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Search of human proteins with 6912724
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|6912724 tolloid-like 2 [Homo sapiens]
(1015 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|6912724 tolloid-like 2 [Homo sapiens] 2147 0.0
gi|5453579 bone morphogenetic protein 1 isoform 3 precursor [Hom... 1600 0.0
gi|22547221 tolloid-like 1 [Homo sapiens] 1590 0.0
gi|4502421 bone morphogenetic protein 1 isoform 1 precursor [Hom... 1125 0.0
gi|5902808 bone morphogenetic protein 1 isoform 2 precursor [Hom... 1121 0.0
gi|126091152 cubilin [Homo sapiens] 317 4e-86
gi|72384339 CUB domain containing protein 2 [Homo sapiens] 225 2e-58
gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens] 214 3e-55
gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo sap... 213 6e-55
gi|205277354 CUB and Sushi multiple domains 3 isoform 3 [Homo sa... 213 6e-55
gi|38045888 CUB and Sushi multiple domains 3 isoform 1 [Homo sap... 213 6e-55
gi|92110053 CUB and Sushi multiple domains 2 [Homo sapiens] 206 7e-53
gi|73623026 mannan-binding lectin serine protease 1 isoform 3 [H... 170 5e-42
gi|21264359 mannan-binding lectin serine protease 1 isoform 2 pr... 170 5e-42
gi|21264357 mannan-binding lectin serine protease 1 isoform 1 pr... 170 5e-42
gi|157653329 procollagen C-endopeptidase enhancer [Homo sapiens] 169 2e-41
gi|13899255 membrane frizzled-related protein [Homo sapiens] 166 1e-40
gi|7019483 procollagen C-endopeptidase enhancer 2 [Homo sapiens] 160 6e-39
gi|41872572 neuropilin 2 isoform 3 precursor [Homo sapiens] 155 2e-37
gi|41872567 neuropilin 2 isoform 5 precursor [Homo sapiens] 155 2e-37
gi|41872562 neuropilin 2 isoform 1 precursor [Homo sapiens] 155 2e-37
gi|41872557 neuropilin 2 isoform 6 precursor [Homo sapiens] 155 2e-37
gi|41872544 neuropilin 2 isoform 4 precursor [Homo sapiens] 155 2e-37
gi|41872533 neuropilin 2 isoform 2 precursor [Homo sapiens] 155 2e-37
gi|66347875 complement component 1, r subcomponent [Homo sapiens] 149 1e-35
gi|239755390 PREDICTED: similar to DMBT1 isoform 1 [Homo sapiens] 144 3e-34
gi|239755388 PREDICTED: similar to DMBT1 isoform 2 [Homo sapiens] 144 3e-34
gi|148539844 deleted in malignant brain tumors 1 isoform c precu... 144 3e-34
gi|148539842 deleted in malignant brain tumors 1 isoform b precu... 144 3e-34
gi|148539840 deleted in malignant brain tumors 1 isoform a precu... 144 3e-34
>gi|6912724 tolloid-like 2 [Homo sapiens]
Length = 1015
Score = 2147 bits (5564), Expect = 0.0
Identities = 1015/1015 (100%), Positives = 1015/1015 (100%)
Query: 1 MPRATALGALVSLLLLLPLPRGAGGLGERPDATADYSELDGEEGTEQQLEHYHDPCKAAV 60
MPRATALGALVSLLLLLPLPRGAGGLGERPDATADYSELDGEEGTEQQLEHYHDPCKAAV
Sbjct: 1 MPRATALGALVSLLLLLPLPRGAGGLGERPDATADYSELDGEEGTEQQLEHYHDPCKAAV 60
Query: 61 FWGDIALDEDDLKLFHIDKARDWTKQTVGATGHSTGGLEEQASESSPDTTAMDTGTKEAG 120
FWGDIALDEDDLKLFHIDKARDWTKQTVGATGHSTGGLEEQASESSPDTTAMDTGTKEAG
Sbjct: 61 FWGDIALDEDDLKLFHIDKARDWTKQTVGATGHSTGGLEEQASESSPDTTAMDTGTKEAG 120
Query: 121 KDGRENTTLLHSPGTLHAAAKTFSPRVRRATTSRTERIWPGGVIPYVIGGNFTGSQRAIF 180
KDGRENTTLLHSPGTLHAAAKTFSPRVRRATTSRTERIWPGGVIPYVIGGNFTGSQRAIF
Sbjct: 121 KDGRENTTLLHSPGTLHAAAKTFSPRVRRATTSRTERIWPGGVIPYVIGGNFTGSQRAIF 180
Query: 181 KQAMRHWEKHTCVTFIERTDEESFIVFSYRTCGCCSYVGRRGGGPQAISIGKNCDKFGIV 240
KQAMRHWEKHTCVTFIERTDEESFIVFSYRTCGCCSYVGRRGGGPQAISIGKNCDKFGIV
Sbjct: 181 KQAMRHWEKHTCVTFIERTDEESFIVFSYRTCGCCSYVGRRGGGPQAISIGKNCDKFGIV 240
Query: 241 AHELGHVVGFWHEHTRPDRDQHVTIIRENIQPGQEYNFLKMEAGEVSSLGETYDFDSIMH 300
AHELGHVVGFWHEHTRPDRDQHVTIIRENIQPGQEYNFLKMEAGEVSSLGETYDFDSIMH
Sbjct: 241 AHELGHVVGFWHEHTRPDRDQHVTIIRENIQPGQEYNFLKMEAGEVSSLGETYDFDSIMH 300
Query: 301 YARNTFSRGVFLDTILPRQDDNGVRPTIGQRVRLSQGDIAQARKLYKCPACGETLQDTTG 360
YARNTFSRGVFLDTILPRQDDNGVRPTIGQRVRLSQGDIAQARKLYKCPACGETLQDTTG
Sbjct: 301 YARNTFSRGVFLDTILPRQDDNGVRPTIGQRVRLSQGDIAQARKLYKCPACGETLQDTTG 360
Query: 361 NFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVEVRDGYWRKAP 420
NFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVEVRDGYWRKAP
Sbjct: 361 NFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVEVRDGYWRKAP 420
Query: 421 LLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEATCGGDMNKDAGQIQSPNY 480
LLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEATCGGDMNKDAGQIQSPNY
Sbjct: 421 LLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEATCGGDMNKDAGQIQSPNY 480
Query: 481 PDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDYLEVRDGPTEESALIGHFCG 540
PDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDYLEVRDGPTEESALIGHFCG
Sbjct: 481 PDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDYLEVRDGPTEESALIGHFCG 540
Query: 541 YEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECSWPDHGGCEHRCVNTLGSYK 600
YEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECSWPDHGGCEHRCVNTLGSYK
Sbjct: 541 YEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECSWPDHGGCEHRCVNTLGSYK 600
Query: 601 CACDPGYELAADKKMCEVACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISL 660
CACDPGYELAADKKMCEVACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISL
Sbjct: 601 CACDPGYELAADKKMCEVACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISL 660
Query: 661 QFEVFELEGNDVCKYDFVEVRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTV 720
QFEVFELEGNDVCKYDFVEVRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTV
Sbjct: 661 QFEVFELEGNDVCKYDFVEVRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTV 720
Query: 721 SKRGFRAHFFSDKDECAKDNGGCQHECVNTFGSYLCRCRNGYWLHENGHDCKEAGCAHKI 780
SKRGFRAHFFSDKDECAKDNGGCQHECVNTFGSYLCRCRNGYWLHENGHDCKEAGCAHKI
Sbjct: 721 SKRGFRAHFFSDKDECAKDNGGCQHECVNTFGSYLCRCRNGYWLHENGHDCKEAGCAHKI 780
Query: 781 SSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMYDGP 840
SSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMYDGP
Sbjct: 781 SSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMYDGP 840
Query: 841 DSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQAVHSTECGGRLKAEVQTK 900
DSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQAVHSTECGGRLKAEVQTK
Sbjct: 841 DSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQAVHSTECGGRLKAEVQTK 900
Query: 901 ELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGYDYMEAYDGYDSS 960
ELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGYDYMEAYDGYDSS
Sbjct: 901 ELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGYDYMEAYDGYDSS 960
Query: 961 APRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARYTSTKFQDALHMKK 1015
APRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARYTSTKFQDALHMKK
Sbjct: 961 APRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARYTSTKFQDALHMKK 1015
>gi|5453579 bone morphogenetic protein 1 isoform 3 precursor [Homo
sapiens]
Length = 986
Score = 1600 bits (4144), Expect = 0.0
Identities = 744/1015 (73%), Positives = 850/1015 (83%), Gaps = 29/1015 (2%)
Query: 1 MPRATALGALVSLLLLLPLPRGAGGLGERPDATADYSELDGEEGTEQQLEHYHDPCKAAV 60
MP L L+ LLLL PR RP ADY+ EE + L +Y DPCKAA
Sbjct: 1 MPGVARLPLLLGLLLL---PRPG-----RPLDLADYTYDLAEEDDSEPL-NYKDPCKAAA 51
Query: 61 FWGDIALDEDDLKLFHIDKARDWTKQTVGATGHSTGGLEEQASESSPDTTAMDTGTKEAG 120
F GDIALDE+DL+ F + +A D + T + ++ S T G + G
Sbjct: 52 FLGDIALDEEDLRAFQVQQAVDLRRHTARKSSIKAAVPGNTSTPSCQSTN----GQPQRG 107
Query: 121 KDGRENTTLLHSPGTLHAAAKTFSPRVRRATTSRTERIWPGGVIPYVIGGNFTGSQRAIF 180
GR R RRA TSR ER+WP GVIP+VIGGNFTGSQRA+F
Sbjct: 108 ACGRWRGR----------------SRSRRAATSRPERVWPDGVIPFVIGGNFTGSQRAVF 151
Query: 181 KQAMRHWEKHTCVTFIERTDEESFIVFSYRTCGCCSYVGRRGGGPQAISIGKNCDKFGIV 240
+QAMRHWEKHTCVTF+ERTDE+S+IVF+YR CGCCSYVGRRGGGPQAISIGKNCDKFGIV
Sbjct: 152 RQAMRHWEKHTCVTFLERTDEDSYIVFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGIV 211
Query: 241 AHELGHVVGFWHEHTRPDRDQHVTIIRENIQPGQEYNFLKMEAGEVSSLGETYDFDSIMH 300
HELGHVVGFWHEHTRPDRD+HV+I+RENIQPGQEYNFLKME EV SLGETYDFDSIMH
Sbjct: 212 VHELGHVVGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMEPQEVESLGETYDFDSIMH 271
Query: 301 YARNTFSRGVFLDTILPRQDDNGVRPTIGQRVRLSQGDIAQARKLYKCPACGETLQDTTG 360
YARNTFSRG+FLDTI+P+ + NGV+P IGQR RLS+GDIAQARKLYKCPACGETLQD+TG
Sbjct: 272 YARNTFSRGIFLDTIVPKYEVNGVKPPIGQRTRLSKGDIAQARKLYKCPACGETLQDSTG 331
Query: 361 NFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVEVRDGYWRKAP 420
NFS+P +PNGY ++ HCVWRISVTPGEKI+LNFTS+DL++SRLCWYDYVEVRDG+WRKAP
Sbjct: 332 NFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVEVRDGFWRKAP 391
Query: 421 LLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEATCGGDMNKDAGQIQSPNY 480
L GRFCG K+PEP+VSTDSRLWVEFRSSSN +GKGFFA YEA CGGD+ KD G IQSPNY
Sbjct: 392 LRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGGDVKKDYGHIQSPNY 451
Query: 481 PDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDYLEVRDGPTEESALIGHFCG 540
PDDYRPSK C+WRI VSEGFHVGLTFQ+FEIERHDSCAYDYLEVRDG +E S LIG +CG
Sbjct: 452 PDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGRYCG 511
Query: 541 YEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECSWPDHGGCEHRCVNTLGSYK 600
YEKP+D+KS+S+RLW+KFVSDGSINKAGFA NFFKEVDECS P+ GGCE RC+NTLGSYK
Sbjct: 512 YEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYK 571
Query: 601 CACDPGYELAADKKMCEVACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISL 660
C+CDPGYELA DK+ CE ACGGF+TKLNG+ITSPGWPKEYP NKNC+WQ+VAP QYRISL
Sbjct: 572 CSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISL 631
Query: 661 QFEVFELEGNDVCKYDFVEVRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTV 720
QF+ FE EGNDVCKYDFVEVRSGL+ D+KLHG+FCGSE PEVITSQ NNMRVEFKSDNTV
Sbjct: 632 QFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTV 691
Query: 721 SKRGFRAHFFSDKDECAKDNGGCQHECVNTFGSYLCRCRNGYWLHENGHDCKEAGCAHKI 780
SK+GF+AHFFSDKDEC+KDNGGCQ +CVNTFGSY C+CR+G+ LH+N HDCKEAGC HK+
Sbjct: 692 SKKGFKAHFFSDKDECSKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCDHKV 751
Query: 781 SSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMYDGP 840
+S GT+ SPNWPDKYPS++ECTW ISST GHRVKLTF E +IE ECAYDHLE++DG
Sbjct: 752 TSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVFDGR 811
Query: 841 DSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQAVHSTECGGRLKAEVQTK 900
D+ AP+LGRFCGSKKP+P +A+GS MFLRFYSD SVQRKGFQA H+TECGG+++A+V+TK
Sbjct: 812 DAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASHATECGGQVRADVKTK 871
Query: 901 ELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGYDYMEAYDGYDSS 960
+LYSHAQFGDNNYP C+WVIVAE+GYGVEL F+TFEVEEE DCGYDYME +DGYDS+
Sbjct: 872 DLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDST 931
Query: 961 APRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARYTSTKFQDALHMKK 1015
APRLGR+CGSGP EE+YSAGDS++++F +DDTI KKGFH RYTSTKFQD LH +K
Sbjct: 932 APRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTSTKFQDTLHSRK 986
>gi|22547221 tolloid-like 1 [Homo sapiens]
Length = 1013
Score = 1590 bits (4117), Expect = 0.0
Identities = 723/981 (73%), Positives = 830/981 (84%), Gaps = 1/981 (0%)
Query: 35 DYSELDGEEGTEQQLEHYHDPCKAAVFWGDIALDEDDLKLFHIDKARDWTKQTVGATGHS 94
DY+ DG E + + Y DPCKAAVFWGDIALD++DL +F ID+ D T+ G GH+
Sbjct: 34 DYT-FDGNEEDKTETIDYKDPCKAAVFWGDIALDDEDLNIFQIDRTIDLTQNPFGNLGHT 92
Query: 95 TGGLEEQASESSPDTTAMDTGTKEAGKDGRENTTLLHSPGTLHAAAKTFSPRVRRATTSR 154
TGGL + A G E + L + + RV RA TSR
Sbjct: 93 TGGLGDHAMSKKRGALYQLIDRIRRIGFGLEQNNTVKGKVPLQFSGQNEKNRVPRAATSR 152
Query: 155 TERIWPGGVIPYVIGGNFTGSQRAIFKQAMRHWEKHTCVTFIERTDEESFIVFSYRTCGC 214
TERIWPGGVIPYVIGGNFTGSQRA+FKQAMRHWEKHTCVTFIER+DEES+IVF+YR CGC
Sbjct: 153 TERIWPGGVIPYVIGGNFTGSQRAMFKQAMRHWEKHTCVTFIERSDEESYIVFTYRPCGC 212
Query: 215 CSYVGRRGGGPQAISIGKNCDKFGIVAHELGHVVGFWHEHTRPDRDQHVTIIRENIQPGQ 274
CSYVGRRG GPQAISIGKNCDKFGIV HELGHV+GFWHEHTRPDRD HVTIIRENIQPGQ
Sbjct: 213 CSYVGRRGNGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDNHVTIIRENIQPGQ 272
Query: 275 EYNFLKMEAGEVSSLGETYDFDSIMHYARNTFSRGVFLDTILPRQDDNGVRPTIGQRVRL 334
EYNFLKME GEV+SLGE YDFDSIMHYARNTFSRG+FLDTILP +DDNG+RP IGQR RL
Sbjct: 273 EYNFLKMEPGEVNSLGERYDFDSIMHYARNTFSRGMFLDTILPSRDDNGIRPAIGQRTRL 332
Query: 335 SQGDIAQARKLYKCPACGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFT 394
S+GDIAQARKLY+CPACGETLQ++ GN S+PGFPNGYPSY+HC+WR+SVTPGEKIVLNFT
Sbjct: 333 SKGDIAQARKLYRCPACGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFT 392
Query: 395 SMDLFKSRLCWYDYVEVRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGK 454
+MDL+KS LCWYDY+EVRDGYWRK+PLLGRFCGDK+PE L STDSR+W+EFRSSSN +GK
Sbjct: 393 TMDLYKSSLCWYDYIEVRDGYWRKSPLLGRFCGDKLPEVLTSTDSRMWIEFRSSSNWVGK 452
Query: 455 GFFAAYEATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERH 514
GF A YEA CGG++ K+ GQIQSPNYPDDYRP KECVW+ITVSE +HVGLTFQ+FEIERH
Sbjct: 453 GFAAVYEAICGGEIRKNEGQIQSPNYPDDYRPMKECVWKITVSESYHVGLTFQSFEIERH 512
Query: 515 DSCAYDYLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFF 574
D+CAYDYLEVRDG +E S LIG FCGY+KPED++S+SN LWMKFVSDG++NKAGFAANFF
Sbjct: 513 DNCAYDYLEVRDGTSENSPLIGRFCGYDKPEDIRSTSNTLWMKFVSDGTVNKAGFAANFF 572
Query: 575 KEVDECSWPDHGGCEHRCVNTLGSYKCACDPGYELAADKKMCEVACGGFITKLNGTITSP 634
KE DEC+ PD GGCE RC+NTLGSY+CAC+PGYEL D++ CE ACGG +TKLNGTIT+P
Sbjct: 573 KEEDECAKPDRGGCEQRCLNTLGSYQCACEPGYELGPDRRSCEAACGGLLTKLNGTITTP 632
Query: 635 GWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVEVRSGLSPDAKLHGRF 694
GWPKEYP NKNCVWQVVAP QYRIS++FE FELEGN+VCKYD+VE+ SGLS ++KLHG+F
Sbjct: 633 GWPKEYPPNKNCVWQVVAPTQYRISVKFEFFELEGNEVCKYDYVEIWSGLSSESKLHGKF 692
Query: 695 CGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECAKDNGGCQHECVNTFGSY 754
CG+E PEVITSQ NNMR+EFKSDNTVSK+GF+AHFFSDKDEC+KDNGGCQHECVNT GSY
Sbjct: 693 CGAEVPEVITSQFNNMRIEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQHECVNTMGSY 752
Query: 755 LCRCRNGYWLHENGHDCKEAGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRV 814
+C+CRNG+ LH+N HDCKEA C KI S G + SPNWPDKYPSR+ECTW IS+T GHR+
Sbjct: 753 MCQCRNGFVLHDNKHDCKEAECEQKIHSPSGLITSPNWPDKYPSRKECTWEISATPGHRI 812
Query: 815 KLTFNEFEIEQHQECAYDHLEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDA 874
KL F+EFEIEQHQECAYDHLE++DG +PILGR CG+K PDP VA+G+ MF+RF SDA
Sbjct: 813 KLAFSEFEIEQHQECAYDHLEVFDGETEKSPILGRLCGNKIPDPLVATGNKMFVRFVSDA 872
Query: 875 SVQRKGFQAVHSTECGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELT 934
SVQRKGFQA HSTECGGRLKAE + ++LYSHAQFGDNNYP + C+W++V+E G +EL+
Sbjct: 873 SVQRKGFQATHSTECGGRLKAESKPRDLYSHAQFGDNNYPGQVDCEWLLVSERGSRLELS 932
Query: 935 FRTFEVEEEADCGYDYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTIN 994
F+TFEVEEEADCGYDY+E +DG DS+A LGRFCGSGP EEIYS GDS++I F TDDTIN
Sbjct: 933 FQTFEVEEEADCGYDYVELFDGLDSTAVGLGRFCGSGPPEEIYSIGDSVLIHFHTDDTIN 992
Query: 995 KKGFHARYTSTKFQDALHMKK 1015
KKGFH RY S ++ D H KK
Sbjct: 993 KKGFHIRYKSIRYPDTTHTKK 1013
>gi|4502421 bone morphogenetic protein 1 isoform 1 precursor [Homo
sapiens]
Length = 730
Score = 1125 bits (2909), Expect = 0.0
Identities = 536/746 (71%), Positives = 606/746 (81%), Gaps = 29/746 (3%)
Query: 1 MPRATALGALVSLLLLLPLPRGAGGLGERPDATADYSELDGEEGTEQQLEHYHDPCKAAV 60
MP L L+ LLLL PR RP ADY+ EE + L +Y DPCKAA
Sbjct: 1 MPGVARLPLLLGLLLL---PRPG-----RPLDLADYTYDLAEEDDSEPL-NYKDPCKAAA 51
Query: 61 FWGDIALDEDDLKLFHIDKARDWTKQTVGATGHSTGGLEEQASESSPDTTAMDTGTKEAG 120
F GDIALDE+DL+ F + +A D + T + ++ S T G + G
Sbjct: 52 FLGDIALDEEDLRAFQVQQAVDLRRHTARKSSIKAAVPGNTSTPSCQSTN----GQPQRG 107
Query: 121 KDGRENTTLLHSPGTLHAAAKTFSPRVRRATTSRTERIWPGGVIPYVIGGNFTGSQRAIF 180
GR R RRA TSR ER+WP GVIP+VIGGNFTGSQRA+F
Sbjct: 108 ACGRWRGR----------------SRSRRAATSRPERVWPDGVIPFVIGGNFTGSQRAVF 151
Query: 181 KQAMRHWEKHTCVTFIERTDEESFIVFSYRTCGCCSYVGRRGGGPQAISIGKNCDKFGIV 240
+QAMRHWEKHTCVTF+ERTDE+S+IVF+YR CGCCSYVGRRGGGPQAISIGKNCDKFGIV
Sbjct: 152 RQAMRHWEKHTCVTFLERTDEDSYIVFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGIV 211
Query: 241 AHELGHVVGFWHEHTRPDRDQHVTIIRENIQPGQEYNFLKMEAGEVSSLGETYDFDSIMH 300
HELGHVVGFWHEHTRPDRD+HV+I+RENIQPGQEYNFLKME EV SLGETYDFDSIMH
Sbjct: 212 VHELGHVVGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMEPQEVESLGETYDFDSIMH 271
Query: 301 YARNTFSRGVFLDTILPRQDDNGVRPTIGQRVRLSQGDIAQARKLYKCPACGETLQDTTG 360
YARNTFSRG+FLDTI+P+ + NGV+P IGQR RLS+GDIAQARKLYKCPACGETLQD+TG
Sbjct: 272 YARNTFSRGIFLDTIVPKYEVNGVKPPIGQRTRLSKGDIAQARKLYKCPACGETLQDSTG 331
Query: 361 NFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVEVRDGYWRKAP 420
NFS+P +PNGY ++ HCVWRISVTPGEKI+LNFTS+DL++SRLCWYDYVEVRDG+WRKAP
Sbjct: 332 NFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVEVRDGFWRKAP 391
Query: 421 LLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEATCGGDMNKDAGQIQSPNY 480
L GRFCG K+PEP+VSTDSRLWVEFRSSSN +GKGFFA YEA CGGD+ KD G IQSPNY
Sbjct: 392 LRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGGDVKKDYGHIQSPNY 451
Query: 481 PDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDYLEVRDGPTEESALIGHFCG 540
PDDYRPSK C+WRI VSEGFHVGLTFQ+FEIERHDSCAYDYLEVRDG +E S LIG +CG
Sbjct: 452 PDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGRYCG 511
Query: 541 YEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECSWPDHGGCEHRCVNTLGSYK 600
YEKP+D+KS+S+RLW+KFVSDGSINKAGFA NFFKEVDECS P+ GGCE RC+NTLGSYK
Sbjct: 512 YEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYK 571
Query: 601 CACDPGYELAADKKMCEVACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISL 660
C+CDPGYELA DK+ CE ACGGF+TKLNG+ITSPGWPKEYP NKNC+WQ+VAP QYRISL
Sbjct: 572 CSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISL 631
Query: 661 QFEVFELEGNDVCKYDFVEVRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTV 720
QF+ FE EGNDVCKYDFVEVRSGL+ D+KLHG+FCGSE PEVITSQ NNMRVEFKSDNTV
Sbjct: 632 QFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTV 691
Query: 721 SKRGFRAHFFSDKDECAKDNGGCQHE 746
SK+GF+AHFFS+K + G H+
Sbjct: 692 SKKGFKAHFFSEKRPALQPPRGRPHQ 717
Score = 292 bits (748), Expect = 1e-78
Identities = 147/421 (34%), Positives = 225/421 (53%), Gaps = 45/421 (10%)
Query: 464 CGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDYLE 523
CG + G SP YP+ Y CVWRI+V+ G + L F + ++ R C YDY+E
Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
Query: 524 VRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECSWP 583
VRDG ++ L G FCG + PE + S+ +RLW++F S + GF A +
Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVY---------- 431
Query: 584 DHGGCEHRCVNTLGSYKCACDPGYELAADKKMCEVACGGFITKLNGTITSPGWPKEYPTN 643
E CGG + K G I SP +P +Y +
Sbjct: 432 ---------------------------------EAICGGDVKKDYGHIQSPNYPDDYRPS 458
Query: 644 KNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVEVRSGLSPDAKLHGRFCGSETPEVI 703
K C+W++ + + L F+ FE+E +D C YD++EVR G S + L GR+CG E P+ I
Sbjct: 459 KVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDI 518
Query: 704 TSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECAKDN-GGCQHECVNTFGSYLCRCRNGY 762
S S+ + ++F SD +++K GF +FF + DEC++ N GGC+ C+NT GSY C C GY
Sbjct: 519 KSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGY 578
Query: 763 WLHENGHDCKEAGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFE 822
L + C EA C ++ + G++ SP WP +YP + C W + + +R+ L F+ FE
Sbjct: 579 ELAPDKRRC-EAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFE 637
Query: 823 IEQHQECAYDHLEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQ 882
E + C YD +E+ G + + + G+FCGS+KP+ + ++M + F SD +V +KGF+
Sbjct: 638 TEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFK 697
Query: 883 A 883
A
Sbjct: 698 A 698
Score = 209 bits (533), Expect = 8e-54
Identities = 128/427 (29%), Positives = 188/427 (44%), Gaps = 82/427 (19%)
Query: 619 ACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFV 678
ACG + G +SP +P Y + +CVW++ +I L F +L + +C YD+V
Sbjct: 321 ACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYV 380
Query: 679 EVRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECAK 738
EVR G A L GRFCGS+ PE I S + + VEF+S + +GF A +
Sbjct: 381 EVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVY--------- 431
Query: 739 DNGGCQHECVNTFGSYLCRCRNGYWLHENGHDCKEAGCAHKISSVEGTLASPNWPDKYPS 798
EA C + G + SPN+PD Y
Sbjct: 432 ----------------------------------EAICGGDVKKDYGHIQSPNYPDDYRP 457
Query: 799 RRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMYDGPDSLAPILGRFCGSKKPDP 858
+ C W I + G V LTF FEIE+H CAYD+LE+ DG + ++GR+CG +KPD
Sbjct: 458 SKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDD 517
Query: 859 TVASGSSMFLRFYSDASVQRKGF------------------------QAVHSTECGGRLK 894
++ S ++L+F SD S+ + GF + S +C
Sbjct: 518 IKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPG 577
Query: 895 AEVQTKELYSHAQFGD---------------NNYPSEARCDWVIVAEDGYGVELTFRTFE 939
E+ + A G YP C W +VA Y + L F FE
Sbjct: 578 YELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFE 637
Query: 940 VEEEADCGYDYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFH 999
E C YD++E G + + G+FCGS E I S +++ + F++D+T++KKGF
Sbjct: 638 TEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFK 697
Query: 1000 ARYTSTK 1006
A + S K
Sbjct: 698 AHFFSEK 704
>gi|5902808 bone morphogenetic protein 1 isoform 2 precursor [Homo
sapiens]
Length = 823
Score = 1121 bits (2899), Expect = 0.0
Identities = 537/756 (71%), Positives = 608/756 (80%), Gaps = 34/756 (4%)
Query: 1 MPRATALGALVSLLLLLPLPRGAGGLGERPDATADYSELDGEEGTEQQLEHYHDPCKAAV 60
MP L L+ LLLL PR RP ADY+ EE + L +Y DPCKAA
Sbjct: 1 MPGVARLPLLLGLLLL---PRPG-----RPLDLADYTYDLAEEDDSEPL-NYKDPCKAAA 51
Query: 61 FWGDIALDEDDLKLFHIDKARDWTKQTVGATGHSTGGLEEQASESSPDTTAMDTGTKEAG 120
F GDIALDE+DL+ F + +A D + T + ++ S T G + G
Sbjct: 52 FLGDIALDEEDLRAFQVQQAVDLRRHTARKSSIKAAVPGNTSTPSCQSTN----GQPQRG 107
Query: 121 KDGRENTTLLHSPGTLHAAAKTFSPRVRRATTSRTERIWPGGVIPYVIGGNFTGSQRAIF 180
GR R RRA TSR ER+WP GVIP+VIGGNFTGSQRA+F
Sbjct: 108 ACGRWRGR----------------SRSRRAATSRPERVWPDGVIPFVIGGNFTGSQRAVF 151
Query: 181 KQAMRHWEKHTCVTFIERTDEESFIVFSYRTCGCCSYVGRRGGGPQAISIGKNCDKFGIV 240
+QAMRHWEKHTCVTF+ERTDE+S+IVF+YR CGCCSYVGRRGGGPQAISIGKNCDKFGIV
Sbjct: 152 RQAMRHWEKHTCVTFLERTDEDSYIVFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGIV 211
Query: 241 AHELGHVVGFWHEHTRPDRDQHVTIIRENIQPGQEYNFLKMEAGEVSSLGETYDFDSIMH 300
HELGHVVGFWHEHTRPDRD+HV+I+RENIQPGQEYNFLKME EV SLGETYDFDSIMH
Sbjct: 212 VHELGHVVGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMEPQEVESLGETYDFDSIMH 271
Query: 301 YARNTFSRGVFLDTILPRQDDNGVRPTIGQRVRLSQGDIAQARKLYKCPACGETLQDTTG 360
YARNTFSRG+FLDTI+P+ + NGV+P IGQR RLS+GDIAQARKLYKCPACGETLQD+TG
Sbjct: 272 YARNTFSRGIFLDTIVPKYEVNGVKPPIGQRTRLSKGDIAQARKLYKCPACGETLQDSTG 331
Query: 361 NFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVEVRDGYWRKAP 420
NFS+P +PNGY ++ HCVWRISVTPGEKI+LNFTS+DL++SRLCWYDYVEVRDG+WRKAP
Sbjct: 332 NFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVEVRDGFWRKAP 391
Query: 421 LLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEATCGGDMNKDAGQIQSPNY 480
L GRFCG K+PEP+VSTDSRLWVEFRSSSN +GKGFFA YEA CGGD+ KD G IQSPNY
Sbjct: 392 LRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGGDVKKDYGHIQSPNY 451
Query: 481 PDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDYLEVRDGPTEESALIGHFCG 540
PDDYRPSK C+WRI VSEGFHVGLTFQ+FEIERHDSCAYDYLEVRDG +E S LIG +CG
Sbjct: 452 PDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGRYCG 511
Query: 541 YEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECSWPDHGGCEHRCVNTLGSYK 600
YEKP+D+KS+S+RLW+KFVSDGSINKAGFA NFFKEVDECS P+ GGCE RC+NTLGSYK
Sbjct: 512 YEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYK 571
Query: 601 CACDPGYELAADKKMCEVACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISL 660
C+CDPGYELA DK+ CE ACGGF+TKLNG+ITSPGWPKEYP NKNC+WQ+VAP QYRISL
Sbjct: 572 CSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISL 631
Query: 661 QFEVFELEGNDVCKYDFVEVRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTV 720
QF+ FE EGNDVCKYDFVEVRSGL+ D+KLHG+FCGSE PEVITSQ NNMRVEFKSDNTV
Sbjct: 632 QFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTV 691
Query: 721 SKRGFRAHFFSDKDECAKDNGGCQHECVNTFGSYLC 756
SK+GF+AHFFS + G +H ++ LC
Sbjct: 692 SKKGFKAHFFS-----VLEGAGDRHSHLSGLELLLC 722
Score = 292 bits (748), Expect = 1e-78
Identities = 147/421 (34%), Positives = 225/421 (53%), Gaps = 45/421 (10%)
Query: 464 CGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDYLE 523
CG + G SP YP+ Y CVWRI+V+ G + L F + ++ R C YDY+E
Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
Query: 524 VRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECSWP 583
VRDG ++ L G FCG + PE + S+ +RLW++F S + GF A +
Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVY---------- 431
Query: 584 DHGGCEHRCVNTLGSYKCACDPGYELAADKKMCEVACGGFITKLNGTITSPGWPKEYPTN 643
E CGG + K G I SP +P +Y +
Sbjct: 432 ---------------------------------EAICGGDVKKDYGHIQSPNYPDDYRPS 458
Query: 644 KNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVEVRSGLSPDAKLHGRFCGSETPEVI 703
K C+W++ + + L F+ FE+E +D C YD++EVR G S + L GR+CG E P+ I
Sbjct: 459 KVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDI 518
Query: 704 TSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECAKDN-GGCQHECVNTFGSYLCRCRNGY 762
S S+ + ++F SD +++K GF +FF + DEC++ N GGC+ C+NT GSY C C GY
Sbjct: 519 KSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGY 578
Query: 763 WLHENGHDCKEAGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFE 822
L + C EA C ++ + G++ SP WP +YP + C W + + +R+ L F+ FE
Sbjct: 579 ELAPDKRRC-EAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFE 637
Query: 823 IEQHQECAYDHLEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQ 882
E + C YD +E+ G + + + G+FCGS+KP+ + ++M + F SD +V +KGF+
Sbjct: 638 TEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFK 697
Query: 883 A 883
A
Sbjct: 698 A 698
Score = 208 bits (529), Expect = 2e-53
Identities = 127/425 (29%), Positives = 187/425 (44%), Gaps = 82/425 (19%)
Query: 619 ACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFV 678
ACG + G +SP +P Y + +CVW++ +I L F +L + +C YD+V
Sbjct: 321 ACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYV 380
Query: 679 EVRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECAK 738
EVR G A L GRFCGS+ PE I S + + VEF+S + +GF A +
Sbjct: 381 EVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVY--------- 431
Query: 739 DNGGCQHECVNTFGSYLCRCRNGYWLHENGHDCKEAGCAHKISSVEGTLASPNWPDKYPS 798
EA C + G + SPN+PD Y
Sbjct: 432 ----------------------------------EAICGGDVKKDYGHIQSPNYPDDYRP 457
Query: 799 RRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMYDGPDSLAPILGRFCGSKKPDP 858
+ C W I + G V LTF FEIE+H CAYD+LE+ DG + ++GR+CG +KPD
Sbjct: 458 SKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDD 517
Query: 859 TVASGSSMFLRFYSDASVQRKGF------------------------QAVHSTECGGRLK 894
++ S ++L+F SD S+ + GF + S +C
Sbjct: 518 IKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPG 577
Query: 895 AEVQTKELYSHAQFGD---------------NNYPSEARCDWVIVAEDGYGVELTFRTFE 939
E+ + A G YP C W +VA Y + L F FE
Sbjct: 578 YELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFE 637
Query: 940 VEEEADCGYDYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFH 999
E C YD++E G + + G+FCGS E I S +++ + F++D+T++KKGF
Sbjct: 638 TEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFK 697
Query: 1000 ARYTS 1004
A + S
Sbjct: 698 AHFFS 702
>gi|126091152 cubilin [Homo sapiens]
Length = 3623
Score = 317 bits (812), Expect = 4e-86
Identities = 196/683 (28%), Positives = 326/683 (47%), Gaps = 115/683 (16%)
Query: 336 QGDIAQARKLYKCPACGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTS 395
+G + + AC + D G F++P FPN YP+ C++RI+V G+ I ++FT+
Sbjct: 1033 EGFLINYEAISAATACLQDYTDDLGTFTSPNFPNNYPNNWECIYRITVRTGQLIAVHFTN 1092
Query: 396 MDLFKSRLCWY-DYVEVRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGK 454
L ++ +Y D++E+RDG + K+PLLG F G +P ++S ++LW++F+S
Sbjct: 1093 FSLEEAIGNYYTDFLEIRDGGYEKSPLLGIFYGSNLPPTIISHSNKLWLKFKSDQIDTRS 1152
Query: 455 GFFAAYEAT---CGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEI 511
GF A ++ + CGG++ +G SPNYP Y S EC W + S G L F+ F +
Sbjct: 1153 GFSAYWDGSSTGCGGNLTTSSGTFISPNYPMPYYHSSECYWWLKSSHGSAFELEFKDFHL 1212
Query: 512 ERHDSCAYDYLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAA 571
E H +C DYL V DGP+ S L+ CG EKP ++SS + +++K +D GF A
Sbjct: 1213 EHHPNCTLDYLAVYDGPSSNSHLLTQLCGDEKPPLIRSSGDSMFIKLRTDEGQQGRGFKA 1272
Query: 572 NFFKEVDECSWPDHGGCEHRCVNTLGSYKCACDPGYELAADKKMCEVACGGFITKLNGTI 631
+ C N + + + G +
Sbjct: 1273 EY---------------RQTCENVV--------------------------IVNQTYGIL 1291
Query: 632 TSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVEVRSGLSPDAKLH 691
S G+P Y N++C W + A ++ F F+LE + C D++E+ G +
Sbjct: 1292 ESIGYPNPYSENQHCNWTIRATTGNTVNYTFLAFDLEHHINCSTDYLELYDG----PRQM 1347
Query: 692 GRFCGSETPEVITSQSNNMRVEFKSDNTVSK-RGFRAHFFSDKDECAKDNGGCQHECVNT 750
GR+CG + P ++ S+ ++V +D + +GF+ +F
Sbjct: 1348 GRYCGVDLPPPGSTTSSKLQVLLLTDGVGRREKGFQMQWF-------------------- 1387
Query: 751 FGSYLCRCRNGYWLHENGHDCKEAGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTA 810
GC ++S G+ +SP +P++YP +EC W I +
Sbjct: 1388 ----------------------VYGCGGELSGATGSFSSPGFPNRYPPNKECIWYIRTDP 1425
Query: 811 GHRVKLTFNEFEIEQHQECAYDHLEMYDGPDSLAPILGRFCGSKKPDPTV---ASGSSMF 867
G ++LT ++F++E H C +D LE+Y GPD +P + + C + P+ + ++G+ +
Sbjct: 1426 GSSIQLTIHDFDVEYHSRCNFDVLEIYGGPDFHSPRIAQLCTQRSPENPMQVSSTGNELA 1485
Query: 868 LRFYSDASVQRKGFQA---VHSTECGGRLKAEVQTKELYSHAQFGDNNYPSEAR----CD 920
+RF +D S+ +GF A + CGG +A + E++S NYPS R C
Sbjct: 1486 IRFKTDLSINGRGFNASWQAVTGGCGGIFQA--PSGEIHS------PNYPSPYRSNTDCS 1537
Query: 921 WVIVAEDGYGVELTFRTFEVEEEADCGYDYMEAYDGYDSSAPRLGRFCGSGPL-EEIYSA 979
WVI + + V L F F++E + C + AYDG S+ RL R CG L I S+
Sbjct: 1538 WVIRVDRNHRVLLNFTDFDLEPQDSC----IMAYDGLSSTMSRLARTCGREQLANPIVSS 1593
Query: 980 GDSLMIRFRTDDTINKKGFHARY 1002
G+SL +RF++ + +GF A++
Sbjct: 1594 GNSLFLRFQSGPSRQNRGFRAQF 1616
Score = 315 bits (808), Expect = 1e-85
Identities = 208/664 (31%), Positives = 305/664 (45%), Gaps = 102/664 (15%)
Query: 350 ACGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYV 409
ACGE L ++TG +PG PN YP +C W I V P I L F + L C DY+
Sbjct: 931 ACGEILTESTGTIQSPGHPNVYPHGINCTWHILVQPNHLIHLMFETFHLEFHYNCTNDYL 990
Query: 410 EVRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEA-----TC 464
EV D + LGR+CG IP L S+ + L + F + S++ +GF YEA C
Sbjct: 991 EVYDTDSETS--LGRYCGKSIPPSLTSSGNSLMLVFVTDSDLAYEGFLINYEAISAATAC 1048
Query: 465 GGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAY-DYLE 523
D D G SPN+P++Y + EC++RITV G + + F F +E Y D+LE
Sbjct: 1049 LQDYTDDLGTFTSPNFPNNYPNNWECIYRITVRTGQLIAVHFTNFSLEEAIGNYYTDFLE 1108
Query: 524 VRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECSWP 583
+RDG E+S L+G F G P + S SN+LW+KF SD ++GF+A W
Sbjct: 1109 IRDGGYEKSPLLGIFYGSNLPPTIISHSNKLWLKFKSDQIDTRSGFSA---------YWD 1159
Query: 584 DHGGCEHRCVNTLGSYKCACDPGYELAADKKMCEVACGGFITKLNGTITSPGWPKEYPTN 643
GS CGG +T +GT SP +P Y +
Sbjct: 1160 -------------GS------------------STGCGGNLTTSSGTFISPNYPMPYYHS 1188
Query: 644 KNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVEVRSGLSPDAKLHGRFCGSETPEVI 703
C W + + L+F+ F LE + C D++ V G S ++ L + CG E P +I
Sbjct: 1189 SECYWWLKSSHGSAFELEFKDFHLEHHPNCTLDYLAVYDGPSSNSHLLTQLCGDEKPPLI 1248
Query: 704 TSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECAKDNGGCQHECVNTFGSYLCRCRNGYW 763
S ++M ++ ++D RGF+A + + C N
Sbjct: 1249 RSSGDSMFIKLRTDEGQQGRGFKAEY--------------RQTCENVV------------ 1282
Query: 764 LHENGHDCKEAGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEI 823
++ G L S +P+ Y + C W I +T G+ V TF F++
Sbjct: 1283 ---------------IVNQTYGILESIGYPNPYSENQHCNWTIRATTGNTVNYTFLAFDL 1327
Query: 824 EQHQECAYDHLEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQR-KGFQ 882
E H C+ D+LE+YDGP +GR+CG P P + S + + +D +R KGFQ
Sbjct: 1328 EHHINCSTDYLELYDGPRQ----MGRYCGVDLPPPGSTTSSKLQVLLLTDGVGRREKGFQ 1383
Query: 883 AVHST-ECGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVE 941
CGG L + +S F N YP C W I + G ++LT F+VE
Sbjct: 1384 MQWFVYGCGGELSGATGS---FSSPGF-PNRYPPNKECIWYIRTDPGSSIQLTIHDFDVE 1439
Query: 942 EEADCGYDYMEAYDGYDSSAPRLGRFCGSGPLE---EIYSAGDSLMIRFRTDDTINKKGF 998
+ C +D +E Y G D +PR+ + C E ++ S G+ L IRF+TD +IN +GF
Sbjct: 1440 YHSRCNFDVLEIYGGPDFHSPRIAQLCTQRSPENPMQVSSTGNELAIRFKTDLSINGRGF 1499
Query: 999 HARY 1002
+A +
Sbjct: 1500 NASW 1503
Score = 307 bits (787), Expect = 3e-83
Identities = 209/687 (30%), Positives = 314/687 (45%), Gaps = 100/687 (14%)
Query: 333 RLSQGDIAQARKLYKCPACG-ETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPG-EKIV 390
R ++G AQ R+ ACG L + S+P FP YP+ +C W I P I
Sbjct: 1607 RQNRGFRAQFRQ-----ACGGHILTSSFDTVSSPRFPANYPNNQNCSWIIQAQPPLNHIT 1661
Query: 391 LNFTSMDLFKSRLCWYDYVEVRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSN 450
L+FT +L +S C D+VE+ DG APL GR+CG +P P+ S S L + F S S+
Sbjct: 1662 LSFTHFELERSTTCARDFVEILDGGHEDAPLRGRYCGTDMPHPITSFSSALTLRFVSDSS 1721
Query: 451 ILGKGFFAAYEAT---CGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQ 507
I GF A+ CGG G SP YPD Y P+ ECVW I S G + L+F
Sbjct: 1722 ISAGGFHTTVTASVSACGGTFYMAEGIFNSPGYPDIYPPNVECVWNIVSSPGNRLQLSFI 1781
Query: 508 AFEIERHDSCAYDYLEVRDGPTEESALIGHFCGYEKPEDVKS-SSNRLWMKFVSDGSINK 566
+F++E C+ D++E+R+G L+G +CG P + S + LW++F+SDGS +
Sbjct: 1782 SFQLEDSQDCSRDFVEIREG-NATGHLVGRYCGNSFPLNYSSIVGHTLWVRFISDGSGSG 1840
Query: 567 AGFAANFFKEVDECSWPDHGGCEHRCVNTLGSYKCACDPGYELAADKKMCEVACGGFITK 626
GF A F K + I
Sbjct: 1841 TGFQATFMK------------------------------------------IFGNDNIVG 1858
Query: 627 LNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVEVRSGLSP 686
+G + SP WP+ YP N N W V A + + + ++E C YD + + G S
Sbjct: 1859 THGKVASPFWPENYPHNSNYQWTVNVNASHVVHGRILEMDIEEIQNCYYDKLRIYDGPSI 1918
Query: 687 DAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECAKDNGGCQHE 746
A+L G +CG++T E +S N++ F SD+++S +GF +F+ +G
Sbjct: 1919 HARLIGAYCGTQT-ESFSSTGNSLTFHFYSDSSISGKGFLLEWFA----VDAPDGVLPTI 1973
Query: 747 CVNTFGSYLCRCRNGYWLHENGHDCKEAGCAHKISSVEGTLASPNWPDKYPSRRECTWNI 806
G +L + L SP WPD Y +R +CTW I
Sbjct: 1974 APGACGGFL-----------------------RTGDAPVFLFSPGWPDSYSNRVDCTWLI 2010
Query: 807 SSTAGHRVKLTFNEFEIEQHQECAYDHLEMYDGPDSLAPILGRFCGSKKPDPTVASGSSM 866
+ V+L +IE H+ CAYD L + DG ++LA L CG + P P ++G M
Sbjct: 2011 QA-PDSTVELNILSLDIESHRTCAYDSLVIRDGDNNLAQQLAVLCGREIPGPIRSTGEYM 2069
Query: 867 FLRFYSDASVQRKGFQAVHSTECGGRLKAE--VQTKELYSHAQFGDNNYPSEARCDWVIV 924
F+RF SD+SV R GF A CGG L A+ + T Y YPS C W ++
Sbjct: 2070 FIRFTSDSSVTRAGFNASFHKSCGGYLHADRGIITSPKY------PETYPSNLNCSWHVL 2123
Query: 925 AEDGYGVELTF-RTFEVEE-EADCGY-DYMEAYDGYDSSAPRL------GRFCGSGPLEE 975
+ G + + F + F++ ++ C DY+ +G D +P L G FCGS
Sbjct: 2124 VQSGLTIAVHFEQPFQIPNGDSSCNQGDYLVLRNGPDICSPPLGPPGGNGHFCGSHASST 2183
Query: 976 IYSAGDSLMIRFRTDDTINKKGFHARY 1002
++++ + + ++F +D + +GF +Y
Sbjct: 2184 LFTSDNQMFVQFISDHSNEGQGFKIKY 2210
Score = 300 bits (769), Expect = 4e-81
Identities = 190/663 (28%), Positives = 296/663 (44%), Gaps = 101/663 (15%)
Query: 351 CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVE 410
CG L ++G F +P +P Y S C W + + G L F L C DY+
Sbjct: 1165 CGGNLTTSSGTFISPNYPMPYYHSSECYWWLKSSHGSAFELEFKDFHLEHHPNCTLDYLA 1224
Query: 411 VRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEATCGGDM-- 468
V DG + LL + CGD+ P + S+ ++++ R+ G+GF A Y TC +
Sbjct: 1225 VYDGPSSNSHLLTQLCGDEKPPLIRSSGDSMFIKLRTDEGQQGRGFKAEYRQTCENVVIV 1284
Query: 469 NKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDYLEVRDGP 528
N+ G ++S YP+ Y ++ C W I + G V TF AF++E H +C+ DYLE+ DGP
Sbjct: 1285 NQTYGILESIGYPNPYSENQHCNWTIRATTGNTVNYTFLAFDLEHHINCSTDYLELYDGP 1344
Query: 529 TEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDG-SINKAGFAANFFKEVDECSWPDHGG 587
+ +G +CG + P ++S++L + ++DG + GF +F
Sbjct: 1345 RQ----MGRYCGVDLPPPGSTTSSKLQVLLLTDGVGRREKGFQMQWFV------------ 1388
Query: 588 CEHRCVNTLGSYKCACDPGYELAADKKMCEVACGGFITKLNGTITSPGWPKEYPTNKNCV 647
CGG ++ G+ +SPG+P YP NK C+
Sbjct: 1389 ------------------------------YGCGGELSGATGSFSSPGFPNRYPPNKECI 1418
Query: 648 WQVVAPAQYRISLQFEVFELEGNDVCKYDFVEVRSGLSPDAKLHGRFCGSETPE---VIT 704
W + I L F++E + C +D +E+ G + + C +PE ++
Sbjct: 1419 WYIRTDPGSSIQLTIHDFDVEYHSRCNFDVLEIYGGPDFHSPRIAQLCTQRSPENPMQVS 1478
Query: 705 SQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECAKDNGGCQHECVNTFGSYLCRCRNGYWL 764
S N + + FK+D +++ RGF N W
Sbjct: 1479 STGNELAIRFKTDLSINGRGF----------------------------------NASWQ 1504
Query: 765 HENGHDCKEAGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIE 824
G GC + G + SPN+P Y S +C+W I HRV L F +F++E
Sbjct: 1505 AVTG------GCGGIFQAPSGEIHSPNYPSPYRSNTDCSWVIRVDRNHRVLLNFTDFDLE 1558
Query: 825 QHQECAYDHLEMYDGPDSLAPILGRFCGSKK-PDPTVASGSSMFLRFYSDASVQRKGFQA 883
C + YDG S L R CG ++ +P V+SG+S+FLRF S S Q +GF+A
Sbjct: 1559 PQDSC----IMAYDGLSSTMSRLARTCGREQLANPIVSSGNSLFLRFQSGPSRQNRGFRA 1614
Query: 884 VHSTECGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYG-VELTFRTFEVEE 942
CGG + + + S +F NYP+ C W+I A+ + L+F FE+E
Sbjct: 1615 QFRQACGGHILTS--SFDTVSSPRF-PANYPNNQNCSWIIQAQPPLNHITLSFTHFELER 1671
Query: 943 EADCGYDYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARY 1002
C D++E DG AP GR+CG+ I S +L +RF +D +I+ GFH
Sbjct: 1672 STTCARDFVEILDGGHEDAPLRGRYCGTDMPHPITSFSSALTLRFVSDSSISAGGFHTTV 1731
Query: 1003 TST 1005
T++
Sbjct: 1732 TAS 1734
Score = 298 bits (763), Expect = 2e-80
Identities = 197/670 (29%), Positives = 297/670 (44%), Gaps = 109/670 (16%)
Query: 351 CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVE 410
CG Q +G +P +P+ Y S + C W I V +++LNFT DL C Y
Sbjct: 1510 CGGIFQAPSGEIHSPNYPSPYRSNTDCSWVIRVDRNHRVLLNFTDFDLEPQDSCIMAY-- 1567
Query: 411 VRDGYWRKAPLLGRFCG-DKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEATCGGD-M 468
DG L R CG +++ P+VS+ + L++ F+S + +GF A + CGG +
Sbjct: 1568 --DGLSSTMSRLARTCGREQLANPIVSSGNSLFLRFQSGPSRQNRGFRAQFRQACGGHIL 1625
Query: 469 NKDAGQIQSPNYPDDYRPSKECVWRITVSEGF-HVGLTFQAFEIERHDSCAYDYLEVRDG 527
+ SP +P +Y ++ C W I H+ L+F FE+ER +CA D++E+ DG
Sbjct: 1626 TSSFDTVSSPRFPANYPNNQNCSWIIQAQPPLNHITLSFTHFELERSTTCARDFVEILDG 1685
Query: 528 PTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECSWPDHGG 587
E++ L G +CG + P + S S+ L ++FVSD SI+ GF V
Sbjct: 1686 GHEDAPLRGRYCGTDMPHPITSFSSALTLRFVSDSSISAGGFHTTVTASVS--------- 1736
Query: 588 CEHRCVNTLGSYKCACDPGYELAADKKMCEVACGGFITKLNGTITSPGWPKEYPTNKNCV 647
ACGG G SPG+P YP N CV
Sbjct: 1737 -------------------------------ACGGTFYMAEGIFNSPGYPDIYPPNVECV 1765
Query: 648 WQVVAPAQYRISLQFEVFELEGNDVCKYDFVEVRSGLSPDAKLHGRFCGSETPEVITS-Q 706
W +V+ R+ L F F+LE + C DFVE+R G + L GR+CG+ P +S
Sbjct: 1766 WNIVSSPGNRLQLSFISFQLEDSQDCSRDFVEIREG-NATGHLVGRYCGNSFPLNYSSIV 1824
Query: 707 SNNMRVEFKSDNTVSKRGFRAHFFSDKDECAKDNGGCQHECVNTFGSYLCRCRNGYWLHE 766
+ + V F SD + S GF+A F + FG+
Sbjct: 1825 GHTLWVRFISDGSGSGTGFQATF------------------MKIFGN------------- 1853
Query: 767 NGHDCKEAGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQH 826
I G +ASP WP+ YP W ++ A H V E +IE+
Sbjct: 1854 -----------DNIVGTHGKVASPFWPENYPHNSNYQWTVNVNASHVVHGRILEMDIEEI 1902
Query: 827 QECAYDHLEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGF----- 881
Q C YD L +YDGP A ++G +CG+ + + ++G+S+ FYSD+S+ KGF
Sbjct: 1903 QNCYYDKLRIYDGPSIHARLIGAYCGT-QTESFSSTGNSLTFHFYSDSSISGKGFLLEWF 1961
Query: 882 ---------QAVHSTECGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVE 932
+ CGG L+ L+S ++Y + C W+I A D VE
Sbjct: 1962 AVDAPDGVLPTIAPGACGGFLRTGDAPVFLFSPG--WPDSYSNRVDCTWLIQAPDS-TVE 2018
Query: 933 LTFRTFEVEEEADCGYDYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDT 992
L + ++E C YD + DG ++ A +L CG I S G+ + IRF +D +
Sbjct: 2019 LNILSLDIESHRTCAYDSLVIRDGDNNLAQQLAVLCGREIPGPIRSTGEYMFIRFTSDSS 2078
Query: 993 INKKGFHARY 1002
+ + GF+A +
Sbjct: 2079 VTRAGFNASF 2088
Score = 296 bits (758), Expect = 7e-80
Identities = 205/671 (30%), Positives = 292/671 (43%), Gaps = 99/671 (14%)
Query: 340 AQARKLYKCPACGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLF 399
A R +Y+ ACG+ L G +P FPN YP C W I + I+LNFT ++
Sbjct: 807 ASFRAVYQV-ACGDELTGE-GVIRSPFFPNVYPGERTCRWTIHQPQSQVILLNFTVFEIG 864
Query: 400 KSRLCWYDYVEVRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGF--- 456
S C DYVE+ +P ++CG IP + S + L+V F SS+ GF
Sbjct: 865 SSAHCETDYVEIGSSSILGSPENKKYCGTDIPSFITSVYNFLYVTFVKSSSTENHGFMAK 924
Query: 457 FAAYEATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDS 516
F+A + CG + + G IQSP +P+ Y C W I V + L F+ F +E H +
Sbjct: 925 FSAEDLACGEILTESTGTIQSPGHPNVYPHGINCTWHILVQPNHLIHLMFETFHLEFHYN 984
Query: 517 CAYDYLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKE 576
C DYLEV D +E S +G +CG P + SS N L + FV+D + GF N+
Sbjct: 985 CTNDYLEVYDTDSETS--LGRYCGKSIPPSLTSSGNSLMLVFVTDSDLAYEGFLINY--- 1039
Query: 577 VDECSWPDHGGCEHRCVNTLGSYKCACDPGYELAADKKMCEVACGGFITKLNGTITSPGW 636
+ AC T GT TSP +
Sbjct: 1040 -----------------------------------EAISAATACLQDYTDDLGTFTSPNF 1064
Query: 637 PKEYPTNKNCVWQVVAPAQYRISLQFEVFELE---GNDVCKYDFVEVRSGLSPDAKLHGR 693
P YP N C++++ I++ F F LE GN DF+E+R G + L G
Sbjct: 1065 PNNYPNNWECIYRITVRTGQLIAVHFTNFSLEEAIGNYYT--DFLEIRDGGYEKSPLLGI 1122
Query: 694 FCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECAKDNGGCQHECVNTFGS 753
F GS P I S SN + ++FKSD ++ GF A
Sbjct: 1123 FYGSNLPPTIISHSNKLWLKFKSDQIDTRSGFSA-------------------------- 1156
Query: 754 YLCRCRNGYWLHENGHDCKEAGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHR 813
YW D GC +++ GT SPN+P Y EC W + S+ G
Sbjct: 1157 --------YW------DGSSTGCGGNLTTSSGTFISPNYPMPYYHSSECYWWLKSSHGSA 1202
Query: 814 VKLTFNEFEIEQHQECAYDHLEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSD 873
+L F +F +E H C D+L +YDGP S + +L + CG +KP +SG SMF++ +D
Sbjct: 1203 FELEFKDFHLEHHPNCTLDYLAVYDGPSSNSHLLTQLCGDEKPPLIRSSGDSMFIKLRTD 1262
Query: 874 ASVQRKGFQAVHSTECGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVEL 933
Q +GF+A + C + QT + + N Y C+W I A G V
Sbjct: 1263 EGQQGRGFKAEYRQTCENVVIVN-QTYGILESIGY-PNPYSENQHCNWTIRATTGNTVNY 1320
Query: 934 TFRTFEVEEEADCGYDYMEAYDGYDSSAPR-LGRFCGSGPLEEIYSAGDSLMIRFRTDDT 992
TF F++E +C DY+E YDG PR +GR+CG + L + TD
Sbjct: 1321 TFLAFDLEHHINCSTDYLELYDG-----PRQMGRYCGVDLPPPGSTTSSKLQVLLLTDGV 1375
Query: 993 -INKKGFHARY 1002
+KGF ++
Sbjct: 1376 GRREKGFQMQW 1386
Score = 285 bits (730), Expect = 1e-76
Identities = 195/681 (28%), Positives = 312/681 (45%), Gaps = 114/681 (16%)
Query: 353 ETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVEVR 412
+ + T G ++P +P YP S+ W ++V + MD+ + + C+YD + +
Sbjct: 1854 DNIVGTHGKVASPFWPENYPHNSNYQWTVNVNASHVVHGRILEMDIEEIQNCYYDKLRIY 1913
Query: 413 DGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEAT--------- 463
DG A L+G +CG + E ST + L F S S+I GKGF + A
Sbjct: 1914 DGPSIHARLIGAYCGTQT-ESFSSTGNSLTFHFYSDSSISGKGFLLEWFAVDAPDGVLPT 1972
Query: 464 -----CGGDMNKDAGQIQ--SPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDS 516
CGG + + SP +PD Y +C W I + V L + +IE H +
Sbjct: 1973 IAPGACGGFLRTGDAPVFLFSPGWPDSYSNRVDCTWLIQAPDST-VELNILSLDIESHRT 2031
Query: 517 CAYDYLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKE 576
CAYD L +RDG + + CG E P ++S+ ++++F SD S+ +AGF A+F K
Sbjct: 2032 CAYDSLVIRDGDNNLAQQLAVLCGREIPGPIRSTGEYMFIRFTSDSSVTRAGFNASFHK- 2090
Query: 577 VDECSWPDHGGCEHRCVNTLGSYKCACDPGYELAADKKMCEVACGGFITKLNGTITSPGW 636
+CGG++ G ITSP +
Sbjct: 2091 ------------------------------------------SCGGYLHADRGIITSPKY 2108
Query: 637 PKEYPTNKNCVWQVVAPAQYRISLQFEV-FEL-EGNDVCKY-DFVEVRSG-------LSP 686
P+ YP+N NC W V+ + I++ FE F++ G+ C D++ +R+G L P
Sbjct: 2109 PETYPSNLNCSWHVLVQSGLTIAVHFEQPFQIPNGDSSCNQGDYLVLRNGPDICSPPLGP 2168
Query: 687 DAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECAKDNGGCQHE 746
+G FCGS + + N M V+F SD++ +GF+ + + C GG
Sbjct: 2169 PGG-NGHFCGSHASSTLFTSDNQMFVQFISDHSNEGQGFKIKYEAKSLAC----GG---- 2219
Query: 747 CVNTFGSYLCRCRNGYWLHENGHDCKEAGCAHKISSVEGTLASPNWPDKYPSRRECTWNI 806
N Y HD AG + SPN P YP +C W +
Sbjct: 2220 -------------NVYI-----HDADSAGY----------VTSPNHPHNYPPHADCIWIL 2251
Query: 807 SSTAGHRVKLTFNE-FEIEQHQECAYDHLEMYDGPDSLAPILGRFCGSKKPDPTVASGSS 865
++ R++L F + F+IE C ++LE+ DG DS APIL +FCG+ P +SG
Sbjct: 2252 AAPPETRIQLQFEDRFDIEVTPNCTSNYLELRDGVDSDAPILSKFCGTSLPSSQWSSGEV 2311
Query: 866 MFLRFYSDASVQRKGFQAVHS-TECGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIV 924
M+LRF SD S GF+A +S +CGGR+ + E H Y C+W +
Sbjct: 2312 MYLRFRSDNSPTHVGFKAKYSIAQCGGRVPGQSGVVESIGHPTL---PYRDNLFCEWHLQ 2368
Query: 925 AEDGYGVELTFRTFEVEEEADCGYDYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLM 984
G+ + ++F F ++ + C D++E +D + +S LGR+CG+ + I ++ ++ +
Sbjct: 2369 GLSGHYLTISFEDFNLQNSSGCEKDFVEIWDNH-TSGNILGRYCGNTIPDSIDTSSNTAV 2427
Query: 985 IRFRTDDTINKKGFHARYTST 1005
+RF TD ++ GF R+ S+
Sbjct: 2428 VRFVTDGSVTASGFRLRFESS 2448
Score = 283 bits (723), Expect = 8e-76
Identities = 192/682 (28%), Positives = 305/682 (44%), Gaps = 117/682 (17%)
Query: 350 ACGETLQ--DTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYD 407
ACG L+ D +PG+P+ Y + C W I P + LN S+D+ R C YD
Sbjct: 1977 ACGGFLRTGDAPVFLFSPGWPDSYSNRVDCTWLIQA-PDSTVELNILSLDIESHRTCAYD 2035
Query: 408 YVEVRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEATCGGD 467
+ +RDG A L CG +IP P+ ST +++ F S S++ GF A++ +CGG
Sbjct: 2036 SLVIRDGDNNLAQQLAVLCGREIPGPIRSTGEYMFIRFTSDSSVTRAGFNASFHKSCGGY 2095
Query: 468 MNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTF-QAFEIERHDSCAY--DYLEV 524
++ D G I SP YP+ Y + C W + V G + + F Q F+I DS DYL +
Sbjct: 2096 LHADRGIITSPKYPETYPSNLNCSWHVLVQSGLTIAVHFEQPFQIPNGDSSCNQGDYLVL 2155
Query: 525 RDGPTEESALIG------HFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVD 578
R+GP S +G HFCG + +S N+++++F+SD S GF + +
Sbjct: 2156 RNGPDICSPPLGPPGGNGHFCGSHASSTLFTSDNQMFVQFISDHSNEGQGFKIKYEAK-- 2213
Query: 579 ECSWPDHGGCEHRCVNTLGSYKCACDPGYELAADKKMCEVACGGFI----TKLNGTITSP 634
+ACGG + G +TSP
Sbjct: 2214 --------------------------------------SLACGGNVYIHDADSAGYVTSP 2235
Query: 635 GWPKEYPTNKNCVWQVVAPAQYRISLQFEV-FELEGNDVCKYDFVEVRSGLSPDAKLHGR 693
P YP + +C+W + AP + RI LQFE F++E C +++E+R G+ DA + +
Sbjct: 2236 NHPHNYPPHADCIWILAAPPETRIQLQFEDRFDIEVTPNCTSNYLELRDGVDSDAPILSK 2295
Query: 694 FCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECAKDNGGCQHECVNTFGS 753
FCG+ P S M + F+SDN+ + GF+A +
Sbjct: 2296 FCGTSLPSSQWSSGEVMYLRFRSDNSPTHVGFKAKY------------------------ 2331
Query: 754 YLCRCRNGYWLHENGHDCKEAGCAHKISSVEGTLASPNWPD-KYPSRRECTWNISSTAGH 812
A C ++ G + S P Y C W++ +GH
Sbjct: 2332 ------------------SIAQCGGRVPGQSGVVESIGHPTLPYRDNLFCEWHLQGLSGH 2373
Query: 813 RVKLTFNEFEIEQHQECAYDHLEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYS 872
+ ++F +F ++ C D +E++D S ILGR+CG+ PD S ++ +RF +
Sbjct: 2374 YLTISFEDFNLQNSSGCEKDFVEIWDNHTS-GNILGRYCGNTIPDSIDTSSNTAVVRFVT 2432
Query: 873 DASVQRKGFQAVHST---ECGGRLKAEVQTKELYSHAQFGDNNYPSEAR----CDWVIVA 925
D SV GF+ + ECGG L+ + T F NYP+ C+W I A
Sbjct: 2433 DGSVTASGFRLRFESSMEECGGDLQGSIGT--------FTSPNYPNPNPHGRICEWRITA 2484
Query: 926 EDGYGVELTFRTFEVEEEADCGYDYMEAYDGYDSSAPRLGRFCGSGPLE-EIYSAGDSLM 984
+G + L F + C +++ ++G S++P+L + C S + EI S+G+++
Sbjct: 2485 PEGRRITLMFNNLRLATHPSCNNEHVIVFNGIRSNSPQLEKLCSSVNVSNEIKSSGNTMK 2544
Query: 985 IRFRTDDTINKKGFHARYTSTK 1006
+ F TD + GF A YTS++
Sbjct: 2545 VIFFTDGSRPYGGFTASYTSSE 2566
Score = 275 bits (703), Expect = 2e-73
Identities = 195/721 (27%), Positives = 301/721 (41%), Gaps = 108/721 (14%)
Query: 291 ETYDFDSIMHYARNTFSRGVFLDTILPRQ---DDNGVRPTIGQRVRLSQGDIAQARKLYK 347
+ YD DS + F G F + LP + DN + + L G R +
Sbjct: 533 QVYDGDS-----SSAFQLGRFCGSSLPHELLSSDNALYFHLYSE-HLRNGRGFTVRWETQ 586
Query: 348 CPACGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYD 407
P CG L G+ +PG+P YP CVW + +P + F ++ L C D
Sbjct: 587 QPECGGILTGPYGSIKSPGYPGNYPPGRDCVWIVVTSPDLLVTFTFGTLSLEHHDDCNKD 646
Query: 408 YVEVRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAY-----EA 462
Y+E+RDG + PLLG+FC PL +T + F S S I +GF Y +
Sbjct: 647 YLEIRDGPLYQDPLLGKFCTTFSVPPLQTTGPFARIHFHSDSQISDQGFHITYLTSPSDL 706
Query: 463 TCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDYL 522
CGG+ G++ P + +++CV+ + +G + + F E++ + +Y+
Sbjct: 707 RCGGNYTDPEGELFLPELSGPFTHTRQCVYMMKQPQGEQIQINFTHVELQCQSDSSQNYI 766
Query: 523 EVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECSW 582
EVRDG T L+G CG +KS +N +W++F D S+ KA F A +
Sbjct: 767 EVRDGET----LLGKVCGNGTISHIKSITNSVWIRFKIDASVEKASFRAVY--------- 813
Query: 583 PDHGGCEHRCVNTLGSYKCACDPGYELAADKKMCEVACGGFITKLNGTITSPGWPKEYPT 642
+VACG +T G I SP +P YP
Sbjct: 814 ----------------------------------QVACGDELTG-EGVIRSPFFPNVYPG 838
Query: 643 NKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVEVRSGLSPDAKLHGRFCGSETPEV 702
+ C W + P I L F VFE+ + C+ D+VE+ S + + ++CG++ P
Sbjct: 839 ERTCRWTIHQPQSQVILLNFTVFEIGSSAHCETDYVEIGSSSILGSPENKKYCGTDIPSF 898
Query: 703 ITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECAKDNGGCQHECVNTFGSYLCRCRNGY 762
ITS N + V F ++ GF A F
Sbjct: 899 ITSVYNFLYVTFVKSSSTENHGFMAKF--------------------------------- 925
Query: 763 WLHENGHDCKEAGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFE 822
++ C ++ GT+ SP P+ YP CTW+I H + L F F
Sbjct: 926 -------SAEDLACGEILTESTGTIQSPGHPNVYPHGINCTWHILVQPNHLIHLMFETFH 978
Query: 823 IEQHQECAYDHLEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQ 882
+E H C D+LE+YD + LGR+CG P +SG+S+ L F +D+ + +GF
Sbjct: 979 LEFHYNCTNDYLEVYDTDSETS--LGRYCGKSIPPSLTSSGNSLMLVFVTDSDLAYEGFL 1036
Query: 883 AVHSTECGGRLKAEVQTKEL--YSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEV 940
+ + T +L ++ F NNYP+ C + I G + + F F +
Sbjct: 1037 INYEAISAATACLQDYTDDLGTFTSPNF-PNNYPNNWECIYRITVRTGQLIAVHFTNFSL 1095
Query: 941 EEEADCGY-DYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFH 999
EE Y D++E DG +P LG F GS I S + L ++F++D + GF
Sbjct: 1096 EEAIGNYYTDFLEIRDGGYEKSPLLGIFYGSNLPPTIISHSNKLWLKFKSDQIDTRSGFS 1155
Query: 1000 A 1000
A
Sbjct: 1156 A 1156
Score = 274 bits (701), Expect = 3e-73
Identities = 187/663 (28%), Positives = 281/663 (42%), Gaps = 101/663 (15%)
Query: 351 CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVE 410
CG D G P + CV+ + GE+I +NFT ++L +Y+E
Sbjct: 708 CGGNYTDPEGELFLPELSGPFTHTRQCVYMMKQPQGEQIQINFTHVELQCQSDSSQNYIE 767
Query: 411 VRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEATCGGDMNK 470
VRDG LLG+ CG+ + S + +W+ F+ +++ F A Y+ CG ++
Sbjct: 768 VRDG----ETLLGKVCGNGTISHIKSITNSVWIRFKIDASVEKASFRAVYQVACGDELTG 823
Query: 471 DAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDYLEVRDGPTE 530
+ G I+SP +P+ Y + C W I + + L F FEI C DY+E+
Sbjct: 824 E-GVIRSPFFPNVYPGERTCRWTIHQPQSQVILLNFTVFEIGSSAHCETDYVEIGSSSIL 882
Query: 531 ESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECSWPDHGGCEH 590
S +CG + P + S N L++ FV S GF A F E
Sbjct: 883 GSPENKKYCGTDIPSFITSVYNFLYVTFVKSSSTENHGFMAKFSAE-------------- 928
Query: 591 RCVNTLGSYKCACDPGYELAADKKMCEVACGGFITKLNGTITSPGWPKEYPTNKNCVWQV 650
++ACG +T+ GTI SPG P YP NC W +
Sbjct: 929 --------------------------DLACGEILTESTGTIQSPGHPNVYPHGINCTWHI 962
Query: 651 VAPAQYRISLQFEVFELEGNDVCKYDFVEVRSGLSPDAKLHGRFCGSETPEVITSQSNNM 710
+ + I L FE F LE + C D++EV S + GR+CG P +TS N++
Sbjct: 963 LVQPNHLIHLMFETFHLEFHYNCTNDYLEVYDTDSETSL--GRYCGKSIPPSLTSSGNSL 1020
Query: 711 RVEFKSDNTVSKRGFRAHFFSDKDECAKDNGGCQHECVNTFGSYLCRCRNGYWLHENGHD 770
+ F +D+ ++ GF ++ E ++
Sbjct: 1021 MLVFVTDSDLAYEGFLINY----------------EAISA-------------------- 1044
Query: 771 CKEAGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECA 830
C + GT SPN+P+ YP+ EC + I+ G + + F F +E+
Sbjct: 1045 --ATACLQDYTDDLGTFTSPNFPNNYPNNWECIYRITVRTGQLIAVHFTNFSLEEAIGNY 1102
Query: 831 Y-DHLEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQAV---HS 886
Y D LE+ DG +P+LG F GS P ++ + ++L+F SD R GF A S
Sbjct: 1103 YTDFLEIRDGGYEKSPLLGIFYGSNLPPTIISHSNKLWLKFKSDQIDTRSGFSAYWDGSS 1162
Query: 887 TECGGRLKAEVQTKELYSHAQFGDNNYPS----EARCDWVIVAEDGYGVELTFRTFEVEE 942
T CGG L S F NYP + C W + + G EL F+ F +E
Sbjct: 1163 TGCGGNLTT--------SSGTFISPNYPMPYYHSSECYWWLKSSHGSAFELEFKDFHLEH 1214
Query: 943 EADCGYDYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARY 1002
+C DY+ YDG S++ L + CG I S+GDS+ I+ RTD+ +GF A Y
Sbjct: 1215 HPNCTLDYLAVYDGPSSNSHLLTQLCGDEKPPLIRSSGDSMFIKLRTDEGQQGRGFKAEY 1274
Query: 1003 TST 1005
T
Sbjct: 1275 RQT 1277
Score = 269 bits (688), Expect = 9e-72
Identities = 196/674 (29%), Positives = 295/674 (43%), Gaps = 112/674 (16%)
Query: 351 CGETLQDTT-GNFSAPGFPNGYPSYS---HCVWRISVTPGE---KIVLNFTSMDLFKSRL 403
CG +L +T GNF++PG+ +G +YS +C W +S P + I ++F L +
Sbjct: 2570 CGGSLPNTPEGNFTSPGY-DGVRNYSRNLNCEWTLS-NPNQGNSSISIHFEDFYLESHQD 2627
Query: 404 CWYDYVEVRDGYWRKAPLLGRFCGDKIPE-PLVSTDSRLWVEFRSSSNILGKGFFAAYEA 462
C +D +E R G PL+ R CG P PLV S++W+ F ++ + GF A Y
Sbjct: 2628 CQFDVLEFRVGD-ADGPLMWRLCGPSKPTLPLVIPYSQVWIHFVTNERVEHIGFHAKYSF 2686
Query: 463 T-CGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDY 521
T CGG D+G I SPNYP+ Y C + +G + LTF F+IE H +CA+D
Sbjct: 2687 TDCGGIQIGDSGVITSPNYPNAYDSLTHCSSLLEAPQGHTITLTFSDFDIEPHTTCAWDS 2746
Query: 522 LEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECS 581
+ VR+G + ES +IG +CG P ++S SN+L + F SD S+ GF A +
Sbjct: 2747 VTVRNGGSPESPIIGQYCGNSNPRTIQSGSNQLVVTFNSDHSLQGGGFYA---------T 2797
Query: 582 WPDHGGCEHRCVNTLGSYKCACDPGYELAADKKMCEVACGGFITKLNGTITSPGWPKEYP 641
W TLG CGG NGTI SP WP+ +P
Sbjct: 2798 WN---------TQTLG----------------------CGGIFHSDNGTIRSPHWPQNFP 2826
Query: 642 TNKNCVWQVVAPAQYRISLQFEVFEL--EGNDVCKYDFVEVRSGLSP-DAKLHGRFCGSE 698
N C W + + + F+ L G+ C+ FV+V +G D L CG+
Sbjct: 2827 ENSRCSWTAITHKSKHLEISFDNNFLIPSGDGQCQNSFVKVWAGTEEVDKALLATGCGNV 2886
Query: 699 TPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECAKDNGGCQHECVNTFGSYLCRC 758
P + + SN F+S + +GF A F S
Sbjct: 2887 APGPVITPSNTFTAVFQSQEAPA-QGFSASFVS--------------------------- 2918
Query: 759 RNGYWLHENGHDCKEAGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTF 818
C + G + SPN+P +Y + CT+ I + V LTF
Sbjct: 2919 ----------------RCGSNFTGPSGYIISPNYPKQYDNNMNCTYVIEANPLSVVLLTF 2962
Query: 819 NEFEIEQHQ----ECAYDHLEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDA 874
F +E C D + + G ++ CG + P P +G + L FYS+
Sbjct: 2963 VSFHLEARSAVTGSCVNDGVHIIRGYSVMSTPFATVCGDEMPAPLTIAG-PVLLNFYSNE 3021
Query: 875 SVQRKGFQ-AVHSTECGG--RLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGV 931
+ GF+ + CGG + + T YS+A +YP++ C + I D +
Sbjct: 3022 QITDFGFKFSYRIISCGGVFNFSSGIITSPAYSYA-----DYPNDMHCLYTITVSDDKVI 3076
Query: 932 ELTFRTFEVEEEADCGYDYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDD 991
EL F F+V C +DY+ YDG ++S P LG+FCGS + S+ +S+++ F+TD
Sbjct: 3077 ELKFSDFDVVPSTSCSHDYLAIYDGANTSDPLLGKFCGSKRPPNVKSSNNSMLLVFKTDS 3136
Query: 992 TINKKGFHARYTST 1005
KG+ + T
Sbjct: 3137 FQTAKGWKMSFRQT 3150
Score = 265 bits (677), Expect = 2e-70
Identities = 177/672 (26%), Positives = 299/672 (44%), Gaps = 98/672 (14%)
Query: 347 KCPACGETLQ----DTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTS-MDLFKS 401
K ACG + D+ G ++P P+ YP ++ C+W ++ P +I L F D+ +
Sbjct: 2213 KSLACGGNVYIHDADSAGYVTSPNHPHNYPPHADCIWILAAPPETRIQLQFEDRFDIEVT 2272
Query: 402 RLCWYDYVEVRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYE 461
C +Y+E+RDG AP+L +FCG +P S+ +++ FRS ++ GF A Y
Sbjct: 2273 PNCTSNYLELRDGVDSDAPILSKFCGTSLPSSQWSSGEVMYLRFRSDNSPTHVGFKAKYS 2332
Query: 462 -ATCGGDMNKDAGQIQSPNYPD-DYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAY 519
A CGG + +G ++S +P YR + C W + G ++ ++F+ F ++ C
Sbjct: 2333 IAQCGGRVPGQSGVVESIGHPTLPYRDNLFCEWHLQGLSGHYLTISFEDFNLQNSSGCEK 2392
Query: 520 DYLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDE 579
D++E+ D T + ++G +CG P+ + +SSN ++FV+DGS+ +GF F ++E
Sbjct: 2393 DFVEIWDNHTSGN-ILGRYCGNTIPDSIDTSSNTAVVRFVTDGSVTASGFRLRFESSMEE 2451
Query: 580 CSWPDHGGCEHRCVNTLGSYKCACDPGYELAADKKMCEVACGGFITKLNGTITSPGWPKE 639
CGG + GT TSP +P
Sbjct: 2452 ----------------------------------------CGGDLQGSIGTFTSPNYPNP 2471
Query: 640 YPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVEVRSGLSPDAKLHGRFCGS-E 698
P + C W++ AP RI+L F L + C + V V +G+ ++ + C S
Sbjct: 2472 NPHGRICEWRITAPEGRRITLMFNNLRLATHPSCNNEHVIVFNGIRSNSPQLEKLCSSVN 2531
Query: 699 TPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECAKDNGGCQHECVNTFGSYLCRC 758
I S N M+V F +D + GF A + S +D C NT
Sbjct: 2532 VSNEIKSSGNTMKVIFFTDGSRPYGGFTASYTSSEDAV------CGGSLPNT-------- 2577
Query: 759 RNGYWLHENGHDCKEAGCAHKISSVEGTLASPNWPD--KYPSRRECTWNIS--STAGHRV 814
EG SP + Y C W +S + +
Sbjct: 2578 ------------------------PEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSI 2613
Query: 815 KLTFNEFEIEQHQECAYDHLEMYDGPDSLAPILGRFCGSKKPD-PTVASGSSMFLRFYSD 873
+ F +F +E HQ+C +D LE G D+ P++ R CG KP P V S +++ F ++
Sbjct: 2614 SIHFEDFYLESHQDCQFDVLEFRVG-DADGPLMWRLCGPSKPTLPLVIPYSQVWIHFVTN 2672
Query: 874 ASVQRKGFQAVHS-TECGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVE 932
V+ GF A +S T+CGG ++ + + + N Y S C ++ A G+ +
Sbjct: 2673 ERVEHIGFHAKYSFTDCGG---IQIGDSGVITSPNY-PNAYDSLTHCSSLLEAPQGHTIT 2728
Query: 933 LTFRTFEVEEEADCGYDYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDT 992
LTF F++E C +D + +G +P +G++CG+ I S + L++ F +D +
Sbjct: 2729 LTFSDFDIEPHTTCAWDSVTVRNGGSPESPIIGQYCGNSNPRTIQSGSNQLVVTFNSDHS 2788
Query: 993 INKKGFHARYTS 1004
+ GF+A + +
Sbjct: 2789 LQGGGFYATWNT 2800
Score = 263 bits (673), Expect = 5e-70
Identities = 180/658 (27%), Positives = 273/658 (41%), Gaps = 98/658 (14%)
Query: 351 CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVE 410
CGE+L G+FS GY +C W I G+ + + FT L C +++++
Sbjct: 474 CGESLSGINGSFSYRSPDVGYVHDVNCFWVIKTEMGKVLRITFTFFRLESMDNCPHEFLQ 533
Query: 411 VRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEAT---CGGD 467
V DG A LGRFCG +P L+S+D+ L+ S G+GF +E CGG
Sbjct: 534 VYDGDSSSAFQLGRFCGSSLPHELLSSDNALYFHLYSEHLRNGRGFTVRWETQQPECGGI 593
Query: 468 MNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDYLEVRDG 527
+ G I+SP YP +Y P ++CVW + S V TF +E HD C DYLE+RDG
Sbjct: 594 LTGPYGSIKSPGYPGNYPPGRDCVWIVVTSPDLLVTFTFGTLSLEHHDDCNKDYLEIRDG 653
Query: 528 PTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECSWPDHGG 587
P + L+G FC ++++ + F SD I+ GF +
Sbjct: 654 PLYQDPLLGKFCTTFSVPPLQTTGPFARIHFHSDSQISDQGFHITYLTSPS--------- 704
Query: 588 CEHRCVNTLGSYKCACDPGYELAADKKMCEVACGGFITKLNGTITSPGWPKEYPTNKNCV 647
++ CGG T G + P + + CV
Sbjct: 705 -----------------------------DLRCGGNYTDPEGELFLPELSGPFTHTRQCV 735
Query: 648 WQVVAPAQYRISLQFEVFELEGNDVCKYDFVEVRSGLSPDAKLHGRFCGSETPEVITSQS 707
+ + P +I + F EL+ +++EVR G L G+ CG+ T I S +
Sbjct: 736 YMMKQPQGEQIQINFTHVELQCQSDSSQNYIEVRDG----ETLLGKVCGNGTISHIKSIT 791
Query: 708 NNMRVEFKSDNTVSKRGFRAHFFSDKDECAKDNGGCQHECVNTFGSYLCRCRNGYWLHEN 767
N++ + FK D +V K FRA +
Sbjct: 792 NSVWIRFKIDASVEKASFRAVY-------------------------------------- 813
Query: 768 GHDCKEAGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQ 827
+ C +++ EG + SP +P+ YP R C W I + L F FEI
Sbjct: 814 -----QVACGDELTG-EGVIRSPFFPNVYPGERTCRWTIHQPQSQVILLNFTVFEIGSSA 867
Query: 828 ECAYDHLEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQAVHST 887
C D++E+ +P ++CG+ P + + +++ F +S + GF A S
Sbjct: 868 HCETDYVEIGSSSILGSPENKKYCGTDIPSFITSVYNFLYVTFVKSSSTENHGFMAKFSA 927
Query: 888 E---CGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEA 944
E CG L T + H N YP C W I+ + + + L F TF +E
Sbjct: 928 EDLACGEILTESTGTIQSPGH----PNVYPHGINCTWHILVQPNHLIHLMFETFHLEFHY 983
Query: 945 DCGYDYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARY 1002
+C DY+E YD S LGR+CG + S+G+SLM+ F TD + +GF Y
Sbjct: 984 NCTNDYLEVYD--TDSETSLGRYCGKSIPPSLTSSGNSLMLVFVTDSDLAYEGFLINY 1039
Score = 257 bits (656), Expect = 4e-68
Identities = 185/682 (27%), Positives = 293/682 (42%), Gaps = 111/682 (16%)
Query: 350 ACGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTS---MDLFKSRLCWY 406
+CG L G ++P +P YPS +C W + V G I ++F + S
Sbjct: 2091 SCGGYLHADRGIITSPKYPETYPSNLNCSWHVLVQSGLTIAVHFEQPFQIPNGDSSCNQG 2150
Query: 407 DYVEVRDGYWRKAPLLG------RFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAY 460
DY+ +R+G +P LG FCG L ++D++++V+F S + G+GF Y
Sbjct: 2151 DYLVLRNGPDICSPPLGPPGGNGHFCGSHASSTLFTSDNQMFVQFISDHSNEGQGFKIKY 2210
Query: 461 EA---TCGGDMN----KDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQ-AFEIE 512
EA CGG++ AG + SPN+P +Y P +C+W + + L F+ F+IE
Sbjct: 2211 EAKSLACGGNVYIHDADSAGYVTSPNHPHNYPPHADCIWILAAPPETRIQLQFEDRFDIE 2270
Query: 513 RHDSCAYDYLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAAN 572
+C +YLE+RDG ++ ++ FCG P SS ++++F SD S GF A
Sbjct: 2271 VTPNCTSNYLELRDGVDSDAPILSKFCGTSLPSSQWSSGEVMYLRFRSDNSPTHVGFKAK 2330
Query: 573 FFKEVDECSWPDHGGCEHRCVNTLGSYKCACDPGYELAADKKMCEVACGGFITKLNGTIT 632
Y +A CGG + +G +
Sbjct: 2331 ----------------------------------YSIA--------QCGGRVPGQSGVVE 2348
Query: 633 SPGWPK-EYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVEVRSGLSPDAKLH 691
S G P Y N C W + + + +++ FE F L+ + C+ DFVE+ +
Sbjct: 2349 SIGHPTLPYRDNLFCEWHLQGLSGHYLTISFEDFNLQNSSGCEKDFVEIWDN-HTSGNIL 2407
Query: 692 GRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECAKDNGGCQHECVNTF 751
GR+CG+ P+ I + SN V F +D +V+ GFR F S +EC D
Sbjct: 2408 GRYCGNTIPDSIDTSSNTAVVRFVTDGSVTASGFRLRFESSMEECGGD------------ 2455
Query: 752 GSYLCRCRNGYWLHENGHDCKEAGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAG 811
+ GT SPN+P+ P R C W I++ G
Sbjct: 2456 ----------------------------LQGSIGTFTSPNYPNPNPHGRICEWRITAPEG 2487
Query: 812 HRVKLTFNEFEIEQHQECAYDHLEMYDGPDSLAPILGRFCGSKKPDPTV-ASGSSMFLRF 870
R+ L FN + H C +H+ +++G S +P L + C S + +SG++M + F
Sbjct: 2488 RRITLMFNNLRLATHPSCNNEHVIVFNGIRSNSPQLEKLCSSVNVSNEIKSSGNTMKVIF 2547
Query: 871 YSDASVQRKGFQAVHSTE----CGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVI--V 924
++D S GF A +++ CGG L S G NY C+W +
Sbjct: 2548 FTDGSRPYGGFTASYTSSEDAVCGGSL-PNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNP 2606
Query: 925 AEDGYGVELTFRTFEVEEEADCGYDYMEAYDGYDSSAPRLGRFCG-SGPLEEIYSAGDSL 983
+ + + F F +E DC +D +E G D+ P + R CG S P + +
Sbjct: 2607 NQGNSSISIHFEDFYLESHQDCQFDVLEFRVG-DADGPLMWRLCGPSKPTLPLVIPYSQV 2665
Query: 984 MIRFRTDDTINKKGFHARYTST 1005
I F T++ + GFHA+Y+ T
Sbjct: 2666 WIHFVTNERVEHIGFHAKYSFT 2687
Score = 242 bits (618), Expect = 1e-63
Identities = 182/676 (26%), Positives = 282/676 (41%), Gaps = 109/676 (16%)
Query: 351 CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRL----CWY 406
CG +G +P +P Y + +C + I P ++L F S L C
Sbjct: 2920 CGSNFTGPSGYIISPNYPKQYDNNMNCTYVIEANPLSVVLLTFVSFHLEARSAVTGSCVN 2979
Query: 407 DYVEVRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEA-TCG 465
D V + GY + CGD++P PL L + F S+ I GF +Y +CG
Sbjct: 2980 DGVHIIRGYSVMSTPFATVCGDEMPAPLTIAGPVL-LNFYSNEQITDFGFKFSYRIISCG 3038
Query: 466 GDMNKDAGQIQSPNYP-DDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDYLEV 524
G N +G I SP Y DY C++ ITVS+ + L F F++ SC++DYL +
Sbjct: 3039 GVFNFSSGIITSPAYSYADYPNDMHCLYTITVSDDKVIELKFSDFDVVPSTSCSHDYLAI 3098
Query: 525 RDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECSWPD 584
DG L+G FCG ++P +VKSS+N + + F +D G+ +F +
Sbjct: 3099 YDGANTSDPLLGKFCGSKRPPNVKSSNNSMLLVFKTDSFQTAKGWKMSFRQ--------- 3149
Query: 585 HGGCEHRCVNTLGSYKCACDPGYELAADKKMCEVACGGFITKLNGTITSPGWPKE--YPT 642
TLG + CGG++T N T SP Y
Sbjct: 3150 ----------TLGPQQ------------------GCGGYLTGSNNTFASPDSDSNGMYDK 3181
Query: 643 NKNCVWQVVAPAQYRISLQFEVFELEGNDV---CKYDFVEVRSGLSPDAKLHGRFCGSET 699
N NCVW ++AP I L F F LE C YD+V++ G S +A L G FCGS
Sbjct: 3182 NLNCVWIIIAPVNKVIHLTFNTFALEAASTRQRCLYDYVKLYDGDSENANLAGTFCGSTV 3241
Query: 700 PEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECAKDNGGCQHECVNTFGSYLCRCR 759
P S N + V+F SD T+ + GF A + C G+Y
Sbjct: 3242 PAPFISSGNFLTVQFISDLTLEREGFNATYTIMDMPCG--------------GTY----- 3282
Query: 760 NGYWLHENGHDCKEAGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFN 819
N W +N ++SPN D CTW I S +VK+T
Sbjct: 3283 NATWTPQN-------------------ISSPNSSDPDVPFSICTWVIDSPPHQQVKITVW 3323
Query: 820 EFEIEQHQECAYDHLEMYDGPDSLAPILGRFCG-SKKPDPTVASGSSMFLRFYSDASVQR 878
++ Q+C ++L++ D P +FCG + P S S + + V R
Sbjct: 3324 ALQLTS-QDCTQNYLQLQDSPQGHGNSRFQFCGRNASAVPVFYSSMSTAMVIFKSGVVNR 3382
Query: 879 KGFQAVHSTECGGRLKAEVQTKELYS--HAQFGD-------NNYPSEARCDWVIVAEDGY 929
R+ Q + H FG+ +NY ++ C + A +
Sbjct: 3383 NS-----------RMSFTYQIADCNRDYHKAFGNLRSPGWPDNYDNDKDCTVTLTAPQNH 3431
Query: 930 GVELTFRTFEVEEEADCGYDYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRT 989
+ L F + +E +C D++E +G +S++P LG++CG+ ++S + L +RF++
Sbjct: 3432 TISLFFHSLGIENSVECRNDFLEVRNGSNSNSPLLGKYCGTLLPNPVFSQNNELYLRFKS 3491
Query: 990 DDTINKKGFHARYTST 1005
D + +G+ +TS+
Sbjct: 3492 DSVTSDRGYEIIWTSS 3507
Score = 241 bits (616), Expect = 2e-63
Identities = 172/680 (25%), Positives = 294/680 (43%), Gaps = 109/680 (16%)
Query: 346 YKCPACGETLQDTTGNFSAPGFPNG-YPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLC 404
Y+ +CG ++G ++P + YP+ HC++ I+V+ + I L F+ D+ S C
Sbjct: 3032 YRIISCGGVFNFSSGIITSPAYSYADYPNDMHCLYTITVSDDKVIELKFSDFDVVPSTSC 3091
Query: 405 WYDYVEVRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEAT- 463
+DY+ + DG PLLG+FCG K P + S+++ + + F++ S KG+ ++ T
Sbjct: 3092 SHDYLAIYDGANTSDPLLGKFCGSKRPPNVKSSNNSMLLVFKTDSFQTAKGWKMSFRQTL 3151
Query: 464 -----CGGDMNKDAGQIQSPNYPDD--YRPSKECVWRITVSEGFHVGLTFQAFEIERHDS 516
CGG + SP+ + Y + CVW I + LTF F +E +
Sbjct: 3152 GPQQGCGGYLTGSNNTFASPDSDSNGMYDKNLNCVWIIIAPVNKVIHLTFNTFALEAAST 3211
Query: 517 ---CAYDYLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANF 573
C YDY+++ DG +E + L G FCG P SS N L ++F+SD ++ + GF A +
Sbjct: 3212 RQRCLYDYVKLYDGDSENANLAGTFCGSTVPAPFISSGNFLTVQFISDLTLEREGFNATY 3271
Query: 574 FKEVDECSWPDHGGCEHRCVNTLGSYKCACDPGYELAADKKMCEVACGGFI--TKLNGTI 631
+ ++ CGG T I
Sbjct: 3272 ----------------------------------------TIMDMPCGGTYNATWTPQNI 3291
Query: 632 TSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVEVRSGLSPDAKLH 691
+SP C W + +P ++ + +L D C ++++++
Sbjct: 3292 SSPNSSDPDVPFSICTWVIDSPPHQQVKITVWALQLTSQD-CTQNYLQLQDSPQGHGNSR 3350
Query: 692 GRFCG---SETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECAKDNGGCQHECV 748
+FCG S P +S S M V FKS V R R F +C +D
Sbjct: 3351 FQFCGRNASAVPVFYSSMSTAM-VIFKSG--VVNRNSRMSFTYQIADCNRDY-------- 3399
Query: 749 NTFGSYLCRCRNGYWLHENGHDCKEAGCAHKISSVEGTLASPNWPDKYPSRRECTWNISS 808
HK G L SP WPD Y + ++CT +++
Sbjct: 3400 -----------------------------HKAF---GNLRSPGWPDNYDNDKDCTVTLTA 3427
Query: 809 TAGHRVKLTFNEFEIEQHQECAYDHLEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFL 868
H + L F+ IE EC D LE+ +G +S +P+LG++CG+ P+P + + ++L
Sbjct: 3428 PQNHTISLFFHSLGIENSVECRNDFLEVRNGSNSNSPLLGKYCGTLLPNPVFSQNNELYL 3487
Query: 869 RFYSDASVQRKGFQAVHSTE---CGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVA 925
RF SD+ +G++ + ++ CGG L + + ++ + YP+ C+WV+VA
Sbjct: 3488 RFKSDSVTSDRGYEIIWTSSPSGCGGTLYGD---RGSFTSPGY-PGTYPNNTYCEWVLVA 3543
Query: 926 EDGYGVELTFRTFEVEEEADCGYDYMEAYDGYDSSAPRLGRFCGSG-PLEEIYSAGDSLM 984
G V + F +++ DC +Y+ YDG ++S+P G +CG + ++ + +
Sbjct: 3544 PAGRLVTINFYFISIDDPGDCVQNYLTLYDGPNASSPSSGPYCGGDTSIAPFVASSNQVF 3603
Query: 985 IRFRTDDTINKKGFHARYTS 1004
I+F D F + S
Sbjct: 3604 IKFHADYARRPSAFRLTWDS 3623
Score = 223 bits (569), Expect = 5e-58
Identities = 168/676 (24%), Positives = 279/676 (41%), Gaps = 105/676 (15%)
Query: 346 YKCPACGETLQDTTGNFSAPGFPN-GYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLC 404
Y CG + +G + G P Y C W + G + ++F +L S C
Sbjct: 2331 YSIAQCGGRVPGQSGVVESIGHPTLPYRDNLFCEWHLQGLSGHYLTISFEDFNLQNSSGC 2390
Query: 405 WYDYVEVRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEAT- 463
D+VE+ D + +LGR+CG+ IP+ + ++ + V F + ++ GF +E++
Sbjct: 2391 EKDFVEIWDNH-TSGNILGRYCGNTIPDSIDTSSNTAVVRFVTDGSVTASGFRLRFESSM 2449
Query: 464 --CGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDY 521
CGGD+ G SPNYP+ + C WRIT EG + L F + H SC ++
Sbjct: 2450 EECGGDLQGSIGTFTSPNYPNPNPHGRICEWRITAPEGRRITLMFNNLRLATHPSCNNEH 2509
Query: 522 LEVRDGPTEESALIGHFC-GYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDEC 580
+ V +G S + C ++KSS N + + F +DGS GF A++ D
Sbjct: 2510 VIVFNGIRSNSPQLEKLCSSVNVSNEIKSSGNTMKVIFFTDGSRPYGGFTASYTSSED-- 2567
Query: 581 SWPDHGGCEHRCVNTLGSYKCACDPGYELAADKKMCEVACGGFITKL-NGTITSPGWP-- 637
CGG + G TSPG+
Sbjct: 2568 -------------------------------------AVCGGSLPNTPEGNFTSPGYDGV 2590
Query: 638 KEYPTNKNCVWQVVAPAQ--YRISLQFEVFELEGNDVCKYDFVEVRSGLSPDAKLHGRFC 695
+ Y N NC W + P Q IS+ FE F LE + C++D +E R G D L R C
Sbjct: 2591 RNYSRNLNCEWTLSNPNQGNSSISIHFEDFYLESHQDCQFDVLEFRVG-DADGPLMWRLC 2649
Query: 696 GSETPEV-ITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECAKDNGGCQHECVNTFGSY 754
G P + + + + + F ++ V GF A + D GG Q
Sbjct: 2650 GPSKPTLPLVIPYSQVWIHFVTNERVEHIGFHAKY------SFTDCGGIQ---------- 2693
Query: 755 LCRCRNGYWLHENGHDCKEAGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRV 814
G + SPN+P+ Y S C+ + + GH +
Sbjct: 2694 --------------------------IGDSGVITSPNYPNAYDSLTHCSSLLEAPQGHTI 2727
Query: 815 KLTFNEFEIEQHQECAYDHLEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDA 874
LTF++F+IE H CA+D + + +G +PI+G++CG+ P + + + + F SD
Sbjct: 2728 TLTFSDFDIEPHTTCAWDSVTVRNGGSPESPIIGQYCGNSNPRTIQSGSNQLVVTFNSDH 2787
Query: 875 SVQRKGFQAVHSTE---CGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGV 931
S+Q GF A +T+ CGG ++ T + N+P +RC W + +
Sbjct: 2788 SLQGGGFYATWNTQTLGCGGIFHSDNGT----IRSPHWPQNFPENSRCSWTAITHKSKHL 2843
Query: 932 ELTF-RTFEVEE-EADCGYDYMEAYDGYDS-SAPRLGRFCGSGPLEEIYSAGDSLMIRFR 988
E++F F + + C +++ + G + L CG+ + + ++ F+
Sbjct: 2844 EISFDNNFLIPSGDGQCQNSFVKVWAGTEEVDKALLATGCGNVAPGPVITPSNTFTAVFQ 2903
Query: 989 TDDTINKKGFHARYTS 1004
+ + +GF A + S
Sbjct: 2904 SQEA-PAQGFSASFVS 2918
Score = 204 bits (519), Expect = 3e-52
Identities = 165/657 (25%), Positives = 272/657 (41%), Gaps = 102/657 (15%)
Query: 351 CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSR--LCWYDY 408
CG G +P +P +P S C W + + ++F + L S C +
Sbjct: 2805 CGGIFHSDNGTIRSPHWPQNFPENSRCSWTAITHKSKHLEISFDNNFLIPSGDGQCQNSF 2864
Query: 409 VEVRDGYWR-KAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEATCGGD 467
V+V G LL CG+ P P+++ + F+S +GF A++ + CG +
Sbjct: 2865 VKVWAGTEEVDKALLATGCGNVAPGPVITPSNTFTAVFQSQE-APAQGFSASFVSRCGSN 2923
Query: 468 MNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHD----SCAYDYLE 523
+G I SPNYP Y + C + I + V LTF +F +E SC D +
Sbjct: 2924 FTGPSGYIISPNYPKQYDNNMNCTYVIEANPLSVVLLTFVSFHLEARSAVTGSCVNDGVH 2983
Query: 524 VRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECSWP 583
+ G + S CG E P + + L + F S+ I GF
Sbjct: 2984 IIRGYSVMSTPFATVCGDEMPAPLTIAGPVL-LNFYSNEQITDFGFKF------------ 3030
Query: 584 DHGGCEHRCVNTLGSYKCACDPGYELAADKKMCEVACGGFITKLNGTITSPGWP-KEYPT 642
SY+ ++CGG +G ITSP + +YP
Sbjct: 3031 --------------SYRI----------------ISCGGVFNFSSGIITSPAYSYADYPN 3060
Query: 643 NKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVEVRSGLSPDAKLHGRFCGSETPEV 702
+ +C++ + I L+F F++ + C +D++ + G + L G+FCGS+ P
Sbjct: 3061 DMHCLYTITVSDDKVIELKFSDFDVVPSTSCSHDYLAIYDGANTSDPLLGKFCGSKRPPN 3120
Query: 703 ITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECAKDNGGCQHECVNTFGSYLCRCRNGY 762
+ S +N+M + FK+D+ + +G++ F + G Q C G YL N
Sbjct: 3121 VKSSNNSMLLVFKTDSFQTAKGWKMSF--------RQTLGPQQGC----GGYLTGSNN-- 3166
Query: 763 WLHENGHDCKEAGCAHKISSVEGTLASPNWPDK--YPSRRECTWNISSTAGHRVKLTFNE 820
T ASP+ Y C W I + + LTFN
Sbjct: 3167 -----------------------TFASPDSDSNGMYDKNLNCVWIIIAPVNKVIHLTFNT 3203
Query: 821 FEIE---QHQECAYDHLEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQ 877
F +E Q C YD++++YDG A + G FCGS P P ++SG+ + ++F SD +++
Sbjct: 3204 FALEAASTRQRCLYDYVKLYDGDSENANLAGTFCGSTVPAPFISSGNFLTVQFISDLTLE 3263
Query: 878 RKGFQAVHS---TECGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELT 934
R+GF A ++ CGG A T + S D + P C WVI + V++T
Sbjct: 3264 REGFNATYTIMDMPCGGTYNA-TWTPQNISSPNSSDPDVPFSI-CTWVIDSPPHQQVKIT 3321
Query: 935 FRTFEVEEEADCGYDYMEAYDGYDSSAPRLGRFCG--SGPLEEIYSAGDSLMIRFRT 989
++ + DC +Y++ D +FCG + + YS+ + M+ F++
Sbjct: 3322 VWALQLTSQ-DCTQNYLQLQDSPQGHGNSRFQFCGRNASAVPVFYSSMSTAMVIFKS 3377
Score = 191 bits (486), Expect = 2e-48
Identities = 130/544 (23%), Positives = 218/544 (40%), Gaps = 87/544 (15%)
Query: 461 EATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYD 520
+ CG ++ G + Y C W I G + +TF F +E D+C ++
Sbjct: 471 QQVCGESLSGINGSFSYRSPDVGYVHDVNCFWVIKTEMGKVLRITFTFFRLESMDNCPHE 530
Query: 521 YLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDEC 580
+L+V DG + + +G FCG P ++ SS N L+ S+ N GF + + E
Sbjct: 531 FLQVYDGDSSSAFQLGRFCGSSLPHELLSSDNALYFHLYSEHLRNGRGFTVRWETQQPE- 589
Query: 581 SWPDHGGCEHRCVNTLGSYKCACDPGYELAADKKMCEVACGGFITKLNGTITSPGWPKEY 640
CGG +T G+I SPG+P Y
Sbjct: 590 ---------------------------------------CGGILTGPYGSIKSPGYPGNY 610
Query: 641 PTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVEVRSGLSPDAKLHGRFCGSETP 700
P ++CVW VV ++ F LE +D C D++E+R G L G+FC + +
Sbjct: 611 PPGRDCVWIVVTSPDLLVTFTFGTLSLEHHDDCNKDYLEIRDGPLYQDPLLGKFCTTFSV 670
Query: 701 EVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECAKDNGGCQHECVNTFGSYLCRCRN 760
+ + R+ F SD+ +S +GF + + + RC
Sbjct: 671 PPLQTTGPFARIHFHSDSQISDQGFHITYLTSPSD--------------------LRCGG 710
Query: 761 GYWLHENGHDCKEAGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNE 820
Y + EG L P + R+C + + G ++++ F
Sbjct: 711 NY------------------TDPEGELFLPELSGPFTHTRQCVYMMKQPQGEQIQINFTH 752
Query: 821 FEIEQHQECAYDHLEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKG 880
E++ + + +++E+ DG +LG+ CG+ + +S+++RF DASV++
Sbjct: 753 VELQCQSDSSQNYIEVRDG----ETLLGKVCGNGTISHIKSITNSVWIRFKIDASVEKAS 808
Query: 881 FQAVHSTECGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEV 940
F+AV+ CG L T E + F N YP E C W I + L F FE+
Sbjct: 809 FRAVYQVACGDEL-----TGEGVIRSPFFPNVYPGERTCRWTIHQPQSQVILLNFTVFEI 863
Query: 941 EEEADCGYDYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHA 1000
A C DY+E +P ++CG+ I S + L + F + GF A
Sbjct: 864 GSSAHCETDYVEIGSSSILGSPENKKYCGTDIPSFITSVYNFLYVTFVKSSSTENHGFMA 923
Query: 1001 RYTS 1004
++++
Sbjct: 924 KFSA 927
Score = 162 bits (409), Expect = 2e-39
Identities = 109/422 (25%), Positives = 183/422 (43%), Gaps = 66/422 (15%)
Query: 592 CVNTLGSYKCACDPGYELAADKKMCEV---ACGGFITKLNGTITSPGWPKEYPTNKNCVW 648
CV+ + S+ C C + A +C+V CG ++ +NG+ + Y + NC W
Sbjct: 447 CVDGVDSFSCECTRLWTGA----LCQVPQQVCGESLSGINGSFSYRSPDVGYVHDVNCFW 502
Query: 649 QVVAPAQYRISLQFEVFELEGNDVCKYDFVEVRSGLSPDAKLHGRFCGSETPEVITSQSN 708
+ + + F F LE D C ++F++V G S A GRFCGS P + S N
Sbjct: 503 VIKTEMGKVLRITFTFFRLESMDNCPHEFLQVYDGDSSSAFQLGRFCGSSLPHELLSSDN 562
Query: 709 NMRVEFKSDNTVSKRGFRAHFFSDKDECAKDNGGCQHECVNTFGSYLCRCRNGYWLHENG 768
+ S++ + RGF + + + EC GG
Sbjct: 563 ALYFHLYSEHLRNGRGFTVRWETQQPEC----GGI------------------------- 593
Query: 769 HDCKEAGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQE 828
++ G++ SP +P YP R+C W + ++ V TF +E H +
Sbjct: 594 -----------LTGPYGSIKSPGYPGNYPPGRDCVWIVVTSPDLLVTFTFGTLSLEHHDD 642
Query: 829 CAYDHLEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQAVHST- 887
C D+LE+ DGP P+LG+FC + P +G + F+SD+ + +GF + T
Sbjct: 643 CNKDYLEIRDGPLYQDPLLGKFCTTFSVPPLQTTGPFARIHFHSDSQISDQGFHITYLTS 702
Query: 888 ----ECGGRL---KAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEV 940
CGG + E+ EL + +C +++ G +++ F E+
Sbjct: 703 PSDLRCGGNYTDPEGELFLPEL-------SGPFTHTRQCVYMMKQPQGEQIQINFTHVEL 755
Query: 941 EEEADCGYDYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHA 1000
+ ++D +Y+E DG LG+ CG+G + I S +S+ IRF+ D ++ K F A
Sbjct: 756 QCQSDSSQNYIEVRDG----ETLLGKVCGNGTISHIKSITNSVWIRFKIDASVEKASFRA 811
Query: 1001 RY 1002
Y
Sbjct: 812 VY 813
Score = 130 bits (328), Expect = 5e-30
Identities = 113/475 (23%), Positives = 180/475 (37%), Gaps = 84/475 (17%)
Query: 578 DECSWPDHGGCEH--RCVNTLGSYKC-ACDPGYE----LAADKKMCEVACGGFITKLNGT 630
DECS+ G C +C NT GS+ C AC G++ + D CE+ GG +
Sbjct: 265 DECSFQP-GPCSTLVQCFNTQGSFYCGACPTGWQGNGYICEDINECEINNGGC------S 317
Query: 631 ITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVEV-RSGLSPDAK 689
+ P P + +C Q P ++ +G D V G PDA
Sbjct: 318 VAPPVECVNTPGSSHC--QACPPG----------YQGDGRVCTLTDICSVSNGGCHPDAS 365
Query: 690 LHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECAKDNGGCQHECVN 749
+ + N G+ + + +C++
Sbjct: 366 CSSTLGSLPLCTCLPGYTGN--------------GYGPNGCVQLSNICLSHPCLNGQCID 411
Query: 750 TFGSYLCRCRNGYW---LHENGHDC---------------------------------KE 773
T Y C+C +G+ EN ++C +
Sbjct: 412 TVSGYFCKCDSGWTGVNCTENINECLSNPCLNGGTCVDGVDSFSCECTRLWTGALCQVPQ 471
Query: 774 AGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDH 833
C +S + G+ + + Y C W I + G +++TF F +E C ++
Sbjct: 472 QVCGESLSGINGSFSYRSPDVGYVHDVNCFWVIKTEMGKVLRITFTFFRLESMDNCPHEF 531
Query: 834 LEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQAVHST---ECG 890
L++YDG S A LGRFCGS P ++S ++++ YS+ +GF T ECG
Sbjct: 532 LQVYDGDSSSAFQLGRFCGSSLPHELLSSDNALYFHLYSEHLRNGRGFTVRWETQQPECG 591
Query: 891 GRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGYDY 950
G L + + + NYP C W++V V TF T +E DC DY
Sbjct: 592 GILTGPYGSIKSPGY----PGNYPPGRDCVWIVVTSPDLLVTFTFGTLSLEHHDDCNKDY 647
Query: 951 MEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARYTST 1005
+E DG P LG+FC + + + + G I F +D I+ +GFH Y ++
Sbjct: 648 LEIRDGPLYQDPLLGKFCTTFSVPPLQTTGPFARIHFHSDSQISDQGFHITYLTS 702
Score = 37.0 bits (84), Expect = 0.094
Identities = 58/215 (26%), Positives = 79/215 (36%), Gaps = 49/215 (22%)
Query: 592 CVNTLGSYKCACDP---GYELAADKKMCEVACGGFITKLNGTITSPGWPKEYPTNKNCVW 648
CVNT+GSY C C P G + A+ CE GG + + CV
Sbjct: 190 CVNTMGSYSCHCPPETYGPQCASKYDDCE---GGSVAR-------------------CVH 227
Query: 649 QVVAPAQYRISLQFEVFELEGNDVCKYDFVEVRSGLSPDAKLHGRFCGSETPEVITS-QS 707
+ ++ + E + + VC D + S SP L C + T Q
Sbjct: 228 GICEDL-----MREQAGEPKYSCVC--DAGWMFSPNSPACTLDRDECSFQPGPCSTLVQC 280
Query: 708 NNMRVEFKSDNTVSKRGFRAHFFSDKDECAKDNGGCQ----HECVNTFGSYLCR-CRNGY 762
N + F + + D +EC +NGGC ECVNT GS C+ C GY
Sbjct: 281 FNTQGSFYCGACPTGWQGNGYICEDINECEINNGGCSVAPPVECVNTPGSSHCQACPPGY 340
Query: 763 WLHENGHDC--------KEAGCAHKISSVEGTLAS 789
+G C GC H +S TL S
Sbjct: 341 --QGDGRVCTLTDICSVSNGGC-HPDASCSSTLGS 372
>gi|72384339 CUB domain containing protein 2 [Homo sapiens]
Length = 449
Score = 225 bits (573), Expect = 2e-58
Identities = 136/450 (30%), Positives = 208/450 (46%), Gaps = 96/450 (21%)
Query: 451 ILGKGFFA-AYEAT-CGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQA 508
+LG G A A E CGG ++ +G SPN+P Y + EC W I V+EG V LTF A
Sbjct: 15 LLGPGLQAQAMEGVKCGGVLSAPSGNFSSPNFPRLYPYNTECSWLIVVAEGSSVLLTFHA 74
Query: 509 FEIERHDSCAYDYLEVRDGPT-EESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKA 567
F++E HD+C++D+LE+ +G + ++ L+G FCG P SS + + + F SD +
Sbjct: 75 FDLEYHDTCSFDFLEIYNGASPDKGNLLGRFCGKVPPPPFTSSWHVMSVIFHSDKHVASH 134
Query: 568 GFAANFFKEVDECSWPDHGGCEHRCVNTLGSYKCACDPGYELAADKKMCEVACGGFITKL 627
GF+A + K+V CGG +T L
Sbjct: 135 GFSAGYQKDV------------------------------------------CGGVLTGL 152
Query: 628 NGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVEVRSGLSPD 687
+G +TSP +P YP + C W + A + L F F++EGN+ C YD+V V G P
Sbjct: 153 SGVLTSPEYPNNYPNSMECHWVIRAAGPAHVKLVFVDFQVEGNEECTYDYVAVLGGPGPT 212
Query: 688 AKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECAKDNGGCQHEC 747
H +CGS P + S + ++V FKSD + RGF+A++FS +
Sbjct: 213 RGHH--YCGSTRPPTLVSLGHELQVVFKSDFNIGGRGFKAYYFSGE-------------- 256
Query: 748 VNTFGSYLCRCRNGYWLHENGHDCKEAGCAHKISSVEGTLASPNWPDKYPSRRECTWNIS 807
C ++ G +SP +P YP+ C W I
Sbjct: 257 ----------------------------CQEVYMAMRGNFSSPQYPSSYPNNIRCHWTIR 288
Query: 808 STAGHRVKLTFNEFEIEQ----HQECAYDHLEMYDGPDSLAPILGRFCGSKKPDPTVASG 863
G++VK+ F + ++E+ + C +DHL +DG AP+LG +CG P P +S
Sbjct: 289 LPPGYQVKVFFLDLDLEEPNSLTKTCDFDHLAAFDGASEEAPLLGNWCGHHLPPPVTSSH 348
Query: 864 SSMFLRFYSDASVQRKGFQAVHSTECGGRL 893
+ + L ++D S R+GF + GG+L
Sbjct: 349 NQLLLLLHTDRSTTRRGFSVAY---IGGQL 375
Score = 202 bits (514), Expect = 1e-51
Identities = 127/405 (31%), Positives = 195/405 (48%), Gaps = 59/405 (14%)
Query: 605 PGYELAADKKMCEVACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEV 664
PG + A M V CGG ++ +G +SP +P+ YP N C W +V + L F
Sbjct: 18 PGLQAQA---MEGVKCGGVLSAPSGNFSSPNFPRLYPYNTECSWLIVVAEGSSVLLTFHA 74
Query: 665 FELEGNDVCKYDFVEVRSGLSPD-AKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKR 723
F+LE +D C +DF+E+ +G SPD L GRFCG P TS + M V F SD V+
Sbjct: 75 FDLEYHDTCSFDFLEIYNGASPDKGNLLGRFCGKVPPPPFTSSWHVMSVIFHSDKHVASH 134
Query: 724 GFRAHFFSDKDECAKDNGGCQHECVNTFGSYLCRCRNGYWLHENGHDCKEAGCAHKISSV 783
GF A + KD C GG ++ +
Sbjct: 135 GFSAGY--QKDVC----GGV------------------------------------LTGL 152
Query: 784 EGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMYDGPDSL 843
G L SP +P+ YP+ EC W I + VKL F +F++E ++EC YD++ + GP
Sbjct: 153 SGVLTSPEYPNNYPNSMECHWVIRAAGPAHVKLVFVDFQVEGNEECTYDYVAVLGGP--- 209
Query: 844 APILGR-FCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQAVH-STECGGRLKAEVQTKE 901
P G +CGS +P V+ G + + F SD ++ +GF+A + S EC + + +
Sbjct: 210 GPTRGHHYCGSTRPPTLVSLGHELQVVFKSDFNIGGRGFKAYYFSGECQ---EVYMAMRG 266
Query: 902 LYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEAD----CGYDYMEAYDGY 957
+S Q+ ++YP+ RC W I GY V++ F ++EE C +D++ A+DG
Sbjct: 267 NFSSPQY-PSSYPNNIRCHWTIRLPPGYQVKVFFLDLDLEEPNSLTKTCDFDHLAAFDGA 325
Query: 958 DSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARY 1002
AP LG +CG + S+ + L++ TD + ++GF Y
Sbjct: 326 SEEAPLLGNWCGHHLPPPVTSSHNQLLLLLHTDRSTTRRGFSVAY 370
Score = 193 bits (491), Expect = 6e-49
Identities = 124/409 (30%), Positives = 181/409 (44%), Gaps = 53/409 (12%)
Query: 334 LSQGDIAQARKLYKCPACGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNF 393
L G AQA + KC G L +GNFS+P FP YP + C W I V G ++L F
Sbjct: 16 LGPGLQAQAMEGVKC---GGVLSAPSGNFSSPNFPRLYPYNTECSWLIVVAEGSSVLLTF 72
Query: 394 TSMDLFKSRLCWYDYVEVRDGYWR-KAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNIL 452
+ DL C +D++E+ +G K LLGRFCG P P S+ + V F S ++
Sbjct: 73 HAFDLEYHDTCSFDFLEIYNGASPDKGNLLGRFCGKVPPPPFTSSWHVMSVIFHSDKHVA 132
Query: 453 GKGFFAAYEA-TCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEI 511
GF A Y+ CGG + +G + SP YP++Y S EC W I + HV L F F++
Sbjct: 133 SHGFSAGYQKDVCGGVLTGLSGVLTSPEYPNNYPNSMECHWVIRAAGPAHVKLVFVDFQV 192
Query: 512 ERHDSCAYDYLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAA 571
E ++ C YDY+ V GP H+CG +P + S + L + F SD +I GF A
Sbjct: 193 EGNEECTYDYVAVLGGPGPTRG--HHYCGSTRPPTLVSLGHELQVVFKSDFNIGGRGFKA 250
Query: 572 NFFKEVDECSWPDHGGCEHRCVNTLGSYKCACDPGYELAADKKMCEVACGGFITKLNGTI 631
+F G C+ + G
Sbjct: 251 YYFS----------GECQE--------------------------------VYMAMRGNF 268
Query: 632 TSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEG----NDVCKYDFVEVRSGLSPD 687
+SP +P YP N C W + P Y++ + F +LE C +D + G S +
Sbjct: 269 SSPQYPSSYPNNIRCHWTIRLPPGYQVKVFFLDLDLEEPNSLTKTCDFDHLAAFDGASEE 328
Query: 688 AKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDEC 736
A L G +CG P +TS N + + +D + ++RGF + + C
Sbjct: 329 APLLGNWCGHHLPPPVTSSHNQLLLLLHTDRSTTRRGFSVAYIGGQLGC 377
Score = 144 bits (363), Expect = 4e-34
Identities = 89/239 (37%), Positives = 121/239 (50%), Gaps = 14/239 (5%)
Query: 776 CAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLE 835
C +S+ G +SPN+P YP EC+W I G V LTF+ F++E H C++D LE
Sbjct: 30 CGGVLSAPSGNFSSPNFPRLYPYNTECSWLIVVAEGSSVLLTFHAFDLEYHDTCSFDFLE 89
Query: 836 MYDG--PDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQAVHSTE-CGGR 892
+Y+G PD +LGRFCG P P +S M + F+SD V GF A + + CGG
Sbjct: 90 IYNGASPDK-GNLLGRFCGKVPPPPFTSSWHVMSVIFHSDKHVASHGFSAGYQKDVCGGV 148
Query: 893 LK--AEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGYDY 950
L + V T Y NNYP+ C WVI A V+L F F+VE +C YDY
Sbjct: 149 LTGLSGVLTSPEY------PNNYPNSMECHWVIRAAGPAHVKLVFVDFQVEGNEECTYDY 202
Query: 951 MEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARYTSTKFQD 1009
+ G R +CGS + S G L + F++D I +GF A Y S + Q+
Sbjct: 203 VAVLGG--PGPTRGHHYCGSTRPPTLVSLGHELQVVFKSDFNIGGRGFKAYYFSGECQE 259
>gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens]
Length = 3565
Score = 214 bits (545), Expect = 3e-55
Identities = 169/648 (26%), Positives = 282/648 (43%), Gaps = 127/648 (19%)
Query: 464 CGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDYLE 523
C G+ + G I SP YP+ Y + C+W+I V+EG + + +F E++ +D LE
Sbjct: 1803 CSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQN----WDSLE 1858
Query: 524 VRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANF----FKEVDE 579
+ DG + +G F G P + S+SN+L++ F SD S+ AGF + E
Sbjct: 1859 IHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLEYKTVGLAACQE 1918
Query: 580 CSWPDHGGC--EHRCVNTLGSYKCACDPGYELAA----------------DKKMCEVACG 621
+ P + + VN + S++C +PGY L +C CG
Sbjct: 1919 PALPSNSIKIGDRYMVNDVLSFQC--EPGYTLQGRSHISCMPGTVRRWNYPSPLCIATCG 1976
Query: 622 GFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVEVR 681
G ++ L G I SPG+P YP N +C W++ P Y +QF F E N +DF+E++
Sbjct: 1977 GTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEAN----HDFLEIQ 2032
Query: 682 SGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECAKD-- 739
+G + + G+F G++ P + S ++ + F SD++ +++GF+ + + + + D
Sbjct: 2033 NGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQNCPDPP 2092
Query: 740 ---NGGCQHECVNTFGSYLCRCRNGYWLHENGH---DCK--------------EAGCAHK 779
NG + + S C GY L GH C+ +A C +
Sbjct: 2093 PFQNGYMINSDYSVGQSVSFECYPGYIL--IGHPVLTCQHGINRNWNYPFPRCDAPCGYN 2150
Query: 780 ISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMYDG 839
++S GT+ SP +PD+YP ++C W I+ GH V + F + E D++ ++DG
Sbjct: 2151 VTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQ----TEAVNDYIAVWDG 2206
Query: 840 PDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDAS-----------VQRKGFQAVHST- 887
PD +P LG F G+ + +S + + L+F+SD S Q K Q +
Sbjct: 2207 PDQNSPQLGVFSGNTALETAYSSTNQVLLKFHSDFSNGGFFVLNFHAFQLKKCQPPPAVP 2266
Query: 888 -----------ECGGRLK-----------AEVQTKELYSHAQFGDNNYPSEARC------ 919
E G +K ++ T +L S QF + EA+C
Sbjct: 2267 QAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCEAQCPANEVR 2326
Query: 920 ----------------------DWVIVAEDGYGVELTFRTFEVEEEADCGYDYMEAYDGY 957
W I E Y + + TF+ E++ +D +E +DG
Sbjct: 2327 TGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQ----FDALEVFDGS 2382
Query: 958 DSSAPRLGRFCGSGPLEEIY-SAGDSLMIRFRTDDTINKKGFHARYTS 1004
+P L G+ + + S + L +R+ TD +KKGF RY +
Sbjct: 2383 SGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAA 2430
Score = 204 bits (520), Expect = 3e-52
Identities = 172/650 (26%), Positives = 275/650 (42%), Gaps = 126/650 (19%)
Query: 462 ATCGGDMNK-DAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYD 520
A CGG ++ +G+I SP YP Y + C W I G + L F F+ E A+D
Sbjct: 1276 AECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTEM----AHD 1331
Query: 521 YLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEV--- 577
L+V DGP + L+ + G PED+ S+ N L ++F SD I+K+GF+ F +
Sbjct: 1332 ILKVWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIAAT 1391
Query: 578 -DECSWPDHGGCEHRCVNTLGSYKCACDPGYELAADKKM-----------------CEVA 619
++ P +G + CDPGY+L K+ C A
Sbjct: 1392 CNDPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTCIAA 1451
Query: 620 CGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVE 679
CGG +T G I SP +P+ YP K C W+V + I+L F+ F +E + YDF+
Sbjct: 1452 CGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEPS----YDFLH 1507
Query: 680 VRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECAKD 739
+ G ++ L G + GS+ PE I S N++ + F+SD +V GF F E D
Sbjct: 1508 IYEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEFKEKPREACFD 1567
Query: 740 NGGCQHEC-VNT---FGSYLC-RCRNGYWLHEN-------GHDCK----------EAGCA 777
G + V T GS + +C +GY + + G D K A C
Sbjct: 1568 PGNIMNGTRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSCNAPCG 1627
Query: 778 HKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMY 837
+ + EG + SPN+P Y + + C ++I+ + + F +F Q D E++
Sbjct: 1628 GQYTGSEGVVLSPNYPHNYTAGQICLYSITVP---KEFVVFGQF--AYFQTALNDLAELF 1682
Query: 838 DGPDSLAPILGRFCGSKKPDP-TVASGSSMFLRFYSDASVQRKGFQAVH-------STEC 889
DG + A +L GS + +A+ + + LRF + + +GF V+ T+C
Sbjct: 1683 DGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGFHFVYQAVPRTSDTQC 1742
Query: 890 --------GGRLKAEVQTKELY-----------------------SHAQFGDN------- 911
G R+ +E + + AQ+ D
Sbjct: 1743 SSVPEPRYGRRIGSEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTIPSCVVP 1802
Query: 912 ---------------NYP----SEARCDWVIVAEDGYGVELTFRTFEVEEEADCGYDYME 952
YP + C W I+ +G G+++ +F E+ +D +E
Sbjct: 1803 CSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQ----NWDSLE 1858
Query: 953 AYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARY 1002
+DG D +APRLG F G+ + S + L + F++D ++ GFH Y
Sbjct: 1859 IHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLEY 1908
Score = 197 bits (502), Expect = 3e-50
Identities = 176/661 (26%), Positives = 274/661 (41%), Gaps = 123/661 (18%)
Query: 450 NILGKGFFAAYEATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAF 509
N++ EA CGG + +G I P +P Y+ S C W I G + +TF F
Sbjct: 745 NVVWSSTVPRCEAPCGGHLTASSGVILPPGWPGYYKDSLHCEWIIEAKPGHSIKITFDRF 804
Query: 510 EIERHDSCAYDYLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGF 569
+ E + YD LEVRDGP S LIG + G + P+ + S+ N +++ F +D S + GF
Sbjct: 805 QTEVN----YDTLEVRDGPASSSPLIGEYHGTQAPQFLISTGNFMYLLFTTDNSRSSIGF 860
Query: 570 AANFFK---EVDECSWPDHGGCEHRCVNTLG---SYKCACDPGYELAADKKM-------- 615
++ E D C P HR G + +CDPGY L+ D+ +
Sbjct: 861 LIHYESVTLESDSCLDPGIPVNGHRHGGDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQW 920
Query: 616 ------CEVACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEG 669
C+ CGG+I +GT+ SPG+P YP + NC W + + + F F LE
Sbjct: 921 NHALPSCDALCGGYIQGKSGTVLSPGFPDFYPNSLNCTWTIEVSHGKGVQMIFHTFHLES 980
Query: 670 NDVCKYDFVEVRSGLSPDAKLHGRFCGSETPEVITS---QSNNMRVEFKSDNTVSKRGFR 726
+ +D++ + S + R GS P I + + ++ F SD ++S GF
Sbjct: 981 S----HDYLLITEDGSFSEPV-ARLTGSVLPHTIKAGLFGNFTAQLRFISDFSISYEGFN 1035
Query: 727 AHFFSDKDECAKDNG--GCQHECVNTFG---SYLCRCRNGYWLH-ENGHDCKEAG----- 775
F E D G FG S C GY L C G
Sbjct: 1036 ITFSEYDLEPCDDPGVPAFSRRIGFHFGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVWS 1095
Query: 776 ---------CAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQH 826
C + EGTL SPN+P Y + EC + I + AG + L F++ +
Sbjct: 1096 APLPRCVAECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQLFEG 1155
Query: 827 QECAYDHLEMYDGPDSLAPILGRFCGSKKPDPTVASGSS-MFLRFYSDASVQRKGFQAVH 885
D L++YDG DS + LG F ++ + S S+ ++L F ++ S +GFQ +
Sbjct: 1156 -----DTLKVYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQGFQLTY 1210
Query: 886 ST----EC--------GGRLKAE---VQTKELYS----HAQFGDNN-------------- 912
++ +C G R++ E T LYS +A G N
Sbjct: 1211 TSFDLVKCEDPGIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNTLTCLSGDRRVWDKP 1270
Query: 913 ----------------------------YPSEARCDWVIVAEDGYGVELTFRTFEVEEEA 944
Y + C W+I A+ G + L F F+ E
Sbjct: 1271 LPSCIAECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTE--- 1327
Query: 945 DCGYDYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARYTS 1004
+D ++ +DG S L + GS E+I+S +SL ++F +D I+K GF ++++
Sbjct: 1328 -MAHDILKVWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFST 1386
Query: 1005 T 1005
+
Sbjct: 1387 S 1387
Score = 197 bits (501), Expect = 4e-50
Identities = 138/464 (29%), Positives = 221/464 (47%), Gaps = 59/464 (12%)
Query: 463 TCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHV-GLTFQAFEIERHDSCAYDY 521
TCG ++ +G I SPNYP Y + CVW IT ++ V L F+ FE+ER YD
Sbjct: 411 TCGSNLRGPSGVITSPNYPVQYEDNAHCVWVITTTDPDKVIKLAFEEFELER----GYDT 466
Query: 522 LEVRDGPT--EESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDE 579
L V D + +++ G P+ + S SN++W+ SD SI GF A ++E+++
Sbjct: 467 LTVGDAGKVGDTRSVLYVLTGSSVPDLIVSMSNQMWLHLQSDDSIGSPGFKA-VYQEIEK 525
Query: 580 CSWPDHG--------GCEHRCVNTLGSYKC------------ACDPGYELAADKKMCEVA 619
D G G +TL +++C C + + +K C +
Sbjct: 526 GGCGDPGIPAYGKRTGSSFLHGDTL-TFECPAAFELVGERVITCQQNNQWSGNKPSCVFS 584
Query: 620 CGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVE 679
C T +G I SP +P+EY N NCVW +++ RI L F F++E ++DF+
Sbjct: 585 CFFNFTASSGIILSPNYPEEYGNNMNCVWLIISEPGSRIHLIFNDFDVEP----QFDFLA 640
Query: 680 VRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFS-DKDECAK 738
V+ D + G F G+E P + S + +R+EF+SD++ + RGF + + ++EC
Sbjct: 641 VKDDGISDITVLGTFSGNEVPSQLASSGHIVRLEFQSDHSTTGRGFNITYTTFGQNECHD 700
Query: 739 D----NG---------------GCQHECVNTFG--SYLCRCRNGYWLHENGHDCKEAGCA 777
NG C V T G S C ++G + + EA C
Sbjct: 701 PGIPINGRRFGDRFLLGSSVSFHCDDGFVKTQGSESITCILQDGNVVWSSTVPRCEAPCG 760
Query: 778 HKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMY 837
+++ G + P WP Y C W I + GH +K+TF+ F+ E + YD LE+
Sbjct: 761 GHLTASSGVILPPGWPGYYKDSLHCEWIIEAKPGHSIKITFDRFQTEVN----YDTLEVR 816
Query: 838 DGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGF 881
DGP S +P++G + G++ P +++G+ M+L F +D S GF
Sbjct: 817 DGPASSSPLIGEYHGTQAPQFLISTGNFMYLLFTTDNSRSSIGF 860
Score = 190 bits (483), Expect = 5e-48
Identities = 164/637 (25%), Positives = 258/637 (40%), Gaps = 128/637 (20%)
Query: 462 ATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDY 521
A CGG G + SPNYP +Y + C++ ITV + F V F F+ + D
Sbjct: 1624 APCGGQYTGSEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQ-----TALNDL 1678
Query: 522 LEVRDGPTEESALIGHFCGYEKPEDVK-SSSNRLWMKFVSDGSINKAGFAANFFKEVDEC 580
E+ DG ++ L+ G E + ++SN++ ++F + + GF +
Sbjct: 1679 AELFDGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGFHFVYQAVPRTS 1738
Query: 581 SWPDHGGCEHRCVNTLGSYKCA-------CDPGYELAADKKM------------------ 615
E R +GS A C+PGY L +
Sbjct: 1739 DTQCSSVPEPRYGRRIGSEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTIPS 1798
Query: 616 CEVACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKY 675
C V C G T+ GTI SPG+P+ Y N NC+W+++ I +Q F E N +
Sbjct: 1799 CVVPCSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQN----W 1854
Query: 676 DFVEVRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHF----FS 731
D +E+ G A G F G+ P ++ S SN + + F+SD +V+ GF + +
Sbjct: 1855 DSLEIHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLEYKTVGLA 1914
Query: 732 DKDECAKDNGGCQ---HECVNTFGSYLCRCRNGYWLHENGH-DCKE-------------- 773
E A + + VN S+ +C GY L H C
Sbjct: 1915 ACQEPALPSNSIKIGDRYMVNDVLSF--QCEPGYTLQGRSHISCMPGTVRRWNYPSPLCI 1972
Query: 774 AGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDH 833
A C +S++ G + SP +P YP+ +CTW IS G+ + F F E + +D
Sbjct: 1973 ATCGGTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEAN----HDF 2028
Query: 834 LEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGF----QAVHSTEC 889
LE+ +GP +P++G+F G+ P +++ + FYSD S R+GF QA C
Sbjct: 2029 LEIQNGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQNC 2088
Query: 890 --------GGRLKAEVQTKELYSH---------------AQFGDN---NYPSEARCD--- 920
G + ++ + S Q G N NYP RCD
Sbjct: 2089 PDPPPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPF-PRCDAPC 2147
Query: 921 ---------------------------WVIVAEDGYGVELTFRTFEVEEEADCGYDYMEA 953
W+I G+GV + F + E DY+
Sbjct: 2148 GYNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTE----AVNDYIAV 2203
Query: 954 YDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTD 990
+DG D ++P+LG F G+ LE YS+ + ++++F +D
Sbjct: 2204 WDGPDQNSPQLGVFSGNTALETAYSSTNQVLLKFHSD 2240
Score = 183 bits (464), Expect = 8e-46
Identities = 175/670 (26%), Positives = 267/670 (39%), Gaps = 134/670 (20%)
Query: 330 QRVRLSQGDIAQARKLYKCPACGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKI 389
QRV + + R + + CG L+ +G ++P +P Y +HCVW I+ T +K+
Sbjct: 391 QRVTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNYPVQYEDNAHCVWVITTTDPDKV 450
Query: 390 V-LNFTSMDLFKSRLCWYDYVEVRDG--YWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFR 446
+ L F +L + YD + V D +L G +P+ +VS +++W+ +
Sbjct: 451 IKLAFEEFELERG----YDTLTVGDAGKVGDTRSVLYVLTGSSVPDLIVSMSNQMWLHLQ 506
Query: 447 SSSNILGKGFFAAYE----ATCG-----------------GD------------MNKDAG 473
S +I GF A Y+ CG GD + +
Sbjct: 507 SDDSIGSPGFKAVYQEIEKGGCGDPGIPAYGKRTGSSFLHGDTLTFECPAAFELVGERVI 566
Query: 474 QIQSPNYPDDYRPS--KECVWRITVSEGF--------------------------HVGLT 505
Q N +PS C + T S G + L
Sbjct: 567 TCQQNNQWSGNKPSCVFSCFFNFTASSGIILSPNYPEEYGNNMNCVWLIISEPGSRIHLI 626
Query: 506 FQAFEIERHDSCAYDYLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSIN 565
F F++E +D+L V+D + ++G F G E P + SS + + ++F SD S
Sbjct: 627 FNDFDVEPQ----FDFLAVKDDGISDITVLGTFSGNEVPSQLASSGHIVRLEFQSDHSTT 682
Query: 566 KAGFAANFF----KEVDECSWPDHG---------------GCEHRCVNTLGSYKCAC--- 603
GF + E + P +G C+ V T GS C
Sbjct: 683 GRGFNITYTTFGQNECHDPGIPINGRRFGDRFLLGSSVSFHCDDGFVKTQGSESITCILQ 742
Query: 604 DPGYELAADKKMCEVACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFE 663
D ++ CE CGG +T +G I PGWP Y + +C W + A + I + F+
Sbjct: 743 DGNVVWSSTVPRCEAPCGGHLTASSGVILPPGWPGYYKDSLHCEWIIEAKPGHSIKITFD 802
Query: 664 VFELEGNDVCKYDFVEVRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKR 723
F+ E N YD +EVR G + + L G + G++ P+ + S N M + F +DN+ S
Sbjct: 803 RFQTEVN----YDTLEVRDGPASSSPLIGEYHGTQAPQFLISTGNFMYLLFTTDNSRSSI 858
Query: 724 GFRAHFFS---DKDECAKD----NGGCQHECVNTFG---SYLCRCRNGYWL--------- 764
GF H+ S + D C NG H FG + C GY L
Sbjct: 859 GFLIHYESVTLESDSCLDPGIPVNG---HRHGGDFGIRSTVTFSCDPGYTLSDDEPLVCE 915
Query: 765 --HENGH---DCKEAGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFN 819
H+ H C +A C I GT+ SP +PD YP+ CTW I + G V++ F+
Sbjct: 916 RNHQWNHALPSC-DALCGGYIQGKSGTVLSPGFPDFYPNSLNCTWTIEVSHGKGVQMIFH 974
Query: 820 EFEIEQHQECAYDHLEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMF---LRFYSDASV 876
F H E ++D+L + + P+ R GS P A F LRF SD S+
Sbjct: 975 TF----HLESSHDYLLITEDGSFSEPV-ARLTGSVLPHTIKAGLFGNFTAQLRFISDFSI 1029
Query: 877 QRKGFQAVHS 886
+GF S
Sbjct: 1030 SYEGFNITFS 1039
Score = 182 bits (463), Expect = 1e-45
Identities = 136/466 (29%), Positives = 212/466 (45%), Gaps = 61/466 (13%)
Query: 462 ATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDY 521
A CG + + G + SPN+P +Y + EC+++I G + L ++F++ D+
Sbjct: 1103 AECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQLFEGDT----- 1157
Query: 522 LEVRDGPTEESALIGHFCGYEKPEDV-KSSSNRLWMKFVSDGSINKAGFAANFFK----E 576
L+V DG S +G F E + S+SN LW++F ++GS GF + +
Sbjct: 1158 LKVYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQGFQLTYTSFDLVK 1217
Query: 577 VDECSWPDHG---GCEHRCVNTLGSYKCACDPGYE---------LAADKKM-------CE 617
++ P++G E +T+ Y +C+PGY L+ D+++ C
Sbjct: 1218 CEDPGIPNYGYRIRDEGHFTDTVVLY--SCNPGYAMHGSNTLTCLSGDRRVWDKPLPSCI 1275
Query: 618 VACGGFI-TKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYD 676
CGG I +G I SPG+P Y N +C W + A ISL F VF+ E +D
Sbjct: 1276 AECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTE----MAHD 1331
Query: 677 FVEVRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSD---- 732
++V G L + GS PE I S N++ ++F SD +SK GF F +
Sbjct: 1332 ILKVWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIAAT 1391
Query: 733 -KDECAKDNGGCQHECVNTFGSYLCRCRNGYWLHENGH-DCKE---------------AG 775
D NG + + +C GY L C + A
Sbjct: 1392 CNDPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTCIAA 1451
Query: 776 CAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLE 835
C ++ G + SPN+P YP +EC W + + L F F +E +YD L
Sbjct: 1452 CGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEP----SYDFLH 1507
Query: 836 MYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGF 881
+Y+G DS +P++G + GS+ P+ +SG+S+FL F SDASV GF
Sbjct: 1508 IYEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGF 1553
Score = 179 bits (454), Expect = 1e-44
Identities = 162/642 (25%), Positives = 265/642 (41%), Gaps = 129/642 (20%)
Query: 351 CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVE 410
C G +PG+P Y + +C+W+I VT G I + S F + W D +E
Sbjct: 1803 CSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVIS---FATEQNW-DSLE 1858
Query: 411 VRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYE----ATCG- 465
+ DG AP LG F G +P L ST ++L++ F+S ++ GF Y+ A C
Sbjct: 1859 IHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLEYKTVGLAACQE 1918
Query: 466 ----------GD--MNKDA---------------------GQIQSPNYPD---------- 482
GD M D G ++ NYP
Sbjct: 1919 PALPSNSIKIGDRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSPLCIATCGGT 1978
Query: 483 ---------------DYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDYLEVRDG 527
Y + +C WRI++ G+ + F F E + +D+LE+++G
Sbjct: 1979 LSTLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEAN----HDFLEIQNG 2034
Query: 528 PTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANF-FKEVDECSWP--- 583
P S +IG F G + P + S+++ + F SD S N+ GF + E+ C P
Sbjct: 2035 PYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQNCPDPPPF 2094
Query: 584 DHGGCEHRCVNTLGSYKCACDPGYELAADKKM----------------CEVACGGFITKL 627
+G + + S C PGY L + C+ CG +T
Sbjct: 2095 QNGYMINSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRCDAPCGYNVTSQ 2154
Query: 628 NGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVEVRSGLSPD 687
NGTI SPG+P EYP K+C+W + P + + + F + + E + D++ V G +
Sbjct: 2155 NGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAVN----DYIAVWDGPDQN 2210
Query: 688 AKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGF---RAHFFSDKDECAKDNGGCQ 744
+ G F G+ E S +N + ++F SD S GF H F K +C Q
Sbjct: 2211 SPQLGVFSGNTALETAYSSTNQVLLKFHSD--FSNGGFFVLNFHAFQLK-KCQPPPAVPQ 2267
Query: 745 HECVN-----TFGSYL-CRCRNGYWL---------------HENGHDCKEAGC-AHKI-S 781
E + G ++ +C GY L E EA C A+++ +
Sbjct: 2268 AEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCEAQCPANEVRT 2327
Query: 782 SVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMYDGPD 841
G + SP +P Y + + C+W+I + + + + F+ E+ +D LE++DG
Sbjct: 2328 GSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQ----FDALEVFDGSS 2383
Query: 842 SLAPILGRFCGSKKPDPTVASGSS-MFLRFYSDASVQRKGFQ 882
+P+L G+ S S+ ++LR+ +D + +KGF+
Sbjct: 2384 GQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFK 2425
Score = 154 bits (390), Expect = 3e-37
Identities = 133/509 (26%), Positives = 200/509 (39%), Gaps = 95/509 (18%)
Query: 457 FAAYEATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDS 516
F E CGG + + I SP++P +Y + +C W I G + L F F++E
Sbjct: 201 FCRAEGACGGTLRGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEE--- 257
Query: 517 CAYDYLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANF--- 573
YD+LE+ TE ++ G P V SS N L + F SD + + GF A F
Sbjct: 258 -GYDFLEISG--TEAPSI--WLTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQVK 312
Query: 574 ----FKEVDECSWPDHGGCEHRCVNTLG------------------------------SY 599
K P G V + G +
Sbjct: 313 KAIELKSRGVKMLPSKDGSHKNSVLSQGGVALVSDMCPDPGIPENGRRAGSDFSRVGANV 372
Query: 600 KCACDPGYELAADKKM------------------CEV-ACGGFITKLNGTITSPGWPKEY 640
+ +C+ Y L K + C CG + +G ITSP +P +Y
Sbjct: 373 QFSCEDNYVLQGSKSITCQRVTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNYPVQY 432
Query: 641 PTNKNCVWQVVAPAQYR-ISLQFEVFELEGNDVCKYDFVEVRSG--LSPDAKLHGRFCGS 697
N +CVW + + I L FE FELE YD + V + + GS
Sbjct: 433 EDNAHCVWVITTTDPDKVIKLAFEEFELERG----YDTLTVGDAGKVGDTRSVLYVLTGS 488
Query: 698 ETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFS-DKDECA--------KDNGGC----- 743
P++I S SN M + +SD+++ GF+A + +K C K G
Sbjct: 489 SVPDLIVSMSNQMWLHLQSDDSIGSPGFKAVYQEIEKGGCGDPGIPAYGKRTGSSFLHGD 548
Query: 744 --QHECVNTF---GSYLCRCRNGYWLHENGHDCKEAGCAHKISSVEGTLASPNWPDKYPS 798
EC F G + C+ N C + C ++ G + SPN+P++Y +
Sbjct: 549 TLTFECPAAFELVGERVITCQQNNQWSGNKPSCVFS-CFFNFTASSGIILSPNYPEEYGN 607
Query: 799 RRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMYDGPDSLAPILGRFCGSKKPDP 858
C W I S G R+ L FN+F++E +D L + D S +LG F G++ P
Sbjct: 608 NMNCVWLIISEPGSRIHLIFNDFDVEPQ----FDFLAVKDDGISDITVLGTFSGNEVPSQ 663
Query: 859 TVASGSSMFLRFYSDASVQRKGFQAVHST 887
+SG + L F SD S +GF ++T
Sbjct: 664 LASSGHIVRLEFQSDHSTTGRGFNITYTT 692
Score = 143 bits (361), Expect = 7e-34
Identities = 175/708 (24%), Positives = 264/708 (37%), Gaps = 164/708 (23%)
Query: 442 WVEFRSSSNILG------KGFFAAYEATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRIT 495
W F+S +LG + AA CGG + G I+SP +P Y C W I
Sbjct: 4 WRRFQSLLLLLGLLVLCARLLTAAKGQNCGGLVQGPNGTIESPGFPHGYPNYANCTWIII 63
Query: 496 VSEGFHVGLTFQAFEIERHDSCAYDYLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLW 555
E + L+F F +E +D L V DG ++ L G++ P + S+ + L
Sbjct: 64 TGERNRIQLSFHTFALEED----FDILSVYDGQPQQGNLKVRLSGFQLPSSIVSTGSILT 119
Query: 556 MKFVSDGSINKAGFAANFFKEV---DECSWPDH--GGCEHRCVNTLGS-YKCACDPGYEL 609
+ F +D +++ GF A + EV C P G H +G + +C PGY L
Sbjct: 120 LWFTTDFAVSAQGFKALY--EVLPSHTCGNPGEILKGVLHGTRFNIGDKIRYSCLPGYIL 177
Query: 610 AADKKM--------------------CEVACGGFITKLNGTITSPGWPKEYPTNKNCVWQ 649
+ E ACGG + + +I+SP +P EY N +C W
Sbjct: 178 EGHAILTCIVSPGNGASWDFPAPFCRAEGACGGTLRGTSSSISSPHFPSEYENNADCTWT 237
Query: 650 VVAPAQYRISLQFEVFELEGNDVCKYDFVEVRSGLSPDAKLHGRFCGSETPEV------- 702
++A I+L F F+LE YDF+E+ +P L G S
Sbjct: 238 ILAEPGDTIALVFTDFQLEEG----YDFLEISGTEAPSIWLTGMNLPSPVISSKNWLRLH 293
Query: 703 ITSQSNNMRVEFKSDNTVSK------RGFRAHFFSD----------------KDECAK-- 738
TS SN+ R F + V K RG + D D C
Sbjct: 294 FTSDSNHRRKGFNAQFQVKKAIELKSRGVKMLPSKDGSHKNSVLSQGGVALVSDMCPDPG 353
Query: 739 --DNG------------GCQHECVNTF---GSYLCRCRN-----GYWLHENGHDCKEAGC 776
+NG Q C + + GS C+ W ++ C+ C
Sbjct: 354 IPENGRRAGSDFSRVGANVQFSCEDNYVLQGSKSITCQRVTETLAAW-SDHRPICRARTC 412
Query: 777 AHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRV-KLTFNEFEIEQHQECAYDHLE 835
+ G + SPN+P +Y C W I++T +V KL F EFE+E+ YD L
Sbjct: 413 GSNLRGPSGVITSPNYPVQYEDNAHCVWVITTTDPDKVIKLAFEEFELER----GYDTLT 468
Query: 836 MYDGPD--SLAPILGRFCGSKKPDPTVAS--------------GSSMFLRFYSD------ 873
+ D +L GS PD V+ GS F Y +
Sbjct: 469 VGDAGKVGDTRSVLYVLTGSSVPDLIVSMSNQMWLHLQSDDSIGSPGFKAVYQEIEKGGC 528
Query: 874 ------ASVQRKGFQAVHST----EC-------GGRLKAEVQTKELYSH----------- 905
A +R G +H EC G R+ Q + +
Sbjct: 529 GDPGIPAYGKRTGSSFLHGDTLTFECPAAFELVGERVITCQQNNQWSGNKPSCVFSCFFN 588
Query: 906 --AQFG---DNNYPSE----ARCDWVIVAEDGYGVELTFRTFEVEEEADCGYDYMEAYDG 956
A G NYP E C W+I++E G + L F F+VE + +D++ D
Sbjct: 589 FTASSGIILSPNYPEEYGNNMNCVWLIISEPGSRIHLIFNDFDVEPQ----FDFLAVKDD 644
Query: 957 YDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARYTS 1004
S LG F G+ ++ S+G + + F++D + +GF+ YT+
Sbjct: 645 GISDITVLGTFSGNEVPSQLASSGHIVRLEFQSDHSTTGRGFNITYTT 692
Score = 119 bits (298), Expect = 1e-26
Identities = 94/331 (28%), Positives = 143/331 (43%), Gaps = 39/331 (11%)
Query: 457 FAAYEATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDS 516
F +A CG ++ G I SP +PD+Y K+C+W ITV G V + F + E
Sbjct: 2140 FPRCDAPCGYNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTE---- 2195
Query: 517 CAYDYLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFK- 575
DY+ V DGP + S +G F G E SS+N++ +KF SD S N F NF
Sbjct: 2196 AVNDYIAVWDGPDQNSPQLGVFSGNTALETAYSSTNQVLLKFHSDFS-NGGFFVLNFHAF 2254
Query: 576 EVDECSWPDHGGCEHRCVN----TLGSY-KCACDPGYELAADKKM--------------- 615
++ +C P +G + K C PGY L +
Sbjct: 2255 QLKKCQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLP 2314
Query: 616 -CEVAC--GGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDV 672
CE C T +G I SPG+P Y ++ C W + Y I++ + F+ E
Sbjct: 2315 TCEAQCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEK--- 2371
Query: 673 CKYDFVEVRSGLSPDAKLHGRFCGSETPEV-ITSQSNNMRVEFKSDNTVSKRGFRAHFFS 731
++D +EV G S + L G+ T + TS+SN + + + +D+ SK+GF+ + +
Sbjct: 2372 -QFDALEVFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAA 2430
Query: 732 DKDECAK--DNGGCQHECVNTFGS---YLCR 757
NGG + GS Y C+
Sbjct: 2431 PYCSLTHPLKNGGILNRTAGAVGSKVHYFCK 2461
Score = 71.6 bits (174), Expect = 3e-12
Identities = 41/119 (34%), Positives = 62/119 (52%), Gaps = 8/119 (6%)
Query: 351 CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVE 410
CG +Q G +PGFP+GYP+Y++C W I +I L+F + L + +D +
Sbjct: 32 CGGLVQGPNGTIESPGFPHGYPNYANCTWIIITGERNRIQLSFHTFALEED----FDILS 87
Query: 411 VRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEA----TCG 465
V DG ++ L R G ++P +VST S L + F + + +GF A YE TCG
Sbjct: 88 VYDGQPQQGNLKVRLSGFQLPSSIVSTGSILTLWFTTDFAVSAQGFKALYEVLPSHTCG 146
Score = 67.8 bits (164), Expect = 5e-11
Identities = 35/107 (32%), Positives = 56/107 (52%), Gaps = 4/107 (3%)
Query: 350 ACGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYV 409
ACG L G +P +P YP C WR+ V P I L F S ++ S YD++
Sbjct: 1451 ACGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEPS----YDFL 1506
Query: 410 EVRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGF 456
+ +G +PL+G + G + PE + S+ + L++ FRS +++ GF
Sbjct: 1507 HIYEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGF 1553
Score = 67.4 bits (163), Expect = 7e-11
Identities = 39/112 (34%), Positives = 61/112 (54%), Gaps = 8/112 (7%)
Query: 350 ACGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYV 409
ACG TL+ T+ + S+P FP+ Y + + C W I PG+ I L FT L + YD++
Sbjct: 207 ACGGTLRGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEEG----YDFL 262
Query: 410 EVRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYE 461
E+ +AP + G +P P++S+ + L + F S SN KGF A ++
Sbjct: 263 EISG---TEAPSIW-LTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQ 310
Score = 64.7 bits (156), Expect = 4e-10
Identities = 37/112 (33%), Positives = 57/112 (50%), Gaps = 7/112 (6%)
Query: 347 KCPA-CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCW 405
+C A CG + G +PGFP+ YP C+W I+V PG + +NFT +
Sbjct: 2142 RCDAPCGYNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAVN--- 2198
Query: 406 YDYVEVRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFF 457
DY+ V DG + +P LG F G+ E S+ +++ ++F S+ GFF
Sbjct: 2199 -DYIAVWDGPDQNSPQLGVFSGNTALETAYSSTNQVLLKFH--SDFSNGGFF 2247
Score = 60.1 bits (144), Expect = 1e-08
Identities = 41/147 (27%), Positives = 69/147 (46%), Gaps = 6/147 (4%)
Query: 328 IGQRVRLSQGDIAQARKLYKCP-ACGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPG 386
+G+RV Q + + C +C ++G +P +P Y + +CVW I PG
Sbjct: 561 VGERVITCQQNNQWSGNKPSCVFSCFFNFTASSGIILSPNYPEEYGNNMNCVWLIISEPG 620
Query: 387 EKIVLNFTSMDLFKSRLCWYDYVEVRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFR 446
+I L F D+ +D++ V+D +LG F G+++P L S+ + +EF+
Sbjct: 621 SRIHLIFNDFDVEPQ----FDFLAVKDDGISDITVLGTFSGNEVPSQLASSGHIVRLEFQ 676
Query: 447 SSSNILGKGFFAAYEATCGGDMNKDAG 473
S + G+GF Y T G + D G
Sbjct: 677 SDHSTTGRGFNITY-TTFGQNECHDPG 702
Score = 59.7 bits (143), Expect = 1e-08
Identities = 29/96 (30%), Positives = 51/96 (53%), Gaps = 4/96 (4%)
Query: 913 YPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGYDYMEAYDGYDSSAPRLGRFCGSGP 972
Y C+W+I A+ G+ +++TF F+ E YD +E DG SS+P +G + G+
Sbjct: 779 YKDSLHCEWIIEAKPGHSIKITFDRFQTE----VNYDTLEVRDGPASSSPLIGEYHGTQA 834
Query: 973 LEEIYSAGDSLMIRFRTDDTINKKGFHARYTSTKFQ 1008
+ + S G+ + + F TD++ + GF Y S +
Sbjct: 835 PQFLISTGNFMYLLFTTDNSRSSIGFLIHYESVTLE 870
Score = 59.3 bits (142), Expect = 2e-08
Identities = 53/201 (26%), Positives = 84/201 (41%), Gaps = 16/201 (7%)
Query: 298 IMHYARNTFSRGVFLDTILPRQDDNGVRPTIGQRVRLSQGDIAQARKLYK--CPAC---- 351
I +Y G F DT++ + G + GD R+++ P+C
Sbjct: 1223 IPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNTLTCLSGD----RRVWDKPLPSCIAEC 1278
Query: 352 -GETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVE 410
G+ T+G +PG+P Y + HC W I PG+ I L+F D + +D ++
Sbjct: 1279 GGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTEMA----HDILK 1334
Query: 411 VRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEATCGGDMNK 470
V DG LL + G +PE + ST + L ++F S I GF + + N
Sbjct: 1335 VWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIAATCN- 1393
Query: 471 DAGQIQSPNYPDDYRPSKECV 491
D G Q+ D R + + V
Sbjct: 1394 DPGMPQNGTRYGDSREAGDTV 1414
Score = 54.7 bits (130), Expect = 4e-07
Identities = 34/118 (28%), Positives = 60/118 (50%), Gaps = 7/118 (5%)
Query: 345 LYKCPA-CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRL 403
L +C A CG +++ G +P FP+ Y + C+++I G+ I L S LF+
Sbjct: 1098 LPRCVAECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQLFEG-- 1155
Query: 404 CWYDYVEVRDGYWRKAPLLGRFCGDKIPEPLV-STDSRLWVEFRSSSNILGKGFFAAY 460
D ++V DG + LG F +++ ++ ST + LW+EF ++ + +GF Y
Sbjct: 1156 ---DTLKVYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQGFQLTY 1210
Score = 53.5 bits (127), Expect = 1e-06
Identities = 27/98 (27%), Positives = 48/98 (48%), Gaps = 4/98 (4%)
Query: 912 NYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGYDYMEAYDGYDSSAPRLGRFCGSG 971
+YP+ C W I GYG + F F E +D++E +G ++P +G+F G+
Sbjct: 1994 SYPNNLDCTWRISLPIGYGAHIQFLNFSTE----ANHDFLEIQNGPYHTSPMIGQFSGTD 2049
Query: 972 PLEEIYSAGDSLMIRFRTDDTINKKGFHARYTSTKFQD 1009
+ S +I F +D + N++GF Y + + Q+
Sbjct: 2050 LPAALLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQN 2087
Score = 50.4 bits (119), Expect = 8e-06
Identities = 36/118 (30%), Positives = 56/118 (47%), Gaps = 12/118 (10%)
Query: 889 CGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGY 948
CGG L+ T S F + Y + A C W I+AE G + L F F++EE GY
Sbjct: 208 CGGTLRG---TSSSISSPHF-PSEYENNADCTWTILAEPGDTIALVFTDFQLEE----GY 259
Query: 949 DYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARYTSTK 1006
D++E + AP + G + S+ + L + F +D +KGF+A++ K
Sbjct: 260 DFLEI---SGTEAPSIW-LTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQVKK 313
Score = 48.9 bits (115), Expect = 2e-05
Identities = 40/141 (28%), Positives = 64/141 (45%), Gaps = 15/141 (10%)
Query: 347 KCPACGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWY 406
+CPA E ++G +PG+P Y + C W I V P I + +D F+S +
Sbjct: 2319 QCPA-NEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITI---FVDTFQSEK-QF 2373
Query: 407 DYVEVRDGYWRKAPLLGRFCGDKIPEP-LVSTDSRLWVEFRSSSNILGKGFFAAYEATC- 464
D +EV DG ++PLL G+ + S ++L++ + + KGF Y A
Sbjct: 2374 DALEVFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAAPYC 2433
Query: 465 --------GGDMNKDAGQIQS 477
GG +N+ AG + S
Sbjct: 2434 SLTHPLKNGGILNRTAGAVGS 2454
Score = 42.0 bits (97), Expect = 0.003
Identities = 32/113 (28%), Positives = 54/113 (47%), Gaps = 6/113 (5%)
Query: 351 CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVE 410
CG + G +P +P+ Y + C++ I+V P E +V F F++ L D E
Sbjct: 1626 CGGQYTGSEGVVLSPNYPHNYTAGQICLYSITV-PKEFVV--FGQFAYFQTAL--NDLAE 1680
Query: 411 VRDGYWRKAPLLGRFCGDKIPEPL-VSTDSRLWVEFRSSSNILGKGFFAAYEA 462
+ DG +A LL G E L ++T +++ + F + S +GF Y+A
Sbjct: 1681 LFDGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGFHFVYQA 1733
>gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo sapiens]
Length = 3667
Score = 213 bits (543), Expect = 6e-55
Identities = 179/657 (27%), Positives = 276/657 (42%), Gaps = 134/657 (20%)
Query: 343 RKLYKCPACGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIV-LNFTSMDLFKS 401
R + K CG LQ +G F++P FP Y S + CVW I+ K++ +NF DL
Sbjct: 500 RPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDL--- 556
Query: 402 RLCWYDYVEVRDGYWRKAP--LLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAA 459
YD + + DG P +L G +P+ +VS S++W+ ++ ++ GF
Sbjct: 557 -EIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVN 615
Query: 460 Y----EATCG-------------GDMNKDA------------------------------ 472
Y + +CG G N+D
Sbjct: 616 YKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIP 675
Query: 473 --------------GQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCA 518
G + SP+YP+ Y + C+W I G + L+F F++E
Sbjct: 676 ICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQ---- 731
Query: 519 YDYLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGF--AANFFKE 576
+D+L V+DG + ES ++G F G E P + S+S+ L ++F +D S++ GF N F
Sbjct: 732 FDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGH 791
Query: 577 VDECSWPDHG--------------------GCEHRCVNTLGSYKCAC---DPGYELAADK 613
+EC PD G CE + T G+ C D +
Sbjct: 792 -NEC--PDPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLI 848
Query: 614 KMCEVACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVC 673
C CGG + +G I SPGWP Y + NC W + A + I + FE F+ E N
Sbjct: 849 PKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELN--- 905
Query: 674 KYDFVEVRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHF---- 729
YD +EV G + + L G + G++ P+ + S SN + + F +DN+ S GF+ H+
Sbjct: 906 -YDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVT 964
Query: 730 ---FSDKDECAKDNGGCQHECVNTFGSYLCRCRNGYWL-HENGHDCK------------E 773
+S D +G + + C +GY L HE C+ +
Sbjct: 965 VNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCD 1024
Query: 774 AGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDH 833
A C + GT+ SP +P+ YP+ CTW + T G V+ F+ F +E H +D+
Sbjct: 1025 ALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDH----HDY 1080
Query: 834 LEMYDGPDSLAPILGRFCGSKKPDPTVASG----SSMFLRFYSDASVQRKGFQAVHS 886
L + + P L R GS P PT+ +G LRF SD S+ +GF S
Sbjct: 1081 LLITENGSFTQP-LARLTGSDLP-PTINAGLYGNFRAQLRFISDFSISYEGFNITFS 1135
Score = 207 bits (526), Expect = 5e-53
Identities = 172/648 (26%), Positives = 281/648 (43%), Gaps = 126/648 (19%)
Query: 463 TCGGDMNKDAGQIQSPNYPDDYRPSKECVWRIT-VSEGFHVGLTFQAFEIERHDSCAYDY 521
TCG ++ +G SPN+P Y + +CVW IT V+ + + F+ F++E YD
Sbjct: 507 TCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLE----IGYDT 562
Query: 522 LEVRDGPT--EESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDE 579
L + DG + ++ G P+ + S S+++W+ +D S+ GF N+ KE+++
Sbjct: 563 LTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNY-KEIEK 621
Query: 580 CSWPDHG----------GCEHRCV---------NTLGSYKCACDPGYELAADKKMCEVAC 620
S D G G +R V +G C + +A+ +C C
Sbjct: 622 ESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPC 681
Query: 621 GGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVEV 680
T GT+ SP +P+ Y N NC+W +++ RI L F F+LE ++DF+ V
Sbjct: 682 LSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLES----QFDFLAV 737
Query: 681 RSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFS-DKDEC--- 736
+ G SP++ + G F G+E P +TS S+ +R+EF++D+++S RGF + + +EC
Sbjct: 738 KDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDP 797
Query: 737 -----AKDNGG-----------CQHECVNTFGSYLCRC--RNGYWLHENGHDCKEAGCAH 778
A+ G C+ + T G+ C +G + A C
Sbjct: 798 GIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGG 857
Query: 779 KISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMYD 838
S+ G + SP WP Y C W I + GH +K+TF F+ E + YD LE++D
Sbjct: 858 HFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELN----YDVLEVHD 913
Query: 839 GPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQ---------------- 882
GP+ L+P+LG + G++ P +S + ++L F +D S GF+
Sbjct: 914 GPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDP 973
Query: 883 --AVH----------------STECGGRLKAE----VQTKELYSHAQ-------FGDNNY 913
VH S + G RL E + +SH GD
Sbjct: 974 GIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCGGDVRG 1033
Query: 914 PS--------------EARCDWVIVAEDGYGVELTFRTFEVEEEADCGYDYMEAYDGYDS 959
PS C W + G GV+ F TF +E+ +DY+ +
Sbjct: 1034 PSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDH----HDYLLITENGSF 1089
Query: 960 SAPRLGRFCGSGPLEEIYSAG----DSLMIRFRTDDTINKKGFHARYT 1003
+ P L R GS L +AG +RF +D +I+ +GF+ ++
Sbjct: 1090 TQP-LARLTGS-DLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFS 1135
Score = 194 bits (494), Expect = 3e-49
Identities = 176/644 (27%), Positives = 261/644 (40%), Gaps = 124/644 (19%)
Query: 351 CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVE 410
CG L ++G +P FP+ YP C W I+V I L F S + + YD++
Sbjct: 1548 CGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN----YDFLY 1603
Query: 411 VRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEA----TC-- 464
+ DG +PL+G F K+PE + S+ + + + FRS ++ GF Y+A +C
Sbjct: 1604 IYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFD 1663
Query: 465 -GGDMNK-----------------DAGQIQSPN------YPDDYRPS---------KECV 491
G MN DAG + DD RP C
Sbjct: 1664 PGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCG 1723
Query: 492 WRITVSEGFHVGLTFQAFEIERHDSCAY----------------------DYLEVRDGPT 529
R T SEG + + H +C Y D +EV DGPT
Sbjct: 1724 SRSTGSEGTVLSPNYPKNYSVGH-NCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPT 1782
Query: 530 EESALIGHFCGYEKPEDVK-SSSNRLWMKFVSDGSINKAGFAANFFKEV------DECSW 582
++S+L+ G E + SS N++ ++F S G I GF +F + +CS
Sbjct: 1783 QQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGF--HFVYQAVPRTSSTQCSS 1840
Query: 583 PDHGGCEHRCVNTL---GSYKCACDPGYELAADKKM------------------CEVACG 621
R N S C+PGY L + C V CG
Sbjct: 1841 VPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCIVPCG 1900
Query: 622 GFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVEVR 681
G +TK GTI SPG+P+ Y N NCVW++ P I +Q F E N +D ++
Sbjct: 1901 GILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN----WDSLDFY 1956
Query: 682 SGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFS-DKDECAK-- 738
G +A G + G+ P ++ S SNN+ + F+SD +VS GF + + D C +
Sbjct: 1957 DGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQ 2016
Query: 739 -DNGGCQHECVNTFGSYLC-RCRNGYWLHENGH-DCKE--------------AGCAHKIS 781
+ G + G + +C GY L + H C A C +S
Sbjct: 2017 TPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAMS 2076
Query: 782 SVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMYDGPD 841
G + SP +P YPS +CTW I+ G V L F F E +D+LE+ G
Sbjct: 2077 DFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFS----TETIHDYLEVRSGSS 2132
Query: 842 SLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQAVH 885
+ ++GR G + P ++ L F+SD S ++GF V+
Sbjct: 2133 ETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVY 2176
Score = 187 bits (474), Expect = 6e-47
Identities = 137/474 (28%), Positives = 213/474 (44%), Gaps = 73/474 (15%)
Query: 462 ATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDY 521
A CGG++ +G I SPN+P Y S++C W ITV+ + + L F +F IE + YD+
Sbjct: 1546 APCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN----YDF 1601
Query: 522 LEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECS 581
L + DGP S LIG F + PE ++SSSN + + F SDGS++ GF + ++ E
Sbjct: 1602 LYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESC 1661
Query: 582 WPDHG--------GCEHRCVNTLGSYKCACDPGYELAADKKM------------------ 615
+ D G G +++ +T+ Y CD GY L +
Sbjct: 1662 F-DPGNIMNGTRLGMDYKLGSTVTYY---CDAGYVLQGYSTLTCIMGDDGRPGWNRALPS 1717
Query: 616 CEVACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKY 675
C CG T GT+ SP +PK Y NCV+ + P ++ + QF F+ +DV
Sbjct: 1718 CHAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDV--- 1774
Query: 676 DFVEVRSGLSPDAKLHGRFCGSETPEVI-TSQSNNMRVEFKSDNTVSKRGFRAHFF---- 730
VEV G + + L GS + E + S N + + F S ++ +GF HF
Sbjct: 1775 --VEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGF--HFVYQAV 1830
Query: 731 --SDKDECAK-DNGGCQHECVNTF---GSYLCRCRNGYWLHEN-GHDCKE---------- 773
+ +C+ N F S L C GY LH + C+
Sbjct: 1831 PRTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWND 1890
Query: 774 ------AGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQ 827
C ++ +GT+ SP +P+ Y + C W I+ G +++ F E +
Sbjct: 1891 SLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN- 1949
Query: 828 ECAYDHLEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGF 881
+D L+ YDG D+ AP LG + G+ P ++ ++++L F SD SV GF
Sbjct: 1950 ---WDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGF 2000
Score = 187 bits (474), Expect = 6e-47
Identities = 144/469 (30%), Positives = 218/469 (46%), Gaps = 64/469 (13%)
Query: 462 ATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDY 521
A CGG M+ +G I SP +P +Y S +C W I + GF V L F F E +DY
Sbjct: 2069 AQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTET----IHDY 2124
Query: 522 LEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECS 581
LEVR G +E S +IG G + P + S+++ + F SD S NK GF ++ S
Sbjct: 2125 LEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHI-VYQAYQLQS 2183
Query: 582 WPDHGGCEHRCVN----TLG-SYKCACDPGYELAADKKM----------------CEVAC 620
PD + V T+G + C PGY L + + CE C
Sbjct: 2184 CPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALC 2243
Query: 621 GGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVEV 680
GG IT +NGTI SPG+P EYP ++C W V P I + F V + E YDF+ V
Sbjct: 2244 GGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEP----IYDFITV 2299
Query: 681 RSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGF--------------- 725
G ++ G+F G+ E + S SN + ++F SD T S GF
Sbjct: 2300 WDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTS--GFFVLSYHAYQLRVCQP 2357
Query: 726 -----RAHFFSDKDECAKDNGGCQHECVNTF---GSYLCRCRNGYWLHENGHD--CKEAG 775
A ++ DE + +++C+ F G+ + CR G L +G C+
Sbjct: 2358 PPPVPNAEILTEDDE-FEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQVLC 2416
Query: 776 CAHKIS-SVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHL 834
A+++ G + SP +PD YP+ + C W+IS G+ + + F+ E+ +D L
Sbjct: 2417 PANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKE----FDVL 2472
Query: 835 EMYDGPDSLAPILGRFCGSKKPDPTVAS-GSSMFLRFYSDASVQRKGFQ 882
++YDGP+ +P+L G + S G +FL++ +D +KGF+
Sbjct: 2473 QVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFR 2521
Score = 184 bits (467), Expect = 4e-46
Identities = 137/465 (29%), Positives = 209/465 (44%), Gaps = 59/465 (12%)
Query: 462 ATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDY 521
A CG + G + SPNYP +Y + EC++ I V G + ++ + F + + D
Sbjct: 1199 AECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGD-----V 1253
Query: 522 LEVRDGPTEESALIGHFCGYE-KPEDVKSSSNRLWMKFVSDGSINKAGFAANFFK-EVDE 579
L++ DG + + L+G F G + + S+SN+LW++F SD GF + E+
Sbjct: 1254 LKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSH 1313
Query: 580 CSWPDHGGCEHRCVNTLGSYKCA-----CDPGYELAADKKM----------------CEV 618
C P ++ ++ G + + C+PGY L + C
Sbjct: 1314 CEDPGIPQFGYK-ISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIA 1372
Query: 619 ACGG-FITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDF 677
CGG F + +G I SPG+P Y N C+W + +SLQF F+ E + +D
Sbjct: 1373 ECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEAS----HDI 1428
Query: 678 VEVRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECA 737
+ V G + L GS PE I S N + ++F +D +SK GF F S
Sbjct: 1429 LRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATAC 1488
Query: 738 KDNGGCQHECVNTFG-----SYLCRCRNGYWLH-ENGHDCKE---------------AGC 776
+D G + N G + + +C GY L E C + A C
Sbjct: 1489 RDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPC 1548
Query: 777 AHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEM 836
++ G + SPN+P YP R+C W I+ A + + L F F IE + YD L +
Sbjct: 1549 GGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN----YDFLYI 1604
Query: 837 YDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGF 881
YDGPDS +P++G F SK P+ +S ++M L F SD SV GF
Sbjct: 1605 YDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGF 1649
Score = 176 bits (446), Expect = 1e-43
Identities = 138/482 (28%), Positives = 212/482 (43%), Gaps = 60/482 (12%)
Query: 451 ILGKGFFAAYEATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFE 510
++ G A CGG + +G I SP +P Y+ S C W I G + +TF+ F+
Sbjct: 842 VMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQ 901
Query: 511 IERHDSCAYDYLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGF- 569
E + YD LEV DGP S L+G + G + P+ + SSSN +++ F +D S + GF
Sbjct: 902 TELN----YDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFK 957
Query: 570 ------AANFFKEVDECSWPDHGGCEHRCVNTLGSYKCACDPGYELAADKKM-------- 615
N + +D P HG + + +CD GY L+ ++ +
Sbjct: 958 IHYESVTVNTYSCLDP-GIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWW 1016
Query: 616 ------CEVACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEG 669
C+ CGG + +GTI SPG+P+ YP + NC W V + F F LE
Sbjct: 1017 SHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLED 1076
Query: 670 NDVCKYDFVEVRSGLSPDAKLHGRFCGSETPEVITS-QSNNMRVE--FKSDNTVSKRGFR 726
+ +D++ + S L R GS+ P I + N R + F SD ++S GF
Sbjct: 1077 H----HDYLLITENGSFTQPL-ARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFN 1131
Query: 727 AHFFSDKDECAKDNGGCQHECVNTFG-----SYLCRCRNGYWLHENGH-DCKEAG----- 775
F E +D G Q+ F + C +GY L C G
Sbjct: 1132 ITFSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWS 1191
Query: 776 ---------CAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQH 826
C ++ EG L SPN+P Y + EC ++I AG + ++ F + Q
Sbjct: 1192 APLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQG 1251
Query: 827 QECAYDHLEMYDGPDSLAPILGRFCGSKKPDPTVASGSS-MFLRFYSDASVQRKGFQAVH 885
D L++YDG D +LG F G+ T++S S+ ++L F SD +GFQ V+
Sbjct: 1252 -----DVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVY 1306
Query: 886 ST 887
++
Sbjct: 1307 TS 1308
Score = 159 bits (401), Expect = 2e-38
Identities = 156/621 (25%), Positives = 261/621 (42%), Gaps = 115/621 (18%)
Query: 350 ACGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYV 409
ACG T++ ++G S+P FPN Y + + C W I PG+ I L FT + + YDY+
Sbjct: 200 ACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEK----YDYL 255
Query: 410 EVRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEA------- 462
E+ P G IP P++S + L + F + SN +GF A Y+
Sbjct: 256 EIEGS----EPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQGSSTLTHT 311
Query: 463 TCGGDMNKD----AGQIQSPNYPDD-----------YRPSKECVWRITVSEGFHVGLTFQ 507
T G++ + G I + P D +R S+E ++T +
Sbjct: 312 TSTGELEEHNRTTTGAIAVASTPADVTVSSVTAVTIHRLSEEQRVQVTSLRNSGLDPNTS 371
Query: 508 AFEIERHDSCAYDYLEVRDGP--------TEESALIGHFCGYEKPEDVKSSSNRLW---- 555
+ H + D R P T+E A++ H +K D KS +L+
Sbjct: 372 KDGLSPHPA---DTQSTRRRPRHAEQIERTKELAVVTH--RVKKAIDFKSRGFKLFPGKD 426
Query: 556 ----MKFVSDGSINKAGFAANFFKEVDECSWPDHGGCEHRCVNTLGSYKCACDPGYELAA 611
+++G I A +N + E P++G + + + +CD Y L
Sbjct: 427 NSNKFSILNEGGIKTA---SNLCPDPGE---PENGKRIGSDFSLGSTVQFSCDEDYVLQG 480
Query: 612 DKKM------------------CEV-ACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVA 652
K + C+V CG + +GT TSP +P +Y +N CVW + A
Sbjct: 481 AKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITA 540
Query: 653 PAQYR-ISLQFEVFELEGNDVCKYDFVEVRSG--LSPDAKLHGRFCGSETPEVITSQSNN 709
+ I + FE F+LE YD + + G + + GS P++I S S+
Sbjct: 541 VNTNKVIQINFEEFDLE----IGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQ 596
Query: 710 MRVEFKSDNTVSKRGFRAHFFS-DKDECA---------KDNGGCQHECVNTFGSYLCRCR 759
M + ++D +V GF+ ++ +K+ C ++ G + V F C+
Sbjct: 597 MWLHLQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRF-----ECQ 651
Query: 760 NGYWL-HENGHDCKEAG------------CAHKISSVEGTLASPNWPDKYPSRRECTWNI 806
G+ L E C+E C ++ GT+ SP++P+ Y + C W I
Sbjct: 652 FGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTI 711
Query: 807 SSTAGHRVKLTFNEFEIEQHQECAYDHLEMYDGPDSLAPILGRFCGSKKPDPTVASGSSM 866
S G R+ L+FN+F++E +D L + DG +PILG F G++ P ++ +
Sbjct: 712 ISDPGSRIHLSFNDFDLESQ----FDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSHIL 767
Query: 867 FLRFYSDASVQRKGFQAVHST 887
L F +D S+ +GF ++T
Sbjct: 768 RLEFQADHSMSGRGFNITYNT 788
Score = 143 bits (360), Expect = 9e-34
Identities = 160/648 (24%), Positives = 249/648 (38%), Gaps = 124/648 (19%)
Query: 461 EATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYD 520
+A CGGD+ +G I SP YP+ Y S C W + V+ G V F F +E H +D
Sbjct: 1024 DALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDH----HD 1079
Query: 521 YLEVRDGPTEESALIGHFCGYEKPEDVKS---SSNRLWMKFVSDGSINKAGFAANFFK-E 576
YL + + + L G + P + + + R ++F+SD SI+ GF F +
Sbjct: 1080 YLLITENGSFTQPL-ARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYN 1138
Query: 577 VDECSWPDHGGCEHRCVNTLG---SYKCACDPGYEL----------------AADKKMCE 617
++ C P R G + +C GY L +A C
Sbjct: 1139 LEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCV 1198
Query: 618 VACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDF 677
CG T G + SP +P Y N C++ + A I++ F L DV K
Sbjct: 1199 AECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLK--- 1255
Query: 678 VEVRSGLSPDAKLHGRFCGSETPEV-ITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDEC 736
+ G L G F G+ + ++S SN + +EF SD + GF+ + S +
Sbjct: 1256 --IYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSH 1313
Query: 737 AKDNG---------------------GCQHECVNTFGSYLCRCRNG---YWLHENGHDCK 772
+D G GC + GS L +C G W +
Sbjct: 1314 CEDPGIPQFGYKISDQGHFAGSTIIYGC-NPGYTLHGSSLLKCMTGERRAWDYPLPSCIA 1372
Query: 773 EAGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYD 832
E G K S G + SP +P Y + C W I G+ V L F F+ E ++D
Sbjct: 1373 ECGGRFKGES-SGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFD----TEASHD 1427
Query: 833 HLEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQAVHS----TE 888
L ++DGP +L GS P+ ++ + + ++F +D + + GF S T
Sbjct: 1428 ILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATA 1487
Query: 889 C-------------GGRLKA-----------EVQTKELYSHAQFGDNNY---PSE----A 917
C GR E+Q +E + Q +N Y PS A
Sbjct: 1488 CRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQV-ENRYFWQPSPPVCIA 1546
Query: 918 RCDWVIVAEDGYGVELTFRTFEVEEEADCGY------DYMEA-----------YD----- 955
C + G+ + F DC + DY+ + YD
Sbjct: 1547 PCGGNLTGSSGFILSPNF-PHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIY 1605
Query: 956 -GYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARY 1002
G DS++P +G F S E I S+ +++ + FR+D +++ GFH Y
Sbjct: 1606 DGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEY 1653
Score = 113 bits (282), Expect = 1e-24
Identities = 84/314 (26%), Positives = 138/314 (43%), Gaps = 46/314 (14%)
Query: 620 CGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVE 679
CGG + LNGTI SPG+P YP NC W ++A + RI + F+ F LE +YD++
Sbjct: 25 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEE----EYDYLS 80
Query: 680 VRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECAKD 739
+ G R G P +TS + + SD VS GF+ ++ + +
Sbjct: 81 LYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKV-YYEELQSSSCG 139
Query: 740 NGGCQHECVNTFGSYL-------CRCRNGYWLHENGHD--------------------CK 772
N G + V +G+ C GY L +GH C+
Sbjct: 140 NPGVPPKGV-LYGTRFDVGDKIRYSCVTGYIL--DGHPQLTCIANSVNTASWDFPVPICR 196
Query: 773 -EAGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAY 831
E C + G ++SP++P++Y + +CTW I + G + L F +F++E+ Y
Sbjct: 197 AEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEE----KY 252
Query: 832 DHLEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQAVHSTECGG 891
D+LE+ + P G P P +++ + + L F +D++ + +GF A + +
Sbjct: 253 DYLEI----EGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPY--QGSS 306
Query: 892 RLKAEVQTKELYSH 905
L T EL H
Sbjct: 307 TLTHTTSTGELEEH 320
Score = 111 bits (277), Expect = 4e-24
Identities = 81/292 (27%), Positives = 123/292 (42%), Gaps = 38/292 (13%)
Query: 463 TCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDYL 522
TCGG + G I+SP +P Y C W I E + + FQ+F +E YDYL
Sbjct: 24 TCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEE----YDYL 79
Query: 523 EVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECSW 582
+ DG + G+ P V S+ + ++ SD +++ GF +++E+ S
Sbjct: 80 SLYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKV-YYEELQSSSC 138
Query: 583 -----PDHGGCEHRCVNTLGSYKCACDPGYELAADKKM--------------------CE 617
P G + + +C GY L ++ E
Sbjct: 139 GNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAE 198
Query: 618 VACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDF 677
ACGG + +G I+SP +P EY N +C W +VA ISL F F++E KYD+
Sbjct: 199 DACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEE----KYDY 254
Query: 678 VEVRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHF 729
+E+ P L G P I S N +R+ F +D+ RGF A +
Sbjct: 255 LEIEGSEPPTIWL----SGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPY 302
Score = 108 bits (270), Expect = 3e-23
Identities = 83/299 (27%), Positives = 134/299 (44%), Gaps = 40/299 (13%)
Query: 461 EATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYD 520
EA CGG++ G I SP YPD+Y ++C W + V G + + F + E YD
Sbjct: 2240 EALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEP----IYD 2295
Query: 521 YLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGF----------- 569
++ V DGP + S IG F G E V S+SN++ +KF SD +GF
Sbjct: 2296 FITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSD--FTTSGFFVLSYHAYQLR 2353
Query: 570 ---------AANFFKEVDECSWPDHGGCEHRCV---NTLGSYKCACDPGYELAAD--KKM 615
A E DE D ++C+ +G+ C G L D +
Sbjct: 2354 VCQPPPPVPNAEILTEDDEFEIGDI--IRYQCLPGFTLVGNAILTCRLGERLQMDGAPPV 2411
Query: 616 CEVACGGFITKLN--GTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVC 673
C+V C +L+ G I SPG+P YP + C W + Y I++ E F+ E
Sbjct: 2412 CQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEK---- 2467
Query: 674 KYDFVEVRSGLSPDAKLHGRFCGSETPEV-ITSQSNNMRVEFKSDNTVSKRGFRAHFFS 731
++D ++V G + + + G + ITS + + +++ +D+ +K+GFR + +
Sbjct: 2468 EFDVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIA 2526
Score = 87.4 bits (215), Expect = 6e-17
Identities = 72/294 (24%), Positives = 121/294 (41%), Gaps = 68/294 (23%)
Query: 771 CKEAGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRV-KLTFNEFEIEQHQEC 829
CK C + GT SPN+P +Y S +C W I++ ++V ++ F EF++E
Sbjct: 503 CKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLE----I 558
Query: 830 AYDHLEMYDGPDSLAP--ILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQA---- 883
YD L + DG + P +L GS PD V+ S M+L +D SV GF+
Sbjct: 559 GYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKE 618
Query: 884 VHSTECG--GRLKAEVQTKELYSH-------AQFG------------DNN---------- 912
+ CG G ++ + +S+ QFG +NN
Sbjct: 619 IEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICI 678
Query: 913 ----------------------YPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGYDY 950
Y + C W I+++ G + L+F F++E + +D+
Sbjct: 679 FPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQ----FDF 734
Query: 951 MEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARYTS 1004
+ DG +P LG F G+ + S L + F+ D +++ +GF+ Y +
Sbjct: 735 LAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNT 788
Score = 70.1 bits (170), Expect = 1e-11
Identities = 37/114 (32%), Positives = 61/114 (53%), Gaps = 7/114 (6%)
Query: 345 LYKCPA-CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRL 403
L +C A CG + G +PG+P+ YP++ C W + V PG I +NFT +
Sbjct: 2236 LPRCEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPI-- 2293
Query: 404 CWYDYVEVRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFF 457
YD++ V DG + +P +G+F G+ E + ST +++ ++F S+ GFF
Sbjct: 2294 --YDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFH--SDFTTSGFF 2343
Score = 67.8 bits (164), Expect = 5e-11
Identities = 38/112 (33%), Positives = 55/112 (49%), Gaps = 4/112 (3%)
Query: 351 CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVE 410
CG + D +G +PGFP YPS C W I++ G + L F + S +DY+E
Sbjct: 2071 CGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNF----STETIHDYLE 2126
Query: 411 VRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEA 462
VR G + ++GR G +IP L ST + F S + +GF Y+A
Sbjct: 2127 VRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQA 2178
Score = 64.7 bits (156), Expect = 4e-10
Identities = 38/119 (31%), Positives = 55/119 (46%), Gaps = 8/119 (6%)
Query: 351 CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVE 410
CG TL+ G +PGFP GYP+ ++C W I +I + F S L + YDY+
Sbjct: 25 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEE----YDYLS 80
Query: 411 VRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYE----ATCG 465
+ DG+ R G +P P+ ST S + S + GF YE ++CG
Sbjct: 81 LYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCG 139
Score = 63.9 bits (154), Expect = 7e-10
Identities = 42/145 (28%), Positives = 61/145 (42%), Gaps = 8/145 (5%)
Query: 461 EATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYD 520
E CGG M +G I SP++P++Y + +C W I G + L F F++E YD
Sbjct: 198 EDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEE----KYD 253
Query: 521 YLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDEC 580
YLE+ L G P + S+ N L + FV+D + GF+A +
Sbjct: 254 YLEIEGSEPPTIWL----SGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQGSSTLT 309
Query: 581 SWPDHGGCEHRCVNTLGSYKCACDP 605
G E T G+ A P
Sbjct: 310 HTTSTGELEEHNRTTTGAIAVASTP 334
Score = 63.2 bits (152), Expect = 1e-09
Identities = 40/130 (30%), Positives = 66/130 (50%), Gaps = 5/130 (3%)
Query: 334 LSQGDIAQARKLYKCPA-CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLN 392
L G + + + KC A CG +G +PG+P Y +C W I PG I +
Sbjct: 837 LMDGKVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKIT 896
Query: 393 FTSMDLFKSRLCWYDYVEVRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNIL 452
F + F++ L YD +EV DG +PLLG + G ++P+ L S+ + +++ F + ++
Sbjct: 897 F---ERFQTELN-YDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRS 952
Query: 453 GKGFFAAYEA 462
GF YE+
Sbjct: 953 NNGFKIHYES 962
Score = 62.0 bits (149), Expect = 3e-09
Identities = 32/104 (30%), Positives = 56/104 (53%), Gaps = 8/104 (7%)
Query: 889 CGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGY 948
CGG + A T +YS + YP+ C W++ G G+ + F + E Y
Sbjct: 2243 CGGNITAMNGT--IYSPGY--PDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPI----Y 2294
Query: 949 DYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDT 992
D++ +DG D ++P++G+F G+ LE +YS + ++I+F +D T
Sbjct: 2295 DFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFT 2338
Score = 61.2 bits (147), Expect = 5e-09
Identities = 35/116 (30%), Positives = 59/116 (50%), Gaps = 8/116 (6%)
Query: 889 CGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGY 948
CGG L T + + DNN C W I +G G+++ +F E +
Sbjct: 1899 CGGILTKRKGTILSPGYPEPYDNNL----NCVWKITVPEGAGIQVQVVSFATEHN----W 1950
Query: 949 DYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARYTS 1004
D ++ YDG D++APRLG + G+ + S ++L + F++D +++ GFH YT+
Sbjct: 1951 DSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTA 2006
Score = 56.6 bits (135), Expect = 1e-07
Identities = 31/97 (31%), Positives = 45/97 (46%), Gaps = 4/97 (4%)
Query: 912 NYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGYDYMEAYDGYDSSAPRLGRFCGSG 971
NYPS C W I G+GV L F F E +DY+E G ++ +GR G
Sbjct: 2090 NYPSSLDCTWTINLPIGFGVHLQFVNFSTETI----HDYLEVRSGSSETSTVIGRLSGPQ 2145
Query: 972 PLEEIYSAGDSLMIRFRTDDTINKKGFHARYTSTKFQ 1008
++S + F +D + NK+GFH Y + + Q
Sbjct: 2146 IPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQ 2182
Score = 56.2 bits (134), Expect = 2e-07
Identities = 35/114 (30%), Positives = 51/114 (44%), Gaps = 8/114 (7%)
Query: 889 CGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGY 948
CGG LK T E YP+ A C WVI+AE+ +++ F++F +EEE Y
Sbjct: 25 CGGTLKGLNGTIESPGFPY----GYPNGANCTWVIIAEERNRIQIVFQSFALEEE----Y 76
Query: 949 DYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARY 1002
DY+ YDG+ R G + S +R +D ++ GF Y
Sbjct: 77 DYLSLYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYY 130
Score = 54.7 bits (130), Expect = 4e-07
Identities = 38/118 (32%), Positives = 56/118 (47%), Gaps = 7/118 (5%)
Query: 888 ECGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCG 947
ECGGR K E + L F Y + RC W+I + G V L F F+ E
Sbjct: 1373 ECGGRFKGESSGRILSPGYPFP---YDNNLRCMWMIEVDPGNIVSLQFLAFDTE----AS 1425
Query: 948 YDYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARYTST 1005
+D + +DG + L GS E I+S + + I+F TD I+K GF +++S+
Sbjct: 1426 HDILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSS 1483
Score = 51.6 bits (122), Expect = 4e-06
Identities = 40/122 (32%), Positives = 60/122 (49%), Gaps = 7/122 (5%)
Query: 343 RKLYKCPA-CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKS 401
R L C A CG + G +P +P Y +CV+ I+V P E +V F F++
Sbjct: 1713 RALPSCHAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAV-PKEFVV--FGQFVFFQT 1769
Query: 402 RLCWYDYVEVRDGYWRKAPLLGRFCGDKIPEPL-VSTDSRLWVEFRSSSNILGKGFFAAY 460
L +D VEV DG +++ LL G E L +S+ +++ + F S I KGF Y
Sbjct: 1770 SL--HDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVY 1827
Query: 461 EA 462
+A
Sbjct: 1828 QA 1829
Score = 51.2 bits (121), Expect = 5e-06
Identities = 34/118 (28%), Positives = 57/118 (48%), Gaps = 7/118 (5%)
Query: 345 LYKCPA-CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRL 403
L +C A CG + + G +P +P Y + C++ I V G+ I ++ + L +
Sbjct: 1194 LPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQG-- 1251
Query: 404 CWYDYVEVRDGYWRKAPLLGRFCGDKIPE-PLVSTDSRLWVEFRSSSNILGKGFFAAY 460
D +++ DG + LLG F G + L ST ++LW+EF S + +GF Y
Sbjct: 1252 ---DVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVY 1306
Score = 51.2 bits (121), Expect = 5e-06
Identities = 29/93 (31%), Positives = 45/93 (48%), Gaps = 5/93 (5%)
Query: 911 NNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGYDYMEAYDGYDSSAPRLGRFCGS 970
++YP+ C W I E GY + + F+ E+E +D ++ YDG + +P L G
Sbjct: 2436 DSYPNLQMCAWSISVEKGYNITMFVEFFQTEKE----FDVLQVYDGPNIQSPVLISLSGD 2491
Query: 971 -GPLEEIYSAGDSLMIRFRTDDTINKKGFHARY 1002
I S G + +++ D NKKGF RY
Sbjct: 2492 YSSAFNITSNGHEVFLQWSADHGNNKKGFRIRY 2524
Score = 49.3 bits (116), Expect = 2e-05
Identities = 37/114 (32%), Positives = 51/114 (44%), Gaps = 12/114 (10%)
Query: 889 CGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGY 948
CGG ++ + + S F N Y + A C W IVAE G + L F F++EE+ Y
Sbjct: 201 CGGTMRG---SSGIISSPSF-PNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEK----Y 252
Query: 949 DYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARY 1002
DY+E + S P G I S + L + F TD +GF A Y
Sbjct: 253 DYLE----IEGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPY 302
Score = 47.8 bits (112), Expect = 5e-05
Identities = 34/116 (29%), Positives = 53/116 (45%), Gaps = 6/116 (5%)
Query: 348 CPACGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYD 407
CPA E D+TG +PG+P+ YP+ C W ISV G I + K +D
Sbjct: 2416 CPA-NELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKE----FD 2470
Query: 408 YVEVRDGYWRKAPLLGRFCGD-KIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEA 462
++V DG ++P+L GD + S +++++ + KGF Y A
Sbjct: 2471 VLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIA 2526
Score = 44.3 bits (103), Expect = 6e-04
Identities = 27/94 (28%), Positives = 44/94 (46%), Gaps = 6/94 (6%)
Query: 912 NYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGYDYMEAYDGYDSSAPRLGRFCGSG 971
NY + C + I + G G+ ++ RTF + + D ++ YDG D + LG F G+
Sbjct: 1220 NYENNHECIYSIQVQAGKGINISARTFHLAQG-----DVLKIYDGKDKTTHLLGAFTGAS 1274
Query: 972 PLE-EIYSAGDSLMIRFRTDDTINKKGFHARYTS 1004
+ S + L + F +D +GF YTS
Sbjct: 1275 MRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTS 1308
Score = 34.7 bits (78), Expect = 0.47
Identities = 20/56 (35%), Positives = 28/56 (50%), Gaps = 1/56 (1%)
Query: 948 YDYMEAYDGYDSSAPRLGRFCGSGPLEEI-YSAGDSLMIRFRTDDTINKKGFHARY 1002
+D +E YDG + L GS E + S+G+ + IRF + I KGFH Y
Sbjct: 1772 HDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVY 1827
>gi|205277354 CUB and Sushi multiple domains 3 isoform 3 [Homo
sapiens]
Length = 3538
Score = 213 bits (543), Expect = 6e-55
Identities = 179/657 (27%), Positives = 276/657 (42%), Gaps = 134/657 (20%)
Query: 343 RKLYKCPACGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIV-LNFTSMDLFKS 401
R + K CG LQ +G F++P FP Y S + CVW I+ K++ +NF DL
Sbjct: 436 RPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDL--- 492
Query: 402 RLCWYDYVEVRDGYWRKAP--LLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAA 459
YD + + DG P +L G +P+ +VS S++W+ ++ ++ GF
Sbjct: 493 -EIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVN 551
Query: 460 Y----EATCG-------------GDMNKDA------------------------------ 472
Y + +CG G N+D
Sbjct: 552 YKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIP 611
Query: 473 --------------GQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCA 518
G + SP+YP+ Y + C+W I G + L+F F++E
Sbjct: 612 ICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQ---- 667
Query: 519 YDYLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGF--AANFFKE 576
+D+L V+DG + ES ++G F G E P + S+S+ L ++F +D S++ GF N F
Sbjct: 668 FDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGH 727
Query: 577 VDECSWPDHG--------------------GCEHRCVNTLGSYKCAC---DPGYELAADK 613
+EC PD G CE + T G+ C D +
Sbjct: 728 -NEC--PDPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLI 784
Query: 614 KMCEVACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVC 673
C CGG + +G I SPGWP Y + NC W + A + I + FE F+ E N
Sbjct: 785 PKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELN--- 841
Query: 674 KYDFVEVRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHF---- 729
YD +EV G + + L G + G++ P+ + S SN + + F +DN+ S GF+ H+
Sbjct: 842 -YDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVT 900
Query: 730 ---FSDKDECAKDNGGCQHECVNTFGSYLCRCRNGYWL-HENGHDCK------------E 773
+S D +G + + C +GY L HE C+ +
Sbjct: 901 VNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCD 960
Query: 774 AGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDH 833
A C + GT+ SP +P+ YP+ CTW + T G V+ F+ F +E H +D+
Sbjct: 961 ALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDH----HDY 1016
Query: 834 LEMYDGPDSLAPILGRFCGSKKPDPTVASG----SSMFLRFYSDASVQRKGFQAVHS 886
L + + P L R GS P PT+ +G LRF SD S+ +GF S
Sbjct: 1017 LLITENGSFTQP-LARLTGSDLP-PTINAGLYGNFRAQLRFISDFSISYEGFNITFS 1071
Score = 207 bits (526), Expect = 5e-53
Identities = 172/648 (26%), Positives = 281/648 (43%), Gaps = 126/648 (19%)
Query: 463 TCGGDMNKDAGQIQSPNYPDDYRPSKECVWRIT-VSEGFHVGLTFQAFEIERHDSCAYDY 521
TCG ++ +G SPN+P Y + +CVW IT V+ + + F+ F++E YD
Sbjct: 443 TCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLE----IGYDT 498
Query: 522 LEVRDGPT--EESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDE 579
L + DG + ++ G P+ + S S+++W+ +D S+ GF N+ KE+++
Sbjct: 499 LTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNY-KEIEK 557
Query: 580 CSWPDHG----------GCEHRCV---------NTLGSYKCACDPGYELAADKKMCEVAC 620
S D G G +R V +G C + +A+ +C C
Sbjct: 558 ESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPC 617
Query: 621 GGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVEV 680
T GT+ SP +P+ Y N NC+W +++ RI L F F+LE ++DF+ V
Sbjct: 618 LSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLES----QFDFLAV 673
Query: 681 RSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFS-DKDEC--- 736
+ G SP++ + G F G+E P +TS S+ +R+EF++D+++S RGF + + +EC
Sbjct: 674 KDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDP 733
Query: 737 -----AKDNGG-----------CQHECVNTFGSYLCRC--RNGYWLHENGHDCKEAGCAH 778
A+ G C+ + T G+ C +G + A C
Sbjct: 734 GIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGG 793
Query: 779 KISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMYD 838
S+ G + SP WP Y C W I + GH +K+TF F+ E + YD LE++D
Sbjct: 794 HFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELN----YDVLEVHD 849
Query: 839 GPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQ---------------- 882
GP+ L+P+LG + G++ P +S + ++L F +D S GF+
Sbjct: 850 GPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDP 909
Query: 883 --AVH----------------STECGGRLKAE----VQTKELYSHAQ-------FGDNNY 913
VH S + G RL E + +SH GD
Sbjct: 910 GIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCGGDVRG 969
Query: 914 PS--------------EARCDWVIVAEDGYGVELTFRTFEVEEEADCGYDYMEAYDGYDS 959
PS C W + G GV+ F TF +E+ +DY+ +
Sbjct: 970 PSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDH----HDYLLITENGSF 1025
Query: 960 SAPRLGRFCGSGPLEEIYSAG----DSLMIRFRTDDTINKKGFHARYT 1003
+ P L R GS L +AG +RF +D +I+ +GF+ ++
Sbjct: 1026 TQP-LARLTGS-DLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFS 1071
Score = 194 bits (494), Expect = 3e-49
Identities = 176/644 (27%), Positives = 261/644 (40%), Gaps = 124/644 (19%)
Query: 351 CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVE 410
CG L ++G +P FP+ YP C W I+V I L F S + + YD++
Sbjct: 1484 CGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN----YDFLY 1539
Query: 411 VRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEA----TC-- 464
+ DG +PL+G F K+PE + S+ + + + FRS ++ GF Y+A +C
Sbjct: 1540 IYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFD 1599
Query: 465 -GGDMNK-----------------DAGQIQSPN------YPDDYRPS---------KECV 491
G MN DAG + DD RP C
Sbjct: 1600 PGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCG 1659
Query: 492 WRITVSEGFHVGLTFQAFEIERHDSCAY----------------------DYLEVRDGPT 529
R T SEG + + H +C Y D +EV DGPT
Sbjct: 1660 SRSTGSEGTVLSPNYPKNYSVGH-NCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPT 1718
Query: 530 EESALIGHFCGYEKPEDVK-SSSNRLWMKFVSDGSINKAGFAANFFKEV------DECSW 582
++S+L+ G E + SS N++ ++F S G I GF +F + +CS
Sbjct: 1719 QQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGF--HFVYQAVPRTSSTQCSS 1776
Query: 583 PDHGGCEHRCVNTL---GSYKCACDPGYELAADKKM------------------CEVACG 621
R N S C+PGY L + C V CG
Sbjct: 1777 VPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCIVPCG 1836
Query: 622 GFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVEVR 681
G +TK GTI SPG+P+ Y N NCVW++ P I +Q F E N +D ++
Sbjct: 1837 GILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN----WDSLDFY 1892
Query: 682 SGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFS-DKDECAK-- 738
G +A G + G+ P ++ S SNN+ + F+SD +VS GF + + D C +
Sbjct: 1893 DGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQ 1952
Query: 739 -DNGGCQHECVNTFGSYLC-RCRNGYWLHENGH-DCKE--------------AGCAHKIS 781
+ G + G + +C GY L + H C A C +S
Sbjct: 1953 TPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAMS 2012
Query: 782 SVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMYDGPD 841
G + SP +P YPS +CTW I+ G V L F F E +D+LE+ G
Sbjct: 2013 DFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFS----TETIHDYLEVRSGSS 2068
Query: 842 SLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQAVH 885
+ ++GR G + P ++ L F+SD S ++GF V+
Sbjct: 2069 ETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVY 2112
Score = 187 bits (474), Expect = 6e-47
Identities = 137/474 (28%), Positives = 213/474 (44%), Gaps = 73/474 (15%)
Query: 462 ATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDY 521
A CGG++ +G I SPN+P Y S++C W ITV+ + + L F +F IE + YD+
Sbjct: 1482 APCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN----YDF 1537
Query: 522 LEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECS 581
L + DGP S LIG F + PE ++SSSN + + F SDGS++ GF + ++ E
Sbjct: 1538 LYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESC 1597
Query: 582 WPDHG--------GCEHRCVNTLGSYKCACDPGYELAADKKM------------------ 615
+ D G G +++ +T+ Y CD GY L +
Sbjct: 1598 F-DPGNIMNGTRLGMDYKLGSTVTYY---CDAGYVLQGYSTLTCIMGDDGRPGWNRALPS 1653
Query: 616 CEVACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKY 675
C CG T GT+ SP +PK Y NCV+ + P ++ + QF F+ +DV
Sbjct: 1654 CHAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDV--- 1710
Query: 676 DFVEVRSGLSPDAKLHGRFCGSETPEVI-TSQSNNMRVEFKSDNTVSKRGFRAHFF---- 730
VEV G + + L GS + E + S N + + F S ++ +GF HF
Sbjct: 1711 --VEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGF--HFVYQAV 1766
Query: 731 --SDKDECAK-DNGGCQHECVNTF---GSYLCRCRNGYWLHEN-GHDCKE---------- 773
+ +C+ N F S L C GY LH + C+
Sbjct: 1767 PRTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWND 1826
Query: 774 ------AGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQ 827
C ++ +GT+ SP +P+ Y + C W I+ G +++ F E +
Sbjct: 1827 SLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN- 1885
Query: 828 ECAYDHLEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGF 881
+D L+ YDG D+ AP LG + G+ P ++ ++++L F SD SV GF
Sbjct: 1886 ---WDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGF 1936
Score = 187 bits (474), Expect = 6e-47
Identities = 144/469 (30%), Positives = 218/469 (46%), Gaps = 64/469 (13%)
Query: 462 ATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDY 521
A CGG M+ +G I SP +P +Y S +C W I + GF V L F F E +DY
Sbjct: 2005 AQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTET----IHDY 2060
Query: 522 LEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECS 581
LEVR G +E S +IG G + P + S+++ + F SD S NK GF ++ S
Sbjct: 2061 LEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHI-VYQAYQLQS 2119
Query: 582 WPDHGGCEHRCVN----TLG-SYKCACDPGYELAADKKM----------------CEVAC 620
PD + V T+G + C PGY L + + CE C
Sbjct: 2120 CPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALC 2179
Query: 621 GGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVEV 680
GG IT +NGTI SPG+P EYP ++C W V P I + F V + E YDF+ V
Sbjct: 2180 GGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEP----IYDFITV 2235
Query: 681 RSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGF--------------- 725
G ++ G+F G+ E + S SN + ++F SD T S GF
Sbjct: 2236 WDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTS--GFFVLSYHAYQLRVCQP 2293
Query: 726 -----RAHFFSDKDECAKDNGGCQHECVNTF---GSYLCRCRNGYWLHENGHD--CKEAG 775
A ++ DE + +++C+ F G+ + CR G L +G C+
Sbjct: 2294 PPPVPNAEILTEDDE-FEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQVLC 2352
Query: 776 CAHKIS-SVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHL 834
A+++ G + SP +PD YP+ + C W+IS G+ + + F+ E+ +D L
Sbjct: 2353 PANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKE----FDVL 2408
Query: 835 EMYDGPDSLAPILGRFCGSKKPDPTVAS-GSSMFLRFYSDASVQRKGFQ 882
++YDGP+ +P+L G + S G +FL++ +D +KGF+
Sbjct: 2409 QVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFR 2457
Score = 184 bits (467), Expect = 4e-46
Identities = 137/465 (29%), Positives = 209/465 (44%), Gaps = 59/465 (12%)
Query: 462 ATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDY 521
A CG + G + SPNYP +Y + EC++ I V G + ++ + F + + D
Sbjct: 1135 AECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGD-----V 1189
Query: 522 LEVRDGPTEESALIGHFCGYE-KPEDVKSSSNRLWMKFVSDGSINKAGFAANFFK-EVDE 579
L++ DG + + L+G F G + + S+SN+LW++F SD GF + E+
Sbjct: 1190 LKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSH 1249
Query: 580 CSWPDHGGCEHRCVNTLGSYKCA-----CDPGYELAADKKM----------------CEV 618
C P ++ ++ G + + C+PGY L + C
Sbjct: 1250 CEDPGIPQFGYK-ISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIA 1308
Query: 619 ACGG-FITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDF 677
CGG F + +G I SPG+P Y N C+W + +SLQF F+ E + +D
Sbjct: 1309 ECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEAS----HDI 1364
Query: 678 VEVRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECA 737
+ V G + L GS PE I S N + ++F +D +SK GF F S
Sbjct: 1365 LRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATAC 1424
Query: 738 KDNGGCQHECVNTFG-----SYLCRCRNGYWLH-ENGHDCKE---------------AGC 776
+D G + N G + + +C GY L E C + A C
Sbjct: 1425 RDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPC 1484
Query: 777 AHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEM 836
++ G + SPN+P YP R+C W I+ A + + L F F IE + YD L +
Sbjct: 1485 GGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN----YDFLYI 1540
Query: 837 YDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGF 881
YDGPDS +P++G F SK P+ +S ++M L F SD SV GF
Sbjct: 1541 YDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGF 1585
Score = 176 bits (446), Expect = 1e-43
Identities = 138/482 (28%), Positives = 212/482 (43%), Gaps = 60/482 (12%)
Query: 451 ILGKGFFAAYEATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFE 510
++ G A CGG + +G I SP +P Y+ S C W I G + +TF+ F+
Sbjct: 778 VMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQ 837
Query: 511 IERHDSCAYDYLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGF- 569
E + YD LEV DGP S L+G + G + P+ + SSSN +++ F +D S + GF
Sbjct: 838 TELN----YDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFK 893
Query: 570 ------AANFFKEVDECSWPDHGGCEHRCVNTLGSYKCACDPGYELAADKKM-------- 615
N + +D P HG + + +CD GY L+ ++ +
Sbjct: 894 IHYESVTVNTYSCLDP-GIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWW 952
Query: 616 ------CEVACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEG 669
C+ CGG + +GTI SPG+P+ YP + NC W V + F F LE
Sbjct: 953 SHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLED 1012
Query: 670 NDVCKYDFVEVRSGLSPDAKLHGRFCGSETPEVITS-QSNNMRVE--FKSDNTVSKRGFR 726
+ +D++ + S L R GS+ P I + N R + F SD ++S GF
Sbjct: 1013 H----HDYLLITENGSFTQPL-ARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFN 1067
Query: 727 AHFFSDKDECAKDNGGCQHECVNTFG-----SYLCRCRNGYWLHENGH-DCKEAG----- 775
F E +D G Q+ F + C +GY L C G
Sbjct: 1068 ITFSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWS 1127
Query: 776 ---------CAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQH 826
C ++ EG L SPN+P Y + EC ++I AG + ++ F + Q
Sbjct: 1128 APLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQG 1187
Query: 827 QECAYDHLEMYDGPDSLAPILGRFCGSKKPDPTVASGSS-MFLRFYSDASVQRKGFQAVH 885
D L++YDG D +LG F G+ T++S S+ ++L F SD +GFQ V+
Sbjct: 1188 -----DVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVY 1242
Query: 886 ST 887
++
Sbjct: 1243 TS 1244
Score = 163 bits (413), Expect = 7e-40
Identities = 163/684 (23%), Positives = 259/684 (37%), Gaps = 165/684 (24%)
Query: 463 TCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDYL 522
TCGG + G I+SP +P Y C W I E + + FQ+F +E YDYL
Sbjct: 64 TCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEE----YDYL 119
Query: 523 EVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECSW 582
+ DG + G+ P V S+ + ++ SD +++ GF +++E+ S
Sbjct: 120 SLYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKV-YYEELQSSSC 178
Query: 583 -----PDHGGCEHRCVNTLGSYKCACDPGYELAADKKM--------------------CE 617
P G + + +C GY L ++ E
Sbjct: 179 GNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAE 238
Query: 618 VACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDF 677
ACGG + +G I+SP +P EY N +C W +VA ISL F F++E KYD+
Sbjct: 239 DACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEE----KYDY 294
Query: 678 VEVRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNT-----------------V 720
+E+ P L G P I S N +R+ F +D+
Sbjct: 295 LEIEGSEPPTIWLSGM----NIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAIDF 350
Query: 721 SKRGFRAHFFSDKDECAK----DNGGC-----------------------------QHEC 747
RGF+ F KD K + GG Q C
Sbjct: 351 KSRGFK--LFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTVQFSC 408
Query: 748 VNTF---GSYLCRCRNGYWLHENGHD----CKEAGCAHKISSVEGTLASPNWPDKYPSRR 800
+ G+ C+ + D CK C + GT SPN+P +Y S
Sbjct: 409 DEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNA 468
Query: 801 ECTWNISSTAGHRV-KLTFNEFEIEQHQECAYDHLEMYDGPDSLAP--ILGRFCGSKKPD 857
+C W I++ ++V ++ F EF++E YD L + DG + P +L GS PD
Sbjct: 469 QCVWVITAVNTNKVIQINFEEFDLE----IGYDTLTIGDGGEVGDPRTVLQVLTGSFVPD 524
Query: 858 PTVASGSSMFLRFYSDASVQRKGFQA----VHSTECG--GRLKAEVQTKELYSH------ 905
V+ S M+L +D SV GF+ + CG G ++ + +S+
Sbjct: 525 LIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRF 584
Query: 906 -AQFG------------DNN--------------------------------YPSEARCD 920
QFG +NN Y + C
Sbjct: 585 ECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCI 644
Query: 921 WVIVAEDGYGVELTFRTFEVEEEADCGYDYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAG 980
W I+++ G + L+F F++E + +D++ DG +P LG F G+ + S
Sbjct: 645 WTIISDPGSRIHLSFNDFDLESQ----FDFLAVKDGDSPESPILGTFTGAEVPSHLTSNS 700
Query: 981 DSLMIRFRTDDTINKKGFHARYTS 1004
L + F+ D +++ +GF+ Y +
Sbjct: 701 HILRLEFQADHSMSGRGFNITYNT 724
Score = 155 bits (391), Expect = 2e-37
Identities = 133/508 (26%), Positives = 218/508 (42%), Gaps = 102/508 (20%)
Query: 461 EATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYD 520
E CGG M +G I SP++P++Y + +C W I G + L F F++E YD
Sbjct: 238 EDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEK----YD 293
Query: 521 YLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFF--KEVD 578
YLE+ L G P + S+ N L + FV+D + GF+A + K +D
Sbjct: 294 YLEIEGSEPPTIWL----SGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAID 349
Query: 579 ----------------ECSWPDHGGCE---HRCVN--------------TLGS-YKCACD 604
+ S + GG + + C + +LGS + +CD
Sbjct: 350 FKSRGFKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTVQFSCD 409
Query: 605 PGYELAADKKM------------------CEV-ACGGFITKLNGTITSPGWPKEYPTNKN 645
Y L K + C+V CG + +GT TSP +P +Y +N
Sbjct: 410 EDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQ 469
Query: 646 CVWQVVAPAQYR-ISLQFEVFELEGNDVCKYDFVEVRSG--LSPDAKLHGRFCGSETPEV 702
CVW + A + I + FE F+LE YD + + G + + GS P++
Sbjct: 470 CVWVITAVNTNKVIQINFEEFDLE----IGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDL 525
Query: 703 ITSQSNNMRVEFKSDNTVSKRGFRAHFFS-DKDECA---------KDNGGCQHECVNTFG 752
I S S+ M + ++D +V GF+ ++ +K+ C ++ G + V F
Sbjct: 526 IVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRF- 584
Query: 753 SYLCRCRNGYWL-HENGHDCKEAG------------CAHKISSVEGTLASPNWPDKYPSR 799
C+ G+ L E C+E C ++ GT+ SP++P+ Y +
Sbjct: 585 ----ECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNN 640
Query: 800 RECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMYDGPDSLAPILGRFCGSKKPDPT 859
C W I S G R+ L+FN+F++E +D L + DG +PILG F G++ P
Sbjct: 641 LNCIWTIISDPGSRIHLSFNDFDLESQ----FDFLAVKDGDSPESPILGTFTGAEVPSHL 696
Query: 860 VASGSSMFLRFYSDASVQRKGFQAVHST 887
++ + L F +D S+ +GF ++T
Sbjct: 697 TSNSHILRLEFQADHSMSGRGFNITYNT 724
Score = 143 bits (360), Expect = 9e-34
Identities = 160/648 (24%), Positives = 249/648 (38%), Gaps = 124/648 (19%)
Query: 461 EATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYD 520
+A CGGD+ +G I SP YP+ Y S C W + V+ G V F F +E H +D
Sbjct: 960 DALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDH----HD 1015
Query: 521 YLEVRDGPTEESALIGHFCGYEKPEDVKS---SSNRLWMKFVSDGSINKAGFAANFFK-E 576
YL + + + L G + P + + + R ++F+SD SI+ GF F +
Sbjct: 1016 YLLITENGSFTQPL-ARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYN 1074
Query: 577 VDECSWPDHGGCEHRCVNTLG---SYKCACDPGYEL----------------AADKKMCE 617
++ C P R G + +C GY L +A C
Sbjct: 1075 LEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCV 1134
Query: 618 VACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDF 677
CG T G + SP +P Y N C++ + A I++ F L DV K
Sbjct: 1135 AECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLK--- 1191
Query: 678 VEVRSGLSPDAKLHGRFCGSETPEV-ITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDEC 736
+ G L G F G+ + ++S SN + +EF SD + GF+ + S +
Sbjct: 1192 --IYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSH 1249
Query: 737 AKDNG---------------------GCQHECVNTFGSYLCRCRNG---YWLHENGHDCK 772
+D G GC + GS L +C G W +
Sbjct: 1250 CEDPGIPQFGYKISDQGHFAGSTIIYGC-NPGYTLHGSSLLKCMTGERRAWDYPLPSCIA 1308
Query: 773 EAGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYD 832
E G K S G + SP +P Y + C W I G+ V L F F+ E ++D
Sbjct: 1309 ECGGRFKGES-SGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFD----TEASHD 1363
Query: 833 HLEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQAVHS----TE 888
L ++DGP +L GS P+ ++ + + ++F +D + + GF S T
Sbjct: 1364 ILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATA 1423
Query: 889 C-------------GGRLKA-----------EVQTKELYSHAQFGDNNY---PSE----A 917
C GR E+Q +E + Q +N Y PS A
Sbjct: 1424 CRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQV-ENRYFWQPSPPVCIA 1482
Query: 918 RCDWVIVAEDGYGVELTFRTFEVEEEADCGY------DYMEA-----------YD----- 955
C + G+ + F DC + DY+ + YD
Sbjct: 1483 PCGGNLTGSSGFILSPNF-PHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIY 1541
Query: 956 -GYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARY 1002
G DS++P +G F S E I S+ +++ + FR+D +++ GFH Y
Sbjct: 1542 DGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEY 1589
Score = 108 bits (270), Expect = 3e-23
Identities = 83/299 (27%), Positives = 134/299 (44%), Gaps = 40/299 (13%)
Query: 461 EATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYD 520
EA CGG++ G I SP YPD+Y ++C W + V G + + F + E YD
Sbjct: 2176 EALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEP----IYD 2231
Query: 521 YLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGF----------- 569
++ V DGP + S IG F G E V S+SN++ +KF SD +GF
Sbjct: 2232 FITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSD--FTTSGFFVLSYHAYQLR 2289
Query: 570 ---------AANFFKEVDECSWPDHGGCEHRCV---NTLGSYKCACDPGYELAAD--KKM 615
A E DE D ++C+ +G+ C G L D +
Sbjct: 2290 VCQPPPPVPNAEILTEDDEFEIGDI--IRYQCLPGFTLVGNAILTCRLGERLQMDGAPPV 2347
Query: 616 CEVACGGFITKLN--GTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVC 673
C+V C +L+ G I SPG+P YP + C W + Y I++ E F+ E
Sbjct: 2348 CQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEK---- 2403
Query: 674 KYDFVEVRSGLSPDAKLHGRFCGSETPEV-ITSQSNNMRVEFKSDNTVSKRGFRAHFFS 731
++D ++V G + + + G + ITS + + +++ +D+ +K+GFR + +
Sbjct: 2404 EFDVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIA 2462
Score = 70.1 bits (170), Expect = 1e-11
Identities = 37/114 (32%), Positives = 61/114 (53%), Gaps = 7/114 (6%)
Query: 345 LYKCPA-CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRL 403
L +C A CG + G +PG+P+ YP++ C W + V PG I +NFT +
Sbjct: 2172 LPRCEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPI-- 2229
Query: 404 CWYDYVEVRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFF 457
YD++ V DG + +P +G+F G+ E + ST +++ ++F S+ GFF
Sbjct: 2230 --YDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFH--SDFTTSGFF 2279
Score = 67.8 bits (164), Expect = 5e-11
Identities = 38/112 (33%), Positives = 55/112 (49%), Gaps = 4/112 (3%)
Query: 351 CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVE 410
CG + D +G +PGFP YPS C W I++ G + L F + S +DY+E
Sbjct: 2007 CGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNF----STETIHDYLE 2062
Query: 411 VRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEA 462
VR G + ++GR G +IP L ST + F S + +GF Y+A
Sbjct: 2063 VRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQA 2114
Score = 66.2 bits (160), Expect = 1e-10
Identities = 38/112 (33%), Positives = 57/112 (50%), Gaps = 8/112 (7%)
Query: 350 ACGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYV 409
ACG T++ ++G S+P FPN Y + + C W I PG+ I L FT + + YDY+
Sbjct: 240 ACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEK----YDYL 295
Query: 410 EVRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYE 461
E+ P G IP P++S + L + F + SN +GF A Y+
Sbjct: 296 EIEG----SEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQ 343
Score = 64.7 bits (156), Expect = 4e-10
Identities = 38/119 (31%), Positives = 55/119 (46%), Gaps = 8/119 (6%)
Query: 351 CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVE 410
CG TL+ G +PGFP GYP+ ++C W I +I + F S L + YDY+
Sbjct: 65 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEE----YDYLS 120
Query: 411 VRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYE----ATCG 465
+ DG+ R G +P P+ ST S + S + GF YE ++CG
Sbjct: 121 LYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCG 179
Score = 63.2 bits (152), Expect = 1e-09
Identities = 40/130 (30%), Positives = 66/130 (50%), Gaps = 5/130 (3%)
Query: 334 LSQGDIAQARKLYKCPA-CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLN 392
L G + + + KC A CG +G +PG+P Y +C W I PG I +
Sbjct: 773 LMDGKVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKIT 832
Query: 393 FTSMDLFKSRLCWYDYVEVRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNIL 452
F + F++ L YD +EV DG +PLLG + G ++P+ L S+ + +++ F + ++
Sbjct: 833 F---ERFQTELN-YDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRS 888
Query: 453 GKGFFAAYEA 462
GF YE+
Sbjct: 889 NNGFKIHYES 898
Score = 62.0 bits (149), Expect = 3e-09
Identities = 32/104 (30%), Positives = 56/104 (53%), Gaps = 8/104 (7%)
Query: 889 CGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGY 948
CGG + A T +YS + YP+ C W++ G G+ + F + E Y
Sbjct: 2179 CGGNITAMNGT--IYSPGY--PDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPI----Y 2230
Query: 949 DYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDT 992
D++ +DG D ++P++G+F G+ LE +YS + ++I+F +D T
Sbjct: 2231 DFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFT 2274
Score = 61.2 bits (147), Expect = 5e-09
Identities = 35/116 (30%), Positives = 59/116 (50%), Gaps = 8/116 (6%)
Query: 889 CGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGY 948
CGG L T + + DNN C W I +G G+++ +F E +
Sbjct: 1835 CGGILTKRKGTILSPGYPEPYDNNL----NCVWKITVPEGAGIQVQVVSFATEHN----W 1886
Query: 949 DYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARYTS 1004
D ++ YDG D++APRLG + G+ + S ++L + F++D +++ GFH YT+
Sbjct: 1887 DSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTA 1942
Score = 56.6 bits (135), Expect = 1e-07
Identities = 31/97 (31%), Positives = 45/97 (46%), Gaps = 4/97 (4%)
Query: 912 NYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGYDYMEAYDGYDSSAPRLGRFCGSG 971
NYPS C W I G+GV L F F E +DY+E G ++ +GR G
Sbjct: 2026 NYPSSLDCTWTINLPIGFGVHLQFVNFSTETI----HDYLEVRSGSSETSTVIGRLSGPQ 2081
Query: 972 PLEEIYSAGDSLMIRFRTDDTINKKGFHARYTSTKFQ 1008
++S + F +D + NK+GFH Y + + Q
Sbjct: 2082 IPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQ 2118
Score = 54.7 bits (130), Expect = 4e-07
Identities = 38/118 (32%), Positives = 56/118 (47%), Gaps = 7/118 (5%)
Query: 888 ECGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCG 947
ECGGR K E + L F Y + RC W+I + G V L F F+ E
Sbjct: 1309 ECGGRFKGESSGRILSPGYPFP---YDNNLRCMWMIEVDPGNIVSLQFLAFDTE----AS 1361
Query: 948 YDYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARYTST 1005
+D + +DG + L GS E I+S + + I+F TD I+K GF +++S+
Sbjct: 1362 HDILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSS 1419
Score = 51.6 bits (122), Expect = 4e-06
Identities = 40/122 (32%), Positives = 60/122 (49%), Gaps = 7/122 (5%)
Query: 343 RKLYKCPA-CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKS 401
R L C A CG + G +P +P Y +CV+ I+V P E +V F F++
Sbjct: 1649 RALPSCHAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAV-PKEFVV--FGQFVFFQT 1705
Query: 402 RLCWYDYVEVRDGYWRKAPLLGRFCGDKIPEPL-VSTDSRLWVEFRSSSNILGKGFFAAY 460
L +D VEV DG +++ LL G E L +S+ +++ + F S I KGF Y
Sbjct: 1706 SL--HDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVY 1763
Query: 461 EA 462
+A
Sbjct: 1764 QA 1765
Score = 51.2 bits (121), Expect = 5e-06
Identities = 34/118 (28%), Positives = 57/118 (48%), Gaps = 7/118 (5%)
Query: 345 LYKCPA-CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRL 403
L +C A CG + + G +P +P Y + C++ I V G+ I ++ + L +
Sbjct: 1130 LPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQG-- 1187
Query: 404 CWYDYVEVRDGYWRKAPLLGRFCGDKIPE-PLVSTDSRLWVEFRSSSNILGKGFFAAY 460
D +++ DG + LLG F G + L ST ++LW+EF S + +GF Y
Sbjct: 1188 ---DVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVY 1242
Score = 51.2 bits (121), Expect = 5e-06
Identities = 29/93 (31%), Positives = 45/93 (48%), Gaps = 5/93 (5%)
Query: 911 NNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGYDYMEAYDGYDSSAPRLGRFCGS 970
++YP+ C W I E GY + + F+ E+E +D ++ YDG + +P L G
Sbjct: 2372 DSYPNLQMCAWSISVEKGYNITMFVEFFQTEKE----FDVLQVYDGPNIQSPVLISLSGD 2427
Query: 971 -GPLEEIYSAGDSLMIRFRTDDTINKKGFHARY 1002
I S G + +++ D NKKGF RY
Sbjct: 2428 YSSAFNITSNGHEVFLQWSADHGNNKKGFRIRY 2460
Score = 50.1 bits (118), Expect = 1e-05
Identities = 39/121 (32%), Positives = 53/121 (43%), Gaps = 12/121 (9%)
Query: 889 CGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGY 948
CGG ++ + + S F N Y + A C W IVAE G + L F F++EE+ Y
Sbjct: 241 CGGTMRG---SSGIISSPSF-PNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEK----Y 292
Query: 949 DYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARYTSTKFQ 1008
DY+E + S P G I S + L + F TD +GF A Y K
Sbjct: 293 DYLE----IEGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAI 348
Query: 1009 D 1009
D
Sbjct: 349 D 349
Score = 47.8 bits (112), Expect = 5e-05
Identities = 34/116 (29%), Positives = 53/116 (45%), Gaps = 6/116 (5%)
Query: 348 CPACGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYD 407
CPA E D+TG +PG+P+ YP+ C W ISV G I + K +D
Sbjct: 2352 CPA-NELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKE----FD 2406
Query: 408 YVEVRDGYWRKAPLLGRFCGD-KIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEA 462
++V DG ++P+L GD + S +++++ + KGF Y A
Sbjct: 2407 VLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIA 2462
Score = 44.3 bits (103), Expect = 6e-04
Identities = 27/94 (28%), Positives = 44/94 (46%), Gaps = 6/94 (6%)
Query: 912 NYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGYDYMEAYDGYDSSAPRLGRFCGSG 971
NY + C + I + G G+ ++ RTF + + D ++ YDG D + LG F G+
Sbjct: 1156 NYENNHECIYSIQVQAGKGINISARTFHLAQG-----DVLKIYDGKDKTTHLLGAFTGAS 1210
Query: 972 PLE-EIYSAGDSLMIRFRTDDTINKKGFHARYTS 1004
+ S + L + F +D +GF YTS
Sbjct: 1211 MRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTS 1244
Score = 34.7 bits (78), Expect = 0.47
Identities = 20/56 (35%), Positives = 28/56 (50%), Gaps = 1/56 (1%)
Query: 948 YDYMEAYDGYDSSAPRLGRFCGSGPLEEI-YSAGDSLMIRFRTDDTINKKGFHARY 1002
+D +E YDG + L GS E + S+G+ + IRF + I KGFH Y
Sbjct: 1708 HDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVY 1763
>gi|38045888 CUB and Sushi multiple domains 3 isoform 1 [Homo sapiens]
Length = 3707
Score = 213 bits (543), Expect = 6e-55
Identities = 179/657 (27%), Positives = 276/657 (42%), Gaps = 134/657 (20%)
Query: 343 RKLYKCPACGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIV-LNFTSMDLFKS 401
R + K CG LQ +G F++P FP Y S + CVW I+ K++ +NF DL
Sbjct: 540 RPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDL--- 596
Query: 402 RLCWYDYVEVRDGYWRKAP--LLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAA 459
YD + + DG P +L G +P+ +VS S++W+ ++ ++ GF
Sbjct: 597 -EIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVN 655
Query: 460 Y----EATCG-------------GDMNKDA------------------------------ 472
Y + +CG G N+D
Sbjct: 656 YKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIP 715
Query: 473 --------------GQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCA 518
G + SP+YP+ Y + C+W I G + L+F F++E
Sbjct: 716 ICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQ---- 771
Query: 519 YDYLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGF--AANFFKE 576
+D+L V+DG + ES ++G F G E P + S+S+ L ++F +D S++ GF N F
Sbjct: 772 FDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGH 831
Query: 577 VDECSWPDHG--------------------GCEHRCVNTLGSYKCAC---DPGYELAADK 613
+EC PD G CE + T G+ C D +
Sbjct: 832 -NEC--PDPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLI 888
Query: 614 KMCEVACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVC 673
C CGG + +G I SPGWP Y + NC W + A + I + FE F+ E N
Sbjct: 889 PKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELN--- 945
Query: 674 KYDFVEVRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHF---- 729
YD +EV G + + L G + G++ P+ + S SN + + F +DN+ S GF+ H+
Sbjct: 946 -YDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVT 1004
Query: 730 ---FSDKDECAKDNGGCQHECVNTFGSYLCRCRNGYWL-HENGHDCK------------E 773
+S D +G + + C +GY L HE C+ +
Sbjct: 1005 VNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCD 1064
Query: 774 AGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDH 833
A C + GT+ SP +P+ YP+ CTW + T G V+ F+ F +E H +D+
Sbjct: 1065 ALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDH----HDY 1120
Query: 834 LEMYDGPDSLAPILGRFCGSKKPDPTVASG----SSMFLRFYSDASVQRKGFQAVHS 886
L + + P L R GS P PT+ +G LRF SD S+ +GF S
Sbjct: 1121 LLITENGSFTQP-LARLTGSDLP-PTINAGLYGNFRAQLRFISDFSISYEGFNITFS 1175
Score = 207 bits (526), Expect = 5e-53
Identities = 172/648 (26%), Positives = 281/648 (43%), Gaps = 126/648 (19%)
Query: 463 TCGGDMNKDAGQIQSPNYPDDYRPSKECVWRIT-VSEGFHVGLTFQAFEIERHDSCAYDY 521
TCG ++ +G SPN+P Y + +CVW IT V+ + + F+ F++E YD
Sbjct: 547 TCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLE----IGYDT 602
Query: 522 LEVRDGPT--EESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDE 579
L + DG + ++ G P+ + S S+++W+ +D S+ GF N+ KE+++
Sbjct: 603 LTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNY-KEIEK 661
Query: 580 CSWPDHG----------GCEHRCV---------NTLGSYKCACDPGYELAADKKMCEVAC 620
S D G G +R V +G C + +A+ +C C
Sbjct: 662 ESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPC 721
Query: 621 GGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVEV 680
T GT+ SP +P+ Y N NC+W +++ RI L F F+LE ++DF+ V
Sbjct: 722 LSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLES----QFDFLAV 777
Query: 681 RSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFS-DKDEC--- 736
+ G SP++ + G F G+E P +TS S+ +R+EF++D+++S RGF + + +EC
Sbjct: 778 KDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDP 837
Query: 737 -----AKDNGG-----------CQHECVNTFGSYLCRC--RNGYWLHENGHDCKEAGCAH 778
A+ G C+ + T G+ C +G + A C
Sbjct: 838 GIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGG 897
Query: 779 KISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMYD 838
S+ G + SP WP Y C W I + GH +K+TF F+ E + YD LE++D
Sbjct: 898 HFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELN----YDVLEVHD 953
Query: 839 GPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQ---------------- 882
GP+ L+P+LG + G++ P +S + ++L F +D S GF+
Sbjct: 954 GPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDP 1013
Query: 883 --AVH----------------STECGGRLKAE----VQTKELYSHAQ-------FGDNNY 913
VH S + G RL E + +SH GD
Sbjct: 1014 GIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCGGDVRG 1073
Query: 914 PS--------------EARCDWVIVAEDGYGVELTFRTFEVEEEADCGYDYMEAYDGYDS 959
PS C W + G GV+ F TF +E+ +DY+ +
Sbjct: 1074 PSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDH----HDYLLITENGSF 1129
Query: 960 SAPRLGRFCGSGPLEEIYSAG----DSLMIRFRTDDTINKKGFHARYT 1003
+ P L R GS L +AG +RF +D +I+ +GF+ ++
Sbjct: 1130 TQP-LARLTGS-DLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFS 1175
Score = 194 bits (494), Expect = 3e-49
Identities = 176/644 (27%), Positives = 261/644 (40%), Gaps = 124/644 (19%)
Query: 351 CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVE 410
CG L ++G +P FP+ YP C W I+V I L F S + + YD++
Sbjct: 1588 CGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN----YDFLY 1643
Query: 411 VRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEA----TC-- 464
+ DG +PL+G F K+PE + S+ + + + FRS ++ GF Y+A +C
Sbjct: 1644 IYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFD 1703
Query: 465 -GGDMNK-----------------DAGQIQSPN------YPDDYRPS---------KECV 491
G MN DAG + DD RP C
Sbjct: 1704 PGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCG 1763
Query: 492 WRITVSEGFHVGLTFQAFEIERHDSCAY----------------------DYLEVRDGPT 529
R T SEG + + H +C Y D +EV DGPT
Sbjct: 1764 SRSTGSEGTVLSPNYPKNYSVGH-NCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPT 1822
Query: 530 EESALIGHFCGYEKPEDVK-SSSNRLWMKFVSDGSINKAGFAANFFKEV------DECSW 582
++S+L+ G E + SS N++ ++F S G I GF +F + +CS
Sbjct: 1823 QQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGF--HFVYQAVPRTSSTQCSS 1880
Query: 583 PDHGGCEHRCVNTL---GSYKCACDPGYELAADKKM------------------CEVACG 621
R N S C+PGY L + C V CG
Sbjct: 1881 VPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCIVPCG 1940
Query: 622 GFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVEVR 681
G +TK GTI SPG+P+ Y N NCVW++ P I +Q F E N +D ++
Sbjct: 1941 GILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN----WDSLDFY 1996
Query: 682 SGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFS-DKDECAK-- 738
G +A G + G+ P ++ S SNN+ + F+SD +VS GF + + D C +
Sbjct: 1997 DGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQ 2056
Query: 739 -DNGGCQHECVNTFGSYLC-RCRNGYWLHENGH-DCKE--------------AGCAHKIS 781
+ G + G + +C GY L + H C A C +S
Sbjct: 2057 TPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAMS 2116
Query: 782 SVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMYDGPD 841
G + SP +P YPS +CTW I+ G V L F F E +D+LE+ G
Sbjct: 2117 DFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFS----TETIHDYLEVRSGSS 2172
Query: 842 SLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQAVH 885
+ ++GR G + P ++ L F+SD S ++GF V+
Sbjct: 2173 ETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVY 2216
Score = 187 bits (474), Expect = 6e-47
Identities = 137/474 (28%), Positives = 213/474 (44%), Gaps = 73/474 (15%)
Query: 462 ATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDY 521
A CGG++ +G I SPN+P Y S++C W ITV+ + + L F +F IE + YD+
Sbjct: 1586 APCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN----YDF 1641
Query: 522 LEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECS 581
L + DGP S LIG F + PE ++SSSN + + F SDGS++ GF + ++ E
Sbjct: 1642 LYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESC 1701
Query: 582 WPDHG--------GCEHRCVNTLGSYKCACDPGYELAADKKM------------------ 615
+ D G G +++ +T+ Y CD GY L +
Sbjct: 1702 F-DPGNIMNGTRLGMDYKLGSTVTYY---CDAGYVLQGYSTLTCIMGDDGRPGWNRALPS 1757
Query: 616 CEVACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKY 675
C CG T GT+ SP +PK Y NCV+ + P ++ + QF F+ +DV
Sbjct: 1758 CHAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDV--- 1814
Query: 676 DFVEVRSGLSPDAKLHGRFCGSETPEVI-TSQSNNMRVEFKSDNTVSKRGFRAHFF---- 730
VEV G + + L GS + E + S N + + F S ++ +GF HF
Sbjct: 1815 --VEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGF--HFVYQAV 1870
Query: 731 --SDKDECAK-DNGGCQHECVNTF---GSYLCRCRNGYWLHEN-GHDCKE---------- 773
+ +C+ N F S L C GY LH + C+
Sbjct: 1871 PRTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWND 1930
Query: 774 ------AGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQ 827
C ++ +GT+ SP +P+ Y + C W I+ G +++ F E +
Sbjct: 1931 SLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN- 1989
Query: 828 ECAYDHLEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGF 881
+D L+ YDG D+ AP LG + G+ P ++ ++++L F SD SV GF
Sbjct: 1990 ---WDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGF 2040
Score = 187 bits (474), Expect = 6e-47
Identities = 144/469 (30%), Positives = 218/469 (46%), Gaps = 64/469 (13%)
Query: 462 ATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDY 521
A CGG M+ +G I SP +P +Y S +C W I + GF V L F F E +DY
Sbjct: 2109 AQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTET----IHDY 2164
Query: 522 LEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECS 581
LEVR G +E S +IG G + P + S+++ + F SD S NK GF ++ S
Sbjct: 2165 LEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHI-VYQAYQLQS 2223
Query: 582 WPDHGGCEHRCVN----TLG-SYKCACDPGYELAADKKM----------------CEVAC 620
PD + V T+G + C PGY L + + CE C
Sbjct: 2224 CPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALC 2283
Query: 621 GGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVEV 680
GG IT +NGTI SPG+P EYP ++C W V P I + F V + E YDF+ V
Sbjct: 2284 GGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEP----IYDFITV 2339
Query: 681 RSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGF--------------- 725
G ++ G+F G+ E + S SN + ++F SD T S GF
Sbjct: 2340 WDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTS--GFFVLSYHAYQLRVCQP 2397
Query: 726 -----RAHFFSDKDECAKDNGGCQHECVNTF---GSYLCRCRNGYWLHENGHD--CKEAG 775
A ++ DE + +++C+ F G+ + CR G L +G C+
Sbjct: 2398 PPPVPNAEILTEDDE-FEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQVLC 2456
Query: 776 CAHKIS-SVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHL 834
A+++ G + SP +PD YP+ + C W+IS G+ + + F+ E+ +D L
Sbjct: 2457 PANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKE----FDVL 2512
Query: 835 EMYDGPDSLAPILGRFCGSKKPDPTVAS-GSSMFLRFYSDASVQRKGFQ 882
++YDGP+ +P+L G + S G +FL++ +D +KGF+
Sbjct: 2513 QVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFR 2561
Score = 184 bits (467), Expect = 4e-46
Identities = 137/465 (29%), Positives = 209/465 (44%), Gaps = 59/465 (12%)
Query: 462 ATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDY 521
A CG + G + SPNYP +Y + EC++ I V G + ++ + F + + D
Sbjct: 1239 AECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGD-----V 1293
Query: 522 LEVRDGPTEESALIGHFCGYE-KPEDVKSSSNRLWMKFVSDGSINKAGFAANFFK-EVDE 579
L++ DG + + L+G F G + + S+SN+LW++F SD GF + E+
Sbjct: 1294 LKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSH 1353
Query: 580 CSWPDHGGCEHRCVNTLGSYKCA-----CDPGYELAADKKM----------------CEV 618
C P ++ ++ G + + C+PGY L + C
Sbjct: 1354 CEDPGIPQFGYK-ISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIA 1412
Query: 619 ACGG-FITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDF 677
CGG F + +G I SPG+P Y N C+W + +SLQF F+ E + +D
Sbjct: 1413 ECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEAS----HDI 1468
Query: 678 VEVRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECA 737
+ V G + L GS PE I S N + ++F +D +SK GF F S
Sbjct: 1469 LRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATAC 1528
Query: 738 KDNGGCQHECVNTFG-----SYLCRCRNGYWLH-ENGHDCKE---------------AGC 776
+D G + N G + + +C GY L E C + A C
Sbjct: 1529 RDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPC 1588
Query: 777 AHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEM 836
++ G + SPN+P YP R+C W I+ A + + L F F IE + YD L +
Sbjct: 1589 GGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN----YDFLYI 1644
Query: 837 YDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGF 881
YDGPDS +P++G F SK P+ +S ++M L F SD SV GF
Sbjct: 1645 YDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGF 1689
Score = 176 bits (446), Expect = 1e-43
Identities = 138/482 (28%), Positives = 212/482 (43%), Gaps = 60/482 (12%)
Query: 451 ILGKGFFAAYEATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFE 510
++ G A CGG + +G I SP +P Y+ S C W I G + +TF+ F+
Sbjct: 882 VMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQ 941
Query: 511 IERHDSCAYDYLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGF- 569
E + YD LEV DGP S L+G + G + P+ + SSSN +++ F +D S + GF
Sbjct: 942 TELN----YDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFK 997
Query: 570 ------AANFFKEVDECSWPDHGGCEHRCVNTLGSYKCACDPGYELAADKKM-------- 615
N + +D P HG + + +CD GY L+ ++ +
Sbjct: 998 IHYESVTVNTYSCLDP-GIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWW 1056
Query: 616 ------CEVACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEG 669
C+ CGG + +GTI SPG+P+ YP + NC W V + F F LE
Sbjct: 1057 SHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLED 1116
Query: 670 NDVCKYDFVEVRSGLSPDAKLHGRFCGSETPEVITS-QSNNMRVE--FKSDNTVSKRGFR 726
+ +D++ + S L R GS+ P I + N R + F SD ++S GF
Sbjct: 1117 H----HDYLLITENGSFTQPL-ARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFN 1171
Query: 727 AHFFSDKDECAKDNGGCQHECVNTFG-----SYLCRCRNGYWLHENGH-DCKEAG----- 775
F E +D G Q+ F + C +GY L C G
Sbjct: 1172 ITFSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWS 1231
Query: 776 ---------CAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQH 826
C ++ EG L SPN+P Y + EC ++I AG + ++ F + Q
Sbjct: 1232 APLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQG 1291
Query: 827 QECAYDHLEMYDGPDSLAPILGRFCGSKKPDPTVASGSS-MFLRFYSDASVQRKGFQAVH 885
D L++YDG D +LG F G+ T++S S+ ++L F SD +GFQ V+
Sbjct: 1292 -----DVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVY 1346
Query: 886 ST 887
++
Sbjct: 1347 TS 1348
Score = 159 bits (401), Expect = 2e-38
Identities = 156/621 (25%), Positives = 261/621 (42%), Gaps = 115/621 (18%)
Query: 350 ACGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYV 409
ACG T++ ++G S+P FPN Y + + C W I PG+ I L FT + + YDY+
Sbjct: 240 ACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEK----YDYL 295
Query: 410 EVRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEA------- 462
E+ P G IP P++S + L + F + SN +GF A Y+
Sbjct: 296 EIEGS----EPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQGSSTLTHT 351
Query: 463 TCGGDMNKD----AGQIQSPNYPDD-----------YRPSKECVWRITVSEGFHVGLTFQ 507
T G++ + G I + P D +R S+E ++T +
Sbjct: 352 TSTGELEEHNRTTTGAIAVASTPADVTVSSVTAVTIHRLSEEQRVQVTSLRNSGLDPNTS 411
Query: 508 AFEIERHDSCAYDYLEVRDGP--------TEESALIGHFCGYEKPEDVKSSSNRLW---- 555
+ H + D R P T+E A++ H +K D KS +L+
Sbjct: 412 KDGLSPHPA---DTQSTRRRPRHAEQIERTKELAVVTH--RVKKAIDFKSRGFKLFPGKD 466
Query: 556 ----MKFVSDGSINKAGFAANFFKEVDECSWPDHGGCEHRCVNTLGSYKCACDPGYELAA 611
+++G I A +N + E P++G + + + +CD Y L
Sbjct: 467 NSNKFSILNEGGIKTA---SNLCPDPGE---PENGKRIGSDFSLGSTVQFSCDEDYVLQG 520
Query: 612 DKKM------------------CEV-ACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVA 652
K + C+V CG + +GT TSP +P +Y +N CVW + A
Sbjct: 521 AKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITA 580
Query: 653 PAQYR-ISLQFEVFELEGNDVCKYDFVEVRSG--LSPDAKLHGRFCGSETPEVITSQSNN 709
+ I + FE F+LE YD + + G + + GS P++I S S+
Sbjct: 581 VNTNKVIQINFEEFDLE----IGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQ 636
Query: 710 MRVEFKSDNTVSKRGFRAHFFS-DKDECA---------KDNGGCQHECVNTFGSYLCRCR 759
M + ++D +V GF+ ++ +K+ C ++ G + V F C+
Sbjct: 637 MWLHLQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRF-----ECQ 691
Query: 760 NGYWL-HENGHDCKEAG------------CAHKISSVEGTLASPNWPDKYPSRRECTWNI 806
G+ L E C+E C ++ GT+ SP++P+ Y + C W I
Sbjct: 692 FGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTI 751
Query: 807 SSTAGHRVKLTFNEFEIEQHQECAYDHLEMYDGPDSLAPILGRFCGSKKPDPTVASGSSM 866
S G R+ L+FN+F++E +D L + DG +PILG F G++ P ++ +
Sbjct: 752 ISDPGSRIHLSFNDFDLESQ----FDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSHIL 807
Query: 867 FLRFYSDASVQRKGFQAVHST 887
L F +D S+ +GF ++T
Sbjct: 808 RLEFQADHSMSGRGFNITYNT 828
Score = 143 bits (360), Expect = 9e-34
Identities = 160/648 (24%), Positives = 249/648 (38%), Gaps = 124/648 (19%)
Query: 461 EATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYD 520
+A CGGD+ +G I SP YP+ Y S C W + V+ G V F F +E H +D
Sbjct: 1064 DALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDH----HD 1119
Query: 521 YLEVRDGPTEESALIGHFCGYEKPEDVKS---SSNRLWMKFVSDGSINKAGFAANFFK-E 576
YL + + + L G + P + + + R ++F+SD SI+ GF F +
Sbjct: 1120 YLLITENGSFTQPL-ARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYN 1178
Query: 577 VDECSWPDHGGCEHRCVNTLG---SYKCACDPGYEL----------------AADKKMCE 617
++ C P R G + +C GY L +A C
Sbjct: 1179 LEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCV 1238
Query: 618 VACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDF 677
CG T G + SP +P Y N C++ + A I++ F L DV K
Sbjct: 1239 AECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLK--- 1295
Query: 678 VEVRSGLSPDAKLHGRFCGSETPEV-ITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDEC 736
+ G L G F G+ + ++S SN + +EF SD + GF+ + S +
Sbjct: 1296 --IYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSH 1353
Query: 737 AKDNG---------------------GCQHECVNTFGSYLCRCRNG---YWLHENGHDCK 772
+D G GC + GS L +C G W +
Sbjct: 1354 CEDPGIPQFGYKISDQGHFAGSTIIYGC-NPGYTLHGSSLLKCMTGERRAWDYPLPSCIA 1412
Query: 773 EAGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYD 832
E G K S G + SP +P Y + C W I G+ V L F F+ E ++D
Sbjct: 1413 ECGGRFKGES-SGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFD----TEASHD 1467
Query: 833 HLEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQAVHS----TE 888
L ++DGP +L GS P+ ++ + + ++F +D + + GF S T
Sbjct: 1468 ILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATA 1527
Query: 889 C-------------GGRLKA-----------EVQTKELYSHAQFGDNNY---PSE----A 917
C GR E+Q +E + Q +N Y PS A
Sbjct: 1528 CRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQV-ENRYFWQPSPPVCIA 1586
Query: 918 RCDWVIVAEDGYGVELTFRTFEVEEEADCGY------DYMEA-----------YD----- 955
C + G+ + F DC + DY+ + YD
Sbjct: 1587 PCGGNLTGSSGFILSPNF-PHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIY 1645
Query: 956 -GYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARY 1002
G DS++P +G F S E I S+ +++ + FR+D +++ GFH Y
Sbjct: 1646 DGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEY 1693
Score = 113 bits (282), Expect = 1e-24
Identities = 84/314 (26%), Positives = 138/314 (43%), Gaps = 46/314 (14%)
Query: 620 CGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVE 679
CGG + LNGTI SPG+P YP NC W ++A + RI + F+ F LE +YD++
Sbjct: 65 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEE----EYDYLS 120
Query: 680 VRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECAKD 739
+ G R G P +TS + + SD VS GF+ ++ + +
Sbjct: 121 LYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKV-YYEELQSSSCG 179
Query: 740 NGGCQHECVNTFGSYL-------CRCRNGYWLHENGHD--------------------CK 772
N G + V +G+ C GY L +GH C+
Sbjct: 180 NPGVPPKGV-LYGTRFDVGDKIRYSCVTGYIL--DGHPQLTCIANSVNTASWDFPVPICR 236
Query: 773 -EAGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAY 831
E C + G ++SP++P++Y + +CTW I + G + L F +F++E+ Y
Sbjct: 237 AEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEE----KY 292
Query: 832 DHLEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQAVHSTECGG 891
D+LE+ + P G P P +++ + + L F +D++ + +GF A + +
Sbjct: 293 DYLEI----EGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPY--QGSS 346
Query: 892 RLKAEVQTKELYSH 905
L T EL H
Sbjct: 347 TLTHTTSTGELEEH 360
Score = 111 bits (277), Expect = 4e-24
Identities = 81/292 (27%), Positives = 123/292 (42%), Gaps = 38/292 (13%)
Query: 463 TCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDYL 522
TCGG + G I+SP +P Y C W I E + + FQ+F +E YDYL
Sbjct: 64 TCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEE----YDYL 119
Query: 523 EVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECSW 582
+ DG + G+ P V S+ + ++ SD +++ GF +++E+ S
Sbjct: 120 SLYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKV-YYEELQSSSC 178
Query: 583 -----PDHGGCEHRCVNTLGSYKCACDPGYELAADKKM--------------------CE 617
P G + + +C GY L ++ E
Sbjct: 179 GNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAE 238
Query: 618 VACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDF 677
ACGG + +G I+SP +P EY N +C W +VA ISL F F++E KYD+
Sbjct: 239 DACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEE----KYDY 294
Query: 678 VEVRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHF 729
+E+ P L G P I S N +R+ F +D+ RGF A +
Sbjct: 295 LEIEGSEPPTIWL----SGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPY 342
Score = 108 bits (270), Expect = 3e-23
Identities = 83/299 (27%), Positives = 134/299 (44%), Gaps = 40/299 (13%)
Query: 461 EATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYD 520
EA CGG++ G I SP YPD+Y ++C W + V G + + F + E YD
Sbjct: 2280 EALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEP----IYD 2335
Query: 521 YLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGF----------- 569
++ V DGP + S IG F G E V S+SN++ +KF SD +GF
Sbjct: 2336 FITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSD--FTTSGFFVLSYHAYQLR 2393
Query: 570 ---------AANFFKEVDECSWPDHGGCEHRCV---NTLGSYKCACDPGYELAAD--KKM 615
A E DE D ++C+ +G+ C G L D +
Sbjct: 2394 VCQPPPPVPNAEILTEDDEFEIGDI--IRYQCLPGFTLVGNAILTCRLGERLQMDGAPPV 2451
Query: 616 CEVACGGFITKLN--GTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVC 673
C+V C +L+ G I SPG+P YP + C W + Y I++ E F+ E
Sbjct: 2452 CQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEK---- 2507
Query: 674 KYDFVEVRSGLSPDAKLHGRFCGSETPEV-ITSQSNNMRVEFKSDNTVSKRGFRAHFFS 731
++D ++V G + + + G + ITS + + +++ +D+ +K+GFR + +
Sbjct: 2508 EFDVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIA 2566
Score = 87.4 bits (215), Expect = 6e-17
Identities = 72/294 (24%), Positives = 121/294 (41%), Gaps = 68/294 (23%)
Query: 771 CKEAGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRV-KLTFNEFEIEQHQEC 829
CK C + GT SPN+P +Y S +C W I++ ++V ++ F EF++E
Sbjct: 543 CKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLE----I 598
Query: 830 AYDHLEMYDGPDSLAP--ILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQA---- 883
YD L + DG + P +L GS PD V+ S M+L +D SV GF+
Sbjct: 599 GYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKE 658
Query: 884 VHSTECG--GRLKAEVQTKELYSH-------AQFG------------DNN---------- 912
+ CG G ++ + +S+ QFG +NN
Sbjct: 659 IEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICI 718
Query: 913 ----------------------YPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGYDY 950
Y + C W I+++ G + L+F F++E + +D+
Sbjct: 719 FPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQ----FDF 774
Query: 951 MEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARYTS 1004
+ DG +P LG F G+ + S L + F+ D +++ +GF+ Y +
Sbjct: 775 LAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNT 828
Score = 70.1 bits (170), Expect = 1e-11
Identities = 37/114 (32%), Positives = 61/114 (53%), Gaps = 7/114 (6%)
Query: 345 LYKCPA-CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRL 403
L +C A CG + G +PG+P+ YP++ C W + V PG I +NFT +
Sbjct: 2276 LPRCEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPI-- 2333
Query: 404 CWYDYVEVRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFF 457
YD++ V DG + +P +G+F G+ E + ST +++ ++F S+ GFF
Sbjct: 2334 --YDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFH--SDFTTSGFF 2383
Score = 67.8 bits (164), Expect = 5e-11
Identities = 38/112 (33%), Positives = 55/112 (49%), Gaps = 4/112 (3%)
Query: 351 CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVE 410
CG + D +G +PGFP YPS C W I++ G + L F + S +DY+E
Sbjct: 2111 CGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNF----STETIHDYLE 2166
Query: 411 VRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEA 462
VR G + ++GR G +IP L ST + F S + +GF Y+A
Sbjct: 2167 VRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQA 2218
Score = 64.7 bits (156), Expect = 4e-10
Identities = 38/119 (31%), Positives = 55/119 (46%), Gaps = 8/119 (6%)
Query: 351 CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVE 410
CG TL+ G +PGFP GYP+ ++C W I +I + F S L + YDY+
Sbjct: 65 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEE----YDYLS 120
Query: 411 VRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYE----ATCG 465
+ DG+ R G +P P+ ST S + S + GF YE ++CG
Sbjct: 121 LYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCG 179
Score = 63.9 bits (154), Expect = 7e-10
Identities = 42/145 (28%), Positives = 61/145 (42%), Gaps = 8/145 (5%)
Query: 461 EATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYD 520
E CGG M +G I SP++P++Y + +C W I G + L F F++E YD
Sbjct: 238 EDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEE----KYD 293
Query: 521 YLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDEC 580
YLE+ L G P + S+ N L + FV+D + GF+A +
Sbjct: 294 YLEIEGSEPPTIWL----SGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQGSSTLT 349
Query: 581 SWPDHGGCEHRCVNTLGSYKCACDP 605
G E T G+ A P
Sbjct: 350 HTTSTGELEEHNRTTTGAIAVASTP 374
Score = 63.2 bits (152), Expect = 1e-09
Identities = 40/130 (30%), Positives = 66/130 (50%), Gaps = 5/130 (3%)
Query: 334 LSQGDIAQARKLYKCPA-CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLN 392
L G + + + KC A CG +G +PG+P Y +C W I PG I +
Sbjct: 877 LMDGKVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKIT 936
Query: 393 FTSMDLFKSRLCWYDYVEVRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNIL 452
F + F++ L YD +EV DG +PLLG + G ++P+ L S+ + +++ F + ++
Sbjct: 937 F---ERFQTELN-YDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRS 992
Query: 453 GKGFFAAYEA 462
GF YE+
Sbjct: 993 NNGFKIHYES 1002
Score = 62.0 bits (149), Expect = 3e-09
Identities = 32/104 (30%), Positives = 56/104 (53%), Gaps = 8/104 (7%)
Query: 889 CGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGY 948
CGG + A T +YS + YP+ C W++ G G+ + F + E Y
Sbjct: 2283 CGGNITAMNGT--IYSPGY--PDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPI----Y 2334
Query: 949 DYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDT 992
D++ +DG D ++P++G+F G+ LE +YS + ++I+F +D T
Sbjct: 2335 DFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFT 2378
Score = 61.2 bits (147), Expect = 5e-09
Identities = 35/116 (30%), Positives = 59/116 (50%), Gaps = 8/116 (6%)
Query: 889 CGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGY 948
CGG L T + + DNN C W I +G G+++ +F E +
Sbjct: 1939 CGGILTKRKGTILSPGYPEPYDNNL----NCVWKITVPEGAGIQVQVVSFATEHN----W 1990
Query: 949 DYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARYTS 1004
D ++ YDG D++APRLG + G+ + S ++L + F++D +++ GFH YT+
Sbjct: 1991 DSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTA 2046
Score = 56.6 bits (135), Expect = 1e-07
Identities = 31/97 (31%), Positives = 45/97 (46%), Gaps = 4/97 (4%)
Query: 912 NYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGYDYMEAYDGYDSSAPRLGRFCGSG 971
NYPS C W I G+GV L F F E +DY+E G ++ +GR G
Sbjct: 2130 NYPSSLDCTWTINLPIGFGVHLQFVNFSTETI----HDYLEVRSGSSETSTVIGRLSGPQ 2185
Query: 972 PLEEIYSAGDSLMIRFRTDDTINKKGFHARYTSTKFQ 1008
++S + F +D + NK+GFH Y + + Q
Sbjct: 2186 IPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQ 2222
Score = 56.2 bits (134), Expect = 2e-07
Identities = 35/114 (30%), Positives = 51/114 (44%), Gaps = 8/114 (7%)
Query: 889 CGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGY 948
CGG LK T E YP+ A C WVI+AE+ +++ F++F +EEE Y
Sbjct: 65 CGGTLKGLNGTIESPGFPY----GYPNGANCTWVIIAEERNRIQIVFQSFALEEE----Y 116
Query: 949 DYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARY 1002
DY+ YDG+ R G + S +R +D ++ GF Y
Sbjct: 117 DYLSLYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYY 170
Score = 54.7 bits (130), Expect = 4e-07
Identities = 38/118 (32%), Positives = 56/118 (47%), Gaps = 7/118 (5%)
Query: 888 ECGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCG 947
ECGGR K E + L F Y + RC W+I + G V L F F+ E
Sbjct: 1413 ECGGRFKGESSGRILSPGYPFP---YDNNLRCMWMIEVDPGNIVSLQFLAFDTE----AS 1465
Query: 948 YDYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARYTST 1005
+D + +DG + L GS E I+S + + I+F TD I+K GF +++S+
Sbjct: 1466 HDILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSS 1523
Score = 51.6 bits (122), Expect = 4e-06
Identities = 40/122 (32%), Positives = 60/122 (49%), Gaps = 7/122 (5%)
Query: 343 RKLYKCPA-CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKS 401
R L C A CG + G +P +P Y +CV+ I+V P E +V F F++
Sbjct: 1753 RALPSCHAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAV-PKEFVV--FGQFVFFQT 1809
Query: 402 RLCWYDYVEVRDGYWRKAPLLGRFCGDKIPEPL-VSTDSRLWVEFRSSSNILGKGFFAAY 460
L +D VEV DG +++ LL G E L +S+ +++ + F S I KGF Y
Sbjct: 1810 SL--HDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVY 1867
Query: 461 EA 462
+A
Sbjct: 1868 QA 1869
Score = 51.2 bits (121), Expect = 5e-06
Identities = 34/118 (28%), Positives = 57/118 (48%), Gaps = 7/118 (5%)
Query: 345 LYKCPA-CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRL 403
L +C A CG + + G +P +P Y + C++ I V G+ I ++ + L +
Sbjct: 1234 LPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQG-- 1291
Query: 404 CWYDYVEVRDGYWRKAPLLGRFCGDKIPE-PLVSTDSRLWVEFRSSSNILGKGFFAAY 460
D +++ DG + LLG F G + L ST ++LW+EF S + +GF Y
Sbjct: 1292 ---DVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVY 1346
Score = 51.2 bits (121), Expect = 5e-06
Identities = 29/93 (31%), Positives = 45/93 (48%), Gaps = 5/93 (5%)
Query: 911 NNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGYDYMEAYDGYDSSAPRLGRFCGS 970
++YP+ C W I E GY + + F+ E+E +D ++ YDG + +P L G
Sbjct: 2476 DSYPNLQMCAWSISVEKGYNITMFVEFFQTEKE----FDVLQVYDGPNIQSPVLISLSGD 2531
Query: 971 -GPLEEIYSAGDSLMIRFRTDDTINKKGFHARY 1002
I S G + +++ D NKKGF RY
Sbjct: 2532 YSSAFNITSNGHEVFLQWSADHGNNKKGFRIRY 2564
Score = 49.3 bits (116), Expect = 2e-05
Identities = 37/114 (32%), Positives = 51/114 (44%), Gaps = 12/114 (10%)
Query: 889 CGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGY 948
CGG ++ + + S F N Y + A C W IVAE G + L F F++EE+ Y
Sbjct: 241 CGGTMRG---SSGIISSPSF-PNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEK----Y 292
Query: 949 DYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARY 1002
DY+E + S P G I S + L + F TD +GF A Y
Sbjct: 293 DYLE----IEGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPY 342
Score = 47.8 bits (112), Expect = 5e-05
Identities = 34/116 (29%), Positives = 53/116 (45%), Gaps = 6/116 (5%)
Query: 348 CPACGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYD 407
CPA E D+TG +PG+P+ YP+ C W ISV G I + K +D
Sbjct: 2456 CPA-NELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKE----FD 2510
Query: 408 YVEVRDGYWRKAPLLGRFCGD-KIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEA 462
++V DG ++P+L GD + S +++++ + KGF Y A
Sbjct: 2511 VLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIA 2566
Score = 44.3 bits (103), Expect = 6e-04
Identities = 27/94 (28%), Positives = 44/94 (46%), Gaps = 6/94 (6%)
Query: 912 NYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGYDYMEAYDGYDSSAPRLGRFCGSG 971
NY + C + I + G G+ ++ RTF + + D ++ YDG D + LG F G+
Sbjct: 1260 NYENNHECIYSIQVQAGKGINISARTFHLAQG-----DVLKIYDGKDKTTHLLGAFTGAS 1314
Query: 972 PLE-EIYSAGDSLMIRFRTDDTINKKGFHARYTS 1004
+ S + L + F +D +GF YTS
Sbjct: 1315 MRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTS 1348
Score = 34.7 bits (78), Expect = 0.47
Identities = 20/56 (35%), Positives = 28/56 (50%), Gaps = 1/56 (1%)
Query: 948 YDYMEAYDGYDSSAPRLGRFCGSGPLEEI-YSAGDSLMIRFRTDDTINKKGFHARY 1002
+D +E YDG + L GS E + S+G+ + IRF + I KGFH Y
Sbjct: 1812 HDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVY 1867
>gi|92110053 CUB and Sushi multiple domains 2 [Homo sapiens]
Length = 3487
Score = 206 bits (525), Expect = 7e-53
Identities = 185/687 (26%), Positives = 284/687 (41%), Gaps = 163/687 (23%)
Query: 464 CGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDYLE 523
CGG++ + G I SP +P+ Y S CVW+I V EG + + +F E++ +D LE
Sbjct: 1796 CGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQN----WDSLE 1851
Query: 524 VRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANF----FKEVDE 579
V DG ++G F G P + S+SN+L++ F SD S++ AGF + E
Sbjct: 1852 VFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKTVGLSSCPE 1911
Query: 580 CSWPDHG--GCEHRCVNTLGSYKCACDPGYELAADKK----------------MCEVACG 621
+ P +G E VN + S++C +PGY L +C CG
Sbjct: 1912 PAVPSNGVKTGERYLVNDVVSFQC--EPGYALQGHAHISCMPGTVRRWNYPPPLCIAQCG 1969
Query: 622 GFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVEVR 681
G + ++ G I SPG+P YP+N +C W++ P + +QF F E N +D++E+R
Sbjct: 1970 GTVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPN----HDYIEIR 2025
Query: 682 SGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFS---------- 731
+G +++ GRF GSE P + S S+ V F SD++ ++ GF+ +
Sbjct: 2026 NGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQDLTYSHQISSF 2085
Query: 732 ----DKDECAKDNG--------------GCQ----HEC---------------VNTFGSY 754
D E + N GC+ EC N S
Sbjct: 2086 LRGFDLSELERTNSTPPVAASYVWDLDPGCEAYELQECPDPEPFANGIVRGAGYNVGQSV 2145
Query: 755 LCRCRNGYWLHENGH---DCK--------------EAGCAHKISSVEGTLASPNWPDKYP 797
C GY L GH C+ E C I+S GT+ SP +P Y
Sbjct: 2146 TFECLPGYQL--TGHPVLTCQHGTNRNWDHPLPKCEVPCGGNITSSNGTVYSPGFPSPYS 2203
Query: 798 SRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMYDGPDSLAPILGRFCGSKKPD 857
S ++C W I+ GH V+L + + E + D + ++DGP AP LG F S
Sbjct: 2204 SSQDCVWLITVPIGHGVRLNLSLLQTEP----SGDFITIWDGPQQTAPRLGVFTRSMAKK 2259
Query: 858 PTVASGSSMFLRFYSDAS---VQRKGFQAVHSTEC------------------------- 889
+S + + L+F+ DA+ + F A T+C
Sbjct: 2260 TVQSSSNQVLLKFHRDAATGGIFAIAFSAYPLTKCPPPTILPNAEVVTENEEFNIGDIVR 2319
Query: 890 -----GGRLKA-EVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELT--------- 934
G L E+ T +L ++ QF E C + D GV L+
Sbjct: 2320 YRCLPGFTLVGNEILTCKLGTYLQFEGPPPICEVHCPTNELLTDSTGVILSQSYPGSYPQ 2379
Query: 935 FRT--FEVEEEADCG-------------YDYMEAYDGYDSSAPRLGRFCG--SGPLEEIY 977
F+T + V E D YD E +DG +P L G S PL +
Sbjct: 2380 FQTCSWLVRVEPDYNISLTVEYFLSEKQYDEFEIFDGPSGQSPLLKALSGNYSAPL-IVT 2438
Query: 978 SAGDSLMIRFRTDDTINKKGFHARYTS 1004
S+ +S+ +R+ +D N+KGF RY++
Sbjct: 2439 SSSNSVYLRWSSDHAYNRKGFKIRYSA 2465
Score = 195 bits (495), Expect = 2e-49
Identities = 138/464 (29%), Positives = 210/464 (45%), Gaps = 57/464 (12%)
Query: 462 ATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDY 521
A CG + G + SPN+P +Y + EC++ I G + L +AFE+ D
Sbjct: 1096 AECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARAFELSEGD-----V 1150
Query: 522 LEVRDGPTEESALIGHFCGYEKPE-DVKSSSNRLWMKFVSDGSINKAGFAANFFK-EVDE 579
L+V DG + L+G F E + S+S+ LW+ F++D GF +F E+ +
Sbjct: 1151 LKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENTSKGFELHFSSFELIK 1210
Query: 580 CS---WPDHGGCEHRCVNTLGS-YKCACDPGYELAADKKM----------------CEVA 619
C P G H + GS +CDPGY L +++ C
Sbjct: 1211 CEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEELLCLSGERRTWDRPLPTCVAE 1270
Query: 620 CGGFIT-KLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFV 678
CGG + +++G + SPG+P Y N NC+W + A A I L F VF+ E +D +
Sbjct: 1271 CGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEE----VHDVL 1326
Query: 679 EVRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFF-----SDK 733
+ G L G P+ + S N++ ++F +D SK+GF F S
Sbjct: 1327 RIWDGPVESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQFSVSTATSCN 1386
Query: 734 DECAKDNGGCQHECVNTFGSYLCRCRNGYWLHENGH-DCKE---------------AGCA 777
D NG + S + +C GY L + C + A C
Sbjct: 1387 DPGIPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQPSPPTCIAPCG 1446
Query: 778 HKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMY 837
++ G + SPN+P+ YP +EC W ++ + + + L FN F +E YD L +Y
Sbjct: 1447 GDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEP----GYDFLHIY 1502
Query: 838 DGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGF 881
DG DSL+P++G F GS+ P +S +S+FL F SDASV GF
Sbjct: 1503 DGRDSLSPLIGSFYGSQLPGRIESSSNSLFLAFRSDASVSNAGF 1546
Score = 194 bits (493), Expect = 4e-49
Identities = 180/650 (27%), Positives = 271/650 (41%), Gaps = 129/650 (19%)
Query: 463 TCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDYL 522
+C + +G + SPNYP+DY CVW I + L F ++E +D+L
Sbjct: 577 SCFFNFTSPSGVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDIDVEPQ----FDFL 632
Query: 523 EVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANF--FKEVDEC 580
++DG T E+ ++G F G + P + SS + ++F +D S K GF F F+ +EC
Sbjct: 633 VIKDGATAEAPVLGTFSGNQLPSSITSSGHVARLEFQTDHSTGKRGFNITFTTFRH-NEC 691
Query: 581 SWPDHGG--------------------CEHRCVNTLGSYKCAC---DPGYELAADKKMCE 617
PD G C+ + T GS C + + CE
Sbjct: 692 --PDPGVPVNGKRFGDSLQLGSSISFLCDEGFLGTQGSETITCVLKEGSVVWNSAVLRCE 749
Query: 618 VACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDF 677
CGG +T +GTI SPGWP Y +C W + A Y I + F+ F+ E N YD
Sbjct: 750 APCGGHLTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTEVN----YDT 805
Query: 678 VEVRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFS---DKD 734
+EVR G + A L G + G++ P+ + S SN + + F +D + S GF+ + + D
Sbjct: 806 LEVRDGRTYSAPLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHSDIGFQLRYETITLQSD 865
Query: 735 ECAKDN---GGCQHECVNTFGSYLC-RCRNGYWLHENGH-DCK------------EAGCA 777
C G +H G+ + C +GY L + +C+ EA C
Sbjct: 866 HCLDPGIPVNGQRHGNDFYVGALVTFSCDSGYTLSDGEPLECEPNFQWSRALPSCEALCG 925
Query: 778 HKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMY 837
I GT+ SP +PD YP+ CTW I ++ G V TF+ F H E +D+L +
Sbjct: 926 GFIQGSSGTILSPGFPDFYPNNLNCTWIIETSHGKGVFFTFHTF----HLESGHDYLLIT 981
Query: 838 DGPDSLAPILGRFCGSKKPDPTVASGSSMF---LRFYSDASVQ----------------- 877
+ P L + GS+ P P A F +RF SD S+
Sbjct: 982 ENGSFTQP-LRQLTGSRLPAPISAGLYGNFTAQVRFISDFSMSYEGFNITFSEYDLEPCE 1040
Query: 878 ---------RKGFQ------AVHSTECGGRLKAEVQT------KELYSH------AQFGD 910
RKG Q S G RL+ + + L+S A+ G+
Sbjct: 1041 EPEVPAYSIRKGLQFGVGDTLTFSCFPGYRLEGTARITCLGGRRRLWSSPLPRCVAECGN 1100
Query: 911 N---------------NYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGYDYMEAYD 955
+ NY + C + I + G G++L R FE+ E D ++ YD
Sbjct: 1101 SVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARAFELSEG-----DVLKVYD 1155
Query: 956 GYDSSAPRLGRFCGSGPL-EEIYSAGDSLMIRFRTDDTINKKGFHARYTS 1004
G ++SA LG F S + + S SL + F TD KGF ++S
Sbjct: 1156 GNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENTSKGFELHFSS 1205
Score = 192 bits (487), Expect = 2e-48
Identities = 130/468 (27%), Positives = 224/468 (47%), Gaps = 57/468 (12%)
Query: 464 CGGDMNKDAGQIQSPNYPDDYRPSKECVWRIT-VSEGFHVGLTFQAFEIERHDSCAYDYL 522
C + +G I SPN+P Y + CVW IT ++ + L F+ F++ER YD L
Sbjct: 405 CDAHLRGPSGIITSPNFPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLER----GYDTL 460
Query: 523 EVRDGPTE--ESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDEC 580
V DG + + ++ G P+ + S+++++W+ F +DGS + GF A++ +E+++
Sbjct: 461 TVGDGGQDGDQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKASY-EEIEQG 519
Query: 581 SW-----PDHGGCEHRCVNTLGSYKCACDPGYELAADKKM--------------CEVACG 621
S P +G E + + K C P +EL K + C +C
Sbjct: 520 SCGDPGIPAYGRREGSRFHHGDTLKFECQPAFELVGQKAITCQKNNQWSAKKPGCVFSCF 579
Query: 622 GFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVEVR 681
T +G + SP +P++Y + +CVW ++A + RI L F ++E ++DF+ ++
Sbjct: 580 FNFTSPSGVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDIDVEP----QFDFLVIK 635
Query: 682 SGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECAKDNG 741
G + +A + G F G++ P ITS + R+EF++D++ KRGF F + + D G
Sbjct: 636 DGATAEAPVLGTFSGNQLPSSITSSGHVARLEFQTDHSTGKRGFNITFTTFRHNECPDPG 695
Query: 742 G--------------------CQHECVNTFGSYLCRC--RNGYWLHENGHDCKEAGCAHK 779
C + T GS C + G + + EA C
Sbjct: 696 VPVNGKRFGDSLQLGSSISFLCDEGFLGTQGSETITCVLKEGSVVWNSAVLRCEAPCGGH 755
Query: 780 ISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMYDG 839
++S GT+ SP WP Y C W I + G+ +K+TF+ F+ E + YD LE+ DG
Sbjct: 756 LTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTEVN----YDTLEVRDG 811
Query: 840 PDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQAVHST 887
AP++G + G++ P +++ + ++L F +D S GFQ + T
Sbjct: 812 RTYSAPLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHSDIGFQLRYET 859
Score = 176 bits (445), Expect = 1e-43
Identities = 168/649 (25%), Positives = 266/649 (40%), Gaps = 125/649 (19%)
Query: 461 EATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYD 520
EA CGG + +G I SP +P Y+ + C W I G+ + +TF F+ E + YD
Sbjct: 749 EAPCGGHLTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTEVN----YD 804
Query: 521 YLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFK---EV 577
LEVRDG T + LIG + G + P+ + S+SN L++ F +D S + GF + +
Sbjct: 805 TLEVRDGRTYSAPLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHSDIGFQLRYETITLQS 864
Query: 578 DECSWPD-------HGGCEHRCVNTLGSYKC------------ACDPGYELAADKKMCEV 618
D C P HG + V L ++ C C+P ++ + CE
Sbjct: 865 DHCLDPGIPVNGQRHGNDFY--VGALVTFSCDSGYTLSDGEPLECEPNFQWSRALPSCEA 922
Query: 619 ACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFV 678
CGGFI +GTI SPG+P YP N NC W + + F F LE +D++
Sbjct: 923 LCGGFIQGSSGTILSPGFPDFYPNNLNCTWIIETSHGKGVFFTFHTFHLESG----HDYL 978
Query: 679 EVRSGLSPDAKLHGRFCGSETPEVITS---QSNNMRVEFKSDNTVSKRGFRAHFFS-DKD 734
+ S L + GS P I++ + +V F SD ++S GF F D +
Sbjct: 979 LITENGSFTQPLR-QLTGSRLPAPISAGLYGNFTAQVRFISDFSMSYEGFNITFSEYDLE 1037
Query: 735 ECAKD-------NGGCQHECVNTFGSYLCRCRNGYWLHENGHDCKEAG------------ 775
C + G Q +T C GY L G
Sbjct: 1038 PCEEPEVPAYSIRKGLQFGVGDTL---TFSCFPGYRLEGTARITCLGGRRRLWSSPLPRC 1094
Query: 776 ---CAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYD 832
C + ++ +GTL SPN+P Y + EC ++I + G ++L FE+ + D
Sbjct: 1095 VAECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARAFELSEG-----D 1149
Query: 833 HLEMYDGPDSLAPILGRFCGSKKPDPTV-ASGSSMFLRFYSDASVQRKGFQ--------- 882
L++YDG ++ A +LG F S+ T+ ++ SS++L F +DA KGF+
Sbjct: 1150 VLKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENTSKGFELHFSSFELI 1209
Query: 883 ------------AVH------------STECGGRLKAEVQTKELYSHAQFGDNNYPS-EA 917
VH S + G L+ + L + D P+ A
Sbjct: 1210 KCEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEELLCLSGERRTWDRPLPTCVA 1269
Query: 918 RCDWVI-------VAEDGYGVELTFR---TFEVEEEADCG-------------YDYMEAY 954
C + V GY + +E EA C +D + +
Sbjct: 1270 ECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEEVHDVLRIW 1329
Query: 955 DGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARYT 1003
DG S L G ++++S +S++++F TD +K+GF +++
Sbjct: 1330 DGPVESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQFS 1378
Score = 175 bits (443), Expect = 2e-43
Identities = 132/469 (28%), Positives = 205/469 (43%), Gaps = 63/469 (13%)
Query: 462 ATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDY 521
A CGG G + SPNYP +Y + C++ +TV + + V F F + D
Sbjct: 1617 APCGGQYVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFH-----TALNDV 1671
Query: 522 LEVRDGPTEESALIGHFCGYEKPEDVK-SSSNRLWMKFVSDGSINKAGFAANFFKEVDEC 580
+EV DG ++ S L+ G E + ++SN++ +KF + G GF +
Sbjct: 1672 VEVHDGHSQHSRLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPARGFHFVYQAVPRTS 1731
Query: 581 SWPDHGGCEHRCVNTLGS-------YKCACDPGYELAADKKM------------------ 615
+ E R LGS + C+ GY L ++
Sbjct: 1732 ATQCSSVPEPRYGKRLGSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVSAPT 1791
Query: 616 CEVACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKY 675
C V CGG +T+ GTI SPG+P+ Y + NCVW++V P I +Q F E N +
Sbjct: 1792 CVVPCGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQN----W 1847
Query: 676 DFVEVRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHF----FS 731
D +EV G + G F G+ P ++ S SN + + F SD +VS GF + S
Sbjct: 1848 DSLEVFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKTVGLS 1907
Query: 732 DKDECAKDNGGC---QHECVNTFGSYLCRCRNGYWLHENGH-DCKE-------------- 773
E A + G + VN S+ +C GY L + H C
Sbjct: 1908 SCPEPAVPSNGVKTGERYLVNDVVSF--QCEPGYALQGHAHISCMPGTVRRWNYPPPLCI 1965
Query: 774 AGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDH 833
A C + +EG + SP +P YPS +C+W I+ G + F F E + +D+
Sbjct: 1966 AQCGGTVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPN----HDY 2021
Query: 834 LEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQ 882
+E+ +GP + ++GRF GS+ P +++ + F+SD S R GF+
Sbjct: 2022 IEIRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFK 2070
Score = 167 bits (424), Expect = 4e-41
Identities = 124/469 (26%), Positives = 196/469 (41%), Gaps = 58/469 (12%)
Query: 462 ATCGGDMNKD-AGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYD 520
A CGG + + +GQ+ SP YP Y + C+W I G +GL F F+ E +D
Sbjct: 1269 AECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEE----VHD 1324
Query: 521 YLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEV--- 577
L + DGP E L+ G P+D+ S+ N + ++F +D +K GFA F
Sbjct: 1325 VLRIWDGPVESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQFSVSTATS 1384
Query: 578 -DECSWPDHGGCEHRCVNTLGSYKCACDPGYELAADKKM-----------------CEVA 619
++ P +G S CDPGY L ++ C
Sbjct: 1385 CNDPGIPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQPSPPTCIAP 1444
Query: 620 CGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVE 679
CGG +T +G I SP +P+ YP K C W+V Y I+L F +F LE YDF+
Sbjct: 1445 CGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEPG----YDFLH 1500
Query: 680 VRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECAKD 739
+ G + L G F GS+ P I S SN++ + F+SD +VS GF + + E D
Sbjct: 1501 IYDGRDSLSPLIGSFYGSQLPGRIESSSNSLFLAFRSDASVSNAGFVIDYTENPRESCFD 1560
Query: 740 NGGCQH-----ECVNTFGSYLCRCRNGYWLH-----------------ENGHDCKEAGCA 777
G ++ + S C GY + N A C
Sbjct: 1561 PGSIKNGTRVGSDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNNPRPVCTAPCG 1620
Query: 778 HKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMY 837
+ +G + SPN+P Y S + C + ++ + + F +F D +E++
Sbjct: 1621 GQYVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDY---VVFGQFAF--FHTALNDVVEVH 1675
Query: 838 DGPDSLAPILGRFCGSKKPDP-TVASGSSMFLRFYSDASVQRKGFQAVH 885
DG + +L GS + +A+ + + ++F + +GF V+
Sbjct: 1676 DGHSQHSRLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPARGFHFVY 1724
Score = 167 bits (422), Expect = 6e-41
Identities = 135/513 (26%), Positives = 216/513 (42%), Gaps = 102/513 (19%)
Query: 462 ATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDY 521
A CGG + + G I SP +P +Y + +C W+I + GF + F F E + +DY
Sbjct: 1966 AQCGGTVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPN----HDY 2021
Query: 522 LEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGF------------ 569
+E+R+GP E S ++G F G E P + S+S+ + F SD S N+ GF
Sbjct: 2022 IEIRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQDLTYSHQ 2081
Query: 570 ----------------------AANFFKEVD---------ECSWPD---HGGCEHRCVNT 595
AA++ ++D EC P+ +G N
Sbjct: 2082 ISSFLRGFDLSELERTNSTPPVAASYVWDLDPGCEAYELQECPDPEPFANGIVRGAGYNV 2141
Query: 596 LGSYKCACDPGYELAADKKM----------------CEVACGGFITKLNGTITSPGWPKE 639
S C PGY+L + CEV CGG IT NGT+ SPG+P
Sbjct: 2142 GQSVTFECLPGYQLTGHPVLTCQHGTNRNWDHPLPKCEVPCGGNITSSNGTVYSPGFPSP 2201
Query: 640 YPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVEVRSGLSPDAKLHGRFCGSET 699
Y ++++CVW + P + + L + + E + DF+ + G A G F S
Sbjct: 2202 YSSSQDCVWLITVPIGHGVRLNLSLLQTEPSG----DFITIWDGPQQTAPRLGVFTRSMA 2257
Query: 700 PEVITSQSNNMRVEFKSDNTVSKRGFRAHFFS-------------DKDECAKDNGG---- 742
+ + S SN + ++F D + G A FS E +N
Sbjct: 2258 KKTVQSSSNQVLLKFHRD--AATGGIFAIAFSAYPLTKCPPPTILPNAEVVTENEEFNIG 2315
Query: 743 --CQHECVNTF---GSYLCRCRNGYWLH-ENGHDCKEAGCA--HKISSVEGTLASPNWPD 794
++ C+ F G+ + C+ G +L E E C ++ G + S ++P
Sbjct: 2316 DIVRYRCLPGFTLVGNEILTCKLGTYLQFEGPPPICEVHCPTNELLTDSTGVILSQSYPG 2375
Query: 795 KYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMYDGPDSLAPILGRFCGS- 853
YP + C+W + + + LT F E+ YD E++DGP +P+L G+
Sbjct: 2376 SYPQFQTCSWLVRVEPDYNISLTVEYFLSEKQ----YDEFEIFDGPSGQSPLLKALSGNY 2431
Query: 854 KKPDPTVASGSSMFLRFYSDASVQRKGFQAVHS 886
P +S +S++LR+ SD + RKGF+ +S
Sbjct: 2432 SAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRYS 2464
Score = 166 bits (420), Expect = 1e-40
Identities = 169/687 (24%), Positives = 260/687 (37%), Gaps = 163/687 (23%)
Query: 464 CGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDYLE 523
C ++ G ++SP +P Y C W IT E + L FQ+F +E +D L
Sbjct: 26 CTFQLHGPNGTVESPGFPYGYPNYANCTWTITAEEQHRIQLVFQSFALEED----FDVLS 81
Query: 524 VRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEV---DEC 580
V DGP + L G++ P + S++ L ++ +SD +++ GF A + EV C
Sbjct: 82 VFDGPPQPENLRTRLTGFQLPATIVSAATTLSLRLISDYAVSAQGFHATY--EVLPSHTC 139
Query: 581 SWPDH--GGCEHRCVNTLGS---YKC------------ACDPGYELAADKKM------CE 617
P G + LG Y C C G E +A +
Sbjct: 140 GNPGRLPNGIQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSCRAD 199
Query: 618 VACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDF 677
ACGG + +G I+SP +P EY N +C W ++A I+L F F+LE YDF
Sbjct: 200 DACGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDG----YDF 255
Query: 678 VEVRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECA 737
+EV +G + F G+ P + S N +R+ F SD +RGF A + K
Sbjct: 256 LEV-TGTEGSSLW---FTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQVKKQIEL 311
Query: 738 KDNG--------GCQHECVNT-----FGSYLC------------------------RCRN 760
K G Q V T G +C C
Sbjct: 312 KSRGVKLMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSDFRLGSSVQFTCNE 371
Query: 761 GYWLH------------------ENGHDCKEAGCAHKISSVEGTLASPNWPDKYPSRREC 802
GY L ++ C+ C + G + SPN+P +Y + C
Sbjct: 372 GYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPNFPIQYDNNAHC 431
Query: 803 TWNISSTAGHRV-KLTFNEFEIEQHQECAYDHLEMYDG--PDSLAPILGRFCGSKKPDPT 859
W I++ +V KL F EF++E+ YD L + DG +L G+ PD
Sbjct: 432 VWIITALNPSKVIKLAFEEFDLER----GYDTLTVGDGGQDGDQKTVLYILTGTSVPDLI 487
Query: 860 VASGSSMFLRFYSDASVQRKGFQA----VHSTECG------------------------- 890
V++ M+L F +D S GF+A + CG
Sbjct: 488 VSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGSCGDPGIPAYGRREGSRFHHGDTLKFEC 547
Query: 891 -------GRLKAEVQTKELYSHAQFG-----------------DNNYPSE----ARCDWV 922
G+ Q +S + G NYP + C W+
Sbjct: 548 QPAFELVGQKAITCQKNNQWSAKKPGCVFSCFFNFTSPSGVVLSPNYPEDYGNHLHCVWL 607
Query: 923 IVAEDGYGVELTFRTFEVEEEADCGYDYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDS 982
I+A + L F +VE + +D++ DG + AP LG F G+ I S+G
Sbjct: 608 ILARPESRIHLAFNDIDVEPQ----FDFLVIKDGATAEAPVLGTFSGNQLPSSITSSGHV 663
Query: 983 LMIRFRTDDTINKKGFHARYTSTKFQD 1009
+ F+TD + K+GF+ +T+ + +
Sbjct: 664 ARLEFQTDHSTGKRGFNITFTTFRHNE 690
Score = 164 bits (415), Expect = 4e-40
Identities = 177/693 (25%), Positives = 267/693 (38%), Gaps = 179/693 (25%)
Query: 464 CGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDYLE 523
CGG + +G I SP++P +Y + +C W I G + L F F++E YD+LE
Sbjct: 202 CGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLED----GYDFLE 257
Query: 524 VRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFF--KEVDECS 581
V TE S+L F G P V SS N L + F SDG+ + GF+A + K+++ S
Sbjct: 258 VTG--TEGSSL--WFTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQVKKQIELKS 313
Query: 582 -----WPDHGGCEHRCVNT----------------------------LGS-YKCACDPGY 607
P + V T LGS + C+ GY
Sbjct: 314 RGVKLMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSDFRLGSSVQFTCNEGY 373
Query: 608 ELAADKKM------------------CEVA-CGGFITKLNGTITSPGWPKEYPTNKNCVW 648
+L K++ C C + +G ITSP +P +Y N +CVW
Sbjct: 374 DLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPNFPIQYDNNAHCVW 433
Query: 649 QVVA--PAQYRISLQFEVFELEGNDVCKYDFVEVRSGLSPDAKLHGRFC--GSETPEVIT 704
+ A P++ I L FE F+LE YD + V G + + G+ P++I
Sbjct: 434 IITALNPSKV-IKLAFEEFDLERG----YDTLTVGDGGQDGDQKTVLYILTGTSVPDLIV 488
Query: 705 SQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECAKDNG----------------GCQHECV 748
S ++ M + F++D + S GF+A + + D G + EC
Sbjct: 489 STNHQMWLLFQTDGSGSSLGFKASYEEIEQGSCGDPGIPAYGRREGSRFHHGDTLKFECQ 548
Query: 749 NTF---GSYLCRC-RNGYWLHENGHDCKEAGCAHK----ISSVEGTLASPNWPDKYPSRR 800
F G C +N W K+ GC +S G + SPN+P+ Y +
Sbjct: 549 PAFELVGQKAITCQKNNQW------SAKKPGCVFSCFFNFTSPSGVVLSPNYPEDYGNHL 602
Query: 801 ECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMYDGPDSLAPILGRFCG-------- 852
C W I + R+ L FN+ ++E +D L + DG + AP+LG F G
Sbjct: 603 HCVWLILARPESRIHLAFNDIDVEPQ----FDFLVIKDGATAEAPVLGTFSGNQLPSSIT 658
Query: 853 ------------------------------SKKPDPTVASGSSMF---LRFYSDAS-VQR 878
++ PDP V F L+ S S +
Sbjct: 659 SSGHVARLEFQTDHSTGKRGFNITFTTFRHNECPDPGVPVNGKRFGDSLQLGSSISFLCD 718
Query: 879 KGFQAVHSTE-----------------------CGGRLKAEVQTKELYSHAQFGDNNYPS 915
+GF +E CGG L + T F Y
Sbjct: 719 EGFLGTQGSETITCVLKEGSVVWNSAVLRCEAPCGGHLTSPSGTILSPGWPGF----YKD 774
Query: 916 EARCDWVIVAEDGYGVELTFRTFEVEEEADCGYDYMEAYDGYDSSAPRLGRFCGSGPLEE 975
C WVI A+ GY +++TF F+ E YD +E DG SAP +G + G+ +
Sbjct: 775 ALSCAWVIEAQPGYPIKITFDRFKTE----VNYDTLEVRDGRTYSAPLIGVYHGTQVPQF 830
Query: 976 IYSAGDSLMIRFRTDDTINKKGFHARYTSTKFQ 1008
+ S + L + F TD + + GF RY + Q
Sbjct: 831 LISTSNYLYLLFSTDKSHSDIGFQLRYETITLQ 863
Score = 139 bits (350), Expect = 1e-32
Identities = 149/573 (26%), Positives = 229/573 (39%), Gaps = 123/573 (21%)
Query: 350 ACGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYV 409
ACG TL+ +G S+P FP+ Y + + C W I G+ I L F L YD++
Sbjct: 201 ACGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDG----YDFL 256
Query: 410 EVR----DGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEATCG 465
EV W F G +P P++S+ + L + F S N +GF A Y+
Sbjct: 257 EVTGTEGSSLW--------FTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQV--- 305
Query: 466 GDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDYLEVR 525
QI+ + PSK+ + +V VG++ + H+ C + R
Sbjct: 306 ------KKQIELKSRGVKLMPSKDNSQKTSVLT--QVGVS------QGHNMCPDPGIPER 351
Query: 526 DGPTEESALIGHFCGYEKPE--DVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECSWP 583
+G + E D++ S MK VSD FAA W
Sbjct: 352 GKRLGSDFRLGSSVQFTCNEGYDLQGSKRITCMK-VSD------MFAA----------WS 394
Query: 584 DHGGCEHRCVNTLGSYKCACDPGYELAADKKMCEV-ACGGFITKLNGTITSPGWPKEYPT 642
DH + +C C + +G ITSP +P +Y
Sbjct: 395 DH---------------------------RPVCRARMCDAHLRGPSGIITSPNFPIQYDN 427
Query: 643 NKNCVWQVVA--PAQYRISLQFEVFELEGNDVCKYDFVEV-RSGLSPDAK-LHGRFCGSE 698
N +CVW + A P++ I L FE F+LE YD + V G D K + G+
Sbjct: 428 NAHCVWIITALNPSKV-IKLAFEEFDLERG----YDTLTVGDGGQDGDQKTVLYILTGTS 482
Query: 699 TPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECAKDNG----------------G 742
P++I S ++ M + F++D + S GF+A + + D G
Sbjct: 483 VPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGSCGDPGIPAYGRREGSRFHHGDT 542
Query: 743 CQHECVNTF---GSYLCRC-RNGYWLHENGHDCKEAGCA----HKISSVEGTLASPNWPD 794
+ EC F G C +N W K+ GC +S G + SPN+P+
Sbjct: 543 LKFECQPAFELVGQKAITCQKNNQW------SAKKPGCVFSCFFNFTSPSGVVLSPNYPE 596
Query: 795 KYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMYDGPDSLAPILGRFCGSK 854
Y + C W I + R+ L FN+ ++E +D L + DG + AP+LG F G++
Sbjct: 597 DYGNHLHCVWLILARPESRIHLAFNDIDVEPQ----FDFLVIKDGATAEAPVLGTFSGNQ 652
Query: 855 KPDPTVASGSSMFLRFYSDASVQRKGFQAVHST 887
P +SG L F +D S ++GF +T
Sbjct: 653 LPSSITSSGHVARLEFQTDHSTGKRGFNITFTT 685
Score = 108 bits (269), Expect = 3e-23
Identities = 80/293 (27%), Positives = 127/293 (43%), Gaps = 32/293 (10%)
Query: 461 EATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYD 520
E CGG++ G + SP +P Y S++CVW ITV G V L + E + D
Sbjct: 2179 EVPCGGNITSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTEP----SGD 2234
Query: 521 YLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDEC 580
++ + DGP + + +G F + V+SSSN++ +KF D + A + +C
Sbjct: 2235 FITIWDGPQQTAPRLGVFTRSMAKKTVQSSSNQVLLKFHRDAATGGIFAIAFSAYPLTKC 2294
Query: 581 SWPD-----HGGCEHRCVNTLGSYKCACDPGYELAADK----------------KMCEVA 619
P E+ N + C PG+ L ++ +CEV
Sbjct: 2295 PPPTILPNAEVVTENEEFNIGDIVRYRCLPGFTLVGNEILTCKLGTYLQFEGPPPICEVH 2354
Query: 620 C--GGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDF 677
C +T G I S +P YP + C W V Y ISL E F E +YD
Sbjct: 2355 CPTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSEK----QYDE 2410
Query: 678 VEVRSGLSPDAKLHGRFCGS-ETPEVITSQSNNMRVEFKSDNTVSKRGFRAHF 729
E+ G S + L G+ P ++TS SN++ + + SD+ +++GF+ +
Sbjct: 2411 FEIFDGPSGQSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRY 2463
Score = 91.3 bits (225), Expect = 4e-18
Identities = 80/303 (26%), Positives = 125/303 (41%), Gaps = 77/303 (25%)
Query: 769 HDCKEAG--CAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQH 826
H + AG C ++ GT+ SP +P YP+ CTW I++ HR++L F F +E+
Sbjct: 17 HHPRSAGQNCTFQLHGPNGTVESPGFPYGYPNYANCTWTITAEEQHRIQLVFQSFALEED 76
Query: 827 QECAYDHLEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQAVH- 885
+D L ++DGP + R G + P V++ +++ LR SD +V +GF A +
Sbjct: 77 ----FDVLSVFDGPPQPENLRTRLTGFQLPATIVSAATTLSLRLISDYAVSAQGFHATYE 132
Query: 886 ---STECG--GRLKAEVQTKELYS-----------------HA----QFGDNN------- 912
S CG GRL +Q ++ HA G N
Sbjct: 133 VLPSHTCGNPGRLPNGIQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFP 192
Query: 913 -------------------------YPSE----ARCDWVIVAEDGYGVELTFRTFEVEEE 943
+PSE A C W I+AE G + L F F++E+
Sbjct: 193 LPSCRADDACGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLED- 251
Query: 944 ADCGYDYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARYT 1003
GYD++E SS F G+ + S+ + L + F +D ++GF A+Y
Sbjct: 252 ---GYDFLEVTGTEGSSL----WFTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQ 304
Query: 1004 STK 1006
K
Sbjct: 305 VKK 307
Score = 73.6 bits (179), Expect = 9e-13
Identities = 44/129 (34%), Positives = 66/129 (51%), Gaps = 5/129 (3%)
Query: 334 LSQGDIAQARKLYKCPA-CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLN 392
L +G + + +C A CG L +G +PG+P Y C W I PG I +
Sbjct: 734 LKEGSVVWNSAVLRCEAPCGGHLTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKIT 793
Query: 393 FTSMDLFKSRLCWYDYVEVRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNIL 452
F D FK+ + YD +EVRDG APL+G + G ++P+ L+ST + L++ F + +
Sbjct: 794 F---DRFKTEVN-YDTLEVRDGRTYSAPLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHS 849
Query: 453 GKGFFAAYE 461
GF YE
Sbjct: 850 DIGFQLRYE 858
Score = 70.5 bits (171), Expect = 8e-12
Identities = 35/111 (31%), Positives = 58/111 (52%), Gaps = 4/111 (3%)
Query: 351 CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVE 410
CG T+++ G +PGFP YPS C W+I++ G + F + + +DY+E
Sbjct: 1968 CGGTVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPN----HDYIE 2023
Query: 411 VRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYE 461
+R+G + + ++GRF G ++P L+ST V F S + GF Y+
Sbjct: 2024 IRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQ 2074
Score = 68.6 bits (166), Expect = 3e-11
Identities = 34/91 (37%), Positives = 48/91 (52%), Gaps = 4/91 (4%)
Query: 913 YPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGYDYMEAYDGYDSSAPRLGRFCGSGP 972
YP CDW + Y + L F F +E GYD++ YDG DS +P +G F GS
Sbjct: 1465 YPPGKECDWKVTVSPDYVIALVFNIFNLEP----GYDFLHIYDGRDSLSPLIGSFYGSQL 1520
Query: 973 LEEIYSAGDSLMIRFRTDDTINKKGFHARYT 1003
I S+ +SL + FR+D +++ GF YT
Sbjct: 1521 PGRIESSSNSLFLAFRSDASVSNAGFVIDYT 1551
Score = 67.8 bits (164), Expect = 5e-11
Identities = 34/110 (30%), Positives = 57/110 (51%), Gaps = 4/110 (3%)
Query: 351 CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVE 410
CG L +G +P +P YP C W+++V+P I L F +L YD++
Sbjct: 1445 CGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEPG----YDFLH 1500
Query: 411 VRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAY 460
+ DG +PL+G F G ++P + S+ + L++ FRS +++ GF Y
Sbjct: 1501 IYDGRDSLSPLIGSFYGSQLPGRIESSSNSLFLAFRSDASVSNAGFVIDY 1550
Score = 64.7 bits (156), Expect = 4e-10
Identities = 38/111 (34%), Positives = 55/111 (49%), Gaps = 4/111 (3%)
Query: 351 CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVE 410
CG L + G +PGFP Y + +CVW+I V G I + S F + W D +E
Sbjct: 1796 CGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVS---FVTEQNW-DSLE 1851
Query: 411 VRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYE 461
V DG +LG F G +P L ST ++L++ F S ++ GF Y+
Sbjct: 1852 VFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYK 1902
Score = 63.2 bits (152), Expect = 1e-09
Identities = 39/119 (32%), Positives = 56/119 (47%), Gaps = 8/119 (6%)
Query: 351 CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVE 410
C L G +PGFP GYP+Y++C W I+ +I L F S L + +D +
Sbjct: 26 CTFQLHGPNGTVESPGFPYGYPNYANCTWTITAEEQHRIQLVFQSFALEED----FDVLS 81
Query: 411 VRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEA----TCG 465
V DG + L R G ++P +VS + L + S + +GF A YE TCG
Sbjct: 82 VFDGPPQPENLRTRLTGFQLPATIVSAATTLSLRLISDYAVSAQGFHATYEVLPSHTCG 140
Score = 62.0 bits (149), Expect = 3e-09
Identities = 35/130 (26%), Positives = 65/130 (50%), Gaps = 5/130 (3%)
Query: 328 IGQRVRLSQGDIAQARKLYKCP-ACGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPG 386
+GQ+ Q + + K C +C +G +P +P Y ++ HCVW I P
Sbjct: 554 VGQKAITCQKNNQWSAKKPGCVFSCFFNFTSPSGVVLSPNYPEDYGNHLHCVWLILARPE 613
Query: 387 EKIVLNFTSMDLFKSRLCWYDYVEVRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFR 446
+I L F +D+ +D++ ++DG +AP+LG F G+++P + S+ +EF+
Sbjct: 614 SRIHLAFNDIDVEPQ----FDFLVIKDGATAEAPVLGTFSGNQLPSSITSSGHVARLEFQ 669
Query: 447 SSSNILGKGF 456
+ + +GF
Sbjct: 670 TDHSTGKRGF 679
Score = 58.5 bits (140), Expect = 3e-08
Identities = 39/130 (30%), Positives = 66/130 (50%), Gaps = 11/130 (8%)
Query: 343 RKLYKCPACGETLQDTTGNFSAPGFPNGYPSYSHCVWRI-SVTPGEKIVLNFTSMDLFKS 401
R + + C L+ +G ++P FP Y + +HCVW I ++ P + I L F DL +
Sbjct: 397 RPVCRARMCDAHLRGPSGIITSPNFPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLERG 456
Query: 402 RLCWYDYVEVRDG--YWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAA 459
YD + V DG + +L G +P+ +VST+ ++W+ F++ + GF A+
Sbjct: 457 ----YDTLTVGDGGQDGDQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKAS 512
Query: 460 YE----ATCG 465
YE +CG
Sbjct: 513 YEEIEQGSCG 522
Score = 57.0 bits (136), Expect = 9e-08
Identities = 39/122 (31%), Positives = 61/122 (50%), Gaps = 10/122 (8%)
Query: 345 LYKCPA-CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRL 403
L +C A CG ++ T G +P FP Y + C++ I PG+ I L + +L +
Sbjct: 1091 LPRCVAECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARAFELSEG-- 1148
Query: 404 CWYDYVEVRDGYWRKAPLLGRFC-GDKIPEPLVSTDSRLWVEFRSSSNILGKGF---FAA 459
D ++V DG A LLG F + + L ST S LW++F + + KGF F++
Sbjct: 1149 ---DVLKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENTSKGFELHFSS 1205
Query: 460 YE 461
+E
Sbjct: 1206 FE 1207
Score = 52.4 bits (124), Expect = 2e-06
Identities = 31/102 (30%), Positives = 51/102 (50%), Gaps = 5/102 (4%)
Query: 345 LYKCPA-CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRL 403
L KC CG + + G +PGFP+ Y S CVW I+V G + LN + + S
Sbjct: 2175 LPKCEVPCGGNITSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTEPSG- 2233
Query: 404 CWYDYVEVRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEF 445
D++ + DG + AP LG F + + S+ +++ ++F
Sbjct: 2234 ---DFITIWDGPQQTAPRLGVFTRSMAKKTVQSSSNQVLLKF 2272
Score = 49.3 bits (116), Expect = 2e-05
Identities = 35/116 (30%), Positives = 54/116 (46%), Gaps = 6/116 (5%)
Query: 348 CPACGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYD 407
CP E L D+TG + +P YP + C W + V P I L +++ F S YD
Sbjct: 2355 CPT-NELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISL---TVEYFLSEK-QYD 2409
Query: 408 YVEVRDGYWRKAPLLGRFCGD-KIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEA 462
E+ DG ++PLL G+ P + S+ + +++ + S KGF Y A
Sbjct: 2410 EFEIFDGPSGQSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRYSA 2465
Score = 47.4 bits (111), Expect = 7e-05
Identities = 27/94 (28%), Positives = 47/94 (50%), Gaps = 6/94 (6%)
Query: 342 ARKLYKCPA-CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFK 400
+R L C A CG +Q ++G +PGFP+ YP+ +C W I + G+ + F + L
Sbjct: 914 SRALPSCEALCGGFIQGSSGTILSPGFPDFYPNNLNCTWIIETSHGKGVFFTFHTFHLES 973
Query: 401 SRLCWYDYVEVRDGYWRKAPLLGRFCGDKIPEPL 434
+DY+ + + P L + G ++P P+
Sbjct: 974 G----HDYLLITENGSFTQP-LRQLTGSRLPAPI 1002
Score = 46.2 bits (108), Expect = 2e-04
Identities = 34/129 (26%), Positives = 57/129 (44%), Gaps = 6/129 (4%)
Query: 343 RKLYKCPA-CGETLQ-DTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFK 400
R L C A CG T++ + +G +PG+P Y +C+W I G I L+F D +
Sbjct: 1262 RPLPTCVAECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEE 1321
Query: 401 SRLCWYDYVEVRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAY 460
+D + + DG LL G +P+ L ST + + ++F + +GF +
Sbjct: 1322 V----HDVLRIWDGPVESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQF 1377
Query: 461 EATCGGDMN 469
+ N
Sbjct: 1378 SVSTATSCN 1386
Score = 42.0 bits (97), Expect = 0.003
Identities = 31/113 (27%), Positives = 54/113 (47%), Gaps = 6/113 (5%)
Query: 351 CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVE 410
CG + G +P +P Y S C++ ++V P + +V F F + L D VE
Sbjct: 1619 CGGQYVGSDGVVLSPNYPQNYTSGQICLYFVTV-PKDYVV--FGQFAFFHTAL--NDVVE 1673
Query: 411 VRDGYWRKAPLLGRFCGDKIPEPL-VSTDSRLWVEFRSSSNILGKGFFAAYEA 462
V DG+ + + LL G E L ++T +++ ++F + +GF Y+A
Sbjct: 1674 VHDGHSQHSRLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPARGFHFVYQA 1726
>gi|73623026 mannan-binding lectin serine protease 1 isoform 3 [Homo
sapiens]
Length = 380
Score = 170 bits (431), Expect = 5e-42
Identities = 100/287 (34%), Positives = 152/287 (52%), Gaps = 25/287 (8%)
Query: 467 DMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDYLEVRD 526
++N GQIQSP YPD Y E W ITV +GF + L F F +E C YDY++V
Sbjct: 23 ELNNMFGQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYFMHFNLESSYLCEYDYVKVE- 81
Query: 527 GPTEESALIGHFCGYEK--------PEDVKSSSNRLWMKFVSDGSINK--AGFAANFFK- 575
E ++ FCG E E V S + + + F SD S + GF A++
Sbjct: 82 ---TEDQVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTGFDAHYMAV 138
Query: 576 EVDECS--WPDHGGCEHRCVNTLGSYKCACDPGYELAADKKMCEVACG-GFITKLNGTIT 632
+VDEC + C+H C N +G Y C+C GY L D + C V C T+ G IT
Sbjct: 139 DVDECKEREDEELSCDHYCHNYIGGYYCSCRFGYILHTDNRTCRVECSDNLFTQRTGVIT 198
Query: 633 SPGWPKEYPTNKNCVWQVVAPAQYRISLQFE-VFELEGND--VCKYDFVEVRSGLSPDAK 689
SP +P YP + C++ + + ++LQFE +F++E + C YD+++++ G K
Sbjct: 199 SPDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEVPCPYDYIKIKVG----PK 254
Query: 690 LHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDEC 736
+ G FCG + PE I++QS+++ + F SDN+ RG+R + + +EC
Sbjct: 255 VLGPFCGEKAPEPISTQSHSVLILFHSDNSGENRGWRLSYRAAGNEC 301
Score = 168 bits (425), Expect = 3e-41
Identities = 94/276 (34%), Positives = 144/276 (52%), Gaps = 25/276 (9%)
Query: 624 ITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVEVRSG 683
+ + G I SPG+P YP++ W + P +RI L F F LE + +C+YD+V+V +
Sbjct: 24 LNNMFGQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYFMHFNLESSYLCEYDYVKVET- 82
Query: 684 LSPDAKLHGRFCGSETP--------EVITSQSNNMRVEFKSDNTVSKR--GFRAHFFS-D 732
+ ++ FCG ET EV+ S + M + F+SD + +R GF AH+ + D
Sbjct: 83 ---EDQVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTGFDAHYMAVD 139
Query: 733 KDECAK---DNGGCQHECVNTFGSYLCRCRNGYWLHENGHDCKEAGCAHKISSVEGTLAS 789
DEC + + C H C N G Y C CR GY LH + C+ + + G + S
Sbjct: 140 VDECKEREDEELSCDHYCHNYIGGYYCSCRFGYILHTDNRTCRVECSDNLFTQRTGVITS 199
Query: 790 PNWPDKYPSRRECTWNISSTAGHRVKLTFNE-FEIEQHQE--CAYDHLEMYDGPDSLAPI 846
P++P+ YP EC + I G V L F + F+IE H E C YD++++ GP +
Sbjct: 200 PDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEVPCPYDYIKIKVGP----KV 255
Query: 847 LGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQ 882
LG FCG K P+P S+ + F+SD S + +G++
Sbjct: 256 LGPFCGEKAPEPISTQSHSVLILFHSDNSGENRGWR 291
Score = 110 bits (276), Expect = 5e-24
Identities = 96/333 (28%), Positives = 143/333 (42%), Gaps = 73/333 (21%)
Query: 345 LYKCPACGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLC 404
L K A L + G +PG+P+ YPS S W I+V G +I L F +L S LC
Sbjct: 14 LSKASAHTVELNNMFGQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYFMHFNLESSYLC 73
Query: 405 WYDYVEVRDGYWRKAPLLGRFCG------DKIP--EPLVSTDSRLWVEFRS--SSNILGK 454
YDYV+V + +L FCG ++ P E ++S S + + FRS S+
Sbjct: 74 EYDYVKVE----TEDQVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFT 129
Query: 455 GFFAAYEA------------------------------------------TCGGDMNKD- 471
GF A Y A TC + + +
Sbjct: 130 GFDAHYMAVDVDECKEREDEELSCDHYCHNYIGGYYCSCRFGYILHTDNRTCRVECSDNL 189
Query: 472 ----AGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQ-AFEIERHDS--CAYDYLEV 524
G I SP++P+ Y S EC++ I + EGF V L F+ F+IE H C YDY+++
Sbjct: 190 FTQRTGVITSPDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEVPCPYDYIKI 249
Query: 525 RDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDEC---S 581
+ GP ++G FCG + PE + + S+ + + F SD S G+ ++ +EC
Sbjct: 250 KVGP----KVLGPFCGEKAPEPISTQSHSVLILFHSDNSGENRGWRLSYRAAGNECPELQ 305
Query: 582 WPDHGGCEHRCVNTL--GSYKCACDPGYELAAD 612
P HG E +CD GY++ D
Sbjct: 306 PPVHGKIEPSQAKYFFKDQVLVSCDTGYKVLKD 338
Score = 95.1 bits (235), Expect = 3e-19
Identities = 76/281 (27%), Positives = 120/281 (42%), Gaps = 66/281 (23%)
Query: 779 KISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMYD 838
+++++ G + SP +PD YPS E TWNI+ G R+KL F F +E C YD++++
Sbjct: 23 ELNNMFGQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYFMHFNLESSYLCEYDYVKV-- 80
Query: 839 GPDSLAPILGRFCGSKKPDP--------TVASGSSMFLRFYSDASVQRK------GFQAV 884
++ +L FCG + D ++ GS M + F SD S + + + AV
Sbjct: 81 --ETEDQVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTGFDAHYMAV 138
Query: 885 HSTECGGRLKAEVQTKE--------LYSHAQFG--------------------------- 909
EC R E+ Y +FG
Sbjct: 139 DVDECKEREDEELSCDHYCHNYIGGYYCSCRFGYILHTDNRTCRVECSDNLFTQRTGVIT 198
Query: 910 ----DNNYPSEARCDWVIVAEDGYGVELTFR-TFEVEE--EADCGYDYMEAYDGYDSSAP 962
N YP + C + I E+G+ V L F F++E+ E C YDY++ G P
Sbjct: 199 SPDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEVPCPYDYIKIKVG-----P 253
Query: 963 R-LGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARY 1002
+ LG FCG E I + S++I F +D++ +G+ Y
Sbjct: 254 KVLGPFCGEKAPEPISTQSHSVLILFHSDNSGENRGWRLSY 294
Score = 48.9 bits (115), Expect = 2e-05
Identities = 38/131 (29%), Positives = 58/131 (44%), Gaps = 23/131 (17%)
Query: 889 CGGRLKAEVQTKELYSHAQFGD-------NNYPSEARCDWVIVAEDGYGVELTFRTFEVE 941
C KA T EL + FG ++YPS++ W I DG+ ++L F F +E
Sbjct: 11 CFSLSKASAHTVELNN--MFGQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYFMHFNLE 68
Query: 942 EEADCGYDYMEAYDGYDSSAPRLGRFCG--------SGPLEEIYSAGDSLMIRFRTDDTI 993
C YDY++ ++ L FCG + E + S G + I FR+D +
Sbjct: 69 SSYLCEYDYVKV----ETEDQVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSN 124
Query: 994 NKK--GFHARY 1002
++ GF A Y
Sbjct: 125 EERFTGFDAHY 135
>gi|21264359 mannan-binding lectin serine protease 1 isoform 2
precursor [Homo sapiens]
Length = 728
Score = 170 bits (431), Expect = 5e-42
Identities = 100/287 (34%), Positives = 152/287 (52%), Gaps = 25/287 (8%)
Query: 467 DMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDYLEVRD 526
++N GQIQSP YPD Y E W ITV +GF + L F F +E C YDY++V
Sbjct: 23 ELNNMFGQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYFMHFNLESSYLCEYDYVKVE- 81
Query: 527 GPTEESALIGHFCGYEK--------PEDVKSSSNRLWMKFVSDGSINK--AGFAANFFK- 575
E ++ FCG E E V S + + + F SD S + GF A++
Sbjct: 82 ---TEDQVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTGFDAHYMAV 138
Query: 576 EVDECS--WPDHGGCEHRCVNTLGSYKCACDPGYELAADKKMCEVACG-GFITKLNGTIT 632
+VDEC + C+H C N +G Y C+C GY L D + C V C T+ G IT
Sbjct: 139 DVDECKEREDEELSCDHYCHNYIGGYYCSCRFGYILHTDNRTCRVECSDNLFTQRTGVIT 198
Query: 633 SPGWPKEYPTNKNCVWQVVAPAQYRISLQFE-VFELEGND--VCKYDFVEVRSGLSPDAK 689
SP +P YP + C++ + + ++LQFE +F++E + C YD+++++ G K
Sbjct: 199 SPDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEVPCPYDYIKIKVG----PK 254
Query: 690 LHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDEC 736
+ G FCG + PE I++QS+++ + F SDN+ RG+R + + +EC
Sbjct: 255 VLGPFCGEKAPEPISTQSHSVLILFHSDNSGENRGWRLSYRAAGNEC 301
Score = 168 bits (425), Expect = 3e-41
Identities = 94/276 (34%), Positives = 144/276 (52%), Gaps = 25/276 (9%)
Query: 624 ITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVEVRSG 683
+ + G I SPG+P YP++ W + P +RI L F F LE + +C+YD+V+V +
Sbjct: 24 LNNMFGQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYFMHFNLESSYLCEYDYVKVET- 82
Query: 684 LSPDAKLHGRFCGSETP--------EVITSQSNNMRVEFKSDNTVSKR--GFRAHFFS-D 732
+ ++ FCG ET EV+ S + M + F+SD + +R GF AH+ + D
Sbjct: 83 ---EDQVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTGFDAHYMAVD 139
Query: 733 KDECAK---DNGGCQHECVNTFGSYLCRCRNGYWLHENGHDCKEAGCAHKISSVEGTLAS 789
DEC + + C H C N G Y C CR GY LH + C+ + + G + S
Sbjct: 140 VDECKEREDEELSCDHYCHNYIGGYYCSCRFGYILHTDNRTCRVECSDNLFTQRTGVITS 199
Query: 790 PNWPDKYPSRRECTWNISSTAGHRVKLTFNE-FEIEQHQE--CAYDHLEMYDGPDSLAPI 846
P++P+ YP EC + I G V L F + F+IE H E C YD++++ GP +
Sbjct: 200 PDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEVPCPYDYIKIKVGP----KV 255
Query: 847 LGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQ 882
LG FCG K P+P S+ + F+SD S + +G++
Sbjct: 256 LGPFCGEKAPEPISTQSHSVLILFHSDNSGENRGWR 291
Score = 110 bits (276), Expect = 5e-24
Identities = 96/333 (28%), Positives = 143/333 (42%), Gaps = 73/333 (21%)
Query: 345 LYKCPACGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLC 404
L K A L + G +PG+P+ YPS S W I+V G +I L F +L S LC
Sbjct: 14 LSKASAHTVELNNMFGQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYFMHFNLESSYLC 73
Query: 405 WYDYVEVRDGYWRKAPLLGRFCG------DKIP--EPLVSTDSRLWVEFRS--SSNILGK 454
YDYV+V + +L FCG ++ P E ++S S + + FRS S+
Sbjct: 74 EYDYVKVE----TEDQVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFT 129
Query: 455 GFFAAYEA------------------------------------------TCGGDMNKD- 471
GF A Y A TC + + +
Sbjct: 130 GFDAHYMAVDVDECKEREDEELSCDHYCHNYIGGYYCSCRFGYILHTDNRTCRVECSDNL 189
Query: 472 ----AGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQ-AFEIERHDS--CAYDYLEV 524
G I SP++P+ Y S EC++ I + EGF V L F+ F+IE H C YDY+++
Sbjct: 190 FTQRTGVITSPDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEVPCPYDYIKI 249
Query: 525 RDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDEC---S 581
+ GP ++G FCG + PE + + S+ + + F SD S G+ ++ +EC
Sbjct: 250 KVGP----KVLGPFCGEKAPEPISTQSHSVLILFHSDNSGENRGWRLSYRAAGNECPELQ 305
Query: 582 WPDHGGCEHRCVNTL--GSYKCACDPGYELAAD 612
P HG E +CD GY++ D
Sbjct: 306 PPVHGKIEPSQAKYFFKDQVLVSCDTGYKVLKD 338
Score = 95.1 bits (235), Expect = 3e-19
Identities = 76/281 (27%), Positives = 120/281 (42%), Gaps = 66/281 (23%)
Query: 779 KISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMYD 838
+++++ G + SP +PD YPS E TWNI+ G R+KL F F +E C YD++++
Sbjct: 23 ELNNMFGQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYFMHFNLESSYLCEYDYVKV-- 80
Query: 839 GPDSLAPILGRFCGSKKPDP--------TVASGSSMFLRFYSDASVQRK------GFQAV 884
++ +L FCG + D ++ GS M + F SD S + + + AV
Sbjct: 81 --ETEDQVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTGFDAHYMAV 138
Query: 885 HSTECGGRLKAEVQTKE--------LYSHAQFG--------------------------- 909
EC R E+ Y +FG
Sbjct: 139 DVDECKEREDEELSCDHYCHNYIGGYYCSCRFGYILHTDNRTCRVECSDNLFTQRTGVIT 198
Query: 910 ----DNNYPSEARCDWVIVAEDGYGVELTFR-TFEVEE--EADCGYDYMEAYDGYDSSAP 962
N YP + C + I E+G+ V L F F++E+ E C YDY++ G P
Sbjct: 199 SPDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEVPCPYDYIKIKVG-----P 253
Query: 963 R-LGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARY 1002
+ LG FCG E I + S++I F +D++ +G+ Y
Sbjct: 254 KVLGPFCGEKAPEPISTQSHSVLILFHSDNSGENRGWRLSY 294
Score = 48.9 bits (115), Expect = 2e-05
Identities = 38/131 (29%), Positives = 58/131 (44%), Gaps = 23/131 (17%)
Query: 889 CGGRLKAEVQTKELYSHAQFGD-------NNYPSEARCDWVIVAEDGYGVELTFRTFEVE 941
C KA T EL + FG ++YPS++ W I DG+ ++L F F +E
Sbjct: 11 CFSLSKASAHTVELNN--MFGQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYFMHFNLE 68
Query: 942 EEADCGYDYMEAYDGYDSSAPRLGRFCG--------SGPLEEIYSAGDSLMIRFRTDDTI 993
C YDY++ ++ L FCG + E + S G + I FR+D +
Sbjct: 69 SSYLCEYDYVKV----ETEDQVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSN 124
Query: 994 NKK--GFHARY 1002
++ GF A Y
Sbjct: 125 EERFTGFDAHY 135
>gi|21264357 mannan-binding lectin serine protease 1 isoform 1
precursor [Homo sapiens]
Length = 699
Score = 170 bits (431), Expect = 5e-42
Identities = 100/287 (34%), Positives = 152/287 (52%), Gaps = 25/287 (8%)
Query: 467 DMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDYLEVRD 526
++N GQIQSP YPD Y E W ITV +GF + L F F +E C YDY++V
Sbjct: 23 ELNNMFGQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYFMHFNLESSYLCEYDYVKVE- 81
Query: 527 GPTEESALIGHFCGYEK--------PEDVKSSSNRLWMKFVSDGSINK--AGFAANFFK- 575
E ++ FCG E E V S + + + F SD S + GF A++
Sbjct: 82 ---TEDQVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTGFDAHYMAV 138
Query: 576 EVDECS--WPDHGGCEHRCVNTLGSYKCACDPGYELAADKKMCEVACG-GFITKLNGTIT 632
+VDEC + C+H C N +G Y C+C GY L D + C V C T+ G IT
Sbjct: 139 DVDECKEREDEELSCDHYCHNYIGGYYCSCRFGYILHTDNRTCRVECSDNLFTQRTGVIT 198
Query: 633 SPGWPKEYPTNKNCVWQVVAPAQYRISLQFE-VFELEGND--VCKYDFVEVRSGLSPDAK 689
SP +P YP + C++ + + ++LQFE +F++E + C YD+++++ G K
Sbjct: 199 SPDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEVPCPYDYIKIKVG----PK 254
Query: 690 LHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDEC 736
+ G FCG + PE I++QS+++ + F SDN+ RG+R + + +EC
Sbjct: 255 VLGPFCGEKAPEPISTQSHSVLILFHSDNSGENRGWRLSYRAAGNEC 301
Score = 168 bits (425), Expect = 3e-41
Identities = 94/276 (34%), Positives = 144/276 (52%), Gaps = 25/276 (9%)
Query: 624 ITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVEVRSG 683
+ + G I SPG+P YP++ W + P +RI L F F LE + +C+YD+V+V +
Sbjct: 24 LNNMFGQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYFMHFNLESSYLCEYDYVKVET- 82
Query: 684 LSPDAKLHGRFCGSETP--------EVITSQSNNMRVEFKSDNTVSKR--GFRAHFFS-D 732
+ ++ FCG ET EV+ S + M + F+SD + +R GF AH+ + D
Sbjct: 83 ---EDQVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTGFDAHYMAVD 139
Query: 733 KDECAK---DNGGCQHECVNTFGSYLCRCRNGYWLHENGHDCKEAGCAHKISSVEGTLAS 789
DEC + + C H C N G Y C CR GY LH + C+ + + G + S
Sbjct: 140 VDECKEREDEELSCDHYCHNYIGGYYCSCRFGYILHTDNRTCRVECSDNLFTQRTGVITS 199
Query: 790 PNWPDKYPSRRECTWNISSTAGHRVKLTFNE-FEIEQHQE--CAYDHLEMYDGPDSLAPI 846
P++P+ YP EC + I G V L F + F+IE H E C YD++++ GP +
Sbjct: 200 PDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEVPCPYDYIKIKVGP----KV 255
Query: 847 LGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQ 882
LG FCG K P+P S+ + F+SD S + +G++
Sbjct: 256 LGPFCGEKAPEPISTQSHSVLILFHSDNSGENRGWR 291
Score = 110 bits (276), Expect = 5e-24
Identities = 96/333 (28%), Positives = 143/333 (42%), Gaps = 73/333 (21%)
Query: 345 LYKCPACGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLC 404
L K A L + G +PG+P+ YPS S W I+V G +I L F +L S LC
Sbjct: 14 LSKASAHTVELNNMFGQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYFMHFNLESSYLC 73
Query: 405 WYDYVEVRDGYWRKAPLLGRFCG------DKIP--EPLVSTDSRLWVEFRS--SSNILGK 454
YDYV+V + +L FCG ++ P E ++S S + + FRS S+
Sbjct: 74 EYDYVKVE----TEDQVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFT 129
Query: 455 GFFAAYEA------------------------------------------TCGGDMNKD- 471
GF A Y A TC + + +
Sbjct: 130 GFDAHYMAVDVDECKEREDEELSCDHYCHNYIGGYYCSCRFGYILHTDNRTCRVECSDNL 189
Query: 472 ----AGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQ-AFEIERHDS--CAYDYLEV 524
G I SP++P+ Y S EC++ I + EGF V L F+ F+IE H C YDY+++
Sbjct: 190 FTQRTGVITSPDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEVPCPYDYIKI 249
Query: 525 RDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDEC---S 581
+ GP ++G FCG + PE + + S+ + + F SD S G+ ++ +EC
Sbjct: 250 KVGP----KVLGPFCGEKAPEPISTQSHSVLILFHSDNSGENRGWRLSYRAAGNECPELQ 305
Query: 582 WPDHGGCEHRCVNTL--GSYKCACDPGYELAAD 612
P HG E +CD GY++ D
Sbjct: 306 PPVHGKIEPSQAKYFFKDQVLVSCDTGYKVLKD 338
Score = 95.1 bits (235), Expect = 3e-19
Identities = 76/281 (27%), Positives = 120/281 (42%), Gaps = 66/281 (23%)
Query: 779 KISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMYD 838
+++++ G + SP +PD YPS E TWNI+ G R+KL F F +E C YD++++
Sbjct: 23 ELNNMFGQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYFMHFNLESSYLCEYDYVKV-- 80
Query: 839 GPDSLAPILGRFCGSKKPDP--------TVASGSSMFLRFYSDASVQRK------GFQAV 884
++ +L FCG + D ++ GS M + F SD S + + + AV
Sbjct: 81 --ETEDQVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTGFDAHYMAV 138
Query: 885 HSTECGGRLKAEVQTKE--------LYSHAQFG--------------------------- 909
EC R E+ Y +FG
Sbjct: 139 DVDECKEREDEELSCDHYCHNYIGGYYCSCRFGYILHTDNRTCRVECSDNLFTQRTGVIT 198
Query: 910 ----DNNYPSEARCDWVIVAEDGYGVELTFR-TFEVEE--EADCGYDYMEAYDGYDSSAP 962
N YP + C + I E+G+ V L F F++E+ E C YDY++ G P
Sbjct: 199 SPDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEVPCPYDYIKIKVG-----P 253
Query: 963 R-LGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARY 1002
+ LG FCG E I + S++I F +D++ +G+ Y
Sbjct: 254 KVLGPFCGEKAPEPISTQSHSVLILFHSDNSGENRGWRLSY 294
Score = 48.9 bits (115), Expect = 2e-05
Identities = 38/131 (29%), Positives = 58/131 (44%), Gaps = 23/131 (17%)
Query: 889 CGGRLKAEVQTKELYSHAQFGD-------NNYPSEARCDWVIVAEDGYGVELTFRTFEVE 941
C KA T EL + FG ++YPS++ W I DG+ ++L F F +E
Sbjct: 11 CFSLSKASAHTVELNN--MFGQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYFMHFNLE 68
Query: 942 EEADCGYDYMEAYDGYDSSAPRLGRFCG--------SGPLEEIYSAGDSLMIRFRTDDTI 993
C YDY++ ++ L FCG + E + S G + I FR+D +
Sbjct: 69 SSYLCEYDYVKV----ETEDQVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSN 124
Query: 994 NKK--GFHARY 1002
++ GF A Y
Sbjct: 125 EERFTGFDAHY 135
>gi|157653329 procollagen C-endopeptidase enhancer [Homo sapiens]
Length = 449
Score = 169 bits (427), Expect = 2e-41
Identities = 94/281 (33%), Positives = 144/281 (51%), Gaps = 36/281 (12%)
Query: 464 CGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDYLE 523
CGGD+ ++G + S +P+ Y P+KEC+W ITV EG V L+F+ F++E H +C YD LE
Sbjct: 37 CGGDVKGESGYVASEGFPNLYPPNKECIWTITVPEGQTVSLSFRVFDLELHPACRYDALE 96
Query: 524 VRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECSWP 583
V G +G FCG +P + + N++ ++ +D GF + S
Sbjct: 97 VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTTDEGTGGRGFLLWY-------SGR 149
Query: 584 DHGGCEHRCVNTLGSYKCACDPGYELAADKKMCEVACGGFITKLNGTITSPGWPK-EYPT 642
G EH+ CGG + K GT+T+P WP+ +YP
Sbjct: 150 ATSGTEHQF---------------------------CGGRLEKAQGTLTTPNWPESDYPP 182
Query: 643 NKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVEVRSG-LSPDAKLHGRFCGSETPE 701
+C W ++AP I+L FE F+LE + C+YD V V +G +S D++ G+FCG P
Sbjct: 183 GISCSWHIIAPPDQVIALTFEKFDLEPDTYCRYDSVSVFNGAVSDDSRRLGKFCGDAVPG 242
Query: 702 VITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECAKDNGG 742
I+S+ N + V+F SD +V+ GF A + + AK+ G
Sbjct: 243 SISSEGNELLVQFVSDLSVTADGFSASYKTLPRGTAKEGQG 283
Score = 147 bits (370), Expect = 6e-35
Identities = 81/277 (29%), Positives = 128/277 (46%), Gaps = 36/277 (12%)
Query: 620 CGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVE 679
CGG + +G + S G+P YP NK C+W + P +SL F VF+LE + C+YD +E
Sbjct: 37 CGGDVKGESGYVASEGFPNLYPPNKECIWTITVPEGQTVSLSFRVFDLELHPACRYDALE 96
Query: 680 VRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECAKD 739
V +G + GRFCG+ P + + N + + +D RGF + +
Sbjct: 97 VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTTDEGTGGRGFLLWY------SGRA 150
Query: 740 NGGCQHECVNTFGSYLCRCRNGYWLHENGHDCKEAGCAHKISSVEGTLASPNWPDK-YPS 798
G +H+ C ++ +GTL +PNWP+ YP
Sbjct: 151 TSGTEHQF----------------------------CGGRLEKAQGTLTTPNWPESDYPP 182
Query: 799 RRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMYDGPDSL-APILGRFCGSKKPD 857
C+W+I + + LTF +F++E C YD + +++G S + LG+FCG P
Sbjct: 183 GISCSWHIIAPPDQVIALTFEKFDLEPDTYCRYDSVSVFNGAVSDDSRRLGKFCGDAVPG 242
Query: 858 PTVASGSSMFLRFYSDASVQRKGFQAVHSTECGGRLK 894
+ G+ + ++F SD SV GF A + T G K
Sbjct: 243 SISSEGNELLVQFVSDLSVTADGFSASYKTLPRGTAK 279
Score = 146 bits (369), Expect = 8e-35
Identities = 79/237 (33%), Positives = 123/237 (51%), Gaps = 13/237 (5%)
Query: 776 CAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLE 835
C + G +AS +P+ YP +EC W I+ G V L+F F++E H C YD LE
Sbjct: 37 CGGDVKGESGYVASEGFPNLYPPNKECIWTITVPEGQTVSLSFRVFDLELHPACRYDALE 96
Query: 836 MYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGF------QAVHSTE- 888
++ G + LGRFCG+ +P P VA G+ + LR +D +GF +A TE
Sbjct: 97 VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTTDEGTGGRGFLLWYSGRATSGTEH 156
Query: 889 --CGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADC 946
CGGRL+ + + + + +++YP C W I+A + LTF F++E + C
Sbjct: 157 QFCGGRLE---KAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVIALTFEKFDLEPDTYC 213
Query: 947 GYDYMEAYDG-YDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARY 1002
YD + ++G + RLG+FCG I S G+ L+++F +D ++ GF A Y
Sbjct: 214 RYDSVSVFNGAVSDDSRRLGKFCGDAVPGSISSEGNELLVQFVSDLSVTADGFSASY 270
Score = 145 bits (366), Expect = 2e-34
Identities = 79/234 (33%), Positives = 119/234 (50%), Gaps = 11/234 (4%)
Query: 351 CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVE 410
CG ++ +G ++ GFPN YP C+W I+V G+ + L+F DL C YD +E
Sbjct: 37 CGGDVKGESGYVASEGFPNLYPPNKECIWTITVPEGQTVSLSFRVFDLELHPACRYDALE 96
Query: 411 VRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEAT------- 463
V G LGRFCG P PLV+ +++ + + G+GF Y
Sbjct: 97 VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTTDEGTGGRGFLLWYSGRATSGTEH 156
Query: 464 --CGGDMNKDAGQIQSPNYPD-DYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYD 520
CGG + K G + +PN+P+ DY P C W I + LTF+ F++E C YD
Sbjct: 157 QFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVIALTFEKFDLEPDTYCRYD 216
Query: 521 YLEVRDGP-TEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANF 573
+ V +G +++S +G FCG P + S N L ++FVSD S+ GF+A++
Sbjct: 217 SVSVFNGAVSDDSRRLGKFCGDAVPGSISSEGNELLVQFVSDLSVTADGFSASY 270
Score = 73.9 bits (180), Expect = 7e-13
Identities = 39/115 (33%), Positives = 58/115 (50%), Gaps = 4/115 (3%)
Query: 889 CGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGY 948
CGG +K E Y ++ N YP C W I +G V L+FR F++E C Y
Sbjct: 37 CGGDVKGESG----YVASEGFPNLYPPNKECIWTITVPEGQTVSLSFRVFDLELHPACRY 92
Query: 949 DYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARYT 1003
D +E + G +S RLGRFCG+ + + G+ + +R TD+ +GF Y+
Sbjct: 93 DALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTTDEGTGGRGFLLWYS 147
Score = 70.5 bits (171), Expect = 8e-12
Identities = 41/125 (32%), Positives = 57/125 (45%), Gaps = 2/125 (1%)
Query: 351 CGETLQDTTGNFSAPGFPNG-YPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYV 409
CG L+ G + P +P YP C W I P + I L F DL C YD V
Sbjct: 159 CGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVIALTFEKFDLEPDTYCRYDSV 218
Query: 410 EVRDGYWRK-APLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEATCGGDM 468
V +G + LG+FCGD +P + S + L V+F S ++ GF A+Y+ G
Sbjct: 219 SVFNGAVSDDSRRLGKFCGDAVPGSISSEGNELLVQFVSDLSVTADGFSASYKTLPRGTA 278
Query: 469 NKDAG 473
+ G
Sbjct: 279 KEGQG 283
>gi|13899255 membrane frizzled-related protein [Homo sapiens]
Length = 579
Score = 166 bits (420), Expect = 1e-40
Identities = 106/326 (32%), Positives = 155/326 (47%), Gaps = 31/326 (9%)
Query: 461 EATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYD 520
++TCGG ++ G SPNYPD Y P+ CVW I V+ + L +A IE SC +D
Sbjct: 141 QSTCGGLLSGPRGFFSSPNYPDPYPPNTHCVWHIQVATDHAIQLKIEALSIESVASCLFD 200
Query: 521 YLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDEC 580
LE+ P E L+ CG P + ++++ L + FVSD S+ GF A + +
Sbjct: 201 RLEL--SPEPEGPLL-RVCGRVPPPTLNTNASHLLVVFVSDSSVEGFGFHAWY-----QA 252
Query: 581 SWPDHGGCEH---RCVNTLGSYKCACDPGYELAA---DKKMCEV---ACGGFITKLNGTI 631
P G C H RC + + G+ A D+ C CGG +T L GT
Sbjct: 253 MAPGRGSCAHDEFRCDQLICLLPDSVCDGFANCADGSDETNCSAKFSGCGGNLTGLQGTF 312
Query: 632 TSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVEVRSGLSPDA-KL 690
++P + ++YP C W + PA + I LQF F LE D CK+D+VEV S A L
Sbjct: 313 STPSYLQQYPHQLLCTWHISVPAGHSIELQFHNFSLEAQDECKFDYVEVYETSSSGAFSL 372
Query: 691 HGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRA---HFFSDKDECAKDNGGCQHEC 747
GRFCG+E P + S + + V F++D+ +S GF A F + ++ C CQ
Sbjct: 373 LGRFCGAEPPPHLVSSHHELAVLFRTDHGISSGGFSATYLAFNATENPCGPSELSCQ--- 429
Query: 748 VNTFGSYLCRCRNGYWLHENGHDCKE 773
C+ W+ + DC +
Sbjct: 430 -------AGGCKGVQWMCDMWRDCTD 448
Score = 149 bits (377), Expect = 1e-35
Identities = 83/274 (30%), Positives = 141/274 (51%), Gaps = 14/274 (5%)
Query: 620 CGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVE 679
CGG ++ G +SP +P YP N +CVW + + I L+ E +E C +D +E
Sbjct: 144 CGGLLSGPRGFFSSPNYPDPYPPNTHCVWHIQVATDHAIQLKIEALSIESVASCLFDRLE 203
Query: 680 VRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFS---DKDEC 736
+ P+ L R CG P + + ++++ V F SD++V GF A + + + C
Sbjct: 204 LSP--EPEGPLL-RVCGRVPPPTLNTNASHLLVVFVSDSSVEGFGFHAWYQAMAPGRGSC 260
Query: 737 AKDNGGCQHECVNTFGSYLC----RCRNGYWLHENGHDCKEAGCAHKISSVEGTLASPNW 792
A D C + + +C C +G E K +GC ++ ++GT ++P++
Sbjct: 261 AHDEFRCD-QLICLLPDSVCDGFANCADGS--DETNCSAKFSGCGGNLTGLQGTFSTPSY 317
Query: 793 PDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMYDGPDSLA-PILGRFC 851
+YP + CTW+IS AGH ++L F+ F +E EC +D++E+Y+ S A +LGRFC
Sbjct: 318 LQQYPHQLLCTWHISVPAGHSIELQFHNFSLEAQDECKFDYVEVYETSSSGAFSLLGRFC 377
Query: 852 GSKKPDPTVASGSSMFLRFYSDASVQRKGFQAVH 885
G++ P V+S + + F +D + GF A +
Sbjct: 378 GAEPPPHLVSSHHELAVLFRTDHGISSGGFSATY 411
Score = 122 bits (306), Expect = 2e-27
Identities = 80/278 (28%), Positives = 114/278 (41%), Gaps = 55/278 (19%)
Query: 773 EAGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYD 832
++ C +S G +SPN+PD YP C W+I H ++L IE C +D
Sbjct: 141 QSTCGGLLSGPRGFFSSPNYPDPYPPNTHCVWHIQVATDHAIQLKIEALSIESVASCLFD 200
Query: 833 HLEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQAVHS------ 886
LE+ P+ P+L R CG P + S + + F SD+SV+ GF A +
Sbjct: 201 RLEL--SPEPEGPLL-RVCGRVPPPTLNTNASHLLVVFVSDSSVEGFGFHAWYQAMAPGR 257
Query: 887 -----------------------------------------TECGGRLKAEVQTKELYSH 905
+ CGG L T S+
Sbjct: 258 GSCAHDEFRCDQLICLLPDSVCDGFANCADGSDETNCSAKFSGCGGNLTGLQGTFSTPSY 317
Query: 906 AQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGYDYMEAYDGYDSSA-PRL 964
Q YP + C W I G+ +EL F F +E + +C +DY+E Y+ S A L
Sbjct: 318 LQ----QYPHQLLCTWHISVPAGHSIELQFHNFSLEAQDECKFDYVEVYETSSSGAFSLL 373
Query: 965 GRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARY 1002
GRFCG+ P + S+ L + FRTD I+ GF A Y
Sbjct: 374 GRFCGAEPPPHLVSSHHELAVLFRTDHGISSGGFSATY 411
Score = 120 bits (301), Expect = 6e-27
Identities = 83/290 (28%), Positives = 125/290 (43%), Gaps = 55/290 (18%)
Query: 351 CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVE 410
CG L G FS+P +P+ YP +HCVW I V I L ++ + C +D +E
Sbjct: 144 CGGLLSGPRGFFSSPNYPDPYPPNTHCVWHIQVATDHAIQLKIEALSIESVASCLFDRLE 203
Query: 411 VRDGYWRKAPLLGRFCGDKIPEPLVSTD-SRLWVEFRSSSNILGKGFFAAYEAT------ 463
+ + PLL R CG ++P P ++T+ S L V F S S++ G GF A Y+A
Sbjct: 204 LSPE--PEGPLL-RVCG-RVPPPTLNTNASHLLVVFVSDSSVEGFGFHAWYQAMAPGRGS 259
Query: 464 -----------------------------------------CGGDMNKDAGQIQSPNYPD 482
CGG++ G +P+Y
Sbjct: 260 CAHDEFRCDQLICLLPDSVCDGFANCADGSDETNCSAKFSGCGGNLTGLQGTFSTPSYLQ 319
Query: 483 DYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDYLEVRDGPTEES-ALIGHFCGY 541
Y C W I+V G + L F F +E D C +DY+EV + + + +L+G FCG
Sbjct: 320 QYPHQLLCTWHISVPAGHSIELQFHNFSLEAQDECKFDYVEVYETSSSGAFSLLGRFCGA 379
Query: 542 EKPEDVKSSSNRLWMKFVSDGSINKAGFAANF--FKEVDECSWPDHGGCE 589
E P + SS + L + F +D I+ GF+A + F + P C+
Sbjct: 380 EPPPHLVSSHHELAVLFRTDHGISSGGFSATYLAFNATENPCGPSELSCQ 429
Score = 76.6 bits (187), Expect = 1e-13
Identities = 48/117 (41%), Positives = 55/117 (47%), Gaps = 1/117 (0%)
Query: 347 KCPACGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWY 406
K CG L G FS P + YP C W ISV G I L F + L C +
Sbjct: 297 KFSGCGGNLTGLQGTFSTPSYLQQYPHQLLCTWHISVPAGHSIELQFHNFSLEAQDECKF 356
Query: 407 DYVEVRDGYWRKA-PLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEA 462
DYVEV + A LLGRFCG + P LVS+ L V FR+ I GF A Y A
Sbjct: 357 DYVEVYETSSSGAFSLLGRFCGAEPPPHLVSSHHELAVLFRTDHGISSGGFSATYLA 413
Score = 48.9 bits (115), Expect = 2e-05
Identities = 33/126 (26%), Positives = 51/126 (40%), Gaps = 7/126 (5%)
Query: 877 QRKGFQAVHSTECGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFR 936
Q G + CGG L + +S + D YP C W I + ++L
Sbjct: 132 QESGVSPSPQSTCGGLLSGP---RGFFSSPNYPDP-YPPNTHCVWHIQVATDHAIQLKIE 187
Query: 937 TFEVEEEADCGYDYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKK 996
+E A C +D +E + P L R CG P + + L++ F +D ++
Sbjct: 188 ALSIESVASCLFDRLEL--SPEPEGPLL-RVCGRVPPPTLNTNASHLLVVFVSDSSVEGF 244
Query: 997 GFHARY 1002
GFHA Y
Sbjct: 245 GFHAWY 250
>gi|7019483 procollagen C-endopeptidase enhancer 2 [Homo sapiens]
Length = 415
Score = 160 bits (405), Expect = 6e-39
Identities = 84/234 (35%), Positives = 127/234 (54%), Gaps = 12/234 (5%)
Query: 351 CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVE 410
CG L +G + GFP YP S C W+I+V G+ +VLNF +DL LC YD+V+
Sbjct: 33 CGGILTGESGFIGSEGFPGVYPPNSKCTWKITVPEGKVVVLNFRFIDLESDNLCRYDFVD 92
Query: 411 VRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEAT------- 463
V +G+ +GRFCG P LVS+ +++ V+ S +N G GF A + A
Sbjct: 93 VYNGH-ANGQRIGRFCGTFRPGALVSSGNKMMVQMISDANTAGNGFMAMFSAAEPNERGD 151
Query: 464 --CGGDMNKDAGQIQSPNYPD-DYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYD 520
CGG +++ +G ++PN+PD DY CVW I + + L F+ F++ER + C YD
Sbjct: 152 QYCGGLLDRPSGSFKTPNWPDRDYPAGVTCVWHIVAPKNQLIELKFEKFDVERDNYCRYD 211
Query: 521 YLEV-RDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANF 573
Y+ V G ++ IG +CG P + S N L ++F+SD S+ GF ++
Sbjct: 212 YVAVFNGGEVNDARRIGKYCGDSPPAPIVSERNELLIQFLSDLSLTADGFIGHY 265
Score = 155 bits (393), Expect = 1e-37
Identities = 85/269 (31%), Positives = 138/269 (51%), Gaps = 37/269 (13%)
Query: 463 TCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDYL 522
TCGG + ++G I S +P Y P+ +C W+ITV EG V L F+ ++E + C YD++
Sbjct: 32 TCGGILTGESGFIGSEGFPGVYPPNSKCTWKITVPEGKVVVLNFRFIDLESDNLCRYDFV 91
Query: 523 EVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECSW 582
+V +G IG FCG +P + SS N++ ++ +SD + GF A F +
Sbjct: 92 DVYNGHANGQR-IGRFCGTFRPGALVSSGNKMMVQMISDANTAGNGFMAMF-----SAAE 145
Query: 583 PDHGGCEHRCVNTLGSYKCACDPGYELAADKKMCEVACGGFITKLNGTITSPGWP-KEYP 641
P+ G ++ CGG + + +G+ +P WP ++YP
Sbjct: 146 PNERGDQY-----------------------------CGGLLDRPSGSFKTPNWPDRDYP 176
Query: 642 TNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVEV-RSGLSPDAKLHGRFCGSETP 700
CVW +VAP I L+FE F++E ++ C+YD+V V G DA+ G++CG P
Sbjct: 177 AGVTCVWHIVAPKNQLIELKFEKFDVERDNYCRYDYVAVFNGGEVNDARRIGKYCGDSPP 236
Query: 701 EVITSQSNNMRVEFKSDNTVSKRGFRAHF 729
I S+ N + ++F SD +++ GF H+
Sbjct: 237 APIVSERNELLIQFLSDLSLTADGFIGHY 265
Score = 134 bits (337), Expect = 4e-31
Identities = 75/237 (31%), Positives = 119/237 (50%), Gaps = 14/237 (5%)
Query: 776 CAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLE 835
C ++ G + S +P YP +CTW I+ G V L F ++E C YD ++
Sbjct: 33 CGGILTGESGFIGSEGFPGVYPPNSKCTWKITVPEGKVVVLNFRFIDLESDNLCRYDFVD 92
Query: 836 MYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQAVHSTE------- 888
+Y+G + +GRFCG+ +P V+SG+ M ++ SDA+ GF A+ S
Sbjct: 93 VYNG-HANGQRIGRFCGTFRPGALVSSGNKMMVQMISDANTAGNGFMAMFSAAEPNERGD 151
Query: 889 --CGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADC 946
CGG L + + + D +YP+ C W IVA +EL F F+VE + C
Sbjct: 152 QYCGGLLD---RPSGSFKTPNWPDRDYPAGVTCVWHIVAPKNQLIELKFEKFDVERDNYC 208
Query: 947 GYDYMEAYDGYD-SSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARY 1002
YDY+ ++G + + A R+G++CG P I S + L+I+F +D ++ GF Y
Sbjct: 209 RYDYVAVFNGGEVNDARRIGKYCGDSPPAPIVSERNELLIQFLSDLSLTADGFIGHY 265
Score = 65.5 bits (158), Expect = 2e-10
Identities = 29/94 (30%), Positives = 55/94 (58%), Gaps = 1/94 (1%)
Query: 913 YPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGYDYMEAYDGYDSSAPRLGRFCGSGP 972
YP ++C W I +G V L FR ++E + C YD+++ Y+G+ ++ R+GRFCG+
Sbjct: 53 YPPNSKCTWKITVPEGKVVVLNFRFIDLESDNLCRYDFVDVYNGH-ANGQRIGRFCGTFR 111
Query: 973 LEEIYSAGDSLMIRFRTDDTINKKGFHARYTSTK 1006
+ S+G+ +M++ +D GF A +++ +
Sbjct: 112 PGALVSSGNKMMVQMISDANTAGNGFMAMFSAAE 145
>gi|41872572 neuropilin 2 isoform 3 precursor [Homo sapiens]
Length = 909
Score = 155 bits (391), Expect = 2e-37
Identities = 93/276 (33%), Positives = 140/276 (50%), Gaps = 47/276 (17%)
Query: 464 CGGDMN-KDAGQIQSPNYPDDYRPSKECVWRITVSE-GFHVGLTFQA-FEIERHDSCAYD 520
CGG +N KDAG I SP YP DY + C W + E + L F FEIE+HD C YD
Sbjct: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHD-CKYD 86
Query: 521 YLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDEC 580
++E+RDG +E + L+G CG P + SS + L++KF SD + AGF+ + E+ +
Sbjct: 87 FIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRY--EIFKT 144
Query: 581 SWPDHGGCEHRCVNTLGSYKCACDPGYELAADKKMCEVACGGFITKLNGTITSPGWPKEY 640
D C T NGTI SPG+P++Y
Sbjct: 145 GSED-----------------------------------CSKNFTSPNGTIESPGFPEKY 169
Query: 641 PTNKNCVWQVVAPAQYRISLQFEVFELE------GNDVCKYDFVEVRSGLSPDAKLHGRF 694
P N +C + ++A + I LQF +F+LE G CKYD++++ G+ L G++
Sbjct: 170 PHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKY 229
Query: 695 CGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFF 730
CG++TP + S + + + F +D V+K GF A ++
Sbjct: 230 CGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARYY 265
Score = 146 bits (368), Expect = 1e-34
Identities = 80/241 (33%), Positives = 126/241 (52%), Gaps = 16/241 (6%)
Query: 349 PACGETLQDT-TGNFSAPGFPNGYPSYSHCVWRI-SVTPGEKIVLNFTSMDLFKSRLCWY 406
P CG L G ++PG+P YPS+ +C W + + P +KIVLNF + C Y
Sbjct: 26 PPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCKY 85
Query: 407 DYVEVRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYE----- 461
D++E+RDG A LLG+ CG+ P ++S+ S L+++F S G GF YE
Sbjct: 86 DFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTG 145
Query: 462 -ATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHD----- 515
C + G I+SP +P+ Y + +C + I + L F F++E HD
Sbjct: 146 SEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLE-HDPLQVG 204
Query: 516 --SCAYDYLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANF 573
C YD+L++ DG LIG +CG + P +++SS+ L + F +D ++ K GF+A +
Sbjct: 205 EGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264
Query: 574 F 574
+
Sbjct: 265 Y 265
Score = 142 bits (358), Expect = 2e-33
Identities = 87/273 (31%), Positives = 136/273 (49%), Gaps = 47/273 (17%)
Query: 620 CGGFI-TKLNGTITSPGWPKEYPTNKNCVWQVVAPA-QYRISLQFEV-FELEGNDVCKYD 676
CGG + +K G ITSPG+P++YP+++NC W V AP +I L F FE+E +D CKYD
Sbjct: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHD-CKYD 86
Query: 677 FVEVRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDEC 736
F+E+R G S A L G+ CG+ P I S + + ++F SD GF
Sbjct: 87 FIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLR-------- 138
Query: 737 AKDNGGCQHECVNTFGSYLCRCRNGYWLHENGHDCKEAGCAHKISSVEGTLASPNWPDKY 796
Y + + G + C+ +S GT+ SP +P+KY
Sbjct: 139 -------------------------YEIFKTGSE----DCSKNFTSPNGTIESPGFPEKY 169
Query: 797 PSRRECTWNISSTAGHRVKLTFNEFEIEQ------HQECAYDHLEMYDGPDSLAPILGRF 850
P +CT+ I + + L F F++E +C YD L+++DG + P++G++
Sbjct: 170 PHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKY 229
Query: 851 CGSKKPDPTVASGSSMFLRFYSDASVQRKGFQA 883
CG+K P +S + L F++D +V + GF A
Sbjct: 230 CGTKTPSELRSSTGILSLTFHTDMAVAKDGFSA 262
Score = 129 bits (324), Expect = 1e-29
Identities = 76/242 (31%), Positives = 123/242 (50%), Gaps = 20/242 (8%)
Query: 776 CAHKISSVE-GTLASPNWPDKYPSRRECTWNI-SSTAGHRVKLTFN-EFEIEQHQECAYD 832
C +++S + G + SP +P YPS + C W + + ++ L FN FEIE+H +C YD
Sbjct: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKH-DCKYD 86
Query: 833 HLEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQAVH------S 886
+E+ DG A +LG+ CG+ P ++SGS ++++F SD + Q GF + S
Sbjct: 87 FIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTGS 146
Query: 887 TECGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEE---- 942
+C + T E + YP C + I+A+ + L F F++E
Sbjct: 147 EDCSKNFTSPNGTIESPGFPE----KYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQ 202
Query: 943 --EADCGYDYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHA 1000
E DC YD+++ +DG P +G++CG+ E+ S+ L + F TD + K GF A
Sbjct: 203 VGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSA 262
Query: 1001 RY 1002
RY
Sbjct: 263 RY 264
>gi|41872567 neuropilin 2 isoform 5 precursor [Homo sapiens]
Length = 901
Score = 155 bits (391), Expect = 2e-37
Identities = 93/276 (33%), Positives = 140/276 (50%), Gaps = 47/276 (17%)
Query: 464 CGGDMN-KDAGQIQSPNYPDDYRPSKECVWRITVSE-GFHVGLTFQA-FEIERHDSCAYD 520
CGG +N KDAG I SP YP DY + C W + E + L F FEIE+HD C YD
Sbjct: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHD-CKYD 86
Query: 521 YLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDEC 580
++E+RDG +E + L+G CG P + SS + L++KF SD + AGF+ + E+ +
Sbjct: 87 FIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRY--EIFKT 144
Query: 581 SWPDHGGCEHRCVNTLGSYKCACDPGYELAADKKMCEVACGGFITKLNGTITSPGWPKEY 640
D C T NGTI SPG+P++Y
Sbjct: 145 GSED-----------------------------------CSKNFTSPNGTIESPGFPEKY 169
Query: 641 PTNKNCVWQVVAPAQYRISLQFEVFELE------GNDVCKYDFVEVRSGLSPDAKLHGRF 694
P N +C + ++A + I LQF +F+LE G CKYD++++ G+ L G++
Sbjct: 170 PHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKY 229
Query: 695 CGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFF 730
CG++TP + S + + + F +D V+K GF A ++
Sbjct: 230 CGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARYY 265
Score = 146 bits (368), Expect = 1e-34
Identities = 80/241 (33%), Positives = 126/241 (52%), Gaps = 16/241 (6%)
Query: 349 PACGETLQDT-TGNFSAPGFPNGYPSYSHCVWRI-SVTPGEKIVLNFTSMDLFKSRLCWY 406
P CG L G ++PG+P YPS+ +C W + + P +KIVLNF + C Y
Sbjct: 26 PPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCKY 85
Query: 407 DYVEVRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYE----- 461
D++E+RDG A LLG+ CG+ P ++S+ S L+++F S G GF YE
Sbjct: 86 DFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTG 145
Query: 462 -ATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHD----- 515
C + G I+SP +P+ Y + +C + I + L F F++E HD
Sbjct: 146 SEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLE-HDPLQVG 204
Query: 516 --SCAYDYLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANF 573
C YD+L++ DG LIG +CG + P +++SS+ L + F +D ++ K GF+A +
Sbjct: 205 EGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264
Query: 574 F 574
+
Sbjct: 265 Y 265
Score = 142 bits (358), Expect = 2e-33
Identities = 87/273 (31%), Positives = 136/273 (49%), Gaps = 47/273 (17%)
Query: 620 CGGFI-TKLNGTITSPGWPKEYPTNKNCVWQVVAPA-QYRISLQFEV-FELEGNDVCKYD 676
CGG + +K G ITSPG+P++YP+++NC W V AP +I L F FE+E +D CKYD
Sbjct: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHD-CKYD 86
Query: 677 FVEVRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDEC 736
F+E+R G S A L G+ CG+ P I S + + ++F SD GF
Sbjct: 87 FIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLR-------- 138
Query: 737 AKDNGGCQHECVNTFGSYLCRCRNGYWLHENGHDCKEAGCAHKISSVEGTLASPNWPDKY 796
Y + + G + C+ +S GT+ SP +P+KY
Sbjct: 139 -------------------------YEIFKTGSE----DCSKNFTSPNGTIESPGFPEKY 169
Query: 797 PSRRECTWNISSTAGHRVKLTFNEFEIEQ------HQECAYDHLEMYDGPDSLAPILGRF 850
P +CT+ I + + L F F++E +C YD L+++DG + P++G++
Sbjct: 170 PHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKY 229
Query: 851 CGSKKPDPTVASGSSMFLRFYSDASVQRKGFQA 883
CG+K P +S + L F++D +V + GF A
Sbjct: 230 CGTKTPSELRSSTGILSLTFHTDMAVAKDGFSA 262
Score = 129 bits (324), Expect = 1e-29
Identities = 76/242 (31%), Positives = 123/242 (50%), Gaps = 20/242 (8%)
Query: 776 CAHKISSVE-GTLASPNWPDKYPSRRECTWNI-SSTAGHRVKLTFN-EFEIEQHQECAYD 832
C +++S + G + SP +P YPS + C W + + ++ L FN FEIE+H +C YD
Sbjct: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKH-DCKYD 86
Query: 833 HLEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQAVH------S 886
+E+ DG A +LG+ CG+ P ++SGS ++++F SD + Q GF + S
Sbjct: 87 FIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTGS 146
Query: 887 TECGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEE---- 942
+C + T E + YP C + I+A+ + L F F++E
Sbjct: 147 EDCSKNFTSPNGTIESPGFPE----KYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQ 202
Query: 943 --EADCGYDYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHA 1000
E DC YD+++ +DG P +G++CG+ E+ S+ L + F TD + K GF A
Sbjct: 203 VGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSA 262
Query: 1001 RY 1002
RY
Sbjct: 263 RY 264
>gi|41872562 neuropilin 2 isoform 1 precursor [Homo sapiens]
Length = 931
Score = 155 bits (391), Expect = 2e-37
Identities = 93/276 (33%), Positives = 140/276 (50%), Gaps = 47/276 (17%)
Query: 464 CGGDMN-KDAGQIQSPNYPDDYRPSKECVWRITVSE-GFHVGLTFQA-FEIERHDSCAYD 520
CGG +N KDAG I SP YP DY + C W + E + L F FEIE+HD C YD
Sbjct: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHD-CKYD 86
Query: 521 YLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDEC 580
++E+RDG +E + L+G CG P + SS + L++KF SD + AGF+ + E+ +
Sbjct: 87 FIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRY--EIFKT 144
Query: 581 SWPDHGGCEHRCVNTLGSYKCACDPGYELAADKKMCEVACGGFITKLNGTITSPGWPKEY 640
D C T NGTI SPG+P++Y
Sbjct: 145 GSED-----------------------------------CSKNFTSPNGTIESPGFPEKY 169
Query: 641 PTNKNCVWQVVAPAQYRISLQFEVFELE------GNDVCKYDFVEVRSGLSPDAKLHGRF 694
P N +C + ++A + I LQF +F+LE G CKYD++++ G+ L G++
Sbjct: 170 PHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKY 229
Query: 695 CGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFF 730
CG++TP + S + + + F +D V+K GF A ++
Sbjct: 230 CGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARYY 265
Score = 146 bits (368), Expect = 1e-34
Identities = 80/241 (33%), Positives = 126/241 (52%), Gaps = 16/241 (6%)
Query: 349 PACGETLQDT-TGNFSAPGFPNGYPSYSHCVWRI-SVTPGEKIVLNFTSMDLFKSRLCWY 406
P CG L G ++PG+P YPS+ +C W + + P +KIVLNF + C Y
Sbjct: 26 PPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCKY 85
Query: 407 DYVEVRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYE----- 461
D++E+RDG A LLG+ CG+ P ++S+ S L+++F S G GF YE
Sbjct: 86 DFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTG 145
Query: 462 -ATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHD----- 515
C + G I+SP +P+ Y + +C + I + L F F++E HD
Sbjct: 146 SEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLE-HDPLQVG 204
Query: 516 --SCAYDYLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANF 573
C YD+L++ DG LIG +CG + P +++SS+ L + F +D ++ K GF+A +
Sbjct: 205 EGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264
Query: 574 F 574
+
Sbjct: 265 Y 265
Score = 142 bits (358), Expect = 2e-33
Identities = 87/273 (31%), Positives = 136/273 (49%), Gaps = 47/273 (17%)
Query: 620 CGGFI-TKLNGTITSPGWPKEYPTNKNCVWQVVAPA-QYRISLQFEV-FELEGNDVCKYD 676
CGG + +K G ITSPG+P++YP+++NC W V AP +I L F FE+E +D CKYD
Sbjct: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHD-CKYD 86
Query: 677 FVEVRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDEC 736
F+E+R G S A L G+ CG+ P I S + + ++F SD GF
Sbjct: 87 FIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLR-------- 138
Query: 737 AKDNGGCQHECVNTFGSYLCRCRNGYWLHENGHDCKEAGCAHKISSVEGTLASPNWPDKY 796
Y + + G + C+ +S GT+ SP +P+KY
Sbjct: 139 -------------------------YEIFKTGSE----DCSKNFTSPNGTIESPGFPEKY 169
Query: 797 PSRRECTWNISSTAGHRVKLTFNEFEIEQ------HQECAYDHLEMYDGPDSLAPILGRF 850
P +CT+ I + + L F F++E +C YD L+++DG + P++G++
Sbjct: 170 PHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKY 229
Query: 851 CGSKKPDPTVASGSSMFLRFYSDASVQRKGFQA 883
CG+K P +S + L F++D +V + GF A
Sbjct: 230 CGTKTPSELRSSTGILSLTFHTDMAVAKDGFSA 262
Score = 129 bits (324), Expect = 1e-29
Identities = 76/242 (31%), Positives = 123/242 (50%), Gaps = 20/242 (8%)
Query: 776 CAHKISSVE-GTLASPNWPDKYPSRRECTWNI-SSTAGHRVKLTFN-EFEIEQHQECAYD 832
C +++S + G + SP +P YPS + C W + + ++ L FN FEIE+H +C YD
Sbjct: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKH-DCKYD 86
Query: 833 HLEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQAVH------S 886
+E+ DG A +LG+ CG+ P ++SGS ++++F SD + Q GF + S
Sbjct: 87 FIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTGS 146
Query: 887 TECGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEE---- 942
+C + T E + YP C + I+A+ + L F F++E
Sbjct: 147 EDCSKNFTSPNGTIESPGFPE----KYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQ 202
Query: 943 --EADCGYDYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHA 1000
E DC YD+++ +DG P +G++CG+ E+ S+ L + F TD + K GF A
Sbjct: 203 VGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSA 262
Query: 1001 RY 1002
RY
Sbjct: 263 RY 264
>gi|41872557 neuropilin 2 isoform 6 precursor [Homo sapiens]
Length = 555
Score = 155 bits (391), Expect = 2e-37
Identities = 93/276 (33%), Positives = 140/276 (50%), Gaps = 47/276 (17%)
Query: 464 CGGDMN-KDAGQIQSPNYPDDYRPSKECVWRITVSE-GFHVGLTFQA-FEIERHDSCAYD 520
CGG +N KDAG I SP YP DY + C W + E + L F FEIE+HD C YD
Sbjct: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHD-CKYD 86
Query: 521 YLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDEC 580
++E+RDG +E + L+G CG P + SS + L++KF SD + AGF+ + E+ +
Sbjct: 87 FIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRY--EIFKT 144
Query: 581 SWPDHGGCEHRCVNTLGSYKCACDPGYELAADKKMCEVACGGFITKLNGTITSPGWPKEY 640
D C T NGTI SPG+P++Y
Sbjct: 145 GSED-----------------------------------CSKNFTSPNGTIESPGFPEKY 169
Query: 641 PTNKNCVWQVVAPAQYRISLQFEVFELE------GNDVCKYDFVEVRSGLSPDAKLHGRF 694
P N +C + ++A + I LQF +F+LE G CKYD++++ G+ L G++
Sbjct: 170 PHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKY 229
Query: 695 CGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFF 730
CG++TP + S + + + F +D V+K GF A ++
Sbjct: 230 CGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARYY 265
Score = 146 bits (368), Expect = 1e-34
Identities = 80/241 (33%), Positives = 126/241 (52%), Gaps = 16/241 (6%)
Query: 349 PACGETLQDT-TGNFSAPGFPNGYPSYSHCVWRI-SVTPGEKIVLNFTSMDLFKSRLCWY 406
P CG L G ++PG+P YPS+ +C W + + P +KIVLNF + C Y
Sbjct: 26 PPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCKY 85
Query: 407 DYVEVRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYE----- 461
D++E+RDG A LLG+ CG+ P ++S+ S L+++F S G GF YE
Sbjct: 86 DFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTG 145
Query: 462 -ATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHD----- 515
C + G I+SP +P+ Y + +C + I + L F F++E HD
Sbjct: 146 SEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLE-HDPLQVG 204
Query: 516 --SCAYDYLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANF 573
C YD+L++ DG LIG +CG + P +++SS+ L + F +D ++ K GF+A +
Sbjct: 205 EGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264
Query: 574 F 574
+
Sbjct: 265 Y 265
Score = 142 bits (358), Expect = 2e-33
Identities = 87/273 (31%), Positives = 136/273 (49%), Gaps = 47/273 (17%)
Query: 620 CGGFI-TKLNGTITSPGWPKEYPTNKNCVWQVVAPA-QYRISLQFEV-FELEGNDVCKYD 676
CGG + +K G ITSPG+P++YP+++NC W V AP +I L F FE+E +D CKYD
Sbjct: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHD-CKYD 86
Query: 677 FVEVRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDEC 736
F+E+R G S A L G+ CG+ P I S + + ++F SD GF
Sbjct: 87 FIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLR-------- 138
Query: 737 AKDNGGCQHECVNTFGSYLCRCRNGYWLHENGHDCKEAGCAHKISSVEGTLASPNWPDKY 796
Y + + G + C+ +S GT+ SP +P+KY
Sbjct: 139 -------------------------YEIFKTGSE----DCSKNFTSPNGTIESPGFPEKY 169
Query: 797 PSRRECTWNISSTAGHRVKLTFNEFEIEQ------HQECAYDHLEMYDGPDSLAPILGRF 850
P +CT+ I + + L F F++E +C YD L+++DG + P++G++
Sbjct: 170 PHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKY 229
Query: 851 CGSKKPDPTVASGSSMFLRFYSDASVQRKGFQA 883
CG+K P +S + L F++D +V + GF A
Sbjct: 230 CGTKTPSELRSSTGILSLTFHTDMAVAKDGFSA 262
Score = 129 bits (324), Expect = 1e-29
Identities = 76/242 (31%), Positives = 123/242 (50%), Gaps = 20/242 (8%)
Query: 776 CAHKISSVE-GTLASPNWPDKYPSRRECTWNI-SSTAGHRVKLTFN-EFEIEQHQECAYD 832
C +++S + G + SP +P YPS + C W + + ++ L FN FEIE+H +C YD
Sbjct: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKH-DCKYD 86
Query: 833 HLEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQAVH------S 886
+E+ DG A +LG+ CG+ P ++SGS ++++F SD + Q GF + S
Sbjct: 87 FIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTGS 146
Query: 887 TECGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEE---- 942
+C + T E + YP C + I+A+ + L F F++E
Sbjct: 147 EDCSKNFTSPNGTIESPGFPE----KYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQ 202
Query: 943 --EADCGYDYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHA 1000
E DC YD+++ +DG P +G++CG+ E+ S+ L + F TD + K GF A
Sbjct: 203 VGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSA 262
Query: 1001 RY 1002
RY
Sbjct: 263 RY 264
>gi|41872544 neuropilin 2 isoform 4 precursor [Homo sapiens]
Length = 906
Score = 155 bits (391), Expect = 2e-37
Identities = 93/276 (33%), Positives = 140/276 (50%), Gaps = 47/276 (17%)
Query: 464 CGGDMN-KDAGQIQSPNYPDDYRPSKECVWRITVSE-GFHVGLTFQA-FEIERHDSCAYD 520
CGG +N KDAG I SP YP DY + C W + E + L F FEIE+HD C YD
Sbjct: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHD-CKYD 86
Query: 521 YLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDEC 580
++E+RDG +E + L+G CG P + SS + L++KF SD + AGF+ + E+ +
Sbjct: 87 FIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRY--EIFKT 144
Query: 581 SWPDHGGCEHRCVNTLGSYKCACDPGYELAADKKMCEVACGGFITKLNGTITSPGWPKEY 640
D C T NGTI SPG+P++Y
Sbjct: 145 GSED-----------------------------------CSKNFTSPNGTIESPGFPEKY 169
Query: 641 PTNKNCVWQVVAPAQYRISLQFEVFELE------GNDVCKYDFVEVRSGLSPDAKLHGRF 694
P N +C + ++A + I LQF +F+LE G CKYD++++ G+ L G++
Sbjct: 170 PHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKY 229
Query: 695 CGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFF 730
CG++TP + S + + + F +D V+K GF A ++
Sbjct: 230 CGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARYY 265
Score = 146 bits (368), Expect = 1e-34
Identities = 80/241 (33%), Positives = 126/241 (52%), Gaps = 16/241 (6%)
Query: 349 PACGETLQDT-TGNFSAPGFPNGYPSYSHCVWRI-SVTPGEKIVLNFTSMDLFKSRLCWY 406
P CG L G ++PG+P YPS+ +C W + + P +KIVLNF + C Y
Sbjct: 26 PPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCKY 85
Query: 407 DYVEVRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYE----- 461
D++E+RDG A LLG+ CG+ P ++S+ S L+++F S G GF YE
Sbjct: 86 DFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTG 145
Query: 462 -ATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHD----- 515
C + G I+SP +P+ Y + +C + I + L F F++E HD
Sbjct: 146 SEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLE-HDPLQVG 204
Query: 516 --SCAYDYLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANF 573
C YD+L++ DG LIG +CG + P +++SS+ L + F +D ++ K GF+A +
Sbjct: 205 EGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264
Query: 574 F 574
+
Sbjct: 265 Y 265
Score = 142 bits (358), Expect = 2e-33
Identities = 87/273 (31%), Positives = 136/273 (49%), Gaps = 47/273 (17%)
Query: 620 CGGFI-TKLNGTITSPGWPKEYPTNKNCVWQVVAPA-QYRISLQFEV-FELEGNDVCKYD 676
CGG + +K G ITSPG+P++YP+++NC W V AP +I L F FE+E +D CKYD
Sbjct: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHD-CKYD 86
Query: 677 FVEVRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDEC 736
F+E+R G S A L G+ CG+ P I S + + ++F SD GF
Sbjct: 87 FIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLR-------- 138
Query: 737 AKDNGGCQHECVNTFGSYLCRCRNGYWLHENGHDCKEAGCAHKISSVEGTLASPNWPDKY 796
Y + + G + C+ +S GT+ SP +P+KY
Sbjct: 139 -------------------------YEIFKTGSE----DCSKNFTSPNGTIESPGFPEKY 169
Query: 797 PSRRECTWNISSTAGHRVKLTFNEFEIEQ------HQECAYDHLEMYDGPDSLAPILGRF 850
P +CT+ I + + L F F++E +C YD L+++DG + P++G++
Sbjct: 170 PHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKY 229
Query: 851 CGSKKPDPTVASGSSMFLRFYSDASVQRKGFQA 883
CG+K P +S + L F++D +V + GF A
Sbjct: 230 CGTKTPSELRSSTGILSLTFHTDMAVAKDGFSA 262
Score = 129 bits (324), Expect = 1e-29
Identities = 76/242 (31%), Positives = 123/242 (50%), Gaps = 20/242 (8%)
Query: 776 CAHKISSVE-GTLASPNWPDKYPSRRECTWNI-SSTAGHRVKLTFN-EFEIEQHQECAYD 832
C +++S + G + SP +P YPS + C W + + ++ L FN FEIE+H +C YD
Sbjct: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKH-DCKYD 86
Query: 833 HLEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQAVH------S 886
+E+ DG A +LG+ CG+ P ++SGS ++++F SD + Q GF + S
Sbjct: 87 FIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTGS 146
Query: 887 TECGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEE---- 942
+C + T E + YP C + I+A+ + L F F++E
Sbjct: 147 EDCSKNFTSPNGTIESPGFPE----KYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQ 202
Query: 943 --EADCGYDYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHA 1000
E DC YD+++ +DG P +G++CG+ E+ S+ L + F TD + K GF A
Sbjct: 203 VGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSA 262
Query: 1001 RY 1002
RY
Sbjct: 263 RY 264
>gi|41872533 neuropilin 2 isoform 2 precursor [Homo sapiens]
Length = 926
Score = 155 bits (391), Expect = 2e-37
Identities = 93/276 (33%), Positives = 140/276 (50%), Gaps = 47/276 (17%)
Query: 464 CGGDMN-KDAGQIQSPNYPDDYRPSKECVWRITVSE-GFHVGLTFQA-FEIERHDSCAYD 520
CGG +N KDAG I SP YP DY + C W + E + L F FEIE+HD C YD
Sbjct: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHD-CKYD 86
Query: 521 YLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDEC 580
++E+RDG +E + L+G CG P + SS + L++KF SD + AGF+ + E+ +
Sbjct: 87 FIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRY--EIFKT 144
Query: 581 SWPDHGGCEHRCVNTLGSYKCACDPGYELAADKKMCEVACGGFITKLNGTITSPGWPKEY 640
D C T NGTI SPG+P++Y
Sbjct: 145 GSED-----------------------------------CSKNFTSPNGTIESPGFPEKY 169
Query: 641 PTNKNCVWQVVAPAQYRISLQFEVFELE------GNDVCKYDFVEVRSGLSPDAKLHGRF 694
P N +C + ++A + I LQF +F+LE G CKYD++++ G+ L G++
Sbjct: 170 PHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKY 229
Query: 695 CGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFF 730
CG++TP + S + + + F +D V+K GF A ++
Sbjct: 230 CGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARYY 265
Score = 146 bits (368), Expect = 1e-34
Identities = 80/241 (33%), Positives = 126/241 (52%), Gaps = 16/241 (6%)
Query: 349 PACGETLQDT-TGNFSAPGFPNGYPSYSHCVWRI-SVTPGEKIVLNFTSMDLFKSRLCWY 406
P CG L G ++PG+P YPS+ +C W + + P +KIVLNF + C Y
Sbjct: 26 PPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCKY 85
Query: 407 DYVEVRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYE----- 461
D++E+RDG A LLG+ CG+ P ++S+ S L+++F S G GF YE
Sbjct: 86 DFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTG 145
Query: 462 -ATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHD----- 515
C + G I+SP +P+ Y + +C + I + L F F++E HD
Sbjct: 146 SEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLE-HDPLQVG 204
Query: 516 --SCAYDYLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANF 573
C YD+L++ DG LIG +CG + P +++SS+ L + F +D ++ K GF+A +
Sbjct: 205 EGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264
Query: 574 F 574
+
Sbjct: 265 Y 265
Score = 142 bits (358), Expect = 2e-33
Identities = 87/273 (31%), Positives = 136/273 (49%), Gaps = 47/273 (17%)
Query: 620 CGGFI-TKLNGTITSPGWPKEYPTNKNCVWQVVAPA-QYRISLQFEV-FELEGNDVCKYD 676
CGG + +K G ITSPG+P++YP+++NC W V AP +I L F FE+E +D CKYD
Sbjct: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHD-CKYD 86
Query: 677 FVEVRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDEC 736
F+E+R G S A L G+ CG+ P I S + + ++F SD GF
Sbjct: 87 FIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLR-------- 138
Query: 737 AKDNGGCQHECVNTFGSYLCRCRNGYWLHENGHDCKEAGCAHKISSVEGTLASPNWPDKY 796
Y + + G + C+ +S GT+ SP +P+KY
Sbjct: 139 -------------------------YEIFKTGSE----DCSKNFTSPNGTIESPGFPEKY 169
Query: 797 PSRRECTWNISSTAGHRVKLTFNEFEIEQ------HQECAYDHLEMYDGPDSLAPILGRF 850
P +CT+ I + + L F F++E +C YD L+++DG + P++G++
Sbjct: 170 PHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKY 229
Query: 851 CGSKKPDPTVASGSSMFLRFYSDASVQRKGFQA 883
CG+K P +S + L F++D +V + GF A
Sbjct: 230 CGTKTPSELRSSTGILSLTFHTDMAVAKDGFSA 262
Score = 129 bits (324), Expect = 1e-29
Identities = 76/242 (31%), Positives = 123/242 (50%), Gaps = 20/242 (8%)
Query: 776 CAHKISSVE-GTLASPNWPDKYPSRRECTWNI-SSTAGHRVKLTFN-EFEIEQHQECAYD 832
C +++S + G + SP +P YPS + C W + + ++ L FN FEIE+H +C YD
Sbjct: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKH-DCKYD 86
Query: 833 HLEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQAVH------S 886
+E+ DG A +LG+ CG+ P ++SGS ++++F SD + Q GF + S
Sbjct: 87 FIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTGS 146
Query: 887 TECGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEE---- 942
+C + T E + YP C + I+A+ + L F F++E
Sbjct: 147 EDCSKNFTSPNGTIESPGFPE----KYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQ 202
Query: 943 --EADCGYDYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHA 1000
E DC YD+++ +DG P +G++CG+ E+ S+ L + F TD + K GF A
Sbjct: 203 VGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSA 262
Query: 1001 RY 1002
RY
Sbjct: 263 RY 264
>gi|66347875 complement component 1, r subcomponent [Homo sapiens]
Length = 705
Score = 149 bits (376), Expect = 1e-35
Identities = 94/290 (32%), Positives = 144/290 (49%), Gaps = 35/290 (12%)
Query: 626 KLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVEVRSGLS 685
KL G +TSP +PK YP N + P YR+ L F+ F+LE ++ C YD+V++ S
Sbjct: 24 KLFGEVTSPLFPKPYPNNFETTTVITVPTGYRVKLVFQQFDLEPSEGCFYDYVKI----S 79
Query: 686 PDAKLHGRFCGS--------ETPEVITSQSNNMRVEFKSDNTVSK-------RGFRAHFF 730
D K GRFCG + SQ N M + F +D + + +GF A++
Sbjct: 80 ADKKSLGRFCGQLGSPLGNPPGKKEFMSQGNKMLLTFHTDFSNEENGTIMFYKGFLAYYQ 139
Query: 731 S-DKDECAKDNG--------GCQHECVNTFGSYLCRCRNGYWLHENGHDCKEAGCAHKIS 781
+ D DECA + CQH C N G Y C CR GY L E+ H C+ + +
Sbjct: 140 AVDLDECASRSKLGEEDPQPQCQHLCHNYVGGYFCSCRPGYELQEDRHSCQAECSSELYT 199
Query: 782 SVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNE-FEIEQHQE--CAYDHLEMYD 838
G ++S +P YP C ++I G + L F E F+I+ HQ+ C YD L++Y
Sbjct: 200 EASGYISSLEYPRSYPPDLRCNYSIRVERGLTLHLKFLEPFDIDDHQQVHCPYDQLQIYA 259
Query: 839 GPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQAVHSTE 888
+ +G FCG ++P S +++ L F++D S +G++ ++TE
Sbjct: 260 NGKN----IGEFCGKQRPPDLDTSSNAVDLLFFTDESGDSRGWKLRYTTE 305
Score = 127 bits (318), Expect = 7e-29
Identities = 88/349 (25%), Positives = 159/349 (45%), Gaps = 51/349 (14%)
Query: 473 GQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDYLEVRDGPTEES 532
G++ SP +P Y + E ITV G+ V L FQ F++E + C YDY+++ + +
Sbjct: 27 GEVTSPLFPKPYPNNFETTTVITVPTGYRVKLVFQQFDLEPSEGCFYDYVKI----SADK 82
Query: 533 ALIGHFCGY--------EKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFK--------- 575
+G FCG ++ S N++ + F +D S N+ F+K
Sbjct: 83 KSLGRFCGQLGSPLGNPPGKKEFMSQGNKMLLTFHTDFS-NEENGTIMFYKGFLAYYQAV 141
Query: 576 EVDECSWPDHGG-------CEHRCVNTLGSYKCACDPGYELAADKKMCEVACGG-FITKL 627
++DEC+ G C+H C N +G Y C+C PGYEL D+ C+ C T+
Sbjct: 142 DLDECASRSKLGEEDPQPQCQHLCHNYVGGYFCSCRPGYELQEDRHSCQAECSSELYTEA 201
Query: 628 NGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQF-EVFELEGNDV--CKYDFVEVRSGL 684
+G I+S +P+ YP + C + + + L+F E F+++ + C YD +++ +
Sbjct: 202 SGYISSLEYPRSYPPDLRCNYSIRVERGLTLHLKFLEPFDIDDHQQVHCPYDQLQIYA-- 259
Query: 685 SPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECAKDNGGCQ 744
+ K G FCG + P + + SN + + F +D + RG++ + ++ +C + +
Sbjct: 260 --NGKNIGEFCGKQRPPDLDTSSNAVDLLFFTDESGDSRGWKLRYTTEIIKCPQPKTLDE 317
Query: 745 HECVNTF-------GSYLCRCRNGYWLHENGH-------DCKEAGCAHK 779
+ ++ C+ GY L E C++ G H+
Sbjct: 318 FTIIQNLQPQYQFRDYFIATCKQGYQLIEGNQVLHSFTAVCQDDGTWHR 366
Score = 90.1 bits (222), Expect = 9e-18
Identities = 76/300 (25%), Positives = 131/300 (43%), Gaps = 74/300 (24%)
Query: 771 CKEAGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECA 830
C+ G + G + SP +P YP+ E T I+ G+RVKL F +F++E + C
Sbjct: 13 CRAGGSIPIPQKLFGEVTSPLFPKPYPNNFETTTVITVPTGYRVKLVFQQFDLEPSEGCF 72
Query: 831 YDHLEMYDGPDSLAPILGRFC---GSKKPDPT-----VASGSSMFLRFYSDASVQRKG-- 880
YD++++ S LGRFC GS +P ++ G+ M L F++D S + G
Sbjct: 73 YDYVKISADKKS----LGRFCGQLGSPLGNPPGKKEFMSQGNKMLLTFHTDFSNEENGTI 128
Query: 881 ---------FQAVHSTECGGRLKA----------------------------EVQ----- 898
+QAV EC R K E+Q
Sbjct: 129 MFYKGFLAYYQAVDLDECASRSKLGEEDPQPQCQHLCHNYVGGYFCSCRPGYELQEDRHS 188
Query: 899 -----TKELYSHAQ------FGDNNYPSEARCDWVIVAEDGYGVELTF-RTFEVE--EEA 944
+ ELY+ A +YP + RC++ I E G + L F F+++ ++
Sbjct: 189 CQAECSSELYTEASGYISSLEYPRSYPPDLRCNYSIRVERGLTLHLKFLEPFDIDDHQQV 248
Query: 945 DCGYDYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARYTS 1004
C YD ++ Y ++ +G FCG ++ ++ +++ + F TD++ + +G+ RYT+
Sbjct: 249 HCPYDQLQIY----ANGKNIGEFCGKQRPPDLDTSSNAVDLLFFTDESGDSRGWKLRYTT 304
Score = 82.4 bits (202), Expect = 2e-15
Identities = 76/299 (25%), Positives = 120/299 (40%), Gaps = 80/299 (26%)
Query: 356 QDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVEVRDGY 415
Q G ++P FP YP+ I+V G ++ L F DL S C+YDYV++
Sbjct: 23 QKLFGEVTSPLFPKPYPNNFETTTVITVPTGYRVKLVFQQFDLEPSEGCFYDYVKISAD- 81
Query: 416 WRKAPLLGRFCGDKIPEPL---------VSTDSRLWVEFRSSSN-------ILGKGFFAA 459
+K+ LGRFCG ++ PL +S +++ + F + + + KGF A
Sbjct: 82 -KKS--LGRFCG-QLGSPLGNPPGKKEFMSQGNKMLLTFHTDFSNEENGTIMFYKGFLAY 137
Query: 460 YEAT---------------------------------------------------CGGDM 468
Y+A C ++
Sbjct: 138 YQAVDLDECASRSKLGEEDPQPQCQHLCHNYVGGYFCSCRPGYELQEDRHSCQAECSSEL 197
Query: 469 NKDA-GQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTF-QAFEIERHDS--CAYDYLEV 524
+A G I S YP Y P C + I V G + L F + F+I+ H C YD L++
Sbjct: 198 YTEASGYISSLEYPRSYPPDLRCNYSIRVERGLTLHLKFLEPFDIDDHQQVHCPYDQLQI 257
Query: 525 RDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECSWP 583
IG FCG ++P D+ +SSN + + F +D S + G+ + E+ +C P
Sbjct: 258 ----YANGKNIGEFCGKQRPPDLDTSSNAVDLLFFTDESGDSRGWKLRYTTEIIKCPQP 312
Score = 50.8 bits (120), Expect = 6e-06
Identities = 35/118 (29%), Positives = 52/118 (44%), Gaps = 19/118 (16%)
Query: 913 YPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGYDYMEAYDGYDSSAPRLGRFCG--S 970
YP+ VI GY V+L F+ F++E C YDY++ + LGRFCG
Sbjct: 38 YPNNFETTTVITVPTGYRVKLVFQQFDLEPSEGCFYDYVK----ISADKKSLGRFCGQLG 93
Query: 971 GPL------EEIYSAGDSLMIRFRTDDTINK-------KGFHARYTSTKFQDALHMKK 1015
PL +E S G+ +++ F TD + + KGF A Y + + K
Sbjct: 94 SPLGNPPGKKEFMSQGNKMLLTFHTDFSNEENGTIMFYKGFLAYYQAVDLDECASRSK 151
>gi|239755390 PREDICTED: similar to DMBT1 isoform 1 [Homo sapiens]
Length = 1662
Score = 144 bits (364), Expect = 3e-34
Identities = 115/391 (29%), Positives = 171/391 (43%), Gaps = 50/391 (12%)
Query: 351 CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVE 410
CG L +G FS+P +P YP+ + CVW I V G +I L F+++ L C +DYVE
Sbjct: 1015 CGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVE 1074
Query: 411 VRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEATCGGDMNK 470
+ DG + LLG+ C D + S+ +R+ + FRS + GF A Y +
Sbjct: 1075 IFDGSLNSSLLLGKICNDT-RQIFTSSYNRMTIHFRSDISFQNTGFLAWYNS-----FPS 1128
Query: 471 DAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGL------TFQAFEIE-RHDSCAYDYLE 523
DA ++ N Y C R+ + G G T Q E+ R C
Sbjct: 1129 DA-TLRLVNLNSSYGL---CAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCG----- 1179
Query: 524 VRDGPTEESALIGHFCGYEKPEDVKSSSNR--LWMKFVSDGSINKAGFAANFFKEVDECS 581
R +A G G +DV+ S LW N+ F+ N
Sbjct: 1180 -RAVSALGNAYFGSGSGPITLDDVECSGTESTLWQ------CRNRGWFSHN--------- 1223
Query: 582 WPDHGGCEHR-CVNTLGSYKCACDPGYELAADKKMCEVACGGFITKLNGTITSPGWPKEY 640
C HR + S P L + + +CGGF+++ +G +SP +P Y
Sbjct: 1224 ------CNHREDAGVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPGNY 1277
Query: 641 PTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVEVRSGLSPDAKLHGRFCGSETP 700
P N CVW + YR+++ F +LEG C YD++EV G + L R C
Sbjct: 1278 PNNAKCVWDIEVQNNYRVTVIFRDVQLEGG--CNYDYIEVFDGPYRSSPLIARVCDGARG 1335
Query: 701 EVITSQSNNMRVEFKSDNTVSKRGFRAHFFS 731
TS SN M + F SD+++++RGFRA ++S
Sbjct: 1336 S-FTSSSNFMSIRFISDHSITRRGFRAEYYS 1365
Score = 94.0 bits (232), Expect = 6e-19
Identities = 51/172 (29%), Positives = 86/172 (50%), Gaps = 9/172 (5%)
Query: 620 CGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVE 679
CGGF+ +GT +SP +P YP N CVW++ + YRI+L F +LE + C +D+VE
Sbjct: 1015 CGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVE 1074
Query: 680 VRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECA-- 737
+ G + L G+ C ++T ++ TS N M + F+SD + GF A + S +
Sbjct: 1075 IFDGSLNSSLLLGKIC-NDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDATLR 1133
Query: 738 -----KDNGGCQHEC-VNTFGSYLCRCRNGYWLHENGHDCKEAGCAHKISSV 783
G C + G++ C + + + E C++ GC +S++
Sbjct: 1134 LVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSAL 1185
Score = 87.0 bits (214), Expect = 8e-17
Identities = 51/182 (28%), Positives = 87/182 (47%), Gaps = 9/182 (4%)
Query: 462 ATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDY 521
+ CGG + +G SP+YP Y + +CVW I V+ G+ + L F ++E H +C++DY
Sbjct: 1013 SNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDY 1072
Query: 522 LEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECS 581
+E+ DG S L+G C + + SS NR+ + F SD S GF A + + +
Sbjct: 1073 VEIFDGSLNSSLLLGKICN-DTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDAT 1131
Query: 582 W------PDHGGCEHRC-VNTLGSYKCACDPGYELAADKKMC-EVACGGFITKLNGTITS 633
+G C R + G++ CD + + + +C ++ CG ++ L
Sbjct: 1132 LRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFG 1191
Query: 634 PG 635
G
Sbjct: 1192 SG 1193
Score = 81.3 bits (199), Expect = 4e-15
Identities = 49/163 (30%), Positives = 78/163 (47%), Gaps = 29/163 (17%)
Query: 746 ECVNTFGSYLCRCRNGYWLHENGHDCKEAG-------------------------CAHKI 780
EC T S L +CRN W N + ++AG C +
Sbjct: 1203 ECSGT-ESTLWQCRNRGWFSHNCNHREDAGVICSGNHLSTPAPFLNITRPNTDYSCGGFL 1261
Query: 781 SSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMYDGP 840
S G +SP +P YP+ +C W+I +RV + F + ++E C YD++E++DGP
Sbjct: 1262 SQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLE--GGCNYDYIEVFDGP 1319
Query: 841 DSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQA 883
+P++ R C + T +S + M +RF SD S+ R+GF+A
Sbjct: 1320 YRSSPLIARVCDGARGSFT-SSSNFMSIRFISDHSITRRGFRA 1361
Score = 80.1 bits (196), Expect = 1e-14
Identities = 36/114 (31%), Positives = 66/114 (57%), Gaps = 1/114 (0%)
Query: 774 AGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDH 833
+ C + GT +SP++P YP+ +C W I +G+R+ L F+ ++E H C++D+
Sbjct: 1013 SNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDY 1072
Query: 834 LEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQAVHST 887
+E++DG + + +LG+ C + T +S + M + F SD S Q GF A +++
Sbjct: 1073 VEIFDGSLNSSLLLGKICNDTRQIFT-SSYNRMTIHFRSDISFQNTGFLAWYNS 1125
Score = 75.1 bits (183), Expect = 3e-13
Identities = 44/125 (35%), Positives = 68/125 (54%), Gaps = 7/125 (5%)
Query: 889 CGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGY 948
CGG L Q +S + F NYP+ A+C W I ++ Y V + FR +V+ E C Y
Sbjct: 1257 CGGFLS---QPSGDFS-SPFYPGNYPNNAKCVWDIEVQNNYRVTVIFR--DVQLEGGCNY 1310
Query: 949 DYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARYTSTKFQ 1008
DY+E +DG S+P + R C G S+ + + IRF +D +I ++GF A Y S+
Sbjct: 1311 DYIEVFDGPYRSSPLIARVC-DGARGSFTSSSNFMSIRFISDHSITRRGFRAEYYSSPSN 1369
Query: 1009 DALHM 1013
D+ ++
Sbjct: 1370 DSTNL 1374
Score = 74.3 bits (181), Expect = 5e-13
Identities = 40/118 (33%), Positives = 63/118 (53%), Gaps = 3/118 (2%)
Query: 350 ACGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYV 409
+CG L +G+FS+P +P YP+ + CVW I V ++ + F + L C YDY+
Sbjct: 1256 SCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGG--CNYDYI 1313
Query: 410 EVRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEATCGGD 467
EV DG +R +PL+ R C D S+ + + + F S +I +GF A Y ++ D
Sbjct: 1314 EVFDGPYRSSPLIARVC-DGARGSFTSSSNFMSIRFISDHSITRRGFRAEYYSSPSND 1370
Score = 65.1 bits (157), Expect = 3e-10
Identities = 39/120 (32%), Positives = 61/120 (50%), Gaps = 7/120 (5%)
Query: 886 STECGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEAD 945
S+ CGG L T S+ + YP+ A+C W I GY + L F ++E +
Sbjct: 1012 SSNCGGFLFYASGTFSSPSYPAY----YPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHN 1067
Query: 946 CGYDYMEAYDGYDSSAPRLGRFCGSGPLEEIY-SAGDSLMIRFRTDDTINKKGFHARYTS 1004
C +DY+E +DG +S+ LG+ C +I+ S+ + + I FR+D + GF A Y S
Sbjct: 1068 CSFDYVEIFDGSLNSSLLLGKICND--TRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNS 1125
>gi|239755388 PREDICTED: similar to DMBT1 isoform 2 [Homo sapiens]
Length = 1788
Score = 144 bits (364), Expect = 3e-34
Identities = 115/391 (29%), Positives = 171/391 (43%), Gaps = 50/391 (12%)
Query: 351 CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVE 410
CG L +G FS+P +P YP+ + CVW I V G +I L F+++ L C +DYVE
Sbjct: 1141 CGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVE 1200
Query: 411 VRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEATCGGDMNK 470
+ DG + LLG+ C D + S+ +R+ + FRS + GF A Y +
Sbjct: 1201 IFDGSLNSSLLLGKICNDT-RQIFTSSYNRMTIHFRSDISFQNTGFLAWYNS-----FPS 1254
Query: 471 DAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGL------TFQAFEIE-RHDSCAYDYLE 523
DA ++ N Y C R+ + G G T Q E+ R C
Sbjct: 1255 DA-TLRLVNLNSSYGL---CAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCG----- 1305
Query: 524 VRDGPTEESALIGHFCGYEKPEDVKSSSNR--LWMKFVSDGSINKAGFAANFFKEVDECS 581
R +A G G +DV+ S LW N+ F+ N
Sbjct: 1306 -RAVSALGNAYFGSGSGPITLDDVECSGTESTLWQ------CRNRGWFSHN--------- 1349
Query: 582 WPDHGGCEHR-CVNTLGSYKCACDPGYELAADKKMCEVACGGFITKLNGTITSPGWPKEY 640
C HR + S P L + + +CGGF+++ +G +SP +P Y
Sbjct: 1350 ------CNHREDAGVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPGNY 1403
Query: 641 PTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVEVRSGLSPDAKLHGRFCGSETP 700
P N CVW + YR+++ F +LEG C YD++EV G + L R C
Sbjct: 1404 PNNAKCVWDIEVQNNYRVTVIFRDVQLEGG--CNYDYIEVFDGPYRSSPLIARVCDGARG 1461
Query: 701 EVITSQSNNMRVEFKSDNTVSKRGFRAHFFS 731
TS SN M + F SD+++++RGFRA ++S
Sbjct: 1462 S-FTSSSNFMSIRFISDHSITRRGFRAEYYS 1491
Score = 94.0 bits (232), Expect = 6e-19
Identities = 51/172 (29%), Positives = 86/172 (50%), Gaps = 9/172 (5%)
Query: 620 CGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVE 679
CGGF+ +GT +SP +P YP N CVW++ + YRI+L F +LE + C +D+VE
Sbjct: 1141 CGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVE 1200
Query: 680 VRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECA-- 737
+ G + L G+ C ++T ++ TS N M + F+SD + GF A + S +
Sbjct: 1201 IFDGSLNSSLLLGKIC-NDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDATLR 1259
Query: 738 -----KDNGGCQHEC-VNTFGSYLCRCRNGYWLHENGHDCKEAGCAHKISSV 783
G C + G++ C + + + E C++ GC +S++
Sbjct: 1260 LVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSAL 1311
Score = 87.0 bits (214), Expect = 8e-17
Identities = 51/182 (28%), Positives = 87/182 (47%), Gaps = 9/182 (4%)
Query: 462 ATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDY 521
+ CGG + +G SP+YP Y + +CVW I V+ G+ + L F ++E H +C++DY
Sbjct: 1139 SNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDY 1198
Query: 522 LEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECS 581
+E+ DG S L+G C + + SS NR+ + F SD S GF A + + +
Sbjct: 1199 VEIFDGSLNSSLLLGKICN-DTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDAT 1257
Query: 582 W------PDHGGCEHRC-VNTLGSYKCACDPGYELAADKKMC-EVACGGFITKLNGTITS 633
+G C R + G++ CD + + + +C ++ CG ++ L
Sbjct: 1258 LRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFG 1317
Query: 634 PG 635
G
Sbjct: 1318 SG 1319
Score = 81.3 bits (199), Expect = 4e-15
Identities = 49/163 (30%), Positives = 78/163 (47%), Gaps = 29/163 (17%)
Query: 746 ECVNTFGSYLCRCRNGYWLHENGHDCKEAG-------------------------CAHKI 780
EC T S L +CRN W N + ++AG C +
Sbjct: 1329 ECSGT-ESTLWQCRNRGWFSHNCNHREDAGVICSGNHLSTPAPFLNITRPNTDYSCGGFL 1387
Query: 781 SSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMYDGP 840
S G +SP +P YP+ +C W+I +RV + F + ++E C YD++E++DGP
Sbjct: 1388 SQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLE--GGCNYDYIEVFDGP 1445
Query: 841 DSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQA 883
+P++ R C + T +S + M +RF SD S+ R+GF+A
Sbjct: 1446 YRSSPLIARVCDGARGSFT-SSSNFMSIRFISDHSITRRGFRA 1487
Score = 80.1 bits (196), Expect = 1e-14
Identities = 36/114 (31%), Positives = 66/114 (57%), Gaps = 1/114 (0%)
Query: 774 AGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDH 833
+ C + GT +SP++P YP+ +C W I +G+R+ L F+ ++E H C++D+
Sbjct: 1139 SNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDY 1198
Query: 834 LEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQAVHST 887
+E++DG + + +LG+ C + T +S + M + F SD S Q GF A +++
Sbjct: 1199 VEIFDGSLNSSLLLGKICNDTRQIFT-SSYNRMTIHFRSDISFQNTGFLAWYNS 1251
Score = 75.1 bits (183), Expect = 3e-13
Identities = 44/125 (35%), Positives = 68/125 (54%), Gaps = 7/125 (5%)
Query: 889 CGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGY 948
CGG L Q +S + F NYP+ A+C W I ++ Y V + FR +V+ E C Y
Sbjct: 1383 CGGFLS---QPSGDFS-SPFYPGNYPNNAKCVWDIEVQNNYRVTVIFR--DVQLEGGCNY 1436
Query: 949 DYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARYTSTKFQ 1008
DY+E +DG S+P + R C G S+ + + IRF +D +I ++GF A Y S+
Sbjct: 1437 DYIEVFDGPYRSSPLIARVC-DGARGSFTSSSNFMSIRFISDHSITRRGFRAEYYSSPSN 1495
Query: 1009 DALHM 1013
D+ ++
Sbjct: 1496 DSTNL 1500
Score = 74.3 bits (181), Expect = 5e-13
Identities = 40/118 (33%), Positives = 63/118 (53%), Gaps = 3/118 (2%)
Query: 350 ACGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYV 409
+CG L +G+FS+P +P YP+ + CVW I V ++ + F + L C YDY+
Sbjct: 1382 SCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGG--CNYDYI 1439
Query: 410 EVRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEATCGGD 467
EV DG +R +PL+ R C D S+ + + + F S +I +GF A Y ++ D
Sbjct: 1440 EVFDGPYRSSPLIARVC-DGARGSFTSSSNFMSIRFISDHSITRRGFRAEYYSSPSND 1496
Score = 65.1 bits (157), Expect = 3e-10
Identities = 39/120 (32%), Positives = 61/120 (50%), Gaps = 7/120 (5%)
Query: 886 STECGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEAD 945
S+ CGG L T S+ + YP+ A+C W I GY + L F ++E +
Sbjct: 1138 SSNCGGFLFYASGTFSSPSYPAY----YPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHN 1193
Query: 946 CGYDYMEAYDGYDSSAPRLGRFCGSGPLEEIY-SAGDSLMIRFRTDDTINKKGFHARYTS 1004
C +DY+E +DG +S+ LG+ C +I+ S+ + + I FR+D + GF A Y S
Sbjct: 1194 CSFDYVEIFDGSLNSSLLLGKICND--TRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNS 1251
>gi|148539844 deleted in malignant brain tumors 1 isoform c precursor
[Homo sapiens]
Length = 2403
Score = 144 bits (364), Expect = 3e-34
Identities = 115/391 (29%), Positives = 171/391 (43%), Gaps = 50/391 (12%)
Query: 351 CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVE 410
CG L +G FS+P +P YP+ + CVW I V G +I L F+++ L C +DYVE
Sbjct: 1756 CGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVE 1815
Query: 411 VRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEATCGGDMNK 470
+ DG + LLG+ C D + S+ +R+ + FRS + GF A Y +
Sbjct: 1816 IFDGSLNSSLLLGKICNDT-RQIFTSSYNRMTIHFRSDISFQNTGFLAWYNS-----FPS 1869
Query: 471 DAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGL------TFQAFEIE-RHDSCAYDYLE 523
DA ++ N Y C R+ + G G T Q E+ R C
Sbjct: 1870 DA-TLRLVNLNSSYGL---CAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCG----- 1920
Query: 524 VRDGPTEESALIGHFCGYEKPEDVKSSSNR--LWMKFVSDGSINKAGFAANFFKEVDECS 581
R +A G G +DV+ S LW N+ F+ N
Sbjct: 1921 -RAVSALGNAYFGSGSGPITLDDVECSGTESTLWQ------CRNRGWFSHN--------- 1964
Query: 582 WPDHGGCEHR-CVNTLGSYKCACDPGYELAADKKMCEVACGGFITKLNGTITSPGWPKEY 640
C HR + S P L + + +CGGF+++ +G +SP +P Y
Sbjct: 1965 ------CNHREDAGVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPGNY 2018
Query: 641 PTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVEVRSGLSPDAKLHGRFCGSETP 700
P N CVW + YR+++ F +LEG C YD++EV G + L R C
Sbjct: 2019 PNNAKCVWDIEVQNNYRVTVIFRDVQLEGG--CNYDYIEVFDGPYRSSPLIARVCDGARG 2076
Query: 701 EVITSQSNNMRVEFKSDNTVSKRGFRAHFFS 731
TS SN M + F SD+++++RGFRA ++S
Sbjct: 2077 S-FTSSSNFMSIRFISDHSITRRGFRAEYYS 2106
Score = 94.0 bits (232), Expect = 6e-19
Identities = 51/172 (29%), Positives = 86/172 (50%), Gaps = 9/172 (5%)
Query: 620 CGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVE 679
CGGF+ +GT +SP +P YP N CVW++ + YRI+L F +LE + C +D+VE
Sbjct: 1756 CGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVE 1815
Query: 680 VRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECA-- 737
+ G + L G+ C ++T ++ TS N M + F+SD + GF A + S +
Sbjct: 1816 IFDGSLNSSLLLGKIC-NDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDATLR 1874
Query: 738 -----KDNGGCQHEC-VNTFGSYLCRCRNGYWLHENGHDCKEAGCAHKISSV 783
G C + G++ C + + + E C++ GC +S++
Sbjct: 1875 LVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSAL 1926
Score = 87.0 bits (214), Expect = 8e-17
Identities = 51/182 (28%), Positives = 87/182 (47%), Gaps = 9/182 (4%)
Query: 462 ATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDY 521
+ CGG + +G SP+YP Y + +CVW I V+ G+ + L F ++E H +C++DY
Sbjct: 1754 SNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDY 1813
Query: 522 LEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECS 581
+E+ DG S L+G C + + SS NR+ + F SD S GF A + + +
Sbjct: 1814 VEIFDGSLNSSLLLGKICN-DTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDAT 1872
Query: 582 W------PDHGGCEHRC-VNTLGSYKCACDPGYELAADKKMC-EVACGGFITKLNGTITS 633
+G C R + G++ CD + + + +C ++ CG ++ L
Sbjct: 1873 LRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFG 1932
Query: 634 PG 635
G
Sbjct: 1933 SG 1934
Score = 81.3 bits (199), Expect = 4e-15
Identities = 49/163 (30%), Positives = 78/163 (47%), Gaps = 29/163 (17%)
Query: 746 ECVNTFGSYLCRCRNGYWLHENGHDCKEAG-------------------------CAHKI 780
EC T S L +CRN W N + ++AG C +
Sbjct: 1944 ECSGT-ESTLWQCRNRGWFSHNCNHREDAGVICSGNHLSTPAPFLNITRPNTDYSCGGFL 2002
Query: 781 SSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMYDGP 840
S G +SP +P YP+ +C W+I +RV + F + ++E C YD++E++DGP
Sbjct: 2003 SQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLE--GGCNYDYIEVFDGP 2060
Query: 841 DSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQA 883
+P++ R C + T +S + M +RF SD S+ R+GF+A
Sbjct: 2061 YRSSPLIARVCDGARGSFT-SSSNFMSIRFISDHSITRRGFRA 2102
Score = 80.1 bits (196), Expect = 1e-14
Identities = 36/114 (31%), Positives = 66/114 (57%), Gaps = 1/114 (0%)
Query: 774 AGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDH 833
+ C + GT +SP++P YP+ +C W I +G+R+ L F+ ++E H C++D+
Sbjct: 1754 SNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDY 1813
Query: 834 LEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQAVHST 887
+E++DG + + +LG+ C + T +S + M + F SD S Q GF A +++
Sbjct: 1814 VEIFDGSLNSSLLLGKICNDTRQIFT-SSYNRMTIHFRSDISFQNTGFLAWYNS 1866
Score = 75.1 bits (183), Expect = 3e-13
Identities = 44/125 (35%), Positives = 68/125 (54%), Gaps = 7/125 (5%)
Query: 889 CGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGY 948
CGG L Q +S + F NYP+ A+C W I ++ Y V + FR +V+ E C Y
Sbjct: 1998 CGGFLS---QPSGDFS-SPFYPGNYPNNAKCVWDIEVQNNYRVTVIFR--DVQLEGGCNY 2051
Query: 949 DYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARYTSTKFQ 1008
DY+E +DG S+P + R C G S+ + + IRF +D +I ++GF A Y S+
Sbjct: 2052 DYIEVFDGPYRSSPLIARVC-DGARGSFTSSSNFMSIRFISDHSITRRGFRAEYYSSPSN 2110
Query: 1009 DALHM 1013
D+ ++
Sbjct: 2111 DSTNL 2115
Score = 74.3 bits (181), Expect = 5e-13
Identities = 40/118 (33%), Positives = 63/118 (53%), Gaps = 3/118 (2%)
Query: 350 ACGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYV 409
+CG L +G+FS+P +P YP+ + CVW I V ++ + F + L C YDY+
Sbjct: 1997 SCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGG--CNYDYI 2054
Query: 410 EVRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEATCGGD 467
EV DG +R +PL+ R C D S+ + + + F S +I +GF A Y ++ D
Sbjct: 2055 EVFDGPYRSSPLIARVC-DGARGSFTSSSNFMSIRFISDHSITRRGFRAEYYSSPSND 2111
Score = 65.1 bits (157), Expect = 3e-10
Identities = 39/120 (32%), Positives = 61/120 (50%), Gaps = 7/120 (5%)
Query: 886 STECGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEAD 945
S+ CGG L T S+ + YP+ A+C W I GY + L F ++E +
Sbjct: 1753 SSNCGGFLFYASGTFSSPSYPAY----YPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHN 1808
Query: 946 CGYDYMEAYDGYDSSAPRLGRFCGSGPLEEIY-SAGDSLMIRFRTDDTINKKGFHARYTS 1004
C +DY+E +DG +S+ LG+ C +I+ S+ + + I FR+D + GF A Y S
Sbjct: 1809 CSFDYVEIFDGSLNSSLLLGKICND--TRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNS 1866
>gi|148539842 deleted in malignant brain tumors 1 isoform b precursor
[Homo sapiens]
Length = 2413
Score = 144 bits (364), Expect = 3e-34
Identities = 115/391 (29%), Positives = 171/391 (43%), Gaps = 50/391 (12%)
Query: 351 CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVE 410
CG L +G FS+P +P YP+ + CVW I V G +I L F+++ L C +DYVE
Sbjct: 1766 CGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVE 1825
Query: 411 VRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEATCGGDMNK 470
+ DG + LLG+ C D + S+ +R+ + FRS + GF A Y +
Sbjct: 1826 IFDGSLNSSLLLGKICNDT-RQIFTSSYNRMTIHFRSDISFQNTGFLAWYNS-----FPS 1879
Query: 471 DAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGL------TFQAFEIE-RHDSCAYDYLE 523
DA ++ N Y C R+ + G G T Q E+ R C
Sbjct: 1880 DA-TLRLVNLNSSYGL---CAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCG----- 1930
Query: 524 VRDGPTEESALIGHFCGYEKPEDVKSSSNR--LWMKFVSDGSINKAGFAANFFKEVDECS 581
R +A G G +DV+ S LW N+ F+ N
Sbjct: 1931 -RAVSALGNAYFGSGSGPITLDDVECSGTESTLWQ------CRNRGWFSHN--------- 1974
Query: 582 WPDHGGCEHR-CVNTLGSYKCACDPGYELAADKKMCEVACGGFITKLNGTITSPGWPKEY 640
C HR + S P L + + +CGGF+++ +G +SP +P Y
Sbjct: 1975 ------CNHREDAGVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPGNY 2028
Query: 641 PTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVEVRSGLSPDAKLHGRFCGSETP 700
P N CVW + YR+++ F +LEG C YD++EV G + L R C
Sbjct: 2029 PNNAKCVWDIEVQNNYRVTVIFRDVQLEGG--CNYDYIEVFDGPYRSSPLIARVCDGARG 2086
Query: 701 EVITSQSNNMRVEFKSDNTVSKRGFRAHFFS 731
TS SN M + F SD+++++RGFRA ++S
Sbjct: 2087 S-FTSSSNFMSIRFISDHSITRRGFRAEYYS 2116
Score = 94.0 bits (232), Expect = 6e-19
Identities = 51/172 (29%), Positives = 86/172 (50%), Gaps = 9/172 (5%)
Query: 620 CGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVE 679
CGGF+ +GT +SP +P YP N CVW++ + YRI+L F +LE + C +D+VE
Sbjct: 1766 CGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVE 1825
Query: 680 VRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECA-- 737
+ G + L G+ C ++T ++ TS N M + F+SD + GF A + S +
Sbjct: 1826 IFDGSLNSSLLLGKIC-NDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDATLR 1884
Query: 738 -----KDNGGCQHEC-VNTFGSYLCRCRNGYWLHENGHDCKEAGCAHKISSV 783
G C + G++ C + + + E C++ GC +S++
Sbjct: 1885 LVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSAL 1936
Score = 87.0 bits (214), Expect = 8e-17
Identities = 51/182 (28%), Positives = 87/182 (47%), Gaps = 9/182 (4%)
Query: 462 ATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDY 521
+ CGG + +G SP+YP Y + +CVW I V+ G+ + L F ++E H +C++DY
Sbjct: 1764 SNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDY 1823
Query: 522 LEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECS 581
+E+ DG S L+G C + + SS NR+ + F SD S GF A + + +
Sbjct: 1824 VEIFDGSLNSSLLLGKICN-DTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDAT 1882
Query: 582 W------PDHGGCEHRC-VNTLGSYKCACDPGYELAADKKMC-EVACGGFITKLNGTITS 633
+G C R + G++ CD + + + +C ++ CG ++ L
Sbjct: 1883 LRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFG 1942
Query: 634 PG 635
G
Sbjct: 1943 SG 1944
Score = 81.3 bits (199), Expect = 4e-15
Identities = 49/163 (30%), Positives = 78/163 (47%), Gaps = 29/163 (17%)
Query: 746 ECVNTFGSYLCRCRNGYWLHENGHDCKEAG-------------------------CAHKI 780
EC T S L +CRN W N + ++AG C +
Sbjct: 1954 ECSGT-ESTLWQCRNRGWFSHNCNHREDAGVICSGNHLSTPAPFLNITRPNTDYSCGGFL 2012
Query: 781 SSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMYDGP 840
S G +SP +P YP+ +C W+I +RV + F + ++E C YD++E++DGP
Sbjct: 2013 SQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLE--GGCNYDYIEVFDGP 2070
Query: 841 DSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQA 883
+P++ R C + T +S + M +RF SD S+ R+GF+A
Sbjct: 2071 YRSSPLIARVCDGARGSFT-SSSNFMSIRFISDHSITRRGFRA 2112
Score = 80.1 bits (196), Expect = 1e-14
Identities = 36/114 (31%), Positives = 66/114 (57%), Gaps = 1/114 (0%)
Query: 774 AGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDH 833
+ C + GT +SP++P YP+ +C W I +G+R+ L F+ ++E H C++D+
Sbjct: 1764 SNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDY 1823
Query: 834 LEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQAVHST 887
+E++DG + + +LG+ C + T +S + M + F SD S Q GF A +++
Sbjct: 1824 VEIFDGSLNSSLLLGKICNDTRQIFT-SSYNRMTIHFRSDISFQNTGFLAWYNS 1876
Score = 75.1 bits (183), Expect = 3e-13
Identities = 44/125 (35%), Positives = 68/125 (54%), Gaps = 7/125 (5%)
Query: 889 CGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGY 948
CGG L Q +S + F NYP+ A+C W I ++ Y V + FR +V+ E C Y
Sbjct: 2008 CGGFLS---QPSGDFS-SPFYPGNYPNNAKCVWDIEVQNNYRVTVIFR--DVQLEGGCNY 2061
Query: 949 DYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARYTSTKFQ 1008
DY+E +DG S+P + R C G S+ + + IRF +D +I ++GF A Y S+
Sbjct: 2062 DYIEVFDGPYRSSPLIARVC-DGARGSFTSSSNFMSIRFISDHSITRRGFRAEYYSSPSN 2120
Query: 1009 DALHM 1013
D+ ++
Sbjct: 2121 DSTNL 2125
Score = 74.3 bits (181), Expect = 5e-13
Identities = 40/118 (33%), Positives = 63/118 (53%), Gaps = 3/118 (2%)
Query: 350 ACGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYV 409
+CG L +G+FS+P +P YP+ + CVW I V ++ + F + L C YDY+
Sbjct: 2007 SCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGG--CNYDYI 2064
Query: 410 EVRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEATCGGD 467
EV DG +R +PL+ R C D S+ + + + F S +I +GF A Y ++ D
Sbjct: 2065 EVFDGPYRSSPLIARVC-DGARGSFTSSSNFMSIRFISDHSITRRGFRAEYYSSPSND 2121
Score = 65.1 bits (157), Expect = 3e-10
Identities = 39/120 (32%), Positives = 61/120 (50%), Gaps = 7/120 (5%)
Query: 886 STECGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEAD 945
S+ CGG L T S+ + YP+ A+C W I GY + L F ++E +
Sbjct: 1763 SSNCGGFLFYASGTFSSPSYPAY----YPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHN 1818
Query: 946 CGYDYMEAYDGYDSSAPRLGRFCGSGPLEEIY-SAGDSLMIRFRTDDTINKKGFHARYTS 1004
C +DY+E +DG +S+ LG+ C +I+ S+ + + I FR+D + GF A Y S
Sbjct: 1819 CSFDYVEIFDGSLNSSLLLGKICND--TRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNS 1876
>gi|148539840 deleted in malignant brain tumors 1 isoform a precursor
[Homo sapiens]
Length = 1785
Score = 144 bits (364), Expect = 3e-34
Identities = 115/391 (29%), Positives = 171/391 (43%), Gaps = 50/391 (12%)
Query: 351 CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVE 410
CG L +G FS+P +P YP+ + CVW I V G +I L F+++ L C +DYVE
Sbjct: 1138 CGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVE 1197
Query: 411 VRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEATCGGDMNK 470
+ DG + LLG+ C D + S+ +R+ + FRS + GF A Y +
Sbjct: 1198 IFDGSLNSSLLLGKICNDT-RQIFTSSYNRMTIHFRSDISFQNTGFLAWYNS-----FPS 1251
Query: 471 DAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGL------TFQAFEIE-RHDSCAYDYLE 523
DA ++ N Y C R+ + G G T Q E+ R C
Sbjct: 1252 DA-TLRLVNLNSSYGL---CAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCG----- 1302
Query: 524 VRDGPTEESALIGHFCGYEKPEDVKSSSNR--LWMKFVSDGSINKAGFAANFFKEVDECS 581
R +A G G +DV+ S LW N+ F+ N
Sbjct: 1303 -RAVSALGNAYFGSGSGPITLDDVECSGTESTLWQ------CRNRGWFSHN--------- 1346
Query: 582 WPDHGGCEHR-CVNTLGSYKCACDPGYELAADKKMCEVACGGFITKLNGTITSPGWPKEY 640
C HR + S P L + + +CGGF+++ +G +SP +P Y
Sbjct: 1347 ------CNHREDAGVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPGNY 1400
Query: 641 PTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVEVRSGLSPDAKLHGRFCGSETP 700
P N CVW + YR+++ F +LEG C YD++EV G + L R C
Sbjct: 1401 PNNAKCVWDIEVQNNYRVTVIFRDVQLEGG--CNYDYIEVFDGPYRSSPLIARVCDGARG 1458
Query: 701 EVITSQSNNMRVEFKSDNTVSKRGFRAHFFS 731
TS SN M + F SD+++++RGFRA ++S
Sbjct: 1459 S-FTSSSNFMSIRFISDHSITRRGFRAEYYS 1488
Score = 94.0 bits (232), Expect = 6e-19
Identities = 51/172 (29%), Positives = 86/172 (50%), Gaps = 9/172 (5%)
Query: 620 CGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVE 679
CGGF+ +GT +SP +P YP N CVW++ + YRI+L F +LE + C +D+VE
Sbjct: 1138 CGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVE 1197
Query: 680 VRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECA-- 737
+ G + L G+ C ++T ++ TS N M + F+SD + GF A + S +
Sbjct: 1198 IFDGSLNSSLLLGKIC-NDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDATLR 1256
Query: 738 -----KDNGGCQHEC-VNTFGSYLCRCRNGYWLHENGHDCKEAGCAHKISSV 783
G C + G++ C + + + E C++ GC +S++
Sbjct: 1257 LVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSAL 1308
Score = 87.0 bits (214), Expect = 8e-17
Identities = 51/182 (28%), Positives = 87/182 (47%), Gaps = 9/182 (4%)
Query: 462 ATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDY 521
+ CGG + +G SP+YP Y + +CVW I V+ G+ + L F ++E H +C++DY
Sbjct: 1136 SNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDY 1195
Query: 522 LEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECS 581
+E+ DG S L+G C + + SS NR+ + F SD S GF A + + +
Sbjct: 1196 VEIFDGSLNSSLLLGKICN-DTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDAT 1254
Query: 582 W------PDHGGCEHRC-VNTLGSYKCACDPGYELAADKKMC-EVACGGFITKLNGTITS 633
+G C R + G++ CD + + + +C ++ CG ++ L
Sbjct: 1255 LRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFG 1314
Query: 634 PG 635
G
Sbjct: 1315 SG 1316
Score = 81.3 bits (199), Expect = 4e-15
Identities = 49/163 (30%), Positives = 78/163 (47%), Gaps = 29/163 (17%)
Query: 746 ECVNTFGSYLCRCRNGYWLHENGHDCKEAG-------------------------CAHKI 780
EC T S L +CRN W N + ++AG C +
Sbjct: 1326 ECSGT-ESTLWQCRNRGWFSHNCNHREDAGVICSGNHLSTPAPFLNITRPNTDYSCGGFL 1384
Query: 781 SSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMYDGP 840
S G +SP +P YP+ +C W+I +RV + F + ++E C YD++E++DGP
Sbjct: 1385 SQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLE--GGCNYDYIEVFDGP 1442
Query: 841 DSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQA 883
+P++ R C + T +S + M +RF SD S+ R+GF+A
Sbjct: 1443 YRSSPLIARVCDGARGSFT-SSSNFMSIRFISDHSITRRGFRA 1484
Score = 80.1 bits (196), Expect = 1e-14
Identities = 36/114 (31%), Positives = 66/114 (57%), Gaps = 1/114 (0%)
Query: 774 AGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDH 833
+ C + GT +SP++P YP+ +C W I +G+R+ L F+ ++E H C++D+
Sbjct: 1136 SNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDY 1195
Query: 834 LEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQAVHST 887
+E++DG + + +LG+ C + T +S + M + F SD S Q GF A +++
Sbjct: 1196 VEIFDGSLNSSLLLGKICNDTRQIFT-SSYNRMTIHFRSDISFQNTGFLAWYNS 1248
Score = 75.1 bits (183), Expect = 3e-13
Identities = 44/125 (35%), Positives = 68/125 (54%), Gaps = 7/125 (5%)
Query: 889 CGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGY 948
CGG L Q +S + F NYP+ A+C W I ++ Y V + FR +V+ E C Y
Sbjct: 1380 CGGFLS---QPSGDFS-SPFYPGNYPNNAKCVWDIEVQNNYRVTVIFR--DVQLEGGCNY 1433
Query: 949 DYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARYTSTKFQ 1008
DY+E +DG S+P + R C G S+ + + IRF +D +I ++GF A Y S+
Sbjct: 1434 DYIEVFDGPYRSSPLIARVC-DGARGSFTSSSNFMSIRFISDHSITRRGFRAEYYSSPSN 1492
Query: 1009 DALHM 1013
D+ ++
Sbjct: 1493 DSTNL 1497
Score = 74.3 bits (181), Expect = 5e-13
Identities = 40/118 (33%), Positives = 63/118 (53%), Gaps = 3/118 (2%)
Query: 350 ACGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYV 409
+CG L +G+FS+P +P YP+ + CVW I V ++ + F + L C YDY+
Sbjct: 1379 SCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGG--CNYDYI 1436
Query: 410 EVRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEATCGGD 467
EV DG +R +PL+ R C D S+ + + + F S +I +GF A Y ++ D
Sbjct: 1437 EVFDGPYRSSPLIARVC-DGARGSFTSSSNFMSIRFISDHSITRRGFRAEYYSSPSND 1493
Score = 65.1 bits (157), Expect = 3e-10
Identities = 39/120 (32%), Positives = 61/120 (50%), Gaps = 7/120 (5%)
Query: 886 STECGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEAD 945
S+ CGG L T S+ + YP+ A+C W I GY + L F ++E +
Sbjct: 1135 SSNCGGFLFYASGTFSSPSYPAY----YPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHN 1190
Query: 946 CGYDYMEAYDGYDSSAPRLGRFCGSGPLEEIY-SAGDSLMIRFRTDDTINKKGFHARYTS 1004
C +DY+E +DG +S+ LG+ C +I+ S+ + + I FR+D + GF A Y S
Sbjct: 1191 CSFDYVEIFDGSLNSSLLLGKICND--TRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNS 1248
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.136 0.434
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,400,223
Number of Sequences: 37866
Number of extensions: 2101992
Number of successful extensions: 8843
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 189
Number of HSP's successfully gapped in prelim test: 44
Number of HSP's that attempted gapping in prelim test: 5170
Number of HSP's gapped (non-prelim): 2453
length of query: 1015
length of database: 18,247,518
effective HSP length: 112
effective length of query: 903
effective length of database: 14,006,526
effective search space: 12647892978
effective search space used: 12647892978
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.