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Search of human proteins with 8922301
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|8922301 WD repeat domain 70 [Homo sapiens]
(654 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|8922301 WD repeat domain 70 [Homo sapiens] 1338 0.0
gi|16554629 WD repeat domain 5 [Homo sapiens] 63 7e-10
gi|16554627 WD repeat domain 5 [Homo sapiens] 63 7e-10
gi|32189425 WD repeat domain 69 [Homo sapiens] 62 2e-09
gi|237820620 glutamate-rich WD repeat containing 1 [Homo sapiens] 60 6e-09
gi|83779014 katanin p80 subunit B 1 [Homo sapiens] 59 1e-08
gi|115298668 WD repeat domain 57 (U5 snRNP specific) [Homo sapiens] 59 2e-08
gi|26665869 WD repeat domain 51B [Homo sapiens] 59 2e-08
gi|32483361 apoptotic peptidase activating factor 1 isoform d [H... 57 7e-08
gi|4502123 apoptotic peptidase activating factor 1 isoform b [Ho... 57 7e-08
gi|21536371 telomerase-associated protein 1 [Homo sapiens] 55 2e-07
gi|207029439 retinoblastoma binding protein 4 isoform c [Homo sa... 55 3e-07
gi|207029415 retinoblastoma binding protein 4 isoform b [Homo sa... 55 3e-07
gi|5032027 retinoblastoma binding protein 4 isoform a [Homo sapi... 55 3e-07
gi|124256480 APG16 autophagy 16-like isoform 1 [Homo sapiens] 55 3e-07
gi|124256478 APG16 autophagy 16-like isoform 2 [Homo sapiens] 55 3e-07
gi|4506439 retinoblastoma binding protein 7 [Homo sapiens] 54 5e-07
gi|55743075 angio-associated, migratory cell protein [Homo sapiens] 53 8e-07
gi|21071067 TBP-associated factor 5 [Homo sapiens] 52 2e-06
gi|210032580 SET domain containing 1B [Homo sapiens] 51 3e-06
gi|211904182 DDB1 and CUL4 associated factor 8-like 2 [Homo sapi... 51 4e-06
gi|7657439 PCAF associated factor 65 beta isoform a [Homo sapiens] 51 4e-06
gi|23199987 WD repeat domain 5B [Homo sapiens] 51 4e-06
gi|30089954 H326 [Homo sapiens] 51 4e-06
gi|109948304 smu-1 suppressor of mec-8 and unc-52 homolog [Homo ... 50 5e-06
gi|4505731 peroxisomal biogenesis factor 7 [Homo sapiens] 50 7e-06
gi|113865883 WD repeat domain 38 [Homo sapiens] 50 7e-06
gi|4557515 damage-specific DNA binding protein 2 [Homo sapiens] 49 1e-05
gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens] 49 1e-05
gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens] 49 1e-05
>gi|8922301 WD repeat domain 70 [Homo sapiens]
Length = 654
Score = 1338 bits (3464), Expect = 0.0
Identities = 654/654 (100%), Positives = 654/654 (100%)
Query: 1 MERSGPSEVTGSDASGPDPQLAVTMGFTGFGKKARTFDLEAMFEQTRRTAVERSRKTLEA 60
MERSGPSEVTGSDASGPDPQLAVTMGFTGFGKKARTFDLEAMFEQTRRTAVERSRKTLEA
Sbjct: 1 MERSGPSEVTGSDASGPDPQLAVTMGFTGFGKKARTFDLEAMFEQTRRTAVERSRKTLEA 60
Query: 61 REKEEEMNREKELRRQNEDIEPTSSRSNVVRDCSKSSSRDTSSSESEQSSDSSDDELIGP 120
REKEEEMNREKELRRQNEDIEPTSSRSNVVRDCSKSSSRDTSSSESEQSSDSSDDELIGP
Sbjct: 61 REKEEEMNREKELRRQNEDIEPTSSRSNVVRDCSKSSSRDTSSSESEQSSDSSDDELIGP 120
Query: 121 PLPPKMVGKPVNFMEEDILGPLPPPLNEEEEEAEEEEEEEEEEENPVHKIPDSHEITLKH 180
PLPPKMVGKPVNFMEEDILGPLPPPLNEEEEEAEEEEEEEEEEENPVHKIPDSHEITLKH
Sbjct: 121 PLPPKMVGKPVNFMEEDILGPLPPPLNEEEEEAEEEEEEEEEEENPVHKIPDSHEITLKH 180
Query: 181 GTKTVSALGLDPSGARLVTGGYDYDVKFWDFAGMDASFKAFRSLQPCECHQIKSLQYSNT 240
GTKTVSALGLDPSGARLVTGGYDYDVKFWDFAGMDASFKAFRSLQPCECHQIKSLQYSNT
Sbjct: 181 GTKTVSALGLDPSGARLVTGGYDYDVKFWDFAGMDASFKAFRSLQPCECHQIKSLQYSNT 240
Query: 241 GDMILVVSGSSQAKVIDRDGFEVMECIKGDQYIVDMANTKGHTAMLHTGSWHPKIKGEFM 300
GDMILVVSGSSQAKVIDRDGFEVMECIKGDQYIVDMANTKGHTAMLHTGSWHPKIKGEFM
Sbjct: 241 GDMILVVSGSSQAKVIDRDGFEVMECIKGDQYIVDMANTKGHTAMLHTGSWHPKIKGEFM 300
Query: 301 TCSNDATVRTWEVENPKKQKSVFKPRTMQGKKVIPTTCTYSRDGNLIAAACQNGSIQIWD 360
TCSNDATVRTWEVENPKKQKSVFKPRTMQGKKVIPTTCTYSRDGNLIAAACQNGSIQIWD
Sbjct: 301 TCSNDATVRTWEVENPKKQKSVFKPRTMQGKKVIPTTCTYSRDGNLIAAACQNGSIQIWD 360
Query: 361 RNLTVHPKFHYKQAHDSGTDTSCVTFSYDGNVLASRGGDDSLKLWDIRQFNKPLFSASGL 420
RNLTVHPKFHYKQAHDSGTDTSCVTFSYDGNVLASRGGDDSLKLWDIRQFNKPLFSASGL
Sbjct: 361 RNLTVHPKFHYKQAHDSGTDTSCVTFSYDGNVLASRGGDDSLKLWDIRQFNKPLFSASGL 420
Query: 421 PTMFPMTDCCFSPDDKLIVTGTSIQRGCGSGKLVFFERRTFQRVYEIDITDASVVRCLWH 480
PTMFPMTDCCFSPDDKLIVTGTSIQRGCGSGKLVFFERRTFQRVYEIDITDASVVRCLWH
Sbjct: 421 PTMFPMTDCCFSPDDKLIVTGTSIQRGCGSGKLVFFERRTFQRVYEIDITDASVVRCLWH 480
Query: 481 PKLNQIMVGTGNGLAKVYYDPNKSQRGAKLCVVKTQRKAKQAETLTQDYIITPHALPMFR 540
PKLNQIMVGTGNGLAKVYYDPNKSQRGAKLCVVKTQRKAKQAETLTQDYIITPHALPMFR
Sbjct: 481 PKLNQIMVGTGNGLAKVYYDPNKSQRGAKLCVVKTQRKAKQAETLTQDYIITPHALPMFR 540
Query: 541 EPRQRSTRKQLEKDRLDPLKSHKPEPPVAGPGRGGRVGTHGGTLSSYIVKNIALDKTDDS 600
EPRQRSTRKQLEKDRLDPLKSHKPEPPVAGPGRGGRVGTHGGTLSSYIVKNIALDKTDDS
Sbjct: 541 EPRQRSTRKQLEKDRLDPLKSHKPEPPVAGPGRGGRVGTHGGTLSSYIVKNIALDKTDDS 600
Query: 601 NPREAILRHAKAAEDSPYWVSPAYSKTQPKTMFAQVESDDEEAKNEPEWKKRKI 654
NPREAILRHAKAAEDSPYWVSPAYSKTQPKTMFAQVESDDEEAKNEPEWKKRKI
Sbjct: 601 NPREAILRHAKAAEDSPYWVSPAYSKTQPKTMFAQVESDDEEAKNEPEWKKRKI 654
>gi|16554629 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 63.2 bits (152), Expect = 7e-10
Identities = 56/232 (24%), Positives = 98/232 (42%), Gaps = 27/232 (11%)
Query: 175 EITLKHGTKTVSALGLDPSGARLVTGGYDYDVKFWDFAGMDASFKAFRSLQPCECHQIKS 234
+ TL TK VS++ P+G L + D +K W D F+ S I
Sbjct: 38 KFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIW--GAYDGKFEKTISGHKL---GISD 92
Query: 235 LQYSNTGDMILVVSGSSQAKVIDRDGFEVMECIKGDQYIVDMANTKGHTAMLHTGSWHPK 294
+ +S+ ++++ S K+ D + ++ +KG V N + ++ +GS+
Sbjct: 93 VAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSF--- 149
Query: 295 IKGEFMTCSNDATVRTWEVENPKKQKSVFKPRTMQGKKVIPTTCTYSRDGNLIAAACQNG 354
D +VR W+V+ K K T+ + ++RDG+LI ++ +G
Sbjct: 150 ----------DESVRIWDVKTGKCLK------TLPAHSDPVSAVHFNRDGSLIVSSSYDG 193
Query: 355 SIQIWDRNLTVHPKFHYKQAHDSGTDTSCVTFSYDGNVLASRGGDDSLKLWD 406
+IWD T + D S V FS +G + + D++LKLWD
Sbjct: 194 LCRIWD---TASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWD 242
Score = 48.1 bits (113), Expect = 2e-05
Identities = 32/129 (24%), Positives = 61/129 (47%), Gaps = 13/129 (10%)
Query: 281 GHTAMLHTGSWHPKIKGEFMTCSN-DATVRTWEVENPKKQKSVFKPRTMQGKKVIPTTCT 339
GHT + + + P GE++ S+ D ++ W + K +K T+ G K+ +
Sbjct: 43 GHTKAVSSVKFSPN--GEWLASSSADKLIKIWGAYDGKFEK------TISGHKLGISDVA 94
Query: 340 YSRDGNLIAAACQNGSIQIWDRNLTVHPKFHYKQAHDSGTDTSCVTFSYDGNVLASRGGD 399
+S D NL+ +A + +++IWD V K C F+ N++ S D
Sbjct: 95 WSSDSNLLVSASDDKTLKIWD----VSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFD 150
Query: 400 DSLKLWDIR 408
+S+++WD++
Sbjct: 151 ESVRIWDVK 159
Score = 39.7 bits (91), Expect = 0.009
Identities = 33/116 (28%), Positives = 53/116 (45%), Gaps = 7/116 (6%)
Query: 327 TMQGKKVIPTTCTYSRDGNLIAAACQNGSIQIWDRNLTVHPKFHYKQAHDSGTDTSCVTF 386
T+ G ++ +S +G +A++ + I+IW KF K S V +
Sbjct: 40 TLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWG---AYDGKFE-KTISGHKLGISDVAW 95
Query: 387 SYDGNVLASRGGDDSLKLWDIRQFNKPLFSASGLPTMFPMTDCCFSPDDKLIVTGT 442
S D N+L S D +LK+WD+ K L + G + C F+P LIV+G+
Sbjct: 96 SSDSNLLVSASDDKTLKIWDVSS-GKCLKTLKGHSNY--VFCCNFNPQSNLIVSGS 148
Score = 32.0 bits (71), Expect = 1.8
Identities = 48/236 (20%), Positives = 88/236 (37%), Gaps = 36/236 (15%)
Query: 177 TLKHGTKTVSALGLDPSGARLVTGGYDYDVKFWDFAGMDASFKAFRSLQPCECHQIKSLQ 236
TLK + V +P +V+G +D V+ WD + K ++L P + ++
Sbjct: 124 TLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDV----KTGKCLKTL-PAHSDPVSAVH 178
Query: 237 YSNTGDMILVVSGSSQAKVIDRDGFEVMECIKGDQYIVDMANTKGHTAMLHTGSWHPKIK 296
++ G +I+ S ++ D + ++ + D + + P K
Sbjct: 179 FNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDD-----------NPPVSFVKFSPNGK 227
Query: 297 GEFMTCSNDATVRTWEVENPKKQKSVFKPRTMQGKKVIPTTCTYSR----DGNLIAAACQ 352
+ + D T++ W+ K K T G K C ++ G I + +
Sbjct: 228 -YILAATLDNTLKLWDYSKGKCLK------TYTGHK-NEKYCIFANFSVTGGKWIVSGSE 279
Query: 353 NGSIQIWDRNLTVHPKFHYKQAH-DSGTDTSCVTFSYDGNVLASRG--GDDSLKLW 405
+ + IW NL Q H D T+C N++AS D ++KLW
Sbjct: 280 DNLVYIW--NLQTKEIVQKLQGHTDVVISTACHPTE---NIIASAALENDKTIKLW 330
>gi|16554627 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 63.2 bits (152), Expect = 7e-10
Identities = 56/232 (24%), Positives = 98/232 (42%), Gaps = 27/232 (11%)
Query: 175 EITLKHGTKTVSALGLDPSGARLVTGGYDYDVKFWDFAGMDASFKAFRSLQPCECHQIKS 234
+ TL TK VS++ P+G L + D +K W D F+ S I
Sbjct: 38 KFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIW--GAYDGKFEKTISGHKL---GISD 92
Query: 235 LQYSNTGDMILVVSGSSQAKVIDRDGFEVMECIKGDQYIVDMANTKGHTAMLHTGSWHPK 294
+ +S+ ++++ S K+ D + ++ +KG V N + ++ +GS+
Sbjct: 93 VAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSF--- 149
Query: 295 IKGEFMTCSNDATVRTWEVENPKKQKSVFKPRTMQGKKVIPTTCTYSRDGNLIAAACQNG 354
D +VR W+V+ K K T+ + ++RDG+LI ++ +G
Sbjct: 150 ----------DESVRIWDVKTGKCLK------TLPAHSDPVSAVHFNRDGSLIVSSSYDG 193
Query: 355 SIQIWDRNLTVHPKFHYKQAHDSGTDTSCVTFSYDGNVLASRGGDDSLKLWD 406
+IWD T + D S V FS +G + + D++LKLWD
Sbjct: 194 LCRIWD---TASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWD 242
Score = 48.1 bits (113), Expect = 2e-05
Identities = 32/129 (24%), Positives = 61/129 (47%), Gaps = 13/129 (10%)
Query: 281 GHTAMLHTGSWHPKIKGEFMTCSN-DATVRTWEVENPKKQKSVFKPRTMQGKKVIPTTCT 339
GHT + + + P GE++ S+ D ++ W + K +K T+ G K+ +
Sbjct: 43 GHTKAVSSVKFSPN--GEWLASSSADKLIKIWGAYDGKFEK------TISGHKLGISDVA 94
Query: 340 YSRDGNLIAAACQNGSIQIWDRNLTVHPKFHYKQAHDSGTDTSCVTFSYDGNVLASRGGD 399
+S D NL+ +A + +++IWD V K C F+ N++ S D
Sbjct: 95 WSSDSNLLVSASDDKTLKIWD----VSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFD 150
Query: 400 DSLKLWDIR 408
+S+++WD++
Sbjct: 151 ESVRIWDVK 159
Score = 39.7 bits (91), Expect = 0.009
Identities = 33/116 (28%), Positives = 53/116 (45%), Gaps = 7/116 (6%)
Query: 327 TMQGKKVIPTTCTYSRDGNLIAAACQNGSIQIWDRNLTVHPKFHYKQAHDSGTDTSCVTF 386
T+ G ++ +S +G +A++ + I+IW KF K S V +
Sbjct: 40 TLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWG---AYDGKFE-KTISGHKLGISDVAW 95
Query: 387 SYDGNVLASRGGDDSLKLWDIRQFNKPLFSASGLPTMFPMTDCCFSPDDKLIVTGT 442
S D N+L S D +LK+WD+ K L + G + C F+P LIV+G+
Sbjct: 96 SSDSNLLVSASDDKTLKIWDVSS-GKCLKTLKGHSNY--VFCCNFNPQSNLIVSGS 148
Score = 32.0 bits (71), Expect = 1.8
Identities = 48/236 (20%), Positives = 88/236 (37%), Gaps = 36/236 (15%)
Query: 177 TLKHGTKTVSALGLDPSGARLVTGGYDYDVKFWDFAGMDASFKAFRSLQPCECHQIKSLQ 236
TLK + V +P +V+G +D V+ WD + K ++L P + ++
Sbjct: 124 TLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDV----KTGKCLKTL-PAHSDPVSAVH 178
Query: 237 YSNTGDMILVVSGSSQAKVIDRDGFEVMECIKGDQYIVDMANTKGHTAMLHTGSWHPKIK 296
++ G +I+ S ++ D + ++ + D + + P K
Sbjct: 179 FNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDD-----------NPPVSFVKFSPNGK 227
Query: 297 GEFMTCSNDATVRTWEVENPKKQKSVFKPRTMQGKKVIPTTCTYSR----DGNLIAAACQ 352
+ + D T++ W+ K K T G K C ++ G I + +
Sbjct: 228 -YILAATLDNTLKLWDYSKGKCLK------TYTGHK-NEKYCIFANFSVTGGKWIVSGSE 279
Query: 353 NGSIQIWDRNLTVHPKFHYKQAH-DSGTDTSCVTFSYDGNVLASRG--GDDSLKLW 405
+ + IW NL Q H D T+C N++AS D ++KLW
Sbjct: 280 DNLVYIW--NLQTKEIVQKLQGHTDVVISTACHPTE---NIIASAALENDKTIKLW 330
>gi|32189425 WD repeat domain 69 [Homo sapiens]
Length = 415
Score = 62.0 bits (149), Expect = 2e-09
Identities = 68/324 (20%), Positives = 141/324 (43%), Gaps = 42/324 (12%)
Query: 178 LKHGTKTVSALGLDPSGARLVTGGYDYDVKFWDFAGMDASFKAFRSLQPCECHQ--IKSL 235
LK ++ + L+ SG+ +TG YD K WD A + L E H+ + ++
Sbjct: 88 LKAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGE-------ELNTLEGHRNVVYAI 140
Query: 236 QYSNT-GDMILVVSGSSQAKVIDRDGFEVMECIKGDQYIVDMANTKGHTAMLHTGSWHPK 294
++N GD I S K+ E +C +GHTA + S++P+
Sbjct: 141 AFNNPYGDKIATGSFDKTCKLW---SVETGKCYH---------TFRGHTAEIVCLSFNPQ 188
Query: 295 IKGEFMTCSNDATVRTWEVENPKKQKSVFKPRTMQGKKVIPTTCTYSRDGNLIAAACQNG 354
T S D T + W+++N + + T++G + +++ G+ I +
Sbjct: 189 -STLVATGSMDTTAKLWDIQNGE------EVYTLRGHSAEIISLSFNTSGDRIITGSFDH 241
Query: 355 SIQIWDRNLTVHPKFHYKQAHDSGTDTSCVTFSYDGNVLASRGGDDSLKLWDIRQFNKPL 414
++ +WD + K + H + + S +F++D +++ + D + KLWD K +
Sbjct: 242 TVVVWDAD--TGRKVNILIGHCA--EISSASFNWDCSLILTGSMDKTCKLWDATN-GKCV 296
Query: 415 FSASGLPTMFPMTDCCFSPDDKLIVTGTSIQRGCGSGKLVFFERRTFQRVYEIDITDASV 474
+ +G + D CF KLI T ++ G F T + + +++ + +
Sbjct: 297 ATLTGHDD--EILDSCFDYTGKLIATASA------DGTARIFSAATRKCIAKLEGHEGEI 348
Query: 475 VRCLWHPKLNQIMVGTGNGLAKVY 498
+ ++P+ N ++ G+ + A+++
Sbjct: 349 SKISFNPQGNHLLTGSSDKTARIW 372
Score = 49.7 bits (117), Expect = 9e-06
Identities = 56/270 (20%), Positives = 106/270 (39%), Gaps = 39/270 (14%)
Query: 177 TLKHGTKTVSALGLDPSGARLVTGGYDYDVKFWDFAGMDASFKAFRSLQPCECHQIKSLQ 236
T + T + L +P + TG D K WD + + R +I SL
Sbjct: 172 TFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVY-TLRG----HSAEIISLS 226
Query: 237 YSNTGDMILVVSGSSQAKVIDRDGFEVMECIKGDQYIVDMANTKGHTAMLHTGSWHPKIK 296
++ +GD I+ S V D D + + G + A+ +++ TGS
Sbjct: 227 FNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISSASFNWDCSLILTGSM----- 281
Query: 297 GEFMTCSNDATVRTWEVENPKKQKSVFKPRTMQGKKVIPTTCTYSRDGNLIAAACQNGSI 356
D T + W+ N K ++ T +++ + Y+ G LIA A +G+
Sbjct: 282 --------DKTCKLWDATNGKCVATL----TGHDDEILDSCFDYT--GKLIATASADGTA 327
Query: 357 QIWDRNLTVHPKFHYKQAHDSGTDTSCVTFSYDGNVLASRGGDDSLKLWDIRQFNKPLFS 416
+I+ + + H+ + S ++F+ GN L + D + ++WD + +
Sbjct: 328 RIF--SAATRKCIAKLEGHEG--EISKISFNPQGNHLLTGSSDKTARIWDAQ-------T 376
Query: 417 ASGLPTMFPMTD----CCFSPDDKLIVTGT 442
L + TD C F+ +++TG+
Sbjct: 377 GQCLQVLEGHTDEIFSCAFNYKGNIVITGS 406
Score = 46.2 bits (108), Expect = 9e-05
Identities = 52/232 (22%), Positives = 97/232 (41%), Gaps = 34/232 (14%)
Query: 177 TLKHGTKTVSALGLDPSGARLVTGGYDYDVKFWDFAGMDASFKAFRSLQPCECHQIKSLQ 236
TL+ + + +L + SG R++TG +D+ V WD D K ++ C +I S
Sbjct: 214 TLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWD---ADTGRKV--NILIGHCAEISSAS 268
Query: 237 YSNTGDMILVVSGSSQAKVIDRDGFEVMECIKG-DQYIVDMANTKGHTAMLHTGSWHPKI 295
++ +IL S K+ D + + + G D I+D + +TG
Sbjct: 269 FNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILD-------SCFDYTGKL---- 317
Query: 296 KGEFMTCSNDATVRTWEVENPKKQKSVFKPRTMQGKKVIPTTCTYSRDGNLIAAACQNGS 355
T S D T R + +K + K ++G + + +++ GN + + +
Sbjct: 318 ---IATASADGTARIFSAAT---RKCIAK---LEGHEGEISKISFNPQGNHLLTGSSDKT 368
Query: 356 IQIWDRNLTVHPKFHYKQAHDSGTDT--SCVTFSYDGNVLASRGGDDSLKLW 405
+IWD Q + TD SC F+Y GN++ + D++ ++W
Sbjct: 369 ARIWDAQTG-----QCLQVLEGHTDEIFSC-AFNYKGNIVITGSKDNTCRIW 414
>gi|237820620 glutamate-rich WD repeat containing 1 [Homo sapiens]
Length = 446
Score = 60.1 bits (144), Expect = 6e-09
Identities = 74/291 (25%), Positives = 110/291 (37%), Gaps = 43/291 (14%)
Query: 140 GPLPPPLNEEEEEAEEEEEEEEEEENP---VHKIPDSHEITLKHGTKTVSALGLDPSGAR 196
G PPP +EE EEE+EE+EEE P + +P I VS LG +P
Sbjct: 113 GTKPPPSEGSDEEEEEEDEEDEEERKPQLELAMVPHYGGINRVR----VSWLGEEP---- 164
Query: 197 LVTGGYDYDVKFWDFAGMDASFKAFRSLQPCECHQ-----IKSLQ------YSNTGDM-- 243
V G W G F R LQ E Q ++ Q +S G M
Sbjct: 165 -VAG-------VWSEKGQVEVFALRRLLQVVEEPQALAAFLRDEQAQMKPIFSFAGHMGE 216
Query: 244 --ILVVSGSSQAKVIDRD---GFEVMECIKGDQYIVDMANTKGHTAMLHTGSWHPKIKGE 298
L S +++ D + G + VD GHT + W P
Sbjct: 217 GFALDWSPRVTGRLLTGDCQKNIHLWTPTDGGSWHVDQRPFVGHTRSVEDLQWSPTENTV 276
Query: 299 FMTCSNDATVRTWEVENPKKQKSVFKPRTMQGKKVIPTTCTYSRDGNLIAAACQNGSIQI 358
F +CS DA++R W++ + + T V ++SR + + +G+++I
Sbjct: 277 FASCSADASIRIWDIRAAPSKACMLTTATAHDGDV--NVISWSRREPFLLSGGDDGALKI 334
Query: 359 WD--RNLTVHPKFHYKQAHDSGTDTSCVTFSYDGNVLASRGGDDSLKLWDI 407
WD + + P +KQ TS D V A+ G D + WD+
Sbjct: 335 WDLRQFKSGSPVATFKQ--HVAPVTSVEWHPQDSGVFAASGADHQITQWDL 383
>gi|83779014 katanin p80 subunit B 1 [Homo sapiens]
Length = 655
Score = 58.9 bits (141), Expect = 1e-08
Identities = 59/263 (22%), Positives = 110/263 (41%), Gaps = 33/263 (12%)
Query: 180 HGTKTVSALGLDPSGARLVTGGYDYDVKFWDFAGMDASFKAFRSLQPCECHQIKSLQYSN 239
H + S + SG L TGG D V W + P ++S++ +
Sbjct: 19 HASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSP-----VESVRLNT 73
Query: 240 TGDMILVVSGSSQAKVIDRDGFEVMECIKGDQYIVDMANTKGHTAMLHTGSWHPKIKGEF 299
++I+ S S +V D + +++ + GH A + + +HP GEF
Sbjct: 74 PEELIVAGSQSGSIRVWDLEAAKILRTL------------MGHKANICSLDFHP--YGEF 119
Query: 300 MTC-SNDATVRTWEVENPKKQKSVFKPRTMQGKKVIPTTCTYSRDGNLIAAACQNGSIQI 358
+ S D ++ W++ +++ VF+ R G +S DG +A+A + ++++
Sbjct: 120 VASGSQDTNIKLWDI---RRKGCVFRYR---GHSQAVRCLRFSPDGKWLASAADDHTVKL 173
Query: 359 WDRNLTVHPKFHYKQAHDSGTDTSCVTFSYDGNVLASRGGDDSLKLWDIRQFNKPLFSAS 418
WD LT H + V F + +LAS D +++ WD+ +F + +
Sbjct: 174 WD--LTAGKMMSEFPGHTG--PVNVVEFHPNEYLLASGSSDRTIRFWDLEKF-QVVSCIE 228
Query: 419 GLPTMFPMTDCCFSPDDKLIVTG 441
G P P+ F+PD + +G
Sbjct: 229 GEPG--PVRSVLFNPDGCCLYSG 249
Score = 49.7 bits (117), Expect = 9e-06
Identities = 48/201 (23%), Positives = 85/201 (42%), Gaps = 19/201 (9%)
Query: 303 SNDATVRTWEVENPKKQKSVFKPRTMQGKKVIPTTCTYSRDGNLIAAACQNGSIQIWDRN 362
S ++R W++E K RT+ G K + + G +A+ Q+ +I++WD
Sbjct: 82 SQSGSIRVWDLEAAKIL------RTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWD-- 133
Query: 363 LTVHPKFHYKQAHDSGTDTSCVTFSYDGNVLASRGGDDSLKLWDIRQFNKPLFSASGLPT 422
+ K + C+ FS DG LAS D ++KLWD+ K + G
Sbjct: 134 --IRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTA-GKMMSEFPG--H 188
Query: 423 MFPMTDCCFSPDDKLIVTGTSIQRGCGSGKLVFFERRTFQRVYEIDITDASVVRCLWHPK 482
P+ F P++ L+ +G+S + F++ FQ V I+ V L++P
Sbjct: 189 TGPVNVVEFHPNEYLLASGSS------DRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPD 242
Query: 483 LNQIMVGTGNGLAKVYYDPNK 503
+ G + L ++P +
Sbjct: 243 GCCLYSGCQDSLRVYGWEPER 263
Score = 38.9 bits (89), Expect = 0.015
Identities = 36/179 (20%), Positives = 70/179 (39%), Gaps = 28/179 (15%)
Query: 177 TLKHGTKTVSALGLDPSGARLVTGGYDYDVKFWDFAGMDASFKAFRSLQPCECHQIKSLQ 236
TL + +L P G + +G D ++K WD F+ Q C L+
Sbjct: 100 TLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRC-----LR 154
Query: 237 YSNTGDMILVVSGSSQAKVIDRDGFEVMECIKGDQYIVDMANTKGHTAMLHTGSWHPKIK 296
+S G + + K+ D ++ M+ GHT ++ +HP
Sbjct: 155 FSPDGKWLASAADDHTVKLWDLTAGKM------------MSEFPGHTGPVNVVEFHP--- 199
Query: 297 GEFMTC--SNDATVRTWEVENPKKQKSVFKPRTMQGKKVIPTTCTYSRDGNLIAAACQN 353
E++ S+D T+R W++E + + +G+ + ++ DG + + CQ+
Sbjct: 200 NEYLLASGSSDRTIRFWDLEKFQVVSCI------EGEPGPVRSVLFNPDGCCLYSGCQD 252
>gi|115298668 WD repeat domain 57 (U5 snRNP specific) [Homo sapiens]
Length = 357
Score = 58.5 bits (140), Expect = 2e-08
Identities = 62/298 (20%), Positives = 126/298 (42%), Gaps = 44/298 (14%)
Query: 192 PSGARLVTGGYDYDVKFWDFAGMDASFKAFRSLQPCECHQIKSLQYSNTGDMILVVSGSS 251
P+G+ L + G+D + W+ G ++ + + L Y+ G M+ S
Sbjct: 76 PNGSTLASAGFDRLILLWNVYGDCDNYATLKG----HSGAVMELHYNTDGSMLFSASTDK 131
Query: 252 QAKVIDRDGFEVMECIKGDQYIVDMANTKGHTAMLHTGSWHPKIKGEFMTC--SNDATVR 309
V D + E ++ KGHT+ ++ S +P +G + C S+D TV+
Sbjct: 132 TVAVWDSETGERVK------------RLKGHTSFVN--SCYPARRGPQLVCTGSDDGTVK 177
Query: 310 TWEVENPKKQKSVFKPRTMQGKKVIPTTCTYSRDGNLIAAACQNGSIQIWDRNLTVHPKF 369
W++ +K+ ++ +T Q + T++ + I + + I++WD K
Sbjct: 178 LWDI---RKKAAI---QTFQNTYQV-LAVTFNDTSDQIISGGIDNDIKVWDLR---QNKL 227
Query: 370 HYKQAHDSGTDTSCVTFSYDGNVLASRGGDDSLKLWDIRQFNK-----PLFSASGLPTMF 424
Y + + T ++ S +G+ L S D+++++WD+R F +F +
Sbjct: 228 TYTMRGHADSVTG-LSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEK 286
Query: 425 PMTDCCFSPDDKLIVTGTSIQRGCGSGKLVFFERRTFQRV-YEIDITDASVVRCLWHP 481
+ C +SPD I G+ + + V+ T +R+ Y++ S+ +HP
Sbjct: 287 NLLRCSWSPDGSKIAAGS-------ADRFVYVWDTTSRRILYKLPGHAGSINEVAFHP 337
Score = 47.4 bits (111), Expect = 4e-05
Identities = 47/226 (20%), Positives = 95/226 (42%), Gaps = 20/226 (8%)
Query: 277 ANTKGHTAMLHTGSWHPKIKGEFM-TCSNDATVRTWEVENPKKQKSVFKPRTMQGKKVIP 335
A KGH+ + H G + + S D TV W+ E ++ K ++G
Sbjct: 103 ATLKGHSGAVM--ELHYNTDGSMLFSASTDKTVAVWDSETGERVKR------LKGHTSFV 154
Query: 336 TTCTYSRDG-NLIAAACQNGSIQIWDRNLTVHPKFHYKQAHDSGTDTSCVTFSYDGNVLA 394
+C +R G L+ +G++++WD K Q + VTF+ + +
Sbjct: 155 NSCYPARRGPQLVCTGSDDGTVKLWDIR-----KKAAIQTFQNTYQVLAVTFNDTSDQII 209
Query: 395 SRGGDDSLKLWDIRQFNKPLFSASGLPTMFPMTDCCFSPDDKLIVTGTSIQRGCGSGKLV 454
S G D+ +K+WD+RQ NK ++ G +T S + +++
Sbjct: 210 SGGIDNDIKVWDLRQ-NKLTYTMRGHAD--SVTGLSLSSEGSYLLSNAMDNTVRVWDVRP 266
Query: 455 FFERRTFQRVYEIDI--TDASVVRCLWHPKLNQIMVGTGNGLAKVY 498
F + ++++ ++ + +++RC W P ++I G+ + V+
Sbjct: 267 FAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVYVW 312
Score = 46.6 bits (109), Expect = 7e-05
Identities = 57/235 (24%), Positives = 106/235 (45%), Gaps = 28/235 (11%)
Query: 178 LKHGTKTVSALGLDPSGARLV-TGGYDYDVKFWDFAGMDASFKAFRSLQPCECHQIKSLQ 236
LK T V++ G +LV TG D VK WD A+ + F++ +Q+ ++
Sbjct: 147 LKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIR-KKAAIQTFQNT-----YQVLAVT 200
Query: 237 YSNTGDMILVVSGSSQAKVIDRDGFEVMECIKGDQYIVDMANTKGHTAMLHTGSWHPKIK 296
+++T D I+ + KV D ++ ++G A++ ++ GS+
Sbjct: 201 FNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGH------ADSVTGLSLSSEGSY----- 249
Query: 297 GEFMTCSNDATVRTWEVEN--PKKQ-KSVFKPRTMQGKKVIPTTCTYSRDGNLIAAACQN 353
++ + D TVR W+V PK++ +F+ +K + C++S DG+ IAA +
Sbjct: 250 --LLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNL-LRCSWSPDGSKIAAGSAD 306
Query: 354 GSIQIWDRNLTVHPKFHYKQAHDSGTDTSCVTFSYDGNVLASRGGDDSLKLWDIR 408
+ +WD T + YK +G+ V F D ++ S D L + +I+
Sbjct: 307 RFVYVWD---TTSRRILYKLPGHAGSINE-VAFHPDEPIIISASSDKRLYMGEIQ 357
>gi|26665869 WD repeat domain 51B [Homo sapiens]
Length = 478
Score = 58.5 bits (140), Expect = 2e-08
Identities = 52/227 (22%), Positives = 100/227 (44%), Gaps = 34/227 (14%)
Query: 185 VSALGLDPSGARLVTGGYDYDVKFWDFAGMDASFKAFRSLQPCECHQIKSLQYSNTGDMI 244
+++L L P+G +L T +D + W+F +A+R + + + S+Q+S G+++
Sbjct: 21 ITSLDLSPNGKQLATASWDTFLMLWNFK---PHARAYRYVGHKDV--VTSVQFSPHGNLL 75
Query: 245 LVVSGSSQAK--VIDRDGFEVMECIKGDQYIVDMANTKGHTAMLHTGSWHPKIKGEFM-T 301
S + + D+ G + K HTA + + + G+F+ T
Sbjct: 76 ASASRDRTVRLWIPDKRG--------------KFSEFKAHTAPVRSVDF--SADGQFLAT 119
Query: 302 CSNDATVRTWEVENPKKQKSVFKPRTMQGKKVIPTTCTYSRDGNLIAAACQNGSIQIWDR 361
S D +++ W + + S+++ +S DG LI + ++ +I+IWD
Sbjct: 120 ASEDKSIKVWSMYRQRFLYSLYRHTHWV------RCAKFSPDGRLIVSCSEDKTIKIWDT 173
Query: 362 NLTVHPKFHYKQAHDSGTDTSCVTFSYDGNVLASRGGDDSLKLWDIR 408
K DS + V F+ G +AS G D ++K+WD+R
Sbjct: 174 T----NKQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVKVWDVR 216
Score = 52.8 bits (125), Expect = 1e-06
Identities = 61/294 (20%), Positives = 120/294 (40%), Gaps = 42/294 (14%)
Query: 185 VSALGLDPSGARLVTGGYDYDVKFW--DFAGMDASFKAFRSLQPCECHQIKSLQYSNTGD 242
V+++ P G L + D V+ W D G + FKA + ++S+ +S G
Sbjct: 63 VTSVQFSPHGNLLASASRDRTVRLWIPDKRGKFSEFKAHTA-------PVRSVDFSADGQ 115
Query: 243 MILVVSGSSQAKVIDRDGFEVMECIKGDQYIVDMANTKGHTAMLHTGSWHPKIKGEFMTC 302
+ S KV + +++ + HT + + P + ++C
Sbjct: 116 FLATASEDKSIKVWS---------MYRQRFLYSLYR---HTHWVRCAKFSPDGR-LIVSC 162
Query: 303 SNDATVRTWEVENPKKQKSVFKPRTMQGKKVIPTTCTYSRDGNLIAAACQNGSIQIWDRN 362
S D T++ W+ N K+ + F V ++ G IA+A + ++++WD
Sbjct: 163 SEDKTIKIWDTTN-KQCVNNFSDSVGFANFV-----DFNPSGTCIASAGSDQTVKVWD-- 214
Query: 363 LTVHPKFHYKQAHDSGTDTSCVTFSYDGNVLASRGGDDSLKLWDIRQFNKPLFSASGLPT 422
+ V+ + Q H G + C++F GN L + D +LK+ D+ + + +++ G
Sbjct: 215 VRVNKLLQHYQVHSGGVN--CISFHPSGNYLITASSDGTLKILDLLE-GRLIYTLQG--H 269
Query: 423 MFPMTDCCFSPDDKLIVTGTSIQRGCGSGKLVFFERRTFQRVYEIDITDASVVR 476
P+ FS +L +G G+ V R F ++ +T ++ R
Sbjct: 270 TGPVFTVSFSKGGELFASG-------GADTQVLLWRTNFDELHCKGLTKRNLKR 316
>gi|32483361 apoptotic peptidase activating factor 1 isoform d [Homo
sapiens]
Length = 1205
Score = 56.6 bits (135), Expect = 7e-08
Identities = 65/278 (23%), Positives = 114/278 (41%), Gaps = 45/278 (16%)
Query: 231 QIKSLQYSNTGDMILVVSGSSQAKVIDRDGFEVMECIKGDQYIVDMANTK-GHTAMLHTG 289
Q+ ++N+ +L+ +GSS + D EC NT GHT ++
Sbjct: 701 QVNCCHFTNSSHHLLLATGSSDCFLKLWD-LNQKEC----------RNTMFGHTNSVNHC 749
Query: 290 SWHPKIKGEFMTCSNDATVRTWEVENPKKQKSVFKPR-------TMQGKKVIPTTCTYSR 342
+ P K +CS D T++ W+ + ++KS+ + + +VI C++S
Sbjct: 750 RFSPDDK-LLASCSADGTLKLWDATSANERKSINVKQFFLNLEDPQEDMEVIVKCCSWSA 808
Query: 343 DGNLIAAACQNGSIQIWD---RNLTVHPKFHYKQAHDSGTDTSCVTFSYDGNVLASRGGD 399
DG I A +N I +W+ R+ + H H V FS DG+ + D
Sbjct: 809 DGARIMVAAKN-KIFLWNTDSRSKVADCRGHLSWVHG-------VMFSPDGSSFLTSSDD 860
Query: 400 DSLKLWDIRQFNKPLFSASGLPTMFPMTDCCFSPDDKLIVTGTSIQRGCGSGKLVFFERR 459
+++LW+ ++ K + + D F ++ +++ I+R L R
Sbjct: 861 QTIRLWETKKVCK-----NSAVMLKQEVDVVFQENEVMVLAVDHIRR------LQLINGR 909
Query: 460 TFQRVYEIDITDASVVRCLWHPKLNQIMVGTGNGLAKV 497
T Q Y +T+A V C P L I G NG ++
Sbjct: 910 TGQIDY---LTEAQVSCCCLSPHLQYIAFGDENGAIEI 944
Score = 46.6 bits (109), Expect = 7e-05
Identities = 34/146 (23%), Positives = 63/146 (43%), Gaps = 15/146 (10%)
Query: 300 MTCSNDATVRTWEVENPKKQKSVFKPRTMQGKKVIPTTCTYSRDGNLIAAACQNGSIQIW 359
++ S D TV+ W + K+K QG + +C S D ++ + + +IW
Sbjct: 1016 LSWSFDGTVKVWNIITGNKEKDFV---CHQGTVL---SCDISHDATKFSSTSADKTAKIW 1069
Query: 360 DRNLTVHPKFHYKQAHDSGTDTSCVTFSYDGNVLASRGGDDSLKLWDIRQFN-----KPL 414
+L + H + H+ C FS D +LA+ + +++W++ PL
Sbjct: 1070 SFDLLL--PLHELRGHNGCV--RCSAFSVDSTLLATGDDNGEIRIWNVSNGELLHLCAPL 1125
Query: 415 FSASGLPTMFPMTDCCFSPDDKLIVT 440
+TD CFSPD K++++
Sbjct: 1126 SEEGAATHGGWVTDLCFSPDGKMLIS 1151
Score = 44.3 bits (103), Expect = 4e-04
Identities = 38/144 (26%), Positives = 58/144 (40%), Gaps = 19/144 (13%)
Query: 301 TCSNDATVRTWEVENPKKQKSVFKPRTMQGKKVIPTTCTYSRDGNLIAAACQNGSIQIWD 360
+C D T++ ++ E +K + + + C +S D IA + ++IW
Sbjct: 632 SCGADKTLQVFKAETGEKLLEI------KAHEDEVLCCAFSTDDRFIATCSVDKKVKIW- 684
Query: 361 RNLTVHPKFHYKQAHDSGTDTSCVTFSYDGNVLASRGGDDSLKLWDIRQFNKPLFSASGL 420
N H H + T S +LA+ D LKLWD+ Q
Sbjct: 685 -NSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQ-------KECR 736
Query: 421 PTMFPMTD----CCFSPDDKLIVT 440
TMF T+ C FSPDDKL+ +
Sbjct: 737 NTMFGHTNSVNHCRFSPDDKLLAS 760
Score = 34.3 bits (77), Expect = 0.37
Identities = 61/309 (19%), Positives = 110/309 (35%), Gaps = 59/309 (19%)
Query: 158 EEEEEEENPVHKIPDSHEITLKHGTKT--VSALGLDPSGARLVTGGYDYDVKFWDFAGMD 215
+E E+ N H SH + L G+ + L+ R G+ V F+ D
Sbjct: 696 DEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDD 755
Query: 216 ---ASFKAFRSLQPCECHQIKSLQYSNTGDMILVVSGSSQAKVI-------DRDGFEVME 265
AS A +L+ + + N L + + + DG +M
Sbjct: 756 KLLASCSADGTLKLWDATSANERKSINVKQFFLNLEDPQEDMEVIVKCCSWSADGARIMV 815
Query: 266 CIKGDQYIVD------MANTKGHTAMLHTGSWHPKIKGEFMTCSNDATVRTWEVENPKKQ 319
K ++ + +A+ +GH + +H + P F+T S+D T+R WE + K
Sbjct: 816 AAKNKIFLWNTDSRSKVADCRGHLSWVHGVMFSPD-GSSFLTSSDDQTIRLWETKKVCKN 874
Query: 320 KSVFKPR----TMQGKKVI---------------------------PTTCTYSRDGNLIA 348
+V + Q +V+ + C S IA
Sbjct: 875 SAVMLKQEVDVVFQENEVMVLAVDHIRRLQLINGRTGQIDYLTEAQVSCCCLSPHLQYIA 934
Query: 349 AACQNGSIQIWD--RNLTVHPKFHYKQAHDSGTDTSCVTFSYDGNVLASRGGDDSLKLWD 406
+NG+I+I + N +F +K+ + F+ D L S D +++W+
Sbjct: 935 FGDENGAIEILELVNNRIFQSRFQHKKT------VWHIQFTADEKTLISSSDDAEIQVWN 988
Query: 407 IRQFNKPLF 415
Q +K +F
Sbjct: 989 -WQLDKCIF 996
Score = 30.0 bits (66), Expect = 7.0
Identities = 28/112 (25%), Positives = 41/112 (36%), Gaps = 8/112 (7%)
Query: 301 TCSNDATVRTWEVENPKKQKSVFKPRTMQGKKVIPTTCTYSRDGNLIAAACQNGSIQIWD 360
TCS D V+ W + ++V T S L+A + +++WD
Sbjct: 674 TCSVDKKVKIWN----SMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWD 729
Query: 361 RNLTVHPKFHYKQAHDSGTDTSCVTFSYDGNVLASRGGDDSLKLWDIRQFNK 412
N K + FS D +LAS D +LKLWD N+
Sbjct: 730 LN----QKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANE 777
>gi|4502123 apoptotic peptidase activating factor 1 isoform b [Homo
sapiens]
Length = 1194
Score = 56.6 bits (135), Expect = 7e-08
Identities = 65/278 (23%), Positives = 114/278 (41%), Gaps = 45/278 (16%)
Query: 231 QIKSLQYSNTGDMILVVSGSSQAKVIDRDGFEVMECIKGDQYIVDMANTK-GHTAMLHTG 289
Q+ ++N+ +L+ +GSS + D EC NT GHT ++
Sbjct: 690 QVNCCHFTNSSHHLLLATGSSDCFLKLWD-LNQKEC----------RNTMFGHTNSVNHC 738
Query: 290 SWHPKIKGEFMTCSNDATVRTWEVENPKKQKSVFKPR-------TMQGKKVIPTTCTYSR 342
+ P K +CS D T++ W+ + ++KS+ + + +VI C++S
Sbjct: 739 RFSPDDK-LLASCSADGTLKLWDATSANERKSINVKQFFLNLEDPQEDMEVIVKCCSWSA 797
Query: 343 DGNLIAAACQNGSIQIWD---RNLTVHPKFHYKQAHDSGTDTSCVTFSYDGNVLASRGGD 399
DG I A +N I +W+ R+ + H H V FS DG+ + D
Sbjct: 798 DGARIMVAAKN-KIFLWNTDSRSKVADCRGHLSWVHG-------VMFSPDGSSFLTSSDD 849
Query: 400 DSLKLWDIRQFNKPLFSASGLPTMFPMTDCCFSPDDKLIVTGTSIQRGCGSGKLVFFERR 459
+++LW+ ++ K + + D F ++ +++ I+R L R
Sbjct: 850 QTIRLWETKKVCK-----NSAVMLKQEVDVVFQENEVMVLAVDHIRR------LQLINGR 898
Query: 460 TFQRVYEIDITDASVVRCLWHPKLNQIMVGTGNGLAKV 497
T Q Y +T+A V C P L I G NG ++
Sbjct: 899 TGQIDY---LTEAQVSCCCLSPHLQYIAFGDENGAIEI 933
Score = 46.6 bits (109), Expect = 7e-05
Identities = 34/146 (23%), Positives = 63/146 (43%), Gaps = 15/146 (10%)
Query: 300 MTCSNDATVRTWEVENPKKQKSVFKPRTMQGKKVIPTTCTYSRDGNLIAAACQNGSIQIW 359
++ S D TV+ W + K+K QG + +C S D ++ + + +IW
Sbjct: 1005 LSWSFDGTVKVWNIITGNKEKDFV---CHQGTVL---SCDISHDATKFSSTSADKTAKIW 1058
Query: 360 DRNLTVHPKFHYKQAHDSGTDTSCVTFSYDGNVLASRGGDDSLKLWDIRQFN-----KPL 414
+L + H + H+ C FS D +LA+ + +++W++ PL
Sbjct: 1059 SFDLLL--PLHELRGHNGCV--RCSAFSVDSTLLATGDDNGEIRIWNVSNGELLHLCAPL 1114
Query: 415 FSASGLPTMFPMTDCCFSPDDKLIVT 440
+TD CFSPD K++++
Sbjct: 1115 SEEGAATHGGWVTDLCFSPDGKMLIS 1140
Score = 44.3 bits (103), Expect = 4e-04
Identities = 38/144 (26%), Positives = 58/144 (40%), Gaps = 19/144 (13%)
Query: 301 TCSNDATVRTWEVENPKKQKSVFKPRTMQGKKVIPTTCTYSRDGNLIAAACQNGSIQIWD 360
+C D T++ ++ E +K + + + C +S D IA + ++IW
Sbjct: 621 SCGADKTLQVFKAETGEKLLEI------KAHEDEVLCCAFSTDDRFIATCSVDKKVKIW- 673
Query: 361 RNLTVHPKFHYKQAHDSGTDTSCVTFSYDGNVLASRGGDDSLKLWDIRQFNKPLFSASGL 420
N H H + T S +LA+ D LKLWD+ Q
Sbjct: 674 -NSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQ-------KECR 725
Query: 421 PTMFPMTD----CCFSPDDKLIVT 440
TMF T+ C FSPDDKL+ +
Sbjct: 726 NTMFGHTNSVNHCRFSPDDKLLAS 749
Score = 34.3 bits (77), Expect = 0.37
Identities = 61/309 (19%), Positives = 110/309 (35%), Gaps = 59/309 (19%)
Query: 158 EEEEEEENPVHKIPDSHEITLKHGTKT--VSALGLDPSGARLVTGGYDYDVKFWDFAGMD 215
+E E+ N H SH + L G+ + L+ R G+ V F+ D
Sbjct: 685 DEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDD 744
Query: 216 ---ASFKAFRSLQPCECHQIKSLQYSNTGDMILVVSGSSQAKVI-------DRDGFEVME 265
AS A +L+ + + N L + + + DG +M
Sbjct: 745 KLLASCSADGTLKLWDATSANERKSINVKQFFLNLEDPQEDMEVIVKCCSWSADGARIMV 804
Query: 266 CIKGDQYIVD------MANTKGHTAMLHTGSWHPKIKGEFMTCSNDATVRTWEVENPKKQ 319
K ++ + +A+ +GH + +H + P F+T S+D T+R WE + K
Sbjct: 805 AAKNKIFLWNTDSRSKVADCRGHLSWVHGVMFSPD-GSSFLTSSDDQTIRLWETKKVCKN 863
Query: 320 KSVFKPR----TMQGKKVI---------------------------PTTCTYSRDGNLIA 348
+V + Q +V+ + C S IA
Sbjct: 864 SAVMLKQEVDVVFQENEVMVLAVDHIRRLQLINGRTGQIDYLTEAQVSCCCLSPHLQYIA 923
Query: 349 AACQNGSIQIWD--RNLTVHPKFHYKQAHDSGTDTSCVTFSYDGNVLASRGGDDSLKLWD 406
+NG+I+I + N +F +K+ + F+ D L S D +++W+
Sbjct: 924 FGDENGAIEILELVNNRIFQSRFQHKKT------VWHIQFTADEKTLISSSDDAEIQVWN 977
Query: 407 IRQFNKPLF 415
Q +K +F
Sbjct: 978 -WQLDKCIF 985
Score = 30.0 bits (66), Expect = 7.0
Identities = 28/112 (25%), Positives = 41/112 (36%), Gaps = 8/112 (7%)
Query: 301 TCSNDATVRTWEVENPKKQKSVFKPRTMQGKKVIPTTCTYSRDGNLIAAACQNGSIQIWD 360
TCS D V+ W + ++V T S L+A + +++WD
Sbjct: 663 TCSVDKKVKIWN----SMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWD 718
Query: 361 RNLTVHPKFHYKQAHDSGTDTSCVTFSYDGNVLASRGGDDSLKLWDIRQFNK 412
N K + FS D +LAS D +LKLWD N+
Sbjct: 719 LN----QKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANE 766
>gi|21536371 telomerase-associated protein 1 [Homo sapiens]
Length = 2627
Score = 55.1 bits (131), Expect = 2e-07
Identities = 65/261 (24%), Positives = 107/261 (40%), Gaps = 48/261 (18%)
Query: 193 SGARLVTGGYDYDVKFWDFA-GMDASFKAFRSLQPCECHQIKSLQYSNTGDMILVVSGSS 251
+G +L+T G D V+ W + G SL P S+ S GD + V +
Sbjct: 1895 AGCQLLTAGEDGKVQVWSGSLGRPRGHLGSLSLSPA-----LSVALSPDGDRVAVGYRA- 1948
Query: 252 QAKVIDRDGFEVMECIKGDQYIVDMANTKGHTAMLHTGSW-HPKIKGEFMTCSNDATVRT 310
DG + + G Q A +A+ +W PK+ ++ + D +++
Sbjct: 1949 -------DGIRIYKISSGSQGAQGQALDVAVSAL----AWLSPKV---LVSGAEDGSLQG 1994
Query: 311 WEVENPKKQKSVFKPRTMQGKKVIPTTCTYSRDGNLIAAACQNGSIQIWDRNLTVHPKFH 370
W ++ Q R + + T+ L+A+A ++ ++Q+W R L P H
Sbjct: 1995 WALKECSLQSLWLLSRFQKPVLGLATS------QELLASASEDFTVQLWPRQLLTRP--H 2046
Query: 371 YKQAHDSGTD-------TSCVTFSYDGNVLASRGGDDSLKLWDIRQFNKPLFSASGLPTM 423
+ GT+ SC +FS DG LA+ G D SL WD+R P+ S
Sbjct: 2047 KAEDFPCGTELRGHEGPVSCCSFSTDGGSLATGGRDRSLLCWDVRTPKTPVLIHS----- 2101
Query: 424 FP------MTDCCFSPDDKLI 438
FP +T C ++ D+ LI
Sbjct: 2102 FPACHRDWVTGCAWTKDNLLI 2122
Score = 41.2 bits (95), Expect = 0.003
Identities = 33/141 (23%), Positives = 61/141 (43%), Gaps = 19/141 (13%)
Query: 309 RTWEVENPKKQKSVFKPRTMQGKKVI---------PTTCTYSRDGNLIAAACQNGSIQIW 359
R W +++ + + KPRTM+ ++ PT +S +G A NG++ +
Sbjct: 1646 RRWHLQHTLRWLN--KPRTMKNQQSSSLSLAVSSSPTAVAFSTNGQRAAVGTANGTVYLL 1703
Query: 360 DRNLTVHPKFHYKQAHDSGTDTSCVTFSYDGNVLASRGGDDSLKLWDIRQFNKPLFSASG 419
D + +++ SG D + L D L+LWD++ + L + +
Sbjct: 1704 DLRT-----WQEEKSVVSGCDGISACLFLSDDTLFLTAFDGLLELWDLQHGCRVLQTKAH 1758
Query: 420 LPTMFPMTDCCFSPDDKLIVT 440
+ +T CC SPD +L+ T
Sbjct: 1759 ---QYQITGCCLSPDCRLLAT 1776
Score = 35.8 bits (81), Expect = 0.13
Identities = 20/72 (27%), Positives = 34/72 (47%), Gaps = 5/72 (6%)
Query: 336 TTCTYSRDGNLIAAACQNGSIQIWDRNLTVHPKFHYKQAHDSGTDTSCVTFSYDGNVLAS 395
T C S D L+A C G +++WD TV + ++ H +CV F +G V+A+
Sbjct: 1763 TGCCLSPDCRLLATVCLGGCLKLWD---TVRGQLAFQ--HTYPKSLNCVAFHPEGQVIAT 1817
Query: 396 RGGDDSLKLWDI 407
S+ + +
Sbjct: 1818 GSWAGSISFFQV 1829
Score = 33.1 bits (74), Expect = 0.83
Identities = 25/110 (22%), Positives = 45/110 (40%), Gaps = 9/110 (8%)
Query: 297 GEFMTCSNDATVRTWEVENPKKQKSVFKPRTMQGKKVIPTTCTYSRDGNLIAAACQNGSI 356
G T D ++ W+V PK + V T C +++D NL+ + +GS+
Sbjct: 2074 GSLATGGRDRSLLCWDVRTPKTPVLIHSFPACHRDWV--TGCAWTKD-NLLISCSSDGSV 2130
Query: 357 QIWDRNLTVHPKFHYKQAHDSGTDTSCVTFSYDGNVLASRGGDDSLKLWD 406
+WD P+ + G ++ + + S D +LK+WD
Sbjct: 2131 GLWD------PESGQRLGQFLGHQSAVSAVAAVEEHVVSVSRDGTLKVWD 2174
>gi|207029439 retinoblastoma binding protein 4 isoform c [Homo
sapiens]
Length = 390
Score = 54.7 bits (130), Expect = 3e-07
Identities = 34/141 (24%), Positives = 65/141 (46%), Gaps = 6/141 (4%)
Query: 280 KGHTAMLHTGSWHPKIKGEFMTCSNDATVRTWEVENPKKQKSVFKPRTM--QGKKVIPTT 337
+GH + SW+P + G ++ S+D T+ W++ K+ V +T+ V+
Sbjct: 139 RGHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDV 198
Query: 338 CTYSRDGNLIAAACQNGSIQIWD-RNLTVHPKFHYKQAHDSGTDTSCVTFS-YDGNVLAS 395
+ +L + + + IWD R+ H AH + + +C++F+ Y +LA+
Sbjct: 199 SWHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTA--EVNCLSFNPYSEFILAT 256
Query: 396 RGGDDSLKLWDIRQFNKPLFS 416
D ++ LWD+R L S
Sbjct: 257 GSADKTVALWDLRNLKLKLHS 277
Score = 40.0 bits (92), Expect = 0.007
Identities = 38/178 (21%), Positives = 77/178 (43%), Gaps = 23/178 (12%)
Query: 281 GHTAMLHTGSWHPKIKGEFMTCSNDATVRTWEVENPKKQKSVFKPRTMQGKKVIPTTCTY 340
GHTA++ SWH + F + ++D + W+ + + KP C
Sbjct: 190 GHTAVVEDVSWHLLHESLFGSVADDQKLMIWDT----RSNNTSKPSHSVDAHTAEVNCLS 245
Query: 341 SRDGN--LIAAACQNGSIQIWD-RNLTVHPKFHYKQAHDSGTDTSCVTFS-YDGNVLASR 396
+ ++A + ++ +WD RNL + K H ++H + V +S ++ +LAS
Sbjct: 246 FNPYSEFILATGSADKTVALWDLRNLKL--KLHSFESHKD--EIFQVQWSPHNETILASS 301
Query: 397 GGDDSLKLWDIRQFNK---PLFSASGLPTMF--------PMTDCCFSPDDKLIVTGTS 443
G D L +WD+ + + P + G P + ++D ++P++ ++ S
Sbjct: 302 GTDRRLNVWDLSKIGEEQSPEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVS 359
Score = 37.0 bits (84), Expect = 0.057
Identities = 38/156 (24%), Positives = 63/156 (40%), Gaps = 24/156 (15%)
Query: 166 PVHKIPDSHEITLKHGTKTVSALGLDP-SGARLVTGGYDYDVKFWDFAGMDASFKAFRSL 224
P H + D+H T V+ L +P S L TG D V WD + +F S
Sbjct: 230 PSHSV-DAH-------TAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESH 281
Query: 225 QPCECHQIKSLQYSNTGDMILVVSGSSQ-------AKVIDRDGFEVMECIKGDQYIVDMA 277
+ +I +Q+S + IL SG+ + +K+ + E E + +
Sbjct: 282 KD----EIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPELLFIH-- 335
Query: 278 NTKGHTAMLHTGSWHPKIKGEFMTCSNDATVRTWEV 313
GHTA + SW+P + S D ++ W++
Sbjct: 336 --GGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQM 369
>gi|207029415 retinoblastoma binding protein 4 isoform b [Homo
sapiens]
Length = 424
Score = 54.7 bits (130), Expect = 3e-07
Identities = 34/141 (24%), Positives = 65/141 (46%), Gaps = 6/141 (4%)
Query: 280 KGHTAMLHTGSWHPKIKGEFMTCSNDATVRTWEVENPKKQKSVFKPRTM--QGKKVIPTT 337
+GH + SW+P + G ++ S+D T+ W++ K+ V +T+ V+
Sbjct: 173 RGHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDV 232
Query: 338 CTYSRDGNLIAAACQNGSIQIWD-RNLTVHPKFHYKQAHDSGTDTSCVTFS-YDGNVLAS 395
+ +L + + + IWD R+ H AH + + +C++F+ Y +LA+
Sbjct: 233 SWHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTA--EVNCLSFNPYSEFILAT 290
Query: 396 RGGDDSLKLWDIRQFNKPLFS 416
D ++ LWD+R L S
Sbjct: 291 GSADKTVALWDLRNLKLKLHS 311
Score = 40.0 bits (92), Expect = 0.007
Identities = 38/178 (21%), Positives = 77/178 (43%), Gaps = 23/178 (12%)
Query: 281 GHTAMLHTGSWHPKIKGEFMTCSNDATVRTWEVENPKKQKSVFKPRTMQGKKVIPTTCTY 340
GHTA++ SWH + F + ++D + W+ + + KP C
Sbjct: 224 GHTAVVEDVSWHLLHESLFGSVADDQKLMIWDT----RSNNTSKPSHSVDAHTAEVNCLS 279
Query: 341 SRDGN--LIAAACQNGSIQIWD-RNLTVHPKFHYKQAHDSGTDTSCVTFS-YDGNVLASR 396
+ ++A + ++ +WD RNL + K H ++H + V +S ++ +LAS
Sbjct: 280 FNPYSEFILATGSADKTVALWDLRNLKL--KLHSFESHKD--EIFQVQWSPHNETILASS 335
Query: 397 GGDDSLKLWDIRQFNK---PLFSASGLPTMF--------PMTDCCFSPDDKLIVTGTS 443
G D L +WD+ + + P + G P + ++D ++P++ ++ S
Sbjct: 336 GTDRRLNVWDLSKIGEEQSPEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVS 393
Score = 37.0 bits (84), Expect = 0.057
Identities = 38/156 (24%), Positives = 63/156 (40%), Gaps = 24/156 (15%)
Query: 166 PVHKIPDSHEITLKHGTKTVSALGLDP-SGARLVTGGYDYDVKFWDFAGMDASFKAFRSL 224
P H + D+H T V+ L +P S L TG D V WD + +F S
Sbjct: 264 PSHSV-DAH-------TAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESH 315
Query: 225 QPCECHQIKSLQYSNTGDMILVVSGSSQ-------AKVIDRDGFEVMECIKGDQYIVDMA 277
+ +I +Q+S + IL SG+ + +K+ + E E + +
Sbjct: 316 KD----EIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPELLFIH-- 369
Query: 278 NTKGHTAMLHTGSWHPKIKGEFMTCSNDATVRTWEV 313
GHTA + SW+P + S D ++ W++
Sbjct: 370 --GGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQM 403
>gi|5032027 retinoblastoma binding protein 4 isoform a [Homo
sapiens]
Length = 425
Score = 54.7 bits (130), Expect = 3e-07
Identities = 34/141 (24%), Positives = 65/141 (46%), Gaps = 6/141 (4%)
Query: 280 KGHTAMLHTGSWHPKIKGEFMTCSNDATVRTWEVENPKKQKSVFKPRTM--QGKKVIPTT 337
+GH + SW+P + G ++ S+D T+ W++ K+ V +T+ V+
Sbjct: 174 RGHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDV 233
Query: 338 CTYSRDGNLIAAACQNGSIQIWD-RNLTVHPKFHYKQAHDSGTDTSCVTFS-YDGNVLAS 395
+ +L + + + IWD R+ H AH + + +C++F+ Y +LA+
Sbjct: 234 SWHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTA--EVNCLSFNPYSEFILAT 291
Query: 396 RGGDDSLKLWDIRQFNKPLFS 416
D ++ LWD+R L S
Sbjct: 292 GSADKTVALWDLRNLKLKLHS 312
Score = 40.0 bits (92), Expect = 0.007
Identities = 38/178 (21%), Positives = 77/178 (43%), Gaps = 23/178 (12%)
Query: 281 GHTAMLHTGSWHPKIKGEFMTCSNDATVRTWEVENPKKQKSVFKPRTMQGKKVIPTTCTY 340
GHTA++ SWH + F + ++D + W+ + + KP C
Sbjct: 225 GHTAVVEDVSWHLLHESLFGSVADDQKLMIWDT----RSNNTSKPSHSVDAHTAEVNCLS 280
Query: 341 SRDGN--LIAAACQNGSIQIWD-RNLTVHPKFHYKQAHDSGTDTSCVTFS-YDGNVLASR 396
+ ++A + ++ +WD RNL + K H ++H + V +S ++ +LAS
Sbjct: 281 FNPYSEFILATGSADKTVALWDLRNLKL--KLHSFESHKD--EIFQVQWSPHNETILASS 336
Query: 397 GGDDSLKLWDIRQFNK---PLFSASGLPTMF--------PMTDCCFSPDDKLIVTGTS 443
G D L +WD+ + + P + G P + ++D ++P++ ++ S
Sbjct: 337 GTDRRLNVWDLSKIGEEQSPEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVS 394
Score = 37.0 bits (84), Expect = 0.057
Identities = 38/156 (24%), Positives = 63/156 (40%), Gaps = 24/156 (15%)
Query: 166 PVHKIPDSHEITLKHGTKTVSALGLDP-SGARLVTGGYDYDVKFWDFAGMDASFKAFRSL 224
P H + D+H T V+ L +P S L TG D V WD + +F S
Sbjct: 265 PSHSV-DAH-------TAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESH 316
Query: 225 QPCECHQIKSLQYSNTGDMILVVSGSSQ-------AKVIDRDGFEVMECIKGDQYIVDMA 277
+ +I +Q+S + IL SG+ + +K+ + E E + +
Sbjct: 317 KD----EIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPELLFIH-- 370
Query: 278 NTKGHTAMLHTGSWHPKIKGEFMTCSNDATVRTWEV 313
GHTA + SW+P + S D ++ W++
Sbjct: 371 --GGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQM 404
>gi|124256480 APG16 autophagy 16-like isoform 1 [Homo sapiens]
Length = 607
Score = 54.7 bits (130), Expect = 3e-07
Identities = 88/429 (20%), Positives = 155/429 (36%), Gaps = 49/429 (11%)
Query: 22 AVTMGFTGFGKKARTFDLEAMFEQTRRTAVERSRKTLEAREKEEEMNREKELRRQNEDIE 81
A+ + FT K R E E R E++++ + E+ +R ++ R Q E E
Sbjct: 168 ALQITFTALEGKLRKTTEENQ-ELVTRWMAEKAQEANRLNAENEKDSRRRQARLQKELAE 226
Query: 82 PTSSRSNVVRDCSKSSSRDTSSSESEQSSD------SSDDELIGPPLPPKMVGKPVNFME 135
V +D D +S +E++S ++ L P ++ N
Sbjct: 227 AAKEPLPVEQDDDIEVIVDETSDHTEETSPVRAISRAATKRLSQPA--GGLLDSITNIFG 284
Query: 136 EDILGPLPPPLNEEEEEAEEEEEEEEEEENPVHKIPDSHEITLKHGTKTVSALGLDPSGA 195
+ P P + + +E ++P + V+A+ P
Sbjct: 285 RRSVSSFPVPQDNVDTHPGSGKEV---------RVPATALCVFDAHDGEVNAVQFSPGSR 335
Query: 196 RLVTGGYDYDVKFWDFAGMDASFKAFRSLQPCECHQIKSLQYSNTGDMILVVSGSSQAKV 255
L TGG D VK W+ G FK S I S+++ + G +L S +++
Sbjct: 336 LLATGGMDRRVKLWEVFGEKCEFKGSLSGSNA---GITSIEFDSAGSYLLAASNDFASRI 392
Query: 256 IDRDGFEVMECIKGDQYIVDMANTKGHTAMLHTGSWHPKIKGEFMTCSNDATVRTWEVEN 315
D + + + G V A A + +G S+D T++ W++ +
Sbjct: 393 WTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSG-------------SHDRTLKLWDLRS 439
Query: 316 PKKQKSVFKPRTMQGKKVIPTTCTYSRDGNLIAAACQNGSIQIWDRNLTVHPKFHYKQAH 375
K+VF G CT + + + I+ WD + + ++
Sbjct: 440 KVCIKTVF-----AGSSCNDIVCT----EQCVMSGHFDKKIRFWD----IRSESIVREME 486
Query: 376 DSGTDTSCVTFSYDGNVLASRGGDDSLKLWDIR-QFNKPLFSASGLPTMFPMTDCCFSPD 434
G T+ + + + L S DD LK+ D+R K FSA G T FSPD
Sbjct: 487 LLGKITA-LDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPD 545
Query: 435 DKLIVTGTS 443
+ G++
Sbjct: 546 GSYVAAGSA 554
Score = 35.0 bits (79), Expect = 0.22
Identities = 42/180 (23%), Positives = 72/180 (40%), Gaps = 25/180 (13%)
Query: 180 HGTKTVSALGLDPSGARLVTGGYDYDVKFWDFAGMDASFKAFRSLQPCECHQIKSLQYSN 239
H K +SA L AR+V+G +D +K WD F C+ I +
Sbjct: 407 HSGKVLSAKFL-LDNARIVSGSHDRTLKLWDLRSKVCIKTVFAG---SSCNDIVCTEQC- 461
Query: 240 TGDMILVVSGSSQAKVIDRDGFEVMECIKGDQYIVDMANTKGHTAMLHTGSWHPKIKGEF 299
V+SG K+ D I+ + + +M TA+ +P+ + E
Sbjct: 462 ------VMSGHFDKKIRFWD-------IRSESIVREMELLGKITAL----DLNPE-RTEL 503
Query: 300 MTCSNDATVRTWEVENPKKQKSVFKPRTMQGKKVIPTTCTYSRDGNLIAAACQNGSIQIW 359
++CS D ++ ++ +++ P G T +S DG+ +AA GS+ IW
Sbjct: 504 LSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDW--TRVVFSPDGSYVAAGSAEGSLYIW 561
>gi|124256478 APG16 autophagy 16-like isoform 2 [Homo sapiens]
Length = 588
Score = 54.7 bits (130), Expect = 3e-07
Identities = 86/423 (20%), Positives = 153/423 (36%), Gaps = 56/423 (13%)
Query: 22 AVTMGFTGFGKKARTFDLEAMFEQTRRTAVERSRKTLEAREKEEEMNREKELRRQNEDIE 81
A+ + FT K R E E R E++++ + E+ +R ++ R Q E E
Sbjct: 168 ALQITFTALEGKLRKTTEENQ-ELVTRWMAEKAQEANRLNAENEKDSRRRQARLQKELAE 226
Query: 82 PTSSRSNVVRDCSKSSSRDTSSSESEQSSDSSDDELIGPPLPPKMVGKPVNFMEEDILGP 141
V +D D +S +E++S P + + +
Sbjct: 227 AAKEPLPVEQDDDIEVIVDETSDHTEETS------------PVRAISRAATRRSVSSF-- 272
Query: 142 LPPPLNEEEEEAEEEEEEEEEEENPVHKIPDSHEITLKHGTKTVSALGLDPSGARLVTGG 201
P+ ++ + +E + D+H+ V+A+ P L TGG
Sbjct: 273 ---PVPQDNVDTHPGSGKEVRVPATALCVFDAHD-------GEVNAVQFSPGSRLLATGG 322
Query: 202 YDYDVKFWDFAGMDASFKAFRSLQPCECHQIKSLQYSNTGDMILVVSGSSQAKVIDRDGF 261
D VK W+ G FK S I S+++ + G +L S +++ D +
Sbjct: 323 MDRRVKLWEVFGEKCEFKGSLSGSNA---GITSIEFDSAGSYLLAASNDFASRIWTVDDY 379
Query: 262 EVMECIKGDQYIVDMANTKGHTAMLHTGSWHPKIKGEFMTCSNDATVRTWEVENPKKQKS 321
+ + G V A A + +G S+D T++ W++ + K+
Sbjct: 380 RLRHTLTGHSGKVLSAKFLLDNARIVSG-------------SHDRTLKLWDLRSKVCIKT 426
Query: 322 VFKPRTMQGKKVIPTTCTYSRDGNLIAAACQNGSIQIWDRNLTVHPKFHYKQAHDSGTDT 381
VF G CT + + + I+ WD + + ++ G T
Sbjct: 427 VF-----AGSSCNDIVCT----EQCVMSGHFDKKIRFWD----IRSESIVREMELLGKIT 473
Query: 382 SCVTFSYDGNVLASRGGDDSLKLWDIR-QFNKPLFSASGLPTMFPMTDCCFSPDDKLIVT 440
+ + + + L S DD LK+ D+R K FSA G T FSPD +
Sbjct: 474 A-LDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVAA 532
Query: 441 GTS 443
G++
Sbjct: 533 GSA 535
Score = 35.0 bits (79), Expect = 0.22
Identities = 42/180 (23%), Positives = 72/180 (40%), Gaps = 25/180 (13%)
Query: 180 HGTKTVSALGLDPSGARLVTGGYDYDVKFWDFAGMDASFKAFRSLQPCECHQIKSLQYSN 239
H K +SA L AR+V+G +D +K WD F C+ I +
Sbjct: 388 HSGKVLSAKFL-LDNARIVSGSHDRTLKLWDLRSKVCIKTVFAG---SSCNDIVCTEQC- 442
Query: 240 TGDMILVVSGSSQAKVIDRDGFEVMECIKGDQYIVDMANTKGHTAMLHTGSWHPKIKGEF 299
V+SG K+ D I+ + + +M TA+ +P+ + E
Sbjct: 443 ------VMSGHFDKKIRFWD-------IRSESIVREMELLGKITAL----DLNPE-RTEL 484
Query: 300 MTCSNDATVRTWEVENPKKQKSVFKPRTMQGKKVIPTTCTYSRDGNLIAAACQNGSIQIW 359
++CS D ++ ++ +++ P G T +S DG+ +AA GS+ IW
Sbjct: 485 LSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDW--TRVVFSPDGSYVAAGSAEGSLYIW 542
>gi|4506439 retinoblastoma binding protein 7 [Homo sapiens]
Length = 425
Score = 53.9 bits (128), Expect = 5e-07
Identities = 36/139 (25%), Positives = 64/139 (46%), Gaps = 6/139 (4%)
Query: 280 KGHTAMLHTGSWHPKIKGEFMTCSNDATVRTWEVE-NPKKQKSVFKPRTMQG-KKVIPTT 337
+GH + SW+ + G ++ S+D TV W++ PK+ K V G V+
Sbjct: 173 RGHQKEGYGLSWNSNLSGHLLSASDDHTVCLWDINAGPKEGKIVDAKAIFTGHSAVVEDV 232
Query: 338 CTYSRDGNLIAAACQNGSIQIWD-RNLTVHPKFHYKQAHDSGTDTSCVTFS-YDGNVLAS 395
+ +L + + + IWD R+ T H AH + + +C++F+ Y +LA+
Sbjct: 233 AWHLLHESLFGSVADDQKLMIWDTRSNTTSKPSHLVDAHTA--EVNCLSFNPYSEFILAT 290
Query: 396 RGGDDSLKLWDIRQFNKPL 414
D ++ LWD+R L
Sbjct: 291 GSADKTVALWDLRNLKLKL 309
Score = 37.7 bits (86), Expect = 0.034
Identities = 30/136 (22%), Positives = 62/136 (45%), Gaps = 12/136 (8%)
Query: 281 GHTAMLHTGSWHPKIKGEFMTCSNDATVRTWEVENPKKQKSVFKPRTMQGKKVIPTTCTY 340
GH+A++ +WH + F + ++D + W+ + + KP + C
Sbjct: 224 GHSAVVEDVAWHLLHESLFGSVADDQKLMIWDT----RSNTTSKPSHLVDAHTAEVNCLS 279
Query: 341 SRDGN--LIAAACQNGSIQIWD-RNLTVHPKFHYKQAHDSGTDTSCVTFS-YDGNVLASR 396
+ ++A + ++ +WD RNL + K H ++H + V +S ++ +LAS
Sbjct: 280 FNPYSEFILATGSADKTVALWDLRNLKL--KLHTFESHKD--EIFQVHWSPHNETILASS 335
Query: 397 GGDDSLKLWDIRQFNK 412
G D L +WD+ + +
Sbjct: 336 GTDRRLNVWDLSKIGE 351
Score = 34.7 bits (78), Expect = 0.28
Identities = 33/140 (23%), Positives = 55/140 (39%), Gaps = 16/140 (11%)
Query: 182 TKTVSALGLDP-SGARLVTGGYDYDVKFWDFAGMDASFKAFRSLQPCECHQIKSLQYSNT 240
T V+ L +P S L TG D V WD + F S + +I + +S
Sbjct: 272 TAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHTFESHKD----EIFQVHWSPH 327
Query: 241 GDMILVVSGSSQ-------AKVIDRDGFEVMECIKGDQYIVDMANTKGHTAMLHTGSWHP 293
+ IL SG+ + +K+ + E E + + GHTA + SW+P
Sbjct: 328 NETILASSGTDRRLNVWDLSKIGEEQSAEDAEDGPPELLFIH----GGHTAKISDFSWNP 383
Query: 294 KIKGEFMTCSNDATVRTWEV 313
+ S D ++ W++
Sbjct: 384 NEPWVICSVSEDNIMQIWQM 403
>gi|55743075 angio-associated, migratory cell protein [Homo sapiens]
Length = 434
Score = 53.1 bits (126), Expect = 8e-07
Identities = 80/319 (25%), Positives = 114/319 (35%), Gaps = 53/319 (16%)
Query: 105 ESEQSSDSSDDELIGPPLPPKMVGKPVNFMEEDILGPLPPPLNEEEEEAEEEEEEEEEEE 164
ESE S ++ D PPL +E L P PP ++ +E E+ + EEEEEE
Sbjct: 2 ESESESGAAADT---PPLETLSFHGDEEIIEVVELDPGPPDPDDLAQEMEDVDFEEEEEE 58
Query: 165 ---------NPVHKI------PDSHEITLKHGTKTVSALGLDPSGARL-VTGGYDYDVKF 208
P + PD E+T + +V + LDP L VTGG D
Sbjct: 59 EGNEEGWVLEPQEGVVGSMEGPDDSEVTFALHSASVFCVSLDPKTNTLAVTGGEDDKAFV 118
Query: 209 WDFAGMDASFKAFRSLQPCECHQIKSLQYSNTGDMILVVSG--SSQAKVIDRD-GFEVME 265
W + + F+ C H+ + D LV +G S KV D EV
Sbjct: 119 WRLSDGELLFE-------CAGHKDSVTCAGFSHDSTLVATGDMSGLLKVWQVDTKEEVWS 171
Query: 266 CIKGDQYIVDMANTKGHTAMLHTGSWHPKIKGEFMTCSNDATVRTWEVENPKKQKSVFKP 325
GD L WHP+ + + D W+V N
Sbjct: 172 FEAGD---------------LEWMEWHPRAP-VLLAGTADGNTWMWKVPNG-------DC 208
Query: 326 RTMQGKKVIPTTCTYSRDGNLIAAACQNGSIQIWDRNLTVHPKFHYKQAHDSGTDTSCVT 385
+T QG T DG ++G+I+IWD P K +CV
Sbjct: 209 KTFQGPNCPATCGRVLPDGKRAVVGYEDGTIRIWDLK-QGSPIHVLKGTEGHQGPLTCVA 267
Query: 386 FSYDGNVLASRGGDDSLKL 404
+ DG+++ + D KL
Sbjct: 268 ANQDGSLILTGSVDCQAKL 286
Score = 39.3 bits (90), Expect = 0.012
Identities = 34/121 (28%), Positives = 53/121 (43%), Gaps = 12/121 (9%)
Query: 383 CVTFSYDGNVLASRGG-DDSLKLWDIRQFNKPLFSASGLPTMFPMTDCCFSPDDKLIVTG 441
CV+ N LA GG DD +W + + LF +G +T FS D L+ TG
Sbjct: 96 CVSLDPKTNTLAVTGGEDDKAFVWRLSD-GELLFECAGHKDS--VTCAGFSHDSTLVATG 152
Query: 442 TSIQRGCGSGKLVFFERRTFQRVYEIDITDASVVRCLWHPKLNQIMVGTGNGLAKVYYDP 501
SG L ++ T + V+ + D + WHP+ ++ GT +G ++ P
Sbjct: 153 DM------SGLLKVWQVDTKEEVWSFEAGDLEWME--WHPRAPVLLAGTADGNTWMWKVP 204
Query: 502 N 502
N
Sbjct: 205 N 205
>gi|21071067 TBP-associated factor 5 [Homo sapiens]
Length = 800
Score = 52.0 bits (123), Expect = 2e-06
Identities = 41/130 (31%), Positives = 59/130 (45%), Gaps = 19/130 (14%)
Query: 281 GHTAMLHTGSWHPKIKGEFMTCSNDATVRTWEVENPKKQKSVFKPRTMQGKKVIPTTCTY 340
GH A ++ +HP T S D TVR W+V N R G K + T+
Sbjct: 625 GHLADVNCTRFHPN-SNYVATGSADRTVRLWDVLNGNCV------RIFTGHKGPIHSLTF 677
Query: 341 SRDGNLIAAACQNGSIQIWDRN---LTVHPKFHYKQAHDSGTDTSC-VTFSYDGNVLASR 396
S +G +A +G + +WD + K H TDT C + FS DG +LAS
Sbjct: 678 SPNGRFLATGATDGRVLLWDIGHGLMVGELKGH--------TDTVCSLRFSRDGEILASG 729
Query: 397 GGDDSLKLWD 406
D++++LWD
Sbjct: 730 SMDNTVRLWD 739
Score = 45.1 bits (105), Expect = 2e-04
Identities = 43/227 (18%), Positives = 85/227 (37%), Gaps = 54/227 (23%)
Query: 237 YSNTGDMILVVSGSSQAKVIDRDGFEVMECIKGDQYIVDMANTKGHTAMLHTGSWHPKIK 296
+S T + V +S +ID++ +V+E I ++ ++ GH+ ++ S+ P +
Sbjct: 497 WSVTPKKLRSVKQASDLSLIDKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPD-R 555
Query: 297 GEFMTCSNDATVRTWEVENPKKQKSVFKPRTMQGKKVIPTTCTYSRDGNLIAAACQNGSI 356
++ S D TVR W ++ TC G+ +
Sbjct: 556 NYLLSSSEDGTVRLWSLQT--------------------FTCLVGYKGH---------NY 586
Query: 357 QIWDRNLTVHPKFHYKQAHDSG-------------------TDTSCVTFSYDGNVLASRG 397
+WD + + + HD D +C F + N +A+
Sbjct: 587 PVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGS 646
Query: 398 GDDSLKLWDIRQFN-KPLFSASGLPTMFPMTDCCFSPDDKLIVTGTS 443
D +++LWD+ N +F+ P+ FSP+ + + TG +
Sbjct: 647 ADRTVRLWDVLNGNCVRIFTGH----KGPIHSLTFSPNGRFLATGAT 689
Score = 33.1 bits (74), Expect = 0.83
Identities = 45/194 (23%), Positives = 76/194 (39%), Gaps = 30/194 (15%)
Query: 305 DATVRTWEVENPKKQKSVFKPRTMQGKKVIPTTCTYSRDGNLIAAACQNGSIQIWDRNLT 364
D+TVR W V PKK +SV + + D +LI + +I D
Sbjct: 491 DSTVRVWSV-TPKKLRSVKQ----------------ASDLSLIDKESDDVLERIMDEKTA 533
Query: 365 VHPKFHYKQAHDSGTDTSCVTFSYDGNVLASRGGDDSLKLWDIRQFNKPLFSASGLPTMF 424
K Y + +FS D N L S D +++LW ++ F L G +
Sbjct: 534 SELKILYGHSGP----VYGASFSPDRNYLLSSSEDGTVRLWSLQTFT-CLVGYKG--HNY 586
Query: 425 PMTDCCFSPDDKLIVTGTSIQRGCGSGKLVFFERRTFQRVYEIDITDASVVRCLWHPKLN 484
P+ D FSP V+G + +L + R++ + D + R +HP N
Sbjct: 587 PVWDTQFSPYGYYFVSGGHDR----VARLWATDHYQPLRIFAGHLADVNCTR--FHPNSN 640
Query: 485 QIMVGTGNGLAKVY 498
+ G+ + +++
Sbjct: 641 YVATGSADRTVRLW 654
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 51.2 bits (121), Expect = 3e-06
Identities = 41/150 (27%), Positives = 63/150 (42%), Gaps = 17/150 (11%)
Query: 59 EAREKEEEMNREKELRRQNEDIEPTSSRSNVVRDCSKSSSRDTSSSESEQSSDSSDDE-- 116
E+ +E+E E+E + E+ E + RD S++ DT+ SE+ + + DE
Sbjct: 1039 ESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEGDSDEEE 1098
Query: 117 ---LIGPPLPPKMVGKPVNFMEEDILGPLPPPLNEEEEE--AEEEEEEEEEEE------- 164
++ + E + P +E+EEE A EEEEEEEEEE
Sbjct: 1099 TVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEEMVAEESM 1158
Query: 165 ---NPVHKIPDSHEITLKHGTKTVSALGLD 191
P D E L G V +LG++
Sbjct: 1159 ASAGPEDFEQDGEEAALAPGAPAVDSLGME 1188
Score = 35.0 bits (79), Expect = 0.22
Identities = 31/100 (31%), Positives = 42/100 (42%), Gaps = 9/100 (9%)
Query: 75 RQNEDIEPTSSRSNVVRDCSKSSSRDTSSSESEQSSDSSDDELIGPPLPPKMVG------ 128
++ E + TSS S S + SE E+ D +D PK VG
Sbjct: 965 KRKEPPDTTSSGDQKRLRPSTSVDEEDEESERERDRDMADTPCELAKRDPKGVGVRRRPA 1024
Query: 129 KPVNFM---EEDILGPLPPPLNEEEEEAEEEEEEEEEEEN 165
+P+ EED L EEE E EEEEEEE+++
Sbjct: 1025 RPLELDSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDD 1064
>gi|211904182 DDB1 and CUL4 associated factor 8-like 2 [Homo
sapiens]
Length = 631
Score = 50.8 bits (120), Expect = 4e-06
Identities = 76/318 (23%), Positives = 121/318 (38%), Gaps = 42/318 (13%)
Query: 185 VSALGLDPSGARLVTGGYDYDVKFWDFAGMDASFKAFRSLQPCECHQIKSLQYSNTGDMI 244
V+ + + G RL + G D V WD+ F S Q K L N GD
Sbjct: 231 VNTVHFNQRGTRLASSGDDLKVIVWDWVRQRPVLN-FESGHTNNVFQAKFLP--NCGDST 287
Query: 245 LVVSGSSQAKVIDRDG-FEVMECIKGDQYIVDMANTK---GHTAMLHTGSWHPKIKGEFM 300
L + RDG V E I + NTK H H + P +F+
Sbjct: 288 LAMCA--------RDGQVRVAELINASYF----NNTKCVAQHRGPAHKLALEPDSPYKFL 335
Query: 301 TCSNDATVRTWEVENPKKQKSVFKPRTMQGKKVIPTTCTYSRDGNLIAAACQNGSIQIWD 360
T DA V T ++ + V R K + T + A Q+ ++I+D
Sbjct: 336 TSGEDAVVFTIDLRQDRPASKVVVTRENDKKVGLYTITVNPANTYQFAVGGQDQFVRIYD 395
Query: 361 R-------NLTVHPKF--HYKQAHDSGTDTSCVTFSYDGNVLASRGGDDSLKLW-----D 406
+ N V KF H+ D T+ +CV +S+DG L + DD + L+ D
Sbjct: 396 QRKIDKKENNGVLKKFTPHHLVNCDFPTNITCVVYSHDGTELLASYNDDDIYLFNSSHSD 455
Query: 407 IRQFNKPLFSASGLPTMFPMTDCCFSPDDKLIVTGTSIQRGCGSGKLVFFERRTFQRVYE 466
Q++K T+ + + P + +V+G+ G + F+E+ + Q +
Sbjct: 456 GAQYSKRFKGHRNNTTVKGVN--FYGPRSEFVVSGSD------CGHIFFWEKSSCQIIQF 507
Query: 467 IDITDASVVRCLW-HPKL 483
+ + + CL HP L
Sbjct: 508 LKGSREGTINCLEPHPYL 525
Score = 38.1 bits (87), Expect = 0.026
Identities = 41/127 (32%), Positives = 53/127 (41%), Gaps = 21/127 (16%)
Query: 65 EEMNREKELRRQNEDIEPTSSRSNVVRDCSKSSSRD--------TSSSESEQSSDSSDDE 116
EE + + DI+ +S +V S SRD T + S+Q S S D E
Sbjct: 24 EEQSGAVAATEASSDIDIATSELSVTVTGDGSDSRDGGFPNDASTENRSSDQESASEDIE 83
Query: 117 L-----------IGPPL-PPKMVGKPVNFMEEDILGPLPPPLNEEEEEAEEEEEEEEEEE 164
L G L +VG+ EE+ + EEEEE EEEEEEEEEEE
Sbjct: 84 LESLEDFEHFLMSGESLFHYPLVGEEETEREEED-EEIQEEGGEEEEEEEEEEEEEEEEE 142
Query: 165 NPVHKIP 171
+ P
Sbjct: 143 EEEEEQP 149
>gi|7657439 PCAF associated factor 65 beta isoform a [Homo sapiens]
Length = 589
Score = 50.8 bits (120), Expect = 4e-06
Identities = 34/128 (26%), Positives = 59/128 (46%), Gaps = 11/128 (8%)
Query: 281 GHTAMLHTGSWHPKIKGEFMTCSNDATVRTWEVENPKKQKSVFKPRTMQGKKVIPTTCTY 340
GH A + +HP T S D TVR W + R G + + +
Sbjct: 424 GHLADVDCVKFHPN-SNYLATGSTDKTVRLWSAQQGNSV------RLFTGHRGPVLSLAF 476
Query: 341 SRDGNLIAAACQNGSIQIWDRNLTVHPKFHYKQAHDSGTDTSCVTFSYDGNVLASRGGDD 400
S +G +A+A ++ +++WD + YK+ + + +TFS D ++AS D+
Sbjct: 477 SPNGKYLASAGEDQRLKLWD----LASGTLYKELRGHTDNITSLTFSPDSGLIASASMDN 532
Query: 401 SLKLWDIR 408
S+++WDIR
Sbjct: 533 SVRVWDIR 540
Score = 37.4 bits (85), Expect = 0.044
Identities = 37/173 (21%), Positives = 68/173 (39%), Gaps = 16/173 (9%)
Query: 275 DMANTKGHTAMLHTGSWHPKIKGEFMTCSNDATVRTWEVENPKKQKSVFKPRTMQGKKVI 334
+M +GH +++ + G ++CS D ++R W++ S QG
Sbjct: 334 EMKILRGHCGPVYSTRFLADSSG-LLSCSEDMSIRYWDLG------SFTNTVLYQGHAYP 386
Query: 335 PTTCTYSRDGNLIAAACQNGSIQIWDRNLTVHPKFHYKQAHDSGTDTSCVTFSYDGNVLA 394
S A+ + + ++W + T + + D CV F + N LA
Sbjct: 387 VWDLDISPYSLYFASGSHDRTARLWSFDRTYPLRIYAGHL----ADVDCVKFHPNSNYLA 442
Query: 395 SRGGDDSLKLWDIRQFNK-PLFSASGLPTMFPMTDCCFSPDDKLIVTGTSIQR 446
+ D +++LW +Q N LF+ P+ FSP+ K + + QR
Sbjct: 443 TGSTDKTVRLWSAQQGNSVRLFTGH----RGPVLSLAFSPNGKYLASAGEDQR 491
Score = 30.4 bits (67), Expect = 5.4
Identities = 27/119 (22%), Positives = 43/119 (36%), Gaps = 14/119 (11%)
Query: 185 VSALGLDPSGARLVTGGYDYDVKFWDFAGMDASFKAFRSLQPCECHQIKSLQYSNTGDMI 244
V +L P+G L + G D +K WD A +K R I SL +S +I
Sbjct: 471 VLSLAFSPNGKYLASAGEDQRLKLWDLAS-GTLYKELRG----HTDNITSLTFSPDSGLI 525
Query: 245 LVVSGSSQAKVIDRDGFEVMECIKGDQYIVDMANTKGHTAMLHTGSWHPKIKGEFMTCS 303
S + +V D I+ + ++TG + +FM C+
Sbjct: 526 ASASMDNSVRVWD---------IRNTYCSAPADGSSSELVGVYTGQMSNVLSVQFMACN 575
>gi|23199987 WD repeat domain 5B [Homo sapiens]
Length = 330
Score = 50.8 bits (120), Expect = 4e-06
Identities = 55/249 (22%), Positives = 99/249 (39%), Gaps = 31/249 (12%)
Query: 158 EEEEEEENPVHKIPDSHEITLKHGTKTVSALGLDPSGARLVTGGYDYDVKFWDFAGMDAS 217
+ +E ENP + + + TL T+ VS++ P+G L + D + W D
Sbjct: 21 QSKEVPENPNYAL----KCTLVGHTEAVSSVKFSPNGEWLASSSADRLIIIW--GAYDGK 74
Query: 218 FKAFRSLQPCECHQIKSLQYSNTGDMILVVSGSSQAKVIDRDGFEVMECIKGDQYIVDMA 277
++ E I + +S+ ++ S K+ D + ++ +KG V
Sbjct: 75 YEKTLYGHNLE---ISDVAWSSDSSRLVSASDDKTLKLWDVRSGKCLKTLKGHSNYVFCC 131
Query: 278 NTKGHTAMLHTGSWHPKIKGEFMTCSNDATVRTWEVENPKKQKSVFKPRTMQGKKVIPTT 337
N + ++ +GS+ D TV+ WEV+ K K T+ +
Sbjct: 132 NFNPPSNLIISGSF-------------DETVKIWEVKTGKCLK------TLSAHSDPVSA 172
Query: 338 CTYSRDGNLIAAACQNGSIQIWDRNLTVHPKFHYKQAHDSGTDTSCVTFSYDGNVLASRG 397
++ G+LI + +G +IWD + D S V FS +G + +
Sbjct: 173 VHFNCSGSLIVSGSYDGLCRIWD---AASGQCLKTLVDDDNPPVSFVKFSPNGKYILTAT 229
Query: 398 GDDSLKLWD 406
D++LKLWD
Sbjct: 230 LDNTLKLWD 238
Score = 39.7 bits (91), Expect = 0.009
Identities = 31/116 (26%), Positives = 54/116 (46%), Gaps = 7/116 (6%)
Query: 327 TMQGKKVIPTTCTYSRDGNLIAAACQNGSIQIWDRNLTVHPKFHYKQAHDSGTDTSCVTF 386
T+ G ++ +S +G +A++ + I IW + + K + + S V +
Sbjct: 36 TLVGHTEAVSSVKFSPNGEWLASSSADRLIIIWG----AYDGKYEKTLYGHNLEISDVAW 91
Query: 387 SYDGNVLASRGGDDSLKLWDIRQFNKPLFSASGLPTMFPMTDCCFSPDDKLIVTGT 442
S D + L S D +LKLWD+R K L + G + C F+P LI++G+
Sbjct: 92 SSDSSRLVSASDDKTLKLWDVRS-GKCLKTLKGHSNY--VFCCNFNPPSNLIISGS 144
Score = 32.7 bits (73), Expect = 1.1
Identities = 43/191 (22%), Positives = 81/191 (42%), Gaps = 28/191 (14%)
Query: 177 TLKHGTKTVSALGLDPSGARLVTGGYDYDVKFWDFAGMDASFKAFRSLQPCECHQIKSLQ 236
TL + VSA+ + SG+ +V+G YD + WD AS + ++L + + ++
Sbjct: 162 TLSAHSDPVSAVHFNCSGSLIVSGSYDGLCRIWD----AASGQCLKTLVDDDNPPVSFVK 217
Query: 237 YSNTGDMILVVSGSSQAKVIDRDGFEVMECI---KGDQYIVDMANTKGHTAMLHTGSWHP 293
+S G IL + + K+ D ++ K ++Y + AN + G W
Sbjct: 218 FSPNGKYILTATLDNTLKLWDYSRGRCLKTYTGHKNEKYCI-FANFS-----VTGGKW-- 269
Query: 294 KIKGEFMTCSNDATVRTWEVENPKKQKSVFKPRTMQGKKVIPTTCTYSRDGNLIAAAC-- 351
++ S D V W ++ K + + +QG + + NLIA+A
Sbjct: 270 -----IVSGSEDNLVYIWNLQT----KEIV--QKLQGHTDVVISAACHPTENLIASAALE 318
Query: 352 QNGSIQIWDRN 362
+ +I++W N
Sbjct: 319 NDKTIKLWMSN 329
>gi|30089954 H326 [Homo sapiens]
Length = 597
Score = 50.8 bits (120), Expect = 4e-06
Identities = 109/593 (18%), Positives = 207/593 (34%), Gaps = 108/593 (18%)
Query: 50 AVERSRKTLEAREKEEEMNREKELRRQNEDIEPTSSRSNVVRDCSKSSSRDTSSSESEQS 109
++ S + + E+ E + E+ + + T R ++S DT SS ++
Sbjct: 18 SLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTSTESRGTDTESSGEDKD 77
Query: 110 SDSSDDELIGPPLPPKMVGKPVNFMEEDILGPLPPPLNEEEEEAEEEEEEEEEEENPVHK 169
SDS +D + +E+ + EEEEE EEE+ + ++
Sbjct: 78 SDSMEDT------------GHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRKRANR 125
Query: 170 IPDSHE---------------------------------------------------ITL 178
DS + L
Sbjct: 126 DQDSSDDERALEDWVSSETSALPRPRWQALPALRERELGSSARFVYEACGARVFVQRFRL 185
Query: 179 KHG----TKTVSALGLDPSGARLVTGGYDYDVKFWDFAGMDASFKAFRSLQPCECHQIKS 234
+HG T V+ L + G L +G D V WD+ F S Q K
Sbjct: 186 QHGLEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLD-FESGHKSNVFQAKF 244
Query: 235 LQYSNTGDMILVVSG-SSQAKVIDRDGFEVMECIKGDQYIVDMANTKGHTAMLHTGSWHP 293
L N+GD L + Q +V + +C K + + H H + P
Sbjct: 245 LP--NSGDSTLAMCARDGQVRVAE---LSATQCCKNTKRVAQ------HKGASHKLALEP 293
Query: 294 KIKGEFMTCSNDATVRTWEVENPKKQKSVFKPRTMQGKKVIPTTCTYSRDGNLIAAACQN 353
F++ DA V T ++ + + + + K + T + + A ++
Sbjct: 294 DSPCTFLSAGEDAVVFTIDLRQDRPASKLVVTKEKEKKVGLYTIYVNPANTHQFAVGGRD 353
Query: 354 GSIQIWDR-------NLTVHPKF--HYKQAHDSGTDTSCVTFSYDGNVLASRGGDDSLKL 404
++I+D+ N V KF H+ +S + +C+ +S+DG L + D+ + L
Sbjct: 354 QFVRIYDQRKIDENENNGVLKKFCPHHLVNSESKANITCLVYSHDGTELLASYNDEDIYL 413
Query: 405 W-----DIRQFNKPLFSASGLPTMFPMTDCCFSPDDKLIVTGTSIQRGCGSGKLVFFERR 459
+ D Q+ K T+ + + P + +V+G+ G + +E+
Sbjct: 414 FNSSHSDGAQYVKRYKGHRNNATVKGVN--FYGPKSEFVVSGSD------CGHIFLWEKS 465
Query: 460 TFQRVYEIDITDASVVRCLW-HPKLNQIMVGTGNGLAKVY---YDPNKSQRGAKLCVVKT 515
+ Q + ++ VV CL HP L + + K++ + + G K V+K
Sbjct: 466 SCQIIQFMEGDKGGVVNCLEPHPHLPVLATSGLDHDVKIWAPTAEASTELTGLK-DVIKK 524
Query: 516 QRKAKQAETLTQDYIITPHAL-PMFREPRQRSTRKQLEKDRLDPLKSHKPEPP 567
++ + ++L Q + H L + RQR ++ + + + E P
Sbjct: 525 NKRERDEDSLHQTDLFDSHMLWFLMHHLRQRRHHRRWREPGVGATDADSDESP 577
>gi|109948304 smu-1 suppressor of mec-8 and unc-52 homolog [Homo
sapiens]
Length = 513
Score = 50.4 bits (119), Expect = 5e-06
Identities = 59/290 (20%), Positives = 121/290 (41%), Gaps = 35/290 (12%)
Query: 100 DTSSSESEQSSDSS----DDELIGPPLPPKMVGKPVNFMEEDILGPLPPPLNEEEEEAEE 155
D SS E +++ + + ++ P ++G+ + + + G LPP + + +
Sbjct: 134 DGSSKEKRRAAIAQALAGEVSVVPPSRLMALLGQALKWQQHQ--GLLPPGMTIDLFRGKA 191
Query: 156 EEEEEEEEENPVHKIPDSHEITLKHGTKT-VSALGLDPSGARLVTGGYDYDVKFWDFAG- 213
++ EEE K P +K G K+ V P G LVTG D ++ W+F
Sbjct: 192 AVKDVEEE-----KFPTQLSRHIKFGQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTG 246
Query: 214 ---MDASFKAFRSLQPCECHQIKSLQYSNTGDMILVVSGSSQAKVIDRDGFEVMECIKGD 270
D ++A + + + + +S +M+ + + KV + +C++
Sbjct: 247 KIRKDLKYQAQDNFMMMD-DAVLCMCFSRDTEMLATGAQDGKIKVWK---IQSGQCLRR- 301
Query: 271 QYIVDMANTKGHTAMLHTGSWHPKIKGEFMTCSNDATVRTWEVENPKKQKSVFKPRTMQG 330
+ A++KG T + + K + ++ S D T+R +++ K K +G
Sbjct: 302 ---FERAHSKGVTCLSFS-----KDSSQILSASFDQTIRIHGLKSGKTLKE------FRG 347
Query: 331 KKVIPTTCTYSRDGNLIAAACQNGSIQIWDRNLTVHPKFHYKQAHDSGTD 380
T+++DG+ I +A +G+++IW+ T +GTD
Sbjct: 348 HSSFVNEATFTQDGHYIISASSDGTVKIWNMKTTECSNTFKSLGSTAGTD 397
>gi|4505731 peroxisomal biogenesis factor 7 [Homo sapiens]
Length = 323
Score = 50.1 bits (118), Expect = 7e-06
Identities = 53/218 (24%), Positives = 93/218 (42%), Gaps = 26/218 (11%)
Query: 197 LVTGGYDYDVKFWDFAGMDASFKAFRSLQPCECHQIKSLQYSNTGDMILVVSGSSQAKVI 256
L+T D ++ WD A + ++ ++ S+ +S T LVVSGS V
Sbjct: 83 LITCSGDGSLQLWDTAKAAGPLQVYKE----HAQEVYSVDWSQTRGEQLVVSGSWDQTV- 137
Query: 257 DRDGFEVMECIKGDQYIVDMANTKGHTAMLHTGSWHPKIKGEFMTCSNDATVRTWEVENP 316
++ + G + +GH +++++ W P I G F + S D T+R W+V+
Sbjct: 138 -----KLWDPTVGKS----LCTFRGHESIIYSTIWSPHIPGCFASASGDQTLRIWDVKAA 188
Query: 317 KKQKSVFKPRTMQGKKVIPTTCTYSRDGNLIAAACQNGSIQIWDRNLTVHPKFHYKQAHD 376
+ + Q + + C Y+ NL+ + S++ WD P F H
Sbjct: 189 GVRIVI---PAHQAEILSCDWCKYNE--NLLVTGAVDCSLRGWDLRNVRQPVFEL-LGHT 242
Query: 377 SGTDTSCVTFS-YDGNVLASRGGDDSLKLWDIRQFNKP 413
V FS + +VLAS D +++ W+ F+KP
Sbjct: 243 YAIRR--VKFSPFHASVLASCSYDFTVRFWN---FSKP 275
Score = 40.0 bits (92), Expect = 0.007
Identities = 25/119 (21%), Positives = 53/119 (44%), Gaps = 6/119 (5%)
Query: 290 SWHPKIKGEFMTCSNDATVRTWEVENPKKQKSVFKPRTMQGKKVIPTTCTYSRDGNLIAA 349
+W + +TCS D +++ W+ V+K ++V + +R L+ +
Sbjct: 74 TWSENNEHVLITCSGDGSLQLWDTAKAAGPLQVYKE---HAQEVYSVDWSQTRGEQLVVS 130
Query: 350 ACQNGSIQIWDRNLTVHPKFHYKQAHDSGTDTSCVTFSYDGNVLASRGGDDSLKLWDIR 408
+ ++++WD TV + H+S S + + AS GD +L++WD++
Sbjct: 131 GSWDQTVKLWDP--TVGKSLCTFRGHES-IIYSTIWSPHIPGCFASASGDQTLRIWDVK 186
Score = 39.7 bits (91), Expect = 0.009
Identities = 42/153 (27%), Positives = 67/153 (43%), Gaps = 32/153 (20%)
Query: 272 YIVDMANTKGHTAMLHTGSWHPKIKGEFMTCSNDATVRTWEVENPKKQKSVFKPRTMQG- 330
Y VD + T+G ++ +GSW D TV+ W+ P KS+ T +G
Sbjct: 115 YSVDWSQTRGEQLVV-SGSW-------------DQTVKLWD---PTVGKSLC---TFRGH 154
Query: 331 KKVIPTTCTYSRDGNLIAAACQNGSIQIWDRNLT----VHPKFHYKQAHDSGTDTSCVTF 386
+ +I +T A+A + +++IWD V P AH + SC
Sbjct: 155 ESIIYSTIWSPHIPGCFASASGDQTLRIWDVKAAGVRIVIP------AHQAEI-LSCDWC 207
Query: 387 SYDGNVLASRGGDDSLKLWDIRQFNKPLFSASG 419
Y+ N+L + D SL+ WD+R +P+F G
Sbjct: 208 KYNENLLVTGAVDCSLRGWDLRNVRQPVFELLG 240
>gi|113865883 WD repeat domain 38 [Homo sapiens]
Length = 314
Score = 50.1 bits (118), Expect = 7e-06
Identities = 65/299 (21%), Positives = 115/299 (38%), Gaps = 52/299 (17%)
Query: 179 KHGTKTVSALGLDPSGARLVTGGYDYDVKFWDFAGMDASFKAFRSLQPCECHQIKSLQYS 238
+HG + V++ P G L+TG D V W+ ++ P +K ++S
Sbjct: 19 QHGGE-VNSSAFSPDGQMLLTGSEDGCVYGWETRSGQLLWRLGGHTGP-----VKFCRFS 72
Query: 239 NTGDMILVVSGSSQAKVIDRDGFEVMECIKGDQYIVDMANTKGHTAMLHTGSWHPKI--- 295
G + S ++ D + + +KG Q V+ + + L +G W ++
Sbjct: 73 PDGHLFASASCDCTVRLWDVARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWDKRVMLW 132
Query: 296 ---KGEFM-----------------------TCSNDATVRTWEVENPKKQKSVFKPRTMQ 329
G+ + T S D+TV W++ + + ++
Sbjct: 133 DVQSGQMLRLLVGHRDSIQSSDFSPTVNCLATGSWDSTVHIWDL---RMVTPAVSHQALE 189
Query: 330 GKKVIPTTCTYSRDGNLIAAACQNGSIQIWD---RNLTVHPKFHYKQAHDSGTDTSCVTF 386
G + YS G L+A+ + +I IW +L + K H T + F
Sbjct: 190 GHSANISCLCYSASG-LLASGSWDKTIHIWKPTTSSLLIQLKGHV-------TWVKSIAF 241
Query: 387 SYDGNVLASRGGDDSLKLWDIRQFNKPLFSASGLPTMFPMTDCCFSPDDKLIVTGTSIQ 445
S D LAS G +K+WD K L + G+ + C F+PD K++V+G + Q
Sbjct: 242 SPDELWLASAGYSRMVKVWDCNT-GKCLETLKGVLDV--AHTCAFTPDGKILVSGAADQ 297
>gi|4557515 damage-specific DNA binding protein 2 [Homo sapiens]
Length = 427
Score = 49.3 bits (116), Expect = 1e-05
Identities = 58/265 (21%), Positives = 89/265 (33%), Gaps = 74/265 (27%)
Query: 290 SWHPKIKGEFMTCSNDATVRTWEV---ENPKKQKSVFKPRTMQGKKVIP----------- 335
+WHP S + W + P K + ++ G K P
Sbjct: 118 AWHPTHPSTVAVGSKGGDIMLWNFGIKDKPTFIKGIGAGGSITGLKFNPLNTNQFYASSM 177
Query: 336 --TTCTYSRDGNLIAAACQNGSIQIWDRNLTVHP-------------------------- 367
TT GN++ + +I IW +L V
Sbjct: 178 EGTTRLQDFKGNILRVFASSDTINIWFCSLDVSASSRMVVTGDNVGNVILLNMDGKELWN 237
Query: 368 -KFHYKQAHDSGTDTSCVTFSYDGNVLASRGGDDSLKLWDIRQFNKPLFSASGLPTMFPM 426
+ H K+ + C F LA+ D ++K+WD+RQ LP P+
Sbjct: 238 LRMHKKKVTHVALNPCCDWF------LATASVDQTVKIWDLRQVRGKASFLYSLPHRHPV 291
Query: 427 TDCCFSPDDKLIVTG---------TSIQRGCGSGKLVFFERRTFQRVYEIDITDASVVRC 477
CFSPD ++T ++ Q C G L+ R FQ + + ++
Sbjct: 292 NAACFSPDGARLLTTDQKSEIRVYSASQWDCPLG-LIPHPHRHFQHL--------TPIKA 342
Query: 478 LWHPKLNQIMVGTGNGLAKVYYDPN 502
WHP+ N I+VG Y DPN
Sbjct: 343 AWHPRYNLIVVGR-------YPDPN 360
>gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens]
Length = 369
Score = 49.3 bits (116), Expect = 1e-05
Identities = 81/403 (20%), Positives = 148/403 (36%), Gaps = 54/403 (13%)
Query: 168 HKIPDSHEITLKHGTKTVSALGLDPSGARLVTGGYDYDVKFW--DFAGMDASFKAFRSLQ 225
H P S V+ + PSG L +G D V+ W + G F+A +
Sbjct: 9 HMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTA-- 66
Query: 226 PCECHQIKSLQYSNTGDMILVVSGSSQAKV--IDRDGFEVMECIKGDQYIVDMANTKGHT 283
++S+ + + G + S KV R F + + H
Sbjct: 67 -----TVRSVHFCSDGQSFVTASDDKTVKVWATHRQKF--------------LFSLSQHI 107
Query: 284 AMLHTGSWHPKIKGEFMTCSNDATVRTWEVENPKKQKSVFKPRTMQGKKVIPTTCTYSRD 343
+ + P + ++ S+D TV+ W+ K + G V T +
Sbjct: 108 NWVRCAKFSPDGR-LIVSASDDKTVKLWD----KSSRECVHSYCEHGGFV--TYVDFHPS 160
Query: 344 GNLIAAACQNGSIQIWDRNLTVHPKFHYKQAHDSGTDTSCVTFSYDGNVLASRGGDDSLK 403
G IAAA + ++++WD + H + Q H + + ++F GN L + D +LK
Sbjct: 161 GTCIAAAGMDNTVKVWD--VRTHRLLQHYQLHSAAVNG--LSFHPSGNYLITASSDSTLK 216
Query: 404 LWDIRQFNKPLFSASGLPTMFPMTDCCFSPDDKLIVTGTSIQRGCGSGKLVFFERRTFQR 463
+ D+ + + L++ G P T FS + +G GS + V + F
Sbjct: 217 ILDLME-GRLLYTLHG--HQGPATTVAFSRTGEYFASG-------GSDEQVMVWKSNFDI 266
Query: 464 VYEIDIT-----DASVVRCLWH-PKLN-QIMVGTGNGLAKVYYDPNKSQRGAKLCVVKTQ 516
V ++T A++ + + P+++ + G G + V P + + +
Sbjct: 267 VDHGEVTKVPRPPATLASSMGNLPEVDFPVPPGRGRSVESVQSQPQEPVSVPQTLTSTLE 326
Query: 517 RKAKQAETLTQDYIITPHALPMFREP-RQRSTRKQLEKDRLDP 558
Q + LTQ I L + + +Q +QL R P
Sbjct: 327 HIVGQLDVLTQTVSILEQRLTLTEDKLKQCLENQQLIMQRATP 369
>gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens]
Length = 407
Score = 49.3 bits (116), Expect = 1e-05
Identities = 81/403 (20%), Positives = 148/403 (36%), Gaps = 54/403 (13%)
Query: 168 HKIPDSHEITLKHGTKTVSALGLDPSGARLVTGGYDYDVKFW--DFAGMDASFKAFRSLQ 225
H P S V+ + PSG L +G D V+ W + G F+A +
Sbjct: 47 HMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTA-- 104
Query: 226 PCECHQIKSLQYSNTGDMILVVSGSSQAKV--IDRDGFEVMECIKGDQYIVDMANTKGHT 283
++S+ + + G + S KV R F + + H
Sbjct: 105 -----TVRSVHFCSDGQSFVTASDDKTVKVWATHRQKF--------------LFSLSQHI 145
Query: 284 AMLHTGSWHPKIKGEFMTCSNDATVRTWEVENPKKQKSVFKPRTMQGKKVIPTTCTYSRD 343
+ + P + ++ S+D TV+ W+ K + G V T +
Sbjct: 146 NWVRCAKFSPDGR-LIVSASDDKTVKLWD----KSSRECVHSYCEHGGFV--TYVDFHPS 198
Query: 344 GNLIAAACQNGSIQIWDRNLTVHPKFHYKQAHDSGTDTSCVTFSYDGNVLASRGGDDSLK 403
G IAAA + ++++WD + H + Q H + + ++F GN L + D +LK
Sbjct: 199 GTCIAAAGMDNTVKVWD--VRTHRLLQHYQLHSAAVNG--LSFHPSGNYLITASSDSTLK 254
Query: 404 LWDIRQFNKPLFSASGLPTMFPMTDCCFSPDDKLIVTGTSIQRGCGSGKLVFFERRTFQR 463
+ D+ + + L++ G P T FS + +G GS + V + F
Sbjct: 255 ILDLME-GRLLYTLHG--HQGPATTVAFSRTGEYFASG-------GSDEQVMVWKSNFDI 304
Query: 464 VYEIDIT-----DASVVRCLWH-PKLN-QIMVGTGNGLAKVYYDPNKSQRGAKLCVVKTQ 516
V ++T A++ + + P+++ + G G + V P + + +
Sbjct: 305 VDHGEVTKVPRPPATLASSMGNLPEVDFPVPPGRGRSVESVQSQPQEPVSVPQTLTSTLE 364
Query: 517 RKAKQAETLTQDYIITPHALPMFREP-RQRSTRKQLEKDRLDP 558
Q + LTQ I L + + +Q +QL R P
Sbjct: 365 HIVGQLDVLTQTVSILEQRLTLTEDKLKQCLENQQLIMQRATP 407
Score = 29.6 bits (65), Expect = 9.2
Identities = 17/80 (21%), Positives = 36/80 (45%), Gaps = 4/80 (5%)
Query: 326 RTMQGKKVIPTTCTYSRDGNLIAAACQNGSIQIWDRNLTVHPKFHYKQAHDSGTDTSCVT 385
R +G + T +S + +A+ + + +W + P+ + +CV
Sbjct: 13 RHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWH----MKPQSRAYRFTGHKDAVTCVN 68
Query: 386 FSYDGNVLASRGGDDSLKLW 405
FS G++LAS D ++++W
Sbjct: 69 FSPSGHLLASGSRDKTVRIW 88
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.130 0.387
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,188,961
Number of Sequences: 37866
Number of extensions: 1450293
Number of successful extensions: 26749
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 465
Number of HSP's successfully gapped in prelim test: 576
Number of HSP's that attempted gapping in prelim test: 13296
Number of HSP's gapped (non-prelim): 7580
length of query: 654
length of database: 18,247,518
effective HSP length: 109
effective length of query: 545
effective length of database: 14,120,124
effective search space: 7695467580
effective search space used: 7695467580
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.