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Search of human proteins with 13775595
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13775595 tryptase alpha/beta 1 precursor [Homo sapiens]
(275 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13775595 tryptase alpha/beta 1 precursor [Homo sapiens] 590 e-169
gi|68508970 tryptase beta 2 precursor [Homo sapiens] 581 e-166
gi|11321636 tryptase delta 1 [Homo sapiens] 437 e-123
gi|156938340 transmembrane tryptase preproprotein [Homo sapiens] 233 1e-61
gi|13994276 marapsin [Homo sapiens] 227 7e-60
gi|117956391 protease, serine, 33 [Homo sapiens] 217 1e-56
gi|4506153 prostasin preproprotein [Homo sapiens] 204 5e-53
gi|11545839 protease, serine, 22 [Homo sapiens] 202 3e-52
gi|21614531 testisin isoform 2 [Homo sapiens] 196 1e-50
gi|5803197 testisin isoform 1 [Homo sapiens] 191 5e-49
gi|58218970 protease, serine, 36 [Homo sapiens] 185 4e-47
gi|116256363 transmembrane protease, serine 13 [Homo sapiens] 184 7e-47
gi|4503627 coagulation factor XI precursor [Homo sapiens] 182 3e-46
gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo sap... 182 4e-46
gi|170932492 transmembrane protease, serine 5 [Homo sapiens] 179 2e-45
gi|23957702 transmembrane protease, serine 6 [Homo sapiens] 176 2e-44
gi|78191798 plasma kallikrein B1 precursor [Homo sapiens] 176 3e-44
gi|148806900 epidermis-specific serine protease-like protein [Ho... 176 3e-44
gi|110815798 ovochymase 1 [Homo sapiens] 174 1e-43
gi|21614533 testisin isoform 3 [Homo sapiens] 171 5e-43
gi|4758508 transmembrane protease, serine 11D [Homo sapiens] 171 5e-43
gi|239753545 PREDICTED: similar to hCG2041452 [Homo sapiens] 171 8e-43
gi|239748117 PREDICTED: hypothetical protein XP_002346556 [Homo ... 171 8e-43
gi|239742016 PREDICTED: hypothetical protein XP_002342392 [Homo ... 171 8e-43
gi|15559207 elastase 2A preproprotein [Homo sapiens] 169 3e-42
gi|205360905 testis-specific serine protease 1 [Homo sapiens] 167 9e-42
gi|222831592 transmembrane protease, serine 7 [Homo sapiens] 166 2e-41
gi|118498341 chymotrypsin B1 [Homo sapiens] 165 3e-41
gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo sa... 164 8e-41
gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo sa... 164 8e-41
>gi|13775595 tryptase alpha/beta 1 precursor [Homo sapiens]
Length = 275
Score = 590 bits (1522), Expect = e-169
Identities = 275/275 (100%), Positives = 275/275 (100%)
Query: 1 MLNLLLLALPVLASRAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCG 60
MLNLLLLALPVLASRAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCG
Sbjct: 1 MLNLLLLALPVLASRAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCG 60
Query: 61 GSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGA 120
GSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGA
Sbjct: 61 GSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGA 120
Query: 121 DIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKV 180
DIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKV
Sbjct: 121 DIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKV 180
Query: 181 PIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQAG 240
PIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQAG
Sbjct: 181 PIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQAG 240
Query: 241 VVSWGEGCAQPNRPGIYTRVTYYLDWIHHYVPKKP 275
VVSWGEGCAQPNRPGIYTRVTYYLDWIHHYVPKKP
Sbjct: 241 VVSWGEGCAQPNRPGIYTRVTYYLDWIHHYVPKKP 275
>gi|68508970 tryptase beta 2 precursor [Homo sapiens]
Length = 275
Score = 581 bits (1498), Expect = e-166
Identities = 272/275 (98%), Positives = 272/275 (98%)
Query: 1 MLNLLLLALPVLASRAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCG 60
MLNLLLLALPVLASRAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRV YWMHFCG
Sbjct: 1 MLNLLLLALPVLASRAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVRDRYWMHFCG 60
Query: 61 GSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGA 120
GSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGA
Sbjct: 61 GSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGA 120
Query: 121 DIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKV 180
DIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKV
Sbjct: 121 DIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKV 180
Query: 181 PIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQAG 240
PIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQAG
Sbjct: 181 PIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQAG 240
Query: 241 VVSWGEGCAQPNRPGIYTRVTYYLDWIHHYVPKKP 275
VVSWGEGCAQPNRPGIYTRVTYYLDWIHHYVPKKP
Sbjct: 241 VVSWGEGCAQPNRPGIYTRVTYYLDWIHHYVPKKP 275
>gi|11321636 tryptase delta 1 [Homo sapiens]
Length = 242
Score = 437 bits (1123), Expect = e-123
Identities = 200/235 (85%), Positives = 217/235 (92%)
Query: 1 MLNLLLLALPVLASRAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCG 60
ML+LLLLALPVLAS AY APAPGQALQ+ GIVGGQEAPRSKWPWQVSLRV GPYWMHFCG
Sbjct: 8 MLSLLLLALPVLASPAYVAPAPGQALQQTGIVGGQEAPRSKWPWQVSLRVRGPYWMHFCG 67
Query: 61 GSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGA 120
GSLIHPQWVLTAAHCV PD+KDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFY Q GA
Sbjct: 68 GSLIHPQWVLTAAHCVEPDIKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYIIQTGA 127
Query: 121 DIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKV 180
DIALLELEEPVN+SSH+HTVTLPPASETFPPGMPCWVTGWGDVDN+ LPPP+PLK+V+V
Sbjct: 128 DIALLELEEPVNISSHIHTVTLPPASETFPPGMPCWVTGWGDVDNNVHLPPPYPLKEVEV 187
Query: 181 PIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLVCKVNGT 235
P++ENH+C+A+YH G +TG +IVRDDMLCAG+ DSCQGDSGGPLVCKVNGT
Sbjct: 188 PVVENHLCNAEYHTGLHTGHSFQIVRDDMLCAGSENHDSCQGDSGGPLVCKVNGT 242
>gi|156938340 transmembrane tryptase preproprotein [Homo sapiens]
Length = 321
Score = 233 bits (594), Expect = 1e-61
Identities = 126/272 (46%), Positives = 163/272 (59%), Gaps = 15/272 (5%)
Query: 4 LLLLALPVLASRAYAAPAPGQALQRVG--IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGG 61
LLLLA+P ++ R + G IVGG AP WPWQ SLR+ +H CGG
Sbjct: 9 LLLLAVPGVSLRTLQPGCGRPQVSDAGGRIVGGHAAPAGAWPWQASLRLRR---VHVCGG 65
Query: 62 SLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGA- 120
SL+ PQWVLTAAHC + + +V L E + V +II+H + Q G
Sbjct: 66 SLLSPQWVLTAAHCFSGSLNS-SDYQVHLGELEITLSPHFSTVRQIILHSS-PSGQPGTS 123
Query: 121 -DIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVK 179
DIAL+EL PV +SS + V LP AS+ F PG+ CWVTGWG E LPPP+ L++VK
Sbjct: 124 GDIALVELSVPVTLSSRILPVCLPEASDDFCPGIRCWVTGWGYTREGEPLPPPYSLREVK 183
Query: 180 VPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQA 239
V +++ C Y G I++ DMLCA D+CQ DSGGPLVC+VNG W+QA
Sbjct: 184 VSVVDTETCRRDY-----PGPGGSILQPDMLCARGPG-DACQDDSGGPLVCQVNGAWVQA 237
Query: 240 GVVSWGEGCAQPNRPGIYTRVTYYLDWIHHYV 271
G+VSWGEGC +PNRPG+YTRV Y++WI ++
Sbjct: 238 GIVSWGEGCGRPNRPGVYTRVPAYVNWIRRHI 269
>gi|13994276 marapsin [Homo sapiens]
Length = 290
Score = 227 bits (579), Expect = 7e-60
Identities = 120/274 (43%), Positives = 166/274 (60%), Gaps = 9/274 (3%)
Query: 5 LLLALPVLASRAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLI 64
LLL L + RA AA A G+ +VGGQ+ +WPWQVS++ +G HFCGGSLI
Sbjct: 9 LLLLLCFGSQRAKAATACGRPRMLNRMVGGQDTQEGEWPWQVSIQRNGS---HFCGGSLI 65
Query: 65 HPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQD---QLLPVSRIIVHPQFYTAQIGAD 121
QWVLTAAHC + + + +V L + L V ++ +P + AD
Sbjct: 66 AEQWVLTAAHCFR-NTSETSLYQVLLGARQLVQPGPHAMYARVRQVESNPLYQGTASSAD 124
Query: 122 IALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVP 181
+AL+ELE PV ++++ V LP S F GM CWVTGWG ++ LP P L+++ VP
Sbjct: 125 VALVELEAPVPFTNYILPVCLPDPSVIFETGMNCWVTGWGSPSEEDLLPEPRILQKLAVP 184
Query: 182 IMENHICDAKYHLGAYTGDDVRIVRDDMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQA 239
I++ C+ Y G + +++DMLCAG ++D+C+GDSGGPLVC V +WLQA
Sbjct: 185 IIDTPKCNLLYSKDTEFGYQPKTIKNDMLCAGFEEGKKDACKGDSGGPLVCLVGQSWLQA 244
Query: 240 GVVSWGEGCAQPNRPGIYTRVTYYLDWIHHYVPK 273
GV+SWGEGCA+ NRPG+Y RVT + +WIH +PK
Sbjct: 245 GVISWGEGCARQNRPGVYIRVTAHHNWIHRIIPK 278
>gi|117956391 protease, serine, 33 [Homo sapiens]
Length = 280
Score = 217 bits (552), Expect = 1e-56
Identities = 120/269 (44%), Positives = 153/269 (56%), Gaps = 9/269 (3%)
Query: 4 LLLLALPVLASRAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSL 63
LLLL L ++ + A GQ IVGG++ +WPWQ S++ G H CGGSL
Sbjct: 10 LLLLVLGAAGTQGRKSAACGQPRMSSRIVGGRDGRDGEWPWQASIQHRGA---HVCGGSL 66
Query: 64 IHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQL---LPVSRIIVHPQFYTAQIGA 120
I PQWVLTAAHC P A RV+L L +PV R+++ P +
Sbjct: 67 IAPQWVLTAAHCF-PRRALPAEYRVRLGALRLGSTSPRTLSVPVRRVLLPPDYSEDGARG 125
Query: 121 DIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKV 180
D+ALL+L PV +S+ V V LP PPG PC VTGWG + LP PL+ V+V
Sbjct: 126 DLALLQLRRPVPLSARVQPVCLPVPGARPPPGTPCRVTGWGSLRPGVPLPEWRPLQGVRV 185
Query: 181 PIMENHICDAKYHLGAYTGDDVRIVRDDMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQ 238
P++++ CD YH+GA RIV LCAG +D+CQGDSGGPL C +G+W+
Sbjct: 186 PLLDSRTCDGLYHVGADVPQAERIVLPGSLCAGYPQGHKDACQGDSGGPLTCLQSGSWVL 245
Query: 239 AGVVSWGEGCAQPNRPGIYTRVTYYLDWI 267
GVVSWG+GCA PNRPG+YT V Y WI
Sbjct: 246 VGVVSWGKGCALPNRPGVYTSVATYSPWI 274
>gi|4506153 prostasin preproprotein [Homo sapiens]
Length = 343
Score = 204 bits (520), Expect = 5e-53
Identities = 111/273 (40%), Positives = 151/273 (55%), Gaps = 10/273 (3%)
Query: 4 LLLLALPVLASRAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSL 63
LL L L + A A AP + I GG A +WPWQVS+ G +H CGGSL
Sbjct: 18 LLYLGLLRSGTGAEGAEAPCGVAPQARITGGSSAVAGQWPWQVSITYEG---VHVCGGSL 74
Query: 64 IHPQWVLTAAHCVGPDVKDLAALRVQLREQHL--YYQD-QLLPVSRIIVHPQFYTAQIGA 120
+ QWVL+AAHC P A V+L L Y +D ++ + II HP +
Sbjct: 75 VSEQWVLSAAHCF-PSEHHKEAYEVKLGAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQG 133
Query: 121 DIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKV 180
DIALL+L P+ S ++ + LP A+ +FP G+ C VTGWG V L P PL+Q++V
Sbjct: 134 DIALLQLSRPITFSRYIRPICLPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEV 193
Query: 181 PIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTR--RDSCQGDSGGPLVCKVNGTWLQ 238
P++ C+ Y++ A ++ V++DM+CAG +D+CQGDSGGPL C V G W
Sbjct: 194 PLISRETCNCLYNIDA-KPEEPHFVQEDMVCAGYVEGGKDACQGDSGGPLSCPVEGLWYL 252
Query: 239 AGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHYV 271
G+VSWG+ C NRPG+YT + Y WI V
Sbjct: 253 TGIVSWGDACGARNRPGVYTLASSYASWIQSKV 285
>gi|11545839 protease, serine, 22 [Homo sapiens]
Length = 317
Score = 202 bits (513), Expect = 3e-52
Identities = 110/277 (39%), Positives = 161/277 (58%), Gaps = 15/277 (5%)
Query: 3 NLLLLALPVL--ASRAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCG 60
+LLLLA + A+R PA G+ Q +VGG+++ S+WPW VS++ +G H C
Sbjct: 20 SLLLLASTAILNAARIPVPPACGKPQQLNRVVGGEDSTDSEWPWIVSIQKNGT---HHCA 76
Query: 61 GSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYY---QDQLLPVSRIIVHPQF-YTA 116
GSL+ +WV+TAAHC ++ V L L + Q + V+ + HP + +
Sbjct: 77 GSLLTSRWVITAAHCFKDNLNKPYLFSVLLGAWQLGNPGSRSQKVGVAWVEPHPVYSWKE 136
Query: 117 QIGADIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLK 176
ADIAL+ LE + S V + LP AS PP CW++GWG + + LP P L+
Sbjct: 137 GACADIALVRLERSIQFSERVLPICLPDASIHLPPNTHCWISGWGSIQDGVPLPHPQTLQ 196
Query: 177 QVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAG--NTRRDSCQGDSGGPLVCKVNG 234
++KVPI+++ +C Y GA G + +DMLCAG RD+C GDSGGPL+C+V+G
Sbjct: 197 KLKVPIIDSEVCSHLYWRGAGQGP----ITEDMLCAGYLEGERDACLGDSGGPLMCQVDG 252
Query: 235 TWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHYV 271
WL AG++SWGEGCA+ NRPG+Y ++ + W+ V
Sbjct: 253 AWLLAGIISWGEGCAERNRPGVYISLSAHRSWVEKIV 289
>gi|21614531 testisin isoform 2 [Homo sapiens]
Length = 312
Score = 196 bits (499), Expect = 1e-50
Identities = 108/265 (40%), Positives = 149/265 (56%), Gaps = 26/265 (9%)
Query: 18 AAPAPGQALQRV---GIVGGQEAPRSKWPWQVSLRVHGPYW-MHFCGGSLIHPQWVLTAA 73
AAP G +RV IVGG++A +WPWQ SLR+ W H CG SL+ +W LTAA
Sbjct: 26 AAPLSGPCGRRVITSRIVGGEDAELGRWPWQGSLRL----WDSHVCGVSLLSHRWALTAA 81
Query: 74 HCVGPDVKDLAALRVQLREQ---------HLYYQDQLLPVSRIIVHPQFYTAQIGADIAL 124
HC D+ D + VQ + YY VS I + P+ Y DIAL
Sbjct: 82 HCFETDLSDPSGWMVQFGQLTSMPSFWSLQAYYTRYF--VSNIYLSPR-YLGNSPYDIAL 138
Query: 125 LELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIME 184
++L PV + H+ + L ++ F CWVTGWG + DE LP P L++V+V I+
Sbjct: 139 VKLSAPVTYTKHIQPICLQASTFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIIN 198
Query: 185 NHICDAKYHLGAYTGDDVRIVRDDMLCAGNTR--RDSCQGDSGGPLVCKVNGTWLQAGVV 242
N +C+ + ++ D + DM+CAGN + +D+C GDSGGPL C NG W Q GVV
Sbjct: 199 NSMCNHLFLKYSFRKD----IFGDMVCAGNAQGGKDACFGDSGGPLACNKNGLWYQIGVV 254
Query: 243 SWGEGCAQPNRPGIYTRVTYYLDWI 267
SWG GC +PNRPG+YT ++++ +WI
Sbjct: 255 SWGVGCGRPNRPGVYTNISHHFEWI 279
>gi|5803197 testisin isoform 1 [Homo sapiens]
Length = 314
Score = 191 bits (486), Expect = 5e-49
Identities = 108/267 (40%), Positives = 149/267 (55%), Gaps = 28/267 (10%)
Query: 18 AAPAPGQALQRV---GIVGGQEAPRSKWPWQVSLRVHGPYW-MHFCGGSLIHPQWVLTAA 73
AAP G +RV IVGG++A +WPWQ SLR+ W H CG SL+ +W LTAA
Sbjct: 26 AAPLSGPCGRRVITSRIVGGEDAELGRWPWQGSLRL----WDSHVCGVSLLSHRWALTAA 81
Query: 74 HCVGP--DVKDLAALRVQLREQ---------HLYYQDQLLPVSRIIVHPQFYTAQIGADI 122
HC D+ D + VQ + YY VS I + P+ Y DI
Sbjct: 82 HCFETYSDLSDPSGWMVQFGQLTSMPSFWSLQAYYTRYF--VSNIYLSPR-YLGNSPYDI 138
Query: 123 ALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPI 182
AL++L PV + H+ + L ++ F CWVTGWG + DE LP P L++V+V I
Sbjct: 139 ALVKLSAPVTYTKHIQPICLQASTFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAI 198
Query: 183 MENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTR--RDSCQGDSGGPLVCKVNGTWLQAG 240
+ N +C+ + ++ D + DM+CAGN + +D+C GDSGGPL C NG W Q G
Sbjct: 199 INNSMCNHLFLKYSFRKD----IFGDMVCAGNAQGGKDACFGDSGGPLACNKNGLWYQIG 254
Query: 241 VVSWGEGCAQPNRPGIYTRVTYYLDWI 267
VVSWG GC +PNRPG+YT ++++ +WI
Sbjct: 255 VVSWGVGCGRPNRPGVYTNISHHFEWI 281
>gi|58218970 protease, serine, 36 [Homo sapiens]
Length = 855
Score = 185 bits (469), Expect = 4e-47
Identities = 107/251 (42%), Positives = 138/251 (54%), Gaps = 17/251 (6%)
Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHC--VGPDVKDLAALRV 88
IVGG A WPWQVSL G H CGGSLI P WVL+AAHC ++ A V
Sbjct: 47 IVGGSNAQPGTWPWQVSLHHGGG---HICGGSLIAPSWVLSAAHCFMTNGTLEPAAEWSV 103
Query: 89 QLREQHLYYQDQLLP------VSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTL 142
L ++ QD L V+ I+V + ++GAD+ALL L P ++ V V L
Sbjct: 104 LLG---VHSQDGPLDGAHTRAVAAIVVPANYSQVELGADLALLRLASPASLGPAVWPVCL 160
Query: 143 PPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDV 202
P AS F G CW TGWGDV + LP P+ L++V++ ++ C Y +
Sbjct: 161 PRASHRFVHGTACWATGWGDVQEADPLPLPWVLQEVELRLLGEATCQCLYSQPGPFNLTL 220
Query: 203 RIVRDDMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRV 260
+I+ MLCAG RRD+CQGDSGGPLVC+ G W QAG+ S+G GC + NRPG++T V
Sbjct: 221 QIL-PGMLCAGYPEGRRDTCQGDSGGPLVCEEGGRWFQAGITSFGFGCGRRNRPGVFTAV 279
Query: 261 TYYLDWIHHYV 271
Y WI V
Sbjct: 280 ATYEAWIREQV 290
Score = 77.8 bits (190), Expect = 1e-14
Identities = 67/241 (27%), Positives = 102/241 (42%), Gaps = 22/241 (9%)
Query: 36 EAPR-SKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHC-VGPDVKDLAALRVQLREQ 93
+APR WPW+ + V G C G+L+ WVL A C + P+ D +
Sbjct: 327 KAPRPGAWPWEAQVMVPGS---RPCHGALVSESWVLAPASCFLDPNSSDSPPRDLDAWRV 383
Query: 94 HLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASETFPPGM 153
L + + V+R++ H + +D+ALL+L PVN+S+ V LP F PG
Sbjct: 384 LLPSRPRAERVARLVQHENA-SWDNASDLALLQLRTPVNLSAASRPVCLPHPEHYFLPGS 442
Query: 154 PCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRD--DMLC 211
C + WG + P P ++ ++ C Y G V + D LC
Sbjct: 443 RCRLARWGRGE-----PALGPGALLEAELLGGWWCHCLY---GRQGAAVPLPGDPPHALC 494
Query: 212 AGNTRRD---SCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWIH 268
++ SC DS L+C+ GTW AG+ + GC RP + + + WI
Sbjct: 495 PAYQEKEEVGSCWNDSRWSLLCQEEGTWFLAGIRDFPSGCL---RPRAFFPLQTHGPWIS 551
Query: 269 H 269
H
Sbjct: 552 H 552
Score = 73.6 bits (179), Expect = 2e-13
Identities = 63/211 (29%), Positives = 87/211 (41%), Gaps = 30/211 (14%)
Query: 42 WPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCV-GPDVKDLAALRVQLREQHLYYQDQ 100
WPW + V G C G L+ P WVL A HCV P + + V L Q
Sbjct: 601 WPWLAEVHVAGD---RVCTGILLAPGWVLAATHCVLRPGSTTVPYIEVYLGRAGASSLPQ 657
Query: 101 LLPVSRIIVH---PQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWV 157
VSR+++ PQ + +ALLEL V S + L PA PPG CWV
Sbjct: 658 GHQVSRLVISIRLPQH--LGLRPPLALLELSSRVEPSPSALPICLHPAG--IPPGASCWV 713
Query: 158 TGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCA--GNT 215
GW + +R+P V I+ ICD Y I+ LC
Sbjct: 714 LGW--KEPQDRVP-----VAAAVSILTQRICDCLYQ---------GILPPGTLCVLYAEG 757
Query: 216 RRDSCQGDSGGPLVCKV-NGTWLQAGVVSWG 245
+ + C+ S PL+C++ G+W+ G+ G
Sbjct: 758 QENRCEMTSAPPLLCQMTEGSWILVGMAVQG 788
>gi|116256363 transmembrane protease, serine 13 [Homo sapiens]
Length = 567
Score = 184 bits (467), Expect = 7e-47
Identities = 100/241 (41%), Positives = 137/241 (56%), Gaps = 14/241 (5%)
Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPD-VKDLAALRVQ 89
IVGG A SKWPWQVSL H CGG+LI QWVLTAAHC K L +V
Sbjct: 326 IVGGALASDSKWPWQVSLHFGTT---HICGGTLIDAQWVLTAAHCFFVTREKVLEGWKVY 382
Query: 90 LREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASETF 149
+L+ + ++ II++ + + DIAL+ L +P+ +S+H+H LP +TF
Sbjct: 383 AGTSNLHQLPEAASIAEIIINSNYTDEEDDYDIALMRLSKPLTLSAHIHPACLPMHGQTF 442
Query: 150 PPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDM 209
CW+TG+G + PF L++V+V +++ C+ +Y + M
Sbjct: 443 SLNETCWITGFGKTRETDDKTSPF-LREVQVNLIDFKKCNDYLVYDSY-------LTPRM 494
Query: 210 LCAGNTR--RDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWI 267
+CAG+ R RDSCQGDSGGPLVC+ N W AGV SWG GC Q N+PG+YT+VT L WI
Sbjct: 495 MCAGDLRGGRDSCQGDSGGPLVCEQNNRWYLAGVTSWGTGCGQRNKPGVYTKVTEVLPWI 554
Query: 268 H 268
+
Sbjct: 555 Y 555
>gi|4503627 coagulation factor XI precursor [Homo sapiens]
Length = 625
Score = 182 bits (462), Expect = 3e-46
Identities = 99/242 (40%), Positives = 130/242 (53%), Gaps = 16/242 (6%)
Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQ- 89
IVGG + R +WPWQV+L P H CGGS+I QW+LTAAHC V+ LRV
Sbjct: 388 IVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFY-GVESPKILRVYS 446
Query: 90 --LREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASE 147
L + + V II+H Q+ A+ G DIALL+LE VN + + LP +
Sbjct: 447 GILNQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVNYTDSQRPICLPSKGD 506
Query: 148 TFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRD 207
CWVTGWG +++ L++ K+P++ N C +Y T
Sbjct: 507 RNVIYTDCWVTGWGYRKLRDKIQNT--LQKAKIPLVTNEECQKRYRGHKIT--------H 556
Query: 208 DMLCAGNTR--RDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLD 265
M+CAG +D+C+GDSGGPL CK N W G+ SWGEGCAQ RPG+YT V Y+D
Sbjct: 557 KMICAGYREGGKDACKGDSGGPLSCKHNEVWHLVGITSWGEGCAQRERPGVYTNVVEYVD 616
Query: 266 WI 267
WI
Sbjct: 617 WI 618
>gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo
sapiens]
Length = 454
Score = 182 bits (461), Expect = 4e-46
Identities = 102/248 (41%), Positives = 139/248 (56%), Gaps = 19/248 (7%)
Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90
IVGG + S+WPWQ SL+ G H CGGS+I P W++TAAHCV D+ + +Q+
Sbjct: 217 IVGGNMSLLSQWPWQASLQFQG---YHLCGGSVITPLWIITAAHCVY-DLYLPKSWTIQV 272
Query: 91 REQHLYYQDQLLP---VSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASE 147
L D P V +I+ H ++ ++G DIAL++L P+ + + V LP + E
Sbjct: 273 GLVSLL--DNPAPSHLVEKIVYHSKYKPKRLGNDIALMKLAGPLTFNEMIQPVCLPNSEE 330
Query: 148 TFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRD 207
FP G CW +GWG ++ P L VP++ N IC+ H Y G I+
Sbjct: 331 NFPDGKVCWTSGWGATEDGAGDASPV-LNHAAVPLISNKICN---HRDVYGG----IISP 382
Query: 208 DMLCAGNTRR--DSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLD 265
MLCAG DSCQGDSGGPLVC+ W G S+G GCA+ N+PG+YTRVT +LD
Sbjct: 383 SMLCAGYLTGGVDSCQGDSGGPLVCQERRLWKLVGATSFGIGCAEVNKPGVYTRVTSFLD 442
Query: 266 WIHHYVPK 273
WIH + +
Sbjct: 443 WIHEQMER 450
>gi|170932492 transmembrane protease, serine 5 [Homo sapiens]
Length = 457
Score = 179 bits (455), Expect = 2e-45
Identities = 100/243 (41%), Positives = 131/243 (53%), Gaps = 16/243 (6%)
Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGP-DVKDLAALRVQ 89
IVGGQ +WPWQ S+ + + H CGGS++ P+WV+TAAHC+ + L++ RV
Sbjct: 218 IVGGQSVAPGRWPWQASVALG---FRHTCGGSVLAPRWVVTAAHCMHSFRLARLSSWRVH 274
Query: 90 --LREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASE 147
L Q V RII HP + D+ALL L+ +N S V V LP +
Sbjct: 275 AGLVSHSAVRPHQGALVERIIPHPLYSAQNHDYDVALLRLQTALNFSDTVGAVCLPAKEQ 334
Query: 148 TFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRD 207
FP G CWV+GWG L+ VP+ +C++ Y+G +
Sbjct: 335 HFPKGSRCWVSGWGHTHPSHTYSSDM-LQDTVVPLFSTQLCNSSC---VYSG----ALTP 386
Query: 208 DMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLD 265
MLCAG + R D+CQGDSGGPLVC TW GVVSWG GCA+PN PG+Y +V +LD
Sbjct: 387 RMLCAGYLDGRADACQGDSGGPLVCPDGDTWRLVGVVSWGRGCAEPNHPGVYAKVAEFLD 446
Query: 266 WIH 268
WIH
Sbjct: 447 WIH 449
>gi|23957702 transmembrane protease, serine 6 [Homo sapiens]
Length = 811
Score = 176 bits (447), Expect = 2e-44
Identities = 100/248 (40%), Positives = 136/248 (54%), Gaps = 21/248 (8%)
Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRV-- 88
IVGG + +WPWQ SL+V G H CGG+LI +WV+TAAHC D L
Sbjct: 577 IVGGAVSSEGEWPWQASLQVRG---RHICGGALIADRWVITAAHCFQEDSMASTVLWTVF 633
Query: 89 --QLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPAS 146
++ + + + VSR+++HP D+ALL+L+ PV S+ V V LP S
Sbjct: 634 LGKVWQNSRWPGEVSFKVSRLLLHPYHEEDSHDYDVALLQLDHPVVRSAAVRPVCLPARS 693
Query: 147 ETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVR 206
F PG+ CW+TGWG + E P L++V V ++ +C Y V
Sbjct: 694 HFFEPGLHCWITGWGAL--REGGPISNALQKVDVQLIPQDLCSEVYRYQ---------VT 742
Query: 207 DDMLCAG--NTRRDSCQGDSGGPLVCK-VNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYY 263
MLCAG ++D+CQGDSGGPLVCK ++G W AG+VSWG GC +PN G+YTR+T
Sbjct: 743 PRMLCAGYRKGKKDACQGDSGGPLVCKALSGRWFLAGLVSWGLGCGRPNYFGVYTRITGV 802
Query: 264 LDWIHHYV 271
+ WI V
Sbjct: 803 ISWIQQVV 810
>gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]
Length = 638
Score = 176 bits (445), Expect = 3e-44
Identities = 96/241 (39%), Positives = 137/241 (56%), Gaps = 14/241 (5%)
Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCV-GPDVKDLAALRVQ 89
IVGG + +WPWQVSL+V H CGGSLI QWVLTAAHC G ++D+ +
Sbjct: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450
Query: 90 LREQHLYYQDQ-LLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASET 148
+ +D + II+H + ++ DIAL++L+ P+N + + LP +T
Sbjct: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDT 510
Query: 149 FPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDD 208
CWVTGWG + E+ L++V +P++ N C +Y D +I +
Sbjct: 511 STIYTNCWVTGWGF--SKEKGEIQNILQKVNIPLVTNEECQKRYQ-------DYKITQR- 560
Query: 209 MLCAGNTR--RDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDW 266
M+CAG +D+C+GDSGGPLVCK NG W G+ SWGEGCA+ +PG+YT+V Y+DW
Sbjct: 561 MVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDW 620
Query: 267 I 267
I
Sbjct: 621 I 621
>gi|148806900 epidermis-specific serine protease-like protein [Homo
sapiens]
Length = 328
Score = 176 bits (445), Expect = 3e-44
Identities = 96/256 (37%), Positives = 146/256 (57%), Gaps = 22/256 (8%)
Query: 23 GQALQRVGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKD 82
GQ + +VGGQ+A +WPWQVSL + CGGSL+ + +LTAAHC+ P
Sbjct: 20 GQPVYSSRVVGGQDAAAGRWPWQVSLHFDHNF---ICGGSLVSERLILTAAHCIQPTWTT 76
Query: 83 ------LAALRV-QLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSS 135
L ++ V R++ YY VS+I++HP++ AD+ALL+L V +S
Sbjct: 77 FSYTVWLGSITVGDSRKRVKYY------VSKIVIHPKYQDTT--ADVALLKLSSQVTFTS 128
Query: 136 HVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYH-L 194
+ + LP ++ CWVTGWG V L++ +VPI++ C+ Y+ +
Sbjct: 129 AILPICLPSVTKQLAIPPFCWVTGWGKVKESSDRDYHSALQEAEVPIIDRQACEQLYNPI 188
Query: 195 GAYTGDDVRIVRDDMLCAGNTR--RDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPN 252
G + ++++D +CAG+T+ +DSC+GDSGGPL C ++G W+Q GVVSWG C + +
Sbjct: 189 GIFLPALEPVIKEDKICAGDTQNMKDSCKGDSGGPLSCHIDGVWIQTGVVSWGLECGK-S 247
Query: 253 RPGIYTRVTYYLDWIH 268
PG+YT V YY WI+
Sbjct: 248 LPGVYTNVIYYQKWIN 263
>gi|110815798 ovochymase 1 [Homo sapiens]
Length = 1134
Score = 174 bits (440), Expect = 1e-43
Identities = 100/247 (40%), Positives = 140/247 (56%), Gaps = 24/247 (9%)
Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRV-- 88
I GG+EA WPWQV LR G Y CGG++I+P W+LTAAHCV L+ +
Sbjct: 575 IAGGEEACPHCWPWQVGLRFLGDYQ---CGGAIINPVWILTAAHCVQLKNNPLSWTIIAG 631
Query: 89 ----QLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPP 144
L+E +Q+ IIVH F T +DIAL++L P+ +S V V LP
Sbjct: 632 DHDRNLKES----TEQVRRAKHIIVHEDFNTLSYDSDIALIQLSSPLEYNSVVRPVCLPH 687
Query: 145 ASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRI 204
++E C VTGWG + D L L+Q++V ++E +C+ Y+ A+ G
Sbjct: 688 SAEPLFSSEICAVTGWGSISADGGLAS--RLQQIQVHVLEREVCEHTYY-SAHPGG---- 740
Query: 205 VRDDMLCAG---NTRRDSCQGDSGGPLVCK-VNGTWLQAGVVSWGEGCAQPNRPGIYTRV 260
+ + M+CAG + +D CQGDSGGPLVC+ NG ++ G+VSWG GC QP +PG++ RV
Sbjct: 741 ITEKMICAGFAASGEKDFCQGDSGGPLVCRHENGPFVLYGIVSWGAGCVQPWKPGVFARV 800
Query: 261 TYYLDWI 267
+LDWI
Sbjct: 801 MIFLDWI 807
Score = 134 bits (338), Expect = 7e-32
Identities = 87/243 (35%), Positives = 131/243 (53%), Gaps = 28/243 (11%)
Query: 43 PWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGP-DVKDLAALRVQLREQHLYYQD-- 99
PWQVSL+ HFCGGSLI V+TAAHC+ K L + V E L+ +D
Sbjct: 59 PWQVSLKSDEH---HFCGGSLIQEDRVVTAAHCLDSLSEKQLKNITVTSGEYSLFQKDKQ 115
Query: 100 -QLLPVSRIIVHPQFYTAQ-IGADIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWV 157
Q +PVS+II HP++ + + + DIALL L+ V + V + LP + + PG+ C
Sbjct: 116 EQNIPVSKIITHPEYNSREYMSPDIALLYLKHKVKFGNAVQPICLPDSDDKVEPGILCLS 175
Query: 158 TGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAG--NT 215
+GWG + L+++++PIM++ C+ ++ + MLCAG +
Sbjct: 176 SGWGKISKTSEYSN--VLQEMELPIMDDRACNT-----VLKSMNLPPLGRTMLCAGFPDW 228
Query: 216 RRDSCQGDSGGPLVC-KVNGTWLQAGVVSWGEGCAQPNRP----------GIYTRVTYYL 264
D+CQGDSGGPLVC + G W+ AG+ SW GCA + P GI+++V+ +
Sbjct: 229 GMDACQGDSGGPLVCRRGGGIWILAGITSWVAGCAGGSVPVRNNHVKASLGIFSKVSELM 288
Query: 265 DWI 267
D+I
Sbjct: 289 DFI 291
>gi|21614533 testisin isoform 3 [Homo sapiens]
Length = 300
Score = 171 bits (434), Expect = 5e-43
Identities = 102/265 (38%), Positives = 139/265 (52%), Gaps = 38/265 (14%)
Query: 18 AAPAPGQALQRV---GIVGGQEAPRSKWPWQVSLRVHGPYW-MHFCGGSLIHPQWVLTAA 73
AAP G +RV IVGG++A +WPWQ SLR+ W H CG SL+ +W LTAA
Sbjct: 26 AAPLSGPCGRRVITSRIVGGEDAELGRWPWQGSLRL----WDSHVCGVSLLSHRWALTAA 81
Query: 74 HCVGP--DVKDLAALRVQLREQ---------HLYYQDQLLPVSRIIVHPQFYTAQIGADI 122
HC D+ D + VQ + YY VS I + P+ Y DI
Sbjct: 82 HCFETYSDLSDPSGWMVQFGQLTSMPSFWSLQAYYTRYF--VSNIYLSPR-YLGNSPYDI 138
Query: 123 ALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPI 182
AL++L PV + H+ + L ++ F CWVTGWG + DE LP P L++V+V I
Sbjct: 139 ALVKLSAPVTYTKHIQPICLQASTFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAI 198
Query: 183 MENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQAGVV 242
+ N +C+ + ++ D + DM GDSGGPL C NG W Q GVV
Sbjct: 199 INNSMCNHLFLKYSFRKD----IFGDM------------GDSGGPLACNKNGLWYQIGVV 242
Query: 243 SWGEGCAQPNRPGIYTRVTYYLDWI 267
SWG GC +PNRPG+YT ++++ +WI
Sbjct: 243 SWGVGCGRPNRPGVYTNISHHFEWI 267
>gi|4758508 transmembrane protease, serine 11D [Homo sapiens]
Length = 418
Score = 171 bits (434), Expect = 5e-43
Identities = 99/243 (40%), Positives = 136/243 (55%), Gaps = 23/243 (9%)
Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKD---LAALR 87
I+GG EA WPWQVSLR++ H CGGSLI+ W+LTAAHC + +A
Sbjct: 187 ILGGTEAEEGSWPWQVSLRLNNA---HHCGGSLINNMWILTAAHCFRSNSNPRDWIATSG 243
Query: 88 VQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASE 147
+ L + V I++H + +A DIAL+ LE V + +H+V LP A++
Sbjct: 244 ISTTFPKLRMR-----VRNILIHNNYKSATHENDIALVRLENSVTFTKDIHSVCLPAATQ 298
Query: 148 TFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRD 207
PPG +VTGWG + P L+Q +V I+ N +C+A + +Y G +
Sbjct: 299 NIPPGSTAYVTGWGAQEYAGHTVP--ELRQGQVRIISNDVCNAPH---SYNG----AILS 349
Query: 208 DMLCAGNTRR--DSCQGDSGGPLVCK-VNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYL 264
MLCAG + D+CQGDSGGPLV + W G+VSWG+ C P++PG+YTRVT YL
Sbjct: 350 GMLCAGVPQGGVDACQGDSGGPLVQEDSRRLWFIVGIVSWGDQCGLPDKPGVYTRVTAYL 409
Query: 265 DWI 267
DWI
Sbjct: 410 DWI 412
>gi|239753545 PREDICTED: similar to hCG2041452 [Homo sapiens]
Length = 410
Score = 171 bits (432), Expect = 8e-43
Identities = 97/243 (39%), Positives = 131/243 (53%), Gaps = 18/243 (7%)
Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDV-----KDLAA 85
++GG AP KWPWQVSL+ +H CGGSLI +WVLTAAHCV + L A
Sbjct: 163 MIGGLPAPNKKWPWQVSLQTSN---IHHCGGSLIDRRWVLTAAHCVFRGCGWEGGRWLLA 219
Query: 86 LRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPA 145
+ + + +D + P + F A + +DIAL L VN SSH+ LP
Sbjct: 220 GIGRWDQAWKHLEDIIFPSN-------FDFATLTSDIALALLAYSVNYSSHIQPACLPEK 272
Query: 146 SETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIV 205
G CWVTGWG V P P L++ ++ IM + C L ++V
Sbjct: 273 LFEVEAGTECWVTGWGQVSESVSGPMPLVLQETELNIMRHEKCCEM--LKNKNISKSKMV 330
Query: 206 RDDMLCAGNTR-RDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYL 264
+C N + +D+CQGDSGGPLVC++NGTW+Q G+VSWG GC + PG+YT V++Y
Sbjct: 331 TRGTVCGYNDQGKDACQGDSGGPLVCELNGTWVQVGIVSWGIGCGRKGYPGVYTEVSFYK 390
Query: 265 DWI 267
WI
Sbjct: 391 KWI 393
>gi|239748117 PREDICTED: hypothetical protein XP_002346556 [Homo
sapiens]
Length = 410
Score = 171 bits (432), Expect = 8e-43
Identities = 97/243 (39%), Positives = 131/243 (53%), Gaps = 18/243 (7%)
Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDV-----KDLAA 85
++GG AP KWPWQVSL+ +H CGGSLI +WVLTAAHCV + L A
Sbjct: 163 MIGGLPAPNKKWPWQVSLQTSN---IHHCGGSLIDRRWVLTAAHCVFRGCGWEGGRWLLA 219
Query: 86 LRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPA 145
+ + + +D + P + F A + +DIAL L VN SSH+ LP
Sbjct: 220 GIGRWDQAWKHLEDIIFPSN-------FDFATLTSDIALALLAYSVNYSSHIQPACLPEK 272
Query: 146 SETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIV 205
G CWVTGWG V P P L++ ++ IM + C L ++V
Sbjct: 273 LFEVEAGTECWVTGWGQVSESVSGPMPLVLQETELNIMRHEKCCEM--LKNKNISKSKMV 330
Query: 206 RDDMLCAGNTR-RDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYL 264
+C N + +D+CQGDSGGPLVC++NGTW+Q G+VSWG GC + PG+YT V++Y
Sbjct: 331 TRGTVCGYNDQGKDACQGDSGGPLVCELNGTWVQVGIVSWGIGCGRKGYPGVYTEVSFYK 390
Query: 265 DWI 267
WI
Sbjct: 391 KWI 393
>gi|239742016 PREDICTED: hypothetical protein XP_002342392 [Homo
sapiens]
Length = 410
Score = 171 bits (432), Expect = 8e-43
Identities = 97/243 (39%), Positives = 131/243 (53%), Gaps = 18/243 (7%)
Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDV-----KDLAA 85
++GG AP KWPWQVSL+ +H CGGSLI +WVLTAAHCV + L A
Sbjct: 163 MIGGLPAPNKKWPWQVSLQTSN---IHHCGGSLIDRRWVLTAAHCVFRGCGWEGGRWLLA 219
Query: 86 LRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPA 145
+ + + +D + P + F A + +DIAL L VN SSH+ LP
Sbjct: 220 GIGRWDQAWKHLEDIIFPSN-------FDFATLTSDIALALLAYSVNYSSHIQPACLPEK 272
Query: 146 SETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIV 205
G CWVTGWG V P P L++ ++ IM + C L ++V
Sbjct: 273 LFEVEAGTECWVTGWGQVSESVSGPMPLVLQETELNIMRHEKCCEM--LKNKNISKSKMV 330
Query: 206 RDDMLCAGNTR-RDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYL 264
+C N + +D+CQGDSGGPLVC++NGTW+Q G+VSWG GC + PG+YT V++Y
Sbjct: 331 TRGTVCGYNDQGKDACQGDSGGPLVCELNGTWVQVGIVSWGIGCGRKGYPGVYTEVSFYK 390
Query: 265 DWI 267
WI
Sbjct: 391 KWI 393
>gi|15559207 elastase 2A preproprotein [Homo sapiens]
Length = 269
Score = 169 bits (427), Expect = 3e-42
Identities = 105/281 (37%), Positives = 152/281 (54%), Gaps = 25/281 (8%)
Query: 1 MLNLLLLALPVLASRAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVHGP-YWMHFC 59
M+ LLL+ V + + P + RV VGG+EA + WPWQVSL+ W H C
Sbjct: 1 MIRTLLLSTLVAGALSCGDPTYPPYVTRV--VGGEEARPNSWPWQVSLQYSSNGKWYHTC 58
Query: 60 GGSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQ---LLPVSRIIVHPQFYTA 116
GGSLI WVLTAAHC+ RV L +LY + + VS+I+VH + +
Sbjct: 59 GGSLIANSWVLTAAHCISSS----RTYRVGLGRHNLYVAESGSLAVSVSKIVVHKDWNSN 114
Query: 117 QI--GADIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFP 174
QI G DIALL+L PV+++ + LPPA P PC+VTGWG + + +P
Sbjct: 115 QISKGNDIALLKLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGAVPD--V 172
Query: 175 LKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTR-RDSCQGDSGGPLVCKV- 232
L+Q ++ +++ C + G+ V+ M+CAG SC GDSGGPL C+
Sbjct: 173 LQQGRLLVVDYATCSSSAWWGS-------SVKTSMICAGGDGVISSCNGDSGGPLNCQAS 225
Query: 233 NGTWLQAGVVSWGE--GCAQPNRPGIYTRVTYYLDWIHHYV 271
+G W G+VS+G GC ++P ++TRV+ Y+DWI+ +
Sbjct: 226 DGRWQVHGIVSFGSRLGCNYYHKPSVFTRVSNYIDWINSVI 266
>gi|205360905 testis-specific serine protease 1 [Homo sapiens]
Length = 318
Score = 167 bits (423), Expect = 9e-42
Identities = 92/246 (37%), Positives = 131/246 (53%), Gaps = 17/246 (6%)
Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPD------VKDLA 84
+ GG E+ R +WPWQ SLR+ H CGGSL+ +WVL+AAHC L
Sbjct: 55 VAGGVESARGRWPWQASLRLRR---RHRCGGSLLSRRWVLSAAHCFQKHYYPSEWTVQLG 111
Query: 85 ALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPP 144
L + +L V IIV+P + DIALL L V ++++ + +
Sbjct: 112 ELTSRPTPWNLRAYSSRYKVQDIIVNPDALGV-LRNDIALLRLASSVTYNAYIQPICIES 170
Query: 145 ASETFPPGMPCWVTGWGDVD-NDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVR 203
++ F CWVTGWG + + LPPP+ L++ +V I+ N C+ + +
Sbjct: 171 STFNFVHRPDCWVTGWGLISPSGTPLPPPYNLREAQVTILNNTRCNYLFEQPSSRS---- 226
Query: 204 IVRDDMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVT 261
++ D M CAG + D+C+GDSGGPLVC +G W Q G+VSWG C QPNRPG+YT ++
Sbjct: 227 MIWDSMFCAGAEDGSVDTCKGDSGGPLVCDKDGLWYQVGIVSWGMDCGQPNRPGVYTNIS 286
Query: 262 YYLDWI 267
Y WI
Sbjct: 287 VYFHWI 292
>gi|222831592 transmembrane protease, serine 7 [Homo sapiens]
Length = 717
Score = 166 bits (420), Expect = 2e-41
Identities = 97/255 (38%), Positives = 137/255 (53%), Gaps = 33/255 (12%)
Query: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCV-GPDVKDLAALRVQ 89
I+GG + WPWQVSL G +CG S+I +W+L+AAHC G + D
Sbjct: 480 IIGGTDTLEGGWPWQVSLHFVGSA---YCGASVISREWLLSAAHCFHGNRLSDPTPWTAH 536
Query: 90 LREQHLYYQDQ---LLPVSRIIVHPQFYTAQIGADIALLELEE--PVNVSSHVHTVTLPP 144
L +Y Q + PV RI+VH + + DIALL+L P + + + +PP
Sbjct: 537 LG---MYVQGNAKFVSPVRRIVVHEYYNSQTFDYDIALLQLSIAWPETLKQLIQPICIPP 593
Query: 145 ASETFPPGMPCWVTGWG---DVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDD 201
+ G CWVTGWG + DN L L+Q +V +++ +C + Y
Sbjct: 594 TGQRVRSGEKCWVTGWGRRHEADNKGSLV----LQQAEVELIDQTLCVSTYG-------- 641
Query: 202 VRIVRDDMLCAG--NTRRDSCQGDSGGPLVC--KVNGTWLQAGVVSWGEGCAQPNRPGIY 257
I+ MLCAG + +RD+C+GDSGGPL C K +G W+ G+VSWG G +PN PG+Y
Sbjct: 642 --IITSRMLCAGIMSGKRDACKGDSGGPLSCRRKSDGKWILTGIVSWGHGSGRPNFPGVY 699
Query: 258 TRVTYYLDWIHHYVP 272
TRV+ ++ WIH YVP
Sbjct: 700 TRVSNFVPWIHKYVP 714
>gi|118498341 chymotrypsin B1 [Homo sapiens]
Length = 263
Score = 165 bits (418), Expect = 3e-41
Identities = 98/272 (36%), Positives = 135/272 (49%), Gaps = 21/272 (7%)
Query: 1 MLNLLLLALPVLASRAYAAPAPG-----QALQRVGIVGGQEAPRSKWPWQVSLRVHGPYW 55
M +L LL+ L A+ P L R IV G++A WPWQVSL+ +
Sbjct: 1 MASLWLLSCFSLVGAAFGCGVPAIHPVLSGLSR--IVNGEDAVPGSWPWQVSLQDKTGF- 57
Query: 56 MHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYT 115
HFCGGSLI WV+TAAHC G D+ + + Q+L ++++ +P+F
Sbjct: 58 -HFCGGSLISEDWVVTAAHC-GVRTSDVVVAG-EFDQGSDEENIQVLKIAKVFKNPKFSI 114
Query: 116 AQIGADIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPL 175
+ DI LL+L P S V V LP A + FP G C TGWG + P L
Sbjct: 115 LTVNNDITLLKLATPARFSQTVSAVCLPSADDDFPAGTLCATTGWGKTKYNANKTPD-KL 173
Query: 176 KQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLVCKVNGT 235
+Q +P++ N C + R + D M+CAG + SC GDSGGPLVC+ +G
Sbjct: 174 QQAALPLLSNAECKKSWG---------RRITDVMICAGASGVSSCMGDSGGPLVCQKDGA 224
Query: 236 WLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWI 267
W G+VSWG + PG+Y RVT + W+
Sbjct: 225 WTLVGIVSWGSDTCSTSSPGVYARVTKLIPWV 256
>gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo
sapiens]
Length = 529
Score = 164 bits (415), Expect = 8e-41
Identities = 94/263 (35%), Positives = 137/263 (52%), Gaps = 18/263 (6%)
Query: 11 VLASRAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVL 70
V++ R A + ++ IVGG+ A WPWQVSL V +H CGGS+I P+W++
Sbjct: 273 VVSLRCIACGVNLNSSRQSRIVGGESALPGAWPWQVSLHVQN---VHVCGGSIITPEWIV 329
Query: 71 TAAHCVGPDVKD---LAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLEL 127
TAAHCV + + A LR+ ++Y V ++I HP + + DIAL++L
Sbjct: 330 TAAHCVEKPLNNPWHWTAFAGILRQSFMFYGAGY-QVEKVISHPNYDSKTKNNDIALMKL 388
Query: 128 EEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHI 187
++P+ + V V LP P CW++GWG + E+ L KV ++E
Sbjct: 389 QKPLTFNDLVKPVCLPNPGMMLQPEQLCWISGWGATE--EKGKTSEVLNAAKVLLIETQR 446
Query: 188 CDAKYHLGAYTGDDVRIVRDDMLCAGNTRR--DSCQGDSGGPLVCKVNGTWLQAGVVSWG 245
C+++Y ++ M+CAG + DSCQGDSGGPLV N W G SWG
Sbjct: 447 CNSRYVYD-------NLITPAMICAGFLQGNVDSCQGDSGGPLVTSKNNIWWLIGDTSWG 499
Query: 246 EGCAQPNRPGIYTRVTYYLDWIH 268
GCA+ RPG+Y V + DWI+
Sbjct: 500 SGCAKAYRPGVYGNVMVFTDWIY 522
>gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo
sapiens]
Length = 492
Score = 164 bits (415), Expect = 8e-41
Identities = 94/263 (35%), Positives = 137/263 (52%), Gaps = 18/263 (6%)
Query: 11 VLASRAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVL 70
V++ R A + ++ IVGG+ A WPWQVSL V +H CGGS+I P+W++
Sbjct: 236 VVSLRCIACGVNLNSSRQSRIVGGESALPGAWPWQVSLHVQN---VHVCGGSIITPEWIV 292
Query: 71 TAAHCVGPDVKD---LAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLEL 127
TAAHCV + + A LR+ ++Y V ++I HP + + DIAL++L
Sbjct: 293 TAAHCVEKPLNNPWHWTAFAGILRQSFMFYGAGY-QVEKVISHPNYDSKTKNNDIALMKL 351
Query: 128 EEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHI 187
++P+ + V V LP P CW++GWG + E+ L KV ++E
Sbjct: 352 QKPLTFNDLVKPVCLPNPGMMLQPEQLCWISGWGATE--EKGKTSEVLNAAKVLLIETQR 409
Query: 188 CDAKYHLGAYTGDDVRIVRDDMLCAGNTRR--DSCQGDSGGPLVCKVNGTWLQAGVVSWG 245
C+++Y ++ M+CAG + DSCQGDSGGPLV N W G SWG
Sbjct: 410 CNSRYVYD-------NLITPAMICAGFLQGNVDSCQGDSGGPLVTSKNNIWWLIGDTSWG 462
Query: 246 EGCAQPNRPGIYTRVTYYLDWIH 268
GCA+ RPG+Y V + DWI+
Sbjct: 463 SGCAKAYRPGVYGNVMVFTDWIY 485
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.140 0.471
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,123,079
Number of Sequences: 37866
Number of extensions: 669225
Number of successful extensions: 2094
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 164
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 1397
Number of HSP's gapped (non-prelim): 196
length of query: 275
length of database: 18,247,518
effective HSP length: 101
effective length of query: 174
effective length of database: 14,423,052
effective search space: 2509611048
effective search space used: 2509611048
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.