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Search of human proteins with 7706706
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7706706 sorting nexin 9 [Homo sapiens]
(595 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7706706 sorting nexin 9 [Homo sapiens] 1221 0.0
gi|157057545 sorting nexin 18 isoform a [Homo sapiens] 357 2e-98
gi|23397574 sorting nexin 33 [Homo sapiens] 355 5e-98
gi|224177511 sorting nexin 18 isoform c [Homo sapiens] 299 6e-81
gi|157057543 sorting nexin 18 isoform b [Homo sapiens] 299 6e-81
gi|153791707 sorting nexin family member 30 [Homo sapiens] 67 6e-11
gi|23111038 sorting nexin 2 [Homo sapiens] 59 2e-08
gi|23943858 sorting nexin 8 [Homo sapiens] 55 2e-07
gi|24797143 sorting nexin 14 isoform b [Homo sapiens] 50 4e-06
gi|24797145 sorting nexin 14 isoform a [Homo sapiens] 50 4e-06
gi|194294540 sorting nexin 7 isoform a [Homo sapiens] 49 1e-05
gi|67514036 SH3-domain kinase binding protein 1 isoform b [Homo ... 49 2e-05
gi|13994242 SH3-domain kinase binding protein 1 isoform a [Homo ... 49 2e-05
gi|155030230 sorbin and SH3 domain containing 3 isoform 1 [Homo ... 47 6e-05
gi|65301112 sorbin and SH3 domain containing 3 isoform 2 [Homo s... 47 6e-05
gi|23111055 sorting nexin 7 isoform b [Homo sapiens] 45 1e-04
gi|68348709 formin binding protein 1-like isoform 1 [Homo sapiens] 45 2e-04
gi|41581463 formin binding protein 1-like isoform 2 [Homo sapiens] 45 2e-04
gi|223468657 SH3-domain GRB2-like 3 [Homo sapiens] 44 5e-04
gi|41406080 growth arrest-specific 7 isoform c [Homo sapiens] 43 7e-04
gi|4506931 SH3-domain GRB2-like 2 [Homo sapiens] 43 7e-04
gi|222080100 BAI1-associated protein 2 isoform 4 [Homo sapiens] 43 0.001
gi|5453565 BAI1-associated protein 2 isoform 3 [Homo sapiens] 43 0.001
gi|9257197 BAI1-associated protein 2 isoform 1 [Homo sapiens] 43 0.001
gi|9257199 BAI1-associated protein 2 isoform 2 [Homo sapiens] 43 0.001
gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens] 43 0.001
gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens] 43 0.001
gi|23111026 sorting nexin 11 [Homo sapiens] 43 0.001
gi|23111028 sorting nexin 11 [Homo sapiens] 43 0.001
gi|4506929 SH3-domain GRB2-like 1 [Homo sapiens] 42 0.001
>gi|7706706 sorting nexin 9 [Homo sapiens]
Length = 595
Score = 1221 bits (3159), Expect = 0.0
Identities = 595/595 (100%), Positives = 595/595 (100%)
Query: 1 MATKARVMYDFAAEPGNNELTVNEGEIITITNPDVGGGWLEGRNIKGERGLVPTDYVEIL 60
MATKARVMYDFAAEPGNNELTVNEGEIITITNPDVGGGWLEGRNIKGERGLVPTDYVEIL
Sbjct: 1 MATKARVMYDFAAEPGNNELTVNEGEIITITNPDVGGGWLEGRNIKGERGLVPTDYVEIL 60
Query: 61 PSDGKDQFSCGNSVADQAFLDSLSASTAQASSSAASNNHQVGSGNDPWSAWSASKSGNWE 120
PSDGKDQFSCGNSVADQAFLDSLSASTAQASSSAASNNHQVGSGNDPWSAWSASKSGNWE
Sbjct: 61 PSDGKDQFSCGNSVADQAFLDSLSASTAQASSSAASNNHQVGSGNDPWSAWSASKSGNWE 120
Query: 121 SSEGWGAQPEGAGAQRNTNTPNNWDTAFGHPQAYQGPATGDDDDWDEDWDGPKSSSYFKD 180
SSEGWGAQPEGAGAQRNTNTPNNWDTAFGHPQAYQGPATGDDDDWDEDWDGPKSSSYFKD
Sbjct: 121 SSEGWGAQPEGAGAQRNTNTPNNWDTAFGHPQAYQGPATGDDDDWDEDWDGPKSSSYFKD 180
Query: 181 SESADAGGAQRGNSRASSSSMKIPLNKFPGFAKPGTEQYLLAKQLAKPKEKIPIIVGDYG 240
SESADAGGAQRGNSRASSSSMKIPLNKFPGFAKPGTEQYLLAKQLAKPKEKIPIIVGDYG
Sbjct: 181 SESADAGGAQRGNSRASSSSMKIPLNKFPGFAKPGTEQYLLAKQLAKPKEKIPIIVGDYG 240
Query: 241 PMWVYPTSTFDCVVADPRKGSKMYGLKSYIEYQLTPTNTNRSVNHRYKHFDWLYERLLVK 300
PMWVYPTSTFDCVVADPRKGSKMYGLKSYIEYQLTPTNTNRSVNHRYKHFDWLYERLLVK
Sbjct: 241 PMWVYPTSTFDCVVADPRKGSKMYGLKSYIEYQLTPTNTNRSVNHRYKHFDWLYERLLVK 300
Query: 301 FGSAIPIPSLPDKQVTGRFEEEFIKMRMERLQAWMTRMCRHPVISESEVFQQFLNFRDEK 360
FGSAIPIPSLPDKQVTGRFEEEFIKMRMERLQAWMTRMCRHPVISESEVFQQFLNFRDEK
Sbjct: 301 FGSAIPIPSLPDKQVTGRFEEEFIKMRMERLQAWMTRMCRHPVISESEVFQQFLNFRDEK 360
Query: 361 EWKTGKRKAERDELAGVMIFSTMEPEAPDLDLVEIEQKCEAVGKFTKAMDDGVKELLTVG 420
EWKTGKRKAERDELAGVMIFSTMEPEAPDLDLVEIEQKCEAVGKFTKAMDDGVKELLTVG
Sbjct: 361 EWKTGKRKAERDELAGVMIFSTMEPEAPDLDLVEIEQKCEAVGKFTKAMDDGVKELLTVG 420
Query: 421 QEHWKRCTGPLPKEYQKIGKALQSLATVFSSSGYQGETDLNDAITEAGKTYEEIASLVAE 480
QEHWKRCTGPLPKEYQKIGKALQSLATVFSSSGYQGETDLNDAITEAGKTYEEIASLVAE
Sbjct: 421 QEHWKRCTGPLPKEYQKIGKALQSLATVFSSSGYQGETDLNDAITEAGKTYEEIASLVAE 480
Query: 481 QPKKDLHFLMECNHEYKGFLGCFPDIIGTHKGAIEKVKESDKLVATSKITLQDKQNMVKR 540
QPKKDLHFLMECNHEYKGFLGCFPDIIGTHKGAIEKVKESDKLVATSKITLQDKQNMVKR
Sbjct: 481 QPKKDLHFLMECNHEYKGFLGCFPDIIGTHKGAIEKVKESDKLVATSKITLQDKQNMVKR 540
Query: 541 VSIMSYALQAEMNHFHSNRIYDYNSVIRLYLEQQVQFYETIAEKLRQALSRFPVM 595
VSIMSYALQAEMNHFHSNRIYDYNSVIRLYLEQQVQFYETIAEKLRQALSRFPVM
Sbjct: 541 VSIMSYALQAEMNHFHSNRIYDYNSVIRLYLEQQVQFYETIAEKLRQALSRFPVM 595
>gi|157057545 sorting nexin 18 isoform a [Homo sapiens]
Length = 624
Score = 357 bits (915), Expect = 2e-98
Identities = 228/637 (35%), Positives = 325/637 (51%), Gaps = 61/637 (9%)
Query: 1 MATKARVMYDFAAE-PGNNELTVNEGEIITITNPDVGGGWLEGRNIKGERGLVPTDYVEI 59
MA +AR +YDF +E PG E+++ E E++++ + GWLEG N +G+RGL P YV++
Sbjct: 1 MALRARALYDFRSENPG--EISLREHEVLSLCSEQDIEGWLEGVNSRGDRGLFPASYVQV 58
Query: 60 LPSDGKDQFSCGNSVADQAFLDSLSASTAQASSSAASNNHQVGSGNDPWSAWSASKSGNW 119
+ + G A + + + + S P A+ A
Sbjct: 59 IRAPEPGPAGDGGPGAPARYANVPPGGFEPLPVAPPA------SFKPPPDAFQALLQPQ- 111
Query: 120 ESSEGWGAQPEGAGAQRNTNTPNNWDTAFGHPQAYQG---PATGDDDDWDEDWD------ 170
++ QP GAG P PQ G + G DDDWD++WD
Sbjct: 112 QAPPPSTFQPPGAGF------PYGGGALQPSPQQLYGGYQASQGSDDDWDDEWDDSSTVA 165
Query: 171 ---GPKSSSYFKD---SESADAGGA--------------QRGNS---------RASSSSM 201
G S + D S SA G A RG S SS+++
Sbjct: 166 DEPGALGSGAYPDLDGSSSAGVGAAGRYRLSTRSDLSLGSRGGSVPPQHHPSGPKSSATV 225
Query: 202 KIPLNKFPGFAKPGTEQYLL--AKQLAKPKEKIPIIVGDYGPMWVYPTSTFDCVVADPRK 259
LN+F F K G E ++L A K +K+ +++G YGP W F C + DP K
Sbjct: 226 SRNLNRFSTFVKSGGEAFVLGEASGFVKDGDKLCVVLGPYGPEWQENPYPFQCTIDDPTK 285
Query: 260 GSKMYGLKSYIEYQLTPTNTNRSVNHRYKHFDWLYERLLVKFGSAIPIPSLPDKQVTGRF 319
+K G+KSYI Y+L PT+T V+ RYKHFDWLY RL KF I +P LP+KQ TGRF
Sbjct: 286 QTKFKGMKSYISYKLVPTHTQVPVHRRYKHFDWLYARLAEKF-PVISVPHLPEKQATGRF 344
Query: 320 EEEFIKMRMERLQAWMTRMCRHPVISESEVFQQFL---NFRDEKEWKTGKRKAERDELAG 376
EE+FI R + L WM M HPV+++ +VFQ FL + DEK WK GKRKAE+DE+ G
Sbjct: 345 EEDFISKRRKGLIWWMNHMASHPVLAQCDVFQHFLTCPSSTDEKAWKQGKRKAEKDEMVG 404
Query: 377 VMIFSTME-PEAPDLDLVEIEQKCEAVGKFTKAMDDGVKELLTVGQEHWKRCTGPLPKEY 435
F T+ P A LDL E+E K + FTK MDD +L E ++ KEY
Sbjct: 405 ANFFLTLSTPPAAALDLQEVESKIDGFKCFTKKMDDSALQLNHTANEFARKQVTGFKKEY 464
Query: 436 QKIGKALQSLATVFSSSGYQGETDLNDAITEAGKTYEEIASLVAEQPKKDLHFLMECNHE 495
QK+G++ + L+ F LN AI G Y+ I L AEQP++DL +M+
Sbjct: 465 QKVGQSFRGLSQAFELDQQAFSVGLNQAIAFTGDAYDAIGELFAEQPRQDLDPVMDLLAL 524
Query: 496 YKGFLGCFPDIIGTHKGAIEKVKESDKLVATSKITLQDKQNMVKRVSIMSYALQAEMNHF 555
Y+G L FPDII KGA+ KVKES + V K+ +Q + R + +S+A AE++HF
Sbjct: 525 YQGHLANFPDIIHVQKGALTKVKESRRHVEEGKMEVQKADGIQDRCNTISFATLAEIHHF 584
Query: 556 HSNRIYDYNSVIRLYLEQQVQFYETIAEKLRQALSRF 592
H R+ D+ S ++ +L+QQ+ F++ + +KL +AL ++
Sbjct: 585 HQIRVRDFKSQMQHFLQQQIIFFQKVTQKLEEALHKY 621
>gi|23397574 sorting nexin 33 [Homo sapiens]
Length = 574
Score = 355 bits (912), Expect = 5e-98
Identities = 213/601 (35%), Positives = 310/601 (51%), Gaps = 39/601 (6%)
Query: 1 MATKARVMYDFAAEPGNNELTVNEGEIITITNPDVGGGWLEGRNIKGERGLVPTDYVEIL 60
MA K R +YDF +E E+++ + E + I + GWL+G+N +GE GL P YVEI+
Sbjct: 1 MALKGRALYDFHSE-NKEEISIQQDEDLVIFSETSLDGWLQGQNSRGETGLFPASYVEIV 59
Query: 61 PSDGKDQFS------CGNSVADQAFLDSLS-ASTAQASSSAASNNHQVGSGNDPWSAWSA 113
S + G+ A + +S S AS A++ + ++Q D W
Sbjct: 60 RSGISTNHADYSSSPAGSPGAQVSLYNSPSVASPARSGGGSGFLSNQGSFEEDDDDDWD- 118
Query: 114 SKSGNWESSEGWGAQPEGAGAQRNTNTPNNWDTAFGHPQAYQGPATGDDDDWDEDWDGPK 173
+W+ +P G N + P N +P + PK
Sbjct: 119 ----DWDDGCTVVEEPRAGGLGTNGHPPLNLSYPGAYPSQHMAFR-------------PK 161
Query: 174 SSSYFKDSESADAGGAQRGNSRASSSSMKIPLNKFPGFAKPGTEQYLLAK--QLAKPKEK 231
+DS ++ G+ G + LN+F F + G E ++L +AK E
Sbjct: 162 PPLERQDSLASAKRGSVVGRN----------LNRFSCFVRSGVEAFILGDVPMMAKIAET 211
Query: 232 IPIIVGDYGPMWVYPTSTFDCVVADPRKGSKMYGLKSYIEYQLTPTNTNRSVNHRYKHFD 291
I +G GP W F C V DP K +K G+KSYI Y+LTPT+ V RYKHFD
Sbjct: 212 YSIEMGPRGPQWKANPHPFACSVEDPTKQTKFKGIKSYISYKLTPTHAASPVYRRYKHFD 271
Query: 292 WLYERLLVKFGSAIPIPSLPDKQVTGRFEEEFIKMRMERLQAWMTRMCRHPVISESEVFQ 351
WLY RLL KF + I +P LP+KQ TGRFEE+FI+ R RL WM M HPV+S+ E FQ
Sbjct: 272 WLYNRLLHKF-TVISVPHLPEKQATGRFEEDFIEKRKRRLILWMDHMTSHPVLSQYEGFQ 330
Query: 352 QFLNFRDEKEWKTGKRKAERDELAGVMIFSTMEPEAPDLDLVEIEQKCEAVGKFTKAMDD 411
FL+ D+K+WK GKR+AE+DE+ G T + DL ++E + + F+K MDD
Sbjct: 331 HFLSCLDDKQWKMGKRRAEKDEMVGASFLLTFQIPTEHQDLQDVEDRVDTFKAFSKKMDD 390
Query: 412 GVKELLTVGQEHWKRCTGPLPKEYQKIGKALQSLATVFSSSGYQGETDLNDAITEAGKTY 471
V +L TV E ++ G KE+QK+G A Q+++ F LN AI+ G+TY
Sbjct: 391 SVLQLSTVASELVRKHVGGFRKEFQKLGSAFQAISHSFQMDPPFCSEALNSAISHTGRTY 450
Query: 472 EEIASLVAEQPKKDLHFLMECNHEYKGFLGCFPDIIGTHKGAIEKVKESDKLVATSKITL 531
E I + AEQPK DL +++ Y+G L FPDII KGA KVKES ++ ++
Sbjct: 451 EAIGEMFAEQPKNDLFQMLDTLSLYQGLLSNFPDIIHLQKGAFAKVKESQRMSDEGRMVQ 510
Query: 532 QDKQNMVKRVSIMSYALQAEMNHFHSNRIYDYNSVIRLYLEQQVQFYETIAEKLRQALSR 591
+ + +R ++ +ALQAEMNHFH R D+ +++ YL QQ+ FY+ + ++L + L
Sbjct: 511 DEADGIRRRCRVVGFALQAEMNHFHQRRELDFKHMMQNYLRQQILFYQRVGQQLEKTLRM 570
Query: 592 F 592
+
Sbjct: 571 Y 571
>gi|224177511 sorting nexin 18 isoform c [Homo sapiens]
Length = 591
Score = 299 bits (765), Expect = 6e-81
Identities = 200/557 (35%), Positives = 273/557 (49%), Gaps = 61/557 (10%)
Query: 1 MATKARVMYDFAAE-PGNNELTVNEGEIITITNPDVGGGWLEGRNIKGERGLVPTDYVEI 59
MA +AR +YDF +E PG E+++ E E++++ + GWLEG N +G+RGL P YV++
Sbjct: 1 MALRARALYDFRSENPG--EISLREHEVLSLCSEQDIEGWLEGVNSRGDRGLFPASYVQV 58
Query: 60 LPSDGKDQFSCGNSVADQAFLDSLSASTAQASSSAASNNHQVGSGNDPWSAWSASKSGNW 119
+ + G A + + + + S P A+ A
Sbjct: 59 IRAPEPGPAGDGGPGAPARYANVPPGGFEPLPVAPPA------SFKPPPDAFQALLQPQ- 111
Query: 120 ESSEGWGAQPEGAGAQRNTNTPNNWDTAFGHPQAYQG---PATGDDDDWDEDWD------ 170
++ QP GAG P PQ G + G DDDWD++WD
Sbjct: 112 QAPPPSTFQPPGAGF------PYGGGALQPSPQQLYGGYQASQGSDDDWDDEWDDSSTVA 165
Query: 171 ---GPKSSSYFKD---SESADAGGA--------------QRGNS---------RASSSSM 201
G S + D S SA G A RG S SS+++
Sbjct: 166 DEPGALGSGAYPDLDGSSSAGVGAAGRYRLSTRSDLSLGSRGGSVPPQHHPSGPKSSATV 225
Query: 202 KIPLNKFPGFAKPGTEQYLL--AKQLAKPKEKIPIIVGDYGPMWVYPTSTFDCVVADPRK 259
LN+F F K G E ++L A K +K+ +++G YGP W F C + DP K
Sbjct: 226 SRNLNRFSTFVKSGGEAFVLGEASGFVKDGDKLCVVLGPYGPEWQENPYPFQCTIDDPTK 285
Query: 260 GSKMYGLKSYIEYQLTPTNTNRSVNHRYKHFDWLYERLLVKFGSAIPIPSLPDKQVTGRF 319
+K G+KSYI Y+L PT+T V+ RYKHFDWLY RL KF I +P LP+KQ TGRF
Sbjct: 286 QTKFKGMKSYISYKLVPTHTQVPVHRRYKHFDWLYARLAEKF-PVISVPHLPEKQATGRF 344
Query: 320 EEEFIKMRMERLQAWMTRMCRHPVISESEVFQQFL---NFRDEKEWKTGKRKAERDELAG 376
EE+FI R + L WM M HPV+++ +VFQ FL + DEK WK GKRKAE+DE+ G
Sbjct: 345 EEDFISKRRKGLIWWMNHMASHPVLAQCDVFQHFLTCPSSTDEKAWKQGKRKAEKDEMVG 404
Query: 377 VMIFSTME-PEAPDLDLVEIEQKCEAVGKFTKAMDDGVKELLTVGQEHWKRCTGPLPKEY 435
F T+ P A LDL E+E K + FTK MDD +L E ++ KEY
Sbjct: 405 ANFFLTLSTPPAAALDLQEVESKIDGFKCFTKKMDDSALQLNHTANEFARKQVTGFKKEY 464
Query: 436 QKIGKALQSLATVFSSSGYQGETDLNDAITEAGKTYEEIASLVAEQPKKDLHFLMECNHE 495
QK+G++ + L+ F LN AI G Y+ I L AEQP++DL +M+
Sbjct: 465 QKVGQSFRGLSQAFELDQQAFSVGLNQAIAFTGDAYDAIGELFAEQPRQDLDPVMDLLAL 524
Query: 496 YKGFLGCFPDIIGTHKG 512
Y+G L FPDII KG
Sbjct: 525 YQGHLANFPDIIHVQKG 541
>gi|157057543 sorting nexin 18 isoform b [Homo sapiens]
Length = 628
Score = 299 bits (765), Expect = 6e-81
Identities = 200/557 (35%), Positives = 273/557 (49%), Gaps = 61/557 (10%)
Query: 1 MATKARVMYDFAAE-PGNNELTVNEGEIITITNPDVGGGWLEGRNIKGERGLVPTDYVEI 59
MA +AR +YDF +E PG E+++ E E++++ + GWLEG N +G+RGL P YV++
Sbjct: 1 MALRARALYDFRSENPG--EISLREHEVLSLCSEQDIEGWLEGVNSRGDRGLFPASYVQV 58
Query: 60 LPSDGKDQFSCGNSVADQAFLDSLSASTAQASSSAASNNHQVGSGNDPWSAWSASKSGNW 119
+ + G A + + + + S P A+ A
Sbjct: 59 IRAPEPGPAGDGGPGAPARYANVPPGGFEPLPVAPPA------SFKPPPDAFQALLQPQ- 111
Query: 120 ESSEGWGAQPEGAGAQRNTNTPNNWDTAFGHPQAYQG---PATGDDDDWDEDWD------ 170
++ QP GAG P PQ G + G DDDWD++WD
Sbjct: 112 QAPPPSTFQPPGAGF------PYGGGALQPSPQQLYGGYQASQGSDDDWDDEWDDSSTVA 165
Query: 171 ---GPKSSSYFKD---SESADAGGA--------------QRGNS---------RASSSSM 201
G S + D S SA G A RG S SS+++
Sbjct: 166 DEPGALGSGAYPDLDGSSSAGVGAAGRYRLSTRSDLSLGSRGGSVPPQHHPSGPKSSATV 225
Query: 202 KIPLNKFPGFAKPGTEQYLL--AKQLAKPKEKIPIIVGDYGPMWVYPTSTFDCVVADPRK 259
LN+F F K G E ++L A K +K+ +++G YGP W F C + DP K
Sbjct: 226 SRNLNRFSTFVKSGGEAFVLGEASGFVKDGDKLCVVLGPYGPEWQENPYPFQCTIDDPTK 285
Query: 260 GSKMYGLKSYIEYQLTPTNTNRSVNHRYKHFDWLYERLLVKFGSAIPIPSLPDKQVTGRF 319
+K G+KSYI Y+L PT+T V+ RYKHFDWLY RL KF I +P LP+KQ TGRF
Sbjct: 286 QTKFKGMKSYISYKLVPTHTQVPVHRRYKHFDWLYARLAEKF-PVISVPHLPEKQATGRF 344
Query: 320 EEEFIKMRMERLQAWMTRMCRHPVISESEVFQQFL---NFRDEKEWKTGKRKAERDELAG 376
EE+FI R + L WM M HPV+++ +VFQ FL + DEK WK GKRKAE+DE+ G
Sbjct: 345 EEDFISKRRKGLIWWMNHMASHPVLAQCDVFQHFLTCPSSTDEKAWKQGKRKAEKDEMVG 404
Query: 377 VMIFSTME-PEAPDLDLVEIEQKCEAVGKFTKAMDDGVKELLTVGQEHWKRCTGPLPKEY 435
F T+ P A LDL E+E K + FTK MDD +L E ++ KEY
Sbjct: 405 ANFFLTLSTPPAAALDLQEVESKIDGFKCFTKKMDDSALQLNHTANEFARKQVTGFKKEY 464
Query: 436 QKIGKALQSLATVFSSSGYQGETDLNDAITEAGKTYEEIASLVAEQPKKDLHFLMECNHE 495
QK+G++ + L+ F LN AI G Y+ I L AEQP++DL +M+
Sbjct: 465 QKVGQSFRGLSQAFELDQQAFSVGLNQAIAFTGDAYDAIGELFAEQPRQDLDPVMDLLAL 524
Query: 496 YKGFLGCFPDIIGTHKG 512
Y+G L FPDII KG
Sbjct: 525 YQGHLANFPDIIHVQKG 541
>gi|153791707 sorting nexin family member 30 [Homo sapiens]
Length = 437
Score = 66.6 bits (161), Expect = 6e-11
Identities = 82/357 (22%), Positives = 141/357 (39%), Gaps = 63/357 (17%)
Query: 253 VVADPRKGSKMYGLKSYIEYQLTPTNTN-------RSVNHRYKHFDWLYERLLVKFGSAI 305
+V DP+K + +++YI Y++T +T SV RY+ FDWL +L + +
Sbjct: 94 IVDDPKK--HVCTMETYITYRITTKSTRVEFDLPEYSVRRRYQDFDWLRSKLEESQPTHL 151
Query: 306 PIPSLPDK----QVTGRFEEEFIKMRMERLQAWMTRMCRHPVISESEVFQQFLNFRDEKE 361
IP LP+K V RF EEF++ R + L ++ R+ HPV+S +E F FL +D
Sbjct: 152 -IPPLPEKFVVKGVVDRFSEEFVETRRKALDKFLKRITDHPVLSFNEHFNIFLTAKDLNA 210
Query: 362 WK-----------------TGKRKAERDELAGVMIFSTMEPEAPDLDLVEIEQKCEAVGK 404
+K TG K L I ++ A L ++ +
Sbjct: 211 YKKQGIALLTRMGESVKHVTGGYKLRTRPLEFAAIGDYLDTFALKLGTID-----RIAQR 265
Query: 405 FTKAMDDGVKELLTVGQEH--WKRCTGPLPKEYQKIGKALQSLATVFSSSGYQGETDLND 462
K + + EL G + W G L + + + + + +T +L D
Sbjct: 266 IIKEEIEYLVELREYGPVYSTWSALEGELAEPLEGVSACIGNCSTALE--------ELTD 317
Query: 463 AITEAGKTYEEIASLVAEQPKKDLHFLMECNHEYKGFLGCFPDIIGTHKGAIEKVKESDK 522
+TE L ++ K L + EY+ L A+ KE
Sbjct: 318 DMTEDFLPVLREYILYSDSMKSVLKKRDQVQAEYEAKL-----------EAVALRKEDRP 366
Query: 523 LVATSKITLQDKQNMVKRVSIMSYALQAEMNHFHSNRIYDYNSVIRLYLEQQVQFYE 579
V QD R+ + L+A+M + +N+ D+ ++ ++ +Q+YE
Sbjct: 367 KVPADVEKCQD------RMECFNADLKADMERWQNNKRQDFRQLLMGMADKNIQYYE 417
>gi|23111038 sorting nexin 2 [Homo sapiens]
Length = 519
Score = 58.5 bits (140), Expect = 2e-08
Identities = 99/497 (19%), Positives = 183/497 (36%), Gaps = 84/497 (16%)
Query: 138 TNTPNNWDTAFGHPQAYQGPATGDDDDWDEDWDGPKSSSYFKDSESADAGGAQRGNSRAS 197
T+T + +++ P+ PA+ +D + +GPK + D + D
Sbjct: 29 TSTVSTLESSPSSPE----PASLPAEDISANSNGPKPTEVVLDDDREDLFAEATEEVSLD 84
Query: 198 SSSMKIPLNKFPGFA-KPGTEQYLLAKQLAKPKEKIPIIVGDYGPMWVYPTSTFDCV--- 253
S + L+ P A P T L+A ++ P+I D + + D
Sbjct: 85 SPEREPILSSEPSPAVTPVTPTTLIAPRIESKSMSAPVIF-DRSREEIEEEANGDIFDIE 143
Query: 254 --VADPRKGSKMYGLKSYIEYQLTP-------TNTNRSVNHRYKHFDWLYERLLVKF-GS 303
V+DP K G+ +Y+ Y++T + + SV R+ F L+ +L K+
Sbjct: 144 IGVSDPEKVGD--GMNAYMAYRVTTKTSLSMFSKSEFSVKRRFSDFLGLHSKLASKYLHV 201
Query: 304 AIPIPSLPDKQVTGRFE----------EEFIKMRMERLQAWMTRMCRHPVISESEVFQQF 353
+P P+K + G + EF++ R L+ ++ R +HP + + +QF
Sbjct: 202 GYIVPPAPEKSIVGMTKVKVGKEDSSSTEFVEKRRAALERYLQRTVKHPTLLQDPDLRQF 261
Query: 354 LNFRDEKEWKTGKRKAERDELAGVMIFSTMEPEAPDLDLVEIEQKCEAVGKFTKAMDDGV 413
L E R L+G I L + + +AV K T M++
Sbjct: 262 L------ESSELPRAVNTQALSGAGI------------LRMVNKAADAVNKMTIKMNES- 302
Query: 414 KELLTVGQEHWKRCTGPLPKEYQKI------GKALQSLATVFSSS-----GYQGETDLND 462
Q+ ++ L K + + K L + F+ S + T L+
Sbjct: 303 DAWFEEKQQQFENLDQQLRKLHVSVEALVCHRKELSANTAAFAKSAAMLGNSEDHTALSR 362
Query: 463 AITEAGKTYEEIASLVAEQPKKDLHFLMECNHEYKGFLGCFPDIIGTHKGAIEKVK---- 518
A+++ + E+I L EQ D + E +Y + + +K +
Sbjct: 363 ALSQLAEVEEKIDQLHQEQAFADFYMFSELLSDYIRLIAAVKGVFDHRMKCWQKWEDAQI 422
Query: 519 --------ESDKLVATSKITLQDKQNMVKR-----------VSIMSYALQAEMNHFHSNR 559
E+ +VA +Q +N ++ +S ++ E+ F R
Sbjct: 423 TLLKKREAEAKMMVANKPDKIQQAKNEIREWEAKVQQGERDFEQISKTIRKEVGRFEKER 482
Query: 560 IYDYNSVIRLYLEQQVQ 576
+ D+ +VI YLE VQ
Sbjct: 483 VKDFKTVIIKYLESLVQ 499
>gi|23943858 sorting nexin 8 [Homo sapiens]
Length = 465
Score = 55.1 bits (131), Expect = 2e-07
Identities = 63/267 (23%), Positives = 112/267 (41%), Gaps = 48/267 (17%)
Query: 269 YIEYQLTPTNTNRSVNHRYKHFDWLYERLLVKFGSAIPIPSLPDKQVTGRFEEEFIKMRM 328
++EY+++ SV RY F E LL KF + +P+LP K++ G + EFI+ R
Sbjct: 92 HVEYEVSSQRFKSSVYRRYNDFVVFQEMLLHKFPYRM-VPALPPKRMLGA-DREFIEARR 149
Query: 329 ERLQAWMTRMCRHPVISESEVFQQFLNFRDEKEWKTGKRKAE--RDELAGVMIFSTMEPE 386
L+ ++ + RHP+ SE V + FL+F K A+ DE + + +
Sbjct: 150 RALKRFVNLVARHPLFSEDVVLKLFLSFSGSDVQNKLKESAQCVGDEFLNCKLATRAKDF 209
Query: 387 AP---------DLDLV--------EIEQKCEAVGKFTKAMDDGV------KELLTVGQEH 423
P +L+ ++ + E + ++A+D+ KEL +G +
Sbjct: 210 LPADIQAQFAISRELIRNIYNSFHKLRDRAERIA--SRAIDNAADLLIFGKELSAIGSD- 266
Query: 424 WKRCTGPLP-------KEYQKIGKALQSLATVFS----SSGYQGETDLNDAITEAGKTYE 472
T PLP + + +AL+ L+ F+ + QG+ + ND + + +
Sbjct: 267 ----TTPLPSWAALNSSTWGSLKQALKGLSVEFALLADKAAQQGKQEENDVVEKLNLFLD 322
Query: 473 EIAS---LVAEQPKKDLHFLMECNHEY 496
+ S L K LH H+Y
Sbjct: 323 LLQSYKDLCERHEKGVLHKHQRALHKY 349
>gi|24797143 sorting nexin 14 isoform b [Homo sapiens]
Length = 893
Score = 50.4 bits (119), Expect = 4e-06
Identities = 25/86 (29%), Positives = 44/86 (51%), Gaps = 8/86 (9%)
Query: 278 NTNRSVNHRYKHFD--------WLYERLLVKFGSAIPIPSLPDKQVTGRFEEEFIKMRME 329
N R+V H +H+ ++ E L +F A P LP K++ G EF+K + E
Sbjct: 546 NDRRAVGHEPEHWSVYRRYLEFYVLESKLTEFHGAFPDAQLPSKRIIGPKNYEFLKSKRE 605
Query: 330 RLQAWMTRMCRHPVISESEVFQQFLN 355
Q ++ ++ +HP +S S++ FL+
Sbjct: 606 EFQEYLQKLLQHPELSNSQLLADFLS 631
>gi|24797145 sorting nexin 14 isoform a [Homo sapiens]
Length = 946
Score = 50.4 bits (119), Expect = 4e-06
Identities = 25/86 (29%), Positives = 44/86 (51%), Gaps = 8/86 (9%)
Query: 278 NTNRSVNHRYKHFD--------WLYERLLVKFGSAIPIPSLPDKQVTGRFEEEFIKMRME 329
N R+V H +H+ ++ E L +F A P LP K++ G EF+K + E
Sbjct: 599 NDRRAVGHEPEHWSVYRRYLEFYVLESKLTEFHGAFPDAQLPSKRIIGPKNYEFLKSKRE 658
Query: 330 RLQAWMTRMCRHPVISESEVFQQFLN 355
Q ++ ++ +HP +S S++ FL+
Sbjct: 659 EFQEYLQKLLQHPELSNSQLLADFLS 684
>gi|194294540 sorting nexin 7 isoform a [Homo sapiens]
Length = 451
Score = 48.9 bits (115), Expect = 1e-05
Identities = 66/333 (19%), Positives = 131/333 (39%), Gaps = 36/333 (10%)
Query: 266 LKSYIEYQLTPTNTNRS--------VNHRYKHFDWLYERLLVKFGSAIPIPSLPDKQVTG 317
++++I Y++ T T+R V RY+ F WL +L + I IP LP+K +
Sbjct: 110 IETFITYRII-TKTSRGEFDSSEFEVRRRYQDFLWLKGKLEEAHPTLI-IPPLPEKFIVK 167
Query: 318 ----RFEEEFIKMRMERLQAWMTRMCRHPVISESEVFQQFLNFRDEKEWKTGKRKAERDE 373
RF ++FI+ R + L ++ R+ HP ++ +E F+ FL + W+ K +
Sbjct: 168 GMVERFNDDFIETRRKALHKFLNRIADHPTLTFNEDFKIFLT---AQAWELSSHKKQGPG 224
Query: 374 LAGVMIFSTMEPEAPDLDLVEIEQKCEAVGKFTKAMDDGVKELLTVGQEHWKRCTGPLPK 433
L M + + + ++ + F + + + + Q +K +
Sbjct: 225 LLSRMGQTVRAVASSMRGVKNRPEEFMEMNNFIELFSQKINLIDKISQRIYKE-----ER 279
Query: 434 EYQKIGKALQSLATVFSSSGYQGETDLNDAITEAGKTYEEIASLVAEQPKKDLHFLMECN 493
EY K + ++S+S E DL D + + + ++ L+
Sbjct: 280 EYFDEMKEYGPIHILWSAS----EEDLVDTLKDVASCIDRCCKATEKRMSGLSEALLPVV 335
Query: 494 HEYKGFLGCFPDIIGTHKGAIEKVKESDKLV-------ATSKITLQDKQNMVKRVSIMSY 546
HEY + ++G K + E D V A + + ++ + +V +
Sbjct: 336 HEYVLYSEM---LMGVMKRRDQIQAELDSKVEVLTYKKADTDLLPEEIGKLEDKVECANN 392
Query: 547 ALQAEMNHFHSNRIYDYNSVIRLYLEQQVQFYE 579
AL+A+ + N D E+ + +YE
Sbjct: 393 ALKADWERWKQNMQNDIKLAFTDMAEENIHYYE 425
>gi|67514036 SH3-domain kinase binding protein 1 isoform b [Homo
sapiens]
Length = 628
Score = 48.5 bits (114), Expect = 2e-05
Identities = 23/59 (38%), Positives = 41/59 (69%), Gaps = 3/59 (5%)
Query: 6 RVMYDFAAEPGNNELTVNEGEIITITNPD-VGGGWLEGRNIKGERGLVPTDYVEILPSD 63
+V++ + A+ ++ELT+ EG+I+T+ N D + GW EG + G RG+ P ++V++LP D
Sbjct: 236 KVIFPYEAQ-NDDELTIKEGDIVTLINKDCIDVGWWEG-ELNGRRGVFPDNFVKLLPPD 292
>gi|13994242 SH3-domain kinase binding protein 1 isoform a [Homo
sapiens]
Length = 665
Score = 48.5 bits (114), Expect = 2e-05
Identities = 23/59 (38%), Positives = 41/59 (69%), Gaps = 3/59 (5%)
Query: 6 RVMYDFAAEPGNNELTVNEGEIITITNPD-VGGGWLEGRNIKGERGLVPTDYVEILPSD 63
+V++ + A+ ++ELT+ EG+I+T+ N D + GW EG + G RG+ P ++V++LP D
Sbjct: 273 KVIFPYEAQ-NDDELTIKEGDIVTLINKDCIDVGWWEG-ELNGRRGVFPDNFVKLLPPD 329
Score = 40.8 bits (94), Expect = 0.004
Identities = 25/62 (40%), Positives = 39/62 (62%), Gaps = 3/62 (4%)
Query: 4 KARVMYDFAAEPGNNELTVNEGEIITITNPDVGGGWLEGRNIKGERGLVPTDYVEILPSD 63
+A V +D+ A+ ++ELT++ GEIIT + GGW EG+ I G RGL P ++V + +
Sbjct: 3 EAIVEFDYQAQH-DDELTISVGEIITNIRKE-DGGWWEGQ-INGRRGLFPDNFVREIKKE 59
Query: 64 GK 65
K
Sbjct: 60 MK 61
>gi|155030230 sorbin and SH3 domain containing 3 isoform 1 [Homo
sapiens]
Length = 671
Score = 46.6 bits (109), Expect = 6e-05
Identities = 25/59 (42%), Positives = 39/59 (66%), Gaps = 3/59 (5%)
Query: 5 ARVMYDFAAEPGNNELTVNEGEIITITNPDVGGGWLEGRNIKGERGLVPTDYVEILPSD 63
AR+ +DF A+ ELT+ +G+I+ I + +V WLEG + G G+ P +YVE+LP+D
Sbjct: 385 ARLKFDFQAQ-SPKELTLQKGDIVYI-HKEVDKNWLEGEH-HGRLGIFPANYVEVLPAD 440
>gi|65301112 sorbin and SH3 domain containing 3 isoform 2 [Homo
sapiens]
Length = 329
Score = 46.6 bits (109), Expect = 6e-05
Identities = 25/59 (42%), Positives = 39/59 (66%), Gaps = 3/59 (5%)
Query: 5 ARVMYDFAAEPGNNELTVNEGEIITITNPDVGGGWLEGRNIKGERGLVPTDYVEILPSD 63
AR+ +DF A+ ELT+ +G+I+ I + +V WLEG + G G+ P +YVE+LP+D
Sbjct: 43 ARLKFDFQAQ-SPKELTLQKGDIVYI-HKEVDKNWLEGEH-HGRLGIFPANYVEVLPAD 98
>gi|23111055 sorting nexin 7 isoform b [Homo sapiens]
Length = 336
Score = 45.4 bits (106), Expect = 1e-04
Identities = 33/117 (28%), Positives = 59/117 (50%), Gaps = 17/117 (14%)
Query: 266 LKSYIEYQLTPTNTNRS--------VNHRYKHFDWLYERLLVKFGSAIPIPSLPDKQVTG 317
++++I Y++ T T+R V RY+ F WL +L + I IP LP+K +
Sbjct: 46 IETFITYRII-TKTSRGEFDSSEFEVRRRYQDFLWLKGKLEEAHPTLI-IPPLPEKFIVK 103
Query: 318 ----RFEEEFIKMRMERLQAWMTRMCRHPVISESEVFQQFLNFRDEKEWKTGKRKAE 370
RF ++FI+ R + L ++ R+ HP ++ +E F+ FL + W+ K +
Sbjct: 104 GMVERFNDDFIETRRKALHKFLNRIADHPTLTFNEDFKIFLT---AQAWELSSHKKQ 157
>gi|68348709 formin binding protein 1-like isoform 1 [Homo sapiens]
Length = 551
Score = 45.1 bits (105), Expect = 2e-04
Identities = 20/46 (43%), Positives = 27/46 (58%), Gaps = 2/46 (4%)
Query: 16 GNNE--LTVNEGEIITITNPDVGGGWLEGRNIKGERGLVPTDYVEI 59
G+NE L + EGE++ I D G GW R GE G VPT Y+++
Sbjct: 493 GHNEGTLAMKEGEVLYIIEEDKGDGWTRARRQNGEEGYVPTSYIDV 538
>gi|41581463 formin binding protein 1-like isoform 2 [Homo sapiens]
Length = 547
Score = 45.1 bits (105), Expect = 2e-04
Identities = 20/46 (43%), Positives = 27/46 (58%), Gaps = 2/46 (4%)
Query: 16 GNNE--LTVNEGEIITITNPDVGGGWLEGRNIKGERGLVPTDYVEI 59
G+NE L + EGE++ I D G GW R GE G VPT Y+++
Sbjct: 493 GHNEGTLAMKEGEVLYIIEEDKGDGWTRARRQNGEEGYVPTSYIDV 538
>gi|223468657 SH3-domain GRB2-like 3 [Homo sapiens]
Length = 347
Score = 43.5 bits (101), Expect = 5e-04
Identities = 25/55 (45%), Positives = 32/55 (58%), Gaps = 3/55 (5%)
Query: 6 RVMYDFAAEPGNNELTVNEGEIITITNPDVGGGWLEGRNIKGERGLVPTDYVEIL 60
R +YDF E EL EG+IIT+TN + W EG I GE G P +YVE++
Sbjct: 291 RGLYDFEPE-NQGELGFKEGDIITLTN-QIDENWYEGM-IHGESGFFPINYVEVI 342
>gi|41406080 growth arrest-specific 7 isoform c [Homo sapiens]
Length = 476
Score = 43.1 bits (100), Expect = 7e-04
Identities = 24/62 (38%), Positives = 31/62 (50%), Gaps = 3/62 (4%)
Query: 4 KARVMYDFAAEPGNNELTVNEGEIITITN-PDVGGGWLEGRNIKGERGLVPTDYVEILPS 62
+ R +Y F+ E L GE+IT+ PD GGW EG G RG P YV++L
Sbjct: 5 RCRTLYPFSGERHGQGLRFAAGELITLLQVPD--GGWWEGEKEDGLRGWFPASYVQLLEK 62
Query: 63 DG 64
G
Sbjct: 63 PG 64
>gi|4506931 SH3-domain GRB2-like 2 [Homo sapiens]
Length = 352
Score = 43.1 bits (100), Expect = 7e-04
Identities = 25/55 (45%), Positives = 31/55 (56%), Gaps = 3/55 (5%)
Query: 6 RVMYDFAAEPGNNELTVNEGEIITITNPDVGGGWLEGRNIKGERGLVPTDYVEIL 60
R +YDF E EL EG+IIT+TN + W EG + G G P +YVEIL
Sbjct: 296 RALYDFEPE-NEGELGFKEGDIITLTN-QIDENWYEGM-LHGHSGFFPINYVEIL 347
>gi|222080100 BAI1-associated protein 2 isoform 4 [Homo sapiens]
Length = 534
Score = 42.7 bits (99), Expect = 0.001
Identities = 21/65 (32%), Positives = 35/65 (53%), Gaps = 1/65 (1%)
Query: 4 KARVMYDFAAEPGNNELTVNEGEIITITNPDVGGGWLEGRNIKGE-RGLVPTDYVEILPS 62
+ + ++ AA + L+ EG++IT+ P+ GW G + K + RG P Y +L S
Sbjct: 378 RVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEKTKMRGWFPFSYTRVLDS 437
Query: 63 DGKDQ 67
DG D+
Sbjct: 438 DGSDR 442
>gi|5453565 BAI1-associated protein 2 isoform 3 [Homo sapiens]
Length = 520
Score = 42.7 bits (99), Expect = 0.001
Identities = 21/65 (32%), Positives = 35/65 (53%), Gaps = 1/65 (1%)
Query: 4 KARVMYDFAAEPGNNELTVNEGEIITITNPDVGGGWLEGRNIKGE-RGLVPTDYVEILPS 62
+ + ++ AA + L+ EG++IT+ P+ GW G + K + RG P Y +L S
Sbjct: 378 RVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEKTKMRGWFPFSYTRVLDS 437
Query: 63 DGKDQ 67
DG D+
Sbjct: 438 DGSDR 442
>gi|9257197 BAI1-associated protein 2 isoform 1 [Homo sapiens]
Length = 521
Score = 42.7 bits (99), Expect = 0.001
Identities = 21/65 (32%), Positives = 35/65 (53%), Gaps = 1/65 (1%)
Query: 4 KARVMYDFAAEPGNNELTVNEGEIITITNPDVGGGWLEGRNIKGE-RGLVPTDYVEILPS 62
+ + ++ AA + L+ EG++IT+ P+ GW G + K + RG P Y +L S
Sbjct: 378 RVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEKTKMRGWFPFSYTRVLDS 437
Query: 63 DGKDQ 67
DG D+
Sbjct: 438 DGSDR 442
>gi|9257199 BAI1-associated protein 2 isoform 2 [Homo sapiens]
Length = 552
Score = 42.7 bits (99), Expect = 0.001
Identities = 21/65 (32%), Positives = 35/65 (53%), Gaps = 1/65 (1%)
Query: 4 KARVMYDFAAEPGNNELTVNEGEIITITNPDVGGGWLEGRNIKGE-RGLVPTDYVEILPS 62
+ + ++ AA + L+ EG++IT+ P+ GW G + K + RG P Y +L S
Sbjct: 378 RVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEKTKMRGWFPFSYTRVLDS 437
Query: 63 DGKDQ 67
DG D+
Sbjct: 438 DGSDR 442
>gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]
Length = 1220
Score = 42.7 bits (99), Expect = 0.001
Identities = 43/155 (27%), Positives = 65/155 (41%), Gaps = 24/155 (15%)
Query: 6 RVMYDFAAEPGNNELTVNEGEIITITNPDVGG------GWLEGRNIKGERGLVPTDYVEI 59
R +Y F + ++E+T+ G+I+ + V GWL G +KG+ G P +Y E
Sbjct: 746 RALYPFESR-SHDEITIQPGDIVMVKGEWVDESQTGEPGWLGGE-LKGKTGWFPANYAEK 803
Query: 60 LPSDG-----KDQFSCGNSVADQAFLDSLSASTAQASS--SAASNNHQVGSGNDPWSAWS 112
+P + K ++ A + L A A SS S NN S P S
Sbjct: 804 IPENEVPAPVKPVTDSTSAPAPKLALRETPAPLAVTSSEPSTTPNNWADFSSTWPTSTNE 863
Query: 113 ASKSGNWESSEGWGAQPE------GAGAQRNTNTP 141
++ NW++ W AQP G QR+ TP
Sbjct: 864 KPETDNWDA---WAAQPSLTVPSAGQLRQRSAFTP 895
Score = 33.5 bits (75), Expect = 0.57
Identities = 20/59 (33%), Positives = 33/59 (55%), Gaps = 4/59 (6%)
Query: 5 ARVMYDFAAEPGNNELTVNEGEIITITNPDVGGGW---LEGRNIKGERGLVPTDYVEIL 60
A+V+ + A G +LT+ G++I I + GG W L+ R K + G P +YV++L
Sbjct: 1079 AQVIASYTAT-GPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYVKLL 1136
>gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]
Length = 1721
Score = 42.7 bits (99), Expect = 0.001
Identities = 43/155 (27%), Positives = 65/155 (41%), Gaps = 24/155 (15%)
Query: 6 RVMYDFAAEPGNNELTVNEGEIITITNPDVGG------GWLEGRNIKGERGLVPTDYVEI 59
R +Y F + ++E+T+ G+I+ + V GWL G +KG+ G P +Y E
Sbjct: 746 RALYPFESR-SHDEITIQPGDIVMVKGEWVDESQTGEPGWLGGE-LKGKTGWFPANYAEK 803
Query: 60 LPSDG-----KDQFSCGNSVADQAFLDSLSASTAQASS--SAASNNHQVGSGNDPWSAWS 112
+P + K ++ A + L A A SS S NN S P S
Sbjct: 804 IPENEVPAPVKPVTDSTSAPAPKLALRETPAPLAVTSSEPSTTPNNWADFSSTWPTSTNE 863
Query: 113 ASKSGNWESSEGWGAQPE------GAGAQRNTNTP 141
++ NW++ W AQP G QR+ TP
Sbjct: 864 KPETDNWDA---WAAQPSLTVPSAGQLRQRSAFTP 895
Score = 33.5 bits (75), Expect = 0.57
Identities = 20/59 (33%), Positives = 33/59 (55%), Gaps = 4/59 (6%)
Query: 5 ARVMYDFAAEPGNNELTVNEGEIITITNPDVGGGW---LEGRNIKGERGLVPTDYVEIL 60
A+V+ + A G +LT+ G++I I + GG W L+ R K + G P +YV++L
Sbjct: 1079 AQVIASYTAT-GPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYVKLL 1136
>gi|23111026 sorting nexin 11 [Homo sapiens]
Length = 270
Score = 42.7 bits (99), Expect = 0.001
Identities = 29/108 (26%), Positives = 52/108 (48%), Gaps = 9/108 (8%)
Query: 254 VADPRKGSKMYGLKSYIEYQLTPTNTNRS-------VNHRYKHFDWLYERLLVKFGSAIP 306
V DPR ++ SY++Y++ +++ V RY+ F WL ++L G +P
Sbjct: 21 VQDPRVQNEG-SWNSYVDYKIFLHTNSKAFTAKTSCVRRRYREFVWLRKQLQRNAG-LVP 78
Query: 307 IPSLPDKQVTGRFEEEFIKMRMERLQAWMTRMCRHPVISESEVFQQFL 354
+P LP K +EFI+ R + LQ ++ ++ + V+ FL
Sbjct: 79 VPELPGKSTFFGTSDEFIEKRRQGLQHFLEKVLQSVVLLSDSQLHLFL 126
>gi|23111028 sorting nexin 11 [Homo sapiens]
Length = 270
Score = 42.7 bits (99), Expect = 0.001
Identities = 29/108 (26%), Positives = 52/108 (48%), Gaps = 9/108 (8%)
Query: 254 VADPRKGSKMYGLKSYIEYQLTPTNTNRS-------VNHRYKHFDWLYERLLVKFGSAIP 306
V DPR ++ SY++Y++ +++ V RY+ F WL ++L G +P
Sbjct: 21 VQDPRVQNEG-SWNSYVDYKIFLHTNSKAFTAKTSCVRRRYREFVWLRKQLQRNAG-LVP 78
Query: 307 IPSLPDKQVTGRFEEEFIKMRMERLQAWMTRMCRHPVISESEVFQQFL 354
+P LP K +EFI+ R + LQ ++ ++ + V+ FL
Sbjct: 79 VPELPGKSTFFGTSDEFIEKRRQGLQHFLEKVLQSVVLLSDSQLHLFL 126
>gi|4506929 SH3-domain GRB2-like 1 [Homo sapiens]
Length = 368
Score = 42.4 bits (98), Expect = 0.001
Identities = 22/55 (40%), Positives = 33/55 (60%), Gaps = 3/55 (5%)
Query: 6 RVMYDFAAEPGNNELTVNEGEIITITNPDVGGGWLEGRNIKGERGLVPTDYVEIL 60
+ +YDF E + EL +EG++IT+TN + W EG + G+ G P YVE+L
Sbjct: 312 KALYDFEPE-NDGELGFHEGDVITLTN-QIDENWYEGM-LDGQSGFFPLSYVEVL 363
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.131 0.393
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,487,402
Number of Sequences: 37866
Number of extensions: 1108358
Number of successful extensions: 3040
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 44
Number of HSP's successfully gapped in prelim test: 162
Number of HSP's that attempted gapping in prelim test: 2830
Number of HSP's gapped (non-prelim): 317
length of query: 595
length of database: 18,247,518
effective HSP length: 108
effective length of query: 487
effective length of database: 14,157,990
effective search space: 6894941130
effective search space used: 6894941130
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.