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Search of human proteins with 66363686
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|66363686 NEDD8 activating enzyme E1 subunit 1 isoform b
[Homo sapiens]
(528 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|66363686 NEDD8 activating enzyme E1 subunit 1 isoform b [Homo... 1058 0.0
gi|4502169 NEDD8 activating enzyme E1 subunit 1 isoform a [Homo ... 1038 0.0
gi|66363688 NEDD8 activating enzyme E1 subunit 1 isoform c [Homo... 894 0.0
gi|7705473 SUMO1 activating enzyme subunit 1 isoform a [Homo sap... 93 7e-19
gi|225543288 SUMO1 activating enzyme subunit 1 isoform c [Homo s... 91 3e-18
gi|225543285 SUMO1 activating enzyme subunit 1 isoform b [Homo s... 91 3e-18
gi|4885585 SUMO1 activating enzyme subunit 1 isoform a [Homo sap... 91 3e-18
gi|23510338 ubiquitin-activating enzyme E1 [Homo sapiens] 71 2e-12
gi|23510340 ubiquitin-activating enzyme E1 [Homo sapiens] 71 2e-12
gi|38045948 ubiquitin-like modifier activating enzyme 7 [Homo sa... 60 6e-09
gi|150417996 ubiquitin-activating enzyme E1-like 2 [Homo sapiens] 59 8e-09
gi|4885649 SUMO-1 activating enzyme subunit 2 [Homo sapiens] 51 3e-06
gi|38045944 ubiquitin-activating enzyme 3 isoform 2 [Homo sapiens] 49 9e-06
gi|38045942 ubiquitin-activating enzyme 3 isoform 1 [Homo sapiens] 49 9e-06
gi|7657339 molybdenum cofactor synthesis 3 [Homo sapiens] 33 0.49
gi|71274148 pleckstrin homology domain containing, family G (wit... 32 1.4
gi|170763513 ATP/GTP binding protein 1 [Homo sapiens] 31 2.4
gi|38327032 ubiquitin-activating enzyme 5 isoform 2 [Homo sapiens] 31 3.2
gi|13376212 ubiquitin-activating enzyme 5 isoform 1 [Homo sapiens] 31 3.2
gi|111548666 SNF2 histone linker PHD RING helicase isoform a [Ho... 31 3.2
gi|27436873 SNF2 histone linker PHD RING helicase isoform b [Hom... 31 3.2
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens] 30 5.4
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens] 30 5.4
gi|21361724 nuclear transport factor 2-like export factor 2 [Hom... 30 5.4
gi|38373673 synaptonemal complex protein 2 [Homo sapiens] 30 5.4
gi|37594469 3-hydroxyisobutyryl-Coenzyme A hydrolase isoform 2 [... 30 7.1
gi|37594471 3-hydroxyisobutyryl-Coenzyme A hydrolase isoform 1 [... 30 7.1
gi|44890065 hypothetical protein LOC6936 [Homo sapiens] 29 9.3
gi|8923009 non-SMC element 4 homolog A [Homo sapiens] 29 9.3
>gi|66363686 NEDD8 activating enzyme E1 subunit 1 isoform b [Homo
sapiens]
Length = 528
Score = 1058 bits (2736), Expect = 0.0
Identities = 528/528 (100%), Positives = 528/528 (100%)
Query: 1 MDAQQTKTNEARLWGDHGQEALESAHVCLINATATGTEILKNLVLPGIGSFTIIDGNQVS 60
MDAQQTKTNEARLWGDHGQEALESAHVCLINATATGTEILKNLVLPGIGSFTIIDGNQVS
Sbjct: 1 MDAQQTKTNEARLWGDHGQEALESAHVCLINATATGTEILKNLVLPGIGSFTIIDGNQVS 60
Query: 61 GEDAGNNFFLQRSSIGKNRAEAAMEFLQELNSDVSGSFVEESPENLLDNDPSFFCRFTVV 120
GEDAGNNFFLQRSSIGKNRAEAAMEFLQELNSDVSGSFVEESPENLLDNDPSFFCRFTVV
Sbjct: 61 GEDAGNNFFLQRSSIGKNRAEAAMEFLQELNSDVSGSFVEESPENLLDNDPSFFCRFTVV 120
Query: 121 VATQLPESTSLRLADVLWNSQIPLLICRTYGLVGYMRIIIKEHPVIESHPDNALEDLRLD 180
VATQLPESTSLRLADVLWNSQIPLLICRTYGLVGYMRIIIKEHPVIESHPDNALEDLRLD
Sbjct: 121 VATQLPESTSLRLADVLWNSQIPLLICRTYGLVGYMRIIIKEHPVIESHPDNALEDLRLD 180
Query: 181 KPFPELREHFQSYDLDHMEKKDHSHTPWIVIIAKYLAQWYSETNGRIPKTYKEKEDFRDL 240
KPFPELREHFQSYDLDHMEKKDHSHTPWIVIIAKYLAQWYSETNGRIPKTYKEKEDFRDL
Sbjct: 181 KPFPELREHFQSYDLDHMEKKDHSHTPWIVIIAKYLAQWYSETNGRIPKTYKEKEDFRDL 240
Query: 241 IRQGILKNENGAPEDEENFEEAIKNVNTALNTTQIPSSIEDIFNDDRCINITKQTPSFWI 300
IRQGILKNENGAPEDEENFEEAIKNVNTALNTTQIPSSIEDIFNDDRCINITKQTPSFWI
Sbjct: 241 IRQGILKNENGAPEDEENFEEAIKNVNTALNTTQIPSSIEDIFNDDRCINITKQTPSFWI 300
Query: 301 LARALKEFVAKEGQGNLPVRGTIPDMIADSGKYIKLQNVYREKAKKDAAAVGNHVAKLLQ 360
LARALKEFVAKEGQGNLPVRGTIPDMIADSGKYIKLQNVYREKAKKDAAAVGNHVAKLLQ
Sbjct: 301 LARALKEFVAKEGQGNLPVRGTIPDMIADSGKYIKLQNVYREKAKKDAAAVGNHVAKLLQ 360
Query: 361 SIGQAPESISEKELKLLCSNSAFLRVVRCRSLAEEYGLDTINKDEIISSMDNPDNEIVLY 420
SIGQAPESISEKELKLLCSNSAFLRVVRCRSLAEEYGLDTINKDEIISSMDNPDNEIVLY
Sbjct: 361 SIGQAPESISEKELKLLCSNSAFLRVVRCRSLAEEYGLDTINKDEIISSMDNPDNEIVLY 420
Query: 421 LMLRAVDRFHKQQGRYPGVSNYQVEEDIGKLKSCLTGFLQEYGLSVMVKDDYVHEFCRYG 480
LMLRAVDRFHKQQGRYPGVSNYQVEEDIGKLKSCLTGFLQEYGLSVMVKDDYVHEFCRYG
Sbjct: 421 LMLRAVDRFHKQQGRYPGVSNYQVEEDIGKLKSCLTGFLQEYGLSVMVKDDYVHEFCRYG 480
Query: 481 AAEPHTIAAFLGGAAAQEVIKIITKQFVIFNNTYIYSGMSQTSATFQL 528
AAEPHTIAAFLGGAAAQEVIKIITKQFVIFNNTYIYSGMSQTSATFQL
Sbjct: 481 AAEPHTIAAFLGGAAAQEVIKIITKQFVIFNNTYIYSGMSQTSATFQL 528
>gi|4502169 NEDD8 activating enzyme E1 subunit 1 isoform a [Homo
sapiens]
Length = 534
Score = 1038 bits (2685), Expect = 0.0
Identities = 518/525 (98%), Positives = 520/525 (99%)
Query: 4 QQTKTNEARLWGDHGQEALESAHVCLINATATGTEILKNLVLPGIGSFTIIDGNQVSGED 63
+Q + RLWGDHGQEALESAHVCLINATATGTEILKNLVLPGIGSFTIIDGNQVSGED
Sbjct: 10 EQKYDRQLRLWGDHGQEALESAHVCLINATATGTEILKNLVLPGIGSFTIIDGNQVSGED 69
Query: 64 AGNNFFLQRSSIGKNRAEAAMEFLQELNSDVSGSFVEESPENLLDNDPSFFCRFTVVVAT 123
AGNNFFLQRSSIGKNRAEAAMEFLQELNSDVSGSFVEESPENLLDNDPSFFCRFTVVVAT
Sbjct: 70 AGNNFFLQRSSIGKNRAEAAMEFLQELNSDVSGSFVEESPENLLDNDPSFFCRFTVVVAT 129
Query: 124 QLPESTSLRLADVLWNSQIPLLICRTYGLVGYMRIIIKEHPVIESHPDNALEDLRLDKPF 183
QLPESTSLRLADVLWNSQIPLLICRTYGLVGYMRIIIKEHPVIESHPDNALEDLRLDKPF
Sbjct: 130 QLPESTSLRLADVLWNSQIPLLICRTYGLVGYMRIIIKEHPVIESHPDNALEDLRLDKPF 189
Query: 184 PELREHFQSYDLDHMEKKDHSHTPWIVIIAKYLAQWYSETNGRIPKTYKEKEDFRDLIRQ 243
PELREHFQSYDLDHMEKKDHSHTPWIVIIAKYLAQWYSETNGRIPKTYKEKEDFRDLIRQ
Sbjct: 190 PELREHFQSYDLDHMEKKDHSHTPWIVIIAKYLAQWYSETNGRIPKTYKEKEDFRDLIRQ 249
Query: 244 GILKNENGAPEDEENFEEAIKNVNTALNTTQIPSSIEDIFNDDRCINITKQTPSFWILAR 303
GILKNENGAPEDEENFEEAIKNVNTALNTTQIPSSIEDIFNDDRCINITKQTPSFWILAR
Sbjct: 250 GILKNENGAPEDEENFEEAIKNVNTALNTTQIPSSIEDIFNDDRCINITKQTPSFWILAR 309
Query: 304 ALKEFVAKEGQGNLPVRGTIPDMIADSGKYIKLQNVYREKAKKDAAAVGNHVAKLLQSIG 363
ALKEFVAKEGQGNLPVRGTIPDMIADSGKYIKLQNVYREKAKKDAAAVGNHVAKLLQSIG
Sbjct: 310 ALKEFVAKEGQGNLPVRGTIPDMIADSGKYIKLQNVYREKAKKDAAAVGNHVAKLLQSIG 369
Query: 364 QAPESISEKELKLLCSNSAFLRVVRCRSLAEEYGLDTINKDEIISSMDNPDNEIVLYLML 423
QAPESISEKELKLLCSNSAFLRVVRCRSLAEEYGLDTINKDEIISSMDNPDNEIVLYLML
Sbjct: 370 QAPESISEKELKLLCSNSAFLRVVRCRSLAEEYGLDTINKDEIISSMDNPDNEIVLYLML 429
Query: 424 RAVDRFHKQQGRYPGVSNYQVEEDIGKLKSCLTGFLQEYGLSVMVKDDYVHEFCRYGAAE 483
RAVDRFHKQQGRYPGVSNYQVEEDIGKLKSCLTGFLQEYGLSVMVKDDYVHEFCRYGAAE
Sbjct: 430 RAVDRFHKQQGRYPGVSNYQVEEDIGKLKSCLTGFLQEYGLSVMVKDDYVHEFCRYGAAE 489
Query: 484 PHTIAAFLGGAAAQEVIKIITKQFVIFNNTYIYSGMSQTSATFQL 528
PHTIAAFLGGAAAQEVIKIITKQFVIFNNTYIYSGMSQTSATFQL
Sbjct: 490 PHTIAAFLGGAAAQEVIKIITKQFVIFNNTYIYSGMSQTSATFQL 534
>gi|66363688 NEDD8 activating enzyme E1 subunit 1 isoform c [Homo
sapiens]
Length = 445
Score = 894 bits (2311), Expect = 0.0
Identities = 445/445 (100%), Positives = 445/445 (100%)
Query: 84 MEFLQELNSDVSGSFVEESPENLLDNDPSFFCRFTVVVATQLPESTSLRLADVLWNSQIP 143
MEFLQELNSDVSGSFVEESPENLLDNDPSFFCRFTVVVATQLPESTSLRLADVLWNSQIP
Sbjct: 1 MEFLQELNSDVSGSFVEESPENLLDNDPSFFCRFTVVVATQLPESTSLRLADVLWNSQIP 60
Query: 144 LLICRTYGLVGYMRIIIKEHPVIESHPDNALEDLRLDKPFPELREHFQSYDLDHMEKKDH 203
LLICRTYGLVGYMRIIIKEHPVIESHPDNALEDLRLDKPFPELREHFQSYDLDHMEKKDH
Sbjct: 61 LLICRTYGLVGYMRIIIKEHPVIESHPDNALEDLRLDKPFPELREHFQSYDLDHMEKKDH 120
Query: 204 SHTPWIVIIAKYLAQWYSETNGRIPKTYKEKEDFRDLIRQGILKNENGAPEDEENFEEAI 263
SHTPWIVIIAKYLAQWYSETNGRIPKTYKEKEDFRDLIRQGILKNENGAPEDEENFEEAI
Sbjct: 121 SHTPWIVIIAKYLAQWYSETNGRIPKTYKEKEDFRDLIRQGILKNENGAPEDEENFEEAI 180
Query: 264 KNVNTALNTTQIPSSIEDIFNDDRCINITKQTPSFWILARALKEFVAKEGQGNLPVRGTI 323
KNVNTALNTTQIPSSIEDIFNDDRCINITKQTPSFWILARALKEFVAKEGQGNLPVRGTI
Sbjct: 181 KNVNTALNTTQIPSSIEDIFNDDRCINITKQTPSFWILARALKEFVAKEGQGNLPVRGTI 240
Query: 324 PDMIADSGKYIKLQNVYREKAKKDAAAVGNHVAKLLQSIGQAPESISEKELKLLCSNSAF 383
PDMIADSGKYIKLQNVYREKAKKDAAAVGNHVAKLLQSIGQAPESISEKELKLLCSNSAF
Sbjct: 241 PDMIADSGKYIKLQNVYREKAKKDAAAVGNHVAKLLQSIGQAPESISEKELKLLCSNSAF 300
Query: 384 LRVVRCRSLAEEYGLDTINKDEIISSMDNPDNEIVLYLMLRAVDRFHKQQGRYPGVSNYQ 443
LRVVRCRSLAEEYGLDTINKDEIISSMDNPDNEIVLYLMLRAVDRFHKQQGRYPGVSNYQ
Sbjct: 301 LRVVRCRSLAEEYGLDTINKDEIISSMDNPDNEIVLYLMLRAVDRFHKQQGRYPGVSNYQ 360
Query: 444 VEEDIGKLKSCLTGFLQEYGLSVMVKDDYVHEFCRYGAAEPHTIAAFLGGAAAQEVIKII 503
VEEDIGKLKSCLTGFLQEYGLSVMVKDDYVHEFCRYGAAEPHTIAAFLGGAAAQEVIKII
Sbjct: 361 VEEDIGKLKSCLTGFLQEYGLSVMVKDDYVHEFCRYGAAEPHTIAAFLGGAAAQEVIKII 420
Query: 504 TKQFVIFNNTYIYSGMSQTSATFQL 528
TKQFVIFNNTYIYSGMSQTSATFQL
Sbjct: 421 TKQFVIFNNTYIYSGMSQTSATFQL 445
>gi|7705473 SUMO1 activating enzyme subunit 1 isoform a [Homo
sapiens]
Length = 346
Score = 92.8 bits (229), Expect = 7e-19
Identities = 53/164 (32%), Positives = 81/164 (49%), Gaps = 3/164 (1%)
Query: 10 EARLWGDHGQEALESAHVCLINATATGTEILKNLVLPGIGSFTIIDGNQVSGEDAGNNFF 69
+ RLWG Q+ L ++ V L+ G EI KNL+L G+ T++D QV+ ED G F
Sbjct: 22 QIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFL 81
Query: 70 LQRSSIGKNRAEAAMEFLQELNSDVSGSFVEESPENLLDNDPSFFCRFTVVVATQLPEST 129
++ S+G+NRAEA++E Q LN V V+ E++ SFF +F V T
Sbjct: 82 IRTGSVGRNRAEASLERAQNLNPMVD---VKVDTEDIEKKPESFFTQFDAVCLTCCSRDV 138
Query: 130 SLRLADVLWNSQIPLLICRTYGLVGYMRIIIKEHPVIESHPDNA 173
+++ + + I +G GY + EH +E D A
Sbjct: 139 IVKVDQICHKNSIKFFTGDAFGYHGYTFANLGEHEFVEEETDVA 182
Score = 47.4 bits (111), Expect = 3e-05
Identities = 30/100 (30%), Positives = 48/100 (48%), Gaps = 5/100 (5%)
Query: 420 YLMLRAVDRFHKQQGRYPGVSNYQVEEDIGKLKSCLTGFLQEYGLSVMVKDDYVHEFCRY 479
Y +L+ + +F +GR P Y EED L L G+S D +F RY
Sbjct: 240 YFLLQVLLKFRTDKGRDPSSDTY--EEDSELLLQIRNDVLDSLGIS---PDLLPEDFVRY 294
Query: 480 GAAEPHTIAAFLGGAAAQEVIKIITKQFVIFNNTYIYSGM 519
+E + A +GG AQE++K ++++ NN + + GM
Sbjct: 295 CFSEMAPVCAVVGGILAQEIVKALSQRDPPHNNFFFFDGM 334
>gi|225543288 SUMO1 activating enzyme subunit 1 isoform c [Homo
sapiens]
Length = 266
Score = 90.5 bits (223), Expect = 3e-18
Identities = 51/158 (32%), Positives = 79/158 (50%), Gaps = 3/158 (1%)
Query: 10 EARLWGDHGQEALESAHVCLINATATGTEILKNLVLPGIGSFTIIDGNQVSGEDAGNNFF 69
+ RLWG Q+ L ++ V L+ G EI KNL+L G+ T++D QV+ ED G F
Sbjct: 22 QIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFL 81
Query: 70 LQRSSIGKNRAEAAMEFLQELNSDVSGSFVEESPENLLDNDPSFFCRFTVVVATQLPEST 129
++ S+G+NRAEA++E Q LN V V+ E++ SFF +F V T
Sbjct: 82 IRTGSVGRNRAEASLERAQNLNPMVD---VKVDTEDIEKKPESFFTQFDAVCLTCCSRDV 138
Query: 130 SLRLADVLWNSQIPLLICRTYGLVGYMRIIIKEHPVIE 167
+++ + + I +G GY + EH +E
Sbjct: 139 IVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVE 176
>gi|225543285 SUMO1 activating enzyme subunit 1 isoform b [Homo
sapiens]
Length = 299
Score = 90.5 bits (223), Expect = 3e-18
Identities = 51/158 (32%), Positives = 79/158 (50%), Gaps = 3/158 (1%)
Query: 10 EARLWGDHGQEALESAHVCLINATATGTEILKNLVLPGIGSFTIIDGNQVSGEDAGNNFF 69
+ RLWG Q+ L ++ V L+ G EI KNL+L G+ T++D QV+ ED G F
Sbjct: 22 QIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFL 81
Query: 70 LQRSSIGKNRAEAAMEFLQELNSDVSGSFVEESPENLLDNDPSFFCRFTVVVATQLPEST 129
++ S+G+NRAEA++E Q LN V V+ E++ SFF +F V T
Sbjct: 82 IRTGSVGRNRAEASLERAQNLNPMVD---VKVDTEDIEKKPESFFTQFDAVCLTCCSRDV 138
Query: 130 SLRLADVLWNSQIPLLICRTYGLVGYMRIIIKEHPVIE 167
+++ + + I +G GY + EH +E
Sbjct: 139 IVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVE 176
>gi|4885585 SUMO1 activating enzyme subunit 1 isoform a [Homo
sapiens]
Length = 346
Score = 90.5 bits (223), Expect = 3e-18
Identities = 51/158 (32%), Positives = 79/158 (50%), Gaps = 3/158 (1%)
Query: 10 EARLWGDHGQEALESAHVCLINATATGTEILKNLVLPGIGSFTIIDGNQVSGEDAGNNFF 69
+ RLWG Q+ L ++ V L+ G EI KNL+L G+ T++D QV+ ED G F
Sbjct: 22 QIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFL 81
Query: 70 LQRSSIGKNRAEAAMEFLQELNSDVSGSFVEESPENLLDNDPSFFCRFTVVVATQLPEST 129
++ S+G+NRAEA++E Q LN V V+ E++ SFF +F V T
Sbjct: 82 IRTGSVGRNRAEASLERAQNLNPMVD---VKVDTEDIEKKPESFFTQFDAVCLTCCSRDV 138
Query: 130 SLRLADVLWNSQIPLLICRTYGLVGYMRIIIKEHPVIE 167
+++ + + I +G GY + EH +E
Sbjct: 139 IVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVE 176
Score = 48.1 bits (113), Expect = 2e-05
Identities = 44/167 (26%), Positives = 79/167 (47%), Gaps = 15/167 (8%)
Query: 355 VAKLLQSIGQAPESISEKELKLLCSNSAFLR--VVRCRSLAEEYGLDTINKDEIISSMDN 412
VAK+ Q + P++ K KL S + ++ VV C + E +D + ++ +++
Sbjct: 181 VAKVSQGVEDGPDT---KRAKLDSSETTMVKKKVVFC-PVKEALEVDW-SSEKAKAALKR 235
Query: 413 PDNEIVLYLMLRAVDRFHKQQGRYPGVSNYQVEEDIGKLKSCLTGFLQEYGLSVMVKDDY 472
++ Y +L+ + +F +GR P Y EED L L G+S D
Sbjct: 236 TTSD---YFLLQVLLKFRTDKGRDPSSDTY--EEDSELLLQIRNDVLDSLGIS---PDLL 287
Query: 473 VHEFCRYGAAEPHTIAAFLGGAAAQEVIKIITKQFVIFNNTYIYSGM 519
+F RY +E + A +GG AQE++K ++++ NN + + GM
Sbjct: 288 PEDFVRYCFSEMAPVCAVVGGILAQEIVKALSQRDPPHNNFFFFDGM 334
>gi|23510338 ubiquitin-activating enzyme E1 [Homo sapiens]
Length = 1058
Score = 71.2 bits (173), Expect = 2e-12
Identities = 47/147 (31%), Positives = 68/147 (46%), Gaps = 16/147 (10%)
Query: 15 GDHGQEALESAHVCLINATATGTEILKNLVLPGIGSFTIIDGNQVSGEDAGNNFFLQRSS 74
G + L+++ V + G EI KN++L G+ + T+ D D + F+L+
Sbjct: 63 GHEAMKRLQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQGTAQWADLSSQFYLREED 122
Query: 75 IGKNRAEAAMEFLQELNSDV-----SGSFVEESPENLLDNDPSFFCRFTVVVATQLPEST 129
IGKNRAE + L ELNS V +G VE+ F F VVV T P
Sbjct: 123 IGKNRAEVSQPRLAELNSYVPVTAYTGPLVED-----------FLSGFQVVVLTNTPLED 171
Query: 130 SLRLADVLWNSQIPLLICRTYGLVGYM 156
LR+ + N I L++ T GL G +
Sbjct: 172 QLRVGEFCHNRGIKLVVADTRGLFGQL 198
Score = 38.9 bits (89), Expect = 0.012
Identities = 42/220 (19%), Positives = 87/220 (39%), Gaps = 22/220 (10%)
Query: 306 KEFVAKEGQGNLPVRGTIPDMIADSGKYIKLQNVYREKAKKDAAAVGNHVAKLLQSIGQA 365
+E + + G P+ + + D+ + + R + + V +++ G
Sbjct: 204 EEMILTDSNGEQPLSAMVSMVTKDNPGVVTCLDEARHGFESGDFVSFSEVQGMVELNGNQ 263
Query: 366 PESISEKELKLL-------CSNSAFLRVVRCRSLAEEYGLDTINKDEIISSMDNPDNEIV 418
P E+K+L C S F +R +++ I+ +++S+ PD +
Sbjct: 264 P-----MEIKVLGPYTFSICDTSNFSDYIRGGIVSQVKVPKKISFKSLVASLAEPDFVVT 318
Query: 419 ----------LYLMLRAVDRFHKQQGRYPGVSNYQVEEDIGKLKSCLTGFLQEYGLSVMV 468
L++ +A+ +F Q GR P N + ++ L + +
Sbjct: 319 DFAKFSRPAQLHIGFQALHQFCAQHGRPPRPRNEEDAAELVALAQAVNARALPAVQQNNL 378
Query: 469 KDDYVHEFCRYGAAEPHTIAAFLGGAAAQEVIKIITKQFV 508
+D + + A + I AF+GG AAQEV+K + +F+
Sbjct: 379 DEDLIRKLAYVAAGDLAPINAFIGGLAAQEVMKACSGKFM 418
Score = 37.7 bits (86), Expect = 0.026
Identities = 43/212 (20%), Positives = 82/212 (38%), Gaps = 16/212 (7%)
Query: 1 MDAQQTKTNEARLWGDHGQEALESAHVCLINATATGTEILKNLVLPGI-----GSFTIID 55
+ Q + ++G QE L L+ A A G E+LKN + G+ G + D
Sbjct: 445 LQRQNRYDGQVAVFGSDLQEKLGKQKYFLVGAGAIGCELLKNFAMIGLGCGEGGEIIVTD 504
Query: 56 GNQVSGEDAGNNFFLQRSSIGKNRAEAAMEFLQELNSDV----SGSFVEESPENLLDNDP 111
+ + + F + + K +++ A ++++N + + V E + D+D
Sbjct: 505 MDTIEKSNLNRQFLFRPWDVTKLKSDTAAAAVRQMNPHIRVTSHQNRVGPDTERIYDDD- 563
Query: 112 SFFCRFTVVVATQLPESTSLRLADVLWNSQIPLLICRTYGLVGYMRIII----KEHPVIE 167
FF V + + + PLL T G G ++++I + + +
Sbjct: 564 -FFQNLDGVANALDNVDARMYMDRRCVYYRKPLLESGTLGTKGNVQVVIPFLTESYSSSQ 622
Query: 168 SHPDNALEDLRLDKPFPELREHFQSYDLDHME 199
P+ ++ L K FP EH + D E
Sbjct: 623 DPPEKSIPICTL-KNFPNAIEHTLQWARDEFE 653
>gi|23510340 ubiquitin-activating enzyme E1 [Homo sapiens]
Length = 1058
Score = 71.2 bits (173), Expect = 2e-12
Identities = 47/147 (31%), Positives = 68/147 (46%), Gaps = 16/147 (10%)
Query: 15 GDHGQEALESAHVCLINATATGTEILKNLVLPGIGSFTIIDGNQVSGEDAGNNFFLQRSS 74
G + L+++ V + G EI KN++L G+ + T+ D D + F+L+
Sbjct: 63 GHEAMKRLQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQGTAQWADLSSQFYLREED 122
Query: 75 IGKNRAEAAMEFLQELNSDV-----SGSFVEESPENLLDNDPSFFCRFTVVVATQLPEST 129
IGKNRAE + L ELNS V +G VE+ F F VVV T P
Sbjct: 123 IGKNRAEVSQPRLAELNSYVPVTAYTGPLVED-----------FLSGFQVVVLTNTPLED 171
Query: 130 SLRLADVLWNSQIPLLICRTYGLVGYM 156
LR+ + N I L++ T GL G +
Sbjct: 172 QLRVGEFCHNRGIKLVVADTRGLFGQL 198
Score = 38.9 bits (89), Expect = 0.012
Identities = 42/220 (19%), Positives = 87/220 (39%), Gaps = 22/220 (10%)
Query: 306 KEFVAKEGQGNLPVRGTIPDMIADSGKYIKLQNVYREKAKKDAAAVGNHVAKLLQSIGQA 365
+E + + G P+ + + D+ + + R + + V +++ G
Sbjct: 204 EEMILTDSNGEQPLSAMVSMVTKDNPGVVTCLDEARHGFESGDFVSFSEVQGMVELNGNQ 263
Query: 366 PESISEKELKLL-------CSNSAFLRVVRCRSLAEEYGLDTINKDEIISSMDNPDNEIV 418
P E+K+L C S F +R +++ I+ +++S+ PD +
Sbjct: 264 P-----MEIKVLGPYTFSICDTSNFSDYIRGGIVSQVKVPKKISFKSLVASLAEPDFVVT 318
Query: 419 ----------LYLMLRAVDRFHKQQGRYPGVSNYQVEEDIGKLKSCLTGFLQEYGLSVMV 468
L++ +A+ +F Q GR P N + ++ L + +
Sbjct: 319 DFAKFSRPAQLHIGFQALHQFCAQHGRPPRPRNEEDAAELVALAQAVNARALPAVQQNNL 378
Query: 469 KDDYVHEFCRYGAAEPHTIAAFLGGAAAQEVIKIITKQFV 508
+D + + A + I AF+GG AAQEV+K + +F+
Sbjct: 379 DEDLIRKLAYVAAGDLAPINAFIGGLAAQEVMKACSGKFM 418
Score = 37.7 bits (86), Expect = 0.026
Identities = 43/212 (20%), Positives = 82/212 (38%), Gaps = 16/212 (7%)
Query: 1 MDAQQTKTNEARLWGDHGQEALESAHVCLINATATGTEILKNLVLPGI-----GSFTIID 55
+ Q + ++G QE L L+ A A G E+LKN + G+ G + D
Sbjct: 445 LQRQNRYDGQVAVFGSDLQEKLGKQKYFLVGAGAIGCELLKNFAMIGLGCGEGGEIIVTD 504
Query: 56 GNQVSGEDAGNNFFLQRSSIGKNRAEAAMEFLQELNSDV----SGSFVEESPENLLDNDP 111
+ + + F + + K +++ A ++++N + + V E + D+D
Sbjct: 505 MDTIEKSNLNRQFLFRPWDVTKLKSDTAAAAVRQMNPHIRVTSHQNRVGPDTERIYDDD- 563
Query: 112 SFFCRFTVVVATQLPESTSLRLADVLWNSQIPLLICRTYGLVGYMRIII----KEHPVIE 167
FF V + + + PLL T G G ++++I + + +
Sbjct: 564 -FFQNLDGVANALDNVDARMYMDRRCVYYRKPLLESGTLGTKGNVQVVIPFLTESYSSSQ 622
Query: 168 SHPDNALEDLRLDKPFPELREHFQSYDLDHME 199
P+ ++ L K FP EH + D E
Sbjct: 623 DPPEKSIPICTL-KNFPNAIEHTLQWARDEFE 653
>gi|38045948 ubiquitin-like modifier activating enzyme 7 [Homo
sapiens]
Length = 1012
Score = 59.7 bits (143), Expect = 6e-09
Identities = 44/147 (29%), Positives = 64/147 (43%), Gaps = 16/147 (10%)
Query: 15 GDHGQEALESAHVCLINATATGTEILKNLVLPGIGSFTIIDGNQVSGEDAGNNFFLQRSS 74
G + ++ A V + G E+ KNLVL G+GS T+ D + D F L
Sbjct: 23 GSPAMQRIQGARVLVSGLQGLGAEVAKNLVLMGVGSLTLHDPHPTCWSDLAAQFLLSEQD 82
Query: 75 IGKNRAEAAMEFLQELNSDV-----SGSFVEESPENLLDNDPSFFCRFTVVVATQLPEST 129
+ ++RAEA+ E L +LN V +G E+ LLD F VVV T
Sbjct: 83 LERSRAEASQELLAQLNRAVQVVVHTGDITEDL---LLD--------FQVVVLTAAKLEE 131
Query: 130 SLRLADVLWNSQIPLLICRTYGLVGYM 156
L++ + + L T GLVG +
Sbjct: 132 QLKVGTLCHKHGVCFLAADTRGLVGQL 158
Score = 45.1 bits (105), Expect = 2e-04
Identities = 25/87 (28%), Positives = 42/87 (48%), Gaps = 5/87 (5%)
Query: 13 LWGDHGQEALESAHVCLINATATGTEILKNLVLPGIGS-----FTIIDGNQVSGEDAGNN 67
++G QE L H L+ A A G E+LK L G+G+ T++D + + +
Sbjct: 421 VFGAGFQEKLRRQHYLLVGAGAIGCELLKVFALVGLGAGNSGGLTVVDMDHIERSNLSRQ 480
Query: 68 FFLQRSSIGKNRAEAAMEFLQELNSDV 94
F + +G+ +AE A + LN D+
Sbjct: 481 FLFRSQDVGRPKAEVAAAAARGLNPDL 507
>gi|150417996 ubiquitin-activating enzyme E1-like 2 [Homo sapiens]
Length = 1052
Score = 59.3 bits (142), Expect = 8e-09
Identities = 44/131 (33%), Positives = 60/131 (45%), Gaps = 5/131 (3%)
Query: 15 GDHGQEALESAHVCLINATATGTEILKNLVLPGIGSFTIIDGNQVSGEDAGNNFFLQRSS 74
GD + + +HV L G EI KNLVL GI + TI D + D G NFFL
Sbjct: 52 GDTAMQKMAKSHVFLSGMGGLGLEIAKNLVLAGIKAVTIHDTEKCQAWDLGTNFFLSEDD 111
Query: 75 I--GKNRAEAAMEFLQELNSDVSGSFVEESPENLLDNDPSFFCRFTVVVATQLPESTSLR 132
+ +NRAEA ++ + ELN V S D SF ++ VV T++ +
Sbjct: 112 VVNKRNRAEAVLKHIAELNPYV--HVTSSSVPFNETTDLSFLDKYQCVVLTEMKLPLQKK 169
Query: 133 LADVLWNSQIP 143
+ D SQ P
Sbjct: 170 IND-FCRSQCP 179
Score = 48.1 bits (113), Expect = 2e-05
Identities = 30/102 (29%), Positives = 52/102 (50%), Gaps = 3/102 (2%)
Query: 406 IISSMDNPDNEIVLYLMLRAVDRFHKQQGRYPGVSNYQVEEDIGKLKSCLTGFLQEYGLS 465
+I NP+ + ++ + A+D+F ++ R P V Q E++ KL + ++ L+E
Sbjct: 312 LIVDFSNPEAPLEIHTAMLALDQFQEKYSRKPNVGCQQDSEELLKLATSISETLEE---K 368
Query: 466 VMVKDDYVHEFCRYGAAEPHTIAAFLGGAAAQEVIKIITKQF 507
V D VH +AA +GG A+QEV+K +T +F
Sbjct: 369 PDVNADIVHWLSWTAQGFLSPLAAAVGGVASQEVLKAVTGKF 410
Score = 45.8 bits (107), Expect = 1e-04
Identities = 49/205 (23%), Positives = 84/205 (40%), Gaps = 14/205 (6%)
Query: 15 GDHGQEALESAHVCLINATATGTEILKNLVLPGIGS------FTIIDGNQVSGEDAGNNF 68
GD + L++ ++ L+ A G E+LKN L G+G+ T+ D + + + F
Sbjct: 451 GDTLCQKLQNLNIFLVGCGAIGCEMLKNFALLGVGTSKEKGMITVTDPDLIEKSNLNRQF 510
Query: 69 FLQRSSIGKNRAEAAMEFLQELNSD--VSGSFVEESPENLLDNDPSFFCRFTVVVATQLP 126
+ I K ++ A + ++NS + + P + F+ + V++ T L
Sbjct: 511 LFRPHHIQKPKSYTAADATLKINSQIKIDAHLNKVCPTTETIYNDEFYTKQDVII-TALD 569
Query: 127 ESTSLRLADVLWNSQI-PLLICRTYGLVGYMRIIIKE-HPVIESHPDNALEDLRLD--KP 182
+ R D + + PLL T G G+ +I+ SH D E++ K
Sbjct: 570 NVEARRYVDSRCLANLRPLLDSGTMGTKGHTEVIVPHLTESYNSHRDPPEEEIPFCTLKS 629
Query: 183 FPELREHFQSYDLDHMEKKDHSHTP 207
FP EH + D E SH P
Sbjct: 630 FPAAIEHTIQWARDKFE-SSFSHKP 653
>gi|4885649 SUMO-1 activating enzyme subunit 2 [Homo sapiens]
Length = 640
Score = 50.8 bits (120), Expect = 3e-06
Identities = 35/142 (24%), Positives = 65/142 (45%), Gaps = 1/142 (0%)
Query: 20 EALESAHVCLINATATGTEILKNLVLPGIGSFTIIDGNQVSGEDAGNNFFLQRSSIGKNR 79
EA+ V ++ A G E+LKNLVL G +ID + + + F Q+ +G+++
Sbjct: 13 EAVAGGRVLVVGAGGIGCELLKNLVLTGFSHIDLIDLDTIDVSNLNRQFLFQKKHVGRSK 72
Query: 80 AEAAMEFLQELNSDVSGSFVEESPENLLDNDPSFFCRFTVVVATQLPESTSLRLADVLWN 139
A+ A E + + + +S N D + FF +F +V+ + + +
Sbjct: 73 AQVAKESVLQFYPKANIVAYHDSIMN-PDYNVEFFRQFILVMNALDNRAARNHVNRMCLA 131
Query: 140 SQIPLLICRTYGLVGYMRIIIK 161
+ +PL+ T G +G + I K
Sbjct: 132 ADVPLIESGTAGYLGQVTTIKK 153
>gi|38045944 ubiquitin-activating enzyme 3 isoform 2 [Homo sapiens]
Length = 449
Score = 49.3 bits (116), Expect = 9e-06
Identities = 31/103 (30%), Positives = 49/103 (47%), Gaps = 3/103 (2%)
Query: 19 QEALESAHVCLINATATGTEILKNLVLPGIGSFTIIDGNQVSGEDAGNNFFLQRSSIGKN 78
Q L++ V +I A G E+LKNL L G +ID + + + F + IG+
Sbjct: 50 QFLLDTCKVLVIGAGGLGCELLKNLALSGFRQIHVIDMDTIDVSNLNRQFLFRPKDIGRP 109
Query: 79 RAEAAMEFLQELNSDVSGSFVEESPENLLDNDPSFFCRFTVVV 121
+AE A EF LN V V + D + +F+ +F ++V
Sbjct: 110 KAEVAAEF---LNDRVPNCNVVPHFNKIQDFNDTFYRQFHIIV 149
>gi|38045942 ubiquitin-activating enzyme 3 isoform 1 [Homo sapiens]
Length = 463
Score = 49.3 bits (116), Expect = 9e-06
Identities = 31/103 (30%), Positives = 49/103 (47%), Gaps = 3/103 (2%)
Query: 19 QEALESAHVCLINATATGTEILKNLVLPGIGSFTIIDGNQVSGEDAGNNFFLQRSSIGKN 78
Q L++ V +I A G E+LKNL L G +ID + + + F + IG+
Sbjct: 64 QFLLDTCKVLVIGAGGLGCELLKNLALSGFRQIHVIDMDTIDVSNLNRQFLFRPKDIGRP 123
Query: 79 RAEAAMEFLQELNSDVSGSFVEESPENLLDNDPSFFCRFTVVV 121
+AE A EF LN V V + D + +F+ +F ++V
Sbjct: 124 KAEVAAEF---LNDRVPNCNVVPHFNKIQDFNDTFYRQFHIIV 163
>gi|7657339 molybdenum cofactor synthesis 3 [Homo sapiens]
Length = 460
Score = 33.5 bits (75), Expect = 0.49
Identities = 21/80 (26%), Positives = 36/80 (45%)
Query: 15 GDHGQEALESAHVCLINATATGTEILKNLVLPGIGSFTIIDGNQVSGEDAGNNFFLQRSS 74
G HGQ L +A V ++ G + + L G+G ++D + V + +
Sbjct: 73 GVHGQLRLGTACVLIVGCGGLGCPLAQYLAAAGVGRLGLVDYDVVEMSNLARQVLHGEAL 132
Query: 75 IGKNRAEAAMEFLQELNSDV 94
G+ +A +A L+ LNS V
Sbjct: 133 AGQAKAFSAAASLRRLNSAV 152
>gi|71274148 pleckstrin homology domain containing, family G (with
RhoGef domain) member 1 [Homo sapiens]
Length = 1385
Score = 32.0 bits (71), Expect = 1.4
Identities = 31/149 (20%), Positives = 64/149 (42%), Gaps = 26/149 (17%)
Query: 241 IRQGILKNENGAPE---DEENFEEAIKNVNTA-LNTTQIPSSIEDIFNDDRCINITKQTP 296
IRQ + + E DE++++ + + +++ LN+T++ C + T P
Sbjct: 538 IRQALFPSRRSPQENEDDEDDYQMFVPSFSSSDLNSTRL------------CEDSTSSRP 585
Query: 297 SFWILARALKEFVAKEGQGNLPVR--------GTIPDMIADSGKYIKLQNVYREKAKKDA 348
W + + E G+ VR T P I S + +LQN + + +++
Sbjct: 586 CSWHMGQM--ESTETSSSGHRIVRRASSAGESNTCPPEIGTSDRTRELQNSPKTEGQEEM 643
Query: 349 AAVGNHVAKLLQSIGQAPESISEKELKLL 377
G+ + + I ++IS ++LKL+
Sbjct: 644 TPFGSSIELTIDDIDHVYDNISYEDLKLM 672
>gi|170763513 ATP/GTP binding protein 1 [Homo sapiens]
Length = 1186
Score = 31.2 bits (69), Expect = 2.4
Identities = 27/116 (23%), Positives = 47/116 (40%), Gaps = 15/116 (12%)
Query: 167 ESHPDNALEDLRL-DKPFPELREHFQSYDLDHMEKKDHSHTPWI--VIIAKYLAQWYSET 223
+ P +EDL++ + FPEL + FQ YDL E K + I+ + S
Sbjct: 369 QQEPGRTIEDLKMYEHLFPELVDDFQDYDLISKEPKPFVFEGKVRGPIVVPTAGEETSGN 428
Query: 224 NGRIPKTY------------KEKEDFRDLIRQGILKNENGAPEDEENFEEAIKNVN 267
+G + K ++K F DL ++ I N+ + + I +V+
Sbjct: 429 SGNLRKVVMKENISSKGDEGEKKSTFMDLAKEDIKDNDRTLQQQPGDQNRTISSVH 484
>gi|38327032 ubiquitin-activating enzyme 5 isoform 2 [Homo
sapiens]
Length = 348
Score = 30.8 bits (68), Expect = 3.2
Identities = 19/75 (25%), Positives = 34/75 (45%), Gaps = 1/75 (1%)
Query: 20 EALESAHVCLINATATGTEILKNLVLPGIGSFTIIDGNQVSGEDAGNNFFLQRSSIGKNR 79
E + + V ++ G+ + L GIG + D ++V + N F Q G ++
Sbjct: 13 EKIRTFAVAIVGVGGVGSVTAEMLTRCGIGKLLLFDYDKVELANM-NRLFFQPHQAGLSK 71
Query: 80 AEAAMEFLQELNSDV 94
+AA L+ +N DV
Sbjct: 72 VQAAEHTLRNINPDV 86
>gi|13376212 ubiquitin-activating enzyme 5 isoform 1 [Homo sapiens]
Length = 404
Score = 30.8 bits (68), Expect = 3.2
Identities = 19/75 (25%), Positives = 34/75 (45%), Gaps = 1/75 (1%)
Query: 20 EALESAHVCLINATATGTEILKNLVLPGIGSFTIIDGNQVSGEDAGNNFFLQRSSIGKNR 79
E + + V ++ G+ + L GIG + D ++V + N F Q G ++
Sbjct: 69 EKIRTFAVAIVGVGGVGSVTAEMLTRCGIGKLLLFDYDKVELANM-NRLFFQPHQAGLSK 127
Query: 80 AEAAMEFLQELNSDV 94
+AA L+ +N DV
Sbjct: 128 VQAAEHTLRNINPDV 142
>gi|111548666 SNF2 histone linker PHD RING helicase isoform a [Homo
sapiens]
Length = 1687
Score = 30.8 bits (68), Expect = 3.2
Identities = 20/78 (25%), Positives = 33/78 (42%), Gaps = 21/78 (26%)
Query: 148 RTYGLVGYMRIIIKEHPVIESHPDNALEDLRLDKPFPELREHFQS--------------- 192
R + M ++I HP I L D RL++ +LREH+ S
Sbjct: 1077 RLHATHNLMELLIARHPGIPP----TLRDGRLEEEAKQLREHYMSKCNTEVAEAQQALYP 1132
Query: 193 --YDLDHMEKKDHSHTPW 208
+ +++K HS++PW
Sbjct: 1133 VQQTIHELQRKIHSNSPW 1150
>gi|27436873 SNF2 histone linker PHD RING helicase isoform b [Homo
sapiens]
Length = 1659
Score = 30.8 bits (68), Expect = 3.2
Identities = 20/78 (25%), Positives = 33/78 (42%), Gaps = 21/78 (26%)
Query: 148 RTYGLVGYMRIIIKEHPVIESHPDNALEDLRLDKPFPELREHFQS--------------- 192
R + M ++I HP I L D RL++ +LREH+ S
Sbjct: 1077 RLHATHNLMELLIARHPGIPP----TLRDGRLEEEAKQLREHYMSKCNTEVAEAQQALYP 1132
Query: 193 --YDLDHMEKKDHSHTPW 208
+ +++K HS++PW
Sbjct: 1133 VQQTIHELQRKIHSNSPW 1150
>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
Length = 3907
Score = 30.0 bits (66), Expect = 5.4
Identities = 13/42 (30%), Positives = 23/42 (54%)
Query: 229 KTYKEKEDFRDLIRQGILKNENGAPEDEENFEEAIKNVNTAL 270
+ Y+E + +L+RQ ++ ED+E +E IK +N L
Sbjct: 1596 RQYQEHQQATELLRQAHMRQMERQREDQEQLQEEIKRLNRQL 1637
>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
Length = 3899
Score = 30.0 bits (66), Expect = 5.4
Identities = 13/42 (30%), Positives = 23/42 (54%)
Query: 229 KTYKEKEDFRDLIRQGILKNENGAPEDEENFEEAIKNVNTAL 270
+ Y+E + +L+RQ ++ ED+E +E IK +N L
Sbjct: 1596 RQYQEHQQATELLRQAHMRQMERQREDQEQLQEEIKRLNRQL 1637
>gi|21361724 nuclear transport factor 2-like export factor 2 [Homo
sapiens]
Length = 197
Score = 30.0 bits (66), Expect = 5.4
Identities = 25/84 (29%), Positives = 34/84 (40%), Gaps = 2/84 (2%)
Query: 53 IIDGNQVSGEDAGNNFF--LQRSSIGKNRAEAAMEFLQELNSDVSGSFVEESPENLLDND 110
I +GN VSG DA NNFF L S N + Q S + V N
Sbjct: 102 IWNGNAVSGLDALNNFFDTLPSSEFQVNMLDCQPVHEQATQSQTTVLVVTSGTVKFDGNK 161
Query: 111 PSFFCRFTVVVATQLPESTSLRLA 134
FF + ++ A P +T ++A
Sbjct: 162 QHFFNQNFLLTAQSTPNNTVWKIA 185
>gi|38373673 synaptonemal complex protein 2 [Homo sapiens]
Length = 1530
Score = 30.0 bits (66), Expect = 5.4
Identities = 21/99 (21%), Positives = 44/99 (44%), Gaps = 5/99 (5%)
Query: 212 IAKYLAQWYSETNGRIP-KTYKEKEDFRDLIRQGILKNENGAPEDEENFEEAIKNVNTAL 270
I K + + E R+P K K K++++DL + + +EN +N+++ +
Sbjct: 999 ITKKMDKTIPEGRIRLPRKATKTKKNYKDLSNSESECEQEFSHSFKENIPVKEENIHSRM 1058
Query: 271 NTTQIPSSIEDIFNDDRCINITKQTPSFWILARALKEFV 309
T ++P + +F C K+ W + LK+ +
Sbjct: 1059 KTVKLPKKQQKVF----CAETEKELSKQWKNSSLLKDAI 1093
>gi|37594469 3-hydroxyisobutyryl-Coenzyme A hydrolase isoform 2
[Homo sapiens]
Length = 338
Score = 29.6 bits (65), Expect = 7.1
Identities = 19/68 (27%), Positives = 32/68 (47%)
Query: 73 SSIGKNRAEAAMEFLQELNSDVSGSFVEESPENLLDNDPSFFCRFTVVVATQLPESTSLR 132
S I ++++ E + ++NS S + VEE ENL + SF V+ P S +
Sbjct: 251 SKIDRDKSFILEEHMDKINSCFSANTVEEIIENLQQDGSSFALEQLKVINKMSPTSLKIT 310
Query: 133 LADVLWNS 140
L ++ S
Sbjct: 311 LRQLMEGS 318
>gi|37594471 3-hydroxyisobutyryl-Coenzyme A hydrolase isoform 1
[Homo sapiens]
Length = 386
Score = 29.6 bits (65), Expect = 7.1
Identities = 19/68 (27%), Positives = 32/68 (47%)
Query: 73 SSIGKNRAEAAMEFLQELNSDVSGSFVEESPENLLDNDPSFFCRFTVVVATQLPESTSLR 132
S I ++++ E + ++NS S + VEE ENL + SF V+ P S +
Sbjct: 251 SKIDRDKSFILEEHMDKINSCFSANTVEEIIENLQQDGSSFALEQLKVINKMSPTSLKIT 310
Query: 133 LADVLWNS 140
L ++ S
Sbjct: 311 LRQLMEGS 318
>gi|44890065 hypothetical protein LOC6936 [Homo sapiens]
Length = 781
Score = 29.3 bits (64), Expect = 9.3
Identities = 16/59 (27%), Positives = 30/59 (50%), Gaps = 5/59 (8%)
Query: 119 VVVATQLPESTSLRLADVLWNSQIPLLICRTYGLVGYMRIIIKEHPVIESHPDNALEDL 177
++ T +P T + LW+ PL +T L+ + R+I++EH E+ + +DL
Sbjct: 553 IINKTIIPRLTDF--VEFLWD---PLSTSQTTSLITHCRVILEEHSTCENEVSKSRQDL 606
>gi|8923009 non-SMC element 4 homolog A [Homo sapiens]
Length = 385
Score = 29.3 bits (64), Expect = 9.3
Identities = 19/82 (23%), Positives = 37/82 (45%), Gaps = 6/82 (7%)
Query: 339 VYREKAKKDAAAVGNHVAKLLQSIGQAPESISEKELKLLCSNSAFLRVVRCRSLAEEYGL 398
++ E ++ A + H L +G EK +L S+F + +L G+
Sbjct: 120 LFNEVSRAREAVLDAHFLVLASDLG------IEKAKQLRSDLSSFDMLRYVETLLTHMGV 173
Query: 399 DTINKDEIISSMDNPDNEIVLY 420
+ + +E+I D+PD E ++Y
Sbjct: 174 NPLEAEELIRDEDSPDFEFIVY 195
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.134 0.389
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,361,721
Number of Sequences: 37866
Number of extensions: 865388
Number of successful extensions: 1911
Number of sequences better than 10.0: 29
Number of HSP's better than 10.0 without gapping: 19
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 1868
Number of HSP's gapped (non-prelim): 44
length of query: 528
length of database: 18,247,518
effective HSP length: 107
effective length of query: 421
effective length of database: 14,195,856
effective search space: 5976455376
effective search space used: 5976455376
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.