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Search of human proteins with 91718897
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|91718897 mitogen-activated protein kinase 3 isoform 2 [Homo
sapiens]
(357 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|91718897 mitogen-activated protein kinase 3 isoform 2 [Homo s... 727 0.0
gi|91718899 mitogen-activated protein kinase 3 isoform 1 [Homo s... 692 0.0
gi|158138507 mitogen-activated protein kinase 3 isoform 3 [Homo ... 583 e-167
gi|20986531 mitogen-activated protein kinase 1 [Homo sapiens] 581 e-166
gi|66932916 mitogen-activated protein kinase 1 [Homo sapiens] 581 e-166
gi|20986497 mitogen-activated protein kinase 7 isoform 1 [Homo s... 320 1e-87
gi|209529736 mitogen-activated protein kinase 7 isoform 1 [Homo ... 320 1e-87
gi|209529734 mitogen-activated protein kinase 7 isoform 1 [Homo ... 320 1e-87
gi|20986512 mitogen-activated protein kinase 14 isoform 2 [Homo ... 308 6e-84
gi|4503069 mitogen-activated protein kinase 14 isoform 1 [Homo s... 303 2e-82
gi|20128774 mitogen-activated protein kinase 11 [Homo sapiens] 299 3e-81
gi|4506085 mitogen-activated protein kinase 13 [Homo sapiens] 279 2e-75
gi|48255970 mitogen-activated protein kinase 12 [Homo sapiens] 278 5e-75
gi|20986514 mitogen-activated protein kinase 14 isoform 3 [Homo ... 265 4e-71
gi|21237745 mitogen-activated protein kinase 9 isoform JNK2 beta... 258 6e-69
gi|21237742 mitogen-activated protein kinase 9 isoform JNK2 beta... 258 6e-69
gi|4506081 mitogen-activated protein kinase 10 isoform 1 [Homo s... 256 3e-68
gi|20986510 mitogen-activated protein kinase 10 isoform 2 [Homo ... 256 3e-68
gi|20986506 mitogen-activated protein kinase 10 isoform 3 [Homo ... 256 3e-68
gi|4506091 mitogen-activated protein kinase 6 [Homo sapiens] 255 4e-68
gi|20986523 mitogen-activated protein kinase 8 isoform JNK1 alph... 253 2e-67
gi|4506095 mitogen-activated protein kinase 8 isoform JNK1 alpha... 253 2e-67
gi|89276769 mitogen-activated protein kinase 4 [Homo sapiens] 250 1e-66
gi|20986521 mitogen-activated protein kinase 8 isoform JNK1 beta... 249 2e-66
gi|20986519 mitogen-activated protein kinase 8 isoform JNK1 beta... 249 2e-66
gi|21237739 mitogen-activated protein kinase 9 isoform JNK2 alph... 248 5e-66
gi|21237736 mitogen-activated protein kinase 9 isoform JNK2 alph... 248 5e-66
gi|95147356 mitogen-activated protein kinase 15 [Homo sapiens] 248 6e-66
gi|20986516 mitogen-activated protein kinase 14 isoform 4 [Homo ... 247 1e-65
gi|149408126 nemo like kinase [Homo sapiens] 247 1e-65
>gi|91718897 mitogen-activated protein kinase 3 isoform 2 [Homo
sapiens]
Length = 357
Score = 727 bits (1877), Expect = 0.0
Identities = 357/357 (100%), Positives = 357/357 (100%)
Query: 1 MAAAAAQGGGGGEPRRTEGVGPGVPGEVEMVKGQPFDVGPRYTQLQYIGEGAYGMVSSAY 60
MAAAAAQGGGGGEPRRTEGVGPGVPGEVEMVKGQPFDVGPRYTQLQYIGEGAYGMVSSAY
Sbjct: 1 MAAAAAQGGGGGEPRRTEGVGPGVPGEVEMVKGQPFDVGPRYTQLQYIGEGAYGMVSSAY 60
Query: 61 DHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRASTLEAMRDVYI 120
DHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRASTLEAMRDVYI
Sbjct: 61 DHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRASTLEAMRDVYI 120
Query: 121 VQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDL 180
VQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDL
Sbjct: 121 VQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDL 180
Query: 181 KICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS 240
KICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS
Sbjct: 181 KICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS 240
Query: 241 NRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSD 300
NRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSD
Sbjct: 241 NRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSD 300
Query: 301 SKALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEVGQSPAAVGLGAGEQGGT 357
SKALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEVGQSPAAVGLGAGEQGGT
Sbjct: 301 SKALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEVGQSPAAVGLGAGEQGGT 357
>gi|91718899 mitogen-activated protein kinase 3 isoform 1 [Homo
sapiens]
Length = 379
Score = 692 bits (1787), Expect = 0.0
Identities = 341/345 (98%), Positives = 342/345 (99%), Gaps = 1/345 (0%)
Query: 1 MAAAAAQGGGGGEPRRTEGVGPGVPGEVEMVKGQPFDVGPRYTQLQYIGEGAYGMVSSAY 60
MAAAAAQGGGGGEPRRTEGVGPGVPGEVEMVKGQPFDVGPRYTQLQYIGEGAYGMVSSAY
Sbjct: 1 MAAAAAQGGGGGEPRRTEGVGPGVPGEVEMVKGQPFDVGPRYTQLQYIGEGAYGMVSSAY 60
Query: 61 DHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRASTLEAMRDVYI 120
DHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRASTLEAMRDVYI
Sbjct: 61 DHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRASTLEAMRDVYI 120
Query: 121 VQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDL 180
VQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDL
Sbjct: 121 VQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDL 180
Query: 181 KICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS 240
KICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS
Sbjct: 181 KICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS 240
Query: 241 NRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSD 300
NRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSD
Sbjct: 241 NRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSD 300
Query: 301 SKALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDE-VGQSP 344
SKALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDE V + P
Sbjct: 301 SKALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEEP 345
>gi|158138507 mitogen-activated protein kinase 3 isoform 3 [Homo
sapiens]
Length = 335
Score = 583 bits (1504), Expect = e-167
Identities = 297/345 (86%), Positives = 298/345 (86%), Gaps = 45/345 (13%)
Query: 1 MAAAAAQGGGGGEPRRTEGVGPGVPGEVEMVKGQPFDVGPRYTQLQYIGEGAYGMVSSAY 60
MAAAAAQGGGGGEPRRTEGVGPGVPGEVEMVKGQPFDVGPRYTQLQYIGEGAYGMVSSAY
Sbjct: 1 MAAAAAQGGGGGEPRRTEGVGPGVPGEVEMVKGQPFDVGPRYTQLQYIGEGAYGMVSSAY 60
Query: 61 DHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRASTLEAMRDVYI 120
DHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRASTLEAMRDVYI
Sbjct: 61 DHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRASTLEAMRDVYI 120
Query: 121 VQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDL 180
VQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDL
Sbjct: 121 VQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDL 180
Query: 181 KICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS 240
KICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS
Sbjct: 181 KICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS 240
Query: 241 NRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSD 300
NRPIFPGKHYLDQLNHIL
Sbjct: 241 NRPIFPGKHYLDQLNHIL------------------------------------------ 258
Query: 301 SKALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDE-VGQSP 344
ALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDE V + P
Sbjct: 259 --ALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEEP 301
>gi|20986531 mitogen-activated protein kinase 1 [Homo sapiens]
Length = 360
Score = 581 bits (1498), Expect = e-166
Identities = 285/345 (82%), Positives = 306/345 (88%), Gaps = 18/345 (5%)
Query: 1 MAAAAAQGGGGGEPRRTEGVGPGVPGEVEMVKGQPFDVGPRYTQLQYIGEGAYGMVSSAY 60
MAAAAA G G EMV+GQ FDVGPRYT L YIGEGAYGMV SAY
Sbjct: 1 MAAAAAAGAGP-----------------EMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAY 43
Query: 61 DHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRASTLEAMRDVYI 120
D+V K RVAIKKISPFEHQTYCQRTLREI+ILLRFRHEN+IGI DI+RA T+E M+DVYI
Sbjct: 44 DNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYI 103
Query: 121 VQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDL 180
VQDLMETDLYKLLK+Q LSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLL+NTTCDL
Sbjct: 104 VQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDL 163
Query: 181 KICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS 240
KICDFGLAR+ADP+HDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS
Sbjct: 164 KICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS 223
Query: 241 NRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSD 300
NRPIFPGKHYLDQLNHILGILGSPSQEDLNCIIN+KARNYL SLP K KV W +LFP +D
Sbjct: 224 NRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNAD 283
Query: 301 SKALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDE-VGQSP 344
SKALDLLD+MLTFNP+KRI VE+ALAHPYLEQYYDP+DE + ++P
Sbjct: 284 SKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAP 328
>gi|66932916 mitogen-activated protein kinase 1 [Homo sapiens]
Length = 360
Score = 581 bits (1498), Expect = e-166
Identities = 285/345 (82%), Positives = 306/345 (88%), Gaps = 18/345 (5%)
Query: 1 MAAAAAQGGGGGEPRRTEGVGPGVPGEVEMVKGQPFDVGPRYTQLQYIGEGAYGMVSSAY 60
MAAAAA G G EMV+GQ FDVGPRYT L YIGEGAYGMV SAY
Sbjct: 1 MAAAAAAGAGP-----------------EMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAY 43
Query: 61 DHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRASTLEAMRDVYI 120
D+V K RVAIKKISPFEHQTYCQRTLREI+ILLRFRHEN+IGI DI+RA T+E M+DVYI
Sbjct: 44 DNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYI 103
Query: 121 VQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDL 180
VQDLMETDLYKLLK+Q LSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLL+NTTCDL
Sbjct: 104 VQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDL 163
Query: 181 KICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS 240
KICDFGLAR+ADP+HDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS
Sbjct: 164 KICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS 223
Query: 241 NRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSD 300
NRPIFPGKHYLDQLNHILGILGSPSQEDLNCIIN+KARNYL SLP K KV W +LFP +D
Sbjct: 224 NRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNAD 283
Query: 301 SKALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDE-VGQSP 344
SKALDLLD+MLTFNP+KRI VE+ALAHPYLEQYYDP+DE + ++P
Sbjct: 284 SKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAP 328
>gi|20986497 mitogen-activated protein kinase 7 isoform 1 [Homo
sapiens]
Length = 816
Score = 320 bits (820), Expect = 1e-87
Identities = 162/313 (51%), Positives = 223/313 (71%), Gaps = 4/313 (1%)
Query: 36 FDVGPRYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKI-SPFEHQTYCQRTLREIQILLR 94
FDVG Y ++ IG GAYG+VSSA + +VAIKKI + F+ T +RTLRE++IL
Sbjct: 49 FDVGDEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKH 108
Query: 95 FRHENVIGIRDILRAST-LEAMRDVYIVQDLMETDLYKLLKSQQ-LSNDHICYFLYQILR 152
F+H+N+I I+DILR + + VY+V DLME+DL++++ S Q L+ +H+ YFLYQ+LR
Sbjct: 109 FKHDNIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLR 168
Query: 153 GLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLAR-IADPEHDHTGFLTEYVATRWYR 211
GLKY+HSA V+HRDLKPSNLL+N C+LKI DFG+AR + +H F+TEYVATRWYR
Sbjct: 169 GLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYR 228
Query: 212 APEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNC 271
APE+ML+ YT++ID+WSVGCI EML+ R +FPGK+Y+ QL I+ +LG+PS +
Sbjct: 229 APELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQA 288
Query: 272 IINMKARNYLQSLPSKTKVAWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEALAHPYLE 331
+ + R Y+QSLP + V W ++P +D +AL LL RML F P+ RI+ AL HP+L
Sbjct: 289 VGAERVRAYIQSLPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLA 348
Query: 332 QYYDPTDEVGQSP 344
+Y+DP DE +P
Sbjct: 349 KYHDPDDEPDCAP 361
>gi|209529736 mitogen-activated protein kinase 7 isoform 1 [Homo
sapiens]
Length = 816
Score = 320 bits (820), Expect = 1e-87
Identities = 162/313 (51%), Positives = 223/313 (71%), Gaps = 4/313 (1%)
Query: 36 FDVGPRYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKI-SPFEHQTYCQRTLREIQILLR 94
FDVG Y ++ IG GAYG+VSSA + +VAIKKI + F+ T +RTLRE++IL
Sbjct: 49 FDVGDEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKH 108
Query: 95 FRHENVIGIRDILRAST-LEAMRDVYIVQDLMETDLYKLLKSQQ-LSNDHICYFLYQILR 152
F+H+N+I I+DILR + + VY+V DLME+DL++++ S Q L+ +H+ YFLYQ+LR
Sbjct: 109 FKHDNIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLR 168
Query: 153 GLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLAR-IADPEHDHTGFLTEYVATRWYR 211
GLKY+HSA V+HRDLKPSNLL+N C+LKI DFG+AR + +H F+TEYVATRWYR
Sbjct: 169 GLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYR 228
Query: 212 APEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNC 271
APE+ML+ YT++ID+WSVGCI EML+ R +FPGK+Y+ QL I+ +LG+PS +
Sbjct: 229 APELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQA 288
Query: 272 IINMKARNYLQSLPSKTKVAWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEALAHPYLE 331
+ + R Y+QSLP + V W ++P +D +AL LL RML F P+ RI+ AL HP+L
Sbjct: 289 VGAERVRAYIQSLPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLA 348
Query: 332 QYYDPTDEVGQSP 344
+Y+DP DE +P
Sbjct: 349 KYHDPDDEPDCAP 361
>gi|209529734 mitogen-activated protein kinase 7 isoform 1 [Homo
sapiens]
Length = 816
Score = 320 bits (820), Expect = 1e-87
Identities = 162/313 (51%), Positives = 223/313 (71%), Gaps = 4/313 (1%)
Query: 36 FDVGPRYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKI-SPFEHQTYCQRTLREIQILLR 94
FDVG Y ++ IG GAYG+VSSA + +VAIKKI + F+ T +RTLRE++IL
Sbjct: 49 FDVGDEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKH 108
Query: 95 FRHENVIGIRDILRAST-LEAMRDVYIVQDLMETDLYKLLKSQQ-LSNDHICYFLYQILR 152
F+H+N+I I+DILR + + VY+V DLME+DL++++ S Q L+ +H+ YFLYQ+LR
Sbjct: 109 FKHDNIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLR 168
Query: 153 GLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLAR-IADPEHDHTGFLTEYVATRWYR 211
GLKY+HSA V+HRDLKPSNLL+N C+LKI DFG+AR + +H F+TEYVATRWYR
Sbjct: 169 GLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYR 228
Query: 212 APEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNC 271
APE+ML+ YT++ID+WSVGCI EML+ R +FPGK+Y+ QL I+ +LG+PS +
Sbjct: 229 APELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQA 288
Query: 272 IINMKARNYLQSLPSKTKVAWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEALAHPYLE 331
+ + R Y+QSLP + V W ++P +D +AL LL RML F P+ RI+ AL HP+L
Sbjct: 289 VGAERVRAYIQSLPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLA 348
Query: 332 QYYDPTDEVGQSP 344
+Y+DP DE +P
Sbjct: 349 KYHDPDDEPDCAP 361
>gi|20986512 mitogen-activated protein kinase 14 isoform 2 [Homo
sapiens]
Length = 360
Score = 308 bits (788), Expect = 6e-84
Identities = 157/311 (50%), Positives = 215/311 (69%), Gaps = 8/311 (2%)
Query: 36 FDVGPRYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKIS-PFEHQTYCQRTLREIQILLR 94
++V RY L +G GAYG V +A+D RVA+KK+S PF+ + +RT RE+++L
Sbjct: 18 WEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKH 77
Query: 95 FRHENVIGIRDILR-ASTLEAMRDVYIVQDLMETDLYKLLKSQQLSNDHICYFLYQILRG 153
+HENVIG+ D+ A +LE DVY+V LM DL ++K Q+L++DH+ + +YQILRG
Sbjct: 78 MKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRG 137
Query: 154 LKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAP 213
LKYIHSA+++HRDLKPSNL +N C+LKI DFGLAR D E +T YVATRWYRAP
Sbjct: 138 LKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDE------MTGYVATRWYRAP 191
Query: 214 EIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCII 273
EIMLN Y +++DIWSVGCI+AE+L+ R +FPG ++DQL IL ++G+P E L I
Sbjct: 192 EIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKIS 251
Query: 274 NMKARNYLQSLPSKTKVAWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEALAHPYLEQY 333
+ ARNY+QSL K+ +A +F ++ A+DLL++ML + +KRIT +ALAH Y QY
Sbjct: 252 SESARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQY 311
Query: 334 YDPTDEVGQSP 344
+DP DE P
Sbjct: 312 HDPDDEPVADP 322
>gi|4503069 mitogen-activated protein kinase 14 isoform 1 [Homo
sapiens]
Length = 360
Score = 303 bits (775), Expect = 2e-82
Identities = 153/311 (49%), Positives = 215/311 (69%), Gaps = 8/311 (2%)
Query: 36 FDVGPRYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKIS-PFEHQTYCQRTLREIQILLR 94
++V RY L +G GAYG V +A+D RVA+KK+S PF+ + +RT RE+++L
Sbjct: 18 WEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKH 77
Query: 95 FRHENVIGIRDILR-ASTLEAMRDVYIVQDLMETDLYKLLKSQQLSNDHICYFLYQILRG 153
+HENVIG+ D+ A +LE DVY+V LM DL ++K Q+L++DH+ + +YQILRG
Sbjct: 78 MKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRG 137
Query: 154 LKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAP 213
LKYIHSA+++HRDLKPSNL +N C+LKI DFGLAR D E +T YVATRWYRAP
Sbjct: 138 LKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDE------MTGYVATRWYRAP 191
Query: 214 EIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCII 273
EIMLN Y +++DIWSVGCI+AE+L+ R +FPG +++QL I+ + G+P +N +
Sbjct: 192 EIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTGTPPAYLINRMP 251
Query: 274 NMKARNYLQSLPSKTKVAWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEALAHPYLEQY 333
+ +ARNY+QSL K+ +A +F ++ A+DLL++ML + +KRIT +ALAH Y QY
Sbjct: 252 SHEARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQY 311
Query: 334 YDPTDEVGQSP 344
+DP DE P
Sbjct: 312 HDPDDEPVADP 322
>gi|20128774 mitogen-activated protein kinase 11 [Homo sapiens]
Length = 364
Score = 299 bits (765), Expect = 3e-81
Identities = 152/321 (47%), Positives = 217/321 (67%), Gaps = 8/321 (2%)
Query: 36 FDVGPRYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKIS-PFEHQTYCQRTLREIQILLR 94
++V R L+ +G GAYG V SAYD + +VA+KK+S PF+ + +RT RE+++L
Sbjct: 18 WEVPQRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQSLIHARRTYRELRLLKH 77
Query: 95 FRHENVIGIRDILR-ASTLEAMRDVYIVQDLMETDLYKLLKSQQLSNDHICYFLYQILRG 153
+HENVIG+ D+ A+++E +VY+V LM DL ++K Q LS++H+ + +YQ+LRG
Sbjct: 78 LKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQALSDEHVQFLVYQLLRG 137
Query: 154 LKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAP 213
LKYIHSA ++HRDLKPSN+ +N C+L+I DFGLAR AD E +T YVATRWYRAP
Sbjct: 138 LKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEE------MTGYVATRWYRAP 191
Query: 214 EIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCII 273
EIMLN Y +++DIWSVGCI+AE+L + +FPG Y+DQL I+ ++G+PS E L I
Sbjct: 192 EIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVGTPSPEVLAKIS 251
Query: 274 NMKARNYLQSLPSKTKVAWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEALAHPYLEQY 333
+ AR Y+QSLP + + +F ++ A+DLL RML + ++R++ EALAH Y QY
Sbjct: 252 SEHARTYIQSLPPMPQKDLSSIFRGANPLAIDLLGRMLVLDSDQRVSAAEALAHAYFSQY 311
Query: 334 YDPTDEVGQSPAAVGLGAGEQ 354
+DP DE P + A E+
Sbjct: 312 HDPEDEPEAEPYDESVEAKER 332
>gi|4506085 mitogen-activated protein kinase 13 [Homo sapiens]
Length = 365
Score = 279 bits (714), Expect = 2e-75
Identities = 141/300 (47%), Positives = 200/300 (66%), Gaps = 9/300 (3%)
Query: 42 YTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKIS-PFEHQTYCQRTLREIQILLRFRHENV 100
Y ++G GAYG V SA D +VAIKK+S PF+ + + +R RE+ +L +HENV
Sbjct: 25 YVSPTHVGSGAYGSVCSAIDKRSGEKVAIKKLSRPFQSEIFAKRAYRELLLLKHMQHENV 84
Query: 101 IGIRDILR-ASTLEAMRDVYIVQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHS 159
IG+ D+ AS+L D Y+V M+TDL K++ + S + I Y +YQ+L+GLKYIHS
Sbjct: 85 IGLLDVFTPASSLRNFYDFYLVMPFMQTDLQKIM-GMEFSEEKIQYLVYQMLKGLKYIHS 143
Query: 160 ANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNS 219
A V+HRDLKP NL +N C+LKI DFGLAR AD E +T YV TRWYRAPE++L+
Sbjct: 144 AGVVHRDLKPGNLAVNEDCELKILDFGLARHADAE------MTGYVVTRWYRAPEVILSW 197
Query: 220 KGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARN 279
Y +++DIWSVGCI+AEML+ + +F GK YLDQL IL + G P E + + + A++
Sbjct: 198 MHYNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTGVPGTEFVQKLNDKAAKS 257
Query: 280 YLQSLPSKTKVAWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDE 339
Y+QSLP + + +LFP++ +A DLL++ML + +KR+T +AL HP+ E + DP +E
Sbjct: 258 YIQSLPQTPRKDFTQLFPRASPQAADLLEKMLELDVDKRLTAAQALTHPFFEPFRDPEEE 317
>gi|48255970 mitogen-activated protein kinase 12 [Homo sapiens]
Length = 367
Score = 278 bits (711), Expect = 5e-75
Identities = 139/306 (45%), Positives = 201/306 (65%), Gaps = 8/306 (2%)
Query: 36 FDVGPRYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKI-SPFEHQTYCQRTLREIQILLR 94
++V Y LQ +G GAYG V SA D +VAIKK+ PF+ + + +R RE+++L
Sbjct: 21 WEVRAVYRDLQPVGSGAYGAVCSAVDGRTGAKVAIKKLYRPFQSELFAKRAYRELRLLKH 80
Query: 95 FRHENVIGIRDILRAS-TLEAMRDVYIVQDLMETDLYKLLKSQQLSNDHICYFLYQILRG 153
RHENVIG+ D+ TL+ D Y+V M TDL KL+K ++L D I + +YQ+L+G
Sbjct: 81 MRHENVIGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLMKHEKLGEDRIQFLVYQMLKG 140
Query: 154 LKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAP 213
L+YIH+A ++HRDLKP NL +N C+LKI DFGLAR AD E +T YV TRWYRAP
Sbjct: 141 LRYIHAAGIIHRDLKPGNLAVNEDCELKILDFGLARQADSE------MTGYVVTRWYRAP 194
Query: 214 EIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCII 273
E++LN YT+++DIWSVGCI+AEM++ + +F G +LDQL I+ + G+P E + +
Sbjct: 195 EVILNWMRYTQTVDIWSVGCIMAEMITGKTLFKGSDHLDQLKEIMKVTGTPPAEFVQRLQ 254
Query: 274 NMKARNYLQSLPSKTKVAWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEALAHPYLEQY 333
+ +A+NY++ LP K +A + + A++LL++ML + +R+T EALAHPY E
Sbjct: 255 SDEAKNYMKGLPELEKKDFASILTNASPLAVNLLEKMLVLDAEQRVTAGEALAHPYFESL 314
Query: 334 YDPTDE 339
+D DE
Sbjct: 315 HDTEDE 320
>gi|20986514 mitogen-activated protein kinase 14 isoform 3 [Homo
sapiens]
Length = 297
Score = 265 bits (678), Expect = 4e-71
Identities = 135/263 (51%), Positives = 184/263 (69%), Gaps = 8/263 (3%)
Query: 36 FDVGPRYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKIS-PFEHQTYCQRTLREIQILLR 94
++V RY L +G GAYG V +A+D RVA+KK+S PF+ + +RT RE+++L
Sbjct: 18 WEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKH 77
Query: 95 FRHENVIGIRDILR-ASTLEAMRDVYIVQDLMETDLYKLLKSQQLSNDHICYFLYQILRG 153
+HENVIG+ D+ A +LE DVY+V LM DL ++K Q+L++DH+ + +YQILRG
Sbjct: 78 MKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRG 137
Query: 154 LKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAP 213
LKYIHSA+++HRDLKPSNL +N C+LKI DFGLAR D E +T YVATRWYRAP
Sbjct: 138 LKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDE------MTGYVATRWYRAP 191
Query: 214 EIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCII 273
EIMLN Y +++DIWSVGCI+AE+L+ R +FPG ++DQL IL ++G+P E L I
Sbjct: 192 EIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKIS 251
Query: 274 NMKARNYLQSLPSKTKVAWAKLF 296
+ ARNY+QSL K+ +A +F
Sbjct: 252 SESARNYIQSLTQMPKMNFANVF 274
>gi|21237745 mitogen-activated protein kinase 9 isoform JNK2 beta2
[Homo sapiens]
Length = 424
Score = 258 bits (659), Expect = 6e-69
Identities = 137/328 (41%), Positives = 210/328 (64%), Gaps = 21/328 (6%)
Query: 31 VKGQPFDVGPRYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKIS-PFEHQTYCQRTLREI 89
V F V RY QL+ IG GA G+V +A+D V VA+KK+S PF++QT+ +R RE+
Sbjct: 15 VADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKRAYREL 74
Query: 90 QILLRFRHENVIGIRDILRAS-TLEAMRDVYIVQDLMETDLYKLLKSQQLSNDHICYFLY 148
+L H+N+I + ++ TLE +DVY+V +LM+ +L +++ +L ++ + Y LY
Sbjct: 75 VLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH-MELDHERMSYLLY 133
Query: 149 QILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATR 208
Q+L G+K++HSA ++HRDLKPSN+++ + C LKI DFGLAR A +T YV TR
Sbjct: 134 QMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF----MMTPYVVTR 189
Query: 209 WYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQED 268
+YRAPE++L GY +++DIWSVGCI+AEM+ ++ +FPG+ Y+DQ N ++ LG+PS E
Sbjct: 190 YYRAPEVIL-GMGYKENVDIWSVGCIMAEMVLHKVLFPGRDYIDQWNKVIEQLGTPSAEF 248
Query: 269 LNCIINMKARNYLQSLPSKTKVAWAKLFPK------------SDSKALDLLDRMLTFNPN 316
+ + RNY+++ P + + +LFP S+A DLL +ML +P+
Sbjct: 249 MK-KLQPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSKMLVIDPD 307
Query: 317 KRITVEEALAHPYLEQYYDPTDEVGQSP 344
KRI+V+EAL HPY+ +YDP + P
Sbjct: 308 KRISVDEALRHPYITVWYDPAEAEAPPP 335
>gi|21237742 mitogen-activated protein kinase 9 isoform JNK2 beta1
[Homo sapiens]
Length = 382
Score = 258 bits (659), Expect = 6e-69
Identities = 137/328 (41%), Positives = 210/328 (64%), Gaps = 21/328 (6%)
Query: 31 VKGQPFDVGPRYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKIS-PFEHQTYCQRTLREI 89
V F V RY QL+ IG GA G+V +A+D V VA+KK+S PF++QT+ +R RE+
Sbjct: 15 VADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKRAYREL 74
Query: 90 QILLRFRHENVIGIRDILRAS-TLEAMRDVYIVQDLMETDLYKLLKSQQLSNDHICYFLY 148
+L H+N+I + ++ TLE +DVY+V +LM+ +L +++ +L ++ + Y LY
Sbjct: 75 VLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH-MELDHERMSYLLY 133
Query: 149 QILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATR 208
Q+L G+K++HSA ++HRDLKPSN+++ + C LKI DFGLAR A +T YV TR
Sbjct: 134 QMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF----MMTPYVVTR 189
Query: 209 WYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQED 268
+YRAPE++L GY +++DIWSVGCI+AEM+ ++ +FPG+ Y+DQ N ++ LG+PS E
Sbjct: 190 YYRAPEVIL-GMGYKENVDIWSVGCIMAEMVLHKVLFPGRDYIDQWNKVIEQLGTPSAEF 248
Query: 269 LNCIINMKARNYLQSLPSKTKVAWAKLFPK------------SDSKALDLLDRMLTFNPN 316
+ + RNY+++ P + + +LFP S+A DLL +ML +P+
Sbjct: 249 MK-KLQPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSKMLVIDPD 307
Query: 317 KRITVEEALAHPYLEQYYDPTDEVGQSP 344
KRI+V+EAL HPY+ +YDP + P
Sbjct: 308 KRISVDEALRHPYITVWYDPAEAEAPPP 335
>gi|4506081 mitogen-activated protein kinase 10 isoform 1 [Homo
sapiens]
Length = 422
Score = 256 bits (653), Expect = 3e-68
Identities = 135/323 (41%), Positives = 207/323 (64%), Gaps = 21/323 (6%)
Query: 36 FDVGPRYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKIS-PFEHQTYCQRTLREIQILLR 94
F V RY L+ IG GA G+V +AYD V VAIKK+S PF++QT+ +R RE+ ++
Sbjct: 58 FTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKC 117
Query: 95 FRHENVIGIRDILRAS-TLEAMRDVYIVQDLMETDLYKLLKSQQLSNDHICYFLYQILRG 153
H+N+I + ++ TLE +DVY+V +LM+ +L ++++ +L ++ + Y LYQ+L G
Sbjct: 118 VNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQ-MELDHERMSYLLYQMLCG 176
Query: 154 LKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAP 213
+K++HSA ++HRDLKPSN+++ + C LKI DFGLAR A +T YV TR+YRAP
Sbjct: 177 IKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF----MMTPYVVTRYYRAP 232
Query: 214 EIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCII 273
E++L GY +++DIWSVGCI+ EM+ ++ +FPG+ Y+DQ N ++ LG+P E + +
Sbjct: 233 EVIL-GMGYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMK-KL 290
Query: 274 NMKARNYLQSLPSKTKVAWAKLFPKS------------DSKALDLLDRMLTFNPNKRITV 321
RNY+++ P + + KLFP S S+A DLL +ML +P KRI+V
Sbjct: 291 QPTVRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISV 350
Query: 322 EEALAHPYLEQYYDPTDEVGQSP 344
++AL HPY+ +YDP + P
Sbjct: 351 DDALQHPYINVWYDPAEVEAPPP 373
>gi|20986510 mitogen-activated protein kinase 10 isoform 2 [Homo
sapiens]
Length = 464
Score = 256 bits (653), Expect = 3e-68
Identities = 135/323 (41%), Positives = 207/323 (64%), Gaps = 21/323 (6%)
Query: 36 FDVGPRYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKIS-PFEHQTYCQRTLREIQILLR 94
F V RY L+ IG GA G+V +AYD V VAIKK+S PF++QT+ +R RE+ ++
Sbjct: 58 FTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKC 117
Query: 95 FRHENVIGIRDILRAS-TLEAMRDVYIVQDLMETDLYKLLKSQQLSNDHICYFLYQILRG 153
H+N+I + ++ TLE +DVY+V +LM+ +L ++++ +L ++ + Y LYQ+L G
Sbjct: 118 VNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQ-MELDHERMSYLLYQMLCG 176
Query: 154 LKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAP 213
+K++HSA ++HRDLKPSN+++ + C LKI DFGLAR A +T YV TR+YRAP
Sbjct: 177 IKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF----MMTPYVVTRYYRAP 232
Query: 214 EIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCII 273
E++L GY +++DIWSVGCI+ EM+ ++ +FPG+ Y+DQ N ++ LG+P E + +
Sbjct: 233 EVIL-GMGYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMK-KL 290
Query: 274 NMKARNYLQSLPSKTKVAWAKLFPKS------------DSKALDLLDRMLTFNPNKRITV 321
RNY+++ P + + KLFP S S+A DLL +ML +P KRI+V
Sbjct: 291 QPTVRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISV 350
Query: 322 EEALAHPYLEQYYDPTDEVGQSP 344
++AL HPY+ +YDP + P
Sbjct: 351 DDALQHPYINVWYDPAEVEAPPP 373
>gi|20986506 mitogen-activated protein kinase 10 isoform 3 [Homo
sapiens]
Length = 426
Score = 256 bits (653), Expect = 3e-68
Identities = 135/323 (41%), Positives = 207/323 (64%), Gaps = 21/323 (6%)
Query: 36 FDVGPRYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKIS-PFEHQTYCQRTLREIQILLR 94
F V RY L+ IG GA G+V +AYD V VAIKK+S PF++QT+ +R RE+ ++
Sbjct: 20 FTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKC 79
Query: 95 FRHENVIGIRDILRAS-TLEAMRDVYIVQDLMETDLYKLLKSQQLSNDHICYFLYQILRG 153
H+N+I + ++ TLE +DVY+V +LM+ +L ++++ +L ++ + Y LYQ+L G
Sbjct: 80 VNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQ-MELDHERMSYLLYQMLCG 138
Query: 154 LKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAP 213
+K++HSA ++HRDLKPSN+++ + C LKI DFGLAR A +T YV TR+YRAP
Sbjct: 139 IKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF----MMTPYVVTRYYRAP 194
Query: 214 EIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCII 273
E++L GY +++DIWSVGCI+ EM+ ++ +FPG+ Y+DQ N ++ LG+P E + +
Sbjct: 195 EVIL-GMGYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMK-KL 252
Query: 274 NMKARNYLQSLPSKTKVAWAKLFPKS------------DSKALDLLDRMLTFNPNKRITV 321
RNY+++ P + + KLFP S S+A DLL +ML +P KRI+V
Sbjct: 253 QPTVRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISV 312
Query: 322 EEALAHPYLEQYYDPTDEVGQSP 344
++AL HPY+ +YDP + P
Sbjct: 313 DDALQHPYINVWYDPAEVEAPPP 335
>gi|4506091 mitogen-activated protein kinase 6 [Homo sapiens]
Length = 721
Score = 255 bits (652), Expect = 4e-68
Identities = 141/314 (44%), Positives = 201/314 (64%), Gaps = 12/314 (3%)
Query: 36 FDVGPRYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRF 95
FD+G RY L+ +G G G+V SA D+ RVAIKKI + Q+ + LREI+I+ R
Sbjct: 14 FDLGSRYMDLKPLGCGGNGLVFSAVDNDCDKRVAIKKIVLTDPQSV-KHALREIKIIRRL 72
Query: 96 RHENVIGIRDILRAS---------TLEAMRDVYIVQDLMETDLYKLLKSQQLSNDHICYF 146
H+N++ + +IL S +L + VYIVQ+ METDL +L+ L +H F
Sbjct: 73 DHDNIVKVFEILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVLEQGPLLEEHARLF 132
Query: 147 LYQILRGLKYIHSANVLHRDLKPSNLLINTT-CDLKICDFGLARIADPEHDHTGFLTEYV 205
+YQ+LRGLKYIHSANVLHRDLKP+NL INT LKI DFGLARI DP + H G L+E +
Sbjct: 133 MYQLLRGLKYIHSANVLHRDLKPANLFINTEDLVLKIGDFGLARIMDPHYSHKGHLSEGL 192
Query: 206 ATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPS 265
T+WYR+P ++L+ YTK+ID+W+ GCI AEML+ + +F G H L+Q+ IL +
Sbjct: 193 VTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLTGKTLFAGAHELEQMQLILESIPVVH 252
Query: 266 QEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEAL 325
+ED ++++ Y+++ ++ +L P +ALD L+++LTF+P R+T EEAL
Sbjct: 253 EEDRQELLSV-IPVYIRNDMTEPHKPLTQLLPGISREALDFLEQILTFSPMDRLTAEEAL 311
Query: 326 AHPYLEQYYDPTDE 339
+HPY+ Y P DE
Sbjct: 312 SHPYMSIYSFPMDE 325
>gi|20986523 mitogen-activated protein kinase 8 isoform JNK1 alpha2
[Homo sapiens]
Length = 427
Score = 253 bits (645), Expect = 2e-67
Identities = 132/323 (40%), Positives = 208/323 (64%), Gaps = 21/323 (6%)
Query: 36 FDVGPRYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKIS-PFEHQTYCQRTLREIQILLR 94
F V RY L+ IG GA G+V +AYD + + VAIKK+S PF++QT+ +R RE+ ++
Sbjct: 20 FTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKC 79
Query: 95 FRHENVIGIRDILRAS-TLEAMRDVYIVQDLMETDLYKLLKSQQLSNDHICYFLYQILRG 153
H+N+IG+ ++ +LE +DVYIV +LM+ +L ++++ +L ++ + Y LYQ+L G
Sbjct: 80 VNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ-MELDHERMSYLLYQMLCG 138
Query: 154 LKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAP 213
+K++HSA ++HRDLKPSN+++ + C LKI DFGLAR A +T YV TR+YRAP
Sbjct: 139 IKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF----MMTPYVVTRYYRAP 194
Query: 214 EIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCII 273
E++L GY +++D+WSVGCI+ EM+ ++ +FPG+ Y+DQ N ++ LG+P E + +
Sbjct: 195 EVIL-GMGYKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQLGTPCPEFMK-KL 252
Query: 274 NMKARNYLQSLPSKTKVAWAKLFPK------------SDSKALDLLDRMLTFNPNKRITV 321
R Y+++ P ++ KLFP S+A DLL +ML + +KRI+V
Sbjct: 253 QPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSKMLVIDASKRISV 312
Query: 322 EEALAHPYLEQYYDPTDEVGQSP 344
+EAL HPY+ +YDP++ P
Sbjct: 313 DEALQHPYINVWYDPSEAEAPPP 335
>gi|4506095 mitogen-activated protein kinase 8 isoform JNK1 alpha1
[Homo sapiens]
Length = 384
Score = 253 bits (645), Expect = 2e-67
Identities = 132/323 (40%), Positives = 208/323 (64%), Gaps = 21/323 (6%)
Query: 36 FDVGPRYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKIS-PFEHQTYCQRTLREIQILLR 94
F V RY L+ IG GA G+V +AYD + + VAIKK+S PF++QT+ +R RE+ ++
Sbjct: 20 FTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKC 79
Query: 95 FRHENVIGIRDILRAS-TLEAMRDVYIVQDLMETDLYKLLKSQQLSNDHICYFLYQILRG 153
H+N+IG+ ++ +LE +DVYIV +LM+ +L ++++ +L ++ + Y LYQ+L G
Sbjct: 80 VNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ-MELDHERMSYLLYQMLCG 138
Query: 154 LKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAP 213
+K++HSA ++HRDLKPSN+++ + C LKI DFGLAR A +T YV TR+YRAP
Sbjct: 139 IKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF----MMTPYVVTRYYRAP 194
Query: 214 EIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCII 273
E++L GY +++D+WSVGCI+ EM+ ++ +FPG+ Y+DQ N ++ LG+P E + +
Sbjct: 195 EVIL-GMGYKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQLGTPCPEFMK-KL 252
Query: 274 NMKARNYLQSLPSKTKVAWAKLFPK------------SDSKALDLLDRMLTFNPNKRITV 321
R Y+++ P ++ KLFP S+A DLL +ML + +KRI+V
Sbjct: 253 QPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSKMLVIDASKRISV 312
Query: 322 EEALAHPYLEQYYDPTDEVGQSP 344
+EAL HPY+ +YDP++ P
Sbjct: 313 DEALQHPYINVWYDPSEAEAPPP 335
>gi|89276769 mitogen-activated protein kinase 4 [Homo sapiens]
Length = 587
Score = 250 bits (639), Expect = 1e-66
Identities = 135/317 (42%), Positives = 198/317 (62%), Gaps = 22/317 (6%)
Query: 36 FDVGPRYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRF 95
+D+G R+ Q +G G G+V SA D +VA+KKI+ + ++ + LREI+I+ R
Sbjct: 14 YDLGGRFVDFQPLGFGVNGLVLSAVDSRACRKVAVKKIALSDARSM-KHALREIKIIRRL 72
Query: 96 RHENVIGIRDILRASTLEAMRDV------YIVQDLMETDLYKLLKSQQLSNDHICYFLYQ 149
H+N++ + ++L + ++ YIVQ+ METDL +LL+ L+ +H F+YQ
Sbjct: 73 DHDNIVKVYEVLGPKGTDLQGELFKFSVAYIVQEYMETDLARLLEQGTLAEEHAKLFMYQ 132
Query: 150 ILRGLKYIHSANVLHRDLKPSNLLINTT-CDLKICDFGLARIADPEHDHTGFLTEYVATR 208
+LRGLKYIHSANVLHRDLKP+N+ I+T LKI DFGLARI D + H G+L+E + T+
Sbjct: 133 LLRGLKYIHSANVLHRDLKPANIFISTEDLVLKIGDFGLARIVDQHYSHKGYLSEGLVTK 192
Query: 209 WYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQED 268
WYR+P ++L+ YTK+ID+W+ GCILAEML+ R +F G H L+Q+ IL + +ED
Sbjct: 193 WYRSPRLLLSPNNYTKAIDMWAAGCILAEMLTGRMLFAGAHELEQMQLILETIPVIREED 252
Query: 269 LNCIINMKARNYLQSLPSKTKVAW------AKLFPKSDSKALDLLDRMLTFNPNKRITVE 322
+ L+ +PS W KL P+ +S+A+D L+++LTFNP R+T E
Sbjct: 253 KD--------ELLRVMPSFVSSTWEVKRPLRKLLPEVNSEAIDFLEKILTFNPMDRLTAE 304
Query: 323 EALAHPYLEQYYDPTDE 339
L HPY+ Y P DE
Sbjct: 305 MGLQHPYMSPYSCPEDE 321
>gi|20986521 mitogen-activated protein kinase 8 isoform JNK1 beta2
[Homo sapiens]
Length = 427
Score = 249 bits (637), Expect = 2e-66
Identities = 132/323 (40%), Positives = 205/323 (63%), Gaps = 21/323 (6%)
Query: 36 FDVGPRYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKIS-PFEHQTYCQRTLREIQILLR 94
F V RY L+ IG GA G+V +AYD + + VAIKK+S PF++QT+ +R RE+ ++
Sbjct: 20 FTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKC 79
Query: 95 FRHENVIGIRDILRAS-TLEAMRDVYIVQDLMETDLYKLLKSQQLSNDHICYFLYQILRG 153
H+N+IG+ ++ +LE +DVYIV +LM+ +L ++++ +L ++ + Y LYQ+L G
Sbjct: 80 VNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ-MELDHERMSYLLYQMLCG 138
Query: 154 LKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAP 213
+K++HSA ++HRDLKPSN+++ + C LKI DFGLAR A +T YV TR+YRAP
Sbjct: 139 IKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF----MMTPYVVTRYYRAP 194
Query: 214 EIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCII 273
E++L GY +++DIWSVGCI+ EM+ +FPG ++DQ N ++ LG+P E + +
Sbjct: 195 EVIL-GMGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQLGTPCPEFMK-KL 252
Query: 274 NMKARNYLQSLPSKTKVAWAKLFPK------------SDSKALDLLDRMLTFNPNKRITV 321
R Y+++ P ++ KLFP S+A DLL +ML + +KRI+V
Sbjct: 253 QPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSKMLVIDASKRISV 312
Query: 322 EEALAHPYLEQYYDPTDEVGQSP 344
+EAL HPY+ +YDP++ P
Sbjct: 313 DEALQHPYINVWYDPSEAEAPPP 335
>gi|20986519 mitogen-activated protein kinase 8 isoform JNK1 beta1
[Homo sapiens]
Length = 384
Score = 249 bits (637), Expect = 2e-66
Identities = 132/323 (40%), Positives = 205/323 (63%), Gaps = 21/323 (6%)
Query: 36 FDVGPRYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKIS-PFEHQTYCQRTLREIQILLR 94
F V RY L+ IG GA G+V +AYD + + VAIKK+S PF++QT+ +R RE+ ++
Sbjct: 20 FTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKC 79
Query: 95 FRHENVIGIRDILRAS-TLEAMRDVYIVQDLMETDLYKLLKSQQLSNDHICYFLYQILRG 153
H+N+IG+ ++ +LE +DVYIV +LM+ +L ++++ +L ++ + Y LYQ+L G
Sbjct: 80 VNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ-MELDHERMSYLLYQMLCG 138
Query: 154 LKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAP 213
+K++HSA ++HRDLKPSN+++ + C LKI DFGLAR A +T YV TR+YRAP
Sbjct: 139 IKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF----MMTPYVVTRYYRAP 194
Query: 214 EIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCII 273
E++L GY +++DIWSVGCI+ EM+ +FPG ++DQ N ++ LG+P E + +
Sbjct: 195 EVIL-GMGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQLGTPCPEFMK-KL 252
Query: 274 NMKARNYLQSLPSKTKVAWAKLFPK------------SDSKALDLLDRMLTFNPNKRITV 321
R Y+++ P ++ KLFP S+A DLL +ML + +KRI+V
Sbjct: 253 QPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSKMLVIDASKRISV 312
Query: 322 EEALAHPYLEQYYDPTDEVGQSP 344
+EAL HPY+ +YDP++ P
Sbjct: 313 DEALQHPYINVWYDPSEAEAPPP 335
>gi|21237739 mitogen-activated protein kinase 9 isoform JNK2 alpha1
[Homo sapiens]
Length = 382
Score = 248 bits (634), Expect = 5e-66
Identities = 134/328 (40%), Positives = 205/328 (62%), Gaps = 21/328 (6%)
Query: 31 VKGQPFDVGPRYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKIS-PFEHQTYCQRTLREI 89
V F V RY QL+ IG GA G+V +A+D V VA+KK+S PF++QT+ +R RE+
Sbjct: 15 VADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKRAYREL 74
Query: 90 QILLRFRHENVIGIRDILRAS-TLEAMRDVYIVQDLMETDLYKLLKSQQLSNDHICYFLY 148
+L H+N+I + ++ TLE +DVY+V +LM+ +L +++ +L ++ + Y LY
Sbjct: 75 VLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH-MELDHERMSYLLY 133
Query: 149 QILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATR 208
Q+L G+K++HSA ++HRDLKPSN+++ + C LKI DFGLAR A +T YV TR
Sbjct: 134 QMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF----MMTPYVVTR 189
Query: 209 WYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQED 268
+YRAPE++L GY +++DIWSVGCI+ E++ IF G ++DQ N ++ LG+PS E
Sbjct: 190 YYRAPEVIL-GMGYKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQLGTPSAEF 248
Query: 269 LNCIINMKARNYLQSLPSKTKVAWAKLFPK------------SDSKALDLLDRMLTFNPN 316
+ + RNY+++ P + + +LFP S+A DLL +ML +P+
Sbjct: 249 MK-KLQPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSKMLVIDPD 307
Query: 317 KRITVEEALAHPYLEQYYDPTDEVGQSP 344
KRI+V+EAL HPY+ +YDP + P
Sbjct: 308 KRISVDEALRHPYITVWYDPAEAEAPPP 335
>gi|21237736 mitogen-activated protein kinase 9 isoform JNK2 alpha2
[Homo sapiens]
Length = 424
Score = 248 bits (634), Expect = 5e-66
Identities = 134/328 (40%), Positives = 205/328 (62%), Gaps = 21/328 (6%)
Query: 31 VKGQPFDVGPRYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKIS-PFEHQTYCQRTLREI 89
V F V RY QL+ IG GA G+V +A+D V VA+KK+S PF++QT+ +R RE+
Sbjct: 15 VADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKRAYREL 74
Query: 90 QILLRFRHENVIGIRDILRAS-TLEAMRDVYIVQDLMETDLYKLLKSQQLSNDHICYFLY 148
+L H+N+I + ++ TLE +DVY+V +LM+ +L +++ +L ++ + Y LY
Sbjct: 75 VLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH-MELDHERMSYLLY 133
Query: 149 QILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATR 208
Q+L G+K++HSA ++HRDLKPSN+++ + C LKI DFGLAR A +T YV TR
Sbjct: 134 QMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF----MMTPYVVTR 189
Query: 209 WYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQED 268
+YRAPE++L GY +++DIWSVGCI+ E++ IF G ++DQ N ++ LG+PS E
Sbjct: 190 YYRAPEVIL-GMGYKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQLGTPSAEF 248
Query: 269 LNCIINMKARNYLQSLPSKTKVAWAKLFPK------------SDSKALDLLDRMLTFNPN 316
+ + RNY+++ P + + +LFP S+A DLL +ML +P+
Sbjct: 249 MK-KLQPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSKMLVIDPD 307
Query: 317 KRITVEEALAHPYLEQYYDPTDEVGQSP 344
KRI+V+EAL HPY+ +YDP + P
Sbjct: 308 KRISVDEALRHPYITVWYDPAEAEAPPP 335
>gi|95147356 mitogen-activated protein kinase 15 [Homo sapiens]
Length = 544
Score = 248 bits (633), Expect = 6e-66
Identities = 138/305 (45%), Positives = 195/305 (63%), Gaps = 9/305 (2%)
Query: 41 RYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKI-SPFEHQTYCQRTLREIQILLRFR-HE 98
RY + +G+GAYG+V A D VAIKKI F +T QRT REI +L F H
Sbjct: 12 RYLLRRQLGQGAYGIVWKAVDRRTGEVVAIKKIFDAFRDKTDAQRTFREITLLQEFGDHP 71
Query: 99 NVIGIRDILRASTLEAMRDVYIVQDLMETDLYKLLKSQQLSND-HICYFLYQILRGLKYI 157
N+I + D++RA E RD+Y+V + M+TDL +++ L D H+ YQ+LR +++
Sbjct: 72 NIISLLDVIRA---ENDRDIYLVFEFMDTDLNAVIRKGGLLQDVHVRSIFYQLLRATRFL 128
Query: 158 HSANVLHRDLKPSNLLINTTCDLKICDFGLAR-IAD-PEHDHTGFLTEYVATRWYRAPEI 215
HS +V+HRD KPSN+L++ C +K+CDFGLAR + D PE +TEYVATRWYRAPE+
Sbjct: 129 HSGHVVHRDQKPSNVLLDANCTVKLCDFGLARSLGDLPEGPEDQAVTEYVATRWYRAPEV 188
Query: 216 MLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINM 275
+L+S YT +D+WS+GCIL EML RP+FPG L QL IL + PS+EDL + +
Sbjct: 189 LLSSHRYTLGVDMWSLGCILGEMLRGRPLFPGTSTLHQLELILETIPPPSEEDLLALGSG 248
Query: 276 KARNYLQSLPSKTKVAWAKLFPKSDS-KALDLLDRMLTFNPNKRITVEEALAHPYLEQYY 334
+ L L S+ + L P S +ALDLL R+L F P+KR++ +AL HPY+++++
Sbjct: 249 CRASVLHQLGSRPRQTLDALLPPDTSPEALDLLRRLLVFAPDKRLSATQALQHPYVQRFH 308
Query: 335 DPTDE 339
P+DE
Sbjct: 309 CPSDE 313
>gi|20986516 mitogen-activated protein kinase 14 isoform 4 [Homo
sapiens]
Length = 307
Score = 247 bits (631), Expect = 1e-65
Identities = 125/239 (52%), Positives = 169/239 (70%), Gaps = 8/239 (3%)
Query: 36 FDVGPRYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKIS-PFEHQTYCQRTLREIQILLR 94
++V RY L +G GAYG V +A+D RVA+KK+S PF+ + +RT RE+++L
Sbjct: 18 WEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKH 77
Query: 95 FRHENVIGIRDILR-ASTLEAMRDVYIVQDLMETDLYKLLKSQQLSNDHICYFLYQILRG 153
+HENVIG+ D+ A +LE DVY+V LM DL ++K Q+L++DH+ + +YQILRG
Sbjct: 78 MKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRG 137
Query: 154 LKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAP 213
LKYIHSA+++HRDLKPSNL +N C+LKI DFGLAR D E +T YVATRWYRAP
Sbjct: 138 LKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDE------MTGYVATRWYRAP 191
Query: 214 EIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCI 272
EIMLN Y +++DIWSVGCI+AE+L+ R +FPG ++DQL IL ++G+P E L I
Sbjct: 192 EIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKI 250
>gi|149408126 nemo like kinase [Homo sapiens]
Length = 527
Score = 247 bits (630), Expect = 1e-65
Identities = 129/288 (44%), Positives = 196/288 (68%), Gaps = 5/288 (1%)
Query: 48 IGEGAYGMVSSAYDHVRKTRVAIKKI-SPFEHQTYCQRTLREIQILLRFRHENVIGIRDI 106
IG GA+G+V S D RVA+KK+ + F++ C+R RE+++L F+H+NV+ DI
Sbjct: 144 IGYGAFGVVWSVTDPRDGKRVALKKMPNVFQNLVSCKRVFRELKMLCFFKHDNVLSALDI 203
Query: 107 LRASTLEAMRDVYIVQDLMETDLYKLLKSQQ-LSNDHICYFLYQILRGLKYIHSANVLHR 165
L+ ++ ++Y+V +LM++DL+K++ S Q LS+DH+ FLYQILRGLKY+HSA +LHR
Sbjct: 204 LQPPHIDYFEEIYVVTELMQSDLHKIIVSPQPLSSDHVKVFLYQILRGLKYLHSAGILHR 263
Query: 166 DLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKS 225
D+KP NLL+N+ C LKICDFGLAR+ E D + +T+ V T++YRAPEI++ S+ Y+ +
Sbjct: 264 DIKPGNLLVNSNCVLKICDFGLARV--EELDESRHMTQEVVTQYYRAPEILMGSRHYSNA 321
Query: 226 IDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLP 285
IDIWSVGCI AE+L R +F + + QL+ I +LG+PS E + + L+
Sbjct: 322 IDIWSVGCIFAELLGRRILFQAQSPIQQLDLITDLLGTPSLEAMRTACEGAKAHILRGPH 381
Query: 286 SKTKV-AWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEALAHPYLEQ 332
+ + L ++ +A+ LL RML F+P+KRI+ ++ALAHPYL++
Sbjct: 382 KQPSLPVLYTLSSQATHEAVHLLCRMLVFDPSKRISAKDALAHPYLDE 429
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.138 0.414
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,101,843
Number of Sequences: 37866
Number of extensions: 646152
Number of successful extensions: 3943
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 722
Number of HSP's successfully gapped in prelim test: 82
Number of HSP's that attempted gapping in prelim test: 1827
Number of HSP's gapped (non-prelim): 1028
length of query: 357
length of database: 18,247,518
effective HSP length: 103
effective length of query: 254
effective length of database: 14,347,320
effective search space: 3644219280
effective search space used: 3644219280
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.