Search of human proteins with 83977442

Search of human proteins with 83977442

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|83977442 5-aminolevulinate synthase 2 isoform a precursor
[Homo sapiens]
         (587 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|83977442 5-aminolevulinate synthase 2 isoform a precursor [Ho...  1193   0.0  
gi|83977444 5-aminolevulinate synthase 2 isoform c precursor [Ho...  1103   0.0  
gi|83977440 5-aminolevulinate synthase 2 isoform b precursor [Ho...  1103   0.0  
gi|40316939 5-aminolevulinate synthase 1 [Homo sapiens]               713   0.0  
gi|4502025 5-aminolevulinate synthase 1 [Homo sapiens]                713   0.0  
gi|7657118 glycine C-acetyltransferase precursor [Homo sapiens]       223   3e-58
gi|119220554 serine palmitoyltransferase, long chain base subuni...   172   6e-43
gi|4758668 serine palmitoyltransferase, long chain base subunit ...   154   2e-37
gi|5454084 serine palmitoyltransferase subunit 1 isoform a [Homo...   123   5e-28
gi|167000400 gamma-aminobutyric acid (GABA) B receptor 1 isoform...    31   2.8  
gi|11497612 gamma-aminobutyric acid (GABA) B receptor 1 isoform ...    31   2.8  
gi|10835015 gamma-aminobutyric acid (GABA) B receptor 1 isoform ...    31   2.8  
gi|66529005 ATP-binding cassette, sub-family C, member 5 isoform...    31   3.6  
gi|30474871 serine palmitoyltransferase subunit 1 isoform b [Hom...    30   6.2  
gi|41872631 fatty acid synthase [Homo sapiens]                         30   8.1  

>gi|83977442 5-aminolevulinate synthase 2 isoform a precursor [Homo
           sapiens]
          Length = 587

 Score = 1193 bits (3087), Expect = 0.0
 Identities = 587/587 (100%), Positives = 587/587 (100%)

Query: 1   MVTAAMLLQCCPVLARGPTSLLGKVVKTHQFLFGIGRCPILATQGPNCSQIHLKATKAGG 60
           MVTAAMLLQCCPVLARGPTSLLGKVVKTHQFLFGIGRCPILATQGPNCSQIHLKATKAGG
Sbjct: 1   MVTAAMLLQCCPVLARGPTSLLGKVVKTHQFLFGIGRCPILATQGPNCSQIHLKATKAGG 60

Query: 61  DSPSWAKGHCPFMLSELQDGKSKIVQKAAPEVQEDVKAFKTDLPSSLVSVSLRKPFSGPQ 120
           DSPSWAKGHCPFMLSELQDGKSKIVQKAAPEVQEDVKAFKTDLPSSLVSVSLRKPFSGPQ
Sbjct: 61  DSPSWAKGHCPFMLSELQDGKSKIVQKAAPEVQEDVKAFKTDLPSSLVSVSLRKPFSGPQ 120

Query: 121 EQEQISGKVTHLIQNNMPGNYVFSYDQFFRDKIMEKKQDHTYRVFKTVNRWADAYPFAQH 180
           EQEQISGKVTHLIQNNMPGNYVFSYDQFFRDKIMEKKQDHTYRVFKTVNRWADAYPFAQH
Sbjct: 121 EQEQISGKVTHLIQNNMPGNYVFSYDQFFRDKIMEKKQDHTYRVFKTVNRWADAYPFAQH 180

Query: 181 FSEASVASKDVSVWCSNDYLGMSRHPQVLQATQETLQRHGAGAGGTRNISGTSKFHVELE 240
           FSEASVASKDVSVWCSNDYLGMSRHPQVLQATQETLQRHGAGAGGTRNISGTSKFHVELE
Sbjct: 181 FSEASVASKDVSVWCSNDYLGMSRHPQVLQATQETLQRHGAGAGGTRNISGTSKFHVELE 240

Query: 241 QELAELHQKDSALLFSSCFVANDSTLFTLAKILPGCEIYSDAGNHASMIQGIRNSGAAKF 300
           QELAELHQKDSALLFSSCFVANDSTLFTLAKILPGCEIYSDAGNHASMIQGIRNSGAAKF
Sbjct: 241 QELAELHQKDSALLFSSCFVANDSTLFTLAKILPGCEIYSDAGNHASMIQGIRNSGAAKF 300

Query: 301 VFRHNDPDHLKKLLEKSNPKIPKIVAFETVHSMDGAICPLEELCDVSHQYGALTFVDEVH 360
           VFRHNDPDHLKKLLEKSNPKIPKIVAFETVHSMDGAICPLEELCDVSHQYGALTFVDEVH
Sbjct: 301 VFRHNDPDHLKKLLEKSNPKIPKIVAFETVHSMDGAICPLEELCDVSHQYGALTFVDEVH 360

Query: 361 AVGLYGSRGAGIGERDGIMHKIDIISGTLGKAFGCVGGYIASTRDLVDMVRSYAAGFIFT 420
           AVGLYGSRGAGIGERDGIMHKIDIISGTLGKAFGCVGGYIASTRDLVDMVRSYAAGFIFT
Sbjct: 361 AVGLYGSRGAGIGERDGIMHKIDIISGTLGKAFGCVGGYIASTRDLVDMVRSYAAGFIFT 420

Query: 421 TSLPPMVLSGALESVRLLKGEEGQALRRAHQRNVKHMRQLLMDRGLPVIPCPSHIIPIRV 480
           TSLPPMVLSGALESVRLLKGEEGQALRRAHQRNVKHMRQLLMDRGLPVIPCPSHIIPIRV
Sbjct: 421 TSLPPMVLSGALESVRLLKGEEGQALRRAHQRNVKHMRQLLMDRGLPVIPCPSHIIPIRV 480

Query: 481 GNAALNSKLCDLLLSKHGIYVQAINYPTVPRGEELLRLAPSPHHSPQMMEDFVEKLLLAW 540
           GNAALNSKLCDLLLSKHGIYVQAINYPTVPRGEELLRLAPSPHHSPQMMEDFVEKLLLAW
Sbjct: 481 GNAALNSKLCDLLLSKHGIYVQAINYPTVPRGEELLRLAPSPHHSPQMMEDFVEKLLLAW 540

Query: 541 TAVGLPLQDVSVAACNFCRRPVHFELMSEWERSYFGNMGPQYVTTYA 587
           TAVGLPLQDVSVAACNFCRRPVHFELMSEWERSYFGNMGPQYVTTYA
Sbjct: 541 TAVGLPLQDVSVAACNFCRRPVHFELMSEWERSYFGNMGPQYVTTYA 587


>gi|83977444 5-aminolevulinate synthase 2 isoform c precursor [Homo
           sapiens]
          Length = 574

 Score = 1103 bits (2852), Expect = 0.0
 Identities = 550/587 (93%), Positives = 550/587 (93%), Gaps = 37/587 (6%)

Query: 1   MVTAAMLLQCCPVLARGPTSLLGKVVKTHQFLFGIGRCPILATQGPNCSQIHLKATKAGG 60
           MVTAAMLLQCCPVLARGPTSLLGKVVKTHQFLFGIGRCPILATQGPNCSQIHLKATKAGG
Sbjct: 25  MVTAAMLLQCCPVLARGPTSLLGKVVKTHQFLFGIGRCPILATQGPNCSQIHLKATKAGG 84

Query: 61  DSPSWAKGHCPFMLSELQDGKSKIVQKAAPEVQEDVKAFKTDLPSSLVSVSLRKPFSGPQ 120
           DSPSWAKGHCPFMLSELQDGKSKIVQKAAPEVQEDVKAFKT                   
Sbjct: 85  DSPSWAKGHCPFMLSELQDGKSKIVQKAAPEVQEDVKAFKT------------------- 125

Query: 121 EQEQISGKVTHLIQNNMPGNYVFSYDQFFRDKIMEKKQDHTYRVFKTVNRWADAYPFAQH 180
                             GNYVFSYDQFFRDKIMEKKQDHTYRVFKTVNRWADAYPFAQH
Sbjct: 126 ------------------GNYVFSYDQFFRDKIMEKKQDHTYRVFKTVNRWADAYPFAQH 167

Query: 181 FSEASVASKDVSVWCSNDYLGMSRHPQVLQATQETLQRHGAGAGGTRNISGTSKFHVELE 240
           FSEASVASKDVSVWCSNDYLGMSRHPQVLQATQETLQRHGAGAGGTRNISGTSKFHVELE
Sbjct: 168 FSEASVASKDVSVWCSNDYLGMSRHPQVLQATQETLQRHGAGAGGTRNISGTSKFHVELE 227

Query: 241 QELAELHQKDSALLFSSCFVANDSTLFTLAKILPGCEIYSDAGNHASMIQGIRNSGAAKF 300
           QELAELHQKDSALLFSSCFVANDSTLFTLAKILPGCEIYSDAGNHASMIQGIRNSGAAKF
Sbjct: 228 QELAELHQKDSALLFSSCFVANDSTLFTLAKILPGCEIYSDAGNHASMIQGIRNSGAAKF 287

Query: 301 VFRHNDPDHLKKLLEKSNPKIPKIVAFETVHSMDGAICPLEELCDVSHQYGALTFVDEVH 360
           VFRHNDPDHLKKLLEKSNPKIPKIVAFETVHSMDGAICPLEELCDVSHQYGALTFVDEVH
Sbjct: 288 VFRHNDPDHLKKLLEKSNPKIPKIVAFETVHSMDGAICPLEELCDVSHQYGALTFVDEVH 347

Query: 361 AVGLYGSRGAGIGERDGIMHKIDIISGTLGKAFGCVGGYIASTRDLVDMVRSYAAGFIFT 420
           AVGLYGSRGAGIGERDGIMHKIDIISGTLGKAFGCVGGYIASTRDLVDMVRSYAAGFIFT
Sbjct: 348 AVGLYGSRGAGIGERDGIMHKIDIISGTLGKAFGCVGGYIASTRDLVDMVRSYAAGFIFT 407

Query: 421 TSLPPMVLSGALESVRLLKGEEGQALRRAHQRNVKHMRQLLMDRGLPVIPCPSHIIPIRV 480
           TSLPPMVLSGALESVRLLKGEEGQALRRAHQRNVKHMRQLLMDRGLPVIPCPSHIIPIRV
Sbjct: 408 TSLPPMVLSGALESVRLLKGEEGQALRRAHQRNVKHMRQLLMDRGLPVIPCPSHIIPIRV 467

Query: 481 GNAALNSKLCDLLLSKHGIYVQAINYPTVPRGEELLRLAPSPHHSPQMMEDFVEKLLLAW 540
           GNAALNSKLCDLLLSKHGIYVQAINYPTVPRGEELLRLAPSPHHSPQMMEDFVEKLLLAW
Sbjct: 468 GNAALNSKLCDLLLSKHGIYVQAINYPTVPRGEELLRLAPSPHHSPQMMEDFVEKLLLAW 527

Query: 541 TAVGLPLQDVSVAACNFCRRPVHFELMSEWERSYFGNMGPQYVTTYA 587
           TAVGLPLQDVSVAACNFCRRPVHFELMSEWERSYFGNMGPQYVTTYA
Sbjct: 528 TAVGLPLQDVSVAACNFCRRPVHFELMSEWERSYFGNMGPQYVTTYA 574


>gi|83977440 5-aminolevulinate synthase 2 isoform b precursor [Homo
           sapiens]
          Length = 550

 Score = 1103 bits (2852), Expect = 0.0
 Identities = 550/587 (93%), Positives = 550/587 (93%), Gaps = 37/587 (6%)

Query: 1   MVTAAMLLQCCPVLARGPTSLLGKVVKTHQFLFGIGRCPILATQGPNCSQIHLKATKAGG 60
           MVTAAMLLQCCPVLARGPTSLLGKVVKTHQFLFGIGRCPILATQGPNCSQIHLKATKAGG
Sbjct: 1   MVTAAMLLQCCPVLARGPTSLLGKVVKTHQFLFGIGRCPILATQGPNCSQIHLKATKAGG 60

Query: 61  DSPSWAKGHCPFMLSELQDGKSKIVQKAAPEVQEDVKAFKTDLPSSLVSVSLRKPFSGPQ 120
           DSPSWAKGHCPFMLSELQDGKSKIVQKAAPEVQEDVKAFKT                   
Sbjct: 61  DSPSWAKGHCPFMLSELQDGKSKIVQKAAPEVQEDVKAFKT------------------- 101

Query: 121 EQEQISGKVTHLIQNNMPGNYVFSYDQFFRDKIMEKKQDHTYRVFKTVNRWADAYPFAQH 180
                             GNYVFSYDQFFRDKIMEKKQDHTYRVFKTVNRWADAYPFAQH
Sbjct: 102 ------------------GNYVFSYDQFFRDKIMEKKQDHTYRVFKTVNRWADAYPFAQH 143

Query: 181 FSEASVASKDVSVWCSNDYLGMSRHPQVLQATQETLQRHGAGAGGTRNISGTSKFHVELE 240
           FSEASVASKDVSVWCSNDYLGMSRHPQVLQATQETLQRHGAGAGGTRNISGTSKFHVELE
Sbjct: 144 FSEASVASKDVSVWCSNDYLGMSRHPQVLQATQETLQRHGAGAGGTRNISGTSKFHVELE 203

Query: 241 QELAELHQKDSALLFSSCFVANDSTLFTLAKILPGCEIYSDAGNHASMIQGIRNSGAAKF 300
           QELAELHQKDSALLFSSCFVANDSTLFTLAKILPGCEIYSDAGNHASMIQGIRNSGAAKF
Sbjct: 204 QELAELHQKDSALLFSSCFVANDSTLFTLAKILPGCEIYSDAGNHASMIQGIRNSGAAKF 263

Query: 301 VFRHNDPDHLKKLLEKSNPKIPKIVAFETVHSMDGAICPLEELCDVSHQYGALTFVDEVH 360
           VFRHNDPDHLKKLLEKSNPKIPKIVAFETVHSMDGAICPLEELCDVSHQYGALTFVDEVH
Sbjct: 264 VFRHNDPDHLKKLLEKSNPKIPKIVAFETVHSMDGAICPLEELCDVSHQYGALTFVDEVH 323

Query: 361 AVGLYGSRGAGIGERDGIMHKIDIISGTLGKAFGCVGGYIASTRDLVDMVRSYAAGFIFT 420
           AVGLYGSRGAGIGERDGIMHKIDIISGTLGKAFGCVGGYIASTRDLVDMVRSYAAGFIFT
Sbjct: 324 AVGLYGSRGAGIGERDGIMHKIDIISGTLGKAFGCVGGYIASTRDLVDMVRSYAAGFIFT 383

Query: 421 TSLPPMVLSGALESVRLLKGEEGQALRRAHQRNVKHMRQLLMDRGLPVIPCPSHIIPIRV 480
           TSLPPMVLSGALESVRLLKGEEGQALRRAHQRNVKHMRQLLMDRGLPVIPCPSHIIPIRV
Sbjct: 384 TSLPPMVLSGALESVRLLKGEEGQALRRAHQRNVKHMRQLLMDRGLPVIPCPSHIIPIRV 443

Query: 481 GNAALNSKLCDLLLSKHGIYVQAINYPTVPRGEELLRLAPSPHHSPQMMEDFVEKLLLAW 540
           GNAALNSKLCDLLLSKHGIYVQAINYPTVPRGEELLRLAPSPHHSPQMMEDFVEKLLLAW
Sbjct: 444 GNAALNSKLCDLLLSKHGIYVQAINYPTVPRGEELLRLAPSPHHSPQMMEDFVEKLLLAW 503

Query: 541 TAVGLPLQDVSVAACNFCRRPVHFELMSEWERSYFGNMGPQYVTTYA 587
           TAVGLPLQDVSVAACNFCRRPVHFELMSEWERSYFGNMGPQYVTTYA
Sbjct: 504 TAVGLPLQDVSVAACNFCRRPVHFELMSEWERSYFGNMGPQYVTTYA 550


>gi|40316939 5-aminolevulinate synthase 1 [Homo sapiens]
          Length = 640

 Score =  713 bits (1840), Expect = 0.0
 Identities = 357/557 (64%), Positives = 438/557 (78%), Gaps = 23/557 (4%)

Query: 44  QGPNCSQIHLKATK--AGGDSPSWAKG---HCPFMLSELQDGKSKIVQKAAPEVQEDVKA 98
           Q P+ SQ     T+  +G   P+ ++G    CPF+ +++    S +  KA+ E+QEDV+ 
Sbjct: 77  QTPDGSQQSPDGTQLPSGHPLPATSQGTASKCPFLAAQMNQRGSSVFCKASLELQEDVQE 136

Query: 99  F--------KTDLPSSLVSVS--------LRKPFSGPQEQEQISGKVTHLIQNNMPGNY- 141
                    +T    S+VSV         L K F     Q+Q   +V+HL+Q+N+P +  
Sbjct: 137 MNAVRKEVAETSAGPSVVSVKTDGGDPSGLLKNFQDIM-QKQRPERVSHLLQDNLPKSVS 195

Query: 142 VFSYDQFFRDKIMEKKQDHTYRVFKTVNRWADAYPFAQHFSEASVASKDVSVWCSNDYLG 201
            F YD+FF  KI EKK DHTYRVFKTVNR A  +P A  +S++ +  K VSVWCSNDYLG
Sbjct: 196 TFQYDRFFEKKIDEKKNDHTYRVFKTVNRRAHIFPMADDYSDSLITKKQVSVWCSNDYLG 255

Query: 202 MSRHPQVLQATQETLQRHGAGAGGTRNISGTSKFHVELEQELAELHQKDSALLFSSCFVA 261
           MSRHP+V  A  +TL++HGAGAGGTRNISGTSKFHV+LE+ELA+LH KD+ALLFSSCFVA
Sbjct: 256 MSRHPRVCGAVMDTLKQHGAGAGGTRNISGTSKFHVDLERELADLHGKDAALLFSSCFVA 315

Query: 262 NDSTLFTLAKILPGCEIYSDAGNHASMIQGIRNSGAAKFVFRHNDPDHLKKLLEKSNPKI 321
           NDSTLFTLAK++PGCEIYSD+GNHASMIQGIRNS   K++FRHND  HL++LL++S+P +
Sbjct: 316 NDSTLFTLAKMMPGCEIYSDSGNHASMIQGIRNSRVPKYIFRHNDVSHLRELLQRSDPSV 375

Query: 322 PKIVAFETVHSMDGAICPLEELCDVSHQYGALTFVDEVHAVGLYGSRGAGIGERDGIMHK 381
           PKIVAFETVHSMDGA+CPLEELCDV+H++GA+TFVDEVHAVGLYG+RG GIG+RDG+M K
Sbjct: 376 PKIVAFETVHSMDGAVCPLEELCDVAHEFGAITFVDEVHAVGLYGARGGGIGDRDGVMPK 435

Query: 382 IDIISGTLGKAFGCVGGYIASTRDLVDMVRSYAAGFIFTTSLPPMVLSGALESVRLLKGE 441
           +DIISGTLGKAFGCVGGYIAST  L+D VRSYAAGFIFTTSLPPM+L+GALESVR+LK  
Sbjct: 436 MDIISGTLGKAFGCVGGYIASTSSLIDTVRSYAAGFIFTTSLPPMLLAGALESVRILKSA 495

Query: 442 EGQALRRAHQRNVKHMRQLLMDRGLPVIPCPSHIIPIRVGNAALNSKLCDLLLSKHGIYV 501
           EG+ LRR HQRNVK MRQ+LMD GLPV+ CPSHIIP+RV +AA N+++CD L+S+H IYV
Sbjct: 496 EGRVLRRQHQRNVKLMRQMLMDAGLPVVHCPSHIIPVRVADAAKNTEVCDELMSRHNIYV 555

Query: 502 QAINYPTVPRGEELLRLAPSPHHSPQMMEDFVEKLLLAWTAVGLPLQDVSVAACNFCRRP 561
           QAINYPTVPRGEELLR+AP+PHH+PQMM  F+E LL+ W  VGL L+  S A CNFCRRP
Sbjct: 556 QAINYPTVPRGEELLRIAPTPHHTPQMMNYFLENLLVTWKQVGLELKPHSSAECNFCRRP 615

Query: 562 VHFELMSEWERSYFGNM 578
           +HFE+MSE E+SYF  +
Sbjct: 616 LHFEVMSEREKSYFSGL 632


>gi|4502025 5-aminolevulinate synthase 1 [Homo sapiens]
          Length = 640

 Score =  713 bits (1840), Expect = 0.0
 Identities = 357/557 (64%), Positives = 438/557 (78%), Gaps = 23/557 (4%)

Query: 44  QGPNCSQIHLKATK--AGGDSPSWAKG---HCPFMLSELQDGKSKIVQKAAPEVQEDVKA 98
           Q P+ SQ     T+  +G   P+ ++G    CPF+ +++    S +  KA+ E+QEDV+ 
Sbjct: 77  QTPDGSQQSPDGTQLPSGHPLPATSQGTASKCPFLAAQMNQRGSSVFCKASLELQEDVQE 136

Query: 99  F--------KTDLPSSLVSVS--------LRKPFSGPQEQEQISGKVTHLIQNNMPGNY- 141
                    +T    S+VSV         L K F     Q+Q   +V+HL+Q+N+P +  
Sbjct: 137 MNAVRKEVAETSAGPSVVSVKTDGGDPSGLLKNFQDIM-QKQRPERVSHLLQDNLPKSVS 195

Query: 142 VFSYDQFFRDKIMEKKQDHTYRVFKTVNRWADAYPFAQHFSEASVASKDVSVWCSNDYLG 201
            F YD+FF  KI EKK DHTYRVFKTVNR A  +P A  +S++ +  K VSVWCSNDYLG
Sbjct: 196 TFQYDRFFEKKIDEKKNDHTYRVFKTVNRRAHIFPMADDYSDSLITKKQVSVWCSNDYLG 255

Query: 202 MSRHPQVLQATQETLQRHGAGAGGTRNISGTSKFHVELEQELAELHQKDSALLFSSCFVA 261
           MSRHP+V  A  +TL++HGAGAGGTRNISGTSKFHV+LE+ELA+LH KD+ALLFSSCFVA
Sbjct: 256 MSRHPRVCGAVMDTLKQHGAGAGGTRNISGTSKFHVDLERELADLHGKDAALLFSSCFVA 315

Query: 262 NDSTLFTLAKILPGCEIYSDAGNHASMIQGIRNSGAAKFVFRHNDPDHLKKLLEKSNPKI 321
           NDSTLFTLAK++PGCEIYSD+GNHASMIQGIRNS   K++FRHND  HL++LL++S+P +
Sbjct: 316 NDSTLFTLAKMMPGCEIYSDSGNHASMIQGIRNSRVPKYIFRHNDVSHLRELLQRSDPSV 375

Query: 322 PKIVAFETVHSMDGAICPLEELCDVSHQYGALTFVDEVHAVGLYGSRGAGIGERDGIMHK 381
           PKIVAFETVHSMDGA+CPLEELCDV+H++GA+TFVDEVHAVGLYG+RG GIG+RDG+M K
Sbjct: 376 PKIVAFETVHSMDGAVCPLEELCDVAHEFGAITFVDEVHAVGLYGARGGGIGDRDGVMPK 435

Query: 382 IDIISGTLGKAFGCVGGYIASTRDLVDMVRSYAAGFIFTTSLPPMVLSGALESVRLLKGE 441
           +DIISGTLGKAFGCVGGYIAST  L+D VRSYAAGFIFTTSLPPM+L+GALESVR+LK  
Sbjct: 436 MDIISGTLGKAFGCVGGYIASTSSLIDTVRSYAAGFIFTTSLPPMLLAGALESVRILKSA 495

Query: 442 EGQALRRAHQRNVKHMRQLLMDRGLPVIPCPSHIIPIRVGNAALNSKLCDLLLSKHGIYV 501
           EG+ LRR HQRNVK MRQ+LMD GLPV+ CPSHIIP+RV +AA N+++CD L+S+H IYV
Sbjct: 496 EGRVLRRQHQRNVKLMRQMLMDAGLPVVHCPSHIIPVRVADAAKNTEVCDELMSRHNIYV 555

Query: 502 QAINYPTVPRGEELLRLAPSPHHSPQMMEDFVEKLLLAWTAVGLPLQDVSVAACNFCRRP 561
           QAINYPTVPRGEELLR+AP+PHH+PQMM  F+E LL+ W  VGL L+  S A CNFCRRP
Sbjct: 556 QAINYPTVPRGEELLRIAPTPHHTPQMMNYFLENLLVTWKQVGLELKPHSSAECNFCRRP 615

Query: 562 VHFELMSEWERSYFGNM 578
           +HFE+MSE E+SYF  +
Sbjct: 616 LHFEVMSEREKSYFSGL 632


>gi|7657118 glycine C-acetyltransferase precursor [Homo sapiens]
          Length = 419

 Score =  223 bits (569), Expect = 3e-58
 Identities = 131/352 (37%), Positives = 202/352 (57%), Gaps = 10/352 (2%)

Query: 194 WCSNDYLGMSRHPQVLQATQETLQRHGAGAGGTRNISGTSKFHVELEQELAELHQKDSAL 253
           +C+N+YLG+S HP+V+QA  + L+  GAG    R I GT   H  LE ++A  HQ++ A+
Sbjct: 70  FCANNYLGLSSHPEVIQAGLQALEEFGAGLSSVRFICGTQSIHKNLEAKIARFHQREDAI 129

Query: 254 LFSSCFVANDSTLFTLAKILPGCEIYSDAGNHASMIQGIRNSGAAKFVFRHNDPDHLKKL 313
           L+ SC+ AN + LF  A + P   + SD  NHAS+I GIR   A K+ +RH D   L+  
Sbjct: 130 LYPSCYDAN-AGLFE-ALLTPEDAVLSDELNHASIIDGIRLCKAHKYRYRHLDMADLEAK 187

Query: 314 LEKSNPKIPKIVAFETVHSMDGAICPLEELCDVSHQYGALTFVDEVHAVGLYGSRGAGIG 373
           L+++     ++VA +   SMDG I PL+E+C ++ +YGAL F+DE HA G  G  G G  
Sbjct: 188 LQEAQKHRLRLVATDGAFSMDGDIAPLQEICCLASRYGALVFMDECHATGFLGPTGRGTD 247

Query: 374 ERDGIMHKIDIISGTLGKAF-GCVGGYIASTRDLVDMVRSYAAGFIFTTSLPPMVLSGAL 432
           E  G+M ++ II+ TLGKA  G  GGY      LV ++R  A  ++F+ SLPP V+  A 
Sbjct: 248 ELLGVMDQVTIINSTLGKALGGASGGYTTGPGPLVSLLRQRARPYLFSNSLPPAVVGCAS 307

Query: 433 ESVRLLKGEEGQALRRAHQRNVKHMRQLLMDRGLPVIPCPSHIIPIRVGNAALNSKLCDL 492
           +++ LL G     + ++     +  R  +   G  +      I P+ +G+A L S++ D 
Sbjct: 308 KALDLLMG--SNTIVQSMAAKTQRFRSKMEAAGFTISGASHPICPVMLGDARLASRMADD 365

Query: 493 LLSKHGIYVQAINYPTVPRGEELLRLAPSPHHSPQMMEDFVEKLLLAWTAVG 544
           +L K GI+V   +YP VP+G+  +R+  S  HS    E+ +++ + A+  VG
Sbjct: 366 ML-KRGIFVIGFSYPVVPKGKARIRVQISAVHS----EEDIDRCVEAFVEVG 412


>gi|119220554 serine palmitoyltransferase, long chain base subunit 3
           [Homo sapiens]
          Length = 552

 Score =  172 bits (437), Expect = 6e-43
 Identities = 113/389 (29%), Positives = 204/389 (52%), Gaps = 21/389 (5%)

Query: 164 VFKTVNRWADAYPFAQHFSEASVASKDVSVWCSNDYLGMS-RHPQVLQATQETLQRHGAG 222
           +F  + R +D Y +   F+   +  KDV    S ++LG++ ++ + ++  ++ L+ +G G
Sbjct: 137 LFDLMERVSDDYNWTFRFTGRVI--KDVINMGSYNFLGLAAKYDESMRTIKDVLEVYGTG 194

Query: 223 AGGTRNISGTSKFHVELEQELAELHQKDSALLFSSCFVANDSTLFTLAKILPGCEIYSDA 282
              TR+  GT   H ELE  +A+    ++A++F   F  N   +  L  +  GC I SD 
Sbjct: 195 VASTRHEMGTLDKHKELEDLVAKFLNVEAAMVFGMGFATNSMNIPAL--VGKGCLILSDE 252

Query: 283 GNHASMIQGIRNSGAAKFVFRHNDPDHLKKLLEKS----NPKIPK-----IVAFETVHSM 333
            NH S++ G R SGA   +F+HN+   L+KLL  +     P+  +     ++  E V+SM
Sbjct: 253 LNHTSLVLGARLSGATIRIFKHNNTQSLEKLLRDAVIYGQPRTRRAWKKILILVEGVYSM 312

Query: 334 DGAICPLEELCDVSHQYGALTFVDEVHAVGLYGSRGAGIGERDGI-MHKIDIISGTLGKA 392
           +G+I  L ++  +  +Y A  ++DE H++G  G  G G+ E  G+  H++D++ GT  K+
Sbjct: 313 EGSIVHLPQIIALKKKYKAYLYIDEAHSIGAVGPTGRGVTEFFGLDPHEVDVLMGTFTKS 372

Query: 393 FGCVGGYIASTRDLVDMVRSYAAGFIFTTSLPPMVLSGALESVRLLKGEEG--QALRRAH 450
           FG  GGYIA  +DLVD +R ++   ++ +S+ P +    + S++L+ G +G  Q L+R  
Sbjct: 373 FGASGGYIAGRKDLVDYLRVHSHSAVYASSMSPPIAEQIIRSLKLIMGLDGTTQGLQRVQ 432

Query: 451 Q--RNVKHMRQLLMDRGLPVIPCP-SHIIPIRVGNAALNSKLCDLLLSKHGIYVQAINYP 507
           Q  +N ++ RQ L + G  +     + ++P+ +      +     +L K  I V  + +P
Sbjct: 433 QLAKNTRYFRQRLQEMGFIIYGNENASVVPLLLYMPGKVAAFARHMLEKK-IGVVVVGFP 491

Query: 508 TVPRGEELLRLAPSPHHSPQMMEDFVEKL 536
             P  E   R   S  H+ +M++  +E L
Sbjct: 492 ATPLAEARARFCVSAAHTREMLDTVLEAL 520


>gi|4758668 serine palmitoyltransferase, long chain base subunit 2
           [Homo sapiens]
          Length = 562

 Score =  154 bits (390), Expect = 2e-37
 Identities = 103/364 (28%), Positives = 183/364 (50%), Gaps = 33/364 (9%)

Query: 196 SNDYLGMSRHPQVLQ-ATQETLQRHGAGAGGTRNISGTSKFHVELEQELAELHQKDSALL 254
           S +YLG +R+    Q A  + L+ +GAG   TR   G    H ELE+ +A     ++A+ 
Sbjct: 175 SYNYLGFARNTGSCQEAAAKVLEEYGAGVCSTRQEIGNLDKHEELEELVARFLGVEAAMA 234

Query: 255 FSSCFVANDSTLFTLAKILPGCEIYSDAGNHASMIQGIRNSGAAKFVFRHNDPDHLKKLL 314
           +   F  N   +  L  +  GC I SD  NHAS++ G R SGA   +F+HN+   L+KLL
Sbjct: 235 YGMGFATNSMNIPAL--VGKGCLILSDELNHASLVLGARLSGATIRIFKHNNMQSLEKLL 292

Query: 315 EKS---------NPKIPKIVAFETVHSMDGAICPLEELCDVSHQYGALTFVDEVHAVGLY 365
           + +          P    ++  E ++SM+G+I  L E+  +  +Y A  ++DE H++G  
Sbjct: 293 KDAIVYGQPRTRRPWKKILILVEGIYSMEGSIVRLPEVIALKKKYKAYLYLDEAHSIGAL 352

Query: 366 GSRGAGIGERDGI-MHKIDIISGTLGKAFGCVGGYIASTRDLVDMVRSYAAGFIFTTSLP 424
           G  G G+ E  G+    +D++ GT  K+FG  GGYI   ++L+D +R+++   ++ TSL 
Sbjct: 353 GPTGRGVVEYFGLDPEDVDVMMGTFTKSFGASGGYIGGKKELIDYLRTHSHSAVYATSLS 412

Query: 425 PMVLSGALESVRLLKGEEGQALRR----AHQRNVKHMRQLLMDRGL--------PVIPCP 472
           P V+   + S++ + G++G +L +        N ++ R+ L + G         PV+P  
Sbjct: 413 PPVVEQIITSMKCIMGQDGTSLGKECVQQLAENTRYFRRRLKEMGFIIYGNEDSPVVPLM 472

Query: 473 SHIIPIRVGNAALNSKLCDLLLSKHGIYVQAINYPTVPRGEELLRLAPSPHHSPQMMEDF 532
            + +P ++G            + K  I V  + +P  P  E   R   S  H+ ++++  
Sbjct: 473 LY-MPAKIGAFGRE-------MLKRNIGVVVVGFPATPIIESRARFCLSAAHTKEILDTA 524

Query: 533 VEKL 536
           ++++
Sbjct: 525 LKEI 528


>gi|5454084 serine palmitoyltransferase subunit 1 isoform a [Homo
           sapiens]
          Length = 473

 Score =  123 bits (308), Expect = 5e-28
 Identities = 75/269 (27%), Positives = 142/269 (52%), Gaps = 13/269 (4%)

Query: 186 VASKDVSVWCSNDYLGMSRHPQVLQATQETLQRHGAGAGGTRNISGTSKFHVELEQELAE 245
           V  K+   + S ++LG+  +P+V  A   +L+++G G  G R   GT   H++LE  LA+
Sbjct: 95  VNGKECINFASFNFLGLLDNPRVKAAALASLKKYGVGTCGPRGFYGTFDVHLDLEDRLAK 154

Query: 246 LHQKDSALLFSSCFVANDSTLFTLAKILPGCEIYSDAGNHASMIQGIRNSGAAKFVFRHN 305
             + + A+++S  F    S +   +K   G  ++ D     ++ +G++ S +   +F+HN
Sbjct: 155 FMKTEEAIIYSYGFATIASAIPAYSK--RGDIVFVDRAACFAIQKGLQASRSDIKLFKHN 212

Query: 306 DPDHLKKLL------EKSNPKIPKI----VAFETVHSMDGAICPLEELCDVSHQYGALTF 355
           D   L++LL      ++ NP+  ++    +  E ++   G ICPL EL  + ++Y A  F
Sbjct: 213 DMADLERLLKEQEIEDQKNPRKARVTRRFIVVEGLYMNTGTICPLPELVKLKYKYKARIF 272

Query: 356 VDEVHAVGLYGSRGAGIGERDGI-MHKIDIISGTLGKAFGCVGGYIASTRDLVDMVRSYA 414
           ++E  + G+ G  G G+ E  GI +  ID+IS  +  A   +GG+      ++D  R   
Sbjct: 273 LEESLSFGVLGEHGRGVTEHYGINIDDIDLISANMENALASIGGFCCGRSFVIDHQRLSG 332

Query: 415 AGFIFTTSLPPMVLSGALESVRLLKGEEG 443
            G+ F+ SLPP++ + A+E++ +++   G
Sbjct: 333 QGYCFSASLPPLLAAAAIEALNIMEENPG 361


>gi|167000400 gamma-aminobutyric acid (GABA) B receptor 1 isoform c
           precursor [Homo sapiens]
          Length = 899

 Score = 31.2 bits (69), Expect = 2.8
 Identities = 20/79 (25%), Positives = 37/79 (46%), Gaps = 4/79 (5%)

Query: 248 QKDSALLFSSCFVANDSTLFTLAKILPGCEIYSDAGNHASMIQGIRNSGAAKFVFRHNDP 307
           Q+D+A  F+S  +   S +  +   +P        G   S  Q    +G++     +N+ 
Sbjct: 767 QQDAAFAFASLAIVFSSYITLVVLFVPKMRRLITRGEWQSEAQDTMKTGSST----NNNE 822

Query: 308 DHLKKLLEKSNPKIPKIVA 326
           +   +LLEK N ++ KI+A
Sbjct: 823 EEKSRLLEKENRELEKIIA 841


>gi|11497612 gamma-aminobutyric acid (GABA) B receptor 1 isoform b
           precursor [Homo sapiens]
          Length = 844

 Score = 31.2 bits (69), Expect = 2.8
 Identities = 20/79 (25%), Positives = 37/79 (46%), Gaps = 4/79 (5%)

Query: 248 QKDSALLFSSCFVANDSTLFTLAKILPGCEIYSDAGNHASMIQGIRNSGAAKFVFRHNDP 307
           Q+D+A  F+S  +   S +  +   +P        G   S  Q    +G++     +N+ 
Sbjct: 712 QQDAAFAFASLAIVFSSYITLVVLFVPKMRRLITRGEWQSEAQDTMKTGSST----NNNE 767

Query: 308 DHLKKLLEKSNPKIPKIVA 326
           +   +LLEK N ++ KI+A
Sbjct: 768 EEKSRLLEKENRELEKIIA 786


>gi|10835015 gamma-aminobutyric acid (GABA) B receptor 1 isoform a
           precursor [Homo sapiens]
          Length = 961

 Score = 31.2 bits (69), Expect = 2.8
 Identities = 20/79 (25%), Positives = 37/79 (46%), Gaps = 4/79 (5%)

Query: 248 QKDSALLFSSCFVANDSTLFTLAKILPGCEIYSDAGNHASMIQGIRNSGAAKFVFRHNDP 307
           Q+D+A  F+S  +   S +  +   +P        G   S  Q    +G++     +N+ 
Sbjct: 829 QQDAAFAFASLAIVFSSYITLVVLFVPKMRRLITRGEWQSEAQDTMKTGSST----NNNE 884

Query: 308 DHLKKLLEKSNPKIPKIVA 326
           +   +LLEK N ++ KI+A
Sbjct: 885 EEKSRLLEKENRELEKIIA 903


>gi|66529005 ATP-binding cassette, sub-family C, member 5 isoform 1
           [Homo sapiens]
          Length = 1437

 Score = 30.8 bits (68), Expect = 3.6
 Identities = 18/62 (29%), Positives = 28/62 (45%)

Query: 440 GEEGQALRRAHQRNVKHMRQLLMDRGLPVIPCPSHIIPIRVGNAALNSKLCDLLLSKHGI 499
           GE G  L    ++ +   R L  DR + ++  P   +   VGN   NS +   L SK  +
Sbjct: 679 GERGANLSGGQRQRISLARALYSDRSIYILDDPLSALDAHVGNHIFNSAIRKHLKSKTVL 738

Query: 500 YV 501
           +V
Sbjct: 739 FV 740


>gi|30474871 serine palmitoyltransferase subunit 1 isoform b [Homo
           sapiens]
          Length = 143

 Score = 30.0 bits (66), Expect = 6.2
 Identities = 15/47 (31%), Positives = 26/47 (55%)

Query: 186 VASKDVSVWCSNDYLGMSRHPQVLQATQETLQRHGAGAGGTRNISGT 232
           V  K+   + S ++LG+  +P+V  A   +L+++G G  G R   GT
Sbjct: 95  VNGKECINFASFNFLGLLDNPRVKAAALASLKKYGVGTCGPRGFYGT 141


>gi|41872631 fatty acid synthase [Homo sapiens]
          Length = 2511

 Score = 29.6 bits (65), Expect = 8.1
 Identities = 12/26 (46%), Positives = 14/26 (53%)

Query: 199  YLGMSRHPQVLQATQETLQRHGAGAG 224
            Y    RHPQ L+A Q  LQ+H    G
Sbjct: 1270 YTATDRHPQALEAAQAELQQHDVAQG 1295


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.135    0.411 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,907,546
Number of Sequences: 37866
Number of extensions: 1029603
Number of successful extensions: 2304
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 2274
Number of HSP's gapped (non-prelim): 17
length of query: 587
length of database: 18,247,518
effective HSP length: 108
effective length of query: 479
effective length of database: 14,157,990
effective search space: 6781677210
effective search space used: 6781677210
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.