Guide to the Human Genome
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Search of human proteins with 7019555

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7019555 transmembrane protein 2 isoform a [Homo sapiens]
         (1383 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7019555 transmembrane protein 2 isoform a [Homo sapiens]          2830   0.0  
gi|209447096 transmembrane protein 2 isoform b [Homo sapiens]        2199   0.0  
gi|38638698 KIAA1199 [Homo sapiens]                                   896   0.0  
gi|126116589 fibrocystin L [Homo sapiens]                             166   1e-40
gi|126131104 fibrocystin isoform 2 [Homo sapiens]                      66   2e-10
gi|126131102 fibrocystin isoform 1 [Homo sapiens]                      66   2e-10
gi|210147552 O-linked mannose beta1,2-N-acetylglucosaminyltransf...    49   3e-05
gi|20270363 family with sequence similarity 3, member D [Homo sa...    44   0.001
gi|13324682 family 3, member A protein [Homo sapiens]                  42   0.003
gi|91807125 family with sequence similarity 3, member C precurso...    42   0.005
gi|7661714 family with sequence similarity 3, member C precursor...    42   0.005
gi|46255032 family with sequence similarity 3, member B isoform ...    37   0.10 
gi|46255030 family with sequence similarity 3, member B isoform ...    37   0.10 
gi|29294649 dicer1 [Homo sapiens]                                      32   3.2  
gi|29294651 dicer1 [Homo sapiens]                                      32   3.2  
gi|78042577 MAP7 domain containing 1 [Homo sapiens]                    32   4.2  
gi|94400925 synaptonemal complex protein 2-like [Homo sapiens]         32   5.5  
gi|37537554 hypothetical protein FLJ37538 [Homo sapiens]               32   5.5  
gi|62422571 collapsin response mediator protein 1 isoform 1 [Hom...    31   7.2  
gi|4503051 collapsin response mediator protein 1 isoform 2 [Homo...    31   7.2  
gi|21493039 A-kinase anchor protein 4 isoform 2 [Homo sapiens]         31   9.4  
gi|21493037 A-kinase anchor protein 4 isoform 1 [Homo sapiens]         31   9.4  

>gi|7019555 transmembrane protein 2 isoform a [Homo sapiens]
          Length = 1383

 Score = 2830 bits (7337), Expect = 0.0
 Identities = 1383/1383 (100%), Positives = 1383/1383 (100%)

Query: 1    MYATDSRGHSPAFLQPQNGNSRHPSGYVPGKVVPLRPPPPPKSQASAKFTSIRREDRATF 60
            MYATDSRGHSPAFLQPQNGNSRHPSGYVPGKVVPLRPPPPPKSQASAKFTSIRREDRATF
Sbjct: 1    MYATDSRGHSPAFLQPQNGNSRHPSGYVPGKVVPLRPPPPPKSQASAKFTSIRREDRATF 60

Query: 61   AFSPEEQQAQRESQKQKRHKNTFICFAITSFSFFIALAIILGISSKYAPDENCPDQNPRL 120
            AFSPEEQQAQRESQKQKRHKNTFICFAITSFSFFIALAIILGISSKYAPDENCPDQNPRL
Sbjct: 61   AFSPEEQQAQRESQKQKRHKNTFICFAITSFSFFIALAIILGISSKYAPDENCPDQNPRL 120

Query: 121  RNWDPGQDSAKQVVIKEGDMLRLTSDATVHSIVIQDGGLLVFGDNKDGSRNITLRTHYIL 180
            RNWDPGQDSAKQVVIKEGDMLRLTSDATVHSIVIQDGGLLVFGDNKDGSRNITLRTHYIL
Sbjct: 121  RNWDPGQDSAKQVVIKEGDMLRLTSDATVHSIVIQDGGLLVFGDNKDGSRNITLRTHYIL 180

Query: 181  IQDGGALHIGAEKCRYKSKATITLYGKSDEGESMPTFGKKFIGVEAGGTLELHGARKASW 240
            IQDGGALHIGAEKCRYKSKATITLYGKSDEGESMPTFGKKFIGVEAGGTLELHGARKASW
Sbjct: 181  IQDGGALHIGAEKCRYKSKATITLYGKSDEGESMPTFGKKFIGVEAGGTLELHGARKASW 240

Query: 241  TLLARTLNSSGLPFGSYTFEKDFSRGLNVRVIDQDTAKILESERFDTHEYRNESRRLQEF 300
            TLLARTLNSSGLPFGSYTFEKDFSRGLNVRVIDQDTAKILESERFDTHEYRNESRRLQEF
Sbjct: 241  TLLARTLNSSGLPFGSYTFEKDFSRGLNVRVIDQDTAKILESERFDTHEYRNESRRLQEF 300

Query: 301  LRFQDPGRIVAIAVGDSAAKSLLQGTIQMIQERLGSELIQGLGYRQAWALVGVIDGGSTS 360
            LRFQDPGRIVAIAVGDSAAKSLLQGTIQMIQERLGSELIQGLGYRQAWALVGVIDGGSTS
Sbjct: 301  LRFQDPGRIVAIAVGDSAAKSLLQGTIQMIQERLGSELIQGLGYRQAWALVGVIDGGSTS 360

Query: 361  CNESVRNYENHSSGGKALAQREFYTVDGQKFSVTAYSEWIEGVSLSGFRVEVVDGVKLNL 420
            CNESVRNYENHSSGGKALAQREFYTVDGQKFSVTAYSEWIEGVSLSGFRVEVVDGVKLNL
Sbjct: 361  CNESVRNYENHSSGGKALAQREFYTVDGQKFSVTAYSEWIEGVSLSGFRVEVVDGVKLNL 420

Query: 421  LDDVSSWKPGDQIVVASTDYSMYQAEEFTLLPCSECSHFQVKVKETPQFLHMGEIIDGVD 480
            LDDVSSWKPGDQIVVASTDYSMYQAEEFTLLPCSECSHFQVKVKETPQFLHMGEIIDGVD
Sbjct: 421  LDDVSSWKPGDQIVVASTDYSMYQAEEFTLLPCSECSHFQVKVKETPQFLHMGEIIDGVD 480

Query: 481  MRAEVGILTRNIVIQGEVEDSCYAENQCQFFDYDTFGGHIMIMKNFTSVHLSYVELKHMG 540
            MRAEVGILTRNIVIQGEVEDSCYAENQCQFFDYDTFGGHIMIMKNFTSVHLSYVELKHMG
Sbjct: 481  MRAEVGILTRNIVIQGEVEDSCYAENQCQFFDYDTFGGHIMIMKNFTSVHLSYVELKHMG 540

Query: 541  QQQMGRYPVHFHLCGDVDYKGGYRHATFVDGLSIHHSFSRCITVHGTNGLLIKDTIGFDT 600
            QQQMGRYPVHFHLCGDVDYKGGYRHATFVDGLSIHHSFSRCITVHGTNGLLIKDTIGFDT
Sbjct: 541  QQQMGRYPVHFHLCGDVDYKGGYRHATFVDGLSIHHSFSRCITVHGTNGLLIKDTIGFDT 600

Query: 601  LGHCFFLEDGIEQRNTLFHNLGLLTKPGTLLPTDRNNSMCTTMRDKVFGNYIPVPATDCM 660
            LGHCFFLEDGIEQRNTLFHNLGLLTKPGTLLPTDRNNSMCTTMRDKVFGNYIPVPATDCM
Sbjct: 601  LGHCFFLEDGIEQRNTLFHNLGLLTKPGTLLPTDRNNSMCTTMRDKVFGNYIPVPATDCM 660

Query: 661  AVSTFWIAHPNNNLINNAAAGSQDAGIWYLFHKEPTGESSGLQLLAKPELTPLGIFYNNR 720
            AVSTFWIAHPNNNLINNAAAGSQDAGIWYLFHKEPTGESSGLQLLAKPELTPLGIFYNNR
Sbjct: 661  AVSTFWIAHPNNNLINNAAAGSQDAGIWYLFHKEPTGESSGLQLLAKPELTPLGIFYNNR 720

Query: 721  VHSNFKAGLFIDKGVKTTNSSAADPREYLCLDNSARFRPHQDANPEKPRVAALIDRLIAF 780
            VHSNFKAGLFIDKGVKTTNSSAADPREYLCLDNSARFRPHQDANPEKPRVAALIDRLIAF
Sbjct: 721  VHSNFKAGLFIDKGVKTTNSSAADPREYLCLDNSARFRPHQDANPEKPRVAALIDRLIAF 780

Query: 781  KNNDNGAWVRGGDIIVQNSAFADNGIGLTFASDGSFPSDEGSSQEVSESLFVGESRNYGF 840
            KNNDNGAWVRGGDIIVQNSAFADNGIGLTFASDGSFPSDEGSSQEVSESLFVGESRNYGF
Sbjct: 781  KNNDNGAWVRGGDIIVQNSAFADNGIGLTFASDGSFPSDEGSSQEVSESLFVGESRNYGF 840

Query: 841  QGGQNKYVGTGGIDQKPRTLPRNRTFPIRGFQIYDGPIHLTRSTFKKYVPTPDRYSSAIG 900
            QGGQNKYVGTGGIDQKPRTLPRNRTFPIRGFQIYDGPIHLTRSTFKKYVPTPDRYSSAIG
Sbjct: 841  QGGQNKYVGTGGIDQKPRTLPRNRTFPIRGFQIYDGPIHLTRSTFKKYVPTPDRYSSAIG 900

Query: 901  FLMKNSWQITPRNNISLVKFGPHVSLNVFFGKPGPWFEDCEMDGDKNSIFHDIDGSVTGY 960
            FLMKNSWQITPRNNISLVKFGPHVSLNVFFGKPGPWFEDCEMDGDKNSIFHDIDGSVTGY
Sbjct: 901  FLMKNSWQITPRNNISLVKFGPHVSLNVFFGKPGPWFEDCEMDGDKNSIFHDIDGSVTGY 960

Query: 961  KDAYVGRMDNYLIRHPSCVNVSKWNAVICSGTYAQVYVQTWSTQNLSMTITRDEYPSNPM 1020
            KDAYVGRMDNYLIRHPSCVNVSKWNAVICSGTYAQVYVQTWSTQNLSMTITRDEYPSNPM
Sbjct: 961  KDAYVGRMDNYLIRHPSCVNVSKWNAVICSGTYAQVYVQTWSTQNLSMTITRDEYPSNPM 1020

Query: 1021 VLRGINQKAAFPQYQPVVMLEKGYTIHWNGPAPRTTFLYLVNFNKNDWIRVGLCYPSNTS 1080
            VLRGINQKAAFPQYQPVVMLEKGYTIHWNGPAPRTTFLYLVNFNKNDWIRVGLCYPSNTS
Sbjct: 1021 VLRGINQKAAFPQYQPVVMLEKGYTIHWNGPAPRTTFLYLVNFNKNDWIRVGLCYPSNTS 1080

Query: 1081 FQVTFGYLQRQNGSLSKIEEYEPVHSLEELQRKQSERKFYFDSSTGLLFLYLKAKSHRHG 1140
            FQVTFGYLQRQNGSLSKIEEYEPVHSLEELQRKQSERKFYFDSSTGLLFLYLKAKSHRHG
Sbjct: 1081 FQVTFGYLQRQNGSLSKIEEYEPVHSLEELQRKQSERKFYFDSSTGLLFLYLKAKSHRHG 1140

Query: 1141 HSYCSSQGCERVKIQAATDSKDISNCMAKAYPQYYRKPSVVKRMPAMLTGLCQGCGTRQV 1200
            HSYCSSQGCERVKIQAATDSKDISNCMAKAYPQYYRKPSVVKRMPAMLTGLCQGCGTRQV
Sbjct: 1141 HSYCSSQGCERVKIQAATDSKDISNCMAKAYPQYYRKPSVVKRMPAMLTGLCQGCGTRQV 1200

Query: 1201 VFTSDPHKSYLPVQFQSPDKAETQRGDPSVISVNGTDFTFRSAGVLLLVVDPCSVPFRLT 1260
            VFTSDPHKSYLPVQFQSPDKAETQRGDPSVISVNGTDFTFRSAGVLLLVVDPCSVPFRLT
Sbjct: 1201 VFTSDPHKSYLPVQFQSPDKAETQRGDPSVISVNGTDFTFRSAGVLLLVVDPCSVPFRLT 1260

Query: 1261 EKTVFPLADVSRIEEYLKTGIPPRSIVLLSTRGEIKQLNISHLLVPLGLAKPAHLYDKGS 1320
            EKTVFPLADVSRIEEYLKTGIPPRSIVLLSTRGEIKQLNISHLLVPLGLAKPAHLYDKGS
Sbjct: 1261 EKTVFPLADVSRIEEYLKTGIPPRSIVLLSTRGEIKQLNISHLLVPLGLAKPAHLYDKGS 1320

Query: 1321 TIFLGFSGNFKPSWTKLFTSPAGQGLGVLEQFIPLQLDEYGCPRATTVRRRDLELLKQAS 1380
            TIFLGFSGNFKPSWTKLFTSPAGQGLGVLEQFIPLQLDEYGCPRATTVRRRDLELLKQAS
Sbjct: 1321 TIFLGFSGNFKPSWTKLFTSPAGQGLGVLEQFIPLQLDEYGCPRATTVRRRDLELLKQAS 1380

Query: 1381 KAH 1383
            KAH
Sbjct: 1381 KAH 1383


>gi|209447096 transmembrane protein 2 isoform b [Homo sapiens]
          Length = 1320

 Score = 2199 bits (5697), Expect = 0.0
 Identities = 1131/1401 (80%), Positives = 1179/1401 (84%), Gaps = 99/1401 (7%)

Query: 1    MYATDSRGHSPAFLQPQNGNSRHPSGYVPGKVVPLRPPPPPKSQASAKFTSIRREDRATF 60
            MYATDSRGHSPAFLQPQNGNSRHPSGYVPGKVVPLRPPPPPKSQASAKFTSIRREDRATF
Sbjct: 1    MYATDSRGHSPAFLQPQNGNSRHPSGYVPGKVVPLRPPPPPKSQASAKFTSIRREDRATF 60

Query: 61   AFSPEEQQAQRESQKQKRHKNTFICFAITSFSFFIALAIILGISSKYAPDENCPDQNPRL 120
            AFSPEEQQAQRESQKQKRHKNTFICFAITSFSFFIALAIILGISSKYAPDENCPDQNPRL
Sbjct: 61   AFSPEEQQAQRESQKQKRHKNTFICFAITSFSFFIALAIILGISSKYAPDENCPDQNPRL 120

Query: 121  RNWDPGQDSAKQVVIKEGDMLRLTSDATVHSIVIQDGGLLVFGDNKDGSRNITLRTHYIL 180
            RNWDPGQDSAKQVVIKEGDMLRLTSDATVHSIVIQD                        
Sbjct: 121  RNWDPGQDSAKQVVIKEGDMLRLTSDATVHSIVIQD------------------------ 156

Query: 181  IQDGGALHIGAEKCRYKSKATITLYGKSDEGESMPTFGKKFIGVEAGGTLELHGAR---- 236
               GG L                ++G + +G    T    +I ++ GG L +   +    
Sbjct: 157  ---GGLL----------------VFGDNKDGSRNITLRTHYILIQDGGALHIGAEKCRYK 197

Query: 237  -KASWTLLARTLNSSGLP-FGSYTFEKDFSRGLNVRVIDQDT----AKILESERFDTHEY 290
             KA+ TL  ++     +P FG      +    L +    + +    A+ L S       Y
Sbjct: 198  SKATITLYGKSDEGESMPTFGKKFIGVEAGGTLELHGARKASWTLLARTLNSSGLPFGSY 257

Query: 291  RNESRRLQEFLRFQDPGRIVAIAVGDSAAKSLLQGTIQMIQERLGSELIQG-LGYRQAWA 349
              E    ++F R    G  V + +    AK L        + R  S  +Q  L ++    
Sbjct: 258  TFE----KDFSR----GLNVRV-IDQDTAKILESERFDTHEYRNESRRLQEFLRFQDPGR 308

Query: 350  LVGVIDGGSTSCNESVRNYENHSSGGKALAQREFYTVDGQKFSVTAYSEWIEGVSLSGFR 409
            +V +  G S +               K+L Q        Q       SE I+G+   G+R
Sbjct: 309  IVAIAVGDSAA---------------KSLLQGTI-----QMIQERLGSELIQGL---GYR 345

Query: 410  -----VEVVDGVKLNLLDDVSSWKPGDQ--IVVASTDYSMYQAEEFTLLPCSECSHFQVK 462
                 V V+DG   +  + V +++        +A  ++     ++F++   SE       
Sbjct: 346  QAWALVGVIDGGSTSCNESVRNYENHSSGGKALAQREFYTVDGQKFSVTAYSEW------ 399

Query: 463  VKETPQFLHMGEIIDGVDMRAEVGILTRNIVIQGEVEDSCYAENQCQFFDYDTFGGHIMI 522
            ++ETPQFLHMGEIIDGVDMRAEVGILTRNIVIQGEVEDSCYAENQCQFFDYDTFGGHIMI
Sbjct: 400  IEETPQFLHMGEIIDGVDMRAEVGILTRNIVIQGEVEDSCYAENQCQFFDYDTFGGHIMI 459

Query: 523  MKNFTSVHLSYVELKHMGQQQMGRYPVHFHLCGDVDYKGGYRHATFVDGLSIHHSFSRCI 582
            MKNFTSVHLSYVELKHMGQQQMGRYPVHFHLCGDVDYKGGYRHATFVDGLSIHHSFSRCI
Sbjct: 460  MKNFTSVHLSYVELKHMGQQQMGRYPVHFHLCGDVDYKGGYRHATFVDGLSIHHSFSRCI 519

Query: 583  TVHGTNGLLIKDTIGFDTLGHCFFLEDGIEQRNTLFHNLGLLTKPGTLLPTDRNNSMCTT 642
            TVHGTNGLLIKDTIGFDTLGHCFFLEDGIEQRNTLFHNLGLLTKPGTLLPTDRNNSMCTT
Sbjct: 520  TVHGTNGLLIKDTIGFDTLGHCFFLEDGIEQRNTLFHNLGLLTKPGTLLPTDRNNSMCTT 579

Query: 643  MRDKVFGNYIPVPATDCMAVSTFWIAHPNNNLINNAAAGSQDAGIWYLFHKEPTGESSGL 702
            MRDKVFGNYIPVPATDCMAVSTFWIAHPNNNLINNAAAGSQDAGIWYLFHKEPTGESSGL
Sbjct: 580  MRDKVFGNYIPVPATDCMAVSTFWIAHPNNNLINNAAAGSQDAGIWYLFHKEPTGESSGL 639

Query: 703  QLLAKPELTPLGIFYNNRVHSNFKAGLFIDKGVKTTNSSAADPREYLCLDNSARFRPHQD 762
            QLLAKPELTPLGIFYNNRVHSNFKAGLFIDKGVKTTNSSAADPREYLCLDNSARFRPHQD
Sbjct: 640  QLLAKPELTPLGIFYNNRVHSNFKAGLFIDKGVKTTNSSAADPREYLCLDNSARFRPHQD 699

Query: 763  ANPEKPRVAALIDRLIAFKNNDNGAWVRGGDIIVQNSAFADNGIGLTFASDGSFPSDEGS 822
            ANPEKPRVAALIDRLIAFKNNDNGAWVRGGDIIVQNSAFADNGIGLTFASDGSFPSDEGS
Sbjct: 700  ANPEKPRVAALIDRLIAFKNNDNGAWVRGGDIIVQNSAFADNGIGLTFASDGSFPSDEGS 759

Query: 823  SQEVSESLFVGESRNYGFQGGQNKYVGTGGIDQKPRTLPRNRTFPIRGFQIYDGPIHLTR 882
            SQEVSESLFVGESRNYGFQGGQNKYVGTGGIDQKPRTLPRNRTFPIRGFQIYDGPIHLTR
Sbjct: 760  SQEVSESLFVGESRNYGFQGGQNKYVGTGGIDQKPRTLPRNRTFPIRGFQIYDGPIHLTR 819

Query: 883  STFKKYVPTPDRYSSAIGFLMKNSWQITPRNNISLVKFGPHVSLNVFFGKPGPWFEDCEM 942
            STFKKYVPTPDRYSSAIGFLMKNSWQITPRNNISLVKFGPHVSLNVFFGKPGPWFEDCEM
Sbjct: 820  STFKKYVPTPDRYSSAIGFLMKNSWQITPRNNISLVKFGPHVSLNVFFGKPGPWFEDCEM 879

Query: 943  DGDKNSIFHDIDGSVTGYKDAYVGRMDNYLIRHPSCVNVSKWNAVICSGTYAQVYVQTWS 1002
            DGDKNSIFHDIDGSVTGYKDAYVGRMDNYLIRHPSCVNVSKWNAVICSGTYAQVYVQTWS
Sbjct: 880  DGDKNSIFHDIDGSVTGYKDAYVGRMDNYLIRHPSCVNVSKWNAVICSGTYAQVYVQTWS 939

Query: 1003 TQNLSMTITRDEYPSNPMVLRGINQKAAFPQYQPVVMLEKGYTIHWNGPAPRTTFLYLVN 1062
            TQNLSMTITRDEYPSNPMVLRGINQKAAFPQYQPVVMLEKGYTIHWNGPAPRTTFLYLVN
Sbjct: 940  TQNLSMTITRDEYPSNPMVLRGINQKAAFPQYQPVVMLEKGYTIHWNGPAPRTTFLYLVN 999

Query: 1063 FNKNDWIRVGLCYPSNTSFQVTFGYLQRQNGSLSKIEEYEPVHSLEELQRKQSERKFYFD 1122
            FNKNDWIRVGLCYPSNTSFQVTFGYLQRQNGSLSKIEEYEPVHSLEELQRKQSERKFYFD
Sbjct: 1000 FNKNDWIRVGLCYPSNTSFQVTFGYLQRQNGSLSKIEEYEPVHSLEELQRKQSERKFYFD 1059

Query: 1123 SSTGLLFLYLKAKSHRHGHSYCSSQGCERVKIQAATDSKDISNCMAKAYPQYYRKPSVVK 1182
            SSTGLLFLYLKAKSHRHGHSYCSSQGCERVKIQAATDSKDISNCMAKAYPQYYRKPSVVK
Sbjct: 1060 SSTGLLFLYLKAKSHRHGHSYCSSQGCERVKIQAATDSKDISNCMAKAYPQYYRKPSVVK 1119

Query: 1183 RMPAMLTGLCQGCGTRQVVFTSDPHKSYLPVQFQSPDKAETQRGDPSVISVNGTDFTFRS 1242
            RMPAMLTGLCQGCGTRQVVFTSDPHKSYLPVQFQSPDKAETQRGDPSVISVNGTDFTFRS
Sbjct: 1120 RMPAMLTGLCQGCGTRQVVFTSDPHKSYLPVQFQSPDKAETQRGDPSVISVNGTDFTFRS 1179

Query: 1243 AGVLLLVVDPCSVPFRLTEKTVFPLADVSRIEEYLKTGIPPRSIVLLSTRGEIKQLNISH 1302
            AGVLLLVVDPCSVPFRLTEKTVFPLADVSRIEEYLKTGIPPRSIVLLSTRGEIKQLNISH
Sbjct: 1180 AGVLLLVVDPCSVPFRLTEKTVFPLADVSRIEEYLKTGIPPRSIVLLSTRGEIKQLNISH 1239

Query: 1303 LLVPLGLAKPAHLYDKGSTIFLGFSGNFKPSWTKLFTSPAGQGLGVLEQFIPLQLDEYGC 1362
            LLVPLGLAKPAHLYDKGSTIFLGFSGNFKPSWTKLFTSPAGQGLGVLEQFIPLQLDEYGC
Sbjct: 1240 LLVPLGLAKPAHLYDKGSTIFLGFSGNFKPSWTKLFTSPAGQGLGVLEQFIPLQLDEYGC 1299

Query: 1363 PRATTVRRRDLELLKQASKAH 1383
            PRATTVRRRDLELLKQASKAH
Sbjct: 1300 PRATTVRRRDLELLKQASKAH 1320


>gi|38638698 KIAA1199 [Homo sapiens]
          Length = 1361

 Score =  896 bits (2315), Expect = 0.0
 Identities = 455/939 (48%), Positives = 615/939 (65%), Gaps = 29/939 (3%)

Query: 413  VDGVKLNLLDDVSSWKPGDQIVVASTDYSMYQAEEFTLLPCSECSHFQVKVKETPQFLHM 472
            V+   LNL D+V SWKPGD +V+ASTDYSMYQAEEF +LPC  C+  QVKV   P +LH+
Sbjct: 419  VNSTILNLEDNVQSWKPGDTLVIASTDYSMYQAEEFQVLPCRSCAPNQVKVAGKPMYLHI 478

Query: 473  GEIIDGVDMRAEVGILTRNIVIQGEVEDSCYAENQ--CQFFDYDTFGGHIMIMKNFTSVH 530
            GE IDGVDMRAEVG+L+RNI++ GE+ED CY      C FFD+DTFGGHI     F + H
Sbjct: 479  GEEIDGVDMRAEVGLLSRNIIVMGEMEDKCYPYRNHICNFFDFDTFGGHIKFALGFKAAH 538

Query: 531  LSYVELKHMGQQQMGRYPVHFHLCGDVDYKGGYRHATFVDGLSIHHSFSRCITVHGTNGL 590
            L   ELKHMGQQ +G+YP+HFHL GDVD +GGY   T++  LSIHH+FSRC+TVHG+NGL
Sbjct: 539  LEGTELKHMGQQLVGQYPIHFHLAGDVDERGGYDPPTYIRDLSIHHTFSRCVTVHGSNGL 598

Query: 591  LIKDTIGFDTLGHCFFLEDGIEQRNTLFHNLGLLTKPGTLLPTDRNNSMCTTMRDKVFGN 650
            LIKD +G+++LGHCFF EDG E+RNT  H LGLL K GTLLP+DR++ MC  + +  +  
Sbjct: 599  LIKDVVGYNSLGHCFFTEDGPEERNTFDHCLGLLVKSGTLLPSDRDSKMCKMITEDSYPG 658

Query: 651  YIPVPATDCMAVSTFWIAHPNNNLINNAAAGSQDAGIWYLFHKEPTGESSGLQLLAKPEL 710
            YIP P  DC AVSTFW+A+PNNNLIN AAAGS++ G W++FH  PTG S G+      E 
Sbjct: 659  YIPKPRQDCNAVSTFWMANPNNNLINCAAAGSEETGFWFIFHHVPTGPSVGMYSPGYSEH 718

Query: 711  TPLGIFYNNRVHSNFKAGLFIDKGVKTTNSSAADPREYLCLDNSARFRPHQDANPEKPRV 770
             PLG FYNNR HSN++AG+ ID GVKTT +SA D R +L +  SAR+ PHQDA+P KPR 
Sbjct: 719  IPLGKFYNNRAHSNYRAGMIIDNGVKTTEASAKDKRPFLSI-ISARYSPHQDADPLKPRE 777

Query: 771  AALIDRLIAFKNNDNGAWVRGGDIIVQNSAFADNGIGLTFASDGSFPSDEGSSQEVSESL 830
             A+I   IA+KN D+GAW+RGGD+ + +  FADNGIGLT AS G+FP D+GS QE+  SL
Sbjct: 778  PAIIRHFIAYKNQDHGAWLRGGDVWLDSCRFADNGIGLTLASGGTFPYDDGSKQEIKNSL 837

Query: 831  FVGESRNYGFQGGQNKYVGTGGIDQKPRTLPRNRTFPIRGFQIYDGPIHLTRSTFKKYVP 890
            FVGES N G +   N+  G GG+D   RTLP  + FPIRG Q+YDGPI++   TF+K+V 
Sbjct: 838  FVGESGNVGTEMMDNRIWGPGGLDHSGRTLPIGQNFPIRGIQLYDGPINIQNCTFRKFVA 897

Query: 891  TPDRYSSAIGFLMKNSWQITPRNNISLVKF-GPHVSLNVFFGKPGPWFEDCEMDGDKNSI 949
               R++SA+ F + N+WQ  P NN++ + F    ++  VFFG+PGPWF   +MDGDK S+
Sbjct: 898  LEGRHTSALAFRLNNAWQSCPHNNVTGIAFEDVPITSRVFFGEPGPWFNQLDMDGDKTSV 957

Query: 950  FHDIDGSVTGYKDAYVGRMDNYLIRHPSCVNVSKWNAVICSGTYAQVYVQTWSTQNLSMT 1009
            FHD+DGSV+ Y  +Y+ + DN+L+RHP C+NV  W   ICSG YAQ+Y+Q + T NL M 
Sbjct: 958  FHDVDGSVSEYPGSYLTKNDNWLVRHPDCINVPDWRGAICSGCYAQMYIQAYKTSNLRMK 1017

Query: 1010 ITRDEYPSNPMVLRG-INQKAAFPQYQPVVMLEKGYTIHWNGPAPRTTFLYLVNFNKNDW 1068
            I ++++PS+P+ L G + +   + QYQPVV L+KGYTIHW+  AP    ++L+NFNK DW
Sbjct: 1018 IIKNDFPSHPLYLEGALTRSTHYQQYQPVVTLQKGYTIHWDQTAPAELAIWLINFNKGDW 1077

Query: 1069 IRVGLCYPSNTSFQVTFGYLQRQNGSLSKIEEYEPVHSLEELQRKQSERK-FYFDSSTGL 1127
            IRVGLCYP  T+F +      R     SK   +     ++++++    R  +Y+D  +GL
Sbjct: 1078 IRVGLCYPRGTTFSILSDVHNRLLKQTSKTGVFVRTLQMDKVEQSYPGRSHYYWDEDSGL 1137

Query: 1128 LFLYLKAKSHRHGHSYCSSQGCERVKIQA-ATDSKDISNCMAKAYPQYYRKPSVVKRMPA 1186
            LFL LKA++ R   ++CS +GCER+KI+A    +  +S+C A AYP++  +  V   MP 
Sbjct: 1138 LFLKLKAQNEREKFAFCSMKGCERIKIKALIPKNAGVSDCTATAYPKFTERAVVDVPMPK 1197

Query: 1187 MLTGLCQGCGTRQVVFTSDPHKSYLPVQFQSPDKAETQR-GDPSVISVNGTDFTFRSAGV 1245
             L G          + T D    +L V+ +S  +       D + I V+G  +     G+
Sbjct: 1198 KLFG--------SQLKTKD---HFLEVKMESSKQHFFHLWNDFAYIEVDGKKYPSSEDGI 1246

Query: 1246 LLLVVDPCSVPFRLTEKTVFPLADVSRIE----EYLKTGIPPRSIVLLSTRGE-IKQLNI 1300
             ++V+D      R+   T F  + +  I      Y+ T IP  SIVL++++G  + +   
Sbjct: 1247 QVVVID--GNQGRVVSHTSFRNSILQGIPWQLFNYVAT-IPDNSIVLMASKGRYVSRGPW 1303

Query: 1301 SHLLVPLGLAKPAHLYDKGSTIFLGFSGNFKPSWTKLFT 1339
            + +L  LG  +   L  K    F+GF G+F+P W  L T
Sbjct: 1304 TRVLEKLGADRGLKL--KEQMAFVGFKGSFRPIWVTLDT 1340



 Score =  218 bits (554), Expect = 4e-56
 Identities = 127/326 (38%), Positives = 186/326 (57%), Gaps = 10/326 (3%)

Query: 80  KNTFICFAITSFSFFIALAIILGISSKYAPDENCPDQNPRLRNWDPGQDSAKQVVIKEGD 139
           +  F+  A+ + S+ + L    G +S  A    CPDQ+P L+ W+PG D    V I +G 
Sbjct: 6   RQDFLFKAMLTISW-LTLTCFPGATSTVAA--GCPDQSPELQPWNPGHDQDHHVHIGQGK 62

Query: 140 MLRLTSDATVHSIVIQDGGLLVFGDNKDGSRNITLRTHYILIQDGGALHIGAEKCRYKSK 199
            L LTS ATV+SI I +GG LV    KD    I LRT +ILI +GG LH G+  C ++  
Sbjct: 63  TLLLTSSATVYSIHISEGGKLVI---KDHDEPIVLRTRHILIDNGGELHAGSALCPFQGN 119

Query: 200 ATITLYGKSDEG-ESMPTFGKKFIGVEAGGTLELHGARKASWTLLARTLNSSGLPFGSYT 258
            TI LYG++DEG +  P +G K+IGV  GG LELHG +K SWT L +TL+  G+  G Y 
Sbjct: 120 FTIILYGRADEGIQPDPYYGLKYIGVGKGGALELHGQKKLSWTFLNKTLHPGGMAEGGYF 179

Query: 259 FEKDFS-RGLNVRVIDQDTAKILESERFDTHEYRNESRRLQEFLRFQDPGRIVAIAVGDS 317
           FE+ +  RG+ V VID  +  ++ S+RFDT+  + ES RL ++L     GRI+++AV D 
Sbjct: 180 FERSWGHRGVIVHVIDPKSGTVIHSDRFDTYRSKKESERLVQYLNAVPDGRILSVAVNDE 239

Query: 318 AAKSLLQGTIQMIQERLGSELIQGLGYRQAWALVGVIDGGSTSCNESVRNYENHSSGGKA 377
            +++ L    +    +LGS+    LG+R  W+ + V    S+S  + +  Y  H     A
Sbjct: 240 GSRN-LDDMARKAMTKLGSKHFLHLGFRHPWSFLTVKGNPSSSVEDHI-EYHGHRGSAAA 297

Query: 378 LAQREFYTVDGQKFSVTAYSEWIEGV 403
              + F T  G+ F+V+  SEW++ V
Sbjct: 298 RVFKLFQTEHGEYFNVSLSSEWVQDV 323


>gi|126116589 fibrocystin L [Homo sapiens]
          Length = 4243

 Score =  166 bits (421), Expect = 1e-40
 Identities = 109/350 (31%), Positives = 164/350 (46%), Gaps = 65/350 (18%)

Query: 415  GVKLNLLDDVSSWKPGDQIVVASTDYSMYQAEEFTLLPCS-ECSHFQVKVKETPQFLHMG 473
            G ++ +L +  +WKPGD IV+AST +   Q E   +   S       + +     + H+G
Sbjct: 2309 GERILILQEAVTWKPGDNIVIASTGHRHSQGENEKMTIASVSADGINITLSNPLNYTHLG 2368

Query: 474  EII---DGV--DMRAEVGILTRNIVIQGE---------------------VEDSCYAENQ 507
              +   DG   + RAEVGILTRNI+I+G                         +C     
Sbjct: 2369 ITVTLPDGTLFEARAEVGILTRNILIRGSDNVEWNNKIPACPDGFDTGEFATQTCLQGKF 2428

Query: 508  CQFFDYDTFGGHIMIMK-----NFTSVHLSYVELKHMGQQ-QMGRYPVHFHLCGDVDYKG 561
             +    D FGG +M        N  +  + YVE+ H GQ  ++GRYP+H+HL GD+ +K 
Sbjct: 2429 GEEIGSDQFGGCVMFHAPVPGANMVTGRIEYVEVFHAGQAFRLGRYPIHWHLLGDLQFK- 2487

Query: 562  GYRHATFVDGLSIHHSFSRCITVHGTNGLLIKDTIGFDTLGHCFFLEDGIEQRNTLFHNL 621
                 ++V G +IH +++R +T+H T+ LL++  I +D  G  FF+EDGIE  N L +NL
Sbjct: 2488 -----SYVRGCAIHQAYNRAVTIHNTHHLLVERNIIYDIKGGAFFIEDGIEHGNILQYNL 2542

Query: 622  GLLTKPGTLLPTDRNNSMCTTMRDKVFGNYIPVPATDCMAVSTFWIAHPNNNLINNAAAG 681
             +  +  T L                          D +  + FW+ +PNN + +NA AG
Sbjct: 2543 AVFVQQSTSL------------------------LNDDVTPAAFWVTNPNNTIRHNAVAG 2578

Query: 682  SQDAGIWYLFHKEPTGESSGLQLLAKPELTPLGIFYNNRVHSNFKAGLFI 731
                G WY  +  P G S    +  K    PLG F+NN VHS    G++I
Sbjct: 2579 GTHFGFWYRMNNHPDGPSYDRNICQK--RVPLGEFFNNTVHSQGWFGMWI 2626



 Score = 72.0 bits (175), Expect = 4e-12
 Identities = 59/206 (28%), Positives = 94/206 (45%), Gaps = 32/206 (15%)

Query: 415  GVKLNLLDDVSSWKPGDQIVVASTDYSMYQAEEFTLLPCSECSHFQVKVKETPQFLHMGE 474
            G K+  L D   W+ G++IV+ +T Y  +Q E  +++      H  + + ++  + H  E
Sbjct: 3179 GSKVLSLMDAVDWQEGEEIVITTTSYDFHQTETRSIVKILH-DHKILILNDSLSYTHFAE 3237

Query: 475  II------DGVDMRAEVGILTRNIVIQGEVEDSCYAENQCQFFDYDTFGGHIMI------ 522
                    +   + A+VGIL+RNI I GE             +  D+FG  +++      
Sbjct: 3238 KYHVPGTGESYTLAADVGILSRNIKIVGEDYPG---------WSEDSFGARVLVGSFTEN 3288

Query: 523  MKNFT-SVHLSYVELKHMGQQQMG-----RYPVHFHLCGDVDYKGGYRHATFVDGLSIHH 576
            M  F  +  +S VE  H GQ+        RY V F   G +   G    ++++ G + HH
Sbjct: 3289 MMTFKGNARISNVEFYHSGQEGFRDSTDPRYAVTFLNLGQIQEHG----SSYIRGCAFHH 3344

Query: 577  SFSRCITVHGTNGLLIKDTIGFDTLG 602
             FS  I V GT+GL I D I   T+G
Sbjct: 3345 GFSPAIGVFGTDGLDIDDNIIHFTVG 3370



 Score = 63.5 bits (153), Expect = 1e-09
 Identities = 42/115 (36%), Positives = 60/115 (52%), Gaps = 8/115 (6%)

Query: 133  VVIKEGDMLRLTSDATVHSIVIQDGGLLVFGDNKDGSRNITLRTHYILIQDGGALHIGAE 192
            VVI +G  + L     +  +++  GG L+F +      +I L+   ILI DGG L IG E
Sbjct: 2198 VVITKGQTILLDQSTPILKMLLIQGGTLIFDE-----ADIELQAENILITDGGVLQIGTE 2252

Query: 193  KCRYKSKATITLYGKSDEGESMPTFGKKFIGVEAGGTLELHGAR-KASWTLLART 246
               ++ KA ITL+G     E +P +G K + V   G L+LHG     +WT LA T
Sbjct: 2253 TSPFQHKAVITLHGHLRSPE-LPVYGAKTLAVRE-GILDLHGVPVPVTWTRLAHT 2305



 Score = 35.8 bits (81), Expect = 0.29
 Identities = 27/116 (23%), Positives = 53/116 (45%), Gaps = 12/116 (10%)

Query: 972  LIRHPSCVNVSKWNAVICSGT-YAQVYVQTWS----TQNLS-MTITRDEY------PSNP 1019
            +IR  +C  + +W +  C G  YA + +++      T+ LS + I  + Y      P + 
Sbjct: 3744 IIRDSTCKYLPEWQSYQCFGMEYAMMVIESLDPDTETRRLSPVAIMGNGYVDLINGPQDH 3803

Query: 1020 MVLRGINQKAAFPQYQPVVMLEKGYTIHWNGPAPRTTFLYLVNFNKNDWIRVGLCY 1075
                G   +     +  +V L K Y +++ G +P+   L L+N + N  + VG+ +
Sbjct: 3804 GWCAGYTCQRRLSLFHSIVALNKSYEVYFTGTSPQNLRLMLLNVDHNKAVLVGIFF 3859


>gi|126131104 fibrocystin isoform 2 [Homo sapiens]
          Length = 3396

 Score = 66.2 bits (160), Expect = 2e-10
 Identities = 101/415 (24%), Positives = 160/415 (38%), Gaps = 126/415 (30%)

Query: 411  EVVDGVKLNLLDDVSSWKPGDQIVVASTDYSMYQAEEFTLLPCSECSHFQVKVKETPQFL 470
            ++  G +  +++D   W+P D+IV++S+ Y  ++AE  T+    E     V++ E  +  
Sbjct: 2874 DIASGNERIIVEDAVDWRPHDKIVLSSSSYEPHEAEVLTV---KEVKGHHVRIYERLKHR 2930

Query: 471  HMGEI---IDG--VDMRAEVGILTRNIVIQGEVEDSCYAENQCQFF---DYDTFGGHIMI 522
            H+G +    DG  + + AEVG+LTRNI IQ +V  SC        F     + F G + +
Sbjct: 2931 HIGSVHVTEDGRHIRLAAEVGLLTRNIQIQPDV--SCRGRLFVGSFRKSSREEFSGVLQL 2988

Query: 523  MKNFTSVHLSYVELKHMGQQQMGRYPVHFHLCGDVDYKGGYRHATFVDGLSIHHSFSRCI 582
            +          VE+++ G            L   V++       +++   ++H S    I
Sbjct: 2989 LN---------VEIQNFGSP----------LYSSVEF-SNVSAGSWIISSTLHQSCGGGI 3028

Query: 583  TVHGTNGLLIKDTIGFDTLGHCFFLEDGIEQRNTLFHNL-GLLTKPGTLLPTDRNNSMCT 641
                ++G+L+ D I F T GH   LE    Q  T+ +NL  L+T+P              
Sbjct: 3029 HAAASHGVLLNDNIVFGTAGHGIDLEG---QAYTVTNNLVVLMTQP-------------- 3071

Query: 642  TMRDKVFGNYIPVPATDCMAVSTFWIAH------PNNNLINNAAAGSQDAGIWYLFHKEP 695
                               A ST W+A        + NL  N  AGS+  G     HK  
Sbjct: 3072 -------------------AWSTIWVAGIKVNQVKDINLHGNVVAGSERLGFHIRGHK-- 3110

Query: 696  TGESSGLQLLAKPELTPLGIFYNNRVHSNFKA-GLFIDKGVKTTNSSAADPREYLCLDNS 754
                S  +LL          + +N  HS+     L+ + G                LDN 
Sbjct: 3111 ---CSSCELL----------WSDNVAHSSLHGLHLYKESG----------------LDNC 3141

Query: 755  ARFRPHQDANPEKPRVAALIDRLIAFKNNDNGAWVR-GGDIIVQNSAFADNGIGL 808
             R                 I   +AFKN D GA +     + ++N    DN IGL
Sbjct: 3142 TR-----------------ISGFLAFKNFDYGAMLHVENSVEIENITLVDNTIGL 3179



 Score = 65.5 bits (158), Expect = 3e-10
 Identities = 42/119 (35%), Positives = 63/119 (52%), Gaps = 8/119 (6%)

Query: 119  RLRNWDPGQ--DSAKQVVIKEGDMLRLTSDATVHSIVIQDGGLLVFGDNKDGSRNITLRT 176
            R  +W P +       V ++ G +L L ++ ++ +++   GG L+F         I LR 
Sbjct: 1930 RTHSWFPERLPQDGDNVTVENGQLLLLDTNTSILNLLHIKGGKLIFM----APGPIELRA 1985

Query: 177  HYILIQDGGALHIGAEKCRYKSKATITLYGKSDEGESMPTFGKKFIGVEAGGTLELHGA 235
            H IL+ DGG L IG+E   ++ +A ITLYG S      P +G KF+ V   GTL LHG+
Sbjct: 1986 HAILVSDGGELRIGSEDKPFQGRAQITLYGSSYSTPFFP-YGVKFLAVR-NGTLSLHGS 2042



 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 80/338 (23%), Positives = 138/338 (40%), Gaps = 53/338 (15%)

Query: 421  LDDVSSWKPGDQIVVASTD--YSMYQAEEFTLLPCSECSHFQVK--VKETPQFLHMGEII 476
            L+D   W PGD++V+ S          EE   +   + +   +K  ++ +  F       
Sbjct: 2064 LEDAVDWNPGDEVVIISGTGVKGAKPMEEIVTVETVQDTDLYLKSPLRYSHNFTENWVAG 2123

Query: 477  DGVDMRAEVGILTRNIVIQGEVED-------SCYAEN-------QCQFFDYDTFGGHI-- 520
            +   ++A V +L+R+I IQG + +       SC   N        C +   +   G    
Sbjct: 2124 EHHILKATVALLSRSITIQGNLTNEREKLLVSCQEANAPEGNLQHCLYSMSEKMLGSRDM 2183

Query: 521  ---MIMKNFTSVHLSYVELKHMGQQQMGRYPVHFHLCGDVDYKGGYRHATFVDGLSIHHS 577
               +I+++F     S V+LK +  Q +G+   H HL   +   G  R + F+ G ++ +S
Sbjct: 2184 GARVIVQSFPE-EPSQVQLKGVQFQVLGQ-AFHKHL-SSLTLVGAMRES-FIQGCTVRNS 2239

Query: 578  FSRCITVHGTNGLLIKDTIGFDTLGHCFFLEDGIEQR----NTLFHNLGLLTKPGTLLPT 633
            FSR +++ GT GL +   + ++ LGH   +    E R      +       +  G ++  
Sbjct: 2240 FSRGLSMCGTLGLKVDSNVFYNILGHALLVGTCTEMRYISWEAIHGRKDDWSGHGNII-- 2297

Query: 634  DRNNSMCTTMRDKVFGNYIPVPATDCMAVSTFWIAHPNNNLINNAAAGSQDAGIWYLFHK 693
             RNN +      +   N       + +  S  +I  P N +  N   G   AG  Y FH 
Sbjct: 2298 -RNNVIIQVSGAEGLSN------PEMLTPSGIYICSPTNVIEGNRVCG---AGYGYFFHL 2347

Query: 694  EPTGESSGLQLLAKPELTPLGIFYNNRVHSNFKAGLFI 731
              T ++S   LL+         F  N  HS  + GLF+
Sbjct: 2348 -MTNQTSQAPLLS---------FTQNIAHSCTRYGLFV 2375


>gi|126131102 fibrocystin isoform 1 [Homo sapiens]
          Length = 4074

 Score = 66.2 bits (160), Expect = 2e-10
 Identities = 101/415 (24%), Positives = 160/415 (38%), Gaps = 126/415 (30%)

Query: 411  EVVDGVKLNLLDDVSSWKPGDQIVVASTDYSMYQAEEFTLLPCSECSHFQVKVKETPQFL 470
            ++  G +  +++D   W+P D+IV++S+ Y  ++AE  T+    E     V++ E  +  
Sbjct: 2874 DIASGNERIIVEDAVDWRPHDKIVLSSSSYEPHEAEVLTV---KEVKGHHVRIYERLKHR 2930

Query: 471  HMGEI---IDG--VDMRAEVGILTRNIVIQGEVEDSCYAENQCQFF---DYDTFGGHIMI 522
            H+G +    DG  + + AEVG+LTRNI IQ +V  SC        F     + F G + +
Sbjct: 2931 HIGSVHVTEDGRHIRLAAEVGLLTRNIQIQPDV--SCRGRLFVGSFRKSSREEFSGVLQL 2988

Query: 523  MKNFTSVHLSYVELKHMGQQQMGRYPVHFHLCGDVDYKGGYRHATFVDGLSIHHSFSRCI 582
            +          VE+++ G            L   V++       +++   ++H S    I
Sbjct: 2989 LN---------VEIQNFGSP----------LYSSVEF-SNVSAGSWIISSTLHQSCGGGI 3028

Query: 583  TVHGTNGLLIKDTIGFDTLGHCFFLEDGIEQRNTLFHNL-GLLTKPGTLLPTDRNNSMCT 641
                ++G+L+ D I F T GH   LE    Q  T+ +NL  L+T+P              
Sbjct: 3029 HAAASHGVLLNDNIVFGTAGHGIDLEG---QAYTVTNNLVVLMTQP-------------- 3071

Query: 642  TMRDKVFGNYIPVPATDCMAVSTFWIAH------PNNNLINNAAAGSQDAGIWYLFHKEP 695
                               A ST W+A        + NL  N  AGS+  G     HK  
Sbjct: 3072 -------------------AWSTIWVAGIKVNQVKDINLHGNVVAGSERLGFHIRGHK-- 3110

Query: 696  TGESSGLQLLAKPELTPLGIFYNNRVHSNFKA-GLFIDKGVKTTNSSAADPREYLCLDNS 754
                S  +LL          + +N  HS+     L+ + G                LDN 
Sbjct: 3111 ---CSSCELL----------WSDNVAHSSLHGLHLYKESG----------------LDNC 3141

Query: 755  ARFRPHQDANPEKPRVAALIDRLIAFKNNDNGAWVR-GGDIIVQNSAFADNGIGL 808
             R                 I   +AFKN D GA +     + ++N    DN IGL
Sbjct: 3142 TR-----------------ISGFLAFKNFDYGAMLHVENSVEIENITLVDNTIGL 3179



 Score = 65.5 bits (158), Expect = 3e-10
 Identities = 42/119 (35%), Positives = 63/119 (52%), Gaps = 8/119 (6%)

Query: 119  RLRNWDPGQ--DSAKQVVIKEGDMLRLTSDATVHSIVIQDGGLLVFGDNKDGSRNITLRT 176
            R  +W P +       V ++ G +L L ++ ++ +++   GG L+F         I LR 
Sbjct: 1930 RTHSWFPERLPQDGDNVTVENGQLLLLDTNTSILNLLHIKGGKLIFM----APGPIELRA 1985

Query: 177  HYILIQDGGALHIGAEKCRYKSKATITLYGKSDEGESMPTFGKKFIGVEAGGTLELHGA 235
            H IL+ DGG L IG+E   ++ +A ITLYG S      P +G KF+ V   GTL LHG+
Sbjct: 1986 HAILVSDGGELRIGSEDKPFQGRAQITLYGSSYSTPFFP-YGVKFLAVR-NGTLSLHGS 2042



 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 80/338 (23%), Positives = 138/338 (40%), Gaps = 53/338 (15%)

Query: 421  LDDVSSWKPGDQIVVASTD--YSMYQAEEFTLLPCSECSHFQVK--VKETPQFLHMGEII 476
            L+D   W PGD++V+ S          EE   +   + +   +K  ++ +  F       
Sbjct: 2064 LEDAVDWNPGDEVVIISGTGVKGAKPMEEIVTVETVQDTDLYLKSPLRYSHNFTENWVAG 2123

Query: 477  DGVDMRAEVGILTRNIVIQGEVED-------SCYAEN-------QCQFFDYDTFGGHI-- 520
            +   ++A V +L+R+I IQG + +       SC   N        C +   +   G    
Sbjct: 2124 EHHILKATVALLSRSITIQGNLTNEREKLLVSCQEANAPEGNLQHCLYSMSEKMLGSRDM 2183

Query: 521  ---MIMKNFTSVHLSYVELKHMGQQQMGRYPVHFHLCGDVDYKGGYRHATFVDGLSIHHS 577
               +I+++F     S V+LK +  Q +G+   H HL   +   G  R + F+ G ++ +S
Sbjct: 2184 GARVIVQSFPE-EPSQVQLKGVQFQVLGQ-AFHKHL-SSLTLVGAMRES-FIQGCTVRNS 2239

Query: 578  FSRCITVHGTNGLLIKDTIGFDTLGHCFFLEDGIEQR----NTLFHNLGLLTKPGTLLPT 633
            FSR +++ GT GL +   + ++ LGH   +    E R      +       +  G ++  
Sbjct: 2240 FSRGLSMCGTLGLKVDSNVFYNILGHALLVGTCTEMRYISWEAIHGRKDDWSGHGNII-- 2297

Query: 634  DRNNSMCTTMRDKVFGNYIPVPATDCMAVSTFWIAHPNNNLINNAAAGSQDAGIWYLFHK 693
             RNN +      +   N       + +  S  +I  P N +  N   G   AG  Y FH 
Sbjct: 2298 -RNNVIIQVSGAEGLSN------PEMLTPSGIYICSPTNVIEGNRVCG---AGYGYFFHL 2347

Query: 694  EPTGESSGLQLLAKPELTPLGIFYNNRVHSNFKAGLFI 731
              T ++S   LL+         F  N  HS  + GLF+
Sbjct: 2348 -MTNQTSQAPLLS---------FTQNIAHSCTRYGLFV 2375


>gi|210147552 O-linked mannose
           beta1,2-N-acetylglucosaminyltransferase [Homo sapiens]
          Length = 660

 Score = 49.3 bits (116), Expect = 3e-05
 Identities = 29/92 (31%), Positives = 48/92 (52%), Gaps = 2/92 (2%)

Query: 261 KDFSRGLNVRVIDQDTAKILESERFDTHEYRNESRRLQEFLRFQDPGRIVAIAVGDSAAK 320
           ++  RG++V V++Q T  ++    FDT+   +E   +  FL    PGR++   V D  + 
Sbjct: 125 REQGRGIHVIVLNQATGHVMAKRVFDTYS-PHEDEAMVLFLNMVAPGRVLICTVKDEGSF 183

Query: 321 SLLQGTIQMIQERLGSELIQGLGYRQAWALVG 352
            L + T + +   LGS+    LG+R  WA VG
Sbjct: 184 HL-KDTAKALLRSLGSQAGPALGWRDTWAFVG 214


>gi|20270363 family with sequence similarity 3, member D [Homo
           sapiens]
          Length = 224

 Score = 43.5 bits (101), Expect = 0.001
 Identities = 25/96 (26%), Positives = 47/96 (48%), Gaps = 3/96 (3%)

Query: 260 EKDFSRGLNVRVIDQDTAKILESERFDTHEYRNESRRLQEFLRFQDPGRIVAIAVGDSAA 319
           + +  RGLN+ +++  T  +L  + FD   Y  +   L +FL+    G +V +A  D   
Sbjct: 94  KNNVGRGLNIALVNGTTGAVLGQKAFDM--YSGDVMHLVKFLKEIPGGALVLVASYDDPG 151

Query: 320 KSLLQGTIQMIQERLGSELIQGLGYRQAWALVGVID 355
             +   + ++  + LGS   + LG+R +W  +G  D
Sbjct: 152 TKMNDESRKLFSD-LGSSYAKQLGFRDSWVFIGAKD 186


>gi|13324682 family 3, member A protein [Homo sapiens]
          Length = 230

 Score = 42.4 bits (98), Expect = 0.003
 Identities = 25/88 (28%), Positives = 47/88 (53%), Gaps = 3/88 (3%)

Query: 265 RGLNVRVIDQDTAKILESERFDTHEYRNESRRLQEFLRFQDPGRIVAIAVGDSAAKSLLQ 324
           RGLN+ +++  + +++E+  FD   +  +   L +F+R    G +V +A  D  A  + +
Sbjct: 103 RGLNIALVNGVSGELIEARAFDM--WAGDVNDLLKFIRPLHEGTLVFVASYDDPATKMNE 160

Query: 325 GTIQMIQERLGSELIQGLGYRQAWALVG 352
            T ++  E LGS   + L +R +W  VG
Sbjct: 161 ETRKLFSE-LGSRNAKELAFRDSWVFVG 187


>gi|91807125 family with sequence similarity 3, member C precursor
           [Homo sapiens]
          Length = 227

 Score = 41.6 bits (96), Expect = 0.005
 Identities = 27/93 (29%), Positives = 45/93 (48%), Gaps = 3/93 (3%)

Query: 260 EKDFSRGLNVRVIDQDTAKILESERFDTHEYRNESRRLQEFLRFQDPGRIVAIAVGDSAA 319
           + +  RG+NV + +  T ++L+++ FD   +  +     EFL+    G IV +   D  A
Sbjct: 97  KNNVGRGINVALANGKTGEVLDTKYFDM--WGGDVAPFIEFLKAIQDGTIVLMGTYDDGA 154

Query: 320 KSLLQGTIQMIQERLGSELIQGLGYRQAWALVG 352
             L     ++I + LGS  I  LG+R  W   G
Sbjct: 155 TKLNDEARRLIAD-LGSTSITNLGFRDNWVFCG 186


>gi|7661714 family with sequence similarity 3, member C precursor
           [Homo sapiens]
          Length = 227

 Score = 41.6 bits (96), Expect = 0.005
 Identities = 27/93 (29%), Positives = 45/93 (48%), Gaps = 3/93 (3%)

Query: 260 EKDFSRGLNVRVIDQDTAKILESERFDTHEYRNESRRLQEFLRFQDPGRIVAIAVGDSAA 319
           + +  RG+NV + +  T ++L+++ FD   +  +     EFL+    G IV +   D  A
Sbjct: 97  KNNVGRGINVALANGKTGEVLDTKYFDM--WGGDVAPFIEFLKAIQDGTIVLMGTYDDGA 154

Query: 320 KSLLQGTIQMIQERLGSELIQGLGYRQAWALVG 352
             L     ++I + LGS  I  LG+R  W   G
Sbjct: 155 TKLNDEARRLIAD-LGSTSITNLGFRDNWVFCG 186


>gi|46255032 family with sequence similarity 3, member B isoform b
           [Homo sapiens]
          Length = 187

 Score = 37.4 bits (85), Expect = 0.10
 Identities = 27/109 (24%), Positives = 51/109 (46%), Gaps = 4/109 (3%)

Query: 264 SRGLNVRVIDQDTAKILESERFDTHEYRNESRRLQEFLRFQDPGRIVAIAVGDSAAKSLL 323
           +RG+N+ +++  T  +  +  FD +E  N S  + +F++   P  ++ +   D  +  L 
Sbjct: 58  ARGINIAIVNYVTGNVTATRCFDMYEGDN-SGPMTKFIQSAAPKSLLFMVTYDDGSTRLN 116

Query: 324 QGTIQMIQERLGSELIQGLGYRQAWALVGVIDGGSTSCNESVRNYENHS 372
                 I E LGS+ I+ + +R +W  +     G    +E  R   NHS
Sbjct: 117 NDAKNAI-EALGSKEIRNMKFRSSWVFIAA--KGLELPSEIQREKINHS 162


>gi|46255030 family with sequence similarity 3, member B isoform a
           [Homo sapiens]
          Length = 235

 Score = 37.4 bits (85), Expect = 0.10
 Identities = 27/109 (24%), Positives = 51/109 (46%), Gaps = 4/109 (3%)

Query: 264 SRGLNVRVIDQDTAKILESERFDTHEYRNESRRLQEFLRFQDPGRIVAIAVGDSAAKSLL 323
           +RG+N+ +++  T  +  +  FD +E  N S  + +F++   P  ++ +   D  +  L 
Sbjct: 106 ARGINIAIVNYVTGNVTATRCFDMYEGDN-SGPMTKFIQSAAPKSLLFMVTYDDGSTRLN 164

Query: 324 QGTIQMIQERLGSELIQGLGYRQAWALVGVIDGGSTSCNESVRNYENHS 372
                 I E LGS+ I+ + +R +W  +     G    +E  R   NHS
Sbjct: 165 NDAKNAI-EALGSKEIRNMKFRSSWVFIAA--KGLELPSEIQREKINHS 210


>gi|29294649 dicer1 [Homo sapiens]
          Length = 1922

 Score = 32.3 bits (72), Expect = 3.2
 Identities = 34/132 (25%), Positives = 45/132 (34%), Gaps = 18/132 (13%)

Query: 1219 DKAETQRGDPSVISVNGTDFTFRSAGVLLLVVDP-------------CSVPFRLTEKTVF 1265
            +K+E + G PS      T F F+       V+ P               V   LT  + F
Sbjct: 901  EKSEARIGIPSTKYTKETPFVFKLEDYQDAVIIPRYRNFDQPHRFYVADVYTDLTPLSKF 960

Query: 1266 PLADVSRIEEYLKTGIPPRSIVLLSTRGEIKQLNISHLLVPLGLAKPAHLYDKGSTIFLG 1325
            P  +     EY KT        L  T      L++ H    L L  P HL  KG  + L 
Sbjct: 961  PSPEYETFAEYYKT-----KYNLDLTNLNQPLLDVDHTSSRLNLLTPRHLNQKGKALPLS 1015

Query: 1326 FSGNFKPSWTKL 1337
             +   K  W  L
Sbjct: 1016 SAEKRKAKWESL 1027


>gi|29294651 dicer1 [Homo sapiens]
          Length = 1922

 Score = 32.3 bits (72), Expect = 3.2
 Identities = 34/132 (25%), Positives = 45/132 (34%), Gaps = 18/132 (13%)

Query: 1219 DKAETQRGDPSVISVNGTDFTFRSAGVLLLVVDP-------------CSVPFRLTEKTVF 1265
            +K+E + G PS      T F F+       V+ P               V   LT  + F
Sbjct: 901  EKSEARIGIPSTKYTKETPFVFKLEDYQDAVIIPRYRNFDQPHRFYVADVYTDLTPLSKF 960

Query: 1266 PLADVSRIEEYLKTGIPPRSIVLLSTRGEIKQLNISHLLVPLGLAKPAHLYDKGSTIFLG 1325
            P  +     EY KT        L  T      L++ H    L L  P HL  KG  + L 
Sbjct: 961  PSPEYETFAEYYKT-----KYNLDLTNLNQPLLDVDHTSSRLNLLTPRHLNQKGKALPLS 1015

Query: 1326 FSGNFKPSWTKL 1337
             +   K  W  L
Sbjct: 1016 SAEKRKAKWESL 1027


>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
          Length = 841

 Score = 32.0 bits (71), Expect = 4.2
 Identities = 24/88 (27%), Positives = 36/88 (40%), Gaps = 13/88 (14%)

Query: 6   SRGHSPAFLQPQNGNSRHPSGYVPGKVVPLRPPPPPKSQASA-----KFTSIRREDRATF 60
           SRG +P  + P++      S       VP    PP K +        K    RRE+RA +
Sbjct: 93  SRGPTPPAMGPRDARPPRRSSQPSPTAVPASDSPPTKQEVKKAGERHKLAKERREERAKY 152

Query: 61  AFS--------PEEQQAQRESQKQKRHK 80
             +         E+ +A RE Q Q+R +
Sbjct: 153 LAAKKAVWLEKEEKAKALREKQLQERRR 180


>gi|94400925 synaptonemal complex protein 2-like [Homo sapiens]
          Length = 812

 Score = 31.6 bits (70), Expect = 5.5
 Identities = 45/193 (23%), Positives = 74/193 (38%), Gaps = 29/193 (15%)

Query: 238 ASWTLLARTLNSSGLPFGSYTFEKDFSRGLNVRVI-----------DQDTAKILESERFD 286
           +S + L+ T N       SY+  K      N+R++           ++D AK+L     +
Sbjct: 512 SSTSELSWTSNQKKKSLKSYSSRKKTRTRSNLRILPVFPPSSGSGHEKDQAKLLSPSEKE 571

Query: 287 THEYRNESRRLQEFLRFQDPGRIVAIAVGDSAAKSLLQGTIQMIQERLGSELIQGLGYRQ 346
             E  N +       +FQD      +   DSA K+ LQ    + +       +  L + +
Sbjct: 572 IPEQNNTTSPKTSEQKFQDS--FAFLTAEDSAQKTELQDPHSLSE-------LSSLKHSE 622

Query: 347 AWALVGVIDGGS----TSCNESVRNYENHS--SGGKALAQR---EFYTVDGQKFSVTAYS 397
                 +++  S    TS    +RN E+     G  A +Q+   E     G  FS+T   
Sbjct: 623 DEEKPKIVNQESLTESTSLKHKLRNLEDKDIPEGSFAKSQQSRLEEEVASGSPFSITEER 682

Query: 398 EWIEGVSLSGFRV 410
           E  EG+S S   V
Sbjct: 683 ELPEGISTSSLEV 695


>gi|37537554 hypothetical protein FLJ37538 [Homo sapiens]
          Length = 841

 Score = 31.6 bits (70), Expect = 5.5
 Identities = 18/71 (25%), Positives = 30/71 (42%), Gaps = 5/71 (7%)

Query: 20  NSRHPSGYVPGKVVPLR-----PPPPPKSQASAKFTSIRREDRATFAFSPEEQQAQRESQ 74
           +S+ P+G  P   VP R     PPPPP   A+          R+     P +   Q   +
Sbjct: 362 HSKEPAGSTPAPQVPARERETPPPPPPPPAANLLLLGPSGRARSHSTPLPPQGSGQPRGE 421

Query: 75  KQKRHKNTFIC 85
           ++  + ++ IC
Sbjct: 422 RELPNSHSMIC 432


>gi|62422571 collapsin response mediator protein 1 isoform 1 [Homo
           sapiens]
          Length = 686

 Score = 31.2 bits (69), Expect = 7.2
 Identities = 20/76 (26%), Positives = 33/76 (43%), Gaps = 4/76 (5%)

Query: 826 VSESLFVGESRNYGFQGGQNKYVGTGGIDQK--PRTLPRNRTFPIRGFQ--IYDGPIHLT 881
           +S+   V E  N     G  +++      +    R   RN+ F ++G    +YDGP++  
Sbjct: 561 ISQGKIVFEDGNINVNKGMGRFIPRKAFPEHLYQRVKIRNKVFGLQGVSRGMYDGPVYEV 620

Query: 882 RSTFKKYVPTPDRYSS 897
            +T K   P P   SS
Sbjct: 621 PATPKYATPAPSAKSS 636


>gi|4503051 collapsin response mediator protein 1 isoform 2 [Homo
           sapiens]
          Length = 572

 Score = 31.2 bits (69), Expect = 7.2
 Identities = 20/76 (26%), Positives = 33/76 (43%), Gaps = 4/76 (5%)

Query: 826 VSESLFVGESRNYGFQGGQNKYVGTGGIDQK--PRTLPRNRTFPIRGFQ--IYDGPIHLT 881
           +S+   V E  N     G  +++      +    R   RN+ F ++G    +YDGP++  
Sbjct: 447 ISQGKIVFEDGNINVNKGMGRFIPRKAFPEHLYQRVKIRNKVFGLQGVSRGMYDGPVYEV 506

Query: 882 RSTFKKYVPTPDRYSS 897
            +T K   P P   SS
Sbjct: 507 PATPKYATPAPSAKSS 522


>gi|21493039 A-kinase anchor protein 4 isoform 2 [Homo sapiens]
          Length = 845

 Score = 30.8 bits (68), Expect = 9.4
 Identities = 23/90 (25%), Positives = 40/90 (44%), Gaps = 11/90 (12%)

Query: 316 DSAAKSLLQGTIQMIQERL-----GSELIQG------LGYRQAWALVGVIDGGSTSCNES 364
           DS AK L+   +++IQ  L     G +  +       +GY           GG ++   S
Sbjct: 529 DSLAKDLIVSALKLIQYHLTQQTKGKDTCEEDCPGSTMGYMAQSTQYEKCGGGQSAKALS 588

Query: 365 VRNYENHSSGGKALAQREFYTVDGQKFSVT 394
           V+  E+H + G +  Q+E   +D QK  ++
Sbjct: 589 VKQLESHRAPGPSTCQKENQHLDSQKMDMS 618


>gi|21493037 A-kinase anchor protein 4 isoform 1 [Homo sapiens]
          Length = 854

 Score = 30.8 bits (68), Expect = 9.4
 Identities = 23/90 (25%), Positives = 40/90 (44%), Gaps = 11/90 (12%)

Query: 316 DSAAKSLLQGTIQMIQERL-----GSELIQG------LGYRQAWALVGVIDGGSTSCNES 364
           DS AK L+   +++IQ  L     G +  +       +GY           GG ++   S
Sbjct: 538 DSLAKDLIVSALKLIQYHLTQQTKGKDTCEEDCPGSTMGYMAQSTQYEKCGGGQSAKALS 597

Query: 365 VRNYENHSSGGKALAQREFYTVDGQKFSVT 394
           V+  E+H + G +  Q+E   +D QK  ++
Sbjct: 598 VKQLESHRAPGPSTCQKENQHLDSQKMDMS 627


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.136    0.414 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 55,443,663
Number of Sequences: 37866
Number of extensions: 2629473
Number of successful extensions: 7273
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 7206
Number of HSP's gapped (non-prelim): 44
length of query: 1383
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1268
effective length of database: 13,892,928
effective search space: 17616232704
effective search space used: 17616232704
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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