BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|68226418 glucose transporter protein 10 isoform b [Homo sapiens] (499 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|68226418 glucose transporter protein 10 isoform b [Homo sapiens] 989 0.0 gi|68226420 glucose transporter protein 10 isoform c [Homo sapiens] 973 0.0 gi|190684655 glucose transporter protein 10 isoform a [Homo sapi... 971 0.0 gi|47933389 solute carrier family 2, member 9 protein isoform 2 ... 389 e-108 gi|47933387 solute carrier family 2, member 9 protein isoform 1 ... 389 e-108 gi|4507013 solute carrier family 2 (facilitated glucose/fructose... 389 e-108 gi|134053883 intestinal facilitative glucose transporter 7 [Homo... 374 e-103 gi|166795299 solute carrier family 2 (facilitated glucose transp... 320 2e-87 gi|4507011 glucose transporter 4 [Homo sapiens] 312 4e-85 gi|5902090 solute carrier family 2 (facilitated glucose transpor... 292 6e-79 gi|23592238 glucose transporter 14 [Homo sapiens] 284 1e-76 gi|4557851 solute carrier family 2 (facilitated glucose transpor... 253 2e-67 gi|207447703 solute carrier family 2 (facilitated glucose/fructo... 179 5e-45 gi|21361449 solute carrier family 2 (facilitated glucose transpo... 125 1e-28 gi|223029432 solute carrier family 2 (facilitated glucose transp... 123 4e-28 gi|223029430 solute carrier family 2 (facilitated glucose transp... 117 3e-26 gi|203098995 solute carrier family 2 (facilitated glucose transp... 93 5e-19 gi|21553331 solute carrier family 2 (facilitated glucose transpo... 87 4e-17 gi|13540547 solute carrier family 2 member 10 [Homo sapiens] 84 2e-16 gi|4506999 solute carrier family 22 member 1 isoform a [Homo sap... 61 2e-09 gi|170650643 solute carrier family 22, member 23 isoform a [Homo... 56 7e-08 gi|213021148 SVOP-like isoform 1 [Homo sapiens] 55 1e-07 gi|166064021 solute carrier family 22 (organic anion transporter... 54 3e-07 gi|4507001 solute carrier family 22 member 2 [Homo sapiens] 54 3e-07 gi|4507005 solute carrier family 22 member 5 [Homo sapiens] 53 7e-07 gi|7662270 synaptic vesicle protein 2B homolog [Homo sapiens] 53 7e-07 gi|216548223 synaptic vesicle glycoprotein 2 [Homo sapiens] 52 1e-06 gi|90669191 solute carrier family 22 member 7 isoform b [Homo sa... 52 2e-06 gi|24497497 solute carrier family 22 member 7 isoform a [Homo sa... 52 2e-06 gi|73695465 synaptic vesicle glycoprotein 2C [Homo sapiens] 49 1e-05 >gi|68226418 glucose transporter protein 10 isoform b [Homo sapiens] Length = 499 Score = 989 bits (2557), Expect = 0.0 Identities = 499/499 (100%), Positives = 499/499 (100%) Query: 1 MLHALLRSRMIQGRILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEP 60 MLHALLRSRMIQGRILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEP Sbjct: 1 MLHALLRSRMIQGRILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEP 60 Query: 61 LPDHLVLLMWSLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRK 120 LPDHLVLLMWSLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRK Sbjct: 61 LPDHLVLLMWSLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRK 120 Query: 121 AGSFEMIMLGRLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVG 180 AGSFEMIMLGRLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVG Sbjct: 121 AGSFEMIMLGRLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVG 180 Query: 181 LRELLGGPQAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSG 240 LRELLGGPQAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSG Sbjct: 181 LRELLGGPQAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSG 240 Query: 241 DLAGELEELEEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYAS 300 DLAGELEELEEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYAS Sbjct: 241 DLAGELEELEEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYAS 300 Query: 301 SVFRKAGVPEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTV 360 SVFRKAGVPEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTV Sbjct: 301 SVFRKAGVPEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTV 360 Query: 361 ALCLQSSFPWTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWI 420 ALCLQSSFPWTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWI Sbjct: 361 ALCLQSSFPWTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWI 420 Query: 421 MLILVGLGFPFIMEALSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLNFP 480 MLILVGLGFPFIMEALSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLNFP Sbjct: 421 MLILVGLGFPFIMEALSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLNFP 480 Query: 481 RRAQGPTWRSLEVIQSTEL 499 RRAQGPTWRSLEVIQSTEL Sbjct: 481 RRAQGPTWRSLEVIQSTEL 499 >gi|68226420 glucose transporter protein 10 isoform c [Homo sapiens] Length = 496 Score = 973 bits (2516), Expect = 0.0 Identities = 490/491 (99%), Positives = 491/491 (100%) Query: 9 RMIQGRILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDHLVLL 68 R+IQGRILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDHLVLL Sbjct: 6 RLIQGRILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDHLVLL 65 Query: 69 MWSLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIM 128 MWSLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIM Sbjct: 66 MWSLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIM 125 Query: 129 LGRLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGP 188 LGRLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGP Sbjct: 126 LGRLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGP 185 Query: 189 QAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGELEE 248 QAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGELEE Sbjct: 186 QAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGELEE 245 Query: 249 LEEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGV 308 LEEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGV Sbjct: 246 LEEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGV 305 Query: 309 PEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVALCLQSSF 368 PEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVALCLQSSF Sbjct: 306 PEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVALCLQSSF 365 Query: 369 PWTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGLG 428 PWTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGLG Sbjct: 366 PWTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGLG 425 Query: 429 FPFIMEALSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLNFPRRAQGPTW 488 FPFIMEALSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLNFPRRAQGPTW Sbjct: 426 FPFIMEALSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLNFPRRAQGPTW 485 Query: 489 RSLEVIQSTEL 499 RSLEVIQSTEL Sbjct: 486 RSLEVIQSTEL 496 >gi|190684655 glucose transporter protein 10 isoform a [Homo sapiens] Length = 503 Score = 971 bits (2511), Expect = 0.0 Identities = 493/499 (98%), Positives = 493/499 (98%), Gaps = 1/499 (0%) Query: 2 LHALLRSR-MIQGRILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEP 60 L LR R IQGRILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEP Sbjct: 5 LEPSLRPRTQIQGRILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEP 64 Query: 61 LPDHLVLLMWSLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRK 120 LPDHLVLLMWSLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRK Sbjct: 65 LPDHLVLLMWSLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRK 124 Query: 121 AGSFEMIMLGRLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVG 180 AGSFEMIMLGRLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVG Sbjct: 125 AGSFEMIMLGRLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVG 184 Query: 181 LRELLGGPQAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSG 240 LRELLGGPQAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSG Sbjct: 185 LRELLGGPQAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSG 244 Query: 241 DLAGELEELEEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYAS 300 DLAGELEELEEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYAS Sbjct: 245 DLAGELEELEEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYAS 304 Query: 301 SVFRKAGVPEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTV 360 SVFRKAGVPEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTV Sbjct: 305 SVFRKAGVPEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTV 364 Query: 361 ALCLQSSFPWTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWI 420 ALCLQSSFPWTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWI Sbjct: 365 ALCLQSSFPWTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWI 424 Query: 421 MLILVGLGFPFIMEALSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLNFP 480 MLILVGLGFPFIMEALSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLNFP Sbjct: 425 MLILVGLGFPFIMEALSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLNFP 484 Query: 481 RRAQGPTWRSLEVIQSTEL 499 RRAQGPTWRSLEVIQSTEL Sbjct: 485 RRAQGPTWRSLEVIQSTEL 503 >gi|47933389 solute carrier family 2, member 9 protein isoform 2 [Homo sapiens] Length = 511 Score = 389 bits (1000), Expect = e-108 Identities = 195/463 (42%), Positives = 289/463 (62%) Query: 16 LLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDHLVLLMWSLIVS 75 LL+ A G +F +GYNLS++NAPT +I+ F NE+W+ R G P+ + L+WS+ VS Sbjct: 27 LLVASLAGAFGSSFLYGYNLSVVNAPTPYIKAFYNESWERRHGRPIDPDTLTLLWSVTVS 86 Query: 76 LYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGRLLVG 135 ++ +GGL G L+ + LGRK +LL NN F +SAA+L S +AG+FEM+++GR ++G Sbjct: 87 IFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIMG 146 Query: 136 VNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQAWPLLL 195 ++ GV++++ PMYL E +PKE+RG++ +AIF +G+ GQ++GL ELLG WP L Sbjct: 147 IDGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTWPYLF 206 Query: 196 ASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGELEELEEERAA 255 +VP +QL SLP LP+SPRYLL++ + + A + G D++ E+EE+ E Sbjct: 207 GVIVVPAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFLGKADVSQEVEEVLAESRV 266 Query: 256 CQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGVPEAKIQY 315 + R EL + +R QV +++V + +LCG ++++ Y +S+F KAG+P AKI Y Sbjct: 267 QRSIRLVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGIPPAKIPY 326 Query: 316 AIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVALCLQSSFPWTLYLA 375 + TG E L AV S +VIE +GRR LLIGG+ LM + T+ L LQ PW YL+ Sbjct: 327 VTLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLTITLTLQDHAPWVPYLS 386 Query: 376 MACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGLGFPFIMEA 435 + I A I SF GP G+ IL E F Q RPAA ++ G + W+ VGL FPFI ++ Sbjct: 387 IVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAVGLLFPFIQKS 446 Query: 436 LSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLN 478 L + ++ F +C+ GAIY LPETK +T+ EIS+ + N Sbjct: 447 LDTYCFLVFATICITGAIYLYFVLPETKNRTYAEISQAFSKRN 489 >gi|47933387 solute carrier family 2, member 9 protein isoform 1 [Homo sapiens] Length = 540 Score = 389 bits (1000), Expect = e-108 Identities = 195/463 (42%), Positives = 289/463 (62%) Query: 16 LLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDHLVLLMWSLIVS 75 LL+ A G +F +GYNLS++NAPT +I+ F NE+W+ R G P+ + L+WS+ VS Sbjct: 56 LLVASLAGAFGSSFLYGYNLSVVNAPTPYIKAFYNESWERRHGRPIDPDTLTLLWSVTVS 115 Query: 76 LYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGRLLVG 135 ++ +GGL G L+ + LGRK +LL NN F +SAA+L S +AG+FEM+++GR ++G Sbjct: 116 IFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIMG 175 Query: 136 VNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQAWPLLL 195 ++ GV++++ PMYL E +PKE+RG++ +AIF +G+ GQ++GL ELLG WP L Sbjct: 176 IDGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTWPYLF 235 Query: 196 ASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGELEELEEERAA 255 +VP +QL SLP LP+SPRYLL++ + + A + G D++ E+EE+ E Sbjct: 236 GVIVVPAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFLGKADVSQEVEEVLAESRV 295 Query: 256 CQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGVPEAKIQY 315 + R EL + +R QV +++V + +LCG ++++ Y +S+F KAG+P AKI Y Sbjct: 296 QRSIRLVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGIPPAKIPY 355 Query: 316 AIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVALCLQSSFPWTLYLA 375 + TG E L AV S +VIE +GRR LLIGG+ LM + T+ L LQ PW YL+ Sbjct: 356 VTLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLTITLTLQDHAPWVPYLS 415 Query: 376 MACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGLGFPFIMEA 435 + I A I SF GP G+ IL E F Q RPAA ++ G + W+ VGL FPFI ++ Sbjct: 416 IVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAVGLLFPFIQKS 475 Query: 436 LSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLN 478 L + ++ F +C+ GAIY LPETK +T+ EIS+ + N Sbjct: 476 LDTYCFLVFATICITGAIYLYFVLPETKNRTYAEISQAFSKRN 518 >gi|4507013 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 isoform 1 [Homo sapiens] Length = 501 Score = 389 bits (999), Expect = e-108 Identities = 202/472 (42%), Positives = 295/472 (62%), Gaps = 3/472 (0%) Query: 10 MIQGRILLLTICA---AGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDHLV 66 M +GR+ L+ A A G +FQ+GYN++ +N+P L +Q+F NET+ RTGE + D + Sbjct: 8 MKEGRLTLVLALATLIAAFGSSFQYGYNVAAVNSPALLMQQFYNETYYGRTGEFMEDFPL 67 Query: 67 LLMWSLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEM 126 L+WS+ VS++P GG G+LL GPL GRK +LL NNIF + AIL G SR A SFE+ Sbjct: 68 TLLWSVTVSMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRVATSFEL 127 Query: 127 IMLGRLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLG 186 I++ RLLVG+ AGVS N+ PMYLGE APK LRGA+ + +F +GI++ Q+ GLR LL Sbjct: 128 IIISRLLVGICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIFGLRNLLA 187 Query: 187 GPQAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGEL 246 WP+LL VP ALQL LP PESPRYLLI D A AL+ LRG + E+ Sbjct: 188 NVDGWPILLGLTGVPAALQLLLLPFFPESPRYLLIQKKDEAAAKKALQTLRGWDSVDREV 247 Query: 247 EELEEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKA 306 E+ +E A + +LF+ R+LR Q+ S++VL +L G +++Y YA ++ A Sbjct: 248 AEIRQEDEAEKAAGFISVLKLFRMRSLRWQLLSIIVLMGGQQLSGVNAIYYYADQIYLSA 307 Query: 307 GVPEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVALCLQS 366 GVPE +QY GTG+ ++ + V+E +GRR+LL+ G+S+ + T AL LQ Sbjct: 308 GVPEEHVQYVTAGTGAVNVVMTFCAVFVVELLGRRLLLLLGFSICLIACCVLTAALALQD 367 Query: 367 SFPWTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVG 426 + W Y+++ C+ ++++ +GP+ + +L TE+F Q +RP+A MV G++ W+ VG Sbjct: 368 TVSWMPYISIVCVISYVIGHALGPSPIPALLITEIFLQSSRPSAFMVGGSVHWLSNFTVG 427 Query: 427 LGFPFIMEALSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLN 478 L FPFI E L + ++ F +C+ IY L +PETK KTF EI++ ++N Sbjct: 428 LIFPFIQEGLGPYSFIVFAVICLLTTIYIFLIVPETKAKTFIEINQIFTKMN 479 >gi|134053883 intestinal facilitative glucose transporter 7 [Homo sapiens] Length = 512 Score = 374 bits (959), Expect = e-103 Identities = 199/472 (42%), Positives = 287/472 (60%), Gaps = 1/472 (0%) Query: 7 RSRMIQGRILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDHLV 66 R +Q +LL T+ AA G FQ+GYNLS++N P + F NET+ R + L+ Sbjct: 15 REGRLQPTLLLATLSAA-FGSAFQYGYNLSVVNTPHKVFKSFYNETYFERHATFMDGKLM 73 Query: 67 LLMWSLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEM 126 LL+WS VS++PLGGL G+LL G L + GRK +LL+NNIF + AIL G S+ A +FE+ Sbjct: 74 LLLWSCTVSMFPLGGLLGSLLVGLLVDSCGRKGTLLINNIFAIIPAILMGVSKVAKAFEL 133 Query: 127 IMLGRLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLG 186 I+ R+++GV AG+S + PMYLGE APK LRG V + +F +G+ + Q+ L+ +LG Sbjct: 134 IVFSRVVLGVCAGISYSALPMYLGELAPKNLRGMVGTMTEVFVIVGVFLAQIFSLQAILG 193 Query: 187 GPQAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGEL 246 P WP+LLA VP LQL +LP PESPRY LI GD ALRRLRG D+ EL Sbjct: 194 NPAGWPVLLALTGVPALLQLLTLPFFPESPRYSLIQKGDEATARQALRRLRGHTDMEAEL 253 Query: 247 EELEEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKA 306 E++ E A + L R+LR Q+ S++VL + +L G +++ YA +++ A Sbjct: 254 EDMRAEARAERAEGHLSVLHLCALRSLRWQLLSIIVLMAGQQLSGINAINYYADTIYTSA 313 Query: 307 GVPEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVALCLQS 366 GV A QY +G+G ++ + S V++ER+GRR LL+ GY + + TV L Q+ Sbjct: 314 GVEAAHSQYVTVGSGVVNIVMTITSAVLVERLGRRHLLLAGYGICGSACLVLTVVLLFQN 373 Query: 367 SFPWTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVG 426 P YL + C+FA+I IGP+ V ++ TE+F Q +R AA MV GA+ W+ ++G Sbjct: 374 RVPELSYLGIICVFAYIAGHSIGPSPVPSVVRTEIFLQSSRRAAFMVDGAVHWLTNFIIG 433 Query: 427 LGFPFIMEALSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLN 478 FP I EA+ + ++ F G+C+ AIY + +PETKGKTF EI++ + N Sbjct: 434 FLFPSIQEAIGAYSFIIFAGICLLTAIYIYVVIPETKGKTFVEINRIFAKRN 485 >gi|166795299 solute carrier family 2 (facilitated glucose transporter), member 1 [Homo sapiens] Length = 492 Score = 320 bits (819), Expect = 2e-87 Identities = 171/464 (36%), Positives = 264/464 (56%), Gaps = 4/464 (0%) Query: 8 SRMIQGRILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDHLVL 67 S+ + GR++L + G+ QFGYN +INAP I+EF N+TW R GE + + Sbjct: 5 SKKLTGRLMLAV--GGAVLGSLQFGYNTGVINAPQKVIEEFYNQTWVHRYGESILPTTLT 62 Query: 68 LMWSLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMI 127 +WSL V+++ +GG+ G+ G GR+ S+L+ N+ +A+L GFS+ SFEM+ Sbjct: 63 TLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFEML 122 Query: 128 MLGRLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGG 187 +LGR ++GV G++ PMY+GE +P LRGA+ + +GI++ QV GL ++G Sbjct: 123 ILGRFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIMGN 182 Query: 188 PQAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGELE 247 WPLLL+ +P LQ LP PESPR+LLI+ + + L++LRG+ D+ +L+ Sbjct: 183 KDLWPLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTHDLQ 242 Query: 248 ELEEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAG 307 E++EE + ELF+ A R+ + VVL + +L G ++V+ Y++S+F KAG Sbjct: 243 EMKEESRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEKAG 302 Query: 308 VPEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVALCLQSS 367 V + YA IG+G VVS V+ER GRR L + G + M + T+AL L Sbjct: 303 VQQP--VYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILMTIALALLEQ 360 Query: 368 FPWTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGL 427 PW YL++ IF F+ F +GP + + ELF Q RPAA V G W +VG+ Sbjct: 361 LPWMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGM 420 Query: 428 GFPFIMEALSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEIS 471 F ++ + ++++ F + V I+T +PETKG+TF EI+ Sbjct: 421 CFQYVEQLCGPYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEIA 464 >gi|4507011 glucose transporter 4 [Homo sapiens] Length = 509 Score = 312 bits (800), Expect = 4e-85 Identities = 180/488 (36%), Positives = 276/488 (56%), Gaps = 15/488 (3%) Query: 16 LLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTG----EPLPDHLVLLMWS 71 L+L + +A +G + QFGYN+ +INAP I++ NETW R G +P + +W+ Sbjct: 24 LVLAVFSAVLG-SLQFGYNIGVINAPQKVIEQSYNETWLGRQGPEGPSSIPPGTLTTLWA 82 Query: 72 LIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGR 131 L V+++ +GG+ + L G ++ LGRK+++LVNN+ V L G + A S+EM++LGR Sbjct: 83 LSVAIFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGSLMGLANAAASYEMLILGR 142 Query: 132 LLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQAW 191 L+G +G++ + PMY+GE AP LRGA+ + + +GI++ QV+GL LLG W Sbjct: 143 FLIGAYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAIVIGILIAQVLGLESLLGTASLW 202 Query: 192 PLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGELEELEE 251 PLLL ++P LQL LP PESPRYL I +L+RL G D++G L EL++ Sbjct: 203 PLLLGLTVLPALLQLVLLPFCPESPRYLYIIQNLEGPARKSLKRLTGWADVSGVLAELKD 262 Query: 252 ERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGVPEA 311 E+ + R +L R R+ + VVL + +L G ++V+ Y++S+F AGV + Sbjct: 263 EKRKLERERPLSLLQLLGSRTHRQPLIIAVVLQLSQQLSGINAVFYYSTSIFETAGVGQP 322 Query: 312 KIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVALCLQSSFPWT 371 YA IG G + +VS +++ER GRR L + G + M + TVAL L P Sbjct: 323 --AYATIGAGVVNTVFTLVSVLLVERAGRRTLHLLGLAGMCGCAILMTVALLLLERVPAM 380 Query: 372 LYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGLGFPF 431 Y+++ IF F+ F IGP + + ELF Q RPAA V G W ++G+GF + Sbjct: 381 SYVSIVAIFGFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGFSNWTSNFIIGMGFQY 440 Query: 432 IMEALSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLNFPRRAQGPTWRSL 491 + EA+ ++++ F + + I+T L +PET+G+TF +IS HR P+ Sbjct: 441 VAEAMGPYVFLLFAVLLLGFFIFTFLRVPETRGRTFDQISAAFHRT--------PSLLEQ 492 Query: 492 EVIQSTEL 499 EV STEL Sbjct: 493 EVKPSTEL 500 >gi|5902090 solute carrier family 2 (facilitated glucose transporter), member 3 [Homo sapiens] Length = 496 Score = 292 bits (747), Expect = 6e-79 Identities = 161/457 (35%), Positives = 258/457 (56%), Gaps = 3/457 (0%) Query: 16 LLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDHLVLLMWSLIVS 75 L+ I A IG +FQFGYN +INAP I+EF N+T + P + L+ +WSL V+ Sbjct: 10 LIFAITVATIG-SFQFGYNTGVINAPEKIIKEFINKTLTDKGNAPPSEVLLTSLWSLSVA 68 Query: 76 LYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGRLLVG 135 ++ +GG+ G+ G GR+ S+L+ N+ V+ G + A S EM++LGRL++G Sbjct: 69 IFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGRLVIG 128 Query: 136 VNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQAWPLLL 195 + G+ PMY+GE +P LRGA + + +GI++ Q+ GL +LG + WPLLL Sbjct: 129 LFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEELWPLLL 188 Query: 196 ASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGELEELEEERAA 255 ++P LQ A+LP PESPR+LLI+ + E L+RL G+ D++ +++E+++E A Sbjct: 189 GFTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRLWGTQDVSQDIQEMKDESAR 248 Query: 256 CQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGVPEAKIQY 315 + ELF+ + R+ + +VL + +L G ++V+ Y++ +F+ AGV E Y Sbjct: 249 MSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQEP--IY 306 Query: 316 AIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVALCLQSSFPWTLYLA 375 A IG G + VVS ++ER GRR L + G M ++ TV+L L+ ++ ++ Sbjct: 307 ATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKDNYNGMSFVC 366 Query: 376 MACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGLGFPFIMEA 435 + I F+ F IGP + + ELF Q RPAA V G W LVGL FP Sbjct: 367 IGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAHY 426 Query: 436 LSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISK 472 L ++++ F G + +T +PET+G+TF++I++ Sbjct: 427 LGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITR 463 >gi|23592238 glucose transporter 14 [Homo sapiens] Length = 520 Score = 284 bits (726), Expect = 1e-76 Identities = 156/457 (34%), Positives = 256/457 (56%), Gaps = 3/457 (0%) Query: 16 LLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDHLVLLMWSLIVS 75 L+ I A IG +FQFGYN +INAP I+EF N+T + P + L+ +WSL V+ Sbjct: 34 LIFAITVATIG-SFQFGYNTGVINAPETIIKEFINKTLTDKANAPPSEVLLTNLWSLSVA 92 Query: 76 LYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGRLLVG 135 ++ +GG+ G+ G GR+ S+L+ N+ + L G + A S EM++LGRL++G Sbjct: 93 IFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMGLCKIAESVEMLILGRLVIG 152 Query: 136 VNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQAWPLLL 195 + G+ PMY+GE +P LRGA + + +GI++ Q+ GL +LG + WP+LL Sbjct: 153 LFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIFGLELILGSEELWPVLL 212 Query: 196 ASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGELEELEEERAA 255 ++P LQ A+LP PESPR+LLI+ E L+RL G+ D++ +++E+++E A Sbjct: 213 GFTILPAILQSAALPCCPESPRFLLINRKKEENATRILQRLWGTQDVSQDIQEMKDESAR 272 Query: 256 CQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGVPEAKIQY 315 + ELF+ + R+ + +VL + +L G ++V+ Y++ +F+ AGV + Y Sbjct: 273 MSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQQP--IY 330 Query: 316 AIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVALCLQSSFPWTLYLA 375 A I G + ++S ++ER GRR L + G M ++ TV+L L++ + ++ Sbjct: 331 ATISAGVVNTIFTLLSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKNHYNGMSFVC 390 Query: 376 MACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGLGFPFIMEA 435 + I F+ F IGP + + ELF Q RPAA V G W LVGL FP Sbjct: 391 IGAILVFVACFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAYY 450 Query: 436 LSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISK 472 L ++++ F G + +T +PET+G+TF++I++ Sbjct: 451 LGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITR 487 >gi|4557851 solute carrier family 2 (facilitated glucose transporter), member 2 [Homo sapiens] Length = 524 Score = 253 bits (647), Expect = 2e-67 Identities = 157/499 (31%), Positives = 249/499 (49%), Gaps = 45/499 (9%) Query: 16 LLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDH----------- 64 L+ T+ A +G +FQFGY++ +INAP Q+ ++ G PL D Sbjct: 10 LVFTVITAVLG-SFQFGYDIGVINAP----QQVIISHYRHVLGVPLDDRKAINNYVINST 64 Query: 65 ---------------------------LVLLMWSLIVSLYPLGGLFGALLAGPLAITLGR 97 L+ ++WSL VS + +GG+ + G L TLGR Sbjct: 65 DELPTISYSMNPKPTPWAEEETVAAAQLITMLWSLSVSSFAVGGMTASFFGGWLGDTLGR 124 Query: 98 KKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGRLLVGVNAGVSMNIQPMYLGESAPKEL 157 K++LV NI + A+L GFS+ S +I+ GR + G+ G+ + PMY+GE AP L Sbjct: 125 IKAMLVANILSLVGALLMGFSKLGPSHILIIAGRSISGLYCGLISGLVPMYIGEIAPTAL 184 Query: 158 RGAVAMSSAIFTALGIVMGQVVGLRELLGGPQAWPLLLASCLVPGALQLASLPLLPESPR 217 RGA+ + GI++ Q++GL +LG W +LL V LQ L PESPR Sbjct: 185 RGALGTFHQLAIVTGILISQIIGLEFILGNYDLWHILLGLSGVRAILQSLLLFFCPESPR 244 Query: 218 YLLIDCGDTEACLAALRRLRGSGDLAGELEELEEERAACQGCRARRPWELFQHRALRRQV 277 YL I + +L+RLRG D+ ++ E+ +ER + +LF + + R+ + Sbjct: 245 YLYIKLDEEVKAKQSLKRLRGYDDVTKDINEMRKEREEASSEQKVSIIQLFTNSSYRQPI 304 Query: 278 TSLVVLGSAMELCGNDSVYAYASSVFRKAGVPEAKIQYAIIGTGSCELLTAVVSCVVIER 337 ++L A + G + ++ Y++S+F+ AG+ +K YA IG G+ ++ VS ++E+ Sbjct: 305 LVALMLHVAQQFSGINGIFYYSTSIFQTAGI--SKPVYATIGVGAVNMVFTAVSVFLVEK 362 Query: 338 VGRRVLLIGGYSLMTCWGSIFTVALCLQSSFPWTLYLAMACIFAFILSFGIGPAGVTGIL 397 GRR L + G S M +V L L + F W Y++M IF F+ F IGP + + Sbjct: 363 AGRRSLFLIGMSGMFVCAIFMSVGLVLLNKFSWMSYVSMIAIFLFVSFFEIGPGPIPWFM 422 Query: 398 ATELFDQMARPAACMVCGALMWIMLILVGLGFPFIMEALSHFLYVPFLGVCVCGAIYTGL 457 E F Q RPAA + W +V L F +I + +++ F GV + ++T Sbjct: 423 VAEFFSQGPRPAALAIAAFSNWTCNFIVALCFQYIADFCGPYVFFLFAGVLLAFTLFTFF 482 Query: 458 FLPETKGKTFQEISKELHR 476 +PETKGK+F+EI+ E + Sbjct: 483 KVPETKGKSFEEIAAEFQK 501 >gi|207447703 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 isoform 2 [Homo sapiens] Length = 244 Score = 179 bits (454), Expect = 5e-45 Identities = 91/179 (50%), Positives = 124/179 (69%), Gaps = 3/179 (1%) Query: 10 MIQGRILLLTICA---AGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDHLV 66 M +GR+ L+ A A G +FQ+GYN++ +N+P L +Q+F NET+ RTGE + D + Sbjct: 8 MKEGRLTLVLALATLIAAFGSSFQYGYNVAAVNSPALLMQQFYNETYYGRTGEFMEDFPL 67 Query: 67 LLMWSLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEM 126 L+WS+ VS++P GG G+LL GPL GRK +LL NNIF + AIL G SR A SFE+ Sbjct: 68 TLLWSVTVSMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRVATSFEL 127 Query: 127 IMLGRLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELL 185 I++ RLLVG+ AGVS N+ PMYLGE APK LRGA+ + +F +GI++ Q+ GLR LL Sbjct: 128 IIISRLLVGICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIFGLRNLL 186 >gi|21361449 solute carrier family 2 (facilitated glucose transporter), member 8 [Homo sapiens] Length = 477 Score = 125 bits (313), Expect = 1e-28 Identities = 129/491 (26%), Positives = 213/491 (43%), Gaps = 72/491 (14%) Query: 12 QGRILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLP--DHLVLLM 69 +GR + L AA +G FG+ L + +Q R P P D Sbjct: 22 RGRRVFLAAFAAALG-PLSFGFALGYSSPAIPSLQ---------RAAPPAPRLDDAAASW 71 Query: 70 WSLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNI-FVVSAAILFGFSRKAGSFEMIM 128 + +V+L G G +L G L GRK SLL+ ++ FV A++ A M++ Sbjct: 72 FGAVVTL---GAAAGGVLGGWLVDRAGRKLSLLLCSVPFVAGFAVITA----AQDVWMLL 124 Query: 129 LGRLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGP 188 GRLL G+ GV+ + P+Y+ E A +RG + + +GI+ L L G Sbjct: 125 GGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVVGIL------LAYLAGWV 178 Query: 189 QAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGELEE 248 W L VP +L L + +PE+PR+LL EA +AALR L GS + E Sbjct: 179 LEWRWLAVLGCVPPSLMLLLMCFMPETPRFLLTQHRRQEA-MAALRFLWGS-EQGWEDPP 236 Query: 249 LEEERAACQGCRARRPWELFQHRALRRQ--VTSLVVLGSAM----ELCGNDSVYAYASSV 302 + E++ H AL RQ + ++G ++ +L G ++V YA ++ Sbjct: 237 IGAEQSF--------------HLALLRQPGIYKPFIIGVSLMAFQQLSGVNAVMFYAETI 282 Query: 303 FRKAGVPEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVAL 362 F +A ++ + ++G ++L V+ ++++R GRR+LL+ +M S F Sbjct: 283 FEEAKFKDSSLASVVVGV--IQVLFTAVAALIMDRAGRRLLLVLSGVVMVFSTSAFGAYF 340 Query: 363 CLQSSFPWT---------------------LYLAMACIFAFILSFGIGPAGVTGILATEL 401 L P +LA+ + FI F +G + +L +E+ Sbjct: 341 KLTQGGPGNSSHVAISAPVSAQPVDASVGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEI 400 Query: 402 FDQMARPAACMVCGALMWIMLILVGLGFPFIMEALSHF-LYVPFLGVCVCGAIYTGLFLP 460 F + A +C W+M LV F +ME L + + C+ ++T +P Sbjct: 401 FPLHVKGVATGICVLTNWLMAFLVTKEFSSLMEVLRPYGAFWLASAFCIFSVLFTLFCVP 460 Query: 461 ETKGKTFQEIS 471 ETKGKT ++I+ Sbjct: 461 ETKGKTLEQIT 471 >gi|223029432 solute carrier family 2 (facilitated glucose transporter), member 6 isoform 1 [Homo sapiens] Length = 507 Score = 123 bits (308), Expect = 4e-28 Identities = 128/492 (26%), Positives = 215/492 (43%), Gaps = 69/492 (14%) Query: 14 RILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPD-HLVLLMWSL 72 R+ L T A + G F FGY L + +P + E + + PD HL S Sbjct: 37 RVFLATFAA--VLGNFSFGYAL-VYTSPVIPALERSLD----------PDLHLTKSQASW 83 Query: 73 IVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFE--MIMLG 130 S++ LG G L A L LGRK S++ + V SAA G++ AG+ M++LG Sbjct: 84 FGSVFTLGAAAGGLSAMILNDLLGRKLSIMFSA--VPSAA---GYALMAGAHGLWMLLLG 138 Query: 131 RLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQA 190 R L G G++ P+Y+ E AP +RGA+ + + G + +GL LL Sbjct: 139 RTLTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGL--LL----P 192 Query: 191 WPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSG-DLAGELEEL 249 W L + P + + L +P SPR+LL D EA L AL LRG+ D+ E E++ Sbjct: 193 WRWLAVAGEAPVLIMILLLSFMPNSPRFLLSRGRDEEA-LRALAWLRGTDVDVHWEFEQI 251 Query: 250 EEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGVP 309 ++ + +R W + + R +T +++ +L G + Y S+F V Sbjct: 252 QDN---VRRQSSRVSWAEARAPHVCRPITVALLMRLLQQLTGITPILVYLQSIFDSTAVL 308 Query: 310 EAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLM------------------ 351 A I G+ LL+ +++ + ++ GR+VLL ++M Sbjct: 309 LPPKDDAAI-VGAVRLLSVLIAALTMDLAGRKVLLFVSAAIMFAANLTLGLYIHFGPRPL 367 Query: 352 ----------TCWGSIFTVALCLQSSFPWTLYLAMACIFAFILSFGIGPAGVTGILATEL 401 WG + A L + + + + FI+ + +G +T +L +E+ Sbjct: 368 SPNSTAGLESESWGDL---AQPLAAPAGYLTLVPLLATMLFIMGYAVGWGPITWLLMSEV 424 Query: 402 FDQMARPAACMVCGALMWIMLILVGLGFPFIMEALSHFLYVPFL---GVCVCGAIYTGLF 458 AR A +C W+ ++ F ++ L VPF +C+ ++TG Sbjct: 425 LPLRARGVASGLCVLASWLTAFVLTKSFLPVVSTFG--LQVPFFFFAAICLVSLVFTGCC 482 Query: 459 LPETKGKTFQEI 470 +PETKG++ ++I Sbjct: 483 VPETKGRSLEQI 494 >gi|223029430 solute carrier family 2 (facilitated glucose transporter), member 6 isoform 2 [Homo sapiens] Length = 445 Score = 117 bits (292), Expect = 3e-26 Identities = 122/464 (26%), Positives = 202/464 (43%), Gaps = 75/464 (16%) Query: 14 RILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPD-HLVLLMWSL 72 R+ L T A + G F FGY L + +P + E + + PD HL S Sbjct: 37 RVFLATFAA--VLGNFSFGYAL-VYTSPVIPALERSLD----------PDLHLTKSQASW 83 Query: 73 IVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFE--MIMLG 130 S++ LG G L A L LGRK S++ + V SAA G++ AG+ M++LG Sbjct: 84 FGSVFTLGAAAGGLSAMILNDLLGRKLSIMFSA--VPSAA---GYALMAGAHGLWMLLLG 138 Query: 131 RLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQA 190 R L G G++ P+Y+ E AP +RGA+ + + G + +GL LL Sbjct: 139 RTLTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGL--LL----P 192 Query: 191 WPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSG-DLAGELEEL 249 W L + P + + L +P SPR+LL D EA L AL LRG+ D+ E E++ Sbjct: 193 WRWLAVAGEAPVLIMILLLSFMPNSPRFLLSRGRDEEA-LRALAWLRGTDVDVHWEFEQI 251 Query: 250 EEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGVP 309 ++ + +R W + + R +T +++ +L G + Y S+F V Sbjct: 252 QDN---VRRQSSRVSWAEARAPHVCRPITVALLMRLLQQLTGITPILVYLQSIFDSTAVL 308 Query: 310 EAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVALCLQSSFP 369 A I G+ LL+ +++ + ++ GR+VLL Sbjct: 309 LPPKDDAAI-VGAVRLLSVLIAALTMDLAGRKVLL------------------------- 342 Query: 370 WTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGLGF 429 F+ + +G +T +L +E+ AR A +C W+ ++ F Sbjct: 343 ------------FVSGYAVGWGPITWLLMSEVLPLRARGVASGLCVLASWLTAFVLTKSF 390 Query: 430 PFIMEALSHFLYVPFL---GVCVCGAIYTGLFLPETKGKTFQEI 470 ++ L VPF +C+ ++TG +PETKG++ ++I Sbjct: 391 LPVVSTFG--LQVPFFFFAAICLVSLVFTGCCVPETKGRSLEQI 432 >gi|203098995 solute carrier family 2 (facilitated glucose transporter), member 13 [Homo sapiens] Length = 648 Score = 93.2 bits (230), Expect = 5e-19 Identities = 80/325 (24%), Positives = 140/325 (43%), Gaps = 24/325 (7%) Query: 27 GTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDHLVLLMWSLIVSLYPLGGLFGAL 86 G F FGY+ +++ L ++ + L L L+VS AL Sbjct: 91 GGFLFGYDTGVVSGAMLLLKRQLS--------------LDALWQELLVSSTVGAAAVSAL 136 Query: 87 LAGPLAITLGRKKS-LLVNNIFVVSAAILFGFSRKAGSFEMIMLGRLLVGVNAGVSMNIQ 145 G L GR+ + LL + +F +A+L + K E ++ GRL+VG+ G++ Sbjct: 137 AGGALNGVFGRRAAILLASALFTAGSAVLAAANNK----ETLLAGRLVVGLGIGIASMTV 192 Query: 146 PMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQAWPLLLASCLVPGALQ 205 P+Y+ E +P LRG + + +F G VV W +L VP +Q Sbjct: 193 PVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKDGWRYMLGLAAVPAVIQ 252 Query: 206 LASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGELEELE---EERAACQGCRAR 262 LPESPR+ LI G T+ L ++RG+ + E + ++ EE G Sbjct: 253 FFGFLFLPESPRW-LIQKGQTQKARRILSQMRGNQTIDEEYDSIKNNIEEEEKEVGSAGP 311 Query: 263 RPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGVPEAKIQYAIIG-TG 321 + + RR + L +L G +++ Y++++ + +GV + ++ + T Sbjct: 312 VICRMLSYPPTRRALIVGCGLQMFQQLSGINTIMYYSATILQMSGVEDDRLAIWLASVTA 371 Query: 322 SCELLTAVVSCVVIERVGRRVLLIG 346 + +V ++E+VGRR L G Sbjct: 372 FTNFIFTLVGVWLVEKVGRRKLTFG 396 Score = 43.9 bits (102), Expect = 3e-04 Identities = 30/104 (28%), Positives = 47/104 (45%), Gaps = 4/104 (3%) Query: 368 FPWTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGL 427 + WT L + F G+GP T + +E++ AR + WI +LV L Sbjct: 505 YSWTALLGLILYLVFFAP-GMGPMPWT--VNSEIYPLWARSTGNACSSGINWIFNVLVSL 561 Query: 428 GFPFIMEALSHF-LYVPFLGVCVCGAIYTGLFLPETKGKTFQEI 470 F E L+++ + + G G ++ LPETKGK +EI Sbjct: 562 TFLHTAEYLTYYGAFFLYAGFAAVGLLFIYGCLPETKGKKLEEI 605 >gi|21553331 solute carrier family 2 (facilitated glucose transporter), member 12 [Homo sapiens] Length = 617 Score = 87.0 bits (214), Expect = 4e-17 Identities = 75/341 (21%), Positives = 152/341 (44%), Gaps = 25/341 (7%) Query: 13 GRILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDHLVLLMWSL 72 G L+ A + G GY L II+ L I+ + + + Sbjct: 37 GMFTFLSSVTAAVSGLL-VGYELGIISGALLQIKTLLALSCHEQ--------------EM 81 Query: 73 IVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGRL 132 +VS +G L +L G L GR+ ++++++ + +++ S S+ ++++GR+ Sbjct: 82 VVSSLVIGALLASLTGGVLIDRYGRRTAIILSSCLLGLGSLVLILSL---SYTVLIVGRI 138 Query: 133 LVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQAWP 192 +GV+ +S +Y+ E AP+ RG + + + +GI+ + W Sbjct: 139 AIGVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMIVIGILSAYISNY-AFANVFHGWK 197 Query: 193 LLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGELEELEEE 252 + + G LQ ++ LP SPR+L++ G A L RLR D EEL Sbjct: 198 YMFGLVIPLGVLQAIAMYFLPPSPRFLVMK-GQEGAASKVLGRLRALSDTT---EELTVI 253 Query: 253 RAACQGCRARRPWELFQHR-ALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGVPEA 311 +++ + W+LF+ + +R ++ + L +++ G ++ YAS+V + G Sbjct: 254 KSSLKDEYQYSFWDLFRSKDNMRTRIMIGLTLVFFVQITGQPNILFYASTVLKSVGFQSN 313 Query: 312 K-IQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLM 351 + A G G ++++ + + ++++ VG + L G S+M Sbjct: 314 EAASLASTGVGVVKVISTIPATLLVDHVGSKTFLCIGSSVM 354 Score = 48.1 bits (113), Expect = 2e-05 Identities = 26/111 (23%), Positives = 60/111 (54%), Gaps = 7/111 (6%) Query: 373 YLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGLGFPFI 432 +L++A + ++ +F IG + ++ +E+F R A + ++ W + +L+ L F + Sbjct: 462 WLSLASLLVYVAAFSIGLGPMPWLVLSEIFPGGIRGRAMALTSSMNWGINLLISLTFLTV 521 Query: 433 MEALSH----FLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLNF 479 + + F+Y + + ++ +F+PETKG + ++IS EL ++N+ Sbjct: 522 TDLIGLPWVCFIYTI---MSLASLLFVVMFIPETKGCSLEQISMELAKVNY 569 >gi|13540547 solute carrier family 2 member 10 [Homo sapiens] Length = 541 Score = 84.3 bits (207), Expect = 2e-16 Identities = 90/339 (26%), Positives = 145/339 (42%), Gaps = 42/339 (12%) Query: 17 LLTICAA-GIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDHLVLLMWSLIVS 75 +L +CA+ + G FGY L++I+ L +Q L L L +V Sbjct: 7 VLPLCASVSLLGGLTFGYELAVISGALLPLQ--------------LDFGLSCLEQEFLVG 52 Query: 76 LYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGRLLVG 135 LG L +L+ G L GRK+++L +N+ +++ ++ G AGS ++LGR +VG Sbjct: 53 SLLLGALLASLVGGFLIDCYGRKQAILGSNLVLLAGSLTLGL---AGSLAWLVLGRAVVG 109 Query: 136 VNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQAWPLLL 195 +S +Y+ E RG + +GI++ + L G P W + Sbjct: 110 FAISLSSMACCIYVSELVGPRQRGVLVSLYEAGITVGILLSYALNYA-LAGTPWGWRHMF 168 Query: 196 ASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGELEELEEERAA 255 P LQ SL LP D A L L+G GE +L R Sbjct: 169 GWATAPAVLQSLSLLFLPAGT--------DETATHKDLIPLQG-----GEAPKLGPGRPR 215 Query: 256 CQGCRARRPWELFQHRALRRQVTSLVVLGSAM--ELCGNDSVYAYASSVFRKAGVPE-AK 312 +LF+ R R T+ V LG + +L G +V YAS++F G + Sbjct: 216 YSFL------DLFRARDNMRGRTT-VGLGLVLFQQLTGQPNVLCYASTIFSSVGFHGGSS 268 Query: 313 IQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLM 351 A +G G+ ++ + + +++R GRR LL+ G +LM Sbjct: 269 AVLASVGLGAVKVAATLTAMGLVDRAGRRALLLAGCALM 307 Score = 51.6 bits (122), Expect = 2e-06 Identities = 32/113 (28%), Positives = 53/113 (46%), Gaps = 8/113 (7%) Query: 370 WTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGLGF 429 WT A+ C+ F+ +F G VT ++ +E++ R A C + W + + L F Sbjct: 410 WT---ALLCLMVFVSAFSFGFGPVTWLVLSEIYPVEIRGRAFAFCNSFNWAANLFISLSF 466 Query: 430 PFIMEALS---HFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLNF 479 ++ + FL V G IY LF+PETKG++ EI ++ + F Sbjct: 467 LDLIGTIGLSWTFLLYGLTAVLGLGFIY--LFVPETKGQSLAEIDQQFQKRRF 517 >gi|4506999 solute carrier family 22 member 1 isoform a [Homo sapiens] Length = 554 Score = 61.2 bits (147), Expect = 2e-09 Identities = 103/410 (25%), Positives = 167/410 (40%), Gaps = 32/410 (7%) Query: 72 LIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGR 131 L S G LFG+L G A GRK LL + + +L FS ++ ++L R Sbjct: 150 LFQSCLNAGFLFGSLGVGYFADRFGRKLCLLGTVLVNAVSGVLMAFS---PNYMSMLLFR 206 Query: 132 LLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQAW 191 LL G+ + + + E R VA+ + +G+V + GL L W Sbjct: 207 LLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIMYQMAFTVGLV--ALTGLAYAL---PHW 261 Query: 192 PLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDL-AGELEELE 250 L + +P L L +PESPR+LL +TEA + +G L +L+ L Sbjct: 262 RWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIKIMDHIAQKNGKLPPADLKMLS 321 Query: 251 EERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGVPE 310 E + +LF+ LR++ L M L DSV + G Sbjct: 322 LEEDVTEKLSPSFA-DLFRTPRLRKRTFIL------MYLWFTDSV--LYQGLILHMGATS 372 Query: 311 AKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVALCLQSSFPW 370 + + + E+ A ++ + I+RVG R+ + +L+ G+ V + + W Sbjct: 373 GNLYLDFLYSALVEIPGAFIALITIDRVG-RIYPMAMSNLLA--GAACLVMIFISPDLHW 429 Query: 371 TLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGLGFP 430 L + + C+ ++ I + ++ EL+ R MVC +L I G+ P Sbjct: 430 -LNIIIMCVGRMGITIAI---QMICLVNAELYPTFVRNLGVMVCSSLCDI----GGIITP 481 Query: 431 FIMEALSH-FLYVPFLGVCVCGAIYTG--LFLPETKGKTFQEISKELHRL 477 FI+ L + +P + V G + G L LPETKG E K+ L Sbjct: 482 FIVFRLREVWQALPLILFAVLGLLAAGVTLLLPETKGVALPETMKDAENL 531 >gi|170650643 solute carrier family 22, member 23 isoform a [Homo sapiens] Length = 686 Score = 56.2 bits (134), Expect = 7e-08 Identities = 99/431 (22%), Positives = 172/431 (39%), Gaps = 60/431 (13%) Query: 70 WSLIVSLYPL--GGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMI 127 W + ++ + L G +FG L+ G +A +GR+ LL + IF++ + S F + Sbjct: 227 WKVHIAKFSLLVGLIFGYLITGCIADWVGRRPVLLFSIIFILIFGLTVALSVNVTMFSTL 286 Query: 128 MLGRLLVG-VNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLG 186 R G AG+ + + + + E P R + M ++ G + + GL L Sbjct: 287 ---RFFEGFCLAGIILTLYALRI-ELCPPGKRFMITMVASFVAMAGQFL--MPGLAALC- 339 Query: 187 GPQAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAAL-----RRLRGSGD 241 + W +L A + P L L + PES R+L+ A L R+ GD Sbjct: 340 --RDWQVLQALIICPFLLMLLYWSIFPESLRWLMATQQFESAKRLILHFTQKNRMNPEGD 397 Query: 242 LAGELEELEEERAACQGCRARRPWELFQHRAL-RRQVTSLVVLGSAMELCGNDSVYAYAS 300 + G + ELE+E +RRP ++ + + R + +V+ L G + +A Sbjct: 398 IKGVIPELEKE-------LSRRPKKVCIVKVVGTRNLWKNIVVLCVNSLTGYGIHHCFAR 450 Query: 301 SVF-RKAGVPEAKIQYA-IIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIF 358 S+ + VP + YA T S L++ + CVV+ +GRR L+ + ++T S+ Sbjct: 451 SMMGHEVKVPLLENFYADYYTTASIALVSCLAMCVVVRFLGRRGGLL-LFMILTALASLL 509 Query: 359 TVALC-------------LQSSFPWTLYLAMACIFAFILSFGIGPAGVTGILATELFDQM 405 + L + S +A + + F S +G V E+ + Sbjct: 510 QLGLLNLIGKYSQHPDSGMSDSVKDKFSIAFSIVGMF-ASHAVGSLSV--FFCAEITPTV 566 Query: 406 ARPAACMVCGALMWIMLILVGLGFPFIMEAL-------SHFLYVPFLGVCVCGAIYTGLF 458 R CG L L+L GF + + +FL+ C I L Sbjct: 567 IR------CGGL---GLVLASAGFGMLTAPIIELHNQKGYFLHHIIFACCTLICIICILL 617 Query: 459 LPETKGKTFQE 469 LPE++ + E Sbjct: 618 LPESRDQNLPE 628 >gi|213021148 SVOP-like isoform 1 [Homo sapiens] Length = 492 Score = 55.5 bits (132), Expect = 1e-07 Identities = 46/167 (27%), Positives = 84/167 (50%), Gaps = 9/167 (5%) Query: 71 SLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLG 130 +L+ ++ G + ++L G LA GR K LL++ ++ ++L F A S+ + Sbjct: 87 ALVTTMVFFGYMVFSILFGLLADRYGRWKILLISFLWGAYFSLLTSF---APSYIWFVFL 143 Query: 131 RLLVGVNAGVSMNIQPMYLG-ESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQ 189 R +VG GVS + Q + + E P + RG + S +F G ++ ++GL ++ Sbjct: 144 RTMVG--CGVSGHSQGLIIKTEFLPTKYRGYMLPLSQVFWLAGSLL--IIGLASVIIPTI 199 Query: 190 AWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRL 236 W L+ +PG + + + +PES R+ + G+T A LA L R+ Sbjct: 200 GWRWLIRVASIPGIILIVAFKFIPESARF-NVSTGNTRAALATLERV 245 >gi|166064021 solute carrier family 22 (organic anion transporter), member 13 [Homo sapiens] Length = 551 Score = 54.3 bits (129), Expect = 3e-07 Identities = 101/422 (23%), Positives = 172/422 (40%), Gaps = 57/422 (13%) Query: 75 SLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGRLLV 134 S++ G L G L+ GPL +GRK ++L + + F SFE+ M R V Sbjct: 142 SVFMAGLLVGTLMFGPLCDRIGRKATILAQLLLFTLIGLATAF---VPSFELYMALRFAV 198 Query: 135 GVN-AGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQAWPL 193 AG+S + + P AV ++ F+ +GQ+V L L G + W L Sbjct: 199 ATAVAGLSFSNVTLLTEWVGPSWRTQAVVLAQCNFS-----LGQMV-LAGLAYGFRNWRL 252 Query: 194 LLASCLVPGALQLASLPLLPESPRYLLIDCGDTEAC-----LAALRRLRGSGDLAGELEE 248 L + PG L LPES R+LL EA A++ R + S +L + + Sbjct: 253 LQITGTAPGLLLFFYFWALPESARWLLTRGRMDEAIQLIQKAASVNRRKLSPEL---MNQ 309 Query: 249 LEEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGV 308 L E+ G +LF+H LR+ VT ++ + DS+ Y S+ + G Sbjct: 310 LVPEKTGPSG----NALDLFRHPQLRK-VTLIIFC-----VWFVDSLGYYGLSL--QVGD 357 Query: 309 PEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVALCLQSSF 368 + + G+ E+ S +++R GR+ +G + G + + + + + Sbjct: 358 FGLDVYLTQLIFGAVEVPARCSSIFMMQRFGRKWSQLG---TLVLGGLMCIIIIFIPADL 414 Query: 369 PWTLYL-----AMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLI 423 P + + MA AF +S+ + + ELF + R L+ I Sbjct: 415 PVVVTMLAVVGKMATAAAFTISY---------VYSAELFPTILRQTGM----GLVGIFSR 461 Query: 424 LVGLGFPFIMEALSHFLYVPFLGV----CVCGAIYTGLFLPETKGKTFQEISKELHRLNF 479 + G+ P ++ + +P L V G + T LPET G+ ++ ++L Sbjct: 462 IGGILTPLVILLGEYHAALPMLIYGSLPIVAGLLCT--LLPETHGQGLKDTLQDLELGPH 519 Query: 480 PR 481 PR Sbjct: 520 PR 521 >gi|4507001 solute carrier family 22 member 2 [Homo sapiens] Length = 555 Score = 53.9 bits (128), Expect = 3e-07 Identities = 88/420 (20%), Positives = 168/420 (40%), Gaps = 36/420 (8%) Query: 69 MWSLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIM 128 M L S +G G++ G +A GRK LL + +A +L S ++ ++ Sbjct: 148 MLDLFQSSVNVGFFIGSMSIGYIADRFGRKLCLLTTVLINAAAGVLMAISP---TYTWML 204 Query: 129 LGRLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGP 188 + RL+ G+ + I + + E + R V + + +G+++ + G+ L Sbjct: 205 IFRLIQGLVSKAGWLIGYILITEFVGRRYRRTVGIFYQVAYTVGLLV--LAGVAYAL--- 259 Query: 189 QAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSG-DLAGELE 247 W L + +P L +PESPR+L+ + EA + +G L L+ Sbjct: 260 PHWRWLQFTVALPNFFFLLYYWCIPESPRWLISQNKNAEAMRIIKHIAKKNGKSLPASLQ 319 Query: 248 ELEEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAG 307 L E + + P L R + + +++++ + S Y + G Sbjct: 320 RLRLEE---ETGKKLNPSFLDLVRTPQIRKHTMILMYNWFT-----SSVLYQGLIMHM-G 370 Query: 308 VPEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLM--TCWGSIFTVALCLQ 365 + I + E A + + I+R+GRR + C S+F + Sbjct: 371 LAGDNIYLDFFYSALVEFPAAFMIILTIDRIGRRYPWAASNMVAGAACLASVF-----IP 425 Query: 366 SSFPWTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILV 425 W L + ++C+ ++ + ++ EL+ R +C + M + Sbjct: 426 GDLQW-LKIIISCLGRMGITMAYE---IVCLVNAELYPTFIRNLGVHICSS----MCDIG 477 Query: 426 GLGFPFIMEALSH-FLYVPFLGVCVCGAIYTGL--FLPETKGKTFQEISKELHRLNFPRR 482 G+ PF++ L++ +L +P + V G + GL LPETKGK E +E + PR+ Sbjct: 478 GIITPFLVYRLTNIWLELPLMVFGVLGLVAGGLVLLLPETKGKALPETIEEAENMQRPRK 537 >gi|4507005 solute carrier family 22 member 5 [Homo sapiens] Length = 557 Score = 52.8 bits (125), Expect = 7e-07 Identities = 100/435 (22%), Positives = 181/435 (41%), Gaps = 60/435 (13%) Query: 72 LIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGR 131 L +SL+ +G L G+ ++G L+ GRK L V + L FS+ +FEM ++ Sbjct: 144 LTISLFFVGVLLGSFISGQLSDRFGRKNVLFVTMGMQTGFSFLQIFSK---NFEMFVVLF 200 Query: 132 LLVGVNAGVSMNIQPMYLG-ESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGP-- 188 +LVG+ +S + LG E K +R IF+ LG+ + G L P Sbjct: 201 VLVGMGQ-ISNYVAAFVLGTEILGKSVR-------IIFSTLGVCIFYAFGYMVL---PLF 249 Query: 189 ----QAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLA- 243 + W +LL + +PG L +A +PESPR+L+ EA + + + +G + Sbjct: 250 AYFIRDWRMLLVALTMPGVLCVALWWFIPESPRWLISQGRFEEAEVIIRKAAKANGIVVP 309 Query: 244 ------GELEELEEERAACQG-CRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVY 296 EL++L ++ R W + R VT + ++ L SV Sbjct: 310 STIFDPSELQDLSSKKQQSHNILDLLRTWNI-------RMVTIMSIM-----LWMTISVG 357 Query: 297 AYASSVFRKAGVPEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGS 356 + S+ I + E+ V++ ++++ + RR YS+ T Sbjct: 358 YFGLSL--DTPNLHGDIFVNCFLSAMVEVPAYVLAWLLLQYLPRR------YSMATALFL 409 Query: 357 IFTVALCLQSSFPWTLYLAMACIFAFILSFGIGPA-GVTGILATELFDQMARPAACMVCG 415 +V L +Q P YL A + + FG+ A + + EL+ + R V Sbjct: 410 GGSVLLFMQLVPPDLYYL--ATVLVMVGKFGVTAAFSMVYVYTAELYPTVVRNMGVGVSS 467 Query: 416 ALMWIMLILVGLGFPFIMEALSHFLYVPFL---GVCVCGAIYTGLFLPETKGKTFQEISK 472 + IL P+ + ++ ++P++ + + AI T LFLPE+ G + Sbjct: 468 TASRLGSIL----SPYFVYLGAYDRFLPYILMGSLTILTAILT-LFLPESFGTPLPDTID 522 Query: 473 ELHRLNFPRRAQGPT 487 ++ R+ + + P+ Sbjct: 523 QMLRVKGMKHRKTPS 537 >gi|7662270 synaptic vesicle protein 2B homolog [Homo sapiens] Length = 683 Score = 52.8 bits (125), Expect = 7e-07 Identities = 44/153 (28%), Positives = 69/153 (45%), Gaps = 14/153 (9%) Query: 79 LGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGRLLVGVNA 138 LG + GA + G LA LGRK+ L ++ S A L F + G+F + RL+ G+ Sbjct: 156 LGMMAGAFILGGLADKLGRKRVLSMSLAVNASFASLSSFVQGYGAF---LFCRLISGIGI 212 Query: 139 GVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVV--------GLRELLGGP-- 188 G ++ I Y E +E RG IF G + + G +G Sbjct: 213 GGALPIVFAYFSEFLSREKRGEHLSWLGIFWMTGGLYASAMAWSIIPHYGWGFSMGTNYH 272 Query: 189 -QAWPLLLASCLVPGALQLASLPLLPESPRYLL 220 +W + + C +P + + +L +PESPR+LL Sbjct: 273 FHSWRVFVIVCALPCTVSMVALKFMPESPRFLL 305 >gi|216548223 synaptic vesicle glycoprotein 2 [Homo sapiens] Length = 742 Score = 52.4 bits (124), Expect = 1e-06 Identities = 47/157 (29%), Positives = 70/157 (44%), Gaps = 22/157 (14%) Query: 79 LGGLFGALLAGPLAITLGRKKSLL----VNNIFVVSAAILFGFSRKAGSFEMIMLGRLLV 134 LG + GA L G LA LGR++ LL VN++F ++ + G+ G+F + RLL Sbjct: 213 LGMMVGAFLWGGLADRLGRRQCLLISLSVNSVFAFFSSFVQGY----GTF---LFCRLLS 265 Query: 135 GVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVV--------GLRELLG 186 GV G S+ I Y E +E RG +F +G V + G +G Sbjct: 266 GVGIGGSIPIVFSYFSEFLAQEKRGEHLSWLCMFWMIGGVYAAAMAWAIIPHYGWSFQMG 325 Query: 187 GP---QAWPLLLASCLVPGALQLASLPLLPESPRYLL 220 +W + + C P + +L PESPR+ L Sbjct: 326 SAYQFHSWRVFVLVCAFPSVFAIGALTTQPESPRFFL 362 >gi|90669191 solute carrier family 22 member 7 isoform b [Homo sapiens] Length = 548 Score = 51.6 bits (122), Expect = 2e-06 Identities = 103/423 (24%), Positives = 164/423 (38%), Gaps = 57/423 (13%) Query: 80 GGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGRLLVG-VNA 138 G L GA+ G L+ GR++ LLV VS +L S + S+ M + R L G A Sbjct: 154 GVLVGAVAFGYLSDRFGRRRLLLVA---YVSTLVLGLASAASVSYVMFAITRTLTGSALA 210 Query: 139 GVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVG--LRELLGGPQAWPLLLA 196 G ++ + P+ L E E R + S+ F G+++ +VG +R+ W LL Sbjct: 211 GFTIIVMPLEL-EWLDVEHRTVAGVLSSTFWTGGVMLLALVGYLIRD-------WRWLLL 262 Query: 197 SCLVPGALQLASLPLLPESPRYLLIDCGDTEA--CLAALRRLRGSGDLAGELEELEEERA 254 + +P A + SL +PES R+LL EA L RL G + + Sbjct: 263 AVTLPCAPGILSLWWVPESARWLLTQGHVKEAHRYLLHCARLNGRPVCEDSFSQEAVSKV 322 Query: 255 ACQGCRARRP--WELFQHRALRRQVTSLVVL---------GSAMELCGNDSVYAYASSVF 303 A RRP +LF+ LR VV+ G ++++ G +F Sbjct: 323 AAGERVVRRPSYLDLFRTPRLRHISLCCVVVWFGVNFSYYGLSLDVSGLGLNVYQTQLLF 382 Query: 304 RKAGVPEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTV-AL 362 +P + Y + L A G R+L+ S M W ++ V Sbjct: 383 GAVELPSKLLVYLSVRYAGRRLTQAGTLLGTALAFGTRLLV---SSDMKSWSTVLAVMGK 439 Query: 363 CLQSSFPWTLYLAMACIFAFIL-SFGIGPAGVTGILATELFDQMARPAACMVCGALMWIM 421 + T YL + ++ +L G+G + G L L P A ++ G +W+ Sbjct: 440 AFSEAAFTTAYLFTSELYPTVLRQTGMGLTALVGRLGGSL-----APLAALLDG--VWLS 492 Query: 422 LILVGLGFPFIMEALSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLNFPR 481 L + G G+ + A T L LPET+ E +++ R + P Sbjct: 493 LPKLTYG-----------------GIALLAA-GTALLLPETRQAQLPETIQDVERKSAPT 534 Query: 482 RAQ 484 Q Sbjct: 535 SLQ 537 >gi|24497497 solute carrier family 22 member 7 isoform a [Homo sapiens] Length = 546 Score = 51.6 bits (122), Expect = 2e-06 Identities = 103/423 (24%), Positives = 164/423 (38%), Gaps = 57/423 (13%) Query: 80 GGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGRLLVG-VNA 138 G L GA+ G L+ GR++ LLV VS +L S + S+ M + R L G A Sbjct: 152 GVLVGAVAFGYLSDRFGRRRLLLVA---YVSTLVLGLASAASVSYVMFAITRTLTGSALA 208 Query: 139 GVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVG--LRELLGGPQAWPLLLA 196 G ++ + P+ L E E R + S+ F G+++ +VG +R+ W LL Sbjct: 209 GFTIIVMPLEL-EWLDVEHRTVAGVLSSTFWTGGVMLLALVGYLIRD-------WRWLLL 260 Query: 197 SCLVPGALQLASLPLLPESPRYLLIDCGDTEA--CLAALRRLRGSGDLAGELEELEEERA 254 + +P A + SL +PES R+LL EA L RL G + + Sbjct: 261 AVTLPCAPGILSLWWVPESARWLLTQGHVKEAHRYLLHCARLNGRPVCEDSFSQEAVSKV 320 Query: 255 ACQGCRARRP--WELFQHRALRRQVTSLVVL---------GSAMELCGNDSVYAYASSVF 303 A RRP +LF+ LR VV+ G ++++ G +F Sbjct: 321 AAGERVVRRPSYLDLFRTPRLRHISLCCVVVWFGVNFSYYGLSLDVSGLGLNVYQTQLLF 380 Query: 304 RKAGVPEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTV-AL 362 +P + Y + L A G R+L+ S M W ++ V Sbjct: 381 GAVELPSKLLVYLSVRYAGRRLTQAGTLLGTALAFGTRLLV---SSDMKSWSTVLAVMGK 437 Query: 363 CLQSSFPWTLYLAMACIFAFIL-SFGIGPAGVTGILATELFDQMARPAACMVCGALMWIM 421 + T YL + ++ +L G+G + G L L P A ++ G +W+ Sbjct: 438 AFSEAAFTTAYLFTSELYPTVLRQTGMGLTALVGRLGGSL-----APLAALLDG--VWLS 490 Query: 422 LILVGLGFPFIMEALSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLNFPR 481 L + G G+ + A T L LPET+ E +++ R + P Sbjct: 491 LPKLTYG-----------------GIALLAA-GTALLLPETRQAQLPETIQDVERKSAPT 532 Query: 482 RAQ 484 Q Sbjct: 533 SLQ 535 >gi|73695465 synaptic vesicle glycoprotein 2C [Homo sapiens] Length = 727 Score = 48.9 bits (115), Expect = 1e-05 Identities = 43/161 (26%), Positives = 68/161 (42%), Gaps = 22/161 (13%) Query: 75 SLYPLGGLFGALLAGPLAITLGRKKSLL----VNNIFVVSAAILFGFSRKAGSFEMIMLG 130 S+ LG + GA G LA +GRK+SLL VN F ++ + G+ + Sbjct: 195 SIVYLGMMVGAFFWGGLADKVGRKQSLLICMSVNGFFAFLSSFVQGYG-------FFLFC 247 Query: 131 RLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVV--------GLR 182 RLL G G ++ Y E +E RG +F +G + + G Sbjct: 248 RLLSGFGIGGAIPTVFSYFAEVLAREKRGEHLSWLCMFWMIGGIYASAMAWAIIPHYGWS 307 Query: 183 ELLGGP---QAWPLLLASCLVPGALQLASLPLLPESPRYLL 220 +G +W + + C +P + +L +PESPR+LL Sbjct: 308 FSMGSAYQFHSWRVFVIVCALPCVSSVVALTFMPESPRFLL 348 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.327 0.141 0.436 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 18,291,089 Number of Sequences: 37866 Number of extensions: 807405 Number of successful extensions: 2498 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 28 Number of HSP's successfully gapped in prelim test: 25 Number of HSP's that attempted gapping in prelim test: 2391 Number of HSP's gapped (non-prelim): 73 length of query: 499 length of database: 18,247,518 effective HSP length: 106 effective length of query: 393 effective length of database: 14,233,722 effective search space: 5593852746 effective search space used: 5593852746 T: 11 A: 40 X1: 15 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.7 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.