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Search of human proteins with 90652861
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|90652861 protein-tyrosine-phosphatase non-receptor 5 isoform
b [Homo sapiens]
(533 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|90652861 protein-tyrosine-phosphatase non-receptor 5 isoform ... 1108 0.0
gi|90652859 protein-tyrosine-phosphatase non-receptor 5 isoform ... 1091 0.0
gi|90652853 protein-tyrosine-phosphatase non-receptor 5 isoform ... 1091 0.0
gi|4506325 protein tyrosine phosphatase, receptor type, R isofor... 410 e-114
gi|19743917 protein tyrosine phosphatase, receptor type, R isofo... 407 e-113
gi|18375660 protein tyrosine phosphatase, non-receptor type 7 is... 332 4e-91
gi|18375658 protein tyrosine phosphatase, non-receptor type 7 is... 332 5e-91
gi|18860902 protein tyrosine phosphatase, receptor type, K isofo... 189 7e-48
gi|148539860 protein tyrosine phosphatase, receptor type, T isof... 189 7e-48
gi|148539858 protein tyrosine phosphatase, receptor type, T isof... 189 7e-48
gi|157419150 protein tyrosine phosphatase, receptor type, M isof... 182 5e-46
gi|157419152 protein tyrosine phosphatase, receptor type, M isof... 182 5e-46
gi|208431815 protein tyrosine phosphatase, receptor type, K isof... 182 7e-46
gi|109633041 protein tyrosine phosphatase, receptor type, F isof... 180 3e-45
gi|109633039 protein tyrosine phosphatase, receptor type, F isof... 180 3e-45
gi|194097398 protein tyrosine phosphatase, receptor type, G prec... 175 1e-43
gi|18104993 protein tyrosine phosphatase, non-receptor type 6 is... 175 1e-43
gi|18104989 protein tyrosine phosphatase, non-receptor type 6 is... 175 1e-43
gi|18104991 protein tyrosine phosphatase, non-receptor type 6 is... 175 1e-43
gi|33356177 protein tyrosine phosphatase, non-receptor type 11 [... 174 2e-43
gi|104487611 protein tyrosine phosphatase, receptor type, sigma ... 174 2e-43
gi|104487297 protein tyrosine phosphatase, receptor type, sigma ... 174 2e-43
gi|104487295 protein tyrosine phosphatase, receptor type, sigma ... 174 2e-43
gi|104487006 protein tyrosine phosphatase, receptor type, sigma ... 174 2e-43
gi|104487002 protein tyrosine phosphatase, receptor type, D isof... 173 4e-43
gi|4506309 protein tyrosine phosphatase, receptor type, D isofor... 173 4e-43
gi|18860890 protein tyrosine phosphatase, receptor type, D isofo... 173 4e-43
gi|18860892 protein tyrosine phosphatase, receptor type, D isofo... 173 4e-43
gi|18860894 protein tyrosine phosphatase, receptor type, D isofo... 173 4e-43
gi|91208428 protein tyrosine phosphatase, receptor-type, zeta1 p... 171 2e-42
>gi|90652861 protein-tyrosine-phosphatase non-receptor 5 isoform b
[Homo sapiens]
Length = 533
Score = 1108 bits (2865), Expect = 0.0
Identities = 533/533 (100%), Positives = 533/533 (100%)
Query: 1 MNYEGARSERENHAADDSEGGALDMCCSERLPGLPQPIVMEALDEAEGLQDSQREMPPPP 60
MNYEGARSERENHAADDSEGGALDMCCSERLPGLPQPIVMEALDEAEGLQDSQREMPPPP
Sbjct: 1 MNYEGARSERENHAADDSEGGALDMCCSERLPGLPQPIVMEALDEAEGLQDSQREMPPPP 60
Query: 61 PPSPPSDPAQKPPPRGAGSHSLTVRSSLCLFAASQFLLEPTAWLDSGTWGVPSLLLVFLS 120
PPSPPSDPAQKPPPRGAGSHSLTVRSSLCLFAASQFLLEPTAWLDSGTWGVPSLLLVFLS
Sbjct: 61 PPSPPSDPAQKPPPRGAGSHSLTVRSSLCLFAASQFLLEPTAWLDSGTWGVPSLLLVFLS 120
Query: 121 VGLVLVTTLVWHLLRTPPEPPTPLPPEDRRQSVSRQPSFTYSEWMEEKIEDDFLDLDPVP 180
VGLVLVTTLVWHLLRTPPEPPTPLPPEDRRQSVSRQPSFTYSEWMEEKIEDDFLDLDPVP
Sbjct: 121 VGLVLVTTLVWHLLRTPPEPPTPLPPEDRRQSVSRQPSFTYSEWMEEKIEDDFLDLDPVP 180
Query: 181 ETPVFDCVMDIKPEADPTSLTVKSMGLQERRGSNVSLTLDMCTPGCNEEGFGYLMSPREE 240
ETPVFDCVMDIKPEADPTSLTVKSMGLQERRGSNVSLTLDMCTPGCNEEGFGYLMSPREE
Sbjct: 181 ETPVFDCVMDIKPEADPTSLTVKSMGLQERRGSNVSLTLDMCTPGCNEEGFGYLMSPREE 240
Query: 241 SAREYLLSASRVLQAEELHEKALDPFLLQAEFFEIPMNFVDPKEYDIPGLVRKNRYKTIL 300
SAREYLLSASRVLQAEELHEKALDPFLLQAEFFEIPMNFVDPKEYDIPGLVRKNRYKTIL
Sbjct: 241 SAREYLLSASRVLQAEELHEKALDPFLLQAEFFEIPMNFVDPKEYDIPGLVRKNRYKTIL 300
Query: 301 PNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFWRMVWQEHT 360
PNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFWRMVWQEHT
Sbjct: 301 PNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFWRMVWQEHT 360
Query: 361 PIIVMITNIEEMNEKCTEYWPEEQVAYDGVEITVQKVIHTEDYRLRLISLKSGTEERGLK 420
PIIVMITNIEEMNEKCTEYWPEEQVAYDGVEITVQKVIHTEDYRLRLISLKSGTEERGLK
Sbjct: 361 PIIVMITNIEEMNEKCTEYWPEEQVAYDGVEITVQKVIHTEDYRLRLISLKSGTEERGLK 420
Query: 421 HYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGIGRTGCFIATSIC 480
HYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGIGRTGCFIATSIC
Sbjct: 421 HYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGIGRTGCFIATSIC 480
Query: 481 CQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVMSLYEKQLSHQSPE 533
CQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVMSLYEKQLSHQSPE
Sbjct: 481 CQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVMSLYEKQLSHQSPE 533
>gi|90652859 protein-tyrosine-phosphatase non-receptor 5 isoform a
[Homo sapiens]
Length = 565
Score = 1091 bits (2822), Expect = 0.0
Identities = 533/565 (94%), Positives = 533/565 (94%), Gaps = 32/565 (5%)
Query: 1 MNYEGARSERENHAADDSEGGALDMCCSERLPGLPQPIVMEALDEAEGLQDSQREMPPPP 60
MNYEGARSERENHAADDSEGGALDMCCSERLPGLPQPIVMEALDEAEGLQDSQREMPPPP
Sbjct: 1 MNYEGARSERENHAADDSEGGALDMCCSERLPGLPQPIVMEALDEAEGLQDSQREMPPPP 60
Query: 61 PPSPPSDPAQKPPPRGAGSHSLTVRSSLCLFAASQFL----------------------- 97
PPSPPSDPAQKPPPRGAGSHSLTVRSSLCLFAASQFL
Sbjct: 61 PPSPPSDPAQKPPPRGAGSHSLTVRSSLCLFAASQFLLACGVLWFSGYGHIWSQNATNLV 120
Query: 98 ---------LEPTAWLDSGTWGVPSLLLVFLSVGLVLVTTLVWHLLRTPPEPPTPLPPED 148
LEPTAWLDSGTWGVPSLLLVFLSVGLVLVTTLVWHLLRTPPEPPTPLPPED
Sbjct: 121 SSLLTLLKQLEPTAWLDSGTWGVPSLLLVFLSVGLVLVTTLVWHLLRTPPEPPTPLPPED 180
Query: 149 RRQSVSRQPSFTYSEWMEEKIEDDFLDLDPVPETPVFDCVMDIKPEADPTSLTVKSMGLQ 208
RRQSVSRQPSFTYSEWMEEKIEDDFLDLDPVPETPVFDCVMDIKPEADPTSLTVKSMGLQ
Sbjct: 181 RRQSVSRQPSFTYSEWMEEKIEDDFLDLDPVPETPVFDCVMDIKPEADPTSLTVKSMGLQ 240
Query: 209 ERRGSNVSLTLDMCTPGCNEEGFGYLMSPREESAREYLLSASRVLQAEELHEKALDPFLL 268
ERRGSNVSLTLDMCTPGCNEEGFGYLMSPREESAREYLLSASRVLQAEELHEKALDPFLL
Sbjct: 241 ERRGSNVSLTLDMCTPGCNEEGFGYLMSPREESAREYLLSASRVLQAEELHEKALDPFLL 300
Query: 269 QAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIR 328
QAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIR
Sbjct: 301 QAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIR 360
Query: 329 GYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEMNEKCTEYWPEEQVAYD 388
GYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEMNEKCTEYWPEEQVAYD
Sbjct: 361 GYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEMNEKCTEYWPEEQVAYD 420
Query: 389 GVEITVQKVIHTEDYRLRLISLKSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEE 448
GVEITVQKVIHTEDYRLRLISLKSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEE
Sbjct: 421 GVEITVQKVIHTEDYRLRLISLKSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEE 480
Query: 449 AAQQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQ 508
AAQQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQ
Sbjct: 481 AAQQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQ 540
Query: 509 TCEQYQFVHHVMSLYEKQLSHQSPE 533
TCEQYQFVHHVMSLYEKQLSHQSPE
Sbjct: 541 TCEQYQFVHHVMSLYEKQLSHQSPE 565
>gi|90652853 protein-tyrosine-phosphatase non-receptor 5 isoform a
[Homo sapiens]
Length = 565
Score = 1091 bits (2822), Expect = 0.0
Identities = 533/565 (94%), Positives = 533/565 (94%), Gaps = 32/565 (5%)
Query: 1 MNYEGARSERENHAADDSEGGALDMCCSERLPGLPQPIVMEALDEAEGLQDSQREMPPPP 60
MNYEGARSERENHAADDSEGGALDMCCSERLPGLPQPIVMEALDEAEGLQDSQREMPPPP
Sbjct: 1 MNYEGARSERENHAADDSEGGALDMCCSERLPGLPQPIVMEALDEAEGLQDSQREMPPPP 60
Query: 61 PPSPPSDPAQKPPPRGAGSHSLTVRSSLCLFAASQFL----------------------- 97
PPSPPSDPAQKPPPRGAGSHSLTVRSSLCLFAASQFL
Sbjct: 61 PPSPPSDPAQKPPPRGAGSHSLTVRSSLCLFAASQFLLACGVLWFSGYGHIWSQNATNLV 120
Query: 98 ---------LEPTAWLDSGTWGVPSLLLVFLSVGLVLVTTLVWHLLRTPPEPPTPLPPED 148
LEPTAWLDSGTWGVPSLLLVFLSVGLVLVTTLVWHLLRTPPEPPTPLPPED
Sbjct: 121 SSLLTLLKQLEPTAWLDSGTWGVPSLLLVFLSVGLVLVTTLVWHLLRTPPEPPTPLPPED 180
Query: 149 RRQSVSRQPSFTYSEWMEEKIEDDFLDLDPVPETPVFDCVMDIKPEADPTSLTVKSMGLQ 208
RRQSVSRQPSFTYSEWMEEKIEDDFLDLDPVPETPVFDCVMDIKPEADPTSLTVKSMGLQ
Sbjct: 181 RRQSVSRQPSFTYSEWMEEKIEDDFLDLDPVPETPVFDCVMDIKPEADPTSLTVKSMGLQ 240
Query: 209 ERRGSNVSLTLDMCTPGCNEEGFGYLMSPREESAREYLLSASRVLQAEELHEKALDPFLL 268
ERRGSNVSLTLDMCTPGCNEEGFGYLMSPREESAREYLLSASRVLQAEELHEKALDPFLL
Sbjct: 241 ERRGSNVSLTLDMCTPGCNEEGFGYLMSPREESAREYLLSASRVLQAEELHEKALDPFLL 300
Query: 269 QAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIR 328
QAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIR
Sbjct: 301 QAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIR 360
Query: 329 GYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEMNEKCTEYWPEEQVAYD 388
GYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEMNEKCTEYWPEEQVAYD
Sbjct: 361 GYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEMNEKCTEYWPEEQVAYD 420
Query: 389 GVEITVQKVIHTEDYRLRLISLKSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEE 448
GVEITVQKVIHTEDYRLRLISLKSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEE
Sbjct: 421 GVEITVQKVIHTEDYRLRLISLKSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEE 480
Query: 449 AAQQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQ 508
AAQQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQ
Sbjct: 481 AAQQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQ 540
Query: 509 TCEQYQFVHHVMSLYEKQLSHQSPE 533
TCEQYQFVHHVMSLYEKQLSHQSPE
Sbjct: 541 TCEQYQFVHHVMSLYEKQLSHQSPE 565
>gi|4506325 protein tyrosine phosphatase, receptor type, R isoform 1
precursor [Homo sapiens]
Length = 657
Score = 410 bits (1054), Expect = e-114
Identities = 226/445 (50%), Positives = 291/445 (65%), Gaps = 28/445 (6%)
Query: 103 WLDSGTWGVPSLLLVFLSVGLVLVTTLVWHLLRTPPEPPTPLPPE-DRRQSVSRQPSFTY 161
W G + V ++FLS+ +++VT L+ L R L + ++ Q + P
Sbjct: 223 WSKEGFYAV----VIFLSIFVIIVTCLMI-LYRLKERFQLSLRQDKEKNQEIHLSPITLQ 277
Query: 162 SEWMEEKIEDDFLDLDPVPETPVFDCVMDIK----PEADPTSLT--------VKSMGLQE 209
E K + + P+ V + V+D + PE T+ T +K +GLQE
Sbjct: 278 PALSEAKTVHSMVQPEQAPK--VLNVVVDPQGRGAPEIRATTATSVCPSPFKMKPIGLQE 335
Query: 210 RRGSNVSLTLDMCTPGCNEEGFGYLMSPREESAREYLLSASRVLQAEELHEKALDPFLLQ 269
RRGSNVSLTLDM + G N E F + +PRE+ A EYL SASR+L +L + LLQ
Sbjct: 336 RRGSNVSLTLDMSSLG-NIEPFVSIPTPREKVAMEYLQSASRILTRSQLRDVVASSHLLQ 394
Query: 270 AEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRG 329
+EF EIPMNFVDPKE DIP KNRYKTILPNP SRVCL + D LS+YINANYIRG
Sbjct: 395 SEFMEIPMNFVDPKEIDIPRHGTKNRYKTILPNPLSRVCLRPKNVTDSLSTYINANYIRG 454
Query: 330 YGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEMNEKCTEYWPEEQVAYDG 389
Y G+EK +IATQGP+++TV DFW+MVWQE +P+IVMIT ++E NEKC YWPE++ Y
Sbjct: 455 YSGKEKAFIATQGPMINTVDDFWQMVWQEDSPVIVMITKLKEKNEKCVLYWPEKRGIYGK 514
Query: 390 VEITVQKVIHTEDYRLRLISLKSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEE- 448
VE+ V V ++Y +R + LK G+ + +KHYW+TSWPD KTPD A PLL L+ +VEE
Sbjct: 515 VEVLVISVNECDNYTIRNLVLKQGSHTQHVKHYWYTSWPDHKTPDSAQPLLQLMLDVEED 574
Query: 449 --AAQQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGM 506
A+Q G P++VHCSAGIGRTGCFIATSI CQQL++EGVVD L CQLR DRGGM
Sbjct: 575 RLASQGRG----PVVVHCSAGIGRTGCFIATSIGCQQLKEEGVVDALSIVCQLRMDRGGM 630
Query: 507 IQTCEQYQFVHHVMSLYEKQLSHQS 531
+QT EQY+FVHH + LYE +LS ++
Sbjct: 631 VQTSEQYEFVHHALCLYESRLSAET 655
>gi|19743917 protein tyrosine phosphatase, receptor type, R isoform
2 [Homo sapiens]
Length = 412
Score = 407 bits (1045), Expect = e-113
Identities = 203/338 (60%), Positives = 250/338 (73%), Gaps = 8/338 (2%)
Query: 197 PTSLTVKSMGLQERRGSNVSLTLDMCTPGCNEEGFGYLMSPREESAREYLLSASRVLQAE 256
P+ +K +GLQERRGSNVSLTLDM + G N E F + +PRE+ A EYL SASR+L
Sbjct: 78 PSPFKMKPIGLQERRGSNVSLTLDMSSLG-NIEPFVSIPTPREKVAMEYLQSASRILTRS 136
Query: 257 ELHEKALDPFLLQAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVCLTSPDPDD 316
+L + LLQ+EF EIPMNFVDPKE DIP KNRYKTILPNP SRVCL + D
Sbjct: 137 QLRDVVASSHLLQSEFMEIPMNFVDPKEIDIPRHGTKNRYKTILPNPLSRVCLRPKNVTD 196
Query: 317 PLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEMNEKC 376
LS+YINANYIRGY G+EK +IATQGP+++TV DFW+MVWQE +P+IVMIT ++E NEKC
Sbjct: 197 SLSTYINANYIRGYSGKEKAFIATQGPMINTVDDFWQMVWQEDSPVIVMITKLKEKNEKC 256
Query: 377 TEYWPEEQVAYDGVEITVQKVIHTEDYRLRLISLKSGTEERGLKHYWFTSWPDQKTPDRA 436
YWPE++ Y VE+ V V ++Y +R + LK G+ + +KHYW+TSWPD KTPD A
Sbjct: 257 VLYWPEKRGIYGKVEVLVISVNECDNYTIRNLVLKQGSHTQHVKHYWYTSWPDHKTPDSA 316
Query: 437 PPLLHLVREVEE---AAQQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGVVDIL 493
PLL L+ +VEE A+Q G P++VHCSAGIGRTGCFIATSI CQQL++EGVVD L
Sbjct: 317 QPLLQLMLDVEEDRLASQGRG----PVVVHCSAGIGRTGCFIATSIGCQQLKEEGVVDAL 372
Query: 494 KTTCQLRQDRGGMIQTCEQYQFVHHVMSLYEKQLSHQS 531
CQLR DRGGM+QT EQY+FVHH + LYE +LS ++
Sbjct: 373 SIVCQLRMDRGGMVQTSEQYEFVHHALCLYESRLSAET 410
>gi|18375660 protein tyrosine phosphatase, non-receptor type 7
isoform 2 [Homo sapiens]
Length = 399
Score = 332 bits (852), Expect = 4e-91
Identities = 184/401 (45%), Positives = 238/401 (59%), Gaps = 26/401 (6%)
Query: 145 PPEDRRQSVSRQPSFTYSEWMEEKIEDDFLDLDPVPETPVFDCVMDIKPEADPTSLTV-- 202
P R+ R SF + W+ E L P P + + A P +L++
Sbjct: 7 PIRQAREQQRRALSFRQTSWLSEP------PLGPAPHLSMVQAHGG-RSRAQPLTLSLGA 59
Query: 203 -------------KSMGLQERRGSNVSLTLDMCTPGCNEEGFGYLMSPREESAREYLLSA 249
K + LQERRGSNV+L LD+ + G E + +PRE + +L +A
Sbjct: 60 AMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEP-ICSVNTPREVTLH-FLRTA 117
Query: 250 SRVLQAEELHEKALDPFLLQAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVCL 309
L L + P L+ EF +IP NFV P++ DIPG K+RYKTILPNP SRVCL
Sbjct: 118 GHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCL 177
Query: 310 TSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNI 369
+ YINANYIRGY G+EKVYIATQGP+ +TV+DFW MVWQE +IVM+T +
Sbjct: 178 GRAQSQED-GDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQL 236
Query: 370 EEMNEKCTEYWPEEQVAYDGVEITVQKVIHTEDYRLRLISLKSGTEERGLKHYWFTSWPD 429
E EKC YWP E+ Y +I +Q + +Y +R ++++ E R +KH F++WPD
Sbjct: 237 REGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPD 296
Query: 430 QKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGV 489
+TP+ A PLL LV EVEE + + H PI+VHCSAGIGRTGCFIAT I CQQL+ G
Sbjct: 297 HQTPESAGPLLRLVAEVEE-SPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGE 355
Query: 490 VDILKTTCQLRQDRGGMIQTCEQYQFVHHVMSLYEKQLSHQ 530
VDIL CQLR DRGGMIQT EQYQF+HH ++LY QL +
Sbjct: 356 VDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEE 396
>gi|18375658 protein tyrosine phosphatase, non-receptor type 7
isoform 1 [Homo sapiens]
Length = 360
Score = 332 bits (851), Expect = 5e-91
Identities = 174/338 (51%), Positives = 220/338 (65%), Gaps = 7/338 (2%)
Query: 193 PEADPTSLTVKSMGLQERRGSNVSLTLDMCTPGCNEEGFGYLMSPREESAREYLLSASRV 252
PE P K + LQERRGSNV+L LD+ + G E + +PRE + +L +A
Sbjct: 27 PEKTPAK---KHVRLQERRGSNVALMLDVRSLGAVEP-ICSVNTPREVTLH-FLRTAGHP 81
Query: 253 LQAEELHEKALDPFLLQAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVCLTSP 312
L L + P L+ EF +IP NFV P++ DIPG K+RYKTILPNP SRVCL
Sbjct: 82 LTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRA 141
Query: 313 DPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEM 372
+ YINANYIRGY G+EKVYIATQGP+ +TV+DFW MVWQE +IVM+T + E
Sbjct: 142 QSQED-GDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREG 200
Query: 373 NEKCTEYWPEEQVAYDGVEITVQKVIHTEDYRLRLISLKSGTEERGLKHYWFTSWPDQKT 432
EKC YWP E+ Y +I +Q + +Y +R ++++ E R +KH F++WPD +T
Sbjct: 201 KEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQT 260
Query: 433 PDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGVVDI 492
P+ A PLL LV EVEE + + H PI+VHCSAGIGRTGCFIAT I CQQL+ G VDI
Sbjct: 261 PESAGPLLRLVAEVEE-SPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDI 319
Query: 493 LKTTCQLRQDRGGMIQTCEQYQFVHHVMSLYEKQLSHQ 530
L CQLR DRGGMIQT EQYQF+HH ++LY QL +
Sbjct: 320 LGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEE 357
>gi|18860902 protein tyrosine phosphatase, receptor type, K isoform b
[Homo sapiens]
Length = 1440
Score = 189 bits (479), Expect = 7e-48
Identities = 104/228 (45%), Positives = 132/228 (57%), Gaps = 8/228 (3%)
Query: 293 KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFW 352
KNRY I+ HSRV L P DDP S YINANYI GY YIATQGP+ TV DFW
Sbjct: 914 KNRYGNIIAYDHSRVIL-QPVEDDPSSDYINANYIDGYQRPSH-YIATQGPVHETVYDFW 971
Query: 353 RMVWQEHTPIIVMITNIEEMNE-KCTEYWPEEQVAYDGVEITVQKVIHTEDYRLRLISL- 410
RM+WQE + IVM+TN+ E+ KC +YWP++ Y ++T ++ +Y +R +L
Sbjct: 972 RMIWQEQSACIVMVTNLVEVGRVKCYKYWPDDTEVYGDFKVTCVEMEPLAEYVVRTFTLE 1031
Query: 411 -KSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGIG 469
+ E R +K + FT WPD P A LL +R V+ + P PI+VHCSAG G
Sbjct: 1032 RRGYNEIREVKQFHFTGWPDHGVPYHATGLLSFIRRVKLS---NPPSAGPIVVHCSAGAG 1088
Query: 470 RTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVH 517
RTGC+I I +EGVVDI LR R M+QT EQY F+H
Sbjct: 1089 RTGCYIVIDIMLDMAEREGVVDIYNCVKALRSRRINMVQTEEQYIFIH 1136
Score = 98.2 bits (243), Expect = 2e-20
Identities = 65/237 (27%), Positives = 115/237 (48%), Gaps = 10/237 (4%)
Query: 293 KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFW 352
KNR+ +LP L + D + S+YINA + Y + +I TQ P+ +TV DFW
Sbjct: 1204 KNRFMDMLPPDRCLPFLITIDGES--SNYINAALMDSYR-QPAAFIVTQYPLPNTVKDFW 1260
Query: 353 RMVWQEHTPIIVMITNIEEMNEKCTEYWPEE-QVAYDGVEITVQKVIHTEDYRLRLISLK 411
R+V+ IVM+ ++ +++ C +YWPEE + Y +++ D R+ +
Sbjct: 1261 RLVYDYGCTSIVMLNEVD-LSQGCPQYWPEEGMLRYGPIQVECMSCSMDCDVINRIFRIC 1319
Query: 412 SGTEERG----LKHYWFTSWPDQK-TPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSA 466
+ T + ++ + + W + P L L+ +VE+ ++ I+HC
Sbjct: 1320 NLTRPQEGYLMVQQFQYLGWASHREVPGSKRSFLKLILQVEKWQEECEEGEGRTIIHCLN 1379
Query: 467 GIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVMSLY 523
G GR+G F A I + ++++ VVD+ LR + M++ EQY+F + V Y
Sbjct: 1380 GGGRSGMFCAIGIVVEMVKRQNVVDVFHAVKTLRNSKPNMVEAPEQYRFCYDVALEY 1436
>gi|148539860 protein tyrosine phosphatase, receptor type, T isoform 2
precursor [Homo sapiens]
Length = 1441
Score = 189 bits (479), Expect = 7e-48
Identities = 107/228 (46%), Positives = 135/228 (59%), Gaps = 8/228 (3%)
Query: 293 KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFW 352
KNRY I+ HSRV L D DP S YINANYI GY + YIATQGP+ TV DFW
Sbjct: 915 KNRYGNIISYDHSRVRLLVLD-GDPHSDYINANYIDGYH-RPRHYIATQGPMQETVKDFW 972
Query: 353 RMVWQEHTPIIVMITNIEEMNE-KCTEYWPEEQVAYDGVEITVQKVIHTEDYRLRLISL- 410
RM+WQE++ IVM+TN+ E+ KC YWP++ Y +++T+ + +Y +R ++
Sbjct: 973 RMIWQENSASIVMVTNLVEVGRVKCVRYWPDDTEVYGDIKVTLIETEPLAEYVIRTFTVQ 1032
Query: 411 KSGTEE-RGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGIG 469
K G E R L+ + FTSWPD P A LL VR+V+ P PI+VHCSAG G
Sbjct: 1033 KKGYHEIRELRLFHFTSWPDHGVPCYATGLLGFVRQVKFL---NPPEAGPIVVHCSAGAG 1089
Query: 470 RTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVH 517
RTGCFIA EGVVDI +LR R ++QT EQY FVH
Sbjct: 1090 RTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQTEEQYVFVH 1137
Score = 112 bits (279), Expect = 1e-24
Identities = 75/253 (29%), Positives = 126/253 (49%), Gaps = 13/253 (5%)
Query: 280 VDPKEYDIPGLVR---KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKV 336
V P++ I L R KNR +LP L S D + S+YINA + + +
Sbjct: 1189 VRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGES--SNYINAALMDSHK-QPAA 1245
Query: 337 YIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEMNEKCTEYWPEEQVA-YDGVEITVQ 395
++ TQ P+ +TVADFWR+V+ + +VM+ ++ + C +YWPE+ Y +++
Sbjct: 1246 FVVTQHPLPNTVADFWRLVFDYNCSSVVMLNEMDTA-QFCMQYWPEKTSGCYGPIQVEFV 1304
Query: 396 KVIHTEDYRLRLISLKSGTEE----RGLKHYWFTSWPDQK-TPDRAPPLLHLVREVEEAA 450
ED R+ + + R ++H + WP + TP LL +VR +E+
Sbjct: 1305 SADIDEDIIHRIFRICNMARPQDGYRIVQHLQYIGWPAYRDTPPSKRSLLKVVRRLEKWQ 1364
Query: 451 QQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTC 510
+Q +VHC G GR+G F A C+ ++Q+ ++D+ LR ++ M++T
Sbjct: 1365 EQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIVKTLRNNKSNMVETL 1424
Query: 511 EQYQFVHHVMSLY 523
EQY+FV+ V Y
Sbjct: 1425 EQYKFVYEVALEY 1437
>gi|148539858 protein tyrosine phosphatase, receptor type, T isoform 1
precursor [Homo sapiens]
Length = 1460
Score = 189 bits (479), Expect = 7e-48
Identities = 107/228 (46%), Positives = 135/228 (59%), Gaps = 8/228 (3%)
Query: 293 KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFW 352
KNRY I+ HSRV L D DP S YINANYI GY + YIATQGP+ TV DFW
Sbjct: 934 KNRYGNIISYDHSRVRLLVLD-GDPHSDYINANYIDGYH-RPRHYIATQGPMQETVKDFW 991
Query: 353 RMVWQEHTPIIVMITNIEEMNE-KCTEYWPEEQVAYDGVEITVQKVIHTEDYRLRLISL- 410
RM+WQE++ IVM+TN+ E+ KC YWP++ Y +++T+ + +Y +R ++
Sbjct: 992 RMIWQENSASIVMVTNLVEVGRVKCVRYWPDDTEVYGDIKVTLIETEPLAEYVIRTFTVQ 1051
Query: 411 KSGTEE-RGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGIG 469
K G E R L+ + FTSWPD P A LL VR+V+ P PI+VHCSAG G
Sbjct: 1052 KKGYHEIRELRLFHFTSWPDHGVPCYATGLLGFVRQVKFL---NPPEAGPIVVHCSAGAG 1108
Query: 470 RTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVH 517
RTGCFIA EGVVDI +LR R ++QT EQY FVH
Sbjct: 1109 RTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQTEEQYVFVH 1156
Score = 112 bits (279), Expect = 1e-24
Identities = 75/253 (29%), Positives = 126/253 (49%), Gaps = 13/253 (5%)
Query: 280 VDPKEYDIPGLVR---KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKV 336
V P++ I L R KNR +LP L S D + S+YINA + + +
Sbjct: 1208 VRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGES--SNYINAALMDSHK-QPAA 1264
Query: 337 YIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEMNEKCTEYWPEEQVA-YDGVEITVQ 395
++ TQ P+ +TVADFWR+V+ + +VM+ ++ + C +YWPE+ Y +++
Sbjct: 1265 FVVTQHPLPNTVADFWRLVFDYNCSSVVMLNEMDTA-QFCMQYWPEKTSGCYGPIQVEFV 1323
Query: 396 KVIHTEDYRLRLISLKSGTEE----RGLKHYWFTSWPDQK-TPDRAPPLLHLVREVEEAA 450
ED R+ + + R ++H + WP + TP LL +VR +E+
Sbjct: 1324 SADIDEDIIHRIFRICNMARPQDGYRIVQHLQYIGWPAYRDTPPSKRSLLKVVRRLEKWQ 1383
Query: 451 QQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTC 510
+Q +VHC G GR+G F A C+ ++Q+ ++D+ LR ++ M++T
Sbjct: 1384 EQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIVKTLRNNKSNMVETL 1443
Query: 511 EQYQFVHHVMSLY 523
EQY+FV+ V Y
Sbjct: 1444 EQYKFVYEVALEY 1456
>gi|157419150 protein tyrosine phosphatase, receptor type, M isoform 2
precursor [Homo sapiens]
Length = 1452
Score = 182 bits (463), Expect = 5e-46
Identities = 100/228 (43%), Positives = 134/228 (58%), Gaps = 8/228 (3%)
Query: 293 KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFW 352
KNRY I+ HSRV L + + D S YIN NYI GY YIATQGP+ T+ DFW
Sbjct: 926 KNRYGNIIAYDHSRVRLQTIEGDTN-SDYINGNYIDGYHRPNH-YIATQGPMQETIYDFW 983
Query: 353 RMVWQEHTPIIVMITNIEEMNE-KCTEYWPEEQVAYDGVEITVQKVIHTEDYRLRLISL- 410
RMVW E+T I+M+TN+ E+ KC +YWP++ Y +++T+ + +Y +R ++
Sbjct: 984 RMVWHENTASIIMVTNLVEVGRVKCCKYWPDDTEIYKDIKVTLIETELLAEYVIRTFAVE 1043
Query: 411 KSGTEE-RGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGIG 469
K G E R ++ + FT WPD P A LL VR+V+ + P P++VHCSAG G
Sbjct: 1044 KRGVHEIREIRQFHFTGWPDHGVPYHATGLLGFVRQVKSKSP---PSAGPLVVHCSAGAG 1100
Query: 470 RTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVH 517
RTGCFI I +EGVVDI +LR R M+QT EQY F+H
Sbjct: 1101 RTGCFIVIDIMLDMAEREGVVDIYNCVRELRSRRVNMVQTEEQYVFIH 1148
Score = 111 bits (277), Expect = 2e-24
Identities = 73/243 (30%), Positives = 117/243 (48%), Gaps = 10/243 (4%)
Query: 287 IPGLVRKNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVS 346
+P KNR ILP L + D + S+YINA + Y + +I TQ P+ +
Sbjct: 1210 LPRNHEKNRCMDILPPDRCLPFLITIDGES--SNYINAALMDSYK-QPSAFIVTQHPLPN 1266
Query: 347 TVADFWRMVWQEHTPIIVMITNIEEMNEKCTEYWPEEQVAYDG-VEITVQKVIHTEDYRL 405
TV DFWR+V H +VM+ +++ + C +YWPE V G +++ ED
Sbjct: 1267 TVKDFWRLVLDYHCTSVVMLNDVDPA-QLCPQYWPENGVHRHGPIQVEFVSADLEEDIIS 1325
Query: 406 RLISLKSGTEE----RGLKHYWFTSWPDQK-TPDRAPPLLHLVREVEEAAQQEGPHCAPI 460
R+ + + R ++ + F WP + TP L L+R+V++ ++
Sbjct: 1326 RIFRIYNAARPQDGYRMVQQFQFLGWPMYRDTPVSKRSFLKLIRQVDKWQEEYNGGEGRT 1385
Query: 461 IVHCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVM 520
+VHC G GR+G F A SI C+ LR + VD+ LR ++ M+ +QY+F + V
Sbjct: 1386 VVHCLNGGGRSGTFCAISIVCEMLRHQRTVDVFHAVKTLRNNKPNMVDLLDQYKFCYEVA 1445
Query: 521 SLY 523
Y
Sbjct: 1446 LEY 1448
>gi|157419152 protein tyrosine phosphatase, receptor type, M isoform 1
precursor [Homo sapiens]
Length = 1465
Score = 182 bits (463), Expect = 5e-46
Identities = 100/228 (43%), Positives = 134/228 (58%), Gaps = 8/228 (3%)
Query: 293 KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFW 352
KNRY I+ HSRV L + + D S YIN NYI GY YIATQGP+ T+ DFW
Sbjct: 939 KNRYGNIIAYDHSRVRLQTIEGDTN-SDYINGNYIDGYHRPNH-YIATQGPMQETIYDFW 996
Query: 353 RMVWQEHTPIIVMITNIEEMNE-KCTEYWPEEQVAYDGVEITVQKVIHTEDYRLRLISL- 410
RMVW E+T I+M+TN+ E+ KC +YWP++ Y +++T+ + +Y +R ++
Sbjct: 997 RMVWHENTASIIMVTNLVEVGRVKCCKYWPDDTEIYKDIKVTLIETELLAEYVIRTFAVE 1056
Query: 411 KSGTEE-RGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGIG 469
K G E R ++ + FT WPD P A LL VR+V+ + P P++VHCSAG G
Sbjct: 1057 KRGVHEIREIRQFHFTGWPDHGVPYHATGLLGFVRQVKSKSP---PSAGPLVVHCSAGAG 1113
Query: 470 RTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVH 517
RTGCFI I +EGVVDI +LR R M+QT EQY F+H
Sbjct: 1114 RTGCFIVIDIMLDMAEREGVVDIYNCVRELRSRRVNMVQTEEQYVFIH 1161
Score = 111 bits (277), Expect = 2e-24
Identities = 73/243 (30%), Positives = 117/243 (48%), Gaps = 10/243 (4%)
Query: 287 IPGLVRKNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVS 346
+P KNR ILP L + D + S+YINA + Y + +I TQ P+ +
Sbjct: 1223 LPRNHEKNRCMDILPPDRCLPFLITIDGES--SNYINAALMDSYK-QPSAFIVTQHPLPN 1279
Query: 347 TVADFWRMVWQEHTPIIVMITNIEEMNEKCTEYWPEEQVAYDG-VEITVQKVIHTEDYRL 405
TV DFWR+V H +VM+ +++ + C +YWPE V G +++ ED
Sbjct: 1280 TVKDFWRLVLDYHCTSVVMLNDVDPA-QLCPQYWPENGVHRHGPIQVEFVSADLEEDIIS 1338
Query: 406 RLISLKSGTEE----RGLKHYWFTSWPDQK-TPDRAPPLLHLVREVEEAAQQEGPHCAPI 460
R+ + + R ++ + F WP + TP L L+R+V++ ++
Sbjct: 1339 RIFRIYNAARPQDGYRMVQQFQFLGWPMYRDTPVSKRSFLKLIRQVDKWQEEYNGGEGRT 1398
Query: 461 IVHCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVM 520
+VHC G GR+G F A SI C+ LR + VD+ LR ++ M+ +QY+F + V
Sbjct: 1399 VVHCLNGGGRSGTFCAISIVCEMLRHQRTVDVFHAVKTLRNNKPNMVDLLDQYKFCYEVA 1458
Query: 521 SLY 523
Y
Sbjct: 1459 LEY 1461
>gi|208431815 protein tyrosine phosphatase, receptor type, K isoform a
[Homo sapiens]
Length = 1446
Score = 182 bits (462), Expect = 7e-46
Identities = 104/234 (44%), Positives = 132/234 (56%), Gaps = 14/234 (5%)
Query: 293 KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIR------GYGGEEKVYIATQGPIVS 346
KNRY I+ HSRV L P DDP S YINANYI GY YIATQGP+
Sbjct: 914 KNRYGNIIAYDHSRVIL-QPVEDDPSSDYINANYIDIWLYRDGYQRPSH-YIATQGPVHE 971
Query: 347 TVADFWRMVWQEHTPIIVMITNIEEMNE-KCTEYWPEEQVAYDGVEITVQKVIHTEDYRL 405
TV DFWRM+WQE + IVM+TN+ E+ KC +YWP++ Y ++T ++ +Y +
Sbjct: 972 TVYDFWRMIWQEQSACIVMVTNLVEVGRVKCYKYWPDDTEVYGDFKVTCVEMEPLAEYVV 1031
Query: 406 RLISL--KSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVH 463
R +L + E R +K + FT WPD P A LL +R V+ + P PI+VH
Sbjct: 1032 RTFTLERRGYNEIREVKQFHFTGWPDHGVPYHATGLLSFIRRVKLS---NPPSAGPIVVH 1088
Query: 464 CSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVH 517
CSAG GRTGC+I I +EGVVDI LR R M+QT EQY F+H
Sbjct: 1089 CSAGAGRTGCYIVIDIMLDMAEREGVVDIYNCVKALRSRRINMVQTEEQYIFIH 1142
Score = 98.2 bits (243), Expect = 2e-20
Identities = 65/237 (27%), Positives = 115/237 (48%), Gaps = 10/237 (4%)
Query: 293 KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFW 352
KNR+ +LP L + D + S+YINA + Y + +I TQ P+ +TV DFW
Sbjct: 1210 KNRFMDMLPPDRCLPFLITIDGES--SNYINAALMDSYR-QPAAFIVTQYPLPNTVKDFW 1266
Query: 353 RMVWQEHTPIIVMITNIEEMNEKCTEYWPEE-QVAYDGVEITVQKVIHTEDYRLRLISLK 411
R+V+ IVM+ ++ +++ C +YWPEE + Y +++ D R+ +
Sbjct: 1267 RLVYDYGCTSIVMLNEVD-LSQGCPQYWPEEGMLRYGPIQVECMSCSMDCDVINRIFRIC 1325
Query: 412 SGTEERG----LKHYWFTSWPDQK-TPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSA 466
+ T + ++ + + W + P L L+ +VE+ ++ I+HC
Sbjct: 1326 NLTRPQEGYLMVQQFQYLGWASHREVPGSKRSFLKLILQVEKWQEECEEGEGRTIIHCLN 1385
Query: 467 GIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVMSLY 523
G GR+G F A I + ++++ VVD+ LR + M++ EQY+F + V Y
Sbjct: 1386 GGGRSGMFCAIGIVVEMVKRQNVVDVFHAVKTLRNSKPNMVEAPEQYRFCYDVALEY 1442
>gi|109633041 protein tyrosine phosphatase, receptor type, F isoform 1
precursor [Homo sapiens]
Length = 1907
Score = 180 bits (457), Expect = 3e-45
Identities = 96/232 (41%), Positives = 138/232 (59%), Gaps = 9/232 (3%)
Query: 293 KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFW 352
KNRY ++ HSRV LTS D P S YINANYI GY ++ YIATQGP+ T+ DFW
Sbjct: 1378 KNRYANVIAYDHSRVILTSID-GVPGSDYINANYIDGYR-KQNAYIATQGPLPETMGDFW 1435
Query: 353 RMVWQEHTPIIVMITNIEEMNE-KCTEYWPEEQVAYDG-VEITVQKVIHTEDYRLRLISL 410
RMVW++ T +VM+T +EE + KC +YWP G +++T+ + Y +R +L
Sbjct: 1436 RMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGTETCGLIQVTLLDTVELATYTVRTFAL 1495
Query: 411 -KSGT-EERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGI 468
KSG+ E+R L+ + F +WPD P+ P+L +R V+ + P++VHCSAG+
Sbjct: 1496 HKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDA---GPMVVHCSAGV 1552
Query: 469 GRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVM 520
GRTGCFI ++++ E VDI +R R M+QT +QY F+H +
Sbjct: 1553 GRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEAL 1604
Score = 167 bits (424), Expect = 2e-41
Identities = 94/241 (39%), Positives = 133/241 (55%), Gaps = 7/241 (2%)
Query: 293 KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFW 352
KNR I+P +RVCL P S YINA+++ GY ++K YIATQGP+ + DFW
Sbjct: 1667 KNRLVNIMPYELTRVCL-QPIRGVEGSDYINASFLDGYR-QQKAYIATQGPLAESTEDFW 1724
Query: 353 RMVWQEHTPIIVMITNIEEMN-EKCTEYWPEEQVA-YDGVEITVQKVIHTEDYRLRLISL 410
RM+W+ ++ IIVM+T + EM EKC +YWP E+ A Y + + Y LR +
Sbjct: 1725 RMLWEHNSTIIVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKV 1784
Query: 411 KSGTE--ERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGI 468
+ R ++ + FT WP+Q P + + +V + +Q G PI VHCSAG+
Sbjct: 1785 TDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQD-GPITVHCSAGV 1843
Query: 469 GRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVMSLYEKQLS 528
GRTG FI SI +++R EGVVD+ +T LR R M+QT +QYQ + Y
Sbjct: 1844 GRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFD 1903
Query: 529 H 529
H
Sbjct: 1904 H 1904
>gi|109633039 protein tyrosine phosphatase, receptor type, F isoform 2
precursor [Homo sapiens]
Length = 1898
Score = 180 bits (457), Expect = 3e-45
Identities = 96/232 (41%), Positives = 138/232 (59%), Gaps = 9/232 (3%)
Query: 293 KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFW 352
KNRY ++ HSRV LTS D P S YINANYI GY ++ YIATQGP+ T+ DFW
Sbjct: 1369 KNRYANVIAYDHSRVILTSID-GVPGSDYINANYIDGYR-KQNAYIATQGPLPETMGDFW 1426
Query: 353 RMVWQEHTPIIVMITNIEEMNE-KCTEYWPEEQVAYDG-VEITVQKVIHTEDYRLRLISL 410
RMVW++ T +VM+T +EE + KC +YWP G +++T+ + Y +R +L
Sbjct: 1427 RMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGTETCGLIQVTLLDTVELATYTVRTFAL 1486
Query: 411 -KSGT-EERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGI 468
KSG+ E+R L+ + F +WPD P+ P+L +R V+ + P++VHCSAG+
Sbjct: 1487 HKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDA---GPMVVHCSAGV 1543
Query: 469 GRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVM 520
GRTGCFI ++++ E VDI +R R M+QT +QY F+H +
Sbjct: 1544 GRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEAL 1595
Score = 167 bits (424), Expect = 2e-41
Identities = 94/241 (39%), Positives = 133/241 (55%), Gaps = 7/241 (2%)
Query: 293 KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFW 352
KNR I+P +RVCL P S YINA+++ GY ++K YIATQGP+ + DFW
Sbjct: 1658 KNRLVNIMPYELTRVCL-QPIRGVEGSDYINASFLDGYR-QQKAYIATQGPLAESTEDFW 1715
Query: 353 RMVWQEHTPIIVMITNIEEMN-EKCTEYWPEEQVA-YDGVEITVQKVIHTEDYRLRLISL 410
RM+W+ ++ IIVM+T + EM EKC +YWP E+ A Y + + Y LR +
Sbjct: 1716 RMLWEHNSTIIVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKV 1775
Query: 411 KSGTE--ERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGI 468
+ R ++ + FT WP+Q P + + +V + +Q G PI VHCSAG+
Sbjct: 1776 TDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQD-GPITVHCSAGV 1834
Query: 469 GRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVMSLYEKQLS 528
GRTG FI SI +++R EGVVD+ +T LR R M+QT +QYQ + Y
Sbjct: 1835 GRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFD 1894
Query: 529 H 529
H
Sbjct: 1895 H 1895
>gi|194097398 protein tyrosine phosphatase, receptor type, G precursor
[Homo sapiens]
Length = 1445
Score = 175 bits (443), Expect = 1e-43
Identities = 98/244 (40%), Positives = 135/244 (55%), Gaps = 20/244 (8%)
Query: 293 KNRYKTILPNPHSRVCLTS-PDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADF 351
KNRY IL HSRV L P D S YINANY+ GY + K YIATQGP+ ST DF
Sbjct: 877 KNRYINILAYDHSRVKLRPLPGKDSKHSDYINANYVDGYN-KAKAYIATQGPLKSTFEDF 935
Query: 352 WRMVWQEHTPIIVMITN-IEEMNEKCTEYWP-EEQVAYDGVEITVQKVIHTEDYRLRLIS 409
WRM+W+++T IIVMITN +E+ KC +YWP E Y + +T++ Y +R S
Sbjct: 936 WRMIWEQNTGIIVMITNLVEKGRRKCDQYWPTENSEEYGNIIVTLKSTKIHACYTVRRFS 995
Query: 410 LKSGTEERGLK-------------HYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPH 456
+++ ++G K Y +T WPD P+ A P+L VR A P
Sbjct: 996 IRNTKVKKGQKGNPKGRQNERVVIQYHYTQWPDMGVPEYALPVLTFVRRSSAARM---PE 1052
Query: 457 CAPIIVHCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFV 516
P++VHCSAG+GRTG +I QQ++ + V++L +R R ++QT EQY F+
Sbjct: 1053 TGPVLVHCSAGVGRTGTYIVIDSMLQQIKDKSTVNVLGFLKHIRTQRNYLVQTEEQYIFI 1112
Query: 517 HHVM 520
H +
Sbjct: 1113 HDAL 1116
Score = 103 bits (256), Expect = 5e-22
Identities = 70/238 (29%), Positives = 116/238 (48%), Gaps = 18/238 (7%)
Query: 293 KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFW 352
KNR +++P+ +RV L +P P + YINA+YI GY + +I TQ P+ T DFW
Sbjct: 1178 KNRNSSVVPSERARVGL-APLPGMKGTDYINASYIMGYYRSNE-FIITQHPLPHTTKDFW 1235
Query: 353 RMVWQEHTPIIVMITNIEEMNEKCTEYWPEEQVAYDGVEITVQKV------IHTEDYRLR 406
RM+W + IIVM+ + + + E YWP + + + TV + + E+ +
Sbjct: 1236 RMIWDHNAQIIVMLPDNQSLAEDEFVYWPSREESMNCEAFTVTLISKDRLCLSNEEQIII 1295
Query: 407 LISLKSGTEE---RGLKHYWFTSWPDQKTPDRAP-PLLHLVREVEEAAQQEGPHCAPIIV 462
+ T++ ++H+ WP+ P + L+++++ EEA ++G P IV
Sbjct: 1296 HDFILEATQDDYVLEVRHFQCPKWPNPDAPISSTFELINVIK--EEALTRDG----PTIV 1349
Query: 463 HCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVM 520
H G G A + QQL E VD+ + + R G+ EQYQF++ M
Sbjct: 1350 HDEYGAVSAGMLCALTTLSQQLENENAVDVFQVAKMINLMRPGVFTDIEQYQFIYKAM 1407
>gi|18104993 protein tyrosine phosphatase, non-receptor type 6
isoform 3 [Homo sapiens]
Length = 624
Score = 175 bits (443), Expect = 1e-43
Identities = 102/238 (42%), Positives = 138/238 (57%), Gaps = 14/238 (5%)
Query: 293 KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGY--GGEE--KVYIATQGPIVSTV 348
KNRYK ILP HSRV L D + P S YINANYI+ G +E K YIA+QG + +TV
Sbjct: 273 KNRYKNILPFDHSRVILQGRDSNIPGSDYINANYIKNQLLGPDENAKTYIASQGCLEATV 332
Query: 349 ADFWRMVWQEHTPIIVMIT-NIEEMNEKCTEYWPE--EQVAYDGVEITVQKVIHTEDYRL 405
DFW+M WQE++ +IVM T +E+ KC YWPE Q AY +T T +Y+L
Sbjct: 333 NDFWQMAWQENSRVIVMTTREVEKGRNKCVPYWPEVGMQRAYGPYSVTNCGEHDTTEYKL 392
Query: 406 RLIS---LKSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIV 462
R + L +G R + HY + SWPD P +L + ++ + Q+ PH PIIV
Sbjct: 393 RTLQVSPLDNGDLIREIWHYQYLSWPDHGVPSEPGGVLSFLDQINQ-RQESLPHAGPIIV 451
Query: 463 HCSAGIGRTGCFIATSICCQQLRQEGV---VDILKTTCQLRQDRGGMIQTCEQYQFVH 517
HCSAGIGRTG I + + + +G+ +DI KT +R R GM+QT QY+F++
Sbjct: 452 HCSAGIGRTGTIIVIDMLMENISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFIY 509
>gi|18104989 protein tyrosine phosphatase, non-receptor type 6
isoform 1 [Homo sapiens]
Length = 595
Score = 175 bits (443), Expect = 1e-43
Identities = 102/238 (42%), Positives = 138/238 (57%), Gaps = 14/238 (5%)
Query: 293 KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGY--GGEE--KVYIATQGPIVSTV 348
KNRYK ILP HSRV L D + P S YINANYI+ G +E K YIA+QG + +TV
Sbjct: 273 KNRYKNILPFDHSRVILQGRDSNIPGSDYINANYIKNQLLGPDENAKTYIASQGCLEATV 332
Query: 349 ADFWRMVWQEHTPIIVMIT-NIEEMNEKCTEYWPE--EQVAYDGVEITVQKVIHTEDYRL 405
DFW+M WQE++ +IVM T +E+ KC YWPE Q AY +T T +Y+L
Sbjct: 333 NDFWQMAWQENSRVIVMTTREVEKGRNKCVPYWPEVGMQRAYGPYSVTNCGEHDTTEYKL 392
Query: 406 RLIS---LKSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIV 462
R + L +G R + HY + SWPD P +L + ++ + Q+ PH PIIV
Sbjct: 393 RTLQVSPLDNGDLIREIWHYQYLSWPDHGVPSEPGGVLSFLDQINQ-RQESLPHAGPIIV 451
Query: 463 HCSAGIGRTGCFIATSICCQQLRQEGV---VDILKTTCQLRQDRGGMIQTCEQYQFVH 517
HCSAGIGRTG I + + + +G+ +DI KT +R R GM+QT QY+F++
Sbjct: 452 HCSAGIGRTGTIIVIDMLMENISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFIY 509
>gi|18104991 protein tyrosine phosphatase, non-receptor type 6
isoform 2 [Homo sapiens]
Length = 597
Score = 175 bits (443), Expect = 1e-43
Identities = 102/238 (42%), Positives = 138/238 (57%), Gaps = 14/238 (5%)
Query: 293 KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGY--GGEE--KVYIATQGPIVSTV 348
KNRYK ILP HSRV L D + P S YINANYI+ G +E K YIA+QG + +TV
Sbjct: 275 KNRYKNILPFDHSRVILQGRDSNIPGSDYINANYIKNQLLGPDENAKTYIASQGCLEATV 334
Query: 349 ADFWRMVWQEHTPIIVMIT-NIEEMNEKCTEYWPE--EQVAYDGVEITVQKVIHTEDYRL 405
DFW+M WQE++ +IVM T +E+ KC YWPE Q AY +T T +Y+L
Sbjct: 335 NDFWQMAWQENSRVIVMTTREVEKGRNKCVPYWPEVGMQRAYGPYSVTNCGEHDTTEYKL 394
Query: 406 RLIS---LKSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIV 462
R + L +G R + HY + SWPD P +L + ++ + Q+ PH PIIV
Sbjct: 395 RTLQVSPLDNGDLIREIWHYQYLSWPDHGVPSEPGGVLSFLDQINQ-RQESLPHAGPIIV 453
Query: 463 HCSAGIGRTGCFIATSICCQQLRQEGV---VDILKTTCQLRQDRGGMIQTCEQYQFVH 517
HCSAGIGRTG I + + + +G+ +DI KT +R R GM+QT QY+F++
Sbjct: 454 HCSAGIGRTGTIIVIDMLMENISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFIY 511
>gi|33356177 protein tyrosine phosphatase, non-receptor type 11
[Homo sapiens]
Length = 593
Score = 174 bits (441), Expect = 2e-43
Identities = 103/257 (40%), Positives = 140/257 (54%), Gaps = 17/257 (6%)
Query: 293 KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIR-------GYGGEEKVYIATQGPIV 345
KNRYK ILP H+RV L DP++P+S YINAN I +K YIATQG +
Sbjct: 276 KNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQ 335
Query: 346 STVADFWRMVWQEHTPIIVMIT-NIEEMNEKCTEYWPEEQV--AYDGVEITVQKVIHTED 402
+TV DFWRMV+QE++ +IVM T +E KC +YWP+E Y + + K D
Sbjct: 336 NTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHD 395
Query: 403 YRLRLISLK---SGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAP 459
Y LR + L G ER + Y F +WPD P +L + EV Q+ P
Sbjct: 396 YTLRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHH-KQESIMDAGP 454
Query: 460 IIVHCSAGIGRTGCFIATSICCQQLRQEGV---VDILKTTCQLRQDRGGMIQTCEQYQFV 516
++VHCSAGIGRTG FI I +R++GV +D+ KT +R R GM+QT QY+F+
Sbjct: 455 VVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFI 514
Query: 517 HHVMSLYEKQLSHQSPE 533
+ + Y + L + E
Sbjct: 515 YMAVQHYIETLQRRIEE 531
>gi|104487611 protein tyrosine phosphatase, receptor type, sigma
isoform 4 precursor [Homo sapiens]
Length = 1505
Score = 174 bits (440), Expect = 2e-43
Identities = 93/232 (40%), Positives = 133/232 (57%), Gaps = 9/232 (3%)
Query: 293 KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFW 352
KNRY ++ HSRV L P S YINANY+ GY + YIATQGP+ T DFW
Sbjct: 976 KNRYANVIAYDHSRVIL-QPIEGIMGSDYINANYVDGYRCQN-AYIATQGPLPETFGDFW 1033
Query: 353 RMVWQEHTPIIVMITNIEEMNE-KCTEYWPEEQV-AYDGVEITVQKVIHTEDYRLRLISL 410
RMVW++ + IVM+T +EE + KC +YWP Y +++T+ I + +R SL
Sbjct: 1034 RMVWEQRSATIVMMTRLEEKSRIKCDQYWPNRGTETYGFIQVTLLDTIELATFCVRTFSL 1093
Query: 411 -KSGT-EERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGI 468
K+G+ E+R ++ + FT+WPD P+ P L +R V+ P PI+VHCSAG+
Sbjct: 1094 HKNGSSEKREVRQFQFTAWPDHGVPEYPTPFLAFLRRVKTC---NPPDAGPIVVHCSAGV 1150
Query: 469 GRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVM 520
GRTGCFI ++++ E VD+ +R R M+QT +QY F+H +
Sbjct: 1151 GRTGCFIVIDAMLERIKPEKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEAL 1202
Score = 172 bits (436), Expect = 7e-43
Identities = 96/241 (39%), Positives = 134/241 (55%), Gaps = 7/241 (2%)
Query: 293 KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFW 352
KNR I+P +RVCL P S YINA++I GY ++K YIATQGP+ T DFW
Sbjct: 1265 KNRLVNIMPYESTRVCL-QPIRGVEGSDYINASFIDGYR-QQKAYIATQGPLAETTEDFW 1322
Query: 353 RMVWQEHTPIIVMITNIEEMN-EKCTEYWPEEQVA-YDGVEITVQKVIHTEDYRLRLISL 410
RM+W+ ++ I+VM+T + EM EKC +YWP E+ A Y + + Y LR +
Sbjct: 1323 RMLWENNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKV 1382
Query: 411 KSGTE--ERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGI 468
+ R ++ + FT WP+Q P + + +V + +Q G PI VHCSAG+
Sbjct: 1383 TDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQD-GPISVHCSAGV 1441
Query: 469 GRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVMSLYEKQLS 528
GRTG FI SI +++R EGVVDI +T LR R M+QT ++YQF + Y
Sbjct: 1442 GRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDEYQFCYQAALEYLGSFD 1501
Query: 529 H 529
H
Sbjct: 1502 H 1502
>gi|104487297 protein tyrosine phosphatase, receptor type, sigma
isoform 2 precursor [Homo sapiens]
Length = 1910
Score = 174 bits (440), Expect = 2e-43
Identities = 93/232 (40%), Positives = 133/232 (57%), Gaps = 9/232 (3%)
Query: 293 KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFW 352
KNRY ++ HSRV L P S YINANY+ GY + YIATQGP+ T DFW
Sbjct: 1381 KNRYANVIAYDHSRVIL-QPIEGIMGSDYINANYVDGYRCQN-AYIATQGPLPETFGDFW 1438
Query: 353 RMVWQEHTPIIVMITNIEEMNE-KCTEYWPEEQV-AYDGVEITVQKVIHTEDYRLRLISL 410
RMVW++ + IVM+T +EE + KC +YWP Y +++T+ I + +R SL
Sbjct: 1439 RMVWEQRSATIVMMTRLEEKSRIKCDQYWPNRGTETYGFIQVTLLDTIELATFCVRTFSL 1498
Query: 411 -KSGT-EERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGI 468
K+G+ E+R ++ + FT+WPD P+ P L +R V+ P PI+VHCSAG+
Sbjct: 1499 HKNGSSEKREVRQFQFTAWPDHGVPEYPTPFLAFLRRVKTC---NPPDAGPIVVHCSAGV 1555
Query: 469 GRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVM 520
GRTGCFI ++++ E VD+ +R R M+QT +QY F+H +
Sbjct: 1556 GRTGCFIVIDAMLERIKPEKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEAL 1607
Score = 172 bits (436), Expect = 7e-43
Identities = 96/241 (39%), Positives = 134/241 (55%), Gaps = 7/241 (2%)
Query: 293 KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFW 352
KNR I+P +RVCL P S YINA++I GY ++K YIATQGP+ T DFW
Sbjct: 1670 KNRLVNIMPYESTRVCL-QPIRGVEGSDYINASFIDGYR-QQKAYIATQGPLAETTEDFW 1727
Query: 353 RMVWQEHTPIIVMITNIEEMN-EKCTEYWPEEQVA-YDGVEITVQKVIHTEDYRLRLISL 410
RM+W+ ++ I+VM+T + EM EKC +YWP E+ A Y + + Y LR +
Sbjct: 1728 RMLWENNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKV 1787
Query: 411 KSGTE--ERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGI 468
+ R ++ + FT WP+Q P + + +V + +Q G PI VHCSAG+
Sbjct: 1788 TDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQD-GPISVHCSAGV 1846
Query: 469 GRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVMSLYEKQLS 528
GRTG FI SI +++R EGVVDI +T LR R M+QT ++YQF + Y
Sbjct: 1847 GRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDEYQFCYQAALEYLGSFD 1906
Query: 529 H 529
H
Sbjct: 1907 H 1907
>gi|104487295 protein tyrosine phosphatase, receptor type, sigma
isoform 3 precursor [Homo sapiens]
Length = 1501
Score = 174 bits (440), Expect = 2e-43
Identities = 93/232 (40%), Positives = 133/232 (57%), Gaps = 9/232 (3%)
Query: 293 KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFW 352
KNRY ++ HSRV L P S YINANY+ GY + YIATQGP+ T DFW
Sbjct: 972 KNRYANVIAYDHSRVIL-QPIEGIMGSDYINANYVDGYRCQN-AYIATQGPLPETFGDFW 1029
Query: 353 RMVWQEHTPIIVMITNIEEMNE-KCTEYWPEEQV-AYDGVEITVQKVIHTEDYRLRLISL 410
RMVW++ + IVM+T +EE + KC +YWP Y +++T+ I + +R SL
Sbjct: 1030 RMVWEQRSATIVMMTRLEEKSRIKCDQYWPNRGTETYGFIQVTLLDTIELATFCVRTFSL 1089
Query: 411 -KSGT-EERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGI 468
K+G+ E+R ++ + FT+WPD P+ P L +R V+ P PI+VHCSAG+
Sbjct: 1090 HKNGSSEKREVRQFQFTAWPDHGVPEYPTPFLAFLRRVKTC---NPPDAGPIVVHCSAGV 1146
Query: 469 GRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVM 520
GRTGCFI ++++ E VD+ +R R M+QT +QY F+H +
Sbjct: 1147 GRTGCFIVIDAMLERIKPEKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEAL 1198
Score = 172 bits (436), Expect = 7e-43
Identities = 96/241 (39%), Positives = 134/241 (55%), Gaps = 7/241 (2%)
Query: 293 KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFW 352
KNR I+P +RVCL P S YINA++I GY ++K YIATQGP+ T DFW
Sbjct: 1261 KNRLVNIMPYESTRVCL-QPIRGVEGSDYINASFIDGYR-QQKAYIATQGPLAETTEDFW 1318
Query: 353 RMVWQEHTPIIVMITNIEEMN-EKCTEYWPEEQVA-YDGVEITVQKVIHTEDYRLRLISL 410
RM+W+ ++ I+VM+T + EM EKC +YWP E+ A Y + + Y LR +
Sbjct: 1319 RMLWENNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKV 1378
Query: 411 KSGTE--ERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGI 468
+ R ++ + FT WP+Q P + + +V + +Q G PI VHCSAG+
Sbjct: 1379 TDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQD-GPISVHCSAGV 1437
Query: 469 GRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVMSLYEKQLS 528
GRTG FI SI +++R EGVVDI +T LR R M+QT ++YQF + Y
Sbjct: 1438 GRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDEYQFCYQAALEYLGSFD 1497
Query: 529 H 529
H
Sbjct: 1498 H 1498
>gi|104487006 protein tyrosine phosphatase, receptor type, sigma
isoform 1 precursor [Homo sapiens]
Length = 1948
Score = 174 bits (440), Expect = 2e-43
Identities = 93/232 (40%), Positives = 133/232 (57%), Gaps = 9/232 (3%)
Query: 293 KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFW 352
KNRY ++ HSRV L P S YINANY+ GY + YIATQGP+ T DFW
Sbjct: 1419 KNRYANVIAYDHSRVIL-QPIEGIMGSDYINANYVDGYRCQN-AYIATQGPLPETFGDFW 1476
Query: 353 RMVWQEHTPIIVMITNIEEMNE-KCTEYWPEEQV-AYDGVEITVQKVIHTEDYRLRLISL 410
RMVW++ + IVM+T +EE + KC +YWP Y +++T+ I + +R SL
Sbjct: 1477 RMVWEQRSATIVMMTRLEEKSRIKCDQYWPNRGTETYGFIQVTLLDTIELATFCVRTFSL 1536
Query: 411 -KSGT-EERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGI 468
K+G+ E+R ++ + FT+WPD P+ P L +R V+ P PI+VHCSAG+
Sbjct: 1537 HKNGSSEKREVRQFQFTAWPDHGVPEYPTPFLAFLRRVKTC---NPPDAGPIVVHCSAGV 1593
Query: 469 GRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVM 520
GRTGCFI ++++ E VD+ +R R M+QT +QY F+H +
Sbjct: 1594 GRTGCFIVIDAMLERIKPEKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEAL 1645
Score = 172 bits (436), Expect = 7e-43
Identities = 96/241 (39%), Positives = 134/241 (55%), Gaps = 7/241 (2%)
Query: 293 KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFW 352
KNR I+P +RVCL P S YINA++I GY ++K YIATQGP+ T DFW
Sbjct: 1708 KNRLVNIMPYESTRVCL-QPIRGVEGSDYINASFIDGYR-QQKAYIATQGPLAETTEDFW 1765
Query: 353 RMVWQEHTPIIVMITNIEEMN-EKCTEYWPEEQVA-YDGVEITVQKVIHTEDYRLRLISL 410
RM+W+ ++ I+VM+T + EM EKC +YWP E+ A Y + + Y LR +
Sbjct: 1766 RMLWENNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKV 1825
Query: 411 KSGTE--ERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGI 468
+ R ++ + FT WP+Q P + + +V + +Q G PI VHCSAG+
Sbjct: 1826 TDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQD-GPISVHCSAGV 1884
Query: 469 GRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVMSLYEKQLS 528
GRTG FI SI +++R EGVVDI +T LR R M+QT ++YQF + Y
Sbjct: 1885 GRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDEYQFCYQAALEYLGSFD 1944
Query: 529 H 529
H
Sbjct: 1945 H 1945
>gi|104487002 protein tyrosine phosphatase, receptor type, D isoform 5
precursor [Homo sapiens]
Length = 1502
Score = 173 bits (438), Expect = 4e-43
Identities = 97/241 (40%), Positives = 134/241 (55%), Gaps = 7/241 (2%)
Query: 293 KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFW 352
KNR I+P +RVCL P S YINA++I GY ++K YIATQGP+ T DFW
Sbjct: 1262 KNRLVNIMPYESTRVCL-QPIRGVEGSDYINASFIDGYR-QQKAYIATQGPLAETTEDFW 1319
Query: 353 RMVWQEHTPIIVMITNIEEMN-EKCTEYWPEEQVA-YDGVEITVQKVIHTEDYRLRLISL 410
RM+W+ ++ I+VM+T + EM EKC +YWP E+ A Y + + Y LR +
Sbjct: 1320 RMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKV 1379
Query: 411 KSGTE--ERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGI 468
+ R ++ + FT WP+Q P + + +V + +Q G PI VHCSAG+
Sbjct: 1380 TDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQD-GPISVHCSAGV 1438
Query: 469 GRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVMSLYEKQLS 528
GRTG FI SI +++R EGVVDI +T LR R M+QT +QYQF + Y
Sbjct: 1439 GRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFSYRAALEYLGSFD 1498
Query: 529 H 529
H
Sbjct: 1499 H 1499
Score = 172 bits (437), Expect = 5e-43
Identities = 90/232 (38%), Positives = 136/232 (58%), Gaps = 9/232 (3%)
Query: 293 KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFW 352
KNRY ++ HSRV L++ + P S Y+NANYI GY ++ YIATQG + T DFW
Sbjct: 973 KNRYANVIAYDHSRVLLSAIE-GIPGSDYVNANYIDGYR-KQNAYIATQGSLPETFGDFW 1030
Query: 353 RMVWQEHTPIIVMITNIEEMNE-KCTEYWPEEQVAYDG-VEITVQKVIHTEDYRLRLISL 410
RM+W++ + +VM+T +EE + KC +YWP G V++T+ + Y +R +L
Sbjct: 1031 RMIWEQRSATVVMMTKLEERSRVKCDQYWPSRGTETHGLVQVTLLDTVELATYCVRTFAL 1090
Query: 411 -KSGT-EERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGI 468
K+G+ E+R ++ + FT+WPD P+ P L +R V+ P P++VHCSAG+
Sbjct: 1091 YKNGSSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKTC---NPPDAGPMVVHCSAGV 1147
Query: 469 GRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVM 520
GRTGCFI ++++ E VDI +R R M+QT +QY F+H +
Sbjct: 1148 GRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDAL 1199
>gi|4506309 protein tyrosine phosphatase, receptor type, D isoform 1
precursor [Homo sapiens]
Length = 1912
Score = 173 bits (438), Expect = 4e-43
Identities = 97/241 (40%), Positives = 134/241 (55%), Gaps = 7/241 (2%)
Query: 293 KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFW 352
KNR I+P +RVCL P S YINA++I GY ++K YIATQGP+ T DFW
Sbjct: 1672 KNRLVNIMPYESTRVCL-QPIRGVEGSDYINASFIDGYR-QQKAYIATQGPLAETTEDFW 1729
Query: 353 RMVWQEHTPIIVMITNIEEMN-EKCTEYWPEEQVA-YDGVEITVQKVIHTEDYRLRLISL 410
RM+W+ ++ I+VM+T + EM EKC +YWP E+ A Y + + Y LR +
Sbjct: 1730 RMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKV 1789
Query: 411 KSGTE--ERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGI 468
+ R ++ + FT WP+Q P + + +V + +Q G PI VHCSAG+
Sbjct: 1790 TDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQD-GPISVHCSAGV 1848
Query: 469 GRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVMSLYEKQLS 528
GRTG FI SI +++R EGVVDI +T LR R M+QT +QYQF + Y
Sbjct: 1849 GRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFSYRAALEYLGSFD 1908
Query: 529 H 529
H
Sbjct: 1909 H 1909
Score = 172 bits (437), Expect = 5e-43
Identities = 90/232 (38%), Positives = 136/232 (58%), Gaps = 9/232 (3%)
Query: 293 KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFW 352
KNRY ++ HSRV L++ + P S Y+NANYI GY ++ YIATQG + T DFW
Sbjct: 1383 KNRYANVIAYDHSRVLLSAIE-GIPGSDYVNANYIDGYR-KQNAYIATQGSLPETFGDFW 1440
Query: 353 RMVWQEHTPIIVMITNIEEMNE-KCTEYWPEEQVAYDG-VEITVQKVIHTEDYRLRLISL 410
RM+W++ + +VM+T +EE + KC +YWP G V++T+ + Y +R +L
Sbjct: 1441 RMIWEQRSATVVMMTKLEERSRVKCDQYWPSRGTETHGLVQVTLLDTVELATYCVRTFAL 1500
Query: 411 -KSGT-EERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGI 468
K+G+ E+R ++ + FT+WPD P+ P L +R V+ P P++VHCSAG+
Sbjct: 1501 YKNGSSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKTC---NPPDAGPMVVHCSAGV 1557
Query: 469 GRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVM 520
GRTGCFI ++++ E VDI +R R M+QT +QY F+H +
Sbjct: 1558 GRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDAL 1609
>gi|18860890 protein tyrosine phosphatase, receptor type, D isoform 2
precursor [Homo sapiens]
Length = 1899
Score = 173 bits (438), Expect = 4e-43
Identities = 97/241 (40%), Positives = 134/241 (55%), Gaps = 7/241 (2%)
Query: 293 KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFW 352
KNR I+P +RVCL P S YINA++I GY ++K YIATQGP+ T DFW
Sbjct: 1659 KNRLVNIMPYESTRVCL-QPIRGVEGSDYINASFIDGYR-QQKAYIATQGPLAETTEDFW 1716
Query: 353 RMVWQEHTPIIVMITNIEEMN-EKCTEYWPEEQVA-YDGVEITVQKVIHTEDYRLRLISL 410
RM+W+ ++ I+VM+T + EM EKC +YWP E+ A Y + + Y LR +
Sbjct: 1717 RMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKV 1776
Query: 411 KSGTE--ERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGI 468
+ R ++ + FT WP+Q P + + +V + +Q G PI VHCSAG+
Sbjct: 1777 TDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQD-GPISVHCSAGV 1835
Query: 469 GRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVMSLYEKQLS 528
GRTG FI SI +++R EGVVDI +T LR R M+QT +QYQF + Y
Sbjct: 1836 GRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFSYRAALEYLGSFD 1895
Query: 529 H 529
H
Sbjct: 1896 H 1896
Score = 172 bits (437), Expect = 5e-43
Identities = 90/232 (38%), Positives = 136/232 (58%), Gaps = 9/232 (3%)
Query: 293 KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFW 352
KNRY ++ HSRV L++ + P S Y+NANYI GY ++ YIATQG + T DFW
Sbjct: 1370 KNRYANVIAYDHSRVLLSAIE-GIPGSDYVNANYIDGYR-KQNAYIATQGSLPETFGDFW 1427
Query: 353 RMVWQEHTPIIVMITNIEEMNE-KCTEYWPEEQVAYDG-VEITVQKVIHTEDYRLRLISL 410
RM+W++ + +VM+T +EE + KC +YWP G V++T+ + Y +R +L
Sbjct: 1428 RMIWEQRSATVVMMTKLEERSRVKCDQYWPSRGTETHGLVQVTLLDTVELATYCVRTFAL 1487
Query: 411 -KSGT-EERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGI 468
K+G+ E+R ++ + FT+WPD P+ P L +R V+ P P++VHCSAG+
Sbjct: 1488 YKNGSSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKTC---NPPDAGPMVVHCSAGV 1544
Query: 469 GRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVM 520
GRTGCFI ++++ E VDI +R R M+QT +QY F+H +
Sbjct: 1545 GRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDAL 1596
>gi|18860892 protein tyrosine phosphatase, receptor type, D isoform 3
precursor [Homo sapiens]
Length = 1903
Score = 173 bits (438), Expect = 4e-43
Identities = 97/241 (40%), Positives = 134/241 (55%), Gaps = 7/241 (2%)
Query: 293 KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFW 352
KNR I+P +RVCL P S YINA++I GY ++K YIATQGP+ T DFW
Sbjct: 1663 KNRLVNIMPYESTRVCL-QPIRGVEGSDYINASFIDGYR-QQKAYIATQGPLAETTEDFW 1720
Query: 353 RMVWQEHTPIIVMITNIEEMN-EKCTEYWPEEQVA-YDGVEITVQKVIHTEDYRLRLISL 410
RM+W+ ++ I+VM+T + EM EKC +YWP E+ A Y + + Y LR +
Sbjct: 1721 RMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKV 1780
Query: 411 KSGTE--ERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGI 468
+ R ++ + FT WP+Q P + + +V + +Q G PI VHCSAG+
Sbjct: 1781 TDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQD-GPISVHCSAGV 1839
Query: 469 GRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVMSLYEKQLS 528
GRTG FI SI +++R EGVVDI +T LR R M+QT +QYQF + Y
Sbjct: 1840 GRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFSYRAALEYLGSFD 1899
Query: 529 H 529
H
Sbjct: 1900 H 1900
Score = 172 bits (437), Expect = 5e-43
Identities = 90/232 (38%), Positives = 136/232 (58%), Gaps = 9/232 (3%)
Query: 293 KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFW 352
KNRY ++ HSRV L++ + P S Y+NANYI GY ++ YIATQG + T DFW
Sbjct: 1374 KNRYANVIAYDHSRVLLSAIE-GIPGSDYVNANYIDGYR-KQNAYIATQGSLPETFGDFW 1431
Query: 353 RMVWQEHTPIIVMITNIEEMNE-KCTEYWPEEQVAYDG-VEITVQKVIHTEDYRLRLISL 410
RM+W++ + +VM+T +EE + KC +YWP G V++T+ + Y +R +L
Sbjct: 1432 RMIWEQRSATVVMMTKLEERSRVKCDQYWPSRGTETHGLVQVTLLDTVELATYCVRTFAL 1491
Query: 411 -KSGT-EERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGI 468
K+G+ E+R ++ + FT+WPD P+ P L +R V+ P P++VHCSAG+
Sbjct: 1492 YKNGSSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKTC---NPPDAGPMVVHCSAGV 1548
Query: 469 GRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVM 520
GRTGCFI ++++ E VDI +R R M+QT +QY F+H +
Sbjct: 1549 GRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDAL 1600
>gi|18860894 protein tyrosine phosphatase, receptor type, D isoform 4
precursor [Homo sapiens]
Length = 1501
Score = 173 bits (438), Expect = 4e-43
Identities = 97/241 (40%), Positives = 134/241 (55%), Gaps = 7/241 (2%)
Query: 293 KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFW 352
KNR I+P +RVCL P S YINA++I GY ++K YIATQGP+ T DFW
Sbjct: 1261 KNRLVNIMPYESTRVCL-QPIRGVEGSDYINASFIDGYR-QQKAYIATQGPLAETTEDFW 1318
Query: 353 RMVWQEHTPIIVMITNIEEMN-EKCTEYWPEEQVA-YDGVEITVQKVIHTEDYRLRLISL 410
RM+W+ ++ I+VM+T + EM EKC +YWP E+ A Y + + Y LR +
Sbjct: 1319 RMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKV 1378
Query: 411 KSGTE--ERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGI 468
+ R ++ + FT WP+Q P + + +V + +Q G PI VHCSAG+
Sbjct: 1379 TDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQD-GPISVHCSAGV 1437
Query: 469 GRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVMSLYEKQLS 528
GRTG FI SI +++R EGVVDI +T LR R M+QT +QYQF + Y
Sbjct: 1438 GRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFSYRAALEYLGSFD 1497
Query: 529 H 529
H
Sbjct: 1498 H 1498
Score = 172 bits (437), Expect = 5e-43
Identities = 90/232 (38%), Positives = 136/232 (58%), Gaps = 9/232 (3%)
Query: 293 KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFW 352
KNRY ++ HSRV L++ + P S Y+NANYI GY ++ YIATQG + T DFW
Sbjct: 972 KNRYANVIAYDHSRVLLSAIE-GIPGSDYVNANYIDGYR-KQNAYIATQGSLPETFGDFW 1029
Query: 353 RMVWQEHTPIIVMITNIEEMNE-KCTEYWPEEQVAYDG-VEITVQKVIHTEDYRLRLISL 410
RM+W++ + +VM+T +EE + KC +YWP G V++T+ + Y +R +L
Sbjct: 1030 RMIWEQRSATVVMMTKLEERSRVKCDQYWPSRGTETHGLVQVTLLDTVELATYCVRTFAL 1089
Query: 411 -KSGT-EERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGI 468
K+G+ E+R ++ + FT+WPD P+ P L +R V+ P P++VHCSAG+
Sbjct: 1090 YKNGSSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKTC---NPPDAGPMVVHCSAGV 1146
Query: 469 GRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVM 520
GRTGCFI ++++ E VDI +R R M+QT +QY F+H +
Sbjct: 1147 GRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDAL 1198
>gi|91208428 protein tyrosine phosphatase, receptor-type, zeta1
precursor [Homo sapiens]
Length = 2315
Score = 171 bits (432), Expect = 2e-42
Identities = 95/246 (38%), Positives = 135/246 (54%), Gaps = 17/246 (6%)
Query: 288 PGLVRKNRYKTILPNPHSRVCLTS-PDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVS 346
P KNRY I+ HSRV L + D L+ YINANY+ GY K YIA QGP+ S
Sbjct: 1748 PDNKHKNRYINIVAYDHSRVKLAQLAEKDGKLTDYINANYVDGYN-RPKAYIAAQGPLKS 1806
Query: 347 TVADFWRMVWQEHTPIIVMITN-IEEMNEKCTEYWPEEQVAYDGVEITVQKVIHT----- 400
T DFWRM+W+ + +IVMITN +E+ KC +YWP + G + QK +
Sbjct: 1807 TAEDFWRMIWEHNVEVIVMITNLVEKGRRKCDQYWPADGSEEYGNFLVTQKSVQVLAYYT 1866
Query: 401 -EDYRLRLISLKSGTEE-----RGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEG 454
++ LR +K G+++ R + Y +T WPD P+ + P+L VR+ AA +
Sbjct: 1867 VRNFTLRNTKIKKGSQKGRPSGRVVTQYHYTQWPDMGVPEYSLPVLTFVRK---AAYAKR 1923
Query: 455 PHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQ 514
P++VHCSAG+GRTG +I QQ++ EG V+I +R R ++QT EQY
Sbjct: 1924 HAVGPVVVHCSAGVGRTGTYIVLDSMLQQIQHEGTVNIFGFLKHIRSQRNYLVQTEEQYV 1983
Query: 515 FVHHVM 520
F+H +
Sbjct: 1984 FIHDTL 1989
Score = 108 bits (270), Expect = 1e-23
Identities = 72/238 (30%), Positives = 124/238 (52%), Gaps = 19/238 (7%)
Query: 293 KNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFW 352
KNR +I+P SRV ++S + + YINA+YI GY + +I TQ P++ T+ DFW
Sbjct: 2051 KNRTSSIIPVERSRVGISSLSGEG--TDYINASYIMGYY-QSNEFIITQHPLLHTIKDFW 2107
Query: 353 RMVWQEHTPIIVMITNIEEMNEKCTEYWP--EEQVAYDGVEITV----QKVIHTEDYRLR 406
RM+W + ++VMI + + M E YWP +E + + ++T+ K + E+ +
Sbjct: 2108 RMIWDHNAQLVVMIPDGQNMAEDEFVYWPNKDEPINCESFKVTLMAEEHKCLSNEEKLII 2167
Query: 407 LISLKSGTEE---RGLKHYWFTSWPDQKTP-DRAPPLLHLVREVEEAAQQEGPHCAPIIV 462
+ T++ ++H+ WP+ +P + L+ +++ EEAA ++G P+IV
Sbjct: 2168 QDFILEATQDDYVLEVRHFQCPKWPNPDSPISKTFELISVIK--EEAANRDG----PMIV 2221
Query: 463 HCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVM 520
H G G F A + QL +E VD+ + + R G+ EQYQF++ V+
Sbjct: 2222 HDEHGGVTAGTFCALTTLMHQLEKENSVDVYQVAKMINLMRPGVFADIEQYQFLYKVI 2279
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.135 0.420
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,891,909
Number of Sequences: 37866
Number of extensions: 1489091
Number of successful extensions: 23950
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 414
Number of HSP's successfully gapped in prelim test: 249
Number of HSP's that attempted gapping in prelim test: 14845
Number of HSP's gapped (non-prelim): 6216
length of query: 533
length of database: 18,247,518
effective HSP length: 107
effective length of query: 426
effective length of database: 14,195,856
effective search space: 6047434656
effective search space used: 6047434656
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.