Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 81158224
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|81158224 neuronal cell adhesion molecule isoform B precursor
[Homo sapiens]
(1183 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|81158224 neuronal cell adhesion molecule isoform B precursor ... 2409 0.0
gi|81158226 neuronal cell adhesion molecule isoform A precursor ... 2096 0.0
gi|89903008 neurofascin isoform 4 precursor [Homo sapiens] 1235 0.0
gi|237858679 neurofascin isoform 3 precursor [Homo sapiens] 1229 0.0
gi|237858677 neurofascin isoform 2 precursor [Homo sapiens] 1219 0.0
gi|237858675 neurofascin isoform 1 precursor [Homo sapiens] 1047 0.0
gi|27894376 cell adhesion molecule with homology to L1CAM precur... 875 0.0
gi|221316760 L1 cell adhesion molecule isoform 3 precursor [Homo... 770 0.0
gi|13435353 L1 cell adhesion molecule isoform 2 precursor [Homo ... 763 0.0
gi|4557707 L1 cell adhesion molecule isoform 1 precursor [Homo s... 763 0.0
gi|237858682 neurofascin isoform 6 precursor [Homo sapiens] 667 0.0
gi|237858680 neurofascin isoform 5 precursor [Homo sapiens] 660 0.0
gi|4827022 contactin 2 precursor [Homo sapiens] 376 e-104
gi|75709184 contactin 3 [Homo sapiens] 374 e-103
gi|7657359 contactin 5 isoform long [Homo sapiens] 362 1e-99
gi|28373129 contactin 5 isoform short [Homo sapiens] 362 1e-99
gi|28373122 contactin 4 isoform a precursor [Homo sapiens] 358 2e-98
gi|7657361 contactin 6 [Homo sapiens] 337 3e-92
gi|28373117 contactin 1 isoform 1 precursor [Homo sapiens] 312 1e-84
gi|28373119 contactin 1 isoform 2 precursor [Homo sapiens] 312 1e-84
gi|28373126 contactin 4 isoform c precursor [Homo sapiens] 269 1e-71
gi|222352127 sidekick 2 [Homo sapiens] 264 4e-70
gi|119220552 sidekick 1 [Homo sapiens] 261 2e-69
gi|20127422 Down syndrome cell adhesion molecule isoform CHD2-42... 229 2e-59
gi|21359935 Down syndrome cell adhesion molecule like 1 [Homo sa... 229 2e-59
gi|157311649 neogenin homolog 1 [Homo sapiens] 226 1e-58
gi|110431348 deleted in colorectal carcinoma [Homo sapiens] 213 7e-55
gi|109633041 protein tyrosine phosphatase, receptor type, F isof... 201 4e-51
gi|109633039 protein tyrosine phosphatase, receptor type, F isof... 201 4e-51
gi|118572606 hemicentin 1 [Homo sapiens] 197 5e-50
>gi|81158224 neuronal cell adhesion molecule isoform B precursor [Homo
sapiens]
Length = 1183
Score = 2409 bits (6244), Expect = 0.0
Identities = 1183/1183 (100%), Positives = 1183/1183 (100%)
Query: 1 MQLKIMPKKKRLSAGRVPLILFLCQMISALEVPLDLVQPPTITQQSPKDYIIDPRENIVI 60
MQLKIMPKKKRLSAGRVPLILFLCQMISALEVPLDLVQPPTITQQSPKDYIIDPRENIVI
Sbjct: 1 MQLKIMPKKKRLSAGRVPLILFLCQMISALEVPLDLVQPPTITQQSPKDYIIDPRENIVI 60
Query: 61 QCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQCTAR 120
QCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQCTAR
Sbjct: 61 QCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQCTAR 120
Query: 121 NERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQ 180
NERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQ
Sbjct: 121 NERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQ 180
Query: 181 RLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELND 240
RLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELND
Sbjct: 181 RLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELND 240
Query: 241 TIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAK 300
TIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAK
Sbjct: 241 TIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAK 300
Query: 301 EDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITA 360
EDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITA
Sbjct: 301 EDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITA 360
Query: 361 PQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERS 420
PQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERS
Sbjct: 361 PQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERS 420
Query: 421 SAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTI 480
SAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTI
Sbjct: 421 SAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTI 480
Query: 481 EWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPT 540
EWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPT
Sbjct: 481 EWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPT 540
Query: 541 WIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVADV 600
WIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVADV
Sbjct: 541 WIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVADV 600
Query: 601 SDDDSGTYTCVANTTLDSVSASAVLSVVDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSP 660
SDDDSGTYTCVANTTLDSVSASAVLSVVDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSP
Sbjct: 601 SDDDSGTYTCVANTTLDSVSASAVLSVVDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSP 660
Query: 661 ITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEAS 720
ITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEAS
Sbjct: 661 ITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEAS 720
Query: 721 EQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDEWT 780
EQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDEWT
Sbjct: 721 EQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDEWT 780
Query: 781 SVVVANVSKYIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNV 840
SVVVANVSKYIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNV
Sbjct: 781 SVVVANVSKYIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNV 840
Query: 841 VNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLP 900
VNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLP
Sbjct: 841 VNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLP 900
Query: 901 GLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDPPS 960
GLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDPPS
Sbjct: 901 GLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDPPS 960
Query: 961 HPNGILTEYTLKYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGS 1020
HPNGILTEYTLKYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGS
Sbjct: 961 HPNGILTEYTLKYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGS 1020
Query: 1021 GSQITEEAVTTVDEAMASRQVDIATQGWFIGLMCAVALLILILLIVCFIRRNKGGKYPVK 1080
GSQITEEAVTTVDEAMASRQVDIATQGWFIGLMCAVALLILILLIVCFIRRNKGGKYPVK
Sbjct: 1021 GSQITEEAVTTVDEAMASRQVDIATQGWFIGLMCAVALLILILLIVCFIRRNKGGKYPVK 1080
Query: 1081 EKEDAHADPEIQPMKEDDGTFGEYSDAEDHKPLKKGSRTPSDRTVKKEDSDDSLVDYGEG 1140
EKEDAHADPEIQPMKEDDGTFGEYSDAEDHKPLKKGSRTPSDRTVKKEDSDDSLVDYGEG
Sbjct: 1081 EKEDAHADPEIQPMKEDDGTFGEYSDAEDHKPLKKGSRTPSDRTVKKEDSDDSLVDYGEG 1140
Query: 1141 VNGQFNEDGSFIGQYSGKKEKEPAEGNESSEAPSPVNAMNSFV 1183
VNGQFNEDGSFIGQYSGKKEKEPAEGNESSEAPSPVNAMNSFV
Sbjct: 1141 VNGQFNEDGSFIGQYSGKKEKEPAEGNESSEAPSPVNAMNSFV 1183
>gi|81158226 neuronal cell adhesion molecule isoform A precursor [Homo
sapiens]
Length = 1304
Score = 2096 bits (5430), Expect = 0.0
Identities = 1035/1051 (98%), Positives = 1035/1051 (98%), Gaps = 16/1051 (1%)
Query: 1 MQLKIMPKKKRLSAGRVPLILFLCQMISALEVPLD------LVQPPTITQQSPKDYIIDP 54
MQLKIMPKKKRLSAGRVPLILFLCQMISALEVPLD LVQPPTITQQSPKDYIIDP
Sbjct: 1 MQLKIMPKKKRLSAGRVPLILFLCQMISALEVPLDPKLLEDLVQPPTITQQSPKDYIIDP 60
Query: 55 RENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGV 114
RENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGV
Sbjct: 61 RENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGV 120
Query: 115 YQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFW 174
YQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFW
Sbjct: 121 YQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFW 180
Query: 175 MDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVIS 234
MDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVIS
Sbjct: 181 MDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVIS 240
Query: 235 VDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTP 294
VDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTP
Sbjct: 241 VDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTP 300
Query: 295 IIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAA 354
IIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAA
Sbjct: 301 IIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAA 360
Query: 355 PYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFS 414
PYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFS
Sbjct: 361 PYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFS 420
Query: 415 NVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFG 474
NVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFG
Sbjct: 421 NVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFG 480
Query: 475 SPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHL 534
SPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHL
Sbjct: 481 SPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHL 540
Query: 535 EIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH 594
EIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH
Sbjct: 541 EIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH 600
Query: 595 LVVADVSDDDSGTYTCVANTTLDSVSASAVLSVV----------DVPNPPFDLELTDQLD 644
LVVADVSDDDSGTYTCVANTTLDSVSASAVLSVV DVPNPPFDLELTDQLD
Sbjct: 601 LVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAPTPTPAPVYDVPNPPFDLELTDQLD 660
Query: 645 KSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFR 704
KSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFR
Sbjct: 661 KSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFR 720
Query: 705 VMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGL 764
VMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGL
Sbjct: 721 VMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGL 780
Query: 765 QYKVSWRQKDGDDEWTSVVVANVSKYIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHS 824
QYKVSWRQKDGDDEWTSVVVANVSKYIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHS
Sbjct: 781 QYKVSWRQKDGDDEWTSVVVANVSKYIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHS 840
Query: 825 GEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIE 884
GEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIE
Sbjct: 841 GEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIE 900
Query: 885 KKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPSAPSSLKI 944
KKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPSAPSSLKI
Sbjct: 901 KKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPSAPSSLKI 960
Query: 945 VNPTLDSLTLEWDPPSHPNGILTEYTLKYQPINSTHELGPLVDLKIPANKTRWTLKNLNF 1004
VNPTLDSLTLEWDPPSHPNGILTEYTLKYQPINSTHELGPLVDLKIPANKTRWTLKNLNF
Sbjct: 961 VNPTLDSLTLEWDPPSHPNGILTEYTLKYQPINSTHELGPLVDLKIPANKTRWTLKNLNF 1020
Query: 1005 STRYKFYFYAQTSAGSGSQITEEAVTTVDEA 1035
STRYKFYFYAQTSAGSGSQITEEAVTTVDEA
Sbjct: 1021 STRYKFYFYAQTSAGSGSQITEEAVTTVDEA 1051
Score = 363 bits (933), Expect = e-100
Identities = 341/1090 (31%), Positives = 470/1090 (43%), Gaps = 130/1090 (11%)
Query: 154 GQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICY 213
G L L C GLP PII+W LP++ V + L +V D+ +Y C
Sbjct: 285 GNVLSLECIAE-GLPTPIIYWAKEDGM-LPKNRTVYKNFEKTLQIIHVSEADSG-NYQCI 341
Query: 214 ARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASN 273
A+ N I + VK P ++T N
Sbjct: 342 AK-NALGAIHHTISVRVKAA----------------------------PYWITAPQNLVL 372
Query: 274 KEELRGNVLSLECIAEGLPTPIIYWAKEDGM---LPKNRTVYKNFEKTLQIIHVSEADSG 330
G ++ C A G P P I W +G+ + + K T+ +V E S
Sbjct: 373 SPGEDGTLI---CRANGNPKPRISWLT-NGVPIEIAPDDPSRKIDGDTIIFSNVQERSSA 428
Query: 331 NYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLS--PGEDGTLICRANGNPKPRISW 388
YQC A N G + V V A P I P N + L C G+P P I W
Sbjct: 429 VYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEW 488
Query: 389 LTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPP 448
G +D + T+ Q+ S+ Y C A N+ G +A V++ + P
Sbjct: 489 F-KGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLG--MAKNEVHLEIKDP 545
Query: 449 RILTPANTLYQVIANRPALLDCAFFGSPLP--TIEWFKGAKGSALHEDIYVLHENGTLEI 506
+ V +C T+ W K + E V + L +
Sbjct: 546 TWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTV--DKDHLVV 603
Query: 507 PVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFECKVKHD 566
D +GTYTCVA L L + PT P A V F+ ++
Sbjct: 604 ADVSDDDSGTYTCVANTTLDSVSASAVLSVVAPT-----PTPAPVYDVPNPPFDLELTDQ 658
Query: 567 HTLSLTVLWLKDNRELPSDERFTVDKDHLV----VADVSDDDSGTYTCVA---------- 612
S+ + W + +F ++ + + + + SGT T
Sbjct: 659 LDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYS 718
Query: 613 ---------NTTLDSVSASAVLSVVDVPNP-PFDLELTDQLDKSVQLSWTP--GDDNNSP 660
+L S ++ L+ P+ P +E ++ ++W P G ++N P
Sbjct: 719 FRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGP 778
Query: 661 ITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSP-YVNYSFRVMAVNSIGKSLPSEA 719
++ + + K G + V + + +P +V Y +V A+N +G + P A
Sbjct: 779 GLQYKVSWRQ---KDGDDEWTSVVVANVSKYIVSGTPTFVPYLIKVQALNDMGFA-PEPA 834
Query: 720 SEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVS-WRQKDGDDE 778
+ P P V + W P+ G Y++ W+ +
Sbjct: 835 VVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKR 894
Query: 779 WTSVVVANVSKY-------IVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMV 831
+ + + ++ G F Y + V+ +N G P + ++ E +P
Sbjct: 895 NRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPS- 953
Query: 832 APGNVRVNVVNSTLAEV--HWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILT 889
AP ++++ VN TL + WDP + G L Y + Y S+ + ++ KI
Sbjct: 954 APSSLKI--VNPTLDSLTLEWDPPSHPN--GILTEYTLKYQPINSTHELGPL-VDLKI-- 1006
Query: 890 FQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPSAP-----SSLKI 944
+KT L L + Y G G + T + P ++
Sbjct: 1007 -PANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEEAVTTVDEAGILPPDVGAGKVQA 1065
Query: 945 VNPTLDSLTL-----------EWDPPSHPNGILTEYTLKYQPINSTHELGPLVDLKIPAN 993
VNP + +LT E++ P H N + ++Y S E + + +
Sbjct: 1066 VNPRISNLTAAAAETYANISWEYEGPEHVN-----FYVEYGVAGSKEEWRKEI---VNGS 1117
Query: 994 KTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEEAVTTVDEAMASRQVDIATQGWFIGLM 1053
++ + LK L T YK A G ++ E V AMASRQVDIATQGWFIGLM
Sbjct: 1118 RSFFGLKGLMPGTAYKVRVGA---VGDSGFVSSEDVFETGPAMASRQVDIATQGWFIGLM 1174
Query: 1054 CAVALLILILLIVCFIRRNKGGKYPVKEKEDAHADPEIQPMKEDDGTFGEYSDAEDHKPL 1113
CAVALLILILLIVCFIRRNKGGKYPVKEKEDAHADPEIQPMKEDDGTFGEYSDAEDHKPL
Sbjct: 1175 CAVALLILILLIVCFIRRNKGGKYPVKEKEDAHADPEIQPMKEDDGTFGEYSDAEDHKPL 1234
Query: 1114 KKGSRTPSDRTVKKEDSDDSLVDYGEGVNGQFNEDGSFIGQYSGKKEKEPAEGNESSEAP 1173
KKGSRTPSDRTVKKEDSDDSLVDYGEGVNGQFNEDGSFIGQYSGKKEKEPAEGNESSEAP
Sbjct: 1235 KKGSRTPSDRTVKKEDSDDSLVDYGEGVNGQFNEDGSFIGQYSGKKEKEPAEGNESSEAP 1294
Query: 1174 SPVNAMNSFV 1183
SPVNAMNSFV
Sbjct: 1295 SPVNAMNSFV 1304
>gi|89903008 neurofascin isoform 4 precursor [Homo sapiens]
Length = 1169
Score = 1235 bits (3195), Expect = 0.0
Identities = 607/1162 (52%), Positives = 815/1162 (70%), Gaps = 9/1162 (0%)
Query: 20 ILFLCQMISALEVPLDLVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGT 79
+L L + A+E+P+DL QPPTIT+QS KD+I+DPR+NI+I+CEAKG P PSF WTRN
Sbjct: 15 LLCLLSLGGAIEIPMDLTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSR 74
Query: 80 HFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSP 139
F+I KDP V+M+ +GTL+I+ S G+ E YEG YQC ARN+ G A+SN I ++ S+SP
Sbjct: 75 FFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSP 134
Query: 140 LWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFS 199
LW KE L+P+ +Q G L L C PP GLP P+IFWM +S + + Q +RVSQG NGDLYFS
Sbjct: 135 LWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFS 194
Query: 200 NVLPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRE 259
NV+ +D + DY C ARF+ T TIQQK P ++KV++ ND+ N D Y A+ E
Sbjct: 195 NVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRNHPD--MYSARGVAE 252
Query: 260 RPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTL 319
R P+F+ P+G AS++ LRG L LECIA G+PTP I W K+ G LP ++ ++NF K L
Sbjct: 253 RTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKAL 312
Query: 320 QIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRAN 379
+I +VSE DSG Y C+A N +G+I HTISVRVKAAPYW+ P+NL+L+PGEDG L+CRAN
Sbjct: 313 RITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRAN 372
Query: 380 GNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANA 439
GNPKP + W+ NG P++ AP +P+R++ GDTIIF + Q S AVYQCN SNE+GYLLANA
Sbjct: 373 GNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANA 432
Query: 440 FVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLH 499
FV+VL PPR+L+P N L +VI LDC FFGSP+PT+ WFK +GS L Y ++
Sbjct: 433 FVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVY 492
Query: 500 ENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSF 559
ENG+LEI + +K+ G YTCVA N LG A+N+V LE+KDPT I + PE V +RG+ V
Sbjct: 493 ENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQL 552
Query: 560 ECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVADVSDDDSGTYTCVANTTLDSV 619
EC+VKHD +L LTV WLKD+ L R + D L + V++ D G+YTCVA+T LD
Sbjct: 553 ECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVAERDQGSYTCVASTELDQD 612
Query: 620 SASAVLSVVDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWH 679
A A L+V+ P+ P DLELTD ++SV+L+W PGD NNSPIT +++++E+ +PG+WH
Sbjct: 613 LAKAYLTVLGRPDRPRDLELTDLAERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWH 672
Query: 680 HQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEG 739
++ G+ +A L+LSPYVNY FRV+A+N +G S PS SE+Y T + P+ NP V+G
Sbjct: 673 DHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKG 732
Query: 740 LGSEPDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDEWTSVVVANVSKYIVSGTPTFV 799
G+ +N+ ITW P+N + GP L+Y V WR+++ + W +V V S+Y+V TP +V
Sbjct: 733 EGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETREAWNNVTVWG-SRYVVGQTPVYV 791
Query: 800 PYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIR 859
PY I+VQA ND G PEP V+G+SGED P AP V+V V+NST + W+ V +++
Sbjct: 792 PYEIRVQAENDFGKGPEPESVIGYSGEDYPRAAPTEVKVRVMNSTAISLQWNRVYSDTVQ 851
Query: 860 GHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKG 919
G L+ YR YYW+ S K +++ +F G + G++ L P+S+Y L + VVNG+G
Sbjct: 852 GQLREYRAYYWRESSLLKNLWVSQKRQQASFPGDRLRGVVSRLFPYSNYKLEMVVVNGRG 911
Query: 920 EGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDPPSHPNGILTEYTLKYQPINST 979
+GP S + F TPEGVPSAP ++ P L+++ LEWD P HPNGI+ YTLKY N T
Sbjct: 912 DGPRSETKEFTTPEGVPSAPRRFRVRQPNLETINLEWDHPEHPNGIMIGYTLKYVAFNGT 971
Query: 980 HELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEEAVTTVDEAMASR 1039
++G + N+T++T++ + +RY+F A+T GSG +TEE+ +EA +
Sbjct: 972 -KVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEAVTEESPAPPNEAYTNN 1030
Query: 1040 QVDIATQGWFIGLMCAVALLILILLIVCFIRRNKGGKYPVKEKEDAHADPEIQPMKEDDG 1099
Q DIATQGWFIGLMCA+ALL+LILLIVCFI+R++GGKYPV+EK+D PE KE+DG
Sbjct: 1031 QADIATQGWFIGLMCAIALLVLILLIVCFIKRSRGGKYPVREKKDVPLGPE--DPKEEDG 1088
Query: 1100 TFGEYSDAEDHKPLKKGSRTPSDRTVKKEDSDDSLVDYGEGVNGQFNEDGSFIGQYSGKK 1159
+F +YSD ED+KPL +GS+T D T+K+++SDDSLVDYGEG GQFNEDGSFIGQY+ KK
Sbjct: 1089 SF-DYSD-EDNKPL-QGSQTSLDGTIKQQESDDSLVDYGEGGEGQFNEDGSFIGQYTVKK 1145
Query: 1160 EKEPAEGNESSEAPSPVNAMNS 1181
+KE EGNESSEA SPVNA+ S
Sbjct: 1146 DKEETEGNESSEATSPVNAIYS 1167
>gi|237858679 neurofascin isoform 3 precursor [Homo sapiens]
Length = 1174
Score = 1229 bits (3179), Expect = 0.0
Identities = 607/1167 (52%), Positives = 815/1167 (69%), Gaps = 14/1167 (1%)
Query: 20 ILFLCQMISALEVPLDLVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGT 79
+L L + A+E+P+DL QPPTIT+QS KD+I+DPR+NI+I+CEAKG P PSF WTRN
Sbjct: 15 LLCLLSLGGAIEIPMDLTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSR 74
Query: 80 HFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSP 139
F+I KDP V+M+ +GTL+I+ S G+ E YEG YQC ARN+ G A+SN I ++ S+SP
Sbjct: 75 FFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSP 134
Query: 140 LWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFS 199
LW KE L+P+ +Q G L L C PP GLP P+IFWM +S + + Q +RVSQG NGDLYFS
Sbjct: 135 LWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFS 194
Query: 200 NVLPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRE 259
NV+ +D + DY C ARF+ T TIQQK P ++KV++ ND+ N D Y A+ E
Sbjct: 195 NVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRNHPD--MYSARGVAE 252
Query: 260 RPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTL 319
R P+F+ P+G AS++ LRG L LECIA G+PTP I W K+ G LP ++ ++NF K L
Sbjct: 253 RTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKAL 312
Query: 320 QIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRAN 379
+I +VSE DSG Y C+A N +G+I HTISVRVKAAPYW+ P+NL+L+PGEDG L+CRAN
Sbjct: 313 RITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRAN 372
Query: 380 GNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANA 439
GNPKP + W+ NG P++ AP +P+R++ GDTIIF + Q S AVYQCN SNE+GYLLANA
Sbjct: 373 GNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANA 432
Query: 440 FVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLH 499
FV+VL PPR+L+P N L +VI LDC FFGSP+PT+ WFK +GS L Y ++
Sbjct: 433 FVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVY 492
Query: 500 ENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSF 559
ENG+LEI + +K+ G YTCVA N LG A+N+V LE+KDPT I + PE V +RG+ V
Sbjct: 493 ENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQL 552
Query: 560 ECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVADVSDDDSGTYTCVANTTLDSV 619
EC+VKHD +L LTV WLKD+ L R + D L + V++ D G+YTCVA+T LD
Sbjct: 553 ECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVAERDQGSYTCVASTELDQD 612
Query: 620 SASAVLSVVDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWH 679
A A L+V+ P+ P DLELTD ++SV+L+W PGD NNSPIT +++++E+ +PG+WH
Sbjct: 613 LAKAYLTVLGRPDRPRDLELTDLAERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWH 672
Query: 680 HQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEG 739
++ G+ +A L+LSPYVNY FRV+A+N +G S PS SE+Y T + P+ NP V+G
Sbjct: 673 DHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKG 732
Query: 740 LGSEPDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDEWTSVVVANVSKYIVSGTPTFV 799
G+ +N+ ITW P+N + GP L+Y V WR+++ + W +V V S+Y+V TP +V
Sbjct: 733 EGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETREAWNNVTVWG-SRYVVGQTPVYV 791
Query: 800 PYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIR 859
PY I+VQA ND G PEP V+G+SGED P AP V+V V+NST + W+ V +++
Sbjct: 792 PYEIRVQAENDFGKGPEPESVIGYSGEDYPRAAPTEVKVRVMNSTAISLQWNRVYSDTVQ 851
Query: 860 GHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKG 919
G L+ YR YYW+ S K +++ +F G + G++ L P+S+Y L + VVNG+G
Sbjct: 852 GQLREYRAYYWRESSLLKNLWVSQKRQQASFPGDRLRGVVSRLFPYSNYKLEMVVVNGRG 911
Query: 920 EGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDPPSHPNGILTEYTLKYQPINST 979
+GP S + F TPEGVPSAP ++ P L+++ LEWD P HPNGI+ YTLKY N T
Sbjct: 912 DGPRSETKEFTTPEGVPSAPRRFRVRQPNLETINLEWDHPEHPNGIMIGYTLKYVAFNGT 971
Query: 980 HELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEEAVTTVDE----- 1034
++G + N+T++T++ + +RY+F A+T GSG +TEE+ +E
Sbjct: 972 -KVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEAVTEESPAPPNEATPTA 1030
Query: 1035 AMASRQVDIATQGWFIGLMCAVALLILILLIVCFIRRNKGGKYPVKEKEDAHADPEIQPM 1094
A + Q DIATQGWFIGLMCA+ALL+LILLIVCFI+R++GGKYPV+EK+D PE
Sbjct: 1031 AYTNNQADIATQGWFIGLMCAIALLVLILLIVCFIKRSRGGKYPVREKKDVPLGPE--DP 1088
Query: 1095 KEDDGTFGEYSDAEDHKPLKKGSRTPSDRTVKKEDSDDSLVDYGEGVNGQFNEDGSFIGQ 1154
KE+DG+F +YSD ED+KPL +GS+T D T+K+++SDDSLVDYGEG GQFNEDGSFIGQ
Sbjct: 1089 KEEDGSF-DYSD-EDNKPL-QGSQTSLDGTIKQQESDDSLVDYGEGGEGQFNEDGSFIGQ 1145
Query: 1155 YSGKKEKEPAEGNESSEAPSPVNAMNS 1181
Y+ KK+KE EGNESSEA SPVNA+ S
Sbjct: 1146 YTVKKDKEETEGNESSEATSPVNAIYS 1172
>gi|237858677 neurofascin isoform 2 precursor [Homo sapiens]
Length = 1189
Score = 1219 bits (3153), Expect = 0.0
Identities = 607/1182 (51%), Positives = 815/1182 (68%), Gaps = 29/1182 (2%)
Query: 20 ILFLCQMISALEVPLDLVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGT 79
+L L + A+E+P+DL QPPTIT+QS KD+I+DPR+NI+I+CEAKG P PSF WTRN
Sbjct: 15 LLCLLSLGGAIEIPMDLTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSR 74
Query: 80 HFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSP 139
F+I KDP V+M+ +GTL+I+ S G+ E YEG YQC ARN+ G A+SN I ++ S+SP
Sbjct: 75 FFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSP 134
Query: 140 LWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFS 199
LW KE L+P+ +Q G L L C PP GLP P+IFWM +S + + Q +RVSQG NGDLYFS
Sbjct: 135 LWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFS 194
Query: 200 NVLPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRE 259
NV+ +D + DY C ARF+ T TIQQK P ++KV++ ND+ N D Y A+ E
Sbjct: 195 NVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRNHPD--MYSARGVAE 252
Query: 260 RPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTL 319
R P+F+ P+G AS++ LRG L LECIA G+PTP I W K+ G LP ++ ++NF K L
Sbjct: 253 RTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKAL 312
Query: 320 QIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRAN 379
+I +VSE DSG Y C+A N +G+I HTISVRVKAAPYW+ P+NL+L+PGEDG L+CRAN
Sbjct: 313 RITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRAN 372
Query: 380 GNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANA 439
GNPKP + W+ NG P++ AP +P+R++ GDTIIF + Q S AVYQCN SNE+GYLLANA
Sbjct: 373 GNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANA 432
Query: 440 FVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLH 499
FV+VL PPR+L+P N L +VI LDC FFGSP+PT+ WFK +GS L Y ++
Sbjct: 433 FVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVY 492
Query: 500 ENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSF 559
ENG+LEI + +K+ G YTCVA N LG A+N+V LE+KDPT I + PE V +RG+ V
Sbjct: 493 ENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQL 552
Query: 560 ECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVADVSDDDSGTYTCVANTTLDSV 619
EC+VKHD +L LTV WLKD+ L R + D L + V++ D G+YTCVA+T LD
Sbjct: 553 ECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVAERDQGSYTCVASTELDQD 612
Query: 620 SASAVLSVV---------------DVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKF 664
A A L+V+ P+ P DLELTD ++SV+L+W PGD NNSPIT +
Sbjct: 613 LAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLAERSVRLTWIPGDANNSPITDY 672
Query: 665 IIEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEASEQYL 724
++++E+ +PG+WH ++ G+ +A L+LSPYVNY FRV+A+N +G S PS SE+Y
Sbjct: 673 VVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHPSLPSERYR 732
Query: 725 TKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDEWTSVVV 784
T + P+ NP V+G G+ +N+ ITW P+N + GP L+Y V WR+++ + W +V V
Sbjct: 733 TSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETREAWNNVTV 792
Query: 785 ANVSKYIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNST 844
S+Y+V TP +VPY I+VQA ND G PEP V+G+SGED P AP V+V V+NST
Sbjct: 793 WG-SRYVVGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGEDYPRAAPTEVKVRVMNST 851
Query: 845 LAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEP 904
+ W+ V +++G L+ YR YYW+ S K +++ +F G + G++ L P
Sbjct: 852 AISLQWNRVYSDTVQGQLREYRAYYWRESSLLKNLWVSQKRQQASFPGDRLRGVVSRLFP 911
Query: 905 FSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDPPSHPNG 964
+S+Y L + VVNG+G+GP S + F TPEGVPSAP ++ P L+++ LEWD P HPNG
Sbjct: 912 YSNYKLEMVVVNGRGDGPRSETKEFTTPEGVPSAPRRFRVRQPNLETINLEWDHPEHPNG 971
Query: 965 ILTEYTLKYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQI 1024
I+ YTLKY N T ++G + N+T++T++ + +RY+F A+T GSG +
Sbjct: 972 IMIGYTLKYVAFNGT-KVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEAV 1030
Query: 1025 TEEAVTTVDE-----AMASRQVDIATQGWFIGLMCAVALLILILLIVCFIRRNKGGKYPV 1079
TEE+ +E A + Q DIATQGWFIGLMCA+ALL+LILLIVCFI+R++GGKYPV
Sbjct: 1031 TEESPAPPNEATPTAAYTNNQADIATQGWFIGLMCAIALLVLILLIVCFIKRSRGGKYPV 1090
Query: 1080 KEKEDAHADPEIQPMKEDDGTFGEYSDAEDHKPLKKGSRTPSDRTVKKEDSDDSLVDYGE 1139
+EK+D PE KE+DG+F +YSD ED+KPL +GS+T D T+K+++SDDSLVDYGE
Sbjct: 1091 REKKDVPLGPE--DPKEEDGSF-DYSD-EDNKPL-QGSQTSLDGTIKQQESDDSLVDYGE 1145
Query: 1140 GVNGQFNEDGSFIGQYSGKKEKEPAEGNESSEAPSPVNAMNS 1181
G GQFNEDGSFIGQY+ KK+KE EGNESSEA SPVNA+ S
Sbjct: 1146 GGEGQFNEDGSFIGQYTVKKDKEETEGNESSEATSPVNAIYS 1187
>gi|237858675 neurofascin isoform 1 precursor [Homo sapiens]
Length = 1240
Score = 1047 bits (2707), Expect = 0.0
Identities = 576/1262 (45%), Positives = 771/1262 (61%), Gaps = 138/1262 (10%)
Query: 20 ILFLCQMISALEVPLD------LVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFS 73
+L L + A+E+P+D L QPPTIT+QS KD+I+DPR+NI+I+CEAKG P PSF
Sbjct: 15 LLCLLSLGGAIEIPMDPSIQNELTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFH 74
Query: 74 WTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVV 133
WTRN F+I KDP V+M+ +GTL+I+ S G+ E YEG YQC ARN+ G A+SN I +
Sbjct: 75 WTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRL 134
Query: 134 RPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLN 193
+ S+SPLW KE L+P+ +Q G L L C PP GLP P+IFWM +S + + Q +RVSQG N
Sbjct: 135 QVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHN 194
Query: 194 GDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYG 253
GDLYFSNV+ +D + DY C ARF+ T TIQQK P ++KV++
Sbjct: 195 GDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTT------------------ 236
Query: 254 AKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYK 313
+ ER P+F+ P+G AS++ LRG L LECIA G+PTP I W K+ G LP ++ ++
Sbjct: 237 -RGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFE 295
Query: 314 NFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGT 373
NF K L+I +VSE DSG Y C+A N +G+I HTISVRVKAAPYW+ P+NL+L+PGEDG
Sbjct: 296 NFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGR 355
Query: 374 LICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYG 433
L+CRANGNPKP + W+ NG P++ AP +P+R++ GDTIIF + Q S AVYQCN SNE+G
Sbjct: 356 LVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHG 415
Query: 434 YLLANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHE 493
YLLANAFV+VL PPR+L+P N L +VI LDC FFGSP+PT+ WFK +GS L
Sbjct: 416 YLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDG 475
Query: 494 DIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQR 553
Y ++ENG+LEI + +K+ G YTCVA N LG A+N+V LE+KDPT I + PE V +R
Sbjct: 476 GNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARR 535
Query: 554 GSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVADVSDDDSGTYTCVAN 613
G+ V EC+VKHD +L LTV WLKD+ L R + D L + V++ D G+YTCVA+
Sbjct: 536 GTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVAERDQGSYTCVAS 595
Query: 614 TTLDSVSASAVLSVV---------------DVPNPPFDLELTDQLDKSVQLSWTPGDDNN 658
T LD A A L+V+ P+ P DLELTD ++SV+L+W PGD NN
Sbjct: 596 TELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLAERSVRLTWIPGDANN 655
Query: 659 SPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSE 718
SPIT +++++E+ +PG+WH ++ G+ +A L+LSPYVNY FRV+A+N +G S PS
Sbjct: 656 SPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHPSL 715
Query: 719 ASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDE 778
SE+Y T + P+ NP V+G G+ +N+ ITW P+N + GP L+Y V WR+++ +
Sbjct: 716 PSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETREA 775
Query: 779 WTSVVVANVSKYIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRV 838
W +V V S+Y+V TP +VPY I+VQA ND G PEP V+G+SGEDLP AP RV
Sbjct: 776 WNNVTVWG-SRYVVGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGEDLPS-APRRFRV 833
Query: 839 NVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGM 898
N + WD + G + GY + Y + +K ++ +E F ++T
Sbjct: 834 RQPNLETINLEWDHP--EHPNGIMIGYTLKY-VAFNGTKVGKQIVE----NFSPNQTKFT 886
Query: 899 LPGLEPFSHY--TLNVRVVNGKG-----EGPASPDRVFNTPEGVPS-------------A 938
+ +P S Y TL+ R G G E PA P+ TP P +
Sbjct: 887 VQRTDPVSRYRFTLSARTQVGSGEAVTEESPAPPNEA--TPTAAPPTLPPTTVGATGAVS 944
Query: 939 PSSLKIVNPTLDSLTLEWDPPSHPNGILTEYTL--------------------------- 971
+ + T ++ T+ P P I T T+
Sbjct: 945 STDATAIAATTEATTVPIIPTVAPTTIATTTTVATTTTTTAAATTTTESPPTTTSGTKIH 1004
Query: 972 ------------------KYQPINSTHELGPLVDL---KIPANKTRWT-----------L 999
K+ I H GP D I +N T+ T L
Sbjct: 1005 ESAPDEQSIWNVTVLPNSKWANITWKHNFGPGTDFVVEYIDSNHTKKTVPVKAQAQPIQL 1064
Query: 1000 KNLNFSTRYKFYFYAQTSAGSGSQITEEAVTTVDEAMASRQVDIATQGWFIGLMCAVALL 1059
+L Y Y++ + G S + +T A + Q DIATQGWFIGLMCA+ALL
Sbjct: 1065 TDLYPGMTYTLRVYSRDNEGISSTVITFMTST---AYTNNQADIATQGWFIGLMCAIALL 1121
Query: 1060 ILILLIVCFIRRNKGGKYPVKEKEDAHADPEIQPMKEDDGTFGEYSDAEDHKPLKKGSRT 1119
+LILLIVCFI+R++GGKYPV+EK+D PE KE+DG+F +YSD ED+KPL +GS+T
Sbjct: 1122 VLILLIVCFIKRSRGGKYPVREKKDVPLGPE--DPKEEDGSF-DYSD-EDNKPL-QGSQT 1176
Query: 1120 PSDRTVKKEDSDDSLVDYGEGVNGQFNEDGSFIGQYSGKKEKEPAEGNESSEAPSPVNAM 1179
D T+K+++SDDSLVDYGEG GQFNEDGSFIGQY+ KK+KE EGNESSEA SPVNA+
Sbjct: 1177 SLDGTIKQQESDDSLVDYGEGGEGQFNEDGSFIGQYTVKKDKEETEGNESSEATSPVNAI 1236
Query: 1180 NS 1181
S
Sbjct: 1237 YS 1238
>gi|27894376 cell adhesion molecule with homology to L1CAM precursor
[Homo sapiens]
Length = 1224
Score = 875 bits (2261), Expect = 0.0
Identities = 492/1236 (39%), Positives = 688/1236 (55%), Gaps = 86/1236 (6%)
Query: 12 LSAGRVPLILFLCQMIS-ALEVPLDLVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPP 70
L G + ++FL S A+E+P + Q PTI +QS E I+CEAKG P P
Sbjct: 6 LGRGLIVYLMFLLLKFSKAIEIPSSVQQVPTIIKQSKVQVAFPFDEYFQIECEAKGNPEP 65
Query: 71 SFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNN 130
+FSWT++G F ++ P + I +EG ++G Y+C A N+ G A+S
Sbjct: 66 TFSWTKDGNPFYFTDHRII---PSNNSGTFRIPNEGHISHFQGKYRCFASNKLGIAMSEE 122
Query: 131 IVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQ 190
I P + KEK++P+ ++ G +VLPC PP GLPP I+WM+ + + Q ERV
Sbjct: 123 IEFIVPSVPKFPKEKIDPLEVEEGDPIVLPCNPPKGLPPLHIYWMNIELEHIEQDERVYM 182
Query: 191 GLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTE 250
GDLYF+NV +D+R DY C+A F +TI QK P+ + V S+ ND+ ++ ++
Sbjct: 183 SQKGDLYFANVEEKDSRNDYCCFAAFPRLRTIVQKMPMKLTVNSLKHANDSSSSTEIGSK 242
Query: 251 FYGAKSSRERPPTFLTP---EGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPK 307
A S ++R P L P G+ S+ L+G +L LEC AEGLPTP + W K G LPK
Sbjct: 243 ---ANSIKQRKPKLLLPPTESGSESSITILKGEILLLECFAEGLPTPQVDWNKIGGDLPK 299
Query: 308 NRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLS 367
R +N+ KTL+I +VS D GNY+C A N LG H V V+ P W PQ+ V S
Sbjct: 300 GRETKENYGKTLKIENVSYQDKGNYRCTASNFLGTATHDFHVIVEEPPRWTKKPQSAVYS 359
Query: 368 PGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTII-----FSNVQERSSA 422
G +G L+C A G P+P I W NG P++ P GD + F+N+Q +A
Sbjct: 360 TGSNGILLCEAEGEPQPTIKWRVNGSPVDNHP------FAGDVVFPREISFTNLQPNHTA 413
Query: 423 VYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEW 482
VYQC ASN +G +LANA ++V+ P I T Y + A L C FF SP + W
Sbjct: 414 VYQCEASNVHGTILANANIDVVDVRPLIQTKDGENYATVVGYSAFLHCEFFASPEAVVSW 473
Query: 483 FKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWI 542
K + L Y ++ENGTL+I ++ G+Y+C N +G +L+I++ T +
Sbjct: 474 QKVEEVKPLEGRRYHIYENGTLQINRTTEEDAGSYSCWVENAIGKTAVTANLDIRNATKL 533
Query: 543 VKQPEYAVVQRGSMVSFECKVKHDHTL--SLTVLWLKDNRELP----SDERFTVDKDHLV 596
P+ + + M+ C+ K D L SL + W KD D R +D +L
Sbjct: 534 RVSPKNPRIPKLHMLELHCESKCDSHLKHSLKLSWSKDGEAFEINGTEDGRIIIDGANLT 593
Query: 597 VADVSDDDSGTYTCVANTTLDSVSASAVLSVVDVPNPPFDLELTDQLDKSVQLSWTPGDD 656
+++V+ +D G Y C A+T LDS + ++V+DVP+PP +L L+++ ++SV+L+W G D
Sbjct: 594 ISNVTLEDQGIYCCSAHTALDSAADITQVTVLDVPDPPENLHLSERQNRSVRLTWEAGAD 653
Query: 657 NNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLP 716
+NS I+++I+E+E +PG W T V G +TT L L+P+V Y FRV+AVN +G+S P
Sbjct: 654 HNSNISEYIVEFEGNKEEPGRWEELTRVQGKKTTVILPLAPFVRYQFRVIAVNEVGRSQP 713
Query: 717 SEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVSWRQKDGD 776
S+ S+ + T + PD+NP + S+P ++I W+PL E NGPGL+Y+V+W+ +
Sbjct: 714 SQPSDHHETPPAAPDRNPQNIRVQASQPKEMIIKWEPLKSMEQNGPGLEYRVTWKPQGAP 773
Query: 777 DEWTSVVVANVSKYIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNV 836
EW V N + +++ + PY +KVQA+N +G P+P V +SGED P AP
Sbjct: 774 VEWEEETVTNHTLRVMT-PAVYAPYDVKVQAINQLGSGPDPQSVTLYSGEDYPDTAPVIH 832
Query: 837 RVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTH 896
V+V+NSTL +V W VP + G L+GY+I +WKT+S E IL F G +
Sbjct: 833 GVDVINSTLVKVTWSTVPKDRVHGRLKGYQINWWKTKSLLDGRTHPKEVNILRFSGQRNS 892
Query: 897 GMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEW 956
GM+P L+ FS + L V N KG GP S +F TPEGVP P+ LK++ D+ TL W
Sbjct: 893 GMVPSLDAFSEFHLTVLAYNSKGAGPESEPYIFQTPEGVPEQPTFLKVIKVDKDTATLSW 952
Query: 957 DPPSHPNGILTEYTLKYQPINSTHELGPLVDLKIPA-NKTRWTLKNLNFSTRYKFYFYAQ 1015
P NG LT Y L+YQ IN T+E+G L D+ I +K W L NLN +T+YKFY A
Sbjct: 953 GLPKKLNGNLTGYLLQYQIINDTYEIGELNDINITTPSKPSWHLSNLNATTKYKFYLRAC 1012
Query: 1016 TSAGSGSQITEEAVT-----------------------TVDEAMASRQVDIATQ------ 1046
TS G G ITEE+ T V E A V + T+
Sbjct: 1013 TSQGCGKPITEESSTLGEGSKGIGKISGVNLTQKTHPIEVFEPGAEHIVRLMTKNWGDND 1072
Query: 1047 ------------------------GWFIGLMCAVALLILILLIVCFIRRNKGGKYPVKEK 1082
GWFIGLMCA+ALL L+LL VCF++RN+GGKY VKEK
Sbjct: 1073 SIFQDVIETRGREYAGLYDDISTQGWFIGLMCAIALLTLLLLTVCFVKRNRGGKYSVKEK 1132
Query: 1083 EDAHADPEIQPMKEDDGTFGEYSDAEDHKPLKKGSRTPSDRTVKKEDSDDSLVDYGEGVN 1142
ED H DPEIQ +K D TFGEYSD+ D KPL KGS +R ++ +S DSLV+YGEG +
Sbjct: 1133 EDLHPDPEIQSVK--DETFGEYSDS-DEKPL-KGSLRSLNRDMQPTESADSLVEYGEGDH 1188
Query: 1143 GQFNEDGSFIGQYSGKKEKEPAEGNESSEAPSPVNA 1178
G F+EDGSFIG Y+G KEK E N SS A P+ A
Sbjct: 1189 GLFSEDGSFIGAYAGSKEKGSVESNGSSTATFPLRA 1224
>gi|221316760 L1 cell adhesion molecule isoform 3 precursor [Homo
sapiens]
Length = 1248
Score = 770 bits (1988), Expect = 0.0
Identities = 398/1018 (39%), Positives = 583/1018 (57%), Gaps = 30/1018 (2%)
Query: 21 LFLCQMISALEVPLDLVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTH 80
L LC +++P +L++PP IT+QSP+ ++ P ++I ++CEA GKP F WTR+G H
Sbjct: 11 LLLCSPCLLIQIPEELMEPPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWTRDGVH 70
Query: 81 FDIDKDPLVTM--KPGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRS 138
F ++ VT+ P +G+ I + A+ ++G+Y+C A N+ G A+S+ I + +
Sbjct: 71 FKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGA 130
Query: 139 PLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYF 198
P W KE ++P+ ++ G+S+VLPC PP P I+WM++ + Q ERV+ G NG+LYF
Sbjct: 131 PKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNGNLYF 190
Query: 199 SNVLPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSR 258
+NVL D DYIC+A F T+TI QK+PI ++V + + + D
Sbjct: 191 ANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMID------------------ 232
Query: 259 ERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKT 318
R P L P ++S+ L+G L LECIAEG PTP I W + G +P +R Y+N KT
Sbjct: 233 -RKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKT 291
Query: 319 LQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRA 378
LQ++ V E D G Y+C+A+N+LG+ H V V+AAPYW+ PQ+ + PGE L C+
Sbjct: 292 LQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQV 351
Query: 379 NGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLAN 438
G P+P ++W NG+P+E D +I +I SNVQ + V QC A N +G LLAN
Sbjct: 352 QGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLAN 411
Query: 439 AFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVL 498
A++ V+ P +ILT N Y + A L C FG+P+P+++W + L ++ +
Sbjct: 412 AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFP 471
Query: 499 HENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVS 558
+ NGTL I Q + TG Y C+A N +L++KD T I + P + ++GS V+
Sbjct: 472 YANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVT 531
Query: 559 FECKVKHDHTLSLTVLWLKDNR---ELPSDERFTVDKDHLVVADVSDDDSGTYTCVANTT 615
F C+ D +L ++ W D R EL +++ ++ LV+ + D G Y+CVA+T
Sbjct: 532 FTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTE 591
Query: 616 LDSVSASAVLSVVDVPNPPFDLELTD---QLDKSVQLSWTPGDDNNSPITKFIIEYEDAM 672
LD V + A L VV P P L L+D V++SW+P +D+N+PI K+ IE+ED
Sbjct: 592 LDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKE 651
Query: 673 HKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDK 732
P W+ +V G QT+ LKLSPYV+Y+FRV A+N G PS SE +T + P+K
Sbjct: 652 MAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEK 711
Query: 733 NPTAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDEWTSVVVANVSKYIV 792
NP V+G G+E N+VITWKPL + N P +QY+V WR + W +V++ +V
Sbjct: 712 NPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVSD-PFLVV 770
Query: 793 SGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDP 852
S T TFVPY IKVQA+N G PEP V +G+SGED P P + ++NS+ V W P
Sbjct: 771 SNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRP 830
Query: 853 VPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNV 912
V L ++GHL+GY + YW+ S K ++RHI K + + T +L GL P+S Y L V
Sbjct: 831 VDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEV 890
Query: 913 RVVNGKGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDPPSHPNGILTEYTLK 972
+ NG+G GPAS + F+TPEGVP P +L + + SL L W PP NG+LT Y L
Sbjct: 891 QAFNGRGSGPAS-EFTFSTPEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLS 949
Query: 973 YQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEEAVT 1030
Y P++ + +L+ P +T L +L+ RY+F A T G G I E T
Sbjct: 950 YHPLDEGGKGQLSFNLRDPELRTH-NLTDLSPHLRYRFQLQATTKEGPGEAIVREGGT 1006
Score = 238 bits (608), Expect = 2e-62
Identities = 307/1210 (25%), Positives = 482/1210 (39%), Gaps = 152/1210 (12%)
Query: 31 EVPLDLVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVT 90
E+ L P +++ K ++ E++V+ C P + N I +D VT
Sbjct: 122 EIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVT 181
Query: 91 MKPGTGTLIINIMSEGKAETY---------EGVYQCTARNERGAAVSNNIVVRPSRSPLW 141
M N+++ Y + Q + R A +N+++ R R
Sbjct: 182 MGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKA-TNSMIDRKPRLLFP 240
Query: 142 TKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNV 201
T + LQ GQ LVL C G P P I W+ S +P Q N L V
Sbjct: 241 TNSSSHLVALQ-GQPLVLECIAE-GFPTPTIKWLRPSGP-MPADRVTYQNHNKTLQLLKV 297
Query: 202 LPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERP 261
ED E Y C A N + + ++V+ A +P
Sbjct: 298 GEEDDGE-YRCLAE-NSLGSARHAYYVTVEA---------------------APYWLHKP 334
Query: 262 PTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGM----LPKNRTVYKNFEK 317
+ L G + L+C +G P P + W + +G+ L K++ Y+
Sbjct: 335 QSHLYGPGETAR----------LDCQVQGRPQPEVTW-RINGIPVEELAKDQK-YRIQRG 382
Query: 318 TLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQN--LVLSPGEDGTLI 375
L + +V +D+ QC A+N G + + V P I N + G L+
Sbjct: 383 ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQTYMAVQGSTAYLL 442
Query: 376 CRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYL 435
C+A G P P + WL + D+ T+ ++Q + Y C A+N+ +
Sbjct: 443 CKAFGAPVPSVQWLDED-GTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNV 501
Query: 436 LANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHE-- 493
A + V P +T+ + + +F S P+I W G L E
Sbjct: 502 TIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW--RGDGRDLQELG 559
Query: 494 --DIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTW----IVKQPE 547
D Y + E+G L I G Y+CVA +L + ++ L + +V
Sbjct: 560 DSDKYFI-EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDL 618
Query: 548 YAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDK----DHLVVADVSDD 603
+ + Q VS+ H+ + + +D +E+ ++ +++ K +S
Sbjct: 619 HLLTQSQVRVSWSPAEDHNAPIEKYDIEFED-KEMAPEKWYSLGKVPGNQTSTTLKLSPY 677
Query: 604 DSGTYTCVANTTLDSVSASAVLSVVDVPNP-----PFDLELTDQLDKSVQLSWTP--GDD 656
T+ A S V V P P D++ ++ ++W P D
Sbjct: 678 VHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMD 737
Query: 657 NNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLP 716
N+P ++ +++ + G W Q ++ S +V Y +V AVNS GK
Sbjct: 738 WNAPQVQYRVQWRPQGTR-GPW--QEQIVSDPFLVVSNTSTFVPYEIKVQAVNSQGKG-- 792
Query: 717 SEASEQYLTKASEPDKNPTAVEGL-GSEPDN---LVITWKPLNGFESNGPGLQYKVSWRQ 772
E +T + P A+ L G E N +++ W+P++ + G Y V++ +
Sbjct: 793 ---PEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWR 849
Query: 773 KDGDDEWTS--------VVVANVSKYIVSGTPTFVPYLIKVQALNDMGFAPE-------P 817
+ + + VV AN + I+SG + Y ++VQA N G P P
Sbjct: 850 EGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPASEFTFSTP 909
Query: 818 AVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSK 877
V GH P + + ++T + W P PL S G L GY + Y K
Sbjct: 910 EGVPGH---------PEALHLECQSNTSLLLRWQP-PL-SHNGVLTGYVLSYHPLDEGGK 958
Query: 878 R----NRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPE 933
N R E + TH L L P Y ++ +G G A E
Sbjct: 959 GQLSFNLRDPELR--------THN-LTDLSPHLRYRFQLQATTKEGPGEAI------VRE 1003
Query: 934 GVPSAPSSLKI---VNPTLDS--LTLEWDPPSHPNGILTEYTLKYQPINSTHELGPLVDL 988
G A S + ++ T + W P + + ++ + L
Sbjct: 1004 GGTMALSGISDFGNISATAGENYSVVSWVPKEGQCNF--RFHILFKALGEEKGGASLSPQ 1061
Query: 989 KIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEEAVTTVDEAMASRQVDIATQGW 1048
+ N++ +T +L T Y+ + + + + V A AT+GW
Sbjct: 1062 YVSYNQSSYTQWDLQPDTDYEIHLFKERMFRHQMAVKTNGTGRVRLPPAG----FATEGW 1117
Query: 1049 FIGLMCAVALLILILLIVCFIRRNKGGKYPVKEKEDAHADPEIQPMKEDDGTFGEYSDAE 1108
FIG + A+ LL+L+LLI+CFI+R+KGGKY VK+KED D E +PMK D TFGEYSD E
Sbjct: 1118 FIGFVSAIILLLLVLLILCFIKRSKGGKYSVKDKEDTQVDSEARPMK--DETFGEYSDNE 1175
Query: 1109 DHKPLKKGSRTPS-DRTVKKEDSDDSLVDYGEGVNGQFNEDGSFIGQYSGKKEKEPAEGN 1167
+ GS PS + +K SDDSL DYG V+ QFNEDGSFIGQYSGKKEKE A GN
Sbjct: 1176 EK---AFGSSQPSLNGDIKPLGSDDSLADYGGSVDVQFNEDGSFIGQYSGKKEKEAAGGN 1232
Query: 1168 ESSEAPSPVN 1177
+SS A SP+N
Sbjct: 1233 DSSGATSPIN 1242
>gi|13435353 L1 cell adhesion molecule isoform 2 precursor [Homo
sapiens]
Length = 1253
Score = 763 bits (1969), Expect = 0.0
Identities = 397/1023 (38%), Positives = 583/1023 (56%), Gaps = 35/1023 (3%)
Query: 21 LFLCQMISALEVPLD-----LVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWT 75
L LC +++P + +++PP IT+QSP+ ++ P ++I ++CEA GKP F WT
Sbjct: 11 LLLCSPCLLIQIPEEYEGHHVMEPPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWT 70
Query: 76 RNGTHFDIDKDPLVTM--KPGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVV 133
R+G HF ++ VT+ P +G+ I + A+ ++G+Y+C A N+ G A+S+ I +
Sbjct: 71 RDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRL 130
Query: 134 RPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLN 193
+P W KE ++P+ ++ G+S+VLPC PP P I+WM++ + Q ERV+ G N
Sbjct: 131 MAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQN 190
Query: 194 GDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYG 253
G+LYF+NVL D DYIC+A F T+TI QK+PI ++V + + + D
Sbjct: 191 GNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMID------------- 237
Query: 254 AKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYK 313
R P L P ++S+ L+G L LECIAEG PTP I W + G +P +R Y+
Sbjct: 238 ------RKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ 291
Query: 314 NFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGT 373
N KTLQ++ V E D G Y+C+A+N+LG+ H V V+AAPYW+ PQ+ + PGE
Sbjct: 292 NHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETAR 351
Query: 374 LICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYG 433
L C+ G P+P ++W NG+P+E D +I +I SNVQ + V QC A N +G
Sbjct: 352 LDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHG 411
Query: 434 YLLANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHE 493
LLANA++ V+ P +ILT N Y + A L C FG+P+P+++W + L +
Sbjct: 412 LLLANAYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQD 471
Query: 494 DIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQR 553
+ + + NGTL I Q + TG Y C+A N +L++KD T I + P + ++
Sbjct: 472 ERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKK 531
Query: 554 GSMVSFECKVKHDHTLSLTVLWLKDNR---ELPSDERFTVDKDHLVVADVSDDDSGTYTC 610
GS V+F C+ D +L ++ W D R EL +++ ++ LV+ + D G Y+C
Sbjct: 532 GSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSC 591
Query: 611 VANTTLDSVSASAVLSVVDVPNPPFDLELTD---QLDKSVQLSWTPGDDNNSPITKFIIE 667
VA+T LD V + A L VV P P L L+D V++SW+P +D+N+PI K+ IE
Sbjct: 592 VASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIE 651
Query: 668 YEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKA 727
+ED P W+ +V G QT+ LKLSPYV+Y+FRV A+N G PS SE +T
Sbjct: 652 FEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPE 711
Query: 728 SEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDEWTSVVVANV 787
+ P+KNP V+G G+E N+VITWKPL + N P +QY+V WR + W +V++
Sbjct: 712 AAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVSD- 770
Query: 788 SKYIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAE 847
+VS T TFVPY IKVQA+N G PEP V +G+SGED P P + ++NS+
Sbjct: 771 PFLVVSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVL 830
Query: 848 VHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSH 907
V W PV L ++GHL+GY + YW+ S K ++RHI K + + T +L GL P+S
Sbjct: 831 VKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSS 890
Query: 908 YTLNVRVVNGKGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDPPSHPNGILT 967
Y L V+ NG+G GPAS + F+TPEGVP P +L + + SL L W PP NG+LT
Sbjct: 891 YHLEVQAFNGRGSGPAS-EFTFSTPEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLT 949
Query: 968 EYTLKYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEE 1027
Y L Y P++ + +L+ P +T L +L+ RY+F A T G G I E
Sbjct: 950 GYVLSYHPLDEGGKGQLSFNLRDPELRTH-NLTDLSPHLRYRFQLQATTKEGPGEAIVRE 1008
Query: 1028 AVT 1030
T
Sbjct: 1009 GGT 1011
Score = 238 bits (608), Expect = 2e-62
Identities = 307/1210 (25%), Positives = 482/1210 (39%), Gaps = 152/1210 (12%)
Query: 31 EVPLDLVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVT 90
E+ L P +++ K ++ E++V+ C P + N I +D VT
Sbjct: 127 EIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVT 186
Query: 91 MKPGTGTLIINIMSEGKAETY---------EGVYQCTARNERGAAVSNNIVVRPSRSPLW 141
M N+++ Y + Q + R A +N+++ R R
Sbjct: 187 MGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKA-TNSMIDRKPRLLFP 245
Query: 142 TKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNV 201
T + LQ GQ LVL C G P P I W+ S +P Q N L V
Sbjct: 246 TNSSSHLVALQ-GQPLVLECIAE-GFPTPTIKWLRPSGP-MPADRVTYQNHNKTLQLLKV 302
Query: 202 LPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERP 261
ED E Y C A N + + ++V+ A +P
Sbjct: 303 GEEDDGE-YRCLAE-NSLGSARHAYYVTVEA---------------------APYWLHKP 339
Query: 262 PTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGM----LPKNRTVYKNFEK 317
+ L G + L+C +G P P + W + +G+ L K++ Y+
Sbjct: 340 QSHLYGPGETAR----------LDCQVQGRPQPEVTW-RINGIPVEELAKDQK-YRIQRG 387
Query: 318 TLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQN--LVLSPGEDGTLI 375
L + +V +D+ QC A+N G + + V P I N + G L+
Sbjct: 388 ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQTYMAVQGSTAYLL 447
Query: 376 CRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYL 435
C+A G P P + WL + D+ T+ ++Q + Y C A+N+ +
Sbjct: 448 CKAFGAPVPSVQWLDED-GTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNV 506
Query: 436 LANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHE-- 493
A + V P +T+ + + +F S P+I W G L E
Sbjct: 507 TIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW--RGDGRDLQELG 564
Query: 494 --DIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTW----IVKQPE 547
D Y + E+G L I G Y+CVA +L + ++ L + +V
Sbjct: 565 DSDKYFI-EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDL 623
Query: 548 YAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDK----DHLVVADVSDD 603
+ + Q VS+ H+ + + +D +E+ ++ +++ K +S
Sbjct: 624 HLLTQSQVRVSWSPAEDHNAPIEKYDIEFED-KEMAPEKWYSLGKVPGNQTSTTLKLSPY 682
Query: 604 DSGTYTCVANTTLDSVSASAVLSVVDVPNP-----PFDLELTDQLDKSVQLSWTP--GDD 656
T+ A S V V P P D++ ++ ++W P D
Sbjct: 683 VHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMD 742
Query: 657 NNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLP 716
N+P ++ +++ + G W Q ++ S +V Y +V AVNS GK
Sbjct: 743 WNAPQVQYRVQWRPQGTR-GPW--QEQIVSDPFLVVSNTSTFVPYEIKVQAVNSQGKG-- 797
Query: 717 SEASEQYLTKASEPDKNPTAVEGL-GSEPDN---LVITWKPLNGFESNGPGLQYKVSWRQ 772
E +T + P A+ L G E N +++ W+P++ + G Y V++ +
Sbjct: 798 ---PEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWR 854
Query: 773 KDGDDEWTS--------VVVANVSKYIVSGTPTFVPYLIKVQALNDMGFAPE-------P 817
+ + + VV AN + I+SG + Y ++VQA N G P P
Sbjct: 855 EGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPASEFTFSTP 914
Query: 818 AVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSK 877
V GH P + + ++T + W P PL S G L GY + Y K
Sbjct: 915 EGVPGH---------PEALHLECQSNTSLLLRWQP-PL-SHNGVLTGYVLSYHPLDEGGK 963
Query: 878 R----NRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPE 933
N R E + TH L L P Y ++ +G G A E
Sbjct: 964 GQLSFNLRDPELR--------THN-LTDLSPHLRYRFQLQATTKEGPGEAI------VRE 1008
Query: 934 GVPSAPSSLKI---VNPTLDS--LTLEWDPPSHPNGILTEYTLKYQPINSTHELGPLVDL 988
G A S + ++ T + W P + + ++ + L
Sbjct: 1009 GGTMALSGISDFGNISATAGENYSVVSWVPKEGQCNF--RFHILFKALGEEKGGASLSPQ 1066
Query: 989 KIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEEAVTTVDEAMASRQVDIATQGW 1048
+ N++ +T +L T Y+ + + + + V A AT+GW
Sbjct: 1067 YVSYNQSSYTQWDLQPDTDYEIHLFKERMFRHQMAVKTNGTGRVRLPPAG----FATEGW 1122
Query: 1049 FIGLMCAVALLILILLIVCFIRRNKGGKYPVKEKEDAHADPEIQPMKEDDGTFGEYSDAE 1108
FIG + A+ LL+L+LLI+CFI+R+KGGKY VK+KED D E +PMK D TFGEYSD E
Sbjct: 1123 FIGFVSAIILLLLVLLILCFIKRSKGGKYSVKDKEDTQVDSEARPMK--DETFGEYSDNE 1180
Query: 1109 DHKPLKKGSRTPS-DRTVKKEDSDDSLVDYGEGVNGQFNEDGSFIGQYSGKKEKEPAEGN 1167
+ GS PS + +K SDDSL DYG V+ QFNEDGSFIGQYSGKKEKE A GN
Sbjct: 1181 EK---AFGSSQPSLNGDIKPLGSDDSLADYGGSVDVQFNEDGSFIGQYSGKKEKEAAGGN 1237
Query: 1168 ESSEAPSPVN 1177
+SS A SP+N
Sbjct: 1238 DSSGATSPIN 1247
>gi|4557707 L1 cell adhesion molecule isoform 1 precursor [Homo
sapiens]
Length = 1257
Score = 763 bits (1969), Expect = 0.0
Identities = 397/1023 (38%), Positives = 583/1023 (56%), Gaps = 35/1023 (3%)
Query: 21 LFLCQMISALEVPLD-----LVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWT 75
L LC +++P + +++PP IT+QSP+ ++ P ++I ++CEA GKP F WT
Sbjct: 11 LLLCSPCLLIQIPEEYEGHHVMEPPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWT 70
Query: 76 RNGTHFDIDKDPLVTM--KPGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVV 133
R+G HF ++ VT+ P +G+ I + A+ ++G+Y+C A N+ G A+S+ I +
Sbjct: 71 RDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRL 130
Query: 134 RPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLN 193
+P W KE ++P+ ++ G+S+VLPC PP P I+WM++ + Q ERV+ G N
Sbjct: 131 MAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQN 190
Query: 194 GDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYG 253
G+LYF+NVL D DYIC+A F T+TI QK+PI ++V + + + D
Sbjct: 191 GNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMID------------- 237
Query: 254 AKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYK 313
R P L P ++S+ L+G L LECIAEG PTP I W + G +P +R Y+
Sbjct: 238 ------RKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ 291
Query: 314 NFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGT 373
N KTLQ++ V E D G Y+C+A+N+LG+ H V V+AAPYW+ PQ+ + PGE
Sbjct: 292 NHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETAR 351
Query: 374 LICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYG 433
L C+ G P+P ++W NG+P+E D +I +I SNVQ + V QC A N +G
Sbjct: 352 LDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHG 411
Query: 434 YLLANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHE 493
LLANA++ V+ P +ILT N Y + A L C FG+P+P+++W + L +
Sbjct: 412 LLLANAYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQD 471
Query: 494 DIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQR 553
+ + + NGTL I Q + TG Y C+A N +L++KD T I + P + ++
Sbjct: 472 ERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKK 531
Query: 554 GSMVSFECKVKHDHTLSLTVLWLKDNR---ELPSDERFTVDKDHLVVADVSDDDSGTYTC 610
GS V+F C+ D +L ++ W D R EL +++ ++ LV+ + D G Y+C
Sbjct: 532 GSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSC 591
Query: 611 VANTTLDSVSASAVLSVVDVPNPPFDLELTD---QLDKSVQLSWTPGDDNNSPITKFIIE 667
VA+T LD V + A L VV P P L L+D V++SW+P +D+N+PI K+ IE
Sbjct: 592 VASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIE 651
Query: 668 YEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKA 727
+ED P W+ +V G QT+ LKLSPYV+Y+FRV A+N G PS SE +T
Sbjct: 652 FEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPE 711
Query: 728 SEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDEWTSVVVANV 787
+ P+KNP V+G G+E N+VITWKPL + N P +QY+V WR + W +V++
Sbjct: 712 AAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVSD- 770
Query: 788 SKYIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAE 847
+VS T TFVPY IKVQA+N G PEP V +G+SGED P P + ++NS+
Sbjct: 771 PFLVVSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVL 830
Query: 848 VHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSH 907
V W PV L ++GHL+GY + YW+ S K ++RHI K + + T +L GL P+S
Sbjct: 831 VKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSS 890
Query: 908 YTLNVRVVNGKGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDPPSHPNGILT 967
Y L V+ NG+G GPAS + F+TPEGVP P +L + + SL L W PP NG+LT
Sbjct: 891 YHLEVQAFNGRGSGPAS-EFTFSTPEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLT 949
Query: 968 EYTLKYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEE 1027
Y L Y P++ + +L+ P +T L +L+ RY+F A T G G I E
Sbjct: 950 GYVLSYHPLDEGGKGQLSFNLRDPELRTH-NLTDLSPHLRYRFQLQATTKEGPGEAIVRE 1008
Query: 1028 AVT 1030
T
Sbjct: 1009 GGT 1011
Score = 237 bits (604), Expect = 6e-62
Identities = 306/1211 (25%), Positives = 482/1211 (39%), Gaps = 150/1211 (12%)
Query: 31 EVPLDLVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVT 90
E+ L P +++ K ++ E++V+ C P + N I +D VT
Sbjct: 127 EIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVT 186
Query: 91 MKPGTGTLIINIMSEGKAETY---------EGVYQCTARNERGAAVSNNIVVRPSRSPLW 141
M N+++ Y + Q + R A +N+++ R R
Sbjct: 187 MGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKA-TNSMIDRKPRLLFP 245
Query: 142 TKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNV 201
T + LQ GQ LVL C G P P I W+ S +P Q N L V
Sbjct: 246 TNSSSHLVALQ-GQPLVLECIAE-GFPTPTIKWLRPSGP-MPADRVTYQNHNKTLQLLKV 302
Query: 202 LPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERP 261
ED E Y C A N + + ++V+ A +P
Sbjct: 303 GEEDDGE-YRCLAE-NSLGSARHAYYVTVEA---------------------APYWLHKP 339
Query: 262 PTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGM----LPKNRTVYKNFEK 317
+ L G + L+C +G P P + W + +G+ L K++ Y+
Sbjct: 340 QSHLYGPGETAR----------LDCQVQGRPQPEVTW-RINGIPVEELAKDQK-YRIQRG 387
Query: 318 TLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQN--LVLSPGEDGTLI 375
L + +V +D+ QC A+N G + + V P I N + G L+
Sbjct: 388 ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQTYMAVQGSTAYLL 447
Query: 376 CRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYL 435
C+A G P P + WL + D+ T+ ++Q + Y C A+N+ +
Sbjct: 448 CKAFGAPVPSVQWLDED-GTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNV 506
Query: 436 LANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHE-- 493
A + V P +T+ + + +F S P+I W G L E
Sbjct: 507 TIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW--RGDGRDLQELG 564
Query: 494 --DIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTW----IVKQPE 547
D Y + E+G L I G Y+CVA +L + ++ L + +V
Sbjct: 565 DSDKYFI-EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDL 623
Query: 548 YAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDK----DHLVVADVSDD 603
+ + Q VS+ H+ + + +D +E+ ++ +++ K +S
Sbjct: 624 HLLTQSQVRVSWSPAEDHNAPIEKYDIEFED-KEMAPEKWYSLGKVPGNQTSTTLKLSPY 682
Query: 604 DSGTYTCVANTTLDSVSASAVLSVVDVPNP-----PFDLELTDQLDKSVQLSWTP--GDD 656
T+ A S V V P P D++ ++ ++W P D
Sbjct: 683 VHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMD 742
Query: 657 NNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLP 716
N+P ++ +++ + G W Q ++ S +V Y +V AVNS GK
Sbjct: 743 WNAPQVQYRVQWRPQGTR-GPW--QEQIVSDPFLVVSNTSTFVPYEIKVQAVNSQGKG-- 797
Query: 717 SEASEQYLTKASEPDKNPTAVEGL-GSEPDN---LVITWKPLNGFESNGPGLQYKVSWRQ 772
E +T + P A+ L G E N +++ W+P++ + G Y V++ +
Sbjct: 798 ---PEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWR 854
Query: 773 KDGDDEWTS--------VVVANVSKYIVSGTPTFVPYLIKVQALNDMGFAPE-------P 817
+ + + VV AN + I+SG + Y ++VQA N G P P
Sbjct: 855 EGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPASEFTFSTP 914
Query: 818 AVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSK 877
V GH P + + ++T + W P PL S G L GY + Y K
Sbjct: 915 EGVPGH---------PEALHLECQSNTSLLLRWQP-PL-SHNGVLTGYVLSYHPLDEGGK 963
Query: 878 R----NRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPE 933
N R E + TH L L P Y ++ +G G A E
Sbjct: 964 GQLSFNLRDPELR--------THN-LTDLSPHLRYRFQLQATTKEGPGEAI------VRE 1008
Query: 934 GVPSAPSSLKI---VNPTLDS--LTLEWDPPSHPNGILTEYTLKYQPINSTHELGPLVDL 988
G A S + ++ T + W P + + ++ + L
Sbjct: 1009 GGTMALSGISDFGNISATAGENYSVVSWVPKEGQCNF--RFHILFKALGEEKGGASLSPQ 1066
Query: 989 KIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEEAVTTVDEAMASRQVDIATQGW 1048
+ N++ +T +L T Y+ + + + + V A AT+GW
Sbjct: 1067 YVSYNQSSYTQWDLQPDTDYEIHLFKERMFRHQMAVKTNGTGRVRLPPAG----FATEGW 1122
Query: 1049 FIGLMCAVALLILILLIVCFIRRNKGGKYPVKEKEDAHADPEIQPMKEDDGTFGEYSDAE 1108
FIG + A+ LL+L+LLI+CFI+R+KGGKY VK+KED D E +PMK D TFGEY E
Sbjct: 1123 FIGFVSAIILLLLVLLILCFIKRSKGGKYSVKDKEDTQVDSEARPMK--DETFGEYRSLE 1180
Query: 1109 -DHKPLKKGSRTPS-DRTVKKEDSDDSLVDYGEGVNGQFNEDGSFIGQYSGKKEKEPAEG 1166
D++ GS PS + +K SDDSL DYG V+ QFNEDGSFIGQYSGKKEKE A G
Sbjct: 1181 SDNEEKAFGSSQPSLNGDIKPLGSDDSLADYGGSVDVQFNEDGSFIGQYSGKKEKEAAGG 1240
Query: 1167 NESSEAPSPVN 1177
N+SS A SP+N
Sbjct: 1241 NDSSGATSPIN 1251
>gi|237858682 neurofascin isoform 6 precursor [Homo sapiens]
Length = 613
Score = 667 bits (1721), Expect = 0.0
Identities = 324/609 (53%), Positives = 425/609 (69%), Gaps = 19/609 (3%)
Query: 20 ILFLCQMISALEVPLDLVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGT 79
+L L + A+E+P+DL QPPTIT+QS KD+I+DPR+NI+I+CEAKG P PSF WTRN
Sbjct: 15 LLCLLSLGGAIEIPMDLTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSR 74
Query: 80 HFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSP 139
F+I KDP V+M+ +GTL+I+ S G+ E YEG YQC ARN+ G A+SN I ++ S+SP
Sbjct: 75 FFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSP 134
Query: 140 LWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFS 199
LW KE L+P+ +Q G L L C PP GLP P+IFWM +S + + Q +RVSQG NGDLYFS
Sbjct: 135 LWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFS 194
Query: 200 NVLPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRE 259
NV+ +D + DY C ARF+ T TIQQK P ++KV++ + E
Sbjct: 195 NVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTT-------------------RGVAE 235
Query: 260 RPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTL 319
R P+F+ P+G AS++ LRG L LECIA G+PTP I W K+ G LP ++ ++NF K L
Sbjct: 236 RTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKAL 295
Query: 320 QIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRAN 379
+I +VSE DSG Y C+A N +G+I HTISVRVKAAPYW+ P+NL+L+PGEDG L+CRAN
Sbjct: 296 RITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRAN 355
Query: 380 GNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANA 439
GNPKP + W+ NG P++ AP +P+R++ GDTIIF + Q S AVYQCN SNE+GYLLANA
Sbjct: 356 GNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANA 415
Query: 440 FVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLH 499
FV+VL PPR+L+P N L +VI LDC FFGSP+PT+ WFK +GS L Y ++
Sbjct: 416 FVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVY 475
Query: 500 ENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSF 559
ENG+LEI + +K+ G YTCVA N LG A+N+V LE+KDPT I + PE V +RG+ V
Sbjct: 476 ENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQL 535
Query: 560 ECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVADVSDDDSGTYTCVANTTLDSV 619
EC+VKHD +L LTV WLKD+ L R + D L + V++ D G+YTCVA+T LD
Sbjct: 536 ECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVAERDQGSYTCVASTELDQD 595
Query: 620 SASAVLSVV 628
A A L+V+
Sbjct: 596 LAKAYLTVL 604
Score = 109 bits (272), Expect = 2e-23
Identities = 106/400 (26%), Positives = 169/400 (42%), Gaps = 37/400 (9%)
Query: 260 RPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKED---GMLPKNRTVYKNFE 316
+PPT +T + + + R N+L +EC A+G P P +W + + R +
Sbjct: 33 QPPT-ITKQSAKDHIVDPRDNIL-IECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRS 90
Query: 317 KTLQIIHVS----EADSGNYQCIAKNALG-AIHHTISVRVKAAPYWITAPQNL---VLSP 368
TL I S E G YQC A+N G A+ + I ++V +P W +NL V+
Sbjct: 91 GTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLW--PKENLDPVVVQE 148
Query: 369 GEDGTLICRAN-GNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAV-YQC 426
G TL C G P P I W+++ + S+ +GD + FSNV + Y C
Sbjct: 149 GAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGD-LYFSNVMLQDMQTDYSC 207
Query: 427 NASNEYGYLLA--NAFV-------NVLAEPPRILTPANTL--YQVIANRPALLDCAFFGS 475
NA + + + N F V P + P T V+ LL+C G
Sbjct: 208 NARFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGV 267
Query: 476 PLPTIEWFKGAKGSALHEDIYVLHE-NGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHL 534
P P I W+K KG L D N L I ++ +G Y C+A NK+G ++ + +
Sbjct: 268 PTPDIAWYK--KGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISV 325
Query: 535 EIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNREL---PSDERFTVD 591
+K + + +P+ ++ G C+ + TV W+ + L P + V
Sbjct: 326 RVKAAPYWLDEPKNLILAPGEDGRLVCRANGNP--KPTVQWMVNGEPLQSAPPNPNREVA 383
Query: 592 KDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVDVP 631
D ++ D Y C + + A+A +SV+DVP
Sbjct: 384 GDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVP 423
Score = 76.3 bits (186), Expect = 2e-13
Identities = 119/525 (22%), Positives = 193/525 (36%), Gaps = 73/525 (13%)
Query: 136 SRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNS-FQRLPQSERVS-QGLN 193
++ P TK+ + + ++++ C G P P W NS F + + RVS + +
Sbjct: 32 TQPPTITKQSAKDHIVDPRDNILIECEAK-GNPAPSFHWTRNSRFFNIAKDPRVSMRRRS 90
Query: 194 GDL---YFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTE 250
G L + S PE+ +Y C+AR + + + V
Sbjct: 91 GTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQV-------------------- 130
Query: 251 FYGAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAE-GLPTPIIYWAKED-GMLPKN 308
+KS L P+ N G L+L+C GLP+P+I+W + ++
Sbjct: 131 ---SKSP-------LWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQD 180
Query: 309 RTVYKNFEKTLQIIHVSEAD-SGNYQCIAKNALGAIHHTISVR-------------VKAA 354
+ V + L +V D +Y C NA HTI + +
Sbjct: 181 KRVSQGHNGDLYFSNVMLQDMQTDYSC---NARFHFTHTIQQKNPFTLKVLTTRGVAERT 237
Query: 355 PYWI----TAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDT 410
P ++ TA +VL G D L C A+G P P I+W G + P D ++ + +
Sbjct: 238 PSFMYPQGTASSQMVLR-GMDLLLECIASGVPTPDIAWYKKGGDL---PSDKAKFENFNK 293
Query: 411 II-FSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIANRPALLD 469
+ +NV E S Y C ASN+ G + V V A P + P N + + L
Sbjct: 294 ALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLI--LAPGEDGRLV 351
Query: 470 CAFFGSPLPTIEWF-KGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMA 528
C G+P PT++W G + + T+ Q S Y C N+ G
Sbjct: 352 CRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYL 411
Query: 529 KNEVHLEIKD--PTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNR--ELPS 584
+ + D P + + + V + +C +L W K+ + L
Sbjct: 412 LANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLR--WFKNGQGSNLDG 469
Query: 585 DERFTVDKDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVD 629
+ L + + +D G YTCVA L L V D
Sbjct: 470 GNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKD 514
Score = 73.6 bits (179), Expect = 1e-12
Identities = 86/343 (25%), Positives = 133/343 (38%), Gaps = 45/343 (13%)
Query: 365 VLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDD--PSRKIDGDTII---FSNVQER 419
++ P ++ + C A GNP P W N IA D R+ G +I E
Sbjct: 46 IVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEE 105
Query: 420 SSAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIANR--PALLDC-AFFGSP 476
YQC A N++G L+N +++ P L P L V+ P L C G P
Sbjct: 106 YEGEYQCFARNKFGTALSNRIRLQVSKSP--LWPKENLDPVVVQEGAPLTLQCNPPPGLP 163
Query: 477 LPTIEWFKGAKGSALHEDIYVLHENGTLEIP-VAQKDSTGTYTCVARNKLG---MAKNEV 532
P I W + + NG L V +D Y+C AR KN
Sbjct: 164 SPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPF 223
Query: 533 HLEI--------KDPTWIVKQPEYA--VVQRGSMVSFECKVKHDHTLSLTVLWLKDNREL 582
L++ + P+++ Q + +V RG + EC T + W K +L
Sbjct: 224 TLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIA--WYKKGGDL 281
Query: 583 PSDE-RFTVDKDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVDVPNPPFDLELTD 641
PSD+ +F L + +VS++DSG Y C+A+ + S+ + + V P
Sbjct: 282 PSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPY--------- 332
Query: 642 QLDKSVQLSWTPGDD---------NNSPITKFIIEYEDAMHKP 675
LD+ L PG+D N P ++++ E P
Sbjct: 333 WLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAP 375
>gi|237858680 neurofascin isoform 5 precursor [Homo sapiens]
Length = 619
Score = 660 bits (1704), Expect = 0.0
Identities = 324/615 (52%), Positives = 425/615 (69%), Gaps = 25/615 (4%)
Query: 20 ILFLCQMISALEVPLD------LVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFS 73
+L L + A+E+P+D L QPPTIT+QS KD+I+DPR+NI+I+CEAKG P PSF
Sbjct: 15 LLCLLSLGGAIEIPMDPSIQNELTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFH 74
Query: 74 WTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVV 133
WTRN F+I KDP V+M+ +GTL+I+ S G+ E YEG YQC ARN+ G A+SN I +
Sbjct: 75 WTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRL 134
Query: 134 RPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLN 193
+ S+SPLW KE L+P+ +Q G L L C PP GLP P+IFWM +S + + Q +RVSQG N
Sbjct: 135 QVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHN 194
Query: 194 GDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYG 253
GDLYFSNV+ +D + DY C ARF+ T TIQQK P ++KV++
Sbjct: 195 GDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTT------------------ 236
Query: 254 AKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYK 313
+ ER P+F+ P+G AS++ LRG L LECIA G+PTP I W K+ G LP ++ ++
Sbjct: 237 -RGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFE 295
Query: 314 NFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGT 373
NF K L+I +VSE DSG Y C+A N +G+I HTISVRVKAAPYW+ P+NL+L+PGEDG
Sbjct: 296 NFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGR 355
Query: 374 LICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYG 433
L+CRANGNPKP + W+ NG P++ AP +P+R++ GDTIIF + Q S AVYQCN SNE+G
Sbjct: 356 LVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHG 415
Query: 434 YLLANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHE 493
YLLANAFV+VL PPR+L+P N L +VI LDC FFGSP+PT+ WFK +GS L
Sbjct: 416 YLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDG 475
Query: 494 DIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQR 553
Y ++ENG+LEI + +K+ G YTCVA N LG A+N+V LE+KDPT I + PE V +R
Sbjct: 476 GNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARR 535
Query: 554 GSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVADVSDDDSGTYTCVAN 613
G+ V EC+VKHD +L LTV WLKD+ L R + D L + V++ D G+YTCVA+
Sbjct: 536 GTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVAERDQGSYTCVAS 595
Query: 614 TTLDSVSASAVLSVV 628
T LD A A L+V+
Sbjct: 596 TELDQDLAKAYLTVL 610
Score = 109 bits (272), Expect = 2e-23
Identities = 106/400 (26%), Positives = 169/400 (42%), Gaps = 37/400 (9%)
Query: 260 RPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKED---GMLPKNRTVYKNFE 316
+PPT +T + + + R N+L +EC A+G P P +W + + R +
Sbjct: 39 QPPT-ITKQSAKDHIVDPRDNIL-IECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRS 96
Query: 317 KTLQIIHVS----EADSGNYQCIAKNALG-AIHHTISVRVKAAPYWITAPQNL---VLSP 368
TL I S E G YQC A+N G A+ + I ++V +P W +NL V+
Sbjct: 97 GTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLW--PKENLDPVVVQE 154
Query: 369 GEDGTLICRAN-GNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAV-YQC 426
G TL C G P P I W+++ + S+ +GD + FSNV + Y C
Sbjct: 155 GAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGD-LYFSNVMLQDMQTDYSC 213
Query: 427 NASNEYGYLLA--NAFV-------NVLAEPPRILTPANTL--YQVIANRPALLDCAFFGS 475
NA + + + N F V P + P T V+ LL+C G
Sbjct: 214 NARFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGV 273
Query: 476 PLPTIEWFKGAKGSALHEDIYVLHE-NGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHL 534
P P I W+K KG L D N L I ++ +G Y C+A NK+G ++ + +
Sbjct: 274 PTPDIAWYK--KGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISV 331
Query: 535 EIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNREL---PSDERFTVD 591
+K + + +P+ ++ G C+ + TV W+ + L P + V
Sbjct: 332 RVKAAPYWLDEPKNLILAPGEDGRLVCRANGNP--KPTVQWMVNGEPLQSAPPNPNREVA 389
Query: 592 KDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVDVP 631
D ++ D Y C + + A+A +SV+DVP
Sbjct: 390 GDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVP 429
Score = 76.3 bits (186), Expect = 2e-13
Identities = 119/525 (22%), Positives = 193/525 (36%), Gaps = 73/525 (13%)
Query: 136 SRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNS-FQRLPQSERVS-QGLN 193
++ P TK+ + + ++++ C G P P W NS F + + RVS + +
Sbjct: 38 TQPPTITKQSAKDHIVDPRDNILIECEAK-GNPAPSFHWTRNSRFFNIAKDPRVSMRRRS 96
Query: 194 GDL---YFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTE 250
G L + S PE+ +Y C+AR + + + V
Sbjct: 97 GTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQV-------------------- 136
Query: 251 FYGAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAE-GLPTPIIYWAKED-GMLPKN 308
+KS L P+ N G L+L+C GLP+P+I+W + ++
Sbjct: 137 ---SKSP-------LWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQD 186
Query: 309 RTVYKNFEKTLQIIHVSEAD-SGNYQCIAKNALGAIHHTISVR-------------VKAA 354
+ V + L +V D +Y C NA HTI + +
Sbjct: 187 KRVSQGHNGDLYFSNVMLQDMQTDYSC---NARFHFTHTIQQKNPFTLKVLTTRGVAERT 243
Query: 355 PYWI----TAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDT 410
P ++ TA +VL G D L C A+G P P I+W G + P D ++ + +
Sbjct: 244 PSFMYPQGTASSQMVLR-GMDLLLECIASGVPTPDIAWYKKGGDL---PSDKAKFENFNK 299
Query: 411 II-FSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIANRPALLD 469
+ +NV E S Y C ASN+ G + V V A P + P N + + L
Sbjct: 300 ALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLI--LAPGEDGRLV 357
Query: 470 CAFFGSPLPTIEWF-KGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMA 528
C G+P PT++W G + + T+ Q S Y C N+ G
Sbjct: 358 CRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYL 417
Query: 529 KNEVHLEIKD--PTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNR--ELPS 584
+ + D P + + + V + +C +L W K+ + L
Sbjct: 418 LANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLR--WFKNGQGSNLDG 475
Query: 585 DERFTVDKDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVD 629
+ L + + +D G YTCVA L L V D
Sbjct: 476 GNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKD 520
Score = 73.6 bits (179), Expect = 1e-12
Identities = 86/343 (25%), Positives = 133/343 (38%), Gaps = 45/343 (13%)
Query: 365 VLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDD--PSRKIDGDTII---FSNVQER 419
++ P ++ + C A GNP P W N IA D R+ G +I E
Sbjct: 52 IVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEE 111
Query: 420 SSAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIANR--PALLDC-AFFGSP 476
YQC A N++G L+N +++ P L P L V+ P L C G P
Sbjct: 112 YEGEYQCFARNKFGTALSNRIRLQVSKSP--LWPKENLDPVVVQEGAPLTLQCNPPPGLP 169
Query: 477 LPTIEWFKGAKGSALHEDIYVLHENGTLEIP-VAQKDSTGTYTCVARNKLG---MAKNEV 532
P I W + + NG L V +D Y+C AR KN
Sbjct: 170 SPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPF 229
Query: 533 HLEI--------KDPTWIVKQPEYA--VVQRGSMVSFECKVKHDHTLSLTVLWLKDNREL 582
L++ + P+++ Q + +V RG + EC T + W K +L
Sbjct: 230 TLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIA--WYKKGGDL 287
Query: 583 PSDE-RFTVDKDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVDVPNPPFDLELTD 641
PSD+ +F L + +VS++DSG Y C+A+ + S+ + + V P
Sbjct: 288 PSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPY--------- 338
Query: 642 QLDKSVQLSWTPGDD---------NNSPITKFIIEYEDAMHKP 675
LD+ L PG+D N P ++++ E P
Sbjct: 339 WLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAP 381
>gi|4827022 contactin 2 precursor [Homo sapiens]
Length = 1040
Score = 376 bits (965), Expect = e-104
Identities = 284/941 (30%), Positives = 425/941 (45%), Gaps = 65/941 (6%)
Query: 56 ENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVY 115
E +++ C A+ PP ++ W NGT ++ + G + IM+ KA+ GVY
Sbjct: 55 EQVLLACRARASPPATYRWKMNGTEMKLEPGSRHQLVGGN----LVIMNPTKAQD-AGVY 109
Query: 116 QCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWM 175
QC A N G VS ++R ++KE+ +P+ G ++LPC PP P W+
Sbjct: 110 QCLASNPVGTVVSREAILRFGFLQEFSKEERDPVKAHEGWGVMLPCNPPAHYPGLSYRWL 169
Query: 176 DNSFQR-LPQSER--VSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKV 232
N F +P R VSQ G+LY + D +Y C A + S K
Sbjct: 170 LNEFPNFIPTDGRHFVSQ-TTGNLYIARTNASDLG-NYSCLATSH--------MDFSTKS 219
Query: 233 ISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLP 292
+ +AA DT + A S + R P + L G ++LEC A G P
Sbjct: 220 VFSKFAQLNLAAE--DTRLF-APSIKARFP---------AETYALVGQQVTLECFAFGNP 267
Query: 293 TPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVK 352
P I W K DG L T E TLQI VS D G Y+C A+N+ G + V+
Sbjct: 268 VPRIKWRKVDGSLSPQWTTA---EPTLQIPSVSFEDEGTYECEAENSKGRDTVQGRIIVQ 324
Query: 353 AAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTII 412
A P W+ + G + C A G P+P + WL NG P+ A + + GD +
Sbjct: 325 AQPEWLKVISDTEADIGSNLRWGCAAAGKPRPTVRWLRNGEPL--ASQNRVEVLAGD-LR 381
Query: 413 FSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRI-LTPANTLYQVIANRPALLDCA 471
FS + S +YQC A N++G + A+A + V A P L P L L+ C
Sbjct: 382 FSKLSLEDSGMYQCVAENKHGTIYASAELAVQALAPDFRLNPVRRLIPAARGGEILIPCQ 441
Query: 472 FFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNE 531
+P + W KG + ++ + +GTL I + G YTC A N +G A +
Sbjct: 442 PRAAPKAVVLWSKGTE-ILVNSSRVTVTPDGTLIIRNISRSDEGKYTCFAENFMGKANST 500
Query: 532 VHLEIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDE----- 586
L ++D T I P A + G ++ +C HD T+ LT W D+ + D+
Sbjct: 501 GILSVRDATKITLAPSSADINLGDNLTLQCHASHDPTMDLTFTWTLDDFPIDFDKPGGHY 560
Query: 587 RFTVDKD---HLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVDVPNPPFDLELTDQL 643
R T K+ L + + G YTC+A T +DS S A + V P PP + + D
Sbjct: 561 RRTNVKETIGDLTILNAQLRHGGKYTCMAQTVVDSASKEATVLVRGPPGPPGGVVVRDIG 620
Query: 644 DKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWH----HQTEVSGTQTTAQ-LKLSPY 698
D ++QLSW+ G DN+SPI K+ ++ G W + + G TAQ L L+P+
Sbjct: 621 DTTIQLSWSRGFDNHSPIAKYTLQARTP--PAGKWKQVRTNPANIEGNAETAQVLGLTPW 678
Query: 699 VNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFE 758
++Y FRV+A N +G PS S + T+ + P P+ + G G P L++ W P++
Sbjct: 679 MDYEFRVIASNILGTGEPSGPSSKIRTREAAPSVAPSGLSGGGGAPGELIVNWTPMSREY 738
Query: 759 SNGPGLQYKVSWRQKDGDDEWTSVVVANVSKYIVSGTPT---FVPYLIKVQALNDMGFAP 815
NG G Y +S+R++ T+ V ++Y V + + P+ +K+++ N G P
Sbjct: 739 QNGDGFGYLLSFRRQGSTHWQTARVPGADAQYFVYSNESVRPYTPFEVKIRSYNRRGDGP 798
Query: 816 EPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSS 875
E + +S E+ P VAP V V+S+ V W+PV + + G L GY I YWK
Sbjct: 799 ESLTALVYSAEEEPRVAPTKVWAKGVSSSEMNVTWEPVQ-QDMNGILLGYEIRYWKAGDK 857
Query: 876 SKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGV 935
R + G T + GL P + Y + VR N G GPASP T +
Sbjct: 858 EAAADR------VRTAGLDTSARVSGLHPNTKYHVTVRAYNRAGTGPASPSANATTMKPP 911
Query: 936 PSAPSSLKIVNPTLDSLTLEWDP--PSHPNGILTEYTLKYQ 974
P P + SL+++WDP P +T Y + YQ
Sbjct: 912 PRRPPGNISWTFSSSSLSIKWDPVVPFRNESAVTGYKMLYQ 952
Score = 89.7 bits (221), Expect = 1e-17
Identities = 104/419 (24%), Positives = 163/419 (38%), Gaps = 60/419 (14%)
Query: 40 PTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLI 99
P+I + P + + + ++C A G P P W + +D ++ P T
Sbjct: 239 PSIKARFPAETYALVGQQVTLECFAFGNPVPRIKWRK------VDG----SLSPQWTTAE 288
Query: 100 INIMSEGKAETYEGVYQCTARNERGA-AVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLV 158
+ + EG Y+C A N +G V I+V+ P W K + G +L
Sbjct: 289 PTLQIPSVSFEDEGTYECEAENSKGRDTVQGRIIVQ--AQPEWLK-VISDTEADIGSNLR 345
Query: 159 LPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNH 218
C G P P + W+ N + L RV + L GDL FS + ED+ Y C A H
Sbjct: 346 WGC-AAAGKPRPTVRWLRNG-EPLASQNRV-EVLAGDLRFSKLSLEDSGM-YQCVAENKH 401
Query: 219 TQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEELR 278
TI ++V+ ++ D R P L P R
Sbjct: 402 -GTIYASAELAVQALAPD--------------------FRLNPVRRLIPAA--------R 432
Query: 279 GNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKN 338
G + + C P ++ W+K +L + V + TL I ++S +D G Y C A+N
Sbjct: 433 GGEILIPCQPRAAPKAVVLWSKGTEILVNSSRVTVTPDGTLIIRNISRSDEGKYTCFAEN 492
Query: 339 ALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRI--SWLTNGVPIE 396
+G + T + V+ A AP + ++ G++ TL C A+ +P + +W + PI+
Sbjct: 493 FMGKANSTGILSVRDATKITLAPSSADINLGDNLTLQCHASHDPTMDLTFTWTLDDFPID 552
Query: 397 IAPDDPS--------RKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEP 447
D P ++ GD I N Q R Y C A A V V P
Sbjct: 553 F--DKPGGHYRRTNVKETIGDLTIL-NAQLRHGGKYTCMAQTVVDSASKEATVLVRGPP 608
Score = 58.9 bits (141), Expect = 3e-08
Identities = 84/373 (22%), Positives = 137/373 (36%), Gaps = 78/373 (20%)
Query: 35 DLVQPPTITQQSPK------DYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPL 88
D VQ I Q P+ D D N+ C A GKP P+ W RNG +PL
Sbjct: 315 DTVQGRIIVQAQPEWLKVISDTEADIGSNLRWGCAAAGKPRPTVRWLRNG-------EPL 367
Query: 89 VTMKPGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEP 148
+ L ++ + G+YQC A N+ G ++ + + +P + +L P
Sbjct: 368 ASQN-RVEVLAGDLRFSKLSLEDSGMYQCVAENKHGTIYASAELAVQALAPDF---RLNP 423
Query: 149 ----ITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPE 204
I G +++PC+P P ++ W + + L S RV+ +G L N+
Sbjct: 424 VRRLIPAARGGEILIPCQPR-AAPKAVVLWSKGT-EILVNSSRVTVTPDGTLIIRNISRS 481
Query: 205 DTREDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTF 264
D + Y C+A N +SV+ D T+A + +D
Sbjct: 482 DEGK-YTCFAE-NFMGKANSTGILSVR----DATKITLAPSSADINL------------- 522
Query: 265 LTPEGNASNKEELRGNVLSLECIAEGLPTP--IIYWAKEDGMLP-------KNRTVYKNF 315
G+ L+L+C A PT W +D + RT K
Sbjct: 523 --------------GDNLTLQCHASHDPTMDLTFTWTLDDFPIDFDKPGGHYRRTNVKET 568
Query: 316 EKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLI 375
L I++ G Y C+A+ + + +V V+ PG G ++
Sbjct: 569 IGDLTILNAQLRHGGKYTCMAQTVVDSASKEATVLVRG-------------PPGPPGGVV 615
Query: 376 CRANGNPKPRISW 388
R G+ ++SW
Sbjct: 616 VRDIGDTTIQLSW 628
Score = 56.6 bits (135), Expect = 1e-07
Identities = 61/271 (22%), Positives = 105/271 (38%), Gaps = 33/271 (12%)
Query: 367 SPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQC 426
S E L CRA +P W NG +++ P + + G+ +I + + + + VYQC
Sbjct: 52 STEEQVLLACRARASPPATYRWKMNGTEMKLEPGSRHQLVGGNLVIMNPTKAQDAGVYQC 111
Query: 427 NASNEYGYLLAN------AFVNVLAEPPRILTPANTLYQVI--ANRPALLDCAFFGSPLP 478
ASN G +++ F+ ++ R A+ + V+ N PA P
Sbjct: 112 LASNPVGTVVSREAILRFGFLQEFSKEERDPVKAHEGWGVMLPCNPPA-------HYPGL 164
Query: 479 TIEWFKGAKGSALHED--IYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEV---- 532
+ W + + D +V G L I G Y+C+A + + + V
Sbjct: 165 SYRWLLNEFPNFIPTDGRHFVSQTTGNLYIARTNASDLGNYSCLATSHMDFSTKSVFSKF 224
Query: 533 ---HLEIKD-----PTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPS 584
+L +D P+ + P G V+ EC + + W K + L
Sbjct: 225 AQLNLAAEDTRLFAPSIKARFPAETYALVGQQVTLECFAFGNPV--PRIKWRKVDGSL-- 280
Query: 585 DERFTVDKDHLVVADVSDDDSGTYTCVANTT 615
++T + L + VS +D GTY C A +
Sbjct: 281 SPQWTTAEPTLQIPSVSFEDEGTYECEAENS 311
>gi|75709184 contactin 3 [Homo sapiens]
Length = 1028
Score = 374 bits (960), Expect = e-103
Identities = 285/961 (29%), Positives = 425/961 (44%), Gaps = 68/961 (7%)
Query: 21 LFLCQMISALEVPLDLVQPPTITQQSPKDYIIDPREN-IVIQCEAKGKPPPSFSWTRNGT 79
L L I L L L P I + S + + + I + CEA+G P P + W NG+
Sbjct: 8 LILLSFIGCLGGELLLQGPVFIKEPSNSIFPVGSEDKKITLHCEARGNPSPHYRWQLNGS 67
Query: 80 HFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSP 139
DID K G L++ I +T G YQC A N G VS ++ +
Sbjct: 68 --DIDMSMEHRYKLNGGNLVV-INPNRNWDT--GTYQCFATNSLGTIVSREAKLQFAYLE 122
Query: 140 LWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQ--SERVSQGLNGDLY 197
+ + ++++ GQ +VL C PP W+ N + + S R G LY
Sbjct: 123 NFKTKMRSTVSVREGQGVVLLCGPPPHSGELSYAWIFNEYPSFVEEDSRRFVSQETGHLY 182
Query: 198 FSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSS 257
S V P D +Y C T P + + S + + Y K
Sbjct: 183 ISKVEPSDV-GNYTCVVTSMVTNARVLGSPTPLVLRSDGVMGE-----------YEPKIE 230
Query: 258 RERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEK 317
+ P T +G+ + LEC A G P P I W + DG+ ++ + F
Sbjct: 231 VQFPETL----------PAAKGSTVKLECFALGNPIPQINWRRSDGLPFSSKIKLRKFSG 280
Query: 318 TLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICR 377
L+I + + D+G+Y+CIA+N+ G + A P+W+ +++ ++ + CR
Sbjct: 281 VLEIPNFQQEDAGSYECIAENSRGKNVARGRLTYYAKPHWVQLIKDVEIAVEDSLYWECR 340
Query: 378 ANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLA 437
A+G PKP WL NG + + + +I+ + SN+ S ++QC A N++G + +
Sbjct: 341 ASGKPKPSYRWLKNGAALVL---EERTQIENGALTISNLSVTDSGMFQCIAENKHGLVYS 397
Query: 438 NAFVNVLAEPPRI-LTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIY 496
+A + V+A P P L QV LDC SP W KG HE I
Sbjct: 398 SAELKVVASAPDFSKNPMKKLVQVQVGSLVSLDCKPRASPRALSSWKKGDVSVQEHERIS 457
Query: 497 VLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSM 556
+L++ G L+I K GTYTC+A N+ G A HL + +PT I P V G
Sbjct: 458 LLNDGG-LKIANVTKADAGTYTCMAENQFGKANGTTHLVVTEPTRITLAPSNMDVSVGES 516
Query: 557 VSFECKVKHDHTLSLTVLW-----LKDNRELPS--DERFTVDKDHLVVADVSDDDSGTYT 609
V C+V+HD L + W L D ++ S ++ L++ ++ SG Y
Sbjct: 517 VILPCQVQHDPLLDIIFTWYFNGALADFKKDGSHFEKVGGSSSGDLMIRNIQLKHSGKYV 576
Query: 610 CVANTTLDSVSASAVLSVVDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYE 669
C+ T +DSVS++A L V P PP ++++ + D + QLSW G DN+SP+ + I+
Sbjct: 577 CMVQTGVDSVSSAADLIVRGSPGPPENVKVDEITDTTAQLSWKEGKDNHSPVISYSIQAR 636
Query: 670 DAMHKPGLWHHQTEV-----SGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEASEQYL 724
W T V T T ++L+P+V Y FRV+A N IG PS SE+
Sbjct: 637 TPFSVG--WQTVTTVPEVIDGKTHTATVVELNPWVEYEFRVVASNKIGGGEPSLPSEKVR 694
Query: 725 TKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDEWTSVVV 784
T+ + P+ P+ V G G LVITW P+ NG G Y V++R G W VV
Sbjct: 695 TEEAVPEVPPSEVNGGGGSRSELVITWDPVPEELQNGEGFGYVVAFRPL-GVTTWIQTVV 753
Query: 785 A--NVSKYIV--SGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNV 840
+ +Y+ + PY +KV N+ G P V S E+ P VAP V N
Sbjct: 754 TSPDTPRYVFRNESIVPYSPYEVKVGVYNNKGEGPFSPVTTVFSAEEEPTVAPSQVSANS 813
Query: 841 VNSTLAEVHWDPVPLKSIRGHLQGYRIYYW----KTQSSSKRNRRHIEKKILTFQGSKTH 896
++S+ EV W+ +P K GHL GY + YW K +SSSK + G++T
Sbjct: 814 LSSSEIEVSWNTIPWKLSNGHLLGYEVRYWNGGGKEESSSK----------MKVAGNETS 863
Query: 897 GMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEW 956
L GL+ Y VR N G GP S T + PS P + N T + L W
Sbjct: 864 ARLRGLKSNLAYYTAVRAYNSAGAGPFSATVNVTTKKTPPSQPPGNVVWNATDTKVLLNW 923
Query: 957 D 957
+
Sbjct: 924 E 924
Score = 144 bits (364), Expect = 4e-34
Identities = 181/767 (23%), Positives = 310/767 (40%), Gaps = 103/767 (13%)
Query: 319 LQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAP-----------------YWITAP 361
L I V +D GNY C+ + + + RV +P + P
Sbjct: 181 LYISKVEPSDVGNYTCVVTSMV------TNARVLGSPTPLVLRSDGVMGEYEPKIEVQFP 234
Query: 362 QNLVLSPGEDGTLICRANGNPKPRISWL-TNGVPIEIAPDDPSRKIDGDTIIFSNVQERS 420
+ L + G L C A GNP P+I+W ++G+P + RK G + N Q+
Sbjct: 235 ETLPAAKGSTVKLECFALGNPIPQINWRRSDGLPF--SSKIKLRKFSG-VLEIPNFQQED 291
Query: 421 SAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTI 480
+ Y+C A N G +A + A+P + + ++ +C G P P+
Sbjct: 292 AGSYECIAENSRGKNVARGRLTYYAKPHWVQLIKDV--EIAVEDSLYWECRASGKPKPSY 349
Query: 481 EWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPT 540
W K L E + ENG L I +G + C+A NK G+ + L++
Sbjct: 350 RWLKNGAALVLEERTQI--ENGALTISNLSVTDSGMFQCIAENKHGLVYSSAELKV---- 403
Query: 541 WIVKQPEYAV--------VQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDK 592
+ P+++ VQ GS+VS +CK + + W K + + ER ++
Sbjct: 404 -VASAPDFSKNPMKKLVQVQVGSLVSLDCKPRASPRALSS--WKKGDVSVQEHERISLLN 460
Query: 593 DH-LVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVD---VPNPPFDLELTDQLDKSVQ 648
D L +A+V+ D+GTYTC+A + + L V + + P +++++ + +SV
Sbjct: 461 DGGLKIANVTKADAGTYTCMAENQFGKANGTTHLVVTEPTRITLAPSNMDVS--VGESVI 518
Query: 649 LSWTPGDDNNSPITKFIIE--YEDAM---HKPGLWHHQTEVSGTQTTAQLKLSPYVNYSF 703
L P + P+ I + A+ K G H +V G+ + + + + +S
Sbjct: 519 L---PCQVQHDPLLDIIFTWYFNGALADFKKDG--SHFEKVGGSSSGDLMIRNIQLKHSG 573
Query: 704 RVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPG 763
+ + + G S A++ + + P +N E + ++WK G +++ P
Sbjct: 574 KYVCMVQTGVDSVSSAADLIVRGSPGPPENVKVDEITDTTAQ---LSWK--EGKDNHSPV 628
Query: 764 LQYKVSWRQKDGDDEWTSVVVANV------SKYIVSGTPTFVPYLIKVQALNDMGFAPEP 817
+ Y + R T V V + +V P +V Y +V A N +G EP
Sbjct: 629 ISYSIQARTPFSVGWQTVTTVPEVIDGKTHTATVVELNP-WVEYEFRVVASNKIG-GGEP 686
Query: 818 AVVMG--HSGEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYY------ 869
++ + E +P V P V + + + WDPVP + G GY + +
Sbjct: 687 SLPSEKVRTEEAVPEVPPSEVNGGGGSRSELVITWDPVPEELQNGEGFGYVVAFRPLGVT 746
Query: 870 -W-KTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASP-D 926
W +T +S R++ + + P+S Y + V V N KGEGP SP
Sbjct: 747 TWIQTVVTSPDTPRYVFRN-------------ESIVPYSPYEVKVGVYNNKGEGPFSPVT 793
Query: 927 RVFNTPEGVPSAPSSLKIVNPTLDSLTLEWD--PPSHPNGILTEYTLKYQPINSTHELGP 984
VF+ E APS + + + + + W+ P NG L Y ++Y E
Sbjct: 794 TVFSAEEEPTVAPSQVSANSLSSSEIEVSWNTIPWKLSNGHLLGYEVRYWNGGGKEESSS 853
Query: 985 LVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEEAVTT 1031
+K+ N+T L+ L + Y A SAG+G VTT
Sbjct: 854 --KMKVAGNETSARLRGLKSNLAYYTAVRAYNSAGAGPFSATVNVTT 898
>gi|7657359 contactin 5 isoform long [Homo sapiens]
Length = 1100
Score = 362 bits (929), Expect = 1e-99
Identities = 273/942 (28%), Positives = 423/942 (44%), Gaps = 76/942 (8%)
Query: 45 QSPKDYII---DPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIIN 101
Q P D I + + + CE +G P PS+ W RNGT D++ D ++ GT II+
Sbjct: 103 QEPDDIIFPTDSDEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLIDGT--FIIS 160
Query: 102 IMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPC 161
SE K G YQC A N G+ +S ++ + ++ ++++ GQ +VL C
Sbjct: 161 NPSEAKDS---GHYQCLATNTVGSILSREATLQFAYLGNFSGRTRSAVSVREGQGVVLMC 217
Query: 162 RPPIGLPPPIIFWMDNSFQRL--PQSERVSQGLNGDLYFSNVLPEDTREDYICYAR--FN 217
PP P I W+ N F S R G+LY S V D YIC +
Sbjct: 218 SPPPHSPEIIYSWVFNEFPSFVAEDSRRFISQETGNLYISKVQTSDVGS-YICLVKNTVT 276
Query: 218 HTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEEL 277
+ + + P++++ ND + Y K P T
Sbjct: 277 NARVLSPPTPLTLR-------NDGVMGE------YEPKIEVHFPFTVTAA---------- 313
Query: 278 RGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAK 337
+G + +EC A G P P I W K +G +P + K+ + L+I +V D+G Y+C A+
Sbjct: 314 KGTTVKMECFALGNPVPTITWMKVNGYIPSKARLRKS-QAVLEIPNVQLDDAGIYECRAE 372
Query: 338 NALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEI 397
N+ G ++V P+W+ + L G C+A G P+P WL NGVP+
Sbjct: 373 NSRGKNSFRGQLQVYTYPHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPL-- 430
Query: 398 APDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRI-LTPANT 456
+P ++G ++ NV + + +YQC A N+YG + A+A + +LA P L
Sbjct: 431 SPQSRVEMVNG-VLMIHNVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFALNQLKK 489
Query: 457 LYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGT 516
V ++ +++C GSP PTI W KG + ++ I +L + G+L I A K G
Sbjct: 490 TIIVTKDQEVVIECKPQGSPKPTISWKKGDRAVRENKRIAILPD-GSLRILNASKSDEGK 548
Query: 517 YTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWL 576
Y C N G A+ L +K+PT I P+ + G + CK HD +L +T W
Sbjct: 549 YVCRGENVFGSAEIIASLSVKEPTRIELTPKRTELTVGESIVLNCKAIHDASLDVTFYWT 608
Query: 577 KDNRELPSDE--------RFTVDKDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVV 628
+ + +E R L++ ++ +G Y C TT DSVS A L V
Sbjct: 609 LKGQPIDFEEEGGHFESIRAQASSADLMIRNILLMHAGRYGCRVQTTADSVSDEAELLVR 668
Query: 629 DVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQTE----- 683
P PP + + + + + LSW+P DN+SPI+ + ++ P QT
Sbjct: 669 GPPGPPGIVIVEEITESTATLSWSPAADNHSPISSYNLQ----ARSPFSLGWQTVKTVPE 724
Query: 684 -VSGTQTTAQ-LKLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLG 741
++G +A + L+P+V Y FRV+A N IG PS S T + P PT V G
Sbjct: 725 IITGDMESAMAVDLNPWVEYEFRVVATNPIGTGDPSTPSRMIRTNEAVPKTAPTNVSGRS 784
Query: 742 SEPDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDEWTSVVV--ANVSKYIV--SGTPT 797
LVI W+P++ NG G Y V++R +G W +V + SK+I P
Sbjct: 785 GRRHELVIAWEPVSEEFQNGEGFGYIVAFR-PNGTRGWKEKMVTSSEASKFIYRDESVPP 843
Query: 798 FVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKS 857
P+ +KV N+ G P +V+ S E P AP +V+ V+ + V W + K
Sbjct: 844 LTPFEVKVGVYNNKGDGPFSQIVVICSAEGEPSAAPTDVKATSVSVSEILVAWKHI--KE 901
Query: 858 IRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNG 917
G QG+ + YWK + + +G+++ +L GLE + Y VR NG
Sbjct: 902 SLGRPQGFEVGYWKDMEQED------TAETVKTRGNESFVILTGLEGNTLYHFTVRAYNG 955
Query: 918 KGEGPASPDRVFNTPEGVPS-APSSLKIVNPTLDSLTLEWDP 958
G GP S + T + PS APS+L+ ++L W+P
Sbjct: 956 AGYGPPSSEVSATTKKSPPSQAPSNLRWEQQG-SQVSLGWEP 996
Score = 45.8 bits (107), Expect = 2e-04
Identities = 35/130 (26%), Positives = 60/130 (46%), Gaps = 14/130 (10%)
Query: 36 LVQPPTIT-QQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPG 94
L PT Q K I+ + +VI+C+ +G P P+ SW + + ++ + + P
Sbjct: 476 LASAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISWKKGDR--AVRENKRIAILPD 533
Query: 95 TGTLIINIMSEGKAETYEGVYQCTARNERGAA--VSNNIVVRPSRSPLWTKEKLEPITLQ 152
I+N +++ EG Y C N G+A +++ V P+R L K L
Sbjct: 534 GSLRILN-----ASKSDEGKYVCRGENVFGSAEIIASLSVKEPTRIELTPKR----TELT 584
Query: 153 SGQSLVLPCR 162
G+S+VL C+
Sbjct: 585 VGESIVLNCK 594
>gi|28373129 contactin 5 isoform short [Homo sapiens]
Length = 1026
Score = 362 bits (929), Expect = 1e-99
Identities = 273/942 (28%), Positives = 423/942 (44%), Gaps = 76/942 (8%)
Query: 45 QSPKDYII---DPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIIN 101
Q P D I + + + CE +G P PS+ W RNGT D++ D ++ GT II+
Sbjct: 29 QEPDDIIFPTDSDEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLIDGT--FIIS 86
Query: 102 IMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPC 161
SE K G YQC A N G+ +S ++ + ++ ++++ GQ +VL C
Sbjct: 87 NPSEAKDS---GHYQCLATNTVGSILSREATLQFAYLGNFSGRTRSAVSVREGQGVVLMC 143
Query: 162 RPPIGLPPPIIFWMDNSFQRL--PQSERVSQGLNGDLYFSNVLPEDTREDYICYAR--FN 217
PP P I W+ N F S R G+LY S V D YIC +
Sbjct: 144 SPPPHSPEIIYSWVFNEFPSFVAEDSRRFISQETGNLYISKVQTSDVGS-YICLVKNTVT 202
Query: 218 HTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEEL 277
+ + + P++++ ND + Y K P T
Sbjct: 203 NARVLSPPTPLTLR-------NDGVMGE------YEPKIEVHFPFTVTAA---------- 239
Query: 278 RGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAK 337
+G + +EC A G P P I W K +G +P + K+ + L+I +V D+G Y+C A+
Sbjct: 240 KGTTVKMECFALGNPVPTITWMKVNGYIPSKARLRKS-QAVLEIPNVQLDDAGIYECRAE 298
Query: 338 NALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEI 397
N+ G ++V P+W+ + L G C+A G P+P WL NGVP+
Sbjct: 299 NSRGKNSFRGQLQVYTYPHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPL-- 356
Query: 398 APDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRI-LTPANT 456
+P ++G ++ NV + + +YQC A N+YG + A+A + +LA P L
Sbjct: 357 SPQSRVEMVNG-VLMIHNVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFALNQLKK 415
Query: 457 LYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGT 516
V ++ +++C GSP PTI W KG + ++ I +L + G+L I A K G
Sbjct: 416 TIIVTKDQEVVIECKPQGSPKPTISWKKGDRAVRENKRIAILPD-GSLRILNASKSDEGK 474
Query: 517 YTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWL 576
Y C N G A+ L +K+PT I P+ + G + CK HD +L +T W
Sbjct: 475 YVCRGENVFGSAEIIASLSVKEPTRIELTPKRTELTVGESIVLNCKAIHDASLDVTFYWT 534
Query: 577 KDNRELPSDE--------RFTVDKDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVV 628
+ + +E R L++ ++ +G Y C TT DSVS A L V
Sbjct: 535 LKGQPIDFEEEGGHFESIRAQASSADLMIRNILLMHAGRYGCRVQTTADSVSDEAELLVR 594
Query: 629 DVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQTE----- 683
P PP + + + + + LSW+P DN+SPI+ + ++ P QT
Sbjct: 595 GPPGPPGIVIVEEITESTATLSWSPAADNHSPISSYNLQ----ARSPFSLGWQTVKTVPE 650
Query: 684 -VSGTQTTAQ-LKLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLG 741
++G +A + L+P+V Y FRV+A N IG PS S T + P PT V G
Sbjct: 651 IITGDMESAMAVDLNPWVEYEFRVVATNPIGTGDPSTPSRMIRTNEAVPKTAPTNVSGRS 710
Query: 742 SEPDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDEWTSVVV--ANVSKYIV--SGTPT 797
LVI W+P++ NG G Y V++R +G W +V + SK+I P
Sbjct: 711 GRRHELVIAWEPVSEEFQNGEGFGYIVAFR-PNGTRGWKEKMVTSSEASKFIYRDESVPP 769
Query: 798 FVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKS 857
P+ +KV N+ G P +V+ S E P AP +V+ V+ + V W + K
Sbjct: 770 LTPFEVKVGVYNNKGDGPFSQIVVICSAEGEPSAAPTDVKATSVSVSEILVAWKHI--KE 827
Query: 858 IRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNG 917
G QG+ + YWK + + +G+++ +L GLE + Y VR NG
Sbjct: 828 SLGRPQGFEVGYWKDMEQED------TAETVKTRGNESFVILTGLEGNTLYHFTVRAYNG 881
Query: 918 KGEGPASPDRVFNTPEGVPS-APSSLKIVNPTLDSLTLEWDP 958
G GP S + T + PS APS+L+ ++L W+P
Sbjct: 882 AGYGPPSSEVSATTKKSPPSQAPSNLRWEQQG-SQVSLGWEP 922
Score = 45.8 bits (107), Expect = 2e-04
Identities = 35/130 (26%), Positives = 60/130 (46%), Gaps = 14/130 (10%)
Query: 36 LVQPPTIT-QQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPG 94
L PT Q K I+ + +VI+C+ +G P P+ SW + + ++ + + P
Sbjct: 402 LASAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISWKKGDR--AVRENKRIAILPD 459
Query: 95 TGTLIINIMSEGKAETYEGVYQCTARNERGAA--VSNNIVVRPSRSPLWTKEKLEPITLQ 152
I+N +++ EG Y C N G+A +++ V P+R L K L
Sbjct: 460 GSLRILN-----ASKSDEGKYVCRGENVFGSAEIIASLSVKEPTRIELTPKR----TELT 510
Query: 153 SGQSLVLPCR 162
G+S+VL C+
Sbjct: 511 VGESIVLNCK 520
>gi|28373122 contactin 4 isoform a precursor [Homo sapiens]
Length = 1026
Score = 358 bits (919), Expect = 2e-98
Identities = 299/1049 (28%), Positives = 451/1049 (42%), Gaps = 89/1049 (8%)
Query: 20 ILFLCQMISALEVPLDLVQPPTITQQSPKDYIIDPRENIV-IQCEAKGKPPPSFSWTRNG 78
+L L I L L P I + SP + +D E V + CE KG P P W NG
Sbjct: 7 LLVLQSFILCLADDSTLHGPIFIQEPSPVMFPLDSEEKKVKLNCEVKGNPKPHIRWKLNG 66
Query: 79 THFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRS 138
T D D ++ G+ L+IN + K + G YQCTA N G VS ++ +
Sbjct: 67 TDVDTGMDFRYSVVEGS--LLIN--NPNKTQD-AGTYQCTATNSFGTIVSREAKLQFAYL 121
Query: 139 PLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYF 198
+ ++++ GQ +VL C PP W+ N + + R G+LY
Sbjct: 122 DNFKTRTRSTVSVRRGQGMVLLCGPPPHSGELSYAWIFNEYPSYQDNRRFVSQETGNLYI 181
Query: 199 SNVLPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSR 258
+ V D +Y C T T+ + + + ND + Y K
Sbjct: 182 AKVEKSDVG-NYTCVV----TNTVTNHKVLGPPTPLILR-NDGVMGE------YEPKIEV 229
Query: 259 ERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKT 318
+ P T T +G + LEC A G P P I W + DG +
Sbjct: 230 QFPETVPTA----------KGATVKLECFALGNPVPTIIWRRADGKPIARKARRHKSNGI 279
Query: 319 LQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRA 378
L+I + + D+G Y+C+A+N+ G + A P WI ++ ++ E+ C+A
Sbjct: 280 LEIPNFQQEDAGLYECVAENSRGKNVARGQLTFYAQPNWIQKINDIHVAMEENVFWECKA 339
Query: 379 NGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLAN 438
NG PKP WL NG P+ + D +I+ T+ + V + +YQC A N++G + +N
Sbjct: 340 NGRPKPTYKWLKNGEPL-LTRD--RIQIEQGTLNITIVNLSDAGMYQCLAENKHGVIFSN 396
Query: 439 AFVNVLAEPP---RILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDI 495
A ++V+A P R L TL +V +++C SP P W KG +E I
Sbjct: 397 AELSVIAVGPDFSRTLLKRVTLVKV--GGEVVIECKPKASPKPVYTWKKGRDILKENERI 454
Query: 496 YVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGS 555
+ E+G L I K G+YTC+A N G A + +L +KDPT ++ P V G
Sbjct: 455 -TISEDGNLRIINVTKSDAGSYTCIATNHFGTASSTGNLVVKDPTRVMVPPSSMDVTVGE 513
Query: 556 MVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH------------LVVADVSDD 603
+ C+V HDH+L + W + + D D DH L++ ++
Sbjct: 514 SIVLPCQVTHDHSLDIVFTWSFNGHLIDFDR----DGDHFERVGGQDSAGDLMIRNIQLK 569
Query: 604 DSGTYTCVANTTLDSVSASAVLSVVDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITK 663
+G Y C+ T++D +SA+A L V P PP + + + D + QLSW PG DN+SPIT
Sbjct: 570 HAGKYVCMVQTSVDRLSAAADLIVRGPPGPPEAVTIDEITDTTAQLSWRPGPDNHSPITM 629
Query: 664 FIIEYEDAMHKPGLWHHQTEV-----SGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSE 718
++I+ W + V T T + L+P+V Y FR +A N IG PS
Sbjct: 630 YVIQARTPFSVG--WQAVSTVPELIDGKTFTATVVGLNPWVEYEFRTVAANVIGIGEPSR 687
Query: 719 ASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDE 778
SE+ T+ + P+ P V G G LVITW+ + NG G Y V++R G
Sbjct: 688 PSEKRRTEEALPEVTPANVSGGGGSKSELVITWETVPEELQNGRGFGYVVAFRPY-GKMI 746
Query: 779 W--TSVVVANVSKYIV--SGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPG 834
W T + A+ S+Y+ F P+ +KV N+ G P + +S E+ P P
Sbjct: 747 WMLTVLASADASRYVFRNESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPA 806
Query: 835 NVRVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSK 894
++ +++T EV W PL+ RG +QGY + YW+ + + R KI T G++
Sbjct: 807 SIFARSLSATDIEVFW-ASPLEKNRGRIQGYEVKYWRHEDKEENAR-----KIRTV-GNQ 859
Query: 895 THGMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTL 954
T + L+ Y L V+ N G GP+S T + PS P I N + + L
Sbjct: 860 TSTKITNLKGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKIIL 919
Query: 955 EWDP------PSHPNGILTEYTLKYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRY 1008
WD S G Y Q S I NKT L +L F Y
Sbjct: 920 NWDQVKALDNESEVKGYKVLYRWNRQSSTSV----------IETNKTSVEL-SLPFDEDY 968
Query: 1009 KFYFYAQTSAGSGSQITEEAVTTVDEAMA 1037
+ G GS + + + A A
Sbjct: 969 IIEIKPFSDGGDGSSSEQIRIPKISNAYA 997
>gi|7657361 contactin 6 [Homo sapiens]
Length = 1028
Score = 337 bits (865), Expect = 3e-92
Identities = 270/944 (28%), Positives = 402/944 (42%), Gaps = 63/944 (6%)
Query: 36 LVQPPTITQQSPKDYIID---PRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMK 92
L+ P TQ+ P D I + +++ C A G P P + W +NGT DID +
Sbjct: 22 LLSRPIFTQE-PHDVIFPLDLSKSEVILNCAANGYPSPHYRWKQNGT--DIDFTMSYHYR 78
Query: 93 PGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQ 152
G+L IN + G+YQC A N G +S ++ + + + ++++
Sbjct: 79 LDGGSLAIN---SPHTDQDIGMYQCLATNLLGTILSRKAKLQFAYIEDFETKTRSTVSVR 135
Query: 153 SGQSLVLPCRPPIGLPPPIIFWM--DNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDY 210
GQ +VL C PP W DN + R G+LY + V P D +Y
Sbjct: 136 EGQGVVLLCGPPPHFGDLSYAWTFNDNPLYVQEDNRRFVSQETGNLYIAKVEPSDVG-NY 194
Query: 211 ICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGN 270
C+ Q Q P + + D + Y K P T
Sbjct: 195 TCFITNKEAQRSVQGPPTPLV-----QRTDGVMGE------YEPKIEVRFPETI------ 237
Query: 271 ASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSG 330
+ + + + LEC A G P P I W + DG + Y + L+I + + D G
Sbjct: 238 ----QAAKDSSVKLECFALGNPVPDISWRRLDGSPLPGKVKYSKSQAILEIPNFQQEDEG 293
Query: 331 NYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLT 390
Y+CIA N G + A P W QN LS ++ C+A+G P P +WL
Sbjct: 294 FYECIASNLRGRNLAKGQLIFYAPPEWEQKIQNTHLSIYDNLLWECKASGKPNPWYTWLK 353
Query: 391 NGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRI 450
NG E + +I+ T+I + + S VYQC A N+Y + ANA + VLA P
Sbjct: 354 NG---ERLNPEERIQIENGTLIITMLNVSDSGVYQCAAENKYQIIYANAELRVLASAPDF 410
Query: 451 L-TPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVA 509
+P V ++ C P I W +G + + I++L E+G+L+I
Sbjct: 411 SKSPVKKKSFVQVGGDIVIGCKPNAFPRAAISWKRGTETLRQSKRIFLL-EDGSLKIYNI 469
Query: 510 QKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTL 569
+ G+YTC+A N+ G AKN L +K+ T I P V G + C+V HD ++
Sbjct: 470 TRSDAGSYTCIATNQFGTAKNTGSLIVKERTVITVPPSKMDVTVGESIVLPCQVSHDPSI 529
Query: 570 SLTVLWLKDN------RELPSDERFTVDK-DHLVVADVSDDDSGTYTCVANTTLDSVSAS 622
+ +W + + + ER + L++ ++ SG Y C TTL+S+SA
Sbjct: 530 EVVFVWFFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQLHHSGKYLCTVQTTLESLSAV 589
Query: 623 AVLSVVDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQT 682
A + V P PP D+++ D + QLSW G DNNSPI F I+ W
Sbjct: 590 ADIIVRGPPGPPEDVQVEDISSTTSQLSWRAGPDNNSPIQIFTIQTRTPFSVG--WQAVA 647
Query: 683 EV-----SGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAV 737
V T + LSP+V Y FRV+A NSIG PSE SE TKAS P P +
Sbjct: 648 TVPEILNGKTYNATVVGLSPWVEYEFRVVAGNSIGIGEPSEPSELLRTKASVPVVAPVNI 707
Query: 738 EGLGSEPDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDEWTSVVVANVSK----YIVS 793
G G LVITW+ + NG G Y + +R G W+ V++V Y
Sbjct: 708 HGGGGSRSELVITWESIPEELQNGEGFGYIIMFRPV-GSTTWSKEKVSSVESSRFVYRNE 766
Query: 794 GTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPV 853
P+ +KV N+ G V + +SGED P +AP + +++ EV W+ +
Sbjct: 767 SIIPLSPFEVKVGVYNNEGEGSLSTVTIVYSGEDEPQLAPRGTSLQSFSASEMEVSWNAI 826
Query: 854 PLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVR 913
G + GY + YW S + + G+ T + GL+ + Y +VR
Sbjct: 827 AWNRNTGRVLGYEVLYWTDDSKESMIGK------IRVSGNVTTKNITGLKANTIYFASVR 880
Query: 914 VVNGKGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWD 957
N G GP+SP T + PS P + T L L W+
Sbjct: 881 AYNTAGTGPSSPPVNVTTKKSPPSQPPANIAWKLTNSKLCLNWE 924
Score = 83.6 bits (205), Expect = 1e-15
Identities = 103/437 (23%), Positives = 180/437 (41%), Gaps = 58/437 (13%)
Query: 18 PLILFLCQMISALEVPLDLVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRN 77
PL+ ++ E +++ P TI Q+ KD ++ ++C A G P P SW R
Sbjct: 213 PLVQRTDGVMGEYEPKIEVRFPETI--QAAKD------SSVKLECFALGNPVPDISWRR- 263
Query: 78 GTHFDIDKDPLV-TMKPGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPS 136
+D PL +K I+ I + + + EG Y+C A N RG ++ ++ +
Sbjct: 264 -----LDGSPLPGKVKYSKSQAILEIPNFQQED--EGFYECIASNLRGRNLAKGQLIFYA 316
Query: 137 RSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDL 196
P W ++K++ L +L+ C+ G P P W+ N +RL ER+ Q NG L
Sbjct: 317 -PPEW-EQKIQNTHLSIYDNLLWECKAS-GKPNPWYTWLKNG-ERLNPEERI-QIENGTL 371
Query: 197 YFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKS 256
+ + D+ Y C A N Q I + V + D
Sbjct: 372 IITMLNVSDSGV-YQCAAE-NKYQIIYANAELRVLASAPD-----------------FSK 412
Query: 257 SRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFE 316
S + +F+ G+ + + C P I W + L +++ ++ +
Sbjct: 413 SPVKKKSFVQVGGD-----------IVIGCKPNAFPRAAISWKRGTETLRQSKRIFLLED 461
Query: 317 KTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLIC 376
+L+I +++ +D+G+Y CIA N G +T S+ VK P + ++ GE L C
Sbjct: 462 GSLKIYNITRSDAGSYTCIATNQFGTAKNTGSLIVKERTVITVPPSKMDVTVGESIVLPC 521
Query: 377 RANGNPKPRI--SWLTNGVPIEIAPDDPS-RKIDGDTI---IFSNVQERSSAVYQCNASN 430
+ + +P + W NG I++ +I G+++ + N+Q S Y C
Sbjct: 522 QVSHDPSIEVVFVWFFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQLHHSGKYLCTVQT 581
Query: 431 EYGYLLANAFVNVLAEP 447
L A A + V P
Sbjct: 582 TLESLSAVADIIVRGPP 598
Score = 35.4 bits (80), Expect = 0.32
Identities = 53/242 (21%), Positives = 91/242 (37%), Gaps = 12/242 (4%)
Query: 575 WLKDNRELPSDERFTVDKDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVDVPN-P 633
W K+ RF + ++ + G Y +L +V+ V S D P
Sbjct: 748 WSKEKVSSVESSRFVYRNESIIPLSPFEVKVGVYNNEGEGSLSTVTI--VYSGEDEPQLA 805
Query: 634 PFDLELTDQLDKSVQLSWTP--GDDNNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTA 691
P L +++SW + N + + + Y K + + VSG TT
Sbjct: 806 PRGTSLQSFSASEMEVSWNAIAWNRNTGRVLGYEVLYWTDDSKESMIG-KIRVSGNVTTK 864
Query: 692 QLK-LSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVIT 750
+ L Y V A N+ G PS TK S P + P + + L +
Sbjct: 865 NITGLKANTIYFASVRAYNTAGTG-PSSPPVNVTTKKSPPSQPPANIAWKLTN-SKLCLN 922
Query: 751 WKPLNGFESNGPGLQYKVSWRQKDGDDEWTSVVVANVSKYIVSGTPTFVPYLIKVQALND 810
W+ + E+ L YK+ +RQ + + + N S ++ P YLI+++ ++D
Sbjct: 923 WEHVKTMENESEVLGYKILYRQ-NRQSKTHILETNNTSAELL--VPFEEDYLIEIRTVSD 979
Query: 811 MG 812
G
Sbjct: 980 GG 981
>gi|28373117 contactin 1 isoform 1 precursor [Homo sapiens]
Length = 1018
Score = 312 bits (800), Expect = 1e-84
Identities = 261/948 (27%), Positives = 412/948 (43%), Gaps = 92/948 (9%)
Query: 58 IVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQC 117
+ + C A+ P P + W N D+ D + G L+IN + K G+Y C
Sbjct: 61 VSLNCRARASPFPVYKWRMNNGDVDLTSDRYSMVG---GNLVINNPDKQKDA---GIYYC 114
Query: 118 TARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIF-WMD 176
A N G S + + E+ + ++ G+ +VL C PP P + + W+
Sbjct: 115 LASNNYGMVRSTEATLSFGYLDPFPPEERPEVRVKEGKGMVLLCDPPYHFPDDLSYRWLL 174
Query: 177 NSFQ---RLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARF-NHTQTIQQKQPISVKV 232
N F + + VSQ NG+LY +NV D + +Y C+ + T+++ K + +
Sbjct: 175 NEFPVFITMDKRRFVSQ-TNGNLYIANVEASD-KGNYSCFVSSPSITKSVFSK---FIPL 229
Query: 233 ISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLP 292
I + E ++++ P + + L G ++LEC A G P
Sbjct: 230 IPIPE-----------------RTTKPYPADIVV---QFKDVYALMGQNVTLECFALGNP 269
Query: 293 TPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVK 352
P I W K +P + + L+I ++ D G Y+C A+N G H + V+
Sbjct: 270 VPDIRWRKVLEPMPSTAEISTS-GAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQ 328
Query: 353 AAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTII 412
A P W+ + + G D C A G P P I WL NG G+ +
Sbjct: 329 AFPEWVEHINDTEVDIGSDLYWPCVATGKPIPTIRWLKNGYAYH----------KGELRL 378
Query: 413 FSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRI-LTPANTLYQVIANRPALLDCA 471
+ +V ++ +YQC A N YG + ANA + +LA P + P +++C
Sbjct: 379 Y-DVTFENAGMYQCIAENTYGAIYANAELKILALAPTFEMNPMKKKILAAKGGRVIIECK 437
Query: 472 FFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNE 531
+P P W KG + ++ ++ E+G+LEI ++ G YTC A N G A +
Sbjct: 438 PKAAPKPKFSWSKGTEW-LVNSSRILIWEDGSLEINNITRNDGGIYTCFAENNRGKANST 496
Query: 532 VHLEIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLW------LKDNRE-LPS 584
L I DPT I+ P A + G + +C D L LT +W + N+E +
Sbjct: 497 GTLVITDPTRIILAPINADITVGENATMQCAASFDPALDLTFVWSFNGYVIDFNKENIHY 556
Query: 585 DERFTVDKD-HLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVDVPNPPFDLELTDQL 643
F +D + L++ + +G YTC A T +D+ SASA L V P PP L + D
Sbjct: 557 QRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNSSASADLVVRGPPGPPGGLRIEDIR 616
Query: 644 DKSVQLSWTPGDDNNSPITKFII--------EYEDAMHKPGLWHHQTEVSGTQTTAQ-LK 694
SV L+W+ G DN+SPI+K+ I +++DA P + + G A+ +
Sbjct: 617 ATSVALTWSRGSDNHSPISKYTIQTKTILSDDWKDAKTDPPI------IEGNMEAARAVD 670
Query: 695 LSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPL 754
L P++ Y FRV+A N++G+ PS S + T + P+ P+ V G G L ITW PL
Sbjct: 671 LIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGGGRNRELTITWAPL 730
Query: 755 NGFESNGPGLQYKVSWRQKDGDDEWTSVVVAN--VSKYIVSGTPTFVP---YLIKVQALN 809
+ G Y V+++ DG +EW V V N +Y V T P + +KV+A N
Sbjct: 731 SREYHYGNNFGYIVAFKPFDG-EEWKKVTVTNPDTGRY-VHKDETMSPSTAFQVKVKAFN 788
Query: 810 DMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYY 869
+ G P V + +S +D P AP V V V++S+ VHW+ V K + + Y+I Y
Sbjct: 789 NKGDGPYSLVAVINSAQDAPSEAPTEVGVKVLSSSEISVHWEHVLEKIV----ESYQIRY 844
Query: 870 WKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVF 929
W + R + + L L P + Y + V N G GP S
Sbjct: 845 WAAHDKEEAANR------VQVTSQEYSARLENLLPDTQYFIEVGACNSAGCGPPSDMIEA 898
Query: 930 NTPEGVPSAPSSLKIVNPTLDSLTLEWD--PPSHPNGILTEYTLKYQP 975
T + PS P + + + WD +T Y + Y+P
Sbjct: 899 FTKKAPPSQPPRIISSVRSGSRYIITWDHVVALSNESTVTGYKVLYRP 946
Score = 79.3 bits (194), Expect = 2e-14
Identities = 95/396 (23%), Positives = 160/396 (40%), Gaps = 40/396 (10%)
Query: 259 ERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKT 318
E+P + PE E L G V SL C A P P+ W +G + Y
Sbjct: 45 EQPINTIYPE------ESLEGKV-SLNCRARASPFPVYKWRMNNGDVDLTSDRYSMVGGN 97
Query: 319 LQIIHV-SEADSGNYQCIAKNALGAIHHTISVRV--KAAPYWITAPQNLVLSPGEDGTLI 375
L I + + D+G Y C+A N G + T + P+ + + G+ L+
Sbjct: 98 LVINNPDKQKDAGIYYCLASNNYGMVRSTEATLSFGYLDPFPPEERPEVRVKEGKGMVLL 157
Query: 376 CRANGNPKPRIS--WLTNGVPIEIAPDDPSRKIDGDT---IIFSNVQERSSAVYQCNASN 430
C + +S WL N P+ I D R+ T + +NV+ Y C S+
Sbjct: 158 CDPPYHFPDDLSYRWLLNEFPVFITMD--KRRFVSQTNGNLYIANVEASDKGNYSCFVSS 215
Query: 431 -EYGYLLANAFVNVLAEPPRILT--PANTLYQ-----VIANRPALLDCAFFGSPLPTIEW 482
+ + F+ ++ P R PA+ + Q + + L+C G+P+P I W
Sbjct: 216 PSITKSVFSKFIPLIPIPERTTKPYPADIVVQFKDVYALMGQNVTLECFALGNPVPDIRW 275
Query: 483 FKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKD-PTW 541
K + +I L+I Q + G Y C A N G K++ + ++ P W
Sbjct: 276 RKVLEPMPSTAEIST--SGAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQAFPEW 333
Query: 542 IVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVADVS 601
V+ V GS + + C T+ WLK+ + K L + DV+
Sbjct: 334 -VEHINDTEVDIGSDLYWPCVATGKPI--PTIRWLKNG--------YAYHKGELRLYDVT 382
Query: 602 DDDSGTYTCVANTTLDSVSASAVLSVVDVPNPPFDL 637
+++G Y C+A T ++ A+A L ++ + P F++
Sbjct: 383 FENAGMYQCIAENTYGAIYANAELKILALA-PTFEM 417
Score = 73.2 bits (178), Expect = 1e-12
Identities = 95/427 (22%), Positives = 164/427 (38%), Gaps = 73/427 (17%)
Query: 39 PPTITQQSPKDYIIDPRE-------NIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTM 91
P T+ P D ++ ++ N+ ++C A G P P W + ++ P
Sbjct: 233 PERTTKPYPADIVVQFKDVYALMGQNVTLECFALGNPVPDIRWRK-----VLEPMPSTAE 287
Query: 92 KPGTGTL--IINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPI 149
+G + I NI E EG+Y+C A N RG + + P W E +
Sbjct: 288 ISTSGAVLKIFNIQLED-----EGIYECEAENIRGKD-KHQARIYVQAFPEWV-EHINDT 340
Query: 150 TLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTRED 209
+ G L PC G P P I W+ N + R+ D+ F N
Sbjct: 341 EVDIGSDLYWPC-VATGKPIPTIRWLKNGYAYHKGELRLY-----DVTFENA------GM 388
Query: 210 YICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEG 269
Y C A + + +K++++ PTF E
Sbjct: 389 YQCIAENTYGAIYANAE---LKILAL-------------------------APTF---EM 417
Query: 270 NASNKEEL--RGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEA 327
N K+ L +G + +EC + P P W+K L + + + +L+I +++
Sbjct: 418 NPMKKKILAAKGGRVIIECKPKAAPKPKFSWSKGTEWLVNSSRILIWEDGSLEINNITRN 477
Query: 328 DSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRIS 387
D G Y C A+N G + T ++ + I AP N ++ GE+ T+ C A+ +P ++
Sbjct: 478 DGGIYTCFAENNRGKANSTGTLVITDPTRIILAPINADITVGENATMQCAASFDPALDLT 537
Query: 388 --WLTNGVPIEIAPDD----PSRKIDGD-TIIFSNVQERSSAVYQCNASNEYGYLLANAF 440
W NG I+ ++ + +D + ++ N Q + + Y C A A+A
Sbjct: 538 FVWSFNGYVIDFNKENIHYQRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNSSASAD 597
Query: 441 VNVLAEP 447
+ V P
Sbjct: 598 LVVRGPP 604
Score = 43.9 bits (102), Expect = 0.001
Identities = 29/99 (29%), Positives = 48/99 (48%), Gaps = 8/99 (8%)
Query: 36 LVQPPTITQQSPKDYIIDPREN-IVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPG 94
L PT K I+ + ++I+C+ K P P FSW++ GT + ++ ++ +
Sbjct: 409 LALAPTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFSWSK-GTEWLVNSSRILIWE-- 465
Query: 95 TGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVV 133
G+L IN ++ G+Y C A N RG A S +V
Sbjct: 466 DGSLEINNITRNDG----GIYTCFAENNRGKANSTGTLV 500
>gi|28373119 contactin 1 isoform 2 precursor [Homo sapiens]
Length = 1007
Score = 312 bits (800), Expect = 1e-84
Identities = 261/948 (27%), Positives = 412/948 (43%), Gaps = 92/948 (9%)
Query: 58 IVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQC 117
+ + C A+ P P + W N D+ D + G L+IN + K G+Y C
Sbjct: 50 VSLNCRARASPFPVYKWRMNNGDVDLTSDRYSMVG---GNLVINNPDKQKDA---GIYYC 103
Query: 118 TARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIF-WMD 176
A N G S + + E+ + ++ G+ +VL C PP P + + W+
Sbjct: 104 LASNNYGMVRSTEATLSFGYLDPFPPEERPEVRVKEGKGMVLLCDPPYHFPDDLSYRWLL 163
Query: 177 NSFQ---RLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARF-NHTQTIQQKQPISVKV 232
N F + + VSQ NG+LY +NV D + +Y C+ + T+++ K + +
Sbjct: 164 NEFPVFITMDKRRFVSQ-TNGNLYIANVEASD-KGNYSCFVSSPSITKSVFSK---FIPL 218
Query: 233 ISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLP 292
I + E ++++ P + + L G ++LEC A G P
Sbjct: 219 IPIPE-----------------RTTKPYPADIVV---QFKDVYALMGQNVTLECFALGNP 258
Query: 293 TPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVK 352
P I W K +P + + L+I ++ D G Y+C A+N G H + V+
Sbjct: 259 VPDIRWRKVLEPMPSTAEISTS-GAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQ 317
Query: 353 AAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTII 412
A P W+ + + G D C A G P P I WL NG G+ +
Sbjct: 318 AFPEWVEHINDTEVDIGSDLYWPCVATGKPIPTIRWLKNGYAYH----------KGELRL 367
Query: 413 FSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRI-LTPANTLYQVIANRPALLDCA 471
+ +V ++ +YQC A N YG + ANA + +LA P + P +++C
Sbjct: 368 Y-DVTFENAGMYQCIAENTYGAIYANAELKILALAPTFEMNPMKKKILAAKGGRVIIECK 426
Query: 472 FFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNE 531
+P P W KG + ++ ++ E+G+LEI ++ G YTC A N G A +
Sbjct: 427 PKAAPKPKFSWSKGTEW-LVNSSRILIWEDGSLEINNITRNDGGIYTCFAENNRGKANST 485
Query: 532 VHLEIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLW------LKDNRE-LPS 584
L I DPT I+ P A + G + +C D L LT +W + N+E +
Sbjct: 486 GTLVITDPTRIILAPINADITVGENATMQCAASFDPALDLTFVWSFNGYVIDFNKENIHY 545
Query: 585 DERFTVDKD-HLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVDVPNPPFDLELTDQL 643
F +D + L++ + +G YTC A T +D+ SASA L V P PP L + D
Sbjct: 546 QRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNSSASADLVVRGPPGPPGGLRIEDIR 605
Query: 644 DKSVQLSWTPGDDNNSPITKFII--------EYEDAMHKPGLWHHQTEVSGTQTTAQ-LK 694
SV L+W+ G DN+SPI+K+ I +++DA P + + G A+ +
Sbjct: 606 ATSVALTWSRGSDNHSPISKYTIQTKTILSDDWKDAKTDPPI------IEGNMEAARAVD 659
Query: 695 LSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPL 754
L P++ Y FRV+A N++G+ PS S + T + P+ P+ V G G L ITW PL
Sbjct: 660 LIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGGGRNRELTITWAPL 719
Query: 755 NGFESNGPGLQYKVSWRQKDGDDEWTSVVVAN--VSKYIVSGTPTFVP---YLIKVQALN 809
+ G Y V+++ DG +EW V V N +Y V T P + +KV+A N
Sbjct: 720 SREYHYGNNFGYIVAFKPFDG-EEWKKVTVTNPDTGRY-VHKDETMSPSTAFQVKVKAFN 777
Query: 810 DMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYY 869
+ G P V + +S +D P AP V V V++S+ VHW+ V K + + Y+I Y
Sbjct: 778 NKGDGPYSLVAVINSAQDAPSEAPTEVGVKVLSSSEISVHWEHVLEKIV----ESYQIRY 833
Query: 870 WKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVF 929
W + R + + L L P + Y + V N G GP S
Sbjct: 834 WAAHDKEEAANR------VQVTSQEYSARLENLLPDTQYFIEVGACNSAGCGPPSDMIEA 887
Query: 930 NTPEGVPSAPSSLKIVNPTLDSLTLEWD--PPSHPNGILTEYTLKYQP 975
T + PS P + + + WD +T Y + Y+P
Sbjct: 888 FTKKAPPSQPPRIISSVRSGSRYIITWDHVVALSNESTVTGYKVLYRP 935
Score = 79.3 bits (194), Expect = 2e-14
Identities = 95/396 (23%), Positives = 160/396 (40%), Gaps = 40/396 (10%)
Query: 259 ERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKT 318
E+P + PE E L G V SL C A P P+ W +G + Y
Sbjct: 34 EQPINTIYPE------ESLEGKV-SLNCRARASPFPVYKWRMNNGDVDLTSDRYSMVGGN 86
Query: 319 LQIIHV-SEADSGNYQCIAKNALGAIHHTISVRV--KAAPYWITAPQNLVLSPGEDGTLI 375
L I + + D+G Y C+A N G + T + P+ + + G+ L+
Sbjct: 87 LVINNPDKQKDAGIYYCLASNNYGMVRSTEATLSFGYLDPFPPEERPEVRVKEGKGMVLL 146
Query: 376 CRANGNPKPRIS--WLTNGVPIEIAPDDPSRKIDGDT---IIFSNVQERSSAVYQCNASN 430
C + +S WL N P+ I D R+ T + +NV+ Y C S+
Sbjct: 147 CDPPYHFPDDLSYRWLLNEFPVFITMD--KRRFVSQTNGNLYIANVEASDKGNYSCFVSS 204
Query: 431 -EYGYLLANAFVNVLAEPPRILT--PANTLYQ-----VIANRPALLDCAFFGSPLPTIEW 482
+ + F+ ++ P R PA+ + Q + + L+C G+P+P I W
Sbjct: 205 PSITKSVFSKFIPLIPIPERTTKPYPADIVVQFKDVYALMGQNVTLECFALGNPVPDIRW 264
Query: 483 FKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKD-PTW 541
K + +I L+I Q + G Y C A N G K++ + ++ P W
Sbjct: 265 RKVLEPMPSTAEIST--SGAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQAFPEW 322
Query: 542 IVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVADVS 601
V+ V GS + + C T+ WLK+ + K L + DV+
Sbjct: 323 -VEHINDTEVDIGSDLYWPCVATGKPI--PTIRWLKNG--------YAYHKGELRLYDVT 371
Query: 602 DDDSGTYTCVANTTLDSVSASAVLSVVDVPNPPFDL 637
+++G Y C+A T ++ A+A L ++ + P F++
Sbjct: 372 FENAGMYQCIAENTYGAIYANAELKILALA-PTFEM 406
Score = 73.2 bits (178), Expect = 1e-12
Identities = 95/427 (22%), Positives = 164/427 (38%), Gaps = 73/427 (17%)
Query: 39 PPTITQQSPKDYIIDPRE-------NIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTM 91
P T+ P D ++ ++ N+ ++C A G P P W + ++ P
Sbjct: 222 PERTTKPYPADIVVQFKDVYALMGQNVTLECFALGNPVPDIRWRK-----VLEPMPSTAE 276
Query: 92 KPGTGTL--IINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPI 149
+G + I NI E EG+Y+C A N RG + + P W E +
Sbjct: 277 ISTSGAVLKIFNIQLED-----EGIYECEAENIRGKD-KHQARIYVQAFPEWV-EHINDT 329
Query: 150 TLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTRED 209
+ G L PC G P P I W+ N + R+ D+ F N
Sbjct: 330 EVDIGSDLYWPC-VATGKPIPTIRWLKNGYAYHKGELRLY-----DVTFENA------GM 377
Query: 210 YICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEG 269
Y C A + + +K++++ PTF E
Sbjct: 378 YQCIAENTYGAIYANAE---LKILAL-------------------------APTF---EM 406
Query: 270 NASNKEEL--RGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEA 327
N K+ L +G + +EC + P P W+K L + + + +L+I +++
Sbjct: 407 NPMKKKILAAKGGRVIIECKPKAAPKPKFSWSKGTEWLVNSSRILIWEDGSLEINNITRN 466
Query: 328 DSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRIS 387
D G Y C A+N G + T ++ + I AP N ++ GE+ T+ C A+ +P ++
Sbjct: 467 DGGIYTCFAENNRGKANSTGTLVITDPTRIILAPINADITVGENATMQCAASFDPALDLT 526
Query: 388 --WLTNGVPIEIAPDD----PSRKIDGD-TIIFSNVQERSSAVYQCNASNEYGYLLANAF 440
W NG I+ ++ + +D + ++ N Q + + Y C A A+A
Sbjct: 527 FVWSFNGYVIDFNKENIHYQRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNSSASAD 586
Query: 441 VNVLAEP 447
+ V P
Sbjct: 587 LVVRGPP 593
Score = 43.9 bits (102), Expect = 0.001
Identities = 29/99 (29%), Positives = 48/99 (48%), Gaps = 8/99 (8%)
Query: 36 LVQPPTITQQSPKDYIIDPREN-IVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPG 94
L PT K I+ + ++I+C+ K P P FSW++ GT + ++ ++ +
Sbjct: 398 LALAPTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFSWSK-GTEWLVNSSRILIWE-- 454
Query: 95 TGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVV 133
G+L IN ++ G+Y C A N RG A S +V
Sbjct: 455 DGSLEINNITRNDG----GIYTCFAENNRGKANSTGTLV 489
>gi|28373126 contactin 4 isoform c precursor [Homo sapiens]
Length = 698
Score = 269 bits (688), Expect = 1e-71
Identities = 208/692 (30%), Positives = 310/692 (44%), Gaps = 61/692 (8%)
Query: 376 CRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYL 435
C+ANG PKP WL NG P+ + D +I+ T+ + V + +YQC A N++G +
Sbjct: 9 CKANGRPKPTYKWLKNGEPL-LTRD--RIQIEQGTLNITIVNLSDAGMYQCLAENKHGVI 65
Query: 436 LANAFVNVLAEPP---RILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALH 492
+NA ++V+A P R L TL +V +++C SP P W KG +
Sbjct: 66 FSNAELSVIAVGPDFSRTLLKRVTLVKV--GGEVVIECKPKASPKPVYTWKKGRDILKEN 123
Query: 493 EDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQ 552
E I + E+G L I K G+YTC+A N G A + +L +KDPT ++ P V
Sbjct: 124 ERI-TISEDGNLRIINVTKSDAGSYTCIATNHFGTASSTGNLVVKDPTRVMVPPSSMDVT 182
Query: 553 RGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH------------LVVADV 600
G + C+V HDH+L + W + + D D DH L++ ++
Sbjct: 183 VGESIVLPCQVTHDHSLDIVFTWSFNGHLIDFDR----DGDHFERVGGQDSAGDLMIRNI 238
Query: 601 SDDDSGTYTCVANTTLDSVSASAVLSVVDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSP 660
+G Y C+ T++D +SA+A L V P PP + + + D + QLSW PG DN+SP
Sbjct: 239 QLKHAGKYVCMVQTSVDRLSAAADLIVRGPPGPPEAVTIDEITDTTAQLSWRPGPDNHSP 298
Query: 661 ITKFIIEYEDAMHKPGLWHHQTEV-----SGTQTTAQLKLSPYVNYSFRVMAVNSIGKSL 715
IT ++I+ W + V T T + L+P+V Y FR +A N IG
Sbjct: 299 ITMYVIQARTPFSVG--WQAVSTVPELIDGKTFTATVVGLNPWVEYEFRTVAANVIGIGE 356
Query: 716 PSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVSWRQKDG 775
PS SE+ T+ + P+ P V G G LVITW+ + NG G Y V++R G
Sbjct: 357 PSRPSEKRRTEEALPEVTPANVSGGGGSKSELVITWETVPEELQNGRGFGYVVAFRPY-G 415
Query: 776 DDEW--TSVVVANVSKYIV--SGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMV 831
W T + A+ S+Y+ F P+ +KV N+ G P + +S E+ P
Sbjct: 416 KMIWMLTVLASADASRYVFRNESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTK 475
Query: 832 APGNVRVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQ 891
P ++ +++T EV W PL+ RG +QGY + YW+ + + R KI T
Sbjct: 476 PPASIFARSLSATDIEVFW-ASPLEKNRGRIQGYEVKYWRHEDKEENAR-----KIRTV- 528
Query: 892 GSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDS 951
G++T + L+ Y L V+ N G GP+S T + PS P I N +
Sbjct: 529 GNQTSTKITNLKGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSK 588
Query: 952 LTLEWDP------PSHPNGILTEYTLKYQPINSTHELGPLVDLKIPANKTRWTLKNLNFS 1005
+ L WD S G Y Q S I NKT L +L F
Sbjct: 589 IILNWDQVKALDNESEVKGYKVLYRWNRQSSTSV----------IETNKTSVEL-SLPFD 637
Query: 1006 TRYKFYFYAQTSAGSGSQITEEAVTTVDEAMA 1037
Y + G GS + + + A A
Sbjct: 638 EDYIIEIKPFSDGGDGSSSEQIRIPKISNAYA 669
Score = 115 bits (289), Expect = 2e-25
Identities = 150/607 (24%), Positives = 240/607 (39%), Gaps = 90/607 (14%)
Query: 469 DCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMA 528
+C G P PT +W K + + I + E GTL I + G Y C+A NK G+
Sbjct: 8 ECKANGRPKPTYKWLKNGEPLLTRDRIQI--EQGTLNITIVNLSDAGMYQCLAENKHGVI 65
Query: 529 KNEVHLEIKDPTWIVKQPEYA--------VVQRGSMVSFECKVKHDHTLSLTVLWLKDNR 580
+ L + I P+++ +V+ G V ECK K T W K
Sbjct: 66 FSNAELSV-----IAVGPDFSRTLLKRVTLVKVGGEVVIECKPKASPKPVYT--WKKGRD 118
Query: 581 ELPSDERFTVDKD-HLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVD---VPNPPFD 636
L +ER T+ +D +L + +V+ D+G+YTC+A + S++ L V D V PP
Sbjct: 119 ILKENERITISEDGNLRIINVTKSDAGSYTCIATNHFGTASSTGNLVVKDPTRVMVPPSS 178
Query: 637 LELTDQLDKSVQLSWTPGDDNNSPI------TKFIIEYEDAMHKPGLWHHQTEVSGTQTT 690
+++T + +S+ L D++ I +I+++ + G H V G +
Sbjct: 179 MDVT--VGESIVLPCQVTHDHSLDIVFTWSFNGHLIDFD----RDG--DHFERVGGQDSA 230
Query: 691 AQLKLSPYVNYSFRVMAVNSIGKSL-PSEASEQYLTKASE-----PDKNPTAVEGLGSEP 744
L + R + + GK + + S L+ A++ P P AV
Sbjct: 231 GDLMI--------RNIQLKHAGKYVCMVQTSVDRLSAAADLIVRGPPGPPEAVTIDEITD 282
Query: 745 DNLVITWKPLNGFESNGPGLQY--------KVSWRQKDGDDEWTSVVVANVSKYIVSGTP 796
++W+P G +++ P Y V W+ E ++ V G
Sbjct: 283 TTAQLSWRP--GPDNHSPITMYVIQARTPFSVGWQAVSTVPE---LIDGKTFTATVVGLN 337
Query: 797 TFVPYLIKVQALNDMGFA-PEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPVPL 855
+V Y + A N +G P + E LP V P NV + + + W+ VP
Sbjct: 338 PWVEYEFRTVAANVIGIGEPSRPSEKRRTEEALPEVTPANVSGGGGSKSELVITWETVPE 397
Query: 856 KSIRGHLQGY--------RIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSH 907
+ G GY ++ + T +S R++ F+ H PFS
Sbjct: 398 ELQNGRGFGYVVAFRPYGKMIWMLTVLASADASRYV------FRNESVH-------PFSP 444
Query: 908 YTLNVRVVNGKGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLE--WDPPSHPN-G 964
+ + V V N KGEGP SP V + E P+ P + I +L + +E W P N G
Sbjct: 445 FEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPA-SIFARSLSATDIEVFWASPLEKNRG 503
Query: 965 ILTEYTLKYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQI 1024
+ Y +KY E ++ N+T + NL S Y A SAG+G
Sbjct: 504 RIQGYEVKYWRHEDKEENAR--KIRTVGNQTSTKITNLKGSVLYHLAVKAYNSAGTGPSS 561
Query: 1025 TEEAVTT 1031
VTT
Sbjct: 562 ATVNVTT 568
Score = 71.6 bits (174), Expect = 4e-12
Identities = 55/180 (30%), Positives = 89/180 (49%), Gaps = 19/180 (10%)
Query: 56 ENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVT---MKPGTGTLIINIMSEGKAETYE 112
EN+ +C+A G+P P++ W +NG +PL+T ++ GTL I I++ A
Sbjct: 3 ENVFWECKANGRPKPTYKWLKNG-------EPLLTRDRIQIEQGTLNITIVNLSDA---- 51
Query: 113 GVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITL-QSGQSLVLPCRPPIGLPPPI 171
G+YQC A N+ G SN + + P +++ L+ +TL + G +V+ C+P P P+
Sbjct: 52 GMYQCLAENKHGVIFSNAELSVIAVGPDFSRTLLKRVTLVKVGGEVVIECKPKAS-PKPV 110
Query: 172 IFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVK 231
W L ++ER++ +G+L NV D Y C A NH T + VK
Sbjct: 111 YTWKKGR-DILKENERITISEDGNLRIINVTKSDA-GSYTCIAT-NHFGTASSTGNLVVK 167
Score = 63.5 bits (153), Expect = 1e-09
Identities = 46/176 (26%), Positives = 81/176 (46%), Gaps = 7/176 (3%)
Query: 279 GNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKN 338
G + +EC + P P+ W K +L +N + + + L+II+V+++D+G+Y CIA N
Sbjct: 94 GGEVVIECKPKASPKPVYTWKKGRDILKENERITISEDGNLRIINVTKSDAGSYTCIATN 153
Query: 339 ALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRI--SWLTNGVPIE 396
G T ++ VK + P ++ ++ GE L C+ + I +W NG I+
Sbjct: 154 HFGTASSTGNLVVKDPTRVMVPPSSMDVTVGESIVLPCQVTHDHSLDIVFTWSFNGHLID 213
Query: 397 IAPD-DPSRKIDGD----TIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEP 447
D D ++ G ++ N+Q + + Y C L A A + V P
Sbjct: 214 FDRDGDHFERVGGQDSAGDLMIRNIQLKHAGKYVCMVQTSVDRLSAAADLIVRGPP 269
Score = 59.3 bits (142), Expect = 2e-08
Identities = 53/196 (27%), Positives = 89/196 (45%), Gaps = 22/196 (11%)
Query: 285 ECIAEGLPTPIIYWAKE-DGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGAI 343
EC A G P P W K + +L ++R + + TL I V+ +D+G YQC+A+N G I
Sbjct: 8 ECKANGRPKPTYKWLKNGEPLLTRDRIQIE--QGTLNITIVNLSDAGMYQCLAENKHGVI 65
Query: 344 --HHTISVRVKAAPYWITAPQNLVL-SPGEDGTLICRANGNPKPRISW------LTNGVP 394
+ +SV + T + + L G + + C+ +PKP +W L
Sbjct: 66 FSNAELSVIAVGPDFSRTLLKRVTLVKVGGEVVIECKPKASPKPVYTWKKGRDILKENER 125
Query: 395 IEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTPA 454
I I+ D R I NV + + Y C A+N +G + + V+ +P R++ P
Sbjct: 126 ITISEDGNLRII--------NVTKSDAGSYTCIATNHFGTASSTGNL-VVKDPTRVMVPP 176
Query: 455 NTLYQVIANRPALLDC 470
+++ V +L C
Sbjct: 177 SSM-DVTVGESIVLPC 191
>gi|222352127 sidekick 2 [Homo sapiens]
Length = 2172
Score = 264 bits (674), Expect = 4e-70
Identities = 244/994 (24%), Positives = 417/994 (41%), Gaps = 71/994 (7%)
Query: 58 IVIQCEAKGKPPPSFSWTRNG---THFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGV 114
+V+ C A+G P F W N T F ++ ++T T+ G
Sbjct: 44 LVLTCMAEGSWPLEFKWLHNNRELTKFSLEYRYMITSLD---------------RTHAGF 88
Query: 115 YQCTARNERGAAVSNNIVVRPSRSPLWTK-EKLEPITLQSGQSLVLPCRPPIGLPPPIIF 173
Y+C RN GA + V+ + + + EK + ++ G++ V+ P P +
Sbjct: 89 YRCIVRNRMGALLQRQTEVQVAYMGSFEEGEKHQSVS--HGEAAVIRAPRIASFPQPQVT 146
Query: 174 WMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVI 233
W + +++P S R++ L L + + D Y+ + + QPI++ V
Sbjct: 147 WFRDG-RKIPPSSRIAITLENTLVILSTVAPDAGRYYVQAVNDKNGDN-KTSQPITLTVE 204
Query: 234 SVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPT 293
+V D IA PT + P N S + ++LEC+A P
Sbjct: 205 NVGGPADPIA------------------PTIIIPPKNTSVVAGT--SEVTLECVANARPL 244
Query: 294 PIIY--WAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIA---KNALGAIHHTIS 348
++ W K+DG+L N + L I + + +D+G Y+C A +++ ++
Sbjct: 245 IKLHIIW-KKDGVLLSGGISDHN--RRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAY 301
Query: 349 VRVKAAPYWITAPQNLVLSPGEDGTLI-CRANGNPKPRISWLTNGVPIEIAPDDPSRKID 407
+ V P ++ P+ + + E I C+A G P P I+W + +E+ R+ +
Sbjct: 302 LSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRN 361
Query: 408 GDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIANRPAL 467
+ S + + ++QC A N G + + ++ V + P I T VI +
Sbjct: 362 DGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNI-TRGPLDSTVIDGMSVV 420
Query: 468 LDCAFFGSPLPTIEWFKGAK---GSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNK 524
L C G+P P I W KG + ++ + E+G+L I GTYTC+A N
Sbjct: 421 LACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNS 480
Query: 525 LGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPS 584
G+ + L + T I K P+ V +G+ S C V HD +++ +W KD L +
Sbjct: 481 RGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGT 540
Query: 585 DE--RFTVDKD-HLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVDVPNPPFD--LEL 639
+ R +D++ L ++ D GTYTC + + S SA L V +P+ P L
Sbjct: 541 ESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATL 600
Query: 640 TDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYV 699
+ +++ L+WT D NSP+ ++I+E + + + T T + L P
Sbjct: 601 STVERRAINLTWTKPFDGNSPLIRYILEMSENNAPWTVLLASVDPKATSVTVK-GLVPAR 659
Query: 700 NYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFES 759
+Y FR+ AVN +GK S+ +E+ P P V G +++I W+P
Sbjct: 660 SYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQ 719
Query: 760 NG--PGLQYKVSWRQKDGDDEWTSVVVANVSKYIVSGTPTFVPYLIKVQALNDMGFAPEP 817
NG G + ++ ++ A+V+ ++ + Y I+V A N G
Sbjct: 720 NGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYS 779
Query: 818 AVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSK 877
+ V + + +P V PGNV NST W+ + I G QGY++ W+ + +
Sbjct: 780 SKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEE 839
Query: 878 RNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPS 937
FQ S G + GL+ F+ Y +V G+GP S ++ T E VP
Sbjct: 840 VTMVTARPN---FQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPG 896
Query: 938 APSSLKIVNPTLDSLTLEWDPPSHPNGILTEYTLKYQPINSTHELGPLVDLKIPANKTRW 997
L SL + W P NGILT Y + ++ N T+ V +P +
Sbjct: 897 PVGHLSFSEILDTSLKVSWQEPGEKNGILTGYRISWEEYNRTN---TRVTHYLPNVTLEY 953
Query: 998 TLKNLNFSTRYKFYFYAQTSAGSGSQITEEAVTT 1031
+ L T Y A TS G G Q++ +++
Sbjct: 954 RVTGLTALTTYTIEVAAMTSKGQG-QVSASTISS 986
Score = 173 bits (438), Expect = 1e-42
Identities = 121/416 (29%), Positives = 192/416 (46%), Gaps = 36/416 (8%)
Query: 629 DVPNPPFD--LELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWH-HQTEVS 685
D P PP ++ D +SV LSW PG D SP+ + I+ + G W H VS
Sbjct: 1398 DRPQPPSRPMVQQEDVRARSVLLSWEPGSDGLSPVRYYTIQTREL--PSGRWALHSASVS 1455
Query: 686 GTQTTAQL-KLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEP 744
++ + +L P+ +Y FRV A N IG S SE SE T + PD+ PT +
Sbjct: 1456 HNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTT 1515
Query: 745 DNLVITWKPLNGFESNGPGLQYKVSWRQ--------------KDGDDEWTSVV----VAN 786
+++I W+P + NG L +++ +R+ + W + + N
Sbjct: 1516 TSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRN 1575
Query: 787 VSK-----YIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVV 841
+S+ Y + Y I++ N +G P GE +P AP NV V+
Sbjct: 1576 LSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGA 1635
Query: 842 NSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPG 901
+T +V W+P PL S G +QGY+IY+W+ Q R ++ +++ T ++ L
Sbjct: 1636 TATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQ------RGNLTERVKTLFLAENSVKLKN 1689
Query: 902 LEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDPPSH 961
L ++ Y ++V N G+GP S T + PSAPSS+K T S+ + W+ P
Sbjct: 1690 LTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQF 1749
Query: 962 PNGILTEYTLKYQPINSTHELGPLVDLKIPANKTRW-TLKNLNFSTRYKFYFYAQT 1016
PNGIL Y L Y+P + + +V + + N W +K+L Y+F A+T
Sbjct: 1750 PNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKT 1805
Score = 155 bits (392), Expect = 2e-37
Identities = 119/424 (28%), Positives = 194/424 (45%), Gaps = 19/424 (4%)
Query: 619 VSASAVLSVV--DVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPG 676
VSAS + S V ++P PP +L +++ +SV L + PG D + I+++++E + + G
Sbjct: 979 VSASTISSGVPPELPGPPTNLGISNIGPRSVTLQFRPGYDGKTSISRWLVEAQVGVVGEG 1038
Query: 677 ----LWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDK 732
L H + ++ L+P+ YSFR+ VN +G S PS+ S + T + PD
Sbjct: 1039 EEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDM 1098
Query: 733 NPTAVEGLGSEPDNLVITWKPLNGFESNG--PGLQYKVSWRQKDGDDEWTSVVVANVSK- 789
P V + +L + W PL E NG + YK+ + + DG + S VV + +
Sbjct: 1099 APANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVER 1158
Query: 790 -YIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEV 848
Y + + Y ++VQA N +G P V+G + E +P P NV S+ V
Sbjct: 1159 DYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLV 1218
Query: 849 HWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHY 908
W VP G + GY++ Y + S ++ +E S L GL + Y
Sbjct: 1219 RWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVE------GNSSRSAQLTGLGKYVLY 1272
Query: 909 TLNVRVVNGKGEG-PASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDPPSHPNGILT 967
+ V G+G P+ P + T + VP P + S+ L W PP+ PNGI+
Sbjct: 1273 EVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIIL 1332
Query: 968 EYTLKYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEE 1027
Y + ++ +N+T V++ P+ + ++T L + Y F AQT G G
Sbjct: 1333 AYQITHR-LNTTTANTATVEVLAPSAR-QYTATGLKPESVYLFRITAQTRKGWGEAAEAL 1390
Query: 1028 AVTT 1031
VTT
Sbjct: 1391 VVTT 1394
Score = 79.3 bits (194), Expect = 2e-14
Identities = 101/484 (20%), Positives = 177/484 (36%), Gaps = 62/484 (12%)
Query: 634 PFDLELTDQLDKSVQLSWTPG--DDNNSPITKFIIEYEDAMHK------------PGL-W 678
P L +T SV + W P D N + F I Y + +++ PG W
Sbjct: 1505 PTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATW 1564
Query: 679 HHQTEVSGTQTTAQLKLSPYV--------NYSFRVMAVNSIGKSLPSEASEQYLTKASEP 730
T + + ++ L+ Y Y R+ N++G+ PS ++ + P
Sbjct: 1565 AELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEG-PSSPPQEVFVGEAVP 1623
Query: 731 DKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVS-WRQKDGD-DEWTSVVVANVS 788
P V G+ L +TW+P NG YK+ W + G+ E + +
Sbjct: 1624 TAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAEN 1683
Query: 789 KYIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEV 848
+ + Y++ V A N G P G + + P AP +V+ + + +T V
Sbjct: 1684 SVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPS-APSSVKFSELTTTSVNV 1742
Query: 849 HWDPVPLKSIRGHLQGYRIYYW---------KTQSSSKRNRRHIEKKILTFQGSKTHGML 899
W+ + G L+GYR+ Y K + + + K+ T+
Sbjct: 1743 SWEAPQFPN--GILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFR 1800
Query: 900 PGLEPFSHYT-LNVRVVNGKGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDP 958
+ F++ + V G GEG P GVP I+ ++ + W
Sbjct: 1801 IRAKTFTYGPEIEANVTTGPGEGAPGPP-------GVP-------IIVRYSSAIAIHWSS 1846
Query: 959 PSHPNGILTEYTLKYQPINSTHELGPLVDLKIPANKTRWTLKN--LNFSTRYKFYFYAQT 1016
G +T Y ++ +P S L ++ IP + +T L Y F A
Sbjct: 1847 GDPGKGPITRYVIEARP--SDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVN 1904
Query: 1017 SAGSGSQITEEAVTTVDEAMASRQVDIATQGWFIGLMCAVALLILILLIVCFIRRNKGGK 1076
G G+ + +A + + WF+ ++ V L+ ++LL+ I R + K
Sbjct: 1905 DYGFGTPSSPSQSVPAQKANPFYE-----EWWFLVVIALVGLIFILLLVFVLIIRGQSKK 1959
Query: 1077 YPVK 1080
Y K
Sbjct: 1960 YAKK 1963
Score = 77.8 bits (190), Expect = 6e-14
Identities = 99/380 (26%), Positives = 148/380 (38%), Gaps = 39/380 (10%)
Query: 277 LRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYK-NFEKTLQIIHVSEADSGNYQCI 335
L GN L L C+AEG W E L NR + K + E I + +G Y+CI
Sbjct: 39 LEGNRLVLTCMAEG------SWPLEFKWLHNNRELTKFSLEYRYMITSLDRTHAGFYRCI 92
Query: 336 AKNALGA-IHHTISVRVKAAPYWITAPQNLVLSPGEDGTLIC-RANGNPKPRISWLTNGV 393
+N +GA + V+V + ++ +S GE + R P+P+++W +G
Sbjct: 93 VRNRMGALLQRQTEVQVAYMGSFEEGEKHQSVSHGEAAVIRAPRIASFPQPQVTWFRDGR 152
Query: 394 PIEIAPDDPSRKI----DGDTIIFSNVQERS-----SAVYQCNASNEYGYLLANAFVNV- 443
I PS +I + +I S V + AV N N+ + NV
Sbjct: 153 KI-----PPSSRIAITLENTLVILSTVAPDAGRYYVQAVNDKNGDNKTSQPITLTVENVG 207
Query: 444 -LAEP--PRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHE 500
A+P P I+ P V L+C PL + G L I
Sbjct: 208 GPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGVLLSGGI--SDH 265
Query: 501 NGTLEIPVAQKDSTGTYTCVARNKLGMAKNEV---HLEIKDPTWIVKQPE-YAVVQRGSM 556
N L IP G Y C A + + V +L + +P VK+PE + + +
Sbjct: 266 NRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKV 325
Query: 557 VSFECKVKHDHTLSLTVLWLKDNR--ELPSDERFTVDKD-HLVVADVSDDDSGTYTCVAN 613
V C+ K S+T W KD E+ RF D L ++ + DD+G + C A
Sbjct: 326 VDIPCQAKGVPPPSIT--WYKDAAVVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFAR 383
Query: 614 TTLDSVSASAVLSVVDV-PN 632
V S L+V + PN
Sbjct: 384 NAAGEVQTSTYLAVTSIAPN 403
Score = 63.2 bits (152), Expect = 1e-09
Identities = 42/142 (29%), Positives = 71/142 (50%), Gaps = 9/142 (6%)
Query: 34 LDLVQPPTITQQSPKDYIIDPRENIV-IQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMK 92
L +++PP ++ P+ +I E +V I C+AKG PPPS +W ++ +++K +
Sbjct: 302 LSVLEPPQFVKE-PERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQR 360
Query: 93 PGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQ 152
G I ++ + G++QC ARN G ++ + S +P T+ L+ T+
Sbjct: 361 NDGGLQISGLVPDD-----TGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDS-TVI 414
Query: 153 SGQSLVLPCRPPIGLPPPIIFW 174
G S+VL C G P P I W
Sbjct: 415 DGMSVVLACETS-GAPRPAITW 435
Score = 56.2 bits (134), Expect = 2e-07
Identities = 90/411 (21%), Positives = 153/411 (37%), Gaps = 56/411 (13%)
Query: 647 VQLSWTPGDDNNSPITKFIIEYE--DAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFR 704
V+ S P D N + + + Y+ D+ +P W E + +++ L YV Y +
Sbjct: 1218 VRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFW--LVEGNSSRSAQLTGLGKYVLYEVQ 1275
Query: 705 VMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGL 764
V+A IG PS T P P + ++ + W+P NG L
Sbjct: 1276 VLAFTRIGDGSPSHPPILERTLDDVPGP-PMGILFPEVRTTSVRLIWQPPAA--PNGIIL 1332
Query: 765 QYKVSWRQKD--GDDEWTSVVVANVSKYIVSGTPTFVPYLIKVQALNDMGF--APEPAVV 820
Y+++ R + V+ + +Y +G YL ++ A G+ A E VV
Sbjct: 1333 AYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVV 1392
Query: 821 MGHSGE-----DLPMVAPGNVRVNVVNSTLAEVHWDPVP--LKSIRGHLQGYRIYYWKTQ 873
+ PMV +VR V + W+P L +R YY
Sbjct: 1393 TTEKRDRPQPPSRPMVQQEDVRARSVL-----LSWEPGSDGLSPVR--------YYTIQT 1439
Query: 874 SSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASPD-RVFNTP 932
R + ++ S ++ L+PF+ Y V+ N G+ S + T
Sbjct: 1440 RELPSGRWALHSASVSHNASSF--IVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTL 1497
Query: 933 EGVPS-APSSLKIVNPTLDSLTLEWDPPSHP--NGILTEYTLKYQ--------------- 974
+ P AP+ L + T S+ + W PP+ NGIL + ++Y+
Sbjct: 1498 QAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGI 1557
Query: 975 --PINSTHELGPLVDLKIPANK--TRWTLKNLNFSTRYKFYFYAQTSAGSG 1021
P + EL + ++ + T++ L NLN RY+ + G G
Sbjct: 1558 NNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEG 1608
Score = 49.3 bits (116), Expect = 2e-05
Identities = 32/105 (30%), Positives = 50/105 (47%), Gaps = 9/105 (8%)
Query: 631 PNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHH-----QTEVS 685
P PP + + + ++ + W+ GD PIT+++IE + GLW EVS
Sbjct: 1825 PGPP-GVPIIVRYSSAIAIHWSSGDPGKGPITRYVIEARPS--DEGLWDILIKDIPKEVS 1881
Query: 686 GTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEP 730
+ + L P V+Y FRV+AVN G PS S+ + + P
Sbjct: 1882 SYTFSMDI-LKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQKANP 1925
Score = 35.4 bits (80), Expect = 0.32
Identities = 37/167 (22%), Positives = 65/167 (38%), Gaps = 6/167 (3%)
Query: 40 PTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKP-GTGTL 98
P IT+ P D + ++V+ CE G P P+ +W + L P +G+L
Sbjct: 402 PNITR-GPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSL 460
Query: 99 IINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLV 158
+I+ A G Y C A N RG ++ +V +R+ + + + + + S+V
Sbjct: 461 LISPTHISDA----GTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMV 516
Query: 159 LPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPED 205
+ I+ D + R+ NG L+ S D
Sbjct: 517 CGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGD 563
>gi|119220552 sidekick 1 [Homo sapiens]
Length = 2213
Score = 261 bits (668), Expect = 2e-69
Identities = 253/990 (25%), Positives = 412/990 (41%), Gaps = 83/990 (8%)
Query: 58 IVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQC 117
+V+ C A+G P F W R+ D +T II + + A G Y+C
Sbjct: 122 LVLTCLAEGSWPLEFKWMRD--------DSELTTYSSEYKYIIPSLQKLDA----GFYRC 169
Query: 118 TARNERGAAVS--NNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWM 175
RN GA + + + V S + T ++ T+ G++ +L P P P + W
Sbjct: 170 VVRNRMGALLQRKSEVQVAYMGSFMDTDQRK---TVSQGRAAILNLLPITSYPRPQVTWF 226
Query: 176 DNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVISV 235
+ +P S R++ L L D Y+ Q + +K
Sbjct: 227 REGHKIIP-SNRIAITLENQLVILATTTSDAGAYYV--------QAVNEKN--------- 268
Query: 236 DELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTP- 294
E + +LS G + PT + P GN S + +LECIA P
Sbjct: 269 GENKTSPFIHLSIARDVGTPETMA--PTIVVPPGNRS--VVAGSSETTLECIASARPVED 324
Query: 295 -IIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAK---NALGAIHHTISVR 350
+ W K +G+ + + +F + L I + + AD+G Y C A +A T +
Sbjct: 325 LSVTW-KRNGV--RITSGLHSFGRRLTISNPTSADTGPYVCEAALPGSAFEPARATAFLF 381
Query: 351 VKAAPYWITAPQNLVLSPGEDGTLI-CRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGD 409
+ PY+ P++ + + E+ I C+A G P P + W + + I + + +
Sbjct: 382 IIEPPYFTAEPESRISAEVEETVDIGCQAMGVPLPTLQWYKDAISISRLQNPRYKVLASG 441
Query: 410 TIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIANRPALLD 469
+ ++ S ++QC ASNE G + + +++V P + T V A+L
Sbjct: 442 GLRIQKLRPEDSGIFQCFASNEGGEIQTHTYLDVTNIAP-VFTQRPVDTTVTDGMTAILR 500
Query: 470 CAFFGSPLPTIEWFKG----AKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKL 525
C G+P P I W + A GS + ++L E+G L+I G YTC A N
Sbjct: 501 CEVSGAPKPAITWKRENHILASGS-VRIPRFMLLESGGLQIAPVFIQDAGNYTCYAANTE 559
Query: 526 GMAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNREL--P 583
G L + + T IV PE VV +G+ + C HD +SL +W KDN L
Sbjct: 560 GSLNASATLTVWNRTSIVHPPEDHVVIKGTTATLHCGATHDPRVSLRYVWKKDNVALTPS 619
Query: 584 SDERFTVDKD-HLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVDVPNPPFDLELTDQ 642
S R V+KD L+++ D G Y+C + + S A L V+++P+ P +L ++
Sbjct: 620 STSRIVVEKDGSLLISQTWSGDIGDYSCEIVSEGGNDSRMARLEVIELPHSPQNLLVSPN 679
Query: 643 LDKS--VQLSWTPGDDNNSPITKFIIEYED--AMHKPGLWHHQTEVSGTQTTAQLKLSPY 698
S V LSW D NSPI +I+E + + K L + E++G + L+P
Sbjct: 680 SSHSHAVVLSWVRPFDGNSPILYYIVELSENNSPWKVHLSNVGPEMTGVTVSG---LTPA 736
Query: 699 VNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFE 758
Y FRV AVN +G+ S + + + P P + G ++++ W+P E
Sbjct: 737 RTYQFRVCAVNEVGRGQYSAETSRLMLPEEPPSAPPKNIVASGRTNQSIMVQWQPPPETE 796
Query: 759 SNGPGLQYKVSWRQK--DGDDEWTSVVVANVSKYIVSGTPTFVPYLIKVQALNDMGFAPE 816
NG Y + +R G+ + ++ V+ +V+ + Y I+V A N G
Sbjct: 797 HNGVLRGYILRYRLAGLPGEYQQRNITSPEVNYCLVTDLIIWTQYEIQVAAYNGAGLGVF 856
Query: 817 PAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSS 876
V ++ + +P P NV+ VNST + W+P P + I G QGY++ W +
Sbjct: 857 SRAVTEYTLQGVPTAPPQNVQTEAVNSTTIQFLWNPPPQQFINGINQGYKLLAWPADAPE 916
Query: 877 KRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVP 936
I F G HG + L+ F+ Y +V G+GP S ++ T E P
Sbjct: 917 AVTVVTIAP---DFHGVH-HGHITNLKKFTAYFTSVLCFTTPGDGPPSTPQLVWTQEDKP 972
Query: 937 SAPSSLKIVNPTLDSLTLEWDPPSHPNGILTEYTLKYQPINS-----THELGPLVDLKIP 991
A L SL + W P NGI+T Y + ++ TH L
Sbjct: 973 GAVGHLSFTEILDTSLKVSWQEPLEKNGIITGYQISWEVYGRNDSRLTHTLN-------- 1024
Query: 992 ANKTRWTLKNLNFSTRYKFYFYAQTSAGSG 1021
+ + ++ L+ T Y A T+ G+G
Sbjct: 1025 STTHEYKIQGLSSLTTYTIDVAAVTAVGTG 1054
Score = 152 bits (384), Expect = 2e-36
Identities = 115/416 (27%), Positives = 188/416 (45%), Gaps = 39/416 (9%)
Query: 631 PNPPFDLELTDQLD---KSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQTEVSGT 687
P PP +L L Q + +S++L W PG D SPI F ++ + G W +
Sbjct: 1477 PAPPREL-LVPQAEVTARSLRLQWVPGSDGASPIRYFTMQVRELPR--GEWQTYSSSISH 1533
Query: 688 QTTAQL--KLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPD 745
+ TA + +L P+ +Y R+ A N IG S S +E T P + P +V
Sbjct: 1534 EATACVVDRLRPFTSYKLRLKATNDIGDSDFSSETEAVTTLQDVPGEPPGSVSATPHTTS 1593
Query: 746 NLVITWKPLNGFESNGPGLQYKVSWRQKD-----GDDEWT--------SVVVANVSKYIV 792
+++I W+P NG Y++ +R+ + G + T + + A S V
Sbjct: 1594 SVLIQWQPPRDESLNGLLQGYRIYYRELEYEAGSGTEAKTLKNPIALHAELTAQSSFKTV 1653
Query: 793 SGTPT-----------FVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVV 841
+ + T + Y + + A N +G +P A V GE P +AP NV+V +
Sbjct: 1654 NSSSTSTMCELTHLKKYRRYEVIMTAYNIIGESPASAPVEVFVGEAAPAMAPQNVQVTPL 1713
Query: 842 NSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPG 901
++ EV WDP P +S G++QGY+IYYW+ S ++ + K+L L
Sbjct: 1714 TASQLEVTWDPPPPESQNGNIQGYKIYYWEADSQNETEK----MKVLFLPEPVVR--LKN 1767
Query: 902 LEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDPPSH 961
L + Y +++ N G+GP S + T + P APS L T +L + W P+
Sbjct: 1768 LTSHTKYLVSISAFNAAGDGPKSDPQQGRTHQAAPGAPSFLAFSEITSTTLNVSWGEPAA 1827
Query: 962 PNGILTEYTLKYQPINSTHELGPLVDLKIPANKTRW-TLKNLNFSTRYKFYFYAQT 1016
NGIL Y + Y+P+ + +V +++ N RW +++L Y F A+T
Sbjct: 1828 ANGILQGYRVVYEPLAPVQGVSKVVTVEVRGNWQRWLKVRDLTKGVTYFFRVQART 1883
Score = 147 bits (370), Expect = 8e-35
Identities = 116/426 (27%), Positives = 196/426 (46%), Gaps = 23/426 (5%)
Query: 619 VSASAVLSVV--DVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYE-----DA 671
V++S + S V D+P P +L +++ +S L + PG D + I+++I+E + D
Sbjct: 1056 VTSSTISSGVPPDLPGAPSNLVISNISPRSATLQFRPGYDGKTSISRWIVEGQVGAIGDE 1115
Query: 672 MHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPD 731
L+ + E Q L+PY +Y FR+ VN +G S S +S T + PD
Sbjct: 1116 EEWVTLYEEENEPDA-QMLEIPNLTPYTHYRFRMKQVNIVGPSPYSPSSRVIQTLQAPPD 1174
Query: 732 KNPTAVEGLGSEPDNLVITWKPLNGFESNG--PGLQYKVSWRQKDGDDEWTSVVVAN--V 787
PT+V + +L + W PL + NG + Y++ + + D + VV++
Sbjct: 1175 VAPTSVTVRTASETSLRLRWVPLPDSQYNGNPESVGYRIKYWRSDLQSSAVAQVVSDRLE 1234
Query: 788 SKYIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAE 847
++ + ++ Y +++QA N +G P VV G + E +P AP NV V+ST
Sbjct: 1235 REFTIEELEEWMEYELQMQAFNAVGAGPWSEVVRGRTRESVPSAAPENVSAEAVSSTQIL 1294
Query: 848 VHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTH-GMLPGLEPFS 906
+ W VP + G + GY+I + + + R HI +G+ T +L GL F
Sbjct: 1295 LTWTSVPEQDQNGLILGYKILF-RAKDLDPEPRSHI------VRGNHTQSALLAGLRKFV 1347
Query: 907 HYTLNVRVVNGKGEG-PASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDPPSHPNGI 965
Y L V G G P++P + T + P P L L S+ + W PP PNGI
Sbjct: 1348 LYELQVLAFTRIGNGVPSTPLILERTKDDAPGPPVRLVFPEVRLTSVRIVWQPPEEPNGI 1407
Query: 966 LTEYTLKYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQIT 1025
+ Y + Y+ +S+ +++ A ++T +L + Y F A+T G G +
Sbjct: 1408 ILGYQIAYRLASSSPH--TFTTVEVGATVRQFTATDLAPESAYIFRLSAKTRQGWGEPLE 1465
Query: 1026 EEAVTT 1031
+TT
Sbjct: 1466 ATVITT 1471
Score = 105 bits (263), Expect = 2e-22
Identities = 114/421 (27%), Positives = 172/421 (40%), Gaps = 37/421 (8%)
Query: 629 DVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQ 688
D P PP L + SV++ W P ++ N I + I Y A P H T V
Sbjct: 1376 DAPGPPVRLVFPEVRLTSVRIVWQPPEEPNGIILGYQIAYRLASSSP---HTFTTVEVGA 1432
Query: 689 TTAQLK---LSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEP-DKNPTAVEGLGSEP 744
T Q L+P Y FR+ A G P EA+ K P V
Sbjct: 1433 TVRQFTATDLAPESAYIFRLSAKTRQGWGEPLEATVITTEKRERPAPPRELLVPQAEVTA 1492
Query: 745 DNLVITWKPLNGFESNGPGLQYKVSWRQKDGDD--EWTSVVVANVSKYIVSGTPTFVPYL 802
+L + W P G + P + + R+ + ++S + + +V F Y
Sbjct: 1493 RSLRLQWVP--GSDGASPIRYFTMQVRELPRGEWQTYSSSISHEATACVVDRLRPFTSYK 1550
Query: 803 IKVQALNDMG---FAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIR 859
++++A ND+G F+ E V + +D+P PG+V ++ + W P +S+
Sbjct: 1551 LRLKATNDIGDSDFSSETEAVT--TLQDVPGEPPGSVSATPHTTSSVLIQWQPPRDESLN 1608
Query: 860 GHLQGYRIYYWK--------TQSSSKRN--RRHIE----KKILTFQGSKTHGM--LPGLE 903
G LQGYRIYY + T++ + +N H E T S T M L L+
Sbjct: 1609 GLLQGYRIYYRELEYEAGSGTEAKTLKNPIALHAELTAQSSFKTVNSSSTSTMCELTHLK 1668
Query: 904 PFSHYTLNVRVVNGKGEGPAS-PDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWD--PPS 960
+ Y + + N GE PAS P VF AP ++++ T L + WD PP
Sbjct: 1669 KYRRYEVIMTAYNIIGESPASAPVEVFVGEAAPAMAPQNVQVTPLTASQLEVTWDPPPPE 1728
Query: 961 HPNGILTEYTLKYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGS 1020
NG + Y + Y +S +E + L +P R LKNL T+Y A +AG
Sbjct: 1729 SQNGNIQGYKIYYWEADSQNETEKMKVLFLPEPVVR--LKNLTSHTKYLVSISAFNAAGD 1786
Query: 1021 G 1021
G
Sbjct: 1787 G 1787
Score = 92.8 bits (229), Expect = 2e-18
Identities = 135/595 (22%), Positives = 225/595 (37%), Gaps = 66/595 (11%)
Query: 618 SVSASAVLSVVDVPN-PPFDLELTDQLDKSVQLSWTPGDDN--NSPITKFIIEYEDAMHK 674
S AV ++ DVP PP + T SV + W P D N + + I Y + ++
Sbjct: 1565 SSETEAVTTLQDVPGEPPGSVSATPHTTSSVLIQWQPPRDESLNGLLQGYRIYYRELEYE 1624
Query: 675 PGLWHHQTEV---------------------SGTQTTAQLK-LSPYVNYSFRVMAVNSIG 712
G + S T T +L L Y Y + A N IG
Sbjct: 1625 AGSGTEAKTLKNPIALHAELTAQSSFKTVNSSSTSTMCELTHLKKYRRYEVIMTAYNIIG 1684
Query: 713 KSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVSWRQ 772
+S S E ++ +A+ P P V+ L +TW P NG YK+ + +
Sbjct: 1685 ESPASAPVEVFVGEAA-PAMAPQNVQVTPLTASQLEVTWDPPPPESQNGNIQGYKIYYWE 1743
Query: 773 KDGDDEWTSVVVANVSKYIV--SGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPM 830
D +E + V + + +V + YL+ + A N G P+ G + + P
Sbjct: 1744 ADSQNETEKMKVLFLPEPVVRLKNLTSHTKYLVSISAFNAAGDGPKSDPQQGRTHQAAPG 1803
Query: 831 VAPGNVRVNVVNSTLAEVHW-DPVPLKSIRGHLQGYRIYYWK---TQSSSKRNRRHIEKK 886
AP + + + ST V W +P + G LQGYR+ Y Q SK +E +
Sbjct: 1804 -APSFLAFSEITSTTLNVSWGEPA---AANGILQGYRVVYEPLAPVQGVSKVVT--VEVR 1857
Query: 887 ILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNTP-EGVPSAPSSLKIV 945
+ K + G+ F + + R + GP + P EG P +P + +V
Sbjct: 1858 GNWQRWLKVRDLTKGVTYF--FRVQARTIT---YGPELQANITAGPAEGSPGSPRDV-LV 1911
Query: 946 NPTLDSLTLEWDPPSHPNGILTEYTLKYQPINSTHELGPLVDLKIPANKTRWTLK--NLN 1003
+ LTL+W + T Y ++ +P S L + IP + T +TL L
Sbjct: 1912 TKSASELTLQWTEGHSGDTPTTGYVIEARP--SDEGLWDMFVKDIPRSATSYTLSLDKLR 1969
Query: 1004 FSTRYKFYFYAQTSAGSGSQITEEAVTTVDEAMASRQVDIATQGWFIGLMCAVALLILIL 1063
Y+F A AG G + A + + WF+ +M +L++++L
Sbjct: 1970 QGVTYEFRVVAVNEAGYGEPSNPSTAVS-----AQVEAPFYEEWWFLLVMALSSLIVILL 2024
Query: 1064 LIVCFIRRNKGGKYPVKEKEDAHADPEIQPMKE----DDGTFGEYSDAEDHKPLKKGSRT 1119
++ + + KY ++ I M+E D+G F + H +K
Sbjct: 2025 VVFALVLHGQNKKY-----KNCSTGKGISTMEESVTLDNGGFAALELSSRHLNVKSTFSK 2079
Query: 1120 PSDRTVKKEDSDDSLVDYGEGVNGQFNEDGSFIGQYSGKKEKEPAEGNESSEAPS 1174
+ S L E + ++N G+ + + KEK A+ +ES S
Sbjct: 2080 KNGTRSPPRPSPGGLHYSDEDICNKYN--GAVLTESVSLKEKS-ADASESEATDS 2131
Score = 84.7 bits (208), Expect = 5e-16
Identities = 168/795 (21%), Positives = 304/795 (38%), Gaps = 91/795 (11%)
Query: 277 LRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIA 336
L GN L L C+AEG W ++D L + YK +LQ + D+G Y+C+
Sbjct: 117 LEGNRLVLTCLAEGSWPLEFKWMRDDSELTTYSSEYKYIIPSLQ-----KLDAGFYRCVV 171
Query: 337 KNALGA-IHHTISVRVKAAPYWITAPQNLVLSPGEDGTL-ICRANGNPKPRISWLTNGVP 394
+N +GA + V+V ++ Q +S G L + P+P+++W G
Sbjct: 172 RNRMGALLQRKSEVQVAYMGSFMDTDQRKTVSQGRAAILNLLPITSYPRPQVTWFREGHK 231
Query: 395 IEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNV-----LAEP-- 447
I I + + ++ +I + + A Y + + G + F+++ + P
Sbjct: 232 I-IPSNRIAITLENQLVILATTTSDAGAYYVQAVNEKNGENKTSPFIHLSIARDVGTPET 290
Query: 448 --PRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLE 505
P I+ P V + L+C P+ + G + ++ T+
Sbjct: 291 MAPTIVVPPGNRSVVAGSSETTLECIASARPVEDLSVTWKRNGVRITSGLHSFGRRLTIS 350
Query: 506 IPVAQKDSTGTYTCVAR---NKLGMAKNEVHLEIKDPTWIVKQPEYAV-VQRGSMVSFEC 561
P + TG Y C A + A+ L I +P + +PE + + V C
Sbjct: 351 NPTSA--DTGPYVCEAALPGSAFEPARATAFLFIIEPPYFTAEPESRISAEVEETVDIGC 408
Query: 562 KVKHDHTLSLTVLWLKDN---RELPSDERFTVDKDHLVVADVSDDDSGTYTCVANTTLDS 618
+ T+ W KD L + + L + + +DSG + C A+
Sbjct: 409 QAM--GVPLPTLQWYKDAISISRLQNPRYKVLASGGLRIQKLRPEDSGIFQCFASNEGGE 466
Query: 619 VSASAVLSVVDV----PNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHK 674
+ L V ++ P D +TD + ++ + + +P + E+ +
Sbjct: 467 IQTHTYLDVTNIAPVFTQRPVDTTVTDGMTAILRC-----EVSGAPKPAITWKRENHILA 521
Query: 675 PG---LWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKAS--E 729
G + SG A + + NY+ A N+ G SL + A+ + S
Sbjct: 522 SGSVRIPRFMLLESGGLQIAPVFIQDAGNYT--CYAANTEG-SLNASATLTVWNRTSIVH 578
Query: 730 PDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVSWRQKD---GDDEWTSVVVAN 786
P ++ ++G T L+ ++ P + + W++ + + +VV
Sbjct: 579 PPEDHVVIKG----------TTATLHCGATHDPRVSLRYVWKKDNVALTPSSTSRIVVEK 628
Query: 787 VSKYIVSGT--PTFVPYLIKV--QALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVN 842
++S T Y ++ + ND A + + HS ++L +V+P N
Sbjct: 629 DGSLLISQTWSGDIGDYSCEIVSEGGNDSRMARLEVIELPHSPQNL-LVSP--------N 679
Query: 843 STLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGM-LPG 901
S+ H V L +R I Y+ + S + + L+ G + G+ + G
Sbjct: 680 SS----HSHAVVLSWVRPFDGNSPILYYIVELSENNSPWKVH---LSNVGPEMTGVTVSG 732
Query: 902 LEPFSHYTLNVRVVN--GKGEGPASPDRVFNTPEGVPSA-PSSLKIVNPTLDSLTLEWDP 958
L P Y V VN G+G+ A R+ PE PSA P ++ T S+ ++W P
Sbjct: 733 LTPARTYQFRVCAVNEVGRGQYSAETSRLM-LPEEPPSAPPKNIVASGRTNQSIMVQWQP 791
Query: 959 P--SHPNGILTEYTLKYQPINSTHELGPLVDLKIPANKTRWTL-KNLNFSTRYKFYFYAQ 1015
P + NG+L Y L+Y+ G I + + + L +L T+Y+ A
Sbjct: 792 PPETEHNGVLRGYILRYRLAGLP---GEYQQRNITSPEVNYCLVTDLIIWTQYEIQVAAY 848
Query: 1016 TSAGSGSQITEEAVT 1030
AG G + AVT
Sbjct: 849 NGAGLG--VFSRAVT 861
Score = 65.9 bits (159), Expect = 2e-10
Identities = 77/342 (22%), Positives = 133/342 (38%), Gaps = 50/342 (14%)
Query: 34 LDLVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKP 93
L +++PP T + + E + I C+A G P P+ W ++ ++P +
Sbjct: 380 LFIIEPPYFTAEPESRISAEVEETVDIGCQAMGVPLPTLQWYKDAISISRLQNPRYKVLA 439
Query: 94 GTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQS 153
G I + E G++QC A NE G ++ + + +P++T+ ++ T+
Sbjct: 440 SGGLRIQKLRPED-----SGIFQCFASNEGGEIQTHTYLDVTNIAPVFTQRPVD-TTVTD 493
Query: 154 GQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGL---NGDLYFSNVLPEDTREDY 210
G + +L C G P P I W + S R+ + + +G L + V +D +Y
Sbjct: 494 GMTAILRCEVS-GAPKPAITWKRENHILASGSVRIPRFMLLESGGLQIAPVFIQDA-GNY 551
Query: 211 ICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGN 270
CYA N + N S T ++S PP
Sbjct: 552 TCYA-----------------------ANTEGSLNASATLTVWNRTSIVHPP-------- 580
Query: 271 ASNKEELRGNVLSLECIAEGLPTPII--YWAKEDGMLPKNRTVYKNFEK--TLQIIHVSE 326
+ ++G +L C A P + W K++ L + T EK +L I
Sbjct: 581 -EDHVVIKGTTATLHCGATHDPRVSLRYVWKKDNVALTPSSTSRIVVEKDGSLLISQTWS 639
Query: 327 ADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSP 368
D G+Y C + G + V P+ +PQNL++SP
Sbjct: 640 GDIGDYSCEIVSEGGNDSRMARLEVIELPH---SPQNLLVSP 678
>gi|20127422 Down syndrome cell adhesion molecule isoform CHD2-42
precursor [Homo sapiens]
Length = 2012
Score = 229 bits (583), Expect = 2e-59
Identities = 279/1128 (24%), Positives = 451/1128 (39%), Gaps = 117/1128 (10%)
Query: 37 VQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTG 96
V+ P SP+ + + C G SW RNG + K+ +T G
Sbjct: 310 VKQPLKATISPRKVKSSVGSQVSLSCSVTGTEDQELSWYRNGEILNPGKNVRIT-----G 364
Query: 97 TLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQS 156
N++ + ++ G YQC R ++ +A VV +P E + + +
Sbjct: 365 INHENLIMDHMVKSDGGAYQCFVRKDKLSAQDYVQVVLEDGTPKIISAFSEKV-VSPAEP 423
Query: 157 LVLPCRPPIGLPPPIIFW-MDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYAR 215
+ L C G P P I W +D+ S R+SQ + + NV + Y
Sbjct: 424 VSLMCNVK-GTPLPTITWTLDDDPILKGGSHRISQMITSE---GNV---------VSYLN 470
Query: 216 FNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKE 275
+ +Q + + A N + Y A+ + R P + P N +
Sbjct: 471 ISSSQ------------VRDGGVYRCTANNSAGVVLYQARIN-VRGPASIRPMKNIT--- 514
Query: 276 ELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKN-RTVYKNFEKTLQIIHVS-EADSGNYQ 333
+ G + C G P I W K +LP N R V TL++ V E D G Y
Sbjct: 515 AIAGRDTYIHCRVIGYPYYSIKWYKNSNLLPFNHRQVAFENNGTLKLSDVQKEVDEGEYT 574
Query: 334 C-IAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKP-RISWLTN 391
C + + ++ V VK P+ I + S G+ + C P I+W +
Sbjct: 575 CNVLVQPQLSTSQSVHVTVKVPPF-IQPFEFPRFSIGQRVFIPCVVVSGDLPITITWQKD 633
Query: 392 GVPIEIAPDDPSRKID-GDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRI 450
G PI + ID ++ SN+ + Y C A NE + + + V P +
Sbjct: 634 GRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFV 693
Query: 451 LTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGS--------ALHEDIYVLHENG 502
+ P + I + +L+C+ G P+PTI W K +KG+ AL+ I VL NG
Sbjct: 694 VQPRDQ--DGIYGKAVILNCSAEGYPVPTIVW-KFSKGAGVPQFQPIALNGRIQVL-SNG 749
Query: 503 TLEIPVAQKDSTGTYTCVARNKLGM-AKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFEC 561
+L I ++ +G Y C N +G ++L +K P I P + +G C
Sbjct: 750 SLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLTVKIPAMITSYPNTTLATQGQKKEMSC 809
Query: 562 KVKHDHTLSLTVLWLKDNREL-PSDERFTVDKDH--------LVVADVSDDDSGTYTCVA 612
+ + V W K++R + P R+ V L + +DSG ++C A
Sbjct: 810 TAHGEKPI--IVRWEKEDRIINPEMARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHA 867
Query: 613 NTTLDSVSASAVLSVVDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAM 672
+ L+V + P+PP ++E+ D +++ L WT G D NSPIT + IE ++
Sbjct: 868 INSYGEDRGIIQLTVQEPPDPP-EIEIKDVKARTITLRWTMGFDGNSPITGYDIECKNKS 926
Query: 673 HKPGLWHHQTEVSGTQTTAQL-KLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPD 731
+VS +A + + P YS R+ A N IGKS PS +A+ PD
Sbjct: 927 DSWDSAQRTKDVSPQLNSATIIDIHPSSTYSIRMYAKNRIGKSEPSNELTITADEAA-PD 985
Query: 732 KNPTAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVSWRQ-KDGDDEWTSVVVANVSK- 789
P V ++ +TWK NG Y++ +R+ G + +++ + S
Sbjct: 986 GPPQEVHLEPISSQSIRVTWKAPKKHLQNGIIRGYQIGYREYSTGGNFQFNIISVDTSGD 1045
Query: 790 ---YIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLA 846
Y + F Y + VQA N G P ++ + ED+P P NV+ +
Sbjct: 1046 SEVYTLDNLNKFTQYGLVVQACNRAGTGPSSQEIITTTLEDVPSYPPENVQAIATSPESI 1105
Query: 847 EVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFS 906
+ W + +++ G LQG+R+ YW + K I T Q S L GLE ++
Sbjct: 1106 SISWSTLSKEALNGILQGFRVIYWANLMDGELGE---IKNITTTQPSLE---LDGLEKYT 1159
Query: 907 HYTLNVRVVNGKGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDPPSHPNGIL 966
+Y++ V G+G S T E VP P+ +K + + + W PP NGI+
Sbjct: 1160 NYSIQVLAFTRAGDGVRSEQIFTRTKEDVPGPPAGVKAAAASASMVFVSWLPPLKLNGII 1219
Query: 967 TEYTL----KYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSGS 1022
+YT+ Y + S E P + + + NL+ + +Y + A TSAG G+
Sbjct: 1220 RKYTVFCSHPYPTVISEFEASP--------DSFSYRIPNLSRNRQYSVWVVAVTSAGRGN 1271
Query: 1023 QITEEAVTTVDEAMASRQVDIATQGWFIGLMCAVALLILILLIVCFIRRNKGGKYPVKEK 1082
+ E +T E +A I T F G + + ++L P K
Sbjct: 1272 --SSEIITV--EPLAKAPARILT---FSGTVTTPWMKDIVL--------------PCKAV 1310
Query: 1083 EDAHADPEIQPMKEDDGTFGEYSDAEDHKPLKKGSRTPSDRTVKKEDS 1130
D P ++ MK+ +GT + GS RTVK EDS
Sbjct: 1311 GD--PSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFI--IRTVKAEDS 1354
Score = 147 bits (370), Expect = 8e-35
Identities = 238/1029 (23%), Positives = 376/1029 (36%), Gaps = 132/1029 (12%)
Query: 56 ENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVY 115
+ + + C+A G P P + W ++ ++ K TG LI NI G Y
Sbjct: 240 QRVELPCKALGHPEPDYRWLKDNMPLELSGR---FQKTVTGLLIENIRPSD-----SGSY 291
Query: 116 QCTARNERGAA-VSNNIVVRPSRSPLWTKEKLEPITLQS--GQSLVLPCRPPIGLPPPII 172
C N G A V + V + PL K + P ++S G + L C G +
Sbjct: 292 VCEVSNRYGTAKVIGRLYV---KQPL--KATISPRKVKSSVGSQVSLSC-SVTGTEDQEL 345
Query: 173 FWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKV 232
W N P G+N + + + + Y C+ R + V+V
Sbjct: 346 SWYRNGEILNPGKNVRITGINHENLIMDHMVKSDGGAYQCFVRKDKLSAQDY-----VQV 400
Query: 233 ISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLP 292
+ D I+A S K +SL C +G P
Sbjct: 401 VLEDGTPKIISA--------------------------FSEKVVSPAEPVSLMCNVKGTP 434
Query: 293 TPIIYWAKEDGMLPKNR--------TVYKNFEKTLQIIHVSEADSGNYQCIAKNALGAIH 344
P I W +D + K T N L I D G Y+C A N+ G +
Sbjct: 435 LPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVL 494
Query: 345 HTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSR 404
+ + V+ P I +N+ G D + CR G P I W N + +
Sbjct: 495 YQARINVR-GPASIRPMKNITAIAGRDTYIHCRVIGYPYYSIKWYKNSNLLPFNHRQVAF 553
Query: 405 KIDGDTIIFSNVQ-ERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIAN 463
+ +G T+ S+VQ E Y CN + L + V+V + P + P I
Sbjct: 554 ENNG-TLKLSDVQKEVDEGEYTCNVLVQ-PQLSTSQSVHVTVKVPPFIQPFEFPRFSIGQ 611
Query: 464 RPALLDCAFFGSPLP-TIEWFKGAK--GSALHEDIYVLHENGTLEIPVAQKDSTGTYTCV 520
R + C LP TI W K + +L I + +L I G YTC+
Sbjct: 612 R-VFIPCVVVSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCI 670
Query: 521 ARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLW----- 575
ARN+ +++ L ++ P V QP G V C + T++W
Sbjct: 671 ARNEAAAVEHQSQLIVRVPPKFVVQPRDQDGIYGKAVILNCSAEGYPV--PTIVWKFSKG 728
Query: 576 --LKDNRELPSDERFTV-DKDHLVVADVSDDDSGTYTC-VANTTLDSVSASAVLSV---- 627
+ + + + R V L++ V ++DSG Y C V+N VS S L+V
Sbjct: 729 AGVPQFQPIALNGRIQVLSNGSLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLTVKIPA 788
Query: 628 --VDVPNPPF-------DLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLW 678
PN ++ T +K + + W E ED + P +
Sbjct: 789 MITSYPNTTLATQGQKKEMSCTAHGEKPIIVRW---------------EKEDRIINPEMA 833
Query: 679 HH--QTEVSGTQTTAQLKLSPYVNYS---FRVMAVNSIGKSLPSEASEQYLTKASEPDKN 733
+ T+ G + + L++ P V F A+NS G+ + LT PD
Sbjct: 834 RYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAINSYGE----DRGIIQLTVQEPPD-- 887
Query: 734 PTAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDEWTSVV-VANVSKYIV 792
P +E + + + W GF+ N P Y + + K D W S +VS +
Sbjct: 888 PPEIEIKDVKARTITLRW--TMGFDGNSPITGYDIECKNK--SDSWDSAQRTKDVSPQLN 943
Query: 793 SGTPTFV----PYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEV 848
S T + Y I++ A N +G + + + E P P V + ++S V
Sbjct: 944 SATIIDIHPSSTYSIRMYAKNRIGKSEPSNELTITADEAAPDGPPQEVHLEPISSQSIRV 1003
Query: 849 HWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHY 908
W G ++GY+I Y + + I + G L L F+ Y
Sbjct: 1004 TWKAPKKHLQNGIIRGYQIGYREYSTGGNFQFNIIS---VDTSGDSEVYTLDNLNKFTQY 1060
Query: 909 TLNVRVVNGKGEGPASPDRVFNTPEGVPS-APSSLKIVNPTLDSLTLEWDPPSHP--NGI 965
L V+ N G GP+S + + T E VPS P +++ + + +S+++ W S NGI
Sbjct: 1061 GLVVQACNRAGTGPSSQEIITTTLEDVPSYPPENVQAIATSPESISISWSTLSKEALNGI 1120
Query: 966 LTEYTLKYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQIT 1025
L + + Y ELG + + I + L L T Y A T AG G + +
Sbjct: 1121 LQGFRVIYWANLMDGELGEIKN--ITTTQPSLELDGLEKYTNYSIQVLAFTRAGDGVR-S 1177
Query: 1026 EEAVTTVDE 1034
E+ T E
Sbjct: 1178 EQIFTRTKE 1186
Score = 145 bits (366), Expect = 2e-34
Identities = 197/885 (22%), Positives = 340/885 (38%), Gaps = 103/885 (11%)
Query: 30 LEVPLDLVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLV 89
++V L+ P I+ S K ++ P E + + C KG P P+ +WT +D DP+
Sbjct: 398 VQVVLEDGTPKIISAFSEK--VVSPAEPVSLMCNVKGTPLPTITWT-------LDDDPI- 447
Query: 90 TMKPGTGTLIINIMSEGKAETY----------EGVYQCTARNERGAAV-SNNIVVRPSRS 138
+K G+ + I SEG +Y GVY+CTA N G + I VR S
Sbjct: 448 -LKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRGPAS 506
Query: 139 PLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSER-VSQGLNGDLY 197
++ IT +G+ + CR IG P I W NS LP + R V+ NG L
Sbjct: 507 ----IRPMKNITAIAGRDTYIHCR-VIGYPYYSIKWYKNS-NLLPFNHRQVAFENNGTLK 560
Query: 198 FSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSS 257
S+V E +Y C + Q ++VKV
Sbjct: 561 LSDVQKEVDEGEYTCNVLVQPQLSTSQSVHVTVKV------------------------- 595
Query: 258 RERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPI-IYWAKEDGMLPKNRTV---YK 313
P F+ P G + + C+ PI I W K+ +P + V
Sbjct: 596 ----PPFIQP---FEFPRFSIGQRVFIPCVVVSGDLPITITWQKDGRPIPGSLGVTIDNI 648
Query: 314 NFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGT 373
+F +L+I ++S +GNY CIA+N A+ H + V+ P ++ P++ G+
Sbjct: 649 DFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVVQPRDQDGIYGKAVI 708
Query: 374 LICRANGNPKPRISWLTN---GVP--IEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNA 428
L C A G P P I W + GVP IA + + + +++ +V E S Y C
Sbjct: 709 LNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQVLSNGSLLIKHVVEEDSGYYLCKV 768
Query: 429 SNEYGYLLANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKG 488
SN+ G ++ + + P I + NT + + C G + W K +
Sbjct: 769 SNDVGADVSKSMYLTVKIPAMITSYPNTTLATQGQKKE-MSCTAHGEKPIIVRWEKEDRI 827
Query: 489 SALHEDIYVLHEN-------GTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTW 541
Y++ TL+I ++ +G ++C A N G + + L +++P
Sbjct: 828 INPEMARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEPP- 886
Query: 542 IVKQPEYAVVQ-RGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKD------H 594
PE + + ++ + D +T ++ + S + KD
Sbjct: 887 --DPPEIEIKDVKARTITLRWTMGFDGNSPITGYDIECKNKSDSWDSAQRTKDVSPQLNS 944
Query: 595 LVVADVSDDDSGTYTCVANTTLDSVSASAVLSV----VDVPNPPFDLELTDQLDKSVQLS 650
+ D+ + + A + S L++ PP ++ L +S++++
Sbjct: 945 ATIIDIHPSSTYSIRMYAKNRIGKSEPSNELTITADEAAPDGPPQEVHLEPISSQSIRVT 1004
Query: 651 WTPGDDN--NSPITKFIIEYEDAMHKPGLWHH--QTEVSGTQTTAQL-KLSPYVNYSFRV 705
W + N I + I Y + + + SG L L+ + Y V
Sbjct: 1005 WKAPKKHLQNGIIRGYQIGYREYSTGGNFQFNIISVDTSGDSEVYTLDNLNKFTQYGLVV 1064
Query: 706 MAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGLQ 765
A N G PS T P P V+ + + P+++ I+W L+ NG
Sbjct: 1065 QACNRAGTG-PSSQEIITTTLEDVPSYPPENVQAIATSPESISISWSTLSKEALNGILQG 1123
Query: 766 YKVSW--RQKDGDDEWTSVVVANVSKYIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGH 823
++V + DG+ + + G + Y I+V A G +
Sbjct: 1124 FRVIYWANLMDGELGEIKNITTTQPSLELDGLEKYTNYSIQVLAFTRAGDGVRSEQIFTR 1183
Query: 824 SGEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIY 868
+ ED+P P V+ ++++ V W P PLK + G ++ Y ++
Sbjct: 1184 TKEDVP-GPPAGVKAAAASASMVFVSWLP-PLK-LNGIIRKYTVF 1225
Score = 112 bits (281), Expect = 2e-24
Identities = 143/597 (23%), Positives = 230/597 (38%), Gaps = 61/597 (10%)
Query: 59 VIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAET--YEGVYQ 116
++ C A G PP + W T +I P + GTL I T ++ Y
Sbjct: 43 LVPCPAAGIPPVTLRWYL-ATGEEIYDVPGIRHVHPNGTLQIFPFPPSSFSTLIHDNTYY 101
Query: 117 CTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPP--PIIFW 174
CTA N G S ++ ++ +T + T++ G V C P + ++ W
Sbjct: 102 CTAENPSGKIRSQDVHIKAVLREPYTVRVEDQKTMR-GNVAVFKCIIPSSVEAYITVVSW 160
Query: 175 MDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVIS 234
++ L R G LY +V ED +Y C R H T + +Q S ++
Sbjct: 161 EKDTVS-LVSGSRFLITSTGALYIKDVQNEDGLYNYRCITR--HRYTGETRQSNSARLFV 217
Query: 235 VDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTP 294
D N P+ L +++ + G + L C A G P P
Sbjct: 218 SDPANSA--------------------PSILD---GFDHRKAMAGQRVELPCKALGHPEP 254
Query: 295 IIYWAKEDGMLPKNRTVYKNFEKT---LQIIHVSEADSGNYQCIAKNALGAIHHTISVRV 351
W K++ L + F+KT L I ++ +DSG+Y C N G + V
Sbjct: 255 DYRWLKDNMPLELSG----RFQKTVTGLLIENIRPSDSGSYVCEVSNRYGTAKVIGRLYV 310
Query: 352 KAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTI 411
K +P+ + S G +L C G +SW NG + + I+ + +
Sbjct: 311 KQPLKATISPRKVKSSVGSQVSLSCSVTGTEDQELSWYRNGEILNPGKNVRITGINHENL 370
Query: 412 IFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAE--PPRILTPANTLYQVIANRPALLD 469
I ++ + YQC + L A +V V+ E P+I++ A + V P L
Sbjct: 371 IMDHMVKSDGGAYQCFVRKD--KLSAQDYVQVVLEDGTPKIIS-AFSEKVVSPAEPVSLM 427
Query: 470 CAFFGSPLPTIEWFKG----AKGSALHEDIYVLHENGT----LEIPVAQKDSTGTYTCVA 521
C G+PLPTI W KG + H ++ G L I +Q G Y C A
Sbjct: 428 CNVKGTPLPTITWTLDDDPILKGGS-HRISQMITSEGNVVSYLNISSSQVRDGGVYRCTA 486
Query: 522 RNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRE 581
N G+ + + ++ P I + G C+V S + W K++
Sbjct: 487 NNSAGVVLYQARINVRGPASIRPMKNITAI-AGRDTYIHCRVIGYPYYS--IKWYKNSNL 543
Query: 582 LPSDERFTVDKDH--LVVADVSDD-DSGTYTCVANTTLDSVSASAVLSVVDVPNPPF 635
LP + R +++ L ++DV + D G YTC N + +++ V V PPF
Sbjct: 544 LPFNHRQVAFENNGTLKLSDVQKEVDEGEYTC--NVLVQPQLSTSQSVHVTVKVPPF 598
Score = 64.3 bits (155), Expect = 7e-10
Identities = 72/281 (25%), Positives = 118/281 (41%), Gaps = 25/281 (8%)
Query: 561 CKVKHDHTLSLTVLWLKDNRELPS-----DERFTVDKDHLVVADVSDDDSGTYTCVANTT 615
CK D S V W+KD+ PS R ++ V +DSG Y+C+AN
Sbjct: 1307 CKAVGDP--SPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYSCIANNN 1364
Query: 616 LDSVSASAVLSVVDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEY-EDAMHK 674
S L V P+ P L ++ S+ LSW PGD+ S I +I++Y ED +
Sbjct: 1365 WGSDEIILNLQVQVPPDQP-RLTVSKTTSSSITLSWLPGDNGGSSIRGYILQYSEDNSEQ 1423
Query: 675 PGLWHHQTEVSGTQTTAQLK-LSPYVNYSFRVMAVNSIGKSLPSEASE-QYLTKASEPDK 732
G + +S ++ + +L+ L Y F + A N +G SE E + L K + K
Sbjct: 1424 WGSF----PISPSERSYRLENLKCGTWYKFTLTAQNGVGPGRISEIIEAKTLGKEPQFSK 1479
Query: 733 NPTAVEGLGSEPDNL-VITWKPLNGFESNGPGLQYKVSWRQKDGDDEWTSVVVANVSK-Y 790
+ + L +I W + P + + +R G WT+ ++SK Y
Sbjct: 1480 EQELFASINTTRVRLNLIGWN-----DGGCPITSFTLEYR-PFGTTVWTTAQRTSLSKSY 1533
Query: 791 IVSGTPTFVPYLIKVQALNDMGFAPEPA--VVMGHSGEDLP 829
I+ Y ++++ N G A + A + + G +P
Sbjct: 1534 ILYDLQEATWYELQMRVCNSAGCAEKQANFATLNYDGSTIP 1574
Score = 55.8 bits (133), Expect = 2e-07
Identities = 83/370 (22%), Positives = 142/370 (38%), Gaps = 59/370 (15%)
Query: 3 LKIMPKKKRLSAGRVPL-ILFLCQMISALEVPLDLVQPPTITQQSPKDYIIDPRENIVIQ 61
LK+ +K + G +L Q+ ++ V + + PP I + I R + I
Sbjct: 559 LKLSDVQKEVDEGEYTCNVLVQPQLSTSQSVHVTVKVPPFIQPFEFPRFSIGQR--VFIP 616
Query: 62 CEA-KGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQCTAR 120
C G P + +W ++G + T +L I+ +S + G Y C AR
Sbjct: 617 CVVVSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSLRISNLSL----MHNGNYTCIAR 672
Query: 121 NERGAAV-SNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDN-- 177
NE A + ++VR + + I G++++L C G P P I W +
Sbjct: 673 NEAAAVEHQSQLIVRVPPKFVVQPRDQDGI---YGKAVILNCSAE-GYPVPTIVWKFSKG 728
Query: 178 ----SFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVI 233
FQ + + R+ NG L +V+ ED+ Y+C
Sbjct: 729 AGVPQFQPIALNGRIQVLSNGSLLIKHVVEEDSGY-YLC--------------------- 766
Query: 234 SVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPT 293
++++ + A++S + + K P +T N + + G + C A G
Sbjct: 767 ---KVSNDVGADVSKSMYLTVKI-----PAMITSYPNTTLATQ--GQKKEMSCTAHGEKP 816
Query: 294 PIIYWAKEDGM--------LPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGAIHH 345
I+ W KED + L + V + TLQI+ DSG + C A N+ G
Sbjct: 817 IIVRWEKEDRIINPEMARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRG 876
Query: 346 TISVRVKAAP 355
I + V+ P
Sbjct: 877 IIQLTVQEPP 886
Score = 50.1 bits (118), Expect = 1e-05
Identities = 98/441 (22%), Positives = 168/441 (38%), Gaps = 69/441 (15%)
Query: 629 DVPN-PPFDLELTDQLDKSVQLSWTPGDDN--NSPITKFIIEYEDAMHKPGLWHHQTEVS 685
DVP+ PP +++ +S+ +SW+ N + F + Y A G ++
Sbjct: 1086 DVPSYPPENVQAIATSPESISISWSTLSKEALNGILQGFRVIYW-ANLMDGELGEIKNIT 1144
Query: 686 GTQTTAQLK-LSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTA-VEGLGSE 743
TQ + +L L Y NYS +V+A G + SEQ T+ E P A V+ +
Sbjct: 1145 TTQPSLELDGLEKYTNYSIQVLAFTRAGDGV---RSEQIFTRTKEDVPGPPAGVKAAAAS 1201
Query: 744 PDNLVITWKP---LNGFESNGPGL---QYKVSWRQKDGDDEWTSVVVANVSKYIVSGTPT 797
+ ++W P LNG Y + + + S + N+S+
Sbjct: 1202 ASMVFVSWLPPLKLNGIIRKYTVFCSHPYPTVISEFEASPDSFSYRIPNLSRNR------ 1255
Query: 798 FVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPM--VAPGNVRVNVVNSTLAEVHWDPV-- 853
Y + V A+ G G+S E + + +A R+ + T+ +
Sbjct: 1256 --QYSVWVVAVTSAG--------RGNSSEIITVEPLAKAPARILTFSGTVTTPWMKDIVL 1305
Query: 854 PLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVR 913
P K++ + W S+ + ++T G ++ FS+ + +R
Sbjct: 1306 PCKAVGDPSPAVK---WMKDSNGTPS-------LVTIDGRRSI--------FSNGSFIIR 1347
Query: 914 VVNGKGEGP---------ASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDPPSHPNG 964
V + G S + + N VP L + T S+TL W P +
Sbjct: 1348 TVKAEDSGYYSCIANNNWGSDEIILNLQVQVPPDQPRLTVSKTTSSSITLSWLPGDNGGS 1407
Query: 965 ILTEYTLKYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQI 1024
+ Y L+Y NS + G I ++ + L+NL T YKF AQ G G +I
Sbjct: 1408 SIRGYILQYSEDNS-EQWG---SFPISPSERSYRLENLKCGTWYKFTLTAQNGVGPG-RI 1462
Query: 1025 TE--EAVTTVDEAMASRQVDI 1043
+E EA T E S++ ++
Sbjct: 1463 SEIIEAKTLGKEPQFSKEQEL 1483
Score = 47.0 bits (110), Expect = 1e-04
Identities = 36/148 (24%), Positives = 61/148 (41%), Gaps = 13/148 (8%)
Query: 313 KNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDG 372
+N + ++ ++ V+ A GN I T+ KA +T + +D
Sbjct: 1253 RNRQYSVWVVAVTSAGRGNSSEII---------TVEPLAKAPARILTFSGTVTTPWMKDI 1303
Query: 373 TLICRANGNPKPRISWL--TNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASN 430
L C+A G+P P + W+ +NG P + D + I V+ S Y C A+N
Sbjct: 1304 VLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYSCIANN 1363
Query: 431 EYG--YLLANAFVNVLAEPPRILTPANT 456
+G ++ N V V + PR+ T
Sbjct: 1364 NWGSDEIILNLQVQVPPDQPRLTVSKTT 1391
Score = 44.7 bits (104), Expect = 5e-04
Identities = 63/298 (21%), Positives = 114/298 (38%), Gaps = 59/298 (19%)
Query: 447 PPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDI---YVLHENGT 503
P RILT + T+ + +L C G P P ++W K + G+ I + NG+
Sbjct: 1285 PARILTFSGTVTTPWM-KDIVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGS 1343
Query: 504 LEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFECKV 563
I + + +G Y+C+A N G + ++L+++ P QP V + S
Sbjct: 1344 FIIRTVKAEDSGYYSCIANNNWGSDEIILNLQVQVPP---DQPRLTVSKTTSS------- 1393
Query: 564 KHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVADVSDDDS------------------ 605
S+T+ W LP D + + +++ S+D+S
Sbjct: 1394 ------SITLSW------LPGDNGGSSIRGYIL--QYSEDNSEQWGSFPISPSERSYRLE 1439
Query: 606 ----GTYTCVANTTLDSVSASAVLSVVDV----PNPPF--DLELTDQLDKS-VQLSWTPG 654
GT+ T + V + +++ P F + EL ++ + V+L+
Sbjct: 1440 NLKCGTWYKFTLTAQNGVGPGRISEIIEAKTLGKEPQFSKEQELFASINTTRVRLNLIGW 1499
Query: 655 DDNNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIG 712
+D PIT F +EY +W S +++ L Y ++ NS G
Sbjct: 1500 NDGGCPITSFTLEYRP--FGTTVWTTAQRTSLSKSYILYDLQEATWYELQMRVCNSAG 1555
Score = 39.3 bits (90), Expect = 0.022
Identities = 33/140 (23%), Positives = 59/140 (42%), Gaps = 16/140 (11%)
Query: 222 IQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEELRGNV 281
+ + + SV V++V T A + +E + + P LT G +
Sbjct: 1251 LSRNRQYSVWVVAV-----TSAGRGNSSEIITVEPLAKAPARILTFSGTVTTPWM---KD 1302
Query: 282 LSLECIAEGLPTPIIYWAKEDGMLPK------NRTVYKNFEKTLQIIHVSEADSGNYQCI 335
+ L C A G P+P + W K+ P R+++ N ++ + DSG Y CI
Sbjct: 1303 IVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFIIRTVKAE--DSGYYSCI 1360
Query: 336 AKNALGAIHHTISVRVKAAP 355
A N G+ ++++V+ P
Sbjct: 1361 ANNNWGSDEIILNLQVQVPP 1380
Score = 32.3 bits (72), Expect = 2.7
Identities = 28/95 (29%), Positives = 41/95 (43%), Gaps = 11/95 (11%)
Query: 56 ENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIIN---IMSEGKAETYE 112
++IV+ C+A G P P+ W + D + P + G ++ N I+ KAE
Sbjct: 1301 KDIVLPCKAVGDPSPAVKWMK-----DSNGTPSLVTIDGRRSIFSNGSFIIRTVKAED-S 1354
Query: 113 GVYQCTARNERGA--AVSNNIVVRPSRSPLWTKEK 145
G Y C A N G+ + N V P P T K
Sbjct: 1355 GYYSCIANNNWGSDEIILNLQVQVPPDQPRLTVSK 1389
>gi|21359935 Down syndrome cell adhesion molecule like 1 [Homo
sapiens]
Length = 2113
Score = 229 bits (583), Expect = 2e-59
Identities = 259/1067 (24%), Positives = 424/1067 (39%), Gaps = 119/1067 (11%)
Query: 22 FLCQMI----SALEVPLDLVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRN 77
++C++ SA + +V P +PK +++ C G P + W RN
Sbjct: 352 YICEVTNTFGSAEATGILMVIDPLHVTLTPKKLKTGIGSTVILSCALTGSPEFTIRWYRN 411
Query: 78 GTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSR 137
T + + + TL+I +++ G YQC A + A I+
Sbjct: 412 -TELVLPDEAISIRGLSNETLLIT----SAQKSHSGAYQCFATRKAQTAQDFAIIALEDG 466
Query: 138 SPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFW-MDNSFQRLPQSERVSQGLNGD- 195
+P E + + G+ L C G PPP + W +D+ S R +Q D
Sbjct: 467 TPRIVSSFSEKV-VNPGEQFSLMCAAK-GAPPPTVTWALDDEPIVRDGSHRTNQYTMSDG 524
Query: 196 --LYFSNVLPEDTRED--YICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEF 251
+ NV R+ Y C AR NL +
Sbjct: 525 TTISHMNVTGPQIRDGGVYRCTAR-----------------------------NLVGSAE 555
Query: 252 YGAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKN--R 309
Y A+ + PP+ N + G + C G P I W K+ +LP N +
Sbjct: 556 YQARINVRGPPSIRAMR----NITAVAGRDTLINCRVIGYPYYSIKWYKDALLLPDNHRQ 611
Query: 310 TVYKNFEKTLQIIHVSEA-DSGNYQC-IAKNALGAIHHTISVRVKAAPYWITAPQNLVLS 367
V++N TL++ V + D G Y C + +I ++ V VK P Q
Sbjct: 612 VVFEN--GTLKLTDVQKGMDEGEYLCSVLIQPQLSISQSVHVAVKVPPLI----QPFEFP 665
Query: 368 PGEDGTLI---CRANGNPKP-RISWLTNG-VPIEIAPDDPSRKIDGDTIIFSNVQERSSA 422
P G L+ C + P RI+W +G V I + K ++ S+V + +
Sbjct: 666 PASIGQLLYIPCVVSSGDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNG 725
Query: 423 VYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEW 482
Y C ASN + + V P ++ P N I + +L+C+ G P P + W
Sbjct: 726 NYTCIASNAAATVSRERQLIVRVPPRFVVQPNNQ--DGIYGKAGVLNCSVDGYPPPKVMW 783
Query: 483 FKGAKGSALHEDIYVLHENGTLEI---------PVAQKDSTGTYTCVARNKLGM-AKNEV 532
K AKGS + + + G ++I V ++D G Y C A N +G +
Sbjct: 784 -KHAKGSGNPQQYHPVPLTGRIQILPNSSLLIRHVLEED-IGYYLCQASNGVGTDISKSM 841
Query: 533 HLEIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDE--RFTV 590
L +K P I P + +G C + + + + W K + + D R+ +
Sbjct: 842 FLTVKIPAMITSHPNTTIAIKGHAKELNCTARGERPI--IIRWEKGDTVIDPDRVMRYAI 899
Query: 591 -DKDH-------LVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVDVPNPPFDLELTDQ 642
KD+ L + DS ++C A + L+V + P+PP +LE+ +
Sbjct: 900 ATKDNGDEVVSTLKLKPADRGDSVFFSCHAINSYGEDRGLIQLTVQEPPDPP-ELEIREV 958
Query: 643 LDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQL-KLSPYVNY 701
+S+ L WT D NS IT F IEY++ +S T A + L P Y
Sbjct: 959 KARSMNLRWTQRFDGNSIITGFDIEYKNKSDSWDFKQSTRNISPTINQANIVDLHPASVY 1018
Query: 702 SFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNG 761
S R+ + N IG+S PS+ T+ + PD P V ++ +TWK NG
Sbjct: 1019 SIRMYSFNKIGRSEPSKELT-ISTEEAAPDGPPMDVTLQPVTSQSIQVTWKAPKKELQNG 1077
Query: 762 PGLQYKVSWRQKD-GDDEWTSVV----VANVSKYIVSGTPTFVPYLIKVQALNDMGFAPE 816
Y++ +R+ G + S+V + Y + F Y + VQA N G P
Sbjct: 1078 VIRGYQIGYRENSPGSNGQYSIVEMKATGDSEVYTLDNLKKFAQYGVVVQAFNRAGTGPS 1137
Query: 817 PAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSS 876
+ + + ED+P P NVR + S +A + W P ++ G L+GYR+ +W
Sbjct: 1138 SSEINATTLEDVPSQPPENVRALSITSDVAVISWSEPPRSTLNGVLKGYRVIFWSLYVDG 1197
Query: 877 KRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVP 936
+ E + +T + L G+E F++Y++ V G+G S T E VP
Sbjct: 1198 EWG----EMQNITTTRERVE--LRGMEKFTNYSVQVLAYTQAGDGVRSSVLYIQTKEDVP 1251
Query: 937 SAPSSLKIVNPTLDSLTLEWDPPSHPNGILTEYTL------KYQPINSTHELGPLVDLKI 990
P+ +K V + S+ + W PP+ PNG++ +YT+ QP S +E P
Sbjct: 1252 GPPAGIKAVPSSASSVVVSWLPPTKPNGVIRKYTIFCSSPGSGQPAPSEYETSP------ 1305
Query: 991 PANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEEAVTTVDEAMA 1037
+ + + +LN +Y + A TSAG G+ + + +A A
Sbjct: 1306 --EQLFYRIAHLNRGQQYLLWVAAVTSAGRGNSSEKVTIEPAGKAPA 1350
Score = 122 bits (306), Expect = 2e-27
Identities = 142/569 (24%), Positives = 222/569 (39%), Gaps = 52/569 (9%)
Query: 58 IVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETY--EGVY 115
+V+ C A G P + W T DI P + GTL + S ++ + Y
Sbjct: 103 VVVPCPAAGSPSAALRWYL-ATGDDIYDVPHIRHVHANGTLQLYPFSPSAFNSFIHDNDY 161
Query: 116 QCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPP--PIIF 173
CTA N G S NI V+ +T ++E G V C P + ++
Sbjct: 162 FCTAENAAGKIRSPNIRVKAVFREPYTV-RVEDQRSMRGNVAVFKCLIPSSVQEYVSVVS 220
Query: 174 WMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVI 233
W ++ +P+ R +G LY S+V ED Y C + ++ +Q
Sbjct: 221 WEKDTVSIIPE-HRFFITYHGGLYISDVQKEDALSTYRCITKHKYSGETRQSN------- 272
Query: 234 SVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPT 293
A LS T+ E PT L ++E G+ + L C A G P
Sbjct: 273 ---------GARLSVTD------PAESIPTILD---GFHSQEVWAGHTVELPCTASGYPI 314
Query: 294 PIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKA 353
P I W K+ LP + K L I + DSG Y C N G+ T + V
Sbjct: 315 PAIRWLKDGRPLPADSRWTKRITG-LTISDLRTEDSGTYICEVTNTFGSAEATGILMVID 373
Query: 354 APYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDD--PSRKIDGDTI 411
+ P+ L G L C G+P+ I W N + PD+ R + +T+
Sbjct: 374 PLHVTLTPKKLKTGIGSTVILSCALTGSPEFTIRWYRN--TELVLPDEAISIRGLSNETL 431
Query: 412 IFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIANRPALLDCA 471
+ ++ Q+ S YQC A+ + A + + PRI++ + V L CA
Sbjct: 432 LITSAQKSHSGAYQCFATRKAQTAQDFAIIALEDGTPRIVSSFSEKV-VNPGEQFSLMCA 490
Query: 472 FFGSPLPTIEWFKG----AKGSALHEDIYVLHENGT---LEIPVAQKDSTGTYTCVARNK 524
G+P PT+ W + + + Y + + T + + Q G Y C ARN
Sbjct: 491 AKGAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNL 550
Query: 525 LGMAKNEVHLEIKDPTWI-VKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELP 583
+G A+ + + ++ P I + AV R ++++ C+V S + W KD LP
Sbjct: 551 VGSAEYQARINVRGPPSIRAMRNITAVAGRDTLIN--CRVIGYPYYS--IKWYKDALLLP 606
Query: 584 SDERFTV-DKDHLVVADVSDD-DSGTYTC 610
+ R V + L + DV D G Y C
Sbjct: 607 DNHRQVVFENGTLKLTDVQKGMDEGEYLC 635
Score = 67.4 bits (163), Expect = 8e-11
Identities = 69/308 (22%), Positives = 115/308 (37%), Gaps = 22/308 (7%)
Query: 340 LGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLI-CRANGNPKPRISW-LTNGVPIEI 397
L ++H V + Y++ V G ++ C A G+P + W L G I
Sbjct: 70 LDSLHKARPEDVGTSLYFVNDSLQQVTFSSSVGVVVPCPAAGSPSAALRWYLATGDDIYD 129
Query: 398 APDDPSRKIDGDTIIFSNVQERSSAV-----YQCNASNEYGYLLA-NAFVNVLAEPPRIL 451
P +G ++ ++ Y C A N G + + N V + P +
Sbjct: 130 VPHIRHVHANGTLQLYPFSPSAFNSFIHDNDYFCTAENAAGKIRSPNIRVKAVFREPYTV 189
Query: 452 TPANTLYQVIANRPALLDCAFFGSP---LPTIEWFKGAKGSALHEDIYVLHENGTLEIPV 508
+ + + A+ C S + + W K ++ + G V
Sbjct: 190 RVEDQ--RSMRGNVAVFKCLIPSSVQEYVSVVSWEKDTVSIIPEHRFFITYHGGLYISDV 247
Query: 509 AQKDSTGTYTCVARNKLG---MAKNEVHLEIKDPT----WIVKQPEYAVVQRGSMVSFEC 561
++D+ TY C+ ++K N L + DP I+ V G V C
Sbjct: 248 QKEDALSTYRCITKHKYSGETRQSNGARLSVTDPAESIPTILDGFHSQEVWAGHTVELPC 307
Query: 562 KVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVADVSDDDSGTYTCVANTTLDSVSA 621
++ WLKD R LP+D R+T L ++D+ +DSGTY C T S A
Sbjct: 308 TASGYPIPAIR--WLKDGRPLPADSRWTKRITGLTISDLRTEDSGTYICEVTNTFGSAEA 365
Query: 622 SAVLSVVD 629
+ +L V+D
Sbjct: 366 TGILMVID 373
Score = 50.1 bits (118), Expect = 1e-05
Identities = 60/272 (22%), Positives = 107/272 (39%), Gaps = 49/272 (18%)
Query: 468 LDCAFFGSPLPTIEWFKGAKGSALHEDI---YVLHENGTLEIPVAQKDSTGTYTCVARNK 524
L C G P P ++W K ++ SA+ + ++H NGTL + + + +G YTC A N
Sbjct: 1369 LPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTNGTLLLRAVKAEDSGYYTCTATNT 1428
Query: 525 LGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPS 584
G V+L ++ P QP V + + S+T+ W+ + S
Sbjct: 1429 GGFDTIIVNLLVQVPP---DQPRLTVSKTSAS-------------SITLTWIPGDNGGSS 1472
Query: 585 DERFTVD---------KDHLVVAD-----VSDDDSGTYTCVANTTLDSVSASAVLSVVDV 630
F + KD + + + GT+ V +SV + + +++
Sbjct: 1473 IRGFVLQYSVDNSEEWKDVFISSSERSFKLDSLKCGTWYKVKLAAKNSVGSGRISEIIEA 1532
Query: 631 ------PNPPFDLELTDQLDKS-VQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQ-- 681
P+ D L ++ + +L+ ++ PIT ++EY G W Q
Sbjct: 1533 KTHGREPSFSKDQHLFTHINSTHARLNLQGWNNGGCPITAIVLEY----RPKGTWAWQGL 1588
Query: 682 -TEVSGTQTTAQLKLSPYVNYSFRVMAVNSIG 712
SG +L+ + + Y R+ A NS G
Sbjct: 1589 RANSSGEVFLTELREATW--YELRMRACNSAG 1618
Score = 45.8 bits (107), Expect = 2e-04
Identities = 91/456 (19%), Positives = 165/456 (36%), Gaps = 51/456 (11%)
Query: 629 DVPN-PPFDLELTDQLDKSVQLSWT--PGDDNNSPITKFIIEYEDAMHKPGLWHHQTEVS 685
DVP+ PP ++ +SW+ P N + + + + +++ G W ++
Sbjct: 1148 DVPSQPPENVRALSITSDVAVISWSEPPRSTLNGVLKGYRVIFW-SLYVDGEWGEMQNIT 1206
Query: 686 GTQTTAQLK-LSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEP 744
T+ +L+ + + NYS +V+A G + S S Y+ + P ++ + S
Sbjct: 1207 TTRERVELRGMEKFTNYSVQVLAYTQAGDGVRS--SVLYIQTKEDVPGPPAGIKAVPSSA 1264
Query: 745 DNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDEWTSVVVANVSK--YIVSGTPTFVPYL 802
++V++W P + NG +Y + S + + Y ++ YL
Sbjct: 1265 SSVVVSWLPPT--KPNGVIRKYTIFCSSPGSGQPAPSEYETSPEQLFYRIAHLNRGQQYL 1322
Query: 803 IKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVN--STLAEVHWDPV--PLKSI 858
+ V A+ G G+S E + + G +++ T+ V P S+
Sbjct: 1323 LWVAAVTSAG--------RGNSSEKVTIEPAGKAPAKIISFGGTVTTPWMKDVRLPCNSV 1374
Query: 859 RGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGK 918
+ W S ++ L E +YT G
Sbjct: 1375 GDPAPAVK---WTKDSEDSAIPVSMDGHRLIHTNGTLLLRAVKAEDSGYYTCTATNTGG- 1430
Query: 919 GEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDPPSHPNGILTEYTLKYQPINS 978
+ N VP L + + S+TL W P + + + L+Y NS
Sbjct: 1431 -----FDTIIVNLLVQVPPDQPRLTVSKTSASSITLTWIPGDNGGSSIRGFVLQYSVDNS 1485
Query: 979 THELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITE--EAVTTVDEAM 1036
D+ I +++ + L +L T YK A+ S GSG +I+E EA T E
Sbjct: 1486 EE----WKDVFISSSERSFKLDSLKCGTWYKVKLAAKNSVGSG-RISEIIEAKTHGREPS 1540
Query: 1037 ASRQVDIAT-----------QGWFIGLMCAVALLIL 1061
S+ + T QGW G C + ++L
Sbjct: 1541 FSKDQHLFTHINSTHARLNLQGWNNG-GCPITAIVL 1575
Score = 36.6 bits (83), Expect = 0.15
Identities = 22/85 (25%), Positives = 38/85 (44%), Gaps = 4/85 (4%)
Query: 370 EDGTLICRANGNPKPRISWL--TNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCN 427
+D L C + G+P P + W + I ++ D T++ V+ S Y C
Sbjct: 1365 KDVRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTNGTLLLRAVKAEDSGYYTCT 1424
Query: 428 ASNEYGY--LLANAFVNVLAEPPRI 450
A+N G+ ++ N V V + PR+
Sbjct: 1425 ATNTGGFDTIIVNLLVQVPPDQPRL 1449
Score = 34.3 bits (77), Expect = 0.72
Identities = 25/78 (32%), Positives = 36/78 (46%), Gaps = 8/78 (10%)
Query: 284 LECIAEGLPTPIIYWAK--EDGMLPKN----RTVYKNFEKTLQIIHVSEADSGNYQCIAK 337
L C + G P P + W K ED +P + R ++ N TL + V DSG Y C A
Sbjct: 1369 LPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTN--GTLLLRAVKAEDSGYYTCTAT 1426
Query: 338 NALGAIHHTISVRVKAAP 355
N G +++ V+ P
Sbjct: 1427 NTGGFDTIIVNLLVQVPP 1444
Score = 32.0 bits (71), Expect = 3.6
Identities = 27/96 (28%), Positives = 42/96 (43%), Gaps = 13/96 (13%)
Query: 56 ENIVIQCEAKGKPPPSFSWTRNGTH----FDIDKDPLVTMKPGTGTLIINIMSEGKAETY 111
+++ + C + G P P+ WT++ +D L+ GTL++ + KAE
Sbjct: 1365 KDVRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHT---NGTLLLRAV---KAED- 1417
Query: 112 EGVYQCTARNERG--AAVSNNIVVRPSRSPLWTKEK 145
G Y CTA N G + N +V P P T K
Sbjct: 1418 SGYYTCTATNTGGFDTIIVNLLVQVPPDQPRLTVSK 1453
>gi|157311649 neogenin homolog 1 [Homo sapiens]
Length = 1461
Score = 226 bits (576), Expect = 1e-58
Identities = 216/801 (26%), Positives = 343/801 (42%), Gaps = 85/801 (10%)
Query: 277 LRGNVLSLECIAEGLPTPIIYWAKEDG------------MLPKNRTVYKNFEKTLQIIHV 324
+RG+ + L C A P+P I W K+DG +LP N ++H
Sbjct: 65 VRGSSVILNCSAYSEPSPKIEW-KKDGTFLNLVSDDRRQLLPDGSLFISN------VVHS 117
Query: 325 --SEADSGNYQCIAK-NALGAI-HHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANG 380
++ D G YQC+A +LG I T + V P + + P+ + G + L C N
Sbjct: 118 KHNKPDEGYYQCVATVESLGTIISRTAKLIVAGLPRFTSQPEPSSVYAGNNAILNCEVNA 177
Query: 381 NPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAF 440
+ P + W N P+ + DD K+ ++ SN E +Y+C + ++
Sbjct: 178 DLVPFVRWEQNRQPLLL--DDRVIKLPSGMLVISNATEGDGGLYRCVVESGGPPKYSDEV 235
Query: 441 -VNVLAEPPRI-----LTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKG-SALHE 493
+ VL +P I L + L +VI + +L C G P PTI+W K +
Sbjct: 236 ELKVLPDPEVISDLVFLKQPSPLVRVIG-QDVVLPCVASGLPTPTIKWMKNEEALDTESS 294
Query: 494 DIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQR 553
+ VL G+LEI +D GTY C+A N + + L ++ +KQP
Sbjct: 295 ERLVLLAGGSLEISDVTEDDAGTYFCIADNGNETIEAQAELTVQAQPEFLKQPTNIYAHE 354
Query: 554 GSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH-LVVADVSDDDSGTYTCVA 612
+ FEC+V T TV W+K+ + + F + K+H L V + D G Y C+A
Sbjct: 355 SMDIVFECEVTGKPTP--TVKWVKNGDMVIPSDYFKIVKEHNLQVLGLVKSDEGFYQCIA 412
Query: 613 NTTLDSVSASAVLSVVD--------VPNPPFDLELTDQLDKSVQLSW-TPGDDNNSPITK 663
+ + A A L +++ +P+ P D+ + + ++L+W TP D +
Sbjct: 413 ENDVGNAQAGAQLIILEHAPATTGPLPSAPRDVVASLVSTRFIKLTWRTPASDPHGDNLT 472
Query: 664 FIIEYEDAMHKPGLWHHQTEVSG----TQTTAQLKLSPYVNYSFRVMAVNSIGK---SLP 716
+ + Y K G+ + E + Q T Q L P Y FRVMA N G S P
Sbjct: 473 YSVFYT----KEGIARERVENTSHPGEMQVTIQ-NLMPATVYIFRVMAQNKHGSGESSAP 527
Query: 717 SEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWK-PLNGFESNGPGLQYKVSWRQKDG 775
Q + P N + + P ++ +TW+ P++G NG YK+ + +K G
Sbjct: 528 LRVETQPEVQLPGPAPN---LRAYAASPTSITVTWETPVSG---NGEIQNYKLYYMEK-G 580
Query: 776 DDEWTSVVVANVSKYIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGN 835
D+ V V++ S Y ++G + Y +V A N G V + D+P AP N
Sbjct: 581 TDKEQDVDVSSHS-YTINGLKKYTEYSFRVVAYNKHGPGVSTPDVAVRTLSDVPSAAPQN 639
Query: 836 VRVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKT 895
+ + V NS +HW P + G + GY+I Y K S + G++
Sbjct: 640 LSLEVRNSKSIMIHWQPPAPATQNGQITGYKIRYRKASRKSDVTETLVS-------GTQL 692
Query: 896 HGMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEG------VPSAPSSLKIVNPTL 949
++ GL+ + Y V + G GPA+ T E VP PSSL V P +
Sbjct: 693 SQLIEGLDRGTEYNFRVAALTINGTGPATDWLSAETFESDLDETRVPEVPSSLH-VRPLV 751
Query: 950 DSLTLEWDPPSHPNGILTEYTLKYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRYK 1009
S+ + W PP + N ++ Y + Y I S H VD K + +T++NL+ S+ Y
Sbjct: 752 TSIVVSWTPPENQNIVVRGYAIGY-GIGSPHAQTIKVDYK----QRYYTIENLDPSSHYV 806
Query: 1010 FYFYAQTSAGSGSQITEEAVT 1030
A + G G + E AVT
Sbjct: 807 ITLKAFNNVGEGIPLYESAVT 827
Score = 171 bits (434), Expect = 3e-42
Identities = 241/1058 (22%), Positives = 398/1058 (37%), Gaps = 158/1058 (14%)
Query: 47 PKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEG 106
P D + ++++ C A +P P W ++GT ++ D + P I N++
Sbjct: 59 PVDTLSVRGSSVILNCSAYSEPSPKIEWKKDGTFLNLVSDDRRQLLPDGSLFISNVVHSK 118
Query: 107 KAETYEGVYQCTARNER-GAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPI 165
+ EG YQC A E G +S + + P +T + EP ++ +G + +L C
Sbjct: 119 HNKPDEGYYQCVATVESLGTIISRTAKLIVAGLPRFTSQP-EPSSVYAGNNAILNCEVNA 177
Query: 166 GLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQK 225
L P + W N Q L +RV + +G L SN D Y C +
Sbjct: 178 DLVP-FVRWEQNR-QPLLLDDRVIKLPSGMLVISNATEGDGGL-YRCVVESGGPPKYSDE 234
Query: 226 QPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEELRGNVLSLE 285
+ +KV+ E+ +SD F S R + G + L
Sbjct: 235 --VELKVLPDPEV-------ISDLVFLKQPSPLVR----------------VIGQDVVLP 269
Query: 286 CIAEGLPTPIIYWAKEDGMLP--KNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGAI 343
C+A GLPTP I W K + L + + +L+I V+E D+G Y CIA N I
Sbjct: 270 CVASGLPTPTIKWMKNEEALDTESSERLVLLAGGSLEISDVTEDDAGTYFCIADNGNETI 329
Query: 344 HHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPS 403
+ V+A P ++ P N+ D C G P P + W+ NG + P D
Sbjct: 330 EAQAELTVQAQPEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMV--IPSDYF 387
Query: 404 RKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIAN 463
+ + + + + YQC A N+ G A A + +L P P + +
Sbjct: 388 KIVKEHNLQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEHAPATTGP-------LPS 440
Query: 464 RPALLDCAFFGSPLPTIEWFKGAK---GSALHEDIYVLHEN------------GTLEIPV 508
P + + + + W A G L ++ E G +++ +
Sbjct: 441 APRDVVASLVSTRFIKLTWRTPASDPHGDNLTYSVFYTKEGIARERVENTSHPGEMQVTI 500
Query: 509 AQKDSTGTYT--CVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFECKVKHD 566
Y +A+NK G ++ L ++ V+ P A R S
Sbjct: 501 QNLMPATVYIFRVMAQNKHGSGESSAPLRVETQPE-VQLPGPAPNLRAYAAS-------- 551
Query: 567 HTLSLTVLW---LKDNRELPSDERFTVDKDHLVVADVSDDDSGTYTC------------- 610
S+TV W + N E+ + + + ++K DV D S +YT
Sbjct: 552 -PTSITVTWETPVSGNGEIQNYKLYYMEKGTDKEQDV-DVSSHSYTINGLKKYTEYSFRV 609
Query: 611 -VANTTLDSVSAS--AVLSVVDVPNP-PFDLELTDQLDKSVQLSWTPGDD--NNSPITKF 664
N VS AV ++ DVP+ P +L L + KS+ + W P N IT +
Sbjct: 610 VAYNKHGPGVSTPDVAVRTLSDVPSAAPQNLSLEVRNSKSIMIHWQPPAPATQNGQITGY 669
Query: 665 IIEYEDAMHKPGLWHHQTEVSGTQTTAQLK-LSPYVNYSFRVMA--VNSIGKSLPSEASE 721
I Y A K + +T VSGTQ + ++ L Y+FRV A +N G + ++E
Sbjct: 670 KIRYRKASRKSDVT--ETLVSGTQLSQLIEGLDRGTEYNFRVAALTINGTGPATDWLSAE 727
Query: 722 QYLTKASEPDKNPTAVEGLGSEP--DNLVITWKPLN-----------GFESNGPGLQ-YK 767
+ + E + P L P ++V++W P G+ P Q K
Sbjct: 728 TFESDLDET-RVPEVPSSLHVRPLVTSIVVSWTPPENQNIVVRGYAIGYGIGSPHAQTIK 786
Query: 768 VSWRQKDGDDEWTSVVVANVSKYIVSGTPTFVPYLIKVQALNDMGFAP---EPAVVMGHS 824
V ++Q+ Y + Y+I ++A N++G E AV H+
Sbjct: 787 VDYKQR---------------YYTIENLDPSSHYVITLKAFNNVGEGIPLYESAVTRPHT 831
Query: 825 G-----------------EDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIRGHLQG-YR 866
+ PM+ P V+ ++++ + W L + Y
Sbjct: 832 DTSEVDLFVINAPYTPVPDPTPMMPPVGVQASILSHDTIRITWADNSLPKHQKITDSRYY 891
Query: 867 IYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASPD 926
WKT + ++ L++ ++ GL+P + Y +V V G+ S
Sbjct: 892 TVRWKTNIPANTKYKNANATTLSY-------LVTGLKPNTLYEFSVMVTKGRRSSTWSMT 944
Query: 927 RVFNTPEGVP-SAPSSLKIVNPTLDSLTL--EWDPPSHPNGILTEYTLKYQPINSTHELG 983
T E VP S P + +V+ T+ W PPS NG +T Y + Y + E+
Sbjct: 945 AHGTTFELVPTSPPKDVTVVSKEGKPKTIIVNWQPPSEANGKITGYII-YYSTDVNAEIH 1003
Query: 984 PLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSG 1021
V + N+ ++ L T Y F A+ S G G
Sbjct: 1004 DWVIEPVVGNRLTHQIQELTLDTPYYFKIQARNSKGMG 1041
Score = 132 bits (331), Expect = 3e-30
Identities = 165/722 (22%), Positives = 288/722 (39%), Gaps = 97/722 (13%)
Query: 348 SVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKID 407
S+R Y++ P + + G L C A P P+I W +G + + DD + +
Sbjct: 46 SIRTFTPFYFLVEPVDTLSVRGSSVILNCSAYSEPSPKIEWKKDGTFLNLVSDDRRQLLP 105
Query: 408 GDTIIFSNV-----QERSSAVYQCNASNE-YGYLLANAFVNVLAEPPRILTPANTLYQVI 461
++ SNV + YQC A+ E G +++ ++A PR T V
Sbjct: 106 DGSLFISNVVHSKHNKPDEGYYQCVATVESLGTIISRTAKLIVAGLPR-FTSQPEPSSVY 164
Query: 462 ANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVA 521
A A+L+C +P + W + + L + + L +G L I A + G Y CV
Sbjct: 165 AGNNAILNCEVNADLVPFVRWEQNRQPLLLDDRVIKL-PSGMLVISNATEGDGGLYRCVV 223
Query: 522 RNKLGMAKNEVHLEIK---DPTWI-----VKQPEYAVVQRGSMVSFECKVKHDHTLSLTV 573
+ G K +E+K DP I +KQP V G V C T T+
Sbjct: 224 ESG-GPPKYSDEVELKVLPDPEVISDLVFLKQPSPLVRVIGQDVVLPCVASGLPT--PTI 280
Query: 574 LWLKDNREL--PSDERFT-VDKDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVDV 630
W+K+ L S ER + L ++DV++DD+GTY C+A+ +++ A A L+V
Sbjct: 281 KWMKNEEALDTESSERLVLLAGGSLEISDVTEDDAGTYFCIADNGNETIEAQAELTVQAQ 340
Query: 631 P---------------NPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKP 675
P + F+ E+T + +V+ W D P F I E
Sbjct: 341 PEFLKQPTNIYAHESMDIVFECEVTGKPTPTVK--WVKNGDMVIPSDYFKIVKE------ 392
Query: 676 GLWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPT 735
H +V G + + ++ +A N +G ++A Q + + P
Sbjct: 393 ----HNLQVLGLVKSDE--------GFYQCIAENDVGN---AQAGAQLIIL----EHAPA 433
Query: 736 AVEGLGSEPDNLV----------ITWKPLNGFESNGPGLQYKVSWRQKD-GDDEWTSVVV 784
L S P ++V +TW+ + +G L Y V + ++ + +
Sbjct: 434 TTGPLPSAPRDVVASLVSTRFIKLTWR-TPASDPHGDNLTYSVFYTKEGIARERVENTSH 492
Query: 785 ANVSKYIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPG-NVRVNVVNS 843
+ + Y+ +V A N G A + + ++ + P N+R +
Sbjct: 493 PGEMQVTIQNLMPATVYIFRVMAQNKHGSGESSAPLRVETQPEVQLPGPAPNLRAYAASP 552
Query: 844 TLAEVHWD-PVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGL 902
T V W+ PV S G +Q Y++YY + + +++ S + GL
Sbjct: 553 TSITVTWETPV---SGNGEIQNYKLYYMEKGTDKEQD----------VDVSSHSYTINGL 599
Query: 903 EPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPS-APSSLKIVNPTLDSLTLEWDP--P 959
+ ++ Y+ V N G G ++PD T VPS AP +L + S+ + W P P
Sbjct: 600 KKYTEYSFRVVAYNKHGPGVSTPDVAVRTLSDVPSAAPQNLSLEVRNSKSIMIHWQPPAP 659
Query: 960 SHPNGILTEYTLKYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAG 1019
+ NG +T Y ++Y+ + + + + + + ++ L+ T Y F A T G
Sbjct: 660 ATQNGQITGYKIRYRKASRKSD---VTETLVSGTQLSQLIEGLDRGTEYNFRVAALTING 716
Query: 1020 SG 1021
+G
Sbjct: 717 TG 718
Score = 102 bits (253), Expect = 3e-21
Identities = 218/994 (21%), Positives = 361/994 (36%), Gaps = 170/994 (17%)
Query: 40 PTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLI 99
P T Q P+ + N ++ CE P W +N +D +K +G L+
Sbjct: 152 PRFTSQ-PEPSSVYAGNNAILNCEVNADLVPFVRWEQNRQPLLLDDR---VIKLPSGMLV 207
Query: 100 INIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSP-----LWTKEKLEPITLQSG 154
I+ +EG G+Y+C + S+ + ++ P L ++ P+ G
Sbjct: 208 ISNATEGDG----GLYRCVVESGGPPKYSDEVELKVLPDPEVISDLVFLKQPSPLVRVIG 263
Query: 155 QSLVLPCRPPIGLPPPIIFWMDNSFQR-LPQSERVSQGLNGDLYFSNVLPEDTREDYICY 213
Q +VLPC GLP P I WM N SER+ G L S+V ED Y C
Sbjct: 264 QDVVLPCVAS-GLPTPTIKWMKNEEALDTESSERLVLLAGGSLEISDVT-EDDAGTYFCI 321
Query: 214 ARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASN 273
A D N+TI A A+ + + P FL N
Sbjct: 322 A---------------------DNGNETIEAQ--------AELTVQAQPEFLKQPTNIYA 352
Query: 274 KEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQ 333
E + + EC G PTP + W K M+ + E LQ++ + ++D G YQ
Sbjct: 353 HESMD---IVFECEVTGKPTPTVKWVKNGDMVIPSDYFKIVKEHNLQVLGLVKSDEGFYQ 409
Query: 334 CIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGV 393
CIA+N +G + + L +P G L P+ ++ L +
Sbjct: 410 CIAENDVGNAQAGAQLII------------LEHAPATTGPL----PSAPRDVVASLVSTR 453
Query: 394 PIEIAPDDPSRKIDGDTIIFS---------------------------NVQERSSAVYQC 426
I++ P+ GD + +S N+ + +++
Sbjct: 454 FIKLTWRTPASDPHGDNLTYSVFYTKEGIARERVENTSHPGEMQVTIQNLMPATVYIFRV 513
Query: 427 NASNEYGYLLANAFVNVLAEPP-RILTPANTLYQVIANRPALL---DCAFFGS-PLPTIE 481
A N++G ++A + V +P ++ PA L A+ ++ + G+ + +
Sbjct: 514 MAQNKHGSGESSAPLRVETQPEVQLPGPAPNLRAYAASPTSITVTWETPVSGNGEIQNYK 573
Query: 482 WFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLG--------------- 526
+ KG+ +D+ V + T+ +K + ++ VA NK G
Sbjct: 574 LYYMEKGTDKEQDVDVSSHSYTIN--GLKKYTEYSFRVVAYNKHGPGVSTPDVAVRTLSD 631
Query: 527 ---MAKNEVHLEIKDPTWIVK--QPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRE 581
A + LE+++ I+ QP Q G + ++ + + S L +
Sbjct: 632 VPSAAPQNLSLEVRNSKSIMIHWQPPAPATQNGQITGYKIRYRKASRKSDVTETLVSGTQ 691
Query: 582 LPSDERFTVDKD---HLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVD---VPNPPF 635
L S +D+ + VA ++ + +G T D +SA S +D VP P
Sbjct: 692 L-SQLIEGLDRGTEYNFRVAALTINGTGPAT-------DWLSAETFESDLDETRVPEVPS 743
Query: 636 DLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQT-EVSGTQTTAQLK 694
L + L S+ +SWTP ++ N + + I Y G H QT +V Q ++
Sbjct: 744 SLHVRP-LVTSIVVSWTPPENQNIVVRGYAIGYGI-----GSPHAQTIKVDYKQRYYTIE 797
Query: 695 -LSPYVNYSFRVMAVNSIGKSLP--SEASEQYLTKASEPD-----------------KNP 734
L P +Y + A N++G+ +P A + T SE D P
Sbjct: 798 NLDPSSHYVITLKAFNNVGEGIPLYESAVTRPHTDTSEVDLFVINAPYTPVPDPTPMMPP 857
Query: 735 TAVEGLGSEPDNLVITW--KPLNGFESNGPGLQYKVSWRQKDGDDEWTSVVVANVSKYIV 792
V+ D + ITW L + Y V W+ + A Y+V
Sbjct: 858 VGVQASILSHDTIRITWADNSLPKHQKITDSRYYTVRWKTNIPANTKYKNANATTLSYLV 917
Query: 793 SGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDP 852
+G Y V + G + E +P P +V V + +
Sbjct: 918 TGLKPNTLYEFSVMVTKGRRSSTWSMTAHGTTFELVPTSPPKDVTVVSKEGKPKTIIVNW 977
Query: 853 VPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNV 912
P G + GY IYY S+ N + I G++ + L + Y +
Sbjct: 978 QPPSEANGKITGYIIYY-----STDVNAEIHDWVIEPVVGNRLTHQIQELTLDTPYYFKI 1032
Query: 913 RVVNGKGEGPASPDRVFNTPEGVPSAPSSLKIVN 946
+ N KG GP S F TP+ A SS K+ N
Sbjct: 1033 QARNSKGMGPMSEAVQFRTPK----ADSSDKMPN 1062
Score = 77.8 bits (190), Expect = 6e-14
Identities = 148/637 (23%), Positives = 246/637 (38%), Gaps = 89/637 (13%)
Query: 450 ILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFK-GAKGSALHEDIYVLHENGTLEIPV 508
++ P +TL + +L+C+ + P P IEW K G + + +D L +G+L I
Sbjct: 56 LVEPVDTLS--VRGSSVILNCSAYSEPSPKIEWKKDGTFLNLVSDDRRQLLPDGSLFISN 113
Query: 509 A-----QKDSTGTYTCVAR-NKLG-MAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFEC 561
K G Y CVA LG + L + QPE + V G+ C
Sbjct: 114 VVHSKHNKPDEGYYQCVATVESLGTIISRTAKLIVAGLPRFTSQPEPSSVYAGNNAILNC 173
Query: 562 KVKHDHTLSLTVLWLKDNRELPSDER-FTVDKDHLVVADVSDDDSGTYTCVANTT-LDSV 619
+V D L V W ++ + L D+R + LV+++ ++ D G Y CV +
Sbjct: 174 EVNAD--LVPFVRWEQNRQPLLLDDRVIKLPSGMLVISNATEGDGGLYRCVVESGGPPKY 231
Query: 620 SASAVLSVVDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGL-W 678
S L V+ P DL Q V++ G D P + P + W
Sbjct: 232 SDEVELKVLPDPEVISDLVFLKQPSPLVRVI---GQDVVLPCVA------SGLPTPTIKW 282
Query: 679 HHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSL-------PSEASEQYLTKASEPD 731
E T+++ +L L + + + G + ++ LT ++P+
Sbjct: 283 MKNEEALDTESSERLVLLAGGSLEISDVTEDDAGTYFCIADNGNETIEAQAELTVQAQPE 342
Query: 732 --KNPTAVEGLGSEPDNLV----ITWKPLNGFESNGPGLQYKVSWRQKDGDDEWTSVVVA 785
K PT + E ++V +T KP V W K+GD +V+
Sbjct: 343 FLKQPTNI--YAHESMDIVFECEVTGKPTP-----------TVKW-VKNGD-----MVIP 383
Query: 786 NVSKYIVSGTPTFVPYLIKVQ-------ALNDMGFAPEPA--VVMGHSGED---LPMVAP 833
+ IV V L+K A ND+G A A +++ H+ LP AP
Sbjct: 384 SDYFKIVKEHNLQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEHAPATTGPLPS-AP 442
Query: 834 GNVRVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKR--NRRHIEKKILTFQ 891
+V ++V++ ++ W P G Y ++Y K + +R N H + +T Q
Sbjct: 443 RDVVASLVSTRFIKLTWR-TPASDPHGDNLTYSVFYTKEGIARERVENTSHPGEMQVTIQ 501
Query: 892 GSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPAS-PDRVFNTPE-GVPSAPSSLKIVNPTL 949
L P + Y V N G G +S P RV PE +P +L+ +
Sbjct: 502 N---------LMPATVYIFRVMAQNKHGSGESSAPLRVETQPEVQLPGPAPNLRAYAASP 552
Query: 950 DSLTLEWDPPSHPNGILTEYTLKYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRYK 1009
S+T+ W+ P NG + Y L Y E G + + + +T+ L T Y
Sbjct: 553 TSITVTWETPVSGNGEIQNYKLYYM------EKGTDKEQDVDVSSHSYTINGLKKYTEYS 606
Query: 1010 FYFYAQTSAGSGSQITEEAVTTVDEAMASRQVDIATQ 1046
F A G G + AV T+ + ++ +++ +
Sbjct: 607 FRVVAYNKHGPGVSTPDVAVRTLSDVPSAAPQNLSLE 643
Score = 42.4 bits (98), Expect = 0.003
Identities = 40/153 (26%), Positives = 63/153 (41%), Gaps = 13/153 (8%)
Query: 31 EVPLDLVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVT 90
EV DLV + Q SP +I +++V+ C A G P P+ W +N D + +
Sbjct: 244 EVISDLV---FLKQPSPLVRVIG--QDVVLPCVASGLPTPTIKWMKNEEALDTESSERLV 298
Query: 91 MKPGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPIT 150
+ G G+L I+ ++E A G Y C A N + + P + K+ I
Sbjct: 299 LLAG-GSLEISDVTEDDA----GTYFCIADN-GNETIEAQAELTVQAQPEFLKQPTN-IY 351
Query: 151 LQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLP 183
+V C G P P + W+ N +P
Sbjct: 352 AHESMDIVFECE-VTGKPTPTVKWVKNGDMVIP 383
Score = 42.0 bits (97), Expect = 0.003
Identities = 41/139 (29%), Positives = 63/139 (45%), Gaps = 10/139 (7%)
Query: 632 NPPFDLELTDQ--LDKSVQLSWTPGDDNNSPITKFIIEYE-DAMHKPGLWHHQTEVSGTQ 688
+PP D+ + + K++ ++W P + N IT +II Y D + W + V
Sbjct: 956 SPPKDVTVVSKEGKPKTIIVNWQPPSEANGKITGYIIYYSTDVNAEIHDWVIEPVVGNRL 1015
Query: 689 TTAQLKLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNP----TAVEGLGSEP 744
T +L+ Y F++ A NS G SEA + KA DK P + G GS
Sbjct: 1016 THQIQELTLDTPYYFKIQARNSKGMGPMSEAVQFRTPKADSSDKMPNDQASGSGGKGSRL 1075
Query: 745 DNLVITWK-PLNGFESNGP 762
+L +K P++G SN P
Sbjct: 1076 PDLGSDYKPPMSG--SNSP 1092
>gi|110431348 deleted in colorectal carcinoma [Homo sapiens]
Length = 1447
Score = 213 bits (543), Expect = 7e-55
Identities = 210/797 (26%), Positives = 328/797 (41%), Gaps = 67/797 (8%)
Query: 272 SNKEELRGNVLSLECIAEG-LPTPIIYWAKED-----GMLPKNRTVYKNFEKTLQIIHVS 325
S+ +RG + L+C AE P+I W K+ GM + + + I+H
Sbjct: 47 SDAVTMRGGNVLLDCSAESDRGVPVIKWKKDGIHLALGMDERKQQLSNGSLLIQNILHSR 106
Query: 326 --EADSGNYQCIAK--NALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGN 381
+ D G YQC A ++ I T V V +++ +++ G+ L C G
Sbjct: 107 HHKPDEGLYQCEASLGDSGSIISRTAKVAVAGPLRFLSQTESVTAFMGDTVLLKCEVIGE 166
Query: 382 PKPRISWLTNGVPIEIAPDDPSRKI--DGDTIIFSNVQERSSAVYQCNASNEYGYLLAN- 438
P P I W N + P D SR + + S +Q +Y+C+A N N
Sbjct: 167 PMPTIHWQKNQQDLTPIPGD-SRVVVLPSGALQISRLQPGDIGIYRCSARNPASSRTGNE 225
Query: 439 AFVNVLAEPPR------ILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALH 492
A V +L++P + P+N + I + A+L+C G P P+ W +G + L
Sbjct: 226 AEVRILSDPGLHRQLYFLQRPSNVV--AIEGKDAVLECCVSGYPPPSFTWLRGEEVIQLR 283
Query: 493 EDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQ 552
Y L L I D +G YTCV K L + P W + P
Sbjct: 284 SKKYSLLGGSNLLISNVTDDDSGMYTCVVTYKNENISASAELTVLVPPWFLNHPSNLYAY 343
Query: 553 RGSMVSFECKVKHDHTLSLTVLWLKD-NRELPSDERFTVDKDHLVVADVSDDDSGTYTCV 611
+ FEC V TV W+K+ + +PSD V +L + V D G Y CV
Sbjct: 344 ESMDIEFECTVSGKPV--PTVNWMKNGDVVIPSDYFQIVGGSNLRILGVVKSDEGFYQCV 401
Query: 612 ANTTLDSVSASAVLSVVD--------VPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITK 663
A + SA L V +P+ P D+ + V+LSW P + I
Sbjct: 402 AENEAGNAQTSAQLIVPKPAIPSSSVLPSAPRDVVPVLVSSRFVRLSWRPPAEAKGNIQT 461
Query: 664 FIIEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEASEQY 723
F + + + T+ Q T L P Y+FRV+A N G P E+S Q
Sbjct: 462 FTVFFSREGDNRERALNTTQPGSLQLTVG-NLKPEAMYTFRVVAYNEWG---PGESS-QP 516
Query: 724 LTKASEPD-KNPTAVEGL---GSEPDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDEW 779
+ A++P+ + P VE L + P +++ITW+P +NGP Y++ + E
Sbjct: 517 IKVATQPELQVPGPVENLQAVSTSPTSILITWEP--PAYANGPVQGYRLFCTEVSTGKE- 573
Query: 780 TSVVVANVSKYIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVN 839
++ V +S Y + G F Y ++ A N G + + D+P P NV +
Sbjct: 574 QNIEVDGLS-YKLEGLKKFTEYSLRFLAYNRYGPGVSTDDITVVTLSDVPSAPPQNVSLE 632
Query: 840 VVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGML 899
VVNS +V W P P + G + GY+I + KT + T + + +
Sbjct: 633 VVNSRSIKVSWLPPPSGTQNGFITGYKIRHRKTTRRGEME---------TLEPNNLWYLF 683
Query: 900 PGLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEG------VPSAPSSLKIVNPTLDSLT 953
GLE S Y+ V + G GP S TPE VP PSSL V P + +
Sbjct: 684 TGLEKGSQYSFQVSAMTVNGTGPPSNWYTAETPENDLDESQVPDQPSSLH-VRPQTNCII 742
Query: 954 LEWDPPSHPNGILTEYTLKYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFY 1013
+ W PP +PN ++ Y + Y + E +++ + + ++++ L S+ Y
Sbjct: 743 MSWTPPLNPNIVVRGYIIGYGVGSPYAE-----TVRVDSKQRYYSIERLESSSHYVISLK 797
Query: 1014 AQTSAGSGSQITEEAVT 1030
A +AG G + E A T
Sbjct: 798 AFNNAGEGVPLYESATT 814
Score = 147 bits (370), Expect = 8e-35
Identities = 237/1066 (22%), Positives = 395/1066 (37%), Gaps = 171/1066 (16%)
Query: 47 PKDYIIDPRENIVIQCEAKG-KPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSE 105
P D + N+++ C A+ + P W ++G H + D LI NI+
Sbjct: 46 PSDAVTMRGGNVLLDCSAESDRGVPVIKWKKDGIHLALGMDERKQQLSNGSLLIQNILHS 105
Query: 106 GKAETYEGVYQCTAR-NERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPP 164
+ EG+YQC A + G+ +S V + PL + E +T G +++L C
Sbjct: 106 RHHKPDEGLYQCEASLGDSGSIISRTAKVAVA-GPLRFLSQTESVTAFMGDTVLLKCE-V 163
Query: 165 IGLPPPIIFWMDN--SFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTI 222
IG P P I W N +P RV +G L S + P D Y C AR
Sbjct: 164 IGEPMPTIHWQKNQQDLTPIPGDSRVVVLPSGALQISRLQPGDI-GIYRCSAR------- 215
Query: 223 QQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEELRGNVL 282
P S + N+ LSD + +RP SN + G
Sbjct: 216 ---NPASSRT-----GNEAEVRILSDPGLHRQLYFLQRP----------SNVVAIEGKDA 257
Query: 283 SLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNF-EKTLQIIHVSEADSGNYQCIAKNALG 341
LEC G P P W + + ++ Y L I +V++ DSG Y C+
Sbjct: 258 VLECCVSGYPPPSFTWLRGEEVIQLRSKKYSLLGGSNLLISNVTDDDSGMYTCVVTYKNE 317
Query: 342 AIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDD 401
I + + V P+++ P NL D C +G P P ++W+ NG + P D
Sbjct: 318 NISASAELTVLVPPWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMKNG--DVVIPSD 375
Query: 402 PSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVI 461
+ + G + V + YQC A NE G NA + P+ P+++ V+
Sbjct: 376 YFQIVGGSNLRILGVVKSDEGFYQCVAENEAG----NAQTSAQLIVPKPAIPSSS---VL 428
Query: 462 ANRPALLDCAFFGSPLPTIEWF--KGAKGSALHEDIYVLHEN------------GTLEIP 507
+ P + S + W AKG+ ++ E G+L++
Sbjct: 429 PSAPRDVVPVLVSSRFVRLSWRPPAEAKGNIQTFTVFFSREGDNRERALNTTQPGSLQLT 488
Query: 508 VA--QKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAV---VQRGSMVSFECK 562
V + ++ T+ VA N+ G E P + QPE V V+ VS
Sbjct: 489 VGNLKPEAMYTFRVVAYNEWGPG------ESSQPIKVATQPELQVPGPVENLQAVS---- 538
Query: 563 VKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVADVS-------DDDSGTYTCVANTT 615
S+ + W E P+ V L +VS + D +Y
Sbjct: 539 ---TSPTSILITW-----EPPAYANGPVQGYRLFCTEVSTGKEQNIEVDGLSYKLEGLKK 590
Query: 616 LDSVSAS----------------AVLSVVDVPN-PPFDLELTDQLDKSVQLSW--TPGDD 656
S V+++ DVP+ PP ++ L +S+++SW P
Sbjct: 591 FTEYSLRFLAYNRYGPGVSTDDITVVTLSDVPSAPPQNVSLEVVNSRSIKVSWLPPPSGT 650
Query: 657 NNSPITKFIIEYE--------DAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAV 708
N IT + I + + + LW+ T G + +Q YSF+V A+
Sbjct: 651 QNGFITGYKIRHRKTTRRGEMETLEPNNLWYLFT---GLEKGSQ--------YSFQVSAM 699
Query: 709 NSIGKSLPS-----EASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKP-------LNG 756
G PS E E L ++ PD+ P+++ + + + ++++W P + G
Sbjct: 700 TVNGTGPPSNWYTAETPENDLDESQVPDQ-PSSLH-VRPQTNCIIMSWTPPLNPNIVVRG 757
Query: 757 F-ESNGPGLQYKVSWRQKDGDDEWTSVVVANVSKYIVS---------GTPTFVPYLIK-- 804
+ G G Y + R ++ + + S Y++S G P + +
Sbjct: 758 YIIGYGVGSPYAETVRVDSKQRYYSIERLESSSHYVISLKAFNNAGEGVPLYESATTRSI 817
Query: 805 VQALNDMGFAP----EPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHW--DPVPLKSI 858
+ + + P P V S PM+ P V+ + V W + VP
Sbjct: 818 TDPTDPVDYYPLLDDFPTSVPDLS---TPMLPPVGVQAVALTHDAVRVSWADNSVPKNQK 874
Query: 859 RGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGK 918
++ Y + W+T S+ + + L++ + GL+P + Y +V V +
Sbjct: 875 TSEVRLYTV-RWRTSFSASAKYKSEDTTSLSYTAT-------GLKPNTMYEFSVMVTKNR 926
Query: 919 GEGPASPDRVFNTPEGVP-SAPSSLKIV--NPTLDSLTLEWDPPSHPNGILTEYTLKYQP 975
S T E P SAP L ++ ++ + W PP NG +T Y L Y
Sbjct: 927 RSSTWSMTAHATTYEAAPTSAPKDLTVITREGKPRAVIVSWQPPLEANGKITAYILFY-T 985
Query: 976 INSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSG 1021
++ + + I ++ + +LN T Y F A+ S G G
Sbjct: 986 LDKNIPIDDWIMETISGDRLTHQIMDLNLDTMYYFRIQARNSKGVG 1031
Score = 43.1 bits (100), Expect = 0.002
Identities = 34/141 (24%), Positives = 57/141 (40%), Gaps = 13/141 (9%)
Query: 45 QSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMS 104
Q P + + ++ V++C G PPPSF+W R + + ++ G+ LI N+
Sbjct: 244 QRPSNVVAIEGKDAVLECCVSGYPPPSFTWLRGEEVIQL-RSKKYSLLGGSNLLISNVTD 302
Query: 105 EGKAETYEGVYQC--TARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCR 162
+ G+Y C T +NE +A + V+ P W + + C
Sbjct: 303 DD-----SGMYTCVVTYKNENISASAELTVLVPP----WFLNHPSNLYAYESMDIEFECT 353
Query: 163 PPIGLPPPIIFWMDNSFQRLP 183
G P P + WM N +P
Sbjct: 354 VS-GKPVPTVNWMKNGDVVIP 373
Score = 35.4 bits (80), Expect = 0.32
Identities = 71/332 (21%), Positives = 124/332 (37%), Gaps = 45/332 (13%)
Query: 630 VPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQT 689
VP+ P L + Q + + +SWTP + N + +II Y + P + V Q
Sbjct: 725 VPDQPSSLHVRPQTN-CIIMSWTPPLNPNIVVRGYIIGY--GVGSP--YAETVRVDSKQR 779
Query: 690 TAQL-KLSPYVNYSFRVMAVNSIGKSLP--SEASEQYLTKASEP-------DKNPTAVEG 739
+ +L +Y + A N+ G+ +P A+ + +T ++P D PT+V
Sbjct: 780 YYSIERLESSSHYVISLKAFNNAGEGVPLYESATTRSITDPTDPVDYYPLLDDFPTSVPD 839
Query: 740 LGSEP-------------DNLVITWKPLNGFESNGPGLQ---YKVSWRQK-DGDDEWTSV 782
L + D + ++W N N + Y V WR ++ S
Sbjct: 840 LSTPMLPPVGVQAVALTHDAVRVSWAD-NSVPKNQKTSEVRLYTVRWRTSFSASAKYKSE 898
Query: 783 VVANVSKYIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVN 842
++S Y +G Y V + + + E P AP ++ V
Sbjct: 899 DTTSLS-YTATGLKPNTMYEFSVMVTKNRRSSTWSMTAHATTYEAAPTSAPKDLTVITRE 957
Query: 843 ST--LAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKIL-TFQGSKTHGML 899
V W P PL++ G + Y ++Y ++ I+ I+ T G + +
Sbjct: 958 GKPRAVIVSWQP-PLEA-NGKITAYILFYTLDKNIP------IDDWIMETISGDRLTHQI 1009
Query: 900 PGLEPFSHYTLNVRVVNGKGEGPASPDRVFNT 931
L + Y ++ N KG GP S +F T
Sbjct: 1010 MDLNLDTMYYFRIQARNSKGVGPLSDPILFRT 1041
Score = 33.9 bits (76), Expect = 0.94
Identities = 36/119 (30%), Positives = 54/119 (45%), Gaps = 5/119 (4%)
Query: 618 SVSASAVLSVVDVPNPPFDLELTDQLDK--SVQLSWTPGDDNNSPITKFIIEYEDAMHKP 675
S++A A + P DL + + K +V +SW P + N IT +I+ Y + P
Sbjct: 932 SMTAHATTYEAAPTSAPKDLTVITREGKPRAVIVSWQPPLEANGKITAYILFYTLDKNIP 991
Query: 676 -GLWHHQTEVSGTQTTAQLK-LSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDK 732
W +T +SG + T Q+ L+ Y FR+ A NS G S+ K PDK
Sbjct: 992 IDDWIMET-ISGDRLTHQIMDLNLDTMYYFRIQARNSKGVGPLSDPILFRTLKVEHPDK 1049
>gi|109633041 protein tyrosine phosphatase, receptor type, F isoform 1
precursor [Homo sapiens]
Length = 1907
Score = 201 bits (510), Expect = 4e-51
Identities = 192/719 (26%), Positives = 317/719 (44%), Gaps = 64/719 (8%)
Query: 355 PYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFS 414
P +I P++ G + +C+A G PKPRI+W+ G + + DG +
Sbjct: 33 PVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVL- 91
Query: 415 NVQ----ERSSAVYQCNASNEYGYLLANAFVNVLAE---PPRI--LTPANTLYQVIANRP 465
+Q +R A+Y+C A+N G + +A ++VL E PP + L V R
Sbjct: 92 RIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKART 151
Query: 466 ALLDCAFFGSPLPTIEWFKG--AKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARN 523
A + CA G+P P I WFK A +G L+I +++ G Y CVA N
Sbjct: 152 ATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSGALQIESSEESDQGKYECVATN 211
Query: 524 KLGM-----AKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKD 578
G A V + P + + P V G V+ C V W+
Sbjct: 212 SAGTRYSAPANLYVRVRRVAPRFSIP-PSSQEVMPGGSVNLTCVAVG--APMPYVKWMMG 268
Query: 579 NRELPSDERFTVDKDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVDVPNPPFDLE 638
EL ++ V ++ L +++V S YTCVA ++L + A+A ++V +P PP DL
Sbjct: 269 AEELTKEDEMPVGRNVLELSNVVR--SANYTCVAISSLGMIEATAQVTVKALPKPPIDLV 326
Query: 639 LTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQL--KLS 696
+T+ SV L+W G N+ P+T + I+Y A G EV G TT LS
Sbjct: 327 VTETTATSVTLTWDSG--NSEPVTYYGIQYRAA----GTEGPFQEVDGVATTRYSIGGLS 380
Query: 697 PYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNG 756
P+ Y+FRV+AVNSIG+ PSEA + T P P V+ +++ W+P
Sbjct: 381 PFSEYAFRVLAVNSIGRGPPSEA-VRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPE- 438
Query: 757 FESNGPGLQYKVSWR--QKDGDDEWTSVVVANVSKYIVSGTPTFVP---YLIKVQALNDM 811
E NG Y+V + + + W N +++ + +P Y ++V A +
Sbjct: 439 -EPNGLVRGYRVYYTPDSRRPPNAWHK---HNTDAGLLTTVGSLLPGITYSLRVLAFTAV 494
Query: 812 GFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWK 871
G P + + + +P P + + V + T ++ W P + I Y + YW
Sbjct: 495 GDGPPSPTIQVKTQQGVP-AQPADFQAEVESDTRIQLSWLLPPQERI----IMYELVYWA 549
Query: 872 TQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNT 931
+ ++++ +TF + ++ L L+P + Y + + G G +P T
Sbjct: 550 AEDEDQQHK-------VTFDPTSSY-TLEDLKPDTLYRFQLAARSDMGVGVFTPTIEART 601
Query: 932 PEGVPSAPSSLKIVNPTLDSLT--LEWDPP--SHPNGILTEYTLKYQPINSTHELGPLVD 987
+ PSAP K++ ++ S T + W PP NG++T+Y++ Y+ ++ +VD
Sbjct: 602 AQSTPSAPPQ-KVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVD 660
Query: 988 LKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEEAVTTVDEAMAS---RQVDI 1043
I + W L L T Y+ + A T G G + + V T DE + S R+V++
Sbjct: 661 -GISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRT-DEDVPSGPPRKVEV 717
Score = 173 bits (439), Expect = 8e-43
Identities = 181/795 (22%), Positives = 309/795 (38%), Gaps = 63/795 (7%)
Query: 277 LRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEK------TLQIIHVSEADSG 330
L G V S C A G P P I W K+ + R F+ +Q + V + D
Sbjct: 45 LSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRV-QRDEA 103
Query: 331 NYQCIAKNALGAIHHTISVRV-------KAAPYWITAPQNLVLSPGEDGTLICRANGNPK 383
Y+C A N+LG I+ + + V P PQ V+ T++C A GNP
Sbjct: 104 IYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGGNPD 163
Query: 384 PRISWLTNGVPIEIAPDDPS-RKIDGDTIIFSNVQERSSAVYQCNASNEYGYLL---ANA 439
P ISW + +P++ A + +++ + + +E Y+C A+N G AN
Sbjct: 164 PEISWFKDFLPVDPATSNGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPANL 223
Query: 440 FVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLH 499
+V V PR P ++ +V+ L C G+P+P ++W GA+ +++ V
Sbjct: 224 YVRVRRVAPRFSIPPSS-QEVMPGGSVNLTCVAVGAPMPYVKWMMGAEELTKEDEMPV-- 280
Query: 500 ENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSF 559
G + ++ + YTCVA + LGM + + +K + K P VV + S
Sbjct: 281 --GRNVLELSNVVRSANYTCVAISSLGMIEATAQVTVKA---LPKPPIDLVVTETTATSV 335
Query: 560 ECKVKHDHTLSLT---VLWLKDNRELPSDERFTVDKDHLVVADVSDDDSGTYTCVANTTL 616
++ +T + + E P E V + +S + +A ++
Sbjct: 336 TLTWDSGNSEPVTYYGIQYRAAGTEGPFQEVDGVATTRYSIGGLSPFSEYAFRVLAVNSI 395
Query: 617 ----DSVSASAVLSVVDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEY-EDA 671
S + A +PP ++ ++ + W P ++ N + + + Y D+
Sbjct: 396 GRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPEEPNGLVRGYRVYYTPDS 455
Query: 672 MHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPD 731
P WH +G TT L P + YS RV+A ++G PS + Q T+ P
Sbjct: 456 RRPPNAWHKHNTDAGLLTTVG-SLLPGITYSLRVLAFTAVGDGPPS-PTIQVKTQQGVP- 512
Query: 732 KNPTAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDEWTSVVVANVSKYI 791
P + + ++W + Y++ + + +D+ V S Y
Sbjct: 513 AQPADFQAEVESDTRIQLSWL----LPPQERIIMYELVYWAAEDEDQQHKVTFDPTSSYT 568
Query: 792 VSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWD 851
+ Y ++ A +DMG + + + P P V + ST V W
Sbjct: 569 LEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRVSWV 628
Query: 852 PVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGM--LPGLEPFSHYT 909
P P S G + Y + Y + RH+ I S+ H L GLE ++ Y
Sbjct: 629 PPPADSRNGVITQYSVAYEAVDGEDR--GRHVVDGI-----SREHSSWDLVGLEKWTEYR 681
Query: 910 LNVRVVNGKGEGPASPDRVFNTPEGVPSAPS---SLKIVNPTLDSLTLEWDPPSHPNGIL 966
+ VR G GP S + T E VPS P ++ +N T + + PS +G +
Sbjct: 682 VWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQI 741
Query: 967 TEYTLKYQPINSTHELGPLVDLKIPANKTRW----------TLKNLNFSTRYKFYFYAQT 1016
Y + Y + + G + + + +W T+ L T Y A T
Sbjct: 742 RGYQVTYVRLENGEPRGLPIIQDVMLAEAQWRPEESEDYETTISGLTPETTYSVTVAAYT 801
Query: 1017 SAGSGSQITEEAVTT 1031
+ G G++ + VTT
Sbjct: 802 TKGDGARSKPKIVTT 816
Score = 125 bits (313), Expect = 3e-28
Identities = 219/1030 (21%), Positives = 374/1030 (36%), Gaps = 156/1030 (15%)
Query: 62 CEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQCTARN 121
C+A G+P P +W + G + ++ G G+++ + + + E +Y+CTA N
Sbjct: 54 CQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLR--IQPLRVQRDEAIYECTATN 111
Query: 122 ERG---AAVSNNIVVRPSRSPLWTKEKLEPI--TLQSGQSLVLPCRPPIGLPPPIIFWMD 176
G + +++ P + + P ++ ++ + C G P P I W
Sbjct: 112 SLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAG-GNPDPEISWFK 170
Query: 177 NSFQRLPQSE--RVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVIS 234
+ P + R+ Q +G L + E + Y C A + + V+V
Sbjct: 171 DFLPVDPATSNGRIKQLRSGALQIESS-EESDQGKYECVATNSAGTRYSAPANLYVRV-- 227
Query: 235 VDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTP 294
R P F P S++E + G ++L C+A G P P
Sbjct: 228 -----------------------RRVAPRFSIPP---SSQEVMPGGSVNLTCVAVGAPMP 261
Query: 295 IIYW-------AKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTI 347
+ W KED M P R V L++ +V S NY C+A ++LG I T
Sbjct: 262 YVKWMMGAEELTKEDEM-PVGRNV-------LELSNVVR--SANYTCVAISSLGMIEATA 311
Query: 348 SVRVKAAPYWITAPQNLVLS-PGEDGTLICRANGNPKPRISWLTNGVPIEIA-PDDPSRK 405
V VKA P P +LV++ + +GN +P + G+ A + P ++
Sbjct: 312 QVTVKALP---KPPIDLVVTETTATSVTLTWDSGNSEPVTYY---GIQYRAAGTEGPFQE 365
Query: 406 IDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIANRP 465
+DG V ++ + +EY + + A ++ PP A T Q ++ P
Sbjct: 366 VDG-------VATTRYSIGGLSPFSEYAFRVL-AVNSIGRGPPSEAVRARTGEQAPSSPP 417
Query: 466 ALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVA---QKDSTGTYTCVAR 522
+ + ++W + + L V + + P A G T V
Sbjct: 418 RRVQARMLSASTMLVQWEPPEEPNGLVRGYRVYYTPDSRRPPNAWHKHNTDAGLLTTVGS 477
Query: 523 NKLG-------MAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLW 575
G +A V PT VK + Q F+ +V+ D + L+ L
Sbjct: 478 LLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQ---PADFQAEVESDTRIQLSWLL 534
Query: 576 LKDNRELPSDERFTVDKDHLVVADVSDDDSGTYTC----------------------VAN 613
R + + + +D V+ D + +YT V
Sbjct: 535 PPQERIIMYELVYWAAEDEDQQHKVTFDPTSSYTLEDLKPDTLYRFQLAARSDMGVGVFT 594
Query: 614 TTLDSVSASAVLSVVDVPNPPFDLELTDQLDKSVQLSWT--PGDDNNSPITKFIIEYEDA 671
T+++ +A + S PP + +V++SW P D N IT++ + YE
Sbjct: 595 PTIEARTAQSTPSA-----PPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAV 649
Query: 672 MHKPGLWHHQTEVSGTQTTAQL-KLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASE- 729
+ H +S ++ L L + Y V A +G P S L + E
Sbjct: 650 DGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVG---PGPESSPVLVRTDED 706
Query: 730 -PDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDEWTSVVVANVS 788
P P VE + + WK + +G Y+V++ + + + ++ +V
Sbjct: 707 VPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVM 766
Query: 789 --------------KYIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPG 834
+ +SG Y + V A G + + +P
Sbjct: 767 LAEAQWRPEESEDYETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPTM 826
Query: 835 NVRVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSK 894
+ +N+ L + H P K + G L GYR+ Y + + + F
Sbjct: 827 MISTTAMNTALLQWH----PPKELPGELLGYRLQYCRADEA--------RPNTIDFGKDD 874
Query: 895 THGMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPSA-PSSLKIVNPTLDSLT 953
H + GL + Y + N G G ++ TPE +PS P +L + T +
Sbjct: 875 QHFTVTGLHKGTTYIFRLAAKNRAGLGEEF-EKEIRTPEDLPSGFPQNLHVTGLTTSTTE 933
Query: 954 LEWDPP--SHPNGILTEYTLKYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFY 1011
L WDPP + NG + YT+ ++ INS EL + TR+TL L T Y
Sbjct: 934 LAWDPPVLAERNGRIISYTVVFRDINSQQELQNI------TTDTRFTLTGLKPDTTYDIK 987
Query: 1012 FYAQTSAGSG 1021
A TS GSG
Sbjct: 988 VRAWTSKGSG 997
Score = 122 bits (305), Expect = 3e-27
Identities = 107/417 (25%), Positives = 174/417 (41%), Gaps = 27/417 (6%)
Query: 630 VPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFII---EYEDAMHKPGLWHHQTEVSG 686
VP P D + + D +QLSW + + + E ED HK + +
Sbjct: 511 VPAQPADFQAEVESDTRIQLSWLLPPQERIIMYELVYWAAEDEDQQHKVTF-----DPTS 565
Query: 687 TQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDN 746
+ T LK P Y F++ A + +G + + E T S P P V +
Sbjct: 566 SYTLEDLK--PDTLYRFQLAARSDMGVGVFTPTIEAR-TAQSTPSAPPQKVMCVSMGSTT 622
Query: 747 LVITWKPLNGFESNGPGLQYKVSWRQKDGDDEWTSVVVA---NVSKYIVSGTPTFVPYLI 803
+ ++W P NG QY V++ DG+D VV S + + G + Y +
Sbjct: 623 VRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEYRV 682
Query: 804 KVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWD-PVPLKSIRGHL 862
V+A D+G PE + V+ + ED+P P V V +NST V+W PVP K G +
Sbjct: 683 WVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQ-HGQI 741
Query: 863 QGYRIYYWKTQSSSKRNRRHIEKKILT------FQGSKTHGMLPGLEPFSHYTLNVRVVN 916
+GY++ Y + ++ R I+ +L + + GL P + Y++ V
Sbjct: 742 RGYQVTYVRLENGEPRGLPIIQDVMLAEAQWRPEESEDYETTISGLTPETTYSVTVAAYT 801
Query: 917 GKGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDPPSHPNGILTEYTLKYQPI 976
KG+G S ++ T VP P ++ I +++ L+W PP G L Y L+Y
Sbjct: 802 TKGDGARSKPKIVTTTGAVPGRP-TMMISTTAMNTALLQWHPPKELPGELLGYRLQYCRA 860
Query: 977 NSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEEAVTTVD 1033
+ + + +T+ L+ T Y F A+ AG G + +E T D
Sbjct: 861 DEARP----NTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEIRTPED 913
Score = 63.9 bits (154), Expect = 9e-10
Identities = 78/371 (21%), Positives = 142/371 (38%), Gaps = 37/371 (9%)
Query: 654 GDDNNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGK 713
G+ PI + ++ E ++T +SG L+P YS V A + G
Sbjct: 754 GEPRGLPIIQDVMLAEAQWRPEESEDYETTISG--------LTPETTYSVTVAAYTTKGD 805
Query: 714 SLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVSWRQK 773
S+ + +T PT + + + ++ W P E G L Y++ + +
Sbjct: 806 GARSKP--KIVTTTGAVPGRPTMMIST-TAMNTALLQWHPPK--ELPGELLGYRLQYCRA 860
Query: 774 DGDDEWTSVVVANVSKYIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAP 833
D T + + V+G Y+ ++ A N G E + + EDLP P
Sbjct: 861 DEARPNTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEI-RTPEDLPSGFP 919
Query: 834 GNVRVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGS 893
N+ V + ++ E+ WDP L G + Y + + +S++ ++I +
Sbjct: 920 QNLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVF--RDINSQQELQNIT--------T 969
Query: 894 KTHGMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLT 953
T L GL+P + Y + VR KG GP SP T + ++ S+
Sbjct: 970 DTRFTLTGLKPDTTYDIKVRAWTSKGSGPLSPSIQSRTMPVEQVFAKNFRVAAAMKTSVL 1029
Query: 954 LEWD-PPSHPNGILTEYTLKYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYF 1012
L W+ P S+ + + + Q + ++ + R + +L +T Y F
Sbjct: 1030 LSWEVPDSYKSAVPFKILYNGQSV------------EVDGHSMRKLIADLQPNTEYSFVL 1077
Query: 1013 YAQTSAGSGSQ 1023
+ S+ G Q
Sbjct: 1078 MNRGSSAGGLQ 1088
Score = 43.9 bits (102), Expect = 0.001
Identities = 52/231 (22%), Positives = 89/231 (38%), Gaps = 13/231 (5%)
Query: 47 PKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEG 106
P+ +++ + C A G P P SW ++ D + +G L I E
Sbjct: 141 PQLKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSGALQI----ES 196
Query: 107 KAETYEGVYQCTARNERGAAVS--NNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPP 164
E+ +G Y+C A N G S N+ VR R + G S+ L C
Sbjct: 197 SEESDQGKYECVATNSAGTRYSAPANLYVRVRRVAPRFSIPPSSQEVMPGGSVNLTC-VA 255
Query: 165 IGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQ 224
+G P P + WM + + L + + + G N L SNV+ +Y C A + I+
Sbjct: 256 VGAPMPYVKWMMGA-EELTKEDEMPVGRN-VLELSNVV---RSANYTCVA-ISSLGMIEA 309
Query: 225 KQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKE 275
++VK + ++ + + + S P T+ + A+ E
Sbjct: 310 TAQVTVKALPKPPIDLVVTETTATSVTLTWDSGNSEPVTYYGIQYRAAGTE 360
>gi|109633039 protein tyrosine phosphatase, receptor type, F isoform 2
precursor [Homo sapiens]
Length = 1898
Score = 201 bits (510), Expect = 4e-51
Identities = 192/719 (26%), Positives = 317/719 (44%), Gaps = 64/719 (8%)
Query: 355 PYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFS 414
P +I P++ G + +C+A G PKPRI+W+ G + + DG +
Sbjct: 33 PVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVL- 91
Query: 415 NVQ----ERSSAVYQCNASNEYGYLLANAFVNVLAE---PPRI--LTPANTLYQVIANRP 465
+Q +R A+Y+C A+N G + +A ++VL E PP + L V R
Sbjct: 92 RIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKART 151
Query: 466 ALLDCAFFGSPLPTIEWFKG--AKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARN 523
A + CA G+P P I WFK A +G L+I +++ G Y CVA N
Sbjct: 152 ATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSGALQIESSEESDQGKYECVATN 211
Query: 524 KLGM-----AKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKD 578
G A V + P + + P V G V+ C V W+
Sbjct: 212 SAGTRYSAPANLYVRVRRVAPRFSIP-PSSQEVMPGGSVNLTCVAVG--APMPYVKWMMG 268
Query: 579 NRELPSDERFTVDKDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVDVPNPPFDLE 638
EL ++ V ++ L +++V S YTCVA ++L + A+A ++V +P PP DL
Sbjct: 269 AEELTKEDEMPVGRNVLELSNVVR--SANYTCVAISSLGMIEATAQVTVKALPKPPIDLV 326
Query: 639 LTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQL--KLS 696
+T+ SV L+W G N+ P+T + I+Y A G EV G TT LS
Sbjct: 327 VTETTATSVTLTWDSG--NSEPVTYYGIQYRAA----GTEGPFQEVDGVATTRYSIGGLS 380
Query: 697 PYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNG 756
P+ Y+FRV+AVNSIG+ PSEA + T P P V+ +++ W+P
Sbjct: 381 PFSEYAFRVLAVNSIGRGPPSEA-VRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPE- 438
Query: 757 FESNGPGLQYKVSWR--QKDGDDEWTSVVVANVSKYIVSGTPTFVP---YLIKVQALNDM 811
E NG Y+V + + + W N +++ + +P Y ++V A +
Sbjct: 439 -EPNGLVRGYRVYYTPDSRRPPNAWHK---HNTDAGLLTTVGSLLPGITYSLRVLAFTAV 494
Query: 812 GFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWK 871
G P + + + +P P + + V + T ++ W P + I Y + YW
Sbjct: 495 GDGPPSPTIQVKTQQGVP-AQPADFQAEVESDTRIQLSWLLPPQERI----IMYELVYWA 549
Query: 872 TQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNT 931
+ ++++ +TF + ++ L L+P + Y + + G G +P T
Sbjct: 550 AEDEDQQHK-------VTFDPTSSY-TLEDLKPDTLYRFQLAARSDMGVGVFTPTIEART 601
Query: 932 PEGVPSAPSSLKIVNPTLDSLT--LEWDPP--SHPNGILTEYTLKYQPINSTHELGPLVD 987
+ PSAP K++ ++ S T + W PP NG++T+Y++ Y+ ++ +VD
Sbjct: 602 AQSTPSAPPQ-KVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVD 660
Query: 988 LKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEEAVTTVDEAMAS---RQVDI 1043
I + W L L T Y+ + A T G G + + V T DE + S R+V++
Sbjct: 661 -GISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRT-DEDVPSGPPRKVEV 717
Score = 177 bits (450), Expect = 4e-44
Identities = 182/786 (23%), Positives = 309/786 (39%), Gaps = 54/786 (6%)
Query: 277 LRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEK------TLQIIHVSEADSG 330
L G V S C A G P P I W K+ + R F+ +Q + V + D
Sbjct: 45 LSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRV-QRDEA 103
Query: 331 NYQCIAKNALGAIHHTISVRV-------KAAPYWITAPQNLVLSPGEDGTLICRANGNPK 383
Y+C A N+LG I+ + + V P PQ V+ T++C A GNP
Sbjct: 104 IYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGGNPD 163
Query: 384 PRISWLTNGVPIEIAPDDPS-RKIDGDTIIFSNVQERSSAVYQCNASNEYGYLL---ANA 439
P ISW + +P++ A + +++ + + +E Y+C A+N G AN
Sbjct: 164 PEISWFKDFLPVDPATSNGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPANL 223
Query: 440 FVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLH 499
+V V PR P ++ +V+ L C G+P+P ++W GA+ +++ V
Sbjct: 224 YVRVRRVAPRFSIPPSS-QEVMPGGSVNLTCVAVGAPMPYVKWMMGAEELTKEDEMPV-- 280
Query: 500 ENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSF 559
G + ++ + YTCVA + LGM + + +K + K P VV + S
Sbjct: 281 --GRNVLELSNVVRSANYTCVAISSLGMIEATAQVTVKA---LPKPPIDLVVTETTATSV 335
Query: 560 ECKVKHDHTLSLT---VLWLKDNRELPSDERFTVDKDHLVVADVSDDDSGTYTCVANTTL 616
++ +T + + E P E V + +S + +A ++
Sbjct: 336 TLTWDSGNSEPVTYYGIQYRAAGTEGPFQEVDGVATTRYSIGGLSPFSEYAFRVLAVNSI 395
Query: 617 ----DSVSASAVLSVVDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEY-EDA 671
S + A +PP ++ ++ + W P ++ N + + + Y D+
Sbjct: 396 GRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPEEPNGLVRGYRVYYTPDS 455
Query: 672 MHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPD 731
P WH +G TT L P + YS RV+A ++G PS + Q T+ P
Sbjct: 456 RRPPNAWHKHNTDAGLLTTVG-SLLPGITYSLRVLAFTAVGDGPPS-PTIQVKTQQGVP- 512
Query: 732 KNPTAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDEWTSVVVANVSKYI 791
P + + ++W + Y++ + + +D+ V S Y
Sbjct: 513 AQPADFQAEVESDTRIQLSWL----LPPQERIIMYELVYWAAEDEDQQHKVTFDPTSSYT 568
Query: 792 VSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWD 851
+ Y ++ A +DMG + + + P P V + ST V W
Sbjct: 569 LEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRVSWV 628
Query: 852 PVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGM--LPGLEPFSHYT 909
P P S G + Y + Y + RH+ I S+ H L GLE ++ Y
Sbjct: 629 PPPADSRNGVITQYSVAYEAVDGEDR--GRHVVDGI-----SREHSSWDLVGLEKWTEYR 681
Query: 910 LNVRVVNGKGEGPASPDRVFNTPEGVPSAPS---SLKIVNPTLDSLTLEWDPPSHPNGIL 966
+ VR G GP S + T E VPS P ++ +N T + + PS +G +
Sbjct: 682 VWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQI 741
Query: 967 TEYTLKYQPINSTHELG-PLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQIT 1025
Y + Y + + G P++ + A T+ L T Y A T+ G G++
Sbjct: 742 RGYQVTYVRLENGEPRGLPIIQDVMLAEAQETTISGLTPETTYSVTVAAYTTKGDGARSK 801
Query: 1026 EEAVTT 1031
+ VTT
Sbjct: 802 PKIVTT 807
Score = 132 bits (332), Expect = 2e-30
Identities = 222/1021 (21%), Positives = 376/1021 (36%), Gaps = 147/1021 (14%)
Query: 62 CEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQCTARN 121
C+A G+P P +W + G + ++ G G+++ + + + E +Y+CTA N
Sbjct: 54 CQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLR--IQPLRVQRDEAIYECTATN 111
Query: 122 ERG---AAVSNNIVVRPSRSPLWTKEKLEPI--TLQSGQSLVLPCRPPIGLPPPIIFWMD 176
G + +++ P + + P ++ ++ + C G P P I W
Sbjct: 112 SLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAG-GNPDPEISWFK 170
Query: 177 NSFQRLPQSE--RVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVIS 234
+ P + R+ Q +G L + E + Y C A + + V+V
Sbjct: 171 DFLPVDPATSNGRIKQLRSGALQIESS-EESDQGKYECVATNSAGTRYSAPANLYVRV-- 227
Query: 235 VDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTP 294
R P F P S++E + G ++L C+A G P P
Sbjct: 228 -----------------------RRVAPRFSIPP---SSQEVMPGGSVNLTCVAVGAPMP 261
Query: 295 IIYW-------AKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTI 347
+ W KED M P R V L++ +V S NY C+A ++LG I T
Sbjct: 262 YVKWMMGAEELTKEDEM-PVGRNV-------LELSNVVR--SANYTCVAISSLGMIEATA 311
Query: 348 SVRVKAAPYWITAPQNLVLS-PGEDGTLICRANGNPKPRISWLTNGVPIEIA-PDDPSRK 405
V VKA P P +LV++ + +GN +P + G+ A + P ++
Sbjct: 312 QVTVKALP---KPPIDLVVTETTATSVTLTWDSGNSEPVTYY---GIQYRAAGTEGPFQE 365
Query: 406 IDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIANRP 465
+DG V ++ + +EY + + A ++ PP A T Q ++ P
Sbjct: 366 VDG-------VATTRYSIGGLSPFSEYAFRVL-AVNSIGRGPPSEAVRARTGEQAPSSPP 417
Query: 466 ALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVA---QKDSTGTYTCVAR 522
+ + ++W + + L V + + P A G T V
Sbjct: 418 RRVQARMLSASTMLVQWEPPEEPNGLVRGYRVYYTPDSRRPPNAWHKHNTDAGLLTTVGS 477
Query: 523 NKLG-------MAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLW 575
G +A V PT VK + Q F+ +V+ D + L+ L
Sbjct: 478 LLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQ---PADFQAEVESDTRIQLSWLL 534
Query: 576 LKDNRELPSDERFTVDKDHLVVADVSDDDSGTYTC----------------------VAN 613
R + + + +D V+ D + +YT V
Sbjct: 535 PPQERIIMYELVYWAAEDEDQQHKVTFDPTSSYTLEDLKPDTLYRFQLAARSDMGVGVFT 594
Query: 614 TTLDSVSASAVLSVVDVPNPPFDLELTDQLDKSVQLSWT--PGDDNNSPITKFIIEYEDA 671
T+++ +A + S PP + +V++SW P D N IT++ + YE
Sbjct: 595 PTIEARTAQSTPSA-----PPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAV 649
Query: 672 MHKPGLWHHQTEVSGTQTTAQL-KLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASE- 729
+ H +S ++ L L + Y V A +G P S L + E
Sbjct: 650 DGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVG---PGPESSPVLVRTDED 706
Query: 730 -PDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVSW-RQKDGDDEW----TSVV 783
P P VE + + WK + +G Y+V++ R ++G+ V+
Sbjct: 707 VPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVM 766
Query: 784 VANVSKYIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNS 843
+A + +SG Y + V A G + + +P + +N+
Sbjct: 767 LAEAQETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAMNT 826
Query: 844 TLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLE 903
L + H P K + G L GYR+ Y + + + F H + GL
Sbjct: 827 ALLQWH----PPKELPGELLGYRLQYCRADEA--------RPNTIDFGKDDQHFTVTGLH 874
Query: 904 PFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPSA-PSSLKIVNPTLDSLTLEWDPP--S 960
+ Y + N G G ++ TPE +PS P +L + T + L WDPP +
Sbjct: 875 KGTTYIFRLAAKNRAGLGEEF-EKEIRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLA 933
Query: 961 HPNGILTEYTLKYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGS 1020
NG + YT+ ++ INS EL + TR+TL L T Y A TS GS
Sbjct: 934 ERNGRIISYTVVFRDINSQQELQNI------TTDTRFTLTGLKPDTTYDIKVRAWTSKGS 987
Query: 1021 G 1021
G
Sbjct: 988 G 988
Score = 125 bits (313), Expect = 3e-28
Identities = 108/411 (26%), Positives = 174/411 (42%), Gaps = 24/411 (5%)
Query: 630 VPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFII---EYEDAMHKPGLWHHQTEVSG 686
VP P D + + D +QLSW + + + E ED HK + +
Sbjct: 511 VPAQPADFQAEVESDTRIQLSWLLPPQERIIMYELVYWAAEDEDQQHKVTF-----DPTS 565
Query: 687 TQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDN 746
+ T LK P Y F++ A + +G + + E T S P P V +
Sbjct: 566 SYTLEDLK--PDTLYRFQLAARSDMGVGVFTPTIEAR-TAQSTPSAPPQKVMCVSMGSTT 622
Query: 747 LVITWKPLNGFESNGPGLQYKVSWRQKDGDDEWTSVVVA---NVSKYIVSGTPTFVPYLI 803
+ ++W P NG QY V++ DG+D VV S + + G + Y +
Sbjct: 623 VRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEYRV 682
Query: 804 KVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWD-PVPLKSIRGHL 862
V+A D+G PE + V+ + ED+P P V V +NST V+W PVP K G +
Sbjct: 683 WVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQ-HGQI 741
Query: 863 QGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGP 922
+GY++ Y + ++ R I+ +L T + GL P + Y++ V KG+G
Sbjct: 742 RGYQVTYVRLENGEPRGLPIIQDVMLAEAQETT---ISGLTPETTYSVTVAAYTTKGDGA 798
Query: 923 ASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDPPSHPNGILTEYTLKYQPINSTHEL 982
S ++ T VP P ++ I +++ L+W PP G L Y L+Y +
Sbjct: 799 RSKPKIVTTTGAVPGRP-TMMISTTAMNTALLQWHPPKELPGELLGYRLQYCRADEARP- 856
Query: 983 GPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEEAVTTVD 1033
+ + +T+ L+ T Y F A+ AG G + +E T D
Sbjct: 857 ---NTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEIRTPED 904
Score = 62.8 bits (151), Expect = 2e-09
Identities = 73/337 (21%), Positives = 130/337 (38%), Gaps = 29/337 (8%)
Query: 688 QTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNL 747
Q T L+P YS V A + G S+ + +T PT + + +
Sbjct: 771 QETTISGLTPETTYSVTVAAYTTKGDGARSKP--KIVTTTGAVPGRPTMMIST-TAMNTA 827
Query: 748 VITWKPLNGFESNGPGLQYKVSWRQKDGDDEWTSVVVANVSKYIVSGTPTFVPYLIKVQA 807
++ W P E G L Y++ + + D T + + V+G Y+ ++ A
Sbjct: 828 LLQWHPPK--ELPGELLGYRLQYCRADEARPNTIDFGKDDQHFTVTGLHKGTTYIFRLAA 885
Query: 808 LNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIRGHLQGYRI 867
N G E + + EDLP P N+ V + ++ E+ WDP L G + Y +
Sbjct: 886 KNRAGLGEEFEKEI-RTPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAERNGRIISYTV 944
Query: 868 YYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASPDR 927
+ +S++ ++I + T L GL+P + Y + VR KG GP SP
Sbjct: 945 VF--RDINSQQELQNIT--------TDTRFTLTGLKPDTTYDIKVRAWTSKGSGPLSPSI 994
Query: 928 VFNTPEGVPSAPSSLKIVNPTLDSLTLEWD-PPSHPNGILTEYTLKYQPINSTHELGPLV 986
T + ++ S+ L W+ P S+ + + + Q +
Sbjct: 995 QSRTMPVEQVFAKNFRVAAAMKTSVLLSWEVPDSYKSAVPFKILYNGQSV---------- 1044
Query: 987 DLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQ 1023
++ + R + +L +T Y F + S+ G Q
Sbjct: 1045 --EVDGHSMRKLIADLQPNTEYSFVLMNRGSSAGGLQ 1079
Score = 43.9 bits (102), Expect = 0.001
Identities = 52/231 (22%), Positives = 89/231 (38%), Gaps = 13/231 (5%)
Query: 47 PKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEG 106
P+ +++ + C A G P P SW ++ D + +G L I E
Sbjct: 141 PQLKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSGALQI----ES 196
Query: 107 KAETYEGVYQCTARNERGAAVS--NNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPP 164
E+ +G Y+C A N G S N+ VR R + G S+ L C
Sbjct: 197 SEESDQGKYECVATNSAGTRYSAPANLYVRVRRVAPRFSIPPSSQEVMPGGSVNLTC-VA 255
Query: 165 IGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQ 224
+G P P + WM + + L + + + G N L SNV+ +Y C A + I+
Sbjct: 256 VGAPMPYVKWMMGA-EELTKEDEMPVGRN-VLELSNVV---RSANYTCVA-ISSLGMIEA 309
Query: 225 KQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKE 275
++VK + ++ + + + S P T+ + A+ E
Sbjct: 310 TAQVTVKALPKPPIDLVVTETTATSVTLTWDSGNSEPVTYYGIQYRAAGTE 360
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 197 bits (501), Expect = 5e-50
Identities = 168/601 (27%), Positives = 256/601 (42%), Gaps = 75/601 (12%)
Query: 32 VPLDLVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTM 91
V L + +PP I Q P + + I++ CEA G P P +W + G + + +
Sbjct: 3980 VTLHVHEPPVI-QPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVL 4038
Query: 92 KPGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSN---NIVVRPSRSPLWTKEKLEP 148
P G I + E G Y C A+N G A+ N+ V P SP L+
Sbjct: 4039 -PSGGLQISRAVREDA-----GTYMCVAQNPAGTALGKIKLNVQVPPVISP-----HLKE 4087
Query: 149 ITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTRE 208
+ + + L C GLPPP I W + + + +S R +G L + V P D
Sbjct: 4088 YVIAVDKPITLSCEAD-GLPPPDITWHKDG-RAIVESIRQRVLSSGSLQIAFVQPGDAGH 4145
Query: 209 DYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPE 268
Y C +AAN++ + K + PP + E
Sbjct: 4146 -YTC-----------------------------MAANVAGSSSTSTKLTVHVPPRIRSTE 4175
Query: 269 GNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQII--HVSE 326
G+ + E + L C+A+G+PTP I W K+D +L N E ++I +V
Sbjct: 4176 GHYTVNENSQA---ILPCVADGIPTPAINW-KKDNVLLANLLGKYTAEPYGELILENVVL 4231
Query: 327 ADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRI 386
DSG Y C+A NA G HT+S+ V P + P ++ L+ GE L C+A G P P++
Sbjct: 4232 EDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKL 4291
Query: 387 SWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAE 446
+W N I P ++ V + S Y C A N G++ A FV V E
Sbjct: 4292 TWTFNN---NIIPAHFDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYV-KE 4347
Query: 447 PPRIL--TPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHE---- 500
PP P+N + + N A+L+C G P PTI+W KG DI + H
Sbjct: 4348 PPVFKGDYPSNWIEPLGGN--AILNCEVKGDPTPTIQW--NRKG----VDIEISHRIRQL 4399
Query: 501 -NGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSF 559
NG+L I + G YTCVA N+ G+ + + L ++ P I +P V+ G +
Sbjct: 4400 GNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITLEPVETVINAGGKIIL 4459
Query: 560 ECKVKHDHTLSLTVLWLKDNRELPSDERFTV-DKDHLVVADVSDDDSGTYTCVANTTLDS 618
C+ + T+ W + + D+R V + L +AD +D+ + CVA + S
Sbjct: 4460 NCQATGEP--QPTITWSRQGHSISWDDRVNVLSNNSLYIADAQKEDTSEFECVARNLMGS 4517
Query: 619 V 619
V
Sbjct: 4518 V 4518
Score = 179 bits (454), Expect = 1e-44
Identities = 177/660 (26%), Positives = 268/660 (40%), Gaps = 88/660 (13%)
Query: 62 CEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYE-GVYQCTAR 120
C G P PS +W R+G +D V+ T +++ ++ KAET + G Y C A
Sbjct: 3457 CITDGTPAPSMAWLRDGQPLGLDAHLTVS----THGMVLQLL---KAETEDSGKYTCIAS 3509
Query: 121 NERGAAVSNNIVVRPSRSP-LWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSF 179
NE G VS + +++ P + E+ E I++ L L C G+P P + WM +
Sbjct: 3510 NEAGE-VSKHFILKVLEPPHINGSEEHEEISVIVNNPLELTCIAS-GIPAPKMTWMKDG- 3566
Query: 180 QRLPQSERVSQGLNGD-LYFSNVLPEDTREDYICYARF---------------------- 216
+ LPQ+++V G+ L S EDT Y C A
Sbjct: 3567 RPLPQTDQVQTLGGGEVLRISTAQVEDTGR-YTCLASSPAGDDDKEYLVRVHVPPNIAGT 3625
Query: 217 ----------NHTQTIQQKQ-----PI--------------SVKVISVDELNDTIAANLS 247
N T++ K P+ V+++S A+L
Sbjct: 3626 DEPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILSGGRYLQINNADLG 3685
Query: 248 DTEFY-------GAKSSRERPPTFLTP---EGNASNKEELRGNVLSLECIAEGLPTPIIY 297
DT Y K++RE T P +G + L LECIAEG+PTP I
Sbjct: 3686 DTANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRIT 3745
Query: 298 WAKEDGMLPKNRTVYKNFEKTLQIIHVSEA---DSGNYQCIAKNALGAIHHTISVRVKAA 354
W K+ +L N Y E +H+ A D+G Y C+A NA G I ++V
Sbjct: 3746 WRKDGAVLAGNHARYSILENGF--LHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVP 3803
Query: 355 PYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPS-RKIDGDTIIF 413
P P N+ + TL C A G PKP I+W NG + + + S R + +++
Sbjct: 3804 PSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVI 3863
Query: 414 SNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFF 473
+ +A Y+C +N G V++ + P + T + V + PA++ C
Sbjct: 3864 ISPSVDDTATYECTVTNGAGD--DKRTVDLTVQVPPSIADEPTDFLVTKHAPAVITCTAS 3921
Query: 474 GSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVH 533
G P P+I W K D Y + +G +EI Q + G YTCVARN G A V
Sbjct: 3922 GVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVT 3981
Query: 534 LEIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDER--FTVD 591
L + +P I QP V + + C+ T S + W K+ + + R +
Sbjct: 3982 LHVHEPPVIQPQPSELHVILNNPILLPCEA--TGTPSPFITWQKEGINVNTSGRNHAVLP 4039
Query: 592 KDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVDVP-NPPFDLELTDQLDKSVQLS 650
L ++ +D+GTY CVA + L+V P P E +DK + LS
Sbjct: 4040 SGGLQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQVPPVISPHLKEYVIAVDKPITLS 4099
Score = 176 bits (447), Expect = 9e-44
Identities = 157/613 (25%), Positives = 247/613 (40%), Gaps = 56/613 (9%)
Query: 34 LDLVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKP 93
L++ PP++ ++ + I + CE G PPP SW +N ++ + L+
Sbjct: 2958 LNVHVPPSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGG 3017
Query: 94 GTGTLIINIMSEGKAETYEGVYQCTARNERGAA---VSNNIVVRPSRSPLWTKEKLEPIT 150
T +I +S+G G Y C A N+ G + S + V PS E L +
Sbjct: 3018 RTLQIIRAKVSDG------GEYTCIAINQAGESKKKFSLTVYVPPSIKD-HDSESLSVVN 3070
Query: 151 LQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDY 210
++ G S+ L C +PPP+I W N + + +S V +G + Y
Sbjct: 3071 VREGTSVSLECESN-AVPPPVITWYKNG-RMITESTHVEILADGQMLHIKKAEVSDTGQY 3128
Query: 211 ICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGN 270
+C A + V D+ N + + PP+ PE
Sbjct: 3129 VCRA---------------INVAGRDDKNFHLNVYV--------------PPSIEGPERE 3159
Query: 271 ASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNF---EKTLQIIHVSEA 327
E N ++L C A G+P P I W K + + ++ LQI +
Sbjct: 3160 VI--VETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHS 3217
Query: 328 DSGNYQCIAKNALGAI--HHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPR 385
DSGNY CIA N G ++ +S++V + P ++ + GE+ L+C ANG P P
Sbjct: 3218 DSGNYTCIASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPL 3277
Query: 386 ISWLTNGVPIEIAPDDPSR-KIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVL 444
I WL +G PI + R +G T+ + Y C A+N G +NV
Sbjct: 3278 IQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVY 3337
Query: 445 AEPP-RILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGT 503
P R + + ++C G+P P I W K L I +L
Sbjct: 3338 VTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQV 3397
Query: 504 LEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQ--PEYAVVQRGSMVSFEC 561
+ I AQ YTCVA N+ G+ +L++ P + E V +GS S C
Sbjct: 3398 IRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMAC 3457
Query: 562 KVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLV--VADVSDDDSGTYTCVANTTLDSV 619
D T + ++ WL+D + L D TV +V + +DSG YTC+A+ V
Sbjct: 3458 IT--DGTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEV 3515
Query: 620 SASAVLSVVDVPN 632
S +L V++ P+
Sbjct: 3516 SKHFILKVLEPPH 3528
Score = 175 bits (443), Expect = 3e-43
Identities = 160/618 (25%), Positives = 247/618 (39%), Gaps = 62/618 (10%)
Query: 32 VPLDLVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTM 91
V L++ PP I Q+ PK + + + I C A+G P P +W++ G+ +D + V+
Sbjct: 1163 VKLNVHVPPKI-QRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSN 1221
Query: 92 KPGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEP--- 148
GT L I+ + A G+Y C A N G I + P T E LEP
Sbjct: 1222 PDGT--LSIDQATPSDA----GIYTCVATNIAGTD-ETEITLHVQEPP--TVEDLEPPYN 1272
Query: 149 ITLQ---SGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLY-FSNVLPE 204
T Q + Q + PC P G P P I W+ N + + +S +G L ++V P
Sbjct: 1273 TTFQERVANQRIEFPC-PAKGTPKPTIKWLHNGRELTGREPGISILEDGTLLVIASVTPY 1331
Query: 205 DTREDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTF 264
D E YIC A N T ++K + V V P
Sbjct: 1332 DNGE-YICVA-VNEAGTTERKYNLKVHV-----------------------------PPV 1360
Query: 265 LTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYK-NFEKTLQIIH 323
+ + +N L + +L C EG P+PII W K++ + ++ T+ N K L++
Sbjct: 1361 IKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFR 1420
Query: 324 VSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITA--PQNLVLSPGEDGTLICRANGN 381
+ D+G Y C A N G ++ V P I P + + D L C+ G
Sbjct: 1421 ATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALECQVKGT 1480
Query: 382 PKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFV 441
P P I W +G P+ + + G + N + YQC SN G + +
Sbjct: 1481 PFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKL 1540
Query: 442 NVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHEN 501
+ P T V+ N L+C G P+P I W+K + + +
Sbjct: 1541 TIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKG 1600
Query: 502 GTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWI---VKQPEYAVVQRGSMVS 558
L IP AQ + TYTC N G A+ H+++ P I + P V ++
Sbjct: 1601 QYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIAHSLT 1660
Query: 559 FECKVKHDHTLSLTVLWLKDNRELPSDERFTVDK--DHLVVADVSDDDSGTYTCVANTTL 616
ECK + + LT WLKD + +++ ++ L + + D G Y CVA +
Sbjct: 1661 LECKAAGNPSPILT--WLKDGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVATSV- 1717
Query: 617 DSVSASAVLSVVDVPNPP 634
+ VDV PP
Sbjct: 1718 --AGEKEIKYEVDVLVPP 1733
Score = 167 bits (422), Expect = 7e-41
Identities = 147/578 (25%), Positives = 241/578 (41%), Gaps = 65/578 (11%)
Query: 58 IVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQC 117
I + CE+ G PPP+ W + G+ D V + G L I+I + A +Y C
Sbjct: 2214 ISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDA----ALYSC 2269
Query: 118 TARNERGAAVSN---NIVVRPSRSPLWTKEKLEP--ITLQSGQSLVLPCRPPIGLPPPII 172
A N G A + +RP+ T P I + G+S+ L C G+PPP +
Sbjct: 2270 VASNVAGTAKKEYNLQVYIRPTI----TNSGSHPTEIIVTRGKSISLECEVQ-GIPPPTV 2324
Query: 173 FWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKV 232
WM + + L N+ DT Y+C A N +K +SV
Sbjct: 2325 TWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGR-YVCVA-VNVAGMTDKKYDLSVHA 2382
Query: 233 ISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLP 292
PP+ + + N + N +SL C A G+P
Sbjct: 2383 ----------------------------PPSIIGNHRSPENISVVEKNSVSLTCEASGIP 2414
Query: 293 TPIIYWAKEDGMLPKNRTV-YKNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRV 351
P I W K+ + + +V + + L+++ + D+G Y C+ +NA G + V
Sbjct: 2415 LPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSV 2474
Query: 352 KAAPYWI--TAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGD 409
P+ + +++ + + TL C GNP P I+W +G P++ D+ I G
Sbjct: 2475 LVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQ--EDEAHHIISGG 2532
Query: 410 TII-FSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQ---VIANRP 465
+ +NVQ + Y C AS+ G+ + +NV P ++ + VI N P
Sbjct: 2533 RFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSP 2592
Query: 466 ALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKL 525
L C + P TI WFK + +I +L TL+I AQ+D+ G Y+CVA N+
Sbjct: 2593 TSLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEA 2652
Query: 526 GMAKNEVHLEIKDPTWIVK--------QPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLK 577
G +++ P I K P+ ++ + ++ EC+ + SL+ W K
Sbjct: 2653 GEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLS--WYK 2710
Query: 578 DNRELPSDERFTV--DKDHLVVADVSDDDSGTYTCVAN 613
D + L SD+ + + L + + D+G YTCVA+
Sbjct: 2711 DGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVAS 2748
Score = 162 bits (411), Expect = 1e-39
Identities = 171/683 (25%), Positives = 258/683 (37%), Gaps = 86/683 (12%)
Query: 59 VIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQCT 118
V++C+ G PPP W + ++ + + P G L I + A G Y C
Sbjct: 720 VMECKTSGIPPPQVKWFKGD--LELRPSTFLIIDPLLGLLKIQETQDLDA----GDYTCV 773
Query: 119 ARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFW--MD 176
A NE G A + I + P++ +E + ++++ G ++ LPC G P P I W +D
Sbjct: 774 AINEAGRA-TGKITLDVGSPPVFIQEPAD-VSMEIGSNVTLPCYVQ-GYPEPTIKWRRLD 830
Query: 177 NS--FQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVIS 234
N F R +SQ G L+ N+ D + YIC A N IQ + ++V +
Sbjct: 831 NMPIFSRPFSVSSISQLRTGALFILNLWASD-KGTYICEAE-NQFGKIQSETTVTVTGLV 888
Query: 235 VDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEELRGNVLSLEC-IAEGLPT 293
P ++P S + G L+L C + G P
Sbjct: 889 A-------------------------PLIGISP----SVANVIEGQQLTLPCTLLAGNPI 919
Query: 294 PIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKA 353
P W K ML +N + + +L I V D G Y C+A N G + T SV V
Sbjct: 920 PERRWIKNSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHV 979
Query: 354 APYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIF 413
P Q L G TL C+A+GNPKP + W G I + S DG +
Sbjct: 980 LPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVV 1039
Query: 414 SNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQ-------VIANRPA 466
S E S Y C A+N GY + V PR+ L Q V+A
Sbjct: 1040 SPGGEESGE-YVCTATNTAGYAKRKVQLTVYVR-PRVFGDQRGLSQDKPVEISVLAGEEV 1097
Query: 467 LLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLG 526
L C P P I W K + + + +G+++I + +G Y CVA N G
Sbjct: 1098 TLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAG 1157
Query: 527 MAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDE 586
V L + P I + P++ VQ G V C + T + W K + D
Sbjct: 1158 NVTQAVKLNVHVPPKIQRGPKHLKVQVGQRVDIPCNAQ--GTPLPVITWSKGGSTMLVDG 1215
Query: 587 RFTVDKDH--LVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVDVP-----NPPFDLEL 639
V L + + D+G YTCVA + L V + P PP++
Sbjct: 1216 EHHVSNPDGTLSIDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTF 1275
Query: 640 TDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQL------ 693
+++ P P K++ H+ E++G + +
Sbjct: 1276 QERVANQRIEFPCPAKGTPKPTIKWL-------------HNGRELTGREPGISILEDGTL 1322
Query: 694 ----KLSPYVNYSFRVMAVNSIG 712
++PY N + +AVN G
Sbjct: 1323 LVIASVTPYDNGEYICVAVNEAG 1345
Score = 162 bits (411), Expect = 1e-39
Identities = 155/597 (25%), Positives = 232/597 (38%), Gaps = 58/597 (9%)
Query: 39 PPTIT-QQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGT 97
PP I P+D + + ++C++ PPP +W RNG + P V + G
Sbjct: 3619 PPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPVITWLRNGER--LQATPRVRILSGGRY 3676
Query: 98 LIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSL 157
L IN G Y C A N G I+ P K + + + +S
Sbjct: 3677 LQINNADLGDTAN----YTCVASNIAGKTTREFILT--VNVPPNIKGGPQSLVILLNKST 3730
Query: 158 VLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFN 217
VL C G+P P I W + R S NG L+ + DT Y+C A N
Sbjct: 3731 VLECIAE-GVPTPRITWRKDGAVLAGNHARYSILENGFLHIQSAHVTDTGR-YLCMAT-N 3787
Query: 218 HTQTIQQKQPISVKV---ISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNK 274
T +++ + V V I+ N T+ N+ T
Sbjct: 3788 AAGTDRRRIDLQVHVPPSIAPGPTNMTVIVNVQTT------------------------- 3822
Query: 275 EELRGNVLSLECIAEGLPTPIIYWAKEDGML--PKNRTVYKNFEK-TLQIIHVSEADSGN 331
L C A G+P P I W K +L +N+ Y+ +L II S D+
Sbjct: 3823 ---------LACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTAT 3873
Query: 332 YQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTN 391
Y+C N G T+ + V+ P P + +++ + C A+G P P I W N
Sbjct: 3874 YECTVTNGAGDDKRTVDLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKN 3933
Query: 392 GVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRIL 451
G+ + + D R + I Q + Y C A N G A+ V + P ++
Sbjct: 3934 GIRL-LPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAG--SAHRHVTLHVHEPPVI 3990
Query: 452 TPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQK 511
P + VI N P LL C G+P P I W K + + +G L+I A +
Sbjct: 3991 QPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVR 4050
Query: 512 DSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSL 571
+ GTY CVA+N G A ++ L ++ P I + V+ ++ C+ D
Sbjct: 4051 EDAGTYMCVAQNPAGTALGKIKLNVQVPPVISPHLKEYVIAVDKPITLSCEA--DGLPPP 4108
Query: 572 TVLWLKDNRELPSDERFTV-DKDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSV 627
+ W KD R + R V L +A V D+G YTC+A S S S L+V
Sbjct: 4109 DITWHKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTV 4165
Score = 152 bits (383), Expect = 2e-36
Identities = 155/618 (25%), Positives = 255/618 (41%), Gaps = 67/618 (10%)
Query: 34 LDLVQPPTITQQSPKDYIIDPREN-IVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMK 92
L++ PP+I + ++ I++ N + + C+A G PPP+ +W +N H I+ + ++
Sbjct: 3145 LNVYVPPSI-EGPEREVIVETISNPVTLTCDATGIPPPTIAWLKN--HKRIENSDSLEVR 3201
Query: 93 PGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSN---NIVVRPSRSPLWTKEKLEPI 149
+G + I +++ G Y C A N G A +I V PS + E +
Sbjct: 3202 ILSGGSKLQIARSQHSDS--GNYTCIASNMEGKAQKYYFLSIQVPPSVAGA---EIPSDV 3256
Query: 150 TLQSGQSLVLPCRPPIGLPPPIIFWM-DNSFQRLPQSERVSQGLNGD-LYFSNVLPEDTR 207
++ G+++ L C G+P P+I W+ D ++ER+ NG L L DT
Sbjct: 3257 SVLLGENVELVCNAN-GIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTG 3315
Query: 208 EDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTP 267
+ Y C A T A D F ++TP
Sbjct: 3316 K-YTCVA--------------------------TNPAGEEDRIF--------NLNVYVTP 3340
Query: 268 --EGNASNKEELRGNV---LSLECIAEGLPTPIIYWAKEDGMLPKNRTV-YKNFEKTLQI 321
GN E+L V +++EC A G P P I W K LP + + + ++I
Sbjct: 3341 TIRGNKDEAEKLMTLVDTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRI 3400
Query: 322 IHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITA--PQNLVLSPGEDGTLICRAN 379
+ +D Y C+A N G + +++V A P + + + + G ++ C +
Sbjct: 3401 VRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITD 3460
Query: 380 GNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANA 439
G P P ++WL +G P+ + + G + + S Y C ASNE G + +
Sbjct: 3461 GTPAPSMAWLRDGQPLGLDAH-LTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHF 3519
Query: 440 FVNVLAEPPRIL-TPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVL 498
+ VL EPP I + + VI N P L C G P P + W K + + + L
Sbjct: 3520 ILKVL-EPPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTL 3578
Query: 499 HENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWI--VKQPEYAVVQRGSM 556
L I AQ + TG YTC+A + G E + + P I +P V R
Sbjct: 3579 GGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQ 3638
Query: 557 VSFECKVKHDHTLSLTVLWLKDNRELPSDERFTV--DKDHLVVADVSDDDSGTYTCVANT 614
V+ EC K D + WL++ L + R + +L + + D+ YTCVA+
Sbjct: 3639 VTLEC--KSDAVPPPVITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASN 3696
Query: 615 TLDSVSASAVLSVVDVPN 632
+ +L+V PN
Sbjct: 3697 IAGKTTREFILTVNVPPN 3714
Score = 150 bits (379), Expect = 7e-36
Identities = 157/618 (25%), Positives = 233/618 (37%), Gaps = 57/618 (9%)
Query: 22 FLCQMISAL-----EVPLDLVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTR 76
+LC +A + L + PP+I P + + + CEA G P PS +W +
Sbjct: 3781 YLCMATNAAGTDRRRIDLQVHVPPSIAP-GPTNMTVIVNVQTTLACEATGIPKPSINWRK 3839
Query: 77 NGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPS 136
NG ++D++ +G+L+I S TYE CT N GA V
Sbjct: 3840 NGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYE----CTVTN--GAGDDKRTVDLTV 3893
Query: 137 RSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDL 196
+ P ++ + V+ C G+P P I W N + LP+ GD
Sbjct: 3894 QVPPSIADEPTDFLVTKHAPAVITCTAS-GVPFPSIHWTKNGIRLLPR---------GDG 3943
Query: 197 YFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKS 256
Y +L E I + NH +A N + +
Sbjct: 3944 Y--RILSSGAIE--ILATQLNHAGRYT-----------------CVARNAAGSAHRHVTL 3982
Query: 257 SRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKED---GMLPKNRTVYK 313
PP + S + N + L C A G P+P I W KE +N V
Sbjct: 3983 HVHEPPVI---QPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLP 4039
Query: 314 NFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGT 373
+ LQI D+G Y C+A+N G I + V+ P + V++ + T
Sbjct: 4040 S--GGLQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQVPPVISPHLKEYVIAVDKPIT 4097
Query: 374 LICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYG 433
L C A+G P P I+W +G I R + ++ + VQ + Y C A+N G
Sbjct: 4098 LSCEADGLPPPDITWHKDG--RAIVESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAG 4155
Query: 434 YLLANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHE 493
+ + V PPRI + Y V N A+L C G P P I W K A
Sbjct: 4156 SSSTSTKLTVHV-PPRIRSTEGH-YTVNENSQAILPCVADGIPTPAINWKKDNVLLANLL 4213
Query: 494 DIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQR 553
Y G L + + +G YTCVA N G + V L + + P + +
Sbjct: 4214 GKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNK 4273
Query: 554 GSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVADVSDDDSGTYTCVAN 613
G + CK LT W +N +P+ LV+ VS +DSGTY C A
Sbjct: 4274 GEQLRLSCKATGIPLPKLT--WTFNNNIIPAHFDSVNGHSELVIERVSKEDSGTYVCTAE 4331
Query: 614 TTLDSVSASAVLSVVDVP 631
++ V A + V + P
Sbjct: 4332 NSVGFVKAIGFVYVKEPP 4349
Score = 145 bits (366), Expect = 2e-34
Identities = 190/862 (22%), Positives = 328/862 (38%), Gaps = 95/862 (11%)
Query: 34 LDLVQPPTITQQ--SPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTM 91
+D+ PP I +P + + ++ ++C+A G P P +W ++G + + +
Sbjct: 1633 VDVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVKANDN----I 1688
Query: 92 KPGTGTLIINIMSEGKAETYEGVYQCTARN---ERGAAVSNNIVVRPSRSPLWTKEKLEP 148
+ G + IMS + + G Y C A + E+ +++V P+ + ++
Sbjct: 1689 RIEAGGKKLEIMSAQEID--RGQYICVATSVAGEKEIKYEVDVLVPPA---IEGGDETSY 1743
Query: 149 ITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTRE 208
+ L L C G PPP I W+ + Q + + + LNG
Sbjct: 1744 FIVMVNNLLELDCHVT-GSPPPTIMWLKDG-QLIDERDGFKILLNG-------------- 1787
Query: 209 DYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPE 268
+K I+ +S L +AAN + + + PPT +
Sbjct: 1788 ---------------RKLVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTVHVPPTIKS-- 1830
Query: 269 GNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGML--PKNRTVYKNFEKTLQIIHVSE 326
S + ++ ++L+CIA G+P P I W K+D + + ++ + LQI
Sbjct: 1831 SGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGRVLQIAKTLL 1890
Query: 327 ADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQ--NLVLSPGEDGTLICRANGNPKP 384
D+G Y C+A NA G I + V P A + N + L C+A GNP P
Sbjct: 1891 EDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVP 1950
Query: 385 RISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVL 444
I+W + + + G I + Q + +Y+C A N G F ++
Sbjct: 1951 VITWYKDNRLLS-GSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAG--ATELFYSLQ 2007
Query: 445 AEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFK-GAKGSALHEDIYVLHENGT 503
++ +N + V+ N P L+C G P P++ W K G+ S+ + VL
Sbjct: 2008 VHVAPSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRI 2067
Query: 504 LEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFECKV 563
L + AQ TG YTCVA N G + ++ L + P I+ + + V V C+
Sbjct: 2068 LALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLCQ- 2126
Query: 564 KHDHTLSLTVLWLKDNRELPSDERFTVDKDHLV--VADVSDDDSGTYTCVANTTLDSVSA 621
D T+ WLKD L ++ ++ V + D D+G YTC A
Sbjct: 2127 -SDAIPPPTLTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAGKTEK 2185
Query: 622 SAVLSVVDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQ 681
+ +++ PN ELT L + + P I + + + P L
Sbjct: 2186 NYNVNIWVPPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGS---PVLTDSM 2242
Query: 682 TEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLG 741
V QL++S + + + ++ A ++Y + PT + G
Sbjct: 2243 GRVRILSGGRQLQIS--IAEKSDAALYSCVASNVAGTAKKEYNLQVY---IRPT-ITNSG 2296
Query: 742 SEPDNLVITWKPLNGFESNGPGLQYKVSWRQKDGD-----------DEWTSVVVANVSKY 790
S P +++T E G+ KDG DE + + N+
Sbjct: 2297 SHPTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHILQLKNIH-- 2354
Query: 791 IVSGTPTFVPYLIKVQALNDMGF-----APEPAVVMGHSGEDLPMVAPGNVRVNVVNSTL 845
VS T +V + V + D + AP P+++ H +P N+ V NS
Sbjct: 2355 -VSDTGRYVCVAVNVAGMTDKKYDLSVHAP-PSIIGNHR-------SPENISVVEKNSVS 2405
Query: 846 AEVHWDPVPLKSIRGHLQGYRI 867
+PL SI G+ +
Sbjct: 2406 LTCEASGIPLPSITWFKDGWPV 2427
Score = 144 bits (362), Expect = 6e-34
Identities = 160/631 (25%), Positives = 237/631 (37%), Gaps = 77/631 (12%)
Query: 42 ITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIIN 101
++Q P + + E + + CE K PPP +W + T P T P I
Sbjct: 1081 LSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKE-TQLISPFSPRHTFLPSGSMKITE 1139
Query: 102 IMSEGKAETYEGVYQCTARNERG---AAVSNNIVVRP--SRSPLWTKEKLEPITLQSGQS 156
+ G+Y C A N G AV N+ V P R P + + +Q GQ
Sbjct: 1140 TRTSD-----SGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGP-------KHLKVQVGQR 1187
Query: 157 LVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARF 216
+ +PC G P P+I W L E +G L P D Y C
Sbjct: 1188 VDIPCNAQ-GTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDA-GIYTC---- 1241
Query: 217 NHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTF--LTPEGNASNK 274
+A N++ T+ + PPT L P N + +
Sbjct: 1242 -------------------------VATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQ 1276
Query: 275 EELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFE--KTLQIIHVSEADSGNY 332
E + + C A+G P P I W L E L I V+ D+G Y
Sbjct: 1277 ERVANQRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEY 1336
Query: 333 QCIAKNALGAIHHTISVRVKAAPYWITAPQ--NLVLSPGEDGTLICRANGNPKPRISWLT 390
C+A N G +++V P Q N+ + + L C G P P I W
Sbjct: 1337 ICVAVNEAGTTERKYNLKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYK 1396
Query: 391 NGVPIEIAPDDPSRKIDGDTII-FSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPR 449
+ V ++ + ++ I+ + Y C A N G ++VL P
Sbjct: 1397 DNV--QVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTI 1454
Query: 450 ILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHE-DIYVLHENGTLEIPV 508
I T V+ NR L+C G+P P I WFK K L + ++ +L L +
Sbjct: 1455 IGTNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKN 1514
Query: 509 AQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIV--KQPEYAVVQRGSMVSFECKVKHD 566
A+++ G Y C N G ++ L I P I V S++ EC+ +
Sbjct: 1515 ARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGL 1574
Query: 567 HTLSLTVLWLKDNRE-LPSDERFTVDKD---HLVVADVSDDDSGTYTC-VANTTLDSVSA 621
++T W KD + + S + +DK H+ A VS DS TYTC VAN V+
Sbjct: 1575 PMPAIT--WYKDGQPIMSSSQALYIDKGQYLHIPRAQVS--DSATYTCHVAN-----VAG 1625
Query: 622 SAVLSV-VDVPNPP-FDLELTDQLDKSVQLS 650
+A S VDV PP + L L+K V ++
Sbjct: 1626 TAEKSFHVDVYVPPMIEGNLATPLNKQVVIA 1656
Score = 144 bits (362), Expect = 6e-34
Identities = 150/613 (24%), Positives = 247/613 (40%), Gaps = 79/613 (12%)
Query: 34 LDLVQPPTI----TQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLV 89
L++ PTI + +P+D + + CEA PP + +W ++GT + +++ +
Sbjct: 2565 LNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRN--I 2622
Query: 90 TMKPGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSN---NIVVRP--SRSPLWTKE 144
+ PG TL I E A G Y C A NE G + + + + P ++ LW
Sbjct: 2623 RILPGGRTLQILNAQEDNA----GRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPG 2678
Query: 145 KLEP--ITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVL 202
L P + ++ +L L C +P + W + Q L + V+ NG
Sbjct: 2679 -LSPKEVKIKVNNTLTLECEA-YAIPSASLSWYKDG-QPLKSDDHVNIAANG-------- 2727
Query: 203 PEDTREDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPP 262
HT I++ Q IS +A+N++ + + + PP
Sbjct: 2728 ---------------HTLQIKEAQ------ISDTGRYTCVASNIAGEDELDFDVNIQVPP 2766
Query: 263 TF---------LTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKN-RTVY 312
+F L N K+ + N +SL C P P + W K+ L + + +
Sbjct: 2767 SFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLI 2826
Query: 313 KNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITA----PQNLVLSP 368
+ LQI D+G Y C+A N G VRV P A P+ + +
Sbjct: 2827 LPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRVLVPPIIKGANSDLPEEVTVLV 2886
Query: 369 GEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTII-FSNVQERSSAVYQCN 427
+ + C ++G+P PR SW +G P+ DD + + I+ N Q Y C
Sbjct: 2887 NKSALIECLSSGSPAPRNSWQKDGQPL--LEDDHHKFLSNGRILQILNTQITDIGRYVCV 2944
Query: 428 ASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAK 487
A N G +NV PP ++ P + V+ N L C G P P + W K +
Sbjct: 2945 AENTAGSAKKYFNLNVHV-PPSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQ 3003
Query: 488 GSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPE 547
L+ + ++ TL+I A+ G YTC+A N+ G +K + L + P I
Sbjct: 3004 PIKLNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDS 3063
Query: 548 YAV----VQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKD----HLVVAD 599
++ V+ G+ VS EC + + + W K+ R + + D H+ A+
Sbjct: 3064 ESLSVVNVREGTSVSLEC--ESNAVPPPVITWYKNGRMITESTHVEILADGQMLHIKKAE 3121
Query: 600 VSDDDSGTYTCVA 612
VS D+G Y C A
Sbjct: 3122 VS--DTGQYVCRA 3132
Score = 143 bits (360), Expect = 1e-33
Identities = 150/608 (24%), Positives = 235/608 (38%), Gaps = 64/608 (10%)
Query: 32 VPLDLVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTM 91
V L + PP+I + P D+++ VI C A G P PS WT+NG +
Sbjct: 3889 VDLTVQVPPSIADE-PTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRL---------L 3938
Query: 92 KPGTGTLIINIMSEGKAE------TYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEK 145
G G I+S G E + G Y C ARN G+A ++ + P+ +
Sbjct: 3939 PRGDG---YRILSSGAIEILATQLNHAGRYTCVARNAAGSA-HRHVTLHVHEPPVIQPQP 3994
Query: 146 LEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPED 205
E + + ++LPC G P P I W + +G L S + ED
Sbjct: 3995 SE-LHVILNNPILLPCEAT-GTPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVRED 4052
Query: 206 TREDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFL 265
Y+C A+ N T K ++V+V V I+ +L + + ++P
Sbjct: 4053 AGT-YMCVAQ-NPAGTALGKIKLNVQVPPV------ISPHLKEYVI-----AVDKP---- 4095
Query: 266 TPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVS 325
++L C A+GLP P I W K+ + ++ +LQI V
Sbjct: 4096 ----------------ITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQIAFVQ 4139
Query: 326 EADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPR 385
D+G+Y C+A N G+ + + V P + + ++ L C A+G P P
Sbjct: 4140 PGDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPA 4199
Query: 386 ISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLA 445
I+W + V + + + G+ +I NV S Y C A+N G + V
Sbjct: 4200 INWKKDNVLLANLLGKYTAEPYGE-LILENVVLEDSGFYTCVANNAAGEDTHTVSLTVHV 4258
Query: 446 EPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLE 505
P P + + L C G PLP + W H D H L
Sbjct: 4259 LPTFTELPGDV--SLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFDSVNGHSE--LV 4314
Query: 506 IPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDP-TWIVKQPEYAVVQRGSMVSFECKVK 564
I K+ +GTY C A N +G K + +K+P + P + G C+VK
Sbjct: 4315 IERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPLGGNAILNCEVK 4374
Query: 565 HDHTLSLTVLWLKDNRELPSDERFT-VDKDHLVVADVSDDDSGTYTCVANTTLDSVSASA 623
D T T+ W + ++ R + L + ++D+G YTCVA V S
Sbjct: 4375 GDPTP--TIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSM 4432
Query: 624 VLSVVDVP 631
L++ P
Sbjct: 4433 SLTLQSPP 4440
Score = 142 bits (358), Expect = 2e-33
Identities = 168/711 (23%), Positives = 269/711 (37%), Gaps = 107/711 (15%)
Query: 8 KKKRLSAGRVPLILFLCQMISA-----LEVPLDLVQPPTITQQSPKDYIIDPRENIV-IQ 61
K + +SA + ++C S ++ +D++ PP I Y I N++ +
Sbjct: 1696 KLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELD 1755
Query: 62 CEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQCTARN 121
C G PPP+ W ++G D ++D + G +I G+Y+C A N
Sbjct: 1756 CHVTGSPPPTIMWLKDGQLID-ERDGFKILLNGRKLVIAQAQVSN-----TGLYRCMAAN 1809
Query: 122 ERG---AAVSNNIVVRPSRSPLWTKE----KLEPITLQSGQSLVLPCRPPIGLPPPIIFW 174
G + V P+ E K +P+ LQ + G+P P I W
Sbjct: 1810 TAGDHKKEFEVTVHVPPTIKSSGLSERVVVKYKPVALQCIAN---------GIPNPSITW 1860
Query: 175 M-DNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYA------RFNHTQ------- 220
+ D+ Q Q L + L ED Y C A H Q
Sbjct: 1861 LKDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGR-YTCVATNAAGETQQHIQLHVHEPP 1919
Query: 221 -----------TIQQKQPI---------------------------SVKVISVDELNDTI 242
T+ P+ S+ ++ ++ D
Sbjct: 1920 SLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIE 1979
Query: 243 AANLSDTEFY--------GAKSSRERPPTFLTPEGNASNK--EELRGNVLSLECIAEGLP 292
+A +SD Y GA + P + SN + N + LEC A G+P
Sbjct: 1980 SAQISDAGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPVRLECEARGIP 2039
Query: 293 TPIIYWAKEDGMLP--KNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVR 350
P + W K+ + N + + L + +D+G Y C+A NA G I +R
Sbjct: 2040 APSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLR 2099
Query: 351 VKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDT 410
V P + QN+ + + L+C+++ P P ++WL +G P+ P S +
Sbjct: 2100 VYVPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKP-GLSISENRSV 2158
Query: 411 IIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIANRPALLDC 470
+ + Q + + Y C A+N G N VN+ P + T VI L C
Sbjct: 2159 LKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGSDELTQLTVIEGNLISLLC 2218
Query: 471 AFFGSPLPTIEWFKGAKGSALHED----IYVLHENGTLEIPVAQKDSTGTYTCVARNKLG 526
G P P + W K KGS + D + +L L+I +A+K Y+CVA N G
Sbjct: 2219 ESSGIPPPNLIWKK--KGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAG 2276
Query: 527 MAKNEVHLEIKDPTWIV---KQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELP 583
AK E +L++ I P +V RG +S EC+V+ TV W+KD L
Sbjct: 2277 TAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQ--GIPPPTVTWMKDGHPLI 2334
Query: 584 SDERFTV-DKDHLV-VADVSDDDSGTYTCVANTTLDSVSASAVLSVVDVPN 632
+ + D+ H++ + ++ D+G Y CVA LSV P+
Sbjct: 2335 KAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPS 2385
Score = 137 bits (344), Expect = 8e-32
Identities = 147/596 (24%), Positives = 235/596 (39%), Gaps = 67/596 (11%)
Query: 58 IVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQC 117
+ + C+A G P PS W++ G G+ + ++S G E+ G Y C
Sbjct: 998 VTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGS----LYVVSPGGEES--GEYVC 1051
Query: 118 TARNERGAA---VSNNIVVRP---SRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPI 171
TA N G A V + VRP +++K I++ +G+ + LPC LPPPI
Sbjct: 1052 TATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVK-SLPPPI 1110
Query: 172 IFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVK 231
I W + P S R + +G + + D+ Y+C
Sbjct: 1111 ITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGM-YLC------------------- 1150
Query: 232 VISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGL 291
+A N++ K + PP G K ++ G + + C A+G
Sbjct: 1151 ----------VATNIAGNVTQAVKLNVHVPPKI--QRGPKHLKVQV-GQRVDIPCNAQGT 1197
Query: 292 PTPIIYWAKEDG-MLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVR 350
P P+I W+K ML N + TL I + +D+G Y C+A N G I++
Sbjct: 1198 PLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIAGTDETEITLH 1257
Query: 351 VKAAPYW--ITAPQNLVLSPGEDGTLI---CRANGNPKPRISWLTNGVPIEIAPDDPSRK 405
V+ P + P N I C A G PKP I WL NG E+ +P
Sbjct: 1258 VQEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNG--RELTGREPGIS 1315
Query: 406 I--DGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIAN 463
I DG ++ ++V + Y C A NE G + V P T V+ N
Sbjct: 1316 ILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKDKEQVTNVSVLLN 1375
Query: 464 RPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARN 523
+ L C G+P P I W+K I ++ L++ A + G Y+C A N
Sbjct: 1376 QLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAIN 1435
Query: 524 KLGMAKNEVHLEIKDPTWIV--KQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRE 581
G ++ ++++ P I+ P V V+ EC+VK T + W KD +
Sbjct: 1436 IAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALECQVK--GTPFPDIHWFKDGKP 1493
Query: 582 L----PSDERFTVDKDHLV-VADVSDDDSGTYTCVANTTLDSVSASAVLSVVDVPN 632
L P+ E +D+ ++ + + +D G Y C + + L++ P+
Sbjct: 1494 LFLGDPNVE--LLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPS 1547
Score = 136 bits (342), Expect = 1e-31
Identities = 143/603 (23%), Positives = 227/603 (37%), Gaps = 80/603 (13%)
Query: 34 LDLVQPPTIT-QQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMK 92
L + PP++ + P D + EN+ + C A G P P W ++G + + +
Sbjct: 3239 LSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVS 3298
Query: 93 PGTGTLIINIMSEGKAETYEGVYQCTARNERGAA---VSNNIVVRPSRSPLWTKEKLEPI 149
TL NI ++T G Y C A N G + N+ V P+ K++ E +
Sbjct: 3299 ANGSTL--NIYGALTSDT--GKYTCVATNPAGEEDRIFNLNVYVTPTIRG--NKDEAEKL 3352
Query: 150 TLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTRED 209
S+ + CR G PPP I W+ N LP S +
Sbjct: 3353 MTLVDTSINIECRAT-GTPPPQINWLKNGLP-LPLSSHI--------------------- 3389
Query: 210 YICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFY--------GAKSSRERP 261
++++ ++ + A +SD Y G +
Sbjct: 3390 ---------------------RLLAAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNL 3428
Query: 262 PTFLTPE-GNASNKEE---LRGNVLSLECIAEGLPTPIIYWAKEDGMLPKN-RTVYKNFE 316
F P N+ EE L+G+ S+ CI +G P P + W ++ L +
Sbjct: 3429 QVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHG 3488
Query: 317 KTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQN-----LVLSPGED 371
LQ++ DSG Y CIA N G + ++V P+ + ++ +V +P E
Sbjct: 3489 MVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEEISVIVNNPLE- 3547
Query: 372 GTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNE 431
L C A+G P P+++W+ +G P+ D G+ + S Q + Y C AS+
Sbjct: 3548 --LTCIASGIPAPKMTWMKDGRPLP-QTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSP 3604
Query: 432 YGYLLANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSAL 491
G V V P T V+ NR L+C P P I W + +
Sbjct: 3605 AGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQA 3664
Query: 492 HEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVV 551
+ +L L+I A T YTCVA N G E L + P I P+ V+
Sbjct: 3665 TPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVI 3724
Query: 552 QRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDE-RFTV-DKDHLVVADVSDDDSGTYT 609
EC + T +T W KD L + R+++ + L + D+G Y
Sbjct: 3725 LLNKSTVLECIAEGVPTPRIT--WRKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYL 3782
Query: 610 CVA 612
C+A
Sbjct: 3783 CMA 3785
Score = 135 bits (341), Expect = 2e-31
Identities = 138/586 (23%), Positives = 237/586 (40%), Gaps = 59/586 (10%)
Query: 60 IQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQCTA 119
++CEA+G P PS +W ++G+ + L + G I+ + S ++T G Y C A
Sbjct: 2031 LECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGR---ILALTSAQISDT--GRYTCVA 2085
Query: 120 RNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSF 179
N G +I +R P E+ + +++ Q++ L C+ +PPP + W+ +
Sbjct: 2086 VNAAGEK-QRDIDLRVYVPPNIMGEE-QNVSVLISQAVELLCQSD-AIPPPTLTWLKDGH 2142
Query: 180 QRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELN 239
L + L + +DT Y C A ++ K +N
Sbjct: 2143 PLLKKPGLSISENRSVLKIEDAQVQDTGR-YTCEAT-----------NVAGKTEKNYNVN 2190
Query: 240 DTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWA 299
+ N+ ++ + + GN++SL C + G+P P + W
Sbjct: 2191 IWVPPNIGGSD-------------------ELTQLTVIEGNLISLLCESSGIPPPNLIWK 2231
Query: 300 KEDGML---PKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPY 356
K+ + R + + LQI ++D+ Y C+A N G +++V P
Sbjct: 2232 KKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRPT 2291
Query: 357 WITA---PQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIF 413
+ P ++++ G+ +L C G P P ++W+ +G P+ I +G +
Sbjct: 2292 ITNSGSHPTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPL-IKAKGVEILDEGHILQL 2350
Query: 414 SNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRIL----TPANTLYQVIANRPALLD 469
N+ + Y C A N G ++V A PP I+ +P N V+ L
Sbjct: 2351 KNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHA-PPSIIGNHRSPENI--SVVEKNSVSLT 2407
Query: 470 CAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAK 529
C G PLP+I WFK +L + +L L + + G YTCV RN G +
Sbjct: 2408 CEASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAGEER 2467
Query: 530 NEVHLEIKDPTWIVKQP--EYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDER 587
L + P IV + E V+ V+ C+V + +T W KD + L DE
Sbjct: 2468 KIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEIT--WHKDGQPLQEDEA 2525
Query: 588 FTVDKD--HLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVDVP 631
+ L + +V +G YTC+A++ S S L+V P
Sbjct: 2526 HHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSP 2571
Score = 127 bits (319), Expect = 6e-29
Identities = 148/626 (23%), Positives = 244/626 (38%), Gaps = 100/626 (15%)
Query: 31 EVPLDLVQPPTITQQS--PKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPL 88
E L + PTIT P + I+ ++I ++CE +G PPP+ +W ++G PL
Sbjct: 2281 EYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPPTVTWMKDG-------HPL 2333
Query: 89 VTMKPGTGTLIINIMSEGKAETYE-------GVYQCTARNERGAAVSN-NIVVRPSRSPL 140
+ K + I+ EG + G Y C A N G ++ V S +
Sbjct: 2334 IKAKG------VEILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSII 2387
Query: 141 WTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQ-RLPQSERVSQGLNGDLYFS 199
E I++ S+ L C G+P P I W + + L S R+ G L
Sbjct: 2388 GNHRSPENISVVEKNSVSLTCEAS-GIPLPSITWFKDGWPVSLSNSVRILSG-GRMLRLM 2445
Query: 200 NVLPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRE 259
ED + Y C R ++++ + V+
Sbjct: 2446 QTTMEDAGQ-YTCVVR---NAAGEERKIFGLSVL-------------------------- 2475
Query: 260 RPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVY-KNFEKT 318
P + E + + ++L C G P P I W K+ L ++ + + +
Sbjct: 2476 -VPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRF 2534
Query: 319 LQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITA-----PQNLVLSPGEDGT 373
LQI +V +G Y C+A + G + S+ V +P P+++ + +
Sbjct: 2535 LQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTS 2594
Query: 374 LICRANGNPKPRISWLTNGVPIEIAPDDPSRKI----DGDTIIFSNVQERSSAVYQCNAS 429
L+C A P I+W +G P+E +R I G T+ N QE ++ Y C A+
Sbjct: 2595 LVCEAYSYPPATITWFKDGTPLE-----SNRNIRILPGGRTLQILNAQEDNAGRYSCVAT 2649
Query: 430 NEYGYLLANAFVNVLAEPPRI---------LTPANTLYQVIANRPALLDCAFFGSPLPTI 480
NE G ++ + V V PP I L+P +V N L+C + P ++
Sbjct: 2650 NEAGEMIKHYEVKVYI-PPIINKGDLWGPGLSPKEVKIKV--NNTLTLECEAYAIPSASL 2706
Query: 481 EWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDP- 539
W+K + + + + TL+I AQ TG YTCVA N G + + + I+ P
Sbjct: 2707 SWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQVPP 2766
Query: 540 ----TWIV-------KQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERF 588
W + + E V + +S C+ +LT W KD L S ++
Sbjct: 2767 SFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLT--WYKDGHPLTSSDKV 2824
Query: 589 TV--DKDHLVVADVSDDDSGTYTCVA 612
+ L + +D+G YTCVA
Sbjct: 2825 LILPGGRVLQIPRAKVEDAGRYTCVA 2850
Score = 126 bits (316), Expect = 1e-28
Identities = 105/365 (28%), Positives = 157/365 (43%), Gaps = 13/365 (3%)
Query: 277 LRGNVLSLECIAEGLPTPIIYWAKE-DGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCI 335
L +++ LEC GLP P I W K+ ++ ++ +Y + + L I +DS Y C
Sbjct: 1560 LINSLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCH 1619
Query: 336 AKNALGAIHHTISVRVKAAPYW---ITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNG 392
N G + V V P + P N + TL C+A GNP P ++WL +G
Sbjct: 1620 VANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLKDG 1679
Query: 393 VPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILT 452
VP++ A D+ + G + + QE Y C A++ G V+VL PP I
Sbjct: 1680 VPVK-ANDNIRIEAGGKKLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLV-PPAIEG 1737
Query: 453 PANTLYQVI-ANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQK 511
T Y ++ N LDC GSP PTI W K + + +L L I AQ
Sbjct: 1738 GDETSYFIVMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQV 1797
Query: 512 DSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQP-EYAVVQRGSMVSFECKVKHDHTLS 570
+TG Y C+A N G K E + + P I VV + V+ +C S
Sbjct: 1798 SNTGLYRCMAANTAGDHKKEFEVTVHVPPTIKSSGLSERVVVKYKPVALQCIANGIPNPS 1857
Query: 571 LTVLWLKDNRELPSDE---RFTVDKDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSV 627
+T WLKD++ + + + + L +A +D+G YTCVA L V
Sbjct: 1858 IT--WLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHV 1915
Query: 628 VDVPN 632
+ P+
Sbjct: 1916 HEPPS 1920
Score = 122 bits (306), Expect = 2e-27
Identities = 156/639 (24%), Positives = 241/639 (37%), Gaps = 77/639 (12%)
Query: 25 QMISALEVPLDLVQPPTITQQ-------SPKDYIIDPRENIVIQCEAKGKPPPSFSWTRN 77
+MI EV + + PP I + SPK+ I + ++CEA P S SW ++
Sbjct: 2654 EMIKHYEVKVYI--PPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKD 2711
Query: 78 GTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSN---NIVVR 134
G D + T + I ++T G Y C A N G + NI V
Sbjct: 2712 GQPLKSDDHVNIAANGHT----LQIKEAQISDT--GRYTCVASNIAGEDELDFDVNIQVP 2765
Query: 135 PSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGL-------PPPIIFWMDNSFQRLPQSER 187
PS LW + T ++G++ + PI L PPP + W + L S++
Sbjct: 2766 PSFQKLWEIGNMLD-TGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGHP-LTSSDK 2823
Query: 188 VSQGLNGDLYFSNVLPEDTRED---YICYARFNHTQTIQQKQPISVKVISVDELNDTIAA 244
V G + +P ED Y C ++V D L +
Sbjct: 2824 VLILPGGRVL---QIPRAKVEDAGRYTC---------------VAVNEAGEDSLQYDVRV 2865
Query: 245 NLSDTEFYGAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKE-DG 303
L GA S T L NK L +EC++ G P P W K+
Sbjct: 2866 -LVPPIIKGANSDLPEEVTVLV------NKSAL------IECLSSGSPAPRNSWQKDGQP 2912
Query: 304 MLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWI-TAPQ 362
+L + + + + LQI++ D G Y C+A+N G+ ++ V P I +
Sbjct: 2913 LLEDDHHKFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPKSE 2972
Query: 363 NLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSA 422
NL + +L C +G P P +SWL N PI++ + G T+ +
Sbjct: 2973 NLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVP-GGRTLQIIRAKVSDGG 3031
Query: 423 VYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIANRPAL---LDCAFFGSPLPT 479
Y C A N+ G + V PP I + V+ R L+C P P
Sbjct: 3032 EYTCIAINQAGESKKKFSLTVYV-PPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPV 3090
Query: 480 IEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDP 539
I W+K + + +L + L I A+ TG Y C A N G HL + P
Sbjct: 3091 ITWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVP 3150
Query: 540 TWIVKQPEYAVVQR--GSMVSFECKVKHDHTLSLTVLWLKDNRELPSDE----RFTVDKD 593
++ PE V+ + V+ C T+ WLK+++ + + + R
Sbjct: 3151 P-SIEGPEREVIVETISNPVTLTCDA--TGIPPPTIAWLKNHKRIENSDSLEVRILSGGS 3207
Query: 594 HLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVDVPN 632
L +A DSG YTC+A+ LS+ P+
Sbjct: 3208 KLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSIQVPPS 3246
Score = 116 bits (290), Expect = 1e-25
Identities = 138/601 (22%), Positives = 224/601 (37%), Gaps = 85/601 (14%)
Query: 58 IVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQC 117
+ ++C+A G P P +W ++ + + G II+I S ++ G+Y+C
Sbjct: 1938 VQLECKAAGNPVPVITWYKDNRLLS-GSTSMTFLNRGQ---IIDIESAQISDA--GIYKC 1991
Query: 118 TARNERGAA---VSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFW 174
A N GA S + V PS S + + + + L R G+P P + W
Sbjct: 1992 VAINSAGATELFYSLQVHVAPSISG---SNNMVAVVVNNPVRLECEAR---GIPAPSLTW 2045
Query: 175 MDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVIS 234
L VS NG ++V+S
Sbjct: 2046 -------LKDGSPVSSFSNG-----------------------------------LQVLS 2063
Query: 235 VDELNDTIAANLSDTEFY-----GAKSSRER--------PPTFLTPEGNASNKEELRGNV 281
+ +A +SDT Y A ++R PP + E N S L
Sbjct: 2064 GGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVS---VLISQA 2120
Query: 282 LSLECIAEGLPTPIIYWAKEDG-MLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNAL 340
+ L C ++ +P P + W K+ +L K L+I D+G Y C A N
Sbjct: 2121 VELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVA 2180
Query: 341 GAIHHTISVRVKAAPYWITAPQ--NLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIA 398
G +V + P + + L + G +L+C ++G P P + W G P+
Sbjct: 2181 GKTEKNYNVNIWVPPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTD 2240
Query: 399 PDDPSRKIDGDTIIFSNVQERS-SAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTL 457
R + G + ++ E+S +A+Y C ASN G + V P + ++
Sbjct: 2241 SMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPT 2300
Query: 458 YQVIANRPAL-LDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGT 516
++ ++ L+C G P PT+ W K + + +L E L++ TG
Sbjct: 2301 EIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGR 2360
Query: 517 YTCVARNKLGMAKNEVHLEIKDPTWIV---KQPEYAVVQRGSMVSFECKVKHDHTLSLTV 573
Y CVA N GM + L + P I+ + PE V + VS C+ S+T
Sbjct: 2361 YVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSIT- 2419
Query: 574 LWLKDNR--ELPSDERFTVDKDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVDVP 631
W KD L + R L + + +D+G YTCV LSV+ P
Sbjct: 2420 -WFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPP 2478
Query: 632 N 632
+
Sbjct: 2479 H 2479
Score = 111 bits (277), Expect = 5e-24
Identities = 91/384 (23%), Positives = 159/384 (41%), Gaps = 20/384 (5%)
Query: 259 ERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDG--MLPKNRTVYKNFE 316
E PP P +N G L C+ + W + D L + +
Sbjct: 518 EPPPVIQVP----NNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLAN 573
Query: 317 KTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLIC 376
+L++ V D+G Y C+ + G+ ++ + V+ P P+N + G + +++C
Sbjct: 574 LSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGGSEVSIMC 633
Query: 377 RANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLL 436
A G PKP+I+W N + I R T+ N + + +Y C ASN G
Sbjct: 634 SATGYPKPKIAWTVN--DMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNSAGTDK 691
Query: 437 ANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIY 496
N+ + + P ++ + L V +++C G P P ++WFKG +
Sbjct: 692 QNSTLRYIEAPKLMVVQSELL--VALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLI 749
Query: 497 VLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSM 556
+ G L+I Q G YTCVA N+ G A ++ L++ P +++P ++ GS
Sbjct: 750 IDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPADVSMEIGSN 809
Query: 557 VSFECKVKHDHTLSLTVLWLK-DNRELPSDERFTVDK------DHLVVADVSDDDSGTYT 609
V+ C V+ T+ W + DN + S F+V L + ++ D GTY
Sbjct: 810 VTLPCYVQ--GYPEPTIKWRRLDNMPIFS-RPFSVSSISQLRTGALFILNLWASDKGTYI 866
Query: 610 CVANTTLDSVSASAVLSVVDVPNP 633
C A + + ++V + P
Sbjct: 867 CEAENQFGKIQSETTVTVTGLVAP 890
Score = 108 bits (270), Expect = 3e-23
Identities = 134/604 (22%), Positives = 229/604 (37%), Gaps = 65/604 (10%)
Query: 22 FLCQMISALEVPLDLVQPPTITQ-QSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTH 80
+L Q +S++ + P +T + Y + P + I C P + S+ RNG
Sbjct: 413 YLFQRVSSVSFSSIVPDAPKVTMPEKTPGYYLQPGQ---IPCSVDSLLPFTLSFVRNGVT 469
Query: 81 FDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPL 140
+D+ +K +N+ + EG Y+C A + G + P+
Sbjct: 470 LGVDQ----YLKESAS---VNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPV 522
Query: 141 WTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSN 200
+ +T+ G+ VL C + + + ++ RL + R+ N L +
Sbjct: 523 I--QVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLELKS 580
Query: 201 VLPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRER 260
V D E Y C V + AA++ T +E
Sbjct: 581 VKFNDAGE-YHCM---------------------VSSEGGSSAASVFLTV-------QEP 611
Query: 261 PPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQ 320
P + P+ N+ G+ +S+ C A G P P I W D + + + TL
Sbjct: 612 PKVTVMPK----NQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLF 667
Query: 321 IIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANG 380
I + + D+G Y C+A N+ G ++R AP + L+++ G+ + C+ +G
Sbjct: 668 IKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTSG 727
Query: 381 NPKPRISWLTNGVPIEIAPDDPSRKIDGDTII----FSNVQERSSAVYQCNASNEYGYLL 436
P P++ W + + PS + D ++ Q+ + Y C A NE G
Sbjct: 728 IPPPQVKWFKGDLELR-----PSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRAT 782
Query: 437 ANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIY 496
++V + P I PA+ ++ +N L C G P PTI+W +
Sbjct: 783 GKITLDVGSPPVFIQEPADVSMEIGSN--VTLPCYVQGYPEPTIKWRRLDNMPIFSRPFS 840
Query: 497 VLH----ENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKD--PTWIVKQPEYAV 550
V G L I GTY C A N+ G ++E + + I P A
Sbjct: 841 VSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVAN 900
Query: 551 VQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKD-HLVVADVSDDDSGTYT 609
V G ++ C + + + W+K++ L + TV D L + V D G YT
Sbjct: 901 VIEGQQLTLPCTLLAGNPIP-ERRWIKNSAMLLQNPYITVRSDGSLHIERVQLQDGGEYT 959
Query: 610 CVAN 613
CVA+
Sbjct: 960 CVAS 963
Score = 96.3 bits (238), Expect = 2e-19
Identities = 87/320 (27%), Positives = 132/320 (41%), Gaps = 14/320 (4%)
Query: 319 LQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRA 378
L I V+ +D G Y+CIA ++ G V P I P N+ ++PGE L C
Sbjct: 484 LDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVIQVPNNVTVTPGERAVLTCLI 543
Query: 379 NGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLAN 438
++W N + +A R + ++ +V+ + Y C S+E G A+
Sbjct: 544 ISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMVSSEGGSSAAS 603
Query: 439 AFVNVLAEPPRI-LTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYV 497
F+ V EPP++ + P N + + C+ G P P I W + Y
Sbjct: 604 VFLTV-QEPPKVTVMPKNQSF--TGGSEVSIMCSATGYPKPKIAWTVNDM-FIVGSHRYR 659
Query: 498 LHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLE-IKDPTWIVKQPEYAVVQRGSM 556
+ +GTL I A G Y C+A N G K L I+ P +V Q E +V G +
Sbjct: 660 MTSDGTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSE-LLVALGDI 718
Query: 557 VSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDK--DHLVVADVSDDDSGTYTCVANT 614
ECK V W K + EL +D L + + D D+G YTCVA
Sbjct: 719 TVMECKT--SGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVA-- 774
Query: 615 TLDSVSASAVLSVVDVPNPP 634
++ + +DV +PP
Sbjct: 775 -INEAGRATGKITLDVGSPP 793
Score = 96.3 bits (238), Expect = 2e-19
Identities = 98/421 (23%), Positives = 175/421 (41%), Gaps = 56/421 (13%)
Query: 28 SALEVPLDLVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDP 87
S+ L + PP I + + Y ++ ++ C A G P P+ +W ++ +
Sbjct: 4157 SSTSTKLTVHVPPRI-RSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLL-ANLLG 4214
Query: 88 LVTMKPGTGTLIINIMSEGKAETYEGVYQCTARNERGA---AVSNNIVVRPSRSPLWTKE 144
T +P ++ N++ E G Y C A N G VS + V P+ + L
Sbjct: 4215 KYTAEPYGELILENVVLEDS-----GFYTCVANNAAGEDTHTVSLTVHVLPTFTEL---- 4265
Query: 145 KLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPE 204
++L G+ L L C+ G+P P + W N+ + + S + +L V E
Sbjct: 4266 -PGDVSLNKGEQLRLSCKAT-GIPLPKLTWTFNN--NIIPAHFDSVNGHSELVIERVSKE 4321
Query: 205 DTREDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTF 264
D+ Y+C A N ++ + VK PP F
Sbjct: 4322 DSGT-YVCTAE-NSVGFVKAIGFVYVK----------------------------EPPVF 4351
Query: 265 LTPEGNASNK--EELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQII 322
+G+ + E L GN + L C +G PTP I W ++ + + + + +L I
Sbjct: 4352 ---KGDYPSNWIEPLGGNAI-LNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIY 4407
Query: 323 HVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNP 382
D+G+Y C+A N G + ++S+ +++ P P V++ G L C+A G P
Sbjct: 4408 GTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITLEPVETVINAGGKIILNCQATGEP 4467
Query: 383 KPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVN 442
+P I+W G I+ DD + +++ ++ Q+ ++ ++C A N G +L V
Sbjct: 4468 QPTITWSRQG--HSISWDDRVNVLSNNSLYIADAQKEDTSEFECVARNLMGSVLVRVPVI 4525
Query: 443 V 443
V
Sbjct: 4526 V 4526
Score = 72.0 bits (175), Expect = 3e-12
Identities = 56/195 (28%), Positives = 87/195 (44%), Gaps = 13/195 (6%)
Query: 38 QPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGT 97
+PP P ++I N ++ CE KG P P+ W R G +I + G G+
Sbjct: 4347 EPPVFKGDYPSNWIEPLGGNAILNCEVKGDPTPTIQWNRKGVDIEISHR---IRQLGNGS 4403
Query: 98 LIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSL 157
L I G G Y C A NE G V ++ + P+ T E +E + + +G +
Sbjct: 4404 LAI----YGTVNEDAGDYTCVATNEAG-VVERSMSLTLQSPPIITLEPVETV-INAGGKI 4457
Query: 158 VLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFN 217
+L C+ G P P I W + +RV+ N LY ++ EDT E + C AR N
Sbjct: 4458 ILNCQ-ATGEPQPTITW-SRQGHSISWDDRVNVLSNNSLYIADAQKEDTSE-FECVAR-N 4513
Query: 218 HTQTIQQKQPISVKV 232
++ + P+ V+V
Sbjct: 4514 LMGSVLVRVPVIVQV 4528
Score = 66.2 bits (160), Expect = 2e-10
Identities = 75/323 (23%), Positives = 125/323 (38%), Gaps = 65/323 (20%)
Query: 40 PTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGT----HFDIDKDPLVTMKPGT 95
PT T+ P D ++ E + + C+A G P P +WT N HFD G
Sbjct: 4260 PTFTEL-PGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFDSVN--------GH 4310
Query: 96 GTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVV---RPSRSPLWTKEKLEPITLQ 152
L+I +S+ + G Y CTA N G + V P + +EP+
Sbjct: 4311 SELVIERVSKEDS----GTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPL--- 4363
Query: 153 SGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYIC 212
G + +L C G P P I W + S R+ Q NG L + ED DY C
Sbjct: 4364 -GGNAILNCEVK-GDPTPTIQWNRKGVD-IEISHRIRQLGNGSLAIYGTVNEDAG-DYTC 4419
Query: 213 YARFNHTQTIQQKQPISVK---VISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEG 269
A N +++ ++++ +I+++ + I A
Sbjct: 4420 VAT-NEAGVVERSMSLTLQSPPIITLEPVETVINA------------------------- 4453
Query: 270 NASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADS 329
G + L C A G P P I W+++ + + V +L I + D+
Sbjct: 4454 ---------GGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSNNSLYIADAQKEDT 4504
Query: 330 GNYQCIAKNALGAIHHTISVRVK 352
++C+A+N +G++ + V V+
Sbjct: 4505 SEFECVARNLMGSVLVRVPVIVQ 4527
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.133 0.398
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 51,029,252
Number of Sequences: 37866
Number of extensions: 2602749
Number of successful extensions: 15298
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 308
Number of HSP's successfully gapped in prelim test: 205
Number of HSP's that attempted gapping in prelim test: 5086
Number of HSP's gapped (non-prelim): 4704
length of query: 1183
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1070
effective length of database: 13,968,660
effective search space: 14946466200
effective search space used: 14946466200
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.