Search of human proteins with 71834346

Search of human proteins with 71834346

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|71834346 sterile alpha motif domain containing 5 [Homo
sapiens]
         (173 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|71834346 sterile alpha motif domain containing 5 [Homo sapiens]    359   e-100
gi|222136583 inositol polyphosphate phosphatase-like 1 [Homo sap...    53   2e-07
gi|111118978 ephrin receptor EphB2 isoform 1 precursor [Homo sap...    50   1e-06
gi|21396504 ephrin receptor EphB2 isoform 2 precursor [Homo sapi...    50   1e-06
gi|32528301 EPH receptor B4 precursor [Homo sapiens]                   50   1e-06
gi|221625422 ephrin receptor EphA5 isoform b precursor [Homo sap...    50   1e-06
gi|221625401 ephrin receptor EphA5 isoform a precursor [Homo sap...    50   1e-06
gi|32967311 ephrin receptor EphA2 [Homo sapiens]                       50   1e-06
gi|45935385 SAM and SH3 domain containing 1 [Homo sapiens]             49   2e-06
gi|21264337 ArfGAP with RhoGAP domain, ankyrin repeat and PH dom...    49   2e-06
gi|92091600 ArfGAP with RhoGAP domain, ankyrin repeat and PH dom...    49   2e-06
gi|4758280 ephrin receptor EphA4 [Homo sapiens]                        48   4e-06
gi|18079216 CASK interacting protein 1 [Homo sapiens]                  48   5e-06
gi|4758284 ephrin receptor EphB1 precursor [Homo sapiens]              47   6e-06
gi|50511947 cajalin 2 isoform b [Homo sapiens]                         47   8e-06
gi|50511945 cajalin 2 isoform a [Homo sapiens]                         47   8e-06
gi|10047134 cajalin 2 isoform c [Homo sapiens]                         47   8e-06
gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]       46   1e-05
gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]       46   1e-05
gi|140161500 ankyrin repeat and sterile alpha motif domain conta...    45   2e-05
gi|17975768 ephrin receptor EphB3 precursor [Homo sapiens]             45   2e-05
gi|4758282 ephrin receptor EphA7 [Homo sapiens]                        44   5e-05
gi|145312251 EPH receptor A6 isoform a [Homo sapiens]                  43   1e-04
gi|10140845 ephrin receptor EphA8 isoform 1 precursor [Homo sapi...    42   3e-04
gi|150456460 EPH receptor A10 isofom 3 [Homo sapiens]                  41   5e-04
gi|221316650 ephrin receptor EphA1 [Homo sapiens]                      41   6e-04
gi|9506363 SAM and SH3 domain containing 3 [Homo sapiens]              39   0.002
gi|48762709 SAM domain, SH3 domain and nuclear localization sign...    39   0.002
gi|21264592 ArfGAP with RhoGAP domain, ankyrin repeat and PH dom...    39   0.002
gi|226817313 SH3 and multiple ankyrin repeat domains 2 isoform 1...    35   0.025

>gi|71834346 sterile alpha motif domain containing 5 [Homo sapiens]
          Length = 173

 Score =  359 bits (921), Expect = e-100
 Identities = 173/173 (100%), Positives = 173/173 (100%)

Query: 1   MCTNIVYEWLKALQLPQYAESFVDNGYDDLEVCKQIGDPDLDAIGVLAPAHRRRILEAVR 60
           MCTNIVYEWLKALQLPQYAESFVDNGYDDLEVCKQIGDPDLDAIGVLAPAHRRRILEAVR
Sbjct: 1   MCTNIVYEWLKALQLPQYAESFVDNGYDDLEVCKQIGDPDLDAIGVLAPAHRRRILEAVR 60

Query: 61  RLREQDANAAGLYFTLEPQPAPPGPPADAVPTGRRGEPCGGPAQGTRGDSRGHTTAPRSR 120
           RLREQDANAAGLYFTLEPQPAPPGPPADAVPTGRRGEPCGGPAQGTRGDSRGHTTAPRSR
Sbjct: 61  RLREQDANAAGLYFTLEPQPAPPGPPADAVPTGRRGEPCGGPAQGTRGDSRGHTTAPRSR 120

Query: 121 ELVSYPKLKLKIMIRDKLVRDGIHLSKPPYSRKVPMAGILEYLMNWPKSSQSR 173
           ELVSYPKLKLKIMIRDKLVRDGIHLSKPPYSRKVPMAGILEYLMNWPKSSQSR
Sbjct: 121 ELVSYPKLKLKIMIRDKLVRDGIHLSKPPYSRKVPMAGILEYLMNWPKSSQSR 173


>gi|222136583 inositol polyphosphate phosphatase-like 1 [Homo sapiens]
          Length = 1258

 Score = 52.8 bits (125), Expect = 2e-07
 Identities = 23/52 (44%), Positives = 34/52 (65%)

Query: 9    WLKALQLPQYAESFVDNGYDDLEVCKQIGDPDLDAIGVLAPAHRRRILEAVR 60
            WL+A+ L +Y E  V NG+DDLE    I + DL+  GV  PAH+R +L+ ++
Sbjct: 1204 WLRAIGLERYEEGLVHNGWDDLEFLSDITEEDLEEAGVQDPAHKRLLLDTLQ 1255


>gi|111118978 ephrin receptor EphB2 isoform 1 precursor [Homo
           sapiens]
          Length = 986

 Score = 50.1 bits (118), Expect = 1e-06
 Identities = 22/62 (35%), Positives = 39/62 (62%)

Query: 4   NIVYEWLKALQLPQYAESFVDNGYDDLEVCKQIGDPDLDAIGVLAPAHRRRILEAVRRLR 63
           N V EWL+A+++ QY ESF + G+   +V  Q+   D+  +GV    H+++IL +++ +R
Sbjct: 916 NTVDEWLEAIKMGQYKESFANAGFTSFDVVSQMMMEDILRVGVTLAGHQKKILNSIQVMR 975

Query: 64  EQ 65
            Q
Sbjct: 976 AQ 977


>gi|21396504 ephrin receptor EphB2 isoform 2 precursor [Homo
           sapiens]
          Length = 987

 Score = 50.1 bits (118), Expect = 1e-06
 Identities = 22/62 (35%), Positives = 39/62 (62%)

Query: 4   NIVYEWLKALQLPQYAESFVDNGYDDLEVCKQIGDPDLDAIGVLAPAHRRRILEAVRRLR 63
           N V EWL+A+++ QY ESF + G+   +V  Q+   D+  +GV    H+++IL +++ +R
Sbjct: 917 NTVDEWLEAIKMGQYKESFANAGFTSFDVVSQMMMEDILRVGVTLAGHQKKILNSIQVMR 976

Query: 64  EQ 65
            Q
Sbjct: 977 AQ 978


>gi|32528301 EPH receptor B4 precursor [Homo sapiens]
          Length = 987

 Score = 50.1 bits (118), Expect = 1e-06
 Identities = 23/60 (38%), Positives = 37/60 (61%)

Query: 6   VYEWLKALQLPQYAESFVDNGYDDLEVCKQIGDPDLDAIGVLAPAHRRRILEAVRRLREQ 65
           V EWL+A+++ +Y ESF   G+   E+  QI   DL  IGV    H+++IL +V+ ++ Q
Sbjct: 912 VGEWLRAIKMGRYEESFAAAGFGSFELVSQISAEDLLRIGVTLAGHQKKILASVQHMKSQ 971


>gi|221625422 ephrin receptor EphA5 isoform b precursor [Homo sapiens]
          Length = 1015

 Score = 49.7 bits (117), Expect = 1e-06
 Identities = 20/63 (31%), Positives = 40/63 (63%)

Query: 6    VYEWLKALQLPQYAESFVDNGYDDLEVCKQIGDPDLDAIGVLAPAHRRRILEAVRRLREQ 65
            V EWL+A+++ +Y E F++NGY  ++   Q+   DL  +GV    H+++I+ +++ ++ Q
Sbjct: 948  VGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGHQKKIMNSLQEMKVQ 1007

Query: 66   DAN 68
              N
Sbjct: 1008 LVN 1010


>gi|221625401 ephrin receptor EphA5 isoform a precursor [Homo sapiens]
          Length = 1037

 Score = 49.7 bits (117), Expect = 1e-06
 Identities = 20/63 (31%), Positives = 40/63 (63%)

Query: 6    VYEWLKALQLPQYAESFVDNGYDDLEVCKQIGDPDLDAIGVLAPAHRRRILEAVRRLREQ 65
            V EWL+A+++ +Y E F++NGY  ++   Q+   DL  +GV    H+++I+ +++ ++ Q
Sbjct: 970  VGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGHQKKIMNSLQEMKVQ 1029

Query: 66   DAN 68
              N
Sbjct: 1030 LVN 1032


>gi|32967311 ephrin receptor EphA2 [Homo sapiens]
          Length = 976

 Score = 49.7 bits (117), Expect = 1e-06
 Identities = 24/67 (35%), Positives = 41/67 (61%), Gaps = 1/67 (1%)

Query: 6   VYEWLKALQLPQYAESFVDNGYDDLEVCKQIGDPDLDAIGVLAPAHRRRILEAVRRLREQ 65
           V EWL+++++ QY E F+  GY  +E   Q+ + D+  IGV  P H++RI  ++  L++Q
Sbjct: 909 VSEWLESIKMQQYTEHFMAAGYTAIEKVVQMTNDDIKRIGVRLPGHQKRIAYSLLGLKDQ 968

Query: 66  DANAAGL 72
             N  G+
Sbjct: 969 -VNTVGI 974


>gi|45935385 SAM and SH3 domain containing 1 [Homo sapiens]
          Length = 1247

 Score = 49.3 bits (116), Expect = 2e-06
 Identities = 23/64 (35%), Positives = 39/64 (60%)

Query: 6   VYEWLKALQLPQYAESFVDNGYDDLEVCKQIGDPDLDAIGVLAPAHRRRILEAVRRLREQ 65
           V + L  + L ++  +F+ NGY+DL+  K + + DLD + +  P HR  +L AV  L+E 
Sbjct: 638 VEDLLDRINLKEHMPTFLFNGYEDLDTFKLLEEEDLDELNIRDPEHRAVLLTAVELLQEY 697

Query: 66  DANA 69
           D+N+
Sbjct: 698 DSNS 701



 Score = 35.4 bits (80), Expect = 0.025
 Identities = 22/86 (25%), Positives = 33/86 (38%), Gaps = 17/86 (19%)

Query: 2    CTNIVYEWLKALQLPQYAESFVDNGYDDLEVCKQIGDPDLDAIGVLAPAHRRRILEAVRR 61
            C + V +WL ++ LP YA +    G+  L     +    L   G+    H R++L A R 
Sbjct: 1178 CISSVSDWLISIGLPMYAGTLSTAGFSTLSQVPSLSHTCLQEAGITEERHIRKLLSAARL 1237

Query: 62   LREQDANAAGLYFTLEPQPAPPGPPA 87
             +                  PPGP A
Sbjct: 1238 FK-----------------LPPGPEA 1246



 Score = 30.0 bits (66), Expect = 1.0
 Identities = 29/103 (28%), Positives = 41/103 (39%), Gaps = 19/103 (18%)

Query: 80   PAPPGPPADAVPTGRRGEPCGGPAQGTRGDSR-----------------GHTTAPRSREL 122
            PA P  P+D  P      P  G A G+   +R                 G    P     
Sbjct: 1026 PASPTSPSDC-PPALAPRPLSGQAPGSPPSTRPPPWLSELPENTSLQEHGVKLGPALTRK 1084

Query: 123  VSYPK-LKLKIMIRDKLVRDGIHLSKPPYSRKVPMAGILEYLM 164
            VS  + + L+ +  +KL  +GI L++ PYS K    GI E L+
Sbjct: 1085 VSCARGVDLETLTENKLHAEGIDLTEEPYSDKHGRCGIPEALV 1127


>gi|21264337 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain
           3 [Homo sapiens]
          Length = 1544

 Score = 49.3 bits (116), Expect = 2e-06
 Identities = 36/123 (29%), Positives = 52/123 (42%), Gaps = 13/123 (10%)

Query: 9   WLKALQLPQYAESFVDNGYDDLEVCKQIGDPDLDAIGVLAPAHRRRILEAVRRLREQDAN 68
           WL  + L QYA++F  +G       + +G  +L  +G+ A  HR+RIL  ++   E+ + 
Sbjct: 12  WLATVHLEQYADTFRRHGLATAGAARGLGHEELKQLGISATGHRKRILRLLQTGTEEGSL 71

Query: 69  AAGLYFTLE--PQPAPPGPPADAVPTGR-----------RGEPCGGPAQGTRGDSRGHTT 115
                  +E  P PAP   P   VP  R              P   PA G  G SR    
Sbjct: 72  DPKSDSAMEPSPSPAPQAQPPKPVPKPRTVFGGLSGPATTQRPGLSPALGGPGVSRSPEP 131

Query: 116 APR 118
           +PR
Sbjct: 132 SPR 134


>gi|92091600 ArfGAP with RhoGAP domain, ankyrin repeat and PH
          domain 1 isoform c [Homo sapiens]
          Length = 1450

 Score = 48.9 bits (115), Expect = 2e-06
 Identities = 33/92 (35%), Positives = 41/92 (44%), Gaps = 10/92 (10%)

Query: 6  VYEWLKALQLPQYAESFVDNGYDDLEVCKQIGDPDLDAIGVLAPAHRRRILEAVRRLREQ 65
          V EWL+AL L QY   F  +G      C+ + D  L  +G+L P HRRRIL  + R    
Sbjct: 11 VAEWLRALHLEQYTGLFEQHGLVWATECQGLSDTRLMDMGMLLPGHRRRILAGLLRAHTS 70

Query: 66 DANAAGLYFTLEPQPAP------PGPPADAVP 91
           A A        P+P P        PP  A P
Sbjct: 71 PAPAP----RPTPRPVPMKRHIFRSPPVPATP 98


>gi|4758280 ephrin receptor EphA4 [Homo sapiens]
          Length = 986

 Score = 48.1 bits (113), Expect = 4e-06
 Identities = 21/60 (35%), Positives = 36/60 (60%)

Query: 6   VYEWLKALQLPQYAESFVDNGYDDLEVCKQIGDPDLDAIGVLAPAHRRRILEAVRRLREQ 65
           V +WL+A+++ +Y ++F   GY  LE    +   DL  IG+ A  H+ +IL +V+ +R Q
Sbjct: 916 VGDWLQAIKMDRYKDNFTAAGYTTLEAVVHVNQEDLARIGITAITHQNKILSSVQAMRTQ 975


>gi|18079216 CASK interacting protein 1 [Homo sapiens]
          Length = 1431

 Score = 47.8 bits (112), Expect = 5e-06
 Identities = 28/95 (29%), Positives = 42/95 (44%), Gaps = 15/95 (15%)

Query: 9   WLKALQLPQYAESFVDNGYDDLEVCKQIGDPDLDAIGVLAPAHRRRILEAVRRLREQDAN 68
           WL  + L QY +  VDNGY++++    I   DL  IG+    H+++++ AVR+L E    
Sbjct: 549 WLSMIGLAQYYKVLVDNGYENIDFITDITWEDLQEIGITKLGHQKKLMLAVRKLAELQKA 608

Query: 69  AAGLY---------------FTLEPQPAPPGPPAD 88
               Y                 +E  P P   PAD
Sbjct: 609 EYAKYEGGPLRRKAPQSLEVMAIESPPPPEPTPAD 643



 Score = 46.2 bits (108), Expect = 1e-05
 Identities = 25/61 (40%), Positives = 33/61 (54%), Gaps = 1/61 (1%)

Query: 6   VYEWLKALQLPQYAESFVDNGYDDLEVCKQIGDPDLDAIGVLAPAHRRRILEAVRRLREQ 65
           V +WL A QL  YA +F+  GY DL    ++   DL AIGV  P HR++I   +  L   
Sbjct: 477 VSQWLTAFQLQLYAPNFISAGY-DLPTISRMTPEDLTAIGVTKPGHRKKIAAEISGLSIP 535

Query: 66  D 66
           D
Sbjct: 536 D 536



 Score = 27.3 bits (59), Expect = 6.7
 Identities = 24/82 (29%), Positives = 35/82 (42%), Gaps = 17/82 (20%)

Query: 78   PQPAPPGPPADAVPTGRRGEPCGGPAQGTRGDSRGHTTAPRS-RELVSYPKLKLKIMIRD 136
            P+  PP PPA+  PT     P   P     G++R     P S + +++ P  KL+     
Sbjct: 1189 PELPPPPPPAEPPPTDLAHLP---PLPPPEGEARKPAKPPVSPKPVLTQPVPKLQ----- 1240

Query: 137  KLVRDGIHLSKPPYSRKVPMAG 158
                     S  P S+KVP+ G
Sbjct: 1241 --------GSPTPTSKKVPLPG 1254


>gi|4758284 ephrin receptor EphB1 precursor [Homo sapiens]
          Length = 984

 Score = 47.4 bits (111), Expect = 6e-06
 Identities = 20/60 (33%), Positives = 37/60 (61%)

Query: 6   VYEWLKALQLPQYAESFVDNGYDDLEVCKQIGDPDLDAIGVLAPAHRRRILEAVRRLREQ 65
           V +WL A+++ QY +SF+  G+  L++  Q+   DL  IG+    H+++IL ++  +R Q
Sbjct: 916 VDDWLSAIKMVQYRDSFLTAGFTSLQLVTQMTSEDLLRIGITLAGHQKKILNSIHSMRVQ 975


>gi|50511947 cajalin 2 isoform b [Homo sapiens]
          Length = 510

 Score = 47.0 bits (110), Expect = 8e-06
 Identities = 23/59 (38%), Positives = 38/59 (64%), Gaps = 2/59 (3%)

Query: 6  VYEWLKALQLPQYAESFVDNGYDDLEV--CKQIGDPDLDAIGVLAPAHRRRILEAVRRL 62
          V +WL+++ LPQY    + NG+D+++      + D DL  IG+L   HR+RIL+A++ L
Sbjct: 41 VGQWLESIGLPQYENHLMANGFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLL 99



 Score = 40.0 bits (92), Expect = 0.001
 Identities = 24/83 (28%), Positives = 43/83 (51%), Gaps = 2/83 (2%)

Query: 6   VYEWLKALQLPQYAESFVDNGYDDLEVCKQIGDPDL-DAIGVLAPAHRRRILEAV-RRLR 63
           V EWL +++L  Y ++F+ NGY  +++ K+I + +L + + +    HR+RIL ++  RL 
Sbjct: 115 VAEWLDSIELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRLH 174

Query: 64  EQDANAAGLYFTLEPQPAPPGPP 86
           +          TL        PP
Sbjct: 175 DDPPQKPPRSITLREPSGNHTPP 197


>gi|50511945 cajalin 2 isoform a [Homo sapiens]
          Length = 1248

 Score = 47.0 bits (110), Expect = 8e-06
 Identities = 23/59 (38%), Positives = 38/59 (64%), Gaps = 2/59 (3%)

Query: 6   VYEWLKALQLPQYAESFVDNGYDDLEV--CKQIGDPDLDAIGVLAPAHRRRILEAVRRL 62
           V +WL+++ LPQY    + NG+D+++      + D DL  IG+L   HR+RIL+A++ L
Sbjct: 815 VGQWLESIGLPQYENHLMANGFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLL 873



 Score = 40.0 bits (92), Expect = 0.001
 Identities = 24/83 (28%), Positives = 43/83 (51%), Gaps = 2/83 (2%)

Query: 6   VYEWLKALQLPQYAESFVDNGYDDLEVCKQIGDPDL-DAIGVLAPAHRRRILEAV-RRLR 63
           V EWL +++L  Y ++F+ NGY  +++ K+I + +L + + +    HR+RIL ++  RL 
Sbjct: 889 VAEWLDSIELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRLH 948

Query: 64  EQDANAAGLYFTLEPQPAPPGPP 86
           +          TL        PP
Sbjct: 949 DDPPQKPPRSITLREPSGNHTPP 971


>gi|10047134 cajalin 2 isoform c [Homo sapiens]
          Length = 414

 Score = 47.0 bits (110), Expect = 8e-06
 Identities = 23/59 (38%), Positives = 38/59 (64%), Gaps = 2/59 (3%)

Query: 6  VYEWLKALQLPQYAESFVDNGYDDLEV--CKQIGDPDLDAIGVLAPAHRRRILEAVRRL 62
          V +WL+++ LPQY    + NG+D+++      + D DL  IG+L   HR+RIL+A++ L
Sbjct: 41 VGQWLESIGLPQYENHLMANGFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLL 99



 Score = 42.4 bits (98), Expect = 2e-04
 Identities = 28/94 (29%), Positives = 46/94 (48%), Gaps = 14/94 (14%)

Query: 6   VYEWLKALQLPQYAESFVDNGYDDLEVCKQIGDPDL-DAIGVLAPAHRRRILEAVRRLRE 64
           V EWL +++L  Y ++F+ NGY  +++ K+I + +L + + +    HR+RIL        
Sbjct: 115 VAEWLDSIELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRIL-------- 166

Query: 65  QDANAAGLYFTLEPQPAPPGPPADAVPTGRRGEP 98
                A L   L   P    P +  + TG  GEP
Sbjct: 167 -----ASLGDRLHDDPPQKPPRSITLRTGDWGEP 195


>gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]
          Length = 1120

 Score = 46.2 bits (108), Expect = 1e-05
 Identities = 22/57 (38%), Positives = 34/57 (59%)

Query: 8   EWLKALQLPQYAESFVDNGYDDLEVCKQIGDPDLDAIGVLAPAHRRRILEAVRRLRE 64
           EWL AL LPQY +  V +GYD + +   +   +L  IGV    H+++++  V+RL E
Sbjct: 483 EWLCALGLPQYHKQLVSSGYDSMGLVADLTWEELQEIGVNKLGHQKKLMLGVKRLAE 539



 Score = 42.0 bits (97), Expect = 3e-04
 Identities = 20/57 (35%), Positives = 30/57 (52%), Gaps = 1/57 (1%)

Query: 6   VYEWLKALQLPQYAESFVDNGYDDLEVCKQIGDPDLDAIGVLAPAHRRRILEAVRRL 62
           ++ WL   QL  Y   F+  GYD +    ++   DL AIGV  P HR++I   + +L
Sbjct: 412 IHNWLSEFQLEGYTAHFLQAGYD-VPTISRMTPEDLTAIGVTKPGHRKKIASEIAQL 467


>gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]
          Length = 1202

 Score = 46.2 bits (108), Expect = 1e-05
 Identities = 22/57 (38%), Positives = 34/57 (59%)

Query: 8   EWLKALQLPQYAESFVDNGYDDLEVCKQIGDPDLDAIGVLAPAHRRRILEAVRRLRE 64
           EWL AL LPQY +  V +GYD + +   +   +L  IGV    H+++++  V+RL E
Sbjct: 565 EWLCALGLPQYHKQLVSSGYDSMGLVADLTWEELQEIGVNKLGHQKKLMLGVKRLAE 621



 Score = 42.0 bits (97), Expect = 3e-04
 Identities = 20/57 (35%), Positives = 30/57 (52%), Gaps = 1/57 (1%)

Query: 6   VYEWLKALQLPQYAESFVDNGYDDLEVCKQIGDPDLDAIGVLAPAHRRRILEAVRRL 62
           ++ WL   QL  Y   F+  GYD +    ++   DL AIGV  P HR++I   + +L
Sbjct: 494 IHNWLSEFQLEGYTAHFLQAGYD-VPTISRMTPEDLTAIGVTKPGHRKKIASEIAQL 549


>gi|140161500 ankyrin repeat and sterile alpha motif domain
           containing 1 [Homo sapiens]
          Length = 1134

 Score = 45.4 bits (106), Expect = 2e-05
 Identities = 23/59 (38%), Positives = 35/59 (59%), Gaps = 2/59 (3%)

Query: 6   VYEWLKALQLPQYAESFVDNGYDDLEV--CKQIGDPDLDAIGVLAPAHRRRILEAVRRL 62
           V EWL+++ L QY    + NG+DD+       + + DL  IG+  P HRR++L+A R L
Sbjct: 701 VGEWLESIGLQQYESKLLLNGFDDVHFLGSNVMEEQDLRDIGISDPQHRRKLLQAARSL 759



 Score = 35.4 bits (80), Expect = 0.025
 Identities = 17/55 (30%), Positives = 31/55 (56%), Gaps = 1/55 (1%)

Query: 6   VYEWLKALQLPQYAESFVDNGYDDLEVCKQIGDPDL-DAIGVLAPAHRRRILEAV 59
           V  WL +L L  Y  SF+ +GY  ++  K + + +L + + V    HR+RI+ ++
Sbjct: 775 VPSWLDSLGLQDYVHSFLSSGYSSIDTVKNLWELELVNVLKVQLLGHRKRIIASL 829


>gi|17975768 ephrin receptor EphB3 precursor [Homo sapiens]
          Length = 998

 Score = 45.4 bits (106), Expect = 2e-05
 Identities = 21/60 (35%), Positives = 37/60 (61%)

Query: 6   VYEWLKALQLPQYAESFVDNGYDDLEVCKQIGDPDLDAIGVLAPAHRRRILEAVRRLREQ 65
           V +WL A+++ +Y ESFV  G+   ++  Q+   DL  IGV    H+++IL +++ +R Q
Sbjct: 930 VGDWLDAIKMGRYKESFVSAGFASFDLVAQMTAEDLLRIGVTLAGHQKKILSSIQDMRLQ 989


>gi|4758282 ephrin receptor EphA7 [Homo sapiens]
          Length = 998

 Score = 44.3 bits (103), Expect = 5e-05
 Identities = 17/60 (28%), Positives = 39/60 (65%)

Query: 6   VYEWLKALQLPQYAESFVDNGYDDLEVCKQIGDPDLDAIGVLAPAHRRRILEAVRRLREQ 65
           V EWL+A+++ +Y ++F   GY+ LE   ++   D+ ++G+    H+++I+ +++ +R Q
Sbjct: 928 VGEWLQAIKMERYKDNFTAAGYNSLESVARMTIEDVMSLGITLVGHQKKIMSSIQTMRAQ 987


>gi|145312251 EPH receptor A6 isoform a [Homo sapiens]
          Length = 1130

 Score = 43.1 bits (100), Expect = 1e-04
 Identities = 18/58 (31%), Positives = 36/58 (62%)

Query: 6    VYEWLKALQLPQYAESFVDNGYDDLEVCKQIGDPDLDAIGVLAPAHRRRILEAVRRLR 63
            V +WL ++++ QY  +FV  G+   ++  ++   D+  IGV+   H+RRI+ +++ LR
Sbjct: 1060 VGDWLDSIKMGQYKNNFVAAGFTTFDLISRMSIDDIRRIGVILIGHQRRIVSSIQTLR 1117


>gi|10140845 ephrin receptor EphA8 isoform 1 precursor [Homo sapiens]
          Length = 1005

 Score = 42.0 bits (97), Expect = 3e-04
 Identities = 17/66 (25%), Positives = 38/66 (57%)

Query: 6    VYEWLKALQLPQYAESFVDNGYDDLEVCKQIGDPDLDAIGVLAPAHRRRILEAVRRLREQ 65
            V +WL ++++ +Y + F   GY  L +  ++   D+ A+G+    H+++IL +++ +R Q
Sbjct: 935  VGDWLDSIRMGRYRDHFAAGGYSSLGMVLRMNAQDVRALGITLMGHQKKILGSIQTMRAQ 994

Query: 66   DANAAG 71
              +  G
Sbjct: 995  LTSTQG 1000


>gi|150456460 EPH receptor A10 isofom 3 [Homo sapiens]
          Length = 1008

 Score = 41.2 bits (95), Expect = 5e-04
 Identities = 19/55 (34%), Positives = 30/55 (54%)

Query: 9   WLKALQLPQYAESFVDNGYDDLEVCKQIGDPDLDAIGVLAPAHRRRILEAVRRLR 63
           WL+AL L +Y +SF   GY  LE   ++   DL ++G+    HR  +L  +  L+
Sbjct: 941 WLEALDLCRYKDSFAAAGYGSLEAVAEMTAQDLVSLGISLAEHREALLSGISALQ 995


>gi|221316650 ephrin receptor EphA1 [Homo sapiens]
          Length = 976

 Score = 40.8 bits (94), Expect = 6e-04
 Identities = 17/59 (28%), Positives = 35/59 (59%)

Query: 6   VYEWLKALQLPQYAESFVDNGYDDLEVCKQIGDPDLDAIGVLAPAHRRRILEAVRRLRE 64
           V EWL+++++ +Y   F   G D +E   ++   DL  +G+  P H++RIL +++  ++
Sbjct: 918 VSEWLESIRMKRYILHFHSAGLDTMECVLELTAEDLTQMGITLPGHQKRILCSIQGFKD 976


>gi|9506363 SAM and SH3 domain containing 3 [Homo sapiens]
          Length = 380

 Score = 39.3 bits (90), Expect = 0.002
 Identities = 17/64 (26%), Positives = 36/64 (56%)

Query: 6   VYEWLKALQLPQYAESFVDNGYDDLEVCKQIGDPDLDAIGVLAPAHRRRILEAVRRLREQ 65
           ++E L+ + L ++  + + NGY  LE  K++ +  L+ + ++ P HR ++L A   L + 
Sbjct: 257 LHELLERIGLEEHTSTLLLNGYQTLEDFKELRETHLNELNIMDPQHRAKLLTAAELLLDY 316

Query: 66  DANA 69
           D  +
Sbjct: 317 DTGS 320


>gi|48762709 SAM domain, SH3 domain and nuclear localization
           signals, 1 [Homo sapiens]
          Length = 373

 Score = 39.3 bits (90), Expect = 0.002
 Identities = 19/59 (32%), Positives = 32/59 (54%)

Query: 8   EWLKALQLPQYAESFVDNGYDDLEVCKQIGDPDLDAIGVLAPAHRRRILEAVRRLREQD 66
           E+L+ + L +Y  + + NGY+ LE  K I +  L  + +  P  RRR+L A     E++
Sbjct: 248 EFLERIHLQEYTSTLLLNGYETLEDLKDIKESHLIELNIENPDDRRRLLSAAENFLEEE 306


>gi|21264592 ArfGAP with RhoGAP domain, ankyrin repeat and PH
          domain 2 [Homo sapiens]
          Length = 1704

 Score = 38.9 bits (89), Expect = 0.002
 Identities = 18/55 (32%), Positives = 32/55 (58%)

Query: 6  VYEWLKALQLPQYAESFVDNGYDDLEVCKQIGDPDLDAIGVLAPAHRRRILEAVR 60
          + ++L ++ L QY   F ++G+  ++ C  I D  L  IG+    HRRRIL+ ++
Sbjct: 11 IKDFLMSINLEQYLLHFHESGFTTVKDCAAINDSLLQKIGISPTGHRRRILKQLQ 65


>gi|226817313 SH3 and multiple ankyrin repeat domains 2 isoform 1
            [Homo sapiens]
          Length = 1849

 Score = 35.4 bits (80), Expect = 0.025
 Identities = 19/60 (31%), Positives = 34/60 (56%), Gaps = 1/60 (1%)

Query: 6    VYEWLKALQLPQYAESFVDNGYDDLEVCKQIGDPDLDAIGVLAPAHRRRILEAVRRLREQ 65
            V +WL++L L ++ E+F+DN  D   +   +   DL  +GV    HR  I  A+++L ++
Sbjct: 1791 VADWLESLNLGEHKEAFMDNEIDGSHL-PNLQKEDLIDLGVTRVGHRMNIERALKQLLDR 1849



 Score = 28.5 bits (62), Expect = 3.0
 Identities = 21/81 (25%), Positives = 34/81 (41%), Gaps = 1/81 (1%)

Query: 78   PQPAPPGPPADAVP-TGRRGEPCGGPAQGTRGDSRGHTTAPRSRELVSYPKLKLKIMIRD 136
            P PAPP PP  A P   +  +P      G   + +    +     ++S     L+ M R+
Sbjct: 1578 PPPAPPPPPGSAQPGMAKVLQPRTSKLWGDVTEIKSPILSGPKANVISELNSILQQMNRE 1637

Query: 137  KLVRDGIHLSKPPYSRKVPMA 157
            KL + G  L  P  ++   +A
Sbjct: 1638 KLAKPGEGLDSPMGAKSASLA 1658


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.138    0.425 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,217,872
Number of Sequences: 37866
Number of extensions: 460308
Number of successful extensions: 6251
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 167
Number of HSP's successfully gapped in prelim test: 170
Number of HSP's that attempted gapping in prelim test: 3975
Number of HSP's gapped (non-prelim): 2316
length of query: 173
length of database: 18,247,518
effective HSP length: 95
effective length of query: 78
effective length of database: 14,650,248
effective search space: 1142719344
effective search space used: 1142719344
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 58 (26.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.