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Search of human proteins with 61743963
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|61743963 chromobox homolog 2 isoform 1 [Homo sapiens]
(532 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|61743963 chromobox homolog 2 isoform 1 [Homo sapiens] 1055 0.0
gi|14249190 chromobox homolog 2 isoform 2 [Homo sapiens] 197 2e-50
gi|55770830 chromobox homolog 4 [Homo sapiens] 129 5e-30
gi|10190682 chromobox homolog 8 [Homo sapiens] 124 2e-28
gi|46852392 chromobox homolog 6 [Homo sapiens] 114 2e-25
gi|28372505 chromobox homolog 7 [Homo sapiens] 102 1e-21
gi|188035910 heterochromatin protein 1-alpha [Homo sapiens] 72 2e-12
gi|188035908 heterochromatin protein 1-alpha [Homo sapiens] 72 2e-12
gi|6912292 heterochromatin protein 1-alpha [Homo sapiens] 72 2e-12
gi|5803076 heterochromatin protein 1-beta [Homo sapiens] 67 5e-11
gi|187960037 heterochromatin protein 1-beta [Homo sapiens] 67 5e-11
gi|41055989 M-phase phosphoprotein 8 [Homo sapiens] 65 2e-10
gi|15082258 chromobox homolog 3 [Homo sapiens] 63 6e-10
gi|20544151 chromobox homolog 3 [Homo sapiens] 63 6e-10
gi|92859678 small nuclear RNA activating complex, polypeptide 4,... 60 4e-09
gi|27734775 hypothetical protein LOC286499 [Homo sapiens] 56 7e-08
gi|221307494 chromodomain protein, Y chromosome-like isoform a [... 55 2e-07
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 53 6e-07
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 52 1e-06
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 52 2e-06
gi|116235487 chromodomain protein, Y-like 2 [Homo sapiens] 51 3e-06
gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens] 50 4e-06
gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens] 50 4e-06
gi|210032509 hypothetical protein LOC100130302 [Homo sapiens] 50 5e-06
gi|110832843 TBP-associated factor 4 [Homo sapiens] 49 1e-05
gi|48255931 hepatoma-derived growth factor-related protein 2 iso... 49 1e-05
gi|14249158 hepatoma-derived growth factor-related protein 2 iso... 49 1e-05
gi|4507869 vasodilator-stimulated phosphoprotein [Homo sapiens] 48 3e-05
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 48 3e-05
gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ... 48 3e-05
>gi|61743963 chromobox homolog 2 isoform 1 [Homo sapiens]
Length = 532
Score = 1055 bits (2729), Expect = 0.0
Identities = 532/532 (100%), Positives = 532/532 (100%)
Query: 1 MEELSSVGEQVFAAECILSKRLRKGKLEYLVKWRGWSSKHNSWEPEENILDPRLLLAFQK 60
MEELSSVGEQVFAAECILSKRLRKGKLEYLVKWRGWSSKHNSWEPEENILDPRLLLAFQK
Sbjct: 1 MEELSSVGEQVFAAECILSKRLRKGKLEYLVKWRGWSSKHNSWEPEENILDPRLLLAFQK 60
Query: 61 KEHEKEVQNRKRGKRPRGRPRKLTAMSSCSRRSKLKEPDAPSKSKSSSSSSSSTSSSSSS 120
KEHEKEVQNRKRGKRPRGRPRKLTAMSSCSRRSKLKEPDAPSKSKSSSSSSSSTSSSSSS
Sbjct: 61 KEHEKEVQNRKRGKRPRGRPRKLTAMSSCSRRSKLKEPDAPSKSKSSSSSSSSTSSSSSS 120
Query: 121 DEEDDSDLDAKRGPRGRETHPVPQKKAQILVAKPELKDPIRKKRGRKPLPPEQKATRRPV 180
DEEDDSDLDAKRGPRGRETHPVPQKKAQILVAKPELKDPIRKKRGRKPLPPEQKATRRPV
Sbjct: 121 DEEDDSDLDAKRGPRGRETHPVPQKKAQILVAKPELKDPIRKKRGRKPLPPEQKATRRPV 180
Query: 181 SLAKVLKTARKDLGAPASKLPPPLSAPVAGLAALKAHAKEACGGPSAMATPENLASLMKG 240
SLAKVLKTARKDLGAPASKLPPPLSAPVAGLAALKAHAKEACGGPSAMATPENLASLMKG
Sbjct: 181 SLAKVLKTARKDLGAPASKLPPPLSAPVAGLAALKAHAKEACGGPSAMATPENLASLMKG 240
Query: 241 MASSPGRGGISWQSSIVHYMNRMTQSQAQAASRLALKAQATNKCGLGLDLKVRTQKGELG 300
MASSPGRGGISWQSSIVHYMNRMTQSQAQAASRLALKAQATNKCGLGLDLKVRTQKGELG
Sbjct: 241 MASSPGRGGISWQSSIVHYMNRMTQSQAQAASRLALKAQATNKCGLGLDLKVRTQKGELG 300
Query: 301 MSPPGSKIPKAPSGGAVEQKVGNTGGPPHTHGASRVPAGCPGPQPAPTQELSLQVLDLQS 360
MSPPGSKIPKAPSGGAVEQKVGNTGGPPHTHGASRVPAGCPGPQPAPTQELSLQVLDLQS
Sbjct: 301 MSPPGSKIPKAPSGGAVEQKVGNTGGPPHTHGASRVPAGCPGPQPAPTQELSLQVLDLQS 360
Query: 361 VKNGMPGVGLLARHATATKGVPATNPAPGKGTGSGLIGASGATMPTDTSKSEKLASRAVA 420
VKNGMPGVGLLARHATATKGVPATNPAPGKGTGSGLIGASGATMPTDTSKSEKLASRAVA
Sbjct: 361 VKNGMPGVGLLARHATATKGVPATNPAPGKGTGSGLIGASGATMPTDTSKSEKLASRAVA 420
Query: 421 PPTPASKRDCVKGSATPSGQESRTAPGEARKAATLPEMSAGEESSSSDSDPDSASPPSTG 480
PPTPASKRDCVKGSATPSGQESRTAPGEARKAATLPEMSAGEESSSSDSDPDSASPPSTG
Sbjct: 421 PPTPASKRDCVKGSATPSGQESRTAPGEARKAATLPEMSAGEESSSSDSDPDSASPPSTG 480
Query: 481 QNPSVSVQTSQDWKPTRSLIEHVFVTDVTANLITVTVKESPTSVGFFNLRHY 532
QNPSVSVQTSQDWKPTRSLIEHVFVTDVTANLITVTVKESPTSVGFFNLRHY
Sbjct: 481 QNPSVSVQTSQDWKPTRSLIEHVFVTDVTANLITVTVKESPTSVGFFNLRHY 532
>gi|14249190 chromobox homolog 2 isoform 2 [Homo sapiens]
Length = 211
Score = 197 bits (502), Expect = 2e-50
Identities = 96/96 (100%), Positives = 96/96 (100%)
Query: 1 MEELSSVGEQVFAAECILSKRLRKGKLEYLVKWRGWSSKHNSWEPEENILDPRLLLAFQK 60
MEELSSVGEQVFAAECILSKRLRKGKLEYLVKWRGWSSKHNSWEPEENILDPRLLLAFQK
Sbjct: 1 MEELSSVGEQVFAAECILSKRLRKGKLEYLVKWRGWSSKHNSWEPEENILDPRLLLAFQK 60
Query: 61 KEHEKEVQNRKRGKRPRGRPRKLTAMSSCSRRSKLK 96
KEHEKEVQNRKRGKRPRGRPRKLTAMSSCSRRSKLK
Sbjct: 61 KEHEKEVQNRKRGKRPRGRPRKLTAMSSCSRRSKLK 96
>gi|55770830 chromobox homolog 4 [Homo sapiens]
Length = 560
Score = 129 bits (325), Expect = 5e-30
Identities = 169/599 (28%), Positives = 243/599 (40%), Gaps = 120/599 (20%)
Query: 3 ELSSVGEQVFAAECILSKRLRKGKLEYLVKWRGWSSKHNSWEPEENILDPRLLLAFQKKE 62
EL +VGE VFA E I KR+RKG++EYLVKWRGWS K+N+WEPEENILDPRLL+AFQ +E
Sbjct: 2 ELPAVGEHVFAVESIEKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILDPRLLIAFQNRE 61
Query: 63 HEKEVQN-RKRGKRPR----------GRPRKLTAM--SSCSRRSKLKEPDAPSKSKSSSS 109
++++ RKRG +P+ R LT + SS R+KL D ++ K
Sbjct: 62 RQEQLMGYRKRGPKPKPLVVQVPTFARRSNVLTGLQDSSTDNRAKL---DLGAQGKGQGH 118
Query: 110 SSSSTSSSSSSDEEDDSDLDAKRGPRGRE---THPVPQKKAQILVAKPELKDPIRKKRGR 166
S + + K P G+ + + KK P++ D ++ + G
Sbjct: 119 QYELNSKKHHQYQPHSKERAGKPPPPGKSGKYYYQLNSKKHHPYQPDPKMYD-LQYQGGH 177
Query: 167 KPLPPEQKATRRPVSLAKVLKTARKDLGAPASKLPPPLSAPVAG----LAALK--AHAKE 220
K P DLGA + PP A AG L A+K A A
Sbjct: 178 KEAP----------------SPTCPDLGAKSH--PPDKWAQGAGAKGYLGAVKPLAGAAG 219
Query: 221 ACGGPSAMATPENLASLMKGMASSPGRGGISWQSSIVHYMNRMTQSQAQAASRLALKAQA 280
A G S P + K + G GG + IV N+ + + + QA
Sbjct: 220 APGKGSEKGPPNGMMPAPKEAVTGNGIGG---KMKIVKNKNKNGRIVIVMSKYMENGMQA 276
Query: 281 TN-KCGLGLDLKVRT----QKGELGMSPPGSKIPKAPSGGAVEQKVGNTGGPPHTHGASR 335
K G + + R+ ++ PP + K + GA E+KV PP
Sbjct: 277 VKIKSGEVAEGEARSPSHKKRAADERHPPADRTFK-KAAGAEEKKV---EAPPKRREEEV 332
Query: 336 VPAGCPGPQPAPTQELS-------LQVLDLQSVKNGMPGVGLLARHATATKGVPATNPAP 388
P PQ A +++LS Q L L + + LLA P+ +P P
Sbjct: 333 SGVSDPQPQDAGSRKLSPTKEAFGEQPLQLTTKPD------LLAWDPARNTHPPSHHPHP 386
Query: 389 ------------GKGTGSGLIGASGATMPTDTSKSE----KLASRAVAPPT-----PASK 427
G L + + E +L +R+++ PT PA++
Sbjct: 387 HPHHHHHHHHHHHHAVGLNLSHVRKRCLSETHGEREPCKKRLTARSISTPTCLGGSPAAE 446
Query: 428 R--DCVKGSATPSGQ-----ESRTAPGEARKAATLPEMSAGEESSSSDSDPD-------- 472
R D +A P + P + R T E AGE SS P+
Sbjct: 447 RPADLPPAAALPQPEVILLDSDLDEPIDLRCVKTRSE--AGEPPSSLQVKPETPASAAVA 504
Query: 473 ---SASPPSTGQNPSVSVQTSQDWKPTRSLIE------HVFVTDVTANLITVTVKESPT 522
+A+P +T + P Q +P SL E ++ +TDVTAN +TVT KE T
Sbjct: 505 VAAAAAPTTTAEKPPAEAQD----EPAESLSEFKPFFGNIIITDVTANCLTVTFKEYVT 559
>gi|10190682 chromobox homolog 8 [Homo sapiens]
Length = 389
Score = 124 bits (311), Expect = 2e-28
Identities = 112/376 (29%), Positives = 162/376 (43%), Gaps = 96/376 (25%)
Query: 3 ELSSVGEQVFAAECILSKRLRKGKLEYLVKWRGWSSKHNSWEPEENILDPRLLLAFQKKE 62
ELS+VGE+VFAAE +L +R+RKG++EYLVKW+GWS K+++WEPEENILD RLL AF+++E
Sbjct: 2 ELSAVGERVFAAEALLKRRIRKGRMEYLVKWKGWSQKYSTWEPEENILDARLLAAFEERE 61
Query: 63 HEKEVQN-RKRGKRP---------RGRPRKLTAMSSCSRRSKLKEP-----DAPSKSK-- 105
E E+ +KRG +P + + + S +R ++ P D S S+
Sbjct: 62 REMELYGPKKRGPKPKTFLLKAQAKAKAKTYEFRSDSARGIRIPYPGRSPQDLASTSRAR 121
Query: 106 ------------SSSSSSSSTSSSSSSDEEDDSDLDAKRG-------PRGRETHPVPQKK 146
SS+S+SS+ + + D + D D D +R R RE ++
Sbjct: 122 EGLRNMGLSPPASSTSTSSTCRAEAPRDRDRDRDRDRERDRERERERERERERERERERG 181
Query: 147 AQILVAKPELKDPIRKKRGRKPLPPEQKATRRPVSLAKVLKTARKDLGAPASKLPPPLSA 206
+ KP KKRG KP RK+L P+ + PL
Sbjct: 182 TSRVDDKPSSPGDSSKKRGPKP---------------------RKELPDPSQR---PLGE 217
Query: 207 PVAGLAALKAHAKEACGGPSAMATPENLASLMKGMASSPGRGGISWQSSIVHYMNRMTQS 266
P AGL E G TP G G S++ R
Sbjct: 218 PSAGLG-------EYLKGRKLDDTPS-------------GAGKFPAGHSVIQLARRQDSD 257
Query: 267 QAQAASRLALKAQATNKCGLGLD------LKVRT----QKGELGMSPPGSKIPKA----P 312
Q A+AT K L +D +K R KG+ + P G+++
Sbjct: 258 LVQCGVTSPSSAEATGK--LAVDTFPARVIKHRAAFLEAKGQGALDPNGTRVRHGSGPPS 315
Query: 313 SGGAVEQKVGNTGGPP 328
SGG + + +G GG P
Sbjct: 316 SGGGLYRDMGAQGGRP 331
Score = 46.6 bits (109), Expect = 6e-05
Identities = 20/37 (54%), Positives = 27/37 (72%)
Query: 491 QDWKPTRSLIEHVFVTDVTANLITVTVKESPTSVGFF 527
+ W P+ + +E V VTDVT+N +TVT+KES T GFF
Sbjct: 349 ESWSPSLTNLEKVVVTDVTSNFLTVTIKESNTDQGFF 385
>gi|46852392 chromobox homolog 6 [Homo sapiens]
Length = 412
Score = 114 bits (286), Expect = 2e-25
Identities = 76/194 (39%), Positives = 109/194 (56%), Gaps = 17/194 (8%)
Query: 3 ELSSVGEQVFAAECILSKRLRKGKLEYLVKWRGWSSKHNSWEPEENILDPRLLLAFQKKE 62
ELS+VGE+VFAAE I+ +R+RKG++EYLVKW+GW+ K+++WEPEENILD RL+ AF++KE
Sbjct: 2 ELSAVGERVFAAESIIKRRIRKGRIEYLVKWKGWAIKYSTWEPEENILDSRLIAAFEQKE 61
Query: 63 HEKEVQN-RKRGKRPRGRPRKLTAMSSCSRRSKLKEPDAPSKSKSSSSSSSSTSSSSSSD 121
E+E+ +KRG +P+ K A + R S D K S+S+SS SS++
Sbjct: 62 RERELYGPKKRGPKPKTFLLKARAQAEALRIS-----DVHFSVKPSASASSPKLHSSAAV 116
Query: 122 EEDDSDLDAKRGPRGRETHPVPQKKAQILVAKPELKDPIR------KKRGRKPLPPEQKA 175
D+ R P+P+ Q P L+ PI + RK P E K
Sbjct: 117 HRLKKDI---RRCHRMSRRPLPRPDPQ--GGSPGLRPPISPFSETVRIINRKVKPREPKR 171
Query: 176 TRRPVSLAKVLKTA 189
R ++L + K A
Sbjct: 172 NRIILNLKVIDKGA 185
Score = 57.4 bits (137), Expect = 3e-08
Identities = 79/291 (27%), Positives = 106/291 (36%), Gaps = 64/291 (21%)
Query: 244 SPG-RGGISWQSSIVHYMNRMTQSQAQAASRLALKAQATNKCGLGLDLKVRTQKGELGMS 302
SPG R IS S V +NR + + +R+ L + +K G G G
Sbjct: 143 SPGLRPPISPFSETVRIINRKVKPREPKRNRIILNLKVIDKGAGG---------GGAGQG 193
Query: 303 PPGSKIPKAPSGGAV-------EQKVGNTGGPPHTHGASRVPAGCPGPQPAPTQELSLQV 355
PK PS V + V T GA + P P AP+
Sbjct: 194 AGALARPKVPSRNRVIGKSKKFSESVLRTQIRHMKFGAFALYKPPPAPLVAPSPG----- 248
Query: 356 LDLQSVKNGMPGVGLLARHATATKGVPATNPAPGKGTGSGLIGASGATMPTDTSKSE--- 412
+ PG GLL A AP SG +SG PT S
Sbjct: 249 ----KAEASAPGPGLLL----------AAPAAPYDARSSG---SSGCPSPTPQSSDPDDT 291
Query: 413 --KLASRAVAPPTPASKRDCVKGSATP--SGQESRTAPGEARKAATLPEMSAGEESSSSD 468
KL V+P P+ + V + P S S+ AP E AA P E + +
Sbjct: 292 PPKLLPETVSPSAPSWREPEVLDLSLPPESAATSKRAPPEVTAAAG-PAPPTAPEPAGAS 350
Query: 469 SDPDSASPPSTGQNPSVSVQTSQDWKPTRSLIEHVFVTDVTANLITVTVKE 519
S+P++ DW+P S +V VTDVT+NL+TVT+KE
Sbjct: 351 SEPEAG-----------------DWRPEMSPCSNVVVTDVTSNLLTVTIKE 384
>gi|28372505 chromobox homolog 7 [Homo sapiens]
Length = 251
Score = 102 bits (253), Expect = 1e-21
Identities = 45/76 (59%), Positives = 61/76 (80%), Gaps = 1/76 (1%)
Query: 3 ELSSVGEQVFAAECILSKRLRKGKLEYLVKWRGWSSKHNSWEPEENILDPRLLLAFQKKE 62
ELS++GEQVFA E I KR+RKGK+EYLVKW+GW K+++WEPEE+ILDPRL++A+++KE
Sbjct: 2 ELSAIGEQVFAVESIRKKRVRKGKVEYLVKWKGWPPKYSTWEPEEHILDPRLVMAYEEKE 61
Query: 63 HEKEVQN-RKRGKRPR 77
RKRG +P+
Sbjct: 62 ERDRASGYRKRGPKPK 77
Score = 38.5 bits (88), Expect = 0.015
Identities = 32/94 (34%), Positives = 38/94 (40%), Gaps = 23/94 (24%)
Query: 437 PSGQESRTAPGEARKAATLPEMSAGEESSSSDSDPDSASPPSTGQNPSVSVQTSQDWKPT 496
P + A GE AA PE A D+D PP T PS
Sbjct: 177 PPAPDVLQAAGEWEPAAQPPEEEA-------DADLAEGPPPWTPALPS------------ 217
Query: 497 RSLIEHVFVTDVTANLITVTVKESPTSVGFFNLR 530
V VTD+TAN ITVT +E+ + GFF R
Sbjct: 218 ----SEVTVTDITANSITVTFREAQAAEGFFRDR 247
>gi|188035910 heterochromatin protein 1-alpha [Homo sapiens]
Length = 191
Score = 71.6 bits (174), Expect = 2e-12
Identities = 39/107 (36%), Positives = 60/107 (56%), Gaps = 9/107 (8%)
Query: 5 SSVGEQVFAAECILSKRLRKGKLEYLVKWRGWSSKHNSWEPEENILDPRLLLAFQKK-EH 63
SS E+ + E +L +R+ KG++EYL+KW+G+S +HN+WEPE+N+ P L+ F KK +
Sbjct: 13 SSEDEEEYVVEKVLDRRVVKGQVEYLLKWKGFSEEHNTWEPEKNLDCPELISEFMKKYKK 72
Query: 64 EKEVQNRKRGKRPRGRPRKLTAMSSCSRRSKLKEPDAPSKSKSSSSS 110
KE +N K ++ RK +S D SK K S+
Sbjct: 73 MKEGENNKPREKSESNKRKSNFSNSAD--------DIKSKKKREQSN 111
>gi|188035908 heterochromatin protein 1-alpha [Homo sapiens]
Length = 191
Score = 71.6 bits (174), Expect = 2e-12
Identities = 39/107 (36%), Positives = 60/107 (56%), Gaps = 9/107 (8%)
Query: 5 SSVGEQVFAAECILSKRLRKGKLEYLVKWRGWSSKHNSWEPEENILDPRLLLAFQKK-EH 63
SS E+ + E +L +R+ KG++EYL+KW+G+S +HN+WEPE+N+ P L+ F KK +
Sbjct: 13 SSEDEEEYVVEKVLDRRVVKGQVEYLLKWKGFSEEHNTWEPEKNLDCPELISEFMKKYKK 72
Query: 64 EKEVQNRKRGKRPRGRPRKLTAMSSCSRRSKLKEPDAPSKSKSSSSS 110
KE +N K ++ RK +S D SK K S+
Sbjct: 73 MKEGENNKPREKSESNKRKSNFSNSAD--------DIKSKKKREQSN 111
>gi|6912292 heterochromatin protein 1-alpha [Homo sapiens]
Length = 191
Score = 71.6 bits (174), Expect = 2e-12
Identities = 39/107 (36%), Positives = 60/107 (56%), Gaps = 9/107 (8%)
Query: 5 SSVGEQVFAAECILSKRLRKGKLEYLVKWRGWSSKHNSWEPEENILDPRLLLAFQKK-EH 63
SS E+ + E +L +R+ KG++EYL+KW+G+S +HN+WEPE+N+ P L+ F KK +
Sbjct: 13 SSEDEEEYVVEKVLDRRVVKGQVEYLLKWKGFSEEHNTWEPEKNLDCPELISEFMKKYKK 72
Query: 64 EKEVQNRKRGKRPRGRPRKLTAMSSCSRRSKLKEPDAPSKSKSSSSS 110
KE +N K ++ RK +S D SK K S+
Sbjct: 73 MKEGENNKPREKSESNKRKSNFSNSAD--------DIKSKKKREQSN 111
>gi|5803076 heterochromatin protein 1-beta [Homo sapiens]
Length = 185
Score = 66.6 bits (161), Expect = 5e-11
Identities = 43/136 (31%), Positives = 68/136 (50%), Gaps = 12/136 (8%)
Query: 1 MEELSSVGEQVFAAECILSKRLRKGKLEYLVKWRGWSSKHNSWEPEENILDPRLLLAF-- 58
+EE+ E+ + E +L +R+ KGK+EYL+KW+G+S + N+WEPEEN+ P L+ F
Sbjct: 10 VEEVLEEEEEEYVVEKVLDRRVVKGKVEYLLKWKGFSDEDNTWEPEENLDCPDLIAEFLQ 69
Query: 59 -QKKEHE--------KEVQNRKRGKRPRGRPRKLTAMSSCSRR-SKLKEPDAPSKSKSSS 108
QK HE ++ + K +P+K S R ++ EP+ + SS
Sbjct: 70 SQKTAHETDKSEGGKRKADSDSEDKGEESKPKKKKEESEKPRGFARGLEPERIIGATDSS 129
Query: 109 SSSSSTSSSSSSDEED 124
+SDE D
Sbjct: 130 GELMFLMKWKNSDEAD 145
>gi|187960037 heterochromatin protein 1-beta [Homo sapiens]
Length = 185
Score = 66.6 bits (161), Expect = 5e-11
Identities = 43/136 (31%), Positives = 68/136 (50%), Gaps = 12/136 (8%)
Query: 1 MEELSSVGEQVFAAECILSKRLRKGKLEYLVKWRGWSSKHNSWEPEENILDPRLLLAF-- 58
+EE+ E+ + E +L +R+ KGK+EYL+KW+G+S + N+WEPEEN+ P L+ F
Sbjct: 10 VEEVLEEEEEEYVVEKVLDRRVVKGKVEYLLKWKGFSDEDNTWEPEENLDCPDLIAEFLQ 69
Query: 59 -QKKEHE--------KEVQNRKRGKRPRGRPRKLTAMSSCSRR-SKLKEPDAPSKSKSSS 108
QK HE ++ + K +P+K S R ++ EP+ + SS
Sbjct: 70 SQKTAHETDKSEGGKRKADSDSEDKGEESKPKKKKEESEKPRGFARGLEPERIIGATDSS 129
Query: 109 SSSSSTSSSSSSDEED 124
+SDE D
Sbjct: 130 GELMFLMKWKNSDEAD 145
>gi|41055989 M-phase phosphoprotein 8 [Homo sapiens]
Length = 860
Score = 64.7 bits (156), Expect = 2e-10
Identities = 58/196 (29%), Positives = 89/196 (45%), Gaps = 22/196 (11%)
Query: 8 GEQVFAAECILSKRLRKGKLEYLVKWRGWSSKHNSWEPEENILD-PRLLLAFQKKEHEKE 66
GE VF E IL + GK+ Y V+W+G++S ++WEPE ++ D +LL F+KK E +
Sbjct: 55 GEDVFEVEKILDMKTEGGKVLYKVRWKGYTSDDDTWEPEIHLEDCKEVLLEFRKKIAENK 114
Query: 67 VQN-RKRGKRPRGRPRKLTAMSSCSRRSKLKEPDAPSKSKSSSSSSSSTSSSSSSDEEDD 125
+ RK +R A S ++S+ KE +P K K +E+
Sbjct: 115 AKAVRKDIQRLSLNNDIFEANSDSDQQSETKEDTSPKKKK---------KKLRQREEKSP 165
Query: 126 SDLDAKRGPRGR---ETHPVPQKKAQILVAKPELKDPIRK-----KRGRKPLPPEQKATR 177
DL K+ G+ ++ P + + LV K I + K +KP E K T+
Sbjct: 166 DDLKKKKAKAGKLKDKSKPDLESSLESLVFDLRTKKRISEAKEELKESKKPKKDEVKETK 225
Query: 178 RPVSLAKVLKTARKDL 193
L KV K +DL
Sbjct: 226 ---ELKKVKKGEIRDL 238
>gi|15082258 chromobox homolog 3 [Homo sapiens]
Length = 183
Score = 63.2 bits (152), Expect = 6e-10
Identities = 33/94 (35%), Positives = 50/94 (53%), Gaps = 8/94 (8%)
Query: 12 FAAECILSKRLRKGKLEYLVKWRGWSSKHNSWEPEENILDPRLLLAFQKKEHEKEVQNRK 71
F E +L +R+ GK+EY +KW+G++ N+WEPEEN+ P L+ AF + ++K
Sbjct: 30 FVVEKVLDRRVVNGKVEYFLKWKGFTDADNTWEPEENLDCPELIEAF--------LNSQK 81
Query: 72 RGKRPRGRPRKLTAMSSCSRRSKLKEPDAPSKSK 105
GK G RK + S K+ DA K +
Sbjct: 82 AGKEKDGTKRKSLSDSESDDSKSKKKRDAADKPR 115
>gi|20544151 chromobox homolog 3 [Homo sapiens]
Length = 183
Score = 63.2 bits (152), Expect = 6e-10
Identities = 33/94 (35%), Positives = 50/94 (53%), Gaps = 8/94 (8%)
Query: 12 FAAECILSKRLRKGKLEYLVKWRGWSSKHNSWEPEENILDPRLLLAFQKKEHEKEVQNRK 71
F E +L +R+ GK+EY +KW+G++ N+WEPEEN+ P L+ AF + ++K
Sbjct: 30 FVVEKVLDRRVVNGKVEYFLKWKGFTDADNTWEPEENLDCPELIEAF--------LNSQK 81
Query: 72 RGKRPRGRPRKLTAMSSCSRRSKLKEPDAPSKSK 105
GK G RK + S K+ DA K +
Sbjct: 82 AGKEKDGTKRKSLSDSESDDSKSKKKRDAADKPR 115
>gi|92859678 small nuclear RNA activating complex, polypeptide 4,
190kDa [Homo sapiens]
Length = 1469
Score = 60.5 bits (145), Expect = 4e-09
Identities = 106/428 (24%), Positives = 156/428 (36%), Gaps = 77/428 (17%)
Query: 83 LTAMSSCSRRSKLKEPDAPSKSKSSSSSSSSTSSSSSSDEE---DDSDLDAKRGPRGRET 139
L A SS P+ P++ S S+S + +SS E + L A GPR
Sbjct: 832 LQASSSAQSTPGHLFPNVPAQEASKSASHKGSRRLASSRVERTLPQASLLASTGPR---- 887
Query: 140 HPVPQKKAQILVAKPELKDPIRKKRGRKPLPPEQKATRRPVSLAKVLKTARKDLGAPASK 199
P P+ +++L K +++ R R+ ATR PV L L + +
Sbjct: 888 -PKPKTVSELLQEKR-----LQEARARE-------ATRGPVVLPSQLLVSSSVI------ 928
Query: 200 LPPPLSAPVAGLAALKAHAKEACGGPSAMATPENLASLMKGMASSPGRGGISWQSSIVHY 259
L PPL G A GP+ + P L+ A+ PG G SWQ +
Sbjct: 929 LQPPLPHTPHGRPA---------PGPTVLNVP--LSGPGAPAAAKPGTSG-SWQEAGTSA 976
Query: 260 MN-RMTQSQAQAASRLALKAQATNKCGLGLDLKVRTQKGELGMSPPGSKIPKAPSGGAVE 318
+ R++ QA + + +A+ T G++ +S P S + ++ + A
Sbjct: 977 KDKRLSTMQALPLAPVFSEAEGTAPAA---SQAPALGPGQISVSCPESGLGQSQAPAA-S 1032
Query: 319 QKVGNTGGPPHTHGASRVPAGCPGPQPAPTQELSLQVLDLQSVKNG--MPGVGLLARHAT 376
+K G PP A P P P P Q LSL + V +P +L
Sbjct: 1033 RKQGLPEAPPFLPAA-------PSPTPLPVQPLSLTHIGGPHVATSVPLPVTWVLTAQGL 1085
Query: 377 ATKGVPATNPAPGKGTGSGLIGASGATMPTDTSKSEKLASRAVA------PP-------- 422
VPA P G G +P T RA A PP
Sbjct: 1086 LPVPVPAVVSLPRPAGTPGPAGLLATLLPPLTETRAAQGPRAPALSSSWQPPANMNREPE 1145
Query: 423 ------TPASKRDCVKGSATPSGQESRTAPGEARKAATLPEMSAGEESSSSDSDPDSASP 476
TPA + S + PGEA+ A +PE +SS +DP A P
Sbjct: 1146 PSCRTDTPAPPTHALSQSPAEADGSVAFVPGEAQVAREIPE-----PRTSSHADPPEAEP 1200
Query: 477 PSTGQNPS 484
P +G+ P+
Sbjct: 1201 PWSGRLPA 1208
Score = 35.0 bits (79), Expect = 0.17
Identities = 47/158 (29%), Positives = 64/158 (40%), Gaps = 40/158 (25%)
Query: 65 KEVQNRKRG-KRPRGRPRKLTAMSSCSRRSKLKEPDAPSKSKSSSSSSSSTSSSSSSDEE 123
K + +K+G +R R R R SS S S S S SS SS+SSSSSS+E+
Sbjct: 496 KIMMGKKQGLRRRRRRARHSVRWSSTSS----------SGSSSGSSGGSSSSSSSSSEED 545
Query: 124 DDSDLDAKRGPRGRETHPVPQKKAQILVAKPELKDPIRKKRGRKPLPPEQKATRRPVSLA 183
+ A G R Q +V +L P R ++T +P
Sbjct: 546 EPEQAQAGEGDRA-------LLSPQYMVPDMDLWVPAR------------QSTSQPWR-- 584
Query: 184 KVLKTARKDLGAPASKLPPPLSAPVAGLAALKAHAKEA 221
A LG PA+ L PP G +A + +KEA
Sbjct: 585 ---GGAGAWLGGPAASLSPP-----KGSSASQGGSKEA 614
>gi|27734775 hypothetical protein LOC286499 [Homo sapiens]
Length = 248
Score = 56.2 bits (134), Expect = 7e-08
Identities = 41/151 (27%), Positives = 75/151 (49%), Gaps = 4/151 (2%)
Query: 42 SWEPEENILDPRLLLAFQKKEHEKEVQNRKRGKRPRGRPRKLTAMSSCSRRSKLKEPDAP 101
+WE + L+ + + E E+++ + + + R + L+ S S++ + K+
Sbjct: 40 TWEEVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKK 99
Query: 102 SKSKSSSSSSSSTSSSSSSDEEDDSDLDAKRGPRGRETHPVPQKKAQILVAKPELKDPIR 161
+SSSSSSSS SSSSSSD ED+ KR + ++ ++ ++ E K+ ++
Sbjct: 100 KSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKK-KKNRSYKSSQSSTHESESESKESVK 158
Query: 162 KKRGRKPLPPEQKATRRPVSLAKVLKTARKD 192
KK+ K ++K R SL+K K + D
Sbjct: 159 KKKKSKDETEKEKDVR---SLSKKRKKSYPD 186
Score = 32.0 bits (71), Expect = 1.4
Identities = 27/125 (21%), Positives = 52/125 (41%), Gaps = 4/125 (3%)
Query: 64 EKEVQNRKRGKRPRGRPRKLTAMSSCSRRSKLKEP-DAPSKSKSSSSSSSSTSSSSSSDE 122
++E + KR K+ + R K + S+ S+ KE KSK + S S +
Sbjct: 122 DEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDVRSLSKKRK 181
Query: 123 E---DDSDLDAKRGPRGRETHPVPQKKAQILVAKPELKDPIRKKRGRKPLPPEQKATRRP 179
+ DD L ++ V KK + + + K+ ++KK+ ++ +K ++
Sbjct: 182 KSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQHKKHSKKKKKKS 241
Query: 180 VSLAK 184
S K
Sbjct: 242 GSSHK 246
Score = 30.0 bits (66), Expect = 5.5
Identities = 31/113 (27%), Positives = 47/113 (41%), Gaps = 19/113 (16%)
Query: 59 QKKEHEKEVQNR---KRGKRPRGRPRKLTAMSSCSRRSKLKEPD-APSKSKSSSSSSSST 114
Q HE E +++ K+ K+ + K + S S++ K PD P S+
Sbjct: 143 QSSTHESESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSE--------- 193
Query: 115 SSSSSSDEEDDSDLDAKRGPRGRETHPVPQKKAQILVAKPELKDPIRKKRGRK 167
SSS SD E+D KR RE Q K ++ K + KK+ +K
Sbjct: 194 -SSSESDYEEDVQAKKKRRCEERE-----QAKEKVKKKKKKQHKKHSKKKKKK 240
>gi|221307494 chromodomain protein, Y chromosome-like isoform a
[Homo sapiens]
Length = 544
Score = 55.1 bits (131), Expect = 2e-07
Identities = 56/226 (24%), Positives = 108/226 (47%), Gaps = 25/226 (11%)
Query: 9 EQVFAAECILSKRL-RKGKLEYLVKWRGWSSKHNSWEPEENILD-PRLLLAFQKKEHEKE 66
E+++ E I+ KR +KGK EYLV+W+G+ S+ ++WEPE+++++ + F ++ EK+
Sbjct: 4 EELYEVERIVDKRKNKKGKTEYLVRWKGYDSEDDTWEPEQHLVNCEEYIHDFNRRHTEKQ 63
Query: 67 VQN--RKRGKRPRGRPRKLTAMSSCSRRSKL--------KEPDAPSKSKSSSSSSSSTSS 116
++ + + RK + S+ S SK K+ ++ + ++S ++
Sbjct: 64 KESTLTRTNRTSPNNARKQISRSTNSNFSKTSPKALVIGKDHESKNSQLFAASQKFRKNT 123
Query: 117 SSSSDEEDDSDLDAKRGPRGR-ETHPVPQKKA--QILVAKPELKDPIRKKRGRKPLPPEQ 173
+ S + DL AK G + PV + A PE DP+ ++G++ +
Sbjct: 124 APSLSSRKNMDL-AKSGIKILVPKSPVKSRTAVDGFQSESPEKLDPV--EQGQEDTVAPE 180
Query: 174 KATRRPVSLAKVLKTARKDLGAP------ASKLPPPLSAPVA-GLA 212
A +PV R +G+ ++P P++A +A GLA
Sbjct: 181 VAAEKPVGALLGPGAERARMGSRPRIHPLVPQVPGPVTAAMATGLA 226
>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
Length = 2968
Score = 53.1 bits (126), Expect = 6e-07
Identities = 83/403 (20%), Positives = 148/403 (36%), Gaps = 37/403 (9%)
Query: 96 KEPDAPSKSKSSSSSSSSTSSSSSSDEEDDSDLDAKRGPRGRETHPVPQKKAQILVAKPE 155
+EP A ++ + S+ + +++ EE + + P E P K + PE
Sbjct: 2323 EEPGAKARGRGRKPSAKAKGDRAATLEEGNPTDEVPSTPLALEPSSTPGSKK----SPPE 2378
Query: 156 LKDPIRKKRGRKPLPPEQKATRRPVSLAKVLKTARKDLGAPASKLPPPLSAPVAGLAALK 215
D K +P PP Q + P + +L APA+ L P AP+ +
Sbjct: 2379 PVDKRAKAPKARPAPP-QPSPAPPAFTSCPAPEPFAELPAPATSLAP---APLITM---- 2430
Query: 216 AHAKEACGGPSAMATPENLASLMKGMASSPGRGGISWQSSIVHYMNRMTQSQAQAASRLA 275
P+ P+ + + A P R G + + +T +++ A
Sbjct: 2431 ---------PATRPKPKKARAAEESGAKGPRRPGEEAELLVKLDHEGVTSPKSKKAKEAL 2481
Query: 276 LKAQATNKCGLGLDLKVRTQKGELGMSPP--GSKIPKAPSGGAVEQKVGNTGGPPHTHGA 333
L + G + + LG PP GS PKAP A + + GP T
Sbjct: 2482 LLREDPGAGGWQEPKSLLS----LGSYPPAAGSSEPKAPWPKATDGDLAQEPGPGLTFED 2537
Query: 334 SRVPAGCPGPQPAPTQELSLQVLDLQSVKNGMPGVGLLARHATATKGVPATNPAPGKGTG 393
S P P A ++ + + +S + G + ++++ G G G
Sbjct: 2538 SGNPKS---PDKAQAEQDGAE--ESESSSSSSSGSSS-SSSSSSSSGSETEGEEEGDKNG 2591
Query: 394 SGLIGASGATMPTDTSKSEKLASRAVAPPTPASKRDCVKGSATPSGQESRTAPGEARKAA 453
G G G +S++ AS + + + +S S++ S S ++ + ++
Sbjct: 2592 DGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2651
Query: 454 TLPEMSAGEESSSSDSDPDSASPPSTGQNPSVSVQTSQDWKPT 496
+ S+ SSSS S S+S +T ++ S S PT
Sbjct: 2652 S----SSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPT 2690
Score = 44.3 bits (103), Expect = 3e-04
Identities = 33/100 (33%), Positives = 47/100 (47%), Gaps = 7/100 (7%)
Query: 84 TAMSSCSRRSKLKEPDAPSKSKSSSSSSSSTSSSSSSDEEDDSDLDAK------RGPRGR 137
++ SS S S + S S SSSSSSSS+SSSS++DE+ D + GP +
Sbjct: 2637 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQ 2696
Query: 138 ETHPVPQKKAQILVAKPELKDPIRKKRGRKPLPPEQKATR 177
P K Q A+P P +K +P P + T+
Sbjct: 2697 AALPTKATK-QAGKARPSAHSPGKKTPAPQPQAPPPQPTQ 2735
Score = 37.4 bits (85), Expect = 0.034
Identities = 28/65 (43%), Positives = 31/65 (47%), Gaps = 5/65 (7%)
Query: 62 EHEKEVQNRKRGKRPRGRPRKLTAMSSCSRRSKLKEPDAPSKSKSSSSSSSSTSSSSSSD 121
E E E + K G G T +CS S A S S SSSSSSSS+SSSSSS
Sbjct: 2580 ETEGEEEGDKNGDGGCG-----TGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSS 2634
Query: 122 EEDDS 126
S
Sbjct: 2635 SSSSS 2639
Score = 36.6 bits (83), Expect = 0.059
Identities = 33/140 (23%), Positives = 45/140 (32%)
Query: 64 EKEVQNRKRGKRPRGRPRKLTAMSSCSRRSKLKEPDAPSKSKSSSSSSSSTSSSSSSDEE 123
E+ +N G GR + + S S + S S SSSSSSSS+SSSSSS
Sbjct: 2585 EEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2644
Query: 124 DDSDLDAKRGPRGRETHPVPQKKAQILVAKPELKDPIRKKRGRKPLPPEQKATRRPVSLA 183
S + + + + + P P
Sbjct: 2645 SSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKAT 2704
Query: 184 KVLKTARKDLGAPASKLPPP 203
K AR +P K P P
Sbjct: 2705 KQAGKARPSAHSPGKKTPAP 2724
Score = 36.2 bits (82), Expect = 0.077
Identities = 60/229 (26%), Positives = 78/229 (34%), Gaps = 50/229 (21%)
Query: 45 PEENILDPRLLLAFQKKEHEKEVQNRKRGKRPRGRPRKLTAMSSCSRRSK--LKEPDAPS 102
P + L P LL + K + K K KR PR L + SR+ L +A +
Sbjct: 1751 PSSSKLTPSLLCSMVAK-NSKAAGGPKLTKRGLAAPRTLKPKPATSRKQPFCLLLREAEA 1809
Query: 103 KSKSSSSSSSSTSSSSSSDEEDD----------SDLDAKRGPRGR--------------- 137
+S S SS S SS+EED+ S + G R R
Sbjct: 1810 RSSFSDSSEESFDQDESSEEEDEEEELEEEDEASGGGYRLGARERALSPGLEESGLGLLA 1869
Query: 138 ----ETHPVPQKKAQILVAKPELKDPIRKKRGRKPL--------PPEQKATRRPVSLAKV 185
P P + V + E K RKK R+ L E + R S A +
Sbjct: 1870 RFAASALPSPTVGPSLSVVQLEAKQKARKKEERQSLLGTEFEYTDSESEVKVRKRSPAGL 1929
Query: 186 LKTARKDLGAPASKL---------PPPLSAPVAGLAALKAHAKEACGGP 225
L+ +K LG P L P P S A LA K GP
Sbjct: 1930 LR-PKKGLGEPGPSLAAPTPGARGPDPSSPDKAKLAVEKGRKARKLRGP 1977
Score = 33.1 bits (74), Expect = 0.65
Identities = 19/56 (33%), Positives = 30/56 (53%)
Query: 78 GRPRKLTAMSSCSRRSKLKEPDAPSKSKSSSSSSSSTSSSSSSDEEDDSDLDAKRG 133
G P+ + ++ E + S S SSSSSSSS+SS S ++ E++ D + G
Sbjct: 2539 GNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGG 2594
Score = 32.7 bits (73), Expect = 0.85
Identities = 24/65 (36%), Positives = 29/65 (44%)
Query: 62 EHEKEVQNRKRGKRPRGRPRKLTAMSSCSRRSKLKEPDAPSKSKSSSSSSSSTSSSSSSD 121
E E+E G G A S + + + S S SSSSSSSS+SSSSSS
Sbjct: 2582 EGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSS 2641
Query: 122 EEDDS 126
S
Sbjct: 2642 SSSSS 2646
Score = 30.8 bits (68), Expect = 3.2
Identities = 49/183 (26%), Positives = 67/183 (36%), Gaps = 25/183 (13%)
Query: 58 FQKKEHEKEVQNRKRGKRPRGRPRKLTAMSSCSRRSKLKEPDAPSKSKSSSSSSSSTSSS 117
F+ + E EV+ RKR RP+K L EP PS + + + SS
Sbjct: 1910 FEYTDSESEVKVRKRSPAGLLRPKK-----------GLGEP-GPSLAAPTPGARGPDPSS 1957
Query: 118 SSSDEEDDSDLDAKRGPRGRETHPVPQKKAQILVAKPELKDP---IRKKRGRKPLPPEQK 174
D + L ++G + R+ + + A PE D R++ R L
Sbjct: 1958 P-----DKAKLAVEKGRKARKLRGPKEPGFE---AGPEASDDDLWTRRRSERIFLHDASA 2009
Query: 175 ATRRPVSLAKVLKTARKDLGAPASKLPPPLSAPVAGLAALKAHAKEACGGPSAMATPENL 234
A PVS A KT+R G P S A K KEA GP A P
Sbjct: 2010 AAPAPVSTAPATKTSRCAKGGPLSPRKDAGRAKDRKDPRKKKKGKEA--GPGAGLPPPRA 2067
Query: 235 ASL 237
+L
Sbjct: 2068 PAL 2070
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 52.0 bits (123), Expect = 1e-06
Identities = 92/434 (21%), Positives = 148/434 (34%), Gaps = 58/434 (13%)
Query: 97 EPDAPSKSKSSSSSSSSTSSSSSSDEEDDSDLDAKRG---------PRGRETHPVPQKKA 147
+ + P K+ +SSS S SS +EE+ AK+ P G+ + +
Sbjct: 69 QANGPVAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASESSS 128
Query: 148 QILVAKPELKDPIRKKRGRKPLPPEQKATRRPVSLAKVLKTARKDLGAPASKLPP----P 203
+ + ++ +K+ +K + P+ KA + P K K++ D + + PP P
Sbjct: 129 SEESSDDDDEEDQKKQPVQKGVKPQAKAAKAP---PKKAKSSDSDSDSSSEDEPPKNQKP 185
Query: 204 LSAPVAGLAALKAHAKEACGGPSAMATPENLASLMKGMASSPGRGGISWQSSIVHYMNRM 263
PV A KA K A P + G A+S S SS +
Sbjct: 186 KITPVTVKAQTKAPPKPARAAP----------KIANGKAASSSSSSSSSSSSDDSEEEKA 235
Query: 264 TQSQAQAASRLALKAQATNKCGLGLDLKVRTQKGELGMSPPGSKIPKAPSGGAVEQKVGN 323
+ + + + A+A K K + + K P G
Sbjct: 236 AATPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPP 295
Query: 324 TGGPPHTHGASRVP-AGCPGPQPAPTQELSLQVLDLQSVKNGMPGVGLLARHATATKGVP 382
+ PP ++ P QP + E S D S + P + AT TK P
Sbjct: 296 SAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKAT-TKPPP 354
Query: 383 ATNPAPGKGTGSGLIGASGATMPTDTSKSEKLASR--AVAPPTPASKRDCV--------- 431
A A S + P+ + + K +S AV +PA K
Sbjct: 355 AKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQ 414
Query: 432 -----KGSATPSGQESRTAPGE--------------ARKAATLPEMSAGEESSSSDSDPD 472
K ++ S +ES ++ E A+ A +LP A + S S SD D
Sbjct: 415 KLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSD 474
Query: 473 SASPPSTGQNPSVS 486
S+S + S S
Sbjct: 475 SSSSEEEEEKTSKS 488
Score = 43.9 bits (102), Expect = 4e-04
Identities = 91/451 (20%), Positives = 157/451 (34%), Gaps = 66/451 (14%)
Query: 61 KEHEKEVQNRKRGKRPRGRPRKLTAMSSCSRRSKLKEPDAPS---------KSKSSSSSS 111
K + + + + P+ + K+T ++ +++ K P P+ K+ SSSSSS
Sbjct: 165 KSSDSDSDSSSEDEPPKNQKPKITPVTV---KAQTKAPPKPARAAPKIANGKAASSSSSS 221
Query: 112 SSTSSSSSSDEEDDSDLDAKRGPRGRETHPVPQKKAQILVAKPELKDPIRKKRGRKPLPP 171
SS+SSS S+EE + K P+ + P K A P RK +
Sbjct: 222 SSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAA---------TTPTRKSSSSEDSSS 272
Query: 172 EQKATRRPVSLAKVLKTARKDLGAPASKLPPPLSAPVAGLAALKAHAKEACGGPSAMATP 231
+++ + K K+ P S +PPP + P K++ G P
Sbjct: 273 DEEEEQ---------KKPMKNKPGPYSSVPPPSAPP----------PKKSLG----TQPP 309
Query: 232 ENLASLMKGMASSPGRGGISWQSSIVHYMNRMTQSQAQAASRLALKAQATNKCGLGLDLK 291
+ + + SS S SS + + A+ ++AT K K
Sbjct: 310 KKAVEKQQPVESSEDSSDESDSSS----------EEEKKPPTKAVVSKATTK---PPPAK 356
Query: 292 VRTQKGELGMSPPGSKIPKAPSGGAVEQKVGNTGGPPHTHGASRVPAGCPGPQPAPTQEL 351
+ S+ +APS A K + T + PA P Q+L
Sbjct: 357 KAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKL 416
Query: 352 SLQVLDLQSVKNGMPGVGLLARHATATKGVPATNPAPGKGTGSGLIGASGATMPTDTSKS 411
+ D S + + TK + AT + + A A + S S
Sbjct: 417 LTRKADSSSSEEESS-----SSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSS 471
Query: 412 EKLASRAVAPPTPASKRDCVKGSATPSGQESRTAPGEARKAATLPEMSAGEESSSSDSD- 470
+ +S + SK K +G + + P A+K S+ + SS + +
Sbjct: 472 DSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEE 531
Query: 471 --PDSASP-PSTGQNPSVSVQTSQDWKPTRS 498
SP P + S T+Q+ K ++
Sbjct: 532 KLKGKGSPRPQAPKANGTSALTAQNGKAAKN 562
Score = 32.7 bits (73), Expect = 0.85
Identities = 24/100 (24%), Positives = 37/100 (37%)
Query: 56 LAFQKKEHEKEVQNRKRGKRPRGRPRKLTAMSSCSRRSKLKEPDAPSKSKSSSSSSSSTS 115
L +K + + + + + T + ++ L P + S SSS S S
Sbjct: 416 LLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDS 475
Query: 116 SSSSSDEEDDSDLDAKRGPRGRETHPVPQKKAQILVAKPE 155
SSS +EE S K+ P+ P K A K E
Sbjct: 476 SSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAE 515
Score = 30.0 bits (66), Expect = 5.5
Identities = 32/103 (31%), Positives = 38/103 (36%), Gaps = 25/103 (24%)
Query: 415 ASRAVAPPTPASKRDCVKGSATPSGQESRTAPGEA--------------RKAATLPEMSA 460
A R PP A+ K S + S +ES E KAA P A
Sbjct: 109 AKRVGLPPGKAA----AKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKA 164
Query: 461 GEESSSSDSDPDSASPPSTGQNP-----SVSVQTSQDWKPTRS 498
+SS SDSD S P Q P +V QT KP R+
Sbjct: 165 --KSSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARA 205
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 51.6 bits (122), Expect = 2e-06
Identities = 40/115 (34%), Positives = 47/115 (40%)
Query: 65 KEVQNRKRGKRPRGRPRKLTAMSSCSRRSKLKEPDAPSKSKSSSSSSSSTSSSSSSDEED 124
KE R P RK + SS S S + S S SSSSSSSS+SSSSSS
Sbjct: 2587 KEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2646
Query: 125 DSDLDAKRGPRGRETHPVPQKKAQILVAKPELKDPIRKKRGRKPLPPEQKATRRP 179
S AK GP+ P+K + PI R + L RRP
Sbjct: 2647 SSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRP 2701
Score = 43.5 bits (101), Expect = 5e-04
Identities = 42/157 (26%), Positives = 62/157 (39%), Gaps = 4/157 (2%)
Query: 78 GRPRKLTAMSSCSRRSKLKEPDAPSKSKSSSSSSSSTSSSSSSDEEDDSDLDAKRGPRGR 137
G P T S + L +P +S SSSSSSSS+SSSSSS S +
Sbjct: 2507 GEPPASTGAQQPSALAAL-QPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEG 2565
Query: 138 ETHPVPQKKAQILVAKPELKDPIRKKRGRKPLPPEQKATRRPVSLAKVLKTARKDLGAPA 197
+ PV + A V P + GR P P K RR S + ++ + +
Sbjct: 2566 SSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSS 2625
Query: 198 SKLPPPLSAPVAGLAALKAHAKE---ACGGPSAMATP 231
S S+ + ++ + + A GP A+ P
Sbjct: 2626 SSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKP 2662
Score = 42.4 bits (98), Expect = 0.001
Identities = 83/412 (20%), Positives = 144/412 (34%), Gaps = 39/412 (9%)
Query: 91 RRSKLKEPDAPSKSKSSSSSSSSTSSSSSSDEEDDSDLDAKRGPRGRETHPVPQKKAQIL 150
RR++ + AP K S S+SS S + ++ RG R + P ++K
Sbjct: 155 RRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSK 214
Query: 151 VAKPELKDPIRKKRGRKPLPPEQKATRRPVSLAKVLKTARKDLGAPASKLPPPLSAPVAG 210
K + +K++ R P P ++ ++ K K +R AP S+
Sbjct: 215 KKKHRSESESKKRKHRSPTPKSKRKSK-----DKKRKRSRSTTPAPKSR------RAHRS 263
Query: 211 LAALKAHAKEACGGPSAMATPENLASLMKGMASSPGRGGISWQSSIVHYMNRMTQSQAQA 270
+A A + + S A + + + G + SP G + T +Q +
Sbjct: 264 TSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPA-SGRRGEGDAPFSEPGTTSTQRPS 322
Query: 271 ASRLALKAQATNKCGLGLDLKVRTQKGELGMSPPGSKIPKAPSGGA----VEQKVGNTGG 326
+ A K ++ D K +K SP + P A + ++ G +
Sbjct: 323 SPETATKQPSSPYEDKDKDKK---EKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQ 379
Query: 327 PPHTHGASRVPAGCPGPQPAPTQELS-------LQVLDLQSVKNGMPGVGLLARHATATK 379
P T S+ P P + +PT++ S L P ++RHA+++
Sbjct: 380 PLATTPLSQEPVN-PPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSP 438
Query: 380 GVPATNPAPGKGTGSGLIGASGATMPTDTSKSEKLASRAVA-PPTPASKRDCVKGSATPS 438
P PAPG ++ PT ++S A R + TP+ + + AT
Sbjct: 439 ESPKPAPAPGS-------HREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAK 491
Query: 439 GQESR----TAPGEARKAATLPEMSAGEESSSSDSDPDSASPPSTGQNPSVS 486
SR T G +R + S + P + Q P S
Sbjct: 492 RGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWS 543
Score = 41.6 bits (96), Expect = 0.002
Identities = 34/129 (26%), Positives = 52/129 (40%), Gaps = 2/129 (1%)
Query: 80 PRKLTAMSSCSRRSKLKEPDAPSKSKSSSSSSSSTSSSSSSDEEDDSDLDAKRGPRGRET 139
P A R + EP + + SSSSSSS+SSSSSS S + +
Sbjct: 2580 PSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2639
Query: 140 HPVPQKKAQILVAKPELKDPIRKKRGRKPLPPEQKATRRPVSLAKVLKTARKDLGAPAS- 198
+ AKP + + +KP PP ++ +R P L+ +R +P
Sbjct: 2640 SSSSSSSSSPSPAKPGPQALPKPASPKKP-PPGERRSRSPRKPIDSLRDSRSLSYSPVER 2698
Query: 199 KLPPPLSAP 207
+ P P +P
Sbjct: 2699 RRPSPQPSP 2707
Score = 40.4 bits (93), Expect = 0.004
Identities = 103/498 (20%), Positives = 171/498 (34%), Gaps = 82/498 (16%)
Query: 68 QNRKRGKRP---RGRPRKLTAMSSCSRRSKLKEPDAPSKSKSSSSSSSSTSSSSSSDEED 124
+ R R + P R R R T ++ +RS + P A + +S SSS + S++
Sbjct: 2039 RKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATP----- 2093
Query: 125 DSDLDAKRGPRGRETHPVPQKKAQI--------------LVAKPELKDPIRKKR------ 164
A R G T PV +++ P + +P+ R
Sbjct: 2094 ----PATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVL 2149
Query: 165 ---------GRKPLPPEQKATRRPVSLAKV-LKTARKDLGAPASKLPPPLSAPVAGLAAL 214
G P P+ + T P + A+ + A + ++ PP +SA AGLAA
Sbjct: 2150 QQAGGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARPPPSMSA--AGLAAR 2207
Query: 215 KAHAKEACGGPSAMATP-ENLASLMKGMASSPGRGGISWQSSIVHYMNRMTQSQAQAASR 273
+ S P NLAS + +++ + +I +N AA+
Sbjct: 2208 MSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAA 2267
Query: 274 LALKAQATNKCGLGLDLKVRTQKGELGMSPPGSKIPKAPSGGAVEQKVGNTGGPPHTHGA 333
+ L + T ++L ++ G++ P A + +G PP A
Sbjct: 2268 MNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAA----LAALSLTGSGTPP---TA 2320
Query: 334 SRVPAGCPGPQPAPTQELSLQVLDLQSVKNGMPGVGLLARHATATKGVPATNPAPGKGTG 393
+ P+ PQ + L VG + HATA + G T
Sbjct: 2321 ANYPSSSRTPQAPASANL----------------VGPRSAHATAPVNI------AGSRTA 2358
Query: 394 SGLIGASGATMPTDTSKSEKLASRAVAPPTPASKRDCVKGSATP---SGQESRTAPGEAR 450
+ L AS + + S + +P P S + V G +P SRT P
Sbjct: 2359 AALAPASLTSARMAPALS---GANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPS 2415
Query: 451 KAATLPEMSAGEESSSSDSDPDSASPPSTGQNPSVSVQTSQDWKPTRSLIEHVFVTDVTA 510
++ E + S + S PP+ Q S D +R LI +
Sbjct: 2416 QSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSD--QSRCLIAQTTPVAGSQ 2473
Query: 511 NLITVTVKESPTSVGFFN 528
+L + V + +S G N
Sbjct: 2474 SLSSGAVATTTSSAGDHN 2491
Score = 40.4 bits (93), Expect = 0.004
Identities = 33/105 (31%), Positives = 42/105 (40%), Gaps = 4/105 (3%)
Query: 71 KRGKRPRGRPRKLTAMSSCSRRSKLKEPDAPSKSKSSSSSS--SSTSSSSSSDEEDDSDL 128
KR P P++ + K S S SSSSSS SS+SSSSSS S
Sbjct: 2577 KRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2636
Query: 129 DAKRGPRGRETHPVPQKKAQILVAKP--ELKDPIRKKRGRKPLPP 171
+ + P P K + KP K P ++R R P P
Sbjct: 2637 SSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKP 2681
Score = 39.7 bits (91), Expect = 0.007
Identities = 95/472 (20%), Positives = 167/472 (35%), Gaps = 42/472 (8%)
Query: 35 GWSSKHNSWEPEENILDPRLLLAFQKKEHEKE--VQNRKRGKRP--RGRPRKLT------ 84
GWS N+ R A + + H + + R R + P RGR R T
Sbjct: 541 GWSRSRNTQRRG------RSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRS 594
Query: 85 -AMSSCSRRSKLKEPDAPSKSKSSSSSSSSTSSSSSSDEEDDSDLDAKRGPRGRETHPVP 143
+ + RRS+ + P +S+S + + + + S S A+R R R P
Sbjct: 595 RSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPAR 654
Query: 144 QKKAQILVAKPELKDPIRKKRGRKPLPPEQKATRRPVSLAKVLKTARKDLGAPASKLPPP 203
+ +++ + P R+ R R P + R + A + R P
Sbjct: 655 RGRSR-------SRTPARRGRSRSRTPARRSGRSRSRTPA---RRGRSRSRTPRRGRSRS 704
Query: 204 LSAPVAGLAALKAHAKEACGGPSAMATPENLASLMKGMASSPGRGGISWQSSIVHYMNRM 263
S G + + + G S+ ++ S + ++S S SS +
Sbjct: 705 RSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISS--RRSRSL 762
Query: 264 TQSQAQAASRLALKAQATNKCGLGLDLKVRTQKGELGMSPPGSKIPKAPSGGAVEQKVGN 323
+ +++A SRL+L+ + G K ++Q S GS PKA S + +
Sbjct: 763 SSPRSKAKSRLSLRRSLS---GSSPCPKQKSQTPP-RRSRSGSSQPKAKSRTPPRRSRSS 818
Query: 324 TGGPP--HTHGASRVPAGCPGPQP---APTQELSLQVLDLQSVKNGMPGVGLLARHATAT 378
+ PP + SR P P + T + Q+ + + ++
Sbjct: 819 SSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPD 878
Query: 379 KGVPATNPAPGKGTGSGLIGASGATMPTDT-SKSEKLASRAVAPPTPASKRDCVKGSATP 437
+ + P+ +GS +T P + S+S + A +P + S +P
Sbjct: 879 PELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSP 938
Query: 438 SGQESRTAPGEARKAATLPEMSA---GEESSSSDSDPDSASPPSTGQNPSVS 486
S SRT P +R + + + S S S PD+ P T S S
Sbjct: 939 SRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHS 990
Score = 39.7 bits (91), Expect = 0.007
Identities = 96/451 (21%), Positives = 158/451 (35%), Gaps = 51/451 (11%)
Query: 68 QNRKRGKRPRGRPRKLTAMSSCSRRSKLKEPDAPSKSKSSSSSSSSTSSSSSSDEEDDSD 127
++R R RGR R T RR + + + +S S + S SS E +
Sbjct: 680 RSRSRTPARRGRSRSRTP-----RRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKS 734
Query: 128 LDAKRGPRGRETHPVPQKKAQILVAKPELKDPIRKKRGRKPLPPEQKATRRPVSLAKVLK 187
++R R + P+ K K I +R R P KA R +SL + L
Sbjct: 735 RTSQRRSRSNSS---PEMK----------KSRISSRRSRSLSSPRSKAKSR-LSLRRSL- 779
Query: 188 TARKDLGAPASKLPPPLSAPVAGLAALKAHAKEACGGPSAMATPENLASLMKGMASSPGR 247
+ S+ PP S + K+ S+ P+ + + S
Sbjct: 780 SGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSS 839
Query: 248 GGISWQSSIVHYMNRMTQSQAQAASRLALKAQATNKCGLGLDLKVRTQKGELGMSPPGSK 307
+S +T QA S + + ++ + +LK RT S GS
Sbjct: 840 PHPKVKSGTPPRQGSITSPQANEQS-VTPQRRSCFESSPDPELKSRTPSRH---SCSGSS 895
Query: 308 IPKAPSGGAVEQKVGNTGGPPHTHGA-----SRVPAGCPGPQPA-----PTQELSLQVLD 357
P+ S Q + P A R +G P P+ T S V
Sbjct: 896 PPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSP 955
Query: 358 LQSVKNGMPGVGLLARHATATKGVPATN---PAPGKGTGSGLIGASGATMPTDTSKSEKL 414
+V++ LL R++ + P T P + + SG I + T L
Sbjct: 956 CSNVESR-----LLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPY-PKVKAQTPPGPSL 1009
Query: 415 ASRAVAPPTPASK----RDCVKGSATPSGQESRTAPGEARKAATLPEMSAGEESSSSDSD 470
+ P SK + C + +G +S T PGE+ + ++ G+ +S D
Sbjct: 1010 SGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLK-GQSQTSPDHR 1068
Query: 471 PDSASP---PSTGQNPSVSVQTSQDWKPTRS 498
D++SP S ++PS+ ++ K RS
Sbjct: 1069 SDTSSPEVRQSHSESPSLQSKSQTSPKGGRS 1099
Score = 38.1 bits (87), Expect = 0.020
Identities = 30/99 (30%), Positives = 44/99 (44%), Gaps = 7/99 (7%)
Query: 73 GKRPRGRPRKLTAMSSCSRRSKLKEPDAPSKSKSSSSSSSSTSSSSSSDE-EDDSDLDAK 131
G+ P + + + + +K + + S S SSSSSSSS+SSSSSS SD +
Sbjct: 2507 GEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGS 2566
Query: 132 RGP------RGRETHPVPQKKAQILVAKPELKDPIRKKR 164
P R P P K + +P P ++KR
Sbjct: 2567 SLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKR 2605
Score = 37.4 bits (85), Expect = 0.034
Identities = 41/180 (22%), Positives = 71/180 (39%), Gaps = 20/180 (11%)
Query: 75 RPRGRPRKLTAMSSCSRRSKLKEPDA-PSKSKSSSSSSS---STSSSSSSDEEDDSDLDA 130
+PR PR + S S K P A P +S+S SSS S SSS++ + +
Sbjct: 1607 KPRAAPRAQSGSDS-SPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKS 1665
Query: 131 KRGPRGRETHPVPQKKAQILVAKPELKDPIRKKRGRKPLPPEQKATRRPVSLAKVLKTAR 190
+ RG + P P+ K++ + R R L + + +RR S + +T
Sbjct: 1666 RTARRGSRSSPEPKTKSRTPPRR-------RSSRSSPELTRKARLSRRSRSASSSPETRS 1718
Query: 191 KDLGAPASKLPPPLSAPVAGLAALKAHAKEACGGPSAMATPENLASLMKGMASSPGRGGI 250
+ P + P +S+P + + + + P T +G + SP G+
Sbjct: 1719 RT--PPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSR------RGRSPSPKPRGL 1770
Score = 37.4 bits (85), Expect = 0.034
Identities = 37/186 (19%), Positives = 72/186 (38%), Gaps = 35/186 (18%)
Query: 323 NTGGPPHTHGASRVPAGCPGPQPAPTQELSLQVLDLQSVKNGMPGVGLLARHATATKGVP 382
+ G PP + GA + P+ QPA + S + ++++
Sbjct: 2505 DVGEPPASTGAQQ-PSALAALQPAKERRSSSS-----------------SSSSSSSSSSS 2546
Query: 383 ATNPAPGKGTGSGLIGASGATMPTDTSKSEKLASRAVAPPTPASKRDCVKG--------- 433
+++ + +GS + G+++P ++A + V PTPA K +G
Sbjct: 2547 SSSSSSSSSSGSSSSDSEGSSLPVQP----EVALKRVPSPTPAPKEAVREGRPPEPTPAK 2602
Query: 434 ----SATPSGQESRTAPGEARKAATLPEMSAGEESSSSDSDPDSASPPSTGQNPSVSVQT 489
S++ S S ++ + +++ S+ SSSS S S+SP P +
Sbjct: 2603 RKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKP 2662
Query: 490 SQDWKP 495
+ KP
Sbjct: 2663 ASPKKP 2668
Score = 37.0 bits (84), Expect = 0.045
Identities = 32/114 (28%), Positives = 51/114 (44%), Gaps = 10/114 (8%)
Query: 375 ATATKGVP--ATNPAPGKGTGSGLIGASGATMPTDTSKSEKLASRAVAPPTPASKRDCVK 432
A A + +P + + + KG G G+S T++S SR + +S K
Sbjct: 1626 APAPRALPRRSRSGSSSKGRGPSPEGSSS----TESSPEHPPKSRTARRGSRSSPEPKTK 1681
Query: 433 GSATPSGQESRTAPGEARKAATLPEMSAGEESSSSDSDPDSASPPSTGQNPSVS 486
P + SR++P RKA +S S+SS + S +PP ++PSVS
Sbjct: 1682 SRTPPRRRSSRSSPELTRKA----RLSRRSRSASSSPETRSRTPPRHRRSPSVS 1731
Score = 36.2 bits (82), Expect = 0.077
Identities = 27/108 (25%), Positives = 44/108 (40%), Gaps = 12/108 (11%)
Query: 71 KRGKRPRGRPRKLTAMSSCSRRSKLKEPDAPSKSKSSSSSSSSTSSSSSSDEEDDSDLDA 130
+RG+ P +PR L S SRR K + ++ + S SS STS
Sbjct: 1758 RRGRSPSPKPRGLQRSRSRSRREKTR----TTRRRDRSGSSQSTSRRRQRSRSRSRVTRR 1813
Query: 131 KRGPRGRETHPVPQKKAQILVAKPELKDPIRKKRGRKPLPPEQKATRR 178
+RG G + ++++ + R++RGR PP + R
Sbjct: 1814 RRGGSGYHSRSPARQESS--------RTSSRRRRGRSRTPPTSRKRSR 1853
Score = 35.4 bits (80), Expect = 0.13
Identities = 85/426 (19%), Positives = 150/426 (35%), Gaps = 64/426 (15%)
Query: 101 PSKSKSSSSSSSSTSS------SSSSDEEDDSDLDAKRGPRGRETHPVPQKKAQILVAKP 154
P + +S + SS T +SS DEE ++ P G+ + + ++ +
Sbjct: 1209 PPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNF 1268
Query: 155 ELKDPIRKKRGRKPLPPEQKATRRPVSLAKVLKTARKDLGAPASKLPPPLSAPVAGLAAL 214
E P ++R L +Q ++ + +V A G S LS +
Sbjct: 1269 E-SSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSF 1327
Query: 215 KAHAKEACGGPSAMATPENLASLMKGMASSPGRGGISWQSSIVHYMNRMTQSQAQAASRL 274
+ + GP +S +K + P + S+ + T+S ++S L
Sbjct: 1328 GSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSL-DMKEQSTRSSGHSSSEL 1386
Query: 275 ALKAQATNKCGLGLDLKVRTQKGELGMSPPGSKIPKAPSGGAVEQKVGNTGGPPHTHGAS 334
+ A K G+ + + SP +P+ PS ++ + P G
Sbjct: 1387 S--PDAVEKAGMSSNQSIS--------SPVLDAVPRTPS----RERSSSASSPEMKDGLP 1432
Query: 335 RVPAGCPGPQPAPTQELSLQVLDLQSVKNGMPGVGLLARHATATKGVPATNPAPGKGTGS 394
R P+ +P S+ PG+ K +P T P +G
Sbjct: 1433 RTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGM----------KDIPRT---PSRGRSE 1479
Query: 395 GLIGASGATMPTDTSKSEKLASRAVAPP-------TPASKRDCVKGSA-------TPSGQ 440
+ P ++ + SR+ + P TP +R + S TP GQ
Sbjct: 1480 ----CDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQ 1535
Query: 441 ESRTAPGEARKAATLPEMSAGEESSSSDSDPDSASPPST--------GQNPSVSVQTSQD 492
SR+ G +++ P S +E S SDS PDS + T G +P V ++
Sbjct: 1536 RSRS--GSSQELDVKPSASP-QERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLS 1592
Query: 493 WKPTRS 498
+ +RS
Sbjct: 1593 PRRSRS 1598
Score = 34.3 bits (77), Expect = 0.29
Identities = 40/175 (22%), Positives = 66/175 (37%), Gaps = 29/175 (16%)
Query: 59 QKKEHEKEVQNRKRGKRPRGRPRKLTAMSSCSRRSKLKEPDAPSKSKSSSSSSSSTSSSS 118
+KK+H E +++KR R K + +RS+ P AP ++ S+S+ ++SSS
Sbjct: 214 KKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTP-APKSRRAHRSTSADSASSS 272
Query: 119 SSDEEDDSDLDAK--------------RGPRGRETHPV-------------PQKKAQILV 151
+ AK G RG P P+ +
Sbjct: 273 DTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPS 332
Query: 152 AKPELKDPIRK-KRGRKPLPPEQKATRRPVSLAKVLKTARKDLGAPASKLPPPLS 205
+ E KD +K K +P P ++++ P A A + G+P PLS
Sbjct: 333 SPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLS 387
Score = 32.7 bits (73), Expect = 0.85
Identities = 112/529 (21%), Positives = 176/529 (33%), Gaps = 116/529 (21%)
Query: 72 RGKRPRGRP----RKLTAMSSCSRRSKLKEPDAPSKSKSSSSS----SSSTSSSSSSDEE 123
RGKR R R+ +A S S RS+ P A S + +SS S S
Sbjct: 2063 RGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSM 2122
Query: 124 DDSDLDAKRGP-------RGRETHPVPQKKAQILVAKPELKDPIRKKRGRKPLPPEQKAT 176
+ LD R P R V Q+ ++ P + P + R +P +
Sbjct: 2123 SPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQ---RTSVPENHAQS 2179
Query: 177 RRPVSLAKV-LKTARKD-------LGAPASKLPPPL------SAPVAGLAALKAHAKEAC 222
R ++L + L TAR L A S++P P+ +AP A LA+ A A
Sbjct: 2180 RIALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAA 2239
Query: 223 GGPSAMATPE-----NLASLMKGMASSPGRGGISWQSSIVHYMNRMTQSQAQAASRLALK 277
++ TP NLA + A++ S ++++ + + A + L
Sbjct: 2240 MNLASARTPAIPTAVNLAD-SRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLA 2298
Query: 278 AQATNKCGLGLDLKVRTQKGELGMSPPGSKIPKAP-SGGAVEQKVGNTGGPPHTHGASRV 336
T L L P S+ P+AP S V + + P + G+
Sbjct: 2299 GARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTA 2358
Query: 337 PAGCPGPQPAPTQELSLQVLDLQSVK---------NGMPGVGLLARHATATKGVPATNPA 387
A P + +L +L S + +G LL R + T P + P+
Sbjct: 2359 AALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRT---PPSAPS 2415
Query: 388 PGKGTGSGLIGASGATMPTDTSKSEKLASRAVAPPTPASKRD-----------CVKGSAT 436
+ T P+ +S+ + S+++ PP R C+ T
Sbjct: 2416 QSRMTSE--------RAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTT 2467
Query: 437 P----------------------SGQESRTAPGEARKAATLPEMSAGEE----------- 463
P +G S APG P S G +
Sbjct: 2468 PVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPA 2527
Query: 464 -------------SSSSDSDPDSASPPSTGQNPSVSVQTSQDWKPTRSL 499
SSSS S S+S S+G + S S +S +P +L
Sbjct: 2528 KERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVAL 2576
Score = 32.3 bits (72), Expect = 1.1
Identities = 68/371 (18%), Positives = 124/371 (33%), Gaps = 11/371 (2%)
Query: 101 PSKSKSSSSSSSSTSSSSSSDEEDDSDLDAKRGPRGRETHPVPQKKAQILVAKPELKDPI 160
P +S S SS S+ ++ S+ D+ + + P+ Q+ + + K +
Sbjct: 1532 PLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRL 1591
Query: 161 RKKRGRKPLPPEQKATRRPVSLAKVLKTARKDLGAPASKLPPPLSAPVAGLAALKAHAKE 220
+R R PE K R A+ + + APA + P S + +
Sbjct: 1592 SPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEG 1651
Query: 221 ACGGPSAMATPENLASLMKGMASSPGRGGISWQSSIVHYMNRMTQSQAQAASRLALKAQA 280
+ S+ P + +G SSP S R + + +R A ++
Sbjct: 1652 SSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPP-----RRRSSRSSPELTRKARLSRR 1706
Query: 281 TNKCGLGLDLKVRTQKGELGMSPPGSKIPKAPSGGAVEQKVGNTGGPPHTHGASRVPAGC 340
+ + + RT S P S + ++ ++ T R P+
Sbjct: 1707 SRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPK 1766
Query: 341 P-GPQPAPTQELSLQVLDLQSVKNGMPGVGLLARHATATKGVPATNPAPGKGTGSGLIGA 399
P G Q + ++ + + R + T G GSG
Sbjct: 1767 PRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRG---GSGYHSR 1823
Query: 400 SGATMPTDTSKSEKLASRAVAPPTPASKRDCVKGSATP-SGQESRTAPGEARKAATLPEM 458
S A + + S + R+ PPT + KR + S P SR +P R++ + +
Sbjct: 1824 SPARQESSRTSSRRRRGRSRTPPT-SRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPL 1882
Query: 459 SAGEESSSSDS 469
+ S S S
Sbjct: 1883 ISRRRSRSRTS 1893
Score = 31.2 bits (69), Expect = 2.5
Identities = 88/448 (19%), Positives = 158/448 (35%), Gaps = 58/448 (12%)
Query: 76 PRGRPRKLTAMSSCSRRSKLKEPDAPSKSKSSSSSSSSTSSSSSSDEEDDSD-------L 128
P +P K++ +S S S P AP + SSS +S + S + D S +
Sbjct: 423 PSPQPTKVSRHASSSPESPKPAP-APGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRM 481
Query: 129 DAKRGP----RGRETHPVPQKKAQILVAKPE------------LKDPIRKKRGRKPLPPE 172
R P RGR P K+ P+ + P R+ R R P P
Sbjct: 482 GRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPG 541
Query: 173 QKATRRPVSLAKVLKTARKDLGAPASKLPPPLSAPVAGLAALKAHAKEACGGPSAMATPE 232
+R + ++AR+ G S+ P + A + ++ P+ +
Sbjct: 542 WSRSRNTQRRGR-SRSARR--GRSHSRSPATRGRSRSRTPARRGRSRSRT--PARRRSRS 596
Query: 233 NLASLMKGMASSPGRGGISWQSSIVHYMNRMTQSQAQAASRLALKAQATNKCGLGLDLKV 292
+ + + +P R G S + +R T+S + SR A+ + + +
Sbjct: 597 RTPTRRRSRSRTPARRGRSRSRTPARRRSR-TRSPVRRRSRSRSPARRSGRS----RSRT 651
Query: 293 RTQKGELGMSPPGSKIPKAPSGGAVEQKVGNTGGPPHTHGASRVPAGCPGPQPAPTQELS 352
++G P + ++ S + + P G SR P+ ++ S
Sbjct: 652 PARRGRSRSRTPARR-GRSRSRTPARRSGRSRSRTPARRGRSRSRT----PRRGRSRSRS 706
Query: 353 LQVLDLQSVKNGMPGVGLLARHATATKGVPATNPAPGKGTGSGLIGASGATMPTDTSKSE 412
L V+ G R + N K S S ++ S+
Sbjct: 707 L-------VRRGRSHSRTPQRRGRSGSSSERKN----KSRTSQRRSRSNSSPEMKKSRIS 755
Query: 413 KLASRAVAPPTPASK-----RDCVKGSATPSGQESRTAPGEARKAATLPEMSAGEESSSS 467
SR+++ P +K R + GS+ Q+S+T P +R ++ P+ + S
Sbjct: 756 SRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRS 815
Query: 468 DSDPDSASPPSTGQNPSVSVQTSQDWKP 495
S S+SPP ++ + S Q+ P
Sbjct: 816 RS---SSSPPPKQKSKTPSRQSHSSSSP 840
Score = 30.8 bits (68), Expect = 3.2
Identities = 30/110 (27%), Positives = 41/110 (37%), Gaps = 19/110 (17%)
Query: 383 ATNPAPGKGTGSGLIGASGATMPTDTSKSEKLASRAVAPPTPASKRDCVKGSATPSGQES 442
AT P+P S T P + + LA R P P + TP QE
Sbjct: 347 ATRPSPSPERSS--------TGPEPPAPTPLLAERHGGSPQPLA--------TTPLSQEP 390
Query: 443 RTAPGEARKAATLPEMSAGE---ESSSSDSDPDSASPPSTGQNPSVSVQT 489
P EA + E +SSSS+S P S P ++ S S ++
Sbjct: 391 VNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPES 440
Score = 29.6 bits (65), Expect = 7.2
Identities = 30/138 (21%), Positives = 52/138 (37%), Gaps = 10/138 (7%)
Query: 60 KKEHEKEVQNRKRGKRPRGRPRKLTAMSSCSRRSKLKEPDAPSKSKSSSSSSSSTSSSSS 119
++E +K + +K + RK + + S+R + S+S + + S S+S
Sbjct: 206 RRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTS 265
Query: 120 SDEEDDSDLDAKRGPRGRETHPVPQKKAQILVAKPELKDPIRKKRGRKPL-PPEQKATRR 178
+D SD R R + L + R+ G P P +T+R
Sbjct: 266 ADSASSSDTS-----RSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQR 320
Query: 179 PVSLAKVLKTARKDLGAP 196
P S +TA K +P
Sbjct: 321 PSS----PETATKQPSSP 334
Score = 29.6 bits (65), Expect = 7.2
Identities = 57/298 (19%), Positives = 98/298 (32%), Gaps = 38/298 (12%)
Query: 164 RGRKPLPPEQKATRRPVSLAKVLKTARKDLGAPASKLPPPLSAPVAGLAA--------LK 215
R R PP + R S ++R S LPP P + + + L
Sbjct: 2404 RARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLI 2463
Query: 216 AHAKEACGGPS----AMATPENLASLMKGMASSPGRGGISWQSSIVHYMNRMTQSQAQAA 271
A G S A+AT + A GM S P G Q A AA
Sbjct: 2464 AQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAA 2523
Query: 272 SRLALKAQATNKCGLGLDLKVRTQKGELGMSPPGSKIPKAPSGGAVEQKVGNTGGPPHTH 331
+ A + ++++ + S S + SG + G++
Sbjct: 2524 LQPAKERRSSSSS---------SSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEV 2574
Query: 332 GASRVPAGCPGPQPAPTQELSLQVLDLQSVKNGMPGVGLLA---RHATATKGVPATNPAP 388
RVP+ P P+ A V+ G P A R ++++ +++ +
Sbjct: 2575 ALKRVPSPTPAPKEA--------------VREGRPPEPTPAKRKRRSSSSSSSSSSSSSS 2620
Query: 389 GKGTGSGLIGASGATMPTDTSKSEKLASRAVAPPTPASKRDCVKGSATPSGQESRTAP 446
+ S +S ++ + +S S +S + A P P + P G+ +P
Sbjct: 2621 SSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSP 2678
>gi|116235487 chromodomain protein, Y-like 2 [Homo sapiens]
Length = 506
Score = 50.8 bits (120), Expect = 3e-06
Identities = 37/131 (28%), Positives = 60/131 (45%), Gaps = 4/131 (3%)
Query: 11 VFAAECILSKRL-RKGKLEYLVKWRGWSSKHNSWEPEENILDPRLLLAFQKKEHEKEVQN 69
++ E I+ KR +KGK EYL++W+G+ S ++WEPE ++L + H + +
Sbjct: 6 LYEVERIVDKRKNKKGKWEYLIRWKGYGSTEDTWEPEHHLLHCEEFIDEFNGLHMSKDKR 65
Query: 70 RKRGKRPRGRPRKLTAMSSCSRRSKLK-EPDAPSKSKSSSSSSSSTSSSSSSDEEDDSDL 128
K GK + KL S KL P P KSK +S + + ++ S
Sbjct: 66 IKSGK--QSSTSKLLRDSRGPSVEKLSHRPSDPGKSKGTSHKRKRINPPLAKPKKGYSGK 123
Query: 129 DAKRGPRGRET 139
+ G R +T
Sbjct: 124 PSSGGDRATKT 134
>gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens]
Length = 237
Score = 50.4 bits (119), Expect = 4e-06
Identities = 38/136 (27%), Positives = 72/136 (52%), Gaps = 6/136 (4%)
Query: 42 SWEPEENILDPRLLLAFQKKEHEKEVQNRKRGKRPRGRPRKLTAMSSCSRRSKLKEPDAP 101
+WE + L+ + + E E+++ + + + R + L+ S S++ + K+ +
Sbjct: 30 TWEEVKEQLEKKKKGSKALAEFEEKMNENWKKELEKHREKLLSGSESSSKKRQRKKKEKK 89
Query: 102 SKSKSSSSSSSST-SSSSSSDEEDDSDLDAKRGPRGRETHPVPQKKAQILVAKPE--LKD 158
+ SSSSSSS+ SSSSSSD ED+ D K+G R ++ K ++ +++ E KD
Sbjct: 90 KSGRYSSSSSSSSDSSSSSSDSEDE---DKKQGKRRKKKKNRSHKSSESSMSETESDSKD 146
Query: 159 PIRKKRGRKPLPPEQK 174
++KK+ K ++K
Sbjct: 147 SLKKKKKSKDGTEKEK 162
>gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens]
Length = 247
Score = 50.4 bits (119), Expect = 4e-06
Identities = 38/136 (27%), Positives = 72/136 (52%), Gaps = 6/136 (4%)
Query: 42 SWEPEENILDPRLLLAFQKKEHEKEVQNRKRGKRPRGRPRKLTAMSSCSRRSKLKEPDAP 101
+WE + L+ + + E E+++ + + + R + L+ S S++ + K+ +
Sbjct: 40 TWEEVKEQLEKKKKGSKALAEFEEKMNENWKKELEKHREKLLSGSESSSKKRQRKKKEKK 99
Query: 102 SKSKSSSSSSSST-SSSSSSDEEDDSDLDAKRGPRGRETHPVPQKKAQILVAKPE--LKD 158
+ SSSSSSS+ SSSSSSD ED+ D K+G R ++ K ++ +++ E KD
Sbjct: 100 KSGRYSSSSSSSSDSSSSSSDSEDE---DKKQGKRRKKKKNRSHKSSESSMSETESDSKD 156
Query: 159 PIRKKRGRKPLPPEQK 174
++KK+ K ++K
Sbjct: 157 SLKKKKKSKDGTEKEK 172
>gi|210032509 hypothetical protein LOC100130302 [Homo sapiens]
Length = 887
Score = 50.1 bits (118), Expect = 5e-06
Identities = 95/395 (24%), Positives = 139/395 (35%), Gaps = 86/395 (21%)
Query: 90 SRRSKLKEPDAPSKSKSSSSSSSSTSSSSSSDEEDDSDLDAKRGPRGRETHPVPQKKAQI 149
S +SK+K P S S S +S S SS + ++ D + + +G E HP P
Sbjct: 411 SVQSKVKGPGKMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKG-EKHPPP------ 463
Query: 150 LVAKPELKDPIRKKRGRKPLPPEQKAT--RRPVSLAKVLKTARKDLGAPASKLPPPLSAP 207
+ +L K PP+Q + +RP S A + A A A+ AP
Sbjct: 464 ---RTQLPSSSGKISSGNSFPPQQAGSPLKRPFSAAAAIAAAAAAAAAAAAAAAAAAPAP 520
Query: 208 VAGLAALKAHAKEACGGPSAMATPENLASLMKGMASSPGRGGISWQSSIVHYMNRMTQSQ 267
AA A A A +A A P + +A++P + S SQ
Sbjct: 521 ALAAAAAPALAAAAAPALAAAAAPAPAPAAAPAVAAAPAAAASAAPS----------HSQ 570
Query: 268 AQAASRLALKAQATNKCGLGLDLKVRTQKGELGMSPPGSKIPKAPSGGAVEQKVGNTG-- 325
+ + QA+ C PP I AP A++ + G+TG
Sbjct: 571 KPSVPLI----QASRPCP--------------AAQPPTKFIKIAP---AIQLRTGSTGLK 609
Query: 326 -----GP---PHTHGASRVPAGCPGP-QPAPTQELSLQVLDLQSVKNGMPGVGLLARHAT 376
GP G+S P PG PAP + DLQS +P
Sbjct: 610 AINVEGPVQGAQALGSSFKPVQAPGSGAPAPA---GISGSDLQSSGGPLPD--------A 658
Query: 377 ATKGVPATNPAPGK---GTGSGL-------IGASGATMPTDTSKSEKLAS-------RAV 419
V A++PAP + T GL + A + +S +L S A
Sbjct: 659 RPGAVQASSPAPLQFFLNTPEGLRPLTLLQVPQGSAVLTGPQQQSHQLVSLQQLQQPTAA 718
Query: 420 APPTPASKRDCV----KGSATPSGQESRTAPGEAR 450
PP P + + +G A P+ Q + P AR
Sbjct: 719 HPPQPGPQGSALGLSTQGQAFPAQQLLKVNPTRAR 753
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 48.9 bits (115), Expect = 1e-05
Identities = 85/354 (24%), Positives = 119/354 (33%), Gaps = 57/354 (16%)
Query: 165 GRKPLPPEQKATRRPVSLAKVLKTARKDLGAPASKLPPPLS------APVAGLAALKAHA 218
G P P + RRP+ A PA+KL PP APV AA+ A
Sbjct: 99 GGGPQRPGPPSPRRPLVPAGP--------APPAAKLRPPPEGSAGSCAPVPAAAAVAAGP 150
Query: 219 KEACGGPSAMATPENLASLM---------KGMASSPGRGGISWQSSIVHYMNRMTQSQAQ 269
+ A GP+ A P LA+ G PG+ + ++ + S
Sbjct: 151 EPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHA 210
Query: 270 AASRLALKAQATNKCGLGLDLKVRTQKGELGMSPP--GSKIPKAPSGGAVEQKVGNTGGP 327
AA ++L N L L G + +PP G+ P AP+ + P
Sbjct: 211 AAPAVSL---VNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPS----------P 257
Query: 328 PHTHGASRVPAGCPGPQPAPTQELSLQVLDLQSVKNGMPGVGLLARHATATKGVPATNPA 387
P + A P P PAP L+ P V A A PA
Sbjct: 258 PAAPAPAAPAAAPPPPPPAPA-TLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPA 316
Query: 388 PGKGTGSGLIGASGATMPTDTSKSEKLASRAVAPPTPASKRDCVKG--SATPSGQESRTA 445
P G +G+ G G A A P P K + K A P ++ A
Sbjct: 317 PAAGGPAGVSGQPG-------------PGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAA 363
Query: 446 PGEARKAATL---PEMSAGEESSSSDSDPDSASPPSTGQNPSVSVQTSQDWKPT 496
G A AA++ P M S ++ P +P + + +V S PT
Sbjct: 364 SGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPT 417
>gi|48255931 hepatoma-derived growth factor-related protein 2
isoform 1 [Homo sapiens]
Length = 671
Score = 48.5 bits (114), Expect = 1e-05
Identities = 38/107 (35%), Positives = 52/107 (48%), Gaps = 19/107 (17%)
Query: 64 EKEVQNRKRGKRPRGRPRKLTAMSSCSRRSKLKEPDAPSKSKSSSSSSSSTSSSSSSDEE 123
EK+ R + P G +K A S+ SK A + + + S+SS+SSSSSS
Sbjct: 207 EKKAAVRAPRRGPLGGRKKKKAPSASDSDSKADSDGAKPEPVAMARSASSSSSSSSSS-- 264
Query: 124 DDSDLDAKRGPRGRETHPVPQKKAQILVAKPELKDPIRKKRGRKPLP 170
DSD+ K+ PRGR+ P +K P+ K RGRKP P
Sbjct: 265 -DSDVSVKKPPRGRK----PAEK------------PLPKPRGRKPKP 294
Score = 46.6 bits (109), Expect = 6e-05
Identities = 36/127 (28%), Positives = 57/127 (44%), Gaps = 17/127 (13%)
Query: 61 KEHEKEVQNRKRGKRPRGRPRKLTAMSSCSRRSKLKEPDAPSKSKSSSSSSSSTSSSSSS 120
+E EKE + R+R + RG + + SS +L+E D P K + SSS S
Sbjct: 343 REQEKEEKERRRERADRGEAERGSGGSS---GDELREDDEPVKKRGRKGRGRGPPSSSDS 399
Query: 121 DEEDDSDLDAKRGPRGRETHPVPQKKAQILVAKPELKDPIRKKRGRKPLPPEQKATRRPV 180
+ E + + +AK+ KK Q +P K ++KR R PE+K +PV
Sbjct: 400 EPEAELEREAKKS----------AKKPQSSSTEPARKPGQKEKRVR----PEEKQQAKPV 445
Query: 181 SLAKVLK 187
+ + K
Sbjct: 446 KVERTRK 452
Score = 35.0 bits (79), Expect = 0.17
Identities = 44/149 (29%), Positives = 57/149 (38%), Gaps = 23/149 (15%)
Query: 78 GRPRKLTAMS-SCSRRSKLKEPDAPSKSKSSSSSSSSTSSSSSSDEEDDSDLD-----AK 131
G RK A+ S S+R++ D S S S +S SSS S++ D D A
Sbjct: 154 GLKRKTPALKMSVSKRARKASSDLDQASVSPSEEENS-ESSSESEKTSDQDFTPEKKAAV 212
Query: 132 RGPR-----GRETHPVP-----QKKAQILVAKPELKDPIRKKRGRKPLPPEQKATRRPVS 181
R PR GR+ P KA AKPE P+ R ++ VS
Sbjct: 213 RAPRRGPLGGRKKKKAPSASDSDSKADSDGAKPE---PVAMARSASSSSSSSSSSDSDVS 269
Query: 182 LAKV---LKTARKDLGAPASKLPPPLSAP 207
+ K K A K L P + P P P
Sbjct: 270 VKKPPRGRKPAEKPLPKPRGRKPKPERPP 298
>gi|14249158 hepatoma-derived growth factor-related protein 2
isoform 2 [Homo sapiens]
Length = 670
Score = 48.5 bits (114), Expect = 1e-05
Identities = 38/107 (35%), Positives = 52/107 (48%), Gaps = 19/107 (17%)
Query: 64 EKEVQNRKRGKRPRGRPRKLTAMSSCSRRSKLKEPDAPSKSKSSSSSSSSTSSSSSSDEE 123
EK+ R + P G +K A S+ SK A + + + S+SS+SSSSSS
Sbjct: 207 EKKAAVRAPRRGPLGGRKKKKAPSASDSDSKADSDGAKPEPVAMARSASSSSSSSSSS-- 264
Query: 124 DDSDLDAKRGPRGRETHPVPQKKAQILVAKPELKDPIRKKRGRKPLP 170
DSD+ K+ PRGR+ P +K P+ K RGRKP P
Sbjct: 265 -DSDVSVKKPPRGRK----PAEK------------PLPKPRGRKPKP 294
Score = 46.6 bits (109), Expect = 6e-05
Identities = 36/127 (28%), Positives = 57/127 (44%), Gaps = 17/127 (13%)
Query: 61 KEHEKEVQNRKRGKRPRGRPRKLTAMSSCSRRSKLKEPDAPSKSKSSSSSSSSTSSSSSS 120
+E EKE + R+R + RG + + SS +L+E D P K + SSS S
Sbjct: 343 REQEKEEKERRRERADRGEAERGSGGSS---GDELREDDEPVKKRGRKGRGRGPPSSSDS 399
Query: 121 DEEDDSDLDAKRGPRGRETHPVPQKKAQILVAKPELKDPIRKKRGRKPLPPEQKATRRPV 180
+ E + + +AK+ KK Q +P K ++KR R PE+K +PV
Sbjct: 400 EPEAELEREAKKS----------AKKPQSSSTEPARKPGQKEKRVR----PEEKQQAKPV 445
Query: 181 SLAKVLK 187
+ + K
Sbjct: 446 KVERTRK 452
Score = 35.0 bits (79), Expect = 0.17
Identities = 44/149 (29%), Positives = 57/149 (38%), Gaps = 23/149 (15%)
Query: 78 GRPRKLTAMS-SCSRRSKLKEPDAPSKSKSSSSSSSSTSSSSSSDEEDDSDLD-----AK 131
G RK A+ S S+R++ D S S S +S SSS S++ D D A
Sbjct: 154 GLKRKTPALKMSVSKRARKASSDLDQASVSPSEEENS-ESSSESEKTSDQDFTPEKKAAV 212
Query: 132 RGPR-----GRETHPVP-----QKKAQILVAKPELKDPIRKKRGRKPLPPEQKATRRPVS 181
R PR GR+ P KA AKPE P+ R ++ VS
Sbjct: 213 RAPRRGPLGGRKKKKAPSASDSDSKADSDGAKPE---PVAMARSASSSSSSSSSSDSDVS 269
Query: 182 LAKV---LKTARKDLGAPASKLPPPLSAP 207
+ K K A K L P + P P P
Sbjct: 270 VKKPPRGRKPAEKPLPKPRGRKPKPERPP 298
>gi|4507869 vasodilator-stimulated phosphoprotein [Homo sapiens]
Length = 380
Score = 47.8 bits (112), Expect = 3e-05
Identities = 44/162 (27%), Positives = 66/162 (40%), Gaps = 15/162 (9%)
Query: 317 VEQKVGNTGGPPHTHGASRVPAGCPGPQPAPTQELSLQVLDLQSVKNGMPGVGLLARHAT 376
+E++V N GGPP PAG P P P P G+P G+ A
Sbjct: 152 IERRVSNAGGPP------APPAGGPPPPPGPPPPPG------PPPPPGLPPSGVPAAAHG 199
Query: 377 ATKGVPATNPAP-GKGTGSGLIGASGATMPTDTSKSEKLASRAVAPPTP-ASKRDCVKGS 434
A G P P P +G G G GA G +K K++ + A P A K + +
Sbjct: 200 AGGGPPPAPPLPAAQGPGGGGAGAPGLAAAIAGAKLRKVSKQEEASGGPTAPKAESGRSG 259
Query: 435 ATPSGQESRTAPGEARKAATLPEMSAGEESSSSDSDPDSASP 476
+E RKA + E + +ES++ + +P++ P
Sbjct: 260 GGGLMEEMNAMLARRRKATQVGEKTPKDESANQE-EPEARVP 300
Score = 34.3 bits (77), Expect = 0.29
Identities = 42/175 (24%), Positives = 65/175 (37%), Gaps = 12/175 (6%)
Query: 303 PPGSKIPKAPSGGAVEQKVGNTGGPPHTHGASRVPAGCPGPQPAPTQELSLQVLDLQSVK 362
PPG P P G + +G P HGA P P P PA Q +
Sbjct: 173 PPG---PPPPPGPPPPPGLPPSGVPAAAHGAGGGPPPAP-PLPA-AQGPGGGGAGAPGLA 227
Query: 363 NGMPGVGL--LARHATATKGVPATNPAPGKGTGSGLIGASGATMPTDTSKSEKLASRAVA 420
+ G L +++ A+ G A G+ G GL+ A + ++ K
Sbjct: 228 AAIAGAKLRKVSKQEEASGGPTAPKAESGRSGGGGLMEEMNAML----ARRRKATQVGEK 283
Query: 421 PPTPASKRDCVKGSATPSGQESRTAPGEARKAATLPEMSAGEESSSSDSDPDSAS 475
P S + P+ ES P E + + TLP M + ++S++ P + S
Sbjct: 284 TPKDESANQEEPEARVPAQSESVRRPWE-KNSTTLPRMKSSSSVTTSETQPCTPS 337
>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
[Homo sapiens]
Length = 1488
Score = 47.8 bits (112), Expect = 3e-05
Identities = 97/456 (21%), Positives = 166/456 (36%), Gaps = 87/456 (19%)
Query: 59 QKKEHEKEVQNRKRGKRPRGRPRKLTAMSSCSRRSKLK--EPDAPSKSKSSSSSSSSTSS 116
++ + E+E + + K P G+ ++ A + ++ S K P P K+ S++ +
Sbjct: 873 EESDSEEEAETLAQVK-PSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDD 931
Query: 117 SSSSDEEDDSDLDAKRGPRGRETHPVPQKKAQILVAKPELKDPIRKKRGRKPLPPEQKAT 176
S SS EE DSD +A P AQ++ DP R G P + +A
Sbjct: 932 SGSSSEESDSDGEA----------PAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAA 981
Query: 177 RRPVSLAKVLKTARKDLG-------APASKLPPP-----------------LSAPVAGLA 212
P TAR PA++ P A +AG +
Sbjct: 982 STPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGAS 1041
Query: 213 ALKAHAKEACG----GPSAMATPENLASL-----------MKGMASSPGRGGISWQSSIV 257
+ K ++ + G GP+ + +N ASL K + P S +
Sbjct: 1042 SSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVD 1101
Query: 258 HYMNRMTQSQAQAASRLALKAQATNKCGLGLDLKVRTQKGELGMSPPGSKIPKAPSGGAV 317
+ + + Q+ S ++A+ TNK +K +L +K P++ S +
Sbjct: 1102 SAVGTLPATSPQSTS---VQAKGTNK----------LRKPKLPEVQQATKAPES-SDDSE 1147
Query: 318 EQKVGNTGGPPHTHGASRV-PAGCPGPQPAPTQELSLQVLDLQSVKNGM-PGVGLLARHA 375
+ ++G G A GP P+ T+ L + S + + P LL+ +
Sbjct: 1148 DSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYM 1207
Query: 376 TATKGVPATNPAPGKGTGSGLIGASGATMPTDTSKSEKLASRAVAPPTPASKRDC----V 431
T P PA + AS AT D+S S ++S A P K++
Sbjct: 1208 T-----PGLTPANSQ--------ASKATPKLDSSPS--VSSTLAAKDDPDGKQEAKPQQA 1252
Query: 432 KGSATPSGQESRTAPGEARKAATLPEMSAGEESSSS 467
G +P A G + + P+ AG +S+
Sbjct: 1253 AGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQAST 1288
Score = 44.3 bits (103), Expect = 3e-04
Identities = 84/379 (22%), Positives = 145/379 (38%), Gaps = 35/379 (9%)
Query: 91 RRSKLKEPDAPSKSKSSSSSSSSTSSSSSSDEEDDSDLDAKRGPRGRETHPVPQKKAQIL 150
R+ KL E +K+ SS S +S SSS EED GP+G K A L
Sbjct: 1126 RKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDG------EGPQG-------AKSAHTL 1172
Query: 151 VAKPELKDPIRKKRGRKPLPPEQKATRRPVSLAKVLKTARKDLGAPASKLPPPLSAPVAG 210
P + + ++ + + A + + L+ + + ASK P L + +
Sbjct: 1173 GPTPSRTETLVEETAAESSEDDVVAPSQSL-LSGYMTPGLTPANSQASKATPKLDSSPSV 1231
Query: 211 LAALKAHAKEACGGPSAMATPENLASLMKGMASSPGRGGISWQSSIVHYMNRMTQSQA-- 268
+ L AK+ G A P+ A ++ SP GG S +R + A
Sbjct: 1232 SSTLA--AKDDPDGKQE-AKPQQAAGML-----SPKTGGKEAASGTTPQKSRKPKKGAGN 1283
Query: 269 QAASRLALKAQATNKCGLGLDLKVRTQKGELGMSPPGSKIPKAPSGGAVEQKVGNTGGPP 328
AS LAL++ T +C LG + + + + +++ + +KV +T
Sbjct: 1284 PQASTLALQSNIT-QCLLGQPWPLNEAQVQASVVKVLTELLEQE-----RKKVVDTTKES 1337
Query: 329 HTHGASRVPAGCPGPQPAPTQELSLQVLDLQSVKNGMPGVGLLARHATATKGVPATNPAP 388
G G QPA S + L + + G V + +T +KG + A
Sbjct: 1338 SRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVS-PEKTSTTSKGKAKRDKAS 1396
Query: 389 G---KGTGSGLIGASGATMPTDTSKSEKLAS-RAVAPPTPASKRDCVKGSATPSGQESRT 444
G + G G +G+ GA + + + + P SK++ K +E +
Sbjct: 1397 GDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKE 1456
Query: 445 APGEARKAATLPEMSAGEE 463
+A+KA+T S ++
Sbjct: 1457 KKKKAKKASTKDSESPSQK 1475
Score = 43.9 bits (102), Expect = 4e-04
Identities = 101/468 (21%), Positives = 154/468 (32%), Gaps = 62/468 (13%)
Query: 62 EHEKEVQNRKRGKRPRGRPRKLTAMSSCSRRSKLKEPDAPSKSKSSSSSSSSTSSSSSSD 121
E E Q + GK P+ R A S + + P + + S SS
Sbjct: 420 EEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSS 479
Query: 122 EEDDSDLDAKRGPRGRETHPVPQKKAQILVAKPELKDPIRKKRGRKPLPPEQKATRRPV- 180
EE DSD +A + P+ K Q+ A P+ K G P+PP + P
Sbjct: 480 EESDSDREALAAMNAAQVKPLG-KSPQVKPASTMGMGPLGKGAG--PVPPGKVGPATPSA 536
Query: 181 --------SLAKVLKTARKDLGAPASKLPPPLSAPVAGLAALKAHAKEACGGPSAMATPE 232
S + +++ G + + P + + K + A G P
Sbjct: 537 QVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVA 596
Query: 233 NLASLMKGMASSPGRGGISWQSSIVHYMNRMTQSQAQAASRLALKAQATNKCGLGLDLKV 292
K M +S S + MT +QA+ A ++ K KV
Sbjct: 597 VQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKV 656
Query: 293 RT--------QKGELGMSPPGSKIPKAPSGG---------------AVEQKVGN--TGGP 327
+K SP GS A +GG + E+K G T G
Sbjct: 657 APVRVGTQAPRKAGTATSPAGSS--PAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQ 714
Query: 328 PHTHG------ASRVPA-GCPGPQPAP----------TQELSLQVLDLQSVKNGMPGVGL 370
+ G A+ VP G G AP TQ + + D +S +
Sbjct: 715 AKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEA 774
Query: 371 LARHATATKGVPAT----NPAPGKG-TGSGLIGASGATMPTDTSKSEKLASRAVAPPTPA 425
A A V T NPA + + G I A G + T +++++ + V PP
Sbjct: 775 AASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVV-TAAAQAKQRSPSKVKPPVRN 833
Query: 426 SKRDCVKGSATPSGQESRTAPGEARKAATLPEMSAGEESSSSDSDPDS 473
+ V S A A +A T PE +G SDS+ ++
Sbjct: 834 PQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEA 881
Score = 42.4 bits (98), Expect = 0.001
Identities = 97/415 (23%), Positives = 152/415 (36%), Gaps = 51/415 (12%)
Query: 87 SSCSRRSKLKEPDAPSKSKSSSSSSSSTSSSSSSDEEDDSDLDAKRGPRGRETHPVPQKK 146
S R+ K +E A K+ S STS SS +EE +++ AK PR T+
Sbjct: 57 SELGRKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAE-TAKATPRLASTNS-SVLG 114
Query: 147 AQILVAKPELKDPIRKKRGRKPLPPEQKATRRPVSLAKVLKTARKDLGAPASKLPPPLSA 206
A + + E +K G+ AT + V+ K+ RK A+ +
Sbjct: 115 ADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETE 174
Query: 207 PVAGLAALKAHAKEACGGPSAMATPENLASLMKGMASSPGRGGISWQSSI-VHYMNRMTQ 265
+ A A AK M + S + +SS + + S+ + +
Sbjct: 175 EEGSVPAFGAAAK------PGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSV 228
Query: 266 SQAQAASRLALKAQATNKCGLGLDLKVRTQKGELGMSPPGSKIPKAPSGGAVEQKVGNTG 325
S ++ +R A A A K G D+ + + G L P +K K P + + G
Sbjct: 229 STKESPARKA--APAPGKVG---DVTPQVKGGAL----PPAKRAKKPEEESESSEEG--- 276
Query: 326 GPPHTHGASRVPAGCPGPQPAPTQELSLQVLDLQSVKNGMPGVGLLARHATATKGVPATN 385
+ PAG A E LQV + G PG G AT P
Sbjct: 277 ----SESEEEAPAGTRSQVKA--SEKILQVRAASAPAKGTPGKG-------ATPAPPGKA 323
Query: 386 PAPGKGTGSGLIGASGATMPTDTSKSEK--LASRAVAPPTPASKRDCVKGSATPSGQESR 443
A T +G + ++S SE+ A++A+ + K V ++ P+ + R
Sbjct: 324 GAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPR 383
Query: 444 ----------TAPGEARKAATLPE---MSAGEESSSSDSDPDSASPPSTGQNPSV 485
T P A+ A E S+ EES S + P A P +G+ P V
Sbjct: 384 KGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKP--SGKAPQV 436
Score = 40.8 bits (94), Expect = 0.003
Identities = 93/459 (20%), Positives = 155/459 (33%), Gaps = 58/459 (12%)
Query: 68 QNRKRGKRPRGRPRKLTAMSSCSRRSKLKEPD-----APSKSKSSSSSSSSTSSSSSSDE 122
Q + GK P+ +P M + + P PS S +SS SSD
Sbjct: 496 QVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDS 555
Query: 123 EDDSDLDAKRGPRGRETHPVPQKKAQILVAK--PELKDPIRKK-RGRKPLPPEQKATRRP 179
D A + + + Q K AK P+ P+ + + KP+ + +
Sbjct: 556 SDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESS 615
Query: 180 VSL----AKVLKTARKDLGAPASKLPPPLSAPVAGLAALKAHAKEACGGPSAMATPENLA 235
S A TA + PA K+P + P A G A P
Sbjct: 616 DSADSEEAPAAMTAAQ--AKPALKIPQTKACPKKTNTTASAKVAPVRVGTQA---PRKAG 670
Query: 236 SLMKGMASSPGRGGISWQSSIVHYMNRMTQSQAQAASRLALKAQATNKCGLGLDLKVRTQ 295
+ SSP G + + + + + S+ + LA+ G GL +K +
Sbjct: 671 TATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTG-LAVTVGQAKSVGKGLQVKAASV 729
Query: 296 --KGELGMSP----PGSKIPK------------------------APSGGAVEQKVGNTG 325
KG LG PG P A S V+ V T
Sbjct: 730 PVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQ 789
Query: 326 GPPHTHGASRVPAGCPGPQPAPTQELSLQVLDLQSVKNGMPGVGLLARHATATKGVPATN 385
+ A+R P+ G AP + ++ Q + + +++T PA+
Sbjct: 790 AKANP-AAARAPSA-KGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASV 847
Query: 386 PAPGKGTGSGLIGASGATMPTDTSKSEKLA---SRAVAPPTPASKRDCVKGSATPSGQES 442
P+ GK + +G + +S+ E + + +A P+ K ++ + P+ +
Sbjct: 848 PSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESP 907
Query: 443 R-----TAPGEARKAATLPEMSAGEESSSSDSDPDSASP 476
R T PG+ +A SSS +SD D +P
Sbjct: 908 RKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAP 946
Score = 40.4 bits (93), Expect = 0.004
Identities = 102/462 (22%), Positives = 158/462 (34%), Gaps = 81/462 (17%)
Query: 59 QKKEHEKEVQNRKRGKRPRGRPRKLTAMSSCSRRSKLKEPDAPSKSKSSSSSSSSTSSSS 118
Q K EK +Q R +G P K + + + K + S SSS SS
Sbjct: 290 QVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSE--ESS 347
Query: 119 SSDEEDDSD---LDAKRGPRGRETHPVPQKKAQILVAKPELKDPIRKKRGRKPLPP---- 171
S+EE + L AK K +Q+ A K+ RK G P PP
Sbjct: 348 DSEEETPAAKALLQAK----------ASGKTSQVGAASAPAKESPRK--GAAPAPPGKTG 395
Query: 172 ----EQKATRRPVSLAKVLKTARKDLGAPASKLPPPLSAPVAGLAALKAHAKEACGGPSA 227
+ +A +R + + + APA P S + A A AKE+ +A
Sbjct: 396 PAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKP---SGKAPQVRAASAPAKESPRKGAA 452
Query: 228 MATPENLASLMKGMASSPGRGGISWQSSIVHYMNRMTQSQAQAASRLALKAQATNKCGLG 287
A P G A++ + G + S + +S + + A+ A G
Sbjct: 453 PAPPRK-----TGPAAAQVQVGKQEEDS----RSSSEESDSDREALAAMNAAQVKPLGKS 503
Query: 288 LDLKVRTQKG------ELGMSPPGSKIPKAPSG--GAVEQKVGNTGGPPHTHGASRVPAG 339
+K + G G PPG P PS G E+ ++ VP
Sbjct: 504 PQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTA 563
Query: 340 CPGPQPAPTQELSLQVLDLQSVKNGMPGVGLLARHATATKGVPATNPAPGKGTGSGLIGA 399
AP QE SL + P ++PA G +G +
Sbjct: 564 V-----APAQEKSL---------------------GNILQAKPTSSPAKGPPQKAGPVAV 597
Query: 400 S-GATMPTDTSKSEKLAS------RAVAPPTPASKRDCVKGSATPSGQESRTAPGEARKA 452
A P D S+S + +S A A T A + +K T + + A+ A
Sbjct: 598 QVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVA 657
Query: 453 ATLPEMSAGEESSSSDSDPDSASPPSTG--QNPSVSVQTSQD 492
A ++ ++ S P +SP G Q P+ +S++
Sbjct: 658 PVRVGTQAPRKAGTATS-PAGSSPAVAGGTQRPAEDSSSSEE 698
Score = 40.0 bits (92), Expect = 0.005
Identities = 112/483 (23%), Positives = 168/483 (34%), Gaps = 62/483 (12%)
Query: 37 SSKHNSWEPEENILDPRLLLAFQKKEHEKEVQNRKRGKRPRGRPRKLTAMSSCSRRSKLK 96
SS S + EE + LL Q K K Q + PRK A + K
Sbjct: 341 SSSEESSDSEEETPAAKALL--QAKASGKTSQVGAASAPAKESPRKGAAPAPPG-----K 393
Query: 97 EPDAPSKSKSSSSSSSSTSSSSSSDEEDDSDLDAKRGPRGRETHPVPQKKAQILVAKPEL 156
A +K+++ S SSS SD E+++ AK P G+ PQ +A AK
Sbjct: 394 TGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAK--PSGK----APQVRAASAPAKES- 446
Query: 157 KDPIRKKRGRKPLPPEQ-----------KATRRPVSLAKVLKTARKDLGA-------PAS 198
++G P PP + K S ++ + R+ L A P
Sbjct: 447 -----PRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLG 501
Query: 199 KLPPPLSAPVAGLAALKAHAKEACGGPSAMATPENLASLMKGMASSPGRGGISWQSSIVH 258
K P A G+ L A G ATP A + K S S SS
Sbjct: 502 KSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPS--AQVGKWEEDSESSSEESSDSSDGE 559
Query: 259 YMNRMTQSQAQAASRLALKAQATNKCGLGLDLK---VRTQ-KGELGMSPPGSKIPKAPSG 314
+ +Q ++ + L+A+ T+ G K V Q K E M S + S
Sbjct: 560 VPTAVAPAQEKSLGNI-LQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSA 618
Query: 315 GAVEQKVGNTGGPPHTHGASRVPAGCPGPQPAPTQELSLQVLDLQSVKNGMPGVGLLARH 374
+ E T A ++P P+ T S K VG A
Sbjct: 619 DSEEAPAAMTAA--QAKPALKIPQTKACPKKTNTTA---------SAKVAPVRVGTQAPR 667
Query: 375 ATATKGVPA-TNPAPGKGTGSGLIGASGATMPTDTSKSEKLASRAVAPPTPASKRDCVKG 433
T PA ++PA GT +S + +D+ + + + V K VK
Sbjct: 668 KAGTATSPAGSSPAVAGGTQRPAEDSSSSE-ESDSEEEKTGLAVTVGQAKSVGKGLQVKA 726
Query: 434 SATPS----GQESRTA-PGEARKAATLPEMSAGEESSSSDSDPDSASPPSTGQNPSVSVQ 488
++ P GQ + PG+ T + E+S SS+ + DS ++ SV+
Sbjct: 727 ASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVK 786
Query: 489 TSQ 491
+Q
Sbjct: 787 KTQ 789
Score = 33.9 bits (76), Expect = 0.38
Identities = 38/160 (23%), Positives = 67/160 (41%), Gaps = 14/160 (8%)
Query: 53 RLLLAFQKKEHEKEVQNRKRGKRP--RGRPRKLTAMSSCSR--RSKLKEPDAPSKSKSSS 108
++L ++E +K V K R R RKL+ +R RSK K+ + +S
Sbjct: 1317 KVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEAS 1376
Query: 109 SSSSSTSSSSSSDEEDD---SDLDAKR-----GPRGRETHPVPQ-KKAQILVAKPELKDP 159
S TS++S + D D+ K+ G +G + P + +K V + +P
Sbjct: 1377 VSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNP 1436
Query: 160 IRKKRGRKPLPPEQKATRRPVSLAKVLKTARKDLGAPASK 199
+ K+ +K +K + K K + KD +P+ K
Sbjct: 1437 -KSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQK 1475
>gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b [Homo
sapiens]
Length = 1411
Score = 47.8 bits (112), Expect = 3e-05
Identities = 97/456 (21%), Positives = 166/456 (36%), Gaps = 87/456 (19%)
Query: 59 QKKEHEKEVQNRKRGKRPRGRPRKLTAMSSCSRRSKLK--EPDAPSKSKSSSSSSSSTSS 116
++ + E+E + + K P G+ ++ A + ++ S K P P K+ S++ +
Sbjct: 796 EESDSEEEAETLAQVK-PSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDD 854
Query: 117 SSSSDEEDDSDLDAKRGPRGRETHPVPQKKAQILVAKPELKDPIRKKRGRKPLPPEQKAT 176
S SS EE DSD +A P AQ++ DP R G P + +A
Sbjct: 855 SGSSSEESDSDGEA----------PAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAA 904
Query: 177 RRPVSLAKVLKTARKDLG-------APASKLPPP-----------------LSAPVAGLA 212
P TAR PA++ P A +AG +
Sbjct: 905 STPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGAS 964
Query: 213 ALKAHAKEACG----GPSAMATPENLASL-----------MKGMASSPGRGGISWQSSIV 257
+ K ++ + G GP+ + +N ASL K + P S +
Sbjct: 965 SSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVD 1024
Query: 258 HYMNRMTQSQAQAASRLALKAQATNKCGLGLDLKVRTQKGELGMSPPGSKIPKAPSGGAV 317
+ + + Q+ S ++A+ TNK +K +L +K P++ S +
Sbjct: 1025 SAVGTLPATSPQSTS---VQAKGTNK----------LRKPKLPEVQQATKAPES-SDDSE 1070
Query: 318 EQKVGNTGGPPHTHGASRV-PAGCPGPQPAPTQELSLQVLDLQSVKNGM-PGVGLLARHA 375
+ ++G G A GP P+ T+ L + S + + P LL+ +
Sbjct: 1071 DSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYM 1130
Query: 376 TATKGVPATNPAPGKGTGSGLIGASGATMPTDTSKSEKLASRAVAPPTPASKRDC----V 431
T P PA + AS AT D+S S ++S A P K++
Sbjct: 1131 T-----PGLTPANSQ--------ASKATPKLDSSPS--VSSTLAAKDDPDGKQEAKPQQA 1175
Query: 432 KGSATPSGQESRTAPGEARKAATLPEMSAGEESSSS 467
G +P A G + + P+ AG +S+
Sbjct: 1176 AGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQAST 1211
Score = 44.3 bits (103), Expect = 3e-04
Identities = 84/379 (22%), Positives = 145/379 (38%), Gaps = 35/379 (9%)
Query: 91 RRSKLKEPDAPSKSKSSSSSSSSTSSSSSSDEEDDSDLDAKRGPRGRETHPVPQKKAQIL 150
R+ KL E +K+ SS S +S SSS EED GP+G K A L
Sbjct: 1049 RKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDG------EGPQG-------AKSAHTL 1095
Query: 151 VAKPELKDPIRKKRGRKPLPPEQKATRRPVSLAKVLKTARKDLGAPASKLPPPLSAPVAG 210
P + + ++ + + A + + L+ + + ASK P L + +
Sbjct: 1096 GPTPSRTETLVEETAAESSEDDVVAPSQSL-LSGYMTPGLTPANSQASKATPKLDSSPSV 1154
Query: 211 LAALKAHAKEACGGPSAMATPENLASLMKGMASSPGRGGISWQSSIVHYMNRMTQSQA-- 268
+ L AK+ G A P+ A ++ SP GG S +R + A
Sbjct: 1155 SSTLA--AKDDPDGKQE-AKPQQAAGML-----SPKTGGKEAASGTTPQKSRKPKKGAGN 1206
Query: 269 QAASRLALKAQATNKCGLGLDLKVRTQKGELGMSPPGSKIPKAPSGGAVEQKVGNTGGPP 328
AS LAL++ T +C LG + + + + +++ + +KV +T
Sbjct: 1207 PQASTLALQSNIT-QCLLGQPWPLNEAQVQASVVKVLTELLEQE-----RKKVVDTTKES 1260
Query: 329 HTHGASRVPAGCPGPQPAPTQELSLQVLDLQSVKNGMPGVGLLARHATATKGVPATNPAP 388
G G QPA S + L + + G V + +T +KG + A
Sbjct: 1261 SRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVS-PEKTSTTSKGKAKRDKAS 1319
Query: 389 G---KGTGSGLIGASGATMPTDTSKSEKLAS-RAVAPPTPASKRDCVKGSATPSGQESRT 444
G + G G +G+ GA + + + + P SK++ K +E +
Sbjct: 1320 GDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKE 1379
Query: 445 APGEARKAATLPEMSAGEE 463
+A+KA+T S ++
Sbjct: 1380 KKKKAKKASTKDSESPSQK 1398
Score = 43.9 bits (102), Expect = 4e-04
Identities = 101/468 (21%), Positives = 154/468 (32%), Gaps = 62/468 (13%)
Query: 62 EHEKEVQNRKRGKRPRGRPRKLTAMSSCSRRSKLKEPDAPSKSKSSSSSSSSTSSSSSSD 121
E E Q + GK P+ R A S + + P + + S SS
Sbjct: 343 EEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSS 402
Query: 122 EEDDSDLDAKRGPRGRETHPVPQKKAQILVAKPELKDPIRKKRGRKPLPPEQKATRRPV- 180
EE DSD +A + P+ K Q+ A P+ K G P+PP + P
Sbjct: 403 EESDSDREALAAMNAAQVKPLG-KSPQVKPASTMGMGPLGKGAG--PVPPGKVGPATPSA 459
Query: 181 --------SLAKVLKTARKDLGAPASKLPPPLSAPVAGLAALKAHAKEACGGPSAMATPE 232
S + +++ G + + P + + K + A G P
Sbjct: 460 QVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVA 519
Query: 233 NLASLMKGMASSPGRGGISWQSSIVHYMNRMTQSQAQAASRLALKAQATNKCGLGLDLKV 292
K M +S S + MT +QA+ A ++ K KV
Sbjct: 520 VQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKV 579
Query: 293 RT--------QKGELGMSPPGSKIPKAPSGG---------------AVEQKVGN--TGGP 327
+K SP GS A +GG + E+K G T G
Sbjct: 580 APVRVGTQAPRKAGTATSPAGSS--PAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQ 637
Query: 328 PHTHG------ASRVPA-GCPGPQPAP----------TQELSLQVLDLQSVKNGMPGVGL 370
+ G A+ VP G G AP TQ + + D +S +
Sbjct: 638 AKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEA 697
Query: 371 LARHATATKGVPAT----NPAPGKG-TGSGLIGASGATMPTDTSKSEKLASRAVAPPTPA 425
A A V T NPA + + G I A G + T +++++ + V PP
Sbjct: 698 AASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVV-TAAAQAKQRSPSKVKPPVRN 756
Query: 426 SKRDCVKGSATPSGQESRTAPGEARKAATLPEMSAGEESSSSDSDPDS 473
+ V S A A +A T PE +G SDS+ ++
Sbjct: 757 PQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEA 804
Score = 42.0 bits (97), Expect = 0.001
Identities = 110/508 (21%), Positives = 181/508 (35%), Gaps = 85/508 (16%)
Query: 37 SSKHNSWEPEENILDPRLLLAFQKKEHEKEVQNRKRGKRPRGRPRKLTAMSSCSRRSKLK 96
SS S + EE + LL Q K K Q + PRK A + K
Sbjct: 264 SSSEESSDSEEETPAAKALL--QAKASGKTSQVGAASAPAKESPRKGAAPAPPG-----K 316
Query: 97 EPDAPSKSKSSSSSSSSTSSSSSSDEEDDSDLDAK---RGPRGRETH------------P 141
A +K+++ S SSS SD E+++ AK + P+ R P
Sbjct: 317 TGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAP 376
Query: 142 VPQKK-----AQILVAKPELKDPIRKKRG---RKPLPPEQKATRRPVSLAKVLKTARK-- 191
P +K AQ+ V K E + R+ L A +P+ + +K A
Sbjct: 377 APPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMG 436
Query: 192 --DLGAPASKLPPPLSAPVAGLAAL-------KAHAKEACGG-----PSAMATPE--NLA 235
LG A +PP P A + ++ ++E+ P+A+A + +L
Sbjct: 437 MGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLG 496
Query: 236 SLMKGM-ASSPGR------GGISWQSSIVHYMNRMTQSQAQAASRLALKAQATNKCGLGL 288
++++ SSP + G ++ Q M+ S+ + S + +A A
Sbjct: 497 NILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAK 556
Query: 289 D-LKVRTQKG--ELGMSPPGSKIPKAPSGGAVEQKVGNTGGPPHTHGASRVPAGCPGPQP 345
LK+ K + + +K+ G +K G P A PA G Q
Sbjct: 557 PALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSP-----AGSSPAVAGGTQR 611
Query: 346 APTQELSLQVLDLQSVKNGMP---------GVGLLARHATATKGVPATNPAPGKGTGSGL 396
S + D + K G+ G GL + A+ VP + G+GT L
Sbjct: 612 PAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAAS----VPVKG-SLGQGTAPVL 666
Query: 397 IGASGATM-------PTDTSKSEKLASRAVAPPTPASKRDCVKGSATPSGQESRTAPGEA 449
G +G T+ D+ SE+ + A +PA + VK + + + AP A
Sbjct: 667 PGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAP-SA 725
Query: 450 RKAATLPEMSAGEESSSSDSDPDSASPP 477
+ + P + + P PP
Sbjct: 726 KGTISAPGKVVTAAAQAKQRSPSKVKPP 753
Score = 40.8 bits (94), Expect = 0.003
Identities = 93/459 (20%), Positives = 155/459 (33%), Gaps = 58/459 (12%)
Query: 68 QNRKRGKRPRGRPRKLTAMSSCSRRSKLKEPD-----APSKSKSSSSSSSSTSSSSSSDE 122
Q + GK P+ +P M + + P PS S +SS SSD
Sbjct: 419 QVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDS 478
Query: 123 EDDSDLDAKRGPRGRETHPVPQKKAQILVAK--PELKDPIRKK-RGRKPLPPEQKATRRP 179
D A + + + Q K AK P+ P+ + + KP+ + +
Sbjct: 479 SDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESS 538
Query: 180 VSL----AKVLKTARKDLGAPASKLPPPLSAPVAGLAALKAHAKEACGGPSAMATPENLA 235
S A TA + PA K+P + P A G A P
Sbjct: 539 DSADSEEAPAAMTAAQ--AKPALKIPQTKACPKKTNTTASAKVAPVRVGTQA---PRKAG 593
Query: 236 SLMKGMASSPGRGGISWQSSIVHYMNRMTQSQAQAASRLALKAQATNKCGLGLDLKVRTQ 295
+ SSP G + + + + + S+ + LA+ G GL +K +
Sbjct: 594 TATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTG-LAVTVGQAKSVGKGLQVKAASV 652
Query: 296 --KGELGMSP----PGSKIPK------------------------APSGGAVEQKVGNTG 325
KG LG PG P A S V+ V T
Sbjct: 653 PVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQ 712
Query: 326 GPPHTHGASRVPAGCPGPQPAPTQELSLQVLDLQSVKNGMPGVGLLARHATATKGVPATN 385
+ A+R P+ G AP + ++ Q + + +++T PA+
Sbjct: 713 AKANP-AAARAPSA-KGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASV 770
Query: 386 PAPGKGTGSGLIGASGATMPTDTSKSEKLA---SRAVAPPTPASKRDCVKGSATPSGQES 442
P+ GK + +G + +S+ E + + +A P+ K ++ + P+ +
Sbjct: 771 PSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESP 830
Query: 443 R-----TAPGEARKAATLPEMSAGEESSSSDSDPDSASP 476
R T PG+ +A SSS +SD D +P
Sbjct: 831 RKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAP 869
Score = 39.3 bits (90), Expect = 0.009
Identities = 101/460 (21%), Positives = 157/460 (34%), Gaps = 81/460 (17%)
Query: 61 KEHEKEVQNRKRGKRPRGRPRKLTAMSSCSRRSKLKEPDAPSKSKSSSSSSSSTSSSSSS 120
K EK +Q R +G P K + + + K + S SSS SS S
Sbjct: 215 KASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSE--ESSDS 272
Query: 121 DEEDDSD---LDAKRGPRGRETHPVPQKKAQILVAKPELKDPIRKKRGRKPLPP------ 171
+EE + L AK K +Q+ A K+ RK G P PP
Sbjct: 273 EEETPAAKALLQAK----------ASGKTSQVGAASAPAKESPRK--GAAPAPPGKTGPA 320
Query: 172 --EQKATRRPVSLAKVLKTARKDLGAPASKLPPPLSAPVAGLAALKAHAKEACGGPSAMA 229
+ +A +R + + + APA P S + A A AKE+ +A A
Sbjct: 321 VAKAQAGKREEDSQSSSEESDSEEEAPAQAKP---SGKAPQVRAASAPAKESPRKGAAPA 377
Query: 230 TPENLASLMKGMASSPGRGGISWQSSIVHYMNRMTQSQAQAASRLALKAQATNKCGLGLD 289
P G A++ + G + S + +S + + A+ A G
Sbjct: 378 PPRK-----TGPAAAQVQVGKQEEDS----RSSSEESDSDREALAAMNAAQVKPLGKSPQ 428
Query: 290 LKVRTQKG------ELGMSPPGSKIPKAPSG--GAVEQKVGNTGGPPHTHGASRVPAGCP 341
+K + G G PPG P PS G E+ ++ VP
Sbjct: 429 VKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAV- 487
Query: 342 GPQPAPTQELSLQVLDLQSVKNGMPGVGLLARHATATKGVPATNPAPGKGTGSGLIGAS- 400
AP QE SL + P ++PA G +G +
Sbjct: 488 ----APAQEKSL---------------------GNILQAKPTSSPAKGPPQKAGPVAVQV 522
Query: 401 GATMPTDTSKSEKLAS------RAVAPPTPASKRDCVKGSATPSGQESRTAPGEARKAAT 454
A P D S+S + +S A A T A + +K T + + A+ A
Sbjct: 523 KAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPV 582
Query: 455 LPEMSAGEESSSSDSDPDSASPPSTG--QNPSVSVQTSQD 492
A ++ ++ S P +SP G Q P+ +S++
Sbjct: 583 RVGTQAPRKAGTATS-PAGSSPAVAGGTQRPAEDSSSSEE 621
Score = 33.9 bits (76), Expect = 0.38
Identities = 38/160 (23%), Positives = 67/160 (41%), Gaps = 14/160 (8%)
Query: 53 RLLLAFQKKEHEKEVQNRKRGKRP--RGRPRKLTAMSSCSR--RSKLKEPDAPSKSKSSS 108
++L ++E +K V K R R RKL+ +R RSK K+ + +S
Sbjct: 1240 KVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEAS 1299
Query: 109 SSSSSTSSSSSSDEEDD---SDLDAKR-----GPRGRETHPVPQ-KKAQILVAKPELKDP 159
S TS++S + D D+ K+ G +G + P + +K V + +P
Sbjct: 1300 VSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNP 1359
Query: 160 IRKKRGRKPLPPEQKATRRPVSLAKVLKTARKDLGAPASK 199
+ K+ +K +K + K K + KD +P+ K
Sbjct: 1360 -KSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQK 1398
Score = 31.6 bits (70), Expect = 1.9
Identities = 46/190 (24%), Positives = 62/190 (32%), Gaps = 25/190 (13%)
Query: 294 TQKGELGMSPPGSKIPKAPSGGAVEQKVGNTGGP-PHTHGASRVPAGCPGPQPAPTQELS 352
T LG P S KA A +K G TG PH V G P + E S
Sbjct: 108 TNSSVLGADLPSSMKEKAK---AETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPS 164
Query: 353 LQVLDLQSVKN--GMPGVGLLARHATATKGVPATNPAPGKGTGSGLIGASGATMPTDTSK 410
+ + +P G A+ P A + S +S +
Sbjct: 165 ANTTLVSETEEEGSVPAFGAAAK--------PGMVSAGQADSSSEDTSSSSDETDVEVKA 216
Query: 411 SEKLAS-RAVAPPTPASKRDCVKGSATPSGQESRTAPGEARKAATLPEMSAGEESSSSDS 469
SEK+ RA + P TP + PG+A A+ + EE S S S
Sbjct: 217 SEKILQVRAASAPA----------KGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSS 266
Query: 470 DPDSASPPST 479
+ S S T
Sbjct: 267 EESSDSEEET 276
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.307 0.124 0.354
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,654,922
Number of Sequences: 37866
Number of extensions: 1421285
Number of successful extensions: 17302
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 340
Number of HSP's successfully gapped in prelim test: 939
Number of HSP's that attempted gapping in prelim test: 10741
Number of HSP's gapped (non-prelim): 4963
length of query: 532
length of database: 18,247,518
effective HSP length: 107
effective length of query: 425
effective length of database: 14,195,856
effective search space: 6033238800
effective search space used: 6033238800
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.