Guide to the Human Genome
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Search of human proteins with 70610136

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|70610136 poly (ADP-ribose) glycohydrolase [Homo sapiens]
         (976 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|70610136 poly (ADP-ribose) glycohydrolase [Homo sapiens]          2007   0.0  
gi|239744057 PREDICTED: PRO1102 [Homo sapiens]                        276   5e-74
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    49   2e-05
gi|55956788 nucleolin [Homo sapiens]                                   43   0.001
gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens]                42   0.004
gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens]                 42   0.004
gi|48255900 SWI/SNF-related matrix-associated actin-dependent re...    41   0.006
gi|48255898 SWI/SNF-related matrix-associated actin-dependent re...    41   0.006
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]    40   0.008
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]    40   0.008
gi|116235478 establishment of cohesion 1 homolog 1 [Homo sapiens]      40   0.008
gi|22035679 AT rich interactive domain 4B isoform 2 [Homo sapiens]     40   0.008
gi|22035677 AT rich interactive domain 4B isoform 1 [Homo sapiens]     40   0.008
gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precu...    40   0.011
gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2 pre...    40   0.011
gi|60097902 filaggrin [Homo sapiens]                                   39   0.024
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1...    39   0.031
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)...    38   0.040
gi|19913406 DNA topoisomerase II, alpha isozyme [Homo sapiens]         38   0.053
gi|16445033 ACRC protein [Homo sapiens]                                38   0.053
gi|104526627 triadin [Homo sapiens]                                    38   0.053
gi|165905591 LIM domain and actin binding 1 isoform c [Homo sapi...    37   0.069
gi|165905589 LIM domain and actin binding 1 isoform a [Homo sapi...    37   0.069
gi|7705373 LIM domain and actin binding 1 isoform b [Homo sapiens]     37   0.069
gi|217330641 IWS1 homolog [Homo sapiens]                               37   0.069
gi|32130516 serologically defined colon cancer antigen 1 [Homo s...    37   0.069
gi|210032580 SET domain containing 1B [Homo sapiens]                   37   0.069
gi|24415404 MDN1, midasin homolog [Homo sapiens]                       37   0.069
gi|55741677 SET domain containing 1A [Homo sapiens]                    37   0.090
gi|14149997 neuroblastoma breakpoint family, member 3 [Homo sapi...    37   0.090

>gi|70610136 poly (ADP-ribose) glycohydrolase [Homo sapiens]
          Length = 976

 Score = 2007 bits (5200), Expect = 0.0
 Identities = 976/976 (100%), Positives = 976/976 (100%)

Query: 1   MNAGPGCEPCTKRPRWGAATTSPAASDARSFPSRQRRVLDPKDAHVQFRVPPSSPACVPG 60
           MNAGPGCEPCTKRPRWGAATTSPAASDARSFPSRQRRVLDPKDAHVQFRVPPSSPACVPG
Sbjct: 1   MNAGPGCEPCTKRPRWGAATTSPAASDARSFPSRQRRVLDPKDAHVQFRVPPSSPACVPG 60

Query: 61  RAGQHRGSATSLVFKQKTITSWMDTKGIKTAESESLDSKENNNTRIESMMSSVQKDNFYQ 120
           RAGQHRGSATSLVFKQKTITSWMDTKGIKTAESESLDSKENNNTRIESMMSSVQKDNFYQ
Sbjct: 61  RAGQHRGSATSLVFKQKTITSWMDTKGIKTAESESLDSKENNNTRIESMMSSVQKDNFYQ 120

Query: 121 HNVEKLENVSQLSLDKSPTEKSTQYLNQHQTAAMCKWQNEGKHTEQLLESEPQTVTLVPE 180
           HNVEKLENVSQLSLDKSPTEKSTQYLNQHQTAAMCKWQNEGKHTEQLLESEPQTVTLVPE
Sbjct: 121 HNVEKLENVSQLSLDKSPTEKSTQYLNQHQTAAMCKWQNEGKHTEQLLESEPQTVTLVPE 180

Query: 181 QFSNANIDRSPQNDDHSDTDSEENRDNQQFLTTVKLANAKQTTEDEQAREAKSHQKCSKS 240
           QFSNANIDRSPQNDDHSDTDSEENRDNQQFLTTVKLANAKQTTEDEQAREAKSHQKCSKS
Sbjct: 181 QFSNANIDRSPQNDDHSDTDSEENRDNQQFLTTVKLANAKQTTEDEQAREAKSHQKCSKS 240

Query: 241 CDPGEDCASCQQDEIDVVPESPLSDVGSEDVGTGPKNDNKLTRQESCLGNSPPFEKESEP 300
           CDPGEDCASCQQDEIDVVPESPLSDVGSEDVGTGPKNDNKLTRQESCLGNSPPFEKESEP
Sbjct: 241 CDPGEDCASCQQDEIDVVPESPLSDVGSEDVGTGPKNDNKLTRQESCLGNSPPFEKESEP 300

Query: 301 ESPMDVDNSKNSCQDSEADEETSPGFDEQEDGSSSQTANKPSRFQARDADIEFRKRYSTK 360
           ESPMDVDNSKNSCQDSEADEETSPGFDEQEDGSSSQTANKPSRFQARDADIEFRKRYSTK
Sbjct: 301 ESPMDVDNSKNSCQDSEADEETSPGFDEQEDGSSSQTANKPSRFQARDADIEFRKRYSTK 360

Query: 361 GGEVRLHFQFEGGESRTGMNDLNAKLPGNISSLNVECRNSKQHGKKDSKITDHFMRLPKA 420
           GGEVRLHFQFEGGESRTGMNDLNAKLPGNISSLNVECRNSKQHGKKDSKITDHFMRLPKA
Sbjct: 361 GGEVRLHFQFEGGESRTGMNDLNAKLPGNISSLNVECRNSKQHGKKDSKITDHFMRLPKA 420

Query: 421 EDRRKEQWETKHQRTERKIPKYVPPHLSPDKKWLGTPIEEMRRMPRCGIRLPLLRPSANH 480
           EDRRKEQWETKHQRTERKIPKYVPPHLSPDKKWLGTPIEEMRRMPRCGIRLPLLRPSANH
Sbjct: 421 EDRRKEQWETKHQRTERKIPKYVPPHLSPDKKWLGTPIEEMRRMPRCGIRLPLLRPSANH 480

Query: 481 TVTIRVDLLRAGEVPKPFPTHYKDLWDNKHVKMPCSEQNLYPVEDENGERTAGSRWELIQ 540
           TVTIRVDLLRAGEVPKPFPTHYKDLWDNKHVKMPCSEQNLYPVEDENGERTAGSRWELIQ
Sbjct: 481 TVTIRVDLLRAGEVPKPFPTHYKDLWDNKHVKMPCSEQNLYPVEDENGERTAGSRWELIQ 540

Query: 541 TALLNKFTRPQNLKDAILKYNVAYSKKWDFTALIDFWDKVLEEAEAQHLYQSILPDMVKI 600
           TALLNKFTRPQNLKDAILKYNVAYSKKWDFTALIDFWDKVLEEAEAQHLYQSILPDMVKI
Sbjct: 541 TALLNKFTRPQNLKDAILKYNVAYSKKWDFTALIDFWDKVLEEAEAQHLYQSILPDMVKI 600

Query: 601 ALCLPNICTQPIPLLKQKMNHSITMSQEQIASLLANAFFCTFPRRNAKMKSEYSSYPDIN 660
           ALCLPNICTQPIPLLKQKMNHSITMSQEQIASLLANAFFCTFPRRNAKMKSEYSSYPDIN
Sbjct: 601 ALCLPNICTQPIPLLKQKMNHSITMSQEQIASLLANAFFCTFPRRNAKMKSEYSSYPDIN 660

Query: 661 FNRLFEGRSSRKPEKLKTLFCYFRRVTEKKPTGLVTFTRQSLEDFPEWERCEKPLTRLHV 720
           FNRLFEGRSSRKPEKLKTLFCYFRRVTEKKPTGLVTFTRQSLEDFPEWERCEKPLTRLHV
Sbjct: 661 FNRLFEGRSSRKPEKLKTLFCYFRRVTEKKPTGLVTFTRQSLEDFPEWERCEKPLTRLHV 720

Query: 721 TYEGTIEENGQGMLQVDFANRFVGGGVTSAGLVQEEIRFLINPELIISRLFTEVLDHNEC 780
           TYEGTIEENGQGMLQVDFANRFVGGGVTSAGLVQEEIRFLINPELIISRLFTEVLDHNEC
Sbjct: 721 TYEGTIEENGQGMLQVDFANRFVGGGVTSAGLVQEEIRFLINPELIISRLFTEVLDHNEC 780

Query: 781 LIITGTEQYSEYTGYAETYRWSRSHEDGSERDDWQRRCTEIVAIDALHFRRYLDQFVPEK 840
           LIITGTEQYSEYTGYAETYRWSRSHEDGSERDDWQRRCTEIVAIDALHFRRYLDQFVPEK
Sbjct: 781 LIITGTEQYSEYTGYAETYRWSRSHEDGSERDDWQRRCTEIVAIDALHFRRYLDQFVPEK 840

Query: 841 MRRELNKAYCGFLRPGVSSENLSAVATGNWGCGAFGGDARLKALIQILAAAAAERDVVYF 900
           MRRELNKAYCGFLRPGVSSENLSAVATGNWGCGAFGGDARLKALIQILAAAAAERDVVYF
Sbjct: 841 MRRELNKAYCGFLRPGVSSENLSAVATGNWGCGAFGGDARLKALIQILAAAAAERDVVYF 900

Query: 901 TFGDSELMRDIYSMHIFLTERKLTVGDVYKLLLRYYNEECRNCSTPGPDIKLYPFIYHAV 960
           TFGDSELMRDIYSMHIFLTERKLTVGDVYKLLLRYYNEECRNCSTPGPDIKLYPFIYHAV
Sbjct: 901 TFGDSELMRDIYSMHIFLTERKLTVGDVYKLLLRYYNEECRNCSTPGPDIKLYPFIYHAV 960

Query: 961 ESCAETADHSGQRTGT 976
           ESCAETADHSGQRTGT
Sbjct: 961 ESCAETADHSGQRTGT 976


>gi|239744057 PREDICTED: PRO1102 [Homo sapiens]
          Length = 153

 Score =  276 bits (707), Expect = 5e-74
 Identities = 135/139 (97%), Positives = 137/139 (98%)

Query: 649 MKSEYSSYPDINFNRLFEGRSSRKPEKLKTLFCYFRRVTEKKPTGLVTFTRQSLEDFPEW 708
           MKSEYSSYPDINFNRLFEGRSSRKPEKLKTLFCYFRRVTEKKPTGLVTFTRQSLEDFPEW
Sbjct: 1   MKSEYSSYPDINFNRLFEGRSSRKPEKLKTLFCYFRRVTEKKPTGLVTFTRQSLEDFPEW 60

Query: 709 ERCEKPLTRLHVTYEGTIEENGQGMLQVDFANRFVGGGVTSAGLVQEEIRFLINPELIIS 768
           ERCEKPLTRLHVTYEGTIEENG+GMLQVDFAN FVGGGVTSAGLVQEEIRFLINPELIIS
Sbjct: 61  ERCEKPLTRLHVTYEGTIEENGRGMLQVDFANHFVGGGVTSAGLVQEEIRFLINPELIIS 120

Query: 769 RLFTEVLDHNECLIITGTE 787
           RLFTEVLDHNECLIIT +E
Sbjct: 121 RLFTEVLDHNECLIITVSE 139


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 42/244 (17%), Positives = 94/244 (38%), Gaps = 1/244 (0%)

Query: 100 ENNNTRIESMMSSVQKDNFYQHNVEKLENVSQLSLDKSPTEKSTQYLNQHQTAAMCKWQN 159
           +++++  +S  SS   D+    + +  ++ S    D S ++ S    +    ++     +
Sbjct: 546 KSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSS 605

Query: 160 EGKHTEQLLESEPQTVTLVPEQFSNANIDRSPQNDDHSDTDSEENRDNQQFLTTVKLANA 219
           +   +    +S   + +      S ++   S    D SD++S ++ DN     +   +N+
Sbjct: 606 DSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNS 665

Query: 220 KQTTEDEQAREAKSHQKCSKSCDPGEDCASCQQDEIDVVPESPLSDVG-SEDVGTGPKND 278
             +++   + ++ S    S S D  +   S    E     +S  SD   S D      +D
Sbjct: 666 SDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSD 725

Query: 279 NKLTRQESCLGNSPPFEKESEPESPMDVDNSKNSCQDSEADEETSPGFDEQEDGSSSQTA 338
           +  +       +S   +     +S    D+S +S   + +D   S    +  D S+S  +
Sbjct: 726 SDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDS 785

Query: 339 NKPS 342
           N  S
Sbjct: 786 NDSS 789



 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 48/264 (18%), Positives = 102/264 (38%), Gaps = 14/264 (5%)

Query: 93  SESLDSKENNNTRIESMMSSVQKDNFYQHNVEKLENVSQLSLDKSPTEKSTQYLNQHQTA 152
           S+S DS ++++++ +S  S     +    +     N S  S D S +  S+   N   ++
Sbjct: 611 SDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSS-DNSDSSDSSNSSNSSDSS 669

Query: 153 AMCKWQNEGKHTEQLLESEPQTVTLVPEQFSNANIDRSPQNDDHSDTDSEENRDNQQFLT 212
                 +    ++    S+        +   ++N   S  + D SD+DS ++ D+    +
Sbjct: 670 DSSDSSDSSSSSDSSNSSDSS------DSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNS 723

Query: 213 TVK-LANAKQTTEDEQAREAKSHQKCSKSCDPGEDC-ASCQQDEIDVVPESPLSDVGSED 270
           +    +N+  +++   + ++      S S D  +   +S   D  D    S  SD  +  
Sbjct: 724 SDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSS 783

Query: 271 VGTGPKN-----DNKLTRQESCLGNSPPFEKESEPESPMDVDNSKNSCQDSEADEETSPG 325
                 N     D+  +   S   +S      S+ +S    D+S +S     ++   S  
Sbjct: 784 DSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSD 843

Query: 326 FDEQEDGSSSQTANKPSRFQARDA 349
             +  DGS S ++N+     + D+
Sbjct: 844 SSDSSDGSDSDSSNRSDSSNSSDS 867



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 43/225 (19%), Positives = 84/225 (37%), Gaps = 14/225 (6%)

Query: 188 DRSPQNDDHSDTDSEENRDNQQFLTTVKLANAKQTTEDEQAREAKSHQKCSKSCDPGEDC 247
           D+S Q DD + +D     D+         AN++         +A  +   SK    G D 
Sbjct: 457 DKSMQGDDPNSSDESNGNDD---------ANSESDNNSSSRGDASYNSDESKDNGNGSDS 507

Query: 248 ASCQQDEIDVVPESPLSDV---GSEDVGTGPKNDNKLTRQESCLGNSPPFEKESEPESPM 304
              + D+ D   ++  SD    G+       K+D+   + +S   +S      S+     
Sbjct: 508 KGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSS 567

Query: 305 DVDNS-KNSCQDSEADEETSPGFDEQEDGSSSQTANKPSRFQARDADIEFRKRYSTKGGE 363
           D D+S  NS  DS++ +  S    + +   SS +++      + D+  +      +K   
Sbjct: 568 DSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSS-DSSDSSDSKSDS 626

Query: 364 VRLHFQFEGGESRTGMNDLNAKLPGNISSLNVECRNSKQHGKKDS 408
            +        +S++  +D N+    + S  +    +S      DS
Sbjct: 627 SKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDS 671



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 49/252 (19%), Positives = 96/252 (38%), Gaps = 11/252 (4%)

Query: 93  SESLDSKENNNTRIESMMSSVQKDNFYQHNVEKLENVSQLSLDKSPTEKSTQYLNQHQTA 152
           S+S DS +++N+  +S  SS   D+    N     N S  S D S +  S+   N   ++
Sbjct: 753 SDSSDSSDSSNSS-DSSDSSDSSDSSDSSNSSD-SNDSSNSSDSSDSSNSSDSSNSSDSS 810

Query: 153 AMCKWQNEGKHTEQLLESEPQTVTLVPEQFSNANIDRSPQNDDHSDTDSEENRDNQQFLT 212
                 ++   ++    S+    +   +  ++++   S  + D SD+DS    D+     
Sbjct: 811 D----SSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSD 866

Query: 213 TVKLANAKQTTEDEQAREAKSHQKCSKSCDPGEDCASCQQDEIDVVPESPLSDVGSEDVG 272
           +   +++  ++    + ++    + S S D  +   S   D  D    S  SD  +    
Sbjct: 867 S---SDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDS 923

Query: 273 TGPKN--DNKLTRQESCLGNSPPFEKESEPESPMDVDNSKNSCQDSEADEETSPGFDEQE 330
           +   N  DN  +   S   +S      S      +  +S NS   S+++   S       
Sbjct: 924 SESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSS 983

Query: 331 DGSSSQTANKPS 342
           D S S  ++  S
Sbjct: 984 DSSDSSDSSDSS 995



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 47/263 (17%), Positives = 93/263 (35%), Gaps = 13/263 (4%)

Query: 91  AESESLDSKENNNTRIESMMSSVQKDNFYQHNVEKLENVSQLSLDKSPTEKSTQYLNQHQ 150
           +ES+S DS   +++   +   S    +    +     + S  S D S +  S+   N   
Sbjct: 629 SESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSD 688

Query: 151 TAAMCKWQNEGKHTEQLLESEPQTVTLVPEQFSNANIDRSPQNDDHSDTDSEENRDNQQF 210
           ++      N  + ++    S+  +        SN+N   S  ++    +DS  + D+   
Sbjct: 689 SSDSSDSSNSSESSDSSDSSDSDSSD--SSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDS 746

Query: 211 LTTVKLANAKQTTEDEQAREAKSHQKCSKSCDPGEDC----ASCQQDEIDVVPESPLSDV 266
             +   +++  +++   + ++      S S D         +S   D  D    S  S+ 
Sbjct: 747 SDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNS 806

Query: 267 G-------SEDVGTGPKNDNKLTRQESCLGNSPPFEKESEPESPMDVDNSKNSCQDSEAD 319
                   S D  +   +D+  +   S   NS      S+     D D+S  S   + +D
Sbjct: 807 SDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSD 866

Query: 320 EETSPGFDEQEDGSSSQTANKPS 342
              S       D S S  +N+ S
Sbjct: 867 SSDSSDSSNSSDSSDSSDSNESS 889



 Score = 40.0 bits (92), Expect = 0.011
 Identities = 32/170 (18%), Positives = 71/170 (41%), Gaps = 4/170 (2%)

Query: 183 SNANIDRSPQNDDHSDTDSEENRDNQQFLTTVKLANAKQTTEDEQAREAKSHQKCSKSCD 242
           S++N + +  NDD+  +DS + + +     +   +N+  +++   +  + S+        
Sbjct: 524 SDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSS 583

Query: 243 PGEDCASCQQDEIDVVPESPLSDVGSEDVGTGPKNDNKLTRQESCLGNSPPFEKESEPES 302
             +   S   D  D    S  SD  S+   +   +D+  ++ +S    S   + +S+ +S
Sbjct: 584 DSDSSDSSDSDSSDSSNSSDSSD-SSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDS 642

Query: 303 P--MDVDNSKNS-CQDSEADEETSPGFDEQEDGSSSQTANKPSRFQARDA 349
                 D+S NS   DS     +S   D  +   SS +++  +   + D+
Sbjct: 643 SDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDS 692



 Score = 39.7 bits (91), Expect = 0.014
 Identities = 30/170 (17%), Positives = 68/170 (40%), Gaps = 10/170 (5%)

Query: 183  SNANIDRSPQNDDHSDTDSEENRDNQQFLTTVKLANAKQTTEDEQAREAKSHQKCSKSCD 242
            S+ + D S  +D    ++S ++ D+ +   +   +++  +++   + ++      S S D
Sbjct: 1123 SSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSD 1182

Query: 243  PGEDCASCQQDEIDVVPESPLSDVGSEDVGTGPKNDNKLTRQESCLGNSPPFEKESEPES 302
              +   S    +     +S  S   S+   +   +D+  +   S   +S      S+   
Sbjct: 1183 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSD 1242

Query: 303  PMDVDNSKNSCQDSEADEETSPGFDEQE----------DGSSSQTANKPS 342
              D  NS +S   S++ + TS   DE +          +GS S + ++ S
Sbjct: 1243 SSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGS 1292



 Score = 38.9 bits (89), Expect = 0.024
 Identities = 45/237 (18%), Positives = 91/237 (38%), Gaps = 8/237 (3%)

Query: 93   SESLDSKENNNTRIESMMSSVQKDNFYQHNVEKLENVSQLSLDKSPTEKSTQYLNQHQTA 152
            S+S DS +++++  +S  SS   D+    +     N S  S D S +  S+   +   ++
Sbjct: 1058 SDSSDSSDSSDSS-DSSDSSDSSDSSESSDSSDSSNSSDSS-DSSDSSDSSDSSDSSDSS 1115

Query: 153  AMCKWQNEGKHTEQLLESEPQTVTLVPEQFSNANIDRSPQNDDHSDT-DSEENRDNQQFL 211
                  N    ++    S+    +   +   ++    S  + D SD+ DS ++ D+    
Sbjct: 1116 DSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSS 1175

Query: 212  TTVKLANAKQTTEDEQAREAKSHQKCSKSCDPGEDC-ASCQQDEIDVVPESPLSDVG--- 267
             +   +++  +++   + ++      S S D  +   +S   D  D    S  SD     
Sbjct: 1176 DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESS 1235

Query: 268  -SEDVGTGPKNDNKLTRQESCLGNSPPFEKESEPESPMDVDNSKNSCQDSEADEETS 323
             S D      + N     +S   +    +   E +S     N  N+  DS++D E S
Sbjct: 1236 DSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGS 1292



 Score = 38.1 bits (87), Expect = 0.040
 Identities = 49/287 (17%), Positives = 111/287 (38%), Gaps = 16/287 (5%)

Query: 66  RGSATSLVFKQKTITSWMDTKGIKTAESESLDSKENNNTRIESMMSSVQKDNFYQHNVE- 124
           RG A+    + K   +  D+KG +  +S+S  + + NN+      ++   DN    + + 
Sbjct: 488 RGDASYNSDESKDNGNGSDSKGAEDDDSDS--TSDTNNSDSNGNGNNGNDDNDKSDSGKG 545

Query: 125 KLENVSQLSLDKSPTEKSTQYLNQHQTAAMCKWQNEGKHTEQLLESEPQTVTLVPEQFSN 184
           K ++    S D S +  S+   +   + +     ++   ++    S+  +        S+
Sbjct: 546 KSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSD------SS 599

Query: 185 ANIDRSPQNDDHSDTDSEENRDNQQFLTTVKLANAKQTTEDEQAREAKSHQKCSKSCDPG 244
            + D S  +D    +DS ++ D++        + ++  + D  ++   S    S S D  
Sbjct: 600 NSSDSSDSSDSSDSSDSSDSSDSKS-----DSSKSESDSSDSDSKSDSSDSNSSDSSDNS 654

Query: 245 EDCASCQQDEIDVVPESPLSDVGSEDVGTGPKNDNKLTRQESCLGNSPPFEKESEPESPM 304
           +   S          +S  S   S    +   +D+  +   S    S      S+ +S  
Sbjct: 655 DSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSD 714

Query: 305 DVDNSKNSCQDSEA--DEETSPGFDEQEDGSSSQTANKPSRFQARDA 349
             D+S ++  DS++    ++S   +  +   SS ++N      + D+
Sbjct: 715 SSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDS 761



 Score = 37.7 bits (86), Expect = 0.053
 Identities = 42/263 (15%), Positives = 93/263 (35%), Gaps = 11/263 (4%)

Query: 93   SESLDSKENNNT-RIESMMSSVQKDNFYQHNVEKLENVSQLSLDKSPTEKSTQYLNQHQT 151
            S+S D  +++++ R +S  SS   D+    N     + S  +   + ++ S    +    
Sbjct: 845  SDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSD 904

Query: 152  AAMCKWQNEGKHTEQLLESEPQTVTLVPEQFSNANIDRSPQNDDHSDTDSEENRDNQQFL 211
            ++     ++   +    +S   +         N+N   S  + D SD+    N  +    
Sbjct: 905  SSDSSNSSDSSDSSNSSDSSESS-----NSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNS 959

Query: 212  TTVKLANAKQTTEDEQAREAKSHQKCSKSCDPGEDCASCQQDEIDVVPESPLSDVGSEDV 271
            +    ++    +    + ++ +    S S D  +   S          +S  S   S   
Sbjct: 960  SDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSS 1019

Query: 272  GTGPKNDNKLTRQESCLGNSPPFEKESEPESPMDVDNSKNSCQDSEADE-----ETSPGF 326
             +   +D+  +   S   +S      S+     D  NS +S   S++ +     ++S   
Sbjct: 1020 DSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1079

Query: 327  DEQEDGSSSQTANKPSRFQARDA 349
            D  E   SS ++N      + D+
Sbjct: 1080 DSSESSDSSDSSNSSDSSDSSDS 1102



 Score = 31.2 bits (69), Expect = 5.0
 Identities = 51/247 (20%), Positives = 93/247 (37%), Gaps = 36/247 (14%)

Query: 188 DRSPQNDDHSDTDSEENRDNQQFLTTVKLANAKQTTEDEQ--------------AREAKS 233
           D   + D H++ D ++   +++    +   N  Q  ED Q               +E+++
Sbjct: 306 DPEGKEDPHNEVDGDKTSKSEENSAGIPEDNGSQRIEDTQKLNHRESKRVENRITKESET 365

Query: 234 HQKCSKSCDPGEDCASCQQDEIDVVPESPLSDVGSEDVGTGPK--NDNKLTRQESCLGNS 291
           H    KS D G +         ++  E    + G ED G          +  Q   +   
Sbjct: 366 HA-VGKSQDKGIEIKGPSSGNRNITKEVGKGNEGKEDKGQHGMILGKGNVKTQGEVVNIE 424

Query: 292 PPFEKESEPESPMDVDNSKNSCQDSEADEETSPGFDEQ----EDGSSSQTANKPSRFQAR 347
            P +K SEP + +      N+  DS +D   S  FD++    +D +SS  +N        
Sbjct: 425 GPGQK-SEPGNKV---GHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGND----- 475

Query: 348 DADIEFRKRYSTKGGEVRLHFQFEGGESRTGMNDLNAK-LPGNISSLNVECRNSKQHGKK 406
           DA+ E     S++G        +   ES+   N  ++K    + S    +  NS  +G  
Sbjct: 476 DANSESDNNSSSRGDA-----SYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNG 530

Query: 407 DSKITDH 413
           ++   D+
Sbjct: 531 NNGNDDN 537



 Score = 30.4 bits (67), Expect = 8.4
 Identities = 45/199 (22%), Positives = 79/199 (39%), Gaps = 15/199 (7%)

Query: 245 EDCASCQQDEIDVVPESPLSDVGSEDVGTGPKNDNKLTRQESCLGNSPPFEKESE--PES 302
           ED A  Q+D   V   +  +D   E +    +N+   +     + +     KE+E  P +
Sbjct: 174 EDVAVVQEDGPQVAGSNNSTDNEDEIIENSCRNEGNTSEITPQINSKRNGTKEAEVTPGT 233

Query: 303 PMD--VDNSKNSCQDSEADEETSPGFDEQED---GSSSQTANKPSRFQARDADIEFRKRY 357
             D  +DNS  S   + ADE+   G  + ED   G+   ++N     + +D   E     
Sbjct: 234 GEDAGLDNSDGSPSGNGADEDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQDHGKEDDHDS 293

Query: 358 ST-KGGEVRLHFQFEGGESRTGMNDLNAKLPGNISSLNVECRNSKQHGKKDSKITDHFMR 416
           S  +  + + ++  EG E      D + ++ G+ +S + E            +I D   +
Sbjct: 294 SIGQNSDSKEYYDPEGKE------DPHNEVDGDKTSKSEENSAGIPEDNGSQRIED-TQK 346

Query: 417 LPKAEDRRKEQWETKHQRT 435
           L   E +R E   TK   T
Sbjct: 347 LNHRESKRVENRITKESET 365


>gi|55956788 nucleolin [Homo sapiens]
          Length = 710

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 51/271 (18%), Positives = 100/271 (36%), Gaps = 43/271 (15%)

Query: 184 NANIDRSPQNDDHSDTDSEENRDNQQFLTTVKLANAKQTTEDEQAREAKSHQKCSKSCDP 243
           N    +   +D+  D DSEE+ ++ +              EDE   E +     + +  P
Sbjct: 136 NGKNAKKEDSDEEEDDDSEEDEEDDE-------------DEDEDEDEIEPAAMKAAAAAP 182

Query: 244 GEDCASCQQDEIDVVPESPLSDVGSED-VGTGPKNDNKLTRQESCLGNSPPFEKESEPES 302
             +    + DE D   +    D   E+ + T P    K  +       +   E E E E 
Sbjct: 183 ASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVA-EDEDEEED 241

Query: 303 PMDVDNSKNSCQDSEADEETSPGFDEQEDGSSSQTANKPSRFQARDADIEFRKRYSTKGG 362
             D D+  +   + + DE+     +E+E+    +   K  +  A+       K+   +G 
Sbjct: 242 DEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKKQKVEGT 301

Query: 363 EV---------RLHFQFEGGESRTGMNDLNAKLPGNISSLNVECRNSKQHGKKDSKITDH 413
           E           L+F     E +TG++D+ AK   +++ ++V    +++ G  D +  + 
Sbjct: 302 EPTTAFNLFVGNLNFNKSAPELKTGISDVFAK--NDLAVVDVRIGMTRKFGYVDFESAED 359

Query: 414 F-----------------MRLPKAEDRRKEQ 427
                             +  PK +D +KE+
Sbjct: 360 LEKALELTGLKVFGNEIKLEKPKGKDSKKER 390



 Score = 31.6 bits (70), Expect = 3.8
 Identities = 45/239 (18%), Positives = 89/239 (37%), Gaps = 22/239 (9%)

Query: 12  KRPRWGAATT------SPAASDARSFPSRQRRVLDPKDAHV---QFRVPPSSPACVPGRA 62
           K+ +  AAT+      SP    A + P+++  V   K A     +  V P+     PG+ 
Sbjct: 51  KKGKKAAATSAKKVVVSPTKKVAVATPAKKAAVTPGKKAAATPAKKTVTPAKAVTTPGKK 110

Query: 63  GQHRGSA-TSLVFKQKTITSWMDTKGIKTAESESLDSKENNNTRIESMMSSVQKDNFYQH 121
           G   G A  +   K+         K  K A+ E  D +E++++  +      + D     
Sbjct: 111 GATPGKALVATPGKKGAAIPAKGAKNGKNAKKEDSDEEEDDDSEEDE-----EDDEDEDE 165

Query: 122 NVEKLENVSQLSLDKSPTEKSTQYLNQHQTAAMCKWQNEGKHTEQLLESEP----QTVTL 177
           + +++E  +  +   +P  +     +            E    E+ +E+ P    +   +
Sbjct: 166 DEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDD-DEEDDSEEEAMETTPAKGKKAAKV 224

Query: 178 VPEQFSNANIDRSPQNDDHSDTDSEENRDNQQFLTTVKLANAKQTTEDEQAREAKSHQK 236
           VP +  N   D   + DD  + D ++  D             ++  E+E  +EA   +K
Sbjct: 225 VPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDD--DDEDDEEEEEEEEEEPVKEAPGKRK 281


>gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens]
          Length = 755

 Score = 41.6 bits (96), Expect = 0.004
 Identities = 47/190 (24%), Positives = 77/190 (40%), Gaps = 24/190 (12%)

Query: 202 EENRDNQQFLTTVKLANAKQTTEDEQAREAKSHQKCSKSCDPGEDCASCQQDEIDVVPES 261
           E+  D  +F       NAK+++ +++A E    ++  + C       SC Q E +    +
Sbjct: 432 EKTEDGGEFEEGASENNAKESSPEKEAEEGCPEKESEEGCPKRGFEGSCSQKESE--EGN 489

Query: 262 PLSDVGSEDVGTGPKNDNKLTRQESCLGNSPPFEKESEPESPMDVDNSKNSCQDSEADEE 321
           P+   GSE+  +  K   K T +  C  N     KESE +             + E++EE
Sbjct: 490 PVR--GSEE-DSPKKESKKKTLKNDCEENG--LAKESEDD------------LNKESEEE 532

Query: 322 TSPGFDEQEDGSSSQTANKPSRFQARDADIEFRKRYSTKGGEVRLHFQFEGGESRTGMND 381
             P  + +ED S  ++    S  Q+ D      + +   G E  L    EG E     N 
Sbjct: 533 VGPTKESEEDDSEKESDEDCSEKQSEDGS---EREFEENGLEKDL--DEEGSEKELHENV 587

Query: 382 LNAKLPGNIS 391
           L+ +L  N S
Sbjct: 588 LDKELEENDS 597


>gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens]
          Length = 755

 Score = 41.6 bits (96), Expect = 0.004
 Identities = 47/190 (24%), Positives = 77/190 (40%), Gaps = 24/190 (12%)

Query: 202 EENRDNQQFLTTVKLANAKQTTEDEQAREAKSHQKCSKSCDPGEDCASCQQDEIDVVPES 261
           E+  D  +F       NAK+++ +++A E    ++  + C       SC Q E +    +
Sbjct: 432 EKTEDGGEFEEGASENNAKESSPEKEAEEGCPEKESEEGCPKRGFEGSCSQKESE--EGN 489

Query: 262 PLSDVGSEDVGTGPKNDNKLTRQESCLGNSPPFEKESEPESPMDVDNSKNSCQDSEADEE 321
           P+   GSE+  +  K   K T +  C  N     KESE +             + E++EE
Sbjct: 490 PVR--GSEE-DSPKKESKKKTLKNDCEENG--LAKESEDD------------LNKESEEE 532

Query: 322 TSPGFDEQEDGSSSQTANKPSRFQARDADIEFRKRYSTKGGEVRLHFQFEGGESRTGMND 381
             P  + +ED S  ++    S  Q+ D      + +   G E  L    EG E     N 
Sbjct: 533 VGPTKESEEDDSEKESDEDCSEKQSEDGS---EREFEENGLEKDL--DEEGSEKELHENV 587

Query: 382 LNAKLPGNIS 391
           L+ +L  N S
Sbjct: 588 LDKELEENDS 597


>gi|48255900 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a2 isoform a [Homo sapiens]
          Length = 1590

 Score = 40.8 bits (94), Expect = 0.006
 Identities = 56/315 (17%), Positives = 125/315 (39%), Gaps = 21/315 (6%)

Query: 64  QHRGSATSLVFKQKTITSWMDTKGIKTAESESLDSKENNNTRIESMMSSVQKDNFYQHNV 123
           Q R    + + +  T+ + +++K  K ++ ++L  +     ++E      Q+    Q + 
Sbjct: 391 QLRQEVVACMRRDTTLETALNSKAYKRSKRQTL-REARMTEKLEKQQKIEQERKRRQKHQ 449

Query: 124 EKLENVSQLSLDKSPTEKSTQYLNQHQTAAMCKW-----QNEGKHTEQLLESEPQTVTLV 178
           E L ++ Q + D     +S     Q  + A+  W     + + K TE++ +   + +   
Sbjct: 450 EYLNSILQHAKDFKEYHRSVAGKIQKLSKAVATWHANTEREQKKETERIEKERMRRLMAE 509

Query: 179 PEQFSNANIDRSPQNDDHSDTDSEENRDNQQFLTTVKLANAKQTTEDEQAREAKSHQKCS 238
            E+     ID+  + D       ++  +    LT +   + +     E+ +  +  +K  
Sbjct: 510 DEEGYRKLIDQ--KKDRRLAYLLQQTDEYVANLTNLVWEHKQAQAAKEKKKRRRRKKKAE 567

Query: 239 KSCDPGEDCASCQQDEIDVVPESPLSDVGSEDVGT-------GPKNDNKLTRQESCLGNS 291
           ++ + GE       + ID    S +SD+  +   T       GP+   K ++ ++ L  +
Sbjct: 568 ENAEGGESALGPDGEPID--ESSQMSDLPVKVTHTETGKVLFGPEAP-KASQLDAWLEMN 624

Query: 292 PPFE---KESEPESPMDVDNSKNSCQDSEADEETSPGFDEQEDGSSSQTANKPSRFQARD 348
           P +E   +    ES  D +      + S  + E     D   +  S + A +      +D
Sbjct: 625 PGYEVAPRSDSEESDSDYEEEDEEEESSRQETEEKILLDPNSEEVSEKDAKQIIETAKQD 684

Query: 349 ADIEFRKRYSTKGGE 363
            D E+  +YS +G +
Sbjct: 685 VDDEYSMQYSARGSQ 699


>gi|48255898 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a2 isoform b [Homo sapiens]
          Length = 1572

 Score = 40.8 bits (94), Expect = 0.006
 Identities = 56/315 (17%), Positives = 125/315 (39%), Gaps = 21/315 (6%)

Query: 64  QHRGSATSLVFKQKTITSWMDTKGIKTAESESLDSKENNNTRIESMMSSVQKDNFYQHNV 123
           Q R    + + +  T+ + +++K  K ++ ++L  +     ++E      Q+    Q + 
Sbjct: 391 QLRQEVVACMRRDTTLETALNSKAYKRSKRQTL-REARMTEKLEKQQKIEQERKRRQKHQ 449

Query: 124 EKLENVSQLSLDKSPTEKSTQYLNQHQTAAMCKW-----QNEGKHTEQLLESEPQTVTLV 178
           E L ++ Q + D     +S     Q  + A+  W     + + K TE++ +   + +   
Sbjct: 450 EYLNSILQHAKDFKEYHRSVAGKIQKLSKAVATWHANTEREQKKETERIEKERMRRLMAE 509

Query: 179 PEQFSNANIDRSPQNDDHSDTDSEENRDNQQFLTTVKLANAKQTTEDEQAREAKSHQKCS 238
            E+     ID+  + D       ++  +    LT +   + +     E+ +  +  +K  
Sbjct: 510 DEEGYRKLIDQ--KKDRRLAYLLQQTDEYVANLTNLVWEHKQAQAAKEKKKRRRRKKKAE 567

Query: 239 KSCDPGEDCASCQQDEIDVVPESPLSDVGSEDVGT-------GPKNDNKLTRQESCLGNS 291
           ++ + GE       + ID    S +SD+  +   T       GP+   K ++ ++ L  +
Sbjct: 568 ENAEGGESALGPDGEPID--ESSQMSDLPVKVTHTETGKVLFGPEAP-KASQLDAWLEMN 624

Query: 292 PPFE---KESEPESPMDVDNSKNSCQDSEADEETSPGFDEQEDGSSSQTANKPSRFQARD 348
           P +E   +    ES  D +      + S  + E     D   +  S + A +      +D
Sbjct: 625 PGYEVAPRSDSEESDSDYEEEDEEEESSRQETEEKILLDPNSEEVSEKDAKQIIETAKQD 684

Query: 349 ADIEFRKRYSTKGGE 363
            D E+  +YS +G +
Sbjct: 685 VDDEYSMQYSARGSQ 699


>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
          Length = 2454

 Score = 40.4 bits (93), Expect = 0.008
 Identities = 88/402 (21%), Positives = 149/402 (37%), Gaps = 70/402 (17%)

Query: 86   KGIKTAESESLDSKENNNTRIESMMSSVQKDNFYQHNVEKLENVSQL------------S 133
            K I+  E  +L SK N    I+S  SS   +   + N +K +  S              S
Sbjct: 1092 KRIELRERRNLSSKRNTK-EIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNS 1150

Query: 134  LDKSPTEKSTQYLNQHQTAAMCKWQN---EGKHTEQLLESEPQTVTLVPEQ-FSNANIDR 189
            L  S   K     +   +      QN   EG   EQ ++   + + L     F  ++ D 
Sbjct: 1151 LRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDE 1210

Query: 190  SPQ-------NDDHSDTDSEENRDNQQFLTTVK--LANAKQTTEDEQAREAKSHQKCSKS 240
            +         +DD  D D E     +  L  +K  L++ +  + D++  E K        
Sbjct: 1211 ALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNE 1270

Query: 241  CDPGEDCASCQQDEIDVVPESPLSDVGSEDVGTGPKNDNKLTRQESCLGNSPPFE-KESE 299
             +PG++ A  Q +          SD  SE+    P+  ++L R +  + +    E K+++
Sbjct: 1271 ENPGDEEAKNQVNSE--------SDSDSEE-SKKPRYRHRLLRHKLTVSDGESGEEKKTK 1321

Query: 300  PESPMDV-----------DNSKNSCQDSEADEETSPGFDEQ-------------EDGSSS 335
            P+   +V           D+  +  Q+S   EE S   DEQ             E+  S 
Sbjct: 1322 PKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSY 1381

Query: 336  QTANKPSRFQARDADIEFRKRYSTKGGEVRLHFQFEGGESRTGMNDLN--AKLPGNISSL 393
            +   K  R + ++      K  S +  E +   + E  E      D N  +K PG     
Sbjct: 1382 KQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPG----- 1436

Query: 394  NVECRNSKQHGKKDSKI-TDHFMRLPKAEDRRKEQWETKHQR 434
              + R   +   KD K+ T+    L + E+RRK   E + +R
Sbjct: 1437 --KGRKKIRKILKDDKLRTETQNALKEEEERRKRIAERERER 1476


>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
          Length = 2492

 Score = 40.4 bits (93), Expect = 0.008
 Identities = 88/402 (21%), Positives = 149/402 (37%), Gaps = 70/402 (17%)

Query: 86   KGIKTAESESLDSKENNNTRIESMMSSVQKDNFYQHNVEKLENVSQL------------S 133
            K I+  E  +L SK N    I+S  SS   +   + N +K +  S              S
Sbjct: 1130 KRIELRERRNLSSKRNTK-EIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNS 1188

Query: 134  LDKSPTEKSTQYLNQHQTAAMCKWQN---EGKHTEQLLESEPQTVTLVPEQ-FSNANIDR 189
            L  S   K     +   +      QN   EG   EQ ++   + + L     F  ++ D 
Sbjct: 1189 LRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDE 1248

Query: 190  SPQ-------NDDHSDTDSEENRDNQQFLTTVK--LANAKQTTEDEQAREAKSHQKCSKS 240
            +         +DD  D D E     +  L  +K  L++ +  + D++  E K        
Sbjct: 1249 ALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNE 1308

Query: 241  CDPGEDCASCQQDEIDVVPESPLSDVGSEDVGTGPKNDNKLTRQESCLGNSPPFE-KESE 299
             +PG++ A  Q +          SD  SE+    P+  ++L R +  + +    E K+++
Sbjct: 1309 ENPGDEEAKNQVNSE--------SDSDSEE-SKKPRYRHRLLRHKLTVSDGESGEEKKTK 1359

Query: 300  PESPMDV-----------DNSKNSCQDSEADEETSPGFDEQ-------------EDGSSS 335
            P+   +V           D+  +  Q+S   EE S   DEQ             E+  S 
Sbjct: 1360 PKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSY 1419

Query: 336  QTANKPSRFQARDADIEFRKRYSTKGGEVRLHFQFEGGESRTGMNDLN--AKLPGNISSL 393
            +   K  R + ++      K  S +  E +   + E  E      D N  +K PG     
Sbjct: 1420 KQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPG----- 1474

Query: 394  NVECRNSKQHGKKDSKI-TDHFMRLPKAEDRRKEQWETKHQR 434
              + R   +   KD K+ T+    L + E+RRK   E + +R
Sbjct: 1475 --KGRKKIRKILKDDKLRTETQNALKEEEERRKRIAERERER 1514


>gi|116235478 establishment of cohesion 1 homolog 1 [Homo sapiens]
          Length = 840

 Score = 40.4 bits (93), Expect = 0.008
 Identities = 75/394 (19%), Positives = 149/394 (37%), Gaps = 51/394 (12%)

Query: 66  RGSATSLVFKQKTITSWMDTKGIKTAESESLDSKENNNTRIESMMSSVQKDNFYQHNVEK 125
           + S T +   QK +      K    ++++S    + N   +E+ MS+            K
Sbjct: 22  KNSETEIQDSQKNLAKKSGPKETIKSQAKSSSESKINQPELETRMSTRSSKAASNDKATK 81

Query: 126 LENVSQLSLDKSPTEKSTQYLNQHQTAAMCKWQNE-----GKHTEQLLESEPQTVTLVPE 180
             N + +++     E + + L+Q +        NE      +  +QL E   +++     
Sbjct: 82  SINKNTVTVRGYSQESTKKKLSQKKLVHENPKANEQLNRRSQRLQQLTEVSRRSLRSREI 141

Query: 181 QFSNANIDRS---PQNDDHSDTDSEENRDNQQFLTTVKLANAKQTTEDEQA--------- 228
           Q     + +S    + +  S T S+ N+ +Q+ +    L     + EDE           
Sbjct: 142 QGQVQAVKQSLPPTKKEQCSSTQSKSNKTSQKHVKRKVLEVKSDSKEDENLVINEVINSP 201

Query: 229 ---REAKSHQK---CSKSCDPG-EDCA--SCQQDEIDVVPESPLSDVGSEDVGTG--PKN 277
              +    HQ    CS  C  G E C   + ++DE   VP +  S+V    + T   PK 
Sbjct: 202 KGKKRKVEHQTACACSSQCTQGSEKCPQKTTRRDETKPVPVT--SEVKRSKMATSVVPKK 259

Query: 278 DNKLTRQESCLGNSPPFEKESEPESPMDVDNSKNSCQDSE-----------ADEETSPGF 326
           +       + +  +    K  +P  P   DN       S+           A E  S   
Sbjct: 260 NEMKKSVHTQVNTNTTLPKSPQPSVPEQSDNELEQAGKSKRGSILQLCEEIAGEIESDNV 319

Query: 327 DEQEDGSSSQTAN--KPSRFQARDADIEFRKRYSTKGGE-VRLHFQFEGGESR------T 377
           + +++ S  ++    KP+  +  +  +E +  +  +  + V+ +  F   +++       
Sbjct: 320 EVKKESSQMESVKEEKPTEIKLEETSVERQILHQKETNQDVQCNRFFPSRKTKPVKCILN 379

Query: 378 GMNDLNAKLPGNISSLNVECRNSKQHGKKDSKIT 411
           G+N  +AK   N + + +   NS QH K DS+++
Sbjct: 380 GINS-SAKKNSNWTKIKLSKFNSVQHNKLDSQVS 412


>gi|22035679 AT rich interactive domain 4B isoform 2 [Homo sapiens]
          Length = 1226

 Score = 40.4 bits (93), Expect = 0.008
 Identities = 52/252 (20%), Positives = 99/252 (39%), Gaps = 13/252 (5%)

Query: 92   ESESLDSKENNNTRIESMMSSVQKDNFYQHNVEKLENVSQLSLDKSPTEKSTQYLNQHQT 151
            E+ S  S + +    ++ M+  +K N  +   + L      S      EK  + LN    
Sbjct: 769  ENSSNSSSDEDEEETKAKMTPTKKYNGLEEKRKSLRTTGFYSGFSEVAEKRIKLLNNSDE 828

Query: 152  AAMCKWQNEGKHTEQLLESEPQTVTLVPEQFSNANIDR--SPQNDDHSDTDSEEN----R 205
                    + K     ++ +    TL  E FS+++ +   SP +    +  +EE+     
Sbjct: 829  RLQNSRAKDRKDVWSSIQGQWPKKTL-KELFSDSDTEAAASPPHPAPEEGVAEESLQTVA 887

Query: 206  DNQQFLTTVKLANAKQTTEDEQAREAKSHQKCSKSCDPGEDCASCQQDEIDVVPESPLSD 265
            + +    +V+L        D +  E K+ +   +  +     ++   +     PESP S 
Sbjct: 888  EEESCSPSVELEKPPPVNVDSKPIEEKTVEVNDRKAEFPSSGSNSVLNTPPTTPESPSSV 947

Query: 266  VGSEDVGTGPKNDNKLTRQESCLGNSPPFEK-ESEPESPMDVDNSKNSCQDSEADEETSP 324
              +E    G +  + +T  E    N       +SE +S ++VD+     QD +++  +SP
Sbjct: 948  TVTE----GSRQQSSVTVSEPLAPNQEEVRSIKSETDSTIEVDSVAGELQDLQSEGNSSP 1003

Query: 325  -GFDEQEDGSSS 335
             GFD     SSS
Sbjct: 1004 AGFDASVSSSSS 1015


>gi|22035677 AT rich interactive domain 4B isoform 1 [Homo sapiens]
          Length = 1312

 Score = 40.4 bits (93), Expect = 0.008
 Identities = 52/252 (20%), Positives = 99/252 (39%), Gaps = 13/252 (5%)

Query: 92   ESESLDSKENNNTRIESMMSSVQKDNFYQHNVEKLENVSQLSLDKSPTEKSTQYLNQHQT 151
            E+ S  S + +    ++ M+  +K N  +   + L      S      EK  + LN    
Sbjct: 855  ENSSNSSSDEDEEETKAKMTPTKKYNGLEEKRKSLRTTGFYSGFSEVAEKRIKLLNNSDE 914

Query: 152  AAMCKWQNEGKHTEQLLESEPQTVTLVPEQFSNANIDR--SPQNDDHSDTDSEEN----R 205
                    + K     ++ +    TL  E FS+++ +   SP +    +  +EE+     
Sbjct: 915  RLQNSRAKDRKDVWSSIQGQWPKKTL-KELFSDSDTEAAASPPHPAPEEGVAEESLQTVA 973

Query: 206  DNQQFLTTVKLANAKQTTEDEQAREAKSHQKCSKSCDPGEDCASCQQDEIDVVPESPLSD 265
            + +    +V+L        D +  E K+ +   +  +     ++   +     PESP S 
Sbjct: 974  EEESCSPSVELEKPPPVNVDSKPIEEKTVEVNDRKAEFPSSGSNSVLNTPPTTPESPSSV 1033

Query: 266  VGSEDVGTGPKNDNKLTRQESCLGNSPPFEK-ESEPESPMDVDNSKNSCQDSEADEETSP 324
              +E    G +  + +T  E    N       +SE +S ++VD+     QD +++  +SP
Sbjct: 1034 TVTE----GSRQQSSVTVSEPLAPNQEEVRSIKSETDSTIEVDSVAGELQDLQSEGNSSP 1089

Query: 325  -GFDEQEDGSSS 335
             GFD     SSS
Sbjct: 1090 AGFDASVSSSSS 1101


>gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1
           precursor [Homo sapiens]
          Length = 513

 Score = 40.0 bits (92), Expect = 0.011
 Identities = 62/286 (21%), Positives = 106/286 (37%), Gaps = 36/286 (12%)

Query: 81  SWMDTKGIKTAES-ESLDSKENNNTRIESMMSSVQKDNFYQHNVEKLENVSQLSLDKSPT 139
           S M++ G+K+ ES E+ +     ++    ++    +  F +  + + ++ S+L  + +  
Sbjct: 230 SRMNSAGMKSKESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSELDDNNTME 289

Query: 140 E---KSTQYLNQHQTAAM-----CKWQNEGKHTEQLLESEPQTVTLVPEQFSNANIDRSP 191
           E    ST+  N   T         K  ++    E L + E Q V     + S      S 
Sbjct: 290 EVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQ 349

Query: 192 QNDDHSDTD--SEENRDNQQFLTTVKLANAKQTTEDEQAREAKSHQKCSKSCDPGEDCAS 249
           +N   S  +  SE   DN    T+         + +E +    SH K     +  +  +S
Sbjct: 350 ENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESS 409

Query: 250 CQQDEIDVVPESPLSDVGSEDVGTGPKNDNKLTRQESCLGNSPPFEKESEPESPMDVDNS 309
              +  +  PESP  +  S   G          +  S    S   E  SE E   D  +S
Sbjct: 410 ESLNFSEESPESPEDENSSSQEG---------LQSHSSSAESQSEESHSE-EDDSDSQDS 459

Query: 310 KNSCQDSEADEETSPGFDEQEDGSSSQTANKPSRFQARDADIEFRK 355
             S +DS + E  S     +EDG            Q ++ +IE RK
Sbjct: 460 SRSKEDSNSTESKS---SSEEDG------------QLKNIEIESRK 490



 Score = 37.7 bits (86), Expect = 0.053
 Identities = 65/298 (21%), Positives = 121/298 (40%), Gaps = 36/298 (12%)

Query: 81  SWMDTKGIKTAESESLDSKENNNTRIES--MMSSVQKDNFYQHNVEK------LENVSQL 132
           S +D +G+++ + ES+ S E  N+R+ S  M S    +N  Q N +       LE+ S+ 
Sbjct: 208 SELDDEGMQSDDPESIRS-ERGNSRMNSAGMKSKESGENSEQANTQDSGGSQLLEHPSRK 266

Query: 133 SLDKS--PTEKSTQYLNQHQTAAMCKWQN-EGKHTEQLLESEPQTVTLVPEQFSNANIDR 189
              KS    E     L+ + T    K  + E  ++     S+P+          ++  D 
Sbjct: 267 IFRKSRISEEDDRSELDDNNTMEEVKSDSTENSNSRDTGLSQPRR---------DSKGDS 317

Query: 190 SPQNDDHSDTDSEENRDNQQFLTTVKLANAKQTTEDEQAREAKSHQKCSKSCDPGEDCAS 249
              + ++   +  +N D     ++ +   + Q    E   E  S  +   + DP      
Sbjct: 318 QEDSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESR-GDNPDPTTSYVE 376

Query: 250 CQQDEIDVVPESPLSDVGSEDVGTGPKNDNKLTRQESCLGNSPPFEKESEPESPMDVDNS 309
            Q+D       S  S+  S    +  K++++  + +S    S  F +ES PESP D ++S
Sbjct: 377 DQED-------SDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEES-PESPEDENSS 428

Query: 310 KNSCQDSEAD--EETSPGFDEQEDGSSSQTANKPSRFQARDADIEFRKRYSTKGGEVR 365
                 S +   E  S     +ED S SQ +++       D++    K  S + G+++
Sbjct: 429 SQEGLQSHSSSAESQSEESHSEEDDSDSQDSSRSKE----DSNSTESKSSSEEDGQLK 482



 Score = 35.4 bits (80), Expect = 0.26
 Identities = 55/295 (18%), Positives = 113/295 (38%), Gaps = 26/295 (8%)

Query: 61  RAGQHRGSATSLVFKQKTITSWMDTKGIKTAESESLDSKENNNTRIESMMSSVQKDNFYQ 120
           R G    S  ++   +++     D+    T+ES  LD+++  +++ E    S Q+    +
Sbjct: 133 RLGSDEDSDDTIQASEESAPQGQDSAQDTTSESRELDNEDRVDSKPEG-GDSTQESESEE 191

Query: 121 HNV-------------EKLENVSQLSLDKSPTEKSTQYLNQHQTAAMCKWQNEGKHTEQL 167
           H V              +L++    S D  P    ++  N    +A  K +  G+++EQ 
Sbjct: 192 HWVGGGSDGESSHGDGSELDDEGMQSDD--PESIRSERGNSRMNSAGMKSKESGENSEQA 249

Query: 168 LESEPQTVTLVPEQFSNA-NIDRSPQNDDHSDTDSEENRDNQQFLTTVKLANAKQTTEDE 226
              +     L+           R  + DD S+ D     +  +  +T + +N++ T   +
Sbjct: 250 NTQDSGGSQLLEHPSRKIFRKSRISEEDDRSELDDNNTMEEVKSDST-ENSNSRDTGLSQ 308

Query: 227 QAREAK------SHQKCSKSCDPGEDCASCQQDEIDVVPESPLSDVGSEDVGTGPKNDNK 280
             R++K      S +  S+      D  S +  +   +     S    E+V +  + DN 
Sbjct: 309 PRRDSKGDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDN- 367

Query: 281 LTRQESCLGNSPPFEKESEPESPMDVDNSKNSCQDSEADEETSPGFDEQEDGSSS 335
                +           SE +S   + +SK+  ++ +AD E+S   +  E+   S
Sbjct: 368 -PDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPES 421


>gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2
           precursor [Homo sapiens]
          Length = 497

 Score = 40.0 bits (92), Expect = 0.011
 Identities = 62/286 (21%), Positives = 106/286 (37%), Gaps = 36/286 (12%)

Query: 81  SWMDTKGIKTAES-ESLDSKENNNTRIESMMSSVQKDNFYQHNVEKLENVSQLSLDKSPT 139
           S M++ G+K+ ES E+ +     ++    ++    +  F +  + + ++ S+L  + +  
Sbjct: 214 SRMNSAGMKSKESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSELDDNNTME 273

Query: 140 E---KSTQYLNQHQTAAM-----CKWQNEGKHTEQLLESEPQTVTLVPEQFSNANIDRSP 191
           E    ST+  N   T         K  ++    E L + E Q V     + S      S 
Sbjct: 274 EVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQ 333

Query: 192 QNDDHSDTD--SEENRDNQQFLTTVKLANAKQTTEDEQAREAKSHQKCSKSCDPGEDCAS 249
           +N   S  +  SE   DN    T+         + +E +    SH K     +  +  +S
Sbjct: 334 ENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESS 393

Query: 250 CQQDEIDVVPESPLSDVGSEDVGTGPKNDNKLTRQESCLGNSPPFEKESEPESPMDVDNS 309
              +  +  PESP  +  S   G          +  S    S   E  SE E   D  +S
Sbjct: 394 ESLNFSEESPESPEDENSSSQEG---------LQSHSSSAESQSEESHSE-EDDSDSQDS 443

Query: 310 KNSCQDSEADEETSPGFDEQEDGSSSQTANKPSRFQARDADIEFRK 355
             S +DS + E  S     +EDG            Q ++ +IE RK
Sbjct: 444 SRSKEDSNSTESKS---SSEEDG------------QLKNIEIESRK 474



 Score = 37.7 bits (86), Expect = 0.053
 Identities = 65/298 (21%), Positives = 121/298 (40%), Gaps = 36/298 (12%)

Query: 81  SWMDTKGIKTAESESLDSKENNNTRIES--MMSSVQKDNFYQHNVEK------LENVSQL 132
           S +D +G+++ + ES+ S E  N+R+ S  M S    +N  Q N +       LE+ S+ 
Sbjct: 192 SELDDEGMQSDDPESIRS-ERGNSRMNSAGMKSKESGENSEQANTQDSGGSQLLEHPSRK 250

Query: 133 SLDKS--PTEKSTQYLNQHQTAAMCKWQN-EGKHTEQLLESEPQTVTLVPEQFSNANIDR 189
              KS    E     L+ + T    K  + E  ++     S+P+          ++  D 
Sbjct: 251 IFRKSRISEEDDRSELDDNNTMEEVKSDSTENSNSRDTGLSQPRR---------DSKGDS 301

Query: 190 SPQNDDHSDTDSEENRDNQQFLTTVKLANAKQTTEDEQAREAKSHQKCSKSCDPGEDCAS 249
              + ++   +  +N D     ++ +   + Q    E   E  S  +   + DP      
Sbjct: 302 QEDSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESR-GDNPDPTTSYVE 360

Query: 250 CQQDEIDVVPESPLSDVGSEDVGTGPKNDNKLTRQESCLGNSPPFEKESEPESPMDVDNS 309
            Q+D       S  S+  S    +  K++++  + +S    S  F +ES PESP D ++S
Sbjct: 361 DQED-------SDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEES-PESPEDENSS 412

Query: 310 KNSCQDSEAD--EETSPGFDEQEDGSSSQTANKPSRFQARDADIEFRKRYSTKGGEVR 365
                 S +   E  S     +ED S SQ +++       D++    K  S + G+++
Sbjct: 413 SQEGLQSHSSSAESQSEESHSEEDDSDSQDSSRSKE----DSNSTESKSSSEEDGQLK 466



 Score = 35.4 bits (80), Expect = 0.26
 Identities = 55/295 (18%), Positives = 113/295 (38%), Gaps = 26/295 (8%)

Query: 61  RAGQHRGSATSLVFKQKTITSWMDTKGIKTAESESLDSKENNNTRIESMMSSVQKDNFYQ 120
           R G    S  ++   +++     D+    T+ES  LD+++  +++ E    S Q+    +
Sbjct: 117 RLGSDEDSDDTIQASEESAPQGQDSAQDTTSESRELDNEDRVDSKPEG-GDSTQESESEE 175

Query: 121 HNV-------------EKLENVSQLSLDKSPTEKSTQYLNQHQTAAMCKWQNEGKHTEQL 167
           H V              +L++    S D  P    ++  N    +A  K +  G+++EQ 
Sbjct: 176 HWVGGGSDGESSHGDGSELDDEGMQSDD--PESIRSERGNSRMNSAGMKSKESGENSEQA 233

Query: 168 LESEPQTVTLVPEQFSNA-NIDRSPQNDDHSDTDSEENRDNQQFLTTVKLANAKQTTEDE 226
              +     L+           R  + DD S+ D     +  +  +T + +N++ T   +
Sbjct: 234 NTQDSGGSQLLEHPSRKIFRKSRISEEDDRSELDDNNTMEEVKSDST-ENSNSRDTGLSQ 292

Query: 227 QAREAK------SHQKCSKSCDPGEDCASCQQDEIDVVPESPLSDVGSEDVGTGPKNDNK 280
             R++K      S +  S+      D  S +  +   +     S    E+V +  + DN 
Sbjct: 293 PRRDSKGDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDN- 351

Query: 281 LTRQESCLGNSPPFEKESEPESPMDVDNSKNSCQDSEADEETSPGFDEQEDGSSS 335
                +           SE +S   + +SK+  ++ +AD E+S   +  E+   S
Sbjct: 352 -PDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPES 405


>gi|60097902 filaggrin [Homo sapiens]
          Length = 4061

 Score = 38.9 bits (89), Expect = 0.024
 Identities = 36/213 (16%), Positives = 73/213 (34%), Gaps = 25/213 (11%)

Query: 182  FSNANIDRSPQNDDHSDTDSEENRDNQQFLTTVKLANAKQTTEDEQAREAKSHQKCSKSC 241
            +   ++DRS  +  H    + + R +     +   + +++T  +EQ+ +   H       
Sbjct: 3773 YHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRETRNEEQSGDGSRH------- 3825

Query: 242  DPGEDCASCQQDEIDVVPESPLSDVGSEDVGTGPKNDNKLTRQESCLGNSPPFEKESEPE 301
                  +  +  E     +S       +    G +   +     S   +S  + ++SE  
Sbjct: 3826 ------SGSRHHEASTQADSSRHSQSGQGESAGSRRSRRQGSSVSQDSDSEAYPEDSERR 3879

Query: 302  SPMDVDNSKNSCQDSEADEETSPGFDEQEDG---------SSSQTANKPSRFQARDADIE 352
            S     N   S ++   D    PG   ++           S S TA +   F +   D  
Sbjct: 3880 SESASRNHHGSSREQSRDGSRHPGSSHRDTASHVQSSPVQSDSSTAKEHGHFSSLSQDSA 3939

Query: 353  FRKRYSTKG---GEVRLHFQFEGGESRTGMNDL 382
            +     ++G        H+Q EG E + G + L
Sbjct: 3940 YHSGIQSRGSPHSSSSYHYQSEGTERQKGQSGL 3972



 Score = 32.0 bits (71), Expect = 2.9
 Identities = 30/154 (19%), Positives = 56/154 (36%), Gaps = 13/154 (8%)

Query: 186  NIDRSPQNDDHSDTDSEENRDNQQFLTTVKLANAKQTTEDEQAREAKSHQKCSKSCDPGE 245
            ++DRS  +  H    + + R +     +   + ++QT +D+Q+ +   H           
Sbjct: 1184 SVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRKDKQSGDGSRHS---------- 1233

Query: 246  DCASCQQDEIDVVPESPLSDVGSEDVGTGPKNDNKLTRQESCLGNSPPFEKESEPESPMD 305
               S   +       S  S VG E   +G +         S   +S     +SE  S   
Sbjct: 1234 --GSRHHEAASWADSSRHSQVGQEQ-SSGSRTSRHQGSSVSQDSDSERHSDDSERLSGSA 1290

Query: 306  VDNSKNSCQDSEADEETSPGFDEQEDGSSSQTAN 339
              N   S ++   D    PGF +++  S   +A+
Sbjct: 1291 SRNHHGSSREQSRDGSRHPGFHQEDRASHGHSAD 1324



 Score = 31.6 bits (70), Expect = 3.8
 Identities = 69/390 (17%), Positives = 144/390 (36%), Gaps = 27/390 (6%)

Query: 61   RAGQHRGSATSLVFKQKTITSWMDTKGIKT-AESESLDSKENNNTRIESMMSSVQKDNFY 119
            R   HRGS+ S V   +  +   DT+ +    ++         + R +S  SS +  +F 
Sbjct: 1383 RDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGRSRSFL 1442

Query: 120  QHNVEKLENVSQLSLDKSPTEKSTQYLNQHQTAAMCKWQNEGKHTEQLLESEPQTVTLVP 179
             + V   E         +P+    Q  ++H+ A      +  +  +  +   P +     
Sbjct: 1443 -YQVSSHEQSESTHGQTAPSTGGRQG-SRHEQARNSSRHSASQDGQDTIRGHPGSSRGGR 1500

Query: 180  E-QFSNANIDRSPQNDDHSDTDSEENRDNQQFLTTVKLANAKQTTEDEQAREAKSHQKCS 238
            +  +   ++DRS  +  H    + + R +     +   + ++QT  +EQ+ +   H   S
Sbjct: 1501 QGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSRHSG-S 1559

Query: 239  KSCDPGEDCASCQQDEIDVVPESPLSDVGSEDVGTGPKNDNKLTRQESCLGNSPPFEKES 298
            +  +P     S +  ++           GS+   T  +  + +++     G+S   E+ S
Sbjct: 1560 RHHEPSTRAGSSRHSQV-----GQGESAGSK---TSRRQGSSVSQDRDSEGHSEDSERRS 1611

Query: 299  EPESPMDVDNSKNSCQD------SEADEETSPGFD-EQEDGSSSQTANKPSRFQARDADI 351
            E  S     +++   +       S  ++  S G   E    S ++ A   S  QA  +  
Sbjct: 1612 ESASRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQE 1671

Query: 352  EFRKRYSTKGGEVRLHFQFEGGESRTGMNDLNAKL--PGNISSLNVECRNSKQHGKKD-- 407
            + R     + G           +S TG    ++ +   GN  S   +  +S+ H ++   
Sbjct: 1672 QARSSPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDT 1731

Query: 408  SKITDHFMRLPKAEDRRKEQWETKHQRTER 437
              ++ H    P    ++  Q  T+ Q  ER
Sbjct: 1732 QSVSAHGQAGP---HQQSHQESTRGQSGER 1758


>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
           [Homo sapiens]
          Length = 651

 Score = 38.5 bits (88), Expect = 0.031
 Identities = 70/326 (21%), Positives = 132/326 (40%), Gaps = 58/326 (17%)

Query: 89  KTAESESLDSKENNNTRIESMMSSVQKDNFYQHNVEKLENVSQLSLDKSPTEKSTQYLNQ 148
           K++++ES DSK+      + +  +V+KD+  +   +  E+    S D     K T+    
Sbjct: 294 KSSDAESEDSKDAKKDS-KKVKKNVKKDDKKKDVKKDTESTDAESGDSKDERKDTK---- 348

Query: 149 HQTAAMCKWQNEGKHTEQLLES-EPQTVTLVPEQFSNANIDRSPQNDDHSDTDSEENRDN 207
            +     K  ++ K T++  ES + ++      +  + N+ ++ +NDD            
Sbjct: 349 -KDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDD------------ 395

Query: 208 QQFLTTVKLANAKQ---TTEDEQAREAKSHQKCSKSCDPGEDCASCQQDEIDVVPESPLS 264
                  K  +AK+   +T+ E   E+K  QK     D  +D    + D      +S  +
Sbjct: 396 -------KKKDAKKITFSTDSESELESKESQK-----DEKKDKKDSKTDN----KKSVKN 439

Query: 265 DVGSEDVGTGPKNDNKLTRQESCLG---------------NSPPFEKESEPESPMDVDNS 309
           D  S D  + PK D+K  +++   G               N+   E ES+ E   D  +S
Sbjct: 440 DEESTDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKDAKKNAESTEMESDLELKKDKKHS 499

Query: 310 ---KNSCQDSEADEETSPGFDEQEDGSSSQTANKPSRFQARDADIEFRKRYSTKGGEVRL 366
              K S +D + D        + E   SS+T  K S  + + +D E  +     G + ++
Sbjct: 500 KEKKGSKKDIKKDARKDTESTDAEFDESSKTGFKTST-KIKGSDTESEESLYKPGAKKKI 558

Query: 367 HFQFEGGESRTGMNDLNAKLPGNISS 392
             + +G  + + M  L +K    +SS
Sbjct: 559 D-ESDGTSANSKMEGLESKRGFRMSS 583



 Score = 37.7 bits (86), Expect = 0.053
 Identities = 60/296 (20%), Positives = 110/296 (37%), Gaps = 31/296 (10%)

Query: 84  DTKGIKTAESESLDSKENNNTRIESMMSSVQKDNFYQHNVEKLENVSQLSLDKSPTEKST 143
           D+K  K   +E L +K  NN + +   S    D   +   E   NV  L L     ++S 
Sbjct: 202 DSKNSKKTNTEFLHTK--NNPKKDLKRSKTSNDPISEICSENSLNVDFLMLVGQSDDESI 259

Query: 144 QYLNQHQTAAMCKWQNEGKHTEQLLESEPQTVTLVPEQFSNANIDRSPQNDDHSDTDSEE 203
            +           W            S   T     +   NA      +++D  D   + 
Sbjct: 260 NF---------DAWLRNYSQNNSKNYSLKYTKYTKKDTKKNAKKSSDAESEDSKDAKKDS 310

Query: 204 NRDNQQFLTTVKLANAKQTTE--DEQAREAKSHQKCSKSCDPGEDCASCQQDEIDVVPES 261
            +  +      K  + K+ TE  D ++ ++K  +K +K  D  +     ++ +    PES
Sbjct: 311 KKVKKNVKKDDKKKDVKKDTESTDAESGDSKDERKDTKK-DKKKLKKDDKKKDTKKYPES 369

Query: 262 PLSDVG--------SEDVGTGPKNDNKLTRQESCLGNSPPFEKESEPESPMDVDNSKNSC 313
             ++ G        S ++    KND+K    +    ++   + ESE ES     + K   
Sbjct: 370 TDTESGDAKDARNDSRNLKKASKNDDKKKDAKKITFST---DSESELESKESQKDEKKDK 426

Query: 314 QDSEADEETSPGFDEQ------EDGSSSQTANKPSRFQARDADIEFRKRYSTKGGE 363
           +DS+ D + S   DE+      E    S+   K  +   +D+  + +K+ + K  E
Sbjct: 427 KDSKTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKDAKKNAE 482


>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
            [Homo sapiens]
          Length = 2073

 Score = 38.1 bits (87), Expect = 0.040
 Identities = 45/183 (24%), Positives = 74/183 (40%), Gaps = 26/183 (14%)

Query: 182  FSNANIDRSPQNDDHSDTDSEENRDNQQFL---------TTVKLANAKQTTEDEQAREAK 232
            F NA+  R+  NDD S+   E ++DN + L         T   L+  +Q  E +   +  
Sbjct: 1214 FKNADPCRNNMNDDSSNL-KEGSKDNPEPLKCKQVWPKGTKRGLSKWRQNKERKTGFKLN 1272

Query: 233  SHQKCSKSCDPGEDCASCQQDEIDVVPESPLSDVGSEDVG-TG----PKNDNKLTRQESC 287
             +       +P E     +Q E      SP      E+V  TG    P+ +N+  R+E+C
Sbjct: 1273 LYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLPQEENR--REETC 1330

Query: 288  LGNSPPFEKESEPESPMDVDNSKNSCQDSEADEETSPGFDEQE---------DGSSSQTA 338
               SP      +PE  +     +   ++ E +EE     +E+E         DG+ SQ  
Sbjct: 1331 APVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEK 1390

Query: 339  NKP 341
             +P
Sbjct: 1391 EEP 1393


>gi|19913406 DNA topoisomerase II, alpha isozyme [Homo sapiens]
          Length = 1531

 Score = 37.7 bits (86), Expect = 0.053
 Identities = 72/333 (21%), Positives = 119/333 (35%), Gaps = 77/333 (23%)

Query: 86   KGIKTAESESLDSKENNNTRIESMMSSVQKDNFYQHNVEKLENVSQLSLDKSPTEKSTQY 145
            KG KT  +E L S      R+   ++   K    + N +K++N +    + SP E   + 
Sbjct: 1201 KGKKTQMAEVLPSPRGQ--RVIPRITIEMKAEAEKKNKKKIKNENT---EGSPQEDGVEL 1255

Query: 146  LNQHQTAAMCKWQNEGKHTEQLLESEPQTVTLVPEQFSNANIDRSPQNDDHSDTDSEENR 205
                Q              E+  + EP T T      +   I +  + +  SD++S+ + 
Sbjct: 1256 EGLKQ------------RLEKKQKREPGTKTKKQTTLAFKPIKKGKKRNPWSDSESDRSS 1303

Query: 206  DNQQFLTTVKLANAKQTTEDEQAREAKSHQKCSKSCDPGEDCASCQQ--DEIDVVPESPL 263
            D   F              + + R A +  K +   D  ED +   +  D+ D VP    
Sbjct: 1304 DESNF---------DVPPRETEPRRAATKTKFTMDLDSDEDFSDFDEKTDDEDFVP---- 1350

Query: 264  SDVGSEDVGTGPKNDNK-LTRQESC--------------LGNSPP---FEKESEPESPMD 305
            SD       T PK  NK L  Q+S               L +SPP   F  E+E  +P+ 
Sbjct: 1351 SDASPPKTKTSPKLSNKELKPQKSVVSDLEADDVKGSVPLSSSPPATHFPDETEITNPVP 1410

Query: 306  VDN---------SKNSCQDSEADEETSP-----------GFDEQEDGSSSQTANKPSRFQ 345
              N         S++S   + A +  +P           G  ++ D + ++   K     
Sbjct: 1411 KKNVTVKKTAAKSQSSTSTTGAKKRAAPKGTKRDPALNSGVSQKPDPAKTKNRRKRKPST 1470

Query: 346  ARDADIEFRKRYS-------TKGGEVRLHFQFE 371
            + D+D  F K  S       +KG     H  F+
Sbjct: 1471 SDDSDSNFEKIVSKAVTSKKSKGESDDFHMDFD 1503


>gi|16445033 ACRC protein [Homo sapiens]
          Length = 691

 Score = 37.7 bits (86), Expect = 0.053
 Identities = 38/158 (24%), Positives = 62/158 (39%), Gaps = 8/158 (5%)

Query: 186 NIDRSPQNDDHSDTDSEENRDNQQFLTTVKLANAKQTTEDEQAREAKSHQKCSKSCDPGE 245
           N D S   DD+SD DSE   DN    +     N+  +   +   +  S      S D   
Sbjct: 152 NSDDSEAPDDNSD-DSEAPDDNSDD-SEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDDNS 209

Query: 246 DCASCQQDEIDVVPESPLSDVGSEDVGT-GPKNDNKLTRQESCLGNSPPFEKESEPESPM 304
           D +    D+ D   +S + D  S+D       +D+     +S   +  P +   + E+P 
Sbjct: 210 DDSDVPDDKSD---DSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPD 266

Query: 305 DVDNSKNSCQDSEADEETSPGFDEQEDGSSSQTANKPS 342
           D  +   +  DS  D E S   D  +D  +S  ++  S
Sbjct: 267 DSSDDSEAPDDSSDDSEASD--DSSDDSEASDDSSDDS 302



 Score = 37.7 bits (86), Expect = 0.053
 Identities = 38/151 (25%), Positives = 61/151 (40%), Gaps = 9/151 (5%)

Query: 186 NIDRSPQNDDHSDTDSEENRDNQQFLTTVKLANAKQTTEDEQAREAKSHQKCSKSCDPGE 245
           N D S   DD+SD DSE   DN    + V   N+  +++D     +  +   S   D   
Sbjct: 162 NSDDSEAPDDNSD-DSEAPDDNSDD-SDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKS 219

Query: 246 DCASCQQDEIDVVPESPLSDVGSEDV-GTGPKNDNKLTRQESCLGNSPPFEKESEPESPM 304
           D +    D  D   +S + D  S+D       +D+     +S   +  P +   + E+P 
Sbjct: 220 DDSDVPDDSSD---DSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPD 276

Query: 305 DVDNSKNSCQDSEADEETSPGFDEQEDGSSS 335
           D  +   +  DS  D E S   D+  D S +
Sbjct: 277 DSSDDSEASDDSSDDSEAS---DDSSDDSEA 304


>gi|104526627 triadin [Homo sapiens]
          Length = 729

 Score = 37.7 bits (86), Expect = 0.053
 Identities = 58/283 (20%), Positives = 113/283 (39%), Gaps = 24/283 (8%)

Query: 88  IKTAESESLDSKENNNTRIESMMSSVQKDNFYQHNVEKLENVS---QLSLDKSPTEKSTQ 144
           I ++E E  D  + +  + E     ++K   ++   EK E      Q  +     EK  +
Sbjct: 113 IISSEDEEDDDGDEDTDKGEIDEPPLRKKEIHKDKTEKQEKPERKIQTKVTHKEKEKGKE 172

Query: 145 YLNQHQTAAMCKWQNEGKHTEQLLESE-PQTVTLVPEQFSNANIDRSPQNDDHSDTDSEE 203
            + + +     K + +  H E++ + E P+T TL  EQ      ++S +         ++
Sbjct: 173 KVREKE-----KPEKKATHKEKIEKKEKPETKTLAKEQKKAKTAEKSEEKTKKEVKGGKQ 227

Query: 204 NRDNQQFLTTVKLANAKQTTEDEQAREAKSHQKCSKSCDPGEDCASCQQDEIDVVPESPL 263
            +  Q   T  K+   ++T    + +E K     SK  +  +  A C+   ID+     L
Sbjct: 228 EKVKQ---TAAKVKEVQKTPSKPKEKEDKEKAAVSKH-EQKDQYAFCRY-MIDIFVHGDL 282

Query: 264 SDVGSEDVGTGPKNDNKLTRQESCLGNSPPFE-KESEP---ESPMDVDNSKNSCQD--SE 317
              G       P    + +R       SP  E KE E    E  +  +  K   +D   +
Sbjct: 283 KP-GQSPAIPPPLPTEQASRPTPA---SPALEEKEGEKKKAEKKVTSETKKKEKEDIKKK 338

Query: 318 ADEETSPGFDEQEDGSSSQTANKPSRFQARDADIEFRKRYSTK 360
           +++ET+   +++E G +S+T     +  A+ A  +  K+  +K
Sbjct: 339 SEKETAIDVEKKEPGKASETKQGTVKIAAQAAAKKDEKKEDSK 381


>gi|165905591 LIM domain and actin binding 1 isoform c [Homo
           sapiens]
          Length = 600

 Score = 37.4 bits (85), Expect = 0.069
 Identities = 56/276 (20%), Positives = 102/276 (36%), Gaps = 42/276 (15%)

Query: 183 SNANIDRSPQNDDHSDTDSEENRDNQQFLTTVKLANAKQTTEDEQAREAKSHQKCSKSCD 242
           S  N D    +  H D  + +N + +      +LANA++T       +A    K      
Sbjct: 289 SKGNYDEGFGHRPHKDLWASKNENEEILERPAQLANARETPHSPGVEDAPI-AKVGVLAA 347

Query: 243 PGEDCASCQQDEIDVVPES--------PLSDVGSEDVGTGPKNDNKLTRQESCLGNSPPF 294
             E  AS QQ++ D   E+        P +++GS   G+  +   K+++ +      PP 
Sbjct: 348 SMEAKASSQQEKEDKPAETKKLRIAWPPPTELGSS--GSALEEGIKMSKPKW-----PPE 400

Query: 295 EKESEPESPMDVDNSKNSCQDSEADEETSPGFD-----EQEDGSSSQTANKPSR------ 343
           ++ S+PE P DVD      + S + +E S  F      +     S +T + P R      
Sbjct: 401 DEISKPEVPEDVDLDLKKLRRSSSLKERSRPFTVAASFQSTSVKSPKTVSPPIRKGWSMS 460

Query: 344 ---------FQARDADIEFRKRYSTKGGEVRLHFQFEGGESRTGMNDLNAKLPGNISSLN 394
                      A    +E  K     G   +  +Q +  +  TG             SL 
Sbjct: 461 EQSEESVGGRVAERKQVENAKASKKNGNVGKTTWQNKESKGETGKRSKEG------HSLE 514

Query: 395 VECRNSKQHGKKDSKITDHFMRLPKAEDRRKEQWET 430
           +E  N  ++G    +  + F++    ++ +   W +
Sbjct: 515 MENENLVENGADSDEDDNSFLKQQSPQEPKSLNWSS 550


>gi|165905589 LIM domain and actin binding 1 isoform a [Homo
           sapiens]
          Length = 760

 Score = 37.4 bits (85), Expect = 0.069
 Identities = 56/276 (20%), Positives = 102/276 (36%), Gaps = 42/276 (15%)

Query: 183 SNANIDRSPQNDDHSDTDSEENRDNQQFLTTVKLANAKQTTEDEQAREAKSHQKCSKSCD 242
           S  N D    +  H D  + +N + +      +LANA++T       +A    K      
Sbjct: 449 SKGNYDEGFGHRPHKDLWASKNENEEILERPAQLANARETPHSPGVEDAPI-AKVGVLAA 507

Query: 243 PGEDCASCQQDEIDVVPES--------PLSDVGSEDVGTGPKNDNKLTRQESCLGNSPPF 294
             E  AS QQ++ D   E+        P +++GS   G+  +   K+++ +      PP 
Sbjct: 508 SMEAKASSQQEKEDKPAETKKLRIAWPPPTELGSS--GSALEEGIKMSKPKW-----PPE 560

Query: 295 EKESEPESPMDVDNSKNSCQDSEADEETSPGFD-----EQEDGSSSQTANKPSR------ 343
           ++ S+PE P DVD      + S + +E S  F      +     S +T + P R      
Sbjct: 561 DEISKPEVPEDVDLDLKKLRRSSSLKERSRPFTVAASFQSTSVKSPKTVSPPIRKGWSMS 620

Query: 344 ---------FQARDADIEFRKRYSTKGGEVRLHFQFEGGESRTGMNDLNAKLPGNISSLN 394
                      A    +E  K     G   +  +Q +  +  TG             SL 
Sbjct: 621 EQSEESVGGRVAERKQVENAKASKKNGNVGKTTWQNKESKGETGKRSKEG------HSLE 674

Query: 395 VECRNSKQHGKKDSKITDHFMRLPKAEDRRKEQWET 430
           +E  N  ++G    +  + F++    ++ +   W +
Sbjct: 675 MENENLVENGADSDEDDNSFLKQQSPQEPKSLNWSS 710


>gi|7705373 LIM domain and actin binding 1 isoform b [Homo sapiens]
          Length = 759

 Score = 37.4 bits (85), Expect = 0.069
 Identities = 56/276 (20%), Positives = 102/276 (36%), Gaps = 42/276 (15%)

Query: 183 SNANIDRSPQNDDHSDTDSEENRDNQQFLTTVKLANAKQTTEDEQAREAKSHQKCSKSCD 242
           S  N D    +  H D  + +N + +      +LANA++T       +A    K      
Sbjct: 448 SKGNYDEGFGHRPHKDLWASKNENEEILERPAQLANARETPHSPGVEDAPI-AKVGVLAA 506

Query: 243 PGEDCASCQQDEIDVVPES--------PLSDVGSEDVGTGPKNDNKLTRQESCLGNSPPF 294
             E  AS QQ++ D   E+        P +++GS   G+  +   K+++ +      PP 
Sbjct: 507 SMEAKASSQQEKEDKPAETKKLRIAWPPPTELGSS--GSALEEGIKMSKPKW-----PPE 559

Query: 295 EKESEPESPMDVDNSKNSCQDSEADEETSPGFD-----EQEDGSSSQTANKPSR------ 343
           ++ S+PE P DVD      + S + +E S  F      +     S +T + P R      
Sbjct: 560 DEISKPEVPEDVDLDLKKLRRSSSLKERSRPFTVAASFQSTSVKSPKTVSPPIRKGWSMS 619

Query: 344 ---------FQARDADIEFRKRYSTKGGEVRLHFQFEGGESRTGMNDLNAKLPGNISSLN 394
                      A    +E  K     G   +  +Q +  +  TG             SL 
Sbjct: 620 EQSEESVGGRVAERKQVENAKASKKNGNVGKTTWQNKESKGETGKRSKEG------HSLE 673

Query: 395 VECRNSKQHGKKDSKITDHFMRLPKAEDRRKEQWET 430
           +E  N  ++G    +  + F++    ++ +   W +
Sbjct: 674 MENENLVENGADSDEDDNSFLKQQSPQEPKSLNWSS 709


>gi|217330641 IWS1 homolog [Homo sapiens]
          Length = 819

 Score = 37.4 bits (85), Expect = 0.069
 Identities = 61/346 (17%), Positives = 131/346 (37%), Gaps = 28/346 (8%)

Query: 137 SPTEKSTQYLNQHQTAAMCKWQNEGKHTEQLLESEPQTVTLVPEQFSNANIDRSPQNDDH 196
           S TE ++++  + ++      +N+G+ TE   +S      +  ++F +++ +        
Sbjct: 315 SETEDASRHKQKPESDDDSDRENKGEDTEMQNDSFHSDSHMDRKKFHSSDSEEEEHKKQK 374

Query: 197 SDTDSEENRDNQQFLTTVKLANAKQTTEDEQAREAKSHQKCSKSCDPGEDCASCQQDEID 256
            D+D +E    ++ +   K A     +EDE+   AK  +  S + D   D  S +  + +
Sbjct: 375 MDSDEDEKEGEEEKVAKRKAA-VLSDSEDEEKASAKKSRVVSDADDSDSDAVSDKSGKRE 433

Query: 257 VVPESPLSDVGSEDVGTGPKNDNKLTRQESCLGNSPP------FEKESEPESPMDVDNSK 310
               S   +   +++      +  L   +S  GN         F +  + E       ++
Sbjct: 434 KTIASDSEEEAGKELSDKKNEEKDLFGSDSESGNEEENLIADIFGESGDEEEEEFTGFNQ 493

Query: 311 NSCQDSEADEETSPGFDEQEDGSSSQTANKPSRFQ-ARDADIEFRKRYSTKGGEVRLHFQ 369
              ++ + + +      E ED  S     +        D ++  +++ S  G   R    
Sbjct: 494 EDLEEEKGETQVK----EAEDSDSDDNIKRGKHMDFLSDFEMMLQRKKSMSGKRRR---N 546

Query: 370 FEGGESRTGMNDLNAKLPGNISSLNVECRNSKQHGKKDSKITDHFMRLPKAEDRRKEQWE 429
            +GG   T ++D +  +   I  +N      +Q   +          LP      K+Q +
Sbjct: 547 RDGG---TFISDADDVVSAMIVKMNEAAEEDRQLNNQKKPALKKLTLLPAVVMHLKKQ-D 602

Query: 430 TKHQRTERKIPKYVPPHLSPDKKWLGTPIEEMRRMPRCGIRLPLLR 475
            K    +  +       +S  K+WL +P+ + R +P   IR  LL+
Sbjct: 603 LKETFIDSGV-------MSAIKEWL-SPLPD-RSLPALKIREELLK 639


>gi|32130516 serologically defined colon cancer antigen 1 [Homo
           sapiens]
          Length = 1076

 Score = 37.4 bits (85), Expect = 0.069
 Identities = 45/277 (16%), Positives = 108/277 (38%), Gaps = 47/277 (16%)

Query: 155 CKWQNEGKHTEQLLESEPQTVTLVPEQFSNANIDRSPQNDDHSDTDSEENRD--NQQFLT 212
           C W+++G+   ++ + + +T+     +  +  +++    D  SD D EE+      + +T
Sbjct: 663 CVWRHQGERKVRVQDEDMETLASCTSELISEEMEQLDGGDTSSDEDKEEHETPVEVELMT 722

Query: 213 TVKLAN---------------AKQTTEDEQARE--AKSHQKCSKSCDPGEDCASCQQDEI 255
            V   +                ++++EDE   E   K      +  D GE+  +     I
Sbjct: 723 QVDQEDITLQSGRDELNEELIQEESSEDEGEYEEVRKDQDSVGEMKDEGEETLNYPDTTI 782

Query: 256 D---VVPESPLSDVGSEDVGTGPKNDNKLTRQESCLGNSPPFEKESEPESPMDVDNSKNS 312
           D   + P+  +  + S++  +   +    +R+          +K+  P    D++    +
Sbjct: 783 DLSHLQPQRSIQKLASKEESSNSSDSKSQSRRHLSAKERREMKKKKLPSDSGDLE----A 838

Query: 313 CQDSEADEETSPGFDEQEDGSSSQTANKPSRFQARDADIEFRKRYSTKGGEVRLHFQFEG 372
            +  + ++E++   +  ++ S +  A +P +   +    + +++Y  +  E R       
Sbjct: 839 LEGKDKEKESTVHIETHQNTSKNVAAVQPMKRGQKSKMKKMKEKYKDQDEEDR------- 891

Query: 373 GESRTGMNDLNAKLPGNISSLNVECRNSKQHGKKDSK 409
                   +L  KL G+  S      N ++ GKK  K
Sbjct: 892 --------ELIMKLLGSAGS------NKEEKGKKGKK 914


>gi|210032580 SET domain containing 1B [Homo sapiens]
          Length = 1923

 Score = 37.4 bits (85), Expect = 0.069
 Identities = 44/189 (23%), Positives = 70/189 (37%), Gaps = 18/189 (9%)

Query: 161  GKHTEQLLESEPQTVTLVPEQFSNANIDRSPQNDDHSDTDSEENRDNQQFLTTVKLANAK 220
            G+  E+   SE Q  T   E+      +    +DD  D D  EN D    L+     +  
Sbjct: 1033 GEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEG 1092

Query: 221  QTTEDE------QAREAKSHQKCSKSCD---PGEDCASCQQDEIDVV------PESPLSD 265
             + E+E         EA S  + S+S +     E   S  +DE +VV       E     
Sbjct: 1093 DSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEEM 1152

Query: 266  VGSEDVGTGPKNDNKLTRQESCLGNSPPFEKESEPESPMDVDNSKNSCQD--SEADEETS 323
            V  E + +    D +   +E+ L    P       E  +D++    + ++  S  DE   
Sbjct: 1153 VAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSMLDEPPL 1212

Query: 324  P-GFDEQED 331
            P G +E  D
Sbjct: 1213 PVGVEEPAD 1221



 Score = 35.0 bits (79), Expect = 0.34
 Identities = 33/166 (19%), Positives = 62/166 (37%), Gaps = 17/166 (10%)

Query: 187  IDRSPQNDDHSDTDSEENRDNQQFLTTVKLANAKQTTEDEQAREAKSHQKCSKSCDPGED 246
            + R P      D+  EE+           L+  +++TE+E+  E +  ++     D  + 
Sbjct: 1019 VRRRPARPLELDSGGEEDEKES-------LSEEQESTEEEEEAEEEEEEEDDDDDDSDDR 1071

Query: 247  CASCQQDEIDVVPESPLSDVGSEDVGTGPKNDNKLTRQESCLGNSPPFEKESEPESPMDV 306
              S   DE     ++ LS+   +D G   + +       S + +       SE     + 
Sbjct: 1072 DESENDDE-----DTALSEASEKDEGDSDEEETV-----SIVTSKAEATSSSESSESSEF 1121

Query: 307  DNSKNSCQDSEADEETSPGFDEQEDGSSSQTANKPSRFQARDADIE 352
            ++S  S   S  DEE     +E+E+    +   + S   A   D E
Sbjct: 1122 ESSSESSPSSSEDEEEVVAREEEEEEEEEEMVAEESMASAGPEDFE 1167


>gi|24415404 MDN1, midasin homolog [Homo sapiens]
          Length = 5596

 Score = 37.4 bits (85), Expect = 0.069
 Identities = 46/217 (21%), Positives = 89/217 (41%), Gaps = 43/217 (19%)

Query: 188  DRSPQNDDHSDTDSEE-----NRDNQQFLTTVKLANAKQTTEDEQAREAKSHQKCSKSCD 242
            D   ++++  D  +EE     + ++ + +      ++  + +D+  ++ K  ++ +++ D
Sbjct: 4782 DDEEEDEEEEDNKTEETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADD 4841

Query: 243  --PGEDCASCQQDEIDV--------------VPESPLSDV------GSEDVGTGPKNDNK 280
               GED  + Q DE D               VPE    D+       SED   G   DN+
Sbjct: 4842 GGQGEDKINEQIDERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDNE 4901

Query: 281  LTRQESCLGNSPPFEK--------------ESEPESPMDVDNSKNSCQDSEADEETSPGF 326
               +E+ L      E+              ++E +SP + +   +    +E +EE   G 
Sbjct: 4902 EGEEENPLEIKEKPEEAGHEAEERGETETDQNESQSPQEPEEGPSEDDKAEGEEEMDTGA 4961

Query: 327  DEQEDGSSSQTANKPSRFQARDADIEFRKRYSTKGGE 363
            D+Q DG ++Q   + S  Q +  + E  K    +GGE
Sbjct: 4962 DDQ-DGDAAQHPEEHSEEQQQSVE-EKDKEADEEGGE 4996


>gi|55741677 SET domain containing 1A [Homo sapiens]
          Length = 1707

 Score = 37.0 bits (84), Expect = 0.090
 Identities = 37/157 (23%), Positives = 60/157 (38%), Gaps = 20/157 (12%)

Query: 158  QNEGKHTEQL-LESEPQTVTLVPEQFSNANIDRSPQNDDHSDTDSEENRDNQQFLTTVKL 216
            + +GKH +   L+SE +           A+ + S + D+  D + EE+ D ++ + T K 
Sbjct: 950  KTQGKHRKSFALDSEGE----------EASQESSSEKDEEDDEEDEEDEDREEAVDTTKK 999

Query: 217  ANAKQTTEDEQAREAKSHQKCSKSCD-PGE-----DCASCQQDEIDVVPESPLSDVGSED 270
                   EDE   E+ S  KCS   D  GE     D  S           S  S   S  
Sbjct: 1000 ETEVSDGEDE---ESDSSSKCSLYADSDGENDSTSDSESSSSSSSSSSSSSSSSSSSSSS 1056

Query: 271  VGTGPKNDNKLTRQESCLGNSPPFEKESEPESPMDVD 307
                   D +   + + L ++ P  +E    +P  V+
Sbjct: 1057 SSESSSEDEEEEERPAALPSASPPPREVPVPTPAPVE 1093



 Score = 32.0 bits (71), Expect = 2.9
 Identities = 86/425 (20%), Positives = 146/425 (34%), Gaps = 71/425 (16%)

Query: 106  IESMMSSVQKDNFYQHNVEKLENVSQLSLDK---SPTEKSTQYLNQHQTAAMCKWQNEGK 162
            ++ M S +Q+D     N + +ENV+  + D+   S  EK+  +    Q AA  + + E K
Sbjct: 799  VQEMKSIMQRDL----NRKMVENVAFGAFDQWWESKEEKAKPF----QNAAKQQAKEEDK 850

Query: 163  HTEQLLESEPQTVTLVPEQFSNANIDRSPQNDDHSDTDSEENRDNQQFLTTVKLANAKQT 222
               +L   EP  ++LV    S               T  E           ++L + K  
Sbjct: 851  EKTKL--KEPGLLSLVDWAKSGGT------------TGIEAFAFGSGLRGALRLPSFKVK 896

Query: 223  TEDEQAREAKSHQKCSKSCDPGEDCASCQQDEIDVVPESPLSDVGSEDVGTGPKNDNKLT 282
             ++       S +K  +   P E+      DE D   E    + G       PK D +  
Sbjct: 897  RKEPSEISEASEEKRPRPSTPAEE------DEDDPEQEKEAGEPGRPGTKP-PKRDEERG 949

Query: 283  RQESCLGNSPPFEKESEPESPMDVDNSKNSCQDSEADEETSPGFDEQEDGSSSQTANKPS 342
            + +     S  F  +SE E      +S+   +D E DEE     D +E   +++   + S
Sbjct: 950  KTQGKHRKS--FALDSEGEEASQESSSEKDEEDDEEDEEDE---DREEAVDTTKKETEVS 1004

Query: 343  RFQARDADIEFR-KRYSTKGGEVRLHFQFEGGESRTGMNDLNAKLPGNISSLNVECRNSK 401
              +  ++D   +   Y+   GE       E   S +  +  ++    + SS      +S 
Sbjct: 1005 DGEDEESDSSSKCSLYADSDGENDSTSDSESSSSSSSSSSSSSSSSSSSSS------SSS 1058

Query: 402  QHGKKDSKITDHFMRLPKAEDRRKEQWETKHQRTERKIPKYV------------------ 443
            +   +D +  +    LP A    +E         E  +P+ V                  
Sbjct: 1059 ESSSEDEEEEERPAALPSASPPPREVPVPTPAPVEVPVPERVAGSPVTPLPEQEASPARP 1118

Query: 444  -------PPH--LSPDKKWLGTPIEEMRRMPRCGIRLPLLRPSANHTVTIRVDLLRAGEV 494
                   PP   L P +   G P    R   R    +PLL P      T+    +     
Sbjct: 1119 AGPTEESPPSAPLRPPEPPAGPPAPAPRPDERPSSPIPLLPPPKKRRKTVSFSAIEVVPA 1178

Query: 495  PKPFP 499
            P+P P
Sbjct: 1179 PEPPP 1183


>gi|14149997 neuroblastoma breakpoint family, member 3 [Homo
           sapiens]
          Length = 633

 Score = 37.0 bits (84), Expect = 0.090
 Identities = 47/217 (21%), Positives = 85/217 (39%), Gaps = 33/217 (15%)

Query: 121 HNVEKLENVSQLSLDKSPTEKSTQYLNQHQTAAMCKWQNEGKHTEQLLESEPQTVTLVPE 180
           H+ E+   ++QL         +++ LNQH  A +   + +      L E   +   L   
Sbjct: 156 HSQER--ELTQLREKLQEGRDASRSLNQHLQALLTPDEPDNSQGRDLREQLAEGCRLAQH 213

Query: 181 QFSNANIDRSPQNDDHSDTD--SEENRDNQQFLTTVKLANAKQTTEDEQARE------AK 232
                    SP+NDD  D D   EE    Q+     ++  A++    E + E      + 
Sbjct: 214 LVQKL----SPENDDDEDEDVKVEEAEKVQELYAPREVQKAEEKEVPEDSLEECAITCSN 269

Query: 233 SHQKCSKSCDPGEDCASCQQDEID-VVPESPLSDVGSEDVGTGPKNDNKLTRQESCLGNS 291
           SH  C  +   G    + ++D++D  + +S   D   + V   P+N++   ++E      
Sbjct: 270 SHHPCESNQPYGNTRITFEEDQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEE------ 323

Query: 292 PPFEKESEPESPMDVDNSKNSCQDSEADEETSPGFDE 328
                E  P SP ++       Q+SE +E     +DE
Sbjct: 324 -----EKGPVSPRNL-------QESEEEEAPQESWDE 348


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.131    0.392 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,638,681
Number of Sequences: 37866
Number of extensions: 1970416
Number of successful extensions: 7972
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 27
Number of HSP's successfully gapped in prelim test: 236
Number of HSP's that attempted gapping in prelim test: 7322
Number of HSP's gapped (non-prelim): 732
length of query: 976
length of database: 18,247,518
effective HSP length: 112
effective length of query: 864
effective length of database: 14,006,526
effective search space: 12101638464
effective search space used: 12101638464
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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