BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|7019555 transmembrane protein 2 isoform a [Homo sapiens] (1383 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|7019555 transmembrane protein 2 isoform a [Homo sapiens] 2830 0.0 gi|209447096 transmembrane protein 2 isoform b [Homo sapiens] 2199 0.0 gi|38638698 KIAA1199 [Homo sapiens] 896 0.0 gi|126116589 fibrocystin L [Homo sapiens] 166 1e-40 gi|126131104 fibrocystin isoform 2 [Homo sapiens] 66 2e-10 gi|126131102 fibrocystin isoform 1 [Homo sapiens] 66 2e-10 gi|210147552 O-linked mannose beta1,2-N-acetylglucosaminyltransf... 49 3e-05 gi|20270363 family with sequence similarity 3, member D [Homo sa... 44 0.001 gi|13324682 family 3, member A protein [Homo sapiens] 42 0.003 gi|91807125 family with sequence similarity 3, member C precurso... 42 0.005 gi|7661714 family with sequence similarity 3, member C precursor... 42 0.005 gi|46255032 family with sequence similarity 3, member B isoform ... 37 0.10 gi|46255030 family with sequence similarity 3, member B isoform ... 37 0.10 gi|29294649 dicer1 [Homo sapiens] 32 3.2 gi|29294651 dicer1 [Homo sapiens] 32 3.2 gi|78042577 MAP7 domain containing 1 [Homo sapiens] 32 4.2 gi|94400925 synaptonemal complex protein 2-like [Homo sapiens] 32 5.5 gi|37537554 hypothetical protein FLJ37538 [Homo sapiens] 32 5.5 gi|62422571 collapsin response mediator protein 1 isoform 1 [Hom... 31 7.2 gi|4503051 collapsin response mediator protein 1 isoform 2 [Homo... 31 7.2 gi|21493039 A-kinase anchor protein 4 isoform 2 [Homo sapiens] 31 9.4 gi|21493037 A-kinase anchor protein 4 isoform 1 [Homo sapiens] 31 9.4 >gi|7019555 transmembrane protein 2 isoform a [Homo sapiens] Length = 1383 Score = 2830 bits (7337), Expect = 0.0 Identities = 1383/1383 (100%), Positives = 1383/1383 (100%) Query: 1 MYATDSRGHSPAFLQPQNGNSRHPSGYVPGKVVPLRPPPPPKSQASAKFTSIRREDRATF 60 MYATDSRGHSPAFLQPQNGNSRHPSGYVPGKVVPLRPPPPPKSQASAKFTSIRREDRATF Sbjct: 1 MYATDSRGHSPAFLQPQNGNSRHPSGYVPGKVVPLRPPPPPKSQASAKFTSIRREDRATF 60 Query: 61 AFSPEEQQAQRESQKQKRHKNTFICFAITSFSFFIALAIILGISSKYAPDENCPDQNPRL 120 AFSPEEQQAQRESQKQKRHKNTFICFAITSFSFFIALAIILGISSKYAPDENCPDQNPRL Sbjct: 61 AFSPEEQQAQRESQKQKRHKNTFICFAITSFSFFIALAIILGISSKYAPDENCPDQNPRL 120 Query: 121 RNWDPGQDSAKQVVIKEGDMLRLTSDATVHSIVIQDGGLLVFGDNKDGSRNITLRTHYIL 180 RNWDPGQDSAKQVVIKEGDMLRLTSDATVHSIVIQDGGLLVFGDNKDGSRNITLRTHYIL Sbjct: 121 RNWDPGQDSAKQVVIKEGDMLRLTSDATVHSIVIQDGGLLVFGDNKDGSRNITLRTHYIL 180 Query: 181 IQDGGALHIGAEKCRYKSKATITLYGKSDEGESMPTFGKKFIGVEAGGTLELHGARKASW 240 IQDGGALHIGAEKCRYKSKATITLYGKSDEGESMPTFGKKFIGVEAGGTLELHGARKASW Sbjct: 181 IQDGGALHIGAEKCRYKSKATITLYGKSDEGESMPTFGKKFIGVEAGGTLELHGARKASW 240 Query: 241 TLLARTLNSSGLPFGSYTFEKDFSRGLNVRVIDQDTAKILESERFDTHEYRNESRRLQEF 300 TLLARTLNSSGLPFGSYTFEKDFSRGLNVRVIDQDTAKILESERFDTHEYRNESRRLQEF Sbjct: 241 TLLARTLNSSGLPFGSYTFEKDFSRGLNVRVIDQDTAKILESERFDTHEYRNESRRLQEF 300 Query: 301 LRFQDPGRIVAIAVGDSAAKSLLQGTIQMIQERLGSELIQGLGYRQAWALVGVIDGGSTS 360 LRFQDPGRIVAIAVGDSAAKSLLQGTIQMIQERLGSELIQGLGYRQAWALVGVIDGGSTS Sbjct: 301 LRFQDPGRIVAIAVGDSAAKSLLQGTIQMIQERLGSELIQGLGYRQAWALVGVIDGGSTS 360 Query: 361 CNESVRNYENHSSGGKALAQREFYTVDGQKFSVTAYSEWIEGVSLSGFRVEVVDGVKLNL 420 CNESVRNYENHSSGGKALAQREFYTVDGQKFSVTAYSEWIEGVSLSGFRVEVVDGVKLNL Sbjct: 361 CNESVRNYENHSSGGKALAQREFYTVDGQKFSVTAYSEWIEGVSLSGFRVEVVDGVKLNL 420 Query: 421 LDDVSSWKPGDQIVVASTDYSMYQAEEFTLLPCSECSHFQVKVKETPQFLHMGEIIDGVD 480 LDDVSSWKPGDQIVVASTDYSMYQAEEFTLLPCSECSHFQVKVKETPQFLHMGEIIDGVD Sbjct: 421 LDDVSSWKPGDQIVVASTDYSMYQAEEFTLLPCSECSHFQVKVKETPQFLHMGEIIDGVD 480 Query: 481 MRAEVGILTRNIVIQGEVEDSCYAENQCQFFDYDTFGGHIMIMKNFTSVHLSYVELKHMG 540 MRAEVGILTRNIVIQGEVEDSCYAENQCQFFDYDTFGGHIMIMKNFTSVHLSYVELKHMG Sbjct: 481 MRAEVGILTRNIVIQGEVEDSCYAENQCQFFDYDTFGGHIMIMKNFTSVHLSYVELKHMG 540 Query: 541 QQQMGRYPVHFHLCGDVDYKGGYRHATFVDGLSIHHSFSRCITVHGTNGLLIKDTIGFDT 600 QQQMGRYPVHFHLCGDVDYKGGYRHATFVDGLSIHHSFSRCITVHGTNGLLIKDTIGFDT Sbjct: 541 QQQMGRYPVHFHLCGDVDYKGGYRHATFVDGLSIHHSFSRCITVHGTNGLLIKDTIGFDT 600 Query: 601 LGHCFFLEDGIEQRNTLFHNLGLLTKPGTLLPTDRNNSMCTTMRDKVFGNYIPVPATDCM 660 LGHCFFLEDGIEQRNTLFHNLGLLTKPGTLLPTDRNNSMCTTMRDKVFGNYIPVPATDCM Sbjct: 601 LGHCFFLEDGIEQRNTLFHNLGLLTKPGTLLPTDRNNSMCTTMRDKVFGNYIPVPATDCM 660 Query: 661 AVSTFWIAHPNNNLINNAAAGSQDAGIWYLFHKEPTGESSGLQLLAKPELTPLGIFYNNR 720 AVSTFWIAHPNNNLINNAAAGSQDAGIWYLFHKEPTGESSGLQLLAKPELTPLGIFYNNR Sbjct: 661 AVSTFWIAHPNNNLINNAAAGSQDAGIWYLFHKEPTGESSGLQLLAKPELTPLGIFYNNR 720 Query: 721 VHSNFKAGLFIDKGVKTTNSSAADPREYLCLDNSARFRPHQDANPEKPRVAALIDRLIAF 780 VHSNFKAGLFIDKGVKTTNSSAADPREYLCLDNSARFRPHQDANPEKPRVAALIDRLIAF Sbjct: 721 VHSNFKAGLFIDKGVKTTNSSAADPREYLCLDNSARFRPHQDANPEKPRVAALIDRLIAF 780 Query: 781 KNNDNGAWVRGGDIIVQNSAFADNGIGLTFASDGSFPSDEGSSQEVSESLFVGESRNYGF 840 KNNDNGAWVRGGDIIVQNSAFADNGIGLTFASDGSFPSDEGSSQEVSESLFVGESRNYGF Sbjct: 781 KNNDNGAWVRGGDIIVQNSAFADNGIGLTFASDGSFPSDEGSSQEVSESLFVGESRNYGF 840 Query: 841 QGGQNKYVGTGGIDQKPRTLPRNRTFPIRGFQIYDGPIHLTRSTFKKYVPTPDRYSSAIG 900 QGGQNKYVGTGGIDQKPRTLPRNRTFPIRGFQIYDGPIHLTRSTFKKYVPTPDRYSSAIG Sbjct: 841 QGGQNKYVGTGGIDQKPRTLPRNRTFPIRGFQIYDGPIHLTRSTFKKYVPTPDRYSSAIG 900 Query: 901 FLMKNSWQITPRNNISLVKFGPHVSLNVFFGKPGPWFEDCEMDGDKNSIFHDIDGSVTGY 960 FLMKNSWQITPRNNISLVKFGPHVSLNVFFGKPGPWFEDCEMDGDKNSIFHDIDGSVTGY Sbjct: 901 FLMKNSWQITPRNNISLVKFGPHVSLNVFFGKPGPWFEDCEMDGDKNSIFHDIDGSVTGY 960 Query: 961 KDAYVGRMDNYLIRHPSCVNVSKWNAVICSGTYAQVYVQTWSTQNLSMTITRDEYPSNPM 1020 KDAYVGRMDNYLIRHPSCVNVSKWNAVICSGTYAQVYVQTWSTQNLSMTITRDEYPSNPM Sbjct: 961 KDAYVGRMDNYLIRHPSCVNVSKWNAVICSGTYAQVYVQTWSTQNLSMTITRDEYPSNPM 1020 Query: 1021 VLRGINQKAAFPQYQPVVMLEKGYTIHWNGPAPRTTFLYLVNFNKNDWIRVGLCYPSNTS 1080 VLRGINQKAAFPQYQPVVMLEKGYTIHWNGPAPRTTFLYLVNFNKNDWIRVGLCYPSNTS Sbjct: 1021 VLRGINQKAAFPQYQPVVMLEKGYTIHWNGPAPRTTFLYLVNFNKNDWIRVGLCYPSNTS 1080 Query: 1081 FQVTFGYLQRQNGSLSKIEEYEPVHSLEELQRKQSERKFYFDSSTGLLFLYLKAKSHRHG 1140 FQVTFGYLQRQNGSLSKIEEYEPVHSLEELQRKQSERKFYFDSSTGLLFLYLKAKSHRHG Sbjct: 1081 FQVTFGYLQRQNGSLSKIEEYEPVHSLEELQRKQSERKFYFDSSTGLLFLYLKAKSHRHG 1140 Query: 1141 HSYCSSQGCERVKIQAATDSKDISNCMAKAYPQYYRKPSVVKRMPAMLTGLCQGCGTRQV 1200 HSYCSSQGCERVKIQAATDSKDISNCMAKAYPQYYRKPSVVKRMPAMLTGLCQGCGTRQV Sbjct: 1141 HSYCSSQGCERVKIQAATDSKDISNCMAKAYPQYYRKPSVVKRMPAMLTGLCQGCGTRQV 1200 Query: 1201 VFTSDPHKSYLPVQFQSPDKAETQRGDPSVISVNGTDFTFRSAGVLLLVVDPCSVPFRLT 1260 VFTSDPHKSYLPVQFQSPDKAETQRGDPSVISVNGTDFTFRSAGVLLLVVDPCSVPFRLT Sbjct: 1201 VFTSDPHKSYLPVQFQSPDKAETQRGDPSVISVNGTDFTFRSAGVLLLVVDPCSVPFRLT 1260 Query: 1261 EKTVFPLADVSRIEEYLKTGIPPRSIVLLSTRGEIKQLNISHLLVPLGLAKPAHLYDKGS 1320 EKTVFPLADVSRIEEYLKTGIPPRSIVLLSTRGEIKQLNISHLLVPLGLAKPAHLYDKGS Sbjct: 1261 EKTVFPLADVSRIEEYLKTGIPPRSIVLLSTRGEIKQLNISHLLVPLGLAKPAHLYDKGS 1320 Query: 1321 TIFLGFSGNFKPSWTKLFTSPAGQGLGVLEQFIPLQLDEYGCPRATTVRRRDLELLKQAS 1380 TIFLGFSGNFKPSWTKLFTSPAGQGLGVLEQFIPLQLDEYGCPRATTVRRRDLELLKQAS Sbjct: 1321 TIFLGFSGNFKPSWTKLFTSPAGQGLGVLEQFIPLQLDEYGCPRATTVRRRDLELLKQAS 1380 Query: 1381 KAH 1383 KAH Sbjct: 1381 KAH 1383 >gi|209447096 transmembrane protein 2 isoform b [Homo sapiens] Length = 1320 Score = 2199 bits (5697), Expect = 0.0 Identities = 1131/1401 (80%), Positives = 1179/1401 (84%), Gaps = 99/1401 (7%) Query: 1 MYATDSRGHSPAFLQPQNGNSRHPSGYVPGKVVPLRPPPPPKSQASAKFTSIRREDRATF 60 MYATDSRGHSPAFLQPQNGNSRHPSGYVPGKVVPLRPPPPPKSQASAKFTSIRREDRATF Sbjct: 1 MYATDSRGHSPAFLQPQNGNSRHPSGYVPGKVVPLRPPPPPKSQASAKFTSIRREDRATF 60 Query: 61 AFSPEEQQAQRESQKQKRHKNTFICFAITSFSFFIALAIILGISSKYAPDENCPDQNPRL 120 AFSPEEQQAQRESQKQKRHKNTFICFAITSFSFFIALAIILGISSKYAPDENCPDQNPRL Sbjct: 61 AFSPEEQQAQRESQKQKRHKNTFICFAITSFSFFIALAIILGISSKYAPDENCPDQNPRL 120 Query: 121 RNWDPGQDSAKQVVIKEGDMLRLTSDATVHSIVIQDGGLLVFGDNKDGSRNITLRTHYIL 180 RNWDPGQDSAKQVVIKEGDMLRLTSDATVHSIVIQD Sbjct: 121 RNWDPGQDSAKQVVIKEGDMLRLTSDATVHSIVIQD------------------------ 156 Query: 181 IQDGGALHIGAEKCRYKSKATITLYGKSDEGESMPTFGKKFIGVEAGGTLELHGAR---- 236 GG L ++G + +G T +I ++ GG L + + Sbjct: 157 ---GGLL----------------VFGDNKDGSRNITLRTHYILIQDGGALHIGAEKCRYK 197 Query: 237 -KASWTLLARTLNSSGLP-FGSYTFEKDFSRGLNVRVIDQDT----AKILESERFDTHEY 290 KA+ TL ++ +P FG + L + + + A+ L S Y Sbjct: 198 SKATITLYGKSDEGESMPTFGKKFIGVEAGGTLELHGARKASWTLLARTLNSSGLPFGSY 257 Query: 291 RNESRRLQEFLRFQDPGRIVAIAVGDSAAKSLLQGTIQMIQERLGSELIQG-LGYRQAWA 349 E ++F R G V + + AK L + R S +Q L ++ Sbjct: 258 TFE----KDFSR----GLNVRV-IDQDTAKILESERFDTHEYRNESRRLQEFLRFQDPGR 308 Query: 350 LVGVIDGGSTSCNESVRNYENHSSGGKALAQREFYTVDGQKFSVTAYSEWIEGVSLSGFR 409 +V + G S + K+L Q Q SE I+G+ G+R Sbjct: 309 IVAIAVGDSAA---------------KSLLQGTI-----QMIQERLGSELIQGL---GYR 345 Query: 410 -----VEVVDGVKLNLLDDVSSWKPGDQ--IVVASTDYSMYQAEEFTLLPCSECSHFQVK 462 V V+DG + + V +++ +A ++ ++F++ SE Sbjct: 346 QAWALVGVIDGGSTSCNESVRNYENHSSGGKALAQREFYTVDGQKFSVTAYSEW------ 399 Query: 463 VKETPQFLHMGEIIDGVDMRAEVGILTRNIVIQGEVEDSCYAENQCQFFDYDTFGGHIMI 522 ++ETPQFLHMGEIIDGVDMRAEVGILTRNIVIQGEVEDSCYAENQCQFFDYDTFGGHIMI Sbjct: 400 IEETPQFLHMGEIIDGVDMRAEVGILTRNIVIQGEVEDSCYAENQCQFFDYDTFGGHIMI 459 Query: 523 MKNFTSVHLSYVELKHMGQQQMGRYPVHFHLCGDVDYKGGYRHATFVDGLSIHHSFSRCI 582 MKNFTSVHLSYVELKHMGQQQMGRYPVHFHLCGDVDYKGGYRHATFVDGLSIHHSFSRCI Sbjct: 460 MKNFTSVHLSYVELKHMGQQQMGRYPVHFHLCGDVDYKGGYRHATFVDGLSIHHSFSRCI 519 Query: 583 TVHGTNGLLIKDTIGFDTLGHCFFLEDGIEQRNTLFHNLGLLTKPGTLLPTDRNNSMCTT 642 TVHGTNGLLIKDTIGFDTLGHCFFLEDGIEQRNTLFHNLGLLTKPGTLLPTDRNNSMCTT Sbjct: 520 TVHGTNGLLIKDTIGFDTLGHCFFLEDGIEQRNTLFHNLGLLTKPGTLLPTDRNNSMCTT 579 Query: 643 MRDKVFGNYIPVPATDCMAVSTFWIAHPNNNLINNAAAGSQDAGIWYLFHKEPTGESSGL 702 MRDKVFGNYIPVPATDCMAVSTFWIAHPNNNLINNAAAGSQDAGIWYLFHKEPTGESSGL Sbjct: 580 MRDKVFGNYIPVPATDCMAVSTFWIAHPNNNLINNAAAGSQDAGIWYLFHKEPTGESSGL 639 Query: 703 QLLAKPELTPLGIFYNNRVHSNFKAGLFIDKGVKTTNSSAADPREYLCLDNSARFRPHQD 762 QLLAKPELTPLGIFYNNRVHSNFKAGLFIDKGVKTTNSSAADPREYLCLDNSARFRPHQD Sbjct: 640 QLLAKPELTPLGIFYNNRVHSNFKAGLFIDKGVKTTNSSAADPREYLCLDNSARFRPHQD 699 Query: 763 ANPEKPRVAALIDRLIAFKNNDNGAWVRGGDIIVQNSAFADNGIGLTFASDGSFPSDEGS 822 ANPEKPRVAALIDRLIAFKNNDNGAWVRGGDIIVQNSAFADNGIGLTFASDGSFPSDEGS Sbjct: 700 ANPEKPRVAALIDRLIAFKNNDNGAWVRGGDIIVQNSAFADNGIGLTFASDGSFPSDEGS 759 Query: 823 SQEVSESLFVGESRNYGFQGGQNKYVGTGGIDQKPRTLPRNRTFPIRGFQIYDGPIHLTR 882 SQEVSESLFVGESRNYGFQGGQNKYVGTGGIDQKPRTLPRNRTFPIRGFQIYDGPIHLTR Sbjct: 760 SQEVSESLFVGESRNYGFQGGQNKYVGTGGIDQKPRTLPRNRTFPIRGFQIYDGPIHLTR 819 Query: 883 STFKKYVPTPDRYSSAIGFLMKNSWQITPRNNISLVKFGPHVSLNVFFGKPGPWFEDCEM 942 STFKKYVPTPDRYSSAIGFLMKNSWQITPRNNISLVKFGPHVSLNVFFGKPGPWFEDCEM Sbjct: 820 STFKKYVPTPDRYSSAIGFLMKNSWQITPRNNISLVKFGPHVSLNVFFGKPGPWFEDCEM 879 Query: 943 DGDKNSIFHDIDGSVTGYKDAYVGRMDNYLIRHPSCVNVSKWNAVICSGTYAQVYVQTWS 1002 DGDKNSIFHDIDGSVTGYKDAYVGRMDNYLIRHPSCVNVSKWNAVICSGTYAQVYVQTWS Sbjct: 880 DGDKNSIFHDIDGSVTGYKDAYVGRMDNYLIRHPSCVNVSKWNAVICSGTYAQVYVQTWS 939 Query: 1003 TQNLSMTITRDEYPSNPMVLRGINQKAAFPQYQPVVMLEKGYTIHWNGPAPRTTFLYLVN 1062 TQNLSMTITRDEYPSNPMVLRGINQKAAFPQYQPVVMLEKGYTIHWNGPAPRTTFLYLVN Sbjct: 940 TQNLSMTITRDEYPSNPMVLRGINQKAAFPQYQPVVMLEKGYTIHWNGPAPRTTFLYLVN 999 Query: 1063 FNKNDWIRVGLCYPSNTSFQVTFGYLQRQNGSLSKIEEYEPVHSLEELQRKQSERKFYFD 1122 FNKNDWIRVGLCYPSNTSFQVTFGYLQRQNGSLSKIEEYEPVHSLEELQRKQSERKFYFD Sbjct: 1000 FNKNDWIRVGLCYPSNTSFQVTFGYLQRQNGSLSKIEEYEPVHSLEELQRKQSERKFYFD 1059 Query: 1123 SSTGLLFLYLKAKSHRHGHSYCSSQGCERVKIQAATDSKDISNCMAKAYPQYYRKPSVVK 1182 SSTGLLFLYLKAKSHRHGHSYCSSQGCERVKIQAATDSKDISNCMAKAYPQYYRKPSVVK Sbjct: 1060 SSTGLLFLYLKAKSHRHGHSYCSSQGCERVKIQAATDSKDISNCMAKAYPQYYRKPSVVK 1119 Query: 1183 RMPAMLTGLCQGCGTRQVVFTSDPHKSYLPVQFQSPDKAETQRGDPSVISVNGTDFTFRS 1242 RMPAMLTGLCQGCGTRQVVFTSDPHKSYLPVQFQSPDKAETQRGDPSVISVNGTDFTFRS Sbjct: 1120 RMPAMLTGLCQGCGTRQVVFTSDPHKSYLPVQFQSPDKAETQRGDPSVISVNGTDFTFRS 1179 Query: 1243 AGVLLLVVDPCSVPFRLTEKTVFPLADVSRIEEYLKTGIPPRSIVLLSTRGEIKQLNISH 1302 AGVLLLVVDPCSVPFRLTEKTVFPLADVSRIEEYLKTGIPPRSIVLLSTRGEIKQLNISH Sbjct: 1180 AGVLLLVVDPCSVPFRLTEKTVFPLADVSRIEEYLKTGIPPRSIVLLSTRGEIKQLNISH 1239 Query: 1303 LLVPLGLAKPAHLYDKGSTIFLGFSGNFKPSWTKLFTSPAGQGLGVLEQFIPLQLDEYGC 1362 LLVPLGLAKPAHLYDKGSTIFLGFSGNFKPSWTKLFTSPAGQGLGVLEQFIPLQLDEYGC Sbjct: 1240 LLVPLGLAKPAHLYDKGSTIFLGFSGNFKPSWTKLFTSPAGQGLGVLEQFIPLQLDEYGC 1299 Query: 1363 PRATTVRRRDLELLKQASKAH 1383 PRATTVRRRDLELLKQASKAH Sbjct: 1300 PRATTVRRRDLELLKQASKAH 1320 >gi|38638698 KIAA1199 [Homo sapiens] Length = 1361 Score = 896 bits (2315), Expect = 0.0 Identities = 455/939 (48%), Positives = 615/939 (65%), Gaps = 29/939 (3%) Query: 413 VDGVKLNLLDDVSSWKPGDQIVVASTDYSMYQAEEFTLLPCSECSHFQVKVKETPQFLHM 472 V+ LNL D+V SWKPGD +V+ASTDYSMYQAEEF +LPC C+ QVKV P +LH+ Sbjct: 419 VNSTILNLEDNVQSWKPGDTLVIASTDYSMYQAEEFQVLPCRSCAPNQVKVAGKPMYLHI 478 Query: 473 GEIIDGVDMRAEVGILTRNIVIQGEVEDSCYAENQ--CQFFDYDTFGGHIMIMKNFTSVH 530 GE IDGVDMRAEVG+L+RNI++ GE+ED CY C FFD+DTFGGHI F + H Sbjct: 479 GEEIDGVDMRAEVGLLSRNIIVMGEMEDKCYPYRNHICNFFDFDTFGGHIKFALGFKAAH 538 Query: 531 LSYVELKHMGQQQMGRYPVHFHLCGDVDYKGGYRHATFVDGLSIHHSFSRCITVHGTNGL 590 L ELKHMGQQ +G+YP+HFHL GDVD +GGY T++ LSIHH+FSRC+TVHG+NGL Sbjct: 539 LEGTELKHMGQQLVGQYPIHFHLAGDVDERGGYDPPTYIRDLSIHHTFSRCVTVHGSNGL 598 Query: 591 LIKDTIGFDTLGHCFFLEDGIEQRNTLFHNLGLLTKPGTLLPTDRNNSMCTTMRDKVFGN 650 LIKD +G+++LGHCFF EDG E+RNT H LGLL K GTLLP+DR++ MC + + + Sbjct: 599 LIKDVVGYNSLGHCFFTEDGPEERNTFDHCLGLLVKSGTLLPSDRDSKMCKMITEDSYPG 658 Query: 651 YIPVPATDCMAVSTFWIAHPNNNLINNAAAGSQDAGIWYLFHKEPTGESSGLQLLAKPEL 710 YIP P DC AVSTFW+A+PNNNLIN AAAGS++ G W++FH PTG S G+ E Sbjct: 659 YIPKPRQDCNAVSTFWMANPNNNLINCAAAGSEETGFWFIFHHVPTGPSVGMYSPGYSEH 718 Query: 711 TPLGIFYNNRVHSNFKAGLFIDKGVKTTNSSAADPREYLCLDNSARFRPHQDANPEKPRV 770 PLG FYNNR HSN++AG+ ID GVKTT +SA D R +L + SAR+ PHQDA+P KPR Sbjct: 719 IPLGKFYNNRAHSNYRAGMIIDNGVKTTEASAKDKRPFLSI-ISARYSPHQDADPLKPRE 777 Query: 771 AALIDRLIAFKNNDNGAWVRGGDIIVQNSAFADNGIGLTFASDGSFPSDEGSSQEVSESL 830 A+I IA+KN D+GAW+RGGD+ + + FADNGIGLT AS G+FP D+GS QE+ SL Sbjct: 778 PAIIRHFIAYKNQDHGAWLRGGDVWLDSCRFADNGIGLTLASGGTFPYDDGSKQEIKNSL 837 Query: 831 FVGESRNYGFQGGQNKYVGTGGIDQKPRTLPRNRTFPIRGFQIYDGPIHLTRSTFKKYVP 890 FVGES N G + N+ G GG+D RTLP + FPIRG Q+YDGPI++ TF+K+V Sbjct: 838 FVGESGNVGTEMMDNRIWGPGGLDHSGRTLPIGQNFPIRGIQLYDGPINIQNCTFRKFVA 897 Query: 891 TPDRYSSAIGFLMKNSWQITPRNNISLVKF-GPHVSLNVFFGKPGPWFEDCEMDGDKNSI 949 R++SA+ F + N+WQ P NN++ + F ++ VFFG+PGPWF +MDGDK S+ Sbjct: 898 LEGRHTSALAFRLNNAWQSCPHNNVTGIAFEDVPITSRVFFGEPGPWFNQLDMDGDKTSV 957 Query: 950 FHDIDGSVTGYKDAYVGRMDNYLIRHPSCVNVSKWNAVICSGTYAQVYVQTWSTQNLSMT 1009 FHD+DGSV+ Y +Y+ + DN+L+RHP C+NV W ICSG YAQ+Y+Q + T NL M Sbjct: 958 FHDVDGSVSEYPGSYLTKNDNWLVRHPDCINVPDWRGAICSGCYAQMYIQAYKTSNLRMK 1017 Query: 1010 ITRDEYPSNPMVLRG-INQKAAFPQYQPVVMLEKGYTIHWNGPAPRTTFLYLVNFNKNDW 1068 I ++++PS+P+ L G + + + QYQPVV L+KGYTIHW+ AP ++L+NFNK DW Sbjct: 1018 IIKNDFPSHPLYLEGALTRSTHYQQYQPVVTLQKGYTIHWDQTAPAELAIWLINFNKGDW 1077 Query: 1069 IRVGLCYPSNTSFQVTFGYLQRQNGSLSKIEEYEPVHSLEELQRKQSERK-FYFDSSTGL 1127 IRVGLCYP T+F + R SK + ++++++ R +Y+D +GL Sbjct: 1078 IRVGLCYPRGTTFSILSDVHNRLLKQTSKTGVFVRTLQMDKVEQSYPGRSHYYWDEDSGL 1137 Query: 1128 LFLYLKAKSHRHGHSYCSSQGCERVKIQA-ATDSKDISNCMAKAYPQYYRKPSVVKRMPA 1186 LFL LKA++ R ++CS +GCER+KI+A + +S+C A AYP++ + V MP Sbjct: 1138 LFLKLKAQNEREKFAFCSMKGCERIKIKALIPKNAGVSDCTATAYPKFTERAVVDVPMPK 1197 Query: 1187 MLTGLCQGCGTRQVVFTSDPHKSYLPVQFQSPDKAETQR-GDPSVISVNGTDFTFRSAGV 1245 L G + T D +L V+ +S + D + I V+G + G+ Sbjct: 1198 KLFG--------SQLKTKD---HFLEVKMESSKQHFFHLWNDFAYIEVDGKKYPSSEDGI 1246 Query: 1246 LLLVVDPCSVPFRLTEKTVFPLADVSRIE----EYLKTGIPPRSIVLLSTRGE-IKQLNI 1300 ++V+D R+ T F + + I Y+ T IP SIVL++++G + + Sbjct: 1247 QVVVID--GNQGRVVSHTSFRNSILQGIPWQLFNYVAT-IPDNSIVLMASKGRYVSRGPW 1303 Query: 1301 SHLLVPLGLAKPAHLYDKGSTIFLGFSGNFKPSWTKLFT 1339 + +L LG + L K F+GF G+F+P W L T Sbjct: 1304 TRVLEKLGADRGLKL--KEQMAFVGFKGSFRPIWVTLDT 1340 Score = 218 bits (554), Expect = 4e-56 Identities = 127/326 (38%), Positives = 186/326 (57%), Gaps = 10/326 (3%) Query: 80 KNTFICFAITSFSFFIALAIILGISSKYAPDENCPDQNPRLRNWDPGQDSAKQVVIKEGD 139 + F+ A+ + S+ + L G +S A CPDQ+P L+ W+PG D V I +G Sbjct: 6 RQDFLFKAMLTISW-LTLTCFPGATSTVAA--GCPDQSPELQPWNPGHDQDHHVHIGQGK 62 Query: 140 MLRLTSDATVHSIVIQDGGLLVFGDNKDGSRNITLRTHYILIQDGGALHIGAEKCRYKSK 199 L LTS ATV+SI I +GG LV KD I LRT +ILI +GG LH G+ C ++ Sbjct: 63 TLLLTSSATVYSIHISEGGKLVI---KDHDEPIVLRTRHILIDNGGELHAGSALCPFQGN 119 Query: 200 ATITLYGKSDEG-ESMPTFGKKFIGVEAGGTLELHGARKASWTLLARTLNSSGLPFGSYT 258 TI LYG++DEG + P +G K+IGV GG LELHG +K SWT L +TL+ G+ G Y Sbjct: 120 FTIILYGRADEGIQPDPYYGLKYIGVGKGGALELHGQKKLSWTFLNKTLHPGGMAEGGYF 179 Query: 259 FEKDFS-RGLNVRVIDQDTAKILESERFDTHEYRNESRRLQEFLRFQDPGRIVAIAVGDS 317 FE+ + RG+ V VID + ++ S+RFDT+ + ES RL ++L GRI+++AV D Sbjct: 180 FERSWGHRGVIVHVIDPKSGTVIHSDRFDTYRSKKESERLVQYLNAVPDGRILSVAVNDE 239 Query: 318 AAKSLLQGTIQMIQERLGSELIQGLGYRQAWALVGVIDGGSTSCNESVRNYENHSSGGKA 377 +++ L + +LGS+ LG+R W+ + V S+S + + Y H A Sbjct: 240 GSRN-LDDMARKAMTKLGSKHFLHLGFRHPWSFLTVKGNPSSSVEDHI-EYHGHRGSAAA 297 Query: 378 LAQREFYTVDGQKFSVTAYSEWIEGV 403 + F T G+ F+V+ SEW++ V Sbjct: 298 RVFKLFQTEHGEYFNVSLSSEWVQDV 323 >gi|126116589 fibrocystin L [Homo sapiens] Length = 4243 Score = 166 bits (421), Expect = 1e-40 Identities = 109/350 (31%), Positives = 164/350 (46%), Gaps = 65/350 (18%) Query: 415 GVKLNLLDDVSSWKPGDQIVVASTDYSMYQAEEFTLLPCS-ECSHFQVKVKETPQFLHMG 473 G ++ +L + +WKPGD IV+AST + Q E + S + + + H+G Sbjct: 2309 GERILILQEAVTWKPGDNIVIASTGHRHSQGENEKMTIASVSADGINITLSNPLNYTHLG 2368 Query: 474 EII---DGV--DMRAEVGILTRNIVIQGE---------------------VEDSCYAENQ 507 + DG + RAEVGILTRNI+I+G +C Sbjct: 2369 ITVTLPDGTLFEARAEVGILTRNILIRGSDNVEWNNKIPACPDGFDTGEFATQTCLQGKF 2428 Query: 508 CQFFDYDTFGGHIMIMK-----NFTSVHLSYVELKHMGQQ-QMGRYPVHFHLCGDVDYKG 561 + D FGG +M N + + YVE+ H GQ ++GRYP+H+HL GD+ +K Sbjct: 2429 GEEIGSDQFGGCVMFHAPVPGANMVTGRIEYVEVFHAGQAFRLGRYPIHWHLLGDLQFK- 2487 Query: 562 GYRHATFVDGLSIHHSFSRCITVHGTNGLLIKDTIGFDTLGHCFFLEDGIEQRNTLFHNL 621 ++V G +IH +++R +T+H T+ LL++ I +D G FF+EDGIE N L +NL Sbjct: 2488 -----SYVRGCAIHQAYNRAVTIHNTHHLLVERNIIYDIKGGAFFIEDGIEHGNILQYNL 2542 Query: 622 GLLTKPGTLLPTDRNNSMCTTMRDKVFGNYIPVPATDCMAVSTFWIAHPNNNLINNAAAG 681 + + T L D + + FW+ +PNN + +NA AG Sbjct: 2543 AVFVQQSTSL------------------------LNDDVTPAAFWVTNPNNTIRHNAVAG 2578 Query: 682 SQDAGIWYLFHKEPTGESSGLQLLAKPELTPLGIFYNNRVHSNFKAGLFI 731 G WY + P G S + K PLG F+NN VHS G++I Sbjct: 2579 GTHFGFWYRMNNHPDGPSYDRNICQK--RVPLGEFFNNTVHSQGWFGMWI 2626 Score = 72.0 bits (175), Expect = 4e-12 Identities = 59/206 (28%), Positives = 94/206 (45%), Gaps = 32/206 (15%) Query: 415 GVKLNLLDDVSSWKPGDQIVVASTDYSMYQAEEFTLLPCSECSHFQVKVKETPQFLHMGE 474 G K+ L D W+ G++IV+ +T Y +Q E +++ H + + ++ + H E Sbjct: 3179 GSKVLSLMDAVDWQEGEEIVITTTSYDFHQTETRSIVKILH-DHKILILNDSLSYTHFAE 3237 Query: 475 II------DGVDMRAEVGILTRNIVIQGEVEDSCYAENQCQFFDYDTFGGHIMI------ 522 + + A+VGIL+RNI I GE + D+FG +++ Sbjct: 3238 KYHVPGTGESYTLAADVGILSRNIKIVGEDYPG---------WSEDSFGARVLVGSFTEN 3288 Query: 523 MKNFT-SVHLSYVELKHMGQQQMG-----RYPVHFHLCGDVDYKGGYRHATFVDGLSIHH 576 M F + +S VE H GQ+ RY V F G + G ++++ G + HH Sbjct: 3289 MMTFKGNARISNVEFYHSGQEGFRDSTDPRYAVTFLNLGQIQEHG----SSYIRGCAFHH 3344 Query: 577 SFSRCITVHGTNGLLIKDTIGFDTLG 602 FS I V GT+GL I D I T+G Sbjct: 3345 GFSPAIGVFGTDGLDIDDNIIHFTVG 3370 Score = 63.5 bits (153), Expect = 1e-09 Identities = 42/115 (36%), Positives = 60/115 (52%), Gaps = 8/115 (6%) Query: 133 VVIKEGDMLRLTSDATVHSIVIQDGGLLVFGDNKDGSRNITLRTHYILIQDGGALHIGAE 192 VVI +G + L + +++ GG L+F + +I L+ ILI DGG L IG E Sbjct: 2198 VVITKGQTILLDQSTPILKMLLIQGGTLIFDE-----ADIELQAENILITDGGVLQIGTE 2252 Query: 193 KCRYKSKATITLYGKSDEGESMPTFGKKFIGVEAGGTLELHGAR-KASWTLLART 246 ++ KA ITL+G E +P +G K + V G L+LHG +WT LA T Sbjct: 2253 TSPFQHKAVITLHGHLRSPE-LPVYGAKTLAVRE-GILDLHGVPVPVTWTRLAHT 2305 Score = 35.8 bits (81), Expect = 0.29 Identities = 27/116 (23%), Positives = 53/116 (45%), Gaps = 12/116 (10%) Query: 972 LIRHPSCVNVSKWNAVICSGT-YAQVYVQTWS----TQNLS-MTITRDEY------PSNP 1019 +IR +C + +W + C G YA + +++ T+ LS + I + Y P + Sbjct: 3744 IIRDSTCKYLPEWQSYQCFGMEYAMMVIESLDPDTETRRLSPVAIMGNGYVDLINGPQDH 3803 Query: 1020 MVLRGINQKAAFPQYQPVVMLEKGYTIHWNGPAPRTTFLYLVNFNKNDWIRVGLCY 1075 G + + +V L K Y +++ G +P+ L L+N + N + VG+ + Sbjct: 3804 GWCAGYTCQRRLSLFHSIVALNKSYEVYFTGTSPQNLRLMLLNVDHNKAVLVGIFF 3859 >gi|126131104 fibrocystin isoform 2 [Homo sapiens] Length = 3396 Score = 66.2 bits (160), Expect = 2e-10 Identities = 101/415 (24%), Positives = 160/415 (38%), Gaps = 126/415 (30%) Query: 411 EVVDGVKLNLLDDVSSWKPGDQIVVASTDYSMYQAEEFTLLPCSECSHFQVKVKETPQFL 470 ++ G + +++D W+P D+IV++S+ Y ++AE T+ E V++ E + Sbjct: 2874 DIASGNERIIVEDAVDWRPHDKIVLSSSSYEPHEAEVLTV---KEVKGHHVRIYERLKHR 2930 Query: 471 HMGEI---IDG--VDMRAEVGILTRNIVIQGEVEDSCYAENQCQFF---DYDTFGGHIMI 522 H+G + DG + + AEVG+LTRNI IQ +V SC F + F G + + Sbjct: 2931 HIGSVHVTEDGRHIRLAAEVGLLTRNIQIQPDV--SCRGRLFVGSFRKSSREEFSGVLQL 2988 Query: 523 MKNFTSVHLSYVELKHMGQQQMGRYPVHFHLCGDVDYKGGYRHATFVDGLSIHHSFSRCI 582 + VE+++ G L V++ +++ ++H S I Sbjct: 2989 LN---------VEIQNFGSP----------LYSSVEF-SNVSAGSWIISSTLHQSCGGGI 3028 Query: 583 TVHGTNGLLIKDTIGFDTLGHCFFLEDGIEQRNTLFHNL-GLLTKPGTLLPTDRNNSMCT 641 ++G+L+ D I F T GH LE Q T+ +NL L+T+P Sbjct: 3029 HAAASHGVLLNDNIVFGTAGHGIDLEG---QAYTVTNNLVVLMTQP-------------- 3071 Query: 642 TMRDKVFGNYIPVPATDCMAVSTFWIAH------PNNNLINNAAAGSQDAGIWYLFHKEP 695 A ST W+A + NL N AGS+ G HK Sbjct: 3072 -------------------AWSTIWVAGIKVNQVKDINLHGNVVAGSERLGFHIRGHK-- 3110 Query: 696 TGESSGLQLLAKPELTPLGIFYNNRVHSNFKA-GLFIDKGVKTTNSSAADPREYLCLDNS 754 S +LL + +N HS+ L+ + G LDN Sbjct: 3111 ---CSSCELL----------WSDNVAHSSLHGLHLYKESG----------------LDNC 3141 Query: 755 ARFRPHQDANPEKPRVAALIDRLIAFKNNDNGAWVR-GGDIIVQNSAFADNGIGL 808 R I +AFKN D GA + + ++N DN IGL Sbjct: 3142 TR-----------------ISGFLAFKNFDYGAMLHVENSVEIENITLVDNTIGL 3179 Score = 65.5 bits (158), Expect = 3e-10 Identities = 42/119 (35%), Positives = 63/119 (52%), Gaps = 8/119 (6%) Query: 119 RLRNWDPGQ--DSAKQVVIKEGDMLRLTSDATVHSIVIQDGGLLVFGDNKDGSRNITLRT 176 R +W P + V ++ G +L L ++ ++ +++ GG L+F I LR Sbjct: 1930 RTHSWFPERLPQDGDNVTVENGQLLLLDTNTSILNLLHIKGGKLIFM----APGPIELRA 1985 Query: 177 HYILIQDGGALHIGAEKCRYKSKATITLYGKSDEGESMPTFGKKFIGVEAGGTLELHGA 235 H IL+ DGG L IG+E ++ +A ITLYG S P +G KF+ V GTL LHG+ Sbjct: 1986 HAILVSDGGELRIGSEDKPFQGRAQITLYGSSYSTPFFP-YGVKFLAVR-NGTLSLHGS 2042 Score = 56.2 bits (134), Expect = 2e-07 Identities = 80/338 (23%), Positives = 138/338 (40%), Gaps = 53/338 (15%) Query: 421 LDDVSSWKPGDQIVVASTD--YSMYQAEEFTLLPCSECSHFQVK--VKETPQFLHMGEII 476 L+D W PGD++V+ S EE + + + +K ++ + F Sbjct: 2064 LEDAVDWNPGDEVVIISGTGVKGAKPMEEIVTVETVQDTDLYLKSPLRYSHNFTENWVAG 2123 Query: 477 DGVDMRAEVGILTRNIVIQGEVED-------SCYAEN-------QCQFFDYDTFGGHI-- 520 + ++A V +L+R+I IQG + + SC N C + + G Sbjct: 2124 EHHILKATVALLSRSITIQGNLTNEREKLLVSCQEANAPEGNLQHCLYSMSEKMLGSRDM 2183 Query: 521 ---MIMKNFTSVHLSYVELKHMGQQQMGRYPVHFHLCGDVDYKGGYRHATFVDGLSIHHS 577 +I+++F S V+LK + Q +G+ H HL + G R + F+ G ++ +S Sbjct: 2184 GARVIVQSFPE-EPSQVQLKGVQFQVLGQ-AFHKHL-SSLTLVGAMRES-FIQGCTVRNS 2239 Query: 578 FSRCITVHGTNGLLIKDTIGFDTLGHCFFLEDGIEQR----NTLFHNLGLLTKPGTLLPT 633 FSR +++ GT GL + + ++ LGH + E R + + G ++ Sbjct: 2240 FSRGLSMCGTLGLKVDSNVFYNILGHALLVGTCTEMRYISWEAIHGRKDDWSGHGNII-- 2297 Query: 634 DRNNSMCTTMRDKVFGNYIPVPATDCMAVSTFWIAHPNNNLINNAAAGSQDAGIWYLFHK 693 RNN + + N + + S +I P N + N G AG Y FH Sbjct: 2298 -RNNVIIQVSGAEGLSN------PEMLTPSGIYICSPTNVIEGNRVCG---AGYGYFFHL 2347 Query: 694 EPTGESSGLQLLAKPELTPLGIFYNNRVHSNFKAGLFI 731 T ++S LL+ F N HS + GLF+ Sbjct: 2348 -MTNQTSQAPLLS---------FTQNIAHSCTRYGLFV 2375 >gi|126131102 fibrocystin isoform 1 [Homo sapiens] Length = 4074 Score = 66.2 bits (160), Expect = 2e-10 Identities = 101/415 (24%), Positives = 160/415 (38%), Gaps = 126/415 (30%) Query: 411 EVVDGVKLNLLDDVSSWKPGDQIVVASTDYSMYQAEEFTLLPCSECSHFQVKVKETPQFL 470 ++ G + +++D W+P D+IV++S+ Y ++AE T+ E V++ E + Sbjct: 2874 DIASGNERIIVEDAVDWRPHDKIVLSSSSYEPHEAEVLTV---KEVKGHHVRIYERLKHR 2930 Query: 471 HMGEI---IDG--VDMRAEVGILTRNIVIQGEVEDSCYAENQCQFF---DYDTFGGHIMI 522 H+G + DG + + AEVG+LTRNI IQ +V SC F + F G + + Sbjct: 2931 HIGSVHVTEDGRHIRLAAEVGLLTRNIQIQPDV--SCRGRLFVGSFRKSSREEFSGVLQL 2988 Query: 523 MKNFTSVHLSYVELKHMGQQQMGRYPVHFHLCGDVDYKGGYRHATFVDGLSIHHSFSRCI 582 + VE+++ G L V++ +++ ++H S I Sbjct: 2989 LN---------VEIQNFGSP----------LYSSVEF-SNVSAGSWIISSTLHQSCGGGI 3028 Query: 583 TVHGTNGLLIKDTIGFDTLGHCFFLEDGIEQRNTLFHNL-GLLTKPGTLLPTDRNNSMCT 641 ++G+L+ D I F T GH LE Q T+ +NL L+T+P Sbjct: 3029 HAAASHGVLLNDNIVFGTAGHGIDLEG---QAYTVTNNLVVLMTQP-------------- 3071 Query: 642 TMRDKVFGNYIPVPATDCMAVSTFWIAH------PNNNLINNAAAGSQDAGIWYLFHKEP 695 A ST W+A + NL N AGS+ G HK Sbjct: 3072 -------------------AWSTIWVAGIKVNQVKDINLHGNVVAGSERLGFHIRGHK-- 3110 Query: 696 TGESSGLQLLAKPELTPLGIFYNNRVHSNFKA-GLFIDKGVKTTNSSAADPREYLCLDNS 754 S +LL + +N HS+ L+ + G LDN Sbjct: 3111 ---CSSCELL----------WSDNVAHSSLHGLHLYKESG----------------LDNC 3141 Query: 755 ARFRPHQDANPEKPRVAALIDRLIAFKNNDNGAWVR-GGDIIVQNSAFADNGIGL 808 R I +AFKN D GA + + ++N DN IGL Sbjct: 3142 TR-----------------ISGFLAFKNFDYGAMLHVENSVEIENITLVDNTIGL 3179 Score = 65.5 bits (158), Expect = 3e-10 Identities = 42/119 (35%), Positives = 63/119 (52%), Gaps = 8/119 (6%) Query: 119 RLRNWDPGQ--DSAKQVVIKEGDMLRLTSDATVHSIVIQDGGLLVFGDNKDGSRNITLRT 176 R +W P + V ++ G +L L ++ ++ +++ GG L+F I LR Sbjct: 1930 RTHSWFPERLPQDGDNVTVENGQLLLLDTNTSILNLLHIKGGKLIFM----APGPIELRA 1985 Query: 177 HYILIQDGGALHIGAEKCRYKSKATITLYGKSDEGESMPTFGKKFIGVEAGGTLELHGA 235 H IL+ DGG L IG+E ++ +A ITLYG S P +G KF+ V GTL LHG+ Sbjct: 1986 HAILVSDGGELRIGSEDKPFQGRAQITLYGSSYSTPFFP-YGVKFLAVR-NGTLSLHGS 2042 Score = 56.2 bits (134), Expect = 2e-07 Identities = 80/338 (23%), Positives = 138/338 (40%), Gaps = 53/338 (15%) Query: 421 LDDVSSWKPGDQIVVASTD--YSMYQAEEFTLLPCSECSHFQVK--VKETPQFLHMGEII 476 L+D W PGD++V+ S EE + + + +K ++ + F Sbjct: 2064 LEDAVDWNPGDEVVIISGTGVKGAKPMEEIVTVETVQDTDLYLKSPLRYSHNFTENWVAG 2123 Query: 477 DGVDMRAEVGILTRNIVIQGEVED-------SCYAEN-------QCQFFDYDTFGGHI-- 520 + ++A V +L+R+I IQG + + SC N C + + G Sbjct: 2124 EHHILKATVALLSRSITIQGNLTNEREKLLVSCQEANAPEGNLQHCLYSMSEKMLGSRDM 2183 Query: 521 ---MIMKNFTSVHLSYVELKHMGQQQMGRYPVHFHLCGDVDYKGGYRHATFVDGLSIHHS 577 +I+++F S V+LK + Q +G+ H HL + G R + F+ G ++ +S Sbjct: 2184 GARVIVQSFPE-EPSQVQLKGVQFQVLGQ-AFHKHL-SSLTLVGAMRES-FIQGCTVRNS 2239 Query: 578 FSRCITVHGTNGLLIKDTIGFDTLGHCFFLEDGIEQR----NTLFHNLGLLTKPGTLLPT 633 FSR +++ GT GL + + ++ LGH + E R + + G ++ Sbjct: 2240 FSRGLSMCGTLGLKVDSNVFYNILGHALLVGTCTEMRYISWEAIHGRKDDWSGHGNII-- 2297 Query: 634 DRNNSMCTTMRDKVFGNYIPVPATDCMAVSTFWIAHPNNNLINNAAAGSQDAGIWYLFHK 693 RNN + + N + + S +I P N + N G AG Y FH Sbjct: 2298 -RNNVIIQVSGAEGLSN------PEMLTPSGIYICSPTNVIEGNRVCG---AGYGYFFHL 2347 Query: 694 EPTGESSGLQLLAKPELTPLGIFYNNRVHSNFKAGLFI 731 T ++S LL+ F N HS + GLF+ Sbjct: 2348 -MTNQTSQAPLLS---------FTQNIAHSCTRYGLFV 2375 >gi|210147552 O-linked mannose beta1,2-N-acetylglucosaminyltransferase [Homo sapiens] Length = 660 Score = 49.3 bits (116), Expect = 3e-05 Identities = 29/92 (31%), Positives = 48/92 (52%), Gaps = 2/92 (2%) Query: 261 KDFSRGLNVRVIDQDTAKILESERFDTHEYRNESRRLQEFLRFQDPGRIVAIAVGDSAAK 320 ++ RG++V V++Q T ++ FDT+ +E + FL PGR++ V D + Sbjct: 125 REQGRGIHVIVLNQATGHVMAKRVFDTYS-PHEDEAMVLFLNMVAPGRVLICTVKDEGSF 183 Query: 321 SLLQGTIQMIQERLGSELIQGLGYRQAWALVG 352 L + T + + LGS+ LG+R WA VG Sbjct: 184 HL-KDTAKALLRSLGSQAGPALGWRDTWAFVG 214 >gi|20270363 family with sequence similarity 3, member D [Homo sapiens] Length = 224 Score = 43.5 bits (101), Expect = 0.001 Identities = 25/96 (26%), Positives = 47/96 (48%), Gaps = 3/96 (3%) Query: 260 EKDFSRGLNVRVIDQDTAKILESERFDTHEYRNESRRLQEFLRFQDPGRIVAIAVGDSAA 319 + + RGLN+ +++ T +L + FD Y + L +FL+ G +V +A D Sbjct: 94 KNNVGRGLNIALVNGTTGAVLGQKAFDM--YSGDVMHLVKFLKEIPGGALVLVASYDDPG 151 Query: 320 KSLLQGTIQMIQERLGSELIQGLGYRQAWALVGVID 355 + + ++ + LGS + LG+R +W +G D Sbjct: 152 TKMNDESRKLFSD-LGSSYAKQLGFRDSWVFIGAKD 186 >gi|13324682 family 3, member A protein [Homo sapiens] Length = 230 Score = 42.4 bits (98), Expect = 0.003 Identities = 25/88 (28%), Positives = 47/88 (53%), Gaps = 3/88 (3%) Query: 265 RGLNVRVIDQDTAKILESERFDTHEYRNESRRLQEFLRFQDPGRIVAIAVGDSAAKSLLQ 324 RGLN+ +++ + +++E+ FD + + L +F+R G +V +A D A + + Sbjct: 103 RGLNIALVNGVSGELIEARAFDM--WAGDVNDLLKFIRPLHEGTLVFVASYDDPATKMNE 160 Query: 325 GTIQMIQERLGSELIQGLGYRQAWALVG 352 T ++ E LGS + L +R +W VG Sbjct: 161 ETRKLFSE-LGSRNAKELAFRDSWVFVG 187 >gi|91807125 family with sequence similarity 3, member C precursor [Homo sapiens] Length = 227 Score = 41.6 bits (96), Expect = 0.005 Identities = 27/93 (29%), Positives = 45/93 (48%), Gaps = 3/93 (3%) Query: 260 EKDFSRGLNVRVIDQDTAKILESERFDTHEYRNESRRLQEFLRFQDPGRIVAIAVGDSAA 319 + + RG+NV + + T ++L+++ FD + + EFL+ G IV + D A Sbjct: 97 KNNVGRGINVALANGKTGEVLDTKYFDM--WGGDVAPFIEFLKAIQDGTIVLMGTYDDGA 154 Query: 320 KSLLQGTIQMIQERLGSELIQGLGYRQAWALVG 352 L ++I + LGS I LG+R W G Sbjct: 155 TKLNDEARRLIAD-LGSTSITNLGFRDNWVFCG 186 >gi|7661714 family with sequence similarity 3, member C precursor [Homo sapiens] Length = 227 Score = 41.6 bits (96), Expect = 0.005 Identities = 27/93 (29%), Positives = 45/93 (48%), Gaps = 3/93 (3%) Query: 260 EKDFSRGLNVRVIDQDTAKILESERFDTHEYRNESRRLQEFLRFQDPGRIVAIAVGDSAA 319 + + RG+NV + + T ++L+++ FD + + EFL+ G IV + D A Sbjct: 97 KNNVGRGINVALANGKTGEVLDTKYFDM--WGGDVAPFIEFLKAIQDGTIVLMGTYDDGA 154 Query: 320 KSLLQGTIQMIQERLGSELIQGLGYRQAWALVG 352 L ++I + LGS I LG+R W G Sbjct: 155 TKLNDEARRLIAD-LGSTSITNLGFRDNWVFCG 186 >gi|46255032 family with sequence similarity 3, member B isoform b [Homo sapiens] Length = 187 Score = 37.4 bits (85), Expect = 0.10 Identities = 27/109 (24%), Positives = 51/109 (46%), Gaps = 4/109 (3%) Query: 264 SRGLNVRVIDQDTAKILESERFDTHEYRNESRRLQEFLRFQDPGRIVAIAVGDSAAKSLL 323 +RG+N+ +++ T + + FD +E N S + +F++ P ++ + D + L Sbjct: 58 ARGINIAIVNYVTGNVTATRCFDMYEGDN-SGPMTKFIQSAAPKSLLFMVTYDDGSTRLN 116 Query: 324 QGTIQMIQERLGSELIQGLGYRQAWALVGVIDGGSTSCNESVRNYENHS 372 I E LGS+ I+ + +R +W + G +E R NHS Sbjct: 117 NDAKNAI-EALGSKEIRNMKFRSSWVFIAA--KGLELPSEIQREKINHS 162 >gi|46255030 family with sequence similarity 3, member B isoform a [Homo sapiens] Length = 235 Score = 37.4 bits (85), Expect = 0.10 Identities = 27/109 (24%), Positives = 51/109 (46%), Gaps = 4/109 (3%) Query: 264 SRGLNVRVIDQDTAKILESERFDTHEYRNESRRLQEFLRFQDPGRIVAIAVGDSAAKSLL 323 +RG+N+ +++ T + + FD +E N S + +F++ P ++ + D + L Sbjct: 106 ARGINIAIVNYVTGNVTATRCFDMYEGDN-SGPMTKFIQSAAPKSLLFMVTYDDGSTRLN 164 Query: 324 QGTIQMIQERLGSELIQGLGYRQAWALVGVIDGGSTSCNESVRNYENHS 372 I E LGS+ I+ + +R +W + G +E R NHS Sbjct: 165 NDAKNAI-EALGSKEIRNMKFRSSWVFIAA--KGLELPSEIQREKINHS 210 >gi|29294649 dicer1 [Homo sapiens] Length = 1922 Score = 32.3 bits (72), Expect = 3.2 Identities = 34/132 (25%), Positives = 45/132 (34%), Gaps = 18/132 (13%) Query: 1219 DKAETQRGDPSVISVNGTDFTFRSAGVLLLVVDP-------------CSVPFRLTEKTVF 1265 +K+E + G PS T F F+ V+ P V LT + F Sbjct: 901 EKSEARIGIPSTKYTKETPFVFKLEDYQDAVIIPRYRNFDQPHRFYVADVYTDLTPLSKF 960 Query: 1266 PLADVSRIEEYLKTGIPPRSIVLLSTRGEIKQLNISHLLVPLGLAKPAHLYDKGSTIFLG 1325 P + EY KT L T L++ H L L P HL KG + L Sbjct: 961 PSPEYETFAEYYKT-----KYNLDLTNLNQPLLDVDHTSSRLNLLTPRHLNQKGKALPLS 1015 Query: 1326 FSGNFKPSWTKL 1337 + K W L Sbjct: 1016 SAEKRKAKWESL 1027 >gi|29294651 dicer1 [Homo sapiens] Length = 1922 Score = 32.3 bits (72), Expect = 3.2 Identities = 34/132 (25%), Positives = 45/132 (34%), Gaps = 18/132 (13%) Query: 1219 DKAETQRGDPSVISVNGTDFTFRSAGVLLLVVDP-------------CSVPFRLTEKTVF 1265 +K+E + G PS T F F+ V+ P V LT + F Sbjct: 901 EKSEARIGIPSTKYTKETPFVFKLEDYQDAVIIPRYRNFDQPHRFYVADVYTDLTPLSKF 960 Query: 1266 PLADVSRIEEYLKTGIPPRSIVLLSTRGEIKQLNISHLLVPLGLAKPAHLYDKGSTIFLG 1325 P + EY KT L T L++ H L L P HL KG + L Sbjct: 961 PSPEYETFAEYYKT-----KYNLDLTNLNQPLLDVDHTSSRLNLLTPRHLNQKGKALPLS 1015 Query: 1326 FSGNFKPSWTKL 1337 + K W L Sbjct: 1016 SAEKRKAKWESL 1027 >gi|78042577 MAP7 domain containing 1 [Homo sapiens] Length = 841 Score = 32.0 bits (71), Expect = 4.2 Identities = 24/88 (27%), Positives = 36/88 (40%), Gaps = 13/88 (14%) Query: 6 SRGHSPAFLQPQNGNSRHPSGYVPGKVVPLRPPPPPKSQASA-----KFTSIRREDRATF 60 SRG +P + P++ S VP PP K + K RRE+RA + Sbjct: 93 SRGPTPPAMGPRDARPPRRSSQPSPTAVPASDSPPTKQEVKKAGERHKLAKERREERAKY 152 Query: 61 AFS--------PEEQQAQRESQKQKRHK 80 + E+ +A RE Q Q+R + Sbjct: 153 LAAKKAVWLEKEEKAKALREKQLQERRR 180 >gi|94400925 synaptonemal complex protein 2-like [Homo sapiens] Length = 812 Score = 31.6 bits (70), Expect = 5.5 Identities = 45/193 (23%), Positives = 74/193 (38%), Gaps = 29/193 (15%) Query: 238 ASWTLLARTLNSSGLPFGSYTFEKDFSRGLNVRVI-----------DQDTAKILESERFD 286 +S + L+ T N SY+ K N+R++ ++D AK+L + Sbjct: 512 SSTSELSWTSNQKKKSLKSYSSRKKTRTRSNLRILPVFPPSSGSGHEKDQAKLLSPSEKE 571 Query: 287 THEYRNESRRLQEFLRFQDPGRIVAIAVGDSAAKSLLQGTIQMIQERLGSELIQGLGYRQ 346 E N + +FQD + DSA K+ LQ + + + L + + Sbjct: 572 IPEQNNTTSPKTSEQKFQDS--FAFLTAEDSAQKTELQDPHSLSE-------LSSLKHSE 622 Query: 347 AWALVGVIDGGS----TSCNESVRNYENHS--SGGKALAQR---EFYTVDGQKFSVTAYS 397 +++ S TS +RN E+ G A +Q+ E G FS+T Sbjct: 623 DEEKPKIVNQESLTESTSLKHKLRNLEDKDIPEGSFAKSQQSRLEEEVASGSPFSITEER 682 Query: 398 EWIEGVSLSGFRV 410 E EG+S S V Sbjct: 683 ELPEGISTSSLEV 695 >gi|37537554 hypothetical protein FLJ37538 [Homo sapiens] Length = 841 Score = 31.6 bits (70), Expect = 5.5 Identities = 18/71 (25%), Positives = 30/71 (42%), Gaps = 5/71 (7%) Query: 20 NSRHPSGYVPGKVVPLR-----PPPPPKSQASAKFTSIRREDRATFAFSPEEQQAQRESQ 74 +S+ P+G P VP R PPPPP A+ R+ P + Q + Sbjct: 362 HSKEPAGSTPAPQVPARERETPPPPPPPPAANLLLLGPSGRARSHSTPLPPQGSGQPRGE 421 Query: 75 KQKRHKNTFIC 85 ++ + ++ IC Sbjct: 422 RELPNSHSMIC 432 >gi|62422571 collapsin response mediator protein 1 isoform 1 [Homo sapiens] Length = 686 Score = 31.2 bits (69), Expect = 7.2 Identities = 20/76 (26%), Positives = 33/76 (43%), Gaps = 4/76 (5%) Query: 826 VSESLFVGESRNYGFQGGQNKYVGTGGIDQK--PRTLPRNRTFPIRGFQ--IYDGPIHLT 881 +S+ V E N G +++ + R RN+ F ++G +YDGP++ Sbjct: 561 ISQGKIVFEDGNINVNKGMGRFIPRKAFPEHLYQRVKIRNKVFGLQGVSRGMYDGPVYEV 620 Query: 882 RSTFKKYVPTPDRYSS 897 +T K P P SS Sbjct: 621 PATPKYATPAPSAKSS 636 >gi|4503051 collapsin response mediator protein 1 isoform 2 [Homo sapiens] Length = 572 Score = 31.2 bits (69), Expect = 7.2 Identities = 20/76 (26%), Positives = 33/76 (43%), Gaps = 4/76 (5%) Query: 826 VSESLFVGESRNYGFQGGQNKYVGTGGIDQK--PRTLPRNRTFPIRGFQ--IYDGPIHLT 881 +S+ V E N G +++ + R RN+ F ++G +YDGP++ Sbjct: 447 ISQGKIVFEDGNINVNKGMGRFIPRKAFPEHLYQRVKIRNKVFGLQGVSRGMYDGPVYEV 506 Query: 882 RSTFKKYVPTPDRYSS 897 +T K P P SS Sbjct: 507 PATPKYATPAPSAKSS 522 >gi|21493039 A-kinase anchor protein 4 isoform 2 [Homo sapiens] Length = 845 Score = 30.8 bits (68), Expect = 9.4 Identities = 23/90 (25%), Positives = 40/90 (44%), Gaps = 11/90 (12%) Query: 316 DSAAKSLLQGTIQMIQERL-----GSELIQG------LGYRQAWALVGVIDGGSTSCNES 364 DS AK L+ +++IQ L G + + +GY GG ++ S Sbjct: 529 DSLAKDLIVSALKLIQYHLTQQTKGKDTCEEDCPGSTMGYMAQSTQYEKCGGGQSAKALS 588 Query: 365 VRNYENHSSGGKALAQREFYTVDGQKFSVT 394 V+ E+H + G + Q+E +D QK ++ Sbjct: 589 VKQLESHRAPGPSTCQKENQHLDSQKMDMS 618 >gi|21493037 A-kinase anchor protein 4 isoform 1 [Homo sapiens] Length = 854 Score = 30.8 bits (68), Expect = 9.4 Identities = 23/90 (25%), Positives = 40/90 (44%), Gaps = 11/90 (12%) Query: 316 DSAAKSLLQGTIQMIQERL-----GSELIQG------LGYRQAWALVGVIDGGSTSCNES 364 DS AK L+ +++IQ L G + + +GY GG ++ S Sbjct: 538 DSLAKDLIVSALKLIQYHLTQQTKGKDTCEEDCPGSTMGYMAQSTQYEKCGGGQSAKALS 597 Query: 365 VRNYENHSSGGKALAQREFYTVDGQKFSVT 394 V+ E+H + G + Q+E +D QK ++ Sbjct: 598 VKQLESHRAPGPSTCQKENQHLDSQKMDMS 627 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.319 0.136 0.414 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 55,443,663 Number of Sequences: 37866 Number of extensions: 2629473 Number of successful extensions: 7273 Number of sequences better than 10.0: 22 Number of HSP's better than 10.0 without gapping: 6 Number of HSP's successfully gapped in prelim test: 16 Number of HSP's that attempted gapping in prelim test: 7206 Number of HSP's gapped (non-prelim): 44 length of query: 1383 length of database: 18,247,518 effective HSP length: 115 effective length of query: 1268 effective length of database: 13,892,928 effective search space: 17616232704 effective search space used: 17616232704 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.