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Search of human proteins with 6754638
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|6754638 microtubule-associated protein tau isoform 2 [Homo
sapiens]
(441 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|6754638 microtubule-associated protein tau isoform 2 [Homo sa... 888 0.0
gi|178557736 microtubule-associated protein tau isoform 5 [Homo ... 814 0.0
gi|8400711 microtubule-associated protein tau isoform 3 [Homo sa... 681 0.0
gi|82534351 microtubule-associated protein tau isoform 1 [Homo s... 608 e-174
gi|178557734 microtubule-associated protein tau isoform 6 [Homo ... 597 e-171
gi|8400715 microtubule-associated protein tau isoform 4 [Homo sa... 592 e-169
gi|87578255 microtubule-associated protein 2 isoform 4 [Homo sap... 328 6e-90
gi|87578394 microtubule-associated protein 2 isoform 5 [Homo sap... 327 1e-89
gi|87578392 microtubule-associated protein 2 isoform 2 [Homo sap... 258 8e-69
gi|87578396 microtubule-associated protein 2 isoform 1 [Homo sap... 251 7e-67
gi|197276600 microtubule-associated protein 4 isoform 4 [Homo sa... 226 3e-59
gi|47519675 microtubule-associated protein 4 isoform 2 [Homo sap... 189 6e-48
gi|47519639 microtubule-associated protein 4 isoform 1 [Homo sap... 189 6e-48
gi|197276602 microtubule-associated protein 4 isoform 5 [Homo sa... 143 4e-34
gi|163965366 nascent polypeptide-associated complex alpha subuni... 58 2e-08
gi|150170670 piccolo isoform 2 [Homo sapiens] 57 4e-08
gi|150378539 piccolo isoform 1 [Homo sapiens] 57 4e-08
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 56 6e-08
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 56 6e-08
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 56 6e-08
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 56 6e-08
gi|113416996 PREDICTED: ankyrin repeat domain 33B [Homo sapiens] 54 3e-07
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 54 4e-07
gi|59806361 hypothetical protein LOC387104 [Homo sapiens] 53 5e-07
gi|149773456 hypothetical protein LOC643314 [Homo sapiens] 52 8e-07
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 51 2e-06
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 50 4e-06
gi|122937267 lemur tyrosine kinase 3 [Homo sapiens] 50 4e-06
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 50 5e-06
gi|31324577 molecule interacting with Rab13 [Homo sapiens] 50 5e-06
>gi|6754638 microtubule-associated protein tau isoform 2 [Homo
sapiens]
Length = 441
Score = 888 bits (2295), Expect = 0.0
Identities = 441/441 (100%), Positives = 441/441 (100%)
Query: 1 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG 60
MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG
Sbjct: 1 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG 60
Query: 61 SETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAG 120
SETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAG
Sbjct: 61 SETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAG 120
Query: 121 HVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPK 180
HVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPK
Sbjct: 121 HVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPK 180
Query: 181 TPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAK 240
TPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAK
Sbjct: 181 TPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAK 240
Query: 241 SRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKHV 300
SRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKHV
Sbjct: 241 SRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKHV 300
Query: 301 PGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNI 360
PGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNI
Sbjct: 301 PGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNI 360
Query: 361 THVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSNVSSTGSIDMV 420
THVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSNVSSTGSIDMV
Sbjct: 361 THVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSNVSSTGSIDMV 420
Query: 421 DSPQLATLADEVSASLAKQGL 441
DSPQLATLADEVSASLAKQGL
Sbjct: 421 DSPQLATLADEVSASLAKQGL 441
>gi|178557736 microtubule-associated protein tau isoform 5 [Homo
sapiens]
Length = 412
Score = 814 bits (2103), Expect = 0.0
Identities = 412/441 (93%), Positives = 412/441 (93%), Gaps = 29/441 (6%)
Query: 1 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG 60
MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG
Sbjct: 1 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG 60
Query: 61 SETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAG 120
SETSDAKSTPTAE AEEAGIGDTPSLEDEAAG
Sbjct: 61 SETSDAKSTPTAE-----------------------------AEEAGIGDTPSLEDEAAG 91
Query: 121 HVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPK 180
HVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPK
Sbjct: 92 HVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPK 151
Query: 181 TPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAK 240
TPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAK
Sbjct: 152 TPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAK 211
Query: 241 SRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKHV 300
SRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKHV
Sbjct: 212 SRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKHV 271
Query: 301 PGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNI 360
PGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNI
Sbjct: 272 PGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNI 331
Query: 361 THVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSNVSSTGSIDMV 420
THVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSNVSSTGSIDMV
Sbjct: 332 THVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSNVSSTGSIDMV 391
Query: 421 DSPQLATLADEVSASLAKQGL 441
DSPQLATLADEVSASLAKQGL
Sbjct: 392 DSPQLATLADEVSASLAKQGL 412
>gi|8400711 microtubule-associated protein tau isoform 3 [Homo
sapiens]
Length = 383
Score = 681 bits (1758), Expect = 0.0
Identities = 340/342 (99%), Positives = 340/342 (99%)
Query: 100 GTTAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAP 159
G AEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAP
Sbjct: 42 GLKAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAP 101
Query: 160 PGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPP 219
PGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPP
Sbjct: 102 PGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPP 161
Query: 220 TREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIIN 279
TREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIIN
Sbjct: 162 TREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIIN 221
Query: 280 KKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEV 339
KKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEV
Sbjct: 222 KKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEV 281
Query: 340 KSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVV 399
KSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVV
Sbjct: 282 KSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVV 341
Query: 400 SGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL 441
SGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL
Sbjct: 342 SGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL 383
>gi|82534351 microtubule-associated protein tau isoform 1 [Homo
sapiens]
Length = 758
Score = 608 bits (1569), Expect = e-174
Identities = 304/331 (91%), Positives = 311/331 (93%)
Query: 111 TPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATR 170
+P++ E V+ +G+ + K KGADGKTKIATPRGAAPPGQKGQANATR
Sbjct: 428 SPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANATR 487
Query: 171 IPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVR 230
IPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVR
Sbjct: 488 IPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVR 547
Query: 231 TPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSK 290
TPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSK
Sbjct: 548 TPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSK 607
Query: 291 CGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRV 350
CGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRV
Sbjct: 608 CGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRV 667
Query: 351 QSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSN 410
QSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSN
Sbjct: 668 QSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSN 727
Query: 411 VSSTGSIDMVDSPQLATLADEVSASLAKQGL 441
VSSTGSIDMVDSPQLATLADEVSASLAKQGL
Sbjct: 728 VSSTGSIDMVDSPQLATLADEVSASLAKQGL 758
Score = 268 bits (686), Expect = 6e-72
Identities = 159/315 (50%), Positives = 179/315 (56%), Gaps = 83/315 (26%)
Query: 1 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG 60
MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG
Sbjct: 1 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG 60
Query: 61 SETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAG 120
SETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAG
Sbjct: 61 SETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAG 120
Query: 121 HVTQ--------------------------------------ARMVSKSKDGTGSDDKKA 142
HVTQ R ++ GTG +D +
Sbjct: 121 HVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAPLLPEGPREATRQPSGTGPEDTEG 180
Query: 143 -----------------------KGADGKTKIATPRGAAPPGQKGQANATR-----IPAK 174
KGA GK + PG K + + R P
Sbjct: 181 GRHAPELLKHQLLGDLHQEGPPLKGAGGKER---------PGSKEEVDEDRDVDESSPQD 231
Query: 175 TPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPK-KVAVVRTPP 233
+PP+ +P G PP++ R S PG P ++P P K + + P
Sbjct: 232 SPPSKASPAQDGRPPQTAAREATSIPGFPA-------EGAIPLPVDFLSKVSTEIPASEP 284
Query: 234 KSPSSAKSRLQTAPV 248
PS +++ Q AP+
Sbjct: 285 DGPSVGRAKGQDAPL 299
>gi|178557734 microtubule-associated protein tau isoform 6 [Homo
sapiens]
Length = 776
Score = 597 bits (1540), Expect = e-171
Identities = 304/349 (87%), Positives = 311/349 (89%), Gaps = 18/349 (5%)
Query: 111 TPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATR 170
+P++ E V+ +G+ + K KGADGKTKIATPRGAAPPGQKGQANATR
Sbjct: 428 SPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANATR 487
Query: 171 IPAKTPPAPKTPPSS------------------GEPPKSGDRSGYSSPGSPGTPGSRSRT 212
IPAKTPPAPKTPPSS GEPPKSGDRSGYSSPGSPGTPGSRSRT
Sbjct: 488 IPAKTPPAPKTPPSSATKQVQRRPPPAGPRSERGEPPKSGDRSGYSSPGSPGTPGSRSRT 547
Query: 213 PSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGG 272
PSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGG
Sbjct: 548 PSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGG 607
Query: 273 GKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKP 332
GKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKP
Sbjct: 608 GKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKP 667
Query: 333 GGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEI 392
GGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEI
Sbjct: 668 GGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEI 727
Query: 393 VYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL 441
VYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL
Sbjct: 728 VYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL 776
Score = 268 bits (686), Expect = 6e-72
Identities = 159/315 (50%), Positives = 179/315 (56%), Gaps = 83/315 (26%)
Query: 1 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG 60
MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG
Sbjct: 1 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG 60
Query: 61 SETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAG 120
SETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAG
Sbjct: 61 SETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAG 120
Query: 121 HVTQ--------------------------------------ARMVSKSKDGTGSDDKKA 142
HVTQ R ++ GTG +D +
Sbjct: 121 HVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAPLLPEGPREATRQPSGTGPEDTEG 180
Query: 143 -----------------------KGADGKTKIATPRGAAPPGQKGQANATR-----IPAK 174
KGA GK + PG K + + R P
Sbjct: 181 GRHAPELLKHQLLGDLHQEGPPLKGAGGKER---------PGSKEEVDEDRDVDESSPQD 231
Query: 175 TPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPK-KVAVVRTPP 233
+PP+ +P G PP++ R S PG P ++P P K + + P
Sbjct: 232 SPPSKASPAQDGRPPQTAAREATSIPGFPA-------EGAIPLPVDFLSKVSTEIPASEP 284
Query: 234 KSPSSAKSRLQTAPV 248
PS +++ Q AP+
Sbjct: 285 DGPSVGRAKGQDAPL 299
>gi|8400715 microtubule-associated protein tau isoform 4 [Homo
sapiens]
Length = 352
Score = 592 bits (1527), Expect = e-169
Identities = 303/342 (88%), Positives = 305/342 (89%), Gaps = 31/342 (9%)
Query: 100 GTTAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAP 159
G AEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAP
Sbjct: 42 GLKAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAP 101
Query: 160 PGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPP 219
PGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPP
Sbjct: 102 PGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPP 161
Query: 220 TREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIIN 279
TREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVK
Sbjct: 162 TREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVK---------------------- 199
Query: 280 KKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEV 339
SK GS +N+KH PGGG VQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEV
Sbjct: 200 ---------SKIGSTENLKHQPGGGKVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEV 250
Query: 340 KSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVV 399
KSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVV
Sbjct: 251 KSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVV 310
Query: 400 SGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL 441
SGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL
Sbjct: 311 SGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL 352
>gi|87578255 microtubule-associated protein 2 isoform 4 [Homo
sapiens]
Length = 502
Score = 328 bits (841), Expect = 6e-90
Identities = 204/475 (42%), Positives = 276/475 (58%), Gaps = 56/475 (11%)
Query: 16 GTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPGSETSDAKSTPTAEDV 75
G G G + G+ +D+EG + E+G G TS + T AE+V
Sbjct: 35 GGAGEGLVRSANGFPYREDEEGAFGEHGSQGTYSNTKENGIN--GELTSADRET--AEEV 90
Query: 76 TAPLVD----------EGAPGKQAAAQPHTEIPEGTTAEEAGIGDTP----------SLE 115
+A +V +G K+A + T E A + +P ++E
Sbjct: 91 SARIVQVVTAEAVAVLKGEQEKEAQHKDQTAALPLAAEETANLPPSPPPSPASEQTVTVE 150
Query: 116 DEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPP--GQKGQ-------- 165
+ A G A V K SD K + ++ + P PP G G
Sbjct: 151 EAAGGESALAPSVFKQAKDKVSDGV-TKSPEKRSSLPRPSSILPPRRGVSGDRDENSFSL 209
Query: 166 ----ANATRIPAKTPP----------APKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSR 211
+++ R ++ P P TP S+ P + +PG+PGTP S R
Sbjct: 210 NSSISSSARRTTRSEPIRRAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTP-SYPR 268
Query: 212 TPSLPTPPTR-----EPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENL 266
TP P P KKVA++RTPPKSP++ K +L+ P+PDLKNVKSKIGST+N+
Sbjct: 269 TPHTPGTPKSAILVPSEKKVAIIRTPPKSPATPK-QLRLINQPLPDLKNVKSKIGSTDNI 327
Query: 267 KHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLG 326
K+QP GG+V+I+NKK+D S VQS+CGSKDNIKH GGG+VQIV K +DLS VTSKCGSL
Sbjct: 328 KYQPKGGQVRILNKKIDFSKVQSRCGSKDNIKHSAGGGNVQIVTKKIDLSHVTSKCGSLK 387
Query: 327 NIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKT 386
NI H+PGGG+V+++S KLDFK++ Q+K+GSLDN HVPGGGN KI++ KL FRE+AKA+
Sbjct: 388 NIRHRPGGGRVKIESVKLDFKEKAQAKVGSLDNAHHVPGGGNVKIDSQKLNFREHAKARV 447
Query: 387 DHGAEIVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL 441
DHGAEI+ +SP S SPR LSNVSS+GSI++++SPQLATLA++V+A+LAKQGL
Sbjct: 448 DHGAEIITQSPGRSSVASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL 502
>gi|87578394 microtubule-associated protein 2 isoform 5 [Homo
sapiens]
Length = 559
Score = 327 bits (838), Expect = 1e-89
Identities = 203/460 (44%), Positives = 273/460 (59%), Gaps = 52/460 (11%)
Query: 25 DQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPGSE-TSDAKSTPTAEDVTAPLVDEG 83
+Q H+DQ +E+ P+ S P SE T + E AP V +
Sbjct: 109 EQEKEAQHKDQTAALPLAAEETANLPPSPPPS--PASEQTVTVEEAAGGESALAPSVFKQ 166
Query: 84 APGKQA--------AAQPHTEIPE-----GTTAEEAGIGDTPSLEDEAAGHVTQARMVSK 130
A K + A Q T+ P +T + A D+ ++ +AG T SK
Sbjct: 167 AKDKVSNSTLSKIPALQGSTKSPRYSSACPSTTKRATFSDSLLIQPTSAGS-TDRLPYSK 225
Query: 131 SKDGTGSDDKKAKGADGKTKIATPRGAAPP--GQKGQ------------ANATRIPAKTP 176
S G+ D K + ++ + P PP G G +++ R ++
Sbjct: 226 S----GNKDGVTKSPEKRSSLPRPSSILPPRRGVSGDRDENSFSLNSSISSSARRTTRSE 281
Query: 177 P----------APKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTR----- 221
P P TP S+ P + +PG+PGTP S RTP P P
Sbjct: 282 PIRRAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTP-SYPRTPHTPGTPKSAILVP 340
Query: 222 EPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKK 281
KKVA++RTPPKSP++ K +L+ P+PDLKNVKSKIGST+N+K+QP GG+V+I+NKK
Sbjct: 341 SEKKVAIIRTPPKSPATPK-QLRLINQPLPDLKNVKSKIGSTDNIKYQPKGGQVRILNKK 399
Query: 282 LDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKS 341
+D S VQS+CGSKDNIKH GGG+VQIV K +DLS VTSKCGSL NI H+PGGG+V+++S
Sbjct: 400 IDFSKVQSRCGSKDNIKHSAGGGNVQIVTKKIDLSHVTSKCGSLKNIRHRPGGGRVKIES 459
Query: 342 EKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSG 401
KLDFK++ Q+K+GSLDN HVPGGGN KI++ KL FRE+AKA+ DHGAEI+ +SP S
Sbjct: 460 VKLDFKEKAQAKVGSLDNAHHVPGGGNVKIDSQKLNFREHAKARVDHGAEIITQSPGRSS 519
Query: 402 DTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL 441
SPR LSNVSS+GSI++++SPQLATLA++V+A+LAKQGL
Sbjct: 520 VASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL 559
>gi|87578392 microtubule-associated protein 2 isoform 2 [Homo
sapiens]
Length = 471
Score = 258 bits (659), Expect = 8e-69
Identities = 180/475 (37%), Positives = 245/475 (51%), Gaps = 87/475 (18%)
Query: 16 GTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPGSETSDAKSTPTAEDV 75
G G G + G+ +D+EG + E+G G TS + T AE+V
Sbjct: 35 GGAGEGLVRSANGFPYREDEEGAFGEHGSQGTYSNTKENGIN--GELTSADRET--AEEV 90
Query: 76 TAPLVD----------EGAPGKQAAAQPHTEIPEGTTAEEAGIGDTP----------SLE 115
+A +V +G K+A + T E A + +P ++E
Sbjct: 91 SARIVQVVTAEAVAVLKGEQEKEAQHKDQTAALPLAAEETANLPPSPPPSPASEQTVTVE 150
Query: 116 DEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPP--GQKGQ-------- 165
+ A G A V K SD K + ++ + P PP G G
Sbjct: 151 EAAGGESALAPSVFKQAKDKVSDGV-TKSPEKRSSLPRPSSILPPRRGVSGDRDENSFSL 209
Query: 166 ----ANATRIPAKTPP----------APKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSR 211
+++ R ++ P P TP S+ P + +PG+PGTP S R
Sbjct: 210 NSSISSSARRTTRSEPIRRAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTP-SYPR 268
Query: 212 TPSLPTPPTR-----EPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENL 266
TP P P KKVA++RTPPKSP++ K +L+ P+PDLK
Sbjct: 269 TPHTPGTPKSAILVPSEKKVAIIRTPPKSPATPK-QLRLINQPLPDLK------------ 315
Query: 267 KHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLG 326
NV+SK GS DNIK+ P GG VQIV K +DLS VTSKCGSL
Sbjct: 316 -------------------NVKSKIGSTDNIKYQPKGGQVQIVTKKIDLSHVTSKCGSLK 356
Query: 327 NIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKT 386
NI H+PGGG+V+++S KLDFK++ Q+K+GSLDN HVPGGGN KI++ KL FRE+AKA+
Sbjct: 357 NIRHRPGGGRVKIESVKLDFKEKAQAKVGSLDNAHHVPGGGNVKIDSQKLNFREHAKARV 416
Query: 387 DHGAEIVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL 441
DHGAEI+ +SP S SPR LSNVSS+GSI++++SPQLATLA++V+A+LAKQGL
Sbjct: 417 DHGAEIITQSPGRSSVASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL 471
>gi|87578396 microtubule-associated protein 2 isoform 1 [Homo sapiens]
Length = 1827
Score = 251 bits (642), Expect = 7e-67
Identities = 147/288 (51%), Positives = 184/288 (63%), Gaps = 53/288 (18%)
Query: 161 GQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSS--PGSPGTPGSRSRTPSLPTP 218
G+ G + T P T P TPPS YSS PG+PGTP S RTP P
Sbjct: 1586 GKSGTSTPTT-PGSTAITPGTPPS------------YSSRTPGTPGTP-SYPRTPHTPGT 1631
Query: 219 PTR-----EPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGG 273
P KKVA++RTPPKSP++ K +L+ P+PDLK
Sbjct: 1632 PKSAILVPSEKKVAIIRTPPKSPATPK-QLRLINQPLPDLK------------------- 1671
Query: 274 KVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPG 333
NV+SK GS DNIK+ P GG VQIV K +DLS VTSKCGSL NI H+PG
Sbjct: 1672 ------------NVKSKIGSTDNIKYQPKGGQVQIVTKKIDLSHVTSKCGSLKNIRHRPG 1719
Query: 334 GGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIV 393
GG+V+++S KLDFK++ Q+K+GSLDN HVPGGGN KI++ KL FRE+AKA+ DHGAEI+
Sbjct: 1720 GGRVKIESVKLDFKEKAQAKVGSLDNAHHVPGGGNVKIDSQKLNFREHAKARVDHGAEII 1779
Query: 394 YKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL 441
+SP S SPR LSNVSS+GSI++++SPQLATLA++V+A+LAKQGL
Sbjct: 1780 TQSPGRSSVASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL 1827
>gi|197276600 microtubule-associated protein 4 isoform 4 [Homo
sapiens]
Length = 1135
Score = 226 bits (576), Expect = 3e-59
Identities = 149/409 (36%), Positives = 204/409 (49%), Gaps = 68/409 (16%)
Query: 39 TDAGLKESPLQTPTEDGSEEPGSETSDAKSTPT---AEDVTA-PLVDEGAPGKQAAAQPH 94
T GL + P+ + P + A + P+ ++DV P+ D AP K+A+
Sbjct: 732 TIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSK- 790
Query: 95 TEIPEGTTAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDK----KAKGADGKTK 150
P A +G T ++ + S T K K +G + K
Sbjct: 791 ---PASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVK 847
Query: 151 IATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRS 210
T + + ++ +T KT T P++G P S + P S
Sbjct: 848 KMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVP--------SRVKATPMPSRPS 899
Query: 211 RTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQP 270
TP + PT P S + SRL T PDLKNV+SK+GSTEN+KHQP
Sbjct: 900 TTPFIDKKPTS---------AKPSSTTPRLSRLATN-TSAPDLKNVRSKVGSTENIKHQP 949
Query: 271 GGG--------------------------------------KVQIINKKLDLSNVQSKCG 292
GGG KVQI++KK+ S++QSKCG
Sbjct: 950 GGGRAKVEKKTEAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCG 1009
Query: 293 SKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQS 352
SKDNIKHVPGGG+VQI K VD+SKV+SKCGS NI HKPGGG V+++S+KL+FK++ Q+
Sbjct: 1010 SKDNIKHVPGGGNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQA 1069
Query: 353 KIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSG 401
K+GSLDN+ H+P GG KIET++LTFR NA+A+TDHGA+IV + P G
Sbjct: 1070 KVGSLDNVGHLPAGGAVKIETYRLTFRANARARTDHGADIVSRPPHFPG 1118
Score = 33.9 bits (76), Expect = 0.30
Identities = 42/201 (20%), Positives = 69/201 (34%), Gaps = 23/201 (11%)
Query: 59 PGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEA 118
P E + + A APL +G P ++P P E EA
Sbjct: 538 PEMEVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVP-------------PLSETEA 584
Query: 119 AGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPA 178
+ +++++ G D D A +P G +PA+
Sbjct: 585 TPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSV 644
Query: 179 -----PKTPPSSGEPPKSGDRSGYSSP--GSP---GTPGSRSRTPSLPTPPTREPKKVAV 228
+ P +S S + SG + P G P GT + P+ PP+ E K +
Sbjct: 645 LEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPL 704
Query: 229 VRTPPKSPSSAKSRLQTAPVP 249
T P S++K++ Q +P
Sbjct: 705 ATTQPAKTSTSKAKTQPTSLP 725
>gi|47519675 microtubule-associated protein 4 isoform 2 [Homo
sapiens]
Length = 887
Score = 189 bits (479), Expect = 6e-48
Identities = 131/380 (34%), Positives = 180/380 (47%), Gaps = 68/380 (17%)
Query: 39 TDAGLKESPLQTPTEDGSEEPGSETSDAKSTPT---AEDVTA-PLVDEGAPGKQAAAQPH 94
T GL + P+ + P + A + P+ ++DV P+ D AP K+A+
Sbjct: 467 TIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSK- 525
Query: 95 TEIPEGTTAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDK----KAKGADGKTK 150
P A +G T ++ + S T K K +G + K
Sbjct: 526 ---PASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVK 582
Query: 151 IATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRS 210
T + + ++ +T KT T P++G P S + P S
Sbjct: 583 KMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVP--------SRVKATPMPSRPS 634
Query: 211 RTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQP 270
TP + PT P S + SRL T PDLKNV+SK+GSTEN+KHQP
Sbjct: 635 TTPFIDKKPTS---------AKPSSTTPRLSRLATN-TSAPDLKNVRSKVGSTENIKHQP 684
Query: 271 GGG--------------------------------------KVQIINKKLDLSNVQSKCG 292
GGG KVQI++KK+ S++QSKCG
Sbjct: 685 GGGRAKVEKKTEAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCG 744
Query: 293 SKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQS 352
SKDNIKHVPGGG+VQI K VD+SKV+SKCGS NI HKPGGG V+++S+KL+FK++ Q+
Sbjct: 745 SKDNIKHVPGGGNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQA 804
Query: 353 KIGSLDNITHVPGGGNKKIE 372
K+GSLDN+ H+P GG K E
Sbjct: 805 KVGSLDNVGHLPAGGAVKTE 824
Score = 43.5 bits (101), Expect = 4e-04
Identities = 36/132 (27%), Positives = 56/132 (42%), Gaps = 16/132 (12%)
Query: 123 TQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTP 182
T +M KS+ T + KK + K+++A P KG T+ TP PK+
Sbjct: 340 TPQKMTEKSESKTPGEGKK----EDKSRMAEP-------MKGYMRPTKSRGLTPLLPKST 388
Query: 183 PSSGEPPKSGDRSGYSSP--GSP---GTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPS 237
E K +G + P G P GT + P+ PP+ E K + T P S
Sbjct: 389 IQEQERHKQLKSAGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTS 448
Query: 238 SAKSRLQTAPVP 249
++K++ Q +P
Sbjct: 449 TSKAKTQPTSLP 460
>gi|47519639 microtubule-associated protein 4 isoform 1 [Homo sapiens]
Length = 1152
Score = 189 bits (479), Expect = 6e-48
Identities = 131/380 (34%), Positives = 180/380 (47%), Gaps = 68/380 (17%)
Query: 39 TDAGLKESPLQTPTEDGSEEPGSETSDAKSTPT---AEDVTA-PLVDEGAPGKQAAAQPH 94
T GL + P+ + P + A + P+ ++DV P+ D AP K+A+
Sbjct: 732 TIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSK- 790
Query: 95 TEIPEGTTAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDK----KAKGADGKTK 150
P A +G T ++ + S T K K +G + K
Sbjct: 791 ---PASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVK 847
Query: 151 IATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRS 210
T + + ++ +T KT T P++G P S + P S
Sbjct: 848 KMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVP--------SRVKATPMPSRPS 899
Query: 211 RTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQP 270
TP + PT P S + SRL T PDLKNV+SK+GSTEN+KHQP
Sbjct: 900 TTPFIDKKPTS---------AKPSSTTPRLSRLATN-TSAPDLKNVRSKVGSTENIKHQP 949
Query: 271 GGG--------------------------------------KVQIINKKLDLSNVQSKCG 292
GGG KVQI++KK+ S++QSKCG
Sbjct: 950 GGGRAKVEKKTEAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCG 1009
Query: 293 SKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQS 352
SKDNIKHVPGGG+VQI K VD+SKV+SKCGS NI HKPGGG V+++S+KL+FK++ Q+
Sbjct: 1010 SKDNIKHVPGGGNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQA 1069
Query: 353 KIGSLDNITHVPGGGNKKIE 372
K+GSLDN+ H+P GG K E
Sbjct: 1070 KVGSLDNVGHLPAGGAVKTE 1089
Score = 33.9 bits (76), Expect = 0.30
Identities = 42/201 (20%), Positives = 69/201 (34%), Gaps = 23/201 (11%)
Query: 59 PGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEA 118
P E + + A APL +G P ++P P E EA
Sbjct: 538 PEMEVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVP-------------PLSETEA 584
Query: 119 AGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPA 178
+ +++++ G D D A +P G +PA+
Sbjct: 585 TPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSV 644
Query: 179 -----PKTPPSSGEPPKSGDRSGYSSP--GSP---GTPGSRSRTPSLPTPPTREPKKVAV 228
+ P +S S + SG + P G P GT + P+ PP+ E K +
Sbjct: 645 LEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPL 704
Query: 229 VRTPPKSPSSAKSRLQTAPVP 249
T P S++K++ Q +P
Sbjct: 705 ATTQPAKTSTSKAKTQPTSLP 725
>gi|197276602 microtubule-associated protein 4 isoform 5 [Homo
sapiens]
Length = 817
Score = 143 bits (360), Expect = 4e-34
Identities = 114/350 (32%), Positives = 153/350 (43%), Gaps = 50/350 (14%)
Query: 44 KESPLQTPTEDGSEEPGSETSDAKSTPTA-----------------EDVTAPLVDEGAPG 86
K PL T ++ + TS AK+ PT+ + + LV P
Sbjct: 435 KTKPLAT-----TQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPK 489
Query: 87 KQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGAD 146
+ A A I + I D + E A+ + S+S +K
Sbjct: 490 RPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSG---------SKSTQ 540
Query: 147 GKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRS---GYSSPGSP 203
K T A G ++ +T +P K P A KT E K +S S P S
Sbjct: 541 TVAKTTTAAAVASTGPSSRSPSTLLPKK-PTAIKTEGKPAEVKKMTAKSVPADLSRPKST 599
Query: 204 GTPGSRSRTPSLPTPPTREPKKVAVVRTP-PKSPSSAKSRLQTAPVPMPDLKNVKSKIGS 262
T + T T P V TP P PS+ P D K +K S
Sbjct: 600 STSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTT---------PFIDKKPTSAKPSS 650
Query: 263 TENLKHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKC 322
T P ++ DL NV+SK GS +NIKH PGGG VQI K VD+SKV+SKC
Sbjct: 651 TT-----PRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRVQIQNKKVDISKVSSKC 705
Query: 323 GSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIE 372
GS NI HKPGGG V+++S+KL+FK++ Q+K+GSLDN+ H+P GG K E
Sbjct: 706 GSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTE 755
Score = 98.2 bits (243), Expect = 1e-20
Identities = 93/336 (27%), Positives = 136/336 (40%), Gaps = 37/336 (11%)
Query: 81 DEGAP-----GKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGT 135
+EG P G P+ E+P + + T + + TQ + K T
Sbjct: 407 EEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPT 466
Query: 136 ---GSDDKKAKGADGKTKIATPRGAAPPGQKGQANATR-------IPAKTPPAPKTP--P 183
G + K A G A P+ A + ++ AK P +P P
Sbjct: 467 TIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKP 526
Query: 184 SSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRL 243
+S +SG +S + + S PS +P T PKK ++T K K
Sbjct: 527 ASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTA 586
Query: 244 QTAPVPMPDLKNVKSKIGSTENLKHQ-------PGGGKVQIINKKLDLSN-------VQS 289
++ P DL KS ST ++K P G V K + + +
Sbjct: 587 KSVPA---DLSRPKST--STSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDK 641
Query: 290 KCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDR 349
K S P + DL V SK GS NI H+PGGG+V+++++K+D +
Sbjct: 642 KPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRVQIQNKKVDIS-K 700
Query: 350 VQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAK 385
V SK GS NI H PGGG+ KIE+ KL F+E A+AK
Sbjct: 701 VSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAK 736
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 57.8 bits (138), Expect = 2e-08
Identities = 69/234 (29%), Positives = 83/234 (35%), Gaps = 51/234 (21%)
Query: 44 KESPLQTPTEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTA 103
K SP TP G+ P + T + P PL +GAP AA P P+G A
Sbjct: 1020 KGSPAATPFPKGASTPPAATPPS---PKGSPAATPL-PKGAPTTPAATLPS---PKGGPA 1072
Query: 104 EEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGA---------DGKTKIATP 154
TPSL+ G T S G G KGA K +ATP
Sbjct: 1073 -------TPSLK----GAPTPPAATPPSPKG-GPATPSPKGAPMPPAATPPSPKGGLATP 1120
Query: 155 R--------GAAPPGQKG------QANATRIPAKTPPAPK----TPPSSGEPPKSG---- 192
A PP KG A PA TPP+PK TPP G P
Sbjct: 1121 PHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPP 1180
Query: 193 -DRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQT 245
+ G ++P G P + + TP P P TP +P S K L T
Sbjct: 1181 SPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLAT 1234
Score = 57.8 bits (138), Expect = 2e-08
Identities = 71/250 (28%), Positives = 94/250 (37%), Gaps = 47/250 (18%)
Query: 42 GLKESPLQTPT--EDGSEEP---GSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPH-- 94
G +P TP + G P G+ T+ A + P+ + A +GAP AA P
Sbjct: 1193 GAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPK 1252
Query: 95 ----TEIPEGTTAEEAGIGDTPSLEDEAA-----GHVTQARMVSKSKDGTGSDDKKAKGA 145
T P+G A PSL+ A G A + S G G KGA
Sbjct: 1253 GGPATPPPKGAPTPPAAT--PPSLKGGLATPPHKGAPNPAVVTPPSPKG-GPATSPPKGA 1309
Query: 146 DGKTKIATPRGAAPPGQKGQAN------ATRIPAKTPPAPK--------TPPSSGEPPKS 191
TP A PP KG A PA TPP+PK TP S G P
Sbjct: 1310 P------TPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTP 1363
Query: 192 GDRSGYSSP-------GSPG-TPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRL 243
+ G + P G P TP S R P++P+P + +P K+P++ +R
Sbjct: 1364 SSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTRE 1423
Query: 244 QTAPVPMPDL 253
A DL
Sbjct: 1424 GAATPSKGDL 1433
Score = 55.8 bits (133), Expect = 7e-08
Identities = 66/243 (27%), Positives = 86/243 (35%), Gaps = 48/243 (19%)
Query: 35 QEGDTDAGLKESPLQTPTEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPH 94
+EG K++P + T S A++TP + + A +GAP AA P
Sbjct: 897 KEGPATPAPKQAPALSMTS-------SSPKKARATPAPKGIPASPSPKGAPTPPAATPPS 949
Query: 95 TE-------------IPEGTTAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKK 141
+ P T G TPS + G T S G G
Sbjct: 950 PKGGPATPSPKWAPTPPAATPPSPKGGPATPSPK----GAPTPPAATPPSPKG-GPATPS 1004
Query: 142 AKGADGKTKIATPRGAAPPGQKGQANATRIP-------AKTPPAPKTPPSSGEPPKSGDR 194
KGA TP PP KG AT P A TPP+PK P++ PK
Sbjct: 1005 PKGAP------TPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPT 1058
Query: 195 SGY----SSPGSPGTPGSR-SRTPSLPTPPTRE-----PKKVAVVRTPPKSPSSAKSRLQ 244
+ S G P TP + + TP TPP+ + P P +P S K L
Sbjct: 1059 TPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLA 1118
Query: 245 TAP 247
T P
Sbjct: 1119 TPP 1121
Score = 55.1 bits (131), Expect = 1e-07
Identities = 55/219 (25%), Positives = 70/219 (31%), Gaps = 26/219 (11%)
Query: 46 SPLQTPTEDGSEEP----GSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGT 101
SP PT + P G T K PT T P G P T P+G
Sbjct: 958 SPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGG---------PATPSPKGA 1008
Query: 102 TAEEAGIGDTPSLEDEAA----GHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGA 157
A +P A G T S G+ + KGA P
Sbjct: 1009 PTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPK 1068
Query: 158 APPGQKGQANATRIPAKTPPAPKTPPSSGEPPKS---------GDRSGYSSPGSPGTPGS 208
P A PA TPP+PK P++ P + + G ++P G P +
Sbjct: 1069 GGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTT 1128
Query: 209 RSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAP 247
+ TP P P TP +P S K L T P
Sbjct: 1129 PAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPP 1167
Score = 55.1 bits (131), Expect = 1e-07
Identities = 56/228 (24%), Positives = 72/228 (31%), Gaps = 18/228 (7%)
Query: 30 TMHQDQEGDTDAGLKESPLQTPTEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQA 89
T+ + G LK +P S + G T K P T P +P
Sbjct: 1063 TLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPP-----SPKGGL 1117
Query: 90 AAQPHTEIPEGTTAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKT 149
A PH P A + T A K G + K
Sbjct: 1118 ATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAA 1177
Query: 150 KIATPRGA-APPGQKGQANATRIPAKTPPAPK----TPPSSGEP-----PKSGDRSGYSS 199
+P+G A P KG A PA TPP+PK TP G P + G ++
Sbjct: 1178 TPPSPKGGLATPSPKG---APTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLAT 1234
Query: 200 PGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAP 247
P G P + + TP P P P +P S K L T P
Sbjct: 1235 PSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPP 1282
Score = 54.3 bits (129), Expect = 2e-07
Identities = 64/224 (28%), Positives = 80/224 (35%), Gaps = 20/224 (8%)
Query: 42 GLKESPLQTPT--EDGSEEP---GSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPH-- 94
G +P TP + G P G+ T+ A + P+ + A +GAP AA P
Sbjct: 1170 GAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPK 1229
Query: 95 ----TEIPEGTTAEEAGIGDTPS---LEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADG 147
T P+G A +P G T S G G KGA
Sbjct: 1230 GGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKG-GLATPPHKGAPN 1288
Query: 148 KTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSP-GTP 206
+ P P A PA TPP+PK P + PPK +P SP GTP
Sbjct: 1289 PAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGT-PPPKGAPTPPAVTPPSPKGTP 1347
Query: 207 GSRSRTPSLPTPPTREPKKVAVVRTPP-KSPSSAKSRLQTAPVP 249
+ TPS PT K TPP +PS T P P
Sbjct: 1348 TLPATTPSSKGGPTTPSSKEG--PTPPAATPSHKGGPAMTPPSP 1389
Score = 53.1 bits (126), Expect = 5e-07
Identities = 61/244 (25%), Positives = 86/244 (35%), Gaps = 17/244 (6%)
Query: 33 QDQEGDTDAGLKESPLQTPTEDGSE--EPGSETSDAKSTPTAEDVTAPLVDEG----APG 86
+D T + SP PT P T K TPT V P EG AP
Sbjct: 847 KDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPK 906
Query: 87 KQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGAD 146
+ A + P+ A A G S + A A S K A
Sbjct: 907 QAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPP 966
Query: 147 GKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTP 206
T + G A P KG A PA TPP+PK P++ P + + P G+P
Sbjct: 967 AATPPSPKGGPATPSPKG---APTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSP 1023
Query: 207 GSR-----SRTPSLPTPPTRE--PKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSK 259
+ + TP TPP+ + P + + P +P++ + P P LK +
Sbjct: 1024 AATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPA-TPSLKGAPTP 1082
Query: 260 IGST 263
+T
Sbjct: 1083 PAAT 1086
Score = 53.1 bits (126), Expect = 5e-07
Identities = 68/265 (25%), Positives = 93/265 (35%), Gaps = 36/265 (13%)
Query: 48 LQTPTEDGSEEP----------GSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEI 97
L TP G+ P G TS K PT T P +G+PG T
Sbjct: 1278 LATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPS-PKGSPGTPPPKGAPTP- 1335
Query: 98 PEGTTAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGA 157
P T G P+ + G T SK + KG T + RG
Sbjct: 1336 PAVTPPSPKGTPTLPATTPSSKGGPTTPS--SKEGPTPPAATPSHKGGPAMTPPSPKRGP 1393
Query: 158 APPGQKGQANATRI----PAKTPPAPKT-----PPSSGE--PPKSGDRSGYSSP------ 200
A P KG + + P K P P T PS G+ PP S +P
Sbjct: 1394 AIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPK 1453
Query: 201 GSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNV---- 256
G P TP S+ P+LP PK+ + S S K+ AP+ P L V
Sbjct: 1454 GGPATPSSKG-DPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSS 1512
Query: 257 KSKIGSTENLKHQPGGGKVQIINKK 281
++ +T + + P +++KK
Sbjct: 1513 PKEVPATPSSRRDPIAPTATLLSKK 1537
Score = 46.6 bits (109), Expect = 5e-05
Identities = 65/228 (28%), Positives = 85/228 (37%), Gaps = 49/228 (21%)
Query: 26 QGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEE---PGSETSDAKSTPTAEDVTAPLVDE 82
+GG T +EG T P TP+ G P + A +P D T+P V
Sbjct: 1357 KGGPTTPSSKEGPTP------PAATPSHKGGPAMTPPSPKRGPAIPSPKG-DPTSPAVIP 1409
Query: 83 GAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKA 142
+P K+A A P T EG TPS D VT + KKA
Sbjct: 1410 LSP-KKAPATPVTR--EGAA--------TPSKGDLTPPAVTPVSL------------KKA 1446
Query: 143 KGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSP-G 201
A G A P KG +PA TPP+PK EPP + SSP
Sbjct: 1447 PATS-----APKGGPATPSSKGDPT---LPAVTPPSPK------EPPAPKQVATSSSPKK 1492
Query: 202 SPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVP 249
+P TP P+LP PK+V + + P + + L + P
Sbjct: 1493 APATPAPMG-APTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTP 1539
Score = 45.4 bits (106), Expect = 1e-04
Identities = 63/257 (24%), Positives = 82/257 (31%), Gaps = 51/257 (19%)
Query: 39 TDAGLKESPLQTPTEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQ------ 92
T LK++P + + G P S K PT VT P E KQ A
Sbjct: 1439 TPVSLKKAPATSAPKGGPATPSS-----KGDPTLPAVTPPSPKEPPAPKQVATSSSPKKA 1493
Query: 93 PHTEIPEGTTAEEAGIGDTP--------SLEDEAAGHVT-------------------QA 125
P T P G A I +P S D A T
Sbjct: 1494 PATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAM 1553
Query: 126 RMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRI---PAKTPPAPKTP 182
+ S K K+A + ++P P KG + + PA T P+PK
Sbjct: 1554 TVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEA 1613
Query: 183 PSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPS----LPTPPTREPKKV------AVVRTP 232
P+ G ++P GTP S TPS PT P K+ A P
Sbjct: 1614 PTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLP 1673
Query: 233 PKSPSSAKSRLQTAPVP 249
K +A + AP P
Sbjct: 1674 AKKGPTALKEVLVAPAP 1690
Score = 43.1 bits (100), Expect = 5e-04
Identities = 58/234 (24%), Positives = 86/234 (36%), Gaps = 22/234 (9%)
Query: 39 TDAGLKESPLQTPTEDGSEEPGSETSDAKSTPTAEDVT-APLVDEGAPGKQAAAQPHTEI 97
T KE+P S E G T K TPT+ VT + L D + +
Sbjct: 1606 TSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATV 1665
Query: 98 PEGTTAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGA 157
P+ + A G T +L++ ++ + + G KK+ + P +
Sbjct: 1666 PQASKGLPAKKGPT-ALKEVLVAPAPESTPIITAPTRKGPQTKKSSAT---SPPICPDPS 1721
Query: 158 APPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPT 217
A G KG +T PA P K S + K D S +S G P S++ TP
Sbjct: 1722 AKNGSKGPL-STVAPAPLLPVQK---DSSKTAKGKDAS-HSPKGPLAPPESKASTPLTAA 1776
Query: 218 P-----PTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENL 266
P E V+ +PP S L AP P+P L + + S+ L
Sbjct: 1777 AFEKVLPKPESASVSAAPSPPVS-------LPLAPSPVPTLPPKQQFLPSSPGL 1823
Score = 42.4 bits (98), Expect = 9e-04
Identities = 60/259 (23%), Positives = 95/259 (36%), Gaps = 32/259 (12%)
Query: 41 AGLKESPLQTP-TEDGSEEPGSETSD--AKSTPTA----EDVTAPLVDEGAPGKQAAAQP 93
A + SP + P T +P + T+ +K TP E + P + +P K A
Sbjct: 1507 AVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPT 1566
Query: 94 HTEIPEGTTAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIAT 153
E P +++EA P++ + + T K+A T +
Sbjct: 1567 PKEAPATPSSKEAS--SPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSP 1624
Query: 154 PRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPP--KSGDRSGYSSPGSPGTPGSRS- 210
+G A P KG + P TP + K P+S K G +S G P G +
Sbjct: 1625 EKGPATPAPKGTPTS---PPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTAL 1681
Query: 211 ----------RTPSLPTPPTREP--KKVAVVRTP----PKSPSSAKSRLQT-APVPMPDL 253
TP + P + P KK + P P + + +K L T AP P+ +
Sbjct: 1682 KEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPV 1741
Query: 254 KNVKSKIGSTENLKHQPGG 272
+ SK ++ H P G
Sbjct: 1742 QKDSSKTAKGKDASHSPKG 1760
Score = 30.4 bits (67), Expect = 3.3
Identities = 22/88 (25%), Positives = 38/88 (43%), Gaps = 9/88 (10%)
Query: 164 GQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREP 223
G+A T +PA P+ + P S S ++ G PG P+LP P + P
Sbjct: 3 GEATET-VPATEQELPQPQAETAVLPMSSALSVTAALGQPG--------PTLPPPCSPAP 53
Query: 224 KKVAVVRTPPKSPSSAKSRLQTAPVPMP 251
++ + SP + S + + P+ +P
Sbjct: 54 QQCPLSAANQASPFPSPSTIASTPLEVP 81
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 56.6 bits (135), Expect = 4e-08
Identities = 55/224 (24%), Positives = 82/224 (36%), Gaps = 13/224 (5%)
Query: 52 TEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQ-PHTEIP-EGTTAEEAGIG 109
T+ +++PG+ + T + PL P +Q ++ P +E P A+ G+G
Sbjct: 339 TKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVG 398
Query: 110 DTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPR---GAAPPGQKG-- 164
TP+ + A TQ K AK A G TK + G P Q G
Sbjct: 399 KTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAK-APGPTKTPVQQPGPGKIPAQQAGPG 457
Query: 165 -----QANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPP 219
Q T+ P++ P K PP P K + S+ PGS P P P
Sbjct: 458 KTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPA 517
Query: 220 TREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGST 263
P++ + P + P SAK Q P + + T
Sbjct: 518 KPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQT 561
Score = 53.9 bits (128), Expect = 3e-07
Identities = 65/243 (26%), Positives = 85/243 (34%), Gaps = 44/243 (18%)
Query: 47 PLQTPT--EDGSEEPGSETSD---AKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGT 101
P+Q PT + +++PG E S AK +T PL + K P T P
Sbjct: 305 PIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPP-- 362
Query: 102 TAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPG 161
A+ G P+ Q S + G GKT P A PP
Sbjct: 363 -AQPLGPAKPPA---------QQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPT 412
Query: 162 QK-------GQANATRIPAKTPPAPKTP---PSSGEPPKSGDRSGYSSPGSPGTPGSRSR 211
Q+ Q + PAK P KTP P G+ P G +S G S+
Sbjct: 413 QQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQ 472
Query: 212 TPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPG 271
P PP ++P + PP+ P SAK P P GST+ QPG
Sbjct: 473 LPGPAKPPPQQP---GPAKPPPQQPGSAKP-----PSQQP---------GSTKPPPQQPG 515
Query: 272 GGK 274
K
Sbjct: 516 PAK 518
Score = 43.9 bits (102), Expect = 3e-04
Identities = 65/252 (25%), Positives = 97/252 (38%), Gaps = 45/252 (17%)
Query: 47 PLQTPTED-GSEEPGSETSDAKS---------TPTAEDVTA--PLVDEGAPGKQAAAQPH 94
P + P + GSE+P SE K+ TP + A P G P K A QP
Sbjct: 368 PAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTP-KPLAQQPG 426
Query: 95 TEIPEG------TTAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGK 148
+ P T ++ G G P+ +A T A+ +K + K
Sbjct: 427 LQSPAKAPGPTKTPVQQPGPGKIPA--QQAGPGKTSAQQTGPTKPPSQLP------GPAK 478
Query: 149 TKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPK-SGDRSGYSSPGS--PGT 205
P A PP Q Q + + P++ P + K PP P K S + G + P S PG+
Sbjct: 479 PPPQQPGPAKPPPQ--QPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGS 536
Query: 206 --PGSRSRTPSLP-----TPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKS 258
P ++ +P+ P T P + ++ P SPS+ + Q P K +
Sbjct: 537 AKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLP------KTICP 590
Query: 259 KIGSTENLKHQP 270
+TE L H P
Sbjct: 591 LCNTTELLLHVP 602
Score = 40.4 bits (93), Expect = 0.003
Identities = 30/106 (28%), Positives = 47/106 (44%), Gaps = 18/106 (16%)
Query: 157 AAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLP 216
A PG Q+ P K PAP PP+S PPKS +G + P P+
Sbjct: 949 AGQPGPHSQSGPGA-PMKQAPAPSQPPTSQGPPKS---TGQAPP-----------APAKS 993
Query: 217 TPPTREPKKVAVVRTPPK---SPSSAKSRLQTAPVPMPDLKNVKSK 259
P +E K A + PK +P+ ++ + P P+ D K++ ++
Sbjct: 994 IPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAE 1039
Score = 37.7 bits (86), Expect = 0.021
Identities = 51/218 (23%), Positives = 78/218 (35%), Gaps = 22/218 (10%)
Query: 64 SDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAGHVT 123
S+A T + ++G P + P + P ++ G G P +D ++
Sbjct: 182 SEASQEETTKKQKVVQKEQGKP-EGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSIS 240
Query: 124 --QARMVSKSKDGTGS--DDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTP--P 177
Q + GTG K+ R A+ P K QA+ R + P P
Sbjct: 241 SQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTK-QADIVRGESVKPSLP 299
Query: 178 APKTPP----SSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPP 233
+P PP + G+PP S PG P S L P ++P V+ P
Sbjct: 300 SPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPS---GLTKPLAQQP---GTVKPPV 353
Query: 234 KSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPG 271
+ P + K Q P+ K + GS + QPG
Sbjct: 354 QPPGTTKPPAQ----PLGPAKPPAQQTGSEKPSSEQPG 387
Score = 34.7 bits (78), Expect = 0.18
Identities = 48/213 (22%), Positives = 67/213 (31%), Gaps = 35/213 (16%)
Query: 122 VTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIP---AKTPP- 177
VT VSKS K A + P PP Q P AK PP
Sbjct: 666 VTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPE 725
Query: 178 -----------APKTPPSSGEPPKSGDR--------------SGYSSPGSPGTPGSR--S 210
P P + P + D+ S S+ P P S+ S
Sbjct: 726 ADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQS 785
Query: 211 RTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQP 270
+ TPP + PP + + P P D K + S+E+
Sbjct: 786 QAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSES----K 841
Query: 271 GGGKVQIINKKLDLSNVQSKCGSKDNIKHVPGG 303
G +V + KK + Q+K K + K +P G
Sbjct: 842 GQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKG 874
Score = 34.7 bits (78), Expect = 0.18
Identities = 49/205 (23%), Positives = 74/205 (36%), Gaps = 33/205 (16%)
Query: 35 QEGDTDAGLKESPLQTPTEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPH 94
Q + D+ K +P + P+ ++ D P T LV + A +P
Sbjct: 722 QPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSS----ATTKP- 776
Query: 95 TEIPEGTTAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATP 154
+IP +A TP L+ ++A S+S TG +K D K A P
Sbjct: 777 -DIPSSKVQSQAEEKTTPPLKTDSA-------KPSQSFPPTG---EKVSPFDSK---AIP 822
Query: 155 RGAAPP---GQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSR 211
R A+ G ++ ++ + P K EP K+ + P GS
Sbjct: 823 RPASDSKIISHPGPSSESKGQKQVDPVQKKE----EPKKAQTKMSPKPDAKPMPKGS--- 875
Query: 212 TPSLPTPPTREPKKVAVVRTPPKSP 236
PTPP P V TP +SP
Sbjct: 876 ----PTPPGPRPTAGQTVPTPQQSP 896
Score = 33.1 bits (74), Expect = 0.52
Identities = 58/223 (26%), Positives = 82/223 (36%), Gaps = 23/223 (10%)
Query: 45 ESPLQTPTEDGSEEPGSETSDAKS-------TPTAEDVTAPLVDEGAPGKQAAAQPHTEI 97
++ +QT ED E S K+ + T D T PL + Q A+ +
Sbjct: 3469 DTSVQTDDEDQDEWDMPTRSRRKARVGKYGDSMTEADKTKPLSKVSSIAVQTVAEISVQ- 3527
Query: 98 PEGTTAEEAGIGDTPSLEDEAAGHVTQARMVSK-SKDGTGSDDKKAKGADGKTKIATPRG 156
E G TPS+ V + +S K G AD T+
Sbjct: 3528 -----TEPVGTIRTPSIRARVDAKVEIIKHISAPEKTYKGGSLGCQTEADSDTQSPQYLS 3582
Query: 157 A-APPGQKGQANATRIPAKTP-PAPKTPPSSGEPPKSGDRSGYS--SPGSPGTPGSRSRT 212
A +PP K + I + A T + PPKS + YS SP SPG +
Sbjct: 3583 ATSPPKDKKRPTPLEIGYSSHLRADSTVQLAPSPPKS-PKVLYSPISPLSPGKALESAFV 3641
Query: 213 P-SLPTPPTREPKKVA---VVRTPPKSPSSAKSRLQTAPVPMP 251
P P P P+KV + + PP SP +AK ++ P P
Sbjct: 3642 PYEKPLPDDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPKP 3684
Score = 32.7 bits (73), Expect = 0.67
Identities = 25/105 (23%), Positives = 41/105 (39%), Gaps = 5/105 (4%)
Query: 171 IPAKTPPAPKTPP--SSGEPPKSGDRSGYSSPGSPGTPG---SRSRTPSLPTPPTREPKK 225
+P+ P KT P ++ KS + +SP P S++ P P P ++P
Sbjct: 653 VPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTL 712
Query: 226 VAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQP 270
K P A S + AP P + + + K ++ QP
Sbjct: 713 HGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQP 757
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 56.6 bits (135), Expect = 4e-08
Identities = 55/224 (24%), Positives = 82/224 (36%), Gaps = 13/224 (5%)
Query: 52 TEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQ-PHTEIP-EGTTAEEAGIG 109
T+ +++PG+ + T + PL P +Q ++ P +E P A+ G+G
Sbjct: 339 TKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVG 398
Query: 110 DTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPR---GAAPPGQKG-- 164
TP+ + A TQ K AK A G TK + G P Q G
Sbjct: 399 KTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAK-APGPTKTPVQQPGPGKIPAQQAGPG 457
Query: 165 -----QANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPP 219
Q T+ P++ P K PP P K + S+ PGS P P P
Sbjct: 458 KTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPA 517
Query: 220 TREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGST 263
P++ + P + P SAK Q P + + T
Sbjct: 518 KPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQT 561
Score = 53.9 bits (128), Expect = 3e-07
Identities = 65/243 (26%), Positives = 85/243 (34%), Gaps = 44/243 (18%)
Query: 47 PLQTPT--EDGSEEPGSETSD---AKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGT 101
P+Q PT + +++PG E S AK +T PL + K P T P
Sbjct: 305 PIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPP-- 362
Query: 102 TAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPG 161
A+ G P+ Q S + G GKT P A PP
Sbjct: 363 -AQPLGPAKPPA---------QQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPT 412
Query: 162 QK-------GQANATRIPAKTPPAPKTP---PSSGEPPKSGDRSGYSSPGSPGTPGSRSR 211
Q+ Q + PAK P KTP P G+ P G +S G S+
Sbjct: 413 QQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQ 472
Query: 212 TPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPG 271
P PP ++P + PP+ P SAK P P GST+ QPG
Sbjct: 473 LPGPAKPPPQQP---GPAKPPPQQPGSAKP-----PSQQP---------GSTKPPPQQPG 515
Query: 272 GGK 274
K
Sbjct: 516 PAK 518
Score = 43.9 bits (102), Expect = 3e-04
Identities = 65/252 (25%), Positives = 97/252 (38%), Gaps = 45/252 (17%)
Query: 47 PLQTPTED-GSEEPGSETSDAKS---------TPTAEDVTA--PLVDEGAPGKQAAAQPH 94
P + P + GSE+P SE K+ TP + A P G P K A QP
Sbjct: 368 PAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTP-KPLAQQPG 426
Query: 95 TEIPEG------TTAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGK 148
+ P T ++ G G P+ +A T A+ +K + K
Sbjct: 427 LQSPAKAPGPTKTPVQQPGPGKIPA--QQAGPGKTSAQQTGPTKPPSQLP------GPAK 478
Query: 149 TKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPK-SGDRSGYSSPGS--PGT 205
P A PP Q Q + + P++ P + K PP P K S + G + P S PG+
Sbjct: 479 PPPQQPGPAKPPPQ--QPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGS 536
Query: 206 --PGSRSRTPSLP-----TPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKS 258
P ++ +P+ P T P + ++ P SPS+ + Q P K +
Sbjct: 537 AKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLP------KTICP 590
Query: 259 KIGSTENLKHQP 270
+TE L H P
Sbjct: 591 LCNTTELLLHVP 602
Score = 40.4 bits (93), Expect = 0.003
Identities = 30/106 (28%), Positives = 47/106 (44%), Gaps = 18/106 (16%)
Query: 157 AAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLP 216
A PG Q+ P K PAP PP+S PPKS +G + P P+
Sbjct: 949 AGQPGPHSQSGPGA-PMKQAPAPSQPPTSQGPPKS---TGQAPP-----------APAKS 993
Query: 217 TPPTREPKKVAVVRTPPK---SPSSAKSRLQTAPVPMPDLKNVKSK 259
P +E K A + PK +P+ ++ + P P+ D K++ ++
Sbjct: 994 IPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAE 1039
Score = 37.7 bits (86), Expect = 0.021
Identities = 51/218 (23%), Positives = 78/218 (35%), Gaps = 22/218 (10%)
Query: 64 SDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAGHVT 123
S+A T + ++G P + P + P ++ G G P +D ++
Sbjct: 182 SEASQEETTKKQKVVQKEQGKP-EGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSIS 240
Query: 124 --QARMVSKSKDGTGS--DDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTP--P 177
Q + GTG K+ R A+ P K QA+ R + P P
Sbjct: 241 SQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTK-QADIVRGESVKPSLP 299
Query: 178 APKTPP----SSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPP 233
+P PP + G+PP S PG P S L P ++P V+ P
Sbjct: 300 SPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPS---GLTKPLAQQP---GTVKPPV 353
Query: 234 KSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPG 271
+ P + K Q P+ K + GS + QPG
Sbjct: 354 QPPGTTKPPAQ----PLGPAKPPAQQTGSEKPSSEQPG 387
Score = 34.7 bits (78), Expect = 0.18
Identities = 48/213 (22%), Positives = 67/213 (31%), Gaps = 35/213 (16%)
Query: 122 VTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIP---AKTPP- 177
VT VSKS K A + P PP Q P AK PP
Sbjct: 666 VTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPE 725
Query: 178 -----------APKTPPSSGEPPKSGDR--------------SGYSSPGSPGTPGSR--S 210
P P + P + D+ S S+ P P S+ S
Sbjct: 726 ADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQS 785
Query: 211 RTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQP 270
+ TPP + PP + + P P D K + S+E+
Sbjct: 786 QAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSES----K 841
Query: 271 GGGKVQIINKKLDLSNVQSKCGSKDNIKHVPGG 303
G +V + KK + Q+K K + K +P G
Sbjct: 842 GQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKG 874
Score = 34.7 bits (78), Expect = 0.18
Identities = 49/205 (23%), Positives = 74/205 (36%), Gaps = 33/205 (16%)
Query: 35 QEGDTDAGLKESPLQTPTEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPH 94
Q + D+ K +P + P+ ++ D P T LV + A +P
Sbjct: 722 QPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSS----ATTKP- 776
Query: 95 TEIPEGTTAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATP 154
+IP +A TP L+ ++A S+S TG +K D K A P
Sbjct: 777 -DIPSSKVQSQAEEKTTPPLKTDSA-------KPSQSFPPTG---EKVSPFDSK---AIP 822
Query: 155 RGAAPP---GQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSR 211
R A+ G ++ ++ + P K EP K+ + P GS
Sbjct: 823 RPASDSKIISHPGPSSESKGQKQVDPVQKKE----EPKKAQTKMSPKPDAKPMPKGS--- 875
Query: 212 TPSLPTPPTREPKKVAVVRTPPKSP 236
PTPP P V TP +SP
Sbjct: 876 ----PTPPGPRPTAGQTVPTPQQSP 896
Score = 33.1 bits (74), Expect = 0.52
Identities = 58/223 (26%), Positives = 82/223 (36%), Gaps = 23/223 (10%)
Query: 45 ESPLQTPTEDGSEEPGSETSDAKS-------TPTAEDVTAPLVDEGAPGKQAAAQPHTEI 97
++ +QT ED E S K+ + T D T PL + Q A+ +
Sbjct: 3469 DTSVQTDDEDQDEWDMPTRSRRKARVGKYGDSMTEADKTKPLSKVSSIAVQTVAEISVQ- 3527
Query: 98 PEGTTAEEAGIGDTPSLEDEAAGHVTQARMVSK-SKDGTGSDDKKAKGADGKTKIATPRG 156
E G TPS+ V + +S K G AD T+
Sbjct: 3528 -----TEPVGTIRTPSIRARVDAKVEIIKHISAPEKTYKGGSLGCQTEADSDTQSPQYLS 3582
Query: 157 A-APPGQKGQANATRIPAKTP-PAPKTPPSSGEPPKSGDRSGYS--SPGSPGTPGSRSRT 212
A +PP K + I + A T + PPKS + YS SP SPG +
Sbjct: 3583 ATSPPKDKKRPTPLEIGYSSHLRADSTVQLAPSPPKS-PKVLYSPISPLSPGKALESAFV 3641
Query: 213 P-SLPTPPTREPKKVA---VVRTPPKSPSSAKSRLQTAPVPMP 251
P P P P+KV + + PP SP +AK ++ P P
Sbjct: 3642 PYEKPLPDDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPKP 3684
Score = 32.7 bits (73), Expect = 0.67
Identities = 25/105 (23%), Positives = 41/105 (39%), Gaps = 5/105 (4%)
Query: 171 IPAKTPPAPKTPP--SSGEPPKSGDRSGYSSPGSPGTPG---SRSRTPSLPTPPTREPKK 225
+P+ P KT P ++ KS + +SP P S++ P P P ++P
Sbjct: 653 VPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTL 712
Query: 226 VAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQP 270
K P A S + AP P + + + K ++ QP
Sbjct: 713 HGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQP 757
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 56.2 bits (134), Expect = 6e-08
Identities = 55/222 (24%), Positives = 80/222 (36%), Gaps = 20/222 (9%)
Query: 44 KESPLQTPTEDGSEEPGSET-SDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHT-EIPEGT 101
KE TP E S P T + KS PT AP + AP P T + P T
Sbjct: 214 KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT 273
Query: 102 TAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPG 161
T +E P+ E A T++ + + + K A + TP+ P
Sbjct: 274 TPKEPA----PTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTT 329
Query: 162 QKGQANATRIPAKTPPAPKTPPSSGEP-PKSGDRSGYSSPGSPGTPGSRSRTPSLPTPP- 219
K A T+ PA T P P + +P P + ++P P ++ +P+ P P
Sbjct: 330 PKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPA 389
Query: 220 ----------TREPKKVAVVRTP--PKSPSSAKSRLQTAPVP 249
T+EP P PK PS ++ P
Sbjct: 390 PTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTP 431
Score = 48.9 bits (115), Expect = 9e-06
Identities = 58/230 (25%), Positives = 83/230 (36%), Gaps = 24/230 (10%)
Query: 57 EEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHT-EIPEGTTAEEAG----IGDT 111
E+P T + + T E+ T +E AP AA P+T + P TT +E
Sbjct: 504 EKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPA 563
Query: 112 PSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGAD--------------GKTKIATPRGA 157
P+ E A + + K+ + KK + K TP+G
Sbjct: 564 PTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGT 623
Query: 158 APPGQKGQANAT-RIPAKTPPAPKTPPSSGEP-PKSGDRSGYSSPGSPGTPGSRSRTPSL 215
AP K A T + PA T P P + EP P + + T G S T
Sbjct: 624 APTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDK 683
Query: 216 PTPPTREPKKVAVVRTPPKSPSSAKSRLQTAP-VPMPDLKNVKSKIGSTE 264
P P T PK+ A +P++ K T P P P V + + E
Sbjct: 684 PAPTT--PKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKE 731
Score = 47.0 bits (110), Expect = 3e-05
Identities = 47/204 (23%), Positives = 77/204 (37%), Gaps = 21/204 (10%)
Query: 50 TPTEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPH------TEIPEGTTA 103
T + S + +T+ AK T + E +A + AP + A+P T+ P TT
Sbjct: 157 TTNKQTSTDGKEKTTSAKETQSIEKTSAK---DLAPTSKVLAKPTPKAETTTKGPALTTP 213
Query: 104 EEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQK 163
+E TP+ E A + K+ T + K A + T + A ++
Sbjct: 214 KEP----TPTTPKEPAS--------TTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKE 261
Query: 164 GQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREP 223
T+ PA T P P ++ EP + +S ++P P + P+ P P
Sbjct: 262 PAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTT 321
Query: 224 KKVAVVRTPPKSPSSAKSRLQTAP 247
K TP + + K T P
Sbjct: 322 PKEPTPTTPKEPAPTTKEPAPTTP 345
Score = 45.8 bits (107), Expect = 8e-05
Identities = 55/202 (27%), Positives = 77/202 (38%), Gaps = 26/202 (12%)
Query: 44 KESPLQTPTEDG---SEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEG 100
KE TP E ++EP T+ KS PT AP P K A P P
Sbjct: 268 KEPAPTTPKEPAPTTTKEPAPTTT--KSAPTTPKEPAPTT----PKKPAPTTPKEPAP-- 319
Query: 101 TTAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPP 160
TT +E TP+ E A + + + + K A + TP+ AP
Sbjct: 320 TTPKEP----TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPT 375
Query: 161 GQKGQANATRIPAKTPPAPKT----PPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLP 216
K + T PAP T P ++ EP + +S ++P P ++ P+ P
Sbjct: 376 TTKEPSPTT----PKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTP 431
Query: 217 TPPT-REPKKVAVVRTPPKSPS 237
P PKK A T PK P+
Sbjct: 432 KEPAPTTPKKPA--PTTPKEPA 451
Score = 44.7 bits (104), Expect = 2e-04
Identities = 42/186 (22%), Positives = 66/186 (35%), Gaps = 8/186 (4%)
Query: 66 AKSTPTAEDVTA--PLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAGHVT 123
AK TP AE T L P +P + P+ T I P+ E A T
Sbjct: 195 AKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTT--IKSAPTTPKEPAPTTT 252
Query: 124 QARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPP 183
++ + + + + A + T + AP K + PA T P P
Sbjct: 253 KSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPT 312
Query: 184 SSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRL 243
+ EP + + +P +P P ++ P+ TP +EP A + P +P
Sbjct: 313 TPKEPAPTTPKE--PTPTTPKEPAPTTKEPAPTTP--KEPAPTAPKKPAPTTPKEPAPTT 368
Query: 244 QTAPVP 249
P P
Sbjct: 369 PKEPAP 374
Score = 41.6 bits (96), Expect = 0.001
Identities = 65/260 (25%), Positives = 92/260 (35%), Gaps = 45/260 (17%)
Query: 36 EGDTDAGLKESPLQTPTEDG--------SEEPGSETSDAKSTPTAEDVTAPLVDEGAPGK 87
+G LKE TP + ++EP S T D K PT TAP + P
Sbjct: 576 KGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCD-KPAPTTPKGTAPTTPK-EPAP 633
Query: 88 QAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADG 147
+P P+GT + + + A +K T SD K A
Sbjct: 634 TTPKEPAPTTPKGTAPTT--LKEPAPTTPKKPAPKELAPTTTKGPTSTTSD-KPAPTTPK 690
Query: 148 KTKIATPRGAAPPGQKGQANATRIPAKTPPAPK---------------------TPPSSG 186
+T TP+ AP K A T P PP TP S
Sbjct: 691 ETAPTTPKEPAPTTPKKPAPTT--PETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSA 748
Query: 187 EP-PKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAV--VRTPPKSPSSAKSRL 243
EP PK+ + +SP PG P +++ + P T K +RT P++ ++A
Sbjct: 749 EPTPKALE----NSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPK-- 802
Query: 244 QTAPVPMPDLKNVKSKIGST 263
T K +SKI +T
Sbjct: 803 MTKETATTTEKTTESKITAT 822
Score = 40.8 bits (94), Expect = 0.002
Identities = 48/199 (24%), Positives = 73/199 (36%), Gaps = 33/199 (16%)
Query: 59 PGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEA 118
P S+TS S ++ T + KQ + T+ E TT+ + +T S+E
Sbjct: 132 PNSDTSKETSLTVNKETTVETKETTTTNKQTS----TDGKEKTTSAK----ETQSIEK-- 181
Query: 119 AGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPA 178
T A+ ++ + KA+ + TP+ P K PA T P
Sbjct: 182 ----TSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKE-------PASTTPK 230
Query: 179 PKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTRE------PKKVAVVRTP 232
TP + P + +P T S TP P P T + PK+ A T
Sbjct: 231 EPTPTTIKSAPTT------PKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTK 284
Query: 233 PKSPSSAKSRLQTAPVPMP 251
+P++ KS T P P
Sbjct: 285 EPAPTTTKSAPTTPKEPAP 303
Score = 33.9 bits (76), Expect = 0.30
Identities = 57/272 (20%), Positives = 96/272 (35%), Gaps = 47/272 (17%)
Query: 30 TMHQDQEGDTDAGLKESPLQTPTEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQA 89
T+H+ + T L P E+ +EPG T+ TP A T P + A K
Sbjct: 734 TIHKSPDESTPE-LSAEPTPKALENSPKEPGVPTT---KTPAA---TKPEMTTTAKDKTT 786
Query: 90 AAQPHTEIPEGTTAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGS---DDKKAKGAD 146
T PE TTA +T + ++ T++++ + + T + D K
Sbjct: 787 ERDLRTT-PETTTAAPKMTKETATTTEKT----TESKITATTTQVTSTTTQDTTPFKITT 841
Query: 147 GKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTP 206
KT P+ T+ T P + +P DR+
Sbjct: 842 LKTTTLAPK----------VTTTKKTITTTEIMNKPEETAKPK---DRA----------T 878
Query: 207 GSRSRTPSLPTPPTREPKKVAVVRTP--------PKSPSSAKSRLQTAPVPMPDLKNVKS 258
S++ TP P PT+ PKK + P PK+ + + T P P + ++
Sbjct: 879 NSKATTPK-PQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEA 937
Query: 259 KIGSTENLKHQPGGGKVQIINKKLDLSNVQSK 290
+ +T P V++ K D + +
Sbjct: 938 MLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGE 969
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 56.2 bits (134), Expect = 6e-08
Identities = 55/222 (24%), Positives = 80/222 (36%), Gaps = 20/222 (9%)
Query: 44 KESPLQTPTEDGSEEPGSET-SDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHT-EIPEGT 101
KE TP E S P T + KS PT AP + AP P T + P T
Sbjct: 255 KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT 314
Query: 102 TAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPG 161
T +E P+ E A T++ + + + K A + TP+ P
Sbjct: 315 TPKEPA----PTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTT 370
Query: 162 QKGQANATRIPAKTPPAPKTPPSSGEP-PKSGDRSGYSSPGSPGTPGSRSRTPSLPTPP- 219
K A T+ PA T P P + +P P + ++P P ++ +P+ P P
Sbjct: 371 PKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPA 430
Query: 220 ----------TREPKKVAVVRTP--PKSPSSAKSRLQTAPVP 249
T+EP P PK PS ++ P
Sbjct: 431 PTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTP 472
Score = 48.9 bits (115), Expect = 9e-06
Identities = 58/230 (25%), Positives = 83/230 (36%), Gaps = 24/230 (10%)
Query: 57 EEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHT-EIPEGTTAEEAG----IGDT 111
E+P T + + T E+ T +E AP AA P+T + P TT +E
Sbjct: 545 EKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPA 604
Query: 112 PSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGAD--------------GKTKIATPRGA 157
P+ E A + + K+ + KK + K TP+G
Sbjct: 605 PTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGT 664
Query: 158 APPGQKGQANAT-RIPAKTPPAPKTPPSSGEP-PKSGDRSGYSSPGSPGTPGSRSRTPSL 215
AP K A T + PA T P P + EP P + + T G S T
Sbjct: 665 APTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDK 724
Query: 216 PTPPTREPKKVAVVRTPPKSPSSAKSRLQTAP-VPMPDLKNVKSKIGSTE 264
P P T PK+ A +P++ K T P P P V + + E
Sbjct: 725 PAPTT--PKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKE 772
Score = 47.0 bits (110), Expect = 3e-05
Identities = 47/204 (23%), Positives = 77/204 (37%), Gaps = 21/204 (10%)
Query: 50 TPTEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPH------TEIPEGTTA 103
T + S + +T+ AK T + E +A + AP + A+P T+ P TT
Sbjct: 198 TTNKQTSTDGKEKTTSAKETQSIEKTSAK---DLAPTSKVLAKPTPKAETTTKGPALTTP 254
Query: 104 EEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQK 163
+E TP+ E A + K+ T + K A + T + A ++
Sbjct: 255 KEP----TPTTPKEPAS--------TTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKE 302
Query: 164 GQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREP 223
T+ PA T P P ++ EP + +S ++P P + P+ P P
Sbjct: 303 PAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTT 362
Query: 224 KKVAVVRTPPKSPSSAKSRLQTAP 247
K TP + + K T P
Sbjct: 363 PKEPTPTTPKEPAPTTKEPAPTTP 386
Score = 45.8 bits (107), Expect = 8e-05
Identities = 55/202 (27%), Positives = 77/202 (38%), Gaps = 26/202 (12%)
Query: 44 KESPLQTPTEDG---SEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEG 100
KE TP E ++EP T+ KS PT AP P K A P P
Sbjct: 309 KEPAPTTPKEPAPTTTKEPAPTTT--KSAPTTPKEPAPTT----PKKPAPTTPKEPAP-- 360
Query: 101 TTAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPP 160
TT +E TP+ E A + + + + K A + TP+ AP
Sbjct: 361 TTPKEP----TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPT 416
Query: 161 GQKGQANATRIPAKTPPAPKT----PPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLP 216
K + T PAP T P ++ EP + +S ++P P ++ P+ P
Sbjct: 417 TTKEPSPTT----PKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTP 472
Query: 217 TPPT-REPKKVAVVRTPPKSPS 237
P PKK A T PK P+
Sbjct: 473 KEPAPTTPKKPA--PTTPKEPA 492
Score = 44.7 bits (104), Expect = 2e-04
Identities = 42/186 (22%), Positives = 66/186 (35%), Gaps = 8/186 (4%)
Query: 66 AKSTPTAEDVTA--PLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAGHVT 123
AK TP AE T L P +P + P+ T I P+ E A T
Sbjct: 236 AKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTT--IKSAPTTPKEPAPTTT 293
Query: 124 QARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPP 183
++ + + + + A + T + AP K + PA T P P
Sbjct: 294 KSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPT 353
Query: 184 SSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRL 243
+ EP + + +P +P P ++ P+ TP +EP A + P +P
Sbjct: 354 TPKEPAPTTPKE--PTPTTPKEPAPTTKEPAPTTP--KEPAPTAPKKPAPTTPKEPAPTT 409
Query: 244 QTAPVP 249
P P
Sbjct: 410 PKEPAP 415
Score = 41.6 bits (96), Expect = 0.001
Identities = 65/260 (25%), Positives = 92/260 (35%), Gaps = 45/260 (17%)
Query: 36 EGDTDAGLKESPLQTPTEDG--------SEEPGSETSDAKSTPTAEDVTAPLVDEGAPGK 87
+G LKE TP + ++EP S T D K PT TAP + P
Sbjct: 617 KGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCD-KPAPTTPKGTAPTTPK-EPAP 674
Query: 88 QAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADG 147
+P P+GT + + + A +K T SD K A
Sbjct: 675 TTPKEPAPTTPKGTAPTT--LKEPAPTTPKKPAPKELAPTTTKGPTSTTSD-KPAPTTPK 731
Query: 148 KTKIATPRGAAPPGQKGQANATRIPAKTPPAPK---------------------TPPSSG 186
+T TP+ AP K A T P PP TP S
Sbjct: 732 ETAPTTPKEPAPTTPKKPAPTT--PETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSA 789
Query: 187 EP-PKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAV--VRTPPKSPSSAKSRL 243
EP PK+ + +SP PG P +++ + P T K +RT P++ ++A
Sbjct: 790 EPTPKALE----NSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPK-- 843
Query: 244 QTAPVPMPDLKNVKSKIGST 263
T K +SKI +T
Sbjct: 844 MTKETATTTEKTTESKITAT 863
Score = 40.8 bits (94), Expect = 0.002
Identities = 48/199 (24%), Positives = 73/199 (36%), Gaps = 33/199 (16%)
Query: 59 PGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEA 118
P S+TS S ++ T + KQ + T+ E TT+ + +T S+E
Sbjct: 173 PNSDTSKETSLTVNKETTVETKETTTTNKQTS----TDGKEKTTSAK----ETQSIEK-- 222
Query: 119 AGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPA 178
T A+ ++ + KA+ + TP+ P K PA T P
Sbjct: 223 ----TSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKE-------PASTTPK 271
Query: 179 PKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTRE------PKKVAVVRTP 232
TP + P + +P T S TP P P T + PK+ A T
Sbjct: 272 EPTPTTIKSAPTT------PKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTK 325
Query: 233 PKSPSSAKSRLQTAPVPMP 251
+P++ KS T P P
Sbjct: 326 EPAPTTTKSAPTTPKEPAP 344
Score = 33.9 bits (76), Expect = 0.30
Identities = 57/272 (20%), Positives = 96/272 (35%), Gaps = 47/272 (17%)
Query: 30 TMHQDQEGDTDAGLKESPLQTPTEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQA 89
T+H+ + T L P E+ +EPG T+ TP A T P + A K
Sbjct: 775 TIHKSPDESTPE-LSAEPTPKALENSPKEPGVPTT---KTPAA---TKPEMTTTAKDKTT 827
Query: 90 AAQPHTEIPEGTTAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGS---DDKKAKGAD 146
T PE TTA +T + ++ T++++ + + T + D K
Sbjct: 828 ERDLRTT-PETTTAAPKMTKETATTTEKT----TESKITATTTQVTSTTTQDTTPFKITT 882
Query: 147 GKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTP 206
KT P+ T+ T P + +P DR+
Sbjct: 883 LKTTTLAPK----------VTTTKKTITTTEIMNKPEETAKPK---DRA----------T 919
Query: 207 GSRSRTPSLPTPPTREPKKVAVVRTP--------PKSPSSAKSRLQTAPVPMPDLKNVKS 258
S++ TP P PT+ PKK + P PK+ + + T P P + ++
Sbjct: 920 NSKATTPK-PQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEA 978
Query: 259 KIGSTENLKHQPGGGKVQIINKKLDLSNVQSK 290
+ +T P V++ K D + +
Sbjct: 979 MLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGE 1010
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 56.2 bits (134), Expect = 6e-08
Identities = 55/222 (24%), Positives = 80/222 (36%), Gaps = 20/222 (9%)
Query: 44 KESPLQTPTEDGSEEPGSET-SDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHT-EIPEGT 101
KE TP E S P T + KS PT AP + AP P T + P T
Sbjct: 307 KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT 366
Query: 102 TAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPG 161
T +E P+ E A T++ + + + K A + TP+ P
Sbjct: 367 TPKEPA----PTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTT 422
Query: 162 QKGQANATRIPAKTPPAPKTPPSSGEP-PKSGDRSGYSSPGSPGTPGSRSRTPSLPTPP- 219
K A T+ PA T P P + +P P + ++P P ++ +P+ P P
Sbjct: 423 PKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPA 482
Query: 220 ----------TREPKKVAVVRTP--PKSPSSAKSRLQTAPVP 249
T+EP P PK PS ++ P
Sbjct: 483 PTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTP 524
Score = 48.9 bits (115), Expect = 9e-06
Identities = 58/230 (25%), Positives = 83/230 (36%), Gaps = 24/230 (10%)
Query: 57 EEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHT-EIPEGTTAEEAG----IGDT 111
E+P T + + T E+ T +E AP AA P+T + P TT +E
Sbjct: 597 EKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPA 656
Query: 112 PSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGAD--------------GKTKIATPRGA 157
P+ E A + + K+ + KK + K TP+G
Sbjct: 657 PTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGT 716
Query: 158 APPGQKGQANAT-RIPAKTPPAPKTPPSSGEP-PKSGDRSGYSSPGSPGTPGSRSRTPSL 215
AP K A T + PA T P P + EP P + + T G S T
Sbjct: 717 APTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDK 776
Query: 216 PTPPTREPKKVAVVRTPPKSPSSAKSRLQTAP-VPMPDLKNVKSKIGSTE 264
P P T PK+ A +P++ K T P P P V + + E
Sbjct: 777 PAPTT--PKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKE 824
Score = 47.0 bits (110), Expect = 3e-05
Identities = 47/204 (23%), Positives = 77/204 (37%), Gaps = 21/204 (10%)
Query: 50 TPTEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPH------TEIPEGTTA 103
T + S + +T+ AK T + E +A + AP + A+P T+ P TT
Sbjct: 250 TTNKQTSTDGKEKTTSAKETQSIEKTSAK---DLAPTSKVLAKPTPKAETTTKGPALTTP 306
Query: 104 EEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQK 163
+E TP+ E A + K+ T + K A + T + A ++
Sbjct: 307 KEP----TPTTPKEPAS--------TTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKE 354
Query: 164 GQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREP 223
T+ PA T P P ++ EP + +S ++P P + P+ P P
Sbjct: 355 PAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTT 414
Query: 224 KKVAVVRTPPKSPSSAKSRLQTAP 247
K TP + + K T P
Sbjct: 415 PKEPTPTTPKEPAPTTKEPAPTTP 438
Score = 45.8 bits (107), Expect = 8e-05
Identities = 55/202 (27%), Positives = 77/202 (38%), Gaps = 26/202 (12%)
Query: 44 KESPLQTPTEDG---SEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEG 100
KE TP E ++EP T+ KS PT AP P K A P P
Sbjct: 361 KEPAPTTPKEPAPTTTKEPAPTTT--KSAPTTPKEPAPTT----PKKPAPTTPKEPAP-- 412
Query: 101 TTAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPP 160
TT +E TP+ E A + + + + K A + TP+ AP
Sbjct: 413 TTPKEP----TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPT 468
Query: 161 GQKGQANATRIPAKTPPAPKT----PPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLP 216
K + T PAP T P ++ EP + +S ++P P ++ P+ P
Sbjct: 469 TTKEPSPTT----PKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTP 524
Query: 217 TPPT-REPKKVAVVRTPPKSPS 237
P PKK A T PK P+
Sbjct: 525 KEPAPTTPKKPA--PTTPKEPA 544
Score = 44.7 bits (104), Expect = 2e-04
Identities = 42/186 (22%), Positives = 66/186 (35%), Gaps = 8/186 (4%)
Query: 66 AKSTPTAEDVTA--PLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAGHVT 123
AK TP AE T L P +P + P+ T I P+ E A T
Sbjct: 288 AKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTT--IKSAPTTPKEPAPTTT 345
Query: 124 QARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPP 183
++ + + + + A + T + AP K + PA T P P
Sbjct: 346 KSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPT 405
Query: 184 SSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRL 243
+ EP + + +P +P P ++ P+ TP +EP A + P +P
Sbjct: 406 TPKEPAPTTPKE--PTPTTPKEPAPTTKEPAPTTP--KEPAPTAPKKPAPTTPKEPAPTT 461
Query: 244 QTAPVP 249
P P
Sbjct: 462 PKEPAP 467
Score = 41.6 bits (96), Expect = 0.001
Identities = 65/260 (25%), Positives = 92/260 (35%), Gaps = 45/260 (17%)
Query: 36 EGDTDAGLKESPLQTPTEDG--------SEEPGSETSDAKSTPTAEDVTAPLVDEGAPGK 87
+G LKE TP + ++EP S T D K PT TAP + P
Sbjct: 669 KGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCD-KPAPTTPKGTAPTTPK-EPAP 726
Query: 88 QAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADG 147
+P P+GT + + + A +K T SD K A
Sbjct: 727 TTPKEPAPTTPKGTAPTT--LKEPAPTTPKKPAPKELAPTTTKGPTSTTSD-KPAPTTPK 783
Query: 148 KTKIATPRGAAPPGQKGQANATRIPAKTPPAPK---------------------TPPSSG 186
+T TP+ AP K A T P PP TP S
Sbjct: 784 ETAPTTPKEPAPTTPKKPAPTT--PETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSA 841
Query: 187 EP-PKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAV--VRTPPKSPSSAKSRL 243
EP PK+ + +SP PG P +++ + P T K +RT P++ ++A
Sbjct: 842 EPTPKALE----NSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPK-- 895
Query: 244 QTAPVPMPDLKNVKSKIGST 263
T K +SKI +T
Sbjct: 896 MTKETATTTEKTTESKITAT 915
Score = 40.8 bits (94), Expect = 0.002
Identities = 48/199 (24%), Positives = 73/199 (36%), Gaps = 33/199 (16%)
Query: 59 PGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEA 118
P S+TS S ++ T + KQ + T+ E TT+ + +T S+E
Sbjct: 225 PNSDTSKETSLTVNKETTVETKETTTTNKQTS----TDGKEKTTSAK----ETQSIEK-- 274
Query: 119 AGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPA 178
T A+ ++ + KA+ + TP+ P K PA T P
Sbjct: 275 ----TSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKE-------PASTTPK 323
Query: 179 PKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTRE------PKKVAVVRTP 232
TP + P + +P T S TP P P T + PK+ A T
Sbjct: 324 EPTPTTIKSAPTT------PKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTK 377
Query: 233 PKSPSSAKSRLQTAPVPMP 251
+P++ KS T P P
Sbjct: 378 EPAPTTTKSAPTTPKEPAP 396
Score = 33.9 bits (76), Expect = 0.30
Identities = 57/272 (20%), Positives = 96/272 (35%), Gaps = 47/272 (17%)
Query: 30 TMHQDQEGDTDAGLKESPLQTPTEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQA 89
T+H+ + T L P E+ +EPG T+ TP A T P + A K
Sbjct: 827 TIHKSPDESTPE-LSAEPTPKALENSPKEPGVPTT---KTPAA---TKPEMTTTAKDKTT 879
Query: 90 AAQPHTEIPEGTTAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGS---DDKKAKGAD 146
T PE TTA +T + ++ T++++ + + T + D K
Sbjct: 880 ERDLRTT-PETTTAAPKMTKETATTTEKT----TESKITATTTQVTSTTTQDTTPFKITT 934
Query: 147 GKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTP 206
KT P+ T+ T P + +P DR+
Sbjct: 935 LKTTTLAPK----------VTTTKKTITTTEIMNKPEETAKPK---DRA----------T 971
Query: 207 GSRSRTPSLPTPPTREPKKVAVVRTP--------PKSPSSAKSRLQTAPVPMPDLKNVKS 258
S++ TP P PT+ PKK + P PK+ + + T P P + ++
Sbjct: 972 NSKATTPK-PQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEA 1030
Query: 259 KIGSTENLKHQPGGGKVQIINKKLDLSNVQSK 290
+ +T P V++ K D + +
Sbjct: 1031 MLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGE 1062
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 56.2 bits (134), Expect = 6e-08
Identities = 55/222 (24%), Positives = 80/222 (36%), Gaps = 20/222 (9%)
Query: 44 KESPLQTPTEDGSEEPGSET-SDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHT-EIPEGT 101
KE TP E S P T + KS PT AP + AP P T + P T
Sbjct: 348 KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT 407
Query: 102 TAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPG 161
T +E P+ E A T++ + + + K A + TP+ P
Sbjct: 408 TPKEPA----PTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTT 463
Query: 162 QKGQANATRIPAKTPPAPKTPPSSGEP-PKSGDRSGYSSPGSPGTPGSRSRTPSLPTPP- 219
K A T+ PA T P P + +P P + ++P P ++ +P+ P P
Sbjct: 464 PKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPA 523
Query: 220 ----------TREPKKVAVVRTP--PKSPSSAKSRLQTAPVP 249
T+EP P PK PS ++ P
Sbjct: 524 PTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTP 565
Score = 48.9 bits (115), Expect = 9e-06
Identities = 58/230 (25%), Positives = 83/230 (36%), Gaps = 24/230 (10%)
Query: 57 EEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHT-EIPEGTTAEEAG----IGDT 111
E+P T + + T E+ T +E AP AA P+T + P TT +E
Sbjct: 638 EKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPA 697
Query: 112 PSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGAD--------------GKTKIATPRGA 157
P+ E A + + K+ + KK + K TP+G
Sbjct: 698 PTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGT 757
Query: 158 APPGQKGQANAT-RIPAKTPPAPKTPPSSGEP-PKSGDRSGYSSPGSPGTPGSRSRTPSL 215
AP K A T + PA T P P + EP P + + T G S T
Sbjct: 758 APTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDK 817
Query: 216 PTPPTREPKKVAVVRTPPKSPSSAKSRLQTAP-VPMPDLKNVKSKIGSTE 264
P P T PK+ A +P++ K T P P P V + + E
Sbjct: 818 PAPTT--PKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKE 865
Score = 47.0 bits (110), Expect = 3e-05
Identities = 47/204 (23%), Positives = 77/204 (37%), Gaps = 21/204 (10%)
Query: 50 TPTEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPH------TEIPEGTTA 103
T + S + +T+ AK T + E +A + AP + A+P T+ P TT
Sbjct: 291 TTNKQTSTDGKEKTTSAKETQSIEKTSAK---DLAPTSKVLAKPTPKAETTTKGPALTTP 347
Query: 104 EEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQK 163
+E TP+ E A + K+ T + K A + T + A ++
Sbjct: 348 KEP----TPTTPKEPAS--------TTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKE 395
Query: 164 GQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREP 223
T+ PA T P P ++ EP + +S ++P P + P+ P P
Sbjct: 396 PAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTT 455
Query: 224 KKVAVVRTPPKSPSSAKSRLQTAP 247
K TP + + K T P
Sbjct: 456 PKEPTPTTPKEPAPTTKEPAPTTP 479
Score = 45.8 bits (107), Expect = 8e-05
Identities = 55/202 (27%), Positives = 77/202 (38%), Gaps = 26/202 (12%)
Query: 44 KESPLQTPTEDG---SEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEG 100
KE TP E ++EP T+ KS PT AP P K A P P
Sbjct: 402 KEPAPTTPKEPAPTTTKEPAPTTT--KSAPTTPKEPAPTT----PKKPAPTTPKEPAP-- 453
Query: 101 TTAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPP 160
TT +E TP+ E A + + + + K A + TP+ AP
Sbjct: 454 TTPKEP----TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPT 509
Query: 161 GQKGQANATRIPAKTPPAPKT----PPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLP 216
K + T PAP T P ++ EP + +S ++P P ++ P+ P
Sbjct: 510 TTKEPSPTT----PKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTP 565
Query: 217 TPPT-REPKKVAVVRTPPKSPS 237
P PKK A T PK P+
Sbjct: 566 KEPAPTTPKKPA--PTTPKEPA 585
Score = 44.7 bits (104), Expect = 2e-04
Identities = 42/186 (22%), Positives = 66/186 (35%), Gaps = 8/186 (4%)
Query: 66 AKSTPTAEDVTA--PLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAGHVT 123
AK TP AE T L P +P + P+ T I P+ E A T
Sbjct: 329 AKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTT--IKSAPTTPKEPAPTTT 386
Query: 124 QARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPP 183
++ + + + + A + T + AP K + PA T P P
Sbjct: 387 KSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPT 446
Query: 184 SSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRL 243
+ EP + + +P +P P ++ P+ TP +EP A + P +P
Sbjct: 447 TPKEPAPTTPKE--PTPTTPKEPAPTTKEPAPTTP--KEPAPTAPKKPAPTTPKEPAPTT 502
Query: 244 QTAPVP 249
P P
Sbjct: 503 PKEPAP 508
Score = 41.6 bits (96), Expect = 0.001
Identities = 65/260 (25%), Positives = 92/260 (35%), Gaps = 45/260 (17%)
Query: 36 EGDTDAGLKESPLQTPTEDG--------SEEPGSETSDAKSTPTAEDVTAPLVDEGAPGK 87
+G LKE TP + ++EP S T D K PT TAP + P
Sbjct: 710 KGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCD-KPAPTTPKGTAPTTPK-EPAP 767
Query: 88 QAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADG 147
+P P+GT + + + A +K T SD K A
Sbjct: 768 TTPKEPAPTTPKGTAPTT--LKEPAPTTPKKPAPKELAPTTTKGPTSTTSD-KPAPTTPK 824
Query: 148 KTKIATPRGAAPPGQKGQANATRIPAKTPPAPK---------------------TPPSSG 186
+T TP+ AP K A T P PP TP S
Sbjct: 825 ETAPTTPKEPAPTTPKKPAPTT--PETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSA 882
Query: 187 EP-PKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAV--VRTPPKSPSSAKSRL 243
EP PK+ + +SP PG P +++ + P T K +RT P++ ++A
Sbjct: 883 EPTPKALE----NSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPK-- 936
Query: 244 QTAPVPMPDLKNVKSKIGST 263
T K +SKI +T
Sbjct: 937 MTKETATTTEKTTESKITAT 956
Score = 40.8 bits (94), Expect = 0.002
Identities = 48/199 (24%), Positives = 73/199 (36%), Gaps = 33/199 (16%)
Query: 59 PGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEA 118
P S+TS S ++ T + KQ + T+ E TT+ + +T S+E
Sbjct: 266 PNSDTSKETSLTVNKETTVETKETTTTNKQTS----TDGKEKTTSAK----ETQSIEK-- 315
Query: 119 AGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPA 178
T A+ ++ + KA+ + TP+ P K PA T P
Sbjct: 316 ----TSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKE-------PASTTPK 364
Query: 179 PKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTRE------PKKVAVVRTP 232
TP + P + +P T S TP P P T + PK+ A T
Sbjct: 365 EPTPTTIKSAPTT------PKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTK 418
Query: 233 PKSPSSAKSRLQTAPVPMP 251
+P++ KS T P P
Sbjct: 419 EPAPTTTKSAPTTPKEPAP 437
Score = 33.9 bits (76), Expect = 0.30
Identities = 57/272 (20%), Positives = 96/272 (35%), Gaps = 47/272 (17%)
Query: 30 TMHQDQEGDTDAGLKESPLQTPTEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQA 89
T+H+ + T L P E+ +EPG T+ TP A T P + A K
Sbjct: 868 TIHKSPDESTPE-LSAEPTPKALENSPKEPGVPTT---KTPAA---TKPEMTTTAKDKTT 920
Query: 90 AAQPHTEIPEGTTAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGS---DDKKAKGAD 146
T PE TTA +T + ++ T++++ + + T + D K
Sbjct: 921 ERDLRTT-PETTTAAPKMTKETATTTEKT----TESKITATTTQVTSTTTQDTTPFKITT 975
Query: 147 GKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTP 206
KT P+ T+ T P + +P DR+
Sbjct: 976 LKTTTLAPK----------VTTTKKTITTTEIMNKPEETAKPK---DRA----------T 1012
Query: 207 GSRSRTPSLPTPPTREPKKVAVVRTP--------PKSPSSAKSRLQTAPVPMPDLKNVKS 258
S++ TP P PT+ PKK + P PK+ + + T P P + ++
Sbjct: 1013 NSKATTPK-PQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEA 1071
Query: 259 KIGSTENLKHQPGGGKVQIINKKLDLSNVQSK 290
+ +T P V++ K D + +
Sbjct: 1072 MLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGE 1103
>gi|113416996 PREDICTED: ankyrin repeat domain 33B [Homo sapiens]
Length = 1006
Score = 53.9 bits (128), Expect = 3e-07
Identities = 55/198 (27%), Positives = 80/198 (40%), Gaps = 27/198 (13%)
Query: 46 SPLQTPTEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGA-PGKQAAAQPHTEIPE----G 100
+P Q PT SE PG + +S T TAPL P K+ P ++ P
Sbjct: 316 TPPQQPTAPSSEWPGPQ----RSPGTGPRWTAPLPRPAPLPAKRPGDSPASKRPRPGGVS 371
Query: 101 TTAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKT--KIATPRGAA 158
A + G+ P EAAG ++ + D G + KG +GK + +PR A
Sbjct: 372 PEARDPPKGENPLCSSEAAGETGPTQV--RGPDALGGGRLQGKGREGKAPGEGVSPRPAP 429
Query: 159 PPGQKGQANATRIPAKTPPAPKT--------PPSSGEPPKSGDRSGYSSPGSPGT----P 206
P + G+ +R P P+T P S E ++G + G P
Sbjct: 430 P--RLGKPPRSRPPQGLAQPPETFFFERSRLVPVSAELERAGHGFSGDAEARSGDLGARP 487
Query: 207 GSRSRTPSLPTPPTREPK 224
SRS PS P PP ++P+
Sbjct: 488 ASRSSLPSAPAPPAQQPQ 505
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 53.5 bits (127), Expect = 4e-07
Identities = 63/233 (27%), Positives = 89/233 (38%), Gaps = 32/233 (13%)
Query: 21 GDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPGSETSDAKSTPTAEDVTAPLV 80
G RK + H E A + S G + P S + + +TP + +
Sbjct: 204 GPRKSVSSASEHSTTEPSPAARRRPS-----AGGGLQRPASRSLSSSATPLSSPARSGPS 258
Query: 81 DEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAA--GHVTQARMVSKSKDGTGSD 138
G P +A A P P+G A TP +D A G ++ + + + S GT
Sbjct: 259 ARGTP--RAPAHPSQPKPKGLQALRPP-QVTPPRKDAAPALGPLSSSPLATPSPSGT--- 312
Query: 139 DKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYS 198
KA+ ATP A P P P P PPS PP S +
Sbjct: 313 --KARPVPPPDNAATPLPATLPPS---------PPLATPLPLAPPSPSAPP-----SLQT 356
Query: 199 SPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKS-RLQTAPVPM 250
P P TP S++ PS+ TPP + P + + P + P S S LQ P P+
Sbjct: 357 LPSPPATPPSQA-PPSMTTPPMQAPPSLQTI-PPIQVPHSLTSPSLQAPPSPL 407
Score = 42.7 bits (99), Expect = 7e-04
Identities = 55/225 (24%), Positives = 81/225 (36%), Gaps = 21/225 (9%)
Query: 46 SPLQTPTEDGSEEPGSETSDAK-STPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAE 104
SPL TP+ A S P + V AP +P +A P ++ P A
Sbjct: 643 SPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAP 702
Query: 105 EAGIGDTPSLEDEAAGHVTQ--------ARMVSKSKDGTGSDDKKAKGADGKTKIATPRG 156
+ +P + T A + + + A ++ P
Sbjct: 703 PLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVP-PLL 761
Query: 157 AAPPGQKGQANATRIPAK--TPPAPKTPPSSGEPPKSGDRSGYSS-PG-SPGTPGSRSRT 212
AAPP Q + +P P P+ PP+ PP S +S PG +P +P +
Sbjct: 762 AAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPM 821
Query: 213 PSLPTPPTREPKKVA-----VVRTPPKSPSSAKSRLQTAPVPMPD 252
L TPP + P +A V +PP SP+ R P P PD
Sbjct: 822 SPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPR--RPPTPGPD 864
Score = 40.0 bits (92), Expect = 0.004
Identities = 50/191 (26%), Positives = 70/191 (36%), Gaps = 26/191 (13%)
Query: 85 PGKQAAAQPHTEIPE---GTTAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKK 141
P A +P TE P + +E + +P+ + R S+S + +
Sbjct: 192 PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATP-LS 250
Query: 142 AKGADGKTKIATPRGAAPPGQ---KGQANATRIPAKTPP----APKTPPSSGEPPKSGDR 194
+ G + TPR A P Q KG A R P TPP AP P S P +
Sbjct: 251 SPARSGPSARGTPRAPAHPSQPKPKG-LQALRPPQVTPPRKDAAPALGPLSSSPLATPSP 309
Query: 195 SGYSS-----PGSPGTPGSRSRTPSLP--TP-------PTREPKKVAVVRTPPKSPSSAK 240
SG + P + TP + PS P TP P+ P + P PS A
Sbjct: 310 SGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAP 369
Query: 241 SRLQTAPVPMP 251
+ T P+ P
Sbjct: 370 PSMTTPPMQAP 380
Score = 38.9 bits (89), Expect = 0.009
Identities = 31/108 (28%), Positives = 42/108 (38%), Gaps = 10/108 (9%)
Query: 151 IATPRGAAPPGQKGQANATRIPAKTPPAPKT-------PPSSGEPPKSGDRSGYSSPGSP 203
+A P APP + + +P AP P S PP ++ +S P SP
Sbjct: 625 LALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFS-PPPSPPVQAPFSPPASP 683
Query: 204 GTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMP 251
P S S TP PP+ + V +PP SP + S P P
Sbjct: 684 --PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPP 729
Score = 37.4 bits (85), Expect = 0.027
Identities = 34/113 (30%), Positives = 46/113 (40%), Gaps = 24/113 (21%)
Query: 151 IATPRGAAP-PGQKGQANATRIPAKTP-----PAPKTPPSSGEPPKSGDRSGYSSPGSPG 204
+ TP AP P Q + T P +TP P P+ PP+ PP G P P
Sbjct: 558 LETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQG------LPSPPL 611
Query: 205 TPGSRSRTPSLPTPPTREPKKVAV--VRTPPKSPSSAKSRLQTAPVPMPDLKN 255
+P L TPP + P +A+ ++ PP P+S L P P N
Sbjct: 612 SP--------LATPPPQAPPXLALPPLQAPPSPPASPP--LSPLATPSPQAPN 654
Score = 35.0 bits (79), Expect = 0.14
Identities = 28/102 (27%), Positives = 37/102 (36%), Gaps = 14/102 (13%)
Query: 152 ATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSR 211
ATP APP A ++P P +P PS+ PP++ P +
Sbjct: 689 ATPPSQAPPSLA--APPLQVPPSPPASPPMSPSATPPPQA----------PPPLAAPPLQ 736
Query: 212 TPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDL 253
P P+PP P + P P A LQ P P L
Sbjct: 737 VP--PSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASL 776
Score = 32.0 bits (71), Expect = 1.1
Identities = 26/105 (24%), Positives = 41/105 (39%), Gaps = 8/105 (7%)
Query: 149 TKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGS 208
+ IATP APP P + P+P P + PP++ +P +P +
Sbjct: 585 SSIATPPPQAPPALASP------PLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPA 638
Query: 209 RSRTPSLPTPPTREPKKVAV--VRTPPKSPSSAKSRLQTAPVPMP 251
L TP + P +AV ++ P P S + +P P
Sbjct: 639 SPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP 683
Score = 29.3 bits (64), Expect = 7.5
Identities = 34/123 (27%), Positives = 53/123 (43%), Gaps = 17/123 (13%)
Query: 142 AKGADGKTKIATPRG----AAPPGQKGQANATRIPAKTPPAPKT-PPSSGEPPKSGDRSG 196
A GA G+ +A G A P +A TR + P + PP+SG ++
Sbjct: 49 AAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKN 108
Query: 197 YSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRT---------PPKSPSSAKSRLQTA- 246
+SPG +PG S T + P P ++ +++ T P +S SA +R T+
Sbjct: 109 -TSPGPVSSPGRASGT-TRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSG 166
Query: 247 PVP 249
P P
Sbjct: 167 PTP 169
Score = 28.9 bits (63), Expect = 9.7
Identities = 51/225 (22%), Positives = 82/225 (36%), Gaps = 36/225 (16%)
Query: 46 SPLQTPTEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEE 105
SP TP S+ P S T+ P + P+ + + P + + +
Sbjct: 359 SPPATPP---SQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQAT 415
Query: 106 AGIGDTPSLEDE-----AAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPP 160
+G +P+L+ + TQA + S S+ + D A ++ P A+PP
Sbjct: 416 TSLG-SPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAP----LSLP--ASPP 468
Query: 161 GQKGQANATRIPAKTP--------------PAPKTPPSSGEPPKSGDRSGYSSPGSPGTP 206
Q + A P +P +P+ P SS P +S + P S TP
Sbjct: 469 LQTSLSPAVS-PLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPP-SLQTP 526
Query: 207 GSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMP 251
+ TP L P+ P + P +P L+T P P P
Sbjct: 527 PASLTTPPLENLPSLAPPPLQTASAPLTTP-----HLETPPCPAP 566
Score = 28.9 bits (63), Expect = 9.7
Identities = 54/226 (23%), Positives = 73/226 (32%), Gaps = 33/226 (14%)
Query: 41 AGLKESPLQTPTEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEI--P 98
A L SPL TP + +P A AP + P T + P
Sbjct: 817 ASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQ------APRRPPTPGPDTSVSGP 870
Query: 99 EGTTAEEAGIGDTPSLEDEA-------AGHVTQARMVSKSKDGTGSDDKKAKGA----DG 147
T A G PS + AGH + A + G S + A D
Sbjct: 871 RLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDA 930
Query: 148 KTKIATP----RGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPG-S 202
+ P RG APP A +P PP++G G + Y + G
Sbjct: 931 ELAACHPAAWSRGPAPPLAFRGAPGAPLP--------WPPATGPGSADGLCTIYETEGPE 982
Query: 203 PGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPV 248
TP + P P+P T K A S S ++RL P+
Sbjct: 983 SATPAPGALDPG-PSPGTSGGKAAAGAGAGASSRSPKQARLGELPL 1027
Score = 28.9 bits (63), Expect = 9.7
Identities = 26/103 (25%), Positives = 34/103 (33%), Gaps = 6/103 (5%)
Query: 151 IATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRS 210
+ PR PG + R+ P P PP PP S S P G S +
Sbjct: 852 LQAPRRPPTPGPDTSVSGPRLTLALAPGP--PP----PPSRSPSSTLSGPDLAGHSSSAT 905
Query: 211 RTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDL 253
TP P+ A PP + +A + P P L
Sbjct: 906 STPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPL 948
>gi|59806361 hypothetical protein LOC387104 [Homo sapiens]
Length = 947
Score = 53.1 bits (126), Expect = 5e-07
Identities = 60/238 (25%), Positives = 84/238 (35%), Gaps = 27/238 (11%)
Query: 60 GSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAA 119
G+ + A ++P A A L EG+ KQ AQ + + + +P
Sbjct: 8 GAAPATAAASPAAAATEARLHPEGSSRKQQRAQSPARPRDSSLRQTIAATRSPVGAGTKL 67
Query: 120 GHVTQARMVSKSKDG--TGS---DDKKAKGADGKTKIATP---RGAAPPGQKGQANATRI 171
V Q ++ + + G TGS +G G + ATP +GAAP + A A
Sbjct: 68 NSVRQQQLQQQQQQGNKTGSRTGPPASIRGGGGGAEKATPLAPKGAAPGAVQPVAGAEAA 127
Query: 172 PAKT--------PPAPKTPPSS--------GEPPKSGDRSGYSSPGSPGTPGSRSRTPSL 215
PA T P P+ PP GEPP G+ G G GS R
Sbjct: 128 PAATLAALGGRRPGPPEEPPRELESVPSKLGEPPPLGEGGGGGGEGGGAGGGSGEREGGA 187
Query: 216 PTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGG 273
P PP + VR + S + +P P GS + GGG
Sbjct: 188 PQPPPPRGWRGKGVRAQQRGGSGGEG---ASPSPSSSSAGKTPGTGSRNSGSGVAGGG 242
>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
Length = 1427
Score = 52.4 bits (124), Expect = 8e-07
Identities = 52/214 (24%), Positives = 82/214 (38%), Gaps = 11/214 (5%)
Query: 30 TMHQDQEGDTDAGLKESPLQTPTEDGSEEPGSE--TSDAKSTPTAEDVTAPLVDEGAPGK 87
T+H +E DT A ++ S + P + P E TS A + PT E+ T+P P +
Sbjct: 980 TVHAPEEPDT-AAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEE 1038
Query: 88 QAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADG 147
+ PE T+ A + AA T S + ++ + A
Sbjct: 1039 PTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAV 1098
Query: 148 KT--KIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGT 205
T + +P A P ++ + PA P P+ P S + + + +P P
Sbjct: 1099 PTPEEPTSPAAAVPTPEEPAS-----PAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTP 1153
Query: 206 PGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSA 239
S S ++PT P A V TP +S S A
Sbjct: 1154 EESASAAVAVPT-PEESASPAAAVPTPAESASFA 1186
Score = 45.1 bits (105), Expect = 1e-04
Identities = 51/231 (22%), Positives = 81/231 (35%), Gaps = 17/231 (7%)
Query: 36 EGDTDAGLKESPLQTPTEDGSEEPGSE--TSDAKSTPTAEDVTAPLVDEGAPGKQAAAQP 93
E T P + PT + P E TS A + PT E+ T+P P + +
Sbjct: 1024 EEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAA 1083
Query: 94 HTEIPEGTTAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKT--KI 151
PE T+ A + AA T S + ++ + A T +
Sbjct: 1084 AVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEP 1143
Query: 152 ATPRGAAPPGQKGQANATRIPA---KTPPAPKTPPSSGEPPKSGDRSGYSSPGSPG---- 204
A P A P ++ + A +P PA P + + + P SP
Sbjct: 1144 AFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVP 1203
Query: 205 TPGSRSRT------PSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVP 249
TP + T P+ P + EP +A + P+ P+S + + T P
Sbjct: 1204 TPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEP 1254
Score = 42.0 bits (97), Expect = 0.001
Identities = 56/242 (23%), Positives = 87/242 (35%), Gaps = 30/242 (12%)
Query: 35 QEGDTDAGLKESPLQT--PTEDGSEEPGSETSDAKSTP--TAEDVTAPLVDEGAPGKQ-- 88
+E D A +P + P S G+ A S+P TA V A + EG
Sbjct: 892 EEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGF 951
Query: 89 -------AAAQPHTE---IPEGTTAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSD 138
A P TE PEG + P D AA V+ + +
Sbjct: 952 SPEWAALAITVPITEEDGTPEGPVTPATTV-HAPEEPDTAAVRVSTPEEPASPAAAVPTP 1010
Query: 139 DKKAKGADG---KTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPK--SGD 193
++ A + +P A PP ++ + A +P TP P +P ++ P+ +
Sbjct: 1011 EEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVP--TPEEPTSPAAAVPTPEEPTSP 1068
Query: 194 RSGYSSPGSPGTPGSRSRTPSLPTPPT------REPKKVAVVRTPPKSPSSAKSRLQTAP 247
+ +P P +P + TP PT P EP A P+ P+S + + T
Sbjct: 1069 AAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPE 1128
Query: 248 VP 249
P
Sbjct: 1129 EP 1130
>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
Length = 1466
Score = 50.8 bits (120), Expect = 2e-06
Identities = 54/176 (30%), Positives = 70/176 (39%), Gaps = 24/176 (13%)
Query: 59 PGSETSDAKS----TPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSL 114
PG++ D K P A + + GAPG + A P+ E A E G P+
Sbjct: 458 PGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERG-APGPAG 516
Query: 115 EDEAAGHVTQ--------ARMVSKSKDGTGSDDKKAK-GADGKTKIATPRGAAPPGQKGQ 165
AAG + R + S G GSD K G+ G++ P G P G +GQ
Sbjct: 517 PRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPG--PSGPRGQ 574
Query: 166 ANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRT-PSLPTPPT 220
P PK + G P K+G+R G PG G PG T P P PT
Sbjct: 575 PGVMGFPG-----PKG--NDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPT 623
Score = 50.4 bits (119), Expect = 3e-06
Identities = 55/207 (26%), Positives = 72/207 (34%), Gaps = 16/207 (7%)
Query: 47 PLQTPTEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEA 106
P +P +DG P T P + V+ P D G PG++ + P + P G
Sbjct: 895 PSGSPGKDGPPGPAGNTG----APGSPGVSGPKGDAGQPGEKGS--PGAQGPPGAPGP-L 947
Query: 107 GIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQA 166
GI A S G + K GA+G + P G P G G A
Sbjct: 948 GIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKP-GANGLSGERGPPG--PQGLPGLA 1004
Query: 167 NATRIPAK--TPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPK 224
P + P + P G P GDR SPG+PG PG P P P K
Sbjct: 1005 GTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGH----PGPPGPVGPAGK 1060
Query: 225 KVAVVRTPPKSPSSAKSRLQTAPVPMP 251
+ P P+ A + P P
Sbjct: 1061 SGDRGESGPAGPAGAPGPAGSRGAPGP 1087
Score = 40.4 bits (93), Expect = 0.003
Identities = 38/132 (28%), Positives = 48/132 (36%), Gaps = 30/132 (22%)
Query: 81 DEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDK 140
+ G PG+ A P P G E P L A ++ DG
Sbjct: 286 ENGLPGENGAPGPMG--PRGAPGERG----RPGLPGAAG---------ARGNDG------ 324
Query: 141 KAKGADGKTKIATPRGAA----PPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSG 196
A+G+DG+ P G A PG KG+ PA +P + P GEP G
Sbjct: 325 -ARGSDGQPGPPGPPGTAGFPGSPGAKGEVG----PAGSPGSNGAPGQRGEPGPQGHAGA 379
Query: 197 YSSPGSPGTPGS 208
PG PG GS
Sbjct: 380 QGPPGPPGINGS 391
Score = 40.4 bits (93), Expect = 0.003
Identities = 45/154 (29%), Positives = 56/154 (36%), Gaps = 23/154 (14%)
Query: 83 GAPGKQAA-AQPHTEIPEGTTAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKK 141
G PGK A +P G EAGI P + E + + G +
Sbjct: 432 GEPGKNGAKGEPGPRGERG----EAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGE--- 484
Query: 142 AKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPP--APKTPPSSGEPPKSGDRS---- 195
+GA G A P G PG+KG A P P A P G P G R
Sbjct: 485 -RGAPGFRGPAGPNGI--PGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGS 541
Query: 196 --GYSSPGSPGTPGSRSRT----PSLPTPPTREP 223
G S G PG PGS+ + P P+ P +P
Sbjct: 542 PGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQP 575
Score = 40.0 bits (92), Expect = 0.004
Identities = 50/185 (27%), Positives = 61/185 (32%), Gaps = 30/185 (16%)
Query: 83 GAPGKQAAAQPHTEIPEGTTAEEA-----GIGDTPSLED---EAAGHVTQARMVSKSKDG 134
GAPG + A P PEG G TP L+ E G + K + G
Sbjct: 690 GAPGLRGGAGPPG--PEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPG 747
Query: 135 -TGSDDKKAK-GADGKT-KIATPRGAAPPGQKGQANATRIPAKTPPA------------- 178
G+D K G G T I P A PG KG+ A +P P
Sbjct: 748 GPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPG 807
Query: 179 ----PKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPK 234
P P +GEP G+R G G PG P+ V R P
Sbjct: 808 PAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPG 867
Query: 235 SPSSA 239
P +A
Sbjct: 868 GPGAA 872
Score = 37.4 bits (85), Expect = 0.027
Identities = 49/172 (28%), Positives = 55/172 (31%), Gaps = 36/172 (20%)
Query: 82 EGAPGKQAAAQPHTEIPEGTTAEEAGIGDT----------------PSLEDEAAGHVTQA 125
+G PGK P P G T GDT P E+ G
Sbjct: 605 QGPPGKNGETGPQG--PPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPK 662
Query: 126 RMVSKSKDGTGSDDKKAKGADGKTKIATPRG----AAPPGQKGQANATRIPAKTPPAPKT 181
G D A G G +A G A PPG +G A P P A T
Sbjct: 663 GDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGP-PGAAGT 721
Query: 182 PPSSGEPPKSGDRSGYSSP------GSPGTPGS----RSRTPSLPTPPTREP 223
P G P G+R G SP G PG PG+ P PT P P
Sbjct: 722 PGLQGMP---GERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPP 770
Score = 36.6 bits (83), Expect = 0.047
Identities = 45/157 (28%), Positives = 53/157 (33%), Gaps = 31/157 (19%)
Query: 83 GAPGKQAAAQPHTEIPE-GTTAEE--AGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDD 139
GAPG A P E G T AG P E G K G+
Sbjct: 783 GAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGG-----------KGERGAPG 831
Query: 140 KKAKGADGKTKIATPRG----AAPPGQKGQANATRIPAKTPPA--------PKTPPSSGE 187
+K +G G +A P G A PPG +G P A P P S+G
Sbjct: 832 EKGEG--GPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGN 889
Query: 188 PPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPK 224
P G SPG G PG T + +P PK
Sbjct: 890 PGPPGPSG---SPGKDGPPGPAGNTGAPGSPGVSGPK 923
Score = 36.2 bits (82), Expect = 0.061
Identities = 45/175 (25%), Positives = 57/175 (32%), Gaps = 15/175 (8%)
Query: 37 GDTDAGLKESPLQTPTEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTE 96
G D G SP PG KS E + P GAPG +
Sbjct: 1030 GKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGE--SGPAGPAGAPGPAGS------ 1081
Query: 97 IPEGTTAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAK-GADGKTKIATPR 155
G + GD + A + R + GS + GA G A PR
Sbjct: 1082 --RGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPR 1139
Query: 156 G-AAPPGQKGQANATRIPAKT-PPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGS 208
G P G G+ + P PP P+ + GE G PG PG PG+
Sbjct: 1140 GPVGPSGPPGKDGTSGHPGPIGPPGPRG--NRGERGSEGSPGHPGQPGPPGPPGA 1192
Score = 35.4 bits (80), Expect = 0.10
Identities = 22/53 (41%), Positives = 26/53 (49%), Gaps = 2/53 (3%)
Query: 169 TRIP-AKTPPAPKTPPSS-GEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPP 219
TR P + P PK P G P ++GD PGSPG+PG S PT P
Sbjct: 96 TRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGP 148
Score = 35.4 bits (80), Expect = 0.10
Identities = 53/229 (23%), Positives = 73/229 (31%), Gaps = 34/229 (14%)
Query: 15 AGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPGSETS--DAKSTPTA 72
AG G K G+ ++G+T A + P E+G+ P + P
Sbjct: 254 AGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGL 313
Query: 73 EDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAGHVTQARMVSKSK 132
++GA G QP P GT AG +P + E + + +
Sbjct: 314 PGAAGARGNDGARGSDG--QPGPPGPPGT----AGFPGSPGAKGEVGPAGSPGSNGAPGQ 367
Query: 133 DGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIP-------AKTPPAPKTPPSS 185
G A GA G P PG KG+ IP A+ PP P +
Sbjct: 368 RGEPGPQGHA-GAQGPP--GPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGA 424
Query: 186 ----------------GEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTP 218
GEP G+R PG PG G + S P
Sbjct: 425 PGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEP 473
Score = 35.0 bits (79), Expect = 0.14
Identities = 50/187 (26%), Positives = 63/187 (33%), Gaps = 39/187 (20%)
Query: 56 SEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAE--------EAG 107
S PGS S P E A G PG A P P G E E G
Sbjct: 188 SGHPGSPGSPGYQGPPGEPGQAG--PSGPPGPPGAIGPSG--PAGKDGESGRPGRPGERG 243
Query: 108 IGDTPSLEDEAAGHVTQARMVSKSKDG-------TGSDDKKAK----GADGKTKIATPRG 156
+ P ++ A + DG TG+ K + G +G PRG
Sbjct: 244 LPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRG 303
Query: 157 AAPPGQKGQ----------ANATRIPAKTPPAPKTPPSS----GEPPKSGDRSGYSSPGS 202
A PG++G+ N + P P PP + G P G+ SPGS
Sbjct: 304 A--PGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGS 361
Query: 203 PGTPGSR 209
G PG R
Sbjct: 362 NGAPGQR 368
Score = 33.5 bits (75), Expect = 0.40
Identities = 39/167 (23%), Positives = 62/167 (37%), Gaps = 32/167 (19%)
Query: 132 KDGT--GSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPA-----PKTPPS 184
+DG+ G D+ G+ G P PPG G A + ++ PA P S
Sbjct: 1024 RDGSPGGKGDRGENGSPGAP--GAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGS 1081
Query: 185 SGEPPKSGDRS-----------------GY-SSPGSPGTPGSRSRTPSLPTPPTREPKKV 226
G P G R G+ +PG+PG+PG + ++ +P P+
Sbjct: 1082 RGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGP 1141
Query: 227 AVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKH--QPG 271
PP ++ P+ P + + + GS + H QPG
Sbjct: 1142 VGPSGPPGKDGTSG---HPGPIGPPGPRGNRGERGSEGSPGHPGQPG 1185
Score = 32.3 bits (72), Expect = 0.88
Identities = 38/151 (25%), Positives = 52/151 (34%), Gaps = 19/151 (12%)
Query: 83 GAPGKQA-AAQPHTEIPEGTTAEEAGIG-DTPSLEDEAAGHVTQARMVSKSKDGTGSDDK 140
G PG Q + +P P G + +G P D A G K+ + G
Sbjct: 552 GPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPG---------KNGERGGPGGP 602
Query: 141 KAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPK----TPPSSGEPPKSGDRSG 196
+G GK P+G PPG G PP P+ P + G P ++G
Sbjct: 603 GPQGPPGKNGETGPQG--PPGPTGPGGDKGDTG--PPGPQGLQGLPGTGGPPGENGKPGE 658
Query: 197 YSSPGSPGTPGSRSRTPSLPTPPTREPKKVA 227
G G PG+ P R P +A
Sbjct: 659 PGPKGDAGAPGAPGGKGDAGAPGERGPPGLA 689
Score = 32.0 bits (71), Expect = 1.1
Identities = 25/74 (33%), Positives = 28/74 (37%), Gaps = 15/74 (20%)
Query: 146 DGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGT 205
D K+ +A A PG G PP P PP + P S GY P PG
Sbjct: 159 DVKSGVAVGGLAGYPGPAG-----------PPGPPGPPGTSGHPGSPGSPGYQGP--PGE 205
Query: 206 PGSRSRTPSLPTPP 219
PG PS P P
Sbjct: 206 PGQAG--PSGPPGP 217
Score = 31.2 bits (69), Expect = 2.0
Identities = 19/51 (37%), Positives = 21/51 (41%), Gaps = 11/51 (21%)
Query: 176 PPAPKTPPSS-------GEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPP 219
P AP PP+ G+P G PG PG PGS P P PP
Sbjct: 92 PTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGS----PGSPGPP 138
Score = 29.6 bits (65), Expect = 5.7
Identities = 17/51 (33%), Positives = 19/51 (37%), Gaps = 10/51 (19%)
Query: 154 PRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPG 204
P G P G KG P P P +G+P G SPG PG
Sbjct: 99 PNGQGPQGPKGD----------PGPPGIPGRNGDPGIPGQPGSPGSPGPPG 139
Score = 29.6 bits (65), Expect = 5.7
Identities = 41/170 (24%), Positives = 57/170 (33%), Gaps = 10/170 (5%)
Query: 55 GSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAA-AQPHTEIPEGTTAEEAGIGDTPS 113
G PG + D P + + G PG+ +P + G G GD +
Sbjct: 621 GPTGPGGDKGDT-GPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGA 679
Query: 114 LEDEAAGHVTQARMVSKSKDGTGSDDKK-AKGADGKTKIA-TPRGAAPPGQKGQANATRI 171
+ + A + G + K A G G A TP PG++G +
Sbjct: 680 PGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPG- 738
Query: 172 PAKTPPAPKTPPSSGEPPKSGDR---SGYSSPGSPGTPGSRSR--TPSLP 216
P P P + G P K G R PG G PG + P LP
Sbjct: 739 PKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLP 788
>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
Length = 2968
Score = 50.1 bits (118), Expect = 4e-06
Identities = 56/277 (20%), Positives = 102/277 (36%), Gaps = 21/277 (7%)
Query: 4 PRQEFEVME--DHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPGS 61
P +E E++ DH G +K + + +D AG + P ++ GS P +
Sbjct: 2454 PGEEAELLVKLDHEGVTSPKSKKAKEALLLREDP----GAGGWQEP-KSLLSLGSYPPAA 2508
Query: 62 ETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAGH 121
+S+ K+ P + L E PG + + P+ AE+ G ++ S ++G
Sbjct: 2509 GSSEPKA-PWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGS 2567
Query: 122 VTQARMVSKSKDGTGSDDKKAKGADG-------KTKIATPRGAAPPGQKGQANATRIPAK 174
+ + S S T +++ K DG A+ R A+P ++++ +
Sbjct: 2568 SSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSS 2627
Query: 175 TPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPK 234
+ + + SS S S SS S + S S + S + T E +
Sbjct: 2628 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAP 2687
Query: 235 SPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPG 271
+P++ S P + G H PG
Sbjct: 2688 APTAGPSAQAALPT------KATKQAGKARPSAHSPG 2718
Score = 42.7 bits (99), Expect = 7e-04
Identities = 51/260 (19%), Positives = 100/260 (38%), Gaps = 16/260 (6%)
Query: 13 DHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPGSETSDAKSTPTA 72
D A G G + G D+ G +ES + + GS S +S + S
Sbjct: 2524 DLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEG 2583
Query: 73 EDVTAPLVDEGAP--GKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAGHVTQARMVSK 130
E+ D G G+ +A +++ + + S ++ + + S
Sbjct: 2584 EEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2643
Query: 131 SKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGE--P 188
S + S + + + ++ ++ + ++ A PAP PS+ P
Sbjct: 2644 SSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAA---PAPTAGPSAQAALP 2700
Query: 189 PKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSR-LQTAP 247
K+ ++G + P S +PG ++ P PP + + + PK+ + AKSR +
Sbjct: 2701 TKATKQAGKARP-SAHSPGKKTPAPQPQAPPPQPTQPLQ-----PKAQAGAKSRPKKREG 2754
Query: 248 VPMPDLKNV--KSKIGSTEN 265
V +P K + + ++ S EN
Sbjct: 2755 VHLPTTKELAKRQRLPSVEN 2774
Score = 41.6 bits (96), Expect = 0.001
Identities = 76/302 (25%), Positives = 109/302 (36%), Gaps = 46/302 (15%)
Query: 131 SKDGTGSDDKKAKGADGKTKIATPRGAAPPGQ-KGQANAT--------RIPAKTPPA--- 178
SKD D G++ A RG P + KG AT +P+ TP A
Sbjct: 2308 SKDTGEGKDGGTAGSEEPGAKARGRGRKPSAKAKGDRAATLEEGNPTDEVPS-TPLALEP 2366
Query: 179 PKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSS 238
TP S PP+ D+ + P P P+ + P EP P + S
Sbjct: 2367 SSTPGSKKSPPEPVDKRAKAPKARPAPPQPSPAPPAFTSCPAPEP----FAELPAPATSL 2422
Query: 239 AKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSKCGSKDN-- 296
A + L T P P K ++ S +PG ++ KLD V S K
Sbjct: 2423 APAPLITMPATRPKPKKARAAEESGAKGPRRPGEEAELLV--KLDHEGVTSPKSKKAKEA 2480
Query: 297 --IKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKI 354
++ PG G Q +P L SLG+ + P G E K+ D
Sbjct: 2481 LLLREDPGAGGWQ---EPKSLL-------SLGS--YPPAAGSSEPKAPWPKATD------ 2522
Query: 355 GSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSNVSST 414
++ PG G ++ + A+A+ D E S SG +S S+ SS+
Sbjct: 2523 ---GDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSS--SSSSSS 2577
Query: 415 GS 416
GS
Sbjct: 2578 GS 2579
>gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]
Length = 1489
Score = 50.1 bits (118), Expect = 4e-06
Identities = 47/157 (29%), Positives = 64/157 (40%), Gaps = 14/157 (8%)
Query: 106 AGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATP-RGAAPPGQKG 164
AG G P+L H + +++ G+ +D A A + P GAA P G
Sbjct: 719 AGWGGHPAL---GCPHPPEDDSSLRAERGSLADLPMAPPASAPPEFLDPLMGAAAPQYPG 775
Query: 165 QANATRIPAKTPP--APKTPPSSGEPPK--SGDRSGYSSPG-SPGTPGSRSRTP-----S 214
+ P PP AP P +S +PP + SG SSPG PG G + TP +
Sbjct: 776 RGPPPAPPPPPPPPRAPADPAASPDPPSAVASPGSGLSSPGPKPGDSGYETETPFSPEGA 835
Query: 215 LPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMP 251
P E + V R PP+ P R P P+P
Sbjct: 836 FPGGGAAEEEGVPRPRAPPEPPDPGAPRPPPDPGPLP 872
Score = 39.7 bits (91), Expect = 0.006
Identities = 58/257 (22%), Positives = 86/257 (33%), Gaps = 51/257 (19%)
Query: 25 DQGGYTMHQDQEGDTDAGLKESP---LQTPTEDGSE----EPGSETSDAKSTPTAEDVTA 77
+ GG ++ E + G +P +TP G EP ETS ++ + V++
Sbjct: 1034 ENGGLRFPRNTERPPETGPWRAPGPWEKTPESWGPAPTIGEPAPETSLERAPAPSAVVSS 1093
Query: 78 PLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGS 137
E APG A + + GT G P G G
Sbjct: 1094 RNGGETAPGPLGPAPKNGTLEPGTERRAPETGGAPRAP------------------GAGR 1135
Query: 138 DDKKAKGADGKTKIATPRGAAPPGQKGQANATRI-----------PAKTPPAPKTPPSSG 186
D G+ G+ + T G AP G G + P PP P+ P
Sbjct: 1136 LDL---GSGGRAPVGT--GTAPGGGPGSGVDAKAGWVDNTRPQPPPPPLPPPPEAQPRRL 1190
Query: 187 EPPKSGDRSGYSSPGSPGTPGSRSRTPSL------PTPPTRE----PKKVAVVRTPPKSP 236
EP R + G PG P SR+ + P P R+ P+ + P +
Sbjct: 1191 EPAPPRARPEVAPEGEPGAPDSRAGGDTALSGDGDPPKPERKGPEMPRLFLDLGPPQGNS 1250
Query: 237 SSAKSRLQTAPVPMPDL 253
K+RL + +P L
Sbjct: 1251 EQIKARLSRLSLALPPL 1267
Score = 31.6 bits (70), Expect = 1.5
Identities = 53/191 (27%), Positives = 65/191 (34%), Gaps = 38/191 (19%)
Query: 35 QEGDTDAGLKESPL---QTPTEDGSE---EPGSETSDAKSTPTAE---DVTAPLVDEGAP 85
+ GD AG P P ED S E GS +D P A + PL+ AP
Sbjct: 713 ERGDAVAGWGGHPALGCPHPPEDDSSLRAERGS-LADLPMAPPASAPPEFLDPLMGAAAP 771
Query: 86 GKQAA----AQPHTEIPEGTTAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKK 141
A P P A+ A D PS V+ G S K
Sbjct: 772 QYPGRGPPPAPPPPPPPPRAPADPAASPDPPSA-------------VASPGSGLSSPGPK 818
Query: 142 AKGADGKTKIA-TPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSP 200
+ +T+ +P GA P G G A +P P AP PP G P D P
Sbjct: 819 PGDSGYETETPFSPEGAFPGG--GAAEEEGVPR--PRAPPEPPDPGAPRPPPD------P 868
Query: 201 GSPGTPGSRSR 211
G PG R +
Sbjct: 869 GPLPLPGPREK 879
Score = 31.6 bits (70), Expect = 1.5
Identities = 52/195 (26%), Positives = 67/195 (34%), Gaps = 44/195 (22%)
Query: 53 EDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGK-QAAAQPHTEIPEGTTAEEA----G 107
EDG +E E D E+ AP G G +A A P + A+ A G
Sbjct: 1305 EDGEDEDEDEEED-------EEAAAPGAAAGPRGPGRARAAPVPVVVSSADADAARPLRG 1357
Query: 108 IGDTPSLEDEAAGHVTQAR--MVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQ 165
+ +P DE + + MVS D T + + + A P G P
Sbjct: 1358 LLKSPRGADEPEDSELERKRKMVSFHGDVTVYLFDQETPTNELSVQAPPEGDTDPS---- 1413
Query: 166 ANATRIPAKTPPAPKTPPSSGEP----PKSGDRSGYS-----------SPGSPGTPGSRS 210
TPPAP TPP P P + G S PG P S
Sbjct: 1414 ---------TPPAPPTPPHPATPGDGFPSNDSGFGGSFEWAEDFPLLPPPGPPLCFSRFS 1464
Query: 211 RTPSL--PTPPTREP 223
+P+L P PP R P
Sbjct: 1465 VSPALETPGPPARAP 1479
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 49.7 bits (117), Expect = 5e-06
Identities = 65/245 (26%), Positives = 91/245 (37%), Gaps = 29/245 (11%)
Query: 21 GDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPGSETSDAKSTPTAEDVTAPLV 80
G RK + H E A + S G + P S + + +TP + +
Sbjct: 204 GPRKSVSSASEHSTTEPSPAARRRPS-----AGGGLQRPASRSLSSSATPLSSPARSGPS 258
Query: 81 DEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDK 140
G P +A A P P+G A TP +D A +S S T S
Sbjct: 259 ARGTP--RAPAHPSQPKPKGLQALRPP-QVTPPRKDAAPA----LGPLSSSPLATPSPSA 311
Query: 141 KAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPS---SGEPPKSGDRSGY 197
+ T ATP ++ Q AT +P PP+P PPS PP +
Sbjct: 312 ALQSQAPPTLPATPHSSSLTCQL----ATPLPL-APPSPSAPPSLQTLPSPPATPPSQAT 366
Query: 198 SSPGSPGTPGSRSRTPSLP-----TPPTREPKKVAV--VRTPPKSPSSAKSRLQTAPVPM 250
+S GSP + S PS P TPP + P +A+ ++ PP P+S L P
Sbjct: 367 TSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPP--LSPLATPS 424
Query: 251 PDLKN 255
P N
Sbjct: 425 PQAPN 429
Score = 44.3 bits (103), Expect = 2e-04
Identities = 53/210 (25%), Positives = 68/210 (32%), Gaps = 35/210 (16%)
Query: 46 SPLQTPTEDGSEEPGSETSDAK-STPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAE 104
SPL TP+ A S P + V AP +P +A P ++ P A
Sbjct: 418 SPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAP 477
Query: 105 EAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKG 164
+ +P + T A P AAPP Q
Sbjct: 478 PLQVPPSPPASPPMSPSATPPPQ------------------------APPPLAAPPLQLA 513
Query: 165 QANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGT--PGSRSRTPSLPTPPTRE 222
+ P + PPA TPP P G +P SP P S TP PP
Sbjct: 514 KP-----PPQAPPALATPPLQALPSPPASFPG-QAPFSPSASLPMSPLATPPPQAPPVLA 567
Query: 223 PKKVAVVRTPPKSPSSAKSRLQTAPVPMPD 252
+ V +PP SP+ R P P PD
Sbjct: 568 APLLQVPPSPPASPTLQAPR--RPPTPGPD 595
Score = 42.7 bits (99), Expect = 7e-04
Identities = 50/179 (27%), Positives = 66/179 (36%), Gaps = 27/179 (15%)
Query: 85 PGKQAAAQPHTEIPE---GTTAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKK 141
P A +P TE P + +E + +P+ + R S+S + +
Sbjct: 192 PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATP-LS 250
Query: 142 AKGADGKTKIATPRGAAPPGQ---KGQANATRIPAKTPPAPKTPPSSG--------EPPK 190
+ G + TPR A P Q KG A R P TPP P+ G P
Sbjct: 251 SPARSGPSARGTPRAPAHPSQPKPKG-LQALRPPQVTPPRKDAAPALGPLSSSPLATPSP 309
Query: 191 SGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVP 249
S + P P TP S S T L TP + P SPS+ S LQT P P
Sbjct: 310 SAALQSQAPPTLPATPHSSSLTCQLATP----------LPLAPPSPSAPPS-LQTLPSP 357
Score = 39.7 bits (91), Expect = 0.006
Identities = 53/225 (23%), Positives = 79/225 (35%), Gaps = 35/225 (15%)
Query: 43 LKESPLQTPTEDGSEEPGSETSDAKSTPTAEDVT---------APLVDEGAPGKQAAAQP 93
L SPL TP+ + + + + +TP + +T AP P Q P
Sbjct: 299 LSSSPLATPSPSAALQSQAPPT-LPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSP 357
Query: 94 HTEIPEGTTAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIAT 153
P T +P+L+ T + + S + +A A +A
Sbjct: 358 PATPPSQATTSLG----SPTLQ------ATHSFLPSPPLSPLATPPPQAPPA-----LAL 402
Query: 154 PRGAAPPGQKGQANATRIPAKTPPAPKT-------PPSSGEPPKSGDRSGYSSPGSPGTP 206
P APP + + +P AP P S PP ++ +S P SP P
Sbjct: 403 PPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFS-PPPSPPVQAPFSPPASP--P 459
Query: 207 GSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMP 251
S S TP PP+ + V +PP SP + S P P
Sbjct: 460 VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPP 504
Score = 29.3 bits (64), Expect = 7.5
Identities = 34/123 (27%), Positives = 53/123 (43%), Gaps = 17/123 (13%)
Query: 142 AKGADGKTKIATPRG----AAPPGQKGQANATRIPAKTPPAPKT-PPSSGEPPKSGDRSG 196
A GA G+ +A G A P +A TR + P + PP+SG ++
Sbjct: 49 AAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKN 108
Query: 197 YSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRT---------PPKSPSSAKSRLQTA- 246
+SPG +PG S T + P P ++ +++ T P +S SA +R T+
Sbjct: 109 -TSPGPVSSPGRASGT-TRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSG 166
Query: 247 PVP 249
P P
Sbjct: 167 PTP 169
Score = 28.9 bits (63), Expect = 9.7
Identities = 54/226 (23%), Positives = 73/226 (32%), Gaps = 33/226 (14%)
Query: 41 AGLKESPLQTPTEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEI--P 98
A L SPL TP + +P A AP + P T + P
Sbjct: 548 ASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQ------APRRPPTPGPDTSVSGP 601
Query: 99 EGTTAEEAGIGDTPSLEDEA-------AGHVTQARMVSKSKDGTGSDDKKAKGA----DG 147
T A G PS + AGH + A + G S + A D
Sbjct: 602 RLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDA 661
Query: 148 KTKIATP----RGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPG-S 202
+ P RG APP A +P PP++G G + Y + G
Sbjct: 662 ELAACHPAAWSRGPAPPLAFRGAPGAPLP--------WPPATGPGSADGLCTIYETEGPE 713
Query: 203 PGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPV 248
TP + P P+P T K A S S ++RL P+
Sbjct: 714 SATPAPGALDPG-PSPGTSGGKAAAGAGAGASSRSPKQARLGELPL 758
Score = 28.9 bits (63), Expect = 9.7
Identities = 26/103 (25%), Positives = 34/103 (33%), Gaps = 6/103 (5%)
Query: 151 IATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRS 210
+ PR PG + R+ P P PP PP S S P G S +
Sbjct: 583 LQAPRRPPTPGPDTSVSGPRLTLALAPGP--PP----PPSRSPSSTLSGPDLAGHSSSAT 636
Query: 211 RTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDL 253
TP P+ A PP + +A + P P L
Sbjct: 637 STPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPL 679
>gi|31324577 molecule interacting with Rab13 [Homo sapiens]
Length = 863
Score = 49.7 bits (117), Expect = 5e-06
Identities = 67/284 (23%), Positives = 111/284 (39%), Gaps = 40/284 (14%)
Query: 29 YTMHQDQEGDTDAGLKESPLQTPTEDGSEEPGSETSDAKS-------TPTAEDVT----A 77
Y +++E D + +E+P P+ S G S KS TPT+ T A
Sbjct: 424 YNPFEEEEEDKE---EEAPA-APSLATSPALGHPESTPKSLHPWYGITPTSSPKTKKRPA 479
Query: 78 PLVDEGAP-GKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTG 136
P +P A+ H+E P T + + SL E+A A ++
Sbjct: 480 PRAPSASPLALHASRLSHSEPPSATPSPALSV---ESLSSESASQTAGAELLEPPAVPKS 536
Query: 137 SDDKK--AKGADGK-TKIATPRGAAPPGQKGQANATRIPAKTPP-APKTPPSSGEPPKS- 191
S + A G G ++T A G+ + ++P +P AP+T SSG P
Sbjct: 537 SSEPAVHAPGTPGNPVSLSTNSSLASSGELVEPRVEQMPQASPGLAPRTRGSSGPQPAKP 596
Query: 192 ------------GDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSA 239
GDRS SPGS +P + ++ P R+P A +P ++
Sbjct: 597 CSGATPTPLLLVGDRSPVPSPGS-SSPQLQVKSSCKENPFNRKPSPAA---SPATKKATK 652
Query: 240 KSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLD 283
S+ P P +K K+ + + + + G++ I ++LD
Sbjct: 653 GSKPVRPPAPGHGFPLIKRKVQADQYIPEEDIHGEMDTIERRLD 696
Score = 36.6 bits (83), Expect = 0.047
Identities = 33/125 (26%), Positives = 52/125 (41%), Gaps = 14/125 (11%)
Query: 159 PPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTP 218
P Q Q + ++ P PSS P +G + G +P +R P +PT
Sbjct: 233 PFSQPKQQHQQQLAEDAKDVPGGGPSSSAP------AGAEADGPKASPEAR---PQIPTK 283
Query: 219 PTREPKKVAVVRTPPKS-PSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQI 277
P R P K+ + +PP P+ A + + P P +S + ENL Q G +
Sbjct: 284 P-RVPGKLQELASPPAGRPTPAPRKASESTTPAPPTPRPRSSL-QQENLVEQAGSS--SL 339
Query: 278 INKKL 282
+N +L
Sbjct: 340 VNGRL 344
Score = 34.3 bits (77), Expect = 0.23
Identities = 56/251 (22%), Positives = 85/251 (33%), Gaps = 53/251 (21%)
Query: 48 LQTPTEDGSEEPGSETSDAKSTPT--------AEDVTAPLVDEGAPGKQAAAQPHTEIPE 99
L P G+ +P T + P + APL +PG + Q ++
Sbjct: 347 LPVPKPRGTPKPSEGTPAPRKDPPWITLVQAEPKKKPAPLPPSSSPGPPS--QDSRQVEN 404
Query: 100 GTTAEEAGIGDTPSLED-------------EAAGHVTQARMVSKSKDGTGSDDKKAKGAD 146
G T E A T SLE E + S + S K
Sbjct: 405 GGTEEVAQPSPTASLESKPYNPFEEEEEDKEEEAPAAPSLATSPALGHPESTPKSLHPWY 464
Query: 147 GKTKIATPRGAAPPGQKGQA------NATRIPAKTPPAPKTPPSSG-------------- 186
G T ++P+ P + + +A+R+ PP+ P+
Sbjct: 465 GITPTSSPKTKKRPAPRAPSASPLALHASRLSHSEPPSATPSPALSVESLSSESASQTAG 524
Query: 187 ----EPP---KSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSA 239
EPP KS +PG+PG P S S SL + + E + V + P SP A
Sbjct: 525 AELLEPPAVPKSSSEPAVHAPGTPGNPVSLSTNSSLAS--SGELVEPRVEQMPQASPGLA 582
Query: 240 -KSRLQTAPVP 249
++R + P P
Sbjct: 583 PRTRGSSGPQP 593
Score = 33.9 bits (76), Expect = 0.30
Identities = 32/106 (30%), Positives = 39/106 (36%), Gaps = 9/106 (8%)
Query: 147 GKTKIATPRGAAPPGQKGQANAT-RIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGT 205
G + P GA G K A +IP K P P PP +G +P
Sbjct: 255 GGPSSSAPAGAEADGPKASPEARPQIPTK-PRVPGKLQELASPP-----AGRPTPAP--R 306
Query: 206 PGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMP 251
S S TP+ PTP R + + S S RL PVP P
Sbjct: 307 KASESTTPAPPTPRPRSSLQQENLVEQAGSSSLVNGRLHELPVPKP 352
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.304 0.126 0.354
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,919,425
Number of Sequences: 37866
Number of extensions: 1380681
Number of successful extensions: 16813
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 340
Number of HSP's successfully gapped in prelim test: 1514
Number of HSP's that attempted gapping in prelim test: 7469
Number of HSP's gapped (non-prelim): 6533
length of query: 441
length of database: 18,247,518
effective HSP length: 105
effective length of query: 336
effective length of database: 14,271,588
effective search space: 4795253568
effective search space used: 4795253568
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.