Guide to the Human Genome
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Search of human proteins with 6912530

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|6912530 transmembrane 4 superfamily member 15 [Homo sapiens]
         (294 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|6912530 transmembrane 4 superfamily member 15 [Homo sapiens]       603   e-173
gi|30425534 tetraspanin 33 [Homo sapiens]                             196   2e-50
gi|21264583 transmembrane 4 superfamily member 9 [Homo sapiens]       168   5e-42
gi|50511934 transmembrane 4 superfamily member 17 isoform b [Hom...   167   8e-42
gi|54859560 transmembrane 4 superfamily member 17 isoform a [Hom...   164   1e-40
gi|54859505 transmembrane 4 superfamily member 17 isoform c [Hom...   163   1e-40
gi|190194420 tetraspanin 14 isoform 1 [Homo sapiens]                  157   8e-39
gi|119120834 tetraspanin 10 [Homo sapiens]                            123   2e-28
gi|21265104 tetraspanin 7 [Homo sapiens]                              103   2e-22
gi|5729941 tetraspanin 9 [Homo sapiens]                               102   3e-22
gi|4502679 CD63 antigen isoform A [Homo sapiens]                      101   7e-22
gi|122937466 tetraspanin 11 [Homo sapiens]                            100   2e-21
gi|4507541 transmembrane 4 superfamily member 6 [Homo sapiens]        100   2e-21
gi|87159824 CD151 antigen [Homo sapiens]                               97   2e-20
gi|87159822 CD151 antigen [Homo sapiens]                               97   2e-20
gi|21237751 CD151 antigen [Homo sapiens]                               97   2e-20
gi|21237748 CD151 antigen [Homo sapiens]                               97   2e-20
gi|91199546 CD63 antigen isoform B [Homo sapiens]                      97   2e-20
gi|68800005 tetraspanin 4 isoform a [Homo sapiens]                     85   7e-17
gi|4507543 tetraspanin 4 isoform a [Homo sapiens]                      85   7e-17
gi|68800018 tetraspanin 4 isoform a [Homo sapiens]                     85   7e-17
gi|68800024 tetraspanin 4 isoform a [Homo sapiens]                     85   7e-17
gi|68800011 tetraspanin 4 isoform a [Homo sapiens]                     85   7e-17
gi|68799997 tetraspanin 4 isoform a [Homo sapiens]                     85   7e-17
gi|21264578 tetraspan 1 [Homo sapiens]                                 82   4e-16
gi|190341022 tetraspanin 14 isoform 2 [Homo sapiens]                   78   1e-14
gi|10834972 CD53 antigen [Homo sapiens]                                75   5e-14
gi|91106727 CD53 antigen [Homo sapiens]                                75   5e-14
gi|5032201 transmembrane 4 superfamily member 8 isoform 1 [Homo ...    74   2e-13
gi|4504813 CD82 antigen isoform 1 [Homo sapiens]                       73   3e-13

>gi|6912530 transmembrane 4 superfamily member 15 [Homo sapiens]
          Length = 294

 Score =  603 bits (1556), Expect = e-173
 Identities = 294/294 (100%), Positives = 294/294 (100%)

Query: 1   MPRGDSEQVRYCARFSYLWLKFSLIIYSTVFWLIGALVLSVGIYAEVERQKYKTLESAFL 60
           MPRGDSEQVRYCARFSYLWLKFSLIIYSTVFWLIGALVLSVGIYAEVERQKYKTLESAFL
Sbjct: 1   MPRGDSEQVRYCARFSYLWLKFSLIIYSTVFWLIGALVLSVGIYAEVERQKYKTLESAFL 60

Query: 61  APAIILILLGVVMFMVSFIGVLASLRDNLYLLQAFMYILGICLIMELIGGVVALTFRNQT 120
           APAIILILLGVVMFMVSFIGVLASLRDNLYLLQAFMYILGICLIMELIGGVVALTFRNQT
Sbjct: 61  APAIILILLGVVMFMVSFIGVLASLRDNLYLLQAFMYILGICLIMELIGGVVALTFRNQT 120

Query: 121 IDFLNDNIRRGIENYYDDLDFKNIMDFVQKKFKCCGGEDYRDWSKNQYHDCSAPGPLACG 180
           IDFLNDNIRRGIENYYDDLDFKNIMDFVQKKFKCCGGEDYRDWSKNQYHDCSAPGPLACG
Sbjct: 121 IDFLNDNIRRGIENYYDDLDFKNIMDFVQKKFKCCGGEDYRDWSKNQYHDCSAPGPLACG 180

Query: 181 VPYTCCIRNTTEVVNTMCGYKTIDKERFSVQDVIYVRGCTNAVIIWFMDNYTIMAGILLG 240
           VPYTCCIRNTTEVVNTMCGYKTIDKERFSVQDVIYVRGCTNAVIIWFMDNYTIMAGILLG
Sbjct: 181 VPYTCCIRNTTEVVNTMCGYKTIDKERFSVQDVIYVRGCTNAVIIWFMDNYTIMAGILLG 240

Query: 241 ILLPQFLGVLLTLLYITRVEDIIMEHSVTDGLLGPGAKPSVEAAGTGCCLCYPN 294
           ILLPQFLGVLLTLLYITRVEDIIMEHSVTDGLLGPGAKPSVEAAGTGCCLCYPN
Sbjct: 241 ILLPQFLGVLLTLLYITRVEDIIMEHSVTDGLLGPGAKPSVEAAGTGCCLCYPN 294


>gi|30425534 tetraspanin 33 [Homo sapiens]
          Length = 283

 Score =  196 bits (499), Expect = 2e-50
 Identities = 89/247 (36%), Positives = 151/247 (61%), Gaps = 3/247 (1%)

Query: 20  LKFSLIIYSTVFWLIGALVLSVGIYAEVERQKYKTLESAFLAPAIILILLGVVMFMVSFI 79
           +K+ L  ++ +FW+I  ++++VG+YA + +     L    + PAI+LI++GV+MF+++F 
Sbjct: 22  VKYLLFFFNMLFWVISMVMVAVGVYARLMKHAEAALACLAVDPAILLIVVGVLMFLLTFC 81

Query: 80  GVLASLRDNLYLLQAFMYILGICLIMELIGGVVALTFRNQTIDFLNDNIRRGIENYYDDL 139
           G + SLR+N+ LLQ F   L    +++L  G++   F ++    +++ I   I +Y DDL
Sbjct: 82  GCIGSLRENICLLQTFSLCLTAVFLLQLAAGILGFVFSDKARGKVSEIINNAIVHYRDDL 141

Query: 140 DFKNIMDFVQKKFKCCGGEDYRDWSKNQYHDCSAPGPL--ACGVPYTCCIRNTTE-VVNT 196
           D +N++DF QKKF CCGG  Y+DWS+N Y +CS   P    C VPY+CC+    + V+NT
Sbjct: 142 DLQNLIDFGQKKFSCCGGISYKDWSQNMYFNCSEDNPSRERCSVPYSCCLPTPDQAVINT 201

Query: 197 MCGYKTIDKERFSVQDVIYVRGCTNAVIIWFMDNYTIMAGILLGILLPQFLGVLLTLLYI 256
           MCG      +      VIY  GC + ++ W   N  ++ G+ LG+ +PQ +G+LL+ + +
Sbjct: 202 MCGQGMQAFDYLEASKVIYTNGCIDKLVNWIHSNLFLLGGVALGLAIPQLVGILLSQILV 261

Query: 257 TRVEDII 263
            +++D I
Sbjct: 262 NQIKDQI 268


>gi|21264583 transmembrane 4 superfamily member 9 [Homo sapiens]
          Length = 268

 Score =  168 bits (426), Expect = 5e-42
 Identities = 87/250 (34%), Positives = 136/250 (54%), Gaps = 7/250 (2%)

Query: 20  LKFSLIIYSTVFWLIGALVLSVGIYAEVERQKYKTLESAF----LAPAIILILLGVVMFM 75
           +K+ +  ++ +FW +G   L +G++A  E+     + S        P  + +++G VMF+
Sbjct: 15  IKYFIFGFNVIFWFLGITFLGIGLWAWNEKGVLSNISSITDLGGFDPVWLFLVVGGVMFI 74

Query: 76  VSFIGVLASLRDNLYLLQAFMYILGICLIMELIGGVVALTFRNQTIDFLNDNIRRGIENY 135
           + F G + +LR+N +LL+ F   LGI   +EL  GV+A  F++   D L   I   I  Y
Sbjct: 75  LGFAGCIGALRENTFLLKFFSVFLGIIFFLELTAGVLAFVFKDWIKDQLYFFINNNIRAY 134

Query: 136 YDDLDFKNIMDFVQKKFKCCGGEDYRDWSKNQYHDC--SAPGPLACGVPYTCCIRNTTE- 192
            DD+D +N++DF Q+ ++CCG     DW+ N Y +C  S      CGVP++CC ++  E 
Sbjct: 135 RDDIDLQNLIDFTQEYWQCCGAFGADDWNLNIYFNCTDSNASRERCGVPFSCCTKDPAED 194

Query: 193 VVNTMCGYKTIDKERFSVQDVIYVRGCTNAVIIWFMDNYTIMAGILLGILLPQFLGVLLT 252
           V+NT CGY    K     Q VIY +GC      W  DN TI+AGI +GI L Q  G+ L 
Sbjct: 195 VINTQCGYDARQKPEVDQQIVIYTKGCVPQFEKWLQDNLTIVAGIFIGIALLQIFGICLA 254

Query: 253 LLYITRVEDI 262
              ++ +E +
Sbjct: 255 QNLVSDIEAV 264


>gi|50511934 transmembrane 4 superfamily member 17 isoform b [Homo
           sapiens]
          Length = 329

 Score =  167 bits (424), Expect = 8e-42
 Identities = 83/249 (33%), Positives = 140/249 (56%), Gaps = 7/249 (2%)

Query: 21  KFSLIIYSTVFWLIGALVLSVGIYAEVERQKYKTLESAF----LAPAIILILLGVVMFMV 76
           K+ L  ++ VFW++GAL L++G++A  E+     + +      L P  + +++G VM ++
Sbjct: 18  KYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGGLDPVWLFVVVGGVMSVL 77

Query: 77  SFIGVLASLRDNLYLLQAFMYILGICLIMELIGGVVALTFRNQTIDFLNDNIRRGIENYY 136
            F G + +LR+N +LL+ F   LG+   +EL  G++A  F++   D LN  I   ++ Y 
Sbjct: 78  GFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNNVKAYR 137

Query: 137 DDLDFKNIMDFVQKKFKCCGGEDYRDWSKNQYHDCS--APGPLACGVPYTCCIRNTTE-V 193
           DD+D +N++DF Q+ + CCG     DW+ N Y +C+   P    CGVP++CC+R+  E V
Sbjct: 138 DDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCCVRDPAEDV 197

Query: 194 VNTMCGYKTIDKERFSVQDVIYVRGCTNAVIIWFMDNYTIMAGILLGILLPQFLGVLLTL 253
           +NT CGY    K     Q  I+ +GC      W  DN  ++AG+ +GI L Q  G+ L  
Sbjct: 198 LNTQCGYDVRLKLELEQQGFIHTKGCVGQFEKWLQDNLIVVAGVFMGIALLQIFGICLAQ 257

Query: 254 LYITRVEDI 262
             ++ ++ +
Sbjct: 258 NLVSDIKAV 266


>gi|54859560 transmembrane 4 superfamily member 17 isoform a [Homo
           sapiens]
          Length = 332

 Score =  164 bits (414), Expect = 1e-40
 Identities = 82/252 (32%), Positives = 141/252 (55%), Gaps = 10/252 (3%)

Query: 21  KFSLIIYSTVFWLIGALVLSVGIYAEVERQKYKTLESAF----LAPAIILILLGVVMFMV 76
           K+ L  ++ VFW++GAL L++G++A  E+     + +      L P  + +++G VM ++
Sbjct: 18  KYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGGLDPVWLFVVVGGVMSVL 77

Query: 77  SFIGVLASLRDNLYLLQAFMYILGICLIMELIGGVVALTFRNQTIDFLNDNIRRGIENYY 136
            F G + +LR+N +LL+ F   LG+   +EL  G++A  F++   D LN  I   ++ Y 
Sbjct: 78  GFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNNVKAYR 137

Query: 137 DDLDFKNIMDFVQKKFKCCGGEDYRDWSKNQYHDCS--APGPLACGVPYTCCIRNTTE-V 193
           DD+D +N++DF Q+ + CCG     DW+ N Y +C+   P    CGVP++CC+R+  E V
Sbjct: 138 DDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCCVRDPAEDV 197

Query: 194 VNTMCGYKT---IDKERFSVQDVIYVRGCTNAVIIWFMDNYTIMAGILLGILLPQFLGVL 250
           +NT CGY     + +     Q  I+ +GC      W  DN  ++AG+ +GI L Q  G+ 
Sbjct: 198 LNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLIVVAGVFMGIALLQIFGIC 257

Query: 251 LTLLYITRVEDI 262
           L    ++ ++ +
Sbjct: 258 LAQNLVSDIKAV 269


>gi|54859505 transmembrane 4 superfamily member 17 isoform c [Homo
           sapiens]
          Length = 266

 Score =  163 bits (413), Expect = 1e-40
 Identities = 82/241 (34%), Positives = 136/241 (56%), Gaps = 10/241 (4%)

Query: 21  KFSLIIYSTVFWLIGALVLSVGIYAEVERQKYKTLESAF----LAPAIILILLGVVMFMV 76
           K+ L  ++ VFW++GAL L++G++A  E+     + +      L P  + +++G VM ++
Sbjct: 18  KYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGGLDPVWLFVVVGGVMSVL 77

Query: 77  SFIGVLASLRDNLYLLQAFMYILGICLIMELIGGVVALTFRNQTIDFLNDNIRRGIENYY 136
            F G + +LR+N +LL+ F   LG+   +EL  G++A  F++   D LN  I   ++ Y 
Sbjct: 78  GFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNNVKAYR 137

Query: 137 DDLDFKNIMDFVQKKFKCCGGEDYRDWSKNQYHDCS--APGPLACGVPYTCCIRNTTE-V 193
           DD+D +N++DF Q+ + CCG     DW+ N Y +C+   P    CGVP++CC+R+  E V
Sbjct: 138 DDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCCVRDPAEDV 197

Query: 194 VNTMCGYKT---IDKERFSVQDVIYVRGCTNAVIIWFMDNYTIMAGILLGILLPQFLGVL 250
           +NT CGY     + +     Q  I+ +GC      W  DN  ++AG+ +GI L Q  G+ 
Sbjct: 198 LNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLIVVAGVFMGIALLQIFGIC 257

Query: 251 L 251
           L
Sbjct: 258 L 258


>gi|190194420 tetraspanin 14 isoform 1 [Homo sapiens]
          Length = 270

 Score =  157 bits (398), Expect = 8e-39
 Identities = 82/255 (32%), Positives = 135/255 (52%), Gaps = 7/255 (2%)

Query: 19  WLKFSLIIYSTVFWLIGALVLSVGIYAEVERQKYKTLESAF----LAPAIILILLGVVMF 74
           W K+ L  Y+ +FWL G + L VG++A  E+     L        + P ++++++GVVMF
Sbjct: 14  WYKYLLFSYNIIFWLAGVVFLGVGLWAWSEKGVLSDLTKVTRMHGIDPVVLVLMVGVVMF 73

Query: 75  MVSFIGVLASLRDNLYLLQAFMYILGICLIMELIGGVVALTFRNQTIDFLNDNIRRGIEN 134
            + F G + +LR+N+ LL  F   + +   +EL   V+A  F++   D   +     I++
Sbjct: 74  TLGFAGCVGALRENICLLNFFCGTIVLIFFLELAVAVLAFLFQDWVRDRFREFFESNIKS 133

Query: 135 YYDDLDFKNIMDFVQKKFKCCGGEDYRDWSKNQYHDCSAP--GPLACGVPYTCCIRNTTE 192
           Y DD+D +N++D +QK  +CCG     DW  N Y +CS        CGVP++CC+ +  +
Sbjct: 134 YRDDIDLQNLIDSLQKANQCCGAYGPEDWDLNVYFNCSGASYSREKCGVPFSCCVPDPAQ 193

Query: 193 -VVNTMCGYKTIDKERFSVQDVIYVRGCTNAVIIWFMDNYTIMAGILLGILLPQFLGVLL 251
            VVNT CGY    + +    + I+ +GC  A+  W   N  I+AG+ + I L Q  G+ L
Sbjct: 194 KVVNTQCGYDVRIQLKSKWDESIFTKGCIQALESWLPRNIYIVAGVFIAISLLQIFGIFL 253

Query: 252 TLLYITRVEDIIMEH 266
               I+ +E +   H
Sbjct: 254 ARTLISDIEAVKAGH 268


>gi|119120834 tetraspanin 10 [Homo sapiens]
          Length = 355

 Score =  123 bits (308), Expect = 2e-28
 Identities = 73/236 (30%), Positives = 119/236 (50%), Gaps = 4/236 (1%)

Query: 20  LKFSLIIYSTVFWLIGALVLSVGIYA-EVERQKYKTLESAFLA-PAIILILLGVVMFMVS 77
           +K+ + + +  F L+G L L++G++   V+      L     A P + L L G+V+  VS
Sbjct: 76  VKYLIFLSNFPFSLLGLLALAIGLWGLAVKGSLGSDLGGPLPADPMLGLALGGLVVSAVS 135

Query: 78  FIGVLASLRDNLYLLQAFMYILGICLIMELIGGVVALTFRNQTIDFLNDNIRRGIENYYD 137
             G L +L +N  LL+ F   +   L++E + G + +       D L   +R  I +Y D
Sbjct: 136 LAGYLGALCENTCLLRGFSGGILAFLVLEAVAGALVVALWGPLQDSLEHTLRVAIAHYQD 195

Query: 138 DLDFKNIMDFVQKKFKCCGGEDYRDWSKNQYHDCSAPGPLACGVPYTCCI--RNTTEVVN 195
           D D + ++D VQ   +CCG   Y+DW +N Y +CS+PG  AC +P +CCI  R     VN
Sbjct: 196 DPDLRFLLDQVQLGLRCCGAASYQDWQQNLYFNCSSPGVQACSLPASCCIDPREDGASVN 255

Query: 196 TMCGYKTIDKERFSVQDVIYVRGCTNAVIIWFMDNYTIMAGILLGILLPQFLGVLL 251
             CG+  +  +  + Q V+Y+ GC   +  W   N     G  + ++L Q   +LL
Sbjct: 256 DQCGFGVLRLDADAAQRVVYLEGCGPPLRRWLRANLAASGGYAIAVVLLQGAELLL 311


>gi|21265104 tetraspanin 7 [Homo sapiens]
          Length = 249

 Score =  103 bits (256), Expect = 2e-22
 Identities = 65/234 (27%), Positives = 114/234 (48%), Gaps = 17/234 (7%)

Query: 20  LKFSLIIYSTVFWLIGALVLSVGIYAEVERQKYKTL--ESAFLAPAIILILLGVVMFMVS 77
           LK  LIIYS VFW+ G ++L+VG++ ++    Y +L  E++  AP  +LI  G  + +  
Sbjct: 15  LKTLLIIYSFVFWITGVILLAVGVWGKLTLGTYISLIAENSTNAP-YVLIGTGTTIVVFG 73

Query: 78  FIGVLASLRDNLYLLQAFMYILGICLIMELIGGVVALTFRNQTIDFLNDNIRRGIENYYD 137
             G  A+ R + ++L+ +   L +  + EL+ G+    FR++  D         ++ Y  
Sbjct: 74  LFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIKDTFLRTYTDAMQTYNG 133

Query: 138 DLDFKNIMDFVQKKFKCCGGEDYRDWSKNQYHDCSAPGPLACGVPYTCCIRNTTEVVNTM 197
           + +    +D VQ+   CCG ++Y +WS + Y        L  G+P +CC+  T       
Sbjct: 134 NDERSRAVDHVQRSLSCCGVQNYTNWSTSPYF-------LEHGIPPSCCMNETD------ 180

Query: 198 CGYKTIDKERFSVQDVIYVRGCTNAVIIWFMDNYTIMAGILLGILLPQFLGVLL 251
           C  + +     +   V   +GC + V  +   N  I+AG+  GI   Q +G+LL
Sbjct: 181 CNPQDLHNLTVAATKV-NQKGCYDLVTSFMETNMGIIAGVAFGIAFSQLIGMLL 233


>gi|5729941 tetraspanin 9 [Homo sapiens]
          Length = 239

 Score =  102 bits (255), Expect = 3e-22
 Identities = 63/245 (25%), Positives = 122/245 (49%), Gaps = 26/245 (10%)

Query: 13  ARFSYLWLKFSLIIYSTVFWLIGALVLSVGIYAEVERQKYKTLESAF--LAPAIILILLG 70
           AR     LK+ + +++ +FWL G  +L VGI+  V +  + T   +F  L+ A ++I +G
Sbjct: 2   ARGCLCCLKYMMFLFNLIFWLCGCGLLGVGIWLSVSQGNFATFSPSFPSLSAANLVIAIG 61

Query: 71  VVMFMVSFIGVLASLRDNLYLLQAFMYILGICLIMELIGGVVALTFRNQTIDFLNDNIRR 130
            ++ +  F+G L ++++N  LL +F  +L + L+ ELI  ++   + ++  +    +++ 
Sbjct: 62  TIVMVTGFLGCLGAIKENKCLLLSFFIVLLVILLAELILLILFFVYMDKVNENAKKDLKE 121

Query: 131 GIENYY--DDLDFKNIMDFVQKKFKCCGGEDYRDWSKNQYHDCSAPGPLACGVPYTCCIR 188
           G+  Y+  +++  KN  + +Q + +CCG  DY DW          P      VP  CC+ 
Sbjct: 122 GLLLYHTENNVGLKNAWNIIQAEMRCCGVTDYTDW---------YPVLGENTVPDRCCME 172

Query: 189 NTTEVVNTMCGYKTIDKERFSVQDVIYVRGCTNAVIIWFMDNYTIMAGILLGILLPQFLG 248
           N+       CG         +    ++  GC   V +WF DN  ++  + + IL+ Q LG
Sbjct: 173 NSQG-----CGR--------NATTPLWRTGCYEKVKMWFDDNKHVLGTVGMCILIMQILG 219

Query: 249 VLLTL 253
           +  ++
Sbjct: 220 MAFSM 224


>gi|4502679 CD63 antigen isoform A [Homo sapiens]
          Length = 238

 Score =  101 bits (252), Expect = 7e-22
 Identities = 62/242 (25%), Positives = 110/242 (45%), Gaps = 22/242 (9%)

Query: 20  LKFSLIIYSTVFWL--IGALVLSVGIYAEVERQKYKTLESAFLAPAIILILLGVVMFMVS 77
           +KF L +    F    +G + + VG    + +   +      L P +++I +GV +F+V+
Sbjct: 10  VKFLLYVLLLAFCACAVGLIAVGVGAQLVLSQTIIQGATPGSLLP-VVIIAVGVFLFLVA 68

Query: 78  FIGVLASLRDNLYLLQAFMYILGICLIMELIGGVVALTFRNQTIDFLNDNIRRGIENYYD 137
           F+G   + ++N  L+  F   L + +++E+   +    FR++ +   N+N R+ +ENY  
Sbjct: 69  FVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNFRQQMENYPK 128

Query: 138 DLDFKNIMDFVQKKFKCCGGEDYRDWSKNQYHDCSAPGPLACGVPYTCCIRNTTEVVNTM 197
           +    +I+D +Q  FKCCG  +Y DW K        P      VP +CCI      V   
Sbjct: 129 NNHTASILDRMQADFKCCGAANYTDWEK-------IPSMSKNRVPDSCCIN-----VTVG 176

Query: 198 CGYKTIDKERFSVQDVIYVRGCTNAVIIWFMDNYTIMAGILLGILLPQFLGVLLTLLYIT 257
           CG    +K        I+  GC   +  W   N  ++A   LGI   + LG++     + 
Sbjct: 177 CGINFNEK-------AIHKEGCVEKIGGWLRKNVLVVAAAALGIAFVEVLGIVFACCLVK 229

Query: 258 RV 259
            +
Sbjct: 230 SI 231


>gi|122937466 tetraspanin 11 [Homo sapiens]
          Length = 253

 Score =  100 bits (249), Expect = 2e-21
 Identities = 70/249 (28%), Positives = 119/249 (47%), Gaps = 19/249 (7%)

Query: 18  LWLKFSLIIYSTVFWLIGALVLSVGIYAEVERQKYKTL--ESAFLAPAIILILLGVVMFM 75
           ++LK+ L +++  FW+ GA VL+VGI+  VE+  Y ++   S F A A ILI  GV++ +
Sbjct: 14  IYLKYLLFVFNFFFWVGGAAVLAVGIWTLVEKSGYLSVLASSTFAASAYILIFAGVLVMV 73

Query: 76  VSFIGVLASLRDNLYLLQAFMYILGICLIMELIGGVVALTFRNQTIDFLNDNIRRGIENY 135
             F+G  A L +    L  +  +L +  ++EL+ GV+A  +  +  D L  ++ R +   
Sbjct: 74  TGFLGFGAILWERKGCLSTYFCLLLVIFLVELVAGVLAHVYYQRLSDELKQHLNRTLAEN 133

Query: 136 YDDLDFKNI---MDFVQKKFKCCGGEDYRDWSKNQYHDC-SAPGPLACGVPYTCCIRNTT 191
           Y       I   +D +Q+ FKCCG     DW  + Y     A G     VP +CC     
Sbjct: 134 YGQPGATQITASVDRLQQDFKCCGSNSSADWQHSTYILLREAEGR---QVPDSCC----- 185

Query: 192 EVVNTMCGYKTIDKERFSVQDVIYVRGCTNAVIIWFMDNYTIMAGILLGILLPQFLGVLL 251
           + V   CG +      + V+      GC   +  +  D+  +M  + +G+   Q  G++L
Sbjct: 186 KTVVVRCGQRAHPSNIYKVEG-----GCLTKLEQFLADHLLLMGAVGIGVACLQICGMVL 240

Query: 252 TLLYITRVE 260
           T     R++
Sbjct: 241 TCCLHQRLQ 249


>gi|4507541 transmembrane 4 superfamily member 6 [Homo sapiens]
          Length = 245

 Score =  100 bits (249), Expect = 2e-21
 Identities = 62/234 (26%), Positives = 110/234 (47%), Gaps = 25/234 (10%)

Query: 21  KFSLIIYSTVFWLIGALVLSVGIYAEVERQKYKTL--ESAFLAPAIILILLGVVMFMVSF 78
           K  L+IY+ +FW+ G ++L+VGI+ +V  + Y +L  E A   P  +LI  G V+ ++  
Sbjct: 18  KSVLLIYTFIFWITGVILLAVGIWGKVSLENYFSLLNEKATNVP-FVLIATGTVIILLGT 76

Query: 79  IGVLASLRDNLYLLQAFMYILGICLIMELIGGVVALTFRNQTIDFLNDNIRRGIENYYDD 138
            G  A+ R + ++L+ +   L +  ++EL+  +V   FR++  +   +N  + ++ Y   
Sbjct: 77  FGCFATCRASAWMLKLYAMFLTLVFLVELVAAIVGFVFRHEIKNSFKNNYEKALKQYNST 136

Query: 139 LDFK-NIMDFVQKKFKCCGGEDYRDWSKNQYHDCSAPGPLACGVPYTCCIRNTTEVVNTM 197
            D++ + +D +Q    CCG  DYRDW+   Y+          G P +CC           
Sbjct: 137 GDYRSHAVDKIQNTLHCCGVTDYRDWTDTNYYS-------EKGFPKSCC----------- 178

Query: 198 CGYKTIDKERFSVQDVIYVRGCTNAVIIWFMDNYTIMAGILLGILLPQFLGVLL 251
              K  D       D +   GC   V+        ++AGI  G+   Q +G+ L
Sbjct: 179 ---KLEDCTPQRDADKVNNEGCFIKVMTIIESEMGVVAGISFGVACFQLIGIFL 229


>gi|87159824 CD151 antigen [Homo sapiens]
          Length = 253

 Score = 97.1 bits (240), Expect = 2e-20
 Identities = 59/238 (24%), Positives = 115/238 (48%), Gaps = 17/238 (7%)

Query: 20  LKFSLIIYSTVFWLIGALVLSVGIYAEVERQKYKTL--ESAFLAPAIILILLGVVMFMVS 77
           LK+ L  Y+  FWL G  V++VGI+    +  Y +L     +LA A IL++ G V+ +  
Sbjct: 16  LKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLLASGTYLATAYILVVAGTVVMVTG 75

Query: 78  FIGVLASLRDNLYLLQAFMYILGICLIMELIGGVVALTFRNQTIDFLNDNIRRGIENYYD 137
            +G  A+ ++   LL+ +  +L I  ++E+I G++A  +  Q    L +N++  +   Y 
Sbjct: 76  VLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNTELKENLKDTMTKRYH 135

Query: 138 DLDFKNI---MDFVQKKFKCCGGEDYRDWSKNQYHDCSAPGPLACGVPYTCCIRNTTEVV 194
               + +   +D +Q++F CCG  + +DW  +++      G     VP +CC     + V
Sbjct: 136 QPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIRSQEAGGRV--VPDSCC-----KTV 188

Query: 195 NTMCGYKTIDKERFSVQDVIYVRGCTNAVIIWFMDNYTIMAGILLGILLPQFLGVLLT 252
             +CG +      + V+      GC   +  +  ++  ++  + +GI   Q  G++ T
Sbjct: 189 VALCGQRDHASNIYKVEG-----GCITKLETFIQEHLRVIGAVGIGIACVQVFGMIFT 241


>gi|87159822 CD151 antigen [Homo sapiens]
          Length = 253

 Score = 97.1 bits (240), Expect = 2e-20
 Identities = 59/238 (24%), Positives = 115/238 (48%), Gaps = 17/238 (7%)

Query: 20  LKFSLIIYSTVFWLIGALVLSVGIYAEVERQKYKTL--ESAFLAPAIILILLGVVMFMVS 77
           LK+ L  Y+  FWL G  V++VGI+    +  Y +L     +LA A IL++ G V+ +  
Sbjct: 16  LKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLLASGTYLATAYILVVAGTVVMVTG 75

Query: 78  FIGVLASLRDNLYLLQAFMYILGICLIMELIGGVVALTFRNQTIDFLNDNIRRGIENYYD 137
            +G  A+ ++   LL+ +  +L I  ++E+I G++A  +  Q    L +N++  +   Y 
Sbjct: 76  VLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNTELKENLKDTMTKRYH 135

Query: 138 DLDFKNI---MDFVQKKFKCCGGEDYRDWSKNQYHDCSAPGPLACGVPYTCCIRNTTEVV 194
               + +   +D +Q++F CCG  + +DW  +++      G     VP +CC     + V
Sbjct: 136 QPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIRSQEAGGRV--VPDSCC-----KTV 188

Query: 195 NTMCGYKTIDKERFSVQDVIYVRGCTNAVIIWFMDNYTIMAGILLGILLPQFLGVLLT 252
             +CG +      + V+      GC   +  +  ++  ++  + +GI   Q  G++ T
Sbjct: 189 VALCGQRDHASNIYKVEG-----GCITKLETFIQEHLRVIGAVGIGIACVQVFGMIFT 241


>gi|21237751 CD151 antigen [Homo sapiens]
          Length = 253

 Score = 97.1 bits (240), Expect = 2e-20
 Identities = 59/238 (24%), Positives = 115/238 (48%), Gaps = 17/238 (7%)

Query: 20  LKFSLIIYSTVFWLIGALVLSVGIYAEVERQKYKTL--ESAFLAPAIILILLGVVMFMVS 77
           LK+ L  Y+  FWL G  V++VGI+    +  Y +L     +LA A IL++ G V+ +  
Sbjct: 16  LKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLLASGTYLATAYILVVAGTVVMVTG 75

Query: 78  FIGVLASLRDNLYLLQAFMYILGICLIMELIGGVVALTFRNQTIDFLNDNIRRGIENYYD 137
            +G  A+ ++   LL+ +  +L I  ++E+I G++A  +  Q    L +N++  +   Y 
Sbjct: 76  VLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNTELKENLKDTMTKRYH 135

Query: 138 DLDFKNI---MDFVQKKFKCCGGEDYRDWSKNQYHDCSAPGPLACGVPYTCCIRNTTEVV 194
               + +   +D +Q++F CCG  + +DW  +++      G     VP +CC     + V
Sbjct: 136 QPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIRSQEAGGRV--VPDSCC-----KTV 188

Query: 195 NTMCGYKTIDKERFSVQDVIYVRGCTNAVIIWFMDNYTIMAGILLGILLPQFLGVLLT 252
             +CG +      + V+      GC   +  +  ++  ++  + +GI   Q  G++ T
Sbjct: 189 VALCGQRDHASNIYKVEG-----GCITKLETFIQEHLRVIGAVGIGIACVQVFGMIFT 241


>gi|21237748 CD151 antigen [Homo sapiens]
          Length = 253

 Score = 97.1 bits (240), Expect = 2e-20
 Identities = 59/238 (24%), Positives = 115/238 (48%), Gaps = 17/238 (7%)

Query: 20  LKFSLIIYSTVFWLIGALVLSVGIYAEVERQKYKTL--ESAFLAPAIILILLGVVMFMVS 77
           LK+ L  Y+  FWL G  V++VGI+    +  Y +L     +LA A IL++ G V+ +  
Sbjct: 16  LKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLLASGTYLATAYILVVAGTVVMVTG 75

Query: 78  FIGVLASLRDNLYLLQAFMYILGICLIMELIGGVVALTFRNQTIDFLNDNIRRGIENYYD 137
            +G  A+ ++   LL+ +  +L I  ++E+I G++A  +  Q    L +N++  +   Y 
Sbjct: 76  VLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNTELKENLKDTMTKRYH 135

Query: 138 DLDFKNI---MDFVQKKFKCCGGEDYRDWSKNQYHDCSAPGPLACGVPYTCCIRNTTEVV 194
               + +   +D +Q++F CCG  + +DW  +++      G     VP +CC     + V
Sbjct: 136 QPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIRSQEAGGRV--VPDSCC-----KTV 188

Query: 195 NTMCGYKTIDKERFSVQDVIYVRGCTNAVIIWFMDNYTIMAGILLGILLPQFLGVLLT 252
             +CG +      + V+      GC   +  +  ++  ++  + +GI   Q  G++ T
Sbjct: 189 VALCGQRDHASNIYKVEG-----GCITKLETFIQEHLRVIGAVGIGIACVQVFGMIFT 241


>gi|91199546 CD63 antigen isoform B [Homo sapiens]
          Length = 236

 Score = 96.7 bits (239), Expect = 2e-20
 Identities = 60/224 (26%), Positives = 103/224 (45%), Gaps = 22/224 (9%)

Query: 20  LKFSLIIYSTVFWL--IGALVLSVGIYAEVERQKYKTLESAFLAPAIILILLGVVMFMVS 77
           +KF L +    F    +G + + VG    + +   +      L P +++I +GV +F+V+
Sbjct: 10  VKFLLYVLLLAFCACAVGLIAVGVGAQLVLSQTIIQGATPGSLLP-VVIIAVGVFLFLVA 68

Query: 78  FIGVLASLRDNLYLLQAFMYILGICLIMELIGGVVALTFRNQTIDFLNDNIRRGIENYYD 137
           F+G   + ++N  L+  F   L + +++E+   +    FR++ +   N+N R+ +ENY  
Sbjct: 69  FVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNFRQQMENYPK 128

Query: 138 DLDFKNIMDFVQKKFKCCGGEDYRDWSKNQYHDCSAPGPLACGVPYTCCIRNTTEVVNTM 197
           +    +I+D +Q  FKCCG  +Y DW K        P      VP +CCI      V   
Sbjct: 129 NNHTASILDRMQADFKCCGAANYTDWEK-------IPSMSKNRVPDSCCIN-----VTVG 176

Query: 198 CGYKTIDKERFSVQDVIYVRGCTNAVIIWFMDNYTIMAGILLGI 241
           CG    +K        I+  GC   +  W   N  ++A   LGI
Sbjct: 177 CGINFNEK-------AIHKEGCVEKIGGWLRKNVLVVAAAALGI 213


>gi|68800005 tetraspanin 4 isoform a [Homo sapiens]
          Length = 238

 Score = 85.1 bits (209), Expect = 7e-17
 Identities = 57/244 (23%), Positives = 109/244 (44%), Gaps = 26/244 (10%)

Query: 20  LKFSLIIYSTVFWLIGALVLSVGIYAEVERQKYKTLESAF--LAPAIILILLGVVMFMVS 77
           +K+ +  ++ +FWL G  VL VGI+    +  + TL S+F  L+ A +LI+ G  +  + 
Sbjct: 9   VKYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATLSSSFPSLSAANLLIITGAFVMAIG 68

Query: 78  FIGVLASLRDNLYLLQAFMYILGICLIMELIGGVVALTFRNQTIDFLNDNIRRGIENY-- 135
           F+G L ++++N  LL  F  +L +  ++E    ++   + ++   +   ++++G+  Y  
Sbjct: 69  FVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDLKKGLHLYGT 128

Query: 136 YDDLDFKNIMDFVQKKFKCCGGEDYRDWSKNQYHDCSAPGPLACGVPYTCCIRNTTEVVN 195
             ++   N    +Q  F+CCG  +Y DW +  Y+        A  VP +CC+       +
Sbjct: 129 QGNVGLTNAWSIIQTDFRCCGVSNYTDWFE-VYN--------ATRVPDSCCLE-----FS 174

Query: 196 TMCGYKTIDKERFSVQDVIYVRGCTNAVIIWFMDNYTIMAGILLGILLPQFLGVLLTLLY 255
             CG               +   C   V +W  +N   +    L   L Q LG+   +  
Sbjct: 175 ESCG--------LHAPGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILGLTFAMTM 226

Query: 256 ITRV 259
             +V
Sbjct: 227 YCQV 230


>gi|4507543 tetraspanin 4 isoform a [Homo sapiens]
          Length = 238

 Score = 85.1 bits (209), Expect = 7e-17
 Identities = 57/244 (23%), Positives = 109/244 (44%), Gaps = 26/244 (10%)

Query: 20  LKFSLIIYSTVFWLIGALVLSVGIYAEVERQKYKTLESAF--LAPAIILILLGVVMFMVS 77
           +K+ +  ++ +FWL G  VL VGI+    +  + TL S+F  L+ A +LI+ G  +  + 
Sbjct: 9   VKYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATLSSSFPSLSAANLLIITGAFVMAIG 68

Query: 78  FIGVLASLRDNLYLLQAFMYILGICLIMELIGGVVALTFRNQTIDFLNDNIRRGIENY-- 135
           F+G L ++++N  LL  F  +L +  ++E    ++   + ++   +   ++++G+  Y  
Sbjct: 69  FVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDLKKGLHLYGT 128

Query: 136 YDDLDFKNIMDFVQKKFKCCGGEDYRDWSKNQYHDCSAPGPLACGVPYTCCIRNTTEVVN 195
             ++   N    +Q  F+CCG  +Y DW +  Y+        A  VP +CC+       +
Sbjct: 129 QGNVGLTNAWSIIQTDFRCCGVSNYTDWFE-VYN--------ATRVPDSCCLE-----FS 174

Query: 196 TMCGYKTIDKERFSVQDVIYVRGCTNAVIIWFMDNYTIMAGILLGILLPQFLGVLLTLLY 255
             CG               +   C   V +W  +N   +    L   L Q LG+   +  
Sbjct: 175 ESCG--------LHAPGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILGLTFAMTM 226

Query: 256 ITRV 259
             +V
Sbjct: 227 YCQV 230


>gi|68800018 tetraspanin 4 isoform a [Homo sapiens]
          Length = 238

 Score = 85.1 bits (209), Expect = 7e-17
 Identities = 57/244 (23%), Positives = 109/244 (44%), Gaps = 26/244 (10%)

Query: 20  LKFSLIIYSTVFWLIGALVLSVGIYAEVERQKYKTLESAF--LAPAIILILLGVVMFMVS 77
           +K+ +  ++ +FWL G  VL VGI+    +  + TL S+F  L+ A +LI+ G  +  + 
Sbjct: 9   VKYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATLSSSFPSLSAANLLIITGAFVMAIG 68

Query: 78  FIGVLASLRDNLYLLQAFMYILGICLIMELIGGVVALTFRNQTIDFLNDNIRRGIENY-- 135
           F+G L ++++N  LL  F  +L +  ++E    ++   + ++   +   ++++G+  Y  
Sbjct: 69  FVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDLKKGLHLYGT 128

Query: 136 YDDLDFKNIMDFVQKKFKCCGGEDYRDWSKNQYHDCSAPGPLACGVPYTCCIRNTTEVVN 195
             ++   N    +Q  F+CCG  +Y DW +  Y+        A  VP +CC+       +
Sbjct: 129 QGNVGLTNAWSIIQTDFRCCGVSNYTDWFE-VYN--------ATRVPDSCCLE-----FS 174

Query: 196 TMCGYKTIDKERFSVQDVIYVRGCTNAVIIWFMDNYTIMAGILLGILLPQFLGVLLTLLY 255
             CG               +   C   V +W  +N   +    L   L Q LG+   +  
Sbjct: 175 ESCG--------LHAPGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILGLTFAMTM 226

Query: 256 ITRV 259
             +V
Sbjct: 227 YCQV 230


>gi|68800024 tetraspanin 4 isoform a [Homo sapiens]
          Length = 238

 Score = 85.1 bits (209), Expect = 7e-17
 Identities = 57/244 (23%), Positives = 109/244 (44%), Gaps = 26/244 (10%)

Query: 20  LKFSLIIYSTVFWLIGALVLSVGIYAEVERQKYKTLESAF--LAPAIILILLGVVMFMVS 77
           +K+ +  ++ +FWL G  VL VGI+    +  + TL S+F  L+ A +LI+ G  +  + 
Sbjct: 9   VKYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATLSSSFPSLSAANLLIITGAFVMAIG 68

Query: 78  FIGVLASLRDNLYLLQAFMYILGICLIMELIGGVVALTFRNQTIDFLNDNIRRGIENY-- 135
           F+G L ++++N  LL  F  +L +  ++E    ++   + ++   +   ++++G+  Y  
Sbjct: 69  FVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDLKKGLHLYGT 128

Query: 136 YDDLDFKNIMDFVQKKFKCCGGEDYRDWSKNQYHDCSAPGPLACGVPYTCCIRNTTEVVN 195
             ++   N    +Q  F+CCG  +Y DW +  Y+        A  VP +CC+       +
Sbjct: 129 QGNVGLTNAWSIIQTDFRCCGVSNYTDWFE-VYN--------ATRVPDSCCLE-----FS 174

Query: 196 TMCGYKTIDKERFSVQDVIYVRGCTNAVIIWFMDNYTIMAGILLGILLPQFLGVLLTLLY 255
             CG               +   C   V +W  +N   +    L   L Q LG+   +  
Sbjct: 175 ESCG--------LHAPGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILGLTFAMTM 226

Query: 256 ITRV 259
             +V
Sbjct: 227 YCQV 230


>gi|68800011 tetraspanin 4 isoform a [Homo sapiens]
          Length = 238

 Score = 85.1 bits (209), Expect = 7e-17
 Identities = 57/244 (23%), Positives = 109/244 (44%), Gaps = 26/244 (10%)

Query: 20  LKFSLIIYSTVFWLIGALVLSVGIYAEVERQKYKTLESAF--LAPAIILILLGVVMFMVS 77
           +K+ +  ++ +FWL G  VL VGI+    +  + TL S+F  L+ A +LI+ G  +  + 
Sbjct: 9   VKYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATLSSSFPSLSAANLLIITGAFVMAIG 68

Query: 78  FIGVLASLRDNLYLLQAFMYILGICLIMELIGGVVALTFRNQTIDFLNDNIRRGIENY-- 135
           F+G L ++++N  LL  F  +L +  ++E    ++   + ++   +   ++++G+  Y  
Sbjct: 69  FVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDLKKGLHLYGT 128

Query: 136 YDDLDFKNIMDFVQKKFKCCGGEDYRDWSKNQYHDCSAPGPLACGVPYTCCIRNTTEVVN 195
             ++   N    +Q  F+CCG  +Y DW +  Y+        A  VP +CC+       +
Sbjct: 129 QGNVGLTNAWSIIQTDFRCCGVSNYTDWFE-VYN--------ATRVPDSCCLE-----FS 174

Query: 196 TMCGYKTIDKERFSVQDVIYVRGCTNAVIIWFMDNYTIMAGILLGILLPQFLGVLLTLLY 255
             CG               +   C   V +W  +N   +    L   L Q LG+   +  
Sbjct: 175 ESCG--------LHAPGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILGLTFAMTM 226

Query: 256 ITRV 259
             +V
Sbjct: 227 YCQV 230


>gi|68799997 tetraspanin 4 isoform a [Homo sapiens]
          Length = 238

 Score = 85.1 bits (209), Expect = 7e-17
 Identities = 57/244 (23%), Positives = 109/244 (44%), Gaps = 26/244 (10%)

Query: 20  LKFSLIIYSTVFWLIGALVLSVGIYAEVERQKYKTLESAF--LAPAIILILLGVVMFMVS 77
           +K+ +  ++ +FWL G  VL VGI+    +  + TL S+F  L+ A +LI+ G  +  + 
Sbjct: 9   VKYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATLSSSFPSLSAANLLIITGAFVMAIG 68

Query: 78  FIGVLASLRDNLYLLQAFMYILGICLIMELIGGVVALTFRNQTIDFLNDNIRRGIENY-- 135
           F+G L ++++N  LL  F  +L +  ++E    ++   + ++   +   ++++G+  Y  
Sbjct: 69  FVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDLKKGLHLYGT 128

Query: 136 YDDLDFKNIMDFVQKKFKCCGGEDYRDWSKNQYHDCSAPGPLACGVPYTCCIRNTTEVVN 195
             ++   N    +Q  F+CCG  +Y DW +  Y+        A  VP +CC+       +
Sbjct: 129 QGNVGLTNAWSIIQTDFRCCGVSNYTDWFE-VYN--------ATRVPDSCCLE-----FS 174

Query: 196 TMCGYKTIDKERFSVQDVIYVRGCTNAVIIWFMDNYTIMAGILLGILLPQFLGVLLTLLY 255
             CG               +   C   V +W  +N   +    L   L Q LG+   +  
Sbjct: 175 ESCG--------LHAPGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILGLTFAMTM 226

Query: 256 ITRV 259
             +V
Sbjct: 227 YCQV 230


>gi|21264578 tetraspan 1 [Homo sapiens]
          Length = 241

 Score = 82.4 bits (202), Expect = 4e-16
 Identities = 58/233 (24%), Positives = 104/233 (44%), Gaps = 22/233 (9%)

Query: 17  YLWLKFSLIIYSTVFWLIGALVLSVGIYAEVERQKYKTLESAFLAPAI-------ILILL 69
           + ++K  +I+++ + +L GA +L+VGI+  ++   +  +     + A+        LI  
Sbjct: 4   FSFIKTMMILFNLLIFLCGAALLAVGIWVSIDGASFLKIFGPLSSSAMQFVNVGYFLIAA 63

Query: 70  GVVMFMVSFIGVLASLRDNLYLLQAFMYILGICLIMELIGGVVALTFRNQTIDFLNDNIR 129
           GVV+F + F+G   +  ++   L  F +IL +  I E+   VVAL +      FL   + 
Sbjct: 64  GVVVFALGFLGCYGAKTESKCALVTFFFILLLIFIAEVAAAVVALVYTTMAEHFLTLLVV 123

Query: 130 RGI-ENYYDDLDFKNIMDFVQKKFKCCGGEDYRDWSKNQYHDCSAPGPLACGVPYTCCIR 188
             I ++Y    DF  + +   K  KCCG  +Y D+  + Y   ++  P     P+ CC  
Sbjct: 124 PAIKKDYGSQEDFTQVWNTTMKGLKCCGFTNYTDFEDSPYFKENSAFP-----PF-CCND 177

Query: 189 NTTEVVNTMCGYKTIDKERFSVQDVIYVRGCTNAVIIWFMDNYTIMAGILLGI 241
           N T   N  C  +    ++        V GC N ++     N   + G+  GI
Sbjct: 178 NVTNTANETCTKQKAHDQK--------VEGCFNQLLYDIRTNAVTVGGVAAGI 222


>gi|190341022 tetraspanin 14 isoform 2 [Homo sapiens]
          Length = 147

 Score = 77.8 bits (190), Expect = 1e-14
 Identities = 39/117 (33%), Positives = 59/117 (50%), Gaps = 3/117 (2%)

Query: 153 KCCGGEDYRDWSKNQYHDCSAPGPLA--CGVPYTCCIRNTTE-VVNTMCGYKTIDKERFS 209
           +CCG     DW  N Y +CS        CGVP++CC+ +  + VVNT CGY    + +  
Sbjct: 29  QCCGAYGPEDWDLNVYFNCSGASYSREKCGVPFSCCVPDPAQKVVNTQCGYDVRIQLKSK 88

Query: 210 VQDVIYVRGCTNAVIIWFMDNYTIMAGILLGILLPQFLGVLLTLLYITRVEDIIMEH 266
             + I+ +GC  A+  W   N  I+AG+ + I L Q  G+ L    I+ +E +   H
Sbjct: 89  WDESIFTKGCIQALESWLPRNIYIVAGVFIAISLLQIFGIFLARTLISDIEAVKAGH 145


>gi|10834972 CD53 antigen [Homo sapiens]
          Length = 219

 Score = 75.5 bits (184), Expect = 5e-14
 Identities = 38/155 (24%), Positives = 75/155 (48%), Gaps = 5/155 (3%)

Query: 20  LKFSLIIYSTVFWLIGALVLSVGIYAEVERQ---KYKTLESAFLAPAIILILLGVVMFMV 76
           LK+ L  ++ +FW+ G  +L  GIY  +       +  L S  L    + +++G ++ +V
Sbjct: 9   LKYVLFFFNLLFWICGCCILGFGIYLLIHNNFGVLFHNLPSLTLGN--VFVIVGSIIMVV 66

Query: 77  SFIGVLASLRDNLYLLQAFMYILGICLIMELIGGVVALTFRNQTIDFLNDNIRRGIENYY 136
           +F+G + S+++N  LL +F  +L I L+ E+   ++   +  +  +++   +   I  Y+
Sbjct: 67  AFLGCMGSIKENKCLLMSFFILLLIILLAEVTLAILLFVYEQKLNEYVAKGLTDSIHRYH 126

Query: 137 DDLDFKNIMDFVQKKFKCCGGEDYRDWSKNQYHDC 171
            D   K   D +Q   +CCG     DW+      C
Sbjct: 127 SDNSTKAAWDSIQSFLQCCGINGTSDWTSGPPASC 161


>gi|91106727 CD53 antigen [Homo sapiens]
          Length = 219

 Score = 75.5 bits (184), Expect = 5e-14
 Identities = 38/155 (24%), Positives = 75/155 (48%), Gaps = 5/155 (3%)

Query: 20  LKFSLIIYSTVFWLIGALVLSVGIYAEVERQ---KYKTLESAFLAPAIILILLGVVMFMV 76
           LK+ L  ++ +FW+ G  +L  GIY  +       +  L S  L    + +++G ++ +V
Sbjct: 9   LKYVLFFFNLLFWICGCCILGFGIYLLIHNNFGVLFHNLPSLTLGN--VFVIVGSIIMVV 66

Query: 77  SFIGVLASLRDNLYLLQAFMYILGICLIMELIGGVVALTFRNQTIDFLNDNIRRGIENYY 136
           +F+G + S+++N  LL +F  +L I L+ E+   ++   +  +  +++   +   I  Y+
Sbjct: 67  AFLGCMGSIKENKCLLMSFFILLLIILLAEVTLAILLFVYEQKLNEYVAKGLTDSIHRYH 126

Query: 137 DDLDFKNIMDFVQKKFKCCGGEDYRDWSKNQYHDC 171
            D   K   D +Q   +CCG     DW+      C
Sbjct: 127 SDNSTKAAWDSIQSFLQCCGINGTSDWTSGPPASC 161


>gi|5032201 transmembrane 4 superfamily member 8 isoform 1 [Homo
           sapiens]
          Length = 253

 Score = 73.6 bits (179), Expect = 2e-13
 Identities = 56/246 (22%), Positives = 105/246 (42%), Gaps = 27/246 (10%)

Query: 21  KFSLIIYSTVFWLIGALVLSVGIYAEVERQKYKTL-ESAF-LAPAIILILLGVVMFMVSF 78
           K  L+  + +FW    ++  VG Y  +    Y    E  + L PA+++I +G ++F++  
Sbjct: 10  KTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIAVGALLFIIGL 69

Query: 79  IGVLASLRDNLYLLQAFMYILGICLIMELIGGVVALTFRNQTIDFLNDNIRRGIENYYDD 138
           IG  A++R++   L  F+ IL +  + E++  V+   +R +    + + + R I+  Y  
Sbjct: 70  IGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAK----VENEVDRSIQKVYKT 125

Query: 139 LDFKN------IMDFVQKKFKCCGGEDYRDWSKNQYHDCSAPGPLACGVPYTCCIRNTTE 192
            +  N       +D+VQ++  CCG  +Y DW    +   +        VP +CC R T  
Sbjct: 126 YNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQ----SVPLSCC-RETAS 180

Query: 193 VVNTMCGYKTIDKERFSVQDVIYVRGCTNAVIIWFMDNYTIMAGILLGILLPQFLGVLLT 252
             N    + +           +Y  GC   V+    +    +    L     Q LG+L  
Sbjct: 181 NCNGSLAHPS----------DLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCA 230

Query: 253 LLYITR 258
            + + R
Sbjct: 231 CIVLCR 236


>gi|4504813 CD82 antigen isoform 1 [Homo sapiens]
          Length = 267

 Score = 72.8 bits (177), Expect = 3e-13
 Identities = 51/246 (20%), Positives = 111/246 (45%), Gaps = 18/246 (7%)

Query: 21  KFSLIIYSTVFWLIGALVLSVGIYAEVERQKY----KTLESAFLAPAIILILLGVVMFMV 76
           K+ L +++ +F+++GA++L  G++   ++  +    +T  S+    A + I +G V  ++
Sbjct: 10  KYFLFLFNLIFFILGAVILGFGVWILADKSSFISVLQTSSSSLRMGAYVFIGVGAVTMLM 69

Query: 77  SFIGVLASLRDNLYLLQAFMYILGICLIMELIGGVVALTFRNQTIDFLNDNIRRGIENYY 136
            F+G + ++ +   LL  +   L + LI ++  G +      +    +   +   I +Y 
Sbjct: 70  GFLGCIGAVNEVRCLLGLYFAFLLLILIAQVTAGALFYFNMGKLKQEMGGIVTELIRDYN 129

Query: 137 DDLD--FKNIMDFVQKKFKCCGGEDYRDWSKNQYHDCSAPGPLACGVPYTCCIR----NT 190
              +   ++  D+VQ + KCCG   + +W+ N               P +C ++    N+
Sbjct: 130 SSREDSLQDAWDYVQAQVKCCGWVSFYNWTDN----AELMNRPEVTYPCSCEVKGEEDNS 185

Query: 191 TEVVNTMC---GYKTIDKERFSVQDVIYVRGCTNAVIIWFMDNYTIMAGILLGILLPQFL 247
             V    C   G +T           +Y  GC   V  W  +N  I+ G+ +G+ + + L
Sbjct: 186 LSVRKGFCEAPGNRT-QSGNHPEDWPVYQEGCMEKVQAWLQENLGIILGVGVGVAIIELL 244

Query: 248 GVLLTL 253
           G++L++
Sbjct: 245 GMVLSI 250


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.329    0.145    0.458 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,737,888
Number of Sequences: 37866
Number of extensions: 437820
Number of successful extensions: 1578
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 44
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 1449
Number of HSP's gapped (non-prelim): 69
length of query: 294
length of database: 18,247,518
effective HSP length: 101
effective length of query: 193
effective length of database: 14,423,052
effective search space: 2783649036
effective search space used: 2783649036
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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