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Search of human proteins with 74315348
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|74315348 transient receptor potential cation channel,
subfamily V, member 1 [Homo sapiens]
(839 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|74315354 transient receptor potential cation channel, subfami... 1689 0.0
gi|74315352 transient receptor potential cation channel, subfami... 1689 0.0
gi|74315350 transient receptor potential cation channel, subfami... 1689 0.0
gi|74315348 transient receptor potential cation channel, subfami... 1689 0.0
gi|22547184 transient receptor potential cation channel, subfami... 685 0.0
gi|20127551 transient receptor potential cation channel, subfami... 631 0.0
gi|21735483 transient receptor potential cation channel, subfami... 543 e-154
gi|22547180 transient receptor potential cation channel, subfami... 372 e-102
gi|21314682 transient receptor potential cation channel, subfami... 242 9e-64
gi|17505200 transient receptor potential cation channel, subfami... 240 3e-63
gi|32967601 ankyrin 3 isoform 1 [Homo sapiens] 54 5e-07
gi|6912736 transient receptor potential cation channel, subfamil... 51 4e-06
gi|209863032 transient receptor potential cation channel, subfam... 50 7e-06
gi|209863030 transient receptor potential cation channel, subfam... 50 7e-06
gi|209863026 transient receptor potential cation channel, subfam... 50 7e-06
gi|209863024 transient receptor potential cation channel, subfam... 50 7e-06
gi|7706747 transient receptor potential cation channel, subfamil... 50 7e-06
gi|116063534 ankyrin repeat domain 27 (VPS9 domain) [Homo sapiens] 50 7e-06
gi|116534990 ankyrin-like protein 1 [Homo sapiens] 48 3e-05
gi|20270347 ankyrin repeat domain 54 [Homo sapiens] 48 4e-05
gi|188595682 ankyrin 2 isoform 3 [Homo sapiens] 47 7e-05
gi|52426737 ankyrin 2 isoform 2 [Homo sapiens] 47 7e-05
gi|52426735 ankyrin 2 isoform 1 [Homo sapiens] 47 7e-05
gi|4507685 transient receptor potential cation channel, subfamil... 46 1e-04
gi|215598574 ankyrin 1 isoform 9 [Homo sapiens] 46 1e-04
gi|70780359 ankyrin 1 isoform 1 [Homo sapiens] 46 1e-04
gi|70780357 ankyrin 1 isoform 3 [Homo sapiens] 46 1e-04
gi|70780355 ankyrin 1 isoform 2 [Homo sapiens] 46 1e-04
gi|70780353 ankyrin 1 isoform 4 [Homo sapiens] 46 1e-04
gi|209863028 transient receptor potential cation channel, subfam... 46 2e-04
>gi|74315354 transient receptor potential cation channel, subfamily
V, member 1 [Homo sapiens]
Length = 839
Score = 1689 bits (4375), Expect = 0.0
Identities = 839/839 (100%), Positives = 839/839 (100%)
Query: 1 MKKWSSTDLGAAADPLQKDTCPDPLDGDPNSRPPPAKPQLSTAKSRTRLFGKGDSEEAFP 60
MKKWSSTDLGAAADPLQKDTCPDPLDGDPNSRPPPAKPQLSTAKSRTRLFGKGDSEEAFP
Sbjct: 1 MKKWSSTDLGAAADPLQKDTCPDPLDGDPNSRPPPAKPQLSTAKSRTRLFGKGDSEEAFP 60
Query: 61 VDCPHEEGELDSCPTITVSPVITIQRPGDGPTGARLLSQDSVAASTEKTLRLYDRRSIFE 120
VDCPHEEGELDSCPTITVSPVITIQRPGDGPTGARLLSQDSVAASTEKTLRLYDRRSIFE
Sbjct: 61 VDCPHEEGELDSCPTITVSPVITIQRPGDGPTGARLLSQDSVAASTEKTLRLYDRRSIFE 120
Query: 121 AVAQNNCQDLESLLLFLQKSKKHLTDNEFKDPETGKTCLLKAMLNLHDGQNTTIPLLLEI 180
AVAQNNCQDLESLLLFLQKSKKHLTDNEFKDPETGKTCLLKAMLNLHDGQNTTIPLLLEI
Sbjct: 121 AVAQNNCQDLESLLLFLQKSKKHLTDNEFKDPETGKTCLLKAMLNLHDGQNTTIPLLLEI 180
Query: 181 ARQTDSLKELVNASYTDSYYKGQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKT 240
ARQTDSLKELVNASYTDSYYKGQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKT
Sbjct: 181 ARQTDSLKELVNASYTDSYYKGQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKT 240
Query: 241 KGRPGFYFGELPLSLAACTNQLGIVKFLLQNSWQTADISARDSVGNTVLHALVEVADNTA 300
KGRPGFYFGELPLSLAACTNQLGIVKFLLQNSWQTADISARDSVGNTVLHALVEVADNTA
Sbjct: 241 KGRPGFYFGELPLSLAACTNQLGIVKFLLQNSWQTADISARDSVGNTVLHALVEVADNTA 300
Query: 301 DNTKFVTSMYNEILMLGAKLHPTLKLEELTNKKGMTPLALAAGTGKIGVLAYILQREIQE 360
DNTKFVTSMYNEILMLGAKLHPTLKLEELTNKKGMTPLALAAGTGKIGVLAYILQREIQE
Sbjct: 301 DNTKFVTSMYNEILMLGAKLHPTLKLEELTNKKGMTPLALAAGTGKIGVLAYILQREIQE 360
Query: 361 PECRHLSRKFTEWAYGPVHSSLYDLSCIDTCEKNSVLEVIAYSSSETPNRHDMLLVEPLN 420
PECRHLSRKFTEWAYGPVHSSLYDLSCIDTCEKNSVLEVIAYSSSETPNRHDMLLVEPLN
Sbjct: 361 PECRHLSRKFTEWAYGPVHSSLYDLSCIDTCEKNSVLEVIAYSSSETPNRHDMLLVEPLN 420
Query: 421 RLLQDKWDRFVKRIFYFNFLVYCLYMIIFTMAAYYRPVDGLPPFKMEKTGDYFRVTGEIL 480
RLLQDKWDRFVKRIFYFNFLVYCLYMIIFTMAAYYRPVDGLPPFKMEKTGDYFRVTGEIL
Sbjct: 421 RLLQDKWDRFVKRIFYFNFLVYCLYMIIFTMAAYYRPVDGLPPFKMEKTGDYFRVTGEIL 480
Query: 481 SVLGGVYFFFRGIQYFLQRRPSMKTLFVDSYSEMLFFLQSLFMLATVVLYFSHLKEYVAS 540
SVLGGVYFFFRGIQYFLQRRPSMKTLFVDSYSEMLFFLQSLFMLATVVLYFSHLKEYVAS
Sbjct: 481 SVLGGVYFFFRGIQYFLQRRPSMKTLFVDSYSEMLFFLQSLFMLATVVLYFSHLKEYVAS 540
Query: 541 MVFSLALGWTNMLYYTRGFQQMGIYAVMIEKMILRDLCRFMFVYIVFLFGFSTAVVTLIE 600
MVFSLALGWTNMLYYTRGFQQMGIYAVMIEKMILRDLCRFMFVYIVFLFGFSTAVVTLIE
Sbjct: 541 MVFSLALGWTNMLYYTRGFQQMGIYAVMIEKMILRDLCRFMFVYIVFLFGFSTAVVTLIE 600
Query: 601 DGKNDSLPSESTSHRWRGPACRPPDSSYNSLYSTCLELFKFTIGMGDLEFTENYDFKAVF 660
DGKNDSLPSESTSHRWRGPACRPPDSSYNSLYSTCLELFKFTIGMGDLEFTENYDFKAVF
Sbjct: 601 DGKNDSLPSESTSHRWRGPACRPPDSSYNSLYSTCLELFKFTIGMGDLEFTENYDFKAVF 660
Query: 661 IILLLAYVILTYILLLNMLIALMGETVNKIAQESKNIWKLQRAITILDTEKSFLKCMRKA 720
IILLLAYVILTYILLLNMLIALMGETVNKIAQESKNIWKLQRAITILDTEKSFLKCMRKA
Sbjct: 661 IILLLAYVILTYILLLNMLIALMGETVNKIAQESKNIWKLQRAITILDTEKSFLKCMRKA 720
Query: 721 FRSGKLLQVGYTPDGKDDYRWCFRVDEVNWTTWNTNVGIINEDPGNCEGVKRTLSFSLRS 780
FRSGKLLQVGYTPDGKDDYRWCFRVDEVNWTTWNTNVGIINEDPGNCEGVKRTLSFSLRS
Sbjct: 721 FRSGKLLQVGYTPDGKDDYRWCFRVDEVNWTTWNTNVGIINEDPGNCEGVKRTLSFSLRS 780
Query: 781 SRVSGRHWKNFALVPLLREASARDRQSAQPEEVYLRQFSGSLKPEDAEVFKSPAASGEK 839
SRVSGRHWKNFALVPLLREASARDRQSAQPEEVYLRQFSGSLKPEDAEVFKSPAASGEK
Sbjct: 781 SRVSGRHWKNFALVPLLREASARDRQSAQPEEVYLRQFSGSLKPEDAEVFKSPAASGEK 839
>gi|74315352 transient receptor potential cation channel, subfamily
V, member 1 [Homo sapiens]
Length = 839
Score = 1689 bits (4375), Expect = 0.0
Identities = 839/839 (100%), Positives = 839/839 (100%)
Query: 1 MKKWSSTDLGAAADPLQKDTCPDPLDGDPNSRPPPAKPQLSTAKSRTRLFGKGDSEEAFP 60
MKKWSSTDLGAAADPLQKDTCPDPLDGDPNSRPPPAKPQLSTAKSRTRLFGKGDSEEAFP
Sbjct: 1 MKKWSSTDLGAAADPLQKDTCPDPLDGDPNSRPPPAKPQLSTAKSRTRLFGKGDSEEAFP 60
Query: 61 VDCPHEEGELDSCPTITVSPVITIQRPGDGPTGARLLSQDSVAASTEKTLRLYDRRSIFE 120
VDCPHEEGELDSCPTITVSPVITIQRPGDGPTGARLLSQDSVAASTEKTLRLYDRRSIFE
Sbjct: 61 VDCPHEEGELDSCPTITVSPVITIQRPGDGPTGARLLSQDSVAASTEKTLRLYDRRSIFE 120
Query: 121 AVAQNNCQDLESLLLFLQKSKKHLTDNEFKDPETGKTCLLKAMLNLHDGQNTTIPLLLEI 180
AVAQNNCQDLESLLLFLQKSKKHLTDNEFKDPETGKTCLLKAMLNLHDGQNTTIPLLLEI
Sbjct: 121 AVAQNNCQDLESLLLFLQKSKKHLTDNEFKDPETGKTCLLKAMLNLHDGQNTTIPLLLEI 180
Query: 181 ARQTDSLKELVNASYTDSYYKGQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKT 240
ARQTDSLKELVNASYTDSYYKGQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKT
Sbjct: 181 ARQTDSLKELVNASYTDSYYKGQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKT 240
Query: 241 KGRPGFYFGELPLSLAACTNQLGIVKFLLQNSWQTADISARDSVGNTVLHALVEVADNTA 300
KGRPGFYFGELPLSLAACTNQLGIVKFLLQNSWQTADISARDSVGNTVLHALVEVADNTA
Sbjct: 241 KGRPGFYFGELPLSLAACTNQLGIVKFLLQNSWQTADISARDSVGNTVLHALVEVADNTA 300
Query: 301 DNTKFVTSMYNEILMLGAKLHPTLKLEELTNKKGMTPLALAAGTGKIGVLAYILQREIQE 360
DNTKFVTSMYNEILMLGAKLHPTLKLEELTNKKGMTPLALAAGTGKIGVLAYILQREIQE
Sbjct: 301 DNTKFVTSMYNEILMLGAKLHPTLKLEELTNKKGMTPLALAAGTGKIGVLAYILQREIQE 360
Query: 361 PECRHLSRKFTEWAYGPVHSSLYDLSCIDTCEKNSVLEVIAYSSSETPNRHDMLLVEPLN 420
PECRHLSRKFTEWAYGPVHSSLYDLSCIDTCEKNSVLEVIAYSSSETPNRHDMLLVEPLN
Sbjct: 361 PECRHLSRKFTEWAYGPVHSSLYDLSCIDTCEKNSVLEVIAYSSSETPNRHDMLLVEPLN 420
Query: 421 RLLQDKWDRFVKRIFYFNFLVYCLYMIIFTMAAYYRPVDGLPPFKMEKTGDYFRVTGEIL 480
RLLQDKWDRFVKRIFYFNFLVYCLYMIIFTMAAYYRPVDGLPPFKMEKTGDYFRVTGEIL
Sbjct: 421 RLLQDKWDRFVKRIFYFNFLVYCLYMIIFTMAAYYRPVDGLPPFKMEKTGDYFRVTGEIL 480
Query: 481 SVLGGVYFFFRGIQYFLQRRPSMKTLFVDSYSEMLFFLQSLFMLATVVLYFSHLKEYVAS 540
SVLGGVYFFFRGIQYFLQRRPSMKTLFVDSYSEMLFFLQSLFMLATVVLYFSHLKEYVAS
Sbjct: 481 SVLGGVYFFFRGIQYFLQRRPSMKTLFVDSYSEMLFFLQSLFMLATVVLYFSHLKEYVAS 540
Query: 541 MVFSLALGWTNMLYYTRGFQQMGIYAVMIEKMILRDLCRFMFVYIVFLFGFSTAVVTLIE 600
MVFSLALGWTNMLYYTRGFQQMGIYAVMIEKMILRDLCRFMFVYIVFLFGFSTAVVTLIE
Sbjct: 541 MVFSLALGWTNMLYYTRGFQQMGIYAVMIEKMILRDLCRFMFVYIVFLFGFSTAVVTLIE 600
Query: 601 DGKNDSLPSESTSHRWRGPACRPPDSSYNSLYSTCLELFKFTIGMGDLEFTENYDFKAVF 660
DGKNDSLPSESTSHRWRGPACRPPDSSYNSLYSTCLELFKFTIGMGDLEFTENYDFKAVF
Sbjct: 601 DGKNDSLPSESTSHRWRGPACRPPDSSYNSLYSTCLELFKFTIGMGDLEFTENYDFKAVF 660
Query: 661 IILLLAYVILTYILLLNMLIALMGETVNKIAQESKNIWKLQRAITILDTEKSFLKCMRKA 720
IILLLAYVILTYILLLNMLIALMGETVNKIAQESKNIWKLQRAITILDTEKSFLKCMRKA
Sbjct: 661 IILLLAYVILTYILLLNMLIALMGETVNKIAQESKNIWKLQRAITILDTEKSFLKCMRKA 720
Query: 721 FRSGKLLQVGYTPDGKDDYRWCFRVDEVNWTTWNTNVGIINEDPGNCEGVKRTLSFSLRS 780
FRSGKLLQVGYTPDGKDDYRWCFRVDEVNWTTWNTNVGIINEDPGNCEGVKRTLSFSLRS
Sbjct: 721 FRSGKLLQVGYTPDGKDDYRWCFRVDEVNWTTWNTNVGIINEDPGNCEGVKRTLSFSLRS 780
Query: 781 SRVSGRHWKNFALVPLLREASARDRQSAQPEEVYLRQFSGSLKPEDAEVFKSPAASGEK 839
SRVSGRHWKNFALVPLLREASARDRQSAQPEEVYLRQFSGSLKPEDAEVFKSPAASGEK
Sbjct: 781 SRVSGRHWKNFALVPLLREASARDRQSAQPEEVYLRQFSGSLKPEDAEVFKSPAASGEK 839
>gi|74315350 transient receptor potential cation channel, subfamily
V, member 1 [Homo sapiens]
Length = 839
Score = 1689 bits (4375), Expect = 0.0
Identities = 839/839 (100%), Positives = 839/839 (100%)
Query: 1 MKKWSSTDLGAAADPLQKDTCPDPLDGDPNSRPPPAKPQLSTAKSRTRLFGKGDSEEAFP 60
MKKWSSTDLGAAADPLQKDTCPDPLDGDPNSRPPPAKPQLSTAKSRTRLFGKGDSEEAFP
Sbjct: 1 MKKWSSTDLGAAADPLQKDTCPDPLDGDPNSRPPPAKPQLSTAKSRTRLFGKGDSEEAFP 60
Query: 61 VDCPHEEGELDSCPTITVSPVITIQRPGDGPTGARLLSQDSVAASTEKTLRLYDRRSIFE 120
VDCPHEEGELDSCPTITVSPVITIQRPGDGPTGARLLSQDSVAASTEKTLRLYDRRSIFE
Sbjct: 61 VDCPHEEGELDSCPTITVSPVITIQRPGDGPTGARLLSQDSVAASTEKTLRLYDRRSIFE 120
Query: 121 AVAQNNCQDLESLLLFLQKSKKHLTDNEFKDPETGKTCLLKAMLNLHDGQNTTIPLLLEI 180
AVAQNNCQDLESLLLFLQKSKKHLTDNEFKDPETGKTCLLKAMLNLHDGQNTTIPLLLEI
Sbjct: 121 AVAQNNCQDLESLLLFLQKSKKHLTDNEFKDPETGKTCLLKAMLNLHDGQNTTIPLLLEI 180
Query: 181 ARQTDSLKELVNASYTDSYYKGQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKT 240
ARQTDSLKELVNASYTDSYYKGQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKT
Sbjct: 181 ARQTDSLKELVNASYTDSYYKGQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKT 240
Query: 241 KGRPGFYFGELPLSLAACTNQLGIVKFLLQNSWQTADISARDSVGNTVLHALVEVADNTA 300
KGRPGFYFGELPLSLAACTNQLGIVKFLLQNSWQTADISARDSVGNTVLHALVEVADNTA
Sbjct: 241 KGRPGFYFGELPLSLAACTNQLGIVKFLLQNSWQTADISARDSVGNTVLHALVEVADNTA 300
Query: 301 DNTKFVTSMYNEILMLGAKLHPTLKLEELTNKKGMTPLALAAGTGKIGVLAYILQREIQE 360
DNTKFVTSMYNEILMLGAKLHPTLKLEELTNKKGMTPLALAAGTGKIGVLAYILQREIQE
Sbjct: 301 DNTKFVTSMYNEILMLGAKLHPTLKLEELTNKKGMTPLALAAGTGKIGVLAYILQREIQE 360
Query: 361 PECRHLSRKFTEWAYGPVHSSLYDLSCIDTCEKNSVLEVIAYSSSETPNRHDMLLVEPLN 420
PECRHLSRKFTEWAYGPVHSSLYDLSCIDTCEKNSVLEVIAYSSSETPNRHDMLLVEPLN
Sbjct: 361 PECRHLSRKFTEWAYGPVHSSLYDLSCIDTCEKNSVLEVIAYSSSETPNRHDMLLVEPLN 420
Query: 421 RLLQDKWDRFVKRIFYFNFLVYCLYMIIFTMAAYYRPVDGLPPFKMEKTGDYFRVTGEIL 480
RLLQDKWDRFVKRIFYFNFLVYCLYMIIFTMAAYYRPVDGLPPFKMEKTGDYFRVTGEIL
Sbjct: 421 RLLQDKWDRFVKRIFYFNFLVYCLYMIIFTMAAYYRPVDGLPPFKMEKTGDYFRVTGEIL 480
Query: 481 SVLGGVYFFFRGIQYFLQRRPSMKTLFVDSYSEMLFFLQSLFMLATVVLYFSHLKEYVAS 540
SVLGGVYFFFRGIQYFLQRRPSMKTLFVDSYSEMLFFLQSLFMLATVVLYFSHLKEYVAS
Sbjct: 481 SVLGGVYFFFRGIQYFLQRRPSMKTLFVDSYSEMLFFLQSLFMLATVVLYFSHLKEYVAS 540
Query: 541 MVFSLALGWTNMLYYTRGFQQMGIYAVMIEKMILRDLCRFMFVYIVFLFGFSTAVVTLIE 600
MVFSLALGWTNMLYYTRGFQQMGIYAVMIEKMILRDLCRFMFVYIVFLFGFSTAVVTLIE
Sbjct: 541 MVFSLALGWTNMLYYTRGFQQMGIYAVMIEKMILRDLCRFMFVYIVFLFGFSTAVVTLIE 600
Query: 601 DGKNDSLPSESTSHRWRGPACRPPDSSYNSLYSTCLELFKFTIGMGDLEFTENYDFKAVF 660
DGKNDSLPSESTSHRWRGPACRPPDSSYNSLYSTCLELFKFTIGMGDLEFTENYDFKAVF
Sbjct: 601 DGKNDSLPSESTSHRWRGPACRPPDSSYNSLYSTCLELFKFTIGMGDLEFTENYDFKAVF 660
Query: 661 IILLLAYVILTYILLLNMLIALMGETVNKIAQESKNIWKLQRAITILDTEKSFLKCMRKA 720
IILLLAYVILTYILLLNMLIALMGETVNKIAQESKNIWKLQRAITILDTEKSFLKCMRKA
Sbjct: 661 IILLLAYVILTYILLLNMLIALMGETVNKIAQESKNIWKLQRAITILDTEKSFLKCMRKA 720
Query: 721 FRSGKLLQVGYTPDGKDDYRWCFRVDEVNWTTWNTNVGIINEDPGNCEGVKRTLSFSLRS 780
FRSGKLLQVGYTPDGKDDYRWCFRVDEVNWTTWNTNVGIINEDPGNCEGVKRTLSFSLRS
Sbjct: 721 FRSGKLLQVGYTPDGKDDYRWCFRVDEVNWTTWNTNVGIINEDPGNCEGVKRTLSFSLRS 780
Query: 781 SRVSGRHWKNFALVPLLREASARDRQSAQPEEVYLRQFSGSLKPEDAEVFKSPAASGEK 839
SRVSGRHWKNFALVPLLREASARDRQSAQPEEVYLRQFSGSLKPEDAEVFKSPAASGEK
Sbjct: 781 SRVSGRHWKNFALVPLLREASARDRQSAQPEEVYLRQFSGSLKPEDAEVFKSPAASGEK 839
>gi|74315348 transient receptor potential cation channel, subfamily
V, member 1 [Homo sapiens]
Length = 839
Score = 1689 bits (4375), Expect = 0.0
Identities = 839/839 (100%), Positives = 839/839 (100%)
Query: 1 MKKWSSTDLGAAADPLQKDTCPDPLDGDPNSRPPPAKPQLSTAKSRTRLFGKGDSEEAFP 60
MKKWSSTDLGAAADPLQKDTCPDPLDGDPNSRPPPAKPQLSTAKSRTRLFGKGDSEEAFP
Sbjct: 1 MKKWSSTDLGAAADPLQKDTCPDPLDGDPNSRPPPAKPQLSTAKSRTRLFGKGDSEEAFP 60
Query: 61 VDCPHEEGELDSCPTITVSPVITIQRPGDGPTGARLLSQDSVAASTEKTLRLYDRRSIFE 120
VDCPHEEGELDSCPTITVSPVITIQRPGDGPTGARLLSQDSVAASTEKTLRLYDRRSIFE
Sbjct: 61 VDCPHEEGELDSCPTITVSPVITIQRPGDGPTGARLLSQDSVAASTEKTLRLYDRRSIFE 120
Query: 121 AVAQNNCQDLESLLLFLQKSKKHLTDNEFKDPETGKTCLLKAMLNLHDGQNTTIPLLLEI 180
AVAQNNCQDLESLLLFLQKSKKHLTDNEFKDPETGKTCLLKAMLNLHDGQNTTIPLLLEI
Sbjct: 121 AVAQNNCQDLESLLLFLQKSKKHLTDNEFKDPETGKTCLLKAMLNLHDGQNTTIPLLLEI 180
Query: 181 ARQTDSLKELVNASYTDSYYKGQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKT 240
ARQTDSLKELVNASYTDSYYKGQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKT
Sbjct: 181 ARQTDSLKELVNASYTDSYYKGQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKT 240
Query: 241 KGRPGFYFGELPLSLAACTNQLGIVKFLLQNSWQTADISARDSVGNTVLHALVEVADNTA 300
KGRPGFYFGELPLSLAACTNQLGIVKFLLQNSWQTADISARDSVGNTVLHALVEVADNTA
Sbjct: 241 KGRPGFYFGELPLSLAACTNQLGIVKFLLQNSWQTADISARDSVGNTVLHALVEVADNTA 300
Query: 301 DNTKFVTSMYNEILMLGAKLHPTLKLEELTNKKGMTPLALAAGTGKIGVLAYILQREIQE 360
DNTKFVTSMYNEILMLGAKLHPTLKLEELTNKKGMTPLALAAGTGKIGVLAYILQREIQE
Sbjct: 301 DNTKFVTSMYNEILMLGAKLHPTLKLEELTNKKGMTPLALAAGTGKIGVLAYILQREIQE 360
Query: 361 PECRHLSRKFTEWAYGPVHSSLYDLSCIDTCEKNSVLEVIAYSSSETPNRHDMLLVEPLN 420
PECRHLSRKFTEWAYGPVHSSLYDLSCIDTCEKNSVLEVIAYSSSETPNRHDMLLVEPLN
Sbjct: 361 PECRHLSRKFTEWAYGPVHSSLYDLSCIDTCEKNSVLEVIAYSSSETPNRHDMLLVEPLN 420
Query: 421 RLLQDKWDRFVKRIFYFNFLVYCLYMIIFTMAAYYRPVDGLPPFKMEKTGDYFRVTGEIL 480
RLLQDKWDRFVKRIFYFNFLVYCLYMIIFTMAAYYRPVDGLPPFKMEKTGDYFRVTGEIL
Sbjct: 421 RLLQDKWDRFVKRIFYFNFLVYCLYMIIFTMAAYYRPVDGLPPFKMEKTGDYFRVTGEIL 480
Query: 481 SVLGGVYFFFRGIQYFLQRRPSMKTLFVDSYSEMLFFLQSLFMLATVVLYFSHLKEYVAS 540
SVLGGVYFFFRGIQYFLQRRPSMKTLFVDSYSEMLFFLQSLFMLATVVLYFSHLKEYVAS
Sbjct: 481 SVLGGVYFFFRGIQYFLQRRPSMKTLFVDSYSEMLFFLQSLFMLATVVLYFSHLKEYVAS 540
Query: 541 MVFSLALGWTNMLYYTRGFQQMGIYAVMIEKMILRDLCRFMFVYIVFLFGFSTAVVTLIE 600
MVFSLALGWTNMLYYTRGFQQMGIYAVMIEKMILRDLCRFMFVYIVFLFGFSTAVVTLIE
Sbjct: 541 MVFSLALGWTNMLYYTRGFQQMGIYAVMIEKMILRDLCRFMFVYIVFLFGFSTAVVTLIE 600
Query: 601 DGKNDSLPSESTSHRWRGPACRPPDSSYNSLYSTCLELFKFTIGMGDLEFTENYDFKAVF 660
DGKNDSLPSESTSHRWRGPACRPPDSSYNSLYSTCLELFKFTIGMGDLEFTENYDFKAVF
Sbjct: 601 DGKNDSLPSESTSHRWRGPACRPPDSSYNSLYSTCLELFKFTIGMGDLEFTENYDFKAVF 660
Query: 661 IILLLAYVILTYILLLNMLIALMGETVNKIAQESKNIWKLQRAITILDTEKSFLKCMRKA 720
IILLLAYVILTYILLLNMLIALMGETVNKIAQESKNIWKLQRAITILDTEKSFLKCMRKA
Sbjct: 661 IILLLAYVILTYILLLNMLIALMGETVNKIAQESKNIWKLQRAITILDTEKSFLKCMRKA 720
Query: 721 FRSGKLLQVGYTPDGKDDYRWCFRVDEVNWTTWNTNVGIINEDPGNCEGVKRTLSFSLRS 780
FRSGKLLQVGYTPDGKDDYRWCFRVDEVNWTTWNTNVGIINEDPGNCEGVKRTLSFSLRS
Sbjct: 721 FRSGKLLQVGYTPDGKDDYRWCFRVDEVNWTTWNTNVGIINEDPGNCEGVKRTLSFSLRS 780
Query: 781 SRVSGRHWKNFALVPLLREASARDRQSAQPEEVYLRQFSGSLKPEDAEVFKSPAASGEK 839
SRVSGRHWKNFALVPLLREASARDRQSAQPEEVYLRQFSGSLKPEDAEVFKSPAASGEK
Sbjct: 781 SRVSGRHWKNFALVPLLREASARDRQSAQPEEVYLRQFSGSLKPEDAEVFKSPAASGEK 839
>gi|22547184 transient receptor potential cation channel, subfamily
V, member 4 isoform a [Homo sapiens]
Length = 871
Score = 685 bits (1768), Expect = 0.0
Identities = 352/708 (49%), Positives = 498/708 (70%), Gaps = 16/708 (2%)
Query: 110 LRLYDRRSIFEAVAQNNCQDLESLLLFLQKSKKHLTDNEFKDPETGKTCLLKAMLNLHDG 169
L++++R +F+ V++ + DL+ LL FL KK LTD EF++P TGKTCL KA+LNL +G
Sbjct: 146 LKVFNRPILFDIVSRGSTADLDGLLPFLLTHKKRLTDEEFREPSTGKTCLPKALLNLSNG 205
Query: 170 QNTTIPLLLEIARQTDSLKELVNASYTDSYYKGQTALHIAIERRNMALVTLLVENGADVQ 229
+N TIP+LL+IA +T +++E +N+ + D YY+GQTALHIAIERR V LLV GADV
Sbjct: 206 RNDTIPVLLDIAERTGNMREFINSPFRDIYYRGQTALHIAIERRCKHYVELLVAQGADVH 265
Query: 230 AAAHGDFFKKTKGRPGFYFGELPLSLAACTNQLGIVKFLLQNSWQTADISARDSVGNTVL 289
A A G FF+ FYFGELPLSLAACTNQ IV +L +N + AD+ +DS GNTVL
Sbjct: 266 AQARGRFFQPKDEGGYFYFGELPLSLAACTNQPHIVNYLTENPHKKADMRRQDSRGNTVL 325
Query: 290 HALVEVADNTADNTKFVTSMYNEILMLGAKLHPTLKLEELTNKKGMTPLALAAGTGKIGV 349
HALV +ADNT +NTKFVT MY+ +L+ A+L P LE + N G++PL +AA TGKIG+
Sbjct: 326 HALVAIADNTRENTKFVTKMYDLLLLKCARLFPDSNLEAVLNNDGLSPLMMAAKTGKIGI 385
Query: 350 LAYILQREIQEPECRHLSRKFTEWAYGPVHSSLYDLSCIDTC-EKNSVLEVIAYSSSETP 408
+I++RE+ + + RHLSRKF +WAYGPV+SSLYDLS +DTC E+ SVLE++ Y +S+
Sbjct: 386 FQHIIRREVTDEDTRHLSRKFKDWAYGPVYSSLYDLSSLDTCGEEASVLEILVY-NSKIE 444
Query: 409 NRHDMLLVEPLNRLLQDKWDRFVKRIFYFNFLVYCLYMIIFTMAAYYRPVDGLPPFKMEK 468
NRH+ML VEP+N LL+DKW +F FY N + Y M+IFT+ AYY+P++G PP+
Sbjct: 445 NRHEMLAVEPINELLRDKWRKFGAVSFYINVVSYLCAMVIFTLTAYYQPLEGTPPYPYRT 504
Query: 469 TGDYFRVTGEILSVLGGVYFFFRGIQ-YFLQRRPSMKTLFVDSYSEMLFFLQSLFMLATV 527
T DY R+ GE++++ GV FFF I+ F+++ P + +LF+D ++L+F+ S+ ++ +
Sbjct: 505 TVDYLRLAGEVITLFTGVLFFFTNIKDLFMKKCPGVNSLFIDGSFQLLYFIYSVLVIVSA 564
Query: 528 VLYFSHLKEYVASMVFSLALGWTNMLYYTRGFQQMGIYAVMIEKMILRDLCRFMFVYIVF 587
LY + ++ Y+A MVF+L LGW N LY+TRG + G Y++MI+K++ +DL RF+ VY++F
Sbjct: 565 ALYLAGIEAYLAVMVFALVLGWMNALYFTRGLKLTGTYSIMIQKILFKDLFRFLLVYLLF 624
Query: 588 LFGFSTAVVTLIEDGKNDSLPSESTSHRW--RGPACRPPDSSYNSLYSTCLELFKFTIGM 645
+ G+++A+V+L+ N + +E ++ P+CR DS S + L+LFK TIGM
Sbjct: 625 MIGYASALVSLLNPCANMKVCNEDQTNCTVPTYPSCR--DSETFSTF--LLDLFKLTIGM 680
Query: 646 GDLEFTENYDFKAVFIILLLAYVILTYILLLNMLIALMGETVNKIAQESKNIWKLQRAIT 705
GDLE + + VFIILL+ Y+ILT++LLLNMLIALMGETV ++++ESK+IWKLQ A T
Sbjct: 681 GDLEMLSSTKYPVVFIILLVTYIILTFVLLLNMLIALMGETVGQVSKESKHIWKLQWATT 740
Query: 706 ILDTEKSFLKCMRKAFRSGKLLQVGYTPDGKDDYRWCFRVDEVNWTTWNTNVGIINEDPG 765
ILD E+SF +RKAFRSG+++ VG + DG D RWCFRVDEVNW+ WN N+GIINEDPG
Sbjct: 741 ILDIERSFPVFLRKAFRSGEMVTVGKSSDGTPDRRWCFRVDEVNWSHWNQNLGIINEDPG 800
Query: 766 NCEGVKRTLSFSLRSSRVSGRHWKNFALVPLLREASARDRQSAQPEEV 813
E + FS R+ W ++VP + E + +++ P+EV
Sbjct: 801 KNE-TYQYYGFSHTVGRLRRDRWS--SVVPRVVELN----KNSNPDEV 841
>gi|20127551 transient receptor potential cation channel, subfamily
V, member 2 [Homo sapiens]
Length = 764
Score = 631 bits (1627), Expect = 0.0
Identities = 343/697 (49%), Positives = 464/697 (66%), Gaps = 19/697 (2%)
Query: 113 YDRRSIFEAVAQNNCQDLESLLLFLQKSKKHLTDNEFKDPETGKTCLLKAMLNLHDGQNT 172
+DR +F AV++ +DL L +L K+ K+LTD+E+ + TGKTCL+KA+LNL DG N
Sbjct: 74 FDRDRLFNAVSRGVPEDLAGLPEYLSKTSKYLTDSEYTEGSTGKTCLMKAVLNLKDGVNA 133
Query: 173 TIPLLLEIARQTDSLKELVNASYTDSYYKGQTALHIAIERRNMALVTLLVENGADVQAAA 232
I LL+I R + + + LVNA TD YY+G +ALHIAIE+R++ V LLVENGA+V A A
Sbjct: 134 CILPLLQIDRDSGNPQPLVNAQCTDDYYRGHSALHIAIEKRSLQCVKLLVENGANVHARA 193
Query: 233 HGDFFKKTKGRPGFYFGELPLSLAACTNQLGIVKFLLQNSWQTADISARDSVGNTVLHAL 292
G FF+K +G FYFGELPLSLAACT Q +V +LL+N Q A + A DS GNTVLHAL
Sbjct: 194 CGRFFQKGQGTC-FYFGELPLSLAACTKQWDVVSYLLENPHQPASLQATDSQGNTVLHAL 252
Query: 293 VEVADNTADNTKFVTSMYNEILMLGAKLHPTLKLEELTNKKGMTPLALAAGTGKIGVLAY 352
V ++DN+A+N VTSMY+ +L GA+L PT++LE++ N + +TPL LAA GKI + +
Sbjct: 253 VMISDNSAENIALVTSMYDGLLQAGARLCPTVQLEDIRNLQDLTPLKLAAKEGKIEIFRH 312
Query: 353 ILQREIQEPECRHLSRKFTEWAYGPVHSSLYDLSCIDTCEKNSVLEVIAYSSSETPNRHD 412
ILQRE HLSRKFTEW YGPV SLYDL+ +D+CE+NSVLE+IA+ ++P+RH
Sbjct: 313 ILQREFSG--LSHLSRKFTEWCYGPVRVSLYDLASVDSCEENSVLEIIAFHC-KSPHRHR 369
Query: 413 MLLVEPLNRLLQDKWDRFVKRIFYFNFLVYCLYMIIFTMAAYYRPV---DGLPPFKMEKT 469
M+++EPLN+LLQ KWD + + F+ NFL +YM IFT AY++P P K E
Sbjct: 370 MVVLEPLNKLLQAKWDLLIPK-FFLNFLCNLIYMFIFTAVAYHQPTLKKQAAPHLKAE-V 427
Query: 470 GDYFRVTGEILSVLGGVYFFFRGIQYFLQRRPSMKTLFVDSYSEMLFFLQSLFMLATVVL 529
G+ +TG IL +LGG+Y + YF +R + F+DSY E+LF Q+L + + VL
Sbjct: 428 GNSMLLTGHILILLGGIYLLVGQLWYFWRRHVFIWISFIDSYFEILFLFQALLTVVSQVL 487
Query: 530 YFSHLKEYVASMVFSLALGWTNMLYYTRGFQQMGIYAVMIEKMILRDLCRFMFVYIVFLF 589
F ++ Y+ +V +L LGW N+LYYTRGFQ GIY+VMI+K+ILRDL RF+ +Y+VFLF
Sbjct: 488 CFLAIEWYLPLLVSALVLGWLNLLYYTRGFQHTGIYSVMIQKVILRDLLRFLLIYLVFLF 547
Query: 590 GFSTAVVTLIEDGKNDSLPSESTSHRWRGPACRPPD----SSYNSLYSTCLELFKFTIGM 645
GF+ A+V+L ++ P+ + P D + Y + LELFKFTIGM
Sbjct: 548 GFAVALVSLSQEAWRPEAPTGPNATESVQPMEGQEDEGNGAQYRGILEASLELFKFTIGM 607
Query: 646 GDLEFTENYDFKAVFIILLLAYVILTYILLLNMLIALMGETVNKIAQESKNIWKLQRAIT 705
G+L F E F+ + ++LLLAYV+LTYILLLNMLIALM ETVN +A +S +IWKLQ+AI+
Sbjct: 608 GELAFQEQLHFRGMVLLLLLAYVLLTYILLLNMLIALMSETVNSVATDSWSIWKLQKAIS 667
Query: 706 ILDTEKSFLKCMRKAFRSGKLLQVGYTPDGKDDYRWCFRVDEVNWTTWNTNVGIINEDPG 765
+L+ E + C RK R+G +L VG PDG D RWCFRV+EVNW +W + + EDP
Sbjct: 668 VLEMENGYWWC-RKKQRAGVMLTVGTKPDGSPDERWCFRVEEVNWASWEQTLPTLCEDPS 726
Query: 766 NCEGVKRTLSFSLRSS----RVSGRHWKNFALVPLLR 798
GV RTL + +S G +N+ V LL+
Sbjct: 727 GA-GVPRTLENPVLASPPKEDEDGASEENYVPVQLLQ 762
>gi|21735483 transient receptor potential cation channel, subfamily
V, member 3 [Homo sapiens]
Length = 790
Score = 543 bits (1398), Expect = e-154
Identities = 295/663 (44%), Positives = 414/663 (62%), Gaps = 40/663 (6%)
Query: 115 RRSIFEAVAQNNCQDLESLLLFLQKSKKHLTDNEFKD--------PETGKTCLLKAMLNL 166
++ IF AV++ ++L LL+ LQ+ + D + D +TGKTCL+KA+LN+
Sbjct: 120 KKRIFAAVSEGCVEELVELLVELQELCRRRHDEDVPDFLMHKLTASDTGKTCLMKALLNI 179
Query: 167 HDGQNTTIPLLLEIARQTDSLKELVNASYTDSYYKGQTALHIAIERRNMALVTLLVENGA 226
+ + +LL A + D L +NA YT+ Y+GQTAL+IAIERR + LL+ GA
Sbjct: 180 NPNTKEIVRILLAFAEENDILGRFINAEYTEEAYEGQTALNIAIERRQGDIAALLIAAGA 239
Query: 227 DVQAAAHGDFFKKTKGRPGFYFGELPLSLAACTNQLGIVKFLLQNSWQTADISARDSVGN 286
DV A A G FF GFYFGE PL+LAACTNQ IV+ L+++ + DI++RDS GN
Sbjct: 240 DVNAHAKGAFFNPKYQHEGFYFGETPLALAACTNQPEIVQLLMEH--EQTDITSRDSRGN 297
Query: 287 TVLHALVEVADNTADNTKFVTSMYNEILMLGAKLHPTLKLEELTNKKGMTPLALAAGTGK 346
+LHALV VA++ FV MY+ IL+ +LE N G+TPL LAA GK
Sbjct: 298 NILHALVTVAEDFKTQNDFVKRMYDMILLRSGNW----ELETTRNNDGLTPLQLAAKMGK 353
Query: 347 IGVLAYILQREIQEPECRHLSRKFTEWAYGPVHSSLYDLSCIDTCEKNSVLEVIAYSSSE 406
+L YIL REI+E R LSRKFT+WAYGPV SSLYDL+ +DT NSVLE+ Y+++
Sbjct: 354 AEILKYILSREIKEKRLRSLSRKFTDWAYGPVSSSLYDLTNVDTTTDNSVLEITVYNTN- 412
Query: 407 TPNRHDMLLVEPLNRLLQDKWDRFVKRIFYFNFLVYCLYMIIFTMAAYYRP--VDGLP-P 463
NRH+ML +EPL+ LL KW +F K +F+ +F Y Y I T+ +YYRP + +P P
Sbjct: 413 IDNRHEMLTLEPLHTLLHMKWKKFAKHMFFLSFCFYFFYNITLTLVSYYRPREEEAIPHP 472
Query: 464 FKMEKTGDYFRVTGEILSVLGGVYFFFR-GIQYFLQRRPSMKTLFVDSYSEMLFFLQSLF 522
+ + ++ G + ++ + + GI FL R ++++ D++ +FF+Q++
Sbjct: 473 LALTHKMGWLQLLGRMFVLIWAMCISVKEGIAIFLLRPSDLQSILSDAWFHFVFFIQAVL 532
Query: 523 MLATVVLYFSHLKEYVASMVFSLALGWTNMLYYTRGFQQMGIYAVMIEKMILRDLCRFMF 582
++ +V LY KEY+A +V ++ALGW NMLYYTRGFQ MG+Y+VMI+K+IL D+ +F+F
Sbjct: 533 VILSVFLYLFAYKEYLACLVLAMALGWANMLYYTRGFQSMGMYSVMIQKVILHDVLKFLF 592
Query: 583 VYIVFLFGFSTAVVTLIEDGKNDSLPSESTSHRWRGPACRPPDSSYNSLYSTCLELFKFT 642
VYIVFL GF A+ +LIE D+ SSY S LELFK T
Sbjct: 593 VYIVFLLGFGVALASLIEKCPKDNKDC----------------SSYGSFSDAVLELFKLT 636
Query: 643 IGMGDLEFTENYDFKAVFIILLLAYVILTYILLLNMLIALMGETVNKIAQESKNIWKLQR 702
IG+GDL +N + +F+ LL+ YVILT++LLLNMLIALMGETV +++ES+ IW+LQR
Sbjct: 637 IGLGDLNIQQNSKYPILFLFLLITYVILTFVLLLNMLIALMGETVENVSKESERIWRLQR 696
Query: 703 AITILDTEKSFLKCMRKAFRSGKLLQVGYTPDGKDDYRWCFRVDEVNWTTWNTNVGIINE 762
A TIL+ EK + +R FR G+L +V +DD+R C R++EV WT W T+V +NE
Sbjct: 697 ARTILEFEKMLPEWLRSRFRMGELCKV-----AEDDFRLCLRINEVKWTEWKTHVSFLNE 751
Query: 763 DPG 765
DPG
Sbjct: 752 DPG 754
>gi|22547180 transient receptor potential cation channel, subfamily
V, member 4 isoform b [Homo sapiens]
Length = 811
Score = 372 bits (954), Expect = e-102
Identities = 214/586 (36%), Positives = 336/586 (57%), Gaps = 69/586 (11%)
Query: 286 NTVLHALVEVADNTADNTKFVTSMYNEI-----------------------LMLGAKLHP 322
N + L+++A+ T + +F+ S + +I + GA +H
Sbjct: 207 NDTIPVLLDIAERTGNMREFINSPFRDIYYRGQTALHIAIERRCKHYVELLVAQGADVHA 266
Query: 323 TLKLEELTNKK-------GMTPLALAAGTGKIGVLAYILQREIQEPECRHLSRKFTEWAY 375
+ K G PL+LAA T + ++ Y+ + ++ + R + +
Sbjct: 267 QARGRFFQPKDEGGYFYFGELPLSLAACTNQPHIVNYLTENPHKKADMRRQDSRGNTVLH 326
Query: 376 GPVH------------SSLYDLSCIDTCE--KNSVLEVIAYSSSETP-----------NR 410
V + +YDL + +S LE + + +P NR
Sbjct: 327 ALVAIADNTRENTKFVTKMYDLLLLKCARLFPDSNLEAVLNNDGLSPLMMAAKTGKIGNR 386
Query: 411 HDMLLVEPLNRLLQDKWDRFVKRIFYFNFLVYCLYMIIFTMAAYYRPVDGLPPFKMEKTG 470
H+ML VEP+N LL+DKW +F FY N + Y M+IFT+ AYY+P++G PP+ T
Sbjct: 387 HEMLAVEPINELLRDKWRKFGAVSFYINVVSYLCAMVIFTLTAYYQPLEGTPPYPYRTTV 446
Query: 471 DYFRVTGEILSVLGGVYFFFRGIQ-YFLQRRPSMKTLFVDSYSEMLFFLQSLFMLATVVL 529
DY R+ GE++++ GV FFF I+ F+++ P + +LF+D ++L+F+ S+ ++ + L
Sbjct: 447 DYLRLAGEVITLFTGVLFFFTNIKDLFMKKCPGVNSLFIDGSFQLLYFIYSVLVIVSAAL 506
Query: 530 YFSHLKEYVASMVFSLALGWTNMLYYTRGFQQMGIYAVMIEKMILRDLCRFMFVYIVFLF 589
Y + ++ Y+A MVF+L LGW N LY+TRG + G Y++MI+K++ +DL RF+ VY++F+
Sbjct: 507 YLAGIEAYLAVMVFALVLGWMNALYFTRGLKLTGTYSIMIQKILFKDLFRFLLVYLLFMI 566
Query: 590 GFSTAVVTLIEDGKNDSLPSESTSHRW--RGPACRPPDSSYNSLYSTCLELFKFTIGMGD 647
G+++A+V+L+ N + +E ++ P+CR ++ L L+LFK TIGMGD
Sbjct: 567 GYASALVSLLNPCANMKVCNEDQTNCTVPTYPSCRDSETFSTFL----LDLFKLTIGMGD 622
Query: 648 LEFTENYDFKAVFIILLLAYVILTYILLLNMLIALMGETVNKIAQESKNIWKLQRAITIL 707
LE + + VFIILL+ Y+ILT++LLLNMLIALMGETV ++++ESK+IWKLQ A TIL
Sbjct: 623 LEMLSSTKYPVVFIILLVTYIILTFVLLLNMLIALMGETVGQVSKESKHIWKLQWATTIL 682
Query: 708 DTEKSFLKCMRKAFRSGKLLQVGYTPDGKDDYRWCFRVDEVNWTTWNTNVGIINEDPGNC 767
D E+SF +RKAFRSG+++ VG + DG D RWCFRVDEVNW+ WN N+GIINEDPG
Sbjct: 683 DIERSFPVFLRKAFRSGEMVTVGKSSDGTPDRRWCFRVDEVNWSHWNQNLGIINEDPGKN 742
Query: 768 EGVKRTLSFSLRSSRVSGRHWKNFALVPLLREASARDRQSAQPEEV 813
E + FS R+ W ++VP + E + +++ P+EV
Sbjct: 743 E-TYQYYGFSHTVGRLRRDRWS--SVVPRVVELN----KNSNPDEV 781
Score = 256 bits (653), Expect = 8e-68
Identities = 137/261 (52%), Positives = 179/261 (68%)
Query: 110 LRLYDRRSIFEAVAQNNCQDLESLLLFLQKSKKHLTDNEFKDPETGKTCLLKAMLNLHDG 169
L++++R +F+ V++ + DL+ LL FL KK LTD EF++P TGKTCL KA+LNL +G
Sbjct: 146 LKVFNRPILFDIVSRGSTADLDGLLPFLLTHKKRLTDEEFREPSTGKTCLPKALLNLSNG 205
Query: 170 QNTTIPLLLEIARQTDSLKELVNASYTDSYYKGQTALHIAIERRNMALVTLLVENGADVQ 229
+N TIP+LL+IA +T +++E +N+ + D YY+GQTALHIAIERR V LLV GADV
Sbjct: 206 RNDTIPVLLDIAERTGNMREFINSPFRDIYYRGQTALHIAIERRCKHYVELLVAQGADVH 265
Query: 230 AAAHGDFFKKTKGRPGFYFGELPLSLAACTNQLGIVKFLLQNSWQTADISARDSVGNTVL 289
A A G FF+ FYFGELPLSLAACTNQ IV +L +N + AD+ +DS GNTVL
Sbjct: 266 AQARGRFFQPKDEGGYFYFGELPLSLAACTNQPHIVNYLTENPHKKADMRRQDSRGNTVL 325
Query: 290 HALVEVADNTADNTKFVTSMYNEILMLGAKLHPTLKLEELTNKKGMTPLALAAGTGKIGV 349
HALV +ADNT +NTKFVT MY+ +L+ A+L P LE + N G++PL +AA TGKIG
Sbjct: 326 HALVAIADNTRENTKFVTKMYDLLLLKCARLFPDSNLEAVLNNDGLSPLMMAAKTGKIGN 385
Query: 350 LAYILQREIQEPECRHLSRKF 370
+L E R RKF
Sbjct: 386 RHEMLAVEPINELLRDKWRKF 406
>gi|21314682 transient receptor potential cation channel, subfamily
V, member 6 [Homo sapiens]
Length = 725
Score = 242 bits (618), Expect = 9e-64
Identities = 177/562 (31%), Positives = 274/562 (48%), Gaps = 78/562 (13%)
Query: 185 DSLKELVNASYTDSYYKGQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRP 244
++ ELV T Y+GQTALHIA+ +NM LV L+ A V A A G F+++
Sbjct: 100 EAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNL 159
Query: 245 GFYFGELPLSLAACTNQLGIVKFLLQNSWQTADISARDSVGNTVLHALVEVADNTADNTK 304
YFGE PLS AAC N IV+ L+++ ADI A+DS+GNTVLH L+ N
Sbjct: 160 -IYFGEHPLSFAACVNSEEIVRLLIEHG---ADIRAQDSLGNTVLHILI-----LQPNKT 210
Query: 305 FVTSMYNEILMLGAKLHPTLKLEELTNKKGMTPLALAAGTGKIGVLAYILQREIQEPECR 364
F MYN +L L+ + N +G+TP LA G + +++Q+
Sbjct: 211 FACQMYNLLLSYDRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQK-------- 262
Query: 365 HLSRKFTEWAYGPVHSSLYDLSCIDTC-EKNSVLEVIAYSSSETPNRHDMLLVEPLNRLL 423
RK T+W YGP+ S+LYDL+ ID+ ++ S+LE+I +++ +L P+ L+
Sbjct: 263 ---RKHTQWTYGPLTSTLYDLTEIDSSGDEQSLLELII--TTKKREARQILDQTPVKELV 317
Query: 424 QDKWDRFVKRIFYFNFLVYCLYMIIFTMAAYYRPVDGLPPFKMEKTG------------- 470
KW R+ + F +Y LY+I FTM YRP L P +T
Sbjct: 318 SLKWKRYGRPYFCMLGAIYLLYIICFTMCCIYRP---LKPRTNNRTSPRDNTLLQQKLLQ 374
Query: 471 -------DYFRVTGEILSVLGGVYF--------FFRGIQYFLQRRPSMKTLFVDSYSEML 515
D R+ GE+++V+G + F G+ F + + +L
Sbjct: 375 EAYMTPKDDIRLVGELVTVIGAIIILLVEVPDIFRMGVTRFFGQT------ILGGPFHVL 428
Query: 516 FFLQSLFMLATVVLYFSHLKEYVASMVFSLALGWTNMLYYTRGFQQMGIYAVMIEKMILR 575
+ +L T+V+ V M F+L LGW N++Y+ RGFQ +G + +MI+KMI
Sbjct: 429 IITYAFMVLVTMVMRLISASGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQKMIFG 488
Query: 576 DLCRFMFVYIVFLFGFSTAVVTLIEDGKNDSLPSESTSHRWRGPACRPPDSSYNSLYSTC 635
DL RF ++ V + GF++A + + + E H + P +L+ST
Sbjct: 489 DLMRFCWLMAVVILGFASAFYIIFQ-----TEDPEELGHFYDYPM---------ALFST- 533
Query: 636 LELFKFTIGMGDLEFTENYDFKAVFIILLLAYVILTYILLLNMLIALMGETVNKIAQESK 695
ELF TI G + N D ++ I A+ I+ +L+LN+LIA+MG+T ++A E
Sbjct: 534 FELF-LTIIDGPANY--NVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERD 590
Query: 696 NIWKLQRAITILDTEKSFLKCM 717
+W+ Q T + E+ +C+
Sbjct: 591 ELWRAQIVATTVMLERKLPRCL 612
>gi|17505200 transient receptor potential cation channel, subfamily
V, member 5 [Homo sapiens]
Length = 729
Score = 240 bits (613), Expect = 3e-63
Identities = 173/554 (31%), Positives = 267/554 (48%), Gaps = 62/554 (11%)
Query: 185 DSLKELVNASYTDSYYKGQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRP 244
++ ELV T + GQTALHIA+ +N+ LV L+ A V A A G F+++ R
Sbjct: 100 EAAPELVFEPTTCEAFAGQTALHIAVVNQNVNLVRALLTRRASVSARATGTAFRRSP-RN 158
Query: 245 GFYFGELPLSLAACTNQLGIVKFLLQNSWQTADISARDSVGNTVLHALVEVADNTADNTK 304
YFGE PLS AAC N IV+ L+++ ADI A+DS+GNTVLH L+ N
Sbjct: 159 LIYFGEHPLSFAACVNSEEIVRLLIEHG---ADIRAQDSLGNTVLHILI-----LQPNKT 210
Query: 305 FVTSMYNEILMLGAKLHPTLKLEELTNKKGMTPLALAAGTGKIGVLAYILQREIQEPECR 364
F MYN +L L+ + N +G+TP LA G + +++Q+
Sbjct: 211 FACQMYNLLLSYDGHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQK-------- 262
Query: 365 HLSRKFTEWAYGPVHSSLYDLSCIDTC-EKNSVLEVIAYSSSETPNRHDMLLVEPLNRLL 423
R+ +W YGP+ S LYDL+ ID+ E+ S LE++ SS+ +L P+ L+
Sbjct: 263 ---RRHIQWTYGPLTSILYDLTEIDSWGEELSFLELVV--SSDKREARQILEQTPVKELV 317
Query: 424 QDKWDRFVKRIFYFNFLVYCLYMIIFTMAAYYRPV-----------------DGLPPFKM 466
KW+++ + F +Y LYMI FT YRP+ L
Sbjct: 318 SFKWNKYGRPYFCILAALYLLYMICFTTCCVYRPLKFRGGNRTHSRDITILQQKLLQEAY 377
Query: 467 EKTGDYFRVTGEILSVLGGVYFFFRGIQYFLQRRPSM---KTLFVDSYSEMLFFLQSLFM 523
E D R+ GE++S++G V I + S KT+ + ++ SL +
Sbjct: 378 ETREDIIRLVGELVSIVGAVIILLLEIPDIFRVGASRYFGKTILGGPFHVIIITYASL-V 436
Query: 524 LATVVLYFSHLKEYVASMVFSLALGWTNMLYYTRGFQQMGIYAVMIEKMILRDLCRFMFV 583
L T+V+ ++ V M F+L LGW +++Y+TRGFQ +G + +MI+KMI DL RF ++
Sbjct: 437 LVTMVMRLTNTNGEVVPMSFALVLGWCSVMYFTRGFQMLGPFTIMIQKMIFGDLMRFCWL 496
Query: 584 YIVFLFGFSTAVVTLIEDGKNDSLPSESTSHRWRGPACRPPDSSYNSLYSTCLELFKFTI 643
V + GF++A + + P Y T ELF I
Sbjct: 497 MAVVILGFASAFYIIFQT---------------EDPTSLGQFYDYPMALFTTFELFLTVI 541
Query: 644 GMGDLEFTENYDFKAVFIILLLAYVILTYILLLNMLIALMGETVNKIAQESKNIWKLQRA 703
D + D +F I+ A+ I+ +L+LN+ IA+MG+T ++AQE +W+ Q
Sbjct: 542 ---DAPANYDVDLPFMFSIVNFAFAIIATLLMLNLFIAMMGDTHWRVAQERDELWRAQVV 598
Query: 704 ITILDTEKSFLKCM 717
T + E+ +C+
Sbjct: 599 ATTVMLERKLPRCL 612
>gi|32967601 ankyrin 3 isoform 1 [Homo sapiens]
Length = 4377
Score = 54.3 bits (129), Expect = 5e-07
Identities = 52/164 (31%), Positives = 75/164 (45%), Gaps = 33/164 (20%)
Query: 193 ASYTDSYYKGQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRPGFYFGELP 252
AS + +G+TALH+A +V LV++GA V+A A D + P
Sbjct: 457 ASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDD--------------QTP 502
Query: 253 LSLAACTNQLGIVKFLLQNSWQTADISARDSVGNTVLHALVEVADNTADNTKFVTSMYNE 312
L ++A + IV+ LLQ Q A +A + G T LH + + D F
Sbjct: 503 LHISARLGKADIVQQLLQ---QGASPNAATTSGYTPLH--LSAREGHEDVAAF------- 550
Query: 313 ILMLGAKLHPTLKLEELTNKKGMTPLALAAGTGKIGVLAYILQR 356
+L GA L +T KKG TPL +AA GK+ V +LQ+
Sbjct: 551 LLDHGASL-------SITTKKGFTPLHVAAKYGKLEVANLLLQK 587
Score = 49.7 bits (117), Expect = 1e-05
Identities = 51/169 (30%), Positives = 71/169 (42%), Gaps = 30/169 (17%)
Query: 201 KGQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRPGFYFGELPLSLAACTN 260
KG TALHIA +V +LV NGA+V A + F PL +AA N
Sbjct: 106 KGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGF--------------TPLYMAAQEN 151
Query: 261 QLGIVKFLLQNSWQTADISARDSVGNTVLHALVEVADNTADNTKFVTSMYNEI----LML 316
L +VKFLL N A S G T L ++ + + ++ L +
Sbjct: 152 HLEVVKFLLDNG---ASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHI 208
Query: 317 GAKLHPT----LKLE-----ELTNKKGMTPLALAAGTGKIGVLAYILQR 356
A+ T L L+ ++ +K G TPL +AA G I V +L R
Sbjct: 209 AARKDDTKAAALLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLNR 257
Score = 45.4 bits (106), Expect = 2e-04
Identities = 49/180 (27%), Positives = 69/180 (38%), Gaps = 38/180 (21%)
Query: 202 GQTALHIAIERRNMALVTLLVENGADVQAA--------------AHGDFFKKTKGRPGFY 247
G T LHIA ++ M + T L+E GAD A H D GR
Sbjct: 631 GYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANV 690
Query: 248 -----FGELPLSLAACTNQLGIVKFLLQNSWQTADISARDSVGNTVLHALVEVADNTADN 302
G PL LAA +++ + + L+ Q A + A+ +G T LH
Sbjct: 691 NLSNKSGLTPLHLAAQEDRVNVAEVLVN---QGAHVDAQTKMGYTPLH------------ 735
Query: 303 TKFVTSMYNEILMLGAKLHPTLKLEELTNKKGMTPLALAAGTGKIGVLAYILQREIQEPE 362
V Y I ++ L + K+ T K G TPL AA G ++ +LQ E
Sbjct: 736 ---VGCHYGNIKIVNFLLQHSAKVNAKT-KNGYTPLHQAAQQGHTHIINVLLQNNASPNE 791
Score = 44.3 bits (103), Expect = 5e-04
Identities = 49/178 (27%), Positives = 72/178 (40%), Gaps = 40/178 (22%)
Query: 202 GQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRPGFYFGELPLSLAACTNQ 261
G T LH+A N + LL++ GA AAA G PL +AA NQ
Sbjct: 598 GLTPLHVAAHYDNQKVALLLLDQGASPHAAAKN--------------GYTPLHIAAKKNQ 643
Query: 262 LGIVKFLLQNSWQTADISARDSVGNTVLHALVEVADNTADNTKFVTSMYNEILMLGAKLH 321
+ I LL+ AD +A G +H + + D L+LG +
Sbjct: 644 MDIATTLLEYG---ADANAVTRQGIASVHLAAQ--EGHVDMVS---------LLLGRNAN 689
Query: 322 PTLKLEELTNKKGMTPLALAAGTGKIGVLAYILQREIQEPECRHLSRKFTEWAYGPVH 379
L+NK G+TPL LAA ++ V E+ + H+ + T+ Y P+H
Sbjct: 690 -----VNLSNKSGLTPLHLAAQEDRVNV------AEVLVNQGAHVDAQ-TKMGYTPLH 735
Score = 37.7 bits (86), Expect = 0.045
Identities = 32/99 (32%), Positives = 45/99 (45%), Gaps = 17/99 (17%)
Query: 192 NASYTDSYYKGQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRPGFYFGEL 251
NA+ S G T LH+A + + + +LV GA V A +TK G
Sbjct: 687 NANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDA--------QTK------MGYT 732
Query: 252 PLSLAACTNQLGIVKFLLQNSWQTADISARDSVGNTVLH 290
PL + + IV FLLQ+S A ++A+ G T LH
Sbjct: 733 PLHVGCHYGNIKIVNFLLQHS---AKVNAKTKNGYTPLH 768
Score = 34.7 bits (78), Expect = 0.38
Identities = 57/235 (24%), Positives = 79/235 (33%), Gaps = 51/235 (21%)
Query: 142 KHLTDNEFKDPETGKTCLLKAMLNLHDGQNTTIPLLLE-------------IARQTDSLK 188
K L DN + + L G + + LLLE IA + D K
Sbjct: 157 KFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTK 216
Query: 189 E----LVNASYTDSYYK-GQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGR 243
L N + D K G T LHIA N+ + TLL+ A V A D
Sbjct: 217 AAALLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDI------- 269
Query: 244 PGFYFGELPLSLAACTNQLGIVKFLLQNSWQTADISARDSVGNTVLHALVEVADNTADNT 303
PL +A+ +VK LL A I A+ G T LH
Sbjct: 270 -------TPLHVASKRGNANMVKLLLDRG---AKIDAKTRDGLTPLHCGARSGHEQV--- 316
Query: 304 KFVTSMYNEILMLGAKLHPTLKLEELTNKKGMTPLALAAGTGKIGVLAYILQREI 358
+ ML + P L K G++PL +A + + +LQ +
Sbjct: 317 ---------VEMLLDRAAPILS----KTKNGLSPLHMATQGDHLNCVQLLLQHNV 358
>gi|6912736 transient receptor potential cation channel, subfamily
C, member 5 [Homo sapiens]
Length = 973
Score = 51.2 bits (121), Expect = 4e-06
Identities = 35/145 (24%), Positives = 73/145 (50%), Gaps = 8/145 (5%)
Query: 562 MGIYAVMIEKMILRDLCRFMFVYIVFLFGFSTAVVTLIEDGKNDSLPSESTSHRWRGPAC 621
+G + + +M+L D+ +F+F+Y + L F+ + L + ++ + +G C
Sbjct: 503 LGPLQISLGRMLL-DILKFLFIYCLVLLAFANGLNQLYFYYETRAIDEPNNC---KGIRC 558
Query: 622 RPPDSSYNSLYSTCLELFKFTIGMGDLEFTE---NYDF-KAVFIILLLAYVILTYILLLN 677
++++++L+ T LF G+ +L T ++F + V + Y +++ ++LLN
Sbjct: 559 EKQNNAFSTLFETLQSLFWSVFGLLNLYVTNVKARHEFTEFVGATMFGTYNVISLVVLLN 618
Query: 678 MLIALMGETVNKIAQESKNIWKLQR 702
MLIA+M + IA + WK R
Sbjct: 619 MLIAMMNNSYQLIADHADIEWKFAR 643
>gi|209863032 transient receptor potential cation channel, subfamily
C, member 4 isoform zeta [Homo sapiens]
Length = 804
Score = 50.4 bits (119), Expect = 7e-06
Identities = 36/145 (24%), Positives = 71/145 (48%), Gaps = 11/145 (7%)
Query: 562 MGIYAVMIEKMILRDLCRFMFVYIVFLFGFSTAVVTLIEDGKNDSLPSESTSHRWRGPAC 621
+G + + +M+L D+ +F+F+Y + L F+ + L E+ +G C
Sbjct: 329 LGPLQISLGRMLL-DILKFLFIYCLVLLAFANGLNQLY------FYYEETKGLTCKGIRC 381
Query: 622 RPPDSSYNSLYSTCLELFKFTIGMGDLEFTE---NYDF-KAVFIILLLAYVILTYILLLN 677
++++++L+ T LF G+ +L T ++F + V + Y +++ ++LLN
Sbjct: 382 EKQNNAFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTEFVGATMFGTYNVISLVVLLN 441
Query: 678 MLIALMGETVNKIAQESKNIWKLQR 702
MLIA+M + IA + WK R
Sbjct: 442 MLIAMMNNSYQLIADHADIEWKFAR 466
>gi|209863030 transient receptor potential cation channel, subfamily
C, member 4 isoform delta [Homo sapiens]
Length = 836
Score = 50.4 bits (119), Expect = 7e-06
Identities = 36/145 (24%), Positives = 71/145 (48%), Gaps = 11/145 (7%)
Query: 562 MGIYAVMIEKMILRDLCRFMFVYIVFLFGFSTAVVTLIEDGKNDSLPSESTSHRWRGPAC 621
+G + + +M+L D+ +F+F+Y + L F+ + L E+ +G C
Sbjct: 502 LGPLQISLGRMLL-DILKFLFIYCLVLLAFANGLNQLY------FYYEETKGLTCKGIRC 554
Query: 622 RPPDSSYNSLYSTCLELFKFTIGMGDLEFTE---NYDF-KAVFIILLLAYVILTYILLLN 677
++++++L+ T LF G+ +L T ++F + V + Y +++ ++LLN
Sbjct: 555 EKQNNAFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTEFVGATMFGTYNVISLVVLLN 614
Query: 678 MLIALMGETVNKIAQESKNIWKLQR 702
MLIA+M + IA + WK R
Sbjct: 615 MLIAMMNNSYQLIADHADIEWKFAR 639
>gi|209863026 transient receptor potential cation channel, subfamily
C, member 4 isoform beta [Homo sapiens]
Length = 893
Score = 50.4 bits (119), Expect = 7e-06
Identities = 36/145 (24%), Positives = 71/145 (48%), Gaps = 11/145 (7%)
Query: 562 MGIYAVMIEKMILRDLCRFMFVYIVFLFGFSTAVVTLIEDGKNDSLPSESTSHRWRGPAC 621
+G + + +M+L D+ +F+F+Y + L F+ + L E+ +G C
Sbjct: 502 LGPLQISLGRMLL-DILKFLFIYCLVLLAFANGLNQLY------FYYEETKGLTCKGIRC 554
Query: 622 RPPDSSYNSLYSTCLELFKFTIGMGDLEFTE---NYDF-KAVFIILLLAYVILTYILLLN 677
++++++L+ T LF G+ +L T ++F + V + Y +++ ++LLN
Sbjct: 555 EKQNNAFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTEFVGATMFGTYNVISLVVLLN 614
Query: 678 MLIALMGETVNKIAQESKNIWKLQR 702
MLIA+M + IA + WK R
Sbjct: 615 MLIAMMNNSYQLIADHADIEWKFAR 639
>gi|209863024 transient receptor potential cation channel, subfamily
C, member 4 isoform epsilon [Homo sapiens]
Length = 982
Score = 50.4 bits (119), Expect = 7e-06
Identities = 36/145 (24%), Positives = 71/145 (48%), Gaps = 11/145 (7%)
Query: 562 MGIYAVMIEKMILRDLCRFMFVYIVFLFGFSTAVVTLIEDGKNDSLPSESTSHRWRGPAC 621
+G + + +M+L D+ +F+F+Y + L F+ + L E+ +G C
Sbjct: 502 LGPLQISLGRMLL-DILKFLFIYCLVLLAFANGLNQLY------FYYEETKGLTCKGIRC 554
Query: 622 RPPDSSYNSLYSTCLELFKFTIGMGDLEFTE---NYDF-KAVFIILLLAYVILTYILLLN 677
++++++L+ T LF G+ +L T ++F + V + Y +++ ++LLN
Sbjct: 555 EKQNNAFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTEFVGATMFGTYNVISLVVLLN 614
Query: 678 MLIALMGETVNKIAQESKNIWKLQR 702
MLIA+M + IA + WK R
Sbjct: 615 MLIAMMNNSYQLIADHADIEWKFAR 639
>gi|7706747 transient receptor potential cation channel, subfamily
C, member 4 isoform alpha [Homo sapiens]
Length = 977
Score = 50.4 bits (119), Expect = 7e-06
Identities = 36/145 (24%), Positives = 71/145 (48%), Gaps = 11/145 (7%)
Query: 562 MGIYAVMIEKMILRDLCRFMFVYIVFLFGFSTAVVTLIEDGKNDSLPSESTSHRWRGPAC 621
+G + + +M+L D+ +F+F+Y + L F+ + L E+ +G C
Sbjct: 502 LGPLQISLGRMLL-DILKFLFIYCLVLLAFANGLNQLY------FYYEETKGLTCKGIRC 554
Query: 622 RPPDSSYNSLYSTCLELFKFTIGMGDLEFTE---NYDF-KAVFIILLLAYVILTYILLLN 677
++++++L+ T LF G+ +L T ++F + V + Y +++ ++LLN
Sbjct: 555 EKQNNAFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTEFVGATMFGTYNVISLVVLLN 614
Query: 678 MLIALMGETVNKIAQESKNIWKLQR 702
MLIA+M + IA + WK R
Sbjct: 615 MLIAMMNNSYQLIADHADIEWKFAR 639
>gi|116063534 ankyrin repeat domain 27 (VPS9 domain) [Homo sapiens]
Length = 1050
Score = 50.4 bits (119), Expect = 7e-06
Identities = 81/327 (24%), Positives = 120/327 (36%), Gaps = 61/327 (18%)
Query: 130 LESLLLFLQKSKKHLTDNEFKDPETGKTCLLKAMLNLHDGQNTTIPLLLEIARQTDSLKE 189
L+ + L + TD FK +G ++ +L+ D T+ + D ++
Sbjct: 383 LKQRMSLLSQMTSSPTDCLFKHIASGNQKEVERLLSQEDHDKDTVQKMCHPLCFCDDCEK 442
Query: 190 LVNASYTDSYY--------KGQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTK 241
LV+ D +G T LH+A +L+ LLV GA V A
Sbjct: 443 LVSGRLNDPSVVTPFSRDDRGHTPLHVAAVCGQASLIDLLVSKGAMVNATD--------- 493
Query: 242 GRPGFYFGELPLSLAACTNQLGIVKFLLQNSWQTADISARDSVGNTVLHALVEVADNTAD 301
Y G PL LA C V LL + +A++ +D+ GNT LH D
Sbjct: 494 -----YHGATPLHLA-CQKGYQSVTLLLLHYKASAEV--QDNNGNTPLHLACTYGHE--D 543
Query: 302 NTKFVTSMYNEILMLGAKLHPTLKLEELTNKKGMTPLALAAGTGKIGVLAYILQR----E 357
K + E L ++ N+KG TPL +AA G GV+ +LQ E
Sbjct: 544 CVKALVYYDVESCRL-----------DIGNEKGDTPLHIAARWGYQGVIETLLQNGASTE 592
Query: 358 IQE------------------PECRHLS-RKFTEWAYGPVHSSLYDLSCIDTCEKNSVLE 398
IQ E HLS + + + PV S + I S
Sbjct: 593 IQNRLKETPLKCALNSKILSVMEAYHLSFERRQKSSEAPVQSPQRSVDSISQESSTSSFS 652
Query: 399 VIAYSSSETPNRHDMLLVEPLNRLLQD 425
++ SS + + D VE L R + D
Sbjct: 653 SMSASSRQEETKKDYREVEKLLRAVAD 679
Score = 31.6 bits (70), Expect = 3.2
Identities = 17/37 (45%), Positives = 24/37 (64%)
Query: 193 ASYTDSYYKGQTALHIAIERRNMALVTLLVENGADVQ 229
AS S KG TALH A+ +++ +V LL+ +GA VQ
Sbjct: 834 ASINASNNKGNTALHEAVIEKHVFVVELLLLHGASVQ 870
>gi|116534990 ankyrin-like protein 1 [Homo sapiens]
Length = 1119
Score = 48.1 bits (113), Expect = 3e-05
Identities = 69/318 (21%), Positives = 128/318 (40%), Gaps = 70/318 (22%)
Query: 409 NRHDMLLVEPLNRLLQDKWDRFVKRIFYFNFLVYCLYMIIFTMAAYYRPVDGLPPFKMEK 468
NR ++L L KW + R N YCL +I T+ V+ P
Sbjct: 693 NRIELLNHPVCKEYLLMKWLAYGFRAHMMNLGSYCLGLIPMTILV----VNIKPGMAFNS 748
Query: 469 TG----------------DYFRVTGEILSVLGGVYFFFRGIQYFLQRRPSMKTLFVDSYS 512
TG Y T IL L ++ + + Q++ + F+D +
Sbjct: 749 TGIINETSDHSEILDTTNSYLIKTCMILVFLSSIFGYCKEAGQIFQQK---RNYFMDISN 805
Query: 513 EMLFFLQS---LFMLATVVLYFSHLKEYVASMVFSLALGWTNMLYYTRGFQQMGIYAVMI 569
+ + + + +F+L V +HL+ ++ ++ W N L Y + F+ GI+ VM+
Sbjct: 806 VLEWIIYTTGIIFVLPLFVEIPAHLQWQCGAI--AVYFYWMNFLLYLQRFENCGIFIVML 863
Query: 570 EKMILRDLCR--FMFVYIVFLFGFSTAVVTLIEDGKNDSLPSESTSHRWRGPACRPPDSS 627
E +IL+ L R +F++++ FG S ++ ++D P S
Sbjct: 864 E-VILKTLLRSTVVFIFLLLAFGLSFYILLNLQD---------------------PFSSP 901
Query: 628 YNSLYSTCLELFKFTIGMGDLEFTENY---------DFKAVFIILLLAYVILTYILLLNM 678
S+ T F++ +GD+ + E++ + L+++ I I+L+N+
Sbjct: 902 LLSIIQT------FSMMLGDINYRESFLEPYLRNELAHPVLSFAQLVSFTIFVPIVLMNL 955
Query: 679 LIALMGETVNKIAQESKN 696
LI L V IA+ K+
Sbjct: 956 LIGL---AVGDIAEVQKH 970
Score = 30.0 bits (66), Expect = 9.3
Identities = 33/136 (24%), Positives = 57/136 (41%), Gaps = 25/136 (18%)
Query: 248 FGELPLSLAACTNQLGIVKFLLQNSWQTADISARDSVGNTVLHALVEVADNTADNTKFVT 307
+G PL A NQ+ VKFLL A ++ N + A + +A V
Sbjct: 97 YGNTPLHCAVEKNQIESVKFLLSR-------GANPNLRNFNMMAPLHIA---------VQ 140
Query: 308 SMYNEILMLGAKLHPTLKLEELTNKKGMTPLALAAGTGKIGVLAYILQREIQEPECRHLS 367
M NE++ + + H T+ + L + G T + +A T L +L++ + C
Sbjct: 141 GMNNEVMKVLLE-HRTIDV-NLEGENGNTAVIIACTTNNSEALQILLKKGAK--PC---- 192
Query: 368 RKFTEWAYGPVHSSLY 383
K +W P+H + +
Sbjct: 193 -KSNKWGCFPIHQAAF 207
>gi|20270347 ankyrin repeat domain 54 [Homo sapiens]
Length = 300
Score = 47.8 bits (112), Expect = 4e-05
Identities = 34/90 (37%), Positives = 44/90 (48%), Gaps = 17/90 (18%)
Query: 201 KGQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRPGFYFGELPLSLAACTN 260
KG+TALH A N +V LL+++GAD R G G PL LAACTN
Sbjct: 142 KGRTALHFASCNGNDQIVQLLLDHGAD------------PNQRDG--LGNTPLHLAACTN 187
Query: 261 QLGIVKFLLQNSWQTADISARDSVGNTVLH 290
+ ++ LL+ A + A D G T LH
Sbjct: 188 HVPVITTLLRGG---ARVDALDRAGRTPLH 214
>gi|188595682 ankyrin 2 isoform 3 [Homo sapiens]
Length = 1863
Score = 47.0 bits (110), Expect = 7e-05
Identities = 46/156 (29%), Positives = 68/156 (43%), Gaps = 33/156 (21%)
Query: 201 KGQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRPGFYFGELPLSLAACTN 260
+G+TALH+A + +V L+ NGA V A A + + PL +A+
Sbjct: 442 RGETALHMAARAGQVEVVRCLLRNGALVDARAREE--------------QTPLHIASRLG 487
Query: 261 QLGIVKFLLQNSWQTADISARDSVGNTVLHALVEVADNTADNTKFVTSMYNEILMLGAKL 320
+ IV+ LLQ+ A A + G T LH + + D + + +L GA
Sbjct: 488 KTEIVQLLLQH---MAHPDAATTNGYTPLH--ISAREGQVD-------VASVLLEAGA-- 533
Query: 321 HPTLKLEELTNKKGMTPLALAAGTGKIGVLAYILQR 356
L KKG TPL +AA G + V +LQR
Sbjct: 534 -----AHSLATKKGFTPLHVAAKYGSLDVAKLLLQR 564
Score = 45.8 bits (107), Expect = 2e-04
Identities = 49/179 (27%), Positives = 72/179 (40%), Gaps = 42/179 (23%)
Query: 201 KGQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRPGFYFGELPLSLAACTN 260
KG TALHIA +V +LV+ GA++ A + F PL +AA N
Sbjct: 75 KGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGF--------------TPLYMAAQEN 120
Query: 261 QLGIVKFLLQNSWQTADISARDSVGNTVLHALVEVADNTA------DNTKFVTSMYNEIL 314
+ +VK+LL+N A+ S G T L ++ N A ++TK + L
Sbjct: 121 HIDVVKYLLENG---ANQSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVRL--PAL 175
Query: 315 MLGAKLHPTLKLEEL-----------------TNKKGMTPLALAAGTGKIGVLAYILQR 356
+ A+ T L T + G TPL +AA G + V +L R
Sbjct: 176 HIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNR 234
Score = 43.9 bits (102), Expect = 6e-04
Identities = 43/148 (29%), Positives = 59/148 (39%), Gaps = 33/148 (22%)
Query: 202 GQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRPGFYFGELPLSLAACTNQ 261
G T LH+A N + LL+E GA A A G PL +AA NQ
Sbjct: 575 GLTPLHVAAHYDNQKVALLLLEKGASPHATAKN--------------GYTPLHIAAKKNQ 620
Query: 262 LGIVKFLLQNSWQTADISARDSVGNTVLHALVEVADNTADNTKFVTSMYNEILMLGAKLH 321
+ I LL +T ++ + G T LH + T M +L GA +H
Sbjct: 621 MQIASTLLNYGAETNIVTKQ---GVTPLHLASQEGH---------TDMVTLLLDKGANIH 668
Query: 322 PTLKLEELTNKKGMTPLALAAGTGKIGV 349
++ K G+T L LAA K+ V
Sbjct: 669 -------MSTKSGLTSLHLAAQEDKVNV 689
Score = 43.1 bits (100), Expect = 0.001
Identities = 48/171 (28%), Positives = 72/171 (42%), Gaps = 34/171 (19%)
Query: 202 GQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRPGFYFGELPLSLAACTNQ 261
G T LHIA ++ + ++ LLV+ GA +QA G P+ +AA
Sbjct: 377 GFTPLHIACKKNRIKVMELLVKYGASIQAITES--------------GLTPIHVAAFMGH 422
Query: 262 LGIVKFLLQNSWQTADISARDSVGNTVLH-----ALVEVADNTADNTKFVTSMYNE---I 313
L IV LLQN A + G T LH VEV N V + E
Sbjct: 423 LNIVLLLLQNG---ASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTP 479
Query: 314 LMLGAKLHPT----LKLEELTN-----KKGMTPLALAAGTGKIGVLAYILQ 355
L + ++L T L L+ + + G TPL ++A G++ V + +L+
Sbjct: 480 LHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLE 530
Score = 38.1 bits (87), Expect = 0.034
Identities = 43/169 (25%), Positives = 67/169 (39%), Gaps = 38/169 (22%)
Query: 201 KGQTALHIAIERRNMALVTLLVENGADVQAAAH-----------------GDFFKKTKGR 243
+G T LH+A + + +VTLL++ GA++ + D K
Sbjct: 640 QGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGAD 699
Query: 244 PGFY--FGELPLSLAACTNQLGIVKFLLQNSWQTADISARDSVGNTVLHALVEVADNTAD 301
+ G PL +A + +V FLL+ Q A+++A+ G T LH +
Sbjct: 700 QDAHTKLGYTPLIVACHYGNVKMVNFLLK---QGANVNAKTKNGYTPLHQAAQQGH---- 752
Query: 302 NTKFVTSMYNEILMLGAKLHPTLKLEELTNKKGMTPLALAAGTGKIGVL 350
T + N +L GAK T G T LA+A G I V+
Sbjct: 753 -----THIINVLLQHGAK-------PNATTANGNTALAIAKRLGYISVV 789
Score = 37.7 bits (86), Expect = 0.045
Identities = 53/214 (24%), Positives = 80/214 (37%), Gaps = 40/214 (18%)
Query: 144 LTDNEFKDPETGKTCLLKAMLNLHDGQNTTIPLLLEIARQTDSLKELVNASYTDSYYKGQ 203
L +N+ K GK L + + LLL+ D +++ T+S G
Sbjct: 161 LLENDTK----GKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTES---GF 213
Query: 204 TALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRPGFYFGELPLSLAACTNQLG 263
T LHIA N+ + TLL+ GA V A G PL +A+
Sbjct: 214 TPLHIAAHYGNVNVATLLLNRGAAVDFTARN--------------GITPLHVASKRGNTN 259
Query: 264 IVKFLLQNSWQTADISARDSVGNTVLHALVEVADNTADNTKFVTSMYNEILMLGAKLHPT 323
+VK LL Q I A+ G T LH + + +L GA L
Sbjct: 260 MVKLLLDRGGQ---IDAKTRDGLTPLHCAARSGHD---------QVVELLLERGAPL--- 304
Query: 324 LKLEELTNKKGMTPLALAAGTGKIGVLAYILQRE 357
K G++PL +AA + + ++LQ +
Sbjct: 305 ----LARTKNGLSPLHMAAQGDHVECVKHLLQHK 334
Score = 37.4 bits (85), Expect = 0.058
Identities = 41/156 (26%), Positives = 68/156 (43%), Gaps = 33/156 (21%)
Query: 202 GQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRPGFYFGELPLSLAACTNQ 261
G ALH+A + ++ LV L+ G+ V +A KK G L +A+ Q
Sbjct: 43 GLNALHLAAKEGHVGLVQELLGRGSSVDSAT-----KK---------GNTALHIASLAGQ 88
Query: 262 LGIVKFLLQNSWQTADISARDSVGNTVLHALVEVADNTADNTKFVTSMYNEILMLGAKLH 321
+VK L++ A+I+A+ G T L+ + +N D K+ +L GA
Sbjct: 89 AEVVKVLVKEG---ANINAQSQNGFTPLYMAAQ--ENHIDVVKY-------LLENGAN-- 134
Query: 322 PTLKLEELTNKKGMTPLALAAGTGKIGVLAYILQRE 357
+ + G TPLA+A G +A +L+ +
Sbjct: 135 -----QSTATEDGFTPLAVALQQGHNQAVAILLEND 165
Score = 33.9 bits (76), Expect = 0.65
Identities = 47/181 (25%), Positives = 66/181 (36%), Gaps = 52/181 (28%)
Query: 202 GQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRPGFYFGELPLSLAACTNQ 261
G T LHI+ + + ++L+E GA AH KK G PL +AA
Sbjct: 509 GYTPLHISAREGQVDVASVLLEAGA-----AHSLATKK---------GFTPLHVAAKYGS 554
Query: 262 LGIVKFLLQNSWQTADISARDSVGNTVLHALVEVADNTADNTKFVTSMYNEILMLGAKLH 321
L + K LLQ +A DS G L L A DN K + + GA H
Sbjct: 555 LDVAKLLLQRR------AAADSAGKNGLTPLHVAAHY--DNQKVALLLLEK----GASPH 602
Query: 322 PTLKL--------------------------EELTNKKGMTPLALAAGTGKIGVLAYILQ 355
T K + K+G+TPL LA+ G ++ +L
Sbjct: 603 ATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLD 662
Query: 356 R 356
+
Sbjct: 663 K 663
Score = 32.0 bits (71), Expect = 2.5
Identities = 36/152 (23%), Positives = 64/152 (42%), Gaps = 33/152 (21%)
Query: 204 TALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRPGFYFGELPLSLAACTNQLG 263
TALH+A + + LL++ A+ A A F PL +A N++
Sbjct: 346 TALHVAAHCGHYRVTKLLLDKRANPNARALNGF--------------TPLHIACKKNRIK 391
Query: 264 IVKFLLQNSWQTADISARDSVGNTVLHALVEVADNTADNTKFVTSMYNEILMLGAKLHPT 323
+++ L++ A I A G T +H F+ + +L+L P
Sbjct: 392 VMELLVKYG---ASIQAITESGLTPIHV-----------AAFMGHLNIVLLLLQNGASP- 436
Query: 324 LKLEELTNKKGMTPLALAAGTGKIGVLAYILQ 355
++TN +G T L +AA G++ V+ +L+
Sbjct: 437 ----DVTNIRGETALHMAARAGQVEVVRCLLR 464
>gi|52426737 ankyrin 2 isoform 2 [Homo sapiens]
Length = 1872
Score = 47.0 bits (110), Expect = 7e-05
Identities = 46/156 (29%), Positives = 68/156 (43%), Gaps = 33/156 (21%)
Query: 201 KGQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRPGFYFGELPLSLAACTN 260
+G+TALH+A + +V L+ NGA V A A + + PL +A+
Sbjct: 463 RGETALHMAARAGQVEVVRCLLRNGALVDARAREE--------------QTPLHIASRLG 508
Query: 261 QLGIVKFLLQNSWQTADISARDSVGNTVLHALVEVADNTADNTKFVTSMYNEILMLGAKL 320
+ IV+ LLQ+ A A + G T LH + + D + + +L GA
Sbjct: 509 KTEIVQLLLQH---MAHPDAATTNGYTPLH--ISAREGQVD-------VASVLLEAGA-- 554
Query: 321 HPTLKLEELTNKKGMTPLALAAGTGKIGVLAYILQR 356
L KKG TPL +AA G + V +LQR
Sbjct: 555 -----AHSLATKKGFTPLHVAAKYGSLDVAKLLLQR 585
Score = 45.8 bits (107), Expect = 2e-04
Identities = 49/179 (27%), Positives = 72/179 (40%), Gaps = 42/179 (23%)
Query: 201 KGQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRPGFYFGELPLSLAACTN 260
KG TALHIA +V +LV+ GA++ A + F PL +AA N
Sbjct: 96 KGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGF--------------TPLYMAAQEN 141
Query: 261 QLGIVKFLLQNSWQTADISARDSVGNTVLHALVEVADNTA------DNTKFVTSMYNEIL 314
+ +VK+LL+N A+ S G T L ++ N A ++TK + L
Sbjct: 142 HIDVVKYLLENG---ANQSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVRL--PAL 196
Query: 315 MLGAKLHPTLKLEEL-----------------TNKKGMTPLALAAGTGKIGVLAYILQR 356
+ A+ T L T + G TPL +AA G + V +L R
Sbjct: 197 HIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNR 255
Score = 43.9 bits (102), Expect = 6e-04
Identities = 43/148 (29%), Positives = 59/148 (39%), Gaps = 33/148 (22%)
Query: 202 GQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRPGFYFGELPLSLAACTNQ 261
G T LH+A N + LL+E GA A A G PL +AA NQ
Sbjct: 596 GLTPLHVAAHYDNQKVALLLLEKGASPHATAKN--------------GYTPLHIAAKKNQ 641
Query: 262 LGIVKFLLQNSWQTADISARDSVGNTVLHALVEVADNTADNTKFVTSMYNEILMLGAKLH 321
+ I LL +T ++ + G T LH + T M +L GA +H
Sbjct: 642 MQIASTLLNYGAETNIVTKQ---GVTPLHLASQEGH---------TDMVTLLLDKGANIH 689
Query: 322 PTLKLEELTNKKGMTPLALAAGTGKIGV 349
++ K G+T L LAA K+ V
Sbjct: 690 -------MSTKSGLTSLHLAAQEDKVNV 710
Score = 43.1 bits (100), Expect = 0.001
Identities = 48/171 (28%), Positives = 72/171 (42%), Gaps = 34/171 (19%)
Query: 202 GQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRPGFYFGELPLSLAACTNQ 261
G T LHIA ++ + ++ LLV+ GA +QA G P+ +AA
Sbjct: 398 GFTPLHIACKKNRIKVMELLVKYGASIQAITES--------------GLTPIHVAAFMGH 443
Query: 262 LGIVKFLLQNSWQTADISARDSVGNTVLH-----ALVEVADNTADNTKFVTSMYNE---I 313
L IV LLQN A + G T LH VEV N V + E
Sbjct: 444 LNIVLLLLQNG---ASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTP 500
Query: 314 LMLGAKLHPT----LKLEELTN-----KKGMTPLALAAGTGKIGVLAYILQ 355
L + ++L T L L+ + + G TPL ++A G++ V + +L+
Sbjct: 501 LHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLE 551
Score = 38.1 bits (87), Expect = 0.034
Identities = 43/169 (25%), Positives = 67/169 (39%), Gaps = 38/169 (22%)
Query: 201 KGQTALHIAIERRNMALVTLLVENGADVQAAAH-----------------GDFFKKTKGR 243
+G T LH+A + + +VTLL++ GA++ + D K
Sbjct: 661 QGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGAD 720
Query: 244 PGFY--FGELPLSLAACTNQLGIVKFLLQNSWQTADISARDSVGNTVLHALVEVADNTAD 301
+ G PL +A + +V FLL+ Q A+++A+ G T LH +
Sbjct: 721 QDAHTKLGYTPLIVACHYGNVKMVNFLLK---QGANVNAKTKNGYTPLHQAAQQGH---- 773
Query: 302 NTKFVTSMYNEILMLGAKLHPTLKLEELTNKKGMTPLALAAGTGKIGVL 350
T + N +L GAK T G T LA+A G I V+
Sbjct: 774 -----THIINVLLQHGAK-------PNATTANGNTALAIAKRLGYISVV 810
Score = 37.7 bits (86), Expect = 0.045
Identities = 53/214 (24%), Positives = 80/214 (37%), Gaps = 40/214 (18%)
Query: 144 LTDNEFKDPETGKTCLLKAMLNLHDGQNTTIPLLLEIARQTDSLKELVNASYTDSYYKGQ 203
L +N+ K GK L + + LLL+ D +++ T+S G
Sbjct: 182 LLENDTK----GKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTES---GF 234
Query: 204 TALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRPGFYFGELPLSLAACTNQLG 263
T LHIA N+ + TLL+ GA V A G PL +A+
Sbjct: 235 TPLHIAAHYGNVNVATLLLNRGAAVDFTARN--------------GITPLHVASKRGNTN 280
Query: 264 IVKFLLQNSWQTADISARDSVGNTVLHALVEVADNTADNTKFVTSMYNEILMLGAKLHPT 323
+VK LL Q I A+ G T LH + + +L GA L
Sbjct: 281 MVKLLLDRGGQ---IDAKTRDGLTPLHCAARSGHD---------QVVELLLERGAPL--- 325
Query: 324 LKLEELTNKKGMTPLALAAGTGKIGVLAYILQRE 357
K G++PL +AA + + ++LQ +
Sbjct: 326 ----LARTKNGLSPLHMAAQGDHVECVKHLLQHK 355
Score = 37.4 bits (85), Expect = 0.058
Identities = 41/156 (26%), Positives = 68/156 (43%), Gaps = 33/156 (21%)
Query: 202 GQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRPGFYFGELPLSLAACTNQ 261
G ALH+A + ++ LV L+ G+ V +A KK G L +A+ Q
Sbjct: 64 GLNALHLAAKEGHVGLVQELLGRGSSVDSAT-----KK---------GNTALHIASLAGQ 109
Query: 262 LGIVKFLLQNSWQTADISARDSVGNTVLHALVEVADNTADNTKFVTSMYNEILMLGAKLH 321
+VK L++ A+I+A+ G T L+ + +N D K+ +L GA
Sbjct: 110 AEVVKVLVKEG---ANINAQSQNGFTPLYMAAQ--ENHIDVVKY-------LLENGAN-- 155
Query: 322 PTLKLEELTNKKGMTPLALAAGTGKIGVLAYILQRE 357
+ + G TPLA+A G +A +L+ +
Sbjct: 156 -----QSTATEDGFTPLAVALQQGHNQAVAILLEND 186
Score = 33.9 bits (76), Expect = 0.65
Identities = 47/181 (25%), Positives = 66/181 (36%), Gaps = 52/181 (28%)
Query: 202 GQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRPGFYFGELPLSLAACTNQ 261
G T LHI+ + + ++L+E GA AH KK G PL +AA
Sbjct: 530 GYTPLHISAREGQVDVASVLLEAGA-----AHSLATKK---------GFTPLHVAAKYGS 575
Query: 262 LGIVKFLLQNSWQTADISARDSVGNTVLHALVEVADNTADNTKFVTSMYNEILMLGAKLH 321
L + K LLQ +A DS G L L A DN K + + GA H
Sbjct: 576 LDVAKLLLQRR------AAADSAGKNGLTPLHVAAHY--DNQKVALLLLEK----GASPH 623
Query: 322 PTLKL--------------------------EELTNKKGMTPLALAAGTGKIGVLAYILQ 355
T K + K+G+TPL LA+ G ++ +L
Sbjct: 624 ATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLD 683
Query: 356 R 356
+
Sbjct: 684 K 684
Score = 32.0 bits (71), Expect = 2.5
Identities = 36/152 (23%), Positives = 64/152 (42%), Gaps = 33/152 (21%)
Query: 204 TALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRPGFYFGELPLSLAACTNQLG 263
TALH+A + + LL++ A+ A A F PL +A N++
Sbjct: 367 TALHVAAHCGHYRVTKLLLDKRANPNARALNGF--------------TPLHIACKKNRIK 412
Query: 264 IVKFLLQNSWQTADISARDSVGNTVLHALVEVADNTADNTKFVTSMYNEILMLGAKLHPT 323
+++ L++ A I A G T +H F+ + +L+L P
Sbjct: 413 VMELLVKYG---ASIQAITESGLTPIHV-----------AAFMGHLNIVLLLLQNGASP- 457
Query: 324 LKLEELTNKKGMTPLALAAGTGKIGVLAYILQ 355
++TN +G T L +AA G++ V+ +L+
Sbjct: 458 ----DVTNIRGETALHMAARAGQVEVVRCLLR 485
>gi|52426735 ankyrin 2 isoform 1 [Homo sapiens]
Length = 3957
Score = 47.0 bits (110), Expect = 7e-05
Identities = 46/156 (29%), Positives = 68/156 (43%), Gaps = 33/156 (21%)
Query: 201 KGQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRPGFYFGELPLSLAACTN 260
+G+TALH+A + +V L+ NGA V A A + + PL +A+
Sbjct: 463 RGETALHMAARAGQVEVVRCLLRNGALVDARAREE--------------QTPLHIASRLG 508
Query: 261 QLGIVKFLLQNSWQTADISARDSVGNTVLHALVEVADNTADNTKFVTSMYNEILMLGAKL 320
+ IV+ LLQ+ A A + G T LH + + D + + +L GA
Sbjct: 509 KTEIVQLLLQH---MAHPDAATTNGYTPLH--ISAREGQVD-------VASVLLEAGA-- 554
Query: 321 HPTLKLEELTNKKGMTPLALAAGTGKIGVLAYILQR 356
L KKG TPL +AA G + V +LQR
Sbjct: 555 -----AHSLATKKGFTPLHVAAKYGSLDVAKLLLQR 585
Score = 45.8 bits (107), Expect = 2e-04
Identities = 49/179 (27%), Positives = 72/179 (40%), Gaps = 42/179 (23%)
Query: 201 KGQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRPGFYFGELPLSLAACTN 260
KG TALHIA +V +LV+ GA++ A + F PL +AA N
Sbjct: 96 KGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGF--------------TPLYMAAQEN 141
Query: 261 QLGIVKFLLQNSWQTADISARDSVGNTVLHALVEVADNTA------DNTKFVTSMYNEIL 314
+ +VK+LL+N A+ S G T L ++ N A ++TK + L
Sbjct: 142 HIDVVKYLLENG---ANQSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVRL--PAL 196
Query: 315 MLGAKLHPTLKLEEL-----------------TNKKGMTPLALAAGTGKIGVLAYILQR 356
+ A+ T L T + G TPL +AA G + V +L R
Sbjct: 197 HIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNR 255
Score = 43.9 bits (102), Expect = 6e-04
Identities = 43/148 (29%), Positives = 59/148 (39%), Gaps = 33/148 (22%)
Query: 202 GQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRPGFYFGELPLSLAACTNQ 261
G T LH+A N + LL+E GA A A G PL +AA NQ
Sbjct: 596 GLTPLHVAAHYDNQKVALLLLEKGASPHATAKN--------------GYTPLHIAAKKNQ 641
Query: 262 LGIVKFLLQNSWQTADISARDSVGNTVLHALVEVADNTADNTKFVTSMYNEILMLGAKLH 321
+ I LL +T ++ + G T LH + T M +L GA +H
Sbjct: 642 MQIASTLLNYGAETNIVTKQ---GVTPLHLASQEGH---------TDMVTLLLDKGANIH 689
Query: 322 PTLKLEELTNKKGMTPLALAAGTGKIGV 349
++ K G+T L LAA K+ V
Sbjct: 690 -------MSTKSGLTSLHLAAQEDKVNV 710
Score = 43.1 bits (100), Expect = 0.001
Identities = 48/171 (28%), Positives = 72/171 (42%), Gaps = 34/171 (19%)
Query: 202 GQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRPGFYFGELPLSLAACTNQ 261
G T LHIA ++ + ++ LLV+ GA +QA G P+ +AA
Sbjct: 398 GFTPLHIACKKNRIKVMELLVKYGASIQAITES--------------GLTPIHVAAFMGH 443
Query: 262 LGIVKFLLQNSWQTADISARDSVGNTVLH-----ALVEVADNTADNTKFVTSMYNE---I 313
L IV LLQN A + G T LH VEV N V + E
Sbjct: 444 LNIVLLLLQNG---ASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTP 500
Query: 314 LMLGAKLHPT----LKLEELTN-----KKGMTPLALAAGTGKIGVLAYILQ 355
L + ++L T L L+ + + G TPL ++A G++ V + +L+
Sbjct: 501 LHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLE 551
Score = 38.1 bits (87), Expect = 0.034
Identities = 43/169 (25%), Positives = 67/169 (39%), Gaps = 38/169 (22%)
Query: 201 KGQTALHIAIERRNMALVTLLVENGADVQAAAH-----------------GDFFKKTKGR 243
+G T LH+A + + +VTLL++ GA++ + D K
Sbjct: 661 QGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGAD 720
Query: 244 PGFY--FGELPLSLAACTNQLGIVKFLLQNSWQTADISARDSVGNTVLHALVEVADNTAD 301
+ G PL +A + +V FLL+ Q A+++A+ G T LH +
Sbjct: 721 QDAHTKLGYTPLIVACHYGNVKMVNFLLK---QGANVNAKTKNGYTPLHQAAQQGH---- 773
Query: 302 NTKFVTSMYNEILMLGAKLHPTLKLEELTNKKGMTPLALAAGTGKIGVL 350
T + N +L GAK T G T LA+A G I V+
Sbjct: 774 -----THIINVLLQHGAK-------PNATTANGNTALAIAKRLGYISVV 810
Score = 37.7 bits (86), Expect = 0.045
Identities = 53/214 (24%), Positives = 80/214 (37%), Gaps = 40/214 (18%)
Query: 144 LTDNEFKDPETGKTCLLKAMLNLHDGQNTTIPLLLEIARQTDSLKELVNASYTDSYYKGQ 203
L +N+ K GK L + + LLL+ D +++ T+S G
Sbjct: 182 LLENDTK----GKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTES---GF 234
Query: 204 TALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRPGFYFGELPLSLAACTNQLG 263
T LHIA N+ + TLL+ GA V A G PL +A+
Sbjct: 235 TPLHIAAHYGNVNVATLLLNRGAAVDFTARN--------------GITPLHVASKRGNTN 280
Query: 264 IVKFLLQNSWQTADISARDSVGNTVLHALVEVADNTADNTKFVTSMYNEILMLGAKLHPT 323
+VK LL Q I A+ G T LH + + +L GA L
Sbjct: 281 MVKLLLDRGGQ---IDAKTRDGLTPLHCAARSGHD---------QVVELLLERGAPL--- 325
Query: 324 LKLEELTNKKGMTPLALAAGTGKIGVLAYILQRE 357
K G++PL +AA + + ++LQ +
Sbjct: 326 ----LARTKNGLSPLHMAAQGDHVECVKHLLQHK 355
Score = 37.4 bits (85), Expect = 0.058
Identities = 41/156 (26%), Positives = 68/156 (43%), Gaps = 33/156 (21%)
Query: 202 GQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRPGFYFGELPLSLAACTNQ 261
G ALH+A + ++ LV L+ G+ V +A KK G L +A+ Q
Sbjct: 64 GLNALHLAAKEGHVGLVQELLGRGSSVDSAT-----KK---------GNTALHIASLAGQ 109
Query: 262 LGIVKFLLQNSWQTADISARDSVGNTVLHALVEVADNTADNTKFVTSMYNEILMLGAKLH 321
+VK L++ A+I+A+ G T L+ + +N D K+ +L GA
Sbjct: 110 AEVVKVLVKEG---ANINAQSQNGFTPLYMAAQ--ENHIDVVKY-------LLENGAN-- 155
Query: 322 PTLKLEELTNKKGMTPLALAAGTGKIGVLAYILQRE 357
+ + G TPLA+A G +A +L+ +
Sbjct: 156 -----QSTATEDGFTPLAVALQQGHNQAVAILLEND 186
Score = 33.9 bits (76), Expect = 0.65
Identities = 47/181 (25%), Positives = 66/181 (36%), Gaps = 52/181 (28%)
Query: 202 GQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRPGFYFGELPLSLAACTNQ 261
G T LHI+ + + ++L+E GA AH KK G PL +AA
Sbjct: 530 GYTPLHISAREGQVDVASVLLEAGA-----AHSLATKK---------GFTPLHVAAKYGS 575
Query: 262 LGIVKFLLQNSWQTADISARDSVGNTVLHALVEVADNTADNTKFVTSMYNEILMLGAKLH 321
L + K LLQ +A DS G L L A DN K + + GA H
Sbjct: 576 LDVAKLLLQRR------AAADSAGKNGLTPLHVAAHY--DNQKVALLLLEK----GASPH 623
Query: 322 PTLKL--------------------------EELTNKKGMTPLALAAGTGKIGVLAYILQ 355
T K + K+G+TPL LA+ G ++ +L
Sbjct: 624 ATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLD 683
Query: 356 R 356
+
Sbjct: 684 K 684
Score = 32.0 bits (71), Expect = 2.5
Identities = 36/152 (23%), Positives = 64/152 (42%), Gaps = 33/152 (21%)
Query: 204 TALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRPGFYFGELPLSLAACTNQLG 263
TALH+A + + LL++ A+ A A F PL +A N++
Sbjct: 367 TALHVAAHCGHYRVTKLLLDKRANPNARALNGF--------------TPLHIACKKNRIK 412
Query: 264 IVKFLLQNSWQTADISARDSVGNTVLHALVEVADNTADNTKFVTSMYNEILMLGAKLHPT 323
+++ L++ A I A G T +H F+ + +L+L P
Sbjct: 413 VMELLVKYG---ASIQAITESGLTPIHV-----------AAFMGHLNIVLLLLQNGASP- 457
Query: 324 LKLEELTNKKGMTPLALAAGTGKIGVLAYILQ 355
++TN +G T L +AA G++ V+ +L+
Sbjct: 458 ----DVTNIRGETALHMAARAGQVEVVRCLLR 485
>gi|4507685 transient receptor potential cation channel, subfamily
C, member 1 [Homo sapiens]
Length = 759
Score = 46.2 bits (108), Expect = 1e-04
Identities = 47/253 (18%), Positives = 106/253 (41%), Gaps = 43/253 (16%)
Query: 479 ILSVLGGVY-----FFFRGIQYFLQRRPSMKTLFVDSYSEMLFFLQSLFMLATVVLYFSH 533
IL ++G ++ ++ G++ FL+ +S +++ F + SL++ + +H
Sbjct: 394 ILWIIGMIWSDIKRLWYEGLEDFLE----------ESRNQLSFVMNSLYLATFALKVVAH 443
Query: 534 LK-----------EYVASMVFSLALGWTNMLYYTRGFQQMGIYAVMIEKMI-----LRDL 577
K + ++V + N+L Y R F +++ I L+D
Sbjct: 444 NKFHDFADRKDWDAFHPTLVAEGLFAFANVLSYLRLFFMYTTSSILGPLQISMGQMLQDF 503
Query: 578 CRFMFVYIVFLFGFSTAVVTLIEDGKNDSLPSESTSHRWRGPAC-RPPDSSYNSLYSTCL 636
+F+ ++++ LF F+ + L + G + G C + + +++S TC
Sbjct: 504 GKFLGMFLLVLFSFTIGLTQLYDKGYTSKEQKDCV-----GIFCEQQSNDTFHSFIGTCF 558
Query: 637 ELFKFTIGMGDLE-FTENYDF-----KAVFIILLLAYVILTYILLLNMLIALMGETVNKI 690
LF + + + F + + V +++ Y ++ I+L +L+A++ ++ I
Sbjct: 559 ALFWYIFSLAHVAIFVTRFSYGEELQSFVGAVIVGTYNVVVVIVLTKLLVAMLHKSFQLI 618
Query: 691 AQESKNIWKLQRA 703
A WK RA
Sbjct: 619 ANHEDKEWKFARA 631
>gi|215598574 ankyrin 1 isoform 9 [Homo sapiens]
Length = 1897
Score = 46.2 bits (108), Expect = 1e-04
Identities = 47/195 (24%), Positives = 76/195 (38%), Gaps = 45/195 (23%)
Query: 202 GQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRPGFYFGELP--------- 252
G T LHIA ++ ++ ++ LL++ GA + A T + G LP
Sbjct: 404 GFTPLHIACKKNHVRVMELLLKTGASIDAVTESGL---TPLHVASFMGHLPIVKNLLQRG 460
Query: 253 -------------LSLAACTNQLGIVKFLLQNSWQTADISARDSVGNTVLHALVEVA--- 296
L +AA + K+LLQN A ++A+ T LH +
Sbjct: 461 ASPNVSNVKVETPLHMAARAGHTEVAKYLLQNK---AKVNAKAKDDQTPLHCAARIGHTN 517
Query: 297 ------DNTADNTKFVTSMYNEILMLGAKLHPTLKLEELTN--------KKGMTPLALAA 342
+N A+ T+ + + + + H L L KKG TPL +AA
Sbjct: 518 MVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAA 577
Query: 343 GTGKIGVLAYILQRE 357
GK+ V +L+R+
Sbjct: 578 KYGKVRVAELLLERD 592
Score = 42.4 bits (98), Expect = 0.002
Identities = 44/166 (26%), Positives = 63/166 (37%), Gaps = 24/166 (14%)
Query: 201 KGQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRPGFYFGELPLSLAACTN 260
KG TALHIA +V LV GA+V A + F PL +AA N
Sbjct: 110 KGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGF--------------TPLYMAAQEN 155
Query: 261 QLGIVKFLLQN----------SWQTADISARDSVGNTVLHALVEVADNTADNTKFVTSMY 310
L +VKFLL+N + ++ + N V H + +
Sbjct: 156 HLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLINYGTKGKVRLPALHIAAR 215
Query: 311 NEILMLGAKLHPTLKLEELTNKKGMTPLALAAGTGKIGVLAYILQR 356
N+ A L ++ +K G TPL +AA + V +L R
Sbjct: 216 NDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNR 261
Score = 41.6 bits (96), Expect = 0.003
Identities = 49/186 (26%), Positives = 75/186 (40%), Gaps = 44/186 (23%)
Query: 193 ASYTDSYYKGQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRPGFYFGELP 252
AS S K +T LH+A + + L++N A V A A D + P
Sbjct: 461 ASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDD--------------QTP 506
Query: 253 LSLAACTNQLGIVKFLLQNSWQTADISARDSVGNTVLH------------ALVEVADNTA 300
L AA +VK LL+N+ A+ + + G+T LH AL+E + A
Sbjct: 507 LHCAARIGHTNMVKLLLENN---ANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQA 563
Query: 301 DNTK------FVTSMYNEI----LMLGAKLHPTLKLEELTNKKGMTPLALAAGTGKIGVL 350
TK V + Y ++ L+L HP K G+TPL +A + ++
Sbjct: 564 CMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNA-----AGKNGLTPLHVAVHHNNLDIV 618
Query: 351 AYILQR 356
+L R
Sbjct: 619 KLLLPR 624
Score = 41.6 bits (96), Expect = 0.003
Identities = 43/198 (21%), Positives = 82/198 (41%), Gaps = 43/198 (21%)
Query: 202 GQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRPGFYFGELPLSLAACTNQ 261
G T LH+A+ N+ +V LL+ G + A + G PL +AA NQ
Sbjct: 602 GLTPLHVAVHHNNLDIVKLLLPRGGSPHSPA--------------WNGYTPLHIAAKQNQ 647
Query: 262 LGIVKFLLQNSWQT----------ADISARDSVGNTVLHALVEVADNTADNTKFVTSMYN 311
+ + + LLQ ++A++ V L + A+ N +T ++
Sbjct: 648 VEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLH- 706
Query: 312 EILMLGAKLHPTLK--------LEELTNKKGMTPLALAAGTGKIGVLAYILQREIQEPEC 363
++ + H + + + T + G TPL +A+ G I ++ ++LQ +
Sbjct: 707 ---LVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQAD---- 759
Query: 364 RHLSRKFTEWAYGPVHSS 381
++ K T+ Y P+H +
Sbjct: 760 --VNAK-TKLGYSPLHQA 774
Score = 38.9 bits (89), Expect = 0.020
Identities = 44/193 (22%), Positives = 79/193 (40%), Gaps = 28/193 (14%)
Query: 180 IARQTDSLKELVN--ASYTDSYYKGQTALHIAIERRNMALVTLLVENGADVQAAAHGDFF 237
+A Q + ++ELVN A+ KG T L++A + ++ +V L+ENGA+ A F
Sbjct: 120 LAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGF- 178
Query: 238 KKTKGRPGFYFGELPLSLAACTNQLGIVKFLLQNSWQ------TADISARDSVGNTVLHA 291
PL++A +V L+ + I+AR+ T
Sbjct: 179 -------------TPLAVALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVL 225
Query: 292 L-----VEVADNTADNTKFVTSMYNEILMLGAKLHPTLKLEELTNKKGMTPLALAAGTGK 346
L +V T + + Y + + L+ + T + G+TPL +A+ G
Sbjct: 226 LQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASV-NFTPQNGITPLHIASRRGN 284
Query: 347 IGVLAYILQREIQ 359
+ ++ +L R Q
Sbjct: 285 VIMVRLLLDRGAQ 297
Score = 35.0 bits (79), Expect = 0.29
Identities = 33/110 (30%), Positives = 45/110 (40%), Gaps = 19/110 (17%)
Query: 202 GQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRPGFYFGELPLSLAACTNQ 261
G T LH+A N+ LV L+++ ADV A KTK G PL AA
Sbjct: 734 GYTPLHVASHYGNIKLVKFLLQHQADVNA--------KTK------LGYSPLHQAAQQGH 779
Query: 262 LGIVKFLLQNSWQTADISARDSVGNTVLHAL-----VEVADNTADNTKFV 306
IV LL+N ++S+ + + L +V D T FV
Sbjct: 780 TDIVTLLLKNGASPNEVSSDGTTPLAIAKRLGYISVTDVLKVVTDETSFV 829
Score = 33.9 bits (76), Expect = 0.65
Identities = 41/171 (23%), Positives = 73/171 (42%), Gaps = 36/171 (21%)
Query: 204 TALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRPGFYFGELPLSLAACTNQLG 263
T LH A ++ + +L+++GA +QA KTK G P+ +AA + L
Sbjct: 307 TPLHCAARNGHVRISEILLDHGAPIQA--------KTKN------GLSPIHMAAQGDHLD 352
Query: 264 IVKFLLQNSWQTADISARDSVGNTVLH----------ALVEVADNTADNTK--------F 305
V+ LLQ + DI+ T LH A V + N++
Sbjct: 353 CVRLLLQYDAEIDDITLDHL---TPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLH 409
Query: 306 VTSMYNEILMLGAKLHPTLKLEELTNKKGMTPLALAAGTGKIGVLAYILQR 356
+ N + ++ L ++ +T + G+TPL +A+ G + ++ +LQR
Sbjct: 410 IACKKNHVRVMELLLKTGASIDAVT-ESGLTPLHVASFMGHLPIVKNLLQR 459
>gi|70780359 ankyrin 1 isoform 1 [Homo sapiens]
Length = 1881
Score = 46.2 bits (108), Expect = 1e-04
Identities = 47/195 (24%), Positives = 76/195 (38%), Gaps = 45/195 (23%)
Query: 202 GQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRPGFYFGELP--------- 252
G T LHIA ++ ++ ++ LL++ GA + A T + G LP
Sbjct: 371 GFTPLHIACKKNHVRVMELLLKTGASIDAVTESGL---TPLHVASFMGHLPIVKNLLQRG 427
Query: 253 -------------LSLAACTNQLGIVKFLLQNSWQTADISARDSVGNTVLHALVEVA--- 296
L +AA + K+LLQN A ++A+ T LH +
Sbjct: 428 ASPNVSNVKVETPLHMAARAGHTEVAKYLLQNK---AKVNAKAKDDQTPLHCAARIGHTN 484
Query: 297 ------DNTADNTKFVTSMYNEILMLGAKLHPTLKLEELTN--------KKGMTPLALAA 342
+N A+ T+ + + + + H L L KKG TPL +AA
Sbjct: 485 MVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAA 544
Query: 343 GTGKIGVLAYILQRE 357
GK+ V +L+R+
Sbjct: 545 KYGKVRVAELLLERD 559
Score = 42.4 bits (98), Expect = 0.002
Identities = 44/166 (26%), Positives = 63/166 (37%), Gaps = 24/166 (14%)
Query: 201 KGQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRPGFYFGELPLSLAACTN 260
KG TALHIA +V LV GA+V A + F PL +AA N
Sbjct: 77 KGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGF--------------TPLYMAAQEN 122
Query: 261 QLGIVKFLLQN----------SWQTADISARDSVGNTVLHALVEVADNTADNTKFVTSMY 310
L +VKFLL+N + ++ + N V H + +
Sbjct: 123 HLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLINYGTKGKVRLPALHIAAR 182
Query: 311 NEILMLGAKLHPTLKLEELTNKKGMTPLALAAGTGKIGVLAYILQR 356
N+ A L ++ +K G TPL +AA + V +L R
Sbjct: 183 NDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNR 228
Score = 41.6 bits (96), Expect = 0.003
Identities = 49/186 (26%), Positives = 75/186 (40%), Gaps = 44/186 (23%)
Query: 193 ASYTDSYYKGQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRPGFYFGELP 252
AS S K +T LH+A + + L++N A V A A D + P
Sbjct: 428 ASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDD--------------QTP 473
Query: 253 LSLAACTNQLGIVKFLLQNSWQTADISARDSVGNTVLH------------ALVEVADNTA 300
L AA +VK LL+N+ A+ + + G+T LH AL+E + A
Sbjct: 474 LHCAARIGHTNMVKLLLENN---ANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQA 530
Query: 301 DNTK------FVTSMYNEI----LMLGAKLHPTLKLEELTNKKGMTPLALAAGTGKIGVL 350
TK V + Y ++ L+L HP K G+TPL +A + ++
Sbjct: 531 CMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNA-----AGKNGLTPLHVAVHHNNLDIV 585
Query: 351 AYILQR 356
+L R
Sbjct: 586 KLLLPR 591
Score = 41.6 bits (96), Expect = 0.003
Identities = 43/198 (21%), Positives = 82/198 (41%), Gaps = 43/198 (21%)
Query: 202 GQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRPGFYFGELPLSLAACTNQ 261
G T LH+A+ N+ +V LL+ G + A + G PL +AA NQ
Sbjct: 569 GLTPLHVAVHHNNLDIVKLLLPRGGSPHSPA--------------WNGYTPLHIAAKQNQ 614
Query: 262 LGIVKFLLQNSWQT----------ADISARDSVGNTVLHALVEVADNTADNTKFVTSMYN 311
+ + + LLQ ++A++ V L + A+ N +T ++
Sbjct: 615 VEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLH- 673
Query: 312 EILMLGAKLHPTLK--------LEELTNKKGMTPLALAAGTGKIGVLAYILQREIQEPEC 363
++ + H + + + T + G TPL +A+ G I ++ ++LQ +
Sbjct: 674 ---LVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQAD---- 726
Query: 364 RHLSRKFTEWAYGPVHSS 381
++ K T+ Y P+H +
Sbjct: 727 --VNAK-TKLGYSPLHQA 741
Score = 38.9 bits (89), Expect = 0.020
Identities = 44/193 (22%), Positives = 79/193 (40%), Gaps = 28/193 (14%)
Query: 180 IARQTDSLKELVN--ASYTDSYYKGQTALHIAIERRNMALVTLLVENGADVQAAAHGDFF 237
+A Q + ++ELVN A+ KG T L++A + ++ +V L+ENGA+ A F
Sbjct: 87 LAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGF- 145
Query: 238 KKTKGRPGFYFGELPLSLAACTNQLGIVKFLLQNSWQ------TADISARDSVGNTVLHA 291
PL++A +V L+ + I+AR+ T
Sbjct: 146 -------------TPLAVALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVL 192
Query: 292 L-----VEVADNTADNTKFVTSMYNEILMLGAKLHPTLKLEELTNKKGMTPLALAAGTGK 346
L +V T + + Y + + L+ + T + G+TPL +A+ G
Sbjct: 193 LQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASV-NFTPQNGITPLHIASRRGN 251
Query: 347 IGVLAYILQREIQ 359
+ ++ +L R Q
Sbjct: 252 VIMVRLLLDRGAQ 264
Score = 35.0 bits (79), Expect = 0.29
Identities = 33/110 (30%), Positives = 45/110 (40%), Gaps = 19/110 (17%)
Query: 202 GQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRPGFYFGELPLSLAACTNQ 261
G T LH+A N+ LV L+++ ADV A KTK G PL AA
Sbjct: 701 GYTPLHVASHYGNIKLVKFLLQHQADVNA--------KTK------LGYSPLHQAAQQGH 746
Query: 262 LGIVKFLLQNSWQTADISARDSVGNTVLHAL-----VEVADNTADNTKFV 306
IV LL+N ++S+ + + L +V D T FV
Sbjct: 747 TDIVTLLLKNGASPNEVSSDGTTPLAIAKRLGYISVTDVLKVVTDETSFV 796
Score = 33.9 bits (76), Expect = 0.65
Identities = 41/171 (23%), Positives = 73/171 (42%), Gaps = 36/171 (21%)
Query: 204 TALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRPGFYFGELPLSLAACTNQLG 263
T LH A ++ + +L+++GA +QA KTK G P+ +AA + L
Sbjct: 274 TPLHCAARNGHVRISEILLDHGAPIQA--------KTKN------GLSPIHMAAQGDHLD 319
Query: 264 IVKFLLQNSWQTADISARDSVGNTVLH----------ALVEVADNTADNTK--------F 305
V+ LLQ + DI+ T LH A V + N++
Sbjct: 320 CVRLLLQYDAEIDDITLDHL---TPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLH 376
Query: 306 VTSMYNEILMLGAKLHPTLKLEELTNKKGMTPLALAAGTGKIGVLAYILQR 356
+ N + ++ L ++ +T + G+TPL +A+ G + ++ +LQR
Sbjct: 377 IACKKNHVRVMELLLKTGASIDAVT-ESGLTPLHVASFMGHLPIVKNLLQR 426
>gi|70780357 ankyrin 1 isoform 3 [Homo sapiens]
Length = 1880
Score = 46.2 bits (108), Expect = 1e-04
Identities = 47/195 (24%), Positives = 76/195 (38%), Gaps = 45/195 (23%)
Query: 202 GQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRPGFYFGELP--------- 252
G T LHIA ++ ++ ++ LL++ GA + A T + G LP
Sbjct: 371 GFTPLHIACKKNHVRVMELLLKTGASIDAVTESGL---TPLHVASFMGHLPIVKNLLQRG 427
Query: 253 -------------LSLAACTNQLGIVKFLLQNSWQTADISARDSVGNTVLHALVEVA--- 296
L +AA + K+LLQN A ++A+ T LH +
Sbjct: 428 ASPNVSNVKVETPLHMAARAGHTEVAKYLLQNK---AKVNAKAKDDQTPLHCAARIGHTN 484
Query: 297 ------DNTADNTKFVTSMYNEILMLGAKLHPTLKLEELTN--------KKGMTPLALAA 342
+N A+ T+ + + + + H L L KKG TPL +AA
Sbjct: 485 MVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAA 544
Query: 343 GTGKIGVLAYILQRE 357
GK+ V +L+R+
Sbjct: 545 KYGKVRVAELLLERD 559
Score = 42.4 bits (98), Expect = 0.002
Identities = 44/166 (26%), Positives = 63/166 (37%), Gaps = 24/166 (14%)
Query: 201 KGQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRPGFYFGELPLSLAACTN 260
KG TALHIA +V LV GA+V A + F PL +AA N
Sbjct: 77 KGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGF--------------TPLYMAAQEN 122
Query: 261 QLGIVKFLLQN----------SWQTADISARDSVGNTVLHALVEVADNTADNTKFVTSMY 310
L +VKFLL+N + ++ + N V H + +
Sbjct: 123 HLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLINYGTKGKVRLPALHIAAR 182
Query: 311 NEILMLGAKLHPTLKLEELTNKKGMTPLALAAGTGKIGVLAYILQR 356
N+ A L ++ +K G TPL +AA + V +L R
Sbjct: 183 NDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNR 228
Score = 41.6 bits (96), Expect = 0.003
Identities = 49/186 (26%), Positives = 75/186 (40%), Gaps = 44/186 (23%)
Query: 193 ASYTDSYYKGQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRPGFYFGELP 252
AS S K +T LH+A + + L++N A V A A D + P
Sbjct: 428 ASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDD--------------QTP 473
Query: 253 LSLAACTNQLGIVKFLLQNSWQTADISARDSVGNTVLH------------ALVEVADNTA 300
L AA +VK LL+N+ A+ + + G+T LH AL+E + A
Sbjct: 474 LHCAARIGHTNMVKLLLENN---ANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQA 530
Query: 301 DNTK------FVTSMYNEI----LMLGAKLHPTLKLEELTNKKGMTPLALAAGTGKIGVL 350
TK V + Y ++ L+L HP K G+TPL +A + ++
Sbjct: 531 CMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNA-----AGKNGLTPLHVAVHHNNLDIV 585
Query: 351 AYILQR 356
+L R
Sbjct: 586 KLLLPR 591
Score = 41.6 bits (96), Expect = 0.003
Identities = 43/198 (21%), Positives = 82/198 (41%), Gaps = 43/198 (21%)
Query: 202 GQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRPGFYFGELPLSLAACTNQ 261
G T LH+A+ N+ +V LL+ G + A + G PL +AA NQ
Sbjct: 569 GLTPLHVAVHHNNLDIVKLLLPRGGSPHSPA--------------WNGYTPLHIAAKQNQ 614
Query: 262 LGIVKFLLQNSWQT----------ADISARDSVGNTVLHALVEVADNTADNTKFVTSMYN 311
+ + + LLQ ++A++ V L + A+ N +T ++
Sbjct: 615 VEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLH- 673
Query: 312 EILMLGAKLHPTLK--------LEELTNKKGMTPLALAAGTGKIGVLAYILQREIQEPEC 363
++ + H + + + T + G TPL +A+ G I ++ ++LQ +
Sbjct: 674 ---LVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQAD---- 726
Query: 364 RHLSRKFTEWAYGPVHSS 381
++ K T+ Y P+H +
Sbjct: 727 --VNAK-TKLGYSPLHQA 741
Score = 38.9 bits (89), Expect = 0.020
Identities = 44/193 (22%), Positives = 79/193 (40%), Gaps = 28/193 (14%)
Query: 180 IARQTDSLKELVN--ASYTDSYYKGQTALHIAIERRNMALVTLLVENGADVQAAAHGDFF 237
+A Q + ++ELVN A+ KG T L++A + ++ +V L+ENGA+ A F
Sbjct: 87 LAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGF- 145
Query: 238 KKTKGRPGFYFGELPLSLAACTNQLGIVKFLLQNSWQ------TADISARDSVGNTVLHA 291
PL++A +V L+ + I+AR+ T
Sbjct: 146 -------------TPLAVALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVL 192
Query: 292 L-----VEVADNTADNTKFVTSMYNEILMLGAKLHPTLKLEELTNKKGMTPLALAAGTGK 346
L +V T + + Y + + L+ + T + G+TPL +A+ G
Sbjct: 193 LQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASV-NFTPQNGITPLHIASRRGN 251
Query: 347 IGVLAYILQREIQ 359
+ ++ +L R Q
Sbjct: 252 VIMVRLLLDRGAQ 264
Score = 35.0 bits (79), Expect = 0.29
Identities = 33/110 (30%), Positives = 45/110 (40%), Gaps = 19/110 (17%)
Query: 202 GQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRPGFYFGELPLSLAACTNQ 261
G T LH+A N+ LV L+++ ADV A KTK G PL AA
Sbjct: 701 GYTPLHVASHYGNIKLVKFLLQHQADVNA--------KTK------LGYSPLHQAAQQGH 746
Query: 262 LGIVKFLLQNSWQTADISARDSVGNTVLHAL-----VEVADNTADNTKFV 306
IV LL+N ++S+ + + L +V D T FV
Sbjct: 747 TDIVTLLLKNGASPNEVSSDGTTPLAIAKRLGYISVTDVLKVVTDETSFV 796
Score = 33.9 bits (76), Expect = 0.65
Identities = 41/171 (23%), Positives = 73/171 (42%), Gaps = 36/171 (21%)
Query: 204 TALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRPGFYFGELPLSLAACTNQLG 263
T LH A ++ + +L+++GA +QA KTK G P+ +AA + L
Sbjct: 274 TPLHCAARNGHVRISEILLDHGAPIQA--------KTKN------GLSPIHMAAQGDHLD 319
Query: 264 IVKFLLQNSWQTADISARDSVGNTVLH----------ALVEVADNTADNTK--------F 305
V+ LLQ + DI+ T LH A V + N++
Sbjct: 320 CVRLLLQYDAEIDDITLDHL---TPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLH 376
Query: 306 VTSMYNEILMLGAKLHPTLKLEELTNKKGMTPLALAAGTGKIGVLAYILQR 356
+ N + ++ L ++ +T + G+TPL +A+ G + ++ +LQR
Sbjct: 377 IACKKNHVRVMELLLKTGASIDAVT-ESGLTPLHVASFMGHLPIVKNLLQR 426
>gi|70780355 ankyrin 1 isoform 2 [Homo sapiens]
Length = 1719
Score = 46.2 bits (108), Expect = 1e-04
Identities = 47/195 (24%), Positives = 76/195 (38%), Gaps = 45/195 (23%)
Query: 202 GQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRPGFYFGELP--------- 252
G T LHIA ++ ++ ++ LL++ GA + A T + G LP
Sbjct: 371 GFTPLHIACKKNHVRVMELLLKTGASIDAVTESGL---TPLHVASFMGHLPIVKNLLQRG 427
Query: 253 -------------LSLAACTNQLGIVKFLLQNSWQTADISARDSVGNTVLHALVEVA--- 296
L +AA + K+LLQN A ++A+ T LH +
Sbjct: 428 ASPNVSNVKVETPLHMAARAGHTEVAKYLLQNK---AKVNAKAKDDQTPLHCAARIGHTN 484
Query: 297 ------DNTADNTKFVTSMYNEILMLGAKLHPTLKLEELTN--------KKGMTPLALAA 342
+N A+ T+ + + + + H L L KKG TPL +AA
Sbjct: 485 MVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAA 544
Query: 343 GTGKIGVLAYILQRE 357
GK+ V +L+R+
Sbjct: 545 KYGKVRVAELLLERD 559
Score = 42.4 bits (98), Expect = 0.002
Identities = 44/166 (26%), Positives = 63/166 (37%), Gaps = 24/166 (14%)
Query: 201 KGQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRPGFYFGELPLSLAACTN 260
KG TALHIA +V LV GA+V A + F PL +AA N
Sbjct: 77 KGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGF--------------TPLYMAAQEN 122
Query: 261 QLGIVKFLLQN----------SWQTADISARDSVGNTVLHALVEVADNTADNTKFVTSMY 310
L +VKFLL+N + ++ + N V H + +
Sbjct: 123 HLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLINYGTKGKVRLPALHIAAR 182
Query: 311 NEILMLGAKLHPTLKLEELTNKKGMTPLALAAGTGKIGVLAYILQR 356
N+ A L ++ +K G TPL +AA + V +L R
Sbjct: 183 NDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNR 228
Score = 41.6 bits (96), Expect = 0.003
Identities = 49/186 (26%), Positives = 75/186 (40%), Gaps = 44/186 (23%)
Query: 193 ASYTDSYYKGQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRPGFYFGELP 252
AS S K +T LH+A + + L++N A V A A D + P
Sbjct: 428 ASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDD--------------QTP 473
Query: 253 LSLAACTNQLGIVKFLLQNSWQTADISARDSVGNTVLH------------ALVEVADNTA 300
L AA +VK LL+N+ A+ + + G+T LH AL+E + A
Sbjct: 474 LHCAARIGHTNMVKLLLENN---ANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQA 530
Query: 301 DNTK------FVTSMYNEI----LMLGAKLHPTLKLEELTNKKGMTPLALAAGTGKIGVL 350
TK V + Y ++ L+L HP K G+TPL +A + ++
Sbjct: 531 CMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNA-----AGKNGLTPLHVAVHHNNLDIV 585
Query: 351 AYILQR 356
+L R
Sbjct: 586 KLLLPR 591
Score = 41.6 bits (96), Expect = 0.003
Identities = 43/198 (21%), Positives = 82/198 (41%), Gaps = 43/198 (21%)
Query: 202 GQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRPGFYFGELPLSLAACTNQ 261
G T LH+A+ N+ +V LL+ G + A + G PL +AA NQ
Sbjct: 569 GLTPLHVAVHHNNLDIVKLLLPRGGSPHSPA--------------WNGYTPLHIAAKQNQ 614
Query: 262 LGIVKFLLQNSWQT----------ADISARDSVGNTVLHALVEVADNTADNTKFVTSMYN 311
+ + + LLQ ++A++ V L + A+ N +T ++
Sbjct: 615 VEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLH- 673
Query: 312 EILMLGAKLHPTLK--------LEELTNKKGMTPLALAAGTGKIGVLAYILQREIQEPEC 363
++ + H + + + T + G TPL +A+ G I ++ ++LQ +
Sbjct: 674 ---LVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQAD---- 726
Query: 364 RHLSRKFTEWAYGPVHSS 381
++ K T+ Y P+H +
Sbjct: 727 --VNAK-TKLGYSPLHQA 741
Score = 38.9 bits (89), Expect = 0.020
Identities = 44/193 (22%), Positives = 79/193 (40%), Gaps = 28/193 (14%)
Query: 180 IARQTDSLKELVN--ASYTDSYYKGQTALHIAIERRNMALVTLLVENGADVQAAAHGDFF 237
+A Q + ++ELVN A+ KG T L++A + ++ +V L+ENGA+ A F
Sbjct: 87 LAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGF- 145
Query: 238 KKTKGRPGFYFGELPLSLAACTNQLGIVKFLLQNSWQ------TADISARDSVGNTVLHA 291
PL++A +V L+ + I+AR+ T
Sbjct: 146 -------------TPLAVALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVL 192
Query: 292 L-----VEVADNTADNTKFVTSMYNEILMLGAKLHPTLKLEELTNKKGMTPLALAAGTGK 346
L +V T + + Y + + L+ + T + G+TPL +A+ G
Sbjct: 193 LQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASV-NFTPQNGITPLHIASRRGN 251
Query: 347 IGVLAYILQREIQ 359
+ ++ +L R Q
Sbjct: 252 VIMVRLLLDRGAQ 264
Score = 35.0 bits (79), Expect = 0.29
Identities = 33/110 (30%), Positives = 45/110 (40%), Gaps = 19/110 (17%)
Query: 202 GQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRPGFYFGELPLSLAACTNQ 261
G T LH+A N+ LV L+++ ADV A KTK G PL AA
Sbjct: 701 GYTPLHVASHYGNIKLVKFLLQHQADVNA--------KTK------LGYSPLHQAAQQGH 746
Query: 262 LGIVKFLLQNSWQTADISARDSVGNTVLHAL-----VEVADNTADNTKFV 306
IV LL+N ++S+ + + L +V D T FV
Sbjct: 747 TDIVTLLLKNGASPNEVSSDGTTPLAIAKRLGYISVTDVLKVVTDETSFV 796
Score = 33.9 bits (76), Expect = 0.65
Identities = 41/171 (23%), Positives = 73/171 (42%), Gaps = 36/171 (21%)
Query: 204 TALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRPGFYFGELPLSLAACTNQLG 263
T LH A ++ + +L+++GA +QA KTK G P+ +AA + L
Sbjct: 274 TPLHCAARNGHVRISEILLDHGAPIQA--------KTKN------GLSPIHMAAQGDHLD 319
Query: 264 IVKFLLQNSWQTADISARDSVGNTVLH----------ALVEVADNTADNTK--------F 305
V+ LLQ + DI+ T LH A V + N++
Sbjct: 320 CVRLLLQYDAEIDDITLDHL---TPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLH 376
Query: 306 VTSMYNEILMLGAKLHPTLKLEELTNKKGMTPLALAAGTGKIGVLAYILQR 356
+ N + ++ L ++ +T + G+TPL +A+ G + ++ +LQR
Sbjct: 377 IACKKNHVRVMELLLKTGASIDAVT-ESGLTPLHVASFMGHLPIVKNLLQR 426
>gi|70780353 ankyrin 1 isoform 4 [Homo sapiens]
Length = 1856
Score = 46.2 bits (108), Expect = 1e-04
Identities = 47/195 (24%), Positives = 76/195 (38%), Gaps = 45/195 (23%)
Query: 202 GQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRPGFYFGELP--------- 252
G T LHIA ++ ++ ++ LL++ GA + A T + G LP
Sbjct: 371 GFTPLHIACKKNHVRVMELLLKTGASIDAVTESGL---TPLHVASFMGHLPIVKNLLQRG 427
Query: 253 -------------LSLAACTNQLGIVKFLLQNSWQTADISARDSVGNTVLHALVEVA--- 296
L +AA + K+LLQN A ++A+ T LH +
Sbjct: 428 ASPNVSNVKVETPLHMAARAGHTEVAKYLLQNK---AKVNAKAKDDQTPLHCAARIGHTN 484
Query: 297 ------DNTADNTKFVTSMYNEILMLGAKLHPTLKLEELTN--------KKGMTPLALAA 342
+N A+ T+ + + + + H L L KKG TPL +AA
Sbjct: 485 MVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAA 544
Query: 343 GTGKIGVLAYILQRE 357
GK+ V +L+R+
Sbjct: 545 KYGKVRVAELLLERD 559
Score = 42.4 bits (98), Expect = 0.002
Identities = 44/166 (26%), Positives = 63/166 (37%), Gaps = 24/166 (14%)
Query: 201 KGQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRPGFYFGELPLSLAACTN 260
KG TALHIA +V LV GA+V A + F PL +AA N
Sbjct: 77 KGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGF--------------TPLYMAAQEN 122
Query: 261 QLGIVKFLLQN----------SWQTADISARDSVGNTVLHALVEVADNTADNTKFVTSMY 310
L +VKFLL+N + ++ + N V H + +
Sbjct: 123 HLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLINYGTKGKVRLPALHIAAR 182
Query: 311 NEILMLGAKLHPTLKLEELTNKKGMTPLALAAGTGKIGVLAYILQR 356
N+ A L ++ +K G TPL +AA + V +L R
Sbjct: 183 NDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNR 228
Score = 41.6 bits (96), Expect = 0.003
Identities = 49/186 (26%), Positives = 75/186 (40%), Gaps = 44/186 (23%)
Query: 193 ASYTDSYYKGQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRPGFYFGELP 252
AS S K +T LH+A + + L++N A V A A D + P
Sbjct: 428 ASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDD--------------QTP 473
Query: 253 LSLAACTNQLGIVKFLLQNSWQTADISARDSVGNTVLH------------ALVEVADNTA 300
L AA +VK LL+N+ A+ + + G+T LH AL+E + A
Sbjct: 474 LHCAARIGHTNMVKLLLENN---ANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQA 530
Query: 301 DNTK------FVTSMYNEI----LMLGAKLHPTLKLEELTNKKGMTPLALAAGTGKIGVL 350
TK V + Y ++ L+L HP K G+TPL +A + ++
Sbjct: 531 CMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNA-----AGKNGLTPLHVAVHHNNLDIV 585
Query: 351 AYILQR 356
+L R
Sbjct: 586 KLLLPR 591
Score = 41.6 bits (96), Expect = 0.003
Identities = 43/198 (21%), Positives = 82/198 (41%), Gaps = 43/198 (21%)
Query: 202 GQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRPGFYFGELPLSLAACTNQ 261
G T LH+A+ N+ +V LL+ G + A + G PL +AA NQ
Sbjct: 569 GLTPLHVAVHHNNLDIVKLLLPRGGSPHSPA--------------WNGYTPLHIAAKQNQ 614
Query: 262 LGIVKFLLQNSWQT----------ADISARDSVGNTVLHALVEVADNTADNTKFVTSMYN 311
+ + + LLQ ++A++ V L + A+ N +T ++
Sbjct: 615 VEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLH- 673
Query: 312 EILMLGAKLHPTLK--------LEELTNKKGMTPLALAAGTGKIGVLAYILQREIQEPEC 363
++ + H + + + T + G TPL +A+ G I ++ ++LQ +
Sbjct: 674 ---LVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQAD---- 726
Query: 364 RHLSRKFTEWAYGPVHSS 381
++ K T+ Y P+H +
Sbjct: 727 --VNAK-TKLGYSPLHQA 741
Score = 38.9 bits (89), Expect = 0.020
Identities = 44/193 (22%), Positives = 79/193 (40%), Gaps = 28/193 (14%)
Query: 180 IARQTDSLKELVN--ASYTDSYYKGQTALHIAIERRNMALVTLLVENGADVQAAAHGDFF 237
+A Q + ++ELVN A+ KG T L++A + ++ +V L+ENGA+ A F
Sbjct: 87 LAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGF- 145
Query: 238 KKTKGRPGFYFGELPLSLAACTNQLGIVKFLLQNSWQ------TADISARDSVGNTVLHA 291
PL++A +V L+ + I+AR+ T
Sbjct: 146 -------------TPLAVALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVL 192
Query: 292 L-----VEVADNTADNTKFVTSMYNEILMLGAKLHPTLKLEELTNKKGMTPLALAAGTGK 346
L +V T + + Y + + L+ + T + G+TPL +A+ G
Sbjct: 193 LQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASV-NFTPQNGITPLHIASRRGN 251
Query: 347 IGVLAYILQREIQ 359
+ ++ +L R Q
Sbjct: 252 VIMVRLLLDRGAQ 264
Score = 35.0 bits (79), Expect = 0.29
Identities = 33/110 (30%), Positives = 45/110 (40%), Gaps = 19/110 (17%)
Query: 202 GQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRPGFYFGELPLSLAACTNQ 261
G T LH+A N+ LV L+++ ADV A KTK G PL AA
Sbjct: 701 GYTPLHVASHYGNIKLVKFLLQHQADVNA--------KTK------LGYSPLHQAAQQGH 746
Query: 262 LGIVKFLLQNSWQTADISARDSVGNTVLHAL-----VEVADNTADNTKFV 306
IV LL+N ++S+ + + L +V D T FV
Sbjct: 747 TDIVTLLLKNGASPNEVSSDGTTPLAIAKRLGYISVTDVLKVVTDETSFV 796
Score = 33.9 bits (76), Expect = 0.65
Identities = 41/171 (23%), Positives = 73/171 (42%), Gaps = 36/171 (21%)
Query: 204 TALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRPGFYFGELPLSLAACTNQLG 263
T LH A ++ + +L+++GA +QA KTK G P+ +AA + L
Sbjct: 274 TPLHCAARNGHVRISEILLDHGAPIQA--------KTKN------GLSPIHMAAQGDHLD 319
Query: 264 IVKFLLQNSWQTADISARDSVGNTVLH----------ALVEVADNTADNTK--------F 305
V+ LLQ + DI+ T LH A V + N++
Sbjct: 320 CVRLLLQYDAEIDDITLDHL---TPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLH 376
Query: 306 VTSMYNEILMLGAKLHPTLKLEELTNKKGMTPLALAAGTGKIGVLAYILQR 356
+ N + ++ L ++ +T + G+TPL +A+ G + ++ +LQR
Sbjct: 377 IACKKNHVRVMELLLKTGASIDAVT-ESGLTPLHVASFMGHLPIVKNLLQR 426
>gi|209863028 transient receptor potential cation channel, subfamily
C, member 4 isoform gamma [Homo sapiens]
Length = 828
Score = 45.8 bits (107), Expect = 2e-04
Identities = 33/137 (24%), Positives = 69/137 (50%), Gaps = 11/137 (8%)
Query: 562 MGIYAVMIEKMILRDLCRFMFVYIVFLFGFSTAVVTLIEDGKNDSLPSESTSHRWRGPAC 621
+G + + +M+L D+ +F+F+Y + L F+ + L E+ +G C
Sbjct: 502 LGPLQISLGRMLL-DILKFLFIYCLVLLAFANGLNQLY------FYYEETKGLTCKGIRC 554
Query: 622 RPPDSSYNSLYSTCLELFKFTIGMGDLEFTE---NYDF-KAVFIILLLAYVILTYILLLN 677
++++++L+ T LF G+ +L T ++F + V + Y +++ ++LLN
Sbjct: 555 EKQNNAFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTEFVGATMFGTYNVISLVVLLN 614
Query: 678 MLIALMGETVNKIAQES 694
MLIA+M + IA+ +
Sbjct: 615 MLIAMMNNSYQLIARRA 631
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.136 0.409
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,514,703
Number of Sequences: 37866
Number of extensions: 1400277
Number of successful extensions: 5466
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 84
Number of HSP's successfully gapped in prelim test: 163
Number of HSP's that attempted gapping in prelim test: 4589
Number of HSP's gapped (non-prelim): 740
length of query: 839
length of database: 18,247,518
effective HSP length: 111
effective length of query: 728
effective length of database: 14,044,392
effective search space: 10224317376
effective search space used: 10224317376
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.