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Search of human proteins with 93141031
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|93141031 paralemmin isoform 1 [Homo sapiens]
(387 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|93141031 paralemmin isoform 1 [Homo sapiens] 756 0.0
gi|93141029 paralemmin isoform 2 [Homo sapiens] 651 0.0
gi|82524851 paralemmin 2 isoform a [Homo sapiens] 237 2e-62
gi|82617626 paralemmin 2 isoform b [Homo sapiens] 231 6e-61
gi|8923243 palmdelphin [Homo sapiens] 129 4e-30
gi|22325356 PALM2-AKAP2 protein isoform 2 [Homo sapiens] 110 2e-24
gi|6005709 PALM2-AKAP2 protein isoform 1 [Homo sapiens] 110 2e-24
gi|222537747 hypothetical protein LOC342979 [Homo sapiens] 70 2e-12
gi|187761324 shootin1 isoform a [Homo sapiens] 57 3e-08
gi|78042577 MAP7 domain containing 1 [Homo sapiens] 54 2e-07
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 54 3e-07
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 54 3e-07
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 54 3e-07
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 54 3e-07
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 54 3e-07
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 54 3e-07
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 54 3e-07
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 54 3e-07
gi|22035602 mitogen-activated protein kinase kinase kinase kinas... 50 3e-06
gi|15826852 acyl-Coenzyme A binding domain containing 3 [Homo sa... 47 3e-05
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 46 6e-05
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 46 6e-05
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 46 6e-05
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 46 6e-05
gi|50511340 shootin1 isoform b [Homo sapiens] 46 6e-05
gi|22035606 mitogen-activated protein kinase kinase kinase kinas... 45 8e-05
gi|239735588 TRAF2 and NCK interacting kinase isoform 6 [Homo sa... 45 1e-04
gi|239735586 TRAF2 and NCK interacting kinase isoform 5 [Homo sa... 45 1e-04
gi|56549694 enabled homolog isoform a [Homo sapiens] 44 2e-04
gi|39930375 enabled homolog isoform b [Homo sapiens] 44 2e-04
>gi|93141031 paralemmin isoform 1 [Homo sapiens]
Length = 387
Score = 756 bits (1952), Expect = 0.0
Identities = 387/387 (100%), Positives = 387/387 (100%)
Query: 1 MEVLAAETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTP 60
MEVLAAETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTP
Sbjct: 1 MEVLAAETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTP 60
Query: 61 SSASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAAPSPVRA 120
SSASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAAPSPVRA
Sbjct: 61 SSASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAAPSPVRA 120
Query: 121 PAPSPAKEERKTEVVMNSQQTPVGTPKDKRVSNTPLRTVDGSPMMKAAMYSVEITVEKDK 180
PAPSPAKEERKTEVVMNSQQTPVGTPKDKRVSNTPLRTVDGSPMMKAAMYSVEITVEKDK
Sbjct: 121 PAPSPAKEERKTEVVMNSQQTPVGTPKDKRVSNTPLRTVDGSPMMKAAMYSVEITVEKDK 180
Query: 181 VTGETRVLSSTTLLPRQPLPLGIKVYEDETKVVHAVDGTAENGIHPLSSSEVDELIHKAD 240
VTGETRVLSSTTLLPRQPLPLGIKVYEDETKVVHAVDGTAENGIHPLSSSEVDELIHKAD
Sbjct: 181 VTGETRVLSSTTLLPRQPLPLGIKVYEDETKVVHAVDGTAENGIHPLSSSEVDELIHKAD 240
Query: 241 EVTLSEAGSTAGAAETRGAVEGAARTTPSRREITGVQAQPGEATSGPPGIQPGQEPPVTM 300
EVTLSEAGSTAGAAETRGAVEGAARTTPSRREITGVQAQPGEATSGPPGIQPGQEPPVTM
Sbjct: 241 EVTLSEAGSTAGAAETRGAVEGAARTTPSRREITGVQAQPGEATSGPPGIQPGQEPPVTM 300
Query: 301 IFMGYQNVEDEAETKKVLGLQDTITAELVVIEDAAEPKEPAPPNGSAAEPPTEAASREEN 360
IFMGYQNVEDEAETKKVLGLQDTITAELVVIEDAAEPKEPAPPNGSAAEPPTEAASREEN
Sbjct: 301 IFMGYQNVEDEAETKKVLGLQDTITAELVVIEDAAEPKEPAPPNGSAAEPPTEAASREEN 360
Query: 361 QAGPEATTSDPQDLDMKKHRCKCCSIM 387
QAGPEATTSDPQDLDMKKHRCKCCSIM
Sbjct: 361 QAGPEATTSDPQDLDMKKHRCKCCSIM 387
>gi|93141029 paralemmin isoform 2 [Homo sapiens]
Length = 343
Score = 651 bits (1679), Expect = 0.0
Identities = 343/387 (88%), Positives = 343/387 (88%), Gaps = 44/387 (11%)
Query: 1 MEVLAAETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTP 60
MEVLAAETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTP
Sbjct: 1 MEVLAAETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTP 60
Query: 61 SSASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAAPSPVRA 120
SSASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAAPSPVRA
Sbjct: 61 SSASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAAPSPVRA 120
Query: 121 PAPSPAKEERKTEVVMNSQQTPVGTPKDKRVSNTPLRTVDGSPMMKAAMYSVEITVEKDK 180
PAPSPAKEERKTEVVMNSQQTPVGTPKDKRVSNTPLRTVDGSPMMKA
Sbjct: 121 PAPSPAKEERKTEVVMNSQQTPVGTPKDKRVSNTPLRTVDGSPMMKA------------- 167
Query: 181 VTGETRVLSSTTLLPRQPLPLGIKVYEDETKVVHAVDGTAENGIHPLSSSEVDELIHKAD 240
VVHAVDGTAENGIHPLSSSEVDELIHKAD
Sbjct: 168 -------------------------------VVHAVDGTAENGIHPLSSSEVDELIHKAD 196
Query: 241 EVTLSEAGSTAGAAETRGAVEGAARTTPSRREITGVQAQPGEATSGPPGIQPGQEPPVTM 300
EVTLSEAGSTAGAAETRGAVEGAARTTPSRREITGVQAQPGEATSGPPGIQPGQEPPVTM
Sbjct: 197 EVTLSEAGSTAGAAETRGAVEGAARTTPSRREITGVQAQPGEATSGPPGIQPGQEPPVTM 256
Query: 301 IFMGYQNVEDEAETKKVLGLQDTITAELVVIEDAAEPKEPAPPNGSAAEPPTEAASREEN 360
IFMGYQNVEDEAETKKVLGLQDTITAELVVIEDAAEPKEPAPPNGSAAEPPTEAASREEN
Sbjct: 257 IFMGYQNVEDEAETKKVLGLQDTITAELVVIEDAAEPKEPAPPNGSAAEPPTEAASREEN 316
Query: 361 QAGPEATTSDPQDLDMKKHRCKCCSIM 387
QAGPEATTSDPQDLDMKKHRCKCCSIM
Sbjct: 317 QAGPEATTSDPQDLDMKKHRCKCCSIM 343
>gi|82524851 paralemmin 2 isoform a [Homo sapiens]
Length = 413
Score = 237 bits (604), Expect = 2e-62
Identities = 160/422 (37%), Positives = 231/422 (54%), Gaps = 52/422 (12%)
Query: 6 AETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSASE 65
AE +ERLQAIAEKRKRQ EIE KR+QL+++ LQH KSK LRE+WLL+G P+ +E
Sbjct: 4 AEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAE 63
Query: 66 GDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAAPSPVRAPAPSP 125
+E RRQ ++DE + + LED++ RLE+EI+ LE + + +AKE +
Sbjct: 64 EEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLE-SEESQISAKEQI-----ILEKLKET 117
Query: 126 AKEERKTEVVMNSQQTPVGTPKDKRVSNTPL---RTVDGSP-----MMKAAMYSVEITVE 177
K + + +S ++ + P+ RT + SP AA+Y++EI VE
Sbjct: 118 EKSFKDFQKGFSSTDGDAVNYISSQLPDLPILCSRTAEPSPGQDGTSRAAAVYAMEINVE 177
Query: 178 KDKVTGETRVLSSTTLLPRQPLPLGIKVYEDETKVVHAV--DGT-AENGIHPLSSSEVDE 234
KDK TGET++LS++T+ P G+KVY+D TKVV+ V GT ENG+H LS+ +V+E
Sbjct: 178 KDKQTGETKILSTSTIGPEGVHQKGVKVYDDGTKVVYEVRSGGTVVENGVHKLSTKDVEE 237
Query: 235 LIHKADEVTLSEAGSTAGAAETRGAVEGAARTTPSRR------EITGVQAQPGEATSGPP 288
LI KA + +L G R + + + P ++ V + +SG P
Sbjct: 238 LIQKAGQSSLG-----GGHVSERTVIADGSLSHPKEHMLCKEAKLEMVHKSRKDHSSGNP 292
Query: 289 GIQPGQEP-----------PVTMIFMGYQNVEDEAETKKVLGLQDTITAELVVIEDAAEP 337
G Q Q P PVTMIFMGYQN+EDE ETKKVLG +TI AELV+I++ E
Sbjct: 293 G-QQAQAPSAAGPEANLDQPVTMIFMGYQNIEDEEETKKVLGYDETIKAELVLIDEDDEK 351
Query: 338 K-------EPAPPNGSAAE-----PPTEAASREENQAGPEATTSDPQDLDMKKHRCKCCS 385
+ + +G+AAE P ++ + E+ ++P KK RC+CC
Sbjct: 352 SLREKTVTDVSTIDGNAAELVSGRPVSDTTEPSSPEGKEESLATEPAPGTQKKKRCQCCV 411
Query: 386 IM 387
+M
Sbjct: 412 VM 413
>gi|82617626 paralemmin 2 isoform b [Homo sapiens]
Length = 379
Score = 231 bits (590), Expect = 6e-61
Identities = 161/414 (38%), Positives = 227/414 (54%), Gaps = 70/414 (16%)
Query: 6 AETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSASE 65
AE +ERLQAIAEKRKRQ EIE KR+QL+++ LQH KSK LRE+WLL+G P+ +E
Sbjct: 4 AEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAE 63
Query: 66 GDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAAPSPVRAPAPSP 125
+E RRQ ++DE + + LED++ RLE+EI+ LE +S +AKE
Sbjct: 64 EEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQ-ISAKEQIIL----------- 111
Query: 126 AKEERKTEVVMNSQQTPVGTPKDKRVSNTPLRTVDGSPMMKAAMYSVEITVEKDKVTGET 185
++ ++TE Q K S+T DG A+Y++EI VEKDK TGET
Sbjct: 112 -EKLKETEKSFKDFQ--------KGFSST-----DG------AVYAMEINVEKDKQTGET 151
Query: 186 RVLSSTTLLPRQPLPLGIKVYEDETKVVHAV--DGTA-ENGIHPLSSSEVDELIHKADEV 242
++LS++T+ P G+KVY+D TKVV+ V GT ENG+H LS+ +V+ELI KA +
Sbjct: 152 KILSTSTIGPEGVHQKGVKVYDDGTKVVYEVRSGGTVVENGVHKLSTKDVEELIQKAGQS 211
Query: 243 TLSEAGSTAGAAETRGAVEGAARTTPSRR------EITGVQAQPGEATSGPPGIQPGQEP 296
+L G R + + + P ++ V + +SG PG Q Q P
Sbjct: 212 SLG-----GGHVSERTVIADGSLSHPKEHMLCKEAKLEMVHKSRKDHSSGNPG-QQAQAP 265
Query: 297 -----------PVTMIFMGYQNVEDEAETKKVLGLQDTITAELVVIEDAAEPK------- 338
PVTMIFMGYQN+EDE ETKKVLG +TI AELV+I++ E
Sbjct: 266 SAAGPEANLDQPVTMIFMGYQNIEDEEETKKVLGYDETIKAELVLIDEDDEKSLREKTVT 325
Query: 339 EPAPPNGSAAE-----PPTEAASREENQAGPEATTSDPQDLDMKKHRCKCCSIM 387
+ + +G+AAE P ++ + E+ ++P KK RC+CC +M
Sbjct: 326 DVSTIDGNAAELVSGRPVSDTTEPSSPEGKEESLATEPAPGTQKKKRCQCCVVM 379
>gi|8923243 palmdelphin [Homo sapiens]
Length = 551
Score = 129 bits (324), Expect = 4e-30
Identities = 88/241 (36%), Positives = 132/241 (54%), Gaps = 15/241 (6%)
Query: 14 RLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSASEGDEDLRRQ 73
RLQAI +KRK Q EI KR ++E+++ + QHLK KALRE+WLL+G S+ + E++++Q
Sbjct: 10 RLQAITDKRKIQEEISQKRLKIEEDKLKHQHLKKKALREKWLLDGI--SSGKEQEEMKKQ 67
Query: 74 MQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKE-------NAAAPSPVRAPAPSPA 126
Q D+ + ++LE S+ RLEKEI+ LE+ + +T +E + + +
Sbjct: 68 NQQDQHQIQVLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKSIERTTEDIIRSVKVE 127
Query: 127 KEERKTEVVMNSQQTPVGTPKD---KRVSNTPLRTVDGSPMMKAAMYSVEITVEKDKVTG 183
+EER E + + PK R+ + + A+Y++EI VEKD TG
Sbjct: 128 REERAEESIEDIYANIPDLPKSYIPSRLRKEINEEKEDDEQNRKALYAMEIKVEKDLKTG 187
Query: 184 ETRVLSSTTLLPRQPLPLGIKVYEDETKVVHAVD---GTAENGIHPLSSSEVDELIHKAD 240
E+ VLSS L GIKVY+D K V+AV A NG L+ EV+EL+ +A
Sbjct: 188 ESTVLSSIPLPSDDFKGTGIKVYDDGQKSVYAVSSNHSAAYNGTDGLAPVEVEELLRQAS 247
Query: 241 E 241
E
Sbjct: 248 E 248
Score = 52.8 bits (125), Expect = 5e-07
Identities = 39/95 (41%), Positives = 47/95 (49%), Gaps = 15/95 (15%)
Query: 287 PPGIQPGQEPPVTMIFMGYQNVEDEAETKKVL-GLQDTITAELVVIEDAAEPKE------ 339
PP I + PVTMIFMGYQ ED E KK L G I AELVVI+D E E
Sbjct: 404 PPDINDTE--PVTMIFMGYQQAEDSEEDKKFLTGYDGIIHAELVVIDDEEEEDEGEAEKP 461
Query: 340 ---PAPPNGSAAEP--PTEAASREENQAGPEATTS 369
P P+ +P PT R+ ++A P T+
Sbjct: 462 SYHPIAPHSQVYQPAKPT-PLPRKRSEASPHENTN 495
>gi|22325356 PALM2-AKAP2 protein isoform 2 [Homo sapiens]
Length = 1090
Score = 110 bits (275), Expect = 2e-24
Identities = 83/258 (32%), Positives = 132/258 (51%), Gaps = 16/258 (6%)
Query: 6 AETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSASE 65
AE +ERLQAIAEKRKRQ EIE KR+QL+++ LQH KSK LRE+WLL+G P+ +E
Sbjct: 2 AEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAE 61
Query: 66 GDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAAPSPVRAPAPSP 125
+E RRQ ++DE + + LED++ RLE+EI+ LE + + +AKE +
Sbjct: 62 EEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLE-SEESQISAKEQI-----ILEKLKET 115
Query: 126 AKEERKTEVVMNSQQTPVGTPKDKRVSNTPL---RTVDGSP----MMKAAMYSVEITVEK 178
K + + +S ++ + P+ RT + SP +AA E + K
Sbjct: 116 EKSFKDFQKGFSSTDGDAVNYISSQLPDLPILCSRTAEPSPGQDGTSRAAGVGWENVLLK 175
Query: 179 DKVTGETRVLSSTTLLPRQPLPLGIKVYEDETKVVHAVDGTAENGIHPLSSSEVDELIHK 238
+ GE+ ++ T P + ++ ED+ + D + + P +SS + +
Sbjct: 176 E---GESASNATETSGPDMTIKKPPQLSEDDIWLKSEGDNYSATLLEPAASSLSPDHKNM 232
Query: 239 ADEVTLSEAGSTAGAAET 256
EV+++E S G T
Sbjct: 233 EIEVSVAECKSVPGITST 250
>gi|6005709 PALM2-AKAP2 protein isoform 1 [Homo sapiens]
Length = 1103
Score = 110 bits (275), Expect = 2e-24
Identities = 83/258 (32%), Positives = 132/258 (51%), Gaps = 16/258 (6%)
Query: 6 AETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSASE 65
AE +ERLQAIAEKRKRQ EIE KR+QL+++ LQH KSK LRE+WLL+G P+ +E
Sbjct: 2 AEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAE 61
Query: 66 GDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAAPSPVRAPAPSP 125
+E RRQ ++DE + + LED++ RLE+EI+ LE + + +AKE +
Sbjct: 62 EEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLE-SEESQISAKEQI-----ILEKLKET 115
Query: 126 AKEERKTEVVMNSQQTPVGTPKDKRVSNTPL---RTVDGSP----MMKAAMYSVEITVEK 178
K + + +S ++ + P+ RT + SP +AA E + K
Sbjct: 116 EKSFKDFQKGFSSTDGDAVNYISSQLPDLPILCSRTAEPSPGQDGTSRAAGVGWENVLLK 175
Query: 179 DKVTGETRVLSSTTLLPRQPLPLGIKVYEDETKVVHAVDGTAENGIHPLSSSEVDELIHK 238
+ GE+ ++ T P + ++ ED+ + D + + P +SS + +
Sbjct: 176 E---GESASNATETSGPDMTIKKPPQLSEDDIWLKSEGDNYSATLLEPAASSLSPDHKNM 232
Query: 239 ADEVTLSEAGSTAGAAET 256
EV+++E S G T
Sbjct: 233 EIEVSVAECKSVPGITST 250
>gi|222537747 hypothetical protein LOC342979 [Homo sapiens]
Length = 673
Score = 70.5 bits (171), Expect = 2e-12
Identities = 35/98 (35%), Positives = 63/98 (64%), Gaps = 4/98 (4%)
Query: 6 AETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSASE 65
AE++ ++RL+ IAEKR+ Q EI RR++E+E+ +++ LK K+LRERWL++G +
Sbjct: 2 AESSLYRQRLEVIAEKRRLQEEIRAARREVEEEKLRVERLKRKSLRERWLMDGAAAVPEP 61
Query: 66 GDEDLRRQMQDDE----QKTRLLEDSVSRLEKEIEVLE 99
++ + Q E + R LEDS+ L+ ++++L+
Sbjct: 62 SEDPTSKDPQSPEGQAQARIRNLEDSLFTLQSQLQLLQ 99
Score = 40.4 bits (93), Expect = 0.003
Identities = 84/368 (22%), Positives = 129/368 (35%), Gaps = 50/368 (13%)
Query: 57 EGTPSSASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAAPS 116
E P + EGD + E+ + + + V+ E+ E+L G P A S
Sbjct: 319 EDVPQGSPEGDG---QGGSGGEEGSFIWVERVTLSEEWEELLVEGLEGPEVAGRERGDES 375
Query: 117 PVRAPAPSPAKEERKTEVVMNSQQTPVGTPKDKRVSNTPLRTVDGSPMMKAAMYSVEITV 176
P+ A E E + +G +++ T + SP+++ ++ +
Sbjct: 376 PLGAEGAKTGGGEETWEAEKRKAEESMGIGSEEK-PGTGRDEAEMSPVVERKGGEKKLEL 434
Query: 177 EKDKVTGETRVLSSTTLLPRQPLPLGIKVYED--------------ETKVVHAVDGTAEN 222
E G L + +PL + KV E + V G +
Sbjct: 435 ES---RGSAEKLGTEREGGEEPLGIERKVEGHLRAEKEGDEEKRGAEEEEVEEPLGVEKK 491
Query: 223 G--IHPLSSSEVDELIHKADEVTLS---EAGSTAGAAETRGAVEGAARTTPSRREITGVQ 277
G P ++ E E K E TL G + E EG RE G +
Sbjct: 492 GGEEEPEATKEPLEAERKGGEETLEAEKRGGEESLETEKTQGTEGDLNLEQGSRE--GSE 549
Query: 278 AQPGEAT-SGPP------------GIQPGQEPPVTMIFMGYQNVEDEAETKKVLGLQDTI 324
+Q E +GPP G QP QE PV + + AE + LG +
Sbjct: 550 SQAEEMNEAGPPLEANTETRPEKEGPQP-QEKPVGALEEEGVKPQTAAEGQGPLGDATPL 608
Query: 325 TAELVVIEDAAEPKEPAPPNGSAAEP-----PTEAASREENQAGPEATTSDPQDLDMKKH 379
AE E AE + G +A P PT A +R Q P A T + K+
Sbjct: 609 LAETPAPEQPAECQPLLQGEGPSANPSAHPVPTYAPAR---QPEPSAPTEGEEASGPKQK 665
Query: 380 RCKCCSIM 387
C+CC++M
Sbjct: 666 TCQCCAVM 673
>gi|187761324 shootin1 isoform a [Homo sapiens]
Length = 631
Score = 57.0 bits (136), Expect = 3e-08
Identities = 82/384 (21%), Positives = 156/384 (40%), Gaps = 41/384 (10%)
Query: 3 VLAAETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQH-LKSKAL-RERWLLEGTP 60
+L + Q+ L+A+ E K ++E +R Q + + ++L+ L+++ L +E L+
Sbjct: 251 LLLQSSIPDQQLLKALDENAKLTQQLEEERIQHQQKVKELEEQLENETLHKEIHNLKQQL 310
Query: 61 SSASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAAPSPVRA 120
E ++L + Q+ E+K R L+ SV L+K + E P P P+
Sbjct: 311 ELLEEDKKELELKYQNSEEKARNLKHSVDELQKRVNQSENSVPPP------PPPPPPLPP 364
Query: 121 PAPSPAKEERKTEVVMNSQQTPVGTPKDKRVSNTPLRTVDGSPMMKAAMYSVEITVEKDK 180
P P+P R ++ + P G+ K + P T + + + + A VE +++ K
Sbjct: 365 PPPNPI---RSLMSMIRKRSHPSGSGAKKEKATQPETTEEVTDLKRQA---VEEMMDRIK 418
Query: 181 VTGETRVLSSTTLLPRQP-LPLGIKVYEDETKVVHAV--DGTAENGIHPL----SSSEVD 233
R ++ T +P G + DE K + T+ + L S +E++
Sbjct: 419 KGVHLRPVNQTARPKTKPESSKGCESAVDELKGILGTLNKSTSSRSLKSLDPENSETELE 478
Query: 234 ELIHKADEVTLSEAGSTAGAAETR--------GAVEGAARTTPSRREITGVQAQPGEATS 285
++ + +++ S G T G+V +T +++ + P
Sbjct: 479 RILRRRKVTAEADSSSPTGILATSESKSMPVLGSVSSVTKTALNKKTLEAEFNSP----- 533
Query: 286 GPPGIQPGQEP----PVTMIFMGYQNVEDEAETKKVLGLQDTITAELVVIEDAAEPKEPA 341
PP +PG+ P T + +Q KK + + AE VV+ D EP
Sbjct: 534 SPPTPEPGEGPRKLEGCTSSKVTFQPPSSIGCRKKYIDGEK--QAEPVVVLDPVSTHEPQ 591
Query: 342 PPNGSAAEPPTEAASREENQAGPE 365
+ A + PT+ +E + PE
Sbjct: 592 TKDQVAEKDPTQ-HKEDEGEIQPE 614
>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
Length = 841
Score = 54.3 bits (129), Expect = 2e-07
Identities = 48/206 (23%), Positives = 95/206 (46%), Gaps = 15/206 (7%)
Query: 6 AETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSASE 65
A TT ++E + +AEKR++ E +R+ E++ R+LQ + K +RE L + A
Sbjct: 591 AGTTDREEATRLLAEKRRQARE----QREREEQERRLQAERDKRMREEQLAREAEARAER 646
Query: 66 GDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAAPSPVRAPAPSP 125
E RR+ Q+ +K + ++ RL+K+ E E A + +
Sbjct: 647 EAEARRREEQEAREKAQAEQEEQERLQKQKEEAEARSREEAERQRLEREKHFQQQEQERQ 706
Query: 126 AKEERKTEVVMNSQQTPVGTPKDKRVSN---------TPLRTVDG-SP-MMKAAMYSVEI 174
+ +R E++ ++++ V K K+ S P++ V+ SP + K A+ E
Sbjct: 707 ERRKRLEEIMKRTRKSEVSETKQKQDSKEANANGSSPEPVKAVEARSPGLQKEAVQKEEP 766
Query: 175 TVEKDKVTGETRVLSSTTLLPRQPLP 200
++ + + ++ L ++ + QPLP
Sbjct: 767 IPQEPQWSLPSKELPASLVNGLQPLP 792
Score = 33.5 bits (75), Expect = 0.33
Identities = 19/47 (40%), Positives = 23/47 (48%), Gaps = 6/47 (12%)
Query: 109 KENAAAPSPVRAPAPSPAKEERKTEVVMNSQQTPVGTPKDKRVSNTP 155
KE+AA SP +PAPSP T +Q P TP D V +P
Sbjct: 537 KESAAPASPAPSPAPSP------TPAPPQKEQPPAETPTDAAVLTSP 577
Score = 28.9 bits (63), Expect = 8.2
Identities = 14/44 (31%), Positives = 20/44 (45%), Gaps = 2/44 (4%)
Query: 337 PKEPAPPNGSAAEPPTEAASREENQAGPEATTSDPQDLDMKKHR 380
P +P P G+ A P +EE + P A + P+D K R
Sbjct: 491 PPKPPSPRGTTASPKGRVRRKEEAKESPSA--AGPEDKSQSKRR 532
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 53.5 bits (127), Expect = 3e-07
Identities = 42/142 (29%), Positives = 72/142 (50%), Gaps = 12/142 (8%)
Query: 4 LAAETTSQQERL-QAIAEKRKRQAEIENKRRQLEDER--RQLQHLKSKALRERWLLEGTP 60
L AE +QQ+ L QA AEK+K +AE E +RR +E+ RQ + + + ++R L EGT
Sbjct: 1646 LQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTA 1705
Query: 61 SSASEGDED---LRRQMQDDEQKTRLLEDSVSRLEKEIEVLER------GDSAPATAKEN 111
+++ LR + + EQ+ +LLE+ ++RL++E + + A A+
Sbjct: 1706 QQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEME 1765
Query: 112 AAAPSPVRAPAPSPAKEERKTE 133
S RA S + E+ +
Sbjct: 1766 VLLASKARAEEESRSTSEKSKQ 1787
Score = 40.0 bits (92), Expect = 0.004
Identities = 32/99 (32%), Positives = 51/99 (51%), Gaps = 3/99 (3%)
Query: 1 MEVLAAETTSQQERLQAIAEKRKRQAEIENKR-RQLEDERRQLQHLKSKALRERWLL-EG 58
MEVL A +E ++ +EK K++ E E R R+L +E +L+ L +A R+R L E
Sbjct: 1764 MEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEED 1823
Query: 59 TPSSASEGDEDLRRQMQDDEQKTRL-LEDSVSRLEKEIE 96
+E + L ++ + TRL E ++ EKE E
Sbjct: 1824 AARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAE 1862
Score = 37.0 bits (84), Expect = 0.030
Identities = 42/150 (28%), Positives = 67/150 (44%), Gaps = 30/150 (20%)
Query: 6 AETTSQQER-----------LQAIAEKR-KRQAEIENKRRQLEDERRQLQHLKSKALRER 53
AE T+Q ER L+ AE+R ++QAE E R + E E + Q ++ALR R
Sbjct: 1586 AEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLR 1645
Query: 54 WLLEGTPSSAS-----------EGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGD 102
E S E + + RR+ + +EQ R E + LEK+ ++ E
Sbjct: 1646 LQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAE--- 1702
Query: 103 SAPATAKENAAAPSP-VRAPAPSPAKEERK 131
TA++ AA +R A + E+++
Sbjct: 1703 ---GTAQQRLAAEQELIRLRAETEQGEQQR 1729
Score = 37.0 bits (84), Expect = 0.030
Identities = 25/95 (26%), Positives = 50/95 (52%), Gaps = 5/95 (5%)
Query: 5 AAETTSQQERLQAIAEKRKRQAEIENKRRQLEDER--RQLQHLKSKALRERWLLEGTPSS 62
A E + + QA AEK +++AE E RR ++ RQ Q ++ + + E T
Sbjct: 2121 AEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQ 2180
Query: 63 ASEGDED---LRRQMQDDEQKTRLLEDSVSRLEKE 94
++ +++ LR Q+++ + + LL++ + RL+ E
Sbjct: 2181 KAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAE 2215
Score = 36.6 bits (83), Expect = 0.039
Identities = 30/112 (26%), Positives = 56/112 (50%), Gaps = 9/112 (8%)
Query: 5 AAETTSQQERLQAIAEKRKRQAEIENKR-RQLEDERRQLQHLKSKALRERWLLEGTPSSA 63
A E +Q+ + Q AE+ +RQ + E++R RQ E E +++A RE+ A
Sbjct: 1482 AEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREK-------QRA 1534
Query: 64 SEGDEDLRRQMQDDEQKTRLLE-DSVSRLEKEIEVLERGDSAPATAKENAAA 114
+ E+LR Q ++ E++ R E + +++ +E +R A +K + A
Sbjct: 1535 LQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFA 1586
Score = 35.8 bits (81), Expect = 0.067
Identities = 63/300 (21%), Positives = 115/300 (38%), Gaps = 28/300 (9%)
Query: 2 EVLAAETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPS 61
E LAA + + + +A ++++AE E RR EDE Q + L+ +A + + +E +
Sbjct: 1837 EKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLA 1896
Query: 62 SASE-GDEDLRRQ---MQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAAPSP 117
+ D +L RQ ++D ++ R +E+ + L+ E A A E
Sbjct: 1897 QLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFE------KAAAGKAELELELGR 1950
Query: 118 VRAPAPSPAKEERKTEVVMNSQQTPVGTPK------DKRVSNTPLRTVDGSPMMKAAMYS 171
+R+ A + + + E+ Q+ + ++RV + + + KAA+
Sbjct: 1951 IRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEE 2010
Query: 172 VE---ITVEKDKVTGETRVLSSTTLLPRQPLPLGIKVYEDETKVVHAVDG---------T 219
VE VE+ + E S L ++ +E AV
Sbjct: 2011 VERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQ 2070
Query: 220 AENGIHPLSSSEVDELIHKADEVTLSEAGSTAGAAETRGAVEGAARTTPSRREITGVQAQ 279
E + E + A+E + + AA++R VE A R S E +AQ
Sbjct: 2071 QEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQ 2130
Score = 35.4 bits (80), Expect = 0.088
Identities = 23/97 (23%), Positives = 47/97 (48%), Gaps = 3/97 (3%)
Query: 18 IAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSASEGDEDLRRQMQDD 77
+A+ ++ + E + +++Q+E ER++L +A R + E E+L++ Q
Sbjct: 2524 VAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAE---EGVRRKQEELQQLEQQR 2580
Query: 78 EQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAA 114
Q+ LL + RL +++++LE A E A
Sbjct: 2581 RQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTA 2617
Score = 31.2 bits (69), Expect = 1.7
Identities = 25/98 (25%), Positives = 47/98 (47%), Gaps = 5/98 (5%)
Query: 2 EVLAAETTS-QQERLQAIAEKRKRQAEIENKRRQLE----DERRQLQHLKSKALRERWLL 56
E L ET + QQ L +R+ IE ++ +LE DE + Q L+ + R++ +
Sbjct: 2482 EQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQM 2541
Query: 57 EGTPSSASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKE 94
E E+ RR+ + E+ R ++ + +LE++
Sbjct: 2542 EQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQ 2579
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 53.5 bits (127), Expect = 3e-07
Identities = 42/142 (29%), Positives = 72/142 (50%), Gaps = 12/142 (8%)
Query: 4 LAAETTSQQERL-QAIAEKRKRQAEIENKRRQLEDER--RQLQHLKSKALRERWLLEGTP 60
L AE +QQ+ L QA AEK+K +AE E +RR +E+ RQ + + + ++R L EGT
Sbjct: 1650 LQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTA 1709
Query: 61 SSASEGDED---LRRQMQDDEQKTRLLEDSVSRLEKEIEVLER------GDSAPATAKEN 111
+++ LR + + EQ+ +LLE+ ++RL++E + + A A+
Sbjct: 1710 QQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEME 1769
Query: 112 AAAPSPVRAPAPSPAKEERKTE 133
S RA S + E+ +
Sbjct: 1770 VLLASKARAEEESRSTSEKSKQ 1791
Score = 40.0 bits (92), Expect = 0.004
Identities = 32/99 (32%), Positives = 51/99 (51%), Gaps = 3/99 (3%)
Query: 1 MEVLAAETTSQQERLQAIAEKRKRQAEIENKR-RQLEDERRQLQHLKSKALRERWLL-EG 58
MEVL A +E ++ +EK K++ E E R R+L +E +L+ L +A R+R L E
Sbjct: 1768 MEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEED 1827
Query: 59 TPSSASEGDEDLRRQMQDDEQKTRL-LEDSVSRLEKEIE 96
+E + L ++ + TRL E ++ EKE E
Sbjct: 1828 AARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAE 1866
Score = 37.0 bits (84), Expect = 0.030
Identities = 42/150 (28%), Positives = 67/150 (44%), Gaps = 30/150 (20%)
Query: 6 AETTSQQER-----------LQAIAEKR-KRQAEIENKRRQLEDERRQLQHLKSKALRER 53
AE T+Q ER L+ AE+R ++QAE E R + E E + Q ++ALR R
Sbjct: 1590 AEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLR 1649
Query: 54 WLLEGTPSSAS-----------EGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGD 102
E S E + + RR+ + +EQ R E + LEK+ ++ E
Sbjct: 1650 LQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAE--- 1706
Query: 103 SAPATAKENAAAPSP-VRAPAPSPAKEERK 131
TA++ AA +R A + E+++
Sbjct: 1707 ---GTAQQRLAAEQELIRLRAETEQGEQQR 1733
Score = 37.0 bits (84), Expect = 0.030
Identities = 25/95 (26%), Positives = 50/95 (52%), Gaps = 5/95 (5%)
Query: 5 AAETTSQQERLQAIAEKRKRQAEIENKRRQLEDER--RQLQHLKSKALRERWLLEGTPSS 62
A E + + QA AEK +++AE E RR ++ RQ Q ++ + + E T
Sbjct: 2125 AEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQ 2184
Query: 63 ASEGDED---LRRQMQDDEQKTRLLEDSVSRLEKE 94
++ +++ LR Q+++ + + LL++ + RL+ E
Sbjct: 2185 KAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAE 2219
Score = 36.6 bits (83), Expect = 0.039
Identities = 30/112 (26%), Positives = 56/112 (50%), Gaps = 9/112 (8%)
Query: 5 AAETTSQQERLQAIAEKRKRQAEIENKR-RQLEDERRQLQHLKSKALRERWLLEGTPSSA 63
A E +Q+ + Q AE+ +RQ + E++R RQ E E +++A RE+ A
Sbjct: 1486 AEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREK-------QRA 1538
Query: 64 SEGDEDLRRQMQDDEQKTRLLE-DSVSRLEKEIEVLERGDSAPATAKENAAA 114
+ E+LR Q ++ E++ R E + +++ +E +R A +K + A
Sbjct: 1539 LQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFA 1590
Score = 35.8 bits (81), Expect = 0.067
Identities = 63/300 (21%), Positives = 115/300 (38%), Gaps = 28/300 (9%)
Query: 2 EVLAAETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPS 61
E LAA + + + +A ++++AE E RR EDE Q + L+ +A + + +E +
Sbjct: 1841 EKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLA 1900
Query: 62 SASE-GDEDLRRQ---MQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAAPSP 117
+ D +L RQ ++D ++ R +E+ + L+ E A A E
Sbjct: 1901 QLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFE------KAAAGKAELELELGR 1954
Query: 118 VRAPAPSPAKEERKTEVVMNSQQTPVGTPK------DKRVSNTPLRTVDGSPMMKAAMYS 171
+R+ A + + + E+ Q+ + ++RV + + + KAA+
Sbjct: 1955 IRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEE 2014
Query: 172 VE---ITVEKDKVTGETRVLSSTTLLPRQPLPLGIKVYEDETKVVHAVDG---------T 219
VE VE+ + E S L ++ +E AV
Sbjct: 2015 VERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQ 2074
Query: 220 AENGIHPLSSSEVDELIHKADEVTLSEAGSTAGAAETRGAVEGAARTTPSRREITGVQAQ 279
E + E + A+E + + AA++R VE A R S E +AQ
Sbjct: 2075 QEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQ 2134
Score = 35.4 bits (80), Expect = 0.088
Identities = 23/97 (23%), Positives = 47/97 (48%), Gaps = 3/97 (3%)
Query: 18 IAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSASEGDEDLRRQMQDD 77
+A+ ++ + E + +++Q+E ER++L +A R + E E+L++ Q
Sbjct: 2528 VAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAE---EGVRRKQEELQQLEQQR 2584
Query: 78 EQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAA 114
Q+ LL + RL +++++LE A E A
Sbjct: 2585 RQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTA 2621
Score = 31.2 bits (69), Expect = 1.7
Identities = 25/98 (25%), Positives = 47/98 (47%), Gaps = 5/98 (5%)
Query: 2 EVLAAETTS-QQERLQAIAEKRKRQAEIENKRRQLE----DERRQLQHLKSKALRERWLL 56
E L ET + QQ L +R+ IE ++ +LE DE + Q L+ + R++ +
Sbjct: 2486 EQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQM 2545
Query: 57 EGTPSSASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKE 94
E E+ RR+ + E+ R ++ + +LE++
Sbjct: 2546 EQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQ 2583
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 53.5 bits (127), Expect = 3e-07
Identities = 42/142 (29%), Positives = 72/142 (50%), Gaps = 12/142 (8%)
Query: 4 LAAETTSQQERL-QAIAEKRKRQAEIENKRRQLEDER--RQLQHLKSKALRERWLLEGTP 60
L AE +QQ+ L QA AEK+K +AE E +RR +E+ RQ + + + ++R L EGT
Sbjct: 1646 LQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTA 1705
Query: 61 SSASEGDED---LRRQMQDDEQKTRLLEDSVSRLEKEIEVLER------GDSAPATAKEN 111
+++ LR + + EQ+ +LLE+ ++RL++E + + A A+
Sbjct: 1706 QQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEME 1765
Query: 112 AAAPSPVRAPAPSPAKEERKTE 133
S RA S + E+ +
Sbjct: 1766 VLLASKARAEEESRSTSEKSKQ 1787
Score = 40.0 bits (92), Expect = 0.004
Identities = 32/99 (32%), Positives = 51/99 (51%), Gaps = 3/99 (3%)
Query: 1 MEVLAAETTSQQERLQAIAEKRKRQAEIENKR-RQLEDERRQLQHLKSKALRERWLL-EG 58
MEVL A +E ++ +EK K++ E E R R+L +E +L+ L +A R+R L E
Sbjct: 1764 MEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEED 1823
Query: 59 TPSSASEGDEDLRRQMQDDEQKTRL-LEDSVSRLEKEIE 96
+E + L ++ + TRL E ++ EKE E
Sbjct: 1824 AARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAE 1862
Score = 37.0 bits (84), Expect = 0.030
Identities = 42/150 (28%), Positives = 67/150 (44%), Gaps = 30/150 (20%)
Query: 6 AETTSQQER-----------LQAIAEKR-KRQAEIENKRRQLEDERRQLQHLKSKALRER 53
AE T+Q ER L+ AE+R ++QAE E R + E E + Q ++ALR R
Sbjct: 1586 AEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLR 1645
Query: 54 WLLEGTPSSAS-----------EGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGD 102
E S E + + RR+ + +EQ R E + LEK+ ++ E
Sbjct: 1646 LQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAE--- 1702
Query: 103 SAPATAKENAAAPSP-VRAPAPSPAKEERK 131
TA++ AA +R A + E+++
Sbjct: 1703 ---GTAQQRLAAEQELIRLRAETEQGEQQR 1729
Score = 37.0 bits (84), Expect = 0.030
Identities = 25/95 (26%), Positives = 50/95 (52%), Gaps = 5/95 (5%)
Query: 5 AAETTSQQERLQAIAEKRKRQAEIENKRRQLEDER--RQLQHLKSKALRERWLLEGTPSS 62
A E + + QA AEK +++AE E RR ++ RQ Q ++ + + E T
Sbjct: 2121 AEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQ 2180
Query: 63 ASEGDED---LRRQMQDDEQKTRLLEDSVSRLEKE 94
++ +++ LR Q+++ + + LL++ + RL+ E
Sbjct: 2181 KAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAE 2215
Score = 36.6 bits (83), Expect = 0.039
Identities = 30/112 (26%), Positives = 56/112 (50%), Gaps = 9/112 (8%)
Query: 5 AAETTSQQERLQAIAEKRKRQAEIENKR-RQLEDERRQLQHLKSKALRERWLLEGTPSSA 63
A E +Q+ + Q AE+ +RQ + E++R RQ E E +++A RE+ A
Sbjct: 1482 AEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREK-------QRA 1534
Query: 64 SEGDEDLRRQMQDDEQKTRLLE-DSVSRLEKEIEVLERGDSAPATAKENAAA 114
+ E+LR Q ++ E++ R E + +++ +E +R A +K + A
Sbjct: 1535 LQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFA 1586
Score = 35.8 bits (81), Expect = 0.067
Identities = 63/300 (21%), Positives = 115/300 (38%), Gaps = 28/300 (9%)
Query: 2 EVLAAETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPS 61
E LAA + + + +A ++++AE E RR EDE Q + L+ +A + + +E +
Sbjct: 1837 EKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLA 1896
Query: 62 SASE-GDEDLRRQ---MQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAAPSP 117
+ D +L RQ ++D ++ R +E+ + L+ E A A E
Sbjct: 1897 QLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFE------KAAAGKAELELELGR 1950
Query: 118 VRAPAPSPAKEERKTEVVMNSQQTPVGTPK------DKRVSNTPLRTVDGSPMMKAAMYS 171
+R+ A + + + E+ Q+ + ++RV + + + KAA+
Sbjct: 1951 IRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEE 2010
Query: 172 VE---ITVEKDKVTGETRVLSSTTLLPRQPLPLGIKVYEDETKVVHAVDG---------T 219
VE VE+ + E S L ++ +E AV
Sbjct: 2011 VERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQ 2070
Query: 220 AENGIHPLSSSEVDELIHKADEVTLSEAGSTAGAAETRGAVEGAARTTPSRREITGVQAQ 279
E + E + A+E + + AA++R VE A R S E +AQ
Sbjct: 2071 QEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQ 2130
Score = 35.4 bits (80), Expect = 0.088
Identities = 23/97 (23%), Positives = 47/97 (48%), Gaps = 3/97 (3%)
Query: 18 IAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSASEGDEDLRRQMQDD 77
+A+ ++ + E + +++Q+E ER++L +A R + E E+L++ Q
Sbjct: 2524 VAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAE---EGVRRKQEELQQLEQQR 2580
Query: 78 EQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAA 114
Q+ LL + RL +++++LE A E A
Sbjct: 2581 RQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTA 2617
Score = 31.2 bits (69), Expect = 1.7
Identities = 25/98 (25%), Positives = 47/98 (47%), Gaps = 5/98 (5%)
Query: 2 EVLAAETTS-QQERLQAIAEKRKRQAEIENKRRQLE----DERRQLQHLKSKALRERWLL 56
E L ET + QQ L +R+ IE ++ +LE DE + Q L+ + R++ +
Sbjct: 2482 EQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQM 2541
Query: 57 EGTPSSASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKE 94
E E+ RR+ + E+ R ++ + +LE++
Sbjct: 2542 EQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQ 2579
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 53.5 bits (127), Expect = 3e-07
Identities = 42/142 (29%), Positives = 72/142 (50%), Gaps = 12/142 (8%)
Query: 4 LAAETTSQQERL-QAIAEKRKRQAEIENKRRQLEDER--RQLQHLKSKALRERWLLEGTP 60
L AE +QQ+ L QA AEK+K +AE E +RR +E+ RQ + + + ++R L EGT
Sbjct: 1614 LQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTA 1673
Query: 61 SSASEGDED---LRRQMQDDEQKTRLLEDSVSRLEKEIEVLER------GDSAPATAKEN 111
+++ LR + + EQ+ +LLE+ ++RL++E + + A A+
Sbjct: 1674 QQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEME 1733
Query: 112 AAAPSPVRAPAPSPAKEERKTE 133
S RA S + E+ +
Sbjct: 1734 VLLASKARAEEESRSTSEKSKQ 1755
Score = 40.0 bits (92), Expect = 0.004
Identities = 32/99 (32%), Positives = 51/99 (51%), Gaps = 3/99 (3%)
Query: 1 MEVLAAETTSQQERLQAIAEKRKRQAEIENKR-RQLEDERRQLQHLKSKALRERWLL-EG 58
MEVL A +E ++ +EK K++ E E R R+L +E +L+ L +A R+R L E
Sbjct: 1732 MEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEED 1791
Query: 59 TPSSASEGDEDLRRQMQDDEQKTRL-LEDSVSRLEKEIE 96
+E + L ++ + TRL E ++ EKE E
Sbjct: 1792 AARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAE 1830
Score = 37.0 bits (84), Expect = 0.030
Identities = 42/150 (28%), Positives = 67/150 (44%), Gaps = 30/150 (20%)
Query: 6 AETTSQQER-----------LQAIAEKR-KRQAEIENKRRQLEDERRQLQHLKSKALRER 53
AE T+Q ER L+ AE+R ++QAE E R + E E + Q ++ALR R
Sbjct: 1554 AEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLR 1613
Query: 54 WLLEGTPSSAS-----------EGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGD 102
E S E + + RR+ + +EQ R E + LEK+ ++ E
Sbjct: 1614 LQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAE--- 1670
Query: 103 SAPATAKENAAAPSP-VRAPAPSPAKEERK 131
TA++ AA +R A + E+++
Sbjct: 1671 ---GTAQQRLAAEQELIRLRAETEQGEQQR 1697
Score = 37.0 bits (84), Expect = 0.030
Identities = 25/95 (26%), Positives = 50/95 (52%), Gaps = 5/95 (5%)
Query: 5 AAETTSQQERLQAIAEKRKRQAEIENKRRQLEDER--RQLQHLKSKALRERWLLEGTPSS 62
A E + + QA AEK +++AE E RR ++ RQ Q ++ + + E T
Sbjct: 2089 AEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQ 2148
Query: 63 ASEGDED---LRRQMQDDEQKTRLLEDSVSRLEKE 94
++ +++ LR Q+++ + + LL++ + RL+ E
Sbjct: 2149 KAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAE 2183
Score = 36.6 bits (83), Expect = 0.039
Identities = 30/112 (26%), Positives = 56/112 (50%), Gaps = 9/112 (8%)
Query: 5 AAETTSQQERLQAIAEKRKRQAEIENKR-RQLEDERRQLQHLKSKALRERWLLEGTPSSA 63
A E +Q+ + Q AE+ +RQ + E++R RQ E E +++A RE+ A
Sbjct: 1450 AEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREK-------QRA 1502
Query: 64 SEGDEDLRRQMQDDEQKTRLLE-DSVSRLEKEIEVLERGDSAPATAKENAAA 114
+ E+LR Q ++ E++ R E + +++ +E +R A +K + A
Sbjct: 1503 LQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFA 1554
Score = 35.8 bits (81), Expect = 0.067
Identities = 63/300 (21%), Positives = 115/300 (38%), Gaps = 28/300 (9%)
Query: 2 EVLAAETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPS 61
E LAA + + + +A ++++AE E RR EDE Q + L+ +A + + +E +
Sbjct: 1805 EKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLA 1864
Query: 62 SASE-GDEDLRRQ---MQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAAPSP 117
+ D +L RQ ++D ++ R +E+ + L+ E A A E
Sbjct: 1865 QLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFE------KAAAGKAELELELGR 1918
Query: 118 VRAPAPSPAKEERKTEVVMNSQQTPVGTPK------DKRVSNTPLRTVDGSPMMKAAMYS 171
+R+ A + + + E+ Q+ + ++RV + + + KAA+
Sbjct: 1919 IRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEE 1978
Query: 172 VE---ITVEKDKVTGETRVLSSTTLLPRQPLPLGIKVYEDETKVVHAVDG---------T 219
VE VE+ + E S L ++ +E AV
Sbjct: 1979 VERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQ 2038
Query: 220 AENGIHPLSSSEVDELIHKADEVTLSEAGSTAGAAETRGAVEGAARTTPSRREITGVQAQ 279
E + E + A+E + + AA++R VE A R S E +AQ
Sbjct: 2039 QEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQ 2098
Score = 35.4 bits (80), Expect = 0.088
Identities = 23/97 (23%), Positives = 47/97 (48%), Gaps = 3/97 (3%)
Query: 18 IAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSASEGDEDLRRQMQDD 77
+A+ ++ + E + +++Q+E ER++L +A R + E E+L++ Q
Sbjct: 2492 VAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAE---EGVRRKQEELQQLEQQR 2548
Query: 78 EQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAA 114
Q+ LL + RL +++++LE A E A
Sbjct: 2549 RQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTA 2585
Score = 31.2 bits (69), Expect = 1.7
Identities = 25/98 (25%), Positives = 47/98 (47%), Gaps = 5/98 (5%)
Query: 2 EVLAAETTS-QQERLQAIAEKRKRQAEIENKRRQLE----DERRQLQHLKSKALRERWLL 56
E L ET + QQ L +R+ IE ++ +LE DE + Q L+ + R++ +
Sbjct: 2450 EQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQM 2509
Query: 57 EGTPSSASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKE 94
E E+ RR+ + E+ R ++ + +LE++
Sbjct: 2510 EQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQ 2547
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 53.5 bits (127), Expect = 3e-07
Identities = 42/142 (29%), Positives = 72/142 (50%), Gaps = 12/142 (8%)
Query: 4 LAAETTSQQERL-QAIAEKRKRQAEIENKRRQLEDER--RQLQHLKSKALRERWLLEGTP 60
L AE +QQ+ L QA AEK+K +AE E +RR +E+ RQ + + + ++R L EGT
Sbjct: 1783 LQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTA 1842
Query: 61 SSASEGDED---LRRQMQDDEQKTRLLEDSVSRLEKEIEVLER------GDSAPATAKEN 111
+++ LR + + EQ+ +LLE+ ++RL++E + + A A+
Sbjct: 1843 QQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEME 1902
Query: 112 AAAPSPVRAPAPSPAKEERKTE 133
S RA S + E+ +
Sbjct: 1903 VLLASKARAEEESRSTSEKSKQ 1924
Score = 40.0 bits (92), Expect = 0.004
Identities = 32/99 (32%), Positives = 51/99 (51%), Gaps = 3/99 (3%)
Query: 1 MEVLAAETTSQQERLQAIAEKRKRQAEIENKR-RQLEDERRQLQHLKSKALRERWLL-EG 58
MEVL A +E ++ +EK K++ E E R R+L +E +L+ L +A R+R L E
Sbjct: 1901 MEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEED 1960
Query: 59 TPSSASEGDEDLRRQMQDDEQKTRL-LEDSVSRLEKEIE 96
+E + L ++ + TRL E ++ EKE E
Sbjct: 1961 AARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAE 1999
Score = 37.0 bits (84), Expect = 0.030
Identities = 42/150 (28%), Positives = 67/150 (44%), Gaps = 30/150 (20%)
Query: 6 AETTSQQER-----------LQAIAEKR-KRQAEIENKRRQLEDERRQLQHLKSKALRER 53
AE T+Q ER L+ AE+R ++QAE E R + E E + Q ++ALR R
Sbjct: 1723 AEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLR 1782
Query: 54 WLLEGTPSSAS-----------EGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGD 102
E S E + + RR+ + +EQ R E + LEK+ ++ E
Sbjct: 1783 LQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAE--- 1839
Query: 103 SAPATAKENAAAPSP-VRAPAPSPAKEERK 131
TA++ AA +R A + E+++
Sbjct: 1840 ---GTAQQRLAAEQELIRLRAETEQGEQQR 1866
Score = 37.0 bits (84), Expect = 0.030
Identities = 25/95 (26%), Positives = 50/95 (52%), Gaps = 5/95 (5%)
Query: 5 AAETTSQQERLQAIAEKRKRQAEIENKRRQLEDER--RQLQHLKSKALRERWLLEGTPSS 62
A E + + QA AEK +++AE E RR ++ RQ Q ++ + + E T
Sbjct: 2258 AEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQ 2317
Query: 63 ASEGDED---LRRQMQDDEQKTRLLEDSVSRLEKE 94
++ +++ LR Q+++ + + LL++ + RL+ E
Sbjct: 2318 KAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAE 2352
Score = 36.6 bits (83), Expect = 0.039
Identities = 30/112 (26%), Positives = 56/112 (50%), Gaps = 9/112 (8%)
Query: 5 AAETTSQQERLQAIAEKRKRQAEIENKR-RQLEDERRQLQHLKSKALRERWLLEGTPSSA 63
A E +Q+ + Q AE+ +RQ + E++R RQ E E +++A RE+ A
Sbjct: 1619 AEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREK-------QRA 1671
Query: 64 SEGDEDLRRQMQDDEQKTRLLE-DSVSRLEKEIEVLERGDSAPATAKENAAA 114
+ E+LR Q ++ E++ R E + +++ +E +R A +K + A
Sbjct: 1672 LQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFA 1723
Score = 35.8 bits (81), Expect = 0.067
Identities = 63/300 (21%), Positives = 115/300 (38%), Gaps = 28/300 (9%)
Query: 2 EVLAAETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPS 61
E LAA + + + +A ++++AE E RR EDE Q + L+ +A + + +E +
Sbjct: 1974 EKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLA 2033
Query: 62 SASE-GDEDLRRQ---MQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAAPSP 117
+ D +L RQ ++D ++ R +E+ + L+ E A A E
Sbjct: 2034 QLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFE------KAAAGKAELELELGR 2087
Query: 118 VRAPAPSPAKEERKTEVVMNSQQTPVGTPK------DKRVSNTPLRTVDGSPMMKAAMYS 171
+R+ A + + + E+ Q+ + ++RV + + + KAA+
Sbjct: 2088 IRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEE 2147
Query: 172 VE---ITVEKDKVTGETRVLSSTTLLPRQPLPLGIKVYEDETKVVHAVDG---------T 219
VE VE+ + E S L ++ +E AV
Sbjct: 2148 VERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQ 2207
Query: 220 AENGIHPLSSSEVDELIHKADEVTLSEAGSTAGAAETRGAVEGAARTTPSRREITGVQAQ 279
E + E + A+E + + AA++R VE A R S E +AQ
Sbjct: 2208 QEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQ 2267
Score = 35.4 bits (80), Expect = 0.088
Identities = 23/97 (23%), Positives = 47/97 (48%), Gaps = 3/97 (3%)
Query: 18 IAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSASEGDEDLRRQMQDD 77
+A+ ++ + E + +++Q+E ER++L +A R + E E+L++ Q
Sbjct: 2661 VAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAE---EGVRRKQEELQQLEQQR 2717
Query: 78 EQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAA 114
Q+ LL + RL +++++LE A E A
Sbjct: 2718 RQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTA 2754
Score = 31.2 bits (69), Expect = 1.7
Identities = 25/98 (25%), Positives = 47/98 (47%), Gaps = 5/98 (5%)
Query: 2 EVLAAETTS-QQERLQAIAEKRKRQAEIENKRRQLE----DERRQLQHLKSKALRERWLL 56
E L ET + QQ L +R+ IE ++ +LE DE + Q L+ + R++ +
Sbjct: 2619 EQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQM 2678
Query: 57 EGTPSSASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKE 94
E E+ RR+ + E+ R ++ + +LE++
Sbjct: 2679 EQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQ 2716
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 53.5 bits (127), Expect = 3e-07
Identities = 42/142 (29%), Positives = 72/142 (50%), Gaps = 12/142 (8%)
Query: 4 LAAETTSQQERL-QAIAEKRKRQAEIENKRRQLEDER--RQLQHLKSKALRERWLLEGTP 60
L AE +QQ+ L QA AEK+K +AE E +RR +E+ RQ + + + ++R L EGT
Sbjct: 1624 LQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTA 1683
Query: 61 SSASEGDED---LRRQMQDDEQKTRLLEDSVSRLEKEIEVLER------GDSAPATAKEN 111
+++ LR + + EQ+ +LLE+ ++RL++E + + A A+
Sbjct: 1684 QQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEME 1743
Query: 112 AAAPSPVRAPAPSPAKEERKTE 133
S RA S + E+ +
Sbjct: 1744 VLLASKARAEEESRSTSEKSKQ 1765
Score = 40.0 bits (92), Expect = 0.004
Identities = 32/99 (32%), Positives = 51/99 (51%), Gaps = 3/99 (3%)
Query: 1 MEVLAAETTSQQERLQAIAEKRKRQAEIENKR-RQLEDERRQLQHLKSKALRERWLL-EG 58
MEVL A +E ++ +EK K++ E E R R+L +E +L+ L +A R+R L E
Sbjct: 1742 MEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEED 1801
Query: 59 TPSSASEGDEDLRRQMQDDEQKTRL-LEDSVSRLEKEIE 96
+E + L ++ + TRL E ++ EKE E
Sbjct: 1802 AARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAE 1840
Score = 37.0 bits (84), Expect = 0.030
Identities = 42/150 (28%), Positives = 67/150 (44%), Gaps = 30/150 (20%)
Query: 6 AETTSQQER-----------LQAIAEKR-KRQAEIENKRRQLEDERRQLQHLKSKALRER 53
AE T+Q ER L+ AE+R ++QAE E R + E E + Q ++ALR R
Sbjct: 1564 AEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLR 1623
Query: 54 WLLEGTPSSAS-----------EGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGD 102
E S E + + RR+ + +EQ R E + LEK+ ++ E
Sbjct: 1624 LQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAE--- 1680
Query: 103 SAPATAKENAAAPSP-VRAPAPSPAKEERK 131
TA++ AA +R A + E+++
Sbjct: 1681 ---GTAQQRLAAEQELIRLRAETEQGEQQR 1707
Score = 37.0 bits (84), Expect = 0.030
Identities = 25/95 (26%), Positives = 50/95 (52%), Gaps = 5/95 (5%)
Query: 5 AAETTSQQERLQAIAEKRKRQAEIENKRRQLEDER--RQLQHLKSKALRERWLLEGTPSS 62
A E + + QA AEK +++AE E RR ++ RQ Q ++ + + E T
Sbjct: 2099 AEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQ 2158
Query: 63 ASEGDED---LRRQMQDDEQKTRLLEDSVSRLEKE 94
++ +++ LR Q+++ + + LL++ + RL+ E
Sbjct: 2159 KAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAE 2193
Score = 36.6 bits (83), Expect = 0.039
Identities = 30/112 (26%), Positives = 56/112 (50%), Gaps = 9/112 (8%)
Query: 5 AAETTSQQERLQAIAEKRKRQAEIENKR-RQLEDERRQLQHLKSKALRERWLLEGTPSSA 63
A E +Q+ + Q AE+ +RQ + E++R RQ E E +++A RE+ A
Sbjct: 1460 AEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREK-------QRA 1512
Query: 64 SEGDEDLRRQMQDDEQKTRLLE-DSVSRLEKEIEVLERGDSAPATAKENAAA 114
+ E+LR Q ++ E++ R E + +++ +E +R A +K + A
Sbjct: 1513 LQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFA 1564
Score = 35.8 bits (81), Expect = 0.067
Identities = 63/300 (21%), Positives = 115/300 (38%), Gaps = 28/300 (9%)
Query: 2 EVLAAETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPS 61
E LAA + + + +A ++++AE E RR EDE Q + L+ +A + + +E +
Sbjct: 1815 EKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLA 1874
Query: 62 SASE-GDEDLRRQ---MQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAAPSP 117
+ D +L RQ ++D ++ R +E+ + L+ E A A E
Sbjct: 1875 QLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFE------KAAAGKAELELELGR 1928
Query: 118 VRAPAPSPAKEERKTEVVMNSQQTPVGTPK------DKRVSNTPLRTVDGSPMMKAAMYS 171
+R+ A + + + E+ Q+ + ++RV + + + KAA+
Sbjct: 1929 IRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEE 1988
Query: 172 VE---ITVEKDKVTGETRVLSSTTLLPRQPLPLGIKVYEDETKVVHAVDG---------T 219
VE VE+ + E S L ++ +E AV
Sbjct: 1989 VERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQ 2048
Query: 220 AENGIHPLSSSEVDELIHKADEVTLSEAGSTAGAAETRGAVEGAARTTPSRREITGVQAQ 279
E + E + A+E + + AA++R VE A R S E +AQ
Sbjct: 2049 QEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQ 2108
Score = 35.4 bits (80), Expect = 0.088
Identities = 23/97 (23%), Positives = 47/97 (48%), Gaps = 3/97 (3%)
Query: 18 IAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSASEGDEDLRRQMQDD 77
+A+ ++ + E + +++Q+E ER++L +A R + E E+L++ Q
Sbjct: 2502 VAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAE---EGVRRKQEELQQLEQQR 2558
Query: 78 EQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAA 114
Q+ LL + RL +++++LE A E A
Sbjct: 2559 RQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTA 2595
Score = 31.2 bits (69), Expect = 1.7
Identities = 25/98 (25%), Positives = 47/98 (47%), Gaps = 5/98 (5%)
Query: 2 EVLAAETTS-QQERLQAIAEKRKRQAEIENKRRQLE----DERRQLQHLKSKALRERWLL 56
E L ET + QQ L +R+ IE ++ +LE DE + Q L+ + R++ +
Sbjct: 2460 EQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQM 2519
Query: 57 EGTPSSASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKE 94
E E+ RR+ + E+ R ++ + +LE++
Sbjct: 2520 EQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQ 2557
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 53.5 bits (127), Expect = 3e-07
Identities = 42/142 (29%), Positives = 72/142 (50%), Gaps = 12/142 (8%)
Query: 4 LAAETTSQQERL-QAIAEKRKRQAEIENKRRQLEDER--RQLQHLKSKALRERWLLEGTP 60
L AE +QQ+ L QA AEK+K +AE E +RR +E+ RQ + + + ++R L EGT
Sbjct: 1632 LQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTA 1691
Query: 61 SSASEGDED---LRRQMQDDEQKTRLLEDSVSRLEKEIEVLER------GDSAPATAKEN 111
+++ LR + + EQ+ +LLE+ ++RL++E + + A A+
Sbjct: 1692 QQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEME 1751
Query: 112 AAAPSPVRAPAPSPAKEERKTE 133
S RA S + E+ +
Sbjct: 1752 VLLASKARAEEESRSTSEKSKQ 1773
Score = 40.0 bits (92), Expect = 0.004
Identities = 32/99 (32%), Positives = 51/99 (51%), Gaps = 3/99 (3%)
Query: 1 MEVLAAETTSQQERLQAIAEKRKRQAEIENKR-RQLEDERRQLQHLKSKALRERWLL-EG 58
MEVL A +E ++ +EK K++ E E R R+L +E +L+ L +A R+R L E
Sbjct: 1750 MEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEED 1809
Query: 59 TPSSASEGDEDLRRQMQDDEQKTRL-LEDSVSRLEKEIE 96
+E + L ++ + TRL E ++ EKE E
Sbjct: 1810 AARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAE 1848
Score = 37.0 bits (84), Expect = 0.030
Identities = 42/150 (28%), Positives = 67/150 (44%), Gaps = 30/150 (20%)
Query: 6 AETTSQQER-----------LQAIAEKR-KRQAEIENKRRQLEDERRQLQHLKSKALRER 53
AE T+Q ER L+ AE+R ++QAE E R + E E + Q ++ALR R
Sbjct: 1572 AEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLR 1631
Query: 54 WLLEGTPSSAS-----------EGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGD 102
E S E + + RR+ + +EQ R E + LEK+ ++ E
Sbjct: 1632 LQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAE--- 1688
Query: 103 SAPATAKENAAAPSP-VRAPAPSPAKEERK 131
TA++ AA +R A + E+++
Sbjct: 1689 ---GTAQQRLAAEQELIRLRAETEQGEQQR 1715
Score = 37.0 bits (84), Expect = 0.030
Identities = 25/95 (26%), Positives = 50/95 (52%), Gaps = 5/95 (5%)
Query: 5 AAETTSQQERLQAIAEKRKRQAEIENKRRQLEDER--RQLQHLKSKALRERWLLEGTPSS 62
A E + + QA AEK +++AE E RR ++ RQ Q ++ + + E T
Sbjct: 2107 AEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQ 2166
Query: 63 ASEGDED---LRRQMQDDEQKTRLLEDSVSRLEKE 94
++ +++ LR Q+++ + + LL++ + RL+ E
Sbjct: 2167 KAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAE 2201
Score = 36.6 bits (83), Expect = 0.039
Identities = 30/112 (26%), Positives = 56/112 (50%), Gaps = 9/112 (8%)
Query: 5 AAETTSQQERLQAIAEKRKRQAEIENKR-RQLEDERRQLQHLKSKALRERWLLEGTPSSA 63
A E +Q+ + Q AE+ +RQ + E++R RQ E E +++A RE+ A
Sbjct: 1468 AEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREK-------QRA 1520
Query: 64 SEGDEDLRRQMQDDEQKTRLLE-DSVSRLEKEIEVLERGDSAPATAKENAAA 114
+ E+LR Q ++ E++ R E + +++ +E +R A +K + A
Sbjct: 1521 LQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFA 1572
Score = 35.8 bits (81), Expect = 0.067
Identities = 63/300 (21%), Positives = 115/300 (38%), Gaps = 28/300 (9%)
Query: 2 EVLAAETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPS 61
E LAA + + + +A ++++AE E RR EDE Q + L+ +A + + +E +
Sbjct: 1823 EKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLA 1882
Query: 62 SASE-GDEDLRRQ---MQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAAPSP 117
+ D +L RQ ++D ++ R +E+ + L+ E A A E
Sbjct: 1883 QLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFE------KAAAGKAELELELGR 1936
Query: 118 VRAPAPSPAKEERKTEVVMNSQQTPVGTPK------DKRVSNTPLRTVDGSPMMKAAMYS 171
+R+ A + + + E+ Q+ + ++RV + + + KAA+
Sbjct: 1937 IRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEE 1996
Query: 172 VE---ITVEKDKVTGETRVLSSTTLLPRQPLPLGIKVYEDETKVVHAVDG---------T 219
VE VE+ + E S L ++ +E AV
Sbjct: 1997 VERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQ 2056
Query: 220 AENGIHPLSSSEVDELIHKADEVTLSEAGSTAGAAETRGAVEGAARTTPSRREITGVQAQ 279
E + E + A+E + + AA++R VE A R S E +AQ
Sbjct: 2057 QEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQ 2116
Score = 35.4 bits (80), Expect = 0.088
Identities = 23/97 (23%), Positives = 47/97 (48%), Gaps = 3/97 (3%)
Query: 18 IAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSASEGDEDLRRQMQDD 77
+A+ ++ + E + +++Q+E ER++L +A R + E E+L++ Q
Sbjct: 2510 VAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAE---EGVRRKQEELQQLEQQR 2566
Query: 78 EQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAA 114
Q+ LL + RL +++++LE A E A
Sbjct: 2567 RQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTA 2603
Score = 31.2 bits (69), Expect = 1.7
Identities = 25/98 (25%), Positives = 47/98 (47%), Gaps = 5/98 (5%)
Query: 2 EVLAAETTS-QQERLQAIAEKRKRQAEIENKRRQLE----DERRQLQHLKSKALRERWLL 56
E L ET + QQ L +R+ IE ++ +LE DE + Q L+ + R++ +
Sbjct: 2468 EQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQM 2527
Query: 57 EGTPSSASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKE 94
E E+ RR+ + E+ R ++ + +LE++
Sbjct: 2528 EQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQ 2565
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 53.5 bits (127), Expect = 3e-07
Identities = 42/142 (29%), Positives = 72/142 (50%), Gaps = 12/142 (8%)
Query: 4 LAAETTSQQERL-QAIAEKRKRQAEIENKRRQLEDER--RQLQHLKSKALRERWLLEGTP 60
L AE +QQ+ L QA AEK+K +AE E +RR +E+ RQ + + + ++R L EGT
Sbjct: 1673 LQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTA 1732
Query: 61 SSASEGDED---LRRQMQDDEQKTRLLEDSVSRLEKEIEVLER------GDSAPATAKEN 111
+++ LR + + EQ+ +LLE+ ++RL++E + + A A+
Sbjct: 1733 QQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEME 1792
Query: 112 AAAPSPVRAPAPSPAKEERKTE 133
S RA S + E+ +
Sbjct: 1793 VLLASKARAEEESRSTSEKSKQ 1814
Score = 40.0 bits (92), Expect = 0.004
Identities = 32/99 (32%), Positives = 51/99 (51%), Gaps = 3/99 (3%)
Query: 1 MEVLAAETTSQQERLQAIAEKRKRQAEIENKR-RQLEDERRQLQHLKSKALRERWLL-EG 58
MEVL A +E ++ +EK K++ E E R R+L +E +L+ L +A R+R L E
Sbjct: 1791 MEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEED 1850
Query: 59 TPSSASEGDEDLRRQMQDDEQKTRL-LEDSVSRLEKEIE 96
+E + L ++ + TRL E ++ EKE E
Sbjct: 1851 AARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAE 1889
Score = 37.0 bits (84), Expect = 0.030
Identities = 42/150 (28%), Positives = 67/150 (44%), Gaps = 30/150 (20%)
Query: 6 AETTSQQER-----------LQAIAEKR-KRQAEIENKRRQLEDERRQLQHLKSKALRER 53
AE T+Q ER L+ AE+R ++QAE E R + E E + Q ++ALR R
Sbjct: 1613 AEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLR 1672
Query: 54 WLLEGTPSSAS-----------EGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGD 102
E S E + + RR+ + +EQ R E + LEK+ ++ E
Sbjct: 1673 LQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAE--- 1729
Query: 103 SAPATAKENAAAPSP-VRAPAPSPAKEERK 131
TA++ AA +R A + E+++
Sbjct: 1730 ---GTAQQRLAAEQELIRLRAETEQGEQQR 1756
Score = 37.0 bits (84), Expect = 0.030
Identities = 25/95 (26%), Positives = 50/95 (52%), Gaps = 5/95 (5%)
Query: 5 AAETTSQQERLQAIAEKRKRQAEIENKRRQLEDER--RQLQHLKSKALRERWLLEGTPSS 62
A E + + QA AEK +++AE E RR ++ RQ Q ++ + + E T
Sbjct: 2148 AEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQ 2207
Query: 63 ASEGDED---LRRQMQDDEQKTRLLEDSVSRLEKE 94
++ +++ LR Q+++ + + LL++ + RL+ E
Sbjct: 2208 KAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAE 2242
Score = 36.6 bits (83), Expect = 0.039
Identities = 30/112 (26%), Positives = 56/112 (50%), Gaps = 9/112 (8%)
Query: 5 AAETTSQQERLQAIAEKRKRQAEIENKR-RQLEDERRQLQHLKSKALRERWLLEGTPSSA 63
A E +Q+ + Q AE+ +RQ + E++R RQ E E +++A RE+ A
Sbjct: 1509 AEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREK-------QRA 1561
Query: 64 SEGDEDLRRQMQDDEQKTRLLE-DSVSRLEKEIEVLERGDSAPATAKENAAA 114
+ E+LR Q ++ E++ R E + +++ +E +R A +K + A
Sbjct: 1562 LQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFA 1613
Score = 35.8 bits (81), Expect = 0.067
Identities = 63/300 (21%), Positives = 115/300 (38%), Gaps = 28/300 (9%)
Query: 2 EVLAAETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPS 61
E LAA + + + +A ++++AE E RR EDE Q + L+ +A + + +E +
Sbjct: 1864 EKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLA 1923
Query: 62 SASE-GDEDLRRQ---MQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAAPSP 117
+ D +L RQ ++D ++ R +E+ + L+ E A A E
Sbjct: 1924 QLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFE------KAAAGKAELELELGR 1977
Query: 118 VRAPAPSPAKEERKTEVVMNSQQTPVGTPK------DKRVSNTPLRTVDGSPMMKAAMYS 171
+R+ A + + + E+ Q+ + ++RV + + + KAA+
Sbjct: 1978 IRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEE 2037
Query: 172 VE---ITVEKDKVTGETRVLSSTTLLPRQPLPLGIKVYEDETKVVHAVDG---------T 219
VE VE+ + E S L ++ +E AV
Sbjct: 2038 VERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQ 2097
Query: 220 AENGIHPLSSSEVDELIHKADEVTLSEAGSTAGAAETRGAVEGAARTTPSRREITGVQAQ 279
E + E + A+E + + AA++R VE A R S E +AQ
Sbjct: 2098 QEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQ 2157
Score = 35.4 bits (80), Expect = 0.088
Identities = 23/97 (23%), Positives = 47/97 (48%), Gaps = 3/97 (3%)
Query: 18 IAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSASEGDEDLRRQMQDD 77
+A+ ++ + E + +++Q+E ER++L +A R + E E+L++ Q
Sbjct: 2551 VAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAE---EGVRRKQEELQQLEQQR 2607
Query: 78 EQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAA 114
Q+ LL + RL +++++LE A E A
Sbjct: 2608 RQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTA 2644
Score = 31.2 bits (69), Expect = 1.7
Identities = 25/98 (25%), Positives = 47/98 (47%), Gaps = 5/98 (5%)
Query: 2 EVLAAETTS-QQERLQAIAEKRKRQAEIENKRRQLE----DERRQLQHLKSKALRERWLL 56
E L ET + QQ L +R+ IE ++ +LE DE + Q L+ + R++ +
Sbjct: 2509 EQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQM 2568
Query: 57 EGTPSSASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKE 94
E E+ RR+ + E+ R ++ + +LE++
Sbjct: 2569 EQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQ 2606
>gi|22035602 mitogen-activated protein kinase kinase kinase kinase 4
isoform 1 [Homo sapiens]
Length = 1166
Score = 50.1 bits (118), Expect = 3e-06
Identities = 80/392 (20%), Positives = 159/392 (40%), Gaps = 71/392 (18%)
Query: 2 EVLAAETTSQQE--RLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGT 59
++L + +QE + Q +AE++KR + + +RR+LE+++R+ + + + RE+ E
Sbjct: 374 QLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRRE-- 431
Query: 60 PSSASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERG---------------DSA 104
E+L R+ +++E++ R E+ R+E+E E + R
Sbjct: 432 -QEEKRRLEELERRRKEEEERRR-AEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLLQE 489
Query: 105 PATAKENAAAPSPVRAPAPSPAKEERKTEVVMNSQQTPVGTPKDKRVSNTPLRTVDGSPM 164
A + P P + P P ++ER + P D R P+RT SP+
Sbjct: 490 QAMLLHDHRRPHPQHSQQPPPPQQERSKPSFHAPEPKAHYEPAD-RAREVPVRTTSRSPV 548
Query: 165 MKAAMYSVEITVEKDKVTGETRVLSSTTLLPRQPLPLGIKVYEDETKVVHAVDGTAENGI 224
+ ++ + +++ G+ S++++ PR ++E K+V + +G
Sbjct: 549 LSRRDSPLQGSGQQNSQAGQRN--STSSIEPR-------LLWERVEKLVPRPGSGSSSGS 599
Query: 225 HPLSSSEVDELIHKADEVTLSEAGSTAGAAETRGAVEGAART--TPSRREITGVQAQPGE 282
S S GS +G+ E R V ++++ +PS+R V+ +P +
Sbjct: 600 SNSGSQPG------------SHPGSQSGSGE-RFRVRSSSKSEGSPSQRLENAVK-KPED 645
Query: 283 ATSGPPGIQPGQEPPVTMIFMGYQNVEDEAETKKVLGLQDTITAELVVIEDAAEPKEPAP 342
++P E +T + EL +ED P +
Sbjct: 646 KKEVFRPLKPAGEVDLT-----------------------ALAKELRAVEDVRPPHKVTD 682
Query: 343 PNGSAAEP-PTEAASREENQAGPEATTSDPQD 373
+ S+ E T+ + Q G + +TS P+D
Sbjct: 683 YSSSSEESGTTDEEDDDVEQEGADESTSGPED 714
Score = 40.8 bits (94), Expect = 0.002
Identities = 22/56 (39%), Positives = 36/56 (64%)
Query: 1 MEVLAAETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLL 56
+E L ++ER +A EKR+ + E E RRQLE+E+R L+ L+ + L+E+ +L
Sbjct: 438 LEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLLQEQAML 493
>gi|15826852 acyl-Coenzyme A binding domain containing 3 [Homo
sapiens]
Length = 528
Score = 47.0 bits (110), Expect = 3e-05
Identities = 38/127 (29%), Positives = 64/127 (50%), Gaps = 21/127 (16%)
Query: 11 QQERLQAIAEKRKRQAE-----IENKRRQLEDERRQLQHLKSK---ALRERWLLEGTPSS 62
++ERLQ EKR+R+ E E +RR++E+ER +L+ K + AL + ++ +
Sbjct: 203 ERERLQKEEEKRRREEEERLRREEEERRRIEEERLRLEQQKQQIMAALNSQTAVQFQQYA 262
Query: 63 AS------EGDEDLRRQMQDDEQKTRL-------LEDSVSRLEKEIEVLERGDSAPATAK 109
A E + L RQ+Q+ + + L + L+K+ EV+ G S P ++K
Sbjct: 263 AQQYPGNYEQQQILIRQLQEQHYQQYMQQLYQVQLAQQQAALQKQQEVVVAGSSLPTSSK 322
Query: 110 ENAAAPS 116
NA PS
Sbjct: 323 VNATVPS 329
Score = 35.0 bits (79), Expect = 0.11
Identities = 24/75 (32%), Positives = 40/75 (53%), Gaps = 17/75 (22%)
Query: 20 EKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSASEGDEDLRRQMQDDEQ 79
E+ K++ E E +RR+ E+ER +LQ + K RE +E LRR +E+
Sbjct: 185 EQEKKRKEEEERRRREEEERERLQKEEEKRRREE-------------EERLRR----EEE 227
Query: 80 KTRLLEDSVSRLEKE 94
+ R +E+ RLE++
Sbjct: 228 ERRRIEEERLRLEQQ 242
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 45.8 bits (107), Expect = 6e-05
Identities = 28/105 (26%), Positives = 53/105 (50%)
Query: 4 LAAETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSA 63
+A+ ++ Q+ + + E+ +++ + K RQLE+ER LQ + + + LE S+
Sbjct: 1310 VASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTL 1369
Query: 64 SEGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATA 108
+ D ++++QD LE+ R +KEIE L + A A
Sbjct: 1370 NIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAA 1414
Score = 35.8 bits (81), Expect = 0.067
Identities = 30/110 (27%), Positives = 56/110 (50%), Gaps = 10/110 (9%)
Query: 7 ETTSQQERLQA----IAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSS 62
+ T Q+E +QA + + ++RQ + EN+ ++LE + QL K+ L+E+ L+
Sbjct: 846 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKN-LLQEQ--LQAETEL 902
Query: 63 ASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENA 112
+E +E R ++ +L + +RLE+E +RG A K+ A
Sbjct: 903 YAEAEEMRVRLAAKKQELEEILHEMEARLEEE---EDRGQQLQAERKKMA 949
Score = 34.3 bits (77), Expect = 0.20
Identities = 27/118 (22%), Positives = 58/118 (49%), Gaps = 16/118 (13%)
Query: 2 EVLAAETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPS 61
E + E +Q +++ +K K+ EI Q+EDER+ + K +A
Sbjct: 1828 EQVEQEAREKQAATKSLKQKDKKLKEI---LLQVEDERKMAEQYKEQA-----------E 1873
Query: 62 SASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAAPSPVR 119
+ + L+RQ+++ E++++ + + +L++E++ E +S A +E A S +R
Sbjct: 1874 KGNARVKQLKRQLEEAEEESQRINANRRKLQRELD--EATESNEAMGREVNALKSKLR 1929
Score = 33.9 bits (76), Expect = 0.26
Identities = 24/82 (29%), Positives = 40/82 (48%), Gaps = 4/82 (4%)
Query: 14 RLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSASEGDEDL--- 70
R +AI + RK QA++++ +R+LED R + + A + + + EDL
Sbjct: 1640 REEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAA 1699
Query: 71 -RRQMQDDEQKTRLLEDSVSRL 91
R + Q D +K L E+ S L
Sbjct: 1700 ERARKQADLEKEELAEELASSL 1721
Score = 33.5 bits (75), Expect = 0.33
Identities = 23/90 (25%), Positives = 44/90 (48%), Gaps = 3/90 (3%)
Query: 21 KRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSASEGDEDLRRQMQDDEQK 80
KR + ++E + QLE+ +LQ + LR L + + + DL+ + + +E+K
Sbjct: 1534 KRALETQMEEMKTQLEELEDELQATEDAKLR---LEVNMQALKGQFERDLQARDEQNEEK 1590
Query: 81 TRLLEDSVSRLEKEIEVLERGDSAPATAKE 110
R L+ + E E+E + + A AK+
Sbjct: 1591 RRQLQRQLHEYETELEDERKQRALAAAAKK 1620
Score = 31.6 bits (70), Expect = 1.3
Identities = 19/84 (22%), Positives = 41/84 (48%)
Query: 16 QAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSASEGDEDLRRQMQ 75
+A+ E + + E+E + L+ E L K + LE + + E+++ Q++
Sbjct: 1490 RALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLE 1549
Query: 76 DDEQKTRLLEDSVSRLEKEIEVLE 99
+ E + + ED+ RLE ++ L+
Sbjct: 1550 ELEDELQATEDAKLRLEVNMQALK 1573
Score = 31.6 bits (70), Expect = 1.3
Identities = 33/137 (24%), Positives = 61/137 (44%), Gaps = 21/137 (15%)
Query: 2 EVLAAETTSQQERLQAIA-EKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLE--- 57
E LA E S A+ EKR+ +A I +LE+E+ ++ + + + E
Sbjct: 1711 EELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLS 1770
Query: 58 ---GTPSSASEGDEDLRRQM--QDDEQKTRLLE----------DSVSRLEKEIEVLERGD 102
T S ++ +E R+Q+ Q+ E +++L E +++ LE +I LE +
Sbjct: 1771 NELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLE--E 1828
Query: 103 SAPATAKENAAAPSPVR 119
A+E AA ++
Sbjct: 1829 QVEQEAREKQAATKSLK 1845
Score = 31.2 bits (69), Expect = 1.7
Identities = 29/112 (25%), Positives = 54/112 (48%), Gaps = 14/112 (12%)
Query: 2 EVLAAETT----SQQERLQAIAEKRKRQA---EIENKRRQLEDERRQLQHLKSKALRERW 54
E L AET +++ R++ A+K++ + E+E + + ED +QLQ + K ++
Sbjct: 894 EQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQML 953
Query: 55 LLEGTPSSASEGDEDLRRQMQDDEQKTRLLEDSV-------SRLEKEIEVLE 99
LE + L+ + E K + LED + ++L KE ++LE
Sbjct: 954 DLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLE 1005
Score = 30.8 bits (68), Expect = 2.2
Identities = 32/105 (30%), Positives = 49/105 (46%), Gaps = 12/105 (11%)
Query: 12 QERLQAIAEKRKR-QAEIENKRRQLEDERRQ---LQHLKSKALRERWLLEGTPSSASEGD 67
Q R + EKR++ Q ++ +LEDER+Q K K + LE SA +G
Sbjct: 1581 QARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGR 1640
Query: 68 EDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERG-DSAPATAKEN 111
E+ +Q+ R L+ + ++E+E D ATAKEN
Sbjct: 1641 EEAIKQL-------RKLQAQMKDFQRELEDARASRDEIFATAKEN 1678
Score = 29.3 bits (64), Expect = 6.3
Identities = 47/191 (24%), Positives = 80/191 (41%), Gaps = 18/191 (9%)
Query: 5 AAETTSQQERLQA-IAEKR----KRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGT 59
A++ Q LQA IAE + K++ E++ +L+DE Q K+ AL++ LEG
Sbjct: 1064 ASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQ----KNNALKKIRELEGH 1119
Query: 60 PSSASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAAPSPVR 119
S E + R E++ R L + + L+ E+E D+ +TA + R
Sbjct: 1120 ISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELE-----DTLDSTATQQELRAK--R 1172
Query: 120 APAPSPAKEERKTEVVMNSQQTPVGTPKDKRVSNTPLRTVDGSPMMKAAMYSVEITVEKD 179
+ K+ E + Q K + ++ KA + + T+EK+
Sbjct: 1173 EQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKE 1232
Query: 180 K--VTGETRVL 188
+ GE RVL
Sbjct: 1233 NADLAGELRVL 1243
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 45.8 bits (107), Expect = 6e-05
Identities = 28/105 (26%), Positives = 53/105 (50%)
Query: 4 LAAETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSA 63
+A+ ++ Q+ + + E+ +++ + K RQLE+ER LQ + + + LE S+
Sbjct: 1317 VASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTL 1376
Query: 64 SEGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATA 108
+ D ++++QD LE+ R +KEIE L + A A
Sbjct: 1377 NIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAA 1421
Score = 35.8 bits (81), Expect = 0.067
Identities = 30/110 (27%), Positives = 56/110 (50%), Gaps = 10/110 (9%)
Query: 7 ETTSQQERLQA----IAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSS 62
+ T Q+E +QA + + ++RQ + EN+ ++LE + QL K+ L+E+ L+
Sbjct: 853 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKN-LLQEQ--LQAETEL 909
Query: 63 ASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENA 112
+E +E R ++ +L + +RLE+E +RG A K+ A
Sbjct: 910 YAEAEEMRVRLAAKKQELEEILHEMEARLEEE---EDRGQQLQAERKKMA 956
Score = 34.3 bits (77), Expect = 0.20
Identities = 27/118 (22%), Positives = 58/118 (49%), Gaps = 16/118 (13%)
Query: 2 EVLAAETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPS 61
E + E +Q +++ +K K+ EI Q+EDER+ + K +A
Sbjct: 1835 EQVEQEAREKQAATKSLKQKDKKLKEI---LLQVEDERKMAEQYKEQA-----------E 1880
Query: 62 SASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAAPSPVR 119
+ + L+RQ+++ E++++ + + +L++E++ E +S A +E A S +R
Sbjct: 1881 KGNARVKQLKRQLEEAEEESQRINANRRKLQRELD--EATESNEAMGREVNALKSKLR 1936
Score = 33.9 bits (76), Expect = 0.26
Identities = 24/82 (29%), Positives = 40/82 (48%), Gaps = 4/82 (4%)
Query: 14 RLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSASEGDEDL--- 70
R +AI + RK QA++++ +R+LED R + + A + + + EDL
Sbjct: 1647 REEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAA 1706
Query: 71 -RRQMQDDEQKTRLLEDSVSRL 91
R + Q D +K L E+ S L
Sbjct: 1707 ERARKQADLEKEELAEELASSL 1728
Score = 33.5 bits (75), Expect = 0.33
Identities = 23/90 (25%), Positives = 44/90 (48%), Gaps = 3/90 (3%)
Query: 21 KRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSASEGDEDLRRQMQDDEQK 80
KR + ++E + QLE+ +LQ + LR L + + + DL+ + + +E+K
Sbjct: 1541 KRALETQMEEMKTQLEELEDELQATEDAKLR---LEVNMQALKGQFERDLQARDEQNEEK 1597
Query: 81 TRLLEDSVSRLEKEIEVLERGDSAPATAKE 110
R L+ + E E+E + + A AK+
Sbjct: 1598 RRQLQRQLHEYETELEDERKQRALAAAAKK 1627
Score = 31.6 bits (70), Expect = 1.3
Identities = 19/84 (22%), Positives = 41/84 (48%)
Query: 16 QAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSASEGDEDLRRQMQ 75
+A+ E + + E+E + L+ E L K + LE + + E+++ Q++
Sbjct: 1497 RALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLE 1556
Query: 76 DDEQKTRLLEDSVSRLEKEIEVLE 99
+ E + + ED+ RLE ++ L+
Sbjct: 1557 ELEDELQATEDAKLRLEVNMQALK 1580
Score = 31.6 bits (70), Expect = 1.3
Identities = 33/137 (24%), Positives = 61/137 (44%), Gaps = 21/137 (15%)
Query: 2 EVLAAETTSQQERLQAIA-EKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLE--- 57
E LA E S A+ EKR+ +A I +LE+E+ ++ + + + E
Sbjct: 1718 EELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLS 1777
Query: 58 ---GTPSSASEGDEDLRRQM--QDDEQKTRLLE----------DSVSRLEKEIEVLERGD 102
T S ++ +E R+Q+ Q+ E +++L E +++ LE +I LE +
Sbjct: 1778 NELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLE--E 1835
Query: 103 SAPATAKENAAAPSPVR 119
A+E AA ++
Sbjct: 1836 QVEQEAREKQAATKSLK 1852
Score = 31.2 bits (69), Expect = 1.7
Identities = 29/112 (25%), Positives = 54/112 (48%), Gaps = 14/112 (12%)
Query: 2 EVLAAETT----SQQERLQAIAEKRKRQA---EIENKRRQLEDERRQLQHLKSKALRERW 54
E L AET +++ R++ A+K++ + E+E + + ED +QLQ + K ++
Sbjct: 901 EQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQML 960
Query: 55 LLEGTPSSASEGDEDLRRQMQDDEQKTRLLEDSV-------SRLEKEIEVLE 99
LE + L+ + E K + LED + ++L KE ++LE
Sbjct: 961 DLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLE 1012
Score = 30.8 bits (68), Expect = 2.2
Identities = 32/105 (30%), Positives = 49/105 (46%), Gaps = 12/105 (11%)
Query: 12 QERLQAIAEKRKR-QAEIENKRRQLEDERRQ---LQHLKSKALRERWLLEGTPSSASEGD 67
Q R + EKR++ Q ++ +LEDER+Q K K + LE SA +G
Sbjct: 1588 QARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGR 1647
Query: 68 EDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERG-DSAPATAKEN 111
E+ +Q+ R L+ + ++E+E D ATAKEN
Sbjct: 1648 EEAIKQL-------RKLQAQMKDFQRELEDARASRDEIFATAKEN 1685
Score = 29.3 bits (64), Expect = 6.3
Identities = 47/191 (24%), Positives = 80/191 (41%), Gaps = 18/191 (9%)
Query: 5 AAETTSQQERLQA-IAEKR----KRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGT 59
A++ Q LQA IAE + K++ E++ +L+DE Q K+ AL++ LEG
Sbjct: 1071 ASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQ----KNNALKKIRELEGH 1126
Query: 60 PSSASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAAPSPVR 119
S E + R E++ R L + + L+ E+E D+ +TA + R
Sbjct: 1127 ISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELE-----DTLDSTATQQELRAK--R 1179
Query: 120 APAPSPAKEERKTEVVMNSQQTPVGTPKDKRVSNTPLRTVDGSPMMKAAMYSVEITVEKD 179
+ K+ E + Q K + ++ KA + + T+EK+
Sbjct: 1180 EQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKE 1239
Query: 180 K--VTGETRVL 188
+ GE RVL
Sbjct: 1240 NADLAGELRVL 1250
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 45.8 bits (107), Expect = 6e-05
Identities = 28/105 (26%), Positives = 53/105 (50%)
Query: 4 LAAETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSA 63
+A+ ++ Q+ + + E+ +++ + K RQLE+ER LQ + + + LE S+
Sbjct: 1317 VASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTL 1376
Query: 64 SEGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATA 108
+ D ++++QD LE+ R +KEIE L + A A
Sbjct: 1377 NIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAA 1421
Score = 39.7 bits (91), Expect = 0.005
Identities = 29/127 (22%), Positives = 61/127 (48%), Gaps = 16/127 (12%)
Query: 2 EVLAAETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPS 61
E + E +Q +++ +K K+ EI Q+EDER+ + K +A
Sbjct: 1835 EQVEQEAREKQAATKSLKQKDKKLKEI---LLQVEDERKMAEQYKEQA-----------E 1880
Query: 62 SASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAAPSPVRAP 121
+ + L+RQ+++ E++++ + + +L++E++ E +S A +E A S +R P
Sbjct: 1881 KGNARVKQLKRQLEEAEEESQRINANRRKLQRELD--EATESNEAMGREVNALKSKLRGP 1938
Query: 122 APSPAKE 128
P +
Sbjct: 1939 PPQETSQ 1945
Score = 35.8 bits (81), Expect = 0.067
Identities = 30/110 (27%), Positives = 56/110 (50%), Gaps = 10/110 (9%)
Query: 7 ETTSQQERLQA----IAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSS 62
+ T Q+E +QA + + ++RQ + EN+ ++LE + QL K+ L+E+ L+
Sbjct: 853 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKN-LLQEQ--LQAETEL 909
Query: 63 ASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENA 112
+E +E R ++ +L + +RLE+E +RG A K+ A
Sbjct: 910 YAEAEEMRVRLAAKKQELEEILHEMEARLEEE---EDRGQQLQAERKKMA 956
Score = 33.9 bits (76), Expect = 0.26
Identities = 24/82 (29%), Positives = 40/82 (48%), Gaps = 4/82 (4%)
Query: 14 RLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSASEGDEDL--- 70
R +AI + RK QA++++ +R+LED R + + A + + + EDL
Sbjct: 1647 REEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAA 1706
Query: 71 -RRQMQDDEQKTRLLEDSVSRL 91
R + Q D +K L E+ S L
Sbjct: 1707 ERARKQADLEKEELAEELASSL 1728
Score = 33.5 bits (75), Expect = 0.33
Identities = 23/90 (25%), Positives = 44/90 (48%), Gaps = 3/90 (3%)
Query: 21 KRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSASEGDEDLRRQMQDDEQK 80
KR + ++E + QLE+ +LQ + LR L + + + DL+ + + +E+K
Sbjct: 1541 KRALETQMEEMKTQLEELEDELQATEDAKLR---LEVNMQALKGQFERDLQARDEQNEEK 1597
Query: 81 TRLLEDSVSRLEKEIEVLERGDSAPATAKE 110
R L+ + E E+E + + A AK+
Sbjct: 1598 RRQLQRQLHEYETELEDERKQRALAAAAKK 1627
Score = 31.6 bits (70), Expect = 1.3
Identities = 19/84 (22%), Positives = 41/84 (48%)
Query: 16 QAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSASEGDEDLRRQMQ 75
+A+ E + + E+E + L+ E L K + LE + + E+++ Q++
Sbjct: 1497 RALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLE 1556
Query: 76 DDEQKTRLLEDSVSRLEKEIEVLE 99
+ E + + ED+ RLE ++ L+
Sbjct: 1557 ELEDELQATEDAKLRLEVNMQALK 1580
Score = 31.6 bits (70), Expect = 1.3
Identities = 33/137 (24%), Positives = 61/137 (44%), Gaps = 21/137 (15%)
Query: 2 EVLAAETTSQQERLQAIA-EKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLE--- 57
E LA E S A+ EKR+ +A I +LE+E+ ++ + + + E
Sbjct: 1718 EELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLS 1777
Query: 58 ---GTPSSASEGDEDLRRQM--QDDEQKTRLLE----------DSVSRLEKEIEVLERGD 102
T S ++ +E R+Q+ Q+ E +++L E +++ LE +I LE +
Sbjct: 1778 NELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLE--E 1835
Query: 103 SAPATAKENAAAPSPVR 119
A+E AA ++
Sbjct: 1836 QVEQEAREKQAATKSLK 1852
Score = 31.2 bits (69), Expect = 1.7
Identities = 29/112 (25%), Positives = 54/112 (48%), Gaps = 14/112 (12%)
Query: 2 EVLAAETT----SQQERLQAIAEKRKRQA---EIENKRRQLEDERRQLQHLKSKALRERW 54
E L AET +++ R++ A+K++ + E+E + + ED +QLQ + K ++
Sbjct: 901 EQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQML 960
Query: 55 LLEGTPSSASEGDEDLRRQMQDDEQKTRLLEDSV-------SRLEKEIEVLE 99
LE + L+ + E K + LED + ++L KE ++LE
Sbjct: 961 DLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLE 1012
Score = 30.8 bits (68), Expect = 2.2
Identities = 32/105 (30%), Positives = 49/105 (46%), Gaps = 12/105 (11%)
Query: 12 QERLQAIAEKRKR-QAEIENKRRQLEDERRQ---LQHLKSKALRERWLLEGTPSSASEGD 67
Q R + EKR++ Q ++ +LEDER+Q K K + LE SA +G
Sbjct: 1588 QARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGR 1647
Query: 68 EDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERG-DSAPATAKEN 111
E+ +Q+ R L+ + ++E+E D ATAKEN
Sbjct: 1648 EEAIKQL-------RKLQAQMKDFQRELEDARASRDEIFATAKEN 1685
Score = 29.3 bits (64), Expect = 6.3
Identities = 47/191 (24%), Positives = 80/191 (41%), Gaps = 18/191 (9%)
Query: 5 AAETTSQQERLQA-IAEKR----KRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGT 59
A++ Q LQA IAE + K++ E++ +L+DE Q K+ AL++ LEG
Sbjct: 1071 ASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQ----KNNALKKIRELEGH 1126
Query: 60 PSSASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAAPSPVR 119
S E + R E++ R L + + L+ E+E D+ +TA + R
Sbjct: 1127 ISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELE-----DTLDSTATQQELRAK--R 1179
Query: 120 APAPSPAKEERKTEVVMNSQQTPVGTPKDKRVSNTPLRTVDGSPMMKAAMYSVEITVEKD 179
+ K+ E + Q K + ++ KA + + T+EK+
Sbjct: 1180 EQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKE 1239
Query: 180 K--VTGETRVL 188
+ GE RVL
Sbjct: 1240 NADLAGELRVL 1250
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 45.8 bits (107), Expect = 6e-05
Identities = 28/105 (26%), Positives = 53/105 (50%)
Query: 4 LAAETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSA 63
+A+ ++ Q+ + + E+ +++ + K RQLE+ER LQ + + + LE S+
Sbjct: 1310 VASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTL 1369
Query: 64 SEGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATA 108
+ D ++++QD LE+ R +KEIE L + A A
Sbjct: 1370 NIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAA 1414
Score = 39.7 bits (91), Expect = 0.005
Identities = 29/127 (22%), Positives = 61/127 (48%), Gaps = 16/127 (12%)
Query: 2 EVLAAETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPS 61
E + E +Q +++ +K K+ EI Q+EDER+ + K +A
Sbjct: 1828 EQVEQEAREKQAATKSLKQKDKKLKEI---LLQVEDERKMAEQYKEQA-----------E 1873
Query: 62 SASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAAPSPVRAP 121
+ + L+RQ+++ E++++ + + +L++E++ E +S A +E A S +R P
Sbjct: 1874 KGNARVKQLKRQLEEAEEESQRINANRRKLQRELD--EATESNEAMGREVNALKSKLRGP 1931
Query: 122 APSPAKE 128
P +
Sbjct: 1932 PPQETSQ 1938
Score = 35.8 bits (81), Expect = 0.067
Identities = 30/110 (27%), Positives = 56/110 (50%), Gaps = 10/110 (9%)
Query: 7 ETTSQQERLQA----IAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSS 62
+ T Q+E +QA + + ++RQ + EN+ ++LE + QL K+ L+E+ L+
Sbjct: 846 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKN-LLQEQ--LQAETEL 902
Query: 63 ASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENA 112
+E +E R ++ +L + +RLE+E +RG A K+ A
Sbjct: 903 YAEAEEMRVRLAAKKQELEEILHEMEARLEEE---EDRGQQLQAERKKMA 949
Score = 33.9 bits (76), Expect = 0.26
Identities = 24/82 (29%), Positives = 40/82 (48%), Gaps = 4/82 (4%)
Query: 14 RLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSASEGDEDL--- 70
R +AI + RK QA++++ +R+LED R + + A + + + EDL
Sbjct: 1640 REEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAA 1699
Query: 71 -RRQMQDDEQKTRLLEDSVSRL 91
R + Q D +K L E+ S L
Sbjct: 1700 ERARKQADLEKEELAEELASSL 1721
Score = 33.5 bits (75), Expect = 0.33
Identities = 23/90 (25%), Positives = 44/90 (48%), Gaps = 3/90 (3%)
Query: 21 KRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSASEGDEDLRRQMQDDEQK 80
KR + ++E + QLE+ +LQ + LR L + + + DL+ + + +E+K
Sbjct: 1534 KRALETQMEEMKTQLEELEDELQATEDAKLR---LEVNMQALKGQFERDLQARDEQNEEK 1590
Query: 81 TRLLEDSVSRLEKEIEVLERGDSAPATAKE 110
R L+ + E E+E + + A AK+
Sbjct: 1591 RRQLQRQLHEYETELEDERKQRALAAAAKK 1620
Score = 31.6 bits (70), Expect = 1.3
Identities = 19/84 (22%), Positives = 41/84 (48%)
Query: 16 QAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSASEGDEDLRRQMQ 75
+A+ E + + E+E + L+ E L K + LE + + E+++ Q++
Sbjct: 1490 RALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLE 1549
Query: 76 DDEQKTRLLEDSVSRLEKEIEVLE 99
+ E + + ED+ RLE ++ L+
Sbjct: 1550 ELEDELQATEDAKLRLEVNMQALK 1573
Score = 31.6 bits (70), Expect = 1.3
Identities = 33/137 (24%), Positives = 61/137 (44%), Gaps = 21/137 (15%)
Query: 2 EVLAAETTSQQERLQAIA-EKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLE--- 57
E LA E S A+ EKR+ +A I +LE+E+ ++ + + + E
Sbjct: 1711 EELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLS 1770
Query: 58 ---GTPSSASEGDEDLRRQM--QDDEQKTRLLE----------DSVSRLEKEIEVLERGD 102
T S ++ +E R+Q+ Q+ E +++L E +++ LE +I LE +
Sbjct: 1771 NELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLE--E 1828
Query: 103 SAPATAKENAAAPSPVR 119
A+E AA ++
Sbjct: 1829 QVEQEAREKQAATKSLK 1845
Score = 31.2 bits (69), Expect = 1.7
Identities = 29/112 (25%), Positives = 54/112 (48%), Gaps = 14/112 (12%)
Query: 2 EVLAAETT----SQQERLQAIAEKRKRQA---EIENKRRQLEDERRQLQHLKSKALRERW 54
E L AET +++ R++ A+K++ + E+E + + ED +QLQ + K ++
Sbjct: 894 EQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQML 953
Query: 55 LLEGTPSSASEGDEDLRRQMQDDEQKTRLLEDSV-------SRLEKEIEVLE 99
LE + L+ + E K + LED + ++L KE ++LE
Sbjct: 954 DLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLE 1005
Score = 30.8 bits (68), Expect = 2.2
Identities = 32/105 (30%), Positives = 49/105 (46%), Gaps = 12/105 (11%)
Query: 12 QERLQAIAEKRKR-QAEIENKRRQLEDERRQ---LQHLKSKALRERWLLEGTPSSASEGD 67
Q R + EKR++ Q ++ +LEDER+Q K K + LE SA +G
Sbjct: 1581 QARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGR 1640
Query: 68 EDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERG-DSAPATAKEN 111
E+ +Q+ R L+ + ++E+E D ATAKEN
Sbjct: 1641 EEAIKQL-------RKLQAQMKDFQRELEDARASRDEIFATAKEN 1678
Score = 29.3 bits (64), Expect = 6.3
Identities = 47/191 (24%), Positives = 80/191 (41%), Gaps = 18/191 (9%)
Query: 5 AAETTSQQERLQA-IAEKR----KRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGT 59
A++ Q LQA IAE + K++ E++ +L+DE Q K+ AL++ LEG
Sbjct: 1064 ASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQ----KNNALKKIRELEGH 1119
Query: 60 PSSASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAAPSPVR 119
S E + R E++ R L + + L+ E+E D+ +TA + R
Sbjct: 1120 ISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELE-----DTLDSTATQQELRAK--R 1172
Query: 120 APAPSPAKEERKTEVVMNSQQTPVGTPKDKRVSNTPLRTVDGSPMMKAAMYSVEITVEKD 179
+ K+ E + Q K + ++ KA + + T+EK+
Sbjct: 1173 EQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKE 1232
Query: 180 K--VTGETRVL 188
+ GE RVL
Sbjct: 1233 NADLAGELRVL 1243
>gi|50511340 shootin1 isoform b [Homo sapiens]
Length = 456
Score = 45.8 bits (107), Expect = 6e-05
Identities = 40/178 (22%), Positives = 81/178 (45%), Gaps = 11/178 (6%)
Query: 3 VLAAETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQH-LKSKAL-RERWLLEGTP 60
+L + Q+ L+A+ E K ++E +R Q + + ++L+ L+++ L +E L+
Sbjct: 251 LLLQSSIPDQQLLKALDENAKLTQQLEEERIQHQQKVKELEEQLENETLHKEIHNLKQQL 310
Query: 61 SSASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAAPSPVRA 120
E ++L + Q+ E+K R L+ SV L+K + E P P P+
Sbjct: 311 ELLEEDKKELELKYQNSEEKARNLKHSVDELQKRVNQSENSVPPP------PPPPPPLPP 364
Query: 121 PAPSPAKEERKTEVVMNSQQTPVGTPKDKRVSNTPLRTVDGSPMMKAAMYSVEITVEK 178
P P+P R ++ + P G+ K + P T + + + + A+ + ++K
Sbjct: 365 PPPNPI---RSLMSMIRKRSHPSGSGAKKEKATQPETTEEVTDLKRQAVEEMMDRIKK 419
>gi|22035606 mitogen-activated protein kinase kinase kinase kinase 4
isoform 3 [Homo sapiens]
Length = 1212
Score = 45.4 bits (106), Expect = 8e-05
Identities = 82/386 (21%), Positives = 153/386 (39%), Gaps = 68/386 (17%)
Query: 1 MEVLAAETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLL---- 56
+E L ++ER +A EKR+ + E E RRQLE+E+R L+ L+ + L+E+ +L
Sbjct: 438 LEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLLQEQAMLLHDH 497
Query: 57 -----EGTPSSASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAP-ATAKE 110
+ + E + E K E + E E + S+P A +K+
Sbjct: 498 RRPHPQHSQQPPPPQQERSKPSFHAPEPKAH-YEPADRAREVEDRFRKTNHSSPEAQSKQ 556
Query: 111 NAAAPSPVRAPAPSPAKEERKTEVVMNSQQTPVGTPKDKRVSNTPLRTVDGSPMMKAAMY 170
P P P++ E + S + P + +V P+RT SP++
Sbjct: 557 TGRVLEP-----PVPSRSESFSNGNSESVHPALQRPAEPQV---PVRTTSRSPVLSRRDS 608
Query: 171 SVEITVEKDKVTGETRVLSSTTLLPRQPLPLGIKVYEDETKVVHAVDGTAENGIHPLSSS 230
++ + +++ G+ S++++ PR ++E K+V + +G S
Sbjct: 609 PLQGSGQQNSQAGQRN--STSSIEPR-------LLWERVEKLVPRPGSGSSSGSSNSGSQ 659
Query: 231 EVDELIHKADEVTLSEAGSTAGAAETRGAVEGAART--TPSRREITGVQAQPGEATSGPP 288
S GS +G+ E R V ++++ +PS+R V+ +P +
Sbjct: 660 PG------------SHPGSQSGSGE-RFRVRSSSKSEGSPSQRLENAVK-KPEDKKEVFR 705
Query: 289 GIQPGQEPPVTMIFMGYQNVEDEAETKKVLGLQDTITAELVVIEDAAEPKEPAPPNGSAA 348
++P E +T + EL +ED P + + S+
Sbjct: 706 PLKPAGEVDLT-----------------------ALAKELRAVEDVRPPHKVTDYSSSSE 742
Query: 349 EP-PTEAASREENQAGPEATTSDPQD 373
E T+ + Q G + +TS P+D
Sbjct: 743 ESGTTDEEDDDVEQEGADESTSGPED 768
>gi|239735588 TRAF2 and NCK interacting kinase isoform 6 [Homo
sapiens]
Length = 1297
Score = 44.7 bits (104), Expect = 1e-04
Identities = 59/285 (20%), Positives = 107/285 (37%), Gaps = 25/285 (8%)
Query: 12 QERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSASEGDEDLR 71
+E+++ E+R+ + E E RRQLE+E+RQL+ L+ + L E+ LL E R
Sbjct: 428 EEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLL----------EYKR 477
Query: 72 RQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAAPSPVRAPAPSPAKEERK 131
+Q+++ Q RL + + + + K+ +P+ PA +
Sbjct: 478 KQLEEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEI 537
Query: 132 TEVVMNSQQTPVGTPKDKRVSNTPLRTVDG-SPMMKAAMYSVEITVEKDKVTGETRVLSS 190
+V Q P T + V P + + G + + VE+ + T E
Sbjct: 538 PHLVAVKSQGPALT-ASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSE------ 590
Query: 191 TTLLPRQPLPLGIKVYEDETKVVHAVDGTAENGIHPLSSSEVDELIHKADEVTLSEAGST 250
PLP I+ ++ + + D + + ++S L K S G
Sbjct: 591 -----NPPLPTRIEKFDRSSWLRQEEDIPPK--VPQRTTSISPALARKNSPGNGSALGPR 643
Query: 251 AGAAETRGAVEGAARTTPSRREITGVQAQPGEATSGPPGIQPGQE 295
G+ R + RT P + ++S P QP +
Sbjct: 644 LGSQPIRASNPDLRRTEPILESPLQRTSSGSSSSSSTPSSQPSSQ 688
Score = 40.0 bits (92), Expect = 0.004
Identities = 21/86 (24%), Positives = 50/86 (58%), Gaps = 7/86 (8%)
Query: 10 SQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRER-------WLLEGTPSS 62
+++ + Q +AE++KR E + +RR+LE+++R+ + L+ + RE+ E
Sbjct: 380 NEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEERRR 439
Query: 63 ASEGDEDLRRQMQDDEQKTRLLEDSV 88
A E +RRQ+++++++ +L+ +
Sbjct: 440 AEHEQEYIRRQLEEEQRQLEILQQQL 465
>gi|239735586 TRAF2 and NCK interacting kinase isoform 5 [Homo
sapiens]
Length = 1305
Score = 44.7 bits (104), Expect = 1e-04
Identities = 59/285 (20%), Positives = 107/285 (37%), Gaps = 25/285 (8%)
Query: 12 QERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSASEGDEDLR 71
+E+++ E+R+ + E E RRQLE+E+RQL+ L+ + L E+ LL E R
Sbjct: 428 EEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLL----------EYKR 477
Query: 72 RQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAAPSPVRAPAPSPAKEERK 131
+Q+++ Q RL + + + + K+ +P+ PA +
Sbjct: 478 KQLEEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEI 537
Query: 132 TEVVMNSQQTPVGTPKDKRVSNTPLRTVDG-SPMMKAAMYSVEITVEKDKVTGETRVLSS 190
+V Q P T + V P + + G + + VE+ + T E
Sbjct: 538 PHLVAVKSQGPALT-ASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSE------ 590
Query: 191 TTLLPRQPLPLGIKVYEDETKVVHAVDGTAENGIHPLSSSEVDELIHKADEVTLSEAGST 250
PLP I+ ++ + + D + + ++S L K S G
Sbjct: 591 -----NPPLPTRIEKFDRSSWLRQEEDIPPK--VPQRTTSISPALARKNSPGNGSALGPR 643
Query: 251 AGAAETRGAVEGAARTTPSRREITGVQAQPGEATSGPPGIQPGQE 295
G+ R + RT P + ++S P QP +
Sbjct: 644 LGSQPIRASNPDLRRTEPILESPLQRTSSGSSSSSSTPSSQPSSQ 688
Score = 40.0 bits (92), Expect = 0.004
Identities = 21/86 (24%), Positives = 50/86 (58%), Gaps = 7/86 (8%)
Query: 10 SQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRER-------WLLEGTPSS 62
+++ + Q +AE++KR E + +RR+LE+++R+ + L+ + RE+ E
Sbjct: 380 NEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEERRR 439
Query: 63 ASEGDEDLRRQMQDDEQKTRLLEDSV 88
A E +RRQ+++++++ +L+ +
Sbjct: 440 AEHEQEYIRRQLEEEQRQLEILQQQL 465
>gi|56549694 enabled homolog isoform a [Homo sapiens]
Length = 591
Score = 44.3 bits (103), Expect = 2e-04
Identities = 51/212 (24%), Positives = 84/212 (39%), Gaps = 48/212 (22%)
Query: 1 MEVLAAETTS-----QQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWL 55
+EVL ++ T Q +L A + Q E+E +RRQL++++RQ + + + RER
Sbjct: 108 LEVLNSQETGPTLPRQNSQLPAQVQNGPSQEELEIQRRQLQEQQRQKELERERLERERME 167
Query: 56 LEGTPSSASEGD---------EDLRRQMQDDEQKTRL-----LE---------------- 85
E E + E L R+ Q+ E++ RL LE
Sbjct: 168 RERLERERLERERLERERLEQEQLERERQERERQERLERQERLERQERLERQERLDRERQ 227
Query: 86 -----DSVSRLEKEIEVLERGDSAPATAKE--------NAAAPSPVRAPAPSPAKEERKT 132
+ + RLE+E + ER + E +AAAP+ V P S + +
Sbjct: 228 ERQERERLERLERERQERERQEQLEREQLEWERERRISSAAAPASVETPLNSVLGDSSAS 287
Query: 133 EVVMNSQQTPVGTPKDKRVSNTPLRTVDGSPM 164
E + + P TP + + PL P+
Sbjct: 288 EPGLQAASQPAETPSQQGIVLGPLAPPPPPPL 319
>gi|39930375 enabled homolog isoform b [Homo sapiens]
Length = 570
Score = 44.3 bits (103), Expect = 2e-04
Identities = 51/212 (24%), Positives = 84/212 (39%), Gaps = 48/212 (22%)
Query: 1 MEVLAAETTS-----QQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWL 55
+EVL ++ T Q +L A + Q E+E +RRQL++++RQ + + + RER
Sbjct: 108 LEVLNSQETGPTLPRQNSQLPAQVQNGPSQEELEIQRRQLQEQQRQKELERERLERERME 167
Query: 56 LEGTPSSASEGD---------EDLRRQMQDDEQKTRL-----LE---------------- 85
E E + E L R+ Q+ E++ RL LE
Sbjct: 168 RERLERERLERERLERERLEQEQLERERQERERQERLERQERLERQERLERQERLDRERQ 227
Query: 86 -----DSVSRLEKEIEVLERGDSAPATAKE--------NAAAPSPVRAPAPSPAKEERKT 132
+ + RLE+E + ER + E +AAAP+ V P S + +
Sbjct: 228 ERQERERLERLERERQERERQEQLEREQLEWERERRISSAAAPASVETPLNSVLGDSSAS 287
Query: 133 EVVMNSQQTPVGTPKDKRVSNTPLRTVDGSPM 164
E + + P TP + + PL P+
Sbjct: 288 EPGLQAASQPAETPSQQGIVLGPLAPPPPPPL 319
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.306 0.123 0.334
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,112,263
Number of Sequences: 37866
Number of extensions: 853825
Number of successful extensions: 9161
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 191
Number of HSP's successfully gapped in prelim test: 691
Number of HSP's that attempted gapping in prelim test: 6265
Number of HSP's gapped (non-prelim): 2856
length of query: 387
length of database: 18,247,518
effective HSP length: 104
effective length of query: 283
effective length of database: 14,309,454
effective search space: 4049575482
effective search space used: 4049575482
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.