Guide to the Human Genome
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Name: MTHFD2 Sequence: fasta or formatted (350aa) NCBI GI: 94721354
Description:

methylenetetrahydrofolate dehydrogenase 2 precursor

Referenced in:

Mitochondria
Vitamin Pathways, Coenzymes, and 1-Carbon Metabolism

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             9.7         34           3
 C cysteine            0.9          3           1
 D aspartate           4.6         16           2
 E glutamate           6.0         21           3
 F phenylalanine       0.9          3           1
 G glycine             7.1         25           2
 H histidine           3.1         11           1
 I isoleucine          7.4         26           2
 K lysine              6.3         22           2
 L leucine             9.4         33           2
 M methionine          3.1         11           1
 N asparagine          5.1         18           2
 P proline             5.7         20           1
 Q glutamine           2.6          9           2
 R arginine            5.4         19           2
 S serine              5.1         18           1
 T threonine           4.9         17           1
 V valine             10.6         37           3
 W tryptophan          0.9          3           1
 Y tyrosine            1.1          4           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   methylenetetrahydrofolate dehydrogenase 2 precursor ... 
MTHFD2L               0.667   methylenetetrahydrofolate dehydrogenase 2-like [Hom...
MTHFD1                0.259   methylenetetrahydrofolate dehydrogenase 1 
MTHFD1L               0.071   methylenetetrahydrofolate dehydrogenase (NADP+ depen...
APPL2                 0.015   adaptor protein, phosphotyrosine interaction, PH dom...
TBC1D4                0.009   TBC1 domain family, member 4 
MTO1                  0.006   mitochondrial translation optimization 1 homolog is...
MTO1                  0.006   mitochondrial translation optimization 1 homolog iso...
ANXA11                0.006   annexin A11 
MTO1                  0.006   mitochondrial translation optimization 1 homolog iso...
ANXA11                0.006   annexin A11 
ANXA11                0.006   annexin A11 
PIK3CB                0.006   catalytic phosphatidylinositol 3-kinase beta 
LOC100128993          0.006   PREDICTED: hypothetical protein LOC100128993 
LOC100128993          0.006   PREDICTED: hypothetical protein LOC100128993 
LOC100128993          0.006   PREDICTED: hypothetical protein LOC100128993 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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