BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|91199540 dihydrolipoamide dehydrogenase precursor [Homo sapiens] (509 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|91199540 dihydrolipoamide dehydrogenase precursor [Homo sapiens] 1014 0.0 gi|33519426 thioredoxin reductase 1 isoform 2 [Homo sapiens] 191 1e-48 gi|148277071 thioredoxin reductase 1 isoform 3 [Homo sapiens] 191 1e-48 gi|148277065 thioredoxin reductase 1 isoform 1 [Homo sapiens] 191 1e-48 gi|33519430 thioredoxin reductase 1 isoform 2 [Homo sapiens] 191 1e-48 gi|33519428 thioredoxin reductase 1 isoform 2 [Homo sapiens] 191 1e-48 gi|50301238 glutathione reductase [Homo sapiens] 180 2e-45 gi|22035672 thioredoxin reductase 2 precursor [Homo sapiens] 179 4e-45 gi|226437568 apoptosis-inducing factor, mitochondrion-associated... 64 2e-10 gi|65787454 apoptosis-inducing factor, mitochondrion-associated,... 64 2e-10 gi|21389617 apoptosis-inducing factor, mitochondrion-associated,... 64 2e-10 gi|229577391 pyridine nucleotide-disulphide oxidoreductase domai... 37 0.043 gi|203098013 all-trans-13,14-dihydroretinol saturase [Homo sapiens] 37 0.056 gi|51036596 pyridine nucleotide-disulphide oxidoreductase domain... 36 0.073 gi|119703746 electron-transferring-flavoprotein dehydrogenase pr... 34 0.36 gi|62865635 squalene epoxidase [Homo sapiens] 33 0.80 gi|23821023 interleukin 4 induced 1 isoform 1 precursor [Homo sa... 32 1.4 gi|27477089 interleukin 4 induced 1 isoform 2 [Homo sapiens] 32 1.4 gi|58761544 amine oxidase (flavin containing) domain 2 isoform a... 32 1.4 gi|58761546 amine oxidase (flavin containing) domain 2 isoform b... 32 1.4 gi|38016947 complement component 5 preproprotein [Homo sapiens] 31 2.3 gi|116256451 amine oxidase (flavin containing) domain 1 [Homo sa... 31 2.3 gi|133908616 glycerol-3-phosphate dehydrogenase 2, mitochondrial... 30 4.0 gi|133908614 glycerol-3-phosphate dehydrogenase 2, mitochondrial... 30 4.0 gi|7662284 microtubule associated monoxygenase, calponin and LIM... 30 4.0 gi|156416003 succinate dehydrogenase complex, subunit A, flavopr... 30 5.2 gi|18105007 carbamoylphosphate synthetase 2/aspartate transcarba... 30 5.2 gi|11128041 protocadherin gamma subfamily A, 10 isoform 1 precur... 29 8.9 gi|14196448 protocadherin gamma subfamily A, 10 isoform 2 precur... 29 8.9 >gi|91199540 dihydrolipoamide dehydrogenase precursor [Homo sapiens] Length = 509 Score = 1014 bits (2623), Expect = 0.0 Identities = 509/509 (100%), Positives = 509/509 (100%) Query: 1 MQSWSRVYCSLAKRGHFNRISHGLQGLSAVPLRTYADQPIDADVTVIGSGPGGYVAAIKA 60 MQSWSRVYCSLAKRGHFNRISHGLQGLSAVPLRTYADQPIDADVTVIGSGPGGYVAAIKA Sbjct: 1 MQSWSRVYCSLAKRGHFNRISHGLQGLSAVPLRTYADQPIDADVTVIGSGPGGYVAAIKA 60 Query: 61 AQLGFKTVCIEKNETLGGTCLNVGCIPSKALLNNSHYYHMAHGKDFASRGIEMSEVRLNL 120 AQLGFKTVCIEKNETLGGTCLNVGCIPSKALLNNSHYYHMAHGKDFASRGIEMSEVRLNL Sbjct: 61 AQLGFKTVCIEKNETLGGTCLNVGCIPSKALLNNSHYYHMAHGKDFASRGIEMSEVRLNL 120 Query: 121 DKMMEQKSTAVKALTGGIAHLFKQNKVVHVNGYGKITGKNQVTATKADGGTQVIDTKNIL 180 DKMMEQKSTAVKALTGGIAHLFKQNKVVHVNGYGKITGKNQVTATKADGGTQVIDTKNIL Sbjct: 121 DKMMEQKSTAVKALTGGIAHLFKQNKVVHVNGYGKITGKNQVTATKADGGTQVIDTKNIL 180 Query: 181 IATGSEVTPFPGITIDEDTIVSSTGALSLKKVPEKMVVIGAGVIGVELGSVWQRLGADVT 240 IATGSEVTPFPGITIDEDTIVSSTGALSLKKVPEKMVVIGAGVIGVELGSVWQRLGADVT Sbjct: 181 IATGSEVTPFPGITIDEDTIVSSTGALSLKKVPEKMVVIGAGVIGVELGSVWQRLGADVT 240 Query: 241 AVEFLGHVGGVGIDMEISKNFQRILQKQGFKFKLNTKVTGATKKSDGKIDVSIEAASGGK 300 AVEFLGHVGGVGIDMEISKNFQRILQKQGFKFKLNTKVTGATKKSDGKIDVSIEAASGGK Sbjct: 241 AVEFLGHVGGVGIDMEISKNFQRILQKQGFKFKLNTKVTGATKKSDGKIDVSIEAASGGK 300 Query: 301 AEVITCDVLLVCIGRRPFTKNLGLEELGIELDPRGRIPVNTRFQTKIPNIYAIGDVVAGP 360 AEVITCDVLLVCIGRRPFTKNLGLEELGIELDPRGRIPVNTRFQTKIPNIYAIGDVVAGP Sbjct: 301 AEVITCDVLLVCIGRRPFTKNLGLEELGIELDPRGRIPVNTRFQTKIPNIYAIGDVVAGP 360 Query: 361 MLAHKAEDEGIICVEGMAGGAVHIDYNCVPSVIYTHPEVAWVGKSEEQLKEEGIEYKVGK 420 MLAHKAEDEGIICVEGMAGGAVHIDYNCVPSVIYTHPEVAWVGKSEEQLKEEGIEYKVGK Sbjct: 361 MLAHKAEDEGIICVEGMAGGAVHIDYNCVPSVIYTHPEVAWVGKSEEQLKEEGIEYKVGK 420 Query: 421 FPFAANSRAKTNADTDGMVKILGQKSTDRVLGAHILGPGAGEMVNEAALALEYGASCEDI 480 FPFAANSRAKTNADTDGMVKILGQKSTDRVLGAHILGPGAGEMVNEAALALEYGASCEDI Sbjct: 421 FPFAANSRAKTNADTDGMVKILGQKSTDRVLGAHILGPGAGEMVNEAALALEYGASCEDI 480 Query: 481 ARVCHAHPTLSEAFREANLAASFGKSINF 509 ARVCHAHPTLSEAFREANLAASFGKSINF Sbjct: 481 ARVCHAHPTLSEAFREANLAASFGKSINF 509 >gi|33519426 thioredoxin reductase 1 isoform 2 [Homo sapiens] Length = 499 Score = 191 bits (486), Expect = 1e-48 Identities = 146/487 (29%), Positives = 241/487 (49%), Gaps = 26/487 (5%) Query: 41 DADVTVIGSGPGGYVAAIKAAQLGFKTVCIE--------KNETLGGTCLNVGCIPSKALL 92 D D+ +IG G GG AA +AAQ G K + ++ LGGTC+NVGCIP K L+ Sbjct: 12 DYDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKK-LM 70 Query: 93 NNSHYYHMAHGKDFASRGIEMSE-VRLNLDKMMEQKSTAVKALTGGIAHLFKQNKVVHVN 151 + + A +D + G ++ E V+ + D+M+E + +L G ++ KVV+ N Sbjct: 71 HQAALLGQAL-QDSRNYGWKVEETVKHDWDRMIEAVQNHIGSLNWGYRVALREKKVVYEN 129 Query: 152 GYGKITGKNQVTATKADGGTQVIDTKNILIATGSEVTPFPGITIDEDTIVSSTGALSLKK 211 YG+ G +++ AT G ++ + LIATG E + GI D++ +SS SL Sbjct: 130 AYGQFIGPHRIKATNNKGKEKIYSAERFLIATG-ERPRYLGIPGDKEYCISSDDLFSLPY 188 Query: 212 VPEKMVVIGAGVIGVELGSVWQRLGADVTAVEFLGHVGGVGIDMEISKNFQRILQKQGFK 271 P K +V+GA + +E +G DVT + + + G D +++ +++ G K Sbjct: 189 CPGKTLVVGASYVALECAGFLAGIGLDVTVM--VRSILLRGFDQDMANKIGEHMEEHGIK 246 Query: 272 FK---LNTKVTGATKKSDGKIDVSIEAASGGKAEVITCDVLLVCIGRRPFTKNLGLEELG 328 F + KV + G++ V ++ + + + +++ IGR T+ +GLE +G Sbjct: 247 FIRQFVPIKVEQIEAGTPGRLRVVAQSTNSEEIIEGEYNTVMLAIGRDACTRKIGLETVG 306 Query: 329 IELDPR-GRIPVNTRFQTKIPNIYAIGDVVAGPM-LAHKAEDEGIICVEGM-AGGAVHID 385 ++++ + G+IPV QT +P IYAIGD++ + L A G + + + AG V D Sbjct: 307 VKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLYAGSTVKCD 366 Query: 386 YNCVPSVIYTHPEVAWVGKSEEQ----LKEEGIE-YKVGKFPFAANSRAKTNADTDGMVK 440 Y VP+ ++T E G SEE+ EE IE Y +P ++ N + Sbjct: 367 YENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKI- 425 Query: 441 ILGQKSTDRVLGAHILGPGAGEMVNEAALALEYGASCEDIARVCHAHPTLSEAFREANLA 500 I K +RV+G H+LGP AGE+ A AL+ G + + + HP +E F ++ Sbjct: 426 ICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVT 485 Query: 501 ASFGKSI 507 G SI Sbjct: 486 KRSGASI 492 >gi|148277071 thioredoxin reductase 1 isoform 3 [Homo sapiens] Length = 649 Score = 191 bits (486), Expect = 1e-48 Identities = 146/487 (29%), Positives = 241/487 (49%), Gaps = 26/487 (5%) Query: 41 DADVTVIGSGPGGYVAAIKAAQLGFKTVCIE--------KNETLGGTCLNVGCIPSKALL 92 D D+ +IG G GG AA +AAQ G K + ++ LGGTC+NVGCIP K L+ Sbjct: 162 DYDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKK-LM 220 Query: 93 NNSHYYHMAHGKDFASRGIEMSE-VRLNLDKMMEQKSTAVKALTGGIAHLFKQNKVVHVN 151 + + A +D + G ++ E V+ + D+M+E + +L G ++ KVV+ N Sbjct: 221 HQAALLGQAL-QDSRNYGWKVEETVKHDWDRMIEAVQNHIGSLNWGYRVALREKKVVYEN 279 Query: 152 GYGKITGKNQVTATKADGGTQVIDTKNILIATGSEVTPFPGITIDEDTIVSSTGALSLKK 211 YG+ G +++ AT G ++ + LIATG E + GI D++ +SS SL Sbjct: 280 AYGQFIGPHRIKATNNKGKEKIYSAERFLIATG-ERPRYLGIPGDKEYCISSDDLFSLPY 338 Query: 212 VPEKMVVIGAGVIGVELGSVWQRLGADVTAVEFLGHVGGVGIDMEISKNFQRILQKQGFK 271 P K +V+GA + +E +G DVT + + + G D +++ +++ G K Sbjct: 339 CPGKTLVVGASYVALECAGFLAGIGLDVTVM--VRSILLRGFDQDMANKIGEHMEEHGIK 396 Query: 272 FK---LNTKVTGATKKSDGKIDVSIEAASGGKAEVITCDVLLVCIGRRPFTKNLGLEELG 328 F + KV + G++ V ++ + + + +++ IGR T+ +GLE +G Sbjct: 397 FIRQFVPIKVEQIEAGTPGRLRVVAQSTNSEEIIEGEYNTVMLAIGRDACTRKIGLETVG 456 Query: 329 IELDPR-GRIPVNTRFQTKIPNIYAIGDVVAGPM-LAHKAEDEGIICVEGM-AGGAVHID 385 ++++ + G+IPV QT +P IYAIGD++ + L A G + + + AG V D Sbjct: 457 VKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLYAGSTVKCD 516 Query: 386 YNCVPSVIYTHPEVAWVGKSEEQ----LKEEGIE-YKVGKFPFAANSRAKTNADTDGMVK 440 Y VP+ ++T E G SEE+ EE IE Y +P ++ N + Sbjct: 517 YENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKI- 575 Query: 441 ILGQKSTDRVLGAHILGPGAGEMVNEAALALEYGASCEDIARVCHAHPTLSEAFREANLA 500 I K +RV+G H+LGP AGE+ A AL+ G + + + HP +E F ++ Sbjct: 576 ICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVT 635 Query: 501 ASFGKSI 507 G SI Sbjct: 636 KRSGASI 642 >gi|148277065 thioredoxin reductase 1 isoform 1 [Homo sapiens] Length = 551 Score = 191 bits (486), Expect = 1e-48 Identities = 146/487 (29%), Positives = 241/487 (49%), Gaps = 26/487 (5%) Query: 41 DADVTVIGSGPGGYVAAIKAAQLGFKTVCIE--------KNETLGGTCLNVGCIPSKALL 92 D D+ +IG G GG AA +AAQ G K + ++ LGGTC+NVGCIP K L+ Sbjct: 64 DYDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKK-LM 122 Query: 93 NNSHYYHMAHGKDFASRGIEMSE-VRLNLDKMMEQKSTAVKALTGGIAHLFKQNKVVHVN 151 + + A +D + G ++ E V+ + D+M+E + +L G ++ KVV+ N Sbjct: 123 HQAALLGQAL-QDSRNYGWKVEETVKHDWDRMIEAVQNHIGSLNWGYRVALREKKVVYEN 181 Query: 152 GYGKITGKNQVTATKADGGTQVIDTKNILIATGSEVTPFPGITIDEDTIVSSTGALSLKK 211 YG+ G +++ AT G ++ + LIATG E + GI D++ +SS SL Sbjct: 182 AYGQFIGPHRIKATNNKGKEKIYSAERFLIATG-ERPRYLGIPGDKEYCISSDDLFSLPY 240 Query: 212 VPEKMVVIGAGVIGVELGSVWQRLGADVTAVEFLGHVGGVGIDMEISKNFQRILQKQGFK 271 P K +V+GA + +E +G DVT + + + G D +++ +++ G K Sbjct: 241 CPGKTLVVGASYVALECAGFLAGIGLDVTVM--VRSILLRGFDQDMANKIGEHMEEHGIK 298 Query: 272 FK---LNTKVTGATKKSDGKIDVSIEAASGGKAEVITCDVLLVCIGRRPFTKNLGLEELG 328 F + KV + G++ V ++ + + + +++ IGR T+ +GLE +G Sbjct: 299 FIRQFVPIKVEQIEAGTPGRLRVVAQSTNSEEIIEGEYNTVMLAIGRDACTRKIGLETVG 358 Query: 329 IELDPR-GRIPVNTRFQTKIPNIYAIGDVVAGPM-LAHKAEDEGIICVEGM-AGGAVHID 385 ++++ + G+IPV QT +P IYAIGD++ + L A G + + + AG V D Sbjct: 359 VKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLYAGSTVKCD 418 Query: 386 YNCVPSVIYTHPEVAWVGKSEEQ----LKEEGIE-YKVGKFPFAANSRAKTNADTDGMVK 440 Y VP+ ++T E G SEE+ EE IE Y +P ++ N + Sbjct: 419 YENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKI- 477 Query: 441 ILGQKSTDRVLGAHILGPGAGEMVNEAALALEYGASCEDIARVCHAHPTLSEAFREANLA 500 I K +RV+G H+LGP AGE+ A AL+ G + + + HP +E F ++ Sbjct: 478 ICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVT 537 Query: 501 ASFGKSI 507 G SI Sbjct: 538 KRSGASI 544 >gi|33519430 thioredoxin reductase 1 isoform 2 [Homo sapiens] Length = 499 Score = 191 bits (486), Expect = 1e-48 Identities = 146/487 (29%), Positives = 241/487 (49%), Gaps = 26/487 (5%) Query: 41 DADVTVIGSGPGGYVAAIKAAQLGFKTVCIE--------KNETLGGTCLNVGCIPSKALL 92 D D+ +IG G GG AA +AAQ G K + ++ LGGTC+NVGCIP K L+ Sbjct: 12 DYDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKK-LM 70 Query: 93 NNSHYYHMAHGKDFASRGIEMSE-VRLNLDKMMEQKSTAVKALTGGIAHLFKQNKVVHVN 151 + + A +D + G ++ E V+ + D+M+E + +L G ++ KVV+ N Sbjct: 71 HQAALLGQAL-QDSRNYGWKVEETVKHDWDRMIEAVQNHIGSLNWGYRVALREKKVVYEN 129 Query: 152 GYGKITGKNQVTATKADGGTQVIDTKNILIATGSEVTPFPGITIDEDTIVSSTGALSLKK 211 YG+ G +++ AT G ++ + LIATG E + GI D++ +SS SL Sbjct: 130 AYGQFIGPHRIKATNNKGKEKIYSAERFLIATG-ERPRYLGIPGDKEYCISSDDLFSLPY 188 Query: 212 VPEKMVVIGAGVIGVELGSVWQRLGADVTAVEFLGHVGGVGIDMEISKNFQRILQKQGFK 271 P K +V+GA + +E +G DVT + + + G D +++ +++ G K Sbjct: 189 CPGKTLVVGASYVALECAGFLAGIGLDVTVM--VRSILLRGFDQDMANKIGEHMEEHGIK 246 Query: 272 FK---LNTKVTGATKKSDGKIDVSIEAASGGKAEVITCDVLLVCIGRRPFTKNLGLEELG 328 F + KV + G++ V ++ + + + +++ IGR T+ +GLE +G Sbjct: 247 FIRQFVPIKVEQIEAGTPGRLRVVAQSTNSEEIIEGEYNTVMLAIGRDACTRKIGLETVG 306 Query: 329 IELDPR-GRIPVNTRFQTKIPNIYAIGDVVAGPM-LAHKAEDEGIICVEGM-AGGAVHID 385 ++++ + G+IPV QT +P IYAIGD++ + L A G + + + AG V D Sbjct: 307 VKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLYAGSTVKCD 366 Query: 386 YNCVPSVIYTHPEVAWVGKSEEQ----LKEEGIE-YKVGKFPFAANSRAKTNADTDGMVK 440 Y VP+ ++T E G SEE+ EE IE Y +P ++ N + Sbjct: 367 YENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKI- 425 Query: 441 ILGQKSTDRVLGAHILGPGAGEMVNEAALALEYGASCEDIARVCHAHPTLSEAFREANLA 500 I K +RV+G H+LGP AGE+ A AL+ G + + + HP +E F ++ Sbjct: 426 ICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVT 485 Query: 501 ASFGKSI 507 G SI Sbjct: 486 KRSGASI 492 >gi|33519428 thioredoxin reductase 1 isoform 2 [Homo sapiens] Length = 499 Score = 191 bits (486), Expect = 1e-48 Identities = 146/487 (29%), Positives = 241/487 (49%), Gaps = 26/487 (5%) Query: 41 DADVTVIGSGPGGYVAAIKAAQLGFKTVCIE--------KNETLGGTCLNVGCIPSKALL 92 D D+ +IG G GG AA +AAQ G K + ++ LGGTC+NVGCIP K L+ Sbjct: 12 DYDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKK-LM 70 Query: 93 NNSHYYHMAHGKDFASRGIEMSE-VRLNLDKMMEQKSTAVKALTGGIAHLFKQNKVVHVN 151 + + A +D + G ++ E V+ + D+M+E + +L G ++ KVV+ N Sbjct: 71 HQAALLGQAL-QDSRNYGWKVEETVKHDWDRMIEAVQNHIGSLNWGYRVALREKKVVYEN 129 Query: 152 GYGKITGKNQVTATKADGGTQVIDTKNILIATGSEVTPFPGITIDEDTIVSSTGALSLKK 211 YG+ G +++ AT G ++ + LIATG E + GI D++ +SS SL Sbjct: 130 AYGQFIGPHRIKATNNKGKEKIYSAERFLIATG-ERPRYLGIPGDKEYCISSDDLFSLPY 188 Query: 212 VPEKMVVIGAGVIGVELGSVWQRLGADVTAVEFLGHVGGVGIDMEISKNFQRILQKQGFK 271 P K +V+GA + +E +G DVT + + + G D +++ +++ G K Sbjct: 189 CPGKTLVVGASYVALECAGFLAGIGLDVTVM--VRSILLRGFDQDMANKIGEHMEEHGIK 246 Query: 272 FK---LNTKVTGATKKSDGKIDVSIEAASGGKAEVITCDVLLVCIGRRPFTKNLGLEELG 328 F + KV + G++ V ++ + + + +++ IGR T+ +GLE +G Sbjct: 247 FIRQFVPIKVEQIEAGTPGRLRVVAQSTNSEEIIEGEYNTVMLAIGRDACTRKIGLETVG 306 Query: 329 IELDPR-GRIPVNTRFQTKIPNIYAIGDVVAGPM-LAHKAEDEGIICVEGM-AGGAVHID 385 ++++ + G+IPV QT +P IYAIGD++ + L A G + + + AG V D Sbjct: 307 VKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLYAGSTVKCD 366 Query: 386 YNCVPSVIYTHPEVAWVGKSEEQ----LKEEGIE-YKVGKFPFAANSRAKTNADTDGMVK 440 Y VP+ ++T E G SEE+ EE IE Y +P ++ N + Sbjct: 367 YENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKI- 425 Query: 441 ILGQKSTDRVLGAHILGPGAGEMVNEAALALEYGASCEDIARVCHAHPTLSEAFREANLA 500 I K +RV+G H+LGP AGE+ A AL+ G + + + HP +E F ++ Sbjct: 426 ICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVT 485 Query: 501 ASFGKSI 507 G SI Sbjct: 486 KRSGASI 492 >gi|50301238 glutathione reductase [Homo sapiens] Length = 522 Score = 180 bits (457), Expect = 2e-45 Identities = 143/477 (29%), Positives = 227/477 (47%), Gaps = 53/477 (11%) Query: 43 DVTVIGSGPGGYVAAIKAAQLGFKTVCIEKNETLGGTCLNVGCIPSKALLNNSHYYHMAH 102 D VIG G GG +A +AA+LG + +E ++ LGGTC+NVGC+P K + N + + H Sbjct: 66 DYLVIGGGSGGLASARRAAELGARAAVVESHK-LGGTCVNVGCVPKKVMWNTAVHSEFMH 124 Query: 103 GKDFASRGIEMSEVRLNLDKMMEQKSTAVKALTGGIAHLFKQNKVVHVNGYGKITGKNQV 162 D A G E + N + E++ V L + ++ + + G+ T + Sbjct: 125 --DHADYGFPSCEGKFNWRVIKEKRDAYVSRLNAIYQNNLTKSHIEIIRGHAAFTSDPKP 182 Query: 163 TATKADGGTQVIDTKNILIATGS-----EVTPFPGITIDEDTIVSSTGALSLKKVPEKMV 217 T + + +ILIATG + PG ++ ++S G L+++P + V Sbjct: 183 TIEVSG---KKYTAPHILIATGGMPSTPHESQIPGASLG----ITSDGFFQLEELPGRSV 235 Query: 218 VIGAGVIGVELGSVWQRLGADVTAVEFLGHVGGV-GIDMEISKNFQRILQKQGFKFKLNT 276 ++GAG I VE+ + LG+ + + + H + D IS N L+ G + + Sbjct: 236 IVGAGYIAVEMAGILSALGSKTSLM--IRHDKVLRSFDSMISTNCTEELENAGVEVLKFS 293 Query: 277 KVTGATKKSDGKIDVSIEAASGGKAEVITC----DVLLVCIGRRPFTKNLGLEELGIELD 332 +V K G ++VS+ A G+ V+T D LL IGR P TK+L L +LGI+ D Sbjct: 294 QVKEVKKTLSG-LEVSMVTAVPGRLPVMTMIPDVDCLLWAIGRVPNTKDLSLNKLGIQTD 352 Query: 333 PRGRIPVNTRFQTKIPNIYAIGDV-----------VAGPMLAHK----AEDEGIICVEGM 377 +G I V+ T + IYA+GDV AG LAH+ ED Sbjct: 353 DKGHIIVDEFQNTNVKGIYAVGDVCGKALLTPVAIAAGRKLAHRLFEYKEDS-------- 404 Query: 378 AGGAVHIDYNCVPSVIYTHPEVAWVGKSE-EQLKEEGIE-YKVGKFPFAANSRAKTNADT 435 +DYN +P+V+++HP + VG +E E + + GIE K F A T T Sbjct: 405 -----KLDYNNIPTVVFSHPPIGTVGLTEDEAIHKYGIENVKTYSTSFTPMYHAVTKRKT 459 Query: 436 DGMVKILGQKSTDRVLGAHILGPGAGEMVNEAALALEYGASCEDIARVCHAHPTLSE 492 ++K++ ++V+G H+ G G EM+ A+A++ GA+ D HPT SE Sbjct: 460 KCVMKMVCANKEEKVVGIHMQGLGCDEMLQGFAVAVKMGATKADFDNTVAIHPTSSE 516 >gi|22035672 thioredoxin reductase 2 precursor [Homo sapiens] Length = 524 Score = 179 bits (455), Expect = 4e-45 Identities = 144/470 (30%), Positives = 225/470 (47%), Gaps = 24/470 (5%) Query: 41 DADVTVIGSGPGGYVAAIKAAQLGFKTVCIEKNET--------LGGTCLNVGCIPSKALL 92 D D+ V+G G GG A +AAQLG K ++ E LGGTC+NVGCIP K + Sbjct: 39 DYDLLVVGGGSGGLACAKEAAQLGRKVAVVDYVEPSPQGTRWGLGGTCVNVGCIPKKLM- 97 Query: 93 NNSHYYHMAHG--KDFASRGIEMSE-VRLNLDKMMEQKSTAVKALTGGIAHLFKQNKVVH 149 H + G +D + G E+++ V + KM E VK+L G + KV + Sbjct: 98 ---HQAALLGGLIQDAPNYGWEVAQPVPHDWRKMAEAVQNHVKSLNWGHRVQLQDRKVKY 154 Query: 150 VNGYGKITGKNQVTATKADGGTQVIDTKNILIATGSEVTPFPGITIDEDTIVSSTGALSL 209 N ++ V G ++ +I+IATG I + ++S L Sbjct: 155 FNIKASFVDEHTVCGVAKGGKEILLSADHIIIATGGRPRYPTHIEGALEYGITSDDIFWL 214 Query: 210 KKVPEKMVVIGAGVIGVELGSVWQRLGADVTAVEFLGHVGGVGIDMEISKNFQRILQKQG 269 K+ P K +V+GA + +E +G D T + + + G D ++S + G Sbjct: 215 KESPGKTLVVGASYVALECAGFLTGIGLDTTIM--MRSIPLRGFDQQMSSMVIEHMASHG 272 Query: 270 FKFKLNTKVTGATKKSDGKIDVSIEAASGGKAEVITCDVLLVCIGRRPFTKNLGLEELGI 329 +F + + DG++ V+ E ++ GK + T D +L IGR P T++L LE+ G+ Sbjct: 273 TRFLRGCAPSRVRRLPDGQLQVTWEDSTTGKEDTGTFDTVLWAIGRVPDTRSLNLEKAGV 332 Query: 330 ELDP-RGRIPVNTRFQTKIPNIYAIGDVVAG-PMLAHKAEDEGIICVEGMAGGAVHI-DY 386 + P +I V++R T +P+IYAIGDVV G P L A G + V+ + GG+ + DY Sbjct: 333 DTSPDTQKILVDSREATSVPHIYAIGDVVEGRPELTPIAIMAGRLLVQRLFGGSSDLMDY 392 Query: 387 NCVPSVIYTHPEVAWVGKSEEQL----KEEGIEYKVGKFPFAANSRAKTNADTDGMVKIL 442 + VP+ ++T E VG SEE+ +E +E + + A +A + + Sbjct: 393 DNVPTTVFTPLEYGCVGLSEEEAVARHGQEHVEVYHAHYKPLEFTVAGRDASQCYVKMVC 452 Query: 443 GQKSTDRVLGAHILGPGAGEMVNEAALALEYGASCEDIARVCHAHPTLSE 492 ++ VLG H LGP AGE+ AL ++ GAS + R HPT SE Sbjct: 453 LREPPQLVLGLHFLGPNAGEVTQGFALGIKCGASYAQVMRTVGIHPTCSE 502 >gi|226437568 apoptosis-inducing factor, mitochondrion-associated, 3 isoform 3 [Homo sapiens] Length = 604 Score = 64.3 bits (155), Expect = 2e-10 Identities = 44/146 (30%), Positives = 73/146 (50%), Gaps = 7/146 (4%) Query: 216 MVVIGAGVIGVELGSVWQRLGADVTAVEFLGHVGGVGIDMEISKNFQRILQKQGFKFKLN 275 +VV+GAG +G+E+ + V+ VE + + + ++ + KF + Sbjct: 341 VVVVGAGFLGMEVAAYLTEKAHSVSVVELEETPFRRFLGERVGRALMKMFENNRVKFYMQ 400 Query: 276 TKVTGATKKSDGKIDVSIEAASGGKAEVITCDVLLVCIGRRPFTKNLGLEELGIELDPRG 335 T+V+ + +GK+ + +S +V+ DV +V IG P T L + GI LD RG Sbjct: 401 TEVS-ELRGQEGKLKEVVLKSS----KVVRADVCVVGIGAVPATGFL--RQSGIGLDSRG 453 Query: 336 RIPVNTRFQTKIPNIYAIGDVVAGPM 361 IPVN QT +P ++A GD V P+ Sbjct: 454 FIPVNKMMQTNVPGVFAAGDAVTFPL 479 >gi|65787454 apoptosis-inducing factor, mitochondrion-associated, 3 isoform 2 [Homo sapiens] Length = 598 Score = 64.3 bits (155), Expect = 2e-10 Identities = 44/146 (30%), Positives = 73/146 (50%), Gaps = 7/146 (4%) Query: 216 MVVIGAGVIGVELGSVWQRLGADVTAVEFLGHVGGVGIDMEISKNFQRILQKQGFKFKLN 275 +VV+GAG +G+E+ + V+ VE + + + ++ + KF + Sbjct: 335 VVVVGAGFLGMEVAAYLTEKAHSVSVVELEETPFRRFLGERVGRALMKMFENNRVKFYMQ 394 Query: 276 TKVTGATKKSDGKIDVSIEAASGGKAEVITCDVLLVCIGRRPFTKNLGLEELGIELDPRG 335 T+V+ + +GK+ + +S +V+ DV +V IG P T L + GI LD RG Sbjct: 395 TEVS-ELRGQEGKLKEVVLKSS----KVVRADVCVVGIGAVPATGFL--RQSGIGLDSRG 447 Query: 336 RIPVNTRFQTKIPNIYAIGDVVAGPM 361 IPVN QT +P ++A GD V P+ Sbjct: 448 FIPVNKMMQTNVPGVFAAGDAVTFPL 473 >gi|21389617 apoptosis-inducing factor, mitochondrion-associated, 3 isoform 1 [Homo sapiens] Length = 605 Score = 64.3 bits (155), Expect = 2e-10 Identities = 44/146 (30%), Positives = 73/146 (50%), Gaps = 7/146 (4%) Query: 216 MVVIGAGVIGVELGSVWQRLGADVTAVEFLGHVGGVGIDMEISKNFQRILQKQGFKFKLN 275 +VV+GAG +G+E+ + V+ VE + + + ++ + KF + Sbjct: 335 VVVVGAGFLGMEVAAYLTEKAHSVSVVELEETPFRRFLGERVGRALMKMFENNRVKFYMQ 394 Query: 276 TKVTGATKKSDGKIDVSIEAASGGKAEVITCDVLLVCIGRRPFTKNLGLEELGIELDPRG 335 T+V+ + +GK+ + +S +V+ DV +V IG P T L + GI LD RG Sbjct: 395 TEVS-ELRGQEGKLKEVVLKSS----KVVRADVCVVGIGAVPATGFL--RQSGIGLDSRG 447 Query: 336 RIPVNTRFQTKIPNIYAIGDVVAGPM 361 IPVN QT +P ++A GD V P+ Sbjct: 448 FIPVNKMMQTNVPGVFAAGDAVTFPL 473 >gi|229577391 pyridine nucleotide-disulphide oxidoreductase domain 2 [Homo sapiens] Length = 581 Score = 37.0 bits (84), Expect = 0.043 Identities = 21/78 (26%), Positives = 34/78 (43%) Query: 43 DVTVIGSGPGGYVAAIKAAQLGFKTVCIEKNETLGGTCLNVGCIPSKALLNNSHYYHMAH 102 D VIG+G G VAA +LG T E+ +GG + IP S+ + Sbjct: 36 DAVVIGAGHNGLVAAAYLQRLGVNTAVFERRHVIGGAAVTEEIIPGFKFSRASYLLSLLR 95 Query: 103 GKDFASRGIEMSEVRLNL 120 + + ++ +RL+L Sbjct: 96 PQIYTDLELKKHGLRLHL 113 Score = 30.8 bits (68), Expect = 3.0 Identities = 24/75 (32%), Positives = 32/75 (42%), Gaps = 6/75 (8%) Query: 188 TPFPGITIDEDTIVSSTGALSLKKVPEKMVVIGAGVIGVELGSVWQRLGADVTAVEFLGH 247 +PFP D +T A K VVIGAG G+ + QRLG + E Sbjct: 15 SPFPAWRRD------NTEARGGLKPEYDAVVIGAGHNGLVAAAYLQRLGVNTAVFERRHV 68 Query: 248 VGGVGIDMEISKNFQ 262 +GG + EI F+ Sbjct: 69 IGGAAVTEEIIPGFK 83 >gi|203098013 all-trans-13,14-dihydroretinol saturase [Homo sapiens] Length = 610 Score = 36.6 bits (83), Expect = 0.056 Identities = 19/46 (41%), Positives = 25/46 (54%) Query: 39 PIDADVTVIGSGPGGYVAAIKAAQLGFKTVCIEKNETLGGTCLNVG 84 P DV VIGSG GG AA A+ G + + +E++ GG C G Sbjct: 65 PEKLDVVVIGSGFGGLAAAAILAKAGKRVLVLEQHTKAGGCCHTFG 110 >gi|51036596 pyridine nucleotide-disulphide oxidoreductase domain 1 [Homo sapiens] Length = 500 Score = 36.2 bits (82), Expect = 0.073 Identities = 35/138 (25%), Positives = 59/138 (42%), Gaps = 14/138 (10%) Query: 224 IGVELGSVWQRLGADVTAVEFLGHVGGVGIDMEISKNFQ----RILQKQGFKFKLNTK-V 278 +G LG W G ++ + H + E+ K + RIL+K+ F F + K V Sbjct: 231 VGSALGPDWHE-GLNLKGTKEFSHKIHLETMCEVKKIYLQDEFRILKKKSFTFPRDHKSV 289 Query: 279 TGATKKSDGKIDVSIEAASGGKAEVITCDVLLVCIGRRPFTKNLGLEELGIELDPRGRIP 338 T T+ ++++ E G CD ++ G P + L +L G + Sbjct: 290 TADTEMWPVYVELTNEKIYG-------CDFIVSATGVTPNVEPF-LHGNSFDLGEDGGLK 341 Query: 339 VNTRFQTKIPNIYAIGDV 356 V+ T +P+IYA GD+ Sbjct: 342 VDDHMHTSLPDIYAAGDI 359 >gi|119703746 electron-transferring-flavoprotein dehydrogenase precursor [Homo sapiens] Length = 617 Score = 33.9 bits (76), Expect = 0.36 Identities = 19/55 (34%), Positives = 28/55 (50%), Gaps = 11/55 (20%) Query: 41 DADVTVIGSGPGGYVAAIKAAQLG------FKTVCIEK-----NETLGGTCLNVG 84 +ADV ++G+GP G AA++ QL + +EK TL G CL+ G Sbjct: 68 EADVVIVGAGPAGLSAAVRLKQLAVAHEKDIRVCLVEKAAQIGAHTLSGACLDPG 122 >gi|62865635 squalene epoxidase [Homo sapiens] Length = 574 Score = 32.7 bits (73), Expect = 0.80 Identities = 16/53 (30%), Positives = 29/53 (54%), Gaps = 1/53 (1%) Query: 192 GITIDEDTIVSSTGALSLKKVPE-KMVVIGAGVIGVELGSVWQRLGADVTAVE 243 G I E +++ + S + +++++GAGV+G L +V R G VT +E Sbjct: 101 GTNISETSLIGTAACTSTSSQNDPEVIIVGAGVLGSALAAVLSRDGRKVTVIE 153 >gi|23821023 interleukin 4 induced 1 isoform 1 precursor [Homo sapiens] Length = 567 Score = 32.0 bits (71), Expect = 1.4 Identities = 16/47 (34%), Positives = 25/47 (53%) Query: 204 TGALSLKKVPEKMVVIGAGVIGVELGSVWQRLGADVTAVEFLGHVGG 250 T L+ P++++V+GAGV G+ V G VT +E +GG Sbjct: 50 TWGLNRTLKPQRVIVVGAGVAGLVAAKVLSDAGHKVTILEADNRIGG 96 >gi|27477089 interleukin 4 induced 1 isoform 2 [Homo sapiens] Length = 589 Score = 32.0 bits (71), Expect = 1.4 Identities = 16/47 (34%), Positives = 25/47 (53%) Query: 204 TGALSLKKVPEKMVVIGAGVIGVELGSVWQRLGADVTAVEFLGHVGG 250 T L+ P++++V+GAGV G+ V G VT +E +GG Sbjct: 72 TWGLNRTLKPQRVIVVGAGVAGLVAAKVLSDAGHKVTILEADNRIGG 118 >gi|58761544 amine oxidase (flavin containing) domain 2 isoform a [Homo sapiens] Length = 876 Score = 32.0 bits (71), Expect = 1.4 Identities = 15/36 (41%), Positives = 21/36 (58%) Query: 215 KMVVIGAGVIGVELGSVWQRLGADVTAVEFLGHVGG 250 K+++IG+GV G+ Q G DVT +E VGG Sbjct: 300 KVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGG 335 >gi|58761546 amine oxidase (flavin containing) domain 2 isoform b [Homo sapiens] Length = 852 Score = 32.0 bits (71), Expect = 1.4 Identities = 15/36 (41%), Positives = 21/36 (58%) Query: 215 KMVVIGAGVIGVELGSVWQRLGADVTAVEFLGHVGG 250 K+++IG+GV G+ Q G DVT +E VGG Sbjct: 280 KVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGG 315 >gi|38016947 complement component 5 preproprotein [Homo sapiens] Length = 1676 Score = 31.2 bits (69), Expect = 2.3 Identities = 29/119 (24%), Positives = 51/119 (42%), Gaps = 21/119 (17%) Query: 289 IDVSIEAASGGKAEVITCDVLLVCIGRRPFTKNLGLEELGIELDPRG------------- 335 I+ S+E G + V T V+ + R ++ G+ LDPRG Sbjct: 910 INFSLETWFGKEILVKTLRVVPEGVKRESYS--------GVTLDPRGIYGTISRRKEFPY 961 Query: 336 RIPVNTRFQTKIPNIYAIGDVVAGPMLAHKAEDEGIICVEGMAGGAVHIDYNCVPSVIY 394 RIP++ +T+I I ++ ++ G +L+ EGI + + G+ + V V Y Sbjct: 962 RIPLDLVPKTEIKRILSVKGLLVGEILSAVLSQEGINILTHLPKGSAEAELMSVVPVFY 1020 >gi|116256451 amine oxidase (flavin containing) domain 1 [Homo sapiens] Length = 590 Score = 31.2 bits (69), Expect = 2.3 Identities = 13/35 (37%), Positives = 19/35 (54%) Query: 44 VTVIGSGPGGYVAAIKAAQLGFKTVCIEKNETLGG 78 V +IG+GP G AA + G K +E + +GG Sbjct: 253 VIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGG 287 >gi|133908616 glycerol-3-phosphate dehydrogenase 2, mitochondrial [Homo sapiens] Length = 727 Score = 30.4 bits (67), Expect = 4.0 Identities = 14/37 (37%), Positives = 20/37 (54%) Query: 43 DVTVIGSGPGGYVAAIKAAQLGFKTVCIEKNETLGGT 79 D+ VIG G G A+ A G KT +E+++ GT Sbjct: 71 DILVIGGGATGSGCALDAVTRGLKTALVERDDFSSGT 107 >gi|133908614 glycerol-3-phosphate dehydrogenase 2, mitochondrial [Homo sapiens] Length = 727 Score = 30.4 bits (67), Expect = 4.0 Identities = 14/37 (37%), Positives = 20/37 (54%) Query: 43 DVTVIGSGPGGYVAAIKAAQLGFKTVCIEKNETLGGT 79 D+ VIG G G A+ A G KT +E+++ GT Sbjct: 71 DILVIGGGATGSGCALDAVTRGLKTALVERDDFSSGT 107 >gi|7662284 microtubule associated monoxygenase, calponin and LIM domain containing 2 [Homo sapiens] Length = 1124 Score = 30.4 bits (67), Expect = 4.0 Identities = 13/30 (43%), Positives = 19/30 (63%) Query: 46 VIGSGPGGYVAAIKAAQLGFKTVCIEKNET 75 ++G GP G AI+ A LG K V +EK ++ Sbjct: 91 IVGGGPCGLRTAIELAYLGAKVVVVEKRDS 120 >gi|156416003 succinate dehydrogenase complex, subunit A, flavoprotein precursor [Homo sapiens] Length = 664 Score = 30.0 bits (66), Expect = 5.2 Identities = 12/30 (40%), Positives = 17/30 (56%) Query: 43 DVTVIGSGPGGYVAAIKAAQLGFKTVCIEK 72 D V+G+G G AA ++ GF T C+ K Sbjct: 63 DAVVVGAGGAGLRAAFGLSEAGFNTACVTK 92 >gi|18105007 carbamoylphosphate synthetase 2/aspartate transcarbamylase/dihydroorotase [Homo sapiens] Length = 2225 Score = 30.0 bits (66), Expect = 5.2 Identities = 39/150 (26%), Positives = 69/150 (46%), Gaps = 13/150 (8%) Query: 147 VVHVNGYG-KITGKNQVTATKADGGTQVIDTKNILIATGSEVTPFPGITIDEDTIVSSTG 205 +VH G ++TG + D +VI+ N+ + S PF T+ D + +T Sbjct: 1185 IVHAVGQELQVTGPFNLQLIAKDDQLKVIEC-NVRV---SRSFPFVSKTLGVDLVALATR 1240 Query: 206 ALSLKKVPEKMVVIGAGVIGVELG--SVWQRLGADVT-AVEF--LGHVGGVGIDMEISKN 260 + ++V ++ G+GV+GV++ S + GADV VE G V G G + Sbjct: 1241 VIMGEEVEPVGLMTGSGVVGVKVPQFSFSRLAGADVVLGVEMTSTGEVAGFGESR--CEA 1298 Query: 261 FQRILQKQGFKF-KLNTKVTGATKKSDGKI 289 + + + GFK K N +T + K+ ++ Sbjct: 1299 YLKAMLSTGFKIPKKNILLTIGSYKNKSEL 1328 >gi|11128041 protocadherin gamma subfamily A, 10 isoform 1 precursor [Homo sapiens] Length = 936 Score = 29.3 bits (64), Expect = 8.9 Identities = 22/66 (33%), Positives = 36/66 (54%), Gaps = 9/66 (13%) Query: 252 GIDMEISKNFQRILQKQGFKFKLNTKVTGATKKSD-------GKIDVSIEAASGGKAEVI 304 G + E++ +F+++ Q KF+LN K TG K S+ G ++ I+A GG A + Sbjct: 276 GANGEVTYSFRKLPDTQLLKFQLN-KYTGEIKISENLDYEETGFYEIEIQAEDGG-AYLA 333 Query: 305 TCDVLL 310 T VL+ Sbjct: 334 TAKVLI 339 >gi|14196448 protocadherin gamma subfamily A, 10 isoform 2 precursor [Homo sapiens] Length = 850 Score = 29.3 bits (64), Expect = 8.9 Identities = 22/66 (33%), Positives = 36/66 (54%), Gaps = 9/66 (13%) Query: 252 GIDMEISKNFQRILQKQGFKFKLNTKVTGATKKSD-------GKIDVSIEAASGGKAEVI 304 G + E++ +F+++ Q KF+LN K TG K S+ G ++ I+A GG A + Sbjct: 276 GANGEVTYSFRKLPDTQLLKFQLN-KYTGEIKISENLDYEETGFYEIEIQAEDGG-AYLA 333 Query: 305 TCDVLL 310 T VL+ Sbjct: 334 TAKVLI 339 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.317 0.135 0.394 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 18,534,603 Number of Sequences: 37866 Number of extensions: 807488 Number of successful extensions: 1739 Number of sequences better than 10.0: 29 Number of HSP's better than 10.0 without gapping: 24 Number of HSP's successfully gapped in prelim test: 5 Number of HSP's that attempted gapping in prelim test: 1646 Number of HSP's gapped (non-prelim): 43 length of query: 509 length of database: 18,247,518 effective HSP length: 107 effective length of query: 402 effective length of database: 14,195,856 effective search space: 5706734112 effective search space used: 5706734112 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.