Guide to the Human Genome
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Search of human proteins with 74275346

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|74275346 adenosylmethionine decarboxylase 1 isoform 1
precursor [Homo sapiens]
         (334 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|74275346 adenosylmethionine decarboxylase 1 isoform 1 precurs...   680   0.0  
gi|74275348 adenosylmethionine decarboxylase 1 isoform 2 [Homo s...   382   e-106
gi|169167822 PREDICTED: similar to hCG17429 [Homo sapiens]            189   3e-48
gi|169167904 PREDICTED: similar to hCG17429 [Homo sapiens]            189   3e-48
gi|239742531 PREDICTED: similar to hCG17429 [Homo sapiens]            189   3e-48
gi|21687001 DNA-damage-inducible transcript 4-like [Homo sapiens]      31   1.4  
gi|120953264 folliculin interacting protein 1 isoform 2 [Homo sa...    29   5.2  
gi|120953291 folliculin interacting protein 1 isoform 1 [Homo sa...    29   5.2  

>gi|74275346 adenosylmethionine decarboxylase 1 isoform 1 precursor
           [Homo sapiens]
          Length = 334

 Score =  680 bits (1755), Expect = 0.0
 Identities = 334/334 (100%), Positives = 334/334 (100%)

Query: 1   MEAAHFFEGTEKLLEVWFSRQQPDANQGSGDLRTIPRSEWDILLKDVQCSIISVTKTDKQ 60
           MEAAHFFEGTEKLLEVWFSRQQPDANQGSGDLRTIPRSEWDILLKDVQCSIISVTKTDKQ
Sbjct: 1   MEAAHFFEGTEKLLEVWFSRQQPDANQGSGDLRTIPRSEWDILLKDVQCSIISVTKTDKQ 60

Query: 61  EAYVLSESSMFVSKRRFILKTCGTTLLLKALVPLLKLARDYSGFDSIQSFFYSRKNFMKP 120
           EAYVLSESSMFVSKRRFILKTCGTTLLLKALVPLLKLARDYSGFDSIQSFFYSRKNFMKP
Sbjct: 61  EAYVLSESSMFVSKRRFILKTCGTTLLLKALVPLLKLARDYSGFDSIQSFFYSRKNFMKP 120

Query: 121 SHQGYPHRNFQEEIEFLNAIFPNGAAYCMGRMNSDCWYLYTLDFPESRVISQPDQTLEIL 180
           SHQGYPHRNFQEEIEFLNAIFPNGAAYCMGRMNSDCWYLYTLDFPESRVISQPDQTLEIL
Sbjct: 121 SHQGYPHRNFQEEIEFLNAIFPNGAAYCMGRMNSDCWYLYTLDFPESRVISQPDQTLEIL 180

Query: 181 MSELDPAVMDQFYMKDGVTAKDVTRESGIRDLIPGSVIDATMFNPCGYSMNGMKSDGTYW 240
           MSELDPAVMDQFYMKDGVTAKDVTRESGIRDLIPGSVIDATMFNPCGYSMNGMKSDGTYW
Sbjct: 181 MSELDPAVMDQFYMKDGVTAKDVTRESGIRDLIPGSVIDATMFNPCGYSMNGMKSDGTYW 240

Query: 241 TIHITPEPEFSYVSFETNLSQTSYDDLIRKVVEVFKPGKFVTTLFVNQSSKCRTVLASPQ 300
           TIHITPEPEFSYVSFETNLSQTSYDDLIRKVVEVFKPGKFVTTLFVNQSSKCRTVLASPQ
Sbjct: 241 TIHITPEPEFSYVSFETNLSQTSYDDLIRKVVEVFKPGKFVTTLFVNQSSKCRTVLASPQ 300

Query: 301 KIEGFKRLDCQSAMFNDYNFVFTSFAKKQQQQQS 334
           KIEGFKRLDCQSAMFNDYNFVFTSFAKKQQQQQS
Sbjct: 301 KIEGFKRLDCQSAMFNDYNFVFTSFAKKQQQQQS 334


>gi|74275348 adenosylmethionine decarboxylase 1 isoform 2 [Homo
           sapiens]
          Length = 186

 Score =  382 bits (981), Expect = e-106
 Identities = 186/186 (100%), Positives = 186/186 (100%)

Query: 149 MGRMNSDCWYLYTLDFPESRVISQPDQTLEILMSELDPAVMDQFYMKDGVTAKDVTRESG 208
           MGRMNSDCWYLYTLDFPESRVISQPDQTLEILMSELDPAVMDQFYMKDGVTAKDVTRESG
Sbjct: 1   MGRMNSDCWYLYTLDFPESRVISQPDQTLEILMSELDPAVMDQFYMKDGVTAKDVTRESG 60

Query: 209 IRDLIPGSVIDATMFNPCGYSMNGMKSDGTYWTIHITPEPEFSYVSFETNLSQTSYDDLI 268
           IRDLIPGSVIDATMFNPCGYSMNGMKSDGTYWTIHITPEPEFSYVSFETNLSQTSYDDLI
Sbjct: 61  IRDLIPGSVIDATMFNPCGYSMNGMKSDGTYWTIHITPEPEFSYVSFETNLSQTSYDDLI 120

Query: 269 RKVVEVFKPGKFVTTLFVNQSSKCRTVLASPQKIEGFKRLDCQSAMFNDYNFVFTSFAKK 328
           RKVVEVFKPGKFVTTLFVNQSSKCRTVLASPQKIEGFKRLDCQSAMFNDYNFVFTSFAKK
Sbjct: 121 RKVVEVFKPGKFVTTLFVNQSSKCRTVLASPQKIEGFKRLDCQSAMFNDYNFVFTSFAKK 180

Query: 329 QQQQQS 334
           QQQQQS
Sbjct: 181 QQQQQS 186


>gi|169167822 PREDICTED: similar to hCG17429 [Homo sapiens]
          Length = 353

 Score =  189 bits (480), Expect = 3e-48
 Identities = 104/163 (63%), Positives = 107/163 (65%), Gaps = 48/163 (29%)

Query: 168 RVISQPDQTLEILMSELDPAVMDQFYMKDGVTAKDVTRESGIRDLIPGSVIDATMFNPCG 227
           +VISQPDQTLE LMS LDPAVMDQFYMKDGVTAKDV  ESGI +LIPGSVI+ATMFNP G
Sbjct: 239 KVISQPDQTLENLMSGLDPAVMDQFYMKDGVTAKDVICESGIHNLIPGSVINATMFNPYG 298

Query: 228 YSMNGMKSDGTYWTIHITPEPEFSYVSFETNLSQTSYDDLIRKVVEVFKPGKFVTTLFVN 287
           YSMNGMKSDGTYWTIHITPEPE  Y                                   
Sbjct: 299 YSMNGMKSDGTYWTIHITPEPESFY----------------------------------- 323

Query: 288 QSSKCRTVLASPQKIEGFKRLDCQSAMFNDYNFVFTSFAKKQQ 330
                        KIEGFKRLDCQSAMFNDYNFVFTSFAKKQQ
Sbjct: 324 -------------KIEGFKRLDCQSAMFNDYNFVFTSFAKKQQ 353



 Score = 72.0 bits (175), Expect = 7e-13
 Identities = 34/39 (87%), Positives = 35/39 (89%)

Query: 1   MEAAHFFEGTEKLLEVWFSRQQPDANQGSGDLRTIPRSE 39
           MEA HF EGTEK LEVWFS QQP+ANQGSGDLRTIPRSE
Sbjct: 200 MEAVHFSEGTEKQLEVWFSWQQPNANQGSGDLRTIPRSE 238


>gi|169167904 PREDICTED: similar to hCG17429 [Homo sapiens]
          Length = 353

 Score =  189 bits (480), Expect = 3e-48
 Identities = 104/163 (63%), Positives = 107/163 (65%), Gaps = 48/163 (29%)

Query: 168 RVISQPDQTLEILMSELDPAVMDQFYMKDGVTAKDVTRESGIRDLIPGSVIDATMFNPCG 227
           +VISQPDQTLE LMS LDPAVMDQFYMKDGVTAKDV  ESGI +LIPGSVI+ATMFNP G
Sbjct: 239 KVISQPDQTLENLMSGLDPAVMDQFYMKDGVTAKDVICESGIHNLIPGSVINATMFNPYG 298

Query: 228 YSMNGMKSDGTYWTIHITPEPEFSYVSFETNLSQTSYDDLIRKVVEVFKPGKFVTTLFVN 287
           YSMNGMKSDGTYWTIHITPEPE  Y                                   
Sbjct: 299 YSMNGMKSDGTYWTIHITPEPESFY----------------------------------- 323

Query: 288 QSSKCRTVLASPQKIEGFKRLDCQSAMFNDYNFVFTSFAKKQQ 330
                        KIEGFKRLDCQSAMFNDYNFVFTSFAKKQQ
Sbjct: 324 -------------KIEGFKRLDCQSAMFNDYNFVFTSFAKKQQ 353



 Score = 72.0 bits (175), Expect = 7e-13
 Identities = 34/39 (87%), Positives = 35/39 (89%)

Query: 1   MEAAHFFEGTEKLLEVWFSRQQPDANQGSGDLRTIPRSE 39
           MEA HF EGTEK LEVWFS QQP+ANQGSGDLRTIPRSE
Sbjct: 200 MEAVHFSEGTEKRLEVWFSWQQPNANQGSGDLRTIPRSE 238


>gi|239742531 PREDICTED: similar to hCG17429 [Homo sapiens]
          Length = 353

 Score =  189 bits (480), Expect = 3e-48
 Identities = 104/163 (63%), Positives = 107/163 (65%), Gaps = 48/163 (29%)

Query: 168 RVISQPDQTLEILMSELDPAVMDQFYMKDGVTAKDVTRESGIRDLIPGSVIDATMFNPCG 227
           +VISQPDQTLE LMS LDPAVMDQFYMKDGVTAKDV  ESGI +LIPGSVI+ATMFNP G
Sbjct: 239 KVISQPDQTLENLMSGLDPAVMDQFYMKDGVTAKDVICESGIHNLIPGSVINATMFNPYG 298

Query: 228 YSMNGMKSDGTYWTIHITPEPEFSYVSFETNLSQTSYDDLIRKVVEVFKPGKFVTTLFVN 287
           YSMNGMKSDGTYWTIHITPEPE  Y                                   
Sbjct: 299 YSMNGMKSDGTYWTIHITPEPESFY----------------------------------- 323

Query: 288 QSSKCRTVLASPQKIEGFKRLDCQSAMFNDYNFVFTSFAKKQQ 330
                        KIEGFKRLDCQSAMFNDYNFVFTSFAKKQQ
Sbjct: 324 -------------KIEGFKRLDCQSAMFNDYNFVFTSFAKKQQ 353



 Score = 72.0 bits (175), Expect = 7e-13
 Identities = 34/39 (87%), Positives = 35/39 (89%)

Query: 1   MEAAHFFEGTEKLLEVWFSRQQPDANQGSGDLRTIPRSE 39
           MEA HF EGTEK LEVWFS QQP+ANQGSGDLRTIPRSE
Sbjct: 200 MEAVHFSEGTEKRLEVWFSWQQPNANQGSGDLRTIPRSE 238


>gi|21687001 DNA-damage-inducible transcript 4-like [Homo sapiens]
          Length = 193

 Score = 31.2 bits (69), Expect = 1.4
 Identities = 14/36 (38%), Positives = 19/36 (52%), Gaps = 1/36 (2%)

Query: 226 CGYSMNGMKSDGTYWTIHITPEPEFSYVSFETNLSQ 261
           CGY    + SD  YW  ++ PEP  + V FE +  Q
Sbjct: 21  CGYHPESLLSDFDYWD-YVVPEPNLNEVIFEESTCQ 55


>gi|120953264 folliculin interacting protein 1 isoform 2 [Homo
           sapiens]
          Length = 1138

 Score = 29.3 bits (64), Expect = 5.2
 Identities = 29/99 (29%), Positives = 46/99 (46%), Gaps = 11/99 (11%)

Query: 35  IPRSEWDILLKDVQCSIISVTKTDKQEAYVLSESSMFVSKRRFILKTCGT----TLLLKA 90
           I  S  ++L    +C +IS   +D QE     E+++ V + R  L+TC      T++   
Sbjct: 605 IQNSSKELLGISDECQMIS--PSDCQE-----ENAVDVKQYRDKLRTCFDAKLETVVCTG 657

Query: 91  LVPLLKLARDYSGFDSIQSFFYSRKNFMKPSHQGYPHRN 129
            VP+ K A   SG +S +  + S K     SH G   R+
Sbjct: 658 SVPVDKCALSESGLESTEETWQSEKLLDSDSHTGKAMRS 696


>gi|120953291 folliculin interacting protein 1 isoform 1 [Homo
           sapiens]
          Length = 1166

 Score = 29.3 bits (64), Expect = 5.2
 Identities = 29/99 (29%), Positives = 46/99 (46%), Gaps = 11/99 (11%)

Query: 35  IPRSEWDILLKDVQCSIISVTKTDKQEAYVLSESSMFVSKRRFILKTCGT----TLLLKA 90
           I  S  ++L    +C +IS   +D QE     E+++ V + R  L+TC      T++   
Sbjct: 633 IQNSSKELLGISDECQMIS--PSDCQE-----ENAVDVKQYRDKLRTCFDAKLETVVCTG 685

Query: 91  LVPLLKLARDYSGFDSIQSFFYSRKNFMKPSHQGYPHRN 129
            VP+ K A   SG +S +  + S K     SH G   R+
Sbjct: 686 SVPVDKCALSESGLESTEETWQSEKLLDSDSHTGKAMRS 724


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.134    0.402 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,012,137
Number of Sequences: 37866
Number of extensions: 494011
Number of successful extensions: 890
Number of sequences better than 10.0: 8
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 879
Number of HSP's gapped (non-prelim): 14
length of query: 334
length of database: 18,247,518
effective HSP length: 103
effective length of query: 231
effective length of database: 14,347,320
effective search space: 3314230920
effective search space used: 3314230920
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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