLGKNLKYRIYEEQRVGSVIARLSEDVADVLLKLPNPSTVRFRAMQRG 72
V LL + + NLKY + EEQR G+VIA +++D + L FR +
Sbjct: 8 VLLLLAILWTQAAALINLKYSVEEEQRAGTVIANVAKDAREAGFALDPRQASAFRVVSNS 67
Query: 73 NSPLLVVNEDNGEISIGATIDREQLCQKNLNCSIEFDVITLPTEHLQLFHIEVEVLDIND 132
L+ +N +G + IDR+ LC+++ C I +V++ +++ I+VE+ D+ND
Sbjct: 68 APHLVDINPSSGLLVTKQKIDRDLLCRQSPKCIISLEVMS---SSMEICVIKVEIKDLND 124
Query: 133 NSPQFSRSLIPIEISESAAVGTRIPLDSAFDPDVGENSLHTYSLSANDFFNIEVRTRTDG 192
N+P F + I +EISE+A+ GTRIPLDSA+DPD G + TY L+ N+ F +E++TR DG
Sbjct: 125 NAPSFPAAQIELEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNELFGLEIKTRGDG 184
Query: 193 AKYAELIVVRELDRELKSSYELQLTASDMGVPQRSGSSILKISISDSNDNSPAFEQQSYI 252
+++AEL+V + LDRE +S Y ++TA D G P R G+ L I ++DSNDN+P F + +Y
Sbjct: 185 SRFAELVVEKSLDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNNPVFSESTYA 244
Query: 253 IQLLENSPVGTLLLDLNATDPDEGANGKIVYSFSSHVSPKIMETFKIDSERGHLTLFKQV 312
+ + ENSP T ++ LNA+DPDEG NG++VYSF +V+ + E F+ID G +T+ +
Sbjct: 245 VSVPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHSGLVTVTGAL 304
Query: 313 DYEITKSYEIDVQAQDLGPNSIPAHCKIIIKVVDVNDNKPEININLMSPGKEEISYIFEG 372
DYE YE+DVQA+DLGPNSIPAHCK+ + V+D NDN P IN+ ++ E+S E
Sbjct: 305 DYEEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSELVEVS---ES 361
Query: 373 DPIDTFVALVRVQDKDSGLNGEIVCKLHGHGHFKLQKTYENNYLILTNATLDREKRSEYS 432
P +ALVRV D+DSGLNG + C+L G+ F+LQ+ YE+ IL + LDRE+ +Y+
Sbjct: 362 APPGYVIALVRVSDRDSGLNGRVQCRLLGNVPFRLQE-YESFSTILVDGRLDREQHDQYN 420
Query: 433 LTVIAEDRGTPSLSTVKHFTVQINDINDNPPHFQRSRYEFVISENNSPGAYITTVTATDP 492
LT+ A D G P L + K FTV I D NDN PHF + Y+ ++ ENN+PGAY+ +V+A DP
Sbjct: 421 LTIQARDGGVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENNTPGAYLLSVSARDP 480
Query: 493 DLGENGQVTYTILESFILGSSITTYVTIDPSNGAIYALRIFDHEEVSQITFVVEARDGGS 552
DLG NG V+Y I+ S + + TYV+I+P++G IYALR F+HE+ F V A+DGG
Sbjct: 481 DLGLNGSVSYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTKAFEFKVLAKDGGL 540
Query: 553 PKQLVSNTTVVLTIIDENDNVPVVIGPALRNNTAEITIPKGAESGFHVTRIRAIDRDSGV 612
P L SN TV + I+D NDN PV+ P L N TAE+ IP+ + G+ VT ++A D D G
Sbjct: 541 P-SLQSNATVRVIILDVNDNTPVITAPPLINGTAEVYIPRNSGIGYLVTVVKAEDYDEGE 599
Query: 613 NAELSCAIVAGNEENIFIIDPRSCDIHTNVSMDSVPYTEWELSVIIQDKGNPQLHTKVLL 672
N ++ + G + F ID + ++ T + + +EL V+ D G L L+
Sbjct: 600 NGRVTYDMTEG-DRGFFEIDQVNGEVRTTRTFGESSKSSYELIVVAHDHGKTSLSASALV 658
Query: 673 KCMIFEYAESVTSTAMTSVSQASLDVSMIIIISLGAICAVLLVIMVLFATRCNREKKDTR 732
+I+ ++ S S+++S+I II+LG+I +L V M+ A +C R+ K+ R
Sbjct: 659 --LIY-----LSPALDAQESMGSVNLSLIFIIALGSIAGILFVTMIFVAIKCKRDNKEIR 711
Query: 733 SYNCRVAESTYQHHPK-RPSRQIHKGDITLVP-TINGTLPIRSHHRSSPSSSPTL----- 785
+YNCR+AE +Y H K ++I K DI LVP + T + SS +SS
Sbjct: 712 TYNCRIAEYSYGHQKKSSKKKKISKNDIRLVPRDVEETDKMNVVSCSSLTSSLNYFDYHQ 771
Query: 786 ERGQMGSRQSHNSHQSLNSLVT--ISSNHVPENFSLELTHATPAVEQVSQLLSMLHQGQY 843
+ +G R+S ++ ++ + T S+NH+ + P + + + + Y
Sbjct: 772 QTLPLGCRRSESTFLNVENQNTRNTSANHIYHHSFNSQGPQQP--DLIINGVPLPETENY 829
Query: 844 QPRPSFRGNKYSRSYRYALQDMDKFSLKDSGRGDSEAGDSDYDLGRDSPIDRLLGEGFSD 903
++ ++ +D++ SLKDSG +S+ DS++D+ R D + + +
Sbjct: 830 SFDSNYVNSRAHLIKSSTFKDLEGNSLKDSGHEESDQTDSEHDVQRSLYCDTAVNDVLNT 889
Query: 904 LFLTDG-RIPAAMR----LCTEECRVLGHSDQCWMP----PLPSPSSDYRSNMFIPGEEF 954
+ G ++P + C EECR+LGHSD+CWMP P+ S S ++ N+ E
Sbjct: 890 SVTSMGSQMPDHDQNEGFHCREECRILGHSDRCWMPRNPMPIRSKSPEHVRNIIALSIEA 949
Query: 955 PTQPQQQHPHQSLEDDAQPADSGEKKKSFSTFGKD-SPNDEDTGDTSTSSLLSEMSSVFQ 1013
+ + D G K++F+TFGKD S + + T +++
Sbjct: 950 TAADVEAYD-----------DCGPTKRTFATFGKDVSDHPAEERPTLKGKRTVDVTICSP 998
Query: 1014 RLLPPSLDTYSECSEVDRSNSLERRKGPLPAK-TVGYPQGVAAWAASTHFQNPTTNCGP 1071
++ + + C + S K LP K +V Y +A A N GP
Sbjct: 999 KVNSVIREAGNGCEAISPVTSPLHLKSSLPTKPSVSYTIALAPPARDLEQYVNNVNNGP 1057
>gi|157426847 protocadherin 19 isoform a [Homo sapiens]
Length = 1101
Score = 634 bits (1636), Expect = 0.0
Identities = 390/1089 (35%), Positives = 600/1089 (55%), Gaps = 68/1089 (6%)
Query: 13 VFALLIVSFNHDVLGKNLKYRIYEEQRVGSVIARLSEDVADVLLKLPNPSTVRFRAMQRG 72
V LL + + NLKY + EEQR G+VIA +++D + L FR +
Sbjct: 8 VLLLLAILWTQAAALINLKYSVEEEQRAGTVIANVAKDAREAGFALDPRQASAFRVVSNS 67
Query: 73 NSPLLVVNEDNGEISIGATIDREQLCQKNLNCSIEFDVITLPTEHLQLFHIEVEVLDIND 132
L+ +N +G + IDR+ LC+++ C I +V++ +++ I+VE+ D+ND
Sbjct: 68 APHLVDINPSSGLLVTKQKIDRDLLCRQSPKCIISLEVMS---SSMEICVIKVEIKDLND 124
Query: 133 NSPQFSRSLIPIEISESAAVGTRIPLDSAFDPDVGENSLHTYSLSANDFFNIEVRTRTDG 192
N+P F + I +EISE+A+ GTRIPLDSA+DPD G + TY L+ N+ F +E++TR DG
Sbjct: 125 NAPSFPAAQIELEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNELFGLEIKTRGDG 184
Query: 193 AKYAELIVVRELDRELKSSYELQLTASDMGVPQRSGSSILKISISDSNDNSPAFEQQSYI 252
+++AEL+V + LDRE +S Y ++TA D G P R G+ L I ++DSNDN+P F + +Y
Sbjct: 185 SRFAELVVEKSLDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNNPVFSESTYA 244
Query: 253 IQLLENSPVGTLLLDLNATDPDEGANGKIVYSFSSHVSPKIMETFKIDSERGHLTLFKQV 312
+ + ENSP T ++ LNA+DPDEG NG++VYSF +V+ + E F+ID G +T+ +
Sbjct: 245 VSVPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHSGLVTVTGAL 304
Query: 313 DYEITKSYEIDVQAQDLGPNSIPAHCKIIIKVVDVNDNKPEININLMSPGKEEISYIFEG 372
DYE YE+DVQA+DLGPNSIPAHCK+ + V+D NDN P IN+ ++ E+S E
Sbjct: 305 DYEEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSELVEVS---ES 361
Query: 373 DPIDTFVALVRVQDKDSGLNGEIVCKLHGHGHFKLQKTYENNYLILTNATLDREKRSEYS 432
P +ALVRV D+DSGLNG + C+L G+ F+LQ+ YE+ IL + LDRE+ +Y+
Sbjct: 362 APPGYVIALVRVSDRDSGLNGRVQCRLLGNVPFRLQE-YESFSTILVDGRLDREQHDQYN 420
Query: 433 LTVIAEDRGTPSLSTVKHFTVQINDINDNPPHFQRSRYEFVISENNSPGAYITTVTATDP 492
LT+ A D G P L + K FTV I D NDN PHF + Y+ ++ ENN+PGAY+ +V+A DP
Sbjct: 421 LTIQARDGGVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENNTPGAYLLSVSARDP 480
Query: 493 DLGENGQVTYTILESFILGSSITTYVTIDPSNGAIYALRIFDHEEVSQITFVVEARDGGS 552
DLG NG V+Y I+ S + + TYV+I+P++G IYALR F+HE+ F V A+DGG
Sbjct: 481 DLGLNGSVSYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTKAFEFKVLAKDGGL 540
Query: 553 PKQLVSNTTVVLTIIDENDNVPVVIGPALRNNTAEITIPKGAESGFHVTRIRAIDRDSGV 612
P L SN TV + I+D NDN PV+ P L N TAE+ IP+ + G+ VT ++A D D G
Sbjct: 541 P-SLQSNATVRVIILDVNDNTPVITAPPLINGTAEVYIPRNSGIGYLVTVVKAEDYDEGE 599
Query: 613 NAELSCAIVAGNEENIFIIDPRSCDIHTNVSMDSVPYTEWELSVIIQDKGNPQLHTKVLL 672
N ++ + G + F ID + ++ T + + +EL V+ D G L L+
Sbjct: 600 NGRVTYDMTEG-DRGFFEIDQVNGEVRTTRTFGESSKSSYELIVVAHDHGKTSLSASALV 658
Query: 673 KCMIFEYAESVTSTAMTSVSQASLDVSMIIIISLGAICAVLLVIMVLFATRCNREKKDTR 732
+I+ ++ S S+++S+I II+LG+I +L V M+ A +C R+ K+ R
Sbjct: 659 --LIY-----LSPALDAQESMGSVNLSLIFIIALGSIAGILFVTMIFVAIKCKRDNKEIR 711
Query: 733 SYNCRVAESTYQHHPK-RPSRQIHKGDITLVP-TINGTLPIRSHHRSSPSSSPTL----- 785
+YNCR+AE +Y H K ++I K DI LVP + T + SS +SS
Sbjct: 712 TYNCRIAEYSYGHQKKSSKKKKISKNDIRLVPRDVEETDKMNVVSCSSLTSSLNYFDYHQ 771
Query: 786 ERGQMGSRQSHNSHQSLNSLVT--ISSNHVPENFSLELTHATPAVEQVSQLLSMLHQGQY 843
+ +G R+S ++ ++ + T S+NH+ + + + +Q +++ +
Sbjct: 772 QTLPLGCRRSESTFLNVENQNTRNTSANHIYHH-----SFNSQGPQQPDLIINGV----- 821
Query: 844 QPRPSFRGNKYSRSY----------RYALQDMDKFSLKDSGRGDSEAGDSDYDLGRDSPI 893
P P + +Y +D++ SLKDSG +S+ DS++D+ R
Sbjct: 822 -PLPETENYSFDSNYVNSRAHLIKSSSTFKDLEGNSLKDSGHEESDQTDSEHDVQRSLYC 880
Query: 894 DRLLGEGFSDLFLTDG-RIPAAMR----LCTEECRVLGHSDQCWMP----PLPSPSSDYR 944
D + + + + G ++P + C EECR+LGHSD+CWMP P+ S S ++
Sbjct: 881 DTAVNDVLNTSVTSMGSQMPDHDQNEGFHCREECRILGHSDRCWMPRNPMPIRSKSPEHV 940
Query: 945 SNMFIPGEEFPTQPQQQHPHQSLEDDAQPADSGEKKKSFSTFGKD-SPNDEDTGDTSTSS 1003
N+ E + + D G K++F+TFGKD S + + T
Sbjct: 941 RNIIALSIEATAADVEAYD-----------DCGPTKRTFATFGKDVSDHPAEERPTLKGK 989
Query: 1004 LLSEMSSVFQRLLPPSLDTYSECSEVDRSNSLERRKGPLPAK-TVGYPQGVAAWAASTHF 1062
+++ ++ + + C + S K LP K +V Y +A A
Sbjct: 990 RTVDVTICSPKVNSVIREAGNGCEAISPVTSPLHLKSSLPTKPSVSYTIALAPPARDLEQ 1049
Query: 1063 QNPTTNCGP 1071
N GP
Sbjct: 1050 YVNNVNNGP 1058
>gi|7706113 protocadherin 12 precursor [Homo sapiens]
Length = 1184
Score = 593 bits (1529), Expect = e-169
Identities = 323/783 (41%), Positives = 486/783 (62%), Gaps = 48/783 (6%)
Query: 16 LLIVSFNHDVLGKNLKYRIYEEQRVGSVIARLSEDVADVLLKLPNPSTVRFRAMQRGNSP 75
L ++ +V +KY++ EE G+VI +LS+++ + + F+ +Q +
Sbjct: 18 LFLLGDCQEVTTLTVKYQVSEEVPSGTVIGKLSQELGREERR--RQAGAAFQVLQLPQAL 75
Query: 76 LLVVNEDNGEISIGATIDREQLCQKNLNCSIEFDVITLPTEHLQLFHIEVEVLDINDNSP 135
+ V+ + G +S G +DREQLC++ C + FDV L T L L H+E++VLDIND+ P
Sbjct: 76 PIQVDSEEGLLSTGRRLDREQLCRQWDPCLVSFDV--LATGDLALIHVEIQVLDINDHQP 133
Query: 136 QFSRSLIPIEISESAAVGTRIPLDSAFDPDVGENSLHTYSLSANDFFNIEVRTRTDGAKY 195
+F + +EISESA++ TRIPLD A DPD G N+LHTY+LS ++ F ++V D K+
Sbjct: 134 RFPKGEQELEISESASLRTRIPLDRALDPDTGPNTLHTYTLSPSEHFALDVIVGPDETKH 193
Query: 196 AELIVVRELDRELKSSYELQLTASDMGVPQRSGSSILKISISDSNDNSPAFEQQSYIIQL 255
AELIVV+ELDRE+ S ++L LTA D G P +SG+S++K+++ DSNDNSPAF + S +++
Sbjct: 194 AELIVVKELDREIHSFFDLVLTAYDNGNPPKSGTSLVKVNVLDSNDNSPAFAESSLALEI 253
Query: 256 LENSPVGTLLLDLNATDPDEGANGKIVYSFSSHVSPKIMETFKIDSERGHLTLFKQVDYE 315
E++ GTLL+ L ATDPD+G NG++ + S H+ P++++TF ID++ G + L + +DYE
Sbjct: 254 QEDAAPGTLLIKLTATDPDQGPNGEVEFFLSKHMPPEVLDTFSIDAKTGQVILRRPLDYE 313
Query: 316 ITKSYEIDVQAQDLGPNSIPAHCKIIIKVVDVNDNKPEININLMSPGKEEISYIFEGDPI 375
+YE+DVQA+DLGPN IPAHCK++IKV+DVNDN P I++ S + S + E P
Sbjct: 314 KNPAYEVDVQARDLGPNPIPAHCKVLIKVLDVNDNIPSIHVTWAS----QPSLVSEALPK 369
Query: 376 DTFVALVRVQDKDSGLNGEIVCKLHGH-GHFKLQKTYENNYLILTNATLDREKRSEYSLT 434
D+F+ALV D DSG NG + C L GHF+L++T N Y++LTNATLDRE+ +Y+LT
Sbjct: 370 DSFIALVMADDLDSGHNGLVHCWLSQELGHFRLKRTNGNTYMLLTNATLDREQWPKYTLT 429
Query: 435 VIAEDRGTPSLSTVKHFTVQINDINDNPPHFQRSRYEFVISENNSPGAYITTVTATDPDL 494
++A+D+G LS K ++QI+DINDN P F++SRYE ENN P ++ T+ A D DL
Sbjct: 430 LLAQDQGLQPLSAKKQLSIQISDINDNAPVFEKSRYEVSTRENNLPSLHLITIKAHDADL 489
Query: 495 GENGQVTYTILESFILGSSITTYVTIDPSNGAIYALRIFDHEEVSQITFVVEARDGGSPK 554
G NG+V+Y I +S + V ID + G + A R ++EE++ F V A D G P
Sbjct: 490 GINGKVSYRIQDS-----PVAHLVAIDSNTGEVTAQRSLNYEEMAGFEFQVIAEDSGQP- 543
Query: 555 QLVSNTTVVLTIIDENDNVPVVIGPALRNNTAEITIPKGAESG----------------- 597
L S+ +V ++++D NDN P V+ P L + A +++ A +G
Sbjct: 544 MLASSVSVWVSLLDANDNAPEVVQPVLSDGKASLSVLVNASTGHLLVPIETPNGLGPAGT 603
Query: 598 ------------FHVTRIRAIDRDSGVNAELSCAIVAGNEENIFIIDPRSCDIHTNVS-M 644
F +T I A D DSG N E +I +GNE ++FI++P + + NV+
Sbjct: 604 DTPPLATHSSRPFLLTTIVARDADSGANGEPLYSIRSGNEAHLFILNPHTGQLFVNVTNA 663
Query: 645 DSVPYTEWELSVIIQDKGNPQLHTKVLLKCMIFEYAESVTSTAMTSVSQASLDVSMIIII 704
S+ +EWEL ++++D+G+P L T+ LL+ M + SV ++ +L +SM+ +I
Sbjct: 664 SSLIGSEWELEIVVEDQGSPPLQTRALLRVM---FVTSVDHLRDSARKPGALSMSMLTVI 720
Query: 705 SLGAICAVLLVIMVLFATRCNREKKDTRSYNCRVAESTYQHHPKRPSRQIHKGDITLVPT 764
L + + +I+ LF + C EKKD R+YNCR AESTY+ PKRP + I K DI LVP
Sbjct: 721 CLAVLLGIFGLILALFMSICRTEKKDNRAYNCREAESTYRQQPKRPQKHIQKADIHLVPV 780
Query: 765 ING 767
+ G
Sbjct: 781 LRG 783
Score = 99.8 bits (247), Expect = 1e-20
Identities = 82/249 (32%), Positives = 118/249 (47%), Gaps = 42/249 (16%)
Query: 779 PSSSPTLER-----GQMGSRQSHNSHQSLNSLVTISSNHVPENFSLE-LTHATPAVEQVS 832
P+SS TL R G++ + Q L SLV +S E +E LT +P V+Q+S
Sbjct: 904 PASSATLRRQRHLNGKVSPEKESGPRQILRSLVRLSVAAFAERNPVEELTVDSPPVQQIS 963
Query: 833 QLLSMLHQGQYQPRPSFRGNKY---SRSYRYALQDMDKFSLKDSGRGDSEAGDSDYDLGR 889
QLLS+LHQGQ+QP+P+ RGNKY R A+ D D S + G+ D E + D
Sbjct: 964 QLLSLLHQGQFQPKPNHRGNKYLAKPGGSRSAIPDTDGPSARAGGQTDPEQEEGPLDPEE 1023
Query: 890 DSPIDRLLGEGFSDLFLTDGRIPAAMRLCTEECRVLGHSDQCWMPPLPSP-SSDYRSNMF 948
D + +LL E S L + + L + L D WM L P +++YR N+
Sbjct: 1024 DLSVKQLLEEELSSL------LDPSTGLALDR---LSAPDPAWMARLSLPLTTNYRDNVI 1074
Query: 949 IPGEEFPTQPQQQHPHQSLEDDAQPADSGEKKKSFSTFGK-DSPNDEDTGDTSTSSLLSE 1007
P A + E+ ++F TFGK ++P TG S+ +SE
Sbjct: 1075 SP----------------------DAAATEEPRTFQTFGKAEAPELSPTGTRLASTFVSE 1112
Query: 1008 MSSVFQRLL 1016
MSS+ + LL
Sbjct: 1113 MSSLLEMLL 1121
>gi|14589914 protocadherin 10 isoform 2 precursor [Homo sapiens]
Length = 896
Score = 588 bits (1516), Expect = e-168
Identities = 335/847 (39%), Positives = 498/847 (58%), Gaps = 77/847 (9%)
Query: 30 LKYRIYEEQRVGSVIARLSEDVADVLLKLPNPSTVRFRAMQRGNSPLLVVNEDNGEISIG 89
L Y + EEQ G+ + ++ED+ + KL S F+ + +P L +N + G + +
Sbjct: 20 LHYTVQEEQEHGTFVGNIAEDLGLDITKL---SARGFQTVPNSRTPYLDLNLETGVLYVN 76
Query: 90 ATIDREQLCQKNLNCSIEFDVITLPTEHLQLFHIEVEVLDINDNSPQFSRSLIPIEISES 149
IDREQ+C+++ +C + +V L+LF +E+EVLDINDN P F + +EISES
Sbjct: 77 EKIDREQICKQSPSCVLHLEVFL--ENPLELFQVEIEVLDINDNPPSFPEPDLTVEISES 134
Query: 150 AAVGTRIPLDSAFDPDVGENSLHTYSLSANDFFNIEVRTRTDGAKYAELIVVRELDRELK 209
A GTR PL+SAFDPDVG NSL Y ++ N +F+++V+T+ DG ++AEL++ + LDRE +
Sbjct: 135 ATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRFAELVLEKPLDREQQ 194
Query: 210 SSYELQLTASD----------------MGVP---QRSGSSILKISISDSNDNSPAFEQQS 250
+ + LTA D G+P QR+G+++L I + DSNDN PAF+Q
Sbjct: 195 AVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVLDSNDNVPAFDQPV 254
Query: 251 YIIQLLENSPVGTLLLDLNATDPDEGANGKIVYSFSSHVSPKIMETFKIDSERGHLTLFK 310
Y + L ENSP GTL++ LNATDPDEG NG++VYSFSSH+SP+ E F + G L +
Sbjct: 255 YTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELFGLSPRTGRLEVSG 314
Query: 311 QVDYEITKSYEIDVQAQDLGPNSIPAHCKIIIKVVDVNDNKPEININLMSPGKEEISYIF 370
++DYE + Y++ VQA+DLGPN++PAHCK++++V+D NDN PEI+ + + KE +S
Sbjct: 315 ELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFSTV---KEAVS--- 368
Query: 371 EGDPIDTFVALVRVQDKDSGLNGEIVCKLHGHGHFKLQKTYENNYLILTNATLDREKRSE 430
EG T VAL V D+DS NG++ C+L G F+L+ +++N Y I+T A LDRE
Sbjct: 369 EGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAPLDREAGDS 428
Query: 431 YSLTVIAEDRGTPSLSTVKHFTVQINDINDNPPHFQRSRYEFVISENNSPGAYITTVTAT 490
Y+LTV+A DRG P+LST K VQ++D+NDN P F + Y+ ++ENN PGAYI V+AT
Sbjct: 429 YTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYIYAVSAT 488
Query: 491 DPDLGENGQVTYTILESFILGSSITTYVTIDPSNGAIYALRIFDHEEVSQITFVVEARDG 550
D D G N Q+ Y+ILE I G S+ TYV+I+ NG +YALR FD+E++ +F VEARD
Sbjct: 489 DRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSFQVEARDA 548
Query: 551 GSPKQLVSNTTVVLTIIDENDNVPVVIGPAL-RNNT-AEITIPKGAESGFHVTRIRAIDR 608
GSP+ L N TV + I+D+NDN P ++ P RN T A +P+ AE G+ +TR+ A+D
Sbjct: 549 GSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLLTRVAAVDA 608
Query: 609 DSGVNAELSCAIVAGNEENIFIIDPRSCDIHT--NVSMDSVPYTEWELSVIIQDKGNPQL 666
D G NA L+ +IV GNE N+F +D R+ ++ T V P +EL + ++D G P L
Sbjct: 609 DDGENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEVRDHGQPPL 668
Query: 667 HTKVLLKCMIFEYAESVTS--------------TAMTSVSQASLDVSMIIIISLGAICAV 712
+ L + + A + + + SLD+++I+II+LG++ +
Sbjct: 669 SSTATLVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLTLILIIALGSVSFI 728
Query: 713 LLVIMVLFATRCNREKKDTRSYNCRVAE-------------STYQHHPKRPSRQIHKGDI 759
L+ M++ A RC +EKK Y C ++ + + +++ K DI
Sbjct: 729 FLLAMIVLAVRCQKEKK-LNIYTCLASDCCLCCCCCGGGGSTCCGRQARARKKKLSKSDI 787
Query: 760 TLVPTINGTLPIRSHHRSSPSSSPTLERGQMGSRQSHNSHQSLNSLVTISSNHVPENFSL 819
LV + N +P S+P+ P E G GS HN + +T PE+
Sbjct: 788 MLVQSSN--VP------SNPAQVPIEESGGFGSHH-HNQNYCYQVCLT------PESAKT 832
Query: 820 ELTHATP 826
+L P
Sbjct: 833 DLMFLKP 839
>gi|14196468 protocadherin gamma subfamily A, 4 isoform 2 precursor
[Homo sapiens]
Length = 820
Score = 487 bits (1253), Expect = e-137
Identities = 269/727 (37%), Positives = 427/727 (58%), Gaps = 21/727 (2%)
Query: 9 HFRFVFALLIVSFNHDVLGKNLKYRIYEEQRVGSVIARLSEDVADVLLKLPNPSTVRFRA 68
H R + L++ ++ + + Y ++EEQ GSV+ +++D+ +L R
Sbjct: 10 HTRLLQICLLLGVLVEIRAEQILYSVFEEQEEGSVVGNIAKDLGLAPRELAERGV---RI 66
Query: 69 MQRGNSPLLVVNEDNGEISIGATIDREQLCQKNLNCSIEFDVITLPTEHLQLFHIEVEVL 128
+ RG + L +N +G + IDRE+LC ++ NC +++ T +++ +EVE++
Sbjct: 67 VSRGRTQLFALNPRSGTLVTAGRIDREELCDRSPNCVTNLEILLEDT--VKILRVEVEII 124
Query: 129 DINDNSPQFSRSLIPIEISESAAVGTRIPLDSAFDPDVGENSLHTYSLSANDFFNIEVRT 188
D+NDN P F I+++E+ G R PL AFDPDVG NSL Y L++N +F+++V++
Sbjct: 125 DVNDNPPSFGTEQREIKVAENENPGARFPLPEAFDPDVGVNSLQGYQLNSNGYFSLDVQS 184
Query: 189 RTDGAKYAELIVVRELDRELKSSYELQLTASDMGVPQRSGSSILKISISDSNDNSPAFEQ 248
DG KY EL++ R LDRE ++ + L LTA D G P RSG++ + I + D+NDN+P F Q
Sbjct: 185 GADGIKYPELVLERALDREEEAVHHLVLTAFDGGDPVRSGTARILIILVDTNDNAPVFTQ 244
Query: 249 QSYIIQLLENSPVGTLLLDLNATDPDEGANGKIVYSFSSHVSPKIMETFKIDSERGHLTL 308
Y + + EN PVGT LL + ATDPDEGANG + YSF V KI + F+++S G +T+
Sbjct: 245 PEYHVSVRENVPVGTRLLTVKATDPDEGANGDVTYSFRK-VRDKISQLFQLNSLSGDITI 303
Query: 309 FKQVDYEITKSYEIDVQAQDLGPNSIPAHCKIIIKVVDVNDNKPEININLMSPGKEEISY 368
+DYE + Y+IDV+A D GP + A K+++ V+D NDN PE+ + ++ S
Sbjct: 304 LGGLDYEDSGFYDIDVEAHD-GP-GLRARSKVLVTVLDENDNAPEVTVTSLT------SS 355
Query: 369 IFEGDPIDTFVALVRVQDKDSGLNGEIVCKLHGHGHFKLQKTYENNYLILTNATLDREKR 428
+ E T +AL V D DSG NG + C + + F L+KTY N Y +LT+ TLDRE+
Sbjct: 356 VQESSSPGTVIALFNVHDSDSGGNGLVTCSIPDNLPFTLEKTYGNYYRLLTHRTLDREEV 415
Query: 429 SEYSLTVIAEDRGTPSLSTVKHFTVQINDINDNPPHFQRSRYEFVISENNSPGAYITTVT 488
SEY++TV A D+GTP LST H ++Q+ DINDNPP F + Y I ENN GA I ++T
Sbjct: 416 SEYNITVTATDQGTPPLSTETHISLQVMDINDNPPTFPHASYSAYIPENNPRGASILSMT 475
Query: 489 ATDPDLGENGQVTYTILESFILGSSITTYVTIDPSNGAIYALRIFDHEEVSQITFVVEAR 548
A DPD G+N ++TY++ E G+ +++YV+I+ + G +YAL FD+E+ + ++ A
Sbjct: 476 AQDPDSGDNARITYSLAEDTFQGAPLSSYVSINSNTGILYALCSFDYEQFRDLQLLMTAS 535
Query: 549 DGGSPKQLVSNTTVVLTIIDENDNVPVVIGPAL--RNNTAEITIPKGAESGFHVTRIRAI 606
D G P L SN ++ L ++D+NDNVP ++ P +T P+ A+SG+ VT++ A+
Sbjct: 536 DSGDP-PLSSNVSLSLFVLDQNDNVPEILYPTFPTDGSTGVELAPRSADSGYLVTKVVAV 594
Query: 607 DRDSGVNAELSCAIVAGNEENIFIIDPRSCDIHTNVSMDSVPYTEWELSVIIQDKGNPQL 666
DRDSG NA LS +++ +E +F + + ++ T ++ + L V++QD G P L
Sbjct: 595 DRDSGQNAWLSYSLLKSSEPGLFAVGLHTGEVRTARALLDRDALKQRLVVVVQDHGQPPL 654
Query: 667 HTKVLLKCMIFEYAESVTSTAMTSVSQASLD---VSMIIIISLGAI-CAVLLVIMVLFAT 722
V L + + V + + A D +++ +++++ A+ C L + VL A
Sbjct: 655 SATVTLTVAVADSIPDVLADLGSLKPSADPDDSGLTLYLVVAVAAVSCVFLAFVTVLLAL 714
Query: 723 RCNREKK 729
+ R K
Sbjct: 715 KLRRWHK 721
>gi|11056026 protocadherin gamma subfamily A, 4 isoform 1 precursor
[Homo sapiens]
Length = 931
Score = 487 bits (1253), Expect = e-137
Identities = 269/727 (37%), Positives = 427/727 (58%), Gaps = 21/727 (2%)
Query: 9 HFRFVFALLIVSFNHDVLGKNLKYRIYEEQRVGSVIARLSEDVADVLLKLPNPSTVRFRA 68
H R + L++ ++ + + Y ++EEQ GSV+ +++D+ +L R
Sbjct: 10 HTRLLQICLLLGVLVEIRAEQILYSVFEEQEEGSVVGNIAKDLGLAPRELAERGV---RI 66
Query: 69 MQRGNSPLLVVNEDNGEISIGATIDREQLCQKNLNCSIEFDVITLPTEHLQLFHIEVEVL 128
+ RG + L +N +G + IDRE+LC ++ NC +++ T +++ +EVE++
Sbjct: 67 VSRGRTQLFALNPRSGTLVTAGRIDREELCDRSPNCVTNLEILLEDT--VKILRVEVEII 124
Query: 129 DINDNSPQFSRSLIPIEISESAAVGTRIPLDSAFDPDVGENSLHTYSLSANDFFNIEVRT 188
D+NDN P F I+++E+ G R PL AFDPDVG NSL Y L++N +F+++V++
Sbjct: 125 DVNDNPPSFGTEQREIKVAENENPGARFPLPEAFDPDVGVNSLQGYQLNSNGYFSLDVQS 184
Query: 189 RTDGAKYAELIVVRELDRELKSSYELQLTASDMGVPQRSGSSILKISISDSNDNSPAFEQ 248
DG KY EL++ R LDRE ++ + L LTA D G P RSG++ + I + D+NDN+P F Q
Sbjct: 185 GADGIKYPELVLERALDREEEAVHHLVLTAFDGGDPVRSGTARILIILVDTNDNAPVFTQ 244
Query: 249 QSYIIQLLENSPVGTLLLDLNATDPDEGANGKIVYSFSSHVSPKIMETFKIDSERGHLTL 308
Y + + EN PVGT LL + ATDPDEGANG + YSF V KI + F+++S G +T+
Sbjct: 245 PEYHVSVRENVPVGTRLLTVKATDPDEGANGDVTYSFRK-VRDKISQLFQLNSLSGDITI 303
Query: 309 FKQVDYEITKSYEIDVQAQDLGPNSIPAHCKIIIKVVDVNDNKPEININLMSPGKEEISY 368
+DYE + Y+IDV+A D GP + A K+++ V+D NDN PE+ + ++ S
Sbjct: 304 LGGLDYEDSGFYDIDVEAHD-GP-GLRARSKVLVTVLDENDNAPEVTVTSLT------SS 355
Query: 369 IFEGDPIDTFVALVRVQDKDSGLNGEIVCKLHGHGHFKLQKTYENNYLILTNATLDREKR 428
+ E T +AL V D DSG NG + C + + F L+KTY N Y +LT+ TLDRE+
Sbjct: 356 VQESSSPGTVIALFNVHDSDSGGNGLVTCSIPDNLPFTLEKTYGNYYRLLTHRTLDREEV 415
Query: 429 SEYSLTVIAEDRGTPSLSTVKHFTVQINDINDNPPHFQRSRYEFVISENNSPGAYITTVT 488
SEY++TV A D+GTP LST H ++Q+ DINDNPP F + Y I ENN GA I ++T
Sbjct: 416 SEYNITVTATDQGTPPLSTETHISLQVMDINDNPPTFPHASYSAYIPENNPRGASILSMT 475
Query: 489 ATDPDLGENGQVTYTILESFILGSSITTYVTIDPSNGAIYALRIFDHEEVSQITFVVEAR 548
A DPD G+N ++TY++ E G+ +++YV+I+ + G +YAL FD+E+ + ++ A
Sbjct: 476 AQDPDSGDNARITYSLAEDTFQGAPLSSYVSINSNTGILYALCSFDYEQFRDLQLLMTAS 535
Query: 549 DGGSPKQLVSNTTVVLTIIDENDNVPVVIGPAL--RNNTAEITIPKGAESGFHVTRIRAI 606
D G P L SN ++ L ++D+NDNVP ++ P +T P+ A+SG+ VT++ A+
Sbjct: 536 DSGDP-PLSSNVSLSLFVLDQNDNVPEILYPTFPTDGSTGVELAPRSADSGYLVTKVVAV 594
Query: 607 DRDSGVNAELSCAIVAGNEENIFIIDPRSCDIHTNVSMDSVPYTEWELSVIIQDKGNPQL 666
DRDSG NA LS +++ +E +F + + ++ T ++ + L V++QD G P L
Sbjct: 595 DRDSGQNAWLSYSLLKSSEPGLFAVGLHTGEVRTARALLDRDALKQRLVVVVQDHGQPPL 654
Query: 667 HTKVLLKCMIFEYAESVTSTAMTSVSQASLD---VSMIIIISLGAI-CAVLLVIMVLFAT 722
V L + + V + + A D +++ +++++ A+ C L + VL A
Sbjct: 655 SATVTLTVAVADSIPDVLADLGSLKPSADPDDSGLTLYLVVAVAAVSCVFLAFVTVLLAL 714
Query: 723 RCNREKK 729
+ R K
Sbjct: 715 KLRRWHK 721
>gi|8850232 protocadherin gamma subfamily A, 12 isoform 1 precursor
[Homo sapiens]
Length = 932
Score = 479 bits (1232), Expect = e-135
Identities = 268/706 (37%), Positives = 420/706 (59%), Gaps = 21/706 (2%)
Query: 30 LKYRIYEEQRVGSVIARLSEDVADVLLKLPNPSTVRFRAMQRGNSPLLVVNEDNGEISIG 89
++Y + EE GS + +S D+ +L R + RG + L +N +G +
Sbjct: 31 IRYSVPEELEKGSRVGDISRDLGLEPRELAERGV---RIIPRGRTQLFALNPRSGSLVTA 87
Query: 90 ATIDREQLCQKNLNCSIEFDVITLPTEHLQLFHIEVEVLDINDNSPQFSRSLIPIEISES 149
IDRE+LC + C + D+ L + ++++ +EVEV DINDN+P F S + I+ISE+
Sbjct: 88 GRIDREELCMGAIKCQLNLDI--LMEDKVKIYGVEVEVRDINDNAPYFRESELEIKISEN 145
Query: 150 AAVGTRIPLDSAFDPDVGENSLHTYSLSANDFFNIEVRTRTDGAKYAELIVVRELDRELK 209
AA R PL A+DPD+G+NSL +Y LS N F++ V+ DG+KY EL++ R LDRE K
Sbjct: 146 AATEMRFPLPHAWDPDIGKNSLQSYELSPNTHFSLIVQNGADGSKYPELVLKRALDREEK 205
Query: 210 SSYELQLTASDMGVPQRSGSSILKISISDSNDNSPAFEQQSYIIQLLENSPVGTLLLDLN 269
+++ L LTASD G P R+G++ +++ + D+NDN+PAF Q Y + EN +GT LL +N
Sbjct: 206 AAHHLVLTASDGGDPVRTGTARIRVMVLDANDNAPAFAQPEYRASVPENLALGTQLLVVN 265
Query: 270 ATDPDEGANGKIVYSFSSHVSPKIMETFKIDSERGHLTLFKQVDYEITKSYEIDVQAQDL 329
ATDPDEG N ++ YSF +V K + FK+D G ++ ++D+E + Y+++VQA D
Sbjct: 266 ATDPDEGVNAEVRYSF-RYVDDKAAQVFKLDCNSGTISTIGELDHEESGFYQMEVQAMDN 324
Query: 330 GPNSIPAHCKIIIKVVDVNDNKPEININLMSPGKEEISYIFEGDPIDTFVALVRVQDKDS 389
S A K++I V+DVNDN PE+ + ++ S + E P T +AL+ V D+DS
Sbjct: 325 AGYS--ARAKVLITVLDVNDNAPEVVLTSLA------SSVPENSPRGTLIALLNVNDQDS 376
Query: 390 GLNGEIVCKLHGHGHFKLQKTYENNYLILTNATLDREKRSEYSLTVIAEDRGTPSLSTVK 449
NG+++C + G+ FKL+K+Y N Y ++T+ LDRE+ Y++TV A DRGTP LST
Sbjct: 377 EENGQVICFIQGNLPFKLEKSYGNYYSLVTDIVLDREQVPSYNITVTATDRGTPPLSTET 436
Query: 450 HFTVQINDINDNPPHFQRSRYEFVISENNSPGAYITTVTATDPDLGENGQVTYTILESFI 509
H ++ + D NDNPP F ++ Y I ENN G + +VTA DPD EN Q+TY++ E+ I
Sbjct: 437 HISLNVADTNDNPPVFPQASYSAYIPENNPRGVSLVSVTAHDPDCEENAQITYSLAENTI 496
Query: 510 LGSSITTYVTIDPSNGAIYALRIFDHEEVSQITFVVEARDGGSPKQLVSNTTVVLTIIDE 569
G+S+++YV+I+ G +YAL FD+E+ + V ARD G P L SN ++ L ++D+
Sbjct: 497 QGASLSSYVSINSDTGVLYALSSFDYEQFRDLQVKVMARDNGHP-PLSSNVSLSLFVLDQ 555
Query: 570 NDNVPVVIGPAL--RNNTAEITIPKGAESGFHVTRIRAIDRDSGVNAELSCAIVAGNEEN 627
NDN P ++ PAL +T P+ AE G+ VT++ A+DRDSG NA LS ++ +E
Sbjct: 556 NDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLLKASEPG 615
Query: 628 IFIIDPRSCDIHTNVSMDSVPYTEWELSVIIQDKGNPQLHTKVLLKCMIFEYAESVTSTA 687
+F + + ++ T ++ + L V +QD G P L V L + + V +
Sbjct: 616 LFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSIPQVLADL 675
Query: 688 MTSVSQA---SLDVSMIIIISLGAI-CAVLLVIMVLFATRCNREKK 729
+ S A + D+++ +++++ A+ C L +++L A R R K
Sbjct: 676 GSLESPANSETSDLTLYLVVAVAAVSCVFLAFVILLLALRLRRWHK 721
>gi|14196457 protocadherin gamma subfamily A, 12 isoform 2 precursor
[Homo sapiens]
Length = 820
Score = 479 bits (1232), Expect = e-135
Identities = 268/706 (37%), Positives = 420/706 (59%), Gaps = 21/706 (2%)
Query: 30 LKYRIYEEQRVGSVIARLSEDVADVLLKLPNPSTVRFRAMQRGNSPLLVVNEDNGEISIG 89
++Y + EE GS + +S D+ +L R + RG + L +N +G +
Sbjct: 31 IRYSVPEELEKGSRVGDISRDLGLEPRELAERGV---RIIPRGRTQLFALNPRSGSLVTA 87
Query: 90 ATIDREQLCQKNLNCSIEFDVITLPTEHLQLFHIEVEVLDINDNSPQFSRSLIPIEISES 149
IDRE+LC + C + D+ L + ++++ +EVEV DINDN+P F S + I+ISE+
Sbjct: 88 GRIDREELCMGAIKCQLNLDI--LMEDKVKIYGVEVEVRDINDNAPYFRESELEIKISEN 145
Query: 150 AAVGTRIPLDSAFDPDVGENSLHTYSLSANDFFNIEVRTRTDGAKYAELIVVRELDRELK 209
AA R PL A+DPD+G+NSL +Y LS N F++ V+ DG+KY EL++ R LDRE K
Sbjct: 146 AATEMRFPLPHAWDPDIGKNSLQSYELSPNTHFSLIVQNGADGSKYPELVLKRALDREEK 205
Query: 210 SSYELQLTASDMGVPQRSGSSILKISISDSNDNSPAFEQQSYIIQLLENSPVGTLLLDLN 269
+++ L LTASD G P R+G++ +++ + D+NDN+PAF Q Y + EN +GT LL +N
Sbjct: 206 AAHHLVLTASDGGDPVRTGTARIRVMVLDANDNAPAFAQPEYRASVPENLALGTQLLVVN 265
Query: 270 ATDPDEGANGKIVYSFSSHVSPKIMETFKIDSERGHLTLFKQVDYEITKSYEIDVQAQDL 329
ATDPDEG N ++ YSF +V K + FK+D G ++ ++D+E + Y+++VQA D
Sbjct: 266 ATDPDEGVNAEVRYSF-RYVDDKAAQVFKLDCNSGTISTIGELDHEESGFYQMEVQAMDN 324
Query: 330 GPNSIPAHCKIIIKVVDVNDNKPEININLMSPGKEEISYIFEGDPIDTFVALVRVQDKDS 389
S A K++I V+DVNDN PE+ + ++ S + E P T +AL+ V D+DS
Sbjct: 325 AGYS--ARAKVLITVLDVNDNAPEVVLTSLA------SSVPENSPRGTLIALLNVNDQDS 376
Query: 390 GLNGEIVCKLHGHGHFKLQKTYENNYLILTNATLDREKRSEYSLTVIAEDRGTPSLSTVK 449
NG+++C + G+ FKL+K+Y N Y ++T+ LDRE+ Y++TV A DRGTP LST
Sbjct: 377 EENGQVICFIQGNLPFKLEKSYGNYYSLVTDIVLDREQVPSYNITVTATDRGTPPLSTET 436
Query: 450 HFTVQINDINDNPPHFQRSRYEFVISENNSPGAYITTVTATDPDLGENGQVTYTILESFI 509
H ++ + D NDNPP F ++ Y I ENN G + +VTA DPD EN Q+TY++ E+ I
Sbjct: 437 HISLNVADTNDNPPVFPQASYSAYIPENNPRGVSLVSVTAHDPDCEENAQITYSLAENTI 496
Query: 510 LGSSITTYVTIDPSNGAIYALRIFDHEEVSQITFVVEARDGGSPKQLVSNTTVVLTIIDE 569
G+S+++YV+I+ G +YAL FD+E+ + V ARD G P L SN ++ L ++D+
Sbjct: 497 QGASLSSYVSINSDTGVLYALSSFDYEQFRDLQVKVMARDNGHP-PLSSNVSLSLFVLDQ 555
Query: 570 NDNVPVVIGPAL--RNNTAEITIPKGAESGFHVTRIRAIDRDSGVNAELSCAIVAGNEEN 627
NDN P ++ PAL +T P+ AE G+ VT++ A+DRDSG NA LS ++ +E
Sbjct: 556 NDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLLKASEPG 615
Query: 628 IFIIDPRSCDIHTNVSMDSVPYTEWELSVIIQDKGNPQLHTKVLLKCMIFEYAESVTSTA 687
+F + + ++ T ++ + L V +QD G P L V L + + V +
Sbjct: 616 LFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSIPQVLADL 675
Query: 688 MTSVSQA---SLDVSMIIIISLGAI-CAVLLVIMVLFATRCNREKK 729
+ S A + D+++ +++++ A+ C L +++L A R R K
Sbjct: 676 GSLESPANSETSDLTLYLVVAVAAVSCVFLAFVILLLALRLRRWHK 721
>gi|11128041 protocadherin gamma subfamily A, 10 isoform 1 precursor
[Homo sapiens]
Length = 936
Score = 478 bits (1231), Expect = e-134
Identities = 268/709 (37%), Positives = 419/709 (59%), Gaps = 23/709 (3%)
Query: 28 KNLKYRIYEEQRVGSVIARLSEDVADVLLKLPNPSTVRFRAMQRGNSPLLVVNEDNGEIS 87
+ + Y I EE GS + +S+D+ +L R + RG + L +N +G +
Sbjct: 33 RQISYSIPEELEKGSFVGNISKDLGLAPRELAERGV---RIVSRGRTQLFSLNPRSGSLI 89
Query: 88 IGATIDREQLCQKNLNCSIEFDVITLPTEHLQLFHIEVEVLDINDNSPQFSRSLIPIEIS 147
IDRE+LC ++ C + F+++ + ++LF IE+EV DINDN+P+F + ++I+
Sbjct: 90 TAGRIDREELCAQSARCVVSFNILV--EDRVKLFGIEIEVTDINDNAPKFQAENLDVKIN 147
Query: 148 ESAAVGTRIPLDSAFDPDVGENSLHTYSLSANDFFNIEVRTRTDGAKYAELIVVRELDRE 207
E+ A G R PL A DPDVG NSL +Y LS N F++ V++R +G KY EL++ LDRE
Sbjct: 148 ENVAAGMRFPLPEAIDPDVGVNSLQSYQLSPNKHFSLRVQSRANGVKYPELVLEHSLDRE 207
Query: 208 LKSSYELQLTASDMGVPQRSGSSILKISISDSNDNSPAFEQQSYIIQLLENSPVGTLLLD 267
++ + L LTASD G P RSG+ ++ +++ D+NDN+P F Y + + EN PVGT LL
Sbjct: 208 EEAIHHLVLTASDGGDPLRSGTVLVSVTVFDANDNAPVFTLPEYRVSVPENLPVGTQLLT 267
Query: 268 LNATDPDEGANGKIVYSFSSHVSPKIMETFKIDSERGHLTLFKQVDYEITKSYEIDVQAQ 327
+ ATD DEGANG++ YSF ++++ F+++ G + + + +DYE T YEI++QA+
Sbjct: 268 VTATDRDEGANGEVTYSFRKLPDTQLLK-FQLNKYTGEIKISENLDYEETGFYEIEIQAE 326
Query: 328 DLGPNSIPAHCKIIIKVVDVNDNKPEINI-NLMSPGKEEISYIFEGDPIDTFVALVRVQD 386
D G + A K++I V DVNDN PE+ I +L SP + E P+ T VAL+ V D
Sbjct: 327 DGG--AYLATAKVLITVEDVNDNSPELTITSLFSP-------VTEDSPLGTVVALLNVHD 377
Query: 387 KDSGLNGEIVCKLHGHGHFKLQKTYENNYLILTNATLDREKRSEYSLTVIAEDRGTPSLS 446
DS NG++ C + + FKL+K+ ++ Y ++ + LDRE+ S Y++TV A D G+P LS
Sbjct: 378 LDSEQNGQVTCSILAYLPFKLEKSIDSYYRLVIHRALDREQVSSYNITVTATDGGSPPLS 437
Query: 447 TVKHFTVQINDINDNPPHFQRSRYEFVISENNSPGAYITTVTATDPDLGENGQVTYTILE 506
T HF +Q+ DINDNPP F + Y I ENN+ GA I +VTA DPD EN Q+ Y++ E
Sbjct: 438 TEAHFMLQVADINDNPPTFSQVSYFTYIPENNARGASIFSVTALDPDSKENAQIIYSLAE 497
Query: 507 SFILGSSITTYVTIDPSNGAIYALRIFDHEEVSQITFVVEARDGGSPKQLVSNTTVVLTI 566
I G +++Y++I+ G +YALR FD+E+ ++ V A D G P L SN ++ L +
Sbjct: 498 DTIQGVPLSSYISINSDTGVLYALRSFDYEQFHELQMQVTASDSGDP-PLSSNVSLSLFV 556
Query: 567 IDENDNVPVVIGPAL--RNNTAEITIPKGAESGFHVTRIRAIDRDSGVNAELSCAIVAGN 624
+D+NDN P ++ PAL +T P+ AE G+ VT++ A+DRDSG NA LS ++ +
Sbjct: 557 LDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLLKAS 616
Query: 625 EENIFIIDPRSCDIHTNVSMDSVPYTEWELSVIIQDKGNPQLHTKVLLKCMIFEYAESVT 684
E +F + + ++ T ++ + L V +QD G P L V L + + V
Sbjct: 617 EPGLFAVGEHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSIPQVL 676
Query: 685 STAMTSVSQA---SLDVSMIIIISLGAI-CAVLLVIMVLFATRCNREKK 729
+ + S A + D+++ +++++ A+ C L ++VL A R R K
Sbjct: 677 ADLGSFESPANSETSDLTLYLVVAVAAVSCVFLAFVIVLLAHRLRRWHK 725
>gi|14196448 protocadherin gamma subfamily A, 10 isoform 2 precursor
[Homo sapiens]
Length = 850
Score = 478 bits (1231), Expect = e-134
Identities = 268/709 (37%), Positives = 419/709 (59%), Gaps = 23/709 (3%)
Query: 28 KNLKYRIYEEQRVGSVIARLSEDVADVLLKLPNPSTVRFRAMQRGNSPLLVVNEDNGEIS 87
+ + Y I EE GS + +S+D+ +L R + RG + L +N +G +
Sbjct: 33 RQISYSIPEELEKGSFVGNISKDLGLAPRELAERGV---RIVSRGRTQLFSLNPRSGSLI 89
Query: 88 IGATIDREQLCQKNLNCSIEFDVITLPTEHLQLFHIEVEVLDINDNSPQFSRSLIPIEIS 147
IDRE+LC ++ C + F+++ + ++LF IE+EV DINDN+P+F + ++I+
Sbjct: 90 TAGRIDREELCAQSARCVVSFNILV--EDRVKLFGIEIEVTDINDNAPKFQAENLDVKIN 147
Query: 148 ESAAVGTRIPLDSAFDPDVGENSLHTYSLSANDFFNIEVRTRTDGAKYAELIVVRELDRE 207
E+ A G R PL A DPDVG NSL +Y LS N F++ V++R +G KY EL++ LDRE
Sbjct: 148 ENVAAGMRFPLPEAIDPDVGVNSLQSYQLSPNKHFSLRVQSRANGVKYPELVLEHSLDRE 207
Query: 208 LKSSYELQLTASDMGVPQRSGSSILKISISDSNDNSPAFEQQSYIIQLLENSPVGTLLLD 267
++ + L LTASD G P RSG+ ++ +++ D+NDN+P F Y + + EN PVGT LL
Sbjct: 208 EEAIHHLVLTASDGGDPLRSGTVLVSVTVFDANDNAPVFTLPEYRVSVPENLPVGTQLLT 267
Query: 268 LNATDPDEGANGKIVYSFSSHVSPKIMETFKIDSERGHLTLFKQVDYEITKSYEIDVQAQ 327
+ ATD DEGANG++ YSF ++++ F+++ G + + + +DYE T YEI++QA+
Sbjct: 268 VTATDRDEGANGEVTYSFRKLPDTQLLK-FQLNKYTGEIKISENLDYEETGFYEIEIQAE 326
Query: 328 DLGPNSIPAHCKIIIKVVDVNDNKPEINI-NLMSPGKEEISYIFEGDPIDTFVALVRVQD 386
D G + A K++I V DVNDN PE+ I +L SP + E P+ T VAL+ V D
Sbjct: 327 DGG--AYLATAKVLITVEDVNDNSPELTITSLFSP-------VTEDSPLGTVVALLNVHD 377
Query: 387 KDSGLNGEIVCKLHGHGHFKLQKTYENNYLILTNATLDREKRSEYSLTVIAEDRGTPSLS 446
DS NG++ C + + FKL+K+ ++ Y ++ + LDRE+ S Y++TV A D G+P LS
Sbjct: 378 LDSEQNGQVTCSILAYLPFKLEKSIDSYYRLVIHRALDREQVSSYNITVTATDGGSPPLS 437
Query: 447 TVKHFTVQINDINDNPPHFQRSRYEFVISENNSPGAYITTVTATDPDLGENGQVTYTILE 506
T HF +Q+ DINDNPP F + Y I ENN+ GA I +VTA DPD EN Q+ Y++ E
Sbjct: 438 TEAHFMLQVADINDNPPTFSQVSYFTYIPENNARGASIFSVTALDPDSKENAQIIYSLAE 497
Query: 507 SFILGSSITTYVTIDPSNGAIYALRIFDHEEVSQITFVVEARDGGSPKQLVSNTTVVLTI 566
I G +++Y++I+ G +YALR FD+E+ ++ V A D G P L SN ++ L +
Sbjct: 498 DTIQGVPLSSYISINSDTGVLYALRSFDYEQFHELQMQVTASDSGDP-PLSSNVSLSLFV 556
Query: 567 IDENDNVPVVIGPAL--RNNTAEITIPKGAESGFHVTRIRAIDRDSGVNAELSCAIVAGN 624
+D+NDN P ++ PAL +T P+ AE G+ VT++ A+DRDSG NA LS ++ +
Sbjct: 557 LDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLLKAS 616
Query: 625 EENIFIIDPRSCDIHTNVSMDSVPYTEWELSVIIQDKGNPQLHTKVLLKCMIFEYAESVT 684
E +F + + ++ T ++ + L V +QD G P L V L + + V
Sbjct: 617 EPGLFAVGEHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSIPQVL 676
Query: 685 STAMTSVSQA---SLDVSMIIIISLGAI-CAVLLVIMVLFATRCNREKK 729
+ + S A + D+++ +++++ A+ C L ++VL A R R K
Sbjct: 677 ADLGSFESPANSETSDLTLYLVVAVAAVSCVFLAFVIVLLAHRLRRWHK 725
>gi|9256586 protocadherin alpha 3 isoform 1 precursor [Homo sapiens]
Length = 950
Score = 473 bits (1218), Expect = e-133
Identities = 265/723 (36%), Positives = 428/723 (59%), Gaps = 23/723 (3%)
Query: 13 VFALLIVSFNHDVLGKNLKYRIYEEQRVGSVIARLSEDVADVLLKLPNPSTVRFRAMQRG 72
+ +LL+++ + +V L Y + EE + G+ + R+++D+ L+L FR +
Sbjct: 15 LLSLLLLAAS-EVGSGQLHYSVSEEAKHGTFVGRIAQDLG---LELAELVPRLFRVASKR 70
Query: 73 NSPLLVVNEDNGEISIGATIDREQLCQKNLNCSIEFDVITLPTEHLQLFHIEVEVLDIND 132
+ LL VN NG + + + IDRE+LC ++ CSI +VI LQ+FH+EVEV DIND
Sbjct: 71 HGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIV--DRPLQVFHVEVEVKDIND 128
Query: 133 NSPQFSRSLIPIEISESAAVGTRIPLDSAFDPDVGENSLHTYSLSANDFFNIEVRTRTDG 192
N+P F ++ + ISES G+R L+ A D D+G NSL TYSL + ++F ++V+ +
Sbjct: 129 NAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTLDVKRNDEE 188
Query: 193 AKYAELIVVRELDRELKSSYELQLTASDMGVPQRSGSSILKISISDSNDNSPAFEQQSYI 252
K L++ + L+RE + L +TA D G P+ +G++ LKI++ D NDN+PAFE+ Y
Sbjct: 189 IKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAPAFERTIYK 248
Query: 253 IQLLENSPVGTLLLDLNATDPDEGANGKIVYSFSSHVSPKIMETFKIDSERGHLTLFKQV 312
++LLEN+P GTL++ +NATD DEG N I YSF++ +S I+ F +D G +++ +
Sbjct: 249 VRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNGQISVKGNI 308
Query: 313 DYEITKSYEIDVQAQDLGPNSIPAHCKIIIKVVDVNDNKPEININLMSPGKEEISYIFEG 372
D+E +KSYEI V+A D G + HC +++++VD+NDN PE+ I +S + E
Sbjct: 309 DFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLS------LPVLED 362
Query: 373 DPIDTFVALVRVQDKDSGLNGEIVCKLHGHGHFKLQKTYENNYLILTNATLDREKRSEYS 432
P+ T +AL+ V D+DSG+NG++ C L H FKL T++N Y ++ ++ LDRE S Y
Sbjct: 363 SPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSAYE 422
Query: 433 LTVIAEDRGTPSLSTVKHFTVQINDINDNPPHFQRSRYEFVISENNSPGAYITTVTATDP 492
L V A D G+PSL +V++ D+NDN P F +S Y + ENN PG +I TV+A D
Sbjct: 423 LVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSARDA 482
Query: 493 DLGENGQVTYTILESFILGSSITTYVTIDPSNGAIYALRIFDHEEVSQITFVVEARDGGS 552
D EN V+Y+++E + ++++YV++ +G +YAL+ DHEE+ + F V ARD G
Sbjct: 483 DAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGV 542
Query: 553 PKQLVSNTTVVLTIIDENDNVPVVIGPALRNNTAEIT--IPKGAESGFHVTRIRAIDRDS 610
P L SN T+ + ++DENDN P ++ P + ++ +P+ +G V ++RA+D DS
Sbjct: 543 P-PLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDADS 601
Query: 611 GVNAELSCAIV--AGNEENIFIIDPRSCDIHTNVSMDSVPYTEWELSVIIQDKGNPQLHT 668
G NA LS + G F + + +I T ++D V L V+++D G P L
Sbjct: 602 GYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLTA 661
Query: 669 KVLLKCMIFE-----YAESVTSTAMTSVSQASLDVSMIIIISLGAICAVLLVIMVLF-AT 722
+ + E A S S T A +DV++ +I+++ A+ ++L++ ++L+ A
Sbjct: 662 TATVLVSLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTAL 721
Query: 723 RCN 725
RC+
Sbjct: 722 RCS 724
>gi|14165410 protocadherin alpha 3 isoform 2 precursor [Homo
sapiens]
Length = 824
Score = 473 bits (1218), Expect = e-133
Identities = 265/723 (36%), Positives = 428/723 (59%), Gaps = 23/723 (3%)
Query: 13 VFALLIVSFNHDVLGKNLKYRIYEEQRVGSVIARLSEDVADVLLKLPNPSTVRFRAMQRG 72
+ +LL+++ + +V L Y + EE + G+ + R+++D+ L+L FR +
Sbjct: 15 LLSLLLLAAS-EVGSGQLHYSVSEEAKHGTFVGRIAQDLG---LELAELVPRLFRVASKR 70
Query: 73 NSPLLVVNEDNGEISIGATIDREQLCQKNLNCSIEFDVITLPTEHLQLFHIEVEVLDIND 132
+ LL VN NG + + + IDRE+LC ++ CSI +VI LQ+FH+EVEV DIND
Sbjct: 71 HGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIV--DRPLQVFHVEVEVKDIND 128
Query: 133 NSPQFSRSLIPIEISESAAVGTRIPLDSAFDPDVGENSLHTYSLSANDFFNIEVRTRTDG 192
N+P F ++ + ISES G+R L+ A D D+G NSL TYSL + ++F ++V+ +
Sbjct: 129 NAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTLDVKRNDEE 188
Query: 193 AKYAELIVVRELDRELKSSYELQLTASDMGVPQRSGSSILKISISDSNDNSPAFEQQSYI 252
K L++ + L+RE + L +TA D G P+ +G++ LKI++ D NDN+PAFE+ Y
Sbjct: 189 IKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAPAFERTIYK 248
Query: 253 IQLLENSPVGTLLLDLNATDPDEGANGKIVYSFSSHVSPKIMETFKIDSERGHLTLFKQV 312
++LLEN+P GTL++ +NATD DEG N I YSF++ +S I+ F +D G +++ +
Sbjct: 249 VRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNGQISVKGNI 308
Query: 313 DYEITKSYEIDVQAQDLGPNSIPAHCKIIIKVVDVNDNKPEININLMSPGKEEISYIFEG 372
D+E +KSYEI V+A D G + HC +++++VD+NDN PE+ I +S + E
Sbjct: 309 DFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLS------LPVLED 362
Query: 373 DPIDTFVALVRVQDKDSGLNGEIVCKLHGHGHFKLQKTYENNYLILTNATLDREKRSEYS 432
P+ T +AL+ V D+DSG+NG++ C L H FKL T++N Y ++ ++ LDRE S Y
Sbjct: 363 SPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSAYE 422
Query: 433 LTVIAEDRGTPSLSTVKHFTVQINDINDNPPHFQRSRYEFVISENNSPGAYITTVTATDP 492
L V A D G+PSL +V++ D+NDN P F +S Y + ENN PG +I TV+A D
Sbjct: 423 LVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSARDA 482
Query: 493 DLGENGQVTYTILESFILGSSITTYVTIDPSNGAIYALRIFDHEEVSQITFVVEARDGGS 552
D EN V+Y+++E + ++++YV++ +G +YAL+ DHEE+ + F V ARD G
Sbjct: 483 DAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGV 542
Query: 553 PKQLVSNTTVVLTIIDENDNVPVVIGPALRNNTAEIT--IPKGAESGFHVTRIRAIDRDS 610
P L SN T+ + ++DENDN P ++ P + ++ +P+ +G V ++RA+D DS
Sbjct: 543 P-PLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDADS 601
Query: 611 GVNAELSCAIV--AGNEENIFIIDPRSCDIHTNVSMDSVPYTEWELSVIIQDKGNPQLHT 668
G NA LS + G F + + +I T ++D V L V+++D G P L
Sbjct: 602 GYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLTA 661
Query: 669 KVLLKCMIFE-----YAESVTSTAMTSVSQASLDVSMIIIISLGAICAVLLVIMVLF-AT 722
+ + E A S S T A +DV++ +I+++ A+ ++L++ ++L+ A
Sbjct: 662 TATVLVSLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTAL 721
Query: 723 RCN 725
RC+
Sbjct: 722 RCS 724
>gi|14165400 protocadherin alpha 1 isoform 2 precursor [Homo
sapiens]
Length = 807
Score = 471 bits (1213), Expect = e-132
Identities = 267/707 (37%), Positives = 416/707 (58%), Gaps = 24/707 (3%)
Query: 30 LKYRIYEEQRVGSVIARLSEDVADVLLKLPNPSTVRFRAMQRGNSPLLVVNEDNGEISIG 89
L Y I EE + G+ + R+++D+ L+L FR + + LL VN NG + +
Sbjct: 31 LHYSIPEEAKHGTFVGRVAQDLG---LELAELVPRLFRVASKTHRDLLEVNLQNGILFVN 87
Query: 90 ATIDREQLCQKNLNCSIEFDVITLPTEHLQLFHIEVEVLDINDNSPQFSRSLIPIEISES 149
+ IDRE+LCQ + CSI ++I LQ+FH+EV+V DINDN P F I I ES
Sbjct: 88 SRIDREELCQWSAECSIHLELIA--DRPLQVFHVEVKVKDINDNPPVFRGREQIIFIPES 145
Query: 150 AAVGTRIPLDSAFDPDVGENSLHTYSLSANDFFNIEVRTRTDGAKYAELIVVRELDRELK 209
+ +R P++ A D D+G N+L TY+LS +D+F+++V + +K L + + LDRE
Sbjct: 146 RLLNSRFPIEGAADADIGANALLTYTLSPSDYFSLDVEASDELSKSLWLELRKYLDREET 205
Query: 210 SSYELQLTASDMGVPQRSGSSILKISISDSNDNSPAFEQQSYIIQLLENSPVGTLLLDLN 269
L LTA+D G P+ G+ L I++ D NDN+P F+Q Y + LLE + GTL+ LN
Sbjct: 206 PELHLLLTATDGGKPELQGTVELLITVLDVNDNAPLFDQAVYRVHLLETTANGTLVTTLN 265
Query: 270 ATDPDEGANGKIVYSFSSHVSPKIMETFKIDSERGHLTLFKQVDYEITKSYEIDVQAQDL 329
A+D DEG NG++V+SF S +S I E FK+DS G + L ++DYE TKSYEI V+A D
Sbjct: 266 ASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSGEIRLIDKLDYEETKSYEIQVKAVDK 325
Query: 330 GPNSIPAHCKIIIKVVDVNDNKPEINI-NLMSPGKEEISYIFEGDPIDTFVALVRVQDKD 388
G + HCK+++KV+DVNDN PE+ + +L P +E+ P+ T +AL+ V D+D
Sbjct: 326 GSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIREDA-------PLSTVIALITVSDRD 378
Query: 389 SGLNGEIVCKLHGHGHFKLQKTYENNYLILTNATLDREKRSEYSLTVIAEDRGTPSLSTV 448
SG NG++ C L H FKL T++N Y ++ ++ LDRE S Y L V A D G+PSL
Sbjct: 379 SGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSVYELVVTARDGGSPSLWAT 438
Query: 449 KHFTVQINDINDNPPHFQRSRYEFVISENNSPGAYITTVTATDPDLGENGQVTYTILESF 508
+V++ D+NDN P F + Y + ENN PG +I TV+A D D EN V+Y+++E
Sbjct: 439 ARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVERR 498
Query: 509 ILGSSITTYVTIDPSNGAIYALRIFDHEEVSQITFVVEARDGGSPKQLVSNTTVVLTIID 568
+ +++ YV++ +G +YAL+ DHEE+ + F V ARD G P L SN T+ + ++D
Sbjct: 499 VGERALSNYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVP-PLGSNVTLQVFVLD 557
Query: 569 ENDNVPVVIGPALRNNTAEIT--IPKGAESGFHVTRIRAIDRDSGVNAELSCAI--VAGN 624
ENDN P ++ P + ++ +P+ +G V ++RA+D DSG NA LS + AG
Sbjct: 558 ENDNAPALLAPRVGGTIGAVSELVPRLVGAGHVVAKVRAVDADSGYNAWLSYELQPAAGG 617
Query: 625 EENIFIIDPRSCDIHTNVSMDSVPYTEWELSVIIQDKGNPQLHTKVLLKCMIFEYAESVT 684
F + + +I T +D + + L V+++D G P L + + E ++
Sbjct: 618 ARIPFRVGLYTGEISTTRVLDEADLSRYRLLVLVKDHGEPALTATATVLVSLVESGQAPK 677
Query: 685 STAMTSVSQAS-----LDVSMIIIISLGAICAVLLVIMVLF-ATRCN 725
+++ SV A +DV++ +II++ A+ ++L++ ++L+ A RC+
Sbjct: 678 ASSRASVGVAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCS 724
>gi|9256582 protocadherin alpha 1 isoform 1 precursor [Homo sapiens]
Length = 950
Score = 471 bits (1213), Expect = e-132
Identities = 267/707 (37%), Positives = 416/707 (58%), Gaps = 24/707 (3%)
Query: 30 LKYRIYEEQRVGSVIARLSEDVADVLLKLPNPSTVRFRAMQRGNSPLLVVNEDNGEISIG 89
L Y I EE + G+ + R+++D+ L+L FR + + LL VN NG + +
Sbjct: 31 LHYSIPEEAKHGTFVGRVAQDLG---LELAELVPRLFRVASKTHRDLLEVNLQNGILFVN 87
Query: 90 ATIDREQLCQKNLNCSIEFDVITLPTEHLQLFHIEVEVLDINDNSPQFSRSLIPIEISES 149
+ IDRE+LCQ + CSI ++I LQ+FH+EV+V DINDN P F I I ES
Sbjct: 88 SRIDREELCQWSAECSIHLELIA--DRPLQVFHVEVKVKDINDNPPVFRGREQIIFIPES 145
Query: 150 AAVGTRIPLDSAFDPDVGENSLHTYSLSANDFFNIEVRTRTDGAKYAELIVVRELDRELK 209
+ +R P++ A D D+G N+L TY+LS +D+F+++V + +K L + + LDRE
Sbjct: 146 RLLNSRFPIEGAADADIGANALLTYTLSPSDYFSLDVEASDELSKSLWLELRKYLDREET 205
Query: 210 SSYELQLTASDMGVPQRSGSSILKISISDSNDNSPAFEQQSYIIQLLENSPVGTLLLDLN 269
L LTA+D G P+ G+ L I++ D NDN+P F+Q Y + LLE + GTL+ LN
Sbjct: 206 PELHLLLTATDGGKPELQGTVELLITVLDVNDNAPLFDQAVYRVHLLETTANGTLVTTLN 265
Query: 270 ATDPDEGANGKIVYSFSSHVSPKIMETFKIDSERGHLTLFKQVDYEITKSYEIDVQAQDL 329
A+D DEG NG++V+SF S +S I E FK+DS G + L ++DYE TKSYEI V+A D
Sbjct: 266 ASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSGEIRLIDKLDYEETKSYEIQVKAVDK 325
Query: 330 GPNSIPAHCKIIIKVVDVNDNKPEINI-NLMSPGKEEISYIFEGDPIDTFVALVRVQDKD 388
G + HCK+++KV+DVNDN PE+ + +L P +E+ P+ T +AL+ V D+D
Sbjct: 326 GSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIREDA-------PLSTVIALITVSDRD 378
Query: 389 SGLNGEIVCKLHGHGHFKLQKTYENNYLILTNATLDREKRSEYSLTVIAEDRGTPSLSTV 448
SG NG++ C L H FKL T++N Y ++ ++ LDRE S Y L V A D G+PSL
Sbjct: 379 SGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSVYELVVTARDGGSPSLWAT 438
Query: 449 KHFTVQINDINDNPPHFQRSRYEFVISENNSPGAYITTVTATDPDLGENGQVTYTILESF 508
+V++ D+NDN P F + Y + ENN PG +I TV+A D D EN V+Y+++E
Sbjct: 439 ARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVERR 498
Query: 509 ILGSSITTYVTIDPSNGAIYALRIFDHEEVSQITFVVEARDGGSPKQLVSNTTVVLTIID 568
+ +++ YV++ +G +YAL+ DHEE+ + F V ARD G P L SN T+ + ++D
Sbjct: 499 VGERALSNYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVP-PLGSNVTLQVFVLD 557
Query: 569 ENDNVPVVIGPALRNNTAEIT--IPKGAESGFHVTRIRAIDRDSGVNAELSCAI--VAGN 624
ENDN P ++ P + ++ +P+ +G V ++RA+D DSG NA LS + AG
Sbjct: 558 ENDNAPALLAPRVGGTIGAVSELVPRLVGAGHVVAKVRAVDADSGYNAWLSYELQPAAGG 617
Query: 625 EENIFIIDPRSCDIHTNVSMDSVPYTEWELSVIIQDKGNPQLHTKVLLKCMIFEYAESVT 684
F + + +I T +D + + L V+++D G P L + + E ++
Sbjct: 618 ARIPFRVGLYTGEISTTRVLDEADLSRYRLLVLVKDHGEPALTATATVLVSLVESGQAPK 677
Query: 685 STAMTSVSQAS-----LDVSMIIIISLGAICAVLLVIMVLF-ATRCN 725
+++ SV A +DV++ +II++ A+ ++L++ ++L+ A RC+
Sbjct: 678 ASSRASVGVAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCS 724
>gi|14196471 protocadherin gamma subfamily A, 5 isoform 2 precursor
[Homo sapiens]
Length = 813
Score = 468 bits (1203), Expect = e-131
Identities = 257/706 (36%), Positives = 422/706 (59%), Gaps = 21/706 (2%)
Query: 30 LKYRIYEEQRVGSVIARLSEDVADVLLKLPNPSTVRFRAMQRGNSPLLVVNEDNGEISIG 89
++Y + EE GS + +++D+ L+ + R + RG + L +N +G +
Sbjct: 31 IRYSMPEELDKGSFVGNIAKDLG---LEPQELAERGVRIVSRGRTQLFALNPRSGSLVTA 87
Query: 90 ATIDREQLCQKNLNCSIEFDVITLPTEHLQLFHIEVEVLDINDNSPQFSRSLIPIEISES 149
IDRE+LC ++ C + F+++ ++++ +EVE++DINDN P+F + ++++E+
Sbjct: 88 GRIDREELCAQSPLCVVNFNILV--ENKMKIYGVEVEIIDINDNFPRFRDEELKVKVNEN 145
Query: 150 AAVGTRIPLDSAFDPDVGENSLHTYSLSANDFFNIEVRTRTDGAKYAELIVVRELDRELK 209
AA GTR+ L A D DVG NSL +Y LS+N F+++V + TDG KY EL++ + LDRE +
Sbjct: 146 AAAGTRLVLPFARDADVGVNSLRSYQLSSNLHFSLDVVSGTDGQKYPELVLEQPLDREKE 205
Query: 210 SSYELQLTASDMGVPQRSGSSILKISISDSNDNSPAFEQQSYIIQLLENSPVGTLLLDLN 269
+ ++L LTA D G P SG++ +++++ D+NDN+P F Y + + EN PVGT LL L
Sbjct: 206 TVHDLLLTALDGGDPVLSGTTHIRVTVLDANDNAPLFTPSEYSVSVPENIPVGTRLLMLT 265
Query: 270 ATDPDEGANGKIVYSFSSHVSPKIMETFKIDSERGHLTLFKQVDYEITKSYEIDVQAQDL 329
ATDPDEG NGK+ YSF + KI ETF++DS G ++ + +DYE ++ Y ++V AQD
Sbjct: 266 ATDPDEGINGKLTYSFRNE-EEKISETFQLDSNLGEISTLQSLDYEESRFYLMEVVAQDG 324
Query: 330 GPNSIPAHCKIIIKVVDVNDNKPEININLMSPGKEEISYIFEGDPIDTFVALVRVQDKDS 389
G ++ A K+++ V DVNDN PE+ + ++ S I E T +AL V D DS
Sbjct: 325 G--ALVASAKVVVTVQDVNDNAPEVILTSLT------SSISEDCLPGTVIALFSVHDGDS 376
Query: 390 GLNGEIVCKLHGHGHFKLQKTYENNYLILTNATLDREKRSEYSLTVIAEDRGTPSLSTVK 449
G NGEI C + + FKL+K+ +N Y +LT LDRE+ S+Y++T+ D GTP LST
Sbjct: 377 GENGEIACSIPRNLPFKLEKSVDNYYHLLTTRDLDREETSDYNITLTVMDHGTPPLSTES 436
Query: 450 HFTVQINDINDNPPHFQRSRYEFVISENNSPGAYITTVTATDPDLGENGQVTYTILESFI 509
H +++ D+NDNPP+F ++ Y ++ENN G I +VTA DPD G+N +VTY++ E
Sbjct: 437 HIPLKVADVNDNPPNFPQASYSTSVTENNPRGVSIFSVTAHDPDSGDNARVTYSLAEDTF 496
Query: 510 LGSSITTYVTIDPSNGAIYALRIFDHEEVSQITFVVEARDGGSPKQLVSNTTVVLTIIDE 569
G+ +++YV+I+ G +YALR FD+E++ + V A D G+P L SN ++ L ++D+
Sbjct: 497 QGAPLSSYVSINSDTGVLYALRSFDYEQLRDLQLWVTASDSGNP-PLSSNVSLSLFVLDQ 555
Query: 570 NDNVPVVIGPAL--RNNTAEITIPKGAESGFHVTRIRAIDRDSGVNAELSCAIVAGNEEN 627
NDN P ++ PAL +T P+ AE G+ VT++ A+D+DSG NA LS ++ +E
Sbjct: 556 NDNTPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDKDSGQNAWLSYRLLKASEPG 615
Query: 628 IFIIDPRSCDIHTNVSMDSVPYTEWELSVIIQDKGNPQLHTKVLLKCMIFEYAESVTS-- 685
+F + + ++ T ++ + L V ++D G P L + + + + +
Sbjct: 616 LFAVGLHTGEVRTARALLDRDALKQSLVVAVEDHGQPPLSATFTVTVAVADRIPDILADL 675
Query: 686 -TAMTSVSQASLDVSMIIIISLGAI-CAVLLVIMVLFATRCNREKK 729
+ T + LD+++ +++++ A+ C L ++VL R R K
Sbjct: 676 GSIKTPIDPEDLDLTLYLVVAVAAVSCVFLAFVIVLLVLRLRRWHK 721
>gi|11056024 protocadherin gamma subfamily A, 5 isoform 1 precursor
[Homo sapiens]
Length = 931
Score = 468 bits (1203), Expect = e-131
Identities = 257/706 (36%), Positives = 422/706 (59%), Gaps = 21/706 (2%)
Query: 30 LKYRIYEEQRVGSVIARLSEDVADVLLKLPNPSTVRFRAMQRGNSPLLVVNEDNGEISIG 89
++Y + EE GS + +++D+ L+ + R + RG + L +N +G +
Sbjct: 31 IRYSMPEELDKGSFVGNIAKDLG---LEPQELAERGVRIVSRGRTQLFALNPRSGSLVTA 87
Query: 90 ATIDREQLCQKNLNCSIEFDVITLPTEHLQLFHIEVEVLDINDNSPQFSRSLIPIEISES 149
IDRE+LC ++ C + F+++ ++++ +EVE++DINDN P+F + ++++E+
Sbjct: 88 GRIDREELCAQSPLCVVNFNILV--ENKMKIYGVEVEIIDINDNFPRFRDEELKVKVNEN 145
Query: 150 AAVGTRIPLDSAFDPDVGENSLHTYSLSANDFFNIEVRTRTDGAKYAELIVVRELDRELK 209
AA GTR+ L A D DVG NSL +Y LS+N F+++V + TDG KY EL++ + LDRE +
Sbjct: 146 AAAGTRLVLPFARDADVGVNSLRSYQLSSNLHFSLDVVSGTDGQKYPELVLEQPLDREKE 205
Query: 210 SSYELQLTASDMGVPQRSGSSILKISISDSNDNSPAFEQQSYIIQLLENSPVGTLLLDLN 269
+ ++L LTA D G P SG++ +++++ D+NDN+P F Y + + EN PVGT LL L
Sbjct: 206 TVHDLLLTALDGGDPVLSGTTHIRVTVLDANDNAPLFTPSEYSVSVPENIPVGTRLLMLT 265
Query: 270 ATDPDEGANGKIVYSFSSHVSPKIMETFKIDSERGHLTLFKQVDYEITKSYEIDVQAQDL 329
ATDPDEG NGK+ YSF + KI ETF++DS G ++ + +DYE ++ Y ++V AQD
Sbjct: 266 ATDPDEGINGKLTYSFRNE-EEKISETFQLDSNLGEISTLQSLDYEESRFYLMEVVAQDG 324
Query: 330 GPNSIPAHCKIIIKVVDVNDNKPEININLMSPGKEEISYIFEGDPIDTFVALVRVQDKDS 389
G ++ A K+++ V DVNDN PE+ + ++ S I E T +AL V D DS
Sbjct: 325 G--ALVASAKVVVTVQDVNDNAPEVILTSLT------SSISEDCLPGTVIALFSVHDGDS 376
Query: 390 GLNGEIVCKLHGHGHFKLQKTYENNYLILTNATLDREKRSEYSLTVIAEDRGTPSLSTVK 449
G NGEI C + + FKL+K+ +N Y +LT LDRE+ S+Y++T+ D GTP LST
Sbjct: 377 GENGEIACSIPRNLPFKLEKSVDNYYHLLTTRDLDREETSDYNITLTVMDHGTPPLSTES 436
Query: 450 HFTVQINDINDNPPHFQRSRYEFVISENNSPGAYITTVTATDPDLGENGQVTYTILESFI 509
H +++ D+NDNPP+F ++ Y ++ENN G I +VTA DPD G+N +VTY++ E
Sbjct: 437 HIPLKVADVNDNPPNFPQASYSTSVTENNPRGVSIFSVTAHDPDSGDNARVTYSLAEDTF 496
Query: 510 LGSSITTYVTIDPSNGAIYALRIFDHEEVSQITFVVEARDGGSPKQLVSNTTVVLTIIDE 569
G+ +++YV+I+ G +YALR FD+E++ + V A D G+P L SN ++ L ++D+
Sbjct: 497 QGAPLSSYVSINSDTGVLYALRSFDYEQLRDLQLWVTASDSGNP-PLSSNVSLSLFVLDQ 555
Query: 570 NDNVPVVIGPAL--RNNTAEITIPKGAESGFHVTRIRAIDRDSGVNAELSCAIVAGNEEN 627
NDN P ++ PAL +T P+ AE G+ VT++ A+D+DSG NA LS ++ +E
Sbjct: 556 NDNTPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDKDSGQNAWLSYRLLKASEPG 615
Query: 628 IFIIDPRSCDIHTNVSMDSVPYTEWELSVIIQDKGNPQLHTKVLLKCMIFEYAESVTS-- 685
+F + + ++ T ++ + L V ++D G P L + + + + +
Sbjct: 616 LFAVGLHTGEVRTARALLDRDALKQSLVVAVEDHGQPPLSATFTVTVAVADRIPDILADL 675
Query: 686 -TAMTSVSQASLDVSMIIIISLGAI-CAVLLVIMVLFATRCNREKK 729
+ T + LD+++ +++++ A+ C L ++VL R R K
Sbjct: 676 GSIKTPIDPEDLDLTLYLVVAVAAVSCVFLAFVIVLLVLRLRRWHK 721
>gi|11128043 protocadherin gamma subfamily A, 9 isoform 1 precursor
[Homo sapiens]
Length = 932
Score = 466 bits (1199), Expect = e-131
Identities = 266/720 (36%), Positives = 414/720 (57%), Gaps = 23/720 (3%)
Query: 11 RFVFALLIVSFNHDVLGKNLKYRIYEEQRVGSVIARLSEDVADVLLKLPNPSTVRFRAMQ 70
R V ++ + ++Y + EE G ++ +S+D+A L+ + R R +
Sbjct: 12 RLVLLCSLLGMLWEARASQIRYSVPEETEKGYIVGNISKDLA---LEPRELAERRVRIVS 68
Query: 71 RGNSPLLVVNEDNGEISIGATIDREQLCQKNLNCSIEFDVITLPTEHLQLFHIEVEVLDI 130
RG + L +N +G + IDRE+LC ++ C + F V+ + ++L+ IE+EV DI
Sbjct: 69 RGRTQLFSLNPRSGTLVTAGRIDREELCAQSPRCLVNFKVLV--EDRVKLYGIEIEVTDI 126
Query: 131 NDNSPQFSRSLIPIEISESAAVGTRIPLDSAFDPDVGENSLHTYSLSANDFFNIEVRTRT 190
ND++P+F + ++I+E A G R PL A DPDVG NSL +Y LS N F++ V+T
Sbjct: 127 NDSAPKFQAESLEVKINEIAVPGARYPLPEAIDPDVGVNSLQSYQLSPNHHFSLNVQTGD 186
Query: 191 DGAKYAELIVVRELDRELKSSYELQLTASDMGVPQRSGSSILKISISDSNDNSPAFEQQS 250
+GA EL++ R LDRE +++ L LTASD G P+RS + + +++ D+NDN+P F Q+
Sbjct: 187 NGAINPELVLERALDREEATAHHLVLTASDGGEPRRSSTVRIHVTVLDTNDNAPVFAQRI 246
Query: 251 YIIQLLENSPVGTLLLDLNATDPDEGANGKIVYSFSSHVSPKIMETFKIDSERGHLTLFK 310
Y +++LEN P GT LL A+D DEG NGK+ Y F ++ K F+++ G ++ K
Sbjct: 247 YRVKVLENVPPGTWLLTATASDLDEGINGKVAYKFWK-INEKQSLLFQLNENTGEISTAK 305
Query: 311 QVDYEITKSYEIDVQAQDLGPNSIPAHCKIIIKVVDVNDNKPEINI-NLMSPGKEEISYI 369
+DYE YE+++QA+D G + K++I V DVNDN+PE+ I +L SP +E+
Sbjct: 306 SLDYEECSFYEMEIQAEDGG--GLKGWTKVLISVEDVNDNRPEVTITSLFSPVREDA--- 360
Query: 370 FEGDPIDTFVALVRVQDKDSGLNGEIVCKLHGHGHFKLQKTYENNYLILTNATLDREKRS 429
P T + L D+DSG NG++VC + + F L+ + E+ Y +LT LDREK S
Sbjct: 361 ----PQGTVILLFNAHDRDSGKNGQVVCSIQENLSFTLENSEEDYYRLLTAQILDREKAS 416
Query: 430 EYSLTVIAEDRGTPSLSTVKHFTVQINDINDNPPHFQRSRYEFVISENNSPGAYITTVTA 489
EY++TV A DRGTP LST H T+Q+ DINDNPP F ++ Y + ENN+ G I +V A
Sbjct: 417 EYNITVTATDRGTPPLSTEIHITLQVTDINDNPPAFSQASYSVYLPENNARGTSIFSVIA 476
Query: 490 TDPDLGENGQVTYTILESFILGSSITTYVTIDPSNGAIYALRIFDHEEVSQITFVVEARD 549
DPD EN +V Y++ E I GS ++TYV+I+ G +YAL FD+E+ + V A D
Sbjct: 477 YDPDSNENSRVIYSLAEDTIQGSPLSTYVSINSDTGVLYALCSFDYEQFRDLQMQVTASD 536
Query: 550 GGSPKQLVSNTTVVLTIIDENDNVPVVIGPAL--RNNTAEITIPKGAESGFHVTRIRAID 607
GSP L SN ++ L ++D+NDN P ++ PAL +T P+ AE G+ VT++ A+D
Sbjct: 537 SGSP-PLSSNVSLRLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVD 595
Query: 608 RDSGVNAELSCAIVAGNEENIFIIDPRSCDIHTNVSMDSVPYTEWELSVIIQDKGNPQLH 667
RDSG NA LS + +E +F + + ++ T ++ + L V +QD G P L
Sbjct: 596 RDSGQNAWLSYRLFKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLS 655
Query: 668 TKVLLKCMIFEYAESVTSTAMTSVSQASL---DVSMIIIISLGAI-CAVLLVIMVLFATR 723
V L I + + + + A L D+++ +++++ + C L ++ L A R
Sbjct: 656 ATVTLTVAIADSIPDILADLGSLQIPADLEASDLTLYLVVAVAVVSCVFLTFVITLLALR 715
>gi|14270487 protocadherin gamma subfamily A, 9 isoform 2 precursor
[Homo sapiens]
Length = 828
Score = 466 bits (1199), Expect = e-131
Identities = 266/720 (36%), Positives = 414/720 (57%), Gaps = 23/720 (3%)
Query: 11 RFVFALLIVSFNHDVLGKNLKYRIYEEQRVGSVIARLSEDVADVLLKLPNPSTVRFRAMQ 70
R V ++ + ++Y + EE G ++ +S+D+A L+ + R R +
Sbjct: 12 RLVLLCSLLGMLWEARASQIRYSVPEETEKGYIVGNISKDLA---LEPRELAERRVRIVS 68
Query: 71 RGNSPLLVVNEDNGEISIGATIDREQLCQKNLNCSIEFDVITLPTEHLQLFHIEVEVLDI 130
RG + L +N +G + IDRE+LC ++ C + F V+ + ++L+ IE+EV DI
Sbjct: 69 RGRTQLFSLNPRSGTLVTAGRIDREELCAQSPRCLVNFKVLV--EDRVKLYGIEIEVTDI 126
Query: 131 NDNSPQFSRSLIPIEISESAAVGTRIPLDSAFDPDVGENSLHTYSLSANDFFNIEVRTRT 190
ND++P+F + ++I+E A G R PL A DPDVG NSL +Y LS N F++ V+T
Sbjct: 127 NDSAPKFQAESLEVKINEIAVPGARYPLPEAIDPDVGVNSLQSYQLSPNHHFSLNVQTGD 186
Query: 191 DGAKYAELIVVRELDRELKSSYELQLTASDMGVPQRSGSSILKISISDSNDNSPAFEQQS 250
+GA EL++ R LDRE +++ L LTASD G P+RS + + +++ D+NDN+P F Q+
Sbjct: 187 NGAINPELVLERALDREEATAHHLVLTASDGGEPRRSSTVRIHVTVLDTNDNAPVFAQRI 246
Query: 251 YIIQLLENSPVGTLLLDLNATDPDEGANGKIVYSFSSHVSPKIMETFKIDSERGHLTLFK 310
Y +++LEN P GT LL A+D DEG NGK+ Y F ++ K F+++ G ++ K
Sbjct: 247 YRVKVLENVPPGTWLLTATASDLDEGINGKVAYKFWK-INEKQSLLFQLNENTGEISTAK 305
Query: 311 QVDYEITKSYEIDVQAQDLGPNSIPAHCKIIIKVVDVNDNKPEINI-NLMSPGKEEISYI 369
+DYE YE+++QA+D G + K++I V DVNDN+PE+ I +L SP +E+
Sbjct: 306 SLDYEECSFYEMEIQAEDGG--GLKGWTKVLISVEDVNDNRPEVTITSLFSPVREDA--- 360
Query: 370 FEGDPIDTFVALVRVQDKDSGLNGEIVCKLHGHGHFKLQKTYENNYLILTNATLDREKRS 429
P T + L D+DSG NG++VC + + F L+ + E+ Y +LT LDREK S
Sbjct: 361 ----PQGTVILLFNAHDRDSGKNGQVVCSIQENLSFTLENSEEDYYRLLTAQILDREKAS 416
Query: 430 EYSLTVIAEDRGTPSLSTVKHFTVQINDINDNPPHFQRSRYEFVISENNSPGAYITTVTA 489
EY++TV A DRGTP LST H T+Q+ DINDNPP F ++ Y + ENN+ G I +V A
Sbjct: 417 EYNITVTATDRGTPPLSTEIHITLQVTDINDNPPAFSQASYSVYLPENNARGTSIFSVIA 476
Query: 490 TDPDLGENGQVTYTILESFILGSSITTYVTIDPSNGAIYALRIFDHEEVSQITFVVEARD 549
DPD EN +V Y++ E I GS ++TYV+I+ G +YAL FD+E+ + V A D
Sbjct: 477 YDPDSNENSRVIYSLAEDTIQGSPLSTYVSINSDTGVLYALCSFDYEQFRDLQMQVTASD 536
Query: 550 GGSPKQLVSNTTVVLTIIDENDNVPVVIGPAL--RNNTAEITIPKGAESGFHVTRIRAID 607
GSP L SN ++ L ++D+NDN P ++ PAL +T P+ AE G+ VT++ A+D
Sbjct: 537 SGSP-PLSSNVSLRLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVD 595
Query: 608 RDSGVNAELSCAIVAGNEENIFIIDPRSCDIHTNVSMDSVPYTEWELSVIIQDKGNPQLH 667
RDSG NA LS + +E +F + + ++ T ++ + L V +QD G P L
Sbjct: 596 RDSGQNAWLSYRLFKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLS 655
Query: 668 TKVLLKCMIFEYAESVTSTAMTSVSQASL---DVSMIIIISLGAI-CAVLLVIMVLFATR 723
V L I + + + + A L D+++ +++++ + C L ++ L A R
Sbjct: 656 ATVTLTVAIADSIPDILADLGSLQIPADLEASDLTLYLVVAVAVVSCVFLTFVITLLALR 715
>gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens]
Length = 936
Score = 465 bits (1196), Expect = e-130
Identities = 262/709 (36%), Positives = 412/709 (58%), Gaps = 24/709 (3%)
Query: 30 LKYRIYEEQRVGSVIARLSEDVADVLLKLPNPSTVRFRAMQRGNSPLLVVNEDNGEISIG 89
L Y I EE + G+ + R+++D+ L+L FR +G LL VN NG + +
Sbjct: 30 LHYSIPEEAKHGTFVGRIAQDLG---LELAELVPRLFRVASKGRGDLLEVNLQNGILFVN 86
Query: 90 ATIDREQLCQKNLNCSIEFDVITLPTEHLQLFHIEVEVLDINDNSPQFSRSLIPIEISES 149
+ IDRE+LC++ CSI +VI LQ+FH+EV V DINDN P+FSR + I ES
Sbjct: 87 SRIDREELCRRRAECSIHLEVIV--DRPLQVFHVEVAVKDINDNPPRFSRQEQRLFILES 144
Query: 150 AAVGTRIPLDSAFDPDVGENSLHTYSLSANDFFNIEVRTRTDGAKYAELIVVRELDRELK 209
+R PL+ A D D+G N+ Y L+ N++F+++V+T + + EL++ + LDRE
Sbjct: 145 RMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLDVKTNEEETNFLELVLRKSLDREET 204
Query: 210 SSYELQLTASDMGVPQRSGSSILKISISDSNDNSPAFEQQSYIIQLLENSPVGTLLLDLN 269
+ L + A+D G P+ +G+ L I++ D+NDN+P F++ Y ++LLEN+P GTL++ LN
Sbjct: 205 QEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPEFDKSIYNVRLLENAPSGTLVIKLN 264
Query: 270 ATDPDEGANGKIVYSFSSHVSPKIMETFKIDSERGHLTLFKQVDYEITKSYEIDVQAQDL 329
A+D DEG N +IVY FS+ V + F I+S G + + ++DYE SYEI++ A D
Sbjct: 265 ASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGEIKVNGELDYEDYNSYEINIDAMDK 324
Query: 330 GPNSIPAHCKIIIKVVDVNDNKPEINI-NLMSPGKEEISYIFEGDPIDTFVALVRVQDKD 388
+ HCK+++K++DVNDN PE+ I L P KE+ P+ T +AL+ V D+D
Sbjct: 325 STFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKEDA-------PLSTVIALISVSDRD 377
Query: 389 SGLNGEIVCKLHGHGHFKLQKTYENNYLILTNATLDREKRSEYSLTVIAEDRGTPSLSTV 448
SG NG++ C L H FKL T++N Y ++ ++ LDRE S Y L V A D G+PSL
Sbjct: 378 SGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVYELVVTARDGGSPSLWAT 437
Query: 449 KHFTVQINDINDNPPHFQRSRYEFVISENNSPGAYITTVTATDPDLGENGQVTYTILESF 508
+V++ D+NDN P F + +Y + ENN PG +I TV+A D D EN V+Y+++E
Sbjct: 438 ASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVERR 497
Query: 509 ILGSSITTYVTIDPSNGAIYALRIFDHEEVSQITFVVEARDGGSPKQLVSNTTVVLTIID 568
+ +++YV++ +G +YAL+ DHEEV + F V ARD G P L SN T+ + ++D
Sbjct: 498 VGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVP-PLGSNVTLQVFVLD 556
Query: 569 ENDNVPVVIGPALRNNTAEIT--IPKGAESGFHVTRIRAIDRDSGVNAELSCAI--VAGN 624
ENDN P ++ P + ++ +P+ +G V ++RA+D DSG NA LS + G+
Sbjct: 557 ENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDSGYNAWLSYELQPAPGS 616
Query: 625 EENIFIIDPRSCDIHTNVSMDSVPYTEWELSVIIQDKGNPQLHTKVLLKCMIFE-----Y 679
F + + +I T S+D L V+++D G P L + + E
Sbjct: 617 ARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTATATVLVSLVESGQAPK 676
Query: 680 AESVTSTAMTSVSQASLDVSMIIIISLGAICAVLLVIMVLF-ATRCNRE 727
A S S A +DV++ +II++ A+ ++L++ ++L+ A RC+ +
Sbjct: 677 ASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAQ 725
>gi|14165416 protocadherin alpha 5 isoform 2 precursor [Homo
sapiens]
Length = 816
Score = 465 bits (1196), Expect = e-130
Identities = 262/709 (36%), Positives = 412/709 (58%), Gaps = 24/709 (3%)
Query: 30 LKYRIYEEQRVGSVIARLSEDVADVLLKLPNPSTVRFRAMQRGNSPLLVVNEDNGEISIG 89
L Y I EE + G+ + R+++D+ L+L FR +G LL VN NG + +
Sbjct: 30 LHYSIPEEAKHGTFVGRIAQDLG---LELAELVPRLFRVASKGRGDLLEVNLQNGILFVN 86
Query: 90 ATIDREQLCQKNLNCSIEFDVITLPTEHLQLFHIEVEVLDINDNSPQFSRSLIPIEISES 149
+ IDRE+LC++ CSI +VI LQ+FH+EV V DINDN P+FSR + I ES
Sbjct: 87 SRIDREELCRRRAECSIHLEVIV--DRPLQVFHVEVAVKDINDNPPRFSRQEQRLFILES 144
Query: 150 AAVGTRIPLDSAFDPDVGENSLHTYSLSANDFFNIEVRTRTDGAKYAELIVVRELDRELK 209
+R PL+ A D D+G N+ Y L+ N++F+++V+T + + EL++ + LDRE
Sbjct: 145 RMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLDVKTNEEETNFLELVLRKSLDREET 204
Query: 210 SSYELQLTASDMGVPQRSGSSILKISISDSNDNSPAFEQQSYIIQLLENSPVGTLLLDLN 269
+ L + A+D G P+ +G+ L I++ D+NDN+P F++ Y ++LLEN+P GTL++ LN
Sbjct: 205 QEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPEFDKSIYNVRLLENAPSGTLVIKLN 264
Query: 270 ATDPDEGANGKIVYSFSSHVSPKIMETFKIDSERGHLTLFKQVDYEITKSYEIDVQAQDL 329
A+D DEG N +IVY FS+ V + F I+S G + + ++DYE SYEI++ A D
Sbjct: 265 ASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGEIKVNGELDYEDYNSYEINIDAMDK 324
Query: 330 GPNSIPAHCKIIIKVVDVNDNKPEINI-NLMSPGKEEISYIFEGDPIDTFVALVRVQDKD 388
+ HCK+++K++DVNDN PE+ I L P KE+ P+ T +AL+ V D+D
Sbjct: 325 STFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKEDA-------PLSTVIALISVSDRD 377
Query: 389 SGLNGEIVCKLHGHGHFKLQKTYENNYLILTNATLDREKRSEYSLTVIAEDRGTPSLSTV 448
SG NG++ C L H FKL T++N Y ++ ++ LDRE S Y L V A D G+PSL
Sbjct: 378 SGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVYELVVTARDGGSPSLWAT 437
Query: 449 KHFTVQINDINDNPPHFQRSRYEFVISENNSPGAYITTVTATDPDLGENGQVTYTILESF 508
+V++ D+NDN P F + +Y + ENN PG +I TV+A D D EN V+Y+++E
Sbjct: 438 ASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVERR 497
Query: 509 ILGSSITTYVTIDPSNGAIYALRIFDHEEVSQITFVVEARDGGSPKQLVSNTTVVLTIID 568
+ +++YV++ +G +YAL+ DHEEV + F V ARD G P L SN T+ + ++D
Sbjct: 498 VGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVP-PLGSNVTLQVFVLD 556
Query: 569 ENDNVPVVIGPALRNNTAEIT--IPKGAESGFHVTRIRAIDRDSGVNAELSCAI--VAGN 624
ENDN P ++ P + ++ +P+ +G V ++RA+D DSG NA LS + G+
Sbjct: 557 ENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDSGYNAWLSYELQPAPGS 616
Query: 625 EENIFIIDPRSCDIHTNVSMDSVPYTEWELSVIIQDKGNPQLHTKVLLKCMIFE-----Y 679
F + + +I T S+D L V+++D G P L + + E
Sbjct: 617 ARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTATATVLVSLVESGQAPK 676
Query: 680 AESVTSTAMTSVSQASLDVSMIIIISLGAICAVLLVIMVLF-ATRCNRE 727
A S S A +DV++ +II++ A+ ++L++ ++L+ A RC+ +
Sbjct: 677 ASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAQ 725
>gi|11056032 protocadherin gamma subfamily A, 1 isoform 1 precursor
[Homo sapiens]
Length = 931
Score = 464 bits (1195), Expect = e-130
Identities = 264/707 (37%), Positives = 414/707 (58%), Gaps = 21/707 (2%)
Query: 29 NLKYRIYEEQRVGSVIARLSEDVADVLLKLPNPSTVRFRAMQRGNSPLLVVNEDNGEISI 88
N+ Y + EE GS + +++D+ +L + R + RG PL +N +G +
Sbjct: 30 NIHYSVPEETDKGSFVGNIAKDLGLQPQELADGGV---RIVSRGRMPLFALNPRSGSLIT 86
Query: 89 GATIDREQLCQKNLNCSIEFDVITLPTEHLQLFHIEVEVLDINDNSPQFSRSLIPIEISE 148
IDRE+LC +++ C + F+++ + ++LF +EVE++DINDN+PQF + +++E
Sbjct: 87 ARRIDREELCAQSMPCLVSFNILV--EDKMKLFPVEVEIIDINDNTPQFQLEELEFKMNE 144
Query: 149 SAAVGTRIPLDSAFDPDVGENSLHTYSLSANDFFNIEVRTRTDGAKYAELIVVRELDREL 208
GTR+ L D DVG NSL +Y LS+N F+++V+ DG ++ E+++ LDRE
Sbjct: 145 ITTPGTRVSLPFGQDLDVGMNSLQSYQLSSNPHFSLDVQQGADGPQHPEMVLQSPLDREE 204
Query: 209 KSSYELQLTASDMGVPQRSGSSILKISISDSNDNSPAFEQQSYIIQLLENSPVGTLLLDL 268
++ + L LTASD G P RSG+ + I + D+NDN PAF Q Y I + EN P+GT LL +
Sbjct: 205 EAVHHLILTASDGGEPVRSGTLRIYIQVVDANDNPPAFTQAQYHINVPENVPLGTQLLMV 264
Query: 269 NATDPDEGANGKIVYSFSSHVSPKIMETFKIDSERGHLTLFKQVDYEITKSYEIDVQAQD 328
NATDPDEGANG++ YSF +V ++ + F++DS G ++ + +D+E K Y ++VQAQD
Sbjct: 265 NATDPDEGANGEVTYSF-HNVDHRVAQIFRLDSYTGEISNKEPLDFEEYKMYSMEVQAQD 323
Query: 329 LGPNSIPAHCKIIIKVVDVNDNKPEININLMSPGKEEISYIFEGDPIDTFVALVRVQDKD 388
+ A K++IKV+DVNDN PE+ I ++ + + E P T +AL+ V D+D
Sbjct: 324 --GAGLMAKVKVLIKVLDVNDNAPEVTITSVT------TAVPENFPPGTIIALISVHDQD 375
Query: 389 SGLNGEIVCKLHGHGHFKLQKTYENNYLILTNATLDREKRSEYSLTVIAEDRGTPSLSTV 448
SG NG C + G+ FKL+K +N Y ++T TLDRE S Y++T+ A D+GTP+LST
Sbjct: 376 SGDNGYTTCFIPGNLPFKLEKLVDNYYRLVTERTLDRELISGYNITITAIDQGTPALSTE 435
Query: 449 KHFTVQINDINDNPPHFQRSRYEFVISENNSPGAYITTVTATDPDLGENGQVTYTILESF 508
H ++ + DINDN P F + Y I ENN GA I +V A D D EN Q+TY+++E
Sbjct: 436 THISLLVTDINDNSPVFHQDSYSAYIPENNPRGASIFSVRAHDLDSNENAQITYSLIEDT 495
Query: 509 ILGSSITTYVTIDPSNGAIYALRIFDHEEVSQITFVVEARDGGSPKQLVSNTTVVLTIID 568
I G+ ++ Y++I+ G +YALR FD+E+ + V ARD G P L SN ++ L ++D
Sbjct: 496 IQGAPLSAYLSINSDTGVLYALRSFDYEQFRDMQLKVMARDSGDP-PLSSNVSLSLFLLD 554
Query: 569 ENDNVPVVIGPAL--RNNTAEITIPKGAESGFHVTRIRAIDRDSGVNAELSCAIVAGNEE 626
+NDN P ++ PAL +T P AE G+ VT++ A+DRDSG NA LS ++ +E
Sbjct: 555 QNDNAPEILYPALPTDGSTGVELAPLSAEPGYLVTKVVAVDRDSGQNAWLSYRLLKASEP 614
Query: 627 NIFIIDPRSCDIHTNVSMDSVPYTEWELSVIIQDKGNPQLHTKVLLKCMIFEYAESVTS- 685
+F + + ++ T ++ + L V +QD G P L V L + + + +
Sbjct: 615 GLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADRISDILAD 674
Query: 686 --TAMTSVSQASLDVSMIIIISLGAI-CAVLLVIMVLFATRCNREKK 729
+ S D+++ ++++ A+ C L ++VL A R R K
Sbjct: 675 LGSLEPSAKPNDSDLTLYLVVAAAAVSCVFLAFVIVLLAHRLRRWHK 721
>gi|14196459 protocadherin gamma subfamily A, 1 isoform 2 precursor
[Homo sapiens]
Length = 823
Score = 464 bits (1195), Expect = e-130
Identities = 264/707 (37%), Positives = 414/707 (58%), Gaps = 21/707 (2%)
Query: 29 NLKYRIYEEQRVGSVIARLSEDVADVLLKLPNPSTVRFRAMQRGNSPLLVVNEDNGEISI 88
N+ Y + EE GS + +++D+ +L + R + RG PL +N +G +
Sbjct: 30 NIHYSVPEETDKGSFVGNIAKDLGLQPQELADGGV---RIVSRGRMPLFALNPRSGSLIT 86
Query: 89 GATIDREQLCQKNLNCSIEFDVITLPTEHLQLFHIEVEVLDINDNSPQFSRSLIPIEISE 148
IDRE+LC +++ C + F+++ + ++LF +EVE++DINDN+PQF + +++E
Sbjct: 87 ARRIDREELCAQSMPCLVSFNILV--EDKMKLFPVEVEIIDINDNTPQFQLEELEFKMNE 144
Query: 149 SAAVGTRIPLDSAFDPDVGENSLHTYSLSANDFFNIEVRTRTDGAKYAELIVVRELDREL 208
GTR+ L D DVG NSL +Y LS+N F+++V+ DG ++ E+++ LDRE
Sbjct: 145 ITTPGTRVSLPFGQDLDVGMNSLQSYQLSSNPHFSLDVQQGADGPQHPEMVLQSPLDREE 204
Query: 209 KSSYELQLTASDMGVPQRSGSSILKISISDSNDNSPAFEQQSYIIQLLENSPVGTLLLDL 268
++ + L LTASD G P RSG+ + I + D+NDN PAF Q Y I + EN P+GT LL +
Sbjct: 205 EAVHHLILTASDGGEPVRSGTLRIYIQVVDANDNPPAFTQAQYHINVPENVPLGTQLLMV 264
Query: 269 NATDPDEGANGKIVYSFSSHVSPKIMETFKIDSERGHLTLFKQVDYEITKSYEIDVQAQD 328
NATDPDEGANG++ YSF +V ++ + F++DS G ++ + +D+E K Y ++VQAQD
Sbjct: 265 NATDPDEGANGEVTYSF-HNVDHRVAQIFRLDSYTGEISNKEPLDFEEYKMYSMEVQAQD 323
Query: 329 LGPNSIPAHCKIIIKVVDVNDNKPEININLMSPGKEEISYIFEGDPIDTFVALVRVQDKD 388
+ A K++IKV+DVNDN PE+ I ++ + + E P T +AL+ V D+D
Sbjct: 324 --GAGLMAKVKVLIKVLDVNDNAPEVTITSVT------TAVPENFPPGTIIALISVHDQD 375
Query: 389 SGLNGEIVCKLHGHGHFKLQKTYENNYLILTNATLDREKRSEYSLTVIAEDRGTPSLSTV 448
SG NG C + G+ FKL+K +N Y ++T TLDRE S Y++T+ A D+GTP+LST
Sbjct: 376 SGDNGYTTCFIPGNLPFKLEKLVDNYYRLVTERTLDRELISGYNITITAIDQGTPALSTE 435
Query: 449 KHFTVQINDINDNPPHFQRSRYEFVISENNSPGAYITTVTATDPDLGENGQVTYTILESF 508
H ++ + DINDN P F + Y I ENN GA I +V A D D EN Q+TY+++E
Sbjct: 436 THISLLVTDINDNSPVFHQDSYSAYIPENNPRGASIFSVRAHDLDSNENAQITYSLIEDT 495
Query: 509 ILGSSITTYVTIDPSNGAIYALRIFDHEEVSQITFVVEARDGGSPKQLVSNTTVVLTIID 568
I G+ ++ Y++I+ G +YALR FD+E+ + V ARD G P L SN ++ L ++D
Sbjct: 496 IQGAPLSAYLSINSDTGVLYALRSFDYEQFRDMQLKVMARDSGDP-PLSSNVSLSLFLLD 554
Query: 569 ENDNVPVVIGPAL--RNNTAEITIPKGAESGFHVTRIRAIDRDSGVNAELSCAIVAGNEE 626
+NDN P ++ PAL +T P AE G+ VT++ A+DRDSG NA LS ++ +E
Sbjct: 555 QNDNAPEILYPALPTDGSTGVELAPLSAEPGYLVTKVVAVDRDSGQNAWLSYRLLKASEP 614
Query: 627 NIFIIDPRSCDIHTNVSMDSVPYTEWELSVIIQDKGNPQLHTKVLLKCMIFEYAESVTS- 685
+F + + ++ T ++ + L V +QD G P L V L + + + +
Sbjct: 615 GLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADRISDILAD 674
Query: 686 --TAMTSVSQASLDVSMIIIISLGAI-CAVLLVIMVLFATRCNREKK 729
+ S D+++ ++++ A+ C L ++VL A R R K
Sbjct: 675 LGSLEPSAKPNDSDLTLYLVVAAAAVSCVFLAFVIVLLAHRLRRWHK 721
>gi|14270499 protocadherin gamma subfamily B, 4 isoform 2 precursor
[Homo sapiens]
Length = 803
Score = 464 bits (1193), Expect = e-130
Identities = 260/728 (35%), Positives = 414/728 (56%), Gaps = 23/728 (3%)
Query: 13 VFALLIVSFNHDVLGKNLKYRIYEEQRVGSVIARLSEDVADVLLKLPNPSTVRFRAMQRG 72
V L ++S L + ++YRI EE GSV+ L+ D+ + +LP T + R
Sbjct: 16 VLFLFLLSLFCPALCEQIRYRIPEEMPKGSVVGNLATDLGFSVQELP---TRKLRVSSE- 71
Query: 73 NSPLLVVNEDNGEISIGATIDREQLCQKNLNCSIEFDVITLPTEHLQLFHIEVEVLDIND 132
P V+ ++GE+ + + +DRE++C K C++EF+ + L +H+ VE+ DIND
Sbjct: 72 -KPYFTVSAESGELLVSSRLDREEICGKKPACALEFEAVA--ENPLNFYHVNVEIEDIND 128
Query: 133 NSPQFSRSLIPIEISESAAVGTRIPLDSAFDPDVGENSLHTYSLSANDFFNIEVRTRTDG 192
++P+F+++ ++ISESA GTR L SA D D+G N+L Y LS +D F++ + ++DG
Sbjct: 129 HTPKFTQNSFELQISESAQPGTRFILGSAHDADIGSNTLQNYQLSPSDHFSLINKEKSDG 188
Query: 193 AKYAELIVVRELDRELKSSYELQLTASDMGVPQRSGSSILKISISDSNDNSPAFEQQSYI 252
+KY E+++ LDRE + SY L LTA D G P S ++ + + ++D+NDN+P F Q Y
Sbjct: 189 SKYPEMVLKTPLDREKQKSYHLTLTALDFGAPPLSSTAQIHVLVTDANDNAPVFSQDVYR 248
Query: 253 IQLLENSPVGTLLLDLNATDPDEGANGKIVYSFSSHVSPKIMETFKIDSERGHLTLFKQV 312
+ L EN GT +L + ATD DEG N +I +SFS + F ++S G +T+ +
Sbjct: 249 VSLSENVYPGTTVLQVTATDQDEGVNAEITFSFSEASQ---ITQFDLNSNTGEITVLNTL 305
Query: 313 DYEITKSYEIDVQAQDLGPNSIPAHCKIIIKVVDVNDNKPEININLMSPGKEEISYIFEG 372
D+E K Y I ++A+D G + A C + ++V+D NDN PE+ + + I E
Sbjct: 306 DFEEVKEYSIVLEARDGG--GMIAQCTVEVEVIDENDNAPEVIFQSLP------NLIMED 357
Query: 373 DPIDTFVALVRVQDKDSGLNGEIVCKLHGHGHFKLQKTYENNYLILTNATLDREKRSEYS 432
+ T +AL++V+DKDS NGE+ CKL G FK+ + N Y ++T+A LDRE+ EY+
Sbjct: 358 AELGTHIALLKVRDKDSRHNGEVTCKLEGDVPFKILTSSRNTYKLVTDAVLDREQNPEYN 417
Query: 433 LTVIAEDRGTPSLSTVKHFTVQINDINDNPPHFQRSRYEFVISENNSPGAYITTVTATDP 492
+TV A DRG P LS+ T+ I D+NDN P F +S Y ++ENN PGA I+ V A+DP
Sbjct: 418 ITVTATDRGKPPLSSSSSITLHIGDVNDNAPVFSQSSYIVHVAENNPPGASISQVRASDP 477
Query: 493 DLGENGQVTYTILESFILGSSITTYVTIDPSNGAIYALRIFDHEEVSQITFVVEARDGGS 552
DLG NGQV+Y I+ S + +++YV+I +G ++A R FDHE++ ++ARD GS
Sbjct: 478 DLGPNGQVSYCIMASDLEQRELSSYVSISAESGVVFAQRAFDHEQLRAFELTLQARDQGS 537
Query: 553 PKQLVSNTTVVLTIIDENDNVPVVIGPALRNNTAEI--TIPKGAESGFHVTRIRAIDRDS 610
P L +N ++ + + D NDN P V+ PAL + + + +P AE G+ VT++ A+D DS
Sbjct: 538 P-ALSANVSLRVLVDDRNDNAPRVLYPALGPDGSALFDMVPHAAEPGYLVTKVVAVDADS 596
Query: 611 GVNAELSCAIVAGNEENIFIIDPRSCDIHTNVSMDSVPYTEWELSVIIQDKGNPQLHTKV 670
G NA LS ++ +E +F + R+ ++ T ++ L V ++D G P L
Sbjct: 597 GHNAWLSYHVLQASEPGLFSLGLRTGEVRTARALGDRDAVRQRLLVAVRDGGQPPLSATA 656
Query: 671 LLKCMIFEYAESVTS--TAMTSVSQASLDVSMIIIISLGAICAVLLVIMVLFATRCNREK 728
L + + + V T S ++ ++++L I + LV M+L R
Sbjct: 657 TLHLVFADSLQEVLPDITDRPDPSDLQAELQFYLVVALALISVLFLVAMILAIALRLRRS 716
Query: 729 KDTRSYNC 736
S++C
Sbjct: 717 SSPASWSC 724
>gi|13470082 protocadherin gamma subfamily B, 4 isoform 1 precursor
[Homo sapiens]
Length = 923
Score = 464 bits (1193), Expect = e-130
Identities = 260/728 (35%), Positives = 414/728 (56%), Gaps = 23/728 (3%)
Query: 13 VFALLIVSFNHDVLGKNLKYRIYEEQRVGSVIARLSEDVADVLLKLPNPSTVRFRAMQRG 72
V L ++S L + ++YRI EE GSV+ L+ D+ + +LP T + R
Sbjct: 16 VLFLFLLSLFCPALCEQIRYRIPEEMPKGSVVGNLATDLGFSVQELP---TRKLRVSSE- 71
Query: 73 NSPLLVVNEDNGEISIGATIDREQLCQKNLNCSIEFDVITLPTEHLQLFHIEVEVLDIND 132
P V+ ++GE+ + + +DRE++C K C++EF+ + L +H+ VE+ DIND
Sbjct: 72 -KPYFTVSAESGELLVSSRLDREEICGKKPACALEFEAVA--ENPLNFYHVNVEIEDIND 128
Query: 133 NSPQFSRSLIPIEISESAAVGTRIPLDSAFDPDVGENSLHTYSLSANDFFNIEVRTRTDG 192
++P+F+++ ++ISESA GTR L SA D D+G N+L Y LS +D F++ + ++DG
Sbjct: 129 HTPKFTQNSFELQISESAQPGTRFILGSAHDADIGSNTLQNYQLSPSDHFSLINKEKSDG 188
Query: 193 AKYAELIVVRELDRELKSSYELQLTASDMGVPQRSGSSILKISISDSNDNSPAFEQQSYI 252
+KY E+++ LDRE + SY L LTA D G P S ++ + + ++D+NDN+P F Q Y
Sbjct: 189 SKYPEMVLKTPLDREKQKSYHLTLTALDFGAPPLSSTAQIHVLVTDANDNAPVFSQDVYR 248
Query: 253 IQLLENSPVGTLLLDLNATDPDEGANGKIVYSFSSHVSPKIMETFKIDSERGHLTLFKQV 312
+ L EN GT +L + ATD DEG N +I +SFS + F ++S G +T+ +
Sbjct: 249 VSLSENVYPGTTVLQVTATDQDEGVNAEITFSFSEASQ---ITQFDLNSNTGEITVLNTL 305
Query: 313 DYEITKSYEIDVQAQDLGPNSIPAHCKIIIKVVDVNDNKPEININLMSPGKEEISYIFEG 372
D+E K Y I ++A+D G + A C + ++V+D NDN PE+ + + I E
Sbjct: 306 DFEEVKEYSIVLEARDGG--GMIAQCTVEVEVIDENDNAPEVIFQSLP------NLIMED 357
Query: 373 DPIDTFVALVRVQDKDSGLNGEIVCKLHGHGHFKLQKTYENNYLILTNATLDREKRSEYS 432
+ T +AL++V+DKDS NGE+ CKL G FK+ + N Y ++T+A LDRE+ EY+
Sbjct: 358 AELGTHIALLKVRDKDSRHNGEVTCKLEGDVPFKILTSSRNTYKLVTDAVLDREQNPEYN 417
Query: 433 LTVIAEDRGTPSLSTVKHFTVQINDINDNPPHFQRSRYEFVISENNSPGAYITTVTATDP 492
+TV A DRG P LS+ T+ I D+NDN P F +S Y ++ENN PGA I+ V A+DP
Sbjct: 418 ITVTATDRGKPPLSSSSSITLHIGDVNDNAPVFSQSSYIVHVAENNPPGASISQVRASDP 477
Query: 493 DLGENGQVTYTILESFILGSSITTYVTIDPSNGAIYALRIFDHEEVSQITFVVEARDGGS 552
DLG NGQV+Y I+ S + +++YV+I +G ++A R FDHE++ ++ARD GS
Sbjct: 478 DLGPNGQVSYCIMASDLEQRELSSYVSISAESGVVFAQRAFDHEQLRAFELTLQARDQGS 537
Query: 553 PKQLVSNTTVVLTIIDENDNVPVVIGPALRNNTAEI--TIPKGAESGFHVTRIRAIDRDS 610
P L +N ++ + + D NDN P V+ PAL + + + +P AE G+ VT++ A+D DS
Sbjct: 538 P-ALSANVSLRVLVDDRNDNAPRVLYPALGPDGSALFDMVPHAAEPGYLVTKVVAVDADS 596
Query: 611 GVNAELSCAIVAGNEENIFIIDPRSCDIHTNVSMDSVPYTEWELSVIIQDKGNPQLHTKV 670
G NA LS ++ +E +F + R+ ++ T ++ L V ++D G P L
Sbjct: 597 GHNAWLSYHVLQASEPGLFSLGLRTGEVRTARALGDRDAVRQRLLVAVRDGGQPPLSATA 656
Query: 671 LLKCMIFEYAESVTS--TAMTSVSQASLDVSMIIIISLGAICAVLLVIMVLFATRCNREK 728
L + + + V T S ++ ++++L I + LV M+L R
Sbjct: 657 TLHLVFADSLQEVLPDITDRPDPSDLQAELQFYLVVALALISVLFLVAMILAIALRLRRS 716
Query: 729 KDTRSYNC 736
S++C
Sbjct: 717 SSPASWSC 724
>gi|14196451 protocadherin gamma subfamily A, 11 isoform 2 precursor
[Homo sapiens]
Length = 837
Score = 462 bits (1190), Expect = e-130
Identities = 265/708 (37%), Positives = 414/708 (58%), Gaps = 21/708 (2%)
Query: 28 KNLKYRIYEEQRVGSVIARLSEDVADVLLKLPNPSTVRFRAMQRGNSPLLVVNEDNGEIS 87
+ ++Y + EE GS + +S+D+ +L R + RG + L VN +G +
Sbjct: 30 RQIRYSVPEETEKGSFVGNISKDLGLEPRELAKRGV---RIVSRGKTQLFAVNPRSGSLI 86
Query: 88 IGATIDREQLCQKNLNCSIEFDVITLPTEHLQLFHIEVEVLDINDNSPQFSRSLIPIEIS 147
IDRE+LC+ +C + +++ T L+++ +EVE++DINDN+P F + I++S
Sbjct: 87 TAGRIDREELCETVSSCFLNMELLVEDT--LKIYGVEVEIIDINDNAPSFQEDEVEIKVS 144
Query: 148 ESAAVGTRIPLDSAFDPDVGENSLHTYSLSANDFFNIEVRTRTDGAKYAELIVVRELDRE 207
E A G R L +A DPDVG NSL +Y LS N++F++++R RTDGAK EL++ LDRE
Sbjct: 145 EHAIPGARFALPNARDPDVGVNSLQSYQLSPNNYFSLQLRGRTDGAKNPELVLEGSLDRE 204
Query: 208 LKSSYELQLTASDMGVPQRSGSSILKISISDSNDNSPAFEQQSYIIQLLENSPVGTLLLD 267
++++ L LTA D G P R G+ +++ + D ND+ P F Q Y + + EN GT +L
Sbjct: 205 KEAAHLLLLTALDGGDPIRKGAVPIRVVVLDVNDHIPMFTQSVYRVSVPENISSGTRVLM 264
Query: 268 LNATDPDEGANGKIVYSFSSHVSPKIMETFKIDSERGHLTLFKQVDYEITKSYEIDVQAQ 327
+NATDPDEG NG+++YSF + S K E F++DS+ G + + +D+E + YE+++Q Q
Sbjct: 265 VNATDPDEGINGEVMYSFRNMES-KASEIFQLDSQTGEVQVRGSLDFEKYRFYEMEIQGQ 323
Query: 328 DLGPNSIPAHCKIIIKVVDVNDNKPEININLMSPGKEEISYIFEGDPIDTFVALVRVQDK 387
D G + ++I VVDVNDN PEI I I+ I E P T +AL+ VQD+
Sbjct: 324 DGG--GLFTTTTMLITVVDVNDNAPEITIT------SSINSILENSPPGTVIALLNVQDQ 375
Query: 388 DSGLNGEIVCKLHGHGHFKLQKTYENNYLILTNATLDREKRSEYSLTVIAEDRGTPSLST 447
DSG NG++ C + H FKL+KTY N Y ++T+ LDRE Y++T+ A D+G+P LS
Sbjct: 376 DSGENGQVSCFIPNHLPFKLEKTYGNYYKLITSRVLDRELVQSYNITLTATDQGSPPLSA 435
Query: 448 VKHFTVQINDINDNPPHFQRSRYEFVISENNSPGAYITTVTATDPDLGENGQVTYTILES 507
H + + D NDNPP F S Y I ENN GA I +VTA DPD +N VTY++ +
Sbjct: 436 ETHVWLNVADDNDNPPVFPHSSYSAYIPENNPRGASIFSVTALDPDSKQNALVTYSLTDD 495
Query: 508 FILGSSITTYVTIDPSNGAIYALRIFDHEEVSQITFVVEARDGGSPKQLVSNTTVVLTII 567
+ G +++YV+I+ + G +YAL+ FD+E+ + V ARD G P L SN ++ L ++
Sbjct: 496 TVQGVPLSSYVSINSNTGVLYALQSFDYEQFRDLELRVIARDSGDP-PLSSNVSLSLFVL 554
Query: 568 DENDNVPVVIGPAL--RNNTAEITIPKGAESGFHVTRIRAIDRDSGVNAELSCAIVAGNE 625
D+NDN P ++ PAL +T P+ AE G+ VT++ A+D+DSG NA LS ++ +E
Sbjct: 555 DQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDKDSGQNAWLSYRLLKASE 614
Query: 626 ENIFIIDPRSCDIHTNVSMDSVPYTEWELSVIIQDKGNPQLHTKVLLKCMIFEYAESVTS 685
+F + + ++ T ++ + L V +QD G P L V L + + V +
Sbjct: 615 PGLFAVGEHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSIPEVLA 674
Query: 686 TAMTSVSQA---SLDVSMIIIISLGAI-CAVLLVIMVLFATRCNREKK 729
+ S A + D+S+ +++++ A+ C L+ ++VL A R R K
Sbjct: 675 DLGSLESLANSETSDLSLYLVVAVAAVSCIFLVFVIVLLALRLWRWHK 722
>gi|11128039 protocadherin gamma subfamily A, 11 isoform 1 precursor
[Homo sapiens]
Length = 935
Score = 462 bits (1190), Expect = e-130
Identities = 265/708 (37%), Positives = 414/708 (58%), Gaps = 21/708 (2%)
Query: 28 KNLKYRIYEEQRVGSVIARLSEDVADVLLKLPNPSTVRFRAMQRGNSPLLVVNEDNGEIS 87
+ ++Y + EE GS + +S+D+ +L R + RG + L VN +G +
Sbjct: 30 RQIRYSVPEETEKGSFVGNISKDLGLEPRELAKRGV---RIVSRGKTQLFAVNPRSGSLI 86
Query: 88 IGATIDREQLCQKNLNCSIEFDVITLPTEHLQLFHIEVEVLDINDNSPQFSRSLIPIEIS 147
IDRE+LC+ +C + +++ T L+++ +EVE++DINDN+P F + I++S
Sbjct: 87 TAGRIDREELCETVSSCFLNMELLVEDT--LKIYGVEVEIIDINDNAPSFQEDEVEIKVS 144
Query: 148 ESAAVGTRIPLDSAFDPDVGENSLHTYSLSANDFFNIEVRTRTDGAKYAELIVVRELDRE 207
E A G R L +A DPDVG NSL +Y LS N++F++++R RTDGAK EL++ LDRE
Sbjct: 145 EHAIPGARFALPNARDPDVGVNSLQSYQLSPNNYFSLQLRGRTDGAKNPELVLEGSLDRE 204
Query: 208 LKSSYELQLTASDMGVPQRSGSSILKISISDSNDNSPAFEQQSYIIQLLENSPVGTLLLD 267
++++ L LTA D G P R G+ +++ + D ND+ P F Q Y + + EN GT +L
Sbjct: 205 KEAAHLLLLTALDGGDPIRKGAVPIRVVVLDVNDHIPMFTQSVYRVSVPENISSGTRVLM 264
Query: 268 LNATDPDEGANGKIVYSFSSHVSPKIMETFKIDSERGHLTLFKQVDYEITKSYEIDVQAQ 327
+NATDPDEG NG+++YSF + S K E F++DS+ G + + +D+E + YE+++Q Q
Sbjct: 265 VNATDPDEGINGEVMYSFRNMES-KASEIFQLDSQTGEVQVRGSLDFEKYRFYEMEIQGQ 323
Query: 328 DLGPNSIPAHCKIIIKVVDVNDNKPEININLMSPGKEEISYIFEGDPIDTFVALVRVQDK 387
D G + ++I VVDVNDN PEI I I+ I E P T +AL+ VQD+
Sbjct: 324 DGG--GLFTTTTMLITVVDVNDNAPEITIT------SSINSILENSPPGTVIALLNVQDQ 375
Query: 388 DSGLNGEIVCKLHGHGHFKLQKTYENNYLILTNATLDREKRSEYSLTVIAEDRGTPSLST 447
DSG NG++ C + H FKL+KTY N Y ++T+ LDRE Y++T+ A D+G+P LS
Sbjct: 376 DSGENGQVSCFIPNHLPFKLEKTYGNYYKLITSRVLDRELVQSYNITLTATDQGSPPLSA 435
Query: 448 VKHFTVQINDINDNPPHFQRSRYEFVISENNSPGAYITTVTATDPDLGENGQVTYTILES 507
H + + D NDNPP F S Y I ENN GA I +VTA DPD +N VTY++ +
Sbjct: 436 ETHVWLNVADDNDNPPVFPHSSYSAYIPENNPRGASIFSVTALDPDSKQNALVTYSLTDD 495
Query: 508 FILGSSITTYVTIDPSNGAIYALRIFDHEEVSQITFVVEARDGGSPKQLVSNTTVVLTII 567
+ G +++YV+I+ + G +YAL+ FD+E+ + V ARD G P L SN ++ L ++
Sbjct: 496 TVQGVPLSSYVSINSNTGVLYALQSFDYEQFRDLELRVIARDSGDP-PLSSNVSLSLFVL 554
Query: 568 DENDNVPVVIGPAL--RNNTAEITIPKGAESGFHVTRIRAIDRDSGVNAELSCAIVAGNE 625
D+NDN P ++ PAL +T P+ AE G+ VT++ A+D+DSG NA LS ++ +E
Sbjct: 555 DQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDKDSGQNAWLSYRLLKASE 614
Query: 626 ENIFIIDPRSCDIHTNVSMDSVPYTEWELSVIIQDKGNPQLHTKVLLKCMIFEYAESVTS 685
+F + + ++ T ++ + L V +QD G P L V L + + V +
Sbjct: 615 PGLFAVGEHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSIPEVLA 674
Query: 686 TAMTSVSQA---SLDVSMIIIISLGAI-CAVLLVIMVLFATRCNREKK 729
+ S A + D+S+ +++++ A+ C L+ ++VL A R R K
Sbjct: 675 DLGSLESLANSETSDLSLYLVVAVAAVSCIFLVFVIVLLALRLWRWHK 722
>gi|14589880 protocadherin gamma subfamily A, 3 isoform 1 precursor
[Homo sapiens]
Length = 932
Score = 462 bits (1189), Expect = e-130
Identities = 260/706 (36%), Positives = 411/706 (58%), Gaps = 21/706 (2%)
Query: 30 LKYRIYEEQRVGSVIARLSEDVADVLLKLPNPSTVRFRAMQRGNSPLLVVNEDNGEISIG 89
++Y + EE GS + ++ D+ +L R + RG + L +N +G +
Sbjct: 31 IRYSVSEELDKGSFVGNIANDLGLEPRELAERGV---RIVSRGRTQLFSLNPQSGSLVTA 87
Query: 90 ATIDREQLCQKNLNCSIEFDVITLPTEHLQLFHIEVEVLDINDNSPQFSRSLIPIEISES 149
IDRE+LC + C ++ +++ + L++F +E+E+ DINDN+P F + I+I E
Sbjct: 88 ERIDREELCAQIPLCLVKINILV--EDKLKIFEVEIEIKDINDNAPNFPTEELEIKIGEL 145
Query: 150 AAVGTRIPLDSAFDPDVGENSLHTYSLSANDFFNIEVRTRTDGAKYAELIVVRELDRELK 209
GTR P+ +AFDPDVG NSL Y LS ND+F++ V + ++GAKY EL++ R LDRE K
Sbjct: 146 TVPGTRFPIKTAFDPDVGINSLQNYKLSPNDYFSLAVNSVSEGAKYPELVLERALDREKK 205
Query: 210 SSYELQLTASDMGVPQRSGSSILKISISDSNDNSPAFEQQSYIIQLLENSPVGTLLLDLN 269
++L L ASD G P SG+ +++ + D+NDN P F Q Y + + EN PVGT LL +N
Sbjct: 206 EIHQLVLVASDGGDPVHSGNLHIQVIVLDANDNPPMFTQPEYRVSVWENVPVGTRLLTVN 265
Query: 270 ATDPDEGANGKIVYSFSSHVSPKIMETFKIDSERGHLTLFKQVDYEITKSYEIDVQAQDL 329
ATDPDEG N ++ Y + KI E F ++S G +++ K +DYE YEI ++AQD
Sbjct: 266 ATDPDEGFNAQVSYILDK-MPGKIAEIFHLNSVSGEVSILKSLDYEDAMFYEIKIEAQD- 323
Query: 330 GPNSIPAHCKIIIKVVDVNDNKPEININLMSPGKEEISYIFEGDPIDTFVALVRVQDKDS 389
GP + + KI++ V+DVNDN PEI I ++ S + E + +AL+ V D+DS
Sbjct: 324 GPGLL-SRAKILVTVLDVNDNAPEITITSLT------SSVPEEGTVGREIALIDVHDRDS 376
Query: 390 GLNGEIVCKLHGHGHFKLQKTYENNYLILTNATLDREKRSEYSLTVIAEDRGTPSLSTVK 449
G NG++ + G+ FKL+K+ + Y ++T +LDRE+ SEY++++ A D G+P LST
Sbjct: 377 GQNGQVEVFVLGNLPFKLEKSIDQYYRLVTATSLDREQISEYNISLRASDGGSPPLSTET 436
Query: 450 HFTVQINDINDNPPHFQRSRYEFVISENNSPGAYITTVTATDPDLGENGQVTYTILESFI 509
H T+ + DINDNPP F Y I ENN GA I +VTA DPD N ++TY + E +
Sbjct: 437 HITLHVIDINDNPPTFPHLSYSAYIPENNPRGASIFSVTAQDPDSNNNARITYALTEDTL 496
Query: 510 LGSSITTYVTIDPSNGAIYALRIFDHEEVSQITFVVEARDGGSPKQLVSNTTVVLTIIDE 569
G+ ++++V+I+ + G +YALR FD+E+ + +V A D G+P L SN ++ L ++D+
Sbjct: 497 QGAPLSSFVSINSNTGVLYALRSFDYEQFRDLKLLVTASDSGNP-PLSSNVSLNLFVLDQ 555
Query: 570 NDNVPVVIGPAL--RNNTAEITIPKGAESGFHVTRIRAIDRDSGVNAELSCAIVAGNEEN 627
NDN P ++ PAL +T P+ AE G+ VT++ A+DRDSG NA LS ++ +E
Sbjct: 556 NDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLLKASEPG 615
Query: 628 IFIIDPRSCDIHTNVSMDSVPYTEWELSVIIQDKGNPQLHTKVLLKCMIFEYAESVTS-- 685
+F + + ++ T ++ + L V +QD G P L V L + + + +
Sbjct: 616 LFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADRIPDILADL 675
Query: 686 -TAMTSVSQASLDVSMIIIISLGAI-CAVLLVIMVLFATRCNREKK 729
+ S D+++ +++++ A+ C L ++VL A R R K
Sbjct: 676 GSLEPSAKPNDSDLTLYLVVAVAAVSCVFLAFVIVLLALRLRRWHK 721
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.132 0.378
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 44,648,915
Number of Sequences: 37866
Number of extensions: 2173494
Number of successful extensions: 11445
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 184
Number of HSP's successfully gapped in prelim test: 40
Number of HSP's that attempted gapping in prelim test: 4670
Number of HSP's gapped (non-prelim): 784
length of query: 1135
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1022
effective length of database: 13,968,660
effective search space: 14275970520
effective search space used: 14275970520
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.