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Search of human proteins with 89353281
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|89353281 serologically defined colon cancer antigen 3
isoform 1 [Homo sapiens]
(435 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|89353281 serologically defined colon cancer antigen 3 isoform... 868 0.0
gi|89353278 serologically defined colon cancer antigen 3 isoform... 803 0.0
gi|89353283 serologically defined colon cancer antigen 3 isoform... 664 0.0
gi|51317384 GLE1 RNA export mediator homolog isoform 1 [Homo sap... 45 1e-04
gi|4557627 GLE1 RNA export mediator homolog isoform 2 [Homo sapi... 45 1e-04
gi|87298937 centrosomal protein 110kDa [Homo sapiens] 45 1e-04
gi|157388975 coiled-coil domain containing 99 [Homo sapiens] 45 1e-04
gi|118498356 kinectin 1 isoform a [Homo sapiens] 44 3e-04
gi|118498368 kinectin 1 isoform c [Homo sapiens] 44 3e-04
gi|33620775 kinectin 1 isoform a [Homo sapiens] 44 3e-04
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 44 4e-04
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 44 4e-04
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 44 4e-04
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 44 4e-04
gi|219689136 coiled-coil domain containing 68 [Homo sapiens] 43 5e-04
gi|13376818 coiled-coil domain containing 68 [Homo sapiens] 43 5e-04
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 42 8e-04
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 42 8e-04
gi|4503593 epidermal growth factor receptor pathway substrate 15... 42 0.001
gi|154354990 ankyrin repeat domain 26 [Homo sapiens] 42 0.001
gi|89357932 keratin 5b [Homo sapiens] 42 0.001
gi|7705415 hook homolog 1 [Homo sapiens] 42 0.001
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 41 0.002
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 41 0.002
gi|42794779 myosin 18A isoform b [Homo sapiens] 41 0.002
gi|23503243 Ras association (RalGDS/AF-6) domain family (N-termi... 41 0.002
gi|13540600 nudE nuclear distribution gene E homolog (A. nidulan... 41 0.002
gi|71284108 nudE nuclear distribution gene E homolog (A. nidulan... 41 0.002
gi|224586823 coiled-coil domain containing 110 isoform b [Homo s... 41 0.002
gi|22749515 coiled-coil domain containing 110 isoform a [Homo sa... 41 0.002
>gi|89353281 serologically defined colon cancer antigen 3 isoform 1
[Homo sapiens]
Length = 435
Score = 868 bits (2243), Expect = 0.0
Identities = 435/435 (100%), Positives = 435/435 (100%)
Query: 1 MSGYQRRPGATPLSRARSLAIPDAPAFYERRSCLPQLNCERPHGRDLDSPFFGIRPAFMC 60
MSGYQRRPGATPLSRARSLAIPDAPAFYERRSCLPQLNCERPHGRDLDSPFFGIRPAFMC
Sbjct: 1 MSGYQRRPGATPLSRARSLAIPDAPAFYERRSCLPQLNCERPHGRDLDSPFFGIRPAFMC 60
Query: 61 YVPSPVLASVGDTDFGYGKGKCSKQSPSGAHGTHFGDDRFEDLEEANPFSFREFLKTKNL 120
YVPSPVLASVGDTDFGYGKGKCSKQSPSGAHGTHFGDDRFEDLEEANPFSFREFLKTKNL
Sbjct: 61 YVPSPVLASVGDTDFGYGKGKCSKQSPSGAHGTHFGDDRFEDLEEANPFSFREFLKTKNL 120
Query: 121 GLSKEDPASRIYAKEASRHSLGLDHNSPPSQTGGYGLEYQQPFFEDPTGAGDLLDEEEDE 180
GLSKEDPASRIYAKEASRHSLGLDHNSPPSQTGGYGLEYQQPFFEDPTGAGDLLDEEEDE
Sbjct: 121 GLSKEDPASRIYAKEASRHSLGLDHNSPPSQTGGYGLEYQQPFFEDPTGAGDLLDEEEDE 180
Query: 181 DTGWSGAYLPSAIEQTHPERVPAGTSPCSTYLSFFSTPSELAGPESLPSWALSDTDSRVS 240
DTGWSGAYLPSAIEQTHPERVPAGTSPCSTYLSFFSTPSELAGPESLPSWALSDTDSRVS
Sbjct: 181 DTGWSGAYLPSAIEQTHPERVPAGTSPCSTYLSFFSTPSELAGPESLPSWALSDTDSRVS 240
Query: 241 PASPAGSPSADFAVHGESLGDRHLRTLQISYDALKDENSKLRRKLNEVQSFSEAQTEMVR 300
PASPAGSPSADFAVHGESLGDRHLRTLQISYDALKDENSKLRRKLNEVQSFSEAQTEMVR
Sbjct: 241 PASPAGSPSADFAVHGESLGDRHLRTLQISYDALKDENSKLRRKLNEVQSFSEAQTEMVR 300
Query: 301 TLERKLEAKMIKEESDYHDLESVVQQVEQNLELMTKRAVKAENHVVKLKQEISLLQAQVS 360
TLERKLEAKMIKEESDYHDLESVVQQVEQNLELMTKRAVKAENHVVKLKQEISLLQAQVS
Sbjct: 301 TLERKLEAKMIKEESDYHDLESVVQQVEQNLELMTKRAVKAENHVVKLKQEISLLQAQVS 360
Query: 361 NFQRENEALRCGQGASLTVVKQNADVALQNLRVVMNSAQASIKQLVSGAETLNLVAEILK 420
NFQRENEALRCGQGASLTVVKQNADVALQNLRVVMNSAQASIKQLVSGAETLNLVAEILK
Sbjct: 361 NFQRENEALRCGQGASLTVVKQNADVALQNLRVVMNSAQASIKQLVSGAETLNLVAEILK 420
Query: 421 SIDRISEVKDEEEDS 435
SIDRISEVKDEEEDS
Sbjct: 421 SIDRISEVKDEEEDS 435
>gi|89353278 serologically defined colon cancer antigen 3 isoform 2
[Homo sapiens]
Length = 412
Score = 803 bits (2075), Expect = 0.0
Identities = 412/435 (94%), Positives = 412/435 (94%), Gaps = 23/435 (5%)
Query: 1 MSGYQRRPGATPLSRARSLAIPDAPAFYERRSCLPQLNCERPHGRDLDSPFFGIRPAFMC 60
MSGYQRRPGATPLSRARSLAIPDAPAFYERRSCLPQLNCERPHGRDLDSPFFGIRPAFMC
Sbjct: 1 MSGYQRRPGATPLSRARSLAIPDAPAFYERRSCLPQLNCERPHGRDLDSPFFGIRPAFMC 60
Query: 61 YVPSPVLASVGDTDFGYGKGKCSKQSPSGAHGTHFGDDRFEDLEEANPFSFREFLKTKNL 120
YVPSPVLASVGDTD DRFEDLEEANPFSFREFLKTKNL
Sbjct: 61 YVPSPVLASVGDTD-----------------------DRFEDLEEANPFSFREFLKTKNL 97
Query: 121 GLSKEDPASRIYAKEASRHSLGLDHNSPPSQTGGYGLEYQQPFFEDPTGAGDLLDEEEDE 180
GLSKEDPASRIYAKEASRHSLGLDHNSPPSQTGGYGLEYQQPFFEDPTGAGDLLDEEEDE
Sbjct: 98 GLSKEDPASRIYAKEASRHSLGLDHNSPPSQTGGYGLEYQQPFFEDPTGAGDLLDEEEDE 157
Query: 181 DTGWSGAYLPSAIEQTHPERVPAGTSPCSTYLSFFSTPSELAGPESLPSWALSDTDSRVS 240
DTGWSGAYLPSAIEQTHPERVPAGTSPCSTYLSFFSTPSELAGPESLPSWALSDTDSRVS
Sbjct: 158 DTGWSGAYLPSAIEQTHPERVPAGTSPCSTYLSFFSTPSELAGPESLPSWALSDTDSRVS 217
Query: 241 PASPAGSPSADFAVHGESLGDRHLRTLQISYDALKDENSKLRRKLNEVQSFSEAQTEMVR 300
PASPAGSPSADFAVHGESLGDRHLRTLQISYDALKDENSKLRRKLNEVQSFSEAQTEMVR
Sbjct: 218 PASPAGSPSADFAVHGESLGDRHLRTLQISYDALKDENSKLRRKLNEVQSFSEAQTEMVR 277
Query: 301 TLERKLEAKMIKEESDYHDLESVVQQVEQNLELMTKRAVKAENHVVKLKQEISLLQAQVS 360
TLERKLEAKMIKEESDYHDLESVVQQVEQNLELMTKRAVKAENHVVKLKQEISLLQAQVS
Sbjct: 278 TLERKLEAKMIKEESDYHDLESVVQQVEQNLELMTKRAVKAENHVVKLKQEISLLQAQVS 337
Query: 361 NFQRENEALRCGQGASLTVVKQNADVALQNLRVVMNSAQASIKQLVSGAETLNLVAEILK 420
NFQRENEALRCGQGASLTVVKQNADVALQNLRVVMNSAQASIKQLVSGAETLNLVAEILK
Sbjct: 338 NFQRENEALRCGQGASLTVVKQNADVALQNLRVVMNSAQASIKQLVSGAETLNLVAEILK 397
Query: 421 SIDRISEVKDEEEDS 435
SIDRISEVKDEEEDS
Sbjct: 398 SIDRISEVKDEEEDS 412
>gi|89353283 serologically defined colon cancer antigen 3 isoform 3
[Homo sapiens]
Length = 362
Score = 664 bits (1714), Expect = 0.0
Identities = 339/339 (100%), Positives = 339/339 (100%)
Query: 97 DDRFEDLEEANPFSFREFLKTKNLGLSKEDPASRIYAKEASRHSLGLDHNSPPSQTGGYG 156
DDRFEDLEEANPFSFREFLKTKNLGLSKEDPASRIYAKEASRHSLGLDHNSPPSQTGGYG
Sbjct: 24 DDRFEDLEEANPFSFREFLKTKNLGLSKEDPASRIYAKEASRHSLGLDHNSPPSQTGGYG 83
Query: 157 LEYQQPFFEDPTGAGDLLDEEEDEDTGWSGAYLPSAIEQTHPERVPAGTSPCSTYLSFFS 216
LEYQQPFFEDPTGAGDLLDEEEDEDTGWSGAYLPSAIEQTHPERVPAGTSPCSTYLSFFS
Sbjct: 84 LEYQQPFFEDPTGAGDLLDEEEDEDTGWSGAYLPSAIEQTHPERVPAGTSPCSTYLSFFS 143
Query: 217 TPSELAGPESLPSWALSDTDSRVSPASPAGSPSADFAVHGESLGDRHLRTLQISYDALKD 276
TPSELAGPESLPSWALSDTDSRVSPASPAGSPSADFAVHGESLGDRHLRTLQISYDALKD
Sbjct: 144 TPSELAGPESLPSWALSDTDSRVSPASPAGSPSADFAVHGESLGDRHLRTLQISYDALKD 203
Query: 277 ENSKLRRKLNEVQSFSEAQTEMVRTLERKLEAKMIKEESDYHDLESVVQQVEQNLELMTK 336
ENSKLRRKLNEVQSFSEAQTEMVRTLERKLEAKMIKEESDYHDLESVVQQVEQNLELMTK
Sbjct: 204 ENSKLRRKLNEVQSFSEAQTEMVRTLERKLEAKMIKEESDYHDLESVVQQVEQNLELMTK 263
Query: 337 RAVKAENHVVKLKQEISLLQAQVSNFQRENEALRCGQGASLTVVKQNADVALQNLRVVMN 396
RAVKAENHVVKLKQEISLLQAQVSNFQRENEALRCGQGASLTVVKQNADVALQNLRVVMN
Sbjct: 264 RAVKAENHVVKLKQEISLLQAQVSNFQRENEALRCGQGASLTVVKQNADVALQNLRVVMN 323
Query: 397 SAQASIKQLVSGAETLNLVAEILKSIDRISEVKDEEEDS 435
SAQASIKQLVSGAETLNLVAEILKSIDRISEVKDEEEDS
Sbjct: 324 SAQASIKQLVSGAETLNLVAEILKSIDRISEVKDEEEDS 362
>gi|51317384 GLE1 RNA export mediator homolog isoform 1 [Homo
sapiens]
Length = 698
Score = 45.1 bits (105), Expect = 1e-04
Identities = 60/236 (25%), Positives = 105/236 (44%), Gaps = 34/236 (14%)
Query: 182 TGWSGAYLPSAIEQTHPERVPAGTSPCSTYLSFFSTPSELAGPESLPSWALSDTDSRVSP 241
+GW ++ +++ P + TSP ST S PS + P+S + S S SP
Sbjct: 49 SGWVVEHVLPHMQENQPL---SETSPSSTSASALDQPSFV--PKSPDA---SSAFSPASP 100
Query: 242 ASPAGSPSADFAVHGESLGDRHLRTLQIS-----YDALK----DENSKLRRKLNE--VQS 290
A+P G+ D + H ES+ + R +++ Y+ + E +L ++ E VQ+
Sbjct: 101 ATPNGTKGKDESQHTESMVLQSSRGIKVEGCVRMYELVHRMKGTEGLRLWQEEQERKVQA 160
Query: 291 FSEAQTEMVRTLERKLEAKMIKEESDYHDLESVVQQVEQNLELMTKRAVKAENHVVKLKQ 350
SE +E ++ + E K +K+ ++ DL E+M K + +A H KLK
Sbjct: 161 LSEMASEQLKRFD---EWKELKQHKEFQDLR----------EVMEKSSREALGHQEKLKA 207
Query: 351 EISLLQAQVSNFQ-RENEALRCGQGASLTVVKQNADVALQNLRVVMNSAQASIKQL 405
E +A++ N + RE E R Q + K+ + L+ L + +QL
Sbjct: 208 E-HRHRAKILNLKLREAEQQRVKQAEQERLRKEEGQIRLRALYALQEEMLQLSQQL 262
>gi|4557627 GLE1 RNA export mediator homolog isoform 2 [Homo
sapiens]
Length = 659
Score = 45.1 bits (105), Expect = 1e-04
Identities = 60/236 (25%), Positives = 105/236 (44%), Gaps = 34/236 (14%)
Query: 182 TGWSGAYLPSAIEQTHPERVPAGTSPCSTYLSFFSTPSELAGPESLPSWALSDTDSRVSP 241
+GW ++ +++ P + TSP ST S PS + P+S + S S SP
Sbjct: 49 SGWVVEHVLPHMQENQPL---SETSPSSTSASALDQPSFV--PKSPDA---SSAFSPASP 100
Query: 242 ASPAGSPSADFAVHGESLGDRHLRTLQIS-----YDALK----DENSKLRRKLNE--VQS 290
A+P G+ D + H ES+ + R +++ Y+ + E +L ++ E VQ+
Sbjct: 101 ATPNGTKGKDESQHTESMVLQSSRGIKVEGCVRMYELVHRMKGTEGLRLWQEEQERKVQA 160
Query: 291 FSEAQTEMVRTLERKLEAKMIKEESDYHDLESVVQQVEQNLELMTKRAVKAENHVVKLKQ 350
SE +E ++ + E K +K+ ++ DL E+M K + +A H KLK
Sbjct: 161 LSEMASEQLKRFD---EWKELKQHKEFQDLR----------EVMEKSSREALGHQEKLKA 207
Query: 351 EISLLQAQVSNFQ-RENEALRCGQGASLTVVKQNADVALQNLRVVMNSAQASIKQL 405
E +A++ N + RE E R Q + K+ + L+ L + +QL
Sbjct: 208 E-HRHRAKILNLKLREAEQQRVKQAEQERLRKEEGQIRLRALYALQEEMLQLSQQL 262
>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
Length = 2325
Score = 45.1 bits (105), Expect = 1e-04
Identities = 34/131 (25%), Positives = 67/131 (51%), Gaps = 3/131 (2%)
Query: 272 DALKDENSKLRRKLNEVQSFSEAQTEMVRTLERKL-EAKMIKEESDYHDLESVVQQVEQN 330
D + + +L +L+E+ S +TE ++ LE +L E ++ E+ DLE V+ +++
Sbjct: 565 DIMNKQYQQLESRLDEILSRIAKETEEIKDLEEQLTEGQIAANEALKKDLEGVISGLQEY 624
Query: 331 LELMTKRAVKAENHVVKLKQEISLLQAQVSNFQRENEALRCGQGASLTVVKQNADV--AL 388
L + +A +A+N KL+ E L +++ ++E + L + + K+ A++ AL
Sbjct: 625 LGTIKGQATQAQNECRKLRDEKETLLQRLTEVEQERDQLEIVAMDAENMRKELAELESAL 684
Query: 389 QNLRVVMNSAQ 399
Q V S Q
Sbjct: 685 QEQHEVNASLQ 695
Score = 35.4 bits (80), Expect = 0.10
Identities = 45/178 (25%), Positives = 85/178 (47%), Gaps = 21/178 (11%)
Query: 261 DRHLRTLQISYDALKDENSKLRRKLNEVQSFSEAQTEMVRTLERKLEAKMIKEESDYHDL 320
D HL+ L+ S L+ + ++L + ++V S Q + + L+R+L K KEE H L
Sbjct: 1562 DHHLQVLKESEVLLQAKRAELEKLKSQVTS----QQQEMAVLDRQLGHK--KEE--LHLL 1613
Query: 321 E-SVVQ---QVEQNLELMTKRAVKAENHVVKLKQEISLLQAQVSNFQRENEALRCGQGAS 376
+ S+VQ +++ L L + NH+ +E+ L ++S + E +
Sbjct: 1614 QGSMVQAKADLQEALRLGETEVTEKCNHI----REVKSLLEELSFQKGELNVQISERKTQ 1669
Query: 377 LTVVKQNADVALQNLRVVMNSAQASIKQLVSGAETLNLVAEILKSI-----DRISEVK 429
LT++KQ + +NL+VV+ +L + + L L L+ + R+SE++
Sbjct: 1670 LTLIKQEIEKEEENLQVVLRQMSKHKTELKNILDMLQLENHELQGLKLQHDQRVSELE 1727
Score = 33.5 bits (75), Expect = 0.39
Identities = 38/174 (21%), Positives = 74/174 (42%), Gaps = 17/174 (9%)
Query: 261 DRHLRTLQISYDALKDENSKLRRKLNEVQSFSEAQTEMVRTLERKLEAKMIKEESDYHDL 320
D+ LR+LQ L+ K L E+ A+ + L +K E + + D+
Sbjct: 1495 DQQLRSLQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCLSKKKEKLTEELQKLQKDI 1554
Query: 321 ESVVQQVEQNLELMTKRAVKAENHVVKLKQEISLLQAQVSNFQRENEALRCGQGASLTVV 380
E + + +L+++ + V + + E+ L++QV++ Q+E L G
Sbjct: 1555 EMAERNEDHHLQVLKESEVLLQAK----RAELEKLKSQVTSQQQEMAVLDRQLG------ 1604
Query: 381 KQNADVALQNLRVVMNSAQASIKQLVSGAETLNLVAEILKSIDRISEVKDEEED 434
+ L L+ M A+A +++ + ET E+ + + I EVK E+
Sbjct: 1605 --HKKEELHLLQGSMVQAKADLQEALRLGET-----EVTEKCNHIREVKSLLEE 1651
Score = 32.3 bits (72), Expect = 0.86
Identities = 34/176 (19%), Positives = 73/176 (41%), Gaps = 6/176 (3%)
Query: 266 TLQISYDALKDENSKLRRKLNEVQSFSEAQTEMVRTLERKLEAKMIKEESDYHDLESVVQ 325
T Q L++E + + KL + + + + + E KLE + + H LE +
Sbjct: 1924 TKQQQLQVLQNEIEENKLKLVQQEMMFQRLQKERESEESKLETSKVTLKEQQHQLEKELT 1983
Query: 326 QVEQNLELMTKRAVKAENHVVKLKQE---ISLLQAQVSNFQR---ENEALRCGQGASLTV 379
+ L+ + + + AE V L++E L+ +S +R E E + L
Sbjct: 1984 DQKSKLDQVLSKVLAAEERVRTLQEEERWCESLEKTLSQTKRQLSEREQQLVEKSGELLA 2043
Query: 380 VKQNADVALQNLRVVMNSAQASIKQLVSGAETLNLVAEILKSIDRISEVKDEEEDS 435
+++ AD + ++ N K+ +L +I +S + ++ ++E+S
Sbjct: 2044 LQKEADSMRADFSLLRNQFLTERKKAEKQVASLKEALKIQRSQLEKNLLEQKQENS 2099
Score = 29.6 bits (65), Expect = 5.6
Identities = 22/86 (25%), Positives = 42/86 (48%), Gaps = 6/86 (6%)
Query: 280 KLRRKLNEVQSF-SEAQTEMVRTLERKLEAKMIKEESDYHDLESVVQQVEQNLELMTKRA 338
K R +L E +EA++E+ T E+ A + D + + Q E + E + +RA
Sbjct: 1430 KRRSELREADRLLAEAESELSCTKEKTKNAV-----EKFTDAKRSLLQTESDAEELERRA 1484
Query: 339 VKAENHVVKLKQEISLLQAQVSNFQR 364
+ ++VK Q++ LQA + ++
Sbjct: 1485 QETAVNLVKADQQLRSLQADAKDLEQ 1510
>gi|157388975 coiled-coil domain containing 99 [Homo sapiens]
Length = 605
Score = 45.1 bits (105), Expect = 1e-04
Identities = 43/200 (21%), Positives = 92/200 (46%), Gaps = 28/200 (14%)
Query: 261 DRHLRTLQISYDALKDEN---SKLRRKLNEVQSFSEAQTEMVRTLERKLEAKMIKEESDY 317
+ L+ Q ++ +N ++L + NE+ + +E+ + TL+R++E K ES
Sbjct: 18 EERLKAAQYGLQLVESQNELQNQLDKCRNEMMTMTESYEQEKYTLQREVELKSRMLESLS 77
Query: 318 HDLESVVQQVEQNLELMTKRAVKAENHVV-KLKQEISLLQAQVS-----------NFQRE 365
+ E++ QQ + +LE + ++ ++ V +LK +I L+ ++ +
Sbjct: 78 CECEAIKQQQKMHLEKLEEQLSRSHGQEVNELKTKIEKLKVELDEARLSEKQLKHQVDHQ 137
Query: 366 NEALRCGQGASLTVVKQNAD-------VALQNLRVVMNSAQASIKQLVSGAETLN----- 413
E L C + L V+ + +ALQ M S + ++K+ V+ +
Sbjct: 138 KELLSC-KSEELRVMSERVQESMSSEMLALQIELTEMESMKTTLKEEVNELQYRQEQLEL 196
Query: 414 LVAEILKSIDRISEVKDEEE 433
L+ +++ +DR+ E K+E E
Sbjct: 197 LITNLMRQVDRLKEEKEERE 216
>gi|118498356 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 43.9 bits (102), Expect = 3e-04
Identities = 37/139 (26%), Positives = 60/139 (43%), Gaps = 13/139 (9%)
Query: 266 TLQISYDALKDENSKLRRKLNEVQSFSEAQTEMVRTLERKLEAKMIKEESDYHDLESVVQ 325
T + +A++ ENS L + EVQ Q + V E K + H+ + ++
Sbjct: 760 TKEEELNAIRTENSSLTK---EVQDLKAKQNDQVSFASLVEELKKV-----IHEKDGKIK 811
Query: 326 QVEQNLELMTKRAVKAENHVVKLKQEISLLQAQVSNFQRENEALRCGQGASLTVVKQNAD 385
VE+ LE + E V LKQEI L+ ++ N Q E Q S+T Q
Sbjct: 812 SVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEK-----AQQLSITSKVQELQ 866
Query: 386 VALQNLRVVMNSAQASIKQ 404
L+ MN+ +A +++
Sbjct: 867 NLLKGKEEQMNTMKAVLEE 885
Score = 34.3 bits (77), Expect = 0.23
Identities = 27/121 (22%), Positives = 58/121 (47%), Gaps = 7/121 (5%)
Query: 274 LKDENSKLRRKLNEVQSFSEAQTEMVRTLERKLEAKMIKEESDYHDLESV---VQQVEQN 330
LKD ++L++KL++ S + Q E + L+ +L + K ++ ++ + V + + +Q+
Sbjct: 1230 LKDLLTELQKKLDDSYSEAVRQNEELNLLKAQLNETLTKLRTEQNERQKVAGDLHKAQQS 1289
Query: 331 LELMTKRAVKAENHVVKLKQEISLLQAQVSNFQRENEALRCGQGASLTVVKQNADVALQN 390
LEL+ + VKA ++ + + S E E + ++T ++Q Q
Sbjct: 1290 LELIQSKIVKAAGDTTVIENSDVSPETESS----EKETMSVSLNQTVTQLQQLLQAVNQQ 1345
Query: 391 L 391
L
Sbjct: 1346 L 1346
Score = 33.1 bits (74), Expect = 0.51
Identities = 45/160 (28%), Positives = 63/160 (39%), Gaps = 35/160 (21%)
Query: 273 ALKDENSKLRRKLNEVQSFSEAQTEMVRTLERKLEAKMIKEESDYHDLESVVQQVEQNLE 332
A +D SK K NEVQS T+ TL K + + Q++ Q +E
Sbjct: 514 AQQDLQSKFVAKENEVQSLHSKLTD---TLVSK---------------QQLEQRLMQLME 555
Query: 333 LMTKRAVKAENHVVKLKQEISLLQAQVSNFQRENEALRC--GQGASLTVVKQNADVALQN 390
KR K E+ LQ QV + +NEAL+ Q S + +A V +
Sbjct: 556 SEQKRVNKEES-----------LQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEE 604
Query: 391 LRVVMNSAQASIKQ----LVSGAETLNLVAEILKSIDRIS 426
L V+ IKQ L S + L E LK I ++
Sbjct: 605 LHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNMN 644
>gi|118498368 kinectin 1 isoform c [Homo sapiens]
Length = 1300
Score = 43.9 bits (102), Expect = 3e-04
Identities = 37/139 (26%), Positives = 60/139 (43%), Gaps = 13/139 (9%)
Query: 266 TLQISYDALKDENSKLRRKLNEVQSFSEAQTEMVRTLERKLEAKMIKEESDYHDLESVVQ 325
T + +A++ ENS L + EVQ Q + V E K + H+ + ++
Sbjct: 760 TKEEELNAIRTENSSLTK---EVQDLKAKQNDQVSFASLVEELKKV-----IHEKDGKIK 811
Query: 326 QVEQNLELMTKRAVKAENHVVKLKQEISLLQAQVSNFQRENEALRCGQGASLTVVKQNAD 385
VE+ LE + E V LKQEI L+ ++ N Q E Q S+T Q
Sbjct: 812 SVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEK-----AQQLSITSKVQELQ 866
Query: 386 VALQNLRVVMNSAQASIKQ 404
L+ MN+ +A +++
Sbjct: 867 NLLKGKEEQMNTMKAVLEE 885
Score = 33.1 bits (74), Expect = 0.51
Identities = 45/160 (28%), Positives = 63/160 (39%), Gaps = 35/160 (21%)
Query: 273 ALKDENSKLRRKLNEVQSFSEAQTEMVRTLERKLEAKMIKEESDYHDLESVVQQVEQNLE 332
A +D SK K NEVQS T+ TL K + + Q++ Q +E
Sbjct: 514 AQQDLQSKFVAKENEVQSLHSKLTD---TLVSK---------------QQLEQRLMQLME 555
Query: 333 LMTKRAVKAENHVVKLKQEISLLQAQVSNFQRENEALRC--GQGASLTVVKQNADVALQN 390
KR K E+ LQ QV + +NEAL+ Q S + +A V +
Sbjct: 556 SEQKRVNKEES-----------LQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEE 604
Query: 391 LRVVMNSAQASIKQ----LVSGAETLNLVAEILKSIDRIS 426
L V+ IKQ L S + L E LK I ++
Sbjct: 605 LHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNMN 644
Score = 33.1 bits (74), Expect = 0.51
Identities = 30/144 (20%), Positives = 68/144 (47%), Gaps = 9/144 (6%)
Query: 276 DENSKLRRKLNEVQSFSEAQTEMVRTLERKLEAKMIKEESDYHDLESVVQQVEQNLELMT 335
DE+ K +++ + SE + E +R+ + +E ++ E ++ ++E ++E++ +
Sbjct: 1140 DESHKTIKQMQSSFTSSEQELERLRSENKDIE--NLRREREHLEMELEKAEMERSTYVTE 1197
Query: 336 KRAVKAE--NHVVKLKQEISLLQAQVSNFQRENEALRCGQ-----GASLTVVKQNADVAL 388
R +KA+ + KL+ E + Q + + ++L Q A T V +N+DV+
Sbjct: 1198 VRELKAQLNETLTKLRTEQNERQKVAGDLHKAQQSLELIQSKIVKAAGDTTVIENSDVSP 1257
Query: 389 QNLRVVMNSAQASIKQLVSGAETL 412
+ + S+ Q V+ + L
Sbjct: 1258 ETESSEKETMSVSLNQTVTQLQQL 1281
Score = 29.3 bits (64), Expect = 7.3
Identities = 26/131 (19%), Positives = 55/131 (41%), Gaps = 7/131 (5%)
Query: 264 LRTLQISYDALKDENSKLRRKLNEVQSFSEAQTEMVRTLERKLEAKMIKEESDYHDLESV 323
LR+ + L+ E L +L + + VR L+ +L + K ++ ++ + V
Sbjct: 1163 LRSENKDIENLRREREHLEMELEKAEMERSTYVTEVRELKAQLNETLTKLRTEQNERQKV 1222
Query: 324 ---VQQVEQNLELMTKRAVKAENHVVKLKQEISLLQAQVSNFQRENEALRCGQGASLTVV 380
+ + +Q+LEL+ + VKA ++ + + S E E + ++T +
Sbjct: 1223 AGDLHKAQQSLELIQSKIVKAAGDTTVIENSDVSPETESS----EKETMSVSLNQTVTQL 1278
Query: 381 KQNADVALQNL 391
+Q Q L
Sbjct: 1279 QQLLQAVNQQL 1289
>gi|33620775 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 43.9 bits (102), Expect = 3e-04
Identities = 37/139 (26%), Positives = 60/139 (43%), Gaps = 13/139 (9%)
Query: 266 TLQISYDALKDENSKLRRKLNEVQSFSEAQTEMVRTLERKLEAKMIKEESDYHDLESVVQ 325
T + +A++ ENS L + EVQ Q + V E K + H+ + ++
Sbjct: 760 TKEEELNAIRTENSSLTK---EVQDLKAKQNDQVSFASLVEELKKV-----IHEKDGKIK 811
Query: 326 QVEQNLELMTKRAVKAENHVVKLKQEISLLQAQVSNFQRENEALRCGQGASLTVVKQNAD 385
VE+ LE + E V LKQEI L+ ++ N Q E Q S+T Q
Sbjct: 812 SVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEK-----AQQLSITSKVQELQ 866
Query: 386 VALQNLRVVMNSAQASIKQ 404
L+ MN+ +A +++
Sbjct: 867 NLLKGKEEQMNTMKAVLEE 885
Score = 34.3 bits (77), Expect = 0.23
Identities = 27/121 (22%), Positives = 58/121 (47%), Gaps = 7/121 (5%)
Query: 274 LKDENSKLRRKLNEVQSFSEAQTEMVRTLERKLEAKMIKEESDYHDLESV---VQQVEQN 330
LKD ++L++KL++ S + Q E + L+ +L + K ++ ++ + V + + +Q+
Sbjct: 1230 LKDLLTELQKKLDDSYSEAVRQNEELNLLKAQLNETLTKLRTEQNERQKVAGDLHKAQQS 1289
Query: 331 LELMTKRAVKAENHVVKLKQEISLLQAQVSNFQRENEALRCGQGASLTVVKQNADVALQN 390
LEL+ + VKA ++ + + S E E + ++T ++Q Q
Sbjct: 1290 LELIQSKIVKAAGDTTVIENSDVSPETESS----EKETMSVSLNQTVTQLQQLLQAVNQQ 1345
Query: 391 L 391
L
Sbjct: 1346 L 1346
Score = 33.1 bits (74), Expect = 0.51
Identities = 45/160 (28%), Positives = 63/160 (39%), Gaps = 35/160 (21%)
Query: 273 ALKDENSKLRRKLNEVQSFSEAQTEMVRTLERKLEAKMIKEESDYHDLESVVQQVEQNLE 332
A +D SK K NEVQS T+ TL K + + Q++ Q +E
Sbjct: 514 AQQDLQSKFVAKENEVQSLHSKLTD---TLVSK---------------QQLEQRLMQLME 555
Query: 333 LMTKRAVKAENHVVKLKQEISLLQAQVSNFQRENEALRC--GQGASLTVVKQNADVALQN 390
KR K E+ LQ QV + +NEAL+ Q S + +A V +
Sbjct: 556 SEQKRVNKEES-----------LQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEE 604
Query: 391 LRVVMNSAQASIKQ----LVSGAETLNLVAEILKSIDRIS 426
L V+ IKQ L S + L E LK I ++
Sbjct: 605 LHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNMN 644
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 43.5 bits (101), Expect = 4e-04
Identities = 45/178 (25%), Positives = 82/178 (46%), Gaps = 27/178 (15%)
Query: 277 ENSKLRRKLN----------EVQSFSEAQTEMVRTLERKL---EAKMIKEESDYHDLESV 323
E++KLR ++N ++Q+ E E R L+R+L E ++ E +
Sbjct: 1559 EDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAA 1618
Query: 324 VQQVE---QNLELMTKRAVKAENHVVKLKQEISLLQAQVSNFQRENEALRCGQGASLTVV 380
+++E ++LEL A+K +K ++ LQAQ+ +FQRE E R +
Sbjct: 1619 KKKLEGDLKDLELQADSAIKGREEAIK---QLRKLQAQMKDFQRELEDARASRDEIFATA 1675
Query: 381 KQNADVA------LQNLRVVMNSAQASIKQLVSGAETLNLVAEILKSIDRISEVKDEE 432
K+N A L L+ + +A+ + KQ + E L E+ S+ + ++DE+
Sbjct: 1676 KENEKKAKSLEADLMQLQEDLAAAERARKQ--ADLEKEELAEELASSLSGRNALQDEK 1731
Score = 37.4 bits (85), Expect = 0.027
Identities = 37/169 (21%), Positives = 74/169 (43%), Gaps = 25/169 (14%)
Query: 261 DRHLRTLQISYDALKDENSKLRRKLN-EVQSFSEAQTEMVRTLERK---------LEAKM 310
+ L+ L+ + L +E + L+ +L E + ++EA+ VR +K +EA++
Sbjct: 872 ENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARL 931
Query: 311 IKEE--------------SDYHDLESVVQQVEQNLELMTKRAVKAENHVVKLKQEISLLQ 356
+EE DLE +++ E + + V AE + KL+ EI ++
Sbjct: 932 EEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMD 991
Query: 357 AQVSNFQRENEALRCGQGASLTVVKQNADVALQNLRVVMNSAQASIKQL 405
Q + +E + L + + LT + +NL + N ++ I +L
Sbjct: 992 DQNNKLSKERKLLE-ERISDLTTNLAEEEEKAKNLTKLKNKHESMISEL 1039
Score = 30.8 bits (68), Expect = 2.5
Identities = 26/106 (24%), Positives = 52/106 (49%), Gaps = 5/106 (4%)
Query: 264 LRTLQISYDALKDENSKL--RRKLNEVQSFSEAQTEMVRTLERKLEAKMIKE--ESDYHD 319
++ L+ + D+N+KL RKL E + S+ T + E+ +K ES +
Sbjct: 980 IKKLEDEILVMDDQNNKLSKERKLLE-ERISDLTTNLAEEEEKAKNLTKLKNKHESMISE 1038
Query: 320 LESVVQQVEQNLELMTKRAVKAENHVVKLKQEISLLQAQVSNFQRE 365
LE +++ E++ + + K K E ++I+ LQAQ++ + +
Sbjct: 1039 LEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQ 1084
Score = 29.3 bits (64), Expect = 7.3
Identities = 33/139 (23%), Positives = 58/139 (41%), Gaps = 34/139 (24%)
Query: 263 HLRTLQISYDALKDENSKLRRKLNEVQSFSEAQT--------EMVRTLERKLEA------ 308
+L Q +D L E + K + + +EA+ + R LE LEA
Sbjct: 1445 NLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELER 1504
Query: 309 --KMIKEE------------SDYHDLESVVQQVEQNLELMTKRAVKAENHV-----VKLK 349
KM+K E + H+LE + +E +E M + + E+ + KL+
Sbjct: 1505 TNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLR 1564
Query: 350 QEISLLQAQVSNFQRENEA 368
E++ +QA F+R+ +A
Sbjct: 1565 LEVN-MQALKGQFERDLQA 1582
Score = 28.9 bits (63), Expect = 9.6
Identities = 34/181 (18%), Positives = 76/181 (41%), Gaps = 21/181 (11%)
Query: 267 LQISYDALKDENSKLRRKLNEVQSFSEAQTEM-----VRTLERKLEAKMIKEESDYHDLE 321
+Q+ D E ++ + L + + E + + ++ +R+LEA++ + LE
Sbjct: 1690 MQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQ-------LE 1742
Query: 322 SVVQQVEQNLELMTKRAVKAENHVVKLKQEISLLQAQV-------SNFQRENEALRCGQG 374
+++ + N+E M+ R KA +L E++ ++ +R+N+ LR
Sbjct: 1743 EELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLH 1802
Query: 375 ASLTVVKQ--NADVALQNLRVVMNSAQASIKQLVSGAETLNLVAEILKSIDRISEVKDEE 432
VK + +A ++ Q + A T +L + K + + +V+DE
Sbjct: 1803 EMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDER 1862
Query: 433 E 433
+
Sbjct: 1863 K 1863
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 43.5 bits (101), Expect = 4e-04
Identities = 45/178 (25%), Positives = 82/178 (46%), Gaps = 27/178 (15%)
Query: 277 ENSKLRRKLN----------EVQSFSEAQTEMVRTLERKL---EAKMIKEESDYHDLESV 323
E++KLR ++N ++Q+ E E R L+R+L E ++ E +
Sbjct: 1566 EDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAA 1625
Query: 324 VQQVE---QNLELMTKRAVKAENHVVKLKQEISLLQAQVSNFQRENEALRCGQGASLTVV 380
+++E ++LEL A+K +K ++ LQAQ+ +FQRE E R +
Sbjct: 1626 KKKLEGDLKDLELQADSAIKGREEAIK---QLRKLQAQMKDFQRELEDARASRDEIFATA 1682
Query: 381 KQNADVA------LQNLRVVMNSAQASIKQLVSGAETLNLVAEILKSIDRISEVKDEE 432
K+N A L L+ + +A+ + KQ + E L E+ S+ + ++DE+
Sbjct: 1683 KENEKKAKSLEADLMQLQEDLAAAERARKQ--ADLEKEELAEELASSLSGRNALQDEK 1738
Score = 37.4 bits (85), Expect = 0.027
Identities = 37/169 (21%), Positives = 74/169 (43%), Gaps = 25/169 (14%)
Query: 261 DRHLRTLQISYDALKDENSKLRRKLN-EVQSFSEAQTEMVRTLERK---------LEAKM 310
+ L+ L+ + L +E + L+ +L E + ++EA+ VR +K +EA++
Sbjct: 879 ENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARL 938
Query: 311 IKEE--------------SDYHDLESVVQQVEQNLELMTKRAVKAENHVVKLKQEISLLQ 356
+EE DLE +++ E + + V AE + KL+ EI ++
Sbjct: 939 EEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMD 998
Query: 357 AQVSNFQRENEALRCGQGASLTVVKQNADVALQNLRVVMNSAQASIKQL 405
Q + +E + L + + LT + +NL + N ++ I +L
Sbjct: 999 DQNNKLSKERKLLE-ERISDLTTNLAEEEEKAKNLTKLKNKHESMISEL 1046
Score = 30.8 bits (68), Expect = 2.5
Identities = 26/106 (24%), Positives = 52/106 (49%), Gaps = 5/106 (4%)
Query: 264 LRTLQISYDALKDENSKL--RRKLNEVQSFSEAQTEMVRTLERKLEAKMIKE--ESDYHD 319
++ L+ + D+N+KL RKL E + S+ T + E+ +K ES +
Sbjct: 987 IKKLEDEILVMDDQNNKLSKERKLLE-ERISDLTTNLAEEEEKAKNLTKLKNKHESMISE 1045
Query: 320 LESVVQQVEQNLELMTKRAVKAENHVVKLKQEISLLQAQVSNFQRE 365
LE +++ E++ + + K K E ++I+ LQAQ++ + +
Sbjct: 1046 LEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQ 1091
Score = 29.3 bits (64), Expect = 7.3
Identities = 33/139 (23%), Positives = 58/139 (41%), Gaps = 34/139 (24%)
Query: 263 HLRTLQISYDALKDENSKLRRKLNEVQSFSEAQT--------EMVRTLERKLEA------ 308
+L Q +D L E + K + + +EA+ + R LE LEA
Sbjct: 1452 NLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELER 1511
Query: 309 --KMIKEE------------SDYHDLESVVQQVEQNLELMTKRAVKAENHV-----VKLK 349
KM+K E + H+LE + +E +E M + + E+ + KL+
Sbjct: 1512 TNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLR 1571
Query: 350 QEISLLQAQVSNFQRENEA 368
E++ +QA F+R+ +A
Sbjct: 1572 LEVN-MQALKGQFERDLQA 1589
Score = 28.9 bits (63), Expect = 9.6
Identities = 34/181 (18%), Positives = 76/181 (41%), Gaps = 21/181 (11%)
Query: 267 LQISYDALKDENSKLRRKLNEVQSFSEAQTEM-----VRTLERKLEAKMIKEESDYHDLE 321
+Q+ D E ++ + L + + E + + ++ +R+LEA++ + LE
Sbjct: 1697 MQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQ-------LE 1749
Query: 322 SVVQQVEQNLELMTKRAVKAENHVVKLKQEISLLQAQV-------SNFQRENEALRCGQG 374
+++ + N+E M+ R KA +L E++ ++ +R+N+ LR
Sbjct: 1750 EELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLH 1809
Query: 375 ASLTVVKQ--NADVALQNLRVVMNSAQASIKQLVSGAETLNLVAEILKSIDRISEVKDEE 432
VK + +A ++ Q + A T +L + K + + +V+DE
Sbjct: 1810 EMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDER 1869
Query: 433 E 433
+
Sbjct: 1870 K 1870
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 43.5 bits (101), Expect = 4e-04
Identities = 45/178 (25%), Positives = 82/178 (46%), Gaps = 27/178 (15%)
Query: 277 ENSKLRRKLN----------EVQSFSEAQTEMVRTLERKL---EAKMIKEESDYHDLESV 323
E++KLR ++N ++Q+ E E R L+R+L E ++ E +
Sbjct: 1566 EDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAA 1625
Query: 324 VQQVE---QNLELMTKRAVKAENHVVKLKQEISLLQAQVSNFQRENEALRCGQGASLTVV 380
+++E ++LEL A+K +K ++ LQAQ+ +FQRE E R +
Sbjct: 1626 KKKLEGDLKDLELQADSAIKGREEAIK---QLRKLQAQMKDFQRELEDARASRDEIFATA 1682
Query: 381 KQNADVA------LQNLRVVMNSAQASIKQLVSGAETLNLVAEILKSIDRISEVKDEE 432
K+N A L L+ + +A+ + KQ + E L E+ S+ + ++DE+
Sbjct: 1683 KENEKKAKSLEADLMQLQEDLAAAERARKQ--ADLEKEELAEELASSLSGRNALQDEK 1738
Score = 37.4 bits (85), Expect = 0.027
Identities = 37/169 (21%), Positives = 74/169 (43%), Gaps = 25/169 (14%)
Query: 261 DRHLRTLQISYDALKDENSKLRRKLN-EVQSFSEAQTEMVRTLERK---------LEAKM 310
+ L+ L+ + L +E + L+ +L E + ++EA+ VR +K +EA++
Sbjct: 879 ENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARL 938
Query: 311 IKEE--------------SDYHDLESVVQQVEQNLELMTKRAVKAENHVVKLKQEISLLQ 356
+EE DLE +++ E + + V AE + KL+ EI ++
Sbjct: 939 EEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMD 998
Query: 357 AQVSNFQRENEALRCGQGASLTVVKQNADVALQNLRVVMNSAQASIKQL 405
Q + +E + L + + LT + +NL + N ++ I +L
Sbjct: 999 DQNNKLSKERKLLE-ERISDLTTNLAEEEEKAKNLTKLKNKHESMISEL 1046
Score = 30.8 bits (68), Expect = 2.5
Identities = 26/106 (24%), Positives = 52/106 (49%), Gaps = 5/106 (4%)
Query: 264 LRTLQISYDALKDENSKL--RRKLNEVQSFSEAQTEMVRTLERKLEAKMIKE--ESDYHD 319
++ L+ + D+N+KL RKL E + S+ T + E+ +K ES +
Sbjct: 987 IKKLEDEILVMDDQNNKLSKERKLLE-ERISDLTTNLAEEEEKAKNLTKLKNKHESMISE 1045
Query: 320 LESVVQQVEQNLELMTKRAVKAENHVVKLKQEISLLQAQVSNFQRE 365
LE +++ E++ + + K K E ++I+ LQAQ++ + +
Sbjct: 1046 LEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQ 1091
Score = 29.3 bits (64), Expect = 7.3
Identities = 33/139 (23%), Positives = 58/139 (41%), Gaps = 34/139 (24%)
Query: 263 HLRTLQISYDALKDENSKLRRKLNEVQSFSEAQT--------EMVRTLERKLEA------ 308
+L Q +D L E + K + + +EA+ + R LE LEA
Sbjct: 1452 NLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELER 1511
Query: 309 --KMIKEE------------SDYHDLESVVQQVEQNLELMTKRAVKAENHV-----VKLK 349
KM+K E + H+LE + +E +E M + + E+ + KL+
Sbjct: 1512 TNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLR 1571
Query: 350 QEISLLQAQVSNFQRENEA 368
E++ +QA F+R+ +A
Sbjct: 1572 LEVN-MQALKGQFERDLQA 1589
Score = 28.9 bits (63), Expect = 9.6
Identities = 34/181 (18%), Positives = 76/181 (41%), Gaps = 21/181 (11%)
Query: 267 LQISYDALKDENSKLRRKLNEVQSFSEAQTEM-----VRTLERKLEAKMIKEESDYHDLE 321
+Q+ D E ++ + L + + E + + ++ +R+LEA++ + LE
Sbjct: 1697 MQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQ-------LE 1749
Query: 322 SVVQQVEQNLELMTKRAVKAENHVVKLKQEISLLQAQV-------SNFQRENEALRCGQG 374
+++ + N+E M+ R KA +L E++ ++ +R+N+ LR
Sbjct: 1750 EELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLH 1809
Query: 375 ASLTVVKQ--NADVALQNLRVVMNSAQASIKQLVSGAETLNLVAEILKSIDRISEVKDEE 432
VK + +A ++ Q + A T +L + K + + +V+DE
Sbjct: 1810 EMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDER 1869
Query: 433 E 433
+
Sbjct: 1870 K 1870
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 43.5 bits (101), Expect = 4e-04
Identities = 45/178 (25%), Positives = 82/178 (46%), Gaps = 27/178 (15%)
Query: 277 ENSKLRRKLN----------EVQSFSEAQTEMVRTLERKL---EAKMIKEESDYHDLESV 323
E++KLR ++N ++Q+ E E R L+R+L E ++ E +
Sbjct: 1559 EDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAA 1618
Query: 324 VQQVE---QNLELMTKRAVKAENHVVKLKQEISLLQAQVSNFQRENEALRCGQGASLTVV 380
+++E ++LEL A+K +K ++ LQAQ+ +FQRE E R +
Sbjct: 1619 KKKLEGDLKDLELQADSAIKGREEAIK---QLRKLQAQMKDFQRELEDARASRDEIFATA 1675
Query: 381 KQNADVA------LQNLRVVMNSAQASIKQLVSGAETLNLVAEILKSIDRISEVKDEE 432
K+N A L L+ + +A+ + KQ + E L E+ S+ + ++DE+
Sbjct: 1676 KENEKKAKSLEADLMQLQEDLAAAERARKQ--ADLEKEELAEELASSLSGRNALQDEK 1731
Score = 37.4 bits (85), Expect = 0.027
Identities = 37/169 (21%), Positives = 74/169 (43%), Gaps = 25/169 (14%)
Query: 261 DRHLRTLQISYDALKDENSKLRRKLN-EVQSFSEAQTEMVRTLERK---------LEAKM 310
+ L+ L+ + L +E + L+ +L E + ++EA+ VR +K +EA++
Sbjct: 872 ENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARL 931
Query: 311 IKEE--------------SDYHDLESVVQQVEQNLELMTKRAVKAENHVVKLKQEISLLQ 356
+EE DLE +++ E + + V AE + KL+ EI ++
Sbjct: 932 EEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMD 991
Query: 357 AQVSNFQRENEALRCGQGASLTVVKQNADVALQNLRVVMNSAQASIKQL 405
Q + +E + L + + LT + +NL + N ++ I +L
Sbjct: 992 DQNNKLSKERKLLE-ERISDLTTNLAEEEEKAKNLTKLKNKHESMISEL 1039
Score = 30.8 bits (68), Expect = 2.5
Identities = 26/106 (24%), Positives = 52/106 (49%), Gaps = 5/106 (4%)
Query: 264 LRTLQISYDALKDENSKL--RRKLNEVQSFSEAQTEMVRTLERKLEAKMIKE--ESDYHD 319
++ L+ + D+N+KL RKL E + S+ T + E+ +K ES +
Sbjct: 980 IKKLEDEILVMDDQNNKLSKERKLLE-ERISDLTTNLAEEEEKAKNLTKLKNKHESMISE 1038
Query: 320 LESVVQQVEQNLELMTKRAVKAENHVVKLKQEISLLQAQVSNFQRE 365
LE +++ E++ + + K K E ++I+ LQAQ++ + +
Sbjct: 1039 LEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQ 1084
Score = 29.3 bits (64), Expect = 7.3
Identities = 33/139 (23%), Positives = 58/139 (41%), Gaps = 34/139 (24%)
Query: 263 HLRTLQISYDALKDENSKLRRKLNEVQSFSEAQT--------EMVRTLERKLEA------ 308
+L Q +D L E + K + + +EA+ + R LE LEA
Sbjct: 1445 NLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELER 1504
Query: 309 --KMIKEE------------SDYHDLESVVQQVEQNLELMTKRAVKAENHV-----VKLK 349
KM+K E + H+LE + +E +E M + + E+ + KL+
Sbjct: 1505 TNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLR 1564
Query: 350 QEISLLQAQVSNFQRENEA 368
E++ +QA F+R+ +A
Sbjct: 1565 LEVN-MQALKGQFERDLQA 1582
Score = 28.9 bits (63), Expect = 9.6
Identities = 34/181 (18%), Positives = 76/181 (41%), Gaps = 21/181 (11%)
Query: 267 LQISYDALKDENSKLRRKLNEVQSFSEAQTEM-----VRTLERKLEAKMIKEESDYHDLE 321
+Q+ D E ++ + L + + E + + ++ +R+LEA++ + LE
Sbjct: 1690 MQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQ-------LE 1742
Query: 322 SVVQQVEQNLELMTKRAVKAENHVVKLKQEISLLQAQV-------SNFQRENEALRCGQG 374
+++ + N+E M+ R KA +L E++ ++ +R+N+ LR
Sbjct: 1743 EELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLH 1802
Query: 375 ASLTVVKQ--NADVALQNLRVVMNSAQASIKQLVSGAETLNLVAEILKSIDRISEVKDEE 432
VK + +A ++ Q + A T +L + K + + +V+DE
Sbjct: 1803 EMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDER 1862
Query: 433 E 433
+
Sbjct: 1863 K 1863
>gi|219689136 coiled-coil domain containing 68 [Homo sapiens]
Length = 335
Score = 43.1 bits (100), Expect = 5e-04
Identities = 39/150 (26%), Positives = 78/150 (52%), Gaps = 21/150 (14%)
Query: 275 KDENSKLRRKLNEVQSFSEAQTEMVRTLERKLEAKMIKEESDYHDLESVVQQVEQNLELM 334
K E+SK ++N+++ + + + V L + E K+ ++ S +LE++VQ++E+ +
Sbjct: 148 KQEDSKQLLQVNKLEKEQKLK-QHVENLNQVAE-KLEEKHSQITELENLVQRMEKEKRTL 205
Query: 335 TKRAVKAENHVVKLK-------------QEISLLQAQVSNFQ----RENEALR--CGQGA 375
+R + EN +++LK +EIS+LQ Q+S+ Q +++ LR +
Sbjct: 206 LERKLSLENKLLQLKSSATYGKSCQDLQREISILQEQISHLQFVIHSQHQNLRSVIQEME 265
Query: 376 SLTVVKQNADVALQNLRVVMNSAQASIKQL 405
L + D ++NLR +N +A K+L
Sbjct: 266 GLKNNLKEQDKRIENLREKVNILEAQNKEL 295
>gi|13376818 coiled-coil domain containing 68 [Homo sapiens]
Length = 335
Score = 43.1 bits (100), Expect = 5e-04
Identities = 39/150 (26%), Positives = 78/150 (52%), Gaps = 21/150 (14%)
Query: 275 KDENSKLRRKLNEVQSFSEAQTEMVRTLERKLEAKMIKEESDYHDLESVVQQVEQNLELM 334
K E+SK ++N+++ + + + V L + E K+ ++ S +LE++VQ++E+ +
Sbjct: 148 KQEDSKQLLQVNKLEKEQKLK-QHVENLNQVAE-KLEEKHSQITELENLVQRMEKEKRTL 205
Query: 335 TKRAVKAENHVVKLK-------------QEISLLQAQVSNFQ----RENEALR--CGQGA 375
+R + EN +++LK +EIS+LQ Q+S+ Q +++ LR +
Sbjct: 206 LERKLSLENKLLQLKSSATYGKSCQDLQREISILQEQISHLQFVIHSQHQNLRSVIQEME 265
Query: 376 SLTVVKQNADVALQNLRVVMNSAQASIKQL 405
L + D ++NLR +N +A K+L
Sbjct: 266 GLKNNLKEQDKRIENLREKVNILEAQNKEL 295
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 42.4 bits (98), Expect = 8e-04
Identities = 36/128 (28%), Positives = 62/128 (48%), Gaps = 22/128 (17%)
Query: 267 LQISYDALKDENSKLRRKLNEVQSFSEAQTEMVRTLERKLEAKMIKEESDYHDLESVVQQ 326
L++SY L EN +L++ L E + ++ LE +L+ DLE Q
Sbjct: 754 LEVSYQGLDIENQRLQKTL-------ENSNKKIQQLESELQ-----------DLEMENQT 795
Query: 327 VEQNLE---LMTKRAVKAENHVVKLKQEISLLQAQVSNFQRENEALRCGQGASLTVVKQN 383
+++NLE + +KR + E L+QE S L+ ++EN+ LR T +++N
Sbjct: 796 LQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEEN 855
Query: 384 ADVALQNL 391
+V + NL
Sbjct: 856 -NVKIGNL 862
Score = 35.0 bits (79), Expect = 0.13
Identities = 39/176 (22%), Positives = 78/176 (44%), Gaps = 16/176 (9%)
Query: 261 DRHLRTLQISYDALKDENSKLRRKLNEVQSFSEAQTEMVRTLE--RKLEAKMIKEESDYH 318
+R R L+ + D+ K+ +L E E E+ R +E + KM + + +
Sbjct: 669 ERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENK 728
Query: 319 DLESVVQQVEQNLELMTKRAVKAENHVVKLKQEISLLQAQVSNFQRENEALRCGQGASLT 378
+LES +Q+++ LEL+ K E L+ EN+ L+ S
Sbjct: 729 ELESEKEQLKKGLELLKASFKKTER-----------LEVSYQGLDIENQRLQKTLENSNK 777
Query: 379 VVKQNADVALQNLRVVMNSAQASIKQLVSGAETLNLVAEILKSIDRISEVKDEEED 434
++Q + LQ+L + + Q ++++L ++ L + + KS+++ E E+D
Sbjct: 778 KIQQ-LESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQ--ETSQLEKD 830
Score = 35.0 bits (79), Expect = 0.13
Identities = 28/140 (20%), Positives = 65/140 (46%), Gaps = 15/140 (10%)
Query: 262 RHLRTLQISYDALKDENSKLRRKLNEV----------QSFSEAQTEMVRTLERKLEAKMI 311
+ L+T++ +Y+ALK + R + + E E+++ +R +E +
Sbjct: 995 QELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERN 1054
Query: 312 KE--ESDYHDLESVVQQVEQNLELMTKRAVKAENHVVKLKQEISLLQAQVSNFQRENEAL 369
+++ L++ ++Q+E + + + + V L+++ + LQ Q + Q EN L
Sbjct: 1055 NATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTL 1114
Query: 370 RCGQGASLTVVKQNADVALQ 389
S +++ QNA + +Q
Sbjct: 1115 ---NSQSTSLMNQNAQLLIQ 1131
Score = 34.7 bits (78), Expect = 0.17
Identities = 38/161 (23%), Positives = 79/161 (49%), Gaps = 16/161 (9%)
Query: 257 ESLGDRHLRTLQISYDALKDENSKLRRKLNEVQSFSEAQTEM-VRTLER--KLEAKMIKE 313
E+L + R ++I L+ EN L + ++ ++ S+ E V+ +E+ K+ + IKE
Sbjct: 543 ETLRENSERQIKI----LEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKE 598
Query: 314 ESD-YHDLESVVQQVEQNLELMTK---RAVKAENHVVKLKQEISLLQAQVSNFQRENEAL 369
S +E +Q+++ LE + RA + EN + L++E LLQ +++N + E +
Sbjct: 599 TSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKI 658
Query: 370 RCGQGASLTVVKQNADV-----ALQNLRVVMNSAQASIKQL 405
+ + + ++N + + +NL + S + QL
Sbjct: 659 EALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQL 699
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 42.4 bits (98), Expect = 8e-04
Identities = 36/128 (28%), Positives = 62/128 (48%), Gaps = 22/128 (17%)
Query: 267 LQISYDALKDENSKLRRKLNEVQSFSEAQTEMVRTLERKLEAKMIKEESDYHDLESVVQQ 326
L++SY L EN +L++ L E + ++ LE +L+ DLE Q
Sbjct: 754 LEVSYQGLDIENQRLQKTL-------ENSNKKIQQLESELQ-----------DLEMENQT 795
Query: 327 VEQNLE---LMTKRAVKAENHVVKLKQEISLLQAQVSNFQRENEALRCGQGASLTVVKQN 383
+++NLE + +KR + E L+QE S L+ ++EN+ LR T +++N
Sbjct: 796 LQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEEN 855
Query: 384 ADVALQNL 391
+V + NL
Sbjct: 856 -NVKIGNL 862
Score = 35.0 bits (79), Expect = 0.13
Identities = 39/176 (22%), Positives = 78/176 (44%), Gaps = 16/176 (9%)
Query: 261 DRHLRTLQISYDALKDENSKLRRKLNEVQSFSEAQTEMVRTLE--RKLEAKMIKEESDYH 318
+R R L+ + D+ K+ +L E E E+ R +E + KM + + +
Sbjct: 669 ERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENK 728
Query: 319 DLESVVQQVEQNLELMTKRAVKAENHVVKLKQEISLLQAQVSNFQRENEALRCGQGASLT 378
+LES +Q+++ LEL+ K E L+ EN+ L+ S
Sbjct: 729 ELESEKEQLKKGLELLKASFKKTER-----------LEVSYQGLDIENQRLQKTLENSNK 777
Query: 379 VVKQNADVALQNLRVVMNSAQASIKQLVSGAETLNLVAEILKSIDRISEVKDEEED 434
++Q + LQ+L + + Q ++++L ++ L + + KS+++ E E+D
Sbjct: 778 KIQQ-LESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQ--ETSQLEKD 830
Score = 35.0 bits (79), Expect = 0.13
Identities = 28/140 (20%), Positives = 65/140 (46%), Gaps = 15/140 (10%)
Query: 262 RHLRTLQISYDALKDENSKLRRKLNEV----------QSFSEAQTEMVRTLERKLEAKMI 311
+ L+T++ +Y+ALK + R + + E E+++ +R +E +
Sbjct: 994 QELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERN 1053
Query: 312 KE--ESDYHDLESVVQQVEQNLELMTKRAVKAENHVVKLKQEISLLQAQVSNFQRENEAL 369
+++ L++ ++Q+E + + + + V L+++ + LQ Q + Q EN L
Sbjct: 1054 NATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTL 1113
Query: 370 RCGQGASLTVVKQNADVALQ 389
S +++ QNA + +Q
Sbjct: 1114 ---NSQSTSLMNQNAQLLIQ 1130
Score = 34.7 bits (78), Expect = 0.17
Identities = 38/161 (23%), Positives = 79/161 (49%), Gaps = 16/161 (9%)
Query: 257 ESLGDRHLRTLQISYDALKDENSKLRRKLNEVQSFSEAQTEM-VRTLER--KLEAKMIKE 313
E+L + R ++I L+ EN L + ++ ++ S+ E V+ +E+ K+ + IKE
Sbjct: 543 ETLRENSERQIKI----LEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKE 598
Query: 314 ESD-YHDLESVVQQVEQNLELMTK---RAVKAENHVVKLKQEISLLQAQVSNFQRENEAL 369
S +E +Q+++ LE + RA + EN + L++E LLQ +++N + E +
Sbjct: 599 TSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKI 658
Query: 370 RCGQGASLTVVKQNADV-----ALQNLRVVMNSAQASIKQL 405
+ + + ++N + + +NL + S + QL
Sbjct: 659 EALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQL 699
>gi|4503593 epidermal growth factor receptor pathway substrate 15
isoform A [Homo sapiens]
Length = 896
Score = 42.0 bits (97), Expect = 0.001
Identities = 30/150 (20%), Positives = 69/150 (46%), Gaps = 4/150 (2%)
Query: 218 PSELAGPESLPSWALSDTDSRVSPASPAGSPSA--DFAVHGESLGDRHLRTLQISYDALK 275
P + PE +P + + +SP SA + + D + D LK
Sbjct: 299 PPHVLTPEMIPPSDRASLQKNIIGSSPVADFSAIKELDTLNNEIVDLQREKNNVEQD-LK 357
Query: 276 DENSKLRRKLNEVQSFSEAQTEMVRTLERKLEAKMIKEESDYHDLESVVQQVEQNLELMT 335
++ ++++ +EVQ + + + T +KL+A+ + + +L+ Q+E+ L+ +
Sbjct: 358 EKEDTIKQRTSEVQDLQD-EVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQLKEVR 416
Query: 336 KRAVKAENHVVKLKQEISLLQAQVSNFQRE 365
K+ + + LK E++ ++Q+S ++ E
Sbjct: 417 KKCAEEAQLISSLKAELTSQESQISTYEEE 446
>gi|154354990 ankyrin repeat domain 26 [Homo sapiens]
Length = 1710
Score = 42.0 bits (97), Expect = 0.001
Identities = 41/179 (22%), Positives = 79/179 (44%), Gaps = 18/179 (10%)
Query: 253 AVHGESLGDRHLRTLQISYDALKDENSKLRRKLNEVQSFSEAQTEMVRTLERKLEAKMIK 312
A+H + R L++++ +DE S+L+ K+N S + E++ K E+K+
Sbjct: 1016 AIHDRDQSETSKRELELAFQRARDECSRLQDKMNFDVSNLKDNNEILSQQLFKTESKLNS 1075
Query: 313 EESDYH-----------DLESVVQQVEQNLELMTKRAVKAENHVVKLKQEI---SLLQAQ 358
E ++H LE V + + Q M + K +N VK+ + I ++ +
Sbjct: 1076 LEIEFHHTRDALREKTLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGKQESVEER 1135
Query: 359 VSNFQRENEALRCGQGASLTVVKQNADVALQNLRVVMNSAQASIKQLVSGAETLNLVAE 417
+S Q EN LR L AD + + + + A +++L + +E +L+ E
Sbjct: 1136 LSQLQSENMLLR----QQLDDAHNKADNKEKTVINIQDQFHAIVQKLQAESEKQSLLLE 1190
Score = 29.6 bits (65), Expect = 5.6
Identities = 32/147 (21%), Positives = 67/147 (45%), Gaps = 15/147 (10%)
Query: 302 LERKLEAKMIKEESDYHDLESVVQQVEQNLELMTKRAVKAENHVVKLKQEIS---LLQAQ 358
+E K ++K + E +++ + + EL+T + K E+ V L++E+S +++Q
Sbjct: 717 MECKDSVSLLKIQDAALSCERLLELKKNHCELLTVKIKKMEDKVNVLQRELSETKEIKSQ 776
Query: 359 VSNFQRENEALRCGQGASLT---VVKQNADVALQNLRVVMNSAQASIK-------QLVSG 408
+ + + E E C SL ++NAD + +R + + + QL
Sbjct: 777 LEHQKVEWERELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKEVEVKQQLELS 836
Query: 409 AETLNLVAEILKSIDRISEVKDEEEDS 435
+TL + +KS +++V E D+
Sbjct: 837 LQTLEMELRTVKS--NLNQVVQERNDA 861
>gi|89357932 keratin 5b [Homo sapiens]
Length = 520
Score = 41.6 bits (96), Expect = 0.001
Identities = 27/118 (22%), Positives = 62/118 (52%), Gaps = 7/118 (5%)
Query: 286 NEVQSFSEAQTEMVRTLERKLEAKMIKEESDYHDLESVVQQVEQNLELMTKRAVKAENHV 345
N FS TE+ E + + E+ Y ++ Q+++ + +L R + + +
Sbjct: 273 NRYLDFSSIITEVRARYEEIARSSKAEAEALY---QTKYQELQVSAQLHGDRMQETKVQI 329
Query: 346 VKLKQEISLLQAQVSNFQRENEALRCGQGASLTVVKQNADVALQNLRVVMNSAQASIK 403
+L QEI LQ+Q N +++N +L+ A++T +Q ++AL++ + ++ +A+++
Sbjct: 330 SQLHQEIQRLQSQTENLKKQNASLQ----AAITDAEQRGELALKDAQAKVDELEAALR 383
>gi|7705415 hook homolog 1 [Homo sapiens]
Length = 728
Score = 41.6 bits (96), Expect = 0.001
Identities = 40/174 (22%), Positives = 84/174 (48%), Gaps = 13/174 (7%)
Query: 272 DALKDENSKLRRKLNEVQSFSEAQTEMVRTLERKLE--AKMIKEESDYHDLESVVQQVEQ 329
+ L+++ + RK+NE+++ E +R L++++E K ++E+ + ES +++Q
Sbjct: 490 EELQEQLEQKHRKMNELETEQRLSKERIRELQQQIEDLQKSLQEQGSKSEGES-SSKLKQ 548
Query: 330 NLELMTKRAVKAENHVVKLKQEISLLQAQVS-NFQREN--EALRCGQGASLTVVKQNADV 386
LE ++ + + K ++ I LQ ++ N Q+ N EA + + +++ +
Sbjct: 549 KLEAHMEKLTEVHEELQKKQELIEDLQPDINQNVQKINELEAALQKKDEDMKAMEERYKM 608
Query: 387 ALQNLRVV-------MNSAQASIKQLVSGAETLNLVAEILKSIDRISEVKDEEE 433
L+ R V +N A A I L EIL+S ++++ +D EE
Sbjct: 609 YLEKARNVIKTLDPKLNPASAEIMLLRKQLAEKERRIEILESECKVAKFRDYEE 662
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 41.2 bits (95), Expect = 0.002
Identities = 34/139 (24%), Positives = 61/139 (43%), Gaps = 5/139 (3%)
Query: 272 DALKDENSKLRRKLNEVQSFSEAQTEMVRTLERKLEAKMIKEESDYHDLESVVQQVEQNL 331
D L +L K+ EV +E + E + +L AK K E + +L+ + +E L
Sbjct: 907 DQLIKAKFQLEAKIKEVTERAEDEEE----INAELTAKKRKLEDECSELKKDIDDLELTL 962
Query: 332 ELMTKRAVKAENHVVKLKQEISLLQAQVSNFQRENEALRCGQGASLTVVKQNADVALQNL 391
+ K EN V L +E+S L ++ RE +AL+ +L ++ D + +L
Sbjct: 963 AKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEED-KVNSL 1021
Query: 392 RVVMNSAQASIKQLVSGAE 410
+ + ++ L S E
Sbjct: 1022 NKTKSKLEQQVEDLESSLE 1040
Score = 38.5 bits (88), Expect = 0.012
Identities = 35/143 (24%), Positives = 71/143 (49%), Gaps = 15/143 (10%)
Query: 255 HGESLGDRHLRTLQISYDALKDENSKLRRKLNEVQSFSEAQTEMVRTLER---KLEAKMI 311
H ++L D L+ + ++L SKL +++ +++S E + ++ LER KLE +
Sbjct: 1004 HQQALDD--LQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLK 1061
Query: 312 KEESDYHDLESVVQQVEQNLELMTKRAVKAENHV-------VKLKQEISLLQAQVSNFQR 364
+ DLE+ QQ+++ L+ + ++ V ++ +++I LQA++ +
Sbjct: 1062 LAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEE 1121
Query: 365 ENEALRCGQGASLTVVKQNADVA 387
E EA R + + KQ +D A
Sbjct: 1122 EIEAERATRAKT---EKQRSDYA 1141
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 41.2 bits (95), Expect = 0.002
Identities = 44/183 (24%), Positives = 81/183 (44%), Gaps = 16/183 (8%)
Query: 243 SPAGSPSADFAVHGESLGDRHLRTLQIS--YDALKDENSKLRRKLNEVQSFSEAQTEMVR 300
SPA S S+ A+ +L R L+ + Y+A +D LR++L++ +S A E ++
Sbjct: 512 SPACSDSSTLALIHSALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQ 571
Query: 301 TLERKLEAKMIKEESDYHDLESVVQQVEQNLELMTKRAVK-------AENHVVKLKQEIS 353
L K + M E D + VQ++ EL+++ A+ +L+QE
Sbjct: 572 RLRDKTDGAMQAHE----DAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQERE 627
Query: 354 LLQAQVSNFQRENEALRCGQGASL---TVVKQNADVALQNLRVVMNSAQASIKQLVSGAE 410
LQA +R+ + L Q ++ V++ + + + L + K+LV E
Sbjct: 628 KLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVRE 687
Query: 411 TLN 413
L+
Sbjct: 688 ALS 690
Score = 38.9 bits (89), Expect = 0.009
Identities = 53/247 (21%), Positives = 98/247 (39%), Gaps = 24/247 (9%)
Query: 202 PAGTSPCSTYLSFFSTPSELAGPESLPSWALSDTDSRVSPASPAGSPSADFAVHGESLGD 261
PA +P ++PS L E P SPASP P A E L
Sbjct: 1461 PARDAPAEGSGEGLNSPSTL---ECSPGSQPPSPGPATSPASPDLDPEAVRGALREFL-- 1515
Query: 262 RHLRTLQISYDALKDENSKLRRKLNEVQSFSEAQTEMVRTLERKLEAKMIKEESDYHDLE 321
+ LR+ Q D L+ + S L R+L E+ EA+ + + R+L+ + + E ++
Sbjct: 1516 QELRSAQRERDELRTQTSALNRQLAEM----EAERDSATSRARQLQKAVAESEEARRSVD 1571
Query: 322 SVVQQVEQNLELMTKRAVKAE-------NHVVKLKQEISLLQAQVSNFQ------RENEA 368
+ V+ L L + ++E + V L++ + ++++ Q + NE
Sbjct: 1572 GRLSGVQAELALQEESVRRSERERRATLDQVATLERSLQATESELRASQEKISKMKANET 1631
Query: 369 LRCGQGASLTVVKQNADVALQNLRVVMNSAQASIKQLVSGAETLNLVAEILKSIDRISEV 428
G L V ++ L + S + +++ G A+ L+ DR+ +
Sbjct: 1632 KLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDREAQAQALQ--DRVDSL 1689
Query: 429 KDEEEDS 435
+ + DS
Sbjct: 1690 QRQVADS 1696
Score = 34.7 bits (78), Expect = 0.17
Identities = 52/244 (21%), Positives = 94/244 (38%), Gaps = 49/244 (20%)
Query: 176 EEEDEDTGWSGAYLPSAIEQTHPERVPAGTSPCSTYLSFFSTPSELAGPESLPSWALSDT 235
EEE ED GA + +E++H + +L G S+ + L +
Sbjct: 644 EEEQEDAVQDGARVRRELERSHRQL------------------EQLEGKRSVLAKELVEV 685
Query: 236 DSRVSPAS-PAGSPSADFAVHGESL--GDRHLRTLQISYDALKDENSKLRRKLNEVQSFS 292
+S A+ A+ A E+L + L++S L+ E + L+ L+++ + +
Sbjct: 686 REALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALN 745
Query: 293 EAQTEMVRTLERKLEAKMIKEESDYHDLESVVQQVEQNLELMTKRAVKAENHVVKLKQEI 352
E+ + D DL +V Q+E+ + R +AE ++E
Sbjct: 746 ESLAQ------------------DKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREE- 786
Query: 353 SLLQAQVSNFQRENEALRCGQGASLTVVKQNADVALQNL------RVVMNSAQASIKQLV 406
Q ++ + E E R G SL V +Q + Q L R + A + + +
Sbjct: 787 ---QERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQL 843
Query: 407 SGAE 410
SG E
Sbjct: 844 SGRE 847
Score = 33.9 bits (76), Expect = 0.30
Identities = 39/149 (26%), Positives = 69/149 (46%), Gaps = 17/149 (11%)
Query: 274 LKDENSKLRRKLNEVQSFSEAQTEMVRTLERK---LEAKMIKEESDYHDLESVVQQVEQN 330
L++ R+ L+E + S + E V+TL + LE + ++ E L V++Q ++
Sbjct: 1766 LQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEG 1825
Query: 331 LELMTKRAVKAENHVVKLKQEISLLQAQVSNFQRENEALRCGQGASLTVVKQNADVALQN 390
A N V KL+ E LLQ ++ + QR L A V+++A + L+
Sbjct: 1826 -------EAAALNTVQKLQDERRLLQERLGSLQRALAQLE----AEKREVERSA-LRLEK 1873
Query: 391 LRVVMNSAQASI--KQLVSGAETLNLVAE 417
RV + + ++L S +T+ L AE
Sbjct: 1874 DRVALRRTLDKVEREKLRSHEDTVRLSAE 1902
Score = 33.5 bits (75), Expect = 0.39
Identities = 49/196 (25%), Positives = 86/196 (43%), Gaps = 14/196 (7%)
Query: 232 LSDTDSRVSPASPAGSPSADFAVHGESLGDRHLRTLQISYDALKDENSKLR-RKLNEVQS 290
LS T R AS S S A++ ESL L L L++E S L+ R+ Q
Sbjct: 722 LSMTKLRAEEASLQDSLSKLSALN-ESLAQDKL-DLNRLVAQLEEEKSALQGRQRQAEQE 779
Query: 291 FSEAQTEMVRTLERKLEAKMIKE--ESDYHDLESVVQQVEQNLELMTKRAVKAENHVVKL 348
+ A+ E R E +LE ++ ++ E E + +EQ L + + + + +L
Sbjct: 780 ATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQL 839
Query: 349 KQEISLLQAQVS----NFQRENEALRCGQGASLTVVKQNADVALQNLRVVMNSAQASIKQ 404
+++S + ++ QR+ EAL + K++A +A+Q + +A+ +
Sbjct: 840 SRQLSGREQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQ-----LVAAEREGRT 894
Query: 405 LVSGAETLNLVAEILK 420
L A L L E L+
Sbjct: 895 LSEEATRLRLEKEALE 910
>gi|42794779 myosin 18A isoform b [Homo sapiens]
Length = 2039
Score = 41.2 bits (95), Expect = 0.002
Identities = 44/184 (23%), Positives = 80/184 (43%), Gaps = 16/184 (8%)
Query: 264 LRTLQISYDALKDENSKLRRKLNEVQSFSE------AQTEMVRTLE---RKLEAKMIKEE 314
+ LQ + E +L+ KL +QS E +V E R+LE ++ E
Sbjct: 1776 INDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFER 1835
Query: 315 SDYHDLESVVQQVEQNLELMTK---RAVKAENHVVKLKQEISLLQAQVSNFQRENEALRC 371
+ LES+ ++++N+E +T+ + + AEN + K++ LQ Q+ + + E L
Sbjct: 1836 TQVKRLESLASRLKENMEKLTEERDQRIAAEN---REKEQNKRLQRQLRDTKEEMGEL-A 1891
Query: 372 GQGASLTVVKQNADVALQNLRVVMNSAQASIKQLVSGAETLNLVAEILKSIDRISEVKDE 431
+ A + K ++ L++L S QA +K L E D ++ +
Sbjct: 1892 RKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIEDEMESDENEDLINS 1951
Query: 432 EEDS 435
E DS
Sbjct: 1952 EGDS 1955
Score = 32.7 bits (73), Expect = 0.66
Identities = 19/104 (18%), Positives = 56/104 (53%), Gaps = 1/104 (0%)
Query: 262 RHLRTLQISYDALKDENSKLRRKLNEVQSFSEAQTEMVRTLERKLEAKMIKEESDYHDLE 321
R L +Q+S + +++++ ++++ ++++ + + E+ R +LE+++ + S+ D
Sbjct: 1244 RPLIEVQLSEEQIRNKDEEIQQLRSKLEKAEKERNEL-RLNSDRLESRISELTSELTDER 1302
Query: 322 SVVQQVEQNLELMTKRAVKAENHVVKLKQEISLLQAQVSNFQRE 365
+ + Q L+ T ++AE + +L+ + L+ Q+ + E
Sbjct: 1303 NTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEME 1346
Score = 30.4 bits (67), Expect = 3.3
Identities = 25/100 (25%), Positives = 46/100 (46%), Gaps = 10/100 (10%)
Query: 267 LQISYDALKDENSKLRRKLNE----VQSFS------EAQTEMVRTLERKLEAKMIKEESD 316
LQ D L E L+++L E + F+ EA+ + + + E K EA + K +
Sbjct: 1484 LQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQ 1543
Query: 317 YHDLESVVQQVEQNLELMTKRAVKAENHVVKLKQEISLLQ 356
DLE+ V+ E+ L+ E ++L+ E+ ++
Sbjct: 1544 LRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMR 1583
>gi|23503243 Ras association (RalGDS/AF-6) domain family
(N-terminal) member 8 [Homo sapiens]
Length = 392
Score = 41.2 bits (95), Expect = 0.002
Identities = 23/124 (18%), Positives = 65/124 (52%), Gaps = 5/124 (4%)
Query: 251 DFAVHGESLGDRHLRTLQISYDALKDENSKLRRKLNEVQSFSEAQTEMVRTLERKLEAKM 310
D + E + L+ Q + LKD+ ++R+K+ E ++ + +RT+E LEA+
Sbjct: 217 DVEIEEEEFWENELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEK 276
Query: 311 IKEE-----SDYHDLESVVQQVEQNLELMTKRAVKAENHVVKLKQEISLLQAQVSNFQRE 365
++ E + +++ + +V+ +++ +++++ EN + +++ + ++ + ++E
Sbjct: 277 LQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQE 336
Query: 366 NEAL 369
E L
Sbjct: 337 LEQL 340
>gi|13540600 nudE nuclear distribution gene E homolog (A.
nidulans)-like 1 isoform B [Homo sapiens]
Length = 345
Score = 40.8 bits (94), Expect = 0.002
Identities = 29/106 (27%), Positives = 58/106 (54%), Gaps = 10/106 (9%)
Query: 271 YDALKDENSKLRR-KLNEVQSFSEAQTEMV------RTLERKLEAKMIKEESDYHDLESV 323
+ +LK+E + + L QSF EA+ E+V R LE +LEA++++ E DL++
Sbjct: 9 FSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQAD 68
Query: 324 VQQVEQNLELMTKRAVKAENHVVKLKQEISLLQAQVSNFQRENEAL 369
Q+++ +E + + K E+ + +++S+L+ +S + E L
Sbjct: 69 NQRLKYEVEALKE---KLEHQYAQSYKQVSVLEDDLSQTRAIKEQL 111
>gi|71284108 nudE nuclear distribution gene E homolog (A.
nidulans)-like 1 isoform A [Homo sapiens]
Length = 328
Score = 40.8 bits (94), Expect = 0.002
Identities = 29/106 (27%), Positives = 58/106 (54%), Gaps = 10/106 (9%)
Query: 271 YDALKDENSKLRR-KLNEVQSFSEAQTEMV------RTLERKLEAKMIKEESDYHDLESV 323
+ +LK+E + + L QSF EA+ E+V R LE +LEA++++ E DL++
Sbjct: 9 FSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQAD 68
Query: 324 VQQVEQNLELMTKRAVKAENHVVKLKQEISLLQAQVSNFQRENEAL 369
Q+++ +E + + K E+ + +++S+L+ +S + E L
Sbjct: 69 NQRLKYEVEALKE---KLEHQYAQSYKQVSVLEDDLSQTRAIKEQL 111
>gi|224586823 coiled-coil domain containing 110 isoform b [Homo
sapiens]
Length = 796
Score = 40.8 bits (94), Expect = 0.002
Identities = 25/91 (27%), Positives = 50/91 (54%), Gaps = 4/91 (4%)
Query: 275 KDENSKLRRKLNEVQSFSEAQTEMVRTLERKLEAKMIKEESDYHDLESVVQQVEQNLELM 334
K E S + L+E+ E ++MV +E K + +++KEE H E++ + E ++ +
Sbjct: 647 KSEASIYKNSLSEIGKECEMLSKMV--METKTDNQILKEELKKHSQENI--KFENSISRL 702
Query: 335 TKRAVKAENHVVKLKQEISLLQAQVSNFQRE 365
T+ + EN+V ++ E L+ ++ + QRE
Sbjct: 703 TEDKILLENYVRSIENERDTLEFEMRHLQRE 733
>gi|22749515 coiled-coil domain containing 110 isoform a [Homo
sapiens]
Length = 833
Score = 40.8 bits (94), Expect = 0.002
Identities = 25/91 (27%), Positives = 50/91 (54%), Gaps = 4/91 (4%)
Query: 275 KDENSKLRRKLNEVQSFSEAQTEMVRTLERKLEAKMIKEESDYHDLESVVQQVEQNLELM 334
K E S + L+E+ E ++MV +E K + +++KEE H E++ + E ++ +
Sbjct: 684 KSEASIYKNSLSEIGKECEMLSKMV--METKTDNQILKEELKKHSQENI--KFENSISRL 739
Query: 335 TKRAVKAENHVVKLKQEISLLQAQVSNFQRE 365
T+ + EN+V ++ E L+ ++ + QRE
Sbjct: 740 TEDKILLENYVRSIENERDTLEFEMRHLQRE 770
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.129 0.369
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,774,896
Number of Sequences: 37866
Number of extensions: 945404
Number of successful extensions: 3865
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 116
Number of HSP's successfully gapped in prelim test: 371
Number of HSP's that attempted gapping in prelim test: 3082
Number of HSP's gapped (non-prelim): 1125
length of query: 435
length of database: 18,247,518
effective HSP length: 105
effective length of query: 330
effective length of database: 14,271,588
effective search space: 4709624040
effective search space used: 4709624040
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.