BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|89037350 PREDICTED: hypothetical protein [Homo sapiens] (414 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|169207312 PREDICTED: hypothetical protein [Homo sapiens] 860 0.0 gi|239750650 PREDICTED: hypothetical protein [Homo sapiens] 860 0.0 gi|89037350 PREDICTED: hypothetical protein [Homo sapiens] 860 0.0 gi|163965366 nascent polypeptide-associated complex alpha subuni... 87 4e-17 gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 76 5e-14 gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 76 5e-14 gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens] 65 1e-10 gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens] 65 1e-10 gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 64 2e-10 gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 64 3e-10 gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 62 7e-10 gi|158854042 hypothetical protein LOC222183 [Homo sapiens] 61 2e-09 gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap... 61 2e-09 gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 60 3e-09 gi|169160903 PREDICTED: hypothetical protein [Homo sapiens] 60 3e-09 gi|48375167 microtubule-associated protein 6 isoform 2 [Homo sap... 60 4e-09 gi|48375173 microtubule-associated protein 6 isoform 1 [Homo sap... 60 4e-09 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 60 5e-09 gi|110832843 TBP-associated factor 4 [Homo sapiens] 60 5e-09 gi|160707881 formin 2 [Homo sapiens] 59 6e-09 gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 57 2e-08 gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 57 2e-08 gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 57 2e-08 gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H... 57 2e-08 gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens] 57 2e-08 gi|47132519 Ras association and pleckstrin homology domains 1 is... 57 3e-08 gi|153281158 dual specificity phosphatase 8 [Homo sapiens] 57 3e-08 gi|182507165 thymus expressed gene 3-like [Homo sapiens] 57 4e-08 gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Ho... 57 4e-08 gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 57 4e-08 >gi|169207312 PREDICTED: hypothetical protein [Homo sapiens] Length = 414 Score = 860 bits (2222), Expect = 0.0 Identities = 414/414 (100%), Positives = 414/414 (100%) Query: 1 MSELESGEIRSEEGRPTTESRIRPRLAEALSQPTLRHSASALRPPRLSRGKDLKPRCGRG 60 MSELESGEIRSEEGRPTTESRIRPRLAEALSQPTLRHSASALRPPRLSRGKDLKPRCGRG Sbjct: 1 MSELESGEIRSEEGRPTTESRIRPRLAEALSQPTLRHSASALRPPRLSRGKDLKPRCGRG 60 Query: 61 PAHSPDPGEGCEAWRRLSADRWPRPASLSPRAALASAPGQKPQPARQAQLPRPVSGVRPP 120 PAHSPDPGEGCEAWRRLSADRWPRPASLSPRAALASAPGQKPQPARQAQLPRPVSGVRPP Sbjct: 61 PAHSPDPGEGCEAWRRLSADRWPRPASLSPRAALASAPGQKPQPARQAQLPRPVSGVRPP 120 Query: 121 PRGRVGLSQAPGRPLGACARAKGIRLVNPSPPRPPEPIPASAAVTSGLTARGPNTSATPG 180 PRGRVGLSQAPGRPLGACARAKGIRLVNPSPPRPPEPIPASAAVTSGLTARGPNTSATPG Sbjct: 121 PRGRVGLSQAPGRPLGACARAKGIRLVNPSPPRPPEPIPASAAVTSGLTARGPNTSATPG 180 Query: 181 PQKGRGSAERTNHIPKDKQRVAAPPPPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRT 240 PQKGRGSAERTNHIPKDKQRVAAPPPPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRT Sbjct: 181 PQKGRGSAERTNHIPKDKQRVAAPPPPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRT 240 Query: 241 RPLPRTSSFLSEVPSTRPLCATSSSHSAPLPFFWSPLRNPSPRPAPACGELRLGRLSPPR 300 RPLPRTSSFLSEVPSTRPLCATSSSHSAPLPFFWSPLRNPSPRPAPACGELRLGRLSPPR Sbjct: 241 RPLPRTSSFLSEVPSTRPLCATSSSHSAPLPFFWSPLRNPSPRPAPACGELRLGRLSPPR 300 Query: 301 ADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAESRRGPGPAQGPPSRRDE 360 ADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAESRRGPGPAQGPPSRRDE Sbjct: 301 ADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAESRRGPGPAQGPPSRRDE 360 Query: 361 PRRVVIAARECGREGSELPPSGEETPGRRKSPSQSCKKGGESILHSVVCLVGDF 414 PRRVVIAARECGREGSELPPSGEETPGRRKSPSQSCKKGGESILHSVVCLVGDF Sbjct: 361 PRRVVIAARECGREGSELPPSGEETPGRRKSPSQSCKKGGESILHSVVCLVGDF 414 >gi|239750650 PREDICTED: hypothetical protein [Homo sapiens] Length = 414 Score = 860 bits (2222), Expect = 0.0 Identities = 414/414 (100%), Positives = 414/414 (100%) Query: 1 MSELESGEIRSEEGRPTTESRIRPRLAEALSQPTLRHSASALRPPRLSRGKDLKPRCGRG 60 MSELESGEIRSEEGRPTTESRIRPRLAEALSQPTLRHSASALRPPRLSRGKDLKPRCGRG Sbjct: 1 MSELESGEIRSEEGRPTTESRIRPRLAEALSQPTLRHSASALRPPRLSRGKDLKPRCGRG 60 Query: 61 PAHSPDPGEGCEAWRRLSADRWPRPASLSPRAALASAPGQKPQPARQAQLPRPVSGVRPP 120 PAHSPDPGEGCEAWRRLSADRWPRPASLSPRAALASAPGQKPQPARQAQLPRPVSGVRPP Sbjct: 61 PAHSPDPGEGCEAWRRLSADRWPRPASLSPRAALASAPGQKPQPARQAQLPRPVSGVRPP 120 Query: 121 PRGRVGLSQAPGRPLGACARAKGIRLVNPSPPRPPEPIPASAAVTSGLTARGPNTSATPG 180 PRGRVGLSQAPGRPLGACARAKGIRLVNPSPPRPPEPIPASAAVTSGLTARGPNTSATPG Sbjct: 121 PRGRVGLSQAPGRPLGACARAKGIRLVNPSPPRPPEPIPASAAVTSGLTARGPNTSATPG 180 Query: 181 PQKGRGSAERTNHIPKDKQRVAAPPPPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRT 240 PQKGRGSAERTNHIPKDKQRVAAPPPPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRT Sbjct: 181 PQKGRGSAERTNHIPKDKQRVAAPPPPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRT 240 Query: 241 RPLPRTSSFLSEVPSTRPLCATSSSHSAPLPFFWSPLRNPSPRPAPACGELRLGRLSPPR 300 RPLPRTSSFLSEVPSTRPLCATSSSHSAPLPFFWSPLRNPSPRPAPACGELRLGRLSPPR Sbjct: 241 RPLPRTSSFLSEVPSTRPLCATSSSHSAPLPFFWSPLRNPSPRPAPACGELRLGRLSPPR 300 Query: 301 ADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAESRRGPGPAQGPPSRRDE 360 ADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAESRRGPGPAQGPPSRRDE Sbjct: 301 ADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAESRRGPGPAQGPPSRRDE 360 Query: 361 PRRVVIAARECGREGSELPPSGEETPGRRKSPSQSCKKGGESILHSVVCLVGDF 414 PRRVVIAARECGREGSELPPSGEETPGRRKSPSQSCKKGGESILHSVVCLVGDF Sbjct: 361 PRRVVIAARECGREGSELPPSGEETPGRRKSPSQSCKKGGESILHSVVCLVGDF 414 >gi|89037350 PREDICTED: hypothetical protein [Homo sapiens] Length = 414 Score = 860 bits (2222), Expect = 0.0 Identities = 414/414 (100%), Positives = 414/414 (100%) Query: 1 MSELESGEIRSEEGRPTTESRIRPRLAEALSQPTLRHSASALRPPRLSRGKDLKPRCGRG 60 MSELESGEIRSEEGRPTTESRIRPRLAEALSQPTLRHSASALRPPRLSRGKDLKPRCGRG Sbjct: 1 MSELESGEIRSEEGRPTTESRIRPRLAEALSQPTLRHSASALRPPRLSRGKDLKPRCGRG 60 Query: 61 PAHSPDPGEGCEAWRRLSADRWPRPASLSPRAALASAPGQKPQPARQAQLPRPVSGVRPP 120 PAHSPDPGEGCEAWRRLSADRWPRPASLSPRAALASAPGQKPQPARQAQLPRPVSGVRPP Sbjct: 61 PAHSPDPGEGCEAWRRLSADRWPRPASLSPRAALASAPGQKPQPARQAQLPRPVSGVRPP 120 Query: 121 PRGRVGLSQAPGRPLGACARAKGIRLVNPSPPRPPEPIPASAAVTSGLTARGPNTSATPG 180 PRGRVGLSQAPGRPLGACARAKGIRLVNPSPPRPPEPIPASAAVTSGLTARGPNTSATPG Sbjct: 121 PRGRVGLSQAPGRPLGACARAKGIRLVNPSPPRPPEPIPASAAVTSGLTARGPNTSATPG 180 Query: 181 PQKGRGSAERTNHIPKDKQRVAAPPPPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRT 240 PQKGRGSAERTNHIPKDKQRVAAPPPPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRT Sbjct: 181 PQKGRGSAERTNHIPKDKQRVAAPPPPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRT 240 Query: 241 RPLPRTSSFLSEVPSTRPLCATSSSHSAPLPFFWSPLRNPSPRPAPACGELRLGRLSPPR 300 RPLPRTSSFLSEVPSTRPLCATSSSHSAPLPFFWSPLRNPSPRPAPACGELRLGRLSPPR Sbjct: 241 RPLPRTSSFLSEVPSTRPLCATSSSHSAPLPFFWSPLRNPSPRPAPACGELRLGRLSPPR 300 Query: 301 ADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAESRRGPGPAQGPPSRRDE 360 ADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAESRRGPGPAQGPPSRRDE Sbjct: 301 ADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAESRRGPGPAQGPPSRRDE 360 Query: 361 PRRVVIAARECGREGSELPPSGEETPGRRKSPSQSCKKGGESILHSVVCLVGDF 414 PRRVVIAARECGREGSELPPSGEETPGRRKSPSQSCKKGGESILHSVVCLVGDF Sbjct: 361 PRRVVIAARECGREGSELPPSGEETPGRRKSPSQSCKKGGESILHSVVCLVGDF 414 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 86.7 bits (213), Expect = 4e-17 Identities = 117/430 (27%), Positives = 153/430 (35%), Gaps = 70/430 (16%) Query: 13 EGRPTTESRIRPRLAEALSQPTLRHSAS--ALRPPRLSRGKDLKPRCGRGP----AHSPD 66 +G PTT + P + P+L+ + + A PP +G P P A P Sbjct: 1054 KGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPS-PKGGPATPSPKGAPMPPAATPPS 1112 Query: 67 PGEGCEAWRRLSADRWPRPASLSPRAALASAPGQKPQPARQAQLPRPVSGVR-PPPRGRV 125 P G A P SP+ LA+ P + A P P G+ PPP+G Sbjct: 1113 PKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKG-- 1170 Query: 126 GLSQAPGRPLGACARAKGIRLVNPSP------PRPPEPIPASAAVTSGLTARGPNTSATP 179 AP P KG L PSP P P P T +ATP Sbjct: 1171 ----APTTPAATPPSPKG-GLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP 1225 Query: 180 GPQKGRGSAERTNHIPKDKQRVAAPPPPER-PRVPFCRGSSGLSVPTPPEHAGGRRKKFT 238 KG + P A PP P+ P P +G+ TPP GG Sbjct: 1226 PSPKGGLATPSPKGAPTTP--AATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPH 1283 Query: 239 RTRPLPRTSSFLSEVPSTRPLCATSSSHSAPLPFFWSPLRNPSPRPAPACGELRLGRLSP 298 + P P + PS + ATS AP P +P PSP+ +P + G +P Sbjct: 1284 KGAPNPAVVT----PPSPKGGPATSPPKGAPTPPAATP---PSPKGSPGTPPPK-GAPTP 1335 Query: 299 PRAD------------TGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAESRR 346 P T SS GG + P SK P PPA T G P Sbjct: 1336 PAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEG--PTPPAATPSHKGGPAMTP------- 1386 Query: 347 GPGPAQGP--PSRRDEPRRVVIA--------ARECGREGSELPPSGEETP------GRRK 390 P P +GP PS + +P + A REG+ P G+ TP +K Sbjct: 1387 -PSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKK 1445 Query: 391 SPSQSCKKGG 400 +P+ S KGG Sbjct: 1446 APATSAPKGG 1455 Score = 75.1 bits (183), Expect = 1e-13 Identities = 104/369 (28%), Positives = 124/369 (33%), Gaps = 74/369 (20%) Query: 61 PAHSPDPGEGCEAWRRLSADRWPRPASLSPRAALASAPGQKPQPARQAQLPRPVSGVRPP 120 PA +P +G A A +P+ AS P A S G P + P Sbjct: 1012 PAVTPPSPKGSPA-----ATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPS 1066 Query: 121 PRG---RVGLSQAPGRPLGACARAKGIRLVNPSP---PRPPEPIPAS------------A 162 P+G L AP P KG PSP P PP P S A Sbjct: 1067 PKGGPATPSLKGAPTPPAATPPSPKG-GPATPSPKGAPMPPAATPPSPKGGLATPPHKGA 1125 Query: 163 AVTSGLTARGPNTSATPGPQKGRGSAERTNHIPKDKQRVAAPPPPERPRVPFCRGSS--- 219 T T P P KG + P K +A PPP P P S Sbjct: 1126 PTTPAATPPSPKGGLATPPPKGAPTTPAATP-PSPKGGLATPPPKGAPTTPAATPPSPKG 1184 Query: 220 GLSVP-----------TPPEHAGGRRKKFTRTRPLPRTSSFLSEVPSTRPLCATSSSHSA 268 GL+ P TPP GG + P ++ PS + AT S A Sbjct: 1185 GLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAAT----PPSPKGGLATPSPKGA 1240 Query: 269 PLPFFWSPLRNPSPRPAPACGELRLGRLSPPRADTGGSSSGGCSGPDSKHRTLPA---PP 325 P +P PSP+ PA + G +PP A T S GG + P K PA PP Sbjct: 1241 PTTPAATP---PSPKGGPATPPPK-GAPTPPAA-TPPSLKGGLATPPHKGAPNPAVVTPP 1295 Query: 326 APTAWPAAGAP-GAPNPAESRRGPGPAQGPPSRRDEPRRVVIAARECGREGSELPPSGEE 384 +P PA P GAP P PA PPS + P PP G Sbjct: 1296 SPKGGPATSPPKGAPTP--------PAATPPSPKGSP--------------GTPPPKGAP 1333 Query: 385 TPGRRKSPS 393 TP PS Sbjct: 1334 TPPAVTPPS 1342 Score = 67.4 bits (163), Expect = 2e-11 Identities = 75/275 (27%), Positives = 98/275 (35%), Gaps = 19/275 (6%) Query: 85 PASLSPRAALA-SAPGQKPQPARQAQLPRPVSGVRPPPRGRVGLSQAPGRPLGACARAKG 143 PA+ +P+ A A S P+ AR P+ + P + P P G A Sbjct: 900 PATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSP 959 Query: 144 IRLVNPSPPRPPEPIPASAAVTSGLTARGPNTSATPGPQKGRGSAERTNHIPKDKQRVAA 203 P+PP P P T +ATP KG + P Sbjct: 960 KWA--PTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPP 1017 Query: 204 PPPPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRTRPLPR--TSSFLSEVPSTRPLCA 261 P PF +G+S TPP G PLP+ ++ + +PS + A Sbjct: 1018 SPKGSPAATPFPKGASTPPAATPPSPKGS-----PAATPLPKGAPTTPAATLPSPKGGPA 1072 Query: 262 TSSSHSAPLPFFWSPLRNPSPRPAPACGELRLGRLSPPRADTGGSSSGGCSGPDSKHRTL 321 T S AP P +P PSP+ PA + G PP A T S GG + P K Sbjct: 1073 TPSLKGAPTPPAATP---PSPKGGPATPSPK-GAPMPPAA-TPPSPKGGLATPPHK---- 1123 Query: 322 PAPPAPTAWPAAGAPGAPNPAESRRGPGPAQGPPS 356 AP P A P + G P PA PPS Sbjct: 1124 GAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPS 1158 Score = 55.1 bits (131), Expect = 1e-07 Identities = 98/452 (21%), Positives = 146/452 (32%), Gaps = 84/452 (18%) Query: 11 SEEGRPTTESRI--RPRLAEALSQPTLRHSASALRPPRLSRGKDLKPRCGRGPAHSPDPG 68 S +G PTT + P+ A P + A PP L G P G +P+P Sbjct: 1236 SPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKG-----APNPA 1290 Query: 69 EGCEAWRRLSADRWPRPASLSPRAALASAPGQKPQPARQAQLPRPVSGVRPPPRGRVGL- 127 + P + +P AA +P P P P + P P+G L Sbjct: 1291 VVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLP 1350 Query: 128 ---------------SQAPGRPLGACARAKGIRLVNPSPPRPPE-PIPASAAVTSGLTAR 171 + P P + G + PSP R P P P + + Sbjct: 1351 ATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPL 1410 Query: 172 GPNTS-ATPGPQKGRGSAERTNHIPKD------KQRVAAPPPPERPRVPFCRGSSGLSVP 224 P + ATP ++G + + + P K+ A P P P +G L Sbjct: 1411 SPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAV 1470 Query: 225 TPPEHAGGRRKKFTRTRPLPRTS-----------------SFLSEVPST-----RPLCAT 262 TPP K T P+ + S EVP+T P+ T Sbjct: 1471 TPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPT 1530 Query: 263 SSSHSAPLPFFWSP--------LRNPSPRPAPACGELRLGRLSP-------PRADTGGSS 307 ++ S P +P + PSP+ PA + +P P A T + Sbjct: 1531 ATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTY 1590 Query: 308 SGGCSGPDSKHRTLP----------APPAPTAWPAAGAPGAPNPAESRRGPGPAQGPPSR 357 G P K +P AP P P + G PA P P S Sbjct: 1591 KG---APSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSL 1647 Query: 358 RDEPRRVVIAARECGREGSELPPSGEETPGRR 389 +D P A+ C + G+ +P + + P ++ Sbjct: 1648 KDSPTSP--ASVTC-KMGATVPQASKGLPAKK 1676 Score = 52.0 bits (123), Expect = 1e-06 Identities = 61/247 (24%), Positives = 93/247 (37%), Gaps = 28/247 (11%) Query: 154 PPEPIPASAAVTSGLTARG----PNTSATPGPQKGRGSAERTNHIPKDKQRVAAPPP--- 206 P P+ AS + L+ +G P T+ +P P +G+ + P + V PP Sbjct: 827 PVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETP 886 Query: 207 -PERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRTRPLPRTSSFLSEVPSTRPLCATSSS 265 P +PF + G + P P + + T P+ + P+ + + A+ S Sbjct: 887 TPSVVNLPFPK--EGPATPAPKQAPA-----LSMTSSSPKKAR---ATPAPKGIPASPSP 936 Query: 266 HSAPLPFFWSPLRNPSPRPAPACGELRLGRLSPPRADTGGSSSGGCSGPDSKHRTLPAPP 325 AP P +P PSP+ PA + P A T S GG + P K AP Sbjct: 937 KGAPTPPAATP---PSPKGGPATPSPKWAPTPP--AATPPSPKGGPATPSPKG----APT 987 Query: 326 APTAWPAAGAPGAPNPAESRRGPGPAQGPPSRRDEPRRVVIAARECGREGSELPPSGEET 385 P A P + G P+ PA PPS + P + + PPS + + Sbjct: 988 PPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPF-PKGASTPPAATPPSPKGS 1046 Query: 386 PGRRKSP 392 P P Sbjct: 1047 PAATPLP 1053 Score = 52.0 bits (123), Expect = 1e-06 Identities = 75/306 (24%), Positives = 108/306 (35%), Gaps = 30/306 (9%) Query: 85 PASLSPRAALASAPGQKPQPARQAQLPRPVSGVRPPPRGRVGLSQAPGR------PLGAC 138 PA+ +P+ A+ P K P A P S PP +V S +P + P+GA Sbjct: 1447 PATSAPKGGPAT-PSSKGDPTLPAVTPP--SPKEPPAPKQVATSSSPKKAPATPAPMGAP 1503 Query: 139 ARAKGIRLVNPSPPRPPEPIPASAA--VTSGLTARGPNTSATPGPQKGRGSAERTNHIPK 196 + V PS P+ P+S + T T AT P++ T +P Sbjct: 1504 T----LPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMT--VPS 1557 Query: 197 DKQRVAAPPPPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRTRPLPRTSSFLSEVPST 256 K+ A P P E P P + +S TP + G K P TS E P T Sbjct: 1558 PKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAV-TSPSPKEAP-T 1615 Query: 257 RPLCATSSSHSAPLPFFWSPLRNPSPRPAPACGELRLGRL-SPPRADTGGSSSGGCSGPD 315 P S P P+P+ P + L P + + G + P Sbjct: 1616 PPAVTPPSPEKGP--------ATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQ 1667 Query: 316 SKHRTLPAPPAPTAWPAAGAPGAPNPAESRRGPGPAQGPPSRRDEPRRVVIAARECGREG 375 + + LPA PTA AP P +GP +++ I + G Sbjct: 1668 AS-KGLPAKKGPTALKEVLVAPAPESTPIITAP-TRKGPQTKKSSATSPPICPDPSAKNG 1725 Query: 376 SELPPS 381 S+ P S Sbjct: 1726 SKGPLS 1731 Score = 45.1 bits (105), Expect = 1e-04 Identities = 74/293 (25%), Positives = 95/293 (32%), Gaps = 39/293 (13%) Query: 134 PLGACARAKGIRLVNPSPPRPPEPIPASAAVTSGLT--------ARGPNTSATP--GPQK 183 PL A I PSP PP P G++ A P T G Sbjct: 720 PLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASA 779 Query: 184 GRGSAERTNHIPKDKQRVAAPPPPERPRVPFCRGSSG-------LSVPTPPEHAGGRRKK 236 S ++ + P+ R P +GS+G LS P P A Sbjct: 780 TASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEAS----- 834 Query: 237 FTRTRPLPRTSSFLSEVPSTRPLCATSSSHSAPLPFFWSPLRN------PSPRPAPACGE 290 F L S + P+T S AP P +PL P P P+ Sbjct: 835 FLPENSLSFQGS--KDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVN 892 Query: 291 LRLGRLSPPRADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAP-GAPNPAESRRGPG 349 L + P A + S S + A PAP PA+ +P GAP P + P Sbjct: 893 LPFPKEGP--ATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTP-PAATPPS 949 Query: 350 PAQGPPSRRDEPRRVVIAARECGREGSELPPS--GEETPGRRKSPSQSCKKGG 400 P GP + + AA +G PS G TP PS KGG Sbjct: 950 PKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPS---PKGG 999 >gi|116284398 WAS/WASL interacting protein family, member 1 [Homo sapiens] Length = 503 Score = 76.3 bits (186), Expect = 5e-14 Identities = 115/419 (27%), Positives = 145/419 (34%), Gaps = 90/419 (21%) Query: 33 PTLRHSAS------ALRPPRLSRG------KDLKPRCGRGPAHSPDPGEGCEAWRRLSAD 80 P LR +A+ RPP L G K P G G P PG R Sbjct: 109 PKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGH------RSGPP 162 Query: 81 RWPRPASLSPRAALASAPGQKPQPARQAQLPRPVSGVRPPPRGRVGLSQAPGRPLGACAR 140 R PR + S P P P PRP+ P R G PG P Sbjct: 163 EPQRNRMPPPRPDVGSKPDSIPPPVPST--PRPIQS---SPHNR-GSPPVPGGP------ 210 Query: 141 AKGIRLVNPSPPRPPEPIPASAAVTSGLTARGPNTSATP-------GPQKGRGSAER--- 190 R +P P PP P A+ G + P +S++P P R ++ Sbjct: 211 ----RQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPP 266 Query: 191 ----TNHIPKDKQRVAAPPPPER-----PRVPFCRGSSGLSVPTPPEHAGGRRKKFTRTR 241 + P + PPPP+ P P SS P PP G Sbjct: 267 PPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPG-------PP 319 Query: 242 PLPRTSSFLSEVPSTRPLCATSSSHSAPLPFFWSPLRN------PSPRPAPACGEL--RL 293 PLP +SS E P + SS + PLP SP R+ PS RP P + R Sbjct: 320 PLPPSSSGNDETPRLPQRNLSLSSSTPPLP---SPGRSGPLPPPPSERPPPPVRDPPGRS 376 Query: 294 GRLSPPR-ADTGGSSSGGC---------SGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAE 343 G L PP GS+S SG DS R+ P PP P P+AGAP P P+ Sbjct: 377 GPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSP-RSGPRPPLPPDRPSAGAPPPPPPST 435 Query: 344 SRRGPGPAQGPPSRRDEPRRVVIAARECGREGSELPPSGEETPGRRKSPSQSCKKGGES 402 S R +D P +R S+LPP + PS+ + S Sbjct: 436 SIRN--------GFQDSPCEDEWESRFYFHPISDLPPPEPYVQTTKSYPSKLARNESRS 486 >gi|38373695 WAS/WASL interacting protein family, member 1 [Homo sapiens] Length = 503 Score = 76.3 bits (186), Expect = 5e-14 Identities = 115/419 (27%), Positives = 145/419 (34%), Gaps = 90/419 (21%) Query: 33 PTLRHSAS------ALRPPRLSRG------KDLKPRCGRGPAHSPDPGEGCEAWRRLSAD 80 P LR +A+ RPP L G K P G G P PG R Sbjct: 109 PKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGH------RSGPP 162 Query: 81 RWPRPASLSPRAALASAPGQKPQPARQAQLPRPVSGVRPPPRGRVGLSQAPGRPLGACAR 140 R PR + S P P P PRP+ P R G PG P Sbjct: 163 EPQRNRMPPPRPDVGSKPDSIPPPVPST--PRPIQS---SPHNR-GSPPVPGGP------ 210 Query: 141 AKGIRLVNPSPPRPPEPIPASAAVTSGLTARGPNTSATP-------GPQKGRGSAER--- 190 R +P P PP P A+ G + P +S++P P R ++ Sbjct: 211 ----RQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPP 266 Query: 191 ----TNHIPKDKQRVAAPPPPER-----PRVPFCRGSSGLSVPTPPEHAGGRRKKFTRTR 241 + P + PPPP+ P P SS P PP G Sbjct: 267 PPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPG-------PP 319 Query: 242 PLPRTSSFLSEVPSTRPLCATSSSHSAPLPFFWSPLRN------PSPRPAPACGEL--RL 293 PLP +SS E P + SS + PLP SP R+ PS RP P + R Sbjct: 320 PLPPSSSGNDETPRLPQRNLSLSSSTPPLP---SPGRSGPLPPPPSERPPPPVRDPPGRS 376 Query: 294 GRLSPPR-ADTGGSSSGGC---------SGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAE 343 G L PP GS+S SG DS R+ P PP P P+AGAP P P+ Sbjct: 377 GPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSP-RSGPRPPLPPDRPSAGAPPPPPPST 435 Query: 344 SRRGPGPAQGPPSRRDEPRRVVIAARECGREGSELPPSGEETPGRRKSPSQSCKKGGES 402 S R +D P +R S+LPP + PS+ + S Sbjct: 436 SIRN--------GFQDSPCEDEWESRFYFHPISDLPPPEPYVQTTKSYPSKLARNESRS 486 >gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens] Length = 1120 Score = 64.7 bits (156), Expect = 1e-10 Identities = 92/356 (25%), Positives = 123/356 (34%), Gaps = 53/356 (14%) Query: 25 RLAEALSQPTLRHSASALRPPRLSRGKDLKP----RCGRGPAHSPD---PGEGCEAWRRL 77 RLAE L + L+ A + RL++G +L G GPA + +G E L Sbjct: 536 RLAE-LRRGLLQGEALSEGGRRLAKGPELMAIEGLENGEGPATAGPRLLTFQGSELSPEL 594 Query: 78 SA-------DRWPRPASLSPRAALASAPGQKPQPARQAQLPRPVSGVRPPPRGRVGLSQA 130 A + P P + SP A + +++ P+P G PP+ R L + Sbjct: 595 QAAMAGGGPEPLPLPPARSPSQESIGARSRGSGHSQEQPAPQPSGGDPSPPQER-NLPEG 653 Query: 131 PGRPLGACARAKGIRLVNPSPPRPPEPIPASAAVTSGLTARGPNTSATPGPQKGRGSAER 190 RP C+ G PP P +G +S PGP G A Sbjct: 654 TERPPKLCSSLPG-----QGPPPYVFMYP-----------QGSPSSPAPGPPPGAPWAFS 697 Query: 191 TNHIPKDKQRVAAPPPPERPRVPFCRGSSGLSVPTPPEH---------AGGRRKKFTRTR 241 P A PP P RP+ R S LS P P E G + Sbjct: 698 YLAGPP-----ATPPDPPRPK----RRSHSLSRPGPTEGDAEGEAEGPVGSTLGSYATLT 748 Query: 242 PLPRTSSFLSEVPSTRPLCATSSSHSAPLPFFWSPLRNPSPRPAPACGELRLGRLSPPRA 301 P S+ + PS P A + S + + P P P + PP Sbjct: 749 RRPGRSALVRTSPSVTPTPARGTPRSQSFALR-ARRKGPPPPPPKRLSSVSGPSPEPPPL 807 Query: 302 DTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAESRRGPGPAQGPPSR 357 D G +GP + RTL P P+ P AP P PGP PPSR Sbjct: 808 DESPGPKEGATGP--RRRTLSEPAGPSEPPGPPAPAGPASDTEEEEPGPEGTPPSR 861 Score = 55.5 bits (132), Expect = 9e-08 Identities = 74/328 (22%), Positives = 105/328 (32%), Gaps = 57/328 (17%) Query: 61 PAHSPDPGEGCEAWRRLSADRWPRPASLSPRAALASAPGQKPQPARQAQLPRPVSGVRPP 120 P+ +P P G + + + P L+S G P+P + P P G P Sbjct: 761 PSVTPTPARGTPRSQSFALRARRKGPPPPPPKRLSSVSGPSPEPPPLDESPGPKEGATGP 820 Query: 121 PRGRVGLSQAPGRPLGACARAKGIRLVNPSPPRPPEPIPASAAVTSGLTARGPNTSATPG 180 R + P P P PP P P + G P+ ++ Sbjct: 821 RRRTLSEPAGPSEP--------------PGPPAPAGPASDTEEEEPGPEGTPPSRGSS-- 864 Query: 181 PQKGRGSAERTNHIPKDKQRVAAPPPPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRT 240 +G AE N K + + A PPP E P P GL RR K Sbjct: 865 -GEGLPFAEEGNLTIKQRPKPAGPPPRETPVPP------GLDFNLTESDTVKRRPKCRER 917 Query: 241 RPLPRTSSFLSEVPSTRPLCATSSSHSAPLPFFWSPLRNPSPRPAPACGELRLGRLSPPR 300 PL +T+ V S P +APLP +P+P +P L P+ Sbjct: 918 EPL-QTALLAFGVASATP------GPAAPLP-------SPTPGESPPASSL-------PQ 956 Query: 301 ADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAESR--------RGPGPAQ 352 + + G P P+P P PG + A SR P Sbjct: 957 PEPSSLPAQGVPTP-----LAPSPAMQPPVPPCPGPGLESSAASRWNGETEPPAAPAALL 1011 Query: 353 GPPSRRDEPRRVVIAARECGREGSELPP 380 P P+ V +A + G +L P Sbjct: 1012 KVPGAGTAPKPVSVACTQLAFSGPKLAP 1039 Score = 30.0 bits (66), Expect = 4.0 Identities = 43/137 (31%), Positives = 48/137 (35%), Gaps = 32/137 (23%) Query: 24 PRLAEALSQPTLRHS--ASALRPPRLSR------GKDLKPRCGRGPAHSPDPGEGCEAWR 75 P A L PT S AS+L P S L P P P PG G E+ Sbjct: 934 PGPAAPLPSPTPGESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQPPVPPCPGPGLES-- 991 Query: 76 RLSADRW-------PRPASLSPRAALASAPGQKPQPARQAQL------------PRPVSG 116 +A RW PA+L +AP KP QL PRPV Sbjct: 992 -SAASRWNGETEPPAAPAALLKVPGAGTAP--KPVSVACTQLAFSGPKLAPRLGPRPVPP 1048 Query: 117 VRPPPRGRVGLSQAPGR 133 RP G VG QA R Sbjct: 1049 PRPESTGTVGPGQAQQR 1065 >gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens] Length = 1202 Score = 64.7 bits (156), Expect = 1e-10 Identities = 92/356 (25%), Positives = 123/356 (34%), Gaps = 53/356 (14%) Query: 25 RLAEALSQPTLRHSASALRPPRLSRGKDLKP----RCGRGPAHSPD---PGEGCEAWRRL 77 RLAE L + L+ A + RL++G +L G GPA + +G E L Sbjct: 618 RLAE-LRRGLLQGEALSEGGRRLAKGPELMAIEGLENGEGPATAGPRLLTFQGSELSPEL 676 Query: 78 SA-------DRWPRPASLSPRAALASAPGQKPQPARQAQLPRPVSGVRPPPRGRVGLSQA 130 A + P P + SP A + +++ P+P G PP+ R L + Sbjct: 677 QAAMAGGGPEPLPLPPARSPSQESIGARSRGSGHSQEQPAPQPSGGDPSPPQER-NLPEG 735 Query: 131 PGRPLGACARAKGIRLVNPSPPRPPEPIPASAAVTSGLTARGPNTSATPGPQKGRGSAER 190 RP C+ G PP P +G +S PGP G A Sbjct: 736 TERPPKLCSSLPG-----QGPPPYVFMYP-----------QGSPSSPAPGPPPGAPWAFS 779 Query: 191 TNHIPKDKQRVAAPPPPERPRVPFCRGSSGLSVPTPPEH---------AGGRRKKFTRTR 241 P A PP P RP+ R S LS P P E G + Sbjct: 780 YLAGPP-----ATPPDPPRPK----RRSHSLSRPGPTEGDAEGEAEGPVGSTLGSYATLT 830 Query: 242 PLPRTSSFLSEVPSTRPLCATSSSHSAPLPFFWSPLRNPSPRPAPACGELRLGRLSPPRA 301 P S+ + PS P A + S + + P P P + PP Sbjct: 831 RRPGRSALVRTSPSVTPTPARGTPRSQSFALR-ARRKGPPPPPPKRLSSVSGPSPEPPPL 889 Query: 302 DTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAESRRGPGPAQGPPSR 357 D G +GP + RTL P P+ P AP P PGP PPSR Sbjct: 890 DESPGPKEGATGP--RRRTLSEPAGPSEPPGPPAPAGPASDTEEEEPGPEGTPPSR 943 Score = 55.5 bits (132), Expect = 9e-08 Identities = 74/328 (22%), Positives = 105/328 (32%), Gaps = 57/328 (17%) Query: 61 PAHSPDPGEGCEAWRRLSADRWPRPASLSPRAALASAPGQKPQPARQAQLPRPVSGVRPP 120 P+ +P P G + + + P L+S G P+P + P P G P Sbjct: 843 PSVTPTPARGTPRSQSFALRARRKGPPPPPPKRLSSVSGPSPEPPPLDESPGPKEGATGP 902 Query: 121 PRGRVGLSQAPGRPLGACARAKGIRLVNPSPPRPPEPIPASAAVTSGLTARGPNTSATPG 180 R + P P P PP P P + G P+ ++ Sbjct: 903 RRRTLSEPAGPSEP--------------PGPPAPAGPASDTEEEEPGPEGTPPSRGSS-- 946 Query: 181 PQKGRGSAERTNHIPKDKQRVAAPPPPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRT 240 +G AE N K + + A PPP E P P GL RR K Sbjct: 947 -GEGLPFAEEGNLTIKQRPKPAGPPPRETPVPP------GLDFNLTESDTVKRRPKCRER 999 Query: 241 RPLPRTSSFLSEVPSTRPLCATSSSHSAPLPFFWSPLRNPSPRPAPACGELRLGRLSPPR 300 PL +T+ V S P +APLP +P+P +P L P+ Sbjct: 1000 EPL-QTALLAFGVASATP------GPAAPLP-------SPTPGESPPASSL-------PQ 1038 Query: 301 ADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAESR--------RGPGPAQ 352 + + G P P+P P PG + A SR P Sbjct: 1039 PEPSSLPAQGVPTP-----LAPSPAMQPPVPPCPGPGLESSAASRWNGETEPPAAPAALL 1093 Query: 353 GPPSRRDEPRRVVIAARECGREGSELPP 380 P P+ V +A + G +L P Sbjct: 1094 KVPGAGTAPKPVSVACTQLAFSGPKLAP 1121 Score = 30.0 bits (66), Expect = 4.0 Identities = 43/137 (31%), Positives = 48/137 (35%), Gaps = 32/137 (23%) Query: 24 PRLAEALSQPTLRHS--ASALRPPRLSR------GKDLKPRCGRGPAHSPDPGEGCEAWR 75 P A L PT S AS+L P S L P P P PG G E+ Sbjct: 1016 PGPAAPLPSPTPGESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQPPVPPCPGPGLES-- 1073 Query: 76 RLSADRW-------PRPASLSPRAALASAPGQKPQPARQAQL------------PRPVSG 116 +A RW PA+L +AP KP QL PRPV Sbjct: 1074 -SAASRWNGETEPPAAPAALLKVPGAGTAP--KPVSVACTQLAFSGPKLAPRLGPRPVPP 1130 Query: 117 VRPPPRGRVGLSQAPGR 133 RP G VG QA R Sbjct: 1131 PRPESTGTVGPGQAQQR 1147 >gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens] Length = 816 Score = 64.3 bits (155), Expect = 2e-10 Identities = 114/429 (26%), Positives = 144/429 (33%), Gaps = 92/429 (21%) Query: 11 SEEGRPTTESRIRPRLAEALSQPTLRHSASALRPPRLSRG-KDLKPRCG---RGPAHSPD 66 S R +R PR SQP + ALRPP+++ KD P G P +P Sbjct: 241 SSPARSGPSARGTPRAPAHPSQPKPK-GLQALRPPQVTPPRKDAAPALGPLSSSPLATPS 299 Query: 67 PGEGCEAWRRLSADRWPRPASLSPRAALASAPGQKPQPARQAQLPRPVSG--VRPPPRGR 124 P S P P + P A S G A + LP P PPP+ Sbjct: 300 PSAPPSPSAPPSLQTLPSPPATPPSQATTSL-GSPTLQATHSFLPSPPLSPLATPPPQAP 358 Query: 125 VGLS----QAPGRPLGA------------CARAKGIRLVN------PSPP-----RPPEP 157 L+ QAP P + A + L+ PSPP PP Sbjct: 359 PALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPAS 418 Query: 158 IPASAAVTSGLTA----RGPNTSATPGPQKGRGSAERTNHIPKDKQRVAAPP------PP 207 P S + T A P P P + P+ +AAPP PP Sbjct: 419 PPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPP 478 Query: 208 ERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRTRPLPRTSSFLSEVPSTRPLCATSSSHS 267 + P P ++P+PP G+ F+ + LP S + P P+ A Sbjct: 479 QAP--PALATPPLQALPSPPASFPGQAP-FSPSASLPM-SPLATPPPQAPPVLAAPLLQV 534 Query: 268 APLP----FFWSPLRNPSPRPAPACGELRL------GRLSPPRA---------DTGGSSS 308 P P +P R P+P P + RL G PP D G SS Sbjct: 535 PPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSS 594 Query: 309 ----------GGCSGPDSKHRTLPAPPA------PTAW------PAA--GAPGAPNPAES 344 G SGP+ P P A P AW P A GAPGAP P Sbjct: 595 SATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPP 654 Query: 345 RRGPGPAQG 353 GPG A G Sbjct: 655 ATGPGSADG 663 Score = 57.8 bits (138), Expect = 2e-08 Identities = 99/385 (25%), Positives = 136/385 (35%), Gaps = 89/385 (23%) Query: 43 RPPRLSRGKDLKPRCGRGPAHSPDPGEGCEAWR---------RLSADRW---------PR 84 RPP RG+ P P PG R R+SA+ P+ Sbjct: 84 RPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPK 143 Query: 85 PASLSP---RAALASAPGQ-KPQPARQAQ-------LPRPVSGVRPPPRGRVGLSQAPGR 133 ++LS R PG P AR+++ LPRP RP P ++ P + Sbjct: 144 RSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPP-----TEGPRK 198 Query: 134 PLGACARAKGIRLVNPSPPRPPEPI-------PASAAVTSGLTA------RGPNTSATPG 180 + + + PSP P PAS +++S T GP+ TP Sbjct: 199 SVSSASEHS---TTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTP- 254 Query: 181 PQKGRGSAERTNHIPKDKQRVAAPP--PPERPRVPFCR--GSSGLSVPTPPEHAGGRRKK 236 R A + PK Q + P PP + P SS L+ P+P Sbjct: 255 ----RAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 Query: 237 FTRTRPLPRTSSFLSEVPSTRPLCATSS--------SHS-APLPFFWSPLRNPSPRPAPA 287 +T P P P+T P AT+S +HS P P SPL P P+ PA Sbjct: 311 SLQTLPSP---------PATPPSQATTSLGSPTLQATHSFLPSPPL-SPLATPPPQAPPA 360 Query: 288 CGELRLGRLSPPRADTGGSSSGGCSGPDSKH------RTLPAPPAPTAWPAAGAPGAP-- 339 L L L P + + P + L AP +P P AP +P Sbjct: 361 ---LALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA 417 Query: 340 NPAESRRGPGPAQGPPSRRDEPRRV 364 +P S P+Q PPS P +V Sbjct: 418 SPPVSPSATPPSQAPPSLAAPPLQV 442 Score = 55.1 bits (131), Expect = 1e-07 Identities = 90/329 (27%), Positives = 119/329 (36%), Gaps = 42/329 (12%) Query: 86 ASLSPRAALASAPGQ-KPQPARQAQLPRPVSGVRPPPRGRVGLSQAPGR-PLGACARAKG 143 A + R A APG P+P PRP V P +G + A GR PL A G Sbjct: 10 AGAAARTPAARAPGLLTPRPPGS---PRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIG 66 Query: 144 IRLVNPSPPRPPEPIPASAAVTSGLTARGP---NTSATPGPQKGRGSAE-RTNHIPKDKQ 199 + S PR P S SG R P NTS P GR S R + + Sbjct: 67 GATIPESAPRAG-PTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGL 125 Query: 200 RVAAPPPPERPRVPFCRGSSGLSV--------PTP--PEHAGGRRKKFTRTRP-LPRTSS 248 R++A R + S LS PTP P A RR + T LPR + Sbjct: 126 RISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAP 185 Query: 249 FLSEVPST---RPLCATSSSHSAPLPFFWSPLRNPSPRPAPACGELRLGRLSPPRADTGG 305 P T R +++S HS P +P+ R P+ G G L P + + Sbjct: 186 SARPRPPTEGPRKSVSSASEHSTTEP-------SPAARRRPSAG----GGLQRPASRSLS 234 Query: 306 SSSGGCSGPDSKHRTLPAPPAPTAWPAAGA-PGAPNPAESRRGPGPAQGPPSRRDEPRRV 364 SS+ S P + P+ P A A P P P + P PP + P Sbjct: 235 SSATPLSSPAR------SGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALG 288 Query: 365 VIAARECGREGSELPPSGEETPGRRKSPS 393 +++ PPS P + PS Sbjct: 289 PLSSSPLATPSPSAPPSPSAPPSLQTLPS 317 Score = 55.1 bits (131), Expect = 1e-07 Identities = 85/303 (28%), Positives = 112/303 (36%), Gaps = 46/303 (15%) Query: 83 PRPASLSPRAALASAPGQKPQPARQAQLPRPVSGVRPPPRGRVGLSQAPGRPLGACARAK 142 PR AS G++ PA+ P PVS GR + PG PLG K Sbjct: 75 PRAGPTRTSRPPASGRGERAPPAKNTS-PGPVSSP-----GRASGTTRPG-PLGQ----K 123 Query: 143 GIRLVNPSPPRPPEPI--PASAAVTSGLT--ARGPNTSATPGPQKGRGSAERTNHI--PK 196 G+R+ + P +A+++G GP T TP P R S + P+ Sbjct: 124 GLRISAEETVARGKATEAPKRSALSAGARRDTSGP-TPGTPSPAMARRSRAAGTEVGLPR 182 Query: 197 DKQRVAAPPPPERPRVPFCRGSS-GLSVPTP-----PEHAGGRRKKFTRTRPLPRT--SS 248 PP E PR S + P+P P GG ++ +R+ T SS Sbjct: 183 PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSS 242 Query: 249 FLSEVPSTRPLCATSSSHSAPLPFFWSPLRNPSPRP-----APACGELRLGRLSPPRADT 303 PS R + S P P LR P P APA G L S P A Sbjct: 243 PARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLS----SSPLATP 298 Query: 304 GGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAPGA----------PNPAESRRGPGPAQG 353 S+ S P S +TLP+PPA A + G+ P+P S P Q Sbjct: 299 SPSAPPSPSAPPSL-QTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQA 357 Query: 354 PPS 356 PP+ Sbjct: 358 PPA 360 Score = 53.1 bits (126), Expect = 4e-07 Identities = 83/318 (26%), Positives = 115/318 (36%), Gaps = 69/318 (21%) Query: 83 PRPASLSPRAALASA---------PGQKPQPARQAQLPRPVSG------------VRPPP 121 PRP + PR +++SA P + +P+ L RP S R P Sbjct: 189 PRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGP 248 Query: 122 RGRVGLSQAPGRPLGACARAKGIRLVNPSPPRPP--EPIPASAAVTSGLTARGPNTSATP 179 R G +AP P + + KG++ + P PP + PA ++S A P+ SA P Sbjct: 249 SAR-GTPRAPAHP--SQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLAT-PSPSAPP 304 Query: 180 GPQKGRGSAERTNHIPKDKQRVAAPPPPERPRVPFCRGSSGLS-----VPTPPEHAGGRR 234 P P Q + +PP + GS L +P+PP Sbjct: 305 SPSA-----------PPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSP---- 349 Query: 235 KKFTRTRPLPRTSSFLSEVPSTRPLCATSSSHSAPLPFFWSPLRNPSPRP--APACGELR 292 P P+ L+ P P S S PL SPL PSP+ A A L+ Sbjct: 350 ----LATPPPQAPPALALPPLQAP---PSPPASPPL----SPLATPSPQAPNALAVHLLQ 398 Query: 293 LGRLSPPRADTGGSSSGGCSGPDSKHRTLP--APPAPTA-------WPAAGAPGAPNPAE 343 PP S S P S T P APP+ A P A P +P+ Sbjct: 399 APFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATP 458 Query: 344 SRRGPGPAQGPPSRRDEP 361 + P P PP + +P Sbjct: 459 PPQAPPPLAAPPLQLAKP 476 Score = 52.0 bits (123), Expect = 1e-06 Identities = 95/362 (26%), Positives = 126/362 (34%), Gaps = 69/362 (19%) Query: 16 PTTESRIRPRLAEALSQPTLRHSASALRP-PRLSRGKDLKPRCGRGPAHSPDPG-EGCEA 73 P+ +R RP L +P R +S+ P +R R PAH P +G +A Sbjct: 211 PSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQA 270 Query: 74 WR-------RLSADRWPRPASLSPRAALA-SAPGQKPQPARQAQLPRPVSGVRPPPRGRV 125 R R A P S SP A + SAP P LP P + PP + Sbjct: 271 LRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPA--TPPSQATT 328 Query: 126 GL---------SQAPGRPLGACARAKGIRLVNPSPPRPPE-PIPASAAVTSGLTARGPNT 175 L S P PL L P P PP +P A S + + Sbjct: 329 SLGSPTLQATHSFLPSPPLSP--------LATPPPQAPPALALPPLQAPPSPPASPPLSP 380 Query: 176 SATPGPQKGRGSAERTNHIPKDKQRVAAPPPPERPRVPFCRGSSGLSVP--TPPEHAGGR 233 ATP PQ A P +PPP + PF +S P TPP A Sbjct: 381 LATPSPQAPNALAVHLLQAP------FSPPPSPPVQAPFSPPASPPVSPSATPPSQAP-- 432 Query: 234 RKKFTRTRPLPRTSSFLSEVPSTRPLCATSSSHSAPLPFFWSPLRNPSPRPAPACGELRL 293 P ++ +VP + P S + P P + P P AP L+L Sbjct: 433 ----------PSLAAPPLQVPPSPPASPPMSPSATPPP------QAPPPLAAPP---LQL 473 Query: 294 GRLSPPRADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAESRRGPGPAQG 353 + PP+A ++ + LP+PPA A +P A P P P Q Sbjct: 474 AK-PPPQAPPALATP--------PLQALPSPPASFPGQAPFSPSASLPMSPLATP-PPQA 523 Query: 354 PP 355 PP Sbjct: 524 PP 525 Score = 35.4 bits (80), Expect = 0.096 Identities = 42/150 (28%), Positives = 55/150 (36%), Gaps = 21/150 (14%) Query: 261 ATSSSHSAPLPFFWSPLRNPSPRPAPACGELRLGRLSP-------PRADTGGSSSGGCSG 313 A + + +A P +P SPRP P L L P A+ G GG + Sbjct: 12 AAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGI-GGATI 70 Query: 314 PDSKHRTLPAPPAPTAWPAAGAPGAPNPAESRRGPGPAQGPPSRRDEPRRVVIAARECGR 373 P+S R A P T+ P A G P PGP P R G+ Sbjct: 71 PESAPR---AGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTR-----PGPLGQ 122 Query: 374 EGSELPPSGEETPGRRK---SPSQSCKKGG 400 +G + S EET R K +P +S G Sbjct: 123 KGLRI--SAEETVARGKATEAPKRSALSAG 150 >gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] Length = 416 Score = 63.9 bits (154), Expect = 3e-10 Identities = 92/377 (24%), Positives = 127/377 (33%), Gaps = 68/377 (18%) Query: 44 PPRLSRGKDLKPRCGRGPAHSPDPGEGCEAWRRLSADRWPRPA---SLSPRAALASAPGQ 100 PP + + P+ G P P PG+ + P P S SPR+ G Sbjct: 72 PPPPGKPQGPPPQGGNKPQGPPPPGK----------PQGPPPQGDKSRSPRSPPGKPQGP 121 Query: 101 KPQPARQAQLPRPVSGVR--PPPRG--RVGLSQAPGRPLGACARAKGIRLVNPSPPRPPE 156 PQ Q Q P P G PPP+G + PG+P G + + SPP P+ Sbjct: 122 PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQ 181 Query: 157 PIPASAAVTSGLTARGPNTSATPGPQKGRGSAERTNHIPKDKQRVAAPPPPERPRVPFCR 216 P G +GP P P K +G + + P+ PPPP +P+ P + Sbjct: 182 GPPPQG----GNQPQGP----PPPPGKPQGPPPQGGNKPQ------GPPPPGKPQGPPPQ 227 Query: 217 GSS-GLSVPTPPEHAGGRRKKFTRTRPLPRTSSFLSEVPSTRPLCATSSSHSAPLPFFWS 275 G + S +PP G P P+ + + P P P P + Sbjct: 228 GDNKSQSARSPPGKPQG---------PPPQGGN-QPQGPPPPP-----GKPQGPPPQGGN 272 Query: 276 PLRNPSPR-----PAPACGELRLGRLSPPRADTGGSSSGGCSGPDSKHRTLPAPPAPTAW 330 + P P P P G SPP G GG PP P Sbjct: 273 KPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGG--------NQPQGPPPPPGK 324 Query: 331 PAAGAPGAPNPAESRRGPGPAQGPP--------SRRDEPRRVVIAARECGREGSELPPSG 382 P P N + PG QGPP S R P + ++ G PP Sbjct: 325 PQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPA 384 Query: 383 EETPGRRKSPSQSCKKG 399 P + ++P +G Sbjct: 385 GGNPQQPQAPPAGQPQG 401 Score = 55.5 bits (132), Expect = 9e-08 Identities = 79/321 (24%), Positives = 108/321 (33%), Gaps = 56/321 (17%) Query: 89 SPRAALASAPGQKPQPARQAQLPRPVSGVR--PPPRGR---VGLSQAPGRPLGACARAKG 143 SP + G PQ + Q P G PPP+G G PG+P G + G Sbjct: 28 SPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG-G 86 Query: 144 IRLVNPSPPRPPEPIPASAAVTSGLTARGPNTSATPGPQKGRGSAERTNHIPKDKQRVAA 203 + P PP P+ P G +R P + P K +G + + P+ Sbjct: 87 NKPQGPPPPGKPQGPPPQ-----GDKSRSPRSP----PGKPQGPPPQGGNQPQ-----GP 132 Query: 204 PPPPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRTRPLPRTSSFLSEVPSTRPLCATS 263 PPPP +P+ P +G + P PP G P S S P +P Sbjct: 133 PPPPGKPQGPPPQGGNKPQGPPPPGKPQG-------PPPQGDNKSRSSRSPPGKP----- 180 Query: 264 SSHSAPLPFFWSPLRNPSPRPAPACGELRLG-------------RLSPPRADTGGSSS-- 308 P P + + P P P G G + PP+ D S+ Sbjct: 181 ---QGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARS 237 Query: 309 --GGCSGPDSKHRTLP-APPAPTAWPAAGAPGAPNPAESRRGPGPAQGPPSRRDEPRRVV 365 G GP + P PP P P P N + PG QGPP + R Sbjct: 238 PPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSR-- 295 Query: 366 IAARECGREGSELPPSGEETP 386 ++R + PP G P Sbjct: 296 -SSRSPPGKPQGPPPQGGNQP 315 Score = 36.2 bits (82), Expect = 0.056 Identities = 32/117 (27%), Positives = 39/117 (33%), Gaps = 12/117 (10%) Query: 279 NPSPRPAPACGELRLGRLSPPRADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAPGA 338 NP P P G G SPP G GG PP P P P Sbjct: 35 NPQGAP-PQGGNKPQGPPSPPGKPQGPPPQGG--------NQPQGPPPPPGKPQGPPPQG 85 Query: 339 PNPAESRRGPGPAQGPPSRRDE---PRRVVIAARECGREGSELPPSGEETPGRRKSP 392 N + PG QGPP + D+ PR + +G P PG+ + P Sbjct: 86 GNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP 142 >gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 preproprotein [Homo sapiens] Length = 331 Score = 62.4 bits (150), Expect = 7e-10 Identities = 83/322 (25%), Positives = 114/322 (35%), Gaps = 52/322 (16%) Query: 44 PPRLSRGKDLKPRCGRGPAHSPDPGEGCEAWRRLSADRWPRPA---SLSPRAALASAPGQ 100 PP + + P+ G P P PG+ + P P S SPR+ G Sbjct: 51 PPPPGKPQGPPPQGGNKPQGPPPPGK----------PQGPPPQGDKSRSPRSPPGKPQGP 100 Query: 101 KPQPARQAQLPRPVSGVR--PPPRG--RVGLSQAPGRPLGACARAKGIRLVNPSPPRPPE 156 PQ Q Q P P G PPP+G R PG+P G + R P +P Sbjct: 101 PPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQG 160 Query: 157 PIPASAAVTSGLTARGPNTSATPGPQKGRGSAERTNHIPKDKQRVAAPPPPERPRVPFCR 216 P P G +GP P P K +G P+ ++ PPPP +P+ P + Sbjct: 161 PPPQG-----GNQPQGP----PPPPGKPQGPP------PQGGKKPQGPPPPGKPQGPPPQ 205 Query: 217 GSSGLSVPTPPEHAGGRRKKFTRTRPLPRTSSFLSEVPSTRPLCATSSSHSAPLPFFWSP 276 G S +PP G P P+ + + P P P P + Sbjct: 206 GDKSRSSQSPPGKPQG---------PPPQGGN-QPQGPPPPP-----GKPQGPPPQGGNK 250 Query: 277 LRNPSPRPAPACGELRLGRLSPPRADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAP 336 + P P P + G ++ + S G GP + P P P A P Sbjct: 251 PQGPPPPGKPQGPPAQGGS----KSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQP 306 Query: 337 GAPNPAESRRGPGPAQ-GPPSR 357 AP + + P P Q G PSR Sbjct: 307 QAPPAGQPQGPPRPPQGGRPSR 328 Score = 60.1 bits (144), Expect = 4e-09 Identities = 81/327 (24%), Positives = 110/327 (33%), Gaps = 54/327 (16%) Query: 89 SPRAALASAPGQKPQPARQAQLPRPVSGVR--PPPRG--RVGLSQAPGRPLGACARAKGI 144 SP + G PQ + Q P P G PPP+G + PG+P G + Sbjct: 28 SPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKS 87 Query: 145 RLVNPSPPRPPEPIPASAAVTSGLTARGPNTSATPGPQKGRGSAERTNHIPKDKQRVAAP 204 R P +P P P G +GP P P K +G P+ R P Sbjct: 88 RSPRSPPGKPQGPPPQG-----GNQPQGP----PPPPGKPQGPP------PQGGNRPQGP 132 Query: 205 PPPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRTRPLPRTSSFLSEVPSTRPLCATSS 264 PPP +P+ P +G S +PP G P P+ + + P P Sbjct: 133 PPPGKPQGPPPQGDKSRSPRSPPGKPQG---------PPPQGGN-QPQGPPPPP-----G 177 Query: 265 SHSAPLPFFWSPLRNPSPRPAPACGELRLGRLSPPRADTGGSSS---GGCSGPDSKHRTL 321 P P + P P P + PP+ D SS G GP + Sbjct: 178 KPQGPPPQGGKKPQGPPPPGKP--------QGPPPQGDKSRSSQSPPGKPQGPPPQGGNQ 229 Query: 322 P-APPAPTAWPAAGAPGAPNPAESRRGPGPAQGPP--------SRRDEPRRVVIAARECG 372 P PP P P P N + PG QGPP S R P + ++ G Sbjct: 230 PQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEG 289 Query: 373 REGSELPPSGEETPGRRKSPSQSCKKG 399 PP P + ++P +G Sbjct: 290 NNPQGPPPPAGGNPQQPQAPPAGQPQG 316 >gi|158854042 hypothetical protein LOC222183 [Homo sapiens] Length = 653 Score = 61.2 bits (147), Expect = 2e-09 Identities = 75/313 (23%), Positives = 112/313 (35%), Gaps = 27/313 (8%) Query: 33 PTLRHSASALRPPRLSRGKDLKPRCGRGPAHSPDPGEGCEAWRRLSADRWPRPASLSPRA 92 P +R A+A P +RGK+ P P+ G R R R S S + Sbjct: 343 PRVRDKAAAAAPTPPARGKE-SPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSAS 401 Query: 93 ALASAPGQKPQPARQAQLPRPVSGVRPPP-----RGRVGLSQAPGRPLGACARAKGIRLV 147 A ++P+PA R +S R RG G PG G K + Sbjct: 402 APRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAK-- 459 Query: 148 NPSPPRPPEPIPASAAVTSGLTAR-----GPNTSATPGPQKGRGSAERTNHIPKDKQRVA 202 RPP PAS + + G R G ++S +PGP S+ R+ + + Sbjct: 460 ----ERPPRARPASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEK 515 Query: 203 APPPPER---PRVPFCRGSSGLSVPTPPEHAGGRRKKFTRTRPLPRTSSFLSEVPSTRPL 259 P P R P+ P R G E R ++ R+R + PS Sbjct: 516 RPHSPSRSPSPKKPLSRDKDGEGRARHSEAEATRARR--RSRSYSPIRKRRRDSPSFMEP 573 Query: 260 CATSSSHSAPLPFFWSPLRNPSPRPAPACGELRLGRLSPPRADTGGSSSGGCSGPDSKHR 319 +S+ P+P++ PSP + +C S R+ + G S G S R Sbjct: 574 RRITSARKRPIPYY-----RPSPSSSSSCLSSDYSTRSHSRSPSPGHSHGSYSSRSHGTR 628 Query: 320 TLPAPPAPTAWPA 332 + P+ T P+ Sbjct: 629 SRTRSPSRTPSPS 641 Score = 51.6 bits (122), Expect = 1e-06 Identities = 74/292 (25%), Positives = 106/292 (36%), Gaps = 58/292 (19%) Query: 150 SPPRPPEPIPASAAVTSGLTARGPNTSATPG---PQKGRGSAERTN---------HIP-- 195 SP E + +SG +R P+ S G PQ+ GS +R+ H P Sbjct: 279 SPKHRDEGRKTGSQRSSG--SRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPD 336 Query: 196 ---------KDKQRVAAPPPPERPRVPFCRGSSGLSVPTPPEHAG------GRRKKFTRT 240 +DK AAP PP R + S S P+ G GRR++ R Sbjct: 337 KPSSPSPRVRDKAAAAAPTPPARGK----ESPSPRSAPSSQGRGGRAAGGAGRRRRRRRR 392 Query: 241 RPLPRTSSFLSEV-----PSTRPLCATSSSHSAPLPFFWSPLRNPSPRPAPACGELR--- 292 R R+S+ P P +S S S S +P P P G R Sbjct: 393 RRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHG 452 Query: 293 ----LGRLSPPRADTGGSSS-----GGCSGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAE 343 + PPRA +S G GP+ K + P P +W ++ +P Sbjct: 453 GHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRS 512 Query: 344 SRRGPGPAQGPPSRRDEPRRVVIAARECGREGSELPPSGEETPGRRKSPSQS 395 + + P PSR P++ + +R+ EG E T RR+S S S Sbjct: 513 AEKRP----HSPSRSPSPKKPL--SRDKDGEGRARHSEAEATRARRRSRSYS 558 Score = 39.3 bits (90), Expect = 0.007 Identities = 62/254 (24%), Positives = 91/254 (35%), Gaps = 42/254 (16%) Query: 187 SAERTNHIPKDKQRVAAPPPPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRTRPLPRT 246 S R + +D+ R R P G SG P+ GG ++ P + Sbjct: 274 SPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWG---SPQRNGGSGQRSGAHGGRPGS 330 Query: 247 SSFLSEVPST-RPLCATSSSHSAPLPFFWSPLR---NPSPRPAPACGELRLGRLSPP--- 299 + + PS+ P ++ +AP P P R +PSPR AP+ + R GR + Sbjct: 331 AHSPPDKPSSPSPRVRDKAAAAAPTP----PARGKESPSPRSAPS-SQGRGGRAAGGAGR 385 Query: 300 -----RADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAESRRGPGPAQGP 354 R SS + R PAPP ++ + A + + R PGP P Sbjct: 386 RRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRGAPGPGPEP 445 Query: 355 PSRR----------DEPRRVVIAARE-----CGREGSELPPSGEETPG-------RRKSP 392 S R + P R A+ GR G S +PG +SP Sbjct: 446 GSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSP 505 Query: 393 SQSCKKGGESILHS 406 S+S + E HS Sbjct: 506 SKSRSRSAEKRPHS 519 Score = 37.4 bits (85), Expect = 0.025 Identities = 43/150 (28%), Positives = 57/150 (38%), Gaps = 33/150 (22%) Query: 233 RRKKFTRTRPLPRTSSFLSEVPSTRPLCATS-SSHSAPLPFFWSPLRNPS---PR----- 283 +RK+ + + P T S P R +S SSHS L +S R+PS P+ Sbjct: 232 KRKEKNKEKKRPHTES-----PGRRSHRHSSGSSHSPSLSSHYSDSRSPSRLSPKHRDEG 286 Query: 284 -------------PAPACGELRLGRLSPPRADTGGSSSGGCSG-PDSKHRT--LPAPPAP 327 P+P+ G G SP R G SG G P S H P+ P+P Sbjct: 287 RKTGSQRSSGSRSPSPSGGS---GWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKPSSPSP 343 Query: 328 TAWPAAGAPGAPNPAESRRGPGPAQGPPSR 357 A A PA + P P P S+ Sbjct: 344 RVRDKAAAAAPTPPARGKESPSPRSAPSSQ 373 >gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens] Length = 2161 Score = 60.8 bits (146), Expect = 2e-09 Identities = 91/318 (28%), Positives = 109/318 (34%), Gaps = 53/318 (16%) Query: 63 HSPDPGEGCEAWRRLSADRWPRPA--SLSPRAALASA----PGQKPQPARQA--QLPRPV 114 H P E RL P PA L RA L S P P R +LP Sbjct: 1393 HHHSPHAHHEPVLRLWGASPPDPARRELGYRAGLGSQEKSLPASPPAARRSLLHRLPPTA 1452 Query: 115 SGVRP--------PPRGRVGLSQAPGRPLGACARAKGIRLVNPSPPRPPEPIPASAAVTS 166 GV P PP G+S +P + A + RL P R E A VTS Sbjct: 1453 PGVGPLLLQLGTEPPAPHPGVS----KPWRSAAPEEPERL--PLHVRFLENCQPRAPVTS 1506 Query: 167 GLTARGPNTSATPGPQKGRGSAERTNHIPKDKQRVAAPPPPERPRVPFCRGSSGLSVPTP 226 G RGP + PG +P R + PP P PR G L +P P Sbjct: 1507 G---RGPPSEDGPG-------------VPPPSPRRSVPPSPTSPRASEENGLPLLVLPPP 1550 Query: 227 PEHAGGRRKKFTRTRPLPRTSSFLSEVPSTRPLCATSSSHSAPLPFFWSPLRNPSPRPAP 286 +F PLP F + H PLP +P P P P Sbjct: 1551 APSVDVEDGEFLFVEPLPPPLEFSNSFEKPESPLTPGPPH--PLPDTPAPATPLPPVPPP 1608 Query: 287 ACGELRLGRLSPPRADTGGSSSGGCSGPDSKHRTLP----APPAPTAWPAAGAPGAPNPA 342 A +PP D+ SS + DS+ TL A P P AP AP PA Sbjct: 1609 AVAA------APPTLDSTASS---LTSYDSEVATLTQGASAAPGDPHPPGPPAPAAPAPA 1659 Query: 343 ESRRGPGPAQGPPSRRDE 360 + GP P G S +E Sbjct: 1660 APQPGPDPPPGTDSGIEE 1677 Score = 42.7 bits (99), Expect = 6e-04 Identities = 70/293 (23%), Positives = 105/293 (35%), Gaps = 37/293 (12%) Query: 120 PPRGRVGLSQ---APGRPLGACARAKGIRLVNPSP-PRPPEPIPASAAVTSGLTARGPNT 175 PP G S P LG +G R PSP P P P +A G +++GP Sbjct: 1023 PPEMETGGSPDDPPPRLALGPQPSLRGWRGGGPSPTPGAPSPSHHGSAGGGGGSSQGPAL 1082 Query: 176 SATPGPQKGRGSAERTNHIPKDKQRVAAPPPPERPRVPFCRGSSGLSVPTPPEHAGGRRK 235 P + +A ++P R P ++ +V P+ GG Sbjct: 1083 RYFQLPPRAASAAM---YVPARSGRGRKGPLVKQTKVE-----------GEPQKGGG--- 1125 Query: 236 KFTRTRPLPRTSSFLSEVPSTRPLCATSSSHSAPLPFFWSPLRNPSPRPAPACGELRLGR 295 P P +S S P + A S +S P+P ++ PS + + Sbjct: 1126 ----LPPAPSPTSPASPQPPPA-VAAPSEKNSIPIPTII--IKAPSTSSSGRSSQGSSTE 1178 Query: 296 LSPP-RADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAESRRGPGPAQGP 354 PP + + G GG S P P PP+P+ P +P P + G A Sbjct: 1179 AEPPTQPEPTGGGGGGGSSPSPAPAMSPVPPSPSPVPTPASPSGPATLDFTSQFGAALVG 1238 Query: 355 PSRRD-----EPRR--VVIAARECGRE-GSELPPSGEETPGRRKSPSQSCKKG 399 +RR+ E RR + + + G E G + PG R S+S +G Sbjct: 1239 AARREGGWQNEARRRSTLFLSTDAGDEDGGDGGLGTGAAPGPRLRHSKSIDEG 1291 Score = 39.3 bits (90), Expect = 0.007 Identities = 55/213 (25%), Positives = 78/213 (36%), Gaps = 37/213 (17%) Query: 44 PPRLSRGKDLKPRCGRGPAHSPDPGEGCEAWRRLS-----ADRWP--RPASLSPRAALA- 95 PPRL+ G R RG SP PG + + + + P R L PRAA A Sbjct: 1036 PPRLALGPQPSLRGWRGGGPSPTPGAPSPSHHGSAGGGGGSSQGPALRYFQLPPRAASAA 1095 Query: 96 ------SAPGQKPQPARQAQL---PRPVSGVRPPPRGRVGLSQAPGRPLGACARAKGIRL 146 S G+K +Q ++ P+ G+ P P S P + A + I Sbjct: 1096 MYVPARSGRGRKGPLVKQTKVEGEPQKGGGLPPAPSPTSPASPQPPPAVAAPSEKNSI-- 1153 Query: 147 VNPSPPRPPEPIPASAAVTSGLTARGPNTSATPGPQ-KGRGSAERTNHIPKDKQRVAAPP 205 P P I A + +SG +++G +T A P Q + G P ++ P Sbjct: 1154 -----PIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQPEPTGGGGGGGSSPSPAPAMSPVP 1208 Query: 206 PPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFT 238 P P VPTP +G FT Sbjct: 1209 PSPSP------------VPTPASPSGPATLDFT 1229 Score = 37.4 bits (85), Expect = 0.025 Identities = 62/249 (24%), Positives = 76/249 (30%), Gaps = 53/249 (21%) Query: 120 PPRGRV----GLSQAPGRPLGACARAKGIRLVNPS--------PPRPPEPIPASAAVTSG 167 PPR V G + P PLG A+ L S PPRPP P Sbjct: 1334 PPRPLVHPLTGKALDPASPLGLALAARERALKESSEGGGAPQPPPRPPSP---------- 1383 Query: 168 LTARGPNTSATPGPQKGRGSAERTNHIPKDKQRVAAPPPPERPRVPFCRGSSGLSVPTPP 227 P P S +H P + A+PP P R + + G P Sbjct: 1384 -------RYEAPPPTPHHHSPH-AHHEPVLRLWGASPPDPARRELGYRAGLGSQEKSLPA 1435 Query: 228 EHAGGRRKKFTRTRPL-----PRTSSFLSEVPSTRPLCATSSSHSAP-----LPFFWSPL 277 RR R P P +E P+ P + +AP LP L Sbjct: 1436 SPPAARRSLLHRLPPTAPGVGPLLLQLGTEPPAPHPGVSKPWRSAAPEEPERLPLHVRFL 1495 Query: 278 RNPSPRPAPACGELRLGRLSPPRADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAP- 336 N PR G PP D G P + P+P +P A G P Sbjct: 1496 ENCQPRAPVTSGR------GPPSED-----GPGVPPPSPRRSVPPSPTSPRASEENGLPL 1544 Query: 337 -GAPNPAES 344 P PA S Sbjct: 1545 LVLPPPAPS 1553 Score = 37.0 bits (84), Expect = 0.033 Identities = 57/251 (22%), Positives = 73/251 (29%), Gaps = 46/251 (18%) Query: 149 PSPPRPPEPIPASAAVTSGLTARGPNTSATPGPQKGRGSAERTNHIPKDKQRVAAPPPPE 208 P PP P+P+S+ TP P+ G + +P P P Sbjct: 929 PEPPYSTPPVPSSSG------------RLTPSPRGGPFNPGSGGPLPASSPASFDGPSPP 976 Query: 209 RPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRTRPLPRTSSFLSEVPSTRPLCATSSSHSA 268 RV S S P PP H P P+ + P + S Sbjct: 977 DTRVGSREKSLYHSGPLPPAHHHPPHHHHHHAPP-PQPHHHHAHPPHPPEMETGGSPDDP 1035 Query: 269 PLPFFWSP------LRNPSPRPAPACGELRLGRLSPPRADTGGSSSGGCSGPDSKHRTLP 322 P P R P P P G SP + G G GP ++ LP Sbjct: 1036 PPRLALGPQPSLRGWRGGGPSPTP-------GAPSPSHHGSAGGGGGSSQGPALRYFQLP 1088 Query: 323 APPAPTAWPAAGAPGAPNPAESRRG-PGPAQGPPSRRDEPRRVVIAARECGREGSELPPS 381 P A + PA S RG GP EP++ G LPP+ Sbjct: 1089 --------PRAASAAMYVPARSGRGRKGPLVKQTKVEGEPQK-----------GGGLPPA 1129 Query: 382 GEETPGRRKSP 392 T P Sbjct: 1130 PSPTSPASPQP 1140 Score = 32.3 bits (72), Expect = 0.81 Identities = 50/194 (25%), Positives = 61/194 (31%), Gaps = 22/194 (11%) Query: 179 PGPQKGRGSAERTNHIPKDKQRVAAPPPPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFT 238 P G A R + + + AP PP RP P PTP H+ Sbjct: 1349 PASPLGLALAARERALKESSEGGGAPQPPPRPPSPRYEAPP----PTPHHHS-----PHA 1399 Query: 239 RTRPLPRTSSFLSEVPSTRP------LCATSSSHSAPLPFFWSPLRNPSPRPAPACGELR 292 P+ R P+ R L + S A P L + P AP G L Sbjct: 1400 HHEPVLRLWGASPPDPARRELGYRAGLGSQEKSLPASPPAARRSLLHRLPPTAPGVGPLL 1459 Query: 293 LG-RLSPPRADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAESRRGPGPA 351 L PP G S + P+ R P + P A P S RGP Sbjct: 1460 LQLGTEPPAPHPGVSKPWRSAAPEEPERL----PLHVRFLENCQPRA--PVTSGRGPPSE 1513 Query: 352 QGPPSRRDEPRRVV 365 GP PRR V Sbjct: 1514 DGPGVPPPSPRRSV 1527 Score = 31.6 bits (70), Expect = 1.4 Identities = 39/149 (26%), Positives = 51/149 (34%), Gaps = 20/149 (13%) Query: 205 PPPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRTRPLPRTS-----SFLSEVPSTRPL 259 P P P +P G S + P + T TR L L PS P Sbjct: 1945 PKPPLPPLPTGTGVSPTAAAAPGATSPSASSSSTSTRHLQGVEFEMRPPLLRRAPS--PS 2002 Query: 260 CATSSSHSAPLPFFWSPLRNPSPRPAPACGELRLGRLSPPRADTGGSSSGGCSGPDSKHR 319 +S H +P+PRP+ + L G L P D GS +GG G Sbjct: 2003 LLPASEHKV----------SPAPRPS-SLPILPSGPLYPGLFDIRGSPTGGAGGSADPFA 2051 Query: 320 TLPAPPAPTAWPAAGAPGAPNPAESRRGP 348 + PP P + G GA + A P Sbjct: 2052 PVFVPPHPGI--SGGLGGALSGASRSLSP 2078 Score = 30.0 bits (66), Expect = 4.0 Identities = 17/60 (28%), Positives = 28/60 (46%), Gaps = 2/60 (3%) Query: 305 GSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAESRRGPGPAQG--PPSRRDEPR 362 G++S G GP S + P APT ++G + + R P++G P + +PR Sbjct: 455 GAASSGAPGPTSGSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPR 514 Score = 29.6 bits (65), Expect = 5.2 Identities = 28/100 (28%), Positives = 39/100 (39%), Gaps = 10/100 (10%) Query: 96 SAPGQKPQPARQAQLPRPVSGVRPPPRGRVGLSQAPGRPLGACARAKGIRLVNPSPPRPP 155 SAPG A + P P SG + + ++ L + + +G R +PS R P Sbjct: 452 SAPG-----AASSGAPGPTSGSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHP 506 Query: 156 EPI---PASAAVTSGLTARGP--NTSATPGPQKGRGSAER 190 E P +SG GP T + GP GS R Sbjct: 507 EDAKRQPRGRPSSSGTPREGPAGGTGGSGGPGGSLGSRGR 546 >gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 855 Score = 60.5 bits (145), Expect = 3e-09 Identities = 94/364 (25%), Positives = 130/364 (35%), Gaps = 87/364 (23%) Query: 41 ALRPPRLSRGKDLKPRCGRGPAHSPDPGEGCEAWR---------RLSADRW--------- 82 A RPP RG+ P P PG R R+SA+ Sbjct: 91 ASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEA 150 Query: 83 PRPASLSP---RAALASAPGQ-KPQPARQAQ-------LPRPVSGVRPPPRGRVGLSQAP 131 P+ ++LS R PG P AR+++ LPRP RP P ++ P Sbjct: 151 PKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPP-----TEGP 205 Query: 132 GRPLGACARAKGIRLVNPSPPRPPEPI-------PASAAVTSGLTA------RGPNTSAT 178 + + + + PSP P PAS +++S T GP+ T Sbjct: 206 RKSVSSASEHS---TTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGT 262 Query: 179 PGPQKGRGSAERTNHIPKDKQRVAAPP--PPERPRVPFC--RGSSGLSVPTPPEHAGGRR 234 P R A + PK Q + P PP + P SS L+ P+P Sbjct: 263 P-----RAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSP-------- 309 Query: 235 KKFTRTRPLPRTSSFLSEVPSTRPLCATSSSHSAPL--PFFWSPLRNPSPRPAPACGELR 292 +++ S+ P T P SSS + L P PL PSP P+ L Sbjct: 310 -----------SAALQSQAPPTLPATPHSSSLTCQLATPL---PLAPPSPSAPPSLQTLP 355 Query: 293 LGRLSPPRADTGGSSSGGCSGPDSKHRTLPAPP-APTAWPAAGAPGAPNPAESRRGPGPA 351 +PP T +S G + H LP+PP +P A P AP A + P P Sbjct: 356 SPPATPPSQAT---TSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPP 412 Query: 352 QGPP 355 PP Sbjct: 413 ASPP 416 Score = 59.3 bits (142), Expect = 6e-09 Identities = 102/374 (27%), Positives = 126/374 (33%), Gaps = 88/374 (23%) Query: 29 ALSQPTLRHSASALRPPRLSRGKDLKPRCGRGPAHSPDPGEGCEAWRRLSADRWPRPASL 88 +L PTL+ + S L P LS P +P P + A P P + Sbjct: 368 SLGSPTLQATHSFLPSPPLS------------PLATPPP-QAPPALALPPLQAPPSPPAS 414 Query: 89 SPRAALASAPGQKPQPARQAQLPRPVSGVRPPPRGRVGLSQAPGRPLGACARAKGIRLVN 148 P + LA+ Q P L P S PPP V QAP P Sbjct: 415 PPLSPLATPSPQAPNALAVHLLQAPFS---PPPSPPV---QAPFSPPA------------ 456 Query: 149 PSPPRPPEPIPASAAVTSGLTARGPNTSATPGPQKGRGSAERTNHIPKDKQRVAAPP--- 205 SPP P P S A S P P P + P+ +AAPP Sbjct: 457 -SPPVSPSATPPSQAPPS---LAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQL 512 Query: 206 ---PPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRTRPLPRTSSFLSEVPSTRPLCAT 262 PP+ P P ++P+PP G+ F+ + LP S + P P+ A Sbjct: 513 AKPPPQAP--PALATPPLQALPSPPASFPGQAP-FSPSASLPM-SPLATPPPQAPPVLAA 568 Query: 263 SSSHSAPLP----FFWSPLRNPSPRPAPACGELRL------GRLSPPRA---------DT 303 P P +P R P+P P + RL G PP D Sbjct: 569 PLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDL 628 Query: 304 GGSSS----------GGCSGPDSKHRTLPAPPA------PTAW------PAA--GAPGAP 339 G SS G SGP+ P P A P AW P A GAPGAP Sbjct: 629 AGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAP 688 Query: 340 NPAESRRGPGPAQG 353 P GPG A G Sbjct: 689 LPWPPATGPGSADG 702 Score = 55.1 bits (131), Expect = 1e-07 Identities = 94/363 (25%), Positives = 128/363 (35%), Gaps = 66/363 (18%) Query: 11 SEEGRPTTESRIRPRLAEALSQPTLRHSASALRPPRLSRG-KDLKPRCG---RGPAHSPD 66 S R +R PR SQP + ALRPP+++ KD P G P +P Sbjct: 250 SSPARSGPSARGTPRAPAHPSQPKPK-GLQALRPPQVTPPRKDAAPALGPLSSSPLATPS 308 Query: 67 PGEGCEAWRRLSADRWPRPASLSPRAA--LASAPGQKPQPARQAQLPRPVSGVRPPPRGR 124 P ++ + P +SL+ + A L AP P LP P + PP + Sbjct: 309 PSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPA--TPPSQAT 366 Query: 125 VGL---------SQAPGRPLGACARAKGIRLVNPSPPRPPE-PIPASAAVTSGLTARGPN 174 L S P PL L P P PP +P A S + + Sbjct: 367 TSLGSPTLQATHSFLPSPPLSP--------LATPPPQAPPALALPPLQAPPSPPASPPLS 418 Query: 175 TSATPGPQKGRGSAERTNHIPKDKQRVAAPPPPERPRVPFCRGSSGLSVP--TPPEHAGG 232 ATP PQ A P +PPP + PF +S P TPP A Sbjct: 419 PLATPSPQAPNALAVHLLQAP------FSPPPSPPVQAPFSPPASPPVSPSATPPSQAP- 471 Query: 233 RRKKFTRTRPLPRTSSFLSEVPSTRPLCATSSSHSAPLPFFWSPLRNPSPRPAPACGELR 292 P ++ +VP + P S + P P + P P AP L+ Sbjct: 472 -----------PSLAAPPLQVPPSPPASPPMSPSATPPP------QAPPPLAAPP---LQ 511 Query: 293 LGRLSPPRADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAESRRGPGPAQ 352 L + PP+A ++ + LP+PPA A +P A P P P Q Sbjct: 512 LAK-PPPQAPPALATP--------PLQALPSPPASFPGQAPFSPSASLPMSPLATP-PPQ 561 Query: 353 GPP 355 PP Sbjct: 562 APP 564 Score = 53.1 bits (126), Expect = 4e-07 Identities = 84/319 (26%), Positives = 112/319 (35%), Gaps = 41/319 (12%) Query: 83 PRPASLSPRAALASAPGQ---KPQPARQAQLPRPVSGVRPPPRGRVGLSQAP-GRPL--G 136 PRP + PR +++SA +P PA + + P G++ P + S P P G Sbjct: 198 PRPPTEGPRKSVSSASEHSTTEPSPAARRR-PSAGGGLQRPASRSLSSSATPLSSPARSG 256 Query: 137 ACARAKGIRLVNPSPP--------RPPEPIPASAAVTSGLTARGPNTSATPGPQKGRGSA 188 AR +PS P RPP+ P L + ATP P S Sbjct: 257 PSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQ 316 Query: 189 E-----RTNHIPKDKQRVAAPPP--PERPRVPFCRGSSGLSVPTPPEHA----GGRRKKF 237 T H ++A P P P P P + TPP A G + Sbjct: 317 APPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQA 376 Query: 238 TRT-RPLPRTSSFLSEVPSTRPLCATSSSHSAPLPFF---WSPLRNPSPRP--APACGEL 291 T + P P S + P P A + P P SPL PSP+ A A L Sbjct: 377 THSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLL 436 Query: 292 RLGRLSPPRADTGGSSSGGCSGPDSKHRTLP--APPAPTA-------WPAAGAPGAPNPA 342 + PP S S P S T P APP+ A P A P +P+ Sbjct: 437 QAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSAT 496 Query: 343 ESRRGPGPAQGPPSRRDEP 361 + P P PP + +P Sbjct: 497 PPPQAPPPLAAPPLQLAKP 515 Score = 48.5 bits (114), Expect = 1e-05 Identities = 84/351 (23%), Positives = 115/351 (32%), Gaps = 43/351 (12%) Query: 16 PTTESRIRPRLAEALSQPTLRHSASALRP-PRLSRGKDLKPRCGRGPAHSPDPG-EGCEA 73 P+ +R RP L +P R +S+ P +R R PAH P +G +A Sbjct: 220 PSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQA 279 Query: 74 WRRLSADRWPRPASLSPRAALASAPGQKPQPARQAQLPRPVSGVRPPPRGRVGLSQAPGR 133 R PR + L+S+P P P+ Q P + L P Sbjct: 280 LRPPQVTP-PRKDAAPALGPLSSSPLATPSPSAALQSQAPPT-----------LPATPHS 327 Query: 134 PLGACARAKGIRLVNPSPPRPPE----PIPASAAVTSGLTARG-PNTSATPGPQKGRGSA 188 C A + L PSP PP P P + + T+ G P AT + Sbjct: 328 SSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLS 387 Query: 189 ERTNHIPKDKQRVAAPPPPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRTRPLPRTSS 248 P+ +A PP P P S L+ P+P A P S Sbjct: 388 PLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSP--QAPNALAVHLLQAPFSPPPS 445 Query: 249 FLSEVPSTRPLCATSSSHSAPLPFFWSPLRNPSPRPAPACGELRLGRLSPPRADTGGSSS 308 + P + P S + P P + P P+ A L++ PP S Sbjct: 446 PPVQAPFSPPASPPVSPSATP------PSQAP---PSLAAPPLQV----PPSPPASPPMS 492 Query: 309 GGCSGPDSKHRTLPAPPAPTAWPAAGAPGA---------PNPAESRRGPGP 350 + P L APP A P AP A P+P S G P Sbjct: 493 PSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAP 543 Score = 45.1 bits (105), Expect = 1e-04 Identities = 78/272 (28%), Positives = 98/272 (36%), Gaps = 63/272 (23%) Query: 136 GACARAKGIR---LVNPSPP---RPPEPI-PASAAVTSGLTARG---------------- 172 GA AR R L+ P PP RPP P+ PA+ V A G Sbjct: 11 GAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATI 70 Query: 173 PNTSATPGPQKGRGSAERTNHIPKDKQRVAAPPPPER-PRVPFCRGSSGLSVPTPPEHAG 231 P ++ GP + G++ R + PP R R P + +S V +P Sbjct: 71 PESAPRAGPTRSAGTSSR--------NPASRPPASGRGERAPPAKNTSPGPVSSP----- 117 Query: 232 GRRKKFTRTRPLPRTSSFLS-----------EVPSTRPLCA-TSSSHSAPLPFFWSPLRN 279 GR TR PL + +S E P L A S P P SP Sbjct: 118 GRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAM- 176 Query: 280 PSPRPAPACGELRLGRLSP---PRADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAP 336 + R A E+ L R +P PR T G S S+H T PA P+AG Sbjct: 177 -ARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSA--SEHSTTEPSPAARRRPSAGG- 232 Query: 337 GAPNPA----ESRRGP--GPAQGPPSRRDEPR 362 G PA S P PA+ PS R PR Sbjct: 233 GLQRPASRSLSSSATPLSSPARSGPSARGTPR 264 >gi|169160903 PREDICTED: hypothetical protein [Homo sapiens] Length = 426 Score = 60.5 bits (145), Expect = 3e-09 Identities = 92/303 (30%), Positives = 111/303 (36%), Gaps = 47/303 (15%) Query: 117 VRPPPRGRVGLSQAPGRPLGACARAKGIRLVNPSPPRPPEPIPA--SAAVTSGLTARGPN 174 V P P G + APG P A+ + P+P RPP AA +G T G Sbjct: 21 VAPQPEG----TDAPG-PAVCSPTARAPPPILPAPQRPPTRAREWEGAAWAAGATGVGAA 75 Query: 175 TSATPGPQKGRGSAERTNHIPKDKQRVAAPPPPERPRVPFCRGSSGLSVPTP-----PEH 229 A PG + R +P + + P P PR RGS G P P P Sbjct: 76 LLALPG-------SRRLGRVPLTFREASPGPAPGAPRA---RGSCGRE-PGPRRRRAPSS 124 Query: 230 AGGRRKKFTRTRPLPRTSSFLSEVPSTRPLCATSS-SHSAPLPFFWSPLR-----NPSPR 283 AG R R P PR S +P + C S S P R P P+ Sbjct: 125 AGKRPAAAARAAP-PRQRSLARCLPRSVGSCVRPSVGPSLPRRHCRRHCRCHCRRRPLPK 183 Query: 284 PAPACGELRLGRLSPPR--ADTGGSSSGGCSG-PDSKHRTLPAPPAPTAWPAAGAPGAPN 340 P P + RLG SPPR A GS + S P R PA G P Sbjct: 184 PPPL--QPRLGSASPPRLAAPLAGSRAPSLSPFPRRCRRRAERSPA--------GHGLPL 233 Query: 341 PAESRRGPGPAQGPPSRRDEPRRVVIAARECGREGSELPPSGEETPGR---RKSPSQSCK 397 P RG G G RR R V R+ GS P+G PGR R++ Q K Sbjct: 234 PRSLSRG-GEVVGARRRRGGEERRVRGRRQGCALGSPPIPAGPAAPGRAGERRAARQWRK 292 Query: 398 KGG 400 +GG Sbjct: 293 RGG 295 Score = 36.2 bits (82), Expect = 0.056 Identities = 69/295 (23%), Positives = 96/295 (32%), Gaps = 74/295 (25%) Query: 83 PRPASLSPRA--ALASAPGQKPQPARQAQLPRPVSGVRPPPRGRVGLSQAPGRPLGACAR 140 P PA +PRA + PG + + A + RP + R P + L++ R +G+C R Sbjct: 97 PGPAPGAPRARGSCGREPGPRRRRAPSSAGKRPAAAARAAPPRQRSLARCLPRSVGSCVR 156 Query: 141 AKGIRLVNPSPPR-----------PPEPIPASAAVTSGLTARGPNTSATPGPQKGRGSAE 189 V PS PR P+P + L + P A P Sbjct: 157 PS----VGPSLPRRHCRRHCRCHCRRRPLPKPPPLQPRLGSASPPRLAAP---------- 202 Query: 190 RTNHIPKDKQRVAAPPPPERPRVPFCRGSSGLSVPTP------PEHAGGRRKKFTRTRPL 243 + + P P R R R +G +P P E G RR++ R Sbjct: 203 -----LAGSRAPSLSPFPRRCRRRAERSPAGHGLPLPRSLSRGGEVVGARRRRGGEER-- 255 Query: 244 PRTSSFLSEVPSTRPLCATSSSHSAPLPFFWSPLRNPSPRPAPACGELRLGR-------- 295 V R CA S P+P P GE R R Sbjct: 256 --------RVRGRRQGCALG---SPPIP--------AGPAAPGRAGERRAARQWRKRGGG 296 Query: 296 --LSPPRADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAESRRGP 348 +SP G GG + P ++ + P+P W GAP A GP Sbjct: 297 PGVSPREGAQGEGVRGGVT-PRARGSSTCLRPSPATWQG----GAPYRAIFAAGP 346 Score = 28.9 bits (63), Expect = 9.0 Identities = 25/78 (32%), Positives = 28/78 (35%), Gaps = 7/78 (8%) Query: 318 HRTLPAPPAPTAWPAAGAPGAPNPA---ESRRGPGP----AQGPPSRRDEPRRVVIAARE 370 H PAP P P AP PA + R P P Q PP+R E AA Sbjct: 10 HPRTPAPGCPEVAPQPEGTDAPGPAVCSPTARAPPPILPAPQRPPTRAREWEGAAWAAGA 69 Query: 371 CGREGSELPPSGEETPGR 388 G + L G GR Sbjct: 70 TGVGAALLALPGSRRLGR 87 >gi|48375167 microtubule-associated protein 6 isoform 2 [Homo sapiens] Length = 439 Score = 60.1 bits (144), Expect = 4e-09 Identities = 76/290 (26%), Positives = 101/290 (34%), Gaps = 33/290 (11%) Query: 74 WRRLSADRWPRPASLSPRAALASAPGQKPQPARQAQLPRPVSGVRPPPRGRVGLSQAPGR 133 W +L P + + PG PQP Q +P + PP V + P + Sbjct: 16 WNQLDKADIAVPLVFTKYSEATEHPGAPPQPPPPQQQAQPA--LAPPSARAVAIETQPAQ 73 Query: 134 -PLGACARAKGIRLVNPSPPRPPEPIPASAAVTSGLTARGPNTSATPGPQKGRGSAER-T 191 L A ARA G P+P E PA+ SG PGP G GS Sbjct: 74 GELDAVARATG-----PAPGPTGEREPAAGPGRSG-----------PGPGLGSGSTSGPA 117 Query: 192 NHIPKDKQRVAAPPPPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRTRPLPRTSSFLS 251 + + + R PE P CR S P + +K R PLPR Sbjct: 118 DSVMRQDYRAWKVQRPE----PSCRPRSEYQPSDAPFERETQYQKDFRAWPLPRRGDH-- 171 Query: 252 EVPSTRPLCATSSSHSAPLPFFWSPLRNPSPR---PAPACGELRLGRLSPPRADTGGSSS 308 P S++ A P +P R P + P A E R +P A GG ++ Sbjct: 172 --PWIPKPVQISAASQASAPILGAPKRRPQSQERWPVQAAAEAREQEAAPGGA--GGLAA 227 Query: 309 GGCSGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAESRRGPGPAQGPPSRR 358 G SG D + A PA A G P + + A GP + R Sbjct: 228 GKASGADERDTRRKAGPAWIVRRAEGLGHEQTPLPAAQAQVQATGPEAGR 277 >gi|48375173 microtubule-associated protein 6 isoform 1 [Homo sapiens] Length = 813 Score = 60.1 bits (144), Expect = 4e-09 Identities = 76/290 (26%), Positives = 101/290 (34%), Gaps = 33/290 (11%) Query: 74 WRRLSADRWPRPASLSPRAALASAPGQKPQPARQAQLPRPVSGVRPPPRGRVGLSQAPGR 133 W +L P + + PG PQP Q +P + PP V + P + Sbjct: 16 WNQLDKADIAVPLVFTKYSEATEHPGAPPQPPPPQQQAQPA--LAPPSARAVAIETQPAQ 73 Query: 134 -PLGACARAKGIRLVNPSPPRPPEPIPASAAVTSGLTARGPNTSATPGPQKGRGSAER-T 191 L A ARA G P+P E PA+ SG PGP G GS Sbjct: 74 GELDAVARATG-----PAPGPTGEREPAAGPGRSG-----------PGPGLGSGSTSGPA 117 Query: 192 NHIPKDKQRVAAPPPPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRTRPLPRTSSFLS 251 + + + R PE P CR S P + +K R PLPR Sbjct: 118 DSVMRQDYRAWKVQRPE----PSCRPRSEYQPSDAPFERETQYQKDFRAWPLPRRGDH-- 171 Query: 252 EVPSTRPLCATSSSHSAPLPFFWSPLRNPSPR---PAPACGELRLGRLSPPRADTGGSSS 308 P S++ A P +P R P + P A E R +P A GG ++ Sbjct: 172 --PWIPKPVQISAASQASAPILGAPKRRPQSQERWPVQAAAEAREQEAAPGGA--GGLAA 227 Query: 309 GGCSGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAESRRGPGPAQGPPSRR 358 G SG D + A PA A G P + + A GP + R Sbjct: 228 GKASGADERDTRRKAGPAWIVRRAEGLGHEQTPLPAAQAQVQATGPEAGR 277 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 59.7 bits (143), Expect = 5e-09 Identities = 86/305 (28%), Positives = 113/305 (37%), Gaps = 46/305 (15%) Query: 85 PASLSPRAALASAPGQKPQPARQAQLPRPVSGVRPPPRGRVGLSQAPGRPLGACARAKGI 144 PAS P AS G++ PA+ P PVS GR + PG PLG KG+ Sbjct: 90 PASRPP----ASGRGERAPPAKNTS-PGPVSSP-----GRASGTTRPG-PLGQ----KGL 134 Query: 145 RLVNPSPPRPPEPI--PASAAVTSGLT--ARGPNTSATPGPQKGRGSAERTNHI--PKDK 198 R+ + P +A+++G GP T TP P R S + P+ Sbjct: 135 RISAEETVARGKATEAPKRSALSAGARRDTSGP-TPGTPSPAMARRSRAAGTEVGLPRPA 193 Query: 199 QRVAAPPPPERPRVPFCRGSS-GLSVPTP-----PEHAGGRRKKFTRTRPLPRT--SSFL 250 PP E PR S + P+P P GG ++ +R+ T SS Sbjct: 194 PSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPA 253 Query: 251 SEVPSTRPLCATSSSHSAPLPFFWSPLRNPSPRP-----APACGELRLGRLSPPRADTGG 305 PS R + S P P LR P P APA G L L+ P G Sbjct: 254 RSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATP--SPSG 311 Query: 306 SSSGGCSGPDSKHRTLPAP---------PAPTAWPAAGAPGAPNPAESRRGPGPAQGPPS 356 + + PD+ LPA P P A P+ AP + S P+Q PPS Sbjct: 312 TKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPS 371 Query: 357 RRDEP 361 P Sbjct: 372 MTTPP 376 Score = 54.7 bits (130), Expect = 2e-07 Identities = 107/404 (26%), Positives = 136/404 (33%), Gaps = 79/404 (19%) Query: 16 PTTESRIR---PRLAEALSQPTLRHSASALRPPRLSRGKDLKPRCGRGPAHSPDPGEGCE 72 P T S I P+ AL+ P L+ S P + P P +P Sbjct: 581 PETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASP 640 Query: 73 AWRRLSADRWPRPASLSPRAALASAPGQKPQPARQAQLP------RPVSGVRPPPRGRVG 126 L+ P +L+ L AP P P+ Q P PVS PP Sbjct: 641 PLSPLATPSPQAPNALAVH--LLQAPFSPP-PSPPVQAPFSPPASPPVSPSATPP----- 692 Query: 127 LSQAP----GRPLGACARAKGIRLVNPSPPRPPEPIPASAAVTSGLTARGP-----NTSA 177 SQAP PL ++PS PP+ P AA + P + SA Sbjct: 693 -SQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSA 751 Query: 178 TPGPQKGRGSAERTNHIPKDK-----QRVAAPPPPERPRVPFCRGSSGLSVPTPPEHAGG 232 TP P+ A +P A PPP+ P P ++P+PP G Sbjct: 752 TPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAP--PALATPPLQALPSPPASFPG 809 Query: 233 RRKKFTRTRPLPRTSSFLSEVPSTRPLCATSSSHSAPLP----FFWSPLRNPSPRPAPAC 288 + F+ + LP S + P P+ A P P +P R P+P P + Sbjct: 810 QAP-FSPSASLPM-SPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSV 867 Query: 289 GELRL------GRLSPPRA---------DTGGSSS----------GGCSGPDSKHRTLPA 323 RL G PP D G SS G SGP+ P Sbjct: 868 SGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPP 927 Query: 324 PPA------PTAW------PAA--GAPGAPNPAESRRGPGPAQG 353 P A P AW P A GAPGAP P GPG A G Sbjct: 928 PDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADG 971 Score = 54.3 bits (129), Expect = 2e-07 Identities = 86/347 (24%), Positives = 127/347 (36%), Gaps = 77/347 (22%) Query: 41 ALRPPRLSRGKDLKP--RCGRGPAHSPD-------PGEGCEAWRRLSADRW--------- 82 A RPP RG+ P GP SP PG + R+SA+ Sbjct: 91 ASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEA 150 Query: 83 PRPASLSP---RAALASAPG-QKPQPARQAQ-------LPRPVSGVRPPPRGRVGLSQAP 131 P+ ++LS R PG P AR+++ LPRP RP P ++ P Sbjct: 151 PKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPP-----TEGP 205 Query: 132 GRPLGACARAKGIRLVNPSPPRPPEPI-------PASAAVTSGLT------ARGPNTSAT 178 + + + + PSP P PAS +++S T GP+ T Sbjct: 206 RKSVSSASEHS---TTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGT 262 Query: 179 PGPQKGRGSAERTNHIPKDKQRVAAP--PPPERPRVPFC--RGSSGLSVPTPPEHAGGRR 234 P R A + PK Q + P PP + P SS L+ P+P Sbjct: 263 P-----RAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSP-------- 309 Query: 235 KKFTRTRPLPRTSSFLSEVPSTRPLCATSSSHSAPLPFFWSPLRNPSPRPAPACGELRLG 294 T+ RP+P + + +P+T P S + PL PL PSP P+ L Sbjct: 310 -SGTKARPVPPPDNAATPLPATLP---PSPPLATPL-----PLAPPSPSAPPSLQTLPSP 360 Query: 295 RLSPPRADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAPGAPNP 341 +PP ++ P S +T+P P + + P+P Sbjct: 361 PATPPSQAPPSMTTPPMQAPPSL-QTIPPIQVPHSLTSPSLQAPPSP 406 Score = 48.5 bits (114), Expect = 1e-05 Identities = 109/427 (25%), Positives = 151/427 (35%), Gaps = 87/427 (20%) Query: 11 SEEGRPTTESRIRPRLAEALSQPTLRHSASALRPPRLSRG-KDLKPRCG---RGPAHSPD 66 S R +R PR SQP + ALRPP+++ KD P G P +P Sbjct: 250 SSPARSGPSARGTPRAPAHPSQPKPK-GLQALRPPQVTPPRKDAAPALGPLSSSPLATPS 308 Query: 67 PGEGCEAWRRLSADR--WPRPASLSPRAALAS----APGQKPQPARQAQLPRPVSGVRPP 120 P G +A D P PA+L P LA+ AP P LP P + PP Sbjct: 309 PS-GTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPA--TPP 365 Query: 121 PRGRVGLSQAPGRPLGACARAKGIR----LVNPSPPRPPEPIPASA--AVTS--GLTARG 172 + ++ P + + I+ L +PS PP P+ S+ A TS T + Sbjct: 366 SQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQA 425 Query: 173 PNTSATPGPQKGRGSA---ERTNHIPKDKQRVAAP------PP----------------- 206 ++ T P++ + S R P D + AP PP Sbjct: 426 THSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLT 485 Query: 207 --------------PERPR----VPFCRGSSGLSVP----------TPP-EHAGGRRKKF 237 P+ P +P S L+ P TPP E+ Sbjct: 486 IHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPP 545 Query: 238 TRTRPLPRTSSFLSE--VPSTRPLCATSSSHSAPLPFFWSPLRNPSPRPAPACGELRL-G 294 +T P T+ L P+ PL A S + P P S + P P+ PA L G Sbjct: 546 LQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQG 605 Query: 295 RLSPPRADTGGSSSGGCSGPDSKHRTLPAPPAPTAWP-----AAGAPGAPNPAESRRGPG 349 SPP + ++ + P L APP+P A P A +P APN Sbjct: 606 LPSPPLSPL--ATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQA 663 Query: 350 PAQGPPS 356 P PPS Sbjct: 664 PFSPPPS 670 Score = 47.4 bits (111), Expect = 2e-05 Identities = 88/355 (24%), Positives = 120/355 (33%), Gaps = 50/355 (14%) Query: 16 PTTESRIRPRLAEALSQPTLRHSASALRP-PRLSRGKDLKPRCGRGPAHSPDPG-EGCEA 73 P+ +R RP L +P R +S+ P +R R PAH P +G +A Sbjct: 220 PSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQA 279 Query: 74 WRRLSADRWPRPASLSPRAALASAPGQKPQPA--RQAQLPRPVSGVRPPPRGRVGLSQAP 131 R PR + L+S+P P P+ + +P P + P P + P Sbjct: 280 LRPPQVTP-PRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPA-----TLPP 333 Query: 132 GRPLGACARAKGIRLVNPSPPRPPEPIPASAAVTSGLTARGPNTSATPGPQKGRGSAERT 191 PL A + L PSP PP P+ ATP Q Sbjct: 334 SPPL-----ATPLPLAPPSPSAPPS------------LQTLPSPPATPPSQAPPSMTTPP 376 Query: 192 NHIPKDKQRVAAPPPPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRTRP-LPRTSSFL 250 P Q + PP + VP S L P P + + P L T SFL Sbjct: 377 MQAPPSLQTI---PPIQ---VPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFL 430 Query: 251 SEVPSTRPLCATSSSHSAPLPFFWSPLRNPSPRPAPACGELRLGRLSPPRADTGGSSSGG 310 + P TS S A P PL+ P PA SPP + + Sbjct: 431 TMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPA-----------SPPLQTSLSPAVSP 479 Query: 311 CSGPDSKH----RTLPAPPAPTAWPAAGAPGAPNPAESRRGPGPAQGPPSRRDEP 361 S P + H + A +P A P + P +S P Q PP+ P Sbjct: 480 LSSPLTIHPLQALSSLASHSPQA-PLSSLIMPPLETQSSLAPPSLQTPPASLTTP 533 Score = 45.1 bits (105), Expect = 1e-04 Identities = 78/272 (28%), Positives = 98/272 (36%), Gaps = 63/272 (23%) Query: 136 GACARAKGIR---LVNPSPP---RPPEPI-PASAAVTSGLTARG---------------- 172 GA AR R L+ P PP RPP P+ PA+ V A G Sbjct: 11 GAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATI 70 Query: 173 PNTSATPGPQKGRGSAERTNHIPKDKQRVAAPPPPER-PRVPFCRGSSGLSVPTPPEHAG 231 P ++ GP + G++ R + PP R R P + +S V +P Sbjct: 71 PESAPRAGPTRSAGTSSR--------NPASRPPASGRGERAPPAKNTSPGPVSSP----- 117 Query: 232 GRRKKFTRTRPLPRTSSFLS-----------EVPSTRPLCA-TSSSHSAPLPFFWSPLRN 279 GR TR PL + +S E P L A S P P SP Sbjct: 118 GRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAM- 176 Query: 280 PSPRPAPACGELRLGRLSP---PRADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAP 336 + R A E+ L R +P PR T G S S+H T PA P+AG Sbjct: 177 -ARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSA--SEHSTTEPSPAARRRPSAGG- 232 Query: 337 GAPNPA----ESRRGP--GPAQGPPSRRDEPR 362 G PA S P PA+ PS R PR Sbjct: 233 GLQRPASRSLSSSATPLSSPARSGPSARGTPR 264 >gi|110832843 TBP-associated factor 4 [Homo sapiens] Length = 1085 Score = 59.7 bits (143), Expect = 5e-09 Identities = 89/327 (27%), Positives = 113/327 (34%), Gaps = 60/327 (18%) Query: 58 GRGPAHSPDPGEGCEAWRRLSADRWPRPASLSPRAALASAPGQKPQPARQAQLPRPVSGV 117 G GPA +P G A A R RP P+ +P + PA A P + + Sbjct: 72 GAGPA-APAEGAPGAAPEPPPAGR-ARPGGGGPQRPGPPSPRRPLVPAGPAP---PAAKL 126 Query: 118 RPPPRGRVGLSQAPGRPLGACARAKGIRLVNPSPPRPPEPIPASAAVTSGLTARGPNTSA 177 RPPP G G S AP A A P+ P P + A A G GP Sbjct: 127 RPPPEGSAG-SCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPG-PGPGPGPGP 184 Query: 178 TPGPQKGRGSAERTNHIPK--DKQRVAAPPPPERPRVPFCRGSSGLSVPTPPEHAGGRRK 235 PG G G+A+ N + AAP V +P P A G Sbjct: 185 GPGKPAGPGAAQTLNGSAALLNSHHAAAPA------VSLVNNGPAALLPLPKPAAPGT-- 236 Query: 236 KFTRTRPLPRTSSFLSEVPSTRPLCATSSSHSAPLPFFWSPLRNPSPRPAPACGELRLGR 295 + +T F+ P + + AP +P P P PAPA G Sbjct: 237 -------VIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAP---PPPPPAPATLARPPGH 286 Query: 296 ----------LSPPRADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAP----GAPNP 341 + PP A G S+G A PAP PAAG P G P P Sbjct: 287 PAGPPTAAPAVPPPAAAQNGGSAG-------------AAPAPA--PAAGGPAGVSGQPGP 331 Query: 342 AESRRGPGPAQGPPSRRDEPRRVVIAA 368 + P P + + P+RVV AA Sbjct: 332 GAAAAAPAPG----VKAESPKRVVQAA 354 Score = 55.8 bits (133), Expect = 7e-08 Identities = 75/296 (25%), Positives = 94/296 (31%), Gaps = 68/296 (22%) Query: 86 ASLSPRAALASAPGQKPQP-----ARQA----QLPRPVSGVRP-------PPRGRVGLSQ 129 A P A APG P+P AR Q P P S RP PP + L Sbjct: 71 AGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAK--LRP 128 Query: 130 APGRPLGACARAKGIRLVNPSPPRPPEPIPASAAVTSGLTARGPNTSATPGPQKGRGSAE 189 P G+CA V P EP PA A +G A PGP G G Sbjct: 129 PPEGSAGSCAPVPAAAAVAAGP----EPAPAGPAKPAGPAALAARAGPGPGPGPGPGPG- 183 Query: 190 RTNHIPKDKQRVAAPPPPERPRVPFCRGS-SGLSVPTPPEHAGGRRKKFTRTRPLPRTSS 248 P P +P P + +G + HA P Sbjct: 184 ---------------PGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPA----- 223 Query: 249 FLSEVPSTRPLCATSSSHSAPLPFFWSPLRNPSPRPAPACGELRLGRLSPPRADTGGSSS 308 + +P +P + + P +P PAPA SPP A + + Sbjct: 224 --ALLPLPKPAAPGTVIQTPPFVGAAAP-------PAPAAP-------SPPAAPAPAAPA 267 Query: 309 GGCSGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAESRRG--------PGPAQGPPS 356 P TL PP A P AP P PA ++ G P PA G P+ Sbjct: 268 AAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPA 323 Score = 50.1 bits (118), Expect = 4e-06 Identities = 73/280 (26%), Positives = 88/280 (31%), Gaps = 40/280 (14%) Query: 85 PASLSPRAALASAPGQKPQPARQAQLPRPVSGVRPPPRGRVGLSQAPGRPLGACARAKGI 144 P + RAA A A G P +G P AP P AR G Sbjct: 45 PRTPEVRAAAAGALGNHVVSGS----PAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGG 100 Query: 145 RLVNPSPPRPPEP-IPASAAVTSGLTARGPNTSATPGPQKGRGSAERTNHIPKDKQRVAA 203 P PP P P +PA A P P P+ GSA +P A Sbjct: 101 GPQRPGPPSPRRPLVPAGPAP--------PAAKLRPPPE---GSAGSCAPVPAAAAVAAG 149 Query: 204 PPP----PERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRTRPLPRTSSFLSEVPSTRPL 259 P P P +P P + P P G P P + + Sbjct: 150 PEPAPAGPAKPAGPAALAARAGPGPGPGPGPG--------PGPGPGKPAGPGAAQTLNGS 201 Query: 260 CATSSSHSAPLPFFWSPLRNPS---PRPAPACGELRLGRLSPPRADTGGSSSGGCSGPDS 316 A +SH A P P+ P P PA + +PP + P Sbjct: 202 AALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQ--TPPFVGAAAPPAPAAPSP-- 257 Query: 317 KHRTLPAPPAPTAWPAAGAPGAPNPAESRRGPGPAQGPPS 356 PA PAP A AA P P PA R PG GPP+ Sbjct: 258 -----PAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPT 292 Score = 42.7 bits (99), Expect = 6e-04 Identities = 80/320 (25%), Positives = 108/320 (33%), Gaps = 49/320 (15%) Query: 53 LKPRCGRGPAHSPDPGEGCEAWRRL---SADRWPRPASL--SPRAALASAPGQKPQPARQ 107 L R G GP P PG G + +A A+L S AA + PA Sbjct: 166 LAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAAL 225 Query: 108 AQLPRPVSG---VRPPPRGRVGLSQAPGRPLGACARAKGIRLVNPSPPRPPEPIPASAAV 164 LP+P + ++ PP AP P A A + P PP P PA+ A Sbjct: 226 LPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPA---APAAAPPPPPPAPATLAR 282 Query: 165 TSGLTARGPNTSA----TPGPQKGRGSAERTNHIPKDKQRVAAPPPPERPRVPFCRGSSG 220 G A GP T+A P + GSA AAP P P G +G Sbjct: 283 PPGHPA-GPPTAAPAVPPPAAAQNGGSAG------------AAPAP-----APAAGGPAG 324 Query: 221 LSVPTPPEHAGGRRKKFTRTRPLPRTSSFLSEVPSTRPLCATSSSHSAPLPFFWSPLRNP 280 +S P A + R + P+ + L A+ + +A ++ Sbjct: 325 VSGQPGPGAAAAAPAPGVKAESPKRVVQ--AAPPAAQTLAASGPASTAASMVIGPTMQGA 382 Query: 281 SPRPAPACGELRLGRLSPPRADTGGSSSGGCSG--PDSKHRTLPAPPA---PTAWPAAGA 335 P PA + PP T G +G S RT A + T P A Sbjct: 383 LPSPA---------AVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLA 433 Query: 336 PGAPNPAESRRGPGPAQGPP 355 P P P ++ Q PP Sbjct: 434 PRLPQPPQNPTNIQNFQLPP 453 Score = 37.4 bits (85), Expect = 0.025 Identities = 47/161 (29%), Positives = 57/161 (35%), Gaps = 23/161 (14%) Query: 251 SEVPSTRPLCATSSSHSAPLPFFWSPLRNPSPRPAPACGELRLGRLSPPRADTGGSSSGG 310 + V S P A + +AP +P P P PA G R G P R Sbjct: 60 NHVVSGSPAGAAGAGPAAPAE--GAPGAAPEPPPA---GRARPGGGGPQRP--------- 105 Query: 311 CSGPDSKHRTL-PAPPAPTAW----PAAGAPG--APNPAESRRGPGPAQGPPSRRDEPRR 363 GP S R L PA PAP A P G+ G AP PA + GP P Sbjct: 106 --GPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGP 163 Query: 364 VVIAARECGREGSELPPSGEETPGRRKSPSQSCKKGGESIL 404 +AAR G P PG+ P + G + L Sbjct: 164 AALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAAL 204 Score = 33.9 bits (76), Expect = 0.28 Identities = 48/171 (28%), Positives = 60/171 (35%), Gaps = 24/171 (14%) Query: 15 RPTTESRIRPRLAEALSQPTLRH---SASALRPPRLSRGKDLKPRCGRGP---AHSPDPG 68 RP P A A+ P SA A P + G GP A +P PG Sbjct: 282 RPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPG 341 Query: 69 EGCEAWRRLSADRWPRPASLSPRAALASAPGQKPQPARQAQLPRPVSGVRPPPRGRVGLS 128 E+ +R+ P +L+ ++A P Q LP P + PPP Sbjct: 342 VKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAA--VPPP------- 392 Query: 129 QAPGRPLGACARAKGIRLVNPSPPRPPEPIPASAAVTSGLTARGPNTSATP 179 APG P G A G V S R P A TSG+ A T P Sbjct: 393 -APGTPTGLPKGAAG--AVTQSLSRTP------TATTSGIRATLTPTVLAP 434 Score = 31.2 bits (69), Expect = 1.8 Identities = 30/91 (32%), Positives = 38/91 (41%), Gaps = 10/91 (10%) Query: 296 LSPPRADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAPGA---PNPAESRR--GPGP 350 L+P + +++G A A A PA GAPGA P PA R G GP Sbjct: 43 LAPRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGP 102 Query: 351 AQ-GPPSRRDEPRRVVIAARECGREGSELPP 380 + GPPS PRR ++ A PP Sbjct: 103 QRPGPPS----PRRPLVPAGPAPPAAKLRPP 129 >gi|160707881 formin 2 [Homo sapiens] Length = 1722 Score = 59.3 bits (142), Expect = 6e-09 Identities = 106/387 (27%), Positives = 123/387 (31%), Gaps = 63/387 (16%) Query: 33 PTLRHSASALRPPRLSRGKDLKPRC-GRG-PAHSPDPGEGCEAWRRLSADRWPRPASLSP 90 P L +A PP G L P G G P P PG G L P P L P Sbjct: 946 PPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL-P 1004 Query: 91 RAALASAPGQKPQPARQAQLPRPVSGVR-PPPRGRVGLSQAPGRPLGACARAKGIRLVNP 149 A + P P P P P+ G PPP G P PL + P Sbjct: 1005 GAGIPPPP---PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG-------IPP 1054 Query: 150 SPPRPPEPIPASAAVT-SGLTARGPNTSA---TPGPQKGRGSAERTNHIPKDKQRVAAPP 205 PP P IP + +G+ P A P P G G P V PP Sbjct: 1055 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP-----PPPLPGVGIPP 1109 Query: 206 PPERPR--VPFCRGSSGLSVPTPPEHAGGRRKKFTRTRPLPRTSSFLSEVPSTRPLCATS 263 PP P +P G +P PP G PLPR +P PL Sbjct: 1110 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAG---IPPPPPLPRVG-----IPPPPPLPGAG 1161 Query: 264 SSHSAPLPFFWSPLRNPSPRPAPACGELRLGRLSPPRADTGGSSSGGCSGPDSKHRTLPA 323 PLP P P P P G + PP G G P +P Sbjct: 1162 IPPPPPLP----GAGIPPPPPLPGVG------IPPPPPLPG---VGIPPPPPLPGAGIPP 1208 Query: 324 PPAPTAWPAAGAPGAPNPAESRRGPG-------PAQGPPSRRDEPRRVVIAARECGREGS 376 PP P G P AP P G G P GPP + + CG Sbjct: 1209 PPP---LPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPP 1265 Query: 377 ELPPSG------EETPGRRKSPSQSCK 397 L PSG + G RK P + C+ Sbjct: 1266 PL-PSGLFGLGMNQDKGSRKQPIEPCR 1291 Score = 44.3 bits (103), Expect = 2e-04 Identities = 67/259 (25%), Positives = 82/259 (31%), Gaps = 35/259 (13%) Query: 98 PGQKPQPARQAQLPRPVSGVRPPPRGRVGLSQAPGRPLGACARAKGIRLVNPSPPRPPEP 157 P P P ++ P G+ PPP + P P A + ++ PP PP P Sbjct: 856 PSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPP-PPPP 914 Query: 158 IPASAAVTSGLTARGPNTSATPGPQKGRGSAERTNHIPKDKQRVAAPPPPERP--RVPFC 215 +P A + G P P G G P A PPPP P +P Sbjct: 915 LP-GAGIPPPPPLPGAGILPLP-PLPGAGIPP-----PPPLPGAAIPPPPPLPGAGIPLP 967 Query: 216 RGSSGLSVPTPPEHAGGRRKKFTRTRPLPRTSSFLSEVPSTRPLCATSSSHSAPLPFFWS 275 G +P PP G PLP +P PL PLP Sbjct: 968 PPLPGAGIPPPPPLPGA---GIPPPPPLPGAG-----IPPPPPLPGAGIPPPPPLP---- 1015 Query: 276 PLRNPSPRPAPACGELRLGRLSPPRADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGA 335 P P P P G + PP G +G P +P PP P AG Sbjct: 1016 GAGIPPPPPLPGAG------IPPPPPLPG---AGIPPPPPLPGAGIPPPP---PLPGAGI 1063 Query: 336 PGAPN-PAESRRGPGPAQG 353 P P P P P G Sbjct: 1064 PPPPPLPGAGIPPPPPLPG 1082 >gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] Length = 1012 Score = 57.4 bits (137), Expect = 2e-08 Identities = 87/354 (24%), Positives = 118/354 (33%), Gaps = 51/354 (14%) Query: 29 ALSQPTLRHSASALRPPRLSRGKDLKPRCGRGPAHSPDPGEGCEAWRRLSADRWPR-PAS 87 AL PT A + PP G P G P+ + P +G + A P+ P + Sbjct: 186 ALQAPTGVTPAPSSAPP----GTPQLPTPGPTPSATAVPPQGSPTASQ--APNQPQAPTA 239 Query: 88 LSPRAALASAPGQKPQPARQAQLPRPVSGVRP--PPRGRVGLSQAPGR---------PLG 136 P + AP PQ P S P P G G AP P G Sbjct: 240 PVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPG 299 Query: 137 ACARAKGIRLVNPSPPRP----PEPIPASAAVTSGLTARGPNTSAT-PGPQKGRGSAERT 191 + G L +P PP+P P+ A + + A P+TS P Q S + Sbjct: 300 PHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPP 359 Query: 192 NHIPKDKQRVAAPPPPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRTRPLPRTSSFLS 251 P +A P P P + + + PP +G P P Sbjct: 360 REQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPP------- 412 Query: 252 EVPSTRPLCATSSSH---SAPLPFFWSPLRNPSPR-PAPACGELRLGRLSPPRADTGGSS 307 P+ +PL + S+ H + P P P P P PA G + L PP A Sbjct: 413 --PALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPAS----- 465 Query: 308 SGGCSGPDSKHRTLPAPP------APTAWPAAGAPGAPNPAESRRGPGPAQGPP 355 P H+ P PP P P P P+ + GPG + PP Sbjct: 466 ----HPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPP 515 Score = 40.4 bits (93), Expect = 0.003 Identities = 50/176 (28%), Positives = 68/176 (38%), Gaps = 40/176 (22%) Query: 83 PRPASLSPRAALAS--APGQKPQPAR---QAQLPRPVSGVRPPPRGRVGLSQAPGRPLGA 137 P P +L P ++L++ P P P + Q+Q P P S +PP GL+Q+ P Sbjct: 410 PPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQ-PLPSSPAQPP-----GLTQSQNLPPPP 463 Query: 138 CARAK-GIRLVNPSPPRP--------PEPIPASAAVTSGLTARGPNTSATP---GPQKGR 185 + G+ V P PP P PI ++ GP TSA P G Sbjct: 464 ASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASG 523 Query: 186 GSAERTNHIP-----------KDKQRVAAPPPPERPRVPFCRGSSGLSVPTPPEHA 230 GS + P D + +PPPP PR P S +V P HA Sbjct: 524 GSIAGGSSCPLPTVQIKEEALDDAEEPESPPPP--PRSP----SPEPTVVDTPSHA 573 Score = 30.8 bits (68), Expect = 2.4 Identities = 28/143 (19%), Positives = 51/143 (35%), Gaps = 5/143 (3%) Query: 218 SSGLSVPTPPEH-----AGGRRKKFTRTRPLPRTSSFLSEVPSTRPLCATSSSHSAPLPF 272 S+ S+P+P ++ + +++ P + + ++ PS+ P P P Sbjct: 156 STSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPS 215 Query: 273 FWSPLRNPSPRPAPACGELRLGRLSPPRADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPA 332 + SP + A + + P + + P S H P P P Sbjct: 216 ATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPL 275 Query: 333 AGAPGAPNPAESRRGPGPAQGPP 355 G+ G P+ + P QGPP Sbjct: 276 TGSAGQPSAPSHAQPPLHGQGPP 298 >gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] Length = 1566 Score = 57.4 bits (137), Expect = 2e-08 Identities = 87/354 (24%), Positives = 118/354 (33%), Gaps = 51/354 (14%) Query: 29 ALSQPTLRHSASALRPPRLSRGKDLKPRCGRGPAHSPDPGEGCEAWRRLSADRWPR-PAS 87 AL PT A + PP G P G P+ + P +G + A P+ P + Sbjct: 740 ALQAPTGVTPAPSSAPP----GTPQLPTPGPTPSATAVPPQGSPTASQ--APNQPQAPTA 793 Query: 88 LSPRAALASAPGQKPQPARQAQLPRPVSGVRP--PPRGRVGLSQAPGR---------PLG 136 P + AP PQ P S P P G G AP P G Sbjct: 794 PVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPG 853 Query: 137 ACARAKGIRLVNPSPPRP----PEPIPASAAVTSGLTARGPNTSAT-PGPQKGRGSAERT 191 + G L +P PP+P P+ A + + A P+TS P Q S + Sbjct: 854 PHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPP 913 Query: 192 NHIPKDKQRVAAPPPPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRTRPLPRTSSFLS 251 P +A P P P + + + PP +G P P Sbjct: 914 REQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPP------- 966 Query: 252 EVPSTRPLCATSSSH---SAPLPFFWSPLRNPSPR-PAPACGELRLGRLSPPRADTGGSS 307 P+ +PL + S+ H + P P P P P PA G + L PP A Sbjct: 967 --PALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPAS----- 1019 Query: 308 SGGCSGPDSKHRTLPAPP------APTAWPAAGAPGAPNPAESRRGPGPAQGPP 355 P H+ P PP P P P P+ + GPG + PP Sbjct: 1020 ----HPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPP 1069 Score = 40.4 bits (93), Expect = 0.003 Identities = 50/176 (28%), Positives = 68/176 (38%), Gaps = 40/176 (22%) Query: 83 PRPASLSPRAALAS--APGQKPQPAR---QAQLPRPVSGVRPPPRGRVGLSQAPGRPLGA 137 P P +L P ++L++ P P P + Q+Q P P S +PP GL+Q+ P Sbjct: 964 PPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQ-PLPSSPAQPP-----GLTQSQNLPPPP 1017 Query: 138 CARAK-GIRLVNPSPPRP--------PEPIPASAAVTSGLTARGPNTSATP---GPQKGR 185 + G+ V P PP P PI ++ GP TSA P G Sbjct: 1018 ASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASG 1077 Query: 186 GSAERTNHIP-----------KDKQRVAAPPPPERPRVPFCRGSSGLSVPTPPEHA 230 GS + P D + +PPPP PR P S +V P HA Sbjct: 1078 GSIAGGSSCPLPTVQIKEEALDDAEEPESPPPP--PRSP----SPEPTVVDTPSHA 1127 Score = 30.8 bits (68), Expect = 2.4 Identities = 28/143 (19%), Positives = 51/143 (35%), Gaps = 5/143 (3%) Query: 218 SSGLSVPTPPEH-----AGGRRKKFTRTRPLPRTSSFLSEVPSTRPLCATSSSHSAPLPF 272 S+ S+P+P ++ + +++ P + + ++ PS+ P P P Sbjct: 710 STSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPS 769 Query: 273 FWSPLRNPSPRPAPACGELRLGRLSPPRADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPA 332 + SP + A + + P + + P S H P P P Sbjct: 770 ATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPL 829 Query: 333 AGAPGAPNPAESRRGPGPAQGPP 355 G+ G P+ + P QGPP Sbjct: 830 TGSAGQPSAPSHAQPPLHGQGPP 852 >gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] Length = 1566 Score = 57.4 bits (137), Expect = 2e-08 Identities = 87/354 (24%), Positives = 118/354 (33%), Gaps = 51/354 (14%) Query: 29 ALSQPTLRHSASALRPPRLSRGKDLKPRCGRGPAHSPDPGEGCEAWRRLSADRWPR-PAS 87 AL PT A + PP G P G P+ + P +G + A P+ P + Sbjct: 740 ALQAPTGVTPAPSSAPP----GTPQLPTPGPTPSATAVPPQGSPTASQ--APNQPQAPTA 793 Query: 88 LSPRAALASAPGQKPQPARQAQLPRPVSGVRP--PPRGRVGLSQAPGR---------PLG 136 P + AP PQ P S P P G G AP P G Sbjct: 794 PVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPG 853 Query: 137 ACARAKGIRLVNPSPPRP----PEPIPASAAVTSGLTARGPNTSAT-PGPQKGRGSAERT 191 + G L +P PP+P P+ A + + A P+TS P Q S + Sbjct: 854 PHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPP 913 Query: 192 NHIPKDKQRVAAPPPPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRTRPLPRTSSFLS 251 P +A P P P + + + PP +G P P Sbjct: 914 REQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPP------- 966 Query: 252 EVPSTRPLCATSSSH---SAPLPFFWSPLRNPSPR-PAPACGELRLGRLSPPRADTGGSS 307 P+ +PL + S+ H + P P P P P PA G + L PP A Sbjct: 967 --PALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPAS----- 1019 Query: 308 SGGCSGPDSKHRTLPAPP------APTAWPAAGAPGAPNPAESRRGPGPAQGPP 355 P H+ P PP P P P P+ + GPG + PP Sbjct: 1020 ----HPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPP 1069 Score = 40.4 bits (93), Expect = 0.003 Identities = 50/176 (28%), Positives = 68/176 (38%), Gaps = 40/176 (22%) Query: 83 PRPASLSPRAALAS--APGQKPQPAR---QAQLPRPVSGVRPPPRGRVGLSQAPGRPLGA 137 P P +L P ++L++ P P P + Q+Q P P S +PP GL+Q+ P Sbjct: 964 PPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQ-PLPSSPAQPP-----GLTQSQNLPPPP 1017 Query: 138 CARAK-GIRLVNPSPPRP--------PEPIPASAAVTSGLTARGPNTSATP---GPQKGR 185 + G+ V P PP P PI ++ GP TSA P G Sbjct: 1018 ASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASG 1077 Query: 186 GSAERTNHIP-----------KDKQRVAAPPPPERPRVPFCRGSSGLSVPTPPEHA 230 GS + P D + +PPPP PR P S +V P HA Sbjct: 1078 GSIAGGSSCPLPTVQIKEEALDDAEEPESPPPP--PRSP----SPEPTVVDTPSHA 1127 Score = 30.8 bits (68), Expect = 2.4 Identities = 28/143 (19%), Positives = 51/143 (35%), Gaps = 5/143 (3%) Query: 218 SSGLSVPTPPEH-----AGGRRKKFTRTRPLPRTSSFLSEVPSTRPLCATSSSHSAPLPF 272 S+ S+P+P ++ + +++ P + + ++ PS+ P P P Sbjct: 710 STSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPS 769 Query: 273 FWSPLRNPSPRPAPACGELRLGRLSPPRADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPA 332 + SP + A + + P + + P S H P P P Sbjct: 770 ATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPL 829 Query: 333 AGAPGAPNPAESRRGPGPAQGPP 355 G+ G P+ + P QGPP Sbjct: 830 TGSAGQPSAPSHAQPPLHGQGPP 852 >gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo sapiens] Length = 309 Score = 57.4 bits (137), Expect = 2e-08 Identities = 88/325 (27%), Positives = 114/325 (35%), Gaps = 67/325 (20%) Query: 89 SPRAALASAPGQKPQPARQAQLPRPVSGV---RPPPRGRV--GLSQAPGRPLGACARAKG 143 SP G++PQ Q Q P G RPP G G PG+P G + G Sbjct: 28 SPSVISGKPEGRRPQGGNQPQRTPPPPGKPEGRPPQGGNQSQGPPPRPGKPEGPPPQG-G 86 Query: 144 IRLVNPSPPRPPEPIPASAAVTSGLTARGPNTSATPGPQKGRGSAERTNHIPKDKQRVAA 203 + P PPRP +P G +G N S P P+ G+ P+ + Sbjct: 87 NQSQGP-PPRPGKP--------EGQPPQGGNQSQGPPPRPGKPEGPP----PQGGNQSQG 133 Query: 204 PPP-PERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRTRPLPRTSSFLSEVPSTRPLCAT 262 PPP P +P P +G G PP G + P S+ P P Sbjct: 134 PPPRPGKPEGPPPQG--GNQSQGPPPRPG-------KPEGPPPQGGNQSQGPPPHP---- 180 Query: 263 SSSHSAPLPFFWSPLRNPSPRPAPACGELRLGRLSPPRADTGGSSSGGC-------SGPD 315 P P + + P PRP G PP+ GG+ S G GP Sbjct: 181 -GKPEGPPPQGGNQSQGPPPRPGKPEGP-------PPQ---GGNQSQGPPPRPGKPEGPP 229 Query: 316 SKHRTLPAPPAPTAWPAAGAPGAPNPAESRRG-----PGPAQGPPSRRDEPRRVVIAARE 370 S+ P P P G P P P E + PG QGPP P++ + Sbjct: 230 SQGGNKPQGPPPHP----GKPQGPPPQEGNKPQRPPPPGRPQGPPPPGGNPQQPL--PPP 283 Query: 371 CGR-EGSELPPSGEETPGRRKSPSQ 394 G+ +G PP G GR P Q Sbjct: 284 AGKPQGPPPPPQG----GRPHRPPQ 304 Score = 55.5 bits (132), Expect = 9e-08 Identities = 74/275 (26%), Positives = 96/275 (34%), Gaps = 44/275 (16%) Query: 99 GQKPQPARQAQ--LPRPVSGVRPPPRG---RVGLSQAPGRPLGACARAKGIRLVNPSPPR 153 G+ PQ Q+Q PRP PPP+G G PG+P G + G + P PPR Sbjct: 59 GRPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGQPPQG-GNQSQGP-PPR 116 Query: 154 PPEPIPASAAVTSGLTARGPNTSATPGPQKGRGSAERTNHIPKDKQRVAAPPP-PERPRV 212 P +P G +G N S P P+ G+ P+ + PPP P +P Sbjct: 117 PGKP--------EGPPPQGGNQSQGPPPRPGKPEGPP----PQGGNQSQGPPPRPGKPEG 164 Query: 213 PFCRGSSGLSVPTP-------PEHAGGRRKKFTRTRP-----LPRTSSFLSEVPSTRPLC 260 P +G + P P P GG + + RP P S+ P RP Sbjct: 165 PPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRP-- 222 Query: 261 ATSSSHSAPLPFFWSPLRNPSPRPAPACGELRLGRLSPPRADTGGSSSGGCSGPDSKHRT 320 P + + P P P G P R G G P + Sbjct: 223 ---GKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPPPGRPQG--PPPPGGNPQ 277 Query: 321 LPAPPAPTAWPAAGAPGAPNPAESRRGPGPAQGPP 355 P PP PA G P P + R P QG P Sbjct: 278 QPLPP-----PAGKPQGPPPPPQGGRPHRPPQGQP 307 Score = 51.2 bits (121), Expect = 2e-06 Identities = 65/240 (27%), Positives = 88/240 (36%), Gaps = 47/240 (19%) Query: 24 PRLAEALSQPTLRHSASALRPPRLSRGKDLKPRCG---RGPAHSPDPGEGCEAWRRLSAD 80 PR + QP + S PPR + + P+ G +GP P EG Sbjct: 94 PRPGKPEGQPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEG---------- 143 Query: 81 RWPRPA----SLSPRAALASAPGQKPQPARQAQLPRPVSGVR--PPPRG---RVGLSQAP 131 P P S P G PQ Q+Q P P G PPP+G G P Sbjct: 144 --PPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRP 201 Query: 132 GRPLGACARAKGIRLVNPSPPRPPEPIPASAAVTSGLTARGPNTSATPGPQKGRGSAERT 191 G+P G + G + P PPRP +P G ++G N P P G+ Sbjct: 202 GKPEGPPPQG-GNQSQGP-PPRPGKP--------EGPPSQGGNKPQGPPPHPGKPQGPP- 250 Query: 192 NHIPKDKQRVAAPPPPERPRVPFCRGS---------SGLSVPTPPEHAGGRRKKFTRTRP 242 P++ + PPPP RP+ P G +G PP GGR + + +P Sbjct: 251 ---PQEGNKPQRPPPPGRPQGPPPPGGNPQQPLPPPAGKPQGPPPPPQGGRPHRPPQGQP 307 >gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens] Length = 1003 Score = 57.4 bits (137), Expect = 2e-08 Identities = 90/372 (24%), Positives = 126/372 (33%), Gaps = 70/372 (18%) Query: 31 SQPTLRHSAS----ALRPPRLSRGKDLKPRCGRGPAHSPDPGEGCEAWRRLSADRWPRPA 86 + P + H+ S + RPP R P G + P+P +A+ L+ P Sbjct: 130 ASPQMFHTVSPGPPSARPP--CRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGGLFPP 187 Query: 87 SLSPRAALASAPGQKPQPARQAQLPRPVSGVRPPPRGRVGLSQAPGRPLGACARAKGIRL 146 L+ + S P+ + P P PPP + L+ AP GA R+ + Sbjct: 188 RLAD--PVPSGGSSSPRFLPRGNAPSPA----PPPPPAISLN-APSYNWGAALRSSLVPS 240 Query: 147 VNPSPPRP---------PEPIPASAAVTSGLTARGPNTSATPGPQKGRGSAERTNHIPKD 197 SPP P P S A+T N A PGP + T H+P Sbjct: 241 DLGSPPAPHASSSPPSDPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSSATMHLPLV 300 Query: 198 KQRVAAPPPPERPRVPFCRGSSGLSVPT--------PPEHAGGRRKKF------------ 237 + P E P P SS LS PP GRR + Sbjct: 301 LGPLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPSASHSSSLR 360 Query: 238 -TRTRP----------------LPRTSSFLSEVPSTRPLCATSSSHSAPLPFFWSPLRNP 280 ++ RP PR S + P +P S LP S L P Sbjct: 361 PSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPI-LPSVLSLLGLP 419 Query: 281 SPRPAPACGELRL----GRLSPPRADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAP 336 +P P+ + G L L PP + GS P +H P+ P T+ + P Sbjct: 420 TPGPSHSDGSFNLLGSDAHLPPPPTLSSGSP------PQPRHPIQPSLPGTTSGSLSSVP 473 Query: 337 GAPNPAESRRGP 348 GAP P + + P Sbjct: 474 GAPAPPAASKAP 485 Score = 50.1 bits (118), Expect = 4e-06 Identities = 95/376 (25%), Positives = 125/376 (33%), Gaps = 84/376 (22%) Query: 31 SQPTLRHSASALRPPRLSRGKDLKPRCGRGPAHSPDPGEGCEAWRRLSADRWPRPASLSP 90 S P L H + AL PP L +L GPA P +S+ P L P Sbjct: 256 SDPPLFHCSDALTPPPLPPSNNLPAH--PGPASQPP----------VSSATMHLPLVLGP 303 Query: 91 RAALASAPGQKPQPARQAQLPRPVSGVRPPP-------RGRVGLSQAPGRPLGACARAKG 143 + G P + L + + PP +GR +QAP + + + Sbjct: 304 LGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAP-----SASHSSS 358 Query: 144 IRLVNPSPPRPPEPIPASAAVTSGLTARGPNTSATPGPQKGRGSAERTNHIPKDKQRVAA 203 +R P RPP V L RGP T P++ R A P + + Sbjct: 359 LRPSQRRPRRPP-------TVFRLLEGRGPQT-----PRRSRPRA------PAPVPQPFS 400 Query: 204 PPPPERPRVPFCRGSSGLSVPTP-PEHAGGRRKKF-------------TRTRPLPR---- 245 P P +P +P GL PTP P H+ G + + P PR Sbjct: 401 LPEPSQPILPSVLSLLGL--PTPGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQ 458 Query: 246 ------TSSFLSEVPSTRPLCATSSSHSAPLPFFWSPLRNPSPRPAPAC--GELRLGRLS 297 TS LS VP A S + P P SP PAC L G Sbjct: 459 PSLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAF 518 Query: 298 P-PRADTGGSSSGGCSGPDSKHRTLP-------APPAP----TAWPAAGAPGAPNPAESR 345 P P + G + SG +G LP PP+P + + G P E Sbjct: 519 PFPSPEQGLALSG--AGFPGMLGALPLPLSLGQPPPSPLLNHSLFGVLTGGGGQPPPEPL 576 Query: 346 RGPGPAQGPPSRRDEP 361 P GPP EP Sbjct: 577 LPPPGGPGPPLAPGEP 592 Score = 42.7 bits (99), Expect = 6e-04 Identities = 87/356 (24%), Positives = 117/356 (32%), Gaps = 49/356 (13%) Query: 83 PRPASLSPRAALASAPGQKPQPARQAQLPRPVSGVRPPPRGRVGLSQAPGRPLGACARAK 142 P P+ L + G QP + LP P G PP APG P G Sbjct: 550 PPPSPLLNHSLFGVLTGGGGQPPPEPLLPPP-GGPGPP--------LAPGEPEGPSLLVA 600 Query: 143 GIRLVNPSPPRPPEPIPASAAVTS--GLTARGPNTSATPGPQKGRG--SAERTNHIPKDK 198 + PS PP P S + S L A GP G +G G S E + + D Sbjct: 601 SLLPPPPSDLLPPPSAPPSNLLASFLPLLALGPTAGDGEGSAEGAGGPSGEPFSGL-GDL 659 Query: 199 QRVAAPPPPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRTRPLPRTSSFLSEV--PST 256 + PP P + + + PP + + +P P TSS + P Sbjct: 660 SPLLFPPLSAPPTLIALNSALLAATLDPPSGTPPQPCVLSAPQPGPPTSSVTTATTDPGA 719 Query: 257 RPLCATSSSHSAPLPFFWSPL-----------RNPSPRPAPAC----GELRLGRLSPPRA 301 L S+ P P SPL SP P+ G L G+L Sbjct: 720 SSLGKAPSNSGRP-PQLLSPLLGASLLGDLSSLTSSPGALPSLLQPPGPLLSGQLGLQLL 778 Query: 302 DTGGSS---SGGCSGPDSKHRTLPAPPAPTAWPA--AGAPGAPNPAESRRGPGPAQGPP- 355 GG+ S S ++L PP P +P + E R P A PP Sbjct: 779 PGGGAPPPLSEASSPLACLLQSLQIPPEQPEAPCLPPESPASALEPEPARPPLSALAPPH 838 Query: 356 SRRDEPRRVVIAARECGREG-----------SELPPSGEETPGRRKSPSQSCKKGG 400 D P ++ R G+ G E P+ PG R+ P + K G Sbjct: 839 GSPDPPVPELLTGRGSGKRGRRGGGGLRGINGEARPARGRKPGSRREPGRLALKWG 894 >gi|47132519 Ras association and pleckstrin homology domains 1 isoform 1 [Homo sapiens] Length = 1250 Score = 57.0 bits (136), Expect = 3e-08 Identities = 95/387 (24%), Positives = 138/387 (35%), Gaps = 57/387 (14%) Query: 32 QPTLRHSASALRPPR--LSRGKDLKPRC-----GRGPAHSPDPGEGCEAWRRLSADRWPR 84 Q +HS + +PP + + + +KP+ G P P P SA + Sbjct: 674 QNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPG----SAMAQLK 729 Query: 85 PASLSPRAALASAPGQKPQPARQAQLPRPVSGVRPPPRGRVGLSQAPGRPLGACARAKGI 144 PA +P SAP P P + Q+ ++ V PP + P P+ A Sbjct: 730 PAPCAPSLPQFSAP---PPPLKIHQVQH-ITQVAPP-------TPPPPPPIPA------- 771 Query: 145 RLVNPSPPRPPEPIPASAA---VTSGLTARGPNTSATPGPQKGRGSAERTNHIPKDKQRV 201 L +PP+P IPA + V +T P T P P + A ++IP Sbjct: 772 PLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTP 831 Query: 202 AAPPPPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRTRPLPRTSSFLSEVPSTRPLCA 261 P PP P +P + P+P K+ P P T + P +P+ A Sbjct: 832 PVPVPP--PTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQP-LKPVPA 888 Query: 262 TSSSHSAPLPFF---WSPLRNPSPRPAPACGELRLGRLSPPRADTGGSSSGGCSGPDSKH 318 + S P W P P P P PP + SS P S Sbjct: 889 NVAPQSPPAVKAKPKWQPSSIPVPSPD----------FPPPPPE---SSLVFPPPPPSPV 935 Query: 319 RTLPAPPAPTAWPAAGAPGAPNPAESR-RGPGPAQGPPSRRDEPRRVVIAARECGREGSE 377 P PP PTA P G+P S+ PG + PP+ P+R G E E Sbjct: 936 PAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPT----PQRNSSIKSSSGAEHPE 991 Query: 378 -LPPSGEETPGRRKSPSQSCKKGGESI 403 PS + + P++S E++ Sbjct: 992 PKRPSVDSLVSKFTPPAESGSPSKETL 1018 Score = 45.8 bits (107), Expect = 7e-05 Identities = 68/284 (23%), Positives = 93/284 (32%), Gaps = 61/284 (21%) Query: 83 PRPASLSPRAALASAPGQKPQPARQ-AQLPRPVSGVRPPPRGRVGLSQAPGRPLGACARA 141 P PA+++P+ S P K +P Q + +P P PPP P L Sbjct: 885 PVPANVAPQ----SPPAVKAKPKWQPSSIPVPSPDFPPPP---------PESSL------ 925 Query: 142 KGIRLVNPSPPRPPEPIPASAAVTSGLTARGPNTSATPGPQKGRGSAERTNHIPKDKQR- 200 PP PP P+PA + P+ S +PG + + S+ P QR Sbjct: 926 -------VFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRN 978 Query: 201 -------VAAPPPPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRTRPLPRTSSFLSEV 253 A P P+RP V S +S TPP +G K+ P L+ Sbjct: 979 SSIKSSSGAEHPEPKRPSV-----DSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLS 1033 Query: 254 PSTRPLCATSSSHSAPLPF-----------FWSPLRNPSPRPAPACGELRLGRLSPPRAD 302 P SA P F SP + P P EL L + P Sbjct: 1034 GVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVF 1093 Query: 303 TGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAESRR 346 +G +S + P P W AP P +R Sbjct: 1094 SGNTSP----------KVAVVNPQPQQWSKMSVKKAPPPTRPKR 1127 Score = 33.1 bits (74), Expect = 0.47 Identities = 73/320 (22%), Positives = 96/320 (30%), Gaps = 80/320 (25%) Query: 72 EAWRR---LSADRWPRPASLSPRAALASAPGQKPQPA----RQAQLPRPVSGVRPPPRGR 124 EAW+R L R S++ R + P PQP A P P PPP Sbjct: 579 EAWKRGTQLEESSKARMESMN-RPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPP--- 634 Query: 125 VGLSQAPGRPLGACARAKGIRLVNPSPPRPPEPIPASAAVTSGLTA----------RGPN 174 P P P PP PP P+P+ +A ++G A R N Sbjct: 635 -----PPPPP--------------PPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQN 675 Query: 175 TS-------ATPGPQKGRGSAERTNHIPKDKQRVAAPPPPERPRVPF----------CRG 217 S P P + + + + V PPPP P P C Sbjct: 676 ASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAP 735 Query: 218 S-SGLSVPTPPEHAGGRRKKFTRTRPLPRTSSFLSEVPSTRPLCATSSSHSAPLPFFWSP 276 S S P PP + P P P P+ A + P P P Sbjct: 736 SLPQFSAPPPPLKIHQVQHITQVAPPTP---------PPPPPIPAPLPPQAPPKPLVTIP 786 Query: 277 LRNPSPRPAPACGELRLGRLSPPRADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAP 336 + AP + +PP P K PA P + P P Sbjct: 787 APTSTKTVAPVVTQAAPPTPTPP------------VPPAKKQPAFPASYIPPSPPTPPVP 834 Query: 337 GAPNPAESRRGPGPAQGPPS 356 P P ++ A+ PPS Sbjct: 835 -VPPPTLPKQQSFCAKPPPS 853 >gi|153281158 dual specificity phosphatase 8 [Homo sapiens] Length = 625 Score = 57.0 bits (136), Expect = 3e-08 Identities = 97/333 (29%), Positives = 121/333 (36%), Gaps = 56/333 (16%) Query: 87 SLSPRAALASAPGQK-------PQPARQAQLPRPVSGVRPPPRGRVGLSQAPGRPLGACA 139 SL AAL PG P PA A LPR PPP S A G A A Sbjct: 299 SLKLLAALQGDPGTPSGTPEPPPSPAAGAPLPR-----LPPPTSE---SAATGN---AAA 347 Query: 140 RAKGIRLVNPSPPRPPEPIPASAAVTSGLTARGPNTSATPGPQKGRGSAERTNHIPK--- 196 R G+ PP PP P PA++A+ GL RG + S+ R + I Sbjct: 348 REGGLS-AGGEPPAPPTP-PATSALQQGL--RGLHLSSDRLQDTNRLKRSFSLDIKSAYA 403 Query: 197 DKQRVAAPPPPERPRVP-FCRGSS------GLSVPTP--PEHAGGRRKKFTRTRPLPRTS 247 +R P PP+ P C+ S GLS P+P P+ A R + R RP P Sbjct: 404 PSRRPDGPGPPDPGEAPKLCKLDSPSGAALGLSSPSPDSPDAAPEARPR-PRRRPRP--- 459 Query: 248 SFLSEVPSTRPLCATSSSHSAPLPFFWSPLRNPSPRPAPACGELRLGRLSPPRADTGGSS 307 P+ P A S +HS L F + R P G L LS P G Sbjct: 460 ------PAGSP--ARSPAHSLGLNF------GDAARQTPRHG---LSALSAPGLPGPGQP 502 Query: 308 SG-GCSGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAESRRGPGPAQGPPSRRDEPRRVVI 366 +G G P P+P P + GA GA + G A GP D RR Sbjct: 503 AGPGAWAPPLDSPGTPSPDGPWCFSPEGAQGAGGVLFAPFGRAGAPGPGGGSDLRRREAA 562 Query: 367 AARECGREGSELPPSGEETPGRRKSPSQSCKKG 399 A ET +R+S ++G Sbjct: 563 RAEPRDARTGWPEEPAPETQFKRRSCQMEFEEG 595 >gi|182507165 thymus expressed gene 3-like [Homo sapiens] Length = 629 Score = 56.6 bits (135), Expect = 4e-08 Identities = 105/407 (25%), Positives = 133/407 (32%), Gaps = 63/407 (15%) Query: 39 ASALRPPRLSRGKDLKPRCGRGPAHSPDPGEG---CEAWRRLSADRWPRPASLSPRAALA 95 A A+R PR CGR P SPD G + + R R + PR + Sbjct: 223 AVAMRSPR---------PCGRPPTDSPDAGGAGRPLDGYISALLRRRRRRGAGQPRTSPG 273 Query: 96 SAPGQKPQPARQAQLP---RPVSGVRPPPRGRVGLSQAPGRPLG--ACARAKGIRLVNPS 150 A G + Q P P G P R L + G P A +RA + + Sbjct: 274 GADGGPRRQNSVRQRPPDASPSPGSARPAR-EPSLERVGGHPTSPAALSRAWASSWESEA 332 Query: 151 PPRPPEPIPASAAVTSGLTARGPNTSATPGPQKGR----GSAERTNHIPKDKQR-VAAPP 205 P P P A + S R PG Q G A R P + R V P Sbjct: 333 APEPAAPPAAPSPPDSPAEGRLVKAQYIPGAQAATRGLPGRAARRKPPPLTRGRSVEQSP 392 Query: 206 PPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRTRPLPRTSSFLSEVPSTRPLCATSSS 265 P ERPR G G R +K +R++ S VPS P T+ Sbjct: 393 PRERPRAA---GRRGRMAEASGRRGSPRARKASRSQSETSLLGRASAVPSGPPKYPTAER 449 Query: 266 HSAPLPFFWSPLRNPSPR-PAPACGELRL-----------GRLSPPRADT------GGSS 307 P P R P+P A A G R GR PRA G S Sbjct: 450 EEPRPP---RPRRGPAPTLAAQAAGSCRRWRSTAEIDAADGRRVRPRAPAARVPGPGPSP 506 Query: 308 SG-------GCSGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAES--RRGPGPAQGPPSRR 358 S GC+G DS+ P PA G G +ES G PA S Sbjct: 507 SAPQRRLLYGCAGSDSECSAGRLGPLGRRGPAGGVGGGYGESESSASEGESPAFSSASSD 566 Query: 359 DE-------PRRVVIAARECGREGSELPPSGEETPGRRKSPSQSCKK 398 + P+++V A G P+G + S + KK Sbjct: 567 SDGSGGLVWPQQLVAATAASGGGAGAGAPAGPAKVFVKIKASHALKK 613 Score = 42.4 bits (98), Expect = 8e-04 Identities = 80/307 (26%), Positives = 104/307 (33%), Gaps = 63/307 (20%) Query: 123 GRVGLSQAPGRPLGACARAKGIRLVNPSPPRPPEPIPASAAVTSGLTARGPNTSATPGPQ 182 GR+G S+ G + A R K + +PS P E + A AAV +A P + GP+ Sbjct: 147 GRLGPSEPRG--IYASERPKSLGDASPSAP---EVVGARAAVPRSFSAPYPTAGGSAGPE 201 Query: 183 KGRGSAER------------TNHIPKDKQRVAAPPPPERPRVPFC--------------R 216 SAER + + R PP + P R Sbjct: 202 -ACSSAERRARAGPFLTPSPLHAVAMRSPRPCGRPPTDSPDAGGAGRPLDGYISALLRRR 260 Query: 217 GSSGLSVP-TPPEHAGG--RRKKFTRTRPLPRTSSFLSEVPSTRPLCATSSSH---SAPL 270 G P T P A G RR+ R RP + S S P+ P H A L Sbjct: 261 RRRGAGQPRTSPGGADGGPRRQNSVRQRPPDASPSPGSARPAREPSLERVGGHPTSPAAL 320 Query: 271 PFFWSPLRNPSPRPAPACGELRLGRLSPPRADTGGSSSGGCSGPDS--KHRTLPAPPAPT 328 W+ P PA +PP A S PDS + R + A P Sbjct: 321 SRAWASSWESEAAPEPA---------APPAAP---------SPPDSPAEGRLVKAQYIPG 362 Query: 329 AWPAAGAPGAPNPAESRRGPGPAQGPPSRRDEPRRVVIAARECGREGSELPPSGEETPGR 388 A A G P A R+ P +G + PR R GR G SG R Sbjct: 363 A--QAATRGLPGRAARRKPPPLTRGRSVEQSPPRE---RPRAAGRRGRMAEASGRRGSPR 417 Query: 389 RKSPSQS 395 + S+S Sbjct: 418 ARKASRS 424 >gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Homo sapiens] Length = 247 Score = 56.6 bits (135), Expect = 4e-08 Identities = 75/267 (28%), Positives = 89/267 (33%), Gaps = 68/267 (25%) Query: 99 GQKPQPARQAQLPRPVSGVR--PPPRG---RVGLSQAPGRPLGACARAKGIRLVNPSPPR 153 G++PQ Q Q P P G PPP+G G PG+P G + P P Sbjct: 38 GRRPQGGNQPQRPPPPPGKPQGPPPQGGNQSQGPPPPPGKPEGRPPQGGNQSQGPPPHPG 97 Query: 154 PPEPIPASAAVTSGLTARGPNTSATPGPQKGRGSAERTNHIPKDKQRVAAPPPPERPRVP 213 PE P S T P P PQ G S H P PPPP +P P Sbjct: 98 KPERPPPQGGNQSQGTPPPPGKPERPPPQGGNQS-----HRP--------PPPPGKPERP 144 Query: 214 FCRGSSGLSVPTPPEHAGGRRKKFTRTRPLPRTSSFLSEVPSTRPLCATSSSHSAPLPFF 273 +G G PP H G P P + S SA Sbjct: 145 PPQG--GNQSQGPPPHPGK---------------------PEGPPPQEGNKSRSA----- 176 Query: 274 WSPLRNPSPRPAPACGELRLGRLSPPRADTGGSSSGGCSGPDSKHRTLPA---PPAPTAW 330 R+P +P PP+ + G+ G P PA P P A Sbjct: 177 ----RSPPGKPQ-----------GPPQQE--GNKPQGPPPPGKPQGPPPAGGNPQQPQAP 219 Query: 331 PAAGAPGAPNPAESRRGPGPAQG--PP 355 PA G P P + R P PAQG PP Sbjct: 220 PAGKPQGPPPPPQGGRPPRPAQGQQPP 246 Score = 32.0 bits (71), Expect = 1.1 Identities = 26/86 (30%), Positives = 34/86 (39%), Gaps = 15/86 (17%) Query: 38 SASALRPPRLSRGKDLKPRCGRGPAHSPDPGEGCEAWRRLSADRWPRPAS---LSPRAAL 94 S SA PP +G + G P P PG+ + P PA P+A Sbjct: 173 SRSARSPPGKPQGPPQQE--GNKPQGPPPPGK----------PQGPPPAGGNPQQPQAPP 220 Query: 95 ASAPGQKPQPARQAQLPRPVSGVRPP 120 A P P P + + PRP G +PP Sbjct: 221 AGKPQGPPPPPQGGRPPRPAQGQQPP 246 >gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] Length = 904 Score = 56.6 bits (135), Expect = 4e-08 Identities = 113/449 (25%), Positives = 154/449 (34%), Gaps = 99/449 (22%) Query: 2 SELESGEIRSEEGRPTTESRIRPR----LAEALSQPTLRHSAS--ALRPPRLSRG----- 50 S S RS +P + PR L+ + S P RH S A PP+ Sbjct: 360 SSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQ 419 Query: 51 --KDLKPRCGRGPAHSPDP---GEGCEAWRRLSADRWPRPASLSP-------RAALASAP 98 + K R P + +G E S PR LS + A A + Sbjct: 420 SNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSV 479 Query: 99 GQKPQPARQAQLPRPVSGV-------RPP----PRGRVGLSQ--APGRPLGACARAK--- 142 Q+ Q RQ Q SG RP G VG + +P R R + Sbjct: 480 QQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKE 539 Query: 143 ----GIRLVNPSPP-----RPPEPIPASAAVTSGLTARGPNTSATPGPQKGRGSAERTNH 193 G R +PSPP R P P P T P TP P R S + Sbjct: 540 TSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRR---TPTPPPRRRTPSPPPRRRSPSPRRY 596 Query: 194 IPKDKQRVAAPPPPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRTRPLPRTSSFLSEV 253 P ++R + PPP+R S P PP+ R P P Sbjct: 597 SPPIQRRYSPSPPPKRRTA---------SPPPPPKR---------RASPSP--------- 629 Query: 254 PSTRPLCATSSSHSAPLPFFWSPLRNPSPRPAPACGELRLGRLSPPRADTGGSSSGGCSG 313 P R + SHS P SP+ + R +P+ SP R+ S Sbjct: 630 PPKRRV-----SHSPPPKQRSSPV---TKRRSPSLSSKHRKGSSPSRSTREARS----PQ 677 Query: 314 PDSKHRTLPAPPAP--TAWPAAGAPGAPNPAESRRGPGPAQGP---PSRRDEPRRVVIAA 368 P+ +H P P AP ++ P GA + + R+ P P+ P SR EP+++ AA Sbjct: 678 PNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAA 737 Query: 369 ----RECGREGSELPPSGEETPGRRKSPS 393 + R S SG P +K P+ Sbjct: 738 SPSPQSVRRVSSSRSVSGSPEPAAKKPPA 766 Score = 54.7 bits (130), Expect = 2e-07 Identities = 68/266 (25%), Positives = 98/266 (36%), Gaps = 48/266 (18%) Query: 148 NPSPPRPPEPIPASAAVTSGLTARGPNTSATPGPQKGRGSAERTNHIPKDKQRVAAPPPP 207 +PSP R P+ + + R S +P P + E+T +P+ +V P Sbjct: 179 SPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEK--KEKTPELPEPSVKVKEPSVQ 236 Query: 208 ERPRVPFCRGSSGLSVPTP----------PEHAGGRRKKFTRTRPLPRTSSFLSEVPSTR 257 E S L VP P PE + K+ +TRP R+ S +R Sbjct: 237 EATST-----SDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSR 291 Query: 258 PLCATSSSHSAPLPFF------WSPLRNPSPRPAPACGELRLGRLSPPRADTGGSSSGGC 311 S SH+ P +SP R PSPR P+ R +PPR Sbjct: 292 -----SPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPR-----RRTPPRR---------- 331 Query: 312 SGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAESRRGPGPAQGPPSRRDEP----RRVVIA 367 P +HR +P +A G+ + + S R P + PP R P RR+ + Sbjct: 332 MPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPS 391 Query: 368 ARECGREGSELPPSGEETPGRRKSPS 393 A R PP+ P R SP+ Sbjct: 392 ASPPRRRHRPSPPA-TPPPKTRHSPT 416 Score = 47.8 bits (112), Expect = 2e-05 Identities = 93/387 (24%), Positives = 127/387 (32%), Gaps = 59/387 (15%) Query: 43 RPPRLSRGKDLKPRCGRGPAHSPDPGEGCEAWRRLSADRWPRPASLSPRAALASAPGQKP 102 RP SR K R P+H+ RP + + +P ++P Sbjct: 275 RPRSRSRSKSRSRTRSRSPSHT-------------------RPRRRHRSRSRSYSPRRRP 315 Query: 103 QPARQAQLPR--PVSGVRPPPRGRVGLSQAPGRPLGACARAKGIRLVNPSPPRPPEPIPA 160 P R+ R P + PPPR R S R + + + + S R P P Sbjct: 316 SPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPP 375 Query: 161 SAAVTSGLTARGPNTSATPGPQKGRGSAERTNHIPKDKQRVAAPPPPERPRVPFCRGSSG 220 + R + SA+P ++ R S T P + P R R S G Sbjct: 376 KRTSSPPRKTRRLSPSASPPRRRHRPSPPATP--PPKTRHSPTPQQSNRTRKSRVSVSPG 433 Query: 221 LSVPTPPEHAGGRRKKFTRTRPLPRTSSFLSE--------------VPSTRPLCATSSSH 266 + +H G +++ P PR LSE V R + Sbjct: 434 RTSGKVTKHKGTEKRESPSPAPKPRKVE-LSESEEDKGGKMAAADSVQQRRQYRRQNQQS 492 Query: 267 SAPLPFFWSPLRNPSPRPAPACGEL-RLGRLSPPR-ADTGGSSSGGCSGPDSKHRTLPAP 324 S+ S R GE+ R R SP R A + P + R P+P Sbjct: 493 SSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSP 552 Query: 325 P------APTAWPAAGAPGAPNPAESRRGPGPAQGPPSRRD-EPRRVVIAARECGREGSE 377 P +P+ P P P RR P P PP RR PRR + R S Sbjct: 553 PPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSP---PPRRRSPSPRRY---SPPIQRRYSP 606 Query: 378 LPPSGEET------PGRRKSPSQSCKK 398 PP T P RR SPS K+ Sbjct: 607 SPPPKRRTASPPPPPKRRASPSPPPKR 633 Score = 42.7 bits (99), Expect = 6e-04 Identities = 52/227 (22%), Positives = 79/227 (34%), Gaps = 42/227 (18%) Query: 31 SQPTLRHSASALRPPRLSRGKDLKPRCGRGPAHSPDPGEGCEAWRRLSADRWPRPASLSP 90 S P R +AS PP+ P+ R +HSP P + R S R SLS Sbjct: 607 SPPPKRRTASPPPPPKRRASPSPPPK--RRVSHSPPPKQ------RSSPVTKRRSPSLSS 658 Query: 91 RAALASAPGQKPQPARQAQ---------LPRPVSGVRPPPRGRVGLSQAPGRPLGACARA 141 + S+P + + AR Q PR PP R G S +P R Sbjct: 659 KHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPST 718 Query: 142 KGIRLVNPSP------------PRPPEPIPASAAVTSGLTARGPNTSATPGPQKGRGSAE 189 + IR V+ +P P+ + +S +V+ A P P + + + Sbjct: 719 RPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPST 778 Query: 190 RTNHIPKDKQRVAAPPPPERPRVPFCRGSSGLSVPTPPEHAGGRRKK 236 + K+ + P P PR + GG++KK Sbjct: 779 NWSPAVPVKKAKSPTPSPSPPR-------------NSDQEGGGKKKK 812 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.312 0.132 0.416 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 25,967,489 Number of Sequences: 37866 Number of extensions: 2011408 Number of successful extensions: 20725 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 283 Number of HSP's successfully gapped in prelim test: 2076 Number of HSP's that attempted gapping in prelim test: 11105 Number of HSP's gapped (non-prelim): 8270 length of query: 414 length of database: 18,247,518 effective HSP length: 105 effective length of query: 309 effective length of database: 14,271,588 effective search space: 4409920692 effective search space used: 4409920692 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.