Guide to the Human Genome
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Search of human proteins with 61102725

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|61102725 la related protein isoform 2 [Homo sapiens]
         (1096 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|61102725 la related protein isoform 2 [Homo sapiens]              2272   0.0  
gi|39725634 la related protein isoform 1 [Homo sapiens]              1973   0.0  
gi|30061567 La ribonucleoprotein domain family member 2 isoform ...  1038   0.0  
gi|30061565 La ribonucleoprotein domain family member 2 isoform ...   514   e-145
gi|30061569 La ribonucleoprotein domain family member 2 isoform ...   293   8e-79
gi|239753842 PREDICTED: similar to hCG2040199 [Homo sapiens]          100   1e-20
gi|169166778 PREDICTED: similar to hCG2040199 [Homo sapiens]          100   1e-20
gi|169166363 PREDICTED: similar to hCG2040199 [Homo sapiens]          100   1e-20
gi|40353738 c-Mpl binding protein isoform a [Homo sapiens]             74   1e-12
gi|40353736 c-Mpl binding protein isoform c [Homo sapiens]             74   1e-12
gi|40353740 c-Mpl binding protein isoform b [Homo sapiens]             74   1e-12
gi|10835067 autoantigen La [Homo sapiens]                              67   1e-10
gi|109809739 La ribonucleoprotein domain family, member 7 [Homo ...    58   4e-08
gi|109809741 La ribonucleoprotein domain family, member 7 [Homo ...    58   4e-08
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre...    57   1e-07
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H...    55   3e-07
gi|57634536 La ribonucleoprotein domain family, member 4B [Homo ...    55   4e-07
gi|37537710 La ribonucleoprotein domain family, member 6 isoform...    54   1e-06
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]      53   1e-06
gi|116256464 hypothetical protein LOC343990 [Homo sapiens]             52   3e-06
gi|150170670 piccolo isoform 2 [Homo sapiens]                          51   7e-06
gi|150378539 piccolo isoform 1 [Homo sapiens]                          51   7e-06
gi|39812378 RAN binding protein 9 [Homo sapiens]                       50   1e-05
gi|158854042 hypothetical protein LOC222183 [Homo sapiens]             49   3e-05
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     49   3e-05
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         49   3e-05
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ...    48   4e-05
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ...    48   4e-05
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]          48   6e-05
gi|149158690 HLA-B associated transcript-2 [Homo sapiens]              48   6e-05

>gi|61102725 la related protein isoform 2 [Homo sapiens]
          Length = 1096

 Score = 2272 bits (5888), Expect = 0.0
 Identities = 1096/1096 (100%), Positives = 1096/1096 (100%)

Query: 1    MATQVEPLLPGGATLLQAEEHGGLVRKKPPPAPEGKGEPGPNDVRGGEPDGSARRPRPPC 60
            MATQVEPLLPGGATLLQAEEHGGLVRKKPPPAPEGKGEPGPNDVRGGEPDGSARRPRPPC
Sbjct: 1    MATQVEPLLPGGATLLQAEEHGGLVRKKPPPAPEGKGEPGPNDVRGGEPDGSARRPRPPC 60

Query: 61   AKPHKEGTGQQERESPRPLQLPGAEGPAISDGEEGGGEPGAGGGAAGAAGAGRRDFVEAP 120
            AKPHKEGTGQQERESPRPLQLPGAEGPAISDGEEGGGEPGAGGGAAGAAGAGRRDFVEAP
Sbjct: 61   AKPHKEGTGQQERESPRPLQLPGAEGPAISDGEEGGGEPGAGGGAAGAAGAGRRDFVEAP 120

Query: 121  PPKVNPWTKNALPPVLTTVNGQSPPEHSAPAKVVRAAVPKQRKGSKVGDFGDAINWPTPG 180
            PPKVNPWTKNALPPVLTTVNGQSPPEHSAPAKVVRAAVPKQRKGSKVGDFGDAINWPTPG
Sbjct: 121  PPKVNPWTKNALPPVLTTVNGQSPPEHSAPAKVVRAAVPKQRKGSKVGDFGDAINWPTPG 180

Query: 181  EIAHKSVQPQSHKPQPTRKLPPKKDMKEQEKGEGSDSKESPKTKSDESGEEKNGDEDCQR 240
            EIAHKSVQPQSHKPQPTRKLPPKKDMKEQEKGEGSDSKESPKTKSDESGEEKNGDEDCQR
Sbjct: 181  EIAHKSVQPQSHKPQPTRKLPPKKDMKEQEKGEGSDSKESPKTKSDESGEEKNGDEDCQR 240

Query: 241  GGQKKKGNKHKWVPLQIDMKPEVPREKLASRPTRPPEPRHIPANRGEIKGSESATYVPVA 300
            GGQKKKGNKHKWVPLQIDMKPEVPREKLASRPTRPPEPRHIPANRGEIKGSESATYVPVA
Sbjct: 241  GGQKKKGNKHKWVPLQIDMKPEVPREKLASRPTRPPEPRHIPANRGEIKGSESATYVPVA 300

Query: 301  PPTPAWQPEIKPEPAWHDQDETSSVKSDGAGGARASFRGRGRGRGRGRGRGRGGTRTHFD 360
            PPTPAWQPEIKPEPAWHDQDETSSVKSDGAGGARASFRGRGRGRGRGRGRGRGGTRTHFD
Sbjct: 301  PPTPAWQPEIKPEPAWHDQDETSSVKSDGAGGARASFRGRGRGRGRGRGRGRGGTRTHFD 360

Query: 361  YQFGYRKFDGVEGPRTPKYMNNITYYFDNVSSTELYSVDQELLKDYIKRQIEYYFSVDNL 420
            YQFGYRKFDGVEGPRTPKYMNNITYYFDNVSSTELYSVDQELLKDYIKRQIEYYFSVDNL
Sbjct: 361  YQFGYRKFDGVEGPRTPKYMNNITYYFDNVSSTELYSVDQELLKDYIKRQIEYYFSVDNL 420

Query: 421  ERDFFLRRKMDADGFLPITLIASFHRVQALTTDISLIFAALKDSKVVEIVDEKVRRREEP 480
            ERDFFLRRKMDADGFLPITLIASFHRVQALTTDISLIFAALKDSKVVEIVDEKVRRREEP
Sbjct: 421  ERDFFLRRKMDADGFLPITLIASFHRVQALTTDISLIFAALKDSKVVEIVDEKVRRREEP 480

Query: 481  EKWPLPPIVDYSQTDFSQLLNCPEFVPRQHYQKETESAPGSPRAVTPVPTKTEEVSNLKT 540
            EKWPLPPIVDYSQTDFSQLLNCPEFVPRQHYQKETESAPGSPRAVTPVPTKTEEVSNLKT
Sbjct: 481  EKWPLPPIVDYSQTDFSQLLNCPEFVPRQHYQKETESAPGSPRAVTPVPTKTEEVSNLKT 540

Query: 541  LPKGLSASLPDLDSENWIEVKKRPRPSPARPKKSEESRFSHLTSLPQQLPSQQLMSKDQD 600
            LPKGLSASLPDLDSENWIEVKKRPRPSPARPKKSEESRFSHLTSLPQQLPSQQLMSKDQD
Sbjct: 541  LPKGLSASLPDLDSENWIEVKKRPRPSPARPKKSEESRFSHLTSLPQQLPSQQLMSKDQD 600

Query: 601  EQEELDFLFDEEMEQMDGRKNTFTAWSDEESDYEIDDRDVNKILIVTQTPHYMRRHPGGD 660
            EQEELDFLFDEEMEQMDGRKNTFTAWSDEESDYEIDDRDVNKILIVTQTPHYMRRHPGGD
Sbjct: 601  EQEELDFLFDEEMEQMDGRKNTFTAWSDEESDYEIDDRDVNKILIVTQTPHYMRRHPGGD 660

Query: 661  RTGNHTSRAKMSAELAKVINDGLFYYEQDLWAEKFEPEYSQIKQEVENFKKVNMISREQF 720
            RTGNHTSRAKMSAELAKVINDGLFYYEQDLWAEKFEPEYSQIKQEVENFKKVNMISREQF
Sbjct: 661  RTGNHTSRAKMSAELAKVINDGLFYYEQDLWAEKFEPEYSQIKQEVENFKKVNMISREQF 720

Query: 721  DTLTPEPPVDPNQEVPPGPPRFQQVPTDALANKLFGAPEPSTIARSLPTTVPESPNYRNT 780
            DTLTPEPPVDPNQEVPPGPPRFQQVPTDALANKLFGAPEPSTIARSLPTTVPESPNYRNT
Sbjct: 721  DTLTPEPPVDPNQEVPPGPPRFQQVPTDALANKLFGAPEPSTIARSLPTTVPESPNYRNT 780

Query: 781  RTPRTPRTPQLKDSSQTSRFYPVVKEGRTLDAKMPRKRKTRHSSNPPLESHVGWVMDSRE 840
            RTPRTPRTPQLKDSSQTSRFYPVVKEGRTLDAKMPRKRKTRHSSNPPLESHVGWVMDSRE
Sbjct: 781  RTPRTPRTPQLKDSSQTSRFYPVVKEGRTLDAKMPRKRKTRHSSNPPLESHVGWVMDSRE 840

Query: 841  HRPRTASISSSPSEGTPTVGSYGCTPQSLPKFQHPSHELLKENGFTQHVYHKYRRRCLNE 900
            HRPRTASISSSPSEGTPTVGSYGCTPQSLPKFQHPSHELLKENGFTQHVYHKYRRRCLNE
Sbjct: 841  HRPRTASISSSPSEGTPTVGSYGCTPQSLPKFQHPSHELLKENGFTQHVYHKYRRRCLNE 900

Query: 901  RKRLGIGQSQEMNTLFRFWSFFLRDHFNKKMYEEFKQLALEDAKEGYRYGLECLFRYYSY 960
            RKRLGIGQSQEMNTLFRFWSFFLRDHFNKKMYEEFKQLALEDAKEGYRYGLECLFRYYSY
Sbjct: 901  RKRLGIGQSQEMNTLFRFWSFFLRDHFNKKMYEEFKQLALEDAKEGYRYGLECLFRYYSY 960

Query: 961  GLEKKFRLDIFKDFQEETVKDYEAGQLYGLEKFWAFLKYSKAKNLDIDPKLQEYLGKFRR 1020
            GLEKKFRLDIFKDFQEETVKDYEAGQLYGLEKFWAFLKYSKAKNLDIDPKLQEYLGKFRR
Sbjct: 961  GLEKKFRLDIFKDFQEETVKDYEAGQLYGLEKFWAFLKYSKAKNLDIDPKLQEYLGKFRR 1020

Query: 1021 LEDFRVDPPMGEEGNHKRHSVVAGGGGGEGRKRCPSQSSSRPAAMISQPPTPPTGQPVRE 1080
            LEDFRVDPPMGEEGNHKRHSVVAGGGGGEGRKRCPSQSSSRPAAMISQPPTPPTGQPVRE
Sbjct: 1021 LEDFRVDPPMGEEGNHKRHSVVAGGGGGEGRKRCPSQSSSRPAAMISQPPTPPTGQPVRE 1080

Query: 1081 DAKWTSQHSNTQTLGK 1096
            DAKWTSQHSNTQTLGK
Sbjct: 1081 DAKWTSQHSNTQTLGK 1096


>gi|39725634 la related protein isoform 1 [Homo sapiens]
          Length = 1019

 Score = 1973 bits (5112), Expect = 0.0
 Identities = 960/986 (97%), Positives = 964/986 (97%), Gaps = 1/986 (0%)

Query: 112  GRRDFVE-APPPKVNPWTKNALPPVLTTVNGQSPPEHSAPAKVVRAAVPKQRKGSKVGDF 170
            GR++ V  A  P+  P      P     +   S PEHSAPAKVVRAAVPKQRKGSKVGDF
Sbjct: 34   GRKNSVALAAAPRKEPTGDREKPLPFPVLAPFSNPEHSAPAKVVRAAVPKQRKGSKVGDF 93

Query: 171  GDAINWPTPGEIAHKSVQPQSHKPQPTRKLPPKKDMKEQEKGEGSDSKESPKTKSDESGE 230
            GDAINWPTPGEIAHKSVQPQSHKPQPTRKLPPKKDMKEQEKGEGSDSKESPKTKSDESGE
Sbjct: 94   GDAINWPTPGEIAHKSVQPQSHKPQPTRKLPPKKDMKEQEKGEGSDSKESPKTKSDESGE 153

Query: 231  EKNGDEDCQRGGQKKKGNKHKWVPLQIDMKPEVPREKLASRPTRPPEPRHIPANRGEIKG 290
            EKNGDEDCQRGGQKKKGNKHKWVPLQIDMKPEVPREKLASRPTRPPEPRHIPANRGEIKG
Sbjct: 154  EKNGDEDCQRGGQKKKGNKHKWVPLQIDMKPEVPREKLASRPTRPPEPRHIPANRGEIKG 213

Query: 291  SESATYVPVAPPTPAWQPEIKPEPAWHDQDETSSVKSDGAGGARASFRGRGRGRGRGRGR 350
            SESATYVPVAPPTPAWQPEIKPEPAWHDQDETSSVKSDGAGGARASFRGRGRGRGRGRGR
Sbjct: 214  SESATYVPVAPPTPAWQPEIKPEPAWHDQDETSSVKSDGAGGARASFRGRGRGRGRGRGR 273

Query: 351  GRGGTRTHFDYQFGYRKFDGVEGPRTPKYMNNITYYFDNVSSTELYSVDQELLKDYIKRQ 410
            GRGGTRTHFDYQFGYRKFDGVEGPRTPKYMNNITYYFDNVSSTELYSVDQELLKDYIKRQ
Sbjct: 274  GRGGTRTHFDYQFGYRKFDGVEGPRTPKYMNNITYYFDNVSSTELYSVDQELLKDYIKRQ 333

Query: 411  IEYYFSVDNLERDFFLRRKMDADGFLPITLIASFHRVQALTTDISLIFAALKDSKVVEIV 470
            IEYYFSVDNLERDFFLRRKMDADGFLPITLIASFHRVQALTTDISLIFAALKDSKVVEIV
Sbjct: 334  IEYYFSVDNLERDFFLRRKMDADGFLPITLIASFHRVQALTTDISLIFAALKDSKVVEIV 393

Query: 471  DEKVRRREEPEKWPLPPIVDYSQTDFSQLLNCPEFVPRQHYQKETESAPGSPRAVTPVPT 530
            DEKVRRREEPEKWPLPPIVDYSQTDFSQLLNCPEFVPRQHYQKETESAPGSPRAVTPVPT
Sbjct: 394  DEKVRRREEPEKWPLPPIVDYSQTDFSQLLNCPEFVPRQHYQKETESAPGSPRAVTPVPT 453

Query: 531  KTEEVSNLKTLPKGLSASLPDLDSENWIEVKKRPRPSPARPKKSEESRFSHLTSLPQQLP 590
            KTEEVSNLKTLPKGLSASLPDLDSENWIEVKKRPRPSPARPKKSEESRFSHLTSLPQQLP
Sbjct: 454  KTEEVSNLKTLPKGLSASLPDLDSENWIEVKKRPRPSPARPKKSEESRFSHLTSLPQQLP 513

Query: 591  SQQLMSKDQDEQEELDFLFDEEMEQMDGRKNTFTAWSDEESDYEIDDRDVNKILIVTQTP 650
            SQQLMSKDQDEQEELDFLFDEEMEQMDGRKNTFTAWSDEESDYEIDDRDVNKILIVTQTP
Sbjct: 514  SQQLMSKDQDEQEELDFLFDEEMEQMDGRKNTFTAWSDEESDYEIDDRDVNKILIVTQTP 573

Query: 651  HYMRRHPGGDRTGNHTSRAKMSAELAKVINDGLFYYEQDLWAEKFEPEYSQIKQEVENFK 710
            HYMRRHPGGDRTGNHTSRAKMSAELAKVINDGLFYYEQDLWAEKFEPEYSQIKQEVENFK
Sbjct: 574  HYMRRHPGGDRTGNHTSRAKMSAELAKVINDGLFYYEQDLWAEKFEPEYSQIKQEVENFK 633

Query: 711  KVNMISREQFDTLTPEPPVDPNQEVPPGPPRFQQVPTDALANKLFGAPEPSTIARSLPTT 770
            KVNMISREQFDTLTPEPPVDPNQEVPPGPPRFQQVPTDALANKLFGAPEPSTIARSLPTT
Sbjct: 634  KVNMISREQFDTLTPEPPVDPNQEVPPGPPRFQQVPTDALANKLFGAPEPSTIARSLPTT 693

Query: 771  VPESPNYRNTRTPRTPRTPQLKDSSQTSRFYPVVKEGRTLDAKMPRKRKTRHSSNPPLES 830
            VPESPNYRNTRTPRTPRTPQLKDSSQTSRFYPVVKEGRTLDAKMPRKRKTRHSSNPPLES
Sbjct: 694  VPESPNYRNTRTPRTPRTPQLKDSSQTSRFYPVVKEGRTLDAKMPRKRKTRHSSNPPLES 753

Query: 831  HVGWVMDSREHRPRTASISSSPSEGTPTVGSYGCTPQSLPKFQHPSHELLKENGFTQHVY 890
            HVGWVMDSREHRPRTASISSSPSEGTPTVGSYGCTPQSLPKFQHPSHELLKENGFTQHVY
Sbjct: 754  HVGWVMDSREHRPRTASISSSPSEGTPTVGSYGCTPQSLPKFQHPSHELLKENGFTQHVY 813

Query: 891  HKYRRRCLNERKRLGIGQSQEMNTLFRFWSFFLRDHFNKKMYEEFKQLALEDAKEGYRYG 950
            HKYRRRCLNERKRLGIGQSQEMNTLFRFWSFFLRDHFNKKMYEEFKQLALEDAKEGYRYG
Sbjct: 814  HKYRRRCLNERKRLGIGQSQEMNTLFRFWSFFLRDHFNKKMYEEFKQLALEDAKEGYRYG 873

Query: 951  LECLFRYYSYGLEKKFRLDIFKDFQEETVKDYEAGQLYGLEKFWAFLKYSKAKNLDIDPK 1010
            LECLFRYYSYGLEKKFRLDIFKDFQEETVKDYEAGQLYGLEKFWAFLKYSKAKNLDIDPK
Sbjct: 874  LECLFRYYSYGLEKKFRLDIFKDFQEETVKDYEAGQLYGLEKFWAFLKYSKAKNLDIDPK 933

Query: 1011 LQEYLGKFRRLEDFRVDPPMGEEGNHKRHSVVAGGGGGEGRKRCPSQSSSRPAAMISQPP 1070
            LQEYLGKFRRLEDFRVDPPMGEEGNHKRHSVVAGGGGGEGRKRCPSQSSSRPAAMISQPP
Sbjct: 934  LQEYLGKFRRLEDFRVDPPMGEEGNHKRHSVVAGGGGGEGRKRCPSQSSSRPAAMISQPP 993

Query: 1071 TPPTGQPVREDAKWTSQHSNTQTLGK 1096
            TPPTGQPVREDAKWTSQHSNTQTLGK
Sbjct: 994  TPPTGQPVREDAKWTSQHSNTQTLGK 1019


>gi|30061567 La ribonucleoprotein domain family member 2 isoform 1
            [Homo sapiens]
          Length = 914

 Score = 1038 bits (2683), Expect = 0.0
 Identities = 545/938 (58%), Positives = 672/938 (71%), Gaps = 52/938 (5%)

Query: 175  NWPTPGEIAHKSVQPQSHKPQPTRKLPPKKDMKEQ-EKGEGSDSKESPKTKSDESGEEKN 233
            NWPTP E+ +   Q  S   Q  +K   +K+ +E+ EK   SDSKE+ +TK +  GE  +
Sbjct: 3    NWPTPSELVNTGFQ--SVLSQGNKKPQNRKEKEEKVEKRSNSDSKENRETKLNGPGENVS 60

Query: 234  GDEDCQRGGQKKKGNKHKWVPLQIDMKPEVPREKLASRPTRPPEPRHIPANRGEIKGSES 293
             DE  Q   Q+K+ NKHKWVPL +D+     +E+  SR +   +P            +  
Sbjct: 61   EDE-AQSSNQRKRANKHKWVPLHLDVVRSESQERPGSRNSSRCQPE-----------ANK 108

Query: 294  ATYVPVAPPTPAWQPEIKPEPAWHDQDETSSVKSDGAGGARASFRGRGRGRGRGRGRGRG 353
             T+      T +W+ + +      DQD+ SSV+S+G G  R SFRGRGRGRGRGRGRGRG
Sbjct: 109  PTHNNRRNDTRSWKRDREKRD---DQDDVSSVRSEG-GNIRGSFRGRGRGRGRGRGRGRG 164

Query: 354  GTRTHFDYQFGYRKF-DGVEGPRTPKYMNNITYYFDNVSSTELYSVDQELLKDYIKRQIE 412
              R +FDY +GY++  +  + P   +   ++ YY+D+ +  ++Y V++ LLK+YIKRQIE
Sbjct: 165  NPRLNFDYSYGYQEHGERTDQPFQTELNTSMMYYYDDGTGVQVYPVEEALLKEYIKRQIE 224

Query: 413  YYFSVDNLERDFFLRRKMDADGFLPITLIASFHRVQALTTDISLIFAALKDSKVVEIVDE 472
            YYFSV+NLERDFFLR KMD  GFLPI+LIA F RVQALTT+++LI  ALKDS  VEIVDE
Sbjct: 225  YYFSVENLERDFFLRGKMDEQGFLPISLIAGFQRVQALTTNLNLILEALKDSTEVEIVDE 284

Query: 473  KVRRREEPEKWPLP--PIVDYSQTDFSQLLNCPEFVPRQHYQKETESAPGSPRAVTPV-P 529
            K+R++ EPEKWP+P  P      TDFSQL++CPEFVP Q +   TESAP SPR  +P+ P
Sbjct: 285  KMRKKIEPEKWPIPGPPPRSVPPTDFSQLIDCPEFVPGQAFCSHTESAPNSPRIGSPLSP 344

Query: 530  TKTEEVSNLKTLPKGLSASLPDLDSENWIEVKKRPRPSPARPKKSEESRFSHLTSLPQQL 589
             K  E S L+ + +GLS SLPDLDSE WIEVKKR +P+P + ++S         S+P+  
Sbjct: 345  KKNSETSILQAMSRGLSTSLPDLDSEPWIEVKKRHQPAPVKLRES--------VSVPEG- 395

Query: 590  PSQQLMSKDQDEQEELDFLFDEEMEQMDGRKNTFTAWSDEESDYEIDDRDVNKILIVTQT 649
               QL S ++ EQEELDFLFDEE+EQ+ GRKNTFT WSD +SDYEIDD+D+NKILIVTQT
Sbjct: 396  SLNQLCSSEEPEQEELDFLFDEEIEQI-GRKNTFTDWSDNDSDYEIDDQDLNKILIVTQT 454

Query: 650  PHYMRRHPGGDRTGNHTSRAKMSAELAKVINDGLFYYEQDLWAEKFEPEYSQIKQEVENF 709
            P Y+++HPGGDRTG H SRAK+++ELAKVINDGL+YYEQDLW E+ E +++ IKQEVENF
Sbjct: 455  PPYVKKHPGGDRTGTHMSRAKITSELAKVINDGLYYYEQDLWMEEDENKHTAIKQEVENF 514

Query: 710  KKVNMISREQFDTLTPEPPVDPNQEVPPGPPRFQQ--------VP----TDALANKLFGA 757
            KK+N+IS+EQF+ LTPE P +PNQEVP  P + +Q        +P    TD LA KLF  
Sbjct: 515  KKLNLISKEQFENLTPELPFEPNQEVPVAPSQSRQGGVQGVLHIPKKDLTDELAQKLFDV 574

Query: 758  PEPSTIA--RSLPTTVPESPNYRNTRTPRTPRTPQLKDSSQTSRFYPVVKEGRTLDAKMP 815
             E ++ A   SLPT VPESP    TRTP+TPRTP+L+D ++T RFYPVVKE + +D K P
Sbjct: 575  SEITSAAMVHSLPTAVPESPRIHPTRTPKTPRTPRLQDPNKTPRFYPVVKEPKAIDVKSP 634

Query: 816  RKRKTRHSSNPPLESHVGWVMDSREHRPRTASISSS---PSEGTPTVGSYGCTPQSLPKF 872
            RKRKTRHS+NPPLE HVGWVMDSR+  P T+S+S+S   PSEG P  GSYGCTP S PKF
Sbjct: 635  RKRKTRHSTNPPLECHVGWVMDSRDRGPGTSSVSTSNASPSEGAPLAGSYGCTPHSFPKF 694

Query: 873  QHPSHELLKENGFTQHVYHKYRRRCLNERKRLGIGQSQEMNTLFRFWSFFLRDHFNKKMY 932
            QHPSHELLKENGFTQ VYHKYRRRCL+ERKRLGIGQSQEMNTLFRFWSFFLRDHFNKKMY
Sbjct: 695  QHPSHELLKENGFTQQVYHKYRRRCLSERKRLGIGQSQEMNTLFRFWSFFLRDHFNKKMY 754

Query: 933  EEFKQLALEDAKEGYRYGLECLFRYYSYGLEKKFRLDIFKDFQEETVKDYEAGQLYGLEK 992
            EEF+QLA EDAKE YRYGLECLFR+YSYGLEKKFR +IF+DFQEET KDYE+GQLYGLEK
Sbjct: 755  EEFRQLAWEDAKENYRYGLECLFRFYSYGLEKKFRREIFQDFQEETKKDYESGQLYGLEK 814

Query: 993  FWAFLKYSKAKNLDIDPKLQEYLGKFRRLEDFRVDPPMGEEGNHKRHSVVAGGGGGEGRK 1052
            FWA+LKYS++K   IDPKLQEYL  F+RLEDFRVDPP+ +E   KRHS  +  G    R 
Sbjct: 815  FWAYLKYSQSKTQSIDPKLQEYLCSFKRLEDFRVDPPISDEFGRKRHS--STSGEESNRH 872

Query: 1053 RCPSQSSSRPAAMISQPPTPPTGQPVREDAKWTSQHSN 1090
            R P  SS++P        T     P+    +  S  S+
Sbjct: 873  RLPPNSSTKPPNAAKPTSTSELQVPINSPRRNISPESS 910


>gi|30061565 La ribonucleoprotein domain family member 2 isoform 2
           [Homo sapiens]
          Length = 522

 Score =  514 bits (1323), Expect = e-145
 Identities = 280/534 (52%), Positives = 367/534 (68%), Gaps = 33/534 (6%)

Query: 175 NWPTPGEIAHKSVQPQSHKPQPTRKLPPKKDMKEQ-EKGEGSDSKESPKTKSDESGEEKN 233
           NWPTP E+ +   Q  S   Q  +K   +K+ +E+ EK   SDSKE+ +TK +  GE  +
Sbjct: 3   NWPTPSELVNTGFQ--SVLSQGNKKPQNRKEKEEKVEKRSNSDSKENRETKLNGPGENVS 60

Query: 234 GDEDCQRGGQKKKGNKHKWVPLQIDMKPEVPREKLASRPTRPPEPRHIPANRGEIKGSES 293
            DE  Q   Q+K+ NKHKWVPL +D+     +E+  SR +   +P            +  
Sbjct: 61  EDE-AQSSNQRKRANKHKWVPLHLDVVRSESQERPGSRNSSRCQPE-----------ANK 108

Query: 294 ATYVPVAPPTPAWQPEIKPEPAWHDQDETSSVKSDGAGGARASFRGRGRGRGRGRGRGRG 353
            T+      T +W+ + +      DQD+ SSV+S+G G  R SFRGRGRGRGRGRGRGRG
Sbjct: 109 PTHNNRRNDTRSWKRDREKRD---DQDDVSSVRSEG-GNIRGSFRGRGRGRGRGRGRGRG 164

Query: 354 GTRTHFDYQFGYRKF-DGVEGPRTPKYMNNITYYFDNVSSTELYSVDQELLKDYIKRQIE 412
             R +FDY +GY++  +  + P   +   ++ YY+D+ +  ++Y V++ LLK+YIKRQIE
Sbjct: 165 NPRLNFDYSYGYQEHGERTDQPFQTELNTSMMYYYDDGTGVQVYPVEEALLKEYIKRQIE 224

Query: 413 YYFSVDNLERDFFLRRKMDADGFLPITLIASFHRVQALTTDISLIFAALKDSKVVEIVDE 472
           YYFSV+NLERDFFLR KMD  GFLPI+LIA F RVQALTT+++LI  ALKDS  VEIVDE
Sbjct: 225 YYFSVENLERDFFLRGKMDEQGFLPISLIAGFQRVQALTTNLNLILEALKDSTEVEIVDE 284

Query: 473 KVRRREEPEKWPL--PPIVDYSQTDFSQLLNCPEFVPRQHYQKETESAPGSPRAVTPV-P 529
           K+R++ EPEKWP+  PP      TDFSQL++CPEFVP Q +   TESAP SPR  +P+ P
Sbjct: 285 KMRKKIEPEKWPIPGPPPRSVPPTDFSQLIDCPEFVPGQAFCSHTESAPNSPRIGSPLSP 344

Query: 530 TKTEEVSNLKTLPKGLSASLPDLDSENWIEVKKRPRPSPARPKKSEESRFSHLTSLPQQL 589
            K  E S L+ + +GLS SLPDLDSE WIEVKKR +P+P + ++S         S+P+  
Sbjct: 345 KKNSETSILQAMSRGLSTSLPDLDSEPWIEVKKRHQPAPVKLRES--------VSVPEG- 395

Query: 590 PSQQLMSKDQDEQEELDFLFDEEMEQMDGRKNTFTAWSDEESDYEIDDRDVNKILIVTQT 649
              QL S ++ EQEELDFLFDEE+EQ+ GRKNTFT WSD +SDYEIDD+D+NKILIVTQT
Sbjct: 396 SLNQLCSSEEPEQEELDFLFDEEIEQI-GRKNTFTDWSDNDSDYEIDDQDLNKILIVTQT 454

Query: 650 PHYMRRHPGGDRTGNHTSRAKMSAELAKVINDGLFYYEQDLWAEKFEPEYSQIK 703
           P Y+++HPGGDRTG H SRAK+++ELAKVINDGL+YYEQDLW E+ E +++ IK
Sbjct: 455 PPYVKKHPGGDRTGTHMSRAKITSELAKVINDGLYYYEQDLWMEEDENKHTAIK 508


>gi|30061569 La ribonucleoprotein domain family member 2 isoform 3
           [Homo sapiens]
          Length = 358

 Score =  293 bits (749), Expect = 8e-79
 Identities = 164/345 (47%), Positives = 221/345 (64%), Gaps = 22/345 (6%)

Query: 175 NWPTPGEIAHKSVQPQSHKPQPTRKLPPKKDMKEQ-EKGEGSDSKESPKTKSDESGEEKN 233
           NWPTP E+ +   Q  S   Q  +K   +K+ +E+ EK   SDSKE+ +TK +  GE  +
Sbjct: 3   NWPTPSELVNTGFQ--SVLSQGNKKPQNRKEKEEKVEKRSNSDSKENRETKLNGPGENVS 60

Query: 234 GDEDCQRGGQKKKGNKHKWVPLQIDMKPEVPREKLASRPTRPPEPRHIPANRGEIKGSES 293
            DE  Q   Q+K+ NKHKWVPL +D+     +E+  SR +   +P            +  
Sbjct: 61  EDE-AQSSNQRKRANKHKWVPLHLDVVRSESQERPGSRNSSRCQPE-----------ANK 108

Query: 294 ATYVPVAPPTPAWQPEIKPEPAWHDQDETSSVKSDGAGGARASFRGRGRGRGRGRGRGRG 353
            T+      T +W+ + +      DQD+ SSV+S+G G  R SFRGRGRGRGRGRGRGRG
Sbjct: 109 PTHNNRRNDTRSWKRDREKRD---DQDDVSSVRSEG-GNIRGSFRGRGRGRGRGRGRGRG 164

Query: 354 GTRTHFDYQFGYRKF-DGVEGPRTPKYMNNITYYFDNVSSTELYSVDQELLKDYIKRQIE 412
             R +FDY +GY++  +  + P   +   ++ YY+D+ +  ++Y V++ LLK+YIKRQIE
Sbjct: 165 NPRLNFDYSYGYQEHGERTDQPFQTELNTSMMYYYDDGTGVQVYPVEEALLKEYIKRQIE 224

Query: 413 YYFSVDNLERDFFLRRKMDADGFLPITLIASFHRVQALTTDISLIFAALKDSKVVEIVDE 472
           YYFSV+NLERDFFLR KMD  GFLPI+LIA F RVQALTT+++LI  ALKDS  VEIVDE
Sbjct: 225 YYFSVENLERDFFLRGKMDEQGFLPISLIAGFQRVQALTTNLNLILEALKDSTEVEIVDE 284

Query: 473 KVRRREEPEKWPL--PPIVDYSQTDFSQLLNCPEFVPRQHYQKET 515
           K+R++ EPEKWP+  PP      TDFSQL++CPEFVP Q +   T
Sbjct: 285 KMRKKIEPEKWPIPGPPPRSVPPTDFSQLIDCPEFVPGQAFCSHT 329


>gi|239753842 PREDICTED: similar to hCG2040199 [Homo sapiens]
          Length = 315

 Score =  100 bits (248), Expect = 1e-20
 Identities = 54/116 (46%), Positives = 78/116 (67%), Gaps = 2/116 (1%)

Query: 364 GYRKFDGVEGPRTPKYMNNITYYFDNVSSTELYSVDQELLKDYIKRQIEYYFSVDNLERD 423
           G +K    +  R  +   ++ YY+D+ +  ++Y V++ LLK+ IKRQIE+YF+ +N ERD
Sbjct: 182 GNKKPQDRKEKRREELNTSMMYYYDDGTGVQVYRVEEALLKECIKRQIEHYFNAENSERD 241

Query: 424 FFLRRKMDADGFLPITLIASFHRVQALTTDISLIFAALKDSKVVEIVDEKVRRREE 479
           +FLR K      LPI LIA F RVQALTT  +LI  ALKDS  VEI++EK+R++ +
Sbjct: 242 YFLRGKRGEQDSLPIFLIAGFQRVQALTT--NLITEALKDSTEVEIMNEKMRKKNQ 295



 Score = 50.8 bits (120), Expect = 7e-06
 Identities = 51/190 (26%), Positives = 74/190 (38%), Gaps = 14/190 (7%)

Query: 31  PAPEGKGEPGPNDVRGGEPDGSARRPRPPCAKPHKEGTGQ--QERESPRPLQLPGAEGPA 88
           PA   +G   P  V        AR  RP   +P  E  G+     E  +     GA G  
Sbjct: 8   PAASHRGLEDPPAVTAERESLLARVNRPAEHQPLAEHEGKVAAREEKAKATTSEGARGEP 67

Query: 89  ISDGEEGGGEPGAG-GGAAGAAGAGRRDFVEAPP--PKVNPWTKNALPPVLTTVNGQSPP 145
            S        P A        A AG ++  + P   PK NPW K     +  T  G+  P
Sbjct: 68  SSLVVPTRSMPQAAVPDTMEEAAAGPKEKRQPPLLLPKGNPWNKKPSQHLSPTTTGRPQP 127

Query: 146 E------HSAPAKVVRAAVPKQRKGSKVGDFGDAINWPTPGEI---AHKSVQPQSHKPQP 196
                       K+++A   K++K +K  DF D  NW TP E+    ++SV  Q +K   
Sbjct: 128 ALETLEAEFGSLKIMKAGKLKKKKSNKASDFKDMENWRTPSELVNTGYQSVLSQGNKKPQ 187

Query: 197 TRKLPPKKDM 206
            RK   ++++
Sbjct: 188 DRKEKRREEL 197


>gi|169166778 PREDICTED: similar to hCG2040199 [Homo sapiens]
          Length = 315

 Score =  100 bits (248), Expect = 1e-20
 Identities = 54/116 (46%), Positives = 78/116 (67%), Gaps = 2/116 (1%)

Query: 364 GYRKFDGVEGPRTPKYMNNITYYFDNVSSTELYSVDQELLKDYIKRQIEYYFSVDNLERD 423
           G +K    +  R  +   ++ YY+D+ +  ++Y V++ LLK+ IKRQIE+YF+ +N ERD
Sbjct: 182 GNKKPQDRKEKRREELNTSMMYYYDDGTGVQVYRVEEALLKECIKRQIEHYFNAENSERD 241

Query: 424 FFLRRKMDADGFLPITLIASFHRVQALTTDISLIFAALKDSKVVEIVDEKVRRREE 479
           +FLR K      LPI LIA F RVQALTT  +LI  ALKDS  VEI++EK+R++ +
Sbjct: 242 YFLRGKRGEQDSLPIFLIAGFQRVQALTT--NLITEALKDSTEVEIMNEKMRKKNQ 295



 Score = 50.8 bits (120), Expect = 7e-06
 Identities = 51/190 (26%), Positives = 74/190 (38%), Gaps = 14/190 (7%)

Query: 31  PAPEGKGEPGPNDVRGGEPDGSARRPRPPCAKPHKEGTGQ--QERESPRPLQLPGAEGPA 88
           PA   +G   P  V        AR  RP   +P  E  G+     E  +     GA G  
Sbjct: 8   PAASHRGLEDPPAVTAERESLLARVNRPAEHQPLAEHEGKVAAREEKAKATTSEGARGEP 67

Query: 89  ISDGEEGGGEPGAG-GGAAGAAGAGRRDFVEAPP--PKVNPWTKNALPPVLTTVNGQSPP 145
            S        P A        A AG ++  + P   PK NPW K     +  T  G+  P
Sbjct: 68  SSLVVPTRSMPQAAVPDTMEEAAAGPKEKRQPPLLLPKGNPWNKKPSQHLSPTTTGRPQP 127

Query: 146 E------HSAPAKVVRAAVPKQRKGSKVGDFGDAINWPTPGEI---AHKSVQPQSHKPQP 196
                       K+++A   K++K +K  DF D  NW TP E+    ++SV  Q +K   
Sbjct: 128 ALETLEAEFGSLKIMKAGKLKKKKSNKASDFKDMENWRTPSELVNTGYQSVLSQGNKKPQ 187

Query: 197 TRKLPPKKDM 206
            RK   ++++
Sbjct: 188 DRKEKRREEL 197


>gi|169166363 PREDICTED: similar to hCG2040199 [Homo sapiens]
          Length = 315

 Score =  100 bits (248), Expect = 1e-20
 Identities = 54/116 (46%), Positives = 78/116 (67%), Gaps = 2/116 (1%)

Query: 364 GYRKFDGVEGPRTPKYMNNITYYFDNVSSTELYSVDQELLKDYIKRQIEYYFSVDNLERD 423
           G +K    +  R  +   ++ YY+D+ +  ++Y V++ LLK+ IKRQIE+YF+ +N ERD
Sbjct: 182 GNKKPQDRKEKRREELNTSMMYYYDDGTGVQVYRVEEALLKECIKRQIEHYFNAENSERD 241

Query: 424 FFLRRKMDADGFLPITLIASFHRVQALTTDISLIFAALKDSKVVEIVDEKVRRREE 479
           +FLR K      LPI LIA F RVQALTT  +LI  ALKDS  VEI++EK+R++ +
Sbjct: 242 YFLRGKRGEQDSLPIFLIAGFQRVQALTT--NLITEALKDSTEVEIMNEKMRKKNQ 295



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 51/190 (26%), Positives = 74/190 (38%), Gaps = 14/190 (7%)

Query: 31  PAPEGKGEPGPNDVRGGEPDGSARRPRPPCAKPHKEGTGQ--QERESPRPLQLPGAEGPA 88
           PA   +G   P  V        AR  RP   +P  E  G+     E  +     GA G  
Sbjct: 8   PAASHRGLEDPPAVTAERESLLARVNRPAEHQPLAEHEGKVAAREEKAKATTSEGARGEP 67

Query: 89  ISDGEEGGGEPG-AGGGAAGAAGAGRRDFVEAPP--PKVNPWTKNALPPVLTTVNGQSPP 145
            S        P  A       A AG ++  + P   PK NPW K     +  T  G+  P
Sbjct: 68  SSLVVPTRSMPQVAVPDTMEEAAAGPKEKRQPPLLLPKGNPWNKKPSQHLSPTTTGRPQP 127

Query: 146 E------HSAPAKVVRAAVPKQRKGSKVGDFGDAINWPTPGEI---AHKSVQPQSHKPQP 196
                       K+++A   K++K +K  DF D  NW TP E+    ++SV  Q +K   
Sbjct: 128 ALETLEAEFGSLKIMKAGKLKKKKSNKASDFKDMENWRTPSELVNTGYQSVLSQGNKKPQ 187

Query: 197 TRKLPPKKDM 206
            RK   ++++
Sbjct: 188 DRKEKRREEL 197


>gi|40353738 c-Mpl binding protein isoform a [Homo sapiens]
          Length = 724

 Score = 73.6 bits (179), Expect = 1e-12
 Identities = 44/136 (32%), Positives = 76/136 (55%), Gaps = 16/136 (11%)

Query: 382 NITYYFDNVSSTELYSVDQELLKDYIKRQIEYYFSVDNLERDFFLRRKMDADGFLPITLI 441
           +++Y   +VS     +V  E LK+ +K+Q+E+ FS +NL +D +L  +MD+D F+PI  +
Sbjct: 98  DLSYQIYDVSGESNSAVSTEDLKECLKKQLEFCFSRENLSKDLYLISQMDSDQFIPIWTV 157

Query: 442 ASFHRVQALTTDISLIFAALKDSKVVEIVD--EKVR---------RREEPEKWPLPPIVD 490
           A+   ++ LTTD  LI   L+ S +V++ +  EKVR          RE PE  P+  +  
Sbjct: 158 ANMEEIKKLTTDPDLILEVLRSSPMVQVDEKGEKVRPSHKRCIVILREIPETTPIEEVKG 217

Query: 491 YSQTDFSQLLNCPEFV 506
             +++     NCP+ +
Sbjct: 218 LFKSE-----NCPKVI 228


>gi|40353736 c-Mpl binding protein isoform c [Homo sapiens]
          Length = 653

 Score = 73.6 bits (179), Expect = 1e-12
 Identities = 44/136 (32%), Positives = 76/136 (55%), Gaps = 16/136 (11%)

Query: 382 NITYYFDNVSSTELYSVDQELLKDYIKRQIEYYFSVDNLERDFFLRRKMDADGFLPITLI 441
           +++Y   +VS     +V  E LK+ +K+Q+E+ FS +NL +D +L  +MD+D F+PI  +
Sbjct: 98  DLSYQIYDVSGESNSAVSTEDLKECLKKQLEFCFSRENLSKDLYLISQMDSDQFIPIWTV 157

Query: 442 ASFHRVQALTTDISLIFAALKDSKVVEIVD--EKVR---------RREEPEKWPLPPIVD 490
           A+   ++ LTTD  LI   L+ S +V++ +  EKVR          RE PE  P+  +  
Sbjct: 158 ANMEEIKKLTTDPDLILEVLRSSPMVQVDEKGEKVRPSHKRCIVILREIPETTPIEEVKG 217

Query: 491 YSQTDFSQLLNCPEFV 506
             +++     NCP+ +
Sbjct: 218 LFKSE-----NCPKVI 228


>gi|40353740 c-Mpl binding protein isoform b [Homo sapiens]
          Length = 730

 Score = 73.6 bits (179), Expect = 1e-12
 Identities = 44/136 (32%), Positives = 76/136 (55%), Gaps = 16/136 (11%)

Query: 382 NITYYFDNVSSTELYSVDQELLKDYIKRQIEYYFSVDNLERDFFLRRKMDADGFLPITLI 441
           +++Y   +VS     +V  E LK+ +K+Q+E+ FS +NL +D +L  +MD+D F+PI  +
Sbjct: 104 DLSYQIYDVSGESNSAVSTEDLKECLKKQLEFCFSRENLSKDLYLISQMDSDQFIPIWTV 163

Query: 442 ASFHRVQALTTDISLIFAALKDSKVVEIVD--EKVR---------RREEPEKWPLPPIVD 490
           A+   ++ LTTD  LI   L+ S +V++ +  EKVR          RE PE  P+  +  
Sbjct: 164 ANMEEIKKLTTDPDLILEVLRSSPMVQVDEKGEKVRPSHKRCIVILREIPETTPIEEVKG 223

Query: 491 YSQTDFSQLLNCPEFV 506
             +++     NCP+ +
Sbjct: 224 LFKSE-----NCPKVI 234


>gi|10835067 autoantigen La [Homo sapiens]
          Length = 408

 Score = 66.6 bits (161), Expect = 1e-10
 Identities = 39/96 (40%), Positives = 59/96 (61%), Gaps = 4/96 (4%)

Query: 403 LKDYIKRQIEYYFSVDNLERDFFLRRKMDAD-GFLPITLIASFHRVQALTTDISLIFAAL 461
           L+  I  QIEYYF   NL RD FL+ ++  D G++P+ ++  F+R+  LTTD ++I  AL
Sbjct: 13  LEAKICHQIEYYFGDFNLPRDKFLKEQIKLDEGWVPLEIMIKFNRLNRLTTDFNVIVEAL 72

Query: 462 KDSK--VVEIVDEKVRRREEPEKWPLPPIVDYSQTD 495
             SK  ++EI ++K + R  P K PLP + D  + D
Sbjct: 73  SKSKAELMEISEDKTKIRRSPSK-PLPEVTDEYKND 107


>gi|109809739 La ribonucleoprotein domain family, member 7 [Homo
           sapiens]
          Length = 582

 Score = 58.2 bits (139), Expect = 4e-08
 Identities = 34/84 (40%), Positives = 58/84 (69%), Gaps = 4/84 (4%)

Query: 400 QELLKDYIKRQIEYYFSVDNLERDFFLRRKMDA--DGFLPITLIASFHRVQALTTDISLI 457
           +++L D I +Q++++F   NL +D FLR +++   DG++ I+L+ SF++++ LTTD  LI
Sbjct: 32  KQVLAD-IAKQVDFWFGDANLHKDRFLREQIEKSRDGYVDISLLVSFNKMKKLTTDGKLI 90

Query: 458 FAALKDSKVVEIVDEKVR-RREEP 480
             AL+ S VVE+  E  R RR++P
Sbjct: 91  ARALRSSAVVELDLEGTRIRRKKP 114


>gi|109809741 La ribonucleoprotein domain family, member 7 [Homo
           sapiens]
          Length = 582

 Score = 58.2 bits (139), Expect = 4e-08
 Identities = 34/84 (40%), Positives = 58/84 (69%), Gaps = 4/84 (4%)

Query: 400 QELLKDYIKRQIEYYFSVDNLERDFFLRRKMDA--DGFLPITLIASFHRVQALTTDISLI 457
           +++L D I +Q++++F   NL +D FLR +++   DG++ I+L+ SF++++ LTTD  LI
Sbjct: 32  KQVLAD-IAKQVDFWFGDANLHKDRFLREQIEKSRDGYVDISLLVSFNKMKKLTTDGKLI 90

Query: 458 FAALKDSKVVEIVDEKVR-RREEP 480
             AL+ S VVE+  E  R RR++P
Sbjct: 91  ARALRSSAVVELDLEGTRIRRKKP 114


>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
           preproprotein [Homo sapiens]
          Length = 331

 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 81/312 (25%), Positives = 112/312 (35%), Gaps = 53/312 (16%)

Query: 19  EEHGGLVRKKPP-PAPEG----KGEPGPNDVRGGEPDGSARRPR--PPCAKPHKEGTGQQ 71
           EE   L+   P  P+P+G    +G P P     G P     +P+  PP  KP  +G   Q
Sbjct: 26  EESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKP--QGPPPQ 83

Query: 72  ERESPRPLQLPG-AEGPAISDGEEGGGEPGAGGGAAGAAGAGRRDFVEAPPPKVNPWTKN 130
             +S  P   PG  +GP    G +  G P   G   G    G  +  + PPP   P    
Sbjct: 84  GDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG-GNRPQGPPPPGKP---- 138

Query: 131 ALPPVLTTVNGQSPPEHSAPAKVVRAAVPKQRKGSKVGDFGDAINWPTPGEIAHKSVQPQ 190
                      Q PP     ++  R+   K +     G  G+    P P     +   PQ
Sbjct: 139 -----------QGPPPQGDKSRSPRSPPGKPQGPPPQG--GNQPQGPPPPPGKPQGPPPQ 185

Query: 191 SHKPQPTRKLPPKKDMKEQEKGEGSDSKESPKTKSDESGEEKNGDEDCQRGGQKKKGNKH 250
             K +P    PP K      +G+ S S +SP  K                 G   +G   
Sbjct: 186 GGK-KPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQ---------------GPPPQGGNQ 229

Query: 251 KWVPLQIDMKPEVPREKLASRPTRPP---EPRHIPANRGEIKGSESATYVPVAPPTPAWQ 307
              P     KP+ P  +  ++P  PP   +P+  PA  G    S+SA   P  P  P  Q
Sbjct: 230 PQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGG--SKSQSARSPPGKPQGPPQQ 287

Query: 308 ----PEIKPEPA 315
               P+  P PA
Sbjct: 288 EGNNPQGPPPPA 299



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 65/265 (24%), Positives = 92/265 (34%), Gaps = 48/265 (18%)

Query: 27  KKPPPAPEGKGEPGPNDVRG---------GEPDGSARRPR--PPCAKPHKEGTGQQERES 75
           + PP  P+G    G N  +G         G P     RP+  PP  KP  +G   Q  +S
Sbjct: 91  RSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKP--QGPPPQGDKS 148

Query: 76  PRPLQLPG-AEGPAISDGEEGGGEPGAGGGAAGAAGAGRRDFVEAPPPKVNPWTKNALPP 134
             P   PG  +GP    G +  G P   G   G    G +   + PPP   P        
Sbjct: 149 RSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKK-PQGPPPPGKP-------- 199

Query: 135 VLTTVNGQSPPEHSAPAKVVRAAVPKQRKGSKVGDFGDAINWPTPGEIAHKSVQPQ-SHK 193
                  Q PP     ++  ++   K +     G  G+    P P     +   PQ  +K
Sbjct: 200 -------QGPPPQGDKSRSSQSPPGKPQGPPPQG--GNQPQGPPPPPGKPQGPPPQGGNK 250

Query: 194 PQPTRKLPPKKDMKEQEKGEGSDSKESPKTKSDESGEEKNGDEDCQRGGQKKKGNKHKWV 253
           PQ     P K      + G  S S  SP  K               +G  +++GN  +  
Sbjct: 251 PQGPPP-PGKPQGPPAQGGSKSQSARSPPGK--------------PQGPPQQEGNNPQGP 295

Query: 254 PLQIDMKPEVPREKLASRPTRPPEP 278
           P      P+ P+   A +P  PP P
Sbjct: 296 PPPAGGNPQQPQAPPAGQPQGPPRP 320



 Score = 31.6 bits (70), Expect = 4.3
 Identities = 31/145 (21%), Positives = 45/145 (31%), Gaps = 2/145 (1%)

Query: 10  PGGATLLQAEEHGGLVRKKPPPAPEGKGEPGPNDVRGGEPDGSARRPRPPCAKPHK-EGT 68
           P G    Q     G  +  PP   + +    P     G P     +P+ P   P K +G 
Sbjct: 184 PQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP 243

Query: 69  GQQERESPRPLQLPG-AEGPAISDGEEGGGEPGAGGGAAGAAGAGRRDFVEAPPPKVNPW 127
             Q    P+    PG  +GP    G +        G   G       +    PPP     
Sbjct: 244 PPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNP 303

Query: 128 TKNALPPVLTTVNGQSPPEHSAPAK 152
            +   PP         PP+   P++
Sbjct: 304 QQPQAPPAGQPQGPPRPPQGGRPSR 328


>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
           sapiens]
          Length = 309

 Score = 55.5 bits (132), Expect = 3e-07
 Identities = 77/294 (26%), Positives = 103/294 (35%), Gaps = 65/294 (22%)

Query: 22  GGLVRKKPPPAPEGKGEPGPNDVRGGEPDGSARRPRPPCAKPHKEGTGQQERESPRPLQL 81
           GG   + PPP P GK E GP    G +  G   RP  P  +P  +G  Q +   PRP + 
Sbjct: 64  GGNQSQGPPPRP-GKPE-GPPPQGGNQSQGPPPRPGKPEGQP-PQGGNQSQGPPPRPGK- 119

Query: 82  PGAEGPAISDGEEGGGEPGAGGGAAGAAGAGRRDFVEAPPPKVNPWTKNALPPVLTTVNG 141
              EGP    G +  G P   G   G    G     + PPP+     K   PP       
Sbjct: 120 --PEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQS-QGPPPRPG---KPEGPPPQGGNQS 173

Query: 142 QSPPEHSAPAKVVRAAVPKQRKGSKVGDFGDAINWPTPGEIAHKSVQPQSHKPQPTRKLP 201
           Q PP H           P + +G            P  G    +   P+  KP+     P
Sbjct: 174 QGPPPH-----------PGKPEGP-----------PPQGGNQSQGPPPRPGKPEG----P 207

Query: 202 PKKDMKEQEKGEGSDSKESPKTKSDESGEEKNGDEDCQRGGQKKKGNKHKWVPLQIDMKP 261
           P +         G+ S+  P       G          +GG K +G      P     KP
Sbjct: 208 PPQG--------GNQSQGPPPRPGKPEGPPS-------QGGNKPQG------PPPHPGKP 246

Query: 262 EVPREKLASRPTRPPEPRHIPANRGEIKGSESATYVPVAP-PTPAWQPEIKPEP 314
           + P  +  ++P RPP P       G  +G       P  P P PA +P+  P P
Sbjct: 247 QGPPPQEGNKPQRPPPP-------GRPQGPPPPGGNPQQPLPPPAGKPQGPPPP 293



 Score = 34.7 bits (78), Expect = 0.51
 Identities = 29/89 (32%), Positives = 34/89 (38%), Gaps = 9/89 (10%)

Query: 22  GGLVRKKPPPAPEGKGEPGPNDVRGGEPDGSARRPRPPCAKPHKEGTGQQERESPRPLQL 81
           GG   + PPP P GK E GP    G +P G    P  P   P +EG   Q    P   Q 
Sbjct: 211 GGNQSQGPPPRP-GKPE-GPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPPPGRPQG 268

Query: 82  PGAEG-------PAISDGEEGGGEPGAGG 103
           P   G       P  +   +G   P  GG
Sbjct: 269 PPPPGGNPQQPLPPPAGKPQGPPPPPQGG 297


>gi|57634536 La ribonucleoprotein domain family, member 4B [Homo
           sapiens]
          Length = 738

 Score = 55.1 bits (131), Expect = 4e-07
 Identities = 27/74 (36%), Positives = 48/74 (64%), Gaps = 1/74 (1%)

Query: 400 QELLKDYIKRQIEYYFSVDNLERDFFLRRKMDADGFLPITLIASFHRVQALTTDISLIFA 459
           QE  ++ +K+ +E+  S +NL  D +L  +MD+D ++PIT +A+   ++ L+TD+ LI  
Sbjct: 153 QEDPREVLKKTLEFCLSRENLASDMYLISQMDSDQYVPITTVANLDHIKKLSTDVDLIVE 212

Query: 460 ALKDSKVVEIVDEK 473
            L+   +V+ VDEK
Sbjct: 213 VLRSLPLVQ-VDEK 225


>gi|37537710 La ribonucleoprotein domain family, member 6 isoform 1
           [Homo sapiens]
          Length = 491

 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 34/82 (41%), Positives = 53/82 (64%), Gaps = 5/82 (6%)

Query: 399 DQELLKDYIKRQIEYYFSVDNLERDFFLRRKMDAD--GFLPITLIASFHRVQALTTDISL 456
           D+EL+K  +  QIE+YFS +NLE+D FL + +  +  G++ + L+ SF +V+ LT D   
Sbjct: 89  DEELIKKLVD-QIEFYFSDENLEKDAFLLKHVRRNKLGYVSVKLLTSFKKVKHLTRDWRT 147

Query: 457 IFAALKDSKVVEIVDE--KVRR 476
              ALK S V+E+ ++  KVRR
Sbjct: 148 TAHALKYSVVLELNEDHRKVRR 169


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 84/316 (26%), Positives = 102/316 (32%), Gaps = 54/316 (17%)

Query: 9   LPGGATLLQAEEHGGLVRKKPPPAPEGK----GEPGPNDVRGGEPDGSARRPRPPCAKPH 64
           LPG   L  +    G   K  PP P G+    G PGP   RG         P+    +P 
Sbjct: 534 LPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPG 593

Query: 65  KEGTGQQERESPRPLQLPGAEGPAISDGEEGGGEPGAGGGAAGAAG----AGRRDFVEAP 120
           K G    ER  P P   PGA GPA  DGE G   P    G AG  G    AG   F   P
Sbjct: 594 KAG----ERGVPGP---PGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLP 646

Query: 121 PPKVNPWTKNALPPVLTTVNGQSPPEHSAPAKVVRAAVPKQRKGSKVGDFGDAINWPTPG 180
            P        A PP         P E   P   + A  P   +G +            PG
Sbjct: 647 GP--------AGPP----GEAGKPGEQGVPGD-LGAPGPSGARGER----------GFPG 683

Query: 181 EIAHKSVQ--PQSHKPQPTRKLPPKKDMKEQEKGEGSDSKESPKTKSDESGEEKNGDEDC 238
           E   + VQ  P    P+     P     K      G+   +         GE        
Sbjct: 684 E---RGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERG------ 734

Query: 239 QRGGQKKKGNKHKWVPLQIDMKPEVPREKLASRPTRPPEPRHIPANRGEIKGSESATYVP 298
             G    KG++    P   D  P     +  + P  PP P   P ++G     ES    P
Sbjct: 735 AAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKG-----ESGPSGP 789

Query: 299 VAPPTPAWQPEIKPEP 314
             P      P  + EP
Sbjct: 790 AGPTGARGAPGDRGEP 805



 Score = 50.4 bits (119), Expect = 9e-06
 Identities = 92/380 (24%), Positives = 123/380 (32%), Gaps = 46/380 (12%)

Query: 23   GLVRKKPPPAPEG----KGEPGPNDVRGGEPDGSARRPRPPCAKPHKEGTGQQERESPRP 78
            GL     PP P G    KGE GP+   G  P G+   P               +R  P P
Sbjct: 764  GLTGPIGPPGPAGAPGDKGESGPSGPAG--PTGARGAPG--------------DRGEPGP 807

Query: 79   LQLPGAEGPAISDGEEGG-GEPGAGGGAAGAAGAGRRDFVEAPPPKVN---PWTKNAL-- 132
                G  GP  +DG+ G  GEPG  G    A   G       P P  N   P  K A   
Sbjct: 808  PGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGS 867

Query: 133  --PPVLTTVNGQS----PPEHSAPAKVVRAAVPKQRKGSKVGDFGDAINWPTPGEI---- 182
              PP  T   G +    PP  S  A       P  ++G K G  G+      PGE+    
Sbjct: 868  AGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGK-GPRGETGPAGRPGEVGPPG 926

Query: 183  ----AHKSVQPQSHKPQPTRKLPPKKDMKEQEKGEGSDSKESPKTKSDESGEEKNGDEDC 238
                A +   P +  P      P  + +  Q    G   +   +      G      +  
Sbjct: 927  PPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQG 986

Query: 239  QRGGQKKKGNKHKWVPLQIDMKPEVPREKLASRPTRPPEPRHIPANRGEIKGSESATYVP 298
              G   ++G      P  +   P     + A      P     P  +G+ +G       P
Sbjct: 987  PSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGD-RGETGPAGPP 1045

Query: 299  VAPPTPAWQPEIKPEPAWHDQDETSSVKSDGAGGARASFRGRGRGRGRGRGRGRGGTRTH 358
             AP  P     + P     D+ ET      G  G       RG    +G    +G T   
Sbjct: 1046 GAPGAPGAPGPVGPAGKSGDRGETGPA---GPAGPVGPVGARGPAGPQGPRGDKGETGEQ 1102

Query: 359  FDYQF-GYRKFDGVEGPRTP 377
             D    G+R F G++GP  P
Sbjct: 1103 GDRGIKGHRGFSGLQGPPGP 1122



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 80/323 (24%), Positives = 101/323 (31%), Gaps = 73/323 (22%)

Query: 23   GLVRKKPPPAPEGK-------------GEPGPNDVRG-----GEPDGSARRPRP----PC 60
            G V    PP P G+             G PGP  + G     G P     R  P    P 
Sbjct: 920  GEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPS 979

Query: 61   AKPHKEGTG--QQERESPRPLQLPGAEGPAISDGEEGG----------GEPGAGG--GAA 106
             +P K+G      ER  P P+  PG  GP    G EG           G PGA G  G  
Sbjct: 980  GEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGET 1039

Query: 107  GAAGAGRRDFVEAPPPKVNPWTKNALPPVLTTVNGQSPPEHSA-PAKVVRAAVPKQRKGS 165
            G AG          P  V P  K+          G++ P   A P   V A  P   +G 
Sbjct: 1040 GPAGPPGAPGAPGAPGPVGPAGKSG-------DRGETGPAGPAGPVGPVGARGPAGPQGP 1092

Query: 166  KVGDFGDAINWPTPGEIAHKSVQPQSHKPQPTRKLPPKKDMKEQEKGEGSDSKESPKTKS 225
            + GD G+       G   H+        P P                 GS  ++ P   S
Sbjct: 1093 R-GDKGETGEQGDRGIKGHRGFSGLQGPPGP----------------PGSPGEQGPSGAS 1135

Query: 226  DESGEEKNGDEDCQRG--GQKKKGNKHKWVPLQIDMKPEVPREKLA-SRPTRPPEPRHIP 282
              +G          RG  G      K     L   + P  PR +   + P  PP P   P
Sbjct: 1136 GPAG---------PRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPP 1186

Query: 283  ANRGEIKGSESATYVPVAPPTPA 305
               G        +++P  P   A
Sbjct: 1187 GPPGPPSAGFDFSFLPQPPQEKA 1209



 Score = 39.7 bits (91), Expect = 0.016
 Identities = 93/371 (25%), Positives = 121/371 (32%), Gaps = 77/371 (20%)

Query: 29  PPPAPEGKGEPGPNDVRGGEPDGSARR-PRPPCAKPHKEGTGQQERESPRPLQLPGAEGP 87
           PP AP  +G  GP     GEP  S    PR P   P K G    + E+ +P + PG  GP
Sbjct: 192 PPGAPGPQGFQGPPG-EPGEPGASGPMGPRGPPGPPGKNG---DDGEAGKPGR-PGERGP 246

Query: 88  AISDGEEG----GGEPGAGGGAAGAAGAGRRDFVEAPPPKVNPWTKNALPPVLTTVNGQS 143
               G  G     G PG  G    +   G +       PK  P                S
Sbjct: 247 PGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEP---------------GS 291

Query: 144 PPEHSAPAKVVRAAVPKQRKGSKVGDFGDAINWPTPGEIAHKSVQPQSHKPQPTRKLPP- 202
           P E+ AP ++    +P +R   + G  G A      G   +      +  P PT    P 
Sbjct: 292 PGENGAPGQMGPRGLPGER--GRPGAPGPA------GARGNDGATGAAGPPGPTGPAGPP 343

Query: 203 -------------KKDMKEQEKGEGSDSKESPKTKSDESGEEKNGDEDCQRGGQKKKGNK 249
                         +  +  E  +G   +  P   +  +G   N   D Q G +   G  
Sbjct: 344 GFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAP 403

Query: 250 HKWVPLQIDMKPEVPREKLASRPTRPPEPRHIPANRGE--IKGSESATYVPVAP-PTPAW 306
                  I   P  P  +  S P  P  P     N GE    GS+  T     P P    
Sbjct: 404 ------GIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQ 457

Query: 307 QPEIKPEPAWHDQDETSSVKSDGAGGARASFRGRGRGRGRGRGRGRGGTRTHFDYQFGYR 366
            P   P PA            +G  GAR      G     G  RG  G+R       G+ 
Sbjct: 458 GP---PGPA----------GEEGKRGARGEPGPTGLPGPPGE-RGGPGSR-------GFP 496

Query: 367 KFDGVEGPRTP 377
             DGV GP+ P
Sbjct: 497 GADGVAGPKGP 507



 Score = 39.3 bits (90), Expect = 0.021
 Identities = 81/323 (25%), Positives = 104/323 (32%), Gaps = 66/323 (20%)

Query: 30  PPAPEG----------------KGEPGPNDVRG-----GEPDGSARRPRP-PCAKPHKEG 67
           PP P+G                KGEPGP  V+G     GE      R  P P   P   G
Sbjct: 426 PPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPG 485

Query: 68  TGQQERESPRPLQLPGAEGPAISDGEEG-GGEPGAGG--------GAAGAAGAGRRDFVE 118
               ER  P     PGA+G A   G  G  G PG  G        G  G AG      + 
Sbjct: 486 ----ERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLT 541

Query: 119 APPPKVNPWTKNALPPVLTTVNGQ----SPPEHSAPAKVVRAAVPKQRKG--SKVGDFGD 172
             P    P  K   PP     +G+     PP     A V+    PK   G   K G+ G 
Sbjct: 542 GSPGSPGPDGKTG-PPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERG- 599

Query: 173 AINWPTPGEIAHKSVQPQSHKPQPTRKLPPKKDMKEQEKG-----EGSDSKESPKTKSDE 227
            +  P PG +       ++    P     P  +  EQ        +G      P  ++ +
Sbjct: 600 -VPGP-PGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGK 657

Query: 228 SGEEKNGDEDCQRGGQKKKGNKHKWVPLQIDMKPEVPREKLASRPTRPPEPR---HIPAN 284
            GE+    +    G    +G +              P E+    P  P  PR     P N
Sbjct: 658 PGEQGVPGDLGAPGPSGARGER------------GFPGERGVQGPPGPAGPRGANGAPGN 705

Query: 285 RGEIKGSESATYVPVAPPTPAWQ 307
            G  KG   A   P +   P  Q
Sbjct: 706 DG-AKGDAGAPGAPGSQGAPGLQ 727



 Score = 38.9 bits (89), Expect = 0.027
 Identities = 37/105 (35%), Positives = 44/105 (41%), Gaps = 12/105 (11%)

Query: 10  PGGATLLQAEEHGGLVRKKPPPAPEGK-GEPGPNDVRGGEPDGSARRPRPPCAKPHKEGT 68
           PG      A  + G      PP P G  G PG     G + +   + PR        EG 
Sbjct: 313 PGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRG------SEGP 366

Query: 69  GQQERESPRPLQLPGAEGPAISDGEEGGGEPGAGG--GAAGAAGA 111
            Q  R  P P    GA GPA + G +G  +PGA G  GA G AGA
Sbjct: 367 -QGVRGEPGPPGPAGAAGPAGNPGADG--QPGAKGANGAPGIAGA 408


>gi|116256464 hypothetical protein LOC343990 [Homo sapiens]
          Length = 962

 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 81/298 (27%), Positives = 108/298 (36%), Gaps = 45/298 (15%)

Query: 16  LQAEEHGGLVRKKPPPAPEGKGEPGPNDVRGGEPDGSARRPRPPCA----KPHKEGTGQQ 71
           L   E    +R +PP  PEG   PGP+   GG+ DG A  P  PCA    K  +     +
Sbjct: 341 LAEPESAPTLRVEPPSPPEGPPNPGPD---GGKQDGEA-PPAGPCAPATDKAEEVVCAPE 396

Query: 72  ERESPRPLQLPGAEGPAISDGEEGGGEPGAGGGAAGAAGAGRRDFVEAPPPKVNPWTKNA 131
           +  SP P  +P           EG   P     AA +     RD  E   PK    T   
Sbjct: 397 DVASPFPTAIP-----------EGDTTPPETDPAATSEAPSARDGPERSVPKEAEPTPPV 445

Query: 132 LPPVLTTVNGQSP-PEHSAPAKVVRAAVPKQRKGSKVGDFGDAINWPTPGEI-----AHK 185
           LP       G +P PE  A  +  R A  +  +         A + P P        A  
Sbjct: 446 LPDEEKGPPGPAPEPEREAETEPERGAGTEPERIGTEPSTAPAPSPPAPKSCLKHRPAAA 505

Query: 186 SVQPQSHKPQPTRKLPPKKDMKEQEKGEGS-----DSKESPKTKSDE---SGEEKNGDE- 236
           S  P +  P    + PP       E G GS      + E PK +  E   +G E+   E 
Sbjct: 506 SEGPAASPPLAAAESPP------VEPGPGSLDAEAAAPERPKAERAEAPPAGAERAAPER 559

Query: 237 DCQRGGQKKKGNKHKWVPLQIDMKPEVPREKLASRPTRPPEPRHIPANRGEIKGSESA 294
             +RGG + +G K       +      PR  + SRP      R   A  G +  SE+A
Sbjct: 560 KAERGGAELRGAK----KFSVSSCRARPRPGV-SRPLERASGRLPLARSGPVWRSEAA 612



 Score = 32.0 bits (71), Expect = 3.3
 Identities = 31/113 (27%), Positives = 40/113 (35%), Gaps = 17/113 (15%)

Query: 718 EQFDTLTPEPPVDPNQEVPPGPPRFQQ----------VPTDALANKLFGAPEPSTIARSL 767
           E   TL  EPP  P     PGP   +Q           P    A ++  APE   +A   
Sbjct: 345 ESAPTLRVEPPSPPEGPPNPGPDGGKQDGEAPPAGPCAPATDKAEEVVCAPE--DVASPF 402

Query: 768 PTTVPESPNYRNTRTP-RTPRTPQLKDSSQTSRFYPVVKEGRTLDAKMPRKRK 819
           PT +PE         P  T   P  +D  + S    V KE       +P + K
Sbjct: 403 PTAIPEGDTTPPETDPAATSEAPSARDGPERS----VPKEAEPTPPVLPDEEK 451


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 50.8 bits (120), Expect = 7e-06
 Identities = 62/231 (26%), Positives = 85/231 (36%), Gaps = 54/231 (23%)

Query: 7   PLLPGGATLLQAEEHGGLVRKKPPPAPEGKGEPG---PNDVRGGEPDGSARRP--RPPCA 61
           P+ P G T   A+  G     KPP    G  +P    P      +P G  + P  +P  A
Sbjct: 352 PVQPPGTTKPPAQPLGPA---KPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPA 408

Query: 62  KPHKEGTGQQERESPRPL-QLPGAEGPAISDG--EEGGGEPGAGGGAAGAAGAGRRDFVE 118
           KP  +  G     +P+PL Q PG + PA + G  +    +PG G   A  AG G+    +
Sbjct: 409 KPPTQQVG-----TPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQ 463

Query: 119 APPPKVNPWTKNALPPVLTTVNGQSPPEHSAPAKVVRAAVPKQRKGSKVGDFGDAINWPT 178
             P K         PP       + PP+   PAK      P Q+                
Sbjct: 464 TGPTK---------PPSQLPGPAKPPPQQPGPAKP-----PPQQ---------------- 493

Query: 179 PGEIAHKSVQPQSHKPQPTRKLPPKKDMKE--------QEKGEGSDSKESP 221
           PG     S QP S KP P +  P K   ++        Q+ G    S + P
Sbjct: 494 PGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQP 544



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 56/225 (24%), Positives = 87/225 (38%), Gaps = 40/225 (17%)

Query: 111 AGRRDFVEAPPPKV------------NPWTKNALPPVLTTVNGQSPP-EHSAPAKVVRAA 157
           A ++D  +AP PK             +P  K   PP   +++  +PP E S P++  +A 
Sbjct: 689 APKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAP 748

Query: 158 V----PKQRKGSK-VGDFGDAINWPTPGEIAHKSVQPQSHKP----------QPTRKLPP 202
           V    PKQ K  K   D   + +  T  +I    VQ Q+ +           +P++  PP
Sbjct: 749 VADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPP 808

Query: 203 KKDMKEQEKGEGSDSKESPKTKSDESGEEKNGDEDCQRGGQKKKGNKHKWVPLQIDMKPE 262
                  EK    DSK  P+  SD       G    +  GQK+        P+Q   +P+
Sbjct: 809 TG-----EKVSPFDSKAIPRPASDSKIISHPGPSS-ESKGQKQVD------PVQKKEEPK 856

Query: 263 VPREKLASRPTRPPEPRHIPANRGEIKGSESATYVPVAPPTPAWQ 307
             + K++ +P   P P+  P   G    +      P   P P  Q
Sbjct: 857 KAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQ 901



 Score = 34.3 bits (77), Expect = 0.66
 Identities = 64/302 (21%), Positives = 101/302 (33%), Gaps = 31/302 (10%)

Query: 28  KPPPAPEGKGEPGPNDVRGGEPDG--------SARRPRPPCAKPHKEGTGQQERESPRPL 79
           KPPP   G  +P P      +P          SA++P P      +      +  S +PL
Sbjct: 508 KPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPL 567

Query: 80  QLPGAEGPAISDGEEGGGEPGAGGGAAGAAGAGRRDFVEAPPPKVNPWTKNALPPVLTTV 139
           Q P     A          P  G            + +   P K N  T       + ++
Sbjct: 568 QPPTVSPSAKQ-------PPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSL 620

Query: 140 NGQSPPEHSAPAKVVRAAVPKQRKGSKVGDFGDAINWPTP----GEIAHKSVQPQSHKPQ 195
            G +P  H    K     +  Q K +  GD     + P P      +   S   +S  PQ
Sbjct: 621 CGFNPNPHLTEVK-EWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKS-SPQ 678

Query: 196 PTRKLPPKKDMKEQEKGEGSDSKESPKTKSDESGEEKNGDEDCQRGGQKKKGNKHKWVPL 255
           P +  P K    +Q+  +  + K+ P      +    +G    +     +  +  K  P 
Sbjct: 679 PQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPT---LHGSPSAKAKQPPEADSLSKPAP- 734

Query: 256 QIDMKPEVPRE--KLASRPTRPPEPRHIPANRGEIKGSESATYVPVAPPTPAW-QPEIKP 312
               +P VP E  K      +P +P+ +     ++  S SAT  P  P +    Q E K 
Sbjct: 735 --PKEPSVPSEQDKAPVADDKPKQPKMVKPTT-DLVSSSSATTKPDIPSSKVQSQAEEKT 791

Query: 313 EP 314
            P
Sbjct: 792 TP 793



 Score = 34.3 bits (77), Expect = 0.66
 Identities = 43/183 (23%), Positives = 64/183 (34%), Gaps = 37/183 (20%)

Query: 728 PVDPNQEVPPGPPRFQQVPT---------DALANKLFGAPEPSTIARSLPTTVPESPNYR 778
           P + +    P PP+   VP+         D         P    ++ S  TT P+ P+ +
Sbjct: 723 PPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSK 782

Query: 779 NTRTPRTPRTPQLK-DSSQTSRFYPVVKEGRTLDAKMPRKRKTRHSSNPPLESHVGWVMD 837
                    TP LK DS++ S+ +P   E  +       K   R +S+  + SH G   +
Sbjct: 783 VQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVS---PFDSKAIPRPASDSKIISHPGPSSE 839

Query: 838 SR----------EHRPRTASISSSPSEGT--------------PTVGSYGCTPQSLPKFQ 873
           S+          +  P+ A    SP                  PT G    TPQ  PK Q
Sbjct: 840 SKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQ 899

Query: 874 HPS 876
             S
Sbjct: 900 EQS 902


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 50.8 bits (120), Expect = 7e-06
 Identities = 62/231 (26%), Positives = 85/231 (36%), Gaps = 54/231 (23%)

Query: 7   PLLPGGATLLQAEEHGGLVRKKPPPAPEGKGEPG---PNDVRGGEPDGSARRP--RPPCA 61
           P+ P G T   A+  G     KPP    G  +P    P      +P G  + P  +P  A
Sbjct: 352 PVQPPGTTKPPAQPLGPA---KPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPA 408

Query: 62  KPHKEGTGQQERESPRPL-QLPGAEGPAISDG--EEGGGEPGAGGGAAGAAGAGRRDFVE 118
           KP  +  G     +P+PL Q PG + PA + G  +    +PG G   A  AG G+    +
Sbjct: 409 KPPTQQVG-----TPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQ 463

Query: 119 APPPKVNPWTKNALPPVLTTVNGQSPPEHSAPAKVVRAAVPKQRKGSKVGDFGDAINWPT 178
             P K         PP       + PP+   PAK      P Q+                
Sbjct: 464 TGPTK---------PPSQLPGPAKPPPQQPGPAKP-----PPQQ---------------- 493

Query: 179 PGEIAHKSVQPQSHKPQPTRKLPPKKDMKE--------QEKGEGSDSKESP 221
           PG     S QP S KP P +  P K   ++        Q+ G    S + P
Sbjct: 494 PGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQP 544



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 56/225 (24%), Positives = 87/225 (38%), Gaps = 40/225 (17%)

Query: 111 AGRRDFVEAPPPKV------------NPWTKNALPPVLTTVNGQSPP-EHSAPAKVVRAA 157
           A ++D  +AP PK             +P  K   PP   +++  +PP E S P++  +A 
Sbjct: 689 APKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAP 748

Query: 158 V----PKQRKGSK-VGDFGDAINWPTPGEIAHKSVQPQSHKP----------QPTRKLPP 202
           V    PKQ K  K   D   + +  T  +I    VQ Q+ +           +P++  PP
Sbjct: 749 VADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPP 808

Query: 203 KKDMKEQEKGEGSDSKESPKTKSDESGEEKNGDEDCQRGGQKKKGNKHKWVPLQIDMKPE 262
                  EK    DSK  P+  SD       G    +  GQK+        P+Q   +P+
Sbjct: 809 TG-----EKVSPFDSKAIPRPASDSKIISHPGPSS-ESKGQKQVD------PVQKKEEPK 856

Query: 263 VPREKLASRPTRPPEPRHIPANRGEIKGSESATYVPVAPPTPAWQ 307
             + K++ +P   P P+  P   G    +      P   P P  Q
Sbjct: 857 KAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQ 901



 Score = 34.3 bits (77), Expect = 0.66
 Identities = 64/302 (21%), Positives = 101/302 (33%), Gaps = 31/302 (10%)

Query: 28  KPPPAPEGKGEPGPNDVRGGEPDG--------SARRPRPPCAKPHKEGTGQQERESPRPL 79
           KPPP   G  +P P      +P          SA++P P      +      +  S +PL
Sbjct: 508 KPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPL 567

Query: 80  QLPGAEGPAISDGEEGGGEPGAGGGAAGAAGAGRRDFVEAPPPKVNPWTKNALPPVLTTV 139
           Q P     A          P  G            + +   P K N  T       + ++
Sbjct: 568 QPPTVSPSAKQ-------PPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSL 620

Query: 140 NGQSPPEHSAPAKVVRAAVPKQRKGSKVGDFGDAINWPTP----GEIAHKSVQPQSHKPQ 195
            G +P  H    K     +  Q K +  GD     + P P      +   S   +S  PQ
Sbjct: 621 CGFNPNPHLTEVK-EWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKS-SPQ 678

Query: 196 PTRKLPPKKDMKEQEKGEGSDSKESPKTKSDESGEEKNGDEDCQRGGQKKKGNKHKWVPL 255
           P +  P K    +Q+  +  + K+ P      +    +G    +     +  +  K  P 
Sbjct: 679 PQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPT---LHGSPSAKAKQPPEADSLSKPAP- 734

Query: 256 QIDMKPEVPRE--KLASRPTRPPEPRHIPANRGEIKGSESATYVPVAPPTPAW-QPEIKP 312
               +P VP E  K      +P +P+ +     ++  S SAT  P  P +    Q E K 
Sbjct: 735 --PKEPSVPSEQDKAPVADDKPKQPKMVKPTT-DLVSSSSATTKPDIPSSKVQSQAEEKT 791

Query: 313 EP 314
            P
Sbjct: 792 TP 793



 Score = 34.3 bits (77), Expect = 0.66
 Identities = 43/183 (23%), Positives = 64/183 (34%), Gaps = 37/183 (20%)

Query: 728 PVDPNQEVPPGPPRFQQVPT---------DALANKLFGAPEPSTIARSLPTTVPESPNYR 778
           P + +    P PP+   VP+         D         P    ++ S  TT P+ P+ +
Sbjct: 723 PPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSK 782

Query: 779 NTRTPRTPRTPQLK-DSSQTSRFYPVVKEGRTLDAKMPRKRKTRHSSNPPLESHVGWVMD 837
                    TP LK DS++ S+ +P   E  +       K   R +S+  + SH G   +
Sbjct: 783 VQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVS---PFDSKAIPRPASDSKIISHPGPSSE 839

Query: 838 SR----------EHRPRTASISSSPSEGT--------------PTVGSYGCTPQSLPKFQ 873
           S+          +  P+ A    SP                  PT G    TPQ  PK Q
Sbjct: 840 SKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQ 899

Query: 874 HPS 876
             S
Sbjct: 900 EQS 902


>gi|39812378 RAN binding protein 9 [Homo sapiens]
          Length = 729

 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 48/179 (26%), Positives = 63/179 (35%), Gaps = 22/179 (12%)

Query: 55  RPRPPCAKPHKEGTGQQERESPRPLQLPGAEG------PAISDGEEGGGEPGAGGGAAGA 108
           +P PP   P ++   QQ+   P P  L    G      PA+S G    G PG G G  G 
Sbjct: 4   QPPPP---PPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGL 60

Query: 109 AGAGRRDFVEAPPPKVNPWTKNALPPVLTTVNGQSPPEHSAPAKVVR-AAVPKQRKGSKV 167
             A     +  PPP          PP  T      PP    PA     A+ P    G   
Sbjct: 61  GAAAAALLLHPPPP----------PPPATAAPPPPPPPPPPPASAAAPASGPPAPPGLAA 110

Query: 168 GDFGDAINWPTPGEIAHKS-VQPQSHKPQPTRKLPPKKDMKEQEKGEGSDSKESPKTKS 225
           G  G A   PTP  +A  S   P  H      +   +   + +      D +E+P  +S
Sbjct: 111 GP-GPAGGAPTPALVAGSSAAAPFPHGDSALNEQEKELQRRLKRLYPAVDEQETPLPRS 168


>gi|158854042 hypothetical protein LOC222183 [Homo sapiens]
          Length = 653

 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 52/204 (25%), Positives = 74/204 (36%), Gaps = 37/204 (18%)

Query: 29  PPPAPEGKGEPGPNDV-----RGGEPDGSA----------RRPRPPCAKPHKEGTGQQER 73
           P P   GK  P P        RGG   G A          RR R   + P + G  +   
Sbjct: 354 PTPPARGKESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRP 413

Query: 74  ESPRPLQLPGAEGPAISDGEEGGGEPGAG---GGAAGAAGAGRRDFVEAPPPKVNPWTKN 130
             PR      +   + SD   G G PG G   G   G  G G+R   +  PP+  P + +
Sbjct: 414 APPRGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKR--AKERPPRARPASTS 471

Query: 131 ALPPVLTTVNGQSPPEHSAPAKVVRAAVPKQRKGSKVGDFGDAINWPTPGEIAHKSVQPQ 190
             P       G   PE  + +   R+  P  R  S         +  +P +   +S + +
Sbjct: 472 PSPGAHGRRGG---PEGKSSS---RSPGPHPRSWS---------SSRSPSKSRSRSAEKR 516

Query: 191 SHKPQPTRKLPPKKDMKEQEKGEG 214
            H   P+R   PKK +   + GEG
Sbjct: 517 PH--SPSRSPSPKKPLSRDKDGEG 538



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 42/180 (23%), Positives = 65/180 (36%), Gaps = 34/180 (18%)

Query: 178 TPGEIAHKSVQPQSHKPQPTR-----KLPPKKDMKEQEKGEGSDSKESPKTKSDESGEEK 232
           +PG  +H+     SH P  +      + P +   K +++G  + S+ S  ++S       
Sbjct: 247 SPGRRSHRHSSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGS 306

Query: 233 NGDEDCQRGGQKKKGNKHKWVPLQIDMKPEVPREKLASRPTRPPEPRHIPANRGEIKGSE 292
                 + GG  ++   H   P      P+ P           P PR        ++   
Sbjct: 307 GWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKPSS---------PSPR--------VRDKA 349

Query: 293 SATYVPVAPPTPAWQPEIKPEPAWHDQDETSSVKSDGAGGARASFRGRGRGRGRGRGRGR 352
           +A     A PTP  + +  P P        S+  S G GG  A   GR R R R R R R
Sbjct: 350 AA-----AAPTPPARGKESPSP-------RSAPSSQGRGGRAAGGAGRRRRRRRRRRRSR 397



 Score = 37.0 bits (84), Expect = 0.10
 Identities = 70/309 (22%), Positives = 103/309 (33%), Gaps = 26/309 (8%)

Query: 53  ARRPRPPCAKPHKEG--TGQQERESPRPLQLPGAEGPAISDGEEGGGE-PGAGGGAAGAA 109
           +R P     K   EG  TG Q     R     G  G        G G+  GA GG  G+A
Sbjct: 272 SRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRPGSA 331

Query: 110 GAGRRDFVEAPPPKVNPWTKNALPPVLTTVNGQSPPEHSAPAKVVRAAVPKQRKGSK-VG 168
            +   D   +P P+V      A P         +PP     +   R+A   Q +G +  G
Sbjct: 332 HSPP-DKPSSPSPRVRDKAAAAAP---------TPPARGKESPSPRSAPSSQGRGGRAAG 381

Query: 169 DFGDAINWPTPGEIAHKSVQ-PQSHKPQPTRKLPPKKDMKEQEKGEGSDSKESPKTKSDE 227
             G           +  S   P+    +  R  PP+   +   +   S    S +  +  
Sbjct: 382 GAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGR-GAPG 440

Query: 228 SGEEKNGDEDCQRGGQKKKGNKHKWVPLQIDMKPEV------PREKLASRPTRPPEPRHI 281
            G E   +      G++ K    +  P      P        P  K +SR +  P PR  
Sbjct: 441 PGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSSR-SPGPHPRSW 499

Query: 282 PANRGEIKGSESATYVPVAPPTPAWQPEIKPEPAWHDQDETSSVKSDGAGGARASFRGRG 341
            ++R   K    +      P +P+  P  K +P   D+D     +   A   RA  R R 
Sbjct: 500 SSSRSPSKSRSRS--AEKRPHSPSRSPSPK-KPLSRDKDGEGRARHSEAEATRARRRSRS 556

Query: 342 RGRGRGRGR 350
               R R R
Sbjct: 557 YSPIRKRRR 565



 Score = 35.4 bits (80), Expect = 0.30
 Identities = 31/143 (21%), Positives = 53/143 (37%), Gaps = 18/143 (12%)

Query: 26  RKKPPPAPEGKGEPGPNDVRGGEPDGSARRPRPPCAKPHKE----GTGQQERESPRPLQL 81
           R++P PAP        +  R     GS R    P  +P  E    G G++ +E P P   
Sbjct: 408 RRRPRPAPPRGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERP-PRAR 466

Query: 82  PGAEGPAISDGEEGGGEPGAGGGAAGAAGAGRRDFVEAPPPKVNPWTKNALPPVLTTVNG 141
           P +  P+          PGA G   G  G   +    +P P    W+ +  P    + + 
Sbjct: 467 PASTSPS----------PGAHGRRGGPEG---KSSSRSPGPHPRSWSSSRSPSKSRSRSA 513

Query: 142 QSPPEHSAPAKVVRAAVPKQRKG 164
           +  P   + +   +  + + + G
Sbjct: 514 EKRPHSPSRSPSPKKPLSRDKDG 536


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 61/289 (21%), Positives = 96/289 (33%), Gaps = 33/289 (11%)

Query: 29  PPPAPEGKGEPGPNDVRGGEPDGSARRPRPPCAKPHKEGTGQQERESPRPLQLPGAEGPA 88
           PP  P+G    G N  +G  P G  + P P   K     +   + + P P      +GP 
Sbjct: 74  PPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPP 133

Query: 89  ISDGEEGGGEPGAGGGAAGAAGAGRRDFVEAPPPKVNPWTKNALPPVLTTVNGQSPPEHS 148
              G+  G  P  G    G    G+    + PPP+ +  ++++  P       Q PP   
Sbjct: 134 PPPGKPQGPPPQGGNKPQGPPPPGK---PQGPPPQGDNKSRSSRSP---PGKPQGPPPQG 187

Query: 149 APAKVVRAAVPKQRKGSKVGDFGDAINWPTPGEIAHKSVQPQSHKPQPTRKLPPKKDMKE 208
                     P + +G            P PG+   +   PQ      + + PP K    
Sbjct: 188 GNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK--PQGPPPQGDNKSQSARSPPGKPQGP 245

Query: 209 QEKGEGSDSKESPKTKSDESGEEKNGDEDCQ-------------RGGQKKKGNKHKWVPL 255
             +G G+  +  P       G    G    Q             +GG K + ++      
Sbjct: 246 PPQG-GNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSP---- 300

Query: 256 QIDMKPEVPREKLASRPTRPPEPRHIPANRGEIKGSESATYVPVAPPTP 304
               KP+ P  +  ++P  PP P   P       G++     P  PP P
Sbjct: 301 --PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNK-----PQGPPPP 342



 Score = 47.4 bits (111), Expect = 8e-05
 Identities = 70/304 (23%), Positives = 99/304 (32%), Gaps = 53/304 (17%)

Query: 29  PPPAPEGKGEPGPNDVRG---------GEPDGSARRPR--PPCAKPHKEGTGQQERESPR 77
           PP  P+G    G N  +G         G P     +P+  PP  KP  +G   Q  +S  
Sbjct: 53  PPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKP--QGPPPQGDKSRS 110

Query: 78  PLQLPG-AEGPAISDGEEGGGEPGAGGGAAGAAGAGRRDFVEAPPPKVNPWTKNALPPVL 136
           P   PG  +GP    G +  G P   G   G    G     + PPP   P          
Sbjct: 111 PRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNK-PQGPPPPGKP---------- 159

Query: 137 TTVNGQSPPEHSAPAKVVRAAVPKQRKGSKVGDFGDAINWPTPGEIAHKSVQPQSHKPQP 196
                Q PP           + P + +G            P P        QPQ   P P
Sbjct: 160 -----QGPPPQGDNKSRSSRSPPGKPQG------------PPP----QGGNQPQGPPPPP 198

Query: 197 TRKLPPKKDMKEQEKGEGSDSK-ESPKTKSDESGEEKNGDEDCQRGGQKKKGNKHKWVPL 255
            +   P      + +G     K + P  + D   +         +G   + GN+ +  P 
Sbjct: 199 GKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPP- 257

Query: 256 QIDMKPEVPREKLASRPTRPPEPRH----IPANRGEIKGSESATYVPVAPPTPAW-QPEI 310
               KP+ P  +  ++P  PP P       P    + + S S    P  PP     QP+ 
Sbjct: 258 PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQG 317

Query: 311 KPEP 314
            P P
Sbjct: 318 PPPP 321



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 58/253 (22%), Positives = 81/253 (32%), Gaps = 22/253 (8%)

Query: 27  KKPPPAPEGKGEPGPNDVRGGEPDGSARRPRPPCAKPHKEGTGQQERESPRPLQLPGAEG 86
           + PP  P+G    G     G +P G    P  P   P + G   Q    P   Q P  +G
Sbjct: 174 RSPPGKPQGPPPQG-----GNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQG 228

Query: 87  PAISDGEEGGGEPGAGGGAAGAAGAGRRDFVEAPPPKVNPWTKNALPPVLTTVNGQSPPE 146
              +  +     PG   G     G    +  + PPP   P  K   PP       Q PP 
Sbjct: 229 D--NKSQSARSPPGKPQGPPPQGG----NQPQGPPP---PPGKPQGPPPQGGNKPQGPPP 279

Query: 147 HSAPAKVVRAAVPKQRKGSKVGDFGDAINWPTPGEIAHKSVQPQSHKPQPTRKLPPKKDM 206
              P        P  + GSK          P  G       QPQ   P P +   P    
Sbjct: 280 PGKPQG------PPPQGGSKSRSSRSPPGKP-QGPPPQGGNQPQGPPPPPGKPQGPPPQG 332

Query: 207 KEQEKGEGSDSK-ESPKTKSDESGEEKNGDEDCQRGGQKKKGNKHKWVPLQIDMKPEVPR 265
             + +G     K + P  +               +G  +++GN  +  P      P+ P+
Sbjct: 333 GNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQ 392

Query: 266 EKLASRPTRPPEP 278
              A +P  PP P
Sbjct: 393 APPAGQPQGPPRP 405



 Score = 44.3 bits (103), Expect = 6e-04
 Identities = 62/261 (23%), Positives = 85/261 (32%), Gaps = 36/261 (13%)

Query: 22  GGLVRKKPPPAPEGKGEP-GPNDVRGGEPDGSARRPRPPCAKPHKEGTGQQERESPRPLQ 80
           GG   + PPP P   G+P GP    G +P G     +P    P  +   Q  R  P   Q
Sbjct: 187 GGNQPQGPPPPP---GKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQ 243

Query: 81  LPGAEGPAISDGEEGGGEPGAGGGAAGAAGAGRRDFVEAPPPKVNPWTKNALPPVLTTVN 140
            P  +G     G +  G P   G   G    G     + PPP   P              
Sbjct: 244 GPPPQG-----GNQPQGPPPPPGKPQGPPPQGGNK-PQGPPPPGKPQGP----------- 286

Query: 141 GQSPPEHSAPAKVVRAAVPKQRKGSKVGDFGDAINWPTPGEIAHKSVQPQSHKPQ----P 196
              PP+  + ++  R+   K +     G        P PG+       PQ   PQ    P
Sbjct: 287 ---PPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGK-------PQGPPPQGGNKP 336

Query: 197 TRKLPPKKDMKEQEKGEGSDSKESPKTKSDESGEEKNGDEDCQRGGQKKKGNKHKWVPLQ 256
               PP K      +G GS S+ +        G  +    + Q       GN  +     
Sbjct: 337 QGPPPPGKPQGPPPQG-GSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPP 395

Query: 257 IDMKPEVPREKLASRPTRPPE 277
                  PR     RP+RPP+
Sbjct: 396 AGQPQGPPRPPQGGRPSRPPQ 416



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 77/312 (24%), Positives = 104/312 (33%), Gaps = 62/312 (19%)

Query: 27  KKPPPAPEGKGEPGPNDVRG---------GEPDGSARRPR--PPCAKPHKEGTGQQERES 75
           + PP  P+G    G N  +G         G P     +P+  PP  KP  +G   Q    
Sbjct: 112 RSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKP--QGPPPQGDNK 169

Query: 76  PRPLQLPGA--EGPAISDGEEGGGEPGAGGGAAGAAGAGRRDFVEAPPPKVNPWTKNALP 133
            R  + P    +GP    G +  G P   G   G    G     + PPP   P       
Sbjct: 170 SRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNK-PQGPPPPGKP------- 221

Query: 134 PVLTTVNGQSPPEHSAPAKVVRAAVPKQRKGSKVGDFGDAINWPTPGEIAHKSVQPQSHK 193
                     PP+    ++  R+   K +     G        P PG       +PQ   
Sbjct: 222 -------QGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPG-------KPQGPP 267

Query: 194 PQ----PTRKLPPKKDMKEQEKGEGSDSKESPKTKSDESGEEKNGDEDCQRGGQKKKGNK 249
           PQ    P    PP K      +G GS S+ S        G          +GG + +G  
Sbjct: 268 PQGGNKPQGPPPPGKPQGPPPQG-GSKSRSSRSPPGKPQGPP-------PQGGNQPQG-- 317

Query: 250 HKWVPLQIDMKPEVPREKLASRPTRPPEP--RHIPANRGEIKGSESATYVPVAPPTPAWQ 307
               P     KP+ P  +  ++P  PP P     P  +G  K S SA   P  P  P  Q
Sbjct: 318 ----PPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSK-SRSARSPPGKPQGPPQQ 372

Query: 308 ----PEIKPEPA 315
               P+  P PA
Sbjct: 373 EGNNPQGPPPPA 384


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 71/311 (22%), Positives = 108/311 (34%), Gaps = 35/311 (11%)

Query: 26  RKKPPPAPEGKGEPGPNDVRGGEPDGSARR--PRPPCAKPHKEGTGQQERESPRPLQLPG 83
           R  PP        P P       P    RR  P PP  +        ++R SP    +  
Sbjct: 595 RYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSP----VTK 650

Query: 84  AEGPAISDGEEGGGEPGAGGGAAGAAGAGRRDFVEAPPPKVN-PWTKNALPPVLTTVNG- 141
              P++S     G  P      A +    +R    +P P+   P T ++ PPV    +  
Sbjct: 651 RRSPSLSSKHRKGSSPSRSTREARSPQPNKR---HSPSPRPRAPQTSSSPPPVRRGASSS 707

Query: 142 ----QSPPEHSAPAKVVRAAVPKQRKGSKVGDFGDAINWPTPGEIAH-KSVQPQSHKPQP 196
               QSP   + P + V +  P+ +K  K          P+P  +    S +  S  P+P
Sbjct: 708 PQRRQSPSPSTRPIRRV-SRTPEPKKIKKAAS-------PSPQSVRRVSSSRSVSGSPEP 759

Query: 197 TRKLPPKKDMKEQEKGEGSDSKES---PKTKSDESGEEKNGDEDCQRGGQKKK---GNKH 250
             K PP      Q +   ++   +    K KS         + D + GG+KKK     KH
Sbjct: 760 AAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKH 819

Query: 251 KWVPLQIDMKPEVPREKLASRPTRPPEPRHIPANRGEIKGSESATYVPVAPPTPAWQPEI 310
           K        K     + +A+       P  I A    +   E     PVA P P  + E 
Sbjct: 820 KKDKKHKKHKKHKKEKAVAAAAAAAVTPAAIAAATTTLAQEE-----PVAAPEPKKETES 874

Query: 311 KPEPAWHDQDE 321
           + E    D ++
Sbjct: 875 EAEDNLDDLEK 885



 Score = 39.3 bits (90), Expect = 0.021
 Identities = 38/147 (25%), Positives = 60/147 (40%), Gaps = 28/147 (19%)

Query: 724 TPEPPVDPNQEVPPGPPRFQQVPTDALANKLFGAPEPSTIARSLPTTVPESPNY------ 777
           +P PP       PP PP+ +  P+     ++  +P P    RS P T   SP+       
Sbjct: 605 SPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPK--QRSSPVTKRRSPSLSSKHRK 662

Query: 778 -----RNTRTPRTPRTPQLKDSS------QTSRFYPVVKEGRTLDAKMPRKRKTRHSSNP 826
                R+TR  R+P+  +    S      QTS   P V+ G    +  P++R++   S  
Sbjct: 663 GSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGA---SSSPQRRQSPSPSTR 719

Query: 827 PLESHVGWVMDSREHRPRTASISSSPS 853
           P+         SR   P+    ++SPS
Sbjct: 720 PIR------RVSRTPEPKKIKKAASPS 740



 Score = 38.9 bits (89), Expect = 0.027
 Identities = 74/383 (19%), Positives = 127/383 (33%), Gaps = 63/383 (16%)

Query: 10  PGGATLLQAEEHGGLVRKKPPPAPEGKGEPGPNDVRGGEPDGSARRPRPPCAKPHKEGTG 69
           PG  +    +  G   R+ P PAP+    P   ++   E D   +       +  ++   
Sbjct: 432 PGRTSGKVTKHKGTEKRESPSPAPK----PRKVELSESEEDKGGKMAAADSVQQRRQYRR 487

Query: 70  QQERESPRPLQLPGAEGPA-----ISDGEEG---------GGEPGAGGGAAGAAGAGRRD 115
           Q ++ S        +E        + +GE G            P         +  GRR 
Sbjct: 488 QNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRR 547

Query: 116 FVEAPPPKVNPWTKNALPPVLTTVNGQSPPEHSAPAKVVRAAVPKQRK----------GS 165
              +PPP     + +  PP         PP    P+   R   P  R+           S
Sbjct: 548 RSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPS 607

Query: 166 KVGDFGDAINWPTPGEIAHKSVQPQ---SHKPQPTRKLPP-----KKDMKEQEKGEGSDS 217
                  A   P P   A  S  P+   SH P P ++  P        +  + +   S S
Sbjct: 608 PPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPS 667

Query: 218 KESPKTKSDE------------SGEEKNGDEDCQRGG----QKKKGNKHKWVPL-QIDMK 260
           + + + +S +            + +  +     +RG     Q+++       P+ ++   
Sbjct: 668 RSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRT 727

Query: 261 PEVPREKLASRPTRPPEPRHIPANRGEIKGSESATYVPVAPPTPA--------WQPEIKP 312
           PE  + K A+ P+ P   R + ++R      E A   P APP+P         W P +  
Sbjct: 728 PEPKKIKKAASPS-PQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPV 786

Query: 313 EPAWHDQDETSSVK-SDGAGGAR 334
           + A       S  + SD  GG +
Sbjct: 787 KKAKSPTPSPSPPRNSDQEGGGK 809



 Score = 36.6 bits (83), Expect = 0.13
 Identities = 30/101 (29%), Positives = 40/101 (39%), Gaps = 8/101 (7%)

Query: 731 PNQEVPPGPPRFQQVPTDALANKLFGAPEPSTIARSLPTTVPESPNYRNTRTP----RTP 786
           P++   P P R +Q  T     +      P T  R  P+  P  P  R T TP    RTP
Sbjct: 525 PSRSASPSP-RKRQKETSPRGRRRRSPSPPPTRRRRSPSPAP-PPRRRRTPTPPPRRRTP 582

Query: 787 RTPQLKDSSQTSRFYPVVKEGRTLDAKMPRKRKTRHSSNPP 827
             P  + S    R+ P ++  R      P KR+T     PP
Sbjct: 583 SPPPRRRSPSPRRYSPPIQ--RRYSPSPPPKRRTASPPPPP 621



 Score = 33.1 bits (74), Expect = 1.5
 Identities = 65/333 (19%), Positives = 102/333 (30%), Gaps = 56/333 (16%)

Query: 28  KPPPAPEGKGEPGPNDVRGGEPDGSARRPRPPCAKPHKEGTGQQERESPRPLQLPGAEGP 87
           KP P PE K EP P      E +    RPR       +  T  +     RP +   +   
Sbjct: 249 KPEPIPEPK-EPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSR 307

Query: 88  AISDGEEGGGEPGAGGGAAGAAGAGRRDFVEAPPPKVNPWTKNALPPVLTTVNGQSPPEH 147
           + S                             P P+  P  +   PP         PP H
Sbjct: 308 SYSPRRR-------------------------PSPRRRPSPRRRTPPRRMP----PPPRH 338

Query: 148 SAPAKVVRAAVPKQRKGSKVGDFGDAINWPTPGEIAHKSVQPQSHKPQPTRKLPPKKDMK 207
                 VR    ++R  + +     + +         K  +  S  P+ TR+L P     
Sbjct: 339 RRSRSPVRR---RRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPP 395

Query: 208 EQEKGEGSDSKESPKTKSDESGEEKNGDE----DCQRGGQKKKGNKHKWVPLQIDMKPEV 263
            +       +   PKT+   + ++ N           G    K  KHK            
Sbjct: 396 RRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGT---------- 445

Query: 264 PREKLASRPTRPPEPRHIPANRG-EIKGSESATYVPVAPPTPAWQPEIKPEPAWHDQDET 322
             EK  S P+  P+PR +  +   E KG + A     A  +   + + + +      D  
Sbjct: 446 --EKRES-PSPAPKPRKVELSESEEDKGGKMA-----AADSVQQRRQYRRQNQQSSSDSG 497

Query: 323 SSVKSDGAGGARASFRGRGRGRGRGRGRGRGGT 355
           SS  S+     R+  +    GR R     R  +
Sbjct: 498 SSSSSEDERPKRSHVKNGEVGRRRRHSPSRSAS 530



 Score = 30.4 bits (67), Expect = 9.6
 Identities = 28/106 (26%), Positives = 42/106 (39%), Gaps = 17/106 (16%)

Query: 760 PSTIARSLPTTVPESPNYRNTRTPRTPRTPQ------LKDSSQTSRFYPVVKEGRTLDAK 813
           PS   R+ P  +P  P +R +R+P   R            SS +SR     K+     + 
Sbjct: 321 PSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSS 380

Query: 814 MPRK-RKTRHSSNPPLESHVGWVMDSREHRPRTASISSSPSEGTPT 858
            PRK R+   S++PP           R HRP   +     +  +PT
Sbjct: 381 PPRKTRRLSPSASPP----------RRRHRPSPPATPPPKTRHSPT 416


>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
           [Homo sapiens]
          Length = 916

 Score = 48.1 bits (113), Expect = 4e-05
 Identities = 63/234 (26%), Positives = 93/234 (39%), Gaps = 21/234 (8%)

Query: 17  QAEEHGGLVRKKP--PPAPEGKGEPGPNDVRGG-----EPDGSARRPRPPCAKPHKEGTG 69
           +AEE     +K P    APE K E G  +   G     E D  A+  +       KEG+ 
Sbjct: 500 EAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSS 559

Query: 70  QQER----ESPRPLQLPGAEGPAISDG--EEGGGEPGAGGGAAGAAGAGRRDFVEAPPPK 123
           ++E     E     +  G E  A  +   EE   E          A   + +  ++P PK
Sbjct: 560 EKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPK 619

Query: 124 --VNPWTKNALPPVLTTVNGQSPPEHSAPAKVVRAAVPKQRKGSKVGDFGDAINWPTPGE 181
             V    K+ +P       G+SP   S   +  ++ VPK    S V + G +    +P E
Sbjct: 620 SPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPK----SPVEEKGKSPVSKSPVE 675

Query: 182 IAHKSVQPQSHKPQPTRKLPPKKDMKEQEKGEGSDSKESPKTKSDESGEEKNGD 235
              KS  P+S  P    K   +    EQ++ E  + KE+PK +  E  EEK  D
Sbjct: 676 EKAKSPVPKS--PVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKD 727



 Score = 34.3 bits (77), Expect = 0.66
 Identities = 46/223 (20%), Positives = 82/223 (36%), Gaps = 31/223 (13%)

Query: 117 VEAPPPKVNPWTKNALPPVLTTVNGQSPPEHSAPAKVVRAAVPKQRKGSKVGDFGDAINW 176
           VEAP  KV       +       + +S  E +  A     AV  + +  +  +  +    
Sbjct: 441 VEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPE 500

Query: 177 PTPGEIAHKSVQPQSHKPQPTRKLPPKKDMKEQEKGEGSDSKESPKTKSD---ESGEEKN 233
               E+A K    ++  P+    +  ++  KE+E+G+  + +E    KSD   E G EK 
Sbjct: 501 AEEEEVAAKKSPVKATAPE----VKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKE 556

Query: 234 GDEDCQRGGQK---------------KKGNKHKWVPLQIDMKPEVPREKLASRPTRPPEP 278
           G  + + G Q+               K+  K +    ++  K E+  +    +P +   P
Sbjct: 557 GSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSP 616

Query: 279 RHIPANRGEIKGSESATYVPV-------APPTPAWQPEIKPEP 314
             +P +  E KG       PV        P +P  +    P P
Sbjct: 617 --VPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVP 657



 Score = 33.9 bits (76), Expect = 0.87
 Identities = 28/134 (20%), Positives = 52/134 (38%), Gaps = 15/134 (11%)

Query: 133 PPVLTTVNGQSPPEHSAPAKVVRAAVPKQRKGSKVGDFGDAINWPTPGEIAHKSVQPQSH 192
           PP+  +   Q P   +   KV    V +  + +KV D    +           +V  +  
Sbjct: 428 PPITISSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEE 487

Query: 193 KPQPTRKLPPKKDMKEQE--------KGEGSDSKESPKTKSDESGEEKNGDED------- 237
           K +   +   + + +E+E        K    + KE    K +E G+E+  +ED       
Sbjct: 488 KKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQ 547

Query: 238 CQRGGQKKKGNKHK 251
            + GG +K+G+  K
Sbjct: 548 AEEGGSEKEGSSEK 561



 Score = 33.5 bits (75), Expect = 1.1
 Identities = 53/264 (20%), Positives = 104/264 (39%), Gaps = 37/264 (14%)

Query: 12  GATLLQAEEHGGLVRKKPPPAPEGKGEPGPNDVRGGEPDGSARRPRPPCAKPHKEGTGQQ 71
           GA   QAEE GG  ++      EG+ E G  +      +  A+  +    K  +  T ++
Sbjct: 542 GAKSDQAEE-GGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEE 600

Query: 72  -----ERESPRPLQLPGAEGPAISDGEEGGGE-PGAGGGAAGAAGAGRRDFVEAPPPKVN 125
                + E P   + P  + P    G+    + P    G +    +   +  ++P PK +
Sbjct: 601 LVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPK-S 659

Query: 126 PWTKNALPPVLTTVNGQSPPEHSAPAKVVRAAVPKQRKGSKVG-------DFGDAINWPT 178
           P  +    PV      +SP E  A + V ++ V + +  ++VG       +  +    P 
Sbjct: 660 PVEEKGKSPV-----SKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPK 714

Query: 179 PGEIAHKSVQPQSHKPQPTRKLPPKKD---------------MKEQEKGEGSD-SKESPK 222
             ++  K  +P+    +   + P K++               ++++ K EG    +E  K
Sbjct: 715 EEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEK 774

Query: 223 TKSD-ESGEEKNGDEDCQRGGQKK 245
            K+  E G E+ G +   +G +K+
Sbjct: 775 EKAGGEGGSEEEGSDKGAKGSRKE 798


>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
           [Homo sapiens]
          Length = 540

 Score = 48.1 bits (113), Expect = 4e-05
 Identities = 63/234 (26%), Positives = 93/234 (39%), Gaps = 21/234 (8%)

Query: 17  QAEEHGGLVRKKP--PPAPEGKGEPGPNDVRGG-----EPDGSARRPRPPCAKPHKEGTG 69
           +AEE     +K P    APE K E G  +   G     E D  A+  +       KEG+ 
Sbjct: 124 EAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSS 183

Query: 70  QQER----ESPRPLQLPGAEGPAISDG--EEGGGEPGAGGGAAGAAGAGRRDFVEAPPPK 123
           ++E     E     +  G E  A  +   EE   E          A   + +  ++P PK
Sbjct: 184 EKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPK 243

Query: 124 --VNPWTKNALPPVLTTVNGQSPPEHSAPAKVVRAAVPKQRKGSKVGDFGDAINWPTPGE 181
             V    K+ +P       G+SP   S   +  ++ VPK    S V + G +    +P E
Sbjct: 244 SPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPK----SPVEEKGKSPVSKSPVE 299

Query: 182 IAHKSVQPQSHKPQPTRKLPPKKDMKEQEKGEGSDSKESPKTKSDESGEEKNGD 235
              KS  P+S  P    K   +    EQ++ E  + KE+PK +  E  EEK  D
Sbjct: 300 EKAKSPVPKS--PVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKD 351



 Score = 34.3 bits (77), Expect = 0.66
 Identities = 46/223 (20%), Positives = 82/223 (36%), Gaps = 31/223 (13%)

Query: 117 VEAPPPKVNPWTKNALPPVLTTVNGQSPPEHSAPAKVVRAAVPKQRKGSKVGDFGDAINW 176
           VEAP  KV       +       + +S  E +  A     AV  + +  +  +  +    
Sbjct: 65  VEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPE 124

Query: 177 PTPGEIAHKSVQPQSHKPQPTRKLPPKKDMKEQEKGEGSDSKESPKTKSD---ESGEEKN 233
               E+A K    ++  P+    +  ++  KE+E+G+  + +E    KSD   E G EK 
Sbjct: 125 AEEEEVAAKKSPVKATAPE----VKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKE 180

Query: 234 GDEDCQRGGQK---------------KKGNKHKWVPLQIDMKPEVPREKLASRPTRPPEP 278
           G  + + G Q+               K+  K +    ++  K E+  +    +P +   P
Sbjct: 181 GSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSP 240

Query: 279 RHIPANRGEIKGSESATYVPV-------APPTPAWQPEIKPEP 314
             +P +  E KG       PV        P +P  +    P P
Sbjct: 241 --VPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVP 281



 Score = 33.9 bits (76), Expect = 0.87
 Identities = 28/134 (20%), Positives = 52/134 (38%), Gaps = 15/134 (11%)

Query: 133 PPVLTTVNGQSPPEHSAPAKVVRAAVPKQRKGSKVGDFGDAINWPTPGEIAHKSVQPQSH 192
           PP+  +   Q P   +   KV    V +  + +KV D    +           +V  +  
Sbjct: 52  PPITISSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEE 111

Query: 193 KPQPTRKLPPKKDMKEQE--------KGEGSDSKESPKTKSDESGEEKNGDED------- 237
           K +   +   + + +E+E        K    + KE    K +E G+E+  +ED       
Sbjct: 112 KKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQ 171

Query: 238 CQRGGQKKKGNKHK 251
            + GG +K+G+  K
Sbjct: 172 AEEGGSEKEGSSEK 185



 Score = 33.5 bits (75), Expect = 1.1
 Identities = 53/264 (20%), Positives = 104/264 (39%), Gaps = 37/264 (14%)

Query: 12  GATLLQAEEHGGLVRKKPPPAPEGKGEPGPNDVRGGEPDGSARRPRPPCAKPHKEGTGQQ 71
           GA   QAEE GG  ++      EG+ E G  +      +  A+  +    K  +  T ++
Sbjct: 166 GAKSDQAEE-GGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEE 224

Query: 72  -----ERESPRPLQLPGAEGPAISDGEEGGGE-PGAGGGAAGAAGAGRRDFVEAPPPKVN 125
                + E P   + P  + P    G+    + P    G +    +   +  ++P PK +
Sbjct: 225 LVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPK-S 283

Query: 126 PWTKNALPPVLTTVNGQSPPEHSAPAKVVRAAVPKQRKGSKVG-------DFGDAINWPT 178
           P  +    PV      +SP E  A + V ++ V + +  ++VG       +  +    P 
Sbjct: 284 PVEEKGKSPV-----SKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPK 338

Query: 179 PGEIAHKSVQPQSHKPQPTRKLPPKKD---------------MKEQEKGEGSD-SKESPK 222
             ++  K  +P+    +   + P K++               ++++ K EG    +E  K
Sbjct: 339 EEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEK 398

Query: 223 TKSD-ESGEEKNGDEDCQRGGQKK 245
            K+  E G E+ G +   +G +K+
Sbjct: 399 EKAGGEGGSEEEGSDKGAKGSRKE 422


>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
          Length = 2944

 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 75/282 (26%), Positives = 96/282 (34%), Gaps = 44/282 (15%)

Query: 10   PGGATLLQAEEHGGLVRKKPPPAPEG-KGEPGPNDVRGGEPDGSARRPRPPCAKPHKEGT 68
            P G  +   E   GL  ++ PP  +G KGEPG N  +G + D      +    +P   G 
Sbjct: 2089 PPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQ 2148

Query: 69   GQQ-----ERESPRPLQLPGAEGPAISDGEEGG-GEPGAGG--GAAGAAGAGRRDFVEAP 120
                    ER    P   PG +GP    G  GG G+PG  G  G AG AG      ++  
Sbjct: 2149 DGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGE 2208

Query: 121  PPKVNPWTKNALPPVLTTVNGQSPPEHSA----------PAKVVRAAVP--KQRKGSKVG 168
            P +  P  +    P    V    PP  S           P +V     P    R G+  G
Sbjct: 2209 PGETGPPGRGLTGPT-GAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGAS-G 2266

Query: 169  DFGDAINWPTPGEIAHKSVQPQSHKPQPTRK-------LPPKKDMKEQEKGEGSDSKESP 221
              GD  +   PG            +P PT         LP  K  K    G   D    P
Sbjct: 2267 KDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEP 2326

Query: 222  KTKSD--------------ESGEEKNGDEDCQRGGQKKKGNK 249
              K D               +GE  +  ED Q+G    KG K
Sbjct: 2327 GAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFK 2368



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 59/215 (27%), Positives = 82/215 (38%), Gaps = 15/215 (6%)

Query: 7    PLLPGGATLLQAEEHGGLVRKKPPPAP-EGKGEPGPNDVRGGEPDGSARRPRPPCAKPHK 65
            P LPG   +   E   GL   + PP P  G G+PGP    G       + P     +P +
Sbjct: 2152 PGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGE 2211

Query: 66   EGTGQQERESPR-PLQLPGAEGPAISDGEEGG-GEPGAGG-----GAAGAAGAGRRDFVE 118
             G   +    P   + LPG  GP+   G +G  G PG  G     GA G  GA  +D   
Sbjct: 2212 TGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDR 2271

Query: 119  APPPKVNPWTKNALPPVLTTVNGQSPPEHSAPAKVVRAAVPKQRKGSKVGDFGDAINWPT 178
              P    P +     PV     G+  P  +    VV     K  KG+  G  GD +    
Sbjct: 2272 GSPGV--PGSPGLPGPV--GPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVG--E 2325

Query: 179  PGEIAHKSVQ-PQSHKPQPTRKLPPKKDMKEQEKG 212
            PG    + +  P+  K +  R   P    ++ +KG
Sbjct: 2326 PGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKG 2360



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 38/108 (35%), Positives = 43/108 (39%), Gaps = 22/108 (20%)

Query: 30   PPAPEGK-GEPGPNDVRGGEP-DGSARRPRPPCAKPHKEGTGQQE-----RESPRPLQLP 82
            PP P G+  + GP     GEP D     PR P   P   G   +      R  P P   P
Sbjct: 1701 PPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDP 1760

Query: 83   GAEGPAISDGEEG----------GGEPGAGG-----GAAGAAGAGRRD 115
            G  GPA   G+ G           G+PGA G     GAAG AG   RD
Sbjct: 1761 GVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRD 1808



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 81/324 (25%), Positives = 107/324 (33%), Gaps = 51/324 (15%)

Query: 5    VEPLLPGGATLLQAEEHGGLVRKKPPPA--PEG-KGEPGPNDVRG-----GEPDGSARRP 56
            ++  + G AT L         R +P P   P+G KGEPG   +RG     G+P    R  
Sbjct: 1222 LDQAVSGLATALCQASFTTQPRPEPCPVYCPKGQKGEPGEMGLRGQVGPPGDPGLPGRTG 1281

Query: 57   RPPCAKPHKEGTGQQERESPRPLQLPGAEGPAISDGEEGG-------------------- 96
             P    P    T + ER  P     PG+ G A + G  G                     
Sbjct: 1282 APGPQGPPGSATAKGERGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERG 1341

Query: 97   -----GEPGAGGGAAGAAGAGRRDFVEAPPPKVNPWTKNALPPVLTTVNGQSPPEHSAPA 151
                 GEPGA G   G  G G       P P   P  +      L     + PP    P 
Sbjct: 1342 PRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRGP----LGDPGPRGPP--GLPG 1395

Query: 152  KVVRAAVPKQRKGSKVGDFGDAINWPTPGEIAHKSVQPQSHKPQPTRKLPPKKDMK-EQE 210
              ++    K  +G + G  G       PGE     + P S  PQ     P KK  K + E
Sbjct: 1396 TAMKG--DKGDRGER-GPPGPGEGGIAPGEPGLPGL-PGSPGPQGPVGPPGKKGEKGDSE 1451

Query: 211  KG-------EGSDSKESPKTKSDESGEEKNGDEDCQRGGQKKKGNKHKWVPLQIDMKPEV 263
             G        GS  ++ P+      G + +       G   +KG +    P      P V
Sbjct: 1452 DGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGV 1511

Query: 264  PREKLASRPTRPPEPRHIPANRGE 287
                 A  P  PP P      +GE
Sbjct: 1512 AGRPGAKGPEGPPGPTGRQGEKGE 1535



 Score = 38.5 bits (88), Expect = 0.035
 Identities = 33/95 (34%), Positives = 40/95 (42%), Gaps = 11/95 (11%)

Query: 27   KKPPPAPEG-KGEPGPNDVRG----GEPDGSARRPRPPCAKPHKEGTGQQERESPRPLQ- 80
            ++ PP P G  GEPG   + G        G A RP     +  K   G+Q R+ P  L  
Sbjct: 2023 ERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPG 2082

Query: 81   ---LPGAEGPAISDGEEGGGEPGAGG--GAAGAAG 110
                PG  GP +S  E G G  G  G  G  GA G
Sbjct: 2083 TPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKG 2117



 Score = 37.0 bits (84), Expect = 0.10
 Identities = 74/312 (23%), Positives = 103/312 (33%), Gaps = 65/312 (20%)

Query: 22   GGLVRKKPPPAPEGKGEPGPNDVRGGEPDGSARRPRPPCAKPHKEGTGQQERESPRPLQL 81
            G ++  + P  P  KG+PGP+   G         PR P   P   G          P  L
Sbjct: 1353 GQVIGGEGPGLPGRKGDPGPSGPPG---------PRGPLGDPGPRG----------PPGL 1393

Query: 82   PGA--EGPAISDGEEGGGEPGAGGGAAGAAGAGRRDFVEAPPPKVNPWTKNALPPVLTTV 139
            PG   +G     GE G   PG GG A G  G         P   V P  K          
Sbjct: 1394 PGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKK--------- 1444

Query: 140  NGQSPPEHSAPAKVVRAAVP-KQRKGSKVGDFGDAINWPTPGEIAHKSVQPQSHKPQP-- 196
              +   E  AP    +   P +Q      G  G   +   PG +     + +   P P  
Sbjct: 1445 GEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAG 1504

Query: 197  TRKLPPKKDMKEQEKGEGSDSKESPKTKSDESGEE-KNGDE----DCQRGGQKKKGNKHK 251
            +R LP    +  +   +G +    P  +  E GE  + GD         G + +KG    
Sbjct: 1505 SRGLP---GVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKG---- 1557

Query: 252  WVPLQIDMKPEVPREKLASRPTR---------PPEPRHIPANRGEIKGSESATYVPVAPP 302
                  D+ P  PR     +  R          P P+  P +RG I  +  A      PP
Sbjct: 1558 ------DVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRA-----GPP 1606

Query: 303  TPAWQPEIKPEP 314
              +  P  K +P
Sbjct: 1607 GDSGPPGEKGDP 1618



 Score = 35.8 bits (81), Expect = 0.23
 Identities = 31/96 (32%), Positives = 39/96 (40%), Gaps = 10/96 (10%)

Query: 29   PPPAPEGKGEPGPNDVRG--GEPDGSARRPRPPCAKPHKEG-TGQQERESPRPLQLPGAE 85
            PP  P   G PG + ++G  G+P      PR    +P   G  G+  +E PR     G  
Sbjct: 2441 PPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPR-----GLT 2495

Query: 86   GPAISDGEEGGGEPGAGGGAAGAAGAGRRDFVEAPP 121
            GP  S GE   GE G  G A      G    +  PP
Sbjct: 2496 GPPGSRGER--GEKGDVGSAGLKGDKGDSAVILGPP 2529



 Score = 33.1 bits (74), Expect = 1.5
 Identities = 37/118 (31%), Positives = 46/118 (38%), Gaps = 13/118 (11%)

Query: 10   PGGATLLQAEEHGGLVRKKPPPAPEG-KGEPGPNDVRGGEP-----DGSARRPRPPCAKP 63
            PG   L+  +   G   +  P   +G KGE G   + GG P     DGSA  P PP +  
Sbjct: 2673 PGKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTPGI-GGFPGPSGNDGSAGPPGPPGSVG 2731

Query: 64   HKEGTGQQ----ERESP--RPLQLPGAEGPAISDGEEGGGEPGAGGGAAGAAGAGRRD 115
             +   G Q    ER  P  R +  PG  G     GE+G   P    G  G A     D
Sbjct: 2732 PRGPEGLQGQKGERGPPGERVVGAPGVPGAPGERGEQGRPGPAGPRGEKGEAALTEDD 2789



 Score = 32.7 bits (73), Expect = 1.9
 Identities = 34/119 (28%), Positives = 42/119 (35%), Gaps = 23/119 (19%)

Query: 10   PGGATLLQAEEHGGLVRKKPPPAPEGK----GEPGPNDVRG--GEPDGSARRPRPPCAKP 63
            PG   L       GL     PP   GK    G+PG N   G  G+P    R+      K 
Sbjct: 1805 PGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGE----KG 1860

Query: 64   HKEGTGQQERESPR----------PLQLPGAEGPAISDGEEGGGEPGAGGGAAGAAGAG 112
                +G++ R+ P+          P   PG  GP    G  G G PG  GG       G
Sbjct: 1861 DSGASGREGRDGPKGERGAPGILGPQGPPGLPGPV---GPPGQGFPGVPGGTGPKGDRG 1916



 Score = 32.3 bits (72), Expect = 2.5
 Identities = 32/99 (32%), Positives = 38/99 (38%), Gaps = 16/99 (16%)

Query: 31   PAPEG-KGEPGPNDVRGGEPDGSARRPRPPCAKPHKEGTGQQERESPRPLQLPGAEGPAI 89
            P  +G KG PGP   +G    G    P PP     K   G           LPGA G   
Sbjct: 2353 PGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLP--------GLPGAPGVVG 2404

Query: 90   SDGEEGG----GEPGAGGGAAGAAGAGRRDFVEAP--PP 122
              G+ G     G+PG   G  G AG   R+ +  P  PP
Sbjct: 2405 FPGQTGPRGEMGQPGP-SGERGLAGPPGREGIPGPLGPP 2442



 Score = 32.0 bits (71), Expect = 3.3
 Identities = 28/99 (28%), Positives = 37/99 (37%), Gaps = 11/99 (11%)

Query: 30   PPAPEGK----GEPGPNDVRGGEPDGSARRPRPPCAKPHKEGTGQQERESPRPLQ-LPGA 84
            PP  +G     G PGP   RG + +   +    P   P   G     +   R L+  PG 
Sbjct: 1611 PPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPG-----KAGERGLRGAPGV 1665

Query: 85   EGPAISDGEEGG-GEPGAGGGAAGAAGAGRRDFVEAPPP 122
             GP    G++G  GE G  G    +   G R     P P
Sbjct: 1666 RGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGP 1704



 Score = 30.8 bits (68), Expect = 7.3
 Identities = 95/400 (23%), Positives = 130/400 (32%), Gaps = 97/400 (24%)

Query: 5    VEPLLPGGATLLQAEEHGGLVRKKPPPAPEGKGEPGPNDVRGGE-PDGSARRPRPPCAKP 63
            V P  P GAT +Q E        + PP     G+PGP    G   P G   R  PP    
Sbjct: 1559 VGPAGPRGATGVQGE--------RGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPP---- 1606

Query: 64   HKEGTGQQERESPRPLQLPGAEGPAISDGEEGGGEPGAGGGAAGAAGAGRRDFVEAPPPK 123
                               G  GP    G+ G   P    G  G  G       E PP  
Sbjct: 1607 -------------------GDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPP-- 1645

Query: 124  VNPWTKNALPPVLTTVNGQSPPEHSAPAKVVRAAVPKQRKGSKVGDFGDAINWPTPGEIA 183
                    LP       G++       A  VR   P   KG + GD G+     +PG   
Sbjct: 1646 ----GDPGLP-------GKAGERGLRGAPGVRG--PVGEKGDQ-GDPGEDGRNGSPGSSG 1691

Query: 184  HKSVQPQSHKPQPTRKLPPKKDMKEQEKGE-GSDSKESPKTKSDESG----------EEK 232
             K  + +   P P  +L        +EKGE G   +E P+    + G          E  
Sbjct: 1692 PKGDRGEPGPPGPPGRL-VDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGF 1750

Query: 233  NGDEDCQ-----RGGQKKKGNKHKWVPLQIDMKPEVPREKLASRPTRP---------PEP 278
             G    Q     RG   +KG++    P  +D +  +  +  A+ P+ P         P  
Sbjct: 1751 RGPPGPQGDPGVRGPAGEKGDRG---PPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGR 1807

Query: 279  RHIPANRGEIKGSESATYVPVAPPTPAWQPEIKPEPAWHDQD-ETSSVKSDGAGGARASF 337
              +P  RG     E     P  PP    +P    +P  + ++ E      DG  G +   
Sbjct: 1808 DGLPGLRG-----EQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDS 1862

Query: 338  RGRGRGRGRGRGRGRGGTRTHFDYQFGYRKFDGVEGPRTP 377
               GR        GR G +       G R   G+ GP+ P
Sbjct: 1863 GASGR-------EGRDGPK-------GERGAPGILGPQGP 1888


>gi|149158690 HLA-B associated transcript-2 [Homo sapiens]
          Length = 2157

 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 57/228 (25%), Positives = 88/228 (38%), Gaps = 26/228 (11%)

Query: 90  SDGEEG--GGEPGAGGGAAGAAGAGRRDFVEAPPPKVNPWTKNALPPVLTTVNGQS--PP 145
           SD E+G    E GA G     + +G     EA   K N  + N+ PP   T   ++  PP
Sbjct: 342 SDEEDGRDSDEEGAEGHRDSQSASGEERPPEADGKKGN--SPNSEPPTPKTAWAETSRPP 399

Query: 146 EHSAPAKVVRAAVPKQRKGSKVGDFGDAINWPTPGEIAHKSVQPQSHKPQPTRKLPPKKD 205
           E        +  +P   +G        A NW  PG+   +   P    P P  +    + 
Sbjct: 400 ETEPGPPAPKPPLPPPHRGP-------AGNWGPPGDYPDRG-GPPCKPPAPEDEDEAWRQ 451

Query: 206 MKEQEKGEGSDSKESPKTKSDESGEEKNGDEDCQRGGQKKKGNKHKWVPLQIDMKPEVPR 265
            ++Q   E S + E  + + +E  EE+   E+ +    +K          ++D K   P 
Sbjct: 452 RRKQSSSEISLAVERARRRREE--EERRMQEERRAACAEKLK--------RLDEKFGAPD 501

Query: 266 EKLASRPTRPPEPRHIPANRGEIKGSESATYVPVAPPTPAWQPEIKPE 313
           ++L + P  PP     PA    +     A   P  PP  A  PE +PE
Sbjct: 502 KRLKAEPAAPPAAPSTPAPPPAVPKELPAP--PAPPPASAPTPETEPE 547



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 89/387 (22%), Positives = 128/387 (33%), Gaps = 104/387 (26%)

Query: 29   PPPAPEGKGEPG-PNDVRGGEPDGSARRPRP-PCAKPHKEGTGQQER-ESPRPLQLPGAE 85
            PPP P     PG P +   G P        P P   P   G+ +  + ++P P + P  E
Sbjct: 829  PPPPPYLASYPGFPENGAPGPPISRFPLEEPGPRPLPWPPGSDEVAKIQTPPPKKEPPKE 888

Query: 86   GPAISDGEEGGGEPGAGGGAAGAAGAGRRDFVEAPPPKVNPWTKNALPPVLTTVNGQSPP 145
              A   G E G +P  G G+ G            PPP+    T+    P   +     PP
Sbjct: 889  ETAQLTGPEAGRKPARGVGSGGQG---------PPPPRRESRTETRWGPRPGSSRRGIPP 939

Query: 146  EHSAPAKVVRAAVPKQRKGSKVGDFGDAINWPTPGEIAHKSVQPQSHKPQPTRKLPPKKD 205
            E   P    R A P ++              P P ++     +P     +  +  PPK D
Sbjct: 940  EE--PGAPPRRAGPIKKP-------------PPPTKVEELPPKPLEQGDETPK--PPKPD 982

Query: 206  MKEQEKGEGSDSKESP---------KTKSDESGEEKNGDEDCQ--------------RG- 241
              +  KG+    KE+P         + + D S  E+ G   C+              RG 
Sbjct: 983  PLKITKGKLGGPKETPPNGNLSPAPRLRRDYS-YERVGPTSCRGRGRGEYFARGRGFRGT 1041

Query: 242  -GQKKKGNKHKWVPLQIDMKPEVPREKLASRPTRPPEPRHIPANRGEIKGSE-------- 292
             G + +G + +      + + +  R      P  PP PR   A+    +GSE        
Sbjct: 1042 YGGRGRGARSREFRSYREFRGDDGRGGGTGGPNHPPAPRGRTASETRSEGSEYEEIPKRR 1101

Query: 293  -----------------------------SATYVPVAPPTPAWQPEIKPEPAWHDQDETS 323
                                         + T VP+APP P   P   P PA        
Sbjct: 1102 RQRGSETGSETHESDLAPSDKEAPTPKEGTLTQVPLAPPPPGAPP--SPAPA-------- 1151

Query: 324  SVKSDGAGGARASFRGRGRGRGRGRGR 350
              +    GG   + RG    RGRG GR
Sbjct: 1152 --RFTARGGRVFTPRGVPSRRGRGGGR 1176



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 72/324 (22%), Positives = 101/324 (31%), Gaps = 62/324 (19%)

Query: 19  EEHGGLVRKKPPPAPEGKGEPGPNDVRGGEPDGSARRPRPPCAKPHKEGTGQQERESPRP 78
           E   G    KPP  P  +G  G     G  PD      +PP  +   E   Q+ ++S   
Sbjct: 400 ETEPGPPAPKPPLPPPHRGPAGNWGPPGDYPDRGGPPCKPPAPEDEDEAWRQRRKQSSSE 459

Query: 79  LQLPGAEGPAISDGEEG----------------------------GGEPGAGGGAAGAAG 110
           + L         + EE                               EP A   A     
Sbjct: 460 ISLAVERARRRREEEERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTPA 519

Query: 111 AGRRDFVEAPPPKVNPWTKNALPPVLTTVNGQSPPEHSAPAKVVRAAVPKQRKGSKVGDF 170
                  E P P   P      P        Q+PP  S P   V AA P    G      
Sbjct: 520 PPPAVPKELPAPPAPPPASAPTPETEPEEPAQAPPAQSTPTPGV-AAAPTLVSG------ 572

Query: 171 GDAINWPTPGEIAHKSVQPQ---SHKPQPTRKLPPKKD---MKEQEKGEG-SDSKESPKT 223
           G + +  + G      V+PQ      P+P  ++PP       K + KG+G   +++ P  
Sbjct: 573 GGSTSSTSSGSFEASPVEPQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQ 632

Query: 224 KSDESGEEKNGDEDCQRGGQK---KKGNKHKWVPLQIDMKPEVPREKLASRPTRPPEPRH 280
                  +K+     QR  Q+   K+  +H+W   Q    P  P       P  PP+P  
Sbjct: 633 GLGYPKYQKSLPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPTP------VPPSPPQPVT 686

Query: 281 IPANRGEIKGSESATYVPVAPPTP 304
           +            A   P APP P
Sbjct: 687 L-----------GAVPAPQAPPPP 699



 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 66/289 (22%), Positives = 112/289 (38%), Gaps = 58/289 (20%)

Query: 113  RRDFVEAPPPKVNPWTKNALPPVLTTVNGQSPPEHSAPAKVVRAAVPKQRKGSKVGDFGD 172
            R +    PPP          PP L +  G   PE+ AP   + +  P +  G +      
Sbjct: 822  RSETPPVPPP----------PPYLASYPGF--PENGAPGPPI-SRFPLEEPGPR------ 862

Query: 173  AINWPTPG--EIAHKSVQPQSHKP--QPTRKLPPKKDMKEQEKGEGSDSKESPKTKSDES 228
             + WP PG  E+A     P   +P  + T +L   +  ++  +G GS  +  P  + +  
Sbjct: 863  PLPWP-PGSDEVAKIQTPPPKKEPPKEETAQLTGPEAGRKPARGVGSGGQGPPPPRRESR 921

Query: 229  GEEKNGDEDCQRGGQKKKGN---------------KHKWVPLQIDMKPEVPREKLASRPT 273
             E + G     R G  ++G                K    P +++  P  P E+    P 
Sbjct: 922  TETRWGP----RPGSSRRGIPPEEPGAPPRRAGPIKKPPPPTKVEELPPKPLEQGDETP- 976

Query: 274  RPPEPRHIPANRGEIKGSESATYVPVAPPTPAWQPEIKPEPAWHDQDETSSVKSDGAGGA 333
            +PP+P  +   +G++ G +     P    +PA  P ++ + ++     TS       G  
Sbjct: 977  KPPKPDPLKITKGKLGGPKETP--PNGNLSPA--PRLRRDYSYERVGPTSC-----RGRG 1027

Query: 334  RASFRGRGRG-----RGRGRGRGRGGTRTHFDYQFGYRKFDGVEGPRTP 377
            R  +  RGRG      GRGRG      R++ +++    +  G  GP  P
Sbjct: 1028 RGEYFARGRGFRGTYGGRGRGARSREFRSYREFRGDDGRGGGTGGPNHP 1076



 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 91/376 (24%), Positives = 133/376 (35%), Gaps = 69/376 (18%)

Query: 26   RKKPPPA---PEGKGEPGPNDVRGGEPDGSARRPRPPCAKPHKEGTGQQ--------ERE 74
            ++ PPP    P+  G PG     GG   G +   R   ++  K+ + +         ER+
Sbjct: 1338 KEAPPPVLLTPKAVGTPGGGG--GGAVPGISAMSRGDLSQRAKDLSKRSFSSQRPGMERQ 1395

Query: 75   SPRPLQLPGAEGPAISDGEEGGGEPGAGGGAAGAAGAGRRDFVEAPPPKVNPWTKNALPP 134
            + RP       GP    G  G    G GGG  G  G GR D    P PK         PP
Sbjct: 1396 NRRP-------GPGGKAGSSGSSSGGGGGGPGGRTGPGRGDKRSWPSPKNRSRPPEERPP 1448

Query: 135  VLTTVNGQSPPE-----------HSAPAKVVRA-AVPKQRKGSKVGDFGDAINWPTPGEI 182
             L       PP            HS PA + +A A    R+GS              G  
Sbjct: 1449 GLPL--PPPPPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQGSVTA---------PGGHP 1497

Query: 183  AHKSVQPQSHKPQ-PTRKLPPKKDMKEQEKGEGSDSK-ESP--------KTKSDESGEEK 232
             HK   PQ+  PQ P+ + P + + +    G  SD   E P         T  D +G   
Sbjct: 1498 RHKPGLPQA--PQGPSPRPPTRYEPQRVNSGLSSDPHFEEPGPMVRGVGGTPRDSAGVSP 1555

Query: 233  NGDEDCQRGGQKKKGNKHKWVPLQ-----IDMKPEVPREKLASRPTRPP-------EPRH 280
               +  +R  +K +  + + +P       +  KPE P  +  SR T             H
Sbjct: 1556 FPPKRRERPPRKPELLQEESLPPPHSSGFLGSKPEGPGPQAESRDTGTEALTPHIWNRLH 1615

Query: 281  IPANRGEIKGSESATYV-PVAPPTPAWQPEIKPEPAWHDQDETSSVKSDGAGGARASFRG 339
               +R   + S    ++ P++P       E+    +  D    S V S G    R+S  G
Sbjct: 1616 TATSRKSYRPSSMEPWMEPLSPFEDVAGTEMSQSDSGVDLSGDSQV-SSGPCSQRSSPDG 1674

Query: 340  RGRGRGRGRGRGRGGT 355
              +G   G  +  GG+
Sbjct: 1675 GLKGAAEGPPKRPGGS 1690



 Score = 31.2 bits (69), Expect = 5.6
 Identities = 46/181 (25%), Positives = 68/181 (37%), Gaps = 23/181 (12%)

Query: 723 LTPEPPVDPNQEVPPGPPRFQQVPTDALANKLFGAPEPSTIARSLPTTVPE----SPNYR 778
           L  EP   P     P PP        A+  +L   P P   +   P T PE    +P  +
Sbjct: 504 LKAEPAAPPAAPSTPAPP-------PAVPKELPAPPAPPPASAPTPETEPEEPAQAPPAQ 556

Query: 779 NTRTPRTPRTPQL-KDSSQTSRFYPVVKEGRTLDAKMPRKRKTRHSSNPPLESHVGWVMD 837
           +T TP     P L      TS       E   ++ ++P K        PP E        
Sbjct: 557 STPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSK----EGPEPPEEVPPPTTPP 612

Query: 838 SREHRPRTASISSSPSEGTPTVG-SYGCTPQSL-PKFQHPSHE-LLKENGFTQHVYHKYR 894
             +  P+   I   P+   P+ G  Y    +SL P+FQ    E LLK+    QH + +++
Sbjct: 613 VPKVEPKGDGI--GPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQ--QQHQWQQHQ 668

Query: 895 R 895
           +
Sbjct: 669 Q 669



 Score = 31.2 bits (69), Expect = 5.6
 Identities = 27/79 (34%), Positives = 29/79 (36%), Gaps = 4/79 (5%)

Query: 22   GGLVRKKPPPAPEGKGEPGPNDVRGGEPDGSARRPRPPCAKPHKEGTGQQERESPRPLQL 81
            GGL      P     G    N V    P GS   PR P   PH     +  RE P P   
Sbjct: 1674 GGLKGAAEGPPKRPGGSSPLNAVPCEGPPGS-EPPRRPPPAPHDGDRKELPREQPLP--- 1729

Query: 82   PGAEGPAISDGEEGGGEPG 100
            PG  G   S   + G EPG
Sbjct: 1730 PGPIGTERSQRTDRGTEPG 1748


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.133    0.400 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 55,590,193
Number of Sequences: 37866
Number of extensions: 3504926
Number of successful extensions: 28517
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 190
Number of HSP's successfully gapped in prelim test: 1093
Number of HSP's that attempted gapping in prelim test: 19769
Number of HSP's gapped (non-prelim): 7728
length of query: 1096
length of database: 18,247,518
effective HSP length: 113
effective length of query: 983
effective length of database: 13,968,660
effective search space: 13731192780
effective search space used: 13731192780
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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