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Search of human proteins with 7706629
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7706629 purinergic receptor P2X2 isoform C [Homo sapiens]
(447 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7706629 purinergic receptor P2X2 isoform C [Homo sapiens] 933 0.0
gi|25092719 purinergic receptor P2X2 isoform A [Homo sapiens] 920 0.0
gi|25092733 purinergic receptor P2X2 isoform D [Homo sapiens] 905 0.0
gi|28416923 purinergic receptor P2X2 isoform B [Homo sapiens] 727 0.0
gi|28416921 purinergic receptor P2X2 isoform H [Homo sapiens] 727 0.0
gi|27881423 purinergic receptor P2X2 isoform I [Homo sapiens] 726 0.0
gi|28416927 purinergic receptor P2X4 [Homo sapiens] 319 4e-87
gi|28416925 purinergic receptor P2X3 [Homo sapiens] 301 1e-81
gi|28416935 purinergic receptor P2X5 isoform B [Homo sapiens] 280 2e-75
gi|28416933 purinergic receptor P2X5 isoform A [Homo sapiens] 274 1e-73
gi|4505545 purinergic receptor P2X1 [Homo sapiens] 272 5e-73
gi|157419148 purinergic receptor P2X6 isoform 1 [Homo sapiens] 261 7e-70
gi|227116341 purinergic receptor P2X6 isoform 2 [Homo sapiens] 234 2e-61
gi|29294631 purinergic receptor P2X7 [Homo sapiens] 218 7e-57
gi|28416937 purinergic receptor P2X5 isoform C [Homo sapiens] 117 2e-26
gi|150170670 piccolo isoform 2 [Homo sapiens] 38 0.016
gi|150378539 piccolo isoform 1 [Homo sapiens] 38 0.016
gi|54860079 nadrin isoform 1 [Homo sapiens] 37 0.036
gi|54860105 nadrin isoform 2 [Homo sapiens] 37 0.036
gi|23397666 transcriptional co-repressor Sin3A [Homo sapiens] 37 0.048
gi|223941785 transcriptional co-repressor Sin3A [Homo sapiens] 37 0.048
gi|223941782 transcriptional co-repressor Sin3A [Homo sapiens] 37 0.048
gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 36 0.062
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 36 0.081
gi|155030236 ribonuclease III, nuclear isoform 2 [Homo sapiens] 36 0.081
gi|155030234 ribonuclease III, nuclear isoform 1 [Homo sapiens] 36 0.081
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 35 0.11
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 35 0.11
gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 35 0.11
gi|39812378 RAN binding protein 9 [Homo sapiens] 35 0.18
>gi|7706629 purinergic receptor P2X2 isoform C [Homo sapiens]
Length = 447
Score = 933 bits (2412), Expect = 0.0
Identities = 447/447 (100%), Positives = 447/447 (100%)
Query: 1 MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYV 60
MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYV
Sbjct: 1 MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYV 60
Query: 61 FIVQKSYQESETGPESSIITKVKGITTSEHKVWDVEEYVKPPESIRVHNATCLSDADCVA 120
FIVQKSYQESETGPESSIITKVKGITTSEHKVWDVEEYVKPPESIRVHNATCLSDADCVA
Sbjct: 61 FIVQKSYQESETGPESSIITKVKGITTSEHKVWDVEEYVKPPESIRVHNATCLSDADCVA 120
Query: 121 GELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQFLGTMAPNFTILIKNSIH 180
GELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQFLGTMAPNFTILIKNSIH
Sbjct: 121 GELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQFLGTMAPNFTILIKNSIH 180
Query: 181 YPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFKLGFIVEKAGESFTELAHKGGVIGV 240
YPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFKLGFIVEKAGESFTELAHKGGVIGV
Sbjct: 181 YPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFKLGFIVEKAGESFTELAHKGGVIGV 240
Query: 241 IINWDCDLDLPASECNPKYSFRRLDPKHVPASSGYNFRFAKYYKINGTTTRTLIKAYGIR 300
IINWDCDLDLPASECNPKYSFRRLDPKHVPASSGYNFRFAKYYKINGTTTRTLIKAYGIR
Sbjct: 241 IINWDCDLDLPASECNPKYSFRRLDPKHVPASSGYNFRFAKYYKINGTTTRTLIKAYGIR 300
Query: 301 IDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCDWILLTFMNKNKVYSHKKFDKVCTP 360
IDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCDWILLTFMNKNKVYSHKKFDKVCTP
Sbjct: 301 IDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCDWILLTFMNKNKVYSHKKFDKVCTP 360
Query: 361 SHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISAP 420
SHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISAP
Sbjct: 361 SHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISAP 420
Query: 421 SEQMVDTPASEPAQASTPTDPKGLAQL 447
SEQMVDTPASEPAQASTPTDPKGLAQL
Sbjct: 421 SEQMVDTPASEPAQASTPTDPKGLAQL 447
>gi|25092719 purinergic receptor P2X2 isoform A [Homo sapiens]
Length = 471
Score = 920 bits (2377), Expect = 0.0
Identities = 447/471 (94%), Positives = 447/471 (94%), Gaps = 24/471 (5%)
Query: 1 MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYV 60
MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYV
Sbjct: 1 MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYV 60
Query: 61 FIVQKSYQESETGPESSIITKVKGITTSEHKVWDVEEYVKPPE----------------- 103
FIVQKSYQESETGPESSIITKVKGITTSEHKVWDVEEYVKPPE
Sbjct: 61 FIVQKSYQESETGPESSIITKVKGITTSEHKVWDVEEYVKPPEGGSVFSIITRVEATHSQ 120
Query: 104 -------SIRVHNATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVED 156
SIRVHNATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVED
Sbjct: 121 TQGTCPESIRVHNATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVED 180
Query: 157 GASVSQFLGTMAPNFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFK 216
GASVSQFLGTMAPNFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFK
Sbjct: 181 GASVSQFLGTMAPNFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFK 240
Query: 217 LGFIVEKAGESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPKHVPASSGYN 276
LGFIVEKAGESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPKHVPASSGYN
Sbjct: 241 LGFIVEKAGESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPKHVPASSGYN 300
Query: 277 FRFAKYYKINGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCD 336
FRFAKYYKINGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCD
Sbjct: 301 FRFAKYYKINGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCD 360
Query: 337 WILLTFMNKNKVYSHKKFDKVCTPSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSG 396
WILLTFMNKNKVYSHKKFDKVCTPSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSG
Sbjct: 361 WILLTFMNKNKVYSHKKFDKVCTPSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSG 420
Query: 397 QEGQQGAECGPAFPPLRPCPISAPSEQMVDTPASEPAQASTPTDPKGLAQL 447
QEGQQGAECGPAFPPLRPCPISAPSEQMVDTPASEPAQASTPTDPKGLAQL
Sbjct: 421 QEGQQGAECGPAFPPLRPCPISAPSEQMVDTPASEPAQASTPTDPKGLAQL 471
>gi|25092733 purinergic receptor P2X2 isoform D [Homo sapiens]
Length = 497
Score = 905 bits (2340), Expect = 0.0
Identities = 447/497 (89%), Positives = 447/497 (89%), Gaps = 50/497 (10%)
Query: 1 MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYV 60
MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYV
Sbjct: 1 MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYV 60
Query: 61 FIVQKSYQESETGPESSIITKVKGITTSEHKVWDVEEYVKPPE----------------- 103
FIVQKSYQESETGPESSIITKVKGITTSEHKVWDVEEYVKPPE
Sbjct: 61 FIVQKSYQESETGPESSIITKVKGITTSEHKVWDVEEYVKPPEGGSVFSIITRVEATHSQ 120
Query: 104 -------SIRVHNATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVED 156
SIRVHNATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVED
Sbjct: 121 TQGTCPESIRVHNATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVED 180
Query: 157 GASVSQFLGTMAPNFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFK 216
GASVSQFLGTMAPNFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFK
Sbjct: 181 GASVSQFLGTMAPNFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFK 240
Query: 217 LGFIVEKAGESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPKHVPASSGYN 276
LGFIVEKAGESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPKHVPASSGYN
Sbjct: 241 LGFIVEKAGESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPKHVPASSGYN 300
Query: 277 FRFAKYYKINGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGV------ 330
FRFAKYYKINGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGV
Sbjct: 301 FRFAKYYKINGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVVRNPLW 360
Query: 331 --------------------GSFLCDWILLTFMNKNKVYSHKKFDKVCTPSHPSGSWPVT 370
GSFLCDWILLTFMNKNKVYSHKKFDKVCTPSHPSGSWPVT
Sbjct: 361 GPSGCGGSTRPLHTGLCWPQGSFLCDWILLTFMNKNKVYSHKKFDKVCTPSHPSGSWPVT 420
Query: 371 LARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISAPSEQMVDTPAS 430
LARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISAPSEQMVDTPAS
Sbjct: 421 LARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISAPSEQMVDTPAS 480
Query: 431 EPAQASTPTDPKGLAQL 447
EPAQASTPTDPKGLAQL
Sbjct: 481 EPAQASTPTDPKGLAQL 497
>gi|28416923 purinergic receptor P2X2 isoform B [Homo sapiens]
Length = 404
Score = 727 bits (1877), Expect = 0.0
Identities = 360/400 (90%), Positives = 362/400 (90%), Gaps = 35/400 (8%)
Query: 1 MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYV 60
MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYV
Sbjct: 1 MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYV 60
Query: 61 FIVQKSYQESETGPESSIITKVKGITTSEHKVWDVEEYVKPPE----------------- 103
FIVQKSYQESETGPESSIITKVKGITTSEHKVWDVEEYVKPPE
Sbjct: 61 FIVQKSYQESETGPESSIITKVKGITTSEHKVWDVEEYVKPPEGGSVFSIITRVEATHSQ 120
Query: 104 -------SIRVHNATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVED 156
SIRVHNATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVED
Sbjct: 121 TQGTCPESIRVHNATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVED 180
Query: 157 GASVSQFLGTMAPNFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFK 216
GASVSQFLGTMAPNFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFK
Sbjct: 181 GASVSQFLGTMAPNFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFK 240
Query: 217 LGFIVEKAGESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPKHVPASSGYN 276
LGFIVEKAGESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPKHVPASSGYN
Sbjct: 241 LGFIVEKAGESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPKHVPASSGYN 300
Query: 277 FRFAKYYKINGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCD 336
FRFAKYYKINGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCD
Sbjct: 301 FRFAKYYKINGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCD 360
Query: 337 WILLTFMNKNKVYSHKKFDKV-----------CTPSHPSG 365
WILLTFMNKNKVYSHKKFDK+ TP+ P G
Sbjct: 361 WILLTFMNKNKVYSHKKFDKMVDTPASEPAQASTPTDPKG 400
Score = 52.8 bits (125), Expect = 6e-07
Identities = 24/26 (92%), Positives = 26/26 (100%)
Query: 422 EQMVDTPASEPAQASTPTDPKGLAQL 447
++MVDTPASEPAQASTPTDPKGLAQL
Sbjct: 379 DKMVDTPASEPAQASTPTDPKGLAQL 404
>gi|28416921 purinergic receptor P2X2 isoform H [Homo sapiens]
Length = 379
Score = 727 bits (1876), Expect = 0.0
Identities = 348/356 (97%), Positives = 349/356 (98%), Gaps = 1/356 (0%)
Query: 92 VWDVEEYVKPPESIRVHNATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGW 151
+WD E K SIRVHNATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGW
Sbjct: 25 LWDYET-PKVIVSIRVHNATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGW 83
Query: 152 CPVEDGASVSQFLGTMAPNFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLY 211
CPVEDGASVSQFLGTMAPNFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLY
Sbjct: 84 CPVEDGASVSQFLGTMAPNFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLY 143
Query: 212 CPIFKLGFIVEKAGESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPKHVPA 271
CPIFKLGFIVEKAGESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPKHVPA
Sbjct: 144 CPIFKLGFIVEKAGESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPKHVPA 203
Query: 272 SSGYNFRFAKYYKINGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVG 331
SSGYNFRFAKYYKINGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVG
Sbjct: 204 SSGYNFRFAKYYKINGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVG 263
Query: 332 SFLCDWILLTFMNKNKVYSHKKFDKVCTPSHPSGSWPVTLARVLGQAPPEPGHRSEDQHP 391
SFLCDWILLTFMNKNKVYSHKKFDKVCTPSHPSGSWPVTLARVLGQAPPEPGHRSEDQHP
Sbjct: 264 SFLCDWILLTFMNKNKVYSHKKFDKVCTPSHPSGSWPVTLARVLGQAPPEPGHRSEDQHP 323
Query: 392 SPPSGQEGQQGAECGPAFPPLRPCPISAPSEQMVDTPASEPAQASTPTDPKGLAQL 447
SPPSGQEGQQGAECGPAFPPLRPCPISAPSEQMVDTPASEPAQASTPTDPKGLAQL
Sbjct: 324 SPPSGQEGQQGAECGPAFPPLRPCPISAPSEQMVDTPASEPAQASTPTDPKGLAQL 379
Score = 77.8 bits (190), Expect = 2e-14
Identities = 35/35 (100%), Positives = 35/35 (100%)
Query: 1 MAAAQPKYPAGATARRLARGCWSALWDYETPKVIV 35
MAAAQPKYPAGATARRLARGCWSALWDYETPKVIV
Sbjct: 1 MAAAQPKYPAGATARRLARGCWSALWDYETPKVIV 35
>gi|27881423 purinergic receptor P2X2 isoform I [Homo sapiens]
Length = 399
Score = 726 bits (1874), Expect = 0.0
Identities = 365/447 (81%), Positives = 372/447 (83%), Gaps = 48/447 (10%)
Query: 1 MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYV 60
MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVR ++RA +L
Sbjct: 1 MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVR------IHRAEKL---------- 44
Query: 61 FIVQKSYQESETGPESSIITKVKGITTSEHKVWDVEEYVKPPESIRVHNATCLSDADCVA 120
GP H + +V+ R
Sbjct: 45 -------PGERDGPREL-----------HHHQGQGDHHVRAQSVGR-------------- 72
Query: 121 GELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQFLGTMAPNFTILIKNSIH 180
G + GLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQFLGTMAPNFTILIKNSIH
Sbjct: 73 GGVREAPRGLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQFLGTMAPNFTILIKNSIH 132
Query: 181 YPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFKLGFIVEKAGESFTELAHKGGVIGV 240
YPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFKLGFIVEKAGESFTELAHKGGVIGV
Sbjct: 133 YPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFKLGFIVEKAGESFTELAHKGGVIGV 192
Query: 241 IINWDCDLDLPASECNPKYSFRRLDPKHVPASSGYNFRFAKYYKINGTTTRTLIKAYGIR 300
IINWDCDLDLPASECNPKYSFRRLDPKHVPASSGYNFRFAKYYKINGTTTRTLIKAYGIR
Sbjct: 193 IINWDCDLDLPASECNPKYSFRRLDPKHVPASSGYNFRFAKYYKINGTTTRTLIKAYGIR 252
Query: 301 IDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCDWILLTFMNKNKVYSHKKFDKVCTP 360
IDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCDWILLTFMNKNKVYSHKKFDKVCTP
Sbjct: 253 IDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCDWILLTFMNKNKVYSHKKFDKVCTP 312
Query: 361 SHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISAP 420
SHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISAP
Sbjct: 313 SHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISAP 372
Query: 421 SEQMVDTPASEPAQASTPTDPKGLAQL 447
SEQMVDTPASEPAQASTPTDPKGLAQL
Sbjct: 373 SEQMVDTPASEPAQASTPTDPKGLAQL 399
>gi|28416927 purinergic receptor P2X4 [Homo sapiens]
Length = 388
Score = 319 bits (817), Expect = 4e-87
Identities = 177/376 (47%), Positives = 238/376 (63%), Gaps = 41/376 (10%)
Query: 20 GCWSAL----WDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYVFIVQKSYQESETGPE 75
GC +AL ++Y+TP+++++R+R++G++ RAVQLLIL Y + +VF+ +K YQE+++
Sbjct: 3 GCCAALAAFLFEYDTPRIVLIRSRKVGLMNRAVQLLILAYVIGWVFVWEKGYQETDS-VV 61
Query: 76 SSIITKVKGITTSE-----HKVWDVEEYVKPPES----------IRVHNAT--------- 111
SS+ TKVKG+ + ++WDV +YV P + I N T
Sbjct: 62 SSVTTKVKGVAVTNTSKLGFRIWDVADYVIPAQEENSLFVMTNVILTMNQTQGLCPEIPD 121
Query: 112 ----CLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQ--FLG 165
C SDA C AG NG+ TGRCV + G KTCEV WCPVED V Q FL
Sbjct: 122 ATTVCKSDASCTAGSAGTHSNGVSTGRCVAF-NGSVKTCEVAAWCPVEDDTHVPQPAFLK 180
Query: 166 TMAPNFTILIKNSIHYPKFHFSKGNIADR-TDGYLKRCTFHEASDLYCPIFKLGFIVEKA 224
A NFT+L+KN+I YPKF+FSK NI T YLK C + +D +CPIF+LG IVE A
Sbjct: 181 A-AENFTLLVKNNIWYPKFNFSKRNILPNITTTYLKSCIYDAKTDPFCPIFRLGKIVENA 239
Query: 225 GESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPKHVP--ASSGYNFRFAKY 282
G SF ++A +GG++G+ +NWDC+LD AS C P+YSFRRLD + V S GYNFRFAKY
Sbjct: 240 GHSFQDMAVEGGIMGIQVNWDCNLDRAASLCLPRYSFRRLDTRDVEHNVSPGYNFRFAKY 299
Query: 283 YK-INGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCDWILLT 341
Y+ + G RTLIKAYGIR D+IV G+AGKF +IPT+IN+ + L +G+ + LCD I+L
Sbjct: 300 YRDLAGNEQRTLIKAYGIRFDIIVFGKAGKFDIIPTMINIGSGLALLGMATVLCDIIVLY 359
Query: 342 FMNKNKVYSHKKFDKV 357
M K Y KK+ V
Sbjct: 360 CMKKRLYYREKKYKYV 375
>gi|28416925 purinergic receptor P2X3 [Homo sapiens]
Length = 397
Score = 301 bits (770), Expect = 1e-81
Identities = 167/363 (46%), Positives = 222/363 (61%), Gaps = 30/363 (8%)
Query: 21 CWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYVFIVQKSYQESETGPESSIIT 80
C S + YET K +VV++ +G++ R VQLLI+ YFV +VF+ +K+YQ +T ESS++T
Sbjct: 3 CISDFFTYETTKSVVVKSWTIGIINRVVQLLIISYFVGWVFLHEKAYQVRDTAIESSVVT 62
Query: 81 KVKGITTSEHKVWDVEEYVKPPESIRV----------------------HNATCLSDADC 118
KVKG ++V DV +YV PP+ V C+SD+ C
Sbjct: 63 KVKGSGLYANRVMDVSDYVTPPQGTSVFVIITKMIVTENQMQGFCPESEEKYRCVSDSQC 122
Query: 119 VAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQFLGTMAPNFTILIKNS 178
G + G G+ TGRCV Y +TCE+ GWCP E +V + A NFTI IKNS
Sbjct: 123 --GPERLPGGGILTGRCVNY-SSVLRTCEIQGWCPTEVD-TVETPIMMEAENFTIFIKNS 178
Query: 179 IHYPKFHFSKGNIADR-TDGYLKRCTFHEASDLYCPIFKLGFIVEKAGESFTELAHKGGV 237
I +P F+F KGN+ T +K C FH D +CPI ++G +V+ AG+ F +LA GGV
Sbjct: 179 IRFPLFNFEKGNLLPNLTARDMKTCRFHPDKDPFCPILRVGDVVKFAGQDFAKLARTGGV 238
Query: 238 IGVIINWDCDLDLPASECNPKYSFRRLDP--KHVPASSGYNFRFAKYYKI-NGTTTRTLI 294
+G+ I W CDLD +C PKYSF RLD + S GYNFRFAKYYK+ NG+ RTL+
Sbjct: 239 LGIKIGWVCDLDKAWDQCIPKYSFTRLDSVSEKSSVSPGYNFRFAKYYKMENGSEYRTLL 298
Query: 295 KAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCDWILLTFMNKNKVYSHKKF 354
KA+GIR DV+V+G AGKF++IPTII+ A TSVGVG+ LCD ILL F+ Y KKF
Sbjct: 299 KAFGIRFDVLVYGNAGKFNIIPTIISSVAAFTSVGVGTVLCDIILLNFLKGADQYKAKKF 358
Query: 355 DKV 357
++V
Sbjct: 359 EEV 361
>gi|28416935 purinergic receptor P2X5 isoform B [Homo sapiens]
Length = 397
Score = 280 bits (716), Expect = 2e-75
Identities = 156/412 (37%), Positives = 232/412 (56%), Gaps = 40/412 (9%)
Query: 19 RGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYVFIVQKSYQESETGPESSI 78
+G +L+DY+T K ++ +N+++G+LYR +Q IL Y V +VF+++K YQ+ +T +S++
Sbjct: 7 KGLCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDTSLQSAV 66
Query: 79 ITKVKGIT---TSE--HKVWDVEEYVKPPESIRVHNATCLSDADCVAGELDMLGNGLRTG 133
ITKVKG+ TS+ ++WDV +YV P ++ + + C D+DC AGE GNG++TG
Sbjct: 67 ITKVKGVAFTNTSDLGQRIWDVADYVIPAQNEGIPDGACSKDSDCHAGEAVTAGNGVKTG 126
Query: 134 RCVPYYQGPSKTCEVFGWCPVEDGASVSQFLGTMAPNFTILIKNSIHYPKFHFSKGNIAD 193
RC+ TCE+F WCP+E + + A +FTI IKN I +PKF+FS +
Sbjct: 127 RCLRRENLARGTCEIFAWCPLETSSRPEEPFLKEAEDFTIFIKNHIRFPKFNFSNNVMDV 186
Query: 194 RTDGYLKRCTFHEASDLYCPIFKLGFIVEKAGESFTELAHKGGVIGVIINWDCDLDLPAS 253
+ +LK C F + YCPIF+LG ++ AG F ++A +GGVIG+ I W+CDLD AS
Sbjct: 187 KDRSFLKSCHFGPKNH-YCPIFRLGSVIRWAGSDFQDIALEGGVIGINIEWNCDLDKAAS 245
Query: 254 ECNPKYSFRRLDPK-HVPASSGYNFRFAKYYK-INGTTTRTLIKAYGIRIDVIVHGQAGK 311
EC+P YSF RLD K SSGYNFRFA+YY+ G RTL+KAYGIR DV+V+G+
Sbjct: 246 ECHPHYSFSRLDNKLSKSVSSGYNFRFARYYRDAAGVEFRTLMKAYGIRFDVMVNGK--- 302
Query: 312 FSLIPTIINLATALTSVGVGSFLCDWILLTFMNKNKVYSHKKFDKV-----CTPSHPSGS 366
G+F CD +L+ + K + Y KK+++V + +
Sbjct: 303 -------------------GAFFCDLVLIYLIKKREFYRDKKYEEVRGLEDSSQEAEDEA 343
Query: 367 WPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQ-----QGAECGPAFPPLR 413
+ L+ L P G + + PP + G G+ C P R
Sbjct: 344 SGLGLSEQLTSGPGLLGMPEQQELQEPPEAKRGSSSQKGNGSVCPQLLEPHR 395
>gi|28416933 purinergic receptor P2X5 isoform A [Homo sapiens]
Length = 422
Score = 274 bits (701), Expect = 1e-73
Identities = 161/437 (36%), Positives = 234/437 (53%), Gaps = 65/437 (14%)
Query: 19 RGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYVFIVQKSYQESETGPESSI 78
+G +L+DY+T K ++ +N+++G+LYR +Q IL Y V +VF+++K YQ+ +T +S++
Sbjct: 7 KGLCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDTSLQSAV 66
Query: 79 ITKVKGIT---TSE--HKVWDVEEYVKPPESIRVH------------------------N 109
ITKVKG+ TS+ ++WDV +YV P + V +
Sbjct: 67 ITKVKGVAFTNTSDLGQRIWDVADYVIPAQGENVFFVVTNLIVTPNQRQNVCAENEGIPD 126
Query: 110 ATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQFLGTMAP 169
C D+DC AGE GNG++TGRC+ TCE+F WCP+E + + A
Sbjct: 127 GACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLETSSRPEEPFLKEAE 186
Query: 170 NFTILIKNSIHYPKFHFSKGNIADRTD-GYLKRCTFHEASDLYCPIFKLGFIVEKAGESF 228
+FTI IKN I +PKF+FSK N+ D D +LK C F + YCPIF+LG ++ AG F
Sbjct: 187 DFTIFIKNHIRFPKFNFSKSNVMDVKDRSFLKSCHFGPKNH-YCPIFRLGSVIRWAGSDF 245
Query: 229 TELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPK-HVPASSGYNFRFAKYYK-IN 286
++A +GGVIG+ I W+CDLD ASEC+P YSF RLD K SSGYNFRFA+YY+
Sbjct: 246 QDIALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDNKLSKSVSSGYNFRFARYYRDAA 305
Query: 287 GTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCDWILLTFMNKN 346
G RTL+KAYGIR DV+V+G+ G+F CD +L+ + K
Sbjct: 306 GVEFRTLMKAYGIRFDVMVNGK----------------------GAFFCDLVLIYLIKKR 343
Query: 347 KVYSHKKFDKV-----CTPSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQ- 400
+ Y KK+++V + + + L+ L P G + + PP + G
Sbjct: 344 EFYRDKKYEEVRGLEDSSQEAEDEASGLGLSEQLTSGPGLLGMPEQQELQEPPEAKRGSS 403
Query: 401 ----QGAECGPAFPPLR 413
G+ C P R
Sbjct: 404 SQKGNGSVCPQLLEPHR 420
>gi|4505545 purinergic receptor P2X1 [Homo sapiens]
Length = 399
Score = 272 bits (695), Expect = 5e-73
Identities = 139/371 (37%), Positives = 221/371 (59%), Gaps = 34/371 (9%)
Query: 14 ARRLARGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYVFIVQKSYQESETG 73
ARR + L++Y+TP++++VRN+++GV++R +QL++L+Y + +VF+ +K YQ S +G
Sbjct: 2 ARRFQEELAAFLFEYDTPRMVLVRNKKVGVIFRLIQLVVLVYVIGWVFLYEKGYQTS-SG 60
Query: 74 PESSIITKVKGITTSE-----HKVWDVEEYVKPPE----------------------SIR 106
SS+ K+KG+ ++ +VWDV +YV P + +
Sbjct: 61 LISSVSVKLKGLAVTQLPGLGPQVWDVADYVFPAQGDNSFVVMTNFIVTPKQTQGYCAEH 120
Query: 107 VHNATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQ-FLG 165
C D+ C G+ G+RTG+CV + KTCE+FGWCPVE + + L
Sbjct: 121 PEGGICKEDSGCTPGKAKRKAQGIRTGKCVAF-NDTVKTCEIFGWCPVEVDDDIPRPALL 179
Query: 166 TMAPNFTILIKNSIHYPKFHFSKGNIADRTDG-YLKRCTFHEASDLYCPIFKLGFIVEKA 224
A NFT+ IKNSI +P+F ++ N+ + + ++K C FH+ CP+F+LG++V+++
Sbjct: 180 REAENFTLFIKNSISFPRFKVNRRNLVEEVNAAHMKTCLFHKTLHPLCPVFQLGYVVQES 239
Query: 225 GESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRL-DPKHVPASSGYNFRFAKYY 283
G++F+ LA KGGV+G+ I+W CDLD C P Y F L + K++ S G+NFRFA+++
Sbjct: 240 GQNFSTLAEKGGVVGITIDWHCDLDWHVRHCRPIYEFHGLYEEKNL--SPGFNFRFARHF 297
Query: 284 KINGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCDWILLTFM 343
NGT R L K +GIR D++V G+AGKF +IPT+ + + + GV + LCD +LL +
Sbjct: 298 VENGTNYRHLFKVFGIRFDILVDGKAGKFDIIPTMTTIGSGIGIFGVATVLCDLLLLHIL 357
Query: 344 NKNKVYSHKKF 354
K Y KKF
Sbjct: 358 PKRHYYKQKKF 368
>gi|157419148 purinergic receptor P2X6 isoform 1 [Homo sapiens]
Length = 441
Score = 261 bits (668), Expect = 7e-70
Identities = 160/440 (36%), Positives = 229/440 (52%), Gaps = 48/440 (10%)
Query: 10 AGATARRLARGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYVFIVQKSYQE 69
AG+ A W L DY+T K ++ RN R+G L R +Q I++Y V + + +K YQE
Sbjct: 8 AGSMGSPGATTGWGLL-DYKTEKYVMTRNWRVGALQRLLQFGIVVYVVGWALLAKKGYQE 66
Query: 70 SETGPESSIITKVKGITTSE-----HKVWDVEEYVKPPESIRVHN--------------- 109
+ P+ SIITK+KG++ ++ +++WDV ++VKPP+ V
Sbjct: 67 RDLEPQFSIITKLKGVSVTQIKELGNRLWDVADFVKPPQGENVFFLVTNFLVTPAQVQGR 126
Query: 110 ---------ATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVEDGASV 160
A C D DC GE +G++TG+CV + G +TCE++ WCPVE G
Sbjct: 127 CPEHPSVPLANCWVDEDCPEGEGGTHSHGVKTGQCV-VFNGTHRTCEIWSWCPVESGVVP 185
Query: 161 SQFLGTMAPNFTILIKNSIHYPKFHFSKGNIADRTDG-YLKRCTFHEASDLYCPIFKLGF 219
S+ L A NFT+ IKN++ + KF+FSK N + D Y K C + YCP+F++G
Sbjct: 186 SRPLLAQAQNFTLFIKNTVTFSKFNFSKSNALETWDPTYFKHCRYEPQFSPYCPVFRIGD 245
Query: 220 IVEKAGESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPKHVPASSGYNFRF 279
+V KAG +F +LA GG +G+ ++WDCDLD S C P YSF+ + YNFR
Sbjct: 246 LVAKAGGTFEDLALLGGSVGIRVHWDCDLDTGDSGCWPHYSFQLQE-------KSYNFRT 298
Query: 280 A-KYYKINGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCDWI 338
A +++ G RTL+K YGIR D++V GQAGKF LIPT + L T +GV +F CD +
Sbjct: 299 ATHWWEQPGVEARTLLKLYGIRFDILVTGQAGKFGLIPTAVTLGTGAAWLGVVTFFCDLL 358
Query: 339 LLTFMNKNKVYSHKKFDKVCTPSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQE 398
LL + Y K+++ P + S LA E RS P+P +
Sbjct: 359 LLYVDREAHFYWRTKYEEAKAPKATANSVWRELALASQARLAECLRRS--SAPAPTATAA 416
Query: 399 GQQGAECGPAFPPLRPCPIS 418
G Q P PCP S
Sbjct: 417 GSQ------TQTPGWPCPSS 430
>gi|227116341 purinergic receptor P2X6 isoform 2 [Homo sapiens]
Length = 415
Score = 234 bits (596), Expect = 2e-61
Identities = 141/391 (36%), Positives = 202/391 (51%), Gaps = 47/391 (12%)
Query: 59 YVFIVQKSYQESETGPESSIITKVKGITTSE-----HKVWDVEEYVKPPESIRVHN---- 109
+ + +K YQE + P+ SIITK+KG++ ++ +++WDV ++VKPP+ V
Sbjct: 30 WALLAKKGYQERDLEPQFSIITKLKGVSVTQIKELGNRLWDVADFVKPPQGENVFFLVTN 89
Query: 110 --------------------ATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVF 149
A C D DC GE +G++TG+CV + G +TCE++
Sbjct: 90 FLVTPAQVQGRCPEHPSVPLANCWVDEDCPEGEGGTHSHGVKTGQCV-VFNGTHRTCEIW 148
Query: 150 GWCPVEDGASVSQFLGTMAPNFTILIKNSIHYPKFHFSKGNIADRTDG-YLKRCTFHEAS 208
WCPVE G S+ L A NFT+ IKN++ + KF+FSK N + D Y K C +
Sbjct: 149 SWCPVESGVVPSRPLLAQAQNFTLFIKNTVTFSKFNFSKSNALETWDPTYFKHCRYEPQF 208
Query: 209 DLYCPIFKLGFIVEKAGESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPKH 268
YCP+F++G +V KAG +F +LA GG +G+ ++WDCDLD S C P YSF+ +
Sbjct: 209 SPYCPVFRIGDLVAKAGGTFEDLALLGGSVGIRVHWDCDLDTGDSGCWPHYSFQLQE--- 265
Query: 269 VPASSGYNFRFA-KYYKINGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTS 327
YNFR A +++ G RTL+K YGIR D++V GQAGKF LIPT + L T
Sbjct: 266 ----KSYNFRTATHWWEQPGVEARTLLKLYGIRFDILVTGQAGKFGLIPTAVTLGTGAAW 321
Query: 328 VGVGSFLCDWILLTFMNKNKVYSHKKFDKVCTPSHPSGSWPVTLARVLGQAPPEPGHRSE 387
+GV +F CD +LL + Y K+++ P + S LA E RS
Sbjct: 322 LGVVTFFCDLLLLYVDREAHFYWRTKYEEAKAPKATANSVWRELALASQARLAECLRRS- 380
Query: 388 DQHPSPPSGQEGQQGAECGPAFPPLRPCPIS 418
P+P + G Q P PCP S
Sbjct: 381 -SAPAPTATAAGSQ------TQTPGWPCPSS 404
>gi|29294631 purinergic receptor P2X7 [Homo sapiens]
Length = 595
Score = 218 bits (556), Expect = 7e-57
Identities = 135/376 (35%), Positives = 195/376 (51%), Gaps = 45/376 (11%)
Query: 23 SALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYVFIVQKSYQESETGPESSIITKV 82
S ++ YET KV +++ G + ++I Y V + + K YQ E SS+ TKV
Sbjct: 8 SDVFQYETNKVTRIQSMNYGTIKWFFHVIIFSY-VCFALVSDKLYQRKEP-VISSVHTKV 65
Query: 83 KGITTSE------------HKVWDVEEYVKPPES----------------------IRVH 108
KGI + H V+D +Y P +
Sbjct: 66 KGIAEVKEEIVENGVKKLVHSVFDTADYTFPLQGNSFFVMTNFLKTEGQEQRLCPEYPTR 125
Query: 109 NATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQ-FLGTM 167
C SD C G +D G++TGRCV Y+G KTCEV WCP+E + L
Sbjct: 126 RTLCSSDRGCKKGWMDPQSKGIQTGRCV-VYEGNQKTCEVSAWCPIEAVEEAPRPALLNS 184
Query: 168 APNFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFKLGFIVEKAGES 227
A NFT+LIKN+I +P +++ NI G CTFH+ + CPIF+LG I + G++
Sbjct: 185 AENFTVLIKNNIDFPGHNYTTRNILP---GLNITCTFHKTQNPQCPIFRLGDIFRETGDN 241
Query: 228 FTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPK--HVPASSGYNFRFAKYYKI 285
F+++A +GG++G+ I WDC+LD C PKYSFRRLD K +V GYNFR+AKYYK
Sbjct: 242 FSDVAIQGGIMGIEIYWDCNLDRWFHHCRPKYSFRRLDDKTTNVSLYPGYNFRYAKYYKE 301
Query: 286 NGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCDWILLTFMNK 345
N RTLIK +GIR D++V G GKF +I ++ + + L+ G+ + D+++ T+ +
Sbjct: 302 NNVEKRTLIKVFGIRFDILVFGTGGKFDIIQLVVYIGSTLSYFGLAAVFIDFLIDTY-SS 360
Query: 346 NKVYSH-KKFDKVCTP 360
N SH + K C P
Sbjct: 361 NCCRSHIYPWCKCCQP 376
>gi|28416937 purinergic receptor P2X5 isoform C [Homo sapiens]
Length = 178
Score = 117 bits (293), Expect = 2e-26
Identities = 60/166 (36%), Positives = 95/166 (57%), Gaps = 29/166 (17%)
Query: 19 RGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYVFIVQKSYQESETGPESSI 78
+G +L+DY+T K ++ +N+++G+LYR +Q IL Y V +VF+++K YQ+ +T +S++
Sbjct: 7 KGLCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDTSLQSAV 66
Query: 79 ITKVKGI---TTSE--HKVWDVEEYVKP------------------------PESIRVHN 109
ITKVKG+ TS+ ++WDV +YV P E+ + +
Sbjct: 67 ITKVKGVAFTNTSDLGQRIWDVADYVIPAQGENVFFVVTNLIVTPNQRQNVCAENEGIPD 126
Query: 110 ATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVE 155
C D+DC AGE GNG++TGRC+ TCE+F WCP+E
Sbjct: 127 GACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLE 172
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 38.1 bits (87), Expect = 0.016
Identities = 28/90 (31%), Positives = 36/90 (40%), Gaps = 18/90 (20%)
Query: 360 PSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISA 419
PS PS S P P PG PP+ Q G + ++ GPA PP +P ++
Sbjct: 296 PSLPSPSKPPI-------QQPTPG--------KPPAQQPGHEKSQPGPAKPPAQPSGLTK 340
Query: 420 PSEQM---VDTPASEPAQASTPTDPKGLAQ 446
P Q V P P P P G A+
Sbjct: 341 PLAQQPGTVKPPVQPPGTTKPPAQPLGPAK 370
Score = 30.8 bits (68), Expect = 2.6
Identities = 30/103 (29%), Positives = 36/103 (34%), Gaps = 27/103 (26%)
Query: 360 PSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISA 419
P+ PSG L + L Q P + P P G GPA PP +
Sbjct: 332 PAQPSG-----LTKPLAQQP------GTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEK 380
Query: 420 PSEQMVD------------TPASEPAQASTPTD----PKGLAQ 446
PS + TPA +P A PT PK LAQ
Sbjct: 381 PSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQ 423
Score = 29.6 bits (65), Expect = 5.8
Identities = 23/72 (31%), Positives = 28/72 (38%), Gaps = 5/72 (6%)
Query: 376 GQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFP-PLRPCPISAPSEQMVDTPASEPAQ 434
G A P P + PS G + GPA P P +P PS+Q P S
Sbjct: 485 GPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQ----PGSAKPS 540
Query: 435 ASTPTDPKGLAQ 446
A P+ K AQ
Sbjct: 541 AQQPSPAKPSAQ 552
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 38.1 bits (87), Expect = 0.016
Identities = 28/90 (31%), Positives = 36/90 (40%), Gaps = 18/90 (20%)
Query: 360 PSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISA 419
PS PS S P P PG PP+ Q G + ++ GPA PP +P ++
Sbjct: 296 PSLPSPSKPPI-------QQPTPG--------KPPAQQPGHEKSQPGPAKPPAQPSGLTK 340
Query: 420 PSEQM---VDTPASEPAQASTPTDPKGLAQ 446
P Q V P P P P G A+
Sbjct: 341 PLAQQPGTVKPPVQPPGTTKPPAQPLGPAK 370
Score = 30.8 bits (68), Expect = 2.6
Identities = 30/103 (29%), Positives = 36/103 (34%), Gaps = 27/103 (26%)
Query: 360 PSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISA 419
P+ PSG L + L Q P + P P G GPA PP +
Sbjct: 332 PAQPSG-----LTKPLAQQP------GTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEK 380
Query: 420 PSEQMVD------------TPASEPAQASTPTD----PKGLAQ 446
PS + TPA +P A PT PK LAQ
Sbjct: 381 PSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQ 423
Score = 29.6 bits (65), Expect = 5.8
Identities = 23/72 (31%), Positives = 28/72 (38%), Gaps = 5/72 (6%)
Query: 376 GQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFP-PLRPCPISAPSEQMVDTPASEPAQ 434
G A P P + PS G + GPA P P +P PS+Q P S
Sbjct: 485 GPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQ----PGSAKPS 540
Query: 435 ASTPTDPKGLAQ 446
A P+ K AQ
Sbjct: 541 AQQPSPAKPSAQ 552
>gi|54860079 nadrin isoform 1 [Homo sapiens]
Length = 881
Score = 37.0 bits (84), Expect = 0.036
Identities = 24/86 (27%), Positives = 38/86 (44%), Gaps = 7/86 (8%)
Query: 360 PSHPSGSWPVTLARVLGQ---APPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCP 416
P + +G P TL R + + APP+PG + P P GQ ++ P+ P P
Sbjct: 618 PHNAAGPSPHTLRRAVKKPAPAPPKPG----NPPPGHPGGQSSSGTSQHPPSLSPKPPTR 673
Query: 417 ISAPSEQMVDTPASEPAQASTPTDPK 442
+P Q P +P+ S + P+
Sbjct: 674 SPSPPTQHTGQPPGQPSAPSQLSAPR 699
Score = 32.0 bits (71), Expect = 1.2
Identities = 25/87 (28%), Positives = 31/87 (35%), Gaps = 15/87 (17%)
Query: 360 PSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISA 419
P HP G + Q PP + + PSPP+ GQ P P P +SA
Sbjct: 648 PGHPGGQ----SSSGTSQHPPSLSPKPPTRSPSPPTQHTGQ------PPGQPSAPSQLSA 697
Query: 420 P-----SEQMVDTPASEPAQASTPTDP 441
P S + P P Q T P
Sbjct: 698 PRRYSSSLSPIQAPNHPPPQPPTQATP 724
>gi|54860105 nadrin isoform 2 [Homo sapiens]
Length = 803
Score = 37.0 bits (84), Expect = 0.036
Identities = 24/86 (27%), Positives = 38/86 (44%), Gaps = 7/86 (8%)
Query: 360 PSHPSGSWPVTLARVLGQ---APPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCP 416
P + +G P TL R + + APP+PG + P P GQ ++ P+ P P
Sbjct: 540 PHNAAGPSPHTLRRAVKKPAPAPPKPG----NPPPGHPGGQSSSGTSQHPPSLSPKPPTR 595
Query: 417 ISAPSEQMVDTPASEPAQASTPTDPK 442
+P Q P +P+ S + P+
Sbjct: 596 SPSPPTQHTGQPPGQPSAPSQLSAPR 621
Score = 32.0 bits (71), Expect = 1.2
Identities = 25/87 (28%), Positives = 31/87 (35%), Gaps = 15/87 (17%)
Query: 360 PSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISA 419
P HP G + Q PP + + PSPP+ GQ P P P +SA
Sbjct: 570 PGHPGGQ----SSSGTSQHPPSLSPKPPTRSPSPPTQHTGQ------PPGQPSAPSQLSA 619
Query: 420 P-----SEQMVDTPASEPAQASTPTDP 441
P S + P P Q T P
Sbjct: 620 PRRYSSSLSPIQAPNHPPPQPPTQATP 646
>gi|23397666 transcriptional co-repressor Sin3A [Homo sapiens]
Length = 1273
Score = 36.6 bits (83), Expect = 0.048
Identities = 20/58 (34%), Positives = 27/58 (46%), Gaps = 3/58 (5%)
Query: 381 EPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISAPSEQMVDTPASEPAQASTP 438
+P + QHPS PS Q A+ P PP + +S PS+ TPAS+ P
Sbjct: 217 QPQPQPPPQHPSQPSAQSAPAPAQPAPQPPPAK---VSKPSQLQAHTPASQQTPPLPP 271
>gi|223941785 transcriptional co-repressor Sin3A [Homo sapiens]
Length = 1273
Score = 36.6 bits (83), Expect = 0.048
Identities = 20/58 (34%), Positives = 27/58 (46%), Gaps = 3/58 (5%)
Query: 381 EPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISAPSEQMVDTPASEPAQASTP 438
+P + QHPS PS Q A+ P PP + +S PS+ TPAS+ P
Sbjct: 217 QPQPQPPPQHPSQPSAQSAPAPAQPAPQPPPAK---VSKPSQLQAHTPASQQTPPLPP 271
>gi|223941782 transcriptional co-repressor Sin3A [Homo sapiens]
Length = 1273
Score = 36.6 bits (83), Expect = 0.048
Identities = 20/58 (34%), Positives = 27/58 (46%), Gaps = 3/58 (5%)
Query: 381 EPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISAPSEQMVDTPASEPAQASTP 438
+P + QHPS PS Q A+ P PP + +S PS+ TPAS+ P
Sbjct: 217 QPQPQPPPQHPSQPSAQSAPAPAQPAPQPPPAK---VSKPSQLQAHTPASQQTPPLPP 271
>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
Length = 1094
Score = 36.2 bits (82), Expect = 0.062
Identities = 27/78 (34%), Positives = 36/78 (46%), Gaps = 11/78 (14%)
Query: 379 PPEPGHRSEDQHPSPPS--GQEGQQGAECGPA-----FPPLRPCPISAP---SEQMVDTP 428
PP+P + + Q P PP+ G EG A C P P L P P E+ +
Sbjct: 522 PPKPERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSPS 581
Query: 429 ASEPAQASTPT-DPKGLA 445
+ +Q+ TPT PKGLA
Sbjct: 582 SGYSSQSGTPTLPPKGLA 599
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 35.8 bits (81), Expect = 0.081
Identities = 27/86 (31%), Positives = 36/86 (41%), Gaps = 5/86 (5%)
Query: 357 VCTPSHPSGSWPVT-LARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPC 415
V P P S PV+ A QAPP PSPP+ A P PP
Sbjct: 673 VQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP---- 728
Query: 416 PISAPSEQMVDTPASEPAQASTPTDP 441
P++AP Q+ +P + P + + T P
Sbjct: 729 PLAAPPLQVPPSPPASPPMSPSATPP 754
Score = 29.3 bits (64), Expect = 7.6
Identities = 27/88 (30%), Positives = 31/88 (35%), Gaps = 3/88 (3%)
Query: 360 PSHPSGSWPVT-LARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPC-PI 417
P P S P++ A QAPP PSPP+ A P PPL P+
Sbjct: 707 PPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPL 766
Query: 418 SAPSEQMVDTPASEPAQASTPTDPKGLA 445
P P S P P P LA
Sbjct: 767 QVPPSPPASLPMS-PLAKPPPQAPPALA 793
>gi|155030236 ribonuclease III, nuclear isoform 2 [Homo sapiens]
Length = 1337
Score = 35.8 bits (81), Expect = 0.081
Identities = 23/79 (29%), Positives = 29/79 (36%), Gaps = 19/79 (24%)
Query: 360 PSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISA 419
P PS P+ + PP P H+ P PP C P PP PCP +
Sbjct: 84 PMPPSAQGPLPPCPI---RPPFPNHQMRHPFPVPP----------CFPPMPPPMPCPNNP 130
Query: 420 PSEQMVDTPASEPAQASTP 438
P P + P Q + P
Sbjct: 131 P------VPGAPPGQGTFP 143
>gi|155030234 ribonuclease III, nuclear isoform 1 [Homo sapiens]
Length = 1374
Score = 35.8 bits (81), Expect = 0.081
Identities = 23/79 (29%), Positives = 29/79 (36%), Gaps = 19/79 (24%)
Query: 360 PSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISA 419
P PS P+ + PP P H+ P PP C P PP PCP +
Sbjct: 84 PMPPSAQGPLPPCPI---RPPFPNHQMRHPFPVPP----------CFPPMPPPMPCPNNP 130
Query: 420 PSEQMVDTPASEPAQASTP 438
P P + P Q + P
Sbjct: 131 P------VPGAPPGQGTFP 143
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 35.4 bits (80), Expect = 0.11
Identities = 27/83 (32%), Positives = 33/83 (39%), Gaps = 5/83 (6%)
Query: 357 VCTPSHPSGSWPVT-LARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPC 415
V P P S PV+ A QAPP PSPP+ A P PP
Sbjct: 448 VQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP---- 503
Query: 416 PISAPSEQMVDTPASEPAQASTP 438
P++AP Q+ P P +TP
Sbjct: 504 PLAAPPLQLAKPPPQAPPALATP 526
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 35.4 bits (80), Expect = 0.11
Identities = 27/83 (32%), Positives = 33/83 (39%), Gaps = 5/83 (6%)
Query: 357 VCTPSHPSGSWPVT-LARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPC 415
V P P S PV+ A QAPP PSPP+ A P PP
Sbjct: 409 VQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP---- 464
Query: 416 PISAPSEQMVDTPASEPAQASTP 438
P++AP Q+ P P +TP
Sbjct: 465 PLAAPPLQLAKPPPQAPPALATP 487
Score = 30.0 bits (66), Expect = 4.4
Identities = 21/81 (25%), Positives = 33/81 (40%), Gaps = 2/81 (2%)
Query: 361 SHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISAP 420
S P+ S P AR +AP P + Q + PA PL P++ P
Sbjct: 241 SSPARSGPS--ARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATP 298
Query: 421 SEQMVDTPASEPAQASTPTDP 441
S +P++ P+ + P+ P
Sbjct: 299 SPSAPPSPSAPPSLQTLPSPP 319
>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
Length = 3230
Score = 35.4 bits (80), Expect = 0.11
Identities = 23/83 (27%), Positives = 31/83 (37%)
Query: 363 PSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISAPSE 422
PS + P+ VL +P + Q P P G A P P P+ APS
Sbjct: 1600 PSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSS 1659
Query: 423 QMVDTPASEPAQASTPTDPKGLA 445
PA P+ +P + LA
Sbjct: 1660 TQTMLPAPVPSPLPSPASTQTLA 1682
>gi|39812378 RAN binding protein 9 [Homo sapiens]
Length = 729
Score = 34.7 bits (78), Expect = 0.18
Identities = 31/86 (36%), Positives = 34/86 (39%), Gaps = 8/86 (9%)
Query: 368 PVTLARVLGQAPPEPGHRSEDQHPS-PPSGQEGQQGAECGPA----FPPLRPCPISA--- 419
P LA V G P P S P+ P G G +G A PP P P +A
Sbjct: 24 PAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLGAAAAALLLHPPPPPPPATAAPP 83
Query: 420 PSEQMVDTPASEPAQASTPTDPKGLA 445
P PAS A AS P P GLA
Sbjct: 84 PPPPPPPPPASAAAPASGPPAPPGLA 109
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.137 0.434
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,534,228
Number of Sequences: 37866
Number of extensions: 995240
Number of successful extensions: 5323
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 49
Number of HSP's successfully gapped in prelim test: 177
Number of HSP's that attempted gapping in prelim test: 4852
Number of HSP's gapped (non-prelim): 577
length of query: 447
length of database: 18,247,518
effective HSP length: 105
effective length of query: 342
effective length of database: 14,271,588
effective search space: 4880883096
effective search space used: 4880883096
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.