Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 93204881
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|93204881 Rab interacting lysosomal protein [Homo sapiens]
(401 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|93204881 Rab interacting lysosomal protein [Homo sapiens] 795 0.0
gi|195947382 Rab interacting lysosomal protein-like 1 [Homo sapi... 130 3e-30
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 52 1e-06
gi|191252814 RIMS binding protein 3B [Homo sapiens] 52 1e-06
gi|191252806 RIMS binding protein 3C [Homo sapiens] 52 1e-06
gi|153792195 DKFZP434H0735 protein [Homo sapiens] 52 1e-06
gi|194578923 sperm associated antigen 9 isoform 1 [Homo sapiens] 50 3e-06
gi|27436920 sperm associated antigen 9 isoform 3 [Homo sapiens] 50 3e-06
gi|94557295 mitogen-activated protein kinase 8 interacting prote... 50 3e-06
gi|94557297 mitogen-activated protein kinase 8 interacting prote... 50 3e-06
gi|91208420 bassoon protein [Homo sapiens] 50 4e-06
gi|111955084 5-azacytidine induced 1 isoform a [Homo sapiens] 50 4e-06
gi|115648142 centrosomal protein 164kDa [Homo sapiens] 50 5e-06
gi|239745099 PREDICTED: similar to Golgin subfamily A member 8-l... 49 6e-06
gi|148746195 trichohyalin [Homo sapiens] 49 6e-06
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 49 6e-06
gi|210032790 hypothetical protein LOC27146 [Homo sapiens] 49 6e-06
gi|46592991 GRIP1 associated protein 1 isoform 1 [Homo sapiens] 49 8e-06
gi|194578896 golgi autoantigen, golgin subfamily a, 8E [Homo sap... 49 1e-05
gi|239745111 PREDICTED: Golgin subfamily A member 8-like protein... 48 1e-05
gi|56549694 enabled homolog isoform a [Homo sapiens] 48 2e-05
gi|39930375 enabled homolog isoform b [Homo sapiens] 48 2e-05
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] 48 2e-05
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 48 2e-05
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] 48 2e-05
gi|113425137 PREDICTED: similar to Golgin subfamily A member 8-l... 48 2e-05
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens] 47 2e-05
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 47 2e-05
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 47 2e-05
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 47 2e-05
>gi|93204881 Rab interacting lysosomal protein [Homo sapiens]
Length = 401
Score = 795 bits (2053), Expect = 0.0
Identities = 401/401 (100%), Positives = 401/401 (100%)
Query: 1 MEPRRAAPGVPGWGSREAAGSASAAELVYHLAGALGTELQDLARRFGPEAAAGLVPLVVR 60
MEPRRAAPGVPGWGSREAAGSASAAELVYHLAGALGTELQDLARRFGPEAAAGLVPLVVR
Sbjct: 1 MEPRRAAPGVPGWGSREAAGSASAAELVYHLAGALGTELQDLARRFGPEAAAGLVPLVVR 60
Query: 61 ALELLEQAAVGPAPDSLQVSAQPAEQELRRLREENERLRRELRAGPQEERALLRQLKEVT 120
ALELLEQAAVGPAPDSLQVSAQPAEQELRRLREENERLRRELRAGPQEERALLRQLKEVT
Sbjct: 61 ALELLEQAAVGPAPDSLQVSAQPAEQELRRLREENERLRRELRAGPQEERALLRQLKEVT 120
Query: 121 DRQRDELRAHNRDLRQRGQETEALQEQLQRLLLVNAELRHKLAAMQTQLRAAQDRERERQ 180
DRQRDELRAHNRDLRQRGQETEALQEQLQRLLLVNAELRHKLAAMQTQLRAAQDRERERQ
Sbjct: 121 DRQRDELRAHNRDLRQRGQETEALQEQLQRLLLVNAELRHKLAAMQTQLRAAQDRERERQ 180
Query: 181 QPGEAATPQAKERARGQAGRPGHQHGQEPEWATAGAGAPGNPEDPAEAAQQLGRPSEAGQ 240
QPGEAATPQAKERARGQAGRPGHQHGQEPEWATAGAGAPGNPEDPAEAAQQLGRPSEAGQ
Sbjct: 181 QPGEAATPQAKERARGQAGRPGHQHGQEPEWATAGAGAPGNPEDPAEAAQQLGRPSEAGQ 240
Query: 241 CRFSREEFEQILQERNELKAKVFLLKEELAYFQRELLTDHRVPGLLLEAMKVAVRKQRKK 300
CRFSREEFEQILQERNELKAKVFLLKEELAYFQRELLTDHRVPGLLLEAMKVAVRKQRKK
Sbjct: 241 CRFSREEFEQILQERNELKAKVFLLKEELAYFQRELLTDHRVPGLLLEAMKVAVRKQRKK 300
Query: 301 IKAKMLGTPEEAESSEDEAGPWILLSDDKGDHPPPPESKIQSFFGLWYRGKAESSEDETS 360
IKAKMLGTPEEAESSEDEAGPWILLSDDKGDHPPPPESKIQSFFGLWYRGKAESSEDETS
Sbjct: 301 IKAKMLGTPEEAESSEDEAGPWILLSDDKGDHPPPPESKIQSFFGLWYRGKAESSEDETS 360
Query: 361 SPAPSKLGGEEEAQPQSPAPDPPCSALHEHLCLGASAAPEA 401
SPAPSKLGGEEEAQPQSPAPDPPCSALHEHLCLGASAAPEA
Sbjct: 361 SPAPSKLGGEEEAQPQSPAPDPPCSALHEHLCLGASAAPEA 401
>gi|195947382 Rab interacting lysosomal protein-like 1 [Homo
sapiens]
Length = 403
Score = 130 bits (326), Expect = 3e-30
Identities = 106/339 (31%), Positives = 166/339 (48%), Gaps = 78/339 (23%)
Query: 14 GSREAAGSA---SAAEL----VYHLAGALGTELQDLARRFGPEAAAGLVPLVVRALELLE 66
GS AA SA + AEL VY +A +G E + + + G EA A L+P VVR LE+LE
Sbjct: 6 GSALAAESALEKNVAELTVMDVYDIASLVGHEFERVIDQHGCEAIARLMPKVVRVLEILE 65
Query: 67 QAA----VGPAPDSLQVS--------------------------------AQPAEQELRR 90
V P D L++ AQ ++ +
Sbjct: 66 VLVSRHHVAPELDELRLELDRLRLERMDRIEKERKHQKELELVEDVWRGEAQDLLSQIAQ 125
Query: 91 LREENERLRREL---------------RAGPQEERALLRQLKEVTDRQRDELRAHNRDLR 135
L+EEN++L L + ER ++++LKEV D+QRDE+RA +R+L
Sbjct: 126 LQEENKQLMTNLSHKDVNFSEEEFQKHEGMSERERQVMKKLKEVVDKQRDEIRAKDRELG 185
Query: 136 QRGQETEALQEQLQRLLLVNAELRHKLAAMQTQLRA--------AQDRERERQQPG--EA 185
+ ++ EALQ+Q RL+ +N +LRH++ ++ Q +A D + + Q+ G A
Sbjct: 186 LKNEDVEALQQQQTRLMKINHDLRHRVTVVEAQGKALIEQKVELEADLQTKEQEMGSLRA 245
Query: 186 ATPQAKERARGQAGRPGHQHGQEPEWATAGAGAPGNPEDPAEAAQQLGRPSEAGQCRFSR 245
+ +ER +G+ + G +EPE G + + E A + RP RF+
Sbjct: 246 ELGKLRERLQGEHSQNGE---EEPETEPVGEESISDAEKVAMDLKDPNRP------RFTL 296
Query: 246 EEFEQILQERNELKAKVFLLKEELAYFQ-RELLTDHRVP 283
+E +L ERNELK+KVFLL+EELAY++ E+ ++R+P
Sbjct: 297 QELRDVLHERNELKSKVFLLQEELAYYKSEEMEEENRIP 335
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 52.0 bits (123), Expect = 1e-06
Identities = 73/303 (24%), Positives = 120/303 (39%), Gaps = 37/303 (12%)
Query: 90 RLREENERLRRELRAGPQEERALLRQLKEVTDRQRDELRAHNRDLRQRGQETEALQEQLQ 149
R RE++ RE + ER R+ + +R+R+ R R+ ++ E ++ +
Sbjct: 383 RSREKSRDREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYE 442
Query: 150 RLLLVNAELRHKLAAMQTQLRAAQDRERERQQPGEAATPQAKERARGQAGRPGHQHGQEP 209
R L +LR K AA Q +L+ + RER++ + E + +ER R A
Sbjct: 443 RRKL-ERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLE 501
Query: 210 EWATAGAGAPGNPEDPAEAAQQLGRPSEAGQCRFSREEFEQILQERNELKAKVFLLKEEL 269
++ + +DP A Q R E E ER+ + K EEL
Sbjct: 502 DY-------DDDRDDPKYYR------GSALQKRLRDREKEMEADERDRKREK-----EEL 543
Query: 270 AYFQRELLTD-HRVPGLLLEAMKV-AVRKQRKKIKAKMLGTPEEAESSEDEAGPWILLSD 327
++ LL + H P L+ M+ A R+++ +IK + EE E E E
Sbjct: 544 EEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKE--------- 594
Query: 328 DKGDHPPPPESKIQSFFGLWYRGKAESSEDETSSPAPSKLGGEEEAQPQSPAPDPPCSAL 387
+K + P E + + L + SS APS A P +P + PC +
Sbjct: 595 EKREEPMEEEEEPEQKPCLKPTLRPISS-------APSVSSASGNATPNTPGDESPCGII 647
Query: 388 HEH 390
H
Sbjct: 648 IPH 650
Score = 44.3 bits (103), Expect = 2e-04
Identities = 52/216 (24%), Positives = 96/216 (44%), Gaps = 9/216 (4%)
Query: 86 QELRRLREENERLRRELRAGPQEERALLRQLKEVTDRQRDELRAHNRDLRQRGQETEALQ 145
+E+ + R+ +++L E G +E+ RQ E R+R+ R R+ R+R +E E +
Sbjct: 279 REISKFRDTHKKLEEE--KGKKEKE---RQEIEKERRERERERERERERRERERERERER 333
Query: 146 EQLQRLLLVNAELRHKLAAMQTQLRAAQDRERERQQPGEAATPQAKERARG-QAGRPGHQ 204
E+ + R + + +DRER+R + E ++ + K+R+R + R +
Sbjct: 334 EREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRER 393
Query: 205 HGQEPEWATAGAGAPGNPEDPAEAAQQLGRPSEAGQCRFSREEFEQILQERNELKAKVFL 264
+ E E ++ R E + R REE E+ ER +L+ K L
Sbjct: 394 EREREREREREREREREREREREREREREREREKDKKR-DREEDEEDAYERRKLERK--L 450
Query: 265 LKEELAYFQRELLTDHRVPGLLLEAMKVAVRKQRKK 300
++E AY +R + R E K A R++ ++
Sbjct: 451 REKEAAYQERLKNWEIRERKKTREYEKEAEREEERR 486
>gi|191252814 RIMS binding protein 3B [Homo sapiens]
Length = 1639
Score = 51.6 bits (122), Expect = 1e-06
Identities = 100/351 (28%), Positives = 139/351 (39%), Gaps = 65/351 (18%)
Query: 81 AQPAEQELRRLREENERLRREL---RAGPQEER----ALLRQLKEVTDRQRDEL--RAHN 131
+ PA L R E E+LR EL RAG + ER A RQL+E +R+R +L R +
Sbjct: 19 SSPAAAVLENQRRELEKLRAELEAERAGWRAERRRFAARERQLREEAERERRQLADRLRS 78
Query: 132 RDLRQRGQETEALQEQLQRLLLVNAELRHKLA---AMQTQLRAAQDRERERQQPGEAATP 188
+ QR +E LQE++QR AE+R L A Q QL+ RER +
Sbjct: 79 KWEAQRSRELRQLQEEMQRER--EAEIRQLLRWKEAEQRQLQQLLHRER------DGVVR 130
Query: 189 QAKERARGQAGRPGHQHGQEPEWATAG-AGAPGNPEDPAEAAQQLGRPSEA-GQCRFSRE 246
QA+E R A E G PG E AAQ R E Q R+ +
Sbjct: 131 QARELQRQLA----------EELVNRGHCSRPGASE--VSAAQCRCRLQEVLAQLRWQTD 178
Query: 247 EFE----QILQERNELKAKVFLLKEELAYFQ-RELLTDHRVPGLL--------------L 287
+ + LQ E++ ++FL K LA+F+ L+ P +
Sbjct: 179 GEQAARIRYLQAALEVERQLFL-KYILAHFRGHPALSGSPDPQAVHSLEEPLPQTSSGSC 237
Query: 288 EAMKVAVR-------KQRKKIKAKMLGTPEEAESSEDEAGPWILLSDDKGDHPPPPESKI 340
A K A + ++++ LG A SS + LLS +
Sbjct: 238 HAPKPACQLGSLDSLSAEVGVRSRSLGLVSSACSSSPDG----LLSTHASSLDCFAPACS 293
Query: 341 QSFFGLWYRGKAESSEDETSSPAPSKLGGEEEAQPQSPAPDPPCSALHEHL 391
+S KA SE+ SSP S G + P SP P PP + H L
Sbjct: 294 RSLDSTRSLPKASKSEERPSSPDTSTPGSRRLSPPPSPLPPPPPPSAHRKL 344
>gi|191252806 RIMS binding protein 3C [Homo sapiens]
Length = 1639
Score = 51.6 bits (122), Expect = 1e-06
Identities = 100/351 (28%), Positives = 139/351 (39%), Gaps = 65/351 (18%)
Query: 81 AQPAEQELRRLREENERLRREL---RAGPQEER----ALLRQLKEVTDRQRDEL--RAHN 131
+ PA L R E E+LR EL RAG + ER A RQL+E +R+R +L R +
Sbjct: 19 SSPAAAVLENQRRELEKLRAELEAERAGWRAERRRFAARERQLREEAERERRQLADRLRS 78
Query: 132 RDLRQRGQETEALQEQLQRLLLVNAELRHKLA---AMQTQLRAAQDRERERQQPGEAATP 188
+ QR +E LQE++QR AE+R L A Q QL+ RER +
Sbjct: 79 KWEAQRSRELRQLQEEMQRER--EAEIRQLLRWKEAEQRQLQQLLHRER------DGVVR 130
Query: 189 QAKERARGQAGRPGHQHGQEPEWATAG-AGAPGNPEDPAEAAQQLGRPSEA-GQCRFSRE 246
QA+E R A E G PG E AAQ R E Q R+ +
Sbjct: 131 QARELQRQLA----------EELVNRGHCSRPGASE--VSAAQCRCRLQEVLAQLRWQTD 178
Query: 247 EFE----QILQERNELKAKVFLLKEELAYFQ-RELLTDHRVPGLL--------------L 287
+ + LQ E++ ++FL K LA+F+ L+ P +
Sbjct: 179 GEQAARIRYLQAALEVERQLFL-KYILAHFRGHPALSGSPDPQAVHSLEEPLPQTSSGSC 237
Query: 288 EAMKVAVR-------KQRKKIKAKMLGTPEEAESSEDEAGPWILLSDDKGDHPPPPESKI 340
A K A + ++++ LG A SS + LLS +
Sbjct: 238 HAPKPACQLGSLDSLSAEVGVRSRSLGLVSSACSSSPDG----LLSTHASSLDCFAPACS 293
Query: 341 QSFFGLWYRGKAESSEDETSSPAPSKLGGEEEAQPQSPAPDPPCSALHEHL 391
+S KA SE+ SSP S G + P SP P PP + H L
Sbjct: 294 RSLDSTRSLPKASKSEERPSSPDTSTPGSRRLSPPPSPLPPPPPPSAHRKL 344
>gi|153792195 DKFZP434H0735 protein [Homo sapiens]
Length = 1639
Score = 51.6 bits (122), Expect = 1e-06
Identities = 100/351 (28%), Positives = 139/351 (39%), Gaps = 65/351 (18%)
Query: 81 AQPAEQELRRLREENERLRREL---RAGPQEER----ALLRQLKEVTDRQRDEL--RAHN 131
+ PA L R E E+LR EL RAG + ER A RQL+E +R+R +L R +
Sbjct: 19 SSPAAAVLENQRRELEKLRAELEAERAGWRAERRRFAARERQLREEAERERRQLADRLRS 78
Query: 132 RDLRQRGQETEALQEQLQRLLLVNAELRHKLA---AMQTQLRAAQDRERERQQPGEAATP 188
+ QR +E LQE++QR AE+R L A Q QL+ RER +
Sbjct: 79 KWEAQRSRELRQLQEEMQRER--EAEIRQLLRWKEAEQRQLQQLLHRER------DGVVR 130
Query: 189 QAKERARGQAGRPGHQHGQEPEWATAG-AGAPGNPEDPAEAAQQLGRPSEA-GQCRFSRE 246
QA+E R A E G PG E AAQ R E Q R+ +
Sbjct: 131 QARELQRQLA----------EELVNRGHCSRPGASE--VSAAQCRCRLQEVLAQLRWQTD 178
Query: 247 EFE----QILQERNELKAKVFLLKEELAYFQ-RELLTDHRVPGLL--------------L 287
+ + LQ E++ ++FL K LA+F+ L+ P +
Sbjct: 179 GEQAARIRYLQAALEVERQLFL-KYILAHFRGHPALSGSPDPQAVHSLEEPLPQTSSGSC 237
Query: 288 EAMKVAVR-------KQRKKIKAKMLGTPEEAESSEDEAGPWILLSDDKGDHPPPPESKI 340
A K A + ++++ LG A SS + LLS +
Sbjct: 238 HAPKPACQLGSLDSLSAEVGVRSRSLGLVSSACSSSPDG----LLSTHASSLDCFAPACS 293
Query: 341 QSFFGLWYRGKAESSEDETSSPAPSKLGGEEEAQPQSPAPDPPCSALHEHL 391
+S KA SE+ SSP S G + P SP P PP + H L
Sbjct: 294 RSLDSTRSLPKASKSEERPSSPDTSTPGSRRLSPPPSPLPPPPPPSAHRKL 344
>gi|194578923 sperm associated antigen 9 isoform 1 [Homo sapiens]
Length = 1321
Score = 50.4 bits (119), Expect = 3e-06
Identities = 45/164 (27%), Positives = 74/164 (45%), Gaps = 14/164 (8%)
Query: 17 EAAGSASA-AELVYHLAGALGTELQDLARRFGPEAAAGLVPLVVRALELLEQAAVGPAPD 75
E GS + +E V LAG++ E + L R+ E L+PLVV LE L D
Sbjct: 12 EPGGSGAVMSERVSGLAGSIYREFERLIGRYDEEVVKELMPLVVAVLENL---------D 62
Query: 76 SLQVSAQPAEQELRRLREENERLRRELRAGPQEERALLRQLKEVTDRQRDELRAHNRDLR 135
S+ Q + EL LR++NE+L + + E+AL + +E D +DL+
Sbjct: 63 SVFAQDQEHQVELELLRDDNEQLITQY----EREKALRKHAEEKFIEFEDSQEQEKKDLQ 118
Query: 136 QRGQETEALQEQLQRLLLVNAELRHKLAAMQTQLRAAQDRERER 179
R + E+ QL+ A+ +L + +L+ + +R
Sbjct: 119 TRVESLESQTRQLELKAKNYADQISRLEEREAELKKEYNALHQR 162
>gi|27436920 sperm associated antigen 9 isoform 3 [Homo sapiens]
Length = 1307
Score = 50.4 bits (119), Expect = 3e-06
Identities = 45/164 (27%), Positives = 74/164 (45%), Gaps = 14/164 (8%)
Query: 17 EAAGSASA-AELVYHLAGALGTELQDLARRFGPEAAAGLVPLVVRALELLEQAAVGPAPD 75
E GS + +E V LAG++ E + L R+ E L+PLVV LE L D
Sbjct: 12 EPGGSGAVMSERVSGLAGSIYREFERLIGRYDEEVVKELMPLVVAVLENL---------D 62
Query: 76 SLQVSAQPAEQELRRLREENERLRRELRAGPQEERALLRQLKEVTDRQRDELRAHNRDLR 135
S+ Q + EL LR++NE+L + + E+AL + +E D +DL+
Sbjct: 63 SVFAQDQEHQVELELLRDDNEQLITQY----EREKALRKHAEEKFIEFEDSQEQEKKDLQ 118
Query: 136 QRGQETEALQEQLQRLLLVNAELRHKLAAMQTQLRAAQDRERER 179
R + E+ QL+ A+ +L + +L+ + +R
Sbjct: 119 TRVESLESQTRQLELKAKNYADQISRLEEREAELKKEYNALHQR 162
>gi|94557295 mitogen-activated protein kinase 8 interacting protein
3 isoform 2 [Homo sapiens]
Length = 1330
Score = 50.4 bits (119), Expect = 3e-06
Identities = 47/157 (29%), Positives = 69/157 (43%), Gaps = 23/157 (14%)
Query: 25 AELVYHLAGALGTELQDLARRFGPEAAAGLVPLVVRALELLEQAAVGPAPDSLQVSAQPA 84
+E V LAG++ E + L + E L+PLVV LE L DS+ Q
Sbjct: 26 SERVSGLAGSIYREFERLIHCYDEEVVKELMPLVVNVLENL---------DSVLSENQEH 76
Query: 85 EQELRRLREENERLRRELRAGPQEERALLRQLKEVTDRQRDELRAHNRDLRQRGQETEAL 144
E EL LRE+NE+L + + E+AL RQ +E D L QE + L
Sbjct: 77 EVELELLREDNEQLLTQY----EREKALRRQAEEKFIEFEDALE----------QEKKEL 122
Query: 145 QEQLQRLLLVNAELRHKLAAMQTQLRAAQDRERERQQ 181
Q Q++ +L K Q+ ++RE E ++
Sbjct: 123 QIQVEHYEFQTRQLELKAKNYADQISRLEERESEMKK 159
>gi|94557297 mitogen-activated protein kinase 8 interacting protein
3 isoform 1 [Homo sapiens]
Length = 1336
Score = 50.4 bits (119), Expect = 3e-06
Identities = 47/157 (29%), Positives = 69/157 (43%), Gaps = 23/157 (14%)
Query: 25 AELVYHLAGALGTELQDLARRFGPEAAAGLVPLVVRALELLEQAAVGPAPDSLQVSAQPA 84
+E V LAG++ E + L + E L+PLVV LE L DS+ Q
Sbjct: 26 SERVSGLAGSIYREFERLIHCYDEEVVKELMPLVVNVLENL---------DSVLSENQEH 76
Query: 85 EQELRRLREENERLRRELRAGPQEERALLRQLKEVTDRQRDELRAHNRDLRQRGQETEAL 144
E EL LRE+NE+L + + E+AL RQ +E D L QE + L
Sbjct: 77 EVELELLREDNEQLLTQY----EREKALRRQAEEKFIEFEDALE----------QEKKEL 122
Query: 145 QEQLQRLLLVNAELRHKLAAMQTQLRAAQDRERERQQ 181
Q Q++ +L K Q+ ++RE E ++
Sbjct: 123 QIQVEHYEFQTRQLELKAKNYADQISRLEERESEMKK 159
>gi|91208420 bassoon protein [Homo sapiens]
Length = 3926
Score = 50.1 bits (118), Expect = 4e-06
Identities = 55/179 (30%), Positives = 79/179 (44%), Gaps = 15/179 (8%)
Query: 77 LQVSAQPAEQE-LRRLR--EENERLRRELRAGPQEERALLRQLKEVTDRQRDELRAHNRD 133
LQ+ + E E LR+LR EE ER R EL+ +EE+ L++ R+ EL+
Sbjct: 2373 LQLERERVELEKLRQLRLQEELERERVELQRHREEEQLLVQ-------RELQELQTIKHH 2425
Query: 134 LRQRGQETEALQEQLQRLLLVNAELR-HKLAAMQTQLRAAQDRERERQQPGEAATPQAKE 192
+ Q+ QE Q LQR L L+ ++ +Q QL+ + +++RQ+ A +A
Sbjct: 2426 VLQQQQEERQAQFALQREQLAQQRLQLEQIQQLQQQLQQQLEEQKQRQKAPFPAACEAPG 2485
Query: 193 RARGQAGRPGHQHGQE-PEWATAGAGAPGNPE---DPAEAAQQLGRPSEAGQCRFSREE 247
R A Q+GQ P A A PE P E G PS A EE
Sbjct: 2486 RGPPLAAAELAQNGQYWPPLTHAAFIAMAGPEGLGQPREPVLHRGLPSSASDMSLQTEE 2544
Score = 33.1 bits (74), Expect = 0.46
Identities = 47/195 (24%), Positives = 71/195 (36%), Gaps = 39/195 (20%)
Query: 67 QAAVGPAPDSLQVSAQPAEQELRRLREENERLRRELRAGPQEERALLRQLKEVTDRQRDE 126
QA GPA +LQ A+P Q + R+ GPQ+ ++ + RQ
Sbjct: 3727 QAHSGPA--ALQSKAEPQAQP--------QLQGRQAAPGPQQSQS-------PSSRQIPS 3769
Query: 127 LRAHNRDLRQRGQETEALQEQLQRLLLVNAELRHKLAAMQTQLRAAQDRERERQQPGEAA 186
A + Q+ Q+ LQ Q L + + + + A+Q + + P A
Sbjct: 3770 GAASRQPQTQQQQQGLGLQPPQQALTQARLQQQSQPTTRGSAPAASQPAGKPQPGPSTAT 3829
Query: 187 TPQ----------------AKERARGQAGRPGHQHGQEPEWATAGAGAPGNPEDPAEAAQ 230
PQ AK +G+A + G P AGA G P PA
Sbjct: 3830 GPQPAGPPRAEQTNGSKGTAKAPQQGRAPQAQPAPGPGPAGVKAGARPGGTPGAPA---- 3885
Query: 231 QLGRPSEAGQCRFSR 245
G+P G+ FS+
Sbjct: 3886 --GQPGADGESVFSK 3898
Score = 32.7 bits (73), Expect = 0.60
Identities = 60/249 (24%), Positives = 96/249 (38%), Gaps = 45/249 (18%)
Query: 15 SREAAGSASAAELVYHLAGALGTELQ-----DLARRFG-------PEAA----AGLVPLV 58
S A SA +Y G LG+++ L R+ PE A AG
Sbjct: 2857 SPTAEESAKERFSLYQHQGGLGSQVSALPPNSLVRKVKRTLPSPPPEEAHLPLAGQASPQ 2916
Query: 59 VRALELLEQAAVGPA--PDSLQVSAQPAEQELRRLREENERLRRELRAGPQEERALLRQL 116
+ A LL++ GP P + + +++LR + E+ +LR++ +EE+ + +L
Sbjct: 2917 LYAASLLQRGLTGPTTVPATKASLLRELDRDLRLVEHESTKLRKKQAELDEEEKEIDAKL 2976
Query: 117 K--EVTDRQRDELRAHNR------DLRQRGQETEALQE-QLQRLLLVNAELRHKLAAMQT 167
K E+ QR E A +R LR G+ + L + +L +L +L T
Sbjct: 2977 KYLELGITQRKESLAKDRGGRDYPPLRGLGEHRDYLSDSELNQL---------RLQGCTT 3027
Query: 168 QLRAAQDRERERQQPGEAATPQAKERARGQAGRPGHQHGQEPEWATAGAGAPGNPEDPAE 227
D P + P A ++ R Q P + +AG+G P PA
Sbjct: 3028 PAGQFVDFPATAAAPATPSGPTAFQQPRFQPPAPQY---------SAGSGGPTQNGFPAH 3078
Query: 228 AAQQLGRPS 236
A PS
Sbjct: 3079 QAPTYPGPS 3087
Score = 29.6 bits (65), Expect = 5.1
Identities = 30/119 (25%), Positives = 45/119 (37%), Gaps = 11/119 (9%)
Query: 121 DRQRDELRAHNRDLRQRGQETEALQEQLQRLLLVNAELRHKLAAMQTQLRAAQDRERERQ 180
D R E R H++ A+ ++ Q +AE A A+ ++ RQ
Sbjct: 3673 DLGRHEARPHSQP-----SSAPAMPKKGQPGYPSSAEYSQPSRASSAYHHASDSKKGSRQ 3727
Query: 181 -QPGEAAT-----PQAKERARGQAGRPGHQHGQEPEWATAGAGAPGNPEDPAEAAQQLG 233
G AA PQA+ + +G+ PG Q Q P +GA + Q LG
Sbjct: 3728 AHSGPAALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQQQGLG 3786
>gi|111955084 5-azacytidine induced 1 isoform a [Homo sapiens]
Length = 1080
Score = 50.1 bits (118), Expect = 4e-06
Identities = 66/243 (27%), Positives = 106/243 (43%), Gaps = 32/243 (13%)
Query: 85 EQELRRLRE--ENERLRRELRAGP------QEERALLRQLKEVTDRQRDELRAHNRDLRQ 136
+QE+RRL+ E E L+ + RA +E R L + KE +Q E RA R +
Sbjct: 720 KQEVRRLKSLHEAELLQSDERASQRCLRQAEELREQLEREKEALGQQERE-RARQRFQQH 778
Query: 137 RGQETEALQEQLQRLLLVNAELRHKLAAMQTQLRAAQDRERERQQPGEAATPQAKERARG 196
QE ALQ+Q QRL AE R +L + RA + R++ + +A +A RA
Sbjct: 779 LEQEQWALQQQRQRLYSEVAEERERLGQQAARQRAELEELRQQLEESSSALTRAL-RAEF 837
Query: 197 QAGRPGHQHGQEPEWATAGAGAPGNPEDPAEAAQQLGRPSEAGQCRFSREEFEQILQERN 256
+ GR + + E T QQL +A + +R+E +L
Sbjct: 838 EKGREEQERRHQMELNT--------------LKQQLELERQAWEAGRTRKEEAWLLNREQ 883
Query: 257 ELKAKVFLLKEELAYFQRELLTDHRVP---GLLLEAMKVAVRKQRKKIKAKMLGTPEEAE 313
EL+ ++ +++ + EL+ HR+ L E + A + K+++ K E E
Sbjct: 884 ELREEIRKGRDK----EIELVI-HRLEADMALAKEESEKAAESRIKRLRDKYEAELSELE 938
Query: 314 SSE 316
SE
Sbjct: 939 QSE 941
Score = 33.9 bits (76), Expect = 0.27
Identities = 34/117 (29%), Positives = 52/117 (44%), Gaps = 7/117 (5%)
Query: 80 SAQPAEQELRRLREENERLRRELRAGPQEERALLRQLKEVTDRQRDELRAHNRDLRQRGQ 139
S + AE ++RLR++ E EL Q ER L + E+ Q E N L+ +
Sbjct: 915 SEKAAESRIKRLRDKYEAELSELE---QSERKLQERCSELKG-QLGEAEGENLRLQGLVR 970
Query: 140 ETEALQEQLQRLLLVNAELRHKLAAM---QTQLRAAQDRERERQQPGEAATPQAKER 193
+ E E Q + + R LA + + + R A E RQ E AT QA+++
Sbjct: 971 QKERALEDAQAVNEQLSSERSNLAQVIRQEFEDRLAASEEETRQAKAELATLQARQQ 1027
>gi|115648142 centrosomal protein 164kDa [Homo sapiens]
Length = 1460
Score = 49.7 bits (117), Expect = 5e-06
Identities = 87/352 (24%), Positives = 135/352 (38%), Gaps = 72/352 (20%)
Query: 2 EPRRAAPGVPGWGSREAAGSASAAELVYHL------------AGALGTELQDLARRFGP- 48
EP + G P W E G SAA L L A G E A GP
Sbjct: 493 EPPQGPEGQPEWKEAEELGEDSAASLSLQLSLQREQAPSPPAACEKGKEQHSQAEELGPG 552
Query: 49 -------EAAAGLVPLVVRALELLEQAAVGPAPDSLQVSAQPAEQELRRLREENERLRRE 101
E + P + E+ V P + + + E+ + ++ E+++R
Sbjct: 553 QEEAEDPEEKVAVSPTPPVSPEVRSTEPVAPPEQLSEAALKAMEEAVAQVLEQDQR---H 609
Query: 102 LRAGPQEERALLRQLKEVTDRQRDELRAHNR------DLRQRGQ------ETEALQEQLQ 149
L QE+ LR+ K + + + LR H + LR+R Q E +E+ Q
Sbjct: 610 LLESKQEKMQQLRE-KLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEEEEARMREEESQ 668
Query: 150 RLLLVNAELRHKLAAMQTQLRAAQD-------RERERQQPGEAATPQAKERARGQAGRPG 202
RL + A+++ A + Q+RA Q+ E E QQ E A+ + K R + +
Sbjct: 669 RLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQKNRQMLEQLKEE 728
Query: 203 HQHGQEPEWATAGAGAPGNPEDPAEAAQQLGRPSEAGQCRFSREEFEQILQERNELKAKV 262
+ ++ E A A +A QQL EQ+ ER E A
Sbjct: 729 IEASEKSEQAALNAA-------KEKALQQLR---------------EQLEGERKE--AVA 764
Query: 263 FLLKEELAYFQR---ELLTDHR-VPGLLLEAMKVAVRKQRKKIKAKMLGTPE 310
L KE A +R L HR V L + ++ A +K+ +++ K LG E
Sbjct: 765 TLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQ-KCLGQVE 815
Score = 32.0 bits (71), Expect = 1.0
Identities = 72/326 (22%), Positives = 127/326 (38%), Gaps = 47/326 (14%)
Query: 85 EQELRRLREENERL----RRELRAGPQEERALLRQLKEVTDRQRDELRAHNRDLRQRGQE 140
E+ L +++EE++++ R + A +++RA L L +T RAH R+L QE
Sbjct: 848 ERRLDKMKEEHQQVMAKAREQYEAEERKQRAEL--LGHLTGELERLQRAHERELETVRQE 905
Query: 141 TEALQEQLQRL----------LLVNAELRHKLAAMQTQLRAAQDRERERQQPGEAATPQA 190
E L+R L ++ E R K + L Q+ E R++ + Q
Sbjct: 906 QHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQE-ETARREKQQLLDVQR 964
Query: 191 KERARGQAGRPGHQHGQEPEWATAGAGAPGNPEDPAEAAQQLGRPSEAGQCRFSREEFE- 249
+ + + HQ +E A ++ QQL + Q R + E +
Sbjct: 965 QVALKSEEATATHQQLEE---------AQKEHTHLLQSNQQLREILDELQARKLKLESQV 1015
Query: 250 QILQERNELKAKVFLLKEELAYFQRELLTD----------HRVPGLLLEAMKVAV-RKQR 298
+LQ +++ K F E A ++ LL + H P L +E ++ ++ Q
Sbjct: 1016 DLLQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFEPDLHIEDLRKSLGTNQT 1075
Query: 299 KKIKAKMLGTPEEAE-SSEDEAGPWILLSDDKGDHPPPPESKIQSFFGLWYRGKAESSED 357
K++ + + + E+ S W LLS + E +Q + R
Sbjct: 1076 KEVSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLVQQTRSMRRR-------- 1127
Query: 358 ETSSPAPSKLGGEEEAQPQSPAPDPP 383
+T+ A + E A Q A DPP
Sbjct: 1128 QTALKAAQQHWRHELASAQEVAKDPP 1153
>gi|239745099 PREDICTED: similar to Golgin subfamily A member 8-like
protein 1 isoform 1 [Homo sapiens]
Length = 632
Score = 49.3 bits (116), Expect = 6e-06
Identities = 55/223 (24%), Positives = 93/223 (41%), Gaps = 31/223 (13%)
Query: 60 RALELLEQAAVGPAPDSLQVSAQPAEQELRRLREENERLRRELRAGPQEERALLRQLKEV 119
R+L L+ P P + A P+E EL+ LR+E ER+ EL+A + +++ +
Sbjct: 282 RSLSKLKNQMAEPLPP--EPPAVPSEVELQHLRKELERVAGELQAQVKNN----QRISLL 335
Query: 120 TDRQRDELRAHNRDLRQRGQETEALQEQLQRLLLVNAELRHKLAAMQTQLRAAQDRERER 179
RQ + +R LR++ + + + LQ+L + ++ L+ Q + +
Sbjct: 336 NQRQEERIREQEERLRKQEERIQEQHKSLQQLAKPQSVFEEPNNENKSTLQLEQQVKELQ 395
Query: 180 QQPGE---AATPQAKERARGQ---AGRPGHQHGQE---PEWATAGAGAPGNPEDPAEAAQ 230
++ GE A Q ++ Q PG HG E E A P PEDP
Sbjct: 396 EKLGEEHLEAASQQNQQLTAQLSLMALPGEGHGGEHLDSEGEEAPQPMPSVPEDP----- 450
Query: 231 QLGRPSEAGQCRFSREEFEQILQERNELKAKVFLLKEELAYFQ 273
+ R + F L+E+ +L V K+EL + Q
Sbjct: 451 ---------ESREAMSSFMDHLEEKADLSELV--KKQELRFIQ 482
Score = 34.3 bits (77), Expect = 0.21
Identities = 40/166 (24%), Positives = 71/166 (42%), Gaps = 29/166 (17%)
Query: 110 RALLRQLKEVTDRQRDELRAHNRDLRQRGQETEALQEQLQRLLLVNAELRHKLAAMQTQL 169
++L +Q K+V + +E +A+N+ + + L+ QLQ L + EL L M+ L
Sbjct: 101 KSLKQQKKQVEHQLEEEKKANNKKQKAK----RVLEVQLQTLNIQKEELNTDLYHMKRSL 156
Query: 170 RAAQDRERERQQPGEAATPQAKERARGQAGRPGHQHGQEPEWATAGAGAPGNPEDPAEAA 229
R +E+++ A R H ++ E + + + + A
Sbjct: 157 R------------------YFEEKSKDLAVRLQHSLQRKGELESVLSDVMATQK---KKA 195
Query: 230 QQLGRPSEAGQCRFSREEFEQILQERNELKAKVFLLKEELAYFQRE 275
QL PS+AG + + EQ ++E LK ++ LKE Q E
Sbjct: 196 NQLSSPSKAG----TEWKLEQSMREEALLKVQLTQLKESFQQVQLE 237
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 49.3 bits (116), Expect = 6e-06
Identities = 49/192 (25%), Positives = 81/192 (42%), Gaps = 5/192 (2%)
Query: 85 EQELRRLREENERLRRELRAGPQEERALLRQLKEVTDRQRDELRAHNRDLRQRGQETEAL 144
EQ+LRR +EE RRE R QEE L+Q + R E L +R +E
Sbjct: 504 EQQLRREQEE----RREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLE 559
Query: 145 QEQL-QRLLLVNAELRHKLAAMQTQLRAAQDRERERQQPGEAATPQAKERARGQAGRPGH 203
QE+ QRL E R +L + + R + + + ++ + + ER + R
Sbjct: 560 QERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQR 619
Query: 204 QHGQEPEWATAGAGAPGNPEDPAEAAQQLGRPSEAGQCRFSREEFEQILQERNELKAKVF 263
+EPE ++ Q E + R REE E+ L++R + + +
Sbjct: 620 LKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEE 679
Query: 264 LLKEELAYFQRE 275
++ELA ++E
Sbjct: 680 RREQELAEEEQE 691
Score = 47.8 bits (112), Expect = 2e-05
Identities = 61/250 (24%), Positives = 108/250 (43%), Gaps = 25/250 (10%)
Query: 78 QVSAQPAEQELRRLREENERLRRELRAGPQEERALLR--QLKEVTDRQRDELRAHNRDLR 135
Q Q E++LR+L E + LRRE + Q+++ L R QL+ + +R E + R+ +
Sbjct: 268 QRELQEEEEQLRKL--ERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQ 325
Query: 136 QRGQETEALQEQLQRLLLVNAELRHKLAAMQTQLRAAQDRERERQQPGEAATPQAKER-- 193
+R ++ E +EQ R R + + QLR Q+ ER QQ + +E+
Sbjct: 326 ERREQQEERREQQLR--------REQEERREQQLRREQEEERREQQLRREQEEERREQQL 377
Query: 194 ARGQAGRPGHQHGQEPEWATAGAGAPGNPEDPAEAAQQLGRPSE-AGQCRFSREEFEQIL 252
R Q R Q +E + E QQL R + + + RE+ E+
Sbjct: 378 RREQQLRREQQLRREQQLRRE---QQLRREQQLRREQQLRREQQLRREQQLRREQEEERH 434
Query: 253 QERNELKAKVFLLKEELA----YFQRELLTDHRVPGLLLEAMKVAVRKQRKKIKAKMLGT 308
++++E + + LK E + +RE T+ + +K R Q ++ + + L
Sbjct: 435 EQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLK---RDQEEERRERWLKL 491
Query: 309 PEEAESSEDE 318
EE + E
Sbjct: 492 EEEERREQQE 501
Score = 47.8 bits (112), Expect = 2e-05
Identities = 67/245 (27%), Positives = 103/245 (42%), Gaps = 29/245 (11%)
Query: 85 EQELRRLREENERLRRELRAGPQEERALLRQLKEVTDRQRDELRAHNRDLRQRGQETEAL 144
E+ +R R+E ER RE QEE LLR+ +E R+R EL R+ + QE E L
Sbjct: 1096 EEPEKRRRQERERQCREEEELQQEEEQLLREERE--KRRRQELERQYREEEEVQQEEEQL 1153
Query: 145 ---------QEQLQRLLLVNAELRHKLAAMQTQLRAAQDRERERQ--QPGEAATPQAKER 193
+++L+R EL+ + + + + + +ERERQ + E + K+R
Sbjct: 1154 LREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQR 1213
Query: 194 ARGQAGRPGHQHGQEPEWATAGAGAPGNPEDPAEAAQQLGRPSEAGQC--RFSREEFEQI 251
R + R + EPE A N + R E Q R S+++ + +
Sbjct: 1214 YRDEDQRSDLKWQWEPEKENA---VRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHL 1270
Query: 252 LQERNELKAKVFLLKEELAYFQRELLTDHRVP---GLLLEAMKVAVRKQRKKIKAKMLGT 308
L E+ E + +E + QR D P L E K A R+ RK + K L
Sbjct: 1271 LGEQQERDRE----QERRRWQQR----DRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLR 1322
Query: 309 PEEAE 313
E E
Sbjct: 1323 EEREE 1327
Score = 47.0 bits (110), Expect = 3e-05
Identities = 64/258 (24%), Positives = 115/258 (44%), Gaps = 31/258 (12%)
Query: 86 QELRRLREENERLRRELRAGPQEERAL-LRQLKEVTDRQRDELRAHNRDLRQRGQETEAL 144
+E+ RL +E R +R R P+EER L + +E +R++ +LR ++ R++ + E
Sbjct: 605 EEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEE 664
Query: 145 QEQL-QRLLLVNAELRHKLAAMQTQLRAAQDRERER------QQPGEAATPQAK--ERAR 195
+E+L QRL + E R + + + A++R + R Q EA Q+K R R
Sbjct: 665 EERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPR 724
Query: 196 GQAGRPGHQHGQEPEWATAGAGAPGNPEDPAEAAQ-------------QLGRPSEAGQCR 242
Q G+ Q QE + + E+ A Q Q SE G+ R
Sbjct: 725 KQEGQRRRQE-QEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQR 783
Query: 243 FS-----REEFEQIL--QERNELKAKVFLLKEELAYFQRELLTDHRVPGLLLEAMKVAVR 295
S RE+ E+ L +ER + + + +EE +R+ + L E ++ R
Sbjct: 784 LSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRR 843
Query: 296 KQRKKIKAKMLGTPEEAE 313
++ ++++ + G E+ E
Sbjct: 844 ERAQQLQEEEDGLQEDQE 861
Score = 45.8 bits (107), Expect = 7e-05
Identities = 54/237 (22%), Positives = 95/237 (40%), Gaps = 33/237 (13%)
Query: 85 EQELRRLREENERLRRELRAGPQEERALLRQLKEVTDRQRDELRAHNRDLRQRGQETEAL 144
E+ +R R+E E+ RE QEE LLR+ +E RQ E + +D Q+ +E
Sbjct: 976 EEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLR 1035
Query: 145 QEQLQRLLLVNAELRHKLAAMQTQLRAAQDRERERQQPGEAATPQAKERARGQAGRPGHQ 204
+E+ +R L +ERERQ E Q +E+ G+ +
Sbjct: 1036 EEREKRRL----------------------QERERQYREEEELQQEEEQLLGEERETRRR 1073
Query: 205 HGQEPEWATAGAGAPGNPEDPAEAAQQLGRPSEAGQCRFSRE---EFEQILQERNELKAK 261
E ++ + E ++ R QCR E E EQ+L+E E +
Sbjct: 1074 QELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRR- 1132
Query: 262 VFLLKEELAYFQRELLTDHRVPGLLLEAMKVAVRKQRKKIKAKMLGTPEEAESSEDE 318
++EL +R+ + V + ++ K+R++ + EE + E++
Sbjct: 1133 ----RQEL---ERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQ 1182
Score = 45.1 bits (105), Expect = 1e-04
Identities = 67/249 (26%), Positives = 106/249 (42%), Gaps = 27/249 (10%)
Query: 86 QELRRLREENE----RLRREL---------RAGPQEERALLRQLKEVTDRQRD-ELRAHN 131
QELRR R+E E RLRRE R QEER ++ +E + +R+ +LR
Sbjct: 284 QELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQ 343
Query: 132 RDLRQ----RGQETEALQEQLQRLLLVNAELRHKLAAMQTQLRAAQDRERERQQPGEAAT 187
+ R+ R QE E ++QL+R E R + + QLR Q RE+Q E
Sbjct: 344 EERREQQLRREQEEERREQQLRR--EQEEERREQQLRREQQLRREQQLRREQQLRREQQL 401
Query: 188 PQAKERARGQAGRPGHQHGQEPEWATAGAGAPGNPEDPAEAAQQ-LGRPSEAGQCRFSRE 246
+ ++ R Q R Q +E + + E +Q L R E + RE
Sbjct: 402 RREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKRE 461
Query: 247 EFEQILQERNELKAKVFLLKEELAYFQRE--LLTDHRVPGLLLEAMKVAVRKQRKKIKAK 304
E ER+E + + LK + +RE L + E + +R+++++ + +
Sbjct: 462 E----ETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQ 517
Query: 305 MLGTPEEAE 313
L EE E
Sbjct: 518 RLKRQEEEE 526
Score = 44.3 bits (103), Expect = 2e-04
Identities = 62/261 (23%), Positives = 110/261 (42%), Gaps = 41/261 (15%)
Query: 85 EQELRRLREENERLRRELRAGPQEERALLRQLKEVTDRQRDELRAHNRDLRQRGQETE-- 142
E+EL+ L EE + RRE QEE L++ D++R + RD + R Q E
Sbjct: 828 EKELQFLEEEEQLQRRERAQQLQEEEDGLQE-----DQERRRSQEQRRDQKWRWQLEEER 882
Query: 143 -----------ALQEQLQRLLLVNAELRHKLAAMQTQLRAAQDRER------ERQQPGEA 185
ALQEQL++ + E +L + + R Q++ER + QQ E
Sbjct: 883 KRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQ 942
Query: 186 ATPQAKERARGQAGRPGHQHG---QEPEWATAGAGAPGNPEDPAEAAQQLGRPSEAGQCR 242
+ +E+ R Q ++ Q+ E G E+P + +Q +
Sbjct: 943 LLREEREKRRRQERERQYRKDKKLQQKEEQLLG-------EEPEKRRRQEREKKYREEEE 995
Query: 243 FSREEFEQILQERNELK-----AKVFLLKEELAYFQRELLTDHRVPGLLLE-AMKVAVRK 296
+EE EQ+L+E E + + + K+EL + +LL + R L E + +
Sbjct: 996 LQQEE-EQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEE 1054
Query: 297 QRKKIKAKMLGTPEEAESSED 317
+ ++ + ++LG E ++
Sbjct: 1055 ELQQEEEQLLGEERETRRRQE 1075
Score = 43.5 bits (101), Expect = 3e-04
Identities = 62/269 (23%), Positives = 112/269 (41%), Gaps = 28/269 (10%)
Query: 60 RALELLEQAAVGPAPDSLQVSAQPAEQEL----RRLREENERLRREL--RAGPQEERALL 113
RA E Q+ G + Q +EL R+ REE ++ RRE R +EE
Sbjct: 187 RAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEW 246
Query: 114 RQLKEVTDRQRDELR----AHNRDLRQRGQETEALQEQLQRLLLVNAELRHKLAAMQTQL 169
R+ + V ++ ++L+ R+L++ ++ L+ Q R E + + + QL
Sbjct: 247 RKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQL 306
Query: 170 RAAQDRERERQQPGEAATPQAKERARGQAGRPGHQHGQEPEWATAGAGAPGNPEDPAEAA 229
R Q+ ER QQ + +ER Q R Q +E E E+ E
Sbjct: 307 RRKQEEERREQQEERR---EQQERREQQEERREQQLRREQEERREQQLRREQEEERRE-- 361
Query: 230 QQLGRPSEAGQCRFSREEFEQILQERNELKAKVFLLKEELAYFQRELLTDHRVPGLLLEA 289
QQL R E E EQ L+ +L+ + L +E+ +++L + ++
Sbjct: 362 QQLRREQE-------EERREQQLRREQQLRREQQLRREQQLRREQQLRREQQL------R 408
Query: 290 MKVAVRKQRKKIKAKMLGTPEEAESSEDE 318
+ +R++++ + + L +E E E +
Sbjct: 409 REQQLRREQQLRREQQLRREQEEERHEQK 437
Score = 43.5 bits (101), Expect = 3e-04
Identities = 57/256 (22%), Positives = 108/256 (42%), Gaps = 36/256 (14%)
Query: 85 EQELRRLREENERLRRELRAGPQEERALLRQLKEVTDRQRDELRAHNRDLRQ----RGQE 140
EQ+LRR E+ ER ++LR +EER + +E + +R++ + LR+ R ++
Sbjct: 336 EQQLRR--EQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQ 393
Query: 141 TEALQEQLQRLLLVNAE---LRHKLAAMQTQLRAAQDRERERQQ---------------- 181
++QL+R + E R + + QLR Q+ ER Q+
Sbjct: 394 QLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEE 453
Query: 182 -----PGEAATPQAKERARGQAGRPGHQHGQEPEWATAGAGAPGNPEDPAEAAQQLGR-P 235
E T + ++ R Q + + + W ++ E QQL R
Sbjct: 454 RRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERRE--QQLRREQ 511
Query: 236 SEAGQCRFSREEFEQILQERNELKAKVFLLKEELAYFQRELLTDHRVPGLLLEAMKVAVR 295
E + R R+E E+ LQ+R + + L+ E + +LL L E + ++
Sbjct: 512 EERREQRLKRQEEEERLQQRLRSEQQ---LRREQEERREQLLKREEEKRLEQERREQRLK 568
Query: 296 KQRKKIKAKMLGTPEE 311
+++++ + ++L EE
Sbjct: 569 REQEERRDQLLKREEE 584
Score = 42.4 bits (98), Expect = 8e-04
Identities = 51/215 (23%), Positives = 94/215 (43%), Gaps = 29/215 (13%)
Query: 82 QPAEQELR-RLREENERLRRELRAGPQEERALLRQLKEVTDRQRDELRAHNRDLRQRGQ- 139
Q +Q+ R +L EE +R R L A P + L R+ +++ + +EL+ R+ R+R +
Sbjct: 868 QRRDQKWRWQLEEERKRRRHTLYAKPALQEQL-RKEQQLLQEEEEELQREEREKRRRQEQ 926
Query: 140 -----ETEALQEQLQRLLLVNAELRHKLAAMQTQLRAAQDRERERQQPGEAATPQAKERA 194
E E LQ++ ++LL E R + +ERERQ + Q +E+
Sbjct: 927 ERQYREEEQLQQEEEQLLREEREKRRR-------------QERERQYRKDKKLQQKEEQL 973
Query: 195 RGQAGRPGHQHGQEPEWATAGAGAPGNPEDPAEAAQQLGRPSEAGQCRFS---REEFEQI 251
G+ + +E ++ + E ++ R Q R ++E EQ+
Sbjct: 974 LGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQL 1033
Query: 252 LQERNEL-----KAKVFLLKEELAYFQRELLTDHR 281
L+E E + + + +EEL + +LL + R
Sbjct: 1034 LREEREKRRLQERERQYREEEELQQEEEQLLGEER 1068
Score = 41.6 bits (96), Expect = 0.001
Identities = 48/197 (24%), Positives = 85/197 (43%), Gaps = 30/197 (15%)
Query: 85 EQELRR----LREENERLRRELRAGPQEERALLRQLKEVTD--RQRDELRAHNRDLRQRG 138
EQ+LRR RE+ E + + E+ L R+ +E D ++ +E H ++ R++
Sbjct: 416 EQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQ 475
Query: 139 QETEALQEQLQR-LLLVNAELRHKLAAMQTQLRAAQDRERERQQPGEAATPQAKERARGQ 197
+ + +E+ +R L L E R + + QLR Q+ RE++ + + ++R R +
Sbjct: 476 LKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSE 535
Query: 198 AGRPGHQHGQEPEWATAGAGAPGNPEDPAEAAQQLGRPSEAGQCRFSREEFEQILQERNE 257
Q +E E E +QL + E + R +E EQ L+ E
Sbjct: 536 -----QQLRREQE----------------ERREQLLKREE--EKRLEQERREQRLKREQE 572
Query: 258 LKAKVFLLKEELAYFQR 274
+ L +EE QR
Sbjct: 573 ERRDQLLKREEERRQQR 589
Score = 41.6 bits (96), Expect = 0.001
Identities = 46/182 (25%), Positives = 82/182 (45%), Gaps = 25/182 (13%)
Query: 81 AQPAEQELRRLREENERLRRELRAGPQEERALLRQLKEVTDRQRDELRAHNRDLRQRGQE 140
+Q +Q LR REE R + R +EE+ L + ++ RQ + + +LR + Q
Sbjct: 1314 SQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQG 1373
Query: 141 TEALQEQLQRLLLVNAELR-----HKLAAMQTQLRAAQDRERERQQPGEAATPQAKERAR 195
+ L+E+ QRL E + +L + + + QDR+R+ ++ + + Q ++R
Sbjct: 1374 RKFLEEE-QRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKF 1432
Query: 196 GQAGRPGHQHGQEPEWATAGAGAPGNPEDPAEAAQQLGRPSEAGQCRFSREEFEQILQER 255
+ + + +E ++ E QQL + R REE EQ+LQER
Sbjct: 1433 REEEQQVRRQERERKF--------------LEEEQQLRQERH----RKFREE-EQLLQER 1473
Query: 256 NE 257
E
Sbjct: 1474 EE 1475
Score = 40.8 bits (94), Expect = 0.002
Identities = 57/237 (24%), Positives = 95/237 (40%), Gaps = 20/237 (8%)
Query: 84 AEQELRRLREENER--LRRELRAGPQEERALLRQLKEVTDRQRDELRAHNRDLRQRGQET 141
+EQ+LRR +EE L+RE ++ER R LK + +RD+L + RQ+ +
Sbjct: 534 SEQQLRREQEERREQLLKREEEKRLEQERREQR-LKREQEERRDQLLKREEERRQQRLKR 592
Query: 142 EALQEQLQRLLLVNAELRHKLAAMQTQLRAAQDRERERQQPGEAATPQAKERARGQAGRP 201
E + QRL E + + +L+ + E RQQ + +E R Q R
Sbjct: 593 EQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQ---LLKSEEQEERRQQQLRR 649
Query: 202 GHQHGQEPEWATAGAGAPGNPEDPAEAAQQLGRPSEAGQCRFSREEFEQILQERNELKAK 261
Q +E E+ Q+L R E + E EQ Q R +K++
Sbjct: 650 EQQERREQRLK--------REEEEERLEQRLKREHEEERREQELAEEEQ-EQARERIKSR 700
Query: 262 VFLLKEELAYFQRELLTDHRVPGLLLEAMKVAVRKQRKKIKAKMLGTPEEAESSEDE 318
+ +Q E D R + K +++R++ + K E + E+E
Sbjct: 701 I-----PKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEE 752
Score = 40.4 bits (93), Expect = 0.003
Identities = 46/151 (30%), Positives = 64/151 (42%), Gaps = 27/151 (17%)
Query: 78 QVSAQPAEQELRRLREENE--RLRRELRAGPQEERALLRQLKEVTDR------------- 122
+V ++P +QE +R R+E E R RRE QEE RQ +E R
Sbjct: 718 KVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKS 777
Query: 123 ----QRDELRAHNRDLRQRGQETEALQEQLQRLLLVNAELRHKLAAMQTQLRAAQDRERE 178
QR R R+ R+R E Q++ QR L E + + R ++RE+E
Sbjct: 778 ERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEE-------KEQRRRQRREREKE 830
Query: 179 RQQPGEAATPQAKERARG-QAGRPGHQHGQE 208
Q E Q +ERA+ Q G Q QE
Sbjct: 831 LQFLEEEEQLQRRERAQQLQEEEDGLQEDQE 861
Score = 39.7 bits (91), Expect = 0.005
Identities = 53/221 (23%), Positives = 89/221 (40%), Gaps = 18/221 (8%)
Query: 72 PAPDSLQVSAQPAEQELRRL----REENERLRRELRAGPQEERALLRQLKEVTDRQRDEL 127
P + Q + EQE RR RE+ ER + L+ +EER L ++LK + +R E
Sbjct: 625 PEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEER-LEQRLKREHEEERREQ 683
Query: 128 RAHNRDLRQRGQETEALQEQLQRLLLVNAELR----HKLAAMQTQLRAAQDRERERQQPG 183
+ Q + ++ + Q L A+ R + Q R Q++E +R++
Sbjct: 684 ELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRE 743
Query: 184 EAATPQAKERARGQAGRPGHQHGQEPEWATAGAGAPG----NPEDPAEAAQQLGRPSEAG 239
Q +ERA Q + +W G + P ++ +E
Sbjct: 744 SELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEER 803
Query: 240 QCRFSR-----EEFEQILQERNELKAKVFLLKEELAYFQRE 275
Q R R EE EQ ++R E + ++ L+EE +RE
Sbjct: 804 QQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRE 844
Score = 39.3 bits (90), Expect = 0.006
Identities = 63/250 (25%), Positives = 103/250 (41%), Gaps = 27/250 (10%)
Query: 82 QPAEQELRRLREENERLRRELRAGPQEERALLRQLKEVTDRQR-DELRAHNRDLRQRGQE 140
Q E+ +R R++ + REL G EE++ ++ E DRQR DE R Q +E
Sbjct: 128 QLEEEPGQRRRQKRQEQERELAEG--EEQSEKQERLEQRDRQRRDEELWRQRQEWQEREE 185
Query: 141 TEALQEQLQRLLLVNAE--------LRHKLAAMQTQLRAAQDRERERQQPGEAATPQAKE 192
A +EQLQ E R +L ++ + R + ++R +Q + KE
Sbjct: 186 RRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKE 245
Query: 193 -RARGQAGRPGHQHGQEPEWATAGAGAPGNPEDPAEAAQQLGRPSEAGQCRFSREEFE-- 249
R R R + QE E P + E +QL R E + R R+E E
Sbjct: 246 WRKRETVLRKEEEKLQEEE--------PQRQRELQEEEEQL-RKLERQELRRERQEEEQQ 296
Query: 250 -QILQERNELKAKVFLLKEELAYFQRELLTDHRVPGLLLEAMKVAVRKQRKKIKAKMLGT 308
Q L+ +L+ K +EE Q E E + +R+++++ + + L
Sbjct: 297 QQRLRREQQLRRK---QEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRR 353
Query: 309 PEEAESSEDE 318
+E E E +
Sbjct: 354 EQEEERREQQ 363
Score = 39.3 bits (90), Expect = 0.006
Identities = 38/153 (24%), Positives = 71/153 (46%), Gaps = 8/153 (5%)
Query: 60 RALELLEQAAVGPAPDSLQVSAQPAEQELRRLREENERLRRELRAGPQEERALLRQLKEV 119
R ++LE+ + P + Q+ Q +++ R E+ + R E + QE R+ +++
Sbjct: 1745 RYRKILEEEQLRPEREEQQLRRQERDRKFRE-EEQLRQEREEQQLRSQESDRKFREEEQL 1803
Query: 120 T-DRQRDELRAHNRDLRQRGQETE-ALQEQLQRLLLVNAELRHKLAAMQTQLRAAQDRER 177
+R+ +LR RD + R +E + L+EQ QRL + R + + Q A Q++ R
Sbjct: 1804 RQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRL----RQERDRQYRAEEQF-ATQEKSR 1858
Query: 178 ERQQPGEAATPQAKERARGQAGRPGHQHGQEPE 210
+Q Q + + R + R H Q+ E
Sbjct: 1859 REEQELWQEEEQKRRQERERKLREEHIRRQQKE 1891
Score = 38.9 bits (89), Expect = 0.008
Identities = 63/297 (21%), Positives = 118/297 (39%), Gaps = 43/297 (14%)
Query: 82 QPAEQELRR-------LREENERLRRELRAGPQEERALLRQLKEVTDRQR--------DE 126
Q E+E RR E++ER R+ L A P RQL+ +QR +E
Sbjct: 757 QQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEE 816
Query: 127 LRAHNRDLRQRGQETEALQEQLQRLLLVNAELRHKLAAMQTQLRAAQDRERERQQPGE-- 184
R R+R +E + L+E+ Q L E +L + L+ Q+R R ++Q +
Sbjct: 817 KEQRRRQRREREKELQFLEEEEQ---LQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQK 873
Query: 185 ---AATPQAKERARGQAGRPGHQHGQEPEWATAGAGAPGNPEDPAEAAQQLGRPSEAGQC 241
+ K R +P Q E + E ++ + + +
Sbjct: 874 WRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREE 933
Query: 242 RFSREEFEQILQERNELKAKVFLLKEELAYFQRELLTDHRVPGLLLEAMKVAVRKQRKKI 301
++E EQ+L+E E + + +E ++++ + LL E + K+R++
Sbjct: 934 EQLQQEEEQLLREEREKRRR----QERERQYRKDKKLQQKEEQLLGEEPE----KRRRQE 985
Query: 302 KAKMLGTPEEAESSEDEAGPWILLSDDKGDHPPPPESKIQSFFGLWYRGKAESSEDE 358
+ K EE + E++ LL +++ E + + + YR K E ++E
Sbjct: 986 REKKYREEEELQQEEEQ-----LLREER-------EKRRRQEWERQYRKKDELQQEE 1030
Score = 38.5 bits (88), Expect = 0.011
Identities = 68/248 (27%), Positives = 107/248 (43%), Gaps = 42/248 (16%)
Query: 78 QVSAQPAEQELRRLREENERLRRELRAGPQEERALLRQLKEVTDRQRD-ELRAHNRDLRQ 136
Q+ Q EQ+LR R+ R +L EE+ L RQ ++ R+ + +LR R+ +
Sbjct: 1651 QLRRQEREQQLRHDRDRKFREEEQL-LQEGEEQQLRRQERDRKFREEEQQLRRQERERKF 1709
Query: 137 RGQETEALQEQLQRLLLVNAELRHKLAAMQTQLRAAQDRER----ERQQPGEAATPQAKE 192
+E + +++L+R +LR + Q QLR Q+R R E Q E Q +
Sbjct: 1710 LQEEQQLRRQELERKFREEEQLRQE--TEQEQLR-RQERYRKILEEEQLRPEREEQQLRR 1766
Query: 193 RARGQAGRPGHQHGQEPEWATAGAGAPGNPEDPAEAAQQLGRPSEAGQCRFSREEFEQIL 252
+ R + R Q QE E QQL R E+ R REE EQ+
Sbjct: 1767 QERDRKFREEEQLRQERE------------------EQQL-RSQESD--RKFREE-EQLR 1804
Query: 253 QERNELKAKVFLLKEELAYFQRELLTDHRVPGLLLEAMKVAVRKQR-KKIKA-KMLGTPE 310
QER E ++L QR+ L LE + +R++R ++ +A + T E
Sbjct: 1805 QEREE---------QQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQE 1855
Query: 311 EAESSEDE 318
++ E E
Sbjct: 1856 KSRREEQE 1863
Score = 38.5 bits (88), Expect = 0.011
Identities = 38/149 (25%), Positives = 64/149 (42%), Gaps = 17/149 (11%)
Query: 77 LQVSAQPAEQELRRLREENERLRRELR----AGPQEERALLRQLKEVTDRQRDELRAHNR 132
LQ Q QEL R E E+LR+E + R +L + + +R+ +LR R
Sbjct: 1710 LQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQER 1769
Query: 133 D--------LRQRGQETEALQEQLQRLLLVNAELRHKLAAMQTQLRAAQDRERERQQPGE 184
D LRQ +E + ++ R +LR + + QLR Q + R + +
Sbjct: 1770 DRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQE--REEQQLRPQQRDGKYRWEEEQ 1827
Query: 185 AATPQAKERARGQAGRPGHQHGQEPEWAT 213
+ ++R R + R Q+ E ++AT
Sbjct: 1828 LQLEEQEQRLRQERDR---QYRAEEQFAT 1853
Score = 37.7 bits (86), Expect = 0.019
Identities = 47/187 (25%), Positives = 85/187 (45%), Gaps = 22/187 (11%)
Query: 78 QVSAQPAEQELR-----RLREENERLRRELRAGP--QEERALLRQLKEVTDRQRDELRAH 130
Q+ Q EQ+LR + REE ++L R+ R +EE+ + RQ +E + +E +
Sbjct: 1398 QLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERE--RKFLEEEQQL 1455
Query: 131 NRDLRQRGQETEALQEQLQRLLLVNAELRHKLAAMQTQLRAAQDRERERQQPGEAATPQA 190
++ ++ +E E L ++ + L E K + QLR +ER+R+ + Q
Sbjct: 1456 RQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRR---QERDRKFREQELRSQE 1512
Query: 191 KERARGQAGRPGHQHGQEPEWATAGAGAPGNPEDPAEAAQQLGRPSEAGQCRFSREEFEQ 250
ER + + H+ ++ ++ E+ Q+ G+ + R REE EQ
Sbjct: 1513 PERKFLEEEQQLHRQQRQRKFL---------QEEQQLRRQERGQQRRQDRDRKFREE-EQ 1562
Query: 251 ILQERNE 257
+ QER E
Sbjct: 1563 LRQEREE 1569
Score = 37.4 bits (85), Expect = 0.024
Identities = 55/223 (24%), Positives = 91/223 (40%), Gaps = 30/223 (13%)
Query: 78 QVSAQPAEQELRRL--REENERLRRELRAGPQEERALLRQLKEVTDRQRDELRAHNRDLR 135
Q+ A+ +Q +R EE + RR R ++E L + +++ R+R + D
Sbjct: 797 QLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGL 856
Query: 136 QRGQETEALQEQLQ------RLLLVNAELRHKL---AAMQTQLRAAQ---DRERERQQPG 183
Q QE QEQ + +L RH L A+Q QLR Q E E Q
Sbjct: 857 QEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQRE 916
Query: 184 EAATPQAKERARGQAGRPGHQHGQEPEWATAGAGAPGNPEDPAEAAQQLGRPSEAGQCRF 243
E + +E+ R R Q QE E + E ++ R + + +
Sbjct: 917 EREKRRRQEQERQY--REEEQLQQEEEQLL---------REEREKRRRQERERQYRKDKK 965
Query: 244 SREEFEQILQE-----RNELKAKVFLLKEELAYFQRELLTDHR 281
+++ EQ+L E R + + K + +EEL + +LL + R
Sbjct: 966 LQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREER 1008
Score = 37.4 bits (85), Expect = 0.024
Identities = 55/226 (24%), Positives = 98/226 (43%), Gaps = 34/226 (15%)
Query: 85 EQELRRLREENERLRREL-RAGPQEERALLRQLKEVTDRQRDELRAHNRDLRQRGQETEA 143
E++ R +E ++LR++ R +EE+ L RQ +R R + R + +R++ +E +
Sbjct: 1395 EEQQLRCQEREQQLRQDRDRKFREEEQQLSRQ-----ERDR-KFREEEQQVRRQERERKF 1448
Query: 144 LQEQLQRLLLVNAELRHKLAAMQTQLRAAQDRERERQQPGE---AATPQAKERARGQAGR 200
L+E+ Q + E K + L+ ++++ RQ+ Q + + R + R
Sbjct: 1449 LEEEQQ----LRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFR 1504
Query: 201 PGHQHGQEPEWATAGAGAPGNPEDPAEAAQQLGRPSEAGQCRFSREEFEQILQERNELKA 260
QEPE E QQL R + Q +F +EE + QER + +
Sbjct: 1505 EQELRSQEPE------------RKFLEEEQQLHR--QQRQRKFLQEEQQLRRQERGQQRR 1550
Query: 261 ----KVFLLKEELAYFQRE--LLTDHRVPGLLLEAMKVAVRKQRKK 300
+ F +E+L + E L R LE KV ++Q +K
Sbjct: 1551 QDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERK 1596
Score = 35.4 bits (80), Expect = 0.092
Identities = 50/242 (20%), Positives = 101/242 (41%), Gaps = 30/242 (12%)
Query: 85 EQELRRLREENERLRRELRAGP------QEERALLRQLK---------EVTDRQRDELRA 129
EQ+LRR + + +ELR+ +EE+ L RQ + ++ ++R + R
Sbjct: 1491 EQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRR 1550
Query: 130 HNRDLRQRGQETEALQEQLQRLLLVNAELR-----HKLAAMQTQLRAAQDRERERQQPGE 184
+RD + R +E + + Q+L + + K+ + + + +D ++ R+Q G+
Sbjct: 1551 QDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQ 1610
Query: 185 AATPQAKERARGQAGRPGHQHGQEPEWATAGAGAPGNPEDPAEAAQQLGRPSEAGQCRFS 244
Q ++R + + Q +E + E+P QL R Q R
Sbjct: 1611 QQLRQERDR-KFREDEQLLQEREEQQLHRQERDRKFLEEEP-----QLRRQEREQQLRHD 1664
Query: 245 RE----EFEQILQERNELKAKVFLLKEELAYFQRELLTDHRVPGLLLEAMKVAVRKQRKK 300
R+ E EQ+LQE E + + + +++L R L E ++ ++ +K
Sbjct: 1665 RDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERK 1724
Query: 301 IK 302
+
Sbjct: 1725 FR 1726
Score = 30.0 bits (66), Expect = 3.9
Identities = 33/164 (20%), Positives = 70/164 (42%), Gaps = 3/164 (1%)
Query: 94 ENERLRRELRAGPQEERALLRQLKEVTDRQRDELRAHNRDLRQRGQETEALQEQLQRLLL 153
ENE+ R +L +R + L+ + Q++ R R Q+ +EQL+R
Sbjct: 1246 ENEQFR-QLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQ 1304
Query: 154 VNAELRHKLAAMQTQLRAAQDRERERQQPGEAATPQAKERARGQAGRPGHQHGQEPEWAT 213
A+ R + + + QL + E+ R+Q + + ++ + + +P + ++ ++
Sbjct: 1305 KEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFRE 1364
Query: 214 AGAGAPGNPEDPAEAAQQLGRPSEAGQCRFSREEFEQILQERNE 257
E Q+L R + + +F +EE + QER +
Sbjct: 1365 EELRHQEQGRKFLEEEQRLRR--QERERKFLKEEQQLRCQEREQ 1406
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 49.3 bits (116), Expect = 6e-06
Identities = 76/276 (27%), Positives = 120/276 (43%), Gaps = 32/276 (11%)
Query: 16 REAAGSASAAELVYHLAGALGTELQDLARRFGPEAAAGLVPLVVRALELLEQAA-VGPAP 74
R+ + S E AL +EL+DL R E AA VR L+ EQA +G
Sbjct: 1094 RQKRDAQSRQEQDRSTVNALTSELRDL--RAQREEAAAAHAQEVRRLQ--EQARDLGKQR 1149
Query: 75 DSLQVSAQPAEQELRRLREENERLRRELRAGPQEERALLRQLKEVTDRQRDELRAHNRDL 134
DS A+ +LR L + + LRREL E + LR+ +E + QR E R L
Sbjct: 1150 DSCLREAEELRTQLRLLEDARDGLRRELL----EAQRKLRESQEGREVQRQEAGELRRSL 1205
Query: 135 RQRGQETEALQ---EQLQ-----------RLLLVNAELRHKLAAMQTQLRAAQDRERERQ 180
+ +E EAL+ E+L+ L L N + KLA ++ + R A +E
Sbjct: 1206 GEGAKEREALRRSNEELRSAVKKAESERISLKLANEDKEQKLALLE-EARTAVGKEAGEL 1264
Query: 181 QPGEAATPQAKERARGQAGRPGHQHGQEPEWATAGAGAPGNPEDPAEAAQQLGRPSEAGQ 240
+ G Q ER+R +A R + ++ + + G + LG +E
Sbjct: 1265 RTG----LQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLALGERAE--- 1317
Query: 241 CRFSREEFEQILQERNELKAKVFLLKEELAYFQREL 276
+ SR E + Q + +A + ++++EL QR+L
Sbjct: 1318 -KESRRETLGLRQRLLKGEASLEVMRQELQVAQRKL 1352
Score = 48.9 bits (115), Expect = 8e-06
Identities = 60/222 (27%), Positives = 94/222 (42%), Gaps = 32/222 (14%)
Query: 3 PRRAAPG---VPGWGSREAAGSASAAELVYHLAGALGTELQDLARRFGPEAAAGLVPLVV 59
PRR++PG P G A +S L++ ++QD+ R+ EA+ L+ +
Sbjct: 496 PRRSSPGRGRSPRRGPSPACSDSSTLALIHSALHKRQLQVQDMRGRY--EASQDLLGTLR 553
Query: 60 RALE--------LLEQAA-VGPAPDSLQVSAQPAEQELRRLREENERLRRE-------LR 103
+ L L EQ + D + + A++E++RLR NE L RE L+
Sbjct: 554 KQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSNLAHSLQ 613
Query: 104 AGPQE------ERALLRQLKEVTDRQRDELRAHNRDLRQRG----QETEALQEQLQRLLL 153
Q+ ER L+ +E RQRD L D Q G +E E QL++L
Sbjct: 614 VAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEG 673
Query: 154 VNAELRHKLAAMQTQL-RAAQDRERERQQPGEAATPQAKERA 194
+ L +L ++ L RA R+ + + E A K A
Sbjct: 674 KRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEA 715
Score = 47.0 bits (110), Expect = 3e-05
Identities = 54/212 (25%), Positives = 95/212 (44%), Gaps = 12/212 (5%)
Query: 73 APDSLQVSAQPAEQELRRLREENERLRRELRAGPQEERALLRQLKEVTDRQRDELRAH-N 131
A SL+ E++L+RL+ E E REL A ERA QL+ R+++EL A
Sbjct: 980 AQASLREQRAAHEEDLQRLQREKEAAWRELEA----ERA---QLQSQLQREQEELLARLE 1032
Query: 132 RDLRQRGQETEALQEQLQR-LLLVNAELRHKLAAMQTQLRAAQDRERERQQPGEAATPQA 190
+ + +E ALQ++ LLL +E + L+ +++ A ++ + + +
Sbjct: 1033 AEKEELSEEIAALQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEM 1092
Query: 191 KERARGQAGRPGHQHGQEPEWATAGAGAPGNPEDPAEA-AQQLGRPSEAGQCRFSREEFE 249
+ + R R + E+ A A AQ++ R E Q R ++ +
Sbjct: 1093 ERQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAQEVRRLQE--QARDLGKQRD 1150
Query: 250 QILQERNELKAKVFLLKEELAYFQRELLTDHR 281
L+E EL+ ++ LL++ +RELL R
Sbjct: 1151 SCLREAEELRTQLRLLEDARDGLRRELLEAQR 1182
Score = 45.4 bits (106), Expect = 9e-05
Identities = 71/262 (27%), Positives = 103/262 (39%), Gaps = 52/262 (19%)
Query: 60 RALELLEQAA-----VGPAPDSLQVSAQPAEQELRRLREENERLRRELRAGPQEERALLR 114
R +E LE+AA + L V AE+E R L EE RLR E+ AL
Sbjct: 859 RQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATRLR-------LEKEALEG 911
Query: 115 QLKEVTDRQRDELRAHNRDLRQRGQETEALQEQLQRLLLVNAELRHKLAAMQTQLRAAQD 174
L EV R L Q E L+ + Q LLL L +LA ++ Q+ A Q+
Sbjct: 912 SLFEV-----------QRQLAQLEARREQLEAEGQALLLAKETLTGELAGLRQQIIATQE 960
Query: 175 RERERQQPGEAATPQAKERARGQAGRPGHQHGQEPEWATAGAGAPGNPEDPAEAAQQLGR 234
+ ++ QA+ A+ H E Q+L R
Sbjct: 961 KASLDKELMAQKLVQAEREAQASLREQRAAH--------------------EEDLQRLQR 1000
Query: 235 PSEAGQCRFSREEFE---QILQERNELKAKVFLLKEELAYFQRELLTDHRVPGLLL---E 288
EA E + Q+ +E+ EL A++ KEEL+ + L R GLLL E
Sbjct: 1001 EKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSE-EIAALQQERDEGLLLAESE 1059
Query: 289 AMKVAVRKQRKK--IKAKMLGT 308
+ K+ +K + K++GT
Sbjct: 1060 KQQALSLKESEKTALSEKLMGT 1081
Score = 43.9 bits (102), Expect = 3e-04
Identities = 47/156 (30%), Positives = 69/156 (44%), Gaps = 15/156 (9%)
Query: 62 LELLEQA--AVGPAPDSLQVSAQPAEQELRRLREENERLRRELRAGPQEERALLRQLKEV 119
L LLE+A AVG L+ Q E+ R E + LRR+++ E L R+L E+
Sbjct: 1247 LALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAEL 1306
Query: 120 T------DRQRDELRAHNRDLRQRGQETEA-LQEQLQRLLLVNAELRHKLAAMQTQLR-- 170
+R E R LRQR + EA L+ Q L + +L+ + +T+ R
Sbjct: 1307 QGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEFRTRERRL 1366
Query: 171 ---AAQDRERERQQPGEAATPQAK-ERARGQAGRPG 202
+ R E+QQ A + K E AR +A G
Sbjct: 1367 LGSLEEARGTEKQQLDHARGLELKLEAARAEAAELG 1402
Score = 42.7 bits (99), Expect = 6e-04
Identities = 72/251 (28%), Positives = 104/251 (41%), Gaps = 46/251 (18%)
Query: 76 SLQVSAQPAEQELRRLREENERLRRELRAGPQEERALLRQLKEVTDRQRDELRAHNRDLR 135
+LQ + AEQE REE ERL ELR E+ + RQ E + LR
Sbjct: 768 ALQGRQRQAEQEATVAREEQERLE-ELRL----EQEVARQGLEGS-------------LR 809
Query: 136 QRGQETEALQEQLQRLLLVNAELRHKLAAMQTQLRAAQDRERERQQPGEAATPQ--AKER 193
Q EAL++QL L ++L+ +LA + QL RE+E +Q A Q A ER
Sbjct: 810 VAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQL---SGREQELEQARREAQRQVEALER 866
Query: 194 ARGQAGRPGHQHGQEPEWATAGAGAPGNPEDPAEAAQQLGR--PSEAGQCRFSREEFEQI 251
A + +H AG AA++ GR EA + R +E E
Sbjct: 867 AAREKEALAKEH--------AGLAV------QLVAAEREGRTLSEEATRLRLEKEALEGS 912
Query: 252 LQERNELKAKVFLLKEEL-AYFQRELLTDHRVPGLLLEAMKVAVRKQRKK------IKAK 304
L E A++ +E+L A Q LL + G L + + Q K + K
Sbjct: 913 LFEVQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLRQQIIATQEKASLDKELMAQK 972
Query: 305 MLGTPEEAESS 315
++ EA++S
Sbjct: 973 LVQAEREAQAS 983
Score = 41.6 bits (96), Expect = 0.001
Identities = 56/199 (28%), Positives = 90/199 (45%), Gaps = 36/199 (18%)
Query: 36 GTELQDLARRFGPEAAAGLV-PLVVRALELLEQAAVGPAPD-----SLQVSAQPAEQELR 89
G +DLA+ + L+ +V R L E + PA + SLQ Q +QEL
Sbjct: 32 GLGARDLAQDAQITSLPALIREIVTRNLSQPESPVLLPATEMASLLSLQEENQLLQQELS 91
Query: 90 RL----------REE--------NERLRRELRAGP-----QEERALLRQLKEVTDRQRDE 126
R+ R+E +ERL + LR P QE R L+RQ E+ + ++E
Sbjct: 92 RVEDLLAQSRAERDELAIKYNAVSERLEQALRLEPGELETQEPRGLVRQSVELRRQLQEE 151
Query: 127 LRAHNRDLR--QRGQETEA-LQEQLQRLLLVN----AELRHKLAAMQTQLRAAQDRERER 179
++ R L+ Q GQ+ +A L ++LQ +L +EL +L +L + R+ E
Sbjct: 152 QASYRRKLQAYQEGQQRQAQLVQRLQGKILQYKKRCSELEQQLLERSGELEQQRLRDTEH 211
Query: 180 QQPGEAATPQAKERARGQA 198
Q E+A + +E + A
Sbjct: 212 SQDLESALIRLEEEQQRSA 230
Score = 34.7 bits (78), Expect = 0.16
Identities = 55/222 (24%), Positives = 93/222 (41%), Gaps = 48/222 (21%)
Query: 94 ENERLRRELRAGPQEER----ALLRQLKEVTDRQRDELRAHNRDLRQRGQETEALQEQLQ 149
E ER +R+ ++ +++R AL +L+++ ++ + AH QE LQEQ +
Sbjct: 1091 EMERQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAAAAH-------AQEVRRLQEQAR 1143
Query: 150 RL-------------------LLVNAE--LRHKLAAMQTQLRAAQD-RERERQQPGEAAT 187
L LL +A LR +L Q +LR +Q+ RE +RQ+ GE
Sbjct: 1144 DLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRR 1203
Query: 188 PQAKERARGQAGRPGHQH------GQEPEWATAGAGAPGNPEDPA---EAAQQLGRPSEA 238
+ +A R ++ E E + + A EA +G+ EA
Sbjct: 1204 SLGEGAKEREALRRSNEELRSAVKKAESERISLKLANEDKEQKLALLEEARTAVGK--EA 1261
Query: 239 GQCRFSREEFE----QILQERNELKAKVFLLKEELAYFQREL 276
G+ R +E E + +E EL+ ++ +L E REL
Sbjct: 1262 GELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGREL 1303
Score = 32.0 bits (71), Expect = 1.0
Identities = 41/162 (25%), Positives = 73/162 (45%), Gaps = 19/162 (11%)
Query: 32 AGALGTELQDLARRFGP-EAAAGLVPLVVR----ALELLEQA--AVGPAPDSLQVSAQPA 84
A AL + L R+ E AG + L V AL +E++ A+ L + +
Sbjct: 1679 AQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQS 1738
Query: 85 EQELRRLREENERLRRELRAGPQEERALLRQLKEVTDRQRDELRAHNRDLRQRGQETEAL 144
L R++N L++ L A + + L ++ L A + L + +++ +L
Sbjct: 1739 SASLNSTRDKNLHLQKALTACEHDRQVL-----------QERLDAARQALSEARKQSSSL 1787
Query: 145 QEQLQRLLLVNAELRHKLAAMQTQLRAAQDRERERQQPGEAA 186
EQ+Q L A+L + + QL+ ++ R+RQ+ GEAA
Sbjct: 1788 GEQVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQE-GEAA 1828
Score = 30.8 bits (68), Expect = 2.3
Identities = 56/278 (20%), Positives = 100/278 (35%), Gaps = 38/278 (13%)
Query: 66 EQAAVGPAPDSLQVSAQPAEQELRRLREENERLRREL------RAGPQEERALLRQLKEV 119
E+A V A + E + +LR E L+ L +++ L +L
Sbjct: 702 EKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQ 761
Query: 120 TDRQRDELRAHNRDLRQRGQETEALQEQLQRLLLVNAELRHKLAAMQTQLRAAQDRER-- 177
+ ++ L+ R Q QE+L+ L L R ++ LR A+ +
Sbjct: 762 LEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQ---GLEGSLRVAEQAQEAL 818
Query: 178 ERQQPGEAATPQAKERARGQAGRPGHQHGQEPEWATAGAGAPGNPEDPAEAAQQLGRPSE 237
E+Q P + Q R QE E A A + EA ++ R E
Sbjct: 819 EQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREA------QRQVEALERAAREKE 872
Query: 238 A----------------GQCRFSREEFEQILQERNELKAKVFLLKEELAYFQ--RELLTD 279
A + R EE ++ E+ L+ +F ++ +LA + RE L
Sbjct: 873 ALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQL-- 930
Query: 280 HRVPGLLLEAMKVAVRKQRKKIKAKMLGTPEEAESSED 317
G L K + + ++ +++ T E+A ++
Sbjct: 931 -EAEGQALLLAKETLTGELAGLRQQIIATQEKASLDKE 967
Score = 30.4 bits (67), Expect = 3.0
Identities = 40/136 (29%), Positives = 60/136 (44%), Gaps = 16/136 (11%)
Query: 75 DSLQVSAQPAEQELRRLREENERLRRE---LRAGPQEERALLRQLKEVTDRQRDELRAHN 131
D+ + + A ++ L E+ + LR E L E L+QL+EV RQR E A
Sbjct: 1771 DAARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQLREVL-RQRQEGEAAA 1829
Query: 132 RDLRQRGQ-ETEALQEQLQRLLLVNAELR-HKLAAMQTQLRAAQDR----------ERER 179
+ Q+ Q E LQE+L L A+L K ++ LR +DR ERE+
Sbjct: 1830 LNTVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREK 1889
Query: 180 QQPGEAATPQAKERAR 195
+ E + E+ R
Sbjct: 1890 LRSHEDTVRLSAEKGR 1905
>gi|210032790 hypothetical protein LOC27146 [Homo sapiens]
Length = 1060
Score = 49.3 bits (116), Expect = 6e-06
Identities = 57/252 (22%), Positives = 109/252 (43%), Gaps = 20/252 (7%)
Query: 77 LQVSAQPAEQELRRLREEN-----ERLRRELRAGPQEERALLR-QLKEVTDRQRDELRAH 130
L+ S Q A + L + R + ERL++E Q + R +L+ + ++ R EL+
Sbjct: 659 LEASHQRALRMLEKARHQELKATEERLKKESSHSLQIQHQTHRLELQALEEKARQELQEE 718
Query: 131 NRDLR-QRGQETEALQEQLQRLLLVNAELRHKLAAMQTQLRAAQDRERERQQPGEAATPQ 189
++ Q+ E+L+++L + + L A+Q +LRA ++ Q PG++
Sbjct: 719 RERMQAQQALLLESLRQELSEQQAACSGHQKDLEALQAELRALGRQQASSQCPGDSKDHI 778
Query: 190 AKERARGQAGRPGHQHGQEPEWATAGAGAPGNPEDPAEAAQQLGRPSEAGQCRFSREEFE 249
RG G+ G G + + G G +A ++L R E E
Sbjct: 779 IATEERGGPGQAGSPPGAAGQGSGEGCGLWEENAQLQDAVRRL------------RAEVE 826
Query: 250 QILQERNELK-AKVFLLKEELAYFQRELLTDHRVPGLLLEAMKVAVRKQRKKIKAKMLGT 308
Q QE +L+ + FL + + A RE+ T + ++AM + +++A++
Sbjct: 827 QHQQEAQKLRDQRRFLEETQQAQRAREVETLRQEHRKEMQAMVADFSSAQAQLQARLAAL 886
Query: 309 PEEAESSEDEAG 320
E + S ++ G
Sbjct: 887 EAELKDSGEKPG 898
Score = 38.5 bits (88), Expect = 0.011
Identities = 47/253 (18%), Positives = 109/253 (43%), Gaps = 24/253 (9%)
Query: 78 QVSAQPAEQELRRLREENERLRRELRAGPQEERALLRQLK---EVTDRQRDELRAHNRDL 134
Q Q Q L + +E+ LR+ + +A +R+L+ E R+ +L+ + + L
Sbjct: 234 QAMQQSVSQALWQWQEKESDLRKNFQVQESALQAQVRKLEGDLEHRGRKISDLKKYAQKL 293
Query: 135 RQRGQETEALQEQLQRLLLVNAELRHKLAAMQTQLRAAQDRERERQQPGEAATPQAKERA 194
++R Q+ L QL+ N+EL+ + +L A+DR ++ G T K
Sbjct: 294 KERIQD---LDVQLKEARQENSELKGTAKKLGEKLAVAKDRMMLQECRGTQQTDAMKTEL 350
Query: 195 RGQAG--------RPGHQHGQEPEWATAGAGAPGNPEDPAEAAQQLGRPSEAGQCRFSRE 246
+ G+ H Q+ + D + + + + ++
Sbjct: 351 VSENKVLREENDLEAGNLHPQQDQSCLKECPCMKGGTD------MQTKKEASAETEYMKQ 404
Query: 247 EFEQILQE-RNELKAKVFLLKEELAYFQRELLTDHRVPGLLLEAMKVAVRKQRKKIKAKM 305
++E+ L++ +++ + + LK++L +L+ H V +++++ +V +RKK++ ++
Sbjct: 405 QYEEDLRKIKHQTEEEKKHLKDQLVKRLEDLVKKHTVE---IKSVRSSVEAERKKLQREV 461
Query: 306 LGTPEEAESSEDE 318
EE ++
Sbjct: 462 EAQLEEVRKKSEK 474
Score = 33.9 bits (76), Expect = 0.27
Identities = 53/264 (20%), Positives = 106/264 (40%), Gaps = 10/264 (3%)
Query: 49 EAAAGLVPLVVRALELLEQAAVGPAPDSLQVSAQPAEQELRRLREENERLRRELRAGPQE 108
EA + + ALEL ++ +S + E+ELR E ER+ R +
Sbjct: 95 EALLQRIQALESALELQKRLTEEALAESASCRLETKERELRVEAEHAERVLTLSREMLEL 154
Query: 109 ERALLRQLKEVTDRQ---RDELRAHNRDLRQ---RGQETEALQEQLQRLLLVNAELRHKL 162
+ R+L+ +T + + L + + + +G E + + ++QRL + N +L
Sbjct: 155 KADYERRLQHLTSHEATPQGRLPQESPETKSEPGQGPEMQEVLLEVQRLRVENQQLSKDY 214
Query: 163 AAMQTQLRAAQDRERE--RQQPGEAATPQAKERARGQAGRPGHQHGQEPEWATAGAGAPG 220
A +L+A +RE E RQ ++ + + ++ + QE G
Sbjct: 215 ARKAEELQATYERENEAIRQAMQQSVSQALWQWQEKESDLRKNFQVQESALQAQVRKLEG 274
Query: 221 NPEDPAEAAQQLGRPSEAGQCRFS--REEFEQILQERNELKAKVFLLKEELAYFQRELLT 278
+ E L + ++ + R + ++ QE +ELK L E+LA + ++
Sbjct: 275 DLEHRGRKISDLKKYAQKLKERIQDLDVQLKEARQENSELKGTAKKLGEKLAVAKDRMML 334
Query: 279 DHRVPGLLLEAMKVAVRKQRKKIK 302
+AMK + + K ++
Sbjct: 335 QECRGTQQTDAMKTELVSENKVLR 358
>gi|46592991 GRIP1 associated protein 1 isoform 1 [Homo sapiens]
Length = 841
Score = 48.9 bits (115), Expect = 8e-06
Identities = 64/266 (24%), Positives = 112/266 (42%), Gaps = 37/266 (13%)
Query: 64 LLEQAAVGPAPDSLQVSAQPAEQELRRLREENERLRRELRAGPQEERALLRQLKEVTDRQ 123
L E A+ + +L+ QEL LRE+ L EL+ E L+ Q ++ +
Sbjct: 332 LAENNALRTSLAALEQIQTAKTQELNMLREQTTGLAAELQQQQAEYEDLMGQKDDLNSQL 391
Query: 124 RDELRAHNR---DLRQRGQETEALQEQLQRLLLVNAELRHKLAAMQTQLRAAQDRERERQ 180
++ LRA++R L++ GQE E L ++LQ +AE R K + + Q++ + ++
Sbjct: 392 QESLRANSRLLEQLQEIGQEKEQLTQELQE-ARKSAEKR-KAMLDELAMETLQEKSQHKE 449
Query: 181 QPGEAATPQAKE----RARGQAG-RPGHQHGQEPEWATAGAGAPGNPEDPAEAAQQLGRP 235
+ G KE RAR + R H ED ++L
Sbjct: 450 ELGAVRLRHEKEVLGVRARYERELRELH-------------------EDKKRQEEEL--- 487
Query: 236 SEAGQCRFSR---EEFEQILQERNELKAKVFLLKEELAYFQRELLTDHRVPGLLLEAMKV 292
GQ R + E E + Q EL+A+V + +F+R L + +
Sbjct: 488 --RGQIREEKARTRELETLQQTVEELQAQVHSMDGAKGWFERRLKEAEESLQQQQQEQEE 545
Query: 293 AVRKQRKKIKAKMLGTPEEAESSEDE 318
A+++ R++ A++ G EE + D+
Sbjct: 546 ALKQCREQHAAELKGKEEELQDVRDQ 571
Score = 35.8 bits (81), Expect = 0.071
Identities = 58/265 (21%), Positives = 108/265 (40%), Gaps = 37/265 (13%)
Query: 62 LELLEQAAVGPAPDSLQVSAQPAEQELRRLREENERLRRELRAGPQEERALLRQLKEVTD 121
L+ ++ + + ++ Q E + + ++L++EL A Q L E+ D
Sbjct: 245 LQTEKETLFNDSRNKIEELQQRKEADHKAQLARTQKLQQELEAANQS-------LAELRD 297
Query: 122 RQRDELRAHNRDLR----QRGQETEALQEQLQRLLLVNAELRHKLAAMQTQLRAAQDRE- 176
+++ E H LR Q ++ QEQ++ LL N LR LAA++ Q++ A+ +E
Sbjct: 298 QRQGERLEHAAALRALQDQVSIQSADAQEQVEGLLAENNALRTSLAALE-QIQTAKTQEL 356
Query: 177 ---RERQQPGEAATPQAKERARGQAGRPGHQHGQEPEWATAGAGAPGNPEDPAEAAQQLG 233
RE+ A Q + G+ + Q E A + E Q++G
Sbjct: 357 NMLREQTTGLAAELQQQQAEYEDLMGQKDDLNSQLQESLRANSRL-------LEQLQEIG 409
Query: 234 RPSEAGQCRFSREEFEQILQERNELKAKVFLLKEELAYFQRELLTDHRVPGLLLEAMKVA 293
+ +E+ Q LQE + K + +ELA + + H+ E V
Sbjct: 410 Q---------EKEQLTQELQEARKSAEKRKAMLDELAMETLQEKSQHKE-----ELGAVR 455
Query: 294 VRKQRKKIKAKMLGTPEEAESSEDE 318
+R +++ + + E E ED+
Sbjct: 456 LRHEKEVLGVRARYERELRELHEDK 480
Score = 32.0 bits (71), Expect = 1.0
Identities = 51/231 (22%), Positives = 93/231 (40%), Gaps = 59/231 (25%)
Query: 73 APDSLQVSAQPAEQELRRLREEN--------ERLR--RELRAGPQEER--------ALLR 114
A +SLQ Q E+ L++ RE++ E L+ R+ QEER +L +
Sbjct: 532 AEESLQQQQQEQEEALKQCREQHAAELKGKEEELQDVRDQLEQAQEERDCHLKTISSLKQ 591
Query: 115 QLKEVTDRQR-------DELRAHNRDLRQRGQETEALQEQLQRLLLVNAELRHKLAAMQT 167
++K+ D QR L+ R L + + LQE+LQ +L N++ R L
Sbjct: 592 EVKDTVDGQRILEKKGSAALKDLKRQLHLERKRADKLQERLQD-ILTNSKSRSGL----E 646
Query: 168 QLRAAQDRERERQQPGEAATPQAKE-----RARGQAGRPGHQHGQEPEWATAGAGAPGNP 222
+L ++ R Q G++++ + R + + P P+ P
Sbjct: 647 ELVLSEMNSPSRTQTGDSSSISSFSYREILREKESSAVPARSLSSSPQ---------AQP 697
Query: 223 EDPAEAAQQLGRPSEAGQCRFSREEFEQILQERNELKAKVFLLKEELAYFQ 273
PAE S EE ++ Q E + + ++L+E++ + +
Sbjct: 698 PRPAE---------------LSDEEVAELFQRLAETQQEKWMLEEKVKHLE 733
Score = 30.0 bits (66), Expect = 3.9
Identities = 33/167 (19%), Positives = 65/167 (38%), Gaps = 14/167 (8%)
Query: 89 RRLREENERLRRELRAGPQEERALLRQLKEVTDRQRDELRAHNRDLRQRGQETEALQEQL 148
RRL+E E L+++ QE+ L+Q +E + EL+ +L+ + E QE+
Sbjct: 527 RRLKEAEESLQQQ----QQEQEEALKQCRE---QHAAELKGKEEELQDVRDQLEQAQEER 579
Query: 149 QRLLLVNAELRHKLAAMQTQLRAAQDRERERQQPGEAATPQAKERARGQAGRPGHQHGQE 208
L +++++ +++ D +R ++ G AA K + + R +
Sbjct: 580 DCHL-------KTISSLKQEVKDTVDGQRILEKKGSAALKDLKRQLHLERKRADKLQERL 632
Query: 209 PEWATAGAGAPGNPEDPAEAAQQLGRPSEAGQCRFSREEFEQILQER 255
+ T G E R S + +IL+E+
Sbjct: 633 QDILTNSKSRSGLEELVLSEMNSPSRTQTGDSSSISSFSYREILREK 679
>gi|194578896 golgi autoantigen, golgin subfamily a, 8E [Homo
sapiens]
Length = 430
Score = 48.5 bits (114), Expect = 1e-05
Identities = 56/221 (25%), Positives = 96/221 (43%), Gaps = 17/221 (7%)
Query: 55 VPLVVRALELLEQAAVGPAPDSLQVSAQPAEQELRRLREENERLRRELRAGPQEERALLR 114
V + R+L L+ P P + A P+E EL+ LR+E ER+ L+A + +
Sbjct: 72 VETLERSLSKLKHQMAEPLPP--EPPAVPSEVELQHLRKELERVAGALQAQVEYN----Q 125
Query: 115 QLKEVTDRQRDELRAHNRDLRQRGQETEALQEQLQRLLLVNAELRHKLAAMQTQLRAAQD 174
++ + + Q++ LR L+++ + +E+LQ+L AE ++ + + ++
Sbjct: 126 RISLLNEGQKERLREQEERLQEQQERLREQEERLQQL----AEPQNSFKELNNENKSVLQ 181
Query: 175 RERERQQPGEAATPQAKERARGQAGRPGHQHGQEPEWATAGAGAPGNPEDP--AEAAQQL 232
E QQ E KER + + Q A G G G D EA + +
Sbjct: 182 LE---QQVKELQEKLGKERLEAASQQKQQLTAQLSLMALPGEGHGGEHLDSEGEEAPRPM 238
Query: 233 GRPSEAGQCRFSREEFEQILQERNELKAKVFLLKEELAYFQ 273
E + R + F L+E+ +L V KEEL +FQ
Sbjct: 239 PSVPEDLESREAMSGFMDHLEEKADLSELV--EKEELGFFQ 277
>gi|239745111 PREDICTED: Golgin subfamily A member 8-like protein 3
isoform 1 [Homo sapiens]
Length = 632
Score = 48.1 bits (113), Expect = 1e-05
Identities = 45/175 (25%), Positives = 79/175 (45%), Gaps = 15/175 (8%)
Query: 60 RALELLEQAAVGPAPDSLQVSAQPAEQELRRLREENERLRRELRAGPQEERALLRQLKEV 119
R+L L+ P P + A P+E EL+ LR+E ER+ EL+A + +++ +
Sbjct: 282 RSLSKLKNQMAEPLPP--EPPAVPSEVELQHLRKELERVAGELQAQVKNN----QRISLL 335
Query: 120 TDRQRDELRAHNRDLRQRGQETEALQEQLQRLLLVNAELR----HKLAAMQTQLRAAQDR 175
RQ + +R LR++ + + + LQ+L + + A+Q + + + +
Sbjct: 336 NQRQEERIREQEERLRKQEERIQEQHKSLQQLAKPQSVFKEPNNENKNALQLEQQVKELQ 395
Query: 176 ERERQQPGEAATPQAKERAR--GQAGRPGHQHGQE---PEWATAGAGAPGNPEDP 225
E+ ++ EAA+ Q ++ PG HG E E A P PEDP
Sbjct: 396 EKLGEEHLEAASQQNQQLTAQLSLMALPGEGHGGEHLDSEGEEAPRPMPSVPEDP 450
Score = 30.8 bits (68), Expect = 2.3
Identities = 42/216 (19%), Positives = 92/216 (42%), Gaps = 21/216 (9%)
Query: 110 RALLRQLKEVTDRQRDELRAHNRDLRQRGQETEALQEQLQRLLLVNAELRHKLAAMQTQL 169
++L +Q K+V + +E +A+N+ + + L+ Q+Q L + EL L M+ L
Sbjct: 101 KSLKQQKKQVEHQLEEEKKANNKKQKAK----RVLEVQIQTLNIQKEELNTDLYHMKRSL 156
Query: 170 RAAQDRERE--------RQQPGEAATPQAKERA--RGQAGRPGHQHGQEPEWATAGAGAP 219
R +++ ++ Q+ GE + + A + +A + + EW
Sbjct: 157 RYFEEKSKDLAVRLQHSLQRKGELESVLSNVMATQKKKANQLSSRSKARTEWK-----LE 211
Query: 220 GNPEDPAEAAQQLGRPSEA-GQCRFSREEFEQILQ-ERNELKAKVFLLKEELAYFQRELL 277
+ + A QL + E+ Q + R+E+ + L+ ER + ++ + +E+ ++E
Sbjct: 212 QSMREEALLKVQLTQFKESFQQVQLERDEYSEHLKGERARWQQRMRKMSQEICTLKKEKQ 271
Query: 278 TDHRVPGLLLEAMKVAVRKQRKKIKAKMLGTPEEAE 313
D R L ++ + + + + P E E
Sbjct: 272 QDMRRVEKLERSLSKLKNQMAEPLPPEPPAVPSEVE 307
>gi|56549694 enabled homolog isoform a [Homo sapiens]
Length = 591
Score = 47.8 bits (112), Expect = 2e-05
Identities = 51/186 (27%), Positives = 76/186 (40%), Gaps = 30/186 (16%)
Query: 63 ELLEQAAVGPAPDSL-----QVSAQPAEQELRRLREENERLRRELRAGPQEERALLRQLK 117
+L Q GP+ + L Q+ Q ++EL R R E ER+ RE + ER L + +
Sbjct: 126 QLPAQVQNGPSQEELEIQRRQLQEQQRQKELERERLERERMERE-----RLERERLERER 180
Query: 118 EVTDRQRDELRAHNRDLRQRGQETEALQEQLQRLLLVNAELRHKLAAMQTQLRAAQDRER 177
+R E R R+R QE QE+L+R Q +L + +R
Sbjct: 181 LERERLEQEQLERERQERER-QERLERQERLER---------------QERLERQERLDR 224
Query: 178 ERQQPGEAATPQAKERARGQAGRPGHQHGQEPEW----ATAGAGAPGNPEDPAEAAQQLG 233
ERQ+ E + ER R + R ++ EW + A AP + E P +
Sbjct: 225 ERQERQERERLERLERERQERERQEQLEREQLEWERERRISSAAAPASVETPLNSVLGDS 284
Query: 234 RPSEAG 239
SE G
Sbjct: 285 SASEPG 290
Score = 39.3 bits (90), Expect = 0.006
Identities = 67/326 (20%), Positives = 116/326 (35%), Gaps = 74/326 (22%)
Query: 58 VVRALELLEQAAVGPAPDSLQVSAQPAEQELRRLREENERLRRELRAGPQEERALLRQLK 117
++ ALE+L GP L +N +L +++ GP +E + Q +
Sbjct: 104 MMHALEVLNSQETGPT-----------------LPRQNSQLPAQVQNGPSQEELEI-QRR 145
Query: 118 EVTDRQRDELRAHNRDLRQRGQETEALQEQLQRLLLVNAELRHKLAAMQTQLRAAQDRER 177
++ ++QR + R R+R + +E+L+R L L Q QL ER
Sbjct: 146 QLQEQQRQKELERERLERERMERERLERERLERERLERERLE------QEQL------ER 193
Query: 178 ERQQPGEAATPQAKERARGQAGRPGHQHGQEPEWATAGAGAPGNPEDPAEAAQQLGRPSE 237
ERQ+ + +ER Q E ++ R
Sbjct: 194 ERQERERQERLERQERLERQ-----------------------------ERLERQERLDR 224
Query: 238 AGQCRFSREEFEQILQERNELKAKVFLLKEELAYFQRELLTDHRVPGLLLEAMKVAVRKQ 297
Q R RE E++ +ER E + + L +E+L + + ++ P +++ +
Sbjct: 225 ERQERQERERLERLERERQERERQEQLEREQLEWERERRISSAAAPA----SVETPLNSV 280
Query: 298 RKKIKAKMLGTPEEAESSEDEAGPWILLSDDKGDHPPPPESKIQSFFGLWYRGKAESSED 357
A G ++ +E + I+L G PPP + G A++S
Sbjct: 281 LGDSSASEPGLQAASQPAETPSQQGIVL----GPLAPPPPPPLPP-------GPAQASVA 329
Query: 358 ETSSPAPSKLGGEEEAQPQSPAPDPP 383
P P P P P PP
Sbjct: 330 LPPPPGPPPPPPLPSTGPPPPPPPPP 355
>gi|39930375 enabled homolog isoform b [Homo sapiens]
Length = 570
Score = 47.8 bits (112), Expect = 2e-05
Identities = 51/186 (27%), Positives = 76/186 (40%), Gaps = 30/186 (16%)
Query: 63 ELLEQAAVGPAPDSL-----QVSAQPAEQELRRLREENERLRRELRAGPQEERALLRQLK 117
+L Q GP+ + L Q+ Q ++EL R R E ER+ RE + ER L + +
Sbjct: 126 QLPAQVQNGPSQEELEIQRRQLQEQQRQKELERERLERERMERE-----RLERERLERER 180
Query: 118 EVTDRQRDELRAHNRDLRQRGQETEALQEQLQRLLLVNAELRHKLAAMQTQLRAAQDRER 177
+R E R R+R QE QE+L+R Q +L + +R
Sbjct: 181 LERERLEQEQLERERQERER-QERLERQERLER---------------QERLERQERLDR 224
Query: 178 ERQQPGEAATPQAKERARGQAGRPGHQHGQEPEW----ATAGAGAPGNPEDPAEAAQQLG 233
ERQ+ E + ER R + R ++ EW + A AP + E P +
Sbjct: 225 ERQERQERERLERLERERQERERQEQLEREQLEWERERRISSAAAPASVETPLNSVLGDS 284
Query: 234 RPSEAG 239
SE G
Sbjct: 285 SASEPG 290
Score = 39.3 bits (90), Expect = 0.006
Identities = 67/326 (20%), Positives = 116/326 (35%), Gaps = 74/326 (22%)
Query: 58 VVRALELLEQAAVGPAPDSLQVSAQPAEQELRRLREENERLRRELRAGPQEERALLRQLK 117
++ ALE+L GP L +N +L +++ GP +E + Q +
Sbjct: 104 MMHALEVLNSQETGPT-----------------LPRQNSQLPAQVQNGPSQEELEI-QRR 145
Query: 118 EVTDRQRDELRAHNRDLRQRGQETEALQEQLQRLLLVNAELRHKLAAMQTQLRAAQDRER 177
++ ++QR + R R+R + +E+L+R L L Q QL ER
Sbjct: 146 QLQEQQRQKELERERLERERMERERLERERLERERLERERLE------QEQL------ER 193
Query: 178 ERQQPGEAATPQAKERARGQAGRPGHQHGQEPEWATAGAGAPGNPEDPAEAAQQLGRPSE 237
ERQ+ + +ER Q E ++ R
Sbjct: 194 ERQERERQERLERQERLERQ-----------------------------ERLERQERLDR 224
Query: 238 AGQCRFSREEFEQILQERNELKAKVFLLKEELAYFQRELLTDHRVPGLLLEAMKVAVRKQ 297
Q R RE E++ +ER E + + L +E+L + + ++ P +++ +
Sbjct: 225 ERQERQERERLERLERERQERERQEQLEREQLEWERERRISSAAAPA----SVETPLNSV 280
Query: 298 RKKIKAKMLGTPEEAESSEDEAGPWILLSDDKGDHPPPPESKIQSFFGLWYRGKAESSED 357
A G ++ +E + I+L G PPP + G A++S
Sbjct: 281 LGDSSASEPGLQAASQPAETPSQQGIVL----GPLAPPPPPPLPP-------GPAQASVA 329
Query: 358 ETSSPAPSKLGGEEEAQPQSPAPDPP 383
P P P P P PP
Sbjct: 330 LPPPPGPPPPPPLPSTGPPPPPPPPP 355
>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
Length = 2003
Score = 47.8 bits (112), Expect = 2e-05
Identities = 74/278 (26%), Positives = 121/278 (43%), Gaps = 72/278 (25%)
Query: 67 QAAVGPAPDSLQ---VSAQPAEQELRRLREENERLRRELR-----AGPQEERALLRQLKE 118
QAA+ A + L+ V+ AE++ R L EE E LR EL Q+E R+ +E
Sbjct: 1142 QAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKRE-QE 1200
Query: 119 VTDRQR---DELRAHN---RDLRQR-GQETEALQEQLQ------------RLLLVN--AE 157
VT+ ++ +E R H ++LRQR GQ L EQL+ RL L +E
Sbjct: 1201 VTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSE 1260
Query: 158 LRHKLAAMQTQLRAAQDRERERQQPGEAATPQAKERARGQAGRPGHQHGQEPEWATAGAG 217
LR +L+++QT + + R R + + +A + R +
Sbjct: 1261 LRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERAR-------------------- 1300
Query: 218 APGNPEDPAEAAQQLGRPSEAGQCRFSREEFEQILQERNELKAKVFLLKEELAYFQRELL 277
AEAA++L R ++ E E + NE ++K L +EL+ + +L
Sbjct: 1301 --------AEAAEKLQR---------AQAELENVSGALNEAESKTIRLSKELSSTEAQL- 1342
Query: 278 TDHRVPGLLLE--AMKVAVRKQRKKIKAKMLGTPEEAE 313
H LL E K+A+ + + ++A+ G E+ E
Sbjct: 1343 --HDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLE 1378
Score = 45.8 bits (107), Expect = 7e-05
Identities = 78/303 (25%), Positives = 123/303 (40%), Gaps = 55/303 (18%)
Query: 58 VVRALELLEQA-AVGPAPDSLQVSAQPAEQELRRLREENERLRRELRAGPQEERALLRQL 116
V+RA+E E+A A G ++ +S A +E + REE ER R LRA E ALL
Sbjct: 1489 VLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRA---ELEALLSS- 1544
Query: 117 KEVTDRQRDELRAHNRDLRQRGQETEALQEQLQRLLLVNAELRHKLAAMQTQLRAAQDRE 176
K+ + EL R Q + A +L+ L + + +L L+ +R+
Sbjct: 1545 KDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERD 1604
Query: 177 RE-RQQPGEAATPQ---------------AKERARGQAGR---PGHQHGQEPEWATAGAG 217
+ R + GE Q K+R A R G + + A+AG G
Sbjct: 1605 LQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQG 1664
Query: 218 APGNPEDPAEAAQQLGRPS--------EAGQCRFSREE-FEQILQERNELK---AKVFLL 265
EA +QL + E + R SREE F Q + LK A+V L
Sbjct: 1665 -------KEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRL 1717
Query: 266 KEEL---------AYFQRELLTDHRVPGLLLEAMKVAVRKQRKKIKAKMLGTPEEAESSE 316
+EEL A R+ + D G L K A+ +++++++ ++ EE E +
Sbjct: 1718 QEELAASDRARRQAQQDRDEMADEVANGNL---SKAAILEEKRQLEGRLGQLEEELEEEQ 1774
Query: 317 DEA 319
+
Sbjct: 1775 SNS 1777
Score = 39.7 bits (91), Expect = 0.005
Identities = 82/345 (23%), Positives = 124/345 (35%), Gaps = 47/345 (13%)
Query: 61 ALELLEQA-----AVGPAPDSLQVSAQPAEQELRRLREENERLRRELRAGPQEERALLRQ 115
A ELL++ A+G +++ A ++L ER REL Q +A L +
Sbjct: 1345 AQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGREL----QTAQAQLSE 1400
Query: 116 LKEVTDRQRDELRAHNRDLRQRGQETEALQEQLQRLLLVNAELRHKLAAMQTQL-RAAQD 174
+ + + L A R+ +E EAL ++L L +Q +L A D
Sbjct: 1401 WRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMD 1460
Query: 175 RERERQQPGEAATPQAK-----------------ERARGQAGRPGHQHGQEPEWATAGAG 217
E++RQ Q K ER R +A G+E E
Sbjct: 1461 LEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEA------EGRERE--ARALS 1512
Query: 218 APGNPEDPAEAAQQLGRPSEAGQCRFSREEFEQILQERNELKAKVFLLKEELAYFQRELL 277
E+ EA ++L R Q R R E E +L ++++ V L E +
Sbjct: 1513 LTRALEEEQEAREELER-----QNRALRAELEALLSSKDDVGKSVHEL-ERACRVAEQAA 1566
Query: 278 TDHRVPGLLLEAMKVAVR--KQRKKIKAKMLGTPEEAE-SSEDEAGP---WILLSDDKGD 331
D R LE A K R ++ + L T E + DEAG L +
Sbjct: 1567 NDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDA 1626
Query: 332 HPPPPESKIQSFFGLWYRGKAESSEDETSSPAPSKLGGEEEAQPQ 376
E + Q + R K E +E + S G+EEA Q
Sbjct: 1627 EVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQ 1671
Score = 33.1 bits (74), Expect = 0.46
Identities = 45/189 (23%), Positives = 75/189 (39%), Gaps = 21/189 (11%)
Query: 35 LGTELQDLARRFGPEAA----------AGLVPLVVRALELLEQAAVGPAPDSLQVSAQPA 84
L ++Q+L R G E A A L + +A E LEQ V + A
Sbjct: 1815 LERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLV--RRA 1872
Query: 85 EQELRRLR---EENERLRRELRAGPQEERALLRQLKEVTDRQRDELRAHNRDLRQRGQET 141
E+ L+ + EE R+ +LR ++ ++QLK + +E R+ +E
Sbjct: 1873 EKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQREL 1932
Query: 142 EALQEQLQRLLLVNAELRHKLAAMQTQLRAAQDRERERQQPGEAATPQAKERARGQAGRP 201
E + E + + LR++L R+ R + G A+ +A+E +P
Sbjct: 1933 EDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEE------AQP 1986
Query: 202 GHQHGQEPE 210
G EPE
Sbjct: 1987 GSGPSPEPE 1995
Score = 31.6 bits (70), Expect = 1.3
Identities = 34/147 (23%), Positives = 63/147 (42%), Gaps = 5/147 (3%)
Query: 39 LQDLARRFGPEAAAGLVPLV-VRALELLEQAAVGPAPDSLQVSAQPAEQELRRLREENER 97
L+D F +AA + + L L +A + D L+ + QEL +L+ +
Sbjct: 1029 LEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLR-KEEKGRQELEKLKRRLDG 1087
Query: 98 LRRELRAGPQEERALLRQLKEVTDRQRDELRAHNRDLRQRGQETEALQEQLQRLLLVNAE 157
EL+ E++ +L+ R+ +EL+A L + E A + L+ L A
Sbjct: 1088 ESSELQEQMVEQQQRAEELRAQLGRKEEELQA---ALARAEDEGGARAQLLKSLREAQAA 1144
Query: 158 LRHKLAAMQTQLRAAQDRERERQQPGE 184
L ++++ A E++R+ GE
Sbjct: 1145 LAEAQEDLESERVARTKAEKQRRDLGE 1171
>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
Length = 1995
Score = 47.8 bits (112), Expect = 2e-05
Identities = 74/278 (26%), Positives = 121/278 (43%), Gaps = 72/278 (25%)
Query: 67 QAAVGPAPDSLQ---VSAQPAEQELRRLREENERLRRELR-----AGPQEERALLRQLKE 118
QAA+ A + L+ V+ AE++ R L EE E LR EL Q+E R+ +E
Sbjct: 1134 QAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKRE-QE 1192
Query: 119 VTDRQR---DELRAHN---RDLRQR-GQETEALQEQLQ------------RLLLVN--AE 157
VT+ ++ +E R H ++LRQR GQ L EQL+ RL L +E
Sbjct: 1193 VTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSE 1252
Query: 158 LRHKLAAMQTQLRAAQDRERERQQPGEAATPQAKERARGQAGRPGHQHGQEPEWATAGAG 217
LR +L+++QT + + R R + + +A + R +
Sbjct: 1253 LRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERAR-------------------- 1292
Query: 218 APGNPEDPAEAAQQLGRPSEAGQCRFSREEFEQILQERNELKAKVFLLKEELAYFQRELL 277
AEAA++L R ++ E E + NE ++K L +EL+ + +L
Sbjct: 1293 --------AEAAEKLQR---------AQAELENVSGALNEAESKTIRLSKELSSTEAQL- 1334
Query: 278 TDHRVPGLLLE--AMKVAVRKQRKKIKAKMLGTPEEAE 313
H LL E K+A+ + + ++A+ G E+ E
Sbjct: 1335 --HDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLE 1370
Score = 45.8 bits (107), Expect = 7e-05
Identities = 78/303 (25%), Positives = 123/303 (40%), Gaps = 55/303 (18%)
Query: 58 VVRALELLEQA-AVGPAPDSLQVSAQPAEQELRRLREENERLRRELRAGPQEERALLRQL 116
V+RA+E E+A A G ++ +S A +E + REE ER R LRA E ALL
Sbjct: 1481 VLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRA---ELEALLSS- 1536
Query: 117 KEVTDRQRDELRAHNRDLRQRGQETEALQEQLQRLLLVNAELRHKLAAMQTQLRAAQDRE 176
K+ + EL R Q + A +L+ L + + +L L+ +R+
Sbjct: 1537 KDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERD 1596
Query: 177 RE-RQQPGEAATPQ---------------AKERARGQAGR---PGHQHGQEPEWATAGAG 217
+ R + GE Q K+R A R G + + A+AG G
Sbjct: 1597 LQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQG 1656
Query: 218 APGNPEDPAEAAQQLGRPS--------EAGQCRFSREE-FEQILQERNELK---AKVFLL 265
EA +QL + E + R SREE F Q + LK A+V L
Sbjct: 1657 -------KEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRL 1709
Query: 266 KEEL---------AYFQRELLTDHRVPGLLLEAMKVAVRKQRKKIKAKMLGTPEEAESSE 316
+EEL A R+ + D G L K A+ +++++++ ++ EE E +
Sbjct: 1710 QEELAASDRARRQAQQDRDEMADEVANGNL---SKAAILEEKRQLEGRLGQLEEELEEEQ 1766
Query: 317 DEA 319
+
Sbjct: 1767 SNS 1769
Score = 39.7 bits (91), Expect = 0.005
Identities = 82/345 (23%), Positives = 124/345 (35%), Gaps = 47/345 (13%)
Query: 61 ALELLEQA-----AVGPAPDSLQVSAQPAEQELRRLREENERLRRELRAGPQEERALLRQ 115
A ELL++ A+G +++ A ++L ER REL Q +A L +
Sbjct: 1337 AQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGREL----QTAQAQLSE 1392
Query: 116 LKEVTDRQRDELRAHNRDLRQRGQETEALQEQLQRLLLVNAELRHKLAAMQTQL-RAAQD 174
+ + + L A R+ +E EAL ++L L +Q +L A D
Sbjct: 1393 WRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMD 1452
Query: 175 RERERQQPGEAATPQAK-----------------ERARGQAGRPGHQHGQEPEWATAGAG 217
E++RQ Q K ER R +A G+E E
Sbjct: 1453 LEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEA------EGRERE--ARALS 1504
Query: 218 APGNPEDPAEAAQQLGRPSEAGQCRFSREEFEQILQERNELKAKVFLLKEELAYFQRELL 277
E+ EA ++L R Q R R E E +L ++++ V L E +
Sbjct: 1505 LTRALEEEQEAREELER-----QNRALRAELEALLSSKDDVGKSVHEL-ERACRVAEQAA 1558
Query: 278 TDHRVPGLLLEAMKVAVR--KQRKKIKAKMLGTPEEAE-SSEDEAGP---WILLSDDKGD 331
D R LE A K R ++ + L T E + DEAG L +
Sbjct: 1559 NDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDA 1618
Query: 332 HPPPPESKIQSFFGLWYRGKAESSEDETSSPAPSKLGGEEEAQPQ 376
E + Q + R K E +E + S G+EEA Q
Sbjct: 1619 EVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQ 1663
Score = 33.1 bits (74), Expect = 0.46
Identities = 45/189 (23%), Positives = 75/189 (39%), Gaps = 21/189 (11%)
Query: 35 LGTELQDLARRFGPEAA----------AGLVPLVVRALELLEQAAVGPAPDSLQVSAQPA 84
L ++Q+L R G E A A L + +A E LEQ V + A
Sbjct: 1807 LERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLV--RRA 1864
Query: 85 EQELRRLR---EENERLRRELRAGPQEERALLRQLKEVTDRQRDELRAHNRDLRQRGQET 141
E+ L+ + EE R+ +LR ++ ++QLK + +E R+ +E
Sbjct: 1865 EKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQREL 1924
Query: 142 EALQEQLQRLLLVNAELRHKLAAMQTQLRAAQDRERERQQPGEAATPQAKERARGQAGRP 201
E + E + + LR++L R+ R + G A+ +A+E +P
Sbjct: 1925 EDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEE------AQP 1978
Query: 202 GHQHGQEPE 210
G EPE
Sbjct: 1979 GSGPSPEPE 1987
Score = 31.6 bits (70), Expect = 1.3
Identities = 34/147 (23%), Positives = 63/147 (42%), Gaps = 5/147 (3%)
Query: 39 LQDLARRFGPEAAAGLVPLV-VRALELLEQAAVGPAPDSLQVSAQPAEQELRRLREENER 97
L+D F +AA + + L L +A + D L+ + QEL +L+ +
Sbjct: 1021 LEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLR-KEEKGRQELEKLKRRLDG 1079
Query: 98 LRRELRAGPQEERALLRQLKEVTDRQRDELRAHNRDLRQRGQETEALQEQLQRLLLVNAE 157
EL+ E++ +L+ R+ +EL+A L + E A + L+ L A
Sbjct: 1080 ESSELQEQMVEQQQRAEELRAQLGRKEEELQA---ALARAEDEGGARAQLLKSLREAQAA 1136
Query: 158 LRHKLAAMQTQLRAAQDRERERQQPGE 184
L ++++ A E++R+ GE
Sbjct: 1137 LAEAQEDLESERVARTKAEKQRRDLGE 1163
>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
Length = 2036
Score = 47.8 bits (112), Expect = 2e-05
Identities = 74/278 (26%), Positives = 121/278 (43%), Gaps = 72/278 (25%)
Query: 67 QAAVGPAPDSLQ---VSAQPAEQELRRLREENERLRRELR-----AGPQEERALLRQLKE 118
QAA+ A + L+ V+ AE++ R L EE E LR EL Q+E R+ +E
Sbjct: 1175 QAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKRE-QE 1233
Query: 119 VTDRQR---DELRAHN---RDLRQR-GQETEALQEQLQ------------RLLLVN--AE 157
VT+ ++ +E R H ++LRQR GQ L EQL+ RL L +E
Sbjct: 1234 VTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSE 1293
Query: 158 LRHKLAAMQTQLRAAQDRERERQQPGEAATPQAKERARGQAGRPGHQHGQEPEWATAGAG 217
LR +L+++QT + + R R + + +A + R +
Sbjct: 1294 LRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERAR-------------------- 1333
Query: 218 APGNPEDPAEAAQQLGRPSEAGQCRFSREEFEQILQERNELKAKVFLLKEELAYFQRELL 277
AEAA++L R ++ E E + NE ++K L +EL+ + +L
Sbjct: 1334 --------AEAAEKLQR---------AQAELENVSGALNEAESKTIRLSKELSSTEAQL- 1375
Query: 278 TDHRVPGLLLE--AMKVAVRKQRKKIKAKMLGTPEEAE 313
H LL E K+A+ + + ++A+ G E+ E
Sbjct: 1376 --HDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLE 1411
Score = 45.8 bits (107), Expect = 7e-05
Identities = 78/303 (25%), Positives = 123/303 (40%), Gaps = 55/303 (18%)
Query: 58 VVRALELLEQA-AVGPAPDSLQVSAQPAEQELRRLREENERLRRELRAGPQEERALLRQL 116
V+RA+E E+A A G ++ +S A +E + REE ER R LRA E ALL
Sbjct: 1522 VLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRA---ELEALLSS- 1577
Query: 117 KEVTDRQRDELRAHNRDLRQRGQETEALQEQLQRLLLVNAELRHKLAAMQTQLRAAQDRE 176
K+ + EL R Q + A +L+ L + + +L L+ +R+
Sbjct: 1578 KDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERD 1637
Query: 177 RE-RQQPGEAATPQ---------------AKERARGQAGR---PGHQHGQEPEWATAGAG 217
+ R + GE Q K+R A R G + + A+AG G
Sbjct: 1638 LQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQG 1697
Query: 218 APGNPEDPAEAAQQLGRPS--------EAGQCRFSREE-FEQILQERNELK---AKVFLL 265
EA +QL + E + R SREE F Q + LK A+V L
Sbjct: 1698 -------KEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRL 1750
Query: 266 KEEL---------AYFQRELLTDHRVPGLLLEAMKVAVRKQRKKIKAKMLGTPEEAESSE 316
+EEL A R+ + D G L K A+ +++++++ ++ EE E +
Sbjct: 1751 QEELAASDRARRQAQQDRDEMADEVANGNL---SKAAILEEKRQLEGRLGQLEEELEEEQ 1807
Query: 317 DEA 319
+
Sbjct: 1808 SNS 1810
Score = 39.7 bits (91), Expect = 0.005
Identities = 82/345 (23%), Positives = 124/345 (35%), Gaps = 47/345 (13%)
Query: 61 ALELLEQA-----AVGPAPDSLQVSAQPAEQELRRLREENERLRRELRAGPQEERALLRQ 115
A ELL++ A+G +++ A ++L ER REL Q +A L +
Sbjct: 1378 AQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGREL----QTAQAQLSE 1433
Query: 116 LKEVTDRQRDELRAHNRDLRQRGQETEALQEQLQRLLLVNAELRHKLAAMQTQL-RAAQD 174
+ + + L A R+ +E EAL ++L L +Q +L A D
Sbjct: 1434 WRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMD 1493
Query: 175 RERERQQPGEAATPQAK-----------------ERARGQAGRPGHQHGQEPEWATAGAG 217
E++RQ Q K ER R +A G+E E
Sbjct: 1494 LEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEA------EGRERE--ARALS 1545
Query: 218 APGNPEDPAEAAQQLGRPSEAGQCRFSREEFEQILQERNELKAKVFLLKEELAYFQRELL 277
E+ EA ++L R Q R R E E +L ++++ V L E +
Sbjct: 1546 LTRALEEEQEAREELER-----QNRALRAELEALLSSKDDVGKSVHEL-ERACRVAEQAA 1599
Query: 278 TDHRVPGLLLEAMKVAVR--KQRKKIKAKMLGTPEEAE-SSEDEAGP---WILLSDDKGD 331
D R LE A K R ++ + L T E + DEAG L +
Sbjct: 1600 NDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDA 1659
Query: 332 HPPPPESKIQSFFGLWYRGKAESSEDETSSPAPSKLGGEEEAQPQ 376
E + Q + R K E +E + S G+EEA Q
Sbjct: 1660 EVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQ 1704
Score = 33.1 bits (74), Expect = 0.46
Identities = 45/189 (23%), Positives = 75/189 (39%), Gaps = 21/189 (11%)
Query: 35 LGTELQDLARRFGPEAA----------AGLVPLVVRALELLEQAAVGPAPDSLQVSAQPA 84
L ++Q+L R G E A A L + +A E LEQ V + A
Sbjct: 1848 LERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLV--RRA 1905
Query: 85 EQELRRLR---EENERLRRELRAGPQEERALLRQLKEVTDRQRDELRAHNRDLRQRGQET 141
E+ L+ + EE R+ +LR ++ ++QLK + +E R+ +E
Sbjct: 1906 EKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQREL 1965
Query: 142 EALQEQLQRLLLVNAELRHKLAAMQTQLRAAQDRERERQQPGEAATPQAKERARGQAGRP 201
E + E + + LR++L R+ R + G A+ +A+E +P
Sbjct: 1966 EDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEE------AQP 2019
Query: 202 GHQHGQEPE 210
G EPE
Sbjct: 2020 GSGPSPEPE 2028
Score = 31.6 bits (70), Expect = 1.3
Identities = 34/147 (23%), Positives = 63/147 (42%), Gaps = 5/147 (3%)
Query: 39 LQDLARRFGPEAAAGLVPLV-VRALELLEQAAVGPAPDSLQVSAQPAEQELRRLREENER 97
L+D F +AA + + L L +A + D L+ + QEL +L+ +
Sbjct: 1062 LEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLR-KEEKGRQELEKLKRRLDG 1120
Query: 98 LRRELRAGPQEERALLRQLKEVTDRQRDELRAHNRDLRQRGQETEALQEQLQRLLLVNAE 157
EL+ E++ +L+ R+ +EL+A L + E A + L+ L A
Sbjct: 1121 ESSELQEQMVEQQQRAEELRAQLGRKEEELQA---ALARAEDEGGARAQLLKSLREAQAA 1177
Query: 158 LRHKLAAMQTQLRAAQDRERERQQPGE 184
L ++++ A E++R+ GE
Sbjct: 1178 LAEAQEDLESERVARTKAEKQRRDLGE 1204
>gi|113425137 PREDICTED: similar to Golgin subfamily A member 8-like
protein 2 isoform 3 [Homo sapiens]
Length = 632
Score = 47.8 bits (112), Expect = 2e-05
Identities = 56/223 (25%), Positives = 99/223 (44%), Gaps = 31/223 (13%)
Query: 60 RALELLEQAAVGPAPDSLQVSAQPAEQELRRLREENERLRRELRAGPQEERALLRQLKEV 119
R+L L+ P P + A P+E EL+ LR+E ER+ EL++ + + + +
Sbjct: 282 RSLSKLKNQMAEPLPP--EPPAVPSEVELQHLRKELERVAGELQSQVKNN----QHISLL 335
Query: 120 TDRQRDELRAHNRDLRQRGQETEALQEQLQRLL---LVNAELRHK-LAAMQTQLRAAQDR 175
RQ + +R LR++ + + E+L++L V EL ++ + +Q + + + +
Sbjct: 336 NRRQEERIREQEERLRKQEERLQEQHEKLRQLAKPQSVFEELNNENKSTLQLEQQVKELQ 395
Query: 176 ERERQQPGEAATPQAKERAR--GQAGRPGHQHGQE---PEWATAGAGAPGNPEDPAEAAQ 230
E+ ++ EAA+ Q ++ PG HG E E A P PEDP
Sbjct: 396 EKLGEEHLEAASQQNQQLTAQLSLMALPGEGHGGEHLDSEGEEAPRPMPSVPEDP----- 450
Query: 231 QLGRPSEAGQCRFSREEFEQILQERNELKAKVFLLKEELAYFQ 273
+ R + F L+E+ +L V K+EL + Q
Sbjct: 451 ---------ESREAMSSFMDHLKEKADLSELV--KKQELRFIQ 482
Score = 34.3 bits (77), Expect = 0.21
Identities = 43/166 (25%), Positives = 72/166 (43%), Gaps = 29/166 (17%)
Query: 110 RALLRQLKEVTDRQRDELRAHNRDLRQRGQETEALQEQLQRLLLVNAELRHKLAAMQTQL 169
++L +Q K+V + +E +A+N +R + L+ Q+Q L++ EL L M+ L
Sbjct: 101 KSLKQQKKQVEHQLEEEKKANN----ERQKAERELEVQIQTLIIQKEELNTDLYHMERSL 156
Query: 170 RAAQDRERERQQPGEAATPQAKERARGQAGRPGHQHGQEPEWATAGAGAPGNPEDPAEAA 229
R ++ ++ A Q + +G E E A + A + A
Sbjct: 157 RYFEEESKDL-----AVRLQHSLQCKG-----------ELESALSAVIATEKKK-----A 195
Query: 230 QQLGRPSEAGQCRFSREEFEQILQERNELKAKVFLLKEELAYFQRE 275
QL S+A + E EQ LQ++ LKA++ LKE Q E
Sbjct: 196 NQLSSCSKA----HTEWELEQSLQDQALLKAQLTQLKESFQQLQLE 237
>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
Length = 2115
Score = 47.4 bits (111), Expect = 2e-05
Identities = 51/232 (21%), Positives = 99/232 (42%), Gaps = 16/232 (6%)
Query: 75 DSLQVSAQPA---EQELRRLREENERLRRELRAGPQEERALLRQLKEVTDRQRDELRAHN 131
DS Q AQ +++L L+EE E+ R+EL+ ++ + + RQ++EL +
Sbjct: 819 DSQQEEAQYGAMFQEQLMTLKEECEKARQELQEAKEKVAGIESHSELQISRQQNELAELH 878
Query: 132 RDLRQRGQETEALQEQLQRLLLVNAELRHKLAAMQTQLRAAQDRERERQQPGEAATPQAK 191
+L + Q+ + + + Q+L + L+ K+AA ++ + R+ + E A
Sbjct: 879 ANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLETLVRKAGEQQETA----- 933
Query: 192 ERARGQAGRPGHQHGQEPEWATAGAGAPGNPEDPA-----EAAQQLGRPSEAGQCRFSRE 246
+R P ++PEW G A A+Q+G E +
Sbjct: 934 --SRELVKEPARAGDRQPEWLEEQQGRQFCSTQAALQAMEREAEQMGNELERLRAALMES 991
Query: 247 EFEQILQERNELKAKVFLLKEELAYFQRELLTDHRVPGLLLEAMKVAVRKQR 298
+ +Q +ER + + +V L +E Q +L + L ++ A+ +QR
Sbjct: 992 QGQQ-QEERGQQEREVARLTQERGRAQADLALEKAARAELEMRLQNALNEQR 1042
Score = 45.4 bits (106), Expect = 9e-05
Identities = 61/247 (24%), Positives = 108/247 (43%), Gaps = 26/247 (10%)
Query: 77 LQVSAQPAEQELRRLREENERLRRELRAGPQEERALLRQLKEVTDRQRDELRAHNRDLRQ 136
L + Q EQ + LR + E+L L+ Q QLKEV ++Q + H + L
Sbjct: 535 LAQTLQQQEQASQGLRHQVEQLSSSLKQKEQ-------QLKEVAEKQEATRQDHAQQLAT 587
Query: 137 RGQETEA-LQEQ---LQRLLLVNAELRHKLAAMQTQLRAAQDRERERQQPGEAATPQAKE 192
+E EA L+E+ L++L + E KL +Q QL+ A E + + + QA +
Sbjct: 588 AAEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQVAN----EARDSAQTSVTQA-Q 642
Query: 193 RARGQAGRPGHQHGQEPEWATAGAGAPGNPEDPAEAAQ-QLGRPSEAGQCRFSREEFEQI 251
R + + R E A E A+ A+ +L SE + E E++
Sbjct: 643 REKAELSRK-----VEELQACVETARQEQHEAQAQVAELELQLRSEQQKAT----EKERV 693
Query: 252 LQERNELKAKVFLLKEELAYFQRELLTDHRVPGLLLEAMKVAVRKQRKKIKAKMLGTPEE 311
QE+++L+ ++ LKE L + L + R LE + + + + + ++ + E
Sbjct: 694 AQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHKRE 753
Query: 312 AESSEDE 318
+ E+E
Sbjct: 754 RKELEEE 760
Score = 33.9 bits (76), Expect = 0.27
Identities = 63/249 (25%), Positives = 101/249 (40%), Gaps = 38/249 (15%)
Query: 85 EQELRRLREENERLRRELRAGPQEERALLRQLKEVTDRQRDELRAHNRDLRQRGQETEAL 144
E +R+ E+ E REL P RA RQ + + ++Q + + L+ +E E +
Sbjct: 920 ETLVRKAGEQQETASRELVKEPA--RAGDRQPEWLEEQQGRQFCSTQAALQAMEREAEQM 977
Query: 145 QEQLQRLLLVNAELRHKLAAMQTQLRAAQDRERER--QQPGEAATPQAKERARGQAGRPG 202
+L+RL E + Q + R Q+RE R Q+ G A A E+A
Sbjct: 978 GNELERLRAALMESQ----GQQQEERGQQEREVARLTQERGRAQADLALEKAARAELEMR 1033
Query: 203 HQHG---QEPEWATAGAGAPGNPEDPAEAAQQLG--RPSEAGQCRFSREEFEQILQERNE 257
Q+ Q E+AT + Q+L R EA Q ++E E
Sbjct: 1034 LQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEAAQ-----------IKELEE 1082
Query: 258 LKAKVFLLKEELAYFQRELLTDH----------RVPGLLLEAMKVAVRKQRKKIKAKMLG 307
L+ V LKE+LA ++E + G LEA++ V K ++ + +
Sbjct: 1083 LRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQ-- 1140
Query: 308 TPEEAESSE 316
E+A+S E
Sbjct: 1141 --EQADSLE 1147
Score = 33.9 bits (76), Expect = 0.27
Identities = 57/246 (23%), Positives = 103/246 (41%), Gaps = 20/246 (8%)
Query: 35 LGTELQDLARRFGPEAAAGLVPLVVRALELLEQAAVGPAPDSLQVSAQPAEQELRRLREE 94
L EL ++ E AA R E+ +A L+V E ++ EE
Sbjct: 1465 LEVELDQAREKYVQELAAVRADAETRLAEVQREAQ--STARELEVMTAKYEGAKVKVLEE 1522
Query: 95 NERLRRELRAGPQEERALLRQLKEVTDRQRDELRAHNRDLRQRGQETEALQEQLQRLLLV 154
+R + +E + L Q++++ QR++ + ++ +A + Q Q+L V
Sbjct: 1523 RQRFQ-------EERQKLTAQVEQLEVFQREQTKQVEELSKKLADSDQASKVQQQKLKAV 1575
Query: 155 NA---ELRHKLAAMQTQLRAAQDRERERQQPGEAATPQ-AKERARGQAGRPGHQHGQEPE 210
A E + + +Q QL Q + +++Q E Q K + A + +Q QE +
Sbjct: 1576 QAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQE-Q 1634
Query: 211 WATAGAGAPGNPEDPAEAAQQLGRPSEAGQCRFSREEFEQILQERNELKAKVFLLKEELA 270
+ N E AE A++LG E Q +E EQ + L A+V L+ ++A
Sbjct: 1635 LRSLEQLQKENKELRAE-AERLGH--ELQQAGLKTKEAEQTCR---HLTAQVRSLEAQVA 1688
Query: 271 YFQREL 276
+ ++L
Sbjct: 1689 HADQQL 1694
Score = 32.3 bits (72), Expect = 0.78
Identities = 55/277 (19%), Positives = 104/277 (37%), Gaps = 29/277 (10%)
Query: 71 GPAPDSLQVSAQPAEQELRRLREENERLRREL---RAGPQEERALLRQLKEVTDRQRDEL 127
GP ++L+ EQ+ ++ +E+ + L R L RA E + L L+ + + EL
Sbjct: 1119 GPKLEALRAEVSKLEQQCQKQQEQADSLERSLEAERASRAERDSALETLQGQLEEKAQEL 1178
Query: 128 RAHNRDLRQRGQETEALQEQLQ-----------------------RLLLVNAELRHKLAA 164
L +E A + ++Q L+ + E +
Sbjct: 1179 GHSQSALASAQRELAAFRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILN 1238
Query: 165 MQTQLRAAQDRERERQQPGEAATPQ-AKERARGQAGRPGHQHGQEPEWATAGAGAPGNPE 223
Q + + +E +R E+ Q +ER R + E ++A +
Sbjct: 1239 RQVLEKEGESKELKRLVMAESEKSQKLEERLRLLQAETASNSARAAERSSALREEVQSLR 1298
Query: 224 DPAEAAQQLGRPSEAGQCRFSREEFEQILQERNELKAKVFLLKEELAYFQRELLTDHRVP 283
+ AE Q++ + + E E++ QE + K F ++ L+ Q E + +
Sbjct: 1299 EEAE-KQRVASENLRQELTSQAERAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALV 1357
Query: 284 GLLLEAMKVAVRKQRKKIKAKMLGTPEEAESSEDEAG 320
LL A + + Q ++ A+ EE E S+ AG
Sbjct: 1358 SELLPAKHLCQQLQAEQAAAEKRHR-EELEQSKQAAG 1393
Score = 30.0 bits (66), Expect = 3.9
Identities = 37/146 (25%), Positives = 62/146 (42%), Gaps = 23/146 (15%)
Query: 66 EQAAVGPAPDSLQVSAQPAEQELRRLREENERLRREL---RAGPQEERALLRQLKEVTDR 122
E+ A + Q + E R L E+++R R+EL RAG + A L+QL E
Sbjct: 721 EKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQLGEAHQA 780
Query: 123 QRDELRAHNRDLRQRGQETEALQEQLQRLLLVNAELRHKL-----------AAMQTQLRA 171
+ + LR R+L + + + ++L+ A R + A Q QL
Sbjct: 781 ETEVLR---RELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMT 837
Query: 172 AQDR-ERERQQPGEAATPQAKERARG 196
++ E+ RQ+ +AKE+ G
Sbjct: 838 LKEECEKARQE-----LQEAKEKVAG 858
Score = 28.9 bits (63), Expect = 8.6
Identities = 31/128 (24%), Positives = 52/128 (40%), Gaps = 8/128 (6%)
Query: 57 LVVRALELLEQAAVGPAPDSLQVSAQPAEQELRRLREENERLRRELRAGPQEERALLRQL 116
L +R E L+Q L+ ++++ +L EEN L +LR + L L
Sbjct: 288 LTMRLHETLKQC------QDLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDAL 341
Query: 117 KEVTDRQRDELRAHNRDLRQRGQETEALQEQLQRLLLVNAELRHKLAAMQTQLRAAQDRE 176
E+T+ + Q +E A + + L N L+ KL+ ++ L QD
Sbjct: 342 NELTEEHSKATQEWLEKQAQLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQD-- 399
Query: 177 RERQQPGE 184
Q+ GE
Sbjct: 400 NPPQEKGE 407
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 47.4 bits (111), Expect = 2e-05
Identities = 80/321 (24%), Positives = 139/321 (43%), Gaps = 48/321 (14%)
Query: 21 SASAAELVYHLAGALGTELQDLARRFGPEAAAGLVPLVVRALELLEQAAVGPAPDSLQVS 80
+A AEL L G + + +D R + A L R L E+ A + +Q S
Sbjct: 1938 AAGKAELELEL-GRIRSNAEDTLRS---KEQAELEAARQRQLAAEEERRRREAEERVQKS 1993
Query: 81 AQPAEQELRRLR---EENERLR------RELRAGPQEERALLRQLKEVTDRQR--DELRA 129
E+ R+ + EE ERL+ R LR ++E A QL + ++R E +A
Sbjct: 1994 LAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKA 2053
Query: 130 HNRDLRQRGQETEALQEQLQRLLLVNAELRHKL------------AAMQTQLRAAQDRER 177
H ++Q+ QE LQ+ LQ+ V +LR + A +Q + AAQ R +
Sbjct: 2054 HAFAVQQKEQE---LQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQ 2110
Query: 178 --ERQQPGEAATPQAKERARGQAGRPGHQHGQEPEWATAGAGAPGNPEDPAEAAQQLGRP 235
E ++ ++A QA+ RA+ QA + E E A A+A Q R
Sbjct: 2111 VEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARR-----------AQAEQAALRQ 2159
Query: 236 SEAGQCRFSREE--FEQILQERNELKAKVFLLKEELAYFQREL-LTDHRVPGLLLEAMKV 292
+A + + EQ L+++ +++ ++ L+ +L + L D + L EA +
Sbjct: 2160 KQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEA 2219
Query: 293 AVRKQRKKIKAKMLGTPEEAE 313
A +QR +++ ++ + E
Sbjct: 2220 A--RQRSQVEEELFSVRVQME 2238
Score = 46.2 bits (108), Expect = 5e-05
Identities = 83/336 (24%), Positives = 129/336 (38%), Gaps = 76/336 (22%)
Query: 54 LVPLVVRALELLEQAAVGPAPDSLQVSAQPAEQELRRLREENERLRRELRAGPQEER--- 110
+V L + A E A G +L+ A+ AE + R+ +EE ERLRR+++ Q +R
Sbjct: 1456 VVRLQLEATERQRGGAEGEL-QALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAE 1514
Query: 111 -ALLRQLKEVTDRQRDELRA-------------HNRDLRQ----RGQETEALQEQLQRLL 152
L ++K + R++ RA R LRQ R ++ + E QR
Sbjct: 1515 VELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQR-- 1572
Query: 153 LVNAELRHKLAAMQ-----------------TQLRAAQDRERERQQPGEAATPQAKE--- 192
AEL+ K A+ QLR +R ++Q E A +A+
Sbjct: 1573 SAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELE 1632
Query: 193 ----------RARGQAGRPGHQHG-------QEPEWATAGAGAPGNPEDPAEAAQQLGRP 235
R R QA Q ++ E A A G E+ A ++L
Sbjct: 1633 RWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQ 1692
Query: 236 SEAGQCRFSREEFEQILQERNEL----------KAKVFLLKEELAYFQRE--LLTDHRVP 283
Q + + +Q L EL + + LL+EELA QRE T R
Sbjct: 1693 ELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQE 1752
Query: 284 GLLLEAMKVAVRKQRKKIKAKMLGTPEEAESSEDEA 319
LEA VR + + + A EE+ S+ +++
Sbjct: 1753 ---LEAELAKVRAEMEVLLASKARAEEESRSTSEKS 1785
Score = 45.4 bits (106), Expect = 9e-05
Identities = 61/223 (27%), Positives = 94/223 (42%), Gaps = 31/223 (13%)
Query: 81 AQPAEQELRRLREENERLRRELRAGPQEERALLRQLKEVTDRQRDELRAHNRDLRQRGQE 140
AQ +E +R +++ E+ R+ L A +E R + +E R+++EL+ + QR Q+
Sbjct: 2527 AQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQ---QRRQQ 2583
Query: 141 TEALQEQLQRLLLVNAELRHKLAAMQTQLRAAQDRERERQQPGEAATPQAKERARGQAGR 200
E L E+ QRL R +L ++ Q RAA E AAT K G+
Sbjct: 2584 EELLAEENQRL-------REQLQLLEEQHRAALAHSEEVTASQVAAT---KTLPNGRDAL 2633
Query: 201 PGHQHGQEPEWATAGAGAPGNPED-------PAEAAQQLGRPSEAGQCRFSREEFEQILQ 253
G EPE + G + + AE Q+L + RE+ LQ
Sbjct: 2634 DGPAAEAEPEHSFDGLRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQ 2693
Query: 254 ERNELKAKVFLLKEE----LAYFQRELLTDHRVPG---LLLEA 289
R+ + + E A QR+LL+ PG +LLEA
Sbjct: 2694 GRSSIAGLLLKATNEKLSVYAALQRQLLS----PGTALILLEA 2732
Score = 45.1 bits (105), Expect = 1e-04
Identities = 55/190 (28%), Positives = 89/190 (46%), Gaps = 15/190 (7%)
Query: 86 QELRRLREENERLRRELRAGPQEERALLRQLKEVTDRQRDELRAHNRDLRQRGQETEALQ 145
+ LRR+ EE ERL + RA EER L +++ ++QR AH + Q +E + LQ
Sbjct: 1339 ETLRRMEEE-ERLAEQQRA---EERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQ 1394
Query: 146 EQLQRLLLVNAELRHKLAAM--QTQLRAAQDRERERQQPGEAATPQAKERARGQAGRPGH 203
+++Q + +R + AA+ Q Q R+ Q+ ++ +Q EA QAK R A R
Sbjct: 1395 QRMQEEV-----VRREEAAVDAQQQKRSIQEELQQLRQSSEAEI-QAKARQAEAAERSRL 1448
Query: 204 QHGQEPEWATAGAGAPGNPEDPAEAAQQL--GRPSEA-GQCRFSREEFEQILQERNELKA 260
+ +E A AE Q R EA Q R ++EE E++ ++ +
Sbjct: 1449 RIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQ 1508
Query: 261 KVFLLKEELA 270
+ + ELA
Sbjct: 1509 RKRQAEVELA 1518
Score = 44.3 bits (103), Expect = 2e-04
Identities = 58/223 (26%), Positives = 98/223 (43%), Gaps = 26/223 (11%)
Query: 57 LVVRALELLEQAAVGPAPDSLQVSAQPAEQELRRLREENERLRRELRAGPQEERALLRQL 116
L ++A E+ +Q ++ A Q + AE+E RR + E+ R+ R ++E RQL
Sbjct: 1644 LRLQAEEVAQQKSLAQAEAEKQ--KEEAEREARRRGKAEEQAVRQ-RELAEQELEKQRQL 1700
Query: 117 KEVTDRQR----DELRAHNRDLRQRGQETEALQEQLQRLLLVNA-------ELRHKLAAM 165
E T +QR EL + Q Q+ + L+E+L RL A EL +LA +
Sbjct: 1701 AEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKV 1760
Query: 166 QTQLRAAQDRERERQQPGEAATPQAKERARGQAGRPGHQHGQEPEWATAGAGAPGNPEDP 225
+ ++ + ++ + + ++K+R +AGR E A A E+
Sbjct: 1761 RAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGR-------FRELAEEAARLRALAEE- 1812
Query: 226 AEAAQQLGRPSEAGQCRFSREEFEQILQERNELKAKVFLLKEE 268
A+ +QL A Q R E E++L E+ + LK E
Sbjct: 1813 AKRQRQLAEEDAARQ----RAEAERVLAEKLAAIGEATRLKTE 1851
Score = 43.5 bits (101), Expect = 3e-04
Identities = 59/255 (23%), Positives = 103/255 (40%), Gaps = 35/255 (13%)
Query: 75 DSLQVSAQPAEQELRRLREENERLRRELRAGPQEERALLRQLKEVTDRQRDELRAHNRDL 134
+ LQ Q +E E++ + E R R +EE ++R E T+RQR + L
Sbjct: 1420 EELQQLRQSSEAEIQAKARQAEAAERS-RLRIEEEIRVVRLQLEATERQRGGAEGELQAL 1478
Query: 135 RQRGQETEALQEQLQRLLLVNAELRHKLAAMQTQLRAAQDRERERQQPGEAATPQAKERA 194
R R +E EA + Q Q A + + + + +R+RQ E A ++ +A
Sbjct: 1479 RARAEEAEAQKRQAQE------------EAERLRRQVQDESQRKRQAEVELA---SRVKA 1523
Query: 195 RGQAGRPGHQHGQEPEWATAGAGAPGNPEDPAEAAQQLGRPSEAGQCRFSREEFEQILQE 254
+A R + Q E AE A++ R +E + R + E +
Sbjct: 1524 EAEAAREKQRALQALEELRL----------QAEEAERRLRQAEVERARQVQVALETAQRS 1573
Query: 255 RN-ELKAKVFLLKEELAYFQRELLTDHRVPGLLLEAMKVAVRKQRKKIKAKMLGTPEEAE 313
EL++K E+ A +R L +H L E + ++Q + +A+ E
Sbjct: 1574 AEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAR--------E 1625
Query: 314 SSEDEAGPWILLSDD 328
+E E W L +++
Sbjct: 1626 EAERELERWQLKANE 1640
Score = 43.5 bits (101), Expect = 3e-04
Identities = 55/251 (21%), Positives = 95/251 (37%), Gaps = 21/251 (8%)
Query: 84 AEQELRRLREENERLRRELRAGPQEERALLRQLKEVTDRQRDELRAHNRDLRQRGQETEA 143
A QE RL+ E E L+++ ++ R L +++ + +E + R L Q
Sbjct: 2318 AVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLE 2377
Query: 144 LQEQLQRLLLVNAELRHKLAAMQTQLRAAQDRERERQQPGEAA-----TPQAKERARGQA 198
+ + +RL L AE+ + Q RA +D +R R+Q E T A +
Sbjct: 2378 MSAEAERLKLRVAEM------SRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLV 2431
Query: 199 GRPGHQHGQEPEWATAGAGAPGNPEDPAEAAQQLGRPSEAGQCRFSREEFEQILQERNEL 258
Q Q A A E E QQ + + + EQ+LQE L
Sbjct: 2432 QTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQAL 2491
Query: 259 KAKVFLLKEELAYFQR----------ELLTDHRVPGLLLEAMKVAVRKQRKKIKAKMLGT 308
+ K+ L +R +L D L + ++Q ++ + +++ +
Sbjct: 2492 QQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVAS 2551
Query: 309 PEEAESSEDEA 319
EEA + EA
Sbjct: 2552 MEEARRRQHEA 2562
Score = 39.3 bits (90), Expect = 0.006
Identities = 82/337 (24%), Positives = 124/337 (36%), Gaps = 34/337 (10%)
Query: 49 EAAAGLVPLVVRALELLEQAA-VGPAPDSLQVSAQPAEQELRRLREENERLRRELRAGPQ 107
EA AG R EL E+AA + + + Q AE++ R R E ER+ E A
Sbjct: 1790 EAEAG------RFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIG 1843
Query: 108 EERALLRQLKEVTDRQRDELRAHNRDLRQRGQETEALQEQLQRLLLVNAELRHK--LAAM 165
E +LK + E A N LR+ ++ E QR L +HK +
Sbjct: 1844 EAT----RLKTEAEIALKEKEAENERLRRLAED-----EAFQRRRLEEQAAQHKADIEER 1894
Query: 166 QTQLRAAQDRERERQQPGEAATPQAKERARGQAGRPGHQHGQEPEWATAGAG-------- 217
QLR A D E ERQ+ + R R Q E A AG
Sbjct: 1895 LAQLRKASDSELERQK----GLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGR 1950
Query: 218 APGNPEDPAEAAQQLGRPSEAGQCRFSREEFEQILQERNELKAKVFLLKEELAYFQRELL 277
N ED + +Q EA + R E E+ +E E K +EE A ++ L
Sbjct: 1951 IRSNAEDTLRSKEQ--AELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAAL 2008
Query: 278 TD-HRVPGLLLEAMKVAVRKQRKKIKAKMLGTPEEAESSEDEAGPWILLSDDKGDHPPPP 336
+ R+ + EA ++ R +++ + L + + E K
Sbjct: 2009 EEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQT 2068
Query: 337 ESKIQSFFGLWYRGKAESSEDETSSPAPSKLGGEEEA 373
+ QS RG+AE++ +++ E EA
Sbjct: 2069 LQQEQSVLD-QLRGEAEAARRAAEEAEEARVQAEREA 2104
Score = 35.8 bits (81), Expect = 0.071
Identities = 36/142 (25%), Positives = 63/142 (44%), Gaps = 6/142 (4%)
Query: 57 LVVRALELLEQAAVGPAPDSLQVSAQPAEQELRRLREENERLRRELRAGPQEERALLRQL 116
L+ + EL ++ A D Q++ Q AE+ R +R+L + ER LR
Sbjct: 2331 LLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLR-- 2388
Query: 117 KEVTDRQRDELRAHNRDLRQRGQETEALQEQLQRLLLVNAELRHKLAAMQTQLRAAQDRE 176
V + R + RA D ++ ++ E + E+L R L E + ++ Q R D +
Sbjct: 2389 --VAEMSRAQARA-EEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQ-RQQSDHD 2444
Query: 177 RERQQPGEAATPQAKERARGQA 198
ER + A + KE+ + +A
Sbjct: 2445 AERLREAIAELEREKEKLQQEA 2466
Score = 35.0 bits (79), Expect = 0.12
Identities = 33/119 (27%), Positives = 50/119 (42%), Gaps = 14/119 (11%)
Query: 75 DSLQVSAQPAEQELRRLREENERLRRELRAGPQEERALLRQLKEVTDRQ----------R 124
+ LQ Q Q+ L EEN+RLR +L+ ++ RA L +EVT Q R
Sbjct: 2571 EELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGR 2630
Query: 125 DELRAHNRDLRQR----GQETEALQEQLQRLLLVNAELRHKLAAMQTQLRAAQDRERER 179
D L + G + ++LQ +++AE +LA T + RE R
Sbjct: 2631 DALDGPAAEAEPEHSFDGLRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVR 2689
Score = 33.9 bits (76), Expect = 0.27
Identities = 47/207 (22%), Positives = 90/207 (43%), Gaps = 23/207 (11%)
Query: 84 AEQELRRLREENERLRRELRAGP--QEERALLRQLKEVTDRQRDELRAHNRD-LRQRGQE 140
AE++ +R R++ E + +L +E+ L Q E+ +Q D R+ + + +E
Sbjct: 2399 AEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELERE 2458
Query: 141 TEALQEQLQRLLLVNAELR--------HKLAAMQTQLRAAQDR--ERERQQPGEAATPQ- 189
E LQ++ + L L + E++ + A+Q + +D +RER E A +
Sbjct: 2459 KEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQ 2518
Query: 190 -------AKERARGQAGRPGHQHGQEPEWATAGAGAPGNPEDPAEAAQQLGRPSEAGQCR 242
++ R + R Q QE + A + AE + + E Q
Sbjct: 2519 LFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVR-RKQEELQQLE 2577
Query: 243 FSREEFEQILQERNE-LKAKVFLLKEE 268
R + E++L E N+ L+ ++ LL+E+
Sbjct: 2578 QQRRQQEELLAEENQRLREQLQLLEEQ 2604
Score = 33.5 bits (75), Expect = 0.35
Identities = 63/248 (25%), Positives = 98/248 (39%), Gaps = 33/248 (13%)
Query: 59 VRALELLEQAAVGPAPDSLQVSAQPAEQELRRLREENERLRRELRAGPQEERALLRQ--- 115
V E L+Q+A A Q AQ A ++LR+ E E RR Q E+A LRQ
Sbjct: 2111 VEEAERLKQSAEEQAQARAQ--AQAAAEKLRK-EAEQEAARRA-----QAEQAALRQKQA 2162
Query: 116 ----------LKEVTDRQRDELRAHNRDLRQRGQETE----ALQEQLQRLLLVNAELRHK 161
E T RQ+ ++ LR + +ET+ L E+LQRL E +
Sbjct: 2163 ADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQ 2222
Query: 162 LAAMQTQL---RAAQDRERERQQPGEAATPQAKERARGQAGRPGHQHGQEPEWATAGAGA 218
+ ++ +L R + + + EA R + R + ++ + A
Sbjct: 2223 RSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAAR 2282
Query: 219 PGNPEDPAEAAQQLGRPSEAGQCRFSR---EEFEQILQERNELKAKVFLLKE--ELAYFQ 273
A +QL A Q + +E Q +QE LKA+ LL++ ELA Q
Sbjct: 2283 LSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQ 2342
Query: 274 RELLTDHR 281
L + +
Sbjct: 2343 ARRLQEDK 2350
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 47.4 bits (111), Expect = 2e-05
Identities = 80/321 (24%), Positives = 139/321 (43%), Gaps = 48/321 (14%)
Query: 21 SASAAELVYHLAGALGTELQDLARRFGPEAAAGLVPLVVRALELLEQAAVGPAPDSLQVS 80
+A AEL L G + + +D R + A L R L E+ A + +Q S
Sbjct: 1942 AAGKAELELEL-GRIRSNAEDTLRS---KEQAELEAARQRQLAAEEERRRREAEERVQKS 1997
Query: 81 AQPAEQELRRLR---EENERLR------RELRAGPQEERALLRQLKEVTDRQR--DELRA 129
E+ R+ + EE ERL+ R LR ++E A QL + ++R E +A
Sbjct: 1998 LAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKA 2057
Query: 130 HNRDLRQRGQETEALQEQLQRLLLVNAELRHKL------------AAMQTQLRAAQDRER 177
H ++Q+ QE LQ+ LQ+ V +LR + A +Q + AAQ R +
Sbjct: 2058 HAFAVQQKEQE---LQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQ 2114
Query: 178 --ERQQPGEAATPQAKERARGQAGRPGHQHGQEPEWATAGAGAPGNPEDPAEAAQQLGRP 235
E ++ ++A QA+ RA+ QA + E E A A+A Q R
Sbjct: 2115 VEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARR-----------AQAEQAALRQ 2163
Query: 236 SEAGQCRFSREE--FEQILQERNELKAKVFLLKEELAYFQREL-LTDHRVPGLLLEAMKV 292
+A + + EQ L+++ +++ ++ L+ +L + L D + L EA +
Sbjct: 2164 KQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEA 2223
Query: 293 AVRKQRKKIKAKMLGTPEEAE 313
A +QR +++ ++ + E
Sbjct: 2224 A--RQRSQVEEELFSVRVQME 2242
Score = 46.2 bits (108), Expect = 5e-05
Identities = 83/336 (24%), Positives = 129/336 (38%), Gaps = 76/336 (22%)
Query: 54 LVPLVVRALELLEQAAVGPAPDSLQVSAQPAEQELRRLREENERLRRELRAGPQEER--- 110
+V L + A E A G +L+ A+ AE + R+ +EE ERLRR+++ Q +R
Sbjct: 1460 VVRLQLEATERQRGGAEGEL-QALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAE 1518
Query: 111 -ALLRQLKEVTDRQRDELRA-------------HNRDLRQ----RGQETEALQEQLQRLL 152
L ++K + R++ RA R LRQ R ++ + E QR
Sbjct: 1519 VELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQR-- 1576
Query: 153 LVNAELRHKLAAMQ-----------------TQLRAAQDRERERQQPGEAATPQAKE--- 192
AEL+ K A+ QLR +R ++Q E A +A+
Sbjct: 1577 SAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELE 1636
Query: 193 ----------RARGQAGRPGHQHG-------QEPEWATAGAGAPGNPEDPAEAAQQLGRP 235
R R QA Q ++ E A A G E+ A ++L
Sbjct: 1637 RWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQ 1696
Query: 236 SEAGQCRFSREEFEQILQERNEL----------KAKVFLLKEELAYFQRE--LLTDHRVP 283
Q + + +Q L EL + + LL+EELA QRE T R
Sbjct: 1697 ELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQE 1756
Query: 284 GLLLEAMKVAVRKQRKKIKAKMLGTPEEAESSEDEA 319
LEA VR + + + A EE+ S+ +++
Sbjct: 1757 ---LEAELAKVRAEMEVLLASKARAEEESRSTSEKS 1789
Score = 45.4 bits (106), Expect = 9e-05
Identities = 61/223 (27%), Positives = 94/223 (42%), Gaps = 31/223 (13%)
Query: 81 AQPAEQELRRLREENERLRRELRAGPQEERALLRQLKEVTDRQRDELRAHNRDLRQRGQE 140
AQ +E +R +++ E+ R+ L A +E R + +E R+++EL+ + QR Q+
Sbjct: 2531 AQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQ---QRRQQ 2587
Query: 141 TEALQEQLQRLLLVNAELRHKLAAMQTQLRAAQDRERERQQPGEAATPQAKERARGQAGR 200
E L E+ QRL R +L ++ Q RAA E AAT K G+
Sbjct: 2588 EELLAEENQRL-------REQLQLLEEQHRAALAHSEEVTASQVAAT---KTLPNGRDAL 2637
Query: 201 PGHQHGQEPEWATAGAGAPGNPED-------PAEAAQQLGRPSEAGQCRFSREEFEQILQ 253
G EPE + G + + AE Q+L + RE+ LQ
Sbjct: 2638 DGPAAEAEPEHSFDGLRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQ 2697
Query: 254 ERNELKAKVFLLKEE----LAYFQRELLTDHRVPG---LLLEA 289
R+ + + E A QR+LL+ PG +LLEA
Sbjct: 2698 GRSSIAGLLLKATNEKLSVYAALQRQLLS----PGTALILLEA 2736
Score = 45.1 bits (105), Expect = 1e-04
Identities = 55/190 (28%), Positives = 89/190 (46%), Gaps = 15/190 (7%)
Query: 86 QELRRLREENERLRRELRAGPQEERALLRQLKEVTDRQRDELRAHNRDLRQRGQETEALQ 145
+ LRR+ EE ERL + RA EER L +++ ++QR AH + Q +E + LQ
Sbjct: 1343 ETLRRMEEE-ERLAEQQRA---EERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQ 1398
Query: 146 EQLQRLLLVNAELRHKLAAM--QTQLRAAQDRERERQQPGEAATPQAKERARGQAGRPGH 203
+++Q + +R + AA+ Q Q R+ Q+ ++ +Q EA QAK R A R
Sbjct: 1399 QRMQEEV-----VRREEAAVDAQQQKRSIQEELQQLRQSSEAEI-QAKARQAEAAERSRL 1452
Query: 204 QHGQEPEWATAGAGAPGNPEDPAEAAQQL--GRPSEA-GQCRFSREEFEQILQERNELKA 260
+ +E A AE Q R EA Q R ++EE E++ ++ +
Sbjct: 1453 RIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQ 1512
Query: 261 KVFLLKEELA 270
+ + ELA
Sbjct: 1513 RKRQAEVELA 1522
Score = 44.3 bits (103), Expect = 2e-04
Identities = 58/223 (26%), Positives = 98/223 (43%), Gaps = 26/223 (11%)
Query: 57 LVVRALELLEQAAVGPAPDSLQVSAQPAEQELRRLREENERLRRELRAGPQEERALLRQL 116
L ++A E+ +Q ++ A Q + AE+E RR + E+ R+ R ++E RQL
Sbjct: 1648 LRLQAEEVAQQKSLAQAEAEKQ--KEEAEREARRRGKAEEQAVRQ-RELAEQELEKQRQL 1704
Query: 117 KEVTDRQR----DELRAHNRDLRQRGQETEALQEQLQRLLLVNA-------ELRHKLAAM 165
E T +QR EL + Q Q+ + L+E+L RL A EL +LA +
Sbjct: 1705 AEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKV 1764
Query: 166 QTQLRAAQDRERERQQPGEAATPQAKERARGQAGRPGHQHGQEPEWATAGAGAPGNPEDP 225
+ ++ + ++ + + ++K+R +AGR E A A E+
Sbjct: 1765 RAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGR-------FRELAEEAARLRALAEE- 1816
Query: 226 AEAAQQLGRPSEAGQCRFSREEFEQILQERNELKAKVFLLKEE 268
A+ +QL A Q R E E++L E+ + LK E
Sbjct: 1817 AKRQRQLAEEDAARQ----RAEAERVLAEKLAAIGEATRLKTE 1855
Score = 43.5 bits (101), Expect = 3e-04
Identities = 59/255 (23%), Positives = 103/255 (40%), Gaps = 35/255 (13%)
Query: 75 DSLQVSAQPAEQELRRLREENERLRRELRAGPQEERALLRQLKEVTDRQRDELRAHNRDL 134
+ LQ Q +E E++ + E R R +EE ++R E T+RQR + L
Sbjct: 1424 EELQQLRQSSEAEIQAKARQAEAAERS-RLRIEEEIRVVRLQLEATERQRGGAEGELQAL 1482
Query: 135 RQRGQETEALQEQLQRLLLVNAELRHKLAAMQTQLRAAQDRERERQQPGEAATPQAKERA 194
R R +E EA + Q Q A + + + + +R+RQ E A ++ +A
Sbjct: 1483 RARAEEAEAQKRQAQE------------EAERLRRQVQDESQRKRQAEVELA---SRVKA 1527
Query: 195 RGQAGRPGHQHGQEPEWATAGAGAPGNPEDPAEAAQQLGRPSEAGQCRFSREEFEQILQE 254
+A R + Q E AE A++ R +E + R + E +
Sbjct: 1528 EAEAAREKQRALQALEELRL----------QAEEAERRLRQAEVERARQVQVALETAQRS 1577
Query: 255 RN-ELKAKVFLLKEELAYFQRELLTDHRVPGLLLEAMKVAVRKQRKKIKAKMLGTPEEAE 313
EL++K E+ A +R L +H L E + ++Q + +A+ E
Sbjct: 1578 AEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAR--------E 1629
Query: 314 SSEDEAGPWILLSDD 328
+E E W L +++
Sbjct: 1630 EAERELERWQLKANE 1644
Score = 43.5 bits (101), Expect = 3e-04
Identities = 55/251 (21%), Positives = 95/251 (37%), Gaps = 21/251 (8%)
Query: 84 AEQELRRLREENERLRRELRAGPQEERALLRQLKEVTDRQRDELRAHNRDLRQRGQETEA 143
A QE RL+ E E L+++ ++ R L +++ + +E + R L Q
Sbjct: 2322 AVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLE 2381
Query: 144 LQEQLQRLLLVNAELRHKLAAMQTQLRAAQDRERERQQPGEAA-----TPQAKERARGQA 198
+ + +RL L AE+ + Q RA +D +R R+Q E T A +
Sbjct: 2382 MSAEAERLKLRVAEM------SRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLV 2435
Query: 199 GRPGHQHGQEPEWATAGAGAPGNPEDPAEAAQQLGRPSEAGQCRFSREEFEQILQERNEL 258
Q Q A A E E QQ + + + EQ+LQE L
Sbjct: 2436 QTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQAL 2495
Query: 259 KAKVFLLKEELAYFQR----------ELLTDHRVPGLLLEAMKVAVRKQRKKIKAKMLGT 308
+ K+ L +R +L D L + ++Q ++ + +++ +
Sbjct: 2496 QQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVAS 2555
Query: 309 PEEAESSEDEA 319
EEA + EA
Sbjct: 2556 MEEARRRQHEA 2566
Score = 39.3 bits (90), Expect = 0.006
Identities = 82/337 (24%), Positives = 124/337 (36%), Gaps = 34/337 (10%)
Query: 49 EAAAGLVPLVVRALELLEQAA-VGPAPDSLQVSAQPAEQELRRLREENERLRRELRAGPQ 107
EA AG R EL E+AA + + + Q AE++ R R E ER+ E A
Sbjct: 1794 EAEAG------RFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIG 1847
Query: 108 EERALLRQLKEVTDRQRDELRAHNRDLRQRGQETEALQEQLQRLLLVNAELRHK--LAAM 165
E +LK + E A N LR+ ++ E QR L +HK +
Sbjct: 1848 EAT----RLKTEAEIALKEKEAENERLRRLAED-----EAFQRRRLEEQAAQHKADIEER 1898
Query: 166 QTQLRAAQDRERERQQPGEAATPQAKERARGQAGRPGHQHGQEPEWATAGAG-------- 217
QLR A D E ERQ+ + R R Q E A AG
Sbjct: 1899 LAQLRKASDSELERQK----GLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGR 1954
Query: 218 APGNPEDPAEAAQQLGRPSEAGQCRFSREEFEQILQERNELKAKVFLLKEELAYFQRELL 277
N ED + +Q EA + R E E+ +E E K +EE A ++ L
Sbjct: 1955 IRSNAEDTLRSKEQ--AELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAAL 2012
Query: 278 TD-HRVPGLLLEAMKVAVRKQRKKIKAKMLGTPEEAESSEDEAGPWILLSDDKGDHPPPP 336
+ R+ + EA ++ R +++ + L + + E K
Sbjct: 2013 EEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQT 2072
Query: 337 ESKIQSFFGLWYRGKAESSEDETSSPAPSKLGGEEEA 373
+ QS RG+AE++ +++ E EA
Sbjct: 2073 LQQEQSVLD-QLRGEAEAARRAAEEAEEARVQAEREA 2108
Score = 35.8 bits (81), Expect = 0.071
Identities = 36/142 (25%), Positives = 63/142 (44%), Gaps = 6/142 (4%)
Query: 57 LVVRALELLEQAAVGPAPDSLQVSAQPAEQELRRLREENERLRRELRAGPQEERALLRQL 116
L+ + EL ++ A D Q++ Q AE+ R +R+L + ER LR
Sbjct: 2335 LLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLR-- 2392
Query: 117 KEVTDRQRDELRAHNRDLRQRGQETEALQEQLQRLLLVNAELRHKLAAMQTQLRAAQDRE 176
V + R + RA D ++ ++ E + E+L R L E + ++ Q R D +
Sbjct: 2393 --VAEMSRAQARA-EEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQ-RQQSDHD 2448
Query: 177 RERQQPGEAATPQAKERARGQA 198
ER + A + KE+ + +A
Sbjct: 2449 AERLREAIAELEREKEKLQQEA 2470
Score = 35.0 bits (79), Expect = 0.12
Identities = 33/119 (27%), Positives = 50/119 (42%), Gaps = 14/119 (11%)
Query: 75 DSLQVSAQPAEQELRRLREENERLRRELRAGPQEERALLRQLKEVTDRQ----------R 124
+ LQ Q Q+ L EEN+RLR +L+ ++ RA L +EVT Q R
Sbjct: 2575 EELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGR 2634
Query: 125 DELRAHNRDLRQR----GQETEALQEQLQRLLLVNAELRHKLAAMQTQLRAAQDRERER 179
D L + G + ++LQ +++AE +LA T + RE R
Sbjct: 2635 DALDGPAAEAEPEHSFDGLRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVR 2693
Score = 33.9 bits (76), Expect = 0.27
Identities = 47/207 (22%), Positives = 90/207 (43%), Gaps = 23/207 (11%)
Query: 84 AEQELRRLREENERLRRELRAGP--QEERALLRQLKEVTDRQRDELRAHNRD-LRQRGQE 140
AE++ +R R++ E + +L +E+ L Q E+ +Q D R+ + + +E
Sbjct: 2403 AEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELERE 2462
Query: 141 TEALQEQLQRLLLVNAELR--------HKLAAMQTQLRAAQDR--ERERQQPGEAATPQ- 189
E LQ++ + L L + E++ + A+Q + +D +RER E A +
Sbjct: 2463 KEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQ 2522
Query: 190 -------AKERARGQAGRPGHQHGQEPEWATAGAGAPGNPEDPAEAAQQLGRPSEAGQCR 242
++ R + R Q QE + A + AE + + E Q
Sbjct: 2523 LFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVR-RKQEELQQLE 2581
Query: 243 FSREEFEQILQERNE-LKAKVFLLKEE 268
R + E++L E N+ L+ ++ LL+E+
Sbjct: 2582 QQRRQQEELLAEENQRLREQLQLLEEQ 2608
Score = 33.5 bits (75), Expect = 0.35
Identities = 63/248 (25%), Positives = 98/248 (39%), Gaps = 33/248 (13%)
Query: 59 VRALELLEQAAVGPAPDSLQVSAQPAEQELRRLREENERLRRELRAGPQEERALLRQ--- 115
V E L+Q+A A Q AQ A ++LR+ E E RR Q E+A LRQ
Sbjct: 2115 VEEAERLKQSAEEQAQARAQ--AQAAAEKLRK-EAEQEAARRA-----QAEQAALRQKQA 2166
Query: 116 ----------LKEVTDRQRDELRAHNRDLRQRGQETE----ALQEQLQRLLLVNAELRHK 161
E T RQ+ ++ LR + +ET+ L E+LQRL E +
Sbjct: 2167 ADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQ 2226
Query: 162 LAAMQTQL---RAAQDRERERQQPGEAATPQAKERARGQAGRPGHQHGQEPEWATAGAGA 218
+ ++ +L R + + + EA R + R + ++ + A
Sbjct: 2227 RSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAAR 2286
Query: 219 PGNPEDPAEAAQQLGRPSEAGQCRFSR---EEFEQILQERNELKAKVFLLKE--ELAYFQ 273
A +QL A Q + +E Q +QE LKA+ LL++ ELA Q
Sbjct: 2287 LSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQ 2346
Query: 274 RELLTDHR 281
L + +
Sbjct: 2347 ARRLQEDK 2354
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 47.4 bits (111), Expect = 2e-05
Identities = 80/321 (24%), Positives = 139/321 (43%), Gaps = 48/321 (14%)
Query: 21 SASAAELVYHLAGALGTELQDLARRFGPEAAAGLVPLVVRALELLEQAAVGPAPDSLQVS 80
+A AEL L G + + +D R + A L R L E+ A + +Q S
Sbjct: 1938 AAGKAELELEL-GRIRSNAEDTLRS---KEQAELEAARQRQLAAEEERRRREAEERVQKS 1993
Query: 81 AQPAEQELRRLR---EENERLR------RELRAGPQEERALLRQLKEVTDRQR--DELRA 129
E+ R+ + EE ERL+ R LR ++E A QL + ++R E +A
Sbjct: 1994 LAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKA 2053
Query: 130 HNRDLRQRGQETEALQEQLQRLLLVNAELRHKL------------AAMQTQLRAAQDRER 177
H ++Q+ QE LQ+ LQ+ V +LR + A +Q + AAQ R +
Sbjct: 2054 HAFAVQQKEQE---LQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQ 2110
Query: 178 --ERQQPGEAATPQAKERARGQAGRPGHQHGQEPEWATAGAGAPGNPEDPAEAAQQLGRP 235
E ++ ++A QA+ RA+ QA + E E A A+A Q R
Sbjct: 2111 VEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARR-----------AQAEQAALRQ 2159
Query: 236 SEAGQCRFSREE--FEQILQERNELKAKVFLLKEELAYFQREL-LTDHRVPGLLLEAMKV 292
+A + + EQ L+++ +++ ++ L+ +L + L D + L EA +
Sbjct: 2160 KQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEA 2219
Query: 293 AVRKQRKKIKAKMLGTPEEAE 313
A +QR +++ ++ + E
Sbjct: 2220 A--RQRSQVEEELFSVRVQME 2238
Score = 46.2 bits (108), Expect = 5e-05
Identities = 83/336 (24%), Positives = 129/336 (38%), Gaps = 76/336 (22%)
Query: 54 LVPLVVRALELLEQAAVGPAPDSLQVSAQPAEQELRRLREENERLRRELRAGPQEER--- 110
+V L + A E A G +L+ A+ AE + R+ +EE ERLRR+++ Q +R
Sbjct: 1456 VVRLQLEATERQRGGAEGEL-QALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAE 1514
Query: 111 -ALLRQLKEVTDRQRDELRA-------------HNRDLRQ----RGQETEALQEQLQRLL 152
L ++K + R++ RA R LRQ R ++ + E QR
Sbjct: 1515 VELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQR-- 1572
Query: 153 LVNAELRHKLAAMQ-----------------TQLRAAQDRERERQQPGEAATPQAKE--- 192
AEL+ K A+ QLR +R ++Q E A +A+
Sbjct: 1573 SAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELE 1632
Query: 193 ----------RARGQAGRPGHQHG-------QEPEWATAGAGAPGNPEDPAEAAQQLGRP 235
R R QA Q ++ E A A G E+ A ++L
Sbjct: 1633 RWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQ 1692
Query: 236 SEAGQCRFSREEFEQILQERNEL----------KAKVFLLKEELAYFQRE--LLTDHRVP 283
Q + + +Q L EL + + LL+EELA QRE T R
Sbjct: 1693 ELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQE 1752
Query: 284 GLLLEAMKVAVRKQRKKIKAKMLGTPEEAESSEDEA 319
LEA VR + + + A EE+ S+ +++
Sbjct: 1753 ---LEAELAKVRAEMEVLLASKARAEEESRSTSEKS 1785
Score = 45.4 bits (106), Expect = 9e-05
Identities = 61/223 (27%), Positives = 94/223 (42%), Gaps = 31/223 (13%)
Query: 81 AQPAEQELRRLREENERLRRELRAGPQEERALLRQLKEVTDRQRDELRAHNRDLRQRGQE 140
AQ +E +R +++ E+ R+ L A +E R + +E R+++EL+ + QR Q+
Sbjct: 2527 AQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQ---QRRQQ 2583
Query: 141 TEALQEQLQRLLLVNAELRHKLAAMQTQLRAAQDRERERQQPGEAATPQAKERARGQAGR 200
E L E+ QRL R +L ++ Q RAA E AAT K G+
Sbjct: 2584 EELLAEENQRL-------REQLQLLEEQHRAALAHSEEVTASQVAAT---KTLPNGRDAL 2633
Query: 201 PGHQHGQEPEWATAGAGAPGNPED-------PAEAAQQLGRPSEAGQCRFSREEFEQILQ 253
G EPE + G + + AE Q+L + RE+ LQ
Sbjct: 2634 DGPAAEAEPEHSFDGLRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQ 2693
Query: 254 ERNELKAKVFLLKEE----LAYFQRELLTDHRVPG---LLLEA 289
R+ + + E A QR+LL+ PG +LLEA
Sbjct: 2694 GRSSIAGLLLKATNEKLSVYAALQRQLLS----PGTALILLEA 2732
Score = 45.1 bits (105), Expect = 1e-04
Identities = 55/190 (28%), Positives = 89/190 (46%), Gaps = 15/190 (7%)
Query: 86 QELRRLREENERLRRELRAGPQEERALLRQLKEVTDRQRDELRAHNRDLRQRGQETEALQ 145
+ LRR+ EE ERL + RA EER L +++ ++QR AH + Q +E + LQ
Sbjct: 1339 ETLRRMEEE-ERLAEQQRA---EERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQ 1394
Query: 146 EQLQRLLLVNAELRHKLAAM--QTQLRAAQDRERERQQPGEAATPQAKERARGQAGRPGH 203
+++Q + +R + AA+ Q Q R+ Q+ ++ +Q EA QAK R A R
Sbjct: 1395 QRMQEEV-----VRREEAAVDAQQQKRSIQEELQQLRQSSEAEI-QAKARQAEAAERSRL 1448
Query: 204 QHGQEPEWATAGAGAPGNPEDPAEAAQQL--GRPSEA-GQCRFSREEFEQILQERNELKA 260
+ +E A AE Q R EA Q R ++EE E++ ++ +
Sbjct: 1449 RIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQ 1508
Query: 261 KVFLLKEELA 270
+ + ELA
Sbjct: 1509 RKRQAEVELA 1518
Score = 44.3 bits (103), Expect = 2e-04
Identities = 58/223 (26%), Positives = 98/223 (43%), Gaps = 26/223 (11%)
Query: 57 LVVRALELLEQAAVGPAPDSLQVSAQPAEQELRRLREENERLRRELRAGPQEERALLRQL 116
L ++A E+ +Q ++ A Q + AE+E RR + E+ R+ R ++E RQL
Sbjct: 1644 LRLQAEEVAQQKSLAQAEAEKQ--KEEAEREARRRGKAEEQAVRQ-RELAEQELEKQRQL 1700
Query: 117 KEVTDRQR----DELRAHNRDLRQRGQETEALQEQLQRLLLVNA-------ELRHKLAAM 165
E T +QR EL + Q Q+ + L+E+L RL A EL +LA +
Sbjct: 1701 AEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKV 1760
Query: 166 QTQLRAAQDRERERQQPGEAATPQAKERARGQAGRPGHQHGQEPEWATAGAGAPGNPEDP 225
+ ++ + ++ + + ++K+R +AGR E A A E+
Sbjct: 1761 RAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGR-------FRELAEEAARLRALAEE- 1812
Query: 226 AEAAQQLGRPSEAGQCRFSREEFEQILQERNELKAKVFLLKEE 268
A+ +QL A Q R E E++L E+ + LK E
Sbjct: 1813 AKRQRQLAEEDAARQ----RAEAERVLAEKLAAIGEATRLKTE 1851
Score = 43.5 bits (101), Expect = 3e-04
Identities = 59/255 (23%), Positives = 103/255 (40%), Gaps = 35/255 (13%)
Query: 75 DSLQVSAQPAEQELRRLREENERLRRELRAGPQEERALLRQLKEVTDRQRDELRAHNRDL 134
+ LQ Q +E E++ + E R R +EE ++R E T+RQR + L
Sbjct: 1420 EELQQLRQSSEAEIQAKARQAEAAERS-RLRIEEEIRVVRLQLEATERQRGGAEGELQAL 1478
Query: 135 RQRGQETEALQEQLQRLLLVNAELRHKLAAMQTQLRAAQDRERERQQPGEAATPQAKERA 194
R R +E EA + Q Q A + + + + +R+RQ E A ++ +A
Sbjct: 1479 RARAEEAEAQKRQAQE------------EAERLRRQVQDESQRKRQAEVELA---SRVKA 1523
Query: 195 RGQAGRPGHQHGQEPEWATAGAGAPGNPEDPAEAAQQLGRPSEAGQCRFSREEFEQILQE 254
+A R + Q E AE A++ R +E + R + E +
Sbjct: 1524 EAEAAREKQRALQALEELRL----------QAEEAERRLRQAEVERARQVQVALETAQRS 1573
Query: 255 RN-ELKAKVFLLKEELAYFQRELLTDHRVPGLLLEAMKVAVRKQRKKIKAKMLGTPEEAE 313
EL++K E+ A +R L +H L E + ++Q + +A+ E
Sbjct: 1574 AEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAR--------E 1625
Query: 314 SSEDEAGPWILLSDD 328
+E E W L +++
Sbjct: 1626 EAERELERWQLKANE 1640
Score = 43.5 bits (101), Expect = 3e-04
Identities = 55/251 (21%), Positives = 95/251 (37%), Gaps = 21/251 (8%)
Query: 84 AEQELRRLREENERLRRELRAGPQEERALLRQLKEVTDRQRDELRAHNRDLRQRGQETEA 143
A QE RL+ E E L+++ ++ R L +++ + +E + R L Q
Sbjct: 2318 AVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLE 2377
Query: 144 LQEQLQRLLLVNAELRHKLAAMQTQLRAAQDRERERQQPGEAA-----TPQAKERARGQA 198
+ + +RL L AE+ + Q RA +D +R R+Q E T A +
Sbjct: 2378 MSAEAERLKLRVAEM------SRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLV 2431
Query: 199 GRPGHQHGQEPEWATAGAGAPGNPEDPAEAAQQLGRPSEAGQCRFSREEFEQILQERNEL 258
Q Q A A E E QQ + + + EQ+LQE L
Sbjct: 2432 QTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQAL 2491
Query: 259 KAKVFLLKEELAYFQR----------ELLTDHRVPGLLLEAMKVAVRKQRKKIKAKMLGT 308
+ K+ L +R +L D L + ++Q ++ + +++ +
Sbjct: 2492 QQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVAS 2551
Query: 309 PEEAESSEDEA 319
EEA + EA
Sbjct: 2552 MEEARRRQHEA 2562
Score = 39.3 bits (90), Expect = 0.006
Identities = 82/337 (24%), Positives = 124/337 (36%), Gaps = 34/337 (10%)
Query: 49 EAAAGLVPLVVRALELLEQAA-VGPAPDSLQVSAQPAEQELRRLREENERLRRELRAGPQ 107
EA AG R EL E+AA + + + Q AE++ R R E ER+ E A
Sbjct: 1790 EAEAG------RFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIG 1843
Query: 108 EERALLRQLKEVTDRQRDELRAHNRDLRQRGQETEALQEQLQRLLLVNAELRHK--LAAM 165
E +LK + E A N LR+ ++ E QR L +HK +
Sbjct: 1844 EAT----RLKTEAEIALKEKEAENERLRRLAED-----EAFQRRRLEEQAAQHKADIEER 1894
Query: 166 QTQLRAAQDRERERQQPGEAATPQAKERARGQAGRPGHQHGQEPEWATAGAG-------- 217
QLR A D E ERQ+ + R R Q E A AG
Sbjct: 1895 LAQLRKASDSELERQK----GLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGR 1950
Query: 218 APGNPEDPAEAAQQLGRPSEAGQCRFSREEFEQILQERNELKAKVFLLKEELAYFQRELL 277
N ED + +Q EA + R E E+ +E E K +EE A ++ L
Sbjct: 1951 IRSNAEDTLRSKEQ--AELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAAL 2008
Query: 278 TD-HRVPGLLLEAMKVAVRKQRKKIKAKMLGTPEEAESSEDEAGPWILLSDDKGDHPPPP 336
+ R+ + EA ++ R +++ + L + + E K
Sbjct: 2009 EEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQT 2068
Query: 337 ESKIQSFFGLWYRGKAESSEDETSSPAPSKLGGEEEA 373
+ QS RG+AE++ +++ E EA
Sbjct: 2069 LQQEQSVLD-QLRGEAEAARRAAEEAEEARVQAEREA 2104
Score = 35.8 bits (81), Expect = 0.071
Identities = 36/142 (25%), Positives = 63/142 (44%), Gaps = 6/142 (4%)
Query: 57 LVVRALELLEQAAVGPAPDSLQVSAQPAEQELRRLREENERLRRELRAGPQEERALLRQL 116
L+ + EL ++ A D Q++ Q AE+ R +R+L + ER LR
Sbjct: 2331 LLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLR-- 2388
Query: 117 KEVTDRQRDELRAHNRDLRQRGQETEALQEQLQRLLLVNAELRHKLAAMQTQLRAAQDRE 176
V + R + RA D ++ ++ E + E+L R L E + ++ Q R D +
Sbjct: 2389 --VAEMSRAQARA-EEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQ-RQQSDHD 2444
Query: 177 RERQQPGEAATPQAKERARGQA 198
ER + A + KE+ + +A
Sbjct: 2445 AERLREAIAELEREKEKLQQEA 2466
Score = 35.0 bits (79), Expect = 0.12
Identities = 33/119 (27%), Positives = 50/119 (42%), Gaps = 14/119 (11%)
Query: 75 DSLQVSAQPAEQELRRLREENERLRRELRAGPQEERALLRQLKEVTDRQ----------R 124
+ LQ Q Q+ L EEN+RLR +L+ ++ RA L +EVT Q R
Sbjct: 2571 EELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGR 2630
Query: 125 DELRAHNRDLRQR----GQETEALQEQLQRLLLVNAELRHKLAAMQTQLRAAQDRERER 179
D L + G + ++LQ +++AE +LA T + RE R
Sbjct: 2631 DALDGPAAEAEPEHSFDGLRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVR 2689
Score = 33.9 bits (76), Expect = 0.27
Identities = 47/207 (22%), Positives = 90/207 (43%), Gaps = 23/207 (11%)
Query: 84 AEQELRRLREENERLRRELRAGP--QEERALLRQLKEVTDRQRDELRAHNRD-LRQRGQE 140
AE++ +R R++ E + +L +E+ L Q E+ +Q D R+ + + +E
Sbjct: 2399 AEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELERE 2458
Query: 141 TEALQEQLQRLLLVNAELR--------HKLAAMQTQLRAAQDR--ERERQQPGEAATPQ- 189
E LQ++ + L L + E++ + A+Q + +D +RER E A +
Sbjct: 2459 KEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQ 2518
Query: 190 -------AKERARGQAGRPGHQHGQEPEWATAGAGAPGNPEDPAEAAQQLGRPSEAGQCR 242
++ R + R Q QE + A + AE + + E Q
Sbjct: 2519 LFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVR-RKQEELQQLE 2577
Query: 243 FSREEFEQILQERNE-LKAKVFLLKEE 268
R + E++L E N+ L+ ++ LL+E+
Sbjct: 2578 QQRRQQEELLAEENQRLREQLQLLEEQ 2604
Score = 33.5 bits (75), Expect = 0.35
Identities = 63/248 (25%), Positives = 98/248 (39%), Gaps = 33/248 (13%)
Query: 59 VRALELLEQAAVGPAPDSLQVSAQPAEQELRRLREENERLRRELRAGPQEERALLRQ--- 115
V E L+Q+A A Q AQ A ++LR+ E E RR Q E+A LRQ
Sbjct: 2111 VEEAERLKQSAEEQAQARAQ--AQAAAEKLRK-EAEQEAARRA-----QAEQAALRQKQA 2162
Query: 116 ----------LKEVTDRQRDELRAHNRDLRQRGQETE----ALQEQLQRLLLVNAELRHK 161
E T RQ+ ++ LR + +ET+ L E+LQRL E +
Sbjct: 2163 ADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQ 2222
Query: 162 LAAMQTQL---RAAQDRERERQQPGEAATPQAKERARGQAGRPGHQHGQEPEWATAGAGA 218
+ ++ +L R + + + EA R + R + ++ + A
Sbjct: 2223 RSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAAR 2282
Query: 219 PGNPEDPAEAAQQLGRPSEAGQCRFSR---EEFEQILQERNELKAKVFLLKE--ELAYFQ 273
A +QL A Q + +E Q +QE LKA+ LL++ ELA Q
Sbjct: 2283 LSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQ 2342
Query: 274 RELLTDHR 281
L + +
Sbjct: 2343 ARRLQEDK 2350
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.129 0.368
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,256,290
Number of Sequences: 37866
Number of extensions: 1004020
Number of successful extensions: 11887
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 291
Number of HSP's successfully gapped in prelim test: 812
Number of HSP's that attempted gapping in prelim test: 7431
Number of HSP's gapped (non-prelim): 3774
length of query: 401
length of database: 18,247,518
effective HSP length: 104
effective length of query: 297
effective length of database: 14,309,454
effective search space: 4249907838
effective search space used: 4249907838
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.