Guide to the Human Genome
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Search of human proteins with 14211873

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|14211873 emopamil binding related protein, delta8-delta7
sterol isomerase [Homo sapiens]
         (206 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|14211873 emopamil binding related protein, delta8-delta7 ster...   433   e-122
gi|5729810 emopamil binding protein (sterol isomerase) [Homo sap...    90   1e-18
gi|10092643 Yip1 domain family, member 1 [Homo sapiens]                30   1.9  
gi|240120161 G protein-coupled receptor 144 [Homo sapiens]             28   5.5  
gi|57165371 G protein-coupled receptor 61 [Homo sapiens]               28   7.2  
gi|40807489 egf-like module containing, mucin-like, hormone rece...    28   7.2  
gi|14043066 angiotensin II receptor, type 1 [Homo sapiens]             27   9.4  
gi|14043064 angiotensin II receptor, type 1 [Homo sapiens]             27   9.4  
gi|14043062 angiotensin II receptor, type 1 [Homo sapiens]             27   9.4  
gi|6715583 angiotensin II receptor, type 1 [Homo sapiens]              27   9.4  
gi|4501997 angiotensin II receptor, type 1 [Homo sapiens]              27   9.4  

>gi|14211873 emopamil binding related protein, delta8-delta7 sterol
           isomerase [Homo sapiens]
          Length = 206

 Score =  433 bits (1114), Expect = e-122
 Identities = 206/206 (100%), Positives = 206/206 (100%)

Query: 1   MGAEWELGAEAGGSLLLCAALLAAGCALGLRLGRGQGAADRGALIWLCYDALVHFALEGP 60
           MGAEWELGAEAGGSLLLCAALLAAGCALGLRLGRGQGAADRGALIWLCYDALVHFALEGP
Sbjct: 1   MGAEWELGAEAGGSLLLCAALLAAGCALGLRLGRGQGAADRGALIWLCYDALVHFALEGP 60

Query: 61  FVYLSLVGNVANSDGLIASLWKEYGKADARWVYFDPTIVSVEILTVALDGSLALFLIYAI 120
           FVYLSLVGNVANSDGLIASLWKEYGKADARWVYFDPTIVSVEILTVALDGSLALFLIYAI
Sbjct: 61  FVYLSLVGNVANSDGLIASLWKEYGKADARWVYFDPTIVSVEILTVALDGSLALFLIYAI 120

Query: 121 VKEKYYRHFLQITLCVCELYGCWMTFLPEWLTRSPNLNTSNWLYCWLYLFFFNGVWVLIP 180
           VKEKYYRHFLQITLCVCELYGCWMTFLPEWLTRSPNLNTSNWLYCWLYLFFFNGVWVLIP
Sbjct: 121 VKEKYYRHFLQITLCVCELYGCWMTFLPEWLTRSPNLNTSNWLYCWLYLFFFNGVWVLIP 180

Query: 181 GLLLWQSWLELKKMHQKETSSVKKFQ 206
           GLLLWQSWLELKKMHQKETSSVKKFQ
Sbjct: 181 GLLLWQSWLELKKMHQKETSSVKKFQ 206


>gi|5729810 emopamil binding protein (sterol isomerase) [Homo
           sapiens]
          Length = 230

 Score = 90.1 bits (222), Expect = 1e-18
 Identities = 54/172 (31%), Positives = 91/172 (52%), Gaps = 10/172 (5%)

Query: 15  LLLCAALLAAGCALGLRLGRGQGAADRGALIWLCYDALVHFALEGPFV--YLSLVGNVAN 72
           +L+    L +G A  + LG  +    R +L W      +H  +EG FV  Y  L+G+ A 
Sbjct: 41  VLVVTTWLLSGRAAVVPLGTWR----RLSLCWFAVCGFIHLVIEGWFVLYYEDLLGDQA- 95

Query: 73  SDGLIASLWKEYGKADARWVYFDPTIVSVEILTVALDGSLALFLIYAIVKEKYYRHFLQI 132
               ++ LWKEY K D+R++  D   V +E +T  L G L+L+++ A +++   R  LQ+
Sbjct: 96  ---FLSQLWKEYAKGDSRYILGDNFTVCMETITACLWGPLSLWVVIAFLRQHPLRFILQL 152

Query: 133 TLCVCELYGCWMTFLPEWLTRSPNLNTSNWLYCWLYLFFFNGVWVLIPGLLL 184
            + V ++YG  + FL E      +    + LY W Y  F N +W+++PG+L+
Sbjct: 153 VVSVGQIYGDVLYFLTEHRDGFQHGELGHPLYFWFYFVFMNALWLVLPGVLV 204


>gi|10092643 Yip1 domain family, member 1 [Homo sapiens]
          Length = 306

 Score = 29.6 bits (65), Expect = 1.9
 Identities = 20/94 (21%), Positives = 44/94 (46%), Gaps = 6/94 (6%)

Query: 98  IVSVEILTVALDGSLALFLIYAIVKEKYY-RHFLQITLCVCELYG-CWMTFLPEW----L 151
           I +  +  +A+ G+L+ FLI+   K  +Y   F ++++    +Y   W+  L  W     
Sbjct: 126 ICATLVFAIAISGNLSNFLIHLGEKTYHYVPEFRKVSIAATIIYAYAWLVPLALWGFLMW 185

Query: 152 TRSPNLNTSNWLYCWLYLFFFNGVWVLIPGLLLW 185
             S  +N  ++ +  +   +   +++ IP  +LW
Sbjct: 186 RNSKVMNIVSYSFLEIVCVYGYSLFIYIPTAILW 219


>gi|240120161 G protein-coupled receptor 144 [Homo sapiens]
          Length = 963

 Score = 28.1 bits (61), Expect = 5.5
 Identities = 21/80 (26%), Positives = 34/80 (42%), Gaps = 3/80 (3%)

Query: 107 ALDGSLALFLIYAIVKEKYYRHFLQITLCVCELYGCWMTFLPEWLTRSPNLNTSNWLYCW 166
           AL  +  LFL+  + K +       +T  +    G  MT   EW  ++  +         
Sbjct: 672 ALTTTFLLFLVAGVPKSERTTVHKNLTFSLASAEGFLMT--SEW-AKANEVACVAVTVAM 728

Query: 167 LYLFFFNGVWVLIPGLLLWQ 186
            +LF     W+L+ GLLLW+
Sbjct: 729 HFLFLVAFSWMLVEGLLLWR 748


>gi|57165371 G protein-coupled receptor 61 [Homo sapiens]
          Length = 451

 Score = 27.7 bits (60), Expect = 7.2
 Identities = 27/98 (27%), Positives = 45/98 (45%), Gaps = 24/98 (24%)

Query: 111 SLALFLIYAIVKEKYY------RHFLQITLCVCE--LYGCWMTFLP----------EWLT 152
           SLA+  + AI  E+YY      R+ +++TL +    L G W+  L            W  
Sbjct: 127 SLAILSVSAINVERYYYVVHPMRYEVRMTLGLVASVLVGVWVKALAMASVPVLGRVSWEE 186

Query: 153 RSPN------LNTSNWLYCWLYLFFFNGVWVLIPGLLL 184
            +P+      L  S+  YC L++  F  ++ L+P LL+
Sbjct: 187 GAPSVPPGCSLQWSHSAYCQLFVVVFAVLYFLLPLLLI 224


>gi|40807489 egf-like module containing, mucin-like, hormone
           receptor-like sequence 1 [Homo sapiens]
          Length = 886

 Score = 27.7 bits (60), Expect = 7.2
 Identities = 27/111 (24%), Positives = 50/111 (45%), Gaps = 15/111 (13%)

Query: 99  VSVEILTVALDGSLALFLIYAIVKEKYYRHFLQITLCVCELYGCWMTFLPEWLTRSPNLN 158
           V + I  V L  ++A FL+   ++   +  +L + LCVC L       L + L  +    
Sbjct: 608 VGIIISLVCLVLAIATFLLCRSIRN--HNTYLHLHLCVCLL-------LAKTLFLAGIHK 658

Query: 159 TSNWLYCWL------YLFFFNGVWVLIPGLLLWQSWLELKKMHQKETSSVK 203
           T N + C +      YLF     W+L+  ++L+     LK ++   + ++K
Sbjct: 659 TDNKMGCAIIAGFLHYLFLACFFWMLVEAVILFLMVRNLKVVNYFSSRNIK 709


>gi|14043066 angiotensin II receptor, type 1 [Homo sapiens]
          Length = 359

 Score = 27.3 bits (59), Expect = 9.4
 Identities = 15/55 (27%), Positives = 26/55 (47%), Gaps = 2/55 (3%)

Query: 96  PTIVSVEILTVALDGSLALFLIYAIVKEKYYRHFLQITLCVCELYGCWMTFLPEW 150
           PT+ S+  +      SL + +IY  +K K       + L + +L  C++  LP W
Sbjct: 32  PTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADL--CFLLTLPLW 84


>gi|14043064 angiotensin II receptor, type 1 [Homo sapiens]
          Length = 359

 Score = 27.3 bits (59), Expect = 9.4
 Identities = 15/55 (27%), Positives = 26/55 (47%), Gaps = 2/55 (3%)

Query: 96  PTIVSVEILTVALDGSLALFLIYAIVKEKYYRHFLQITLCVCELYGCWMTFLPEW 150
           PT+ S+  +      SL + +IY  +K K       + L + +L  C++  LP W
Sbjct: 32  PTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADL--CFLLTLPLW 84


>gi|14043062 angiotensin II receptor, type 1 [Homo sapiens]
          Length = 359

 Score = 27.3 bits (59), Expect = 9.4
 Identities = 15/55 (27%), Positives = 26/55 (47%), Gaps = 2/55 (3%)

Query: 96  PTIVSVEILTVALDGSLALFLIYAIVKEKYYRHFLQITLCVCELYGCWMTFLPEW 150
           PT+ S+  +      SL + +IY  +K K       + L + +L  C++  LP W
Sbjct: 32  PTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADL--CFLLTLPLW 84


>gi|6715583 angiotensin II receptor, type 1 [Homo sapiens]
          Length = 359

 Score = 27.3 bits (59), Expect = 9.4
 Identities = 15/55 (27%), Positives = 26/55 (47%), Gaps = 2/55 (3%)

Query: 96  PTIVSVEILTVALDGSLALFLIYAIVKEKYYRHFLQITLCVCELYGCWMTFLPEW 150
           PT+ S+  +      SL + +IY  +K K       + L + +L  C++  LP W
Sbjct: 32  PTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADL--CFLLTLPLW 84


>gi|4501997 angiotensin II receptor, type 1 [Homo sapiens]
          Length = 359

 Score = 27.3 bits (59), Expect = 9.4
 Identities = 15/55 (27%), Positives = 26/55 (47%), Gaps = 2/55 (3%)

Query: 96  PTIVSVEILTVALDGSLALFLIYAIVKEKYYRHFLQITLCVCELYGCWMTFLPEW 150
           PT+ S+  +      SL + +IY  +K K       + L + +L  C++  LP W
Sbjct: 32  PTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADL--CFLLTLPLW 84


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.326    0.141    0.481 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,124,547
Number of Sequences: 37866
Number of extensions: 336191
Number of successful extensions: 899
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 890
Number of HSP's gapped (non-prelim): 16
length of query: 206
length of database: 18,247,518
effective HSP length: 97
effective length of query: 109
effective length of database: 14,574,516
effective search space: 1588622244
effective search space used: 1588622244
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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