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Search of human proteins with 7661788
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7661788 mediator complex subunit 4 [Homo sapiens]
(270 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7661788 mediator complex subunit 4 [Homo sapiens] 531 e-151
gi|16262452 cingulin [Homo sapiens] 42 6e-04
gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens] 42 7e-04
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 41 0.001
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 41 0.001
gi|145312241 differentially expressed in FDCP 6 homolog [Homo sa... 40 0.003
gi|154800489 ER lipid raft associated 1 [Homo sapiens] 39 0.004
gi|154800487 ER lipid raft associated 1 [Homo sapiens] 39 0.004
gi|55741447 pleckstrin homology domain containing, family H (wit... 39 0.005
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 39 0.006
gi|188497714 transmembrane and coiled-coil domain family 3 [Homo... 39 0.006
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] 38 0.008
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 38 0.008
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] 38 0.008
gi|8923243 palmdelphin [Homo sapiens] 38 0.011
gi|32698866 spindle pole body component 24 homolog [Homo sapiens] 38 0.011
gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens] 37 0.014
gi|38044112 restin isoform b [Homo sapiens] 37 0.018
gi|4506751 restin isoform a [Homo sapiens] 37 0.018
gi|87298937 centrosomal protein 110kDa [Homo sapiens] 37 0.018
gi|157738667 FYVE and coiled-coil domain containing 1 [Homo sapi... 37 0.024
gi|81295809 pericentrin [Homo sapiens] 37 0.024
gi|239787821 syncoilin, intermediate filament 1 isoform 2 [Homo ... 36 0.040
gi|63252904 tropomyosin 1 alpha chain isoform 6 [Homo sapiens] 36 0.040
gi|39930479 DIX domain containing 1 isoform b [Homo sapiens] 36 0.040
gi|83816971 DIX domain containing 1 isoform a [Homo sapiens] 36 0.040
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] 36 0.040
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 36 0.040
gi|221219020 NYD-SP11 protein [Homo sapiens] 35 0.053
gi|190194355 p90 autoantigen [Homo sapiens] 35 0.053
>gi|7661788 mediator complex subunit 4 [Homo sapiens]
Length = 270
Score = 531 bits (1368), Expect = e-151
Identities = 270/270 (100%), Positives = 270/270 (100%)
Query: 1 MAASSSGEKEKERLGGGLGVAGGNSTRERLLSALEDLEVLSRELIEMLAISRNQKLLQAG 60
MAASSSGEKEKERLGGGLGVAGGNSTRERLLSALEDLEVLSRELIEMLAISRNQKLLQAG
Sbjct: 1 MAASSSGEKEKERLGGGLGVAGGNSTRERLLSALEDLEVLSRELIEMLAISRNQKLLQAG 60
Query: 61 EENQVLELLIHRDGEFQELMKLALNQGKIHHEMQVLEKEVEKRDSDIQQLQKQLKEAEQI 120
EENQVLELLIHRDGEFQELMKLALNQGKIHHEMQVLEKEVEKRDSDIQQLQKQLKEAEQI
Sbjct: 61 EENQVLELLIHRDGEFQELMKLALNQGKIHHEMQVLEKEVEKRDSDIQQLQKQLKEAEQI 120
Query: 121 LATAVYQAKEKLKSIEKARKGAISSEEIIKYAHRISASNAVCAPLTWVPGDPRRPYPTDL 180
LATAVYQAKEKLKSIEKARKGAISSEEIIKYAHRISASNAVCAPLTWVPGDPRRPYPTDL
Sbjct: 121 LATAVYQAKEKLKSIEKARKGAISSEEIIKYAHRISASNAVCAPLTWVPGDPRRPYPTDL 180
Query: 181 EMRSGLLGQMNNPSTNGVNGHLPGDALAAGRLPDVLAPQYPWQSNDMSMNMLPPNHSSDF 240
EMRSGLLGQMNNPSTNGVNGHLPGDALAAGRLPDVLAPQYPWQSNDMSMNMLPPNHSSDF
Sbjct: 181 EMRSGLLGQMNNPSTNGVNGHLPGDALAAGRLPDVLAPQYPWQSNDMSMNMLPPNHSSDF 240
Query: 241 LLEPPGHNKENEDDVEIMSTDSSSSSSESD 270
LLEPPGHNKENEDDVEIMSTDSSSSSSESD
Sbjct: 241 LLEPPGHNKENEDDVEIMSTDSSSSSSESD 270
>gi|16262452 cingulin [Homo sapiens]
Length = 1203
Score = 42.0 bits (97), Expect = 6e-04
Identities = 45/177 (25%), Positives = 79/177 (44%), Gaps = 38/177 (21%)
Query: 20 VAGGNSTRERLLSALEDLEVLSRELIEMLAISRNQK--------------------LLQA 59
V GG + RL L+ LE ++L E L S+ ++ L +
Sbjct: 753 VDGGEAVEARLRDKLQRLEAEKQQLEEALNASQEEEGSLAAAKRALEARLEEAQRGLARL 812
Query: 60 GEENQVLELLIHRDGEFQELMKLALNQGKIHHEMQVLE-------KEVEKRDSD----IQ 108
G+E Q L + +G+ +E+++ + ++ + ++L+ KE+EK D +Q
Sbjct: 813 GQEQQTLNRALEEEGKQREVLRRG--KAELEEQKRLLDRTVDRLNKELEKIGEDSKQALQ 870
Query: 109 QLQKQLKE----AEQILATAVYQAKEKLKSIEKARKG-AISSEEIIKYAHRISASNA 160
QLQ QL++ A + +A A QAK+ EK G + +EI + + AS A
Sbjct: 871 QLQAQLEDYKEKARREVADAQRQAKDWASEAEKTSGGLSRLQDEIQRLRQALQASQA 927
>gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]
Length = 1417
Score = 41.6 bits (96), Expect = 7e-04
Identities = 31/119 (26%), Positives = 59/119 (49%), Gaps = 4/119 (3%)
Query: 36 DLEVLSRELIEM--LAISRNQKLLQAGEENQVLELLI--HRDGEFQELMKLALNQGKIHH 91
++E +EL+EM RN +L Q + L++ I HR Q+++KL K
Sbjct: 1117 EIEDKKQELLEMDQALKERNWELKQRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSEL 1176
Query: 92 EMQVLEKEVEKRDSDIQQLQKQLKEAEQILATAVYQAKEKLKSIEKARKGAISSEEIIK 150
E++ K++E + +Q ++QL+E E I+ + + K IE+ ++ E ++K
Sbjct: 1177 ELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEMESVMK 1235
Score = 33.1 bits (74), Expect = 0.26
Identities = 29/132 (21%), Positives = 62/132 (46%), Gaps = 12/132 (9%)
Query: 28 ERLLSALEDLEVLSRE-------LIEMLAISRNQKL-----LQAGEENQVLELLIHRDGE 75
ERL S LED++ LS+E L E L S+ ++ +QA + E+ ++
Sbjct: 1284 ERLSSELEDMKQLSKEKDAHGNHLAEELGASKVREAHLEARMQAEIKKLSAEVESLKEAY 1343
Query: 76 FQELMKLALNQGKIHHEMQVLEKEVEKRDSDIQQLQKQLKEAEQILATAVYQAKEKLKSI 135
E++ N K + V++ + +++ + +L+EA+ ++ Q +++ + I
Sbjct: 1344 HMEMISHQENHAKWKISADSQKSSVQQLNEQLEKAKLELEEAQDTVSNLHQQVQDRNEVI 1403
Query: 136 EKARKGAISSEE 147
E A + ++ E
Sbjct: 1404 EAANEALLTKGE 1415
Score = 30.4 bits (67), Expect = 1.7
Identities = 28/127 (22%), Positives = 60/127 (47%), Gaps = 18/127 (14%)
Query: 29 RLLSALEDLEVLSRELIEMLAISRNQKLLQAGEENQVLELLIHRDGEFQELMKLALNQGK 88
+L LE E+ +E + + S N KL A E+ + E ++ ++ +
Sbjct: 1166 KLEGTLEKSELELKECNKQIE-SLNDKLQNAKEQLREKEFIMLQNEQ------------- 1211
Query: 89 IHHEMQVLEKEVEKRDSDIQQLQKQLKEAEQILATAVYQAKEKLKSIEKARKGAISSE-E 147
E+ L+KE+E+ +++++ +KE EQ +AT +A + + + R+ +S E
Sbjct: 1212 ---EISQLKKEIERTQQRMKEMESVMKEQEQYIATQYKEAIDLGQELRLTREQVQNSHTE 1268
Query: 148 IIKYAHR 154
+ + H+
Sbjct: 1269 LAEARHQ 1275
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 41.2 bits (95), Expect = 0.001
Identities = 38/138 (27%), Positives = 74/138 (53%), Gaps = 6/138 (4%)
Query: 8 EKEKERLGGGLGVAGGNSTR-ERLLSALEDLEVLSRELIEMLAISRNQKLLQAGEENQVL 66
E EKE+L GL + + + ERL + + L++ ++ L + L S N+K+ Q E Q L
Sbjct: 731 ESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENS-NKKIQQLESELQDL 789
Query: 67 ELLIHRDGEFQELMKLALNQ-GKIHHEMQVLEKEVEKRDSDIQQLQKQ---LKEAEQILA 122
E+ + E +K++ + ++ E + LE+E + + D +QL+K+ L++ +I
Sbjct: 790 EMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKD 849
Query: 123 TAVYQAKEKLKSIEKARK 140
T + + K+ ++EK K
Sbjct: 850 TTLEENNVKIGNLEKENK 867
Score = 36.6 bits (83), Expect = 0.024
Identities = 31/153 (20%), Positives = 73/153 (47%), Gaps = 9/153 (5%)
Query: 8 EKEKERLGGGLGVAGGNSTRERLLSALEDLEVLSRELI-EMLAISRNQKLLQAGEENQVL 66
EKE +RL + + +E+ +L++ + LS++L+ E + + + L+ E Q+
Sbjct: 497 EKENQRLSKKVEILENEIVQEK--QSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQI- 553
Query: 67 ELLIHRDGEFQELMKLALNQGKIHHEMQVLEKEVEKRDSDIQQLQKQLKEAEQILATAVY 126
++L + + + + +I E +V K++EK + + L + +KE L+ +
Sbjct: 554 KILEQENEHLNQTVSSLRQRSQISAEARV--KDIEKEN---KILHESIKETSSKLSKIEF 608
Query: 127 QAKEKLKSIEKARKGAISSEEIIKYAHRISASN 159
+ ++ K +E ++ +EE+ H + N
Sbjct: 609 EKRQIKKELEHYKEKGERAEELENELHHLEKEN 641
Score = 34.3 bits (77), Expect = 0.12
Identities = 33/125 (26%), Positives = 60/125 (48%), Gaps = 8/125 (6%)
Query: 28 ERLLSALEDLEVLSRELIEMLAISRNQKLLQAGEEN--QVLELLIHRDGEFQELMKLALN 85
E L ++E L ++M + K L++ +E + LELL F++ +L ++
Sbjct: 701 EENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELL---KASFKKTERLEVS 757
Query: 86 QGKIHHEMQVLEKEVEKRDSDIQQLQKQLKEAE---QILATAVYQAKEKLKSIEKARKGA 142
+ E Q L+K +E + IQQL+ +L++ E Q L + + K K +E+ K
Sbjct: 758 YQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKEN 817
Query: 143 ISSEE 147
S E+
Sbjct: 818 KSLEQ 822
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 41.2 bits (95), Expect = 0.001
Identities = 38/138 (27%), Positives = 74/138 (53%), Gaps = 6/138 (4%)
Query: 8 EKEKERLGGGLGVAGGNSTR-ERLLSALEDLEVLSRELIEMLAISRNQKLLQAGEENQVL 66
E EKE+L GL + + + ERL + + L++ ++ L + L S N+K+ Q E Q L
Sbjct: 731 ESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENS-NKKIQQLESELQDL 789
Query: 67 ELLIHRDGEFQELMKLALNQ-GKIHHEMQVLEKEVEKRDSDIQQLQKQ---LKEAEQILA 122
E+ + E +K++ + ++ E + LE+E + + D +QL+K+ L++ +I
Sbjct: 790 EMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKD 849
Query: 123 TAVYQAKEKLKSIEKARK 140
T + + K+ ++EK K
Sbjct: 850 TTLEENNVKIGNLEKENK 867
Score = 36.6 bits (83), Expect = 0.024
Identities = 31/153 (20%), Positives = 73/153 (47%), Gaps = 9/153 (5%)
Query: 8 EKEKERLGGGLGVAGGNSTRERLLSALEDLEVLSRELI-EMLAISRNQKLLQAGEENQVL 66
EKE +RL + + +E+ +L++ + LS++L+ E + + + L+ E Q+
Sbjct: 497 EKENQRLSKKVEILENEIVQEK--QSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQI- 553
Query: 67 ELLIHRDGEFQELMKLALNQGKIHHEMQVLEKEVEKRDSDIQQLQKQLKEAEQILATAVY 126
++L + + + + +I E +V K++EK + + L + +KE L+ +
Sbjct: 554 KILEQENEHLNQTVSSLRQRSQISAEARV--KDIEKEN---KILHESIKETSSKLSKIEF 608
Query: 127 QAKEKLKSIEKARKGAISSEEIIKYAHRISASN 159
+ ++ K +E ++ +EE+ H + N
Sbjct: 609 EKRQIKKELEHYKEKGERAEELENELHHLEKEN 641
Score = 34.3 bits (77), Expect = 0.12
Identities = 33/125 (26%), Positives = 60/125 (48%), Gaps = 8/125 (6%)
Query: 28 ERLLSALEDLEVLSRELIEMLAISRNQKLLQAGEEN--QVLELLIHRDGEFQELMKLALN 85
E L ++E L ++M + K L++ +E + LELL F++ +L ++
Sbjct: 701 EENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELL---KASFKKTERLEVS 757
Query: 86 QGKIHHEMQVLEKEVEKRDSDIQQLQKQLKEAE---QILATAVYQAKEKLKSIEKARKGA 142
+ E Q L+K +E + IQQL+ +L++ E Q L + + K K +E+ K
Sbjct: 758 YQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKEN 817
Query: 143 ISSEE 147
S E+
Sbjct: 818 KSLEQ 822
>gi|145312241 differentially expressed in FDCP 6 homolog [Homo
sapiens]
Length = 631
Score = 39.7 bits (91), Expect = 0.003
Identities = 30/87 (34%), Positives = 52/87 (59%), Gaps = 6/87 (6%)
Query: 58 QAGEENQVLELLIHRDGEFQELMKLALNQGKIHHEMQVLEKEVEKRDSDIQQLQK----Q 113
+A +E ++L L ++ + ++L +L L Q ++L++E E+R S ++LQ+ Q
Sbjct: 340 RAAKEEELLRLQQLQEEKERKLQELELLQEAQRQAERLLQEEEERRRSQHRELQQALEGQ 399
Query: 114 LKEAEQILATAVYQAKEKLKSIEKARK 140
L+EAEQ A A QA+ +LK E AR+
Sbjct: 400 LREAEQ--ARASMQAEMELKEEEAARQ 424
Score = 33.5 bits (75), Expect = 0.20
Identities = 45/186 (24%), Positives = 81/186 (43%), Gaps = 23/186 (12%)
Query: 27 RERLLSALEDLEVLSRELIEMLAISRNQKLLQAGEEN--QVLELLIHRDG-------EFQ 77
++RL AL+ LEV +R E + I++ +LL+ EE Q+++L ++ E +
Sbjct: 435 QQRLQEALQ-LEVKARRDEESVRIAQT-RLLEEEEEKLKQLMQLKEEQERYIERAQQEKE 492
Query: 78 ELMKLALNQGKIHHEMQVLEKEV----EKRDSDIQQLQKQLKEAEQILATAVYQAKEKLK 133
EL + Q + + Q +EV ++ D D++ Q++L++A + Q +
Sbjct: 493 ELQQEMAQQSRSLQQAQQQLEEVRQNRQRADEDVEAAQRKLRQASTNVKHWNVQMNRLMH 552
Query: 134 SIEKARKGAISSEEIIKY-----AHRISASNAVCAPLTWVPGDPRRPYPTDLEMRSGLLG 188
IE K ++S + AHR S+ + W R P P E + L G
Sbjct: 553 PIEPGDKRPVTSSSFSGFQPPLLAHRDSSLKRL---TRWGSQGNRTPSPNSNEQQKSLNG 609
Query: 189 QMNNPS 194
P+
Sbjct: 610 GDEAPA 615
>gi|154800489 ER lipid raft associated 1 [Homo sapiens]
Length = 348
Score = 39.3 bits (90), Expect = 0.004
Identities = 32/131 (24%), Positives = 66/131 (50%), Gaps = 11/131 (8%)
Query: 8 EKEKERLGGGLGVAGGNSTRERLLSALE-DLEVLSRELIEMLAISRNQKLLQAGEENQVL 66
+K+ + GL + T+ ++ A+ + E++ E ++L ++ QK+++ E +
Sbjct: 155 QKDLNLMAPGLTIQAVRVTKPKIPEAIRRNFELMEAEKTKLLIAAQKQKVVEKEAETERK 214
Query: 67 ELLIHRDGEFQELMKLALNQGKIHHEMQVLEKEVEKRDSDIQQLQKQLKEAEQILATAVY 126
+ +I E +++ ++A KI + +V+EKE EKR S+I+ +E + A A Y
Sbjct: 215 KAVI----EAEKIAQVA----KIRFQQKVMEKETEKRISEIEDAAFLAREKAK--ADAEY 264
Query: 127 QAKEKLKSIEK 137
A K + K
Sbjct: 265 YAAHKYATSNK 275
>gi|154800487 ER lipid raft associated 1 [Homo sapiens]
Length = 348
Score = 39.3 bits (90), Expect = 0.004
Identities = 32/131 (24%), Positives = 66/131 (50%), Gaps = 11/131 (8%)
Query: 8 EKEKERLGGGLGVAGGNSTRERLLSALE-DLEVLSRELIEMLAISRNQKLLQAGEENQVL 66
+K+ + GL + T+ ++ A+ + E++ E ++L ++ QK+++ E +
Sbjct: 155 QKDLNLMAPGLTIQAVRVTKPKIPEAIRRNFELMEAEKTKLLIAAQKQKVVEKEAETERK 214
Query: 67 ELLIHRDGEFQELMKLALNQGKIHHEMQVLEKEVEKRDSDIQQLQKQLKEAEQILATAVY 126
+ +I E +++ ++A KI + +V+EKE EKR S+I+ +E + A A Y
Sbjct: 215 KAVI----EAEKIAQVA----KIRFQQKVMEKETEKRISEIEDAAFLAREKAK--ADAEY 264
Query: 127 QAKEKLKSIEK 137
A K + K
Sbjct: 265 YAAHKYATSNK 275
>gi|55741447 pleckstrin homology domain containing, family H (with
MyTH4 domain) member 1 [Homo sapiens]
Length = 1364
Score = 38.9 bits (89), Expect = 0.005
Identities = 28/101 (27%), Positives = 52/101 (51%), Gaps = 8/101 (7%)
Query: 42 RELIEMLAISRNQKLLQAGEENQVLELLIHRDGEFQELMKLAL-----NQGKIHHEMQVL 96
REL+ Q+LL+A + + E + G +E +KL+ ++G +H + Q L
Sbjct: 36 RELLADKMQELEQRLLEAEQRAENAETQV---GVMEEKVKLSNLKNVDSEGSLHRKYQEL 92
Query: 97 EKEVEKRDSDIQQLQKQLKEAEQILATAVYQAKEKLKSIEK 137
K ++ +D I QL+ QL++ +Q+ A +EK I++
Sbjct: 93 LKAIKGKDELISQLEAQLEKQKQMRAEEAKTVQEKAAKIKE 133
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 38.5 bits (88), Expect = 0.006
Identities = 38/159 (23%), Positives = 72/159 (45%), Gaps = 19/159 (11%)
Query: 6 SGEKEKERLGGGLGVAGGNSTRERLLSALEDLEVLSRELIEMLAISRNQKLLQAGEENQV 65
S ++ L GG VA ++ + L+++E EL E+ S +L + EE
Sbjct: 1290 SHSEDASALQGGTSVA-------QIKAQLKEIEAEKVEL-ELKVSSTTSELTKKSEEVFQ 1341
Query: 66 LELLIHRDGEFQELMKLALNQGKIHHE--MQVLE---------KEVEKRDSDIQQLQKQL 114
L+ I++ G E +K ++ ++H E Q LE + + + + +LQK +
Sbjct: 1342 LQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHLRELQPKLDELQKLI 1401
Query: 115 KEAEQILATAVYQAKEKLKSIEKARKGAISSEEIIKYAH 153
+ E+ ++ Q EK ++ K + I E++IK H
Sbjct: 1402 SKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALH 1440
Score = 38.1 bits (87), Expect = 0.008
Identities = 37/139 (26%), Positives = 64/139 (46%), Gaps = 8/139 (5%)
Query: 9 KEKERLGGGLGVAGGNS--TRERLLSALEDLEVLSRELIEMLAISRNQKLLQAGEENQVL 66
+EK+ L G L N T ++L A +++E + +E + A S+ QK+L+ EEN L
Sbjct: 1641 QEKQELYGKLRSTEANKKETEKQLQEAEQEMEEM-KEKMRKFAKSKQQKILELEEENDRL 1699
Query: 67 ELLIHRDGE-FQELMKLAL-NQGKIHHEMQVLEKEVEKRDSDIQQLQKQ---LKEAEQIL 121
+H G+ +E M+ L + + E++ ++ E E Q L + L E Q L
Sbjct: 1700 RAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDL 1759
Query: 122 ATAVYQAKEKLKSIEKARK 140
+ K ++E K
Sbjct: 1760 KHQIEGNVSKQANLEATEK 1778
Score = 33.9 bits (76), Expect = 0.15
Identities = 34/126 (26%), Positives = 60/126 (47%), Gaps = 13/126 (10%)
Query: 28 ERLLSALEDLEVLSRELIEMLAISRNQ-KLLQA--GEENQVLELLIHR-----DGEFQEL 79
E L+A E + L +++ + L NQ LLQA E +++ LI DG+ L
Sbjct: 1081 EEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNTDASDGDSVAL 1140
Query: 80 MKLALN-----QGKIHHEMQVLEKEVEKRDSDIQQLQKQLKEAEQILATAVYQAKEKLKS 134
+K + G H LE+++ + + +QLQK+L+EA + +A+EK +
Sbjct: 1141 VKETVVISPPCTGSSEHWKPELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERH 1200
Query: 135 IEKARK 140
+ + K
Sbjct: 1201 LREELK 1206
Score = 32.7 bits (73), Expect = 0.34
Identities = 32/121 (26%), Positives = 57/121 (47%), Gaps = 10/121 (8%)
Query: 27 RERLLSALEDLEVLSRELIEMLAISRNQKLLQAGEENQV--LELLIHRDGEFQELMKLAL 84
RE L + + ++L+E+ + +N++L EN+ LE + E E ++ +
Sbjct: 2537 REDLNQVITIKDSQQKQLLEV-QLQQNKEL-----ENKYAKLEEKLKESEEANEDLRRSF 2590
Query: 85 NQGKIHHEMQVLEKEVEKRDSDIQQLQKQLKEAEQILATAVYQAKEKLKSIEKARKGAIS 144
N + E Q L KE+E I QL +Q+ ++ +Y A+ K+K E R A+
Sbjct: 2591 NA--LQEEKQDLSKEIESLKVSISQLTRQVTALQEEGTLGLYHAQLKVKEEEVHRLSALF 2648
Query: 145 S 145
S
Sbjct: 2649 S 2649
Score = 32.3 bits (72), Expect = 0.45
Identities = 27/124 (21%), Positives = 57/124 (45%), Gaps = 9/124 (7%)
Query: 42 RELIEMLAISRNQKLLQAGEENQVLELLIHRDGEFQELMKLALNQGKIHHEMQVLEKEVE 101
+E + +L+ + K Q E+N+V L E +++ + + HE +L+KE E
Sbjct: 932 KEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEE--LQHEFDLLKKENE 989
Query: 102 KRDSDIQ-------QLQKQLKEAEQILATAVYQAKEKLKSIEKARKGAISSEEIIKYAHR 154
+R +Q +L +++ E+ LA ++K+++ E R +E +Y+ +
Sbjct: 990 QRKRKLQAALINRKELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEK 1049
Query: 155 ISAS 158
S
Sbjct: 1050 CVTS 1053
Score = 32.0 bits (71), Expect = 0.58
Identities = 28/128 (21%), Positives = 65/128 (50%), Gaps = 12/128 (9%)
Query: 24 NSTRERLLSALEDLEVLSRELIEMLAISRNQKLLQAGE-ENQVLELLIHRDGEFQELMKL 82
+S+ E L ALE L +L++ + ++ K+ ++ E + + EL + Q +
Sbjct: 1566 SSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENV 1625
Query: 83 ALNQGKIHHEMQVLEKEVEK-------RDSDIQQLQKQLKEAEQILATAVYQAKEKLKSI 135
+ +I H ++ + +E ++ +++ ++ +KQL+EAEQ + + KEK++
Sbjct: 1626 SNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQ----EMEEMKEKMRKF 1681
Query: 136 EKARKGAI 143
K+++ I
Sbjct: 1682 AKSKQQKI 1689
Score = 30.0 bits (66), Expect = 2.2
Identities = 34/130 (26%), Positives = 61/130 (46%), Gaps = 22/130 (16%)
Query: 25 STRERLLSALED----LEVLSRELIEMLAISRNQKLLQAGEE----------NQVLELLI 70
ST++ L L++ + +L++++ E L SR KL + EE NQ+ EL
Sbjct: 1878 STKDGELKMLQEEVTKMNLLNQQIQEEL--SRVTKLKETAEEEKDDLEERLMNQLAELNG 1935
Query: 71 HRDGEFQELMKLALNQGKIHHEMQVLEKEVEKRDSDIQQLQKQLKEAEQILATAVYQAKE 130
Q++ + + EM+ L+K V + + + QQL K+ + E + KE
Sbjct: 1936 SIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEI------RKE 1989
Query: 131 KLKSIEKARK 140
L+ I+ A+K
Sbjct: 1990 YLEKIQGAQK 1999
Score = 29.6 bits (65), Expect = 2.9
Identities = 26/113 (23%), Positives = 61/113 (53%), Gaps = 13/113 (11%)
Query: 37 LEVLSRELIEM-LAISRNQKLLQA------GEENQVLE---LLIHRDGEFQELMKLALNQ 86
+EVL EL ++ L S L+++ +E++VLE + H + +EL + AL+Q
Sbjct: 812 IEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQ-ALSQ 870
Query: 87 GKIHHEMQVLEKEVEKRDSDIQQLQKQLKEAEQILATAVYQAKEKLKSIEKAR 139
++ E+ +++ + ++ D++ LQ+ ++E +Q + + EK+ + + +
Sbjct: 871 KEL--EITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEK 921
Score = 29.6 bits (65), Expect = 2.9
Identities = 16/54 (29%), Positives = 28/54 (51%)
Query: 87 GKIHHEMQVLEKEVEKRDSDIQQLQKQLKEAEQILATAVYQAKEKLKSIEKARK 140
G H +++V E+EV + + QK++ E E+ L +A +K+ IE K
Sbjct: 2628 GLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKLK 2681
>gi|188497714 transmembrane and coiled-coil domain family 3 [Homo
sapiens]
Length = 477
Score = 38.5 bits (88), Expect = 0.006
Identities = 36/115 (31%), Positives = 57/115 (49%), Gaps = 13/115 (11%)
Query: 39 VLSRELIEMLAISRNQKLLQAGEENQVLELLIHRDGEFQELMKLALNQGKIH--HEMQVL 96
+L +++ A S QK+L+ E+ ++ + RDG E +KL N K QV
Sbjct: 58 ILDFHKVKLTADSLKQKILKVTEQIKIEQT--SRDGNVAEYLKLVNNADKQQAGRIKQVF 115
Query: 97 EKEVEKRDSDIQQLQK-------QLKEAEQILATAVYQ--AKEKLKSIEKARKGA 142
EK+ +K I QLQK +L+E EQ A+ + +K+ LK I ++ K A
Sbjct: 116 EKKNQKSAHSIAQLQKKLEQYHRKLREIEQNGASRSSKDISKDHLKDIHRSLKDA 170
>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
Length = 2003
Score = 38.1 bits (87), Expect = 0.008
Identities = 39/144 (27%), Positives = 64/144 (44%), Gaps = 12/144 (8%)
Query: 8 EKEKERLGGGLGV-----AGGNSTRERLLSALEDLEVLSRELIEMLA----ISRNQKLLQ 58
E+E+ RL L A TR RL + ++LE++ EL + SR + +
Sbjct: 911 EEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEK 970
Query: 59 AGEENQVLELLIHRDGEFQELMKLALNQGKIHHEMQVLEKEVEKRDSDIQQLQKQLKEAE 118
+ + EL H + E KL L + +M+ E+++ + +L K+ K E
Sbjct: 971 KRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLE 1030
Query: 119 QILATAVYQA---KEKLKSIEKAR 139
LA QA +EK+KS+ K R
Sbjct: 1031 DRLAEFSSQAAEEEEKVKSLNKLR 1054
Score = 32.0 bits (71), Expect = 0.58
Identities = 38/163 (23%), Positives = 72/163 (44%), Gaps = 24/163 (14%)
Query: 2 AASSSGEKEKER----LGGGLGV--AGGNSTRERLLSALEDLEVLSRELIEMLAISR--N 53
A + SG ++ ER L G LG AG + + ++ALE + E +E R +
Sbjct: 1806 AKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILS 1865
Query: 54 QKLLQAGEENQVLELLIHRDGEFQELMKLALNQGKIHHEMQVLEKEVEKRDSDIQQLQKQ 113
KL++ E+ L ++ L + L ++EK + ++QL++Q
Sbjct: 1866 GKLVRRAEKR---------------LKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQ 1910
Query: 114 LKEAEQILATAVYQAKEKLKSIEKARKGAIS-SEEIIKYAHRI 155
L+EAE+ + A + + +E + A S + E+ +R+
Sbjct: 1911 LEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRL 1953
Score = 31.6 bits (70), Expect = 0.76
Identities = 32/125 (25%), Positives = 59/125 (47%), Gaps = 10/125 (8%)
Query: 23 GNSTRERLLSALEDLEVLSRELIEM--LAISRNQKLLQAGEENQVLELLIHRDGEFQELM 80
G R +L L D EV E + LA++ +KL E ++ EL Q
Sbjct: 1612 GEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKL-----EGELEELKAQMASAGQGKE 1666
Query: 81 KLALNQGKIHHEMQVLEKEVEKRDSDIQQLQKQLKEAEQI---LATAVYQAKEKLKSIEK 137
+ K+ +M+ L +EVE+ + +++ Q +E+E+ L V + +E+L + ++
Sbjct: 1667 EAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDR 1726
Query: 138 ARKGA 142
AR+ A
Sbjct: 1727 ARRQA 1731
Score = 30.0 bits (66), Expect = 2.2
Identities = 35/139 (25%), Positives = 58/139 (41%), Gaps = 13/139 (9%)
Query: 4 SSSGEKEKERLGGGLGVAGGNSTRERLLSALEDLEVLSRELIEMLAISRNQKLLQAGEEN 63
SS +E+E+ V N R + + + D+E R+ + K GE +
Sbjct: 1037 SSQAAEEEEK------VKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESS 1090
Query: 64 QVLELLIHRDGEFQELMKLALNQGKIHHEMQVLEKEVEKRDSDIQQLQKQLKEAEQILAT 123
++ E ++ + +EL G+ E+Q E QL K L+EA+ LA
Sbjct: 1091 ELQEQMVEQQQRAEELRA---QLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALA- 1146
Query: 124 AVYQAKEKLKSIEKARKGA 142
+A+E L+S AR A
Sbjct: 1147 ---EAQEDLESERVARTKA 1162
Score = 28.5 bits (62), Expect = 6.5
Identities = 30/141 (21%), Positives = 57/141 (40%), Gaps = 8/141 (5%)
Query: 7 GEKEKERLGGGLGVAGGNSTRERLLSALEDLEVLSRELIEMLAISRNQKLLQAGEENQVL 66
G KE+E R +LL +L + + E E L R + + +
Sbjct: 1111 GRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLG 1170
Query: 67 ELLIHRDGEFQELMKLALNQGKIHHEMQ--------VLEKEVEKRDSDIQQLQKQLKEAE 118
E L GE ++ + Q ++ + + LE+E ++ +Q+L+++ +A
Sbjct: 1171 EELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQAL 1230
Query: 119 QILATAVYQAKEKLKSIEKAR 139
LA + QA+ + EK R
Sbjct: 1231 GELAEQLEQARRGKGAWEKTR 1251
>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
Length = 1995
Score = 38.1 bits (87), Expect = 0.008
Identities = 39/144 (27%), Positives = 64/144 (44%), Gaps = 12/144 (8%)
Query: 8 EKEKERLGGGLGV-----AGGNSTRERLLSALEDLEVLSRELIEMLA----ISRNQKLLQ 58
E+E+ RL L A TR RL + ++LE++ EL + SR + +
Sbjct: 903 EEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEK 962
Query: 59 AGEENQVLELLIHRDGEFQELMKLALNQGKIHHEMQVLEKEVEKRDSDIQQLQKQLKEAE 118
+ + EL H + E KL L + +M+ E+++ + +L K+ K E
Sbjct: 963 KRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLE 1022
Query: 119 QILATAVYQA---KEKLKSIEKAR 139
LA QA +EK+KS+ K R
Sbjct: 1023 DRLAEFSSQAAEEEEKVKSLNKLR 1046
Score = 32.0 bits (71), Expect = 0.58
Identities = 38/163 (23%), Positives = 72/163 (44%), Gaps = 24/163 (14%)
Query: 2 AASSSGEKEKER----LGGGLGV--AGGNSTRERLLSALEDLEVLSRELIEMLAISR--N 53
A + SG ++ ER L G LG AG + + ++ALE + E +E R +
Sbjct: 1798 AKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILS 1857
Query: 54 QKLLQAGEENQVLELLIHRDGEFQELMKLALNQGKIHHEMQVLEKEVEKRDSDIQQLQKQ 113
KL++ E+ L ++ L + L ++EK + ++QL++Q
Sbjct: 1858 GKLVRRAEKR---------------LKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQ 1902
Query: 114 LKEAEQILATAVYQAKEKLKSIEKARKGAIS-SEEIIKYAHRI 155
L+EAE+ + A + + +E + A S + E+ +R+
Sbjct: 1903 LEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRL 1945
Score = 31.6 bits (70), Expect = 0.76
Identities = 32/125 (25%), Positives = 59/125 (47%), Gaps = 10/125 (8%)
Query: 23 GNSTRERLLSALEDLEVLSRELIEM--LAISRNQKLLQAGEENQVLELLIHRDGEFQELM 80
G R +L L D EV E + LA++ +KL E ++ EL Q
Sbjct: 1604 GEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKL-----EGELEELKAQMASAGQGKE 1658
Query: 81 KLALNQGKIHHEMQVLEKEVEKRDSDIQQLQKQLKEAEQI---LATAVYQAKEKLKSIEK 137
+ K+ +M+ L +EVE+ + +++ Q +E+E+ L V + +E+L + ++
Sbjct: 1659 EAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDR 1718
Query: 138 ARKGA 142
AR+ A
Sbjct: 1719 ARRQA 1723
Score = 30.0 bits (66), Expect = 2.2
Identities = 35/139 (25%), Positives = 58/139 (41%), Gaps = 13/139 (9%)
Query: 4 SSSGEKEKERLGGGLGVAGGNSTRERLLSALEDLEVLSRELIEMLAISRNQKLLQAGEEN 63
SS +E+E+ V N R + + + D+E R+ + K GE +
Sbjct: 1029 SSQAAEEEEK------VKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESS 1082
Query: 64 QVLELLIHRDGEFQELMKLALNQGKIHHEMQVLEKEVEKRDSDIQQLQKQLKEAEQILAT 123
++ E ++ + +EL G+ E+Q E QL K L+EA+ LA
Sbjct: 1083 ELQEQMVEQQQRAEELRA---QLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALA- 1138
Query: 124 AVYQAKEKLKSIEKARKGA 142
+A+E L+S AR A
Sbjct: 1139 ---EAQEDLESERVARTKA 1154
Score = 28.5 bits (62), Expect = 6.5
Identities = 30/141 (21%), Positives = 57/141 (40%), Gaps = 8/141 (5%)
Query: 7 GEKEKERLGGGLGVAGGNSTRERLLSALEDLEVLSRELIEMLAISRNQKLLQAGEENQVL 66
G KE+E R +LL +L + + E E L R + + +
Sbjct: 1103 GRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLG 1162
Query: 67 ELLIHRDGEFQELMKLALNQGKIHHEMQ--------VLEKEVEKRDSDIQQLQKQLKEAE 118
E L GE ++ + Q ++ + + LE+E ++ +Q+L+++ +A
Sbjct: 1163 EELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQAL 1222
Query: 119 QILATAVYQAKEKLKSIEKAR 139
LA + QA+ + EK R
Sbjct: 1223 GELAEQLEQARRGKGAWEKTR 1243
>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
Length = 2036
Score = 38.1 bits (87), Expect = 0.008
Identities = 39/144 (27%), Positives = 64/144 (44%), Gaps = 12/144 (8%)
Query: 8 EKEKERLGGGLGV-----AGGNSTRERLLSALEDLEVLSRELIEMLA----ISRNQKLLQ 58
E+E+ RL L A TR RL + ++LE++ EL + SR + +
Sbjct: 944 EEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEK 1003
Query: 59 AGEENQVLELLIHRDGEFQELMKLALNQGKIHHEMQVLEKEVEKRDSDIQQLQKQLKEAE 118
+ + EL H + E KL L + +M+ E+++ + +L K+ K E
Sbjct: 1004 KRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLE 1063
Query: 119 QILATAVYQA---KEKLKSIEKAR 139
LA QA +EK+KS+ K R
Sbjct: 1064 DRLAEFSSQAAEEEEKVKSLNKLR 1087
Score = 32.0 bits (71), Expect = 0.58
Identities = 38/163 (23%), Positives = 72/163 (44%), Gaps = 24/163 (14%)
Query: 2 AASSSGEKEKER----LGGGLGV--AGGNSTRERLLSALEDLEVLSRELIEMLAISR--N 53
A + SG ++ ER L G LG AG + + ++ALE + E +E R +
Sbjct: 1839 AKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILS 1898
Query: 54 QKLLQAGEENQVLELLIHRDGEFQELMKLALNQGKIHHEMQVLEKEVEKRDSDIQQLQKQ 113
KL++ E+ L ++ L + L ++EK + ++QL++Q
Sbjct: 1899 GKLVRRAEKR---------------LKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQ 1943
Query: 114 LKEAEQILATAVYQAKEKLKSIEKARKGAIS-SEEIIKYAHRI 155
L+EAE+ + A + + +E + A S + E+ +R+
Sbjct: 1944 LEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRL 1986
Score = 31.6 bits (70), Expect = 0.76
Identities = 32/125 (25%), Positives = 59/125 (47%), Gaps = 10/125 (8%)
Query: 23 GNSTRERLLSALEDLEVLSRELIEM--LAISRNQKLLQAGEENQVLELLIHRDGEFQELM 80
G R +L L D EV E + LA++ +KL E ++ EL Q
Sbjct: 1645 GEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKL-----EGELEELKAQMASAGQGKE 1699
Query: 81 KLALNQGKIHHEMQVLEKEVEKRDSDIQQLQKQLKEAEQI---LATAVYQAKEKLKSIEK 137
+ K+ +M+ L +EVE+ + +++ Q +E+E+ L V + +E+L + ++
Sbjct: 1700 EAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDR 1759
Query: 138 ARKGA 142
AR+ A
Sbjct: 1760 ARRQA 1764
Score = 30.0 bits (66), Expect = 2.2
Identities = 35/139 (25%), Positives = 58/139 (41%), Gaps = 13/139 (9%)
Query: 4 SSSGEKEKERLGGGLGVAGGNSTRERLLSALEDLEVLSRELIEMLAISRNQKLLQAGEEN 63
SS +E+E+ V N R + + + D+E R+ + K GE +
Sbjct: 1070 SSQAAEEEEK------VKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESS 1123
Query: 64 QVLELLIHRDGEFQELMKLALNQGKIHHEMQVLEKEVEKRDSDIQQLQKQLKEAEQILAT 123
++ E ++ + +EL G+ E+Q E QL K L+EA+ LA
Sbjct: 1124 ELQEQMVEQQQRAEELRA---QLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALA- 1179
Query: 124 AVYQAKEKLKSIEKARKGA 142
+A+E L+S AR A
Sbjct: 1180 ---EAQEDLESERVARTKA 1195
Score = 28.5 bits (62), Expect = 6.5
Identities = 30/141 (21%), Positives = 57/141 (40%), Gaps = 8/141 (5%)
Query: 7 GEKEKERLGGGLGVAGGNSTRERLLSALEDLEVLSRELIEMLAISRNQKLLQAGEENQVL 66
G KE+E R +LL +L + + E E L R + + +
Sbjct: 1144 GRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLG 1203
Query: 67 ELLIHRDGEFQELMKLALNQGKIHHEMQ--------VLEKEVEKRDSDIQQLQKQLKEAE 118
E L GE ++ + Q ++ + + LE+E ++ +Q+L+++ +A
Sbjct: 1204 EELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQAL 1263
Query: 119 QILATAVYQAKEKLKSIEKAR 139
LA + QA+ + EK R
Sbjct: 1264 GELAEQLEQARRGKGAWEKTR 1284
>gi|8923243 palmdelphin [Homo sapiens]
Length = 551
Score = 37.7 bits (86), Expect = 0.011
Identities = 26/75 (34%), Positives = 43/75 (57%), Gaps = 6/75 (8%)
Query: 74 GEFQELMKLALNQGKIHHEMQVLEKEVEKRDSDIQQLQKQLKEAEQILATAVYQAKEKLK 133
G+ QE MK Q + H++QVLE+ + + + +IQ L+K AE ++T +KLK
Sbjct: 58 GKEQEEMKKQNQQDQ--HQIQVLEQSILRLEKEIQDLEK----AELQISTKEEAILKKLK 111
Query: 134 SIEKARKGAISSEEI 148
SIE+ + I S ++
Sbjct: 112 SIERTTEDIIRSVKV 126
>gi|32698866 spindle pole body component 24 homolog [Homo sapiens]
Length = 197
Score = 37.7 bits (86), Expect = 0.011
Identities = 29/137 (21%), Positives = 68/137 (49%), Gaps = 6/137 (4%)
Query: 31 LSALEDLEVLSRELIEMLAISR---NQKLLQAGEENQVLELLIHRDGEFQELMKLALNQG 87
++A D+E +S+ L+ +L +R Q+ L E V LL +DG ++L ++ +
Sbjct: 1 MAAFRDIEEVSQGLLSLLGANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEK 60
Query: 88 KIHHEMQVLEKEVEKRDSDIQQLQKQLKEA---EQILATAVYQAKEKLKSIEKARKGAIS 144
++ + +++V + ++QQL+ L+EA + L ++ Q +L+ +++
Sbjct: 61 EVAQSLLNAKEQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLER 120
Query: 145 SEEIIKYAHRISASNAV 161
E+ + ++ +AV
Sbjct: 121 QEKEVDEDTTVTIPSAV 137
>gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens]
Length = 1233
Score = 37.4 bits (85), Expect = 0.014
Identities = 18/63 (28%), Positives = 38/63 (60%)
Query: 78 ELMKLALNQGKIHHEMQVLEKEVEKRDSDIQQLQKQLKEAEQILATAVYQAKEKLKSIEK 137
EL + GK+ E Q +EKE++++DS++ Q + Q +A++ + + + + KS++
Sbjct: 262 ELKEKKKELGKMMREQQQIEKEIKEKDSELNQKRPQYIKAKENTSHKIKKLEAAKKSLQN 321
Query: 138 ARK 140
A+K
Sbjct: 322 AQK 324
Score = 31.6 bits (70), Expect = 0.76
Identities = 22/81 (27%), Positives = 43/81 (53%), Gaps = 7/81 (8%)
Query: 77 QELMKLALNQGKIHHEMQVLEKEVEKRDSDIQQLQKQLKEAEQIL---ATAVYQAKE--- 130
+E+ K K+ E++ +KE+ K + QQ++K++KE + L +AKE
Sbjct: 247 KEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSELNQKRPQYIKAKENTS 306
Query: 131 -KLKSIEKARKGAISSEEIIK 150
K+K +E A+K ++++ K
Sbjct: 307 HKIKKLEAAKKSLQNAQKHYK 327
>gi|38044112 restin isoform b [Homo sapiens]
Length = 1392
Score = 37.0 bits (84), Expect = 0.018
Identities = 39/155 (25%), Positives = 76/155 (49%), Gaps = 20/155 (12%)
Query: 5 SSGEKEKERLGGGLGVAGGNSTRERLLSALEDLEVLSRELIEMLAISRNQKLLQ-AGEEN 63
S+ ++E +L LG + T + L E+ VL+ +L+EM R K ++ A EE
Sbjct: 1127 SALQEENVKLAEELGRSRDEVTSHQKLE--EERSVLNNQLLEMK--KRESKFIKDADEEK 1182
Query: 64 QVLE--------LLIHRDGEFQELM-KLALNQGK------IHHEMQVLEKEVEKRDSDIQ 108
L+ LL +D E ++L ++ + +G+ +H +Q LE + K + ++
Sbjct: 1183 ASLQKSISITSALLTEKDAELEKLRNEVTVLRGENASAKSLHSVVQTLESDKVKLELKVK 1242
Query: 109 QLQKQLKEAEQILATAVYQAKEKLKSIEKARKGAI 143
L+ QLKE ++ L+++ + E+A++ I
Sbjct: 1243 NLELQLKENKRQLSSSSGNTDTQADEDERAQESQI 1277
Score = 30.4 bits (67), Expect = 1.7
Identities = 26/124 (20%), Positives = 58/124 (46%), Gaps = 17/124 (13%)
Query: 24 NSTRERLLSALEDLEVLSRELIEMLAISRNQKLLQAGEENQVLELLIHRDGEFQELMKLA 83
+S E+L L D+E RE E R ++L++A E+ + + E+MK++
Sbjct: 846 SSDLEKLRENLADMEAKFREKDE-----REEQLIKAKEK---------LENDIAEIMKMS 891
Query: 84 LNQGKIHHEMQVLEKEVEKRDSDIQQLQKQLKEAEQILATAVYQAKEKLKSIEKARKGAI 143
G ++ + E+ ++ D+++LQ +L +A + + ++ E++++ A
Sbjct: 892 ---GDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAA 948
Query: 144 SSEE 147
E
Sbjct: 949 KKHE 952
Score = 29.6 bits (65), Expect = 2.9
Identities = 23/93 (24%), Positives = 48/93 (51%), Gaps = 6/93 (6%)
Query: 50 ISRNQKLLQAGEENQ--VLELLIHRDGEFQELMKLALNQGKIHHEMQVL----EKEVEKR 103
IS L +A +E Q + +LL RD E E+ K + G+I E+ + ++ V +
Sbjct: 347 ISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHDQHVLEL 406
Query: 104 DSDIQQLQKQLKEAEQILATAVYQAKEKLKSIE 136
++ + QL+ ++ A++ + Q +E+ + +E
Sbjct: 407 EAKMDQLRTMVEAADREKVELLNQLEEEKRKVE 439
>gi|4506751 restin isoform a [Homo sapiens]
Length = 1427
Score = 37.0 bits (84), Expect = 0.018
Identities = 39/155 (25%), Positives = 76/155 (49%), Gaps = 20/155 (12%)
Query: 5 SSGEKEKERLGGGLGVAGGNSTRERLLSALEDLEVLSRELIEMLAISRNQKLLQ-AGEEN 63
S+ ++E +L LG + T + L E+ VL+ +L+EM R K ++ A EE
Sbjct: 1162 SALQEENVKLAEELGRSRDEVTSHQKLE--EERSVLNNQLLEMK--KRESKFIKDADEEK 1217
Query: 64 QVLE--------LLIHRDGEFQELM-KLALNQGK------IHHEMQVLEKEVEKRDSDIQ 108
L+ LL +D E ++L ++ + +G+ +H +Q LE + K + ++
Sbjct: 1218 ASLQKSISITSALLTEKDAELEKLRNEVTVLRGENASAKSLHSVVQTLESDKVKLELKVK 1277
Query: 109 QLQKQLKEAEQILATAVYQAKEKLKSIEKARKGAI 143
L+ QLKE ++ L+++ + E+A++ I
Sbjct: 1278 NLELQLKENKRQLSSSSGNTDTQADEDERAQESQI 1312
Score = 30.4 bits (67), Expect = 1.7
Identities = 26/124 (20%), Positives = 58/124 (46%), Gaps = 17/124 (13%)
Query: 24 NSTRERLLSALEDLEVLSRELIEMLAISRNQKLLQAGEENQVLELLIHRDGEFQELMKLA 83
+S E+L L D+E RE E R ++L++A E+ + + E+MK++
Sbjct: 881 SSDLEKLRENLADMEAKFREKDE-----REEQLIKAKEK---------LENDIAEIMKMS 926
Query: 84 LNQGKIHHEMQVLEKEVEKRDSDIQQLQKQLKEAEQILATAVYQAKEKLKSIEKARKGAI 143
G ++ + E+ ++ D+++LQ +L +A + + ++ E++++ A
Sbjct: 927 ---GDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAA 983
Query: 144 SSEE 147
E
Sbjct: 984 KKHE 987
Score = 29.6 bits (65), Expect = 2.9
Identities = 23/93 (24%), Positives = 48/93 (51%), Gaps = 6/93 (6%)
Query: 50 ISRNQKLLQAGEENQ--VLELLIHRDGEFQELMKLALNQGKIHHEMQVL----EKEVEKR 103
IS L +A +E Q + +LL RD E E+ K + G+I E+ + ++ V +
Sbjct: 347 ISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHDQHVLEL 406
Query: 104 DSDIQQLQKQLKEAEQILATAVYQAKEKLKSIE 136
++ + QL+ ++ A++ + Q +E+ + +E
Sbjct: 407 EAKMDQLRTMVEAADREKVELLNQLEEEKRKVE 439
>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
Length = 2325
Score = 37.0 bits (84), Expect = 0.018
Identities = 24/95 (25%), Positives = 47/95 (49%), Gaps = 6/95 (6%)
Query: 73 DGEFQELM-KLALNQGKIHHE-----MQVLEKEVEKRDSDIQQLQKQLKEAEQILATAVY 126
DG + LM +L + + HHE ++ +EK + KR S++++ + L EAE L+
Sbjct: 1395 DGNVESLMTELEIEKSLKHHEDIVDEIECIEKTLLKRRSELREADRLLAEAESELSCTKE 1454
Query: 127 QAKEKLKSIEKARKGAISSEEIIKYAHRISASNAV 161
+ K ++ A++ + +E + R + AV
Sbjct: 1455 KTKNAVEKFTDAKRSLLQTESDAEELERRAQETAV 1489
Score = 36.6 bits (83), Expect = 0.024
Identities = 24/87 (27%), Positives = 45/87 (51%), Gaps = 12/87 (13%)
Query: 50 ISRNQKLLQAGEENQVLELLIHRDGEFQELMKLALNQGKIHHEMQVLEKEVEKRDSDIQQ 109
+++ +++L A EEN +E L KL LN K+ E+ L ++ +DI
Sbjct: 1803 LAQTKRVLAAAEENSKMEQ--------SNLEKLELNVRKLQQELDQLNRDKLSLHNDISA 1854
Query: 110 LQKQLKEAEQILATAVYQAKEKLKSIE 136
+Q+QL+E + AV +E+L +++
Sbjct: 1855 MQQQLQEKRE----AVNSLQEELANVQ 1877
Score = 33.1 bits (74), Expect = 0.26
Identities = 29/109 (26%), Positives = 53/109 (48%), Gaps = 8/109 (7%)
Query: 26 TRERLLSALEDLEVLSRELIEMLAISRNQKLLQAGEENQVLELLIHRDGEFQELMKLALN 85
T L+ A + L L + ++ K+ Q ++ +++ +D +FQ L K
Sbjct: 1487 TAVNLVKADQQLRSLQADAKDL----EQHKIKQEEILKEINKIVAAKDSDFQCLSK---K 1539
Query: 86 QGKIHHEMQVLEKEVEKRDSDIQQLQKQLKEAEQILATAVYQAKEKLKS 134
+ K+ E+Q L+K++E + + + LKE+E +L A EKLKS
Sbjct: 1540 KEKLTEELQKLQKDIEMAERNEDHHLQVLKESE-VLLQAKRAELEKLKS 1587
Score = 32.0 bits (71), Expect = 0.58
Identities = 27/121 (22%), Positives = 60/121 (49%), Gaps = 14/121 (11%)
Query: 24 NSTRERLLSALEDLEVLSRELIEMLAISRNQKLLQAGEENQVLELLIHRDGEFQELMKLA 83
NS +E L + + L + ++L+ +++Q +L + E+ ++ + + F++ K
Sbjct: 1867 NSLQEELANVQDHLNLAKQDLLHT---TKHQDVLLS-EQTRLQKDISEWANRFEDCQK-- 1920
Query: 84 LNQGKIHHEMQVLEKEVEK-------RDSDIQQLQKQLKEAEQILATAVYQAKEKLKSIE 136
+ ++QVL+ E+E+ ++ Q+LQK+ + E L T+ KE+ +E
Sbjct: 1921 -EEETKQQQLQVLQNEIEENKLKLVQQEMMFQRLQKERESEESKLETSKVTLKEQQHQLE 1979
Query: 137 K 137
K
Sbjct: 1980 K 1980
Score = 28.9 bits (63), Expect = 4.9
Identities = 26/95 (27%), Positives = 47/95 (49%), Gaps = 10/95 (10%)
Query: 54 QKLLQAGEENQVLELLIH--------RDGEFQELMKLALNQGKIHHEMQVLEKEVEKRDS 105
Q++L+A EE + LE I +D +++L K+ E LE ++EK+
Sbjct: 465 QQILRATEEFKQLEEAIQLKKISEAGKDLLYKQLSGRLQLVNKLRQEALDLELQMEKQKQ 524
Query: 106 DIQQLQKQLKEAEQILATAVYQAKEKLKSIEKARK 140
+I QK++K+ + +A +K+ S KA+K
Sbjct: 525 EIAGKQKEIKDLQ--IAIDSLDSKDPKHSHMKAQK 557
Score = 28.9 bits (63), Expect = 4.9
Identities = 24/121 (19%), Positives = 53/121 (43%), Gaps = 7/121 (5%)
Query: 27 RERLLSALEDLEVLSRELIEMLAISRNQKLLQAGEENQVLELLIHRDGEFQELMKLALNQ 86
+E LL L ++E R+ +E++A+ + E L+ + Q+ Q
Sbjct: 646 KETLLQRLTEVEQ-ERDQLEIVAMDAENMRKELAELESALQEQHEVNASLQQ------TQ 698
Query: 87 GKIHHEMQVLEKEVEKRDSDIQQLQKQLKEAEQILATAVYQAKEKLKSIEKARKGAISSE 146
G + LE + RD++ QL+++L++ ++ + +L+ +A K A+
Sbjct: 699 GDLSAYEAELEARLNLRDAEANQLKEELEKVTRLTQLEQSALQAELEKERQALKNALGKA 758
Query: 147 E 147
+
Sbjct: 759 Q 759
Score = 28.9 bits (63), Expect = 4.9
Identities = 27/108 (25%), Positives = 50/108 (46%), Gaps = 5/108 (4%)
Query: 35 EDLEVLSRELIEMLAISRNQKLLQAGEENQVLELLIHRDGEF---QELMKLALNQGKIHH 91
++ +V R+L E +A+ + + E Q E + F Q ++ + +IH+
Sbjct: 859 DEAQVRERKLQEEMALQQEKLATGQEEFRQACERALEARMNFDKRQHEARIQQMENEIHY 918
Query: 92 EMQVLEKEVEKRDSDIQQLQKQLKEAEQILATAVYQAKEKLKSIEKAR 139
+ L+ E + QLQ+ +E E+ILA + EK K +E A+
Sbjct: 919 LQENLKSMEEIQGLTDLQLQEADEEKERILAQ--LRELEKKKKLEDAK 964
Score = 28.9 bits (63), Expect = 4.9
Identities = 37/155 (23%), Positives = 75/155 (48%), Gaps = 31/155 (20%)
Query: 8 EKEKERLGGGLGVAGGNSTRERLLSALEDLEVLSRELIEMLAISRNQKLLQAGEENQVLE 67
EKE+E L L + T L + L+ L++ + EL + L + +Q++ + E+ QV
Sbjct: 1678 EKEEENLQVVLRQMSKHKTE--LKNILDMLQLENHEL-QGLKLQHDQRVSEL-EKTQVA- 1732
Query: 68 LLIHRDGEFQELMKLALNQ-GKIHHEMQVLEK---EVEKRDSDIQQLQ------------ 111
++ E + L +++ Q G+I + Q+LE+ E+E+ ++ + LQ
Sbjct: 1733 -VLEEKLELENLQQISQQQKGEIEWQKQLLERDKREIERMTAESRALQSCVECLSKEKED 1791
Query: 112 ---------KQLKEAEQILATAVYQAKEKLKSIEK 137
K+L + +++LA A +K + ++EK
Sbjct: 1792 LQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEK 1826
>gi|157738667 FYVE and coiled-coil domain containing 1 [Homo
sapiens]
Length = 1478
Score = 36.6 bits (83), Expect = 0.024
Identities = 37/136 (27%), Positives = 65/136 (47%), Gaps = 19/136 (13%)
Query: 27 RERLLSALEDLEVLSRELIEMLAISRNQKLLQAGEENQVLELLIHRDGEFQELMKLALNQ 86
R R L ALE +LIE+L + Q+ + +N+ EL +L ++Q
Sbjct: 726 RHRELRALESQCQQQTQLIEVLTAEKGQQGVGPPTDNEARELAAQL---ALSQAQLEVHQ 782
Query: 87 GKIHH-EMQVLEKEVEKRDS--DIQQLQKQLKEAEQIL---ATAVYQAKEKLKSIEKA-- 138
G++ + QV++ + + R + D ++Q QL AE +L T V Q KE+ +++ +A
Sbjct: 783 GEVQRLQAQVVDLQAKMRAALDDQDKVQSQLSMAEAVLREHKTLVQQLKEQNEALNRAHV 842
Query: 139 --------RKGAISSE 146
R+GA+ E
Sbjct: 843 QELLQCSEREGALQEE 858
Score = 33.9 bits (76), Expect = 0.15
Identities = 28/108 (25%), Positives = 49/108 (45%), Gaps = 6/108 (5%)
Query: 31 LSALEDLEVLSRELIEMLAISRNQKLLQAGEENQVL-----ELLIHRDGEFQELMKLALN 85
L ED L++ +A ++L G+E L ELL H +EL +L
Sbjct: 435 LQLKEDARASLERLVKEMA-PLQEELSGKGQEADQLWRRLQELLAHTSSWEEELAELRRE 493
Query: 86 QGKIHHEMQVLEKEVEKRDSDIQQLQKQLKEAEQILATAVYQAKEKLK 133
+ + E ++LE+EV +Q L+ QL + Q ++ Q K+ ++
Sbjct: 494 KKQQQEEKELLEQEVRSLTRQLQFLETQLAQVSQHVSDLEEQKKQLIQ 541
>gi|81295809 pericentrin [Homo sapiens]
Length = 3336
Score = 36.6 bits (83), Expect = 0.024
Identities = 35/119 (29%), Positives = 51/119 (42%), Gaps = 13/119 (10%)
Query: 4 SSSGEKEKERLGGGLGVAGGNSTRERLLSALEDLEVLSRELIEMLAISRNQKLLQAGEEN 63
S +G + E L G G + + L +ALE E LSR L + Q +
Sbjct: 1766 SQAGSLQSELLCSQAGGPRGQALQGELEAALEAKEALSRLLAD-----------QERRHS 1814
Query: 64 QVLELLIHRDGEFQELMKLALNQGKIHHEMQVLEKEVEKRDSDIQQLQKQLKEAEQILA 122
Q LE L R +E +L L ++ + + E EVE S IQ+ + LK E +A
Sbjct: 1815 QALEALQQRLQGAEEAAELQL--AELERNVALREAEVEDMASRIQEFEAALKAKEATIA 1871
Score = 29.3 bits (64), Expect = 3.8
Identities = 29/130 (22%), Positives = 59/130 (45%), Gaps = 16/130 (12%)
Query: 27 RERLLSALEDLEVLSRELIEMLAISRNQKLLQAGEENQVLELLIHRDGEFQE--LMKLAL 84
R +L +DL +E+ R+++LL + E +H+D + L KL
Sbjct: 2737 RSQLSELQKDLAAEKSRTLELSEALRHERLLTEQLSQRTQEACVHQDTQAHHALLQKLKE 2796
Query: 85 NQGKIHHEMQVLEKEVEKRDSDIQQLQKQ-------LKEAEQILAT------AVYQAKEK 131
+ ++ +LEK ++ QQL+ + L+ +++ AT A++ K +
Sbjct: 2797 EKSRVVDLQAMLEKVQQQALHSQQQLEAEAQKHCEALRREKEVSATLKSTVEALHTQKRE 2856
Query: 132 LK-SIEKARK 140
L+ S+E+ R+
Sbjct: 2857 LRCSLERERE 2866
>gi|239787821 syncoilin, intermediate filament 1 isoform 2 [Homo
sapiens]
Length = 476
Score = 35.8 bits (81), Expect = 0.040
Identities = 36/154 (23%), Positives = 66/154 (42%), Gaps = 25/154 (16%)
Query: 34 LEDLEVLSRELIEMLAISRNQKLLQAGEENQVLELLIHRDGEFQELMKLALNQGKIHHEM 93
L++ LS + ++A SR L+ E Q L LL ++ + L + ++ +
Sbjct: 318 LQESRRLSAQFENLMAESRQD--LEEEYEPQFLRLLERKEAGTKALQRTQAEIQEMKEAL 375
Query: 94 QVLEKEV------------------EKRDSDIQQLQKQLKEAEQ---ILATAVYQAKEKL 132
+ L+ E +KRD ++QQ ++QL+E E+ L V ++K
Sbjct: 376 RPLQAEARQLRLQNRNLEDQIALVRQKRDEEVQQYREQLEEMEERQRQLRNGVQLQQQKN 435
Query: 133 KSIEKARKGAISSEEIIKYAHRISASNAVCAPLT 166
K +E+ R +EE+ Y + +C P T
Sbjct: 436 KEMEQLRLSL--AEELSTYKGCLEIYGQICNPET 467
>gi|63252904 tropomyosin 1 alpha chain isoform 6 [Homo sapiens]
Length = 245
Score = 35.8 bits (81), Expect = 0.040
Identities = 45/166 (27%), Positives = 67/166 (40%), Gaps = 10/166 (6%)
Query: 1 MAASSSGEKEKERLGGGLGVAGGNSTRERLLSALEDLEVLSRELIEMLAISRNQKLLQAG 60
MA SSS E + ++ A R L D E RE E S N+++
Sbjct: 1 MAGSSSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVE 60
Query: 61 EE-NQVLELLIHRDGEFQELMKLALNQGKIHHEMQVLEKEVEKRDSDIQQLQKQLKEAEQ 119
EE ++ E L + +E K A + M+V+E +K + ++ + QLKEA+
Sbjct: 61 EELDRAQERLATALQKLEEAEKAA---DESERGMKVIESRAQKDEEKMEIQEIQLKEAKH 117
Query: 120 ILATAVYQAKEKLKSIEKARKGAISSEEIIKYAHRISASNAVCAPL 165
I A K E ARK I ++ + R S CA L
Sbjct: 118 IAEDA------DRKYEEVARKLVIIESDLERAEERAELSEGKCAEL 157
>gi|39930479 DIX domain containing 1 isoform b [Homo sapiens]
Length = 472
Score = 35.8 bits (81), Expect = 0.040
Identities = 26/134 (19%), Positives = 71/134 (52%), Gaps = 18/134 (13%)
Query: 27 RERLLSALEDLEVLSRELIEMLAISRN---------QKLLQAGEENQVLELLIHRDGEFQ 77
+ RL ++E+ + L +EL++ +RN Q+L Q ++ VL+L Q
Sbjct: 129 QSRLDQSMEENQDLKKELLKCKQEARNLQGIKDALQQRLTQ--QDTSVLQLK-------Q 179
Query: 78 ELMKLALNQGKIHHEMQVLEKEVEKRDSDIQQLQKQLKEAEQILATAVYQAKEKLKSIEK 137
EL++ +++ ++H++ L++++++R+ + + +K+L + +++L + +E L+ +
Sbjct: 180 ELLRANMDKDELHNQNVDLQRKLDERNRLLGEYKKELGQKDRLLQQHQAKLEEALRKLSD 239
Query: 138 ARKGAISSEEIIKY 151
+ E +++
Sbjct: 240 VSYHQVDLERELEH 253
>gi|83816971 DIX domain containing 1 isoform a [Homo sapiens]
Length = 683
Score = 35.8 bits (81), Expect = 0.040
Identities = 26/134 (19%), Positives = 71/134 (52%), Gaps = 18/134 (13%)
Query: 27 RERLLSALEDLEVLSRELIEMLAISRN---------QKLLQAGEENQVLELLIHRDGEFQ 77
+ RL ++E+ + L +EL++ +RN Q+L Q ++ VL+L Q
Sbjct: 340 QSRLDQSMEENQDLKKELLKCKQEARNLQGIKDALQQRLTQ--QDTSVLQLK-------Q 390
Query: 78 ELMKLALNQGKIHHEMQVLEKEVEKRDSDIQQLQKQLKEAEQILATAVYQAKEKLKSIEK 137
EL++ +++ ++H++ L++++++R+ + + +K+L + +++L + +E L+ +
Sbjct: 391 ELLRANMDKDELHNQNVDLQRKLDERNRLLGEYKKELGQKDRLLQQHQAKLEEALRKLSD 450
Query: 138 ARKGAISSEEIIKY 151
+ E +++
Sbjct: 451 VSYHQVDLERELEH 464
>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
Length = 1946
Score = 35.8 bits (81), Expect = 0.040
Identities = 29/132 (21%), Positives = 57/132 (43%), Gaps = 7/132 (5%)
Query: 22 GGNSTRERLLSALEDLEVLSRELIEMLAISRNQKLLQAGEENQVLELLIHRDGEFQELMK 81
G + E LL A E + + + +L+ + + A + + E++ ++ K
Sbjct: 1710 GRRLSEEELLEATERINLFYTQNTSLLSQKKKLEADVARMQKEAEEVVQECQNAEEKAKK 1769
Query: 82 LALNQGKIHHEMQV-------LEKEVEKRDSDIQQLQKQLKEAEQILATAVYQAKEKLKS 134
A+ + E++ LE+ E + I LQK+L EAEQ+ + +KL+S
Sbjct: 1770 AAIEAANLSEELKKKQDTIAHLERTRENMEQTITDLQKRLAEAEQMALMGSRKQIQKLES 1829
Query: 135 IEKARKGAISSE 146
+ +G + E
Sbjct: 1830 RVRELEGELEGE 1841
Score = 28.9 bits (63), Expect = 4.9
Identities = 43/147 (29%), Positives = 66/147 (44%), Gaps = 21/147 (14%)
Query: 4 SSSGE-----KEKERLGGGLGVAGGNSTRERLLSALEDLE-VLSRELIEMLAISRNQKLL 57
S SGE +EKE L L N TR+ +EDL L +E A++ L
Sbjct: 1294 SESGEFLRRLEEKEALINQLSREKSNFTRQ-----IEDLRGQLEKETKSQSALAH---AL 1345
Query: 58 QAGEENQVLELLIHRDGEFQELM-KLALNQGKIHHEM----QVLEKEVEKRDSDIQQLQK 112
Q + + +LL + E QE+ +L K++ EM E V +R D++ +K
Sbjct: 1346 QKAQRD--CDLLREQYEEEQEVKAELHRTLSKVNAEMVQWRMKYENNVIQRTEDLEDAKK 1403
Query: 113 QLKEAEQILATAVYQAKEKLKSIEKAR 139
+L Q A A+ A + S+E+AR
Sbjct: 1404 ELAIRLQEAAEAMGVANARNASLERAR 1430
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 35.8 bits (81), Expect = 0.040
Identities = 31/123 (25%), Positives = 58/123 (47%), Gaps = 13/123 (10%)
Query: 20 VAGGNSTRERLLSALEDLEVLSRELIEMLAISRNQKLLQAGEENQVLELLIHRDGEFQEL 79
V + E+ A+ D +++ EL + S + + ++ E V +L + D E
Sbjct: 1749 VQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLD----EA 1804
Query: 80 MKLALNQGKIHHEMQVLEKEVEKRDSDIQQLQKQ-------LKEAEQILATAVYQAKEKL 132
+LAL GK ++Q LE V + +S+++ QK L++ E+ + YQ +E
Sbjct: 1805 EQLALKGGK--KQIQKLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQTEEDR 1862
Query: 133 KSI 135
K+I
Sbjct: 1863 KNI 1865
Score = 28.5 bits (62), Expect = 6.5
Identities = 14/78 (17%), Positives = 41/78 (52%), Gaps = 4/78 (5%)
Query: 62 ENQVLELLIHRDGEFQELMKLALNQGKIHHEMQVLEKEVEKRDSDIQQLQKQLKEAEQIL 121
E+Q+ E+ + + + + +L+ + ++H E ++++++D+ + QL + +Q
Sbjct: 1257 EDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSR----GKQAF 1312
Query: 122 ATAVYQAKEKLKSIEKAR 139
+ + K +L+ KA+
Sbjct: 1313 TQQIEELKRQLEEETKAK 1330
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 35.4 bits (80), Expect = 0.053
Identities = 30/128 (23%), Positives = 64/128 (50%), Gaps = 11/128 (8%)
Query: 23 GNSTRERLLSALEDLEV---LSRELIEMLAISRNQKLLQAGEENQVLELLIHRDGEFQEL 79
G+ +E+ S ++++E S E+ +L Q+ L + EE + + E +E
Sbjct: 2206 GDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEE------REEEEEREE 2259
Query: 80 MKLALNQGKIHHEMQVLEKEVEKRDSDIQQLQKQLKEAEQILATAVYQAKEKLKSIEKAR 139
++ + + E + EK+VEK + + ++ +K+ K+ E V++ KE++ S E+
Sbjct: 2260 EEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETE 2319
Query: 140 KGAISSEE 147
++S EE
Sbjct: 2320 --SLSDEE 2325
Score = 28.9 bits (63), Expect = 4.9
Identities = 29/128 (22%), Positives = 59/128 (46%), Gaps = 5/128 (3%)
Query: 25 STRERLLSALEDLEVLSRELIEMLAISRNQKLLQAGEENQV----LELLIHRDGEFQELM 80
++R+R ++ +E E+ R+L I ++ + A EE+++ LE + Q
Sbjct: 1992 TSRQRKMTQVEQ-ELFERKLSLEEKILLHEDRILAMEESEIAKGKLEFTRGQRIFVQGQR 2050
Query: 81 KLALNQGKIHHEMQVLEKEVEKRDSDIQQLQKQLKEAEQILATAVYQAKEKLKSIEKARK 140
KLA K+ + + L KE K + ++ LQK ++ ++ + K K K R+
Sbjct: 2051 KLAKASRKLIKKRESLSKEPAKLNKILKALQKLTRDERKLTQEEIKMTKMKRALFVKERR 2110
Query: 141 GAISSEEI 148
+I ++
Sbjct: 2111 LSIEQSKL 2118
>gi|190194355 p90 autoantigen [Homo sapiens]
Length = 905
Score = 35.4 bits (80), Expect = 0.053
Identities = 35/140 (25%), Positives = 65/140 (46%), Gaps = 13/140 (9%)
Query: 26 TRERLLSALEDLEVLSRELIEMLAISRNQKLLQAGEENQVLELLIHRDGEFQEL-MKLAL 84
T + L +E ++ L+ L E S Q + + + +V L+ R+ + L K +
Sbjct: 751 TCDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQRKEVQNQLVDREHKLANLHQKTKV 810
Query: 85 NQGKIHHEMQVLEKEVEKRDSDIQQLQKQLKEAEQI--------LATAVYQAKEKLKSIE 136
+ KI + L+KE E ++ I L+K+L EQI + V +A+ + + E
Sbjct: 811 QEEKI----KTLQKEREDKEETIDILRKELSRTEQIRKELSIKASSLEVQKAQLEGRLEE 866
Query: 137 KARKGAISSEEIIKYAHRIS 156
K + EE+ K++H I+
Sbjct: 867 KESLVKLQQEELNKHSHMIA 886
Score = 29.3 bits (64), Expect = 3.8
Identities = 17/84 (20%), Positives = 42/84 (50%), Gaps = 6/84 (7%)
Query: 53 NQKLLQAGEENQVLELLIHRDGEFQELMKLALNQGKIHHEMQVLEKEVEKRDSDIQQLQK 112
N+KL EE+++L + EL++ + K + ++Q+ + K+ +++L +
Sbjct: 714 NRKLESVAEEHEILTK------SYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNE 767
Query: 113 QLKEAEQILATAVYQAKEKLKSIE 136
LKE + + + +E+ K ++
Sbjct: 768 SLKEQNEKSIAQLIEKEEQRKEVQ 791
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.128 0.350
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,625,008
Number of Sequences: 37866
Number of extensions: 500592
Number of successful extensions: 3663
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 72
Number of HSP's successfully gapped in prelim test: 330
Number of HSP's that attempted gapping in prelim test: 2908
Number of HSP's gapped (non-prelim): 1083
length of query: 270
length of database: 18,247,518
effective HSP length: 101
effective length of query: 169
effective length of database: 14,423,052
effective search space: 2437495788
effective search space used: 2437495788
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.