BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|145309317 tetratricopeptide repeat domain 30A [Homo sapiens] (665 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|145309317 tetratricopeptide repeat domain 30A [Homo sapiens] 1339 0.0 gi|125988411 tetratricopeptide repeat domain 30B [Homo sapiens] 1278 0.0 gi|225735593 RNA polymerase II associated protein 3 isoform 2 [H... 43 0.001 gi|225735591 RNA polymerase II associated protein 3 isoform 1 [H... 43 0.001 gi|225735595 RNA polymerase II associated protein 3 isoform 3 [H... 39 0.015 gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizi... 38 0.026 gi|194306559 kinesin light chain 1 isoform 3 [Homo sapiens] 37 0.059 gi|110735431 kinesin light chain 1 isoform 2 [Homo sapiens] 37 0.059 gi|33620730 kinesin light chain 1 isoform 1 [Homo sapiens] 37 0.059 gi|194353959 phosphoinositide-3-kinase, class 2 gamma polypeptid... 33 0.85 gi|21361356 translocase of outer mitochondrial membrane 34 [Homo... 33 0.85 gi|115430237 spectrin, beta, non-erythrocytic 4 isoform sigma1 [... 33 0.85 gi|91825557 kinesin light chain 3 [Homo sapiens] 33 1.1 gi|4557291 autoimmune regulator isoform 1 [Homo sapiens] 32 1.4 gi|157502177 tetratricopeptide repeat domain 21A isoform 2 [Homo... 32 2.5 gi|31377634 guanylate binding protein 4 [Homo sapiens] 31 3.2 gi|157502179 tetratricopeptide repeat domain 21A isoform 1 [Homo... 31 3.2 gi|21450645 tetratricopeptide repeat domain 16 [Homo sapiens] 31 3.2 gi|56119110 family with sequence similarity 13, member A1 isofor... 31 4.2 gi|62865869 family with sequence similarity 13, member A1 isofor... 31 4.2 gi|22749211 transmembrane and tetratricopeptide repeat containin... 31 4.2 gi|41871960 kinesin-like 8 isoform b [Homo sapiens] 31 4.2 gi|41871955 kinesin-like 8 isoform a [Homo sapiens] 31 4.2 gi|41871946 kinesin-like 8 isoform a [Homo sapiens] 31 4.2 gi|25952122 Bardet-Biedl syndrome 4 [Homo sapiens] 30 5.5 gi|4557495 cleavage stimulation factor subunit 3 isoform 1 [Homo... 30 5.5 gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens] 30 7.2 gi|24415404 MDN1, midasin homolog [Homo sapiens] 30 7.2 gi|148806872 lupus brain antigen 1 [Homo sapiens] 30 7.2 gi|37622896 LON peptidase N-terminal domain and ring finger 3 is... 30 7.2 >gi|145309317 tetratricopeptide repeat domain 30A [Homo sapiens] Length = 665 Score = 1339 bits (3466), Expect = 0.0 Identities = 665/665 (100%), Positives = 665/665 (100%) Query: 1 MAGLSGAQIPDGEFTALVYRLIRDARYAEAVQLLGRELQRSPRSRAGLSLLGYCYYRLQE 60 MAGLSGAQIPDGEFTALVYRLIRDARYAEAVQLLGRELQRSPRSRAGLSLLGYCYYRLQE Sbjct: 1 MAGLSGAQIPDGEFTALVYRLIRDARYAEAVQLLGRELQRSPRSRAGLSLLGYCYYRLQE 60 Query: 61 FALAAECYEQLGQLHPELEQYRLYQAQALYKACLYPEATRVAFLLLDNPAYHSRVLRLQA 120 FALAAECYEQLGQLHPELEQYRLYQAQALYKACLYPEATRVAFLLLDNPAYHSRVLRLQA Sbjct: 61 FALAAECYEQLGQLHPELEQYRLYQAQALYKACLYPEATRVAFLLLDNPAYHSRVLRLQA 120 Query: 121 AIKYSEGDLPGSRSLVEQLLSGEGGEESGGDNETDGQVNLGCLLYKEGQYEAACSKFSAT 180 AIKYSEGDLPGSRSLVEQLLSGEGGEESGGDNETDGQVNLGCLLYKEGQYEAACSKFSAT Sbjct: 121 AIKYSEGDLPGSRSLVEQLLSGEGGEESGGDNETDGQVNLGCLLYKEGQYEAACSKFSAT 180 Query: 181 LQASGYQPDLSYNLALAYYSSRQYASALKHIAEIIERGIRQHPELGVGMTTEGFDVRSVG 240 LQASGYQPDLSYNLALAYYSSRQYASALKHIAEIIERGIRQHPELGVGMTTEGFDVRSVG Sbjct: 181 LQASGYQPDLSYNLALAYYSSRQYASALKHIAEIIERGIRQHPELGVGMTTEGFDVRSVG 240 Query: 241 NTLVLHQTALVEAFNLKAAIEYQLRNYEVAQETLTDMPPRAEEELDPVTLHNQALMNMDA 300 NTLVLHQTALVEAFNLKAAIEYQLRNYEVAQETLTDMPPRAEEELDPVTLHNQALMNMDA Sbjct: 241 NTLVLHQTALVEAFNLKAAIEYQLRNYEVAQETLTDMPPRAEEELDPVTLHNQALMNMDA 300 Query: 301 RPTEGFEKLQFLLQQNPFPPETFGNLLLLYCKYEYFDLAADVLAENAHLTYKFLTPYLYD 360 RPTEGFEKLQFLLQQNPFPPETFGNLLLLYCKYEYFDLAADVLAENAHLTYKFLTPYLYD Sbjct: 301 RPTEGFEKLQFLLQQNPFPPETFGNLLLLYCKYEYFDLAADVLAENAHLTYKFLTPYLYD 360 Query: 361 FLDALITCQTAPEEAFIKLDGLAGMLTEQLRRLTKQVQEARHNRDDEAIKKAVNEYDETM 420 FLDALITCQTAPEEAFIKLDGLAGMLTEQLRRLTKQVQEARHNRDDEAIKKAVNEYDETM Sbjct: 361 FLDALITCQTAPEEAFIKLDGLAGMLTEQLRRLTKQVQEARHNRDDEAIKKAVNEYDETM 420 Query: 421 EKYIPVLMAQAKIYWNLENYPMVEKVFRKSVEFCNDHDVWKLNVAHVLFMQENKYKEAIG 480 EKYIPVLMAQAKIYWNLENYPMVEKVFRKSVEFCNDHDVWKLNVAHVLFMQENKYKEAIG Sbjct: 421 EKYIPVLMAQAKIYWNLENYPMVEKVFRKSVEFCNDHDVWKLNVAHVLFMQENKYKEAIG 480 Query: 481 FYEPIVKKHYDNILNVSAIVLANLCVSYIMTSQNEEAEELMRKIEKEEEQLSYDDPNRKM 540 FYEPIVKKHYDNILNVSAIVLANLCVSYIMTSQNEEAEELMRKIEKEEEQLSYDDPNRKM Sbjct: 481 FYEPIVKKHYDNILNVSAIVLANLCVSYIMTSQNEEAEELMRKIEKEEEQLSYDDPNRKM 540 Query: 541 YHLCIVNLVIGTLYCAKGNYEFGISRVIKSLEPYNKKLGTDTWYYAKRCFLSLLENMSKH 600 YHLCIVNLVIGTLYCAKGNYEFGISRVIKSLEPYNKKLGTDTWYYAKRCFLSLLENMSKH Sbjct: 541 YHLCIVNLVIGTLYCAKGNYEFGISRVIKSLEPYNKKLGTDTWYYAKRCFLSLLENMSKH 600 Query: 601 MIVIHDSVIQECVQFLGHCELYGTNIPAVIEQPLEEERMHVGKNTVTDESRQLKALIYEI 660 MIVIHDSVIQECVQFLGHCELYGTNIPAVIEQPLEEERMHVGKNTVTDESRQLKALIYEI Sbjct: 601 MIVIHDSVIQECVQFLGHCELYGTNIPAVIEQPLEEERMHVGKNTVTDESRQLKALIYEI 660 Query: 661 IGWNK 665 IGWNK Sbjct: 661 IGWNK 665 >gi|125988411 tetratricopeptide repeat domain 30B [Homo sapiens] Length = 665 Score = 1278 bits (3306), Expect = 0.0 Identities = 634/664 (95%), Positives = 647/664 (97%) Query: 1 MAGLSGAQIPDGEFTALVYRLIRDARYAEAVQLLGRELQRSPRSRAGLSLLGYCYYRLQE 60 MAGLSGAQIPDGEFTA+VYRLIR+ARYAEAVQLLG ELQRSPRSRAGLSLLGYCYYRLQE Sbjct: 1 MAGLSGAQIPDGEFTAVVYRLIRNARYAEAVQLLGGELQRSPRSRAGLSLLGYCYYRLQE 60 Query: 61 FALAAECYEQLGQLHPELEQYRLYQAQALYKACLYPEATRVAFLLLDNPAYHSRVLRLQA 120 FALAAECYEQLGQLHPELEQYRLYQAQALYKACLY EATRVAFLLLDNPAYHSRVLRLQA Sbjct: 61 FALAAECYEQLGQLHPELEQYRLYQAQALYKACLYAEATRVAFLLLDNPAYHSRVLRLQA 120 Query: 121 AIKYSEGDLPGSRSLVEQLLSGEGGEESGGDNETDGQVNLGCLLYKEGQYEAACSKFSAT 180 AIKYSEGDLPGSRSLVEQL S EGGEESGG+NETDGQ+NLGCLLYKEGQYEAACSKF A Sbjct: 121 AIKYSEGDLPGSRSLVEQLPSREGGEESGGENETDGQINLGCLLYKEGQYEAACSKFFAA 180 Query: 181 LQASGYQPDLSYNLALAYYSSRQYASALKHIAEIIERGIRQHPELGVGMTTEGFDVRSVG 240 LQASGYQPDLSYNLALAYYSSRQYASALKHIAEIIERGIRQHPELGVGMTTEG DVRSVG Sbjct: 181 LQASGYQPDLSYNLALAYYSSRQYASALKHIAEIIERGIRQHPELGVGMTTEGIDVRSVG 240 Query: 241 NTLVLHQTALVEAFNLKAAIEYQLRNYEVAQETLTDMPPRAEEELDPVTLHNQALMNMDA 300 NTLVLHQTALVEAFNLKAAIEYQLRNYE AQE LTDMPPRAEEELDPVTLHNQALMNMDA Sbjct: 241 NTLVLHQTALVEAFNLKAAIEYQLRNYEAAQEALTDMPPRAEEELDPVTLHNQALMNMDA 300 Query: 301 RPTEGFEKLQFLLQQNPFPPETFGNLLLLYCKYEYFDLAADVLAENAHLTYKFLTPYLYD 360 RPTEGFEKLQFLLQQNPFPPETFGNLLLLYCKYEYFDLAADVLAENAHL YKFLTPYLYD Sbjct: 301 RPTEGFEKLQFLLQQNPFPPETFGNLLLLYCKYEYFDLAADVLAENAHLIYKFLTPYLYD 360 Query: 361 FLDALITCQTAPEEAFIKLDGLAGMLTEQLRRLTKQVQEARHNRDDEAIKKAVNEYDETM 420 FLDA+ITCQTAPEEAFIKLDGLAGMLTE LR+LT QVQEARHNRDDEAIKKAVNEYDETM Sbjct: 361 FLDAVITCQTAPEEAFIKLDGLAGMLTEVLRKLTIQVQEARHNRDDEAIKKAVNEYDETM 420 Query: 421 EKYIPVLMAQAKIYWNLENYPMVEKVFRKSVEFCNDHDVWKLNVAHVLFMQENKYKEAIG 480 EKYIPVLMAQAKIYWNLENYPMVEK+FRKSVEFCNDHDVWKLNVAHVLFMQENKYKEAIG Sbjct: 421 EKYIPVLMAQAKIYWNLENYPMVEKIFRKSVEFCNDHDVWKLNVAHVLFMQENKYKEAIG 480 Query: 481 FYEPIVKKHYDNILNVSAIVLANLCVSYIMTSQNEEAEELMRKIEKEEEQLSYDDPNRKM 540 FYEPIVKKHYDNILNVSAIVLANLCVSYIMTSQNEEAEELMRKIEKEEEQLSYDDP++KM Sbjct: 481 FYEPIVKKHYDNILNVSAIVLANLCVSYIMTSQNEEAEELMRKIEKEEEQLSYDDPDKKM 540 Query: 541 YHLCIVNLVIGTLYCAKGNYEFGISRVIKSLEPYNKKLGTDTWYYAKRCFLSLLENMSKH 600 YHLCIVNLVIGTLYCAKGNY+FGISRVIKSLEPYNKKLGTDTWYYAKRCFLSLLENMSKH Sbjct: 541 YHLCIVNLVIGTLYCAKGNYDFGISRVIKSLEPYNKKLGTDTWYYAKRCFLSLLENMSKH 600 Query: 601 MIVIHDSVIQECVQFLGHCELYGTNIPAVIEQPLEEERMHVGKNTVTDESRQLKALIYEI 660 I++ DSVIQECVQFL HCEL+G NIPAVIEQPLEEERMHVGKNTVT ESRQLKALIYEI Sbjct: 601 TIMLRDSVIQECVQFLEHCELHGRNIPAVIEQPLEEERMHVGKNTVTYESRQLKALIYEI 660 Query: 661 IGWN 664 IGWN Sbjct: 661 IGWN 664 >gi|225735593 RNA polymerase II associated protein 3 isoform 2 [Homo sapiens] Length = 631 Score = 42.7 bits (99), Expect = 0.001 Identities = 43/202 (21%), Positives = 80/202 (39%), Gaps = 6/202 (2%) Query: 20 RLIRDARYAEAVQLLGRELQRSPRSRAGLSLLGYCYYRLQEFALAAECYEQLGQLHPELE 79 + + +Y EA+ + + P + + Y+RL++FA+A L+ Sbjct: 142 KYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYT 201 Query: 80 QYRLYQAQALYKACLYPEAT----RVAFLLLDNPAYHSRVLRLQAAIKYSEGDLPGSRSL 135 + + A + EA RV L +N + + ++ A+ E P + Sbjct: 202 KAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKISQALASKENSYPKEADI 261 Query: 136 VEQLLSGEGGEESGGDNETDG--QVNLGCLLYKEGQYEAACSKFSATLQASGYQPDLSYN 193 V + GE + N+ + + G +KEG+YE A ++ + A G L N Sbjct: 262 VIKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPAN 321 Query: 194 LALAYYSSRQYASALKHIAEII 215 A+AY ++Y A K + I Sbjct: 322 RAMAYLKIQKYEEAEKDCTQAI 343 >gi|225735591 RNA polymerase II associated protein 3 isoform 1 [Homo sapiens] Length = 665 Score = 42.7 bits (99), Expect = 0.001 Identities = 43/202 (21%), Positives = 80/202 (39%), Gaps = 6/202 (2%) Query: 20 RLIRDARYAEAVQLLGRELQRSPRSRAGLSLLGYCYYRLQEFALAAECYEQLGQLHPELE 79 + + +Y EA+ + + P + + Y+RL++FA+A L+ Sbjct: 142 KYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYT 201 Query: 80 QYRLYQAQALYKACLYPEAT----RVAFLLLDNPAYHSRVLRLQAAIKYSEGDLPGSRSL 135 + + A + EA RV L +N + + ++ A+ E P + Sbjct: 202 KAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKISQALASKENSYPKEADI 261 Query: 136 VEQLLSGEGGEESGGDNETDG--QVNLGCLLYKEGQYEAACSKFSATLQASGYQPDLSYN 193 V + GE + N+ + + G +KEG+YE A ++ + A G L N Sbjct: 262 VIKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPAN 321 Query: 194 LALAYYSSRQYASALKHIAEII 215 A+AY ++Y A K + I Sbjct: 322 RAMAYLKIQKYEEAEKDCTQAI 343 >gi|225735595 RNA polymerase II associated protein 3 isoform 3 [Homo sapiens] Length = 506 Score = 38.9 bits (89), Expect = 0.015 Identities = 39/167 (23%), Positives = 68/167 (40%), Gaps = 6/167 (3%) Query: 55 YYRLQEFALAAECYEQLGQLHPELEQYRLYQAQALYKACLYPEAT----RVAFLLLDNPA 110 Y+RL++FA+A L+ + + A + EA RV L +N Sbjct: 18 YFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFE 77 Query: 111 YHSRVLRLQAAIKYSEGDLPGSRSLVEQLLSGEGGEESGGDNETDG--QVNLGCLLYKEG 168 + + ++ A+ E P +V + GE + N+ + + G +KEG Sbjct: 78 ATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEG 137 Query: 169 QYEAACSKFSATLQASGYQPDLSYNLALAYYSSRQYASALKHIAEII 215 +YE A ++ + A G L N A+AY ++Y A K + I Sbjct: 138 KYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAI 184 >gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing protein) [Homo sapiens] Length = 543 Score = 38.1 bits (87), Expect = 0.026 Identities = 56/244 (22%), Positives = 102/244 (41%), Gaps = 50/244 (20%) Query: 386 LTEQLRRLTKQVQEARHNRDDEAIKK----AVNEYDETME---KYIPVLMAQAKIYWNLE 438 + E L KQ + + +D KK A+ YD+ E + + QA +Y+ Sbjct: 214 MEEDLPENKKQALKEKELGNDAYKKKDFDTALKHYDKAKELDPTNMTYITNQAAVYFEKG 273 Query: 439 NYPMVEKVFRKSVEFC--NDHDVWKLNVAHVL----FMQENKYKEAIGFYEPIVKKHYDN 492 +Y ++ K++E N D ++ A+ + +E KYK+AI FY + +H Sbjct: 274 DYNKCRELCEKAIEVGRENREDYRQIAKAYARIGNSYFKEEKYKDAIHFYNKSLAEHR-- 331 Query: 493 ILNVSAIVLANLCVSYIMTSQNEEAEELMRKIEKEEEQLSYDDPNRKMYHLCIVNLVIGT 552 + + + ++AE KI KE+E+L+Y +P+ L + G Sbjct: 332 --------------TPDVLKKCQQAE----KILKEQERLAYINPD-----LALEEKNKGN 368 Query: 553 LYCAKGNYEFGISRVIKSLEPYNKKLGTDTWYYAKR--CFLSLLENMSKHMIVIHDSVIQ 610 KG+Y + +++ K+ D Y+ R C+ LLE + + D + Sbjct: 369 ECFQKGDYPQAMKHYTEAI----KRNPKDAKLYSNRAACYTKLLE----FQLALKD--CE 418 Query: 611 ECVQ 614 EC+Q Sbjct: 419 ECIQ 422 Score = 30.8 bits (68), Expect = 4.2 Identities = 24/81 (29%), Positives = 37/81 (45%) Query: 27 YAEAVQLLGRELQRSPRSRAGLSLLGYCYYRLQEFALAAECYEQLGQLHPELEQYRLYQA 86 Y +A++ ++R+P+ S CY +L EF LA + E+ QL P + +A Sbjct: 376 YPQAMKHYTEAIKRNPKDAKLYSNRAACYTKLLEFQLALKDCEECIQLEPTFIKGYTRKA 435 Query: 87 QALYKACLYPEATRVAFLLLD 107 AL Y +A V LD Sbjct: 436 AALEAMKDYTKAMDVYQKALD 456 >gi|194306559 kinesin light chain 1 isoform 3 [Homo sapiens] Length = 618 Score = 37.0 bits (84), Expect = 0.059 Identities = 39/132 (29%), Positives = 59/132 (44%), Gaps = 13/132 (9%) Query: 462 LNVAHVLFMQENKYKEAIGFYE---PIVKKHYDNILNVSAIVLANLCVSYIMTSQNEEAE 518 LN+ +++ +NKYK+A I +K A L NL V Y + +EAE Sbjct: 258 LNILALVYRDQNKYKDAANLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAE 317 Query: 519 EL-MRKIEKEEEQLSYDDPN--RKMYHLCIVNLVIGTLYCAKGNYEFGISRVIKSLEPYN 575 L R +E E+ L D P+ +++ +L + L +G YE ++LE Y Sbjct: 318 PLCKRALEIREKVLGKDHPDVAKQLNNLAL-------LCQNQGKYEEVEYYYQRALEIYQ 370 Query: 576 KKLGTDTWYYAK 587 KLG D AK Sbjct: 371 TKLGPDDPNVAK 382 >gi|110735431 kinesin light chain 1 isoform 2 [Homo sapiens] Length = 573 Score = 37.0 bits (84), Expect = 0.059 Identities = 39/132 (29%), Positives = 59/132 (44%), Gaps = 13/132 (9%) Query: 462 LNVAHVLFMQENKYKEAIGFYE---PIVKKHYDNILNVSAIVLANLCVSYIMTSQNEEAE 518 LN+ +++ +NKYK+A I +K A L NL V Y + +EAE Sbjct: 258 LNILALVYRDQNKYKDAANLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAE 317 Query: 519 EL-MRKIEKEEEQLSYDDPN--RKMYHLCIVNLVIGTLYCAKGNYEFGISRVIKSLEPYN 575 L R +E E+ L D P+ +++ +L + L +G YE ++LE Y Sbjct: 318 PLCKRALEIREKVLGKDHPDVAKQLNNLAL-------LCQNQGKYEEVEYYYQRALEIYQ 370 Query: 576 KKLGTDTWYYAK 587 KLG D AK Sbjct: 371 TKLGPDDPNVAK 382 >gi|33620730 kinesin light chain 1 isoform 1 [Homo sapiens] Length = 560 Score = 37.0 bits (84), Expect = 0.059 Identities = 39/132 (29%), Positives = 59/132 (44%), Gaps = 13/132 (9%) Query: 462 LNVAHVLFMQENKYKEAIGFYE---PIVKKHYDNILNVSAIVLANLCVSYIMTSQNEEAE 518 LN+ +++ +NKYK+A I +K A L NL V Y + +EAE Sbjct: 258 LNILALVYRDQNKYKDAANLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAE 317 Query: 519 EL-MRKIEKEEEQLSYDDPN--RKMYHLCIVNLVIGTLYCAKGNYEFGISRVIKSLEPYN 575 L R +E E+ L D P+ +++ +L + L +G YE ++LE Y Sbjct: 318 PLCKRALEIREKVLGKDHPDVAKQLNNLAL-------LCQNQGKYEEVEYYYQRALEIYQ 370 Query: 576 KKLGTDTWYYAK 587 KLG D AK Sbjct: 371 TKLGPDDPNVAK 382 >gi|194353959 phosphoinositide-3-kinase, class 2 gamma polypeptide [Homo sapiens] Length = 1445 Score = 33.1 bits (74), Expect = 0.85 Identities = 24/79 (30%), Positives = 40/79 (50%), Gaps = 14/79 (17%) Query: 405 DDEAIKKAVNEYDETME----KYIPVLMAQAKIYWNLENYPMVEKVFRKSVEFCNDHDVW 460 D E K AV + D + +Y+P L+ K WNLE+ P+V+ + +S++ Sbjct: 734 DQEIRKVAVQQLDNLLNDELLEYLPQLVQAVKFEWNLES-PLVQLLLHRSLQ-------- 784 Query: 461 KLNVAHVLF-MQENKYKEA 478 + VAH L+ + +N EA Sbjct: 785 SIQVAHRLYWLLKNAENEA 803 >gi|21361356 translocase of outer mitochondrial membrane 34 [Homo sapiens] Length = 309 Score = 33.1 bits (74), Expect = 0.85 Identities = 17/53 (32%), Positives = 27/53 (50%) Query: 164 LYKEGQYEAACSKFSATLQASGYQPDLSYNLALAYYSSRQYASALKHIAEIIE 216 L K+G ++ A K+S +L S + N AL Y +QY A+K E ++ Sbjct: 203 LVKKGNHKKAIEKYSESLLCSNLESATYSNRALCYLVLKQYTEAVKDCTEALK 255 >gi|115430237 spectrin, beta, non-erythrocytic 4 isoform sigma1 [Homo sapiens] Length = 2564 Score = 33.1 bits (74), Expect = 0.85 Identities = 42/171 (24%), Positives = 68/171 (39%), Gaps = 9/171 (5%) Query: 58 LQEFALAAECYE-QLGQLHPELEQYRLYQAQALYKACLYPEAT----RVAFLLLDNPAYH 112 L+E AL AE + Q +LH E+ A EA R+ L D A+ Sbjct: 1042 LEEAALLAERFPAQAARLHQGAEELGAEWGALASAAQACGEAVAAAGRLQRFLHDLDAFL 1101 Query: 113 SRVLRLQAAIKYSEGDLPGSRSLVEQLLSGEGGEESGGDNETDGQVNLGCLLYKEGQYEA 172 ++R Q A SEG LP S + LL+ + D + + + E A Sbjct: 1102 DWLVRAQEAAGGSEGPLPNSLEEADALLARHAALKEEVDQREEDYARI--VAASEALLAA 1159 Query: 173 ACSKFSATLQASGYQP--DLSYNLALAYYSSRQYASALKHIAEIIERGIRQ 221 ++ L + P +L ++ L + +R+ A HI ++ R +RQ Sbjct: 1160 DGAELGPGLALDEWLPHLELGWHKLLGLWEARREALVQAHIYQLFLRDLRQ 1210 >gi|91825557 kinesin light chain 3 [Homo sapiens] Length = 504 Score = 32.7 bits (73), Expect = 1.1 Identities = 26/93 (27%), Positives = 40/93 (43%), Gaps = 4/93 (4%) Query: 449 KSVEFCNDHDVWKLNVAHVLFMQENKYKEAIGFYEPIVKKHYDNI---LNVSAIVLANLC 505 +S C+ LN+ +++ +NKYKEA ++ + A L NL Sbjct: 239 RSSGHCHPDVATMLNILALVYRDQNKYKEATDLLHDALQIREQTLGPEHPAVAATLNNLA 298 Query: 506 VSYIMTSQNEEAEEL-MRKIEKEEEQLSYDDPN 537 V Y + EAE L R +E E+ L D P+ Sbjct: 299 VLYGKRGRYREAEPLCQRALEIREKVLGADHPD 331 >gi|4557291 autoimmune regulator isoform 1 [Homo sapiens] Length = 545 Score = 32.3 bits (72), Expect = 1.4 Identities = 22/71 (30%), Positives = 37/71 (52%), Gaps = 4/71 (5%) Query: 118 LQAAIKYSEGDLPGSRSLVEQLLSGEGGEESGGDNETDGQVNLGCLLYKEGQYEAACSKF 177 +Q A+ S GD+PG+R VE +L + ESGG + + +G Y ++E + S Sbjct: 188 VQRAVAMSSGDVPGARGAVEGILI-QQVFESGGSKKC---IQVGGEFYTPSKFEDSGSGK 243 Query: 178 SATLQASGYQP 188 + +SG +P Sbjct: 244 NKARSSSGPKP 254 >gi|157502177 tetratricopeptide repeat domain 21A isoform 2 [Homo sapiens] Length = 1320 Score = 31.6 bits (70), Expect = 2.5 Identities = 30/100 (30%), Positives = 45/100 (45%), Gaps = 8/100 (8%) Query: 18 VYRLIRDARYAE---AVQLLGRELQRSPRSRAGLSLLGYCYYRLQEFALAAECYEQLGQL 74 +Y + + Y+E A +L R L+ P S L+ Y F + C E LG Sbjct: 505 LYLMAQVRYYSELENAQSILQRCLELDPASVDAHLLMCQIYLAQGNFGMCFHCLE-LGVS 563 Query: 75 HP----ELEQYRLYQAQALYKACLYPEATRVAFLLLDNPA 110 H + Y L +A+AL KA YPEA + +++ PA Sbjct: 564 HNFQVRDHPLYHLIKARALNKAGDYPEAIKTLKMVIKLPA 603 Score = 30.4 bits (67), Expect = 5.5 Identities = 18/62 (29%), Positives = 35/62 (56%), Gaps = 8/62 (12%) Query: 468 LFMQENKYKEAIGFYEPIVKKHYDNILNVSAIVLANLCVSYIMTSQNEEAE---ELMRKI 524 LF+ +N+ KEA+ +Y +K D + ++ I+L +I+ EEAE E ++++ Sbjct: 343 LFILKNQVKEALLWYSEAMKLDKDGMAGLTGIILC-----HILEGHLEEAEYRLEFLKEV 397 Query: 525 EK 526 +K Sbjct: 398 QK 399 >gi|31377634 guanylate binding protein 4 [Homo sapiens] Length = 640 Score = 31.2 bits (69), Expect = 3.2 Identities = 63/294 (21%), Positives = 113/294 (38%), Gaps = 63/294 (21%) Query: 286 DPVTLHNQALMNMDARPTEGFEKLQFLLQQNPFPPETFGNLLLLYCKYEYFDLAADVLAE 345 D T Q L +MD P E E+ FL+Q + F C Y + L E Sbjct: 252 DRPTNDKQYLNHMDEVPEENLER-HFLMQSDNF------------CSYIFTHAKTKTLRE 298 Query: 346 NAHLTYKFLTPYLYDFLDAL----ITCQTAPEEAFIKLDGLAGM----------LTEQLR 391 +T K L + ++DA+ + C A +L+ A + + +QLR Sbjct: 299 GIIVTGKRLGTLVVTYVDAINSGAVPCLENAVTALAQLENPAAVQRAADHYSQQMAQQLR 358 Query: 392 RLTKQVQE-----ARHNRDDEAIKKAVNEYDETME--KYIPVLMAQAKIYWNLENYPMVE 444 T +QE A R+ A+ + DE E K + + + K + L+N Sbjct: 359 LPTDTLQELLDVHAACEREAIAVFMEHSFKDENHEFQKKLVDTIEKKKGDFVLQNEEASA 418 Query: 445 KVFRKSVEFCNDH-------DVWKLNVAHVLFMQENKYKEAIGFYEPIVKKHY------D 491 K + ++ ++H ++ + H L+++E K E Y+ + +K Sbjct: 419 KYCQAELKRLSEHLTESILRGIFSVPGGHNLYLEEKKQVE--WDYKLVPRKGVKANEVLQ 476 Query: 492 NILNVSAIVLANLCVS--------------YIMTSQNEEAEELMRKIEKEEEQL 531 N L +V ++ S M E+ +EL+R+ +KE++Q+ Sbjct: 477 NFLQSQVVVEESILQSDKALTAGEKAIAAERAMKEAAEKEQELLREKQKEQQQM 530 >gi|157502179 tetratricopeptide repeat domain 21A isoform 1 [Homo sapiens] Length = 1321 Score = 31.2 bits (69), Expect = 3.2 Identities = 27/85 (31%), Positives = 38/85 (44%), Gaps = 5/85 (5%) Query: 30 AVQLLGRELQRSPRSRAGLSLLGYCYYRLQEFALAAECYEQLGQLHP----ELEQYRLYQ 85 A +L R L+ P S L+ Y F + C E LG H + Y L + Sbjct: 521 AQSILQRCLELDPASVDAHLLMCQIYLAQGNFGMCFHCLE-LGVSHNFQVRDHPLYHLIK 579 Query: 86 AQALYKACLYPEATRVAFLLLDNPA 110 A+AL KA YPEA + +++ PA Sbjct: 580 ARALNKAGDYPEAIKTLKMVIKLPA 604 Score = 30.4 bits (67), Expect = 5.5 Identities = 18/62 (29%), Positives = 35/62 (56%), Gaps = 8/62 (12%) Query: 468 LFMQENKYKEAIGFYEPIVKKHYDNILNVSAIVLANLCVSYIMTSQNEEAE---ELMRKI 524 LF+ +N+ KEA+ +Y +K D + ++ I+L +I+ EEAE E ++++ Sbjct: 343 LFILKNQVKEALLWYSEAMKLDKDGMAGLTGIILC-----HILEGHLEEAEYRLEFLKEV 397 Query: 525 EK 526 +K Sbjct: 398 QK 399 >gi|21450645 tetratricopeptide repeat domain 16 [Homo sapiens] Length = 873 Score = 31.2 bits (69), Expect = 3.2 Identities = 43/195 (22%), Positives = 72/195 (36%), Gaps = 26/195 (13%) Query: 30 AVQLLGRELQRSPRSRAGLSLLGYCYYRLQEFALAAECYEQLGQLHPELEQYRLYQAQAL 89 A+Q + R ++ +P + G Y RLQEF A E + ++ + E ++ + QAQ Sbjct: 270 ALQRINRAIENNPLDPSLFLFRGTMYRRLQEFDGAVEDFLKVLDMVTEDQEDMVRQAQ-- 327 Query: 90 YKACLYPEATRVAFLLLDNPAYHSRVLRLQAAIKYSEGDLPGSRSLVEQLLSGEGGEESG 149 R L ++ A H Y +G L+ + L E E+ Sbjct: 328 ----------RQLLLTYNDFAVHC----------YRQGAYQEGVLLLNKALRDEQQEKGL 367 Query: 150 GDNETDGQVNLGCLLYKEGQYEAACSKFSATLQASGYQPDLSYNLALAYYSSRQYASALK 209 N D LG L + E Y+ A + A+ L + +Q+ A Sbjct: 368 YINRGDCFFQLGNLAFAEADYQQALALSPQDEGANTRMGLLQEKMGFCEQRRKQFQKAEN 427 Query: 210 HIAEIIERGIRQHPE 224 H + IR +P+ Sbjct: 428 HFS----TAIRHNPQ 438 >gi|56119110 family with sequence similarity 13, member A1 isoform a [Homo sapiens] Length = 1023 Score = 30.8 bits (68), Expect = 4.2 Identities = 18/62 (29%), Positives = 32/62 (51%), Gaps = 3/62 (4%) Query: 585 YAKRCFLSLLENMSKHMIV-IHDSVIQECVQFLGHCELYGTNIPAVIE--QPLEEERMHV 641 ++ RCFL E+ + I + D + +C Q G L+ +IP ++E Q + EE+ + Sbjct: 906 FSARCFLDQFEDDADGFISPMDDKIPSKCSQDTGLSNLHAASIPELLEHLQEMREEKKRI 965 Query: 642 GK 643 K Sbjct: 966 RK 967 >gi|62865869 family with sequence similarity 13, member A1 isoform b [Homo sapiens] Length = 697 Score = 30.8 bits (68), Expect = 4.2 Identities = 18/62 (29%), Positives = 32/62 (51%), Gaps = 3/62 (4%) Query: 585 YAKRCFLSLLENMSKHMIV-IHDSVIQECVQFLGHCELYGTNIPAVIE--QPLEEERMHV 641 ++ RCFL E+ + I + D + +C Q G L+ +IP ++E Q + EE+ + Sbjct: 580 FSARCFLDQFEDDADGFISPMDDKIPSKCSQDTGLSNLHAASIPELLEHLQEMREEKKRI 639 Query: 642 GK 643 K Sbjct: 640 RK 641 >gi|22749211 transmembrane and tetratricopeptide repeat containing 2 [Homo sapiens] Length = 836 Score = 30.8 bits (68), Expect = 4.2 Identities = 42/196 (21%), Positives = 71/196 (36%), Gaps = 29/196 (14%) Query: 159 NLGCLLYKEGQYEAACSKFSATLQASGYQPDLSYNLALAYYSSRQYASALKHIAEIIERG 218 NLG +L + + A S + L D+ YNL L + ++A AL + + Sbjct: 498 NLGNVLKSQSKISEAESAYRNALYYRSNMADMLYNLGLLLQENSRFAEALHY----YKLA 553 Query: 219 IRQHPELGVGMTTEGFDVRSVGNTLVLHQTAL----VEAFNLK----------------A 258 I P L G + + G T +T L + NLK Sbjct: 554 IGSRPTLASAYLNTGIILMNQGRTEEARRTFLKCSEIPDENLKDPHAHKSSVTSCLYNLG 613 Query: 259 AIEYQLRNYEVAQETLTDMPPRAEEELDPVTLHN---QALMNMDARPTEGFEKLQFLLQQ 315 + ++ +YE A + + + P +L+N +A M + P ++ L + Sbjct: 614 KLYHEQGHYEEALSVYKEAIQKMPRQFAPQSLYNMMGEAYMRLSKLPEAEHWYMESLRSK 673 Query: 316 NPFPPE--TFGNLLLL 329 P T+G LL L Sbjct: 674 TDHIPAHLTYGKLLAL 689 >gi|41871960 kinesin-like 8 isoform b [Homo sapiens] Length = 637 Score = 30.8 bits (68), Expect = 4.2 Identities = 33/126 (26%), Positives = 55/126 (43%), Gaps = 13/126 (10%) Query: 462 LNVAHVLFMQENKYKEAIGFYEPIVKKHYDNI---LNVSAIVLANLCVSYIMTSQNEEAE 518 LN+ +++ +NKYKEA + + A L NL V Y + +EAE Sbjct: 274 LNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVAATLNNLAVLYGKRGKYKEAE 333 Query: 519 EL-MRKIEKEEEQLSYDDPN--RKMYHLCIVNLVIGTLYCAKGNYEFGISRVIKSLEPYN 575 L R +E E+ L + P+ +++ +L + L +G YE ++L Y Sbjct: 334 PLCQRALEIREKVLGTNHPDVAKQLNNLAL-------LCQNQGKYEAVERYYQRALAIYE 386 Query: 576 KKLGTD 581 +LG D Sbjct: 387 GQLGPD 392 >gi|41871955 kinesin-like 8 isoform a [Homo sapiens] Length = 619 Score = 30.8 bits (68), Expect = 4.2 Identities = 33/126 (26%), Positives = 55/126 (43%), Gaps = 13/126 (10%) Query: 462 LNVAHVLFMQENKYKEAIGFYEPIVKKHYDNI---LNVSAIVLANLCVSYIMTSQNEEAE 518 LN+ +++ +NKYKEA + + A L NL V Y + +EAE Sbjct: 256 LNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVAATLNNLAVLYGKRGKYKEAE 315 Query: 519 EL-MRKIEKEEEQLSYDDPN--RKMYHLCIVNLVIGTLYCAKGNYEFGISRVIKSLEPYN 575 L R +E E+ L + P+ +++ +L + L +G YE ++L Y Sbjct: 316 PLCQRALEIREKVLGTNHPDVAKQLNNLAL-------LCQNQGKYEAVERYYQRALAIYE 368 Query: 576 KKLGTD 581 +LG D Sbjct: 369 GQLGPD 374 >gi|41871946 kinesin-like 8 isoform a [Homo sapiens] Length = 619 Score = 30.8 bits (68), Expect = 4.2 Identities = 33/126 (26%), Positives = 55/126 (43%), Gaps = 13/126 (10%) Query: 462 LNVAHVLFMQENKYKEAIGFYEPIVKKHYDNI---LNVSAIVLANLCVSYIMTSQNEEAE 518 LN+ +++ +NKYKEA + + A L NL V Y + +EAE Sbjct: 256 LNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVAATLNNLAVLYGKRGKYKEAE 315 Query: 519 EL-MRKIEKEEEQLSYDDPN--RKMYHLCIVNLVIGTLYCAKGNYEFGISRVIKSLEPYN 575 L R +E E+ L + P+ +++ +L + L +G YE ++L Y Sbjct: 316 PLCQRALEIREKVLGTNHPDVAKQLNNLAL-------LCQNQGKYEAVERYYQRALAIYE 368 Query: 576 KKLGTD 581 +LG D Sbjct: 369 GQLGPD 374 >gi|25952122 Bardet-Biedl syndrome 4 [Homo sapiens] Length = 519 Score = 30.4 bits (67), Expect = 5.5 Identities = 16/57 (28%), Positives = 28/57 (49%) Query: 159 NLGCLLYKEGQYEAACSKFSATLQASGYQPDLSYNLALAYYSSRQYASALKHIAEII 215 N+G + + +Y AA S + + + YNL L + + +QYASA ++ I Sbjct: 275 NIGMCFFGKKKYVAAISCLKRANYLAPFDWKILYNLGLVHLTMQQYASAFHFLSAAI 331 >gi|4557495 cleavage stimulation factor subunit 3 isoform 1 [Homo sapiens] Length = 717 Score = 30.4 bits (67), Expect = 5.5 Identities = 36/150 (24%), Positives = 73/150 (48%), Gaps = 20/150 (13%) Query: 383 AGMLTEQLRRLTKQVQEARHNRDDEAI--KKAVNEYDETMEKYIPVLMAQ---AKIYWNL 437 A + E++++ K+++E ++ D +I ++A N+ + K L+AQ + +W L Sbjct: 11 AEYVPEKVKKAEKKLEENPYDLDAWSILIREAQNQPIDKARKTYERLVAQFPSSGRFWKL 70 Query: 438 --------ENYPMVEKVFRKSVEFCNDHDVWKLNVAHVLFMQENKYKEAIGFYEPIVKKH 489 +NY VEK+F++ + D+WK ++ +++E K K + Y+ + + Sbjct: 71 YIEAEIKAKNYDKVEKLFQRCLMKVLHIDLWK---CYLSYVRETKGK--LPSYKEKMAQA 125 Query: 490 YDNILNV--SAIVLANLCVSYIMTSQNEEA 517 YD L+ I+ + V YI + EA Sbjct: 126 YDFALDKIGMEIMSYQIWVDYINFLKGVEA 155 >gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens] Length = 2481 Score = 30.0 bits (66), Expect = 7.2 Identities = 61/253 (24%), Positives = 92/253 (36%), Gaps = 52/253 (20%) Query: 34 LGRELQRSPRSRAGLSLLGYCYYRLQEFALAAECYEQLGQLHPELEQYRLYQAQALYKAC 93 + REL+ LS LG + E+ AA YEQ +L P+L+ + K C Sbjct: 583 IARELRDIQSEARALSNLGNFHCSRGEYVQAAPYYEQYLRLAPDLQ-----DMEGEGKVC 637 Query: 94 LYPEATRVAFLLLDNPAY-HSRVLRLQAAIKYSEGDLPGSRSLVEQLLSGEGGEESGGDN 152 N Y H + Q A+KY E DL ++ L ++L + Sbjct: 638 -------------HNLGYAHYCLGNYQEAVKYYEQDLALAKDLHDKL------------S 672 Query: 153 ETDGQVNLGCLLYKEGQYEAACSKFSATLQASGYQPDLSYNLALAYYSSRQYAS--ALKH 210 + NLG F A L S + Y L+LA + A AL + Sbjct: 673 QAKAYCNLGL-------------AFKALLNFSKAEECQKYLLSLAQSLNNSQAKFRALGN 719 Query: 211 IAEII-----ERGIRQHPELGVGMTTEGFDVRSVGNTLVLHQTALVEAFNLKAAIEYQLR 265 + +I G + E +G+ + D R + TA A+ Y + Sbjct: 720 LGDIFICKKDINGAIKFYEQQLGLAHQVKDRRLEASAYAALGTAYRMIQKYDKALGYHTQ 779 Query: 266 NYEVAQETLTDMP 278 EV QE L+D+P Sbjct: 780 ELEVYQE-LSDLP 791 >gi|24415404 MDN1, midasin homolog [Homo sapiens] Length = 5596 Score = 30.0 bits (66), Expect = 7.2 Identities = 13/38 (34%), Positives = 23/38 (60%) Query: 101 VAFLLLDNPAYHSRVLRLQAAIKYSEGDLPGSRSLVEQ 138 V F++LDNP+ +L ++ I G++P RS +E+ Sbjct: 5523 VIFVVLDNPSSRDSILDIKVPIFKGPGEMPEIRSYMEE 5560 >gi|148806872 lupus brain antigen 1 [Homo sapiens] Length = 2375 Score = 30.0 bits (66), Expect = 7.2 Identities = 27/101 (26%), Positives = 44/101 (43%), Gaps = 8/101 (7%) Query: 27 YAEAVQLLGRELQRSPRSRAGLSLLGYCYYRLQEFALAAECYEQLGQLHPELEQY---RL 83 YA+ QL + +R + R Y Y R Q + A C+EQ+ + L+ Y L Sbjct: 1229 YAKEFQLSAQLCERLGKIRDA----AYFYKRSQCYKDAFRCFEQIQEFDLALKMYCQEEL 1284 Query: 84 YQAQALYKACLYPEATRVAFLLLDNPAYHSRVLRLQAAIKY 124 ++ +A Y E + L + +Y + L+AA KY Sbjct: 1285 FE-EAAIAVEKYEEMLKTKTLPISKLSYSASQFYLEAAAKY 1324 >gi|37622896 LON peptidase N-terminal domain and ring finger 3 isoform 2 [Homo sapiens] Length = 718 Score = 30.0 bits (66), Expect = 7.2 Identities = 33/122 (27%), Positives = 53/122 (43%), Gaps = 5/122 (4%) Query: 127 GDLPGSRSLVEQLLSGEGGEESGGDNETDGQVNLGCLLYKEGQYEAACSKFSATLQASGY 186 G P V +LSG G+ G + G LY+E Q EAA K++ ++ + Sbjct: 216 GQQPPPPLRVNVVLSGLLGKLFPGPARASQLRHEGNRLYRERQVEAALLKYNEAVKLAPN 275 Query: 187 QPDLSYNLALAYYSSRQYASALKHIAEII----ERGIRQHPELGVGMTTEGFDVRSVGNT 242 L N + Y++ + +AL H AEI G + + EL + E R G++ Sbjct: 276 DHLLYSNRSQIYFTLESHENAL-HDAEIACKLRPMGFKDNLELPHCSSQEEAAARGDGSS 334 Query: 243 LV 244 L+ Sbjct: 335 LM 336 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.319 0.136 0.396 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 24,368,683 Number of Sequences: 37866 Number of extensions: 1067890 Number of successful extensions: 3319 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 9 Number of HSP's successfully gapped in prelim test: 30 Number of HSP's that attempted gapping in prelim test: 3282 Number of HSP's gapped (non-prelim): 65 length of query: 665 length of database: 18,247,518 effective HSP length: 109 effective length of query: 556 effective length of database: 14,120,124 effective search space: 7850788944 effective search space used: 7850788944 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.