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Search of human proteins with 89191868
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|89191868 von Willebrand factor preproprotein [Homo sapiens]
(2813 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|89191868 von Willebrand factor preproprotein [Homo sapiens] 5980 0.0
gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens] 775 0.0
gi|169202626 PREDICTED: similar to mucin 5, partial [Homo sapiens] 763 0.0
gi|161019170 mucin 5AC [Homo sapiens] 761 0.0
gi|116284392 mucin 2 precursor [Homo sapiens] 753 0.0
gi|239755545 PREDICTED: otogelin isoform 1 [Homo sapiens] 654 0.0
gi|239755543 PREDICTED: otogelin isoform 2 [Homo sapiens] 654 0.0
gi|239749989 PREDICTED: otogelin isoform 2 [Homo sapiens] 654 0.0
gi|239749987 PREDICTED: otogelin isoform 1 [Homo sapiens] 654 0.0
gi|239744300 PREDICTED: otogelin isoform 2 [Homo sapiens] 654 0.0
gi|239744298 PREDICTED: otogelin isoform 1 [Homo sapiens] 654 0.0
gi|134031945 SCO-spondin [Homo sapiens] 625 e-178
gi|239755901 PREDICTED: chromosome 12 open reading frame 64 [Hom... 578 e-164
gi|239750386 PREDICTED: chromosome 12 open reading frame 64 [Hom... 578 e-164
gi|239744688 PREDICTED: hypothetical protein LOC283310 [Homo sap... 578 e-164
gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens] 569 e-161
gi|151301154 mucin 6, gastric [Homo sapiens] 557 e-158
gi|239750277 PREDICTED: hypothetical protein XP_002347351 [Homo ... 511 e-144
gi|239744587 PREDICTED: hypothetical protein XP_002343203 [Homo ... 511 e-144
gi|239757286 PREDICTED: similar to Fc fragment of IgG binding pr... 314 7e-85
gi|239751787 PREDICTED: hypothetical protein XP_002348012 [Homo ... 314 7e-85
gi|154146262 Fc fragment of IgG binding protein [Homo sapiens] 314 7e-85
gi|239757282 PREDICTED: similar to Fc fragment of IgG binding pr... 305 4e-82
gi|16554449 zonadhesin isoform 3 [Homo sapiens] 290 1e-77
gi|27881494 zonadhesin isoform 6 [Homo sapiens] 290 1e-77
gi|134268640 tectorin alpha precursor [Homo sapiens] 270 1e-71
gi|239755776 PREDICTED: similar to Mucin-19 [Homo sapiens] 249 3e-65
gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens] 226 3e-58
gi|239755460 PREDICTED: similar to mucin, partial [Homo sapiens] 206 3e-52
gi|239757284 PREDICTED: similar to Fc fragment of IgG binding pr... 192 3e-48
>gi|89191868 von Willebrand factor preproprotein [Homo sapiens]
Length = 2813
Score = 5980 bits (15513), Expect = 0.0
Identities = 2813/2813 (100%), Positives = 2813/2813 (100%)
Query: 1 MIPARFAGVLLALALILPGTLCAEGTRGRSSTARCSLFGSDFVNTFDGSMYSFAGYCSYL 60
MIPARFAGVLLALALILPGTLCAEGTRGRSSTARCSLFGSDFVNTFDGSMYSFAGYCSYL
Sbjct: 1 MIPARFAGVLLALALILPGTLCAEGTRGRSSTARCSLFGSDFVNTFDGSMYSFAGYCSYL 60
Query: 61 LAGGCQKRSFSIIGDFQNGKRVSLSVYLGEFFDIHLFVNGTVTQGDQRVSMPYASKGLYL 120
LAGGCQKRSFSIIGDFQNGKRVSLSVYLGEFFDIHLFVNGTVTQGDQRVSMPYASKGLYL
Sbjct: 61 LAGGCQKRSFSIIGDFQNGKRVSLSVYLGEFFDIHLFVNGTVTQGDQRVSMPYASKGLYL 120
Query: 121 ETEAGYYKLSGEAYGFVARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTL 180
ETEAGYYKLSGEAYGFVARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTL
Sbjct: 121 ETEAGYYKLSGEAYGFVARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTL 180
Query: 181 TSDPYDFANSWALSSGEQWCERASPPSSSCNISSGEMQKGLWEQCQLLKSTSVFARCHPL 240
TSDPYDFANSWALSSGEQWCERASPPSSSCNISSGEMQKGLWEQCQLLKSTSVFARCHPL
Sbjct: 181 TSDPYDFANSWALSSGEQWCERASPPSSSCNISSGEMQKGLWEQCQLLKSTSVFARCHPL 240
Query: 241 VDPEPFVALCEKTLCECAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGME 300
VDPEPFVALCEKTLCECAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGME
Sbjct: 241 VDPEPFVALCEKTLCECAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGME 300
Query: 301 YRQCVSPCARTCQSLHINEMCQERCVDGCSCPEGQLLDEGLCVESTECPCVHSGKRYPPG 360
YRQCVSPCARTCQSLHINEMCQERCVDGCSCPEGQLLDEGLCVESTECPCVHSGKRYPPG
Sbjct: 301 YRQCVSPCARTCQSLHINEMCQERCVDGCSCPEGQLLDEGLCVESTECPCVHSGKRYPPG 360
Query: 361 TSLSRDCNTCICRNSQWICSNEECPGECLVTGQSHFKSFDNRYFTFSGICQYLLARDCQD 420
TSLSRDCNTCICRNSQWICSNEECPGECLVTGQSHFKSFDNRYFTFSGICQYLLARDCQD
Sbjct: 361 TSLSRDCNTCICRNSQWICSNEECPGECLVTGQSHFKSFDNRYFTFSGICQYLLARDCQD 420
Query: 421 HSFSIVIETVQCADDRDAVCTRSVTVRLPGLHNSLVKLKHGAGVAMDGQDVQLPLLKGDL 480
HSFSIVIETVQCADDRDAVCTRSVTVRLPGLHNSLVKLKHGAGVAMDGQDVQLPLLKGDL
Sbjct: 421 HSFSIVIETVQCADDRDAVCTRSVTVRLPGLHNSLVKLKHGAGVAMDGQDVQLPLLKGDL 480
Query: 481 RIQHTVTASVRLSYGEDLQMDWDGRGRLLVKLSPVYAGKTCGLCGNYNGNQGDDFLTPSG 540
RIQHTVTASVRLSYGEDLQMDWDGRGRLLVKLSPVYAGKTCGLCGNYNGNQGDDFLTPSG
Sbjct: 481 RIQHTVTASVRLSYGEDLQMDWDGRGRLLVKLSPVYAGKTCGLCGNYNGNQGDDFLTPSG 540
Query: 541 LAEPRVEDFGNAWKLHGDCQDLQKQHSDPCALNPRMTRFSEEACAVLTSPTFEACHRAVS 600
LAEPRVEDFGNAWKLHGDCQDLQKQHSDPCALNPRMTRFSEEACAVLTSPTFEACHRAVS
Sbjct: 541 LAEPRVEDFGNAWKLHGDCQDLQKQHSDPCALNPRMTRFSEEACAVLTSPTFEACHRAVS 600
Query: 601 PLPYLRNCRYDVCSCSDGRECLCGALASYAAACAGRGVRVAWREPGRCELNCPKGQVYLQ 660
PLPYLRNCRYDVCSCSDGRECLCGALASYAAACAGRGVRVAWREPGRCELNCPKGQVYLQ
Sbjct: 601 PLPYLRNCRYDVCSCSDGRECLCGALASYAAACAGRGVRVAWREPGRCELNCPKGQVYLQ 660
Query: 661 CGTPCNLTCRSLSYPDEECNEACLEGCFCPPGLYMDERGDCVPKAQCPCYYDGEIFQPED 720
CGTPCNLTCRSLSYPDEECNEACLEGCFCPPGLYMDERGDCVPKAQCPCYYDGEIFQPED
Sbjct: 661 CGTPCNLTCRSLSYPDEECNEACLEGCFCPPGLYMDERGDCVPKAQCPCYYDGEIFQPED 720
Query: 721 IFSDHHTMCYCEDGFMHCTMSGVPGSLLPDAVLSSPLSHRSKRSLSCRPPMVKLVCPADN 780
IFSDHHTMCYCEDGFMHCTMSGVPGSLLPDAVLSSPLSHRSKRSLSCRPPMVKLVCPADN
Sbjct: 721 IFSDHHTMCYCEDGFMHCTMSGVPGSLLPDAVLSSPLSHRSKRSLSCRPPMVKLVCPADN 780
Query: 781 LRAEGLECTKTCQNYDLECMSMGCVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAPGE 840
LRAEGLECTKTCQNYDLECMSMGCVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAPGE
Sbjct: 781 LRAEGLECTKTCQNYDLECMSMGCVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAPGE 840
Query: 841 TVKIGCNTCVCRDRKWNCTDHVCDATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGS 900
TVKIGCNTCVCRDRKWNCTDHVCDATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGS
Sbjct: 841 TVKIGCNTCVCRDRKWNCTDHVCDATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGS 900
Query: 901 NPGTFRILVGNKGCSHPSVKCKKRVTILVEGGEIELFDGEVNVKRPMKDETHFEVVESGR 960
NPGTFRILVGNKGCSHPSVKCKKRVTILVEGGEIELFDGEVNVKRPMKDETHFEVVESGR
Sbjct: 901 NPGTFRILVGNKGCSHPSVKCKKRVTILVEGGEIELFDGEVNVKRPMKDETHFEVVESGR 960
Query: 961 YIILLLGKALSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVD 1020
YIILLLGKALSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVD
Sbjct: 961 YIILLLGKALSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVD 1020
Query: 1021 FGNSWKVSSQCADTRKVPLDSSPATCHNNIMKQTMVDSSCRILTSDVFQDCNKLVDPEPY 1080
FGNSWKVSSQCADTRKVPLDSSPATCHNNIMKQTMVDSSCRILTSDVFQDCNKLVDPEPY
Sbjct: 1021 FGNSWKVSSQCADTRKVPLDSSPATCHNNIMKQTMVDSSCRILTSDVFQDCNKLVDPEPY 1080
Query: 1081 LDVCIYDTCSCESIGDCACFCDTIAAYAHVCAQHGKVVTWRTATLCPQSCEERNLRENGY 1140
LDVCIYDTCSCESIGDCACFCDTIAAYAHVCAQHGKVVTWRTATLCPQSCEERNLRENGY
Sbjct: 1081 LDVCIYDTCSCESIGDCACFCDTIAAYAHVCAQHGKVVTWRTATLCPQSCEERNLRENGY 1140
Query: 1141 ECEWRYNSCAPACQVTCQHPEPLACPVQCVEGCHAHCPPGKILDELLQTCVDPEDCPVCE 1200
ECEWRYNSCAPACQVTCQHPEPLACPVQCVEGCHAHCPPGKILDELLQTCVDPEDCPVCE
Sbjct: 1141 ECEWRYNSCAPACQVTCQHPEPLACPVQCVEGCHAHCPPGKILDELLQTCVDPEDCPVCE 1200
Query: 1201 VAGRRFASGKKVTLNPSDPEHCQICHCDVVNLTCEACQEPGGLVVPPTDAPVSPTTLYVE 1260
VAGRRFASGKKVTLNPSDPEHCQICHCDVVNLTCEACQEPGGLVVPPTDAPVSPTTLYVE
Sbjct: 1201 VAGRRFASGKKVTLNPSDPEHCQICHCDVVNLTCEACQEPGGLVVPPTDAPVSPTTLYVE 1260
Query: 1261 DISEPPLHDFYCSRLLDLVFLLDGSSRLSEAEFEVLKAFVVDMMERLRISQKWVRVAVVE 1320
DISEPPLHDFYCSRLLDLVFLLDGSSRLSEAEFEVLKAFVVDMMERLRISQKWVRVAVVE
Sbjct: 1261 DISEPPLHDFYCSRLLDLVFLLDGSSRLSEAEFEVLKAFVVDMMERLRISQKWVRVAVVE 1320
Query: 1321 YHDGSHAYIGLKDRKRPSELRRIASQVKYAGSQVASTSEVLKYTLFQIFSKIDRPEASRI 1380
YHDGSHAYIGLKDRKRPSELRRIASQVKYAGSQVASTSEVLKYTLFQIFSKIDRPEASRI
Sbjct: 1321 YHDGSHAYIGLKDRKRPSELRRIASQVKYAGSQVASTSEVLKYTLFQIFSKIDRPEASRI 1380
Query: 1381 TLLLMASQEPQRMSRNFVRYVQGLKKKKVIVIPVGIGPHANLKQIRLIEKQAPENKAFVL 1440
TLLLMASQEPQRMSRNFVRYVQGLKKKKVIVIPVGIGPHANLKQIRLIEKQAPENKAFVL
Sbjct: 1381 TLLLMASQEPQRMSRNFVRYVQGLKKKKVIVIPVGIGPHANLKQIRLIEKQAPENKAFVL 1440
Query: 1441 SSVDELEQQRDEIVSYLCDLAPEAPPPTLPPDMAQVTVGPGLLGVSTLGPKRNSMVLDVA 1500
SSVDELEQQRDEIVSYLCDLAPEAPPPTLPPDMAQVTVGPGLLGVSTLGPKRNSMVLDVA
Sbjct: 1441 SSVDELEQQRDEIVSYLCDLAPEAPPPTLPPDMAQVTVGPGLLGVSTLGPKRNSMVLDVA 1500
Query: 1501 FVLEGSDKIGEADFNRSKEFMEEVIQRMDVGQDSIHVTVLQYSYMVTVEYPFSEAQSKGD 1560
FVLEGSDKIGEADFNRSKEFMEEVIQRMDVGQDSIHVTVLQYSYMVTVEYPFSEAQSKGD
Sbjct: 1501 FVLEGSDKIGEADFNRSKEFMEEVIQRMDVGQDSIHVTVLQYSYMVTVEYPFSEAQSKGD 1560
Query: 1561 ILQRVREIRYQGGNRTNTGLALRYLSDHSFLVSQGDREQAPNLVYMVTGNPASDEIKRLP 1620
ILQRVREIRYQGGNRTNTGLALRYLSDHSFLVSQGDREQAPNLVYMVTGNPASDEIKRLP
Sbjct: 1561 ILQRVREIRYQGGNRTNTGLALRYLSDHSFLVSQGDREQAPNLVYMVTGNPASDEIKRLP 1620
Query: 1621 GDIQVVPIGVGPNANVQELERIGWPNAPILIQDFETLPREAPDLVLQRCCSGEGLQIPTL 1680
GDIQVVPIGVGPNANVQELERIGWPNAPILIQDFETLPREAPDLVLQRCCSGEGLQIPTL
Sbjct: 1621 GDIQVVPIGVGPNANVQELERIGWPNAPILIQDFETLPREAPDLVLQRCCSGEGLQIPTL 1680
Query: 1681 SPAPDCSQPLDVILLLDGSSSFPASYFDEMKSFAKAFISKANIGPRLTQVSVLQYGSITT 1740
SPAPDCSQPLDVILLLDGSSSFPASYFDEMKSFAKAFISKANIGPRLTQVSVLQYGSITT
Sbjct: 1681 SPAPDCSQPLDVILLLDGSSSFPASYFDEMKSFAKAFISKANIGPRLTQVSVLQYGSITT 1740
Query: 1741 IDVPWNVVPEKAHLLSLVDVMQREGGPSQIGDALGFAVRYLTSEMHGARPGASKAVVILV 1800
IDVPWNVVPEKAHLLSLVDVMQREGGPSQIGDALGFAVRYLTSEMHGARPGASKAVVILV
Sbjct: 1741 IDVPWNVVPEKAHLLSLVDVMQREGGPSQIGDALGFAVRYLTSEMHGARPGASKAVVILV 1800
Query: 1801 TDVSVDSVDAAADAARSNRVTVFPIGIGDRYDAAQLRILAGPAGDSNVVKLQRIEDLPTM 1860
TDVSVDSVDAAADAARSNRVTVFPIGIGDRYDAAQLRILAGPAGDSNVVKLQRIEDLPTM
Sbjct: 1801 TDVSVDSVDAAADAARSNRVTVFPIGIGDRYDAAQLRILAGPAGDSNVVKLQRIEDLPTM 1860
Query: 1861 VTLGNSFLHKLCSGFVRICMDEDGNEKRPGDVWTLPDQCHTVTCQPDGQTLLKSHRVNCD 1920
VTLGNSFLHKLCSGFVRICMDEDGNEKRPGDVWTLPDQCHTVTCQPDGQTLLKSHRVNCD
Sbjct: 1861 VTLGNSFLHKLCSGFVRICMDEDGNEKRPGDVWTLPDQCHTVTCQPDGQTLLKSHRVNCD 1920
Query: 1921 RGLRPSCPNSQSPVKVEETCGCRWTCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQNK 1980
RGLRPSCPNSQSPVKVEETCGCRWTCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQNK
Sbjct: 1921 RGLRPSCPNSQSPVKVEETCGCRWTCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQNK 1980
Query: 1981 EQDLEVILHNGACSPGARQGCMKSIEVKHSALSVELHSDMEVTVNGRLVSVPYVGGNMEV 2040
EQDLEVILHNGACSPGARQGCMKSIEVKHSALSVELHSDMEVTVNGRLVSVPYVGGNMEV
Sbjct: 1981 EQDLEVILHNGACSPGARQGCMKSIEVKHSALSVELHSDMEVTVNGRLVSVPYVGGNMEV 2040
Query: 2041 NVYGAIMHEVRFNHLGHIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRD 2100
NVYGAIMHEVRFNHLGHIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRD
Sbjct: 2041 NVYGAIMHEVRFNHLGHIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRD 2100
Query: 2101 GTVTTDWKTLVQEWTVQRPGQTCQPILEEQCLVPDSSHCQVLLLPLFAECHKVLAPATFY 2160
GTVTTDWKTLVQEWTVQRPGQTCQPILEEQCLVPDSSHCQVLLLPLFAECHKVLAPATFY
Sbjct: 2101 GTVTTDWKTLVQEWTVQRPGQTCQPILEEQCLVPDSSHCQVLLLPLFAECHKVLAPATFY 2160
Query: 2161 AICQQDSCHQEQVCEVIASYAHLCRTNGVCVDWRTPDFCAMSCPPSLVYNHCEHGCPRHC 2220
AICQQDSCHQEQVCEVIASYAHLCRTNGVCVDWRTPDFCAMSCPPSLVYNHCEHGCPRHC
Sbjct: 2161 AICQQDSCHQEQVCEVIASYAHLCRTNGVCVDWRTPDFCAMSCPPSLVYNHCEHGCPRHC 2220
Query: 2221 DGNVSSCGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWVPDHQPCQI 2280
DGNVSSCGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWVPDHQPCQI
Sbjct: 2221 DGNVSSCGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWVPDHQPCQI 2280
Query: 2281 CTCLSGRKVNCTTQPCPTAKAPTCGLCEVARLRQNADQCCPEYECVCDPVSCDLPPVPHC 2340
CTCLSGRKVNCTTQPCPTAKAPTCGLCEVARLRQNADQCCPEYECVCDPVSCDLPPVPHC
Sbjct: 2281 CTCLSGRKVNCTTQPCPTAKAPTCGLCEVARLRQNADQCCPEYECVCDPVSCDLPPVPHC 2340
Query: 2341 ERGLQPTLTNPGECRPNFTCACRKEECKRVSPPSCPPHRLPTLRKTQCCDEYECACNCVN 2400
ERGLQPTLTNPGECRPNFTCACRKEECKRVSPPSCPPHRLPTLRKTQCCDEYECACNCVN
Sbjct: 2341 ERGLQPTLTNPGECRPNFTCACRKEECKRVSPPSCPPHRLPTLRKTQCCDEYECACNCVN 2400
Query: 2401 STVSCPLGYLASTATNDCGCTTTTCLPDKVCVHRSTIYPVGQFWEEGCDVCTCTDMEDAV 2460
STVSCPLGYLASTATNDCGCTTTTCLPDKVCVHRSTIYPVGQFWEEGCDVCTCTDMEDAV
Sbjct: 2401 STVSCPLGYLASTATNDCGCTTTTCLPDKVCVHRSTIYPVGQFWEEGCDVCTCTDMEDAV 2460
Query: 2461 MGLRVAQCSQKPCEDSCRSGFTYVLHEGECCGRCLPSACEVVTGSPRGDSQSSWKSVGSQ 2520
MGLRVAQCSQKPCEDSCRSGFTYVLHEGECCGRCLPSACEVVTGSPRGDSQSSWKSVGSQ
Sbjct: 2461 MGLRVAQCSQKPCEDSCRSGFTYVLHEGECCGRCLPSACEVVTGSPRGDSQSSWKSVGSQ 2520
Query: 2521 WASPENPCLINECVRVKEEVFIQQRNVSCPQLEVPVCPSGFQLSCKTSACCPSCRCERME 2580
WASPENPCLINECVRVKEEVFIQQRNVSCPQLEVPVCPSGFQLSCKTSACCPSCRCERME
Sbjct: 2521 WASPENPCLINECVRVKEEVFIQQRNVSCPQLEVPVCPSGFQLSCKTSACCPSCRCERME 2580
Query: 2581 ACMLNGTVIGPGKTVMIDVCTTCRCMVQVGVISGFKLECRKTTCNPCPLGYKEENNTGEC 2640
ACMLNGTVIGPGKTVMIDVCTTCRCMVQVGVISGFKLECRKTTCNPCPLGYKEENNTGEC
Sbjct: 2581 ACMLNGTVIGPGKTVMIDVCTTCRCMVQVGVISGFKLECRKTTCNPCPLGYKEENNTGEC 2640
Query: 2641 CGRCLPTACTIQLRGGQIMTLKRDETLQDGCDTHFCKVNERGEYFWEKRVTGCPPFDEHK 2700
CGRCLPTACTIQLRGGQIMTLKRDETLQDGCDTHFCKVNERGEYFWEKRVTGCPPFDEHK
Sbjct: 2641 CGRCLPTACTIQLRGGQIMTLKRDETLQDGCDTHFCKVNERGEYFWEKRVTGCPPFDEHK 2700
Query: 2701 CLAEGGKIMKIPGTCCDTCEEPECNDITARLQYVKVGSCKSEVEVDIHYCQGKCASKAMY 2760
CLAEGGKIMKIPGTCCDTCEEPECNDITARLQYVKVGSCKSEVEVDIHYCQGKCASKAMY
Sbjct: 2701 CLAEGGKIMKIPGTCCDTCEEPECNDITARLQYVKVGSCKSEVEVDIHYCQGKCASKAMY 2760
Query: 2761 SIDINDVQDQCSCCSPTRTEPMQVALHCTNGSVVYHEVLNAMECKCSPRKCSK 2813
SIDINDVQDQCSCCSPTRTEPMQVALHCTNGSVVYHEVLNAMECKCSPRKCSK
Sbjct: 2761 SIDINDVQDQCSCCSPTRTEPMQVALHCTNGSVVYHEVLNAMECKCSPRKCSK 2813
>gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]
Length = 5765
Score = 775 bits (2000), Expect = 0.0
Identities = 421/1236 (34%), Positives = 607/1236 (49%), Gaps = 83/1236 (6%)
Query: 35 CSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRSFSIIGDFQNGKRVSLSVYLGEFFDI 94
CS +G TFDG ++ F G C+Y+ + C+ + G S V
Sbjct: 77 CSTWGDFHYKTFDGDVFRFPGLCNYVFSEHCRAAYEDFNVQLRRGLVGSRPVVTRVVIKA 136
Query: 95 HLFV----NGTVTQGDQRVSMPYASKGLYLETEAGYYKLSGEAYGFVARIDGSGNFQVLL 150
V NG+V QR +PY+ GL +E Y K+S +G + + L
Sbjct: 137 QGLVLEASNGSVLINGQREELPYSRTGLLVEQSGDYIKVSIRLV-LTFLWNGEDSALLEL 195
Query: 151 SDRYFNKTCGLCGNFN-IFAEDDFMTQEGTLTSDPYDFANSWALSSGEQWCERASP-PSS 208
+Y N+TCGLCG+FN + A ++F LT P F N L + C P P+
Sbjct: 196 DPKYANQTCGLCGDFNGLPAFNEFYAHNARLT--PLQFGNLQKLDGPTEQCPDPLPLPAG 253
Query: 209 SCNISSGEMQKGLWEQCQLLKSTSVFARCHPLVDPEPFVALCEKTLCECAGGLECACPAL 268
+C G C FA CH LVD ++A C + LC C C C
Sbjct: 254 NCTDEEGI--------CHRTLLGPAFAECHALVDSTAYLAACAQDLCRCP---TCPCATF 302
Query: 269 LEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCARTCQSLHINEMCQERCVDG 328
+EY+R CA G W C CP M++++C SPC TC + ++C++ CVDG
Sbjct: 303 VEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTCSNPQRAQLCEDHCVDG 362
Query: 329 CSCPEGQ---LLDE---GLCVESTECPCVHSGKRYPPGTSLSRDCNTCICRNSQWICSNE 382
C CP G+ +LD+ C+ +CPC H G+ Y PGTS + C++C C W C +
Sbjct: 363 CFCPPGRSCTVLDDITHSGCLPLGQCPCTHGGRTYSPGTSFNTTCSSCTCSGGLWQCQDL 422
Query: 383 ECPGECLVTGQSHFKSFDNRYFTFSGICQYLLARDCQDHSFSIVIETVQCADDRDAVCTR 442
CPG C V G +H ++D + + G C Y+L++ C D SF+++ E +C + C +
Sbjct: 423 PCPGTCSVQGGAHISTYDEKLYDLHGDCSYVLSKKCADSSFTVLAELRKCGLTDNENCLK 482
Query: 443 SVTVRLPGLHNSLVKLKHGAGVAMDGQDVQLPLLKGDLRI--QHTVTASVRLSYGEDLQM 500
+VT+ L G ++ ++++ GV ++ QLPL ++ + + V+ G L +
Sbjct: 483 AVTLSLDG-GDTAIRVQADGGVFLNSIYTQLPLSAANITLFTPSSFFIVVQTGLGLQLLV 541
Query: 501 DWDGRGRLLVKLSPVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWKLHGDCQ 560
++ V+L P + G+ CGLCGN+N NQ DDF SG+ E F N WK C
Sbjct: 542 QLVPLMQVFVRLDPAHQGQMCGLCGNFNQNQADDFTALSGVVEATGAAFANTWKAQAACA 601
Query: 561 DLQKQHSDPCALNPRMTRFSEEACAVLTSPT--FEACHRAVSPLPYLRNCRYDVCSCSDG 618
+ + DPC+L+ ++ C+ LT P F CH ++P P+ NC +D C+C
Sbjct: 602 NARNSFEDPCSLSVENENYARHWCSRLTDPNSAFSRCHSIINPKPFHSNCMFDTCNCERS 661
Query: 619 RECLCGALASYAAACAGRGVRVA-WREPGRCEL---NCPKGQVYLQCGTPCNLTCRSLSY 674
+CLC AL+SY ACA +GV+++ WR+ G C NCPK Q Y C TCR LS
Sbjct: 662 EDCLCAALSSYVHACAAKGVQLSDWRD-GVCTKYMQNCPKSQRYAYVVDACQPTCRGLSE 720
Query: 675 PDEECNEACL--EGCFCPPGLYMDERGDCVPKAQCPCYYDGEIFQPEDIFSDHHTMCYCE 732
D C+ + + +GC CP G ++++ G CVP +CPCY G + P ++ D +C C
Sbjct: 721 ADVTCSVSFVPVDGCTCPAGTFLNDAGACVPAQECPCYAHGTVLAPGEVVHDEGAVCSCT 780
Query: 733 DGFMHCTMSGVPGSLLPDAVLSSPLSHRSKRSLSCRPPMVKLVCPADNLRAEGLECTKTC 792
G + C L ++S C PMV L C + G EC ++C
Sbjct: 781 GGKLSC------------------LGASLQKSTGCAAPMVYLDCSNSSAGTPGAECLRSC 822
Query: 793 QNYDLECMSMGCVSGCLCPPGMVRH-ENRCVALERCPCFHQGKEYAPGETVKIGCNTCVC 851
D+ C S CVSGC+CPPG+V C+A E CPC H Y PGET+++ CNTC C
Sbjct: 823 HTLDVGCFSTHCVSGCVCPPGLVSDGSGGCIAEEDCPCVHNEATYKPGETIRVDCNTCTC 882
Query: 852 RDRKWNCTDHVCDATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNP--GTFRILV 909
R+R+W C+ +C TC G H++TFDG +Y F G C+Y+L QDYCG N GTFRI+
Sbjct: 883 RNRRWECSHRLCLGTCVAYGDGHFITFDGDRYSFEGSCEYILAQDYCGDNTTHGTFRIVT 942
Query: 910 GNKGCSHPSVKCKKRVTILVEGGEIELFDGEVN-VKRPMKDETHFEVVESGRYIILLLGK 968
N C C K + + VE E+ L +G V R + +++ G ++++
Sbjct: 943 ENIPCGTTGTTCSKAIKLFVESYELILQEGTFKAVARGPGGDPPYKIRYMGIFLVIET-H 1001
Query: 969 ALSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKVS 1028
++V WDR S+ + L Q Y+ +VCGLCGNFD ND + + V D ++FGNSWK+S
Sbjct: 1002 GMAVSWDRKTSVFIRLHQDYKGRVCGLCGNFDDNAINDFATRSRSVVGDALEFGNSWKLS 1061
Query: 1029 SQCADTRKVPLDSSPATCHNNIMKQTMVDSSCRILTSDVFQDCNKLVDPEPYLDVCIYDT 1088
C D P D C N +++ C IL F C VD Y + C+ D
Sbjct: 1062 PSCPDA-LAPKD----PCTANPFRKSWAQKQCSILHGPTFAACRSQVDSTKYYEACVNDA 1116
Query: 1089 CSCESIGDCACFCDTIAAYAHVCAQHGKVVTWRTATLCPQSCEERNLRENGYECEWRYNS 1148
C+C+S GDC CFC +AAYA C G V+WRT CP C+ N CEW Y
Sbjct: 1117 CACDSGGDCECFCTAVAAYAQACHDAGLCVSWRTPDTCPLFCDFYNPHGG---CEWHYQP 1173
Query: 1149 CAPACQVTCQHPEPLACPVQC--VEGCHAHCPPGK-ILDELLQTCVDPEDCPVCEVAGRR 1205
C C TC++P C V +EGC+ CPP + +E CV C + G
Sbjct: 1174 CGAPCLKTCRNPSG-HCLVDLPGLEGCYPKCPPSQPFFNEDQMKCV--AQCGCYDKDGNY 1230
Query: 1206 FASGKKVTLNPSDPEHCQICHCDVVNLTC----EAC 1237
+ G +V E+CQ C+C + C EAC
Sbjct: 1231 YDVGARV----PTAENCQSCNCTPSGIQCAHSLEAC 1262
Score = 228 bits (581), Expect = 6e-59
Identities = 192/675 (28%), Positives = 279/675 (41%), Gaps = 88/675 (13%)
Query: 1887 KRPGDVWTLPDQCHTVTCQPDGQTLLKSHRVNCDRGLRPSCPNSQSPVKVEET---CGCR 1943
++ + WTL + C C D + +L + + +C N P+KV + C
Sbjct: 5017 RQVNETWTL-ENCTVARCVGDNRVVLLDPKPVAN----VTCVNKHLPIKVSDPSQPCDFH 5071
Query: 1944 WTCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQN---KEQDLEVILHNGACSPGARQG 2000
+ C C+C+ H TFDG ++ G+C+YVL + + +L + L N C+ A
Sbjct: 5072 YECECICSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYLDNHYCTASATAA 5131
Query: 2001 ---CMKSIEVKHSALSVELHSDMEVTVNGRLV---SVPYVGG----NMEVNVYGAIMHEV 2050
C +++ + + ++ + L M L+ +P G + V+V G V
Sbjct: 5132 AARCPRALSIHYKSMDIVLTVTMVHGKEEGLILFDQIPVSSGFSKNGVLVSVLGTTTMRV 5191
Query: 2051 RFNHLGHIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTL 2110
LG TF Q FQ +L F + T G CG C N +D + RDGT K +
Sbjct: 5192 DIPALGVSVTFNGQ--VFQARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTAASCKDM 5249
Query: 2111 VQEWTV---QRPG--------QTCQPILEEQCL-----VPDSSHCQVLLLPLFAECHKVL 2154
+ W V ++ G T P P C ++L +FAECH ++
Sbjct: 5250 AKTWLVPDSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQPLCDLMLSQVFAECHNLV 5309
Query: 2155 APATFYAICQQDSC--HQEQVCEVIASYAHLCRTNGVCVDWR--TPDFCAMSCPPSLVYN 2210
P F+ C D C E C+ + +YA LCR GVC DWR T C ++CPP+ VY
Sbjct: 5310 PPGPFFNACISDHCRGRLEVPCQSLEAYAELCRARGVCSDWRGATGGLCDLTCPPTKVYK 5369
Query: 2211 HCEHGCPRHCDG-NVSSCGDHPSEGCFCPPDKVMLE---GSCVPEEACTQCIGEDGVQHQ 2266
C P C+ N S + +EGCFCP D+++ G CV +AC C+G DG
Sbjct: 5370 PCGPIQPATCNSRNQSPQLEGMAEGCFCPEDQILFNAHMGICV--QAC-PCVGPDGFPKF 5426
Query: 2267 FLEAWVPDHQPCQICTCLSGR-KVNCTTQPCPT-AKAPTC---GLCEVARLRQNADQCCP 2321
E WV + CQ C C G V C PC + P C G V R R + CCP
Sbjct: 5427 PGERWVSN---CQSCVCDEGSVSVQCKPLPCDAQGQPPPCNRPGFVTVTRPRAE-NPCCP 5482
Query: 2322 EYECVCDPVSCDLPPVPHCERGLQPTLT-NPGECRPNFTCACRKEECK---------RVS 2371
E CVC+ +C +P C G + T G+C P F CR + C
Sbjct: 5483 ETVCVCNTTTCP-QSLPVCPPGQESICTQEEGDCCPTF--RCRPQLCSYNGTFYGVGATF 5539
Query: 2372 PPSCPPHRLPTLRKTQCCDEYECACNCVNSTVSCPLGYLASTATNDC--GCTTTTCL-PD 2428
P + P H L +C + N+T +CP G+ C C T CL PD
Sbjct: 5540 PGALPCHMCTCLSGDTQDPTVQCQEDACNNT-TCPQGFEYKRVAGQCCGECVQTACLTPD 5598
Query: 2429 KVCVHRSTIYPVGQFWEEGCDVCTCTDMEDAVMGLRVAQCSQKPCED--SCRSGFTYVLH 2486
V + + + C V C +A G+ + C D SCR L
Sbjct: 5599 GQPVQLNETWVNSHV--DNCTVYLC----EAEGGVHLLTPQPASCPDVSSCRGS----LR 5648
Query: 2487 EGECCGRCLPSACEV 2501
+ CC C +C+V
Sbjct: 5649 KTGCCYSCEEDSCQV 5663
Score = 148 bits (373), Expect = 8e-35
Identities = 121/415 (29%), Positives = 171/415 (41%), Gaps = 53/415 (12%)
Query: 2419 GCTTTTCLPDKVCVHRSTIYPVG----------QFWEEGCDVCTCTDMEDAVMGLRVAQC 2468
G TC P KV I P + EGC + +A MG+ V C
Sbjct: 5356 GLCDLTCPPTKVYKPCGPIQPATCNSRNQSPQLEGMAEGCFCPEDQILFNAHMGICVQAC 5415
Query: 2469 S--------QKPCEDSCRSGFTYVLHEGECCGRCLPSACEVVTGSPRGDSQSSWKSVGSQ 2520
+ P E + + V EG +C P C+ G P ++ + +V
Sbjct: 5416 PCVGPDGFPKFPGERWVSNCQSCVCDEGSVSVQCKPLPCDA-QGQPPPCNRPGFVTVTRP 5474
Query: 2521 WASPENPCLINECVRVKEEVFIQQRNVSCPQLEVPVCPSGFQLSC--KTSACCPSCRCER 2578
A ENPC E +CPQ +PVCP G + C + CCP+ RC R
Sbjct: 5475 RA--ENPCC--------PETVCVCNTTTCPQ-SLPVCPPGQESICTQEEGDCCPTFRC-R 5522
Query: 2579 MEACMLNGTVIGPGKTVMIDV-CTTCRCMVQVGVISGFKLECRKTTCN--PCPLGYKEEN 2635
+ C NGT G G T + C C C+ G ++C++ CN CP G++ +
Sbjct: 5523 PQLCSYNGTFYGVGATFPGALPCHMCTCLS--GDTQDPTVQCQEDACNNTTCPQGFEYKR 5580
Query: 2636 NTGECCGRCLPTACTIQLRGGQIMTLKRD--ETLQDGCDTHFCKVNERGEYFWEKRVTGC 2693
G+CCG C+ TAC GQ + L + D C + C+ E G + + C
Sbjct: 5581 VAGQCCGECVQTACLTP--DGQPVQLNETWVNSHVDNCTVYLCEA-EGGVHLLTPQPASC 5637
Query: 2694 PPFDEHKCLAEGGKIMKIPGTCCDTCEEPECNDITARLQYVKVGSCKSEVEVDIHYCQGK 2753
P D C G + K CC +CEE C R+ + E EV+I +C+G
Sbjct: 5638 P--DVSSCR---GSLRKTG--CCYSCEEDSCQ---VRINTTILWHQGCETEVNITFCEGS 5687
Query: 2754 CASKAMYSIDINDVQDQCSCCSPTRTEPMQVALHCTNGSVVYHEVLNAMECKCSP 2808
C + YS + +Q QC+CC R V LHC NGS + H + EC C+P
Sbjct: 5688 CPGASKYSAEAQAMQHQCTCCQERRVHEETVPLHCPNGSAILHTYTHVDECGCTP 5742
Score = 132 bits (331), Expect = 6e-30
Identities = 163/665 (24%), Positives = 243/665 (36%), Gaps = 85/665 (12%)
Query: 263 CACPALLEYARTCAQEGMVLYGWTDHSACS--PVCPAGMEYRQCVSPCARTCQSLHINEM 320
C C A ++ G V+Y TD + C VC + + C + + +
Sbjct: 4946 CFCRAFGQFF----SPGEVIYNKTDRAGCHFYAVCNQHCDIDRFQGACPTSPPPVSSAPL 5001
Query: 321 CQERCVDGC--SCPEGQLLDEGLCVESTECPCVHSG-------KRYPPGTSLSRDCNTCI 371
GC + P Q+ + T CV K T +++ +
Sbjct: 5002 SSPSPAPGCDNAIPLRQVNETWTLENCTVARCVGDNRVVLLDPKPVANVTCVNKHLPIKV 5061
Query: 372 CRNSQWICSNEECPGECLVTGQSHFKSFDNRYFTFSGICQYLLARDCQDH--SFSIVIET 429
SQ + EC C + G SH+ +FD +TF G C Y+L R+ + S+ ++
Sbjct: 5062 SDPSQPCDFHYECECICSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYLDN 5121
Query: 430 VQCADDRDAV---CTRSVTVRLPGLHNSL-VKLKHGAG---VAMDGQDVQLPLLKGDLRI 482
C A C R++++ + L V + HG + D V K + +
Sbjct: 5122 HYCTASATAAAARCPRALSIHYKSMDIVLTVTMVHGKEEGLILFDQIPVSSGFSKNGVLV 5181
Query: 483 QHTVTASVRLSYGEDLQMDWDGRGRLLVKLSP--VYAGKTCGLCGNYNGNQGDDFLTPSG 540
T ++R+ L + G++ P ++ T G CG NQ DD L G
Sbjct: 5182 SVLGTTTMRVDI-PALGVSVTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDG 5240
Query: 541 LAEPRVEDFGNAWKLHGDCQD---------LQKQHSDPCALNPRMTRF-SEEACAVLTSP 590
+D W + +D + P + P T + C ++ S
Sbjct: 5241 TTAASCKDMAKTWLVPDSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQPLCDLMLSQ 5300
Query: 591 TFEACHRAVSPLPYLRNCRYDVCSCSDGR-ECLCGALASYAAACAGRGVRVAWR--EPGR 647
F CH V P P+ C D C GR E C +L +YA C RGV WR G
Sbjct: 5301 VFAECHNLVPPGPFFNACISDHCR---GRLEVPCQSLEAYAELCRARGVCSDWRGATGGL 5357
Query: 648 CELNCPKGQVYLQCGTPCNLTCRSLSYPDEECNEACLEGCFCPPG--LYMDERGDCVPKA 705
C+L CP +VY CG TC S + + E EGCFCP L+ G CV
Sbjct: 5358 CDLTCPPTKVYKPCGPIQPATCNSRNQSPQ--LEGMAEGCFCPEDQILFNAHMGICV--Q 5413
Query: 706 QCPCY-YDGEIFQPEDIFSDHHTMCYCEDGFMHCTMSGVPGSLLPDAVLSSPLSHRSKRS 764
CPC DG P + + + C C++G + +P DA P +
Sbjct: 5414 ACPCVGPDGFPKFPGERWVSNCQSCVCDEGSVSVQCKPLP----CDAQGQPPPCN----- 5464
Query: 765 LSCRPPMVKLVCPADNLRAEGLECTKTCQNYDLECMSMGCVSGC-LCPPGM----VRHEN 819
RP V + P RAE C +T C + C +CPPG + E
Sbjct: 5465 ---RPGFVTVTRP----RAENPCCPETV----CVCNTTTCPQSLPVCPPGQESICTQEEG 5513
Query: 820 RCVALERCP---CFHQGKEYAPGETV--KIGCNTCVC-----RDRKWNCTDHVCDATCST 869
C RC C + G Y G T + C+ C C +D C + C+ T
Sbjct: 5514 DCCPTFRCRPQLCSYNGTFYGVGATFPGALPCHMCTCLSGDTQDPTVQCQEDACNNTTCP 5573
Query: 870 IGMAH 874
G +
Sbjct: 5574 QGFEY 5578
Score = 113 bits (283), Expect = 2e-24
Identities = 102/366 (27%), Positives = 152/366 (41%), Gaps = 33/366 (9%)
Query: 1949 VCTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKE---QDLEVILHNGACSPGARQGCMKSI 2005
VC+ H TFDG F+ G C+YV ++ +D V L G G+R + +
Sbjct: 76 VCSTWGDFHYKTFDGDVFRFPGLCNYVFSEHCRAAYEDFNVQLRRGLV--GSRP-VVTRV 132
Query: 2006 EVKHSALSVELHSDMEVTVNGRLVSVPYVGGNMEVNVYGA-IMHEVRFNHLGHIFTFTPQ 2064
+K L +E S+ V +NG+ +PY + V G I +R + TF
Sbjct: 133 VIKAQGLVLEA-SNGSVLINGQREELPYSRTGLLVEQSGDYIKVSIRL-----VLTFLWN 186
Query: 2065 NNEFQL-QLSPKTFASKTYGLCGICDENGA---NDFMLRDGTVTTDWKTLVQEWTVQRPG 2120
+ L +L PK +A++T GLCG D NG N+F + +T +Q+ + P
Sbjct: 187 GEDSALLELDPK-YANQTCGLCG--DFNGLPAFNEFYAHNARLTPLQFGNLQK--LDGPT 241
Query: 2121 QTCQ---PILEEQCLVPDSSHCQVLLLPLFAECHKVLAPATFYAICQQDSCHQEQV-CEV 2176
+ C P+ C + + LL P FAECH ++ + A C QD C C
Sbjct: 242 EQCPDPLPLPAGNCTDEEGICHRTLLGPAFAECHALVDSTAYLAACAQDLCRCPTCPCAT 301
Query: 2177 IASYAHLC-RTNGVCVDWRTPDFCAMSCPPSLVYNHCEHGCPRHCDG--NVSSCGDHPSE 2233
Y+ C G +WR P+ C +CP ++ + C C C C DH +
Sbjct: 302 FVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTCSNPQRAQLCEDHCVD 361
Query: 2234 GCFCPPDKVMLEGSCVPEEACTQCIGEDGVQH--QFLEAWVPDHQPCQICTCLSGRKVNC 2291
GCFCPP + + C +G+ H + + C CTC SG C
Sbjct: 362 GCFCPPGRSCTVLDDITHSGCLP-LGQCPCTHGGRTYSPGTSFNTTCSSCTC-SGGLWQC 419
Query: 2292 TTQPCP 2297
PCP
Sbjct: 420 QDLPCP 425
Score = 113 bits (282), Expect = 3e-24
Identities = 100/370 (27%), Positives = 148/370 (40%), Gaps = 39/370 (10%)
Query: 35 CSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKR----SFSIIGDFQNGKRVSLSVYLGE 90
CS++G +TFDG+ Y+F G C+Y+L R S + + + +
Sbjct: 5078 CSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYLDNHYCTASATAAAARCPR 5137
Query: 91 FFDIH-----LFVNGTVTQGDQR---------VSMPYASKGLYLET-EAGYYKLSGEAYG 135
IH + + T+ G + VS ++ G+ + ++ A G
Sbjct: 5138 ALSIHYKSMDIVLTVTMVHGKEEGLILFDQIPVSSGFSKNGVLVSVLGTTTMRVDIPALG 5197
Query: 136 FVARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSS 195
+G L + N T G CG DD + ++GT + D A +W +
Sbjct: 5198 VSVTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTAASCKDMAKTWLVPD 5257
Query: 196 GEQ---WCERASPPSSS--CNISSGEMQKGLWEQ--CQLLKSTSVFARCHPLVDPEPFVA 248
+ W +PP++S +SS Q C L+ S VFA CH LV P PF
Sbjct: 5258 SRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQPLCDLMLS-QVFAECHNLVPPGPFFN 5316
Query: 249 LCEKTLCECAGGLECACPALLEYARTCAQEGMVLYGWTDHSA--CSPVCPAGMEYRQCVS 306
C C G LE C +L YA C G V W + C CP Y+ C
Sbjct: 5317 ACISD--HCRGRLEVPCQSLEAYAELCRARG-VCSDWRGATGGLCDLTCPPTKVYKPCGP 5373
Query: 307 PCARTCQSLHINEMCQERCVDGCSCPEGQLL---DEGLCVESTECPCV-HSGKRYPPGTS 362
TC S + + E +GC CPE Q+L G+CV++ CPCV G PG
Sbjct: 5374 IQPATCNSRNQSPQL-EGMAEGCFCPEDQILFNAHMGICVQA--CPCVGPDGFPKFPGER 5430
Query: 363 LSRDCNTCIC 372
+C +C+C
Sbjct: 5431 WVSNCQSCVC 5440
Score = 112 bits (281), Expect = 4e-24
Identities = 132/530 (24%), Positives = 199/530 (37%), Gaps = 58/530 (10%)
Query: 1877 RICMDE--DGNEKRPGDVWTLPDQCHTVTCQPDGQTLLKSHRVNCDRGLRPSCPNSQSPV 1934
++C D DG PG T+ D C P GQ C G R P +
Sbjct: 353 QLCEDHCVDGCFCPPGRSCTVLDDITHSGCLPLGQC-------PCTHGGRTYSPGTSFNT 405
Query: 1935 KVEE-TC-GCRWTC---PC--VCTGSSTRHIVTFDGQNFKLTGSCSYVLFQN-KEQDLEV 1986
TC G W C PC C+ HI T+D + + L G CSYVL + + V
Sbjct: 406 TCSSCTCSGGLWQCQDLPCPGTCSVQGGAHISTYDEKLYDLHGDCSYVLSKKCADSSFTV 465
Query: 1987 ILHNGACSPGARQGCMKSIEVKHSA--LSVELHSDMEVTVNGRLVSVPYVGGNMEVNVYG 2044
+ C + C+K++ + ++ + +D V +N +P N+ +
Sbjct: 466 LAELRKCGLTDNENCLKAVTLSLDGGDTAIRVQADGGVFLNSIYTQLPLSAANITLFTPS 525
Query: 2045 AIMHEVRFN-HLGHIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTV 2103
+ V+ L + P F ++L P + GLCG ++N A+DF G V
Sbjct: 526 SFFIVVQTGLGLQLLVQLVPLMQVF-VRLDP-AHQGQMCGLCGNFNQNQADDFTALSGVV 583
Query: 2104 TTDWKTLVQEWTVQRPGQTCQPILEEQCLVPDSSH------CQVLLLP--LFAECHKVLA 2155
W Q + E+ C + + C L P F+ CH ++
Sbjct: 584 EATGAAFANTWKAQAACANARNSFEDPCSLSVENENYARHWCSRLTDPNSAFSRCHSIIN 643
Query: 2156 PATFYAICQQDSCHQEQ----VCEVIASYAHLCRTNGVCV-DWRTPDFCA---MSCPPSL 2207
P F++ C D+C+ E+ +C ++SY H C GV + DWR C +CP S
Sbjct: 644 PKPFHSNCMFDTCNCERSEDCLCAALSSYVHACAAKGVQLSDWR-DGVCTKYMQNCPKSQ 702
Query: 2208 VYNHCEHGCPRHCDG-----NVSSCGDHPSEGCFCPPDKVMLE-GSCVPEEACTQCIGED 2261
Y + C C G S P +GC CP + + G+CVP + C C
Sbjct: 703 RYAYVVDACQPTCRGLSEADVTCSVSFVPVDGCTCPAGTFLNDAGACVPAQEC-PCYAHG 761
Query: 2262 GVQHQFLEAWVPDHQPCQICTCLSGRKVNCTTQPCPTAKAPTCGLCEVARLRQNADQCCP 2321
V L H +C+C +G K++C K+ C V N+ P
Sbjct: 762 TV----LAPGEVVHDEGAVCSC-TGGKLSCL--GASLQKSTGCAAPMVYLDCSNSSAGTP 814
Query: 2322 EYECVCDPVSCDLPPV-PHCERG--LQPTLTNPGE--CRPNFTCACRKEE 2366
EC+ + D+ HC G P L + G C C C E
Sbjct: 815 GAECLRSCHTLDVGCFSTHCVSGCVCPPGLVSDGSGGCIAEEDCPCVHNE 864
Score = 108 bits (270), Expect = 7e-23
Identities = 99/389 (25%), Positives = 144/389 (37%), Gaps = 63/389 (16%)
Query: 1939 TCGCR---WTCP---CV--CTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKEQD------L 1984
TC CR W C C+ C H +TFDG + GSC Y+L Q+ D
Sbjct: 879 TCTCRNRRWECSHRLCLGTCVAYGDGHFITFDGDRYSFEGSCEYILAQDYCGDNTTHGTF 938
Query: 1985 EVILHNGACSPGARQGCMKSIEVKHSALSVELHSDMEVTV-----NGRLVSVPYVGGNME 2039
++ N C C K+I++ + + L V + Y+G +
Sbjct: 939 RIVTENIPCGTTGTT-CSKAIKLFVESYELILQEGTFKAVARGPGGDPPYKIRYMGIFLV 997
Query: 2040 VNVYGAIMHEVRFNHLGHIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLR 2099
+ +G V ++ +F Q+ + + GLCG D+N NDF R
Sbjct: 998 IETHGMA---VSWDRKTSVFIRLHQD-----------YKGRVCGLCGNFDDNAINDFATR 1043
Query: 2100 DGTVTTDWKTLVQEWTVQRPGQTCQPIL--EEQCLVPD------SSHCQVLLLPLFAECH 2151
+V D W + +C L ++ C C +L P FA C
Sbjct: 1044 SRSVVGDALEFGNSWKLS---PSCPDALAPKDPCTANPFRKSWAQKQCSILHGPTFAACR 1100
Query: 2152 KVLAPATFYAICQQDSC------HQEQVCEVIASYAHLCRTNGVCVDWRTPDFCAMSCP- 2204
+ +Y C D+C E C +A+YA C G+CV WRTPD C + C
Sbjct: 1101 SQVDSTKYYEACVNDACACDSGGDCECFCTAVAAYAQACHDAGLCVSWRTPDTCPLFCDF 1160
Query: 2205 ------PSLVYNHCEHGCPRHCDGNVSSC-GDHPS-EGCF--CPPDKVMLEGSCVPEEAC 2254
Y C C + C C D P EGC+ CPP + + A
Sbjct: 1161 YNPHGGCEWHYQPCGAPCLKTCRNPSGHCLVDLPGLEGCYPKCPPSQPFFNEDQMKCVAQ 1220
Query: 2255 TQCIGEDGVQHQFLEAWVPDHQPCQICTC 2283
C +DG + + A VP + CQ C C
Sbjct: 1221 CGCYDKDG-NYYDVGARVPTAENCQSCNC 1248
Score = 102 bits (255), Expect = 4e-21
Identities = 112/439 (25%), Positives = 164/439 (37%), Gaps = 67/439 (15%)
Query: 863 CDATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPGTFRILVGNKGC----SHPS 918
C+ CS G +HY TFDG Y F G C YVL+++ + G + + N C + +
Sbjct: 5074 CECICSMWGGSHYSTFDGTSYTFRGNCTYVLMRE-IHARFGNLSLYLDNHYCTASATAAA 5132
Query: 919 VKCKKRVTILVEGGEIELFDGEVNVKRPMKDETHFEVVESG----RYIILLLGKALSVVW 974
+C + ++I + +I L V+ K V SG ++ +LG V
Sbjct: 5133 ARCPRALSIHYKSMDIVLTVTMVHGKEEGLILFDQIPVSSGFSKNGVLVSVLGTTTMRVD 5192
Query: 975 DRHLSISVVLK-QTYQEKVC---------GLCGNFDGIQNNDLTSSNLQVEEDPVDFGNS 1024
L +SV Q +Q ++ G CG Q +D + D +
Sbjct: 5193 IPALGVSVTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTAASCKDMAKT 5252
Query: 1025 WKVSSQCADTRKVPLDSSPATCHNNIMKQTMVDSS------CRILTSDVFQDCNKLVDPE 1078
W V D P + P + T + C ++ S VF +C+ LV P
Sbjct: 5253 WLVPDSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQPLCDLMLSQVFAECHNLVPPG 5312
Query: 1079 PYLDVCIYDTCSCESIGDCACFCDTIAAYAHVCAQHGKVVTWRTAT--LCPQSCEERNLR 1136
P+ + CI D C G C ++ AYA +C G WR AT LC +C +
Sbjct: 5313 PFFNACISDHCR----GRLEVPCQSLEAYAELCRARGVCSDWRGATGGLCDLTCPPTKV- 5367
Query: 1137 ENGYECEWRYNSCAPACQVTCQHPEPLACPVQCVEGCHAHCPPGKIL-DELLQTCVDPED 1195
Y C P TC EGC CP +IL + + CV +
Sbjct: 5368 ---------YKPCGPIQPATCNSRNQSPQLEGMAEGC--FCPEDQILFNAHMGICV--QA 5414
Query: 1196 CPVCEVAGRRFASGKKVTLNPSDPEHCQICHCDVVN-------LTCEA------CQEPGG 1242
CP G G++ N CQ C CD + L C+A C PG
Sbjct: 5415 CPCVGPDGFPKFPGERWVSN------CQSCVCDEGSVSVQCKPLPCDAQGQPPPCNRPGF 5468
Query: 1243 LVV--PPTDAPVSPTTLYV 1259
+ V P + P P T+ V
Sbjct: 5469 VTVTRPRAENPCCPETVCV 5487
Score = 42.0 bits (97), Expect = 0.009
Identities = 56/230 (24%), Positives = 84/230 (36%), Gaps = 57/230 (24%)
Query: 2542 IQQRNVSCPQLEVPV----CPSGFQLSCKTSACCPSCRCERMEACMLNGTVIGPGKTVMI 2597
+ + +V+C VPV CP+G L+ AC P+ C C +GTV+ PG+ V+
Sbjct: 718 LSEADVTCSVSFVPVDGCTCPAGTFLN-DAGACVPAQECP----CYAHGTVLAPGE-VVH 771
Query: 2598 DVCTTCRCMVQVGVISGFKLEC-----RKTTCNPCPLGYKEENNT------GECCGRC-- 2644
D C C +G KL C +K+T P+ Y + +N+ EC C
Sbjct: 772 DEGAVCSC-------TGGKLSCLGASLQKSTGCAAPMVYLDCSNSSAGTPGAECLRSCHT 824
Query: 2645 ---------------LPTACTIQLRGGQI-----------MTLKRDETLQDGCDTHFCKV 2678
P GG I T K ET++ C+T C+
Sbjct: 825 LDVGCFSTHCVSGCVCPPGLVSDGSGGCIAEEDCPCVHNEATYKPGETIRVDCNTCTCR- 883
Query: 2679 NERGEYFWEKRVTGCPPFDEHKCLAEGGKIMKIPGTCCDTCEEPECNDIT 2728
N R E + C + + + G G+C + C D T
Sbjct: 884 NRRWECSHRLCLGTCVAYGDGHFITFDGDRYSFEGSCEYILAQDYCGDNT 933
Score = 36.2 bits (82), Expect = 0.47
Identities = 32/124 (25%), Positives = 45/124 (36%), Gaps = 21/124 (16%)
Query: 2363 RKEECKRVSPPSCPPHRLPTLRKTQCCDEYE-------CACNCVNSTVSCPLGYLASTAT 2415
R C + P +CP + + C D C +CV+ CP G + T
Sbjct: 317 RNWRCPELCPRTCPLNMQHQECGSPCTDTCSNPQRAQLCEDHCVDGCF-CPPGR-SCTVL 374
Query: 2416 NDCGCTTTTCLP--DKVCVHRSTIYPVGQFWEEGCDVCTCTDMEDAVMGLRVAQCSQKPC 2473
+D T + CLP C H Y G + C CTC+ + QC PC
Sbjct: 375 DDI--THSGCLPLGQCPCTHGGRTYSPGTSFNTTCSSCTCSG--------GLWQCQDLPC 424
Query: 2474 EDSC 2477
+C
Sbjct: 425 PGTC 428
Score = 33.5 bits (75), Expect = 3.0
Identities = 23/81 (28%), Positives = 34/81 (41%), Gaps = 15/81 (18%)
Query: 1879 CMDEDGNEKRPGDVWTLPDQCHTVTCQPDGQTLLKSHRVNCD-RGLRPSC---------- 1927
C+ DG K PG+ W C + C +G ++ + CD +G P C
Sbjct: 5417 CVGPDGFPKFPGERWV--SNCQSCVCD-EGSVSVQCKPLPCDAQGQPPPCNRPGFVTVTR 5473
Query: 1928 PNSQSPVKVEETCGCR-WTCP 1947
P +++P E C C TCP
Sbjct: 5474 PRAENPCCPETVCVCNTTTCP 5494
Score = 32.0 bits (71), Expect = 8.8
Identities = 38/138 (27%), Positives = 53/138 (38%), Gaps = 18/138 (13%)
Query: 2543 QQRNVSCPQLEVPVCPSGFQLSCKTSACCPSC----RCERMEACMLNGTVIGPGK--TVM 2596
Q RN CP+L CP Q S C +C R + E ++G PG+ TV+
Sbjct: 315 QPRNWRCPELCPRTCPLNMQHQECGSPCTDTCSNPQRAQLCEDHCVDGCFCPPGRSCTVL 374
Query: 2597 IDVC-TTCRCMVQVGVISGFKL----ECRKTTCNPCPLGYKEENNTGECCGRCLPTACTI 2651
D+ + C + Q G + TTC+ C +C P C++
Sbjct: 375 DDITHSGCLPLGQCPCTHGGRTYSPGTSFNTTCSSCTC----SGGLWQCQDLPCPGTCSV 430
Query: 2652 QLRGGQIMTLKRDETLQD 2669
Q G I T DE L D
Sbjct: 431 Q-GGAHISTY--DEKLYD 445
>gi|169202626 PREDICTED: similar to mucin 5, partial [Homo sapiens]
Length = 2013
Score = 763 bits (1971), Expect = 0.0
Identities = 425/1258 (33%), Positives = 614/1258 (48%), Gaps = 86/1258 (6%)
Query: 35 CSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQK--RSFSI-IGDFQNGKRVSLSVYLGEF 91
CS +GS TFDG ++ F G C+Y+ + C F+I + Q +LS L +
Sbjct: 81 CSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRSQESAAPTLSRVLMKV 140
Query: 92 FDIHL-FVNGTVTQGDQRVSMPYASKGLYLETEAGYYKLSGEAYGFVARIDGSGNFQVLL 150
+ + G+V V +P++ G+ ++ + Y K+ G V + + + L
Sbjct: 141 DGVVIQLTKGSVLVNGHPVLLPFSQSGVLIQQSSSYTKVEARL-GLVLMWNHDDSLLLEL 199
Query: 151 SDRYFNKTCGLCGNFN-IFAEDDFMTQEGTLTSDPYDFANSWALSSGEQWCERASP-PSS 208
+Y NKTCGLCG+FN + + ++ LT P +F N + + C+ P P
Sbjct: 200 DTKYANKTCGLCGDFNGMPVVSELLSHNTKLT--PMEFGNLQKMDDPTEQCQDPVPEPPR 257
Query: 209 SCNISSGEMQKGLWEQCQLLKSTSVFARCHPLVDPEPFVALCEKTLCECAGG--LECACP 266
+C+ G C+ L +F+ C LVD ++ C + LC C L C C
Sbjct: 258 NCSTGFGI--------CEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDLLSCVCH 309
Query: 267 ALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCARTCQSLHINEMCQERCV 326
L EY+R C G + W C CP M+Y +C SPCA TC + + C++ CV
Sbjct: 310 TLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCSNQEHSRACEDHCV 369
Query: 327 DGCSCPEGQLLDE---GLCVESTECPCVHSGKRYPPGTSLSRDCNTCICRNSQWICSNEE 383
GC CPEG +LD+ CV ++C CV++G Y PG + S DC C C +W C
Sbjct: 370 AGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATYSTDCTNCTCSGGRWSCQEVP 429
Query: 384 CPGECLVTGQSHFKSFDNRYFTFSGICQYLLARDCQDHSFSIVIETVQCADDRDAVCTRS 443
CPG C V G +HF +FD + +T G C Y+L + C +F+++ E +C C +S
Sbjct: 430 CPGTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSAFTVLAELRRCGLTDSETCLKS 489
Query: 444 VTVRLPGLHNSLVKLKHGAGVAMDGQDVQLPLLKGDLRIQHTVTASV--RLSYGEDLQMD 501
VT+ L G+ ++V +K V ++ QLP+ ++ I T + + S G L +
Sbjct: 490 VTLSLDGVQ-TVVVIKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQ 548
Query: 502 WDGRGRLLVKLSPVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWKLHGDCQD 561
+L ++L+P G+TCGLCGN+N Q DDF T SG+ E F N +K C +
Sbjct: 549 LVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTFKTQAACPN 608
Query: 562 LQKQHSDPCALNPRMTRFSEEACAVLTSPT--FEACHRAVSPLPYLRNCRYDVCSCSDGR 619
++ DPC+L+ ++++ C+ LT F CH AV P Y NC +D C+C
Sbjct: 609 IRNSFEDPCSLSVENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCMFDTCNCERSE 668
Query: 620 ECLCGALASYAAACAGRGVRVAWREPGRCE---LNCPKGQVYLQCGTPCNLTCRSLSYPD 676
+CLC AL+SY ACA +GV++ G C CPK Y + C TCRSLS D
Sbjct: 669 DCLCAALSSYVHACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHYHVSTCQPTCRSLSEGD 728
Query: 677 EECNEACL--EGCFCPPGLYMDERGDCVPKAQCPCYYDGEIFQPEDIFSDHHTMCYCEDG 734
C+ + +GC CP G ++D+ G CV + CPCY+ G + + D +C C G
Sbjct: 729 ITCSVGFIPVDGCICPKGTFLDDTGKCVQASNCPCYHRGSMIPNGESVHDSGAICTCTHG 788
Query: 735 FMHCTMSGVPGSLLPDAVLSSPLSHRSKRSLSCRPPMVKLVCPADNLRAEGLECTKTCQN 794
+ C P + C PMV C G C K+C
Sbjct: 789 KLSCIGGQAPAPV-------------------CAAPMVFFDCRNATPGDTGAGCQKSCHT 829
Query: 795 YDLECMSMGCVSGCLCPPGMVRH-ENRCVALERCPCFHQGKEYAPGETVKIGCNTCVCRD 853
D+ C S CV GC+CP G+V E C+ E CPC H Y G+T+++GCNTC C
Sbjct: 830 LDMTCYSPQCVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTIRVGCNTCTCDS 889
Query: 854 RKWNCTDHVCDATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPGT---FRILVG 910
R W CTD C ATC+ G HYLTFDG Y F G+C+Y LVQ++CG T FR++
Sbjct: 890 RMWRCTDDPCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVVTE 949
Query: 911 NKGCSHPSVKCKKRVTILVEGGEIELFDGEVNV-KRPMKDETHFEVVESGRYIILLLGKA 969
N C C K + I + G E++L G+V V E + + + G Y+++
Sbjct: 950 NVPCGTTGTTCSKAIKIFLGGFELKLSHGKVEVIGTDESQEVPYTIRQMGIYLVVDTDIG 1009
Query: 970 LSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKVSS 1029
L ++WD+ SI + L ++ +VCGLCGNFD I ND + + V D ++FGNSWK+S
Sbjct: 1010 LVLLWDKKTSIFINLSPEFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSWKLSP 1069
Query: 1030 QCADTRKVPLDSSPATCHNNIMKQTMVDSSCRILTSDVFQDCNKLVDPEPYLDVCIYDTC 1089
C D P D C N +++ C IL F C+ V+P Y + C+ D C
Sbjct: 1070 SCPDA-LAPKD----PCTANPFRKSWAQKQCSILHGPTFAACHAHVEPARYYEACVNDAC 1124
Query: 1090 SCESIGDCACFCDTIAAYAHVCAQHGKVVTWRTATLCPQSCEERNLRENGYECEWRYNSC 1149
+C+S GDC CFC +AAYA C + G V+WRT ++CP C+ N +CEW Y C
Sbjct: 1125 ACDSGGDCECFCTAVAAYAQACHEVGLCVSWRTPSICPLFCDYYNPEG---QCEWHYQPC 1181
Query: 1150 APACQVTCQHPE-PLACPVQCVEGCHAHCPP-GKILDE----LLQTCVDPEDCPVCEVAG 1203
C TC++P V +EGC+ CPP I DE + TC P P C V G
Sbjct: 1182 GVPCLRTCRNPRGDCLRDVWGLEGCYPKCPPEAPIFDEDKMQCVATCPTPPLPPRCHVHG 1241
Query: 1204 RRFASGKKVTLNPSDPEHCQICHCDVVNLTC----EACQ--------EPGGLVVPPTD 1249
+ + G V PSD ++CQ C C + C EAC PG ++ TD
Sbjct: 1242 KSYRPGAVV---PSD-KNCQSCLCTERGVECTYKAEACVCTYNGQRFHPGDVIYHTTD 1295
Score = 141 bits (356), Expect = 8e-33
Identities = 120/418 (28%), Positives = 174/418 (41%), Gaps = 48/418 (11%)
Query: 33 ARCSLFGSDFVNTFDGSMYSFAGYCSYLL----AGG--CQKRSFSII------GDFQNGK 80
A C+++G TFDG YSF G C Y L GG + SF ++ G
Sbjct: 901 ATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPCGTTGTTC 960
Query: 81 RVSLSVYLGEFFDIHLFVNGTVTQG-DQRVSMPYASKGLYLETEAGYYKLSGEAYGFVAR 139
++ ++LG F++ L G D+ +PY + + G Y + G V
Sbjct: 961 SKAIKIFLGG-FELKLSHGKVEVIGTDESQEVPYTIR------QMGIYLVVDTDIGLVLL 1013
Query: 140 IDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGEQW 199
D + + LS + + CGLCGNF+ A +DF T+ ++ D +F NSW LS
Sbjct: 1014 WDKKTSIFINLSPEFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSWKLSPS--- 1070
Query: 200 CERASPPSSSCNISSGEMQKGLWEQCQLLKSTSVFARCHPLVDPEPFVALCEKTLCEC-- 257
C A P C ++ + +QC +L + FA CH V+P + C C C
Sbjct: 1071 CPDALAPKDPCT-ANPFRKSWAQKQCSILHGPT-FAACHAHVEPARYYEACVNDACACDS 1128
Query: 258 AGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVC----PAGM---EYRQCVSPCAR 310
G EC C A+ YA+ C + G+ + W S C C P G Y+ C PC R
Sbjct: 1129 GGDCECFCTAVAAYAQACHEVGLCV-SWRTPSICPLFCDYYNPEGQCEWHYQPCGVPCLR 1187
Query: 311 TCQSLHINEMCQERCVDGC--SC-PEGQLLDEGLCVESTECP-------CVHSGKRYPPG 360
TC++ + + ++GC C PE + DE CP C GK Y PG
Sbjct: 1188 TCRNPRGDCLRDVWGLEGCYPKCPPEAPIFDEDKMQCVATCPTPPLPPRCHVHGKSYRPG 1247
Query: 361 TSLSRD--CNTCICRNSQWICSNEECPGECLVTGQSHFKSFDNRYFTFSGICQYLLAR 416
+ D C +C+C C+ + C GQ F D Y T G + AR
Sbjct: 1248 AVVPSDKNCQSCLCTERGVECTYKAEACVCTYNGQ-RFHPGDVIYHTTDGTGGCISAR 1304
Score = 125 bits (313), Expect = 8e-28
Identities = 143/574 (24%), Positives = 214/574 (37%), Gaps = 122/574 (21%)
Query: 1939 TC-GCRWTC---PC--VCTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKEQD-LEVILHNG 1991
TC G RW+C PC C+ H TFDG+ + + G CSYVL + + V+
Sbjct: 417 TCSGGRWSCQEVPCPGTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSAFTVLAELR 476
Query: 1992 ACSPGARQGCMKSIEVKHSALS--VELHSDMEVTVNGRLVSVPYVGGNMEVNVYGAIMHE 2049
C + C+KS+ + + V + + EV +N +P N+ + +
Sbjct: 477 RCGLTDSETCLKSVTLSLDGVQTVVVIKASGEVFLNQIYTQLPISAANVTI-FRPSTFFI 535
Query: 2050 VRFNHLG-HIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWK 2108
+ LG + + +QL+PK +T GLCG + A+DF G V
Sbjct: 536 IAQTSLGLQLNLQLVPTMQLFMQLAPK-LRGQTCGLCGNFNSIQADDFRTLSGVVEATAA 594
Query: 2109 TLVQEWTVQRPGQTCQPILEEQC--LVPDSSHCQVLLLPL------FAECHKVLAPATFY 2160
+ Q + E+ C V + + Q L F CH + P T+Y
Sbjct: 595 AFFNTFKTQAACPNIRNSFEDPCSLSVENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYY 654
Query: 2161 AICQQDSCHQEQ----VCEVIASYAHLCRTNGVCVDWRTPDFCA---MSCPPSLVYNH-- 2211
+ C D+C+ E+ +C ++SY H C GV + C +CP S+ Y++
Sbjct: 655 SNCMFDTCNCERSEDCLCAALSSYVHACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHYHV 714
Query: 2212 --CEHGCPRHCDGNVS-SCGDHPSEGCFCPPDKVMLE-GSCVPEEACTQCIGEDGVQHQF 2267
C+ C +G+++ S G P +GC CP + + G CV C C +
Sbjct: 715 STCQPTCRSLSEGDITCSVGFIPVDGCICPKGTFLDDTGKCVQASNC-PCYHRGSM---- 769
Query: 2268 LEAWVPD----HQPCQICTCLSGRKVNCTTQPCPTAKAPTCGLCEVARLRQNADQCCPEY 2323
+P+ H ICTC G K++C P AP C V +
Sbjct: 770 ----IPNGESVHDSGAICTCTHG-KLSCIGGQAP---APVCAAPMVF------------F 809
Query: 2324 ECVCDPVSCDLPPVPHCERGLQPTLTNPGECRPNFTCACRKEECKRVSPPSCPPHRLPTL 2383
+C R P T G C+K SC H L
Sbjct: 810 DC----------------RNATPGDTGAG---------CQK---------SC--HTL--- 830
Query: 2384 RKTQCCDEYECACNCVNSTVSCPLGYLASTATNDCGCTTTTCLPDKVCVHRSTIYPVGQF 2443
C +C CV CP G +A + GC T P CVH Y GQ
Sbjct: 831 --DMTCYSPQCVPGCV-----CPDGLVAD---GEGGCITAEDCP---CVHNEASYRAGQT 877
Query: 2444 WEEGCDVCTCTDMEDAVMGLRVAQCSQKPCEDSC 2477
GC+ CTC R+ +C+ PC +C
Sbjct: 878 IRVGCNTCTCDS--------RMWRCTDDPCLATC 903
Score = 125 bits (313), Expect = 8e-28
Identities = 113/402 (28%), Positives = 157/402 (39%), Gaps = 64/402 (15%)
Query: 1939 TCGC---RWTC---PCV--CTGSSTRHIVTFDGQNFKLTGSCSYVLFQNK-------EQD 1983
TC C W C PC+ C H +TFDGQ++ G C Y L QN +
Sbjct: 884 TCTCDSRMWRCTDDPCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDS 943
Query: 1984 LEVILHNGACSPGARQGCMKSIEVKHSALSVEL-HSDMEVTVNGRLVSVPYVGGNMEVNV 2042
V+ N C C K+I++ ++L H +EV VPY M + +
Sbjct: 944 FRVVTENVPCGTTGTT-CSKAIKIFLGGFELKLSHGKVEVIGTDESQEVPYTIRQMGIYL 1002
Query: 2043 YGAIMHEVRFNHLGHIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGT 2102
V +G + + + + F + LSP+ F + GLCG D+ NDF R +
Sbjct: 1003 -------VVDTDIGLVLLWDKKTSIF-INLSPE-FKGRVCGLCGNFDDIAVNDFATRSRS 1053
Query: 2103 VTTDWKTLVQEWTVQRPGQTCQPIL--EEQCLVPD------SSHCQVLLLPLFAECHKVL 2154
V D W + +C L ++ C C +L P FA CH +
Sbjct: 1054 VVGDVLEFGNSWKLS---PSCPDALAPKDPCTANPFRKSWAQKQCSILHGPTFAACHAHV 1110
Query: 2155 APATFYAICQQDSC------HQEQVCEVIASYAHLCRTNGVCVDWRTPDFCAMSC----P 2204
PA +Y C D+C E C +A+YA C G+CV WRTP C + C P
Sbjct: 1111 EPARYYEACVNDACACDSGGDCECFCTAVAAYAQACHEVGLCVSWRTPSICPLFCDYYNP 1170
Query: 2205 PSLV---YNHCEHGCPRHCDGNVSSC--GDHPSEGCF--CPP-------DKVMLEGSCVP 2250
Y C C R C C EGC+ CPP DK+ +C
Sbjct: 1171 EGQCEWHYQPCGVPCLRTCRNPRGDCLRDVWGLEGCYPKCPPEAPIFDEDKMQCVATCPT 1230
Query: 2251 EEACTQCIGEDGVQHQFLEAWVPDHQPCQICTCLSGRKVNCT 2292
+C G ++ A VP + CQ C C + R V CT
Sbjct: 1231 PPLPPRC-HVHGKSYR-PGAVVPSDKNCQSCLC-TERGVECT 1269
Score = 109 bits (273), Expect = 3e-23
Identities = 102/371 (27%), Positives = 161/371 (43%), Gaps = 41/371 (11%)
Query: 1949 VCTGSSTRHIVTFDGQNFKLTGSCSYVLFQN---KEQDLEVILHNGACSPGARQGCMKSI 2005
VC+ + H TFDG F+ G C+YV ++ +D + L S + + +
Sbjct: 80 VCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRR---SQESAAPTLSRV 136
Query: 2006 EVKHSALSVELHSDMEVTVNGRLVSVPYVGGNMEVNVYGAIMH-EVRFNHLGHIFTFTPQ 2064
+K + ++L V VNG V +P+ + + + E R LG + +
Sbjct: 137 LMKVDGVVIQLTKG-SVLVNGHPVLLPFSQSGVLIQQSSSYTKVEAR---LGLVLMWN-H 191
Query: 2065 NNEFQLQLSPKTFASKTYGLCGICDENG---ANDFMLRDGTVTTDWKTLVQEWTVQRPGQ 2121
++ L+L K +A+KT GLCG D NG ++ + + +T +Q+ + P +
Sbjct: 192 DDSLLLELDTK-YANKTCGLCG--DFNGMPVVSELLSHNTKLTPMEFGNLQK--MDDPTE 246
Query: 2122 TCQPILEE---QCLVPDSSHCQVLLLPLFAECHKVLAPATFYAICQQDSCHQEQ------ 2172
CQ + E C ++L LF+ C ++ ++ C+QD C E
Sbjct: 247 QCQDPVPEPPRNCSTGFGICEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDLLSC 306
Query: 2173 VCEVIASYAHLC-RTNGVCVDWRTPDFCAMSCPPSLVYNHCEHGCPRHCDGNVSS--CGD 2229
VC +A Y+ C G+ DWR PDFC CP ++ Y+ C C C S C D
Sbjct: 307 VCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCSNQEHSRACED 366
Query: 2230 HPSEGCFCPPDKVM---LEGSCVPEEACTQCIGEDGVQHQFLEAWVPDHQPCQICTCLSG 2286
H GCFCP V+ + CVP C C+ +G + + D C CTC SG
Sbjct: 367 HCVAGCFCPEGTVLDDIGQTGCVPVSKCA-CV-YNGAAYAPGATYSTD---CTNCTC-SG 420
Query: 2287 RKVNCTTQPCP 2297
+ +C PCP
Sbjct: 421 GRWSCQEVPCP 431
Score = 38.9 bits (89), Expect = 0.072
Identities = 65/280 (23%), Positives = 96/280 (34%), Gaps = 57/280 (20%)
Query: 2318 QCCPEYECVC---DPVSCDLPPVPHCER------GLQPTLTNPGECRPNFTCACRKEECK 2368
+ C + C C D +SC + R GL P C + EC+
Sbjct: 289 EACRQDLCFCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECR 348
Query: 2369 RVSPPSCPPHRLPTLRKTQCCDEYECACNCVNSTVSCPLGYLASTATNDCGCTTTTCLPD 2428
+C ++ C+++ C C CP G T +D G T +
Sbjct: 349 SPCADTCSNQE-----HSRACEDH-CVAGCF-----CPEG----TVLDDIGQTGCVPVSK 393
Query: 2429 KVCVHRSTIYPVGQFWEEGCDVCTCTDMEDAVMGLRVAQCSQKPCEDSCR---------- 2478
CV+ Y G + C CTC+ G R + C + PC +C
Sbjct: 394 CACVYNGAAYAPGATYSTDCTNCTCS-------GGRWS-CQEVPCPGTCSVLGGAHFSTF 445
Query: 2479 SGFTYVLHEGEC----CGRCLPSACEVVTGSPR---GDSQSSWKSVGSQWASPENPCLIN 2531
G Y +H G+C C SA V+ R DS++ KSV + +I
Sbjct: 446 DGKQYTVH-GDCSYVLTKPCDSSAFTVLAELRRCGLTDSETCLKSVTLSLDGVQTVVVI- 503
Query: 2532 ECVRVKEEVFIQQRNVSCPQLEVPVC---PSGFQLSCKTS 2568
+ EVF+ Q P V PS F + +TS
Sbjct: 504 ---KASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTS 540
Score = 38.1 bits (87), Expect = 0.12
Identities = 25/73 (34%), Positives = 31/73 (42%), Gaps = 16/73 (21%)
Query: 2557 CPSGFQLS-CKTSACCPSCRCERMEACMLNGTVIGPGKTVMIDVCTTCRCMVQVGVISGF 2615
CP G L + C P +C AC+ NG PG T D CT C C SG
Sbjct: 374 CPEGTVLDDIGQTGCVPVSKC----ACVYNGAAYAPGATYSTD-CTNCTC-------SGG 421
Query: 2616 KLECRKTTCNPCP 2628
+ C++ PCP
Sbjct: 422 RWSCQEV---PCP 431
>gi|161019170 mucin 5AC [Homo sapiens]
Length = 6207
Score = 761 bits (1964), Expect = 0.0
Identities = 424/1269 (33%), Positives = 607/1269 (47%), Gaps = 115/1269 (9%)
Query: 35 CSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRSFSIIGDFQNGKRVSLSVYLGEFFDI 94
CS +G TFDG ++ F G C+Y+ + C+ + G S V
Sbjct: 733 CSTWGDFHYKTFDGDVFRFPGLCNYVFSEHCRAAYEDFNVQLRRGLVGSRPVVTRVVIKA 792
Query: 95 HLFV----NGTVTQGDQRVSMPYASKGLYLETEAGYYKLSGEAYGFVARIDGSGNFQVLL 150
V NG+V QR +PY+ GL +E Y K+S +G + + L
Sbjct: 793 QGLVLEASNGSVLINGQREELPYSRTGLLVEQSGDYIKVSIRLV-LTFLWNGEDSALLEL 851
Query: 151 SDRYFNKTCGLCGNFN-IFAEDDFMTQEGTLTSDPYDFANSWALSSGEQWCERASP-PSS 208
+Y N+TCGLCG+FN + A ++F LT P F N L + C P P+
Sbjct: 852 DPKYANQTCGLCGDFNGLPAFNEFYAHNARLT--PLQFGNLQKLDGPTEQCPDPLPLPAG 909
Query: 209 SCNISSGEMQKGLWEQCQLLKSTSVFARCHPLVDPEPFVALCEKTLCECAGGLECACPAL 268
+C G C FA CH LVD ++A C + LC C C C
Sbjct: 910 NCTDEEGI--------CHRTLLGPAFAECHALVDSTAYLAACAQDLCRCP---TCPCATF 958
Query: 269 LEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCARTCQSLHINEMCQERCVDG 328
+EY+R CA G W C CP M++++C SPC TC + ++C++ CVDG
Sbjct: 959 VEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTCSNPQRAQLCEDHCVDG 1018
Query: 329 CSCPEGQ---LLDE---GLCVESTECPCVHSGKRYPPGTSLSRDCNTCICRNSQWICSNE 382
C CP G+ +LD+ C+ +CPC H G+ Y PGTS + C++C C W C +
Sbjct: 1019 CFCPPGRSCTVLDDITHSGCLPLGQCPCTHGGRTYSPGTSFNTTCSSCTCSGGLWQCQDL 1078
Query: 383 ECPGECLVTGQSHFKSFDNRYFTFSGICQYLLARDCQDHSFSIVIETVQCADDRDAVCTR 442
CPG C V G +H ++D + + G C Y+L++ C D SF+++ E +C + C +
Sbjct: 1079 PCPGTCSVQGGAHISTYDEKLYDLHGDCSYVLSKKCADSSFTVLAELRKCGLTDNENCLK 1138
Query: 443 SVTVRLPGLHNSLVKLKHGAGVAMDGQDVQLPLLKGDLRI--QHTVTASVRLSYGEDLQM 500
+VT+ L G ++ ++++ GV ++ QLPL ++ + + V+ G L +
Sbjct: 1139 AVTLSLDG-GDTAIRVQADGGVFLNSIYTQLPLSAANITLFTPSSFFIVVQTGLGLQLLV 1197
Query: 501 DWDGRGRLLVKLSPVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWKLHGDCQ 560
++ V+L P + G+ CGLCGN+N NQ DDF SG+ E F N WK C
Sbjct: 1198 QLVPLMQVFVRLDPAHQGQMCGLCGNFNQNQADDFTALSGVVEATGAAFANTWKAQAACA 1257
Query: 561 DLQKQHSDPCALNPRMTRFSEEACAVLTSPT--FEACHRAVSPLPYLRNCRYDVCSCSDG 618
+ + DPC+L+ ++ C+ LT P F CH ++P P+ NC +D C+C
Sbjct: 1258 NARNSFEDPCSLSVENENYARHWCSRLTDPNSAFSRCHSIINPKPFHSNCMFDTCNCERS 1317
Query: 619 RECLCGALASYAAACAGRGVRVA-WREPGRCEL---NCPKGQVYLQCGTPCNLTCRSLSY 674
+CLC AL+SY ACA +GV+++ WR+ G C NCPK Q Y C TCR LS
Sbjct: 1318 EDCLCAALSSYVHACAAKGVQLSDWRD-GVCTKYMQNCPKSQRYAYVVDACQPTCRGLSE 1376
Query: 675 PDEECNEACL--EGCFCPPGLYMDERGDCVPKAQCPCYYDGEIFQPEDIFSDHHTMCYCE 732
D C+ + + +GC CP G ++++ G CVP +CPCY G + P ++ D +C C
Sbjct: 1377 ADVTCSVSFVPVDGCTCPAGTFLNDAGACVPAQECPCYAHGTVLAPGEVVHDEGAVCSCT 1436
Query: 733 DGFMHCTMSGVPGSLLPDAVLSSPLSHRSKRSLSCRPPMVKLVCPADNLRAEGLECTKTC 792
G + C L ++S C PMV L C + G EC ++C
Sbjct: 1437 GGKLSC------------------LGASLQKSTGCAAPMVYLDCSNSSAGTPGAECLRSC 1478
Query: 793 QNYDLECMSMGCVSGCLCPPGMVRH-ENRCVALERCPCFHQGKEYAPGETVKIGCNTCVC 851
D+ C S CVSGC+CPPG+V C+A E CPC H Y PGET+++ CNTC C
Sbjct: 1479 HTLDVGCFSTHCVSGCVCPPGLVSDGSGGCIAEEDCPCVHNEATYKPGETIRVDCNTCTC 1538
Query: 852 RDRKWNCTDHVCDATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNP--GTFRILV 909
R+R+W C+ +C TC G H++TFDG +Y F G C+Y+L QDYCG N GTFRI+
Sbjct: 1539 RNRRWECSHRLCLGTCVAYGDGHFITFDGDRYSFEGSCEYILAQDYCGDNTTHGTFRIVT 1598
Query: 910 GNKGCSHPSVKCKKRVTILVE---GGEIELFDGEVNVKRPMK------------------ 948
N C C K + + VE + D N P +
Sbjct: 1599 ENIPCGTTGTTCSKAIKLFVEVRTAPAVSTPDPAANEPAPREASVGFRQRLPPLQSYELI 1658
Query: 949 -DETHFEVVESG---------RYI---ILLLGKALSVVWDRHLSISVVLKQTYQEKVCGL 995
E F+ V G RY+ +++ ++V WDR S+ + L Q Y+ +VCGL
Sbjct: 1659 LQEGTFKAVARGPGGDPPYKIRYMGIFLVIETHGMAVSWDRKTSVFIRLHQDYKGRVCGL 1718
Query: 996 CGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKVSSQCADTRKVPLDSSPATCHNNIMKQTM 1055
CGNFD ND + + V D ++FGNSWK+S C D P D C N +++
Sbjct: 1719 CGNFDDNAINDFATRSRSVVGDALEFGNSWKLSPSCPDA-LAPKD----PCTANPFRKSW 1773
Query: 1056 VDSSCRILTSDVFQDCNKLVDPEPYLDVCIYDTCSCESIGDCACFCDTIAAYAHVCAQHG 1115
C IL F C VD Y + C+ D C+C+S GDC CFC +AAYA C G
Sbjct: 1774 AQKQCSILHGPTFAACRSQVDSTKYYEACVNDACACDSGGDCECFCTAVAAYAQACHDAG 1833
Query: 1116 KVVTWRTATLCPQSCEERNLRENGYECEWRYNSCAPACQVTCQHPEPLACPVQC--VEGC 1173
V+WRT CP C+ N CEW Y C C TC++P C V +EGC
Sbjct: 1834 LCVSWRTPDTCPLFCDFYNPHGG---CEWHYQPCGAPCLKTCRNPSG-HCLVDLPGLEGC 1889
Query: 1174 HAHCPPGK-ILDELLQTCVDPEDCPVCEVAGRRFASGKKVTLNPSDPEHCQICHCDVVNL 1232
+ CPP + +E CV C + G + G +V E+CQ C+C +
Sbjct: 1890 YPKCPPSQPFFNEDQMKCV--AQCGCYDKDGNYYDVGARV----PTAENCQSCNCTPSGI 1943
Query: 1233 TC----EAC 1237
C EAC
Sbjct: 1944 QCAHSLEAC 1952
Score = 305 bits (781), Expect = 4e-82
Identities = 180/570 (31%), Positives = 276/570 (48%), Gaps = 31/570 (5%)
Query: 35 CSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQK--RSFSI-IGDFQNGKRVSLSVYLGEF 91
CS +GS TFDG ++ F G C+Y+ + C F+I + Q +LS L +
Sbjct: 81 CSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRSQESAAPTLSRVLMKV 140
Query: 92 FDIHL-FVNGTVTQGDQRVSMPYASKGLYLETEAGYYKLSGEAYGFVARIDGSGNFQVLL 150
+ + G+V V +P++ G+ ++ + Y K+ G V + + + L
Sbjct: 141 DGVVIQLTKGSVLVNGHPVLLPFSQSGVLIQQSSSYTKVEARL-GLVLMWNHDDSLLLEL 199
Query: 151 SDRYFNKTCGLCGNFN-IFAEDDFMTQEGTLTSDPYDFANSWALSSGEQWCERASP-PSS 208
+Y NKTCGLCG+FN + + ++ LT P +F N + + C+ P P
Sbjct: 200 DTKYANKTCGLCGDFNGMPVVSELLSHNTKLT--PMEFGNLQKMDDPTEQCQDPVPEPPR 257
Query: 209 SCNISSGEMQKGLWEQCQLLKSTSVFARCHPLVDPEPFVALCEKTLCECAGG--LECACP 266
+C+ G C+ L +F+ C LVD ++ C + LC C L C C
Sbjct: 258 NCSTGFGI--------CEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDLLSCVCH 309
Query: 267 ALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCARTCQSLHINEMCQERCV 326
L EY+R C G + W C CP M+Y +C SPCA TC + + C++ CV
Sbjct: 310 TLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCSNQEHSRACEDHCV 369
Query: 327 DGCSCPEGQLLDE---GLCVESTECPCVHSGKRYPPGTSLSRDCNTCICRNSQWICSNEE 383
GC CPEG +LD+ CV ++C CV++G Y PG + S DC C C +W C
Sbjct: 370 AGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATYSTDCTNCTCSGGRWSCQEVP 429
Query: 384 CPGECLVTGQSHFKSFDNRYFTFSGICQYLLARDCQDHSFSIVIETVQCADDRDAVCTRS 443
CPG C V G +HF +FD + +T G C Y+L + C +F+++ E +C C +S
Sbjct: 430 CPGTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSAFTVLAELRRCGLTDSETCLKS 489
Query: 444 VTVRLPGLHNSLVKLKHGAGVAMDGQDVQLPLLKGDLRIQHTVTASV--RLSYGEDLQMD 501
VT+ L G ++V +K V ++ QLP+ ++ I T + + S G L +
Sbjct: 490 VTLSLDGA-QTVVVIKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQ 548
Query: 502 WDGRGRLLVKLSPVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWKLHGDCQD 561
+L ++L+P G+TCGLCGN+N Q DDF T SG+ E F N +K C +
Sbjct: 549 LVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTFKTQAACPN 608
Query: 562 LQKQHSDPCALN----PRMTRFSEEACAVL 587
++ DPC+L+ PRM + AC L
Sbjct: 609 IRNSFEDPCSLSVENAPRMG--APSACRTL 636
Score = 220 bits (561), Expect = 1e-56
Identities = 193/690 (27%), Positives = 278/690 (40%), Gaps = 103/690 (14%)
Query: 1887 KRPGDVWTLPDQCHTVTCQPDGQTLLKSHRVNCDRGLRPSCPNSQSPVKVEET---CGCR 1943
++ + WTL + C C D + +L + + +C N P+KV + C
Sbjct: 5336 RQVNETWTL-ENCTVARCVGDNRVVLLDPKPVAN----VTCVNKHLPIKVSDPSQPCDFH 5390
Query: 1944 WTCPCVCTGS-------------STRHIVTFDGQNFKLTGSCSYVLFQN---KEQDLEVI 1987
+ C C C G H TFDG ++ G+C+YVL + + +L +
Sbjct: 5391 YECECECVGGRGITPGAGICSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLY 5450
Query: 1988 LHNGACSPGARQG-----CMKSIEVKHSALSVELHSDMEVTVNGRLV---SVPYVGG--- 2036
L N C+ A C +++ + + ++ + L M L+ +P G
Sbjct: 5451 LDNHYCTASATAAAAAARCPRALSIHYKSMDIVLTVTMVHGKEEGLILFDQIPVSSGFSK 5510
Query: 2037 -NMEVNVYGAIMHEVRFNHLGHIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGAND 2095
+ V+V G V LG TF Q FQ +L F + T G CG C N +D
Sbjct: 5511 NGVLVSVLGTTTMRVDIPALGVSVTFNGQ--VFQARLPYSLFHNNTEGQCGTCTNNQRDD 5568
Query: 2096 FMLRDGTVTTDWKTLVQEWTV---QRPG--------QTCQPILEEQCL-----VPDSSHC 2139
+ RDGT K + + W V ++ G T P P C
Sbjct: 5569 CLQRDGTTAASCKDMAKTWLVPDSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQPLC 5628
Query: 2140 QVLLLPLFAECHKVLAPATFYAICQQDSC--HQEQVCEVIASYAHLCRTNGVCVDWR--T 2195
++L +FAECH ++ P F+ C D C E C+ + +YA LCR GVC DWR T
Sbjct: 5629 DLMLSQVFAECHNLVPPGPFFNACISDHCRGRLEVPCQSLEAYAELCRARGVCSDWRGAT 5688
Query: 2196 PDFCAMSCPPSLVYNHCEHGCPRHCDG-NVSSCGDHPSEGCFCPPDKVMLE---GSCVPE 2251
C ++CPP+ VY C P C+ N S + +EGCFCP D+++ G CV
Sbjct: 5689 GGLCDLTCPPTKVYKPCGPIQPATCNSRNQSPQLEGMAEGCFCPEDQILFNAHMGICV-- 5746
Query: 2252 EACTQCIGEDGVQHQFLEAWVPDHQPCQICTCLSGR-KVNCTTQPCPT-AKAPTC---GL 2306
+AC C+G DG E WV + CQ C C G V C PC + P C G
Sbjct: 5747 QAC-PCVGPDGFPKFPGERWVSN---CQSCVCDEGSVSVQCKPLPCDAQGQPPPCNRPGF 5802
Query: 2307 CEVARLRQNADQCCPEYECVCDPVSCDLPPVPHCERGLQPTLT-NPGECRPNFTCACRKE 2365
V R R + CCPE CVC+ +C +P C G + T G+C P F CR +
Sbjct: 5803 VTVTRPRAE-NPCCPETVCVCNTTTCP-QSLPVCPPGQESICTQEEGDCCPTF--RCRPQ 5858
Query: 2366 ECK---------RVSPPSCPPHRLPTLRKTQCCDEYECACNCVNSTVSCPLGYLASTATN 2416
C P + P H L +C + N+T +CP G+
Sbjct: 5859 LCSYNGTFYGVGATFPGALPCHMCTCLSGDTQDPTVQCQEDACNNT-TCPQGFEYKRVAG 5917
Query: 2417 DC--GCTTTTCL-PDKVCVHRSTIYPVGQFWEEGCDVCTCTDMEDAVMGLRVAQCSQKPC 2473
C C T CL PD V + + + C V C +A G+ + C
Sbjct: 5918 QCCGECVQTACLTPDGQPVQLNETWVNSHV--DNCTVYLC----EAEGGVHLLTPQPASC 5971
Query: 2474 ED--SCRSGFTYVLHEGECCGRCLPSACEV 2501
D SCR L + CC C +C+V
Sbjct: 5972 PDVSSCRGS----LRKTGCCYSCEEDSCQV 5997
Score = 208 bits (529), Expect = 7e-53
Identities = 146/507 (28%), Positives = 222/507 (43%), Gaps = 57/507 (11%)
Query: 769 PPMVKLVCPADNLRAE-GLECTKTCQNYD-LECMSMGCVSGCLCPPGM-------VRHEN 819
P + CP + E G CT TC N + CV GC CPPG + H
Sbjct: 978 PELCPRTCPLNMQHQECGSPCTDTCSNPQRAQLCEDHCVDGCFCPPGRSCTVLDDITHSG 1037
Query: 820 RCVALERCPCFHQGKEYAPGETVKIGCNTCVCRDRKWNCTDHVCDATCSTIGMAHYLTFD 879
C+ L +CPC H G+ Y+PG + C++C C W C D C TCS G AH T+D
Sbjct: 1038 -CLPLGQCPCTHGGRTYSPGTSFNTTCSSCTCSGGLWQCQDLPCPGTCSVQGGAHISTYD 1096
Query: 880 GLKYLFPGECQYVLVQDYCGSNPGTFRILVGNKGCS-HPSVKCKKRVTILVEGGEIEL-- 936
Y G+C YVL + S+ F +L + C + C K VT+ ++GG+ +
Sbjct: 1097 EKLYDLHGDCSYVLSKKCADSS---FTVLAELRKCGLTDNENCLKAVTLSLDGGDTAIRV 1153
Query: 937 ------FDGEVNVKRPMKDETHFEVVESGRYIILLLGKALSVVWDRH--LSISVVLKQTY 988
F + + P+ S +I++ G L ++ + + V L +
Sbjct: 1154 QADGGVFLNSIYTQLPLSAANITLFTPSSFFIVVQTGLGLQLLVQLVPLMQVFVRLDPAH 1213
Query: 989 QEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKVSSQCADTRKVPLDSSPATCHN 1048
Q ++CGLCGNF+ Q +D T+ + VE F N+WK + CA+ R +S C
Sbjct: 1214 QGQMCGLCGNFNQNQADDFTALSGVVEATGAAFANTWKAQAACANAR----NSFEDPCSL 1269
Query: 1049 NIMKQTMVDSSCRILT--SDVFQDCNKLVDPEPYLDVCIYDTCSCESIGDCACFCDTIAA 1106
++ + C LT + F C+ +++P+P+ C++DTC+CE D C C +++
Sbjct: 1270 SVENENYARHWCSRLTDPNSAFSRCHSIINPKPFHSNCMFDTCNCERSED--CLCAALSS 1327
Query: 1107 YAHVCAQHG-KVVTWR--TATLCPQSCEERNLRENGYECEWRYNSCAPACQVTCQ--HPE 1161
Y H CA G ++ WR T Q+C + RY ACQ TC+
Sbjct: 1328 YVHACAAKGVQLSDWRDGVCTKYMQNCPKSQ----------RYAYVVDACQPTCRGLSEA 1377
Query: 1162 PLACPVQCVEGCHAHCPPGKILDELLQTCVDPEDCPVCEVAGRRFASGKKVTLNPSDPEH 1221
+ C V V CP G L++ CV ++CP C G A G+ V +
Sbjct: 1378 DVTCSVSFVPVDGCTCPAGTFLND-AGACVPAQECP-CYAHGTVLAPGEVV------HDE 1429
Query: 1222 CQICHCDVVNLTC--EACQEPGGLVVP 1246
+C C L+C + Q+ G P
Sbjct: 1430 GAVCSCTGGKLSCLGASLQKSTGCAAP 1456
Score = 169 bits (429), Expect = 3e-41
Identities = 113/368 (30%), Positives = 165/368 (44%), Gaps = 24/368 (6%)
Query: 388 CLVTGQSHFKSFDNRYFTFSGICQYLLARDCQD--HSFSIVIETVQCADDRDAVCTRSVT 445
C G H+K+FD F F G+C Y+ + C F+I + Q + A V
Sbjct: 81 CSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRSQ---ESAAPTLSRVL 137
Query: 446 VRLPGLHNSLVKLKHGAGVAMDGQDVQLPLLKGDLRIQHTVTASVRLSYGEDLQMDWDGR 505
+++ G+ L K V ++G V LP + + IQ + ++ ++ L + W+
Sbjct: 138 MKVDGVVIQLTK----GSVLVNGHPVLLPFSQSGVLIQQS-SSYTKVEARLGLVLMWNHD 192
Query: 506 GRLLVKLSPVYAGKTCGLCGNYNGNQG-DDFLTPSGLAEPRVEDFGNAWKLHGDCQDLQK 564
LL++L YA KTCGLCG++NG + L+ + P +FGN K+ D +
Sbjct: 193 DSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTPM--EFGNLQKM----DDPTE 246
Query: 565 QHSDPCALNPRMTRFSEEACA-VLTSPTFEACHRAVSPLPYLRNCRYDVCSCSDGR--EC 621
Q DP PR C +L F C V YL CR D+C C D C
Sbjct: 247 QCQDPVPEPPRNCSTGFGICEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDLLSC 306
Query: 622 LCGALASYAAACA-GRGVRVAWREPGRCELNCPKGQVYLQCGTPCNLTCRSLSYPDEECN 680
+C LA Y+ C G+ WR P C CP Y +C +PC TC + + C
Sbjct: 307 VCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCSNQEH-SRACE 365
Query: 681 EACLEGCFCPPGLYMDERGD--CVPKAQCPCYYDGEIFQPEDIFSDHHTMCYCEDGFMHC 738
+ C+ GCFCP G +D+ G CVP ++C C Y+G + P +S T C C G C
Sbjct: 366 DHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATYSTDCTNCTCSGGRWSC 425
Query: 739 TMSGVPGS 746
PG+
Sbjct: 426 QEVPCPGT 433
Score = 155 bits (391), Expect = 7e-37
Identities = 118/387 (30%), Positives = 169/387 (43%), Gaps = 47/387 (12%)
Query: 867 CSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPGTFRILVGNKGCSHPSVKCKKRVT 926
CST G HY TFDG + FPG C YV ++CG+ F I + + + RV
Sbjct: 81 CSTWGSFHYKTFDGDVFRFPGLCNYVF-SEHCGAAYEDFNIQL--RRSQESAAPTLSRVL 137
Query: 927 ILVEGGEIELFDGEVNVK-RPMK---DETHFEVVESGRYIILLLGKALSVVWDRHLSISV 982
+ V+G I+L G V V P+ ++ + +S Y + L ++W+ S+ +
Sbjct: 138 MKVDGVVIQLTKGSVLVNGHPVLLPFSQSGVLIQQSSSYTKVEARLGLVLMWNHDDSLLL 197
Query: 983 VLKQTYQEKVCGLCGNFDGIQN-NDLTSSNLQVEEDPVDFGNSWKV---SSQCADTRKVP 1038
L Y K CGLCG+F+G+ ++L S N ++ P++FGN K+ + QC D P
Sbjct: 198 ELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLT--PMEFGNLQKMDDPTEQCQD----P 251
Query: 1039 LDSSPATCHNNIMKQTMVDSSCR-ILTSDVFQDCNKLVDPEPYLDVCIYDTCSCESIGDC 1097
+ P C C +L +F C LVD YL+ C D C CE
Sbjct: 252 VPEPPRNCSTGF-------GICEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDLL 304
Query: 1098 ACFCDTIAAYAHVCAQHGKV-VTWRTATLCPQSCEERNLRENGYECEWRYNSCAPACQVT 1156
+C C T+A Y+ C G + WR CPQ C +Y+ C C T
Sbjct: 305 SCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPN----------NMQYHECRSPCADT 354
Query: 1157 CQHPE-PLACPVQCVEGCHAHCPPGKILDELLQT-CVDPEDCPVCEVAGRRFASGKKVTL 1214
C + E AC CV GC CP G +LD++ QT CV C C G +A G +
Sbjct: 355 CSNQEHSRACEDHCVAGC--FCPEGTVLDDIGQTGCVPVSKC-ACVYNGAAYAPGATYST 411
Query: 1215 NPSDPEHCQICHCDVVNLTCEACQEPG 1241
+ C C C +C+ PG
Sbjct: 412 D------CTNCTCSGGRWSCQEVPCPG 432
Score = 146 bits (368), Expect = 3e-34
Identities = 119/396 (30%), Positives = 172/396 (43%), Gaps = 75/396 (18%)
Query: 867 CSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPGTFRI-----LVGNKGCSHPSVKC 921
CST G HY TFDG + FPG C YV ++C + F + LVG S P V
Sbjct: 733 CSTWGDFHYKTFDGDVFRFPGLCNYVF-SEHCRAAYEDFNVQLRRGLVG----SRPVVT- 786
Query: 922 KKRVTILVEGGEIELFDGEVNVKRPMKD----ETHFEVVESGRYIILLLGKALSVVWDRH 977
RV I +G +E +G V + ++ T V +SG YI + + L+ +W+
Sbjct: 787 --RVVIKAQGLVLEASNGSVLINGQREELPYSRTGLLVEQSGDYIKVSIRLVLTFLWNGE 844
Query: 978 LSISVVLKQTYQEKVCGLCGNFDGIQN-NDLTSSNLQVEEDPVDFGNSWKV---SSQCAD 1033
S + L Y + CGLCG+F+G+ N+ + N ++ P+ FGN K+ + QC D
Sbjct: 845 DSALLELDPKYANQTCGLCGDFNGLPAFNEFYAHNARL--TPLQFGNLQKLDGPTEQCPD 902
Query: 1034 TRKVPLDSSPATCHNNIMKQTMVDSSCRILTSDVFQDCNKLVDPEPYLDVCIYDTCSCES 1093
+PL + T I +T L F +C+ LVD YL C D C C +
Sbjct: 903 --PLPLPAGNCTDEEGICHRT--------LLGPAFAECHALVDSTAYLAACAQDLCRCPT 952
Query: 1094 IGDCACFCDTIAAYAHVCAQ-HGKVVTWRTATLCPQSCEERNLRENGYECEWRYNSCAPA 1152
C C T Y+ CA G+ WR LCP++C ++ C
Sbjct: 953 -----CPCATFVEYSRQCAHAGGQPRNWRCPELCPRTC----------PLNMQHQECGSP 997
Query: 1153 CQVTCQHPE-PLACPVQCVEGCHAHCPPGK---ILDELLQT-CVDPEDCPVCEVAGRRFA 1207
C TC +P+ C CV+GC CPPG+ +LD++ + C+ CP C GR ++
Sbjct: 998 CTDTCSNPQRAQLCEDHCVDGC--FCPPGRSCTVLDDITHSGCLPLGQCP-CTHGGRTYS 1054
Query: 1208 SGKKVTLNPSDPEHCQICHCDVVNLTCEACQEPGGL 1243
G N TC +C GGL
Sbjct: 1055 PGTS------------------FNTTCSSCTCSGGL 1072
Score = 143 bits (360), Expect = 3e-33
Identities = 119/413 (28%), Positives = 170/413 (41%), Gaps = 53/413 (12%)
Query: 2419 GCTTTTCLPDKVCVHRSTIYPVG----------QFWEEGCDVCTCTDMEDAVMGLRVAQC 2468
G TC P KV I P + EGC + +A MG+ V C
Sbjct: 5690 GLCDLTCPPTKVYKPCGPIQPATCNSRNQSPQLEGMAEGCFCPEDQILFNAHMGICVQAC 5749
Query: 2469 S--------QKPCEDSCRSGFTYVLHEGECCGRCLPSACEVVTGSPRGDSQSSWKSVGSQ 2520
+ P E + + V EG +C P C+ G P ++ + +V
Sbjct: 5750 PCVGPDGFPKFPGERWVSNCQSCVCDEGSVSVQCKPLPCDA-QGQPPPCNRPGFVTVTRP 5808
Query: 2521 WASPENPCLINECVRVKEEVFIQQRNVSCPQLEVPVCPSGFQLSC--KTSACCPSCRCER 2578
A ENPC E +CPQ +PVCP G + C + CCP+ RC R
Sbjct: 5809 RA--ENPCC--------PETVCVCNTTTCPQ-SLPVCPPGQESICTQEEGDCCPTFRC-R 5856
Query: 2579 MEACMLNGTVIGPGKTVMIDV-CTTCRCMVQVGVISGFKLECRKTTCN--PCPLGYKEEN 2635
+ C NGT G G T + C C C+ G ++C++ CN CP G++ +
Sbjct: 5857 PQLCSYNGTFYGVGATFPGALPCHMCTCLS--GDTQDPTVQCQEDACNNTTCPQGFEYKR 5914
Query: 2636 NTGECCGRCLPTACTIQLRGGQIMTLKRD--ETLQDGCDTHFCKVNERGEYFWEKRVTGC 2693
G+CCG C+ TAC GQ + L + D C + C+ E G + + C
Sbjct: 5915 VAGQCCGECVQTACLTP--DGQPVQLNETWVNSHVDNCTVYLCEA-EGGVHLLTPQPASC 5971
Query: 2694 PPFDEHKCLAEGGKIMKIPGTCCDTCEEPECNDITARLQYVKVGSCKSEVEVDIHYCQGK 2753
P D C G + K CC +CEE C R+ + E EV+I +C+G
Sbjct: 5972 P--DVSSCR---GSLRKTG--CCYSCEEDSCQ---VRINTTILWHQGCETEVNITFCEGS 6021
Query: 2754 CASKAMYSIDINDVQDQCSCCSPTRTEPMQVALHCTNGSVVYHEVLNAMECKC 2806
C + YS + +Q QC+CC R V LHC NGS + H +A++ C
Sbjct: 6022 CPGASKYSAEAQAMQHQCTCCQERRVHEETVPLHCPNGSAILHTYTHAVQVLC 6074
Score = 135 bits (341), Expect = 4e-31
Identities = 86/292 (29%), Positives = 134/292 (45%), Gaps = 22/292 (7%)
Query: 788 CTKTCQNYD-LECMSMGCVSGCLCPPGMVRHE---NRCVALERCPCFHQGKEYAPGETVK 843
C TC N + CV+GC CP G V + CV + +C C + G YAPG T
Sbjct: 351 CADTCSNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATYS 410
Query: 844 IGCNTCVCRDRKWNCTDHVCDATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPG 903
C C C +W+C + C TCS +G AH+ TFDG +Y G+C YVL + C S+
Sbjct: 411 TDCTNCTCSGGRWSCQEVPCPGTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKP-CDSS-- 467
Query: 904 TFRILVGNKGCS-HPSVKCKKRVTILVEGGEI--------ELFDGEVNVKRPMKDETHFE 954
F +L + C S C K VT+ ++G + E+F ++ + P+ +
Sbjct: 468 AFTVLAELRRCGLTDSETCLKSVTLSLDGAQTVVVIKASGEVFLNQIYTQLPI-SAANVT 526
Query: 955 VVESGRYIILL---LGKALSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSN 1011
+ + I+ LG L++ + + + L + + CGLCGNF+ IQ +D + +
Sbjct: 527 IFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLS 586
Query: 1012 LQVEEDPVDFGNSWKVSSQCADTRKVPLDSSPATCHNNIMKQTMVDSSCRIL 1063
VE F N++K + C + R D + N + S+CR L
Sbjct: 587 GVVEATAAAFFNTFKTQAACPNIRNSFEDPCSLSVEN--APRMGAPSACRTL 636
Score = 128 bits (322), Expect = 7e-29
Identities = 139/533 (26%), Positives = 202/533 (37%), Gaps = 72/533 (13%)
Query: 386 GECLVTGQSHFKSFDNRYFTFSGICQYLLARDCQDH--SFSIVIETVQCADDRDAV---- 439
G C + G SH+ +FD +TF G C Y+L R+ + S+ ++ C A
Sbjct: 5408 GICSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYLDNHYCTASATAAAAAA 5467
Query: 440 -CTRSVTVRLPGLHNSL-VKLKHGAG---VAMDGQDVQLPLLKGDLRIQHTVTASVRLSY 494
C R++++ + L V + HG + D V K + + T ++R+
Sbjct: 5468 RCPRALSIHYKSMDIVLTVTMVHGKEEGLILFDQIPVSSGFSKNGVLVSVLGTTTMRVDI 5527
Query: 495 GEDLQMDWDGRGRLLVKLSP--VYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNA 552
L + G++ P ++ T G CG NQ DD L G +D
Sbjct: 5528 -PALGVSVTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTAASCKDMAKT 5586
Query: 553 WKLHGDCQD---------LQKQHSDPCALNPRMTRF-SEEACAVLTSPTFEACHRAVSPL 602
W + +D + P + P T + C ++ S F CH V P
Sbjct: 5587 WLVPDSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQPLCDLMLSQVFAECHNLVPPG 5646
Query: 603 PYLRNCRYDVCSCSDGR-ECLCGALASYAAACAGRGVRVAWR--EPGRCELNCPKGQVYL 659
P+ C D C GR E C +L +YA C RGV WR G C+L CP +VY
Sbjct: 5647 PFFNACISDHCR---GRLEVPCQSLEAYAELCRARGVCSDWRGATGGLCDLTCPPTKVYK 5703
Query: 660 QCGTPCNLTCRSLSYPDEECNEACLEGCFCPPG--LYMDERGDCVPKAQCPCY-YDGEIF 716
CG TC S + + E EGCFCP L+ G CV CPC DG
Sbjct: 5704 PCGPIQPATCNSRNQSPQ--LEGMAEGCFCPEDQILFNAHMGICV--QACPCVGPDGFPK 5759
Query: 717 QPEDIFSDHHTMCYCEDGFMHCTMSGVPGSLLPDAVLSSPLSHRSKRSLSCRPPMVKLVC 776
P + + + C C++G + +P DA P + RP V +
Sbjct: 5760 FPGERWVSNCQSCVCDEGSVSVQCKPLP----CDAQGQPPPCN--------RPGFVTVTR 5807
Query: 777 PADNLRAEGLECTKTCQNYDLECMSMGCVSGC-LCPPGM----VRHENRCVALERCP--- 828
P RAE C +T C + C +CPPG + E C RC
Sbjct: 5808 P----RAENPCCPETV----CVCNTTTCPQSLPVCPPGQESICTQEEGDCCPTFRCRPQL 5859
Query: 829 CFHQGKEYAPGETV--KIGCNTCVC-----RDRKWNCTDHVCDATCSTIGMAH 874
C + G Y G T + C+ C C +D C + C+ T G +
Sbjct: 5860 CSYNGTFYGVGATFPGALPCHMCTCLSGDTQDPTVQCQEDACNNTTCPQGFEY 5912
Score = 113 bits (283), Expect = 2e-24
Identities = 102/366 (27%), Positives = 152/366 (41%), Gaps = 33/366 (9%)
Query: 1949 VCTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKE---QDLEVILHNGACSPGARQGCMKSI 2005
VC+ H TFDG F+ G C+YV ++ +D V L G G+R + +
Sbjct: 732 VCSTWGDFHYKTFDGDVFRFPGLCNYVFSEHCRAAYEDFNVQLRRGLV--GSRP-VVTRV 788
Query: 2006 EVKHSALSVELHSDMEVTVNGRLVSVPYVGGNMEVNVYGA-IMHEVRFNHLGHIFTFTPQ 2064
+K L +E S+ V +NG+ +PY + V G I +R + TF
Sbjct: 789 VIKAQGLVLEA-SNGSVLINGQREELPYSRTGLLVEQSGDYIKVSIRL-----VLTFLWN 842
Query: 2065 NNEFQL-QLSPKTFASKTYGLCGICDENGA---NDFMLRDGTVTTDWKTLVQEWTVQRPG 2120
+ L +L PK +A++T GLCG D NG N+F + +T +Q+ + P
Sbjct: 843 GEDSALLELDPK-YANQTCGLCG--DFNGLPAFNEFYAHNARLTPLQFGNLQK--LDGPT 897
Query: 2121 QTCQ---PILEEQCLVPDSSHCQVLLLPLFAECHKVLAPATFYAICQQDSCHQEQV-CEV 2176
+ C P+ C + + LL P FAECH ++ + A C QD C C
Sbjct: 898 EQCPDPLPLPAGNCTDEEGICHRTLLGPAFAECHALVDSTAYLAACAQDLCRCPTCPCAT 957
Query: 2177 IASYAHLC-RTNGVCVDWRTPDFCAMSCPPSLVYNHCEHGCPRHCDG--NVSSCGDHPSE 2233
Y+ C G +WR P+ C +CP ++ + C C C C DH +
Sbjct: 958 FVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTCSNPQRAQLCEDHCVD 1017
Query: 2234 GCFCPPDKVMLEGSCVPEEACTQCIGEDGVQH--QFLEAWVPDHQPCQICTCLSGRKVNC 2291
GCFCPP + + C +G+ H + + C CTC SG C
Sbjct: 1018 GCFCPPGRSCTVLDDITHSGCLP-LGQCPCTHGGRTYSPGTSFNTTCSSCTC-SGGLWQC 1075
Query: 2292 TTQPCP 2297
PCP
Sbjct: 1076 QDLPCP 1081
Score = 112 bits (281), Expect = 4e-24
Identities = 132/530 (24%), Positives = 199/530 (37%), Gaps = 58/530 (10%)
Query: 1877 RICMDE--DGNEKRPGDVWTLPDQCHTVTCQPDGQTLLKSHRVNCDRGLRPSCPNSQSPV 1934
++C D DG PG T+ D C P GQ C G R P +
Sbjct: 1009 QLCEDHCVDGCFCPPGRSCTVLDDITHSGCLPLGQC-------PCTHGGRTYSPGTSFNT 1061
Query: 1935 KVEE-TC-GCRWTC---PC--VCTGSSTRHIVTFDGQNFKLTGSCSYVLFQN-KEQDLEV 1986
TC G W C PC C+ HI T+D + + L G CSYVL + + V
Sbjct: 1062 TCSSCTCSGGLWQCQDLPCPGTCSVQGGAHISTYDEKLYDLHGDCSYVLSKKCADSSFTV 1121
Query: 1987 ILHNGACSPGARQGCMKSIEVKHSA--LSVELHSDMEVTVNGRLVSVPYVGGNMEVNVYG 2044
+ C + C+K++ + ++ + +D V +N +P N+ +
Sbjct: 1122 LAELRKCGLTDNENCLKAVTLSLDGGDTAIRVQADGGVFLNSIYTQLPLSAANITLFTPS 1181
Query: 2045 AIMHEVRFN-HLGHIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTV 2103
+ V+ L + P F ++L P + GLCG ++N A+DF G V
Sbjct: 1182 SFFIVVQTGLGLQLLVQLVPLMQVF-VRLDP-AHQGQMCGLCGNFNQNQADDFTALSGVV 1239
Query: 2104 TTDWKTLVQEWTVQRPGQTCQPILEEQCLVPDSSH------CQVLLLP--LFAECHKVLA 2155
W Q + E+ C + + C L P F+ CH ++
Sbjct: 1240 EATGAAFANTWKAQAACANARNSFEDPCSLSVENENYARHWCSRLTDPNSAFSRCHSIIN 1299
Query: 2156 PATFYAICQQDSCHQEQ----VCEVIASYAHLCRTNGVCV-DWRTPDFCA---MSCPPSL 2207
P F++ C D+C+ E+ +C ++SY H C GV + DWR C +CP S
Sbjct: 1300 PKPFHSNCMFDTCNCERSEDCLCAALSSYVHACAAKGVQLSDWR-DGVCTKYMQNCPKSQ 1358
Query: 2208 VYNHCEHGCPRHCDG-----NVSSCGDHPSEGCFCPPDKVMLE-GSCVPEEACTQCIGED 2261
Y + C C G S P +GC CP + + G+CVP + C C
Sbjct: 1359 RYAYVVDACQPTCRGLSEADVTCSVSFVPVDGCTCPAGTFLNDAGACVPAQEC-PCYAHG 1417
Query: 2262 GVQHQFLEAWVPDHQPCQICTCLSGRKVNCTTQPCPTAKAPTCGLCEVARLRQNADQCCP 2321
V L H +C+C +G K++C K+ C V N+ P
Sbjct: 1418 TV----LAPGEVVHDEGAVCSC-TGGKLSCL--GASLQKSTGCAAPMVYLDCSNSSAGTP 1470
Query: 2322 EYECVCDPVSCDLPPV-PHCERG--LQPTLTNPGE--CRPNFTCACRKEE 2366
EC+ + D+ HC G P L + G C C C E
Sbjct: 1471 GAECLRSCHTLDVGCFSTHCVSGCVCPPGLVSDGSGGCIAEEDCPCVHNE 1520
Score = 110 bits (275), Expect = 2e-23
Identities = 102/385 (26%), Positives = 150/385 (38%), Gaps = 41/385 (10%)
Query: 22 CAEGTRGRSSTARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRSFSIIGDFQN--- 78
C G CS++G +TFDG+ Y+F G C+Y+L R ++ N
Sbjct: 5397 CVGGRGITPGAGICSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYLDNHYC 5456
Query: 79 ---GKRVSLSVYLGEFFDIH-----LFVNGTVTQGDQR---------VSMPYASKGLYLE 121
+ + IH + + T+ G + VS ++ G+ +
Sbjct: 5457 TASATAAAAAARCPRALSIHYKSMDIVLTVTMVHGKEEGLILFDQIPVSSGFSKNGVLVS 5516
Query: 122 T-EAGYYKLSGEAYGFVARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTL 180
++ A G +G L + N T G CG DD + ++GT
Sbjct: 5517 VLGTTTMRVDIPALGVSVTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTT 5576
Query: 181 TSDPYDFANSWALSSGEQ---WCERASPPSSS--CNISSGEMQKGLWEQ--CQLLKSTSV 233
+ D A +W + + W +PP++S +SS Q C L+ S V
Sbjct: 5577 AASCKDMAKTWLVPDSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQPLCDLMLS-QV 5635
Query: 234 FARCHPLVDPEPFVALCEKTLCECAGGLECACPALLEYARTCAQEGMVLYGWTDHSA--C 291
FA CH LV P PF C C G LE C +L YA C G V W + C
Sbjct: 5636 FAECHNLVPPGPFFNACISD--HCRGRLEVPCQSLEAYAELCRARG-VCSDWRGATGGLC 5692
Query: 292 SPVCPAGMEYRQCVSPCARTCQSLHINEMCQERCVDGCSCPEGQLL---DEGLCVESTEC 348
CP Y+ C TC S + + E +GC CPE Q+L G+CV++ C
Sbjct: 5693 DLTCPPTKVYKPCGPIQPATCNSRNQSPQL-EGMAEGCFCPEDQILFNAHMGICVQA--C 5749
Query: 349 PCV-HSGKRYPPGTSLSRDCNTCIC 372
PCV G PG +C +C+C
Sbjct: 5750 PCVGPDGFPKFPGERWVSNCQSCVC 5774
Score = 109 bits (273), Expect = 3e-23
Identities = 102/371 (27%), Positives = 161/371 (43%), Gaps = 41/371 (11%)
Query: 1949 VCTGSSTRHIVTFDGQNFKLTGSCSYVLFQN---KEQDLEVILHNGACSPGARQGCMKSI 2005
VC+ + H TFDG F+ G C+YV ++ +D + L S + + +
Sbjct: 80 VCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRR---SQESAAPTLSRV 136
Query: 2006 EVKHSALSVELHSDMEVTVNGRLVSVPYVGGNMEVNVYGAIMH-EVRFNHLGHIFTFTPQ 2064
+K + ++L V VNG V +P+ + + + E R LG + +
Sbjct: 137 LMKVDGVVIQLTKG-SVLVNGHPVLLPFSQSGVLIQQSSSYTKVEAR---LGLVLMWN-H 191
Query: 2065 NNEFQLQLSPKTFASKTYGLCGICDENG---ANDFMLRDGTVTTDWKTLVQEWTVQRPGQ 2121
++ L+L K +A+KT GLCG D NG ++ + + +T +Q+ + P +
Sbjct: 192 DDSLLLELDTK-YANKTCGLCG--DFNGMPVVSELLSHNTKLTPMEFGNLQK--MDDPTE 246
Query: 2122 TCQPILEE---QCLVPDSSHCQVLLLPLFAECHKVLAPATFYAICQQDSCHQEQ------ 2172
CQ + E C ++L LF+ C ++ ++ C+QD C E
Sbjct: 247 QCQDPVPEPPRNCSTGFGICEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDLLSC 306
Query: 2173 VCEVIASYAHLC-RTNGVCVDWRTPDFCAMSCPPSLVYNHCEHGCPRHCDGNVSS--CGD 2229
VC +A Y+ C G+ DWR PDFC CP ++ Y+ C C C S C D
Sbjct: 307 VCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCSNQEHSRACED 366
Query: 2230 HPSEGCFCPPDKVM---LEGSCVPEEACTQCIGEDGVQHQFLEAWVPDHQPCQICTCLSG 2286
H GCFCP V+ + CVP C C+ +G + + D C CTC SG
Sbjct: 367 HCVAGCFCPEGTVLDDIGQTGCVPVSKCA-CV-YNGAAYAPGATYSTD---CTNCTC-SG 420
Query: 2287 RKVNCTTQPCP 2297
+ +C PCP
Sbjct: 421 GRWSCQEVPCP 431
Score = 105 bits (262), Expect = 6e-22
Identities = 85/302 (28%), Positives = 127/302 (42%), Gaps = 28/302 (9%)
Query: 132 EAYGFVARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSW 191
E +G D + + L Y + CGLCGNF+ A +DF T+ ++ D +F NSW
Sbjct: 1689 ETHGMAVSWDRKTSVFIRLHQDYKGRVCGLCGNFDDNAINDFATRSRSVVGDALEFGNSW 1748
Query: 192 ALSSGEQWCERASPPSSSCNISSGEMQKGLWEQCQLLKSTSVFARCHPLVDPEPFVALCE 251
LS C A P C ++ + +QC +L + FA C VD + C
Sbjct: 1749 KLSPS---CPDALAPKDPCT-ANPFRKSWAQKQCSILHGPT-FAACRSQVDSTKYYEACV 1803
Query: 252 KTLCEC--AGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVC----PAG---MEYR 302
C C G EC C A+ YA+ C G+ + W C C P G Y+
Sbjct: 1804 NDACACDSGGDCECFCTAVAAYAQACHDAGLCV-SWRTPDTCPLFCDFYNPHGGCEWHYQ 1862
Query: 303 QCVSPCARTCQSLHINEMCQERCVDGC--SCPEGQLL---DEGLCVESTECPCV-HSGKR 356
C +PC +TC++ + + ++GC CP Q D+ CV +C C G
Sbjct: 1863 PCGAPCLKTCRNPSGHCLVDLPGLEGCYPKCPPSQPFFNEDQMKCV--AQCGCYDKDGNY 1920
Query: 357 YPPGTSL--SRDCNTCICRNSQWICSNEECPGECLVTGQSHFKSF-DNRYFTFSGICQYL 413
Y G + + +C +C C S C++ C T + S+ D Y T G+ L
Sbjct: 1921 YDVGARVPTAENCQSCNCTPSGIQCAHS--LEACTCTYEDRTYSYQDVIYNTTDGLGACL 1978
Query: 414 LA 415
+A
Sbjct: 1979 IA 1980
Score = 104 bits (260), Expect = 1e-21
Identities = 104/410 (25%), Positives = 147/410 (35%), Gaps = 71/410 (17%)
Query: 1939 TCGCR---WTCP---CV--CTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKEQD------L 1984
TC CR W C C+ C H +TFDG + GSC Y+L Q+ D
Sbjct: 1535 TCTCRNRRWECSHRLCLGTCVAYGDGHFITFDGDRYSFEGSCEYILAQDYCGDNTTHGTF 1594
Query: 1985 EVILHNGACSPGARQGCMKSIEVKHSALSVELHSDMEVTVNG---RLVSVPYVGGNMEVN 2041
++ N C C K+I++ + S + N R SV + +
Sbjct: 1595 RIVTENIPCGTTGTT-CSKAIKLFVEVRTAPAVSTPDPAANEPAPREASVGFRQRLPPLQ 1653
Query: 2042 VYGAIMHEVRFNHLGH--------------IFTFTPQNNEFQLQLSPKT---------FA 2078
Y I+ E F + IF + + + KT +
Sbjct: 1654 SYELILQEGTFKAVARGPGGDPPYKIRYMGIFLVI-ETHGMAVSWDRKTSVFIRLHQDYK 1712
Query: 2079 SKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTVQRPGQTCQPIL--EEQCLVPD- 2135
+ GLCG D+N NDF R +V D W + +C L ++ C
Sbjct: 1713 GRVCGLCGNFDDNAINDFATRSRSVVGDALEFGNSWKLS---PSCPDALAPKDPCTANPF 1769
Query: 2136 -----SSHCQVLLLPLFAECHKVLAPATFYAICQQDSC------HQEQVCEVIASYAHLC 2184
C +L P FA C + +Y C D+C E C +A+YA C
Sbjct: 1770 RKSWAQKQCSILHGPTFAACRSQVDSTKYYEACVNDACACDSGGDCECFCTAVAAYAQAC 1829
Query: 2185 RTNGVCVDWRTPDFCAMSCP-------PSLVYNHCEHGCPRHCDGNVSSC-GDHPS-EGC 2235
G+CV WRTPD C + C Y C C + C C D P EGC
Sbjct: 1830 HDAGLCVSWRTPDTCPLFCDFYNPHGGCEWHYQPCGAPCLKTCRNPSGHCLVDLPGLEGC 1889
Query: 2236 F--CPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWVPDHQPCQICTC 2283
+ CPP + + A C +DG + + A VP + CQ C C
Sbjct: 1890 YPKCPPSQPFFNEDQMKCVAQCGCYDKDG-NYYDVGARVPTAENCQSCNC 1938
Score = 98.2 bits (243), Expect = 1e-19
Identities = 111/437 (25%), Positives = 162/437 (37%), Gaps = 69/437 (15%)
Query: 867 CSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPGTFRILVGNKGC------SHPSVK 920
CS G +HY TFDG Y F G C YVL+++ + G + + N C + + +
Sbjct: 5410 CSMWGGSHYSTFDGTSYTFRGNCTYVLMRE-IHARFGNLSLYLDNHYCTASATAAAAAAR 5468
Query: 921 CKKRVTILVEGGEIELFDGEVNVKRPMKDETHFEVVESG----RYIILLLGKALSVVWDR 976
C + ++I + +I L V+ K V SG ++ +LG V
Sbjct: 5469 CPRALSIHYKSMDIVLTVTMVHGKEEGLILFDQIPVSSGFSKNGVLVSVLGTTTMRVDIP 5528
Query: 977 HLSISVVLK-QTYQEKVC---------GLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWK 1026
L +SV Q +Q ++ G CG Q +D + D +W
Sbjct: 5529 ALGVSVTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTAASCKDMAKTWL 5588
Query: 1027 VSSQCADTRKVPLDSSPATCHNNIMKQTMVDSS------CRILTSDVFQDCNKLVDPEPY 1080
V D P + P + T + C ++ S VF +C+ LV P P+
Sbjct: 5589 VPDSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQPLCDLMLSQVFAECHNLVPPGPF 5648
Query: 1081 LDVCIYDTCSCESIGDCACFCDTIAAYAHVCAQHGKVVTWRTAT--LCPQSCEERNLREN 1138
+ CI D C G C ++ AYA +C G WR AT LC +C +
Sbjct: 5649 FNACISDHCR----GRLEVPCQSLEAYAELCRARGVCSDWRGATGGLCDLTCPPTKV--- 5701
Query: 1139 GYECEWRYNSCAPACQVTCQHPEPLACPVQCVEGCHAHCPPGKIL-DELLQTCVDPEDCP 1197
Y C P TC EGC CP +IL + + CV + CP
Sbjct: 5702 -------YKPCGPIQPATCNSRNQSPQLEGMAEGC--FCPEDQILFNAHMGICV--QACP 5750
Query: 1198 VCEVAGRRFASGKKVTLNPSDPEHCQICHCDVVN-------LTCEA------CQEPGGLV 1244
G G++ N CQ C CD + L C+A C PG +
Sbjct: 5751 CVGPDGFPKFPGERWVSN------CQSCVCDEGSVSVQCKPLPCDAQGQPPPCNRPGFVT 5804
Query: 1245 V--PPTDAPVSPTTLYV 1259
V P + P P T+ V
Sbjct: 5805 VTRPRAENPCCPETVCV 5821
Score = 50.8 bits (120), Expect = 2e-05
Identities = 56/228 (24%), Positives = 89/228 (39%), Gaps = 20/228 (8%)
Query: 1939 TC-GCRWTC---PC--VCTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKEQD-LEVILHNG 1991
TC G RW+C PC C+ H TFDG+ + + G CSYVL + + V+
Sbjct: 417 TCSGGRWSCQEVPCPGTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSAFTVLAELR 476
Query: 1992 ACSPGARQGCMKSIEVKHSALS--VELHSDMEVTVNGRLVSVPYVGGNMEVNVYGAIMHE 2049
C + C+KS+ + V + + EV +N +P N+ + +
Sbjct: 477 RCGLTDSETCLKSVTLSLDGAQTVVVIKASGEVFLNQIYTQLPISAANVTI-FRPSTFFI 535
Query: 2050 VRFNHLG-HIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWK 2108
+ LG + + +QL+PK +T GLCG + A+DF G V
Sbjct: 536 IAQTSLGLQLNLQLVPTMQLFMQLAPK-LRGQTCGLCGNFNSIQADDFRTLSGVVEATAA 594
Query: 2109 TLVQEWTVQRPGQTCQPILEEQCLVP--------DSSHCQVLLLPLFA 2148
+ Q + E+ C + S C+ L+L L A
Sbjct: 595 AFFNTFKTQAACPNIRNSFEDPCSLSVENAPRMGAPSACRTLVLALAA 642
Score = 42.0 bits (97), Expect = 0.009
Identities = 56/230 (24%), Positives = 84/230 (36%), Gaps = 57/230 (24%)
Query: 2542 IQQRNVSCPQLEVPV----CPSGFQLSCKTSACCPSCRCERMEACMLNGTVIGPGKTVMI 2597
+ + +V+C VPV CP+G L+ AC P+ C C +GTV+ PG+ V+
Sbjct: 1374 LSEADVTCSVSFVPVDGCTCPAGTFLN-DAGACVPAQECP----CYAHGTVLAPGE-VVH 1427
Query: 2598 DVCTTCRCMVQVGVISGFKLEC-----RKTTCNPCPLGYKEENNT------GECCGRC-- 2644
D C C +G KL C +K+T P+ Y + +N+ EC C
Sbjct: 1428 DEGAVCSC-------TGGKLSCLGASLQKSTGCAAPMVYLDCSNSSAGTPGAECLRSCHT 1480
Query: 2645 ---------------LPTACTIQLRGGQI-----------MTLKRDETLQDGCDTHFCKV 2678
P GG I T K ET++ C+T C+
Sbjct: 1481 LDVGCFSTHCVSGCVCPPGLVSDGSGGCIAEEDCPCVHNEATYKPGETIRVDCNTCTCR- 1539
Query: 2679 NERGEYFWEKRVTGCPPFDEHKCLAEGGKIMKIPGTCCDTCEEPECNDIT 2728
N R E + C + + + G G+C + C D T
Sbjct: 1540 NRRWECSHRLCLGTCVAYGDGHFITFDGDRYSFEGSCEYILAQDYCGDNT 1589
Score = 40.4 bits (93), Expect = 0.025
Identities = 39/142 (27%), Positives = 55/142 (38%), Gaps = 22/142 (15%)
Query: 785 GLECTKTCQNYDLECM-SMGCVSGCL--CPPGM-VRHENRCVALERCPCFHQ-GKEYAPG 839
G C KTC+N C+ + + GC CPP +E++ + +C C+ + G Y G
Sbjct: 1865 GAPCLKTCRNPSGHCLVDLPGLEGCYPKCPPSQPFFNEDQMKCVAQCGCYDKDGNYYDVG 1924
Query: 840 ETVKI--GCNTCVCRDRKWNCTDHVCDATCSTIGMAH------YLTFDGLKYLFPGECQY 891
V C +C C C + TC+ + Y T DGL G C
Sbjct: 1925 ARVPTAENCQSCNCTPSGIQCAHSLEACTCTYEDRTYSYQDVIYNTTDGL-----GACLI 1979
Query: 892 VLVQDYCGSNPGTFRILVGNKG 913
+ CGSN R V G
Sbjct: 1980 AI----CGSNGTIIRKAVACPG 1997
Score = 39.3 bits (90), Expect = 0.055
Identities = 65/280 (23%), Positives = 96/280 (34%), Gaps = 57/280 (20%)
Query: 2318 QCCPEYECVC---DPVSCDLPPVPHCER------GLQPTLTNPGECRPNFTCACRKEECK 2368
+ C + C C D +SC + R GL P C + EC+
Sbjct: 289 EACRQDLCFCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECR 348
Query: 2369 RVSPPSCPPHRLPTLRKTQCCDEYECACNCVNSTVSCPLGYLASTATNDCGCTTTTCLPD 2428
+C ++ C+++ C C CP G T +D G T +
Sbjct: 349 SPCADTCSNQE-----HSRACEDH-CVAGCF-----CPEG----TVLDDIGQTGCVPVSK 393
Query: 2429 KVCVHRSTIYPVGQFWEEGCDVCTCTDMEDAVMGLRVAQCSQKPCEDSCR---------- 2478
CV+ Y G + C CTC+ G R + C + PC +C
Sbjct: 394 CACVYNGAAYAPGATYSTDCTNCTCS-------GGRWS-CQEVPCPGTCSVLGGAHFSTF 445
Query: 2479 SGFTYVLHEGEC----CGRCLPSACEVVTGSPR---GDSQSSWKSVGSQWASPENPCLIN 2531
G Y +H G+C C SA V+ R DS++ KSV + +I
Sbjct: 446 DGKQYTVH-GDCSYVLTKPCDSSAFTVLAELRRCGLTDSETCLKSVTLSLDGAQTVVVI- 503
Query: 2532 ECVRVKEEVFIQQRNVSCPQLEVPVC---PSGFQLSCKTS 2568
+ EVF+ Q P V PS F + +TS
Sbjct: 504 ---KASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTS 540
Score = 38.1 bits (87), Expect = 0.12
Identities = 25/73 (34%), Positives = 31/73 (42%), Gaps = 16/73 (21%)
Query: 2557 CPSGFQLS-CKTSACCPSCRCERMEACMLNGTVIGPGKTVMIDVCTTCRCMVQVGVISGF 2615
CP G L + C P +C AC+ NG PG T D CT C C SG
Sbjct: 374 CPEGTVLDDIGQTGCVPVSKC----ACVYNGAAYAPGATYSTD-CTNCTC-------SGG 421
Query: 2616 KLECRKTTCNPCP 2628
+ C++ PCP
Sbjct: 422 RWSCQEV---PCP 431
Score = 36.2 bits (82), Expect = 0.47
Identities = 32/124 (25%), Positives = 45/124 (36%), Gaps = 21/124 (16%)
Query: 2363 RKEECKRVSPPSCPPHRLPTLRKTQCCDEYE-------CACNCVNSTVSCPLGYLASTAT 2415
R C + P +CP + + C D C +CV+ CP G + T
Sbjct: 973 RNWRCPELCPRTCPLNMQHQECGSPCTDTCSNPQRAQLCEDHCVDGCF-CPPGR-SCTVL 1030
Query: 2416 NDCGCTTTTCLP--DKVCVHRSTIYPVGQFWEEGCDVCTCTDMEDAVMGLRVAQCSQKPC 2473
+D T + CLP C H Y G + C CTC+ + QC PC
Sbjct: 1031 DDI--THSGCLPLGQCPCTHGGRTYSPGTSFNTTCSSCTCSG--------GLWQCQDLPC 1080
Query: 2474 EDSC 2477
+C
Sbjct: 1081 PGTC 1084
Score = 33.5 bits (75), Expect = 3.0
Identities = 23/81 (28%), Positives = 34/81 (41%), Gaps = 15/81 (18%)
Query: 1879 CMDEDGNEKRPGDVWTLPDQCHTVTCQPDGQTLLKSHRVNCD-RGLRPSC---------- 1927
C+ DG K PG+ W C + C +G ++ + CD +G P C
Sbjct: 5751 CVGPDGFPKFPGERWV--SNCQSCVCD-EGSVSVQCKPLPCDAQGQPPPCNRPGFVTVTR 5807
Query: 1928 PNSQSPVKVEETCGCR-WTCP 1947
P +++P E C C TCP
Sbjct: 5808 PRAENPCCPETVCVCNTTTCP 5828
Score = 32.0 bits (71), Expect = 8.8
Identities = 38/138 (27%), Positives = 53/138 (38%), Gaps = 18/138 (13%)
Query: 2543 QQRNVSCPQLEVPVCPSGFQLSCKTSACCPSC----RCERMEACMLNGTVIGPGK--TVM 2596
Q RN CP+L CP Q S C +C R + E ++G PG+ TV+
Sbjct: 971 QPRNWRCPELCPRTCPLNMQHQECGSPCTDTCSNPQRAQLCEDHCVDGCFCPPGRSCTVL 1030
Query: 2597 IDVC-TTCRCMVQVGVISGFKL----ECRKTTCNPCPLGYKEENNTGECCGRCLPTACTI 2651
D+ + C + Q G + TTC+ C +C P C++
Sbjct: 1031 DDITHSGCLPLGQCPCTHGGRTYSPGTSFNTTCSSCTC----SGGLWQCQDLPCPGTCSV 1086
Query: 2652 QLRGGQIMTLKRDETLQD 2669
Q G I T DE L D
Sbjct: 1087 Q-GGAHISTY--DEKLYD 1101
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 753 bits (1945), Expect = 0.0
Identities = 428/1271 (33%), Positives = 613/1271 (48%), Gaps = 70/1271 (5%)
Query: 4 ARFAGVLLALALILPGTLCAEGTRGRSSTARCSLFGSDFVNTFDGSMYSFAGYCSYLLAG 63
AR A V LAL+L L EG CS +G+ TFDG ++ F G C Y A
Sbjct: 6 ARLAAVCLALSLAGGSELQTEGRTRNHGHNVCSTWGNFHYKTFDGDVFRFPGLCDYNFAS 65
Query: 64 GCQ--KRSFSI---IGDFQNGKRVSLSVYLGEFFD--IHLFVNGTVTQGDQRVSMPYASK 116
C+ + F++ G Q + L D I+L + V G VS P+ S
Sbjct: 66 DCRGSYKEFAVHLKRGPGQAEAPAGVESILLTIKDDTIYLTRHLAVLNG-AVVSTPHYSP 124
Query: 117 GLYLETEAGYYKLSGEAYGFVARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQ 176
GL +E Y K+ A G + + L ++ N TCGLCG++N
Sbjct: 125 GLLIEKSDAYTKVYSRA-GLTLMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLS 183
Query: 177 EGTLTSDPYDFANSWALSSGEQWCERASPPSSSCNISSGEMQKGLWEQCQLLKSTSVFAR 236
+G L S P +F N ++ + CE P S E + +C+ L + FA
Sbjct: 184 DGVLFS-PLEFGNMQKINQPDVVCE--DPEEEVAPASCSEHR----AECERLLTAEAFAD 236
Query: 237 CHPLVDPEPFVALCEKTLCECAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCP 296
C LV EP++ C++ C C GG C C + E++R C+ G W + C CP
Sbjct: 237 CQDLVPLEPYLRACQQDRCRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATLCPKTCP 296
Query: 297 AGMEYRQCVSPCARTCQSLHINEMCQERCVDGCSCPEGQLLD---EGLCVESTECPCVHS 353
+ Y + SPC TC L ++ +C+E +DGC CPEG + D + CV ++C C
Sbjct: 297 GNLVYLESGSPCMDTCSHLEVSSLCEEHRMDGCFCPEGTVYDDIGDSGCVPVSQCHCRLH 356
Query: 354 GKRYPPGTSLSRDCNTCICRNSQWICSNEECPGECLVTGQSHFKSFDNRYFTFSGICQYL 413
G Y PG ++ DC C+C +W+C + CPG C + G SH +FD + +TF G C Y+
Sbjct: 357 GHLYTPGQEITNDCEQCVCNAGRWVCKDLPCPGTCALEGGSHITTFDGKTYTFHGDCYYV 416
Query: 414 LARDCQDHSFSIVIETVQCADDRDAVCTRSVTVRLPGLHNSLVKLKHGAGVAMDGQDVQL 473
LA+ + S++++ E C C ++V V L ++V K V ++ V L
Sbjct: 417 LAKGDHNDSYALLGELAPCGSTDKQTCLKTV-VLLADKKKNVVVFKSDGSVLLNELQVNL 475
Query: 474 PLLKGDLRI--QHTVTASVRLSYGEDLQMDWDGRGRLLVKLSPVYAGKTCGLCGNYNGNQ 531
P + + + V ++ G LQ+ +L V L G+ GLCGN+NG +
Sbjct: 476 PHVTASFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQGLCGNFNGLE 535
Query: 532 GDDFLTPSGLAEPRVEDFGNAWKLHGDCQDLQKQHSDPCALNPRMTRFSEEACAVL--TS 589
GDDF T SGL E F N WK C D DPC+LN ++E C++L T
Sbjct: 536 GDDFKTASGLVEATGAGFANTWKAQSSCHDKLDWLDDPCSLNIESANYAEHWCSLLKKTE 595
Query: 590 PTFEACHRAVSPLPYLRNCRYDVCSCSDGRECLCGALASYAAACAGRGVRV-AWREP--G 646
F CH AV P Y + C+YD C+C + +CLC AL+SYA AC +GV + WRE
Sbjct: 596 TPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACTAKGVMLWGWREHVCN 655
Query: 647 RCELNCPKGQVYLQCGTPCNLTCRSLSYPDEECNE--ACLEGCFCPPGLYMDERGDCVPK 704
+ +CP QV+L T C TCRSLS D C E A ++GC CP ++DE+G CVP
Sbjct: 656 KDVGSCPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPL 715
Query: 705 AQCPCYYDGEIFQPEDIFSDHHTMCYCEDGFMHCTMSGVPGSLLPDAVLSSPLSHRSKRS 764
A+C CY+ G + D+ C C DG +HC + G
Sbjct: 716 AKCSCYHRGLYLEAGDVVVRQEERCVCRDGRLHCRQIRLIGQ------------------ 757
Query: 765 LSCRPPMVKLVCPADNLRAEGLECTKTCQNYDLECMSMGCVSGCLCPPGMVRH-ENRCVA 823
SC P + + C A +CQ CVSGC+CP G++ CV
Sbjct: 758 -SCTAPKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPDGLMDDGRGGCVV 816
Query: 824 LERCPCFHQGKEYAPGETVKIGCNTCVCRDRKWNCTDHVCDATCSTIGMAHYLTFDGLKY 883
+ CPC H Y+ G +K+ CNTC C+ +W CT VC TCS G HY+TFDG Y
Sbjct: 817 EKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAVCHGTCSIYGSGHYITFDGKYY 876
Query: 884 LFPGECQYVLVQDYCGSNP--GTFRILVGNKGCSHPSVKCKKRVTILVEGGEIELFD-GE 940
F G C YV VQDYCG N G+F I+ N C V C K + I + E++L D
Sbjct: 877 DFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHR 936
Query: 941 VNVKRPMKDETHFEVVESGRYIILLLGKALSVVWDRHLSISVVLKQTYQEKVCGLCGNFD 1000
V ++R + E G+Y+++ + V+WD+ ++ + L +Y+ VCGLCGNFD
Sbjct: 937 VVIQRDEGHHVAYTTREVGQYLVVESSTGIIVIWDKRTTVFIKLAPSYKGTVCGLCGNFD 996
Query: 1001 GIQNNDLTSSNLQVEEDPVDFGNSWKVSSQCADTRKVPLDSSPATCHNNIMKQTMVDSSC 1060
NND T+ + V +DFGNSWK + C D + ++P C N +++ + C
Sbjct: 997 HRSNNDFTTRDHMVVSSELDFGNSWKEAPTCPD-----VSTNPEPCSLNPHRRSWAEKQC 1051
Query: 1061 RILTSDVFQDCNKLVDPEPYLDVCIYDTCSCESIGDCACFCDTIAAYAHVCAQHGKVVTW 1120
IL S VF C+ VDP+P+ + C++D+CSC++ GDC CFC +A+YA C + G V W
Sbjct: 1052 SILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACVFW 1111
Query: 1121 RTATLCPQSCEERNLRENGYECEWRYNSCAPACQVTCQHPEPL--ACPVQCVEGCHAHCP 1178
RT LCP C+ N +ECEW Y C TC+ + V +EGC+ CP
Sbjct: 1112 RTPDLCPIFCDYYN---PPHECEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCP 1168
Query: 1179 PGK-ILDELLQTCVDPEDCPVCEVAGRRFASGKKVTLNPSDPEHCQICHCDVVNLTCEAC 1237
+ I +E L+ CV + C C V + G V P++ E C+ C C N + C
Sbjct: 1169 KDRPIYEEDLKKCVTADKCG-CYVEDTHYPPGASV---PTE-ETCKSCVC--TNSSQVVC 1221
Query: 1238 QEPGGLVVPPT 1248
+ G ++ T
Sbjct: 1222 RPEEGKILNQT 1232
Score = 252 bits (643), Expect = 4e-66
Identities = 213/807 (26%), Positives = 315/807 (39%), Gaps = 138/807 (17%)
Query: 1879 CMDEDGNEKRPGDVWTLPDQCHTVTCQPDGQTLLKSHRVNCDRGLRPSCPNSQSPVKVEE 1938
C D D ++ + W L D C TC+ + + +V C+ P+C N PV+VE+
Sbjct: 4412 CPDFDP-PRQENETWWLCD-CFMATCKYNNTVEIV--KVECEPPPMPTCSNGLQPVRVED 4467
Query: 1939 TCGC--RWTCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKEQDLE---VILHNGAC 1993
GC W C C CTG H VTFDG + G+C+YVL + ++ V + N C
Sbjct: 4468 PDGCCWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHC 4527
Query: 1994 SPGARQGCMKSIEVKHSALSVELHS------DMEVTVNGRLVSVPYVGGNMEVNVYGAIM 2047
P + C +++ V+H V + + ++V VN + V++PY +EV G I
Sbjct: 4528 DPNDKVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSG-IN 4586
Query: 2048 HEVRFNHLGHIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDW 2107
+ V LG + ++ F ++L F + T G CG C ++D +L G + ++
Sbjct: 4587 YVVDIPELGVLVSY--NGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNC 4644
Query: 2108 KTLVQEWTVQRPGQTCQPILEEQCLVP-----------------DSSHCQVLLLPLFAEC 2150
+ +W V P + P P S CQ++ LFA+C
Sbjct: 4645 EAAADQWLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQC 4704
Query: 2151 HKVLAPATFYAICQQDSCH---QEQVCEVIASYAHLCRTNGVCVDWR--TPDFCAMSCPP 2205
H ++ P +Y C DSC C + +YA LC +C+DWR T C + CP
Sbjct: 4705 HALVPPQHYYDACVFDSCFMPGSSLECASLQAYAALCAQQNICLDWRNHTHGACLVECPS 4764
Query: 2206 SLVYNHCEHGCPRHCDGNVSSCGDHP-SEGCFCPPDKV-MLEGSCVPEEACTQCIGEDGV 2263
Y C C + S + EGCFCP + G V + C C+G D V
Sbjct: 4765 HREYQACGPAEEPTCKSSSSQQNNTVLVEGCFCPEGTMNYAPGFDVCVKTC-GCVGPDNV 4823
Query: 2264 QHQFLEAWVPDHQPCQICTCLSGRKVNCTTQPCPTAKAPTCGLCEVARLRQNADQCCPEY 2323
+F E + D C+ C CL G
Sbjct: 4824 PREFGEHFEFD---CKNCVCLEGGS----------------------------------- 4845
Query: 2324 ECVCDPVSCDLPPVPHC-ERGLQ-PTLTNPGECRPNFT-CACRKEECKRVSPPSCPPHRL 2380
+C P C PV HC E G T NP + N T C C CK PS
Sbjct: 4846 GIICQPKRCSQKPVTHCVEDGTYLATEVNPADTCCNITVCKCNTSLCK--EKPSV----- 4898
Query: 2381 PTLRKTQCCDEYECACNCVNSTVSCPLGY-LASTATNDCGCTTTTCLPDKVCVHRSTIY- 2438
CPLG+ + S C C VCVH + Y
Sbjct: 4899 ------------------------CPLGFEVKSKMVPGRCCPFYWCESKGVCVHGNAEYQ 4934
Query: 2439 PVGQFWEEGCDVCTCTDMEDAVMGLRVAQCSQKPCEDSCRSGFTYVLHEGECCGRCLPSA 2498
P + C C CTD D L V C+ PC SC GF + GECC +C +
Sbjct: 4935 PGSPVYSSKCQDCVCTDKVDNNTLLNVIACTHVPCNTSCSPGFELMEAPGECCKKCEQTH 4994
Query: 2499 CEVVTGSPRGDSQSSWKSVGSQWASPENPCLINECVRVKEEVFIQQRNVSCPQLEVPVCP 2558
C + R D+Q G + P+N C CV++ ++ N++CP + +C
Sbjct: 4995 CII----KRPDNQHVILKPGDFKSDPKNNCTFFSCVKIHNQLISSVSNITCPNFDASICI 5050
Query: 2559 SGFQLSCKTSACCPSC--RCERMEAC-----MLNGTVIGPGKTVMIDVCT-TCRCMVQVG 2610
G ++ + CC +C R E C + G KTV+++ C+ +C V
Sbjct: 5051 PG-SITFMPNGCCKTCTPRNETRVPCSTVPVTTEVSYAGCTKTVLMNHCSGSCGTFVMYS 5109
Query: 2611 VISGFKLECRKTTCNPCPLGYKEENNT 2637
K + +C+ C KEE +
Sbjct: 5110 A----KAQALDHSCSCC----KEEKTS 5128
Score = 131 bits (329), Expect = 1e-29
Identities = 147/591 (24%), Positives = 215/591 (36%), Gaps = 96/591 (16%)
Query: 358 PPGTSLSRDCNTCICRNSQWICSNEECPGECLVTGQSHFKSFDNRYFTFSGICQYLLARD 417
PP + S + C + EC C G H+ +FD Y+++ G C Y+L +
Sbjct: 4451 PPMPTCSNGLQPVRVEDPDGCCWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEE 4510
Query: 418 CQD--HSFSIVIETVQCADDRDAVCTRSVTVRLPGLHNSLVKLKH----GAGVAMDGQDV 471
+F + I+ C + C R++ VR L+K H V ++ Q V
Sbjct: 4511 ISPSVDNFGVYIDNYHCDPNDKVSCPRTLIVR-HETQEVLIKTVHMMPMQVQVQVNRQAV 4569
Query: 472 QLPLLKGDLRIQHTVTASVRLSYGEDLQ-----MDWDGRGRLLVKLSPVYAGKTCGLCGN 526
LP K L + + ++Y D+ + ++G + + T G CG
Sbjct: 4570 ALPYKKYGLEVYQS-----GINYVVDIPELGVLVSYNGLSFSVRLPYHRFGNNTKGQCGT 4624
Query: 527 YNGNQGDDFLTPSGLAEPRVEDFGNAWKLHGDCQDLQKQHSDPCALNPRMT--------- 577
DD + PSG E + W L D HS P +T
Sbjct: 4625 CTNTTSDDCILPSGEIVSNCEAAADQW-LVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTP 4683
Query: 578 ---RFSEEACAVLTSPTFEACHRAVSPLPYLRNCRYDVCSCSDGRECLCGALASYAAACA 634
C ++ F CH V P Y C +D C G C +L +YAA CA
Sbjct: 4684 HKDCTPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSC-FMPGSSLECASLQAYAALCA 4742
Query: 635 GRGVRVAWRE--PGRCELNCPKGQVYLQCGTPCNLTCRSLSYPDEECNEACLEGCFCPPG 692
+ + + WR G C + CP + Y CG TC+S S ++ N +EGCFCP G
Sbjct: 4743 QQNICLDWRNHTHGACLVECPSHREYQACGPAEEPTCKSSS--SQQNNTVLVEGCFCPEG 4800
Query: 693 LYMDERGDCVPKAQCPCYYDGEIFQPEDIFSDHHTM----CYCEDGFMHCTMSGVPGSLL 748
G V C C + P + F +H C C +G SG+
Sbjct: 4801 TMNYAPGFDVCVKTCGCVGPDNV--PRE-FGEHFEFDCKNCVCLEG-----GSGI--ICQ 4850
Query: 749 PDAVLSSPLSHRSKRSLSCRPPMVKLVCPADNLRAEGLECTKTCQNYDL-ECMSMGC-VS 806
P P++H + + V PAD TC N + +C + C
Sbjct: 4851 PKRCSQKPVTH----CVEDGTYLATEVNPAD-----------TCCNITVCKCNTSLCKEK 4895
Query: 807 GCLCPPGMVRHENRCVALERCP---------CFHQGKEYAPGETV-KIGCNTCVCRDRKW 856
+CP G +++ V CP C H EY PG V C CVC D+
Sbjct: 4896 PSVCPLGF-EVKSKMVPGRCCPFYWCESKGVCVHGNAEYQPGSPVYSSKCQDCVCTDKVD 4954
Query: 857 N--------CTDHVCDATCSTIGMAHYLTFDGLKYL-FPGECQYVLVQDYC 898
N CT C+ +CS G + + PGEC Q +C
Sbjct: 4955 NNTLLNVIACTHVPCNTSCS----------PGFELMEAPGECCKKCEQTHC 4995
Score = 122 bits (306), Expect = 5e-27
Identities = 127/453 (28%), Positives = 179/453 (39%), Gaps = 85/453 (18%)
Query: 1898 QCHTVTCQPDGQTLLKSHRVNCDRGLRPSCP--------NSQSPVKVE-ETCGC---RWT 1945
+C + PDG L+ R C + CP +S + +KV+ TC C RW
Sbjct: 795 ECVSGCVCPDG--LMDDGRGGCV--VEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWV 850
Query: 1946 CP-CVCTGS----STRHIVTFDGQNFKLTGSCSYVLFQN------KEQDLEVILHNGACS 1994
C VC G+ + H +TFDG+ + G CSYV Q+ +I N C
Sbjct: 851 CTQAVCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCG 910
Query: 1995 PGARQGCMKSIEVKHSALSVELHSDMEVTVN---GRLVSVPYVGGNMEVNVYGAIMHEVR 2051
C K+I++ ++L V + G V+ EV Y +
Sbjct: 911 TTGVT-CSKAIKIFMGRTELKLEDKHRVVIQRDEGHHVAYT----TREVGQYLVVESST- 964
Query: 2052 FNHLGHIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLV 2111
G I + + F ++L+P ++ GLCG D NDF RD V +
Sbjct: 965 ----GIIVIWDKRTTVF-IKLAP-SYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFG 1018
Query: 2112 QEWTVQRPGQTCQPILE--EQCLVPD------SSHCQVLLLPLFAECHKVLAPATFYAIC 2163
W + TC + E C + C +L +F+ CH + P FY C
Sbjct: 1019 NSW---KEAPTCPDVSTNPEPCSLNPHRRSWAEKQCSILKSSVFSICHSKVDPKPFYEAC 1075
Query: 2164 QQDSCHQ------EQVCEVIASYAHLCRTNGVCVDWRTPDFCAMSCPPSLVYNHCEHGCP 2217
DSC E C +ASYA C G CV WRTPD C + C Y + H C
Sbjct: 1076 VHDSCSCDTGGDCECFCSAVASYAQECTKEGACVFWRTPDLCPIFCD----YYNPPHECE 1131
Query: 2218 RHCD--GNVS--SC----GDHPS------EGCF--CPPDKVMLE---GSCVPEEACTQCI 2258
H + GN S +C G H + EGC+ CP D+ + E CV + C C
Sbjct: 1132 WHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKC-GCY 1190
Query: 2259 GEDGVQHQFLEAWVPDHQPCQICTCLSGRKVNC 2291
ED H A VP + C+ C C + +V C
Sbjct: 1191 VED--THYPPGASVPTEETCKSCVCTNSSQVVC 1221
Score = 120 bits (301), Expect = 2e-26
Identities = 108/452 (23%), Positives = 157/452 (34%), Gaps = 76/452 (16%)
Query: 2374 SCPPHRLPTLRKTQCCDEYEC---ACNCVNSTVSCPLGYLASTATNDCGCTTTTCLPDKV 2430
+C P PT + + C C T++ G+ T CGC +P +
Sbjct: 4770 ACGPAEEPTCKSSSSQQNNTVLVEGCFCPEGTMNYAPGFDVCVKT--CGCVGPDNVPREF 4827
Query: 2431 CVHRSTIYPVGQFWEEGCDVCTCTDMEDAVMGLRVAQCSQKPCEDSCRSGFTYVLHEGEC 2490
G+ +E C C C + ++ + +CSQKP G TY+ E
Sbjct: 4828 ----------GEHFEFDCKNCVCLEGGSGII-CQPKRCSQKPVTHCVEDG-TYLATEVNP 4875
Query: 2491 CGRCLPSACEVVTGSPRGDSQSSWKSVGSQWASPENPCLINECVRVKEEVFIQQRNVSCP 2550
C C I C + N S
Sbjct: 4876 ADTC---------------------------------CNITVC----------KCNTSLC 4892
Query: 2551 QLEVPVCPSGFQLSCKT--SACCPSCRCERMEACMLNGTVIGPGKTVMIDVCTTCRCMVQ 2608
+ + VCP GF++ K CCP CE C+ PG V C C C +
Sbjct: 4893 KEKPSVCPLGFEVKSKMVPGRCCPFYWCESKGVCVHGNAEYQPGSPVYSSKCQDCVCTDK 4952
Query: 2609 VGVISGFK-LECRKTTCNP-CPLGYKEENNTGECCGRCLPTACTIQLRGGQIMTLKRDET 2666
V + + C CN C G++ GECC +C T C I+ Q + LK +
Sbjct: 4953 VDNNTLLNVIACTHVPCNTSCSPGFELMEAPGECCKKCEQTHCIIKRPDNQHVILKPGDF 5012
Query: 2667 LQDGCD--THFCKVNERGEYFWEKRVTGCPPFDEHKCLAEGGKIMKIPGTCCDTCEEPE- 2723
D + T F V + CP FD C+ G I +P CC TC
Sbjct: 5013 KSDPKNNCTFFSCVKIHNQLISSVSNITCPNFDASICIP--GSITFMPNGCCKTCTPRNE 5070
Query: 2724 ----CNDITARLQYVKVGSCKSEVEVDIHYCQGKCASKAMYSIDINDVQDQCSCCSPTRT 2779
C+ + + G K+ V +++C G C + MYS + CSCC +T
Sbjct: 5071 TRVPCSTVPVTTEVSYAGCTKT---VLMNHCSGSCGTFVMYSAKAQALDHSCSCCKEEKT 5127
Query: 2780 EPMQVALHCTNGSVVYHEVLNAMECKCSPRKC 2811
+V L C NG + H + C+C C
Sbjct: 5128 SQREVVLSCPNGGSLTHTYTHIESCQCQDTVC 5159
Score = 109 bits (273), Expect = 3e-23
Identities = 120/478 (25%), Positives = 181/478 (37%), Gaps = 83/478 (17%)
Query: 827 CPCFHQGKEYAPG-ETVKIGCN-----TCV-------CRDRKWNCTDHVCDATCSTIGMA 873
C CF +Y E VK+ C TC D C CD C+ G
Sbjct: 4428 CDCFMATCKYNNTVEIVKVECEPPPMPTCSNGLQPVRVEDPDGCCWHWECDCYCTGWGDP 4487
Query: 874 HYLTFDGLKYLFPGECQYVLVQDYCGSNPGTFRILVGNKGCS-HPSVKCKKRVTILVEGG 932
HY+TFDGL Y + G C YVLV++ S F + + N C + V C + + + E
Sbjct: 4488 HYVTFDGLYYSYQGNCTYVLVEEISPS-VDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQ 4546
Query: 933 EIEL-------FDGEVNVKR-----PMKDETHFEVVESGRYIILLLGKALSVVWDRHLSI 980
E+ + +V V R P K + EV +SG ++ + + +V LS
Sbjct: 4547 EVLIKTVHMMPMQVQVQVNRQAVALPYK-KYGLEVYQSGINYVVDIPELGVLVSYNGLSF 4605
Query: 981 SVVLK-QTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKVSS-------QCA 1032
SV L + G CG ++D + ++ + + W V+ +
Sbjct: 4606 SVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCPHSS 4665
Query: 1033 DTRKVPLDSSPATCHNNIMKQTMVDSSCRILTSDVFQDCNKLVDPEPYLDVCIYDTCSCE 1092
T K P + P K C+++ +F C+ LV P+ Y D C++D+C
Sbjct: 4666 STTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSC--- 4722
Query: 1093 SIGDCACFCDTIAAYAHVCAQHGKVVTWRTAT--LCPQSCEERNLRENGYECEWRYNSCA 1150
+ + C ++ AYA +CAQ + WR T C C Y +C
Sbjct: 4723 FMPGSSLECASLQAYAALCAQQNICLDWRNHTHGACLVECPSHR----------EYQACG 4772
Query: 1151 PACQVTCQHPEPLACPVQCVEGCHAHCPPGKI-----LDELLQT--CVDPEDCPVCEVAG 1203
PA + TC+ VEGC CP G + D ++T CV P++ P
Sbjct: 4773 PAEEPTCKSSSSQQNNTVLVEGC--FCPEGTMNYAPGFDVCVKTCGCVGPDNVP------ 4824
Query: 1204 RRFASGKKVTLNPSDPEHCQICHCDVVNLTCEACQEPGGLVVPPTDAPVSPTTLYVED 1261
R F EH + D N C + G++ P P T VED
Sbjct: 4825 REFG------------EHFEF---DCKNCVC--LEGGSGIICQPKRCSQKPVTHCVED 4865
Score = 100 bits (249), Expect = 2e-20
Identities = 105/381 (27%), Positives = 156/381 (40%), Gaps = 38/381 (9%)
Query: 35 CSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKR--SFSIIGDFQN---GKRVSLSVYLG 89
C+ +G TFDG YS+ G C+Y+L +F + D + +VS L
Sbjct: 4481 CTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSCPRTLI 4540
Query: 90 EFFD--------IHLF-VNGTVTQGDQRVSMPYASKGLYLETEAGYYKLSGEAYGFVARI 140
+ +H+ + V Q V++PY GL + Y + G +
Sbjct: 4541 VRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELGVLVSY 4600
Query: 141 DGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSS-GEQW 199
+G L R+ N T G CG DD + G + S+ A+ W ++ +
Sbjct: 4601 NGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPH 4660
Query: 200 CERASPPSSSCNISSGEMQKGLWEQ-------CQLLKSTSVFARCHPLVDPEPFVALCEK 252
C +S + ++ K + CQL+K S+FA+CH LV P+ + C
Sbjct: 4661 CPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKD-SLFAQCHALVPPQHYYDACVF 4719
Query: 253 TLCECAG-GLECACPALLEYARTCAQEGMVLYGWTDHS--ACSPVCPAGMEYRQCVSPCA 309
C G LECA +L YA CAQ+ + L W +H+ AC CP+ EY+ C
Sbjct: 4720 DSCFMPGSSLECA--SLQAYAALCAQQNICL-DWRNHTHGACLVECPSHREYQACGPAEE 4776
Query: 310 RTCQSLHINEMCQERCVDGCSCPEGQL-LDEGLCVESTECPCVHSGKRYPP---GTSLSR 365
TC+S ++ V+GC CPEG + G V C CV G P G
Sbjct: 4777 PTCKS-SSSQQNNTVLVEGCFCPEGTMNYAPGFDVCVKTCGCV--GPDNVPREFGEHFEF 4833
Query: 366 DCNTCIC--RNSQWICSNEEC 384
DC C+C S IC + C
Sbjct: 4834 DCKNCVCLEGGSGIICQPKRC 4854
Score = 100 bits (248), Expect = 3e-20
Identities = 108/410 (26%), Positives = 157/410 (38%), Gaps = 64/410 (15%)
Query: 1938 ETCGC---RWTC---PC--VCTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKEQDLEVILH 1989
E C C RW C PC C HI TFDG+ + G C YVL + D +L
Sbjct: 371 EQCVCNAGRWVCKDLPCPGTCALEGGSHITTFDGKTYTFHGDCYYVLAKGDHNDSYALLG 430
Query: 1990 NGA-CSPGARQGCMKSIEVKHSALS--VELHSDMEVTVNGRLVSVPYVGGNMEVNVYGAI 2046
A C +Q C+K++ + V SD V +N V++P+V + V +
Sbjct: 431 ELAPCGSTDKQTCLKTVVLLADKKKNVVVFKSDGSVLLNELQVNLPHVTASFSVFRPSSY 490
Query: 2047 MHEVRFNHLGHIFTFTPQNNEFQLQLSP---------KTFASKTYGLCGICDENGANDFM 2097
HI Q+QL+P + + GLCG + +DF
Sbjct: 491 ----------HIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFK 540
Query: 2098 LRDGTVTTDWKTLVQEWTVQRPGQTCQPILEEQCLVPDSS-----HCQVLLLPL---FAE 2149
G V W Q L++ C + S H LL F
Sbjct: 541 TASGLVEATGAGFANTWKAQSSCHDKLDWLDDPCSLNIESANYAEHWCSLLKKTETPFGR 600
Query: 2150 CHKVLAPATFYAICQQDSC----HQEQVCEVIASYAHLCRTNGVCV-DWRTPDFC---AM 2201
CH + PA +Y C+ D+C +++ +C ++SYA C GV + WR C
Sbjct: 601 CHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACTAKGVMLWGWR-EHVCNKDVG 659
Query: 2202 SCPPSLVYNHCEHGCPRHCDGNVSSCGDH------PSEGCFCPPDKVMLE-GSCVPEEAC 2254
SCP S V+ + C + C ++S H P +GC CP + E G CVP C
Sbjct: 660 SCPNSQVFLYNLTTCQQTC-RSLSEADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAKC 718
Query: 2255 TQCIGEDGVQHQFLEAWVPDHQPCQICTCLSG----RKVNCTTQPCPTAK 2300
+ C + +LEA + + C C G R++ Q C K
Sbjct: 719 S-CYH----RGLYLEAGDVVVRQEERCVCRDGRLHCRQIRLIGQSCTAPK 763
Score = 99.8 bits (247), Expect = 3e-20
Identities = 104/381 (27%), Positives = 154/381 (40%), Gaps = 46/381 (12%)
Query: 1949 VCTGSSTRHIVTFDGQNFKLTGSCSYVLFQN---KEQDLEVILHNGACSPGARQGCMKSI 2005
VC+ H TFDG F+ G C Y + ++ V L G A G +
Sbjct: 36 VCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGPGQAEAPAGVESIL 95
Query: 2006 -EVKHSALSVELHSDMEVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHLGHIFTFTPQ 2064
+K + + H +NG +VS P+ + + A + ++ G + +
Sbjct: 96 LTIKDDTIYLTRHL---AVLNGAVVSTPHYSPGLLIEKSDA--YTKVYSRAGLTLMWN-R 149
Query: 2065 NNEFQLQLSPKTFASKTYGLCGICDENGANDF--MLRDGTVTTDWKTLVQEWTVQRPGQT 2122
+ L+L K F + T GLCG D NG + L DG + + + + + +P
Sbjct: 150 EDALMLELDTK-FRNHTCGLCG--DYNGLQSYSEFLSDGVLFSPLEFGNMQ-KINQPDVV 205
Query: 2123 CQPILEEQCLVPDSSH---CQVLLLP-LFAECHKVLAPATFYAICQQDSCH----QEQVC 2174
C+ EE S H C+ LL FA+C ++ + CQQD C VC
Sbjct: 206 CEDPEEEVAPASCSEHRAECERLLTAEAFADCQDLVPLEPYLRACQQDRCRCPGGDTCVC 265
Query: 2175 EVIASYAHLC-RTNGVCVDWRTPDFCAMSCPPSLVYNHCEHGCPRHCDG-NVSS-CGDHP 2231
+A ++ C G +WRT C +CP +LVY C C VSS C +H
Sbjct: 266 STVAEFSRQCSHAGGRPGNWRTATLCPKTCPGNLVYLESGSPCMDTCSHLEVSSLCEEHR 325
Query: 2232 SEGCFCPPDKV---MLEGSCVPEEACTQCIGEDGVQHQFLEAWVPDHQ---PCQICTCLS 2285
+GCFCP V + + CVP C + H L + P + C+ C C +
Sbjct: 326 MDGCFCPEGTVYDDIGDSGCVPVSQCHCRL------HGHL--YTPGQEITNDCEQCVCNA 377
Query: 2286 GRKVNCTTQPCPTAKAPTCGL 2306
GR V C PCP TC L
Sbjct: 378 GRWV-CKDLPCP----GTCAL 393
>gi|239755545 PREDICTED: otogelin isoform 1 [Homo sapiens]
Length = 2852
Score = 654 bits (1688), Expect = 0.0
Identities = 393/1135 (34%), Positives = 560/1135 (49%), Gaps = 80/1135 (7%)
Query: 35 CSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRSFSIIGDFQNGKRVSLSVY-----LG 89
C +G V TFDG Y +G SY L G + S N + S Y +
Sbjct: 79 CRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVS 138
Query: 90 EFF----DIHLFVNGTVTQGDQRVSMPYASKGLYLETEAGYYKLSGEAYGFVARIDGSGN 145
FF +IHL VT G RV +P+ L+ AGY + ++ F DG+
Sbjct: 139 LFFVGEQEIHLAKE--VTHGGMRVQLPHVMGSARLQQLAGYVIVRHQS-AFTLAWDGASA 195
Query: 146 FQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGEQ--WCERA 203
+ +S T GLCGN N +DD +T G LT D +F +SW + Q +
Sbjct: 196 VYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTS 255
Query: 204 SPPSSSCNISSGEMQKGLWEQCQLLKSTSVFARCHPLVDPEPFVALCEKTLCECAGGLEC 263
S P C + +G++EQC+ L F CH V P PF A C LC+ G +
Sbjct: 256 SLPRPPCLQQNPGTMQGVYEQCEALLRPP-FDACHAYVSPLPFTASCTSDLCQSMGDVAT 314
Query: 264 ACPALLEYARTCAQEGMVLYGW-TDHSACSPVCPA-GMEYRQCVSPCARTCQSLHINEMC 321
C AL EYAR CAQ G L GW T C+ C Y +C++ C +C H C
Sbjct: 315 WCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASC---HPRASC 371
Query: 322 QER---CVDGCSCPEGQLLDEGLCVESTECPCVHSGKRYPPGTSLSRDCNTCICRNSQWI 378
+ CVDGC CP G + ++G CV ECPC G YPPG+ + DCNTC C + +W
Sbjct: 372 VDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWE 431
Query: 379 CSNEECPGECLVTGQSHFKSFDNRYFTFSGICQYLLARDCQDHSFSIVIETVQCADDRDA 438
CS CP EC VTG HF +FD R +TF CQY+LA+ +F++ ++ C ++D
Sbjct: 432 CSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDG 491
Query: 439 VCTRSVTVRLPGLHNSLVKLKHGAGVAMDGQDVQLPLLKGD---LRIQHTVTASVRLSYG 495
C +SV+V L V L V + Q +P D +R +V VR + G
Sbjct: 492 ACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVG 551
Query: 496 EDLQMDWDGRGRLLVKLSPVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWKL 555
+ D +G RL +++ + T GLCG +NGN DDFL+P G+ E + FGN+WK
Sbjct: 552 VRVLYDREGL-RLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKT 610
Query: 556 HGDCQDL-QKQHSDPCALNPRMTRFSEEACAVLTSPTFEACHRAVSPLPYLRNCRYDVCS 614
C L DPC ++ + +S +AC+VLT F C +SP+PY CR D C
Sbjct: 611 LSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACR 670
Query: 615 CSDGRECLCGALASYAAACAGRGVRVAWR-EPGRCELNCPKGQVYLQCGTPCNLTCRSLS 673
C G+ CLC LA YA C G+ V +R C L+C + Y C PC TC+ L+
Sbjct: 671 C--GQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLA 728
Query: 674 YP--------DEECNEACLEGCFCPPGLYMDERGD-CVPKAQCPCYYDGEIFQPEDIFSD 724
P D+ + C+EGC CPP Y+D + D CVP+ QC C++ G + P D
Sbjct: 729 SPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIP 788
Query: 725 HHTMCYCEDGFMHCTMSGVPGSLLPDAVLSSPLSHRSKRSLSCRPPMVKLVCPADNLRAE 784
C+C+DG M C S P + +C V + C + E
Sbjct: 789 SLGHCHCKDGVMSCD-SRAPAA-------------------ACPAGQVFVNCSDLHTDLE 828
Query: 785 GLECTKTC--QNYDLECMSMG-CVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAPGET 841
L +TC Q +L + G C+SGC CP G++RH + C E CPC +GKEY PG+
Sbjct: 829 -LSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQ 887
Query: 842 VKIGCNTCVCRDRKWNCTDHVCDATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSN 901
V C+TCVC+ + CT H C +TC+ G HY TFDGL + F G C+ LV+ ++
Sbjct: 888 VMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVK---STS 944
Query: 902 PGTFRILVGNKGCSHPSVKCKKRVTILVEGGEIELFDGEVNVKRP---MKDETHFEVVES 958
+F ++V N C + C+K ++I V G + +FD + P + D+
Sbjct: 945 DVSFSVIVENVNCYSSGMICRKFISINV-GNSLIVFDDDSGNPSPESFLDDKQEVHTWRV 1003
Query: 959 GRYIILLLGKA-LSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDL-TSSNLQVEE 1016
G + ++ + ++++WD+ ++ V +Q ++ GLCGNFD N++ T NL++
Sbjct: 1004 GFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLEL-T 1062
Query: 1017 DPVDFGNSWKVSSQCADTRKVPLDSSPATCHNNIMKQTMVDSSCRILTSDVFQDCNKLVD 1076
+P +FG+SW + +C DT P D C N +++ C IL S+VF+ C+ +VD
Sbjct: 1063 NPQEFGSSW-AAVECPDTLD-PRD----MCVLNPLREPFAKKECSILLSEVFEICHPVVD 1116
Query: 1077 PEPYLDVCIYDTCSCESIGDCACFCDTIAAYAHVCAQHGKVVTWRTATLCPQSCE 1131
+ C+ DTC C GDC CFC +++AYAH C QHG V WRT LCP C+
Sbjct: 1117 VTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDCD 1171
Score = 240 bits (612), Expect = 2e-62
Identities = 232/952 (24%), Positives = 362/952 (38%), Gaps = 148/952 (15%)
Query: 1907 DGQTLLKSHRVNCDRGLRPS-CPNSQSPVKVE-ETCGCRWTCPCVCTGSSTRHIVTFDGQ 1964
+GQ + + +C +G P C V+V + C W C C C+ VTFDG
Sbjct: 1994 EGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGS 2053
Query: 1965 NFKLTGSCSYVLFQNKEQDLEV-ILHNGACSPGARQG---CMKSIEVKHSALSVELHS-D 2019
+ L Y+L Q+ ++ L V +L + + G C+ + + H A V + +
Sbjct: 2054 HVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFN 2113
Query: 2020 MEVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHLGHIFTF-TPQNNEFQ--------L 2070
+VTV+ + V P V+ YG R GH++ TP + + Q +
Sbjct: 2114 RKVTVDLQPVWPP-------VSRYG-----FRIEDTGHMYMILTPSDIQIQWLHSSGLMI 2161
Query: 2071 QLSPKTFASKTYGLCGICDENGANDFMLRDGTVT---TDWKTLVQEWTVQRP----GQTC 2123
+ KT ++ +GLCGICD + AND L+DG+V D + W V GQT
Sbjct: 2162 VEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQT- 2220
Query: 2124 QPILEEQCLVPDSSHC-QVLLLPLFAECHKVLAPATFYAICQQDSCHQEQVCEVIASYAH 2182
+ C D S C +++ F+ CH+ + P +F + +D+ + +Q C + Y
Sbjct: 2221 -RFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVA 2279
Query: 2183 LCRTNGVCVDWRTPDFCAMSCPPSLVYNHCEHGC--PRHCDGNVSSCGDHP-----SEGC 2235
+C VC++WR D+C C Y C C P+ C + D EGC
Sbjct: 2280 MCHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGC 2339
Query: 2236 FCPPDKVMLE---GSCVPEEACTQCIGEDGVQHQFLEAWVPDHQPCQICTCLSGRKVNCT 2292
C ++ C+PE C C GV E W C C + +
Sbjct: 2340 VCSEGTILHRRHSALCIPEAKCA-CTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPV 2398
Query: 2293 TQPCPTAKAPTC-GLCEVARLRQNADQCCPEYECVCDPVSCDLPPVPHCERGLQP-TLTN 2350
CP+ + +C EVA L D CC CVC+ C+ P C G + T
Sbjct: 2399 DLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCE-GLAPTCRPGHRLLTHFQ 2457
Query: 2351 PGECRPNFTCACRKEECKRVSPPSCPPHRLPTLRKT--QCCDEYECAC-NCVNSTVSCPL 2407
C P+++C C + C+ PSC ++ + CC Y CAC +C +S C
Sbjct: 2458 EDSCCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQE 2517
Query: 2408 GYLASTATNDCGCTTTTCLPDKVCVHRSTIYPVGQFWEEGCDVCTCTDMEDAVMGLRVAQ 2467
G + + VHR+T ++ C C + +
Sbjct: 2518 G-------------------EALTVHRNTTELCCPLYQ-----CVCENF----------R 2543
Query: 2468 CSQKPCEDSCRSGFTYVLHEGECCGRCLP-SACEVVTGSPRGDSQSSWKSVGSQWASPEN 2526
C Q C G L E RC P +CE + P
Sbjct: 2544 CPQVQC------GLGTALVEVWSPDRCCPYKSCECDCDT-----------------IPVP 2580
Query: 2527 PCLINECVRVKEEVFIQQRNVSCPQLEVPVCPSGFQLSCKTSACCPSCRCERMEACMLNG 2586
C + E ++ EE F S + C C + C+
Sbjct: 2581 RCHLWEKSQLDEE---------------------FMHSVENVCGCAKYECVKAPVCLSRE 2619
Query: 2587 T-VIGPGKTVMI----DVCTTCRCMVQVGVISGF-KLECRKTTCN-PCPLG--YKEENNT 2637
V+ PG+TV+ VC T RC + ++ F ++ C+ C Y+ +
Sbjct: 2620 LGVMQPGQTVVELSADGVCHTSRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDL 2679
Query: 2638 GECCGRCLPTACTIQLRGGQIMTLKRDETLQDGCDTHFCKVNERGEYFWEKRVTGCPPFD 2697
CCG C +C G + C H C G ++ CPP +
Sbjct: 2680 AACCGSCRNVSCLFTFPNGTTSLFLPGASWIADCARHHCSSTPLGAVLVRSPIS-CPPLN 2738
Query: 2698 EHKCLAEGGKIMKIPGTCCDTCEEP--ECNDITARLQYVKVGSCKSEVEVDIHYCQGKCA 2755
E +C GG ++ CC TC+E C +T R+ ++ C+S V++ C G+C
Sbjct: 2739 ETECAKVGGSVVPSLEGCCRTCKEDGRSCKKVTIRMT-IRKNECRSSTPVNLVSCDGRCP 2797
Query: 2756 SKAMYSIDINDVQDQCSCCSPTRTEPMQVALHC-TNGSVVYHEVLNAMECKC 2806
S ++Y+ +IN C CC + V L C TN + V + V +C C
Sbjct: 2798 SASIYNYNINTYARFCKCCREVGLQRRSVQLFCATNATWVPYTVQEPTDCAC 2849
Score = 233 bits (594), Expect = 2e-60
Identities = 150/461 (32%), Positives = 207/461 (44%), Gaps = 58/461 (12%)
Query: 802 MGCVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAPGETVKIGCNTCVCRDRKWNCTDH 861
+ CV GC CP G++ + CVA CPC G Y PG VK CNTC C KW C+
Sbjct: 376 IACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWECSTA 435
Query: 862 VCDATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPGTFRILVGNKGCS-HPSVK 920
VC A CS G H+ TFDG +Y FP CQY+L + + GTF + + N C +
Sbjct: 436 VCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKS---RSSGTFTVTLQNAPCGLNQDGA 492
Query: 921 CKKRVTI-----------LVEGGEIELFDGEVNVKRPMKDETHFEVVE-SGRYIILLLGK 968
C + V++ L + G++ LFD + + P D+ FE+ S ++ +
Sbjct: 493 CVQSVSVILHQDPRRQVTLTQAGDVLLFD-QYKIIPPYTDDA-FEIRRLSSVFLRVRTNV 550
Query: 969 ALSVVWDRH-LSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKV 1027
+ V++DR L + + + Q + E GLCG F+G +D S E P FGNSWK
Sbjct: 551 GVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKT 610
Query: 1028 SSQCAD-TRKVPLDSSPATCHNNIMKQTMVDSSCRILTSDVFQDCNKLVDPEPYLDVCIY 1086
S C+ PLD C ++ + +C +LT ++F C+ + P PY + C
Sbjct: 611 LSACSPLVSGSPLDP----CDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRR 666
Query: 1087 DTCSCESIGDCACFCDTIAAYAHVCAQHGKVVTWRTAT-LCPQSCEERNLRENGYECEWR 1145
D C C C C T+A YAH+C +HG V +R C SCE
Sbjct: 667 DACRCGQ----PCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASK----------E 712
Query: 1146 YNSCAPACQVTCQH-PEPLACPV---------QCVEGCHAHCPPGKILDELLQTCVDPED 1195
Y+ C C TCQ P AC V +CVEGC CPP LD CV
Sbjct: 713 YSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCA--CPPDTYLDTQADLCVPRNQ 770
Query: 1196 CPVCEVAGRRFASGKKVTLNPSDPEHCQICHCDVVNLTCEA 1236
C C G + G SD CHC ++C++
Sbjct: 771 CS-CHFQGVDYPPG------DSDIPSLGHCHCKDGVMSCDS 804
Score = 157 bits (396), Expect = 2e-37
Identities = 110/380 (28%), Positives = 157/380 (41%), Gaps = 31/380 (8%)
Query: 33 ARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRSFSI------IGDFQNG---KRVS 83
A CS+ G TFDG Y+F C Y+LA +F++ G Q+G + VS
Sbjct: 439 AECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVS 498
Query: 84 LSVYLGEFFDIHLFVNGTVTQGDQ-RVSMPYASKGLYLETEAGYYKLSGEAYGFVARIDG 142
+ ++ + L G V DQ ++ PY + + + G D
Sbjct: 499 VILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDR 558
Query: 143 SG-NFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGEQWCE 201
G + + R+ T GLCG FN +DDF++ G S P F NSW S C
Sbjct: 559 EGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSA---CS 615
Query: 202 R--ASPPSSSCNISSGEMQKGLWEQCQLLKSTSVFARCHPLVDPEPFVALCEKTLCECAG 259
+ P C++ + + C +L + +FA C + P P+ C + C C
Sbjct: 616 PLVSGSPLDPCDVHLQAASYSV-QACSVL-TGEMFAPCSAFLSPVPYFEQCRRDACRC-- 671
Query: 260 GLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCARTCQSLHINE 319
G C C L YA C + G+ + AC+ C A EY CV+PC RTCQ L E
Sbjct: 672 GQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPE 731
Query: 320 MC---------QERCVDGCSCPEGQLLD--EGLCVESTECPCVHSGKRYPPGTSLSRDCN 368
C ++ CV+GC+CP LD LCV +C C G YPPG S
Sbjct: 732 ACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLG 791
Query: 369 TCICRNSQWICSNEECPGEC 388
C C++ C + C
Sbjct: 792 HCHCKDGVMSCDSRAPAAAC 811
Score = 136 bits (342), Expect = 3e-31
Identities = 124/453 (27%), Positives = 180/453 (39%), Gaps = 72/453 (15%)
Query: 817 HENRCVALERCPCFHQGKEYAPGETVKIGCNTCVCRDRKWNCTDHVC----------DAT 866
H +C CF+ G+ P C R++N T C D+
Sbjct: 29 HRAKCAPSYLFSCFNGGECVHPA----------FCDCRRFNATGPRCQMVYNAGPERDSI 78
Query: 867 CSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPGTFRILVGN-KGCSHPSVKCKKRV 925
C G H TFDGL Y G+ Y LV + +F I V N C C + V
Sbjct: 79 CRAWGQHHVETFDGLYYYLSGKGSYTLVGRH-EPEGQSFSIQVHNDPQCGSSPYTCSRAV 137
Query: 926 TILVEGGE-----IELFDGEVNVKRPMKDETHFEVVESGR------YIILLLGKALSVVW 974
++ G + E+ G + V+ P V+ S R Y+I+ A ++ W
Sbjct: 138 SLFFVGEQEIHLAKEVTHGGMRVQLP-------HVMGSARLQQLAGYVIVRHQSAFTLAW 190
Query: 975 DRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKVSSQCADT 1034
D ++ + + GLCGN + +DL +S+ ++ +D V+F +SW+ Q +
Sbjct: 191 DGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQ--EQAPNQ 248
Query: 1035 RKVPLDSS---PATCHNNIMKQTMVDSSCRILTSDVFQDCNKLVDPEPYLDVCIYDTCSC 1091
P SS P N V C L F C+ V P P+ C D C
Sbjct: 249 PPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDL--C 306
Query: 1092 ESIGDCACFCDTIAAYAHVCAQHGKVVT-WRT-ATLCPQSCEERNLRENGYECEWRYNSC 1149
+S+GD A +C +A YA CAQ G+ + WRT C C+E+ + YN C
Sbjct: 307 QSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEK---------AFTYNEC 357
Query: 1150 APACQVTCQHPEP--LACPVQCVEGCHAHCPPGKILDELLQTCVDPEDCPVCEVAGRRFA 1207
C +C HP + + CV+GC +CP G I ++ CV P +CP CE G +
Sbjct: 358 IACCPASC-HPRASCVDSEIACVDGC--YCPNGLIFED--GGCVAPAECP-CEFHGTLYP 411
Query: 1208 SGKKVTLNPSDPEHCQICHCDVVNLTCEACQEP 1240
G V E C C C C P
Sbjct: 412 PGSVV------KEDCNTCTCTSGKWECSTAVCP 438
Score = 129 bits (323), Expect = 5e-29
Identities = 101/363 (27%), Positives = 151/363 (41%), Gaps = 58/363 (15%)
Query: 1939 TCGC---RW-----TCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKEQD-LEVILH 1989
TC C +W CP C+ + H TFDG+ + +C Y+L +++ V L
Sbjct: 422 TCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQ 481
Query: 1990 NGACSPGARQGCMKSIEVKHSALSVELHSD----MEVTVNGRL-------VSVPYVGGNM 2038
N C C++S+ SV LH D + +T G + + PY
Sbjct: 482 NAPCGLNQDGACVQSV-------SVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAF 534
Query: 2039 EVNVYGAIMHEVRFNHLGHIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFML 2098
E+ ++ VR N +G + + LQ+ + + T GLCG + N +DF+
Sbjct: 535 EIRRLSSVFLRVRTN-VGVRVLYDREGLRLYLQVDQR-WVEDTVGLCGTFNGNTQDDFLS 592
Query: 2099 RDGTVTTDWKTLVQEWTVQRPGQTCQPILEEQCLVPDSSH----------CQVLLLPLFA 2148
G + + W C P++ L P H C VL +FA
Sbjct: 593 PVGVPESTPQLFGNSWKTL---SACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFA 649
Query: 2149 ECHKVLAPATFYAICQQDSCH--QEQVCEVIASYAHLCRTNGVCVDWRTP-DFCAMSCPP 2205
C L+P ++ C++D+C Q +C +A YAHLCR +G+ VD+R CA+SC
Sbjct: 650 PCSAFLSPVPYFEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEA 709
Query: 2206 SLVYNHCEHGCPRHCDGNVS--SCG---------DHPSEGCFCPPDKVM--LEGSCVPEE 2252
S Y+ C C R C S +CG D EGC CPPD + CVP
Sbjct: 710 SKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRN 769
Query: 2253 ACT 2255
C+
Sbjct: 770 QCS 772
Score = 119 bits (298), Expect = 4e-26
Identities = 103/380 (27%), Positives = 149/380 (39%), Gaps = 50/380 (13%)
Query: 1949 VCTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKE---QDLEVILHNGACSPGARQGCMKSI 2005
+C H+ TFDG + L+G SY L E Q + +HN + C +++
Sbjct: 78 ICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAV 137
Query: 2006 EVKHSALSVELHSDMEVTVNGRLVSVPYVGGNMEVNV---YGAIMHEVRFNHLGHIFTFT 2062
+ E+H EVT G V +P+V G+ + Y + H+ F
Sbjct: 138 SLFFVG-EQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFT------LAW 190
Query: 2063 PQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTVQRPGQ- 2121
+ +++SP+ T+GLCG + + +D + G +T D V W Q P Q
Sbjct: 191 DGASAVYIKMSPELLGW-THGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQP 249
Query: 2122 ---TCQPILEEQCLVPDSS-------HCQVLLLPLFAECHKVLAPATFYAICQQDSCHQ- 2170
T + CL + C+ LL P F CH ++P F A C D C
Sbjct: 250 PGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSM 309
Query: 2171 ---EQVCEVIASYAHLCRTNGVCVD-WRTP-DFCAMSC-PPSLVYNHCEHGCPRHCDGNV 2224
C +A YA C G + WRT C + C + YN C CP C
Sbjct: 310 GDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPR- 368
Query: 2225 SSCGDHP---SEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWVPD----HQP 2277
+SC D +GC+CP + +G CV C C +F P +
Sbjct: 369 ASCVDSEIACVDGCYCPNGLIFEDGGCVAPAEC-PC--------EFHGTLYPPGSVVKED 419
Query: 2278 CQICTCLSGRKVNCTTQPCP 2297
C CTC SG K C+T CP
Sbjct: 420 CNTCTCTSG-KWECSTAVCP 438
Score = 91.3 bits (225), Expect = 1e-17
Identities = 82/333 (24%), Positives = 119/333 (35%), Gaps = 41/333 (12%)
Query: 1888 RPGDVWTLPDQCHTV----TCQPDGQTLLKSHRVNCDRGLRPSCPNSQSPVKVEETCGCR 1943
R GD LP++C P Q + H C RG S + P
Sbjct: 862 RHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRG---SFQCTLHP---------- 908
Query: 1944 WTCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQN-KEQDLEVILHNGACSPGARQGCM 2002
C CT RH TFDG F G+C L ++ + VI+ N C C
Sbjct: 909 --CASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSSGMI-CR 965
Query: 2003 KSIEVKHSALSVELHSDMEVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHLGHIFTFT 2062
K I + + D +G ++ EV+ + + HI
Sbjct: 966 KFISINVGNSLIVFDDD-----SGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLW 1020
Query: 2063 PQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTVQRPGQT 2122
Q +Q P+ + + GLCG D N+ + T+ + W T
Sbjct: 1021 DQRTTVHVQAGPQ-WQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDT 1079
Query: 2123 CQPILEEQCLVPD------SSHCQVLLLPLFAECHKVLAPATFYAICQQDSCHQEQ---- 2172
P + C++ C +LL +F CH V+ FY+ C D+C Q
Sbjct: 1080 LDP--RDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDC 1137
Query: 2173 --VCEVIASYAHLCRTNGVCVDWRTPDFCAMSC 2203
C +++YAH C +GV VDWRTP C C
Sbjct: 1138 ECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDC 1170
Score = 82.8 bits (203), Expect = 4e-15
Identities = 85/360 (23%), Positives = 139/360 (38%), Gaps = 55/360 (15%)
Query: 379 CSNEECPGECLVTGQSHFKSFDNRYFTFSGICQYLLARDCQDHSFSIVIETVQCADDR-- 436
C EC C + F +FD + Y+L++ + + + + C
Sbjct: 2030 CPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDE---MLTVHVLDCKSANLG 2086
Query: 437 ----DAVCTRSVTVRLPGLHNSLVKLKHGAGVAMDGQDVQLPLLKGDLRIQHTVTASVRL 492
C V + + L + + + V +D Q V P+ + RI+ T + L
Sbjct: 2087 HLNWPPFCL--VMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMIL 2144
Query: 493 SYGEDLQMDW-DGRGRLLVKLSPVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVED--- 548
+ D+Q+ W G ++V+ S + GLCG +G+ +D G ED
Sbjct: 2145 T-PSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAP 2203
Query: 549 FGNAWKLHGDCQDLQKQHSDPCALNPRMTRFSEEACA---------VLTSPTFEACHRAV 599
F ++W++ + + TRF ++CA ++++ TF ACHR V
Sbjct: 2204 FLDSWQVPSSLTSVGQ------------TRFRPDSCATTDCSPCLRMVSNRTFSACHRFV 2251
Query: 600 SPLPY----LRNCRYDVCSCSDGRECLCGALASYAAACAGRGVRVAWREPGRCELNCPKG 655
P + +R+ +Y + C AL Y A C V + WR C C
Sbjct: 2252 PPESFCELWIRDTKYV--------QQPCVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSD 2303
Query: 656 QVYLQCGTPCN--LTCRS--LSYPDEECNEACLEGCFCPPGLYMDERGD--CVPKAQCPC 709
Y C T C TC+ L D E + EGC C G + R C+P+A+C C
Sbjct: 2304 STYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCAC 2363
Score = 79.7 bits (195), Expect = 4e-14
Identities = 108/447 (24%), Positives = 164/447 (36%), Gaps = 67/447 (14%)
Query: 798 ECMSMGCVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAPGETVKIGCNTCVCRDRKWN 857
+C+ C+ G L +H + A RC G V++G + C
Sbjct: 1986 DCVRHICLEGQLIRVNQSQHCPQGAAPPRCGIL--------GLAVRVGGDRC-------- 2029
Query: 858 CTDHVCDATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPGTFRIL---VGNKGC 914
C C CS ++TFDG E Y+L Q T +L N G
Sbjct: 2030 CPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS--PDEMLTVHVLDCKSANLGH 2087
Query: 915 SH--PSVKCKKRVTILVEGGEIELFDGEVNVKR----PMKDETHFEVVESGRYIILLLGK 968
+ P +T L I+ F+ +V V P F + ++G ++L
Sbjct: 2088 LNWPPFCLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPS 2147
Query: 969 ALSVVWDRHLSISVV-LKQTYQEKVCGLCGNFDGIQNNDLTSSNLQV---EEDPVDFGNS 1024
+ + W + +V +T + + GLCG DG NDLT + V EDP F +S
Sbjct: 2148 DIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDS 2207
Query: 1025 WKVSSQCADTRKVPLDSSPATCHNNIMKQTMVDSSCRILTSDVFQDCNKLVDPEPYLDVC 1084
W+V S + P +C T R++++ F C++ V PE + ++
Sbjct: 2208 WQVPSSLTSVGQTRF--RPDSCAT-----TDCSPCLRMVSNRTFSACHRFVPPESFCELW 2260
Query: 1085 IYDTCSCESIGDCACFCDTIAAYAHVCAQHGKVVTWRTATLCPQSCEERNLRENGYECEW 1144
I DT + C + Y +C + + WR + CP C +
Sbjct: 2261 IRDTKYVQQP------CVALTVYVAMCHKFHVCIEWRRSDYCPFLCSS----------DS 2304
Query: 1145 RYNSCAPACQ--VTCQHP-----EPLACPVQCVEGCHAHCPPGKILDELLQT-CVDPEDC 1196
Y +C AC+ TCQ +P C V EGC C G IL C+ C
Sbjct: 2305 TYQACVTACEPPKTCQDGILGPLDPEHCQV-LGEGC--VCSEGTILHRRHSALCIPEAKC 2361
Query: 1197 PVCEVAGRRFASGKKVTLNPSDPEHCQ 1223
+ G A G+ T N S CQ
Sbjct: 2362 ACTDSMGVPRALGE--TWNSSLSGCCQ 2386
Score = 74.7 bits (182), Expect = 1e-12
Identities = 89/366 (24%), Positives = 137/366 (37%), Gaps = 38/366 (10%)
Query: 10 LLALALILPGTLCAEGTRGRSSTARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRS 69
+L LA+ + G C RCS+F TFDGS + Y+L+ +
Sbjct: 2017 ILGLAVRVGGDRCCPLWE---CACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEML 2073
Query: 70 FSIIGDFQNGKRVSLS-----------VYLGEFFDIHLFVNGTVTQGDQRVSMPYASKGL 118
+ D ++ L+ +L I F N VT Q V P + G
Sbjct: 2074 TVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRF-NRKVTVDLQPVWPPVSRYGF 2132
Query: 119 YLETEAGYYKLSGEAYGFVARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEG 178
+E Y + + + + SG V S + GLCG + A +D ++G
Sbjct: 2133 RIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDG 2192
Query: 179 TLTS---DPYDFANSWALSSGEQWCERASPPSSSCNISSGEMQKGLWEQCQLLKSTSVFA 235
++ DP F +SW + S + SC + C + S F+
Sbjct: 2193 SVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTD-------CSPCLRMVSNRTFS 2245
Query: 236 RCHPLVDPEPFVALCEKTLCECAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVC 295
CH V PE F CE + + ++ C AL Y C + V W C +C
Sbjct: 2246 ACHRFVPPESF---CELWIRD-TKYVQQPCVALTVYVAMC-HKFHVCIEWRRSDYCPFLC 2300
Query: 296 PAGMEYRQCVSPC--ARTCQSLHINEMCQERCV---DGCSCPEGQLL---DEGLCVESTE 347
+ Y+ CV+ C +TCQ + + E C +GC C EG +L LC+ +
Sbjct: 2301 SSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAK 2360
Query: 348 CPCVHS 353
C C S
Sbjct: 2361 CACTDS 2366
Score = 62.4 bits (150), Expect = 6e-09
Identities = 28/56 (50%), Positives = 35/56 (62%), Gaps = 1/56 (1%)
Query: 1142 CEWRYNSCAPACQVTCQHPEPLAC-PVQCVEGCHAHCPPGKILDELLQTCVDPEDC 1196
CEWRY++CA C TC+ P +C V VEGC CP ++LDE+ Q CV EDC
Sbjct: 1336 CEWRYDACASPCFQTCRDPRAASCRDVPRVEGCVPVCPTPQVLDEVTQRCVYLEDC 1391
Score = 45.4 bits (106), Expect = 8e-04
Identities = 53/200 (26%), Positives = 73/200 (36%), Gaps = 50/200 (25%)
Query: 2342 RGLQPTLTNPGECRPNFTCACRKE-----ECKRVSPPSCPPHRLPTLRKTQCCD-EYECA 2395
R LQ T +C T C+++ EC P SC P + C D E C
Sbjct: 331 RPLQGWRTQLRQC----TVHCKEKAFTYNECIACCPASCHP-------RASCVDSEIACV 379
Query: 2396 CNCVNSTVSCPLGYLASTATNDCGCTTTTCLPDKVCVHRSTIYPVGQFWEEGCDVCTCTD 2455
C CP G + D GC P C T+YP G +E C+ CTCT
Sbjct: 380 DGCY-----CPNGLIFE----DGGCVAPAECP---CEFHGTLYPPGSVVKEDCNTCTCTS 427
Query: 2456 MEDAVMGLRVAQCSQKPCEDSCRSGFTYVLHEGECCGR--CLPSACEVVTGSPRGDSQSS 2513
+ +CS C C T +H GR P+ C+ + R
Sbjct: 428 GK--------WECSTAVCPAEC--SVTGDIHFTTFDGRRYTFPATCQYILAKSR------ 471
Query: 2514 WKSVGSQWASPEN-PCLINE 2532
S G+ + +N PC +N+
Sbjct: 472 --SSGTFTVTLQNAPCGLNQ 489
Score = 34.7 bits (78), Expect = 1.4
Identities = 22/63 (34%), Positives = 28/63 (44%), Gaps = 6/63 (9%)
Query: 290 ACSPVCPAGMEYRQCVSPCARTCQSLHINEMCQERCVDGC--SCPEGQLLDE--GLCVES 345
A P+C Y C SPC +TC+ V+GC CP Q+LDE CV
Sbjct: 1331 AAYPICE--WRYDACASPCFQTCRDPRAASCRDVPRVEGCVPVCPTPQVLDEVTQRCVYL 1388
Query: 346 TEC 348
+C
Sbjct: 1389 EDC 1391
>gi|239755543 PREDICTED: otogelin isoform 2 [Homo sapiens]
Length = 2924
Score = 654 bits (1688), Expect = 0.0
Identities = 393/1135 (34%), Positives = 560/1135 (49%), Gaps = 80/1135 (7%)
Query: 35 CSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRSFSIIGDFQNGKRVSLSVY-----LG 89
C +G V TFDG Y +G SY L G + S N + S Y +
Sbjct: 151 CRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVS 210
Query: 90 EFF----DIHLFVNGTVTQGDQRVSMPYASKGLYLETEAGYYKLSGEAYGFVARIDGSGN 145
FF +IHL VT G RV +P+ L+ AGY + ++ F DG+
Sbjct: 211 LFFVGEQEIHLAKE--VTHGGMRVQLPHVMGSARLQQLAGYVIVRHQS-AFTLAWDGASA 267
Query: 146 FQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGEQ--WCERA 203
+ +S T GLCGN N +DD +T G LT D +F +SW + Q +
Sbjct: 268 VYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTS 327
Query: 204 SPPSSSCNISSGEMQKGLWEQCQLLKSTSVFARCHPLVDPEPFVALCEKTLCECAGGLEC 263
S P C + +G++EQC+ L F CH V P PF A C LC+ G +
Sbjct: 328 SLPRPPCLQQNPGTMQGVYEQCEALLRPP-FDACHAYVSPLPFTASCTSDLCQSMGDVAT 386
Query: 264 ACPALLEYARTCAQEGMVLYGW-TDHSACSPVCPA-GMEYRQCVSPCARTCQSLHINEMC 321
C AL EYAR CAQ G L GW T C+ C Y +C++ C +C H C
Sbjct: 387 WCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASC---HPRASC 443
Query: 322 QER---CVDGCSCPEGQLLDEGLCVESTECPCVHSGKRYPPGTSLSRDCNTCICRNSQWI 378
+ CVDGC CP G + ++G CV ECPC G YPPG+ + DCNTC C + +W
Sbjct: 444 VDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWE 503
Query: 379 CSNEECPGECLVTGQSHFKSFDNRYFTFSGICQYLLARDCQDHSFSIVIETVQCADDRDA 438
CS CP EC VTG HF +FD R +TF CQY+LA+ +F++ ++ C ++D
Sbjct: 504 CSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDG 563
Query: 439 VCTRSVTVRLPGLHNSLVKLKHGAGVAMDGQDVQLPLLKGD---LRIQHTVTASVRLSYG 495
C +SV+V L V L V + Q +P D +R +V VR + G
Sbjct: 564 ACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVG 623
Query: 496 EDLQMDWDGRGRLLVKLSPVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWKL 555
+ D +G RL +++ + T GLCG +NGN DDFL+P G+ E + FGN+WK
Sbjct: 624 VRVLYDREGL-RLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKT 682
Query: 556 HGDCQDL-QKQHSDPCALNPRMTRFSEEACAVLTSPTFEACHRAVSPLPYLRNCRYDVCS 614
C L DPC ++ + +S +AC+VLT F C +SP+PY CR D C
Sbjct: 683 LSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACR 742
Query: 615 CSDGRECLCGALASYAAACAGRGVRVAWR-EPGRCELNCPKGQVYLQCGTPCNLTCRSLS 673
C G+ CLC LA YA C G+ V +R C L+C + Y C PC TC+ L+
Sbjct: 743 C--GQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLA 800
Query: 674 YP--------DEECNEACLEGCFCPPGLYMDERGD-CVPKAQCPCYYDGEIFQPEDIFSD 724
P D+ + C+EGC CPP Y+D + D CVP+ QC C++ G + P D
Sbjct: 801 SPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIP 860
Query: 725 HHTMCYCEDGFMHCTMSGVPGSLLPDAVLSSPLSHRSKRSLSCRPPMVKLVCPADNLRAE 784
C+C+DG M C S P + +C V + C + E
Sbjct: 861 SLGHCHCKDGVMSCD-SRAPAA-------------------ACPAGQVFVNCSDLHTDLE 900
Query: 785 GLECTKTC--QNYDLECMSMG-CVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAPGET 841
L +TC Q +L + G C+SGC CP G++RH + C E CPC +GKEY PG+
Sbjct: 901 -LSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQ 959
Query: 842 VKIGCNTCVCRDRKWNCTDHVCDATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSN 901
V C+TCVC+ + CT H C +TC+ G HY TFDGL + F G C+ LV+ ++
Sbjct: 960 VMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVK---STS 1016
Query: 902 PGTFRILVGNKGCSHPSVKCKKRVTILVEGGEIELFDGEVNVKRP---MKDETHFEVVES 958
+F ++V N C + C+K ++I V G + +FD + P + D+
Sbjct: 1017 DVSFSVIVENVNCYSSGMICRKFISINV-GNSLIVFDDDSGNPSPESFLDDKQEVHTWRV 1075
Query: 959 GRYIILLLGKA-LSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDL-TSSNLQVEE 1016
G + ++ + ++++WD+ ++ V +Q ++ GLCGNFD N++ T NL++
Sbjct: 1076 GFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLEL-T 1134
Query: 1017 DPVDFGNSWKVSSQCADTRKVPLDSSPATCHNNIMKQTMVDSSCRILTSDVFQDCNKLVD 1076
+P +FG+SW + +C DT P D C N +++ C IL S+VF+ C+ +VD
Sbjct: 1135 NPQEFGSSW-AAVECPDTLD-PRD----MCVLNPLREPFAKKECSILLSEVFEICHPVVD 1188
Query: 1077 PEPYLDVCIYDTCSCESIGDCACFCDTIAAYAHVCAQHGKVVTWRTATLCPQSCE 1131
+ C+ DTC C GDC CFC +++AYAH C QHG V WRT LCP C+
Sbjct: 1189 VTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDCD 1243
Score = 240 bits (612), Expect = 2e-62
Identities = 232/952 (24%), Positives = 362/952 (38%), Gaps = 148/952 (15%)
Query: 1907 DGQTLLKSHRVNCDRGLRPS-CPNSQSPVKVE-ETCGCRWTCPCVCTGSSTRHIVTFDGQ 1964
+GQ + + +C +G P C V+V + C W C C C+ VTFDG
Sbjct: 2066 EGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGS 2125
Query: 1965 NFKLTGSCSYVLFQNKEQDLEV-ILHNGACSPGARQG---CMKSIEVKHSALSVELHS-D 2019
+ L Y+L Q+ ++ L V +L + + G C+ + + H A V + +
Sbjct: 2126 HVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFN 2185
Query: 2020 MEVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHLGHIFTF-TPQNNEFQ--------L 2070
+VTV+ + V P V+ YG R GH++ TP + + Q +
Sbjct: 2186 RKVTVDLQPVWPP-------VSRYG-----FRIEDTGHMYMILTPSDIQIQWLHSSGLMI 2233
Query: 2071 QLSPKTFASKTYGLCGICDENGANDFMLRDGTVT---TDWKTLVQEWTVQRP----GQTC 2123
+ KT ++ +GLCGICD + AND L+DG+V D + W V GQT
Sbjct: 2234 VEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQT- 2292
Query: 2124 QPILEEQCLVPDSSHC-QVLLLPLFAECHKVLAPATFYAICQQDSCHQEQVCEVIASYAH 2182
+ C D S C +++ F+ CH+ + P +F + +D+ + +Q C + Y
Sbjct: 2293 -RFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVA 2351
Query: 2183 LCRTNGVCVDWRTPDFCAMSCPPSLVYNHCEHGC--PRHCDGNVSSCGDHP-----SEGC 2235
+C VC++WR D+C C Y C C P+ C + D EGC
Sbjct: 2352 MCHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGC 2411
Query: 2236 FCPPDKVMLE---GSCVPEEACTQCIGEDGVQHQFLEAWVPDHQPCQICTCLSGRKVNCT 2292
C ++ C+PE C C GV E W C C + +
Sbjct: 2412 VCSEGTILHRRHSALCIPEAKCA-CTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPV 2470
Query: 2293 TQPCPTAKAPTC-GLCEVARLRQNADQCCPEYECVCDPVSCDLPPVPHCERGLQP-TLTN 2350
CP+ + +C EVA L D CC CVC+ C+ P C G + T
Sbjct: 2471 DLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCE-GLAPTCRPGHRLLTHFQ 2529
Query: 2351 PGECRPNFTCACRKEECKRVSPPSCPPHRLPTLRKT--QCCDEYECAC-NCVNSTVSCPL 2407
C P+++C C + C+ PSC ++ + CC Y CAC +C +S C
Sbjct: 2530 EDSCCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQE 2589
Query: 2408 GYLASTATNDCGCTTTTCLPDKVCVHRSTIYPVGQFWEEGCDVCTCTDMEDAVMGLRVAQ 2467
G + + VHR+T ++ C C + +
Sbjct: 2590 G-------------------EALTVHRNTTELCCPLYQ-----CVCENF----------R 2615
Query: 2468 CSQKPCEDSCRSGFTYVLHEGECCGRCLP-SACEVVTGSPRGDSQSSWKSVGSQWASPEN 2526
C Q C G L E RC P +CE + P
Sbjct: 2616 CPQVQC------GLGTALVEVWSPDRCCPYKSCECDCDT-----------------IPVP 2652
Query: 2527 PCLINECVRVKEEVFIQQRNVSCPQLEVPVCPSGFQLSCKTSACCPSCRCERMEACMLNG 2586
C + E ++ EE F S + C C + C+
Sbjct: 2653 RCHLWEKSQLDEE---------------------FMHSVENVCGCAKYECVKAPVCLSRE 2691
Query: 2587 T-VIGPGKTVMI----DVCTTCRCMVQVGVISGF-KLECRKTTCN-PCPLG--YKEENNT 2637
V+ PG+TV+ VC T RC + ++ F ++ C+ C Y+ +
Sbjct: 2692 LGVMQPGQTVVELSADGVCHTSRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDL 2751
Query: 2638 GECCGRCLPTACTIQLRGGQIMTLKRDETLQDGCDTHFCKVNERGEYFWEKRVTGCPPFD 2697
CCG C +C G + C H C G ++ CPP +
Sbjct: 2752 AACCGSCRNVSCLFTFPNGTTSLFLPGASWIADCARHHCSSTPLGAVLVRSPIS-CPPLN 2810
Query: 2698 EHKCLAEGGKIMKIPGTCCDTCEEP--ECNDITARLQYVKVGSCKSEVEVDIHYCQGKCA 2755
E +C GG ++ CC TC+E C +T R+ ++ C+S V++ C G+C
Sbjct: 2811 ETECAKVGGSVVPSLEGCCRTCKEDGRSCKKVTIRMT-IRKNECRSSTPVNLVSCDGRCP 2869
Query: 2756 SKAMYSIDINDVQDQCSCCSPTRTEPMQVALHC-TNGSVVYHEVLNAMECKC 2806
S ++Y+ +IN C CC + V L C TN + V + V +C C
Sbjct: 2870 SASIYNYNINTYARFCKCCREVGLQRRSVQLFCATNATWVPYTVQEPTDCAC 2921
Score = 233 bits (594), Expect = 2e-60
Identities = 150/461 (32%), Positives = 207/461 (44%), Gaps = 58/461 (12%)
Query: 802 MGCVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAPGETVKIGCNTCVCRDRKWNCTDH 861
+ CV GC CP G++ + CVA CPC G Y PG VK CNTC C KW C+
Sbjct: 448 IACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWECSTA 507
Query: 862 VCDATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPGTFRILVGNKGCS-HPSVK 920
VC A CS G H+ TFDG +Y FP CQY+L + + GTF + + N C +
Sbjct: 508 VCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKS---RSSGTFTVTLQNAPCGLNQDGA 564
Query: 921 CKKRVTI-----------LVEGGEIELFDGEVNVKRPMKDETHFEVVE-SGRYIILLLGK 968
C + V++ L + G++ LFD + + P D+ FE+ S ++ +
Sbjct: 565 CVQSVSVILHQDPRRQVTLTQAGDVLLFD-QYKIIPPYTDDA-FEIRRLSSVFLRVRTNV 622
Query: 969 ALSVVWDRH-LSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKV 1027
+ V++DR L + + + Q + E GLCG F+G +D S E P FGNSWK
Sbjct: 623 GVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKT 682
Query: 1028 SSQCAD-TRKVPLDSSPATCHNNIMKQTMVDSSCRILTSDVFQDCNKLVDPEPYLDVCIY 1086
S C+ PLD C ++ + +C +LT ++F C+ + P PY + C
Sbjct: 683 LSACSPLVSGSPLDP----CDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRR 738
Query: 1087 DTCSCESIGDCACFCDTIAAYAHVCAQHGKVVTWRTAT-LCPQSCEERNLRENGYECEWR 1145
D C C C C T+A YAH+C +HG V +R C SCE
Sbjct: 739 DACRCGQ----PCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASK----------E 784
Query: 1146 YNSCAPACQVTCQH-PEPLACPV---------QCVEGCHAHCPPGKILDELLQTCVDPED 1195
Y+ C C TCQ P AC V +CVEGC CPP LD CV
Sbjct: 785 YSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCA--CPPDTYLDTQADLCVPRNQ 842
Query: 1196 CPVCEVAGRRFASGKKVTLNPSDPEHCQICHCDVVNLTCEA 1236
C C G + G SD CHC ++C++
Sbjct: 843 CS-CHFQGVDYPPG------DSDIPSLGHCHCKDGVMSCDS 876
Score = 157 bits (396), Expect = 2e-37
Identities = 110/380 (28%), Positives = 157/380 (41%), Gaps = 31/380 (8%)
Query: 33 ARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRSFSI------IGDFQNG---KRVS 83
A CS+ G TFDG Y+F C Y+LA +F++ G Q+G + VS
Sbjct: 511 AECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVS 570
Query: 84 LSVYLGEFFDIHLFVNGTVTQGDQ-RVSMPYASKGLYLETEAGYYKLSGEAYGFVARIDG 142
+ ++ + L G V DQ ++ PY + + + G D
Sbjct: 571 VILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDR 630
Query: 143 SG-NFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGEQWCE 201
G + + R+ T GLCG FN +DDF++ G S P F NSW S C
Sbjct: 631 EGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSA---CS 687
Query: 202 R--ASPPSSSCNISSGEMQKGLWEQCQLLKSTSVFARCHPLVDPEPFVALCEKTLCECAG 259
+ P C++ + + C +L + +FA C + P P+ C + C C
Sbjct: 688 PLVSGSPLDPCDVHLQAASYSV-QACSVL-TGEMFAPCSAFLSPVPYFEQCRRDACRC-- 743
Query: 260 GLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCARTCQSLHINE 319
G C C L YA C + G+ + AC+ C A EY CV+PC RTCQ L E
Sbjct: 744 GQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPE 803
Query: 320 MC---------QERCVDGCSCPEGQLLD--EGLCVESTECPCVHSGKRYPPGTSLSRDCN 368
C ++ CV+GC+CP LD LCV +C C G YPPG S
Sbjct: 804 ACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLG 863
Query: 369 TCICRNSQWICSNEECPGEC 388
C C++ C + C
Sbjct: 864 HCHCKDGVMSCDSRAPAAAC 883
Score = 136 bits (342), Expect = 3e-31
Identities = 124/453 (27%), Positives = 180/453 (39%), Gaps = 72/453 (15%)
Query: 817 HENRCVALERCPCFHQGKEYAPGETVKIGCNTCVCRDRKWNCTDHVC----------DAT 866
H +C CF+ G+ P C R++N T C D+
Sbjct: 101 HRAKCAPSYLFSCFNGGECVHPA----------FCDCRRFNATGPRCQMVYNAGPERDSI 150
Query: 867 CSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPGTFRILVGN-KGCSHPSVKCKKRV 925
C G H TFDGL Y G+ Y LV + +F I V N C C + V
Sbjct: 151 CRAWGQHHVETFDGLYYYLSGKGSYTLVGRH-EPEGQSFSIQVHNDPQCGSSPYTCSRAV 209
Query: 926 TILVEGGE-----IELFDGEVNVKRPMKDETHFEVVESGR------YIILLLGKALSVVW 974
++ G + E+ G + V+ P V+ S R Y+I+ A ++ W
Sbjct: 210 SLFFVGEQEIHLAKEVTHGGMRVQLP-------HVMGSARLQQLAGYVIVRHQSAFTLAW 262
Query: 975 DRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKVSSQCADT 1034
D ++ + + GLCGN + +DL +S+ ++ +D V+F +SW+ Q +
Sbjct: 263 DGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQ--EQAPNQ 320
Query: 1035 RKVPLDSS---PATCHNNIMKQTMVDSSCRILTSDVFQDCNKLVDPEPYLDVCIYDTCSC 1091
P SS P N V C L F C+ V P P+ C D C
Sbjct: 321 PPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDL--C 378
Query: 1092 ESIGDCACFCDTIAAYAHVCAQHGKVVT-WRT-ATLCPQSCEERNLRENGYECEWRYNSC 1149
+S+GD A +C +A YA CAQ G+ + WRT C C+E+ + YN C
Sbjct: 379 QSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEK---------AFTYNEC 429
Query: 1150 APACQVTCQHPEP--LACPVQCVEGCHAHCPPGKILDELLQTCVDPEDCPVCEVAGRRFA 1207
C +C HP + + CV+GC +CP G I ++ CV P +CP CE G +
Sbjct: 430 IACCPASC-HPRASCVDSEIACVDGC--YCPNGLIFED--GGCVAPAECP-CEFHGTLYP 483
Query: 1208 SGKKVTLNPSDPEHCQICHCDVVNLTCEACQEP 1240
G V E C C C C P
Sbjct: 484 PGSVV------KEDCNTCTCTSGKWECSTAVCP 510
Score = 129 bits (323), Expect = 5e-29
Identities = 101/363 (27%), Positives = 151/363 (41%), Gaps = 58/363 (15%)
Query: 1939 TCGC---RW-----TCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKEQD-LEVILH 1989
TC C +W CP C+ + H TFDG+ + +C Y+L +++ V L
Sbjct: 494 TCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQ 553
Query: 1990 NGACSPGARQGCMKSIEVKHSALSVELHSD----MEVTVNGRL-------VSVPYVGGNM 2038
N C C++S+ SV LH D + +T G + + PY
Sbjct: 554 NAPCGLNQDGACVQSV-------SVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAF 606
Query: 2039 EVNVYGAIMHEVRFNHLGHIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFML 2098
E+ ++ VR N +G + + LQ+ + + T GLCG + N +DF+
Sbjct: 607 EIRRLSSVFLRVRTN-VGVRVLYDREGLRLYLQVDQR-WVEDTVGLCGTFNGNTQDDFLS 664
Query: 2099 RDGTVTTDWKTLVQEWTVQRPGQTCQPILEEQCLVPDSSH----------CQVLLLPLFA 2148
G + + W C P++ L P H C VL +FA
Sbjct: 665 PVGVPESTPQLFGNSWKTL---SACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFA 721
Query: 2149 ECHKVLAPATFYAICQQDSCH--QEQVCEVIASYAHLCRTNGVCVDWRTP-DFCAMSCPP 2205
C L+P ++ C++D+C Q +C +A YAHLCR +G+ VD+R CA+SC
Sbjct: 722 PCSAFLSPVPYFEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEA 781
Query: 2206 SLVYNHCEHGCPRHCDGNVS--SCG---------DHPSEGCFCPPDKVM--LEGSCVPEE 2252
S Y+ C C R C S +CG D EGC CPPD + CVP
Sbjct: 782 SKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRN 841
Query: 2253 ACT 2255
C+
Sbjct: 842 QCS 844
Score = 119 bits (298), Expect = 4e-26
Identities = 103/380 (27%), Positives = 149/380 (39%), Gaps = 50/380 (13%)
Query: 1949 VCTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKE---QDLEVILHNGACSPGARQGCMKSI 2005
+C H+ TFDG + L+G SY L E Q + +HN + C +++
Sbjct: 150 ICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAV 209
Query: 2006 EVKHSALSVELHSDMEVTVNGRLVSVPYVGGNMEVNV---YGAIMHEVRFNHLGHIFTFT 2062
+ E+H EVT G V +P+V G+ + Y + H+ F
Sbjct: 210 SLFFVG-EQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFT------LAW 262
Query: 2063 PQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTVQRPGQ- 2121
+ +++SP+ T+GLCG + + +D + G +T D V W Q P Q
Sbjct: 263 DGASAVYIKMSPELLGW-THGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQP 321
Query: 2122 ---TCQPILEEQCLVPDSS-------HCQVLLLPLFAECHKVLAPATFYAICQQDSCHQ- 2170
T + CL + C+ LL P F CH ++P F A C D C
Sbjct: 322 PGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSM 381
Query: 2171 ---EQVCEVIASYAHLCRTNGVCVD-WRTP-DFCAMSC-PPSLVYNHCEHGCPRHCDGNV 2224
C +A YA C G + WRT C + C + YN C CP C
Sbjct: 382 GDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPR- 440
Query: 2225 SSCGDHP---SEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWVPD----HQP 2277
+SC D +GC+CP + +G CV C C +F P +
Sbjct: 441 ASCVDSEIACVDGCYCPNGLIFEDGGCVAPAEC-PC--------EFHGTLYPPGSVVKED 491
Query: 2278 CQICTCLSGRKVNCTTQPCP 2297
C CTC SG K C+T CP
Sbjct: 492 CNTCTCTSG-KWECSTAVCP 510
Score = 91.3 bits (225), Expect = 1e-17
Identities = 82/333 (24%), Positives = 119/333 (35%), Gaps = 41/333 (12%)
Query: 1888 RPGDVWTLPDQCHTV----TCQPDGQTLLKSHRVNCDRGLRPSCPNSQSPVKVEETCGCR 1943
R GD LP++C P Q + H C RG S + P
Sbjct: 934 RHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRG---SFQCTLHP---------- 980
Query: 1944 WTCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQN-KEQDLEVILHNGACSPGARQGCM 2002
C CT RH TFDG F G+C L ++ + VI+ N C C
Sbjct: 981 --CASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSSGMI-CR 1037
Query: 2003 KSIEVKHSALSVELHSDMEVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHLGHIFTFT 2062
K I + + D +G ++ EV+ + + HI
Sbjct: 1038 KFISINVGNSLIVFDDD-----SGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLW 1092
Query: 2063 PQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTVQRPGQT 2122
Q +Q P+ + + GLCG D N+ + T+ + W T
Sbjct: 1093 DQRTTVHVQAGPQ-WQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDT 1151
Query: 2123 CQPILEEQCLVPD------SSHCQVLLLPLFAECHKVLAPATFYAICQQDSCHQEQ---- 2172
P + C++ C +LL +F CH V+ FY+ C D+C Q
Sbjct: 1152 LDP--RDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDC 1209
Query: 2173 --VCEVIASYAHLCRTNGVCVDWRTPDFCAMSC 2203
C +++YAH C +GV VDWRTP C C
Sbjct: 1210 ECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDC 1242
Score = 82.8 bits (203), Expect = 4e-15
Identities = 85/360 (23%), Positives = 139/360 (38%), Gaps = 55/360 (15%)
Query: 379 CSNEECPGECLVTGQSHFKSFDNRYFTFSGICQYLLARDCQDHSFSIVIETVQCADDR-- 436
C EC C + F +FD + Y+L++ + + + + C
Sbjct: 2102 CPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDE---MLTVHVLDCKSANLG 2158
Query: 437 ----DAVCTRSVTVRLPGLHNSLVKLKHGAGVAMDGQDVQLPLLKGDLRIQHTVTASVRL 492
C V + + L + + + V +D Q V P+ + RI+ T + L
Sbjct: 2159 HLNWPPFCL--VMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMIL 2216
Query: 493 SYGEDLQMDW-DGRGRLLVKLSPVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVED--- 548
+ D+Q+ W G ++V+ S + GLCG +G+ +D G ED
Sbjct: 2217 T-PSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAP 2275
Query: 549 FGNAWKLHGDCQDLQKQHSDPCALNPRMTRFSEEACA---------VLTSPTFEACHRAV 599
F ++W++ + + TRF ++CA ++++ TF ACHR V
Sbjct: 2276 FLDSWQVPSSLTSVGQ------------TRFRPDSCATTDCSPCLRMVSNRTFSACHRFV 2323
Query: 600 SPLPY----LRNCRYDVCSCSDGRECLCGALASYAAACAGRGVRVAWREPGRCELNCPKG 655
P + +R+ +Y + C AL Y A C V + WR C C
Sbjct: 2324 PPESFCELWIRDTKYV--------QQPCVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSD 2375
Query: 656 QVYLQCGTPCN--LTCRS--LSYPDEECNEACLEGCFCPPGLYMDERGD--CVPKAQCPC 709
Y C T C TC+ L D E + EGC C G + R C+P+A+C C
Sbjct: 2376 STYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCAC 2435
Score = 79.7 bits (195), Expect = 4e-14
Identities = 108/447 (24%), Positives = 164/447 (36%), Gaps = 67/447 (14%)
Query: 798 ECMSMGCVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAPGETVKIGCNTCVCRDRKWN 857
+C+ C+ G L +H + A RC G V++G + C
Sbjct: 2058 DCVRHICLEGQLIRVNQSQHCPQGAAPPRCGIL--------GLAVRVGGDRC-------- 2101
Query: 858 CTDHVCDATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPGTFRIL---VGNKGC 914
C C CS ++TFDG E Y+L Q T +L N G
Sbjct: 2102 CPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS--PDEMLTVHVLDCKSANLGH 2159
Query: 915 SH--PSVKCKKRVTILVEGGEIELFDGEVNVKR----PMKDETHFEVVESGRYIILLLGK 968
+ P +T L I+ F+ +V V P F + ++G ++L
Sbjct: 2160 LNWPPFCLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPS 2219
Query: 969 ALSVVWDRHLSISVV-LKQTYQEKVCGLCGNFDGIQNNDLTSSNLQV---EEDPVDFGNS 1024
+ + W + +V +T + + GLCG DG NDLT + V EDP F +S
Sbjct: 2220 DIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDS 2279
Query: 1025 WKVSSQCADTRKVPLDSSPATCHNNIMKQTMVDSSCRILTSDVFQDCNKLVDPEPYLDVC 1084
W+V S + P +C T R++++ F C++ V PE + ++
Sbjct: 2280 WQVPSSLTSVGQTRF--RPDSCAT-----TDCSPCLRMVSNRTFSACHRFVPPESFCELW 2332
Query: 1085 IYDTCSCESIGDCACFCDTIAAYAHVCAQHGKVVTWRTATLCPQSCEERNLRENGYECEW 1144
I DT + C + Y +C + + WR + CP C +
Sbjct: 2333 IRDTKYVQQP------CVALTVYVAMCHKFHVCIEWRRSDYCPFLCSS----------DS 2376
Query: 1145 RYNSCAPACQ--VTCQHP-----EPLACPVQCVEGCHAHCPPGKILDELLQT-CVDPEDC 1196
Y +C AC+ TCQ +P C V EGC C G IL C+ C
Sbjct: 2377 TYQACVTACEPPKTCQDGILGPLDPEHCQV-LGEGC--VCSEGTILHRRHSALCIPEAKC 2433
Query: 1197 PVCEVAGRRFASGKKVTLNPSDPEHCQ 1223
+ G A G+ T N S CQ
Sbjct: 2434 ACTDSMGVPRALGE--TWNSSLSGCCQ 2458
Score = 74.7 bits (182), Expect = 1e-12
Identities = 89/366 (24%), Positives = 137/366 (37%), Gaps = 38/366 (10%)
Query: 10 LLALALILPGTLCAEGTRGRSSTARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRS 69
+L LA+ + G C RCS+F TFDGS + Y+L+ +
Sbjct: 2089 ILGLAVRVGGDRCCPLWE---CACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEML 2145
Query: 70 FSIIGDFQNGKRVSLS-----------VYLGEFFDIHLFVNGTVTQGDQRVSMPYASKGL 118
+ D ++ L+ +L I F N VT Q V P + G
Sbjct: 2146 TVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRF-NRKVTVDLQPVWPPVSRYGF 2204
Query: 119 YLETEAGYYKLSGEAYGFVARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEG 178
+E Y + + + + SG V S + GLCG + A +D ++G
Sbjct: 2205 RIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDG 2264
Query: 179 TLTS---DPYDFANSWALSSGEQWCERASPPSSSCNISSGEMQKGLWEQCQLLKSTSVFA 235
++ DP F +SW + S + SC + C + S F+
Sbjct: 2265 SVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTD-------CSPCLRMVSNRTFS 2317
Query: 236 RCHPLVDPEPFVALCEKTLCECAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVC 295
CH V PE F CE + + ++ C AL Y C + V W C +C
Sbjct: 2318 ACHRFVPPESF---CELWIRD-TKYVQQPCVALTVYVAMC-HKFHVCIEWRRSDYCPFLC 2372
Query: 296 PAGMEYRQCVSPC--ARTCQSLHINEMCQERCV---DGCSCPEGQLL---DEGLCVESTE 347
+ Y+ CV+ C +TCQ + + E C +GC C EG +L LC+ +
Sbjct: 2373 SSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAK 2432
Query: 348 CPCVHS 353
C C S
Sbjct: 2433 CACTDS 2438
Score = 55.5 bits (132), Expect = 7e-07
Identities = 25/56 (44%), Positives = 32/56 (57%), Gaps = 1/56 (1%)
Query: 1142 CEWRYNSCAPACQVTCQHPEPLAC-PVQCVEGCHAHCPPGKILDELLQTCVDPEDC 1196
CEWRY++CA C TC+ P +C V C CP ++LDE+ Q CV EDC
Sbjct: 1408 CEWRYDACASPCFQTCRDPRAASCRDVPRGRSCVPVCPTPQVLDEVTQRCVYLEDC 1463
Score = 45.4 bits (106), Expect = 8e-04
Identities = 53/200 (26%), Positives = 73/200 (36%), Gaps = 50/200 (25%)
Query: 2342 RGLQPTLTNPGECRPNFTCACRKE-----ECKRVSPPSCPPHRLPTLRKTQCCD-EYECA 2395
R LQ T +C T C+++ EC P SC P + C D E C
Sbjct: 403 RPLQGWRTQLRQC----TVHCKEKAFTYNECIACCPASCHP-------RASCVDSEIACV 451
Query: 2396 CNCVNSTVSCPLGYLASTATNDCGCTTTTCLPDKVCVHRSTIYPVGQFWEEGCDVCTCTD 2455
C CP G + D GC P C T+YP G +E C+ CTCT
Sbjct: 452 DGCY-----CPNGLIFE----DGGCVAPAECP---CEFHGTLYPPGSVVKEDCNTCTCTS 499
Query: 2456 MEDAVMGLRVAQCSQKPCEDSCRSGFTYVLHEGECCGR--CLPSACEVVTGSPRGDSQSS 2513
+ +CS C C T +H GR P+ C+ + R
Sbjct: 500 GK--------WECSTAVCPAEC--SVTGDIHFTTFDGRRYTFPATCQYILAKSR------ 543
Query: 2514 WKSVGSQWASPEN-PCLINE 2532
S G+ + +N PC +N+
Sbjct: 544 --SSGTFTVTLQNAPCGLNQ 561
>gi|239749989 PREDICTED: otogelin isoform 2 [Homo sapiens]
Length = 2852
Score = 654 bits (1688), Expect = 0.0
Identities = 393/1135 (34%), Positives = 560/1135 (49%), Gaps = 80/1135 (7%)
Query: 35 CSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRSFSIIGDFQNGKRVSLSVY-----LG 89
C +G V TFDG Y +G SY L G + S N + S Y +
Sbjct: 79 CRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVS 138
Query: 90 EFF----DIHLFVNGTVTQGDQRVSMPYASKGLYLETEAGYYKLSGEAYGFVARIDGSGN 145
FF +IHL VT G RV +P+ L+ AGY + ++ F DG+
Sbjct: 139 LFFVGEQEIHLAKE--VTHGGMRVQLPHVMGSARLQQLAGYVIVRHQS-AFTLAWDGASA 195
Query: 146 FQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGEQ--WCERA 203
+ +S T GLCGN N +DD +T G LT D +F +SW + Q +
Sbjct: 196 VYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTS 255
Query: 204 SPPSSSCNISSGEMQKGLWEQCQLLKSTSVFARCHPLVDPEPFVALCEKTLCECAGGLEC 263
S P C + +G++EQC+ L F CH V P PF A C LC+ G +
Sbjct: 256 SLPRPPCLQQNPGTMQGVYEQCEALLRPP-FDACHAYVSPLPFTASCTSDLCQSMGDVAT 314
Query: 264 ACPALLEYARTCAQEGMVLYGW-TDHSACSPVCPA-GMEYRQCVSPCARTCQSLHINEMC 321
C AL EYAR CAQ G L GW T C+ C Y +C++ C +C H C
Sbjct: 315 WCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASC---HPRASC 371
Query: 322 QER---CVDGCSCPEGQLLDEGLCVESTECPCVHSGKRYPPGTSLSRDCNTCICRNSQWI 378
+ CVDGC CP G + ++G CV ECPC G YPPG+ + DCNTC C + +W
Sbjct: 372 VDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWE 431
Query: 379 CSNEECPGECLVTGQSHFKSFDNRYFTFSGICQYLLARDCQDHSFSIVIETVQCADDRDA 438
CS CP EC VTG HF +FD R +TF CQY+LA+ +F++ ++ C ++D
Sbjct: 432 CSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDG 491
Query: 439 VCTRSVTVRLPGLHNSLVKLKHGAGVAMDGQDVQLPLLKGD---LRIQHTVTASVRLSYG 495
C +SV+V L V L V + Q +P D +R +V VR + G
Sbjct: 492 ACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVG 551
Query: 496 EDLQMDWDGRGRLLVKLSPVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWKL 555
+ D +G RL +++ + T GLCG +NGN DDFL+P G+ E + FGN+WK
Sbjct: 552 VRVLYDREGL-RLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKT 610
Query: 556 HGDCQDL-QKQHSDPCALNPRMTRFSEEACAVLTSPTFEACHRAVSPLPYLRNCRYDVCS 614
C L DPC ++ + +S +AC+VLT F C +SP+PY CR D C
Sbjct: 611 LSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACR 670
Query: 615 CSDGRECLCGALASYAAACAGRGVRVAWR-EPGRCELNCPKGQVYLQCGTPCNLTCRSLS 673
C G+ CLC LA YA C G+ V +R C L+C + Y C PC TC+ L+
Sbjct: 671 C--GQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLA 728
Query: 674 YP--------DEECNEACLEGCFCPPGLYMDERGD-CVPKAQCPCYYDGEIFQPEDIFSD 724
P D+ + C+EGC CPP Y+D + D CVP+ QC C++ G + P D
Sbjct: 729 SPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIP 788
Query: 725 HHTMCYCEDGFMHCTMSGVPGSLLPDAVLSSPLSHRSKRSLSCRPPMVKLVCPADNLRAE 784
C+C+DG M C S P + +C V + C + E
Sbjct: 789 SLGHCHCKDGVMSCD-SRAPAA-------------------ACPAGQVFVNCSDLHTDLE 828
Query: 785 GLECTKTC--QNYDLECMSMG-CVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAPGET 841
L +TC Q +L + G C+SGC CP G++RH + C E CPC +GKEY PG+
Sbjct: 829 -LSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQ 887
Query: 842 VKIGCNTCVCRDRKWNCTDHVCDATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSN 901
V C+TCVC+ + CT H C +TC+ G HY TFDGL + F G C+ LV+ ++
Sbjct: 888 VMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVK---STS 944
Query: 902 PGTFRILVGNKGCSHPSVKCKKRVTILVEGGEIELFDGEVNVKRP---MKDETHFEVVES 958
+F ++V N C + C+K ++I V G + +FD + P + D+
Sbjct: 945 DVSFSVIVENVNCYSSGMICRKFISINV-GNSLIVFDDDSGNPSPESFLDDKQEVHTWRV 1003
Query: 959 GRYIILLLGKA-LSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDL-TSSNLQVEE 1016
G + ++ + ++++WD+ ++ V +Q ++ GLCGNFD N++ T NL++
Sbjct: 1004 GFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLEL-T 1062
Query: 1017 DPVDFGNSWKVSSQCADTRKVPLDSSPATCHNNIMKQTMVDSSCRILTSDVFQDCNKLVD 1076
+P +FG+SW + +C DT P D C N +++ C IL S+VF+ C+ +VD
Sbjct: 1063 NPQEFGSSW-AAVECPDTLD-PRD----MCVLNPLREPFAKKECSILLSEVFEICHPVVD 1116
Query: 1077 PEPYLDVCIYDTCSCESIGDCACFCDTIAAYAHVCAQHGKVVTWRTATLCPQSCE 1131
+ C+ DTC C GDC CFC +++AYAH C QHG V WRT LCP C+
Sbjct: 1117 VTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDCD 1171
Score = 240 bits (612), Expect = 2e-62
Identities = 232/952 (24%), Positives = 362/952 (38%), Gaps = 148/952 (15%)
Query: 1907 DGQTLLKSHRVNCDRGLRPS-CPNSQSPVKVE-ETCGCRWTCPCVCTGSSTRHIVTFDGQ 1964
+GQ + + +C +G P C V+V + C W C C C+ VTFDG
Sbjct: 1994 EGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGS 2053
Query: 1965 NFKLTGSCSYVLFQNKEQDLEV-ILHNGACSPGARQG---CMKSIEVKHSALSVELHS-D 2019
+ L Y+L Q+ ++ L V +L + + G C+ + + H A V + +
Sbjct: 2054 HVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFN 2113
Query: 2020 MEVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHLGHIFTF-TPQNNEFQ--------L 2070
+VTV+ + V P V+ YG R GH++ TP + + Q +
Sbjct: 2114 RKVTVDLQPVWPP-------VSRYG-----FRIEDTGHMYMILTPSDIQIQWLHSSGLMI 2161
Query: 2071 QLSPKTFASKTYGLCGICDENGANDFMLRDGTVT---TDWKTLVQEWTVQRP----GQTC 2123
+ KT ++ +GLCGICD + AND L+DG+V D + W V GQT
Sbjct: 2162 VEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQT- 2220
Query: 2124 QPILEEQCLVPDSSHC-QVLLLPLFAECHKVLAPATFYAICQQDSCHQEQVCEVIASYAH 2182
+ C D S C +++ F+ CH+ + P +F + +D+ + +Q C + Y
Sbjct: 2221 -RFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVA 2279
Query: 2183 LCRTNGVCVDWRTPDFCAMSCPPSLVYNHCEHGC--PRHCDGNVSSCGDHP-----SEGC 2235
+C VC++WR D+C C Y C C P+ C + D EGC
Sbjct: 2280 MCHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGC 2339
Query: 2236 FCPPDKVMLE---GSCVPEEACTQCIGEDGVQHQFLEAWVPDHQPCQICTCLSGRKVNCT 2292
C ++ C+PE C C GV E W C C + +
Sbjct: 2340 VCSEGTILHRRHSALCIPEAKCA-CTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPV 2398
Query: 2293 TQPCPTAKAPTC-GLCEVARLRQNADQCCPEYECVCDPVSCDLPPVPHCERGLQP-TLTN 2350
CP+ + +C EVA L D CC CVC+ C+ P C G + T
Sbjct: 2399 DLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCE-GLAPTCRPGHRLLTHFQ 2457
Query: 2351 PGECRPNFTCACRKEECKRVSPPSCPPHRLPTLRKT--QCCDEYECAC-NCVNSTVSCPL 2407
C P+++C C + C+ PSC ++ + CC Y CAC +C +S C
Sbjct: 2458 EDSCCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQE 2517
Query: 2408 GYLASTATNDCGCTTTTCLPDKVCVHRSTIYPVGQFWEEGCDVCTCTDMEDAVMGLRVAQ 2467
G + + VHR+T ++ C C + +
Sbjct: 2518 G-------------------EALTVHRNTTELCCPLYQ-----CVCENF----------R 2543
Query: 2468 CSQKPCEDSCRSGFTYVLHEGECCGRCLP-SACEVVTGSPRGDSQSSWKSVGSQWASPEN 2526
C Q C G L E RC P +CE + P
Sbjct: 2544 CPQVQC------GLGTALVEVWSPDRCCPYKSCECDCDT-----------------IPVP 2580
Query: 2527 PCLINECVRVKEEVFIQQRNVSCPQLEVPVCPSGFQLSCKTSACCPSCRCERMEACMLNG 2586
C + E ++ EE F S + C C + C+
Sbjct: 2581 RCHLWEKSQLDEE---------------------FMHSVENVCGCAKYECVKAPVCLSRE 2619
Query: 2587 T-VIGPGKTVMI----DVCTTCRCMVQVGVISGF-KLECRKTTCN-PCPLG--YKEENNT 2637
V+ PG+TV+ VC T RC + ++ F ++ C+ C Y+ +
Sbjct: 2620 LGVMQPGQTVVELSADGVCHTSRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDL 2679
Query: 2638 GECCGRCLPTACTIQLRGGQIMTLKRDETLQDGCDTHFCKVNERGEYFWEKRVTGCPPFD 2697
CCG C +C G + C H C G ++ CPP +
Sbjct: 2680 AACCGSCRNVSCLFTFPNGTTSLFLPGASWIADCARHHCSSTPLGAVLVRSPIS-CPPLN 2738
Query: 2698 EHKCLAEGGKIMKIPGTCCDTCEEP--ECNDITARLQYVKVGSCKSEVEVDIHYCQGKCA 2755
E +C GG ++ CC TC+E C +T R+ ++ C+S V++ C G+C
Sbjct: 2739 ETECAKVGGSVVPSLEGCCRTCKEDGRSCKKVTIRMT-IRKNECRSSTPVNLVSCDGRCP 2797
Query: 2756 SKAMYSIDINDVQDQCSCCSPTRTEPMQVALHC-TNGSVVYHEVLNAMECKC 2806
S ++Y+ +IN C CC + V L C TN + V + V +C C
Sbjct: 2798 SASIYNYNINTYARFCKCCREVGLQRRSVQLFCATNATWVPYTVQEPTDCAC 2849
Score = 233 bits (594), Expect = 2e-60
Identities = 150/461 (32%), Positives = 207/461 (44%), Gaps = 58/461 (12%)
Query: 802 MGCVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAPGETVKIGCNTCVCRDRKWNCTDH 861
+ CV GC CP G++ + CVA CPC G Y PG VK CNTC C KW C+
Sbjct: 376 IACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWECSTA 435
Query: 862 VCDATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPGTFRILVGNKGCS-HPSVK 920
VC A CS G H+ TFDG +Y FP CQY+L + + GTF + + N C +
Sbjct: 436 VCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKS---RSSGTFTVTLQNAPCGLNQDGA 492
Query: 921 CKKRVTI-----------LVEGGEIELFDGEVNVKRPMKDETHFEVVE-SGRYIILLLGK 968
C + V++ L + G++ LFD + + P D+ FE+ S ++ +
Sbjct: 493 CVQSVSVILHQDPRRQVTLTQAGDVLLFD-QYKIIPPYTDDA-FEIRRLSSVFLRVRTNV 550
Query: 969 ALSVVWDRH-LSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKV 1027
+ V++DR L + + + Q + E GLCG F+G +D S E P FGNSWK
Sbjct: 551 GVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKT 610
Query: 1028 SSQCAD-TRKVPLDSSPATCHNNIMKQTMVDSSCRILTSDVFQDCNKLVDPEPYLDVCIY 1086
S C+ PLD C ++ + +C +LT ++F C+ + P PY + C
Sbjct: 611 LSACSPLVSGSPLDP----CDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRR 666
Query: 1087 DTCSCESIGDCACFCDTIAAYAHVCAQHGKVVTWRTAT-LCPQSCEERNLRENGYECEWR 1145
D C C C C T+A YAH+C +HG V +R C SCE
Sbjct: 667 DACRCGQ----PCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASK----------E 712
Query: 1146 YNSCAPACQVTCQH-PEPLACPV---------QCVEGCHAHCPPGKILDELLQTCVDPED 1195
Y+ C C TCQ P AC V +CVEGC CPP LD CV
Sbjct: 713 YSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCA--CPPDTYLDTQADLCVPRNQ 770
Query: 1196 CPVCEVAGRRFASGKKVTLNPSDPEHCQICHCDVVNLTCEA 1236
C C G + G SD CHC ++C++
Sbjct: 771 CS-CHFQGVDYPPG------DSDIPSLGHCHCKDGVMSCDS 804
Score = 157 bits (396), Expect = 2e-37
Identities = 110/380 (28%), Positives = 157/380 (41%), Gaps = 31/380 (8%)
Query: 33 ARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRSFSI------IGDFQNG---KRVS 83
A CS+ G TFDG Y+F C Y+LA +F++ G Q+G + VS
Sbjct: 439 AECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVS 498
Query: 84 LSVYLGEFFDIHLFVNGTVTQGDQ-RVSMPYASKGLYLETEAGYYKLSGEAYGFVARIDG 142
+ ++ + L G V DQ ++ PY + + + G D
Sbjct: 499 VILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDR 558
Query: 143 SG-NFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGEQWCE 201
G + + R+ T GLCG FN +DDF++ G S P F NSW S C
Sbjct: 559 EGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSA---CS 615
Query: 202 R--ASPPSSSCNISSGEMQKGLWEQCQLLKSTSVFARCHPLVDPEPFVALCEKTLCECAG 259
+ P C++ + + C +L + +FA C + P P+ C + C C
Sbjct: 616 PLVSGSPLDPCDVHLQAASYSV-QACSVL-TGEMFAPCSAFLSPVPYFEQCRRDACRC-- 671
Query: 260 GLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCARTCQSLHINE 319
G C C L YA C + G+ + AC+ C A EY CV+PC RTCQ L E
Sbjct: 672 GQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPE 731
Query: 320 MC---------QERCVDGCSCPEGQLLD--EGLCVESTECPCVHSGKRYPPGTSLSRDCN 368
C ++ CV+GC+CP LD LCV +C C G YPPG S
Sbjct: 732 ACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLG 791
Query: 369 TCICRNSQWICSNEECPGEC 388
C C++ C + C
Sbjct: 792 HCHCKDGVMSCDSRAPAAAC 811
Score = 136 bits (342), Expect = 3e-31
Identities = 124/453 (27%), Positives = 180/453 (39%), Gaps = 72/453 (15%)
Query: 817 HENRCVALERCPCFHQGKEYAPGETVKIGCNTCVCRDRKWNCTDHVC----------DAT 866
H +C CF+ G+ P C R++N T C D+
Sbjct: 29 HRAKCAPSYLFSCFNGGECVHPA----------FCDCRRFNATGPRCQMVYNAGPERDSI 78
Query: 867 CSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPGTFRILVGN-KGCSHPSVKCKKRV 925
C G H TFDGL Y G+ Y LV + +F I V N C C + V
Sbjct: 79 CRAWGQHHVETFDGLYYYLSGKGSYTLVGRH-EPEGQSFSIQVHNDPQCGSSPYTCSRAV 137
Query: 926 TILVEGGE-----IELFDGEVNVKRPMKDETHFEVVESGR------YIILLLGKALSVVW 974
++ G + E+ G + V+ P V+ S R Y+I+ A ++ W
Sbjct: 138 SLFFVGEQEIHLAKEVTHGGMRVQLP-------HVMGSARLQQLAGYVIVRHQSAFTLAW 190
Query: 975 DRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKVSSQCADT 1034
D ++ + + GLCGN + +DL +S+ ++ +D V+F +SW+ Q +
Sbjct: 191 DGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQ--EQAPNQ 248
Query: 1035 RKVPLDSS---PATCHNNIMKQTMVDSSCRILTSDVFQDCNKLVDPEPYLDVCIYDTCSC 1091
P SS P N V C L F C+ V P P+ C D C
Sbjct: 249 PPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDL--C 306
Query: 1092 ESIGDCACFCDTIAAYAHVCAQHGKVVT-WRT-ATLCPQSCEERNLRENGYECEWRYNSC 1149
+S+GD A +C +A YA CAQ G+ + WRT C C+E+ + YN C
Sbjct: 307 QSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEK---------AFTYNEC 357
Query: 1150 APACQVTCQHPEP--LACPVQCVEGCHAHCPPGKILDELLQTCVDPEDCPVCEVAGRRFA 1207
C +C HP + + CV+GC +CP G I ++ CV P +CP CE G +
Sbjct: 358 IACCPASC-HPRASCVDSEIACVDGC--YCPNGLIFED--GGCVAPAECP-CEFHGTLYP 411
Query: 1208 SGKKVTLNPSDPEHCQICHCDVVNLTCEACQEP 1240
G V E C C C C P
Sbjct: 412 PGSVV------KEDCNTCTCTSGKWECSTAVCP 438
Score = 129 bits (323), Expect = 5e-29
Identities = 101/363 (27%), Positives = 151/363 (41%), Gaps = 58/363 (15%)
Query: 1939 TCGC---RW-----TCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKEQD-LEVILH 1989
TC C +W CP C+ + H TFDG+ + +C Y+L +++ V L
Sbjct: 422 TCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQ 481
Query: 1990 NGACSPGARQGCMKSIEVKHSALSVELHSD----MEVTVNGRL-------VSVPYVGGNM 2038
N C C++S+ SV LH D + +T G + + PY
Sbjct: 482 NAPCGLNQDGACVQSV-------SVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAF 534
Query: 2039 EVNVYGAIMHEVRFNHLGHIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFML 2098
E+ ++ VR N +G + + LQ+ + + T GLCG + N +DF+
Sbjct: 535 EIRRLSSVFLRVRTN-VGVRVLYDREGLRLYLQVDQR-WVEDTVGLCGTFNGNTQDDFLS 592
Query: 2099 RDGTVTTDWKTLVQEWTVQRPGQTCQPILEEQCLVPDSSH----------CQVLLLPLFA 2148
G + + W C P++ L P H C VL +FA
Sbjct: 593 PVGVPESTPQLFGNSWKTL---SACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFA 649
Query: 2149 ECHKVLAPATFYAICQQDSCH--QEQVCEVIASYAHLCRTNGVCVDWRTP-DFCAMSCPP 2205
C L+P ++ C++D+C Q +C +A YAHLCR +G+ VD+R CA+SC
Sbjct: 650 PCSAFLSPVPYFEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEA 709
Query: 2206 SLVYNHCEHGCPRHCDGNVS--SCG---------DHPSEGCFCPPDKVM--LEGSCVPEE 2252
S Y+ C C R C S +CG D EGC CPPD + CVP
Sbjct: 710 SKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRN 769
Query: 2253 ACT 2255
C+
Sbjct: 770 QCS 772
Score = 119 bits (298), Expect = 4e-26
Identities = 103/380 (27%), Positives = 149/380 (39%), Gaps = 50/380 (13%)
Query: 1949 VCTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKE---QDLEVILHNGACSPGARQGCMKSI 2005
+C H+ TFDG + L+G SY L E Q + +HN + C +++
Sbjct: 78 ICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAV 137
Query: 2006 EVKHSALSVELHSDMEVTVNGRLVSVPYVGGNMEVNV---YGAIMHEVRFNHLGHIFTFT 2062
+ E+H EVT G V +P+V G+ + Y + H+ F
Sbjct: 138 SLFFVG-EQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFT------LAW 190
Query: 2063 PQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTVQRPGQ- 2121
+ +++SP+ T+GLCG + + +D + G +T D V W Q P Q
Sbjct: 191 DGASAVYIKMSPELLGW-THGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQP 249
Query: 2122 ---TCQPILEEQCLVPDSS-------HCQVLLLPLFAECHKVLAPATFYAICQQDSCHQ- 2170
T + CL + C+ LL P F CH ++P F A C D C
Sbjct: 250 PGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSM 309
Query: 2171 ---EQVCEVIASYAHLCRTNGVCVD-WRTP-DFCAMSC-PPSLVYNHCEHGCPRHCDGNV 2224
C +A YA C G + WRT C + C + YN C CP C
Sbjct: 310 GDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPR- 368
Query: 2225 SSCGDHP---SEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWVPD----HQP 2277
+SC D +GC+CP + +G CV C C +F P +
Sbjct: 369 ASCVDSEIACVDGCYCPNGLIFEDGGCVAPAEC-PC--------EFHGTLYPPGSVVKED 419
Query: 2278 CQICTCLSGRKVNCTTQPCP 2297
C CTC SG K C+T CP
Sbjct: 420 CNTCTCTSG-KWECSTAVCP 438
Score = 91.3 bits (225), Expect = 1e-17
Identities = 82/333 (24%), Positives = 119/333 (35%), Gaps = 41/333 (12%)
Query: 1888 RPGDVWTLPDQCHTV----TCQPDGQTLLKSHRVNCDRGLRPSCPNSQSPVKVEETCGCR 1943
R GD LP++C P Q + H C RG S + P
Sbjct: 862 RHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRG---SFQCTLHP---------- 908
Query: 1944 WTCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQN-KEQDLEVILHNGACSPGARQGCM 2002
C CT RH TFDG F G+C L ++ + VI+ N C C
Sbjct: 909 --CASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSSGMI-CR 965
Query: 2003 KSIEVKHSALSVELHSDMEVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHLGHIFTFT 2062
K I + + D +G ++ EV+ + + HI
Sbjct: 966 KFISINVGNSLIVFDDD-----SGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLW 1020
Query: 2063 PQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTVQRPGQT 2122
Q +Q P+ + + GLCG D N+ + T+ + W T
Sbjct: 1021 DQRTTVHVQAGPQ-WQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDT 1079
Query: 2123 CQPILEEQCLVPD------SSHCQVLLLPLFAECHKVLAPATFYAICQQDSCHQEQ---- 2172
P + C++ C +LL +F CH V+ FY+ C D+C Q
Sbjct: 1080 LDP--RDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDC 1137
Query: 2173 --VCEVIASYAHLCRTNGVCVDWRTPDFCAMSC 2203
C +++YAH C +GV VDWRTP C C
Sbjct: 1138 ECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDC 1170
Score = 82.8 bits (203), Expect = 4e-15
Identities = 85/360 (23%), Positives = 139/360 (38%), Gaps = 55/360 (15%)
Query: 379 CSNEECPGECLVTGQSHFKSFDNRYFTFSGICQYLLARDCQDHSFSIVIETVQCADDR-- 436
C EC C + F +FD + Y+L++ + + + + C
Sbjct: 2030 CPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDE---MLTVHVLDCKSANLG 2086
Query: 437 ----DAVCTRSVTVRLPGLHNSLVKLKHGAGVAMDGQDVQLPLLKGDLRIQHTVTASVRL 492
C V + + L + + + V +D Q V P+ + RI+ T + L
Sbjct: 2087 HLNWPPFCL--VMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMIL 2144
Query: 493 SYGEDLQMDW-DGRGRLLVKLSPVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVED--- 548
+ D+Q+ W G ++V+ S + GLCG +G+ +D G ED
Sbjct: 2145 T-PSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAP 2203
Query: 549 FGNAWKLHGDCQDLQKQHSDPCALNPRMTRFSEEACA---------VLTSPTFEACHRAV 599
F ++W++ + + TRF ++CA ++++ TF ACHR V
Sbjct: 2204 FLDSWQVPSSLTSVGQ------------TRFRPDSCATTDCSPCLRMVSNRTFSACHRFV 2251
Query: 600 SPLPY----LRNCRYDVCSCSDGRECLCGALASYAAACAGRGVRVAWREPGRCELNCPKG 655
P + +R+ +Y + C AL Y A C V + WR C C
Sbjct: 2252 PPESFCELWIRDTKYV--------QQPCVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSD 2303
Query: 656 QVYLQCGTPCN--LTCRS--LSYPDEECNEACLEGCFCPPGLYMDERGD--CVPKAQCPC 709
Y C T C TC+ L D E + EGC C G + R C+P+A+C C
Sbjct: 2304 STYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCAC 2363
Score = 79.7 bits (195), Expect = 4e-14
Identities = 108/447 (24%), Positives = 164/447 (36%), Gaps = 67/447 (14%)
Query: 798 ECMSMGCVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAPGETVKIGCNTCVCRDRKWN 857
+C+ C+ G L +H + A RC G V++G + C
Sbjct: 1986 DCVRHICLEGQLIRVNQSQHCPQGAAPPRCGIL--------GLAVRVGGDRC-------- 2029
Query: 858 CTDHVCDATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPGTFRIL---VGNKGC 914
C C CS ++TFDG E Y+L Q T +L N G
Sbjct: 2030 CPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS--PDEMLTVHVLDCKSANLGH 2087
Query: 915 SH--PSVKCKKRVTILVEGGEIELFDGEVNVKR----PMKDETHFEVVESGRYIILLLGK 968
+ P +T L I+ F+ +V V P F + ++G ++L
Sbjct: 2088 LNWPPFCLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPS 2147
Query: 969 ALSVVWDRHLSISVV-LKQTYQEKVCGLCGNFDGIQNNDLTSSNLQV---EEDPVDFGNS 1024
+ + W + +V +T + + GLCG DG NDLT + V EDP F +S
Sbjct: 2148 DIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDS 2207
Query: 1025 WKVSSQCADTRKVPLDSSPATCHNNIMKQTMVDSSCRILTSDVFQDCNKLVDPEPYLDVC 1084
W+V S + P +C T R++++ F C++ V PE + ++
Sbjct: 2208 WQVPSSLTSVGQTRF--RPDSCAT-----TDCSPCLRMVSNRTFSACHRFVPPESFCELW 2260
Query: 1085 IYDTCSCESIGDCACFCDTIAAYAHVCAQHGKVVTWRTATLCPQSCEERNLRENGYECEW 1144
I DT + C + Y +C + + WR + CP C +
Sbjct: 2261 IRDTKYVQQP------CVALTVYVAMCHKFHVCIEWRRSDYCPFLCSS----------DS 2304
Query: 1145 RYNSCAPACQ--VTCQHP-----EPLACPVQCVEGCHAHCPPGKILDELLQT-CVDPEDC 1196
Y +C AC+ TCQ +P C V EGC C G IL C+ C
Sbjct: 2305 TYQACVTACEPPKTCQDGILGPLDPEHCQV-LGEGC--VCSEGTILHRRHSALCIPEAKC 2361
Query: 1197 PVCEVAGRRFASGKKVTLNPSDPEHCQ 1223
+ G A G+ T N S CQ
Sbjct: 2362 ACTDSMGVPRALGE--TWNSSLSGCCQ 2386
Score = 74.7 bits (182), Expect = 1e-12
Identities = 89/366 (24%), Positives = 137/366 (37%), Gaps = 38/366 (10%)
Query: 10 LLALALILPGTLCAEGTRGRSSTARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRS 69
+L LA+ + G C RCS+F TFDGS + Y+L+ +
Sbjct: 2017 ILGLAVRVGGDRCCPLWE---CACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEML 2073
Query: 70 FSIIGDFQNGKRVSLS-----------VYLGEFFDIHLFVNGTVTQGDQRVSMPYASKGL 118
+ D ++ L+ +L I F N VT Q V P + G
Sbjct: 2074 TVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRF-NRKVTVDLQPVWPPVSRYGF 2132
Query: 119 YLETEAGYYKLSGEAYGFVARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEG 178
+E Y + + + + SG V S + GLCG + A +D ++G
Sbjct: 2133 RIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDG 2192
Query: 179 TLTS---DPYDFANSWALSSGEQWCERASPPSSSCNISSGEMQKGLWEQCQLLKSTSVFA 235
++ DP F +SW + S + SC + C + S F+
Sbjct: 2193 SVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTD-------CSPCLRMVSNRTFS 2245
Query: 236 RCHPLVDPEPFVALCEKTLCECAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVC 295
CH V PE F CE + + ++ C AL Y C + V W C +C
Sbjct: 2246 ACHRFVPPESF---CELWIRD-TKYVQQPCVALTVYVAMC-HKFHVCIEWRRSDYCPFLC 2300
Query: 296 PAGMEYRQCVSPC--ARTCQSLHINEMCQERCV---DGCSCPEGQLL---DEGLCVESTE 347
+ Y+ CV+ C +TCQ + + E C +GC C EG +L LC+ +
Sbjct: 2301 SSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAK 2360
Query: 348 CPCVHS 353
C C S
Sbjct: 2361 CACTDS 2366
Score = 62.4 bits (150), Expect = 6e-09
Identities = 28/56 (50%), Positives = 35/56 (62%), Gaps = 1/56 (1%)
Query: 1142 CEWRYNSCAPACQVTCQHPEPLAC-PVQCVEGCHAHCPPGKILDELLQTCVDPEDC 1196
CEWRY++CA C TC+ P +C V VEGC CP ++LDE+ Q CV EDC
Sbjct: 1336 CEWRYDACASPCFQTCRDPRAASCRDVPRVEGCVPVCPTPQVLDEVTQRCVYLEDC 1391
Score = 45.4 bits (106), Expect = 8e-04
Identities = 53/200 (26%), Positives = 73/200 (36%), Gaps = 50/200 (25%)
Query: 2342 RGLQPTLTNPGECRPNFTCACRKE-----ECKRVSPPSCPPHRLPTLRKTQCCD-EYECA 2395
R LQ T +C T C+++ EC P SC P + C D E C
Sbjct: 331 RPLQGWRTQLRQC----TVHCKEKAFTYNECIACCPASCHP-------RASCVDSEIACV 379
Query: 2396 CNCVNSTVSCPLGYLASTATNDCGCTTTTCLPDKVCVHRSTIYPVGQFWEEGCDVCTCTD 2455
C CP G + D GC P C T+YP G +E C+ CTCT
Sbjct: 380 DGCY-----CPNGLIFE----DGGCVAPAECP---CEFHGTLYPPGSVVKEDCNTCTCTS 427
Query: 2456 MEDAVMGLRVAQCSQKPCEDSCRSGFTYVLHEGECCGR--CLPSACEVVTGSPRGDSQSS 2513
+ +CS C C T +H GR P+ C+ + R
Sbjct: 428 GK--------WECSTAVCPAEC--SVTGDIHFTTFDGRRYTFPATCQYILAKSR------ 471
Query: 2514 WKSVGSQWASPEN-PCLINE 2532
S G+ + +N PC +N+
Sbjct: 472 --SSGTFTVTLQNAPCGLNQ 489
Score = 34.7 bits (78), Expect = 1.4
Identities = 22/63 (34%), Positives = 28/63 (44%), Gaps = 6/63 (9%)
Query: 290 ACSPVCPAGMEYRQCVSPCARTCQSLHINEMCQERCVDGC--SCPEGQLLDE--GLCVES 345
A P+C Y C SPC +TC+ V+GC CP Q+LDE CV
Sbjct: 1331 AAYPICE--WRYDACASPCFQTCRDPRAASCRDVPRVEGCVPVCPTPQVLDEVTQRCVYL 1388
Query: 346 TEC 348
+C
Sbjct: 1389 EDC 1391
>gi|239749987 PREDICTED: otogelin isoform 1 [Homo sapiens]
Length = 2924
Score = 654 bits (1688), Expect = 0.0
Identities = 393/1135 (34%), Positives = 560/1135 (49%), Gaps = 80/1135 (7%)
Query: 35 CSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRSFSIIGDFQNGKRVSLSVY-----LG 89
C +G V TFDG Y +G SY L G + S N + S Y +
Sbjct: 151 CRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVS 210
Query: 90 EFF----DIHLFVNGTVTQGDQRVSMPYASKGLYLETEAGYYKLSGEAYGFVARIDGSGN 145
FF +IHL VT G RV +P+ L+ AGY + ++ F DG+
Sbjct: 211 LFFVGEQEIHLAKE--VTHGGMRVQLPHVMGSARLQQLAGYVIVRHQS-AFTLAWDGASA 267
Query: 146 FQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGEQ--WCERA 203
+ +S T GLCGN N +DD +T G LT D +F +SW + Q +
Sbjct: 268 VYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTS 327
Query: 204 SPPSSSCNISSGEMQKGLWEQCQLLKSTSVFARCHPLVDPEPFVALCEKTLCECAGGLEC 263
S P C + +G++EQC+ L F CH V P PF A C LC+ G +
Sbjct: 328 SLPRPPCLQQNPGTMQGVYEQCEALLRPP-FDACHAYVSPLPFTASCTSDLCQSMGDVAT 386
Query: 264 ACPALLEYARTCAQEGMVLYGW-TDHSACSPVCPA-GMEYRQCVSPCARTCQSLHINEMC 321
C AL EYAR CAQ G L GW T C+ C Y +C++ C +C H C
Sbjct: 387 WCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASC---HPRASC 443
Query: 322 QER---CVDGCSCPEGQLLDEGLCVESTECPCVHSGKRYPPGTSLSRDCNTCICRNSQWI 378
+ CVDGC CP G + ++G CV ECPC G YPPG+ + DCNTC C + +W
Sbjct: 444 VDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWE 503
Query: 379 CSNEECPGECLVTGQSHFKSFDNRYFTFSGICQYLLARDCQDHSFSIVIETVQCADDRDA 438
CS CP EC VTG HF +FD R +TF CQY+LA+ +F++ ++ C ++D
Sbjct: 504 CSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDG 563
Query: 439 VCTRSVTVRLPGLHNSLVKLKHGAGVAMDGQDVQLPLLKGD---LRIQHTVTASVRLSYG 495
C +SV+V L V L V + Q +P D +R +V VR + G
Sbjct: 564 ACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVG 623
Query: 496 EDLQMDWDGRGRLLVKLSPVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWKL 555
+ D +G RL +++ + T GLCG +NGN DDFL+P G+ E + FGN+WK
Sbjct: 624 VRVLYDREGL-RLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKT 682
Query: 556 HGDCQDL-QKQHSDPCALNPRMTRFSEEACAVLTSPTFEACHRAVSPLPYLRNCRYDVCS 614
C L DPC ++ + +S +AC+VLT F C +SP+PY CR D C
Sbjct: 683 LSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACR 742
Query: 615 CSDGRECLCGALASYAAACAGRGVRVAWR-EPGRCELNCPKGQVYLQCGTPCNLTCRSLS 673
C G+ CLC LA YA C G+ V +R C L+C + Y C PC TC+ L+
Sbjct: 743 C--GQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLA 800
Query: 674 YP--------DEECNEACLEGCFCPPGLYMDERGD-CVPKAQCPCYYDGEIFQPEDIFSD 724
P D+ + C+EGC CPP Y+D + D CVP+ QC C++ G + P D
Sbjct: 801 SPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIP 860
Query: 725 HHTMCYCEDGFMHCTMSGVPGSLLPDAVLSSPLSHRSKRSLSCRPPMVKLVCPADNLRAE 784
C+C+DG M C S P + +C V + C + E
Sbjct: 861 SLGHCHCKDGVMSCD-SRAPAA-------------------ACPAGQVFVNCSDLHTDLE 900
Query: 785 GLECTKTC--QNYDLECMSMG-CVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAPGET 841
L +TC Q +L + G C+SGC CP G++RH + C E CPC +GKEY PG+
Sbjct: 901 -LSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQ 959
Query: 842 VKIGCNTCVCRDRKWNCTDHVCDATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSN 901
V C+TCVC+ + CT H C +TC+ G HY TFDGL + F G C+ LV+ ++
Sbjct: 960 VMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVK---STS 1016
Query: 902 PGTFRILVGNKGCSHPSVKCKKRVTILVEGGEIELFDGEVNVKRP---MKDETHFEVVES 958
+F ++V N C + C+K ++I V G + +FD + P + D+
Sbjct: 1017 DVSFSVIVENVNCYSSGMICRKFISINV-GNSLIVFDDDSGNPSPESFLDDKQEVHTWRV 1075
Query: 959 GRYIILLLGKA-LSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDL-TSSNLQVEE 1016
G + ++ + ++++WD+ ++ V +Q ++ GLCGNFD N++ T NL++
Sbjct: 1076 GFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLEL-T 1134
Query: 1017 DPVDFGNSWKVSSQCADTRKVPLDSSPATCHNNIMKQTMVDSSCRILTSDVFQDCNKLVD 1076
+P +FG+SW + +C DT P D C N +++ C IL S+VF+ C+ +VD
Sbjct: 1135 NPQEFGSSW-AAVECPDTLD-PRD----MCVLNPLREPFAKKECSILLSEVFEICHPVVD 1188
Query: 1077 PEPYLDVCIYDTCSCESIGDCACFCDTIAAYAHVCAQHGKVVTWRTATLCPQSCE 1131
+ C+ DTC C GDC CFC +++AYAH C QHG V WRT LCP C+
Sbjct: 1189 VTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDCD 1243
Score = 240 bits (612), Expect = 2e-62
Identities = 232/952 (24%), Positives = 362/952 (38%), Gaps = 148/952 (15%)
Query: 1907 DGQTLLKSHRVNCDRGLRPS-CPNSQSPVKVE-ETCGCRWTCPCVCTGSSTRHIVTFDGQ 1964
+GQ + + +C +G P C V+V + C W C C C+ VTFDG
Sbjct: 2066 EGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGS 2125
Query: 1965 NFKLTGSCSYVLFQNKEQDLEV-ILHNGACSPGARQG---CMKSIEVKHSALSVELHS-D 2019
+ L Y+L Q+ ++ L V +L + + G C+ + + H A V + +
Sbjct: 2126 HVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFN 2185
Query: 2020 MEVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHLGHIFTF-TPQNNEFQ--------L 2070
+VTV+ + V P V+ YG R GH++ TP + + Q +
Sbjct: 2186 RKVTVDLQPVWPP-------VSRYG-----FRIEDTGHMYMILTPSDIQIQWLHSSGLMI 2233
Query: 2071 QLSPKTFASKTYGLCGICDENGANDFMLRDGTVT---TDWKTLVQEWTVQRP----GQTC 2123
+ KT ++ +GLCGICD + AND L+DG+V D + W V GQT
Sbjct: 2234 VEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQT- 2292
Query: 2124 QPILEEQCLVPDSSHC-QVLLLPLFAECHKVLAPATFYAICQQDSCHQEQVCEVIASYAH 2182
+ C D S C +++ F+ CH+ + P +F + +D+ + +Q C + Y
Sbjct: 2293 -RFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVA 2351
Query: 2183 LCRTNGVCVDWRTPDFCAMSCPPSLVYNHCEHGC--PRHCDGNVSSCGDHP-----SEGC 2235
+C VC++WR D+C C Y C C P+ C + D EGC
Sbjct: 2352 MCHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGC 2411
Query: 2236 FCPPDKVMLE---GSCVPEEACTQCIGEDGVQHQFLEAWVPDHQPCQICTCLSGRKVNCT 2292
C ++ C+PE C C GV E W C C + +
Sbjct: 2412 VCSEGTILHRRHSALCIPEAKCA-CTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPV 2470
Query: 2293 TQPCPTAKAPTC-GLCEVARLRQNADQCCPEYECVCDPVSCDLPPVPHCERGLQP-TLTN 2350
CP+ + +C EVA L D CC CVC+ C+ P C G + T
Sbjct: 2471 DLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCE-GLAPTCRPGHRLLTHFQ 2529
Query: 2351 PGECRPNFTCACRKEECKRVSPPSCPPHRLPTLRKT--QCCDEYECAC-NCVNSTVSCPL 2407
C P+++C C + C+ PSC ++ + CC Y CAC +C +S C
Sbjct: 2530 EDSCCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQE 2589
Query: 2408 GYLASTATNDCGCTTTTCLPDKVCVHRSTIYPVGQFWEEGCDVCTCTDMEDAVMGLRVAQ 2467
G + + VHR+T ++ C C + +
Sbjct: 2590 G-------------------EALTVHRNTTELCCPLYQ-----CVCENF----------R 2615
Query: 2468 CSQKPCEDSCRSGFTYVLHEGECCGRCLP-SACEVVTGSPRGDSQSSWKSVGSQWASPEN 2526
C Q C G L E RC P +CE + P
Sbjct: 2616 CPQVQC------GLGTALVEVWSPDRCCPYKSCECDCDT-----------------IPVP 2652
Query: 2527 PCLINECVRVKEEVFIQQRNVSCPQLEVPVCPSGFQLSCKTSACCPSCRCERMEACMLNG 2586
C + E ++ EE F S + C C + C+
Sbjct: 2653 RCHLWEKSQLDEE---------------------FMHSVENVCGCAKYECVKAPVCLSRE 2691
Query: 2587 T-VIGPGKTVMI----DVCTTCRCMVQVGVISGF-KLECRKTTCN-PCPLG--YKEENNT 2637
V+ PG+TV+ VC T RC + ++ F ++ C+ C Y+ +
Sbjct: 2692 LGVMQPGQTVVELSADGVCHTSRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDL 2751
Query: 2638 GECCGRCLPTACTIQLRGGQIMTLKRDETLQDGCDTHFCKVNERGEYFWEKRVTGCPPFD 2697
CCG C +C G + C H C G ++ CPP +
Sbjct: 2752 AACCGSCRNVSCLFTFPNGTTSLFLPGASWIADCARHHCSSTPLGAVLVRSPIS-CPPLN 2810
Query: 2698 EHKCLAEGGKIMKIPGTCCDTCEEP--ECNDITARLQYVKVGSCKSEVEVDIHYCQGKCA 2755
E +C GG ++ CC TC+E C +T R+ ++ C+S V++ C G+C
Sbjct: 2811 ETECAKVGGSVVPSLEGCCRTCKEDGRSCKKVTIRMT-IRKNECRSSTPVNLVSCDGRCP 2869
Query: 2756 SKAMYSIDINDVQDQCSCCSPTRTEPMQVALHC-TNGSVVYHEVLNAMECKC 2806
S ++Y+ +IN C CC + V L C TN + V + V +C C
Sbjct: 2870 SASIYNYNINTYARFCKCCREVGLQRRSVQLFCATNATWVPYTVQEPTDCAC 2921
Score = 233 bits (594), Expect = 2e-60
Identities = 150/461 (32%), Positives = 207/461 (44%), Gaps = 58/461 (12%)
Query: 802 MGCVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAPGETVKIGCNTCVCRDRKWNCTDH 861
+ CV GC CP G++ + CVA CPC G Y PG VK CNTC C KW C+
Sbjct: 448 IACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWECSTA 507
Query: 862 VCDATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPGTFRILVGNKGCS-HPSVK 920
VC A CS G H+ TFDG +Y FP CQY+L + + GTF + + N C +
Sbjct: 508 VCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKS---RSSGTFTVTLQNAPCGLNQDGA 564
Query: 921 CKKRVTI-----------LVEGGEIELFDGEVNVKRPMKDETHFEVVE-SGRYIILLLGK 968
C + V++ L + G++ LFD + + P D+ FE+ S ++ +
Sbjct: 565 CVQSVSVILHQDPRRQVTLTQAGDVLLFD-QYKIIPPYTDDA-FEIRRLSSVFLRVRTNV 622
Query: 969 ALSVVWDRH-LSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKV 1027
+ V++DR L + + + Q + E GLCG F+G +D S E P FGNSWK
Sbjct: 623 GVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKT 682
Query: 1028 SSQCAD-TRKVPLDSSPATCHNNIMKQTMVDSSCRILTSDVFQDCNKLVDPEPYLDVCIY 1086
S C+ PLD C ++ + +C +LT ++F C+ + P PY + C
Sbjct: 683 LSACSPLVSGSPLDP----CDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRR 738
Query: 1087 DTCSCESIGDCACFCDTIAAYAHVCAQHGKVVTWRTAT-LCPQSCEERNLRENGYECEWR 1145
D C C C C T+A YAH+C +HG V +R C SCE
Sbjct: 739 DACRCGQ----PCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASK----------E 784
Query: 1146 YNSCAPACQVTCQH-PEPLACPV---------QCVEGCHAHCPPGKILDELLQTCVDPED 1195
Y+ C C TCQ P AC V +CVEGC CPP LD CV
Sbjct: 785 YSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCA--CPPDTYLDTQADLCVPRNQ 842
Query: 1196 CPVCEVAGRRFASGKKVTLNPSDPEHCQICHCDVVNLTCEA 1236
C C G + G SD CHC ++C++
Sbjct: 843 CS-CHFQGVDYPPG------DSDIPSLGHCHCKDGVMSCDS 876
Score = 157 bits (396), Expect = 2e-37
Identities = 110/380 (28%), Positives = 157/380 (41%), Gaps = 31/380 (8%)
Query: 33 ARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRSFSI------IGDFQNG---KRVS 83
A CS+ G TFDG Y+F C Y+LA +F++ G Q+G + VS
Sbjct: 511 AECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVS 570
Query: 84 LSVYLGEFFDIHLFVNGTVTQGDQ-RVSMPYASKGLYLETEAGYYKLSGEAYGFVARIDG 142
+ ++ + L G V DQ ++ PY + + + G D
Sbjct: 571 VILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDR 630
Query: 143 SG-NFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGEQWCE 201
G + + R+ T GLCG FN +DDF++ G S P F NSW S C
Sbjct: 631 EGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSA---CS 687
Query: 202 R--ASPPSSSCNISSGEMQKGLWEQCQLLKSTSVFARCHPLVDPEPFVALCEKTLCECAG 259
+ P C++ + + C +L + +FA C + P P+ C + C C
Sbjct: 688 PLVSGSPLDPCDVHLQAASYSV-QACSVL-TGEMFAPCSAFLSPVPYFEQCRRDACRC-- 743
Query: 260 GLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCARTCQSLHINE 319
G C C L YA C + G+ + AC+ C A EY CV+PC RTCQ L E
Sbjct: 744 GQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPE 803
Query: 320 MC---------QERCVDGCSCPEGQLLD--EGLCVESTECPCVHSGKRYPPGTSLSRDCN 368
C ++ CV+GC+CP LD LCV +C C G YPPG S
Sbjct: 804 ACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLG 863
Query: 369 TCICRNSQWICSNEECPGEC 388
C C++ C + C
Sbjct: 864 HCHCKDGVMSCDSRAPAAAC 883
Score = 136 bits (342), Expect = 3e-31
Identities = 124/453 (27%), Positives = 180/453 (39%), Gaps = 72/453 (15%)
Query: 817 HENRCVALERCPCFHQGKEYAPGETVKIGCNTCVCRDRKWNCTDHVC----------DAT 866
H +C CF+ G+ P C R++N T C D+
Sbjct: 101 HRAKCAPSYLFSCFNGGECVHPA----------FCDCRRFNATGPRCQMVYNAGPERDSI 150
Query: 867 CSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPGTFRILVGN-KGCSHPSVKCKKRV 925
C G H TFDGL Y G+ Y LV + +F I V N C C + V
Sbjct: 151 CRAWGQHHVETFDGLYYYLSGKGSYTLVGRH-EPEGQSFSIQVHNDPQCGSSPYTCSRAV 209
Query: 926 TILVEGGE-----IELFDGEVNVKRPMKDETHFEVVESGR------YIILLLGKALSVVW 974
++ G + E+ G + V+ P V+ S R Y+I+ A ++ W
Sbjct: 210 SLFFVGEQEIHLAKEVTHGGMRVQLP-------HVMGSARLQQLAGYVIVRHQSAFTLAW 262
Query: 975 DRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKVSSQCADT 1034
D ++ + + GLCGN + +DL +S+ ++ +D V+F +SW+ Q +
Sbjct: 263 DGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQ--EQAPNQ 320
Query: 1035 RKVPLDSS---PATCHNNIMKQTMVDSSCRILTSDVFQDCNKLVDPEPYLDVCIYDTCSC 1091
P SS P N V C L F C+ V P P+ C D C
Sbjct: 321 PPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDL--C 378
Query: 1092 ESIGDCACFCDTIAAYAHVCAQHGKVVT-WRT-ATLCPQSCEERNLRENGYECEWRYNSC 1149
+S+GD A +C +A YA CAQ G+ + WRT C C+E+ + YN C
Sbjct: 379 QSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEK---------AFTYNEC 429
Query: 1150 APACQVTCQHPEP--LACPVQCVEGCHAHCPPGKILDELLQTCVDPEDCPVCEVAGRRFA 1207
C +C HP + + CV+GC +CP G I ++ CV P +CP CE G +
Sbjct: 430 IACCPASC-HPRASCVDSEIACVDGC--YCPNGLIFED--GGCVAPAECP-CEFHGTLYP 483
Query: 1208 SGKKVTLNPSDPEHCQICHCDVVNLTCEACQEP 1240
G V E C C C C P
Sbjct: 484 PGSVV------KEDCNTCTCTSGKWECSTAVCP 510
Score = 129 bits (323), Expect = 5e-29
Identities = 101/363 (27%), Positives = 151/363 (41%), Gaps = 58/363 (15%)
Query: 1939 TCGC---RW-----TCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKEQD-LEVILH 1989
TC C +W CP C+ + H TFDG+ + +C Y+L +++ V L
Sbjct: 494 TCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQ 553
Query: 1990 NGACSPGARQGCMKSIEVKHSALSVELHSD----MEVTVNGRL-------VSVPYVGGNM 2038
N C C++S+ SV LH D + +T G + + PY
Sbjct: 554 NAPCGLNQDGACVQSV-------SVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAF 606
Query: 2039 EVNVYGAIMHEVRFNHLGHIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFML 2098
E+ ++ VR N +G + + LQ+ + + T GLCG + N +DF+
Sbjct: 607 EIRRLSSVFLRVRTN-VGVRVLYDREGLRLYLQVDQR-WVEDTVGLCGTFNGNTQDDFLS 664
Query: 2099 RDGTVTTDWKTLVQEWTVQRPGQTCQPILEEQCLVPDSSH----------CQVLLLPLFA 2148
G + + W C P++ L P H C VL +FA
Sbjct: 665 PVGVPESTPQLFGNSWKTL---SACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFA 721
Query: 2149 ECHKVLAPATFYAICQQDSCH--QEQVCEVIASYAHLCRTNGVCVDWRTP-DFCAMSCPP 2205
C L+P ++ C++D+C Q +C +A YAHLCR +G+ VD+R CA+SC
Sbjct: 722 PCSAFLSPVPYFEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEA 781
Query: 2206 SLVYNHCEHGCPRHCDGNVS--SCG---------DHPSEGCFCPPDKVM--LEGSCVPEE 2252
S Y+ C C R C S +CG D EGC CPPD + CVP
Sbjct: 782 SKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRN 841
Query: 2253 ACT 2255
C+
Sbjct: 842 QCS 844
Score = 119 bits (298), Expect = 4e-26
Identities = 103/380 (27%), Positives = 149/380 (39%), Gaps = 50/380 (13%)
Query: 1949 VCTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKE---QDLEVILHNGACSPGARQGCMKSI 2005
+C H+ TFDG + L+G SY L E Q + +HN + C +++
Sbjct: 150 ICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAV 209
Query: 2006 EVKHSALSVELHSDMEVTVNGRLVSVPYVGGNMEVNV---YGAIMHEVRFNHLGHIFTFT 2062
+ E+H EVT G V +P+V G+ + Y + H+ F
Sbjct: 210 SLFFVG-EQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFT------LAW 262
Query: 2063 PQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTVQRPGQ- 2121
+ +++SP+ T+GLCG + + +D + G +T D V W Q P Q
Sbjct: 263 DGASAVYIKMSPELLGW-THGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQP 321
Query: 2122 ---TCQPILEEQCLVPDSS-------HCQVLLLPLFAECHKVLAPATFYAICQQDSCHQ- 2170
T + CL + C+ LL P F CH ++P F A C D C
Sbjct: 322 PGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSM 381
Query: 2171 ---EQVCEVIASYAHLCRTNGVCVD-WRTP-DFCAMSC-PPSLVYNHCEHGCPRHCDGNV 2224
C +A YA C G + WRT C + C + YN C CP C
Sbjct: 382 GDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPR- 440
Query: 2225 SSCGDHP---SEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWVPD----HQP 2277
+SC D +GC+CP + +G CV C C +F P +
Sbjct: 441 ASCVDSEIACVDGCYCPNGLIFEDGGCVAPAEC-PC--------EFHGTLYPPGSVVKED 491
Query: 2278 CQICTCLSGRKVNCTTQPCP 2297
C CTC SG K C+T CP
Sbjct: 492 CNTCTCTSG-KWECSTAVCP 510
Score = 91.3 bits (225), Expect = 1e-17
Identities = 82/333 (24%), Positives = 119/333 (35%), Gaps = 41/333 (12%)
Query: 1888 RPGDVWTLPDQCHTV----TCQPDGQTLLKSHRVNCDRGLRPSCPNSQSPVKVEETCGCR 1943
R GD LP++C P Q + H C RG S + P
Sbjct: 934 RHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRG---SFQCTLHP---------- 980
Query: 1944 WTCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQN-KEQDLEVILHNGACSPGARQGCM 2002
C CT RH TFDG F G+C L ++ + VI+ N C C
Sbjct: 981 --CASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSSGMI-CR 1037
Query: 2003 KSIEVKHSALSVELHSDMEVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHLGHIFTFT 2062
K I + + D +G ++ EV+ + + HI
Sbjct: 1038 KFISINVGNSLIVFDDD-----SGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLW 1092
Query: 2063 PQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTVQRPGQT 2122
Q +Q P+ + + GLCG D N+ + T+ + W T
Sbjct: 1093 DQRTTVHVQAGPQ-WQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDT 1151
Query: 2123 CQPILEEQCLVPD------SSHCQVLLLPLFAECHKVLAPATFYAICQQDSCHQEQ---- 2172
P + C++ C +LL +F CH V+ FY+ C D+C Q
Sbjct: 1152 LDP--RDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDC 1209
Query: 2173 --VCEVIASYAHLCRTNGVCVDWRTPDFCAMSC 2203
C +++YAH C +GV VDWRTP C C
Sbjct: 1210 ECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDC 1242
Score = 82.8 bits (203), Expect = 4e-15
Identities = 85/360 (23%), Positives = 139/360 (38%), Gaps = 55/360 (15%)
Query: 379 CSNEECPGECLVTGQSHFKSFDNRYFTFSGICQYLLARDCQDHSFSIVIETVQCADDR-- 436
C EC C + F +FD + Y+L++ + + + + C
Sbjct: 2102 CPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDE---MLTVHVLDCKSANLG 2158
Query: 437 ----DAVCTRSVTVRLPGLHNSLVKLKHGAGVAMDGQDVQLPLLKGDLRIQHTVTASVRL 492
C V + + L + + + V +D Q V P+ + RI+ T + L
Sbjct: 2159 HLNWPPFCL--VMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMIL 2216
Query: 493 SYGEDLQMDW-DGRGRLLVKLSPVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVED--- 548
+ D+Q+ W G ++V+ S + GLCG +G+ +D G ED
Sbjct: 2217 T-PSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAP 2275
Query: 549 FGNAWKLHGDCQDLQKQHSDPCALNPRMTRFSEEACA---------VLTSPTFEACHRAV 599
F ++W++ + + TRF ++CA ++++ TF ACHR V
Sbjct: 2276 FLDSWQVPSSLTSVGQ------------TRFRPDSCATTDCSPCLRMVSNRTFSACHRFV 2323
Query: 600 SPLPY----LRNCRYDVCSCSDGRECLCGALASYAAACAGRGVRVAWREPGRCELNCPKG 655
P + +R+ +Y + C AL Y A C V + WR C C
Sbjct: 2324 PPESFCELWIRDTKYV--------QQPCVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSD 2375
Query: 656 QVYLQCGTPCN--LTCRS--LSYPDEECNEACLEGCFCPPGLYMDERGD--CVPKAQCPC 709
Y C T C TC+ L D E + EGC C G + R C+P+A+C C
Sbjct: 2376 STYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCAC 2435
Score = 79.7 bits (195), Expect = 4e-14
Identities = 108/447 (24%), Positives = 164/447 (36%), Gaps = 67/447 (14%)
Query: 798 ECMSMGCVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAPGETVKIGCNTCVCRDRKWN 857
+C+ C+ G L +H + A RC G V++G + C
Sbjct: 2058 DCVRHICLEGQLIRVNQSQHCPQGAAPPRCGIL--------GLAVRVGGDRC-------- 2101
Query: 858 CTDHVCDATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPGTFRIL---VGNKGC 914
C C CS ++TFDG E Y+L Q T +L N G
Sbjct: 2102 CPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS--PDEMLTVHVLDCKSANLGH 2159
Query: 915 SH--PSVKCKKRVTILVEGGEIELFDGEVNVKR----PMKDETHFEVVESGRYIILLLGK 968
+ P +T L I+ F+ +V V P F + ++G ++L
Sbjct: 2160 LNWPPFCLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPS 2219
Query: 969 ALSVVWDRHLSISVV-LKQTYQEKVCGLCGNFDGIQNNDLTSSNLQV---EEDPVDFGNS 1024
+ + W + +V +T + + GLCG DG NDLT + V EDP F +S
Sbjct: 2220 DIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDS 2279
Query: 1025 WKVSSQCADTRKVPLDSSPATCHNNIMKQTMVDSSCRILTSDVFQDCNKLVDPEPYLDVC 1084
W+V S + P +C T R++++ F C++ V PE + ++
Sbjct: 2280 WQVPSSLTSVGQTRF--RPDSCAT-----TDCSPCLRMVSNRTFSACHRFVPPESFCELW 2332
Query: 1085 IYDTCSCESIGDCACFCDTIAAYAHVCAQHGKVVTWRTATLCPQSCEERNLRENGYECEW 1144
I DT + C + Y +C + + WR + CP C +
Sbjct: 2333 IRDTKYVQQP------CVALTVYVAMCHKFHVCIEWRRSDYCPFLCSS----------DS 2376
Query: 1145 RYNSCAPACQ--VTCQHP-----EPLACPVQCVEGCHAHCPPGKILDELLQT-CVDPEDC 1196
Y +C AC+ TCQ +P C V EGC C G IL C+ C
Sbjct: 2377 TYQACVTACEPPKTCQDGILGPLDPEHCQV-LGEGC--VCSEGTILHRRHSALCIPEAKC 2433
Query: 1197 PVCEVAGRRFASGKKVTLNPSDPEHCQ 1223
+ G A G+ T N S CQ
Sbjct: 2434 ACTDSMGVPRALGE--TWNSSLSGCCQ 2458
Score = 74.7 bits (182), Expect = 1e-12
Identities = 89/366 (24%), Positives = 137/366 (37%), Gaps = 38/366 (10%)
Query: 10 LLALALILPGTLCAEGTRGRSSTARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRS 69
+L LA+ + G C RCS+F TFDGS + Y+L+ +
Sbjct: 2089 ILGLAVRVGGDRCCPLWE---CACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEML 2145
Query: 70 FSIIGDFQNGKRVSLS-----------VYLGEFFDIHLFVNGTVTQGDQRVSMPYASKGL 118
+ D ++ L+ +L I F N VT Q V P + G
Sbjct: 2146 TVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRF-NRKVTVDLQPVWPPVSRYGF 2204
Query: 119 YLETEAGYYKLSGEAYGFVARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEG 178
+E Y + + + + SG V S + GLCG + A +D ++G
Sbjct: 2205 RIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDG 2264
Query: 179 TLTS---DPYDFANSWALSSGEQWCERASPPSSSCNISSGEMQKGLWEQCQLLKSTSVFA 235
++ DP F +SW + S + SC + C + S F+
Sbjct: 2265 SVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTD-------CSPCLRMVSNRTFS 2317
Query: 236 RCHPLVDPEPFVALCEKTLCECAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVC 295
CH V PE F CE + + ++ C AL Y C + V W C +C
Sbjct: 2318 ACHRFVPPESF---CELWIRD-TKYVQQPCVALTVYVAMC-HKFHVCIEWRRSDYCPFLC 2372
Query: 296 PAGMEYRQCVSPC--ARTCQSLHINEMCQERCV---DGCSCPEGQLL---DEGLCVESTE 347
+ Y+ CV+ C +TCQ + + E C +GC C EG +L LC+ +
Sbjct: 2373 SSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAK 2432
Query: 348 CPCVHS 353
C C S
Sbjct: 2433 CACTDS 2438
Score = 55.5 bits (132), Expect = 7e-07
Identities = 25/56 (44%), Positives = 32/56 (57%), Gaps = 1/56 (1%)
Query: 1142 CEWRYNSCAPACQVTCQHPEPLAC-PVQCVEGCHAHCPPGKILDELLQTCVDPEDC 1196
CEWRY++CA C TC+ P +C V C CP ++LDE+ Q CV EDC
Sbjct: 1408 CEWRYDACASPCFQTCRDPRAASCRDVPRGRSCVPVCPTPQVLDEVTQRCVYLEDC 1463
Score = 45.4 bits (106), Expect = 8e-04
Identities = 53/200 (26%), Positives = 73/200 (36%), Gaps = 50/200 (25%)
Query: 2342 RGLQPTLTNPGECRPNFTCACRKE-----ECKRVSPPSCPPHRLPTLRKTQCCD-EYECA 2395
R LQ T +C T C+++ EC P SC P + C D E C
Sbjct: 403 RPLQGWRTQLRQC----TVHCKEKAFTYNECIACCPASCHP-------RASCVDSEIACV 451
Query: 2396 CNCVNSTVSCPLGYLASTATNDCGCTTTTCLPDKVCVHRSTIYPVGQFWEEGCDVCTCTD 2455
C CP G + D GC P C T+YP G +E C+ CTCT
Sbjct: 452 DGCY-----CPNGLIFE----DGGCVAPAECP---CEFHGTLYPPGSVVKEDCNTCTCTS 499
Query: 2456 MEDAVMGLRVAQCSQKPCEDSCRSGFTYVLHEGECCGR--CLPSACEVVTGSPRGDSQSS 2513
+ +CS C C T +H GR P+ C+ + R
Sbjct: 500 GK--------WECSTAVCPAEC--SVTGDIHFTTFDGRRYTFPATCQYILAKSR------ 543
Query: 2514 WKSVGSQWASPEN-PCLINE 2532
S G+ + +N PC +N+
Sbjct: 544 --SSGTFTVTLQNAPCGLNQ 561
>gi|239744300 PREDICTED: otogelin isoform 2 [Homo sapiens]
Length = 2852
Score = 654 bits (1688), Expect = 0.0
Identities = 393/1135 (34%), Positives = 560/1135 (49%), Gaps = 80/1135 (7%)
Query: 35 CSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRSFSIIGDFQNGKRVSLSVY-----LG 89
C +G V TFDG Y +G SY L G + S N + S Y +
Sbjct: 79 CRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVS 138
Query: 90 EFF----DIHLFVNGTVTQGDQRVSMPYASKGLYLETEAGYYKLSGEAYGFVARIDGSGN 145
FF +IHL VT G RV +P+ L+ AGY + ++ F DG+
Sbjct: 139 LFFVGEQEIHLAKE--VTHGGMRVQLPHVMGSARLQQLAGYVIVRHQS-AFTLAWDGASA 195
Query: 146 FQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGEQ--WCERA 203
+ +S T GLCGN N +DD +T G LT D +F +SW + Q +
Sbjct: 196 VYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTS 255
Query: 204 SPPSSSCNISSGEMQKGLWEQCQLLKSTSVFARCHPLVDPEPFVALCEKTLCECAGGLEC 263
S P C + +G++EQC+ L F CH V P PF A C LC+ G +
Sbjct: 256 SLPRPPCLQQNPGTMQGVYEQCEALLRPP-FDACHAYVSPLPFTASCTSDLCQSMGDVAT 314
Query: 264 ACPALLEYARTCAQEGMVLYGW-TDHSACSPVCPA-GMEYRQCVSPCARTCQSLHINEMC 321
C AL EYAR CAQ G L GW T C+ C Y +C++ C +C H C
Sbjct: 315 WCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASC---HPRASC 371
Query: 322 QER---CVDGCSCPEGQLLDEGLCVESTECPCVHSGKRYPPGTSLSRDCNTCICRNSQWI 378
+ CVDGC CP G + ++G CV ECPC G YPPG+ + DCNTC C + +W
Sbjct: 372 VDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWE 431
Query: 379 CSNEECPGECLVTGQSHFKSFDNRYFTFSGICQYLLARDCQDHSFSIVIETVQCADDRDA 438
CS CP EC VTG HF +FD R +TF CQY+LA+ +F++ ++ C ++D
Sbjct: 432 CSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDG 491
Query: 439 VCTRSVTVRLPGLHNSLVKLKHGAGVAMDGQDVQLPLLKGD---LRIQHTVTASVRLSYG 495
C +SV+V L V L V + Q +P D +R +V VR + G
Sbjct: 492 ACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVG 551
Query: 496 EDLQMDWDGRGRLLVKLSPVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWKL 555
+ D +G RL +++ + T GLCG +NGN DDFL+P G+ E + FGN+WK
Sbjct: 552 VRVLYDREGL-RLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKT 610
Query: 556 HGDCQDL-QKQHSDPCALNPRMTRFSEEACAVLTSPTFEACHRAVSPLPYLRNCRYDVCS 614
C L DPC ++ + +S +AC+VLT F C +SP+PY CR D C
Sbjct: 611 LSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACR 670
Query: 615 CSDGRECLCGALASYAAACAGRGVRVAWR-EPGRCELNCPKGQVYLQCGTPCNLTCRSLS 673
C G+ CLC LA YA C G+ V +R C L+C + Y C PC TC+ L+
Sbjct: 671 C--GQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLA 728
Query: 674 YP--------DEECNEACLEGCFCPPGLYMDERGD-CVPKAQCPCYYDGEIFQPEDIFSD 724
P D+ + C+EGC CPP Y+D + D CVP+ QC C++ G + P D
Sbjct: 729 SPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIP 788
Query: 725 HHTMCYCEDGFMHCTMSGVPGSLLPDAVLSSPLSHRSKRSLSCRPPMVKLVCPADNLRAE 784
C+C+DG M C S P + +C V + C + E
Sbjct: 789 SLGHCHCKDGVMSCD-SRAPAA-------------------ACPAGQVFVNCSDLHTDLE 828
Query: 785 GLECTKTC--QNYDLECMSMG-CVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAPGET 841
L +TC Q +L + G C+SGC CP G++RH + C E CPC +GKEY PG+
Sbjct: 829 -LSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQ 887
Query: 842 VKIGCNTCVCRDRKWNCTDHVCDATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSN 901
V C+TCVC+ + CT H C +TC+ G HY TFDGL + F G C+ LV+ ++
Sbjct: 888 VMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVK---STS 944
Query: 902 PGTFRILVGNKGCSHPSVKCKKRVTILVEGGEIELFDGEVNVKRP---MKDETHFEVVES 958
+F ++V N C + C+K ++I V G + +FD + P + D+
Sbjct: 945 DVSFSVIVENVNCYSSGMICRKFISINV-GNSLIVFDDDSGNPSPESFLDDKQEVHTWRV 1003
Query: 959 GRYIILLLGKA-LSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDL-TSSNLQVEE 1016
G + ++ + ++++WD+ ++ V +Q ++ GLCGNFD N++ T NL++
Sbjct: 1004 GFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLEL-T 1062
Query: 1017 DPVDFGNSWKVSSQCADTRKVPLDSSPATCHNNIMKQTMVDSSCRILTSDVFQDCNKLVD 1076
+P +FG+SW + +C DT P D C N +++ C IL S+VF+ C+ +VD
Sbjct: 1063 NPQEFGSSW-AAVECPDTLD-PRD----MCVLNPLREPFAKKECSILLSEVFEICHPVVD 1116
Query: 1077 PEPYLDVCIYDTCSCESIGDCACFCDTIAAYAHVCAQHGKVVTWRTATLCPQSCE 1131
+ C+ DTC C GDC CFC +++AYAH C QHG V WRT LCP C+
Sbjct: 1117 VTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDCD 1171
Score = 240 bits (612), Expect = 2e-62
Identities = 232/952 (24%), Positives = 362/952 (38%), Gaps = 148/952 (15%)
Query: 1907 DGQTLLKSHRVNCDRGLRPS-CPNSQSPVKVE-ETCGCRWTCPCVCTGSSTRHIVTFDGQ 1964
+GQ + + +C +G P C V+V + C W C C C+ VTFDG
Sbjct: 1994 EGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGS 2053
Query: 1965 NFKLTGSCSYVLFQNKEQDLEV-ILHNGACSPGARQG---CMKSIEVKHSALSVELHS-D 2019
+ L Y+L Q+ ++ L V +L + + G C+ + + H A V + +
Sbjct: 2054 HVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFN 2113
Query: 2020 MEVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHLGHIFTF-TPQNNEFQ--------L 2070
+VTV+ + V P V+ YG R GH++ TP + + Q +
Sbjct: 2114 RKVTVDLQPVWPP-------VSRYG-----FRIEDTGHMYMILTPSDIQIQWLHSSGLMI 2161
Query: 2071 QLSPKTFASKTYGLCGICDENGANDFMLRDGTVT---TDWKTLVQEWTVQRP----GQTC 2123
+ KT ++ +GLCGICD + AND L+DG+V D + W V GQT
Sbjct: 2162 VEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQT- 2220
Query: 2124 QPILEEQCLVPDSSHC-QVLLLPLFAECHKVLAPATFYAICQQDSCHQEQVCEVIASYAH 2182
+ C D S C +++ F+ CH+ + P +F + +D+ + +Q C + Y
Sbjct: 2221 -RFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVA 2279
Query: 2183 LCRTNGVCVDWRTPDFCAMSCPPSLVYNHCEHGC--PRHCDGNVSSCGDHP-----SEGC 2235
+C VC++WR D+C C Y C C P+ C + D EGC
Sbjct: 2280 MCHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGC 2339
Query: 2236 FCPPDKVMLE---GSCVPEEACTQCIGEDGVQHQFLEAWVPDHQPCQICTCLSGRKVNCT 2292
C ++ C+PE C C GV E W C C + +
Sbjct: 2340 VCSEGTILHRRHSALCIPEAKCA-CTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPV 2398
Query: 2293 TQPCPTAKAPTC-GLCEVARLRQNADQCCPEYECVCDPVSCDLPPVPHCERGLQP-TLTN 2350
CP+ + +C EVA L D CC CVC+ C+ P C G + T
Sbjct: 2399 DLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCE-GLAPTCRPGHRLLTHFQ 2457
Query: 2351 PGECRPNFTCACRKEECKRVSPPSCPPHRLPTLRKT--QCCDEYECAC-NCVNSTVSCPL 2407
C P+++C C + C+ PSC ++ + CC Y CAC +C +S C
Sbjct: 2458 EDSCCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQE 2517
Query: 2408 GYLASTATNDCGCTTTTCLPDKVCVHRSTIYPVGQFWEEGCDVCTCTDMEDAVMGLRVAQ 2467
G + + VHR+T ++ C C + +
Sbjct: 2518 G-------------------EALTVHRNTTELCCPLYQ-----CVCENF----------R 2543
Query: 2468 CSQKPCEDSCRSGFTYVLHEGECCGRCLP-SACEVVTGSPRGDSQSSWKSVGSQWASPEN 2526
C Q C G L E RC P +CE + P
Sbjct: 2544 CPQVQC------GLGTALVEVWSPDRCCPYKSCECDCDT-----------------IPVP 2580
Query: 2527 PCLINECVRVKEEVFIQQRNVSCPQLEVPVCPSGFQLSCKTSACCPSCRCERMEACMLNG 2586
C + E ++ EE F S + C C + C+
Sbjct: 2581 RCHLWEKSQLDEE---------------------FMHSVENVCGCAKYECVKAPVCLSRE 2619
Query: 2587 T-VIGPGKTVMI----DVCTTCRCMVQVGVISGF-KLECRKTTCN-PCPLG--YKEENNT 2637
V+ PG+TV+ VC T RC + ++ F ++ C+ C Y+ +
Sbjct: 2620 LGVMQPGQTVVELSADGVCHTSRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDL 2679
Query: 2638 GECCGRCLPTACTIQLRGGQIMTLKRDETLQDGCDTHFCKVNERGEYFWEKRVTGCPPFD 2697
CCG C +C G + C H C G ++ CPP +
Sbjct: 2680 AACCGSCRNVSCLFTFPNGTTSLFLPGASWIADCARHHCSSTPLGAVLVRSPIS-CPPLN 2738
Query: 2698 EHKCLAEGGKIMKIPGTCCDTCEEP--ECNDITARLQYVKVGSCKSEVEVDIHYCQGKCA 2755
E +C GG ++ CC TC+E C +T R+ ++ C+S V++ C G+C
Sbjct: 2739 ETECAKVGGSVVPSLEGCCRTCKEDGRSCKKVTIRMT-IRKNECRSSTPVNLVSCDGRCP 2797
Query: 2756 SKAMYSIDINDVQDQCSCCSPTRTEPMQVALHC-TNGSVVYHEVLNAMECKC 2806
S ++Y+ +IN C CC + V L C TN + V + V +C C
Sbjct: 2798 SASIYNYNINTYARFCKCCREVGLQRRSVQLFCATNATWVPYTVQEPTDCAC 2849
Score = 233 bits (594), Expect = 2e-60
Identities = 150/461 (32%), Positives = 207/461 (44%), Gaps = 58/461 (12%)
Query: 802 MGCVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAPGETVKIGCNTCVCRDRKWNCTDH 861
+ CV GC CP G++ + CVA CPC G Y PG VK CNTC C KW C+
Sbjct: 376 IACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWECSTA 435
Query: 862 VCDATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPGTFRILVGNKGCS-HPSVK 920
VC A CS G H+ TFDG +Y FP CQY+L + + GTF + + N C +
Sbjct: 436 VCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKS---RSSGTFTVTLQNAPCGLNQDGA 492
Query: 921 CKKRVTI-----------LVEGGEIELFDGEVNVKRPMKDETHFEVVE-SGRYIILLLGK 968
C + V++ L + G++ LFD + + P D+ FE+ S ++ +
Sbjct: 493 CVQSVSVILHQDPRRQVTLTQAGDVLLFD-QYKIIPPYTDDA-FEIRRLSSVFLRVRTNV 550
Query: 969 ALSVVWDRH-LSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKV 1027
+ V++DR L + + + Q + E GLCG F+G +D S E P FGNSWK
Sbjct: 551 GVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKT 610
Query: 1028 SSQCAD-TRKVPLDSSPATCHNNIMKQTMVDSSCRILTSDVFQDCNKLVDPEPYLDVCIY 1086
S C+ PLD C ++ + +C +LT ++F C+ + P PY + C
Sbjct: 611 LSACSPLVSGSPLDP----CDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRR 666
Query: 1087 DTCSCESIGDCACFCDTIAAYAHVCAQHGKVVTWRTAT-LCPQSCEERNLRENGYECEWR 1145
D C C C C T+A YAH+C +HG V +R C SCE
Sbjct: 667 DACRCGQ----PCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASK----------E 712
Query: 1146 YNSCAPACQVTCQH-PEPLACPV---------QCVEGCHAHCPPGKILDELLQTCVDPED 1195
Y+ C C TCQ P AC V +CVEGC CPP LD CV
Sbjct: 713 YSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCA--CPPDTYLDTQADLCVPRNQ 770
Query: 1196 CPVCEVAGRRFASGKKVTLNPSDPEHCQICHCDVVNLTCEA 1236
C C G + G SD CHC ++C++
Sbjct: 771 CS-CHFQGVDYPPG------DSDIPSLGHCHCKDGVMSCDS 804
Score = 157 bits (396), Expect = 2e-37
Identities = 110/380 (28%), Positives = 157/380 (41%), Gaps = 31/380 (8%)
Query: 33 ARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRSFSI------IGDFQNG---KRVS 83
A CS+ G TFDG Y+F C Y+LA +F++ G Q+G + VS
Sbjct: 439 AECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVS 498
Query: 84 LSVYLGEFFDIHLFVNGTVTQGDQ-RVSMPYASKGLYLETEAGYYKLSGEAYGFVARIDG 142
+ ++ + L G V DQ ++ PY + + + G D
Sbjct: 499 VILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDR 558
Query: 143 SG-NFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGEQWCE 201
G + + R+ T GLCG FN +DDF++ G S P F NSW S C
Sbjct: 559 EGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSA---CS 615
Query: 202 R--ASPPSSSCNISSGEMQKGLWEQCQLLKSTSVFARCHPLVDPEPFVALCEKTLCECAG 259
+ P C++ + + C +L + +FA C + P P+ C + C C
Sbjct: 616 PLVSGSPLDPCDVHLQAASYSV-QACSVL-TGEMFAPCSAFLSPVPYFEQCRRDACRC-- 671
Query: 260 GLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCARTCQSLHINE 319
G C C L YA C + G+ + AC+ C A EY CV+PC RTCQ L E
Sbjct: 672 GQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPE 731
Query: 320 MC---------QERCVDGCSCPEGQLLD--EGLCVESTECPCVHSGKRYPPGTSLSRDCN 368
C ++ CV+GC+CP LD LCV +C C G YPPG S
Sbjct: 732 ACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLG 791
Query: 369 TCICRNSQWICSNEECPGEC 388
C C++ C + C
Sbjct: 792 HCHCKDGVMSCDSRAPAAAC 811
Score = 136 bits (342), Expect = 3e-31
Identities = 124/453 (27%), Positives = 180/453 (39%), Gaps = 72/453 (15%)
Query: 817 HENRCVALERCPCFHQGKEYAPGETVKIGCNTCVCRDRKWNCTDHVC----------DAT 866
H +C CF+ G+ P C R++N T C D+
Sbjct: 29 HRAKCAPSYLFSCFNGGECVHPA----------FCDCRRFNATGPRCQMVYNAGPERDSI 78
Query: 867 CSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPGTFRILVGN-KGCSHPSVKCKKRV 925
C G H TFDGL Y G+ Y LV + +F I V N C C + V
Sbjct: 79 CRAWGQHHVETFDGLYYYLSGKGSYTLVGRH-EPEGQSFSIQVHNDPQCGSSPYTCSRAV 137
Query: 926 TILVEGGE-----IELFDGEVNVKRPMKDETHFEVVESGR------YIILLLGKALSVVW 974
++ G + E+ G + V+ P V+ S R Y+I+ A ++ W
Sbjct: 138 SLFFVGEQEIHLAKEVTHGGMRVQLP-------HVMGSARLQQLAGYVIVRHQSAFTLAW 190
Query: 975 DRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKVSSQCADT 1034
D ++ + + GLCGN + +DL +S+ ++ +D V+F +SW+ Q +
Sbjct: 191 DGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQ--EQAPNQ 248
Query: 1035 RKVPLDSS---PATCHNNIMKQTMVDSSCRILTSDVFQDCNKLVDPEPYLDVCIYDTCSC 1091
P SS P N V C L F C+ V P P+ C D C
Sbjct: 249 PPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDL--C 306
Query: 1092 ESIGDCACFCDTIAAYAHVCAQHGKVVT-WRT-ATLCPQSCEERNLRENGYECEWRYNSC 1149
+S+GD A +C +A YA CAQ G+ + WRT C C+E+ + YN C
Sbjct: 307 QSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEK---------AFTYNEC 357
Query: 1150 APACQVTCQHPEP--LACPVQCVEGCHAHCPPGKILDELLQTCVDPEDCPVCEVAGRRFA 1207
C +C HP + + CV+GC +CP G I ++ CV P +CP CE G +
Sbjct: 358 IACCPASC-HPRASCVDSEIACVDGC--YCPNGLIFED--GGCVAPAECP-CEFHGTLYP 411
Query: 1208 SGKKVTLNPSDPEHCQICHCDVVNLTCEACQEP 1240
G V E C C C C P
Sbjct: 412 PGSVV------KEDCNTCTCTSGKWECSTAVCP 438
Score = 129 bits (323), Expect = 5e-29
Identities = 101/363 (27%), Positives = 151/363 (41%), Gaps = 58/363 (15%)
Query: 1939 TCGC---RW-----TCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKEQD-LEVILH 1989
TC C +W CP C+ + H TFDG+ + +C Y+L +++ V L
Sbjct: 422 TCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQ 481
Query: 1990 NGACSPGARQGCMKSIEVKHSALSVELHSD----MEVTVNGRL-------VSVPYVGGNM 2038
N C C++S+ SV LH D + +T G + + PY
Sbjct: 482 NAPCGLNQDGACVQSV-------SVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAF 534
Query: 2039 EVNVYGAIMHEVRFNHLGHIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFML 2098
E+ ++ VR N +G + + LQ+ + + T GLCG + N +DF+
Sbjct: 535 EIRRLSSVFLRVRTN-VGVRVLYDREGLRLYLQVDQR-WVEDTVGLCGTFNGNTQDDFLS 592
Query: 2099 RDGTVTTDWKTLVQEWTVQRPGQTCQPILEEQCLVPDSSH----------CQVLLLPLFA 2148
G + + W C P++ L P H C VL +FA
Sbjct: 593 PVGVPESTPQLFGNSWKTL---SACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFA 649
Query: 2149 ECHKVLAPATFYAICQQDSCH--QEQVCEVIASYAHLCRTNGVCVDWRTP-DFCAMSCPP 2205
C L+P ++ C++D+C Q +C +A YAHLCR +G+ VD+R CA+SC
Sbjct: 650 PCSAFLSPVPYFEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEA 709
Query: 2206 SLVYNHCEHGCPRHCDGNVS--SCG---------DHPSEGCFCPPDKVM--LEGSCVPEE 2252
S Y+ C C R C S +CG D EGC CPPD + CVP
Sbjct: 710 SKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRN 769
Query: 2253 ACT 2255
C+
Sbjct: 770 QCS 772
Score = 119 bits (298), Expect = 4e-26
Identities = 103/380 (27%), Positives = 149/380 (39%), Gaps = 50/380 (13%)
Query: 1949 VCTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKE---QDLEVILHNGACSPGARQGCMKSI 2005
+C H+ TFDG + L+G SY L E Q + +HN + C +++
Sbjct: 78 ICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAV 137
Query: 2006 EVKHSALSVELHSDMEVTVNGRLVSVPYVGGNMEVNV---YGAIMHEVRFNHLGHIFTFT 2062
+ E+H EVT G V +P+V G+ + Y + H+ F
Sbjct: 138 SLFFVG-EQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFT------LAW 190
Query: 2063 PQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTVQRPGQ- 2121
+ +++SP+ T+GLCG + + +D + G +T D V W Q P Q
Sbjct: 191 DGASAVYIKMSPELLGW-THGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQP 249
Query: 2122 ---TCQPILEEQCLVPDSS-------HCQVLLLPLFAECHKVLAPATFYAICQQDSCHQ- 2170
T + CL + C+ LL P F CH ++P F A C D C
Sbjct: 250 PGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSM 309
Query: 2171 ---EQVCEVIASYAHLCRTNGVCVD-WRTP-DFCAMSC-PPSLVYNHCEHGCPRHCDGNV 2224
C +A YA C G + WRT C + C + YN C CP C
Sbjct: 310 GDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPR- 368
Query: 2225 SSCGDHP---SEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWVPD----HQP 2277
+SC D +GC+CP + +G CV C C +F P +
Sbjct: 369 ASCVDSEIACVDGCYCPNGLIFEDGGCVAPAEC-PC--------EFHGTLYPPGSVVKED 419
Query: 2278 CQICTCLSGRKVNCTTQPCP 2297
C CTC SG K C+T CP
Sbjct: 420 CNTCTCTSG-KWECSTAVCP 438
Score = 91.3 bits (225), Expect = 1e-17
Identities = 82/333 (24%), Positives = 119/333 (35%), Gaps = 41/333 (12%)
Query: 1888 RPGDVWTLPDQCHTV----TCQPDGQTLLKSHRVNCDRGLRPSCPNSQSPVKVEETCGCR 1943
R GD LP++C P Q + H C RG S + P
Sbjct: 862 RHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRG---SFQCTLHP---------- 908
Query: 1944 WTCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQN-KEQDLEVILHNGACSPGARQGCM 2002
C CT RH TFDG F G+C L ++ + VI+ N C C
Sbjct: 909 --CASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSSGMI-CR 965
Query: 2003 KSIEVKHSALSVELHSDMEVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHLGHIFTFT 2062
K I + + D +G ++ EV+ + + HI
Sbjct: 966 KFISINVGNSLIVFDDD-----SGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLW 1020
Query: 2063 PQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTVQRPGQT 2122
Q +Q P+ + + GLCG D N+ + T+ + W T
Sbjct: 1021 DQRTTVHVQAGPQ-WQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDT 1079
Query: 2123 CQPILEEQCLVPD------SSHCQVLLLPLFAECHKVLAPATFYAICQQDSCHQEQ---- 2172
P + C++ C +LL +F CH V+ FY+ C D+C Q
Sbjct: 1080 LDP--RDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDC 1137
Query: 2173 --VCEVIASYAHLCRTNGVCVDWRTPDFCAMSC 2203
C +++YAH C +GV VDWRTP C C
Sbjct: 1138 ECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDC 1170
Score = 82.8 bits (203), Expect = 4e-15
Identities = 85/360 (23%), Positives = 139/360 (38%), Gaps = 55/360 (15%)
Query: 379 CSNEECPGECLVTGQSHFKSFDNRYFTFSGICQYLLARDCQDHSFSIVIETVQCADDR-- 436
C EC C + F +FD + Y+L++ + + + + C
Sbjct: 2030 CPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDE---MLTVHVLDCKSANLG 2086
Query: 437 ----DAVCTRSVTVRLPGLHNSLVKLKHGAGVAMDGQDVQLPLLKGDLRIQHTVTASVRL 492
C V + + L + + + V +D Q V P+ + RI+ T + L
Sbjct: 2087 HLNWPPFCL--VMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMIL 2144
Query: 493 SYGEDLQMDW-DGRGRLLVKLSPVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVED--- 548
+ D+Q+ W G ++V+ S + GLCG +G+ +D G ED
Sbjct: 2145 T-PSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAP 2203
Query: 549 FGNAWKLHGDCQDLQKQHSDPCALNPRMTRFSEEACA---------VLTSPTFEACHRAV 599
F ++W++ + + TRF ++CA ++++ TF ACHR V
Sbjct: 2204 FLDSWQVPSSLTSVGQ------------TRFRPDSCATTDCSPCLRMVSNRTFSACHRFV 2251
Query: 600 SPLPY----LRNCRYDVCSCSDGRECLCGALASYAAACAGRGVRVAWREPGRCELNCPKG 655
P + +R+ +Y + C AL Y A C V + WR C C
Sbjct: 2252 PPESFCELWIRDTKYV--------QQPCVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSD 2303
Query: 656 QVYLQCGTPCN--LTCRS--LSYPDEECNEACLEGCFCPPGLYMDERGD--CVPKAQCPC 709
Y C T C TC+ L D E + EGC C G + R C+P+A+C C
Sbjct: 2304 STYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCAC 2363
Score = 79.7 bits (195), Expect = 4e-14
Identities = 108/447 (24%), Positives = 164/447 (36%), Gaps = 67/447 (14%)
Query: 798 ECMSMGCVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAPGETVKIGCNTCVCRDRKWN 857
+C+ C+ G L +H + A RC G V++G + C
Sbjct: 1986 DCVRHICLEGQLIRVNQSQHCPQGAAPPRCGIL--------GLAVRVGGDRC-------- 2029
Query: 858 CTDHVCDATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPGTFRIL---VGNKGC 914
C C CS ++TFDG E Y+L Q T +L N G
Sbjct: 2030 CPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS--PDEMLTVHVLDCKSANLGH 2087
Query: 915 SH--PSVKCKKRVTILVEGGEIELFDGEVNVKR----PMKDETHFEVVESGRYIILLLGK 968
+ P +T L I+ F+ +V V P F + ++G ++L
Sbjct: 2088 LNWPPFCLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPS 2147
Query: 969 ALSVVWDRHLSISVV-LKQTYQEKVCGLCGNFDGIQNNDLTSSNLQV---EEDPVDFGNS 1024
+ + W + +V +T + + GLCG DG NDLT + V EDP F +S
Sbjct: 2148 DIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDS 2207
Query: 1025 WKVSSQCADTRKVPLDSSPATCHNNIMKQTMVDSSCRILTSDVFQDCNKLVDPEPYLDVC 1084
W+V S + P +C T R++++ F C++ V PE + ++
Sbjct: 2208 WQVPSSLTSVGQTRF--RPDSCAT-----TDCSPCLRMVSNRTFSACHRFVPPESFCELW 2260
Query: 1085 IYDTCSCESIGDCACFCDTIAAYAHVCAQHGKVVTWRTATLCPQSCEERNLRENGYECEW 1144
I DT + C + Y +C + + WR + CP C +
Sbjct: 2261 IRDTKYVQQP------CVALTVYVAMCHKFHVCIEWRRSDYCPFLCSS----------DS 2304
Query: 1145 RYNSCAPACQ--VTCQHP-----EPLACPVQCVEGCHAHCPPGKILDELLQT-CVDPEDC 1196
Y +C AC+ TCQ +P C V EGC C G IL C+ C
Sbjct: 2305 TYQACVTACEPPKTCQDGILGPLDPEHCQV-LGEGC--VCSEGTILHRRHSALCIPEAKC 2361
Query: 1197 PVCEVAGRRFASGKKVTLNPSDPEHCQ 1223
+ G A G+ T N S CQ
Sbjct: 2362 ACTDSMGVPRALGE--TWNSSLSGCCQ 2386
Score = 74.7 bits (182), Expect = 1e-12
Identities = 89/366 (24%), Positives = 137/366 (37%), Gaps = 38/366 (10%)
Query: 10 LLALALILPGTLCAEGTRGRSSTARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRS 69
+L LA+ + G C RCS+F TFDGS + Y+L+ +
Sbjct: 2017 ILGLAVRVGGDRCCPLWE---CACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEML 2073
Query: 70 FSIIGDFQNGKRVSLS-----------VYLGEFFDIHLFVNGTVTQGDQRVSMPYASKGL 118
+ D ++ L+ +L I F N VT Q V P + G
Sbjct: 2074 TVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRF-NRKVTVDLQPVWPPVSRYGF 2132
Query: 119 YLETEAGYYKLSGEAYGFVARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEG 178
+E Y + + + + SG V S + GLCG + A +D ++G
Sbjct: 2133 RIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDG 2192
Query: 179 TLTS---DPYDFANSWALSSGEQWCERASPPSSSCNISSGEMQKGLWEQCQLLKSTSVFA 235
++ DP F +SW + S + SC + C + S F+
Sbjct: 2193 SVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTD-------CSPCLRMVSNRTFS 2245
Query: 236 RCHPLVDPEPFVALCEKTLCECAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVC 295
CH V PE F CE + + ++ C AL Y C + V W C +C
Sbjct: 2246 ACHRFVPPESF---CELWIRD-TKYVQQPCVALTVYVAMC-HKFHVCIEWRRSDYCPFLC 2300
Query: 296 PAGMEYRQCVSPC--ARTCQSLHINEMCQERCV---DGCSCPEGQLL---DEGLCVESTE 347
+ Y+ CV+ C +TCQ + + E C +GC C EG +L LC+ +
Sbjct: 2301 SSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAK 2360
Query: 348 CPCVHS 353
C C S
Sbjct: 2361 CACTDS 2366
Score = 62.4 bits (150), Expect = 6e-09
Identities = 28/56 (50%), Positives = 35/56 (62%), Gaps = 1/56 (1%)
Query: 1142 CEWRYNSCAPACQVTCQHPEPLAC-PVQCVEGCHAHCPPGKILDELLQTCVDPEDC 1196
CEWRY++CA C TC+ P +C V VEGC CP ++LDE+ Q CV EDC
Sbjct: 1336 CEWRYDACASPCFQTCRDPRAASCRDVPRVEGCVPVCPTPQVLDEVTQRCVYLEDC 1391
Score = 45.4 bits (106), Expect = 8e-04
Identities = 53/200 (26%), Positives = 73/200 (36%), Gaps = 50/200 (25%)
Query: 2342 RGLQPTLTNPGECRPNFTCACRKE-----ECKRVSPPSCPPHRLPTLRKTQCCD-EYECA 2395
R LQ T +C T C+++ EC P SC P + C D E C
Sbjct: 331 RPLQGWRTQLRQC----TVHCKEKAFTYNECIACCPASCHP-------RASCVDSEIACV 379
Query: 2396 CNCVNSTVSCPLGYLASTATNDCGCTTTTCLPDKVCVHRSTIYPVGQFWEEGCDVCTCTD 2455
C CP G + D GC P C T+YP G +E C+ CTCT
Sbjct: 380 DGCY-----CPNGLIFE----DGGCVAPAECP---CEFHGTLYPPGSVVKEDCNTCTCTS 427
Query: 2456 MEDAVMGLRVAQCSQKPCEDSCRSGFTYVLHEGECCGR--CLPSACEVVTGSPRGDSQSS 2513
+ +CS C C T +H GR P+ C+ + R
Sbjct: 428 GK--------WECSTAVCPAEC--SVTGDIHFTTFDGRRYTFPATCQYILAKSR------ 471
Query: 2514 WKSVGSQWASPEN-PCLINE 2532
S G+ + +N PC +N+
Sbjct: 472 --SSGTFTVTLQNAPCGLNQ 489
Score = 34.7 bits (78), Expect = 1.4
Identities = 22/63 (34%), Positives = 28/63 (44%), Gaps = 6/63 (9%)
Query: 290 ACSPVCPAGMEYRQCVSPCARTCQSLHINEMCQERCVDGC--SCPEGQLLDE--GLCVES 345
A P+C Y C SPC +TC+ V+GC CP Q+LDE CV
Sbjct: 1331 AAYPICE--WRYDACASPCFQTCRDPRAASCRDVPRVEGCVPVCPTPQVLDEVTQRCVYL 1388
Query: 346 TEC 348
+C
Sbjct: 1389 EDC 1391
>gi|239744298 PREDICTED: otogelin isoform 1 [Homo sapiens]
Length = 2924
Score = 654 bits (1688), Expect = 0.0
Identities = 393/1135 (34%), Positives = 560/1135 (49%), Gaps = 80/1135 (7%)
Query: 35 CSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRSFSIIGDFQNGKRVSLSVY-----LG 89
C +G V TFDG Y +G SY L G + S N + S Y +
Sbjct: 151 CRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVS 210
Query: 90 EFF----DIHLFVNGTVTQGDQRVSMPYASKGLYLETEAGYYKLSGEAYGFVARIDGSGN 145
FF +IHL VT G RV +P+ L+ AGY + ++ F DG+
Sbjct: 211 LFFVGEQEIHLAKE--VTHGGMRVQLPHVMGSARLQQLAGYVIVRHQS-AFTLAWDGASA 267
Query: 146 FQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGEQ--WCERA 203
+ +S T GLCGN N +DD +T G LT D +F +SW + Q +
Sbjct: 268 VYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTS 327
Query: 204 SPPSSSCNISSGEMQKGLWEQCQLLKSTSVFARCHPLVDPEPFVALCEKTLCECAGGLEC 263
S P C + +G++EQC+ L F CH V P PF A C LC+ G +
Sbjct: 328 SLPRPPCLQQNPGTMQGVYEQCEALLRPP-FDACHAYVSPLPFTASCTSDLCQSMGDVAT 386
Query: 264 ACPALLEYARTCAQEGMVLYGW-TDHSACSPVCPA-GMEYRQCVSPCARTCQSLHINEMC 321
C AL EYAR CAQ G L GW T C+ C Y +C++ C +C H C
Sbjct: 387 WCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASC---HPRASC 443
Query: 322 QER---CVDGCSCPEGQLLDEGLCVESTECPCVHSGKRYPPGTSLSRDCNTCICRNSQWI 378
+ CVDGC CP G + ++G CV ECPC G YPPG+ + DCNTC C + +W
Sbjct: 444 VDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWE 503
Query: 379 CSNEECPGECLVTGQSHFKSFDNRYFTFSGICQYLLARDCQDHSFSIVIETVQCADDRDA 438
CS CP EC VTG HF +FD R +TF CQY+LA+ +F++ ++ C ++D
Sbjct: 504 CSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDG 563
Query: 439 VCTRSVTVRLPGLHNSLVKLKHGAGVAMDGQDVQLPLLKGD---LRIQHTVTASVRLSYG 495
C +SV+V L V L V + Q +P D +R +V VR + G
Sbjct: 564 ACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVG 623
Query: 496 EDLQMDWDGRGRLLVKLSPVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWKL 555
+ D +G RL +++ + T GLCG +NGN DDFL+P G+ E + FGN+WK
Sbjct: 624 VRVLYDREGL-RLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKT 682
Query: 556 HGDCQDL-QKQHSDPCALNPRMTRFSEEACAVLTSPTFEACHRAVSPLPYLRNCRYDVCS 614
C L DPC ++ + +S +AC+VLT F C +SP+PY CR D C
Sbjct: 683 LSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACR 742
Query: 615 CSDGRECLCGALASYAAACAGRGVRVAWR-EPGRCELNCPKGQVYLQCGTPCNLTCRSLS 673
C G+ CLC LA YA C G+ V +R C L+C + Y C PC TC+ L+
Sbjct: 743 C--GQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLA 800
Query: 674 YP--------DEECNEACLEGCFCPPGLYMDERGD-CVPKAQCPCYYDGEIFQPEDIFSD 724
P D+ + C+EGC CPP Y+D + D CVP+ QC C++ G + P D
Sbjct: 801 SPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIP 860
Query: 725 HHTMCYCEDGFMHCTMSGVPGSLLPDAVLSSPLSHRSKRSLSCRPPMVKLVCPADNLRAE 784
C+C+DG M C S P + +C V + C + E
Sbjct: 861 SLGHCHCKDGVMSCD-SRAPAA-------------------ACPAGQVFVNCSDLHTDLE 900
Query: 785 GLECTKTC--QNYDLECMSMG-CVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAPGET 841
L +TC Q +L + G C+SGC CP G++RH + C E CPC +GKEY PG+
Sbjct: 901 -LSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQ 959
Query: 842 VKIGCNTCVCRDRKWNCTDHVCDATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSN 901
V C+TCVC+ + CT H C +TC+ G HY TFDGL + F G C+ LV+ ++
Sbjct: 960 VMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVK---STS 1016
Query: 902 PGTFRILVGNKGCSHPSVKCKKRVTILVEGGEIELFDGEVNVKRP---MKDETHFEVVES 958
+F ++V N C + C+K ++I V G + +FD + P + D+
Sbjct: 1017 DVSFSVIVENVNCYSSGMICRKFISINV-GNSLIVFDDDSGNPSPESFLDDKQEVHTWRV 1075
Query: 959 GRYIILLLGKA-LSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDL-TSSNLQVEE 1016
G + ++ + ++++WD+ ++ V +Q ++ GLCGNFD N++ T NL++
Sbjct: 1076 GFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLEL-T 1134
Query: 1017 DPVDFGNSWKVSSQCADTRKVPLDSSPATCHNNIMKQTMVDSSCRILTSDVFQDCNKLVD 1076
+P +FG+SW + +C DT P D C N +++ C IL S+VF+ C+ +VD
Sbjct: 1135 NPQEFGSSW-AAVECPDTLD-PRD----MCVLNPLREPFAKKECSILLSEVFEICHPVVD 1188
Query: 1077 PEPYLDVCIYDTCSCESIGDCACFCDTIAAYAHVCAQHGKVVTWRTATLCPQSCE 1131
+ C+ DTC C GDC CFC +++AYAH C QHG V WRT LCP C+
Sbjct: 1189 VTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDCD 1243
Score = 240 bits (612), Expect = 2e-62
Identities = 232/952 (24%), Positives = 362/952 (38%), Gaps = 148/952 (15%)
Query: 1907 DGQTLLKSHRVNCDRGLRPS-CPNSQSPVKVE-ETCGCRWTCPCVCTGSSTRHIVTFDGQ 1964
+GQ + + +C +G P C V+V + C W C C C+ VTFDG
Sbjct: 2066 EGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGS 2125
Query: 1965 NFKLTGSCSYVLFQNKEQDLEV-ILHNGACSPGARQG---CMKSIEVKHSALSVELHS-D 2019
+ L Y+L Q+ ++ L V +L + + G C+ + + H A V + +
Sbjct: 2126 HVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFN 2185
Query: 2020 MEVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHLGHIFTF-TPQNNEFQ--------L 2070
+VTV+ + V P V+ YG R GH++ TP + + Q +
Sbjct: 2186 RKVTVDLQPVWPP-------VSRYG-----FRIEDTGHMYMILTPSDIQIQWLHSSGLMI 2233
Query: 2071 QLSPKTFASKTYGLCGICDENGANDFMLRDGTVT---TDWKTLVQEWTVQRP----GQTC 2123
+ KT ++ +GLCGICD + AND L+DG+V D + W V GQT
Sbjct: 2234 VEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQT- 2292
Query: 2124 QPILEEQCLVPDSSHC-QVLLLPLFAECHKVLAPATFYAICQQDSCHQEQVCEVIASYAH 2182
+ C D S C +++ F+ CH+ + P +F + +D+ + +Q C + Y
Sbjct: 2293 -RFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVA 2351
Query: 2183 LCRTNGVCVDWRTPDFCAMSCPPSLVYNHCEHGC--PRHCDGNVSSCGDHP-----SEGC 2235
+C VC++WR D+C C Y C C P+ C + D EGC
Sbjct: 2352 MCHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGC 2411
Query: 2236 FCPPDKVMLE---GSCVPEEACTQCIGEDGVQHQFLEAWVPDHQPCQICTCLSGRKVNCT 2292
C ++ C+PE C C GV E W C C + +
Sbjct: 2412 VCSEGTILHRRHSALCIPEAKCA-CTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPV 2470
Query: 2293 TQPCPTAKAPTC-GLCEVARLRQNADQCCPEYECVCDPVSCDLPPVPHCERGLQP-TLTN 2350
CP+ + +C EVA L D CC CVC+ C+ P C G + T
Sbjct: 2471 DLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCE-GLAPTCRPGHRLLTHFQ 2529
Query: 2351 PGECRPNFTCACRKEECKRVSPPSCPPHRLPTLRKT--QCCDEYECAC-NCVNSTVSCPL 2407
C P+++C C + C+ PSC ++ + CC Y CAC +C +S C
Sbjct: 2530 EDSCCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQE 2589
Query: 2408 GYLASTATNDCGCTTTTCLPDKVCVHRSTIYPVGQFWEEGCDVCTCTDMEDAVMGLRVAQ 2467
G + + VHR+T ++ C C + +
Sbjct: 2590 G-------------------EALTVHRNTTELCCPLYQ-----CVCENF----------R 2615
Query: 2468 CSQKPCEDSCRSGFTYVLHEGECCGRCLP-SACEVVTGSPRGDSQSSWKSVGSQWASPEN 2526
C Q C G L E RC P +CE + P
Sbjct: 2616 CPQVQC------GLGTALVEVWSPDRCCPYKSCECDCDT-----------------IPVP 2652
Query: 2527 PCLINECVRVKEEVFIQQRNVSCPQLEVPVCPSGFQLSCKTSACCPSCRCERMEACMLNG 2586
C + E ++ EE F S + C C + C+
Sbjct: 2653 RCHLWEKSQLDEE---------------------FMHSVENVCGCAKYECVKAPVCLSRE 2691
Query: 2587 T-VIGPGKTVMI----DVCTTCRCMVQVGVISGF-KLECRKTTCN-PCPLG--YKEENNT 2637
V+ PG+TV+ VC T RC + ++ F ++ C+ C Y+ +
Sbjct: 2692 LGVMQPGQTVVELSADGVCHTSRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDL 2751
Query: 2638 GECCGRCLPTACTIQLRGGQIMTLKRDETLQDGCDTHFCKVNERGEYFWEKRVTGCPPFD 2697
CCG C +C G + C H C G ++ CPP +
Sbjct: 2752 AACCGSCRNVSCLFTFPNGTTSLFLPGASWIADCARHHCSSTPLGAVLVRSPIS-CPPLN 2810
Query: 2698 EHKCLAEGGKIMKIPGTCCDTCEEP--ECNDITARLQYVKVGSCKSEVEVDIHYCQGKCA 2755
E +C GG ++ CC TC+E C +T R+ ++ C+S V++ C G+C
Sbjct: 2811 ETECAKVGGSVVPSLEGCCRTCKEDGRSCKKVTIRMT-IRKNECRSSTPVNLVSCDGRCP 2869
Query: 2756 SKAMYSIDINDVQDQCSCCSPTRTEPMQVALHC-TNGSVVYHEVLNAMECKC 2806
S ++Y+ +IN C CC + V L C TN + V + V +C C
Sbjct: 2870 SASIYNYNINTYARFCKCCREVGLQRRSVQLFCATNATWVPYTVQEPTDCAC 2921
Score = 233 bits (594), Expect = 2e-60
Identities = 150/461 (32%), Positives = 207/461 (44%), Gaps = 58/461 (12%)
Query: 802 MGCVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAPGETVKIGCNTCVCRDRKWNCTDH 861
+ CV GC CP G++ + CVA CPC G Y PG VK CNTC C KW C+
Sbjct: 448 IACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWECSTA 507
Query: 862 VCDATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPGTFRILVGNKGCS-HPSVK 920
VC A CS G H+ TFDG +Y FP CQY+L + + GTF + + N C +
Sbjct: 508 VCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKS---RSSGTFTVTLQNAPCGLNQDGA 564
Query: 921 CKKRVTI-----------LVEGGEIELFDGEVNVKRPMKDETHFEVVE-SGRYIILLLGK 968
C + V++ L + G++ LFD + + P D+ FE+ S ++ +
Sbjct: 565 CVQSVSVILHQDPRRQVTLTQAGDVLLFD-QYKIIPPYTDDA-FEIRRLSSVFLRVRTNV 622
Query: 969 ALSVVWDRH-LSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKV 1027
+ V++DR L + + + Q + E GLCG F+G +D S E P FGNSWK
Sbjct: 623 GVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKT 682
Query: 1028 SSQCAD-TRKVPLDSSPATCHNNIMKQTMVDSSCRILTSDVFQDCNKLVDPEPYLDVCIY 1086
S C+ PLD C ++ + +C +LT ++F C+ + P PY + C
Sbjct: 683 LSACSPLVSGSPLDP----CDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRR 738
Query: 1087 DTCSCESIGDCACFCDTIAAYAHVCAQHGKVVTWRTAT-LCPQSCEERNLRENGYECEWR 1145
D C C C C T+A YAH+C +HG V +R C SCE
Sbjct: 739 DACRCGQ----PCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASK----------E 784
Query: 1146 YNSCAPACQVTCQH-PEPLACPV---------QCVEGCHAHCPPGKILDELLQTCVDPED 1195
Y+ C C TCQ P AC V +CVEGC CPP LD CV
Sbjct: 785 YSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCA--CPPDTYLDTQADLCVPRNQ 842
Query: 1196 CPVCEVAGRRFASGKKVTLNPSDPEHCQICHCDVVNLTCEA 1236
C C G + G SD CHC ++C++
Sbjct: 843 CS-CHFQGVDYPPG------DSDIPSLGHCHCKDGVMSCDS 876
Score = 157 bits (396), Expect = 2e-37
Identities = 110/380 (28%), Positives = 157/380 (41%), Gaps = 31/380 (8%)
Query: 33 ARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRSFSI------IGDFQNG---KRVS 83
A CS+ G TFDG Y+F C Y+LA +F++ G Q+G + VS
Sbjct: 511 AECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVS 570
Query: 84 LSVYLGEFFDIHLFVNGTVTQGDQ-RVSMPYASKGLYLETEAGYYKLSGEAYGFVARIDG 142
+ ++ + L G V DQ ++ PY + + + G D
Sbjct: 571 VILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDR 630
Query: 143 SG-NFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGEQWCE 201
G + + R+ T GLCG FN +DDF++ G S P F NSW S C
Sbjct: 631 EGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSA---CS 687
Query: 202 R--ASPPSSSCNISSGEMQKGLWEQCQLLKSTSVFARCHPLVDPEPFVALCEKTLCECAG 259
+ P C++ + + C +L + +FA C + P P+ C + C C
Sbjct: 688 PLVSGSPLDPCDVHLQAASYSV-QACSVL-TGEMFAPCSAFLSPVPYFEQCRRDACRC-- 743
Query: 260 GLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCARTCQSLHINE 319
G C C L YA C + G+ + AC+ C A EY CV+PC RTCQ L E
Sbjct: 744 GQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPE 803
Query: 320 MC---------QERCVDGCSCPEGQLLD--EGLCVESTECPCVHSGKRYPPGTSLSRDCN 368
C ++ CV+GC+CP LD LCV +C C G YPPG S
Sbjct: 804 ACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLG 863
Query: 369 TCICRNSQWICSNEECPGEC 388
C C++ C + C
Sbjct: 864 HCHCKDGVMSCDSRAPAAAC 883
Score = 136 bits (342), Expect = 3e-31
Identities = 124/453 (27%), Positives = 180/453 (39%), Gaps = 72/453 (15%)
Query: 817 HENRCVALERCPCFHQGKEYAPGETVKIGCNTCVCRDRKWNCTDHVC----------DAT 866
H +C CF+ G+ P C R++N T C D+
Sbjct: 101 HRAKCAPSYLFSCFNGGECVHPA----------FCDCRRFNATGPRCQMVYNAGPERDSI 150
Query: 867 CSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPGTFRILVGN-KGCSHPSVKCKKRV 925
C G H TFDGL Y G+ Y LV + +F I V N C C + V
Sbjct: 151 CRAWGQHHVETFDGLYYYLSGKGSYTLVGRH-EPEGQSFSIQVHNDPQCGSSPYTCSRAV 209
Query: 926 TILVEGGE-----IELFDGEVNVKRPMKDETHFEVVESGR------YIILLLGKALSVVW 974
++ G + E+ G + V+ P V+ S R Y+I+ A ++ W
Sbjct: 210 SLFFVGEQEIHLAKEVTHGGMRVQLP-------HVMGSARLQQLAGYVIVRHQSAFTLAW 262
Query: 975 DRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKVSSQCADT 1034
D ++ + + GLCGN + +DL +S+ ++ +D V+F +SW+ Q +
Sbjct: 263 DGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQ--EQAPNQ 320
Query: 1035 RKVPLDSS---PATCHNNIMKQTMVDSSCRILTSDVFQDCNKLVDPEPYLDVCIYDTCSC 1091
P SS P N V C L F C+ V P P+ C D C
Sbjct: 321 PPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDL--C 378
Query: 1092 ESIGDCACFCDTIAAYAHVCAQHGKVVT-WRT-ATLCPQSCEERNLRENGYECEWRYNSC 1149
+S+GD A +C +A YA CAQ G+ + WRT C C+E+ + YN C
Sbjct: 379 QSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEK---------AFTYNEC 429
Query: 1150 APACQVTCQHPEP--LACPVQCVEGCHAHCPPGKILDELLQTCVDPEDCPVCEVAGRRFA 1207
C +C HP + + CV+GC +CP G I ++ CV P +CP CE G +
Sbjct: 430 IACCPASC-HPRASCVDSEIACVDGC--YCPNGLIFED--GGCVAPAECP-CEFHGTLYP 483
Query: 1208 SGKKVTLNPSDPEHCQICHCDVVNLTCEACQEP 1240
G V E C C C C P
Sbjct: 484 PGSVV------KEDCNTCTCTSGKWECSTAVCP 510
Score = 129 bits (323), Expect = 5e-29
Identities = 101/363 (27%), Positives = 151/363 (41%), Gaps = 58/363 (15%)
Query: 1939 TCGC---RW-----TCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKEQD-LEVILH 1989
TC C +W CP C+ + H TFDG+ + +C Y+L +++ V L
Sbjct: 494 TCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQ 553
Query: 1990 NGACSPGARQGCMKSIEVKHSALSVELHSD----MEVTVNGRL-------VSVPYVGGNM 2038
N C C++S+ SV LH D + +T G + + PY
Sbjct: 554 NAPCGLNQDGACVQSV-------SVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAF 606
Query: 2039 EVNVYGAIMHEVRFNHLGHIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFML 2098
E+ ++ VR N +G + + LQ+ + + T GLCG + N +DF+
Sbjct: 607 EIRRLSSVFLRVRTN-VGVRVLYDREGLRLYLQVDQR-WVEDTVGLCGTFNGNTQDDFLS 664
Query: 2099 RDGTVTTDWKTLVQEWTVQRPGQTCQPILEEQCLVPDSSH----------CQVLLLPLFA 2148
G + + W C P++ L P H C VL +FA
Sbjct: 665 PVGVPESTPQLFGNSWKTL---SACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFA 721
Query: 2149 ECHKVLAPATFYAICQQDSCH--QEQVCEVIASYAHLCRTNGVCVDWRTP-DFCAMSCPP 2205
C L+P ++ C++D+C Q +C +A YAHLCR +G+ VD+R CA+SC
Sbjct: 722 PCSAFLSPVPYFEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEA 781
Query: 2206 SLVYNHCEHGCPRHCDGNVS--SCG---------DHPSEGCFCPPDKVM--LEGSCVPEE 2252
S Y+ C C R C S +CG D EGC CPPD + CVP
Sbjct: 782 SKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRN 841
Query: 2253 ACT 2255
C+
Sbjct: 842 QCS 844
Score = 119 bits (298), Expect = 4e-26
Identities = 103/380 (27%), Positives = 149/380 (39%), Gaps = 50/380 (13%)
Query: 1949 VCTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKE---QDLEVILHNGACSPGARQGCMKSI 2005
+C H+ TFDG + L+G SY L E Q + +HN + C +++
Sbjct: 150 ICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAV 209
Query: 2006 EVKHSALSVELHSDMEVTVNGRLVSVPYVGGNMEVNV---YGAIMHEVRFNHLGHIFTFT 2062
+ E+H EVT G V +P+V G+ + Y + H+ F
Sbjct: 210 SLFFVG-EQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFT------LAW 262
Query: 2063 PQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTVQRPGQ- 2121
+ +++SP+ T+GLCG + + +D + G +T D V W Q P Q
Sbjct: 263 DGASAVYIKMSPELLGW-THGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQP 321
Query: 2122 ---TCQPILEEQCLVPDSS-------HCQVLLLPLFAECHKVLAPATFYAICQQDSCHQ- 2170
T + CL + C+ LL P F CH ++P F A C D C
Sbjct: 322 PGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSM 381
Query: 2171 ---EQVCEVIASYAHLCRTNGVCVD-WRTP-DFCAMSC-PPSLVYNHCEHGCPRHCDGNV 2224
C +A YA C G + WRT C + C + YN C CP C
Sbjct: 382 GDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPR- 440
Query: 2225 SSCGDHP---SEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWVPD----HQP 2277
+SC D +GC+CP + +G CV C C +F P +
Sbjct: 441 ASCVDSEIACVDGCYCPNGLIFEDGGCVAPAEC-PC--------EFHGTLYPPGSVVKED 491
Query: 2278 CQICTCLSGRKVNCTTQPCP 2297
C CTC SG K C+T CP
Sbjct: 492 CNTCTCTSG-KWECSTAVCP 510
Score = 91.3 bits (225), Expect = 1e-17
Identities = 82/333 (24%), Positives = 119/333 (35%), Gaps = 41/333 (12%)
Query: 1888 RPGDVWTLPDQCHTV----TCQPDGQTLLKSHRVNCDRGLRPSCPNSQSPVKVEETCGCR 1943
R GD LP++C P Q + H C RG S + P
Sbjct: 934 RHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRG---SFQCTLHP---------- 980
Query: 1944 WTCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQN-KEQDLEVILHNGACSPGARQGCM 2002
C CT RH TFDG F G+C L ++ + VI+ N C C
Sbjct: 981 --CASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSSGMI-CR 1037
Query: 2003 KSIEVKHSALSVELHSDMEVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHLGHIFTFT 2062
K I + + D +G ++ EV+ + + HI
Sbjct: 1038 KFISINVGNSLIVFDDD-----SGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLW 1092
Query: 2063 PQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTVQRPGQT 2122
Q +Q P+ + + GLCG D N+ + T+ + W T
Sbjct: 1093 DQRTTVHVQAGPQ-WQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDT 1151
Query: 2123 CQPILEEQCLVPD------SSHCQVLLLPLFAECHKVLAPATFYAICQQDSCHQEQ---- 2172
P + C++ C +LL +F CH V+ FY+ C D+C Q
Sbjct: 1152 LDP--RDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDC 1209
Query: 2173 --VCEVIASYAHLCRTNGVCVDWRTPDFCAMSC 2203
C +++YAH C +GV VDWRTP C C
Sbjct: 1210 ECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDC 1242
Score = 82.8 bits (203), Expect = 4e-15
Identities = 85/360 (23%), Positives = 139/360 (38%), Gaps = 55/360 (15%)
Query: 379 CSNEECPGECLVTGQSHFKSFDNRYFTFSGICQYLLARDCQDHSFSIVIETVQCADDR-- 436
C EC C + F +FD + Y+L++ + + + + C
Sbjct: 2102 CPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDE---MLTVHVLDCKSANLG 2158
Query: 437 ----DAVCTRSVTVRLPGLHNSLVKLKHGAGVAMDGQDVQLPLLKGDLRIQHTVTASVRL 492
C V + + L + + + V +D Q V P+ + RI+ T + L
Sbjct: 2159 HLNWPPFCL--VMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMIL 2216
Query: 493 SYGEDLQMDW-DGRGRLLVKLSPVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVED--- 548
+ D+Q+ W G ++V+ S + GLCG +G+ +D G ED
Sbjct: 2217 T-PSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAP 2275
Query: 549 FGNAWKLHGDCQDLQKQHSDPCALNPRMTRFSEEACA---------VLTSPTFEACHRAV 599
F ++W++ + + TRF ++CA ++++ TF ACHR V
Sbjct: 2276 FLDSWQVPSSLTSVGQ------------TRFRPDSCATTDCSPCLRMVSNRTFSACHRFV 2323
Query: 600 SPLPY----LRNCRYDVCSCSDGRECLCGALASYAAACAGRGVRVAWREPGRCELNCPKG 655
P + +R+ +Y + C AL Y A C V + WR C C
Sbjct: 2324 PPESFCELWIRDTKYV--------QQPCVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSD 2375
Query: 656 QVYLQCGTPCN--LTCRS--LSYPDEECNEACLEGCFCPPGLYMDERGD--CVPKAQCPC 709
Y C T C TC+ L D E + EGC C G + R C+P+A+C C
Sbjct: 2376 STYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCAC 2435
Score = 79.7 bits (195), Expect = 4e-14
Identities = 108/447 (24%), Positives = 164/447 (36%), Gaps = 67/447 (14%)
Query: 798 ECMSMGCVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAPGETVKIGCNTCVCRDRKWN 857
+C+ C+ G L +H + A RC G V++G + C
Sbjct: 2058 DCVRHICLEGQLIRVNQSQHCPQGAAPPRCGIL--------GLAVRVGGDRC-------- 2101
Query: 858 CTDHVCDATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPGTFRIL---VGNKGC 914
C C CS ++TFDG E Y+L Q T +L N G
Sbjct: 2102 CPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS--PDEMLTVHVLDCKSANLGH 2159
Query: 915 SH--PSVKCKKRVTILVEGGEIELFDGEVNVKR----PMKDETHFEVVESGRYIILLLGK 968
+ P +T L I+ F+ +V V P F + ++G ++L
Sbjct: 2160 LNWPPFCLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPS 2219
Query: 969 ALSVVWDRHLSISVV-LKQTYQEKVCGLCGNFDGIQNNDLTSSNLQV---EEDPVDFGNS 1024
+ + W + +V +T + + GLCG DG NDLT + V EDP F +S
Sbjct: 2220 DIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDS 2279
Query: 1025 WKVSSQCADTRKVPLDSSPATCHNNIMKQTMVDSSCRILTSDVFQDCNKLVDPEPYLDVC 1084
W+V S + P +C T R++++ F C++ V PE + ++
Sbjct: 2280 WQVPSSLTSVGQTRF--RPDSCAT-----TDCSPCLRMVSNRTFSACHRFVPPESFCELW 2332
Query: 1085 IYDTCSCESIGDCACFCDTIAAYAHVCAQHGKVVTWRTATLCPQSCEERNLRENGYECEW 1144
I DT + C + Y +C + + WR + CP C +
Sbjct: 2333 IRDTKYVQQP------CVALTVYVAMCHKFHVCIEWRRSDYCPFLCSS----------DS 2376
Query: 1145 RYNSCAPACQ--VTCQHP-----EPLACPVQCVEGCHAHCPPGKILDELLQT-CVDPEDC 1196
Y +C AC+ TCQ +P C V EGC C G IL C+ C
Sbjct: 2377 TYQACVTACEPPKTCQDGILGPLDPEHCQV-LGEGC--VCSEGTILHRRHSALCIPEAKC 2433
Query: 1197 PVCEVAGRRFASGKKVTLNPSDPEHCQ 1223
+ G A G+ T N S CQ
Sbjct: 2434 ACTDSMGVPRALGE--TWNSSLSGCCQ 2458
Score = 74.7 bits (182), Expect = 1e-12
Identities = 89/366 (24%), Positives = 137/366 (37%), Gaps = 38/366 (10%)
Query: 10 LLALALILPGTLCAEGTRGRSSTARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRS 69
+L LA+ + G C RCS+F TFDGS + Y+L+ +
Sbjct: 2089 ILGLAVRVGGDRCCPLWE---CACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEML 2145
Query: 70 FSIIGDFQNGKRVSLS-----------VYLGEFFDIHLFVNGTVTQGDQRVSMPYASKGL 118
+ D ++ L+ +L I F N VT Q V P + G
Sbjct: 2146 TVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRF-NRKVTVDLQPVWPPVSRYGF 2204
Query: 119 YLETEAGYYKLSGEAYGFVARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEG 178
+E Y + + + + SG V S + GLCG + A +D ++G
Sbjct: 2205 RIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDG 2264
Query: 179 TLTS---DPYDFANSWALSSGEQWCERASPPSSSCNISSGEMQKGLWEQCQLLKSTSVFA 235
++ DP F +SW + S + SC + C + S F+
Sbjct: 2265 SVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTD-------CSPCLRMVSNRTFS 2317
Query: 236 RCHPLVDPEPFVALCEKTLCECAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVC 295
CH V PE F CE + + ++ C AL Y C + V W C +C
Sbjct: 2318 ACHRFVPPESF---CELWIRD-TKYVQQPCVALTVYVAMC-HKFHVCIEWRRSDYCPFLC 2372
Query: 296 PAGMEYRQCVSPC--ARTCQSLHINEMCQERCV---DGCSCPEGQLL---DEGLCVESTE 347
+ Y+ CV+ C +TCQ + + E C +GC C EG +L LC+ +
Sbjct: 2373 SSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAK 2432
Query: 348 CPCVHS 353
C C S
Sbjct: 2433 CACTDS 2438
Score = 55.5 bits (132), Expect = 7e-07
Identities = 25/56 (44%), Positives = 32/56 (57%), Gaps = 1/56 (1%)
Query: 1142 CEWRYNSCAPACQVTCQHPEPLAC-PVQCVEGCHAHCPPGKILDELLQTCVDPEDC 1196
CEWRY++CA C TC+ P +C V C CP ++LDE+ Q CV EDC
Sbjct: 1408 CEWRYDACASPCFQTCRDPRAASCRDVPRGRSCVPVCPTPQVLDEVTQRCVYLEDC 1463
Score = 45.4 bits (106), Expect = 8e-04
Identities = 53/200 (26%), Positives = 73/200 (36%), Gaps = 50/200 (25%)
Query: 2342 RGLQPTLTNPGECRPNFTCACRKE-----ECKRVSPPSCPPHRLPTLRKTQCCD-EYECA 2395
R LQ T +C T C+++ EC P SC P + C D E C
Sbjct: 403 RPLQGWRTQLRQC----TVHCKEKAFTYNECIACCPASCHP-------RASCVDSEIACV 451
Query: 2396 CNCVNSTVSCPLGYLASTATNDCGCTTTTCLPDKVCVHRSTIYPVGQFWEEGCDVCTCTD 2455
C CP G + D GC P C T+YP G +E C+ CTCT
Sbjct: 452 DGCY-----CPNGLIFE----DGGCVAPAECP---CEFHGTLYPPGSVVKEDCNTCTCTS 499
Query: 2456 MEDAVMGLRVAQCSQKPCEDSCRSGFTYVLHEGECCGR--CLPSACEVVTGSPRGDSQSS 2513
+ +CS C C T +H GR P+ C+ + R
Sbjct: 500 GK--------WECSTAVCPAEC--SVTGDIHFTTFDGRRYTFPATCQYILAKSR------ 543
Query: 2514 WKSVGSQWASPEN-PCLINE 2532
S G+ + +N PC +N+
Sbjct: 544 --SSGTFTVTLQNAPCGLNQ 561
>gi|134031945 SCO-spondin [Homo sapiens]
Length = 5147
Score = 625 bits (1611), Expect = e-178
Identities = 398/1266 (31%), Positives = 569/1266 (44%), Gaps = 132/1266 (10%)
Query: 12 ALALILPGTLCAEGTRGRSSTARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRSFS 71
AL L G + ++ + +A C+ + TFDG Y F G C+YLLAG
Sbjct: 172 ALLQPLAGAVGQLWSQHQRPSATCASWSGFHYRTFDGRHYHFLGRCTYLLAGAADSTWAV 231
Query: 72 II--GDFQNGKRVSLSVYLGEFFDIHLFVNGTVTQGDQRV--SMPYASKGLYLETEAGYY 127
+ GD V +G + L G V+ Q V + GL L+ +
Sbjct: 232 HLTPGDRCPQPGHCQRVTMGP--EEVLIQAGNVSVKGQLVPEGQSWLLHGLSLQWLGDWL 289
Query: 128 KLSGEAYGFVARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDF 187
LSG G V R+D +G+ + + + +T GLCG +N + EDDFM G L F
Sbjct: 290 VLSG-GLGVVVRLDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATF 348
Query: 188 ANSWALSSGEQWCERASPPSSSCN--------ISSGEMQKGLWEQC-QLLKSTSVFARCH 238
NSW L E C A + C+ + G ++ + C QLL+ F +CH
Sbjct: 349 GNSWRLPGSESGCLDAVEVAQGCDPLGLIDADVEPGHLRAEAQDVCHQLLEGP--FGQCH 406
Query: 239 PLVDPEPFVALCEKTLCECA-------GGLECACPALLEYARTCAQEGMVLYGWTDHSAC 291
V P + C C A G + C Y + CA+ + + W C
Sbjct: 407 AQVSPAEYHEACLFAYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIHIR-WRKPGFC 465
Query: 292 SPVCPAGMEYRQCVSPCARTCQSLHINE--MCQERCVDGCSCPEGQLLDEGLCVESTECP 349
+CP G Y CVS C +C+++ E C+E CV GC CP G + LCV + CP
Sbjct: 466 ERLCPGGQLYSDCVSLCPPSCEAVGQGEEESCREECVSGCECPRGLFWNGTLCVPAAHCP 525
Query: 350 CVHSGKRYPPGTSLSRDCNTCICRNSQWICSNEECPGECLVTGQSHFKSFDNRYFTFSGI 409
C + +RY PG ++ + CN C+CR+ +W C+ CP EC V G H+ +FD R ++F G
Sbjct: 526 CYYCRQRYVPGDTVRQLCNPCVCRDGRWHCAQALCPAECAVGGDGHYLTFDGRSYSFWGG 585
Query: 410 --CQYLLARDCQDHSFSIVIETVQCADDRDA-VCTRSVTVRLPGLHNSLVKLKHGAGVAM 466
C+Y L +D I++E C DA C +++V L H ++L+ V +
Sbjct: 586 QGCRYSLVQDYVKGQLLILLEHGAC----DAGSCLHAISVSLEDTH---IQLRDSGAVLV 638
Query: 467 DGQDVQLPLLKGDLRIQHTVTASVRLSYGEDLQMDWDGRGRL--------LVKLSPVYAG 518
+GQDV LP + + SVR + L + W G L + L P +A
Sbjct: 639 NGQDVGLPWIGAE-------GLSVRRASSAFLLLRWPGAQVLWGLSDPVAYITLDPRHAH 691
Query: 519 KTCGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWKLHGD--CQDLQKQHSDPCALNPRM 576
+ GLCG + NQ DDFLTP+G E + F + +++ G C PC + +
Sbjct: 692 QVQGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQVAGKGRCPSEDSALLSPCTTHSQR 751
Query: 577 TRFSEEACAVLTSPTFEACHRAVSPLPYLRNCRYDVCSCSDGRECLCGALASYAAACAGR 636
F+E ACA+L S F+ CHR V P+ C VC C G +CLC L++YA CA
Sbjct: 752 HAFAEAACAILHSSVFQECHRLVDKEPFYLRCLAAVCGCDPGSDCLCPVLSAYARRCAQE 811
Query: 637 GVRVAWREPGRCELNCPKGQVYLQCGTPCNLTCRSLSYPDEECNE--ACLEGCFCPPGLY 694
G WR C + CP GQ Y +C C C E+C E +C+ GC CP GL
Sbjct: 812 GASPPWRNQTLCPVMCPGGQEYRECAPACGQHCGK----PEDCGELGSCVAGCNCPLGLL 867
Query: 695 MDERGDCVPKAQCPCYYDGEIFQPEDIFSDHHTMCYCED-GFMHCTMSGVPG-SLLPDAV 752
D G CVP + CPC + P C C++ G +CT P + P +
Sbjct: 868 WDPEGQCVPPSLCPCQLGARRYAPGSATMKECNRCICQERGLWNCTARHCPSQAFCPREL 927
Query: 753 LSSPLSHRSKRSLSCRPPMVKLVCPADNLRAEGLECTKTCQNYDLECMSMGCVSGCLCPP 812
+ +P L+C P CPA G GC+CPP
Sbjct: 928 VYAP----GACLLTCDSPSANHSCPA------------------------GSTDGCVCPP 959
Query: 813 GMVRHENRCVALERCPCFHQGKEYAPGETVKIGCNTCVCRDRKWNCTDHVCDATCSTIGM 872
G V + RCV + CPC H G+ Y P T++ CN CVCR R+W+CT C G
Sbjct: 960 GTVLLDERCVPPDLCPCRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGA 1019
Query: 873 AHYLTFDGLKYLFPGECQYVLVQDYCGSNPGTFRILVGNKGCSHPSVKCKKRVTILVEGG 932
HY+TFDGL + +PG C+Y+LV++ G F + N C + C K + + +EG
Sbjct: 1020 PHYVTFDGLAFTYPGACEYLLVRE----ASGLFTVSAQNLPCGASGLTCTKALAVRLEGT 1075
Query: 933 EIELFDGE------VNVKRP-MKDETHFEVVESGRYIILLLGKALSVVWDRHLSISVVLK 985
+ + G V+V P + + +G +++L L+++WD + V L
Sbjct: 1076 VVHMLRGRAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLS 1135
Query: 986 QTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKVSSQCADTRKVPLDSSPAT 1045
++ +V GLCG+FDG +NDL S +E +SW++S C + + P
Sbjct: 1136 PQFRGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRLSPLCPEPGDL-----PHP 1190
Query: 1046 CHNNIMKQTMVDSSCRILTSDVFQDCNKLVDPEPYLDVCIYDTCSCESIGDCACFCDTIA 1105
C N + + C L +F C+ V P+ + + C+YD C C+S GDC C C IA
Sbjct: 1191 CTMNTHRAGWARARCGALLQPLFTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIA 1250
Query: 1106 AYAHVCAQHGKVVTWRTATLCPQSCEERNLRENGYECEWRYNSCAPACQVTC--QHPEP- 1162
YA CA+HG V WR+ LC CE + Y +C P C TC QHPEP
Sbjct: 1251 TYADECARHGHHVRWRSQELCSLQCEGGQV----------YEACGPTCPPTCHEQHPEPG 1300
Query: 1163 LACP-VQCVEGCHAHCPPGKILDELLQTCVDPEDCPVCEVAGRRFASGKKVTLNPSDPEH 1221
C V CVEGC CP G +L C++P CP CE F G + +
Sbjct: 1301 WHCQVVACVEGC--FCPEGTLLHG--GACLEPASCP-CEWGRNSFPPGSVL------QKD 1349
Query: 1222 CQICHC 1227
C C C
Sbjct: 1350 CGNCTC 1355
Score = 298 bits (763), Expect = 5e-80
Identities = 168/498 (33%), Positives = 231/498 (46%), Gaps = 17/498 (3%)
Query: 253 TLCECAGGLECACP--ALLEYARTCAQEGMVLYGWTD-HSACSPVCPAGMEYRQCVSPCA 309
+LC C G P A ++ C + L+ T H CP + Y C
Sbjct: 878 SLCPCQLGARRYAPGSATMKECNRCICQERGLWNCTARHCPSQAFCPRELVYAP--GACL 935
Query: 310 RTCQSLHINEMCQERCVDGCSCPEGQLLDEGLCVESTECPCVHSGKRYPPGTSLSRDCNT 369
TC S N C DGC CP G +L + CV CPC HSG+ Y P ++ DCN
Sbjct: 936 LTCDSPSANHSCPAGSTDGCVCPPGTVLLDERCVPPDLCPCRHSGQWYLPNATIQEDCNV 995
Query: 370 CICRNSQWICSNEECPGECLVTGQSHFKSFDNRYFTFSGICQYLLARDCQDHSFSIVIET 429
C+CR QW C+ + G C +G H+ +FD FT+ G C+YLL R+ F++ +
Sbjct: 996 CVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGACEYLLVREASG-LFTVSAQN 1054
Query: 430 VQCADDRDAVCTRSVTVRLPGLHNSLVKLKHGAGVAMDGQDVQLP-LLKGDLRIQHTVTA 488
+ C CT+++ VRL G ++V + G V ++G V P + G
Sbjct: 1055 LPCGAS-GLTCTKALAVRLEG---TVVHMLRGRAVTVNGVSVTPPKVYTGPGLSLRRAGL 1110
Query: 489 SVRLSYGEDLQMDWDGRGRLLVKLSPVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVED 548
+ LS L + WDG R+LV+LSP + G+ GLCG+++G+ +D + G+ EP E
Sbjct: 1111 FLLLSTHLGLTLLWDGGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVLEPTAEL 1170
Query: 549 FGNAWKLHGDCQDLQKQHSDPCALNPRMTRFSEEACAVLTSPTFEACHRAVSPLPYLRNC 608
++W+L C + PC +N ++ C L P F CH V P + C
Sbjct: 1171 AAHSWRLSPLCPE-PGDLPHPCTMNTHRAGWARARCGALLQPLFTLCHAEVPPQQHYEWC 1229
Query: 609 RYDVCSCSDGR--ECLCGALASYAAACAGRGVRVAWREPGRCELNCPKGQVYLQCGTPCN 666
YD C C G ECLC A+A+YA CA G V WR C L C GQVY CG C
Sbjct: 1230 LYDACGCDSGGDCECLCSAIATYADECARHGHHVRWRSQELCSLQCEGGQVYEACGPTCP 1289
Query: 667 LTCRSLS-YPDEECNE-ACLEGCFCPPGLYMDERGDCVPKAQCPCYYDGEIFQPEDIFSD 724
TC P C AC+EGCFCP G + G C+ A CPC + F P +
Sbjct: 1290 PTCHEQHPEPGWHCQVVACVEGCFCPEGTLL-HGGACLEPASCPCEWGRNSFPPGSVLQK 1348
Query: 725 HHTMCYCEDGFMHCTMSG 742
C C++G HC G
Sbjct: 1349 DCGNCTCQEGQWHCGGDG 1366
Score = 162 bits (411), Expect = 3e-39
Identities = 116/370 (31%), Positives = 159/370 (42%), Gaps = 26/370 (7%)
Query: 28 GRSSTARCSLFGSDFVNTFDGSMYSFAGYCSYLL---AGGCQKRSFSIIGDFQNGKRVS- 83
G+ + RC G+ TFDG +++ G C YLL A G S + +G +
Sbjct: 1007 GQRRSGRCQASGAPHYVTFDGLAFTYPGACEYLLVREASGLFTVSAQNLPCGASGLTCTK 1066
Query: 84 -LSVYLGEFFDIHLFVNGTVTQGDQRVSMP--YASKGLYLETEAGYYKLSGEAYGFVARI 140
L+V L E +H+ VT V+ P Y GL L AG + L G
Sbjct: 1067 ALAVRL-EGTVVHMLRGRAVTVNGVSVTPPKVYTGPGLSLR-RAGLFLLLSTHLGLTLLW 1124
Query: 141 DGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGEQWC 200
DG V LS ++ + GLCG+F+ A +D +++G L A+SW LS C
Sbjct: 1125 DGGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRLSP---LC 1181
Query: 201 ERASPPSSSCNISSGEMQKGLWEQCQ---LLKSTSVFARCHPLVDPEPFVALCEKTLCEC 257
C +++ + W + + LL+ +F CH V P+ C C C
Sbjct: 1182 PEPGDLPHPCTMNT---HRAGWARARCGALLQP--LFTLCHAEVPPQQHYEWCLYDACGC 1236
Query: 258 --AGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCARTCQSL 315
G EC C A+ YA CA+ G + W CS C G Y C C TC
Sbjct: 1237 DSGGDCECLCSAIATYADECARHGHHVR-WRSQELCSLQCEGGQVYEACGPTCPPTCHEQ 1295
Query: 316 HINE--MCQE-RCVDGCSCPEGQLLDEGLCVESTECPCVHSGKRYPPGTSLSRDCNTCIC 372
H CQ CV+GC CPEG LL G C+E CPC +PPG+ L +DC C C
Sbjct: 1296 HPEPGWHCQVVACVEGCFCPEGTLLHGGACLEPASCPCEWGRNSFPPGSVLQKDCGNCTC 1355
Query: 373 RNSQWICSNE 382
+ QW C +
Sbjct: 1356 QEGQWHCGGD 1365
Score = 145 bits (367), Expect = 4e-34
Identities = 124/459 (27%), Positives = 183/459 (39%), Gaps = 60/459 (13%)
Query: 1946 CPCVCTGSSTRHIVTFDGQNFKLTGS--CSYVLFQNKEQ-DLEVILHNGACSPGARQGCM 2002
CP C H +TFDG+++ G C Y L Q+ + L ++L +GAC G+ C+
Sbjct: 560 CPAECAVGGDGHYLTFDGRSYSFWGGQGCRYSLVQDYVKGQLLILLEHGACDAGS---CL 616
Query: 2003 KSIEVKHSALSVELHSDMEVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHLGHIFTFT 2062
+I V ++L V VNG+ V +P++G ++V A + G +
Sbjct: 617 HAISVSLEDTHIQLRDSGAVLVNGQDVGLPWIGAE-GLSVRRASSAFLLLRWPGAQVLWG 675
Query: 2063 PQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTVQRPGQT 2122
+ + L P+ A + GLCG +N +DF+ G V T ++ V G+
Sbjct: 676 LSDPVAYITLDPR-HAHQVQGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQVAGKGRC 734
Query: 2123 CQPILEEQCLVPDSSH----------CQVLLLPLFAECHKVLAPATFYAICQQDSCH--- 2169
P + L P ++H C +L +F ECH+++ FY C C
Sbjct: 735 --PSEDSALLSPCTTHSQRHAFAEAACAILHSSVFQECHRLVDKEPFYLRCLAAVCGCDP 792
Query: 2170 -QEQVCEVIASYAHLCRTNGVCVDWRTPDFCAMSCPPSLVYNHCEHGCPRHCDGNVSSCG 2228
+ +C V+++YA C G WR C + CP Y C C +HC G CG
Sbjct: 793 GSDCLCPVLSAYARRCAQEGASPPWRNQTLCPVMCPGGQEYRECAPACGQHC-GKPEDCG 851
Query: 2229 DHPS--EGCFCPPDKVM-LEGSCVPEEACTQCIGEDGVQHQFLEAWVPDH---QPCQICT 2282
+ S GC CP + EG CVP C +G + P + C C
Sbjct: 852 ELGSCVAGCNCPLGLLWDPEGQCVPPSLCPCQLG--------ARRYAPGSATMKECNRCI 903
Query: 2283 CLSGRKVNCTTQPCPT-AKAP-----TCGLCEVARLRQNADQCCPEYE---CVCDP---- 2329
C NCT + CP+ A P G C + +A+ CP CVC P
Sbjct: 904 CQERGLWNCTARHCPSQAFCPRELVYAPGACLLTCDSPSANHSCPAGSTDGCVCPPGTVL 963
Query: 2330 -----VSCDLPPVPHCERGLQPTLTNPGECRPNFTCACR 2363
V DL P H + P T +C C CR
Sbjct: 964 LDERCVPPDLCPCRHSGQWYLPNATIQEDCN---VCVCR 999
Score = 131 bits (330), Expect = 8e-30
Identities = 164/686 (23%), Positives = 232/686 (33%), Gaps = 134/686 (19%)
Query: 1940 CGCR---WTCPCV-----CTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKEQDLEVILHNG 1991
C CR W C C S H VTFDG F G+C Y+L + V N
Sbjct: 996 CVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGACEYLLVREASGLFTVSAQNL 1055
Query: 1992 ACSPGARQGCMKSIEVKHSALSVELHSDMEVTVNGRLVSVPYVGGNMEVNVYGAIMHEVR 2051
C C K++ V+ V + VTVNG V+ P V +++ A + +
Sbjct: 1056 PCGASGLT-CTKALAVRLEGTVVHMLRGRAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLL 1114
Query: 2052 FNHLGHIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLV 2111
HLG + +QLSP+ F + GLCG D + +ND R G + +
Sbjct: 1115 STHLG-LTLLWDGGTRVLVQLSPQ-FRGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAA 1172
Query: 2112 QEWTVQ----RPGQTCQPI-LEEQCLVPDSSHCQVLLLPLFAECHKVLAPATFYAICQQD 2166
W + PG P + + C LL PLF CH + P Y C D
Sbjct: 1173 HSWRLSPLCPEPGDLPHPCTMNTHRAGWARARCGALLQPLFTLCHAEVPPQQHYEWCLYD 1232
Query: 2167 SC------HQEQVCEVIASYAHLCRTNGVCVDWRTPDFCAMSCPPSLVYNHCEHGCPRHC 2220
+C E +C IA+YA C +G V WR+ + C++ C VY C CP C
Sbjct: 1233 ACGCDSGGDCECLCSAIATYADECARHGHHVRWRSQELCSLQCEGGQVYEACGPTCPPTC 1292
Query: 2221 DGNVSSCGDHPS-----EGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWVPDH 2275
G H EGCFCP ++ G+C+ +C G + +
Sbjct: 1293 HEQHPEPGWHCQVVACVEGCFCPEGTLLHGGACLEPASCPCEWGRNSFPPGSVL-----Q 1347
Query: 2276 QPCQICTCLSGRKVNCTTQPCPTAKAPTCGLCEVARLRQNADQCCPEYECVCDPVSCDLP 2335
+ C CTC G ++ C D C+
Sbjct: 1348 KDCGNCTCQEG-----------------------------------QWHCGGDGGHCE-E 1371
Query: 2336 PVPHCERGLQPTLTNPGECRPNFTCACRKEEC------KRVSPPSCPPHRLPTLRKTQC- 2388
VP C G + G C P+ +++C + + P C ++ T C
Sbjct: 1372 LVPACAEG-EALCQENGHCVPHGWLCDNQDDCGDGSDEEGCAAPGCGEGQM-TCSSGHCL 1429
Query: 2389 -----CD-EYECACNCVNSTVSCPLGYLASTATNDCGCTTTTCLPDKVCVHRSTIYPVGQ 2442
CD + +C + CP G LA C CLP +
Sbjct: 1430 PLALLCDRQDDCGDGTDEPSYPCPQGLLA--------CADGRCLPPALL----------- 1470
Query: 2443 FWEEGCD-VCTCTDMEDAVMGLRVAQCSQKPCEDSCRSGFTYVLHEGECC-GRCLPS--A 2498
CD C D D E+SC T V E C G CL +
Sbjct: 1471 -----CDGHPDCLDAAD---------------EESCLGQVTCVPGEVSCVDGTCLGAIQL 1510
Query: 2499 CEVVTGSPRGDSQSSWKSVGSQWASPENPCLINECVRVKEEVFIQQRNVSCPQLEVPVCP 2558
C+ V P G + +P L + + S P P
Sbjct: 1511 CDGVWDCPDGADEGPGHCPLPSLPTPPASTLPGPSPGSLDTASSPLASAS------PAPP 1564
Query: 2559 SG-FQLSCKTSACCP-SCRCERMEAC 2582
G F+ C + C P RC++ E C
Sbjct: 1565 CGPFEFRCGSGECTPRGWRCDQEEDC 1590
Score = 94.0 bits (232), Expect = 2e-18
Identities = 98/396 (24%), Positives = 148/396 (37%), Gaps = 77/396 (19%)
Query: 1950 CTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKEQDLEVILHNGACSPGARQGCMKSIEVKH 2009
C S H TFDG+++ G C+Y+L + V L G P + G + + +
Sbjct: 195 CASWSGFHYRTFDGRHYHFLGRCTYLLAGAADSTWAVHLTPGDRCP--QPGHCQRVTMGP 252
Query: 2010 SALSVELHSDMEVTVNGRLV-----------SVPYVGGNMEVNVYGAIMHEVRFNHLGHI 2058
+ ++ + V+V G+LV S+ ++G + ++ G + VR + G I
Sbjct: 253 EEVLIQAGN---VSVKGQLVPEGQSWLLHGLSLQWLGDWLVLS--GGLGVVVRLDRTGSI 307
Query: 2059 FTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTVQR 2118
+T GLCG+ + +DFM G + T W +
Sbjct: 308 SISVDHE-----------LWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRL-- 354
Query: 2119 PG------------QTCQPI------LEEQCLVPDSSH-CQVLLLPLFAECHKVLAPATF 2159
PG Q C P+ +E L ++ C LL F +CH ++PA +
Sbjct: 355 PGSESGCLDAVEVAQGCDPLGLIDADVEPGHLRAEAQDVCHQLLEGPFGQCHAQVSPAEY 414
Query: 2160 YAICQQDSC-----------HQEQVCEVIASYAHLCRTNGVCVDWRTPDFCAMSCPPSLV 2208
+ C C Q+ VC ASY C + + WR P FC CP +
Sbjct: 415 HEACLFAYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIHIRWRKPGFCERLCPGGQL 474
Query: 2209 YNHCEHGCPRHCD----GNVSSCGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQ 2264
Y+ C CP C+ G SC + GC CP CVP C C
Sbjct: 475 YSDCVSLCPPSCEAVGQGEEESCREECVSGCECPRGLFWNGTLCVPAAHC-PC------- 526
Query: 2265 HQFLEAWVPD---HQPCQICTCLSGRKVNCTTQPCP 2297
+ + +VP Q C C C GR +C CP
Sbjct: 527 YYCRQRYVPGDTVRQLCNPCVCRDGR-WHCAQALCP 561
Score = 90.5 bits (223), Expect = 2e-17
Identities = 65/239 (27%), Positives = 89/239 (37%), Gaps = 53/239 (22%)
Query: 652 CPKGQVYLQCGTPCNLTCRSLSYPDEEC-NEACLEGCFCPPGLYMDERGDCVPKAQCPCY 710
CP GQV C T C C L P C E C GC CP G + G CVP CPC
Sbjct: 4818 CPPGQVLSACATSCPCLCWHLQ-PGAICVQEPCQPGCGCPGGQLL-HNGTCVPPTACPCT 4875
Query: 711 Y-------------DGEIFQPEDIFSDHHTMCYCEDGFMHCTMSGVPGSLLPDAVLSSPL 757
+ P + + + T C C G C++
Sbjct: 4876 QHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSL----------------- 4918
Query: 758 SHRSKRSLSCRPPMVKL---VCPADNLRAEGLECTKTCQNYDLECMSMGC----VSGCLC 810
+ C+ P + V P + GL C +TC + C SGC+C
Sbjct: 4919 -------VDCQVPPGETWQQVAPGEL----GL-CEQTCLEMNATKTQSNCSSARASGCVC 4966
Query: 811 PPGMVRHE-NRCVALERCPCFHQGKEYAPGETVKIGCNTCVCRDRKWNCTDHVCDATCS 868
PG R + CV + C C+H G+ + PG + C +C+C + CT H TC+
Sbjct: 4967 QPGHFRSQAGPCVPEDHCECWHLGRPHLPGSEWQEACESCLCLSGRPVCTQHCSPLTCA 5025
Score = 83.6 bits (205), Expect = 3e-15
Identities = 44/112 (39%), Positives = 52/112 (46%), Gaps = 17/112 (15%)
Query: 293 PVCPAGMEYRQCVSPCARTCQSLHINEMC-QERCVDGCSCPEGQLLDEGLCVESTECPCV 351
P CP G C + C C L +C QE C GC CP GQLL G CV T CPC
Sbjct: 4816 PECPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPGCGCPGGQLLHNGTCVPPTACPCT 4875
Query: 352 -HS------------GKRYPPGTSLSRDCNTCICRNSQWICSNEEC---PGE 387
HS + PPGT L+R+C C+C + CS +C PGE
Sbjct: 4876 QHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDCQVPPGE 4927
Score = 80.9 bits (198), Expect = 2e-14
Identities = 164/743 (22%), Positives = 242/743 (32%), Gaps = 164/743 (22%)
Query: 2202 SCPPSLVYNHCEHGCPRHCDGNVSS--CGDHP--SEGCFCPPDKVMLEGSCVPEEACTQC 2257
SC P ++ C C C ++S C D P GC+CP + G C+P E C
Sbjct: 4422 SCTPPFEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCPKGLLEQAGGCIPPEECNCW 4481
Query: 2258 IGEDGVQHQFLEAWVPDHQPCQICTCLSGRKVNCTTQPCPT-------AKAPTCGLCEVA 2310
L C+ C C G +++CT+Q C ++ CG C
Sbjct: 4482 HTSAAGAGMTLAPGDRLQLGCKECECRRG-ELHCTSQGCQGLLPLSEWSEWSPCGPCLPP 4540
Query: 2311 RLRQNADQCCPEYECVCDP--VSCDLPPVPHCERG-----LQPTLTNPGECRPNFTCACR 2363
A + E + DP +S L P+ E+ L P P P+ A
Sbjct: 4541 SALAPASRTALEEHWLRDPTGLSPTLAPLLASEQHRHRLCLDPATGRPWTGAPHLCTAPL 4600
Query: 2364 KEECKRVSPPSCPPHRLPTLRKTQCCDEYECA----CNCVNSTVSCPLGYLASTATNDCG 2419
++ P +CP +L + C+ + C G A C
Sbjct: 4601 SQQRLCPDPGACPDSCQWSLWGPWSPCQVPCSGGFRLRWREAEALCGGGCREPWAQESCN 4660
Query: 2420 CTTTTCLPDKVCVHRSTIYPVGQFWEEGCDVC--TCTDMEDAVMGLRVAQCSQKPCEDSC 2477
P C + T++ + + + C +C D+ D V QC Q PC C
Sbjct: 4661 GG-----PCPECEAQDTVFTL-----DCANQCPHSCADLWDRV------QCLQGPCRPGC 4704
Query: 2478 RSGFTYVLHEGEC-----CGRCLPSA------------------CEVVTGS--------P 2506
R ++ +G C C LPSA C V S P
Sbjct: 4705 RCPPGQLVQDGRCVPISSCRCGLPSANASWELAPAQAVQLDCQNCTCVNESLVCPHQECP 4764
Query: 2507 RGDSQSSWKSV----GSQWASPENPCLINECVRVKEEVFIQQRNVSCPQLEVPVCPSGFQ 2562
S+W S G C V + +QR C P CP G
Sbjct: 4765 VLGPWSAWSSCSAPCGGGTMERHRTCEGGPGVAPCQAQDTEQRQ-ECNLQPCPECPPGQV 4823
Query: 2563 LS-CKTSACC-----------------PSCRCERMEACMLNGTVIGPGK----------- 2593
LS C TS C P C C + + NGT + P
Sbjct: 4824 LSACATSCPCLCWHLQPGAICVQEPCQPGCGCPGGQL-LHNGTCVPPTACPCTQHSLPWG 4882
Query: 2594 ---------------TVMIDVCTTCRCMVQVGVISGFKLECRKTTCN------PCPLGYK 2632
TV+ CT C C G S ++C+ P LG
Sbjct: 4883 LTLTLEEQAQELPPGTVLTRNCTRCVC--HGGAFSCSLVDCQVPPGETWQQVAPGELGLC 4940
Query: 2633 EEN-------NTGECCGRCLPTACTIQLRGGQIMTLKRDETLQDGCDT-HFCKVNERGEY 2684
E+ T C + C Q G + +D C+ H + + G
Sbjct: 4941 EQTCLEMNATKTQSNCSSARASGCVCQ--PGHFRSQAGPCVPEDHCECWHLGRPHLPGSE 4998
Query: 2685 FWEKRVTGC------PPFDEH---KCLAEGGKIMKIPGTCCDTC-------EEPECNDIT 2728
W++ C P +H A+G +++ PG+CC +C + P C +T
Sbjct: 4999 -WQEACESCLCLSGRPVCTQHCSPLTCAQGEEMVLEPGSCCPSCRREAPEEQSPSCQLLT 5057
Query: 2729 ARLQYVKVGSCKSEVEVDIHYCQGKCASKAMYSIDINDVQDQCSCCSPTRTEPMQ----V 2784
+ K G+C + +V++ YC G C S + +Q QC CCS R +P +
Sbjct: 5058 ELRNFTK-GTCYLD-QVEVSYCSGYCPSSTHVMPEEPYLQSQCDCCS-YRLDPESPVRIL 5114
Query: 2785 ALHCTNGSVVYHEVLNAMECKCS 2807
L C G + C+CS
Sbjct: 5115 NLRCLGGHTEPVVLPVIHSCQCS 5137
Score = 79.3 bits (194), Expect = 5e-14
Identities = 37/98 (37%), Positives = 48/98 (48%), Gaps = 3/98 (3%)
Query: 291 CSPVCPAGMEYRQCVSPCARTCQSLHINEMCQER--CVDGCSCPEGQLLDEGLCVESTEC 348
C CPAGME C + C R C L +CQ+ C GC CP+G L +G CV C
Sbjct: 4058 CEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVPIGHC 4117
Query: 349 PCVHS-GKRYPPGTSLSRDCNTCICRNSQWICSNEECP 385
C + G + PG+ CN C C+ Q C+ + CP
Sbjct: 4118 DCTDAQGHSWAPGSQHQDACNNCSCQAGQLSCTAQPCP 4155
Score = 78.6 bits (192), Expect = 8e-14
Identities = 73/284 (25%), Positives = 97/284 (34%), Gaps = 75/284 (26%)
Query: 651 NCPKGQVYLQCGTPCNLTCRSLSYPDEECNEA---CLEGCFCPPGLYMDERGDCVPKAQC 707
+C GQ CG PC +C+ LS P C C C CP G + + G CVP A C
Sbjct: 3528 DCGGGQSLHPCGQPCPRSCQDLS-PGSVCQPGSVGCQPTCGCPLG-QLSQDGLCVPPAHC 3585
Query: 708 PCYYDG--------------------EIFQPEDIFSDHHTMCYCEDGFMHCTM------S 741
C Y E +P ++ + C C G + C
Sbjct: 3586 RCQYQPGAMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEVPDCPDP 3645
Query: 742 GVPGSLLP--DAVLSSPLSHRSKRSLSCRPPMV---------------KLVCPADNLRAE 784
GV S P D +S + + RPP + CPA L E
Sbjct: 3646 GVWSSWGPWEDCSVSCGGGEQLRSRRCARPPCPGPARQSRTCSTQVCREAGCPAGRLYRE 3705
Query: 785 ---GLECTKTCQNYDLE--CMSMGCVSGCLCPPGMVRHENRCVALERCPC---------- 829
G C +C + + C S GC GC CP G +H CV + CPC
Sbjct: 3706 CQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRLACV--QECPCVLTAWLLQEL 3763
Query: 830 ----------FHQGKEYAPGETVKIGCNTCVCRDRKWNCTDHVC 863
G E G+T++ C C C K +C+ C
Sbjct: 3764 GATIGDPGQPLGPGDELDSGQTLRTSCGNCSCAHGKLSCSLDDC 3807
Score = 76.3 bits (186), Expect = 4e-13
Identities = 63/240 (26%), Positives = 83/240 (34%), Gaps = 61/240 (25%)
Query: 186 DFANSWALSSGEQWCERASPPSSSCNISSGEMQKGLWEQCQLLKSTSVFARCHPLVDPEP 245
D N+ SG+ C S C ++ G LW C + + R P
Sbjct: 2963 DSCNNCTCVSGKMACT-----SERCPVACGWSPWTLWSLCSCSCNVGIRRRFRAGTAPPA 3017
Query: 246 FVALCEKTLCECAGGLECACPAL-LEYA--RTCAQEGMVLYGWTDHSACSPVCPAG---- 298
GG EC P + E+ R C G W S CS C G
Sbjct: 3018 -----------AFGGAECQGPTMEAEFCSLRPCPGPGGE---WGPWSPCSVPCGGGYRNR 3063
Query: 299 --------MEYRQC-VSPCA--------------------RTCQSLHINEMCQERCVDGC 329
ME+ C + PCA +C L + C GC
Sbjct: 3064 TRGSSRSLMEFSTCGLQPCAGPVPGMCPRDKQWLDCAQGPASCAELSAPRGTNQTCHPGC 3123
Query: 330 SCPEGQLLDEGLCVESTECPCVHSGKRYPPGTSLSRDCNTCICRN------SQWICSNEE 383
CP G LL +CV + +CPC H G YPPG+++ R C C C + S W C+ E
Sbjct: 3124 HCPSGMLLLNNVCVPTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANCSSWPCAEGE 3183
Score = 75.1 bits (183), Expect = 9e-13
Identities = 49/166 (29%), Positives = 67/166 (40%), Gaps = 15/166 (9%)
Query: 237 CHPLVDPEPFV----ALCEKTLCECAGGLEC---ACPALLEYARTCAQEGMVLYGWTDHS 289
C P V P P + A C GG++ +C +L TC +
Sbjct: 2822 CSPPVCPVPSIWGLWAPWSTCSAPCDGGIQTRGRSCSSLAPGDTTCPGPHSQTRD-CNTQ 2880
Query: 290 ACSPVCPAGMEYR---QCVS---PCARTCQSLHINEMCQERCVDGCSCPEGQLLDEGLCV 343
C+ CP M +R QC PC R C + C C GC+CP G L C+
Sbjct: 2881 PCTAQCPENMLFRSAEQCHQEGGPCPRLCLTQGPGIECTGFCAPGCTCPPGLFLHNASCL 2940
Query: 344 ESTECPCVHSGKRYPPGTSLSRD-CNTCICRNSQWICSNEECPGEC 388
++CPC G+ Y G D CN C C + + C++E CP C
Sbjct: 2941 PRSQCPCQLHGQLYASGAMARLDSCNNCTCVSGKMACTSERCPVAC 2986
Score = 73.6 bits (179), Expect = 3e-12
Identities = 90/352 (25%), Positives = 124/352 (35%), Gaps = 80/352 (22%)
Query: 2199 CAMSCPPSLVYN-----HCEHG-CPRHC--DGNVSSCGDHPSEGCFCPPDKVMLEGSCVP 2250
C CP ++++ H E G CPR C G C + GC CPP + SC+P
Sbjct: 2882 CTAQCPENMLFRSAEQCHQEGGPCPRLCLTQGPGIECTGFCAPGCTCPPGLFLHNASCLP 2941
Query: 2251 EEAC-TQCIGEDGVQHQFLEAWVPDHQPCQICTCLSGRKVNCTTQPCPTAKAPTCG---- 2305
C Q G+ + + C CTC+SG K+ CT++ CP A CG
Sbjct: 2942 RSQCPCQLHGQ-----LYASGAMARLDSCNNCTCVSG-KMACTSERCPVA----CGWSPW 2991
Query: 2306 ----LCEVA-----RLRQNADQCCPE----YEC---VCDPVSCDLPPVP----------- 2338
LC + R R A P EC + C L P P
Sbjct: 2992 TLWSLCSCSCNVGIRRRFRAGTAPPAAFGGAECQGPTMEAEFCSLRPCPGPGGEWGPWSP 3051
Query: 2339 ---HCERGLQPTLTNPGECRPNFTCACRKEECKRVSPPSCPPHRLPTLRKTQCCDEYECA 2395
C G + F+ C + C P CP R Q D +
Sbjct: 3052 CSVPCGGGYRNRTRGSSRSLMEFS-TCGLQPCAGPVPGMCP-------RDKQWLDCAQGP 3103
Query: 2396 CNCVNSTVSCPLGYLASTATNDCGCTT------TTCLP--DKVCVHRSTIYPVGQFWEEG 2447
+C + +S P G T C C + C+P D C H +YP G
Sbjct: 3104 ASC--AELSAPRG-TNQTCHPGCHCPSGMLLLNNVCVPTQDCPCAHEGHLYPPGSTVVRP 3160
Query: 2448 CDVCTCTDMEDAVMGLRVAQCSQKPCEDSCRSGFTYVLHEGECCGRCLPSAC 2499
C+ C+C V GL +A CS PC + ++ +C C P+ C
Sbjct: 3161 CENCSC------VSGL-IANCSSWPCAEG-EPTWSPWTPWSQCSASCGPARC 3204
Score = 72.8 bits (177), Expect = 5e-12
Identities = 53/191 (27%), Positives = 76/191 (39%), Gaps = 36/191 (18%)
Query: 209 SCNISSGEMQKGLWEQCQLLKSTSVFARCHPLVDPEPFV-------ALCEKTLC---ECA 258
+C ++ W C + +R VDP P A E+ C C+
Sbjct: 2551 ACPVAGAWAMWEAWGPCSVSCGGGHQSRQRSCVDPPPKNGGAPCPGASQERAPCGLQPCS 2610
Query: 259 GGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCARTCQSLHIN 318
GG +C + A C Q+G+V P CP C+ P A N
Sbjct: 2611 GGTDCELGRVYVSADLC-QKGLV-----------PPCPPS-----CLDPKA--------N 2645
Query: 319 EMCQERCVDGCSCPEGQLLDEGLCVESTECPCVHSGKRYPPGTS-LSRDCNTCICRNSQW 377
C CV+GC CP G LL + C+ +ECPC+ + PG S L +C+ C+C +
Sbjct: 2646 RSCSGHCVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFLLGNCSQCVCEKGEL 2705
Query: 378 ICSNEECPGEC 388
+C CP C
Sbjct: 2706 LCQPGGCPLPC 2716
Score = 71.6 bits (174), Expect = 1e-11
Identities = 50/166 (30%), Positives = 68/166 (40%), Gaps = 16/166 (9%)
Query: 593 EACHRAVSPLPYLRN--CRYDVCS--CSDG---RECLCGALASYAAACAGRGVRVAWREP 645
E C V P+P + + CS C G R C +LA C G +
Sbjct: 2820 EPCSPPVCPVPSIWGLWAPWSTCSAPCDGGIQTRGRSCSSLAPGDTTCPGPHSQTRDCNT 2879
Query: 646 GRCELNCPKGQVYL---QC---GTPCNLTCRSLSYPDEECNEACLEGCFCPPGLYMDERG 699
C CP+ ++ QC G PC C + P EC C GC CPPGL++
Sbjct: 2880 QPCTAQCPENMLFRSAEQCHQEGGPCPRLCLTQG-PGIECTGFCAPGCTCPPGLFL-HNA 2937
Query: 700 DCVPKAQCPCYYDGEIFQPEDIFS-DHHTMCYCEDGFMHCTMSGVP 744
C+P++QCPC G+++ + D C C G M CT P
Sbjct: 2938 SCLPRSQCPCQLHGQLYASGAMARLDSCNNCTCVSGKMACTSERCP 2983
Score = 71.2 bits (173), Expect = 1e-11
Identities = 39/120 (32%), Positives = 50/120 (41%), Gaps = 9/120 (7%)
Query: 756 PLSHRSKRSLSCRP-----PMVKLVCPADNLRAEGLECTKTC--QNYDLECMSMGCVSGC 808
P H R + +P P L A+ EG C + C Q +EC C GC
Sbjct: 2868 PGPHSQTRDCNTQPCTAQCPENMLFRSAEQCHQEGGPCPRLCLTQGPGIECTGF-CAPGC 2926
Query: 809 LCPPGMVRHENRCVALERCPCFHQGKEYAPGETVKI-GCNTCVCRDRKWNCTDHVCDATC 867
CPPG+ H C+ +CPC G+ YA G ++ CN C C K CT C C
Sbjct: 2927 TCPPGLFLHNASCLPRSQCPCQLHGQLYASGAMARLDSCNNCTCVSGKMACTSERCPVAC 2986
Score = 70.9 bits (172), Expect = 2e-11
Identities = 34/99 (34%), Positives = 47/99 (47%), Gaps = 7/99 (7%)
Query: 295 CPAGMEYRQCVSPCARTCQSLHINEMCQER--CVDGCSCPEGQLLDEGLCVESTECPCVH 352
C E+ C SPCA C + +++CQ+ C GC CP+G L G C+ EC C H
Sbjct: 4423 CTPPFEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCPKGLLEQAGGCIPPEECNCWH 4482
Query: 353 -----SGKRYPPGTSLSRDCNTCICRNSQWICSNEECPG 386
+G PG L C C CR + C+++ C G
Sbjct: 4483 TSAAGAGMTLAPGDRLQLGCKECECRRGELHCTSQGCQG 4521
Score = 69.3 bits (168), Expect = 5e-11
Identities = 36/94 (38%), Positives = 48/94 (51%), Gaps = 9/94 (9%)
Query: 298 GMEYRQCVSPCARTCQSLHINEMCQERCVDGCSCPEGQLLDE--GLCVESTECPCVH--S 353
G EY C PC R+C L C RC GC CP GQ+L +CV+ C C+ +
Sbjct: 3316 GAEYSPCGPPCPRSCDDL---VHCVWRCQPGCYCPPGQVLSSNGAICVQPGHCSCLDLLT 3372
Query: 354 GKRYPPGTSLSR--DCNTCICRNSQWICSNEECP 385
G+R+ PG L+R CN C C + C++ CP
Sbjct: 3373 GQRHHPGARLARPDGCNHCTCLEGRLNCTDLPCP 3406
Score = 68.6 bits (166), Expect = 9e-11
Identities = 157/746 (21%), Positives = 225/746 (30%), Gaps = 197/746 (26%)
Query: 250 CEKTLCECAGGL----ECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQ-- 303
C++ C G + ECA P E L W+ S C C G + R
Sbjct: 4233 CQRCSCTPEGVICEDTECAVP-----------EAWTL--WSSWSDCPVSCGGGNQVRTRA 4279
Query: 304 ------------CVSPCARTCQSLHINEMCQ---ERCVDGCSCPEGQLLDEGLCVESTEC 348
C+ P +T Q + C E C G P + GL S C
Sbjct: 4280 CRAAAPHHRSPPCLGPDTQTRQ-----QPCPGLLEACSWGPWGPCSRSCGPGLASRSGSC 4334
Query: 349 PCVHSGKRYPPGTSLSRDCNTCICRNSQWICSNEECPGECLVTGQSHFKSFDNRYFT--- 405
PC+ + CN+ C + CP EC+ + S + R
Sbjct: 4335 PCLMA--------KADPTCNSTFLHLDTQGCYSGPCPEECVWSSWSSWTRCSCRVLVQQR 4386
Query: 406 -------------------FSGICQYLLARDCQDHSFSIVIETVQCADDRDAVCTRSVTV 446
G + L +C + S + E C +C ++
Sbjct: 4387 YRHQGPASRGARAGAPCTRLDGHFRPCLISNCSEDSCTPPFEFHACGSPCAGLCATHLSH 4446
Query: 447 RL--------PGLHNSLVKLKHGAGVAMDGQDVQLPLLKGDLRIQHTVTASVRLSYGEDL 498
+L PG + L+ G +P + + A + L+ G+ L
Sbjct: 4447 QLCQDLPPCQPGCYCPKGLLEQAGGC--------IPPEECNCWHTSAAGAGMTLAPGDRL 4498
Query: 499 QMDWDG----RGRL---------LVKLSPVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPR 545
Q+ RG L L+ LS CG C L PS LA
Sbjct: 4499 QLGCKECECRRGELHCTSQGCQGLLPLSEWSEWSPCGPC-----------LPPSALAPAS 4547
Query: 546 VEDFGNAWKLHGDCQDLQKQHSDPCALNPRMT------RFSEEACA--VLTSPTFEACHR 597
W DP L+P + + C P A H
Sbjct: 4548 RTALEEHWL------------RDPTGLSPTLAPLLASEQHRHRLCLDPATGRPWTGAPHL 4595
Query: 598 AVSPLPYLRNCRYDVCSCSDGRE-CLCGALASYAAACAGRGVRVAWREP-----GRCELN 651
+PL R C D +C D + L G + C+G G R+ WRE G C
Sbjct: 4596 CTAPLSQQRLCP-DPGACPDSCQWSLWGPWSPCQVPCSG-GFRLRWREAEALCGGGCREP 4653
Query: 652 ----------CPKGQVY-----LQCGTPCNLTCRSLSYPDEECNEACLEGCFCPPGLYMD 696
CP+ + L C C +C L + C GC CPPG +
Sbjct: 4654 WAQESCNGGPCPECEAQDTVFTLDCANQCPHSCADLWDRVQCLQGPCRPGCRCPPGQLVQ 4713
Query: 697 ERGDCVPKAQCPCYYDG-----EIFQPEDIFSDHHTMCYCEDGFMHCTMSGVP--GSLLP 749
+ G CVP + C C E+ + + D C C + + C P G
Sbjct: 4714 D-GRCVPISSCRCGLPSANASWELAPAQAVQLDCQN-CTCVNESLVCPHQECPVLGPWSA 4771
Query: 750 DAVLSSPLS------HRS---------------KRSLSCRPPMVKLVCPADNLRAEGLEC 788
+ S+P HR+ ++ C P L A C
Sbjct: 4772 WSSCSAPCGGGTMERHRTCEGGPGVAPCQAQDTEQRQECNLQPCPECPPGQVLSACATSC 4831
Query: 789 TKTCQNYD--LECMSMGCVSGCLCPPGMVRHENRCVALERCPCF-------------HQG 833
C + C+ C GC CP G + H CV CPC Q
Sbjct: 4832 PCLCWHLQPGAICVQEPCQPGCGCPGGQLLHNGTCVPPTACPCTQHSLPWGLTLTLEEQA 4891
Query: 834 KEYAPGETVKIGCNTCVCRDRKWNCT 859
+E PG + C CVC ++C+
Sbjct: 4892 QELPPGTVLTRNCTRCVCHGGAFSCS 4917
Score = 67.4 bits (163), Expect = 2e-10
Identities = 128/548 (23%), Positives = 177/548 (32%), Gaps = 166/548 (30%)
Query: 2199 CAMSCPPSLVYNHCEHGCPRHC----DGNVSSCGDHPSEGCFCPPDKVMLEGSCVPEEAC 2254
C CP + C + CPR C +G V +GC CP + +G CVP C
Sbjct: 4058 CEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVPIGHC 4117
Query: 2255 TQCIGEDGVQHQFLEAWVPDHQ---PCQICTCLSGRKVNCTTQPCPTAKAPTCGLCEVAR 2311
C G +W P Q C C+C +G +++CT QPCP PT
Sbjct: 4118 -DCTDAQG------HSWAPGSQHQDACNNCSCQAG-QLSCTAQPCP---PPT-------- 4158
Query: 2312 LRQNADQCCPEYECVCDPVSCDLPPVPHCERGLQPTL--TNPGECRPNFTCACRKEECKR 2369
C + P S P RG Q + G P CR+E+ +
Sbjct: 4159 ------HCAWSHWSAWSPCSHSCGP-----RGQQSRFRSSTSGSWAPE----CREEQSQS 4203
Query: 2370 --VSPPSCPPHRLPTLRKTQCCDEY---EC-ACNCVNSTVSC-------PLGYLASTATN 2416
PSCPP L R D + EC C+C V C P + ++ +
Sbjct: 4204 QPCPQPSCPPLCLQGTRSRTLGDSWLQGECQRCSCTPEGVICEDTECAVPEAWTLWSSWS 4263
Query: 2417 DC--GCTTTTCLPDKVC-----VHRS--TIYPVGQFWEEGC----DVCT------CTDME 2457
DC C + + C HRS + P Q ++ C + C+ C+
Sbjct: 4264 DCPVSCGGGNQVRTRACRAAAPHHRSPPCLGPDTQTRQQPCPGLLEACSWGPWGPCSRSC 4323
Query: 2458 DAVMGLRVAQCSQKPC-----EDSCRSGFTYVLHEGECCGRCLPSACEVVTGSPRGDSQS 2512
+ R C PC + +C S F ++ +G G C P C S S
Sbjct: 4324 GPGLASRSGSC---PCLMAKADPTCNSTFLHLDTQGCYSGPC-PEECV-------WSSWS 4372
Query: 2513 SW------------------KSVGSQWASP-------ENPCLINECVRVKEEVFIQQRNV 2547
SW S G++ +P PCLI+ C +
Sbjct: 4373 SWTRCSCRVLVQQRYRHQGPASRGARAGAPCTRLDGHFRPCLISNC----------SEDS 4422
Query: 2548 SCPQLEVPVCPS----------GFQLSCKTSACCPSCRC-----ERMEACML-------- 2584
P E C S QL C P C C E+ C+
Sbjct: 4423 CTPPFEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCPKGLLEQAGGCIPPEECNCWH 4482
Query: 2585 -----NGTVIGPGKTVMIDVCTTCRCMVQVGVISGFKLECRKTTCNP-CPLGYKEENNTG 2638
G + PG + + C C C +L C C PL E +
Sbjct: 4483 TSAAGAGMTLAPGDRLQLG-CKECEC-------RRGELHCTSQGCQGLLPL---SEWSEW 4531
Query: 2639 ECCGRCLP 2646
CG CLP
Sbjct: 4532 SPCGPCLP 4539
Score = 66.6 bits (161), Expect = 3e-10
Identities = 41/128 (32%), Positives = 57/128 (44%), Gaps = 13/128 (10%)
Query: 273 RTCAQEGMVLYGWTDHSAC------SPVCPAGMEYRQCVSPCARTCQSLHINEMCQERCV 326
RTCA L+ C + C + ++ C +PC TC + C
Sbjct: 1784 RTCAALPGGLHSTRQTKPCPQDGCPNATCSGELMFQPC-APCPLTCDDISGQVTCPPDWP 1842
Query: 327 ---DGCSCPEGQLL-DEGLCVESTECPCVHSGKRYPPGTSLSRDCNTCICRNS--QWICS 380
GC CPEGQ+L EG CV +CPC+ G RY PG + DC CIC++ +
Sbjct: 1843 CGSPGCWCPEGQVLGSEGWCVWPRQCPCLVDGARYWPGQRIKADCQLCICQDGRPRRCRL 1902
Query: 381 NEECPGEC 388
N +C +C
Sbjct: 1903 NPDCAVDC 1910
Score = 63.5 bits (153), Expect = 3e-09
Identities = 30/99 (30%), Positives = 40/99 (40%), Gaps = 12/99 (12%)
Query: 764 SLSCRPPMVKLVCPADNLRAEGLECTKTCQNYDLE----CMSMGCVSGCLCPPGMVRHEN 819
SL C V C G C TC E C + CV GC CP G + H
Sbjct: 1272 SLQCEGGQVYEAC--------GPTCPPTCHEQHPEPGWHCQVVACVEGCFCPEGTLLHGG 1323
Query: 820 RCVALERCPCFHQGKEYAPGETVKIGCNTCVCRDRKWNC 858
C+ CPC + PG ++ C C C++ +W+C
Sbjct: 1324 ACLEPASCPCEWGRNSFPPGSVLQKDCGNCTCQEGQWHC 1362
Score = 62.8 bits (151), Expect = 5e-09
Identities = 53/186 (28%), Positives = 70/186 (37%), Gaps = 15/186 (8%)
Query: 595 CHRAVSPLP--YLRNCRYDVC--SCSDG-----RECLCGALASYAAACAGRGVRVAWREP 645
C+ P+P + R + C SC G R C + A CAG + P
Sbjct: 3996 CNLRACPVPGGWSRWSPWSWCDRSCGGGQSLRSRSCSSPPSKNGGAPCAGERHQARLCNP 4055
Query: 646 GRCELNCPKGQVYLQCGTPCNLTCRSLSYPDE-ECNEACLEGCFCPPGLYMDERGDCVPK 704
CE CP G + C C C L + ++ C +GC CP G +++ G CVP
Sbjct: 4056 MPCEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKG-SLEQDGGCVPI 4114
Query: 705 AQCPCY-YDGEIFQPEDIFSDHHTMCYCEDGFMHCTMSGVPGSLLPDAVLSSPLSHRSKR 763
C C G + P D C C+ G + CT P P S S S
Sbjct: 4115 GHCDCTDAQGHSWAPGSQHQDACNNCSCQAGQLSCTAQPCPP---PTHCAWSHWSAWSPC 4171
Query: 764 SLSCRP 769
S SC P
Sbjct: 4172 SHSCGP 4177
Score = 62.4 bits (150), Expect = 6e-09
Identities = 82/358 (22%), Positives = 117/358 (32%), Gaps = 83/358 (23%)
Query: 538 PSGLAEPRVEDFGNAWKLHGDCQDLQKQHSDPCALNPRMTRFSEEACAVLTSPTFEACHR 597
P L R G++W L G+CQ C+ P + CAV P
Sbjct: 4213 PLCLQGTRSRTLGDSW-LQGECQR--------CSCTPEGVICEDTECAV---PEAWTLWS 4260
Query: 598 AVSPLPYL----RNCRYDVCSCSDGRE----CLCGALASYAAACAGRGVRVAWREPGRCE 649
+ S P R C + CL + C G +W G C
Sbjct: 4261 SWSDCPVSCGGGNQVRTRACRAAAPHHRSPPCLGPDTQTRQQPCPGLLEACSWGPWGPCS 4320
Query: 650 LNCPKGQVYLQCGTPCNLTCRSLSYPDEECNEACL----EGCFCPPGLYMDERGDCVPKA 705
+C G PC ++ D CN L +GC+ P
Sbjct: 4321 RSCGPGLASRSGSCPC-----LMAKADPTCNSTFLHLDTQGCYSGP-------------- 4361
Query: 706 QCPCYYDGEIFQPEDIFSDHH--TMCYC----EDGFMHC------TMSGVPGSLLPDAVL 753
CP E ++S T C C + + H +G P + L
Sbjct: 4362 -CP---------EECVWSSWSSWTRCSCRVLVQQRYRHQGPASRGARAGAPCTRLDGHFR 4411
Query: 754 SSPLSHRSKRSLSCRPPMVKLVCPADNLRAEGLECTKTCQNYDLE--CMSMG-CVSGCLC 810
+S+ S+ S C PP C G C C + C + C GC C
Sbjct: 4412 PCLISNCSEDS--CTPPFEFHAC--------GSPCAGLCATHLSHQLCQDLPPCQPGCYC 4461
Query: 811 PPGMVRHENRCVALERCPCFH-----QGKEYAPGETVKIGCNTCVCRDRKWNCTDHVC 863
P G++ C+ E C C+H G APG+ +++GC C CR + +CT C
Sbjct: 4462 PKGLLEQAGGCIPPEECNCWHTSAAGAGMTLAPGDRLQLGCKECECRRGELHCTSQGC 4519
Score = 61.2 bits (147), Expect = 1e-08
Identities = 42/160 (26%), Positives = 57/160 (35%), Gaps = 24/160 (15%)
Query: 250 CEKTLCECAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCA 309
C+ L + C+ P E R C ++S C G C PC
Sbjct: 3484 CDMCLGQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQENSTQCTDCGGGQSLHPCGQPCP 3543
Query: 310 RTCQSLHINEMCQER---CVDGCSCPEGQLLDEGLCVESTECPCVH-------------- 352
R+CQ L +CQ C C CP GQL +GLCV C C +
Sbjct: 3544 RSCQDLSPGSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAHCRCQYQPGAMGIPENQSRS 3603
Query: 353 SGKRY------PPGTSLSRDCNTCICRNSQWICSN-EECP 385
+G R+ PG ++ C+ C C C +CP
Sbjct: 3604 AGSRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEVPDCP 3643
Score = 60.8 bits (146), Expect = 2e-08
Identities = 57/214 (26%), Positives = 80/214 (37%), Gaps = 51/214 (23%)
Query: 207 SSSCNISSGEMQKGLWEQCQLLKSTSVFARCHPLVD-PEPFV----ALCEKTLCECAGGL 261
SS ++ GE+ G + C + +C + D P+P V E C GG
Sbjct: 3609 SSWESLEPGEVVTGPCDNCTCVAG---ILQCQEVPDCPDPGVWSSWGPWEDCSVSCGGGE 3665
Query: 262 E-----CA---CPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCV--SPCART 311
+ CA CP +RTC+ + G CPAG YR+C C +
Sbjct: 3666 QLRSRRCARPPCPGPARQSRTCSTQVCREAG----------CPAGRLYRECQPGEGCPFS 3715
Query: 312 CQSLHINEMC-QERCVDGCSCPEGQLLDEGLCVESTECPCVHS----------------- 353
C + C E C +GC CPEG CV+ ECPCV +
Sbjct: 3716 CAHVTQQVGCFSEGCEEGCHCPEGTFQHRLACVQ--ECPCVLTAWLLQELGATIGDPGQP 3773
Query: 354 ---GKRYPPGTSLSRDCNTCICRNSQWICSNEEC 384
G G +L C C C + + CS ++C
Sbjct: 3774 LGPGDELDSGQTLRTSCGNCSCAHGKLSCSLDDC 3807
Score = 60.1 bits (144), Expect = 3e-08
Identities = 103/474 (21%), Positives = 145/474 (30%), Gaps = 127/474 (26%)
Query: 2210 NHCEHGCPRHCDGNVSSCGDHPSE-GCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFL 2268
N C H C D C P GC CPP +++ +G CVP +C + +
Sbjct: 4680 NQCPHSCADLWDR--VQCLQGPCRPGCRCPPGQLVQDGRCVPISSCRCGLPSANASWELA 4737
Query: 2269 EAWVPDHQPCQICTCLSGRKVNCTTQPCP---------TAKAPT-CGLCEVARLRQNADQ 2318
A CQ CTC++ V C Q CP + AP G E R +
Sbjct: 4738 PAQAV-QLDCQNCTCVNESLV-CPHQECPVLGPWSAWSSCSAPCGGGTMERHRTCEGGPG 4795
Query: 2319 CCP-EYECVCDPVSCDLPPVPHCERG----------------LQP--------------- 2346
P + + C+L P P C G LQP
Sbjct: 4796 VAPCQAQDTEQRQECNLQPCPECPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPGCGC 4855
Query: 2347 ---TLTNPGECRPNFTCACRKEECK-------RVSPPSCPPHRLPTLRKTQC-------- 2388
L + G C P C C + PP + T T+C
Sbjct: 4856 PGGQLLHNGTCVPPTACPCTQHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFS 4915
Query: 2389 CDEYECAC-------------------NCVNSTVSCPLGYLASTATNDCGC-------TT 2422
C +C C+ + +S + C C
Sbjct: 4916 CSLVDCQVPPGETWQQVAPGELGLCEQTCLEMNATKTQSNCSSARASGCVCQPGHFRSQA 4975
Query: 2423 TTCLPDK--VCVHRSTIYPVGQFWEEGCDVCTCTDMEDAVMGLRVAQCSQKPCEDSCRSG 2480
C+P+ C H + G W+E C+ C C C+Q +C G
Sbjct: 4976 GPCVPEDHCECWHLGRPHLPGSEWQEACESCLCLSGRPV--------CTQHCSPLTCAQG 5027
Query: 2481 FTYVLHEGECCGRCLPSA-------CEVVT---GSPRGD--------SQSSWKSVGSQWA 2522
VL G CC C A C+++T +G S S S
Sbjct: 5028 EEMVLEPGSCCPSCRREAPEEQSPSCQLLTELRNFTKGTCYLDQVEVSYCSGYCPSSTHV 5087
Query: 2523 SPENPCLINEC----VRVKEEVFIQQRNVSC--PQLEVPVCPSGFQLSCKTSAC 2570
PE P L ++C R+ E ++ N+ C E V P SC+ S+C
Sbjct: 5088 MPEEPYLQSQCDCCSYRLDPESPVRILNLRCLGGHTEPVVLP--VIHSCQCSSC 5139
Score = 59.3 bits (142), Expect = 5e-08
Identities = 104/433 (24%), Positives = 137/433 (31%), Gaps = 98/433 (22%)
Query: 2209 YNHCEHGCPRHCDGNVSSCGDHPSEGCFCPPDKVMLEGS--CVPEEACTQCIGEDGVQHQ 2266
Y+ C CPR CD V C GC+CPP +V+ CV C+ C+ Q
Sbjct: 3319 YSPCGPPCPRSCDDLVH-CVWRCQPGCYCPPGQVLSSNGAICVQPGHCS-CLDLLTGQRH 3376
Query: 2267 FLEAWVPDHQPCQICTCLSGRKVNCTTQPCPTAKAPTCGLCEVARLRQNADQCCPEYECV 2326
A + C CTCL GR +NCT PCP G C + + C +
Sbjct: 3377 HPGARLARPDGCNHCTCLEGR-LNCTDLPCPVPG----GWCPWSEWTMCSQPCRGQTRSR 3431
Query: 2327 CDPVSCDLPPVPHCERGLQPTLTNPGE---------CRPNFTC----------------- 2360
+C P + G P GE C TC
Sbjct: 3432 SRACACPTP-----QHGGAPCTGEAGEAGAQHQREACPSYATCPVDGAWGPWGPWSPCDM 3486
Query: 2361 ----ACRKEECKRVSPPS----CPPHRLPTLRKTQCCDEYECAC-NCVNSTVSCPLGYLA 2411
+ R C R P CP + +++ C E C +C P G
Sbjct: 3487 CLGQSHRSRACSRPPTPEGGRPCPGNH----TQSRPCQENSTQCTDCGGGQSLHPCGQPC 3542
Query: 2412 STATNDCGCTTTTCLPDKVCVHRSTIYPVGQFWEEGCDV----CTCTDMEDAVMGLRVAQ 2467
+ D + C P V + P+GQ ++G V C C + MG+ Q
Sbjct: 3543 PRSCQDLS-PGSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAHCRC-QYQPGAMGIPENQ 3600
Query: 2468 CSQKPCEDSCRSGFTYVLHEGEC----CGRCLPSA----CEVVTGSPRGDSQSSWKSVGS 2519
R L GE C C A C+ V P SSW
Sbjct: 3601 SRSA----GSRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEVPDCPDPGVWSSW----G 3652
Query: 2520 QWASPENPCLINECVRVKEEVFIQQRNVSCPQLEVPVCPSGFQLS--CKTSAC----CPS 2573
W C E Q R+ C + P CP + S C T C CP+
Sbjct: 3653 PWEDCSVSCGGGE----------QLRSRRCAR---PPCPGPARQSRTCSTQVCREAGCPA 3699
Query: 2574 CR----CERMEAC 2582
R C+ E C
Sbjct: 3700 GRLYRECQPGEGC 3712
Score = 58.9 bits (141), Expect = 7e-08
Identities = 25/65 (38%), Positives = 34/65 (52%), Gaps = 1/65 (1%)
Query: 804 CVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAPGETVKIG-CNTCVCRDRKWNCTDHV 862
CV GC CPPG++ H+ RC+ L CPC + PG + +G C+ CVC + C
Sbjct: 2652 CVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFLLGNCSQCVCEKGELLCQPGG 2711
Query: 863 CDATC 867
C C
Sbjct: 2712 CPLPC 2716
Score = 57.8 bits (138), Expect = 2e-07
Identities = 72/292 (24%), Positives = 100/292 (34%), Gaps = 41/292 (14%)
Query: 614 SCSDG-----RECLCGALASYAAACAGRGVRVA--WREPGRCELNCPKGQVYLQCGT--- 663
SC G R C+ + A C G A +P +C G+VY+
Sbjct: 2570 SCGGGHQSRQRSCVDPPPKNGGAPCPGASQERAPCGLQPCSGGTDCELGRVYVSADLCQK 2629
Query: 664 ----PCNLTCRSLSYPDEECNEACLEGCFCPPGLYMDERGDCVPKAQCPCYYDGEIFQPE 719
PC +C + C+ C+EGC CPPGL + + C+P ++CPC E+ P
Sbjct: 2630 GLVPPCPPSCLDPK-ANRSCSGHCVEGCRCPPGLLLHDT-RCLPLSECPCLVGEELKWPG 2687
Query: 720 DIF-SDHHTMCYCEDGFMHCTMSGVP-------GSLLPDAVLSSPLSHRSKRSLSCRPPM 771
F + + C CE G + C G P S S R++ PP
Sbjct: 2688 VSFLLGNCSQCVCEKGELLCQPGGCPLPCGWSAWSSWAPCDRSCGSGVRARFRSPSNPPA 2747
Query: 772 VKLVCPADNLRAEGLECTKTCQ----NYDLECMSMGCVSGCLCPPGMVRHENRCVALERC 827
P + R E C C + C CL P G +R C
Sbjct: 2748 AWGGAPCEGDRQELQGCHTVCGTEVFGWTPWTSWSSCSQSCLAPGGGPGWRSRS---RLC 2804
Query: 828 PCFHQGKEYAPGE-TVKIGCNTCVCRD-------RKWNCTDHVCDATCSTIG 871
P G PG+ T + C+ VC W+ CD T G
Sbjct: 2805 P--SPGDSSCPGDATQEEPCSPPVCPVPSIWGLWAPWSTCSAPCDGGIQTRG 2854
Score = 57.8 bits (138), Expect = 2e-07
Identities = 41/165 (24%), Positives = 62/165 (37%), Gaps = 29/165 (17%)
Query: 767 CRPPMVKLVC---PADNLRAEG----LECTKTCQN-----YD-LECMSMGCVSGCLCPPG 813
CR P + C P A+ L+C C + +D ++C+ C GC CPPG
Sbjct: 4650 CREPWAQESCNGGPCPECEAQDTVFTLDCANQCPHSCADLWDRVQCLQGPCRPGCRCPPG 4709
Query: 814 MVRHENRCVALERCPC----FHQGKEYAPGETVKIGCNTCVCRDRKWNCTDH-------- 861
+ + RCV + C C + E AP + V++ C C C + C
Sbjct: 4710 QLVQDGRCVPISSCRCGLPSANASWELAPAQAVQLDCQNCTCVNESLVCPHQECPVLGPW 4769
Query: 862 ----VCDATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNP 902
C A C M + T +G + P + Q + C P
Sbjct: 4770 SAWSSCSAPCGGGTMERHRTCEGGPGVAPCQAQDTEQRQECNLQP 4814
Score = 57.4 bits (137), Expect = 2e-07
Identities = 32/92 (34%), Positives = 40/92 (43%), Gaps = 12/92 (13%)
Query: 652 CPK----GQVYLQCGTPCNLTCRSLSY-----PDEECNEACLEGCFCPPGLYMDERGDCV 702
CP G++ Q PC LTC +S PD C GC+CP G + G CV
Sbjct: 1807 CPNATCSGELMFQPCAPCPLTCDDISGQVTCPPDWPCGSP---GCWCPEGQVLGSEGWCV 1863
Query: 703 PKAQCPCYYDGEIFQPEDIFSDHHTMCYCEDG 734
QCPC DG + P +C C+DG
Sbjct: 1864 WPRQCPCLVDGARYWPGQRIKADCQLCICQDG 1895
Score = 56.6 bits (135), Expect = 3e-07
Identities = 27/78 (34%), Positives = 35/78 (44%), Gaps = 1/78 (1%)
Query: 775 VCPADNLRAEGLECTKTCQNYDL-ECMSMGCVSGCLCPPGMVRHENRCVALERCPCFHQG 833
+CP D + + +C + C GC CP GM+ N CV + CPC H+G
Sbjct: 3089 MCPRDKQWLDCAQGPASCAELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQDCPCAHEG 3148
Query: 834 KEYAPGETVKIGCNTCVC 851
Y PG TV C C C
Sbjct: 3149 HLYPPGSTVVRPCENCSC 3166
Score = 56.2 bits (134), Expect = 4e-07
Identities = 71/276 (25%), Positives = 92/276 (33%), Gaps = 73/276 (26%)
Query: 639 RVAWREPGR-CELNCPKGQVYLQCGTPCNL-TCRSLSY-----------------PDEEC 679
R AWR R C NC G + PCNL +C L P E C
Sbjct: 3901 RPAWRSRTRLCLANCTMGDPLQE--RPCNLPSCTELPVCPGPGCGAGNCSWTSWAPWEPC 3958
Query: 680 NEACLEG------CFCPPG----------LYMDERGDCVPKAQCPCYYDGEIFQPEDIFS 723
+ +C G + PPG ER C +A CP + P
Sbjct: 3959 SRSCGVGQQRRLRAYRPPGPGGHWCPNILTAYQERRFCNLRA-CPVPGGWSRWSP----- 4012
Query: 724 DHHTMCYCEDGFMHCTMSGVPGSLLPDAVLSSPLSHRS--------KRSLSCRPPMVKLV 775
+ C S G L SSP S ++ C P +
Sbjct: 4013 -----------WSWCDRSCGGGQSLRSRSCSSPPSKNGGAPCAGERHQARLCNPMPCEAG 4061
Query: 776 CPADNLRAEGLECTKTCQNY--DLE----CMS-MGCVSGCLCPPGMVRHENRCVALERCP 828
CPA E + C C DL+ C C GC CP G + + CV + C
Sbjct: 4062 CPAG---MEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVPIGHCD 4118
Query: 829 CFH-QGKEYAPGETVKIGCNTCVCRDRKWNCTDHVC 863
C QG +APG + CN C C+ + +CT C
Sbjct: 4119 CTDAQGHSWAPGSQHQDACNNCSCQAGQLSCTAQPC 4154
Score = 55.8 bits (133), Expect = 6e-07
Identities = 38/104 (36%), Positives = 45/104 (43%), Gaps = 16/104 (15%)
Query: 774 LVCPADNLRA-EGLE-------CTKTCQNYDLECMSMGCVSGCLCPPGMVRHENR--CVA 823
L CP N A EG E C ++C DL C GC CPPG V N CV
Sbjct: 3304 LPCPVTNCTAIEGAEYSPCGPPCPRSCD--DLVHCVWRCQPGCYCPPGQVLSSNGAICVQ 3361
Query: 824 LERCPCFH--QGKEYAPGETVKI--GCNTCVCRDRKWNCTDHVC 863
C C G+ + PG + GCN C C + + NCTD C
Sbjct: 3362 PGHCSCLDLLTGQRHHPGARLARPDGCNHCTCLEGRLNCTDLPC 3405
Score = 53.5 bits (127), Expect = 3e-06
Identities = 49/174 (28%), Positives = 67/174 (38%), Gaps = 26/174 (14%)
Query: 651 NCP--KGQVYLQCGTPCNLTCRSLSYPDEECNEACLEGCFCPPGLYMDERGD-CVPKAQC 707
NC +G Y CG PC +C L + C C GC+CPPG + G CV C
Sbjct: 3310 NCTAIEGAEYSPCGPPCPRSCDDLVH----CVWRCQPGCYCPPGQVLSSNGAICVQPGHC 3365
Query: 708 PC--YYDGEIFQPEDIFS--DHHTMCYCEDGFMHCT--MSGVPGSLLPDA---VLSSPLS 758
C G+ P + D C C +G ++CT VPG P + + S P
Sbjct: 3366 SCLDLLTGQRHHPGARLARPDGCNHCTCLEGRLNCTDLPCPVPGGWCPWSEWTMCSQPCR 3425
Query: 759 HRSK-RSLSCRPPMVKLVCPADNLRAEGLECTKTCQNYDLECMSMGCVSGCLCP 811
+++ RS +C CP + G CT + C S CP
Sbjct: 3426 GQTRSRSRAC-------ACPTP--QHGGAPCTGEAGEAGAQHQREACPSYATCP 3470
Score = 52.0 bits (123), Expect = 8e-06
Identities = 28/102 (27%), Positives = 45/102 (44%), Gaps = 10/102 (9%)
Query: 296 PAGMEYRQCVSP-----CARTCQSLHINEM---CQERCVDGCSCPEGQLLDE-GLCVEST 346
P G ++Q V+P C +TC ++ + C GC C G + G CV
Sbjct: 4924 PPGETWQQ-VAPGELGLCEQTCLEMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPED 4982
Query: 347 ECPCVHSGKRYPPGTSLSRDCNTCICRNSQWICSNEECPGEC 388
C C H G+ + PG+ C +C+C + + +C+ P C
Sbjct: 4983 HCECWHLGRPHLPGSEWQEACESCLCLSGRPVCTQHCSPLTC 5024
Score = 51.6 bits (122), Expect = 1e-05
Identities = 31/100 (31%), Positives = 46/100 (46%), Gaps = 11/100 (11%)
Query: 1146 YNSCAPACQVTCQHPEPLACPVQCVEGCHAHCPPGKILDELLQTCVDPEDCPVCE-VAGR 1204
Y+ C P C +C + + C +C GC+ CPPG++L CV P C + + G+
Sbjct: 3319 YSPCGPPCPRSCD--DLVHCVWRCQPGCY--CPPGQVLSSNGAICVQPGHCSCLDLLTGQ 3374
Query: 1205 RFASGKKVTLNPSDPEHCQICHCDVVNLTCE--ACQEPGG 1242
R G ++ + P+ C C C L C C PGG
Sbjct: 3375 RHHPGARL----ARPDGCNHCTCLEGRLNCTDLPCPVPGG 3410
Score = 50.8 bits (120), Expect = 2e-05
Identities = 26/85 (30%), Positives = 38/85 (44%), Gaps = 3/85 (3%)
Query: 652 CPKGQVYLQCGTPCNLTCRSLSYPDEECNEACLEGCFCPPGLYMDERGDCVPKAQCPCYY 711
CP+ + +L C +C LS P N+ C GC CP G+ + CVP CPC +
Sbjct: 3090 CPRDKQWLDCAQG-PASCAELSAP-RGTNQTCHPGCHCPSGMLL-LNNVCVPTQDCPCAH 3146
Query: 712 DGEIFQPEDIFSDHHTMCYCEDGFM 736
+G ++ P C C G +
Sbjct: 3147 EGHLYPPGSTVVRPCENCSCVSGLI 3171
Score = 48.9 bits (115), Expect = 7e-05
Identities = 42/142 (29%), Positives = 57/142 (40%), Gaps = 19/142 (13%)
Query: 2164 QQDSCHQEQ----VCEVIASYAHLCRTNGVCVDWRTPDFCAMSCPPSLVYNHCEHGCPRH 2219
+Q CH Q C + H R C P+ +C L++ C CP
Sbjct: 1772 RQRQCHSPQNGGRTCAALPGGLHSTRQTKPCPQDGCPN---ATCSGELMFQPCAP-CPLT 1827
Query: 2220 CD---GNVSSCGDHP--SEGCFCPPDKVM-LEGSCVPEEACTQCIGEDGVQHQFLEAWVP 2273
CD G V+ D P S GC+CP +V+ EG CV C + DG ++ +
Sbjct: 1828 CDDISGQVTCPPDWPCGSPGCWCPEGQVLGSEGWCVWPRQCPCLV--DGARYWPGQRIKA 1885
Query: 2274 DHQPCQICTCLSGRKVNCTTQP 2295
D CQ+C C GR C P
Sbjct: 1886 D---CQLCICQDGRPRRCRLNP 1904
Score = 46.2 bits (108), Expect = 5e-04
Identities = 123/546 (22%), Positives = 165/546 (30%), Gaps = 120/546 (21%)
Query: 2119 PGQTCQPIL-EEQCLVPDSS--HCQVLLLPLFAECH---------KVLAPATFYAICQQ- 2165
PG CQ + E C P+ + H L P C VL CQ+
Sbjct: 1299 PGWHCQVVACVEGCFCPEGTLLHGGACLEPASCPCEWGRNSFPPGSVLQKDCGNCTCQEG 1358
Query: 2166 ------DSCHQEQVCEVIASYAHLCRTNGVCV-------------DWRTPDFCAM-SCPP 2205
D H E++ A LC+ NG CV D + CA C
Sbjct: 1359 QWHCGGDGGHCEELVPACAEGEALCQENGHCVPHGWLCDNQDDCGDGSDEEGCAAPGCGE 1418
Query: 2206 SLVYNHCEHGCPRH--CDGNVSSCGDHPSEGCFCPPDKVM--LEGSCVP-------EEAC 2254
+ H P CD CGD E + P ++ +G C+P C
Sbjct: 1419 GQMTCSSGHCLPLALLCD-RQDDCGDGTDEPSYPCPQGLLACADGRCLPPALLCDGHPDC 1477
Query: 2255 TQCIGEDGVQHQFLEAWVPDHQPCQICTCLSGRKVNCTTQPCPTAKAPTCGLCEVARLRQ 2314
E+ Q VP C TCL ++ CP G C + L
Sbjct: 1478 LDAADEESCLGQV--TCVPGEVSCVDGTCLGAIQLCDGVWDCPDGADEGPGHCPLPSLPT 1535
Query: 2315 NADQCCP-----EYECVCDPVSCDLPPVPHCERGLQPTLTNPGECRPNFTCACRKEEC-- 2367
P + P++ P P C G GEC P ++E+C
Sbjct: 1536 PPASTLPGPSPGSLDTASSPLA-SASPAPPC--GPFEFRCGSGECTPRGWRCDQEEDCAD 1592
Query: 2368 ---KRVSPPSCPPHRLPTLRKTQCCDEYECACNCVNSTVSCPLGYLASTATNDCGCTTTT 2424
+R C PH P R C E C+ V CP G + + CG
Sbjct: 1593 GSDERGCGGPCAPHHAPCARGPHCVSP-EQLCDGVR---QCPDG--SDEGPDACGGLPAL 1646
Query: 2425 CLPDKVCVHRSTIYPVGQFWEEGCDVCTCTDMEDAVMGL----RVAQCSQKPCEDSCRSG 2480
P++ T P ++ C TC + G R Q P E C +
Sbjct: 1647 GGPNR------TGLPCPEY---TCPNGTCIGFQLVCDGQPDCGRPGQVGPSPEEQGCGAW 1697
Query: 2481 FTYVLHEGEC---CG--------RCLPSACEVVTGSPRGDSQS------------SWKSV 2517
+ G C CG RC P V+ P + QS W S
Sbjct: 1698 GPW-SPWGPCSRTCGPWGQGRSRRCSPLGLLVLQNCPGPEHQSQACFTAACPVDGEW-ST 1755
Query: 2518 GSQWASPENPCLINECVRVKEEVFIQQRNVSCPQLEVPVC---PSGFQLSCKTSAC---- 2570
S W+ PC +QR PQ C P G + +T C
Sbjct: 1756 WSPWSVCSEPC---------RGTMTRQRQCHSPQNGGRTCAALPGGLHSTRQTKPCPQDG 1806
Query: 2571 CPSCRC 2576
CP+ C
Sbjct: 1807 CPNATC 1812
Score = 44.7 bits (104), Expect = 0.001
Identities = 82/331 (24%), Positives = 104/331 (31%), Gaps = 77/331 (23%)
Query: 2216 CPRHCDGNVSSCGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLE------ 2269
C + C G S S C CP + G CT GE G QHQ
Sbjct: 3420 CSQPCRGQTRS----RSRACACPTPQ---HGGA----PCTGEAGEAGAQHQREACPSYAT 3468
Query: 2270 -----AWVP--DHQPCQICTCLSGRKVNCTTQPCPTAKAPTCGLCEVAR-LRQNADQC-- 2319
AW P PC +C S R C+ P P P G +R ++N+ QC
Sbjct: 3469 CPVDGAWGPWGPWSPCDMCLGQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQENSTQCTD 3528
Query: 2320 -------------CPEYEC-------VCDPVSCDLPPVPHCERGLQPTLTNPGECRPNFT 2359
CP C VC P S P C G L+ G C P
Sbjct: 3529 CGGGQSLHPCGQPCPR-SCQDLSPGSVCQPGSVGCQPTCGCPLG---QLSQDGLCVPPAH 3584
Query: 2360 CACRKEECKRVSPPSCPPHRLPTLRKTQCCDEYECACN-CVNSTVSCPLGYLASTATNDC 2418
C C+ + P + + + E C N T C G L DC
Sbjct: 3585 CRCQYQPGAMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDNCT--CVAGILQCQEVPDC 3642
Query: 2419 GCTTTTCLPDKVCVHRSTIYPVGQFWEEGCDVCTCTDMEDAVMGLRVAQCSQKPCEDSCR 2478
PD ++ WE+ C V +C E LR +C++ PC R
Sbjct: 3643 --------PD------PGVWSSWGPWED-CSV-SCGGGEQ----LRSRRCARPPCPGPAR 3682
Query: 2479 SG---FTYVLHEGECCGRCLPSACEVVTGSP 2506
T V E C L C+ G P
Sbjct: 3683 QSRTCSTQVCREAGCPAGRLYRECQPGEGCP 3713
Score = 40.8 bits (94), Expect = 0.019
Identities = 34/109 (31%), Positives = 44/109 (40%), Gaps = 20/109 (18%)
Query: 1147 NSCAPACQVTCQHPEPLACPVQ--CVEGCHAHCPPGKILDELLQTCVDPEDCPVCEVAGR 1204
++CA +C C H +P A VQ C GC CP G++L TCV P CP +
Sbjct: 4825 SACATSCPCLCWHLQPGAICVQEPCQPGC--GCPGGQLLHN--GTCVPPTACPCTQ---H 4877
Query: 1205 RFASGKKVTLNPSDPE---------HCQICHCDVVNLTCEA--CQEPGG 1242
G +TL E +C C C +C CQ P G
Sbjct: 4878 SLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDCQVPPG 4926
Score = 40.0 bits (92), Expect = 0.032
Identities = 29/99 (29%), Positives = 38/99 (38%), Gaps = 24/99 (24%)
Query: 2203 CPPSLVYNHCEHGCPRHCDGNVSSCGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGED- 2261
CPPS + C HC EGC CPP ++ + C+P C +GE+
Sbjct: 2635 CPPSCLDPKANRSCSGHC-----------VEGCRCPPGLLLHDTRCLPLSECPCLVGEEL 2683
Query: 2262 ---GVQHQFLEAWVPDHQPCQICTCLSGRKVNCTTQPCP 2297
GV FL C C C G ++ C CP
Sbjct: 2684 KWPGV--SFLLG------NCSQCVCEKG-ELLCQPGGCP 2713
Score = 38.1 bits (87), Expect = 0.12
Identities = 100/416 (24%), Positives = 128/416 (30%), Gaps = 83/416 (19%)
Query: 2287 RKVNCTTQPCPTAKA----PTCGLCEVARLRQNADQCCPEYECVCDPVSCDLPPVPHCER 2342
R +C Q CP A A G C V+ + + + CV P P P +
Sbjct: 2543 RSQSCFVQACPVAGAWAMWEAWGPCSVSCGGGHQSR---QRSCVDPPPKNGGAPCPGASQ 2599
Query: 2343 GLQPTLTNPGECRPNFTCACRK-----EECKRVSPPSCPPHRLPTLRKTQCCD---EYEC 2394
P P C C + + C++ P CPP C D C
Sbjct: 2600 ERAPCGLQP--CSGGTDCELGRVYVSADLCQKGLVPPCPP---------SCLDPKANRSC 2648
Query: 2395 ACNCVNSTVSCPLGYLASTATNDCGCTTTTCLPDKVC---VHRSTIYPVGQFWEEGCDVC 2451
+ +CV CP G L T CLP C V +P F C C
Sbjct: 2649 SGHCVEG-CRCPPGLLLH---------DTRCLPLSECPCLVGEELKWPGVSFLLGNCSQC 2698
Query: 2452 TCTDMEDAVM--GLRV-----AQCSQKPCEDSCRSGFTYVLHE---------GECC--GR 2493
C E G + A S PC+ SC SG G C R
Sbjct: 2699 VCEKGELLCQPGGCPLPCGWSAWSSWAPCDRSCGSGVRARFRSPSNPPAAWGGAPCEGDR 2758
Query: 2494 CLPSACEVVTGSPRGDSQSSWKSVGSQWASPENPCLI---NECVRVKEEVFIQQRNVSCP 2550
C V G+ + W S W+S CL R + + + SCP
Sbjct: 2759 QELQGCHTVCGT-EVFGWTPWTS----WSSCSQSCLAPGGGPGWRSRSRLCPSPGDSSCP 2813
Query: 2551 -------QLEVPVC--PSGFQLSCKTSACCPSCR---CERMEAC--MLNGTVIGPGKTVM 2596
PVC PS + L S C C R +C + G PG
Sbjct: 2814 GDATQEEPCSPPVCPVPSIWGLWAPWSTCSAPCDGGIQTRGRSCSSLAPGDTTCPGPHSQ 2873
Query: 2597 IDVCTTCRCMVQVGVISGFKL--ECRKTTCNPCPLGYKEENNTGECCGRCLPTACT 2650
C T C Q F+ +C + PCP + EC G C P CT
Sbjct: 2874 TRDCNTQPCTAQCPENMLFRSAEQCHQEG-GPCPRLCLTQGPGIECTGFCAP-GCT 2927
Score = 37.0 bits (84), Expect = 0.28
Identities = 40/167 (23%), Positives = 56/167 (33%), Gaps = 59/167 (35%)
Query: 1105 AAYAHVCAQHGKVVTWRTATLCPQSCEERNLRE--------NGYEC-------------- 1142
A + C G+ TW ++C + C R+ G C
Sbjct: 1741 ACFTAACPVDGEWSTWSPWSVCSEPCRGTMTRQRQCHSPQNGGRTCAALPGGLHSTRQTK 1800
Query: 1143 --------------EWRYNSCAP--------ACQVTCQHPEPLACPVQCVEGCHAHCPPG 1180
E + CAP + QVTC P P GC CP G
Sbjct: 1801 PCPQDGCPNATCSGELMFQPCAPCPLTCDDISGQVTCPPDWPCGSP-----GC--WCPEG 1853
Query: 1181 KILDELLQTCVDPEDCPVCEVAGRRFASGKKVTLNPSDPEHCQICHC 1227
++L CV P CP C V G R+ G+++ + CQ+C C
Sbjct: 1854 QVLGS-EGWCVWPRQCP-CLVDGARYWPGQRIKAD------CQLCIC 1892
Score = 37.0 bits (84), Expect = 0.28
Identities = 109/500 (21%), Positives = 144/500 (28%), Gaps = 115/500 (23%)
Query: 2203 CPPSLVYNHCE--HGCP---RHCDGNVSSCGDHPSEGCFCPPDKVMLEGSCVPEEACT-- 2255
CP +Y C+ GCP H V + EGC CP +CV E C
Sbjct: 3697 CPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRLACVQECPCVLT 3756
Query: 2256 --------QCIGEDGV---QHQFLEAWVPDHQPCQICTCLSGRKVNCTTQPCPTAK---- 2300
IG+ G L++ C C+C G K++C+ C A
Sbjct: 3757 AWLLQELGATIGDPGQPLGPGDELDSGQTLRTSCGNCSCAHG-KLSCSLDDCFEADGGFG 3815
Query: 2301 -----APTCGLCEVARLRQNADQCC-------------PEYECVCDPVSC------DLPP 2336
P C R + QC P + C C + P
Sbjct: 3816 PWSPWGPCSRSCGGLGTRTRSRQCVLTMPTLSGQGCRGPRQDLECPSPDCPGAEGSTVEP 3875
Query: 2337 VPHCERGLQP---------TLTNPGECRPNFTCACR--KEECKRVSPPSCPPHRLPTLRK 2385
V G P + T+P RP + R C P P LP+ +
Sbjct: 3876 VTGLPGGWGPWSSWSPCSRSCTDP--ARPAWRSRTRLCLANCTMGDPLQERPCNLPSCTE 3933
Query: 2386 TQCCDEYEC-ACNC--------VNSTVSCPLGYL--------ASTATNDCGCTTTTCLPD 2428
C C A NC + SC +G + C T
Sbjct: 3934 LPVCPGPGCGAGNCSWTSWAPWEPCSRSCGVGQQRRLRAYRPPGPGGHWCPNILTAYQER 3993
Query: 2429 KVCVHRSTIYPVGQFWEEGCDVCTCTDMEDAVMGLRVAQCSQKPCEDSCRSGFTYVLHEG 2488
+ C R+ P G W C LR CS P ++G E
Sbjct: 3994 RFCNLRACPVPGG--WSRWSPWSWCDRSCGGGQSLRSRSCSSPP----SKNGGAPCAGER 4047
Query: 2489 ECCGRCLPSACEVVTGSPRGDSQSSWKSVGSQWASPENPCLINECVRVKEEVFIQQRNVS 2548
C P CE G P G + + N C C ++E + Q V
Sbjct: 4048 HQARLCNPMPCE--AGCP----------AGMEVVTCANRC-PRRCSDLQEGIVCQDDQVC 4094
Query: 2549 CPQLEVPVCPSGFQLSCKTSACCPSCRCERMEACMLNGTVIGPGKTVMIDVCTTCRCMVQ 2608
CP G + C P C+ +A G PG D C C C Q
Sbjct: 4095 QKGCR---CPKGSLE--QDGGCVPIGHCDCTDA---QGHSWAPGSQHQ-DACNNCSC--Q 4143
Query: 2609 VGVISGFKLECRKTTCNPCP 2628
G +S T PCP
Sbjct: 4144 AGQLS--------CTAQPCP 4155
Score = 35.8 bits (81), Expect = 0.61
Identities = 80/350 (22%), Positives = 107/350 (30%), Gaps = 80/350 (22%)
Query: 2314 QNADQCCPEYECVCDPVSCDLPPVPHCERGLQPTLTNPGECRP----NFTCACRKEECKR 2369
++ Q C C D P C + T+T +C TCA
Sbjct: 1736 EHQSQACFTAACPVDGEWSTWSPWSVCSEPCRGTMTRQRQCHSPQNGGRTCAAL------ 1789
Query: 2370 VSPPSCPPHRLPTLRKTQCCDEYECA-CNCVNSTVSCPLGYLASTATNDCGCTTTTCLPD 2428
P L + R+T+ C + C C + P T + G TC PD
Sbjct: 1790 -------PGGLHSTRQTKPCPQDGCPNATCSGELMFQPCAPCPLTCDDISG--QVTCPPD 1840
Query: 2429 KVCVHRSTIYPVGQ-FWEEGCDV----CTC-TDMEDAVMGLRV-AQCSQKPCEDSCRSGF 2481
C P GQ EG V C C D G R+ A C C+D
Sbjct: 1841 WPCGSPGCWCPEGQVLGSEGWCVWPRQCPCLVDGARYWPGQRIKADCQLCICQD------ 1894
Query: 2482 TYVLHEGECCGRCLPSACEVVTGSPRGDSQSSWKSVGSQWASPENPCLINECVRVKEEVF 2541
GR P C + SSW S WA PC + +
Sbjct: 1895 ----------GR--PRRCRLNPDCAVDCGWSSW----SPWAKCLGPC-------GSQSIQ 1931
Query: 2542 IQQRNVSCPQLEVPVCPSGFQLSCK-TSACCPSCRCERMEACMLNGTVIGPGKTVMIDVC 2600
R+ + P+ PSG C+ C+ E E C G V G+ C
Sbjct: 1932 WSFRSSNNPR------PSGRGRQCRGIHRKARRCQTEPCEGCEHQGQVHRVGERWHGGPC 1985
Query: 2601 TTCRCMVQVGVISGFKLECRKTTCNP------CPLGYKEENNTGECCGRC 2644
C+C+ + C+P CP G+ TGE C C
Sbjct: 1986 RVCQCLHNL-----------TAHCSPYCPLGSCPQGWVLVEGTGESCCHC 2024
Score = 34.3 bits (77), Expect = 1.8
Identities = 25/102 (24%), Positives = 35/102 (34%), Gaps = 12/102 (11%)
Query: 2543 QQRNVSCPQLEVPVCPSGFQLSCKTSACCPSCRCERMEACMLNGTVIGPGKTVMIDVCTT 2602
Q + C P C L ++C P +C C L+G + G +D C
Sbjct: 2912 QGPGIECTGFCAPGCTCPPGLFLHNASCLPRSQCP----CQLHGQLYASGAMARLDSCNN 2967
Query: 2603 CRCMVQVGVISGFKLECRKTTCNPCPLGYKEENNTGECCGRC 2644
C C +SG K+ C C P G+ C C
Sbjct: 2968 CTC------VSG-KMACTSERC-PVACGWSPWTLWSLCSCSC 3001
Score = 34.3 bits (77), Expect = 1.8
Identities = 53/228 (23%), Positives = 71/228 (31%), Gaps = 68/228 (29%)
Query: 2396 CNCVNSTVSCPLGYLASTATNDC--GCTT----TTCLPDKVCVHRSTIYPVGQFWEEGCD 2449
CN + CP G T N C C+ C D+VC + P G ++G
Sbjct: 4053 CNPMPCEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVC-QKGCRCPKGSLEQDGGC 4111
Query: 2450 V----CTCTDM-----------EDAVMGLRV----AQCSQKPCEDSCRSGFTYVLHEGEC 2490
V C CTD +DA C+ +PC +++ C
Sbjct: 4112 VPIGHCDCTDAQGHSWAPGSQHQDACNNCSCQAGQLSCTAQPCPPPTHCAWSHWSAWSPC 4171
Query: 2491 CGRCLPSACEVVTGSPRGDSQSSWKSVGSQWASPENPCLINECVRVKEEVFIQQRNVSCP 2550
C PRG S WA EC +EE Q ++ CP
Sbjct: 4172 SHSC----------GPRGQQSRFRSSTSGSWAP--------EC---REE---QSQSQPCP 4207
Query: 2551 QLEVPVCP--------------SGFQLSCKTSACCP-SCRCERMEACM 2583
Q P CP S Q C+ +C P CE E +
Sbjct: 4208 Q---PSCPPLCLQGTRSRTLGDSWLQGECQRCSCTPEGVICEDTECAV 4252
>gi|239755901 PREDICTED: chromosome 12 open reading frame 64 [Homo
sapiens]
Length = 2250
Score = 578 bits (1489), Expect = e-164
Identities = 356/1136 (31%), Positives = 537/1136 (47%), Gaps = 106/1136 (9%)
Query: 28 GRSSTARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQK----------RSFSIIGDFQ 77
G C +G TFDG Y F G CSY+ A C S +G
Sbjct: 57 GNGRDGICKTWGQYHFETFDGIYYYFPGNCSYIFAKDCGDLEPRYTVWVHNSPKCLGSVY 116
Query: 78 NGKRVSLSVYLGEFFDIHLFVNGTVTQGDQRVSMPYASKGLYLETEAGYYKLSGEAYGFV 137
+ R S+S++ +I ++ + G +++P +++E A Y L +GF
Sbjct: 117 SCYR-SISLFFSNQEEIRIYGHEIKKNGIS-LTLPQTIGQIFIEKLADYI-LVKTTFGFS 173
Query: 138 ARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGE 197
DG + LS+ + K+CGLCGN+N DDF+ + T D FANSW++ + +
Sbjct: 174 LAWDGISGIYLKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPD 233
Query: 198 QWCERASPPSSSCNISSGEMQ--KGLWEQCQLLKSTSVFARCHPLVDPEPFVALCEKTLC 255
+ PS N S M + ++ +CQ+L F CH +DP ++A C LC
Sbjct: 234 D-TKCVLTPSDFPNPCSSGMPAFEAIFFKCQILLQFP-FLSCHEYIDPYLYIASCVNDLC 291
Query: 256 ECAGGLECACPALLEYARTCAQEGMVLYGWTDH-SACSPVCPAGMEYRQCVSPCARTCQS 314
+ E C A EYAR C+ G + W D AC+ C +R C+S C TC
Sbjct: 292 KTDDD-ETYCRAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPTCT- 349
Query: 315 LHINEMC---QERCVDGCSCPEGQLLDEGLCVESTECPCVHSGKRYPPGTSLSRDCNTCI 371
+ C C+DGC CP+G ++D G C+ CPC G Y G+ + ++C C+
Sbjct: 350 --FEKQCLGSNLHCLDGCYCPDGLVMDNGTCISLENCPCGFHGLAYSVGSKIEQECTECV 407
Query: 372 CRNSQWICSNEECPGECLVTGQSHFKSFDNRYFTFSGICQYLLARDCQDHSFSIVIETVQ 431
C W C+ ++CP +C V G SHF +FD R+++F G+CQY+L + F+I ++
Sbjct: 408 CVGGVWNCTEQDCPVQCSVVGDSHFTTFDGRHYSFIGMCQYILVKGTGKDKFTITLQKAP 467
Query: 432 CADDRDAVCTRSVTVRLPGLHNSLVKLKHGAGVAMDGQDVQLPLLKGDLRIQHTVTASVR 491
C + VC +S+T+ L N V L G + Q L G + IQ + +
Sbjct: 468 CEQNLGLVCLQSITLILEDDFNKQVTLGRGGQILTSPN--QGFNLNGIVEIQTLSSLFIL 525
Query: 492 L--SYGEDLQMDWDGRGRLLVKLSPVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVEDF 549
L ++G + DG R+ ++L+ + +T GLCG +NGN DDFL+PSG+ E +
Sbjct: 526 LKTTFGLKILFAIDGE-RIYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPSGMIEGTPQLH 584
Query: 550 GNAWKLHGDC-QDLQKQHSDPCALNPRMTRFSEEACAVLTSPTFEACHRAVSPLPYLRNC 608
NAW++ C + DPC +N + ++ C V+ F CH +SP Y + C
Sbjct: 585 ANAWRVSSTCFAPVHVPVVDPCNINQQNIGYAAH-CDVIHQELFAPCHIYISPGLYYQLC 643
Query: 609 RYDVCSCSDGRECLCGALASYAAACAGRGVRVAWR-EPGRCELNCPKGQVYLQCGTPCNL 667
R+D C C G CLC ALA YA C GV + +R + C + C KG +Y C + C
Sbjct: 644 RHDACKC--GSSCLCNALAHYAYLCGQHGVPIDFRTQISFCAVVCQKGMLYHHCSSFCLH 701
Query: 668 TCRSLSYPDEECNEACLEGCFCPPG-LYMDERGDCVPKAQCPCYYDGEIFQPEDIFSDHH 726
+C SLS P E+C++ C EGC CP G Y D CVP C C+Y G ++QP ++
Sbjct: 702 SCISLSSP-EQCSDDCAEGCNCPEGKFYEDTLNFCVPIFHCRCHYRGSVYQPGELIPTPS 760
Query: 727 TMCYCEDGFMHCTMSGVPGSLLPDAVLSSPLSHRSKRSLSCRPPMVKLVCPADNLRAEGL 786
+C C +G + C P ++ + K CR P L A G+
Sbjct: 761 GLCQCSNGTVKCDELATPSAV--------HICPEGKEYFDCR-------FPDPELPAGGV 805
Query: 787 ECTKTCQNYDLECM---SMGCVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAPGETVK 843
C TC N + S C+SGC+C PG
Sbjct: 806 NCETTCANLAMNFTCTPSSPCISGCVCAPG------------------------------ 835
Query: 844 IGCNTCVCRDRKWNCTDHVCDATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPG 903
VCR +NCT + C A C+ G HY +FDGL+Y + +CQ L++ ++
Sbjct: 836 ------VCRRGMFNCTYYPCPAVCTIYGDRHYYSFDGLEYDYISDCQVFLIKS---ADDS 886
Query: 904 TFRILVGNKGCSHPSVKCKKRVTILVEGGEIELFDGEVNVKRP---MKDETHFEVVESGR 960
++ NK C + C K V I V EI L D K+ +++++ +++ ++G
Sbjct: 887 DISVIAQNKKCFDNDIVCSKSVLISVGDTEIYLNDTPYKQKQSGFFLENKSTYQLWKAGY 946
Query: 961 YIILLLG-KALSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSN-LQVEEDP 1018
YI++ K ++++WDR +I + + ++ K+ GLCGNFD +ND+T+SN L+V
Sbjct: 947 YIVVYFPEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNAR 1006
Query: 1019 VDFGNSWKVSSQCADTRKVPLDSSPATCHNNIMKQTMVDSSCRILTSDVFQDCNKLVDPE 1078
V FG+SW + QC + P H N K C IL SD+F C ++D
Sbjct: 1007 V-FGDSWALG-QCESPDET---IKPCEAHQN--KFPYAKKECSILYSDIFASCRNVIDVT 1059
Query: 1079 PYLDVCIYDTCSCESIGDCACFCDTIAAYAHVCAQHGKVVTWRTATLCPQSCEERN 1134
+ C DTC+C GDC C C +IAAYA+ C Q G + WR++T+C CE N
Sbjct: 1060 SFAKNCHEDTCNCNLGGDCECLCTSIAAYAYKCCQEGISIHWRSSTVCSLDCEYYN 1115
Score = 214 bits (546), Expect = 7e-55
Identities = 217/955 (22%), Positives = 358/955 (37%), Gaps = 178/955 (18%)
Query: 1917 VNCDRGLR-PSCPNSQSPVKVEETCGC-RWTCPCVCTGSSTRHIVTFDGQNFKLTGSCSY 1974
+NC + + P C PV+V C W CPC C+ S I+TFDG N L SY
Sbjct: 1406 LNCPKDVEMPDCGFRGRPVQVNSDICCPEWECPCRCSMLSELSIITFDGNNAALYSMASY 1465
Query: 1975 VLFQNKEQDLEVILHNGACSPG-ARQGCMKSIEVKHSALSVELHSDM------EVTVNGR 2027
+L + + ++ H CS A G + + K ++ +H + +V V+
Sbjct: 1466 ILVRIPGEI--IVAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSI 1523
Query: 2028 LVSVPYVGGNMEVNVYGAIMHE-------VRFNHLGHIFTFTPQNNEFQLQLSPKTFASK 2080
+V +P+ + + G++ ++++HL I + F+ LS S
Sbjct: 1524 VVPLPFSSQELSIEDSGSMYVITTPAGLIIKWSHLTGIIDI---HFGFRFNLS-----SY 1575
Query: 2081 TYGLCGICDENGANDFMLRDGTVTTDWKTL---VQEWTVQRPGQTCQPILEEQCLVPDSS 2137
T GLCGIC+E+ +D +++GT+ T+ + + ++ W +++ + C D S
Sbjct: 1576 TEGLCGICNEDPDDDLRMQNGTIITNMEDIGLFIESWEIEKSFEVTMRRPVRNCTEHDCS 1635
Query: 2138 HCQVLL-LPLFAECHKVLAPATFYAICQQDSCHQEQV----CEVIASYAHLCRTNGVCVD 2192
C LL +F CH ++P F C++ + C+ +++Y LC +C+
Sbjct: 1636 QCIDLLNRRIFIPCHDKVSPEDF---CEKMWINYTYFWNYECDALSAYVALCNKFDICIQ 1692
Query: 2193 WRTPDFCAMSCPPSLVYNHCEHGCPRHCDGNVSSCGDHPS-----EGCFCPPDKVMLE-- 2245
WRTPD+C++SCP Y C C N G H S E C C V+
Sbjct: 1693 WRTPDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYG-HTSCLNLREDCVCKVGTVLHRPH 1751
Query: 2246 -GSCVPEEACTQCIGEDGVQHQFLEAWVPDHQPCQICTCLSGRKVNCTTQPCPTAKAPTC 2304
C+PE+ C C + E W C + CL + +P
Sbjct: 1752 SAQCIPEKECA-CTDSEDQPRTAGEIWNGGIDECTLYKCLENGSI-IPIEP--------- 1800
Query: 2305 GLCEVARLRQNADQCCPEYECVCDPVSCDLPPVPHCERGLQPTL--TNPGECRPNFTCAC 2362
CD P P CER + + + C C C
Sbjct: 1801 --------------------------DCDEEPTPVCEREAEVVMGIIDKWTCCSKEVCGC 1834
Query: 2363 RKEECKRVSPPSCPPHRLPTLRKT--QCCDEYECACNCVNSTVSCPLGYLASTATNDCGC 2420
C+ S P+C + + + CC +Y+C C+ + CP
Sbjct: 1835 DTTLCE-TSIPTCTNSQKLIVGHSPLSCCPQYKCECD----PLKCP------------SI 1877
Query: 2421 TTTTCLPDKVCVHRSTIYPVGQFWEEGCDVCT-----CTDMEDAVMGLRVAQ--CSQKPC 2473
+T C D+ + P C+ CT C D E + L C Q C
Sbjct: 1878 STPECREDQFMIQVRQEEPCCFSPFCVCESCTKPVPLCHDGEFLTVDLNSTHFCCPQYYC 1937
Query: 2474 EDSCRSGFTYVLHEGECCGRCLPSACEVVTGSPRGDSQSSWKSVGSQWASPENPCLINEC 2533
C P+ C + + D ++V Q P C EC
Sbjct: 1938 V-------------------CEPNLCPMPLLNCAEDMNLVKENVSGQ-CCPTWHC---EC 1974
Query: 2534 VRVKEEVFIQQRNVSCPQLEVPVCPSG--------FQLSCKTSACCPSCRCERMEACMLN 2585
+C L +P C G FQ C C CE+ + C+
Sbjct: 1975 --------------NCENLVMPTCEVGEFTAIDHNFQSDCG----CIQYLCEKDDVCVFQ 2016
Query: 2586 G-TVIGPGKTVMI----DVCTTCRCMVQVGVISGFK------LECRKTTCNPCPLGYKEE 2634
+V+ PG++++ D C T C+ + +GF + C K C+ +
Sbjct: 2017 EVSVLNPGQSMIKYLEEDFCYTIECLEEKDNHTGFHTLNFTLVNCSKK-CDVHQVYTPSP 2075
Query: 2635 NNTGECCGRCLPTACTIQLRGGQIMTLKRDETLQDGCDTHFCKVNERGEYFWEKRVTGCP 2694
++ G CCG C +C + G + T C T+ C + G + CP
Sbjct: 2076 SDYG-CCGTCKNVSCKFHMENGTSVVYAVGSTWHYNCTTYECVKTDEGAIILNYTMV-CP 2133
Query: 2695 PFDEHKCLAEGGKIMKIPGTCCDTCEEPE--CNDITARLQYVKVGSCKSEVEVDIHYCQG 2752
PF+E +C G + CC C+ E C + + ++ C S+ +++ C G
Sbjct: 2134 PFNETECKMSEGIVKLYNEGCCKICKREERICQKVIIK-SVIRKQDCMSQSPINVASCDG 2192
Query: 2753 KCASKAMYSIDINDVQDQCSCCSPTRTEPMQVALHCT-NGSVVYHEVLNAMECKC 2806
KC S +Y+I+I C CC + V L+C+ NG+ + + + ++C C
Sbjct: 2193 KCPSATIYNINIESHLRFCKCCRENGVRNLSVPLYCSGNGTEIMYTLQEPIDCTC 2247
Score = 213 bits (542), Expect = 2e-54
Identities = 136/474 (28%), Positives = 220/474 (46%), Gaps = 46/474 (9%)
Query: 788 CTKTCQNYDLECM--SMGCVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAPGETVKIG 845
C TC ++ +C+ ++ C+ GC CP G+V C++LE CPC G Y+ G ++
Sbjct: 344 CPPTC-TFEKQCLGSNLHCLDGCYCPDGLVMDNGTCISLENCPCGFHGLAYSVGSKIEQE 402
Query: 846 CNTCVCRDRKWNCTDHVCDATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPGTF 905
C CVC WNCT+ C CS +G +H+ TFDG Y F G CQY+LV+ G+ F
Sbjct: 403 CTECVCVGGVWNCTEQDCPVQCSVVGDSHFTTFDGRHYSFIGMCQYILVK---GTGKDKF 459
Query: 906 RILVGNKGC-SHPSVKCKKRVTILVE---GGEIELFDGEVNVKRPMKDETHFEVVE---- 957
I + C + + C + +T+++E ++ L G + P + +VE
Sbjct: 460 TITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGRGGQILTSPNQGFNLNGIVEIQTL 519
Query: 958 SGRYIILLLGKALSVVWD-RHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEE 1016
S +I+L L +++ I + L ++ + GLCG F+G +D S + +E
Sbjct: 520 SSLFILLKTTFGLKILFAIDGERIYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPSGMIEG 579
Query: 1017 DPVDFGNSWKVSSQCADTRKVPLDSSPATCHNNIMKQTM-VDSSCRILTSDVFQDCNKLV 1075
P N+W+VSS C VP+ P NI +Q + + C ++ ++F C+ +
Sbjct: 580 TPQLHANAWRVSSTCFAPVHVPV-VDPC----NINQQNIGYAAHCDVIHQELFAPCHIYI 634
Query: 1076 DPEPYLDVCIYDTCSCESIGDCACFCDTIAAYAHVCAQHGKVVTWRT-ATLCPQSCEERN 1134
P Y +C +D C C S +C C+ +A YA++C QHG + +RT + C C++
Sbjct: 635 SPGLYYQLCRHDACKCGS----SCLCNALAHYAYLCGQHGVPIDFRTQISFCAVVCQKGM 690
Query: 1135 LRENGYECEWRYNSCAPACQVTC-QHPEPLACPVQCVEGCHAHCPPGKILDELLQTCVDP 1193
L Y+ C+ C +C P C C EGC +CP GK ++ L CV
Sbjct: 691 L----------YHHCSSFCLHSCISLSSPEQCSDDCAEGC--NCPEGKFYEDTLNFCVPI 738
Query: 1194 EDCPVCEVAGRRFASGKKVTLNPSDPEHCQICHCDVVNLTCEACQEPGGLVVPP 1247
C C G + G+ + P +C C + C+ P + + P
Sbjct: 739 FHCR-CHYRGSVYQPGELI------PTPSGLCQCSNGTVKCDELATPSAVHICP 785
Score = 134 bits (337), Expect = 1e-30
Identities = 104/397 (26%), Positives = 168/397 (42%), Gaps = 46/397 (11%)
Query: 1935 KVEETC------GCRWTC-----PCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKEQD 1983
K+E+ C G W C P C+ H TFDG+++ G C Y+L + +D
Sbjct: 398 KIEQECTECVCVGGVWNCTEQDCPVQCSVVGDSHFTTFDGRHYSFIGMCQYILVKGTGKD 457
Query: 1984 -LEVILHNGACSPGARQGCMKSIEVKHSALSVELHSDMEVTVNGRLVSVPYVGGNM---- 2038
+ L C C++SI + L + + + + G++++ P G N+
Sbjct: 458 KFTITLQKAPCEQNLGLVCLQSITL---ILEDDFNKQVTLGRGGQILTSPNQGFNLNGIV 514
Query: 2039 EVNVYGAIMHEVRFNHLGHIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFML 2098
E+ ++ ++ G F +QL+ + +T GLCG + N +DF+
Sbjct: 515 EIQTLSSLFILLKTT-FGLKILFAIDGERIYIQLT-SAWKRRTLGLCGTFNGNIRDDFLS 572
Query: 2099 RDGTVTTDWKTLVQEWTVQRPGQTC---------QPILEEQCLVPDSSHCQVLLLPLFAE 2149
G + + W V TC P Q + ++HC V+ LFA
Sbjct: 573 PSGMIEGTPQLHANAWRVS---STCFAPVHVPVVDPCNINQQNIGYAAHCDVIHQELFAP 629
Query: 2150 CHKVLAPATFYAICQQDSCH--QEQVCEVIASYAHLCRTNGVCVDWRTP-DFCAMSCPPS 2206
CH ++P +Y +C+ D+C +C +A YA+LC +GV +D+RT FCA+ C
Sbjct: 630 CHIYISPGLYYQLCRHDACKCGSSCLCNALAHYAYLCGQHGVPIDFRTQISFCAVVCQKG 689
Query: 2207 LVYNHCEHGCPRHCD--GNVSSCGDHPSEGCFCPPDKVMLE--GSCVPEEACTQCIGEDG 2262
++Y+HC C C + C D +EGC CP K + CVP C +C
Sbjct: 690 MLYHHCSSFCLHSCISLSSPEQCSDDCAEGCNCPEGKFYEDTLNFCVPIFHC-RCHYRGS 748
Query: 2263 VQHQFLEAWVPDHQPCQICTCLSGRKVNCTTQPCPTA 2299
V +P P +C C +G V C P+A
Sbjct: 749 VYQP--GELIP--TPSGLCQCSNG-TVKCDELATPSA 780
Score = 115 bits (289), Expect = 5e-25
Identities = 106/373 (28%), Positives = 149/373 (39%), Gaps = 38/373 (10%)
Query: 1949 VCTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKEQDLE----VILHNGACSPGARQGCMKS 2004
+C H TFDG + G+CSY+ F DLE V +HN G+ C +S
Sbjct: 63 ICKTWGQYHFETFDGIYYYFPGNCSYI-FAKDCGDLEPRYTVWVHNSPKCLGSVYSCYRS 121
Query: 2005 IEVKHSALSVELHSDMEVTVNGRLVSVPYVGGNMEVN-VYGAIMHEVRFNHLGHIFTFTP 2063
I + S E+ NG +++P G + + + I+ + F F+
Sbjct: 122 ISLFFSNQEEIRIYGHEIKKNGISLTLPQTIGQIFIEKLADYILVKTTFG-----FSLAW 176
Query: 2064 QN-NEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTVQRPGQT 2122
+ L+LS + K+ GLCG ++ ++DF++ T D W+VQ P T
Sbjct: 177 DGISGIYLKLS-EDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDT 235
Query: 2123 CQPILEEQCLVPDSS----------HCQVLLLPLFAECHKVLAPATFYAICQQDSC---H 2169
+ P SS CQ+LL F CH+ + P + A C D C
Sbjct: 236 KCVLTPSDFPNPCSSGMPAFEAIFFKCQILLQFPFLSCHEYIDPYLYIASCVNDLCKTDD 295
Query: 2170 QEQVCEVIASYAHLCRTNGVCV-DWRTPDF--CAMSCPPSLVYNHCEHGCPRHCDGNVSS 2226
E C YA C G + DWR DF C C S V+ C CP C
Sbjct: 296 DETYCRAATEYARACSHAGYPIQDWR-DDFPACTDKCDDSFVHRDCISCCPPTCTFEKQC 354
Query: 2227 CGD--HPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWVPDHQPCQICTCL 2284
G H +GC+CP VM G+C+ E C G G+ + Q C C C+
Sbjct: 355 LGSNLHCLDGCYCPDGLVMDNGTCISLENCP--CGFHGLAY---SVGSKIEQECTECVCV 409
Query: 2285 SGRKVNCTTQPCP 2297
G NCT Q CP
Sbjct: 410 GG-VWNCTEQDCP 421
Score = 85.9 bits (211), Expect = 5e-16
Identities = 108/501 (21%), Positives = 173/501 (34%), Gaps = 110/501 (21%)
Query: 301 YRQCVSPCARTCQSLHINEMCQERCVDGCS--CPEGQLLDEGL--CVESTEC-PCVHSGK 355
Y C +PC +TC V+GC CP+ +LDE CV +C P + +
Sbjct: 1281 YEPCATPCFKTCSDPEALACKFLPPVEGCLPYCPKNMILDEVTLKCVYPRDCIPVIPTEP 1340
Query: 356 RY----------------------------PPGTSLS---------RDCNTCICRNSQW- 377
P T L DC+ IC N +W
Sbjct: 1341 TLMPPAKPTVPMFTVWEMITPSDITVFDMLTPTTGLECEPQKFDPVYDCSQYICLNMEWQ 1400
Query: 378 ------------------------------ICSNEECPGECLVTGQSHFKSFDNRYFTFS 407
C ECP C + + +FD
Sbjct: 1401 LYNWSLNCPKDVEMPDCGFRGRPVQVNSDICCPEWECPCRCSMLSELSIITFDGNNAALY 1460
Query: 408 GICQYLLARDCQDHSFSIVIETVQCADDR------DAVCTRSVTVRLPGLHNSLVKLKHG 461
+ Y+L R + IV +C+ ++ +C + + V P +H +V +
Sbjct: 1461 SMASYILVRIPGE---IIVAHIEKCSMNQAPSGRISGLCFKKLNVTTP-IHKIIVN-RLA 1515
Query: 462 AGVAMDGQDVQLPLLKGDLRIQHTVTASVRLSYGEDLQMDWDGRGRLLVKLSPVYAG--- 518
V +D V LP +L I+ + + V ++ L + W L + ++ G
Sbjct: 1516 RKVEVDSIVVPLPFSSQELSIEDSGSMYV-ITTPAGLIIKWSH----LTGIIDIHFGFRF 1570
Query: 519 ----KTCGLCGNYNGNQGDDFLTPSGLAEPRVEDFG---NAWKLHGDCQDLQKQHSDPCA 571
T GLCG N + DD +G +ED G +W++ + ++ C
Sbjct: 1571 NLSSYTEGLCGICNEDPDDDLRMQNGTIITNMEDIGLFIESWEIEKSFEVTMRRPVRNCT 1630
Query: 572 LNPRMTRFSEEACAVLTSPTFEACHRAVSPLPYLRNCRYDVCSCSDGRECLCGALASYAA 631
+ + +L F CH VSP + C + + C AL++Y A
Sbjct: 1631 EHD-----CSQCIDLLNRRIFIPCHDKVSPEDF---CEKMWINYTYFWNYECDALSAYVA 1682
Query: 632 ACAGRGVRVAWREPGRCELNCPKGQVYLQCGTPCNL-TCRSLSYPDEECNEACLEGCFCP 690
C + + WR P C L+CP+G+ Y C PC TC + + E C C
Sbjct: 1683 LCNKFDICIQWRTPDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTSCLNLREDCVCK 1742
Query: 691 PG--LYMDERGDCVPKAQCPC 709
G L+ C+P+ +C C
Sbjct: 1743 VGTVLHRPHSAQCIPEKECAC 1763
Score = 84.7 bits (208), Expect = 1e-15
Identities = 63/271 (23%), Positives = 113/271 (41%), Gaps = 17/271 (6%)
Query: 1944 WTCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKEQ-DLEVILHNGACSPGARQGCM 2002
+ CP VCT RH +FDG + C L ++ + D+ VI N C C
Sbjct: 847 YPCPAVCTIYGDRHYYSFDGLEYDYISDCQVFLIKSADDSDISVIAQNKKCFDNDIV-CS 905
Query: 2003 KSIEVKHSALSVELHSDMEVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHLGHIFTFT 2062
KS+ + + L+ T + S ++ ++ A + V + I
Sbjct: 906 KSVLISVGDTEIYLND----TPYKQKQSGFFLENKSTYQLWKAGYYIVVYFPEKDITILW 961
Query: 2063 PQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTV---QRP 2119
+ +++ P+ + +K GLCG D+ +ND + + + W + + P
Sbjct: 962 DRKTTIHIKVGPQ-WKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGDSWALGQCESP 1020
Query: 2120 GQTCQPILEEQCLVPDSS-HCQVLLLPLFAECHKVLAPATFYAICQQDSCHQ------EQ 2172
+T +P Q P + C +L +FA C V+ +F C +D+C+ E
Sbjct: 1021 DETIKPCEAHQNKFPYAKKECSILYSDIFASCRNVIDVTSFAKNCHEDTCNCNLGGDCEC 1080
Query: 2173 VCEVIASYAHLCRTNGVCVDWRTPDFCAMSC 2203
+C IA+YA+ C G+ + WR+ C++ C
Sbjct: 1081 LCTSIAAYAYKCCQEGISIHWRSSTVCSLDC 1111
Score = 82.0 bits (201), Expect = 7e-15
Identities = 90/341 (26%), Positives = 131/341 (38%), Gaps = 35/341 (10%)
Query: 34 RCSLFGSDFVNTFDGS---MYSFAGYCSYLLAGGCQKRSFS--IIGDFQNGKRVSLSVY- 87
RCS+ + TFDG+ +YS A Y + G + +G+ L
Sbjct: 1440 RCSMLSELSIITFDGNNAALYSMASYILVRIPGEIIVAHIEKCSMNQAPSGRISGLCFKK 1499
Query: 88 LGEFFDIHLFVNGTVTQGDQR----VSMPYASKGLYLETEAGYYKLSGEAYGFVARIDGS 143
L IH + + + + V +P++S+ L +E Y ++ A + +
Sbjct: 1500 LNVTTPIHKIIVNRLARKVEVDSIVVPLPFSSQELSIEDSGSMYVITTPAGLIIKWSHLT 1559
Query: 144 GNFQVLLSDRY--FNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYD---FANSWALSSGEQ 198
G + R+ + T GLCG N +DD Q GT+ ++ D F SW + +
Sbjct: 1560 GIIDIHFGFRFNLSSYTEGLCGICNEDPDDDLRMQNGTIITNMEDIGLFIESWEIEKSFE 1619
Query: 199 WCERASPPSSSCNISSGEMQKGLWEQCQLLKSTSVFARCHPLVDPEPFVALCEKTLCECA 258
R P +C QC L + +F CH V PE F CEK
Sbjct: 1620 VTMRR--PVRNCTEHD-------CSQCIDLLNRRIFIPCHDKVSPEDF---CEKMWINYT 1667
Query: 259 GGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPC-ARTC--QSL 315
C AL Y C + + + W CS CP G EY+ CV PC ARTC Q
Sbjct: 1668 YFWNYECDALSAYVALCNKFDICIQ-WRTPDYCSLSCPEGKEYQPCVRPCEARTCLNQWF 1726
Query: 316 HINEMCQERCVDGCSCPEGQLL---DEGLCVESTECPCVHS 353
+ + C D C C G +L C+ EC C S
Sbjct: 1727 YGHTSCLNLRED-CVCKVGTVLHRPHSAQCIPEKECACTDS 1766
Score = 66.2 bits (160), Expect = 4e-10
Identities = 30/56 (53%), Positives = 33/56 (58%), Gaps = 1/56 (1%)
Query: 1142 CEWRYNSCAPACQVTCQHPEPLACP-VQCVEGCHAHCPPGKILDELLQTCVDPEDC 1196
CEWRY CA C TC PE LAC + VEGC +CP ILDE+ CV P DC
Sbjct: 1277 CEWRYEPCATPCFKTCSDPEALACKFLPPVEGCLPYCPKNMILDEVTLKCVYPRDC 1332
Score = 55.1 bits (131), Expect = 1e-06
Identities = 89/398 (22%), Positives = 141/398 (35%), Gaps = 87/398 (21%)
Query: 839 GETVKIGCNTCVCRDRKWNCTDHVCDATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYC 898
G V++ + C C + C CS + +TFDG Y+LV+
Sbjct: 1421 GRPVQVNSDIC--------CPEWECPCRCSMLSELSIITFDGNNAALYSMASYILVRI-- 1470
Query: 899 GSNPGTFRILVGNKGCSH---PSVK----CKKRVTILVEGGEI-------ELFDGEVNVK 944
PG I+ + CS PS + C K++ + +I ++ + V
Sbjct: 1471 ---PGEI-IVAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVVP 1526
Query: 945 RPMKDETHFEVVESGRYIILLLGKALSVVW-------DRHLSISVVLKQTYQEKVCGLCG 997
P + + +SG ++ L + W D H L +Y E +CG+C
Sbjct: 1527 LPFSSQ-ELSIEDSGSMYVITTPAGLIIKWSHLTGIIDIHFGFRFNLS-SYTEGLCGIC- 1583
Query: 998 NFDGIQNNDLTSSNLQVEEDPVDFG---NSWKVSSQCADTRKVPLDSSPATCHNNIMKQT 1054
N D ++DL N + + D G SW++ T + P+ + C + Q
Sbjct: 1584 NED--PDDDLRMQNGTIITNMEDIGLFIESWEIEKSFEVTMRRPVRN----CTEHDCSQC 1637
Query: 1055 MVDSSCRILTSDVFQDCNKLVDPEPYLDVCIYDTCSCESIGDCACF-----CDTIAAYAH 1109
+ +L +F C+ V PE + CE + + CD ++AY
Sbjct: 1638 I-----DLLNRRIFIPCHDKVSPEDF----------CEKMWINYTYFWNYECDALSAYVA 1682
Query: 1110 VCAQHGKVVTWRTATLCPQSCEERNLRENGYECEWRYNSCAPACQV-TC------QHPEP 1162
+C + + WRT C SC E Y C C+ TC H
Sbjct: 1683 LCNKFDICIQWRTPDYCSLSCPEGK----------EYQPCVRPCEARTCLNQWFYGHTSC 1732
Query: 1163 LACPVQCV--EGCHAHCP-PGKILDELLQTCVDPEDCP 1197
L CV G H P + + E C D ED P
Sbjct: 1733 LNLREDCVCKVGTVLHRPHSAQCIPEKECACTDSEDQP 1770
>gi|239750386 PREDICTED: chromosome 12 open reading frame 64 [Homo
sapiens]
Length = 2250
Score = 578 bits (1489), Expect = e-164
Identities = 356/1136 (31%), Positives = 537/1136 (47%), Gaps = 106/1136 (9%)
Query: 28 GRSSTARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQK----------RSFSIIGDFQ 77
G C +G TFDG Y F G CSY+ A C S +G
Sbjct: 57 GNGRDGICKTWGQYHFETFDGIYYYFPGNCSYIFAKDCGDLEPRYTVWVHNSPKCLGSVY 116
Query: 78 NGKRVSLSVYLGEFFDIHLFVNGTVTQGDQRVSMPYASKGLYLETEAGYYKLSGEAYGFV 137
+ R S+S++ +I ++ + G +++P +++E A Y L +GF
Sbjct: 117 SCYR-SISLFFSNQEEIRIYGHEIKKNGIS-LTLPQTIGQIFIEKLADYI-LVKTTFGFS 173
Query: 138 ARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGE 197
DG + LS+ + K+CGLCGN+N DDF+ + T D FANSW++ + +
Sbjct: 174 LAWDGISGIYLKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPD 233
Query: 198 QWCERASPPSSSCNISSGEMQ--KGLWEQCQLLKSTSVFARCHPLVDPEPFVALCEKTLC 255
+ PS N S M + ++ +CQ+L F CH +DP ++A C LC
Sbjct: 234 D-TKCVLTPSDFPNPCSSGMPAFEAIFFKCQILLQFP-FLSCHEYIDPYLYIASCVNDLC 291
Query: 256 ECAGGLECACPALLEYARTCAQEGMVLYGWTDH-SACSPVCPAGMEYRQCVSPCARTCQS 314
+ E C A EYAR C+ G + W D AC+ C +R C+S C TC
Sbjct: 292 KTDDD-ETYCRAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPTCT- 349
Query: 315 LHINEMC---QERCVDGCSCPEGQLLDEGLCVESTECPCVHSGKRYPPGTSLSRDCNTCI 371
+ C C+DGC CP+G ++D G C+ CPC G Y G+ + ++C C+
Sbjct: 350 --FEKQCLGSNLHCLDGCYCPDGLVMDNGTCISLENCPCGFHGLAYSVGSKIEQECTECV 407
Query: 372 CRNSQWICSNEECPGECLVTGQSHFKSFDNRYFTFSGICQYLLARDCQDHSFSIVIETVQ 431
C W C+ ++CP +C V G SHF +FD R+++F G+CQY+L + F+I ++
Sbjct: 408 CVGGVWNCTEQDCPVQCSVVGDSHFTTFDGRHYSFIGMCQYILVKGTGKDKFTITLQKAP 467
Query: 432 CADDRDAVCTRSVTVRLPGLHNSLVKLKHGAGVAMDGQDVQLPLLKGDLRIQHTVTASVR 491
C + VC +S+T+ L N V L G + Q L G + IQ + +
Sbjct: 468 CEQNLGLVCLQSITLILEDDFNKQVTLGRGGQILTSPN--QGFNLNGIVEIQTLSSLFIL 525
Query: 492 L--SYGEDLQMDWDGRGRLLVKLSPVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVEDF 549
L ++G + DG R+ ++L+ + +T GLCG +NGN DDFL+PSG+ E +
Sbjct: 526 LKTTFGLKILFAIDGE-RIYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPSGMIEGTPQLH 584
Query: 550 GNAWKLHGDC-QDLQKQHSDPCALNPRMTRFSEEACAVLTSPTFEACHRAVSPLPYLRNC 608
NAW++ C + DPC +N + ++ C V+ F CH +SP Y + C
Sbjct: 585 ANAWRVSSTCFAPVHVPVVDPCNINQQNIGYAAH-CDVIHQELFAPCHIYISPGLYYQLC 643
Query: 609 RYDVCSCSDGRECLCGALASYAAACAGRGVRVAWR-EPGRCELNCPKGQVYLQCGTPCNL 667
R+D C C G CLC ALA YA C GV + +R + C + C KG +Y C + C
Sbjct: 644 RHDACKC--GSSCLCNALAHYAYLCGQHGVPIDFRTQISFCAVVCQKGMLYHHCSSFCLH 701
Query: 668 TCRSLSYPDEECNEACLEGCFCPPG-LYMDERGDCVPKAQCPCYYDGEIFQPEDIFSDHH 726
+C SLS P E+C++ C EGC CP G Y D CVP C C+Y G ++QP ++
Sbjct: 702 SCISLSSP-EQCSDDCAEGCNCPEGKFYEDTLNFCVPIFHCRCHYRGSVYQPGELIPTPS 760
Query: 727 TMCYCEDGFMHCTMSGVPGSLLPDAVLSSPLSHRSKRSLSCRPPMVKLVCPADNLRAEGL 786
+C C +G + C P ++ + K CR P L A G+
Sbjct: 761 GLCQCSNGTVKCDELATPSAV--------HICPEGKEYFDCR-------FPDPELPAGGV 805
Query: 787 ECTKTCQNYDLECM---SMGCVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAPGETVK 843
C TC N + S C+SGC+C PG
Sbjct: 806 NCETTCANLAMNFTCTPSSPCISGCVCAPG------------------------------ 835
Query: 844 IGCNTCVCRDRKWNCTDHVCDATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPG 903
VCR +NCT + C A C+ G HY +FDGL+Y + +CQ L++ ++
Sbjct: 836 ------VCRRGMFNCTYYPCPAVCTIYGDRHYYSFDGLEYDYISDCQVFLIKS---ADDS 886
Query: 904 TFRILVGNKGCSHPSVKCKKRVTILVEGGEIELFDGEVNVKRP---MKDETHFEVVESGR 960
++ NK C + C K V I V EI L D K+ +++++ +++ ++G
Sbjct: 887 DISVIAQNKKCFDNDIVCSKSVLISVGDTEIYLNDTPYKQKQSGFFLENKSTYQLWKAGY 946
Query: 961 YIILLLG-KALSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSN-LQVEEDP 1018
YI++ K ++++WDR +I + + ++ K+ GLCGNFD +ND+T+SN L+V
Sbjct: 947 YIVVYFPEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNAR 1006
Query: 1019 VDFGNSWKVSSQCADTRKVPLDSSPATCHNNIMKQTMVDSSCRILTSDVFQDCNKLVDPE 1078
V FG+SW + QC + P H N K C IL SD+F C ++D
Sbjct: 1007 V-FGDSWALG-QCESPDET---IKPCEAHQN--KFPYAKKECSILYSDIFASCRNVIDVT 1059
Query: 1079 PYLDVCIYDTCSCESIGDCACFCDTIAAYAHVCAQHGKVVTWRTATLCPQSCEERN 1134
+ C DTC+C GDC C C +IAAYA+ C Q G + WR++T+C CE N
Sbjct: 1060 SFAKNCHEDTCNCNLGGDCECLCTSIAAYAYKCCQEGISIHWRSSTVCSLDCEYYN 1115
Score = 214 bits (545), Expect = 1e-54
Identities = 216/955 (22%), Positives = 358/955 (37%), Gaps = 178/955 (18%)
Query: 1917 VNCDRGLR-PSCPNSQSPVKVEETCGC-RWTCPCVCTGSSTRHIVTFDGQNFKLTGSCSY 1974
+NC + + P C PV+V C W CPC C+ S I+TFDG N L SY
Sbjct: 1406 LNCPKDVEMPDCGFRGRPVQVNSDICCPEWECPCRCSMLSELSIITFDGNNAALYSMASY 1465
Query: 1975 VLFQNKEQDLEVILHNGACSPG-ARQGCMKSIEVKHSALSVELHSDM------EVTVNGR 2027
+L + + ++ H CS A G + + K ++ +H + +V V+
Sbjct: 1466 ILVRIPGEI--IVAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSI 1523
Query: 2028 LVSVPYVGGNMEVNVYGAIMHE-------VRFNHLGHIFTFTPQNNEFQLQLSPKTFASK 2080
+V +P+ + + G++ ++++HL I + F+ LS S
Sbjct: 1524 VVPLPFSSQELSIEDSGSMYVITTPAGLIIKWSHLTGIIDI---HFGFRFNLS-----SY 1575
Query: 2081 TYGLCGICDENGANDFMLRDGTVTTDWKTL---VQEWTVQRPGQTCQPILEEQCLVPDSS 2137
T GLCGIC+E+ +D +++GT+ T+ + + ++ W +++ + C D S
Sbjct: 1576 TEGLCGICNEDPDDDLRMQNGTIITNMEDIGLFIESWEIEKSFEVTMRRPVRNCTEHDCS 1635
Query: 2138 HCQVLL-LPLFAECHKVLAPATFYAICQQDSCHQEQV----CEVIASYAHLCRTNGVCVD 2192
C LL +F CH ++P F C++ + C+ +++Y LC +C+
Sbjct: 1636 QCIDLLNRRIFIPCHDKVSPEDF---CEKMWINYTYFWNYECDALSAYVALCNKFDICIQ 1692
Query: 2193 WRTPDFCAMSCPPSLVYNHCEHGCPRHCDGNVSSCGDHPS-----EGCFCPPDKVMLE-- 2245
WRTPD+C++SCP Y C C N G H S E C C ++
Sbjct: 1693 WRTPDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYG-HTSCLNLREDCVCKVGTILHRPH 1751
Query: 2246 -GSCVPEEACTQCIGEDGVQHQFLEAWVPDHQPCQICTCLSGRKVNCTTQPCPTAKAPTC 2304
C+PE+ C C + E W C + CL + +P
Sbjct: 1752 SAQCIPEKECA-CTDSEDQPRTAGEIWNGGIDECTLYKCLENGSI-IPIEP--------- 1800
Query: 2305 GLCEVARLRQNADQCCPEYECVCDPVSCDLPPVPHCERGLQPTL--TNPGECRPNFTCAC 2362
CD P P CER + + + C C C
Sbjct: 1801 --------------------------DCDEEPTPVCEREAEVVMGIIDKWTCCSKEVCGC 1834
Query: 2363 RKEECKRVSPPSCPPHRLPTLRKT--QCCDEYECACNCVNSTVSCPLGYLASTATNDCGC 2420
C+ S P+C + + + CC +Y+C C+ + CP
Sbjct: 1835 DTTLCE-TSIPTCTNSQKLIVGHSPLSCCPQYKCECD----PLKCP------------SI 1877
Query: 2421 TTTTCLPDKVCVHRSTIYPVGQFWEEGCDVCT-----CTDMEDAVMGLRVAQ--CSQKPC 2473
+T C D+ + P C+ CT C D E + L C Q C
Sbjct: 1878 STPECREDQFMIQVRQEEPCCFSPFCVCESCTKPVPLCHDGEFLTVDLNSTHFCCPQYYC 1937
Query: 2474 EDSCRSGFTYVLHEGECCGRCLPSACEVVTGSPRGDSQSSWKSVGSQWASPENPCLINEC 2533
C P+ C + + D ++V Q P C EC
Sbjct: 1938 V-------------------CEPNLCPMPLLNCAEDMNLVKENVSGQ-CCPTWHC---EC 1974
Query: 2534 VRVKEEVFIQQRNVSCPQLEVPVCPSG--------FQLSCKTSACCPSCRCERMEACMLN 2585
+C L +P C G FQ C C CE+ + C+
Sbjct: 1975 --------------NCENLVMPTCEVGEFTAIDHNFQSDCG----CIQYLCEKDDVCVFQ 2016
Query: 2586 G-TVIGPGKTVMI----DVCTTCRCMVQVGVISGFK------LECRKTTCNPCPLGYKEE 2634
+V+ PG++++ D C T C+ + +GF + C K C+ +
Sbjct: 2017 EVSVLNPGQSMIKYLEEDFCYTIECLEEKDNHTGFHTLNFTLVNCSKK-CDVHQVYTPSP 2075
Query: 2635 NNTGECCGRCLPTACTIQLRGGQIMTLKRDETLQDGCDTHFCKVNERGEYFWEKRVTGCP 2694
++ G CCG C +C + G + T C T+ C + G + CP
Sbjct: 2076 SDYG-CCGTCKNVSCKFHMENGTSVVYAVGSTWHYNCTTYECVKTDEGAIILNYTMV-CP 2133
Query: 2695 PFDEHKCLAEGGKIMKIPGTCCDTCEEPE--CNDITARLQYVKVGSCKSEVEVDIHYCQG 2752
PF+E +C G + CC C+ E C + + ++ C S+ +++ C G
Sbjct: 2134 PFNETECKMNEGIVKLYNEGCCKICKREERICQKVIIK-SVIRKQDCMSQSPINVASCDG 2192
Query: 2753 KCASKAMYSIDINDVQDQCSCCSPTRTEPMQVALHCT-NGSVVYHEVLNAMECKC 2806
KC S +Y+I+I C CC + V L+C+ NG+ + + + ++C C
Sbjct: 2193 KCPSATIYNINIESHLRFCKCCRENGVRNLSVPLYCSGNGTEIMYTLQEPIDCTC 2247
Score = 213 bits (542), Expect = 2e-54
Identities = 136/474 (28%), Positives = 220/474 (46%), Gaps = 46/474 (9%)
Query: 788 CTKTCQNYDLECM--SMGCVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAPGETVKIG 845
C TC ++ +C+ ++ C+ GC CP G+V C++LE CPC G Y+ G ++
Sbjct: 344 CPPTC-TFEKQCLGSNLHCLDGCYCPDGLVMDNGTCISLENCPCGFHGLAYSVGSKIEQE 402
Query: 846 CNTCVCRDRKWNCTDHVCDATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPGTF 905
C CVC WNCT+ C CS +G +H+ TFDG Y F G CQY+LV+ G+ F
Sbjct: 403 CTECVCVGGVWNCTEQDCPVQCSVVGDSHFTTFDGRHYSFIGMCQYILVK---GTGKDKF 459
Query: 906 RILVGNKGC-SHPSVKCKKRVTILVE---GGEIELFDGEVNVKRPMKDETHFEVVE---- 957
I + C + + C + +T+++E ++ L G + P + +VE
Sbjct: 460 TITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGRGGQILTSPNQGFNLNGIVEIQTL 519
Query: 958 SGRYIILLLGKALSVVWD-RHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEE 1016
S +I+L L +++ I + L ++ + GLCG F+G +D S + +E
Sbjct: 520 SSLFILLKTTFGLKILFAIDGERIYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPSGMIEG 579
Query: 1017 DPVDFGNSWKVSSQCADTRKVPLDSSPATCHNNIMKQTM-VDSSCRILTSDVFQDCNKLV 1075
P N+W+VSS C VP+ P NI +Q + + C ++ ++F C+ +
Sbjct: 580 TPQLHANAWRVSSTCFAPVHVPV-VDPC----NINQQNIGYAAHCDVIHQELFAPCHIYI 634
Query: 1076 DPEPYLDVCIYDTCSCESIGDCACFCDTIAAYAHVCAQHGKVVTWRT-ATLCPQSCEERN 1134
P Y +C +D C C S +C C+ +A YA++C QHG + +RT + C C++
Sbjct: 635 SPGLYYQLCRHDACKCGS----SCLCNALAHYAYLCGQHGVPIDFRTQISFCAVVCQKGM 690
Query: 1135 LRENGYECEWRYNSCAPACQVTC-QHPEPLACPVQCVEGCHAHCPPGKILDELLQTCVDP 1193
L Y+ C+ C +C P C C EGC +CP GK ++ L CV
Sbjct: 691 L----------YHHCSSFCLHSCISLSSPEQCSDDCAEGC--NCPEGKFYEDTLNFCVPI 738
Query: 1194 EDCPVCEVAGRRFASGKKVTLNPSDPEHCQICHCDVVNLTCEACQEPGGLVVPP 1247
C C G + G+ + P +C C + C+ P + + P
Sbjct: 739 FHCR-CHYRGSVYQPGELI------PTPSGLCQCSNGTVKCDELATPSAVHICP 785
Score = 134 bits (337), Expect = 1e-30
Identities = 104/397 (26%), Positives = 168/397 (42%), Gaps = 46/397 (11%)
Query: 1935 KVEETC------GCRWTC-----PCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKEQD 1983
K+E+ C G W C P C+ H TFDG+++ G C Y+L + +D
Sbjct: 398 KIEQECTECVCVGGVWNCTEQDCPVQCSVVGDSHFTTFDGRHYSFIGMCQYILVKGTGKD 457
Query: 1984 -LEVILHNGACSPGARQGCMKSIEVKHSALSVELHSDMEVTVNGRLVSVPYVGGNM---- 2038
+ L C C++SI + L + + + + G++++ P G N+
Sbjct: 458 KFTITLQKAPCEQNLGLVCLQSITL---ILEDDFNKQVTLGRGGQILTSPNQGFNLNGIV 514
Query: 2039 EVNVYGAIMHEVRFNHLGHIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFML 2098
E+ ++ ++ G F +QL+ + +T GLCG + N +DF+
Sbjct: 515 EIQTLSSLFILLKTT-FGLKILFAIDGERIYIQLT-SAWKRRTLGLCGTFNGNIRDDFLS 572
Query: 2099 RDGTVTTDWKTLVQEWTVQRPGQTC---------QPILEEQCLVPDSSHCQVLLLPLFAE 2149
G + + W V TC P Q + ++HC V+ LFA
Sbjct: 573 PSGMIEGTPQLHANAWRVS---STCFAPVHVPVVDPCNINQQNIGYAAHCDVIHQELFAP 629
Query: 2150 CHKVLAPATFYAICQQDSCH--QEQVCEVIASYAHLCRTNGVCVDWRTP-DFCAMSCPPS 2206
CH ++P +Y +C+ D+C +C +A YA+LC +GV +D+RT FCA+ C
Sbjct: 630 CHIYISPGLYYQLCRHDACKCGSSCLCNALAHYAYLCGQHGVPIDFRTQISFCAVVCQKG 689
Query: 2207 LVYNHCEHGCPRHCD--GNVSSCGDHPSEGCFCPPDKVMLE--GSCVPEEACTQCIGEDG 2262
++Y+HC C C + C D +EGC CP K + CVP C +C
Sbjct: 690 MLYHHCSSFCLHSCISLSSPEQCSDDCAEGCNCPEGKFYEDTLNFCVPIFHC-RCHYRGS 748
Query: 2263 VQHQFLEAWVPDHQPCQICTCLSGRKVNCTTQPCPTA 2299
V +P P +C C +G V C P+A
Sbjct: 749 VYQP--GELIP--TPSGLCQCSNG-TVKCDELATPSA 780
Score = 115 bits (289), Expect = 5e-25
Identities = 106/373 (28%), Positives = 149/373 (39%), Gaps = 38/373 (10%)
Query: 1949 VCTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKEQDLE----VILHNGACSPGARQGCMKS 2004
+C H TFDG + G+CSY+ F DLE V +HN G+ C +S
Sbjct: 63 ICKTWGQYHFETFDGIYYYFPGNCSYI-FAKDCGDLEPRYTVWVHNSPKCLGSVYSCYRS 121
Query: 2005 IEVKHSALSVELHSDMEVTVNGRLVSVPYVGGNMEVN-VYGAIMHEVRFNHLGHIFTFTP 2063
I + S E+ NG +++P G + + + I+ + F F+
Sbjct: 122 ISLFFSNQEEIRIYGHEIKKNGISLTLPQTIGQIFIEKLADYILVKTTFG-----FSLAW 176
Query: 2064 QN-NEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTVQRPGQT 2122
+ L+LS + K+ GLCG ++ ++DF++ T D W+VQ P T
Sbjct: 177 DGISGIYLKLS-EDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDT 235
Query: 2123 CQPILEEQCLVPDSS----------HCQVLLLPLFAECHKVLAPATFYAICQQDSC---H 2169
+ P SS CQ+LL F CH+ + P + A C D C
Sbjct: 236 KCVLTPSDFPNPCSSGMPAFEAIFFKCQILLQFPFLSCHEYIDPYLYIASCVNDLCKTDD 295
Query: 2170 QEQVCEVIASYAHLCRTNGVCV-DWRTPDF--CAMSCPPSLVYNHCEHGCPRHCDGNVSS 2226
E C YA C G + DWR DF C C S V+ C CP C
Sbjct: 296 DETYCRAATEYARACSHAGYPIQDWR-DDFPACTDKCDDSFVHRDCISCCPPTCTFEKQC 354
Query: 2227 CGD--HPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWVPDHQPCQICTCL 2284
G H +GC+CP VM G+C+ E C G G+ + Q C C C+
Sbjct: 355 LGSNLHCLDGCYCPDGLVMDNGTCISLENCP--CGFHGLAY---SVGSKIEQECTECVCV 409
Query: 2285 SGRKVNCTTQPCP 2297
G NCT Q CP
Sbjct: 410 GG-VWNCTEQDCP 421
Score = 85.9 bits (211), Expect = 5e-16
Identities = 108/501 (21%), Positives = 173/501 (34%), Gaps = 110/501 (21%)
Query: 301 YRQCVSPCARTCQSLHINEMCQERCVDGCS--CPEGQLLDEGL--CVESTEC-PCVHSGK 355
Y C +PC +TC V+GC CP+ +LDE CV +C P + +
Sbjct: 1281 YEPCATPCFKTCSDPEALACKFLPPVEGCLPYCPKNMILDEVTLKCVYPRDCIPVIPTEP 1340
Query: 356 RY----------------------------PPGTSLS---------RDCNTCICRNSQW- 377
P T L DC+ IC N +W
Sbjct: 1341 TLMPPAKPTVPMFTVWEMITPSDITVFDMLTPTTGLECEPQKFDPVYDCSQYICLNMEWQ 1400
Query: 378 ------------------------------ICSNEECPGECLVTGQSHFKSFDNRYFTFS 407
C ECP C + + +FD
Sbjct: 1401 LYNWSLNCPKDVEMPDCGFRGRPVQVNSDICCPEWECPCRCSMLSELSIITFDGNNAALY 1460
Query: 408 GICQYLLARDCQDHSFSIVIETVQCADDR------DAVCTRSVTVRLPGLHNSLVKLKHG 461
+ Y+L R + IV +C+ ++ +C + + V P +H +V +
Sbjct: 1461 SMASYILVRIPGE---IIVAHIEKCSMNQAPSGRISGLCFKKLNVTTP-IHKIIVN-RLA 1515
Query: 462 AGVAMDGQDVQLPLLKGDLRIQHTVTASVRLSYGEDLQMDWDGRGRLLVKLSPVYAG--- 518
V +D V LP +L I+ + + V ++ L + W L + ++ G
Sbjct: 1516 RKVEVDSIVVPLPFSSQELSIEDSGSMYV-ITTPAGLIIKWSH----LTGIIDIHFGFRF 1570
Query: 519 ----KTCGLCGNYNGNQGDDFLTPSGLAEPRVEDFG---NAWKLHGDCQDLQKQHSDPCA 571
T GLCG N + DD +G +ED G +W++ + ++ C
Sbjct: 1571 NLSSYTEGLCGICNEDPDDDLRMQNGTIITNMEDIGLFIESWEIEKSFEVTMRRPVRNCT 1630
Query: 572 LNPRMTRFSEEACAVLTSPTFEACHRAVSPLPYLRNCRYDVCSCSDGRECLCGALASYAA 631
+ + +L F CH VSP + C + + C AL++Y A
Sbjct: 1631 EHD-----CSQCIDLLNRRIFIPCHDKVSPEDF---CEKMWINYTYFWNYECDALSAYVA 1682
Query: 632 ACAGRGVRVAWREPGRCELNCPKGQVYLQCGTPCNL-TCRSLSYPDEECNEACLEGCFCP 690
C + + WR P C L+CP+G+ Y C PC TC + + E C C
Sbjct: 1683 LCNKFDICIQWRTPDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTSCLNLREDCVCK 1742
Query: 691 PG--LYMDERGDCVPKAQCPC 709
G L+ C+P+ +C C
Sbjct: 1743 VGTILHRPHSAQCIPEKECAC 1763
Score = 84.7 bits (208), Expect = 1e-15
Identities = 63/271 (23%), Positives = 113/271 (41%), Gaps = 17/271 (6%)
Query: 1944 WTCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKEQ-DLEVILHNGACSPGARQGCM 2002
+ CP VCT RH +FDG + C L ++ + D+ VI N C C
Sbjct: 847 YPCPAVCTIYGDRHYYSFDGLEYDYISDCQVFLIKSADDSDISVIAQNKKCFDNDIV-CS 905
Query: 2003 KSIEVKHSALSVELHSDMEVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHLGHIFTFT 2062
KS+ + + L+ T + S ++ ++ A + V + I
Sbjct: 906 KSVLISVGDTEIYLND----TPYKQKQSGFFLENKSTYQLWKAGYYIVVYFPEKDITILW 961
Query: 2063 PQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTV---QRP 2119
+ +++ P+ + +K GLCG D+ +ND + + + W + + P
Sbjct: 962 DRKTTIHIKVGPQ-WKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGDSWALGQCESP 1020
Query: 2120 GQTCQPILEEQCLVPDSS-HCQVLLLPLFAECHKVLAPATFYAICQQDSCHQ------EQ 2172
+T +P Q P + C +L +FA C V+ +F C +D+C+ E
Sbjct: 1021 DETIKPCEAHQNKFPYAKKECSILYSDIFASCRNVIDVTSFAKNCHEDTCNCNLGGDCEC 1080
Query: 2173 VCEVIASYAHLCRTNGVCVDWRTPDFCAMSC 2203
+C IA+YA+ C G+ + WR+ C++ C
Sbjct: 1081 LCTSIAAYAYKCCQEGISIHWRSSTVCSLDC 1111
Score = 82.4 bits (202), Expect = 6e-15
Identities = 90/341 (26%), Positives = 131/341 (38%), Gaps = 35/341 (10%)
Query: 34 RCSLFGSDFVNTFDGS---MYSFAGYCSYLLAGGCQKRSFS--IIGDFQNGKRVSLSVY- 87
RCS+ + TFDG+ +YS A Y + G + +G+ L
Sbjct: 1440 RCSMLSELSIITFDGNNAALYSMASYILVRIPGEIIVAHIEKCSMNQAPSGRISGLCFKK 1499
Query: 88 LGEFFDIHLFVNGTVTQGDQR----VSMPYASKGLYLETEAGYYKLSGEAYGFVARIDGS 143
L IH + + + + V +P++S+ L +E Y ++ A + +
Sbjct: 1500 LNVTTPIHKIIVNRLARKVEVDSIVVPLPFSSQELSIEDSGSMYVITTPAGLIIKWSHLT 1559
Query: 144 GNFQVLLSDRY--FNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYD---FANSWALSSGEQ 198
G + R+ + T GLCG N +DD Q GT+ ++ D F SW + +
Sbjct: 1560 GIIDIHFGFRFNLSSYTEGLCGICNEDPDDDLRMQNGTIITNMEDIGLFIESWEIEKSFE 1619
Query: 199 WCERASPPSSSCNISSGEMQKGLWEQCQLLKSTSVFARCHPLVDPEPFVALCEKTLCECA 258
R P +C QC L + +F CH V PE F CEK
Sbjct: 1620 VTMRR--PVRNCTEHD-------CSQCIDLLNRRIFIPCHDKVSPEDF---CEKMWINYT 1667
Query: 259 GGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPC-ARTC--QSL 315
C AL Y C + + + W CS CP G EY+ CV PC ARTC Q
Sbjct: 1668 YFWNYECDALSAYVALCNKFDICIQ-WRTPDYCSLSCPEGKEYQPCVRPCEARTCLNQWF 1726
Query: 316 HINEMCQERCVDGCSCPEGQLL---DEGLCVESTECPCVHS 353
+ + C D C C G +L C+ EC C S
Sbjct: 1727 YGHTSCLNLRED-CVCKVGTILHRPHSAQCIPEKECACTDS 1766
Score = 66.2 bits (160), Expect = 4e-10
Identities = 30/56 (53%), Positives = 33/56 (58%), Gaps = 1/56 (1%)
Query: 1142 CEWRYNSCAPACQVTCQHPEPLACP-VQCVEGCHAHCPPGKILDELLQTCVDPEDC 1196
CEWRY CA C TC PE LAC + VEGC +CP ILDE+ CV P DC
Sbjct: 1277 CEWRYEPCATPCFKTCSDPEALACKFLPPVEGCLPYCPKNMILDEVTLKCVYPRDC 1332
Score = 55.1 bits (131), Expect = 1e-06
Identities = 89/398 (22%), Positives = 141/398 (35%), Gaps = 87/398 (21%)
Query: 839 GETVKIGCNTCVCRDRKWNCTDHVCDATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYC 898
G V++ + C C + C CS + +TFDG Y+LV+
Sbjct: 1421 GRPVQVNSDIC--------CPEWECPCRCSMLSELSIITFDGNNAALYSMASYILVRI-- 1470
Query: 899 GSNPGTFRILVGNKGCSH---PSVK----CKKRVTILVEGGEI-------ELFDGEVNVK 944
PG I+ + CS PS + C K++ + +I ++ + V
Sbjct: 1471 ---PGEI-IVAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVVP 1526
Query: 945 RPMKDETHFEVVESGRYIILLLGKALSVVW-------DRHLSISVVLKQTYQEKVCGLCG 997
P + + +SG ++ L + W D H L +Y E +CG+C
Sbjct: 1527 LPFSSQ-ELSIEDSGSMYVITTPAGLIIKWSHLTGIIDIHFGFRFNLS-SYTEGLCGIC- 1583
Query: 998 NFDGIQNNDLTSSNLQVEEDPVDFG---NSWKVSSQCADTRKVPLDSSPATCHNNIMKQT 1054
N D ++DL N + + D G SW++ T + P+ + C + Q
Sbjct: 1584 NED--PDDDLRMQNGTIITNMEDIGLFIESWEIEKSFEVTMRRPVRN----CTEHDCSQC 1637
Query: 1055 MVDSSCRILTSDVFQDCNKLVDPEPYLDVCIYDTCSCESIGDCACF-----CDTIAAYAH 1109
+ +L +F C+ V PE + CE + + CD ++AY
Sbjct: 1638 I-----DLLNRRIFIPCHDKVSPEDF----------CEKMWINYTYFWNYECDALSAYVA 1682
Query: 1110 VCAQHGKVVTWRTATLCPQSCEERNLRENGYECEWRYNSCAPACQV-TC------QHPEP 1162
+C + + WRT C SC E Y C C+ TC H
Sbjct: 1683 LCNKFDICIQWRTPDYCSLSCPEGK----------EYQPCVRPCEARTCLNQWFYGHTSC 1732
Query: 1163 LACPVQCV--EGCHAHCP-PGKILDELLQTCVDPEDCP 1197
L CV G H P + + E C D ED P
Sbjct: 1733 LNLREDCVCKVGTILHRPHSAQCIPEKECACTDSEDQP 1770
>gi|239744688 PREDICTED: hypothetical protein LOC283310 [Homo sapiens]
Length = 2250
Score = 578 bits (1489), Expect = e-164
Identities = 356/1136 (31%), Positives = 537/1136 (47%), Gaps = 106/1136 (9%)
Query: 28 GRSSTARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQK----------RSFSIIGDFQ 77
G C +G TFDG Y F G CSY+ A C S +G
Sbjct: 57 GNGRDGICKTWGQYHFETFDGIYYYFPGNCSYIFAKDCGDLEPRYTVWVHNSPKCLGSVY 116
Query: 78 NGKRVSLSVYLGEFFDIHLFVNGTVTQGDQRVSMPYASKGLYLETEAGYYKLSGEAYGFV 137
+ R S+S++ +I ++ + G +++P +++E A Y L +GF
Sbjct: 117 SCYR-SISLFFSNQEEIRIYGHEIKKNGIS-LTLPQTIGQIFIEKLADYI-LVKTTFGFS 173
Query: 138 ARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGE 197
DG + LS+ + K+CGLCGN+N DDF+ + T D FANSW++ + +
Sbjct: 174 LAWDGISGIYLKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPD 233
Query: 198 QWCERASPPSSSCNISSGEMQ--KGLWEQCQLLKSTSVFARCHPLVDPEPFVALCEKTLC 255
+ PS N S M + ++ +CQ+L F CH +DP ++A C LC
Sbjct: 234 D-TKCVLTPSDFPNPCSSGMPAFEAIFFKCQILLQFP-FLSCHEYIDPYLYIASCVNDLC 291
Query: 256 ECAGGLECACPALLEYARTCAQEGMVLYGWTDH-SACSPVCPAGMEYRQCVSPCARTCQS 314
+ E C A EYAR C+ G + W D AC+ C +R C+S C TC
Sbjct: 292 KTDDD-ETYCRAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPTCT- 349
Query: 315 LHINEMC---QERCVDGCSCPEGQLLDEGLCVESTECPCVHSGKRYPPGTSLSRDCNTCI 371
+ C C+DGC CP+G ++D G C+ CPC G Y G+ + ++C C+
Sbjct: 350 --FEKQCLGSNLHCLDGCYCPDGLVMDNGTCISLENCPCGFHGLAYSVGSKIEQECTECV 407
Query: 372 CRNSQWICSNEECPGECLVTGQSHFKSFDNRYFTFSGICQYLLARDCQDHSFSIVIETVQ 431
C W C+ ++CP +C V G SHF +FD R+++F G+CQY+L + F+I ++
Sbjct: 408 CVGGVWNCTEQDCPVQCSVVGDSHFTTFDGRHYSFIGMCQYILVKGTGKDKFTITLQKAP 467
Query: 432 CADDRDAVCTRSVTVRLPGLHNSLVKLKHGAGVAMDGQDVQLPLLKGDLRIQHTVTASVR 491
C + VC +S+T+ L N V L G + Q L G + IQ + +
Sbjct: 468 CEQNLGLVCLQSITLILEDDFNKQVTLGRGGQILTSPN--QGFNLNGIVEIQTLSSLFIL 525
Query: 492 L--SYGEDLQMDWDGRGRLLVKLSPVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVEDF 549
L ++G + DG R+ ++L+ + +T GLCG +NGN DDFL+PSG+ E +
Sbjct: 526 LKTTFGLKILFAIDGE-RIYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPSGMIEGTPQLH 584
Query: 550 GNAWKLHGDC-QDLQKQHSDPCALNPRMTRFSEEACAVLTSPTFEACHRAVSPLPYLRNC 608
NAW++ C + DPC +N + ++ C V+ F CH +SP Y + C
Sbjct: 585 ANAWRVSSTCFAPVHVPVVDPCNINQQNIGYAAH-CDVIHQELFAPCHIYISPGLYYQLC 643
Query: 609 RYDVCSCSDGRECLCGALASYAAACAGRGVRVAWR-EPGRCELNCPKGQVYLQCGTPCNL 667
R+D C C G CLC ALA YA C GV + +R + C + C KG +Y C + C
Sbjct: 644 RHDACKC--GSSCLCNALAHYAYLCGQHGVPIDFRTQISFCAVVCQKGMLYHHCSSFCLH 701
Query: 668 TCRSLSYPDEECNEACLEGCFCPPG-LYMDERGDCVPKAQCPCYYDGEIFQPEDIFSDHH 726
+C SLS P E+C++ C EGC CP G Y D CVP C C+Y G ++QP ++
Sbjct: 702 SCISLSSP-EQCSDDCAEGCNCPEGKFYEDTLNFCVPIFHCRCHYRGSVYQPGELIPTPS 760
Query: 727 TMCYCEDGFMHCTMSGVPGSLLPDAVLSSPLSHRSKRSLSCRPPMVKLVCPADNLRAEGL 786
+C C +G + C P ++ + K CR P L A G+
Sbjct: 761 GLCQCSNGTVKCDELATPSAV--------HICPEGKEYFDCR-------FPDPELPAGGV 805
Query: 787 ECTKTCQNYDLECM---SMGCVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAPGETVK 843
C TC N + S C+SGC+C PG
Sbjct: 806 NCETTCANLAMNFTCTPSSPCISGCVCAPG------------------------------ 835
Query: 844 IGCNTCVCRDRKWNCTDHVCDATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPG 903
VCR +NCT + C A C+ G HY +FDGL+Y + +CQ L++ ++
Sbjct: 836 ------VCRRGMFNCTYYPCPAVCTIYGDRHYYSFDGLEYDYISDCQVFLIKS---ADDS 886
Query: 904 TFRILVGNKGCSHPSVKCKKRVTILVEGGEIELFDGEVNVKRP---MKDETHFEVVESGR 960
++ NK C + C K V I V EI L D K+ +++++ +++ ++G
Sbjct: 887 DISVIAQNKKCFDNDIVCSKSVLISVGDTEIYLNDTPYKQKQSGFFLENKSTYQLWKAGY 946
Query: 961 YIILLLG-KALSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSN-LQVEEDP 1018
YI++ K ++++WDR +I + + ++ K+ GLCGNFD +ND+T+SN L+V
Sbjct: 947 YIVVYFPEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNAR 1006
Query: 1019 VDFGNSWKVSSQCADTRKVPLDSSPATCHNNIMKQTMVDSSCRILTSDVFQDCNKLVDPE 1078
V FG+SW + QC + P H N K C IL SD+F C ++D
Sbjct: 1007 V-FGDSWALG-QCESPDET---IKPCEAHQN--KFPYAKKECSILYSDIFASCRNVIDVT 1059
Query: 1079 PYLDVCIYDTCSCESIGDCACFCDTIAAYAHVCAQHGKVVTWRTATLCPQSCEERN 1134
+ C DTC+C GDC C C +IAAYA+ C Q G + WR++T+C CE N
Sbjct: 1060 SFAKNCHEDTCNCNLGGDCECLCTSIAAYAYKCCQEGISIHWRSSTVCSLDCEYYN 1115
Score = 213 bits (542), Expect = 2e-54
Identities = 136/474 (28%), Positives = 220/474 (46%), Gaps = 46/474 (9%)
Query: 788 CTKTCQNYDLECM--SMGCVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAPGETVKIG 845
C TC ++ +C+ ++ C+ GC CP G+V C++LE CPC G Y+ G ++
Sbjct: 344 CPPTC-TFEKQCLGSNLHCLDGCYCPDGLVMDNGTCISLENCPCGFHGLAYSVGSKIEQE 402
Query: 846 CNTCVCRDRKWNCTDHVCDATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPGTF 905
C CVC WNCT+ C CS +G +H+ TFDG Y F G CQY+LV+ G+ F
Sbjct: 403 CTECVCVGGVWNCTEQDCPVQCSVVGDSHFTTFDGRHYSFIGMCQYILVK---GTGKDKF 459
Query: 906 RILVGNKGC-SHPSVKCKKRVTILVE---GGEIELFDGEVNVKRPMKDETHFEVVE---- 957
I + C + + C + +T+++E ++ L G + P + +VE
Sbjct: 460 TITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGRGGQILTSPNQGFNLNGIVEIQTL 519
Query: 958 SGRYIILLLGKALSVVWD-RHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEE 1016
S +I+L L +++ I + L ++ + GLCG F+G +D S + +E
Sbjct: 520 SSLFILLKTTFGLKILFAIDGERIYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPSGMIEG 579
Query: 1017 DPVDFGNSWKVSSQCADTRKVPLDSSPATCHNNIMKQTM-VDSSCRILTSDVFQDCNKLV 1075
P N+W+VSS C VP+ P NI +Q + + C ++ ++F C+ +
Sbjct: 580 TPQLHANAWRVSSTCFAPVHVPV-VDPC----NINQQNIGYAAHCDVIHQELFAPCHIYI 634
Query: 1076 DPEPYLDVCIYDTCSCESIGDCACFCDTIAAYAHVCAQHGKVVTWRT-ATLCPQSCEERN 1134
P Y +C +D C C S +C C+ +A YA++C QHG + +RT + C C++
Sbjct: 635 SPGLYYQLCRHDACKCGS----SCLCNALAHYAYLCGQHGVPIDFRTQISFCAVVCQKGM 690
Query: 1135 LRENGYECEWRYNSCAPACQVTC-QHPEPLACPVQCVEGCHAHCPPGKILDELLQTCVDP 1193
L Y+ C+ C +C P C C EGC +CP GK ++ L CV
Sbjct: 691 L----------YHHCSSFCLHSCISLSSPEQCSDDCAEGC--NCPEGKFYEDTLNFCVPI 738
Query: 1194 EDCPVCEVAGRRFASGKKVTLNPSDPEHCQICHCDVVNLTCEACQEPGGLVVPP 1247
C C G + G+ + P +C C + C+ P + + P
Sbjct: 739 FHCR-CHYRGSVYQPGELI------PTPSGLCQCSNGTVKCDELATPSAVHICP 785
Score = 212 bits (539), Expect = 5e-54
Identities = 215/955 (22%), Positives = 357/955 (37%), Gaps = 178/955 (18%)
Query: 1917 VNCDRGLR-PSCPNSQSPVKVEETCGC-RWTCPCVCTGSSTRHIVTFDGQNFKLTGSCSY 1974
+NC + + P C PV+V C W CPC C+ S I+TFDG N L SY
Sbjct: 1406 LNCPKDVEMPDCGFRGRPVQVNSDICCPEWECPCRCSMLSELSIITFDGNNAALYSMASY 1465
Query: 1975 VLFQNKEQDLEVILHNGACSPG-ARQGCMKSIEVKHSALSVELHSDM------EVTVNGR 2027
+L + + ++ H CS A G + + K ++ +H + +V V+
Sbjct: 1466 ILVRIPGEI--IVAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSI 1523
Query: 2028 LVSVPYVGGNMEVNVYGAIMHE-------VRFNHLGHIFTFTPQNNEFQLQLSPKTFASK 2080
+V +P+ + + G++ ++++HL I + F+ LS S
Sbjct: 1524 VVPLPFSSQELSIEDSGSMYVITTPAGLIIKWSHLTGIIDI---HFGFRFNLS-----SY 1575
Query: 2081 TYGLCGICDENGANDFMLRDGTVTTDWKTL---VQEWTVQRPGQTCQPILEEQCLVPDSS 2137
T GLCGIC+E+ +D +++GT+ T+ + + ++ W +++ + C D S
Sbjct: 1576 TEGLCGICNEDPDDDLRMQNGTIITNMEDIGLFIESWEIEKSFEVTMRRPVRNCTEHDCS 1635
Query: 2138 HCQVLL-LPLFAECHKVLAPATFYAICQQDSCHQEQV----CEVIASYAHLCRTNGVCVD 2192
C LL +F CH ++P F C++ + C+ +++Y LC +C+
Sbjct: 1636 QCIDLLNRRIFIPCHDKVSPEDF---CEKMWINYTYFWNYECDALSAYVALCNKFDICIQ 1692
Query: 2193 WRTPDFCAMSCPPSLVYNHCEHGCPRHCDGNVSSCGDHPS-----EGCFCPPDKVMLE-- 2245
WRTPD+C++SCP Y C C N G H S E C C ++
Sbjct: 1693 WRTPDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYG-HTSCLNLREDCVCKVGTILHRPH 1751
Query: 2246 -GSCVPEEACTQCIGEDGVQHQFLEAWVPDHQPCQICTCLSGRKVNCTTQPCPTAKAPTC 2304
C+PE+ C C + E W C + CL + +P
Sbjct: 1752 SAQCIPEKECA-CTDSEDQPRTAGEIWNGGIDECTLYKCLENGSI-IPIEP--------- 1800
Query: 2305 GLCEVARLRQNADQCCPEYECVCDPVSCDLPPVPHCERGLQPTL--TNPGECRPNFTCAC 2362
CD P P CER + + + C C C
Sbjct: 1801 --------------------------DCDEEPTPVCEREAEVVMGIIDKWTCCSKEVCGC 1834
Query: 2363 RKEECKRVSPPSCPPHRLPTLRKT--QCCDEYECACNCVNSTVSCPLGYLASTATNDCGC 2420
C+ S P+C + + + CC +Y+C C+ + CP
Sbjct: 1835 DTTLCE-TSIPTCTNSQKLIVGHSPLSCCPQYKCECD----PLKCP------------SI 1877
Query: 2421 TTTTCLPDKVCVHRSTIYPVGQFWEEGCDVCT-----CTDMEDAVMGLRVAQ--CSQKPC 2473
+T C D+ + P C+ CT C D E + L C Q C
Sbjct: 1878 STPECREDQFMIQVRQEEPCCFSPFCVCESCTKPVPLCHDGEFLTVDLNSTHFCCPQYYC 1937
Query: 2474 EDSCRSGFTYVLHEGECCGRCLPSACEVVTGSPRGDSQSSWKSVGSQWASPENPCLINEC 2533
C P+ C + + D ++V Q P C EC
Sbjct: 1938 V-------------------CEPNLCPMPLLNCAEDMNLVKENVSGQ-CCPTWHC---EC 1974
Query: 2534 VRVKEEVFIQQRNVSCPQLEVPVCPSG--------FQLSCKTSACCPSCRCERMEACMLN 2585
+C L +P C G FQ C C CE+ + C+
Sbjct: 1975 --------------NCENLIMPTCEVGEFTAIDHNFQSDCG----CIQYLCEKDDVCVFQ 2016
Query: 2586 G-TVIGPGKTVMI----DVCTTCRCMVQVGVISGFK------LECRKTTCNPCPLGYKEE 2634
+V+ PG++++ D C C+ + +GF + C K C+ +
Sbjct: 2017 EVSVLNPGQSMIKYLEEDFCYAIECLEEKDNHTGFHTLNFTLVNCSKK-CDVHQVYTPSP 2075
Query: 2635 NNTGECCGRCLPTACTIQLRGGQIMTLKRDETLQDGCDTHFCKVNERGEYFWEKRVTGCP 2694
++ G CCG C +C + G + T C T+ C + G + CP
Sbjct: 2076 SDYG-CCGTCKNVSCKFHMENGTSVVYAVGSTWHYNCTTYECVKTDEGAIILNYTMV-CP 2133
Query: 2695 PFDEHKCLAEGGKIMKIPGTCCDTCEEPE--CNDITARLQYVKVGSCKSEVEVDIHYCQG 2752
PF+E +C G + CC C+ E C + + ++ C S+ +++ C G
Sbjct: 2134 PFNETECKMNEGIVKLYNEGCCKICKREERICQKVIIK-SVIRKQDCMSQSPINVASCDG 2192
Query: 2753 KCASKAMYSIDINDVQDQCSCCSPTRTEPMQVALHCT-NGSVVYHEVLNAMECKC 2806
KC S +Y+I+I C CC + V L+C+ NG+ + + + ++C C
Sbjct: 2193 KCPSATIYNINIESHLRFCKCCRENGVRNLSVPLYCSGNGTEIMYTLQEPIDCTC 2247
Score = 134 bits (337), Expect = 1e-30
Identities = 104/397 (26%), Positives = 168/397 (42%), Gaps = 46/397 (11%)
Query: 1935 KVEETC------GCRWTC-----PCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKEQD 1983
K+E+ C G W C P C+ H TFDG+++ G C Y+L + +D
Sbjct: 398 KIEQECTECVCVGGVWNCTEQDCPVQCSVVGDSHFTTFDGRHYSFIGMCQYILVKGTGKD 457
Query: 1984 -LEVILHNGACSPGARQGCMKSIEVKHSALSVELHSDMEVTVNGRLVSVPYVGGNM---- 2038
+ L C C++SI + L + + + + G++++ P G N+
Sbjct: 458 KFTITLQKAPCEQNLGLVCLQSITL---ILEDDFNKQVTLGRGGQILTSPNQGFNLNGIV 514
Query: 2039 EVNVYGAIMHEVRFNHLGHIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFML 2098
E+ ++ ++ G F +QL+ + +T GLCG + N +DF+
Sbjct: 515 EIQTLSSLFILLKTT-FGLKILFAIDGERIYIQLT-SAWKRRTLGLCGTFNGNIRDDFLS 572
Query: 2099 RDGTVTTDWKTLVQEWTVQRPGQTC---------QPILEEQCLVPDSSHCQVLLLPLFAE 2149
G + + W V TC P Q + ++HC V+ LFA
Sbjct: 573 PSGMIEGTPQLHANAWRVS---STCFAPVHVPVVDPCNINQQNIGYAAHCDVIHQELFAP 629
Query: 2150 CHKVLAPATFYAICQQDSCH--QEQVCEVIASYAHLCRTNGVCVDWRTP-DFCAMSCPPS 2206
CH ++P +Y +C+ D+C +C +A YA+LC +GV +D+RT FCA+ C
Sbjct: 630 CHIYISPGLYYQLCRHDACKCGSSCLCNALAHYAYLCGQHGVPIDFRTQISFCAVVCQKG 689
Query: 2207 LVYNHCEHGCPRHCD--GNVSSCGDHPSEGCFCPPDKVMLE--GSCVPEEACTQCIGEDG 2262
++Y+HC C C + C D +EGC CP K + CVP C +C
Sbjct: 690 MLYHHCSSFCLHSCISLSSPEQCSDDCAEGCNCPEGKFYEDTLNFCVPIFHC-RCHYRGS 748
Query: 2263 VQHQFLEAWVPDHQPCQICTCLSGRKVNCTTQPCPTA 2299
V +P P +C C +G V C P+A
Sbjct: 749 VYQP--GELIP--TPSGLCQCSNG-TVKCDELATPSA 780
Score = 115 bits (289), Expect = 5e-25
Identities = 106/373 (28%), Positives = 149/373 (39%), Gaps = 38/373 (10%)
Query: 1949 VCTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKEQDLE----VILHNGACSPGARQGCMKS 2004
+C H TFDG + G+CSY+ F DLE V +HN G+ C +S
Sbjct: 63 ICKTWGQYHFETFDGIYYYFPGNCSYI-FAKDCGDLEPRYTVWVHNSPKCLGSVYSCYRS 121
Query: 2005 IEVKHSALSVELHSDMEVTVNGRLVSVPYVGGNMEVN-VYGAIMHEVRFNHLGHIFTFTP 2063
I + S E+ NG +++P G + + + I+ + F F+
Sbjct: 122 ISLFFSNQEEIRIYGHEIKKNGISLTLPQTIGQIFIEKLADYILVKTTFG-----FSLAW 176
Query: 2064 QN-NEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTVQRPGQT 2122
+ L+LS + K+ GLCG ++ ++DF++ T D W+VQ P T
Sbjct: 177 DGISGIYLKLS-EDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDT 235
Query: 2123 CQPILEEQCLVPDSS----------HCQVLLLPLFAECHKVLAPATFYAICQQDSC---H 2169
+ P SS CQ+LL F CH+ + P + A C D C
Sbjct: 236 KCVLTPSDFPNPCSSGMPAFEAIFFKCQILLQFPFLSCHEYIDPYLYIASCVNDLCKTDD 295
Query: 2170 QEQVCEVIASYAHLCRTNGVCV-DWRTPDF--CAMSCPPSLVYNHCEHGCPRHCDGNVSS 2226
E C YA C G + DWR DF C C S V+ C CP C
Sbjct: 296 DETYCRAATEYARACSHAGYPIQDWR-DDFPACTDKCDDSFVHRDCISCCPPTCTFEKQC 354
Query: 2227 CGD--HPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWVPDHQPCQICTCL 2284
G H +GC+CP VM G+C+ E C G G+ + Q C C C+
Sbjct: 355 LGSNLHCLDGCYCPDGLVMDNGTCISLENCP--CGFHGLAY---SVGSKIEQECTECVCV 409
Query: 2285 SGRKVNCTTQPCP 2297
G NCT Q CP
Sbjct: 410 GG-VWNCTEQDCP 421
Score = 85.9 bits (211), Expect = 5e-16
Identities = 108/501 (21%), Positives = 173/501 (34%), Gaps = 110/501 (21%)
Query: 301 YRQCVSPCARTCQSLHINEMCQERCVDGCS--CPEGQLLDEGL--CVESTEC-PCVHSGK 355
Y C +PC +TC V+GC CP+ +LDE CV +C P + +
Sbjct: 1281 YEPCATPCFKTCSDPEALACKFLPPVEGCLPYCPKNMILDEVTLKCVYPRDCIPVIPTEP 1340
Query: 356 RY----------------------------PPGTSLS---------RDCNTCICRNSQW- 377
P T L DC+ IC N +W
Sbjct: 1341 TLMPPAKPTVPMFTVWEMITPSDITVFDMLTPTTGLECEPQKFDPVYDCSQYICLNMEWQ 1400
Query: 378 ------------------------------ICSNEECPGECLVTGQSHFKSFDNRYFTFS 407
C ECP C + + +FD
Sbjct: 1401 LYNWSLNCPKDVEMPDCGFRGRPVQVNSDICCPEWECPCRCSMLSELSIITFDGNNAALY 1460
Query: 408 GICQYLLARDCQDHSFSIVIETVQCADDR------DAVCTRSVTVRLPGLHNSLVKLKHG 461
+ Y+L R + IV +C+ ++ +C + + V P +H +V +
Sbjct: 1461 SMASYILVRIPGE---IIVAHIEKCSMNQAPSGRISGLCFKKLNVTTP-IHKIIVN-RLA 1515
Query: 462 AGVAMDGQDVQLPLLKGDLRIQHTVTASVRLSYGEDLQMDWDGRGRLLVKLSPVYAG--- 518
V +D V LP +L I+ + + V ++ L + W L + ++ G
Sbjct: 1516 RKVEVDSIVVPLPFSSQELSIEDSGSMYV-ITTPAGLIIKWSH----LTGIIDIHFGFRF 1570
Query: 519 ----KTCGLCGNYNGNQGDDFLTPSGLAEPRVEDFG---NAWKLHGDCQDLQKQHSDPCA 571
T GLCG N + DD +G +ED G +W++ + ++ C
Sbjct: 1571 NLSSYTEGLCGICNEDPDDDLRMQNGTIITNMEDIGLFIESWEIEKSFEVTMRRPVRNCT 1630
Query: 572 LNPRMTRFSEEACAVLTSPTFEACHRAVSPLPYLRNCRYDVCSCSDGRECLCGALASYAA 631
+ + +L F CH VSP + C + + C AL++Y A
Sbjct: 1631 EHD-----CSQCIDLLNRRIFIPCHDKVSPEDF---CEKMWINYTYFWNYECDALSAYVA 1682
Query: 632 ACAGRGVRVAWREPGRCELNCPKGQVYLQCGTPCNL-TCRSLSYPDEECNEACLEGCFCP 690
C + + WR P C L+CP+G+ Y C PC TC + + E C C
Sbjct: 1683 LCNKFDICIQWRTPDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTSCLNLREDCVCK 1742
Query: 691 PG--LYMDERGDCVPKAQCPC 709
G L+ C+P+ +C C
Sbjct: 1743 VGTILHRPHSAQCIPEKECAC 1763
Score = 84.7 bits (208), Expect = 1e-15
Identities = 63/271 (23%), Positives = 113/271 (41%), Gaps = 17/271 (6%)
Query: 1944 WTCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKEQ-DLEVILHNGACSPGARQGCM 2002
+ CP VCT RH +FDG + C L ++ + D+ VI N C C
Sbjct: 847 YPCPAVCTIYGDRHYYSFDGLEYDYISDCQVFLIKSADDSDISVIAQNKKCFDNDIV-CS 905
Query: 2003 KSIEVKHSALSVELHSDMEVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHLGHIFTFT 2062
KS+ + + L+ T + S ++ ++ A + V + I
Sbjct: 906 KSVLISVGDTEIYLND----TPYKQKQSGFFLENKSTYQLWKAGYYIVVYFPEKDITILW 961
Query: 2063 PQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTV---QRP 2119
+ +++ P+ + +K GLCG D+ +ND + + + W + + P
Sbjct: 962 DRKTTIHIKVGPQ-WKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGDSWALGQCESP 1020
Query: 2120 GQTCQPILEEQCLVPDSS-HCQVLLLPLFAECHKVLAPATFYAICQQDSCHQ------EQ 2172
+T +P Q P + C +L +FA C V+ +F C +D+C+ E
Sbjct: 1021 DETIKPCEAHQNKFPYAKKECSILYSDIFASCRNVIDVTSFAKNCHEDTCNCNLGGDCEC 1080
Query: 2173 VCEVIASYAHLCRTNGVCVDWRTPDFCAMSC 2203
+C IA+YA+ C G+ + WR+ C++ C
Sbjct: 1081 LCTSIAAYAYKCCQEGISIHWRSSTVCSLDC 1111
Score = 82.4 bits (202), Expect = 6e-15
Identities = 90/341 (26%), Positives = 131/341 (38%), Gaps = 35/341 (10%)
Query: 34 RCSLFGSDFVNTFDGS---MYSFAGYCSYLLAGGCQKRSFS--IIGDFQNGKRVSLSVY- 87
RCS+ + TFDG+ +YS A Y + G + +G+ L
Sbjct: 1440 RCSMLSELSIITFDGNNAALYSMASYILVRIPGEIIVAHIEKCSMNQAPSGRISGLCFKK 1499
Query: 88 LGEFFDIHLFVNGTVTQGDQR----VSMPYASKGLYLETEAGYYKLSGEAYGFVARIDGS 143
L IH + + + + V +P++S+ L +E Y ++ A + +
Sbjct: 1500 LNVTTPIHKIIVNRLARKVEVDSIVVPLPFSSQELSIEDSGSMYVITTPAGLIIKWSHLT 1559
Query: 144 GNFQVLLSDRY--FNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYD---FANSWALSSGEQ 198
G + R+ + T GLCG N +DD Q GT+ ++ D F SW + +
Sbjct: 1560 GIIDIHFGFRFNLSSYTEGLCGICNEDPDDDLRMQNGTIITNMEDIGLFIESWEIEKSFE 1619
Query: 199 WCERASPPSSSCNISSGEMQKGLWEQCQLLKSTSVFARCHPLVDPEPFVALCEKTLCECA 258
R P +C QC L + +F CH V PE F CEK
Sbjct: 1620 VTMRR--PVRNCTEHD-------CSQCIDLLNRRIFIPCHDKVSPEDF---CEKMWINYT 1667
Query: 259 GGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPC-ARTC--QSL 315
C AL Y C + + + W CS CP G EY+ CV PC ARTC Q
Sbjct: 1668 YFWNYECDALSAYVALCNKFDICIQ-WRTPDYCSLSCPEGKEYQPCVRPCEARTCLNQWF 1726
Query: 316 HINEMCQERCVDGCSCPEGQLL---DEGLCVESTECPCVHS 353
+ + C D C C G +L C+ EC C S
Sbjct: 1727 YGHTSCLNLRED-CVCKVGTILHRPHSAQCIPEKECACTDS 1766
Score = 66.2 bits (160), Expect = 4e-10
Identities = 30/56 (53%), Positives = 33/56 (58%), Gaps = 1/56 (1%)
Query: 1142 CEWRYNSCAPACQVTCQHPEPLACP-VQCVEGCHAHCPPGKILDELLQTCVDPEDC 1196
CEWRY CA C TC PE LAC + VEGC +CP ILDE+ CV P DC
Sbjct: 1277 CEWRYEPCATPCFKTCSDPEALACKFLPPVEGCLPYCPKNMILDEVTLKCVYPRDC 1332
Score = 55.1 bits (131), Expect = 1e-06
Identities = 89/398 (22%), Positives = 141/398 (35%), Gaps = 87/398 (21%)
Query: 839 GETVKIGCNTCVCRDRKWNCTDHVCDATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYC 898
G V++ + C C + C CS + +TFDG Y+LV+
Sbjct: 1421 GRPVQVNSDIC--------CPEWECPCRCSMLSELSIITFDGNNAALYSMASYILVRI-- 1470
Query: 899 GSNPGTFRILVGNKGCSH---PSVK----CKKRVTILVEGGEI-------ELFDGEVNVK 944
PG I+ + CS PS + C K++ + +I ++ + V
Sbjct: 1471 ---PGEI-IVAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVVP 1526
Query: 945 RPMKDETHFEVVESGRYIILLLGKALSVVW-------DRHLSISVVLKQTYQEKVCGLCG 997
P + + +SG ++ L + W D H L +Y E +CG+C
Sbjct: 1527 LPFSSQ-ELSIEDSGSMYVITTPAGLIIKWSHLTGIIDIHFGFRFNLS-SYTEGLCGIC- 1583
Query: 998 NFDGIQNNDLTSSNLQVEEDPVDFG---NSWKVSSQCADTRKVPLDSSPATCHNNIMKQT 1054
N D ++DL N + + D G SW++ T + P+ + C + Q
Sbjct: 1584 NED--PDDDLRMQNGTIITNMEDIGLFIESWEIEKSFEVTMRRPVRN----CTEHDCSQC 1637
Query: 1055 MVDSSCRILTSDVFQDCNKLVDPEPYLDVCIYDTCSCESIGDCACF-----CDTIAAYAH 1109
+ +L +F C+ V PE + CE + + CD ++AY
Sbjct: 1638 I-----DLLNRRIFIPCHDKVSPEDF----------CEKMWINYTYFWNYECDALSAYVA 1682
Query: 1110 VCAQHGKVVTWRTATLCPQSCEERNLRENGYECEWRYNSCAPACQV-TC------QHPEP 1162
+C + + WRT C SC E Y C C+ TC H
Sbjct: 1683 LCNKFDICIQWRTPDYCSLSCPEGK----------EYQPCVRPCEARTCLNQWFYGHTSC 1732
Query: 1163 LACPVQCV--EGCHAHCP-PGKILDELLQTCVDPEDCP 1197
L CV G H P + + E C D ED P
Sbjct: 1733 LNLREDCVCKVGTILHRPHSAQCIPEKECACTDSEDQP 1770
>gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]
Length = 2639
Score = 569 bits (1466), Expect = e-161
Identities = 393/1278 (30%), Positives = 557/1278 (43%), Gaps = 183/1278 (14%)
Query: 4 ARFAGVLLALALILPGTLCAEGTRGRSSTARCSLFGSDFVNTFDGSMYSFAGYCSYLLAG 63
AR A V LAL+L L EG CS +G+ TFDG ++ F G C Y A
Sbjct: 6 ARLAAVCLALSLAGGSELQTEGRTRNHGHNVCSTWGNFHYKTFDGDVFRFPGLCDYNFAS 65
Query: 64 GCQKRSFSIIGDFQNG----------KRVSLSVYLGEFF-DIHLFV-NGTVTQGDQRVSM 111
C+ + G + + L++ + HL V NG V VS
Sbjct: 66 DCRGSYKEFAVHLKRGPGQAEAPAGVESILLTIKDDTIYLTRHLAVLNGAV------VST 119
Query: 112 PYASKGLYLETEAGYYKLSGEAYGFVARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAED 171
P+ S GL +E Y K+ A G + + L ++ N TCGLCG++N
Sbjct: 120 PHYSPGLLIEKSDAYTKVYSRA-GLTLMWNREDALMLELDTKFRNHTCGLCGDYNGLQSY 178
Query: 172 DFMTQEGTLTSDPYDFANSWALSSGEQWCERASPPSSSCNISSGEMQKGLWEQCQLLKST 231
+G L S P +F N ++ + P C
Sbjct: 179 SEFLSDGVLFS-PLEFGNM----------QKINQPDVVCE-------------------- 207
Query: 232 SVFARCHPLVDPEPFVALCEKTLCECAGGLECACPALLEYARTCAQEGMVLYGWTDHSAC 291
DPE VA PA R + + + D C
Sbjct: 208 ----------DPEEEVA-----------------PASCSEHRAECERLLTAEAFAD---C 237
Query: 292 SPVCPAGMEYRQCVSPCARTCQSLHINEMCQERCVDGCSCPEGQLLDEGLCVESTECP-- 349
+ P + P R CQ D C CP G CV ST
Sbjct: 238 QDLVP--------LEPYLRACQQ------------DRCRCPGGDT-----CVCSTVAEFS 272
Query: 350 --CVHSGKRYPPGTSLSRDCNTCICRNSQWICSNEECPGECLVTGQSHFKSFDNRYFTFS 407
C H+G R PG R + + + ++ CPG LV +S D
Sbjct: 273 RQCSHAGGR--PGNW--RTATSAVSPGA-----SKTCPGN-LVYLESGSPCMDT------ 316
Query: 408 GICQYL-LARDCQDHSFSIVIETVQCADDRDAVCTRSVTVRLPGLHNSLVKLKHGAGVAM 466
C +L ++ C++H ++ C + A ++V V L ++V K V +
Sbjct: 317 --CSHLEVSSLCEEHR----MDGCFCPEGAQADLPKTV-VLLADKKKNVVVFKSDGSVLL 369
Query: 467 DGQDVQLPLLKGDLRI--QHTVTASVRLSYGEDLQMDWDGRGRLLVKLSPVYAGKTCGLC 524
+ V LP + + + V ++ G LQ+ +L V L G+ GLC
Sbjct: 370 NELQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQGLC 429
Query: 525 GNYNGNQGDDFLTPSGLAEPRVEDFGNAWKLHGDCQDLQKQHSDPCALNPRMTRFSEEAC 584
GN+NG +GDDF T SGL E F N WK C D DPC+LN ++E C
Sbjct: 430 GNFNGLEGDDFKTASGLVEATGAGFANTWKAQSSCHDKLDWLDDPCSLNIESANYAEHWC 489
Query: 585 AVL--TSPTFEACHRAVSPLPYLRNCRYDVCSCSDGRECLCGALASYAAACAGRGVRV-A 641
++L T F CH AV P Y + C+YD C+C + +CLC AL+SYA AC +GV +
Sbjct: 490 SLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACTAKGVMLWG 549
Query: 642 WREP--GRCELNCPKGQVYLQCGTPCNLTCRSLSYPDEECNE--ACLEGCFCPPGLYMDE 697
WRE + +CP QV+L T C TCRSLS D C E A ++GC CP ++DE
Sbjct: 550 WREHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFAPVDGCGCPDHTFLDE 609
Query: 698 RGDCVPKAQCPCYYDGEIFQPEDIFSDHHTMCYCEDGFMHCTMSGVPGSLLPDAVLSSPL 757
+G CVP A+C CY+ G + D+ C C DG +HC + G
Sbjct: 610 KGRCVPLAKCSCYHRGLYLEAGDVVVRQEERCVCRDGRLHCRQIRLIGQ----------- 658
Query: 758 SHRSKRSLSCRPPMVKLVCPADNLRAEGLECTKTCQNYDLECMSMGCVSGCLCPPGMVRH 817
SC P + + C A +CQ CVSGC+CP G++
Sbjct: 659 --------SCTAPKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPDGLMDD 710
Query: 818 -ENRCVALERCPCFHQGKEYAPGETVKIGCNTCVCRDRKWNCTDHVCDATCSTIGMAHYL 876
CV + CPC H Y+ G +K+ CNTC C+ +W CT VC TCS G HY+
Sbjct: 711 GRGGCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAVCHGTCSIYGSGHYI 770
Query: 877 TFDGLKYLFPGECQYVLVQDYCGSNP--GTFRILVGNKGCSHPSVKCKKRVTILVEGGEI 934
TFDG Y F G C YV VQDYCG N G+F I+ N C V C K + I + E+
Sbjct: 771 TFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGVTCSKAIKIFMGRTEL 830
Query: 935 ELFD-GEVNVKRPMKDETHFEVVESGRYIILLLGKALSVVWDRHLSISVVLKQTYQEKVC 993
+L D V ++R + E G+Y+++ + V+WD+ ++ + L +Y+ VC
Sbjct: 831 KLEDKHRVVIQRDEGHHVAYTTREVGQYLVVESSTGIIVIWDKRTTVFIKLAPSYKGTVC 890
Query: 994 GLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKVSSQCADTRKVPLDSSPATCHNNIMKQ 1053
GLCGNFD NND T+ + V +DFGNSWK + C D + ++P C N ++
Sbjct: 891 GLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEAPTCPD-----VSTNPEPCSLNPHRR 945
Query: 1054 TMVDSSCRILTSDVFQDCNKLVDPEPYLDVCIYDTCSCESIGDCACFCDTIAAYAHVCAQ 1113
+ + C IL S VF C+ VDP+P+ + C++D+CSC++ GDC CFC +A+YA C +
Sbjct: 946 SWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTK 1005
Query: 1114 HGKVVTWRTATLCPQSCEERNLRENGYECEWRYNSCAPACQVTCQHPEPL--ACPVQCVE 1171
G V WRT LCP C+ N +ECEW Y C TC+ + V +E
Sbjct: 1006 EGACVFWRTPDLCPIFCDYYN---PPHECEWHYEPCGNRSFETCRTINGIHSNISVSYLE 1062
Query: 1172 GCHAHCPPGK-ILDELLQTCVDPEDCPVCEVAGRRFASGKKVTLNPSDPEHCQICHCDVV 1230
GC+ CP + I +E L+ CV + C C V + G V P++ E C+ C C
Sbjct: 1063 GCYPRCPKDRPIYEEDLKKCVTADKCG-CYVEDTHYPPGASV---PTE-ETCKSCVC--T 1115
Query: 1231 NLTCEACQEPGGLVVPPT 1248
N + C+ G ++ T
Sbjct: 1116 NSSQVVCRPEEGKILNQT 1133
Score = 252 bits (643), Expect = 4e-66
Identities = 213/807 (26%), Positives = 315/807 (39%), Gaps = 138/807 (17%)
Query: 1879 CMDEDGNEKRPGDVWTLPDQCHTVTCQPDGQTLLKSHRVNCDRGLRPSCPNSQSPVKVEE 1938
C D D ++ + W L D C TC+ + + +V C+ P+C N PV+VE+
Sbjct: 1872 CPDFDP-PRQENETWWLCD-CFMATCKYNNTVEIV--KVECEPPPMPTCSNGLQPVRVED 1927
Query: 1939 TCGC--RWTCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKEQDLE---VILHNGAC 1993
GC W C C CTG H VTFDG + G+C+YVL + ++ V + N C
Sbjct: 1928 PDGCCWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHC 1987
Query: 1994 SPGARQGCMKSIEVKHSALSVELHS------DMEVTVNGRLVSVPYVGGNMEVNVYGAIM 2047
P + C +++ V+H V + + ++V VN + V++PY +EV G I
Sbjct: 1988 DPNDKVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSG-IN 2046
Query: 2048 HEVRFNHLGHIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDW 2107
+ V LG + ++ F ++L F + T G CG C ++D +L G + ++
Sbjct: 2047 YVVDIPELGVLVSY--NGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNC 2104
Query: 2108 KTLVQEWTVQRPGQTCQPILEEQCLVP-----------------DSSHCQVLLLPLFAEC 2150
+ +W V P + P P S CQ++ LFA+C
Sbjct: 2105 EAAADQWLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQC 2164
Query: 2151 HKVLAPATFYAICQQDSCH---QEQVCEVIASYAHLCRTNGVCVDWR--TPDFCAMSCPP 2205
H ++ P +Y C DSC C + +YA LC +C+DWR T C + CP
Sbjct: 2165 HALVPPQHYYDACVFDSCFMPGSSLECASLQAYAALCAQQNICLDWRNHTHGACLVECPS 2224
Query: 2206 SLVYNHCEHGCPRHCDGNVSSCGDHP-SEGCFCPPDKV-MLEGSCVPEEACTQCIGEDGV 2263
Y C C + S + EGCFCP + G V + C C+G D V
Sbjct: 2225 HREYQACGPAEEPTCKSSSSQQNNTVLVEGCFCPEGTMNYAPGFDVCVKTC-GCVGPDNV 2283
Query: 2264 QHQFLEAWVPDHQPCQICTCLSGRKVNCTTQPCPTAKAPTCGLCEVARLRQNADQCCPEY 2323
+F E + D C+ C CL G
Sbjct: 2284 PREFGEHFEFD---CKNCVCLEGGS----------------------------------- 2305
Query: 2324 ECVCDPVSCDLPPVPHC-ERGLQ-PTLTNPGECRPNFT-CACRKEECKRVSPPSCPPHRL 2380
+C P C PV HC E G T NP + N T C C CK PS
Sbjct: 2306 GIICQPKRCSQKPVTHCVEDGTYLATEVNPADTCCNITVCKCNTSLCK--EKPSV----- 2358
Query: 2381 PTLRKTQCCDEYECACNCVNSTVSCPLGY-LASTATNDCGCTTTTCLPDKVCVHRSTIY- 2438
CPLG+ + S C C VCVH + Y
Sbjct: 2359 ------------------------CPLGFEVKSKMVPGRCCPFYWCESKGVCVHGNAEYQ 2394
Query: 2439 PVGQFWEEGCDVCTCTDMEDAVMGLRVAQCSQKPCEDSCRSGFTYVLHEGECCGRCLPSA 2498
P + C C CTD D L V C+ PC SC GF + GECC +C +
Sbjct: 2395 PGSPVYSSKCQDCVCTDKVDNNTLLNVIACTHVPCNTSCSPGFELMEAPGECCKKCEQTH 2454
Query: 2499 CEVVTGSPRGDSQSSWKSVGSQWASPENPCLINECVRVKEEVFIQQRNVSCPQLEVPVCP 2558
C + R D+Q G + P+N C CV++ ++ N++CP + +C
Sbjct: 2455 CII----KRPDNQHVILKPGDFKSDPKNNCTFFSCVKIHNQLISSVSNITCPNFDASICI 2510
Query: 2559 SGFQLSCKTSACCPSC--RCERMEAC-----MLNGTVIGPGKTVMIDVCT-TCRCMVQVG 2610
G ++ + CC +C R E C + G KTV+++ C+ +C V
Sbjct: 2511 PG-SITFMPNGCCKTCTPRNETRVPCSTVPVTTEVSYAGCTKTVLMNHCSGSCGTFVMYS 2569
Query: 2611 VISGFKLECRKTTCNPCPLGYKEENNT 2637
K + +C+ C KEE +
Sbjct: 2570 A----KAQALDHSCSCC----KEEKTS 2588
Score = 131 bits (329), Expect = 1e-29
Identities = 147/591 (24%), Positives = 215/591 (36%), Gaps = 96/591 (16%)
Query: 358 PPGTSLSRDCNTCICRNSQWICSNEECPGECLVTGQSHFKSFDNRYFTFSGICQYLLARD 417
PP + S + C + EC C G H+ +FD Y+++ G C Y+L +
Sbjct: 1911 PPMPTCSNGLQPVRVEDPDGCCWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEE 1970
Query: 418 CQD--HSFSIVIETVQCADDRDAVCTRSVTVRLPGLHNSLVKLKH----GAGVAMDGQDV 471
+F + I+ C + C R++ VR L+K H V ++ Q V
Sbjct: 1971 ISPSVDNFGVYIDNYHCDPNDKVSCPRTLIVR-HETQEVLIKTVHMMPMQVQVQVNRQAV 2029
Query: 472 QLPLLKGDLRIQHTVTASVRLSYGEDLQ-----MDWDGRGRLLVKLSPVYAGKTCGLCGN 526
LP K L + + ++Y D+ + ++G + + T G CG
Sbjct: 2030 ALPYKKYGLEVYQS-----GINYVVDIPELGVLVSYNGLSFSVRLPYHRFGNNTKGQCGT 2084
Query: 527 YNGNQGDDFLTPSGLAEPRVEDFGNAWKLHGDCQDLQKQHSDPCALNPRMT--------- 577
DD + PSG E + W L D HS P +T
Sbjct: 2085 CTNTTSDDCILPSGEIVSNCEAAADQW-LVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTP 2143
Query: 578 ---RFSEEACAVLTSPTFEACHRAVSPLPYLRNCRYDVCSCSDGRECLCGALASYAAACA 634
C ++ F CH V P Y C +D C G C +L +YAA CA
Sbjct: 2144 HKDCTPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSC-FMPGSSLECASLQAYAALCA 2202
Query: 635 GRGVRVAWRE--PGRCELNCPKGQVYLQCGTPCNLTCRSLSYPDEECNEACLEGCFCPPG 692
+ + + WR G C + CP + Y CG TC+S S ++ N +EGCFCP G
Sbjct: 2203 QQNICLDWRNHTHGACLVECPSHREYQACGPAEEPTCKSSS--SQQNNTVLVEGCFCPEG 2260
Query: 693 LYMDERGDCVPKAQCPCYYDGEIFQPEDIFSDHHTM----CYCEDGFMHCTMSGVPGSLL 748
G V C C + P + F +H C C +G SG+
Sbjct: 2261 TMNYAPGFDVCVKTCGCVGPDNV--PRE-FGEHFEFDCKNCVCLEG-----GSGI--ICQ 2310
Query: 749 PDAVLSSPLSHRSKRSLSCRPPMVKLVCPADNLRAEGLECTKTCQNYDL-ECMSMGC-VS 806
P P++H + + V PAD TC N + +C + C
Sbjct: 2311 PKRCSQKPVTH----CVEDGTYLATEVNPAD-----------TCCNITVCKCNTSLCKEK 2355
Query: 807 GCLCPPGMVRHENRCVALERCP---------CFHQGKEYAPGETV-KIGCNTCVCRDRKW 856
+CP G +++ V CP C H EY PG V C CVC D+
Sbjct: 2356 PSVCPLGF-EVKSKMVPGRCCPFYWCESKGVCVHGNAEYQPGSPVYSSKCQDCVCTDKVD 2414
Query: 857 N--------CTDHVCDATCSTIGMAHYLTFDGLKYL-FPGECQYVLVQDYC 898
N CT C+ +CS G + + PGEC Q +C
Sbjct: 2415 NNTLLNVIACTHVPCNTSCS----------PGFELMEAPGECCKKCEQTHC 2455
Score = 122 bits (306), Expect = 5e-27
Identities = 127/453 (28%), Positives = 179/453 (39%), Gaps = 85/453 (18%)
Query: 1898 QCHTVTCQPDGQTLLKSHRVNCDRGLRPSCP--------NSQSPVKVE-ETCGC---RWT 1945
+C + PDG L+ R C + CP +S + +KV+ TC C RW
Sbjct: 696 ECVSGCVCPDG--LMDDGRGGCV--VEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWV 751
Query: 1946 CP-CVCTGS----STRHIVTFDGQNFKLTGSCSYVLFQN------KEQDLEVILHNGACS 1994
C VC G+ + H +TFDG+ + G CSYV Q+ +I N C
Sbjct: 752 CTQAVCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCG 811
Query: 1995 PGARQGCMKSIEVKHSALSVELHSDMEVTVN---GRLVSVPYVGGNMEVNVYGAIMHEVR 2051
C K+I++ ++L V + G V+ EV Y +
Sbjct: 812 TTGVT-CSKAIKIFMGRTELKLEDKHRVVIQRDEGHHVAYT----TREVGQYLVVESST- 865
Query: 2052 FNHLGHIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLV 2111
G I + + F ++L+P ++ GLCG D NDF RD V +
Sbjct: 866 ----GIIVIWDKRTTVF-IKLAP-SYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFG 919
Query: 2112 QEWTVQRPGQTCQPILE--EQCLVPD------SSHCQVLLLPLFAECHKVLAPATFYAIC 2163
W + TC + E C + C +L +F+ CH + P FY C
Sbjct: 920 NSW---KEAPTCPDVSTNPEPCSLNPHRRSWAEKQCSILKSSVFSICHSKVDPKPFYEAC 976
Query: 2164 QQDSCHQ------EQVCEVIASYAHLCRTNGVCVDWRTPDFCAMSCPPSLVYNHCEHGCP 2217
DSC E C +ASYA C G CV WRTPD C + C Y + H C
Sbjct: 977 VHDSCSCDTGGDCECFCSAVASYAQECTKEGACVFWRTPDLCPIFCD----YYNPPHECE 1032
Query: 2218 RHCD--GNVS--SC----GDHPS------EGCF--CPPDKVMLE---GSCVPEEACTQCI 2258
H + GN S +C G H + EGC+ CP D+ + E CV + C C
Sbjct: 1033 WHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKC-GCY 1091
Query: 2259 GEDGVQHQFLEAWVPDHQPCQICTCLSGRKVNC 2291
ED H A VP + C+ C C + +V C
Sbjct: 1092 VED--THYPPGASVPTEETCKSCVCTNSSQVVC 1122
Score = 120 bits (301), Expect = 2e-26
Identities = 108/452 (23%), Positives = 157/452 (34%), Gaps = 76/452 (16%)
Query: 2374 SCPPHRLPTLRKTQCCDEYEC---ACNCVNSTVSCPLGYLASTATNDCGCTTTTCLPDKV 2430
+C P PT + + C C T++ G+ T CGC +P +
Sbjct: 2230 ACGPAEEPTCKSSSSQQNNTVLVEGCFCPEGTMNYAPGFDVCVKT--CGCVGPDNVPREF 2287
Query: 2431 CVHRSTIYPVGQFWEEGCDVCTCTDMEDAVMGLRVAQCSQKPCEDSCRSGFTYVLHEGEC 2490
G+ +E C C C + ++ + +CSQKP G TY+ E
Sbjct: 2288 ----------GEHFEFDCKNCVCLEGGSGII-CQPKRCSQKPVTHCVEDG-TYLATEVNP 2335
Query: 2491 CGRCLPSACEVVTGSPRGDSQSSWKSVGSQWASPENPCLINECVRVKEEVFIQQRNVSCP 2550
C C I C + N S
Sbjct: 2336 ADTC---------------------------------CNITVC----------KCNTSLC 2352
Query: 2551 QLEVPVCPSGFQLSCKT--SACCPSCRCERMEACMLNGTVIGPGKTVMIDVCTTCRCMVQ 2608
+ + VCP GF++ K CCP CE C+ PG V C C C +
Sbjct: 2353 KEKPSVCPLGFEVKSKMVPGRCCPFYWCESKGVCVHGNAEYQPGSPVYSSKCQDCVCTDK 2412
Query: 2609 VGVISGFK-LECRKTTCNP-CPLGYKEENNTGECCGRCLPTACTIQLRGGQIMTLKRDET 2666
V + + C CN C G++ GECC +C T C I+ Q + LK +
Sbjct: 2413 VDNNTLLNVIACTHVPCNTSCSPGFELMEAPGECCKKCEQTHCIIKRPDNQHVILKPGDF 2472
Query: 2667 LQDGCD--THFCKVNERGEYFWEKRVTGCPPFDEHKCLAEGGKIMKIPGTCCDTCEEPE- 2723
D + T F V + CP FD C+ G I +P CC TC
Sbjct: 2473 KSDPKNNCTFFSCVKIHNQLISSVSNITCPNFDASICIP--GSITFMPNGCCKTCTPRNE 2530
Query: 2724 ----CNDITARLQYVKVGSCKSEVEVDIHYCQGKCASKAMYSIDINDVQDQCSCCSPTRT 2779
C+ + + G K+ V +++C G C + MYS + CSCC +T
Sbjct: 2531 TRVPCSTVPVTTEVSYAGCTKT---VLMNHCSGSCGTFVMYSAKAQALDHSCSCCKEEKT 2587
Query: 2780 EPMQVALHCTNGSVVYHEVLNAMECKCSPRKC 2811
+V L C NG + H + C+C C
Sbjct: 2588 SQREVVLSCPNGGSLTHTYTHIESCQCQDTVC 2619
Score = 109 bits (273), Expect = 3e-23
Identities = 120/478 (25%), Positives = 181/478 (37%), Gaps = 83/478 (17%)
Query: 827 CPCFHQGKEYAPG-ETVKIGCN-----TCV-------CRDRKWNCTDHVCDATCSTIGMA 873
C CF +Y E VK+ C TC D C CD C+ G
Sbjct: 1888 CDCFMATCKYNNTVEIVKVECEPPPMPTCSNGLQPVRVEDPDGCCWHWECDCYCTGWGDP 1947
Query: 874 HYLTFDGLKYLFPGECQYVLVQDYCGSNPGTFRILVGNKGCS-HPSVKCKKRVTILVEGG 932
HY+TFDGL Y + G C YVLV++ S F + + N C + V C + + + E
Sbjct: 1948 HYVTFDGLYYSYQGNCTYVLVEEISPS-VDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQ 2006
Query: 933 EIEL-------FDGEVNVKR-----PMKDETHFEVVESGRYIILLLGKALSVVWDRHLSI 980
E+ + +V V R P K + EV +SG ++ + + +V LS
Sbjct: 2007 EVLIKTVHMMPMQVQVQVNRQAVALPYK-KYGLEVYQSGINYVVDIPELGVLVSYNGLSF 2065
Query: 981 SVVLK-QTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKVSS-------QCA 1032
SV L + G CG ++D + ++ + + W V+ +
Sbjct: 2066 SVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCPHSS 2125
Query: 1033 DTRKVPLDSSPATCHNNIMKQTMVDSSCRILTSDVFQDCNKLVDPEPYLDVCIYDTCSCE 1092
T K P + P K C+++ +F C+ LV P+ Y D C++D+C
Sbjct: 2126 STTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSC--- 2182
Query: 1093 SIGDCACFCDTIAAYAHVCAQHGKVVTWRTAT--LCPQSCEERNLRENGYECEWRYNSCA 1150
+ + C ++ AYA +CAQ + WR T C C Y +C
Sbjct: 2183 FMPGSSLECASLQAYAALCAQQNICLDWRNHTHGACLVECPSHR----------EYQACG 2232
Query: 1151 PACQVTCQHPEPLACPVQCVEGCHAHCPPGKI-----LDELLQT--CVDPEDCPVCEVAG 1203
PA + TC+ VEGC CP G + D ++T CV P++ P
Sbjct: 2233 PAEEPTCKSSSSQQNNTVLVEGC--FCPEGTMNYAPGFDVCVKTCGCVGPDNVP------ 2284
Query: 1204 RRFASGKKVTLNPSDPEHCQICHCDVVNLTCEACQEPGGLVVPPTDAPVSPTTLYVED 1261
R F EH + D N C + G++ P P T VED
Sbjct: 2285 REFG------------EHFEF---DCKNCVC--LEGGSGIICQPKRCSQKPVTHCVED 2325
Score = 100 bits (249), Expect = 2e-20
Identities = 105/381 (27%), Positives = 156/381 (40%), Gaps = 38/381 (9%)
Query: 35 CSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKR--SFSIIGDFQN---GKRVSLSVYLG 89
C+ +G TFDG YS+ G C+Y+L +F + D + +VS L
Sbjct: 1941 CTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSCPRTLI 2000
Query: 90 EFFD--------IHLF-VNGTVTQGDQRVSMPYASKGLYLETEAGYYKLSGEAYGFVARI 140
+ +H+ + V Q V++PY GL + Y + G +
Sbjct: 2001 VRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELGVLVSY 2060
Query: 141 DGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSS-GEQW 199
+G L R+ N T G CG DD + G + S+ A+ W ++ +
Sbjct: 2061 NGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPH 2120
Query: 200 CERASPPSSSCNISSGEMQKGLWEQ-------CQLLKSTSVFARCHPLVDPEPFVALCEK 252
C +S + ++ K + CQL+K S+FA+CH LV P+ + C
Sbjct: 2121 CPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKD-SLFAQCHALVPPQHYYDACVF 2179
Query: 253 TLCECAG-GLECACPALLEYARTCAQEGMVLYGWTDHS--ACSPVCPAGMEYRQCVSPCA 309
C G LECA +L YA CAQ+ + L W +H+ AC CP+ EY+ C
Sbjct: 2180 DSCFMPGSSLECA--SLQAYAALCAQQNICL-DWRNHTHGACLVECPSHREYQACGPAEE 2236
Query: 310 RTCQSLHINEMCQERCVDGCSCPEGQL-LDEGLCVESTECPCVHSGKRYPP---GTSLSR 365
TC+S ++ V+GC CPEG + G V C CV G P G
Sbjct: 2237 PTCKS-SSSQQNNTVLVEGCFCPEGTMNYAPGFDVCVKTCGCV--GPDNVPREFGEHFEF 2293
Query: 366 DCNTCIC--RNSQWICSNEEC 384
DC C+C S IC + C
Sbjct: 2294 DCKNCVCLEGGSGIICQPKRC 2314
Score = 77.4 bits (189), Expect = 2e-13
Identities = 82/312 (26%), Positives = 125/312 (40%), Gaps = 32/312 (10%)
Query: 1949 VCTGSSTRHIVTFDGQNFKLTGSCSYVL---FQNKEQDLEVILHNGACSPGARQGCMK-S 2004
VC+ H TFDG F+ G C Y + ++ V L G A G
Sbjct: 36 VCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGPGQAEAPAGVESIL 95
Query: 2005 IEVKHSALSVELHSDMEVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHLGHIFTFTPQ 2064
+ +K + + H +NG +VS P+ + + A + ++ G + +
Sbjct: 96 LTIKDDTIYLTRHL---AVLNGAVVSTPHYSPGLLIEKSDA--YTKVYSRAGLTLMWN-R 149
Query: 2065 NNEFQLQLSPKTFASKTYGLCGICDENGANDF--MLRDGTVTTDWKTLVQEWTVQRPGQT 2122
+ L+L K F + T GLCG D NG + L DG + + + + +P
Sbjct: 150 EDALMLELDTK-FRNHTCGLCG--DYNGLQSYSEFLSDGVLFSPLE-FGNMQKINQPDVV 205
Query: 2123 CQPILEEQCLVPDSSH---CQVLL-LPLFAECHKVLAPATFYAICQQDSCH----QEQVC 2174
C+ EE S H C+ LL FA+C ++ + CQQD C VC
Sbjct: 206 CEDPEEEVAPASCSEHRAECERLLTAEAFADCQDLVPLEPYLRACQQDRCRCPGGDTCVC 265
Query: 2175 EVIASYAHLC-RTNGVCVDWRTPDF-----CAMSCPPSLVYNHCEHGCPRHCDG-NVSS- 2226
+A ++ C G +WRT + +CP +LVY C C VSS
Sbjct: 266 STVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCMDTCSHLEVSSL 325
Query: 2227 CGDHPSEGCFCP 2238
C +H +GCFCP
Sbjct: 326 CEEHRMDGCFCP 337
Score = 67.8 bits (164), Expect = 1e-10
Identities = 85/346 (24%), Positives = 129/346 (37%), Gaps = 55/346 (15%)
Query: 1993 CSPGARQGCMKSIEVKHSALS--VELHSDMEVTVNGRLVSVPYVGGNMEVNVYGAIMHEV 2050
C GA+ K++ + V SD V +N V++P+V + V +
Sbjct: 336 CPEGAQADLPKTVVLLADKKKNVVVFKSDGSVLLNELQVNLPHVTASFSVFRPSSY---- 391
Query: 2051 RFNHLGHIFTFTPQNNEFQLQLSP---------KTFASKTYGLCGICDENGANDFMLRDG 2101
HI Q+QL+P + + GLCG + +DF G
Sbjct: 392 ------HIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASG 445
Query: 2102 TVTTDWKTLVQEWTVQRPGQTCQPILEEQCLVPDSS-----HCQVLLLPL---FAECHKV 2153
V W Q L++ C + S H LL F CH
Sbjct: 446 LVEATGAGFANTWKAQSSCHDKLDWLDDPCSLNIESANYAEHWCSLLKKTETPFGRCHSA 505
Query: 2154 LAPATFYAICQQDSC----HQEQVCEVIASYAHLCRTNGVCV-DWRTPDFC---AMSCPP 2205
+ PA +Y C+ D+C +++ +C ++SYA C GV + WR C SCP
Sbjct: 506 VDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACTAKGVMLWGWR-EHVCNKDVGSCPN 564
Query: 2206 SLVYNHCEHGCPRHCDGNVSSCGDH------PSEGCFCPPDKVMLE-GSCVPEEACTQCI 2258
S V+ + C + C ++S H P +GC CP + E G CVP C+ C
Sbjct: 565 SQVFLYNLTTCQQTC-RSLSEADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAKCS-CY 622
Query: 2259 GEDGVQHQFLEAWVPDHQPCQICTCLSG----RKVNCTTQPCPTAK 2300
+ +LEA + + C C G R++ Q C K
Sbjct: 623 H----RGLYLEAGDVVVRQEERCVCRDGRLHCRQIRLIGQSCTAPK 664
>gi|151301154 mucin 6, gastric [Homo sapiens]
Length = 2439
Score = 557 bits (1436), Expect = e-158
Identities = 356/1208 (29%), Positives = 549/1208 (45%), Gaps = 107/1208 (8%)
Query: 34 RCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRSFSIIGDFQNGKRVSLSVYLGEFFD 93
+CS +G+ +TFD +Y F+G C+Y+ A C+ + + G S+S + E
Sbjct: 44 QCSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPTFSVQLRRGPDGSISRIIVELGA 103
Query: 94 IHLFVNGTVTQGDQR--VSMPYASKGLYLETEAGYYKLSGEAYGFVARI--DGSGNFQVL 149
+ V+ + +S+PY S GL + +L + + + VL
Sbjct: 104 SVVTVSEAIISVKDIGVISLPYTSNGLQITPFGQSVRLVAKQLELELEVVWGPDSHLMVL 163
Query: 150 LSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGEQWCERASPPSSS 209
+ +Y + CGLCGNF+ ++F+++EG +P+ FA L + C PS+
Sbjct: 164 VERKYMGQMCGLCGNFDGKVTNEFVSEEGKFL-EPHKFAALQKLDDPGEICTFQDIPSTH 222
Query: 210 CNISSGEMQKGLWEQC-QLLKSTSVFARCHPLVDPEPFVALCEKTLCECA--GGLECACP 266
Q C QLL T V C V EPFV C+ + G +C
Sbjct: 223 VR------QAQHARICTQLL--TLVAPECS--VSKEPFVLSCQADVAAAPQPGPQNSSCA 272
Query: 267 ALLEYARTCAQEGMVLYGWTDHSACSP-VCPAGMEYRQCVSPCARTCQSLHINEMCQERC 325
L EY+R C+ G + W CS CPA Y++C S C +TC + C C
Sbjct: 273 TLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSACVKTCSNPQ--HSCSSSC 330
Query: 326 VDGCSCPEGQLLDE----GLCVESTECPCVHSGKRYPPGTSLSRDCNTCICRNSQWICSN 381
GC CPEG +L++ CV T+CPCV G Y PG C TC C +W+C+
Sbjct: 331 TFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVTIAACQTCRCTLGRWVCTE 390
Query: 382 EECPGECLVTGQSHFKSFDNRYFTFSGICQYLLARDCQ---DHSFSIVIETVQCADDRDA 438
CPG C + G S +FD R + F G C Y+L + Q D + V + +
Sbjct: 391 RPCPGHCSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDGALMAVYDKSGVSHSE-- 448
Query: 439 VCTRSVTVRLPGLHNSLVKLKHGAGVAMDGQDVQLPLLKGDLRIQHTVTASVRL--SYGE 496
T V V + +V + V +G+ LP ++ + + +++ S+G
Sbjct: 449 --TSLVAVVYLSRQDKIV-ISQDEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMATSFGL 505
Query: 497 DLQMDWDGRGRLLVKLSPVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWKLH 556
+L + + V + P + G+T GLCGN+NG+ DDF T G+AE F ++W+
Sbjct: 506 ELVVQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTASLFVDSWRA- 564
Query: 557 GDCQDLQKQHSDPCALNPRMTRFSEEACAVL--TSPTFEACHRAVSPLPYLRNCRYDVCS 614
G+C ++ +DPC+++ +E C++L T FE CH V+P P+ + C Y C+
Sbjct: 565 GNCPAALERETDPCSMSQLNKVCAETHCSMLLRTGTVFERCHATVNPAPFYKRCVYQACN 624
Query: 615 CSDGRECLCGALASYAAACAGRGVRV-AWREP-GRCELNCPKGQVYLQCGTPCNLTCRSL 672
+ +C AL Y AC+ RGV + WR C + C + C TC SL
Sbjct: 625 YEETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFSYNSQACERTCLSL 684
Query: 673 SYPDEECNEACL--EGCFCPPGLYMDERGDCVPKAQCPCYYDGEIFQPEDIFSDHHTM-- 728
S EC+ + + +GC CP G Y++++G+CV KAQCPC +G F I ++ T+
Sbjct: 685 SDRATECHHSAVPVDGCNCPDGTYLNQKGECVRKAQCPCILEGYKF----ILAEQSTVIN 740
Query: 729 ---CYCEDGFMHCTMSGVPGSLLPDAVLSSPLSHRSKRSLSCRPPMVKLVCPADNLRAEG 785
C+C +G + C P L+S C+ P C + G
Sbjct: 741 GITCHCINGRLSCPQR-------PQMFLAS-----------CQAPKTFKSCSQSSENKFG 782
Query: 786 LECTKTCQNY--DLECMSMGCVSGCLCPPGMVRH-ENRCVALERCPCFHQGKEYAPGETV 842
C TCQ + C+ C GC+C G+ + + +CV E CPC G Y G +
Sbjct: 783 AACAPTCQMLATGVACVPTKCEPGCVCAEGLYENADGQCVPPEECPCEFSGVSYPGGAEL 842
Query: 843 KIGCNTCVCRDRKWNCTDHV-CDATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSN 901
C TC C +W C C +TC+ G H +TFDG +++F G C+Y+L D CG N
Sbjct: 843 HTDCRTCSCSRGRWACQQGTHCPSTCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVN 902
Query: 902 PG--TFRILVGNKGCSHPSVKCKKRVTILVEGGEIELFDGEVNVKRPMKDETHFEVVESG 959
TF+IL N C + V C + + I + G + L D V +E H ++ +
Sbjct: 903 DSQPTFKILTENVICGNSGVTCSRAIKIFLGGLSVVLADRNYTVTG---EEPHVQLGVTP 959
Query: 960 RYIILLLGKA------LSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQ 1013
+ L++ + L+++W+RH++I + + + Q+ +CGLCGNF+G +D + +
Sbjct: 960 GALSLVVDISIPGRYNLTLIWNRHMTILIRIARASQDPLCGLCGNFNGNMKDDFETRSRY 1019
Query: 1014 VEEDPVDFGNSWKVSSQCADTRKVPLDSSPATCHNNIMKQTMVDSSCRILTSDVFQDCNK 1073
V ++ NSWK S C D V + P C N +++ + C ++ S F C+
Sbjct: 1020 VASSELELVNSWKESPLCGDVSFV---TDP--CSLNAFRRSWAERKCSVINSQTFATCHS 1074
Query: 1074 LVDPEPYLDVCIYDTCSCESIGDCACFCDTIAAYAHVCAQHGKVVTWRTATLCPQSCEER 1133
V PY + C+ D C C+S GDC C CD +AAYA C G V WRT CP C
Sbjct: 1075 KVYHLPYYEACVRDACGCDSGGDCECLCDAVAAYAQACLDKGVCVDWRTPAFCPIYCGFY 1134
Query: 1134 NLR-ENGY---------ECEWRYNSCAPACQVTCQHPEPLACPVQCVEGCHAHCPPGKIL 1183
N ++G+ C W Y C Q P + P +EGC+ +C +
Sbjct: 1135 NTHTQDGHGEYQYTQEANCTWHYQPCLCPSQ-------PQSVPGSNIEGCY-NCSQDEYF 1186
Query: 1184 DELLQTCV 1191
D CV
Sbjct: 1187 DHEEGVCV 1194
Score = 151 bits (381), Expect = 1e-35
Identities = 111/379 (29%), Positives = 168/379 (44%), Gaps = 45/379 (11%)
Query: 386 GECLVTGQSHFKSFDNRYFTFSGICQYLLARDCQDHSFSIVIETVQCADDRDAVCTRSVT 445
G+C G HF +FD+ + FSG C Y+ A C+D + +VQ D +R +
Sbjct: 43 GQCSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKD---AFPTFSVQLRRGPDGSISRIIV 99
Query: 446 VRLPGLHNSLVKLKHGAGVAMDGQDVQLPLLKGDLRIQHTVTASVRLSYGE---DLQMDW 502
L S+V + D + LP L+I SVRL + +L++ W
Sbjct: 100 ----ELGASVVTVSEAIISVKDIGVISLPYTSNGLQIT-PFGQSVRLVAKQLELELEVVW 154
Query: 503 DGRGRLLVKLSPVYAGKTCGLCGNYNGNQGDDFLTPSG-LAEP-------RVEDFGNAWK 554
L+V + Y G+ CGLCGN++G ++F++ G EP +++D G
Sbjct: 155 GPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFLEPHKFAALQKLDDPGEICT 214
Query: 555 LHGDCQDLQKQHSDPCALNPRMTRFSEEACAVLTSPTFEACHRAVSPLPYLRNCRYDVCS 614
QD+ H R ++ A T A +VS P++ +C+ DV +
Sbjct: 215 F----QDIPSTH----------VRQAQHARICTQLLTLVAPECSVSKEPFVLSCQADVAA 260
Query: 615 CSD--GRECLCGALASYAAACA--GRGVRVAWREPGRCEL-NCPKGQVYLQCGTPCNLTC 669
+ C L+ Y+ C+ G+ VR WR PG C + CP QVY +CG+ C TC
Sbjct: 261 APQPGPQNSSCATLSEYSRQCSMVGQPVR-RWRSPGLCSVGQCPANQVYQECGSACVKTC 319
Query: 670 RSLSYPDEECNEACLEGCFCPPGLYMDERGD---CVPKAQCPCYYDGEIFQPEDIFSDHH 726
S P C+ +C GCFCP G +++ + CVP QCPC G ++ P ++
Sbjct: 320 ---SNPQHSCSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVTIAAC 376
Query: 727 TMCYCEDGFMHCTMSGVPG 745
C C G CT PG
Sbjct: 377 QTCRCTLGRWVCTERPCPG 395
Score = 142 bits (357), Expect = 6e-33
Identities = 105/366 (28%), Positives = 153/366 (41%), Gaps = 18/366 (4%)
Query: 29 RSSTARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRSFSIIGDFQNGKRVSLS--- 85
R CSL G FV TFD Y F G C+Y+L Q + + VS S
Sbjct: 391 RPCPGHCSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDGALMAVYDKSGVSHSETS 450
Query: 86 ----VYLGEFFDIHLFVNGTVTQGDQRVSMPYASKGLYLETEAGYYKLSGEAYGFVARID 141
VYL I + + VT + +PY ++ + + + + ++G +
Sbjct: 451 LVAVVYLSRQDKIVISQDEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMATSFGLELVVQ 510
Query: 142 GSGNFQ--VLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGEQW 199
FQ V + ++ +T GLCGNFN DDF T G F +SW +
Sbjct: 511 LRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTASLFVDSWRAGNCPAA 570
Query: 200 CERASPPSSSCNISSGEMQKGLWEQCQLLKSTSVFARCHPLVDPEPFVALCEKTLCECAG 259
ER + P C++S LL++ +VF RCH V+P PF C C
Sbjct: 571 LERETDP---CSMSQLNKVCAETHCSMLLRTGTVFERCHATVNPAPFYKRCVYQACNYEE 627
Query: 260 GLECACPALLEYARTCAQEGMVLYGW-TDHSACSPVCPAGMEYRQCVSPCARTCQSLHIN 318
C AL +Y C+ G++L+GW + C+ C + C RTC SL
Sbjct: 628 TFPHICAALGDYVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFSYNSQACERTCLSLSDR 687
Query: 319 EM-CQERC--VDGCSCPEGQLLDE-GLCVESTECPCVHSGKRY-PPGTSLSRDCNTCICR 373
C VDGC+CP+G L++ G CV +CPC+ G ++ S + TC C
Sbjct: 688 ATECHHSAVPVDGCNCPDGTYLNQKGECVRKAQCPCILEGYKFILAEQSTVINGITCHCI 747
Query: 374 NSQWIC 379
N + C
Sbjct: 748 NGRLSC 753
Score = 112 bits (280), Expect = 5e-24
Identities = 130/551 (23%), Positives = 199/551 (36%), Gaps = 100/551 (18%)
Query: 1938 ETCGC---RWTC---PCV--CTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKEQDLEVILH 1989
+TC C RW C PC C+ + TFD + ++ G+C+Y+L Q+ + + L
Sbjct: 377 QTCRCTLGRWVCTERPCPGHCSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDGALM 436
Query: 1990 NGACSPGARQGCMKSIEVKHSAL--SVELHSDMEVTVNGRLVSVPYVGGNMEVNVYGAIM 2047
G + V + + + + D VT NG +PY N+ V
Sbjct: 437 AVYDKSGVSHSETSLVAVVYLSRQDKIVISQDEVVTNNGEAKWLPYKTRNITV------- 489
Query: 2048 HEVRFNHLG-HIFTFTPQNNEFQLQLSP---------KTFASKTYGLCGICDENGANDFM 2097
F H+ T E +QL P F +T GLCG + + +DF
Sbjct: 490 ----FRQTSTHLQMATSFGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFT 545
Query: 2098 LRDGTVTTDWKTLVQEW-------TVQRPGQTCQPILEEQCLVPDSSHCQVLLL--PLFA 2148
G V W ++R C + + V +HC +LL +F
Sbjct: 546 TSMGIAEGTASLFVDSWRAGNCPAALERETDPCS--MSQLNKVCAETHCSMLLRTGTVFE 603
Query: 2149 ECHKVLAPATFYAICQQDSCHQEQ----VCEVIASYAHLCRTNGVCV-DWRTP-DFCAMS 2202
CH + PA FY C +C+ E+ +C + Y H C GV + WR+ D C +
Sbjct: 604 RCHATVNPAPFYKRCVYQACNYEETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCTIP 663
Query: 2203 CPPSLVYNHCEHGCPRHC---DGNVSSCGDH--PSEGCFCPPDKVM-LEGSCVPEEACTQ 2256
C + +++ C R C + C P +GC CP + +G CV + C
Sbjct: 664 CTGNTTFSYNSQACERTCLSLSDRATECHHSAVPVDGCNCPDGTYLNQKGECVRKAQC-P 722
Query: 2257 CIGEDGVQHQFLEAWVPDHQPCQICTCLSGRKVNCTTQP---CPTAKAP-TCGLCEVARL 2312
CI E ++F+ A C C++GR ++C +P + +AP T C +
Sbjct: 723 CILEG---YKFILAEQSTVINGITCHCINGR-LSCPQRPQMFLASCQAPKTFKSCSQSSE 778
Query: 2313 RQNADQCCPEYECVCDPVSCDLPPVPHCERGLQPTLTNPGECRPNFTCACRKEECKRVSP 2372
+ C P + + V+C PT PG C C + +
Sbjct: 779 NKFGAACAPTCQMLATGVAC------------VPTKCEPG-------CVCAEGLYENADG 819
Query: 2373 PSCPPHRLPTLRKTQCCDEYECACNCVNSTVSCPLGYLASTATNDCGCT--TTTCLPDKV 2430
PP C C S VS P G T C C+ C
Sbjct: 820 QCVPPEE----------------CPCEFSGVSYPGGAELHTDCRTCSCSRGRWACQQGTH 863
Query: 2431 CVHRSTIYPVG 2441
C T+Y G
Sbjct: 864 CPSTCTLYGEG 874
Score = 112 bits (279), Expect = 7e-24
Identities = 104/401 (25%), Positives = 153/401 (38%), Gaps = 68/401 (16%)
Query: 1939 TCGC---RWTC------PCVCTGSSTRHIVTFDGQNFKLTGSCSYVL------FQNKEQD 1983
TC C RW C P CT H++TFDGQ F G+C Y+L + +
Sbjct: 848 TCSCSRGRWACQQGTHCPSTCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQPT 907
Query: 1984 LEVILHNGACSPGARQGCMKSIEVKHSALSVELHSDMEVTVNGRLVSVPYVGGNMEVNVY 2043
+++ N C + C ++I++ LSV L +D TV G P+V +
Sbjct: 908 FKILTENVICG-NSGVTCSRAIKIFLGGLSVVL-ADRNYTVTGE---EPHVQLGVTP--- 959
Query: 2044 GAIMHEVRFNHLGHIFTFTPQNNEFQLQLS-PKTFASKTYGLCGICDENGANDFMLRDGT 2102
GA+ V + G N + + + GLCG + N +DF R
Sbjct: 960 GALSLVVDISIPGRYNLTLIWNRHMTILIRIARASQDPLCGLCGNFNGNMKDDFETRSRY 1019
Query: 2103 VTTDWKTLVQEWTVQRPGQTCQPILEEQCLVPD------------SSHCQVLLLPLFAEC 2150
V + LV W P+ + V D C V+ FA C
Sbjct: 1020 VASSELELVNSWKES-------PLCGDVSFVTDPCSLNAFRRSWAERKCSVINSQTFATC 1072
Query: 2151 HKVLAPATFYAICQQDSC------HQEQVCEVIASYAHLCRTNGVCVDWRTPDFCAMSCP 2204
H + +Y C +D+C E +C+ +A+YA C GVCVDWRTP FC + C
Sbjct: 1073 HSKVYHLPYYEACVRDACGCDSGGDCECLCDAVAAYAQACLDKGVCVDWRTPAFCPIYC- 1131
Query: 2205 PSLVYNHCEHGCPRHCDGNVSSCGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQ 2264
H + G + ++C H + C CP + GS + E C C ++
Sbjct: 1132 -GFYNTHTQDGHGEYQYTQEANCTWH-YQPCLCPSQPQSVPGSNI--EGCYNCSQDEYF- 1186
Query: 2265 HQFLEAWVPDHQPCQICTCLSGRKVNCTTQPCPTAKAPTCG 2305
DH+ C+ T QP T + PT G
Sbjct: 1187 ---------DHEEGVCVPCMP----PTTPQPPTTPQLPTTG 1214
Score = 94.7 bits (234), Expect = 1e-18
Identities = 98/372 (26%), Positives = 147/372 (39%), Gaps = 46/372 (12%)
Query: 1950 CTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKEQDLEVILHNGACSPGARQGCMKSIEVKH 2009
C+ H TFD + +G+C+Y+ + S R+G SI
Sbjct: 45 CSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPTF------SVQLRRGPDGSI---- 94
Query: 2010 SALSVELHSDMEVTVNGRLVSV--------PYVGGNMEVNVYGAIMHEVRFN-HLGHIFT 2060
S + VEL + + VTV+ ++SV PY +++ +G + V L
Sbjct: 95 SRIIVELGASV-VTVSEAIISVKDIGVISLPYTSNGLQITPFGQSVRLVAKQLELELEVV 153
Query: 2061 FTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTVQRPG 2120
+ P ++ + L + + + GLCG D N+F+ +G K + + PG
Sbjct: 154 WGPDSH--LMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFLEPHKFAALQ-KLDDPG 210
Query: 2121 QTCQPILEEQCLVPDSSH---CQVLLLPLFAECHKVLAPATFYAICQQDSCH------QE 2171
+ C V + H C LL + EC P F CQ D Q
Sbjct: 211 EICTFQDIPSTHVRQAQHARICTQLLTLVAPECSVSKEP--FVLSCQADVAAAPQPGPQN 268
Query: 2172 QVCEVIASYAHLCRTNGVCVD-WRTPDFCAMS-CPPSLVYNHCEHGCPRHCDGNVSSCGD 2229
C ++ Y+ C G V WR+P C++ CP + VY C C + C SC
Sbjct: 269 SSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSACVKTCSNPQHSCSS 328
Query: 2230 HPSEGCFCPPDKVMLEGS----CVPEEACTQCIGEDGVQHQFLEAWVPDHQPCQICTCLS 2285
+ GCFCP V+ + S CVP C C+ G + E + CQ C C
Sbjct: 329 SCTFGCFCPEGTVLNDLSNNHTCVPVTQC-PCV-LHGAMYAPGEVTI---AACQTCRCTL 383
Query: 2286 GRKVNCTTQPCP 2297
GR V CT +PCP
Sbjct: 384 GRWV-CTERPCP 394
Score = 92.0 bits (227), Expect = 7e-18
Identities = 97/369 (26%), Positives = 146/369 (39%), Gaps = 48/369 (13%)
Query: 22 CAEGTRGRSSTARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGC-----QKRSFSIIGD- 75
C +GT S+ C+L+G V TFDG + F G C Y+LA + +F I+ +
Sbjct: 858 CQQGTHCPST---CTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQPTFKILTEN 914
Query: 76 ---FQNGKRVS--LSVYLGEFFDIHLFVNGTVTQGDQRVSMPYASKGLYLETEAGYYKLS 130
+G S + ++LG + N TVT + V + L L + +
Sbjct: 915 VICGNSGVTCSRAIKIFLGGLSVVLADRNYTVTGEEPHVQLGVTPGALSLVVD---ISIP 971
Query: 131 GEAYGFVARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANS 190
G Y + + ++ + CGLCGNFN +DDF T+ + S + NS
Sbjct: 972 GR-YNLTLIWNRHMTILIRIARASQDPLCGLCGNFNGNMKDDFETRSRYVASSELELVNS 1030
Query: 191 WALSSGEQWCERASPPSSSCNISSGEMQKGLWEQCQLLKSTSVFARCHPLVDPEPFVALC 250
W S C S + C++++ + +C ++ S FA CH V P+ C
Sbjct: 1031 WKES---PLCGDVSFVTDPCSLNAFR-RSWAERKCSVINS-QTFATCHSKVYHLPYYEAC 1085
Query: 251 EKTLCEC--AGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVC----------PAG 298
+ C C G EC C A+ YA+ C +G V W + C C
Sbjct: 1086 VRDACGCDSGGDCECLCDAVAAYAQACLDKG-VCVDWRTPAFCPIYCGFYNTHTQDGHGE 1144
Query: 299 MEYRQ---CV---SPCARTCQSLHINEMCQERCVDGCSCPEGQLLDEGLCVESTECPCVH 352
+Y Q C PC Q + E C + CS E +EG+CV PC+
Sbjct: 1145 YQYTQEANCTWHYQPCLCPSQPQSVPGSNIEGCYN-CSQDEYFDHEEGVCV-----PCMP 1198
Query: 353 SGKRYPPGT 361
PP T
Sbjct: 1199 PTTPQPPTT 1207
Score = 42.4 bits (98), Expect = 0.007
Identities = 40/161 (24%), Positives = 63/161 (39%), Gaps = 32/161 (19%)
Query: 1091 CESIGDCACFCDTIAAYAHVCAQHGKVVTWRTATL------CPQ-------SCEE-RNLR 1136
C C C + Y + A+ V+ T CPQ SC+ + +
Sbjct: 715 CVRKAQCPCILE---GYKFILAEQSTVINGITCHCINGRLSCPQRPQMFLASCQAPKTFK 771
Query: 1137 ENGYECEWRYNS-CAPACQVTCQHPEPLAC-PVQCVEGCHAHCPPGKILDELLQTCVDPE 1194
E ++ + CAP CQ+ +AC P +C GC C G + + CV PE
Sbjct: 772 SCSQSSENKFGAACAPTCQMLATG---VACVPTKCEPGCV--CAEG-LYENADGQCVPPE 825
Query: 1195 DCPVCEVAGRRFASGKKVTLNPSDPEHCQICHCDVVNLTCE 1235
+CP CE +G + G ++ + C+ C C C+
Sbjct: 826 ECP-CEFSGVSYPGGAELHTD------CRTCSCSRGRWACQ 859
Score = 42.4 bits (98), Expect = 0.007
Identities = 21/71 (29%), Positives = 33/71 (46%), Gaps = 4/71 (5%)
Query: 2745 VDIHYCQGKCASKAMYSIDINDVQDQCSCCSPTRTEPMQVALHCTNGSVVYHEVLNAME- 2803
V + C+G C S A ++I V +CSCC P + Q+ L C + S ++ ++
Sbjct: 2367 VTVTRCEGACISAASFNIITQQVDARCSCCRPLHSYEQQLELPCPDPSTPGRRLVLTLQV 2426
Query: 2804 ---CKCSPRKC 2811
C CS C
Sbjct: 2427 FSHCVCSSVAC 2437
Score = 41.6 bits (96), Expect = 0.011
Identities = 62/253 (24%), Positives = 85/253 (33%), Gaps = 54/253 (21%)
Query: 2233 EGCFCPPDK-VMLEGSCVPEEACTQCIGEDGVQHQFLEAWVPDHQPCQICTCLSGRKVNC 2291
EG F P K L+ P E CT V Q +ICT L +
Sbjct: 191 EGKFLEPHKFAALQKLDDPGEICTF--------QDIPSTHVRQAQHARICTQL----LTL 238
Query: 2292 TTQPCPTAKAPTCGLCE--VARLRQNADQ-----CCPEYECVCDPVSCDLPPVPHCERGL 2344
C +K P C+ VA Q Q EY C V PV R
Sbjct: 239 VAPECSVSKEPFVLSCQADVAAAPQPGPQNSSCATLSEYSRQCSMVG---QPV---RRWR 292
Query: 2345 QPTLTNPGECRPNFTCACRKEECKRVSPPSCPPHRLPTLRKTQCCDEYECACNCVNSTVS 2404
P L + G+C N +EC +C ++ C+ +C
Sbjct: 293 SPGLCSVGQCPANQVY----QECGSACVKTCSN------------PQHSCSSSCTFGCF- 335
Query: 2405 CPLGYLASTATNDCGCTTTTCLPDKVCVHRSTIYPVGQFWEEGCDVCTCTDMEDAVMGLR 2464
CP G + + +N+ C T P CV +Y G+ C C CT +G
Sbjct: 336 CPEGTVLNDLSNNHTCVPVTQCP---CVLHGAMYAPGEVTIAACQTCRCT------LGRW 386
Query: 2465 VAQCSQKPCEDSC 2477
V C+++PC C
Sbjct: 387 V--CTERPCPGHC 397
Score = 34.7 bits (78), Expect = 1.4
Identities = 19/51 (37%), Positives = 25/51 (49%), Gaps = 7/51 (13%)
Query: 2557 CPSGFQLS--CKTSACCPSCRCERMEACMLNGTVIGPGKTVMIDVCTTCRC 2605
CP G L+ C P +C C+L+G + PG+ V I C TCRC
Sbjct: 336 CPEGTVLNDLSNNHTCVPVTQCP----CVLHGAMYAPGE-VTIAACQTCRC 381
>gi|239750277 PREDICTED: hypothetical protein XP_002347351 [Homo
sapiens]
Length = 2134
Score = 511 bits (1316), Expect = e-144
Identities = 303/964 (31%), Positives = 438/964 (45%), Gaps = 78/964 (8%)
Query: 265 CPALLEYARTCAQEGMVLY-GWTDHS--ACSPV-CPAGMEYRQCVSPCARTCQSLHINEM 320
C E +R CA +G + W S C CP Y++C TC + +
Sbjct: 728 CDTYSELSRLCASDGPGTFESWRSDSDVVCETQRCPEQHIYKECGPSNPATCSN--VAPF 785
Query: 321 CQERCVDGCSCPEGQLLDE----GLCVESTECPCVHSGKRYPPGTSLSRDCNT-CICRNS 375
CV GC+CPEG LLD+ G CV ECPC SG Y PG C + C C+++
Sbjct: 786 QDSECVSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPGEVREGPCGSQCTCQDA 845
Query: 376 QWICSNEECPGECLVTGQSHFKSFDNRYFTFSGICQYLLARDCQDHSFSIVIETVQCADD 435
+W C+ CPG C V G S +FD + F G C +L + +SI +E C
Sbjct: 846 KWSCTEALCPGRCKVEGSS-LTTFDGVKYNFPGNCHFLAVHN---EDWSISVELRPCPSG 901
Query: 436 RDAVCTRSVTVRLPGLHNSLVKL-----KHGAGVAMDGQDVQLPLLKGDLRIQHTVTASV 490
+ C SVT+ L NS V + V D Q ++I + ++ +
Sbjct: 902 QTGTCLNSVTLLL----NSSVPVDKYVFNSDGTVTNDKIRNQGYYYSDKIQIFNASSSYL 957
Query: 491 RLS--YGEDLQMDWDGRGRLLVKLSPVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVED 548
++ + LQ+ +L V + P T GLCG+YN DDF++ + E +
Sbjct: 958 QVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQA 1017
Query: 549 FGNAWKLHGDCQDLQKQHSDPCALNPRMTRFSEEACAVL--TSPTFEACHRAVSPLPYLR 606
F N+W++ K + C ++ +F+E C +L +S +CH V+P PY
Sbjct: 1018 FANSWEM----MSCPKGNPSSC-ISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHE 1072
Query: 607 NCRYDVCSCSDGRECLCGALASYAAACAGRGVRVAWREPGRCELNCPKGQVYLQCGTPCN 666
C+ C+C + ++CLC L +Y ACA + + G CE +CP G V+ CN
Sbjct: 1073 ECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEHSCPSGLVFKYNVKACN 1132
Query: 667 LTCRSLSYPDEECN--EACLEGCFCPPGLYMDERGDCVPKAQCPCYYDGEIFQPEDIFSD 724
+CRSLS D C+ + ++GC CP +Y + G+CV K+QC CY + E+ QP +
Sbjct: 1133 SSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHI 1192
Query: 725 HHTMCYCEDGFMHCTMSGVPGSLLPDAVLSSPLSHRSKRSLSCRPPMVKLVCPADNLRAE 784
C C DG + C + D L + + C P +
Sbjct: 1193 DDNKCVCRDGILLCQIP-------IDLTLQN--CSGGAEYVDCSDPKAQR---------- 1233
Query: 785 GLECTKTCQNYDLECM--SMGCVSGCLCPPGMVRHENR-CVALERCPCFHQGKEYAPGET 841
+TC ++ ++ C GC CP GMVR+ CV CPC G+EY G
Sbjct: 1234 --RTNRTCSTRNIPVFDENLPCKRGCFCPEGMVRNSKGICVFPNDCPCSFGGREYDEGSV 1291
Query: 842 VKIGCNTCVCRDRKWNCTDHVCDATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSN 901
+GCN C C W+CT + C C G H TFDG Y F G CQY ++DYCG
Sbjct: 1292 TSVGCNECTCIKGSWSCTQNECQTICHIYGEGHVRTFDGKSYSFDGLCQYSFLEDYCGHE 1351
Query: 902 PGTFRILVGNKGCSHPSVKCKKRVTILVEGGEIELFDGEVNV------KRPMKDETHFEV 955
GTFRIL + C + C +++ + + I L DG+V K+ + + +
Sbjct: 1352 NGTFRILTESVPCCEDGLTCSRKIIVAFQDQNIVLQDGKVTAVKSTESKKCELNANAYSI 1411
Query: 956 VESGRYIILLLGKALSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVE 1015
G Y+IL + V+WD++ +SV+L + KVCGLCGN +G +D T+ V
Sbjct: 1412 HTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVA 1471
Query: 1016 EDPVDFGNSWKVSSQCADT--RKVPLDSSPATCHNNIMKQTMVDSSCRILTSDVFQDCNK 1073
++FGNSWK S +C+DT + P DS+P + C IL F+DC+
Sbjct: 1472 SGALEFGNSWKTSQECSDTVAQTFPCDSNPYC-------KAWAVRKCEILRDSTFRDCHN 1524
Query: 1074 LVDPEPYLDVCIYDTCSCESIGDCACFCDTIAAYAHVCAQHGKVVTWRTATLCPQSCEER 1133
VDP Y DVCI + C+C+ G FC +A YA C+ G V+WR LCP C+
Sbjct: 1525 KVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCVSWRKPNLCPVYCDYY 1584
Query: 1134 NLRENGYECEWRYNSCAPACQVTCQHPEPLACPVQCVEGCHAHCP-PGKILDELLQTCVD 1192
N EC W Y C TC+ +EGC+A CP LDE CV
Sbjct: 1585 NAPG---ECRWHYEPCGTVTAKTCKDQLVGQKFSSLLEGCYAKCPDSAPYLDENTMKCVS 1641
Query: 1193 PEDC 1196
+C
Sbjct: 1642 LSEC 1645
Score = 280 bits (715), Expect = 2e-74
Identities = 239/835 (28%), Positives = 345/835 (41%), Gaps = 143/835 (17%)
Query: 34 RCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRSFSIIGDF------QNGKRV-SLSV 86
RC + GS + TFDG Y+F G C +L +SI + Q G + S+++
Sbjct: 857 RCKVEGSS-LTTFDGVKYNFPGNCHFLAV---HNEDWSISVELRPCPSGQTGTCLNSVTL 912
Query: 87 YLGEFFDIHLFV---NGTVTQGDQRVSMPYASKGLYLETEAGYYKLSGEAYGFVA---RI 140
L + +V +GTVT R Y S + + + Y L E Y V +I
Sbjct: 913 LLNSSVPVDKYVFNSDGTVTNDKIRNQGYYYSDKIQIFNASSSY-LQVETYFHVKLQIQI 971
Query: 141 DGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSS----- 195
V + F T GLCG++N AEDDFM+ + L FANSW + S
Sbjct: 972 VPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMSCPKGN 1031
Query: 196 --------GEQWCER-------ASPPSSSCNISSGEMQKGLWEQCQLLKST---SVFARC 237
E++ ER +S P +SC+ K E+C+ T S C
Sbjct: 1032 PSSCISIEKEKFAERHCGILLDSSGPLASCHPIVNP--KPYHEECKKYTCTCENSQDCLC 1089
Query: 238 HPL-------VDPEPFVALCEKTLCE--CAGGL---------ECACPALLEYARTCAQEG 279
L + E ++ LCE C GL +C +L E R+C E
Sbjct: 1090 TILGNYVKACAEKETYIVGWRTGLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVED 1149
Query: 280 MVLYGWT------------------------------------DHSACS----------P 293
+ + G T D + C P
Sbjct: 1150 VPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDDNKCVCRDGILLCQIP 1209
Query: 294 V------CPAGMEYRQCVSPCA-----RTCQSLHINEMCQER-CVDGCSCPEGQLLD-EG 340
+ C G EY C P A RTC + +I + C GC CPEG + + +G
Sbjct: 1210 IDLTLQNCSGGAEYVDCSDPKAQRRTNRTCSTRNIPVFDENLPCKRGCFCPEGMVRNSKG 1269
Query: 341 LCVESTECPCVHSGKRYPPGTSLSRDCNTCICRNSQWICSNEECPGECLVTGQSHFKSFD 400
+CV +CPC G+ Y G+ S CN C C W C+ EC C + G+ H ++FD
Sbjct: 1270 ICVFPNDCPCSFGGREYDEGSVTSVGCNECTCIKGSWSCTQNECQTICHIYGEGHVRTFD 1329
Query: 401 NRYFTFSGICQYLLARDCQDH---SFSIVIETVQCADDRDAVCTRSVTVRLPGLHNSLVK 457
+ ++F G+CQY D H +F I+ E+V C +D C+R + V + +
Sbjct: 1330 GKSYSFDGLCQYSFLEDYCGHENGTFRILTESVPCCED-GLTCSRKIIV---AFQDQNIV 1385
Query: 458 LKHGAGVAMDGQDVQLPLLKGDLRIQHTVTASVRLSYGEDLQMDWDGRGRLLVKLSPVYA 517
L+ G A+ + + L + HTV + L + + + WD RL V L P +
Sbjct: 1386 LQDGKVTAVKSTESKKCELNANAYSIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWN 1445
Query: 518 GKTCGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWKLHGDCQDLQKQHSDPCALNPRMT 577
GK CGLCGN NG+ DDF T +FGN+WK +C D Q + PC NP
Sbjct: 1446 GKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTVAQ-TFPCDSNPYCK 1504
Query: 578 RFSEEACAVLTSPTFEACHRAVSPLPYLRNCRYDVCSCS-DGREC-LCGALASYAAACAG 635
++ C +L TF CH V P Y C + C+C +G+ C A+A YA AC+
Sbjct: 1505 AWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSA 1564
Query: 636 RGVRVAWREPGRCELNCPKGQV-------YLQCGTPCNLTCRSLSYPDEECNEACLEGCF 688
GV V+WR+P C + C Y CGT TC+ + + LEGC+
Sbjct: 1565 VGVCVSWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVGQK--FSSLLEGCY 1622
Query: 689 --CPPGL-YMDERG-DCVPKAQCPCYYDGEIFQPEDIFSDHHTMCYCEDGFMHCT 739
CP Y+DE CV ++C C+Y+ I I + CYC G + C+
Sbjct: 1623 AKCPDSAPYLDENTMKCVSLSECSCFYNDVIPAGGVIEDNCGRTCYCIAGQLECS 1677
Score = 92.4 bits (228), Expect = 6e-18
Identities = 96/386 (24%), Positives = 158/386 (40%), Gaps = 57/386 (14%)
Query: 1923 LRPSCPNSQS-----PVKVEE-----TCGC---RWTCP-------CVCTGSSTRHIVTFD 1962
L+ CP S P +V E C C +W+C C GSS + TFD
Sbjct: 813 LKAECPCESSGTVYQPGEVREGPCGSQCTCQDAKWSCTEALCPGRCKVEGSS---LTTFD 869
Query: 1963 GQNFKLTGSCSYVLFQNKEQDLEVILHNGACSPGARQGCMKSIEVK-HSALSVE---LHS 2018
G + G+C ++ N++ + V L C G C+ S+ + +S++ V+ +S
Sbjct: 870 GVKYNFPGNCHFLAVHNEDWSISVELR--PCPSGQTGTCLNSVTLLLNSSVPVDKYVFNS 927
Query: 2019 DMEVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHLGHIFTFTPQNNEFQLQLS-PKTF 2077
D VT N ++ + Y + ++ ++ A ++ H+ QL +S P
Sbjct: 928 DGTVT-NDKIRNQGYYYSD-KIQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQ 985
Query: 2078 ASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTVQRPGQTCQPILEEQCLVPDSS 2137
+ T GLCG + +DFM + + W + +C C+ +
Sbjct: 986 FTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMM----SCPKGNPSSCISIEKE 1041
Query: 2138 -----HCQVLLL---PLFAECHKVLAPATFYAICQQDSC----HQEQVCEVIASYAHLCR 2185
HC +LL PL A CH ++ P ++ C++ +C Q+ +C ++ +Y C
Sbjct: 1042 KFAERHCGILLDSSGPL-ASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACA 1100
Query: 2186 TNGV-CVDWRTPDFCAMSCPPSLVYNHCEHGCPRHC---DGNVSSCG--DHPSEGCFCPP 2239
V WRT C SCP LV+ + C C SC D P +GC CP
Sbjct: 1101 EKETYIVGWRT-GLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPD 1159
Query: 2240 DKVM-LEGSCVPEEACTQCIGEDGVQ 2264
EG+CV + C I ++ +Q
Sbjct: 1160 AMYQNNEGNCVLKSQCDCYINDEVMQ 1185
Score = 81.6 bits (200), Expect = 1e-14
Identities = 58/203 (28%), Positives = 88/203 (43%), Gaps = 23/203 (11%)
Query: 554 KLHGDCQDLQKQHSDPCALNPRMTRFSEEACAVLTSPTFEACHR-AVSPLPYLRNCRYDV 612
K+ GDC + + + C + C + FE C + A Y C +
Sbjct: 666 KIPGDCPNAVGKSYEVC-------EDGIQHCNKIIGTYFEKCGKVAALSNDYKMICIDEY 718
Query: 613 CSCSDGRECLCGALASYAAACA--GRGVRVAWREPGR--CELN-CPKGQVYLQCGTPCNL 667
C D + C + + CA G G +WR CE CP+ +Y +CG
Sbjct: 719 CQTRD-KTSTCDTYSELSRLCASDGPGTFESWRSDSDVVCETQRCPEQHIYKECGPSNPA 777
Query: 668 TCRSLS-YPDEECNEACLEGCFCPPGLYMD---ERGDCVPKAQCPCYYDGEIFQPEDIFS 723
TC +++ + D EC + GC CP G +D E+G CV KA+CPC G ++QP ++
Sbjct: 778 TCSNVAPFQDSEC----VSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPGEVRE 833
Query: 724 DH-HTMCYCEDGFMHCTMSGVPG 745
+ C C+D CT + PG
Sbjct: 834 GPCGSQCTCQDAKWSCTEALCPG 856
Score = 78.2 bits (191), Expect = 1e-13
Identities = 67/310 (21%), Positives = 115/310 (37%), Gaps = 37/310 (11%)
Query: 1946 CPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQN----KEQDLEVILHNGACSPGARQGC 2001
C +C H+ TFDG+++ G C Y ++ + ++ + C C
Sbjct: 1313 CQTICHIYGEGHVRTFDGKSYSFDGLCQYSFLEDYCGHENGTFRILTESVPCCEDGLT-C 1371
Query: 2002 MKSIEVKHSALSVELHSDMEVTVNGRLVSVPYVGGNM-EVNVYGAIMHEVRFNHL----G 2056
+ I V ++ L +G++ +V E+N +H V +
Sbjct: 1372 SRKIIVAFQDQNIVLQ-------DGKVTAVKSTESKKCELNANAYSIHTVGLYLILKFQN 1424
Query: 2057 HIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTV 2116
I +N + L P + K GLCG + + +DF R +V + W
Sbjct: 1425 GIIVIWDKNTRLSVILDPN-WNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKT 1483
Query: 2117 QRP-----GQTCQPILEEQCLVPDSSHCQVLLLPLFAECHKVLAPATFYAICQQDSCHQE 2171
+ QT C C++L F +CH + P+ ++ +C +++C +
Sbjct: 1484 SQECSDTVAQTFPCDSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACD 1543
Query: 2172 Q------VCEVIASYAHLCRTNGVCVDWRTPDFCAMSCPPSLVYNHCEHGCPRHCDGNVS 2225
C +A YA C GVCV WR P+ C + C YN P C +
Sbjct: 1544 MEGKYLGFCTAVAMYAEACSAVGVCVSWRKPNLCPVYCD---YYN-----APGECRWHYE 1595
Query: 2226 SCGDHPSEGC 2235
CG ++ C
Sbjct: 1596 PCGTVTAKTC 1605
Score = 49.7 bits (117), Expect = 4e-05
Identities = 46/174 (26%), Positives = 64/174 (36%), Gaps = 20/174 (11%)
Query: 2138 HCQVLLLPLFAECHKVLAPATFYA-ICQQDSCH---QEQVCEVIASYAHLCRTNG--VCV 2191
HC ++ F +C KV A + Y IC + C + C+ + + LC ++G
Sbjct: 688 HCNKIIGTYFEKCGKVAALSNDYKMICIDEYCQTRDKTSTCDTYSELSRLCASDGPGTFE 747
Query: 2192 DWRTPD--FC-AMSCPPSLVYNHCEHGCPRHCDGNVSSCGDHPSEGCFCPP----DKVML 2244
WR+ C CP +Y C P C GC CP D +
Sbjct: 748 SWRSDSDVVCETQRCPEQHIYKECGPSNPATCSNVAPFQDSECVSGCTCPEGYLLDDIGE 807
Query: 2245 EGSCVPEEACTQCIGEDGVQHQFLEAWVPDHQPC-QICTCLSGRKVNCTTQPCP 2297
+G CV + C G +Q E PC CTC K +CT CP
Sbjct: 808 KGKCVLKAECP--CESSGTVYQPGEV---REGPCGSQCTC-QDAKWSCTEALCP 855
Score = 32.7 bits (73), Expect = 5.2
Identities = 18/65 (27%), Positives = 28/65 (43%), Gaps = 1/65 (1%)
Query: 386 GECLVTGQSHFKSFDNRYFTFSGICQYLLARDCQDHSFSIVIETVQCADDRDAVCTRSVT 445
GE + +KSF+ R F F C Y R C + IE ++ +DR +
Sbjct: 606 GEISTWSKGAYKSFNGRIFFFESSCPYTFCRHCIESGGDFNIE-IKRNNDRQDINEHIAN 664
Query: 446 VRLPG 450
++PG
Sbjct: 665 SKIPG 669
>gi|239744587 PREDICTED: hypothetical protein XP_002343203 [Homo
sapiens]
Length = 2134
Score = 511 bits (1316), Expect = e-144
Identities = 303/964 (31%), Positives = 438/964 (45%), Gaps = 78/964 (8%)
Query: 265 CPALLEYARTCAQEGMVLY-GWTDHS--ACSPV-CPAGMEYRQCVSPCARTCQSLHINEM 320
C E +R CA +G + W S C CP Y++C TC + +
Sbjct: 728 CDTYSELSRLCASDGPGTFESWRSDSDVVCGTQRCPEQHIYKECGPSNPATCSN--VAPF 785
Query: 321 CQERCVDGCSCPEGQLLDE----GLCVESTECPCVHSGKRYPPGTSLSRDCNT-CICRNS 375
CV GC+CPEG LLD+ G CV ECPC SG Y PG C + C C+++
Sbjct: 786 QDSECVSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPGEVREGPCGSQCTCQDA 845
Query: 376 QWICSNEECPGECLVTGQSHFKSFDNRYFTFSGICQYLLARDCQDHSFSIVIETVQCADD 435
+W C+ CPG C V G S +FD + F G C +L + +SI +E C
Sbjct: 846 KWSCTEALCPGRCKVEGSS-LTTFDGVKYNFPGNCHFLAVHN---EDWSISVELRPCPSG 901
Query: 436 RDAVCTRSVTVRLPGLHNSLVKL-----KHGAGVAMDGQDVQLPLLKGDLRIQHTVTASV 490
+ C SVT+ L NS V + V D Q ++I + ++ +
Sbjct: 902 QTGTCLNSVTLLL----NSSVPVDKYVFNSDGTVTNDKIRNQGYYYSDKIQIFNASSSYL 957
Query: 491 RLS--YGEDLQMDWDGRGRLLVKLSPVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVED 548
++ + LQ+ +L V + P T GLCG+YN DDF++ + E +
Sbjct: 958 QVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQA 1017
Query: 549 FGNAWKLHGDCQDLQKQHSDPCALNPRMTRFSEEACAVL--TSPTFEACHRAVSPLPYLR 606
F N+W++ K + C ++ +F+E C +L +S +CH V+P PY
Sbjct: 1018 FANSWEM----MSCPKGNPSSC-ISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHE 1072
Query: 607 NCRYDVCSCSDGRECLCGALASYAAACAGRGVRVAWREPGRCELNCPKGQVYLQCGTPCN 666
C+ C+C + ++CLC L +Y ACA + + G CE +CP G V+ CN
Sbjct: 1073 ECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEHSCPSGLVFKYNVKACN 1132
Query: 667 LTCRSLSYPDEECN--EACLEGCFCPPGLYMDERGDCVPKAQCPCYYDGEIFQPEDIFSD 724
+CRSLS D C+ + ++GC CP +Y + G+CV K+QC CY + E+ QP +
Sbjct: 1133 SSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHI 1192
Query: 725 HHTMCYCEDGFMHCTMSGVPGSLLPDAVLSSPLSHRSKRSLSCRPPMVKLVCPADNLRAE 784
C C DG + C + D L + + C P +
Sbjct: 1193 DDNKCVCRDGILLCQIP-------IDLTLQN--CSGGAEYVDCSDPKAQR---------- 1233
Query: 785 GLECTKTCQNYDLECM--SMGCVSGCLCPPGMVRHENR-CVALERCPCFHQGKEYAPGET 841
+TC ++ ++ C GC CP GMVR+ CV CPC G+EY G
Sbjct: 1234 --RTNRTCSTRNIPVFDENLPCKRGCFCPEGMVRNSKGICVFPNDCPCSFGGREYDEGSV 1291
Query: 842 VKIGCNTCVCRDRKWNCTDHVCDATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSN 901
+GCN C C W+CT + C C G H TFDG Y F G CQY ++DYCG
Sbjct: 1292 TSVGCNECTCIKGSWSCTQNECQTICHIYGEGHVRTFDGKSYSFDGLCQYSFLEDYCGHE 1351
Query: 902 PGTFRILVGNKGCSHPSVKCKKRVTILVEGGEIELFDGEVNV------KRPMKDETHFEV 955
GTFRIL + C + C +++ + + I L DG+V K+ + + +
Sbjct: 1352 NGTFRILTESVPCCEDGLTCSRKIIVAFQDQNIVLQDGKVTAVKSTESKKCELNANAYSI 1411
Query: 956 VESGRYIILLLGKALSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVE 1015
G Y+IL + V+WD++ +SV+L + KVCGLCGN +G +D T+ V
Sbjct: 1412 HTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVA 1471
Query: 1016 EDPVDFGNSWKVSSQCADT--RKVPLDSSPATCHNNIMKQTMVDSSCRILTSDVFQDCNK 1073
++FGNSWK S +C+DT + P DS+P + C IL F+DC+
Sbjct: 1472 SGALEFGNSWKTSQECSDTVAQTFPCDSNPYC-------KAWAVRKCEILRDSTFRDCHN 1524
Query: 1074 LVDPEPYLDVCIYDTCSCESIGDCACFCDTIAAYAHVCAQHGKVVTWRTATLCPQSCEER 1133
VDP Y DVCI + C+C+ G FC +A YA C+ G V+WR LCP C+
Sbjct: 1525 KVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCVSWRKPNLCPVYCDYY 1584
Query: 1134 NLRENGYECEWRYNSCAPACQVTCQHPEPLACPVQCVEGCHAHCP-PGKILDELLQTCVD 1192
N EC W Y C TC+ +EGC+A CP LDE CV
Sbjct: 1585 NAPG---ECRWHYEPCGTVTAKTCKDQLVGQKFSSLLEGCYAKCPDSAPYLDENTMKCVS 1641
Query: 1193 PEDC 1196
+C
Sbjct: 1642 LSEC 1645
Score = 280 bits (715), Expect = 2e-74
Identities = 239/835 (28%), Positives = 345/835 (41%), Gaps = 143/835 (17%)
Query: 34 RCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRSFSIIGDF------QNGKRV-SLSV 86
RC + GS + TFDG Y+F G C +L +SI + Q G + S+++
Sbjct: 857 RCKVEGSS-LTTFDGVKYNFPGNCHFLAV---HNEDWSISVELRPCPSGQTGTCLNSVTL 912
Query: 87 YLGEFFDIHLFV---NGTVTQGDQRVSMPYASKGLYLETEAGYYKLSGEAYGFVA---RI 140
L + +V +GTVT R Y S + + + Y L E Y V +I
Sbjct: 913 LLNSSVPVDKYVFNSDGTVTNDKIRNQGYYYSDKIQIFNASSSY-LQVETYFHVKLQIQI 971
Query: 141 DGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSS----- 195
V + F T GLCG++N AEDDFM+ + L FANSW + S
Sbjct: 972 VPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMSCPKGN 1031
Query: 196 --------GEQWCER-------ASPPSSSCNISSGEMQKGLWEQCQLLKST---SVFARC 237
E++ ER +S P +SC+ K E+C+ T S C
Sbjct: 1032 PSSCISIEKEKFAERHCGILLDSSGPLASCHPIVNP--KPYHEECKKYTCTCENSQDCLC 1089
Query: 238 HPL-------VDPEPFVALCEKTLCE--CAGGL---------ECACPALLEYARTCAQEG 279
L + E ++ LCE C GL +C +L E R+C E
Sbjct: 1090 TILGNYVKACAEKETYIVGWRTGLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVED 1149
Query: 280 MVLYGWT------------------------------------DHSACS----------P 293
+ + G T D + C P
Sbjct: 1150 VPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDDNKCVCRDGILLCQIP 1209
Query: 294 V------CPAGMEYRQCVSPCA-----RTCQSLHINEMCQER-CVDGCSCPEGQLLD-EG 340
+ C G EY C P A RTC + +I + C GC CPEG + + +G
Sbjct: 1210 IDLTLQNCSGGAEYVDCSDPKAQRRTNRTCSTRNIPVFDENLPCKRGCFCPEGMVRNSKG 1269
Query: 341 LCVESTECPCVHSGKRYPPGTSLSRDCNTCICRNSQWICSNEECPGECLVTGQSHFKSFD 400
+CV +CPC G+ Y G+ S CN C C W C+ EC C + G+ H ++FD
Sbjct: 1270 ICVFPNDCPCSFGGREYDEGSVTSVGCNECTCIKGSWSCTQNECQTICHIYGEGHVRTFD 1329
Query: 401 NRYFTFSGICQYLLARDCQDH---SFSIVIETVQCADDRDAVCTRSVTVRLPGLHNSLVK 457
+ ++F G+CQY D H +F I+ E+V C +D C+R + V + +
Sbjct: 1330 GKSYSFDGLCQYSFLEDYCGHENGTFRILTESVPCCED-GLTCSRKIIV---AFQDQNIV 1385
Query: 458 LKHGAGVAMDGQDVQLPLLKGDLRIQHTVTASVRLSYGEDLQMDWDGRGRLLVKLSPVYA 517
L+ G A+ + + L + HTV + L + + + WD RL V L P +
Sbjct: 1386 LQDGKVTAVKSTESKKCELNANAYSIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWN 1445
Query: 518 GKTCGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWKLHGDCQDLQKQHSDPCALNPRMT 577
GK CGLCGN NG+ DDF T +FGN+WK +C D Q + PC NP
Sbjct: 1446 GKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTVAQ-TFPCDSNPYCK 1504
Query: 578 RFSEEACAVLTSPTFEACHRAVSPLPYLRNCRYDVCSCS-DGREC-LCGALASYAAACAG 635
++ C +L TF CH V P Y C + C+C +G+ C A+A YA AC+
Sbjct: 1505 AWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSA 1564
Query: 636 RGVRVAWREPGRCELNCPKGQV-------YLQCGTPCNLTCRSLSYPDEECNEACLEGCF 688
GV V+WR+P C + C Y CGT TC+ + + LEGC+
Sbjct: 1565 VGVCVSWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVGQK--FSSLLEGCY 1622
Query: 689 --CPPGL-YMDERG-DCVPKAQCPCYYDGEIFQPEDIFSDHHTMCYCEDGFMHCT 739
CP Y+DE CV ++C C+Y+ I I + CYC G + C+
Sbjct: 1623 AKCPDSAPYLDENTMKCVSLSECSCFYNDVIPAGGVIEDNCGRTCYCIAGQLECS 1677
Score = 92.4 bits (228), Expect = 6e-18
Identities = 96/386 (24%), Positives = 158/386 (40%), Gaps = 57/386 (14%)
Query: 1923 LRPSCPNSQS-----PVKVEE-----TCGC---RWTCP-------CVCTGSSTRHIVTFD 1962
L+ CP S P +V E C C +W+C C GSS + TFD
Sbjct: 813 LKAECPCESSGTVYQPGEVREGPCGSQCTCQDAKWSCTEALCPGRCKVEGSS---LTTFD 869
Query: 1963 GQNFKLTGSCSYVLFQNKEQDLEVILHNGACSPGARQGCMKSIEVK-HSALSVE---LHS 2018
G + G+C ++ N++ + V L C G C+ S+ + +S++ V+ +S
Sbjct: 870 GVKYNFPGNCHFLAVHNEDWSISVELR--PCPSGQTGTCLNSVTLLLNSSVPVDKYVFNS 927
Query: 2019 DMEVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHLGHIFTFTPQNNEFQLQLS-PKTF 2077
D VT N ++ + Y + ++ ++ A ++ H+ QL +S P
Sbjct: 928 DGTVT-NDKIRNQGYYYSD-KIQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQ 985
Query: 2078 ASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTVQRPGQTCQPILEEQCLVPDSS 2137
+ T GLCG + +DFM + + W + +C C+ +
Sbjct: 986 FTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMM----SCPKGNPSSCISIEKE 1041
Query: 2138 -----HCQVLLL---PLFAECHKVLAPATFYAICQQDSC----HQEQVCEVIASYAHLCR 2185
HC +LL PL A CH ++ P ++ C++ +C Q+ +C ++ +Y C
Sbjct: 1042 KFAERHCGILLDSSGPL-ASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACA 1100
Query: 2186 TNGV-CVDWRTPDFCAMSCPPSLVYNHCEHGCPRHC---DGNVSSCG--DHPSEGCFCPP 2239
V WRT C SCP LV+ + C C SC D P +GC CP
Sbjct: 1101 EKETYIVGWRT-GLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPD 1159
Query: 2240 DKVM-LEGSCVPEEACTQCIGEDGVQ 2264
EG+CV + C I ++ +Q
Sbjct: 1160 AMYQNNEGNCVLKSQCDCYINDEVMQ 1185
Score = 79.3 bits (194), Expect = 5e-14
Identities = 56/203 (27%), Positives = 86/203 (42%), Gaps = 23/203 (11%)
Query: 554 KLHGDCQDLQKQHSDPCALNPRMTRFSEEACAVLTSPTFEACHR-AVSPLPYLRNCRYDV 612
K+ GDC + + + C + C + FE C + A Y C +
Sbjct: 666 KIPGDCPNAVGKSYEVC-------EDGIQHCNKIIGTYFEKCGKVAALSNDYKMICIDEY 718
Query: 613 CSCSDGRECLCGALASYAAACA--GRGVRVAWREPGRCELN---CPKGQVYLQCGTPCNL 667
C D + C + + CA G G +WR CP+ +Y +CG
Sbjct: 719 CQTRD-KTSTCDTYSELSRLCASDGPGTFESWRSDSDVVCGTQRCPEQHIYKECGPSNPA 777
Query: 668 TCRSLS-YPDEECNEACLEGCFCPPGLYMD---ERGDCVPKAQCPCYYDGEIFQPEDIFS 723
TC +++ + D EC + GC CP G +D E+G CV KA+CPC G ++QP ++
Sbjct: 778 TCSNVAPFQDSEC----VSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPGEVRE 833
Query: 724 DH-HTMCYCEDGFMHCTMSGVPG 745
+ C C+D CT + PG
Sbjct: 834 GPCGSQCTCQDAKWSCTEALCPG 856
Score = 78.2 bits (191), Expect = 1e-13
Identities = 67/310 (21%), Positives = 115/310 (37%), Gaps = 37/310 (11%)
Query: 1946 CPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQN----KEQDLEVILHNGACSPGARQGC 2001
C +C H+ TFDG+++ G C Y ++ + ++ + C C
Sbjct: 1313 CQTICHIYGEGHVRTFDGKSYSFDGLCQYSFLEDYCGHENGTFRILTESVPCCEDGLT-C 1371
Query: 2002 MKSIEVKHSALSVELHSDMEVTVNGRLVSVPYVGGNM-EVNVYGAIMHEVRFNHL----G 2056
+ I V ++ L +G++ +V E+N +H V +
Sbjct: 1372 SRKIIVAFQDQNIVLQ-------DGKVTAVKSTESKKCELNANAYSIHTVGLYLILKFQN 1424
Query: 2057 HIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTV 2116
I +N + L P + K GLCG + + +DF R +V + W
Sbjct: 1425 GIIVIWDKNTRLSVILDPN-WNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKT 1483
Query: 2117 QRP-----GQTCQPILEEQCLVPDSSHCQVLLLPLFAECHKVLAPATFYAICQQDSCHQE 2171
+ QT C C++L F +CH + P+ ++ +C +++C +
Sbjct: 1484 SQECSDTVAQTFPCDSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACD 1543
Query: 2172 Q------VCEVIASYAHLCRTNGVCVDWRTPDFCAMSCPPSLVYNHCEHGCPRHCDGNVS 2225
C +A YA C GVCV WR P+ C + C YN P C +
Sbjct: 1544 MEGKYLGFCTAVAMYAEACSAVGVCVSWRKPNLCPVYCD---YYN-----APGECRWHYE 1595
Query: 2226 SCGDHPSEGC 2235
CG ++ C
Sbjct: 1596 PCGTVTAKTC 1605
Score = 49.7 bits (117), Expect = 4e-05
Identities = 46/174 (26%), Positives = 64/174 (36%), Gaps = 20/174 (11%)
Query: 2138 HCQVLLLPLFAECHKVLAPATFYA-ICQQDSCH---QEQVCEVIASYAHLCRTNG--VCV 2191
HC ++ F +C KV A + Y IC + C + C+ + + LC ++G
Sbjct: 688 HCNKIIGTYFEKCGKVAALSNDYKMICIDEYCQTRDKTSTCDTYSELSRLCASDGPGTFE 747
Query: 2192 DWRTPD--FCAMS-CPPSLVYNHCEHGCPRHCDGNVSSCGDHPSEGCFCPP----DKVML 2244
WR+ C CP +Y C P C GC CP D +
Sbjct: 748 SWRSDSDVVCGTQRCPEQHIYKECGPSNPATCSNVAPFQDSECVSGCTCPEGYLLDDIGE 807
Query: 2245 EGSCVPEEACTQCIGEDGVQHQFLEAWVPDHQPC-QICTCLSGRKVNCTTQPCP 2297
+G CV + C G +Q E PC CTC K +CT CP
Sbjct: 808 KGKCVLKAECP--CESSGTVYQPGEV---REGPCGSQCTC-QDAKWSCTEALCP 855
Score = 32.7 bits (73), Expect = 5.2
Identities = 18/65 (27%), Positives = 28/65 (43%), Gaps = 1/65 (1%)
Query: 386 GECLVTGQSHFKSFDNRYFTFSGICQYLLARDCQDHSFSIVIETVQCADDRDAVCTRSVT 445
GE + +KSF+ R F F C Y R C + IE ++ +DR +
Sbjct: 606 GEISTWSKGAYKSFNGRIFFFESSCPYTFCRHCIESGGDFNIE-IKRNNDRQDINEHIAN 664
Query: 446 VRLPG 450
++PG
Sbjct: 665 SKIPG 669
>gi|239757286 PREDICTED: similar to Fc fragment of IgG binding protein
[Homo sapiens]
Length = 1472
Score = 314 bits (805), Expect = 7e-85
Identities = 231/790 (29%), Positives = 325/790 (41%), Gaps = 90/790 (11%)
Query: 19 GTLCAEGTRGR----------SSTARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKR 68
G CA G R + STA C G TFDG Y G CSY + C +
Sbjct: 507 GMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSED 566
Query: 69 ----SFSIIGDFQNGKRVSLSVYLGEFFDIHLFVNG-TVTQGD--------QRVSMPYA- 114
+FS+ + +N R S V + + + ++T+G+ QR +P +
Sbjct: 567 DTLPAFSV--EAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSL 624
Query: 115 SKGLYLETEAGYYKLSGEAYGFVARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFM 174
S+G ++G + +G V D + L R+ ++ CGLCGN+N DDF+
Sbjct: 625 SEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFL 684
Query: 175 TQEGTLTSDPYDFANSWALSSGEQWCERASPPSS-SCNISSGEMQKGLWEQCQLLKSTSV 233
T +G L D +FA+SW L G+ CE + +C + +G L K
Sbjct: 685 TPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGP 744
Query: 234 FARCHPLVDPEPFVALCEKTLCECAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSP 293
FA CH +DP PF+ C LC G C L YA+ C + G+ + W + C
Sbjct: 745 FAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPL 804
Query: 294 VCPAGMEYRQCVSPCARTCQSLHINEMCQER-CVDGCSCPEGQLLDEGLCVESTECPCVH 352
CPA Y C C +C C R CV+GC C G + G CV ++ C C
Sbjct: 805 SCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCGCTF 864
Query: 353 SGKRYPPGTSLSRD--------CN----TCICRNSQWICSNEECP-------------GE 387
G + PG + D CN CR+ Q + E C G
Sbjct: 865 QGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGT 924
Query: 388 CLVTGQSHFKSFDNRYFTFSGICQYLLARDCQDH----SFSIVIETVQCADDRDAVCTRS 443
C +G H+ SFD R F F G C YLL C + +F +++E + + TR+
Sbjct: 925 CQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVEN-EHRGSQTVSYTRA 983
Query: 444 VTVRLPGLHNSLVKLKHGAGVAMDGQDVQLPLLKGDLRIQ---HTVTASVRLSYGEDLQM 500
V V G+ V+ ++ V +D LP D ++Q A VR +G +
Sbjct: 984 VRVEARGV-KVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTY 1042
Query: 501 DWDGRGRLLVKLSPVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWKLH---- 556
DW+ R+ K+ YA CGLCGN+NG+ DD G FGN+W+
Sbjct: 1043 DWN--ARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPG 1100
Query: 557 ------GDCQDLQKQHSDPCALNPRMTRFSEEACAVLTSP--TFEACHRAVSPLPYLRNC 608
GDC L + S+ C +L P F CH + P +R+C
Sbjct: 1101 CGATEPGDCPKLDSLVAQQLQ--------SKNECGILADPKGPFRECHSKLDPQGAVRDC 1152
Query: 609 RYDVCSCSDGRECLCGALASYAAACAGRGVRV-AWREPGRCELNCPKGQVYLQCGTPCNL 667
YD C LC ALA+YAAAC G V WR C L+CP Y C C L
Sbjct: 1153 VYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPL 1212
Query: 668 TCRSLSYPDEECNEACLEGCFCPPGLYMDERGDCVPKAQCPCYYDGEIFQPEDIF---SD 724
+C L P C C EGC C G + C+P A C C + G P F
Sbjct: 1213 SCGDLPVPG-GCGSECHEGCVCDEGFALSGE-SCLPLASCGCVHQGTYHPPGQTFYPGPG 1270
Query: 725 HHTMCYCEDG 734
++C+C++G
Sbjct: 1271 CDSLCHCQEG 1280
Score = 178 bits (451), Expect = 8e-44
Identities = 151/530 (28%), Positives = 218/530 (41%), Gaps = 83/530 (15%)
Query: 769 PPMVKLVCPADNLRAE--GLECTKTCQNYDL--ECMSMGCVSGCLCPPGMVRHENRCVAL 824
P L CPA N R E G C +C C CV GC+C PG V CV
Sbjct: 799 PANCPLSCPA-NSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPA 857
Query: 825 ERCPCFHQGKEYAPGETV--------KIGCNTCV----CRDRKWNCTDHVCDA------- 865
C C QG + APG+ V + CN CRD++ C
Sbjct: 858 SSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGC 917
Query: 866 ------TCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPG--TFRILVGNKGCSHP 917
TC G HY++FDG ++ F G C Y+LV CG N FR+LV N+
Sbjct: 918 YPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGS-CGQNAALPAFRVLVENEHRGSQ 976
Query: 918 SVKCKKRVTILVEGGEIEL---FDGEVNVKRPMK------DETHFEVVESGRYIILLLGK 968
+V + V + G ++ + + G+V V ++ + +V GR ++
Sbjct: 977 TVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDF 1036
Query: 969 ALSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKVS 1028
L+V +D + ++ + +Y E +CGLCGNF+G +DL + + FGNSW+
Sbjct: 1037 GLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQ-- 1094
Query: 1029 SQCADTRKVPLDSSPATC---HNNIMKQTMVDSSCRILT--SDVFQDCNKLVDPEPYLDV 1083
+TR + P C + + +Q + C IL F++C+ +DP+ +
Sbjct: 1095 ---EETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRD 1151
Query: 1084 CIYDTCSCESIGDCACFCDTIAAYAHVCAQHGKVV-TWRTATLCPQSCEERNLRENGYEC 1142
C+YD C G CD +A YA C G V WR+ LCP SC +
Sbjct: 1152 CVYDRCLLP--GQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHS-------- 1201
Query: 1143 EWRYNSCAPACQVTC-QHPEPLACPVQCVEGCHAHCPPGKILDELLQTCVDPEDCPVCEV 1201
Y +C+ C ++C P P C +C EGC C G L ++C+ C C
Sbjct: 1202 --HYEACSYGCPLSCGDLPVPGGCGSECHEGC--VCDEGFALSG--ESCLPLASCG-CVH 1254
Query: 1202 AGRRFASGKKVTLNPSDPEHCQICHCDVVNLTC---------EACQEPGG 1242
G G+ T P P +CHC L EACQ GG
Sbjct: 1255 QGTYHPPGQ--TFYPG-PGCDSLCHCQEGGLVSCESSSCGPHEACQPSGG 1301
Score = 157 bits (397), Expect = 1e-37
Identities = 127/477 (26%), Positives = 181/477 (37%), Gaps = 46/477 (9%)
Query: 35 CSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRS----FSIIGDFQNGKRVSLSVYL-- 88
C G +FDG + F G C+YLL G C + + F ++ +N R S +V
Sbjct: 925 CQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVL--VENEHRGSQTVSYTR 982
Query: 89 -------GEFFDIHLFVNGTVTQGDQRVSMPY-ASKGLYLETEAGYYKLSGEAYGFVARI 140
G + G V D +P+ A+ G G + +G
Sbjct: 983 AVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTY 1042
Query: 141 DGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGEQWC 200
D + + Y CGLCGNFN DD + G ++ F NSW + C
Sbjct: 1043 DWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEET-RPGC 1101
Query: 201 ERASPPSSSCNISSGEMQKGLWEQCQLLKSTS-VFARCHPLVDPEPFVALCEKTLCECAG 259
P S Q +C +L F CH +DP+ V C C G
Sbjct: 1102 GATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPG 1161
Query: 260 GLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCARTCQSLHINE 319
C AL YA C G ++ W C CP Y C C +C L +
Sbjct: 1162 QSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLPVPG 1221
Query: 320 MCQERCVDGCSCPEGQLLDEGLCVESTECPCVHSGKRYPPGTSL--SRDCNT-CICRNSQ 376
C C +GC C EG L C+ C CVH G +PPG + C++ C C+
Sbjct: 1222 GCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGG 1281
Query: 377 WI-CSNEEC-PGE------------------CLVTGQSHFKSFDNRYFTFSGICQYLLAR 416
+ C + C P E C +G H+ +FD R F F G C Y+LA+
Sbjct: 1282 LVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQ 1341
Query: 417 DCQD----HSFSIVIETVQCADDRDAVCTRSVTVRLPGLHNSLVKLKHGAGVAMDGQ 469
C H F+++ E V + R +V TR +TV++ L + + V DG+
Sbjct: 1342 TCGTRPGLHRFAVLQENVAWGNGRVSV-TRVITVQVANFTLRLEQRQWKVTVRADGE 1397
Score = 135 bits (340), Expect = 6e-31
Identities = 115/398 (28%), Positives = 169/398 (42%), Gaps = 43/398 (10%)
Query: 865 ATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPG--TFRILVGNKGCSHPSVKCK 922
A C G HY TFDG +Y G C Y +V+ C + F + N+ V
Sbjct: 531 AVCRAQGDPHYTTFDGRRYDMMGTCSYTMVE-LCSEDDTLPAFSVEAKNEHRGSRRVSYV 589
Query: 923 KRVTILVEGGEIELFDGEVNV--------KRPMK-DETHFEVVESGRYIILLLGKALSVV 973
VT+ + L GEV + P+ E V +SG ++ L L V
Sbjct: 590 GLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVVELVFGLVVT 649
Query: 974 WDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKVSS---Q 1030
+D +++ L +Q++VCGLCGN++G +D + + + D V+F +SWK+
Sbjct: 650 YDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYL 709
Query: 1031 CADTRKVPLDSSPATCHNNIMKQTMVDSSCRILT--SDVFQDCNKLVDPEPYLDVCIYDT 1088
C D + ++ PA C + D C +LT F C+ +DP P+L+ C+YD
Sbjct: 710 CEDGCQ---NNCPA-CTPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDL 765
Query: 1089 CSCESIGDCACFCDTIAAYAHVCAQHG-KVVTWRTATLCPQSCEERNLRENGYECEWRYN 1147
C G+ C ++AYA C + G V WR+ CP SC + RY
Sbjct: 766 CVVG--GERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSCPANS----------RYE 813
Query: 1148 SCAPACQVTCQ-HPEPLACPVQ-CVEGCHAHCPPGKILDELLQTCVDPEDCPVCEVAGRR 1205
C PAC +C P C + CVEGC C PG + CV C C G +
Sbjct: 814 LCGPACPTSCNGAAAPSNCSGRPCVEGC--VCLPGFVASG--GACVPASSCG-CTFQGLQ 868
Query: 1206 FASGKKVTLNPSDPEHCQICHCDVVNLTCEACQE-PGG 1242
A G++V + C C+ +TC Q P G
Sbjct: 869 LAPGQEVWADELCQRRC-TCNGATHQVTCRDKQSCPAG 905
Score = 129 bits (324), Expect = 4e-29
Identities = 117/440 (26%), Positives = 176/440 (40%), Gaps = 42/440 (9%)
Query: 1884 GNEKRPG-DVWTLPDQCHTVTCQPDGQTLLKSHRVNCDRGLRPSCPNSQSPVKVEETCGC 1942
G + PG +VW D+ C +G T H+V C + SCP + GC
Sbjct: 866 GLQLAPGQEVWA--DELCQRRCTCNGAT----HQVTCRD--KQSCPAGERCSVQNGLLGC 917
Query: 1943 RWTCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKEQDLEV----ILHNGACSPGAR 1998
C GS H V+FDG+ F G+C+Y+L + Q+ + +L
Sbjct: 918 YPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQT 977
Query: 1999 QGCMKSIEVKHSALSVELHSDM--EVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHLG 2056
+++ V+ + V + + +V V+ L +P+ + +V V+ V G
Sbjct: 978 VSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFG 1037
Query: 2057 HIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTV 2116
T T N P ++A GLCG + + A+D LR G + W
Sbjct: 1038 --LTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQE 1095
Query: 2117 Q-RPGQTCQPILEEQCLVPDS---------SHCQVLLLPL--FAECHKVLAPATFYAICQ 2164
+ RPG C C DS + C +L P F ECH L P C
Sbjct: 1096 ETRPG--CGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCV 1153
Query: 2165 QDSC----HQEQVCEVIASYAHLCRTNGVCVD-WRTPDFCAMSCPPSLVYNHCEHGCPRH 2219
D C +C+ +A+YA C+ G V WR+ + C +SCPP Y C +GCP
Sbjct: 1154 YDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLS 1213
Query: 2220 CDGNV---SSCGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWVPDHQ 2276
C G++ CG EGC C + SC+P +C C+ G H + + P
Sbjct: 1214 C-GDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASC-GCV-HQGTYHPPGQTFYPGPG 1270
Query: 2277 PCQICTCLSGRKVNCTTQPC 2296
+C C G V+C + C
Sbjct: 1271 CDSLCHCQEGGLVSCESSSC 1290
Score = 120 bits (302), Expect = 1e-26
Identities = 115/425 (27%), Positives = 170/425 (40%), Gaps = 44/425 (10%)
Query: 1908 GQTLLKSHRVNCDRGLRPSCPNSQSPVKVEETCGCRWTCPCVCTGSSTRHIVTFDGQNFK 1967
G+T+L +C+ G++ C Q V GC VC H TFDG+ +
Sbjct: 494 GRTVLSPVEPSCE-GMQ--CAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYD 550
Query: 1968 LTGSCSYVLFQNKEQDLEVIL--------HNGACSPGARQGCMKSIEVKHSALSVELHSD 2019
+ G+CSY + + +D + H G+ R + + V+ + SV L
Sbjct: 551 MMGTCSYTMVELCSEDDTLPAFSVEAKNEHRGS----RRVSYVGLVTVRAYSHSVSLTRG 606
Query: 2020 ME--VTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHLGHIFTFTPQNNEFQLQLS-PKT 2076
V V+ + +P + VY + V G + T+ + + QL LS P
Sbjct: 607 EVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVVELVFGLVVTY---DWDCQLALSLPAR 663
Query: 2077 FASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTVQRPGQTCQPILEEQCLVPDS 2136
F + GLCG + + A+DF+ DG + D W + C+ + C
Sbjct: 664 FQDQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTP 723
Query: 2137 SHCQV--------LLLPL---FAECHKVLAPATFYAICQQDSC----HQEQVCEVIASYA 2181
Q +L L FA CH L P F C D C + +C +++YA
Sbjct: 724 GQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYA 783
Query: 2182 HLCRTNGVCV-DWRTPDFCAMSCPPSLVYNHCEHGCPRHCDGNV--SSCGDHPS-EGCFC 2237
C G+ V DWR+P C +SCP + Y C CP C+G S+C P EGC C
Sbjct: 784 QACLELGISVGDWRSPANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVC 843
Query: 2238 PPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWVPDHQPCQICTCLSG-RKVNC-TTQP 2295
P V G+CVP +C C + E W D + CTC +V C Q
Sbjct: 844 LPGFVASGGACVPASSC-GCTFQGLQLAPGQEVWA-DELCQRRCTCNGATHQVTCRDKQS 901
Query: 2296 CPTAK 2300
CP +
Sbjct: 902 CPAGE 906
Score = 73.6 bits (179), Expect = 3e-12
Identities = 49/158 (31%), Positives = 68/158 (43%), Gaps = 26/158 (16%)
Query: 804 CVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAPGETVKIG--CNT-CVCRD------R 854
C GC+C G C+ L C C HQG + PG+T G C++ C C++
Sbjct: 1227 CHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCE 1286
Query: 855 KWNCTDH--------------VCDATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGS 900
+C H V +TC G HY TFDG ++ F G C YVL Q CG+
Sbjct: 1287 SSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQT-CGT 1345
Query: 901 NPG--TFRILVGNKGCSHPSVKCKKRVTILVEGGEIEL 936
PG F +L N + V + +T+ V + L
Sbjct: 1346 RPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRL 1383
Score = 40.8 bits (94), Expect = 0.019
Identities = 32/96 (33%), Positives = 37/96 (38%), Gaps = 25/96 (26%)
Query: 1900 HTVTCQPDGQTLLKS----HRVNCDRGLRPSCPNSQSPVKVEETCGCRWTCP-------C 1948
H T P GQT +C G SC +S +CG C C
Sbjct: 1254 HQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESS--------SCGPHEACQPSGGSLGC 1305
Query: 1949 VCTGSST------RHIVTFDGQNFKLTGSCSYVLFQ 1978
V GSST H TFDG+ F G+C YVL Q
Sbjct: 1306 VAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQ 1341
Score = 35.4 bits (80), Expect = 0.80
Identities = 34/121 (28%), Positives = 50/121 (41%), Gaps = 23/121 (19%)
Query: 2368 KRVSPPSCPPHRLPTLRKTQCCDEYECACNCVNSTVSCPLGYLASTATNDCGC------T 2421
+ + P SCPPH + C Y C +C + V G S C C +
Sbjct: 1190 EELCPLSCPPHS-----HYEACS-YGCPLSCGDLPVP---GGCGSECHEGCVCDEGFALS 1240
Query: 2422 TTTCLP--DKVCVHRSTIYPVGQ--FWEEGCD-VCTCTDMEDAVMGLRVAQCS-QKPCED 2475
+CLP CVH+ T +P GQ + GCD +C C E ++ + C + C+
Sbjct: 1241 GESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHC--QEGGLVSCESSSCGPHEACQP 1298
Query: 2476 S 2476
S
Sbjct: 1299 S 1299
Score = 32.7 bits (73), Expect = 5.2
Identities = 14/37 (37%), Positives = 18/37 (48%)
Query: 32 TARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKR 68
++ C G TFDG + F G C Y+LA C R
Sbjct: 1310 SSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTR 1346
>gi|239751787 PREDICTED: hypothetical protein XP_002348012 [Homo
sapiens]
Length = 3003
Score = 314 bits (805), Expect = 7e-85
Identities = 231/790 (29%), Positives = 325/790 (41%), Gaps = 90/790 (11%)
Query: 19 GTLCAEGTRGR----------SSTARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKR 68
G CA G R + STA C G TFDG Y G CSY + C +
Sbjct: 446 GMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSED 505
Query: 69 ----SFSIIGDFQNGKRVSLSVYLGEFFDIHLFVNG-TVTQGD--------QRVSMPYA- 114
+FS+ + +N R S V + + + ++T+G+ QR +P +
Sbjct: 506 DTLPAFSV--EAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSL 563
Query: 115 SKGLYLETEAGYYKLSGEAYGFVARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFM 174
S+G ++G + +G V D + L R+ ++ CGLCGN+N DDF+
Sbjct: 564 SEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFL 623
Query: 175 TQEGTLTSDPYDFANSWALSSGEQWCERASPPSS-SCNISSGEMQKGLWEQCQLLKSTSV 233
T +G L D +FA+SW L G+ CE + +C + +G L K
Sbjct: 624 TPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGP 683
Query: 234 FARCHPLVDPEPFVALCEKTLCECAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSP 293
FA CH +DP PF+ C LC G C L YA+ C + G+ + W + C
Sbjct: 684 FAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPL 743
Query: 294 VCPAGMEYRQCVSPCARTCQSLHINEMCQER-CVDGCSCPEGQLLDEGLCVESTECPCVH 352
CPA Y C C +C C R CV+GC C G + G CV ++ C C
Sbjct: 744 SCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCGCTF 803
Query: 353 SGKRYPPGTSLSRD--------CN----TCICRNSQWICSNEECP-------------GE 387
G + PG + D CN CR+ Q + E C G
Sbjct: 804 QGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGT 863
Query: 388 CLVTGQSHFKSFDNRYFTFSGICQYLLARDCQDH----SFSIVIETVQCADDRDAVCTRS 443
C +G H+ SFD R F F G C YLL C + +F +++E + + TR+
Sbjct: 864 CQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVEN-EHRGSQTVSYTRA 922
Query: 444 VTVRLPGLHNSLVKLKHGAGVAMDGQDVQLPLLKGDLRIQ---HTVTASVRLSYGEDLQM 500
V V G+ V+ ++ V +D LP D ++Q A VR +G +
Sbjct: 923 VRVEARGV-KVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTY 981
Query: 501 DWDGRGRLLVKLSPVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWKLH---- 556
DW+ R+ K+ YA CGLCGN+NG+ DD G FGN+W+
Sbjct: 982 DWN--ARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPG 1039
Query: 557 ------GDCQDLQKQHSDPCALNPRMTRFSEEACAVLTSP--TFEACHRAVSPLPYLRNC 608
GDC L + S+ C +L P F CH + P +R+C
Sbjct: 1040 CGATEPGDCPKLDSLVAQQLQ--------SKNECGILADPKGPFRECHSKLDPQGAVRDC 1091
Query: 609 RYDVCSCSDGRECLCGALASYAAACAGRGVRV-AWREPGRCELNCPKGQVYLQCGTPCNL 667
YD C LC ALA+YAAAC G V WR C L+CP Y C C L
Sbjct: 1092 VYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPL 1151
Query: 668 TCRSLSYPDEECNEACLEGCFCPPGLYMDERGDCVPKAQCPCYYDGEIFQPEDIF---SD 724
+C L P C C EGC C G + C+P A C C + G P F
Sbjct: 1152 SCGDLPVPG-GCGSECHEGCVCDEGFALSGE-SCLPLASCGCVHQGTYHPPGQTFYPGPG 1209
Query: 725 HHTMCYCEDG 734
++C+C++G
Sbjct: 1210 CDSLCHCQEG 1219
Score = 304 bits (779), Expect = 7e-82
Identities = 226/774 (29%), Positives = 313/774 (40%), Gaps = 89/774 (11%)
Query: 31 STARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQ-----KRSFSI-IGDFQNGKR--- 81
STA C +G T DG + F G C YLL+ C +F++ + + G +
Sbjct: 2070 STAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVS 2129
Query: 82 ----VSLSVY-----LGEFFDIHLFVNGTVTQGDQRVSMPYASKGLYLETEAGYYKLSGE 132
V+L +Y L + L V+G V++P+ L +G +
Sbjct: 2130 YTRSVTLQIYNHSLTLSARWPRKLQVDGVF------VALPFQLDSLLHAHLSGADVVVTT 2183
Query: 133 AYGFVARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWA 192
G DG ++ + Y CGLCGN+N DD G W
Sbjct: 2184 TSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAG--------WQ 2235
Query: 193 LSSGEQWCERASPPSSSCNISSGEMQKGLWEQCQLLKSTS-VFARCHPLVDPEPFVALCE 251
+ + E S P S + G + C ++ +T A CH LV P + C
Sbjct: 2236 VGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCL 2295
Query: 252 KTLCECAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCART 311
C+ G CPA+ Y C G L W C CPA Y C C +
Sbjct: 2296 LDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVS 2355
Query: 312 CQSLHINEMCQERCVDGCSCPEGQLLDEGLCVESTECPCVHSGKRYP------PGTSLSR 365
C SL E C+ C +GC C G +L CV +C C+H G+ YP PG R
Sbjct: 2356 CPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECER 2415
Query: 366 DCNT-----CICRNSQWICSNEECP-------------GECLVTGQSHFKSFDNRYFTFS 407
C C+ +EEC G CL G H+ + D R +
Sbjct: 2416 RCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLH 2475
Query: 408 GICQYLLARDCQ----DHSFSIVIETVQCADDRDAVCTRSVTVRLPGLHNSLVKLKHGAG 463
G C Y+LA+ C D FSIV+E D + + T + +V L G
Sbjct: 2476 GSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRLLVT---------VAGQVVSLAQGQQ 2526
Query: 464 VAMDGQDVQLPLLKGDLRIQHTVTASVR---LSYGEDLQMDWDGRGRLLVKLSPVYAGKT 520
V +DG+ V LP+ G +R VTA R L + L++ +DG LL+ + + G+
Sbjct: 2527 VTVDGEAVALPVAVGRVR----VTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRL 2582
Query: 521 CGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWKLHGDCQDLQK----QHSDPCALNPRM 576
CGLCGN+NGN DDF+ P+G A VE FG AW+ G + + Q C
Sbjct: 2583 CGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETA 2642
Query: 577 TRFSEEACAVLTSP--TFEACHRAVSPLPYLRNCRYDVCSCSDGRECLCGALASYAAACA 634
S EAC L +P F C +SP Y R C YD+C+ + LC +LA+Y AAC
Sbjct: 2643 PYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQ 2702
Query: 635 GRGVRV-AWREPGRCELNCPKGQVYLQCGTPCNLTCRSLSYPDEECNEACLEGCFCPPGL 693
GV V WR C L+CP Y C C +C +LS C C EGC C
Sbjct: 2703 AAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALS-GLTGCTTRCFEGCECDDRF 2761
Query: 694 YMDERGDCVPKAQCPCYYDGEIFQPED--IFSDHHTMCYCEDGF-MHCTMSGVP 744
+ + G C+P C C ++G + SD C C + C +G P
Sbjct: 2762 LLSQ-GVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCP 2814
Score = 293 bits (751), Expect = 1e-78
Identities = 227/802 (28%), Positives = 332/802 (41%), Gaps = 80/802 (9%)
Query: 35 CSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRS----FSIIGDFQNGKRVSLSVYL-- 88
C G +FDG + F G C+YLL G C + + F ++ +N R S +V
Sbjct: 864 CQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVL--VENEHRGSQTVSYTR 921
Query: 89 -------GEFFDIHLFVNGTVTQGDQRVSMPY-ASKGLYLETEAGYYKLSGEAYGFVARI 140
G + G V D +P+ A+ G G + +G
Sbjct: 922 AVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTY 981
Query: 141 DGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGEQWC 200
D + + Y CGLCGNFN DD + G ++ F NSW + C
Sbjct: 982 DWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEET-RPGC 1040
Query: 201 ERASPPSSSCNISSGEMQKGLWEQCQLLKSTS-VFARCHPLVDPEPFVALCEKTLCECAG 259
P S Q +C +L F CH +DP+ V C C G
Sbjct: 1041 GATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPG 1100
Query: 260 GLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCARTCQSLHINE 319
C AL YA C G ++ W C CP Y C C +C L +
Sbjct: 1101 QSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLPVPG 1160
Query: 320 MCQERCVDGCSCPEGQLLDEGLCVESTECPCVHSGKRYPPGTSL--SRDCNT-CICRNSQ 376
C C +GC C EG L C+ C CVH G +PPG + C++ C C+
Sbjct: 1161 GCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGG 1220
Query: 377 WI-CSNEEC-PGE------------------CLVTGQSHFKSFDNRYFTFSGICQYLLAR 416
+ C + C P E C +G H+ +FD R F F G C Y+LA+
Sbjct: 1221 LVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQ 1280
Query: 417 DCQD----HSFSIVIETVQCADDRDAVCTRSVTVRLPGLHNSLVKLKHGA-GVAMDGQDV 471
C H F+++ E V + R +V TR +TV++ N ++L+ V ++G D+
Sbjct: 1281 TCGTRPGLHRFAVLQENVAWGNGRVSV-TRVITVQVA---NFTLRLEQRQWKVTVNGVDM 1336
Query: 472 QLP--LLKGDLRI-QHTVTASVRLSYGEDLQMDWDGRGRLLVKLSPVYAGKTCGLCGNYN 528
+LP L G +R QH + +G L++ +D + V + Y + CGLCGNYN
Sbjct: 1337 KLPVVLANGQIRASQHGSDVVIETDFG--LRVAYDLVYYVRVTVPGNYYQQMCGLCGNYN 1394
Query: 529 GNQGDDFLTPSGLAEPRVEDFGNAWK-------------LHGDCQDLQKQHSDPCALNPR 575
G+ DDF P+G +FGN+W+ +D H P L +
Sbjct: 1395 GDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKK 1454
Query: 576 MTRFSEEACAVLTSPT--FEACHRAVSPLPYLRNCRYDVCSCSDGRECLCGALASYAAAC 633
+ EE C +L+SPT +CH+ V P L++C +D+C LC + +Y +AC
Sbjct: 1455 YQK--EEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSAC 1512
Query: 634 AGRGVRV-AWREPGRCELNCPKGQVYLQCGTPCNLTCRSLSYPDEECNEACLEGCFCPPG 692
G V WR C + CP Y C C+L C +LS P +C + C EGC C G
Sbjct: 1513 QAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAP-PQCQDGCAEGCQCDSG 1571
Query: 693 LYMDERGDCVPKAQCPCYYDGEIFQPED--IFSDHHTMCYCEDG-FMHC-TMSGVPGSLL 748
+ + CVP QC CY++G ++PE + + C C G M C S PG +
Sbjct: 1572 FLYNGQA-CVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEHSCKPGQVC 1630
Query: 749 -PDAVLSSPLSHRSKRSLSCRP 769
P + S ++ ++CRP
Sbjct: 1631 QPSGGILSCVTKDPCHGVTCRP 1652
Score = 280 bits (715), Expect = 2e-74
Identities = 222/777 (28%), Positives = 308/777 (39%), Gaps = 100/777 (12%)
Query: 33 ARCSLFGSDFVNTFDGSMYSFAGYCSYLLAG-GCQKRS------FSIIGDFQNGKR---- 81
A C L+G ++FDG + F G C+Y+LA GC S F++ QN
Sbjct: 1671 ATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVS 1730
Query: 82 -----------VSLSVYLGEFFDIHLFVNGTVTQ-----GDQRVSMPY-ASKGLYLETEA 124
++S++ E + + VNG +T D R+S+ ASK L +
Sbjct: 1731 YVRVVTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALLVAD-- 1788
Query: 125 GYYKLSGEAYGFVARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDP 184
+G D + V L Y CGLCGN + +D + GTL
Sbjct: 1789 ---------FGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSI 1839
Query: 185 YDFANSWALSSGEQWC-ERASPPSSSCNISSGEMQKGLWEQCQLLKSTS-VFARCHPLVD 242
+ SW + C + +C E +G L T F CH V
Sbjct: 1840 PIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLASGTGGPFTTCHAHVP 1899
Query: 243 PEPFVALCEKTLCECAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYR 302
PE F C +C G + C AL Y C G+V+ W C CP Y
Sbjct: 1900 PESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYE 1959
Query: 303 QCVSPCARTCQS---LHINEMCQERCVDGCSCPEGQLLDEGLCVE-STECPCVHSGKRYP 358
C PC +C S L +C+ CV+GC C G +L CV + C C +G +
Sbjct: 1960 VCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHE 2019
Query: 359 PGTSLSRDCNTCICRNSQW----------ICSNEEC--------------------PGEC 388
G+ D TC SQW +C+ C EC
Sbjct: 2020 AGSEFWAD-GTC----SQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAEC 2074
Query: 389 LVTGQSHFKSFDNRYFTFSGICQYLLARDCQDHSFSIVIETVQCADDR---DAVC-TRSV 444
G H+ + D F F G C+YLL+ C TV A++ AV TRSV
Sbjct: 2075 QAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSV 2134
Query: 445 TVRLPGLHNSLVKLKHGAGVAMDGQDVQLPLLKGDLRIQHTVTASVRLSYGEDLQMDWDG 504
T+++ H+ + + + +DG V LP L H A V ++ L + +DG
Sbjct: 2135 TLQIYN-HSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDG 2193
Query: 505 RGRLLVKLSPVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWKLHGDCQDLQK 564
+ +++ YA CGLCGNYN + DD G +P G A G+C + K
Sbjct: 2194 DSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGG--KPAGWQVGGAQGC-GEC--VSK 2248
Query: 565 QHSDPCALNPRMTRFSEEACAVL--TSPTFEACHRAVSPLPYLRNCRYDVCSCSDGRECL 622
PC + + +AC V+ T CH V P Y + C D C L
Sbjct: 2249 PCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGL 2308
Query: 623 CGALASYAAACAGRGVRVA-WREPGRCELNCPKGQVYLQCGTPCNLTCRSLSYPDEECNE 681
C A+A+Y AAC G ++ WR P C L CP Y CG C ++C SLS P E C
Sbjct: 2309 CPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAP-EGCES 2367
Query: 682 ACLEGCFCPPGLYMDERGD-CVPKAQCPCYYDGEIFQPEDIF---SDHHTMCYCEDG 734
AC EGC C G + GD CVP QC C +DG + ++F + C C G
Sbjct: 2368 ACREGCVCDAGFVLS--GDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPG 2422
Score = 269 bits (687), Expect = 3e-71
Identities = 226/794 (28%), Positives = 325/794 (40%), Gaps = 96/794 (12%)
Query: 32 TARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRS----FSIIGD---FQNGKRVSL 84
++ C G TFDG + F G C Y+LA C R F+++ + + NG+
Sbjct: 1249 SSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVT 1308
Query: 85 SVYLGEFFDIHLFVNG-----TVTQGDQRVSMPYASKGLYLETEAGYYKLSGEAYGFVAR 139
V + + L + TV D ++ + A+ G ++ G + +G
Sbjct: 1309 RVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLAN-GQIRASQHGSDVVIETDFGLRVA 1367
Query: 140 IDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGEQW 199
D +V + Y+ + CGLCGN+N +DDF G+ + +F NSW +
Sbjct: 1368 YDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSP 1427
Query: 200 C--ERASPPSSSCNISSG----EMQKGLWEQ--CQLLKS-TSVFARCHPLVDPEPFVALC 250
C PP S I S E++K ++ C LL S T + CH LVDP+ + C
Sbjct: 1428 CLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDC 1487
Query: 251 EKTLCECAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCAR 310
LC G L C + Y C G + W + C CP Y C C+
Sbjct: 1488 IFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSL 1547
Query: 311 TCQSLHINEMCQERCVDGCSCPEGQLLDEGLCVESTECPCVHSGKRY-PPGTSLSRDC-N 368
C +L CQ+ C +GC C G L + CV +C C H+G Y P T L +C
Sbjct: 1548 GCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQ 1607
Query: 369 TCICRNSQ-WICSNEEC-PGE--------------------------------------- 387
C C + +C C PG+
Sbjct: 1608 QCTCHAGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLP 1667
Query: 388 -----CLVTGQSHFKSFDNRYFTFSGICQYLLA-RDCQDHS------FSIVIETVQCADD 435
C + G H+ SFD R F F G C Y+LA C S F++ + Q +
Sbjct: 1668 NYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKN-QNRGN 1726
Query: 436 RDAVCTRSVTVRLPGLHNSLVKLKHG-AGVAMDGQDVQLPLLKGDLRIQHTVTASVRLSY 494
R VTV G + S+ K + G V ++G LP+ D RI AS L
Sbjct: 1727 PAVSYVRVVTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALLV 1786
Query: 495 GE-DLQMDWDGRGRLLVKLSPVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAW 553
+ LQ+ +D R+ V L Y G CGLCGN + N +D + P+G P + +G +W
Sbjct: 1787 ADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSW 1846
Query: 554 KLHG---DCQDLQKQHSDPCALNPRMTRFSEEA-CAVLTSPT---FEACHRAVSPLPYLR 606
+ G C D + + S P R+ ++ C L S T F CH V P + +
Sbjct: 1847 RAPGWDPLCWD-ECRGSCPTCPEDRLEQYEGPGFCGPLASGTGGPFTTCHAHVPPESFFK 1905
Query: 607 NCRYDVCSCSDGRECLCGALASYAAACAGRGVRVA-WREPGRCELNCPKGQVYLQCGTPC 665
C DVC R+ LC ALASY AAC GV + WR CE+ CP+ Y CG PC
Sbjct: 1906 GCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPC 1965
Query: 666 NLTCRS---LSYPDEECNEACLEGCFCPPGLYMDERGDCVP-KAQCPCYYDGEIFQP-ED 720
+C S L+ P C C+EGC C G + CVP C C+ +G + +
Sbjct: 1966 PASCPSPAPLTTP-AVCEGPCVEGCQCDAGFVL-SADRCVPLNNGCGCWANGTYHEAGSE 2023
Query: 721 IFSDHHTMCYCEDG 734
++D +C G
Sbjct: 2024 FWADGTCSQWCRCG 2037
Score = 178 bits (451), Expect = 8e-44
Identities = 151/530 (28%), Positives = 218/530 (41%), Gaps = 83/530 (15%)
Query: 769 PPMVKLVCPADNLRAE--GLECTKTCQNYDL--ECMSMGCVSGCLCPPGMVRHENRCVAL 824
P L CPA N R E G C +C C CV GC+C PG V CV
Sbjct: 738 PANCPLSCPA-NSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPA 796
Query: 825 ERCPCFHQGKEYAPGETV--------KIGCNTCV----CRDRKWNCTDHVCDA------- 865
C C QG + APG+ V + CN CRD++ C
Sbjct: 797 SSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGC 856
Query: 866 ------TCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPG--TFRILVGNKGCSHP 917
TC G HY++FDG ++ F G C Y+LV CG N FR+LV N+
Sbjct: 857 YPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGS-CGQNAALPAFRVLVENEHRGSQ 915
Query: 918 SVKCKKRVTILVEGGEIEL---FDGEVNVKRPMK------DETHFEVVESGRYIILLLGK 968
+V + V + G ++ + + G+V V ++ + +V GR ++
Sbjct: 916 TVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDF 975
Query: 969 ALSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKVS 1028
L+V +D + ++ + +Y E +CGLCGNF+G +DL + + FGNSW+
Sbjct: 976 GLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQ-- 1033
Query: 1029 SQCADTRKVPLDSSPATC---HNNIMKQTMVDSSCRILT--SDVFQDCNKLVDPEPYLDV 1083
+TR + P C + + +Q + C IL F++C+ +DP+ +
Sbjct: 1034 ---EETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRD 1090
Query: 1084 CIYDTCSCESIGDCACFCDTIAAYAHVCAQHGKVV-TWRTATLCPQSCEERNLRENGYEC 1142
C+YD C G CD +A YA C G V WR+ LCP SC +
Sbjct: 1091 CVYDRCLLP--GQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHS-------- 1140
Query: 1143 EWRYNSCAPACQVTC-QHPEPLACPVQCVEGCHAHCPPGKILDELLQTCVDPEDCPVCEV 1201
Y +C+ C ++C P P C +C EGC C G L ++C+ C C
Sbjct: 1141 --HYEACSYGCPLSCGDLPVPGGCGSECHEGC--VCDEGFALSG--ESCLPLASCG-CVH 1193
Query: 1202 AGRRFASGKKVTLNPSDPEHCQICHCDVVNLTC---------EACQEPGG 1242
G G+ T P P +CHC L EACQ GG
Sbjct: 1194 QGTYHPPGQ--TFYPG-PGCDSLCHCQEGGLVSCESSSCGPHEACQPSGG 1240
Score = 176 bits (447), Expect = 2e-43
Identities = 144/542 (26%), Positives = 216/542 (39%), Gaps = 53/542 (9%)
Query: 34 RCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKR----SFSII------GDFQNGKRVS 83
RC G T DG +Y G CSY+LA C + FSI+ GD Q
Sbjct: 2455 RCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQR----L 2510
Query: 84 LSVYLGEFFDIHLFVNGTVTQGDQRVSMPYASKGLYLETEAGYYKLSGEAYGFVARIDGS 143
L G+ + L VT + V++P A G T G + G DG
Sbjct: 2511 LVTVAGQV--VSLAQGQQVTVDGEAVALPVAV-GRVRVTAEGRNMVLQTTKGLRLLFDGD 2567
Query: 144 GNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGEQWCERA 203
+ + + + + CGLCGNFN DDF+ G+ S F +W + C
Sbjct: 2568 AHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEG 2627
Query: 204 SPPSSSCNISSGEMQKGLW--EQC-QLLKSTSVFARCHPLVDPEPFVALCEKTLCECAGG 260
P C + E E C QL FA C ++ P + C LC G
Sbjct: 2628 CGPQG-CPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGD 2686
Query: 261 LECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCARTCQSLHINEM 320
C +L Y C G+ + W S C CPA Y C C +C +L
Sbjct: 2687 KAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTG 2746
Query: 321 CQERCVDGCSCPEGQLLDEGLCVESTECPCVHSGKRYPPGTS-LSRDCN-TCICRNSQWI 378
C RC +GC C + LL +G+C+ +C C H+G+ P +S L+ DC+ C C +S +
Sbjct: 2747 CTTRCFEGCECDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGL 2806
Query: 379 -CSNEECP------------------GECLVTGQSHFKSFDNRYFTFSGICQYLLARDCQ 419
C CP G C+++ ++ +FD + Y L+ C
Sbjct: 2807 TCQAAGCPPGRVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGATTSPGVYELSSRCP 2866
Query: 420 DHS-----FSIVIETVQCADDRDAVCTRSVTVRLPGLHNSLVKLKHGAGVAMDGQDVQLP 474
+ +V E C +AV + + +V L GV ++G V LP
Sbjct: 2867 GLQNTIPWYRVVAEVQICHGKTEAVGQVHIF-----FQDGMVTLTPNKGVWVNGLRVDLP 2921
Query: 475 LLK-GDLRIQHTVTASVRLSYGEDLQMDWDGRGRLLVKLSPVYAGKTCGLCGNYNGNQGD 533
K + + T S+ + +Q+ G++ V +S +AGK CG CGN++G+Q +
Sbjct: 2922 AEKLASVSVSRTPDGSLLVRQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTN 2981
Query: 534 DF 535
D+
Sbjct: 2982 DW 2983
Score = 167 bits (423), Expect = 1e-40
Identities = 139/506 (27%), Positives = 202/506 (39%), Gaps = 75/506 (14%)
Query: 804 CVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAPGETVKIG--CNT-CVCRD------R 854
C GC+C G C+ L C C HQG + PG+T G C++ C C++
Sbjct: 1166 CHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCE 1225
Query: 855 KWNCTDH--------------VCDATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGS 900
+C H V +TC G HY TFDG ++ F G C YVL Q CG+
Sbjct: 1226 SSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQT-CGT 1284
Query: 901 NPGT--FRILVGNKGCSHPSVKCKKRVTILVEGGEIELFDGE-------VNVKRPMK-DE 950
PG F +L N + V + +T+ V + L + V++K P+
Sbjct: 1285 RPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLAN 1344
Query: 951 THFEVVESGRYIILLLGKALSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSS 1010
+ G +++ L V +D + V + Y +++CGLCGN++G +D
Sbjct: 1345 GQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKP 1404
Query: 1011 NLQVEEDPVDFGNSWK---VSSQCADTRKVPLDSSPA----TCHNNIMKQTMVDSSCRIL 1063
N + +FGNSW+ S C P S C + K+ + C +L
Sbjct: 1405 NGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLL 1464
Query: 1064 TSDV--FQDCNKLVDPEPYLDVCIYDTCSCESIGDCACFCDTIAAYAHVC-AQHGKVVTW 1120
+S C+KLVDP+ L CI+D C G+ + C I AY C A G V W
Sbjct: 1465 SSPTGPLSSCHKLVDPQGPLKDCIFDLCL--GGGNLSILCSNIHAYVSACQAAGGHVEPW 1522
Query: 1121 RTATLCPQSCEERNLRENGYECEWRYNSCAPACQVTCQHPEPLACPVQCVEGCHAHCPPG 1180
RT T CP C + Y CA C + C L+ P QC +GC C
Sbjct: 1523 RTETFCPMECPPNS----------HYELCADTCSLGC---SALSAPPQCQDGCAEGCQCD 1569
Query: 1181 KILDELLQTCVDPEDCPVCEVAGRRFASGKKVTLNPSDPEHC-QICHCDV-VNLTC---- 1234
Q CV + C C G + + V + ++C Q C C + C
Sbjct: 1570 SGFLYNGQACVPIQQCG-CYHNGVYYEPEQTVLI-----DNCRQQCTCHAGKGMVCQEHS 1623
Query: 1235 ----EACQEPGGLVVPPTDAPVSPTT 1256
+ CQ GG++ T P T
Sbjct: 1624 CKPGQVCQPSGGILSCVTKDPCHGVT 1649
Score = 157 bits (397), Expect = 1e-37
Identities = 160/643 (24%), Positives = 224/643 (34%), Gaps = 132/643 (20%)
Query: 683 CLEGCFCPPGLYMDERGDCVPKAQCPCYYD---------GEIFQPEDIFSDHHTMCYCED 733
CL CPPG DC+P +CP + G + P S H + +
Sbjct: 1428 CLPPTPCPPG-----SEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQG 1482
Query: 734 GFMHCTMSGVPGSLLPDAVLSSPLSHRSKRSLS---CRPPMVKLVCPADNLRAEGLE-CT 789
C G + S+ ++ S + P + CP + E C
Sbjct: 1483 PLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCA 1542
Query: 790 KTCQNYDLECMSM--------GCVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAPGET 841
TC L C ++ GC GC C G + + CV +++C C+H G Y P +T
Sbjct: 1543 DTCS---LGCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQT 1599
Query: 842 VKI-GCNT-CVCRDRKWN-CTDHVC----------------------------------- 863
V I C C C K C +H C
Sbjct: 1600 VLIDNCRQQCTCHAGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQ 1659
Query: 864 ----------DATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPGT-------FR 906
+ATC G HY +FDG K+ F G C YVL C PG F
Sbjct: 1660 GGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGC---PGVSTQGLTPFT 1716
Query: 907 ILVGNKGCSHPSVKCKKRVTILVEGGEIELFDGEVNVKRPMKD-----------ETHFEV 955
+ N+ +P+V + VT+ G I + E+ R + + V
Sbjct: 1717 VTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISV 1776
Query: 956 VESGRYIILLLGKALSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVE 1015
+ +L+ L V +D + + V L +Y VCGLCGN D NND N +
Sbjct: 1777 AQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLA 1836
Query: 1016 EDPVDFGNSWKV---SSQCADTRKVPLDSSPATCHNNIMKQTMVDSSCRILTSDV---FQ 1069
+G SW+ C D + S TC + ++Q C L S F
Sbjct: 1837 PSIPIWGGSWRAPGWDPLCWDECR----GSCPTCPEDRLEQYEGPGFCGPLASGTGGPFT 1892
Query: 1070 DCNKLVDPEPYLDVCIYDTCSCESIGDCACFCDTIAAYAHVCAQHGKVV-TWRTATLCPQ 1128
C+ V PE + C+ D C GD C +A+Y C G V+ WR C
Sbjct: 1893 TCHAHVPPESFFKGCVLDVCM--GGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEI 1950
Query: 1129 SCEERNLRENGYECEWRYNSCAPACQVTCQHPEPLACPV----QCVEGCHAHCPPGKILD 1184
+C E + Y C P C +C P PL P CVEGC C G +L
Sbjct: 1951 TCPENS----------HYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGC--QCDAGFVLS 1998
Query: 1185 ELLQTCVDPEDCPVCEVAGRRFASGKKVTLNPSDPEHCQICHC 1227
CV + C G +G + +D Q C C
Sbjct: 1999 --ADRCVPLNNGCGCWANGTYHEAGSEFW---ADGTCSQWCRC 2036
Score = 153 bits (386), Expect = 3e-36
Identities = 149/550 (27%), Positives = 210/550 (38%), Gaps = 73/550 (13%)
Query: 738 CTMSGVPGSLLPDAVLSSPLSHRSKRSLS--CRPPMVKLVCPA-DNLRAEGLECTKTCQN 794
C + G PG L P + L RP L CPA + G C +C +
Sbjct: 2299 CQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPS 2358
Query: 795 YDL-ECMSMGCVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAPGETVKIG--CNT-CV 850
E C GC+C G V + CV + +C C H G+ Y GE G C C
Sbjct: 2359 LSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCE 2418
Query: 851 CR-------DRKWNCTDH----------VCDAT----CSTIGMAHYLTFDGLKYLFPGEC 889
C C H C AT C G HY+T DG Y G C
Sbjct: 2419 CGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSC 2478
Query: 890 QYVLVQDYCGSNPGT--FRILVGNKGCSHPS---VKCKKRVTILVEGGEIELFDGEVNVK 944
YVL Q C PG F I++ V +V L +G ++ + DGE V
Sbjct: 2479 SYVLAQ-VCHPKPGDEDFSIVLEKNAAGDLQRLLVTVAGQVVSLAQGQQVTV-DGEA-VA 2535
Query: 945 RPMKDETHFEVVESGRYIILLLGKALSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQN 1004
P+ V GR ++L K L +++D + + + ++ ++CGLCGNF+G +
Sbjct: 2536 LPVA-VGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWS 2594
Query: 1005 NDLTSSNLQVEEDPVDFGNSWKV---SSQCADTRKVPLDSSPATCHNNIMKQTM---VDS 1058
+D N FG +W+ S C + P C + ++T +
Sbjct: 2595 DDFVLPNGSAASSVETFGAAWRAPGSSKGCGE------GCGPQGCPVCLAEETAPYESNE 2648
Query: 1059 SCRILTS--DVFQDCNKLVDPEPYLDVCIYDTCSCESIGDCACFCDTIAAYAHVCAQHGK 1116
+C L + F C ++ P Y C+YD C+ + GD A C ++AAY C G
Sbjct: 2649 ACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQK--GDKAFLCRSLAAYTAACQAAGV 2706
Query: 1117 VV-TWRTATLCPQSCEERNLRENGYECEWRYNSCAPACQVTCQHPEPL-ACPVQCVEGCH 1174
V WRT + CP C + Y+ C CQ +C L C +C EGC
Sbjct: 2707 AVKPWRTDSFCPLHCPAHS----------HYSICTRTCQGSCAALSGLTGCTTRCFEGC- 2755
Query: 1175 AHCPPGKILDELLQTCVDPEDCPVCEVAGRRFASGKKVTLNPSDPEHCQICHCDVVNLTC 1234
C +L + C+ +DC C GR + L E C LTC
Sbjct: 2756 -ECDDRFLLSQ--GVCIPVQDCG-CTHNGRYLPVNSSL-LTSDCSERCSCSSSS--GLTC 2808
Query: 1235 EACQEPGGLV 1244
+A P G V
Sbjct: 2809 QAAGCPPGRV 2818
Score = 135 bits (340), Expect = 6e-31
Identities = 115/398 (28%), Positives = 169/398 (42%), Gaps = 43/398 (10%)
Query: 865 ATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPG--TFRILVGNKGCSHPSVKCK 922
A C G HY TFDG +Y G C Y +V+ C + F + N+ V
Sbjct: 470 AVCRAQGDPHYTTFDGRRYDMMGTCSYTMVE-LCSEDDTLPAFSVEAKNEHRGSRRVSYV 528
Query: 923 KRVTILVEGGEIELFDGEVNV--------KRPMK-DETHFEVVESGRYIILLLGKALSVV 973
VT+ + L GEV + P+ E V +SG ++ L L V
Sbjct: 529 GLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVVELVFGLVVT 588
Query: 974 WDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKVSS---Q 1030
+D +++ L +Q++VCGLCGN++G +D + + + D V+F +SWK+
Sbjct: 589 YDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYL 648
Query: 1031 CADTRKVPLDSSPATCHNNIMKQTMVDSSCRILT--SDVFQDCNKLVDPEPYLDVCIYDT 1088
C D + ++ PA C + D C +LT F C+ +DP P+L+ C+YD
Sbjct: 649 CEDGCQ---NNCPA-CTPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDL 704
Query: 1089 CSCESIGDCACFCDTIAAYAHVCAQHG-KVVTWRTATLCPQSCEERNLRENGYECEWRYN 1147
C G+ C ++AYA C + G V WR+ CP SC + RY
Sbjct: 705 CVVG--GERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSCPANS----------RYE 752
Query: 1148 SCAPACQVTCQ-HPEPLACPVQ-CVEGCHAHCPPGKILDELLQTCVDPEDCPVCEVAGRR 1205
C PAC +C P C + CVEGC C PG + CV C C G +
Sbjct: 753 LCGPACPTSCNGAAAPSNCSGRPCVEGC--VCLPGFVASG--GACVPASSCG-CTFQGLQ 807
Query: 1206 FASGKKVTLNPSDPEHCQICHCDVVNLTCEACQE-PGG 1242
A G++V + C C+ +TC Q P G
Sbjct: 808 LAPGQEVWADELCQRRC-TCNGATHQVTCRDKQSCPAG 844
Score = 132 bits (332), Expect = 5e-30
Identities = 118/462 (25%), Positives = 184/462 (39%), Gaps = 60/462 (12%)
Query: 1883 DGNEKRPGDVWTLPDQCHT-VTCQPDGQTLLKSHRVNCDRGLRPSCPNSQSPVKVEETCG 1941
DG G+V+ +C C P G V C G +C + +
Sbjct: 2397 DGRYYPLGEVFYPGPECERRCECGPGGH-------VTCQEGA--ACGPHEECRLEDGVQA 2447
Query: 1942 CRWTCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQ-----NKEQDLEVILHNGACSPG 1996
C T C + H +T DG+ + L GSCSYVL Q ++D ++L A
Sbjct: 2448 CHATGCGRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAA--- 2504
Query: 1997 ARQGCMKSIEVKHSALSVELHSDMEVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHLG 2056
G ++ + V + V L +VTV+G V++P G + V G M L
Sbjct: 2505 ---GDLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLR 2561
Query: 2057 HIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEW-- 2114
+F + L P F + GLCG + N ++DF+L +G+ + +T W
Sbjct: 2562 LLF----DGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRA 2617
Query: 2115 --TVQRPGQTCQP------ILEEQCLVPDSSHCQVLLLPL--FAECHKVLAPATFYAICQ 2164
+ + G+ C P + EE + C L P FA C VL+P+ ++ C
Sbjct: 2618 PGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCV 2677
Query: 2165 QDSCHQEQ----VCEVIASYAHLCRTNGVCV-DWRTPDFCAMSCPPSLVYNHCEHGCPRH 2219
D C Q+ +C +A+Y C+ GV V WRT FC + CP Y+ C C
Sbjct: 2678 YDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGS 2737
Query: 2220 CD--GNVSSCGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQF----LEAWVP 2273
C ++ C EGC C ++ +G C+P + C G H + + +
Sbjct: 2738 CAALSGLTGCTTRCFEGCECDDRFLLSQGVCIPVQDC-------GCTHNGRYLPVNSSLL 2790
Query: 2274 DHQPCQICTCLSGRKVNCTTQPCPTAKAPTCGLCEVARLRQN 2315
+ C+C S + C CP + +CEV +N
Sbjct: 2791 TSDCSERCSCSSSSGLTCQAAGCPPGR-----VCEVKAEARN 2827
Score = 129 bits (324), Expect = 4e-29
Identities = 117/440 (26%), Positives = 176/440 (40%), Gaps = 42/440 (9%)
Query: 1884 GNEKRPG-DVWTLPDQCHTVTCQPDGQTLLKSHRVNCDRGLRPSCPNSQSPVKVEETCGC 1942
G + PG +VW D+ C +G T H+V C + SCP + GC
Sbjct: 805 GLQLAPGQEVWA--DELCQRRCTCNGAT----HQVTCRD--KQSCPAGERCSVQNGLLGC 856
Query: 1943 RWTCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKEQDLEV----ILHNGACSPGAR 1998
C GS H V+FDG+ F G+C+Y+L + Q+ + +L
Sbjct: 857 YPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQT 916
Query: 1999 QGCMKSIEVKHSALSVELHSDM--EVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHLG 2056
+++ V+ + V + + +V V+ L +P+ + +V V+ V G
Sbjct: 917 VSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFG 976
Query: 2057 HIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTV 2116
T T N P ++A GLCG + + A+D LR G + W
Sbjct: 977 --LTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQE 1034
Query: 2117 Q-RPGQTCQPILEEQCLVPDS---------SHCQVLLLPL--FAECHKVLAPATFYAICQ 2164
+ RPG C C DS + C +L P F ECH L P C
Sbjct: 1035 ETRPG--CGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCV 1092
Query: 2165 QDSC----HQEQVCEVIASYAHLCRTNGVCVD-WRTPDFCAMSCPPSLVYNHCEHGCPRH 2219
D C +C+ +A+YA C+ G V WR+ + C +SCPP Y C +GCP
Sbjct: 1093 YDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLS 1152
Query: 2220 CDGNV---SSCGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWVPDHQ 2276
C G++ CG EGC C + SC+P +C C+ G H + + P
Sbjct: 1153 C-GDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASC-GCV-HQGTYHPPGQTFYPGPG 1209
Query: 2277 PCQICTCLSGRKVNCTTQPC 2296
+C C G V+C + C
Sbjct: 1210 CDSLCHCQEGGLVSCESSSC 1229
Score = 120 bits (302), Expect = 1e-26
Identities = 115/425 (27%), Positives = 170/425 (40%), Gaps = 44/425 (10%)
Query: 1908 GQTLLKSHRVNCDRGLRPSCPNSQSPVKVEETCGCRWTCPCVCTGSSTRHIVTFDGQNFK 1967
G+T+L +C+ G++ C Q V GC VC H TFDG+ +
Sbjct: 433 GRTVLSPVEPSCE-GMQ--CAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYD 489
Query: 1968 LTGSCSYVLFQNKEQDLEVIL--------HNGACSPGARQGCMKSIEVKHSALSVELHSD 2019
+ G+CSY + + +D + H G+ R + + V+ + SV L
Sbjct: 490 MMGTCSYTMVELCSEDDTLPAFSVEAKNEHRGS----RRVSYVGLVTVRAYSHSVSLTRG 545
Query: 2020 ME--VTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHLGHIFTFTPQNNEFQLQLS-PKT 2076
V V+ + +P + VY + V G + T+ + + QL LS P
Sbjct: 546 EVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVVELVFGLVVTY---DWDCQLALSLPAR 602
Query: 2077 FASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTVQRPGQTCQPILEEQCLVPDS 2136
F + GLCG + + A+DF+ DG + D W + C+ + C
Sbjct: 603 FQDQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTP 662
Query: 2137 SHCQV--------LLLPL---FAECHKVLAPATFYAICQQDSC----HQEQVCEVIASYA 2181
Q +L L FA CH L P F C D C + +C +++YA
Sbjct: 663 GQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYA 722
Query: 2182 HLCRTNGVCV-DWRTPDFCAMSCPPSLVYNHCEHGCPRHCDGNV--SSCGDHPS-EGCFC 2237
C G+ V DWR+P C +SCP + Y C CP C+G S+C P EGC C
Sbjct: 723 QACLELGISVGDWRSPANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVC 782
Query: 2238 PPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWVPDHQPCQICTCLSG-RKVNC-TTQP 2295
P V G+CVP +C C + E W D + CTC +V C Q
Sbjct: 783 LPGFVASGGACVPASSC-GCTFQGLQLAPGQEVWA-DELCQRRCTCNGATHQVTCRDKQS 840
Query: 2296 CPTAK 2300
CP +
Sbjct: 841 CPAGE 845
Score = 115 bits (288), Expect = 6e-25
Identities = 124/500 (24%), Positives = 180/500 (36%), Gaps = 85/500 (17%)
Query: 767 CRPPMVKLVCPADNLRAEGLECTKTCQNYDLECMSMGCVSGCLCPPGMVRHENRCVALER 826
C PP CPA L C+ CV GC C G V +RCV L
Sbjct: 1961 CGPP-----CPASCPSPAPLTTPAVCEG--------PCVEGCQCDAGFVLSADRCVPLNN 2007
Query: 827 -CPC-----FHQ-GKEYAPGETVKIGCN------TCVCRDRKWNCTD---------HVCD 864
C C +H+ G E+ T C + VC + H C
Sbjct: 2008 GCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQ 2067
Query: 865 ----ATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPG--TFRILVGNKGCSHPS 918
A C G HY+T DG ++ F G C+Y+L G G F + V N+ +
Sbjct: 2068 PVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQA 2127
Query: 919 VKCKKRVTILVEGGEIEL---------FDGEVNVKRPMKDETHFEVVESGRYIILLLGKA 969
V + VT+ + + L DG V V P + ++ SG +++
Sbjct: 2128 VSYTRSVTLQIYNHSLTLSARWPRKLQVDG-VFVALPFQLDSLLHAHLSGADVVVTTTSG 2186
Query: 970 LSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKV-- 1027
LS+ +D + + + Y +CGLCGN++ +DL + V P W+V
Sbjct: 2187 LSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKA----VGGKPA----GWQVGG 2238
Query: 1028 SSQCADTRKVPLDSSPATCHNNIMKQTMVDSSCRIL--TSDVFQDCNKLVDPEPYLDVCI 1085
+ C + P P+ C + +C ++ T C+ LV P Y C+
Sbjct: 2239 AQGCGECVSKP---CPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCL 2295
Query: 1086 YDTCSCESIGDCACFCDTIAAYAHVCAQHG-KVVTWRTATLCPQSCEERNLRENGYECEW 1144
D C + G C +A Y C G ++ WR CP C +
Sbjct: 2296 LDACQVQ--GHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHS---------- 2343
Query: 1145 RYNSCAPACQVTCQH-PEPLACPVQCVEGCHAHCPPGKILDELLQTCVDPEDCPVCEVAG 1203
Y C +C V+C P C C EGC C G +L TCV C C G
Sbjct: 2344 HYELCGDSCPVSCPSLSAPEGCESACREGC--VCDAGFVLSG--DTCVPVGQCG-CLHDG 2398
Query: 1204 RRFASGKKVTLNPSDPEHCQ 1223
R + G+ P C+
Sbjct: 2399 RYYPLGEVFYPGPECERRCE 2418
Score = 108 bits (271), Expect = 6e-23
Identities = 101/405 (24%), Positives = 162/405 (40%), Gaps = 47/405 (11%)
Query: 1941 GCRWTCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQ-------NKEQDLEVILHNGAC 1993
GC+ C H VT DG F G+C Y+L E + +
Sbjct: 2065 GCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG 2124
Query: 1994 SPGARQGCMKSIEVKHSALSVELHSDMEVTVNGRLVSVPY-VGGNMEVNVYGAIMHEVRF 2052
S ++++ + +L++ ++ V+G V++P+ + + ++ GA +
Sbjct: 2125 SQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTT 2184
Query: 2053 NHLGHIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQ 2112
+ L F + F P +A+ GLCG +++ A+D G W+
Sbjct: 2185 SGLSLAF----DGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGK-PAGWQVGGA 2239
Query: 2113 EWT---VQRPGQT-CQPILEEQCLVPDSSHCQVLLL---PLFAECHKVLAPATFYAICQQ 2165
+ V +P + C P +E PD+ C V+ PL A CH ++ PA ++ C
Sbjct: 2240 QGCGECVSKPCPSPCTPEQQESFGGPDA--CGVISATDGPL-APCHGLVPPAQYFQGCLL 2296
Query: 2166 DSC----HQEQVCEVIASYAHLCRTNGVCV-DWRTPDFCAMSCPPSLVYNHCEHGCPRHC 2220
D+C H +C +A+Y C+ G + +WR PDFC + CP Y C CP C
Sbjct: 2297 DACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSC 2356
Query: 2221 ------DGNVSSCGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWVPD 2274
+G S+C EGC C V+ +CVP C C+ DG + E + P
Sbjct: 2357 PSLSAPEGCESAC----REGCVCDAGFVLSGDTCVPVGQC-GCL-HDGRYYPLGEVFYPG 2410
Query: 2275 HQPCQICTCLSGRKVNCTTQPCPTAKAPTCGLCEVARLRQNADQC 2319
+ + C C G V C + CG E RL C
Sbjct: 2411 PECERRCECGPGGHVTC-------QEGAACGPHEECRLEDGVQAC 2448
Score = 105 bits (262), Expect = 6e-22
Identities = 127/503 (25%), Positives = 183/503 (36%), Gaps = 97/503 (19%)
Query: 1900 HTVTCQPDGQTLLKS----HRVNCDRGLRPSCPNSQSPVKVEETCGCRWTCP-------C 1948
H T P GQT +C G SC +S +CG C C
Sbjct: 1193 HQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESS--------SCGPHEACQPSGGSLGC 1244
Query: 1949 VCTGSST------RHIVTFDGQNFKLTGSCSYVLFQ--NKEQDLE--VILHNGACSPGAR 1998
V GSST H TFDG+ F G+C YVL Q L +L R
Sbjct: 1245 VAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGR 1304
Query: 1999 QGCMKSIEVKHSALSVELHS-DMEVTVNGRLVSVPYV--GGNMEVNVYGA-IMHEVRFN- 2053
+ I V+ + ++ L +VTVNG + +P V G + + +G+ ++ E F
Sbjct: 1305 VSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGL 1364
Query: 2054 ----HLGHIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKT 2109
L + T N +Q + GLCG + + +DF +G+ +
Sbjct: 1365 RVAYDLVYYVRVTVPGNYYQ----------QMCGLCGNYNGDPKDDFQKPNGSQAGNANE 1414
Query: 2110 LVQEWTVQRPGQTCQPIL-----EEQCL------------VPDSSHCQVLLLPL--FAEC 2150
W P C P E C+ C +L P + C
Sbjct: 1415 FGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSC 1474
Query: 2151 HKVLAPATFYAICQQDSC----HQEQVCEVIASYAHLCRTNGVCVD-WRTPDFCAMSCPP 2205
HK++ P C D C + +C I +Y C+ G V+ WRT FC M CPP
Sbjct: 1475 HKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPP 1534
Query: 2206 SLVYNHCEHGCPRHCDGNVS--SCGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDGV 2263
+ Y C C C + C D +EGC C + +CVP + C C +GV
Sbjct: 1535 NSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVPIQQC-GCY-HNGV 1592
Query: 2264 QHQFLEAWVPDHQPC-QICTCLSGRKVNCTTQPCP--------------TAKAP----TC 2304
++ + + D+ C Q CTC +G+ + C C K P TC
Sbjct: 1593 YYEPEQTVLIDN--CRQQCTCHAGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTC 1650
Query: 2305 GLCEVARLRQNADQCCPEYECVC 2327
E + + C P YE C
Sbjct: 1651 RPQETCKEQGGQGVCLPNYEATC 1673
Score = 91.3 bits (225), Expect = 1e-17
Identities = 114/470 (24%), Positives = 166/470 (35%), Gaps = 77/470 (16%)
Query: 1897 DQCHTVTCQPDGQTLLKSHRVNCDRGLRPSC-PNSQSPVKVEETCGCRWTCPCVCTGSST 1955
D CH VTC+P Q K ++G + C PN E TC W P
Sbjct: 1643 DPCHGVTCRP--QETCK------EQGGQGVCLPN------YEATCWL-WGDP-------- 1679
Query: 1956 RHIVTFDGQNFKLTGSCSYVLFQN-----KEQDLE--VILHNGACSPGARQGCMKSIEVK 2008
H +FDG+ F G+C+YVL Q L + ++ + V
Sbjct: 1680 -HYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVA 1738
Query: 2009 HSALSVELHSD----MEVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHLGHIFTFTPQ 2064
++ +H D + V VNG L ++P + ++V + G ++
Sbjct: 1739 ALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYD-W 1797
Query: 2065 NNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTVQRPGQTCQ 2124
N + L P ++ GLCG D N ND + +GT+ W C
Sbjct: 1798 NWRVDVTL-PSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCW 1856
Query: 2125 PILEEQCLVPDSSHCQVLLLP------------LFAECHKVLAPATFYAICQQDSC---- 2168
C + P F CH + P +F+ C D C
Sbjct: 1857 DECRGSCPTCPEDRLEQYEGPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVLDVCMGGG 1916
Query: 2169 HQEQVCEVIASYAHLCRTNGVCV-DWRTPDFCAMSCPPSLVYNHCEHGCPRHCDG----- 2222
++ +C+ +ASY C+ GV + DWR C ++CP + Y C CP C
Sbjct: 1917 DRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLT 1976
Query: 2223 NVSSCGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWVPDHQPCQICT 2282
+ C EGC C V+ CVP C +G H+ + D Q C
Sbjct: 1977 TPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGC-WANGTYHEAGSEFWADGTCSQWCR 2035
Query: 2283 C-LSGRKVNCTTQPCPTAKAPTCGLCEVARLRQNADQCCPEYECVCDPVS 2331
C G + CT +CGL EV L P + C PVS
Sbjct: 2036 CGPGGGSLVCT--------PASCGLGEVCGL-------LPSGQHGCQPVS 2070
Score = 56.2 bits (134), Expect = 4e-07
Identities = 103/444 (23%), Positives = 160/444 (36%), Gaps = 96/444 (21%)
Query: 618 GREC-LCG----------ALASYAAACAGRGVRVAWREPGRCELNCPKGQVYLQCGTPCN 666
GR C LCG L + +AA + AWR PG + C +G CG
Sbjct: 2580 GRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSK-GCGEG-----CGPQGC 2633
Query: 667 LTCRSLSYPDEECNEACLEGCFCPPGLYMDERGDCVPKAQCPCYYDGEIFQPEDIFSDH- 725
C + E NEAC G + +G P A C + P + F
Sbjct: 2634 PVCLAEETAPYESNEAC--------GQLRNPQG---PFATCQA-----VLSPSEYFRQCV 2677
Query: 726 HTMCYC--EDGFMHCTMSGVPGSLLPDAVLSSPLSHRSKRSLSCRPPMVKLVCPADNLRA 783
+ +C + F+ +++ + V P S L CPA + +
Sbjct: 2678 YDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDS---------FCPLHCPAHSHYS 2728
Query: 784 EGLECTKTCQNY-----DLECMSMGCVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAP 838
CT+TCQ L + C GC C + + C+ ++ C C H G+ Y P
Sbjct: 2729 I---CTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCIPVQDCGCTHNGR-YLP 2784
Query: 839 GETVKIGCNTCVCRDRKWNCTD--------------HVCDATC------STIGM------ 872
V T C +R +C+ VC+ +T G+
Sbjct: 2785 ---VNSSLLTSDCSER-CSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWATRGLCVLSVG 2840
Query: 873 AHYLTFDGLKYLFPGECQYVLVQDYCGSNPGT---FRILVGNKGCSHPSVKCKKRVTILV 929
A+ TFDG + Y L C T +R++ + C H + +V I
Sbjct: 2841 ANLTTFDGARGATTSPGVYEL-SSRCPGLQNTIPWYRVVAEVQIC-HGKTEAVGQVHIFF 2898
Query: 930 EGGEIELFDGE------VNVKRPMKDETHFEVVESGRYIILLLGKALSVVW-DRHLSISV 982
+ G + L + + V P + V + +L+ KA VW + ++V
Sbjct: 2899 QDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDGSLLVRQKAGVQVWLGANGKVAV 2958
Query: 983 VLKQTYQEKVCGLCGNFDGIQNND 1006
++ + K+CG CGNFDG Q ND
Sbjct: 2959 IVSNDHAGKLCGACGNFDGDQTND 2982
Score = 35.4 bits (80), Expect = 0.80
Identities = 34/121 (28%), Positives = 50/121 (41%), Gaps = 23/121 (19%)
Query: 2368 KRVSPPSCPPHRLPTLRKTQCCDEYECACNCVNSTVSCPLGYLASTATNDCGC------T 2421
+ + P SCPPH + C Y C +C + V G S C C +
Sbjct: 1129 EELCPLSCPPHS-----HYEACS-YGCPLSCGDLPVP---GGCGSECHEGCVCDEGFALS 1179
Query: 2422 TTTCLP--DKVCVHRSTIYPVGQ--FWEEGCD-VCTCTDMEDAVMGLRVAQCS-QKPCED 2475
+CLP CVH+ T +P GQ + GCD +C C E ++ + C + C+
Sbjct: 1180 GESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHC--QEGGLVSCESSSCGPHEACQP 1237
Query: 2476 S 2476
S
Sbjct: 1238 S 1238
Score = 34.7 bits (78), Expect = 1.4
Identities = 23/71 (32%), Positives = 33/71 (46%), Gaps = 13/71 (18%)
Query: 2557 CPSGFQLSCKTSACCPSCRCERMEACMLNGTVIGPGKTVMIDVC-TTCRCMVQVGVISGF 2615
C SGF + + AC P +C C NG P +TV+ID C C C G++
Sbjct: 1568 CDSGFLYNGQ--ACVPIQQC----GCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMV--- 1618
Query: 2616 KLECRKTTCNP 2626
C++ +C P
Sbjct: 1619 ---CQEHSCKP 1626
Score = 32.0 bits (71), Expect = 8.8
Identities = 49/178 (27%), Positives = 62/178 (34%), Gaps = 40/178 (22%)
Query: 2494 CLPSACEVVTGSPRG------DSQSSWKSVGSQ---WASPENPCLINECVRVKEEVFIQQ 2544
CL AC+V G P G ++ ++ G+Q W P+ C + E+
Sbjct: 2294 CLLDACQV-QGHPGGLCPAVATYVAACQAAGAQLGEWRRPDF-CPLQCPAHSHYELCGDS 2351
Query: 2545 RNVSCPQLEVP-----------VCPSGFQLSCKTSACCPSCRCERMEACMLNGTVIGPGK 2593
VSCP L P VC +GF LS T C C G V PG
Sbjct: 2352 CPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGP 2411
Query: 2594 TVMIDVCTTCRC------MVQVGVISGFKLECRKTTCNPCPLGYKEENNTGECCGRCL 2645
+ C C Q G G ECR G + + TG CGRCL
Sbjct: 2412 ----ECERRCECGPGGHVTCQEGAACGPHEECRLED------GVQACHATG--CGRCL 2457
>gi|154146262 Fc fragment of IgG binding protein [Homo sapiens]
Length = 5405
Score = 314 bits (805), Expect = 7e-85
Identities = 231/790 (29%), Positives = 325/790 (41%), Gaps = 90/790 (11%)
Query: 19 GTLCAEGTRGR----------SSTARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKR 68
G CA G R + STA C G TFDG Y G CSY + C +
Sbjct: 446 GMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSED 505
Query: 69 ----SFSIIGDFQNGKRVSLSVYLGEFFDIHLFVNG-TVTQGD--------QRVSMPYA- 114
+FS+ + +N R S V + + + ++T+G+ QR +P +
Sbjct: 506 DTLPAFSV--EAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSL 563
Query: 115 SKGLYLETEAGYYKLSGEAYGFVARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFM 174
S+G ++G + +G V D + L R+ ++ CGLCGN+N DDF+
Sbjct: 564 SEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFL 623
Query: 175 TQEGTLTSDPYDFANSWALSSGEQWCERASPPSS-SCNISSGEMQKGLWEQCQLLKSTSV 233
T +G L D +FA+SW L G+ CE + +C + +G L K
Sbjct: 624 TPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGP 683
Query: 234 FARCHPLVDPEPFVALCEKTLCECAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSP 293
FA CH +DP PF+ C LC G C L YA+ C + G+ + W + C
Sbjct: 684 FAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPL 743
Query: 294 VCPAGMEYRQCVSPCARTCQSLHINEMCQER-CVDGCSCPEGQLLDEGLCVESTECPCVH 352
CPA Y C C +C C R CV+GC C G + G CV ++ C C
Sbjct: 744 SCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCGCTF 803
Query: 353 SGKRYPPGTSLSRD--------CN----TCICRNSQWICSNEECP-------------GE 387
G + PG + D CN CR+ Q + E C G
Sbjct: 804 QGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGT 863
Query: 388 CLVTGQSHFKSFDNRYFTFSGICQYLLARDCQDH----SFSIVIETVQCADDRDAVCTRS 443
C +G H+ SFD R F F G C YLL C + +F +++E + + TR+
Sbjct: 864 CQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVEN-EHRGSQTVSYTRA 922
Query: 444 VTVRLPGLHNSLVKLKHGAGVAMDGQDVQLPLLKGDLRIQ---HTVTASVRLSYGEDLQM 500
V V G+ V+ ++ V +D LP D ++Q A VR +G +
Sbjct: 923 VRVEARGV-KVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTY 981
Query: 501 DWDGRGRLLVKLSPVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWKLH---- 556
DW+ R+ K+ YA CGLCGN+NG+ DD G FGN+W+
Sbjct: 982 DWN--ARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPG 1039
Query: 557 ------GDCQDLQKQHSDPCALNPRMTRFSEEACAVLTSP--TFEACHRAVSPLPYLRNC 608
GDC L + S+ C +L P F CH + P +R+C
Sbjct: 1040 CGATEPGDCPKLDSLVAQQLQ--------SKNECGILADPKGPFRECHSKLDPQGAVRDC 1091
Query: 609 RYDVCSCSDGRECLCGALASYAAACAGRGVRV-AWREPGRCELNCPKGQVYLQCGTPCNL 667
YD C LC ALA+YAAAC G V WR C L+CP Y C C L
Sbjct: 1092 VYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPL 1151
Query: 668 TCRSLSYPDEECNEACLEGCFCPPGLYMDERGDCVPKAQCPCYYDGEIFQPEDIF---SD 724
+C L P C C EGC C G + C+P A C C + G P F
Sbjct: 1152 SCGDLPVPG-GCGSECHEGCVCDEGFALSGE-SCLPLASCGCVHQGTYHPPGQTFYPGPG 1209
Query: 725 HHTMCYCEDG 734
++C+C++G
Sbjct: 1210 CDSLCHCQEG 1219
Score = 304 bits (779), Expect = 7e-82
Identities = 226/774 (29%), Positives = 313/774 (40%), Gaps = 89/774 (11%)
Query: 31 STARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQ-----KRSFSI-IGDFQNGKR--- 81
STA C +G T DG + F G C YLL+ C +F++ + + G +
Sbjct: 4470 STAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVS 4529
Query: 82 ----VSLSVY-----LGEFFDIHLFVNGTVTQGDQRVSMPYASKGLYLETEAGYYKLSGE 132
V+L +Y L + L V+G V++P+ L +G +
Sbjct: 4530 YTRSVTLQIYNHSLTLSARWPRKLQVDGVF------VALPFQLDSLLHAHLSGADVVVTT 4583
Query: 133 AYGFVARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWA 192
G DG ++ + Y CGLCGN+N DD G W
Sbjct: 4584 TSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAG--------WQ 4635
Query: 193 LSSGEQWCERASPPSSSCNISSGEMQKGLWEQCQLLKSTS-VFARCHPLVDPEPFVALCE 251
+ + E S P S + G + C ++ +T A CH LV P + C
Sbjct: 4636 VGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCL 4695
Query: 252 KTLCECAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCART 311
C+ G CPA+ Y C G L W C CPA Y C C +
Sbjct: 4696 LDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVS 4755
Query: 312 CQSLHINEMCQERCVDGCSCPEGQLLDEGLCVESTECPCVHSGKRYP------PGTSLSR 365
C SL E C+ C +GC C G +L CV +C C+H G+ YP PG R
Sbjct: 4756 CPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECER 4815
Query: 366 DCNT-----CICRNSQWICSNEECP-------------GECLVTGQSHFKSFDNRYFTFS 407
C C+ +EEC G CL G H+ + D R +
Sbjct: 4816 RCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLH 4875
Query: 408 GICQYLLARDCQ----DHSFSIVIETVQCADDRDAVCTRSVTVRLPGLHNSLVKLKHGAG 463
G C Y+LA+ C D FSIV+E D + + T + +V L G
Sbjct: 4876 GSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRLLVT---------VAGQVVSLAQGQQ 4926
Query: 464 VAMDGQDVQLPLLKGDLRIQHTVTASVR---LSYGEDLQMDWDGRGRLLVKLSPVYAGKT 520
V +DG+ V LP+ G +R VTA R L + L++ +DG LL+ + + G+
Sbjct: 4927 VTVDGEAVALPVAVGRVR----VTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRL 4982
Query: 521 CGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWKLHGDCQDLQK----QHSDPCALNPRM 576
CGLCGN+NGN DDF+ P+G A VE FG AW+ G + + Q C
Sbjct: 4983 CGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETA 5042
Query: 577 TRFSEEACAVLTSP--TFEACHRAVSPLPYLRNCRYDVCSCSDGRECLCGALASYAAACA 634
S EAC L +P F C +SP Y R C YD+C+ + LC +LA+Y AAC
Sbjct: 5043 PYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQ 5102
Query: 635 GRGVRV-AWREPGRCELNCPKGQVYLQCGTPCNLTCRSLSYPDEECNEACLEGCFCPPGL 693
GV V WR C L+CP Y C C +C +LS C C EGC C
Sbjct: 5103 AAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALS-GLTGCTTRCFEGCECDDRF 5161
Query: 694 YMDERGDCVPKAQCPCYYDGEIFQPED--IFSDHHTMCYCEDGF-MHCTMSGVP 744
+ + G C+P C C ++G + SD C C + C +G P
Sbjct: 5162 LLSQ-GVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCP 5214
Score = 293 bits (751), Expect = 1e-78
Identities = 227/802 (28%), Positives = 332/802 (41%), Gaps = 80/802 (9%)
Query: 35 CSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRS----FSIIGDFQNGKRVSLSVYL-- 88
C G +FDG + F G C+YLL G C + + F ++ +N R S +V
Sbjct: 864 CQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVL--VENEHRGSQTVSYTR 921
Query: 89 -------GEFFDIHLFVNGTVTQGDQRVSMPY-ASKGLYLETEAGYYKLSGEAYGFVARI 140
G + G V D +P+ A+ G G + +G
Sbjct: 922 AVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTY 981
Query: 141 DGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGEQWC 200
D + + Y CGLCGNFN DD + G ++ F NSW + C
Sbjct: 982 DWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEET-RPGC 1040
Query: 201 ERASPPSSSCNISSGEMQKGLWEQCQLLKSTS-VFARCHPLVDPEPFVALCEKTLCECAG 259
P S Q +C +L F CH +DP+ V C C G
Sbjct: 1041 GATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPG 1100
Query: 260 GLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCARTCQSLHINE 319
C AL YA C G ++ W C CP Y C C +C L +
Sbjct: 1101 QSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLPVPG 1160
Query: 320 MCQERCVDGCSCPEGQLLDEGLCVESTECPCVHSGKRYPPGTSL--SRDCNT-CICRNSQ 376
C C +GC C EG L C+ C CVH G +PPG + C++ C C+
Sbjct: 1161 GCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGG 1220
Query: 377 WI-CSNEEC-PGE------------------CLVTGQSHFKSFDNRYFTFSGICQYLLAR 416
+ C + C P E C +G H+ +FD R F F G C Y+LA+
Sbjct: 1221 LVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQ 1280
Query: 417 DCQD----HSFSIVIETVQCADDRDAVCTRSVTVRLPGLHNSLVKLKHGA-GVAMDGQDV 471
C H F+++ E V + R +V TR +TV++ N ++L+ V ++G D+
Sbjct: 1281 TCGTRPGLHRFAVLQENVAWGNGRVSV-TRVITVQVA---NFTLRLEQRQWKVTVNGVDM 1336
Query: 472 QLP--LLKGDLRI-QHTVTASVRLSYGEDLQMDWDGRGRLLVKLSPVYAGKTCGLCGNYN 528
+LP L G +R QH + +G L++ +D + V + Y + CGLCGNYN
Sbjct: 1337 KLPVVLANGQIRASQHGSDVVIETDFG--LRVAYDLVYYVRVTVPGNYYQQMCGLCGNYN 1394
Query: 529 GNQGDDFLTPSGLAEPRVEDFGNAWK-------------LHGDCQDLQKQHSDPCALNPR 575
G+ DDF P+G +FGN+W+ +D H P L +
Sbjct: 1395 GDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKK 1454
Query: 576 MTRFSEEACAVLTSPT--FEACHRAVSPLPYLRNCRYDVCSCSDGRECLCGALASYAAAC 633
+ EE C +L+SPT +CH+ V P L++C +D+C LC + +Y +AC
Sbjct: 1455 YQK--EEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSAC 1512
Query: 634 AGRGVRV-AWREPGRCELNCPKGQVYLQCGTPCNLTCRSLSYPDEECNEACLEGCFCPPG 692
G V WR C + CP Y C C+L C +LS P +C + C EGC C G
Sbjct: 1513 QAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAP-PQCQDGCAEGCQCDSG 1571
Query: 693 LYMDERGDCVPKAQCPCYYDGEIFQPED--IFSDHHTMCYCEDG-FMHC-TMSGVPGSLL 748
+ + CVP QC CY++G ++PE + + C C G M C S PG +
Sbjct: 1572 FLYNGQA-CVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEHSCKPGQVC 1630
Query: 749 -PDAVLSSPLSHRSKRSLSCRP 769
P + S ++ ++CRP
Sbjct: 1631 QPSGGILSCVTKDPCHGVTCRP 1652
Score = 288 bits (737), Expect = 5e-77
Identities = 227/808 (28%), Positives = 339/808 (41%), Gaps = 91/808 (11%)
Query: 31 STARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQ-----KRSFSI-IGDFQNGKR--- 81
STA C +G T DG ++F G C YLL+ C +F++ + + G +
Sbjct: 2068 STAECQAWGDPHYVTLDGHRFNFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVS 2127
Query: 82 ----VSLSVY-----LGEFFDIHLFVNGTVTQGDQRVSMPYASKGLYLETEAGYYKLSGE 132
V+L +Y L + L V+G V++P+ L +G +
Sbjct: 2128 YTRSVTLQIYNHSLTLSARWPRKLQVDGVF------VTLPFQLDSLLHAHLSGADVVVTT 2181
Query: 133 AYGFVARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWA 192
G DG ++ + Y CGLCGN+N DD G W
Sbjct: 2182 TSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPAG--------WQ 2233
Query: 193 LSSGEQWCERASPPSSSCNISSGEMQKGLWEQCQLLKSTS-VFARCHPLVDPEPFVALCE 251
+ + E S P S + G + C ++ +T A CH LV P + C
Sbjct: 2234 VGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCL 2293
Query: 252 KTLCECAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCART 311
C+ G CPA+ Y C G L W C CPA Y C C +
Sbjct: 2294 LDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGS 2353
Query: 312 CQSLHINEMCQERCVDGCSCPEGQLLDEGLCVESTECPCVHSGKRYPPGTSL--SRDCNT 369
C SL E C+ C +GC C G +L CV +C C+H + YP G + C++
Sbjct: 2354 CPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDS 2413
Query: 370 -CICRNSQWI-CSNEEC-PGE------------------CLVTGQSHFKSFDNRYFTFSG 408
C CR + C C P E C +G H+ +FD R F F G
Sbjct: 2414 LCRCREGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGRRFDFMG 2473
Query: 409 ICQYLLARDCQD----HSFSIVIETVQCADDRDAVCTRSVTVRLPGLHNSLVKLKHGA-G 463
C Y+LA+ C H F+++ E V + R +V TR +TV++ N ++L+
Sbjct: 2474 TCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSV-TRVITVQVA---NFTLRLEQRQWK 2529
Query: 464 VAMDGQDVQLP--LLKGDLRI-QHTVTASVRLSYGEDLQMDWDGRGRLLVKLSPVYAGKT 520
V ++G D++LP L G +R QH + +G L++ +D + V + Y
Sbjct: 2530 VTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFG--LRVAYDLVYYVRVTVPGNYYQLM 2587
Query: 521 CGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAW-KLHGDCQDLQKQ----------HSDP 569
CGLCGNYNG+ DDF P+G +FGN+W ++ D L S+
Sbjct: 2588 CGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSEGCIPSEE 2647
Query: 570 CALNPRMTRFSEEACAVLTSPT--FEACHRAVSPLPYLRNCRYDVCSCSDGRECLCGALA 627
C EE C +L+SPT +CH+ V P L++C +D+C LC +
Sbjct: 2648 CPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIH 2707
Query: 628 SYAAACAGRGVRV-AWREPGRCELNCPKGQVYLQCGTPCNLTCRSLSYPDEECNEACLEG 686
+Y +AC G +V WR C + CP+ Y C C+L C +LS P +C + C EG
Sbjct: 2708 AYVSACQAAGGQVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAP-LQCPDGCAEG 2766
Query: 687 CFCPPGLYMDERGDCVPKAQCPCYYDGEIFQPED--IFSDHHTMCYCEDGFMHCTM--SG 742
C C G + + CVP QC CY++G ++PE + + C C G + S
Sbjct: 2767 CQCDSGFLYNGQA-CVPIQQCGCYHNGAYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSC 2825
Query: 743 VPGSLL-PDAVLSSPLSHRSKRSLSCRP 769
PG + P + S ++ ++CRP
Sbjct: 2826 KPGQVCQPSGGILSCVNKDPCHGVTCRP 2853
Score = 286 bits (733), Expect = 2e-76
Identities = 227/808 (28%), Positives = 336/808 (41%), Gaps = 91/808 (11%)
Query: 31 STARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQ-----KRSFSI-IGDFQNGKR--- 81
STA C +G T DG + F G C YLL+ C +F++ + + G +
Sbjct: 3269 STAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVS 3328
Query: 82 ----VSLSVY-----LGEFFDIHLFVNGTVTQGDQRVSMPYASKGLYLETEAGYYKLSGE 132
V+L +Y L + L V+G V++P+ L +G +
Sbjct: 3329 YTRSVTLQIYNHSLTLSARWPRKLQVDGVF------VTLPFQLDSLLHAHLSGADVVVTT 3382
Query: 133 AYGFVARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWA 192
G DG ++ + Y CGLCGN+N DD G W
Sbjct: 3383 TSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPAG--------WQ 3434
Query: 193 LSSGEQWCERASPPSSSCNISSGEMQKGLWEQCQLLKSTS-VFARCHPLVDPEPFVALCE 251
+ + E S P S + G + C ++ +T A CH LV P + C
Sbjct: 3435 VGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCL 3494
Query: 252 KTLCECAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCART 311
C+ G CPA+ Y C G L W C CPA Y C C +
Sbjct: 3495 LDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGS 3554
Query: 312 CQSLHINEMCQERCVDGCSCPEGQLLDEGLCVESTECPCVHSGKRYPPGTSL--SRDCNT 369
C SL E C+ C +GC C G +L CV +C C+H + YP G + C++
Sbjct: 3555 CPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDS 3614
Query: 370 -CICRNSQWI-CSNEEC-PGE------------------CLVTGQSHFKSFDNRYFTFSG 408
C CR + C C P E C +G H+ +FD F F G
Sbjct: 3615 LCRCREGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGHRFDFMG 3674
Query: 409 ICQYLLARDCQD----HSFSIVIETVQCADDRDAVCTRSVTVRLPGLHNSLVKLKHGA-G 463
C Y+LA+ C H F+++ E V + R +V TR +TV++ N ++L+
Sbjct: 3675 TCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSV-TRVITVQVA---NFTLRLEQRQWK 3730
Query: 464 VAMDGQDVQLP--LLKGDLRI-QHTVTASVRLSYGEDLQMDWDGRGRLLVKLSPVYAGKT 520
V ++G D++LP L G +R QH + +G L++ +D + V + Y
Sbjct: 3731 VTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFG--LRVAYDLVYYVRVTVPGNYYQLM 3788
Query: 521 CGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAW-KLHGDCQDLQKQ----------HSDP 569
CGLCGNYNG+ DDF P+G +FGN+W ++ D L SD
Sbjct: 3789 CGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSAGCIPSDK 3848
Query: 570 CALNPRMTRFSEEACAVLTSPT--FEACHRAVSPLPYLRNCRYDVCSCSDGRECLCGALA 627
C EE C +L+SPT +CH+ V P L++C +D+C LC +
Sbjct: 3849 CPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIH 3908
Query: 628 SYAAACAGRGVRV-AWREPGRCELNCPKGQVYLQCGTPCNLTCRSLSYPDEECNEACLEG 686
+Y +AC G V WR C + CP+ Y C C+L C +LS P +C + C EG
Sbjct: 3909 AYVSACQAAGGHVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAP-LQCPDGCAEG 3967
Query: 687 CFCPPGLYMDERGDCVPKAQCPCYYDGEIFQPED--IFSDHHTMCYCEDGFMHCTM--SG 742
C C G + + CVP QC CY++G ++PE + + C C G + S
Sbjct: 3968 CQCDSGFLYNGQA-CVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSC 4026
Query: 743 VPGSLL-PDAVLSSPLSHRSKRSLSCRP 769
PG + P + S ++ ++CRP
Sbjct: 4027 KPGQVCQPSGGILSCVTKDPCHGVTCRP 4054
Score = 278 bits (711), Expect = 5e-74
Identities = 220/764 (28%), Positives = 302/764 (39%), Gaps = 76/764 (9%)
Query: 33 ARCSLFGSDFVNTFDGSMYSFAGYCSYLLAG-GCQKRS------FSIIGDFQNGKRVSLS 85
A C L+G ++FDG + F G C+Y+LA GC S F++ QN ++S
Sbjct: 4073 ATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVS 4132
Query: 86 VY-------LGEFFDIHLFVNGTVTQGDQRVSMPYASKGLYLETEAGYYK-LSGEAYGFV 137
LG IH G V ++P + + G K L +G
Sbjct: 4133 YVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQ 4192
Query: 138 ARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGE 197
D + V L Y CGLCGN + +D + GTL + SW +
Sbjct: 4193 VSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWD 4252
Query: 198 QWC-ERASPPSSSCNISSGEMQKGLWEQCQLLKSTS-VFARCHPLVDPEPFVALCEKTLC 255
C + +C E +G L T F CH V PE F C +C
Sbjct: 4253 PLCWDECRGSCPTCPEDRLEQYEGPGFCGPLSSGTGGPFTTCHAHVPPESFFKGCVLDVC 4312
Query: 256 ECAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCARTCQS- 314
G + C AL Y C G+V+ W C CP Y C PC +C S
Sbjct: 4313 MGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSP 4372
Query: 315 --LHINEMCQERCVDGCSCPEGQLLDEGLCVE-STECPCVHSGKRYPPGTSLSRDCNTCI 371
L +C+ CV+GC C G +L CV + C C +G + G+ D TC
Sbjct: 4373 APLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWAD-GTC- 4430
Query: 372 CRNSQW----------ICSNEEC--------------------PGECLVTGQSHFKSFDN 401
SQW +C+ C EC G H+ + D
Sbjct: 4431 ---SQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDG 4487
Query: 402 RYFTFSGICQYLLARDCQDHSFSIVIETVQCADDR---DAVC-TRSVTVRLPGLHNSLVK 457
F F G C+YLL+ C TV A++ AV TRSVT+++ H+ +
Sbjct: 4488 HRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYN-HSLTLS 4546
Query: 458 LKHGAGVAMDGQDVQLPLLKGDLRIQHTVTASVRLSYGEDLQMDWDGRGRLLVKLSPVYA 517
+ + +DG V LP L H A V ++ L + +DG + +++ YA
Sbjct: 4547 ARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYA 4606
Query: 518 GKTCGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWKLHGDCQDLQKQHSDPCALNPRMT 577
CGLCGNYN + DD G +P G A G+C + K PC + +
Sbjct: 4607 ASLCGLCGNYNQDPADDLKAVGG--KPAGWQVGGAQGC-GEC--VSKPCPSPCTPEQQES 4661
Query: 578 RFSEEACAVL--TSPTFEACHRAVSPLPYLRNCRYDVCSCSDGRECLCGALASYAAACAG 635
+AC V+ T CH V P Y + C D C LC A+A+Y AAC
Sbjct: 4662 FGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQA 4721
Query: 636 RGVRVA-WREPGRCELNCPKGQVYLQCGTPCNLTCRSLSYPDEECNEACLEGCFCPPGLY 694
G ++ WR P C L CP Y CG C ++C SLS P E C AC EGC C G
Sbjct: 4722 AGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAP-EGCESACREGCVCDAGFV 4780
Query: 695 MDERGD-CVPKAQCPCYYDGEIFQPEDIF---SDHHTMCYCEDG 734
+ GD CVP QC C +DG + ++F + C C G
Sbjct: 4781 LS--GDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPG 4822
Score = 278 bits (710), Expect = 7e-74
Identities = 222/767 (28%), Positives = 304/767 (39%), Gaps = 82/767 (10%)
Query: 33 ARCSLFGSDFVNTFDGSMYSFAGYCSYLLAG-GCQKRS------FSIIGDFQNGKRVSLS 85
A C L+G ++FDG + F G C+Y+LA GC S F++ QN ++S
Sbjct: 1671 ATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVS 1730
Query: 86 VY-------LGEFFDIHLFVNGTVTQGDQRVSMPYA-SKGLYLETEAGYYKLSGEAYGFV 137
LG IH G V ++P + + G T+ L +G
Sbjct: 1731 YVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQ 1790
Query: 138 ARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGE 197
D + V L Y CGLCGN + +D + GTL + SW +
Sbjct: 1791 VSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWD 1850
Query: 198 QWC-ERASPPSSSCNISSGEMQKGLWEQCQLLKSTS-VFARCHPLVDPEPFVALCEKTLC 255
C + +C E +G L T F CH V PE F C +C
Sbjct: 1851 PLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVC 1910
Query: 256 ECAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCARTCQS- 314
G + C AL Y C G+V+ W C CP Y C SPC +C S
Sbjct: 1911 MGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGSPCPASCPSP 1970
Query: 315 --LHINEMCQERCVDGCSCPEGQLLDEGLCVE-STECPCVHSGKRYPPGTSLSRDCNTCI 371
L +C+ CV+GC C G +L CV + C C +G + G+ D TC
Sbjct: 1971 APLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWAD-GTC- 2028
Query: 372 CRNSQW----------ICSNEEC--------------------PGECLVTGQSHFKSFDN 401
SQW +C+ C EC G H+ + D
Sbjct: 2029 ---SQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDG 2085
Query: 402 RYFTFSGICQYLLARDCQDHSFSIVIETVQCADDR---DAVC-TRSVTVRLPGLHNSLVK 457
F F G C+YLL+ C TV A++ AV TRSVT+++ H+ +
Sbjct: 2086 HRFNFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYN-HSLTLS 2144
Query: 458 LKHGAGVAMDGQDVQLPLLKGDLRIQHTVTASVRLSYGEDLQMDWDGRGRLLVKLSPVYA 517
+ + +DG V LP L H A V ++ L + +DG + +++ YA
Sbjct: 2145 ARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYA 2204
Query: 518 GKTCGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWKLHGDCQDLQKQHSDPCALNPRMT 577
G CGLCGNYN + DD G +P G A G+C + K PC + +
Sbjct: 2205 GSLCGLCGNYNQDPADDLKAVGG--KPAGWQVGGAQGC-GEC--VSKPCPSPCTPEQQES 2259
Query: 578 RFSEEACAVL--TSPTFEACHRAVSPLPYLRNCRYDVCSCSDGRECLCGALASYAAACAG 635
+AC V+ T CH V P Y + C D C LC A+A+Y AAC
Sbjct: 2260 FGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQA 2319
Query: 636 RGVRV-AWREPGRCELNCPKGQVYLQCGTPCNLTCRSLSYPDEECNEACLEGCFCPPGLY 694
G ++ WR P C CP Y CG C +C SLS P E C AC EGC C G
Sbjct: 2320 AGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAP-EGCESACREGCVCDAGFV 2378
Query: 695 MDERGD-CVPKAQCPCYYD------GEIFQPEDIFSDHHTMCYCEDG 734
+ GD CVP QC C +D G+ F P ++C C +G
Sbjct: 2379 LS--GDTCVPVGQCGCLHDDRYYPLGQTFYPG---PGCDSLCRCREG 2420
Score = 275 bits (704), Expect = 4e-73
Identities = 221/767 (28%), Positives = 303/767 (39%), Gaps = 82/767 (10%)
Query: 33 ARCSLFGSDFVNTFDGSMYSFAGYCSYLLAG-GCQKRS------FSIIGDFQNGKRVSLS 85
A C L+G ++FDG + F G C+Y+LA GC S F++ QN ++S
Sbjct: 2872 ATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVS 2931
Query: 86 VY-------LGEFFDIHLFVNGTVTQGDQRVSMPYA-SKGLYLETEAGYYKLSGEAYGFV 137
LG IH G V ++P + + G T+ L +G
Sbjct: 2932 YVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQ 2991
Query: 138 ARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGE 197
D + V L Y CGLCGN + +D + GTL + SW +
Sbjct: 2992 VSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWD 3051
Query: 198 QWC-ERASPPSSSCNISSGEMQKGLWEQCQLLKSTS-VFARCHPLVDPEPFVALCEKTLC 255
C + +C E +G L T F CH V PE F C +C
Sbjct: 3052 PLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVC 3111
Query: 256 ECAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCARTCQS- 314
G + C AL Y C G+V+ W C CP Y C PC +C S
Sbjct: 3112 MGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSP 3171
Query: 315 --LHINEMCQERCVDGCSCPEGQLLDEGLCVE-STECPCVHSGKRYPPGTSLSRDCNTCI 371
L +C+ CV+GC C G +L CV + C C +G + G+ D TC
Sbjct: 3172 APLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWAD-GTC- 3229
Query: 372 CRNSQW----------ICSNEEC--------------------PGECLVTGQSHFKSFDN 401
SQW +C+ C EC G H+ + D
Sbjct: 3230 ---SQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDG 3286
Query: 402 RYFTFSGICQYLLARDCQDHSFSIVIETVQCADDR---DAVC-TRSVTVRLPGLHNSLVK 457
F F G C+YLL+ C TV A++ AV TRSVT+++ H+ +
Sbjct: 3287 HRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYN-HSLTLS 3345
Query: 458 LKHGAGVAMDGQDVQLPLLKGDLRIQHTVTASVRLSYGEDLQMDWDGRGRLLVKLSPVYA 517
+ + +DG V LP L H A V ++ L + +DG + +++ YA
Sbjct: 3346 ARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYA 3405
Query: 518 GKTCGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWKLHGDCQDLQKQHSDPCALNPRMT 577
G CGLCGNYN + DD G +P G A G+C + K PC + +
Sbjct: 3406 GSLCGLCGNYNQDPADDLKAVGG--KPAGWQVGGAQGC-GEC--VSKPCPSPCTPEQQES 3460
Query: 578 RFSEEACAVL--TSPTFEACHRAVSPLPYLRNCRYDVCSCSDGRECLCGALASYAAACAG 635
+AC V+ T CH V P Y + C D C LC A+A+Y AAC
Sbjct: 3461 FGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQA 3520
Query: 636 RGVRV-AWREPGRCELNCPKGQVYLQCGTPCNLTCRSLSYPDEECNEACLEGCFCPPGLY 694
G ++ WR P C CP Y CG C +C SLS P E C AC EGC C G
Sbjct: 3521 AGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAP-EGCESACREGCVCDAGFV 3579
Query: 695 MDERGD-CVPKAQCPCYYD------GEIFQPEDIFSDHHTMCYCEDG 734
+ GD CVP QC C +D G+ F P ++C C +G
Sbjct: 3580 LS--GDTCVPVGQCGCLHDDRYYPLGQTFYPG---PGCDSLCRCREG 3621
Score = 270 bits (689), Expect = 2e-71
Identities = 226/793 (28%), Positives = 326/793 (41%), Gaps = 96/793 (12%)
Query: 32 TARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRS----FSIIGD---FQNGKRVSL 84
++ C G TFDG + F G C Y+LA C R F+++ + + NG+
Sbjct: 1249 SSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVT 1308
Query: 85 SVYLGEFFDIHLFVNG-----TVTQGDQRVSMPYASKGLYLETEAGYYKLSGEAYGFVAR 139
V + + L + TV D ++ + A+ G ++ G + +G
Sbjct: 1309 RVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLAN-GQIRASQHGSDVVIETDFGLRVA 1367
Query: 140 IDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGEQW 199
D +V + Y+ + CGLCGN+N +DDF G+ + +F NSW +
Sbjct: 1368 YDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSP 1427
Query: 200 C--ERASPPSSSCNISSG----EMQKGLWEQ--CQLLKS-TSVFARCHPLVDPEPFVALC 250
C PP S I S E++K ++ C LL S T + CH LVDP+ + C
Sbjct: 1428 CLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDC 1487
Query: 251 EKTLCECAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCAR 310
LC G L C + Y C G + W + C CP Y C C+
Sbjct: 1488 IFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSL 1547
Query: 311 TCQSLHINEMCQERCVDGCSCPEGQLLDEGLCVESTECPCVHSGKRY-PPGTSLSRDC-N 368
C +L CQ+ C +GC C G L + CV +C C H+G Y P T L +C
Sbjct: 1548 GCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQ 1607
Query: 369 TCICRNSQ-WICSNEEC-PGE--------------------------------------- 387
C C + +C C PG+
Sbjct: 1608 QCTCHAGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLP 1667
Query: 388 -----CLVTGQSHFKSFDNRYFTFSGICQYLLA-RDCQDHS------FSIVIETVQCADD 435
C + G H+ SFD R F F G C Y+LA C S F++ + Q +
Sbjct: 1668 NYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKN-QNRGN 1726
Query: 436 RDAVCTRSVTVRLPGLHNSLVKLKHGAGVAMDGQDVQLPLLKGDLRIQHTVTASVRLSYG 495
R VTV G + S+ K + G V ++G LP+ D RI T AS L
Sbjct: 1727 PAVSYVRVVTVAALGTNISIHKDEIGK-VRVNGVLTALPVSVADGRISVTQGASKALLVA 1785
Query: 496 E-DLQMDWDGRGRLLVKLSPVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWK 554
+ LQ+ +D R+ V L Y G CGLCGN + N +D + P+G P + +G +W+
Sbjct: 1786 DFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWR 1845
Query: 555 LHG---DCQDLQKQHSDPCALNPRMTRFSEEA-CAVL---TSPTFEACHRAVSPLPYLRN 607
G C D + + S P R+ ++ C L T F CH V P + +
Sbjct: 1846 APGWDPLCWD-ECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKG 1904
Query: 608 CRYDVCSCSDGRECLCGALASYAAACAGRGVRVA-WREPGRCELNCPKGQVYLQCGTPCN 666
C DVC R+ LC ALASY AAC GV + WR CE+ CP+ Y CG+PC
Sbjct: 1905 CVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGSPCP 1964
Query: 667 LTCRS---LSYPDEECNEACLEGCFCPPGLYMDERGDCVP-KAQCPCYYDGEIFQP-EDI 721
+C S L+ P C C+EGC C G + CVP C C+ +G + +
Sbjct: 1965 ASCPSPAPLTTP-AVCEGPCVEGCQCDAGFVL-SADRCVPLNNGCGCWANGTYHEAGSEF 2022
Query: 722 FSDHHTMCYCEDG 734
++D +C G
Sbjct: 2023 WADGTCSQWCRCG 2035
Score = 178 bits (451), Expect = 8e-44
Identities = 151/530 (28%), Positives = 218/530 (41%), Gaps = 83/530 (15%)
Query: 769 PPMVKLVCPADNLRAE--GLECTKTCQNYDL--ECMSMGCVSGCLCPPGMVRHENRCVAL 824
P L CPA N R E G C +C C CV GC+C PG V CV
Sbjct: 738 PANCPLSCPA-NSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPA 796
Query: 825 ERCPCFHQGKEYAPGETV--------KIGCNTCV----CRDRKWNCTDHVCDA------- 865
C C QG + APG+ V + CN CRD++ C
Sbjct: 797 SSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGC 856
Query: 866 ------TCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPG--TFRILVGNKGCSHP 917
TC G HY++FDG ++ F G C Y+LV CG N FR+LV N+
Sbjct: 857 YPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGS-CGQNAALPAFRVLVENEHRGSQ 915
Query: 918 SVKCKKRVTILVEGGEIEL---FDGEVNVKRPMK------DETHFEVVESGRYIILLLGK 968
+V + V + G ++ + + G+V V ++ + +V GR ++
Sbjct: 916 TVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDF 975
Query: 969 ALSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKVS 1028
L+V +D + ++ + +Y E +CGLCGNF+G +DL + + FGNSW+
Sbjct: 976 GLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQ-- 1033
Query: 1029 SQCADTRKVPLDSSPATC---HNNIMKQTMVDSSCRILT--SDVFQDCNKLVDPEPYLDV 1083
+TR + P C + + +Q + C IL F++C+ +DP+ +
Sbjct: 1034 ---EETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRD 1090
Query: 1084 CIYDTCSCESIGDCACFCDTIAAYAHVCAQHGKVV-TWRTATLCPQSCEERNLRENGYEC 1142
C+YD C G CD +A YA C G V WR+ LCP SC +
Sbjct: 1091 CVYDRCLLP--GQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHS-------- 1140
Query: 1143 EWRYNSCAPACQVTC-QHPEPLACPVQCVEGCHAHCPPGKILDELLQTCVDPEDCPVCEV 1201
Y +C+ C ++C P P C +C EGC C G L ++C+ C C
Sbjct: 1141 --HYEACSYGCPLSCGDLPVPGGCGSECHEGC--VCDEGFALSG--ESCLPLASCG-CVH 1193
Query: 1202 AGRRFASGKKVTLNPSDPEHCQICHCDVVNLTC---------EACQEPGG 1242
G G+ T P P +CHC L EACQ GG
Sbjct: 1194 QGTYHPPGQ--TFYPG-PGCDSLCHCQEGGLVSCESSSCGPHEACQPSGG 1240
Score = 177 bits (450), Expect = 1e-43
Identities = 154/565 (27%), Positives = 223/565 (39%), Gaps = 81/565 (14%)
Query: 738 CTMSGVPGSLLPDAVLSSPLSHRSKRSLS--CRPPMVKLVCPA-DNLRAEGLECTKTCQN 794
C + G PG L P + L RP CPA + G C +C +
Sbjct: 2297 CQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPS 2356
Query: 795 YDL-ECMSMGCVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAPGETVKIG--CNT-CV 850
E C GC+C G V + CV + +C C H + Y G+T G C++ C
Sbjct: 2357 LSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCR 2416
Query: 851 CRD------RKWNCTDH--------------VCDATCSTIGMAHYLTFDGLKYLFPGECQ 890
CR+ +C H V TC G HY TFDG ++ F G C
Sbjct: 2417 CREGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGRRFDFMGTCV 2476
Query: 891 YVLVQDYCGSNPGT--FRILVGNKGCSHPSVKCKKRVTILVEGGEIELFDGE-------V 941
YVL Q CG+ PG F +L N + V + +T+ V + L + V
Sbjct: 2477 YVLAQT-CGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGV 2535
Query: 942 NVKRPMK-DETHFEVVESGRYIILLLGKALSVVWDRHLSISVVLKQTYQEKVCGLCGNFD 1000
++K P+ + G +++ L V +D + V + Y + +CGLCGN++
Sbjct: 2536 DMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCGLCGNYN 2595
Query: 1001 GIQNNDLTSSNLQVEEDPVDFGNSWK---VSSQCADTRKVPLDSS----PATCHNNIMKQ 1053
G +D N + +FGNSW+ S C P S C + K+
Sbjct: 2596 GDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSEGCIPSEECPPELEKK 2655
Query: 1054 TMVDSSCRILTSDV--FQDCNKLVDPEPYLDVCIYDTCSCESIGDCACFCDTIAAYAHVC 1111
+ C +L+S C+KLVDP+ L CI+D C G+ + C I AY C
Sbjct: 2656 YQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCL--GGGNLSILCSNIHAYVSAC 2713
Query: 1112 -AQHGKVVTWRTATLCPQSCEERNLRENGYECEWRYNSCAPACQVTCQH-PEPLACPVQC 1169
A G+V WR T CP C + + Y CA C + C PL CP C
Sbjct: 2714 QAAGGQVEPWRNETFCPMECPQNS----------HYELCADTCSLGCSALSAPLQCPDGC 2763
Query: 1170 VEGCHAHCPPGKILDELLQTCVDPEDCPVCEVAGRRFASGKKVTLNPSDPEHC-QICHCD 1228
EGC C G + + Q CV + C C G + + V + ++C Q C C
Sbjct: 2764 AEGC--QCDSGFLYNG--QACVPIQQCG-CYHNGAYYEPEQTVLI-----DNCRQQCTCH 2813
Query: 1229 VVNLTC---------EACQEPGGLV 1244
V + + CQ GG++
Sbjct: 2814 VGKVVVCQEHSCKPGQVCQPSGGIL 2838
Score = 177 bits (449), Expect = 1e-43
Identities = 157/577 (27%), Positives = 226/577 (39%), Gaps = 81/577 (14%)
Query: 738 CTMSGVPGSLLPDAVLSSPLSHRSKRSLS--CRPPMVKLVCPA-DNLRAEGLECTKTCQN 794
C + G PG L P + L RP CPA + G C +C +
Sbjct: 3498 CQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPS 3557
Query: 795 YDL-ECMSMGCVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAPGETVKIG--CNT-CV 850
E C GC+C G V + CV + +C C H + Y G+T G C++ C
Sbjct: 3558 LSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCR 3617
Query: 851 CRD------RKWNCTDH--------------VCDATCSTIGMAHYLTFDGLKYLFPGECQ 890
CR+ +C H V TC G HY TFDG ++ F G C
Sbjct: 3618 CREGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGHRFDFMGTCV 3677
Query: 891 YVLVQDYCGSNPGT--FRILVGNKGCSHPSVKCKKRVTILVEGGEIELFDGE-------V 941
YVL Q CG+ PG F +L N + V + +T+ V + L + V
Sbjct: 3678 YVLAQT-CGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGV 3736
Query: 942 NVKRPMK-DETHFEVVESGRYIILLLGKALSVVWDRHLSISVVLKQTYQEKVCGLCGNFD 1000
++K P+ + G +++ L V +D + V + Y + +CGLCGN++
Sbjct: 3737 DMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCGLCGNYN 3796
Query: 1001 GIQNNDLTSSNLQVEEDPVDFGNSWK---VSSQCADTRKVPLDSSPA----TCHNNIMKQ 1053
G +D N + +FGNSW+ S C P S+ C + K+
Sbjct: 3797 GDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSAGCIPSDKCPPELEKK 3856
Query: 1054 TMVDSSCRILTSDV--FQDCNKLVDPEPYLDVCIYDTCSCESIGDCACFCDTIAAYAHVC 1111
+ C +L+S C+KLVDP+ L CI+D C G+ + C I AY C
Sbjct: 3857 YQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCL--GGGNLSILCSNIHAYVSAC 3914
Query: 1112 -AQHGKVVTWRTATLCPQSCEERNLRENGYECEWRYNSCAPACQVTCQH-PEPLACPVQC 1169
A G V WR T CP C + + Y CA C + C PL CP C
Sbjct: 3915 QAAGGHVEPWRNETFCPMECPQNS----------HYELCADTCSLGCSALSAPLQCPDGC 3964
Query: 1170 VEGCHAHCPPGKILDELLQTCVDPEDCPVCEVAGRRFASGKKVTLNPSDPEHC-QICHCD 1228
EGC C G + + Q CV + C C G + + V + ++C Q C C
Sbjct: 3965 AEGC--QCDSGFLYNG--QACVPIQQCG-CYHNGVYYEPEQTVLI-----DNCRQQCTCH 4014
Query: 1229 VVNLTC---------EACQEPGGLVVPPTDAPVSPTT 1256
V + + CQ GG++ T P T
Sbjct: 4015 VGKVVVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVT 4051
Score = 176 bits (447), Expect = 2e-43
Identities = 144/542 (26%), Positives = 216/542 (39%), Gaps = 53/542 (9%)
Query: 34 RCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKR----SFSII------GDFQNGKRVS 83
RC G T DG +Y G CSY+LA C + FSI+ GD Q
Sbjct: 4855 RCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQR----L 4910
Query: 84 LSVYLGEFFDIHLFVNGTVTQGDQRVSMPYASKGLYLETEAGYYKLSGEAYGFVARIDGS 143
L G+ + L VT + V++P A G T G + G DG
Sbjct: 4911 LVTVAGQV--VSLAQGQQVTVDGEAVALPVAV-GRVRVTAEGRNMVLQTTKGLRLLFDGD 4967
Query: 144 GNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGEQWCERA 203
+ + + + + CGLCGNFN DDF+ G+ S F +W + C
Sbjct: 4968 AHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEG 5027
Query: 204 SPPSSSCNISSGEMQKGLW--EQC-QLLKSTSVFARCHPLVDPEPFVALCEKTLCECAGG 260
P C + E E C QL FA C ++ P + C LC G
Sbjct: 5028 CGPQG-CPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGD 5086
Query: 261 LECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCARTCQSLHINEM 320
C +L Y C G+ + W S C CPA Y C C +C +L
Sbjct: 5087 KAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTG 5146
Query: 321 CQERCVDGCSCPEGQLLDEGLCVESTECPCVHSGKRYPPGTS-LSRDCN-TCICRNSQWI 378
C RC +GC C + LL +G+C+ +C C H+G+ P +S L+ DC+ C C +S +
Sbjct: 5147 CTTRCFEGCECDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGL 5206
Query: 379 -CSNEECP------------------GECLVTGQSHFKSFDNRYFTFSGICQYLLARDCQ 419
C CP G C+++ ++ +FD + Y L+ C
Sbjct: 5207 TCQAAGCPPGRVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGATTSPGVYELSSRCP 5266
Query: 420 DHS-----FSIVIETVQCADDRDAVCTRSVTVRLPGLHNSLVKLKHGAGVAMDGQDVQLP 474
+ +V E C +AV + + +V L GV ++G V LP
Sbjct: 5267 GLQNTIPWYRVVAEVQICHGKTEAVGQVHIF-----FQDGMVTLTPNKGVWVNGLRVDLP 5321
Query: 475 LLK-GDLRIQHTVTASVRLSYGEDLQMDWDGRGRLLVKLSPVYAGKTCGLCGNYNGNQGD 533
K + + T S+ + +Q+ G++ V +S +AGK CG CGN++G+Q +
Sbjct: 5322 AEKLASVSVSRTPDGSLLVRQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTN 5381
Query: 534 DF 535
D+
Sbjct: 5382 DW 5383
Score = 167 bits (423), Expect = 1e-40
Identities = 139/506 (27%), Positives = 202/506 (39%), Gaps = 75/506 (14%)
Query: 804 CVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAPGETVKIG--CNT-CVCRD------R 854
C GC+C G C+ L C C HQG + PG+T G C++ C C++
Sbjct: 1166 CHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCE 1225
Query: 855 KWNCTDH--------------VCDATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGS 900
+C H V +TC G HY TFDG ++ F G C YVL Q CG+
Sbjct: 1226 SSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQT-CGT 1284
Query: 901 NPGT--FRILVGNKGCSHPSVKCKKRVTILVEGGEIELFDGE-------VNVKRPMK-DE 950
PG F +L N + V + +T+ V + L + V++K P+
Sbjct: 1285 RPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLAN 1344
Query: 951 THFEVVESGRYIILLLGKALSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSS 1010
+ G +++ L V +D + V + Y +++CGLCGN++G +D
Sbjct: 1345 GQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKP 1404
Query: 1011 NLQVEEDPVDFGNSWK---VSSQCADTRKVPLDSSPA----TCHNNIMKQTMVDSSCRIL 1063
N + +FGNSW+ S C P S C + K+ + C +L
Sbjct: 1405 NGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLL 1464
Query: 1064 TSDV--FQDCNKLVDPEPYLDVCIYDTCSCESIGDCACFCDTIAAYAHVC-AQHGKVVTW 1120
+S C+KLVDP+ L CI+D C G+ + C I AY C A G V W
Sbjct: 1465 SSPTGPLSSCHKLVDPQGPLKDCIFDLCL--GGGNLSILCSNIHAYVSACQAAGGHVEPW 1522
Query: 1121 RTATLCPQSCEERNLRENGYECEWRYNSCAPACQVTCQHPEPLACPVQCVEGCHAHCPPG 1180
RT T CP C + Y CA C + C L+ P QC +GC C
Sbjct: 1523 RTETFCPMECPPNS----------HYELCADTCSLGC---SALSAPPQCQDGCAEGCQCD 1569
Query: 1181 KILDELLQTCVDPEDCPVCEVAGRRFASGKKVTLNPSDPEHC-QICHCDV-VNLTC---- 1234
Q CV + C C G + + V + ++C Q C C + C
Sbjct: 1570 SGFLYNGQACVPIQQCG-CYHNGVYYEPEQTVLI-----DNCRQQCTCHAGKGMVCQEHS 1623
Query: 1235 ----EACQEPGGLVVPPTDAPVSPTT 1256
+ CQ GG++ T P T
Sbjct: 1624 CKPGQVCQPSGGILSCVTKDPCHGVT 1649
Score = 155 bits (393), Expect = 4e-37
Identities = 160/639 (25%), Positives = 226/639 (35%), Gaps = 126/639 (19%)
Query: 683 CLEGCFCPPGLYMDERGDCVPKAQCPCYYD---------GEIFQPEDIFSDHHTMCYCED 733
CL CPPG C+P +CP + G + P S H + +
Sbjct: 3830 CLPPPTCPPG-----SAGCIPSDKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQG 3884
Query: 734 GFMHCTMSGVPGSLLPDAVLSSPLSHRSKRSLS---CRPPMVKLVCPADNLRAEGLE-CT 789
C G + S+ ++ S + P + CP + + E C
Sbjct: 3885 PLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRNETFCPMECPQNSHYELCA 3944
Query: 790 KTCQ------NYDLECMSMGCVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAPGETVK 843
TC + L+C GC GC C G + + CV +++C C+H G Y P +TV
Sbjct: 3945 DTCSLGCSALSAPLQCPD-GCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVL 4003
Query: 844 I-GCNT-CVCRDRKWN-CTDHVC------------------------------------- 863
I C C C K C +H C
Sbjct: 4004 IDNCRQQCTCHVGKVVVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGG 4063
Query: 864 --------DATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPGT-------FRIL 908
+ATC G HY +FDG K+ F G C YVL C PG F +
Sbjct: 4064 QGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGC---PGVSTQGLTPFTVT 4120
Query: 909 VGNKGCSHPSVKCKKRVTILVEGGEIELFDGEVNVKR--------PMK-DETHFEVVESG 959
N+ +P+V + VT+ G I + E+ R P+ + V +
Sbjct: 4121 TKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGA 4180
Query: 960 RYIILLLGKALSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPV 1019
+L+ L V +D + + V L +Y VCGLCGN D NND N +
Sbjct: 4181 SKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIP 4240
Query: 1020 DFGNSWKV---SSQCADTRKVPLDSSPATCHNNIMKQTMVDSSCRILTSDV---FQDCNK 1073
+G SW+ C D + S TC + ++Q C L+S F C+
Sbjct: 4241 IWGGSWRAPGWDPLCWDECR----GSCPTCPEDRLEQYEGPGFCGPLSSGTGGPFTTCHA 4296
Query: 1074 LVDPEPYLDVCIYDTCSCESIGDCACFCDTIAAYAHVCAQHGKVV-TWRTATLCPQSCEE 1132
V PE + C+ D C GD C +A+Y C G V+ WR C +C E
Sbjct: 4297 HVPPESFFKGCVLDVCM--GGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPE 4354
Query: 1133 RNLRENGYECEWRYNSCAPACQVTCQHPEPLACPV----QCVEGCHAHCPPGKILDELLQ 1188
+ Y C P C +C P PL P CVEGC C G +L
Sbjct: 4355 NS----------HYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGC--QCDAGFVLS--AD 4400
Query: 1189 TCVDPEDCPVCEVAGRRFASGKKVTLNPSDPEHCQICHC 1227
CV + C G +G + +D Q C C
Sbjct: 4401 RCVPLNNGCGCWANGTYHEAGSEFW---ADGTCSQWCRC 4436
Score = 155 bits (392), Expect = 5e-37
Identities = 160/639 (25%), Positives = 225/639 (35%), Gaps = 126/639 (19%)
Query: 683 CLEGCFCPPGLYMDERGDCVPKAQCPCYYD---------GEIFQPEDIFSDHHTMCYCED 733
CL CPPG C+P +CP + G + P S H + +
Sbjct: 2629 CLPPPTCPPG-----SEGCIPSEECPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQG 2683
Query: 734 GFMHCTMSGVPGSLLPDAVLSSPLSHRSKRSLS---CRPPMVKLVCPADNLRAEGLE-CT 789
C G + S+ ++ S + P + CP + + E C
Sbjct: 2684 PLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGQVEPWRNETFCPMECPQNSHYELCA 2743
Query: 790 KTCQ------NYDLECMSMGCVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAPGETVK 843
TC + L+C GC GC C G + + CV +++C C+H G Y P +TV
Sbjct: 2744 DTCSLGCSALSAPLQCPD-GCAEGCQCDSGFLYNGQACVPIQQCGCYHNGAYYEPEQTVL 2802
Query: 844 I-GCNT-CVCRDRKWN-CTDHVC------------------------------------- 863
I C C C K C +H C
Sbjct: 2803 IDNCRQQCTCHVGKVVVCQEHSCKPGQVCQPSGGILSCVNKDPCHGVTCRPQETCKEQGG 2862
Query: 864 --------DATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPGT-------FRIL 908
+ATC G HY +FDG K+ F G C YVL C PG F +
Sbjct: 2863 QGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGC---PGVSTQGLTPFTVT 2919
Query: 909 VGNKGCSHPSVKCKKRVTILVEGGEIELFDGEVNVKR--------PMK-DETHFEVVESG 959
N+ +P+V + VT+ G I + E+ R P+ + V +
Sbjct: 2920 TKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGA 2979
Query: 960 RYIILLLGKALSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPV 1019
+L+ L V +D + + V L +Y VCGLCGN D NND N +
Sbjct: 2980 SKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIP 3039
Query: 1020 DFGNSWKV---SSQCADTRKVPLDSSPATCHNNIMKQTMVDSSCRIL---TSDVFQDCNK 1073
+G SW+ C D + S TC + ++Q C L T F C+
Sbjct: 3040 IWGGSWRAPGWDPLCWDECR----GSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHA 3095
Query: 1074 LVDPEPYLDVCIYDTCSCESIGDCACFCDTIAAYAHVCAQHGKVV-TWRTATLCPQSCEE 1132
V PE + C+ D C GD C +A+Y C G V+ WR C +C E
Sbjct: 3096 HVPPESFFKGCVLDVCM--GGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPE 3153
Query: 1133 RNLRENGYECEWRYNSCAPACQVTCQHPEPLACPV----QCVEGCHAHCPPGKILDELLQ 1188
+ Y C P C +C P PL P CVEGC C G +L
Sbjct: 3154 NS----------HYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGC--QCDAGFVLS--AD 3199
Query: 1189 TCVDPEDCPVCEVAGRRFASGKKVTLNPSDPEHCQICHC 1227
CV + C G +G + +D Q C C
Sbjct: 3200 RCVPLNNGCGCWANGTYHEAGSEFW---ADGTCSQWCRC 3235
Score = 154 bits (389), Expect = 1e-36
Identities = 160/641 (24%), Positives = 224/641 (34%), Gaps = 130/641 (20%)
Query: 683 CLEGCFCPPGLYMDERGDCVPKAQCPCYYD---------GEIFQPEDIFSDHHTMCYCED 733
CL CPPG DC+P +CP + G + P S H + +
Sbjct: 1428 CLPPTPCPPG-----SEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQG 1482
Query: 734 GFMHCTMSGVPGSLLPDAVLSSPLSHRSKRSLS---CRPPMVKLVCPADNLRAEGLE-CT 789
C G + S+ ++ S + P + CP + E C
Sbjct: 1483 PLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCA 1542
Query: 790 KTCQNYDLECMSM--------GCVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAPGET 841
TC L C ++ GC GC C G + + CV +++C C+H G Y P +T
Sbjct: 1543 DTCS---LGCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQT 1599
Query: 842 VKI-GCNT-CVCRDRKWN-CTDHVC----------------------------------- 863
V I C C C K C +H C
Sbjct: 1600 VLIDNCRQQCTCHAGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQ 1659
Query: 864 ----------DATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPGT-------FR 906
+ATC G HY +FDG K+ F G C YVL C PG F
Sbjct: 1660 GGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGC---PGVSTQGLTPFT 1716
Query: 907 ILVGNKGCSHPSVKCKKRVTILVEGGEIELFDGEVNVKR--------PMK-DETHFEVVE 957
+ N+ +P+V + VT+ G I + E+ R P+ + V +
Sbjct: 1717 VTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQ 1776
Query: 958 SGRYIILLLGKALSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEED 1017
+L+ L V +D + + V L +Y VCGLCGN D NND N +
Sbjct: 1777 GASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPS 1836
Query: 1018 PVDFGNSWKV---SSQCADTRKVPLDSSPATCHNNIMKQTMVDSSCRIL---TSDVFQDC 1071
+G SW+ C D + S TC + ++Q C L T F C
Sbjct: 1837 IPIWGGSWRAPGWDPLCWDECR----GSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTC 1892
Query: 1072 NKLVDPEPYLDVCIYDTCSCESIGDCACFCDTIAAYAHVCAQHGKVV-TWRTATLCPQSC 1130
+ V PE + C+ D C GD C +A+Y C G V+ WR C +C
Sbjct: 1893 HAHVPPESFFKGCVLDVCM--GGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITC 1950
Query: 1131 EERNLRENGYECEWRYNSCAPACQVTCQHPEPLACPV----QCVEGCHAHCPPGKILDEL 1186
E + Y C C +C P PL P CVEGC C G +L
Sbjct: 1951 PENS----------HYEVCGSPCPASCPSPAPLTTPAVCEGPCVEGC--QCDAGFVLS-- 1996
Query: 1187 LQTCVDPEDCPVCEVAGRRFASGKKVTLNPSDPEHCQICHC 1227
CV + C G +G + +D Q C C
Sbjct: 1997 ADRCVPLNNGCGCWANGTYHEAGSEFW---ADGTCSQWCRC 2034
Score = 153 bits (386), Expect = 3e-36
Identities = 149/550 (27%), Positives = 210/550 (38%), Gaps = 73/550 (13%)
Query: 738 CTMSGVPGSLLPDAVLSSPLSHRSKRSLS--CRPPMVKLVCPA-DNLRAEGLECTKTCQN 794
C + G PG L P + L RP L CPA + G C +C +
Sbjct: 4699 CQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPS 4758
Query: 795 YDL-ECMSMGCVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAPGETVKIG--CNT-CV 850
E C GC+C G V + CV + +C C H G+ Y GE G C C
Sbjct: 4759 LSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCE 4818
Query: 851 CR-------DRKWNCTDH----------VCDAT----CSTIGMAHYLTFDGLKYLFPGEC 889
C C H C AT C G HY+T DG Y G C
Sbjct: 4819 CGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSC 4878
Query: 890 QYVLVQDYCGSNPGT--FRILVGNKGCSHPS---VKCKKRVTILVEGGEIELFDGEVNVK 944
YVL Q C PG F I++ V +V L +G ++ + DGE V
Sbjct: 4879 SYVLAQ-VCHPKPGDEDFSIVLEKNAAGDLQRLLVTVAGQVVSLAQGQQVTV-DGEA-VA 4935
Query: 945 RPMKDETHFEVVESGRYIILLLGKALSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQN 1004
P+ V GR ++L K L +++D + + + ++ ++CGLCGNF+G +
Sbjct: 4936 LPVA-VGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWS 4994
Query: 1005 NDLTSSNLQVEEDPVDFGNSWKV---SSQCADTRKVPLDSSPATCHNNIMKQTM---VDS 1058
+D N FG +W+ S C + P C + ++T +
Sbjct: 4995 DDFVLPNGSAASSVETFGAAWRAPGSSKGCGE------GCGPQGCPVCLAEETAPYESNE 5048
Query: 1059 SCRILTS--DVFQDCNKLVDPEPYLDVCIYDTCSCESIGDCACFCDTIAAYAHVCAQHGK 1116
+C L + F C ++ P Y C+YD C+ + GD A C ++AAY C G
Sbjct: 5049 ACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQK--GDKAFLCRSLAAYTAACQAAGV 5106
Query: 1117 VV-TWRTATLCPQSCEERNLRENGYECEWRYNSCAPACQVTCQHPEPL-ACPVQCVEGCH 1174
V WRT + CP C + Y+ C CQ +C L C +C EGC
Sbjct: 5107 AVKPWRTDSFCPLHCPAHS----------HYSICTRTCQGSCAALSGLTGCTTRCFEGC- 5155
Query: 1175 AHCPPGKILDELLQTCVDPEDCPVCEVAGRRFASGKKVTLNPSDPEHCQICHCDVVNLTC 1234
C +L + C+ +DC C GR + L E C LTC
Sbjct: 5156 -ECDDRFLLSQ--GVCIPVQDCG-CTHNGRYLPVNSSL-LTSDCSERCSCSSSS--GLTC 5208
Query: 1235 EACQEPGGLV 1244
+A P G V
Sbjct: 5209 QAAGCPPGRV 5218
Score = 135 bits (340), Expect = 6e-31
Identities = 115/398 (28%), Positives = 169/398 (42%), Gaps = 43/398 (10%)
Query: 865 ATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPG--TFRILVGNKGCSHPSVKCK 922
A C G HY TFDG +Y G C Y +V+ C + F + N+ V
Sbjct: 470 AVCRAQGDPHYTTFDGRRYDMMGTCSYTMVE-LCSEDDTLPAFSVEAKNEHRGSRRVSYV 528
Query: 923 KRVTILVEGGEIELFDGEVNV--------KRPMK-DETHFEVVESGRYIILLLGKALSVV 973
VT+ + L GEV + P+ E V +SG ++ L L V
Sbjct: 529 GLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVVELVFGLVVT 588
Query: 974 WDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKVSS---Q 1030
+D +++ L +Q++VCGLCGN++G +D + + + D V+F +SWK+
Sbjct: 589 YDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYL 648
Query: 1031 CADTRKVPLDSSPATCHNNIMKQTMVDSSCRILT--SDVFQDCNKLVDPEPYLDVCIYDT 1088
C D + ++ PA C + D C +LT F C+ +DP P+L+ C+YD
Sbjct: 649 CEDGCQ---NNCPA-CTPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDL 704
Query: 1089 CSCESIGDCACFCDTIAAYAHVCAQHG-KVVTWRTATLCPQSCEERNLRENGYECEWRYN 1147
C G+ C ++AYA C + G V WR+ CP SC + RY
Sbjct: 705 CVVG--GERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSCPANS----------RYE 752
Query: 1148 SCAPACQVTCQ-HPEPLACPVQ-CVEGCHAHCPPGKILDELLQTCVDPEDCPVCEVAGRR 1205
C PAC +C P C + CVEGC C PG + CV C C G +
Sbjct: 753 LCGPACPTSCNGAAAPSNCSGRPCVEGC--VCLPGFVASG--GACVPASSCG-CTFQGLQ 807
Query: 1206 FASGKKVTLNPSDPEHCQICHCDVVNLTCEACQE-PGG 1242
A G++V + C C+ +TC Q P G
Sbjct: 808 LAPGQEVWADELCQRRC-TCNGATHQVTCRDKQSCPAG 844
Score = 132 bits (332), Expect = 5e-30
Identities = 118/462 (25%), Positives = 184/462 (39%), Gaps = 60/462 (12%)
Query: 1883 DGNEKRPGDVWTLPDQCHT-VTCQPDGQTLLKSHRVNCDRGLRPSCPNSQSPVKVEETCG 1941
DG G+V+ +C C P G V C G +C + +
Sbjct: 4797 DGRYYPLGEVFYPGPECERRCECGPGGH-------VTCQEGA--ACGPHEECRLEDGVQA 4847
Query: 1942 CRWTCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQ-----NKEQDLEVILHNGACSPG 1996
C T C + H +T DG+ + L GSCSYVL Q ++D ++L A
Sbjct: 4848 CHATGCGRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAA--- 4904
Query: 1997 ARQGCMKSIEVKHSALSVELHSDMEVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHLG 2056
G ++ + V + V L +VTV+G V++P G + V G M L
Sbjct: 4905 ---GDLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLR 4961
Query: 2057 HIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEW-- 2114
+F + L P F + GLCG + N ++DF+L +G+ + +T W
Sbjct: 4962 LLF----DGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRA 5017
Query: 2115 --TVQRPGQTCQP------ILEEQCLVPDSSHCQVLLLPL--FAECHKVLAPATFYAICQ 2164
+ + G+ C P + EE + C L P FA C VL+P+ ++ C
Sbjct: 5018 PGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCV 5077
Query: 2165 QDSCHQEQ----VCEVIASYAHLCRTNGVCV-DWRTPDFCAMSCPPSLVYNHCEHGCPRH 2219
D C Q+ +C +A+Y C+ GV V WRT FC + CP Y+ C C
Sbjct: 5078 YDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGS 5137
Query: 2220 CD--GNVSSCGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQF----LEAWVP 2273
C ++ C EGC C ++ +G C+P + C G H + + +
Sbjct: 5138 CAALSGLTGCTTRCFEGCECDDRFLLSQGVCIPVQDC-------GCTHNGRYLPVNSSLL 5190
Query: 2274 DHQPCQICTCLSGRKVNCTTQPCPTAKAPTCGLCEVARLRQN 2315
+ C+C S + C CP + +CEV +N
Sbjct: 5191 TSDCSERCSCSSSSGLTCQAAGCPPGR-----VCEVKAEARN 5227
Score = 129 bits (324), Expect = 4e-29
Identities = 117/440 (26%), Positives = 176/440 (40%), Gaps = 42/440 (9%)
Query: 1884 GNEKRPG-DVWTLPDQCHTVTCQPDGQTLLKSHRVNCDRGLRPSCPNSQSPVKVEETCGC 1942
G + PG +VW D+ C +G T H+V C + SCP + GC
Sbjct: 805 GLQLAPGQEVWA--DELCQRRCTCNGAT----HQVTCRD--KQSCPAGERCSVQNGLLGC 856
Query: 1943 RWTCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKEQDLEV----ILHNGACSPGAR 1998
C GS H V+FDG+ F G+C+Y+L + Q+ + +L
Sbjct: 857 YPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQT 916
Query: 1999 QGCMKSIEVKHSALSVELHSDM--EVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHLG 2056
+++ V+ + V + + +V V+ L +P+ + +V V+ V G
Sbjct: 917 VSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFG 976
Query: 2057 HIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTV 2116
T T N P ++A GLCG + + A+D LR G + W
Sbjct: 977 --LTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQE 1034
Query: 2117 Q-RPGQTCQPILEEQCLVPDS---------SHCQVLLLPL--FAECHKVLAPATFYAICQ 2164
+ RPG C C DS + C +L P F ECH L P C
Sbjct: 1035 ETRPG--CGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCV 1092
Query: 2165 QDSC----HQEQVCEVIASYAHLCRTNGVCVD-WRTPDFCAMSCPPSLVYNHCEHGCPRH 2219
D C +C+ +A+YA C+ G V WR+ + C +SCPP Y C +GCP
Sbjct: 1093 YDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLS 1152
Query: 2220 CDGNV---SSCGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWVPDHQ 2276
C G++ CG EGC C + SC+P +C C+ G H + + P
Sbjct: 1153 C-GDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASC-GCV-HQGTYHPPGQTFYPGPG 1209
Query: 2277 PCQICTCLSGRKVNCTTQPC 2296
+C C G V+C + C
Sbjct: 1210 CDSLCHCQEGGLVSCESSSC 1229
Score = 120 bits (302), Expect = 1e-26
Identities = 115/425 (27%), Positives = 170/425 (40%), Gaps = 44/425 (10%)
Query: 1908 GQTLLKSHRVNCDRGLRPSCPNSQSPVKVEETCGCRWTCPCVCTGSSTRHIVTFDGQNFK 1967
G+T+L +C+ G++ C Q V GC VC H TFDG+ +
Sbjct: 433 GRTVLSPVEPSCE-GMQ--CAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYD 489
Query: 1968 LTGSCSYVLFQNKEQDLEVIL--------HNGACSPGARQGCMKSIEVKHSALSVELHSD 2019
+ G+CSY + + +D + H G+ R + + V+ + SV L
Sbjct: 490 MMGTCSYTMVELCSEDDTLPAFSVEAKNEHRGS----RRVSYVGLVTVRAYSHSVSLTRG 545
Query: 2020 ME--VTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHLGHIFTFTPQNNEFQLQLS-PKT 2076
V V+ + +P + VY + V G + T+ + + QL LS P
Sbjct: 546 EVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVVELVFGLVVTY---DWDCQLALSLPAR 602
Query: 2077 FASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTVQRPGQTCQPILEEQCLVPDS 2136
F + GLCG + + A+DF+ DG + D W + C+ + C
Sbjct: 603 FQDQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTP 662
Query: 2137 SHCQV--------LLLPL---FAECHKVLAPATFYAICQQDSC----HQEQVCEVIASYA 2181
Q +L L FA CH L P F C D C + +C +++YA
Sbjct: 663 GQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYA 722
Query: 2182 HLCRTNGVCV-DWRTPDFCAMSCPPSLVYNHCEHGCPRHCDGNV--SSCGDHPS-EGCFC 2237
C G+ V DWR+P C +SCP + Y C CP C+G S+C P EGC C
Sbjct: 723 QACLELGISVGDWRSPANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVC 782
Query: 2238 PPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWVPDHQPCQICTCLSG-RKVNC-TTQP 2295
P V G+CVP +C C + E W D + CTC +V C Q
Sbjct: 783 LPGFVASGGACVPASSC-GCTFQGLQLAPGQEVWA-DELCQRRCTCNGATHQVTCRDKQS 840
Query: 2296 CPTAK 2300
CP +
Sbjct: 841 CPAGE 845
Score = 115 bits (288), Expect = 6e-25
Identities = 124/500 (24%), Positives = 180/500 (36%), Gaps = 85/500 (17%)
Query: 767 CRPPMVKLVCPADNLRAEGLECTKTCQNYDLECMSMGCVSGCLCPPGMVRHENRCVALER 826
C PP CPA L C+ CV GC C G V +RCV L
Sbjct: 4361 CGPP-----CPASCPSPAPLTTPAVCEG--------PCVEGCQCDAGFVLSADRCVPLNN 4407
Query: 827 -CPC-----FHQ-GKEYAPGETVKIGCN------TCVCRDRKWNCTD---------HVCD 864
C C +H+ G E+ T C + VC + H C
Sbjct: 4408 GCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQ 4467
Query: 865 ----ATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPG--TFRILVGNKGCSHPS 918
A C G HY+T DG ++ F G C+Y+L G G F + V N+ +
Sbjct: 4468 PVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQA 4527
Query: 919 VKCKKRVTILVEGGEIEL---------FDGEVNVKRPMKDETHFEVVESGRYIILLLGKA 969
V + VT+ + + L DG V V P + ++ SG +++
Sbjct: 4528 VSYTRSVTLQIYNHSLTLSARWPRKLQVDG-VFVALPFQLDSLLHAHLSGADVVVTTTSG 4586
Query: 970 LSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKV-- 1027
LS+ +D + + + Y +CGLCGN++ +DL + V P W+V
Sbjct: 4587 LSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKA----VGGKPA----GWQVGG 4638
Query: 1028 SSQCADTRKVPLDSSPATCHNNIMKQTMVDSSCRIL--TSDVFQDCNKLVDPEPYLDVCI 1085
+ C + P P+ C + +C ++ T C+ LV P Y C+
Sbjct: 4639 AQGCGECVSKP---CPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCL 4695
Query: 1086 YDTCSCESIGDCACFCDTIAAYAHVCAQHG-KVVTWRTATLCPQSCEERNLRENGYECEW 1144
D C + G C +A Y C G ++ WR CP C +
Sbjct: 4696 LDACQVQ--GHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHS---------- 4743
Query: 1145 RYNSCAPACQVTCQH-PEPLACPVQCVEGCHAHCPPGKILDELLQTCVDPEDCPVCEVAG 1203
Y C +C V+C P C C EGC C G +L TCV C C G
Sbjct: 4744 HYELCGDSCPVSCPSLSAPEGCESACREGC--VCDAGFVLSG--DTCVPVGQCG-CLHDG 4798
Query: 1204 RRFASGKKVTLNPSDPEHCQ 1223
R + G+ P C+
Sbjct: 4799 RYYPLGEVFYPGPECERRCE 4818
Score = 108 bits (271), Expect = 6e-23
Identities = 130/528 (24%), Positives = 190/528 (35%), Gaps = 97/528 (18%)
Query: 767 CRPPMVKLVCPADNLRAEGLECTKTCQNYDLECMSMGCVSGCLCPPGMVRHENRCVALER 826
C PP CPA L C+ CV GC C G V +RCV L
Sbjct: 3160 CGPP-----CPASCPSPAPLTTPAVCEG--------PCVEGCQCDAGFVLSADRCVPLNN 3206
Query: 827 -CPC-----FHQ-GKEYAPGETVKIGCN------TCVCRDRKWNCTD---------HVCD 864
C C +H+ G E+ T C + VC + H C
Sbjct: 3207 GCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQ 3266
Query: 865 ----ATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPG--TFRILVGNKGCSHPS 918
A C G HY+T DG ++ F G C+Y+L G G F + V N+ +
Sbjct: 3267 PVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQA 3326
Query: 919 VKCKKRVTILVEGGEIEL---------FDGEVNVKRPMKDETHFEVVESGRYIILLLGKA 969
V + VT+ + + L DG V V P + ++ SG +++
Sbjct: 3327 VSYTRSVTLQIYNHSLTLSARWPRKLQVDG-VFVTLPFQLDSLLHAHLSGADVVVTTTSG 3385
Query: 970 LSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKV-- 1027
LS+ +D + + + Y +CGLCGN++ +DL + V P W+V
Sbjct: 3386 LSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKA----VGGKPA----GWQVGG 3437
Query: 1028 SSQCADTRKVPLDSSPATCHNNIMKQTMVDSSCRIL--TSDVFQDCNKLVDPEPYLDVCI 1085
+ C + P P+ C + +C ++ T C+ LV P Y C+
Sbjct: 3438 AQGCGECVSKP---CPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCL 3494
Query: 1086 YDTCSCESIGDCACFCDTIAAYAHVCAQHG-KVVTWRTATLCPQSCEERNLRENGYECEW 1144
D C + G C +A Y C G ++ WR CP C +
Sbjct: 3495 LDACQVQ--GHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHS---------- 3542
Query: 1145 RYNSCAPACQVTCQH-PEPLACPVQCVEGCHAHCPPGKILDELLQTCVDPEDCPVCEVAG 1203
Y C +C +C P C C EGC C G +L TCV C C
Sbjct: 3543 HYELCGDSCPGSCPSLSAPEGCESACREGC--VCDAGFVLSG--DTCVPVGQCG-CLHDD 3597
Query: 1204 RRFASGKKVTLNPSDPEHCQICHC-DVVNLTC--------EACQEPGG 1242
R + G+ T P P +C C + ++C E C+ GG
Sbjct: 3598 RYYPLGQ--TFYPG-PGCDSLCRCREGGEVSCEPSSCGPHETCRPSGG 3642
Score = 108 bits (271), Expect = 6e-23
Identities = 101/405 (24%), Positives = 162/405 (40%), Gaps = 47/405 (11%)
Query: 1941 GCRWTCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQ-------NKEQDLEVILHNGAC 1993
GC+ C H VT DG F G+C Y+L E + +
Sbjct: 4465 GCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG 4524
Query: 1994 SPGARQGCMKSIEVKHSALSVELHSDMEVTVNGRLVSVPY-VGGNMEVNVYGAIMHEVRF 2052
S ++++ + +L++ ++ V+G V++P+ + + ++ GA +
Sbjct: 4525 SQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTT 4584
Query: 2053 NHLGHIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQ 2112
+ L F + F P +A+ GLCG +++ A+D G W+
Sbjct: 4585 SGLSLAF----DGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGK-PAGWQVGGA 4639
Query: 2113 EWT---VQRPGQT-CQPILEEQCLVPDSSHCQVLLL---PLFAECHKVLAPATFYAICQQ 2165
+ V +P + C P +E PD+ C V+ PL A CH ++ PA ++ C
Sbjct: 4640 QGCGECVSKPCPSPCTPEQQESFGGPDA--CGVISATDGPL-APCHGLVPPAQYFQGCLL 4696
Query: 2166 DSC----HQEQVCEVIASYAHLCRTNGVCV-DWRTPDFCAMSCPPSLVYNHCEHGCPRHC 2220
D+C H +C +A+Y C+ G + +WR PDFC + CP Y C CP C
Sbjct: 4697 DACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSC 4756
Query: 2221 ------DGNVSSCGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWVPD 2274
+G S+C EGC C V+ +CVP C C+ DG + E + P
Sbjct: 4757 PSLSAPEGCESAC----REGCVCDAGFVLSGDTCVPVGQC-GCL-HDGRYYPLGEVFYPG 4810
Query: 2275 HQPCQICTCLSGRKVNCTTQPCPTAKAPTCGLCEVARLRQNADQC 2319
+ + C C G V C + CG E RL C
Sbjct: 4811 PECERRCECGPGGHVTC-------QEGAACGPHEECRLEDGVQAC 4848
Score = 107 bits (268), Expect = 1e-22
Identities = 122/491 (24%), Positives = 181/491 (36%), Gaps = 84/491 (17%)
Query: 804 CVSGCLCPPGMVRHENRCVALER-CPC-----FHQ-GKEYAPGETVKIGCN------TCV 850
CV GC C G V +RCV L C C +H+ G E+ T C + V
Sbjct: 1983 CVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLV 2042
Query: 851 CRDRKWNCTD---------HVCD----ATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDY 897
C + H C A C G HY+T DG ++ F G C+Y+L
Sbjct: 2043 CTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFNFQGTCEYLLSAPC 2102
Query: 898 CGSNPG--TFRILVGNKGCSHPSVKCKKRVTILVEGGEIEL---------FDGEVNVKRP 946
G G F + V N+ +V + VT+ + + L DG V V P
Sbjct: 2103 HGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDG-VFVTLP 2161
Query: 947 MKDETHFEVVESGRYIILLLGKALSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNND 1006
+ ++ SG +++ LS+ +D + + + Y +CGLCGN++ +D
Sbjct: 2162 FQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADD 2221
Query: 1007 LTSSNLQVEEDPVDFGNSWKV--SSQCADTRKVPLDSSPATCHNNIMKQTMVDSSCRIL- 1063
L + V P W+V + C + P P+ C + +C ++
Sbjct: 2222 LKA----VGGKPA----GWQVGGAQGCGECVSKP---CPSPCTPEQQESFGGPDACGVIS 2270
Query: 1064 -TSDVFQDCNKLVDPEPYLDVCIYDTCSCESIGDCACFCDTIAAYAHVCAQHG-KVVTWR 1121
T C+ LV P Y C+ D C + G C +A Y C G ++ WR
Sbjct: 2271 ATDGPLAPCHGLVPPAQYFQGCLLDACQVQ--GHPGGLCPAVATYVAACQAAGAQLREWR 2328
Query: 1122 TATLCPQSCEERNLRENGYECEWRYNSCAPACQVTCQH-PEPLACPVQCVEGCHAHCPPG 1180
CP C + Y C +C +C P C C EGC C G
Sbjct: 2329 RPDFCPFQCPAHS----------HYELCGDSCPGSCPSLSAPEGCESACREGC--VCDAG 2376
Query: 1181 KILDELLQTCVDPEDCPVCEVAGRRFASGKKVTLNPSDPEHCQICHC-DVVNLTC----- 1234
+L TCV C C R + G+ T P P +C C + ++C
Sbjct: 2377 FVLSG--DTCVPVGQCG-CLHDDRYYPLGQ--TFYPG-PGCDSLCRCREGGEVSCEPSSC 2430
Query: 1235 ---EACQEPGG 1242
E C+ GG
Sbjct: 2431 GPHETCRPSGG 2441
Score = 106 bits (265), Expect = 3e-22
Identities = 94/382 (24%), Positives = 155/382 (40%), Gaps = 40/382 (10%)
Query: 1941 GCRWTCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQ-------NKEQDLEVILHNGAC 1993
GC+ C H VT DG F G+C Y+L E + +
Sbjct: 2063 GCQPVSTAECQAWGDPHYVTLDGHRFNFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG 2122
Query: 1994 SPGARQGCMKSIEVKHSALSVELHSDMEVTVNGRLVSVPY-VGGNMEVNVYGAIMHEVRF 2052
S ++++ + +L++ ++ V+G V++P+ + + ++ GA +
Sbjct: 2123 SQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTT 2182
Query: 2053 NHLGHIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQ 2112
+ L F + F P +A GLCG +++ A+D G W+
Sbjct: 2183 SGLSLAF----DGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGK-PAGWQVGGA 2237
Query: 2113 EWT---VQRPGQT-CQPILEEQCLVPDSSHCQVLLL---PLFAECHKVLAPATFYAICQQ 2165
+ V +P + C P +E PD+ C V+ PL A CH ++ PA ++ C
Sbjct: 2238 QGCGECVSKPCPSPCTPEQQESFGGPDA--CGVISATDGPL-APCHGLVPPAQYFQGCLL 2294
Query: 2166 DSC----HQEQVCEVIASYAHLCRTNGVCV-DWRTPDFCAMSCPPSLVYNHCEHGCPRHC 2220
D+C H +C +A+Y C+ G + +WR PDFC CP Y C CP C
Sbjct: 2295 DACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSC 2354
Query: 2221 ------DGNVSSCGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWVPD 2274
+G S+C EGC C V+ +CVP C C+ +D + + + P
Sbjct: 2355 PSLSAPEGCESAC----REGCVCDAGFVLSGDTCVPVGQC-GCLHDDR-YYPLGQTFYPG 2408
Query: 2275 HQPCQICTCLSGRKVNCTTQPC 2296
+C C G +V+C C
Sbjct: 2409 PGCDSLCRCREGGEVSCEPSSC 2430
Score = 106 bits (264), Expect = 4e-22
Identities = 94/382 (24%), Positives = 155/382 (40%), Gaps = 40/382 (10%)
Query: 1941 GCRWTCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQ-------NKEQDLEVILHNGAC 1993
GC+ C H VT DG F G+C Y+L E + +
Sbjct: 3264 GCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG 3323
Query: 1994 SPGARQGCMKSIEVKHSALSVELHSDMEVTVNGRLVSVPY-VGGNMEVNVYGAIMHEVRF 2052
S ++++ + +L++ ++ V+G V++P+ + + ++ GA +
Sbjct: 3324 SQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTT 3383
Query: 2053 NHLGHIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQ 2112
+ L F + F P +A GLCG +++ A+D G W+
Sbjct: 3384 SGLSLAF----DGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGK-PAGWQVGGA 3438
Query: 2113 EWT---VQRPGQT-CQPILEEQCLVPDSSHCQVLLL---PLFAECHKVLAPATFYAICQQ 2165
+ V +P + C P +E PD+ C V+ PL A CH ++ PA ++ C
Sbjct: 3439 QGCGECVSKPCPSPCTPEQQESFGGPDA--CGVISATDGPL-APCHGLVPPAQYFQGCLL 3495
Query: 2166 DSC----HQEQVCEVIASYAHLCRTNGVCV-DWRTPDFCAMSCPPSLVYNHCEHGCPRHC 2220
D+C H +C +A+Y C+ G + +WR PDFC CP Y C CP C
Sbjct: 3496 DACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSC 3555
Query: 2221 ------DGNVSSCGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWVPD 2274
+G S+C EGC C V+ +CVP C C+ +D + + + P
Sbjct: 3556 PSLSAPEGCESAC----REGCVCDAGFVLSGDTCVPVGQC-GCLHDDR-YYPLGQTFYPG 3609
Query: 2275 HQPCQICTCLSGRKVNCTTQPC 2296
+C C G +V+C C
Sbjct: 3610 PGCDSLCRCREGGEVSCEPSSC 3631
Score = 105 bits (262), Expect = 6e-22
Identities = 127/503 (25%), Positives = 183/503 (36%), Gaps = 97/503 (19%)
Query: 1900 HTVTCQPDGQTLLKS----HRVNCDRGLRPSCPNSQSPVKVEETCGCRWTCP-------C 1948
H T P GQT +C G SC +S +CG C C
Sbjct: 1193 HQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESS--------SCGPHEACQPSGGSLGC 1244
Query: 1949 VCTGSST------RHIVTFDGQNFKLTGSCSYVLFQ--NKEQDLE--VILHNGACSPGAR 1998
V GSST H TFDG+ F G+C YVL Q L +L R
Sbjct: 1245 VAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGR 1304
Query: 1999 QGCMKSIEVKHSALSVELHS-DMEVTVNGRLVSVPYV--GGNMEVNVYGA-IMHEVRFN- 2053
+ I V+ + ++ L +VTVNG + +P V G + + +G+ ++ E F
Sbjct: 1305 VSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGL 1364
Query: 2054 ----HLGHIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKT 2109
L + T N +Q + GLCG + + +DF +G+ +
Sbjct: 1365 RVAYDLVYYVRVTVPGNYYQ----------QMCGLCGNYNGDPKDDFQKPNGSQAGNANE 1414
Query: 2110 LVQEWTVQRPGQTCQPIL-----EEQCL------------VPDSSHCQVLLLPL--FAEC 2150
W P C P E C+ C +L P + C
Sbjct: 1415 FGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSC 1474
Query: 2151 HKVLAPATFYAICQQDSC----HQEQVCEVIASYAHLCRTNGVCVD-WRTPDFCAMSCPP 2205
HK++ P C D C + +C I +Y C+ G V+ WRT FC M CPP
Sbjct: 1475 HKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPP 1534
Query: 2206 SLVYNHCEHGCPRHCDGNVS--SCGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDGV 2263
+ Y C C C + C D +EGC C + +CVP + C C +GV
Sbjct: 1535 NSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVPIQQC-GCY-HNGV 1592
Query: 2264 QHQFLEAWVPDHQPC-QICTCLSGRKVNCTTQPCP--------------TAKAP----TC 2304
++ + + D+ C Q CTC +G+ + C C K P TC
Sbjct: 1593 YYEPEQTVLIDN--CRQQCTCHAGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTC 1650
Query: 2305 GLCEVARLRQNADQCCPEYECVC 2327
E + + C P YE C
Sbjct: 1651 RPQETCKEQGGQGVCLPNYEATC 1673
Score = 101 bits (251), Expect = 1e-20
Identities = 128/511 (25%), Positives = 181/511 (35%), Gaps = 90/511 (17%)
Query: 1890 GDVWTLPDQC---HTVTCQPDGQTLLKSHRVN----CDRGLRPSC-PNSQSPVKVEETC- 1940
GD QC H P GQT + C G SC P+S P ETC
Sbjct: 2381 GDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSCGP---HETCR 2437
Query: 1941 ------GCRWTCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQ--NKEQDLE--VILHN 1990
GC C S H TFDG+ F G+C YVL Q L +L
Sbjct: 2438 PSGGSLGCVAVGSTTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQE 2497
Query: 1991 GACSPGARQGCMKSIEVKHSALSVELHS-DMEVTVNGRLVSVPYV--GGNMEVNVYGA-I 2046
R + I V+ + ++ L +VTVNG + +P V G + + +G+ +
Sbjct: 2498 NVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDV 2557
Query: 2047 MHEVRFN-----HLGHIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDG 2101
+ E F L + T N +QL GLCG + + +DF +G
Sbjct: 2558 VIETDFGLRVAYDLVYYVRVTVPGNYYQLMC----------GLCGNYNGDPKDDFQKPNG 2607
Query: 2102 TVTTDWKTLVQEWTVQRPGQTCQP-----------ILEEQC------LVPDSSHCQVLLL 2144
+ + W P C P I E+C C +L
Sbjct: 2608 SQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSEGCIPSEECPPELEKKYQKEEFCGLLSS 2667
Query: 2145 PL--FAECHKVLAPATFYAICQQDSC----HQEQVCEVIASYAHLCRTNGVCVD-WRTPD 2197
P + CHK++ P C D C + +C I +Y C+ G V+ WR
Sbjct: 2668 PTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGQVEPWRNET 2727
Query: 2198 FCAMSCPPSLVYNHCEHGCPRHCDGNVS--SCGDHPSEGCFCPPDKVMLEGSCVPEEACT 2255
FC M CP + Y C C C + C D +EGC C + +CVP + C
Sbjct: 2728 FCPMECPQNSHYELCADTCSLGCSALSAPLQCPDGCAEGCQCDSGFLYNGQACVPIQQC- 2786
Query: 2256 QCIGEDGVQHQFLEAWVPDHQPC-QICTCLSGRKVNCTTQPCPTAK-------------- 2300
C +G ++ + + D+ C Q CTC G+ V C C +
Sbjct: 2787 GCY-HNGAYYEPEQTVLIDN--CRQQCTCHVGKVVVCQEHSCKPGQVCQPSGGILSCVNK 2843
Query: 2301 ----APTCGLCEVARLRQNADQCCPEYECVC 2327
TC E + + C P YE C
Sbjct: 2844 DPCHGVTCRPQETCKEQGGQGVCLPNYEATC 2874
Score = 101 bits (251), Expect = 1e-20
Identities = 130/511 (25%), Positives = 182/511 (35%), Gaps = 90/511 (17%)
Query: 1890 GDVWTLPDQC---HTVTCQPDGQTLLKSHRVN----CDRGLRPSC-PNSQSPVKVEETC- 1940
GD QC H P GQT + C G SC P+S P ETC
Sbjct: 3582 GDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSCGP---HETCR 3638
Query: 1941 ------GCRWTCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQ--NKEQDLE--VILHN 1990
GC C S H TFDG F G+C YVL Q L +L
Sbjct: 3639 PSGGSLGCVAVGSTTCQASGDPHYTTFDGHRFDFMGTCVYVLAQTCGTRPGLHRFAVLQE 3698
Query: 1991 GACSPGARQGCMKSIEVKHSALSVELHS-DMEVTVNGRLVSVPYV--GGNMEVNVYGA-I 2046
R + I V+ + ++ L +VTVNG + +P V G + + +G+ +
Sbjct: 3699 NVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDV 3758
Query: 2047 MHEVRFN-----HLGHIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDG 2101
+ E F L + T N +QL GLCG + + +DF +G
Sbjct: 3759 VIETDFGLRVAYDLVYYVRVTVPGNYYQLMC----------GLCGNYNGDPKDDFQKPNG 3808
Query: 2102 TVTTDWKTLVQEWTVQRPGQTCQP-----------ILEEQC------LVPDSSHCQVLLL 2144
+ + W P C P I ++C C +L
Sbjct: 3809 SQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSAGCIPSDKCPPELEKKYQKEEFCGLLSS 3868
Query: 2145 PL--FAECHKVLAPATFYAICQQDSC----HQEQVCEVIASYAHLCRTNGVCVD-WRTPD 2197
P + CHK++ P C D C + +C I +Y C+ G V+ WR
Sbjct: 3869 PTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRNET 3928
Query: 2198 FCAMSCPPSLVYNHCEHGCPRHCDGNVS--SCGDHPSEGCFCPPDKVMLEGSCVPEEACT 2255
FC M CP + Y C C C + C D +EGC C + +CVP + C
Sbjct: 3929 FCPMECPQNSHYELCADTCSLGCSALSAPLQCPDGCAEGCQCDSGFLYNGQACVPIQQC- 3987
Query: 2256 QCIGEDGVQHQFLEAWVPDHQPC-QICTCLSGRKVNCTTQPCP--------------TAK 2300
C +GV ++ + + D+ C Q CTC G+ V C C K
Sbjct: 3988 GCY-HNGVYYEPEQTVLIDN--CRQQCTCHVGKVVVCQEHSCKPGQVCQPSGGILSCVTK 4044
Query: 2301 AP----TCGLCEVARLRQNADQCCPEYECVC 2327
P TC E + + C P YE C
Sbjct: 4045 DPCHGVTCRPQETCKEQGGQGVCLPNYEATC 4075
Score = 91.7 bits (226), Expect = 9e-18
Identities = 114/468 (24%), Positives = 166/468 (35%), Gaps = 75/468 (16%)
Query: 1897 DQCHTVTCQPDGQTLLKSHRVNCDRGLRPSC-PNSQSPVKVEETCGCRWTCPCVCTGSST 1955
D CH VTC+P Q K ++G + C PN E TC W P
Sbjct: 1643 DPCHGVTCRP--QETCK------EQGGQGVCLPN------YEATCWL-WGDP-------- 1679
Query: 1956 RHIVTFDGQNFKLTGSCSYVLFQN-----KEQDLE--VILHNGACSPGARQGCMKSIEVK 2008
H +FDG+ F G+C+YVL Q L + ++ + V
Sbjct: 1680 -HYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVA 1738
Query: 2009 HSALSVELHSDM--EVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHLGHIFTFTPQNN 2066
++ +H D +V VNG L ++P + ++V + G ++ N
Sbjct: 1739 ALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSY-DWNW 1797
Query: 2067 EFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTVQRPGQTCQPI 2126
+ L P ++ GLCG D N ND + +GT+ W C
Sbjct: 1798 RVDVTL-PSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDE 1856
Query: 2127 LEEQCLVPDSSHCQVLLLP------------LFAECHKVLAPATFYAICQQDSC----HQ 2170
C + P F CH + P +F+ C D C +
Sbjct: 1857 CRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDR 1916
Query: 2171 EQVCEVIASYAHLCRTNGVCV-DWRTPDFCAMSCPPSLVYNHCEHGCPRHCDG-----NV 2224
+ +C+ +ASY C+ GV + DWR C ++CP + Y C CP C
Sbjct: 1917 DILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGSPCPASCPSPAPLTTP 1976
Query: 2225 SSCGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWVPDHQPCQICTC- 2283
+ C EGC C V+ CVP C +G H+ + D Q C C
Sbjct: 1977 AVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGC-WANGTYHEAGSEFWADGTCSQWCRCG 2035
Query: 2284 LSGRKVNCTTQPCPTAKAPTCGLCEVARLRQNADQCCPEYECVCDPVS 2331
G + CT +CGL EV L P + C PVS
Sbjct: 2036 PGGGSLVCT--------PASCGLGEVCGL-------LPSGQHGCQPVS 2068
Score = 91.3 bits (225), Expect = 1e-17
Identities = 114/468 (24%), Positives = 166/468 (35%), Gaps = 75/468 (16%)
Query: 1897 DQCHTVTCQPDGQTLLKSHRVNCDRGLRPSC-PNSQSPVKVEETCGCRWTCPCVCTGSST 1955
D CH VTC+P Q K ++G + C PN E TC W P
Sbjct: 2844 DPCHGVTCRP--QETCK------EQGGQGVCLPN------YEATCWL-WGDP-------- 2880
Query: 1956 RHIVTFDGQNFKLTGSCSYVLFQN-----KEQDLE--VILHNGACSPGARQGCMKSIEVK 2008
H +FDG+ F G+C+YVL Q L + ++ + V
Sbjct: 2881 -HYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVA 2939
Query: 2009 HSALSVELHSDM--EVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHLGHIFTFTPQNN 2066
++ +H D +V VNG L ++P + ++V + G ++ N
Sbjct: 2940 ALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSY-DWNW 2998
Query: 2067 EFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTVQRPGQTCQPI 2126
+ L P ++ GLCG D N ND + +GT+ W C
Sbjct: 2999 RVDVTL-PSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDE 3057
Query: 2127 LEEQCLVPDSSHCQVLLLP------------LFAECHKVLAPATFYAICQQDSC----HQ 2170
C + P F CH + P +F+ C D C +
Sbjct: 3058 CRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDR 3117
Query: 2171 EQVCEVIASYAHLCRTNGVCV-DWRTPDFCAMSCPPSLVYNHCEHGCPRHCDG-----NV 2224
+ +C+ +ASY C+ GV + DWR C ++CP + Y C CP C
Sbjct: 3118 DILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTP 3177
Query: 2225 SSCGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWVPDHQPCQICTC- 2283
+ C EGC C V+ CVP C +G H+ + D Q C C
Sbjct: 3178 AVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGC-WANGTYHEAGSEFWADGTCSQWCRCG 3236
Query: 2284 LSGRKVNCTTQPCPTAKAPTCGLCEVARLRQNADQCCPEYECVCDPVS 2331
G + CT +CGL EV L P + C PVS
Sbjct: 3237 PGGGSLVCT--------PASCGLGEVCGL-------LPSGQHGCQPVS 3269
Score = 91.3 bits (225), Expect = 1e-17
Identities = 114/468 (24%), Positives = 166/468 (35%), Gaps = 75/468 (16%)
Query: 1897 DQCHTVTCQPDGQTLLKSHRVNCDRGLRPSC-PNSQSPVKVEETCGCRWTCPCVCTGSST 1955
D CH VTC+P Q K ++G + C PN E TC W P
Sbjct: 4045 DPCHGVTCRP--QETCK------EQGGQGVCLPN------YEATCWL-WGDP-------- 4081
Query: 1956 RHIVTFDGQNFKLTGSCSYVLFQN-----KEQDLE--VILHNGACSPGARQGCMKSIEVK 2008
H +FDG+ F G+C+YVL Q L + ++ + V
Sbjct: 4082 -HYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVA 4140
Query: 2009 HSALSVELHSDM--EVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHLGHIFTFTPQNN 2066
++ +H D +V VNG L ++P + ++V + G ++ N
Sbjct: 4141 ALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSY-DWNW 4199
Query: 2067 EFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTVQRPGQTCQPI 2126
+ L P ++ GLCG D N ND + +GT+ W C
Sbjct: 4200 RVDVTL-PSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDE 4258
Query: 2127 LEEQCLVPDSSHCQVLLLP------------LFAECHKVLAPATFYAICQQDSC----HQ 2170
C + P F CH + P +F+ C D C +
Sbjct: 4259 CRGSCPTCPEDRLEQYEGPGFCGPLSSGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDR 4318
Query: 2171 EQVCEVIASYAHLCRTNGVCV-DWRTPDFCAMSCPPSLVYNHCEHGCPRHCDG-----NV 2224
+ +C+ +ASY C+ GV + DWR C ++CP + Y C CP C
Sbjct: 4319 DILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTP 4378
Query: 2225 SSCGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWVPDHQPCQICTC- 2283
+ C EGC C V+ CVP C +G H+ + D Q C C
Sbjct: 4379 AVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGC-WANGTYHEAGSEFWADGTCSQWCRCG 4437
Query: 2284 LSGRKVNCTTQPCPTAKAPTCGLCEVARLRQNADQCCPEYECVCDPVS 2331
G + CT +CGL EV L P + C PVS
Sbjct: 4438 PGGGSLVCT--------PASCGLGEVCGL-------LPSGQHGCQPVS 4470
Score = 56.2 bits (134), Expect = 4e-07
Identities = 103/444 (23%), Positives = 160/444 (36%), Gaps = 96/444 (21%)
Query: 618 GREC-LCG----------ALASYAAACAGRGVRVAWREPGRCELNCPKGQVYLQCGTPCN 666
GR C LCG L + +AA + AWR PG + C +G CG
Sbjct: 4980 GRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSK-GCGEG-----CGPQGC 5033
Query: 667 LTCRSLSYPDEECNEACLEGCFCPPGLYMDERGDCVPKAQCPCYYDGEIFQPEDIFSDH- 725
C + E NEAC G + +G P A C + P + F
Sbjct: 5034 PVCLAEETAPYESNEAC--------GQLRNPQG---PFATCQA-----VLSPSEYFRQCV 5077
Query: 726 HTMCYC--EDGFMHCTMSGVPGSLLPDAVLSSPLSHRSKRSLSCRPPMVKLVCPADNLRA 783
+ +C + F+ +++ + V P S L CPA + +
Sbjct: 5078 YDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDS---------FCPLHCPAHSHYS 5128
Query: 784 EGLECTKTCQNY-----DLECMSMGCVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAP 838
CT+TCQ L + C GC C + + C+ ++ C C H G+ Y P
Sbjct: 5129 I---CTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCIPVQDCGCTHNGR-YLP 5184
Query: 839 GETVKIGCNTCVCRDRKWNCTD--------------HVCDATC------STIGM------ 872
V T C +R +C+ VC+ +T G+
Sbjct: 5185 ---VNSSLLTSDCSER-CSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWATRGLCVLSVG 5240
Query: 873 AHYLTFDGLKYLFPGECQYVLVQDYCGSNPGT---FRILVGNKGCSHPSVKCKKRVTILV 929
A+ TFDG + Y L C T +R++ + C H + +V I
Sbjct: 5241 ANLTTFDGARGATTSPGVYEL-SSRCPGLQNTIPWYRVVAEVQIC-HGKTEAVGQVHIFF 5298
Query: 930 EGGEIELFDGE------VNVKRPMKDETHFEVVESGRYIILLLGKALSVVW-DRHLSISV 982
+ G + L + + V P + V + +L+ KA VW + ++V
Sbjct: 5299 QDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDGSLLVRQKAGVQVWLGANGKVAV 5358
Query: 983 VLKQTYQEKVCGLCGNFDGIQNND 1006
++ + K+CG CGNFDG Q ND
Sbjct: 5359 IVSNDHAGKLCGACGNFDGDQTND 5382
Score = 39.3 bits (90), Expect = 0.055
Identities = 45/169 (26%), Positives = 66/169 (39%), Gaps = 29/169 (17%)
Query: 2546 NVSCPQLEVPV-CPSGFQLSCKTS--------ACCPSCRCERMEACMLNGTVIGPGKTVM 2596
++ C L P+ CP G C+ AC P +C C NG P +TV+
Sbjct: 2747 SLGCSALSAPLQCPDGCAEGCQCDSGFLYNGQACVPIQQC----GCYHNGAYYEPEQTVL 2802
Query: 2597 IDVCTTCRCMVQVGVISGFKLECRKTTCNPCPL-----GYKEENNTGECCGRCLPTACTI 2651
ID C +C VG + + C++ +C P + G N C G T
Sbjct: 2803 IDNCRQ-QCTCHVGKV----VVCQEHSCKPGQVCQPSGGILSCVNKDPCHGVTCRPQETC 2857
Query: 2652 QLRGGQIMTLKRDE-TLQDGCDTHF-----CKVNERGEYFWEKRVTGCP 2694
+ +GGQ + L E T D H+ K + +G + TGCP
Sbjct: 2858 KEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCP 2906
Score = 37.4 bits (85), Expect = 0.21
Identities = 26/90 (28%), Positives = 39/90 (43%), Gaps = 18/90 (20%)
Query: 2546 NVSCPQLEVPV-CPSGFQLSCKTS--------ACCPSCRCERMEACMLNGTVIGPGKTVM 2596
++ C L P+ CP G C+ AC P +C C NG P +TV+
Sbjct: 3948 SLGCSALSAPLQCPDGCAEGCQCDSGFLYNGQACVPIQQC----GCYHNGVYYEPEQTVL 4003
Query: 2597 IDVCTTCRCMVQVGVISGFKLECRKTTCNP 2626
ID C +C VG + + C++ +C P
Sbjct: 4004 IDNCRQ-QCTCHVGKV----VVCQEHSCKP 4028
Score = 35.4 bits (80), Expect = 0.80
Identities = 34/121 (28%), Positives = 50/121 (41%), Gaps = 23/121 (19%)
Query: 2368 KRVSPPSCPPHRLPTLRKTQCCDEYECACNCVNSTVSCPLGYLASTATNDCGC------T 2421
+ + P SCPPH + C Y C +C + V G S C C +
Sbjct: 1129 EELCPLSCPPHS-----HYEACS-YGCPLSCGDLPVP---GGCGSECHEGCVCDEGFALS 1179
Query: 2422 TTTCLP--DKVCVHRSTIYPVGQ--FWEEGCD-VCTCTDMEDAVMGLRVAQCS-QKPCED 2475
+CLP CVH+ T +P GQ + GCD +C C E ++ + C + C+
Sbjct: 1180 GESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHC--QEGGLVSCESSSCGPHEACQP 1237
Query: 2476 S 2476
S
Sbjct: 1238 S 1238
Score = 34.7 bits (78), Expect = 1.4
Identities = 23/71 (32%), Positives = 33/71 (46%), Gaps = 13/71 (18%)
Query: 2557 CPSGFQLSCKTSACCPSCRCERMEACMLNGTVIGPGKTVMIDVC-TTCRCMVQVGVISGF 2615
C SGF + + AC P +C C NG P +TV+ID C C C G++
Sbjct: 1568 CDSGFLYNGQ--ACVPIQQC----GCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMV--- 1618
Query: 2616 KLECRKTTCNP 2626
C++ +C P
Sbjct: 1619 ---CQEHSCKP 1626
Score = 32.0 bits (71), Expect = 8.8
Identities = 49/178 (27%), Positives = 62/178 (34%), Gaps = 40/178 (22%)
Query: 2494 CLPSACEVVTGSPRG------DSQSSWKSVGSQ---WASPENPCLINECVRVKEEVFIQQ 2544
CL AC+V G P G ++ ++ G+Q W P+ C + E+
Sbjct: 4694 CLLDACQV-QGHPGGLCPAVATYVAACQAAGAQLGEWRRPDF-CPLQCPAHSHYELCGDS 4751
Query: 2545 RNVSCPQLEVP-----------VCPSGFQLSCKTSACCPSCRCERMEACMLNGTVIGPGK 2593
VSCP L P VC +GF LS T C C G V PG
Sbjct: 4752 CPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGP 4811
Query: 2594 TVMIDVCTTCRC------MVQVGVISGFKLECRKTTCNPCPLGYKEENNTGECCGRCL 2645
+ C C Q G G ECR G + + TG CGRCL
Sbjct: 4812 ----ECERRCECGPGGHVTCQEGAACGPHEECRLED------GVQACHATG--CGRCL 4857
>gi|239757282 PREDICTED: similar to Fc fragment of IgG binding protein
[Homo sapiens]
Length = 1403
Score = 305 bits (781), Expect = 4e-82
Identities = 226/774 (29%), Positives = 314/774 (40%), Gaps = 89/774 (11%)
Query: 31 STARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQ-----KRSFSI-IGDFQNGKR--- 81
STA C +G T DG + F G C YLL+ C +F++ + + G +
Sbjct: 470 STAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVS 529
Query: 82 ----VSLSVY-----LGEFFDIHLFVNGTVTQGDQRVSMPYASKGLYLETEAGYYKLSGE 132
V+L +Y L + L V+G V++P+ L +G +
Sbjct: 530 YTRSVTLQIYNHSLTLSARWPRKLQVDGVF------VALPFQLDSLLHAHLSGADVVVTT 583
Query: 133 AYGFVARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWA 192
G DG ++ + Y CGLCGN+N DD G W
Sbjct: 584 TSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAG--------WQ 635
Query: 193 LSSGEQWCERASPPSSSCNISSGEMQKGLWEQCQLLKSTS-VFARCHPLVDPEPFVALCE 251
+ + E S P S + G + C ++ +T A CH LV P + C
Sbjct: 636 VGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCL 695
Query: 252 KTLCECAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCART 311
C+ G CPA+ Y C G L W C CPA Y C C +
Sbjct: 696 LDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVS 755
Query: 312 CQSLHINEMCQERCVDGCSCPEGQLLDEGLCVESTECPCVHSGKRYP------PGTSLSR 365
C SL E C+ C +GC C G +L CV +C C+H G+ YP PG R
Sbjct: 756 CPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECER 815
Query: 366 DCNT-----CICRNSQWICSNEECP-------------GECLVTGQSHFKSFDNRYFTFS 407
C C+ +EEC G CL G H+ + D R +
Sbjct: 816 RCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLH 875
Query: 408 GICQYLLARDCQ----DHSFSIVIETVQCADDRDAVCTRSVTVRLPGLHNSLVKLKHGAG 463
G C Y+LA+ C D FSIV+E D + + T + +V L G
Sbjct: 876 GSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRLLVT---------VAGQVVSLAQGQQ 926
Query: 464 VAMDGQDVQLPLLKGDLRIQHTVTASVR---LSYGEDLQMDWDGRGRLLVKLSPVYAGKT 520
V +DG+ V LP+ G +R VTA R L + L++ +DG LL+ + + G+
Sbjct: 927 VTVDGEAVALPVAVGRVR----VTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRL 982
Query: 521 CGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWKLHGDCQDLQK----QHSDPCALNPRM 576
CGLCGN+NGN DDF+ P+G A VE FG AW++ G + + Q C
Sbjct: 983 CGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGSSKGCGEGCGPQGCPVCLAEETA 1042
Query: 577 TRFSEEACAVLTSP--TFEACHRAVSPLPYLRNCRYDVCSCSDGRECLCGALASYAAACA 634
S EAC L +P F C +SP Y R C YD+C+ + LC +LA+Y AAC
Sbjct: 1043 PYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQ 1102
Query: 635 GRGVRV-AWREPGRCELNCPKGQVYLQCGTPCNLTCRSLSYPDEECNEACLEGCFCPPGL 693
GV V WR C L+CP Y C C +C +LS C C EGC C
Sbjct: 1103 AAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALS-GLTGCTTRCFEGCECDDRF 1161
Query: 694 YMDERGDCVPKAQCPCYYDGEIFQPED--IFSDHHTMCYCEDGF-MHCTMSGVP 744
+ + G C+P C C ++G + SD C C + C +G P
Sbjct: 1162 LLSQ-GVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCP 1214
Score = 276 bits (706), Expect = 2e-73
Identities = 219/764 (28%), Positives = 302/764 (39%), Gaps = 76/764 (9%)
Query: 33 ARCSLFGSDFVNTFDGSMYSFAGYCSYLLAG-GCQKRS------FSIIGDFQNGKRVSLS 85
A C L+G ++FDG + F G C+Y+LA GC S F++ +N ++S
Sbjct: 73 ATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCLGVSTQGLTPFTVTTKNENRGNPAVS 132
Query: 86 VY-------LGEFFDIHLFVNGTVTQGDQRVSMPYASKGLYLETEAGYYK-LSGEAYGFV 137
LG IH G V ++P + + G K L +G
Sbjct: 133 YVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQ 192
Query: 138 ARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGE 197
D + V L Y CGLCGN + +D + GTL + SW +
Sbjct: 193 VSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWD 252
Query: 198 QWC-ERASPPSSSCNISSGEMQKGLWEQCQLLKSTS-VFARCHPLVDPEPFVALCEKTLC 255
C + +C E +G L T F CH V PE F C +C
Sbjct: 253 PLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVC 312
Query: 256 ECAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCARTCQS- 314
G + C AL Y C G+V+ W C CP Y C PC +C S
Sbjct: 313 MGGGDHDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSP 372
Query: 315 --LHINEMCQERCVDGCSCPEGQLLDEGLCVE-STECPCVHSGKRYPPGTSLSRDCNTCI 371
L +C+ CV+GC C G +L CV + C C +G + G+ D TC
Sbjct: 373 APLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWAD-GTC- 430
Query: 372 CRNSQW----------ICSNEEC--------------------PGECLVTGQSHFKSFDN 401
SQW +C+ C EC G H+ + D
Sbjct: 431 ---SQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDG 487
Query: 402 RYFTFSGICQYLLARDCQDHSFSIVIETVQCADDR---DAVC-TRSVTVRLPGLHNSLVK 457
F F G C+YLL+ C TV A++ AV TRSVT+++ H+ +
Sbjct: 488 HRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYN-HSLTLS 546
Query: 458 LKHGAGVAMDGQDVQLPLLKGDLRIQHTVTASVRLSYGEDLQMDWDGRGRLLVKLSPVYA 517
+ + +DG V LP L H A V ++ L + +DG + +++ YA
Sbjct: 547 ARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYA 606
Query: 518 GKTCGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWKLHGDCQDLQKQHSDPCALNPRMT 577
CGLCGNYN + DD G +P G A G+C + K PC + +
Sbjct: 607 ASLCGLCGNYNQDPADDLKAVGG--KPAGWQVGGAQGC-GEC--VSKPCPSPCTPEQQES 661
Query: 578 RFSEEACAVL--TSPTFEACHRAVSPLPYLRNCRYDVCSCSDGRECLCGALASYAAACAG 635
+AC V+ T CH V P Y + C D C LC A+A+Y AAC
Sbjct: 662 FGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQA 721
Query: 636 RGVRVA-WREPGRCELNCPKGQVYLQCGTPCNLTCRSLSYPDEECNEACLEGCFCPPGLY 694
G ++ WR P C L CP Y CG C ++C SLS P E C AC EGC C G
Sbjct: 722 AGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAP-EGCESACREGCVCDAGFV 780
Query: 695 MDERGD-CVPKAQCPCYYDGEIFQPEDIF---SDHHTMCYCEDG 734
+ GD CVP QC C +DG + ++F + C C G
Sbjct: 781 LS--GDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPG 822
Score = 177 bits (449), Expect = 1e-43
Identities = 144/542 (26%), Positives = 217/542 (40%), Gaps = 53/542 (9%)
Query: 34 RCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKR----SFSII------GDFQNGKRVS 83
RC G T DG +Y G CSY+LA C + FSI+ GD Q
Sbjct: 855 RCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQR----L 910
Query: 84 LSVYLGEFFDIHLFVNGTVTQGDQRVSMPYASKGLYLETEAGYYKLSGEAYGFVARIDGS 143
L G+ + L VT + V++P A G T G + G DG
Sbjct: 911 LVTVAGQV--VSLAQGQQVTVDGEAVALPVAV-GRVRVTAEGRNMVLQTTKGLRLLFDGD 967
Query: 144 GNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGEQWCERA 203
+ + + + + CGLCGNFN DDF+ G+ S F +W + + C
Sbjct: 968 AHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGSSKGCGEG 1027
Query: 204 SPPSSSCNISSGEMQKGLW--EQC-QLLKSTSVFARCHPLVDPEPFVALCEKTLCECAGG 260
P C + E E C QL FA C ++ P + C LC G
Sbjct: 1028 CGPQG-CPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGD 1086
Query: 261 LECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCARTCQSLHINEM 320
C +L Y C G+ + W S C CPA Y C C +C +L
Sbjct: 1087 KAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTG 1146
Query: 321 CQERCVDGCSCPEGQLLDEGLCVESTECPCVHSGKRYPPGTS-LSRDCN-TCICRNSQWI 378
C RC +GC C + LL +G+C+ +C C H+G+ P +S L+ DC+ C C +S +
Sbjct: 1147 CTTRCFEGCECDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGL 1206
Query: 379 -CSNEECP------------------GECLVTGQSHFKSFDNRYFTFSGICQYLLARDCQ 419
C CP G C+++ ++ +FD + Y L+ C
Sbjct: 1207 TCQAAGCPPGRVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGATTSPGVYELSSRCP 1266
Query: 420 DHS-----FSIVIETVQCADDRDAVCTRSVTVRLPGLHNSLVKLKHGAGVAMDGQDVQLP 474
+ +V E C +AV + + +V L GV ++G V LP
Sbjct: 1267 GLQNTIPWYRVVAEVQICHGKTEAVGQVHIF-----FQDGMVTLTPNKGVWVNGLRVDLP 1321
Query: 475 LLK-GDLRIQHTVTASVRLSYGEDLQMDWDGRGRLLVKLSPVYAGKTCGLCGNYNGNQGD 533
K + + T S+ + +Q+ G++ V +S +AGK CG CGN++G+Q +
Sbjct: 1322 AEKLASVSVSRTPDGSLLVRQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTN 1381
Query: 534 DF 535
D+
Sbjct: 1382 DW 1383
Score = 154 bits (390), Expect = 9e-37
Identities = 150/550 (27%), Positives = 211/550 (38%), Gaps = 73/550 (13%)
Query: 738 CTMSGVPGSLLPDAVLSSPLSHRSKRSLS--CRPPMVKLVCPA-DNLRAEGLECTKTCQN 794
C + G PG L P + L RP L CPA + G C +C +
Sbjct: 699 CQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPS 758
Query: 795 YDL-ECMSMGCVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAPGETVKIG--CNT-CV 850
E C GC+C G V + CV + +C C H G+ Y GE G C C
Sbjct: 759 LSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCE 818
Query: 851 CR-------DRKWNCTDH----------VCDAT----CSTIGMAHYLTFDGLKYLFPGEC 889
C C H C AT C G HY+T DG Y G C
Sbjct: 819 CGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSC 878
Query: 890 QYVLVQDYCGSNPGT--FRILVGNKGCSHPS---VKCKKRVTILVEGGEIELFDGEVNVK 944
YVL Q C PG F I++ V +V L +G ++ + DGE V
Sbjct: 879 SYVLAQ-VCHPKPGDEDFSIVLEKNAAGDLQRLLVTVAGQVVSLAQGQQVTV-DGEA-VA 935
Query: 945 RPMKDETHFEVVESGRYIILLLGKALSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQN 1004
P+ V GR ++L K L +++D + + + ++ ++CGLCGNF+G +
Sbjct: 936 LPVA-VGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWS 994
Query: 1005 NDLTSSNLQVEEDPVDFGNSWKV---SSQCADTRKVPLDSSPATCHNNIMKQTM---VDS 1058
+D N FG +W+V S C + P C + ++T +
Sbjct: 995 DDFVLPNGSAASSVETFGAAWRVPGSSKGCGE------GCGPQGCPVCLAEETAPYESNE 1048
Query: 1059 SCRILTS--DVFQDCNKLVDPEPYLDVCIYDTCSCESIGDCACFCDTIAAYAHVCAQHGK 1116
+C L + F C ++ P Y C+YD C+ + GD A C ++AAY C G
Sbjct: 1049 ACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQK--GDKAFLCRSLAAYTAACQAAGV 1106
Query: 1117 VV-TWRTATLCPQSCEERNLRENGYECEWRYNSCAPACQVTCQHPEPL-ACPVQCVEGCH 1174
V WRT + CP C + Y+ C CQ +C L C +C EGC
Sbjct: 1107 AVKPWRTDSFCPLHCPAHS----------HYSICTRTCQGSCAALSGLTGCTTRCFEGC- 1155
Query: 1175 AHCPPGKILDELLQTCVDPEDCPVCEVAGRRFASGKKVTLNPSDPEHCQICHCDVVNLTC 1234
C +L + C+ +DC C GR + L E C LTC
Sbjct: 1156 -ECDDRFLLSQ--GVCIPVQDCG-CTHNGRYLPVNSSL-LTSDCSERCSCSSSS--GLTC 1208
Query: 1235 EACQEPGGLV 1244
+A P G V
Sbjct: 1209 QAAGCPPGRV 1218
Score = 134 bits (336), Expect = 2e-30
Identities = 119/462 (25%), Positives = 184/462 (39%), Gaps = 60/462 (12%)
Query: 1883 DGNEKRPGDVWTLPDQCHT-VTCQPDGQTLLKSHRVNCDRGLRPSCPNSQSPVKVEETCG 1941
DG G+V+ +C C P G V C G +C + +
Sbjct: 797 DGRYYPLGEVFYPGPECERRCECGPGGH-------VTCQEGA--ACGPHEECRLEDGVQA 847
Query: 1942 CRWTCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQ-----NKEQDLEVILHNGACSPG 1996
C T C + H +T DG+ + L GSCSYVL Q ++D ++L A
Sbjct: 848 CHATGCGRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAA--- 904
Query: 1997 ARQGCMKSIEVKHSALSVELHSDMEVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHLG 2056
G ++ + V + V L +VTV+G V++P G + V G M L
Sbjct: 905 ---GDLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLR 961
Query: 2057 HIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTV 2116
+F + L P F + GLCG + N ++DF+L +G+ + +T W V
Sbjct: 962 LLF----DGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRV 1017
Query: 2117 ----QRPGQTCQP------ILEEQCLVPDSSHCQVLLLPL--FAECHKVLAPATFYAICQ 2164
+ G+ C P + EE + C L P FA C VL+P+ ++ C
Sbjct: 1018 PGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCV 1077
Query: 2165 QDSCHQEQ----VCEVIASYAHLCRTNGVCV-DWRTPDFCAMSCPPSLVYNHCEHGCPRH 2219
D C Q+ +C +A+Y C+ GV V WRT FC + CP Y+ C C
Sbjct: 1078 YDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGS 1137
Query: 2220 CD--GNVSSCGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQF----LEAWVP 2273
C ++ C EGC C ++ +G C+P + C G H + + +
Sbjct: 1138 CAALSGLTGCTTRCFEGCECDDRFLLSQGVCIPVQDC-------GCTHNGRYLPVNSSLL 1190
Query: 2274 DHQPCQICTCLSGRKVNCTTQPCPTAKAPTCGLCEVARLRQN 2315
+ C+C S + C CP + +CEV +N
Sbjct: 1191 TSDCSERCSCSSSSGLTCQAAGCPPGR-----VCEVKAEARN 1227
Score = 128 bits (321), Expect = 9e-29
Identities = 115/416 (27%), Positives = 160/416 (38%), Gaps = 60/416 (14%)
Query: 846 CNTCVCRDRKWNCTDH----VC----DATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDY 897
C+ CR ++ C + VC +ATC G HY +FDG K+ F G C YVL
Sbjct: 47 CHGVTCRPQE-TCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTG 105
Query: 898 C------GSNPGTFRILVGNKGCSHPSVKCKKRVTILVEGGEIELFDGEVNVKR------ 945
C G P F + N+ +P+V + VT+ G I + E+ R
Sbjct: 106 CLGVSTQGLTP--FTVTTKNENRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLT 163
Query: 946 --PMK-DETHFEVVESGRYIILLLGKALSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGI 1002
P+ + V + +L+ L V +D + + V L +Y VCGLCGN D
Sbjct: 164 ALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRN 223
Query: 1003 QNNDLTSSNLQVEEDPVDFGNSWKV---SSQCADTRKVPLDSSPATCHNNIMKQTMVDSS 1059
NND N + +G SW+ C D + S TC + ++Q
Sbjct: 224 PNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECR----GSCPTCPEDRLEQYEGPGF 279
Query: 1060 CRIL---TSDVFQDCNKLVDPEPYLDVCIYDTCSCESIGDCACFCDTIAAYAHVCAQHGK 1116
C L T F C+ V PE + C+ D C GD C +A+Y C G
Sbjct: 280 CGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCM--GGGDHDILCKALASYVAACQAAGV 337
Query: 1117 VV-TWRTATLCPQSCEERNLRENGYECEWRYNSCAPACQVTCQHPEPLACPV----QCVE 1171
V+ WR C +C E + Y C P C +C P PL P CVE
Sbjct: 338 VIEDWRAQVGCEITCPENS----------HYEVCGPPCPASCPSPAPLTTPAVCEGPCVE 387
Query: 1172 GCHAHCPPGKILDELLQTCVDPEDCPVCEVAGRRFASGKKVTLNPSDPEHCQICHC 1227
GC C G +L CV + C G +G + +D Q C C
Sbjct: 388 GC--QCDAGFVLS--ADRCVPLNNGCGCWANGTYHEAGSEFW---ADGTCSQWCRC 436
Score = 115 bits (288), Expect = 6e-25
Identities = 124/500 (24%), Positives = 180/500 (36%), Gaps = 85/500 (17%)
Query: 767 CRPPMVKLVCPADNLRAEGLECTKTCQNYDLECMSMGCVSGCLCPPGMVRHENRCVALER 826
C PP CPA L C+ CV GC C G V +RCV L
Sbjct: 361 CGPP-----CPASCPSPAPLTTPAVCEG--------PCVEGCQCDAGFVLSADRCVPLNN 407
Query: 827 -CPC-----FHQ-GKEYAPGETVKIGCN------TCVCRDRKWNCTD---------HVCD 864
C C +H+ G E+ T C + VC + H C
Sbjct: 408 GCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQ 467
Query: 865 ----ATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPG--TFRILVGNKGCSHPS 918
A C G HY+T DG ++ F G C+Y+L G G F + V N+ +
Sbjct: 468 PVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQA 527
Query: 919 VKCKKRVTILVEGGEIEL---------FDGEVNVKRPMKDETHFEVVESGRYIILLLGKA 969
V + VT+ + + L DG V V P + ++ SG +++
Sbjct: 528 VSYTRSVTLQIYNHSLTLSARWPRKLQVDG-VFVALPFQLDSLLHAHLSGADVVVTTTSG 586
Query: 970 LSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKV-- 1027
LS+ +D + + + Y +CGLCGN++ +DL + V P W+V
Sbjct: 587 LSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKA----VGGKPA----GWQVGG 638
Query: 1028 SSQCADTRKVPLDSSPATCHNNIMKQTMVDSSCRIL--TSDVFQDCNKLVDPEPYLDVCI 1085
+ C + P P+ C + +C ++ T C+ LV P Y C+
Sbjct: 639 AQGCGECVSKP---CPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCL 695
Query: 1086 YDTCSCESIGDCACFCDTIAAYAHVCAQHG-KVVTWRTATLCPQSCEERNLRENGYECEW 1144
D C + G C +A Y C G ++ WR CP C +
Sbjct: 696 LDACQVQ--GHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHS---------- 743
Query: 1145 RYNSCAPACQVTCQH-PEPLACPVQCVEGCHAHCPPGKILDELLQTCVDPEDCPVCEVAG 1203
Y C +C V+C P C C EGC C G +L TCV C C G
Sbjct: 744 HYELCGDSCPVSCPSLSAPEGCESACREGC--VCDAGFVLSG--DTCVPVGQCG-CLHDG 798
Query: 1204 RRFASGKKVTLNPSDPEHCQ 1223
R + G+ P C+
Sbjct: 799 RYYPLGEVFYPGPECERRCE 818
Score = 108 bits (271), Expect = 6e-23
Identities = 101/405 (24%), Positives = 162/405 (40%), Gaps = 47/405 (11%)
Query: 1941 GCRWTCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQ-------NKEQDLEVILHNGAC 1993
GC+ C H VT DG F G+C Y+L E + +
Sbjct: 465 GCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG 524
Query: 1994 SPGARQGCMKSIEVKHSALSVELHSDMEVTVNGRLVSVPY-VGGNMEVNVYGAIMHEVRF 2052
S ++++ + +L++ ++ V+G V++P+ + + ++ GA +
Sbjct: 525 SQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTT 584
Query: 2053 NHLGHIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQ 2112
+ L F + F P +A+ GLCG +++ A+D G W+
Sbjct: 585 SGLSLAF----DGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGK-PAGWQVGGA 639
Query: 2113 EWT---VQRPGQT-CQPILEEQCLVPDSSHCQVLLL---PLFAECHKVLAPATFYAICQQ 2165
+ V +P + C P +E PD+ C V+ PL A CH ++ PA ++ C
Sbjct: 640 QGCGECVSKPCPSPCTPEQQESFGGPDA--CGVISATDGPL-APCHGLVPPAQYFQGCLL 696
Query: 2166 DSC----HQEQVCEVIASYAHLCRTNGVCV-DWRTPDFCAMSCPPSLVYNHCEHGCPRHC 2220
D+C H +C +A+Y C+ G + +WR PDFC + CP Y C CP C
Sbjct: 697 DACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSC 756
Query: 2221 ------DGNVSSCGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWVPD 2274
+G S+C EGC C V+ +CVP C C+ DG + E + P
Sbjct: 757 PSLSAPEGCESAC----REGCVCDAGFVLSGDTCVPVGQC-GCL-HDGRYYPLGEVFYPG 810
Query: 2275 HQPCQICTCLSGRKVNCTTQPCPTAKAPTCGLCEVARLRQNADQC 2319
+ + C C G V C + CG E RL C
Sbjct: 811 PECERRCECGPGGHVTC-------QEGAACGPHEECRLEDGVQAC 848
Score = 93.6 bits (231), Expect = 2e-18
Identities = 115/469 (24%), Positives = 166/469 (35%), Gaps = 75/469 (15%)
Query: 1896 PDQCHTVTCQPDGQTLLKSHRVNCDRGLRPSC-PNSQSPVKVEETCGCRWTCPCVCTGSS 1954
PD CH VTC+P Q K ++G + C PN E TC W P
Sbjct: 44 PDPCHGVTCRP--QETCK------EQGGQGVCLPN------YEATCWL-WGDP------- 81
Query: 1955 TRHIVTFDGQNFKLTGSCSYVLFQN-----KEQDLE--VILHNGACSPGARQGCMKSIEV 2007
H +FDG+ F G+C+YVL Q L + ++ + V
Sbjct: 82 --HYHSFDGRKFDFQGTCNYVLATTGCLGVSTQGLTPFTVTTKNENRGNPAVSYVRVVTV 139
Query: 2008 KHSALSVELHSDM--EVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHLGHIFTFTPQN 2065
++ +H D +V VNG L ++P + ++V + G ++ N
Sbjct: 140 AALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSY-DWN 198
Query: 2066 NEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTVQRPGQTCQP 2125
+ L P ++ GLCG D N ND + +GT+ W C
Sbjct: 199 WRVDVTL-PSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWD 257
Query: 2126 ILEEQCLVPDSSHCQVLLLP------------LFAECHKVLAPATFYAICQQDSC----H 2169
C + P F CH + P +F+ C D C
Sbjct: 258 ECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGD 317
Query: 2170 QEQVCEVIASYAHLCRTNGVCV-DWRTPDFCAMSCPPSLVYNHCEHGCPRHCDG-----N 2223
+ +C+ +ASY C+ GV + DWR C ++CP + Y C CP C
Sbjct: 318 HDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTT 377
Query: 2224 VSSCGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWVPDHQPCQICTC 2283
+ C EGC C V+ CVP C +G H+ + D Q C C
Sbjct: 378 PAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGC-WANGTYHEAGSEFWADGTCSQWCRC 436
Query: 2284 -LSGRKVNCTTQPCPTAKAPTCGLCEVARLRQNADQCCPEYECVCDPVS 2331
G + CT +CGL EV L P + C PVS
Sbjct: 437 GPGGGSLVCT--------PASCGLGEVCGL-------LPSGQHGCQPVS 470
Score = 55.8 bits (133), Expect = 6e-07
Identities = 103/444 (23%), Positives = 160/444 (36%), Gaps = 96/444 (21%)
Query: 618 GREC-LCG----------ALASYAAACAGRGVRVAWREPGRCELNCPKGQVYLQCGTPCN 666
GR C LCG L + +AA + AWR PG + C +G CG
Sbjct: 980 GRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGSSK-GCGEG-----CGPQGC 1033
Query: 667 LTCRSLSYPDEECNEACLEGCFCPPGLYMDERGDCVPKAQCPCYYDGEIFQPEDIFSDH- 725
C + E NEAC G + +G P A C + P + F
Sbjct: 1034 PVCLAEETAPYESNEAC--------GQLRNPQG---PFATCQA-----VLSPSEYFRQCV 1077
Query: 726 HTMCYC--EDGFMHCTMSGVPGSLLPDAVLSSPLSHRSKRSLSCRPPMVKLVCPADNLRA 783
+ +C + F+ +++ + V P S L CPA + +
Sbjct: 1078 YDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDS---------FCPLHCPAHSHYS 1128
Query: 784 EGLECTKTCQNY-----DLECMSMGCVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAP 838
CT+TCQ L + C GC C + + C+ ++ C C H G+ Y P
Sbjct: 1129 I---CTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCIPVQDCGCTHNGR-YLP 1184
Query: 839 GETVKIGCNTCVCRDRKWNCTD--------------HVCDATC------STIGM------ 872
V T C +R +C+ VC+ +T G+
Sbjct: 1185 ---VNSSLLTSDCSER-CSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWATRGLCVLSVG 1240
Query: 873 AHYLTFDGLKYLFPGECQYVLVQDYCGSNPGT---FRILVGNKGCSHPSVKCKKRVTILV 929
A+ TFDG + Y L C T +R++ + C H + +V I
Sbjct: 1241 ANLTTFDGARGATTSPGVYEL-SSRCPGLQNTIPWYRVVAEVQIC-HGKTEAVGQVHIFF 1298
Query: 930 EGGEIELFDGE------VNVKRPMKDETHFEVVESGRYIILLLGKALSVVW-DRHLSISV 982
+ G + L + + V P + V + +L+ KA VW + ++V
Sbjct: 1299 QDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDGSLLVRQKAGVQVWLGANGKVAV 1358
Query: 983 VLKQTYQEKVCGLCGNFDGIQNND 1006
++ + K+CG CGNFDG Q ND
Sbjct: 1359 IVSNDHAGKLCGACGNFDGDQTND 1382
Score = 32.0 bits (71), Expect = 8.8
Identities = 49/178 (27%), Positives = 62/178 (34%), Gaps = 40/178 (22%)
Query: 2494 CLPSACEVVTGSPRG------DSQSSWKSVGSQ---WASPENPCLINECVRVKEEVFIQQ 2544
CL AC+V G P G ++ ++ G+Q W P+ C + E+
Sbjct: 694 CLLDACQV-QGHPGGLCPAVATYVAACQAAGAQLGEWRRPDF-CPLQCPAHSHYELCGDS 751
Query: 2545 RNVSCPQLEVP-----------VCPSGFQLSCKTSACCPSCRCERMEACMLNGTVIGPGK 2593
VSCP L P VC +GF LS T C C G V PG
Sbjct: 752 CPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGP 811
Query: 2594 TVMIDVCTTCRC------MVQVGVISGFKLECRKTTCNPCPLGYKEENNTGECCGRCL 2645
+ C C Q G G ECR G + + TG CGRCL
Sbjct: 812 ----ECERRCECGPGGHVTCQEGAACGPHEECRLED------GVQACHATG--CGRCL 857
>gi|16554449 zonadhesin isoform 3 [Homo sapiens]
Length = 2812
Score = 290 bits (743), Expect = 1e-77
Identities = 222/801 (27%), Positives = 329/801 (41%), Gaps = 88/801 (10%)
Query: 25 GTRGRSSTARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRS---FSIIG----DFQ 77
G + TA C ++G TFDG + F G C+Y+LA C + F + Q
Sbjct: 1146 GCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQ 1205
Query: 78 NGKRVSLSVYLGEFFDIHLFVNGTVTQ-GDQRVSMP-YASKGLYLETEAGYYKLSGEAYG 135
G VY+ + G T G Q+V++P SKG++L + +L E +G
Sbjct: 1206 EGVSCLSKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTE-FG 1264
Query: 136 FVARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSS 195
R DG V +S Y K CGLCGN++ +++D + +G+ D + NSW
Sbjct: 1265 LRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQ 1324
Query: 196 GE-QWCERASPPSS-SCNISSGEMQKGLWEQCQLLKSTSVFARCHPLVDPEPFVALCEKT 253
E Q C++ +S SC+ S G +L+ + F C V F C
Sbjct: 1325 DEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLD 1384
Query: 254 LCECAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCARTCQ 313
+C G C + TC G + W + C CP +Y C PC TC
Sbjct: 1385 MCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCH 1444
Query: 314 SLHINEMCQERCVDGCSCPEGQLLDEGLCVESTECPCVHS-------GKR-YPPGTSLSR 365
S C +RCV+ C C G +L C+ ++C C+H G+R Y PG
Sbjct: 1445 SGFSGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCK--- 1501
Query: 366 DCNTCICRNSQ------WICSNEECPGE--------------CLVTGQSHFKSFDNRYFT 405
C+C ++ W C +E G+ C +G H+ +FD
Sbjct: 1502 --ELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHH 1559
Query: 406 FSGICQYLLARDC----QDHSFSIVIETVQCADDRDAVCTRSVTVRLPGLHNSLVKLKHG 461
F G C Y+L R C QD F + + ++V V + L SL++ G
Sbjct: 1560 FMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLR---G 1616
Query: 462 AGVAMDGQDVQLPLLKGDLRIQHTVTASVRLSYGE-DLQMDWDGRGRLLVKLSPVYAGKT 520
V ++G V LP+ R+ +++++ L Y LQ+ +DG + V + Y G+
Sbjct: 1617 CKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQL 1676
Query: 521 CGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWKLHGDCQD---LQKQHSDPCALNPRMT 577
CGLCGNYN N DD L P G AWKL + L C N
Sbjct: 1677 CGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKPSSCQENSMAD 1736
Query: 578 RFSEEACAVLTSP--TFEACHRAVSPLPYLRNCRYDVCSCSDGRECLCGALASYAAACAG 635
+++ CA+L +P F CH+ V P +C + C LC +L +YA+ CA
Sbjct: 1737 AWNKN-CAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQ 1795
Query: 636 RGVRVAWREPGRCELNCPKGQVYLQCGTPCNLTCRSLSYPDEECNEA--CLEGCFCPPGL 693
G AWR C + CP G Y C +PC TC S++ P +C +A C E C C G
Sbjct: 1796 AGQAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNP-RDCPKALPCAESCECQKG- 1853
Query: 694 YMDERGDCVPKAQCPCYYDGEIFQP--EDIFSDH-----------------------HTM 728
++ CVP QC C + P E ++++ + +
Sbjct: 1854 HILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQI 1913
Query: 729 CYCEDGFMHCTMSGVPGSLLP 749
C+ DG + C SGV LP
Sbjct: 1914 CWALDGLLRCRASGVGVCQLP 1934
Score = 263 bits (673), Expect = 1e-69
Identities = 210/777 (27%), Positives = 324/777 (41%), Gaps = 86/777 (11%)
Query: 33 ARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRS------FSIIGDFQNG------- 79
A C+ G TFDG+++ F G C+Y+L C RS S + + G
Sbjct: 1540 ATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYI 1599
Query: 80 KRVSLSVYLGEFFDIHLFVNGTVTQGDQRVSMP-YASKGLYLETEAGYYKLSGEAYGFVA 138
K V ++V+ I L V RV++P + ++G + L +G
Sbjct: 1600 KAVHVTVF---DLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQV 1656
Query: 139 RIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWAL-SSGE 197
R DGS +V + Y + CGLCGN+N + DD + + L D +W L S E
Sbjct: 1657 RYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSE 1716
Query: 198 QWCERASPPSSSCNISSGEMQKGLWEQCQLL-KSTSVFARCHPLVDPEPFVALCEKTLCE 256
C SSC +S M + C +L F++CH +V P+ A C C
Sbjct: 1717 PGCFLVGGKPSSCQENS--MADAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCG 1774
Query: 257 CAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCARTCQSLH 316
G C +L YA CAQ G W + + C CP G Y C SPC TC S++
Sbjct: 1775 TKGDTTALCRSLQAYASLCAQAGQAP-AWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSIN 1833
Query: 317 INEMCQER--CVDGCSCPEGQLLDEGLCVESTECPCVHS-------GKRYPPGTSLSRDC 367
C + C + C C +G +L CV +C C G+R+ + +R C
Sbjct: 1834 NPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLC 1893
Query: 368 NTCICRNS----QWICS-NEEC-------------PGECLVTGQSHFKSFDNRYFTFSGI 409
TC N+ Q C N+ C G C + G+SH+ SFD +
Sbjct: 1894 -TCSVHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDA 1952
Query: 410 CQYLLARDCQDHSFSIVIETVQCADDRDAVCTRSVTVR--LPGLHNSLVKLKHGAGVAMD 467
C +L + C + ++ + +++ T + + ++++ V L+ G V ++
Sbjct: 1953 CTLVLVKVCHP-AMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQKGHRVLIN 2011
Query: 468 GQDVQLPLLK---GDLRIQHTVTASVRLSYGEDLQMDWDGRGRLLVKLSPVYAGKTCGLC 524
+ V LP + G ++ + V + G +Q+ +DG L +++ Y GK CG+C
Sbjct: 2012 SKQVTLPAISQIPGVSVKSSSIYSIVNIKIG--VQVKFDGNHLLEIEIPTTYYGKVCGMC 2069
Query: 525 GNYNGNQGDDFLTPSGLAEPRVEDFGNAWK---LHGDCQDL-----------QKQHSDPC 570
GN+N + D+ + PS +F N+WK + CQ L Q+ S C
Sbjct: 2070 GNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNC 2129
Query: 571 ALNPRMTRFSEEACAVLTSPTFEACHRAVSPLPYLRNCRYDVCSCSDGRECLCGALASYA 630
+ R E+ A L +P + C + P+L +C +C + LC AL ++
Sbjct: 2130 RAAD-LRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFGGLYQALCQALQAFG 2188
Query: 631 AACAGRGVR-VAWREPGRCELNCPKGQVYLQCGTPCNLTCRSLSYPDEECN-----EACL 684
A C +G++ WR C L CP Y C C+ +C L D C AC
Sbjct: 2189 ATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDL---DGRCEGAKVPSACA 2245
Query: 685 EGCFCPPGLYMDERGDCVPKAQCPC--YYDGEIFQPEDIFSDHHT-MCYCEDGFMHC 738
EGC C PG + E CVP++QC C + G I + S T C C G + C
Sbjct: 2246 EGCICQPGYVLSE-DKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGAIQC 2301
Score = 214 bits (546), Expect = 7e-55
Identities = 197/830 (23%), Positives = 323/830 (38%), Gaps = 141/830 (16%)
Query: 30 SSTARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRS----FSIIGDFQNGKRVSLS 85
S C L G +FDGS +S C+ +L C F I + + + +
Sbjct: 1926 SGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEA 1985
Query: 86 VYLGE-FFDIH-----LFVNGTVTQGDQRVSMPYASK--GLYLETEAGYYKLSGEAYGFV 137
L E + DI+ L V ++V++P S+ G+ +++ + Y + G
Sbjct: 1986 FRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSS-IYSIVNIKIGVQ 2044
Query: 138 ARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGE 197
+ DG+ ++ + Y+ K CG+CGNFN ED+ M + + +F NSW +
Sbjct: 2045 VKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDID 2104
Query: 198 QWC------------ERASPPSSSCNISSGEMQKGLWEQCQLLKSTSVFARCHPLVDPEP 245
C E+ PS +C + + E+C+ V+A+C +D P
Sbjct: 2105 PSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAR---EKCEAALRAPVWAQCASRIDLTP 2161
Query: 246 FVALCEKTLCECAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCV 305
F+ C TLCE G + C AL + TC +G+ W + S C CPA Y C+
Sbjct: 2162 FLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCL 2221
Query: 306 SPCARTCQSLHINEMCQ-----ERCVDGCSCPEGQLLDEGLCVESTECPCVHS-GKRYPP 359
C+ +C L + C+ C +GC C G +L E CV ++C C + G P
Sbjct: 2222 PSCSPSCWDL--DGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPL 2279
Query: 360 GTS-LSRDC-NTCICRNSQWICSNEECPG---------------------ECLVTGQSHF 396
G S +S C C+C C + CP +C V G +
Sbjct: 2280 GKSWVSSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRY 2339
Query: 397 KSFDNRYFTFSGICQYLLARDCQ---DHSFSIVIETVQCAD-DRDAVCTRSVTVRLPGLH 452
+FD + G Y+L + + +++E D R ++ + V + G
Sbjct: 2340 LTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYK 2399
Query: 453 NSLVKLKHGAGVAMDGQDVQLPLLKGDLRIQHTVTASVRLSYGEDLQMDWDGRGRLLVKL 512
V+L+ G + ++ Q + +P + + L +L + + GR ++ L
Sbjct: 2400 ---VQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISL 2456
Query: 513 SPVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWKLHGDCQDLQKQHSDPC-- 570
+Y G GLCGNY+ N+ +D + PSG + FGN+W++ + L+ + P
Sbjct: 2457 PSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEE 2516
Query: 571 -----------------ALNPRMTRFSEEACAVLTSP--TFEACHRAVSPLPYLRNCRYD 611
++ S +AC VL P F ACH+ V+P P+ +C D
Sbjct: 2517 EGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLD 2576
Query: 612 VCSCSDGR---ECLCGALASYAAAC-------------------AGRGVR---------- 639
+CS D R E C L+ + + RG+R
Sbjct: 2577 LCSAQDPREQEELRCQVLSGHGVSSRYHISELYDTLPSILCQPGRPRGLRGPLRGRLRQH 2636
Query: 640 ----VAWR-EPGRCELNCPKGQVYLQCGT-----PCNLTCRSLSYPDEECNE-ACLEGCF 688
+ W EP + C +Y Q G+ C+ C S C +C G
Sbjct: 2637 PRLCLQWHPEPPLADCGCTSNGIYYQLGSSFLTEDCSQRCTCASSRILLCEPFSCRAGEV 2696
Query: 689 CPPGLYMDERGDCVPKAQC---PCYYDGEIFQPEDIFSDHHTMCYCEDGF 735
C G + C P++ C PC DG+ + F+ C CE G+
Sbjct: 2697 CTLG---NHTQGCFPESPCLQNPCQNDGQCREQGATFT-----CECEVGY 2738
Score = 208 bits (529), Expect = 7e-53
Identities = 145/507 (28%), Positives = 211/507 (41%), Gaps = 47/507 (9%)
Query: 239 PLVDPEPFVALCEKTLCECAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAG 298
P + E AL A GL A + +A + ++L T + + CP
Sbjct: 990 PTIPTEKLTALRPPHPSPTATGL--AALVMSPHAPSTPMTSVILGTTTTSRSSTERCPPN 1047
Query: 299 MEYRQCVSPCARTCQSLHINEMCQERCVDGCSCPEGQLLDEGLCVESTECPCVHSGKRYP 358
Y C C +C+S + C C +GC C G L + C++++ C C ++ Y
Sbjct: 1048 ARYESCA--CPASCKSPRPS--CGPLCREGCVCNPGFLFSDNHCIQASSCNCFYNNDYYE 1103
Query: 359 PGTS-LSRDCN----------------------TCICRNSQWICSNEECPGECLVTGQSH 395
PG S +C C +N Q+ C CLV G H
Sbjct: 1104 PGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGDPH 1163
Query: 396 FKSFDNRYFTFSGICQYLLARDC---QDHSFSIVIETVQCADDRDAVCTRSVTVRLPGLH 452
+ +FD R+F F G C Y+LA+ C D F + + + + C V V LP
Sbjct: 1164 YVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQE-GVSCLSKVYVTLP--- 1219
Query: 453 NSLVKLKHGAGVAMDGQDVQLPLLKGDLRIQHTVTASVRLSYGEDLQMDWDGRGRLLVKL 512
S V L G + GQ V LP + V L L++ WDG +L V +
Sbjct: 1220 ESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDGDQQLYVTV 1279
Query: 513 SPVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWKLHGD----CQDLQKQHSD 568
S Y+GK CGLCGNY+GN +D L G E+ GN+W+ D CQ Q +S
Sbjct: 1280 SSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSP 1339
Query: 569 PCALNPRMTRFSEEACAVL--TSPTFEACHRAVSPLPYLRNCRYDVCSCSDGRECLCGAL 626
C + + + C L T FE C V + +C D+C + LC +
Sbjct: 1340 SCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHM 1399
Query: 627 ASYAAAC--AGRGVRVAWREPGRCELNCPKGQVYLQCGTPCNLTCRSLSYPDEECNEACL 684
++ C AG V+ WREP C + CP Y C PC TC S + C++ C+
Sbjct: 1400 STMTTTCQDAGHAVK-PWREPHFCPMACPPNSKYSLCAKPCPDTCHS-GFSGMFCSDRCV 1457
Query: 685 EGCFCPPGLYMDERGDCVPKAQCPCYY 711
E C C PG + +C+P++QC C +
Sbjct: 1458 EACECNPGFVLSGL-ECIPRSQCGCLH 1483
Score = 175 bits (444), Expect = 5e-43
Identities = 125/470 (26%), Positives = 189/470 (40%), Gaps = 53/470 (11%)
Query: 776 CPADNLRAEGLECTKTCQNYDLECMSMGCVSGCLCPPGMVRHENRCVALERCPCFHQGKE 835
CP N R E C +C++ C + C GC+C PG + +N C+ C CF+
Sbjct: 1044 CPP-NARYESCACPASCKSPRPSCGPL-CREGCVCNPGFLFSDNHCIQASSCNCFYNNDY 1101
Query: 836 YAPG----------------------ETVKIGCNT-CVCRDRKWNCTDHVCDATCSTIGM 872
Y PG + + G +T C ++ ++ C + ATC G
Sbjct: 1102 YEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGD 1161
Query: 873 AHYLTFDGLKYLFPGECQYVLVQDYCGSNPGTFRILVGNKGCSHPSVKCKKRVTILVEGG 932
HY+TFDG + F G+C Y+L Q S FR+ N+ V C +V + +
Sbjct: 1162 PHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEGVSCLSKVYVTLPES 1221
Query: 933 EIELFDGE------VNVKRPMKDETHFEVVESGRYIILLLGKALSVVWDRHLSISVVLKQ 986
+ L G V P + SGR++ L L V WD + V +
Sbjct: 1222 TVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDGDQQLYVTVSS 1281
Query: 987 TYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKV-SSQCADTRKVPLDSSPAT 1045
TY K+CGLCGN+DG +ND + D + GNSW+ + + +K + +SP +
Sbjct: 1282 TYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSP-S 1340
Query: 1046 CHNNIMKQTMVDSSCRIL--TSDVFQDCNKLVDPEPYLDVCIYDTCSCESIGDCACFCDT 1103
C +++ C L T F+ C V + D C+ D C + + C
Sbjct: 1341 CDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQGLQH--LLCTH 1398
Query: 1104 IAAYAHVCAQHGKVV-TWRTATLCPQSCEERNLRENGYECEWRYNSCAPACQVTCQHP-E 1161
++ C G V WR CP +C + +Y+ CA C TC
Sbjct: 1399 MSTMTTTCQDAGHAVKPWREPHFCPMACPPNS----------KYSLCAKPCPDTCHSGFS 1448
Query: 1162 PLACPVQCVEGCHAHCPPGKILDELLQTCVDPEDCPVCEVAGRRFASGKK 1211
+ C +CVE C C PG +L L C+ C AG F G++
Sbjct: 1449 GMFCSDRCVEAC--ECNPGFVLSGL--ECIPRSQCGCLHPAGSYFKVGER 1494
Score = 150 bits (378), Expect = 2e-35
Identities = 130/515 (25%), Positives = 209/515 (40%), Gaps = 79/515 (15%)
Query: 769 PPMVKLVCPADNLRAEGLE-CTKTCQN-YDLECMSMGCVSGCLCPPGMVRHENRCVALER 826
P + CP ++ + + C TC + + S CV C C PG V C+ +
Sbjct: 1419 PHFCPMACPPNSKYSLCAKPCPDTCHSGFSGMFCSDRCVEACECNPGFVLSGLECIPRSQ 1478
Query: 827 CPCFHQ-GKEYAPGET-VKIGCNT-CVC------RDRKWNC-TDHVCD------------ 864
C C H G + GE K GC CVC R + W C C
Sbjct: 1479 CGCLHPAGSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQG 1538
Query: 865 -ATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPGTFRILVGNKGCSHPSVKCKK 923
ATC+ G HYLTFDG + F G C YVL + + ++ ++ S +
Sbjct: 1539 AATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVV---------SATNEN 1589
Query: 924 RVTIL----VEGGEIELFDGEVNVKRPMK--------------DETHFEVVESGRYIILL 965
R IL ++ + +FD +++ R K + + S ++L
Sbjct: 1590 RGGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLY 1649
Query: 966 LGKALSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSW 1025
L V +D + V + +Y ++CGLCGN++ +D + ++ D + G +W
Sbjct: 1650 TNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAW 1709
Query: 1026 KVSSQCADTRKVPLDSSPATCHNNIMKQTMVDSSCRILTSDV--FQDCNKLVDPEPYLDV 1083
K+ + ++ + P++C N M + +C IL + F C+++V P+
Sbjct: 1710 KLP-ESSEPGCFLVGGKPSSCQENSMADAW-NKNCAILINPQGPFSQCHQVVPPQSSFAS 1767
Query: 1084 CIYDTCSCESIGDCACFCDTIAAYAHVCAQHGKVVTWRTATLCPQSCEERNLRENGYECE 1143
C++ C + GD C ++ AYA +CAQ G+ WR T CP C +
Sbjct: 1768 CVHGQCGTK--GDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRCPPGS--------- 1816
Query: 1144 WRYNSCAPACQVTCQH-PEPLACP--VQCVEGCHAHCPPGKILDELLQTCVDPEDCPVCE 1200
Y+ C+ C TC P CP + C E C C G IL +CV C +
Sbjct: 1817 -SYSPCSSPCPDTCSSINNPRDCPKALPCAESC--ECQKGHILSG--TSCVPLGQCGCTD 1871
Query: 1201 VAGRRFASGKKVTLNPSDPEHCQICHCDV-VNLTC 1234
AG G++ ++ ++C C V N+TC
Sbjct: 1872 PAGSYHPVGERWY---TENTCTRLCTCSVHNNITC 1903
Score = 127 bits (320), Expect = 1e-28
Identities = 105/445 (23%), Positives = 176/445 (39%), Gaps = 44/445 (9%)
Query: 1879 CMDEDGNEKRPGDVWTLPDQCHTVTCQPDGQTLLKSHRVNCDRGLRPSCPNSQSPVKVEE 1938
C+ G+ + G+ W P C+ ++R+ C C + + +
Sbjct: 1481 CLHPAGSYFKVGERWYKPGCKELCVCE-------SNNRIRCQPW---RCRAQEFCGQQDG 1530
Query: 1939 TCGCRWTCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQ---NKEQDLEVILHNGACSP 1995
GC CT S H +TFDG G+C+YVL + ++ QD ++ +
Sbjct: 1531 IYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENR 1590
Query: 1996 GA--RQGCMKSIEVKHSALSVELHSDMEVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFN 2053
G +K++ V LS+ L +V +NG V++P V + + + +
Sbjct: 1591 GGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYT 1650
Query: 2054 HLGHIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQE 2113
+ G + + P ++ + GLCG + N +D + D + D L
Sbjct: 1651 NFGLQVRY--DGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAA 1708
Query: 2114 WTV---QRPG--------QTCQPILEEQCLVPDSSHCQVLLLPL--FAECHKVLAPATFY 2160
W + PG +CQ E + +C +L+ P F++CH+V+ P + +
Sbjct: 1709 WKLPESSEPGCFLVGGKPSSCQ---ENSMADAWNKNCAILINPQGPFSQCHQVVPPQSSF 1765
Query: 2161 AICQQDSCHQE----QVCEVIASYAHLCRTNGVCVDWRTPDFCAMSCPPSLVYNHCEHGC 2216
A C C + +C + +YA LC G WR FC M CPP Y+ C C
Sbjct: 1766 ASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRCPPGSSYSPCSSPC 1825
Query: 2217 PRHCDGNVSSCGDHP-----SEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAW 2271
P C ++++ D P +E C C ++ SCVP C C G H E W
Sbjct: 1826 PDTC-SSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQC-GCTDPAGSYHPVGERW 1883
Query: 2272 VPDHQPCQICTCLSGRKVNCTTQPC 2296
++ ++CTC + C C
Sbjct: 1884 YTENTCTRLCTCSVHNNITCFQSTC 1908
Score = 115 bits (288), Expect = 6e-25
Identities = 116/446 (26%), Positives = 161/446 (36%), Gaps = 68/446 (15%)
Query: 1889 PGDVWTLPDQCHTVTCQPDGQTLLKSHRVNCDR---GLRPSCPNSQSPVKVEETCGCRWT 1945
PG W P+ C P RV C G C G T
Sbjct: 1104 PGAEWFSPNCTEHCRCWPGS-------RVECQISQCGTHTVCQLKNGQYGCHPYAG---T 1153
Query: 1946 CPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKEQDLEVILHNGACSPGARQ---GCM 2002
C+ G H VTFDG++F G C+Y+L Q + A + Q C+
Sbjct: 1154 ATCLVYGDP--HYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEGVSCL 1211
Query: 2003 KSIEVKHSALSVELHSDMEVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHLGHIFTFT 2062
+ V +V L V G+ V++P + V+ LG F
Sbjct: 1212 SKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSK---GVF-----------LGASGRFV 1257
Query: 2063 PQNNEFQLQLS-----------PKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLV 2111
EF L++ T++ K GLCG D N ND + DG+ D + L
Sbjct: 1258 ELQTEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELG 1317
Query: 2112 QEW-TVQRPGQTCQPILEEQCLVPDSSHCQVLLLPLFA-----------ECHKVLAPATF 2159
W T Q Q CQ DSS + P F C + A+F
Sbjct: 1318 NSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASF 1377
Query: 2160 YAICQQDSCH----QEQVCEVIASYAHLCRTNGVCVD-WRTPDFCAMSCPPSLVYNHCEH 2214
+ C D C Q +C +++ C+ G V WR P FC M+CPP+ Y+ C
Sbjct: 1378 FDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAK 1437
Query: 2215 GCPRHCDGNVSS--CGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWV 2272
CP C S C D E C C P V+ C+P C C+ G + E W
Sbjct: 1438 PCPDTCHSGFSGMFCSDRCVEACECNPGFVLSGLECIPRSQC-GCLHPAGSYFKVGERW- 1495
Query: 2273 PDHQP-C-QICTCLSGRKVNCTTQPC 2296
++P C ++C C S ++ C C
Sbjct: 1496 --YKPGCKELCVCESNNRIRCQPWRC 1519
Score = 115 bits (288), Expect = 6e-25
Identities = 137/565 (24%), Positives = 206/565 (36%), Gaps = 82/565 (14%)
Query: 763 RSLSCRPPMVK------LVCPADNLRAEGL-ECTKTCQNYDLEC----MSMGCVSGCLCP 811
+S +PP+ + L CPA + L C+ +C + D C + C GC+C
Sbjct: 2192 QSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEGCICQ 2251
Query: 812 PGMVRHENRCVALERCPC--FHQGKEYAPGETVKIGCNT-CVCRDRKWNCTDHVCDA--- 865
PG V E++CV +C C H G V GC CVC C D C +
Sbjct: 2252 PGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGAIQCGDFRCPSGSH 2311
Query: 866 ------------------TCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPGTFRI 907
CS G YLTFDG Y G YVL++ G +
Sbjct: 2312 CQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPL 2371
Query: 908 LVGNKGCSHP--SVKCKKRVTILVEGGEIELFDG---EVNVKR---PMKDETHFEVVESG 959
LV + P S + V V G +++L G VN ++ P + H V G
Sbjct: 2372 LVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWG 2431
Query: 960 RYIILLLGKALSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPV 1019
+ + L+ L V + + + L Y+ V GLCGN+D + ND+ + + ++
Sbjct: 2432 QRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLN 2491
Query: 1020 DFGNSWKVSSQCA---DTRKVPLDSSPATCHNNIMKQTMVD------------SSCRILT 1064
FGNSW+V ++ A R +P + + V +CR+L
Sbjct: 2492 TFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLA 2551
Query: 1065 --SDVFQDCNKLVDPEPYLDVCIYDTCSCESIGDC-ACFCDTIAAYAHVCAQHGKVVTWR 1121
F C++ V PEP+ + C+ D CS + + C ++ + H +
Sbjct: 2552 DPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGHGVSSRYHISELYDT 2611
Query: 1122 TATLCPQSCEERNLRENGYECEWRYNSCAPACQVTCQHPEPLACPVQCV-EGCHAHCPPG 1180
++ Q R LR R C HPEP C G +
Sbjct: 2612 LPSILCQPGRPRGLRG---PLRGRLRQHPRLC--LQWHPEPPLADCGCTSNGIYYQLGSS 2666
Query: 1181 KILDELLQTCV---------DPEDCPVCEVAGRRFASGKKVTLNPSDPEHCQ---ICHCD 1228
+ ++ Q C +P C EV + +P CQ C
Sbjct: 2667 FLTEDCSQRCTCASSRILLCEPFSCRAGEVCTLGNHTQGCFPESPCLQNPCQNDGQCREQ 2726
Query: 1229 VVNLTCEACQ--EPGGLVVPPTDAP 1251
TCE C+ GGL + P DAP
Sbjct: 2727 GATFTCE-CEVGYGGGLCMEPRDAP 2750
Score = 110 bits (276), Expect = 1e-23
Identities = 112/487 (22%), Positives = 172/487 (35%), Gaps = 94/487 (19%)
Query: 788 CTKTCQ--NYDLEC-MSMGCVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAP-GE--- 840
C TC N +C ++ C C C G + CV L +C C Y P GE
Sbjct: 1825 CPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWY 1884
Query: 841 TVKIGCNTCVCR-DRKWNCTDHVCD-------------------ATCSTIGMAHYLTFDG 880
T C C C C C G +HY++FDG
Sbjct: 1885 TENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDG 1944
Query: 881 LKYLFPGECQYVLVQDYCGSNPGTFRILVGNKGCSHPSVKCKKRVTILVEGGE------- 933
+ P C VLV+ V + + P K + G E
Sbjct: 1945 SNHSIPDACTLVLVK-------------VCHPAMALPFFKISAKHEKEEGGTEAFRLHEV 1991
Query: 934 -IELFDGEVNVKR--------------PMKDETHFEVVESGRYIILLLGKALSVVWDRHL 978
I+++D +V +++ + V S Y I+ + + V +D +
Sbjct: 1992 YIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNH 2051
Query: 979 SISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWK-------VSSQC 1031
+ + + TY KVCG+CGNF+ + ++L + +V +F NSWK S
Sbjct: 2052 LLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLL 2111
Query: 1032 ADTRKVPL---DSSPATCHNNIMKQTMVDSSCRILTSDVFQDCNKLVDPEPYLDVCIYDT 1088
D +++P ++ C +++ + L + V+ C +D P+L C
Sbjct: 2112 VDEQQIPAEQQENPSGNCRAADLRRAR-EKCEAALRAPVWAQCASRIDLTPFLVDCA--N 2168
Query: 1089 CSCESIGDCACFCDTIAAYAHVCAQHG-KVVTWRTATLCPQSCEERNLRENGYECEWRYN 1147
CE G C + A+ C G K WR ++ CP C + Y
Sbjct: 2169 TLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYS----------SYT 2218
Query: 1148 SCAPACQVTC----QHPEPLACPVQCVEGCHAHCPPGKILDELLQTCVDPEDCPVCEVAG 1203
+C P+C +C E P C EGC C PG +L E CV C + G
Sbjct: 2219 NCLPSCSPSCWDLDGRCEGAKVPSACAEGC--ICQPGYVLSE--DKCVPRSQCGCKDAHG 2274
Query: 1204 RRFASGK 1210
GK
Sbjct: 2275 GSIPLGK 2281
Score = 103 bits (258), Expect = 2e-21
Identities = 98/458 (21%), Positives = 177/458 (38%), Gaps = 56/458 (12%)
Query: 1879 CMDEDGNEKRPGDVWTLPDQCHTVTCQPDGQTLLKSHRVNCDRGLRPSCPNSQSPVKVEE 1938
C D G+ G+ W + C T C T + + C + +C +Q ++
Sbjct: 1869 CTDPAGSYHPVGERWYTENTC-TRLC-----TCSVHNNITC---FQSTCKPNQICWALDG 1919
Query: 1939 TCGCRWTCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKEQDLEVILHNGACSPGAR 1998
CR + VC H V+FDG N + +C+ VL + + + +
Sbjct: 1920 LLRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKE 1979
Query: 1999 QGCMKSIEVKHSALS-----VELHSDMEVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFN 2053
+G ++ + + V L V +N + V++P + V+V + ++ +
Sbjct: 1980 EGGTEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNI 2039
Query: 2054 HLGHIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQE 2113
+G F N+ ++++ P T+ K G+CG ++ ++ M+ V V
Sbjct: 2040 KIGVQVKFDG-NHLLEIEI-PTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNS 2097
Query: 2114 WTVQRPGQTCQPILEEQCLVP------DSSHCQ-------------VLLLPLFAECHKVL 2154
W + +CQ +L ++ +P S +C+ L P++A+C +
Sbjct: 2098 WKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRI 2157
Query: 2155 APATFYAICQQDSCH----QEQVCEVIASYAHLCRTNGVCVD-WRTPDFCAMSCPPSLVY 2209
F C C + +C+ + ++ C++ G+ WR FC + CP Y
Sbjct: 2158 DLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSY 2217
Query: 2210 NHCEHGCPRHC---DGNV------SSCGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGE 2260
+C C C DG S+C +EGC C P V+ E CVP C C
Sbjct: 2218 TNCLPSCSPSCWDLDGRCEGAKVPSAC----AEGCICQPGYVLSEDKCVPRSQC-GCKDA 2272
Query: 2261 DGVQHQFLEAWVPDHQPCQICTCLSGRKVNCTTQPCPT 2298
G ++WV + C C +G + C CP+
Sbjct: 2273 HGGSIPLGKSWV-SSGCTEKCVC-TGGAIQCGDFRCPS 2308
Score = 88.2 bits (217), Expect = 1e-16
Identities = 112/472 (23%), Positives = 177/472 (37%), Gaps = 87/472 (18%)
Query: 1950 CTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKE---QDLEVILHNGA--CSPGARQGCMKS 2004
C+ +TFDG +++L G +YVL + + + +E +L G P ++
Sbjct: 2331 CSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQE 2390
Query: 2005 IEVKHSALSVELHSDMEVTVNGRLVSVPY-VGGNMEVNVYGAIMHEVRFNHLGHIFTFTP 2063
+ V+L + +E+ VN + ++VPY ++ V ++G ++ V L + +F
Sbjct: 2391 VITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFEL--VVSFGG 2448
Query: 2064 QNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTVQ------ 2117
+ N + L P + GLCG D+N ND ML G +T + T W V+
Sbjct: 2449 RKNAV-ISL-PSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALL 2506
Query: 2118 -------------------RPGQTCQPILEEQCLVPDSSHCQVLLLPL--FAECHKVLAP 2156
R G EQ + C+VL P FA CH+ +AP
Sbjct: 2507 RFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAP 2566
Query: 2157 ATFYAICQQDSCHQEQVCEVIASYAHLCRTNGVCVDWRTPDFCAMSCPPSLVYNHCEHGC 2216
F C D C + E + +GV + + PS++ C+ G
Sbjct: 2567 EPFQEHCVLDLCSAQDPREQEELRCQVLSGHGVSSRYHISEL--YDTLPSIL---CQPGR 2621
Query: 2217 PRHCDGNVSSCGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWVPDHQ 2276
PR G P G ++ L+ P A C +G+ +Q +++ +
Sbjct: 2622 PRGLRG--------PLRGRLRQHPRLCLQWHPEPPLADCGCT-SNGIYYQLGSSFLTE-D 2671
Query: 2277 PCQICTCLSGRKVNCTTQPCPTAKAPTCGLCEVARLRQNADQCCPEYECVCDPVSCDLPP 2336
Q CTC S R + C C EV L + C PE C+ +P
Sbjct: 2672 CSQRCTCASSRILLCEPFSCRAG--------EVCTLGNHTQGCFPESPCLQNP------- 2716
Query: 2337 VPHCERGLQPTLTNPGECR---PNFTCACRKEE----CKRVSPPSCPPHRLP 2381
C+ N G+CR FTC C C + P PP R P
Sbjct: 2717 ---CQ--------NDGQCREQGATFTCECEVGYGGGLC--MEPRDAPPPRKP 2755
Score = 50.4 bits (119), Expect = 2e-05
Identities = 28/96 (29%), Positives = 38/96 (39%), Gaps = 5/96 (5%)
Query: 2203 CPPSLVYNHCEHGCPRHCDGNVSSCGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDG 2262
CPP+ Y C CP C SCG EGC C P + + C+ +C C +
Sbjct: 1044 CPPNARYESC--ACPASCKSPRPSCGPLCREGCVCNPGFLFSDNHCIQASSC-NCFYNND 1100
Query: 2263 VQHQFLEAWVPDHQPCQICTCLSGRKVNCTTQPCPT 2298
E + P+ + C C G +V C C T
Sbjct: 1101 YYEPGAEWFSPN--CTEHCRCWPGSRVECQISQCGT 1134
Score = 49.7 bits (117), Expect = 4e-05
Identities = 27/85 (31%), Positives = 39/85 (45%), Gaps = 8/85 (9%)
Query: 652 CPKGQVYLQCGTPCNLTCRSLSYPDEECNEACLEGCFCPPGLYMDERGDCVPKAQCPCYY 711
CP Y C P + C+S P C C EGC C PG + C+ + C C+Y
Sbjct: 1044 CPPNARYESCACPAS--CKS---PRPSCGPLCREGCVCNPGFLFSDN-HCIQASSCNCFY 1097
Query: 712 DGEIFQP-EDIFSDHHT-MCYCEDG 734
+ + ++P + FS + T C C G
Sbjct: 1098 NNDYYEPGAEWFSPNCTEHCRCWPG 1122
>gi|27881494 zonadhesin isoform 6 [Homo sapiens]
Length = 2721
Score = 290 bits (743), Expect = 1e-77
Identities = 222/801 (27%), Positives = 329/801 (41%), Gaps = 88/801 (10%)
Query: 25 GTRGRSSTARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRS---FSIIG----DFQ 77
G + TA C ++G TFDG + F G C+Y+LA C + F + Q
Sbjct: 1146 GCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQ 1205
Query: 78 NGKRVSLSVYLGEFFDIHLFVNGTVTQ-GDQRVSMP-YASKGLYLETEAGYYKLSGEAYG 135
G VY+ + G T G Q+V++P SKG++L + +L E +G
Sbjct: 1206 EGVSCLSKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTE-FG 1264
Query: 136 FVARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSS 195
R DG V +S Y K CGLCGN++ +++D + +G+ D + NSW
Sbjct: 1265 LRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQ 1324
Query: 196 GE-QWCERASPPSS-SCNISSGEMQKGLWEQCQLLKSTSVFARCHPLVDPEPFVALCEKT 253
E Q C++ +S SC+ S G +L+ + F C V F C
Sbjct: 1325 DEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLD 1384
Query: 254 LCECAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCARTCQ 313
+C G C + TC G + W + C CP +Y C PC TC
Sbjct: 1385 MCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCH 1444
Query: 314 SLHINEMCQERCVDGCSCPEGQLLDEGLCVESTECPCVHS-------GKR-YPPGTSLSR 365
S C +RCV+ C C G +L C+ ++C C+H G+R Y PG
Sbjct: 1445 SGFSGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCK--- 1501
Query: 366 DCNTCICRNSQ------WICSNEECPGE--------------CLVTGQSHFKSFDNRYFT 405
C+C ++ W C +E G+ C +G H+ +FD
Sbjct: 1502 --ELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHH 1559
Query: 406 FSGICQYLLARDC----QDHSFSIVIETVQCADDRDAVCTRSVTVRLPGLHNSLVKLKHG 461
F G C Y+L R C QD F + + ++V V + L SL++ G
Sbjct: 1560 FMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLR---G 1616
Query: 462 AGVAMDGQDVQLPLLKGDLRIQHTVTASVRLSYGE-DLQMDWDGRGRLLVKLSPVYAGKT 520
V ++G V LP+ R+ +++++ L Y LQ+ +DG + V + Y G+
Sbjct: 1617 CKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQL 1676
Query: 521 CGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWKLHGDCQD---LQKQHSDPCALNPRMT 577
CGLCGNYN N DD L P G AWKL + L C N
Sbjct: 1677 CGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKPSSCQENSMAD 1736
Query: 578 RFSEEACAVLTSP--TFEACHRAVSPLPYLRNCRYDVCSCSDGRECLCGALASYAAACAG 635
+++ CA+L +P F CH+ V P +C + C LC +L +YA+ CA
Sbjct: 1737 AWNKN-CAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQ 1795
Query: 636 RGVRVAWREPGRCELNCPKGQVYLQCGTPCNLTCRSLSYPDEECNEA--CLEGCFCPPGL 693
G AWR C + CP G Y C +PC TC S++ P +C +A C E C C G
Sbjct: 1796 AGQAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNP-RDCPKALPCAESCECQKG- 1853
Query: 694 YMDERGDCVPKAQCPCYYDGEIFQP--EDIFSDH-----------------------HTM 728
++ CVP QC C + P E ++++ + +
Sbjct: 1854 HILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQI 1913
Query: 729 CYCEDGFMHCTMSGVPGSLLP 749
C+ DG + C SGV LP
Sbjct: 1914 CWALDGLLRCRASGVGVCQLP 1934
Score = 263 bits (673), Expect = 1e-69
Identities = 210/777 (27%), Positives = 324/777 (41%), Gaps = 86/777 (11%)
Query: 33 ARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRS------FSIIGDFQNG------- 79
A C+ G TFDG+++ F G C+Y+L C RS S + + G
Sbjct: 1540 ATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYI 1599
Query: 80 KRVSLSVYLGEFFDIHLFVNGTVTQGDQRVSMP-YASKGLYLETEAGYYKLSGEAYGFVA 138
K V ++V+ I L V RV++P + ++G + L +G
Sbjct: 1600 KAVHVTVF---DLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQV 1656
Query: 139 RIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWAL-SSGE 197
R DGS +V + Y + CGLCGN+N + DD + + L D +W L S E
Sbjct: 1657 RYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSE 1716
Query: 198 QWCERASPPSSSCNISSGEMQKGLWEQCQLL-KSTSVFARCHPLVDPEPFVALCEKTLCE 256
C SSC +S M + C +L F++CH +V P+ A C C
Sbjct: 1717 PGCFLVGGKPSSCQENS--MADAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCG 1774
Query: 257 CAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCARTCQSLH 316
G C +L YA CAQ G W + + C CP G Y C SPC TC S++
Sbjct: 1775 TKGDTTALCRSLQAYASLCAQAGQAP-AWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSIN 1833
Query: 317 INEMCQER--CVDGCSCPEGQLLDEGLCVESTECPCVHS-------GKRYPPGTSLSRDC 367
C + C + C C +G +L CV +C C G+R+ + +R C
Sbjct: 1834 NPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLC 1893
Query: 368 NTCICRNS----QWICS-NEEC-------------PGECLVTGQSHFKSFDNRYFTFSGI 409
TC N+ Q C N+ C G C + G+SH+ SFD +
Sbjct: 1894 -TCSVHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDA 1952
Query: 410 CQYLLARDCQDHSFSIVIETVQCADDRDAVCTRSVTVR--LPGLHNSLVKLKHGAGVAMD 467
C +L + C + ++ + +++ T + + ++++ V L+ G V ++
Sbjct: 1953 CTLVLVKVCHP-AMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQKGHRVLIN 2011
Query: 468 GQDVQLPLLK---GDLRIQHTVTASVRLSYGEDLQMDWDGRGRLLVKLSPVYAGKTCGLC 524
+ V LP + G ++ + V + G +Q+ +DG L +++ Y GK CG+C
Sbjct: 2012 SKQVTLPAISQIPGVSVKSSSIYSIVNIKIG--VQVKFDGNHLLEIEIPTTYYGKVCGMC 2069
Query: 525 GNYNGNQGDDFLTPSGLAEPRVEDFGNAWK---LHGDCQDL-----------QKQHSDPC 570
GN+N + D+ + PS +F N+WK + CQ L Q+ S C
Sbjct: 2070 GNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNC 2129
Query: 571 ALNPRMTRFSEEACAVLTSPTFEACHRAVSPLPYLRNCRYDVCSCSDGRECLCGALASYA 630
+ R E+ A L +P + C + P+L +C +C + LC AL ++
Sbjct: 2130 RAAD-LRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFGGLYQALCQALQAFG 2188
Query: 631 AACAGRGVRVA-WREPGRCELNCPKGQVYLQCGTPCNLTCRSLSYPDEECN-----EACL 684
A C +G++ WR C L CP Y C C+ +C L D C AC
Sbjct: 2189 ATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDL---DGRCEGAKVPSACA 2245
Query: 685 EGCFCPPGLYMDERGDCVPKAQCPC--YYDGEIFQPEDIFSDHHT-MCYCEDGFMHC 738
EGC C PG + E CVP++QC C + G I + S T C C G + C
Sbjct: 2246 EGCICQPGYVLSE-DKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGAIQC 2301
Score = 220 bits (561), Expect = 1e-56
Identities = 177/705 (25%), Positives = 289/705 (40%), Gaps = 91/705 (12%)
Query: 30 SSTARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRS----FSIIGDFQNGKRVSLS 85
S C L G +FDGS +S C+ +L C F I + + + +
Sbjct: 1926 SGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEA 1985
Query: 86 VYLGE-FFDIH-----LFVNGTVTQGDQRVSMPYASK--GLYLETEAGYYKLSGEAYGFV 137
L E + DI+ L V ++V++P S+ G+ +++ + Y + G
Sbjct: 1986 FRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSS-IYSIVNIKIGVQ 2044
Query: 138 ARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGE 197
+ DG+ ++ + Y+ K CG+CGNFN ED+ M + + +F NSW +
Sbjct: 2045 VKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDID 2104
Query: 198 QWC------------ERASPPSSSCNISSGEMQKGLWEQCQLLKSTSVFARCHPLVDPEP 245
C E+ PS +C + + E+C+ V+A+C +D P
Sbjct: 2105 PSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAR---EKCEAALRAPVWAQCASRIDLTP 2161
Query: 246 FVALCEKTLCECAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCV 305
F+ C TLCE G + C AL + TC +G+ W + S C CPA Y C+
Sbjct: 2162 FLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCL 2221
Query: 306 SPCARTCQSLHINEMCQ-----ERCVDGCSCPEGQLLDEGLCVESTECPCVHS-GKRYPP 359
C+ +C L + C+ C +GC C G +L E CV ++C C + G P
Sbjct: 2222 PSCSPSCWDL--DGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPL 2279
Query: 360 GTS-LSRDC-NTCICRNSQWICSNEECPG---------------------ECLVTGQSHF 396
G S +S C C+C C + CP +C V G +
Sbjct: 2280 GKSWVSSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRY 2339
Query: 397 KSFDNRYFTFSGICQYLLARDCQ---DHSFSIVIETVQCAD-DRDAVCTRSVTVRLPGLH 452
+FD + G Y+L + + +++E D R ++ + V + G
Sbjct: 2340 LTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYK 2399
Query: 453 NSLVKLKHGAGVAMDGQDVQLPLLKGDLRIQHTVTASVRLSYGEDLQMDWDGRGRLLVKL 512
V+L+ G + ++ Q + +P + + L +L + + GR ++ L
Sbjct: 2400 ---VQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISL 2456
Query: 513 SPVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWKLHGDCQDLQKQHSDPC-- 570
+Y G GLCGNY+ N+ +D + PSG + FGN+W++ + L+ + P
Sbjct: 2457 PSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEE 2516
Query: 571 -----------------ALNPRMTRFSEEACAVLTSP--TFEACHRAVSPLPYLRNCRYD 611
++ S +AC VL P F ACH+ V+P P+ +C D
Sbjct: 2517 EGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLD 2576
Query: 612 VCSCSDGR---ECLCGALASYAAACAGRGVRVA-WREPGRCELNC 652
+CS D R E C L+ YA C G +A WR+ CE C
Sbjct: 2577 LCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCESPC 2621
Score = 208 bits (529), Expect = 7e-53
Identities = 145/507 (28%), Positives = 211/507 (41%), Gaps = 47/507 (9%)
Query: 239 PLVDPEPFVALCEKTLCECAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAG 298
P + E AL A GL A + +A + ++L T + + CP
Sbjct: 990 PTIPTEKLTALRPPHPSPTATGL--AALVMSPHAPSTPMTSVILGTTTTSRSSTERCPPN 1047
Query: 299 MEYRQCVSPCARTCQSLHINEMCQERCVDGCSCPEGQLLDEGLCVESTECPCVHSGKRYP 358
Y C C +C+S + C C +GC C G L + C++++ C C ++ Y
Sbjct: 1048 ARYESCA--CPASCKSPRPS--CGPLCREGCVCNPGFLFSDNHCIQASSCNCFYNNDYYE 1103
Query: 359 PGTS-LSRDCN----------------------TCICRNSQWICSNEECPGECLVTGQSH 395
PG S +C C +N Q+ C CLV G H
Sbjct: 1104 PGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGDPH 1163
Query: 396 FKSFDNRYFTFSGICQYLLARDC---QDHSFSIVIETVQCADDRDAVCTRSVTVRLPGLH 452
+ +FD R+F F G C Y+LA+ C D F + + + + C V V LP
Sbjct: 1164 YVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQE-GVSCLSKVYVTLP--- 1219
Query: 453 NSLVKLKHGAGVAMDGQDVQLPLLKGDLRIQHTVTASVRLSYGEDLQMDWDGRGRLLVKL 512
S V L G + GQ V LP + V L L++ WDG +L V +
Sbjct: 1220 ESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDGDQQLYVTV 1279
Query: 513 SPVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWKLHGD----CQDLQKQHSD 568
S Y+GK CGLCGNY+GN +D L G E+ GN+W+ D CQ Q +S
Sbjct: 1280 SSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSP 1339
Query: 569 PCALNPRMTRFSEEACAVL--TSPTFEACHRAVSPLPYLRNCRYDVCSCSDGRECLCGAL 626
C + + + C L T FE C V + +C D+C + LC +
Sbjct: 1340 SCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHM 1399
Query: 627 ASYAAAC--AGRGVRVAWREPGRCELNCPKGQVYLQCGTPCNLTCRSLSYPDEECNEACL 684
++ C AG V+ WREP C + CP Y C PC TC S + C++ C+
Sbjct: 1400 STMTTTCQDAGHAVK-PWREPHFCPMACPPNSKYSLCAKPCPDTCHS-GFSGMFCSDRCV 1457
Query: 685 EGCFCPPGLYMDERGDCVPKAQCPCYY 711
E C C PG + +C+P++QC C +
Sbjct: 1458 EACECNPGFVLSGL-ECIPRSQCGCLH 1483
Score = 175 bits (444), Expect = 5e-43
Identities = 125/470 (26%), Positives = 189/470 (40%), Gaps = 53/470 (11%)
Query: 776 CPADNLRAEGLECTKTCQNYDLECMSMGCVSGCLCPPGMVRHENRCVALERCPCFHQGKE 835
CP N R E C +C++ C + C GC+C PG + +N C+ C CF+
Sbjct: 1044 CPP-NARYESCACPASCKSPRPSCGPL-CREGCVCNPGFLFSDNHCIQASSCNCFYNNDY 1101
Query: 836 YAPG----------------------ETVKIGCNT-CVCRDRKWNCTDHVCDATCSTIGM 872
Y PG + + G +T C ++ ++ C + ATC G
Sbjct: 1102 YEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGD 1161
Query: 873 AHYLTFDGLKYLFPGECQYVLVQDYCGSNPGTFRILVGNKGCSHPSVKCKKRVTILVEGG 932
HY+TFDG + F G+C Y+L Q S FR+ N+ V C +V + +
Sbjct: 1162 PHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEGVSCLSKVYVTLPES 1221
Query: 933 EIELFDGE------VNVKRPMKDETHFEVVESGRYIILLLGKALSVVWDRHLSISVVLKQ 986
+ L G V P + SGR++ L L V WD + V +
Sbjct: 1222 TVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDGDQQLYVTVSS 1281
Query: 987 TYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKV-SSQCADTRKVPLDSSPAT 1045
TY K+CGLCGN+DG +ND + D + GNSW+ + + +K + +SP +
Sbjct: 1282 TYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSP-S 1340
Query: 1046 CHNNIMKQTMVDSSCRIL--TSDVFQDCNKLVDPEPYLDVCIYDTCSCESIGDCACFCDT 1103
C +++ C L T F+ C V + D C+ D C + + C
Sbjct: 1341 CDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQGLQH--LLCTH 1398
Query: 1104 IAAYAHVCAQHGKVV-TWRTATLCPQSCEERNLRENGYECEWRYNSCAPACQVTCQHP-E 1161
++ C G V WR CP +C + +Y+ CA C TC
Sbjct: 1399 MSTMTTTCQDAGHAVKPWREPHFCPMACPPNS----------KYSLCAKPCPDTCHSGFS 1448
Query: 1162 PLACPVQCVEGCHAHCPPGKILDELLQTCVDPEDCPVCEVAGRRFASGKK 1211
+ C +CVE C C PG +L L C+ C AG F G++
Sbjct: 1449 GMFCSDRCVEAC--ECNPGFVLSGL--ECIPRSQCGCLHPAGSYFKVGER 1494
Score = 150 bits (378), Expect = 2e-35
Identities = 130/515 (25%), Positives = 209/515 (40%), Gaps = 79/515 (15%)
Query: 769 PPMVKLVCPADNLRAEGLE-CTKTCQN-YDLECMSMGCVSGCLCPPGMVRHENRCVALER 826
P + CP ++ + + C TC + + S CV C C PG V C+ +
Sbjct: 1419 PHFCPMACPPNSKYSLCAKPCPDTCHSGFSGMFCSDRCVEACECNPGFVLSGLECIPRSQ 1478
Query: 827 CPCFHQ-GKEYAPGET-VKIGCNT-CVC------RDRKWNC-TDHVCD------------ 864
C C H G + GE K GC CVC R + W C C
Sbjct: 1479 CGCLHPAGSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQG 1538
Query: 865 -ATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPGTFRILVGNKGCSHPSVKCKK 923
ATC+ G HYLTFDG + F G C YVL + + ++ ++ S +
Sbjct: 1539 AATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVV---------SATNEN 1589
Query: 924 RVTIL----VEGGEIELFDGEVNVKRPMK--------------DETHFEVVESGRYIILL 965
R IL ++ + +FD +++ R K + + S ++L
Sbjct: 1590 RGGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLY 1649
Query: 966 LGKALSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSW 1025
L V +D + V + +Y ++CGLCGN++ +D + ++ D + G +W
Sbjct: 1650 TNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAW 1709
Query: 1026 KVSSQCADTRKVPLDSSPATCHNNIMKQTMVDSSCRILTSDV--FQDCNKLVDPEPYLDV 1083
K+ + ++ + P++C N M + +C IL + F C+++V P+
Sbjct: 1710 KLP-ESSEPGCFLVGGKPSSCQENSMADAW-NKNCAILINPQGPFSQCHQVVPPQSSFAS 1767
Query: 1084 CIYDTCSCESIGDCACFCDTIAAYAHVCAQHGKVVTWRTATLCPQSCEERNLRENGYECE 1143
C++ C + GD C ++ AYA +CAQ G+ WR T CP C +
Sbjct: 1768 CVHGQCGTK--GDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRCPPGS--------- 1816
Query: 1144 WRYNSCAPACQVTCQH-PEPLACP--VQCVEGCHAHCPPGKILDELLQTCVDPEDCPVCE 1200
Y+ C+ C TC P CP + C E C C G IL +CV C +
Sbjct: 1817 -SYSPCSSPCPDTCSSINNPRDCPKALPCAESC--ECQKGHILSG--TSCVPLGQCGCTD 1871
Query: 1201 VAGRRFASGKKVTLNPSDPEHCQICHCDV-VNLTC 1234
AG G++ ++ ++C C V N+TC
Sbjct: 1872 PAGSYHPVGERWY---TENTCTRLCTCSVHNNITC 1903
Score = 132 bits (332), Expect = 5e-30
Identities = 117/455 (25%), Positives = 183/455 (40%), Gaps = 63/455 (13%)
Query: 763 RSLSCRPPMVK------LVCPADNLRAEGL-ECTKTCQNYDLEC----MSMGCVSGCLCP 811
+S +PP+ + L CPA + L C+ +C + D C + C GC+C
Sbjct: 2192 QSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEGCICQ 2251
Query: 812 PGMVRHENRCVALERCPC--FHQGKEYAPGETVKIGCNT-CVCRDRKWNCTDHVCDA--- 865
PG V E++CV +C C H G V GC CVC C D C +
Sbjct: 2252 PGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGAIQCGDFRCPSGSH 2311
Query: 866 ------------------TCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPGTFRI 907
CS G YLTFDG Y G YVL++ G +
Sbjct: 2312 CQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPL 2371
Query: 908 LVGNKGCSHP--SVKCKKRVTILVEGGEIELFDG---EVNVKR---PMKDETHFEVVESG 959
LV + P S + V V G +++L G VN ++ P + H V G
Sbjct: 2372 LVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWG 2431
Query: 960 RYIILLLGKALSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPV 1019
+ + L+ L V + + + L Y+ V GLCGN+D + ND+ + + ++
Sbjct: 2432 QRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLN 2491
Query: 1020 DFGNSWKVSSQCA---DTRKVPLDSSPATCHNNIMKQTMVD------------SSCRILT 1064
FGNSW+V ++ A R +P + + V +CR+L
Sbjct: 2492 TFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLA 2551
Query: 1065 --SDVFQDCNKLVDPEPYLDVCIYDTCSCESIGDC-ACFCDTIAAYAHVCAQHGKVVT-W 1120
F C++ V PEP+ + C+ D CS + + C ++ YA +C + G + W
Sbjct: 2552 DPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGW 2611
Query: 1121 RTATLCPQSCEERNLRENGYECEWRYNSCAPACQV 1155
R TLC C + + +G +C + + C+V
Sbjct: 2612 RDRTLCESPCLQNPCQNDG-QCREQGATFTCECEV 2645
Score = 127 bits (320), Expect = 1e-28
Identities = 105/445 (23%), Positives = 176/445 (39%), Gaps = 44/445 (9%)
Query: 1879 CMDEDGNEKRPGDVWTLPDQCHTVTCQPDGQTLLKSHRVNCDRGLRPSCPNSQSPVKVEE 1938
C+ G+ + G+ W P C+ ++R+ C C + + +
Sbjct: 1481 CLHPAGSYFKVGERWYKPGCKELCVCE-------SNNRIRCQPW---RCRAQEFCGQQDG 1530
Query: 1939 TCGCRWTCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQ---NKEQDLEVILHNGACSP 1995
GC CT S H +TFDG G+C+YVL + ++ QD ++ +
Sbjct: 1531 IYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENR 1590
Query: 1996 GA--RQGCMKSIEVKHSALSVELHSDMEVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFN 2053
G +K++ V LS+ L +V +NG V++P V + + + +
Sbjct: 1591 GGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYT 1650
Query: 2054 HLGHIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQE 2113
+ G + + P ++ + GLCG + N +D + D + D L
Sbjct: 1651 NFGLQVRY--DGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAA 1708
Query: 2114 WTV---QRPG--------QTCQPILEEQCLVPDSSHCQVLLLPL--FAECHKVLAPATFY 2160
W + PG +CQ E + +C +L+ P F++CH+V+ P + +
Sbjct: 1709 WKLPESSEPGCFLVGGKPSSCQ---ENSMADAWNKNCAILINPQGPFSQCHQVVPPQSSF 1765
Query: 2161 AICQQDSCHQE----QVCEVIASYAHLCRTNGVCVDWRTPDFCAMSCPPSLVYNHCEHGC 2216
A C C + +C + +YA LC G WR FC M CPP Y+ C C
Sbjct: 1766 ASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRCPPGSSYSPCSSPC 1825
Query: 2217 PRHCDGNVSSCGDHP-----SEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAW 2271
P C ++++ D P +E C C ++ SCVP C C G H E W
Sbjct: 1826 PDTC-SSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQC-GCTDPAGSYHPVGERW 1883
Query: 2272 VPDHQPCQICTCLSGRKVNCTTQPC 2296
++ ++CTC + C C
Sbjct: 1884 YTENTCTRLCTCSVHNNITCFQSTC 1908
Score = 115 bits (288), Expect = 6e-25
Identities = 116/446 (26%), Positives = 161/446 (36%), Gaps = 68/446 (15%)
Query: 1889 PGDVWTLPDQCHTVTCQPDGQTLLKSHRVNCDR---GLRPSCPNSQSPVKVEETCGCRWT 1945
PG W P+ C P RV C G C G T
Sbjct: 1104 PGAEWFSPNCTEHCRCWPGS-------RVECQISQCGTHTVCQLKNGQYGCHPYAG---T 1153
Query: 1946 CPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKEQDLEVILHNGACSPGARQ---GCM 2002
C+ G H VTFDG++F G C+Y+L Q + A + Q C+
Sbjct: 1154 ATCLVYGDP--HYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEGVSCL 1211
Query: 2003 KSIEVKHSALSVELHSDMEVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHLGHIFTFT 2062
+ V +V L V G+ V++P + V+ LG F
Sbjct: 1212 SKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSK---GVF-----------LGASGRFV 1257
Query: 2063 PQNNEFQLQLS-----------PKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLV 2111
EF L++ T++ K GLCG D N ND + DG+ D + L
Sbjct: 1258 ELQTEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELG 1317
Query: 2112 QEW-TVQRPGQTCQPILEEQCLVPDSSHCQVLLLPLFA-----------ECHKVLAPATF 2159
W T Q Q CQ DSS + P F C + A+F
Sbjct: 1318 NSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASF 1377
Query: 2160 YAICQQDSCH----QEQVCEVIASYAHLCRTNGVCVD-WRTPDFCAMSCPPSLVYNHCEH 2214
+ C D C Q +C +++ C+ G V WR P FC M+CPP+ Y+ C
Sbjct: 1378 FDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAK 1437
Query: 2215 GCPRHCDGNVSS--CGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWV 2272
CP C S C D E C C P V+ C+P C C+ G + E W
Sbjct: 1438 PCPDTCHSGFSGMFCSDRCVEACECNPGFVLSGLECIPRSQC-GCLHPAGSYFKVGERW- 1495
Query: 2273 PDHQP-C-QICTCLSGRKVNCTTQPC 2296
++P C ++C C S ++ C C
Sbjct: 1496 --YKPGCKELCVCESNNRIRCQPWRC 1519
Score = 110 bits (276), Expect = 1e-23
Identities = 112/487 (22%), Positives = 172/487 (35%), Gaps = 94/487 (19%)
Query: 788 CTKTCQ--NYDLEC-MSMGCVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAP-GE--- 840
C TC N +C ++ C C C G + CV L +C C Y P GE
Sbjct: 1825 CPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWY 1884
Query: 841 TVKIGCNTCVCR-DRKWNCTDHVCD-------------------ATCSTIGMAHYLTFDG 880
T C C C C C G +HY++FDG
Sbjct: 1885 TENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDG 1944
Query: 881 LKYLFPGECQYVLVQDYCGSNPGTFRILVGNKGCSHPSVKCKKRVTILVEGGE------- 933
+ P C VLV+ V + + P K + G E
Sbjct: 1945 SNHSIPDACTLVLVK-------------VCHPAMALPFFKISAKHEKEEGGTEAFRLHEV 1991
Query: 934 -IELFDGEVNVKR--------------PMKDETHFEVVESGRYIILLLGKALSVVWDRHL 978
I+++D +V +++ + V S Y I+ + + V +D +
Sbjct: 1992 YIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNH 2051
Query: 979 SISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWK-------VSSQC 1031
+ + + TY KVCG+CGNF+ + ++L + +V +F NSWK S
Sbjct: 2052 LLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLL 2111
Query: 1032 ADTRKVPL---DSSPATCHNNIMKQTMVDSSCRILTSDVFQDCNKLVDPEPYLDVCIYDT 1088
D +++P ++ C +++ + L + V+ C +D P+L C
Sbjct: 2112 VDEQQIPAEQQENPSGNCRAADLRRAR-EKCEAALRAPVWAQCASRIDLTPFLVDCA--N 2168
Query: 1089 CSCESIGDCACFCDTIAAYAHVCAQHG-KVVTWRTATLCPQSCEERNLRENGYECEWRYN 1147
CE G C + A+ C G K WR ++ CP C + Y
Sbjct: 2169 TLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYS----------SYT 2218
Query: 1148 SCAPACQVTC----QHPEPLACPVQCVEGCHAHCPPGKILDELLQTCVDPEDCPVCEVAG 1203
+C P+C +C E P C EGC C PG +L E CV C + G
Sbjct: 2219 NCLPSCSPSCWDLDGRCEGAKVPSACAEGC--ICQPGYVLSE--DKCVPRSQCGCKDAHG 2274
Query: 1204 RRFASGK 1210
GK
Sbjct: 2275 GSIPLGK 2281
Score = 103 bits (258), Expect = 2e-21
Identities = 98/458 (21%), Positives = 177/458 (38%), Gaps = 56/458 (12%)
Query: 1879 CMDEDGNEKRPGDVWTLPDQCHTVTCQPDGQTLLKSHRVNCDRGLRPSCPNSQSPVKVEE 1938
C D G+ G+ W + C T C T + + C + +C +Q ++
Sbjct: 1869 CTDPAGSYHPVGERWYTENTC-TRLC-----TCSVHNNITC---FQSTCKPNQICWALDG 1919
Query: 1939 TCGCRWTCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKEQDLEVILHNGACSPGAR 1998
CR + VC H V+FDG N + +C+ VL + + + +
Sbjct: 1920 LLRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKE 1979
Query: 1999 QGCMKSIEVKHSALS-----VELHSDMEVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFN 2053
+G ++ + + V L V +N + V++P + V+V + ++ +
Sbjct: 1980 EGGTEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNI 2039
Query: 2054 HLGHIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQE 2113
+G F N+ ++++ P T+ K G+CG ++ ++ M+ V V
Sbjct: 2040 KIGVQVKFDG-NHLLEIEI-PTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNS 2097
Query: 2114 WTVQRPGQTCQPILEEQCLVP------DSSHCQ-------------VLLLPLFAECHKVL 2154
W + +CQ +L ++ +P S +C+ L P++A+C +
Sbjct: 2098 WKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRI 2157
Query: 2155 APATFYAICQQDSCH----QEQVCEVIASYAHLCRTNGVCVD-WRTPDFCAMSCPPSLVY 2209
F C C + +C+ + ++ C++ G+ WR FC + CP Y
Sbjct: 2158 DLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSY 2217
Query: 2210 NHCEHGCPRHC---DGNV------SSCGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGE 2260
+C C C DG S+C +EGC C P V+ E CVP C C
Sbjct: 2218 TNCLPSCSPSCWDLDGRCEGAKVPSAC----AEGCICQPGYVLSEDKCVPRSQC-GCKDA 2272
Query: 2261 DGVQHQFLEAWVPDHQPCQICTCLSGRKVNCTTQPCPT 2298
G ++WV + C C +G + C CP+
Sbjct: 2273 HGGSIPLGKSWV-SSGCTEKCVC-TGGAIQCGDFRCPS 2308
Score = 85.1 bits (209), Expect = 9e-16
Identities = 85/336 (25%), Positives = 134/336 (39%), Gaps = 48/336 (14%)
Query: 1950 CTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKE---QDLEVILHNGA--CSPGARQGCMKS 2004
C+ +TFDG +++L G +YVL + + + +E +L G P ++
Sbjct: 2331 CSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQE 2390
Query: 2005 IEVKHSALSVELHSDMEVTVNGRLVSVPY-VGGNMEVNVYGAIMHEVRFNHLGHIFTFTP 2063
+ V+L + +E+ VN + ++VPY ++ V ++G ++ V L + +F
Sbjct: 2391 VITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFEL--VVSFGG 2448
Query: 2064 QNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTVQ------ 2117
+ N + L P + GLCG D+N ND ML G +T + T W V+
Sbjct: 2449 RKNAV-ISL-PSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALL 2506
Query: 2118 -------------------RPGQTCQPILEEQCLVPDSSHCQVLLLPL--FAECHKVLAP 2156
R G EQ + C+VL P FA CH+ +AP
Sbjct: 2507 RFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAP 2566
Query: 2157 ATFYAICQQDSC-------HQEQVCEVIASYAHLCRTNGVCV-DWRTPDFCAMSCPPSLV 2208
F C D C +E C+V++ YA LC+ G + WR C C +
Sbjct: 2567 EPFQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCESPCLQNPC 2626
Query: 2209 YN--HC-EHGCPRHCDGNVSSCGDHPSEGCFCPPDK 2241
N C E G C+ V G E PP +
Sbjct: 2627 QNDGQCREQGATFTCECEVGYGGGLCMEPRDAPPPR 2662
Score = 50.4 bits (119), Expect = 2e-05
Identities = 28/96 (29%), Positives = 38/96 (39%), Gaps = 5/96 (5%)
Query: 2203 CPPSLVYNHCEHGCPRHCDGNVSSCGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDG 2262
CPP+ Y C CP C SCG EGC C P + + C+ +C C +
Sbjct: 1044 CPPNARYESC--ACPASCKSPRPSCGPLCREGCVCNPGFLFSDNHCIQASSC-NCFYNND 1100
Query: 2263 VQHQFLEAWVPDHQPCQICTCLSGRKVNCTTQPCPT 2298
E + P+ + C C G +V C C T
Sbjct: 1101 YYEPGAEWFSPN--CTEHCRCWPGSRVECQISQCGT 1134
Score = 49.7 bits (117), Expect = 4e-05
Identities = 27/85 (31%), Positives = 39/85 (45%), Gaps = 8/85 (9%)
Query: 652 CPKGQVYLQCGTPCNLTCRSLSYPDEECNEACLEGCFCPPGLYMDERGDCVPKAQCPCYY 711
CP Y C P + C+S P C C EGC C PG + C+ + C C+Y
Sbjct: 1044 CPPNARYESCACPAS--CKS---PRPSCGPLCREGCVCNPGFLFSDN-HCIQASSCNCFY 1097
Query: 712 DGEIFQP-EDIFSDHHT-MCYCEDG 734
+ + ++P + FS + T C C G
Sbjct: 1098 NNDYYEPGAEWFSPNCTEHCRCWPG 1122
>gi|134268640 tectorin alpha precursor [Homo sapiens]
Length = 2155
Score = 270 bits (690), Expect = 1e-71
Identities = 213/771 (27%), Positives = 314/771 (40%), Gaps = 81/771 (10%)
Query: 32 TARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRS----FSIIG--DFQNGKRVS-- 83
T+ C +FG +TFDG ++ F G C+YLLA C + S FS+ + + G VS
Sbjct: 319 TSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSVEAKNEHRRGSAVSWV 378
Query: 84 --LSVYLGEF-FDIHLFVNGTVTQGDQRVSMPYA-SKGLYLETEAGYYKLSGEAYGFVAR 139
LSV + + I G V D S+P G ++G +G +
Sbjct: 379 KELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGTVKIYQSGISTAVETDFGLLVT 438
Query: 140 IDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGEQW 199
DG + + Y N TCGLCGN+N DDF+ +G D SW + +
Sbjct: 439 FDGQHYASISVPGSYINSTCGLCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRVYHADWK 498
Query: 200 CERASPPS-SSCNISSGEMQKGLWEQCQLLKSTS-VFARCHPLVDPEPFVALCEKTLCEC 257
C+ + + C+ ++ + G + C L T C +VDP FV C LC
Sbjct: 499 CDSGCVDNCTQCDAATEALYFGS-DYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDLCSV 557
Query: 258 AGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPV--CPAGMEYRQCVSPCARTCQSL 315
C A+ YA C G+ + W + C CP+ Y C S C TC L
Sbjct: 558 RDNGTLLCQAIQAYALVCQALGIPIGDWRTQTGCVSTVQCPSFSHYSVCTSSCPDTCSDL 617
Query: 316 HINEMCQERCVDGCSCPEGQLLDEGLCVESTECPCVHSGKRYPPGTSLSRDCN---TCIC 372
+ C C +GC C +G +L CV +C C G Y G N C+C
Sbjct: 618 TASRNCATPCTEGCECNQGFVLSTSQCVPLHKCGCDFDGHYYTMGEFFWATANCTVQCLC 677
Query: 373 RNSQWI-CSNEEC-PGE------------------CLVTGQSHFKSFDNRYFTFSGICQY 412
+ C N+ C GE CL++ +FD + F Y
Sbjct: 678 EEGGDVYCFNKTCGSGEVCAVEDGYQGCFPKRETVCLLSQNQVLHTFDGASYAFPSEFSY 737
Query: 413 LLARDCQDHSFSIVIETVQCADDRDAVCTRSV-------TVRLPGLHNSLVKLKHGAGVA 465
L + C + + I+ + D R + V++ G+ S VKL
Sbjct: 738 TLLKTCPERPEYLEIDINKKKPDAGPAWLRGLRILVADQEVKIGGIGASEVKL------- 790
Query: 466 MDGQDVQLPLL--KGDLRIQHTVTASVRLSYGEDLQMDWDGRGRLLVKLSPVYAGKTCGL 523
+GQ+V+LP G L I ++ S G + + + G L ++LS Y T GL
Sbjct: 791 -NGQEVELPFFHPSGKLEIYRNKNSTTVESKGV-VTVQYSDIGLLYIRLSTTYFNCTGGL 848
Query: 524 CGNYNGNQGDDFLTPSGLAEPRVEDFGNAWK-----LHGDCQDLQKQHSDPCALNPRMTR 578
CG YN N D+F P+G + F +W +G+C DL K C + + +
Sbjct: 849 CGFYNANASDEFCLPNGKCTDNLAVFLESWTTFEEICNGECGDLLK----ACNNDSELLK 904
Query: 579 F--SEEACAVLTSP---TFEACHRAVSPLPYLRNCRYDVCSCSDGRECLCGALASYAAAC 633
F S C ++ P +F CH V+ Y R C + +C LC ++A YA+AC
Sbjct: 905 FYRSRSRCGIINDPSNSSFLECHGVVNVTAYYRTCLFRLCQSGGNESELCDSVARYASAC 964
Query: 634 AGRGVRVA-WREPGRCELNCPKGQVYLQCGTPCNLTCRSLSYPDEECNEACLEGCFCPPG 692
V V WR C L CP+ + +C T C TC +L+ C ++C EGC C G
Sbjct: 965 KNADVEVGPWRTYDFCPLECPENSHFEECIT-CTETCETLTL-GPICVDSCSEGCQCDEG 1022
Query: 693 LYMDERGDCVPKAQCPCYYDGEIFQPEDIF---SDHHTMCYCE--DGFMHC 738
Y CV +++C C ++G + F D CYC D +HC
Sbjct: 1023 -YALLGSQCVTRSECGCNFEGHQLATNETFWVDLDCQIFCYCSGTDNRVHC 1072
Score = 259 bits (661), Expect = 3e-68
Identities = 204/766 (26%), Positives = 314/766 (40%), Gaps = 96/766 (12%)
Query: 35 CSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRSFSIIGDFQNGKRVSLSVYLGEF--- 91
C L + ++TFDG+ Y+F SY L C +R + D K + +L
Sbjct: 713 CLLSQNQVLHTFDGASYAFPSEFSYTLLKTCPERPEYLEIDINKKKPDAGPAWLRGLRIL 772
Query: 92 -FDIHLFVNGT----VTQGDQRVSMPYASKGLYLETEAGYYKLSGEAYGFVA-RIDGSGN 145
D + + G V Q V +P+ LE + E+ G V + G
Sbjct: 773 VADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTVESKGVVTVQYSDIGL 832
Query: 146 FQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGEQWCERASP 205
+ LS YFN T GLCG +N A D+F G T + F SW
Sbjct: 833 LYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLESWTTFE---------- 882
Query: 206 PSSSCNISSGEMQKGLWEQCQLLK--------------STSVFARCHPLVDPEPFVALCE 251
CN G++ K +LLK S S F CH +V+ + C
Sbjct: 883 --EICNGECGDLLKACNNDSELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAYYRTCL 940
Query: 252 KTLCECAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCART 311
LC+ G C ++ YA C + + W + C CP + +C++ C T
Sbjct: 941 FRLCQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHFEECIT-CTET 999
Query: 312 CQSLHINEMCQERCVDGCSCPEGQLLDEGLCVESTECPCVHSGKR--------------- 356
C++L + +C + C +GC C EG L CV +EC C G +
Sbjct: 1000 CETLTLGPICVDSCSEGCQCDEGYALLGSQCVTRSECGCNFEGHQLATNETFWVDLDCQI 1059
Query: 357 --YPPGTSLSRDCNTCICRNSQWICSNE--------ECPGECLVTGQSHFKSFDNRYFTF 406
Y GT C T C++ ++ C E C+V+G H+ +FD F F
Sbjct: 1060 FCYCSGTDNRVHCETIPCKDDEY-CMEEGGLYYCQARTDASCIVSGYGHYLTFDGFPFDF 1118
Query: 407 SGICQYLL----ARDCQDHSFSIVIETVQCADDRD---AVCTRSVTVRLPGLHNSLVKLK 459
C +L +R D SF + T + +DRD A+ + V V + G ++ ++
Sbjct: 1119 QTSCPLILCTTGSRPSSD-SFPKFVVTAK-NEDRDPSLALWVKQVDVTVFG-YSIVIHRA 1175
Query: 460 HGAGVAMDGQDVQLPLLKGDLRIQ------HTVTASVRLSYGEDLQMDWDGRGRLLVKLS 513
+ V ++ + + LPL G +I H V V +G + DW + L + +
Sbjct: 1176 YKHTVLVNSERLYLPLKLGQGKINIFSFGFHVV---VETDFGLKVVYDW--KTFLSITVP 1230
Query: 514 PVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAW-KLHGDCQDLQKQHSDPCAL 572
T GLCG YNGN DD P GL V +FG +W K CQ D C
Sbjct: 1231 RSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSWVKRDTFCQ---VGCGDRCPS 1287
Query: 573 NPRMTRFS--EEACAVLTSPT--FEACHRAVSPLPYLRNCRYDVCSCSDGRECLCGALAS 628
++ FS ++ C+++ + F CH V+P + +NC +D C + C L +
Sbjct: 1288 CAKVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCIDGGAVQTACSWLQN 1347
Query: 629 YAAACAGRGVRVA-WREPGRCELNCPKGQVYLQCGTPCNLTCRSLSYPDEECNEACLEGC 687
YA+ C +G+ V WR C + CP Y C + C C ++ + C+ C+EGC
Sbjct: 1348 YASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQPRCAAIRLKSD-CSHYCVEGC 1406
Query: 688 FCPPGLYMDERGDCVPKAQCPCYYDGEIFQPEDIF--SDHHTMCYC 731
C G ++ + C+ C CY DG+ ++P+ +F SD C C
Sbjct: 1407 HCDAGYVLNGKS-CILPHSCGCYSDGKYYEPKQLFWNSDCTRRCRC 1451
Score = 221 bits (564), Expect = 6e-57
Identities = 187/719 (26%), Positives = 299/719 (41%), Gaps = 86/719 (11%)
Query: 33 ARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRSFSIIGDF-----QNGKRVSLSVY 87
A C + G TFDG + F C +L + S F + SL+++
Sbjct: 1098 ASCIVSGYGHYLTFDGFPFDFQTSCPLILCTTGSRPSSDSFPKFVVTAKNEDRDPSLALW 1157
Query: 88 LGEFFDIHLFVNGTVTQGDQRVSMPYASKGLYLETEAGYYKLSGEAYGFVARIDGSGNFQ 147
+ + D+ +F V + ++ S+ LYL + G K++ ++GF ++ +
Sbjct: 1158 VKQV-DVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLK 1216
Query: 148 VLLSDRYF----------NKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGE 197
V+ + F N T GLCG +N +DD G L S +F SW +
Sbjct: 1217 VVYDWKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSWV--KRD 1274
Query: 198 QWCE-RASPPSSSCNISSGEMQKGLWEQCQLLKS-TSVFARCHPLVDPEPFVALCEKTLC 255
+C+ SC G + + + C L+ + + F++CH V+P F C C
Sbjct: 1275 TFCQVGCGDRCPSCAKVEGFSK--VQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSC 1332
Query: 256 ECAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCARTCQSL 315
G ++ AC L YA TC +G+ + GW ++++C+ CP Y CVS C C ++
Sbjct: 1333 IDGGAVQTACSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQPRCAAI 1392
Query: 316 HINEMCQERCVDGCSCPEGQLLDEGLCVESTECPCVHSGKRYPP-----GTSLSRDCNTC 370
+ C CV+GC C G +L+ C+ C C GK Y P + +R C C
Sbjct: 1393 RLKSDCSHYCVEGCHCDAGYVLNGKSCILPHSCGCYSDGKYYEPKQLFWNSDCTRRCR-C 1451
Query: 371 ICRN-----SQWICSNEEC-------------PGECLVTGQSHFKSFDNRYFTFSGICQY 412
RN + S+EEC CL G F++FD + F C +
Sbjct: 1452 FRRNVIQCDPRQCKSDEECALRNGVRGCFSTKTSYCLAAGGGVFRTFDGAFLRFPANCAF 1511
Query: 413 LLARDCQ---DHSFSIVIETVQCADDRDAVCTRSVTVRLP---GLHNSLVKLKHGAGVAM 466
+L+ CQ D SF ++I + D ++T+ P ++ + + V +
Sbjct: 1512 VLSTICQKLPDISFQLII-------NFDKWSAPNLTIISPVYFYINEEQILINDRNTVKV 1564
Query: 467 DGQDVQLPLLKGDLRIQHTVTASVRLSYGEDLQMDWDGRGRLLVKLSPVYAGKTCGLCGN 526
+G V +P + G ++ + + D+Q+ ++G + + +S K CGLCGN
Sbjct: 1565 NGTQVNVPFITGLATKIYSSEGFLVIDTSPDIQIYYNGFNVIKISISERLQNKVCGLCGN 1624
Query: 527 YNGNQGDDFLTPSGLAEPRVEDFGNAWKLHG--------DCQDLQ-KQHSDPCALNPRMT 577
+NG+ DD++T G +WK +G C +LQ Q++ C
Sbjct: 1625 FNGDLTDDYVTLRGKPVVSSVVLAQSWKTNGMQKRPLAPSCNELQFSQYAAMCDNVHIQK 1684
Query: 578 RFSEEACAVLTSPT--FEACHRAVSPLPYLRNCRYDVCSCSDGRECLCGALASYAAACAG 635
+ C LT F+ C+ + PLP+ +C D C S + LCG+LA+Y AC
Sbjct: 1685 MQGDGYCLKLTDMKGFFQPCYGLLDPLPFYESCYLDGC-YSHKKFQLCGSLAAYGEACRS 1743
Query: 636 RGV-RVAWREPGRCELNCPKGQVYLQC-GTPC-NLTCRSLSYPDEECNEACLEGCFCPP 691
G+ W E C G V C G C N TC E N L GC PP
Sbjct: 1744 FGILSTEWIEKENC-----SGVVEDPCVGADCPNRTC-------ELGNGRELCGCIEPP 1790
Score = 160 bits (404), Expect = 2e-38
Identities = 116/384 (30%), Positives = 172/384 (44%), Gaps = 27/384 (7%)
Query: 370 CICRNSQWICSNEECPGECLVTGQSHFKSFDNRYFTFSGICQYLLARDCQDHSFSIVIET 429
C + + CS E C+V G+ H+ +FD F F G C YLLAR C S S+ +
Sbjct: 305 CEPKGKFFYCSAVET-STCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTS-SLPFFS 362
Query: 430 VQCADDR---DAVC-TRSVTVRLPGLHNSLVKLKHGAGVAMDGQDVQLPLLK--GDLRI- 482
V+ ++ AV + ++V + G + K +G V ++ LP+ G ++I
Sbjct: 363 VEAKNEHRRGSAVSWVKELSVEVNGYKILIPKGSYGR-VKVNDLVTSLPVTLDLGTVKIY 421
Query: 483 QHTVTASVRLSYGEDLQMDWDGRGRLLVKLSPVYAGKTCGLCGNYNGNQGDDFLTPSGLA 542
Q ++ +V +G L + +DG+ + + Y TCGLCGNYN N DDFL P G
Sbjct: 422 QSGISTAVETDFG--LLVTFDGQHYASISVPGSYINSTCGLCGNYNKNPLDDFLRPDGRP 479
Query: 543 EPRVEDFGNAWKL-HGD--CQDLQKQHSDPCALNPRMTRFSEEACAVLT---SPTFEACH 596
V D G +W++ H D C + C F + C L P +E C
Sbjct: 480 AMSVLDLGESWRVYHADWKCDSGCVDNCTQCDAATEALYFGSDYCGFLNKTDGPLWE-CG 538
Query: 597 RAVSPLPYLRNCRYDVCSCSDGRECLCGALASYAAACAGRGVRVA-WREPGRC--ELNCP 653
V P ++ +C YD+CS D LC A+ +YA C G+ + WR C + CP
Sbjct: 539 TVVDPTAFVHSCVYDLCSVRDNGTLLCQAIQAYALVCQALGIPIGDWRTQTGCVSTVQCP 598
Query: 654 KGQVYLQCGTPCNLTCRSLSYPDEECNEACLEGCFCPPGLYMDERGDCVPKAQCPCYYDG 713
Y C + C TC L+ C C EGC C G + CVP +C C +DG
Sbjct: 599 SFSHYSVCTSSCPDTCSDLT-ASRNCATPCTEGCECNQGFVL-STSQCVPLHKCGCDFDG 656
Query: 714 EIFQPEDIF---SDHHTMCYCEDG 734
+ + F ++ C CE+G
Sbjct: 657 HYYTMGEFFWATANCTVQCLCEEG 680
Score = 137 bits (345), Expect = 1e-31
Identities = 127/509 (24%), Positives = 204/509 (40%), Gaps = 69/509 (13%)
Query: 774 LVCPADNLRAEGLECTKTCQNYDLECMSM-GCVSGCLCPPGMVRHENRCVALERCPCFHQ 832
L CP ++ E + CT+TC+ L + + C GC C G ++CV C C +
Sbjct: 982 LECPENSHFEECITCTETCETLTLGPICVDSCSEGCQCDEGYALLGSQCVTRSECGCNFE 1041
Query: 833 GKEYAPGETV-----------------KIGCNTCVCRDRKWNCTD---HVC----DATCS 868
G + A ET ++ C T C+D ++ + + C DA+C
Sbjct: 1042 GHQLATNETFWVDLDCQIFCYCSGTDNRVHCETIPCKDDEYCMEEGGLYYCQARTDASCI 1101
Query: 869 TIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPGT-----FRILVGNKGCSHPSVKCKK 923
G HYLTFDG + F C +L GS P + F + N+ K
Sbjct: 1102 VSGYGHYLTFDGFPFDFQTSCPLILCT--TGSRPSSDSFPKFVVTAKNEDRDPSLALWVK 1159
Query: 924 RVTILVEGGEIELFDGE-----VNVKR---PMK-DETHFEVVESGRYIILLLGKALSVVW 974
+V + V G I + VN +R P+K + + G ++++ L VV+
Sbjct: 1160 QVDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVY 1219
Query: 975 DRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSW-KVSSQCAD 1033
D +S+ + ++ Q GLCG ++G ++DL + +FG SW K + C
Sbjct: 1220 DWKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSWVKRDTFC-- 1277
Query: 1034 TRKVPLDSSPATCHNNIMKQTMVDSSCRILTSD--VFQDCNKLVDPEPYLDVCIYDTCSC 1091
+V +C + + V C ++ + F C+ V+P + C++D SC
Sbjct: 1278 --QVGCGDRCPSC-AKVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFD--SC 1332
Query: 1092 ESIGDCACFCDTIAAYAHVCAQHGKVVT-WRTATLCPQSCEERNLRENGYECEWRYNSCA 1150
G C + YA C G VT WR T C +C + Y SC
Sbjct: 1333 IDGGAVQTACSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNS----------HYESCV 1382
Query: 1151 PACQVTCQHPEPLA-CPVQCVEGCHAHCPPGKILDELLQTCVDPEDCPVCEVAGRRFASG 1209
CQ C + C CVEGC HC G +L+ ++C+ P C C G ++
Sbjct: 1383 SVCQPRCAAIRLKSDCSHYCVEGC--HCDAGYVLNG--KSCILPHSCG-CYSDG-KYYEP 1436
Query: 1210 KKVTLNPSDPEHCQICHCDVVNLTCEACQ 1238
K++ N C+ +V+ C+
Sbjct: 1437 KQLFWNSDCTRRCRCFRRNVIQCDPRQCK 1465
Score = 116 bits (291), Expect = 3e-25
Identities = 117/432 (27%), Positives = 165/432 (38%), Gaps = 50/432 (11%)
Query: 1930 SQSPVKVEETCGCRWTCPCV----CTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKEQDLE 1985
S SP +V E G + C V C H TFDG F GSC+Y+L + Q
Sbjct: 298 SCSPYEVCEPKGKFFYCSAVETSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSS 357
Query: 1986 VILHNGACSPGARQGCMKS------IEVKHSALSVELHSDMEVTVNGRLVSVPYVGGNME 2039
+ + R+G S +EV + + S V VN + S+P
Sbjct: 358 LPFFSVEAKNEHRRGSAVSWVKELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGT 417
Query: 2040 VNVYGAIMHEVRFNHLGHIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLR 2099
V +Y + + G + TF Q+ + P ++ + T GLCG ++N +DF+
Sbjct: 418 VKIYQSGISTAVETDFGLLVTFDGQH--YASISVPGSYINSTCGLCGNYNKNPLDDFLRP 475
Query: 2100 DGTVTTDWKTLVQEWTVQRPGQTCQPILEEQCLVPD---------SSHCQVLLL---PLF 2147
DG L + W V C + C D S +C L PL+
Sbjct: 476 DGRPAMSVLDLGESWRVYHADWKCDSGCVDNCTQCDAATEALYFGSDYCGFLNKTDGPLW 535
Query: 2148 AECHKVLAPATFYAICQQDSCHQEQ----VCEVIASYAHLCRTNGVCV-DWRTPDFC--A 2200
EC V+ P F C D C +C+ I +YA +C+ G+ + DWRT C
Sbjct: 536 -ECGTVVDPTAFVHSCVYDLCSVRDNGTLLCQAIQAYALVCQALGIPIGDWRTQTGCVST 594
Query: 2201 MSCPPSLVYNHCEHGCPRHCDGNVSS--CGDHPSEGCFCPPDKVMLEGSCVPEEACTQCI 2258
+ CP Y+ C CP C +S C +EGC C V+ CVP C
Sbjct: 595 VQCPSFSHYSVCTSSCPDTCSDLTASRNCATPCTEGCECNQGFVLSTSQCVPLHKC---- 650
Query: 2259 GEDGVQHQFLEA---WVPDHQPCQICTCLSGRKVNCTTQPCPTAKAPTCGLCEVARLRQN 2315
G D H + W + Q C C G V C + TCG EV +
Sbjct: 651 GCDFDGHYYTMGEFFWATANCTVQ-CLCEEGGDVYCFNK--------TCGSGEVCAVEDG 701
Query: 2316 ADQCCPEYECVC 2327
C P+ E VC
Sbjct: 702 YQGCFPKRETVC 713
Score = 100 bits (250), Expect = 2e-20
Identities = 127/513 (24%), Positives = 195/513 (38%), Gaps = 90/513 (17%)
Query: 788 CTKTCQNYDLEC-MSMGCVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAPGETVKIGC 846
C TC + + C GC C G V ++CV L +C C G Y GE
Sbjct: 610 CPDTCSDLTASRNCATPCTEGCECNQGFVLSTSQCVPLHKCGCDFDGHYYTMGEFFWATA 669
Query: 847 NT---CVCRD-------RKWNCTDHVC-------------DATCSTIGMAHYLTFDGLKY 883
N C+C + K + VC + C TFDG Y
Sbjct: 670 NCTVQCLCEEGGDVYCFNKTCGSGEVCAVEDGYQGCFPKRETVCLLSQNQVLHTFDGASY 729
Query: 884 LFPGECQYVLVQDYCGSNPGTFRILVGNKGCSHPSVKCKKRVTILVEGGEIELFDGEVNV 943
FP E Y L++ C P I + NK + + ILV E+++ G +
Sbjct: 730 AFPSEFSYTLLKT-CPERPEYLEIDI-NKKKPDAGPAWLRGLRILVADQEVKI--GGIGA 785
Query: 944 KRPMKDETHFEVV---ESGRYIIL-----LLGKALSVVWDRHLSISVV---LKQTYQEKV 992
+ E+ SG+ I ++ VV ++ I ++ L TY
Sbjct: 786 SEVKLNGQEVELPFFHPSGKLEIYRNKNSTTVESKGVVTVQYSDIGLLYIRLSTTYFNCT 845
Query: 993 CGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKV-----SSQCADTRKVPLDSSPATCH 1047
GLCG ++ +++ N + ++ F SW + +C D K C+
Sbjct: 846 GGLCGFYNANASDEFCLPNGKCTDNLAVFLESWTTFEEICNGECGDLLKA--------CN 897
Query: 1048 NN--IMKQTMVDSSCRIL---TSDVFQDCNKLVDPEPYLDVCIYDTCSCESIGDCACFCD 1102
N+ ++K S C I+ ++ F +C+ +V+ Y C++ C +S G+ + CD
Sbjct: 898 NDSELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAYYRTCLFRLC--QSGGNESELCD 955
Query: 1103 TIAAYAHVCAQHG-KVVTWRTATLCPQSCEERNLRENGYECEWRYNSCAPACQVTCQHPE 1161
++A YA C +V WRT CP C E + E EC +C C+ P
Sbjct: 956 SVARYASACKNADVEVGPWRTYDFCPLECPENSHFE---EC----ITCTETCETLTLGP- 1007
Query: 1162 PLACPVQCVEGCHAHCPPGKILDELLQTCVDPEDCPVCEVAGRRFASGKKVTLNPSDPEH 1221
C C EGC C G L L CV +C C G + A+ + ++
Sbjct: 1008 --ICVDSCSEGC--QCDEGYAL--LGSQCVTRSECG-CNFEGHQLATNETFWVDLD---- 1056
Query: 1222 CQI-CHCDVVN-------LTC---EACQEPGGL 1243
CQI C+C + + C E C E GGL
Sbjct: 1057 CQIFCYCSGTDNRVHCETIPCKDDEYCMEEGGL 1089
Score = 100 bits (249), Expect = 2e-20
Identities = 95/404 (23%), Positives = 149/404 (36%), Gaps = 60/404 (14%)
Query: 752 VLSSPLSHRSKRSLSCRPPMVKLVCPADNLRAEGLECTKTCQNYDLECMSMGCVSGCLCP 811
V P SH C+P C A L+++ C +Y CV GC C
Sbjct: 1370 VTCPPNSHYESCVSVCQPR-----CAAIRLKSD-------CSHY--------CVEGCHCD 1409
Query: 812 PGMVRHENRCVALERCPCFHQGKEYAPGE-------TVKIGC---NTCVCRDRKWNCTDH 861
G V + C+ C C+ GK Y P + T + C N C R+ +
Sbjct: 1410 AGYVLNGKSCILPHSCGCYSDGKYYEPKQLFWNSDCTRRCRCFRRNVIQCDPRQCKSDEE 1469
Query: 862 V--------CDAT----CSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPG-TFRIL 908
C +T C G + TFDG FP C +VL C P +F+++
Sbjct: 1470 CALRNGVRGCFSTKTSYCLAAGGGVFRTFDGAFLRFPANCAFVL-STICQKLPDISFQLI 1528
Query: 909 VGNKGCSHPSVKCKKRVTILVEGGEIELFDGEV------NVKRPMKDETHFEVVESGRYI 962
+ S P++ V + +I + D V P ++ S ++
Sbjct: 1529 INFDKWSAPNLTIISPVYFYINEEQILINDRNTVKVNGTQVNVPFITGLATKIYSSEGFL 1588
Query: 963 ILLLGKALSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFG 1022
++ + + ++ I + + + Q KVCGLCGNF+G +D + + V
Sbjct: 1589 VIDTSPDIQIYYNGFNVIKISISERLQNKVCGLCGNFNGDLTDDYVTLRGKPVVSSVVLA 1648
Query: 1023 NSWKVSSQ-----CADTRKVPLDSSPATCHNNIMKQTMVDSSCRILT--SDVFQDCNKLV 1075
SWK + ++ A C N +++ D C LT FQ C L+
Sbjct: 1649 QSWKTNGMQKRPLAPSCNELQFSQYAAMCDNVHIQKMQGDGYCLKLTDMKGFFQPCYGLL 1708
Query: 1076 DPEPYLDVCIYDTCSCESIGDCACFCDTIAAYAHVCAQHGKVVT 1119
DP P+ + C D C C ++AAY C G + T
Sbjct: 1709 DPLPFYESCYLDGCYSHKKFQ---LCGSLAAYGEACRSFGILST 1749
Score = 100 bits (248), Expect = 3e-20
Identities = 98/391 (25%), Positives = 158/391 (40%), Gaps = 52/391 (13%)
Query: 1941 GCRWTCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQN---KEQDLEVILHNGACSPGA 1997
GC VC S + + TFDG ++ SY L + + + LE+ ++ P A
Sbjct: 704 GCFPKRETVCLLSQNQVLHTFDGASYAFPSEFSYTLLKTCPERPEYLEIDINKK--KPDA 761
Query: 1998 RQGCMKSIEVKHSALSVELHS--DMEVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHL 2055
++ + + + V++ EV +NG+ V +P+ + ++ +Y +
Sbjct: 762 GPAWLRGLRILVADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRN-KNSTTVESK 820
Query: 2056 GHIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWT 2115
G + ++LS T+ + T GLCG + N +++F L +G T + ++ WT
Sbjct: 821 GVVTVQYSDIGLLYIRLST-TYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLESWT 879
Query: 2116 VQRPGQTCQPILEEQC---------------LVPDSSHCQVLLLP---LFAECHKVLAPA 2157
T + I +C S C ++ P F ECH V+
Sbjct: 880 ------TFEEICNGECGDLLKACNNDSELLKFYRSRSRCGIINDPSNSSFLECHGVVNVT 933
Query: 2158 TFYAICQ----QDSCHQEQVCEVIASYAHLCRTNGVCV-DWRTPDFCAMSCPPSLVYNHC 2212
+Y C Q ++ ++C+ +A YA C+ V V WRT DFC + CP + + C
Sbjct: 934 AYYRTCLFRLCQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHFEEC 993
Query: 2213 EHGCPRHCDGNVSS--CGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFL-- 2268
C C+ C D SEGC C +L CV C G + HQ
Sbjct: 994 -ITCTETCETLTLGPICVDSCSEGCQCDEGYALLGSQCVTRSEC----GCNFEGHQLATN 1048
Query: 2269 -EAWVPDHQPCQICTCLSG--RKVNCTTQPC 2296
WV CQI SG +V+C T PC
Sbjct: 1049 ETFWV--DLDCQIFCYCSGTDNRVHCETIPC 1077
Score = 100 bits (248), Expect = 3e-20
Identities = 95/383 (24%), Positives = 145/383 (37%), Gaps = 36/383 (9%)
Query: 1940 CGCRWTCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKEQDLE-------VILHNGA 1992
C R C+ +G H +TFDG F SC +L + V N
Sbjct: 1092 CQARTDASCIVSGYG--HYLTFDGFPFDFQTSCPLILCTTGSRPSSDSFPKFVVTAKNED 1149
Query: 1993 CSPGARQGCMKSIEVKHSALSVELHSDME--VTVNGRLVSVPYVGGNMEVNVYGAIMHEV 2050
P +K ++V S+ +H + V VN + +P G ++N++ H V
Sbjct: 1150 RDPSLALW-VKQVDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVV 1208
Query: 2051 RFNHLGHIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTL 2110
G + + F P++ + TYGLCG + N +D + G + +
Sbjct: 1209 VETDFGLKVVYDWKT--FLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEF 1266
Query: 2111 VQEWTVQRPGQTCQPILEEQC----LVPDSSHCQVL--LLP----LFAECHKVLAPATFY 2160
Q W + CQ ++C V S Q L L+P F++CH + P FY
Sbjct: 1267 GQSWV--KRDTFCQVGCGDRCPSCAKVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFY 1324
Query: 2161 AICQQDSCHQ----EQVCEVIASYAHLCRTNGVCVD-WRTPDFCAMSCPPSLVYNHCEHG 2215
C DSC + C + +YA C+T G+ V WR C ++CPP+ Y C
Sbjct: 1325 KNCLFDSCIDGGAVQTACSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSV 1384
Query: 2216 CPRHCDG--NVSSCGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWVP 2273
C C S C + EGC C V+ SC+ +C C + W
Sbjct: 1385 CQPRCAAIRLKSDCSHYCVEGCHCDAGYVLNGKSCILPHSC-GCYSDGKYYEPKQLFWNS 1443
Query: 2274 DHQPCQICTCLSGRKVNCTTQPC 2296
D + C C + C + C
Sbjct: 1444 D--CTRRCRCFRRNVIQCDPRQC 1464
Score = 99.0 bits (245), Expect = 6e-20
Identities = 101/406 (24%), Positives = 152/406 (37%), Gaps = 45/406 (11%)
Query: 826 RCPCFHQGKEYAPGETVKIGCNTCVCRDRKWNCTDHVCDATCSTIGMAHYLTFDGLKYLF 885
+C C E E C + + + C+ V +TC G HY TFDG + F
Sbjct: 282 KCRCLDFNNEIYCQEASCSPYEVCEPKGKFFYCSA-VETSTCVVFGEPHYHTFDGFLFHF 340
Query: 886 PGECQYVLV-QDYCGSNPGTFRILVGNKGCSHPSVKCKKRVTILVEGGEIELFDG----- 939
G C Y+L Q S+ F + N+ +V K +++ V G +I + G
Sbjct: 341 QGSCAYLLARQCLQTSSLPFFSVEAKNEHRRGSAVSWVKELSVEVNGYKILIPKGSYGRV 400
Query: 940 ---EVNVKRPMK-DETHFEVVESGRYIILLLGKALSVVWDRHLSISVVLKQTYQEKVCGL 995
++ P+ D ++ +SG + L V +D S+ + +Y CGL
Sbjct: 401 KVNDLVTSLPVTLDLGTVKIYQSGISTAVETDFGLLVTFDGQHYASISVPGSYINSTCGL 460
Query: 996 CGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKV-------SSQCADTRKVPLDSSPATCHN 1048
CGN++ +D + + +D G SW+V S C D + C
Sbjct: 461 CGNYNKNPLDDFLRPDGRPAMSVLDLGESWRVYHADWKCDSGCVD--------NCTQCDA 512
Query: 1049 NIMKQTMVDSSCRIL--TSDVFQDCNKLVDPEPYLDVCIYDTCSCESIGDCACFCDTIAA 1106
C L T +C +VDP ++ C+YD CS G C I A
Sbjct: 513 ATEALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDLCSVRDNG--TLLCQAIQA 570
Query: 1107 YAHVCAQHG-KVVTWRTATLCPQSCEERNLRENGYECEWRYNSCAPACQVTCQH-PEPLA 1164
YA VC G + WRT T C + + + Y+ C +C TC
Sbjct: 571 YALVCQALGIPIGDWRTQTGCVSTVQCPSFS--------HYSVCTSSCPDTCSDLTASRN 622
Query: 1165 CPVQCVEGCHAHCPPGKILDELLQTCVDPEDCPVCEVAGRRFASGK 1210
C C EGC C G +L CV C C+ G + G+
Sbjct: 623 CATPCTEGC--ECNQGFVLS--TSQCVPLHKCG-CDFDGHYYTMGE 663
Score = 88.2 bits (217), Expect = 1e-16
Identities = 86/332 (25%), Positives = 135/332 (40%), Gaps = 57/332 (17%)
Query: 25 GTRG--RSSTARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKR---SFSIIGDFQNG 79
G RG + T+ C G TFDG+ F C+++L+ CQK SF +I +F
Sbjct: 1475 GVRGCFSTKTSYCLAAGGGVFRTFDGAFLRFPANCAFVLSTICQKLPDISFQLIINFDKW 1534
Query: 80 KRVSLSVYLGEFFDIH---LFVN--GTVTQGDQRVSMP---------YASKG-LYLETEA 124
+L++ +F I+ + +N TV +V++P Y+S+G L ++T
Sbjct: 1535 SAPNLTIISPVYFYINEEQILINDRNTVKVNGTQVNVPFITGLATKIYSSEGFLVIDTSP 1594
Query: 125 G---YYKLSGEAYGFVARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLT 181
YY +G ++ +S+R NK CGLCGNFN DD++T G
Sbjct: 1595 DIQIYY-------------NGFNVIKISISERLQNKVCGLCGNFNGDLTDDYVTLRGKPV 1641
Query: 182 SDPYDFANSWALSSGEQWCERASPPSSSCNISSGEMQKGLWEQCQL---------LKSTS 232
A SW + ++ P + SCN + + + LK T
Sbjct: 1642 VSSVVLAQSWKTNGMQK-----RPLAPSCNELQFSQYAAMCDNVHIQKMQGDGYCLKLTD 1696
Query: 233 V---FARCHPLVDPEPFVALCEKTLCECAGGLECACPALLEYARTCAQEGMVLYGWTDHS 289
+ F C+ L+DP PF C C + C +L Y C G++ W +
Sbjct: 1697 MKGFFQPCYGLLDPLPFYESCYLDGCYSHKKFQ-LCGSLAAYGEACRSFGILSTEWIEKE 1755
Query: 290 ACSPVCPAGMEYRQCVSPCARTCQSLHINEMC 321
CS V C + RTC+ + E+C
Sbjct: 1756 NCSGVVEDPCVGADCPN---RTCELGNGRELC 1784
Score = 54.3 bits (129), Expect = 2e-06
Identities = 69/318 (21%), Positives = 122/318 (38%), Gaps = 36/318 (11%)
Query: 1914 SHRVNCDRGLRPSCPNSQSPVKVEETC-------GCRWTCPCVCTGSSTRHIVTFDGQNF 1966
+ R C R C Q K +E C GC T C + TFDG
Sbjct: 1446 TRRCRCFRRNVIQCDPRQC--KSDEECALRNGVRGCFSTKTSYCLAAGGGVFRTFDGAFL 1503
Query: 1967 KLTGSCSYVLFQ--NKEQDLEV-ILHNGACSPGARQGCMKSIEVKHSALSVELHSDMEVT 2023
+ +C++VL K D+ ++ N + + + + ++ V
Sbjct: 1504 RFPANCAFVLSTICQKLPDISFQLIINFDKWSAPNLTIISPVYFYINEEQILINDRNTVK 1563
Query: 2024 VNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHLGHIFTFTPQNNEFQLQLSPKTFASKTYG 2083
VNG V+VP++ G + +Y + V + I + N ++ +S + +K G
Sbjct: 1564 VNGTQVNVPFITG-LATKIYSSEGFLV-IDTSPDIQIYYNGFNVIKISISER-LQNKVCG 1620
Query: 2084 LCGICDENGANDFMLRDGTVTTDWKTLVQEWTV----QRP-GQTCQPI-LEEQCLVPDSS 2137
LCG + + +D++ G L Q W +RP +C + + + D+
Sbjct: 1621 LCGNFNGDLTDDYVTLRGKPVVSSVVLAQSWKTNGMQKRPLAPSCNELQFSQYAAMCDNV 1680
Query: 2138 HCQVL-----------LLPLFAECHKVLAPATFYAICQQDSCHQE---QVCEVIASYAHL 2183
H Q + + F C+ +L P FY C D C+ Q+C +A+Y
Sbjct: 1681 HIQKMQGDGYCLKLTDMKGFFQPCYGLLDPLPFYESCYLDGCYSHKKFQLCGSLAAYGEA 1740
Query: 2184 CRTNGV-CVDWRTPDFCA 2200
CR+ G+ +W + C+
Sbjct: 1741 CRSFGILSTEWIEKENCS 1758
>gi|239755776 PREDICTED: similar to Mucin-19 [Homo sapiens]
Length = 1950
Score = 249 bits (636), Expect = 3e-65
Identities = 153/494 (30%), Positives = 226/494 (45%), Gaps = 35/494 (7%)
Query: 265 CPALLEYARTCAQEGMVLY-GWTDHS--ACSPV-CPAGMEYRQCVSPCARTCQSLHINEM 320
C E +R CA +G + W S C CP Y++C TC + +
Sbjct: 706 CDTYSELSRLCASDGPGTFESWRSDSDVVCETQRCPEQHIYKECGPSNPATCSN--VAPF 763
Query: 321 CQERCVDGCSCPEGQLLDE----GLCVESTECPCVHSGKRYPPGTSLSRDCNT-CICRNS 375
CV GC+CPEG LLD+ G CV ECPC SG Y PG C + C C+++
Sbjct: 764 QDSECVSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPGEVREGPCGSQCTCQDA 823
Query: 376 QWICSNEECPGECLVTGQSHFKSFDNRYFTFSGICQYLLARDCQDHSFSIVIETVQCADD 435
+W C+ CPG C V G S +FD + F G C +L + +SI +E C
Sbjct: 824 KWSCTEALCPGRCKVEGSS-LTTFDGVKYNFPGNCHFLAV---HNEDWSISVELRPCPSG 879
Query: 436 RDAVCTRSVTVRLPGLHNSLVKL-----KHGAGVAMDGQDVQLPLLKGDLRIQHTVTA-- 488
+ C SVT+ L NS V + V D Q ++I + ++
Sbjct: 880 QTGTCLNSVTLLL----NSSVPVDKYVFNSDGTVTNDKIRNQGYYYSDKIQIFNASSSYL 935
Query: 489 SVRLSYGEDLQMDWDGRGRLLVKLSPVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVED 548
V + LQ+ +L V + P T GLCG+YN DDF++ + E +
Sbjct: 936 QVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQA 995
Query: 549 FGNAWKLHGDCQDLQKQHSDPCALNPRMTRFSEEACAVL--TSPTFEACHRAVSPLPYLR 606
F N+W++ K + C ++ +F+E C +L +S +CH V+P PY
Sbjct: 996 FANSWEM----MSCPKGNPSSC-ISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHE 1050
Query: 607 NCRYDVCSCSDGRECLCGALASYAAACAGRGVRVAWREPGRCELNCPKGQVYLQCGTPCN 666
C+ C+C + ++CLC L +Y ACA + + G CE +CP G V+ CN
Sbjct: 1051 ECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEHSCPSGLVFKYNVKACN 1110
Query: 667 LTCRSLSYPDEECN--EACLEGCFCPPGLYMDERGDCVPKAQCPCYYDGEIFQPEDIFSD 724
+CRSLS D C+ + ++GC CP +Y + G+CV K+QC CY + E+ QP +
Sbjct: 1111 SSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHT 1170
Query: 725 HHTMCYCEDGFMHC 738
C C DG + C
Sbjct: 1171 DDNKCVCRDGILLC 1184
Score = 179 bits (455), Expect = 3e-44
Identities = 192/740 (25%), Positives = 293/740 (39%), Gaps = 115/740 (15%)
Query: 34 RCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRSFSIIGDF------QNGKRV-SLSV 86
RC + GS + TFDG Y+F G C +L +SI + Q G + S+++
Sbjct: 835 RCKVEGSS-LTTFDGVKYNFPGNCHFLAV---HNEDWSISVELRPCPSGQTGTCLNSVTL 890
Query: 87 YLGEFFDIHLFV---NGTVTQGDQRVSMPYASKGLYLETEAGYYKLSGEAYGFVA---RI 140
L + +V +GTVT R Y S + + + Y L E Y V +I
Sbjct: 891 LLNSSVPVDKYVFNSDGTVTNDKIRNQGYYYSDKIQIFNASSSY-LQVETYFHVKLQIQI 949
Query: 141 DGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGEQWC 200
V + F T GLCG++N AEDDFM+ + L FANSW + S C
Sbjct: 950 VPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMS----C 1005
Query: 201 ERASPPSSSCNISSGEMQKGLWEQCQ-LLKSTSVFARCHPLVDPEPFVALCEKTLCECAG 259
+ +P SSC S E +K C LL S+ A CHP+V+P+P+ C+K C C
Sbjct: 1006 PKGNP--SSC--ISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCEN 1061
Query: 260 GLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCARTCQSLHINE 319
+C C L Y + CA++ + GW C CP+G+ ++ V C +C+SL +
Sbjct: 1062 SQDCLCTILGNYVKACAEKETYIVGWRT-GLCEHSCPSGLVFKYNVKACNSSCRSLSERD 1120
Query: 320 M---CQERCVDGCSCPEGQLL-DEGLCVESTECPCVHSGKRYPPGTSLSRDCNTCICRNS 375
++ VDGC+CP+ +EG CV ++C C + + PG + D N C+CR+
Sbjct: 1121 RSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHTDDNKCVCRDG 1180
Query: 376 QWIC------SNEECPG--ECLVTGQSHFKSFDNRYFTFSGICQYLLARDCQDHSFSIVI 427
+C + + C G E + + NR + I + ++ +F I+
Sbjct: 1181 ILLCQIPIDLTLQNCSGGAEYVDCSDPKAQRRTNRTCSTRNIPVFDDYCGHENGTFRILT 1240
Query: 428 ETVQCADDRDAVCTRSVTVRLPGLHNSLVKLKHGAGVAMDGQDVQLPLLKGDLRIQHTVT 487
E+V C +D C+R + V G L +G LK D +++
Sbjct: 1241 ESVPCCED-GLTCSRKIIVAFQGKVCGLCGNNNGD-------------LKDDFTTRYSSV 1286
Query: 488 ASVRLSYGEDLQMDWDGRGRLLVKLSPVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVE 547
AS L +G W KT C + T +
Sbjct: 1287 ASGALEFGN----SW----------------KTSQECSD----------TVAQTFPCDSN 1316
Query: 548 DFGNAWKLHGDCQDLQKQHSDPCALNPRMTRFS----EEACAVLTSPTFEACHRAVSPLP 603
+ AW + C+ L+ C + + EEACA + AV+
Sbjct: 1317 PYCKAWAVR-KCEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVA--M 1373
Query: 604 YLRNCRYDVCSCSDGRECLCGALASYAAACAGRGVRVAWREPGRCELNCPKGQVYLQCGT 663
Y C S + LC Y + PG C + Y CGT
Sbjct: 1374 YAEACSAVGVCVSWRKPNLCPVYCDY------------YNAPGECRWH------YEPCGT 1415
Query: 664 PCNLTCRSLSYPDEECNEACLEGCF--CPPGL-YMDERG-DCVPKAQCPCYYDGEIFQPE 719
TC+ + + LEGC+ CP Y+DE CV ++C C+Y+ I
Sbjct: 1416 VTAKTCKDQLVGQK--FSSLLEGCYAKCPDSAPYLDENTMKCVSLSECSCFYNDVIPAGG 1473
Query: 720 DIFSDHHTMCYCEDGFMHCT 739
I + CYC G + C+
Sbjct: 1474 VIEDNCGRTCYCIAGQLECS 1493
Score = 162 bits (411), Expect = 3e-39
Identities = 118/396 (29%), Positives = 159/396 (40%), Gaps = 68/396 (17%)
Query: 805 VSGCLCPPGMVRH-ENRCVALERCPCFHQGKEYAPGETVKIGCNTCVCRDRKWNCTDHVC 863
V GC CP M ++ E CV +C C+ + PG+ + N CVCRD C +
Sbjct: 1130 VDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHTDDNKCVCRDGILLCQIPI- 1188
Query: 864 DATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPGTFRILVGNKGCSHPSVKCKK 923
D T G +YV CS P K ++
Sbjct: 1189 DLTLQNCS---------------GGAEYV--------------------DCSDP--KAQR 1211
Query: 924 RVTILVEGGEIELFDGEVNVKRPMKDETHFEVVESGRYIILLLGKALSVVWDRHLSISVV 983
R I +FD E+G + IL + L+ S
Sbjct: 1212 RTNRTCSTRNIPVFDDYCGH-------------ENGTFRILTESVPCC---EDGLTCSRK 1255
Query: 984 LKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKVSSQCADT--RKVPLDS 1041
+ +Q KVCGLCGN +G +D T+ V ++FGNSWK S +C+DT + P DS
Sbjct: 1256 IIVAFQGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTVAQTFPCDS 1315
Query: 1042 SPATCHNNIMKQTMVDSSCRILTSDVFQDCNKLVDPEPYLDVCIYDTCSCESIGDCACFC 1101
+P + K C IL F+DC+ VDP Y DVCI + C+C+ G FC
Sbjct: 1316 NPYCKAWAVRK-------CEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFC 1368
Query: 1102 DTIAAYAHVCAQHGKVVTWRTATLCPQSCEERNLRENGYECEWRYNSCAPACQVTCQHPE 1161
+A YA C+ G V+WR LCP C+ N EC W Y C TC+
Sbjct: 1369 TAVAMYAEACSAVGVCVSWRKPNLCPVYCDYYNAPG---ECRWHYEPCGTVTAKTCKDQL 1425
Query: 1162 PLACPVQCVEGCHAHCP-PGKILDELLQTCVDPEDC 1196
+EGC+A CP LDE CV +C
Sbjct: 1426 VGQKFSSLLEGCYAKCPDSAPYLDENTMKCVSLSEC 1461
Score = 148 bits (373), Expect = 8e-35
Identities = 141/532 (26%), Positives = 216/532 (40%), Gaps = 77/532 (14%)
Query: 776 CPADNLRAE-GLECTKTCQNYDLECMSMGCVSGCLCPPGM----VRHENRCVALERCPCF 830
CP ++ E G TC N CVSGC CP G + + +CV CPC
Sbjct: 740 CPEQHIYKECGPSNPATCSNV-APFQDSECVSGCTCPEGYLLDDIGEKGKCVLKAECPCE 798
Query: 831 HQGKEYAPGETVKIGCNT-CVCRDRKWNCTDHVCDATCSTIGMAHYLTFDGLKYLFPGEC 889
G Y PGE + C + C C+D KW+CT+ +C C G + TFDG+KY FPG C
Sbjct: 799 SSGTVYQPGEVREGPCGSQCTCQDAKWSCTEALCPGRCKVEG-SSLTTFDGVKYNFPGNC 857
Query: 890 QYVLVQDYCGSNPGTFRILVGNKGC-SHPSVKCKKRVTILVEGG---EIELFDGEVNVKR 945
++ V + + I V + C S + C VT+L+ + +F+ + V
Sbjct: 858 HFLAVHN------EDWSISVELRPCPSGQTGTCLNSVTLLLNSSVPVDKYVFNSDGTV-- 909
Query: 946 PMKDETHFEVVESGRY------IILLLGKALSVVWDRHLSISVVLKQTYQEKV------- 992
T+ ++ G Y I L V H+ + + + Q V
Sbjct: 910 -----TNDKIRNQGYYYSDKIQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQF 964
Query: 993 ---CGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKVSSQCADTRKVPLDSSPATCHNN 1049
GLCG+++ +D SS +E+ F NSW++ S C +P++C +
Sbjct: 965 TDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMS-CP-------KGNPSSC-IS 1015
Query: 1050 IMKQTMVDSSCRIL--TSDVFQDCNKLVDPEPYLDVCIYDTCSCESIGDCACFCDTIAAY 1107
I K+ + C IL +S C+ +V+P+PY + C TC+CE+ D C C + Y
Sbjct: 1016 IEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQD--CLCTILGNY 1073
Query: 1108 AHVCAQ-HGKVVTWRTATLCPQSCEERNLRENGYECEWRYNSCAPACQVTCQHPEPLACP 1166
CA+ +V WRT LC SC +G ++ +C +C+ +
Sbjct: 1074 VKACAEKETYIVGWRTG-LCEHSC------PSGLVFKYNVKACNSSCRSLSERDRSCDVE 1126
Query: 1167 VQCVEGCHAHCPPGKILDELLQTCVDPEDCPVCEVAGRRFASGKKVTLNPSDPEHCQICH 1226
V+GC P + CV C C + GK L +D C +C
Sbjct: 1127 DVPVDGCTC---PDAMYQNNEGNCVLKSQCD-CYINDEVMQPGK---LIHTDDNKC-VCR 1178
Query: 1227 -----CDV-VNLTCEACQEPGGLVVPPTDAPVSPTTLYVEDISEPPLHDFYC 1272
C + ++LT + C G V +D T P+ D YC
Sbjct: 1179 DGILLCQIPIDLTLQNC-SGGAEYVDCSDPKAQRRTNRTCSTRNIPVFDDYC 1229
Score = 94.0 bits (232), Expect = 2e-18
Identities = 115/480 (23%), Positives = 186/480 (38%), Gaps = 78/480 (16%)
Query: 1923 LRPSCPNSQS-----PVKVEE-----TCGC---RWTCP-------CVCTGSSTRHIVTFD 1962
L+ CP S P +V E C C +W+C C GSS + TFD
Sbjct: 791 LKAECPCESSGTVYQPGEVREGPCGSQCTCQDAKWSCTEALCPGRCKVEGSS---LTTFD 847
Query: 1963 GQNFKLTGSCSYVLFQNKEQDLEVILHNGACSPGARQGCMKSIEVK-HSALSVE---LHS 2018
G + G+C ++ N++ + V L C G C+ S+ + +S++ V+ +S
Sbjct: 848 GVKYNFPGNCHFLAVHNEDWSISVELR--PCPSGQTGTCLNSVTLLLNSSVPVDKYVFNS 905
Query: 2019 DMEVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHLGHIFTFTPQNNEFQLQLS-PKTF 2077
D VT N ++ + Y + ++ ++ A ++ H+ QL +S P
Sbjct: 906 DGTVT-NDKIRNQGYYYSD-KIQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQ 963
Query: 2078 ASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTVQRPGQTCQPILEEQCLVPDSS 2137
+ T GLCG + +DFM + + W + +C C+ +
Sbjct: 964 FTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMM----SCPKGNPSSCISIEKE 1019
Query: 2138 -----HCQVLLL---PLFAECHKVLAPATFYAICQQDSC----HQEQVCEVIASYAHLCR 2185
HC +LL PL A CH ++ P ++ C++ +C Q+ +C ++ +Y C
Sbjct: 1020 KFAERHCGILLDSSGPL-ASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACA 1078
Query: 2186 TNGV-CVDWRTPDFCAMSCPPSLVYNHCEHGCPRHC---DGNVSSCG--DHPSEGCFCPP 2239
V WRT C SCP LV+ + C C SC D P +GC CP
Sbjct: 1079 EKETYIVGWRT-GLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPD 1137
Query: 2240 DKVM-LEGSCVPEEACTQCIGEDGVQHQFLEAWVPDHQPCQICTCLSGRKVNCTTQPC-- 2296
EG+CV + C I ++ +Q L + C+ L ++ T Q C
Sbjct: 1138 AMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHTDDNKCVCRDGILLCQIPIDLTLQNCSG 1197
Query: 2297 ---------PTAKAPTCGLCEVARLRQNADQCCPE---YECVCDPVSCDLPPVPHCERGL 2344
P A+ T C + D C E + + + V C CE GL
Sbjct: 1198 GAEYVDCSDPKAQRRTNRTCSTRNIPVFDDYCGHENGTFRILTESVPC-------CEDGL 1250
Score = 77.4 bits (189), Expect = 2e-13
Identities = 48/152 (31%), Positives = 71/152 (46%), Gaps = 15/152 (9%)
Query: 604 YLRNCRYDVCSCSDGRECLCGALASYAAACA--GRGVRVAWREPGR--CELN-CPKGQVY 658
Y C + C D + C + + CA G G +WR CE CP+ +Y
Sbjct: 688 YKMICIDEYCQTRD-KTSTCDTYSELSRLCASDGPGTFESWRSDSDVVCETQRCPEQHIY 746
Query: 659 LQCGTPCNLTCRSLS-YPDEECNEACLEGCFCPPGLYMD---ERGDCVPKAQCPCYYDGE 714
+CG TC +++ + D EC + GC CP G +D E+G CV KA+CPC G
Sbjct: 747 KECGPSNPATCSNVAPFQDSEC----VSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGT 802
Query: 715 IFQPEDIFSDH-HTMCYCEDGFMHCTMSGVPG 745
++QP ++ + C C+D CT + PG
Sbjct: 803 VYQPGEVREGPCGSQCTCQDAKWSCTEALCPG 834
Score = 67.4 bits (163), Expect = 2e-10
Identities = 43/170 (25%), Positives = 67/170 (39%), Gaps = 19/170 (11%)
Query: 2077 FASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTVQRP-----GQTCQPILEEQC 2131
F K GLCG + + +DF R +V + W + QT C
Sbjct: 1260 FQGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTVAQTFPCDSNPYC 1319
Query: 2132 LVPDSSHCQVLLLPLFAECHKVLAPATFYAICQQDSCHQEQ------VCEVIASYAHLCR 2185
C++L F +CH + P+ ++ +C +++C + C +A YA C
Sbjct: 1320 KAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACS 1379
Query: 2186 TNGVCVDWRTPDFCAMSCPPSLVYNHCEHGCPRHCDGNVSSCGDHPSEGC 2235
GVCV WR P+ C + C YN P C + CG ++ C
Sbjct: 1380 AVGVCVSWRKPNLCPVYCD---YYN-----APGECRWHYEPCGTVTAKTC 1421
Score = 42.7 bits (99), Expect = 0.005
Identities = 43/163 (26%), Positives = 59/163 (36%), Gaps = 20/163 (12%)
Query: 2149 ECHKVLAPATFYA-ICQQDSCH---QEQVCEVIASYAHLCRTNG--VCVDWRTPD--FC- 2199
+C KV A + Y IC + C + C+ + + LC ++G WR+ C
Sbjct: 677 KCGKVAALSNDYKMICIDEYCQTRDKTSTCDTYSELSRLCASDGPGTFESWRSDSDVVCE 736
Query: 2200 AMSCPPSLVYNHCEHGCPRHCDGNVSSCGDHPSEGCFCPP----DKVMLEGSCVPEEACT 2255
CP +Y C P C GC CP D + +G CV + C
Sbjct: 737 TQRCPEQHIYKECGPSNPATCSNVAPFQDSECVSGCTCPEGYLLDDIGEKGKCVLKAECP 796
Query: 2256 QCIGEDGVQHQFLEAWVPDHQPC-QICTCLSGRKVNCTTQPCP 2297
G +Q E PC CTC K +CT CP
Sbjct: 797 --CESSGTVYQPGEV---REGPCGSQCTC-QDAKWSCTEALCP 833
Score = 32.7 bits (73), Expect = 5.2
Identities = 18/65 (27%), Positives = 28/65 (43%), Gaps = 1/65 (1%)
Query: 386 GECLVTGQSHFKSFDNRYFTFSGICQYLLARDCQDHSFSIVIETVQCADDRDAVCTRSVT 445
GE + +KSF+ R F F C Y R C + IE ++ +DR +
Sbjct: 595 GEISTWSKGAYKSFNGRIFFFESSCPYTFCRHCIESGGDFNIE-IKRNNDRQDINEHIAN 653
Query: 446 VRLPG 450
++PG
Sbjct: 654 SKIPG 658
>gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens]
Length = 1503
Score = 226 bits (575), Expect = 3e-58
Identities = 146/449 (32%), Positives = 196/449 (43%), Gaps = 56/449 (12%)
Query: 307 PCARTCQSLHINEMCQERCVDGCSCPEGQL-LDEGLCVESTECP---CVHSGKRYPPGTS 362
PC TCQ + +C + SCP + G C P CVH G+ G
Sbjct: 1040 PCY-TCQCQDLTWLCIHQACPELSCPLSERHTPPGSCCPVCRAPTQSCVHQGREVASGER 1098
Query: 363 LSRD-CNTCICRNSQWICSNEEC-------------------------PGECLVTGQSHF 396
+ D C +C C C ++ C P C+ G H+
Sbjct: 1099 WTVDTCTSCSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRCLPRPASCMAFGDPHY 1158
Query: 397 KSFDNRYFTFSGICQYLLARDCQDHSFSIVIETVQCADDRD---AVCTRSVTVRLPGLHN 453
++FD R F G C Y+LA+DC FS+ + DDR T+ V V L +
Sbjct: 1159 RTFDGRLLHFQGSCSYVLAKDCHSGDFSVHVTN----DDRGRSGVAWTQEVAVLLGDM-- 1212
Query: 454 SLVKLKHGAGVAMDGQDVQLPLLKGDLRIQHTVTASVRLSYGEDLQMDWDGRGRLLVKLS 513
V+L V +DG V LP L+ L +V L LQ+ WDG+ ++ V +
Sbjct: 1213 -AVRLLQDGAVTVDGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSVP 1271
Query: 514 PVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWKLHGDCQDLQK----QHSDP 569
Y G+TCGLCGN+NG DD P GL P FGN+W++ + + DP
Sbjct: 1272 GSYQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGRPCSAGREVDP 1331
Query: 570 C-ALNPRMTRFSEEACAVLTSPTFEACHRAVSPLPYLRNCRYDVCSCSDGRE---CLCGA 625
C A R R + C VL S F CH V P P+ C YD+C+C G CLC A
Sbjct: 1332 CRAAGYRARREANARCGVLKSSPFSRCHAVVPPEPFFAACVYDLCACGPGSSADACLCDA 1391
Query: 626 LASYAAACAGRGVRVAWREPGRCELNCP--KGQVYLQCGTPCNLTCRSLSYPDEE----C 679
L +YA+ C GV WR P C + CP +G V+ +CG PC TC + P E C
Sbjct: 1392 LEAYASHCRQAGVTPTWRGPTLCVVGCPLERGFVFDECGPPCPRTCFNQHIPLGELAAHC 1451
Query: 680 NEACLEGCFCPPGLYMDERGDCVPKAQCP 708
C+ GC CP GL ++ C+P CP
Sbjct: 1452 VRPCVPGCQCPAGL-VEHEAHCIPPEACP 1479
Score = 195 bits (496), Expect = 5e-49
Identities = 206/712 (28%), Positives = 267/712 (37%), Gaps = 145/712 (20%)
Query: 595 CHRAVSPLPYLRNCRYDVC-SC-SDGRE------------------CLCGALASYAAACA 634
C A+ P P C VC SC S GRE C G ++ C
Sbjct: 816 CPPALCPHPSPGPCFCPVCHSCLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCVRLQCP 875
Query: 635 GRGVRVAWREPGRCELNCPKGQVYLQCGTPCNLTCRSLSYPDEECNEACLEGCFCPPGLY 694
++ E G C CP+ + L G R + PD C+ C C G+
Sbjct: 876 PLPCKLQVTERGSC---CPRCRGCLAHGEEHPEGSRWVP-PDSACSS-----CVCHEGVV 926
Query: 695 MDERGDCV---------PKAQCP----CYYDGEIFQPEDIF---SDHHTMCYCEDGFMHC 738
R C+ P CP C ++G ++P + F +D +C CE
Sbjct: 927 TCARIQCISSCAQPRQGPHDCCPQCSDCEHEGRKYEPGESFQPGADPCEVCICEPQ---- 982
Query: 739 TMSGVPGSLLPDAVLSSPLSHRSKRSLSCRPPMVKL------VCP--ADNLR--AEGLEC 788
P+ S R SL PP L CP A+ L +EGL
Sbjct: 983 ----------PEGPPSLRCHRRQCPSLVGCPPSQLLPPGPQHCCPTCAEALSNCSEGLLG 1032
Query: 789 TK--------TCQNYDLE--CMSMGCVSGCLCPPGMVRHE--NRCVALERCP---CFHQG 833
++ TCQ DL C+ C L P RH C + R P C HQG
Sbjct: 1033 SELAPPDPCYTCQCQDLTWLCIHQACPE--LSCPLSERHTPPGSCCPVCRAPTQSCVHQG 1090
Query: 834 KEYAPGETVKIG-CNTCVCRDRKWNCTDHVCD-------------------------ATC 867
+E A GE + C +C C C C A+C
Sbjct: 1091 REVASGERWTVDTCTSCSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRCLPRPASC 1150
Query: 868 STIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPGTFRILVGNKGCSHPSVKCKKRVTI 927
G HY TFDG F G C YVL +D C S G F + V N V + V +
Sbjct: 1151 MAFGDPHYRTFDGRLLHFQGSCSYVLAKD-CHS--GDFSVHVTNDDRGRSGVAWTQEVAV 1207
Query: 928 LVEGGEIELF-DGEVNVKR-----PMKDETHFEVVESGRYIILLLGKALSVVWDRHLSIS 981
L+ + L DG V V P E V G +IL L V+WD +
Sbjct: 1208 LLGDMAVRLLQDGAVTVDGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLWDGQSQVE 1267
Query: 982 VVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKVSSQCADTRKVPLDS 1041
V + +YQ + CGLCGNF+G +DL + FGNSW+VS R
Sbjct: 1268 VSVPGSYQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGRPCSAGR 1327
Query: 1042 SPATCH-NNIMKQTMVDSSCRILTSDVFQDCNKLVDPEPYLDVCIYDTCSC--ESIGDCA 1098
C + ++ C +L S F C+ +V PEP+ C+YD C+C S D A
Sbjct: 1328 EVDPCRAAGYRARREANARCGVLKSSPFSRCHAVVPPEPFFAACVYDLCACGPGSSAD-A 1386
Query: 1099 CFCDTIAAYAHVCAQHGKVVTWRTATLCPQSCEERNLRENGYECEWRYNSCAPACQVTC- 1157
C CD + AYA C Q G TWR TLC C E G+ ++ C P C TC
Sbjct: 1387 CLCDALEAYASHCRQAGVTPTWRGPTLCVVGCP----LERGFV----FDECGPPCPRTCF 1438
Query: 1158 -QHPEPLA-----CPVQCVEGCHAHCPPGKILDELLQTCVDPEDCPVCEVAG 1203
QH PL C CV GC CP G + E C+ PE CP + G
Sbjct: 1439 NQH-IPLGELAAHCVRPCVPGC--QCPAGLVEHE--AHCIPPEACPQVLLTG 1485
Score = 179 bits (454), Expect = 3e-44
Identities = 123/353 (34%), Positives = 159/353 (45%), Gaps = 26/353 (7%)
Query: 18 PGTLCAEGTRGRSSTARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRSFSI--IGD 75
PG+ C R A C FG TFDG + F G CSY+LA C FS+ D
Sbjct: 1136 PGSCCP---RCLPRPASCMAFGDPHYRTFDGRLLHFQGSCSYVLAKDCHSGDFSVHVTND 1192
Query: 76 FQNGKRVS----LSVYLGEFFDIHLFVNGTVTQGDQRVSMPYASKGLYLETEAGYYKLSG 131
+ V+ ++V LG+ + L +G VT V++P+ + L G+ +
Sbjct: 1193 DRGRSGVAWTQEVAVLLGDMA-VRLLQDGAVTVDGHPVALPFLQEPLLYVELRGHTVILH 1251
Query: 132 EAYGFVARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSW 191
G DG +V + Y +TCGLCGNFN FA+DD EG L F NSW
Sbjct: 1252 AQPGLQVLWDGQSQVEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSW 1311
Query: 192 ALSSGEQWCER---ASPPSSSCNISSGEMQKGLWEQCQLLKSTSVFARCHPLVDPEPFVA 248
+S G W R A C + ++ +C +LKS S F+RCH +V PEPF A
Sbjct: 1312 QVSEG-LWPGRPCSAGREVDPCRAAGYRARREANARCGVLKS-SPFSRCHAVVPPEPFFA 1369
Query: 249 LCEKTLCECAGGLE---CACPALLEYARTCAQEGMVLYGWTDHSACSPVCP--AGMEYRQ 303
C LC C G C C AL YA C Q G V W + C CP G + +
Sbjct: 1370 ACVYDLCACGPGSSADACLCDALEAYASHCRQAG-VTPTWRGPTLCVVGCPLERGFVFDE 1428
Query: 304 CVSPCARTCQSLHI--NEM---CQERCVDGCSCPEGQLLDEGLCVESTECPCV 351
C PC RTC + HI E+ C CV GC CP G + E C+ CP V
Sbjct: 1429 CGPPCPRTCFNQHIPLGELAAHCVRPCVPGCQCPAGLVEHEAHCIPPEACPQV 1481
Score = 122 bits (305), Expect = 7e-27
Identities = 114/427 (26%), Positives = 173/427 (40%), Gaps = 61/427 (14%)
Query: 1871 LCSGFVRICMDEDGNEKRPGDVWTLPDQCHTVTCQPDGQTLLKSHRVNCDRGLRPSCPNS 1930
+C + C+ + G E G+ WT+ D C + +C G +S R + SC
Sbjct: 1078 VCRAPTQSCVHQ-GREVASGERWTV-DTCTSCSCMA-GTVRCQSQRCS-----PLSCGPD 1129
Query: 1931 QSPVKVEETCGCRWTC-PCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKEQ-DLEVIL 1988
++P +C R P C H TFDG+ GSCSYVL ++ D V +
Sbjct: 1130 KAPALSPGSCCPRCLPRPASCMAFGDPHYRTFDGRLLHFQGSCSYVLAKDCHSGDFSVHV 1189
Query: 1989 HNGACSPGARQGCM--KSIEVKHSALSVELHSDMEVTVNGRLVSVPYVGGNMEVNVYGAI 2046
N R G + + V ++V L D VTV+G V++P++ + +
Sbjct: 1190 TN---DDRGRSGVAWTQEVAVLLGDMAVRLLQDGAVTVDGHPVALPFLQEPL-------L 1239
Query: 2047 MHEVRFNHLGHIFTFTPQ-------NNEFQLQLS-PKTFASKTYGLCGICDENGANDFML 2098
E+R GH Q + + Q+++S P ++ +T GLCG + +D
Sbjct: 1240 YVELR----GHTVILHAQPGLQVLWDGQSQVEVSVPGSYQGRTCGLCGNFNGFAQDDLQG 1295
Query: 2099 RDGTVTTDWKTLVQEWTVQR---PGQTCQPILE-EQCLVPD-------SSHCQVLLLPLF 2147
+G + W V PG+ C E + C ++ C VL F
Sbjct: 1296 PEGLLLPSEAAFGNSWQVSEGLWPGRPCSAGREVDPCRAAGYRARREANARCGVLKSSPF 1355
Query: 2148 AECHKVLAPATFYAICQQDSCH-------QEQVCEVIASYAHLCRTNGVCVDWRTPDFCA 2200
+ CH V+ P F+A C D C +C+ + +YA CR GV WR P C
Sbjct: 1356 SRCHAVVPPEPFFAACVYDLCACGPGSSADACLCDALEAYASHCRQAGVTPTWRGPTLCV 1415
Query: 2201 MSCP--PSLVYNHCEHGCPRHCDGNVSSCGDHPSE-------GCFCPPDKVMLEGSCVPE 2251
+ CP V++ C CPR C G+ + GC CP V E C+P
Sbjct: 1416 VGCPLERGFVFDECGPPCPRTCFNQHIPLGELAAHCVRPCVPGCQCPAGLVEHEAHCIPP 1475
Query: 2252 EACTQCI 2258
EAC Q +
Sbjct: 1476 EACPQVL 1482
Score = 103 bits (257), Expect = 2e-21
Identities = 117/456 (25%), Positives = 166/456 (36%), Gaps = 83/456 (18%)
Query: 2220 CDGNVSSCGDHPSE--GCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWVPDHQP 2277
C G +CG P E GC P ++ G C P C C GV E P
Sbjct: 744 CLGGFVTCGRRPCEPPGCSHP---LIPSGHCCP--TCQGC-RYHGVTTASGETLPDPLDP 797
Query: 2278 -CQICTCLSGRKVNCTTQPCPTAKAPT-------CGLCEVARLRQNADQCCPEYE----- 2324
C +CTC G + C +PCP A P C +C + Q E+E
Sbjct: 798 TCSLCTCQEG-SMRCQKKPCPPALCPHPSPGPCFCPVCHSCLSQGREHQDGEEFEGPAGS 856
Query: 2325 -----CVCDPVSC---DLPPVPHCERGLQPTLTNPGECRPNFT-CACRKEECKRVSPPSC 2375
C VSC PP+P C+ LQ +T G C P C EE S
Sbjct: 857 CEWCRCQAGQVSCVRLQCPPLP-CK--LQ--VTERGSCCPRCRGCLAHGEEHPEGSR-WV 910
Query: 2376 PPHRLPTLRKTQCCDEYECACNCVNSTVSCPLGYLASTATNDCGCTTTTCLPDKVCVHRS 2435
PP D +C C V+C S+ C C H
Sbjct: 911 PP------------DSACSSCVCHEGVVTCARIQCISSCAQPRQGPHDCCPQCSDCEHEG 958
Query: 2436 TIYPVGQFWEEG---CDVCTCTDMEDAVMGLRVAQCSQKPCEDSCRSGFTYVLHEGECCG 2492
Y G+ ++ G C+VC C + LR C ++ C + +L G
Sbjct: 959 RKYEPGESFQPGADPCEVCICEPQPEGPPSLR---CHRRQCPSLVGCPPSQLLPPGP--Q 1013
Query: 2493 RCLPSACEVVTGSPRGDSQSSWKSVGSQWASPENPCLINECVRVKEEVFIQQRNVSCPQL 2552
C P+ E ++ G +GS+ A P+ PC +C + Q +CP+L
Sbjct: 1014 HCCPTCAEALSNCSEG-------LLGSELAPPD-PCYTCQCQDLTWLCIHQ----ACPEL 1061
Query: 2553 EVPVCPSGFQLSCKTSACCPSCRCERMEACMLNGTVIGPGKTVMIDVCTTCRCMVQVGVI 2612
P+ + +CCP CR ++C+ G + G+ +D CT+C CM
Sbjct: 1062 SCPLS----ERHTPPGSCCPVCRAPT-QSCVHQGREVASGERWTVDTCTSCSCMAGT--- 1113
Query: 2613 SGFKLECRKTTCNPCPLGYKEEN--NTGECCGRCLP 2646
+ C+ C+P G + + G CC RCLP
Sbjct: 1114 ----VRCQSQRCSPLSCGPDKAPALSPGSCCPRCLP 1145
Score = 79.3 bits (194), Expect = 5e-14
Identities = 125/543 (23%), Positives = 176/543 (32%), Gaps = 158/543 (29%)
Query: 2239 PDKVMLEGSCVPEEACTQCIGEDGVQH-QFLEAWVPDHQPCQICTCLSGRKVNCTTQPCP 2297
P+ V+L G C P+ G H + E + P PC+ C CL G V+C PCP
Sbjct: 585 PEPVLLPGECCPQCPAPAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDG-SVSCQRLPCP 643
Query: 2298 TAKAPTCGLCEVARLRQNADQCCPEYECVCDPVSCDLPPVPHCERGLQPTLTNPGECRPN 2357
A A RQ CCP SCD C Q GE P+
Sbjct: 644 PAPC--------AHPRQG--PCCP---------SCD-----GCL--YQGKEFASGERFPS 677
Query: 2358 FTCACRKEECKRVS----PPSCPPHRLPTLRKTQCCDEYE-C------------------ 2394
T AC C S P +C P P + CC + + C
Sbjct: 678 PTAACHLCLCWEGSVSCEPKACAPALCPFPARGDCCPDCDGCEYLGESYLSNQEFPDPRE 737
Query: 2395 ---ACNCVNSTVSC---------------PLGYLASTATNDC---GCTTTT--CLPDKVC 2431
C C+ V+C P G+ T C G TT + LPD +
Sbjct: 738 PCNLCTCLGGFVTCGRRPCEPPGCSHPLIPSGHCCPTC-QGCRYHGVTTASGETLPDPL- 795
Query: 2432 VHRSTIYPVGQFWEEGCDVCTCTDMEDAVMGLRVAQCSQKPCEDSCRSGFTYVLHEGECC 2491
+ C +CTC + +C +KPC + L
Sbjct: 796 -------------DPTCSLCTCQEGS--------MRCQKKPCPPA--------LCPHPSP 826
Query: 2492 GRCLPSACEVVTGSPRGDSQSSWKSVGSQWASPENPCLINECVRVKEEVFIQQRNVSCPQ 2551
G C C SQ G ++ P C C Q VSC +
Sbjct: 827 GPCFCPVCHSCL------SQGREHQDGEEFEGPAGSCEWCRC---------QAGQVSCVR 871
Query: 2552 LEVPVCPSGFQLSCKTSACCPSCRCERMEACMLNGTVIGPGKTVMIDVCTTCRCMVQVGV 2611
L+ P P Q++ + +CCP CR C+ +G G + C+ GV
Sbjct: 872 LQCPPLPCKLQVT-ERGSCCPRCR-----GCLAHGEEHPEGSRWVPPDSACSSCVCHEGV 925
Query: 2612 ISGFKLECRKTTCNPCPLGYKEENNTGECCGRCLPTACTIQLRGGQIMTLKRDETLQDG- 2670
++ +++C + P +CC +C + C + R + E+ Q G
Sbjct: 926 VTCARIQCISSCAQP-------RQGPHDCCPQC--SDCEHEGR-----KYEPGESFQPGA 971
Query: 2671 --CDTHFCKVNERGEYFWE------KRVTGCPPFDEHKCLAEGGKIMKIPGTCCDTCEEP 2722
C+ C+ G + GCPP + L G P CC TC E
Sbjct: 972 DPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPP---SQLLPPG------PQHCCPTCAEA 1022
Query: 2723 ECN 2725
N
Sbjct: 1023 LSN 1025
Score = 77.8 bits (190), Expect = 1e-13
Identities = 122/545 (22%), Positives = 166/545 (30%), Gaps = 142/545 (26%)
Query: 2196 PDFC--------AMSCPPSLVYNHCEHGCPRHCD--GNVSSCGDHPSEGCFCPPDKVMLE 2245
PD C A C P HC GC ++ GN + C C V +
Sbjct: 111 PDACTACVCQDGAAHCGPQAHLPHCR-GCSQNGQTYGNGETFSPDACTTCRCLTGAVQCQ 169
Query: 2246 G----------SCVPE-EACTQCIGEDGVQHQFLEAWVPDHQPCQICTCLSG----RKVN 2290
G SC P E C C E G + + W PC+IC CL G R+
Sbjct: 170 GPSCSELNCLESCTPPGECCPICCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRE 229
Query: 2291 CTT------QPCPTAKAPTCGLCEVARLRQ-------NADQC----CPEYECVCDPVSCD 2333
C + +P P P C C + + D C C C+P+ C
Sbjct: 230 CASLCPYPARPLPGTCCPVCDGCFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEPLPC- 288
Query: 2334 LPPVPHCERGLQPTLTNPGECRP-------------------------NFTCACRKEECK 2368
PPVP G PG+C P C+C+ E
Sbjct: 289 -PPVPCRHPG-----KIPGQCCPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVS 342
Query: 2369 RVSPPSCP--PHRLPTLRKTQC--CD----------EYE------CACNCVNSTVSCPLG 2408
CP P LP + C C+ ++E AC C + C
Sbjct: 343 -CEEQECPVTPCALPASGRQLCPACELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAV 401
Query: 2409 YLASTATNDCGCTTTTCLPD-KVCVHRSTIYPVGQFWEEGCDVCTCTDMEDAVMGLRVAQ 2467
C P C + S +Y GQ + + C +D + +
Sbjct: 402 LCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDADSPCHACHCQDGTVTCSLVD 461
Query: 2468 CSQKPCEDSCRSGFTYVLHEGECCGRCLPSACEVVTGSPRGDSQSSWKSVGSQWASPENP 2527
C C +SG G+CC RC P + G ++ P +P
Sbjct: 462 CPPTTCARP-QSG------PGQCCPRC-----------PDCILEEEVFVDGESFSHPRDP 503
Query: 2528 CLINECVRVKEEVFIQQRNVSCPQLEVPVCPSGFQLSCKTSACCPSCRCERMEACMLNGT 2587
C +E Q+ + C P P L CCP+ C G
Sbjct: 504 C---------QECRCQEGHAHCQPRPCPRAPCAHPL---PGTCCPN----DCSGCAFGGK 547
Query: 2588 VIGPGKTV--MIDVCTTCRCMVQVGVISGFKLECRKTTCNPCPLGYKEENNTGECCGRC- 2644
G D C CRC +SG ++C C P P + GECC +C
Sbjct: 548 EYPSGADFPHPSDPCRLCRC------LSG-NVQCLARRCVPLPCP-EPVLLPGECCPQCP 599
Query: 2645 LPTAC 2649
P C
Sbjct: 600 APAGC 604
Score = 67.0 bits (162), Expect = 2e-10
Identities = 108/457 (23%), Positives = 158/457 (34%), Gaps = 95/457 (20%)
Query: 2224 VSSCGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWVPDHQPCQICTC 2283
+ SC HP+ + EG+ +ACT C+ +DG H +A +P + C
Sbjct: 84 LESCECHPASPQCWGLGRAWPEGARWEPDACTACVCQDGAAHCGPQAHLPHCRGCSQNGQ 143
Query: 2284 LSGRKVNCTTQPCPTAKAPTCGL-CEVARLRQ--NADQCCPEYECVCDPVSCDLPPVPHC 2340
G + C T + T + C+ + + C P EC P+ C H
Sbjct: 144 TYGNGETFSPDACTTCRCLTGAVQCQGPSCSELNCLESCTPPGECC--PICC-TEGGSHW 200
Query: 2341 ERGLQPTLTNPGECRPNFTCACRKE--ECKRVSPPSCPPHRLPTLRKTQC--CD------ 2390
E G + T PG+ P C C + +C++ S P+ L T C CD
Sbjct: 201 EHGQE--WTTPGD--PCRICRCLEGHIQCRQRECASLCPYPARPLPGTCCPVCDGCFLNG 256
Query: 2391 -EYECA-----------CNCVNSTVSCPLGYLASTATNDCGCTTTTCLPDKVC------V 2432
E+ C C N +V C G C P VC
Sbjct: 257 REHRSGEPVGSGDPCSHCRCANGSVQCEPLPCPPVPCRHPGKIPGQCCP--VCDGCEYQG 314
Query: 2433 HRSTIYPVGQFWEEG-CDVCTCTDMEDAVMGLRVAQCSQKPCEDSCRSGFTYVLHEGECC 2491
H+ + E G C C+C E + +C PC
Sbjct: 315 HQYQSQETFRLQERGLCVRCSCQAGE---VSCEEQECPVTPC-------------ALPAS 358
Query: 2492 GRCLPSACEVVTGSPRGDSQSSWKSVGSQWASPENPCLINECVRVKEEVFIQQRNVSCP- 2550
GR L ACE+ D + + G QW PC C ++ + V CP
Sbjct: 359 GRQLCPACEL-------DGEEF--AEGVQWEPDGRPCTACVC----QDGVPKCGAVLCPP 405
Query: 2551 -QLEVPVCPSGFQLSCKTSACCPSCRCERMEACMLNGTVIGPGK--TVMIDVCTTCRCMV 2607
+ P P G ACCPSC ++C + V G+ T C C C
Sbjct: 406 APCQHPTQPPG--------ACCPSC-----DSCTYHSQVYANGQNFTDADSPCHACHC-- 450
Query: 2608 QVGVISGFKLECRKTTCNPCPLGYKEENNTGECCGRC 2644
Q G ++ ++C TTC + ++ G+CC RC
Sbjct: 451 QDGTVTCSLVDCPPTTC------ARPQSGPGQCCPRC 481
Score = 65.5 bits (158), Expect = 7e-10
Identities = 98/446 (21%), Positives = 141/446 (31%), Gaps = 123/446 (27%)
Query: 2431 CVHRSTIYPVGQ-FWEEGCDVCTCTDMEDAVMGLRVAQCSQKPCEDSCRSGFTYVLHEGE 2489
C Y G+ F + C C C G CS+ C +SC GE
Sbjct: 138 CSQNGQTYGNGETFSPDACTTCRCLTGAVQCQG---PSCSELNCLESCTP-------PGE 187
Query: 2490 CCGRCLPSACEVVTGSPRGDSQSSWKSVGSQWASPENPCLINECVRVKEEVFIQQRNVSC 2549
CC C + S W+ G +W +P +PC I C+ E IQ R C
Sbjct: 188 CCPICCT------------EGGSHWEH-GQEWTTPGDPCRICRCL----EGHIQCRQREC 230
Query: 2550 PQLEVPVCPSGFQLSCKTSACCPSCRCERMEACMLNGTVIGPGKTVMI-DVCTTCRCMVQ 2608
L CP + CCP C + C LNG G+ V D C+ CRC
Sbjct: 231 ASL----CP--YPARPLPGTCCPVC-----DGCFLNGREHRSGEPVGSGDPCSHCRC--- 276
Query: 2609 VGVISGFKLECRKTTCNPCPLGYKEENNTGECCGRCLPTACTIQLRGGQIMTLKRDETLQ 2668
+ ++C C P P + G+ G+C P + +G Q + + +
Sbjct: 277 ----ANGSVQCEPLPCPPVPC-----RHPGKIPGQCCPVCDGCEYQGHQYQSQETFRLQE 327
Query: 2669 DG-CDTHFCKVNERGEYFWEKRVTGC--PPFDEHKC---------LAEG----------- 2705
G C C+ E E VT C P C AEG
Sbjct: 328 RGLCVRCSCQAGEVSCEEQECPVTPCALPASGRQLCPACELDGEEFAEGVQWEPDGRPCT 387
Query: 2706 -----------GKIM----------KIPGTCCDTCEEPECNDITARLQYVKVGSCKSEVE 2744
G ++ + PG CC P C+ T Q G ++ +
Sbjct: 388 ACVCQDGVPKCGAVLCPPAPCQHPTQPPGACC-----PSCDSCTYHSQVYANGQNFTDAD 442
Query: 2745 VDIHYCQGKCASKAMYSIDINDVQDQCSCCSPTRTEPMQVALHC----------TNGSVV 2794
H C + + +D + C+ ++ P Q C +G
Sbjct: 443 SPCHACHCQDGTVTCSLVDCPP-----TTCARPQSGPGQCCPRCPDCILEEEVFVDGESF 497
Query: 2795 YHEVLNAMECK-------CSPRKCSK 2813
H EC+ C PR C +
Sbjct: 498 SHPRDPCQECRCQEGHAHCQPRPCPR 523
Score = 50.8 bits (120), Expect = 2e-05
Identities = 45/168 (26%), Positives = 60/168 (35%), Gaps = 38/168 (22%)
Query: 2556 VCPSGFQLSCKTSACCPSCRCERMEACMLNGTVIGPGKTVMIDVCTTCRCMVQVGVISGF 2615
VC G C A P CR C NG G G+T D CTTCRC+
Sbjct: 118 VCQDG-AAHCGPQAHLPHCR-----GCSQNGQTYGNGETFSPDACTTCRCLTGA------ 165
Query: 2616 KLECRKTTCNPCPLGYKEENNTGECC---GRCLPTACTIQLRGGQIMTLKRDETLQDGCD 2672
++C+ +C+ E N E C G C P CT GG ++ T G
Sbjct: 166 -VQCQGPSCS--------ELNCLESCTPPGECCPICCT---EGGSHWEHGQEWT-TPGDP 212
Query: 2673 THFCKVNERGEYFWEKRVTGCPPFDEHKCLAEGGKIMKIPGTCCDTCE 2720
C+ E ++ P+ +PGTCC C+
Sbjct: 213 CRICRCLEGHIQCRQRECASLCPYPAR----------PLPGTCCPVCD 250
Score = 48.5 bits (114), Expect = 9e-05
Identities = 62/272 (22%), Positives = 90/272 (33%), Gaps = 41/272 (15%)
Query: 613 CSCSDGRECLCGALASYAAACAGRGVRVAWREPGRCELNCP----KGQVYLQCGTPCNLT 668
C C DG C + CA PG+C CP + +V++
Sbjct: 448 CHCQDGT-VTCSLVDCPPTTCAR-----PQSGPGQCCPRCPDCILEEEVFVDG------- 494
Query: 669 CRSLSYPDEECNEA-CLEG-CFCPPG------LYMDERGDCVPKAQCPCYYDGEIFQPED 720
S S+P + C E C EG C P G C P C + G+ +
Sbjct: 495 -ESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHPLPGTCCPNDCSGCAFGGKEYPSGA 553
Query: 721 IF---SDHHTMCYCEDGFMHCTMSGVPGSLLPDAVL-SSPLSHRSKRSLSCRPPMVKLVC 776
F SD +C C G + C P+ VL + C P
Sbjct: 554 DFPHPSDPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPGECCPQCPAPAGCPRPGAAHAR 613
Query: 777 PADNLRAEGLECTKT-CQNYDLECMSMGCVSGCLCPPGMVRHENRCVALERCP-CFHQGK 834
+ G C + C + + C + C PP H + C C +QGK
Sbjct: 614 HQEYFSPPGDPCRRCLCLDGSVSCQRLPC------PPAPCAHPRQGPCCPSCDGCLYQGK 667
Query: 835 EYAPGE---TVKIGCNTCVCRDRKWNCTDHVC 863
E+A GE + C+ C+C + +C C
Sbjct: 668 EFASGERFPSPTAACHLCLCWEGSVSCEPKAC 699
Score = 46.6 bits (109), Expect = 3e-04
Identities = 77/331 (23%), Positives = 107/331 (32%), Gaps = 72/331 (21%)
Query: 574 PRMTRFSEEACAVLTSPTFEACHRAVSPLPYLRNCRYDVCSCSDGR----------ECLC 623
P R+ +AC A + LP+ R C + + +G CL
Sbjct: 104 PEGARWEPDACTACVCQDGAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACTTCRCLT 163
Query: 624 GALASYAAACAGRGVRVAWREPGRCELNCP-----------KGQVYLQCGTPCNLTCRSL 672
GA+ +C+ + PG C CP GQ + G PC + CR L
Sbjct: 164 GAVQCQGPSCSELNCLESCTPPGEC---CPICCTEGGSHWEHGQEWTTPGDPCRI-CRCL 219
Query: 673 SYPDEECNEACLEGCFCPPGLYMDERGDCVPKAQCPCYYDG-EIFQPEDIFS-DHHTMCY 730
+ C C P G C P C+ +G E E + S D + C
Sbjct: 220 EGHIQCRQRECASLCPYPA---RPLPGTCCPVCD-GCFLNGREHRSGEPVGSGDPCSHCR 275
Query: 731 CEDGFMHCTMSGVPGSLLPDAVLSSPLSHRSKRSLSCRPPMVKLVCPADN---------- 780
C +G + C P P H K C P VC
Sbjct: 276 CANGSVQCEPLPCP---------PVPCRHPGKIPGQCCP-----VCDGCEYQGHQYQSQE 321
Query: 781 ---LRAEGLECTKTCQNYDLECMSMGC-VSGCLCPPGMVRHENRCVALERCP-CFHQGKE 835
L+ GL +CQ ++ C C V+ C P + CP C G+E
Sbjct: 322 TFRLQERGLCVRCSCQAGEVSCEEQECPVTPCALPAS---------GRQLCPACELDGEE 372
Query: 836 YAPG---ETVKIGCNTCVCRDRKWNCTDHVC 863
+A G E C CVC+D C +C
Sbjct: 373 FAEGVQWEPDGRPCTACVCQDGVPKCGAVLC 403
Score = 46.6 bits (109), Expect = 3e-04
Identities = 36/108 (33%), Positives = 46/108 (42%), Gaps = 19/108 (17%)
Query: 1159 HPEPLACPVQCVEGCHAHCPP-----GKILDELLQTCVDPEDCPVCEVAGRRFASGKKVT 1213
HP +C EG HAHC P L TC P DC C G+ + SG
Sbjct: 499 HPRDPCQECRCQEG-HAHCQPRPCPRAPCAHPLPGTCC-PNDCSGCAFGGKEYPSGADFP 556
Query: 1214 LNPSDPEHCQICHCDVVNLTCEA-------CQEPGGLVVPPTDAPVSP 1254
+PSDP C++C C N+ C A C EP +++P P P
Sbjct: 557 -HPSDP--CRLCRCLSGNVQCLARRCVPLPCPEP--VLLPGECCPQCP 599
Score = 44.3 bits (103), Expect = 0.002
Identities = 88/388 (22%), Positives = 121/388 (31%), Gaps = 111/388 (28%)
Query: 556 HGDCQDLQKQHSDPCALNPRMTRFSEEACAVLTSPTFEACHRAVSPL-PYLRNCRYDVCS 614
H Q+ DPC + +C L P H P P C Y
Sbjct: 611 HARHQEYFSPPGDPC--RRCLCLDGSVSCQRLPCPPAPCAHPRQGPCCPSCDGCLYQ--- 665
Query: 615 CSDGRECLCGA-LASYAAACAGRGVRVAWREPGRCELNCPKGQVYLQCGTP----CNLTC 669
G+E G S AAC + + W CE PK C P C C
Sbjct: 666 ---GKEFASGERFPSPTAACH---LCLCWEGSVSCE---PKACAPALCPFPARGDCCPDC 716
Query: 670 RSLSY-------------PDEECNEACLEGCFC--------PPGLY--MDERGDCVPKAQ 706
Y P E CN G F PPG + G C P Q
Sbjct: 717 DGCEYLGESYLSNQEFPDPREPCNLCTCLGGFVTCGRRPCEPPGCSHPLIPSGHCCPTCQ 776
Query: 707 CPCYYDGEIFQPEDIFSDHH----TMCYCEDGFMHCTMSGVPGSLLPD------------ 750
C Y G + D ++C C++G M C P +L P
Sbjct: 777 -GCRYHGVTTASGETLPDPLDPTCSLCTCQEGSMRCQKKPCPPALCPHPSPGPCFCPVCH 835
Query: 751 AVLSSPLSHRSKRSLS--------CR-----PPMVKLVCPADNLRAEGLE---CTKTCQN 794
+ LS H+ CR V+L CP + + E C C+
Sbjct: 836 SCLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCVRLQCPPLPCKLQVTERGSCCPRCRG 895
Query: 795 YDLECMSMG--------------CVSGCLCPPGMVRHEN-RCVAL---------ERCP-- 828
C++ G S C+C G+V +C++ + CP
Sbjct: 896 ----CLAHGEEHPEGSRWVPPDSACSSCVCHEGVVTCARIQCISSCAQPRQGPHDCCPQC 951
Query: 829 --CFHQGKEYAPGETVKIG---CNTCVC 851
C H+G++Y PGE+ + G C C+C
Sbjct: 952 SDCEHEGRKYEPGESFQPGADPCEVCIC 979
Score = 39.3 bits (90), Expect = 0.055
Identities = 40/149 (26%), Positives = 54/149 (36%), Gaps = 32/149 (21%)
Query: 253 TLCEC-AGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPA--------GMEYRQ 303
T C C G ++C P+ E C L T C P+C G E+
Sbjct: 157 TTCRCLTGAVQCQGPSCSEL--NC------LESCTPPGECCPICCTEGGSHWEHGQEWTT 208
Query: 304 CVSPCARTCQSLHINEMCQER-CVDGCSCPEGQLLDEGLCVESTECP----CVHSGKRYP 358
PC R C+ L + C++R C C P L G C CP C +G+ +
Sbjct: 209 PGDPC-RICRCLEGHIQCRQRECASLCPYPARPL--PGTC-----CPVCDGCFLNGREHR 260
Query: 359 PGTSLSRD--CNTCICRNSQWICSNEECP 385
G + C+ C C N C CP
Sbjct: 261 SGEPVGSGDPCSHCRCANGSVQCEPLPCP 289
Score = 37.7 bits (86), Expect = 0.16
Identities = 29/102 (28%), Positives = 37/102 (36%), Gaps = 20/102 (19%)
Query: 296 PAGMEYRQCVSPCARTCQSLHINEMCQERCVDGCSCPEGQLLDEGLCVESTECP----CV 351
P+G ++ PC R C+ L N C R CPE LL C +CP C
Sbjct: 550 PSGADFPHPSDPC-RLCRCLSGNVQCLARRCVPLPCPEPVLLPGECC---PQCPAPAGCP 605
Query: 352 HSGKRY--------PPGTSLSRDCNTCICRNSQWICSNEECP 385
G + PPG C C+C + C CP
Sbjct: 606 RPGAAHARHQEYFSPPGD----PCRRCLCLDGSVSCQRLPCP 643
Score = 37.4 bits (85), Expect = 0.21
Identities = 53/240 (22%), Positives = 76/240 (31%), Gaps = 76/240 (31%)
Query: 194 SSGEQWCERASPPSSSCNISSGEMQKGLWEQCQLLKSTSVFARCHPLVDPEP-----FVA 248
+SGE + P S C G M+ CQ C P + P P F
Sbjct: 786 ASGETLPDPLDPTCSLCTCQEGSMR------CQKKP-------CPPALCPHPSPGPCFCP 832
Query: 249 LCEKTL---------------------CEC-AGGLECA---CPALLEYARTCAQEGMVLY 283
+C L C C AG + C CP L C +
Sbjct: 833 VCHSCLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCVRLQCPPL-----PCKLQV---- 883
Query: 284 GWTDHSACSPVC----------PAGMEYRQCVSPCARTCQSLHINEMCQERCVDGCSCPE 333
T+ +C P C P G + S C+ + + +C+ C+ P
Sbjct: 884 --TERGSCCPRCRGCLAHGEEHPEGSRWVPPDSACSSCVCHEGVVTCARIQCISSCAQPR 941
Query: 334 GQLLDEGLCVESTECPCVHSGKRYPPGTSL---SRDCNTCICRNS-----QWICSNEECP 385
D C + ++C H G++Y PG S + C CIC C +CP
Sbjct: 942 QGPHD--CCPQCSDCE--HEGRKYEPGESFQPGADPCEVCICEPQPEGPPSLRCHRRQCP 997
Score = 36.2 bits (82), Expect = 0.47
Identities = 38/144 (26%), Positives = 48/144 (33%), Gaps = 32/144 (22%)
Query: 253 TLCECA-GGLECACPALLEYARTCAQEGMVLYGWTDHS--ACSPVCPAGMEYRQCVSPCA 309
T C C G C A L + R C+Q G S AC+ C QC P
Sbjct: 115 TACVCQDGAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACT-TCRCLTGAVQCQGP-- 171
Query: 310 RTCQSLHINEMCQERCVDGCSCPEGQLLDEGLCVESTECP--CVHSGKRYPPG---TSLS 364
+C L+ C++ C+ P G C CP C G + G T+
Sbjct: 172 -SCSELN--------CLESCTPP-------GEC-----CPICCTEGGSHWEHGQEWTTPG 210
Query: 365 RDCNTCICRNSQWICSNEECPGEC 388
C C C C EC C
Sbjct: 211 DPCRICRCLEGHIQCRQRECASLC 234
Score = 34.7 bits (78), Expect = 1.4
Identities = 36/149 (24%), Positives = 50/149 (33%), Gaps = 36/149 (24%)
Query: 255 CECAGG-LECA---CPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCAR 310
C CA G ++C CP + C G + C PVC G EY+
Sbjct: 274 CRCANGSVQCEPLPCPPV-----PCRHPGKI------PGQCCPVCD-GCEYQ------GH 315
Query: 311 TCQSLHINEMCQERCVDGCSCPEGQLLDEGLCVESTECPCVHSGKRYPPGTSLS------ 364
QS + + CSC G++ E T C SG++ P L
Sbjct: 316 QYQSQETFRLQERGLCVRCSCQAGEVSCEEQECPVTPCALPASGRQLCPACELDGEEFAE 375
Query: 365 --------RDCNTCICRNSQWICSNEECP 385
R C C+C++ C CP
Sbjct: 376 GVQWEPDGRPCTACVCQDGVPKCGAVLCP 404
Score = 33.9 bits (76), Expect = 2.3
Identities = 27/96 (28%), Positives = 32/96 (33%), Gaps = 23/96 (23%)
Query: 316 HINEMCQE-RCVDGCS------CPEGQLLDE--GLCVESTECPCVHSGKRYPPGTSL--- 363
H + CQE RC +G + CP G C + C GK YP G
Sbjct: 499 HPRDPCQECRCQEGHAHCQPRPCPRAPCAHPLPGTCCPNDCSGCAFGGKEYPSGADFPHP 558
Query: 364 SRDCNTCICRNSQWICSNEEC-----------PGEC 388
S C C C + C C PGEC
Sbjct: 559 SDPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPGEC 594
>gi|239755460 PREDICTED: similar to mucin, partial [Homo sapiens]
Length = 1064
Score = 206 bits (524), Expect = 3e-52
Identities = 185/717 (25%), Positives = 264/717 (36%), Gaps = 149/717 (20%)
Query: 1887 KRPGDVWTLPDQCHTVTCQPDGQTLLKSHRVNCDRGLRPSCPNSQSPVKVEETCGC--RW 1944
++ G+ W P+ C TC+ G ++ C R +P+C N VKV + GC +
Sbjct: 333 RKKGETWATPN-CSEATCE--GNNVISLRPRTCPRVEKPTCANGYPAVKVADQDGCCHHY 389
Query: 1945 TCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKEQ---DLEVILHNGACSPGARQGC 2001
C CVC+G H +TFDG + +C+YVL Q V++ N C C
Sbjct: 390 QCQCVCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVYGHFRVLVDNYFCGAEDGLSC 449
Query: 2002 MKSIEVKHSALSVEL-----HSDM--EVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNH 2054
+SI +++ V L H M E+ N ++VS + + V+ G M+
Sbjct: 450 PRSIILEYHQDRVVLTRKPVHGVMTNEIIFNNKVVSPGFRKNGIVVSRIGVKMYAT-IPE 508
Query: 2055 LGHIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEW 2114
LG F+ F +++ FA+ T G C
Sbjct: 509 LGVQVMFS--GLIFSVEVPFSKFANNTEGQCXXXXXXXTT-------------------- 546
Query: 2115 TVQRPGQTCQPILEEQCLVPDSSHCQVLLLPLFAECHKVLAPATFYAICQQDSCHQ---E 2171
P C P S CQ++L +F CH V+ P FY C D CH +
Sbjct: 547 ----PPAPCLP----------SPICQLILSKVFEPCHTVIPPLLFYEGCVFDRCHMTDLD 592
Query: 2172 QVCEVIASYAHLCRTNGVCVDWR--TPDFCAMSCPPSLVYNHCEHGCPRHCDGNVS-SCG 2228
VC + YA LC ++ +C+DWR T C +CP VY C P +C GN S S G
Sbjct: 593 VVCSSLELYAALCASHDICIDWRGRTGHMCPFTCPADKVYQPCGPSNPSYCYGNDSASLG 652
Query: 2229 DHP-----SEGCFCPPDKVMLEGS---CVPEEACTQCIGEDGVQHQFLEAWVPDHQPCQI 2280
P +EGCFCP + S CVP C +C+G P +P ++
Sbjct: 653 ALPEAGPITEGCFCPEGMTLFSTSAQVCVPT-GCPRCLG-------------PHGEPVKV 698
Query: 2281 CTCLSGRKVNCTTQPCPTAKAPTCGLCEVARLRQNADQCCPEYECVCDPVSCDLPPVPHC 2340
G V Q C CE A + C P C LPP C
Sbjct: 699 -----GHTVGMDCQECT---------CEAAT-----------WTLTCRPKLCPLPPA--C 731
Query: 2341 ERGLQPTLTNPGECRPNFTCACRKEECKRVSPPSCPPHRLPTLRKTQCCDEYECACNCVN 2400
P F V P+ P + QCC +Y CACN
Sbjct: 732 PL-------------PGF-----------VPVPAAP-------QAGQCCPQYSCACNTSR 760
Query: 2401 --STVSCPLGYLASTATNDCGCTTTTCLPDKVCVHRSTIYPVGQFWEEG-CDVCTCTDME 2457
V CP G A + C VC T+Y G C+ C C
Sbjct: 761 CPKPVGCPEGARAIPTYQEGACCPVQNCSWTVCSINGTLYQPGAVVSSSLCETCRCELPG 820
Query: 2458 DAVMGLRVAQCSQKPCEDSCRSGFTYVLHEGECCGRCLPSACEVVTGSPRGDSQSSWKSV 2517
V C + C C GF Y G+CCG C+ AC VT + + + +
Sbjct: 821 GPPSDAFVVSCETQICNTHCPVGFEYQEQSGQCCGTCVQVAC--VTNTSKSPAHLFYP-- 876
Query: 2518 GSQWASPENPCLINECVRVKEEVFIQQRNVSCPQLEVPVCPSGFQLSCKTSACCPSC 2574
G W+ N C+ ++C + ++ + + +CP P+ S + CC C
Sbjct: 877 GETWSDAGNHCVTHQCEKHQDGLVVVTTKKACP----PLSCSLDEARMSKDGCCRFC 929
Score = 138 bits (348), Expect = 7e-32
Identities = 89/279 (31%), Positives = 125/279 (44%), Gaps = 26/279 (9%)
Query: 2549 CPQLEVPV-CPSGFQL--SCKTSACCPSCRCERMEACMLNGTVIGPGKTVMIDVCTTCRC 2605
CP+ PV CP G + + + ACCP C C +NGT+ PG V +C TCRC
Sbjct: 761 CPK---PVGCPEGARAIPTYQEGACCPVQNCS-WTVCSINGTLYQPGAVVSSSLCETCRC 816
Query: 2606 MVQVGVIS-GFKLECRKTTCNP-CPLGYKEENNTGECCGRCLPTACTIQLRGGQIMTLKR 2663
+ G S F + C CN CP+G++ + +G+CCG C+ AC
Sbjct: 817 ELPGGPPSDAFVVSCETQICNTHCPVGFEYQEQSGQCCGTCVQVACVTNTSKSPAHLFYP 876
Query: 2664 DETLQDG---CDTHFCKVNERGEYFWEKRVTGCPPFDEHKCLAEGGKIMKIPGTCCDTCE 2720
ET D C TH C+ ++ G + CPP C + ++ K CC C
Sbjct: 877 GETWSDAGNHCVTHQCEKHQDGLVVVTTK-KACPPLS---CSLDEARMSK--DGCCRFCP 930
Query: 2721 EPEC---NDITARLQY----VKVGSCKSEVEVDIHYCQGKCA-SKAMYSIDINDVQDQCS 2772
P N T + + ++ C S V + YC+G C S +MYS++ N V+ +C
Sbjct: 931 PPPPPYQNQSTCAVYHRSLIIQQQGCSSSEPVRLAYCRGNCGDSSSMYSLEGNTVEHRCQ 990
Query: 2773 CCSPTRTEPMQVALHCTNGSVVYHEVLNAMECKCSPRKC 2811
CC RT V LHCT+GS EC C R+C
Sbjct: 991 CCQELRTSLRNVTLHCTDGSSRAFSYTEVEECGCMGRRC 1029
Score = 102 bits (253), Expect = 7e-21
Identities = 136/544 (25%), Positives = 204/544 (37%), Gaps = 107/544 (19%)
Query: 725 HHTMCYCEDGFMHCTMSGVPGSLLPDAVLSSPLSHRSKRSLSCRPPMVKLVCP-ADNLRA 783
++ +C + + S P + LP A +SP S+S P+ +L CP A R
Sbjct: 282 YYALCSQDCQVVRGVDSDCPSTTLPPAPATSP-------SISTSEPVTELGCPNAVPPRK 334
Query: 784 EGLECTKTCQNYDLECMSMGCVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAPGETVK 843
+G E T + C +S C +E+ C +
Sbjct: 335 KG-ETWATPNCSEATCEGNNVIS---------LRPRTCPRVEKPTCAN------------ 372
Query: 844 IGCNTCVCRDRKWNCTDHVCDATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPG 903
G D+ C + C CS G HY+TFDG Y F C YVLVQ G
Sbjct: 373 -GYPAVKVADQDGCCHHYQCQCVCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVY-G 430
Query: 904 TFRILVGNKGC-SHPSVKCKKRVTILVEGGEIELFDGEVNVKRPMKDETHFEVVESGRYI 962
FR+LV N C + + C + +I++E + D V ++P+ E++ + + +
Sbjct: 431 HFRVLVDNYFCGAEDGLSCPR--SIILEYHQ----DRVVLTRKPVHGVMTNEIIFNNKVV 484
Query: 963 ILLLGKALSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFG 1022
K VV I V + T E G+ F G+ VE F
Sbjct: 485 SPGFRKNGIVV----SRIGVKMYATIPE--LGVQVMFSGLI--------FSVEVPFSKFA 530
Query: 1023 NSWKVSSQCADTRKVPLDSSPATCHNNIMKQTMVDSSCRILTSDVFQDCNKLVDPEPYLD 1082
N+ QC + PA C + C+++ S VF+ C+ ++ P + +
Sbjct: 531 NN--TEGQCXXXXXXXT-TPPAPC--------LPSPICQLILSKVFEPCHTVIPPLLFYE 579
Query: 1083 VCIYDTCSCESIGDCACFCDTIAAYAHVCAQHGKVVTW--RTATLCPQSCEERNLRENGY 1140
C++D C + D C ++ YA +CA H + W RT +CP +C +
Sbjct: 580 GCVFDRC---HMTDLDVVCSSLELYAALCASHDICIDWRGRTGHMCPFTCPADKV----- 631
Query: 1141 ECEWRYNSCAPACQVTCQHPE-------PLACPVQCVEGCHAHCPPGKIL-DELLQTCVD 1192
Y C P+ C + P A P+ EGC CP G L Q CV
Sbjct: 632 -----YQPCGPSNPSYCYGNDSASLGALPEAGPI--TEGC--FCPEGMTLFSTSAQVCV- 681
Query: 1193 PEDCPVCEVAGRRFASGKKVTLNPSDPEHCQICHCDVV--NLTCE--------ACQEPGG 1242
P CP C G+ V + + CQ C C+ LTC AC PG
Sbjct: 682 PTGCPRC-----LGPHGEPVKVGHTVGMDCQECTCEAATWTLTCRPKLCPLPPACPLPGF 736
Query: 1243 LVVP 1246
+ VP
Sbjct: 737 VPVP 740
Score = 89.0 bits (219), Expect = 6e-17
Identities = 80/293 (27%), Positives = 109/293 (37%), Gaps = 58/293 (19%)
Query: 584 CAVLTSPTFEACHRAVSPLPYLRNCRYDVCSCSDGRECLCGALASYAAACAGRGVRVAWR 643
C ++ S FE CH + PL + C +D C +D + +C +L YAA CA + + WR
Sbjct: 557 CQLILSKVFEPCHTVIPPLLFYEGCVFDRCHMTD-LDVVCSSLELYAALCASHDICIDWR 615
Query: 644 EPGR----CELNCPKGQVYLQCGTPCNLTCRSLSYPDEECNEACL-------EGCFCPPG 692
GR C CP +VY CG P N S Y ++ + L EGCFCP G
Sbjct: 616 --GRTGHMCPFTCPADKVYQPCG-PSN---PSYCYGNDSASLGALPEAGPITEGCFCPEG 669
Query: 693 --LYMDERGDCVPKAQCPCYYDGEIFQPEDIFSDHHTMCYCEDGFMHCTMSGVPGSLLPD 750
L+ CVP C G +P + H C++ CT
Sbjct: 670 MTLFSTSAQVCVPTGCPRCL--GPHGEPVKV--GHTVGMDCQE----CTCEA-------- 713
Query: 751 AVLSSPLSHRSKRSLSCRPPMVKL--VCPADNL--RAEGLECTKTCQNYDLECMSMGCVS 806
+ +L+CRP + L CP + + C Y C + C
Sbjct: 714 ----------ATWTLTCRPKLCPLPPACPLPGFVPVPAAPQAGQCCPQYSCACNTSRCPK 763
Query: 807 GCLCPPGM----VRHENRCVALERCP---CFHQGKEYAPGETVKIG-CNTCVC 851
CP G E C ++ C C G Y PG V C TC C
Sbjct: 764 PVGCPEGARAIPTYQEGACCPVQNCSWTVCSINGTLYQPGAVVSSSLCETCRC 816
Score = 60.8 bits (146), Expect = 2e-08
Identities = 53/174 (30%), Positives = 73/174 (41%), Gaps = 17/174 (9%)
Query: 225 CQLLKSTSVFARCHPLVDPEPFVALCEKTLCECAGGLECACPALLEYARTCAQEGMVL-- 282
CQL+ S VF CH ++ P F C C L+ C +L YA CA + +
Sbjct: 557 CQLILS-KVFEPCHTVIPPLLFYEGCVFDRCHMTD-LDVVCSSLELYAALCASHDICIDW 614
Query: 283 YGWTDHSACSPVCPAGMEYRQCVSPCARTC---QSLHINEMCQERCV-DGCSCPEGQLL- 337
G T H C CPA Y+ C C S + + + + +GC CPEG L
Sbjct: 615 RGRTGHM-CPFTCPADKVYQPCGPSNPSYCYGNDSASLGALPEAGPITEGCFCPEGMTLF 673
Query: 338 --DEGLCVESTECP-CVHS-GKRYPPGTSLSRDCNTCICRNSQW--ICSNEECP 385
+CV T CP C+ G+ G ++ DC C C + W C + CP
Sbjct: 674 STSAQVCVP-TGCPRCLGPHGEPVKVGHTVGMDCQECTCEAATWTLTCRPKLCP 726
Score = 38.5 bits (88), Expect = 0.095
Identities = 18/68 (26%), Positives = 31/68 (45%), Gaps = 2/68 (2%)
Query: 379 CSNEECPGECLVTGQSHFKSFDNRYFTFSGICQYLLARDCQD--HSFSIVIETVQCADDR 436
C + +C C G H+ +FD Y+TF C Y+L + F ++++ C +
Sbjct: 386 CHHYQCQCVCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVYGHFRVLVDNYFCGAED 445
Query: 437 DAVCTRSV 444
C RS+
Sbjct: 446 GLSCPRSI 453
Score = 34.3 bits (77), Expect = 1.8
Identities = 32/125 (25%), Positives = 44/125 (35%), Gaps = 22/125 (17%)
Query: 2279 QICTCLSGRKVNC--TTQPCPTAKAPTCGLCEVARLRQNADQCCPEYECVCDPVSCDLPP 2336
Q C + G +C TT P A +P+ E P E C +PP
Sbjct: 288 QDCQVVRGVDSDCPSTTLPPAPATSPSISTSE------------PVTELGCPNA---VPP 332
Query: 2337 VPHCERGLQPTLTNPGECRPNFTCACRKEECKRVSPPSCPPHRLPTLRKTQ---CCDEYE 2393
E P + C N + R C RV P+C + P ++ CC Y+
Sbjct: 333 RKKGETWATPNCSE-ATCEGNNVISLRPRTCPRVEKPTCA-NGYPAVKVADQDGCCHHYQ 390
Query: 2394 CACNC 2398
C C C
Sbjct: 391 CQCVC 395
>gi|239757284 PREDICTED: similar to Fc fragment of IgG binding protein
[Homo sapiens]
Length = 593
Score = 192 bits (489), Expect = 3e-48
Identities = 161/590 (27%), Positives = 234/590 (39%), Gaps = 90/590 (15%)
Query: 475 LLKGDLRI-QHTVTASVRLSYGEDLQMDWDGRGRLLVKLSPVYAGKTCGLCGNYNGNQGD 533
L G +R QH + +G L++ +D + V + Y + CGLCGNYNG+ D
Sbjct: 7 LANGQIRASQHGSDVVIETDFG--LRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKD 64
Query: 534 DFLTPSGLAEPRVEDFGNAWK-------------LHGDCQDLQKQHSDPCALNPRMTRFS 580
DF P+G +FGN+W+ +D H P L + +
Sbjct: 65 DFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQK-- 122
Query: 581 EEACAVLTSPT--FEACHRAVSPLPYLRNCRYDVCSCSDGRECLCGALASYAAACAGRGV 638
EE C +L+SPT +CH+ V P L++C +D+C LC + +Y +AC G
Sbjct: 123 EEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGG 182
Query: 639 RV-AWREPGRCELNCPKGQVYLQCGTPCNLTCRSLSYPDEECNEACLEGCFCPPGLYMDE 697
V WR C + CP Y C C+L C +LS P +C + C EGC C G +
Sbjct: 183 HVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAP-PQCQDGCAEGCQCDSGFLYNG 241
Query: 698 RGDCVPKAQCPCYYDGEIFQPED--IFSDHHTMCYCEDGFMHCTMSGVPGSLLPDAVLSS 755
+ CVP QC CY++G ++PE + + C C G +
Sbjct: 242 QA-CVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQ--------------- 285
Query: 756 PLSHRSKRSLSCRPPMVKLVCPAD----NLRAEGLECTKTCQNYDLECMSMGCVSGCLCP 811
H K C+P L C +L G++ Y+ + + + L P
Sbjct: 286 --EHSCKPGQVCQPSGGILSCVTKVTLRSLAQTGVDVEGAAILYNGQPLKV------LLP 337
Query: 812 PGMVRHENRCVALERCPCFHQGKEYAPGETVKIGCNTCVCRDRKWNCTDHVCDATCSTIG 871
L PC G P ET K VC +ATC G
Sbjct: 338 -----------LLSPDPC--HGVTCRPQETCKEQGGQGVCLPN--------YEATCWLWG 376
Query: 872 MAHYLTFDGLKYLFPGECQYVLVQDYC------GSNPGTFRILVGNKGCSHPSVKCKKRV 925
HY +FDG K+ F G C YVL C G P F + N+ +P+V + V
Sbjct: 377 DPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTP--FTVTTKNQNRGNPAVSYVRVV 434
Query: 926 TILVEGGEIELFDGEVNVKR--------PMK-DETHFEVVESGRYIILLLGKALSVVWDR 976
T+ G I + E+ R P+ + V + +L+ L V +D
Sbjct: 435 TVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDW 494
Query: 977 HLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWK 1026
+ + V L +Y VCGLCGN D NND N + +G SW+
Sbjct: 495 NWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWR 544
Score = 131 bits (329), Expect = 1e-29
Identities = 139/513 (27%), Positives = 192/513 (37%), Gaps = 107/513 (20%)
Query: 147 QVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGEQWC--ERAS 204
+V + Y+ + CGLCGN+N +DDF G+ + +F NSW + C
Sbjct: 40 RVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPC 99
Query: 205 PPSSSCNISSG----EMQKGLWEQ--CQLLKS-TSVFARCHPLVDPEPFVALCEKTLCEC 257
PP S I S E++K ++ C LL S T + CH LVDP+ + C LC
Sbjct: 100 PPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLG 159
Query: 258 AGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYR--------------- 302
G L C + Y C G + W + C CP Y
Sbjct: 160 GGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSA 219
Query: 303 --QCVSPCARTCQS----LHINEMCQ----------------------ERCVDGCSCPEG 334
QC CA CQ L+ + C + C C+C G
Sbjct: 220 PPQCQDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAG 279
Query: 335 QLLDEGLCVESTECP---CVHSGKRYPPGTS----------------------------- 362
+++ +C E + P C SG T
Sbjct: 280 KVV---VCQEHSCKPGQVCQPSGGILSCVTKVTLRSLAQTGVDVEGAAILYNGQPLKVLL 336
Query: 363 --LSRD-CNTCICRNSQWICSNEECPGECL--------VTGQSHFKSFDNRYFTFSGICQ 411
LS D C+ CR Q C + G CL + G H+ SFD R F F G C
Sbjct: 337 PLLSPDPCHGVTCR-PQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCN 395
Query: 412 YLLARD-CQDHSFS----IVIETVQCADDRDAVC-TRSVTVRLPGLHNSLVKLKHGAGVA 465
Y+LA C S + T AV R VTV G + S+ K + G V
Sbjct: 396 YVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGK-VR 454
Query: 466 MDGQDVQLPLLKGDLRIQHTVTASVRLSYGE-DLQMDWDGRGRLLVKLSPVYAGKTCGLC 524
++G LP+ D RI T AS L + LQ+ +D R+ V L Y G CGLC
Sbjct: 455 VNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLC 514
Query: 525 GNYNGNQGDDFLTPSGLAEPRVEDFGNAWKLHG 557
GN + N +D + P+G P + +G +W+ G
Sbjct: 515 GNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPG 547
Score = 107 bits (268), Expect = 1e-22
Identities = 83/300 (27%), Positives = 123/300 (41%), Gaps = 28/300 (9%)
Query: 957 ESGRYIILLLGKALSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEE 1016
+ G +++ L V +D + V + Y +++CGLCGN++G +D N
Sbjct: 16 QHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAG 75
Query: 1017 DPVDFGNSWK---VSSQCADTRKVPLDSSPA----TCHNNIMKQTMVDSSCRILTSDV-- 1067
+ +FGNSW+ S C P S C + K+ + C +L+S
Sbjct: 76 NANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGP 135
Query: 1068 FQDCNKLVDPEPYLDVCIYDTCSCESIGDCACFCDTIAAYAHVC-AQHGKVVTWRTATLC 1126
C+KLVDP+ L CI+D C G+ + C I AY C A G V WRT T C
Sbjct: 136 LSSCHKLVDPQGPLKDCIFDLCL--GGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFC 193
Query: 1127 PQSCEERNLRENGYECEWRYNSCAPACQVTCQHPEPLACPVQCVEGCHAHCPPGKILDEL 1186
P C + Y CA C + C L+ P QC +GC C
Sbjct: 194 PMECPPNS----------HYELCADTCSLGC---SALSAPPQCQDGCAEGCQCDSGFLYN 240
Query: 1187 LQTCVDPEDCPVCEVAGRRFASGKKVTLNPSDPEHCQICHCDVVNLTCEACQEPGGLVVP 1246
Q CV + C C G + + V ++ + + C CH V + E +PG + P
Sbjct: 241 GQACVPIQQCG-CYHNGVYYEPEQTVLID-NCRQQC-TCHAGKVVVCQEHSCKPGQVCQP 297
Score = 76.3 bits (186), Expect = 4e-13
Identities = 66/250 (26%), Positives = 98/250 (39%), Gaps = 31/250 (12%)
Query: 2074 PKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTVQRPGQTCQPIL-----E 2128
P + + GLCG + + +DF +G+ + W P C P
Sbjct: 44 PGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGS 103
Query: 2129 EQCL------------VPDSSHCQVLLLPL--FAECHKVLAPATFYAICQQDSC----HQ 2170
E C+ C +L P + CHK++ P C D C +
Sbjct: 104 EDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNL 163
Query: 2171 EQVCEVIASYAHLCRTNGVCVD-WRTPDFCAMSCPPSLVYNHCEHGCPRHCDGNVS--SC 2227
+C I +Y C+ G V+ WRT FC M CPP+ Y C C C + C
Sbjct: 164 SILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQC 223
Query: 2228 GDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWVPDHQPC-QICTCLSG 2286
D +EGC C + +CVP + C C +GV ++ + + D+ C Q CTC +G
Sbjct: 224 QDGCAEGCQCDSGFLYNGQACVPIQQC-GCY-HNGVYYEPEQTVLIDN--CRQQCTCHAG 279
Query: 2287 RKVNCTTQPC 2296
+ V C C
Sbjct: 280 KVVVCQEHSC 289
Score = 54.7 bits (130), Expect = 1e-06
Identities = 48/183 (26%), Positives = 70/183 (38%), Gaps = 15/183 (8%)
Query: 33 ARCSLFGSDFVNTFDGSMYSFAGYCSYLLAG-GCQKRS------FSIIGDFQNGKRVSLS 85
A C L+G ++FDG + F G C+Y+LA GC S F++ QN ++S
Sbjct: 370 ATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVS 429
Query: 86 VY-------LGEFFDIHLFVNGTVTQGDQRVSMPYA-SKGLYLETEAGYYKLSGEAYGFV 137
LG IH G V ++P + + G T+ L +G
Sbjct: 430 YVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQ 489
Query: 138 ARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGE 197
D + V L Y CGLCGN + +D + GTL + SW +
Sbjct: 490 VSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWD 549
Query: 198 QWC 200
C
Sbjct: 550 PLC 552
Score = 43.9 bits (102), Expect = 0.002
Identities = 60/246 (24%), Positives = 94/246 (38%), Gaps = 40/246 (16%)
Query: 1896 PDQCHTVTCQPDGQTLLKSHRVNCDRGLRPSC-PNSQSPVKVEETCGCRWTCPCVCTGSS 1954
PD CH VTC+P Q K ++G + C PN E TC W P
Sbjct: 341 PDPCHGVTCRP--QETCK------EQGGQGVCLPN------YEATCWL-WGDP------- 378
Query: 1955 TRHIVTFDGQNFKLTGSCSYVLFQN-----KEQDLE--VILHNGACSPGARQGCMKSIEV 2007
H +FDG+ F G+C+YVL Q L + ++ + V
Sbjct: 379 --HYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTV 436
Query: 2008 KHSALSVELHSDM--EVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHLGHIFTFTPQN 2065
++ +H D +V VNG L ++P + ++V + G ++ N
Sbjct: 437 AALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSY-DWN 495
Query: 2066 NEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTVQRPGQTCQP 2125
+ L P ++ GLCG D N ND + +GT+ W + PG P
Sbjct: 496 WRVDVTL-PSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSW--RAPG--WDP 550
Query: 2126 ILEEQC 2131
+ ++C
Sbjct: 551 LCWDEC 556
Score = 32.7 bits (73), Expect = 5.2
Identities = 23/71 (32%), Positives = 33/71 (46%), Gaps = 13/71 (18%)
Query: 2557 CPSGFQLSCKTSACCPSCRCERMEACMLNGTVIGPGKTVMIDVC-TTCRCMVQVGVISGF 2615
C SGF + + AC P +C C NG P +TV+ID C C C +G
Sbjct: 233 CDSGFLYNGQ--ACVPIQQC----GCYHNGVYYEPEQTVLIDNCRQQCTCH------AGK 280
Query: 2616 KLECRKTTCNP 2626
+ C++ +C P
Sbjct: 281 VVVCQEHSCKP 291
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.137 0.448
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 127,864,618
Number of Sequences: 37866
Number of extensions: 6746597
Number of successful extensions: 21059
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 95
Number of HSP's successfully gapped in prelim test: 247
Number of HSP's that attempted gapping in prelim test: 14868
Number of HSP's gapped (non-prelim): 3530
length of query: 2813
length of database: 18,247,518
effective HSP length: 120
effective length of query: 2693
effective length of database: 13,703,598
effective search space: 36903789414
effective search space used: 36903789414
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 71 (32.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.