BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|93141029 paralemmin isoform 2 [Homo sapiens] (343 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|93141029 paralemmin isoform 2 [Homo sapiens] 672 0.0 gi|93141031 paralemmin isoform 1 [Homo sapiens] 651 0.0 gi|82617626 paralemmin 2 isoform b [Homo sapiens] 188 7e-48 gi|82524851 paralemmin 2 isoform a [Homo sapiens] 183 2e-46 gi|22325356 PALM2-AKAP2 protein isoform 2 [Homo sapiens] 109 3e-24 gi|6005709 PALM2-AKAP2 protein isoform 1 [Homo sapiens] 109 3e-24 gi|8923243 palmdelphin [Homo sapiens] 90 3e-18 gi|222537747 hypothetical protein LOC342979 [Homo sapiens] 70 2e-12 gi|22035602 mitogen-activated protein kinase kinase kinase kinas... 56 5e-08 gi|187761324 shootin1 isoform a [Homo sapiens] 54 2e-07 gi|41322923 plectin 1 isoform 11 [Homo sapiens] 54 3e-07 gi|41322914 plectin 1 isoform 10 [Homo sapiens] 54 3e-07 gi|41322919 plectin 1 isoform 8 [Homo sapiens] 54 3e-07 gi|41322910 plectin 1 isoform 7 [Homo sapiens] 54 3e-07 gi|41322916 plectin 1 isoform 6 [Homo sapiens] 54 3e-07 gi|41322908 plectin 1 isoform 3 [Homo sapiens] 54 3e-07 gi|41322912 plectin 1 isoform 2 [Homo sapiens] 54 3e-07 gi|47607492 plectin 1 isoform 1 [Homo sapiens] 54 3e-07 gi|78042577 MAP7 domain containing 1 [Homo sapiens] 54 3e-07 gi|22035606 mitogen-activated protein kinase kinase kinase kinas... 51 1e-06 gi|50511340 shootin1 isoform b [Homo sapiens] 49 5e-06 gi|15826852 acyl-Coenzyme A binding domain containing 3 [Homo sa... 47 2e-05 gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 47 3e-05 gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 47 3e-05 gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 47 3e-05 gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 47 3e-05 gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 46 6e-05 gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 46 6e-05 gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 46 6e-05 gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 46 6e-05 >gi|93141029 paralemmin isoform 2 [Homo sapiens] Length = 343 Score = 672 bits (1734), Expect = 0.0 Identities = 343/343 (100%), Positives = 343/343 (100%) Query: 1 MEVLAAETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTP 60 MEVLAAETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTP Sbjct: 1 MEVLAAETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTP 60 Query: 61 SSASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAAPSPVRA 120 SSASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAAPSPVRA Sbjct: 61 SSASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAAPSPVRA 120 Query: 121 PAPSPAKEERKTEVVMNSQQTPVGTPKDKRVSNTPLRTVDGSPMMKAVVHAVDGTAENGI 180 PAPSPAKEERKTEVVMNSQQTPVGTPKDKRVSNTPLRTVDGSPMMKAVVHAVDGTAENGI Sbjct: 121 PAPSPAKEERKTEVVMNSQQTPVGTPKDKRVSNTPLRTVDGSPMMKAVVHAVDGTAENGI 180 Query: 181 HPLSSSEVDELIHKADEVTLSEAGSTAGAAETRGAVEGAARTTPSRREITGVQAQPGEAT 240 HPLSSSEVDELIHKADEVTLSEAGSTAGAAETRGAVEGAARTTPSRREITGVQAQPGEAT Sbjct: 181 HPLSSSEVDELIHKADEVTLSEAGSTAGAAETRGAVEGAARTTPSRREITGVQAQPGEAT 240 Query: 241 SGPPGIQPGQEPPVTMIFMGYQNVEDEAETKKVLGLQDTITAELVVIEDAAEPKEPAPPN 300 SGPPGIQPGQEPPVTMIFMGYQNVEDEAETKKVLGLQDTITAELVVIEDAAEPKEPAPPN Sbjct: 241 SGPPGIQPGQEPPVTMIFMGYQNVEDEAETKKVLGLQDTITAELVVIEDAAEPKEPAPPN 300 Query: 301 GSAAEPPTEAASREENQAGPEATTSDPQDLDMKKHRCKCCSIM 343 GSAAEPPTEAASREENQAGPEATTSDPQDLDMKKHRCKCCSIM Sbjct: 301 GSAAEPPTEAASREENQAGPEATTSDPQDLDMKKHRCKCCSIM 343 >gi|93141031 paralemmin isoform 1 [Homo sapiens] Length = 387 Score = 651 bits (1679), Expect = 0.0 Identities = 343/387 (88%), Positives = 343/387 (88%), Gaps = 44/387 (11%) Query: 1 MEVLAAETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTP 60 MEVLAAETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTP Sbjct: 1 MEVLAAETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTP 60 Query: 61 SSASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAAPSPVRA 120 SSASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAAPSPVRA Sbjct: 61 SSASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAAPSPVRA 120 Query: 121 PAPSPAKEERKTEVVMNSQQTPVGTPKDKRVSNTPLRTVDGSPMMKA------------- 167 PAPSPAKEERKTEVVMNSQQTPVGTPKDKRVSNTPLRTVDGSPMMKA Sbjct: 121 PAPSPAKEERKTEVVMNSQQTPVGTPKDKRVSNTPLRTVDGSPMMKAAMYSVEITVEKDK 180 Query: 168 -------------------------------VVHAVDGTAENGIHPLSSSEVDELIHKAD 196 VVHAVDGTAENGIHPLSSSEVDELIHKAD Sbjct: 181 VTGETRVLSSTTLLPRQPLPLGIKVYEDETKVVHAVDGTAENGIHPLSSSEVDELIHKAD 240 Query: 197 EVTLSEAGSTAGAAETRGAVEGAARTTPSRREITGVQAQPGEATSGPPGIQPGQEPPVTM 256 EVTLSEAGSTAGAAETRGAVEGAARTTPSRREITGVQAQPGEATSGPPGIQPGQEPPVTM Sbjct: 241 EVTLSEAGSTAGAAETRGAVEGAARTTPSRREITGVQAQPGEATSGPPGIQPGQEPPVTM 300 Query: 257 IFMGYQNVEDEAETKKVLGLQDTITAELVVIEDAAEPKEPAPPNGSAAEPPTEAASREEN 316 IFMGYQNVEDEAETKKVLGLQDTITAELVVIEDAAEPKEPAPPNGSAAEPPTEAASREEN Sbjct: 301 IFMGYQNVEDEAETKKVLGLQDTITAELVVIEDAAEPKEPAPPNGSAAEPPTEAASREEN 360 Query: 317 QAGPEATTSDPQDLDMKKHRCKCCSIM 343 QAGPEATTSDPQDLDMKKHRCKCCSIM Sbjct: 361 QAGPEATTSDPQDLDMKKHRCKCCSIM 387 >gi|82617626 paralemmin 2 isoform b [Homo sapiens] Length = 379 Score = 188 bits (477), Expect = 7e-48 Identities = 133/389 (34%), Positives = 198/389 (50%), Gaps = 64/389 (16%) Query: 6 AETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSASE 65 AE +ERLQAIAEKRKRQ EIE KR+QL+++ LQH KSK LRE+WLL+G P+ +E Sbjct: 4 AEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAE 63 Query: 66 GDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKEN-------------- 111 +E RRQ ++DE + + LED++ RLE+EI+ LE + + +AKE Sbjct: 64 EEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLE-SEESQISAKEQIILEKLKETEKSFK 122 Query: 112 ------AAAPSPVRAPAPSPAKEER--KTEVVMNSQQTPVGTPKDKRVSNTPLRTVDGSP 163 ++ V A + K+++ +T+++ S P G V ++ D Sbjct: 123 DFQKGFSSTDGAVYAMEINVEKDKQTGETKILSTSTIGPEG------VHQKGVKVYDDGT 176 Query: 164 MMKAVVHAVDGTAENGIHPLSSSEVDELIHKADEVTLSEAGSTAGAAETRGAVEGAARTT 223 + V + ENG+H LS+ +V+ELI KA + +L G R + + + Sbjct: 177 KVVYEVRSGGTVVENGVHKLSTKDVEELIQKAGQSSLG-----GGHVSERTVIADGSLSH 231 Query: 224 PSRR------EITGVQAQPGEATSGPPGIQPGQEP-----------PVTMIFMGYQNVED 266 P ++ V + +SG PG Q Q P PVTMIFMGYQN+ED Sbjct: 232 PKEHMLCKEAKLEMVHKSRKDHSSGNPG-QQAQAPSAAGPEANLDQPVTMIFMGYQNIED 290 Query: 267 EAETKKVLGLQDTITAELVVIEDAAEPK-------EPAPPNGSAAE-----PPTEAASRE 314 E ETKKVLG +TI AELV+I++ E + + +G+AAE P ++ Sbjct: 291 EEETKKVLGYDETIKAELVLIDEDDEKSLREKTVTDVSTIDGNAAELVSGRPVSDTTEPS 350 Query: 315 ENQAGPEATTSDPQDLDMKKHRCKCCSIM 343 + E+ ++P KK RC+CC +M Sbjct: 351 SPEGKEESLATEPAPGTQKKKRCQCCVVM 379 >gi|82524851 paralemmin 2 isoform a [Homo sapiens] Length = 413 Score = 183 bits (465), Expect = 2e-46 Identities = 138/419 (32%), Positives = 198/419 (47%), Gaps = 90/419 (21%) Query: 6 AETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSASE 65 AE +ERLQAIAEKRKRQ EIE KR+QL+++ LQH KSK LRE+WLL+G P+ +E Sbjct: 4 AEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAE 63 Query: 66 GDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAAPS--------- 116 +E RRQ ++DE + + LED++ RLE+EI+ LE +S +AKE Sbjct: 64 EEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQ-ISAKEQIILEKLKETEKSFK 122 Query: 117 ------------------------PV---RAPAPSPAKEERKTEVVMNSQQTPVGTPKDK 149 P+ R PSP ++ + + + + KDK Sbjct: 123 DFQKGFSSTDGDAVNYISSQLPDLPILCSRTAEPSPGQDGTSRAAAVYAME--INVEKDK 180 Query: 150 RVSNTPLRTVDG----SPMMKAVVHAVDGT------------AENGIHPLSSSEVDELIH 193 + T + + K V DGT ENG+H LS+ +V+ELI Sbjct: 181 QTGETKILSTSTIGPEGVHQKGVKVYDDGTKVVYEVRSGGTVVENGVHKLSTKDVEELIQ 240 Query: 194 KADEVTLSEAGSTAGAAETRGAVEGAARTTPSRR------EITGVQAQPGEATSGPPGIQ 247 KA + +L G R + + + P ++ V + +SG PG Q Sbjct: 241 KAGQSSLG-----GGHVSERTVIADGSLSHPKEHMLCKEAKLEMVHKSRKDHSSGNPG-Q 294 Query: 248 PGQEP-----------PVTMIFMGYQNVEDEAETKKVLGLQDTITAELVVIEDAAEPK-- 294 Q P PVTMIFMGYQN+EDE ETKKVLG +TI AELV+I++ E Sbjct: 295 QAQAPSAAGPEANLDQPVTMIFMGYQNIEDEEETKKVLGYDETIKAELVLIDEDDEKSLR 354 Query: 295 -----EPAPPNGSAAE-----PPTEAASREENQAGPEATTSDPQDLDMKKHRCKCCSIM 343 + + +G+AAE P ++ + E+ ++P KK RC+CC +M Sbjct: 355 EKTVTDVSTIDGNAAELVSGRPVSDTTEPSSPEGKEESLATEPAPGTQKKKRCQCCVVM 413 >gi|22325356 PALM2-AKAP2 protein isoform 2 [Homo sapiens] Length = 1090 Score = 109 bits (273), Expect = 3e-24 Identities = 56/105 (53%), Positives = 77/105 (73%), Gaps = 1/105 (0%) Query: 6 AETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSASE 65 AE +ERLQAIAEKRKRQ EIE KR+QL+++ LQH KSK LRE+WLL+G P+ +E Sbjct: 2 AEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAE 61 Query: 66 GDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKE 110 +E RRQ ++DE + + LED++ RLE+EI+ LE + + +AKE Sbjct: 62 EEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLE-SEESQISAKE 105 >gi|6005709 PALM2-AKAP2 protein isoform 1 [Homo sapiens] Length = 1103 Score = 109 bits (273), Expect = 3e-24 Identities = 56/105 (53%), Positives = 77/105 (73%), Gaps = 1/105 (0%) Query: 6 AETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSASE 65 AE +ERLQAIAEKRKRQ EIE KR+QL+++ LQH KSK LRE+WLL+G P+ +E Sbjct: 2 AEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAE 61 Query: 66 GDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKE 110 +E RRQ ++DE + + LED++ RLE+EI+ LE + + +AKE Sbjct: 62 EEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLE-SEESQISAKE 105 >gi|8923243 palmdelphin [Homo sapiens] Length = 551 Score = 89.7 bits (221), Expect = 3e-18 Identities = 45/97 (46%), Positives = 70/97 (72%), Gaps = 2/97 (2%) Query: 14 RLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSASEGDEDLRRQ 73 RLQAI +KRK Q EI KR ++E+++ + QHLK KALRE+WLL+G S+ + E++++Q Sbjct: 10 RLQAITDKRKIQEEISQKRLKIEEDKLKHQHLKKKALREKWLLDGI--SSGKEQEEMKKQ 67 Query: 74 MQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKE 110 Q D+ + ++LE S+ RLEKEI+ LE+ + +T +E Sbjct: 68 NQQDQHQIQVLEQSILRLEKEIQDLEKAELQISTKEE 104 Score = 52.8 bits (125), Expect = 5e-07 Identities = 39/95 (41%), Positives = 47/95 (49%), Gaps = 15/95 (15%) Query: 243 PPGIQPGQEPPVTMIFMGYQNVEDEAETKKVL-GLQDTITAELVVIEDAAEPKE------ 295 PP I + PVTMIFMGYQ ED E KK L G I AELVVI+D E E Sbjct: 404 PPDINDTE--PVTMIFMGYQQAEDSEEDKKFLTGYDGIIHAELVVIDDEEEEDEGEAEKP 461 Query: 296 ---PAPPNGSAAEP--PTEAASREENQAGPEATTS 325 P P+ +P PT R+ ++A P T+ Sbjct: 462 SYHPIAPHSQVYQPAKPT-PLPRKRSEASPHENTN 495 >gi|222537747 hypothetical protein LOC342979 [Homo sapiens] Length = 673 Score = 70.5 bits (171), Expect = 2e-12 Identities = 35/98 (35%), Positives = 63/98 (64%), Gaps = 4/98 (4%) Query: 6 AETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSASE 65 AE++ ++RL+ IAEKR+ Q EI RR++E+E+ +++ LK K+LRERWL++G + Sbjct: 2 AESSLYRQRLEVIAEKRRLQEEIRAARREVEEEKLRVERLKRKSLRERWLMDGAAAVPEP 61 Query: 66 GDEDLRRQMQDDE----QKTRLLEDSVSRLEKEIEVLE 99 ++ + Q E + R LEDS+ L+ ++++L+ Sbjct: 62 SEDPTSKDPQSPEGQAQARIRNLEDSLFTLQSQLQLLQ 99 Score = 38.9 bits (89), Expect = 0.007 Identities = 51/183 (27%), Positives = 69/183 (37%), Gaps = 27/183 (14%) Query: 182 PLSSSEVDELIHKADEVTLS---EAGSTAGAAETRGAVEGAARTTPSRREITGVQAQPGE 238 P ++ E E K E TL G + E EG RE G ++Q E Sbjct: 497 PEATKEPLEAERKGGEETLEAEKRGGEESLETEKTQGTEGDLNLEQGSRE--GSESQAEE 554 Query: 239 AT-SGPP------------GIQPGQEPPVTMIFMGYQNVEDEAETKKVLGLQDTITAELV 285 +GPP G QP QE PV + + AE + LG + AE Sbjct: 555 MNEAGPPLEANTETRPEKEGPQP-QEKPVGALEEEGVKPQTAAEGQGPLGDATPLLAETP 613 Query: 286 VIEDAAEPKEPAPPNGSAAEP-----PTEAASREENQAGPEATTSDPQDLDMKKHRCKCC 340 E AE + G +A P PT A +R Q P A T + K+ C+CC Sbjct: 614 APEQPAECQPLLQGEGPSANPSAHPVPTYAPAR---QPEPSAPTEGEEASGPKQKTCQCC 670 Query: 341 SIM 343 ++M Sbjct: 671 AVM 673 >gi|22035602 mitogen-activated protein kinase kinase kinase kinase 4 isoform 1 [Homo sapiens] Length = 1166 Score = 55.8 bits (133), Expect = 5e-08 Identities = 77/355 (21%), Positives = 143/355 (40%), Gaps = 41/355 (11%) Query: 2 EVLAAETTSQQE--RLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGT 59 ++L + +QE + Q +AE++KR + + +RR+LE+++R+ + + + RE+ E Sbjct: 374 QLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRRE-- 431 Query: 60 PSSASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERG---------------DSA 104 E+L R+ +++E++ R E+ R+E+E E + R Sbjct: 432 -QEEKRRLEELERRRKEEEERRR-AEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLLQE 489 Query: 105 PATAKENAAAPSPVRAPAPSPAKEERKTEVVMNSQQTPVGTPKDKRVSNTPLRTVDGSPM 164 A + P P + P P ++ER + P D R P+RT SP+ Sbjct: 490 QAMLLHDHRRPHPQHSQQPPPPQQERSKPSFHAPEPKAHYEPAD-RAREVPVRTTSRSPV 548 Query: 165 MKAVVHAVDGTAEN----GIHPLSSSEVDELIHKADEVTLSEAGSTAGAAETRGAVEGAA 220 + + G+ + G +SS L+ + E + GS G+ G++ Sbjct: 549 LSRRDSPLQGSGQQNSQAGQRNSTSSIEPRLLWERVEKLVPRPGS--------GSSSGSS 600 Query: 221 RTTPSRREITGVQAQPGEATSGPPGIQPGQEPPVTMIFMGYQNVEDEAETKKVL---GLQ 277 + G Q+ GE + P + + ED+ E + L G Sbjct: 601 NSGSQPGSHPGSQSGSGERFR-VRSSSKSEGSPSQRLENAVKKPEDKKEVFRPLKPAGEV 659 Query: 278 D--TITAELVVIEDAAEPKEPAPPNGSAAEP-PTEAASREENQAGPEATTSDPQD 329 D + EL +ED P + + S+ E T+ + Q G + +TS P+D Sbjct: 660 DLTALAKELRAVEDVRPPHKVTDYSSSSEESGTTDEEDDDVEQEGADESTSGPED 714 >gi|187761324 shootin1 isoform a [Homo sapiens] Length = 631 Score = 53.9 bits (128), Expect = 2e-07 Identities = 71/350 (20%), Positives = 129/350 (36%), Gaps = 51/350 (14%) Query: 3 VLAAETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQH-LKSKAL-RERWLLEGTP 60 +L + Q+ L+A+ E K ++E +R Q + + ++L+ L+++ L +E L+ Sbjct: 251 LLLQSSIPDQQLLKALDENAKLTQQLEEERIQHQQKVKELEEQLENETLHKEIHNLKQQL 310 Query: 61 SSASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAAPSPVRA 120 E ++L + Q+ E+K R L+ SV L+K + E P P P+ Sbjct: 311 ELLEEDKKELELKYQNSEEKARNLKHSVDELQKRVNQSENSVPPP------PPPPPPLPP 364 Query: 121 PAPSPAKEERKTEVVMNSQQTPVGTPKDKRVSNTPLRTVDGSPMMKAVVHAVDGTAENGI 180 P P+P R ++ + P G+ K + P T + + + + V + + G+ Sbjct: 365 PPPNPI---RSLMSMIRKRSHPSGSGAKKEKATQPETTEEVTDLKRQAVEEMMDRIKKGV 421 Query: 181 HPLSSSEVDELIHKADEVTLSEAGSTAGAAETRGAVEGAARTTPSRREITGVQAQPGEA- 239 H ++ K + S G + E +G + G + S R + + + E Sbjct: 422 HLRPVNQTARPKTKPE----SSKGCESAVDELKG-ILGTLNKSTSSRSLKSLDPENSETE 476 Query: 240 ---------------TSGPPGIQPGQEPPVTMIFMGYQNVEDEAETKKVLGLQDTITAEL 284 +S P GI E + +V A KK L Sbjct: 477 LERILRRRKVTAEADSSSPTGILATSESKSMPVLGSVSSVTKTALNKKTL---------- 526 Query: 285 VVIEDAAEPKEPAPPNGSAAEPPTEAASREENQAGPEATTSDPQDLDMKK 334 AE P+PP E P + E + T P + +K Sbjct: 527 -----EAEFNSPSPPTPEPGEGPRKL----EGCTSSKVTFQPPSSIGCRK 567 >gi|41322923 plectin 1 isoform 11 [Homo sapiens] Length = 4547 Score = 53.5 bits (127), Expect = 3e-07 Identities = 42/142 (29%), Positives = 72/142 (50%), Gaps = 12/142 (8%) Query: 4 LAAETTSQQERL-QAIAEKRKRQAEIENKRRQLEDER--RQLQHLKSKALRERWLLEGTP 60 L AE +QQ+ L QA AEK+K +AE E +RR +E+ RQ + + + ++R L EGT Sbjct: 1646 LQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTA 1705 Query: 61 SSASEGDED---LRRQMQDDEQKTRLLEDSVSRLEKEIEVLER------GDSAPATAKEN 111 +++ LR + + EQ+ +LLE+ ++RL++E + + A A+ Sbjct: 1706 QQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEME 1765 Query: 112 AAAPSPVRAPAPSPAKEERKTE 133 S RA S + E+ + Sbjct: 1766 VLLASKARAEEESRSTSEKSKQ 1787 Score = 40.0 bits (92), Expect = 0.003 Identities = 32/99 (32%), Positives = 51/99 (51%), Gaps = 3/99 (3%) Query: 1 MEVLAAETTSQQERLQAIAEKRKRQAEIENKR-RQLEDERRQLQHLKSKALRERWLL-EG 58 MEVL A +E ++ +EK K++ E E R R+L +E +L+ L +A R+R L E Sbjct: 1764 MEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEED 1823 Query: 59 TPSSASEGDEDLRRQMQDDEQKTRL-LEDSVSRLEKEIE 96 +E + L ++ + TRL E ++ EKE E Sbjct: 1824 AARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAE 1862 Score = 37.0 bits (84), Expect = 0.026 Identities = 42/150 (28%), Positives = 67/150 (44%), Gaps = 30/150 (20%) Query: 6 AETTSQQER-----------LQAIAEKR-KRQAEIENKRRQLEDERRQLQHLKSKALRER 53 AE T+Q ER L+ AE+R ++QAE E R + E E + Q ++ALR R Sbjct: 1586 AEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLR 1645 Query: 54 WLLEGTPSSAS-----------EGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGD 102 E S E + + RR+ + +EQ R E + LEK+ ++ E Sbjct: 1646 LQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAE--- 1702 Query: 103 SAPATAKENAAAPSP-VRAPAPSPAKEERK 131 TA++ AA +R A + E+++ Sbjct: 1703 ---GTAQQRLAAEQELIRLRAETEQGEQQR 1729 Score = 37.0 bits (84), Expect = 0.026 Identities = 25/95 (26%), Positives = 50/95 (52%), Gaps = 5/95 (5%) Query: 5 AAETTSQQERLQAIAEKRKRQAEIENKRRQLEDER--RQLQHLKSKALRERWLLEGTPSS 62 A E + + QA AEK +++AE E RR ++ RQ Q ++ + + E T Sbjct: 2121 AEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQ 2180 Query: 63 ASEGDED---LRRQMQDDEQKTRLLEDSVSRLEKE 94 ++ +++ LR Q+++ + + LL++ + RL+ E Sbjct: 2181 KAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAE 2215 Score = 36.6 bits (83), Expect = 0.034 Identities = 30/112 (26%), Positives = 56/112 (50%), Gaps = 9/112 (8%) Query: 5 AAETTSQQERLQAIAEKRKRQAEIENKR-RQLEDERRQLQHLKSKALRERWLLEGTPSSA 63 A E +Q+ + Q AE+ +RQ + E++R RQ E E +++A RE+ A Sbjct: 1482 AEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREK-------QRA 1534 Query: 64 SEGDEDLRRQMQDDEQKTRLLE-DSVSRLEKEIEVLERGDSAPATAKENAAA 114 + E+LR Q ++ E++ R E + +++ +E +R A +K + A Sbjct: 1535 LQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFA 1586 Score = 35.4 bits (80), Expect = 0.075 Identities = 23/97 (23%), Positives = 47/97 (48%), Gaps = 3/97 (3%) Query: 18 IAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSASEGDEDLRRQMQDD 77 +A+ ++ + E + +++Q+E ER++L +A R + E E+L++ Q Sbjct: 2524 VAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAE---EGVRRKQEELQQLEQQR 2580 Query: 78 EQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAA 114 Q+ LL + RL +++++LE A E A Sbjct: 2581 RQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTA 2617 Score = 33.9 bits (76), Expect = 0.22 Identities = 73/355 (20%), Positives = 137/355 (38%), Gaps = 40/355 (11%) Query: 2 EVLAAETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPS 61 E LAA + + + +A ++++AE E RR EDE Q + L+ +A + + +E + Sbjct: 1837 EKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLA 1896 Query: 62 SASE-GDEDLRRQ---MQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAAPSP 117 + D +L RQ ++D ++ R +E+ + L+ E A A E Sbjct: 1897 QLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFE------KAAAGKAELELELGR 1950 Query: 118 VRAPAPSPAKEERKTEVVMNSQQTPVGTPKDKRVSNTPLRTVDGSPMMKAVVHAVDGTAE 177 +R+ A + + + E+ ++Q + +++R R + K++ + + Sbjct: 1951 IRSNAEDTLRSKEQAELEA-ARQRQLAAEEERRRREAEER------VQKSLAAEEEAARQ 2003 Query: 178 NGIHPLSSSEVDELIHKADEV-TLSEAGSTAGAAETRGAVEGAARTTPSRREITGVQAQP 236 + EV+ L K +E L E A + + A E A + + + Q Sbjct: 2004 ---RKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQ 2060 Query: 237 GEATSGPPGIQPGQEPPVTMIFMG----YQNVEDEAETKKVLGLQDTITAELVVIEDAAE 292 E +Q QE V G + +EAE +V ++ + V E+A Sbjct: 2061 KEQEL-QQTLQ--QEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQV-EEAER 2116 Query: 293 PKEPAPPNGSAAEPPTEAASREENQAGPEAT-----------TSDPQDLDMKKHR 336 K+ A A AA + +A EA D +M+KH+ Sbjct: 2117 LKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHK 2171 Score = 31.2 bits (69), Expect = 1.4 Identities = 25/98 (25%), Positives = 47/98 (47%), Gaps = 5/98 (5%) Query: 2 EVLAAETTS-QQERLQAIAEKRKRQAEIENKRRQLE----DERRQLQHLKSKALRERWLL 56 E L ET + QQ L +R+ IE ++ +LE DE + Q L+ + R++ + Sbjct: 2482 EQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQM 2541 Query: 57 EGTPSSASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKE 94 E E+ RR+ + E+ R ++ + +LE++ Sbjct: 2542 EQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQ 2579 >gi|41322914 plectin 1 isoform 10 [Homo sapiens] Length = 4551 Score = 53.5 bits (127), Expect = 3e-07 Identities = 42/142 (29%), Positives = 72/142 (50%), Gaps = 12/142 (8%) Query: 4 LAAETTSQQERL-QAIAEKRKRQAEIENKRRQLEDER--RQLQHLKSKALRERWLLEGTP 60 L AE +QQ+ L QA AEK+K +AE E +RR +E+ RQ + + + ++R L EGT Sbjct: 1650 LQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTA 1709 Query: 61 SSASEGDED---LRRQMQDDEQKTRLLEDSVSRLEKEIEVLER------GDSAPATAKEN 111 +++ LR + + EQ+ +LLE+ ++RL++E + + A A+ Sbjct: 1710 QQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEME 1769 Query: 112 AAAPSPVRAPAPSPAKEERKTE 133 S RA S + E+ + Sbjct: 1770 VLLASKARAEEESRSTSEKSKQ 1791 Score = 40.0 bits (92), Expect = 0.003 Identities = 32/99 (32%), Positives = 51/99 (51%), Gaps = 3/99 (3%) Query: 1 MEVLAAETTSQQERLQAIAEKRKRQAEIENKR-RQLEDERRQLQHLKSKALRERWLL-EG 58 MEVL A +E ++ +EK K++ E E R R+L +E +L+ L +A R+R L E Sbjct: 1768 MEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEED 1827 Query: 59 TPSSASEGDEDLRRQMQDDEQKTRL-LEDSVSRLEKEIE 96 +E + L ++ + TRL E ++ EKE E Sbjct: 1828 AARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAE 1866 Score = 37.0 bits (84), Expect = 0.026 Identities = 42/150 (28%), Positives = 67/150 (44%), Gaps = 30/150 (20%) Query: 6 AETTSQQER-----------LQAIAEKR-KRQAEIENKRRQLEDERRQLQHLKSKALRER 53 AE T+Q ER L+ AE+R ++QAE E R + E E + Q ++ALR R Sbjct: 1590 AEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLR 1649 Query: 54 WLLEGTPSSAS-----------EGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGD 102 E S E + + RR+ + +EQ R E + LEK+ ++ E Sbjct: 1650 LQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAE--- 1706 Query: 103 SAPATAKENAAAPSP-VRAPAPSPAKEERK 131 TA++ AA +R A + E+++ Sbjct: 1707 ---GTAQQRLAAEQELIRLRAETEQGEQQR 1733 Score = 37.0 bits (84), Expect = 0.026 Identities = 25/95 (26%), Positives = 50/95 (52%), Gaps = 5/95 (5%) Query: 5 AAETTSQQERLQAIAEKRKRQAEIENKRRQLEDER--RQLQHLKSKALRERWLLEGTPSS 62 A E + + QA AEK +++AE E RR ++ RQ Q ++ + + E T Sbjct: 2125 AEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQ 2184 Query: 63 ASEGDED---LRRQMQDDEQKTRLLEDSVSRLEKE 94 ++ +++ LR Q+++ + + LL++ + RL+ E Sbjct: 2185 KAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAE 2219 Score = 36.6 bits (83), Expect = 0.034 Identities = 30/112 (26%), Positives = 56/112 (50%), Gaps = 9/112 (8%) Query: 5 AAETTSQQERLQAIAEKRKRQAEIENKR-RQLEDERRQLQHLKSKALRERWLLEGTPSSA 63 A E +Q+ + Q AE+ +RQ + E++R RQ E E +++A RE+ A Sbjct: 1486 AEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREK-------QRA 1538 Query: 64 SEGDEDLRRQMQDDEQKTRLLE-DSVSRLEKEIEVLERGDSAPATAKENAAA 114 + E+LR Q ++ E++ R E + +++ +E +R A +K + A Sbjct: 1539 LQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFA 1590 Score = 35.4 bits (80), Expect = 0.075 Identities = 23/97 (23%), Positives = 47/97 (48%), Gaps = 3/97 (3%) Query: 18 IAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSASEGDEDLRRQMQDD 77 +A+ ++ + E + +++Q+E ER++L +A R + E E+L++ Q Sbjct: 2528 VAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAE---EGVRRKQEELQQLEQQR 2584 Query: 78 EQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAA 114 Q+ LL + RL +++++LE A E A Sbjct: 2585 RQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTA 2621 Score = 33.9 bits (76), Expect = 0.22 Identities = 73/355 (20%), Positives = 137/355 (38%), Gaps = 40/355 (11%) Query: 2 EVLAAETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPS 61 E LAA + + + +A ++++AE E RR EDE Q + L+ +A + + +E + Sbjct: 1841 EKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLA 1900 Query: 62 SASE-GDEDLRRQ---MQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAAPSP 117 + D +L RQ ++D ++ R +E+ + L+ E A A E Sbjct: 1901 QLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFE------KAAAGKAELELELGR 1954 Query: 118 VRAPAPSPAKEERKTEVVMNSQQTPVGTPKDKRVSNTPLRTVDGSPMMKAVVHAVDGTAE 177 +R+ A + + + E+ ++Q + +++R R + K++ + + Sbjct: 1955 IRSNAEDTLRSKEQAELEA-ARQRQLAAEEERRRREAEER------VQKSLAAEEEAARQ 2007 Query: 178 NGIHPLSSSEVDELIHKADEV-TLSEAGSTAGAAETRGAVEGAARTTPSRREITGVQAQP 236 + EV+ L K +E L E A + + A E A + + + Q Sbjct: 2008 ---RKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQ 2064 Query: 237 GEATSGPPGIQPGQEPPVTMIFMG----YQNVEDEAETKKVLGLQDTITAELVVIEDAAE 292 E +Q QE V G + +EAE +V ++ + V E+A Sbjct: 2065 KEQEL-QQTLQ--QEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQV-EEAER 2120 Query: 293 PKEPAPPNGSAAEPPTEAASREENQAGPEAT-----------TSDPQDLDMKKHR 336 K+ A A AA + +A EA D +M+KH+ Sbjct: 2121 LKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHK 2175 Score = 31.2 bits (69), Expect = 1.4 Identities = 25/98 (25%), Positives = 47/98 (47%), Gaps = 5/98 (5%) Query: 2 EVLAAETTS-QQERLQAIAEKRKRQAEIENKRRQLE----DERRQLQHLKSKALRERWLL 56 E L ET + QQ L +R+ IE ++ +LE DE + Q L+ + R++ + Sbjct: 2486 EQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQM 2545 Query: 57 EGTPSSASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKE 94 E E+ RR+ + E+ R ++ + +LE++ Sbjct: 2546 EQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQ 2583 >gi|41322919 plectin 1 isoform 8 [Homo sapiens] Length = 4547 Score = 53.5 bits (127), Expect = 3e-07 Identities = 42/142 (29%), Positives = 72/142 (50%), Gaps = 12/142 (8%) Query: 4 LAAETTSQQERL-QAIAEKRKRQAEIENKRRQLEDER--RQLQHLKSKALRERWLLEGTP 60 L AE +QQ+ L QA AEK+K +AE E +RR +E+ RQ + + + ++R L EGT Sbjct: 1646 LQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTA 1705 Query: 61 SSASEGDED---LRRQMQDDEQKTRLLEDSVSRLEKEIEVLER------GDSAPATAKEN 111 +++ LR + + EQ+ +LLE+ ++RL++E + + A A+ Sbjct: 1706 QQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEME 1765 Query: 112 AAAPSPVRAPAPSPAKEERKTE 133 S RA S + E+ + Sbjct: 1766 VLLASKARAEEESRSTSEKSKQ 1787 Score = 40.0 bits (92), Expect = 0.003 Identities = 32/99 (32%), Positives = 51/99 (51%), Gaps = 3/99 (3%) Query: 1 MEVLAAETTSQQERLQAIAEKRKRQAEIENKR-RQLEDERRQLQHLKSKALRERWLL-EG 58 MEVL A +E ++ +EK K++ E E R R+L +E +L+ L +A R+R L E Sbjct: 1764 MEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEED 1823 Query: 59 TPSSASEGDEDLRRQMQDDEQKTRL-LEDSVSRLEKEIE 96 +E + L ++ + TRL E ++ EKE E Sbjct: 1824 AARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAE 1862 Score = 37.0 bits (84), Expect = 0.026 Identities = 42/150 (28%), Positives = 67/150 (44%), Gaps = 30/150 (20%) Query: 6 AETTSQQER-----------LQAIAEKR-KRQAEIENKRRQLEDERRQLQHLKSKALRER 53 AE T+Q ER L+ AE+R ++QAE E R + E E + Q ++ALR R Sbjct: 1586 AEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLR 1645 Query: 54 WLLEGTPSSAS-----------EGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGD 102 E S E + + RR+ + +EQ R E + LEK+ ++ E Sbjct: 1646 LQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAE--- 1702 Query: 103 SAPATAKENAAAPSP-VRAPAPSPAKEERK 131 TA++ AA +R A + E+++ Sbjct: 1703 ---GTAQQRLAAEQELIRLRAETEQGEQQR 1729 Score = 37.0 bits (84), Expect = 0.026 Identities = 25/95 (26%), Positives = 50/95 (52%), Gaps = 5/95 (5%) Query: 5 AAETTSQQERLQAIAEKRKRQAEIENKRRQLEDER--RQLQHLKSKALRERWLLEGTPSS 62 A E + + QA AEK +++AE E RR ++ RQ Q ++ + + E T Sbjct: 2121 AEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQ 2180 Query: 63 ASEGDED---LRRQMQDDEQKTRLLEDSVSRLEKE 94 ++ +++ LR Q+++ + + LL++ + RL+ E Sbjct: 2181 KAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAE 2215 Score = 36.6 bits (83), Expect = 0.034 Identities = 30/112 (26%), Positives = 56/112 (50%), Gaps = 9/112 (8%) Query: 5 AAETTSQQERLQAIAEKRKRQAEIENKR-RQLEDERRQLQHLKSKALRERWLLEGTPSSA 63 A E +Q+ + Q AE+ +RQ + E++R RQ E E +++A RE+ A Sbjct: 1482 AEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREK-------QRA 1534 Query: 64 SEGDEDLRRQMQDDEQKTRLLE-DSVSRLEKEIEVLERGDSAPATAKENAAA 114 + E+LR Q ++ E++ R E + +++ +E +R A +K + A Sbjct: 1535 LQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFA 1586 Score = 35.4 bits (80), Expect = 0.075 Identities = 23/97 (23%), Positives = 47/97 (48%), Gaps = 3/97 (3%) Query: 18 IAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSASEGDEDLRRQMQDD 77 +A+ ++ + E + +++Q+E ER++L +A R + E E+L++ Q Sbjct: 2524 VAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAE---EGVRRKQEELQQLEQQR 2580 Query: 78 EQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAA 114 Q+ LL + RL +++++LE A E A Sbjct: 2581 RQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTA 2617 Score = 33.9 bits (76), Expect = 0.22 Identities = 73/355 (20%), Positives = 137/355 (38%), Gaps = 40/355 (11%) Query: 2 EVLAAETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPS 61 E LAA + + + +A ++++AE E RR EDE Q + L+ +A + + +E + Sbjct: 1837 EKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLA 1896 Query: 62 SASE-GDEDLRRQ---MQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAAPSP 117 + D +L RQ ++D ++ R +E+ + L+ E A A E Sbjct: 1897 QLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFE------KAAAGKAELELELGR 1950 Query: 118 VRAPAPSPAKEERKTEVVMNSQQTPVGTPKDKRVSNTPLRTVDGSPMMKAVVHAVDGTAE 177 +R+ A + + + E+ ++Q + +++R R + K++ + + Sbjct: 1951 IRSNAEDTLRSKEQAELEA-ARQRQLAAEEERRRREAEER------VQKSLAAEEEAARQ 2003 Query: 178 NGIHPLSSSEVDELIHKADEV-TLSEAGSTAGAAETRGAVEGAARTTPSRREITGVQAQP 236 + EV+ L K +E L E A + + A E A + + + Q Sbjct: 2004 ---RKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQ 2060 Query: 237 GEATSGPPGIQPGQEPPVTMIFMG----YQNVEDEAETKKVLGLQDTITAELVVIEDAAE 292 E +Q QE V G + +EAE +V ++ + V E+A Sbjct: 2061 KEQEL-QQTLQ--QEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQV-EEAER 2116 Query: 293 PKEPAPPNGSAAEPPTEAASREENQAGPEAT-----------TSDPQDLDMKKHR 336 K+ A A AA + +A EA D +M+KH+ Sbjct: 2117 LKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHK 2171 Score = 31.2 bits (69), Expect = 1.4 Identities = 25/98 (25%), Positives = 47/98 (47%), Gaps = 5/98 (5%) Query: 2 EVLAAETTS-QQERLQAIAEKRKRQAEIENKRRQLE----DERRQLQHLKSKALRERWLL 56 E L ET + QQ L +R+ IE ++ +LE DE + Q L+ + R++ + Sbjct: 2482 EQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQM 2541 Query: 57 EGTPSSASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKE 94 E E+ RR+ + E+ R ++ + +LE++ Sbjct: 2542 EQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQ 2579 >gi|41322910 plectin 1 isoform 7 [Homo sapiens] Length = 4515 Score = 53.5 bits (127), Expect = 3e-07 Identities = 42/142 (29%), Positives = 72/142 (50%), Gaps = 12/142 (8%) Query: 4 LAAETTSQQERL-QAIAEKRKRQAEIENKRRQLEDER--RQLQHLKSKALRERWLLEGTP 60 L AE +QQ+ L QA AEK+K +AE E +RR +E+ RQ + + + ++R L EGT Sbjct: 1614 LQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTA 1673 Query: 61 SSASEGDED---LRRQMQDDEQKTRLLEDSVSRLEKEIEVLER------GDSAPATAKEN 111 +++ LR + + EQ+ +LLE+ ++RL++E + + A A+ Sbjct: 1674 QQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEME 1733 Query: 112 AAAPSPVRAPAPSPAKEERKTE 133 S RA S + E+ + Sbjct: 1734 VLLASKARAEEESRSTSEKSKQ 1755 Score = 40.0 bits (92), Expect = 0.003 Identities = 32/99 (32%), Positives = 51/99 (51%), Gaps = 3/99 (3%) Query: 1 MEVLAAETTSQQERLQAIAEKRKRQAEIENKR-RQLEDERRQLQHLKSKALRERWLL-EG 58 MEVL A +E ++ +EK K++ E E R R+L +E +L+ L +A R+R L E Sbjct: 1732 MEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEED 1791 Query: 59 TPSSASEGDEDLRRQMQDDEQKTRL-LEDSVSRLEKEIE 96 +E + L ++ + TRL E ++ EKE E Sbjct: 1792 AARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAE 1830 Score = 37.0 bits (84), Expect = 0.026 Identities = 42/150 (28%), Positives = 67/150 (44%), Gaps = 30/150 (20%) Query: 6 AETTSQQER-----------LQAIAEKR-KRQAEIENKRRQLEDERRQLQHLKSKALRER 53 AE T+Q ER L+ AE+R ++QAE E R + E E + Q ++ALR R Sbjct: 1554 AEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLR 1613 Query: 54 WLLEGTPSSAS-----------EGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGD 102 E S E + + RR+ + +EQ R E + LEK+ ++ E Sbjct: 1614 LQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAE--- 1670 Query: 103 SAPATAKENAAAPSP-VRAPAPSPAKEERK 131 TA++ AA +R A + E+++ Sbjct: 1671 ---GTAQQRLAAEQELIRLRAETEQGEQQR 1697 Score = 37.0 bits (84), Expect = 0.026 Identities = 25/95 (26%), Positives = 50/95 (52%), Gaps = 5/95 (5%) Query: 5 AAETTSQQERLQAIAEKRKRQAEIENKRRQLEDER--RQLQHLKSKALRERWLLEGTPSS 62 A E + + QA AEK +++AE E RR ++ RQ Q ++ + + E T Sbjct: 2089 AEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQ 2148 Query: 63 ASEGDED---LRRQMQDDEQKTRLLEDSVSRLEKE 94 ++ +++ LR Q+++ + + LL++ + RL+ E Sbjct: 2149 KAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAE 2183 Score = 36.6 bits (83), Expect = 0.034 Identities = 30/112 (26%), Positives = 56/112 (50%), Gaps = 9/112 (8%) Query: 5 AAETTSQQERLQAIAEKRKRQAEIENKR-RQLEDERRQLQHLKSKALRERWLLEGTPSSA 63 A E +Q+ + Q AE+ +RQ + E++R RQ E E +++A RE+ A Sbjct: 1450 AEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREK-------QRA 1502 Query: 64 SEGDEDLRRQMQDDEQKTRLLE-DSVSRLEKEIEVLERGDSAPATAKENAAA 114 + E+LR Q ++ E++ R E + +++ +E +R A +K + A Sbjct: 1503 LQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFA 1554 Score = 35.4 bits (80), Expect = 0.075 Identities = 23/97 (23%), Positives = 47/97 (48%), Gaps = 3/97 (3%) Query: 18 IAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSASEGDEDLRRQMQDD 77 +A+ ++ + E + +++Q+E ER++L +A R + E E+L++ Q Sbjct: 2492 VAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAE---EGVRRKQEELQQLEQQR 2548 Query: 78 EQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAA 114 Q+ LL + RL +++++LE A E A Sbjct: 2549 RQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTA 2585 Score = 33.9 bits (76), Expect = 0.22 Identities = 73/355 (20%), Positives = 137/355 (38%), Gaps = 40/355 (11%) Query: 2 EVLAAETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPS 61 E LAA + + + +A ++++AE E RR EDE Q + L+ +A + + +E + Sbjct: 1805 EKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLA 1864 Query: 62 SASE-GDEDLRRQ---MQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAAPSP 117 + D +L RQ ++D ++ R +E+ + L+ E A A E Sbjct: 1865 QLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFE------KAAAGKAELELELGR 1918 Query: 118 VRAPAPSPAKEERKTEVVMNSQQTPVGTPKDKRVSNTPLRTVDGSPMMKAVVHAVDGTAE 177 +R+ A + + + E+ ++Q + +++R R + K++ + + Sbjct: 1919 IRSNAEDTLRSKEQAELEA-ARQRQLAAEEERRRREAEER------VQKSLAAEEEAARQ 1971 Query: 178 NGIHPLSSSEVDELIHKADEV-TLSEAGSTAGAAETRGAVEGAARTTPSRREITGVQAQP 236 + EV+ L K +E L E A + + A E A + + + Q Sbjct: 1972 ---RKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQ 2028 Query: 237 GEATSGPPGIQPGQEPPVTMIFMG----YQNVEDEAETKKVLGLQDTITAELVVIEDAAE 292 E +Q QE V G + +EAE +V ++ + V E+A Sbjct: 2029 KEQEL-QQTLQ--QEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQV-EEAER 2084 Query: 293 PKEPAPPNGSAAEPPTEAASREENQAGPEAT-----------TSDPQDLDMKKHR 336 K+ A A AA + +A EA D +M+KH+ Sbjct: 2085 LKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHK 2139 Score = 31.2 bits (69), Expect = 1.4 Identities = 25/98 (25%), Positives = 47/98 (47%), Gaps = 5/98 (5%) Query: 2 EVLAAETTS-QQERLQAIAEKRKRQAEIENKRRQLE----DERRQLQHLKSKALRERWLL 56 E L ET + QQ L +R+ IE ++ +LE DE + Q L+ + R++ + Sbjct: 2450 EQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQM 2509 Query: 57 EGTPSSASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKE 94 E E+ RR+ + E+ R ++ + +LE++ Sbjct: 2510 EQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQ 2547 >gi|41322916 plectin 1 isoform 6 [Homo sapiens] Length = 4684 Score = 53.5 bits (127), Expect = 3e-07 Identities = 42/142 (29%), Positives = 72/142 (50%), Gaps = 12/142 (8%) Query: 4 LAAETTSQQERL-QAIAEKRKRQAEIENKRRQLEDER--RQLQHLKSKALRERWLLEGTP 60 L AE +QQ+ L QA AEK+K +AE E +RR +E+ RQ + + + ++R L EGT Sbjct: 1783 LQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTA 1842 Query: 61 SSASEGDED---LRRQMQDDEQKTRLLEDSVSRLEKEIEVLER------GDSAPATAKEN 111 +++ LR + + EQ+ +LLE+ ++RL++E + + A A+ Sbjct: 1843 QQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEME 1902 Query: 112 AAAPSPVRAPAPSPAKEERKTE 133 S RA S + E+ + Sbjct: 1903 VLLASKARAEEESRSTSEKSKQ 1924 Score = 40.0 bits (92), Expect = 0.003 Identities = 32/99 (32%), Positives = 51/99 (51%), Gaps = 3/99 (3%) Query: 1 MEVLAAETTSQQERLQAIAEKRKRQAEIENKR-RQLEDERRQLQHLKSKALRERWLL-EG 58 MEVL A +E ++ +EK K++ E E R R+L +E +L+ L +A R+R L E Sbjct: 1901 MEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEED 1960 Query: 59 TPSSASEGDEDLRRQMQDDEQKTRL-LEDSVSRLEKEIE 96 +E + L ++ + TRL E ++ EKE E Sbjct: 1961 AARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAE 1999 Score = 37.0 bits (84), Expect = 0.026 Identities = 42/150 (28%), Positives = 67/150 (44%), Gaps = 30/150 (20%) Query: 6 AETTSQQER-----------LQAIAEKR-KRQAEIENKRRQLEDERRQLQHLKSKALRER 53 AE T+Q ER L+ AE+R ++QAE E R + E E + Q ++ALR R Sbjct: 1723 AEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLR 1782 Query: 54 WLLEGTPSSAS-----------EGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGD 102 E S E + + RR+ + +EQ R E + LEK+ ++ E Sbjct: 1783 LQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAE--- 1839 Query: 103 SAPATAKENAAAPSP-VRAPAPSPAKEERK 131 TA++ AA +R A + E+++ Sbjct: 1840 ---GTAQQRLAAEQELIRLRAETEQGEQQR 1866 Score = 37.0 bits (84), Expect = 0.026 Identities = 25/95 (26%), Positives = 50/95 (52%), Gaps = 5/95 (5%) Query: 5 AAETTSQQERLQAIAEKRKRQAEIENKRRQLEDER--RQLQHLKSKALRERWLLEGTPSS 62 A E + + QA AEK +++AE E RR ++ RQ Q ++ + + E T Sbjct: 2258 AEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQ 2317 Query: 63 ASEGDED---LRRQMQDDEQKTRLLEDSVSRLEKE 94 ++ +++ LR Q+++ + + LL++ + RL+ E Sbjct: 2318 KAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAE 2352 Score = 36.6 bits (83), Expect = 0.034 Identities = 30/112 (26%), Positives = 56/112 (50%), Gaps = 9/112 (8%) Query: 5 AAETTSQQERLQAIAEKRKRQAEIENKR-RQLEDERRQLQHLKSKALRERWLLEGTPSSA 63 A E +Q+ + Q AE+ +RQ + E++R RQ E E +++A RE+ A Sbjct: 1619 AEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREK-------QRA 1671 Query: 64 SEGDEDLRRQMQDDEQKTRLLE-DSVSRLEKEIEVLERGDSAPATAKENAAA 114 + E+LR Q ++ E++ R E + +++ +E +R A +K + A Sbjct: 1672 LQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFA 1723 Score = 35.4 bits (80), Expect = 0.075 Identities = 23/97 (23%), Positives = 47/97 (48%), Gaps = 3/97 (3%) Query: 18 IAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSASEGDEDLRRQMQDD 77 +A+ ++ + E + +++Q+E ER++L +A R + E E+L++ Q Sbjct: 2661 VAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAE---EGVRRKQEELQQLEQQR 2717 Query: 78 EQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAA 114 Q+ LL + RL +++++LE A E A Sbjct: 2718 RQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTA 2754 Score = 33.9 bits (76), Expect = 0.22 Identities = 73/355 (20%), Positives = 137/355 (38%), Gaps = 40/355 (11%) Query: 2 EVLAAETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPS 61 E LAA + + + +A ++++AE E RR EDE Q + L+ +A + + +E + Sbjct: 1974 EKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLA 2033 Query: 62 SASE-GDEDLRRQ---MQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAAPSP 117 + D +L RQ ++D ++ R +E+ + L+ E A A E Sbjct: 2034 QLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFE------KAAAGKAELELELGR 2087 Query: 118 VRAPAPSPAKEERKTEVVMNSQQTPVGTPKDKRVSNTPLRTVDGSPMMKAVVHAVDGTAE 177 +R+ A + + + E+ ++Q + +++R R + K++ + + Sbjct: 2088 IRSNAEDTLRSKEQAELEA-ARQRQLAAEEERRRREAEER------VQKSLAAEEEAARQ 2140 Query: 178 NGIHPLSSSEVDELIHKADEV-TLSEAGSTAGAAETRGAVEGAARTTPSRREITGVQAQP 236 + EV+ L K +E L E A + + A E A + + + Q Sbjct: 2141 ---RKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQ 2197 Query: 237 GEATSGPPGIQPGQEPPVTMIFMG----YQNVEDEAETKKVLGLQDTITAELVVIEDAAE 292 E +Q QE V G + +EAE +V ++ + V E+A Sbjct: 2198 KEQEL-QQTLQ--QEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQV-EEAER 2253 Query: 293 PKEPAPPNGSAAEPPTEAASREENQAGPEAT-----------TSDPQDLDMKKHR 336 K+ A A AA + +A EA D +M+KH+ Sbjct: 2254 LKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHK 2308 Score = 31.2 bits (69), Expect = 1.4 Identities = 25/98 (25%), Positives = 47/98 (47%), Gaps = 5/98 (5%) Query: 2 EVLAAETTS-QQERLQAIAEKRKRQAEIENKRRQLE----DERRQLQHLKSKALRERWLL 56 E L ET + QQ L +R+ IE ++ +LE DE + Q L+ + R++ + Sbjct: 2619 EQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQM 2678 Query: 57 EGTPSSASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKE 94 E E+ RR+ + E+ R ++ + +LE++ Sbjct: 2679 EQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQ 2716 >gi|41322908 plectin 1 isoform 3 [Homo sapiens] Length = 4525 Score = 53.5 bits (127), Expect = 3e-07 Identities = 42/142 (29%), Positives = 72/142 (50%), Gaps = 12/142 (8%) Query: 4 LAAETTSQQERL-QAIAEKRKRQAEIENKRRQLEDER--RQLQHLKSKALRERWLLEGTP 60 L AE +QQ+ L QA AEK+K +AE E +RR +E+ RQ + + + ++R L EGT Sbjct: 1624 LQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTA 1683 Query: 61 SSASEGDED---LRRQMQDDEQKTRLLEDSVSRLEKEIEVLER------GDSAPATAKEN 111 +++ LR + + EQ+ +LLE+ ++RL++E + + A A+ Sbjct: 1684 QQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEME 1743 Query: 112 AAAPSPVRAPAPSPAKEERKTE 133 S RA S + E+ + Sbjct: 1744 VLLASKARAEEESRSTSEKSKQ 1765 Score = 40.0 bits (92), Expect = 0.003 Identities = 32/99 (32%), Positives = 51/99 (51%), Gaps = 3/99 (3%) Query: 1 MEVLAAETTSQQERLQAIAEKRKRQAEIENKR-RQLEDERRQLQHLKSKALRERWLL-EG 58 MEVL A +E ++ +EK K++ E E R R+L +E +L+ L +A R+R L E Sbjct: 1742 MEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEED 1801 Query: 59 TPSSASEGDEDLRRQMQDDEQKTRL-LEDSVSRLEKEIE 96 +E + L ++ + TRL E ++ EKE E Sbjct: 1802 AARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAE 1840 Score = 37.0 bits (84), Expect = 0.026 Identities = 42/150 (28%), Positives = 67/150 (44%), Gaps = 30/150 (20%) Query: 6 AETTSQQER-----------LQAIAEKR-KRQAEIENKRRQLEDERRQLQHLKSKALRER 53 AE T+Q ER L+ AE+R ++QAE E R + E E + Q ++ALR R Sbjct: 1564 AEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLR 1623 Query: 54 WLLEGTPSSAS-----------EGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGD 102 E S E + + RR+ + +EQ R E + LEK+ ++ E Sbjct: 1624 LQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAE--- 1680 Query: 103 SAPATAKENAAAPSP-VRAPAPSPAKEERK 131 TA++ AA +R A + E+++ Sbjct: 1681 ---GTAQQRLAAEQELIRLRAETEQGEQQR 1707 Score = 37.0 bits (84), Expect = 0.026 Identities = 25/95 (26%), Positives = 50/95 (52%), Gaps = 5/95 (5%) Query: 5 AAETTSQQERLQAIAEKRKRQAEIENKRRQLEDER--RQLQHLKSKALRERWLLEGTPSS 62 A E + + QA AEK +++AE E RR ++ RQ Q ++ + + E T Sbjct: 2099 AEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQ 2158 Query: 63 ASEGDED---LRRQMQDDEQKTRLLEDSVSRLEKE 94 ++ +++ LR Q+++ + + LL++ + RL+ E Sbjct: 2159 KAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAE 2193 Score = 36.6 bits (83), Expect = 0.034 Identities = 30/112 (26%), Positives = 56/112 (50%), Gaps = 9/112 (8%) Query: 5 AAETTSQQERLQAIAEKRKRQAEIENKR-RQLEDERRQLQHLKSKALRERWLLEGTPSSA 63 A E +Q+ + Q AE+ +RQ + E++R RQ E E +++A RE+ A Sbjct: 1460 AEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREK-------QRA 1512 Query: 64 SEGDEDLRRQMQDDEQKTRLLE-DSVSRLEKEIEVLERGDSAPATAKENAAA 114 + E+LR Q ++ E++ R E + +++ +E +R A +K + A Sbjct: 1513 LQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFA 1564 Score = 35.4 bits (80), Expect = 0.075 Identities = 23/97 (23%), Positives = 47/97 (48%), Gaps = 3/97 (3%) Query: 18 IAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSASEGDEDLRRQMQDD 77 +A+ ++ + E + +++Q+E ER++L +A R + E E+L++ Q Sbjct: 2502 VAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAE---EGVRRKQEELQQLEQQR 2558 Query: 78 EQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAA 114 Q+ LL + RL +++++LE A E A Sbjct: 2559 RQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTA 2595 Score = 33.9 bits (76), Expect = 0.22 Identities = 73/355 (20%), Positives = 137/355 (38%), Gaps = 40/355 (11%) Query: 2 EVLAAETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPS 61 E LAA + + + +A ++++AE E RR EDE Q + L+ +A + + +E + Sbjct: 1815 EKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLA 1874 Query: 62 SASE-GDEDLRRQ---MQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAAPSP 117 + D +L RQ ++D ++ R +E+ + L+ E A A E Sbjct: 1875 QLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFE------KAAAGKAELELELGR 1928 Query: 118 VRAPAPSPAKEERKTEVVMNSQQTPVGTPKDKRVSNTPLRTVDGSPMMKAVVHAVDGTAE 177 +R+ A + + + E+ ++Q + +++R R + K++ + + Sbjct: 1929 IRSNAEDTLRSKEQAELEA-ARQRQLAAEEERRRREAEER------VQKSLAAEEEAARQ 1981 Query: 178 NGIHPLSSSEVDELIHKADEV-TLSEAGSTAGAAETRGAVEGAARTTPSRREITGVQAQP 236 + EV+ L K +E L E A + + A E A + + + Q Sbjct: 1982 ---RKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQ 2038 Query: 237 GEATSGPPGIQPGQEPPVTMIFMG----YQNVEDEAETKKVLGLQDTITAELVVIEDAAE 292 E +Q QE V G + +EAE +V ++ + V E+A Sbjct: 2039 KEQEL-QQTLQ--QEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQV-EEAER 2094 Query: 293 PKEPAPPNGSAAEPPTEAASREENQAGPEAT-----------TSDPQDLDMKKHR 336 K+ A A AA + +A EA D +M+KH+ Sbjct: 2095 LKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHK 2149 Score = 31.2 bits (69), Expect = 1.4 Identities = 25/98 (25%), Positives = 47/98 (47%), Gaps = 5/98 (5%) Query: 2 EVLAAETTS-QQERLQAIAEKRKRQAEIENKRRQLE----DERRQLQHLKSKALRERWLL 56 E L ET + QQ L +R+ IE ++ +LE DE + Q L+ + R++ + Sbjct: 2460 EQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQM 2519 Query: 57 EGTPSSASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKE 94 E E+ RR+ + E+ R ++ + +LE++ Sbjct: 2520 EQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQ 2557 >gi|41322912 plectin 1 isoform 2 [Homo sapiens] Length = 4533 Score = 53.5 bits (127), Expect = 3e-07 Identities = 42/142 (29%), Positives = 72/142 (50%), Gaps = 12/142 (8%) Query: 4 LAAETTSQQERL-QAIAEKRKRQAEIENKRRQLEDER--RQLQHLKSKALRERWLLEGTP 60 L AE +QQ+ L QA AEK+K +AE E +RR +E+ RQ + + + ++R L EGT Sbjct: 1632 LQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTA 1691 Query: 61 SSASEGDED---LRRQMQDDEQKTRLLEDSVSRLEKEIEVLER------GDSAPATAKEN 111 +++ LR + + EQ+ +LLE+ ++RL++E + + A A+ Sbjct: 1692 QQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEME 1751 Query: 112 AAAPSPVRAPAPSPAKEERKTE 133 S RA S + E+ + Sbjct: 1752 VLLASKARAEEESRSTSEKSKQ 1773 Score = 40.0 bits (92), Expect = 0.003 Identities = 32/99 (32%), Positives = 51/99 (51%), Gaps = 3/99 (3%) Query: 1 MEVLAAETTSQQERLQAIAEKRKRQAEIENKR-RQLEDERRQLQHLKSKALRERWLL-EG 58 MEVL A +E ++ +EK K++ E E R R+L +E +L+ L +A R+R L E Sbjct: 1750 MEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEED 1809 Query: 59 TPSSASEGDEDLRRQMQDDEQKTRL-LEDSVSRLEKEIE 96 +E + L ++ + TRL E ++ EKE E Sbjct: 1810 AARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAE 1848 Score = 37.0 bits (84), Expect = 0.026 Identities = 42/150 (28%), Positives = 67/150 (44%), Gaps = 30/150 (20%) Query: 6 AETTSQQER-----------LQAIAEKR-KRQAEIENKRRQLEDERRQLQHLKSKALRER 53 AE T+Q ER L+ AE+R ++QAE E R + E E + Q ++ALR R Sbjct: 1572 AEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLR 1631 Query: 54 WLLEGTPSSAS-----------EGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGD 102 E S E + + RR+ + +EQ R E + LEK+ ++ E Sbjct: 1632 LQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAE--- 1688 Query: 103 SAPATAKENAAAPSP-VRAPAPSPAKEERK 131 TA++ AA +R A + E+++ Sbjct: 1689 ---GTAQQRLAAEQELIRLRAETEQGEQQR 1715 Score = 37.0 bits (84), Expect = 0.026 Identities = 25/95 (26%), Positives = 50/95 (52%), Gaps = 5/95 (5%) Query: 5 AAETTSQQERLQAIAEKRKRQAEIENKRRQLEDER--RQLQHLKSKALRERWLLEGTPSS 62 A E + + QA AEK +++AE E RR ++ RQ Q ++ + + E T Sbjct: 2107 AEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQ 2166 Query: 63 ASEGDED---LRRQMQDDEQKTRLLEDSVSRLEKE 94 ++ +++ LR Q+++ + + LL++ + RL+ E Sbjct: 2167 KAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAE 2201 Score = 36.6 bits (83), Expect = 0.034 Identities = 30/112 (26%), Positives = 56/112 (50%), Gaps = 9/112 (8%) Query: 5 AAETTSQQERLQAIAEKRKRQAEIENKR-RQLEDERRQLQHLKSKALRERWLLEGTPSSA 63 A E +Q+ + Q AE+ +RQ + E++R RQ E E +++A RE+ A Sbjct: 1468 AEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREK-------QRA 1520 Query: 64 SEGDEDLRRQMQDDEQKTRLLE-DSVSRLEKEIEVLERGDSAPATAKENAAA 114 + E+LR Q ++ E++ R E + +++ +E +R A +K + A Sbjct: 1521 LQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFA 1572 Score = 35.4 bits (80), Expect = 0.075 Identities = 23/97 (23%), Positives = 47/97 (48%), Gaps = 3/97 (3%) Query: 18 IAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSASEGDEDLRRQMQDD 77 +A+ ++ + E + +++Q+E ER++L +A R + E E+L++ Q Sbjct: 2510 VAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAE---EGVRRKQEELQQLEQQR 2566 Query: 78 EQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAA 114 Q+ LL + RL +++++LE A E A Sbjct: 2567 RQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTA 2603 Score = 33.9 bits (76), Expect = 0.22 Identities = 73/355 (20%), Positives = 137/355 (38%), Gaps = 40/355 (11%) Query: 2 EVLAAETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPS 61 E LAA + + + +A ++++AE E RR EDE Q + L+ +A + + +E + Sbjct: 1823 EKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLA 1882 Query: 62 SASE-GDEDLRRQ---MQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAAPSP 117 + D +L RQ ++D ++ R +E+ + L+ E A A E Sbjct: 1883 QLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFE------KAAAGKAELELELGR 1936 Query: 118 VRAPAPSPAKEERKTEVVMNSQQTPVGTPKDKRVSNTPLRTVDGSPMMKAVVHAVDGTAE 177 +R+ A + + + E+ ++Q + +++R R + K++ + + Sbjct: 1937 IRSNAEDTLRSKEQAELEA-ARQRQLAAEEERRRREAEER------VQKSLAAEEEAARQ 1989 Query: 178 NGIHPLSSSEVDELIHKADEV-TLSEAGSTAGAAETRGAVEGAARTTPSRREITGVQAQP 236 + EV+ L K +E L E A + + A E A + + + Q Sbjct: 1990 ---RKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQ 2046 Query: 237 GEATSGPPGIQPGQEPPVTMIFMG----YQNVEDEAETKKVLGLQDTITAELVVIEDAAE 292 E +Q QE V G + +EAE +V ++ + V E+A Sbjct: 2047 KEQEL-QQTLQ--QEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQV-EEAER 2102 Query: 293 PKEPAPPNGSAAEPPTEAASREENQAGPEAT-----------TSDPQDLDMKKHR 336 K+ A A AA + +A EA D +M+KH+ Sbjct: 2103 LKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHK 2157 Score = 31.2 bits (69), Expect = 1.4 Identities = 25/98 (25%), Positives = 47/98 (47%), Gaps = 5/98 (5%) Query: 2 EVLAAETTS-QQERLQAIAEKRKRQAEIENKRRQLE----DERRQLQHLKSKALRERWLL 56 E L ET + QQ L +R+ IE ++ +LE DE + Q L+ + R++ + Sbjct: 2468 EQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQM 2527 Query: 57 EGTPSSASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKE 94 E E+ RR+ + E+ R ++ + +LE++ Sbjct: 2528 EQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQ 2565 >gi|47607492 plectin 1 isoform 1 [Homo sapiens] Length = 4574 Score = 53.5 bits (127), Expect = 3e-07 Identities = 42/142 (29%), Positives = 72/142 (50%), Gaps = 12/142 (8%) Query: 4 LAAETTSQQERL-QAIAEKRKRQAEIENKRRQLEDER--RQLQHLKSKALRERWLLEGTP 60 L AE +QQ+ L QA AEK+K +AE E +RR +E+ RQ + + + ++R L EGT Sbjct: 1673 LQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTA 1732 Query: 61 SSASEGDED---LRRQMQDDEQKTRLLEDSVSRLEKEIEVLER------GDSAPATAKEN 111 +++ LR + + EQ+ +LLE+ ++RL++E + + A A+ Sbjct: 1733 QQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEME 1792 Query: 112 AAAPSPVRAPAPSPAKEERKTE 133 S RA S + E+ + Sbjct: 1793 VLLASKARAEEESRSTSEKSKQ 1814 Score = 40.0 bits (92), Expect = 0.003 Identities = 32/99 (32%), Positives = 51/99 (51%), Gaps = 3/99 (3%) Query: 1 MEVLAAETTSQQERLQAIAEKRKRQAEIENKR-RQLEDERRQLQHLKSKALRERWLL-EG 58 MEVL A +E ++ +EK K++ E E R R+L +E +L+ L +A R+R L E Sbjct: 1791 MEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEED 1850 Query: 59 TPSSASEGDEDLRRQMQDDEQKTRL-LEDSVSRLEKEIE 96 +E + L ++ + TRL E ++ EKE E Sbjct: 1851 AARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAE 1889 Score = 37.0 bits (84), Expect = 0.026 Identities = 42/150 (28%), Positives = 67/150 (44%), Gaps = 30/150 (20%) Query: 6 AETTSQQER-----------LQAIAEKR-KRQAEIENKRRQLEDERRQLQHLKSKALRER 53 AE T+Q ER L+ AE+R ++QAE E R + E E + Q ++ALR R Sbjct: 1613 AEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLR 1672 Query: 54 WLLEGTPSSAS-----------EGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGD 102 E S E + + RR+ + +EQ R E + LEK+ ++ E Sbjct: 1673 LQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAE--- 1729 Query: 103 SAPATAKENAAAPSP-VRAPAPSPAKEERK 131 TA++ AA +R A + E+++ Sbjct: 1730 ---GTAQQRLAAEQELIRLRAETEQGEQQR 1756 Score = 37.0 bits (84), Expect = 0.026 Identities = 25/95 (26%), Positives = 50/95 (52%), Gaps = 5/95 (5%) Query: 5 AAETTSQQERLQAIAEKRKRQAEIENKRRQLEDER--RQLQHLKSKALRERWLLEGTPSS 62 A E + + QA AEK +++AE E RR ++ RQ Q ++ + + E T Sbjct: 2148 AEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQ 2207 Query: 63 ASEGDED---LRRQMQDDEQKTRLLEDSVSRLEKE 94 ++ +++ LR Q+++ + + LL++ + RL+ E Sbjct: 2208 KAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAE 2242 Score = 36.6 bits (83), Expect = 0.034 Identities = 30/112 (26%), Positives = 56/112 (50%), Gaps = 9/112 (8%) Query: 5 AAETTSQQERLQAIAEKRKRQAEIENKR-RQLEDERRQLQHLKSKALRERWLLEGTPSSA 63 A E +Q+ + Q AE+ +RQ + E++R RQ E E +++A RE+ A Sbjct: 1509 AEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREK-------QRA 1561 Query: 64 SEGDEDLRRQMQDDEQKTRLLE-DSVSRLEKEIEVLERGDSAPATAKENAAA 114 + E+LR Q ++ E++ R E + +++ +E +R A +K + A Sbjct: 1562 LQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFA 1613 Score = 35.4 bits (80), Expect = 0.075 Identities = 23/97 (23%), Positives = 47/97 (48%), Gaps = 3/97 (3%) Query: 18 IAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSASEGDEDLRRQMQDD 77 +A+ ++ + E + +++Q+E ER++L +A R + E E+L++ Q Sbjct: 2551 VAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAE---EGVRRKQEELQQLEQQR 2607 Query: 78 EQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAA 114 Q+ LL + RL +++++LE A E A Sbjct: 2608 RQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTA 2644 Score = 33.9 bits (76), Expect = 0.22 Identities = 73/355 (20%), Positives = 137/355 (38%), Gaps = 40/355 (11%) Query: 2 EVLAAETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPS 61 E LAA + + + +A ++++AE E RR EDE Q + L+ +A + + +E + Sbjct: 1864 EKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLA 1923 Query: 62 SASE-GDEDLRRQ---MQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAAPSP 117 + D +L RQ ++D ++ R +E+ + L+ E A A E Sbjct: 1924 QLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFE------KAAAGKAELELELGR 1977 Query: 118 VRAPAPSPAKEERKTEVVMNSQQTPVGTPKDKRVSNTPLRTVDGSPMMKAVVHAVDGTAE 177 +R+ A + + + E+ ++Q + +++R R + K++ + + Sbjct: 1978 IRSNAEDTLRSKEQAELEA-ARQRQLAAEEERRRREAEER------VQKSLAAEEEAARQ 2030 Query: 178 NGIHPLSSSEVDELIHKADEV-TLSEAGSTAGAAETRGAVEGAARTTPSRREITGVQAQP 236 + EV+ L K +E L E A + + A E A + + + Q Sbjct: 2031 ---RKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQ 2087 Query: 237 GEATSGPPGIQPGQEPPVTMIFMG----YQNVEDEAETKKVLGLQDTITAELVVIEDAAE 292 E +Q QE V G + +EAE +V ++ + V E+A Sbjct: 2088 KEQEL-QQTLQ--QEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQV-EEAER 2143 Query: 293 PKEPAPPNGSAAEPPTEAASREENQAGPEAT-----------TSDPQDLDMKKHR 336 K+ A A AA + +A EA D +M+KH+ Sbjct: 2144 LKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHK 2198 Score = 31.2 bits (69), Expect = 1.4 Identities = 25/98 (25%), Positives = 47/98 (47%), Gaps = 5/98 (5%) Query: 2 EVLAAETTS-QQERLQAIAEKRKRQAEIENKRRQLE----DERRQLQHLKSKALRERWLL 56 E L ET + QQ L +R+ IE ++ +LE DE + Q L+ + R++ + Sbjct: 2509 EQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQM 2568 Query: 57 EGTPSSASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKE 94 E E+ RR+ + E+ R ++ + +LE++ Sbjct: 2569 EQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQ 2606 >gi|78042577 MAP7 domain containing 1 [Homo sapiens] Length = 841 Score = 53.5 bits (127), Expect = 3e-07 Identities = 59/279 (21%), Positives = 111/279 (39%), Gaps = 28/279 (10%) Query: 6 AETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSASE 65 A TT ++E + +AEKR++ E +R+ E++ R+LQ + K +RE L + A Sbjct: 591 AGTTDREEATRLLAEKRRQARE----QREREEQERRLQAERDKRMREEQLAREAEARAER 646 Query: 66 GDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAAPSPVRAPAPSP 125 E RR+ Q+ +K + ++ RL+K+ E E A + + Sbjct: 647 EAEARRREEQEAREKAQAEQEEQERLQKQKEEAEARSREEAERQRLEREKHFQQQEQERQ 706 Query: 126 AKEERKTEVVMNSQQTPVGTPKDKRVSNTPLRTVDGSPMMKAVVHAVDGTAENGIHPLSS 185 + +R E++ ++++ V K K+ S +KAV G + + Sbjct: 707 ERRKRLEEIMKRTRKSEVSETKQKQDSKEANANGSSPEPVKAVEARSPGLQKEAV----- 761 Query: 186 SEVDELIHKADEVTLSEAGSTAGAAETRGAVEGAARTTPSRREITGVQAQPGEATSGPPG 245 + +E E + + E ++ + P+ +E G +T+GP G Sbjct: 762 --------QKEEPIPQEPQWSLPSKELPASLVNGLQPLPAHQE-------NGFSTNGPSG 806 Query: 246 IQPGQEPPVTMIFMGYQNVEDEAETKKVLGLQDTITAEL 284 + P T++ E EA KK + +T L Sbjct: 807 DKSLSRTPETLL----PFAEAEAFLKKAVVQSPQVTEVL 841 Score = 33.5 bits (75), Expect = 0.28 Identities = 19/47 (40%), Positives = 23/47 (48%), Gaps = 6/47 (12%) Query: 109 KENAAAPSPVRAPAPSPAKEERKTEVVMNSQQTPVGTPKDKRVSNTP 155 KE+AA SP +PAPSP T +Q P TP D V +P Sbjct: 537 KESAAPASPAPSPAPSP------TPAPPQKEQPPAETPTDAAVLTSP 577 Score = 28.9 bits (63), Expect = 7.0 Identities = 14/44 (31%), Positives = 20/44 (45%), Gaps = 2/44 (4%) Query: 293 PKEPAPPNGSAAEPPTEAASREENQAGPEATTSDPQDLDMKKHR 336 P +P P G+ A P +EE + P A + P+D K R Sbjct: 491 PPKPPSPRGTTASPKGRVRRKEEAKESPSA--AGPEDKSQSKRR 532 >gi|22035606 mitogen-activated protein kinase kinase kinase kinase 4 isoform 3 [Homo sapiens] Length = 1212 Score = 51.2 bits (121), Expect = 1e-06 Identities = 79/349 (22%), Positives = 137/349 (39%), Gaps = 38/349 (10%) Query: 1 MEVLAAETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLL---- 56 +E L ++ER +A EKR+ + E E RRQLE+E+R L+ L+ + L+E+ +L Sbjct: 438 LEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLLQEQAMLLHDH 497 Query: 57 -----EGTPSSASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAP-ATAKE 110 + + E + E K E + E E + S+P A +K+ Sbjct: 498 RRPHPQHSQQPPPPQQERSKPSFHAPEPKAH-YEPADRAREVEDRFRKTNHSSPEAQSKQ 556 Query: 111 NAAAPSPVRAPAPSPAKEERKTEVVMNSQQTPVGTPKDKRVSNTPLRTVDGSPMMKAVVH 170 P P P++ E + S + P + +V P+RT SP++ Sbjct: 557 TGRVLEP-----PVPSRSESFSNGNSESVHPALQRPAEPQV---PVRTTSRSPVLSRRDS 608 Query: 171 AVDGTAEN----GIHPLSSSEVDELIHKADEVTLSEAGSTAGAAETRGAVEGAARTTPSR 226 + G+ + G +SS L+ + E + GS G+ G++ + Sbjct: 609 PLQGSGQQNSQAGQRNSTSSIEPRLLWERVEKLVPRPGS--------GSSSGSSNSGSQP 660 Query: 227 REITGVQAQPGEATSGPPGIQPGQEPPVTMIFMGYQNVEDEAETKKVL---GLQD--TIT 281 G Q+ GE + P + + ED+ E + L G D + Sbjct: 661 GSHPGSQSGSGERFR-VRSSSKSEGSPSQRLENAVKKPEDKKEVFRPLKPAGEVDLTALA 719 Query: 282 AELVVIEDAAEPKEPAPPNGSAAEP-PTEAASREENQAGPEATTSDPQD 329 EL +ED P + + S+ E T+ + Q G + +TS P+D Sbjct: 720 KELRAVEDVRPPHKVTDYSSSSEESGTTDEEDDDVEQEGADESTSGPED 768 >gi|50511340 shootin1 isoform b [Homo sapiens] Length = 456 Score = 49.3 bits (116), Expect = 5e-06 Identities = 41/181 (22%), Positives = 81/181 (44%), Gaps = 11/181 (6%) Query: 3 VLAAETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQH-LKSKAL-RERWLLEGTP 60 +L + Q+ L+A+ E K ++E +R Q + + ++L+ L+++ L +E L+ Sbjct: 251 LLLQSSIPDQQLLKALDENAKLTQQLEEERIQHQQKVKELEEQLENETLHKEIHNLKQQL 310 Query: 61 SSASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAAPSPVRA 120 E ++L + Q+ E+K R L+ SV L+K + E P P P+ Sbjct: 311 ELLEEDKKELELKYQNSEEKARNLKHSVDELQKRVNQSENSVPPP------PPPPPPLPP 364 Query: 121 PAPSPAKEERKTEVVMNSQQTPVGTPKDKRVSNTPLRTVDGSPMMKAVVHAVDGTAENGI 180 P P+P R ++ + P G+ K + P T + + + + V + + G+ Sbjct: 365 PPPNPI---RSLMSMIRKRSHPSGSGAKKEKATQPETTEEVTDLKRQAVEEMMDRIKKGV 421 Query: 181 H 181 H Sbjct: 422 H 422 >gi|15826852 acyl-Coenzyme A binding domain containing 3 [Homo sapiens] Length = 528 Score = 47.0 bits (110), Expect = 2e-05 Identities = 38/127 (29%), Positives = 64/127 (50%), Gaps = 21/127 (16%) Query: 11 QQERLQAIAEKRKRQAE-----IENKRRQLEDERRQLQHLKSK---ALRERWLLEGTPSS 62 ++ERLQ EKR+R+ E E +RR++E+ER +L+ K + AL + ++ + Sbjct: 203 ERERLQKEEEKRRREEEERLRREEEERRRIEEERLRLEQQKQQIMAALNSQTAVQFQQYA 262 Query: 63 AS------EGDEDLRRQMQDDEQKTRL-------LEDSVSRLEKEIEVLERGDSAPATAK 109 A E + L RQ+Q+ + + L + L+K+ EV+ G S P ++K Sbjct: 263 AQQYPGNYEQQQILIRQLQEQHYQQYMQQLYQVQLAQQQAALQKQQEVVVAGSSLPTSSK 322 Query: 110 ENAAAPS 116 NA PS Sbjct: 323 VNATVPS 329 Score = 35.0 bits (79), Expect = 0.098 Identities = 24/75 (32%), Positives = 40/75 (53%), Gaps = 17/75 (22%) Query: 20 EKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSASEGDEDLRRQMQDDEQ 79 E+ K++ E E +RR+ E+ER +LQ + K RE +E LRR +E+ Sbjct: 185 EQEKKRKEEEERRRREEEERERLQKEEEKRRREE-------------EERLRR----EEE 227 Query: 80 KTRLLEDSVSRLEKE 94 + R +E+ RLE++ Sbjct: 228 ERRRIEEERLRLEQQ 242 >gi|189181724 proteoglycan 4 isoform D [Homo sapiens] Length = 1270 Score = 46.6 bits (109), Expect = 3e-05 Identities = 58/245 (23%), Positives = 87/245 (35%), Gaps = 21/245 (8%) Query: 102 DSAPATAKENA------AAPSPVRAPAPSPAKEERKTEVVMNSQQTPVGTPKDKRVSNTP 155 + AP T KE A AP+ ++ PAP+ K+ E+ + + P T DK TP Sbjct: 561 EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTP 620 Query: 156 LRTVDGSPMMKAVVHAVD--GTAENGIHPLSSSEVDELIHKADEVTLSEAGSTAGAAETR 213 T +P A + T G P + E K + E T T Sbjct: 621 KGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPK--KPAPKELAPTTTKGPTS 678 Query: 214 GAVEGAARTTPSRREITGVQAQPGEATSGPPGIQPGQEPPVTMIFMGYQNVEDEAETKKV 273 + A TTP T +P T P + PP T + E T Sbjct: 679 TTSDKPAPTTPKETAPT-TPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHK 737 Query: 274 LGLQDT--ITAELVVIEDAAEPKEPAPP---NGSAAEPPTEAASREEN-----QAGPEAT 323 + T ++AE PKEP P +A +P ++++ + PE T Sbjct: 738 SPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETT 797 Query: 324 TSDPQ 328 T+ P+ Sbjct: 798 TAAPK 802 Score = 41.6 bits (96), Expect = 0.001 Identities = 57/227 (25%), Positives = 72/227 (31%), Gaps = 23/227 (10%) Query: 103 SAPATAKENAAAPSPVRAPAPSPAKEERKT---EVVMNSQQTPVGTPKDKRVSNTPLRTV 159 SAP T KE AP+ + PAP+ KE T E + ++ TPK+ TP + Sbjct: 254 SAPTTPKE--PAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEP-APTTPKKPA 310 Query: 160 DGSPMMKAVVHAVDGTAENGIHPLSSSEVDELIHKADEVTLSEAGSTAGAAETRGAVEGA 219 +P A P + E K T E T A + Sbjct: 311 PTTPKEPA--------------PTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKP 356 Query: 220 ARTTPSRREITGVQAQPGEATSGPPGIQPGQEPPVTMIFMGYQNVEDEAETKKVLGLQDT 279 A TTP T + T P P + P T E T K Sbjct: 357 APTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPK 416 Query: 280 ITAELVVIEDA-AEPKEPAP--PNGSAAEPPTEAASREENQAGPEAT 323 + E A PKEPAP P A P E A + P T Sbjct: 417 EPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT 463 Score = 35.0 bits (79), Expect = 0.098 Identities = 63/244 (25%), Positives = 85/244 (34%), Gaps = 29/244 (11%) Query: 102 DSAPATAKENAAAPSPVRAPAPSPAKEERKTEVVMNSQQTP---VGTPKDKRVSNTPLRT 158 + AP T KE AP+ + PAP+ KE T + TP T +K TP + Sbjct: 449 EPAPTTPKE--PAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKP 506 Query: 159 VDGSPMMKAVVHAVDGTAENGIHPLSSSEVDELIHKADE---VTLSEAGSTAGAAETRGA 215 +P A + T P ++ + E T E T Sbjct: 507 APTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT 566 Query: 216 VEGAARTTPSRREITGVQAQPGEATSGPPGIQPGQEPPVTMIFMGYQNVEDEAETKKVLG 275 + A TTP T ++ +P T P P + P T + A T G Sbjct: 567 PKETAPTTPKGTAPTTLK-EPAPTTPKKPA--PKELAPTTTKEPTSTTCDKPAPTTP-KG 622 Query: 276 LQDTITAELVVIEDAAEPKEPAP--PNGSA----AEP----PTEAASRE---ENQAGPEA 322 T E PKEPAP P G+A EP P + A +E GP + Sbjct: 623 TAPTTPKE----PAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTS 678 Query: 323 TTSD 326 TTSD Sbjct: 679 TTSD 682 Score = 34.3 bits (77), Expect = 0.17 Identities = 58/228 (25%), Positives = 73/228 (32%), Gaps = 30/228 (13%) Query: 105 PATAKENAAAPSPVRAPAPSPAKEERKTEVVMNSQQTPVGTPKDKRVSNTPLRTVDGSPM 164 PA AAAP+ + PAP+ KE T TPK+ TP T +P Sbjct: 530 PAPTTPKAAAPNTPKEPAPTTPKEPAPT------------TPKEP-APTTPKETAPTTP- 575 Query: 165 MKAVVHAVDGTAENGI-HPLSSSEVDELIHKADEVTLSEAGSTAGAAETRGAVEGAARTT 223 GTA + P ++ + T E ST +G A TT Sbjct: 576 --------KGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTT 627 Query: 224 PSRREITGVQAQPGEATSGPPGIQPG--QEPPVTMIFMGYQNVEDEAETKKVLGLQDTIT 281 P T +P T P G P +EP T TK Sbjct: 628 PKEPAPT-TPKEPAPTT--PKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKP 684 Query: 282 AELVVIEDA-AEPKEPAPPNGSAAEPPT-EAASREENQAGPEATTSDP 327 A E A PKEPAP P T E ++ TT +P Sbjct: 685 APTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEP 732 Score = 31.2 bits (69), Expect = 1.4 Identities = 52/232 (22%), Positives = 74/232 (31%), Gaps = 28/232 (12%) Query: 102 DSAPATAKENAA------APSPVRAPAPSPAKEERKTEVVMNSQQTPVGTPKDKRVSNTP 155 + AP T KE A AP+ + PAP+ KE T + + P T + TP Sbjct: 425 EPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPT-----TTKKPAPTTPKEPAPTTP 479 Query: 156 LRTVDGSPMMKAVVHAVDGTAENGIHPLSSSEVDELIHKADE----VTLSEAGSTAGAAE 211 T +P K + A + + +EL E T E T A Sbjct: 480 KETAPTTP-KKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAA 538 Query: 212 TRGAVEGAARTTPSRREITGVQAQPGEATSGPPG-IQPGQEPPVTMIFMGYQNVEDEAET 270 + A TTP +P T P P + P T +++ A T Sbjct: 539 APNTPKEPAPTTPK---------EPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPT 589 Query: 271 --KKVLGLQDTITAELVVIEDAAEPKEPAPPNGSAAEPPTEAASREENQAGP 320 KK + T + P P G+A P E A + P Sbjct: 590 TPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAP 641 Score = 28.5 bits (62), Expect = 9.1 Identities = 49/229 (21%), Positives = 83/229 (36%), Gaps = 15/229 (6%) Query: 109 KENAAAPSPVRAPAPSPAKEERKTEVVMNSQQTPVGTPKDKRVSNTPLRTVDGSPMMKAV 168 K A P R P + ++T + +N ++T V T K+ +N T DG + Sbjct: 117 KITTAKPINPRPSLPPNSDTSKETSLTVN-KETTVET-KETTTTNKQTST-DGKEKTTSA 173 Query: 169 --VHAVDGTAENGIHPLSSSEVDELIHKADEVTLSEAGSTAGAAETRGAVEGAARTTPSR 226 +++ T+ + P +S + + KA+ T A +T T + A TTP Sbjct: 174 KETQSIEKTSAKDLAP-TSKVLAKPTPKAETTTKGPALTTP-KEPTPTTPKEPASTTPKE 231 Query: 227 REITGVQA------QPGEATSGPPGIQPGQEPPVTMIFMGYQNVEDEAETKKVLGLQDTI 280 T +++ +P T+ P + P T ++ A T T Sbjct: 232 PTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTT 291 Query: 281 TAELVVIEDAAE--PKEPAPPNGSAAEPPTEAASREENQAGPEATTSDP 327 + ++ A PK+PAP P T P TT +P Sbjct: 292 KSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEP 340 >gi|189181722 proteoglycan 4 isoform C [Homo sapiens] Length = 1311 Score = 46.6 bits (109), Expect = 3e-05 Identities = 58/245 (23%), Positives = 87/245 (35%), Gaps = 21/245 (8%) Query: 102 DSAPATAKENA------AAPSPVRAPAPSPAKEERKTEVVMNSQQTPVGTPKDKRVSNTP 155 + AP T KE A AP+ ++ PAP+ K+ E+ + + P T DK TP Sbjct: 602 EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTP 661 Query: 156 LRTVDGSPMMKAVVHAVD--GTAENGIHPLSSSEVDELIHKADEVTLSEAGSTAGAAETR 213 T +P A + T G P + E K + E T T Sbjct: 662 KGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPK--KPAPKELAPTTTKGPTS 719 Query: 214 GAVEGAARTTPSRREITGVQAQPGEATSGPPGIQPGQEPPVTMIFMGYQNVEDEAETKKV 273 + A TTP T +P T P + PP T + E T Sbjct: 720 TTSDKPAPTTPKETAPT-TPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHK 778 Query: 274 LGLQDT--ITAELVVIEDAAEPKEPAPP---NGSAAEPPTEAASREEN-----QAGPEAT 323 + T ++AE PKEP P +A +P ++++ + PE T Sbjct: 779 SPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETT 838 Query: 324 TSDPQ 328 T+ P+ Sbjct: 839 TAAPK 843 Score = 41.6 bits (96), Expect = 0.001 Identities = 57/227 (25%), Positives = 72/227 (31%), Gaps = 23/227 (10%) Query: 103 SAPATAKENAAAPSPVRAPAPSPAKEERKT---EVVMNSQQTPVGTPKDKRVSNTPLRTV 159 SAP T KE AP+ + PAP+ KE T E + ++ TPK+ TP + Sbjct: 295 SAPTTPKE--PAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEP-APTTPKKPA 351 Query: 160 DGSPMMKAVVHAVDGTAENGIHPLSSSEVDELIHKADEVTLSEAGSTAGAAETRGAVEGA 219 +P A P + E K T E T A + Sbjct: 352 PTTPKEPA--------------PTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKP 397 Query: 220 ARTTPSRREITGVQAQPGEATSGPPGIQPGQEPPVTMIFMGYQNVEDEAETKKVLGLQDT 279 A TTP T + T P P + P T E T K Sbjct: 398 APTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPK 457 Query: 280 ITAELVVIEDA-AEPKEPAP--PNGSAAEPPTEAASREENQAGPEAT 323 + E A PKEPAP P A P E A + P T Sbjct: 458 EPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT 504 Score = 35.0 bits (79), Expect = 0.098 Identities = 63/244 (25%), Positives = 85/244 (34%), Gaps = 29/244 (11%) Query: 102 DSAPATAKENAAAPSPVRAPAPSPAKEERKTEVVMNSQQTP---VGTPKDKRVSNTPLRT 158 + AP T KE AP+ + PAP+ KE T + TP T +K TP + Sbjct: 490 EPAPTTPKE--PAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKP 547 Query: 159 VDGSPMMKAVVHAVDGTAENGIHPLSSSEVDELIHKADE---VTLSEAGSTAGAAETRGA 215 +P A + T P ++ + E T E T Sbjct: 548 APTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT 607 Query: 216 VEGAARTTPSRREITGVQAQPGEATSGPPGIQPGQEPPVTMIFMGYQNVEDEAETKKVLG 275 + A TTP T ++ +P T P P + P T + A T G Sbjct: 608 PKETAPTTPKGTAPTTLK-EPAPTTPKKPA--PKELAPTTTKEPTSTTCDKPAPTTP-KG 663 Query: 276 LQDTITAELVVIEDAAEPKEPAP--PNGSA----AEP----PTEAASRE---ENQAGPEA 322 T E PKEPAP P G+A EP P + A +E GP + Sbjct: 664 TAPTTPKE----PAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTS 719 Query: 323 TTSD 326 TTSD Sbjct: 720 TTSD 723 Score = 34.3 bits (77), Expect = 0.17 Identities = 58/228 (25%), Positives = 73/228 (32%), Gaps = 30/228 (13%) Query: 105 PATAKENAAAPSPVRAPAPSPAKEERKTEVVMNSQQTPVGTPKDKRVSNTPLRTVDGSPM 164 PA AAAP+ + PAP+ KE T TPK+ TP T +P Sbjct: 571 PAPTTPKAAAPNTPKEPAPTTPKEPAPT------------TPKEP-APTTPKETAPTTP- 616 Query: 165 MKAVVHAVDGTAENGI-HPLSSSEVDELIHKADEVTLSEAGSTAGAAETRGAVEGAARTT 223 GTA + P ++ + T E ST +G A TT Sbjct: 617 --------KGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTT 668 Query: 224 PSRREITGVQAQPGEATSGPPGIQPG--QEPPVTMIFMGYQNVEDEAETKKVLGLQDTIT 281 P T +P T P G P +EP T TK Sbjct: 669 PKEPAPT-TPKEPAPTT--PKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKP 725 Query: 282 AELVVIEDA-AEPKEPAPPNGSAAEPPT-EAASREENQAGPEATTSDP 327 A E A PKEPAP P T E ++ TT +P Sbjct: 726 APTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEP 773 Score = 31.2 bits (69), Expect = 1.4 Identities = 52/232 (22%), Positives = 74/232 (31%), Gaps = 28/232 (12%) Query: 102 DSAPATAKENAA------APSPVRAPAPSPAKEERKTEVVMNSQQTPVGTPKDKRVSNTP 155 + AP T KE A AP+ + PAP+ KE T + + P T + TP Sbjct: 466 EPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPT-----TTKKPAPTTPKEPAPTTP 520 Query: 156 LRTVDGSPMMKAVVHAVDGTAENGIHPLSSSEVDELIHKADE----VTLSEAGSTAGAAE 211 T +P K + A + + +EL E T E T A Sbjct: 521 KETAPTTP-KKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAA 579 Query: 212 TRGAVEGAARTTPSRREITGVQAQPGEATSGPPG-IQPGQEPPVTMIFMGYQNVEDEAET 270 + A TTP +P T P P + P T +++ A T Sbjct: 580 APNTPKEPAPTTPK---------EPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPT 630 Query: 271 --KKVLGLQDTITAELVVIEDAAEPKEPAPPNGSAAEPPTEAASREENQAGP 320 KK + T + P P G+A P E A + P Sbjct: 631 TPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAP 682 Score = 28.5 bits (62), Expect = 9.1 Identities = 49/229 (21%), Positives = 83/229 (36%), Gaps = 15/229 (6%) Query: 109 KENAAAPSPVRAPAPSPAKEERKTEVVMNSQQTPVGTPKDKRVSNTPLRTVDGSPMMKAV 168 K A P R P + ++T + +N ++T V T K+ +N T DG + Sbjct: 158 KITTAKPINPRPSLPPNSDTSKETSLTVN-KETTVET-KETTTTNKQTST-DGKEKTTSA 214 Query: 169 --VHAVDGTAENGIHPLSSSEVDELIHKADEVTLSEAGSTAGAAETRGAVEGAARTTPSR 226 +++ T+ + P +S + + KA+ T A +T T + A TTP Sbjct: 215 KETQSIEKTSAKDLAP-TSKVLAKPTPKAETTTKGPALTTP-KEPTPTTPKEPASTTPKE 272 Query: 227 REITGVQA------QPGEATSGPPGIQPGQEPPVTMIFMGYQNVEDEAETKKVLGLQDTI 280 T +++ +P T+ P + P T ++ A T T Sbjct: 273 PTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTT 332 Query: 281 TAELVVIEDAAE--PKEPAPPNGSAAEPPTEAASREENQAGPEATTSDP 327 + ++ A PK+PAP P T P TT +P Sbjct: 333 KSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEP 381 >gi|189181720 proteoglycan 4 isoform B [Homo sapiens] Length = 1363 Score = 46.6 bits (109), Expect = 3e-05 Identities = 58/245 (23%), Positives = 87/245 (35%), Gaps = 21/245 (8%) Query: 102 DSAPATAKENA------AAPSPVRAPAPSPAKEERKTEVVMNSQQTPVGTPKDKRVSNTP 155 + AP T KE A AP+ ++ PAP+ K+ E+ + + P T DK TP Sbjct: 654 EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTP 713 Query: 156 LRTVDGSPMMKAVVHAVD--GTAENGIHPLSSSEVDELIHKADEVTLSEAGSTAGAAETR 213 T +P A + T G P + E K + E T T Sbjct: 714 KGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPK--KPAPKELAPTTTKGPTS 771 Query: 214 GAVEGAARTTPSRREITGVQAQPGEATSGPPGIQPGQEPPVTMIFMGYQNVEDEAETKKV 273 + A TTP T +P T P + PP T + E T Sbjct: 772 TTSDKPAPTTPKETAPT-TPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHK 830 Query: 274 LGLQDT--ITAELVVIEDAAEPKEPAPP---NGSAAEPPTEAASREEN-----QAGPEAT 323 + T ++AE PKEP P +A +P ++++ + PE T Sbjct: 831 SPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETT 890 Query: 324 TSDPQ 328 T+ P+ Sbjct: 891 TAAPK 895 Score = 41.6 bits (96), Expect = 0.001 Identities = 57/227 (25%), Positives = 72/227 (31%), Gaps = 23/227 (10%) Query: 103 SAPATAKENAAAPSPVRAPAPSPAKEERKT---EVVMNSQQTPVGTPKDKRVSNTPLRTV 159 SAP T KE AP+ + PAP+ KE T E + ++ TPK+ TP + Sbjct: 347 SAPTTPKE--PAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEP-APTTPKKPA 403 Query: 160 DGSPMMKAVVHAVDGTAENGIHPLSSSEVDELIHKADEVTLSEAGSTAGAAETRGAVEGA 219 +P A P + E K T E T A + Sbjct: 404 PTTPKEPA--------------PTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKP 449 Query: 220 ARTTPSRREITGVQAQPGEATSGPPGIQPGQEPPVTMIFMGYQNVEDEAETKKVLGLQDT 279 A TTP T + T P P + P T E T K Sbjct: 450 APTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPK 509 Query: 280 ITAELVVIEDA-AEPKEPAP--PNGSAAEPPTEAASREENQAGPEAT 323 + E A PKEPAP P A P E A + P T Sbjct: 510 EPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT 556 Score = 35.0 bits (79), Expect = 0.098 Identities = 63/244 (25%), Positives = 85/244 (34%), Gaps = 29/244 (11%) Query: 102 DSAPATAKENAAAPSPVRAPAPSPAKEERKTEVVMNSQQTP---VGTPKDKRVSNTPLRT 158 + AP T KE AP+ + PAP+ KE T + TP T +K TP + Sbjct: 542 EPAPTTPKE--PAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKP 599 Query: 159 VDGSPMMKAVVHAVDGTAENGIHPLSSSEVDELIHKADE---VTLSEAGSTAGAAETRGA 215 +P A + T P ++ + E T E T Sbjct: 600 APTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT 659 Query: 216 VEGAARTTPSRREITGVQAQPGEATSGPPGIQPGQEPPVTMIFMGYQNVEDEAETKKVLG 275 + A TTP T ++ +P T P P + P T + A T G Sbjct: 660 PKETAPTTPKGTAPTTLK-EPAPTTPKKPA--PKELAPTTTKEPTSTTCDKPAPTTP-KG 715 Query: 276 LQDTITAELVVIEDAAEPKEPAP--PNGSA----AEP----PTEAASRE---ENQAGPEA 322 T E PKEPAP P G+A EP P + A +E GP + Sbjct: 716 TAPTTPKE----PAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTS 771 Query: 323 TTSD 326 TTSD Sbjct: 772 TTSD 775 Score = 34.3 bits (77), Expect = 0.17 Identities = 58/228 (25%), Positives = 73/228 (32%), Gaps = 30/228 (13%) Query: 105 PATAKENAAAPSPVRAPAPSPAKEERKTEVVMNSQQTPVGTPKDKRVSNTPLRTVDGSPM 164 PA AAAP+ + PAP+ KE T TPK+ TP T +P Sbjct: 623 PAPTTPKAAAPNTPKEPAPTTPKEPAPT------------TPKEP-APTTPKETAPTTP- 668 Query: 165 MKAVVHAVDGTAENGI-HPLSSSEVDELIHKADEVTLSEAGSTAGAAETRGAVEGAARTT 223 GTA + P ++ + T E ST +G A TT Sbjct: 669 --------KGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTT 720 Query: 224 PSRREITGVQAQPGEATSGPPGIQPG--QEPPVTMIFMGYQNVEDEAETKKVLGLQDTIT 281 P T +P T P G P +EP T TK Sbjct: 721 PKEPAPT-TPKEPAPTT--PKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKP 777 Query: 282 AELVVIEDA-AEPKEPAPPNGSAAEPPT-EAASREENQAGPEATTSDP 327 A E A PKEPAP P T E ++ TT +P Sbjct: 778 APTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEP 825 Score = 31.2 bits (69), Expect = 1.4 Identities = 52/232 (22%), Positives = 74/232 (31%), Gaps = 28/232 (12%) Query: 102 DSAPATAKENAA------APSPVRAPAPSPAKEERKTEVVMNSQQTPVGTPKDKRVSNTP 155 + AP T KE A AP+ + PAP+ KE T + + P T + TP Sbjct: 518 EPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPT-----TTKKPAPTTPKEPAPTTP 572 Query: 156 LRTVDGSPMMKAVVHAVDGTAENGIHPLSSSEVDELIHKADE----VTLSEAGSTAGAAE 211 T +P K + A + + +EL E T E T A Sbjct: 573 KETAPTTP-KKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAA 631 Query: 212 TRGAVEGAARTTPSRREITGVQAQPGEATSGPPG-IQPGQEPPVTMIFMGYQNVEDEAET 270 + A TTP +P T P P + P T +++ A T Sbjct: 632 APNTPKEPAPTTPK---------EPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPT 682 Query: 271 --KKVLGLQDTITAELVVIEDAAEPKEPAPPNGSAAEPPTEAASREENQAGP 320 KK + T + P P G+A P E A + P Sbjct: 683 TPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAP 734 Score = 28.5 bits (62), Expect = 9.1 Identities = 49/229 (21%), Positives = 83/229 (36%), Gaps = 15/229 (6%) Query: 109 KENAAAPSPVRAPAPSPAKEERKTEVVMNSQQTPVGTPKDKRVSNTPLRTVDGSPMMKAV 168 K A P R P + ++T + +N ++T V T K+ +N T DG + Sbjct: 210 KITTAKPINPRPSLPPNSDTSKETSLTVN-KETTVET-KETTTTNKQTST-DGKEKTTSA 266 Query: 169 --VHAVDGTAENGIHPLSSSEVDELIHKADEVTLSEAGSTAGAAETRGAVEGAARTTPSR 226 +++ T+ + P +S + + KA+ T A +T T + A TTP Sbjct: 267 KETQSIEKTSAKDLAP-TSKVLAKPTPKAETTTKGPALTTP-KEPTPTTPKEPASTTPKE 324 Query: 227 REITGVQA------QPGEATSGPPGIQPGQEPPVTMIFMGYQNVEDEAETKKVLGLQDTI 280 T +++ +P T+ P + P T ++ A T T Sbjct: 325 PTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTT 384 Query: 281 TAELVVIEDAAE--PKEPAPPNGSAAEPPTEAASREENQAGPEATTSDP 327 + ++ A PK+PAP P T P TT +P Sbjct: 385 KSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEP 433 >gi|67190163 proteoglycan 4 isoform A [Homo sapiens] Length = 1404 Score = 46.6 bits (109), Expect = 3e-05 Identities = 58/245 (23%), Positives = 87/245 (35%), Gaps = 21/245 (8%) Query: 102 DSAPATAKENA------AAPSPVRAPAPSPAKEERKTEVVMNSQQTPVGTPKDKRVSNTP 155 + AP T KE A AP+ ++ PAP+ K+ E+ + + P T DK TP Sbjct: 695 EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTP 754 Query: 156 LRTVDGSPMMKAVVHAVD--GTAENGIHPLSSSEVDELIHKADEVTLSEAGSTAGAAETR 213 T +P A + T G P + E K + E T T Sbjct: 755 KGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPK--KPAPKELAPTTTKGPTS 812 Query: 214 GAVEGAARTTPSRREITGVQAQPGEATSGPPGIQPGQEPPVTMIFMGYQNVEDEAETKKV 273 + A TTP T +P T P + PP T + E T Sbjct: 813 TTSDKPAPTTPKETAPT-TPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHK 871 Query: 274 LGLQDT--ITAELVVIEDAAEPKEPAPP---NGSAAEPPTEAASREEN-----QAGPEAT 323 + T ++AE PKEP P +A +P ++++ + PE T Sbjct: 872 SPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETT 931 Query: 324 TSDPQ 328 T+ P+ Sbjct: 932 TAAPK 936 Score = 41.6 bits (96), Expect = 0.001 Identities = 57/227 (25%), Positives = 72/227 (31%), Gaps = 23/227 (10%) Query: 103 SAPATAKENAAAPSPVRAPAPSPAKEERKT---EVVMNSQQTPVGTPKDKRVSNTPLRTV 159 SAP T KE AP+ + PAP+ KE T E + ++ TPK+ TP + Sbjct: 388 SAPTTPKE--PAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEP-APTTPKKPA 444 Query: 160 DGSPMMKAVVHAVDGTAENGIHPLSSSEVDELIHKADEVTLSEAGSTAGAAETRGAVEGA 219 +P A P + E K T E T A + Sbjct: 445 PTTPKEPA--------------PTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKP 490 Query: 220 ARTTPSRREITGVQAQPGEATSGPPGIQPGQEPPVTMIFMGYQNVEDEAETKKVLGLQDT 279 A TTP T + T P P + P T E T K Sbjct: 491 APTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPK 550 Query: 280 ITAELVVIEDA-AEPKEPAP--PNGSAAEPPTEAASREENQAGPEAT 323 + E A PKEPAP P A P E A + P T Sbjct: 551 EPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT 597 Score = 35.0 bits (79), Expect = 0.098 Identities = 63/244 (25%), Positives = 85/244 (34%), Gaps = 29/244 (11%) Query: 102 DSAPATAKENAAAPSPVRAPAPSPAKEERKTEVVMNSQQTP---VGTPKDKRVSNTPLRT 158 + AP T KE AP+ + PAP+ KE T + TP T +K TP + Sbjct: 583 EPAPTTPKE--PAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKP 640 Query: 159 VDGSPMMKAVVHAVDGTAENGIHPLSSSEVDELIHKADE---VTLSEAGSTAGAAETRGA 215 +P A + T P ++ + E T E T Sbjct: 641 APTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT 700 Query: 216 VEGAARTTPSRREITGVQAQPGEATSGPPGIQPGQEPPVTMIFMGYQNVEDEAETKKVLG 275 + A TTP T ++ +P T P P + P T + A T G Sbjct: 701 PKETAPTTPKGTAPTTLK-EPAPTTPKKPA--PKELAPTTTKEPTSTTCDKPAPTTP-KG 756 Query: 276 LQDTITAELVVIEDAAEPKEPAP--PNGSA----AEP----PTEAASRE---ENQAGPEA 322 T E PKEPAP P G+A EP P + A +E GP + Sbjct: 757 TAPTTPKE----PAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTS 812 Query: 323 TTSD 326 TTSD Sbjct: 813 TTSD 816 Score = 34.3 bits (77), Expect = 0.17 Identities = 58/228 (25%), Positives = 73/228 (32%), Gaps = 30/228 (13%) Query: 105 PATAKENAAAPSPVRAPAPSPAKEERKTEVVMNSQQTPVGTPKDKRVSNTPLRTVDGSPM 164 PA AAAP+ + PAP+ KE T TPK+ TP T +P Sbjct: 664 PAPTTPKAAAPNTPKEPAPTTPKEPAPT------------TPKEP-APTTPKETAPTTP- 709 Query: 165 MKAVVHAVDGTAENGI-HPLSSSEVDELIHKADEVTLSEAGSTAGAAETRGAVEGAARTT 223 GTA + P ++ + T E ST +G A TT Sbjct: 710 --------KGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTT 761 Query: 224 PSRREITGVQAQPGEATSGPPGIQPG--QEPPVTMIFMGYQNVEDEAETKKVLGLQDTIT 281 P T +P T P G P +EP T TK Sbjct: 762 PKEPAPT-TPKEPAPTT--PKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKP 818 Query: 282 AELVVIEDA-AEPKEPAPPNGSAAEPPT-EAASREENQAGPEATTSDP 327 A E A PKEPAP P T E ++ TT +P Sbjct: 819 APTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEP 866 Score = 31.2 bits (69), Expect = 1.4 Identities = 52/232 (22%), Positives = 74/232 (31%), Gaps = 28/232 (12%) Query: 102 DSAPATAKENAA------APSPVRAPAPSPAKEERKTEVVMNSQQTPVGTPKDKRVSNTP 155 + AP T KE A AP+ + PAP+ KE T + + P T + TP Sbjct: 559 EPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPT-----TTKKPAPTTPKEPAPTTP 613 Query: 156 LRTVDGSPMMKAVVHAVDGTAENGIHPLSSSEVDELIHKADE----VTLSEAGSTAGAAE 211 T +P K + A + + +EL E T E T A Sbjct: 614 KETAPTTP-KKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAA 672 Query: 212 TRGAVEGAARTTPSRREITGVQAQPGEATSGPPG-IQPGQEPPVTMIFMGYQNVEDEAET 270 + A TTP +P T P P + P T +++ A T Sbjct: 673 APNTPKEPAPTTPK---------EPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPT 723 Query: 271 --KKVLGLQDTITAELVVIEDAAEPKEPAPPNGSAAEPPTEAASREENQAGP 320 KK + T + P P G+A P E A + P Sbjct: 724 TPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAP 775 Score = 28.5 bits (62), Expect = 9.1 Identities = 49/229 (21%), Positives = 83/229 (36%), Gaps = 15/229 (6%) Query: 109 KENAAAPSPVRAPAPSPAKEERKTEVVMNSQQTPVGTPKDKRVSNTPLRTVDGSPMMKAV 168 K A P R P + ++T + +N ++T V T K+ +N T DG + Sbjct: 251 KITTAKPINPRPSLPPNSDTSKETSLTVN-KETTVET-KETTTTNKQTST-DGKEKTTSA 307 Query: 169 --VHAVDGTAENGIHPLSSSEVDELIHKADEVTLSEAGSTAGAAETRGAVEGAARTTPSR 226 +++ T+ + P +S + + KA+ T A +T T + A TTP Sbjct: 308 KETQSIEKTSAKDLAP-TSKVLAKPTPKAETTTKGPALTTP-KEPTPTTPKEPASTTPKE 365 Query: 227 REITGVQA------QPGEATSGPPGIQPGQEPPVTMIFMGYQNVEDEAETKKVLGLQDTI 280 T +++ +P T+ P + P T ++ A T T Sbjct: 366 PTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTT 425 Query: 281 TAELVVIEDAAE--PKEPAPPNGSAAEPPTEAASREENQAGPEATTSDP 327 + ++ A PK+PAP P T P TT +P Sbjct: 426 KSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEP 474 >gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo sapiens] Length = 1972 Score = 45.8 bits (107), Expect = 6e-05 Identities = 28/105 (26%), Positives = 53/105 (50%) Query: 4 LAAETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSA 63 +A+ ++ Q+ + + E+ +++ + K RQLE+ER LQ + + + LE S+ Sbjct: 1310 VASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTL 1369 Query: 64 SEGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATA 108 + D ++++QD LE+ R +KEIE L + A A Sbjct: 1370 NIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAA 1414 Score = 35.8 bits (81), Expect = 0.057 Identities = 30/110 (27%), Positives = 56/110 (50%), Gaps = 10/110 (9%) Query: 7 ETTSQQERLQA----IAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSS 62 + T Q+E +QA + + ++RQ + EN+ ++LE + QL K+ L+E+ L+ Sbjct: 846 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKN-LLQEQ--LQAETEL 902 Query: 63 ASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENA 112 +E +E R ++ +L + +RLE+E +RG A K+ A Sbjct: 903 YAEAEEMRVRLAAKKQELEEILHEMEARLEEE---EDRGQQLQAERKKMA 949 Score = 34.3 bits (77), Expect = 0.17 Identities = 27/118 (22%), Positives = 58/118 (49%), Gaps = 16/118 (13%) Query: 2 EVLAAETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPS 61 E + E +Q +++ +K K+ EI Q+EDER+ + K +A Sbjct: 1828 EQVEQEAREKQAATKSLKQKDKKLKEI---LLQVEDERKMAEQYKEQA-----------E 1873 Query: 62 SASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAAPSPVR 119 + + L+RQ+++ E++++ + + +L++E++ E +S A +E A S +R Sbjct: 1874 KGNARVKQLKRQLEEAEEESQRINANRRKLQRELD--EATESNEAMGREVNALKSKLR 1929 Score = 33.9 bits (76), Expect = 0.22 Identities = 24/82 (29%), Positives = 40/82 (48%), Gaps = 4/82 (4%) Query: 14 RLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSASEGDEDL--- 70 R +AI + RK QA++++ +R+LED R + + A + + + EDL Sbjct: 1640 REEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAA 1699 Query: 71 -RRQMQDDEQKTRLLEDSVSRL 91 R + Q D +K L E+ S L Sbjct: 1700 ERARKQADLEKEELAEELASSL 1721 Score = 33.5 bits (75), Expect = 0.28 Identities = 23/90 (25%), Positives = 44/90 (48%), Gaps = 3/90 (3%) Query: 21 KRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSASEGDEDLRRQMQDDEQK 80 KR + ++E + QLE+ +LQ + LR L + + + DL+ + + +E+K Sbjct: 1534 KRALETQMEEMKTQLEELEDELQATEDAKLR---LEVNMQALKGQFERDLQARDEQNEEK 1590 Query: 81 TRLLEDSVSRLEKEIEVLERGDSAPATAKE 110 R L+ + E E+E + + A AK+ Sbjct: 1591 RRQLQRQLHEYETELEDERKQRALAAAAKK 1620 Score = 31.6 bits (70), Expect = 1.1 Identities = 19/84 (22%), Positives = 41/84 (48%) Query: 16 QAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSASEGDEDLRRQMQ 75 +A+ E + + E+E + L+ E L K + LE + + E+++ Q++ Sbjct: 1490 RALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLE 1549 Query: 76 DDEQKTRLLEDSVSRLEKEIEVLE 99 + E + + ED+ RLE ++ L+ Sbjct: 1550 ELEDELQATEDAKLRLEVNMQALK 1573 Score = 31.6 bits (70), Expect = 1.1 Identities = 33/137 (24%), Positives = 61/137 (44%), Gaps = 21/137 (15%) Query: 2 EVLAAETTSQQERLQAIA-EKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLE--- 57 E LA E S A+ EKR+ +A I +LE+E+ ++ + + + E Sbjct: 1711 EELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLS 1770 Query: 58 ---GTPSSASEGDEDLRRQM--QDDEQKTRLLE----------DSVSRLEKEIEVLERGD 102 T S ++ +E R+Q+ Q+ E +++L E +++ LE +I LE + Sbjct: 1771 NELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLE--E 1828 Query: 103 SAPATAKENAAAPSPVR 119 A+E AA ++ Sbjct: 1829 QVEQEAREKQAATKSLK 1845 Score = 31.2 bits (69), Expect = 1.4 Identities = 29/112 (25%), Positives = 54/112 (48%), Gaps = 14/112 (12%) Query: 2 EVLAAETT----SQQERLQAIAEKRKRQA---EIENKRRQLEDERRQLQHLKSKALRERW 54 E L AET +++ R++ A+K++ + E+E + + ED +QLQ + K ++ Sbjct: 894 EQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQML 953 Query: 55 LLEGTPSSASEGDEDLRRQMQDDEQKTRLLEDSV-------SRLEKEIEVLE 99 LE + L+ + E K + LED + ++L KE ++LE Sbjct: 954 DLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLE 1005 Score = 30.8 bits (68), Expect = 1.8 Identities = 32/105 (30%), Positives = 49/105 (46%), Gaps = 12/105 (11%) Query: 12 QERLQAIAEKRKR-QAEIENKRRQLEDERRQ---LQHLKSKALRERWLLEGTPSSASEGD 67 Q R + EKR++ Q ++ +LEDER+Q K K + LE SA +G Sbjct: 1581 QARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGR 1640 Query: 68 EDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERG-DSAPATAKEN 111 E+ +Q+ R L+ + ++E+E D ATAKEN Sbjct: 1641 EEAIKQL-------RKLQAQMKDFQRELEDARASRDEIFATAKEN 1678 Score = 28.5 bits (62), Expect = 9.1 Identities = 29/97 (29%), Positives = 48/97 (49%), Gaps = 9/97 (9%) Query: 5 AAETTSQQERLQA-IAEKR----KRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGT 59 A++ Q LQA IAE + K++ E++ +L+DE Q K+ AL++ LEG Sbjct: 1064 ASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQ----KNNALKKIRELEGH 1119 Query: 60 PSSASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIE 96 S E + R E++ R L + + L+ E+E Sbjct: 1120 ISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELE 1156 >gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo sapiens] Length = 1979 Score = 45.8 bits (107), Expect = 6e-05 Identities = 28/105 (26%), Positives = 53/105 (50%) Query: 4 LAAETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSA 63 +A+ ++ Q+ + + E+ +++ + K RQLE+ER LQ + + + LE S+ Sbjct: 1317 VASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTL 1376 Query: 64 SEGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATA 108 + D ++++QD LE+ R +KEIE L + A A Sbjct: 1377 NIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAA 1421 Score = 35.8 bits (81), Expect = 0.057 Identities = 30/110 (27%), Positives = 56/110 (50%), Gaps = 10/110 (9%) Query: 7 ETTSQQERLQA----IAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSS 62 + T Q+E +QA + + ++RQ + EN+ ++LE + QL K+ L+E+ L+ Sbjct: 853 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKN-LLQEQ--LQAETEL 909 Query: 63 ASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENA 112 +E +E R ++ +L + +RLE+E +RG A K+ A Sbjct: 910 YAEAEEMRVRLAAKKQELEEILHEMEARLEEE---EDRGQQLQAERKKMA 956 Score = 34.3 bits (77), Expect = 0.17 Identities = 27/118 (22%), Positives = 58/118 (49%), Gaps = 16/118 (13%) Query: 2 EVLAAETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPS 61 E + E +Q +++ +K K+ EI Q+EDER+ + K +A Sbjct: 1835 EQVEQEAREKQAATKSLKQKDKKLKEI---LLQVEDERKMAEQYKEQA-----------E 1880 Query: 62 SASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAAPSPVR 119 + + L+RQ+++ E++++ + + +L++E++ E +S A +E A S +R Sbjct: 1881 KGNARVKQLKRQLEEAEEESQRINANRRKLQRELD--EATESNEAMGREVNALKSKLR 1936 Score = 33.9 bits (76), Expect = 0.22 Identities = 24/82 (29%), Positives = 40/82 (48%), Gaps = 4/82 (4%) Query: 14 RLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSASEGDEDL--- 70 R +AI + RK QA++++ +R+LED R + + A + + + EDL Sbjct: 1647 REEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAA 1706 Query: 71 -RRQMQDDEQKTRLLEDSVSRL 91 R + Q D +K L E+ S L Sbjct: 1707 ERARKQADLEKEELAEELASSL 1728 Score = 33.5 bits (75), Expect = 0.28 Identities = 23/90 (25%), Positives = 44/90 (48%), Gaps = 3/90 (3%) Query: 21 KRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSASEGDEDLRRQMQDDEQK 80 KR + ++E + QLE+ +LQ + LR L + + + DL+ + + +E+K Sbjct: 1541 KRALETQMEEMKTQLEELEDELQATEDAKLR---LEVNMQALKGQFERDLQARDEQNEEK 1597 Query: 81 TRLLEDSVSRLEKEIEVLERGDSAPATAKE 110 R L+ + E E+E + + A AK+ Sbjct: 1598 RRQLQRQLHEYETELEDERKQRALAAAAKK 1627 Score = 31.6 bits (70), Expect = 1.1 Identities = 19/84 (22%), Positives = 41/84 (48%) Query: 16 QAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSASEGDEDLRRQMQ 75 +A+ E + + E+E + L+ E L K + LE + + E+++ Q++ Sbjct: 1497 RALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLE 1556 Query: 76 DDEQKTRLLEDSVSRLEKEIEVLE 99 + E + + ED+ RLE ++ L+ Sbjct: 1557 ELEDELQATEDAKLRLEVNMQALK 1580 Score = 31.6 bits (70), Expect = 1.1 Identities = 33/137 (24%), Positives = 61/137 (44%), Gaps = 21/137 (15%) Query: 2 EVLAAETTSQQERLQAIA-EKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLE--- 57 E LA E S A+ EKR+ +A I +LE+E+ ++ + + + E Sbjct: 1718 EELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLS 1777 Query: 58 ---GTPSSASEGDEDLRRQM--QDDEQKTRLLE----------DSVSRLEKEIEVLERGD 102 T S ++ +E R+Q+ Q+ E +++L E +++ LE +I LE + Sbjct: 1778 NELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLE--E 1835 Query: 103 SAPATAKENAAAPSPVR 119 A+E AA ++ Sbjct: 1836 QVEQEAREKQAATKSLK 1852 Score = 31.2 bits (69), Expect = 1.4 Identities = 29/112 (25%), Positives = 54/112 (48%), Gaps = 14/112 (12%) Query: 2 EVLAAETT----SQQERLQAIAEKRKRQA---EIENKRRQLEDERRQLQHLKSKALRERW 54 E L AET +++ R++ A+K++ + E+E + + ED +QLQ + K ++ Sbjct: 901 EQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQML 960 Query: 55 LLEGTPSSASEGDEDLRRQMQDDEQKTRLLEDSV-------SRLEKEIEVLE 99 LE + L+ + E K + LED + ++L KE ++LE Sbjct: 961 DLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLE 1012 Score = 30.8 bits (68), Expect = 1.8 Identities = 32/105 (30%), Positives = 49/105 (46%), Gaps = 12/105 (11%) Query: 12 QERLQAIAEKRKR-QAEIENKRRQLEDERRQ---LQHLKSKALRERWLLEGTPSSASEGD 67 Q R + EKR++ Q ++ +LEDER+Q K K + LE SA +G Sbjct: 1588 QARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGR 1647 Query: 68 EDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERG-DSAPATAKEN 111 E+ +Q+ R L+ + ++E+E D ATAKEN Sbjct: 1648 EEAIKQL-------RKLQAQMKDFQRELEDARASRDEIFATAKEN 1685 Score = 28.5 bits (62), Expect = 9.1 Identities = 29/97 (29%), Positives = 48/97 (49%), Gaps = 9/97 (9%) Query: 5 AAETTSQQERLQA-IAEKR----KRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGT 59 A++ Q LQA IAE + K++ E++ +L+DE Q K+ AL++ LEG Sbjct: 1071 ASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQ----KNNALKKIRELEGH 1126 Query: 60 PSSASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIE 96 S E + R E++ R L + + L+ E+E Sbjct: 1127 ISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELE 1163 >gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo sapiens] Length = 1945 Score = 45.8 bits (107), Expect = 6e-05 Identities = 28/105 (26%), Positives = 53/105 (50%) Query: 4 LAAETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSA 63 +A+ ++ Q+ + + E+ +++ + K RQLE+ER LQ + + + LE S+ Sbjct: 1317 VASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTL 1376 Query: 64 SEGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATA 108 + D ++++QD LE+ R +KEIE L + A A Sbjct: 1377 NIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAA 1421 Score = 39.7 bits (91), Expect = 0.004 Identities = 29/127 (22%), Positives = 61/127 (48%), Gaps = 16/127 (12%) Query: 2 EVLAAETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPS 61 E + E +Q +++ +K K+ EI Q+EDER+ + K +A Sbjct: 1835 EQVEQEAREKQAATKSLKQKDKKLKEI---LLQVEDERKMAEQYKEQA-----------E 1880 Query: 62 SASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAAPSPVRAP 121 + + L+RQ+++ E++++ + + +L++E++ E +S A +E A S +R P Sbjct: 1881 KGNARVKQLKRQLEEAEEESQRINANRRKLQRELD--EATESNEAMGREVNALKSKLRGP 1938 Query: 122 APSPAKE 128 P + Sbjct: 1939 PPQETSQ 1945 Score = 35.8 bits (81), Expect = 0.057 Identities = 30/110 (27%), Positives = 56/110 (50%), Gaps = 10/110 (9%) Query: 7 ETTSQQERLQA----IAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSS 62 + T Q+E +QA + + ++RQ + EN+ ++LE + QL K+ L+E+ L+ Sbjct: 853 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKN-LLQEQ--LQAETEL 909 Query: 63 ASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENA 112 +E +E R ++ +L + +RLE+E +RG A K+ A Sbjct: 910 YAEAEEMRVRLAAKKQELEEILHEMEARLEEE---EDRGQQLQAERKKMA 956 Score = 33.9 bits (76), Expect = 0.22 Identities = 24/82 (29%), Positives = 40/82 (48%), Gaps = 4/82 (4%) Query: 14 RLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSASEGDEDL--- 70 R +AI + RK QA++++ +R+LED R + + A + + + EDL Sbjct: 1647 REEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAA 1706 Query: 71 -RRQMQDDEQKTRLLEDSVSRL 91 R + Q D +K L E+ S L Sbjct: 1707 ERARKQADLEKEELAEELASSL 1728 Score = 33.5 bits (75), Expect = 0.28 Identities = 23/90 (25%), Positives = 44/90 (48%), Gaps = 3/90 (3%) Query: 21 KRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSASEGDEDLRRQMQDDEQK 80 KR + ++E + QLE+ +LQ + LR L + + + DL+ + + +E+K Sbjct: 1541 KRALETQMEEMKTQLEELEDELQATEDAKLR---LEVNMQALKGQFERDLQARDEQNEEK 1597 Query: 81 TRLLEDSVSRLEKEIEVLERGDSAPATAKE 110 R L+ + E E+E + + A AK+ Sbjct: 1598 RRQLQRQLHEYETELEDERKQRALAAAAKK 1627 Score = 31.6 bits (70), Expect = 1.1 Identities = 19/84 (22%), Positives = 41/84 (48%) Query: 16 QAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSASEGDEDLRRQMQ 75 +A+ E + + E+E + L+ E L K + LE + + E+++ Q++ Sbjct: 1497 RALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLE 1556 Query: 76 DDEQKTRLLEDSVSRLEKEIEVLE 99 + E + + ED+ RLE ++ L+ Sbjct: 1557 ELEDELQATEDAKLRLEVNMQALK 1580 Score = 31.6 bits (70), Expect = 1.1 Identities = 33/137 (24%), Positives = 61/137 (44%), Gaps = 21/137 (15%) Query: 2 EVLAAETTSQQERLQAIA-EKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLE--- 57 E LA E S A+ EKR+ +A I +LE+E+ ++ + + + E Sbjct: 1718 EELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLS 1777 Query: 58 ---GTPSSASEGDEDLRRQM--QDDEQKTRLLE----------DSVSRLEKEIEVLERGD 102 T S ++ +E R+Q+ Q+ E +++L E +++ LE +I LE + Sbjct: 1778 NELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLE--E 1835 Query: 103 SAPATAKENAAAPSPVR 119 A+E AA ++ Sbjct: 1836 QVEQEAREKQAATKSLK 1852 Score = 31.2 bits (69), Expect = 1.4 Identities = 29/112 (25%), Positives = 54/112 (48%), Gaps = 14/112 (12%) Query: 2 EVLAAETT----SQQERLQAIAEKRKRQA---EIENKRRQLEDERRQLQHLKSKALRERW 54 E L AET +++ R++ A+K++ + E+E + + ED +QLQ + K ++ Sbjct: 901 EQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQML 960 Query: 55 LLEGTPSSASEGDEDLRRQMQDDEQKTRLLEDSV-------SRLEKEIEVLE 99 LE + L+ + E K + LED + ++L KE ++LE Sbjct: 961 DLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLE 1012 Score = 30.8 bits (68), Expect = 1.8 Identities = 32/105 (30%), Positives = 49/105 (46%), Gaps = 12/105 (11%) Query: 12 QERLQAIAEKRKR-QAEIENKRRQLEDERRQ---LQHLKSKALRERWLLEGTPSSASEGD 67 Q R + EKR++ Q ++ +LEDER+Q K K + LE SA +G Sbjct: 1588 QARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGR 1647 Query: 68 EDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERG-DSAPATAKEN 111 E+ +Q+ R L+ + ++E+E D ATAKEN Sbjct: 1648 EEAIKQL-------RKLQAQMKDFQRELEDARASRDEIFATAKEN 1685 Score = 28.5 bits (62), Expect = 9.1 Identities = 29/97 (29%), Positives = 48/97 (49%), Gaps = 9/97 (9%) Query: 5 AAETTSQQERLQA-IAEKR----KRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGT 59 A++ Q LQA IAE + K++ E++ +L+DE Q K+ AL++ LEG Sbjct: 1071 ASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQ----KNNALKKIRELEGH 1126 Query: 60 PSSASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIE 96 S E + R E++ R L + + L+ E+E Sbjct: 1127 ISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELE 1163 >gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo sapiens] Length = 1938 Score = 45.8 bits (107), Expect = 6e-05 Identities = 28/105 (26%), Positives = 53/105 (50%) Query: 4 LAAETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSA 63 +A+ ++ Q+ + + E+ +++ + K RQLE+ER LQ + + + LE S+ Sbjct: 1310 VASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTL 1369 Query: 64 SEGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATA 108 + D ++++QD LE+ R +KEIE L + A A Sbjct: 1370 NIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAA 1414 Score = 39.7 bits (91), Expect = 0.004 Identities = 29/127 (22%), Positives = 61/127 (48%), Gaps = 16/127 (12%) Query: 2 EVLAAETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPS 61 E + E +Q +++ +K K+ EI Q+EDER+ + K +A Sbjct: 1828 EQVEQEAREKQAATKSLKQKDKKLKEI---LLQVEDERKMAEQYKEQA-----------E 1873 Query: 62 SASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAAPSPVRAP 121 + + L+RQ+++ E++++ + + +L++E++ E +S A +E A S +R P Sbjct: 1874 KGNARVKQLKRQLEEAEEESQRINANRRKLQRELD--EATESNEAMGREVNALKSKLRGP 1931 Query: 122 APSPAKE 128 P + Sbjct: 1932 PPQETSQ 1938 Score = 35.8 bits (81), Expect = 0.057 Identities = 30/110 (27%), Positives = 56/110 (50%), Gaps = 10/110 (9%) Query: 7 ETTSQQERLQA----IAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSS 62 + T Q+E +QA + + ++RQ + EN+ ++LE + QL K+ L+E+ L+ Sbjct: 846 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKN-LLQEQ--LQAETEL 902 Query: 63 ASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENA 112 +E +E R ++ +L + +RLE+E +RG A K+ A Sbjct: 903 YAEAEEMRVRLAAKKQELEEILHEMEARLEEE---EDRGQQLQAERKKMA 949 Score = 33.9 bits (76), Expect = 0.22 Identities = 24/82 (29%), Positives = 40/82 (48%), Gaps = 4/82 (4%) Query: 14 RLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSASEGDEDL--- 70 R +AI + RK QA++++ +R+LED R + + A + + + EDL Sbjct: 1640 REEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAA 1699 Query: 71 -RRQMQDDEQKTRLLEDSVSRL 91 R + Q D +K L E+ S L Sbjct: 1700 ERARKQADLEKEELAEELASSL 1721 Score = 33.5 bits (75), Expect = 0.28 Identities = 23/90 (25%), Positives = 44/90 (48%), Gaps = 3/90 (3%) Query: 21 KRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSASEGDEDLRRQMQDDEQK 80 KR + ++E + QLE+ +LQ + LR L + + + DL+ + + +E+K Sbjct: 1534 KRALETQMEEMKTQLEELEDELQATEDAKLR---LEVNMQALKGQFERDLQARDEQNEEK 1590 Query: 81 TRLLEDSVSRLEKEIEVLERGDSAPATAKE 110 R L+ + E E+E + + A AK+ Sbjct: 1591 RRQLQRQLHEYETELEDERKQRALAAAAKK 1620 Score = 31.6 bits (70), Expect = 1.1 Identities = 19/84 (22%), Positives = 41/84 (48%) Query: 16 QAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSASEGDEDLRRQMQ 75 +A+ E + + E+E + L+ E L K + LE + + E+++ Q++ Sbjct: 1490 RALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLE 1549 Query: 76 DDEQKTRLLEDSVSRLEKEIEVLE 99 + E + + ED+ RLE ++ L+ Sbjct: 1550 ELEDELQATEDAKLRLEVNMQALK 1573 Score = 31.6 bits (70), Expect = 1.1 Identities = 33/137 (24%), Positives = 61/137 (44%), Gaps = 21/137 (15%) Query: 2 EVLAAETTSQQERLQAIA-EKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLE--- 57 E LA E S A+ EKR+ +A I +LE+E+ ++ + + + E Sbjct: 1711 EELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLS 1770 Query: 58 ---GTPSSASEGDEDLRRQM--QDDEQKTRLLE----------DSVSRLEKEIEVLERGD 102 T S ++ +E R+Q+ Q+ E +++L E +++ LE +I LE + Sbjct: 1771 NELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLE--E 1828 Query: 103 SAPATAKENAAAPSPVR 119 A+E AA ++ Sbjct: 1829 QVEQEAREKQAATKSLK 1845 Score = 31.2 bits (69), Expect = 1.4 Identities = 29/112 (25%), Positives = 54/112 (48%), Gaps = 14/112 (12%) Query: 2 EVLAAETT----SQQERLQAIAEKRKRQA---EIENKRRQLEDERRQLQHLKSKALRERW 54 E L AET +++ R++ A+K++ + E+E + + ED +QLQ + K ++ Sbjct: 894 EQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQML 953 Query: 55 LLEGTPSSASEGDEDLRRQMQDDEQKTRLLEDSV-------SRLEKEIEVLE 99 LE + L+ + E K + LED + ++L KE ++LE Sbjct: 954 DLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLE 1005 Score = 30.8 bits (68), Expect = 1.8 Identities = 32/105 (30%), Positives = 49/105 (46%), Gaps = 12/105 (11%) Query: 12 QERLQAIAEKRKR-QAEIENKRRQLEDERRQ---LQHLKSKALRERWLLEGTPSSASEGD 67 Q R + EKR++ Q ++ +LEDER+Q K K + LE SA +G Sbjct: 1581 QARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGR 1640 Query: 68 EDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERG-DSAPATAKEN 111 E+ +Q+ R L+ + ++E+E D ATAKEN Sbjct: 1641 EEAIKQL-------RKLQAQMKDFQRELEDARASRDEIFATAKEN 1678 Score = 28.5 bits (62), Expect = 9.1 Identities = 29/97 (29%), Positives = 48/97 (49%), Gaps = 9/97 (9%) Query: 5 AAETTSQQERLQA-IAEKR----KRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGT 59 A++ Q LQA IAE + K++ E++ +L+DE Q K+ AL++ LEG Sbjct: 1064 ASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQ----KNNALKKIRELEGH 1119 Query: 60 PSSASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIE 96 S E + R E++ R L + + L+ E+E Sbjct: 1120 ISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELE 1156 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.305 0.123 0.333 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 14,619,067 Number of Sequences: 37866 Number of extensions: 785741 Number of successful extensions: 9013 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 216 Number of HSP's successfully gapped in prelim test: 777 Number of HSP's that attempted gapping in prelim test: 5950 Number of HSP's gapped (non-prelim): 3056 length of query: 343 length of database: 18,247,518 effective HSP length: 103 effective length of query: 240 effective length of database: 14,347,320 effective search space: 3443356800 effective search space used: 3443356800 T: 11 A: 40 X1: 16 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 43 (22.0 bits) S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.