BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|61175239 transcription elongation factor A (SII)-like 5 [Homo sapiens] (206 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|61175239 transcription elongation factor A (SII)-like 5 [Homo... 427 e-120 gi|55749431 transcription elongation factor A (SII)-like 3 [Homo... 376 e-105 gi|14249718 transcription elongation factor A (SII)-like 3 [Homo... 376 e-105 gi|118600971 transcription elongation factor A (SII)-like 6 [Hom... 323 5e-89 gi|17933774 transcription elongation factor A (SII)-like 2 [Homo... 185 2e-47 gi|55749459 transcription elongation factor A (SII)-like 4 [Homo... 184 4e-47 gi|55749442 transcription elongation factor A (SII)-like 4 [Homo... 184 4e-47 gi|65505873 transcription elongation factor A (SII)-like 4 [Homo... 184 4e-47 gi|55749451 transcription elongation factor A (SII)-like 4 [Homo... 184 4e-47 gi|4759128 solute carrier family 24 (sodium/potassium/calcium ex... 65 4e-11 gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 64 9e-11 gi|21361639 DIPB protein [Homo sapiens] 59 2e-09 gi|55956788 nucleolin [Homo sapiens] 58 6e-09 gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 56 2e-08 gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 56 2e-08 gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 56 2e-08 gi|13540523 nucleosomal binding protein 1 [Homo sapiens] 56 2e-08 gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 55 4e-08 gi|55749466 transcription elongation factor A (SII)-like 8 [Homo... 54 9e-08 gi|23503247 transcription elongation factor A (SII)-like 8 [Homo... 54 9e-08 gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 53 2e-07 gi|20270337 Leo1, Paf1/RNA polymerase II complex component, homo... 52 5e-07 gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 51 6e-07 gi|239747174 PREDICTED: hypothetical protein XP_002343931, parti... 51 6e-07 gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 51 6e-07 gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 51 6e-07 gi|115529449 upstream binding transcription factor, RNA polymera... 50 1e-06 gi|115529451 upstream binding transcription factor, RNA polymera... 50 1e-06 gi|7657671 upstream binding transcription factor, RNA polymerase... 50 1e-06 gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 49 2e-06 >gi|61175239 transcription elongation factor A (SII)-like 5 [Homo sapiens] Length = 206 Score = 427 bits (1099), Expect = e-120 Identities = 206/206 (100%), Positives = 206/206 (100%) Query: 1 MEKLYKENEGKPENERNLESEGKPEDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEGEP 60 MEKLYKENEGKPENERNLESEGKPEDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEGEP Sbjct: 1 MEKLYKENEGKPENERNLESEGKPEDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEGEP 60 Query: 61 GDEGQLEDEGNQEKQGKSEGEDKPQSEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKT 120 GDEGQLEDEGNQEKQGKSEGEDKPQSEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKT Sbjct: 61 GDEGQLEDEGNQEKQGKSEGEDKPQSEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKT 120 Query: 121 DRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRDVQDPFA 180 DRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRDVQDPFA Sbjct: 121 DRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRDVQDPFA 180 Query: 181 PRGQRGVRGVRGGGRGQKDLEDVPYV 206 PRGQRGVRGVRGGGRGQKDLEDVPYV Sbjct: 181 PRGQRGVRGVRGGGRGQKDLEDVPYV 206 >gi|55749431 transcription elongation factor A (SII)-like 3 [Homo sapiens] Length = 200 Score = 376 bits (966), Expect = e-105 Identities = 182/206 (88%), Positives = 191/206 (92%), Gaps = 6/206 (2%) Query: 1 MEKLYKENEGKPENERNLESEGKPEDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEGEP 60 MEK Y +NEG NLE+EGKPEDE +DEGKSDEEEKPD+EGKTECEGKREDEGEP Sbjct: 1 MEKPYNKNEG------NLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEP 54 Query: 61 GDEGQLEDEGNQEKQGKSEGEDKPQSEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKT 120 GDEGQLEDEG+QEKQG+SEGE KPQ EGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKT Sbjct: 55 GDEGQLEDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKT 114 Query: 121 DRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRDVQDPFA 180 DRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRDVQDPFA Sbjct: 115 DRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRDVQDPFA 174 Query: 181 PRGQRGVRGVRGGGRGQKDLEDVPYV 206 PRGQRGVRGVRGGGRGQ+ L D+PY+ Sbjct: 175 PRGQRGVRGVRGGGRGQRGLHDIPYL 200 >gi|14249718 transcription elongation factor A (SII)-like 3 [Homo sapiens] Length = 200 Score = 376 bits (966), Expect = e-105 Identities = 182/206 (88%), Positives = 191/206 (92%), Gaps = 6/206 (2%) Query: 1 MEKLYKENEGKPENERNLESEGKPEDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEGEP 60 MEK Y +NEG NLE+EGKPEDE +DEGKSDEEEKPD+EGKTECEGKREDEGEP Sbjct: 1 MEKPYNKNEG------NLENEGKPEDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEP 54 Query: 61 GDEGQLEDEGNQEKQGKSEGEDKPQSEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKT 120 GDEGQLEDEG+QEKQG+SEGE KPQ EGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKT Sbjct: 55 GDEGQLEDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKT 114 Query: 121 DRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRDVQDPFA 180 DRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRDVQDPFA Sbjct: 115 DRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRDVQDPFA 174 Query: 181 PRGQRGVRGVRGGGRGQKDLEDVPYV 206 PRGQRGVRGVRGGGRGQ+ L D+PY+ Sbjct: 175 PRGQRGVRGVRGGGRGQRGLHDIPYL 200 >gi|118600971 transcription elongation factor A (SII)-like 6 [Homo sapiens] Length = 183 Score = 323 bits (829), Expect = 5e-89 Identities = 161/189 (85%), Positives = 168/189 (88%), Gaps = 7/189 (3%) Query: 1 MEKLYKENEGKPENERNLESEGKPEDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEGEP 60 MEK Y +NEG NLE+EGKPEDE +DEGKSDEEEKPD EGKTECEGKR+ EGEP Sbjct: 1 MEKPYNKNEG------NLENEGKPEDEVEPDDEGKSDEEEKPDAEGKTECEGKRKAEGEP 54 Query: 61 GDEGQLEDEGNQEKQGKSEGEDKPQSEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKT 120 GDEGQLED+G+QEKQGKSEGE KPQ EGKPASQAKPE QPRAAEKRPA DYVPRKAKRKT Sbjct: 55 GDEGQLEDKGSQEKQGKSEGEGKPQGEGKPASQAKPEGQPRAAEKRPAGDYVPRKAKRKT 114 Query: 121 DRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRDVQDPFA 180 DRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRDVQDPFA Sbjct: 115 DRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRDVQDPFA 174 Query: 181 PRGQRGVRG 189 +G GV G Sbjct: 175 -QGDNGVSG 182 >gi|17933774 transcription elongation factor A (SII)-like 2 [Homo sapiens] Length = 227 Score = 185 bits (470), Expect = 2e-47 Identities = 103/229 (44%), Positives = 147/229 (64%), Gaps = 25/229 (10%) Query: 1 MEKLYKENEGKPENERNLESE------GKPE-----------DEGSTEDEGKSDEE---- 39 MEKL+ ENEG P N+ +++E GKPE +EG+TE+ GK EE Sbjct: 1 MEKLFNENEGMPSNQGKIDNEEQPPHEGKPEVACILEDKKLENEGNTENTGKRVEEPLKD 60 Query: 40 -EKPDMEGKTECEGKREDEGEPGDEGQLEDEGNQEKQGKSEGEDKPQSEGKPASQAKPES 98 EKP+ GK + EGK E +G+ +G + EG E+ G++EGE +P SE +P S+ +PES Sbjct: 61 KEKPESAGKAKGEGKSERKGKSEMQGGSKTEGKPERGGRAEGEGEPDSEREPESEGEPES 120 Query: 99 QPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEE 158 + RAA KRPAED +PRKAKRKT++G K +E + + + S+E+M+RE +++R +++ Sbjct: 121 ETRAAGKRPAEDDIPRKAKRKTNKGLAQYLKQYKEAIHDMNFSNEDMIREFDNMARVEDK 180 Query: 159 LRK-KQKMGGFHWMQRDVQDPFAPRGQRGVRGVRGGGRGQKDLEDVPYV 206 RK KQK+G F WMQR++QDPF PRG R RG G ++D ED+PYV Sbjct: 181 RRKSKQKLGAFLWMQRNLQDPFYPRGPREFRG--GCRAPRRDTEDIPYV 227 >gi|55749459 transcription elongation factor A (SII)-like 4 [Homo sapiens] Length = 215 Score = 184 bits (468), Expect = 4e-47 Identities = 100/217 (46%), Positives = 143/217 (65%), Gaps = 13/217 (5%) Query: 1 MEKLYKENEGKPENERNLESEGKPEDEGSTE-----DEGKSDEEEKPDMEGKTECEGKRE 55 MEKLY ENEG N+ +E+E +P+DE E ++ K + E K + +GKT E + Sbjct: 1 MEKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLK 60 Query: 56 DEGEPGDEGQLED-----EGNQEKQGKSEGEDKPQSEGKPASQAKPESQPRAAEKRPAED 110 D+G+P EG+ ++ EG E +G SE E KP+ EGKP S+ +P S+ RAA KRPAED Sbjct: 61 DKGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAED 120 Query: 111 YVPRKAKRKTDRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRK-KQKMGGFH 169 VPRKAKRKT++G K+ +E + + + S+E+M+RE ++++ Q+E RK KQK+G F Sbjct: 121 DVPRKAKRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQKLGAFL 180 Query: 170 WMQRDVQDPFAPRGQRGVRGVRGGGRGQKDLEDVPYV 206 WMQR++QDPF PRG R RG G ++D+ED+PYV Sbjct: 181 WMQRNLQDPFYPRGPREFRG--GCRAPRRDIEDIPYV 215 >gi|55749442 transcription elongation factor A (SII)-like 4 [Homo sapiens] Length = 215 Score = 184 bits (468), Expect = 4e-47 Identities = 100/217 (46%), Positives = 143/217 (65%), Gaps = 13/217 (5%) Query: 1 MEKLYKENEGKPENERNLESEGKPEDEGSTE-----DEGKSDEEEKPDMEGKTECEGKRE 55 MEKLY ENEG N+ +E+E +P+DE E ++ K + E K + +GKT E + Sbjct: 1 MEKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLK 60 Query: 56 DEGEPGDEGQLED-----EGNQEKQGKSEGEDKPQSEGKPASQAKPESQPRAAEKRPAED 110 D+G+P EG+ ++ EG E +G SE E KP+ EGKP S+ +P S+ RAA KRPAED Sbjct: 61 DKGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAED 120 Query: 111 YVPRKAKRKTDRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRK-KQKMGGFH 169 VPRKAKRKT++G K+ +E + + + S+E+M+RE ++++ Q+E RK KQK+G F Sbjct: 121 DVPRKAKRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQKLGAFL 180 Query: 170 WMQRDVQDPFAPRGQRGVRGVRGGGRGQKDLEDVPYV 206 WMQR++QDPF PRG R RG G ++D+ED+PYV Sbjct: 181 WMQRNLQDPFYPRGPREFRG--GCRAPRRDIEDIPYV 215 >gi|65505873 transcription elongation factor A (SII)-like 4 [Homo sapiens] Length = 215 Score = 184 bits (468), Expect = 4e-47 Identities = 100/217 (46%), Positives = 143/217 (65%), Gaps = 13/217 (5%) Query: 1 MEKLYKENEGKPENERNLESEGKPEDEGSTE-----DEGKSDEEEKPDMEGKTECEGKRE 55 MEKLY ENEG N+ +E+E +P+DE E ++ K + E K + +GKT E + Sbjct: 1 MEKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLK 60 Query: 56 DEGEPGDEGQLED-----EGNQEKQGKSEGEDKPQSEGKPASQAKPESQPRAAEKRPAED 110 D+G+P EG+ ++ EG E +G SE E KP+ EGKP S+ +P S+ RAA KRPAED Sbjct: 61 DKGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAED 120 Query: 111 YVPRKAKRKTDRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRK-KQKMGGFH 169 VPRKAKRKT++G K+ +E + + + S+E+M+RE ++++ Q+E RK KQK+G F Sbjct: 121 DVPRKAKRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQKLGAFL 180 Query: 170 WMQRDVQDPFAPRGQRGVRGVRGGGRGQKDLEDVPYV 206 WMQR++QDPF PRG R RG G ++D+ED+PYV Sbjct: 181 WMQRNLQDPFYPRGPREFRG--GCRAPRRDIEDIPYV 215 >gi|55749451 transcription elongation factor A (SII)-like 4 [Homo sapiens] Length = 215 Score = 184 bits (468), Expect = 4e-47 Identities = 100/217 (46%), Positives = 143/217 (65%), Gaps = 13/217 (5%) Query: 1 MEKLYKENEGKPENERNLESEGKPEDEGSTE-----DEGKSDEEEKPDMEGKTECEGKRE 55 MEKLY ENEG N+ +E+E +P+DE E ++ K + E K + +GKT E + Sbjct: 1 MEKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLK 60 Query: 56 DEGEPGDEGQLED-----EGNQEKQGKSEGEDKPQSEGKPASQAKPESQPRAAEKRPAED 110 D+G+P EG+ ++ EG E +G SE E KP+ EGKP S+ +P S+ RAA KRPAED Sbjct: 61 DKGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAED 120 Query: 111 YVPRKAKRKTDRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRK-KQKMGGFH 169 VPRKAKRKT++G K+ +E + + + S+E+M+RE ++++ Q+E RK KQK+G F Sbjct: 121 DVPRKAKRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQKLGAFL 180 Query: 170 WMQRDVQDPFAPRGQRGVRGVRGGGRGQKDLEDVPYV 206 WMQR++QDPF PRG R RG G ++D+ED+PYV Sbjct: 181 WMQRNLQDPFYPRGPREFRG--GCRAPRRDIEDIPYV 215 >gi|4759128 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 [Homo sapiens] Length = 1099 Score = 65.1 bits (157), Expect = 4e-11 Identities = 50/164 (30%), Positives = 76/164 (46%), Gaps = 17/164 (10%) Query: 6 KENEGKPENERNLESEGK-PEDEGSTEDEGKSDE----EEKPDMEGKTECEGKREDEGEP 60 KEN G E+ ES G+ P +EG T EG+++E E +P+ EG+TE +GK E+ Sbjct: 738 KENPGGQEDVAEAESTGEMPGEEGETAGEGETEEKSGGETQPEGEGETETQGKGEE---- 793 Query: 61 GDEGQLEDEGNQEKQGKSEGEDKPQSEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRK- 119 EDE E +G +EGED+ + + E + + E AE++ K K Sbjct: 794 -----CEDENEAEGKGDNEGEDEGEIHAEDGEMKGNEGETESQE-LSAENHGEAKNDEKG 847 Query: 120 -TDRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKK 162 D G D +E+ +E EE E + +EE +K Sbjct: 848 VEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEEK 891 Score = 54.7 bits (130), Expect = 5e-08 Identities = 38/137 (27%), Positives = 65/137 (47%), Gaps = 9/137 (6%) Query: 7 ENEGKPENERNLESEGKPEDEGSTEDEGKSDE-------EEKPDMEGKTECEGKREDEGE 59 E G+ E E E +PE EG TE +GK +E E K D EG+ E E ED Sbjct: 762 ETAGEGETEEKSGGETQPEGEGETETQGKGEECEDENEAEGKGDNEGEDEGEIHAEDGEM 821 Query: 60 PGDEGQLE-DEGNQEKQGKSEGEDKPQSEGKPASQAKPESQPRAAEKRPAEDYVPRKAKR 118 G+EG+ E E + E G+++ ++K +G + E + E++ E+ + + Sbjct: 822 KGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEE-EEEEQEE 880 Query: 119 KTDRGTDDSPKDSQEDL 135 + + ++ K ++E L Sbjct: 881 EEEEEEEEEEKGNEEPL 897 Score = 45.8 bits (107), Expect = 3e-05 Identities = 43/159 (27%), Positives = 73/159 (45%), Gaps = 26/159 (16%) Query: 3 KLYKENEGKPENER-----NLESEGKPEDEGSTE-----------DEGKSDEEEKPDMEG 46 +L KE E + N+ ++E KPE+E + + K D++E P G Sbjct: 686 RLAKEKEEESLNQGARAQPQAKAESKPEEEEPAKLPAVTVTPAPVPDIKGDQKENP---G 742 Query: 47 KTECEGKREDEGE-PGDEGQLEDEGNQEKQGKSEGEDKPQSEGKPASQAKPESQPRAAEK 105 E + E GE PG+EG+ EG E+ KS GE +P+ EG+ +Q K E ++ Sbjct: 743 GQEDVAEAESTGEMPGEEGETAGEGETEE--KSGGETQPEGEGETETQGKGE---ECEDE 797 Query: 106 RPAEDYVPRKAKRKTD-RGTDDSPKDSQEDLQERHLSSE 143 AE + + + + D K ++ + + + LS+E Sbjct: 798 NEAEGKGDNEGEDEGEIHAEDGEMKGNEGETESQELSAE 836 Score = 45.1 bits (105), Expect = 4e-05 Identities = 31/106 (29%), Positives = 52/106 (49%), Gaps = 10/106 (9%) Query: 7 ENEGKPENERNLESEGKPEDEGSTED---------EGKSDEEEKPDMEGKTECEGKREDE 57 +NEG+ E E + E +EG TE E K+DE+ D G + + E+E Sbjct: 805 DNEGEDEGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEE 864 Query: 58 GEPGDEGQLEDEGNQEKQGKSEGEDKPQSEGKPASQAKPESQPRAA 103 E E + E+E QE++ + E E++ + +P S PE++ + A Sbjct: 865 EEEEQEEE-EEEEEQEEEEEEEEEEEEKGNEEPLSLDWPETRQKQA 909 Score = 40.4 bits (93), Expect = 0.001 Identities = 22/72 (30%), Positives = 40/72 (55%), Gaps = 7/72 (9%) Query: 2 EKLYKENEGKPENERNLESEGKPEDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEGEPG 61 ++L EN G+ +N+ +G D G +E+E + +EE++ E E + E E E Sbjct: 831 QELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQE-------EEEEEEEQEEEEE 883 Query: 62 DEGQLEDEGNQE 73 +E + E++GN+E Sbjct: 884 EEEEEEEKGNEE 895 >gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo sapiens] Length = 1152 Score = 63.9 bits (154), Expect = 9e-11 Identities = 54/208 (25%), Positives = 94/208 (45%), Gaps = 29/208 (13%) Query: 6 KENEGKPENERNLESEGKPED---EGSTEDEGKSDEEEKPDMEGKTECEGK--------R 54 +E EG+ E E E EG+ ED EG E+ EEE+ + EG+ E EG+ Sbjct: 926 EEGEGEGEEE---EGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGE 982 Query: 55 EDEGE-PGDEGQLEDEGNQEKQGKSEGEDKPQSEGKPASQAKPESQPRAAEKRPAEDYVP 113 E+EGE G+E + E+EG +E +G+ EGE + + E + + + E + E E Sbjct: 983 EEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEE 1042 Query: 114 RKAKRKTDRGTDDSPKDSQEDLQE---RHLSSEEMMRECGDVSRAQEELRKKQKMGGFHW 170 + + K G ++ +E+ +E + EE R+ G+ + +++ K G Sbjct: 1043 GEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEEYKKVSKIKGSVKYGKHKT 1102 Query: 171 MQRDVQDPFAPRGQRGVRGVRGGGRGQK 198 Q+ + V +G G+ Q+ Sbjct: 1103 YQK-----------KSVTNTQGNGKEQR 1119 Score = 60.8 bits (146), Expect = 8e-10 Identities = 45/167 (26%), Positives = 77/167 (46%), Gaps = 15/167 (8%) Query: 2 EKLYKENEGKPENERNLESEGKPEDEGSTEDEGKSDEEE-KPDMEGKTECEGKREDEGEP 60 E+ KE E + ERN E E EG E+ G+ +EEE + E + E EGK E EGE Sbjct: 709 EQEQKEREQGHQKERNQEME-----EGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEE 763 Query: 61 GDEGQLEDEGNQEKQGKSEGEDKPQSEGKPASQAKPESQPRAAEKRPA---------EDY 111 + + ++EG ++K+ ++ E+K + EG + E++ R EK E Sbjct: 764 VEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGK 823 Query: 112 VPRKAKRKTDRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEE 158 R+ + + G ++ + +E+ + E E G+ +EE Sbjct: 824 GEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEE 870 Score = 60.8 bits (146), Expect = 8e-10 Identities = 44/142 (30%), Positives = 75/142 (52%), Gaps = 7/142 (4%) Query: 9 EGKPENERNLESEGKPEDEGSTEDEGKSDEEEKPDMEGKTECE-GKREDEGEPGD-EGQL 66 EGK E E E E+EG E+E EEE+ + +G+ E E G+ E+EGE G+ EG+ Sbjct: 821 EGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEE 880 Query: 67 ED-EGNQEKQGKSEGEDKPQSEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGT- 124 E+ EG E++G+ EGE++ + EG+ + + E + E + E+ + + + + G Sbjct: 881 EEGEGEGEEEGEGEGEEE-EGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEG 939 Query: 125 --DDSPKDSQEDLQERHLSSEE 144 +D + +E+ E EE Sbjct: 940 EGEDGEGEGEEEEGEWEGEEEE 961 Score = 58.5 bits (140), Expect = 4e-09 Identities = 51/169 (30%), Positives = 85/169 (50%), Gaps = 15/169 (8%) Query: 7 ENEGKPENERNLESEGKPEDEG-----STEDEGKSDEE-EKPDMEGKTECEGKREDEGEP 60 E EG+ E E E EG+ E+EG E EGK +EE E+ + EG+ E EG E EGE Sbjct: 888 EEEGEGEGEEE-EGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEE-EG--EGEGED 943 Query: 61 GDEGQLEDEG---NQEKQGKSEGEDKPQSEGKPASQAKPESQPRAAEKRPAEDYVPRKAK 117 G+ E+EG +E++G+ EGE++ + EG+ + + E + E E + + Sbjct: 944 GEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGE-EGEGEGEEEEGEGEGEEEEGEEEGEEE 1002 Query: 118 RKTDRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMG 166 + + + ++ +E E + EE E G+ +EE +++K G Sbjct: 1003 GEGEEEGEGEGEEEEEGEVEGEVEGEEGEGE-GEEEEGEEEGEEREKEG 1050 Score = 56.6 bits (135), Expect = 1e-08 Identities = 55/203 (27%), Positives = 96/203 (47%), Gaps = 17/203 (8%) Query: 6 KENEGKPENERNLESEGKPEDEGST---EDEGKSDEEEKPDMEGKTECEGKREDEGEPGD 62 +E EG+ E E E EGK E+EG E+EG+ E E + EG E EG+ E EGE G+ Sbjct: 843 EEEEGEGEEE---EGEGKGEEEGEEGEGEEEGEEGEGEGEEEEG--EGEGEEEGEGE-GE 896 Query: 63 EGQLEDEGNQEKQGKSE---GEDKPQSEGKPASQAKPESQPRAAEKRPAE---DYVPRKA 116 E + E EG +E +G+ E GE K + EG+ + + E + E E + + Sbjct: 897 EEEGEGEGEEEGEGEGEEEEGEGKGEEEGE-EGEGEGEEEEGEGEGEDGEGEGEEEEGEW 955 Query: 117 KRKTDRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRDVQ 176 + + + G + ++ + + +E EE E G+ + E +++ G + + + Sbjct: 956 EGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGE-GEGEEEEGEEEGEEEGEGEEEGEGEGE 1014 Query: 177 DPFAPRGQRGVRGVRGGGRGQKD 199 + + V G G G G+++ Sbjct: 1015 EEEEGEVEGEVEGEEGEGEGEEE 1037 Score = 56.6 bits (135), Expect = 1e-08 Identities = 42/153 (27%), Positives = 80/153 (52%), Gaps = 16/153 (10%) Query: 6 KENEGKPENERNLESEGKPEDEGSTEDEGKSDEEEKPDMEGKTECE-----GKREDEGEP 60 +E EG+ E E E EG+ E EG E EG+ +EEE+ ++EG+ E E G+ E+ E Sbjct: 984 EEGEGEGEEEEG-EEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEE 1042 Query: 61 GDEGQLEDEG-----NQEKQGKSEGEDKPQSEGKPASQAKP-ESQPRAAEKRPAEDYVPR 114 G+E + E EG N+E++ + EG K Q G+ ++ + E + ++ + + Y Sbjct: 1043 GEEREKEGEGEENRRNREEEEEEEG--KYQETGEEENERQDGEEYKKVSKIKGSVKYGKH 1100 Query: 115 KAKRKTDRGTDDSPKDSQEDLQERHLSSEEMMR 147 K +K + ++ + +E + + S+ +++ Sbjct: 1101 KTYQK--KSVTNTQGNGKEQRSKMPVQSKRLLK 1131 Score = 46.2 bits (108), Expect = 2e-05 Identities = 40/161 (24%), Positives = 76/161 (47%), Gaps = 7/161 (4%) Query: 13 ENERNLESEGKPEDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEGEPGDEGQLEDEGNQ 72 E E+ + +G+ E E E E + E+E+ E E K ++G + Q +EG + Sbjct: 673 EREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGE 732 Query: 73 EKQGKSEGED-KPQSEGKPASQAKPESQPRAAE-KRPAEDYVPRKAKR--KTDRGTD--D 126 E+ G+ E E+ + E + + K E + E +R E+ +K +R K ++G + D Sbjct: 733 EEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGD 792 Query: 127 SPKDSQEDLQERHLSSEEMMR-ECGDVSRAQEELRKKQKMG 166 + +E+ + R EE E G+V + E ++++ G Sbjct: 793 QGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEG 833 Score = 43.1 bits (100), Expect = 2e-04 Identities = 48/201 (23%), Positives = 82/201 (40%), Gaps = 14/201 (6%) Query: 7 ENEGKPENERNLESEGKPED----EGSTEDEGKSDEEEKPDMEGKTECEGK-REDEGEPG 61 E G+ E E + E K D E ++G E + EG E G+ E+EG+ Sbjct: 687 ERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDRE 746 Query: 62 DEGQLEDEGNQEKQGKS-EGE-DKPQSEGKPASQA-KPESQPRAAEKRPAEDYVPRKAKR 118 +E + E EG +E +G+ EGE +K + E K +A K E ++ E+ Sbjct: 747 EEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGE 806 Query: 119 KTDRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRDVQDP 178 + + G + + +E ER EE E + +EE +++ G + Sbjct: 807 EKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEG------EGKGEE 860 Query: 179 FAPRGQRGVRGVRGGGRGQKD 199 G+ G G G G+++ Sbjct: 861 EGEEGEGEEEGEEGEGEGEEE 881 Score = 39.3 bits (90), Expect = 0.002 Identities = 50/231 (21%), Positives = 95/231 (41%), Gaps = 37/231 (16%) Query: 7 ENEGKPENERNLESEGKPEDEGSTEDEGKSDEEEKPDMEGKTECEGKRED---------- 56 E + NE N++ G +++ + +D+ E EGK + G+ ED Sbjct: 602 EEQEVEANEENVKVHGGRKEKTEILSDDLTDKAEVS--EGKAKSVGEAEDGPEGRGDGTC 659 Query: 57 -EGEPGDEGQLEDEGNQEKQGKSEGEDKPQSEGKPASQAKPESQPR---AAEKRPAEDYV 112 EG G E ++E + ++ K GE + EG+ K E + R E++ E Sbjct: 660 EEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGH 719 Query: 113 PRKAKRKTDRGTDDSPKDSQEDLQERHLSSE--------------EMMRECGDVSRAQEE 158 ++ ++ + G ++ + +E+ +R E E RE + R +EE Sbjct: 720 QKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEE 779 Query: 159 LRKKQKMGGFHWMQRD-VQDPFAPRGQRGVRG--VRGG----GRGQKDLED 202 K++ G Q + ++ RG+ G V GG G+G+++ E+ Sbjct: 780 RAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEE 830 Score = 29.6 bits (65), Expect = 1.9 Identities = 19/44 (43%), Positives = 25/44 (56%), Gaps = 5/44 (11%) Query: 2 EKLYKENEGKPENERNLESE----GKPEDEGSTEDEGKSDEEEK 41 E+ KE EG+ EN RN E E GK ++ G E+E + EE K Sbjct: 1044 EEREKEGEGE-ENRRNREEEEEEEGKYQETGEEENERQDGEEYK 1086 >gi|21361639 DIPB protein [Homo sapiens] Length = 344 Score = 59.3 bits (142), Expect = 2e-09 Identities = 49/165 (29%), Positives = 75/165 (45%), Gaps = 14/165 (8%) Query: 7 ENEGKPENERNLESEGKPEDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEGEPGDEGQL 66 E GK E E +E E + E E E E + + E + + E + E E + ++E E E ++ Sbjct: 74 EGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEM 133 Query: 67 EDEGNQEKQGKSEGEDKPQSEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRK-TDRGTD 125 EDE QE + + + +++ +SE + ++A+ E P E R AKRK D G D Sbjct: 134 EDE--QESEAEEDNQEEGESEAEGETEAESEFDPE------IEMEAERVAKRKCPDHGLD 185 Query: 126 DSPKDSQEDLQ----ERHLSSEEMMRECGDVSRAQEELRKKQKMG 166 S QED Q + + + A EELR K G Sbjct: 186 LSTY-CQEDRQLICVLCPVIGAHQGHQLSTLDEAFEELRSKDSGG 229 Score = 50.1 bits (118), Expect = 1e-06 Identities = 25/76 (32%), Positives = 44/76 (57%) Query: 6 KENEGKPENERNLESEGKPEDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEGEPGDEGQ 65 +E+E + E+E ESE + E E +++E + D EE+ + E ++E E ++EGE EG+ Sbjct: 97 EESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEEDNQEEGESEAEGE 156 Query: 66 LEDEGNQEKQGKSEGE 81 E E + + + E E Sbjct: 157 TEAESEFDPEIEMEAE 172 Score = 40.0 bits (92), Expect = 0.001 Identities = 23/100 (23%), Positives = 50/100 (50%), Gaps = 2/100 (2%) Query: 36 SDEEEKPDMEGKTECEGKREDEGEPGDEGQLEDEGNQEKQGKS--EGEDKPQSEGKPASQ 93 +D E E + + E +RE E E G+E + E+E E++ ++ E ED+ E + S+ Sbjct: 71 ADGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSE 130 Query: 94 AKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDSQE 133 + E + + + ++ +A+ +T+ ++ P+ E Sbjct: 131 EEMEDEQESEAEEDNQEEGESEAEGETEAESEFDPEIEME 170 Score = 33.1 bits (74), Expect = 0.17 Identities = 16/50 (32%), Positives = 32/50 (64%) Query: 2 EKLYKENEGKPENERNLESEGKPEDEGSTEDEGKSDEEEKPDMEGKTECE 51 E+ +++E + E+E+ E+E ++EG +E EG+++ E + D E + E E Sbjct: 123 EESEEDSEEEMEDEQESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAE 172 Score = 29.6 bits (65), Expect = 1.9 Identities = 19/90 (21%), Positives = 42/90 (46%), Gaps = 1/90 (1%) Query: 70 GNQEKQGKSEGEDKPQSEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKT-DRGTDDSP 128 G+Q ++GE + E + + + E + A E+ +E+ + + +T + D+S Sbjct: 63 GSQAWTPPADGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESD 122 Query: 129 KDSQEDLQERHLSSEEMMRECGDVSRAQEE 158 ++S+ED +E +E E + + E Sbjct: 123 EESEEDSEEEMEDEQESEAEEDNQEEGESE 152 >gi|55956788 nucleolin [Homo sapiens] Length = 710 Score = 57.8 bits (138), Expect = 6e-09 Identities = 38/153 (24%), Positives = 66/153 (43%), Gaps = 5/153 (3%) Query: 11 KPENERNLESEGKPEDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEGEPGDEGQLEDEG 70 K E+ E + EDE EDE + ++E +P EDE + DE +D+ Sbjct: 141 KKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDD 200 Query: 71 NQEKQGKSEGEDKPQSEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKD 130 ++E + E + ++GK A++ P AE ED D DD D Sbjct: 201 DEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAED---EDEEEDDEDEDDDDDEDDEDDD 257 Query: 131 SQEDLQERHLSSEEMMRECGDVSRAQEELRKKQ 163 ++D +E EE ++E + ++E+ K++ Sbjct: 258 DEDDEEEEEEEEEEPVKEA--PGKRKKEMAKQK 288 Score = 39.7 bits (91), Expect = 0.002 Identities = 27/121 (22%), Positives = 55/121 (45%), Gaps = 11/121 (9%) Query: 13 ENERNLESEGKPEDEGSTEDEGKSDEEEKPDMEGK-------TECEGKREDEGEPGDEGQ 65 E+E + + E +D+ ED+ + + E +GK + + EDE E D+ Sbjct: 185 EDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDD-- 242 Query: 66 LEDEGNQEKQGKSEGEDKPQSEGKPASQAKPESQ-PRAAEKRPAEDYVPRKAKRKTDRGT 124 EDE + + + + +D+ E + + +P + P +K A+ +AK++ GT Sbjct: 243 -EDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKKQKVEGT 301 Query: 125 D 125 + Sbjct: 302 E 302 Score = 34.7 bits (78), Expect = 0.059 Identities = 29/146 (19%), Positives = 59/146 (40%), Gaps = 18/146 (12%) Query: 6 KENEGKPENERNLESEGKP--------------EDEGSTEDEGKSDEEEKPDMEGK---- 47 +E+E E+E E E +P ED+ ED+ D++E+ D E + Sbjct: 154 EEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDDEEDDSEEEAMET 213 Query: 48 TECEGKREDEGEPGDEGQLEDEGNQEKQGKSEGEDKPQSEGKPASQAKPESQPRAAEKRP 107 T +GK+ + P + ++ ++E+ + E +D + + + E + E+ Sbjct: 214 TPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPV 273 Query: 108 AEDYVPRKAKRKTDRGTDDSPKDSQE 133 E RK + + ++ K E Sbjct: 274 KEAPGKRKKEMAKQKAAPEAKKQKVE 299 Score = 33.5 bits (75), Expect = 0.13 Identities = 24/84 (28%), Positives = 40/84 (47%), Gaps = 4/84 (4%) Query: 12 PENERNL-ESEGKPEDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEGEPGDEGQLEDEG 70 P +N+ E E + ED+ EDE D+E+ D + + + E + E+E EP E + + Sbjct: 226 PVKAKNVAEDEDEEEDD---EDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKK 282 Query: 71 NQEKQGKSEGEDKPQSEGKPASQA 94 KQ + K + EG + A Sbjct: 283 EMAKQKAAPEAKKQKVEGTEPTTA 306 >gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 [Homo sapiens] Length = 916 Score = 56.2 bits (134), Expect = 2e-08 Identities = 38/104 (36%), Positives = 53/104 (50%), Gaps = 6/104 (5%) Query: 6 KENEGKPENERNLESEGKPEDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEGEPGDEGQ 65 +E E +PE E E K +T E K +E EK + EG+ E E EDEG D+ + Sbjct: 493 EEKEEEPEAEEE-EVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEE--EEDEGAKSDQAE 549 Query: 66 LEDEGNQEKQGKSEGEDKPQSEGKPASQAKPESQPRAAEKRPAE 109 EG EK+G SE E+ Q EG+ ++A+ E EK+ E Sbjct: 550 ---EGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEE 590 Score = 50.8 bits (120), Expect = 8e-07 Identities = 41/134 (30%), Positives = 60/134 (44%), Gaps = 9/134 (6%) Query: 6 KENEGKPENERNLESEGKPEDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEGEPGDEGQ 65 KE EG+ E E E E + EDEG+ D+ + EK EG +E E ++EGE E + Sbjct: 521 KEEEGEKEEEEGQEEE-EEEDEGAKSDQAEEGGSEK---EGSSEKEEGEQEEGETEAEAE 576 Query: 66 LED-EGNQEKQGKSEGEDKPQSEG--KPASQAKPESQPRAAEKRPAED--YVPRKAKRKT 120 E+ E +EK+ + + E+ E A KPE K P E+ P Sbjct: 577 GEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVE 636 Query: 121 DRGTDDSPKDSQED 134 ++G PK E+ Sbjct: 637 EKGKSPVPKSPVEE 650 Score = 36.2 bits (82), Expect = 0.020 Identities = 34/163 (20%), Positives = 67/163 (41%), Gaps = 9/163 (5%) Query: 7 ENEGK-PENERNLESEGK-PEDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEGEPGDEG 64 E +GK P + +E +GK P + E++ KS + P E K++ E + ++ E Sbjct: 649 EEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKE----- 703 Query: 65 QLEDEGNQEKQGKSEGEDKPQSEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGT 124 E+E ++ K E +K + + K + K P E + + K ++ T Sbjct: 704 --EEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKET 761 Query: 125 DDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGG 167 + K Q++ ++ E E G A+ ++ + G Sbjct: 762 KEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNG 804 Score = 35.8 bits (81), Expect = 0.026 Identities = 29/124 (23%), Positives = 53/124 (42%), Gaps = 19/124 (15%) Query: 15 ERNLESEGKPEDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEGEPGD-------EGQLE 67 E+ + EGKP + E+EK EG +E EG D+G G G++E Sbjct: 758 EKETKEEGKPLQQ--------EKEKEKAGGEGGSEEEG--SDKGAKGSRKEDIAVNGEVE 807 Query: 68 DEGNQEKQGKSEGEDKPQSEGKPAS--QAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTD 125 + E++ K +G + + +G + P + + +K + V + ++ T G D Sbjct: 808 GKEEVEQETKEKGSGREEEKGVVTNGLDLSPADEKKGGDKSEEKVVVTKTVEKITSEGGD 867 Query: 126 DSPK 129 + K Sbjct: 868 GATK 871 Score = 28.1 bits (61), Expect = 5.5 Identities = 22/115 (19%), Positives = 49/115 (42%), Gaps = 12/115 (10%) Query: 62 DEGQLEDEGNQ---------EKQGKSEGEDKPQSEGKPASQAKPESQPRAAEKRPAEDYV 112 +E ++EDE ++ E+ S E+K ++ + + + E + AA+K P + Sbjct: 458 EETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATA 517 Query: 113 PRKAKRKTDRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGG 167 P + K + G + + +E+ +E + + E G E + ++ G Sbjct: 518 P---EVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEG 569 >gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 [Homo sapiens] Length = 540 Score = 56.2 bits (134), Expect = 2e-08 Identities = 38/104 (36%), Positives = 53/104 (50%), Gaps = 6/104 (5%) Query: 6 KENEGKPENERNLESEGKPEDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEGEPGDEGQ 65 +E E +PE E E K +T E K +E EK + EG+ E E EDEG D+ + Sbjct: 117 EEKEEEPEAEEE-EVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEE--EEDEGAKSDQAE 173 Query: 66 LEDEGNQEKQGKSEGEDKPQSEGKPASQAKPESQPRAAEKRPAE 109 EG EK+G SE E+ Q EG+ ++A+ E EK+ E Sbjct: 174 ---EGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEE 214 Score = 50.8 bits (120), Expect = 8e-07 Identities = 41/134 (30%), Positives = 60/134 (44%), Gaps = 9/134 (6%) Query: 6 KENEGKPENERNLESEGKPEDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEGEPGDEGQ 65 KE EG+ E E E E + EDEG+ D+ + EK EG +E E ++EGE E + Sbjct: 145 KEEEGEKEEEEGQEEE-EEEDEGAKSDQAEEGGSEK---EGSSEKEEGEQEEGETEAEAE 200 Query: 66 LED-EGNQEKQGKSEGEDKPQSEG--KPASQAKPESQPRAAEKRPAED--YVPRKAKRKT 120 E+ E +EK+ + + E+ E A KPE K P E+ P Sbjct: 201 GEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVE 260 Query: 121 DRGTDDSPKDSQED 134 ++G PK E+ Sbjct: 261 EKGKSPVPKSPVEE 274 Score = 36.2 bits (82), Expect = 0.020 Identities = 34/163 (20%), Positives = 67/163 (41%), Gaps = 9/163 (5%) Query: 7 ENEGK-PENERNLESEGK-PEDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEGEPGDEG 64 E +GK P + +E +GK P + E++ KS + P E K++ E + ++ E Sbjct: 273 EEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKE----- 327 Query: 65 QLEDEGNQEKQGKSEGEDKPQSEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGT 124 E+E ++ K E +K + + K + K P E + + K ++ T Sbjct: 328 --EEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKET 385 Query: 125 DDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGG 167 + K Q++ ++ E E G A+ ++ + G Sbjct: 386 KEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNG 428 Score = 35.8 bits (81), Expect = 0.026 Identities = 29/124 (23%), Positives = 53/124 (42%), Gaps = 19/124 (15%) Query: 15 ERNLESEGKPEDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEGEPGD-------EGQLE 67 E+ + EGKP + E+EK EG +E EG D+G G G++E Sbjct: 382 EKETKEEGKPLQQ--------EKEKEKAGGEGGSEEEG--SDKGAKGSRKEDIAVNGEVE 431 Query: 68 DEGNQEKQGKSEGEDKPQSEGKPAS--QAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTD 125 + E++ K +G + + +G + P + + +K + V + ++ T G D Sbjct: 432 GKEEVEQETKEKGSGREEEKGVVTNGLDLSPADEKKGGDKSEEKVVVTKTVEKITSEGGD 491 Query: 126 DSPK 129 + K Sbjct: 492 GATK 495 Score = 28.1 bits (61), Expect = 5.5 Identities = 22/115 (19%), Positives = 49/115 (42%), Gaps = 12/115 (10%) Query: 62 DEGQLEDEGNQ---------EKQGKSEGEDKPQSEGKPASQAKPESQPRAAEKRPAEDYV 112 +E ++EDE ++ E+ S E+K ++ + + + E + AA+K P + Sbjct: 82 EETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATA 141 Query: 113 PRKAKRKTDRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGG 167 P + K + G + + +E+ +E + + E G E + ++ G Sbjct: 142 P---EVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEG 193 >gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] Length = 2400 Score = 56.2 bits (134), Expect = 2e-08 Identities = 51/169 (30%), Positives = 80/169 (47%), Gaps = 20/169 (11%) Query: 7 ENEGKPENE--RNLESEGK--PEDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEGEPGD 62 E E +PE E LE+EG+ PE EG+ E + EE + EG+T+ E + + E + Sbjct: 1912 EKEAQPETESVEALETEGEDEPESEGA---EAQEAEEAAQEAEGQTQPESEVIESQEAEE 1968 Query: 63 EGQLEDEGNQEKQ-----GKSEGEDKPQSEGKPASQAKPESQPRAAEKRPAEDYVPRKAK 117 E Q E E + + ++EGE +P+SE A +A+ E Q E +P D V + K Sbjct: 1969 EAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPK 2028 Query: 118 ------RKTDRGTDDSPKDSQ--EDLQERHLSSEEMMRECGDVSRAQEE 158 ++ + T + D+Q D E + EE G+V A+ E Sbjct: 2029 SEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGE 2077 Score = 55.5 bits (132), Expect = 3e-08 Identities = 46/145 (31%), Positives = 68/145 (46%), Gaps = 16/145 (11%) Query: 13 ENERNLESEG--KPEDEGSTEDEGKSDEEEKPDMEGKTECEG----KREDEGEPGDEG-- 64 E E ESEG PE EG + E + E + + E + E EG + E+E +P EG Sbjct: 2122 EGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVE 2181 Query: 65 --QLEDEGNQEKQG----KSEGEDKPQSEGKPASQAKPESQ--PRAAEKRPAEDYVPRKA 116 + E E E +G ++EGE +P+ EG A +A+ E+Q P E AE ++ Sbjct: 2182 APEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGVETPEAEGEAQPES 2241 Query: 117 KRKTDRGTDDSPKDSQEDLQERHLS 141 + +T SP+ S D Q S Sbjct: 2242 EGETQGEKKGSPQVSLGDGQSEEAS 2266 Score = 55.5 bits (132), Expect = 3e-08 Identities = 40/136 (29%), Positives = 68/136 (50%), Gaps = 16/136 (11%) Query: 7 ENEGKPENE----RNLESEGKPEDEGSTEDEGKSDEEEKPDMEG--KTECEGKREDEGEP 60 E E +PE+E ++ E E +PE EG E ++EE +P++EG E EG+ + E E Sbjct: 2138 EGEAQPESEGVEAQDAEGEAQPESEGIEAQE--AEEEAQPELEGVEAPEAEGEAQPESEG 2195 Query: 61 GDEGQLEDEGNQEKQG----KSEGEDKPQSEGKPASQAKPESQPRAAEKRPAEDYVPRKA 116 + + E E E +G ++E E +P+ EG +A+ E+QP + + E +K Sbjct: 2196 IEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGVETPEAEGEAQPESEGETQGE----KKG 2251 Query: 117 KRKTDRGTDDSPKDSQ 132 + G S + S+ Sbjct: 2252 SPQVSLGDGQSEEASE 2267 Score = 55.1 bits (131), Expect = 4e-08 Identities = 43/171 (25%), Positives = 73/171 (42%), Gaps = 15/171 (8%) Query: 19 ESEGKPEDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEGEPGDEGQLEDEGNQEKQGKS 78 E E +PE EG E + D +E EG+ + E ED P EG+ + E + ++ Sbjct: 1841 EGEAQPESEGVEAPEAEGDAQEA---EGEAQPES--EDVEAPEAEGEAQPESEDVETPEA 1895 Query: 79 EGEDKPQSEGKPASQAKPESQPRA---------AEKRPAEDYVPRKAKRKTDRGTDDSPK 129 E E +P+SEG A +A+ E+QP E P + + + + + + Sbjct: 1896 EWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQ 1955 Query: 130 DSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRDVQDPFA 180 E ++ + + EE E DV + E+ ++ G DV+ P A Sbjct: 1956 PESEVIESQE-AEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEA 2005 Score = 55.1 bits (131), Expect = 4e-08 Identities = 45/168 (26%), Positives = 80/168 (47%), Gaps = 27/168 (16%) Query: 1 MEKLYKENEGKPENE---------RNLESEGKPEDEGSTEDEGKSDEEEKPDMEG----- 46 +E L E E +PE+E E+EG+ + E + +++EE +P+ E Sbjct: 1922 VEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALE 1981 Query: 47 ----KTECEGKREDEGE----PGDEGQLEDEGNQEKQGKSEG-EDKPQSEGKPASQAKPE 97 E EG+ + E E P EG+++ E +E Q +S+G E +P+SEG+ A + + E Sbjct: 1982 VEVETQEAEGEAQPESEDVEAPEAEGEMQ-EAEEEAQPESDGVEAQPKSEGEEAQEVEGE 2040 Query: 98 SQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDSQEDLQERHLSSEEM 145 +Q + +P D V + + ++ + QE E H SE++ Sbjct: 2041 TQKTEGDAQPESDGVEAP---EAEEEAQEAEGEVQEAEGEAHPESEDV 2085 Score = 54.7 bits (130), Expect = 5e-08 Identities = 46/166 (27%), Positives = 75/166 (45%), Gaps = 18/166 (10%) Query: 7 ENEGKPENERNLESEGKPEDEGSTEDEGKSDEEEKPDMEGKTECEGKR----EDEGEPGD 62 E EG+ + +E+ PE EG + E + E + + E + E EG E E +P Sbjct: 2105 EAEGEAQKAEGIEA---PETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPES 2161 Query: 63 EG----QLEDEGNQEKQG----KSEGEDKPQSEGKPASQAKPESQP--RAAEKRPAEDYV 112 EG + E+E E +G ++EGE +P+SEG A +A+ E+QP E AE+ Sbjct: 2162 EGIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEA 2221 Query: 113 -PRKAKRKTDRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQE 157 P +T ++ +S+ + Q S ++ G A E Sbjct: 2222 QPEPEGVETPEAEGEAQPESEGETQGEKKGSPQVSLGDGQSEEASE 2267 Score = 52.0 bits (123), Expect = 4e-07 Identities = 44/204 (21%), Positives = 88/204 (43%), Gaps = 11/204 (5%) Query: 7 ENEGKPENERNLESEGKPEDEGSTEDEGKSDEEE---KPDMEGKTECEGKREDEGEPGDE 63 E E +PE++ +E++ K E E + E EG++ + E +P+ +G E + E + G+ Sbjct: 2013 EEEAQPESD-GVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEV 2071 Query: 64 GQLEDEGNQEKQG----KSEGEDKPQSEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRK 119 + E E + E + ++EGE +P+SEG A +A+ E+Q + P + + Sbjct: 2072 QEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEG 2131 Query: 120 TDRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRDVQDPF 179 + + + + E + E E + + E + ++ G + + + Sbjct: 2132 IEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAPEAEGE--- 2188 Query: 180 APRGQRGVRGVRGGGRGQKDLEDV 203 A G+ G Q +LE V Sbjct: 2189 AQPESEGIEAPEAEGEAQPELEGV 2212 Score = 45.8 bits (107), Expect = 3e-05 Identities = 43/137 (31%), Positives = 58/137 (42%), Gaps = 15/137 (10%) Query: 7 ENEGKPENER----NLESEGKPEDEGSTEDEGKSDEEEKPDMEG----KTECEGKREDEG 58 E E +PE E E E +PE EG E + E +P++EG + E E + E EG Sbjct: 2170 EEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEG--EAQPELEGVEAPEAEEEAQPEPEG 2227 Query: 59 --EPGDEGQLEDEGNQEKQGKSEGEDKPQ-SEGKPASQAKPESQPRAAEKRPAEDYVPRK 115 P EG+ + E E QG+ +G PQ S G S+ ES E RP P Sbjct: 2228 VETPEAEGEAQPESEGETQGEKKG--SPQVSLGDGQSEEASESSSPVPEDRPTPPPSPGG 2285 Query: 116 AKRKTDRGTDDSPKDSQ 132 G+ P S+ Sbjct: 2286 DTPHQRPGSQTGPSSSR 2302 Score = 45.4 bits (106), Expect = 3e-05 Identities = 33/116 (28%), Positives = 53/116 (45%), Gaps = 11/116 (9%) Query: 2 EKLYKENEGKPENERNLESEGKPEDEGSTEDEGKSDEEE--------KPDMEGKTECEGK 53 + + +E EGK N S G E E EG S+ E + +++G+ G Sbjct: 1766 DAMAQEREGKTHNSET--SAGSELGEAEQEGEGISERGETGGQGSGHEDNLQGEAAAGGD 1823 Query: 54 REDEGEPGDEGQLEDEGNQEKQGKSEGEDKPQSEGKPASQAKPESQPRAAEKRPAE 109 ++ G EG E E Q +SEG + P++EG A +A+ E+QP + + E Sbjct: 1824 QDPGQSDGAEGIEAPEAEGEAQPESEGVEAPEAEG-DAQEAEGEAQPESEDVEAPE 1878 Score = 41.2 bits (95), Expect = 6e-04 Identities = 58/223 (26%), Positives = 89/223 (39%), Gaps = 37/223 (16%) Query: 7 ENEGKPENER----NLESEGKPEDEG----STEDEGKSDEE--EKPDMEGKTECEGKRED 56 E E +PE+E E E +PE EG E+E + + E E P+ EG+ + E + E Sbjct: 2186 EGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGVETPEAEGEAQPESEGET 2245 Query: 57 EGEPGDEGQLE-DEGNQEKQGKSEG---EDK---PQSEG------KPASQAKPESQPRAA 103 +GE Q+ +G E+ +S ED+ P S G +P SQ P S ++ Sbjct: 2246 QGEKKGSPQVSLGDGQSEEASESSSPVPEDRPTPPPSPGGDTPHQRPGSQTGPSSSRASS 2305 Query: 104 -----EKRPAEDYVPRKAKRKTDRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEE 158 +K D+V R D + +P ++ + SS E SR E+ Sbjct: 2306 WGNCWQKDSENDHVLGDT-RSPDAKSTGTPHAERKATRMYPESSTSEQEEAPLGSRTPEQ 2364 Query: 159 LRKKQKMGGFHWMQRDVQDPFAPRGQRGVRGVRGGGRGQKDLE 201 + G+ + AP G R G GQ DL+ Sbjct: 2365 GASE----GYDLQEDQALGSLAPTEAVG----RADGFGQDDLD 2399 Score = 39.3 bits (90), Expect = 0.002 Identities = 38/159 (23%), Positives = 67/159 (42%), Gaps = 15/159 (9%) Query: 1 MEKLYKENEGKPENERNLESEGKPEDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEGEP 60 +E+ + EG+ E ++ E +EG E+ + +E ++ + EG+ E E + E+ E Sbjct: 1303 LEETKEGTEGEGLQEEAVQLEETKTEEGLQEEGVQLEETKETEGEGQQEEEAQLEEIEET 1362 Query: 61 GDEG------QLED-----EGNQEKQGKSEG--EDKPQSEGKPASQAKPESQPRAAEKRP 107 G EG QLE+ EG + + EG E+ EG Q E+ + Sbjct: 1363 GGEGLQEEGVQLEEVKEGPEGGLQGEALEEGLKEEGLPEEGSVHGQELSEASSPDGKGSQ 1422 Query: 108 AEDYVPRKAKRKTDRGTDDSPKDSQEDLQE--RHLSSEE 144 +D V + + + P + E+ E HLS + Sbjct: 1423 EDDPVQEEEAGRASASAEPCPAEGTEEPTEPPSHLSETD 1461 Score = 30.4 bits (67), Expect = 1.1 Identities = 26/102 (25%), Positives = 40/102 (39%), Gaps = 6/102 (5%) Query: 52 GKREDEGEPGDEGQLEDEGNQEKQGKSEGEDKPQSEGKP------ASQAKPESQPRAAEK 105 G R E +PGD+ LE G + G+ E P + +P +S P+S + Sbjct: 986 GLRGPEVDPGDDHSLEGLGEPAQAGQQSLEGDPGQDPEPEGALLGSSDTGPQSGEGVPQG 1045 Query: 106 RPAEDYVPRKAKRKTDRGTDDSPKDSQEDLQERHLSSEEMMR 147 E A+ DR + S L R +S ++MR Sbjct: 1046 AAPEGVSEAPAEAGADREAPAGCRVSLRALPGRVSASTQIMR 1087 Score = 29.6 bits (65), Expect = 1.9 Identities = 34/129 (26%), Positives = 50/129 (38%), Gaps = 16/129 (12%) Query: 15 ERNLESEGKPEDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEGEPGDEGQLEDEGNQEK 74 E L+ EG PE EGS + S E PD GK E +P E + + Sbjct: 1391 EEGLKEEGLPE-EGSVHGQELS-EASSPD--------GKGSQEDDPVQEEEAGRASASAE 1440 Query: 75 QGKSEGEDKPQSEGKPASQAKPESQPRAAEKRPAEDYVP--RKAKRKTDRGTDDSPKDSQ 132 +EG ++P +P S E+ P A+E++ P K T G + + Sbjct: 1441 PCPAEGTEEPT---EPPSHLS-ETDPSASERQSGSQLEPGLEKPPGATMMGQEHTQAQPT 1496 Query: 133 EDLQERHLS 141 + ER S Sbjct: 1497 QGAAERSSS 1505 Score = 28.1 bits (61), Expect = 5.5 Identities = 24/84 (28%), Positives = 41/84 (48%), Gaps = 2/84 (2%) Query: 7 ENEGKPENERNLESEGKPEDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEGEPGDEGQL 66 E+E + ++E S + +T E EE K EG+ E + E +EG L Sbjct: 1273 EDEAERDSEEQRASSNLEQLAENTVQEEVQLEETKEGTEGEGLQEEAVQLEETKTEEG-L 1331 Query: 67 EDEGNQ-EKQGKSEGEDKPQSEGK 89 ++EG Q E+ ++EGE + + E + Sbjct: 1332 QEEGVQLEETKETEGEGQQEEEAQ 1355 >gi|13540523 nucleosomal binding protein 1 [Homo sapiens] Length = 282 Score = 55.8 bits (133), Expect = 2e-08 Identities = 42/156 (26%), Positives = 72/156 (46%), Gaps = 13/156 (8%) Query: 2 EKLYKENEGKPENERNLESEGKPEDEGSTEDEG---KSDEEEKPDMEGKTECEG--KRED 56 EK ++ E +N E + K ++E E++G K D++EK + +GK + G K ED Sbjct: 110 EKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGED 169 Query: 57 EGEPGDEGQLEDEGNQEKQGKSEGEDKPQSE-------GKPASQAKPESQPR-AAEKRPA 108 E D + ED + GK +GED+ + E GK K + + + + Sbjct: 170 AKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVK 229 Query: 109 EDYVPRKAKRKTDRGTDDSPKDSQEDLQERHLSSEE 144 ED R+ ++ + G ++ +EDL+E EE Sbjct: 230 EDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEE 265 Score = 51.6 bits (122), Expect = 5e-07 Identities = 39/161 (24%), Positives = 73/161 (45%), Gaps = 10/161 (6%) Query: 9 EGKPENERNLESEGKPEDEGSTEDEGKSDEEEKPDMEGKTECEGK--REDEGEPGDEGQL 66 E K EN + +G + E + +E++K D E + E +G+ +ED+ E G+E Sbjct: 99 EVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEE--- 155 Query: 67 EDEGNQEKQGKSEGED-KPQSEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTD 125 +G ++K G +GED K + +GK K + + ++ RK D Sbjct: 156 --DGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENED 213 Query: 126 DSPKDSQEDLQERHLSSEEMMRECG--DVSRAQEELRKKQK 164 K +++ ++ + +E RE G D +EE K+++ Sbjct: 214 GKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKE 254 Score = 45.8 bits (107), Expect = 3e-05 Identities = 37/131 (28%), Positives = 59/131 (45%), Gaps = 13/131 (9%) Query: 7 ENEGKPENERNLESE-GKPEDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEGEPGDEGQ 65 E +GK + N + E K +++G ++GK + E D + K E E + ED E GD + Sbjct: 154 EEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGE---DGKEKGEDEKEEEDRKETGDGKE 210 Query: 66 LEDEGNQEKQGKSEGED-------KPQSEGKPASQAKPESQPRAAEKRPAEDYVPRKAKR 118 ED +EK K EG+D K + +GK E + E E+ + + Sbjct: 211 NED--GKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEI 268 Query: 119 KTDRGTDDSPK 129 K D G + P+ Sbjct: 269 KEDDGKKEEPQ 279 Score = 44.7 bits (104), Expect = 6e-05 Identities = 31/111 (27%), Positives = 53/111 (47%), Gaps = 19/111 (17%) Query: 6 KENEGKPENERNLESEGKPED-EGSTEDEGKSDEEEKPDMEGKTECEGKREDEG-EPGD- 62 K K E+ + E K ED +G+ ED + E+EK + + K +GK ++G E GD Sbjct: 161 KNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDK 220 Query: 63 ----------------EGQLEDEGNQEKQGKSEGEDKPQSEGKPASQAKPE 97 +G+ ++ GN+E+ GK + + K + EGK + K + Sbjct: 221 KEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKED 271 Score = 43.1 bits (100), Expect = 2e-04 Identities = 22/84 (26%), Positives = 45/84 (53%), Gaps = 1/84 (1%) Query: 6 KENEGKPENERNLESEGKPEDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEGEPGDEGQ 65 K + K E +R +GK ++G + + K ++ K + K +GK ++ G + G+ Sbjct: 192 KGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGK 251 Query: 66 LEDEGNQEKQGKSEGEDKPQSEGK 89 +++ +E++GK E E K + +GK Sbjct: 252 EKEDLKEEEEGKEEDEIK-EDDGK 274 Score = 40.4 bits (93), Expect = 0.001 Identities = 46/175 (26%), Positives = 77/175 (44%), Gaps = 31/175 (17%) Query: 1 MEKLYKEN----EGK----PENERNLESEGKPEDEGSTEDEGKSDEEEKPDMEGKTECEG 52 +E+ Y EN E K P +E+ + + E +TE G +++E E K E E Sbjct: 72 VEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGG--EKKEAVAAEVKNEEED 129 Query: 53 KREDEGEPGDEGQLEDEGNQEKQGKSEGEDKPQSEGKPASQAKPESQPRAAEKRPAEDYV 112 ++EDE E Q E++G + GK + ++K + +GK + + A EK + Sbjct: 130 QKEDE-----EDQNEEKG---EAGKEDKDEKGEEDGKEDKNGNEKGED-AKEKEDGK--- 177 Query: 113 PRKAKRKTDRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGG 167 K + +G + K+ ED +E EE +E GD ++ K K G Sbjct: 178 ----KGEDGKGNGEDGKEKGEDEKE-----EEDRKETGDGKENEDGKEKGDKKEG 223 >gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] Length = 245 Score = 55.1 bits (131), Expect = 4e-08 Identities = 42/155 (27%), Positives = 78/155 (50%), Gaps = 14/155 (9%) Query: 13 ENERNLES--EGKPEDEGSTEDEGKSDEEEKPDMEGKTECE-GKREDEGEPGDEGQLEDE 69 E ER +E+ EGK E E + E + E+ K + E + + E GK+E +GE E + + Sbjct: 40 EREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKK 99 Query: 70 GNQEKQGKSEGEDKPQSEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPK 129 +EK+ K EGE+K + + K E + R + ++ ++ +++ +R + K Sbjct: 100 RRREKENK-EGEEKEK-------RKKKEKKERGRTSKEGKERERKEERKREERKERERKK 151 Query: 130 DSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQK 164 + +E +ER E RE V +EE ++K++ Sbjct: 152 EEREKERER---KERKKRERKQVGEKEEERKEKER 183 Score = 50.4 bits (119), Expect = 1e-06 Identities = 34/160 (21%), Positives = 78/160 (48%), Gaps = 3/160 (1%) Query: 6 KENEGKPENERNLESEGKPEDEGSTEDE-GKSDEEEKPDMEGKTECEGKREDEGEPGDEG 64 KE E + + ER + K E E + E GK +++ + E + + +RE E + G+E Sbjct: 53 KERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEK 112 Query: 65 QLEDEGNQEKQGKSEGEDKPQSEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGT 124 + + ++++G++ E K + + + + + + R E+R E RK ++K +R Sbjct: 113 EKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKER--ERKERKKRERKQ 170 Query: 125 DDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQK 164 ++ +++ + + E R+ R ++E R+++K Sbjct: 171 VGEKEEERKEKERKERKKRERNRKERKKERERKERRERKK 210 Score = 47.0 bits (110), Expect = 1e-05 Identities = 39/175 (22%), Positives = 80/175 (45%), Gaps = 9/175 (5%) Query: 2 EKLYKENEGKPENERNLESEGKPEDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEGEPG 61 EK +E E + + ER GK E +G + E + ++ + + E K E ++ + E Sbjct: 67 EKRKREREKERKRER-----GKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKK 121 Query: 62 DEGQLEDEGNQEKQGKSEGEDKPQSEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTD 121 + G+ EG +E++ K E + + + E + + + + + R K+ V K + + + Sbjct: 122 ERGRTSKEG-KERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKE 180 Query: 122 RGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKK--QKMGGFHWMQRD 174 + + K + + +ER E R R ++E RKK QK +W +++ Sbjct: 181 KERKER-KKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKE 234 Score = 42.4 bits (98), Expect = 3e-04 Identities = 32/151 (21%), Positives = 63/151 (41%), Gaps = 13/151 (8%) Query: 6 KENEGKPENERNLESEGKPEDE------------GSTEDEGKSDEEEKPDMEGKTECEGK 53 ++ E + +R E E K +E G T EGK + E K + + + E + Sbjct: 90 RKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGK-ERERKEERKREERKERE 148 Query: 54 REDEGEPGDEGQLEDEGNQEKQGKSEGEDKPQSEGKPASQAKPESQPRAAEKRPAEDYVP 113 R+ E + + E + + KQ + E++ + E K + + + R E+ E Sbjct: 149 RKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRER 208 Query: 114 RKAKRKTDRGTDDSPKDSQEDLQERHLSSEE 144 +K ++K + + KD Q + +E+ E Sbjct: 209 KKERKKKEERKKERQKDRQTNWREKERGKRE 239 Score = 32.7 bits (73), Expect = 0.22 Identities = 22/88 (25%), Positives = 42/88 (47%), Gaps = 2/88 (2%) Query: 2 EKLYKENEGKPENERNLESEGKPEDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEGEPG 61 E+ KE E K +R + G+ E+E ++ + + E+ E K E E R++ E Sbjct: 152 EEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERE--RKERRERK 209 Query: 62 DEGQLEDEGNQEKQGKSEGEDKPQSEGK 89 E + ++E +E+Q + + + GK Sbjct: 210 KERKKKEERKKERQKDRQTNWREKERGK 237 >gi|55749466 transcription elongation factor A (SII)-like 8 [Homo sapiens] Length = 117 Score = 53.9 bits (128), Expect = 9e-08 Identities = 33/98 (33%), Positives = 51/98 (52%), Gaps = 3/98 (3%) Query: 79 EGEDKPQSEGKPASQAKPESQPRAAE--KRPAEDYVPRKAKRKTDRGTDDSPKDSQEDLQ 136 E E KPQ+ K E P+ AE +P+E+ V ++A+ G + + +ED Sbjct: 7 ENEGKPQNMPKAEEDRPLEDVPQEAEGNPQPSEEGVSQEAEGNPRGGPNQPGQGFKEDTP 66 Query: 137 ERHLSSEEMMRECGDVSRAQEELRK-KQKMGGFHWMQR 173 RHL EEM+R ++ R +EE+R+ + K HW QR Sbjct: 67 VRHLDPEEMIRGVDELERLREEIRRVRNKFVMMHWKQR 104 Score = 33.9 bits (76), Expect = 0.10 Identities = 23/65 (35%), Positives = 33/65 (50%), Gaps = 6/65 (9%) Query: 1 MEKLYKENEGKPENERNLESEGKPEDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEGEP 60 M+K +ENEGKP+N E E +P ++ E EG +P EG ++ E + G P Sbjct: 1 MQKSCEENEGKPQNMPKAE-EDRPLEDVPQEAEG----NPQPSEEGVSQ-EAEGNPRGGP 54 Query: 61 GDEGQ 65 GQ Sbjct: 55 NQPGQ 59 >gi|23503247 transcription elongation factor A (SII)-like 8 [Homo sapiens] Length = 117 Score = 53.9 bits (128), Expect = 9e-08 Identities = 33/98 (33%), Positives = 51/98 (52%), Gaps = 3/98 (3%) Query: 79 EGEDKPQSEGKPASQAKPESQPRAAE--KRPAEDYVPRKAKRKTDRGTDDSPKDSQEDLQ 136 E E KPQ+ K E P+ AE +P+E+ V ++A+ G + + +ED Sbjct: 7 ENEGKPQNMPKAEEDRPLEDVPQEAEGNPQPSEEGVSQEAEGNPRGGPNQPGQGFKEDTP 66 Query: 137 ERHLSSEEMMRECGDVSRAQEELRK-KQKMGGFHWMQR 173 RHL EEM+R ++ R +EE+R+ + K HW QR Sbjct: 67 VRHLDPEEMIRGVDELERLREEIRRVRNKFVMMHWKQR 104 Score = 33.9 bits (76), Expect = 0.10 Identities = 23/65 (35%), Positives = 33/65 (50%), Gaps = 6/65 (9%) Query: 1 MEKLYKENEGKPENERNLESEGKPEDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEGEP 60 M+K +ENEGKP+N E E +P ++ E EG +P EG ++ E + G P Sbjct: 1 MQKSCEENEGKPQNMPKAE-EDRPLEDVPQEAEG----NPQPSEEGVSQ-EAEGNPRGGP 54 Query: 61 GDEGQ 65 GQ Sbjct: 55 NQPGQ 59 >gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo sapiens] Length = 600 Score = 52.8 bits (125), Expect = 2e-07 Identities = 43/171 (25%), Positives = 71/171 (41%), Gaps = 18/171 (10%) Query: 6 KENEGKPENERNLESEGKPED-------------EGSTEDEGKSDEEEKPDMEGKTECEG 52 K + + E ER E E K ED E TE E K + + D + KTE E Sbjct: 183 KNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTERER 242 Query: 53 KREDEGEPGDEGQLEDEGNQEKQGKSEGEDKPQSEGKPASQAKPESQPRAAEKRPAEDYV 112 +++ E E E + E + +E++ + D+ + + + Q + Q R R E Sbjct: 243 EKQAERERASERETERDKERERE-RDRDRDRDRRQKERERQTDRKRQRRTERDRETE--- 298 Query: 113 PRKAKRKTDRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQ 163 RK +R+ +R + +E +ER E D + +E RK+Q Sbjct: 299 -RKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQ 348 Score = 49.3 bits (116), Expect = 2e-06 Identities = 37/168 (22%), Positives = 80/168 (47%), Gaps = 12/168 (7%) Query: 6 KENEGKPENERNLESEGKPEDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEGEPGDEGQ 65 ++ +G+ E ER ++E + E + E + +++ + + E + + +RE E + E + Sbjct: 141 RQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENK 200 Query: 66 LED-------EGNQEKQGKSEGEDKPQSEGKPASQAKP--ESQPRAAEKRPAEDYVPRKA 116 ED E +E++ ++E E K Q++ + Q K E + +A +R +E R Sbjct: 201 TEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDK 260 Query: 117 KRKTDRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQK 164 +R+ +R D +D +ER ++ + + R E R++Q+ Sbjct: 261 ERERER---DRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQR 305 Score = 48.1 bits (113), Expect = 5e-06 Identities = 37/163 (22%), Positives = 77/163 (47%), Gaps = 5/163 (3%) Query: 6 KENEGKPENERNLESEGKPEDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEGEPGDEGQ 65 +E + + +R+ E + E E + + + D + + + + E E + E EGE G + Q Sbjct: 83 REKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQ 142 Query: 66 LEDEGNQEKQGKSEGEDKPQSEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTD 125 + + +E+Q +E E + Q++ + Q + Q ++ ++ R+ +R+ + T+ Sbjct: 143 TDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTE 202 Query: 126 DSPKD-SQEDLQERHLSSE-EMMRECG---DVSRAQEELRKKQ 163 D + +E +ER +E E R+ D R E R+KQ Sbjct: 203 DRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQ 245 Score = 47.4 bits (111), Expect = 9e-06 Identities = 38/167 (22%), Positives = 74/167 (44%), Gaps = 6/167 (3%) Query: 3 KLYKENEGKPENERNLESEGKPEDEGSTE-----DEGKSDEEEKPDMEGKTECEGKREDE 57 K +E E + E ER E E + + E E D + +E + + K + +R+ E Sbjct: 237 KTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRE 296 Query: 58 GEPGDEGQLEDEGNQEKQGKSEGEDKPQSEGKPASQAKPESQPRAAEKRPAEDYVPRKAK 117 E E Q E E +E+ K E E + + E + + + + + KR + + R+ Sbjct: 297 TERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERN 356 Query: 118 RKTDR-GTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQ 163 R+T R G + ++ + + + S+ E D R +++ R++Q Sbjct: 357 RQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQ 403 Score = 46.2 bits (108), Expect = 2e-05 Identities = 44/169 (26%), Positives = 73/169 (43%), Gaps = 15/169 (8%) Query: 6 KENEGKPENERNLESEGKPEDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEGEPGDEGQ 65 +E E + ER E+E + E + +G+ + E + D E + E + RE + + Q Sbjct: 117 REKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQ 176 Query: 66 LEDEGNQEKQGKSEGEDKPQSEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTD 125 E E + +Q + E E + + E K + + R E+ E + KR+TDR D Sbjct: 177 KEREREKNRQERRERERQREKENKTEDRHSERGRERERER---ETETETERKRQTDRERD 233 Query: 126 DSPKDSQEDLQ--ERHLSSE-------EMMRECG---DVSRAQEELRKK 162 K +E + ER +SE E RE D R Q+E ++ Sbjct: 234 RQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQ 282 Score = 45.1 bits (105), Expect = 4e-05 Identities = 33/152 (21%), Positives = 72/152 (47%), Gaps = 1/152 (0%) Query: 13 ENERNLESEGKPEDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEGEPGDEGQLEDEGNQ 72 E ER + + + E E E K + + + + E + + +RE E E E Q E E ++ Sbjct: 278 ERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDR 337 Query: 73 EKQGKSEGEDKPQSEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDSQ 132 EK+ + + + + + + + Q E + +A +R E R++ R+ + D +D Q Sbjct: 338 EKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQ 397 Query: 133 EDLQERHLSSEEMMRECGDVSRAQEELRKKQK 164 ++ + + + RE + R +E+ R+ ++ Sbjct: 398 KERERQTEKDRDGQRET-EKQREREKDRESER 428 Score = 44.3 bits (103), Expect = 7e-05 Identities = 30/140 (21%), Positives = 65/140 (46%), Gaps = 7/140 (5%) Query: 6 KENEGKPENERNLESEGKPEDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEGEPGDEGQ 65 +E E + E R E E + E E + E + D E++ + + K + E RE + G EG+ Sbjct: 305 RERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGR 364 Query: 66 LEDEGNQEKQGKSEGEDKPQSEGKPASQAKPESQPRAAE-------KRPAEDYVPRKAKR 118 + E +E++ + + + + E + + + + R + +R E R+ R Sbjct: 365 RQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDR 424 Query: 119 KTDRGTDDSPKDSQEDLQER 138 +++RG + + ++ +ER Sbjct: 425 ESERGRERGREREKQKGRER 444 Score = 38.9 bits (89), Expect = 0.003 Identities = 33/158 (20%), Positives = 70/158 (44%), Gaps = 13/158 (8%) Query: 6 KENEGKPENERNLESEGKPEDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEGEPGDEGQ 65 +E + E ER E + E E + E + +++ + E + RE E E + + Sbjct: 54 RERNRQKERERRREKR-QTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRE 112 Query: 66 LEDEGNQEKQGKSEGEDKPQSEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTD 125 + + +E+ + E E + + EG+ + + Q +R AE ++ +R+TDR Sbjct: 113 RDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAE----KERERQTDRERQ 168 Query: 126 DSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQ 163 + +++ +ER + +E R +E R+K+ Sbjct: 169 RQTERNRQKEREREKNRQE--------RRERERQREKE 198 Score = 38.9 bits (89), Expect = 0.003 Identities = 34/129 (26%), Positives = 55/129 (42%), Gaps = 5/129 (3%) Query: 7 ENEGKPENERNLESEGKPEDEGSTEDEGKSDEEEKP---DMEGKTECEGKREDEGEPGDE 63 E E + E ER+ +S + E+ D + E E+ D +G+ E E +RE E + E Sbjct: 368 ERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESE 427 Query: 64 GQLEDEGNQEKQGKSEGEDKPQSEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRG 123 E +EKQ E + + Q++ + Q K + R A V + + RG Sbjct: 428 RGRERGREREKQKGRERDRERQTDRQAGRQRKRSTLYVNPPPRTARSGVVQSDPNRPTRG 487 Query: 124 T--DDSPKD 130 SP+D Sbjct: 488 IRWKSSPED 496 Score = 38.1 bits (87), Expect = 0.005 Identities = 32/134 (23%), Positives = 61/134 (45%), Gaps = 4/134 (2%) Query: 6 KENEGKPENERNLESEGKPEDEGSTEDEGKSDEEE--KPDMEGKTECEGKREDEGEPGDE 63 +E E + E +R E + + E E + + + D E + EG+ + E +RE E E + Sbjct: 321 RERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQ 380 Query: 64 GQLE-DEGNQEKQGKSEGEDKPQSEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDR 122 E +E +++ + E + Q+E Q + E Q + R +E R +R+ + Sbjct: 381 SAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQK 440 Query: 123 GTDDSPKDSQEDLQ 136 G + ++ Q D Q Sbjct: 441 GR-ERDRERQTDRQ 453 Score = 36.6 bits (83), Expect = 0.015 Identities = 31/140 (22%), Positives = 64/140 (45%), Gaps = 6/140 (4%) Query: 27 EGSTEDEGKSDEEEKPDMEGKTECEGKREDEGEPGDEGQLEDEGNQEKQGKSEGEDKPQS 86 +G + + E E+ + +TE E R+ E + + + ++E+Q E E + Q+ Sbjct: 50 DGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQT 109 Query: 87 EGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTD-DSPKDSQEDLQ-ERHLSSEE 144 + + Q + E + +R E R+ +R DR TD ++ Q D + ER ++ Sbjct: 110 DRERDRQREKERNRQKERERETE----REGERGRDRQTDGQRERERQRDAEKERERQTDR 165 Query: 145 MMRECGDVSRAQEELRKKQK 164 + + +R +E R+K + Sbjct: 166 ERQRQTERNRQKEREREKNR 185 Score = 29.6 bits (65), Expect = 1.9 Identities = 22/105 (20%), Positives = 42/105 (40%), Gaps = 8/105 (7%) Query: 60 PGDEGQLEDEGNQEKQGKSEGEDKPQSEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRK 119 PG + G + ++G+D+ ++ K + R EKR E RK +R+ Sbjct: 31 PGSQESPRRRGLGQAHKDADGDDRERNRQK--------ERERRREKRQTERETDRKRERR 82 Query: 120 TDRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQK 164 ++ +E ++R E D R +E R+K++ Sbjct: 83 REKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKER 127 >gi|20270337 Leo1, Paf1/RNA polymerase II complex component, homolog [Homo sapiens] Length = 666 Score = 51.6 bits (122), Expect = 5e-07 Identities = 51/219 (23%), Positives = 87/219 (39%), Gaps = 25/219 (11%) Query: 7 ENEGKPENERNLESEGKPEDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEGEPG-DEGQ 65 E+EG + + SE + ++ ++DE K E+K D + + ++E G DE + Sbjct: 117 EDEGHRSDGGSHHSEAEGSEKAHSDDE-KWGREDKSDQSDDEKIQNSDDEERAQGSDEDK 175 Query: 66 LEDEGNQEKQGKSEGEDKPQSEGKPASQAKPESQPRAAEKRPA-------------EDYV 112 L++ + EK ++ E++PQ Q E + + ++RP E+ Sbjct: 176 LQNSDDDEKMQNTDDEERPQLSDDERQQLSEEEKANSDDERPVASDNDDEKQNSDDEEQP 235 Query: 113 PRKAKRKTDRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRA----QEELRKKQKMGGF 168 + K D+ P+ S E + RH EE + +R E LR K+K Sbjct: 236 QLSDEEKMQNSDDERPQASDE--EHRHSDDEEEQDHKSESARGSDSEDEVLRMKRKNAIA 293 Query: 169 HWMQRDVQDPFAPRGQRGVRGVRGGG---RGQKDLEDVP 204 + D D P+ G + GG D ED P Sbjct: 294 SDSEAD-SDTEVPKDNSGTMDLFGGADDISSGSDGEDKP 331 Score = 40.8 bits (94), Expect = 8e-04 Identities = 35/192 (18%), Positives = 78/192 (40%), Gaps = 37/192 (19%) Query: 2 EKLYKENEGKPENERNLESEGKPEDEGSTEDEGKS------------------DEEEKPD 43 EK + ++E +++ +S+ + E+ + D+EE+P Sbjct: 136 EKAHSDDEKWGREDKSDQSDDEKIQNSDDEERAQGSDEDKLQNSDDDEKMQNTDDEERPQ 195 Query: 44 MEGKTECEGKREDEGEPGDEGQLEDEGNQEKQGKSEGEDKPQSEGKPASQAKPESQPRAA 103 + + E++ DE + + + EKQ S+ E++PQ + Q + +P+A+ Sbjct: 196 LSDDERQQLSEEEKANSDDERPVASDNDDEKQ-NSDDEEQPQLSDEEKMQNSDDERPQAS 254 Query: 104 --EKRPAEDYVPRKAKRKTDRGTD----------------DSPKDSQEDLQERHLSSEEM 145 E R ++D + K ++ RG+D DS DS ++ + + + ++ Sbjct: 255 DEEHRHSDDEEEQDHKSESARGSDSEDEVLRMKRKNAIASDSEADSDTEVPKDNSGTMDL 314 Query: 146 MRECGDVSRAQE 157 D+S + Sbjct: 315 FGGADDISSGSD 326 Score = 40.0 bits (92), Expect = 0.001 Identities = 35/142 (24%), Positives = 56/142 (39%), Gaps = 13/142 (9%) Query: 19 ESEGKPEDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEGEPGDEGQLEDEGNQ----EK 74 E+ EDEG D G E EG + E G Q +DE Q E+ Sbjct: 111 EAPNDDEDEGHRSDGGSHHSEA----EGSEKAHSDDEKWGREDKSDQSDDEKIQNSDDEE 166 Query: 75 QGKSEGEDKPQS--EGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDR---GTDDSPK 129 + + EDK Q+ + + E +P+ ++ + KA +R +D K Sbjct: 167 RAQGSDEDKLQNSDDDEKMQNTDDEERPQLSDDERQQLSEEEKANSDDERPVASDNDDEK 226 Query: 130 DSQEDLQERHLSSEEMMRECGD 151 + +D ++ LS EE M+ D Sbjct: 227 QNSDDEEQPQLSDEEKMQNSDD 248 Score = 39.7 bits (91), Expect = 0.002 Identities = 37/160 (23%), Positives = 65/160 (40%), Gaps = 26/160 (16%) Query: 8 NEGKPENERNLESEGKPEDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEGEPGDEGQL- 66 + G+P N+ + EDEG++ G + E+ D + ED +P D Q Sbjct: 52 DSGQPSNKELFGDDS--EDEGASHHSGSDNHSERSDNRSEASERSDHEDN-DPSDVDQHS 108 Query: 67 --------EDEGNQEKQG----KSEGEDKPQSEGKP------ASQAKPESQPRAAEKRPA 108 EDEG++ G ++EG +K S+ + + Q+ E + ++ A Sbjct: 109 GSEAPNDDEDEGHRSDGGSHHSEAEGSEKAHSDDEKWGREDKSDQSDDEKIQNSDDEERA 168 Query: 109 EDYVPRKAKRKTD----RGTDDSPKDSQEDLQERHLSSEE 144 + K + D + TDD + D + + LS EE Sbjct: 169 QGSDEDKLQNSDDDEKMQNTDDEERPQLSDDERQQLSEEE 208 Score = 38.9 bits (89), Expect = 0.003 Identities = 26/139 (18%), Positives = 53/139 (38%), Gaps = 4/139 (2%) Query: 14 NERNLESEGKPEDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEGEPGDE----GQLEDE 69 ++ + E+E K D GS D + + + G + +R D G+P ++ EDE Sbjct: 10 SDADSEAERKDSDSGSDSDSDQENAASGSNASGSESDQDERGDSGQPSNKELFGDDSEDE 69 Query: 70 GNQEKQGKSEGEDKPQSEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPK 129 G G ++ + + + ++ E + + + P + + R S Sbjct: 70 GASHHSGSDNHSERSDNRSEASERSDHEDNDPSDVDQHSGSEAPNDDEDEGHRSDGGSHH 129 Query: 130 DSQEDLQERHLSSEEMMRE 148 E ++ H E+ RE Sbjct: 130 SEAEGSEKAHSDDEKWGRE 148 Score = 38.1 bits (87), Expect = 0.005 Identities = 40/184 (21%), Positives = 66/184 (35%), Gaps = 35/184 (19%) Query: 2 EKLYKENEGKPE--NERNLESEGKPEDEGSTEDEGKSDEEEKPDMEGKTECEGKREDE-- 57 EK ++E +P+ +E +++ + S E+ SD+EE+ D + ++ EDE Sbjct: 225 EKQNSDDEEQPQLSDEEKMQNSDDERPQASDEEHRHSDDEEEQDHKSESARGSDSEDEVL 284 Query: 58 -------------GEPGDEGQLEDEGNQEKQGK-------SEGEDKPQSEGKPASQAKPE 97 + E ++ G + G S+GEDKP + G+P + Sbjct: 285 RMKRKNAIASDSEADSDTEVPKDNSGTMDLFGGADDISSGSDGEDKPPTPGQPVDENGLP 344 Query: 98 SQPRAAEKRPAEDYVPRKAKRKTDRGTD-----------DSPKDSQEDLQERHLSSEEMM 146 + E P K TD G D P+ E EEM+ Sbjct: 345 QDQQEEEPIPETRIEVEIPKVNTDLGNDLYFVKLPNFLSVEPRPFDPQYYEDEFEDEEML 404 Query: 147 RECG 150 E G Sbjct: 405 DEEG 408 Score = 33.1 bits (74), Expect = 0.17 Identities = 28/151 (18%), Positives = 53/151 (35%), Gaps = 9/151 (5%) Query: 36 SDEEEKPDMEGKTECEGKREDEGEPGDEGQLEDEGNQEKQGKSEGEDKPQSEGKPASQA- 94 +D E+ + +E E K D G D Q G +D+ G+P+++ Sbjct: 2 ADMEDLFGSDADSEAERKDSDSGSDSDSDQENAASGSNASGSESDQDERGDSGQPSNKEL 61 Query: 95 -KPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDSQEDLQERHLSSE-------EMM 146 +S+ A D ++ +++ +D+ ++H SE E Sbjct: 62 FGDDSEDEGASHHSGSDNHSERSDNRSEASERSDHEDNDPSDVDQHSGSEAPNDDEDEGH 121 Query: 147 RECGDVSRAQEELRKKQKMGGFHWMQRDVQD 177 R G ++ E +K W + D D Sbjct: 122 RSDGGSHHSEAEGSEKAHSDDEKWGREDKSD 152 >gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapiens] Length = 436 Score = 51.2 bits (121), Expect = 6e-07 Identities = 42/165 (25%), Positives = 78/165 (47%), Gaps = 7/165 (4%) Query: 6 KENEGKPENERNL--ESEGKP-EDEGST-EDEGKSDEEEKPDMEGKTECEGKREDEGEPG 61 +E EG+ + E EG+ E EG E EG+ E+E+ E + + + + E GE Sbjct: 167 REQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQE 226 Query: 62 DEGQLEDE--GNQEKQGKSEGEDKPQSEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRK 119 ++ + ++E G QE+Q + + E + E + Q + + + E + +K + + Sbjct: 227 EQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTE 286 Query: 120 TDRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQK 164 + T + + +E +E+ EE MRE + R QEE KQ+ Sbjct: 287 QEEQTGEQEEQMREQ-EEQMREQEEQMREQEEQMREQEEQMGKQE 330 Score = 49.7 bits (117), Expect = 2e-06 Identities = 53/172 (30%), Positives = 80/172 (46%), Gaps = 27/172 (15%) Query: 6 KENEGKPENERNL--ESEGKP-EDEGST-EDEGKSDEEEKP--DMEGKT-ECEGK-REDE 57 +E EG+ + E EG+ E EG E EG+ E+E + EG+ E EG+ RE E Sbjct: 125 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 184 Query: 58 GEPGD-EGQL-EDEGNQEKQGKSEGEDKPQSEGKPASQAKPESQPRAAEKRPAEDYVPRK 115 G+ + EGQ+ E EG +Q + GE + Q + + + E Q R E++ E Sbjct: 185 GQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQ----- 239 Query: 116 AKRKTDRGTDDSPKDSQEDLQ---ERHLSSEEMMRECGDVSRAQEELRKKQK 164 ++ + +E +Q E+ EE MRE + R QEE KQK Sbjct: 240 ---------EEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQK 282 Score = 46.6 bits (109), Expect = 1e-05 Identities = 40/166 (24%), Positives = 75/166 (45%), Gaps = 9/166 (5%) Query: 2 EKLYKENEGKPENERNLESEGKP-EDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEGEP 60 E++ K+ E + E+ E E + E E ++ + E++ M + E GK+E++ Sbjct: 276 EQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWE 335 Query: 61 GDEGQLEDEGNQEKQGKSEGEDKPQSEGKPASQAKPESQPRAAEK--RPAEDYVPRKAKR 118 E E + KQ + GE + Q + + K E Q R E+ R E+ + ++ ++ Sbjct: 336 QKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQ 395 Query: 119 KTDRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQK 164 ++ K+ + +E+ EE M E + R QEE +QK Sbjct: 396 MGEQ------KEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQK 435 Score = 40.4 bits (93), Expect = 0.001 Identities = 34/168 (20%), Positives = 77/168 (45%), Gaps = 9/168 (5%) Query: 6 KENEGKPENERNLESE--GKPEDEGSTEDEGKSDEEE----KPDMEGKTECEGKREDEGE 59 +E G+ E + + E G+ E++ ++E ++EE + + K E + ++++E Sbjct: 205 EEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQM 264 Query: 60 PGDEGQLEDEGNQEKQGKSEGEDKPQSEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRK 119 E Q+ ++ Q + K + E + Q+ + + E Q R E++ E + + + Sbjct: 265 REQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEE 324 Query: 120 TDRGTDDSPKDSQEDL---QERHLSSEEMMRECGDVSRAQEELRKKQK 164 ++ + +E + +E+ EE M E + + QEE +KQ+ Sbjct: 325 QMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQE 372 Score = 40.4 bits (93), Expect = 0.001 Identities = 38/185 (20%), Positives = 84/185 (45%), Gaps = 19/185 (10%) Query: 2 EKLYKENEGKPENERNLESEGKPEDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEGEPG 61 E++ K+ E E E + + + E + + + ++ +K + + + + E RE E + Sbjct: 213 EQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMR 272 Query: 62 D-EGQLEDEGNQEKQGKSEGEDKPQSEGKPASQAKPESQPRAAEK--RPAEDYVPRKAKR 118 + E Q+ + Q +Q + GE + Q + + E Q R E+ R E+ + ++ ++ Sbjct: 273 EQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQ 332 Query: 119 KTDRGT------------DDSPKDSQEDLQ---ERHLSSEEMMRECGDVSRAQEE-LRKK 162 ++ ++ + +E +Q E+ EE MR+ + R QEE +RK+ Sbjct: 333 MWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQ 392 Query: 163 QKMGG 167 ++ G Sbjct: 393 EEQMG 397 Score = 37.4 bits (85), Expect = 0.009 Identities = 36/177 (20%), Positives = 81/177 (45%), Gaps = 13/177 (7%) Query: 7 ENEGKPENERNLESEGKPEDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEGEPGDEG-- 64 E EG+ + E G+ E++ ++E ++EE+ M + E G++E++ + +E Sbjct: 196 EQEGQMGEQE--EQMGEQEEQMQKQEEQMGEQEEQ--MRKQEEQMGEQEEQVQKQEEQVQ 251 Query: 65 -QLEDEGNQEKQGKSEGEDKPQSEG---KPASQAKPESQPRAAEKRPAEDYVPRKAKRKT 120 Q E QE+Q + + E + E K Q + E Q E++ E + + + Sbjct: 252 KQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQ 311 Query: 121 DRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRDVQD 177 R ++ ++ +E + ++ E+M + + +E++ K+++ G Q Q+ Sbjct: 312 MREQEEQMREQEEQMGKQ---EEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQE 365 >gi|239747174 PREDICTED: hypothetical protein XP_002343931, partial [Homo sapiens] Length = 213 Score = 51.2 bits (121), Expect = 6e-07 Identities = 39/163 (23%), Positives = 71/163 (43%), Gaps = 6/163 (3%) Query: 2 EKLYKENEGKPENERNLESEGKPEDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEGEPG 61 E + E + + + ERN E + E E T+ EG+ E + D + + E E +R+ E E Sbjct: 40 EDRHSERDRQRDRERNRERDRDREREKQTDREGERQRERERDRDRQRETERERDKERET- 98 Query: 62 DEGQLEDEGNQEKQGKSEGEDKPQSEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTD 121 + E + ++KQ + E E E + + E Q R E R+A+R+ + Sbjct: 99 -DRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTDRETDRERE----RQAERERE 153 Query: 122 RGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQK 164 G + +D + + E RE + R + R++Q+ Sbjct: 154 TGRERKTEDRHRERERERKRERERKRETKERERHTDMERERQR 196 Score = 39.3 bits (90), Expect = 0.002 Identities = 32/138 (23%), Positives = 66/138 (47%), Gaps = 10/138 (7%) Query: 6 KENEGKPENERNLESEGKPEDEGSTEDEGKSDEEEKPDMEGKTEC--EGKREDEGEPGDE 63 ++ E + + +R E+E + + E T+ ++D E + E + E + +RE + E G E Sbjct: 74 RQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRE 133 Query: 64 GQLEDEGNQEK--QGKSEGED----KPQSEGKPASQAKPESQPRAAEKRPAEDY--VPRK 115 Q + E ++E+ Q + E E K + + + + + R E + E + + R+ Sbjct: 134 RQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKERERHTDMERE 193 Query: 116 AKRKTDRGTDDSPKDSQE 133 +R+TDR D + +E Sbjct: 194 RQRETDRKRDRQRESERE 211 Score = 32.7 bits (73), Expect = 0.22 Identities = 30/149 (20%), Positives = 60/149 (40%), Gaps = 10/149 (6%) Query: 19 ESEGKPEDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEGEPGDEGQLEDEGNQEKQGKS 78 ++EG+ + + + + + D E E K ED D Q + E N+E+ Sbjct: 4 KTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDR-QRDRERNRERDRDR 62 Query: 79 EGEDKPQSEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTD---DSPKDSQEDL 135 E E + EG+ + + + R E R +R+TDR T+ + K + ++ Sbjct: 63 EREKQTDREGERQRERERD------RDRQRETERERDKERETDRHTETDRERQKQKEREM 116 Query: 136 QERHLSSEEMMRECGDVSRAQEELRKKQK 164 + E +E G + E ++++ Sbjct: 117 ERVRDREREKQKEMGRERQTDRETDRERE 145 Score = 31.6 bits (70), Expect = 0.50 Identities = 26/140 (18%), Positives = 61/140 (43%), Gaps = 13/140 (9%) Query: 30 TEDEGKSDEEEKPDMEGKTECEGKREDEGEPGDEGQLEDEGNQEKQGKSEGEDKPQSEGK 89 ++ EG+ E M+ + E + + E + E + ED ++ + D+ ++ + Sbjct: 3 SKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSE----RDRQRDRERNRER 58 Query: 90 PASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDSQEDLQERHLSS--EEMMR 147 + + + R E++ R+ +R DR + + +E +RH + E + Sbjct: 59 DRDREREKQTDREGERQ-------RERERDRDRQRETERERDKERETDRHTETDRERQKQ 111 Query: 148 ECGDVSRAQEELRKKQKMGG 167 + ++ R ++ R+KQK G Sbjct: 112 KEREMERVRDREREKQKEMG 131 >gi|116089325 splicing factor, arginine/serine-rich 12 isoform a [Homo sapiens] Length = 624 Score = 51.2 bits (121), Expect = 6e-07 Identities = 39/152 (25%), Positives = 66/152 (43%), Gaps = 4/152 (2%) Query: 6 KENEGKPENERNLESEGKPEDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEGEPGDEGQ 65 KE + + E ER E E K ++ G +D D+E + D E E + +RE E E + Sbjct: 391 KEKDREKEREREKERE-KEKERGKNKDR---DKEREKDREKDKEKDREREREKEHEKDRD 446 Query: 66 LEDEGNQEKQGKSEGEDKPQSEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTD 125 E E Q+K+ + E + + + K K + PR+ R+ +R+ R + Sbjct: 447 KEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSS 506 Query: 126 DSPKDSQEDLQERHLSSEEMMRECGDVSRAQE 157 SP+ S+ ++ S R D R +E Sbjct: 507 RSPRTSKTIKRKSSRSPSPRSRNKKDKKREKE 538 Score = 38.1 bits (87), Expect = 0.005 Identities = 35/162 (21%), Positives = 69/162 (42%), Gaps = 16/162 (9%) Query: 6 KENEGKPENERNLESEGKPEDEGSTEDEGK--SDEEEKPDMEGKTECEGKREDEGEPGDE 63 K ++ K + + S + +D ++ K S E+ ++ KR+D E E Sbjct: 327 KRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKE 386 Query: 64 GQLEDEGNQEKQGKSEGE-DKPQSEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDR 122 + E ++EK+ + E E +K + GK + K + R +K + R+ +++ ++ Sbjct: 387 KERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRE---REREKEHEK 443 Query: 123 GTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQK 164 D + Q+ +ER D S+ +E RKK K Sbjct: 444 DRDKEKEKEQDKEKERE----------KDRSKEIDEKRKKDK 475 >gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [Homo sapiens] Length = 508 Score = 51.2 bits (121), Expect = 6e-07 Identities = 39/152 (25%), Positives = 66/152 (43%), Gaps = 4/152 (2%) Query: 6 KENEGKPENERNLESEGKPEDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEGEPGDEGQ 65 KE + + E ER E E K ++ G +D D+E + D E E + +RE E E + Sbjct: 275 KEKDREKEREREKERE-KEKERGKNKDR---DKEREKDREKDKEKDREREREKEHEKDRD 330 Query: 66 LEDEGNQEKQGKSEGEDKPQSEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTD 125 E E Q+K+ + E + + + K K + PR+ R+ +R+ R + Sbjct: 331 KEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSS 390 Query: 126 DSPKDSQEDLQERHLSSEEMMRECGDVSRAQE 157 SP+ S+ ++ S R D R +E Sbjct: 391 RSPRTSKTIKRKSSRSPSPRSRNKKDKKREKE 422 Score = 38.1 bits (87), Expect = 0.005 Identities = 35/162 (21%), Positives = 69/162 (42%), Gaps = 16/162 (9%) Query: 6 KENEGKPENERNLESEGKPEDEGSTEDEGK--SDEEEKPDMEGKTECEGKREDEGEPGDE 63 K ++ K + + S + +D ++ K S E+ ++ KR+D E E Sbjct: 211 KRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKE 270 Query: 64 GQLEDEGNQEKQGKSEGE-DKPQSEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDR 122 + E ++EK+ + E E +K + GK + K + R +K + R+ +++ ++ Sbjct: 271 KERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRE---REREKEHEK 327 Query: 123 GTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQK 164 D + Q+ +ER D S+ +E RKK K Sbjct: 328 DRDKEKEKEQDKEKERE----------KDRSKEIDEKRKKDK 359 >gi|115529449 upstream binding transcription factor, RNA polymerase I isoform b [Homo sapiens] Length = 727 Score = 50.4 bits (119), Expect = 1e-06 Identities = 31/99 (31%), Positives = 46/99 (46%), Gaps = 6/99 (6%) Query: 1 MEKLYKENEGKPENERNLESEGKPEDEGSTEDEGKSDEEEKPD-----MEGKTECEGKRE 55 M KL N +SE + +DE +DE + +EEE + +G E E Sbjct: 619 MTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSE 678 Query: 56 DEGEPGDEGQLEDEGNQEKQGKSEGEDKPQSEGKPASQA 94 DE E GDE + +DE + + E ED +SEG +S + Sbjct: 679 DESEDGDENEEDDEDEDDDEDDDEDEDN-ESEGSSSSSS 716 Score = 41.2 bits (95), Expect = 6e-04 Identities = 19/81 (23%), Positives = 39/81 (48%) Query: 6 KENEGKPENERNLESEGKPEDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEGEPGDEGQ 65 +E++ + E++ + + E + ++ G + ++G E + E + E + +DE E DE Sbjct: 641 EEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDD 700 Query: 66 LEDEGNQEKQGKSEGEDKPQS 86 EDE N+ + S S Sbjct: 701 DEDEDNESEGSSSSSSSSGDS 721 Score = 28.9 bits (63), Expect = 3.2 Identities = 16/53 (30%), Positives = 25/53 (47%), Gaps = 3/53 (5%) Query: 7 ENEGKPENERNLESEGKPEDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEGE 59 E+ + E+E E+E EDE ED+ DE+E + EG + D + Sbjct: 674 ESSSEDESEDGDENEEDDEDEDDDEDD---DEDEDNESEGSSSSSSSSGDSSD 723 Score = 28.1 bits (61), Expect = 5.5 Identities = 22/105 (20%), Positives = 48/105 (45%), Gaps = 15/105 (14%) Query: 30 TEDEGKSDEEEKPDMEGKTECEGKREDEGEPGDEGQLEDEGNQEKQGKSEGEDKPQSEGK 89 T+ G + + + ++ K+E E ED+ E D+ + EDE ++ + ED G Sbjct: 620 TKLRGPNPKSSRTTLQSKSESE---EDDEEDEDD-EDEDEEEEDDENGDSSED-----GG 670 Query: 90 PASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDSQED 134 +S++ E + ++ +D + + D DD +D++ + Sbjct: 671 DSSESSSEDESEDGDENEEDD------EDEDDDEDDDEDEDNESE 709 >gi|115529451 upstream binding transcription factor, RNA polymerase I isoform b [Homo sapiens] Length = 727 Score = 50.4 bits (119), Expect = 1e-06 Identities = 31/99 (31%), Positives = 46/99 (46%), Gaps = 6/99 (6%) Query: 1 MEKLYKENEGKPENERNLESEGKPEDEGSTEDEGKSDEEEKPD-----MEGKTECEGKRE 55 M KL N +SE + +DE +DE + +EEE + +G E E Sbjct: 619 MTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSE 678 Query: 56 DEGEPGDEGQLEDEGNQEKQGKSEGEDKPQSEGKPASQA 94 DE E GDE + +DE + + E ED +SEG +S + Sbjct: 679 DESEDGDENEEDDEDEDDDEDDDEDEDN-ESEGSSSSSS 716 Score = 41.2 bits (95), Expect = 6e-04 Identities = 19/81 (23%), Positives = 39/81 (48%) Query: 6 KENEGKPENERNLESEGKPEDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEGEPGDEGQ 65 +E++ + E++ + + E + ++ G + ++G E + E + E + +DE E DE Sbjct: 641 EEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDD 700 Query: 66 LEDEGNQEKQGKSEGEDKPQS 86 EDE N+ + S S Sbjct: 701 DEDEDNESEGSSSSSSSSGDS 721 Score = 28.9 bits (63), Expect = 3.2 Identities = 16/53 (30%), Positives = 25/53 (47%), Gaps = 3/53 (5%) Query: 7 ENEGKPENERNLESEGKPEDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEGE 59 E+ + E+E E+E EDE ED+ DE+E + EG + D + Sbjct: 674 ESSSEDESEDGDENEEDDEDEDDDEDD---DEDEDNESEGSSSSSSSSGDSSD 723 Score = 28.1 bits (61), Expect = 5.5 Identities = 22/105 (20%), Positives = 48/105 (45%), Gaps = 15/105 (14%) Query: 30 TEDEGKSDEEEKPDMEGKTECEGKREDEGEPGDEGQLEDEGNQEKQGKSEGEDKPQSEGK 89 T+ G + + + ++ K+E E ED+ E D+ + EDE ++ + ED G Sbjct: 620 TKLRGPNPKSSRTTLQSKSESE---EDDEEDEDD-EDEDEEEEDDENGDSSED-----GG 670 Query: 90 PASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDSQED 134 +S++ E + ++ +D + + D DD +D++ + Sbjct: 671 DSSESSSEDESEDGDENEEDD------EDEDDDEDDDEDEDNESE 709 >gi|7657671 upstream binding transcription factor, RNA polymerase I isoform a [Homo sapiens] Length = 764 Score = 50.4 bits (119), Expect = 1e-06 Identities = 31/99 (31%), Positives = 46/99 (46%), Gaps = 6/99 (6%) Query: 1 MEKLYKENEGKPENERNLESEGKPEDEGSTEDEGKSDEEEKPD-----MEGKTECEGKRE 55 M KL N +SE + +DE +DE + +EEE + +G E E Sbjct: 656 MTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSE 715 Query: 56 DEGEPGDEGQLEDEGNQEKQGKSEGEDKPQSEGKPASQA 94 DE E GDE + +DE + + E ED +SEG +S + Sbjct: 716 DESEDGDENEEDDEDEDDDEDDDEDEDN-ESEGSSSSSS 753 Score = 41.2 bits (95), Expect = 6e-04 Identities = 19/81 (23%), Positives = 39/81 (48%) Query: 6 KENEGKPENERNLESEGKPEDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEGEPGDEGQ 65 +E++ + E++ + + E + ++ G + ++G E + E + E + +DE E DE Sbjct: 678 EEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDD 737 Query: 66 LEDEGNQEKQGKSEGEDKPQS 86 EDE N+ + S S Sbjct: 738 DEDEDNESEGSSSSSSSSGDS 758 Score = 28.9 bits (63), Expect = 3.2 Identities = 16/53 (30%), Positives = 25/53 (47%), Gaps = 3/53 (5%) Query: 7 ENEGKPENERNLESEGKPEDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEGE 59 E+ + E+E E+E EDE ED+ DE+E + EG + D + Sbjct: 711 ESSSEDESEDGDENEEDDEDEDDDEDD---DEDEDNESEGSSSSSSSSGDSSD 760 Score = 28.1 bits (61), Expect = 5.5 Identities = 22/105 (20%), Positives = 48/105 (45%), Gaps = 15/105 (14%) Query: 30 TEDEGKSDEEEKPDMEGKTECEGKREDEGEPGDEGQLEDEGNQEKQGKSEGEDKPQSEGK 89 T+ G + + + ++ K+E E ED+ E D+ + EDE ++ + ED G Sbjct: 657 TKLRGPNPKSSRTTLQSKSESE---EDDEEDEDD-EDEDEEEEDDENGDSSED-----GG 707 Query: 90 PASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDSQED 134 +S++ E + ++ +D + + D DD +D++ + Sbjct: 708 DSSESSSEDESEDGDENEEDD------EDEDDDEDDDEDEDNESE 746 >gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] Length = 1020 Score = 49.3 bits (116), Expect = 2e-06 Identities = 40/140 (28%), Positives = 64/140 (45%), Gaps = 4/140 (2%) Query: 21 EGKPEDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEGEPGDEGQLEDEGNQEKQGKSEG 80 E + E+ TE+ + +E+E + EGK E EG E+E E G+E + + E Sbjct: 458 EEQTEETQVTEEVTEEEEKEAKEEEGKEE-EGGEEEEAEGGEEETKSPPAEEAASPEKEA 516 Query: 81 EDKPQSEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDSQEDLQERHL 140 + + E K ++AK + A K PAE P KAK + SP +++ +E Sbjct: 517 KSPVKEEAKSPAEAKSPEKEEA--KSPAEVKSPEKAKSPA-KEEAKSPPEAKSPEKEEAK 573 Query: 141 SSEEMMRECGDVSRAQEELR 160 S E+ S A+EE + Sbjct: 574 SPAEVKSPEKAKSPAKEEAK 593 Score = 47.4 bits (111), Expect = 9e-06 Identities = 39/176 (22%), Positives = 73/176 (41%), Gaps = 13/176 (7%) Query: 2 EKLYKENEGKPENERNLESEGKPEDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEGEPG 61 E+ E E E+ + E E+EG E+E + EEE + ++E + Sbjct: 462 EETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVK 521 Query: 62 DEGQ--LEDEGNQEKQGKSEGEDKPQSEGKPASQAKPESQPRAAE------KRPAEDYVP 113 +E + E + ++++ KS E K + K ++ + +S P A K PAE P Sbjct: 522 EEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSP 581 Query: 114 RKAKRKTDRGTDD-----SPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQK 164 KAK SP+ ++ ++E S E + +++ E++ +K Sbjct: 582 EKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEK 637 Score = 45.1 bits (105), Expect = 4e-05 Identities = 35/130 (26%), Positives = 55/130 (42%), Gaps = 10/130 (7%) Query: 9 EGKPENERNLESEGKPEDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEG---EPGDEGQ 65 E K E + + PE E + E K D + K KTE K D+ EP + Sbjct: 891 EAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKE----KTEVAKKEPDDAKAKEPSKPAE 946 Query: 66 LEDEGNQEKQGKSEGEDKPQSEGKPASQAKPESQPRAAEKRPAEDYVPRKAK-RKTDRGT 124 ++ ++K K E KP E KP ++AK + + K P++ + K TD+ Sbjct: 947 KKEAAPEKKDTKEEKAKKP--EEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKD 1004 Query: 125 DDSPKDSQED 134 P+ + ED Sbjct: 1005 SKPPEKATED 1014 Score = 38.5 bits (88), Expect = 0.004 Identities = 34/148 (22%), Positives = 68/148 (45%), Gaps = 3/148 (2%) Query: 18 LESEGKPEDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEGEPGDEGQLEDEGNQEK-QG 76 ++SE K + +E E EE+ + + E + E E + +EG+ E+ G +E+ +G Sbjct: 438 VKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKE-EEGKEEEGGEEEEAEG 496 Query: 77 KSEGEDKPQSEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDSQEDLQ 136 E P +E + + + +S + K PAE P K + K+ SP+ ++ + Sbjct: 497 GEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEV-KSPEKAKSPAK 555 Query: 137 ERHLSSEEMMRECGDVSRAQEELRKKQK 164 E S E + +++ E++ +K Sbjct: 556 EEAKSPPEAKSPEKEEAKSPAEVKSPEK 583 Score = 38.5 bits (88), Expect = 0.004 Identities = 38/160 (23%), Positives = 68/160 (42%), Gaps = 10/160 (6%) Query: 6 KENEGKPENERNLESEGKP-EDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEGEPGDEG 64 KE P ++ E P ++E + E KS E+E E K+ E K ++ + Sbjct: 535 KEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKE----EAKSPAEVKSPEKAK----S 586 Query: 65 QLEDEGNQEKQGKSEGEDKPQSEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGT 124 ++E + KS + K + + S A+ +S + K PAE P KAK T + Sbjct: 587 PAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPT-KEE 645 Query: 125 DDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQK 164 SP+ ++ +E S E+ +++ E+ + K Sbjct: 646 AKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVK 685 Score = 37.7 bits (86), Expect = 0.007 Identities = 39/175 (22%), Positives = 73/175 (41%), Gaps = 22/175 (12%) Query: 6 KENEGKPENERNLESEGKPEDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEG------E 59 KE K E + ++ E KP++ E K++EE+ P E + +++E + Sbjct: 812 KEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPK 871 Query: 60 PGDEGQLEDEGNQEKQG-----KSEGEDK-----PQSEGKPASQAKPESQPRAAEKRPAE 109 P E + E + K+ K E EDK P+ E + K +++P+ EK Sbjct: 872 PKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPK--EKTEVA 929 Query: 110 DYVPRKAKRKTDRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQK 164 P AK K P + +E E+ + EE ++ + + + + ++ K Sbjct: 930 KKEPDDAKAK----EPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDK 980 Score = 32.7 bits (73), Expect = 0.22 Identities = 36/166 (21%), Positives = 69/166 (41%), Gaps = 17/166 (10%) Query: 6 KENEGKPENERNLESEGKPEDEGS---TEDEGKSDEEEKPDMEGKTECEGKREDEGEPGD 62 KE PE ++ E E E + + E KS E+ K ++ + + K Sbjct: 643 KEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKA-------- 694 Query: 63 EGQLEDEGNQEKQGKSEGEDKPQSEGKPASQAKPESQPRAAEKRPAEDYV--PRKAKRKT 120 + +++E ++ KS +++ +S K S K E++ K P ++ P KAK Sbjct: 695 KSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPE 754 Query: 121 DRGTDD--SPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQK 164 T D SP+ +E +++ + S +EE++ +K Sbjct: 755 KAKTLDVKSPEAKTPAKEEARSPADKFPEKA--KSPVKEEVKSPEK 798 Score = 31.6 bits (70), Expect = 0.50 Identities = 19/88 (21%), Positives = 38/88 (43%), Gaps = 3/88 (3%) Query: 11 KPENERNLESEGKPEDEGSTEDEGKSDEEEK---PDMEGKTECEGKREDEGEPGDEGQLE 67 K ++ + KP ++ E K +EEK P+ + KTE + K +D+ + + + Sbjct: 931 KEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPK 990 Query: 68 DEGNQEKQGKSEGEDKPQSEGKPASQAK 95 E ++ + + KP + AK Sbjct: 991 AEKAEKSSSTDQKDSKPPEKATEDKAAK 1018 Score = 31.2 bits (69), Expect = 0.65 Identities = 36/170 (21%), Positives = 73/170 (42%), Gaps = 25/170 (14%) Query: 7 ENEGKPENERNLESEGKPEDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEGEPGDEGQL 66 E PE + L+ + PE + ++E +S ++ P+ K + K E + + L Sbjct: 748 EKAKSPEKAKTLDVKS-PEAKTPAKEEARSPADKFPE---KAKSPVKEEVKSPEKAKSPL 803 Query: 67 EDEGN---------QEKQGKSEGEDKPQSEGKPASQAKPESQPRAAEKRPAEDYVPRKAK 117 +++ +E + + E+KPQ + K + P+ AE+ A K + Sbjct: 804 KEDAKAPEKEIPKKEEVKSPVKEEEKPQ-------EVKVKEPPKKAEEEKAP--ATPKTE 854 Query: 118 RKTDRGTDDSPKDS--QEDLQERHLSSEEMMRECGDVSRAQEELRKKQKM 165 K D +++PK + ++E+ + E +E V +EE K+K+ Sbjct: 855 EKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKE-SKVEAKKEEAEDKKKV 903 Score = 28.1 bits (61), Expect = 5.5 Identities = 15/75 (20%), Positives = 33/75 (44%), Gaps = 1/75 (1%) Query: 6 KENEGKPENERNLESEGK-PEDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEGEPGDEG 64 ++ E PE + E + K PE++ TE + K D++ K + E + + Sbjct: 946 EKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDS 1005 Query: 65 QLEDEGNQEKQGKSE 79 + ++ ++K K + Sbjct: 1006 KPPEKATEDKAAKGK 1020 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.301 0.127 0.356 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 10,514,708 Number of Sequences: 37866 Number of extensions: 639550 Number of successful extensions: 18299 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 716 Number of HSP's successfully gapped in prelim test: 811 Number of HSP's that attempted gapping in prelim test: 4118 Number of HSP's gapped (non-prelim): 7984 length of query: 206 length of database: 18,247,518 effective HSP length: 97 effective length of query: 109 effective length of database: 14,574,516 effective search space: 1588622244 effective search space used: 1588622244 T: 11 A: 40 X1: 17 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 43 (21.6 bits) S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.